data_A1L8T
# 
_chem_comp.id                                    A1L8T 
_chem_comp.name                                  "~{N}-[5-[[6-[(3~{R})-3-[3,5-bis(fluoranyl)phenyl]-1,2-oxazolidin-2-yl]pyrimidin-4-yl]amino]-2-[4-(4-cyclopropylpiperazin-1-yl)piperidin-1-yl]-4-methoxy-phenyl]propanamide" 
_chem_comp.type                                  non-polymer 
_chem_comp.pdbx_type                             HETAIN 
_chem_comp.formula                               "C35 H44 F2 N8 O3" 
_chem_comp.mon_nstd_parent_comp_id               ? 
_chem_comp.pdbx_synonyms                         ? 
_chem_comp.pdbx_formal_charge                    0 
_chem_comp.pdbx_initial_date                     2025-03-28 
_chem_comp.pdbx_modified_date                    2025-11-07 
_chem_comp.pdbx_ambiguous_flag                   N 
_chem_comp.pdbx_release_status                   REL 
_chem_comp.pdbx_replaced_by                      ? 
_chem_comp.pdbx_replaces                         ? 
_chem_comp.formula_weight                        662.772 
_chem_comp.one_letter_code                       ? 
_chem_comp.three_letter_code                     A1L8T 
_chem_comp.pdbx_model_coordinates_details        ? 
_chem_comp.pdbx_model_coordinates_missing_flag   N 
_chem_comp.pdbx_ideal_coordinates_details        Corina 
_chem_comp.pdbx_ideal_coordinates_missing_flag   N 
_chem_comp.pdbx_model_coordinates_db_code        9U8C 
_chem_comp.pdbx_subcomponent_list                ? 
_chem_comp.pdbx_processing_site                  PDBJ 
_chem_comp.pdbx_pcm                              Y 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.alt_atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.charge 
_chem_comp_atom.pdbx_align 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_leaving_atom_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_n_terminal_atom_flag 
_chem_comp_atom.pdbx_backbone_atom_flag 
_chem_comp_atom.pdbx_c_terminal_atom_flag 
_chem_comp_atom.model_Cartn_x 
_chem_comp_atom.model_Cartn_y 
_chem_comp_atom.model_Cartn_z 
_chem_comp_atom.pdbx_model_Cartn_x_ideal 
_chem_comp_atom.pdbx_model_Cartn_y_ideal 
_chem_comp_atom.pdbx_model_Cartn_z_ideal 
_chem_comp_atom.pdbx_component_atom_id 
_chem_comp_atom.pdbx_component_comp_id 
_chem_comp_atom.pdbx_ordinal 
A1L8T C02  C1  C 0 1 Y N N N N N -44.481 -9.423  33.829 5.496   -1.328 2.021  C02  A1L8T 1  
A1L8T C03  C2  C 0 1 Y N N N N N -44.161 -9.743  32.506 4.764   -0.156 2.119  C03  A1L8T 2  
A1L8T C04  C3  C 0 1 Y N N N N N -43.112 -9.098  31.831 5.314   1.040  1.698  C04  A1L8T 3  
A1L8T C05  C4  C 0 1 N N R N N N -42.747 -9.459  30.359 4.517   2.314  1.804  C05  A1L8T 4  
A1L8T C06  C5  C 0 1 N N N N N N -41.301 -10.200 30.389 5.431   3.483  2.237  C06  A1L8T 5  
A1L8T C07  C6  C 0 1 N N N N N N -41.545 -11.395 30.851 4.912   4.655  1.365  C07  A1L8T 6  
