data_YUM
#

_chem_comp.id                                   YUM
_chem_comp.name                                 "(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-[{4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]-1-{4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl}butan-2-yl]carbamate"
_chem_comp.type                                 non-polymer
_chem_comp.pdbx_type                            HETAIN
_chem_comp.formula                              "C34 H45 N3 O9 S2"
_chem_comp.mon_nstd_parent_comp_id              ?
_chem_comp.pdbx_synonyms                        ?
_chem_comp.pdbx_formal_charge                   0
_chem_comp.pdbx_initial_date                    2021-04-01
_chem_comp.pdbx_modified_date                   2022-04-01
_chem_comp.pdbx_ambiguous_flag                  N
_chem_comp.pdbx_release_status                  REL
_chem_comp.pdbx_replaced_by                     ?
_chem_comp.pdbx_replaces                        ?
_chem_comp.formula_weight                       703.866
_chem_comp.one_letter_code                      ?
_chem_comp.three_letter_code                    YUM
_chem_comp.pdbx_model_coordinates_details       ?
_chem_comp.pdbx_model_coordinates_missing_flag  N
_chem_comp.pdbx_ideal_coordinates_details       Corina
_chem_comp.pdbx_ideal_coordinates_missing_flag  N
_chem_comp.pdbx_model_coordinates_db_code       7M9Q
_chem_comp.pdbx_subcomponent_list               ?
_chem_comp.pdbx_processing_site                 RCSB
#   #
loop_
_chem_comp_atom.comp_id
_chem_comp_atom.atom_id
_chem_comp_atom.alt_atom_id
_chem_comp_atom.type_symbol
_chem_comp_atom.charge
_chem_comp_atom.pdbx_align
_chem_comp_atom.pdbx_aromatic_flag
_chem_comp_atom.pdbx_leaving_atom_flag
_chem_comp_atom.pdbx_stereo_config
_chem_comp_atom.model_Cartn_x
_chem_comp_atom.model_Cartn_y
_chem_comp_atom.model_Cartn_z
_chem_comp_atom.pdbx_model_Cartn_x_ideal
_chem_comp_atom.pdbx_model_Cartn_y_ideal
_chem_comp_atom.pdbx_model_Cartn_z_ideal
_chem_comp_atom.pdbx_component_atom_id
_chem_comp_atom.pdbx_component_comp_id
_chem_comp_atom.pdbx_ordinal
YUM  C13   C1   C  0  1  N  N  R  20.160  -0.628  14.633    1.322  -0.432  -1.830  C13   YUM   1  
YUM  C15   C2   C  0  1  N  N  S  19.780  -0.339  16.108   -0.081  -0.473  -1.222  C15   YUM   2  
YUM  C17   C3   C  0  1  N  N  N  21.763   0.226  17.701   -0.104   1.907  -0.703  C17   YUM   3  
YUM  C20   C4   C  0  1  N  N  R  23.377   1.141  19.284   -0.091   4.270  -0.363  C20   YUM   4  
YUM  C21   C5   C  0  1  N  N  N  24.827   1.645  18.841   -1.451   4.830  -0.817  C21   YUM   5  
YUM  C24   C6   C  0  1  N  N  R  23.635   3.453  19.883   -0.504   6.496   0.494  C24   YUM   6  
YUM  C26   C7   C  0  1  N  N  N  21.274   3.373  19.439   -0.881   5.939   2.714  C26   YUM   7  
YUM  C28   C8   C  0  1  N  N  N  18.443   0.392  16.207   -1.123  -0.345  -2.335  C28   YUM   8  
