data_8FG2
# 
_entry.id   8FG2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8FG2         pdb_00008fg2 10.2210/pdb8fg2/pdb 
WWPDB D_1000270721 ?            ?                   
EMDB  EMD-29072    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2023-01-11 ? 
2  'EM metadata'     1 0 2023-01-11 ? 
3  FSC               1 0 2023-01-11 ? 
4  'Half map'        1 0 2023-01-11 1 
5  'Half map'        1 0 2023-01-11 2 
6  Image             1 0 2023-01-11 ? 
7  'Primary map'     1 0 2023-01-11 ? 
8  'Structure model' 1 1 2023-10-11 ? 
9  FSC               1 0 2023-01-11 ? 
10 'Half map'        1 0 2023-01-11 1 
11 'Half map'        1 0 2023-01-11 2 
12 Image             1 0 2023-01-11 ? 
13 'Primary map'     1 0 2023-01-11 ? 
14 'Structure model' 1 2 2025-03-05 ? 
15 'EM metadata'     1 1 2025-03-05 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  FSC               repository 'Initial release' ? ? 
4  4  'Half map'        repository 'Initial release' ? ? 
5  5  'Half map'        repository 'Initial release' ? ? 
6  6  Image             repository 'Initial release' ? ? 
7  7  'Primary map'     repository 'Initial release' ? ? 
8  9  FSC               repository 'Initial release' ? ? 
9  10 'Half map'        repository 'Initial release' ? ? 
10 11 'Half map'        repository 'Initial release' ? ? 
11 12 Image             repository 'Initial release' ? ? 
12 13 'Primary map'     repository 'Initial release' ? ? 
13 14 'Structure model' repository Obsolete          ? ? 
14 15 'EM metadata'     repository Obsolete          ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1  8  'Structure model' 'Data collection'      
2  8  'Structure model' 'Database references'  
3  14 'Structure model' Advisory               
4  14 'Structure model' 'Data collection'      
5  14 'Structure model' 'Database references'  
6  14 'Structure model' Other                  
7  14 'Structure model' 'Structure summary'    
8  15 'EM metadata'     Advisory               
9  15 'EM metadata'     'Database references'  
10 15 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1  8  'Structure model' chem_comp_atom            
2  8  'Structure model' chem_comp_bond            
3  8  'Structure model' citation                  
4  8  'Structure model' citation_author           
5  14 'Structure model' citation                  
6  14 'Structure model' citation_author           
7  14 'Structure model' em_admin                  
8  14 'Structure model' pdbx_database_PDB_obs_spr 
9  14 'Structure model' pdbx_database_status      
10 14 'Structure model' pdbx_entry_details        
11 15 'EM metadata'     citation                  
12 15 'EM metadata'     citation_author           
13 15 'EM metadata'     em_admin                  
14 15 'EM metadata'     pdbx_database_PDB_obs_spr 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  14 'Structure model' '_citation.journal_volume'          
2  14 'Structure model' '_citation.page_first'              
3  14 'Structure model' '_citation.page_last'               
4  14 'Structure model' '_citation.pdbx_database_id_DOI'    
5  14 'Structure model' '_citation.pdbx_database_id_PubMed' 
6  14 'Structure model' '_citation.title'                   
7  14 'Structure model' '_citation.year'                    
8  14 'Structure model' '_em_admin.current_status'          
9  14 'Structure model' '_em_admin.last_update'             
10 14 'Structure model' '_pdbx_database_status.status_code' 
11 15 'EM metadata'     '_citation.journal_volume'          
12 15 'EM metadata'     '_citation.page_first'              
13 15 'EM metadata'     '_citation.page_last'               
14 15 'EM metadata'     '_citation.pdbx_database_id_DOI'    
15 15 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
16 15 'EM metadata'     '_citation.title'                   
17 15 'EM metadata'     '_citation.year'                    
18 15 'EM metadata'     '_em_admin.current_status'          
19 15 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_PDB_obs_spr.id               OBSLTE 
_pdbx_database_PDB_obs_spr.date             2025-03-05 
_pdbx_database_PDB_obs_spr.pdb_id           NONE 
_pdbx_database_PDB_obs_spr.replace_pdb_id   8FG2 
_pdbx_database_PDB_obs_spr.details          'This entry has been made obsolete due to paper retraction' 
# 
_pdbx_database_status.status_code                     OBS 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8FG2 
_pdbx_database_status.recvd_initial_deposition_date   2022-12-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients' 
_pdbx_database_related.db_id          EMD-29072 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              Debkelly@psu.edu 
_pdbx_contact_author.name_first         Deb 
_pdbx_contact_author.name_last          Kelly 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7341-7435 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Casasanta, M.' 1 0000-0001-6614-9623 
'Jonaid, G.M.'  2 0000-0002-5694-2262 
'Kaylor, L.'    3 ?                   
'Luqiu, W.'     4 ?                   
'DiCecco, L.'   5 0000-0001-8420-1114 
'Solares, M.'   6 0000-0001-8388-7011 
'Berry, S.'     7 0000-0002-9537-312X 
'Kelly, D.F.'   8 0000-0002-7341-7435 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? US ? ? primary 'Microsc Microanal' ? ? 1435-8115 ? ? ?  ? ?    ?    
;Retraction of: Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
;
2025 ? 10.1093/mam/ozae127            39837351 ? ? 
? ? ? ? ? ? ? US ? ? 1       'Microsc Microanal' ? ? 1435-8115 ? ? ?  ? ?    ?    
'Structural insights of the SARS-CoV-2 Nucleocapsid protein: Implications for the inner-workings of rapid antigen tests' 2022 ? 
10.1093/micmic/ozac036/6957293 ?        ? ? 
? ? ? ? ? ? ? UK ? ? 2       Nanoscale           ? ? 2040-3372 ? ? 13 ? 7285 7293 
'Microchip-based structure determination of low-molecular weight proteins using cryo-electron microscopy.' 2021 ? 
10.1016/j.apsb.2020.04.009     33889923 ? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Casasanta, M.A.' 1  ?                   
primary 'Jonaid, G.M.'    2  ?                   
primary 'Kaylor, L.'      3  ?                   
primary 'Luqiu, W.Y.'     4  ?                   
primary 'DiCecco, L.A.'   5  ?                   
primary 'Solares, M.J.'   6  ?                   
primary 'Berry, S.'       7  ?                   
primary 'Dearnaley, W.J.' 8  ?                   
primary 'Kelly, D.F.'     9  ?                   
1       'Casasanta, M.'   10 0000-0001-6614-9623 
1       'Jonaid, G.M.'    11 0000-0002-5694-2262 
1       'Kaylor, L.'      12 ?                   
1       'Luqiu, W.'       13 ?                   
1       'DiCecco, L.'     14 0000-0001-8420-1114 
1       'Solares, M.'     15 0000-0001-8388-7011 
1       'Berry, S.'       16 0000-0002-9537-312X 
1       'Dearnaley, W.J.' 17 ?                   
1       'Kelly, D.F.'     18 0000-0002-7341-7435 
2       'Casasanta, M.A.' 19 ?                   
2       'Jonaid, G.M.'    20 ?                   
2       'Kaylor, L.'      21 ?                   
2       'Luqiu, W.Y.'     22 ?                   
2       'Solares, M.J.'   23 ?                   
2       'Schroen, M.L.'   24 ?                   
2       'Dearnaley, W.J.' 25 ?                   
2       'Wilson, J.'      26 ?                   
2       'Dukes, M.J.'     27 ?                   
2       'Kelly, D.F.'     28 ?                   