A1L8T C10  C7  C 0 1 Y N N N N N -44.909 -10.076 29.376 4.288   1.740  -0.474 C10  A1L8T 7  
A1L8T C11  C8  C 0 1 Y N N N N N -45.595 -10.995 28.576 3.321   0.824  -0.876 C11  A1L8T 8  
A1L8T C12  C9  C 0 1 Y N N N N N -46.882 -10.634 28.155 3.668   -0.123 -1.836 C12  A1L8T 9  
A1L8T C14  C10 C 0 1 Y N N N N N -47.742 -12.957 27.258 1.410   -0.981 -1.832 C14  A1L8T 10 
A1L8T C15  C11 C 0 1 Y N N N N N -48.897 -13.641 27.670 0.580   0.034  -2.300 C15  A1L8T 11 
A1L8T C17  C12 C 0 1 N N N N N N -51.203 -13.235 27.480 0.154   1.967  -3.619 C17  A1L8T 12 
A1L8T C18  C13 C 0 1 Y N N N N N -48.939 -15.049 27.608 -0.734  0.110  -1.867 C18  A1L8T 13 
A1L8T C19  C14 C 0 1 Y N N N N N -47.831 -15.762 27.124 -1.223  -0.826 -0.968 C19  A1L8T 14 
A1L8T C21  C15 C 0 1 N N N N N N -46.952 -18.077 27.976 -3.486  -0.855 -1.659 C21  A1L8T 15 
A1L8T C22  C16 C 0 1 N N N N N N -47.455 -19.518 28.124 -4.921  -0.913 -1.132 C22  A1L8T 16 
A1L8T C23  C17 C 0 1 N N N N N N -47.614 -20.181 26.823 -5.214  0.352  -0.321 C23  A1L8T 17 
A1L8T C25  C18 C 0 1 N N N N N N -49.003 -21.953 26.596 -6.886  1.477  1.021  C25  A1L8T 18 
A1L8T C26  C19 C 0 1 N N N N N N -49.035 -23.499 26.692 -8.275  1.324  1.647  C26  A1L8T 19 
A1L8T C28  C20 C 0 1 N N N N N N -47.537 -25.026 27.264 -10.626 1.042  1.140  C28  A1L8T 20 
A1L8T C29  C21 C 0 1 N N N N N N -47.735 -26.442 26.698 -11.673 2.007  0.582  C29  A1L8T 21 
A1L8T C30  C22 C 0 1 N N N N N N -48.149 -26.131 28.139 -11.109 2.220  1.988  C30  A1L8T 22 
A1L8T C31  C23 C 0 1 N N N N N N -46.794 -23.264 26.191 -8.953  -0.083 -0.202 C31  A1L8T 23 
A1L8T C32  C24 C 0 1 N N N N N N -46.791 -22.151 27.258 -7.565  0.070  -0.828 C32  A1L8T 24 
A1L8T C33  C25 C 0 1 N N N N N N -48.532 -19.459 25.933 -4.198  0.465  0.819  C33  A1L8T 25 
A1L8T C34  C26 C 0 1 N N N N N N -48.064 -18.004 25.726 -2.783  0.483  0.236  C34  A1L8T 26 
A1L8T C35  C27 C 0 1 Y N N N N N -46.671 -15.083 26.699 -0.393  -1.843 -0.500 C35  A1L8T 27 
A1L8T C37  C28 C 0 1 N N N N N N -44.092 -15.584 26.543 -0.379  -4.039 0.425  C37  A1L8T 28 
A1L8T C38  C29 C 0 1 N N N N N N -42.974 -16.475 25.961 -0.956  -5.076 1.354  C38  A1L8T 29 
A1L8T C39  C30 C 0 1 N N N N N N -42.343 -15.839 24.727 -0.204  -6.396 1.175  C39  A1L8T 30 
A1L8T C41  C31 C 0 1 Y N N N N N -46.633 -13.677 26.769 0.920   -1.922 -0.938 C41  A1L8T 31 
A1L8T C43  C32 C 0 1 Y N N N N N -46.689 -8.619  29.270 5.792   0.768  -1.925 C43  A1L8T 32 
A1L8T C45  C33 C 0 1 Y N N N N N -42.368 -8.131  32.495 6.595   1.068  1.180  C45  A1L8T 33 
A1L8T C46  C34 C 0 1 Y N N N N N -42.694 -7.822  33.813 7.329   -0.103 1.081  C46  A1L8T 34 
A1L8T C48  C35 C 0 1 Y N N N N N -43.740 -8.455  34.484 6.781   -1.300 1.507  C48  A1L8T 35 
A1L8T F01  F1  F 0 1 N N N N N N -45.502 -10.043 34.491 4.958   -2.497 2.433  F01  A1L8T 36 
A1L8T F47  F2  F 0 1 N N N N N N -41.980 -6.874  34.475 8.580   -0.075 0.574  F47  A1L8T 37 