YUM  C01   C9   C  0  1  Y  N  N  15.576  -6.186  13.031    7.006  -2.909   1.956  C01   YUM   9  
YUM  C02   C10  C  0  1  Y  N  N  16.626  -6.923  13.869    5.743  -3.437   1.762  C02   YUM  10  
YUM  C03   C11  C  0  1  Y  N  N  17.547  -6.146  14.764    5.007  -3.080   0.648  C03   YUM  11  
YUM  C04   C12  C  0  1  Y  N  N  17.396  -4.655  14.772    5.534  -2.193  -0.273  C04   YUM  12  
YUM  C05   C13  C  0  1  Y  N  N  16.389  -3.907  13.923    6.797  -1.665  -0.079  C05   YUM  13  
YUM  C06   C14  C  0  1  Y  N  N  15.471  -4.692  13.041    7.533  -2.023   1.035  C06   YUM  14  
YUM  C11   C15  C  0  1  N  N  N  20.378  -4.049  13.942    4.261   0.940  -1.487  C11   YUM  15  
YUM  C12   C16  C  0  1  N  N  N  19.215  -1.686  14.094    2.364  -0.560  -0.717  C12   YUM  16  
YUM  C23   C17  C  0  1  N  N  S  22.930   1.990  20.263    0.378   5.234   0.748  C23   YUM  17  
YUM  C25   C18  C  0  1  N  N  N  21.578   2.088  20.244   -0.155   4.726   2.105  C25   YUM  18  
YUM  C29   C19  C  0  1  Y  N  N  18.211   0.787  17.688   -2.503  -0.509  -1.753  C29   YUM  19  
YUM  C30   C20  C  0  1  Y  N  N  18.222   2.282  18.111   -3.194   0.597  -1.295  C30   YUM  20  
YUM  C31   C21  C  0  1  Y  N  N  18.010   2.639  19.583   -4.460   0.450  -0.761  C31   YUM  21  
YUM  C32   C22  C  0  1  Y  N  N  17.795   1.515  20.599   -5.037  -0.810  -0.684  C32   YUM  22  
YUM  C33   C23  C  0  1  Y  N  N  17.774   0.021  20.169   -4.341  -1.918  -1.144  C33   YUM  23  
YUM  C34   C24  C  0  1  Y  N  N  17.975  -0.327  18.719   -3.078  -1.764  -1.683  C34   YUM  24  
YUM  C36   C25  C  0  1  N  N  N  21.920  -3.734  13.996    4.949   1.408  -0.204  C36   YUM  25  
YUM  C37   C26  C  0  1  N  N  N  22.496  -3.820  15.389    5.657   2.739  -0.461  C37   YUM  26  
YUM  C38   C27  C  0  1  N  N  N  22.652  -4.743  13.040    3.904   1.590   0.899  C38   YUM  27  
YUM  C39   C28  C  0  1  N  N  S  14.655  -7.035  12.085    7.805  -3.294   3.174  C39   YUM  28  
YUM  C40   C29  C  0  1  N  N  N  18.659   1.890  22.854   -6.812  -2.283  -0.111  C40   YUM  29  
YUM  C41   C30  C  0  1  N  N  N  14.409  -8.403  12.691    7.598  -2.248   4.271  C41   YUM  30  
YUM  C42   C31  C  0  1  Y  N  N  17.973   2.157  24.228   -8.190  -2.251   0.499  C42   YUM  31  
YUM  C43   C32  C  0  1  Y  N  N  17.958   1.260  25.351   -8.771  -1.121   0.912  C43   YUM  32  
YUM  C45   C33  C  0  1  Y  N  N  16.672   3.265  25.955  -10.088  -3.181   1.196  C45   YUM  33  
YUM  C47   C34  C  0  1  N  N  N  15.824   4.285  26.738  -11.067  -4.295   1.463  C47   YUM  34  
YUM  N10   N1   N  0  1  N  N  N  19.636  -3.019  14.724    3.706  -0.401  -1.283  N10   YUM  35  
YUM  N16   N2   N  0  1  N  N  N  20.779   0.572  16.623   -0.237   0.636  -0.278  N16   YUM  36  
YUM  N46   N3   N  0  1  Y  N  N  17.147   3.420  24.609   -8.923  -3.334   0.662  N46   YUM  37  