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 nat 
_entity.pdbx_description           Nucleoprotein 
_entity.formula_weight             45689.645 
_entity.pdbx_number_of_molecules   2 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'N,Nucleocapsid protein,NC,Protein N' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSP
DDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQ
LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQ
QQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRI
GMEVTPSGTWLTYTGAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADL
DDFSKQLQQSMSSADSTQA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSP
DDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQ
LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQ
QQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRI
GMEVTPSGTWLTYTGAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADL
DDFSKQLQQSMSSADSTQA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   ASP n 
1 4   ASN n 
1 5   GLY n 
1 6   PRO n 
1 7   GLN n 
1 8   ASN n 
1 9   GLN n 
1 10  ARG n 
1 11  ASN n 
1 12  ALA n 
1 13  PRO n 
1 14  ARG n 
1 15  ILE n 
1 16  THR n 
1 17  PHE n 
1 18  GLY n 
1 19  GLY n 
1 20  PRO n 
1 21  SER n 
1 22  ASP n 
1 23  SER n 
1 24  THR n 
1 25  GLY n 
1 26  SER n 
1 27  ASN n 
1 28  GLN n 
1 29  ASN n 
1 30  GLY n 
1 31  GLU n 
1 32  ARG n 
1 33  SER n 
1 34  GLY n 
1 35  ALA n 
1 36  ARG n 
1 37  SER n 
1 38  LYS n 
1 39  GLN n 
1 40  ARG n 
1 41  ARG n 
1 42  PRO n 
1 43  GLN n 
1 44  GLY n 
1 45  LEU n 
1 46  PRO n 
1 47  ASN n 
1 48  ASN n 
1 49  THR n 
1 50  ALA n 
1 51  SER n 
1 52  TRP n 
1 53  PHE n 
1 54  THR n 
1 55  ALA n 
1 56  LEU n 
1 57  THR n 
1 58  GLN n 
1 59  HIS n 
1 60  GLY n 
1 61  LYS n 
1 62  GLU n 
1 63  ASP n 
1 64  LEU n 
1 65  LYS n 
1 66  PHE n 
1 67  PRO n 
1 68  ARG n 
1 69  GLY n 
1 70  GLN n 
1 71  GLY n 
1 72  VAL n 
1 73  PRO n 
1 74  ILE n 
1 75  ASN n 
1 76  THR n 
1 77  ASN n 
1 78  SER n 
1 79  SER n 
1 80  PRO n 
1 81  ASP n 
1 82  ASP n 
1 83  GLN n 
1 84  ILE n 
1 85  GLY n 
1 86  TYR n 
1 87  TYR n 
1 88  ARG n 
1 89  ARG n 
1 90  ALA n 
1 91  THR n 
1 92  ARG n 
1 93  ARG n 
1 94  ILE n 
1 95  ARG n 
1 96  GLY n 
1 97  GLY n 
1 98  ASP n 
1 99  GLY n 
1 100 LYS n 
1 101 MET n 
1 102 LYS n 
1 103 ASP n 
1 104 LEU n 
1 105 SER n 
1 106 PRO n 
1 107 ARG n 
1 108 TRP n 
1 109 TYR n 
1 110 PHE n 
1 111 TYR n 
1 112 TYR n 
1 113 LEU n 
1 114 GLY n 
1 115 THR n 
1 116 GLY n 
1 117 PRO n 
1 118 GLU n 
1 119 ALA n 
1 120 GLY n 
1 121 LEU n 
1 122 PRO n 
1 123 TYR n 
1 124 GLY n 
1 125 ALA n 
1 126 ASN n 
1 127 LYS n 
1 128 ASP n 
1 129 GLY n 
1 130 ILE n 
1 131 ILE n 
1 132 TRP n 
1 133 VAL n 
1 134 ALA n 
1 135 THR n 
1 136 GLU n 
1 137 GLY n 
1 138 ALA n 
1 139 LEU n 
1 140 ASN n 
1 141 THR n 
1 142 PRO n 
1 143 LYS n 
1 144 ASP n 
1 145 HIS n 
1 146 ILE n 
1 147 GLY n 
1 148 THR n 
1 149 ARG n 
1 150 ASN n 
1 151 PRO n 
1 152 ALA n 
1 153 ASN n 
1 154 ASN n 
1 155 ALA n 
1 156 ALA n 
1 157 ILE n 
1 158 VAL n 
1 159 LEU n 
1 160 GLN n 
1 161 LEU n 
1 162 PRO n 
1 163 GLN n 
1 164 GLY n 
1 165 THR n 
1 166 THR n 
1 167 LEU n 
1 168 PRO n 
1 169 LYS n 
1 170 GLY n 
1 171 PHE n 
1 172 TYR n 
1 173 ALA n 
1 174 GLU n 
1 175 GLY n 
1 176 SER n 
1 177 ARG n 
1 178 GLY n 
1 179 GLY n 
1 180 SER n 
1 181 GLN n 
1 182 ALA n 
1 183 SER n 
1 184 SER n 
1 185 ARG n 
1 186 SER n 
1 187 SER n 
1 188 SER n 
1 189 ARG n 
1 190 SER n 
1 191 ARG n 
1 192 ASN n 
1 193 SER n 
1 194 SER n 
1 195 ARG n 
1 196 ASN n 
1 197 SER n 
1 198 THR n 
1 199 PRO n 
1 200 GLY n 
1 201 SER n 
1 202 SER n 
1 203 ARG n 
1 204 GLY n 
1 205 THR n 
1 206 SER n 
1 207 PRO n 
1 208 ALA n 
1 209 ARG n 
1 210 MET n 
1 211 ALA n 
1 212 GLY n 
1 213 ASN n 
1 214 GLY n 
1 215 GLY n 
1 216 ASP n 
1 217 ALA n 
1 218 ALA n 
1 219 LEU n 
1 220 ALA n 
1 221 LEU n 
1 222 LEU n 
1 223 LEU n 
1 224 LEU n 
1 225 ASP n 
1 226 ARG n 
1 227 LEU n 
1 228 ASN n 
1 229 GLN n 
1 230 LEU n 
1 231 GLU n 
1 232 SER n 
1 233 LYS n 
1 234 MET n 
1 235 SER n 
1 236 GLY n 
1 237 LYS n 
1 238 GLY n 
1 239 GLN n 
1 240 GLN n 
1 241 GLN n 
1 242 GLN n 
1 243 GLY n 
1 244 GLN n 
1 245 THR n 
1 246 VAL n 
1 247 THR n 
1 248 LYS n 
1 249 LYS n 
1 250 SER n 
1 251 ALA n 
1 252 ALA n 
1 253 GLU n 
1 254 ALA n 
1 255 SER n 
1 256 LYS n 
1 257 LYS n 
1 258 PRO n 
1 259 ARG n 
1 260 GLN n 
1 261 LYS n 
1 262 ARG n 
1 263 THR n 
1 264 ALA n 
1 265 THR n 
1 266 LYS n 
1 267 ALA n 
1 268 TYR n 
1 269 ASN n 
1 270 VAL n 
1 271 THR n 
1 272 GLN n 
1 273 ALA n 
1 274 PHE n 
1 275 GLY n 
1 276 ARG n 
1 277 ARG n 
1 278 GLY n 
1 279 PRO n 
1 280 GLU n 
1 281 GLN n 
1 282 THR n 
1 283 GLN n 
1 284 GLY n 
1 285 ASN n 
1 286 PHE n 
1 287 GLY n 
1 288 ASP n 
1 289 GLN n 
1 290 GLU n 
1 291 LEU n 
1 292 ILE n 
1 293 ARG n 
1 294 GLN n 
1 295 GLY n 
1 296 THR n 
1 297 ASP n 
1 298 TYR n 
1 299 LYS n 
1 300 HIS n 
1 301 TRP n 
1 302 PRO n 
1 303 GLN n 
1 304 ILE n 
1 305 ALA n 
1 306 GLN n 
1 307 PHE n 
1 308 ALA n 
1 309 PRO n 
1 310 SER n 
1 311 ALA n 
1 312 SER n 
1 313 ALA n 
1 314 PHE n 
1 315 PHE n 
1 316 GLY n 
1 317 MET n 
1 318 SER n 
1 319 ARG n 
1 320 ILE n 
1 321 GLY n 
1 322 MET n 
1 323 GLU n 
1 324 VAL n 
1 325 THR n 
1 326 PRO n 
1 327 SER n 
1 328 GLY n 
1 329 THR n 
1 330 TRP n 
1 331 LEU n 
1 332 THR n 
1 333 TYR n 
1 334 THR n 
1 335 GLY n 
1 336 ALA n 
1 337 ILE n 
1 338 LYS n 
1 339 LEU n 
1 340 ASP n 
1 341 ASP n 
1 342 LYS n 
1 343 ASP n 
1 344 PRO n 
1 345 ASN n 
1 346 PHE n 
1 347 LYS n 
1 348 ASP n 
1 349 GLN n 
1 350 VAL n 
1 351 ILE n 
1 352 LEU n 
1 353 LEU n 
1 354 ASN n 
1 355 LYS n 
1 356 HIS n 
1 357 ILE n 
1 358 ASP n 
1 359 ALA n 
1 360 TYR n 
1 361 LYS n 
1 362 THR n 
1 363 PHE n 
1 364 PRO n 
1 365 PRO n 
1 366 THR n 
1 367 GLU n 
1 368 PRO n 
1 369 LYS n 
1 370 LYS n 
1 371 ASP n 
1 372 LYS n 
1 373 LYS n 
1 374 LYS n 
1 375 LYS n 
1 376 ALA n 
1 377 ASP n 
1 378 GLU n 
1 379 THR n 
1 380 GLN n 
1 381 ALA n 
1 382 LEU n 
1 383 PRO n 
1 384 GLN n 
1 385 ARG n 
1 386 GLN n 
1 387 LYS n 
1 388 LYS n 
1 389 GLN n 
1 390 GLN n 
1 391 THR n 
1 392 VAL n 
1 393 THR n 
1 394 LEU n 
1 395 LEU n 
1 396 PRO n 
1 397 ALA n 
1 398 ALA n 
1 399 ASP n 
1 400 LEU n 
1 401 ASP n 
1 402 ASP n 
1 403 PHE n 
1 404 SER n 
1 405 LYS n 
1 406 GLN n 
1 407 LEU n 
1 408 GLN n 
1 409 GLN n 
1 410 SER n 
1 411 MET n 
1 412 SER n 
1 413 SER n 
1 414 ALA n 
1 415 ASP n 
1 416 SER n 
1 417 THR n 
1 418 GLN n 
1 419 ALA n 
# 
_entity_src_nat.entity_id                  1 
_entity_src_nat.pdbx_src_id                1 
_entity_src_nat.pdbx_alt_source_flag       sample 
_entity_src_nat.pdbx_beg_seq_num           1 
_entity_src_nat.pdbx_end_seq_num           419 
_entity_src_nat.common_name                human 
_entity_src_nat.pdbx_organism_scientific   'Homo sapiens' 
_entity_src_nat.pdbx_ncbi_taxonomy_id      9606 
_entity_src_nat.genus                      ? 