A1L8T N09  N1  N 0 1 N N N N N N -43.556 -10.341 29.885 3.991   2.702  0.479  N09  A1L8T 38 
A1L8T N13  N2  N 0 1 N N N N N N -47.724 -11.479 27.306 2.741   -1.057 -2.271 N13  A1L8T 39 
A1L8T N20  N3  N 0 1 N N N N N N -47.864 -17.245 27.058 -2.552  -0.748 -0.530 N20  A1L8T 40 
A1L8T N24  N4  N 0 1 N N N N N N -47.929 -21.380 27.242 -6.571  0.276  0.235  N24  A1L8T 41 
A1L8T N27  N5  N 0 1 N N N N N N -47.847 -24.129 26.384 -9.268  1.118  0.584  N27  A1L8T 42 
A1L8T N36  N6  N 0 1 N N N N N N -45.505 -15.871 26.196 -0.888  -2.790 0.409  N36  A1L8T 43 
A1L8T N42  N7  N 0 1 Y N N N N N -47.369 -9.461  28.515 4.905   -0.117 -2.332 N42  A1L8T 44 
A1L8T N44  N8  N 0 1 Y N N N N N -45.473 -8.921  29.691 5.504   1.675  -1.014 N44  A1L8T 45 
A1L8T O08  O1  O 0 1 N N N N N N -42.969 -11.713 30.388 4.582   4.000  0.119  O08  A1L8T 46 
A1L8T O16  O2  O 0 1 N N N N N N -50.005 -12.911 28.150 1.060   0.953  -3.181 O16  A1L8T 47 
A1L8T O40  O3  O 0 1 N N N N N N -43.782 -14.674 27.239 0.543   -4.327 -0.308 O40  A1L8T 48 
A1L8T H031 H1  H 0 0 N N N N N N -44.733 -10.502 31.993 3.763   -0.177 2.524  H031 A1L8T 49 
A1L8T H051 H2  H 0 0 N N N N N N -42.670 -8.542  29.756 3.699   2.189  2.514  H051 A1L8T 50 
A1L8T H062 H3  H 0 0 N N N N N N -40.874 -10.256 29.377 5.303   3.703  3.297  H062 A1L8T 51 
A1L8T H061 H4  H 0 0 N N N N N N -40.605 -9.664  31.051 6.475   3.263  2.013  H061 A1L8T 52 
A1L8T H072 H5  H 0 0 N N N N N N -40.832 -12.123 30.437 4.025   5.105  1.811  H072 A1L8T 53 
A1L8T H071 H6  H 0 0 N N N N N N -41.484 -11.405 31.949 5.691   5.402  1.218  H071 A1L8T 54 
A1L8T H111 H7  H 0 0 N N N N N N -45.153 -11.940 28.295 2.327   0.846  -0.455 H111 A1L8T 55 
A1L8T H173 H8  H 0 0 N N N N N N -52.029 -12.638 27.894 -0.699  1.503  -4.114 H173 A1L8T 56 
A1L8T H172 H9  H 0 0 N N N N N N -51.094 -13.015 26.408 -0.193  2.540  -2.759 H172 A1L8T 57 
A1L8T H171 H10 H 0 0 N N N N N N -51.421 -14.305 27.615 0.662   2.632  -4.317 H171 A1L8T 58 
A1L8T H181 H11 H 0 0 N N N N N N -49.823 -15.578 27.933 -1.377  0.899  -2.229 H181 A1L8T 59 
A1L8T H212 H12 H 0 0 N N N N N N -45.939 -18.096 27.549 -3.269  -1.761 -2.225 H212 A1L8T 60 
A1L8T H211 H13 H 0 0 N N N N N N -46.922 -17.606 28.970 -3.372  0.014  -2.307 H211 A1L8T 61 
A1L8T H222 H14 H 0 0 N N N N N N -46.731 -20.087 28.726 -5.614  -0.976 -1.971 H222 A1L8T 62 
A1L8T H221 H15 H 0 0 N N N N N N -48.428 -19.504 28.637 -5.040  -1.789 -0.495 H221 A1L8T 63 
A1L8T H231 H16 H 0 0 N N N N N N -46.627 -20.202 26.337 -5.133  1.226  -0.967 H231 A1L8T 64 
A1L8T H251 H17 H 0 0 N N N N N N -49.928 -21.558 27.042 -6.876  2.351  0.370  H251 A1L8T 65 
A1L8T H252 H18 H 0 0 N N N N N N -48.959 -21.672 25.533 -6.144  1.601  1.809  H252 A1L8T 66 
A1L8T H261 H19 H 0 0 N N N N N N -49.308 -23.771 27.722 -8.278  0.466  2.319  H261 A1L8T 67 