YUM  O08   O1   O  0  1  N  N  N  19.139  -4.557  16.732    5.532  -1.309  -2.672  O08   YUM  38  
YUM  O09   O2   O  0  1  N  N  N  17.681  -2.577  16.405    3.664  -2.786  -1.913  O09   YUM  39  
YUM  O14   O3   O  0  1  N  N  N  20.097   0.564  13.940    1.475  -1.513  -2.752  O14   YUM  40  
YUM  O18   O4   O  0  1  N  N  N  21.789  -0.837  18.283    0.145   2.134  -1.871  O18   YUM  41  
YUM  O19   O5   O  0  1  N  N  N  22.676   1.284  18.025   -0.248   2.926   0.165  O19   YUM  42  
YUM  O22   O6   O  0  1  N  N  N  24.555   3.222  18.887   -1.751   5.957   0.019  O22   YUM  43  
YUM  O27   O7   O  0  1  N  N  N  22.645   4.229  19.526   -0.706   7.042   1.811  O27   YUM  44  
YUM  O35   O8   O  0  1  N  N  N  17.568   1.820  21.954   -6.281  -0.957  -0.158  O35   YUM  45  
YUM  O48   O9   O  0  1  N  N  N  15.426  -7.056  10.940    9.191  -3.360   2.833  O48   YUM  46  
YUM  S07   S1   S  0  1  N  N  N  18.464  -3.662  15.803    4.596  -1.736  -1.692  S07   YUM  47  
YUM  S44   S2   S  0  1  Y  N  N  17.157   1.917  26.465  -10.361  -1.531   1.553  S44   YUM  48  
YUM  H131  H1   H  0  0  N  N  N  21.184  -1.030  14.615    1.464   0.514  -2.353  H131  YUM  49  
YUM  H151  H2   H  0  0  N  N  N  19.750  -1.276  16.683   -0.223  -1.419  -0.699  H151  YUM  50  
YUM  H201  H3   H  0  0  N  N  N  23.430   0.091  19.609    0.617   4.272  -1.192  H201  YUM  51  
YUM  H211  H4   H  0  0  N  N  N  25.608   1.338  19.553   -1.392   5.146  -1.859  H211  YUM  52  
YUM  H212  H5   H  0  0  N  N  N  25.095   1.300  17.831   -2.222   4.068  -0.703  H212  YUM  53  
YUM  H241  H6   H  0  0  N  N  N  24.132   3.816  20.795   -0.052   7.201  -0.205  H241  YUM  54  
YUM  H261  H7   H  0  0  N  N  N  21.031   3.130  18.394   -1.942   5.718   2.827  H261  YUM  55  
YUM  H262  H8   H  0  0  N  N  N  20.438   3.928  19.890   -0.447   6.183   3.684  H262  YUM  56  
YUM  H281  H9   H  0  0  N  N  N  18.466   1.296  15.581   -1.039   0.637  -2.800  H281  YUM  57  
YUM  H282  H10  H  0  0  N  N  N  17.632  -0.269  15.867   -0.951  -1.118  -3.085  H282  YUM  58  
YUM  H021  H11  H  0  0  N  N  N  16.703  -7.999  13.816    5.331  -4.130   2.482  H021  YUM  59  
YUM  H031  H12  H  0  0  N  N  N  18.287  -6.640  15.376    4.021  -3.493   0.497  H031  YUM  60  
YUM  H051  H13  H  0  0  N  N  N  16.335  -2.829  13.954    7.208  -0.973  -0.799  H051  YUM  61  
YUM  H061  H14  H  0  0  N  N  N  14.744  -4.189  12.421    8.519  -1.611   1.185  H061  YUM  62  
YUM  H111  H15  H  0  0  N  N  N  20.036  -4.033  12.897    3.457   1.631  -1.741  H111  YUM  63  
YUM  H112  H16  H  0  0  N  N  N  20.191  -5.043  14.374    4.986   0.913  -2.300  H112  YUM  64  
YUM  H122  H17  H  0  0  N  N  N  18.179  -1.446  14.373    2.192   0.213   0.032  H122  YUM  65  