_entity_src_nat.species                    ? 
_entity_src_nat.strain                     ? 
_entity_src_nat.tissue                     ? 
_entity_src_nat.tissue_fraction            ? 
_entity_src_nat.pdbx_secretion             ? 
_entity_src_nat.pdbx_fragment              ? 
_entity_src_nat.pdbx_variant               ? 
_entity_src_nat.pdbx_cell_line             ? 
_entity_src_nat.pdbx_atcc                  ? 
_entity_src_nat.pdbx_cellular_location     ? 
_entity_src_nat.pdbx_organ                 ? 
_entity_src_nat.pdbx_organelle             ? 
_entity_src_nat.pdbx_cell                  ? 
_entity_src_nat.pdbx_plasmid_name          ? 
_entity_src_nat.pdbx_plasmid_details       ? 
_entity_src_nat.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   SER 2   2   2   SER SER A . n 
A 1 3   ASP 3   3   3   ASP ASP A . n 
A 1 4   ASN 4   4   4   ASN ASN A . n 
A 1 5   GLY 5   5   5   GLY GLY A . n 
A 1 6   PRO 6   6   6   PRO PRO A . n 
A 1 7   GLN 7   7   7   GLN GLN A . n 
A 1 8   ASN 8   8   8   ASN ASN A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  ARG 10  10  10  ARG ARG A . n 
A 1 11  ASN 11  11  11  ASN ASN A . n 
A 1 12  ALA 12  12  12  ALA ALA A . n 
A 1 13  PRO 13  13  13  PRO PRO A . n 
A 1 14  ARG 14  14  14  ARG ARG A . n 
A 1 15  ILE 15  15  15  ILE ILE A . n 
A 1 16  THR 16  16  16  THR THR A . n 
A 1 17  PHE 17  17  17  PHE PHE A . n 
A 1 18  GLY 18  18  18  GLY GLY A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  PRO 20  20  20  PRO PRO A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  ASP 22  22  22  ASP ASP A . n 
A 1 23  SER 23  23  23  SER SER A . n 
A 1 24  THR 24  24  24  THR THR A . n 
A 1 25  GLY 25  25  25  GLY GLY A . n 
A 1 26  SER 26  26  26  SER SER A . n 
A 1 27  ASN 27  27  27  ASN ASN A . n 
A 1 28  GLN 28  28  28  GLN GLN A . n 
A 1 29  ASN 29  29  29  ASN ASN A . n 
A 1 30  GLY 30  30  30  GLY GLY A . n 
A 1 31  GLU 31  31  31  GLU GLU A . n 
A 1 32  ARG 32  32  32  ARG ARG A . n 
A 1 33  SER 33  33  33  SER SER A . n 
A 1 34  GLY 34  34  34  GLY GLY A . n 
A 1 35  ALA 35  35  35  ALA ALA A . n 
A 1 36  ARG 36  36  36  ARG ARG A . n 
A 1 37  SER 37  37  37  SER SER A . n 
A 1 38  LYS 38  38  38  LYS LYS A . n 
A 1 39  GLN 39  39  39  GLN GLN A . n 
A 1 40  ARG 40  40  40  ARG ARG A . n 
A 1 41  ARG 41  41  41  ARG ARG A . n 
A 1 42  PRO 42  42  42  PRO PRO A . n 
A 1 43  GLN 43  43  43  GLN GLN A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  PRO 46  46  46  PRO PRO A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  ASN 48  48  48  ASN ASN A . n 
A 1 49  THR 49  49  49  THR THR A . n 
A 1 50  ALA 50  50  50  ALA ALA A . n 
A 1 51  SER 51  51  51  SER SER A . n 
A 1 52  TRP 52  52  52  TRP TRP A . n 
A 1 53  PHE 53  53  53  PHE PHE A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  LEU 56  56  56  LEU LEU A . n 
A 1 57  THR 57  57  57  THR THR A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  HIS 59  59  59  HIS HIS A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  GLU 62  62  62  GLU GLU A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  LYS 65  65  65  LYS LYS A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  PRO 67  67  67  PRO PRO A . n 
A 1 68  ARG 68  68  68  ARG ARG A . n 
A 1 69  GLY 69  69  69  GLY GLY A . n 
A 1 70  GLN 70  70  70  GLN GLN A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  PRO 73  73  73  PRO PRO A . n 
A 1 74  ILE 74  74  74  ILE ILE A . n 
A 1 75  ASN 75  75  75  ASN ASN A . n 
A 1 76  THR 76  76  76  THR THR A . n 
A 1 77  ASN 77  77  77  ASN ASN A . n 
A 1 78  SER 78  78  78  SER SER A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  PRO 80  80  80  PRO PRO A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  ASP 82  82  82  ASP ASP A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ILE 84  84  84  ILE ILE A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  TYR 86  86  86  TYR TYR A . n 
A 1 87  TYR 87  87  87  TYR TYR A . n 
A 1 88  ARG 88  88  88  ARG ARG A . n 
A 1 89  ARG 89  89  89  ARG ARG A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  ARG 92  92  92  ARG ARG A . n 
A 1 93  ARG 93  93  93  ARG ARG A . n 
A 1 94  ILE 94  94  94  ILE ILE A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  GLY 97  97  97  GLY GLY A . n 
A 1 98  ASP 98  98  98  ASP ASP A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 LYS 100 100 100 LYS LYS A . n 
A 1 101 MET 101 101 101 MET MET A . n 
A 1 102 LYS 102 102 102 LYS LYS A . n 
A 1 103 ASP 103 103 103 ASP ASP A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 SER 105 105 105 SER SER A . n 
A 1 106 PRO 106 106 106 PRO PRO A . n 
A 1 107 ARG 107 107 107 ARG ARG A . n 
A 1 108 TRP 108 108 108 TRP TRP A . n 
A 1 109 TYR 109 109 109 TYR TYR A . n 
A 1 110 PHE 110 110 110 PHE PHE A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 TYR 112 112 112 TYR TYR A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 PRO 117 117 117 PRO PRO A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 TYR 123 123 123 TYR TYR A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 ALA 125 125 125 ALA ALA A . n 
A 1 126 ASN 126 126 126 ASN ASN A . n 
A 1 127 LYS 127 127 127 LYS LYS A . n 
A 1 128 ASP 128 128 128 ASP ASP A . n 
A 1 129 GLY 129 129 129 GLY GLY A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 ILE 131 131 131 ILE ILE A . n 
A 1 132 TRP 132 132 132 TRP TRP A . n 
A 1 133 VAL 133 133 133 VAL VAL A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 LEU 139 139 139 LEU LEU A . n 
A 1 140 ASN 140 140 140 ASN ASN A . n 
A 1 141 THR 141 141 141 THR THR A . n 
A 1 142 PRO 142 142 142 PRO PRO A . n 
A 1 143 LYS 143 143 143 LYS LYS A . n 
A 1 144 ASP 144 144 144 ASP ASP A . n 
A 1 145 HIS 145 145 145 HIS HIS A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 THR 148 148 148 THR THR A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 ASN 150 150 150 ASN ASN A . n 
A 1 151 PRO 151 151 151 PRO PRO A . n 
A 1 152 ALA 152 152 152 ALA ALA A . n 
A 1 153 ASN 153 153 153 ASN ASN A . n 
A 1 154 ASN 154 154 154 ASN ASN A . n 
A 1 155 ALA 155 155 155 ALA ALA A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 ILE 157 157 157 ILE ILE A . n 