A1L8T H262 H20 H 0 0 N N N N N N -49.806 -23.868 25.999 -8.523  2.226  2.207  H262 A1L8T 68 
A1L8T H281 H21 H 0 0 N N N N N N -46.478 -24.936 27.549 -10.962 0.045  1.426  H281 A1L8T 69 
A1L8T H291 H22 H 0 0 N N N N N N -48.503 -26.626 25.933 -11.355 2.699  -0.198 H291 A1L8T 70 
A1L8T H292 H23 H 0 0 N N N N N N -46.863 -27.083 26.503 -12.698 1.646  0.500  H292 A1L8T 71 
A1L8T H301 H24 H 0 0 N N N N N N -49.215 -26.092 28.408 -11.763 1.998  2.832  H301 A1L8T 72 
A1L8T H302 H25 H 0 0 N N N N N N -47.574 -26.549 28.978 -10.420 3.052  2.133  H302 A1L8T 73 
A1L8T H311 H26 H 0 0 N N N N N N -45.850 -23.826 26.255 -9.696  -0.207 -0.990 H311 A1L8T 74 
A1L8T H312 H27 H 0 0 N N N N N N -46.882 -22.807 25.194 -8.965  -0.957 0.449  H312 A1L8T 75 
A1L8T H321 H28 H 0 0 N N N N N N -46.700 -22.618 28.250 -7.317  -0.831 -1.388 H321 A1L8T 76 
A1L8T H322 H29 H 0 0 N N N N N N -45.924 -21.498 27.079 -7.562  0.928  -1.500 H322 A1L8T 77 
A1L8T H332 H30 H 0 0 N N N N N N -48.565 -19.969 24.959 -4.374  1.386  1.375  H332 A1L8T 78 
A1L8T H331 H31 H 0 0 N N N N N N -49.537 -19.454 26.379 -4.305  -0.390 1.488  H331 A1L8T 79 
A1L8T H342 H32 H 0 0 N N N N N N -47.108 -18.016 25.181 -2.673  1.345  -0.421 H342 A1L8T 80 
A1L8T H341 H33 H 0 0 N N N N N N -48.820 -17.473 25.129 -2.057  0.548  1.046  H341 A1L8T 81 
A1L8T H381 H34 H 0 0 N N N N N N -43.401 -17.450 25.683 -0.855  -4.736 2.385  H381 A1L8T 82 
A1L8T H382 H35 H 0 0 N N N N N N -42.197 -16.620 26.726 -2.011  -5.224 1.122  H382 A1L8T 83 
A1L8T H392 H36 H 0 0 N N N N N N -41.552 -16.498 24.338 0.850   -6.247 1.407  H392 A1L8T 84 
A1L8T H393 H37 H 0 0 N N N N N N -43.113 -15.695 23.955 -0.622  -7.146 1.847  H393 A1L8T 85 
A1L8T H391 H38 H 0 0 N N N N N N -41.909 -14.865 24.998 -0.305  -6.735 0.144  H391 A1L8T 86 
A1L8T H411 H39 H 0 0 N N N N N N -45.749 -13.147 26.446 1.563   -2.712 -0.579 H411 A1L8T 87 
A1L8T H431 H40 H 0 0 N N N N N N -47.131 -7.673  29.547 6.786   0.745  -2.346 H431 A1L8T 88 
A1L8T H451 H41 H 0 0 N N N N N N -41.552 -7.628  31.998 7.024   2.003  0.851  H451 A1L8T 89 
A1L8T H481 H42 H 0 0 N N N N N N -43.970 -8.192  35.506 7.353   -2.213 1.435  H481 A1L8T 90 
A1L8T H131 H43 H 0 0 N N N N N N -48.355 -11.005 26.692 3.012   -1.763 -2.878 H131 A1L8T 91 
A1L8T H361 H46 H 0 0 N N N N N N -45.690 -16.642 25.586 -1.596  -2.547 1.026  H361 A1L8T 92 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1L8T C02 F01  SING N N 1  
A1L8T C03 C02  DOUB Y N 2  
A1L8T C04 C03  SING Y N 3  
A1L8T C06 C05  SING N N 4  
A1L8T C07 C06  SING N N 5  
A1L8T O08 C07  SING N N 6  
A1L8T N09 O08  SING N N 7  
A1L8T C10 N09  SING N N 8  
A1L8T C11 C10  DOUB Y N 9  
A1L8T C12 C11  SING Y N 10 
A1L8T C14 N13  SING N N 11 
A1L8T C15 C14  DOUB Y N 12 
A1L8T C17 O16  SING N N 13 
A1L8T O16 C15  SING N N 14 
A1L8T C18 C15  SING Y N 15 
A1L8T C19 C18  DOUB Y N 16 