YUM  H121  H18  H  0  0  N  N  N  19.296  -1.743  12.998    2.280  -1.542  -0.252  H121  YUM  66  
YUM  H231  H19  H  0  0  N  N  N  23.302   1.692  21.254    1.450   5.431   0.731  H231  YUM  67  
YUM  H251  H20  H  0  0  N  N  N  21.183   2.172  21.267    0.670   4.415   2.746  H251  YUM  68  
YUM  H252  H21  H  0  0  N  N  N  21.135   1.210  19.751   -0.853   3.902   1.955  H252  YUM  69  
YUM  H301  H22  H  0  0  N  N  N  18.377   3.058  17.376   -2.745   1.577  -1.354  H301  YUM  70  
YUM  H311  H23  H  0  0  N  N  N  18.012   3.671  19.901   -4.999   1.314  -0.402  H311  YUM  71  
YUM  H331  H24  H  0  0  N  N  N  17.617  -0.757  20.902   -4.788  -2.899  -1.086  H331  YUM  72  
YUM  H341  H25  H  0  0  N  N  N  17.953  -1.360  18.403   -2.538  -2.626  -2.045  H341  YUM  73  
YUM  H361  H26  H  0  0  N  N  N  22.076  -2.717  13.607    5.681   0.662   0.109  H361  YUM  74  
YUM  H371  H27  H  0  0  N  N  N  23.571  -3.590  15.357    4.926   3.485  -0.774  H371  YUM  75  
YUM  H373  H28  H  0  0  N  N  N  21.986  -3.096  16.042    6.148   3.073   0.453  H373  YUM  76  
YUM  H372  H29  H  0  0  N  N  N  22.350  -4.836  15.784    6.402   2.609  -1.246  H372  YUM  77  
YUM  H381  H30  H  0  0  N  N  N  23.734  -4.546  13.057    3.495   0.619   1.176  H381  YUM  78  
YUM  H383  H31  H  0  0  N  N  N  22.461  -5.772  13.378    4.371   2.050   1.770  H383  YUM  79  
YUM  H382  H32  H  0  0  N  N  N  22.273  -4.617  12.015    3.102   2.233   0.536  H382  YUM  80  
YUM  H391  H33  H  0  0  N  N  N  13.700  -6.509  11.935    7.473  -4.268   3.533  H391  YUM  81  
YUM  H401  H34  H  0  0  N  N  N  19.339   2.712  22.586   -6.162  -2.914   0.495  H401  YUM  82  
YUM  H402  H35  H  0  0  N  N  N  19.218   0.943  22.870   -6.872  -2.687  -1.122  H402  YUM  83  
YUM  H412  H36  H  0  0  N  N  N  13.763  -8.990  12.022    6.541  -2.198   4.531  H412  YUM  84  
YUM  H411  H37  H  0  0  N  N  N  15.369  -8.923  12.824    8.176  -2.526   5.152  H411  YUM  85  
YUM  H413  H38  H  0  0  N  N  N  13.916  -8.288  13.668    7.930  -1.274   3.911  H413  YUM  86  
YUM  H431  H39  H  0  0  N  N  N  18.432   0.291  25.396   -8.343  -0.131   0.863  H431  YUM  87  
YUM  H472  H42  H  0  0  N  N  N  15.632   5.165  26.106  -10.894  -4.700   2.460  H472  YUM  88  
YUM  H471  H43  H  0  0  N  N  N  14.868   3.823  27.025  -12.084  -3.908   1.400  H471  YUM  89  
YUM  H473  H44  H  0  0  N  N  N  16.367   4.595  27.643  -10.932  -5.083   0.723  H473  YUM  90  
YUM  H161  H45  H  0  0  N  N  N  20.816   1.493  16.235   -0.436   0.454   0.654  H161  YUM  91  
YUM  H141  H46  H  0  0  N  N  N  20.326   0.414  13.030    1.362  -2.388  -2.354  H141  YUM  92  
YUM  H481  H47  H  0  0  N  N  N  14.977  -7.551  10.265    9.555  -2.526   2.504  H481  YUM  93  
#   #
loop_
_chem_comp_bond.comp_id
_chem_comp_bond.atom_id_1
_chem_comp_bond.atom_id_2