A 1 158 VAL 158 158 158 VAL VAL A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 GLN 160 160 160 GLN GLN A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 PRO 162 162 162 PRO PRO A . n 
A 1 163 GLN 163 163 163 GLN GLN A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 THR 165 165 165 THR THR A . n 
A 1 166 THR 166 166 166 THR THR A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 LYS 169 169 169 LYS LYS A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 PHE 171 171 171 PHE PHE A . n 
A 1 172 TYR 172 172 172 TYR TYR A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 GLY 175 175 175 GLY GLY A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 ARG 177 177 177 ARG ARG A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 SER 180 180 180 SER SER A . n 
A 1 181 GLN 181 181 181 GLN GLN A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 SER 184 184 184 SER SER A . n 
A 1 185 ARG 185 185 185 ARG ARG A . n 
A 1 186 SER 186 186 186 SER SER A . n 
A 1 187 SER 187 187 187 SER SER A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 ARG 189 189 189 ARG ARG A . n 
A 1 190 SER 190 190 190 SER SER A . n 
A 1 191 ARG 191 191 191 ARG ARG A . n 
A 1 192 ASN 192 192 192 ASN ASN A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 SER 194 194 194 SER SER A . n 
A 1 195 ARG 195 195 195 ARG ARG A . n 
A 1 196 ASN 196 196 196 ASN ASN A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 PRO 199 199 199 PRO PRO A . n 
A 1 200 GLY 200 200 200 GLY GLY A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 SER 202 202 202 SER SER A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 GLY 204 204 204 GLY GLY A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 SER 206 206 206 SER SER A . n 
A 1 207 PRO 207 207 207 PRO PRO A . n 
A 1 208 ALA 208 208 208 ALA ALA A . n 
A 1 209 ARG 209 209 209 ARG ARG A . n 
A 1 210 MET 210 210 210 MET MET A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 GLY 212 212 212 GLY GLY A . n 
A 1 213 ASN 213 213 213 ASN ASN A . n 
A 1 214 GLY 214 214 214 GLY GLY A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 ALA 217 217 217 ALA ALA A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 ALA 220 220 220 ALA ALA A . n 
A 1 221 LEU 221 221 221 LEU LEU A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 ASP 225 225 225 ASP ASP A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 ASN 228 228 228 ASN ASN A . n 
A 1 229 GLN 229 229 229 GLN GLN A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 GLU 231 231 231 GLU GLU A . n 
A 1 232 SER 232 232 232 SER SER A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 MET 234 234 234 MET MET A . n 
A 1 235 SER 235 235 235 SER SER A . n 
A 1 236 GLY 236 236 236 GLY GLY A . n 
A 1 237 LYS 237 237 237 LYS LYS A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 GLN 239 239 239 GLN GLN A . n 
A 1 240 GLN 240 240 240 GLN GLN A . n 
A 1 241 GLN 241 241 241 GLN GLN A . n 
A 1 242 GLN 242 242 242 GLN GLN A . n 
A 1 243 GLY 243 243 243 GLY GLY A . n 
A 1 244 GLN 244 244 244 GLN GLN A . n 
A 1 245 THR 245 245 245 THR THR A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 LYS 249 249 249 LYS LYS A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 GLU 253 253 253 GLU GLU A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 SER 255 255 255 SER SER A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 LYS 257 257 257 LYS LYS A . n 
A 1 258 PRO 258 258 258 PRO PRO A . n 
A 1 259 ARG 259 259 259 ARG ARG A . n 
A 1 260 GLN 260 260 260 GLN GLN A . n 
A 1 261 LYS 261 261 261 LYS LYS A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 THR 263 263 263 THR THR A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 THR 265 265 265 THR THR A . n 
A 1 266 LYS 266 266 266 LYS LYS A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 TYR 268 268 268 TYR TYR A . n 
A 1 269 ASN 269 269 269 ASN ASN A . n 
A 1 270 VAL 270 270 270 VAL VAL A . n 
A 1 271 THR 271 271 271 THR THR A . n 
A 1 272 GLN 272 272 272 GLN GLN A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 PHE 274 274 274 PHE PHE A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 ARG 277 277 277 ARG ARG A . n 
A 1 278 GLY 278 278 278 GLY GLY A . n 
A 1 279 PRO 279 279 279 PRO PRO A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 GLN 281 281 281 GLN GLN A . n 
A 1 282 THR 282 282 282 THR THR A . n 
A 1 283 GLN 283 283 283 GLN GLN A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 ASN 285 285 285 ASN ASN A . n 
A 1 286 PHE 286 286 286 PHE PHE A . n 
A 1 287 GLY 287 287 287 GLY GLY A . n 
A 1 288 ASP 288 288 288 ASP ASP A . n 
A 1 289 GLN 289 289 289 GLN GLN A . n 
A 1 290 GLU 290 290 290 GLU GLU A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 ILE 292 292 292 ILE ILE A . n 
A 1 293 ARG 293 293 293 ARG ARG A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 ASP 297 297 297 ASP ASP A . n 
A 1 298 TYR 298 298 298 TYR TYR A . n 
A 1 299 LYS 299 299 299 LYS LYS A . n 
A 1 300 HIS 300 300 300 HIS HIS A . n 
A 1 301 TRP 301 301 301 TRP TRP A . n 
A 1 302 PRO 302 302 302 PRO PRO A . n 
A 1 303 GLN 303 303 303 GLN GLN A . n 
A 1 304 ILE 304 304 304 ILE ILE A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 GLN 306 306 306 GLN GLN A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 PRO 309 309 309 PRO PRO A . n 
A 1 310 SER 310 310 310 SER SER A . n 
A 1 311 ALA 311 311 311 ALA ALA A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 PHE 314 314 314 PHE PHE A . n 
A 1 315 PHE 315 315 315 PHE PHE A . n 
A 1 316 GLY 316 316 316 GLY GLY A . n 
A 1 317 MET 317 317 317 MET MET A . n 
A 1 318 SER 318 318 318 SER SER A . n 
A 1 319 ARG 319 319 319 ARG ARG A . n 
A 1 320 ILE 320 320 320 ILE ILE A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 MET 322 322 322 MET MET A . n 
A 1 323 GLU 323 323 323 GLU GLU A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 GLY 328 328 328 GLY GLY A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 TRP 330 330 330 TRP TRP A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 THR 332 332 332 THR THR A . n 
A 1 333 TYR 333 333 333 TYR TYR A . n 