A1L8T C21 N20  SING N N 17 
A1L8T C22 C21  SING N N 18 
A1L8T C23 C22  SING N N 19 
A1L8T C25 N24  SING N N 20 
A1L8T C26 C25  SING N N 21 
A1L8T N27 C26  SING N N 22 
A1L8T C29 C28  SING N N 23 
A1L8T C30 C29  SING N N 24 
A1L8T C28 N27  SING N N 25 
A1L8T C31 N27  SING N N 26 
A1L8T C32 C31  SING N N 27 
A1L8T N24 C23  SING N N 28 
A1L8T C33 C23  SING N N 29 
A1L8T C34 C33  SING N N 30 
A1L8T N20 C19  SING N N 31 
A1L8T C35 C19  SING Y N 32 
A1L8T C37 N36  SING N N 33 
A1L8T C39 C38  SING N N 34 
A1L8T C38 C37  SING N N 35 
A1L8T O40 C37  DOUB N N 36 
A1L8T N36 C35  SING N N 37 
A1L8T C41 C35  DOUB Y N 38 
A1L8T N13 C12  SING N N 39 
A1L8T N42 C12  DOUB Y N 40 
A1L8T C43 N42  SING Y N 41 
A1L8T N44 C43  DOUB Y N 42 
A1L8T C05 C04  SING N N 43 
A1L8T C45 C04  DOUB Y N 44 
A1L8T C46 C45  SING Y N 45 
A1L8T F47 C46  SING N N 46 
A1L8T C48 C46  DOUB Y N 47 
A1L8T C02 C48  SING Y N 48 
A1L8T C05 N09  SING N N 49 
A1L8T C10 N44  SING Y N 50 
A1L8T C14 C41  SING Y N 51 
A1L8T N20 C34  SING N N 52 
A1L8T N24 C32  SING N N 53 
A1L8T C28 C30  SING N N 54 
A1L8T C03 H031 SING N N 55 
A1L8T C05 H051 SING N N 56 
A1L8T C06 H062 SING N N 57 
A1L8T C06 H061 SING N N 58 
A1L8T C07 H072 SING N N 59 
A1L8T C07 H071 SING N N 60 
A1L8T C11 H111 SING N N 61 
A1L8T C17 H173 SING N N 62 
A1L8T C17 H172 SING N N 63 
A1L8T C17 H171 SING N N 64 
A1L8T C18 H181 SING N N 65 
A1L8T C21 H212 SING N N 66 
A1L8T C21 H211 SING N N 67 
A1L8T C22 H222 SING N N 68 
A1L8T C22 H221 SING N N 69 
A1L8T C23 H231 SING N N 70 
A1L8T C25 H251 SING N N 71 
A1L8T C25 H252 SING N N 72 
A1L8T C26 H261 SING N N 73 
A1L8T C26 H262 SING N N 74 
A1L8T C28 H281 SING N N 75 
A1L8T C29 H291 SING N N 76 
A1L8T C29 H292 SING N N 77 
A1L8T C30 H301 SING N N 78 
A1L8T C30 H302 SING N N 79 
A1L8T C31 H311 SING N N 80 
A1L8T C31 H312 SING N N 81 
A1L8T C32 H321 SING N N 82 
A1L8T C32 H322 SING N N 83 
A1L8T C33 H332 SING N N 84 
A1L8T C33 H331 SING N N 85 
A1L8T C34 H342 SING N N 86 
A1L8T C34 H341 SING N N 87 
A1L8T C38 H381 SING N N 88 
A1L8T C38 H382 SING N N 89 
A1L8T C39 H392 SING N N 90 
A1L8T C39 H393 SING N N 91 
A1L8T C39 H391 SING N N 92 
A1L8T C41 H411 SING N N 93 
A1L8T C43 H431 SING N N 94 
A1L8T C45 H451 SING N N 95 
A1L8T C48 H481 SING N N 96 
A1L8T N13 H131 SING N N 97 
A1L8T N36 H361 SING N N 98 
# 
loop_
_pdbx_chem_comp_descriptor.comp_id 
_pdbx_chem_comp_descriptor.type 
_pdbx_chem_comp_descriptor.program 
_pdbx_chem_comp_descriptor.program_version 
_pdbx_chem_comp_descriptor.descriptor 
A1L8T InChI            InChI                1.06  "InChI=1S/C35H44F2N8O3/c1-3-35(46)41-28-19-29(40-33-21-34(39-22-38-33)45-30(8-15-48-45)23-16-24(36)18-25(37)17-23)32(47-2)20-31(28)44-9-6-27(7-10-44)43-13-11-42(12-14-43)26-4-5-26/h16-22,26-27,30H,3-15H2,1-2H3,(H,41,46)(H,38,39,40)/t30-/m1/s1" 