_chem_comp_bond.value_order
_chem_comp_bond.pdbx_aromatic_flag
_chem_comp_bond.pdbx_stereo_config
_chem_comp_bond.pdbx_ordinal
YUM  C13  C15   SING  N  N   1  
YUM  C13  C12   SING  N  N   2  
YUM  C13  O14   SING  N  N   3  
YUM  C15  C28   SING  N  N   4  
YUM  C15  N16   SING  N  N   5  
YUM  C17  N16   SING  N  N   6  
YUM  C17  O18   DOUB  N  N   7  
YUM  C17  O19   SING  N  N   8  
YUM  C20  C21   SING  N  N   9  
YUM  C20  C23   SING  N  N  10  
YUM  C20  O19   SING  N  N  11  
YUM  C21  O22   SING  N  N  12  
YUM  C24  C23   SING  N  N  13  
YUM  C24  O22   SING  N  N  14  
YUM  C24  O27   SING  N  N  15  
YUM  C26  C25   SING  N  N  16  
YUM  C26  O27   SING  N  N  17  
YUM  C28  C29   SING  N  N  18  
YUM  C01  C02   DOUB  Y  N  19  
YUM  C01  C06   SING  Y  N  20  
YUM  C01  C39   SING  N  N  21  
YUM  C02  C03   SING  Y  N  22  
YUM  C03  C04   DOUB  Y  N  23  
YUM  C04  C05   SING  Y  N  24  
YUM  C04  S07   SING  N  N  25  
YUM  C05  C06   DOUB  Y  N  26  
YUM  C11  C36   SING  N  N  27  
YUM  C11  N10   SING  N  N  28  
YUM  C12  N10   SING  N  N  29  
YUM  C23  C25   SING  N  N  30  
YUM  C29  C30   DOUB  Y  N  31  
YUM  C29  C34   SING  Y  N  32  
YUM  C30  C31   SING  Y  N  33  
YUM  C31  C32   DOUB  Y  N  34  
YUM  C32  C33   SING  Y  N  35  
YUM  C32  O35   SING  N  N  36  
YUM  C33  C34   DOUB  Y  N  37  
YUM  C36  C37   SING  N  N  38  
YUM  C36  C38   SING  N  N  39  
YUM  C39  C41   SING  N  N  40  
YUM  C39  O48   SING  N  N  41  
YUM  C40  C42   SING  N  N  42  
YUM  C40  O35   SING  N  N  43  
YUM  C42  C43   DOUB  Y  N  44  
YUM  C42  N46   SING  Y  N  45  
YUM  C43  S44   SING  Y  N  46  
YUM  C45  C47   SING  N  N  47  
YUM  C45  N46   DOUB  Y  N  48  
YUM  C45  S44   SING  Y  N  49  
YUM  N10  S07   SING  N  N  50  
YUM  O08  S07   DOUB  N  N  51  
YUM  O09  S07   DOUB  N  N  52  
YUM  C13  H131  SING  N  N  53  
YUM  C15  H151  SING  N  N  54  
YUM  C20  H201  SING  N  N  55  
YUM  C21  H211  SING  N  N  56  
YUM  C21  H212  SING  N  N  57  
YUM  C24  H241  SING  N  N  58  
YUM  C26  H261  SING  N  N  59  
YUM  C26  H262  SING  N  N  60  
YUM  C28  H281  SING  N  N  61  
YUM  C28  H282  SING  N  N  62  
YUM  C02  H021  SING  N  N  63  
YUM  C03  H031  SING  N  N  64  
YUM  C05  H051  SING  N  N  65  
YUM  C06  H061  SING  N  N  66  
YUM  C11  H111  SING  N  N  67  
YUM  C11  H112  SING  N  N  68  
YUM  C12  H122  SING  N  N  69  
YUM  C12  H121  SING  N  N  70  
YUM  C23  H231  SING  N  N  71  
YUM  C25  H251  SING  N  N  72  
YUM  C25  H252  SING  N  N  73  
YUM  C30  H301  SING  N  N  74  
YUM  C31  H311  SING  N  N  75  
YUM  C33  H331  SING  N  N  76  
YUM  C34  H341  SING  N  N  77  
YUM  C36  H361  SING  N  N  78  
YUM  C37  H371  SING  N  N  79  
YUM  C37  H373  SING  N  N  80  
YUM  C37  H372  SING  N  N  81  
YUM  C38  H381  SING  N  N  82  
YUM  C38  H383  SING  N  N  83  