A 1 334 THR 334 334 334 THR THR A . n 
A 1 335 GLY 335 335 335 GLY GLY A . n 
A 1 336 ALA 336 336 336 ALA ALA A . n 
A 1 337 ILE 337 337 337 ILE ILE A . n 
A 1 338 LYS 338 338 338 LYS LYS A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 ASP 341 341 341 ASP ASP A . n 
A 1 342 LYS 342 342 342 LYS LYS A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 PRO 344 344 344 PRO PRO A . n 
A 1 345 ASN 345 345 345 ASN ASN A . n 
A 1 346 PHE 346 346 346 PHE PHE A . n 
A 1 347 LYS 347 347 347 LYS LYS A . n 
A 1 348 ASP 348 348 348 ASP ASP A . n 
A 1 349 GLN 349 349 349 GLN GLN A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 ILE 351 351 351 ILE ILE A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 ASN 354 354 354 ASN ASN A . n 
A 1 355 LYS 355 355 355 LYS LYS A . n 
A 1 356 HIS 356 356 356 HIS HIS A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 ASP 358 358 358 ASP ASP A . n 
A 1 359 ALA 359 359 359 ALA ALA A . n 
A 1 360 TYR 360 360 360 TYR TYR A . n 
A 1 361 LYS 361 361 361 LYS LYS A . n 
A 1 362 THR 362 362 362 THR THR A . n 
A 1 363 PHE 363 363 363 PHE PHE A . n 
A 1 364 PRO 364 364 364 PRO PRO A . n 
A 1 365 PRO 365 365 365 PRO PRO A . n 
A 1 366 THR 366 366 366 THR THR A . n 
A 1 367 GLU 367 367 367 GLU GLU A . n 
A 1 368 PRO 368 368 368 PRO PRO A . n 
A 1 369 LYS 369 369 369 LYS LYS A . n 
A 1 370 LYS 370 370 370 LYS LYS A . n 
A 1 371 ASP 371 371 371 ASP ASP A . n 
A 1 372 LYS 372 372 372 LYS LYS A . n 
A 1 373 LYS 373 373 373 LYS LYS A . n 
A 1 374 LYS 374 374 374 LYS LYS A . n 
A 1 375 LYS 375 375 375 LYS LYS A . n 
A 1 376 ALA 376 376 376 ALA ALA A . n 
A 1 377 ASP 377 377 377 ASP ASP A . n 
A 1 378 GLU 378 378 378 GLU GLU A . n 
A 1 379 THR 379 379 379 THR THR A . n 
A 1 380 GLN 380 380 380 GLN GLN A . n 
A 1 381 ALA 381 381 381 ALA ALA A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 PRO 383 383 383 PRO PRO A . n 
A 1 384 GLN 384 384 384 GLN GLN A . n 
A 1 385 ARG 385 385 385 ARG ARG A . n 
A 1 386 GLN 386 386 386 GLN GLN A . n 
A 1 387 LYS 387 387 387 LYS LYS A . n 
A 1 388 LYS 388 388 388 LYS LYS A . n 
A 1 389 GLN 389 389 389 GLN GLN A . n 
A 1 390 GLN 390 390 390 GLN GLN A . n 
A 1 391 THR 391 391 391 THR THR A . n 
A 1 392 VAL 392 392 392 VAL VAL A . n 
A 1 393 THR 393 393 393 THR THR A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 LEU 395 395 395 LEU LEU A . n 
A 1 396 PRO 396 396 396 PRO PRO A . n 
A 1 397 ALA 397 397 397 ALA ALA A . n 
A 1 398 ALA 398 398 398 ALA ALA A . n 
A 1 399 ASP 399 399 399 ASP ASP A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 ASP 401 401 401 ASP ASP A . n 
A 1 402 ASP 402 402 402 ASP ASP A . n 
A 1 403 PHE 403 403 403 PHE PHE A . n 
A 1 404 SER 404 404 404 SER SER A . n 
A 1 405 LYS 405 405 405 LYS LYS A . n 
A 1 406 GLN 406 406 406 GLN GLN A . n 
A 1 407 LEU 407 407 407 LEU LEU A . n 
A 1 408 GLN 408 408 408 GLN GLN A . n 
A 1 409 GLN 409 409 409 GLN GLN A . n 
A 1 410 SER 410 410 410 SER SER A . n 
A 1 411 MET 411 411 411 MET MET A . n 
A 1 412 SER 412 412 412 SER SER A . n 
A 1 413 SER 413 413 413 SER SER A . n 
A 1 414 ALA 414 414 414 ALA ALA A . n 
A 1 415 ASP 415 415 415 ASP ASP A . n 
A 1 416 SER 416 416 416 SER SER A . n 
A 1 417 THR 417 417 417 THR THR A . n 
A 1 418 GLN 418 418 418 GLN GLN A . n 
A 1 419 ALA 419 419 419 ALA ALA A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   SER 2   2   2   SER SER B . n 
B 1 3   ASP 3   3   3   ASP ASP B . n 
B 1 4   ASN 4   4   4   ASN ASN B . n 
B 1 5   GLY 5   5   5   GLY GLY B . n 
B 1 6   PRO 6   6   6   PRO PRO B . n 
B 1 7   GLN 7   7   7   GLN GLN B . n 
B 1 8   ASN 8   8   8   ASN ASN B . n 
B 1 9   GLN 9   9   9   GLN GLN B . n 
B 1 10  ARG 10  10  10  ARG ARG B . n 
B 1 11  ASN 11  11  11  ASN ASN B . n 
B 1 12  ALA 12  12  12  ALA ALA B . n 
B 1 13  PRO 13  13  13  PRO PRO B . n 
B 1 14  ARG 14  14  14  ARG ARG B . n 
B 1 15  ILE 15  15  15  ILE ILE B . n 
B 1 16  THR 16  16  16  THR THR B . n 
B 1 17  PHE 17  17  17  PHE PHE B . n 
B 1 18  GLY 18  18  18  GLY GLY B . n 
B 1 19  GLY 19  19  19  GLY GLY B . n 
B 1 20  PRO 20  20  20  PRO PRO B . n 
B 1 21  SER 21  21  21  SER SER B . n 
B 1 22  ASP 22  22  22  ASP ASP B . n 
B 1 23  SER 23  23  23  SER SER B . n 
B 1 24  THR 24  24  24  THR THR B . n 
B 1 25  GLY 25  25  25  GLY GLY B . n 
B 1 26  SER 26  26  26  SER SER B . n 
B 1 27  ASN 27  27  27  ASN ASN B . n 
B 1 28  GLN 28  28  28  GLN GLN B . n 
B 1 29  ASN 29  29  29  ASN ASN B . n 
B 1 30  GLY 30  30  30  GLY GLY B . n 
B 1 31  GLU 31  31  31  GLU GLU B . n 
B 1 32  ARG 32  32  32  ARG ARG B . n 
B 1 33  SER 33  33  33  SER SER B . n 
B 1 34  GLY 34  34  34  GLY GLY B . n 
B 1 35  ALA 35  35  35  ALA ALA B . n 
B 1 36  ARG 36  36  36  ARG ARG B . n 
B 1 37  SER 37  37  37  SER SER B . n 
B 1 38  LYS 38  38  38  LYS LYS B . n 
B 1 39  GLN 39  39  39  GLN GLN B . n 
B 1 40  ARG 40  40  40  ARG ARG B . n 
B 1 41  ARG 41  41  41  ARG ARG B . n 
B 1 42  PRO 42  42  42  PRO PRO B . n 
B 1 43  GLN 43  43  43  GLN GLN B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  LEU 45  45  45  LEU LEU B . n 
B 1 46  PRO 46  46  46  PRO PRO B . n 
B 1 47  ASN 47  47  47  ASN ASN B . n 
B 1 48  ASN 48  48  48  ASN ASN B . n 
B 1 49  THR 49  49  49  THR THR B . n 
B 1 50  ALA 50  50  50  ALA ALA B . n 
B 1 51  SER 51  51  51  SER SER B . n 
B 1 52  TRP 52  52  52  TRP TRP B . n 
B 1 53  PHE 53  53  53  PHE PHE B . n 
B 1 54  THR 54  54  54  THR THR B . n 
B 1 55  ALA 55  55  55  ALA ALA B . n 
B 1 56  LEU 56  56  56  LEU LEU B . n 
B 1 57  THR 57  57  57  THR THR B . n 
B 1 58  GLN 58  58  58  GLN GLN B . n 
B 1 59  HIS 59  59  59  HIS HIS B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  GLU 62  62  62  GLU GLU B . n 
B 1 63  ASP 63  63  63  ASP ASP B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  LYS 65  65  65  LYS LYS B . n 
B 1 66  PHE 66  66  66  PHE PHE B . n 
B 1 67  PRO 67  67  67  PRO PRO B . n 
B 1 68  ARG 68  68  68  ARG ARG B . n 
B 1 69  GLY 69  69  69  GLY GLY B . n 
B 1 70  GLN 70  70  70  GLN GLN B . n 
B 1 71  GLY 71  71  71  GLY GLY B . n 
B 1 72  VAL 72  72  72  VAL VAL B . n 
B 1 73  PRO 73  73  73  PRO PRO B . n 