A1L8T InChIKey         InChI                1.06  SZLYMLSXCABOBL-SSEXGKCCSA-N                                                                                                                                                                                                                         
A1L8T SMILES_CANONICAL CACTVS               3.385 "CCC(=O)Nc1cc(Nc2cc(ncn2)N3OCC[C@@H]3c4cc(F)cc(F)c4)c(OC)cc1N5CCC(CC5)N6CCN(CC6)C7CC7"                                                                                                                                                              
A1L8T SMILES           CACTVS               3.385 "CCC(=O)Nc1cc(Nc2cc(ncn2)N3OCC[CH]3c4cc(F)cc(F)c4)c(OC)cc1N5CCC(CC5)N6CCN(CC6)C7CC7"                                                                                                                                                                
A1L8T SMILES_CANONICAL "OpenEye OEToolkits" 2.0.7 "CCC(=O)Nc1cc(c(cc1N2CCC(CC2)N3CCN(CC3)C4CC4)OC)Nc5cc(ncn5)N6[C@H](CCO6)c7cc(cc(c7)F)F"                                                                                                                                                             
A1L8T SMILES           "OpenEye OEToolkits" 2.0.7 "CCC(=O)Nc1cc(c(cc1N2CCC(CC2)N3CCN(CC3)C4CC4)OC)Nc5cc(ncn5)N6C(CCO6)c7cc(cc(c7)F)F"                                                                                                                                                                 
# 
_pdbx_chem_comp_identifier.comp_id           A1L8T 
_pdbx_chem_comp_identifier.type              "SYSTEMATIC NAME" 
_pdbx_chem_comp_identifier.program           "OpenEye OEToolkits" 
_pdbx_chem_comp_identifier.program_version   2.0.7 
_pdbx_chem_comp_identifier.identifier        "~{N}-[5-[[6-[(3~{R})-3-[3,5-bis(fluoranyl)phenyl]-1,2-oxazolidin-2-yl]pyrimidin-4-yl]amino]-2-[4-(4-cyclopropylpiperazin-1-yl)piperidin-1-yl]-4-methoxy-phenyl]propanamide" 
# 
_pdbx_chem_comp_pcm.pcm_id                             1 
_pdbx_chem_comp_pcm.comp_id                            A1L8T 
_pdbx_chem_comp_pcm.modified_residue_id                CYS 
_pdbx_chem_comp_pcm.type                               None 
_pdbx_chem_comp_pcm.category                           "Covalent chemical modification" 
_pdbx_chem_comp_pcm.position                           "Amino-acid side chain" 
_pdbx_chem_comp_pcm.polypeptide_position               "Any position" 
_pdbx_chem_comp_pcm.comp_id_linking_atom               C39 
_pdbx_chem_comp_pcm.modified_residue_id_linking_atom   SG 
_pdbx_chem_comp_pcm.uniprot_specific_ptm_accession     ? 
_pdbx_chem_comp_pcm.uniprot_generic_ptm_accession      ? 
# 
loop_
_pdbx_chem_comp_audit.comp_id 
_pdbx_chem_comp_audit.action_type 
_pdbx_chem_comp_audit.date 
_pdbx_chem_comp_audit.processing_site 
A1L8T "Create component" 2025-03-28 PDBJ 
A1L8T "Initial release"  2025-11-12 RCSB 
# 