YUM  C38  H382  SING  N  N  84  
YUM  C39  H391  SING  N  N  85  
YUM  C40  H401  SING  N  N  86  
YUM  C40  H402  SING  N  N  87  
YUM  C41  H412  SING  N  N  88  
YUM  C41  H411  SING  N  N  89  
YUM  C41  H413  SING  N  N  90  
YUM  C43  H431  SING  N  N  91  
YUM  C47  H472  SING  N  N  92  
YUM  C47  H471  SING  N  N  93  
YUM  C47  H473  SING  N  N  94  
YUM  N16  H161  SING  N  N  95  
YUM  O14  H141  SING  N  N  96  
YUM  O48  H481  SING  N  N  97  
#   #
loop_
_pdbx_chem_comp_descriptor.comp_id
_pdbx_chem_comp_descriptor.type
_pdbx_chem_comp_descriptor.program
_pdbx_chem_comp_descriptor.program_version
_pdbx_chem_comp_descriptor.descriptor
YUM  SMILES            ACDLabs               12.01  "Cc1nc(COc2ccc(CC(NC(=O)OC3COC4OCCC43)C(O)CN(CC(C)C)S(=O)(=O)c3ccc(cc3)C(C)O)cc2)cs1"  
YUM  InChI             InChI                 1.03   "InChI=1S/C34H45N3O9S2/c1-21(2)16-37(48(41,42)28-11-7-25(8-12-28)22(3)38)17-31(39)30(36-34(40)46-32-19-45-33-29(32)13-14-43-33)15-24-5-9-27(10-6-24)44-18-26-20-47-23(4)35-26/h5-12,20-22,29-33,38-39H,13-19H2,1-4H3,(H,36,40)/t22-,29-,30-,31+,32-,33+/m0/s1"  
YUM  InChIKey          InChI                 1.03   FMJNTAVHNLSSOR-XSXYQVDFSA-N  
YUM  SMILES_CANONICAL  CACTVS                3.385  "CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(OCc2csc(C)n2)cc1)NC(=O)O[C@H]3CO[C@H]4OCC[C@@H]34)[S](=O)(=O)c5ccc(cc5)[C@H](C)O"  
YUM  SMILES            CACTVS                3.385  "CC(C)CN(C[CH](O)[CH](Cc1ccc(OCc2csc(C)n2)cc1)NC(=O)O[CH]3CO[CH]4OCC[CH]34)[S](=O)(=O)c5ccc(cc5)[CH](C)O"  
YUM  SMILES_CANONICAL  "OpenEye OEToolkits"  2.0.7  "Cc1nc(cs1)COc2ccc(cc2)C[C@@H]([C@@H](CN(CC(C)C)S(=O)(=O)c3ccc(cc3)[C@H](C)O)O)NC(=O)O[C@H]4CO[C@@H]5[C@H]4CCO5"  
YUM  SMILES            "OpenEye OEToolkits"  2.0.7  "Cc1nc(cs1)COc2ccc(cc2)CC(C(CN(CC(C)C)S(=O)(=O)c3ccc(cc3)C(C)O)O)NC(=O)OC4COC5C4CCO5"  
#   #
loop_
_pdbx_chem_comp_identifier.comp_id
_pdbx_chem_comp_identifier.type
_pdbx_chem_comp_identifier.program
_pdbx_chem_comp_identifier.program_version
_pdbx_chem_comp_identifier.identifier
YUM  "SYSTEMATIC NAME"  ACDLabs               12.01  "(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-[{4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]-1-{4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl}butan-2-yl]carbamate"  
YUM  "SYSTEMATIC NAME"  "OpenEye OEToolkits"  2.0.7  "[(3~{a}~{S},4~{R},6~{a}~{R})-2,3,3~{a},4,5,6~{a}-hexahydrofuro[2,3-b]furan-4-yl] ~{N}-[(2~{S},3~{R})-4-[2-methylpropyl-[4-[(1~{S})-1-oxidanylethyl]phenyl]sulfonyl-amino]-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]-3-oxidanyl-butan-2-yl]carbamate"  
#   #
loop_
_pdbx_chem_comp_audit.comp_id
_pdbx_chem_comp_audit.action_type
_pdbx_chem_comp_audit.date
_pdbx_chem_comp_audit.processing_site
YUM  "Create component"  2021-04-01  RCSB  
YUM  "Initial release"   2022-04-06  RCSB  
##