B 1 74  ILE 74  74  74  ILE ILE B . n 
B 1 75  ASN 75  75  75  ASN ASN B . n 
B 1 76  THR 76  76  76  THR THR B . n 
B 1 77  ASN 77  77  77  ASN ASN B . n 
B 1 78  SER 78  78  78  SER SER B . n 
B 1 79  SER 79  79  79  SER SER B . n 
B 1 80  PRO 80  80  80  PRO PRO B . n 
B 1 81  ASP 81  81  81  ASP ASP B . n 
B 1 82  ASP 82  82  82  ASP ASP B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ILE 84  84  84  ILE ILE B . n 
B 1 85  GLY 85  85  85  GLY GLY B . n 
B 1 86  TYR 86  86  86  TYR TYR B . n 
B 1 87  TYR 87  87  87  TYR TYR B . n 
B 1 88  ARG 88  88  88  ARG ARG B . n 
B 1 89  ARG 89  89  89  ARG ARG B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  THR 91  91  91  THR THR B . n 
B 1 92  ARG 92  92  92  ARG ARG B . n 
B 1 93  ARG 93  93  93  ARG ARG B . n 
B 1 94  ILE 94  94  94  ILE ILE B . n 
B 1 95  ARG 95  95  95  ARG ARG B . n 
B 1 96  GLY 96  96  96  GLY GLY B . n 
B 1 97  GLY 97  97  97  GLY GLY B . n 
B 1 98  ASP 98  98  98  ASP ASP B . n 
B 1 99  GLY 99  99  99  GLY GLY B . n 
B 1 100 LYS 100 100 100 LYS LYS B . n 
B 1 101 MET 101 101 101 MET MET B . n 
B 1 102 LYS 102 102 102 LYS LYS B . n 
B 1 103 ASP 103 103 103 ASP ASP B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 SER 105 105 105 SER SER B . n 
B 1 106 PRO 106 106 106 PRO PRO B . n 
B 1 107 ARG 107 107 107 ARG ARG B . n 
B 1 108 TRP 108 108 108 TRP TRP B . n 
B 1 109 TYR 109 109 109 TYR TYR B . n 
B 1 110 PHE 110 110 110 PHE PHE B . n 
B 1 111 TYR 111 111 111 TYR TYR B . n 
B 1 112 TYR 112 112 112 TYR TYR B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 THR 115 115 115 THR THR B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 PRO 117 117 117 PRO PRO B . n 
B 1 118 GLU 118 118 118 GLU GLU B . n 
B 1 119 ALA 119 119 119 ALA ALA B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 TYR 123 123 123 TYR TYR B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 ALA 125 125 125 ALA ALA B . n 
B 1 126 ASN 126 126 126 ASN ASN B . n 
B 1 127 LYS 127 127 127 LYS LYS B . n 
B 1 128 ASP 128 128 128 ASP ASP B . n 
B 1 129 GLY 129 129 129 GLY GLY B . n 
B 1 130 ILE 130 130 130 ILE ILE B . n 
B 1 131 ILE 131 131 131 ILE ILE B . n 
B 1 132 TRP 132 132 132 TRP TRP B . n 
B 1 133 VAL 133 133 133 VAL VAL B . n 
B 1 134 ALA 134 134 134 ALA ALA B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 LEU 139 139 139 LEU LEU B . n 
B 1 140 ASN 140 140 140 ASN ASN B . n 
B 1 141 THR 141 141 141 THR THR B . n 
B 1 142 PRO 142 142 142 PRO PRO B . n 
B 1 143 LYS 143 143 143 LYS LYS B . n 
B 1 144 ASP 144 144 144 ASP ASP B . n 
B 1 145 HIS 145 145 145 HIS HIS B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 GLY 147 147 147 GLY GLY B . n 
B 1 148 THR 148 148 148 THR THR B . n 
B 1 149 ARG 149 149 149 ARG ARG B . n 
B 1 150 ASN 150 150 150 ASN ASN B . n 
B 1 151 PRO 151 151 151 PRO PRO B . n 
B 1 152 ALA 152 152 152 ALA ALA B . n 
B 1 153 ASN 153 153 153 ASN ASN B . n 
B 1 154 ASN 154 154 154 ASN ASN B . n 
B 1 155 ALA 155 155 155 ALA ALA B . n 
B 1 156 ALA 156 156 156 ALA ALA B . n 
B 1 157 ILE 157 157 157 ILE ILE B . n 
B 1 158 VAL 158 158 158 VAL VAL B . n 
B 1 159 LEU 159 159 159 LEU LEU B . n 
B 1 160 GLN 160 160 160 GLN GLN B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 PRO 162 162 162 PRO PRO B . n 
B 1 163 GLN 163 163 163 GLN GLN B . n 
B 1 164 GLY 164 164 164 GLY GLY B . n 
B 1 165 THR 165 165 165 THR THR B . n 
B 1 166 THR 166 166 166 THR THR B . n 
B 1 167 LEU 167 167 167 LEU LEU B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 LYS 169 169 169 LYS LYS B . n 
B 1 170 GLY 170 170 170 GLY GLY B . n 
B 1 171 PHE 171 171 171 PHE PHE B . n 
B 1 172 TYR 172 172 172 TYR TYR B . n 
B 1 173 ALA 173 173 173 ALA ALA B . n 
B 1 174 GLU 174 174 174 GLU GLU B . n 
B 1 175 GLY 175 175 175 GLY GLY B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 ARG 177 177 177 ARG ARG B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 GLY 179 179 179 GLY GLY B . n 
B 1 180 SER 180 180 180 SER SER B . n 
B 1 181 GLN 181 181 181 GLN GLN B . n 
B 1 182 ALA 182 182 182 ALA ALA B . n 
B 1 183 SER 183 183 183 SER SER B . n 
B 1 184 SER 184 184 184 SER SER B . n 
B 1 185 ARG 185 185 185 ARG ARG B . n 
B 1 186 SER 186 186 186 SER SER B . n 
B 1 187 SER 187 187 187 SER SER B . n 
B 1 188 SER 188 188 188 SER SER B . n 
B 1 189 ARG 189 189 189 ARG ARG B . n 
B 1 190 SER 190 190 190 SER SER B . n 
B 1 191 ARG 191 191 191 ARG ARG B . n 
B 1 192 ASN 192 192 192 ASN ASN B . n 
B 1 193 SER 193 193 193 SER SER B . n 
B 1 194 SER 194 194 194 SER SER B . n 
B 1 195 ARG 195 195 195 ARG ARG B . n 
B 1 196 ASN 196 196 196 ASN ASN B . n 
B 1 197 SER 197 197 197 SER SER B . n 
B 1 198 THR 198 198 198 THR THR B . n 
B 1 199 PRO 199 199 199 PRO PRO B . n 
B 1 200 GLY 200 200 200 GLY GLY B . n 
B 1 201 SER 201 201 201 SER SER B . n 
B 1 202 SER 202 202 202 SER SER B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 GLY 204 204 204 GLY GLY B . n 
B 1 205 THR 205 205 205 THR THR B . n 
B 1 206 SER 206 206 206 SER SER B . n 
B 1 207 PRO 207 207 207 PRO PRO B . n 
B 1 208 ALA 208 208 208 ALA ALA B . n 
B 1 209 ARG 209 209 209 ARG ARG B . n 
B 1 210 MET 210 210 210 MET MET B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 GLY 212 212 212 GLY GLY B . n 
B 1 213 ASN 213 213 213 ASN ASN B . n 
B 1 214 GLY 214 214 214 GLY GLY B . n 
B 1 215 GLY 215 215 215 GLY GLY B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 ALA 217 217 217 ALA ALA B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 LEU 219 219 219 LEU LEU B . n 
B 1 220 ALA 220 220 220 ALA ALA B . n 
B 1 221 LEU 221 221 221 LEU LEU B . n 
B 1 222 LEU 222 222 222 LEU LEU B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 LEU 224 224 224 LEU LEU B . n 
B 1 225 ASP 225 225 225 ASP ASP B . n 
B 1 226 ARG 226 226 226 ARG ARG B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 ASN 228 228 228 ASN ASN B . n 
B 1 229 GLN 229 229 229 GLN GLN B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 GLU 231 231 231 GLU GLU B . n 
B 1 232 SER 232 232 232 SER SER B . n 
B 1 233 LYS 233 233 233 LYS LYS B . n 
B 1 234 MET 234 234 234 MET MET B . n 
B 1 235 SER 235 235 235 SER SER B . n 
B 1 236 GLY 236 236 236 GLY GLY B . n 
B 1 237 LYS 237 237 237 LYS LYS B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 GLN 239 239 239 GLN GLN B . n 
B 1 240 GLN 240 240 240 GLN GLN B . n 
B 1 241 GLN 241 241 241 GLN GLN B . n 
B 1 242 GLN 242 242 242 GLN GLN B . n 
B 1 243 GLY 243 243 243 GLY GLY B . n 
B 1 244 GLN 244 244 244 GLN GLN B . n 
B 1 245 THR 245 245 245 THR THR B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 THR 247 247 247 THR THR B . n 
B 1 248 LYS 248 248 248 LYS LYS B . n 
B 1 249 LYS 249 249 249 LYS LYS B . n 
B 1 250 SER 250 250 250 SER SER B . n 
B 1 251 ALA 251 251 251 ALA ALA B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 GLU 253 253 253 GLU GLU B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 SER 255 255 255 SER SER B . n 
B 1 256 LYS 256 256 256 LYS LYS B . n 
B 1 257 LYS 257 257 257 LYS LYS B . n 
B 1 258 PRO 258 258 258 PRO PRO B . n 
B 1 259 ARG 259 259 259 ARG ARG B . n 
B 1 260 GLN 260 260 260 GLN GLN B . n 
B 1 261 LYS 261 261 261 LYS LYS B . n 
B 1 262 ARG 262 262 262 ARG ARG B . n 
B 1 263 THR 263 263 263 THR THR B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 THR 265 265 265 THR THR B . n 
B 1 266 LYS 266 266 266 LYS LYS B . n 
B 1 267 ALA 267 267 267 ALA ALA B . n 
B 1 268 TYR 268 268 268 TYR TYR B . n 
B 1 269 ASN 269 269 269 ASN ASN B . n 
B 1 270 VAL 270 270 270 VAL VAL B . n 
B 1 271 THR 271 271 271 THR THR B . n 
B 1 272 GLN 272 272 272 GLN GLN B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 PHE 274 274 274 PHE PHE B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 ARG 277 277 277 ARG ARG B . n 
B 1 278 GLY 278 278 278 GLY GLY B . n 
B 1 279 PRO 279 279 279 PRO PRO B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 GLN 281 281 281 GLN GLN B . n 
B 1 282 THR 282 282 282 THR THR B . n 
B 1 283 GLN 283 283 283 GLN GLN B . n 
B 1 284 GLY 284 284 284 GLY GLY B . n 
B 1 285 ASN 285 285 285 ASN ASN B . n 
B 1 286 PHE 286 286 286 PHE PHE B . n 
B 1 287 GLY 287 287 287 GLY GLY B . n 
B 1 288 ASP 288 288 288 ASP ASP B . n 
B 1 289 GLN 289 289 289 GLN GLN B . n 
B 1 290 GLU 290 290 290 GLU GLU B . n 
B 1 291 LEU 291 291 291 LEU LEU B . n 
B 1 292 ILE 292 292 292 ILE ILE B . n 
B 1 293 ARG 293 293 293 ARG ARG B . n 
B 1 294 GLN 294 294 294 GLN GLN B . n 
B 1 295 GLY 295 295 295 GLY GLY B . n 
B 1 296 THR 296 296 296 THR THR B . n 
B 1 297 ASP 297 297 297 ASP ASP B . n 
B 1 298 TYR 298 298 298 TYR TYR B . n 
B 1 299 LYS 299 299 299 LYS LYS B . n 
B 1 300 HIS 300 300 300 HIS HIS B . n 
B 1 301 TRP 301 301 301 TRP TRP B . n 
B 1 302 PRO 302 302 302 PRO PRO B . n 
B 1 303 GLN 303 303 303 GLN GLN B . n 
B 1 304 ILE 304 304 304 ILE ILE B . n 
B 1 305 ALA 305 305 305 ALA ALA B . n 
B 1 306 GLN 306 306 306 GLN GLN B . n 
B 1 307 PHE 307 307 307 PHE PHE B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 PRO 309 309 309 PRO PRO B . n 
B 1 310 SER 310 310 310 SER SER B . n 
B 1 311 ALA 311 311 311 ALA ALA B . n 
B 1 312 SER 312 312 312 SER SER B . n 
B 1 313 ALA 313 313 313 ALA ALA B . n 
B 1 314 PHE 314 314 314 PHE PHE B . n 
B 1 315 PHE 315 315 315 PHE PHE B . n 
B 1 316 GLY 316 316 316 GLY GLY B . n 
B 1 317 MET 317 317 317 MET MET B . n 
B 1 318 SER 318 318 318 SER SER B . n 
B 1 319 ARG 319 319 319 ARG ARG B . n 
B 1 320 ILE 320 320 320 ILE ILE B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 MET 322 322 322 MET MET B . n 
B 1 323 GLU 323 323 323 GLU GLU B . n 
B 1 324 VAL 324 324 324 VAL VAL B . n 
B 1 325 THR 325 325 325 THR THR B . n 
B 1 326 PRO 326 326 326 PRO PRO B . n 
B 1 327 SER 327 327 327 SER SER B . n 
B 1 328 GLY 328 328 328 GLY GLY B . n 
B 1 329 THR 329 329 329 THR THR B . n 
B 1 330 TRP 330 330 330 TRP TRP B . n 
B 1 331 LEU 331 331 331 LEU LEU B . n 
B 1 332 THR 332 332 332 THR THR B . n 
B 1 333 TYR 333 333 333 TYR TYR B . n 
B 1 334 THR 334 334 334 THR THR B . n 
B 1 335 GLY 335 335 335 GLY GLY B . n 
B 1 336 ALA 336 336 336 ALA ALA B . n 
B 1 337 ILE 337 337 337 ILE ILE B . n 
B 1 338 LYS 338 338 338 LYS LYS B . n 
B 1 339 LEU 339 339 339 LEU LEU B . n 
B 1 340 ASP 340 340 340 ASP ASP B . n 
B 1 341 ASP 341 341 341 ASP ASP B . n 
B 1 342 LYS 342 342 342 LYS LYS B . n 
B 1 343 ASP 343 343 343 ASP ASP B . n 
B 1 344 PRO 344 344 344 PRO PRO B . n 
B 1 345 ASN 345 345 345 ASN ASN B . n 
B 1 346 PHE 346 346 346 PHE PHE B . n 
B 1 347 LYS 347 347 347 LYS LYS B . n 
B 1 348 ASP 348 348 348 ASP ASP B . n 
B 1 349 GLN 349 349 349 GLN GLN B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 ILE 351 351 351 ILE ILE B . n 
B 1 352 LEU 352 352 352 LEU LEU B . n 
B 1 353 LEU 353 353 353 LEU LEU B . n 
B 1 354 ASN 354 354 354 ASN ASN B . n 
B 1 355 LYS 355 355 355 LYS LYS B . n 
B 1 356 HIS 356 356 356 HIS HIS B . n 
B 1 357 ILE 357 357 357 ILE ILE B . n 
B 1 358 ASP 358 358 358 ASP ASP B . n 
B 1 359 ALA 359 359 359 ALA ALA B . n 
B 1 360 TYR 360 360 360 TYR TYR B . n 
B 1 361 LYS 361 361 361 LYS LYS B . n 
B 1 362 THR 362 362 362 THR THR B . n 
B 1 363 PHE 363 363 363 PHE PHE B . n 
B 1 364 PRO 364 364 364 PRO PRO B . n 
B 1 365 PRO 365 365 365 PRO PRO B . n 
B 1 366 THR 366 366 366 THR THR B . n 
B 1 367 GLU 367 367 367 GLU GLU B . n 
B 1 368 PRO 368 368 368 PRO PRO B . n 
B 1 369 LYS 369 369 369 LYS LYS B . n 
B 1 370 LYS 370 370 370 LYS LYS B . n 
B 1 371 ASP 371 371 371 ASP ASP B . n 
B 1 372 LYS 372 372 372 LYS LYS B . n 
B 1 373 LYS 373 373 373 LYS LYS B . n 
B 1 374 LYS 374 374 374 LYS LYS B . n 
B 1 375 LYS 375 375 375 LYS LYS B . n 
B 1 376 ALA 376 376 376 ALA ALA B . n 
B 1 377 ASP 377 377 377 ASP ASP B . n 
B 1 378 GLU 378 378 378 GLU GLU B . n 
B 1 379 THR 379 379 379 THR THR B . n 
B 1 380 GLN 380 380 380 GLN GLN B . n 
B 1 381 ALA 381 381 381 ALA ALA B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 PRO 383 383 383 PRO PRO B . n 
B 1 384 GLN 384 384 384 GLN GLN B . n 
B 1 385 ARG 385 385 385 ARG ARG B . n 
B 1 386 GLN 386 386 386 GLN GLN B . n 
B 1 387 LYS 387 387 387 LYS LYS B . n 
B 1 388 LYS 388 388 388 LYS LYS B . n 
B 1 389 GLN 389 389 389 GLN GLN B . n 
B 1 390 GLN 390 390 390 GLN GLN B . n 
B 1 391 THR 391 391 391 THR THR B . n 
B 1 392 VAL 392 392 392 VAL VAL B . n 
B 1 393 THR 393 393 393 THR THR B . n 
B 1 394 LEU 394 394 394 LEU LEU B . n 
B 1 395 LEU 395 395 395 LEU LEU B . n 
B 1 396 PRO 396 396 396 PRO PRO B . n 
B 1 397 ALA 397 397 397 ALA ALA B . n 
B 1 398 ALA 398 398 398 ALA ALA B . n 
B 1 399 ASP 399 399 399 ASP ASP B . n 
B 1 400 LEU 400 400 400 LEU LEU B . n 
B 1 401 ASP 401 401 401 ASP ASP B . n 
B 1 402 ASP 402 402 402 ASP ASP B . n 
B 1 403 PHE 403 403 403 PHE PHE B . n 
B 1 404 SER 404 404 404 SER SER B . n 
B 1 405 LYS 405 405 405 LYS LYS B . n 
B 1 406 GLN 406 406 406 GLN GLN B . n 
B 1 407 LEU 407 407 407 LEU LEU B . n 
B 1 408 GLN 408 408 408 GLN GLN B . n 
B 1 409 GLN 409 409 409 GLN GLN B . n 
B 1 410 SER 410 410 410 SER SER B . n 
B 1 411 MET 411 411 411 MET MET B . n 
B 1 412 SER 412 412 412 SER SER B . n 
B 1 413 SER 413 413 413 SER SER B . n 
B 1 414 ALA 414 414 414 ALA ALA B . n 
B 1 415 ASP 415 415 415 ASP ASP B . n 
B 1 416 SER 416 416 416 SER SER B . n 
B 1 417 THR 417 417 417 THR THR B . n 
B 1 418 GLN 418 418 418 GLN GLN B . n 
B 1 419 ALA 419 419 419 ALA ALA B . n 
# 
_pdbx_unobs_or_zero_occ_atoms.id               1 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id     MET 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id      1 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id     N 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id     ? 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id    A 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id    MET 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id     1 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id    N 
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.17.1_3660: 
_software.pdbx_ordinal           1 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8FG2 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8FG2 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006  ? 3276 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.107  ? 4416 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 46.831 ? 456  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.057  ? 457  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.008  ? 599  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8FG2 
_struct.title                        'SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8FG2 
_struct_keywords.text            'SARS-CoV-2, N protein, COVID-19, RNA binding protein, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    NCAP_SARS2 
_struct_ref.pdbx_db_accession          P0DTC9 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSP
DDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQ
LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQ
QQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRI
GMEVTPSGTWLTYTGAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADL
DDFSKQLQQSMSSADSTQA
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8FG2 A 1 ? 419 ? P0DTC9 1 ? 419 ? 1 419 
2 1 8FG2 B 1 ? 419 ? P0DTC9 1 ? 419 ? 1 419 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'native gel electrophoresis' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 100 ? LEU A 104 ? LYS A 100 LEU A 104 5 ? 5  
HELX_P HELX_P2  AA2 LEU A 219 ? MET A 234 ? LEU A 219 MET A 234 1 ? 16 
HELX_P HELX_P3  AA3 ALA A 252 ? LYS A 257 ? ALA A 252 LYS A 257 5 ? 6  
HELX_P HELX_P4  AA4 PRO A 258 ? ARG A 262 ? PRO A 258 ARG A 262 5 ? 5  
HELX_P HELX_P5  AA5 ASN A 269 ? PHE A 274 ? ASN A 269 PHE A 274 1 ? 6  
HELX_P HELX_P6  AA6 ASP A 288 ? GLY A 295 ? ASP A 288 GLY A 295 1 ? 8  
HELX_P HELX_P7  AA7 HIS A 300 ? ALA A 305 ? HIS A 300 ALA A 305 1 ? 6  
HELX_P HELX_P8  AA8 SER A 310 ? PHE A 315 ? SER A 310 PHE A 315 1 ? 6  
HELX_P HELX_P9  AA9 ASN A 345 ? ILE A 357 ? ASN A 345 ILE A 357 1 ? 13 
HELX_P HELX_P10 AB1 ASP A 358 ? PHE A 363 ? ASP A 358 PHE A 363 5 ? 6  
HELX_P HELX_P11 AB2 ALA A 398 ? SER A 416 ? ALA A 398 SER A 416 1 ? 19 
HELX_P HELX_P12 AB3 LYS B 100 ? LEU B 104 ? LYS B 100 LEU B 104 5 ? 5  
HELX_P HELX_P13 AB4 LEU B 219 ? MET B 234 ? LEU B 219 MET B 234 1 ? 16 
HELX_P HELX_P14 AB5 ALA B 252 ? LYS B 257 ? ALA B 252 LYS B 257 5 ? 6  
HELX_P HELX_P15 AB6 PRO B 258 ? ARG B 262 ? PRO B 258 ARG B 262 5 ? 5  
HELX_P HELX_P16 AB7 ASN B 269 ? PHE B 274 ? ASN B 269 PHE B 274 1 ? 6  
HELX_P HELX_P17 AB8 ASP B 288 ? GLY B 295 ? ASP B 288 GLY B 295 1 ? 8  
HELX_P HELX_P18 AB9 HIS B 300 ? ALA B 305 ? HIS B 300 ALA B 305 1 ? 6  
HELX_P HELX_P19 AC1 SER B 310 ? PHE B 315 ? SER B 310 PHE B 315 1 ? 6  
HELX_P HELX_P20 AC2 ASN B 345 ? ILE B 357 ? ASN B 345 ILE B 357 1 ? 13 
HELX_P HELX_P21 AC3 ASP B 358 ? PHE B 363 ? ASP B 358 PHE B 363 5 ? 6  
HELX_P HELX_P22 AC4 ALA B 398 ? SER B 416 ? ALA B 398 SER B 416 1 ? 19 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 56  ? THR A 57  ? LEU A 56  THR A 57  
AA1 2 ARG A 107 ? TYR A 112 ? ARG A 107 TYR A 112 
AA1 3 GLY A 85  ? ARG A 89  ? GLY A 85  ARG A 89  
AA1 4 GLY A 129 ? ILE A 130 ? GLY A 129 ILE A 130 
AA2 1 GLY A 321 ? GLU A 323 ? GLY A 321 GLU A 323 
AA2 2 TRP A 330 ? THR A 332 ? TRP A 330 THR A 332 
AA3 1 LEU B 56  ? THR B 57  ? LEU B 56  THR B 57  
AA3 2 ARG B 107 ? TYR B 112 ? ARG B 107 TYR B 112 
AA3 3 GLY B 85  ? ARG B 89  ? GLY B 85  ARG B 89  
AA3 4 GLY B 129 ? ILE B 130 ? GLY B 129 ILE B 130 
AA4 1 GLY B 321 ? GLU B 323 ? GLY B 321 GLU B 323 
AA4 2 TRP B 330 ? THR B 332 ? TRP B 330 THR B 332 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 56  ? N LEU A 56  O TRP A 108 ? O TRP A 108 
AA1 2 3 O TYR A 109 ? O TYR A 109 N ARG A 88  ? N ARG A 88  
AA1 3 4 N ARG A 89  ? N ARG A 89  O GLY A 129 ? O GLY A 129 
AA2 1 2 N GLU A 323 ? N GLU A 323 O TRP A 330 ? O TRP A 330 
AA3 1 2 N LEU B 56  ? N LEU B 56  O TRP B 108 ? O TRP B 108 
AA3 2 3 O TYR B 109 ? O TYR B 109 N ARG B 88  ? N ARG B 88  
AA3 3 4 N ARG B 89  ? N ARG B 89  O GLY B 129 ? O GLY B 129 
AA4 1 2 N GLU B 323 ? N GLU B 323 O TRP B 330 ? O TRP B 330 
# 
_pdbx_entry_details.entry_id                   8FG2 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE A ARG 10  ? ? CZ A ARG 10  ? ? NH1 A ARG 10  ? ? 117.01 120.30 -3.29 0.50 N 
2  1 NE A ARG 149 ? ? CZ A ARG 149 ? ? NH1 A ARG 149 ? ? 117.09 120.30 -3.21 0.50 N 
3  1 NE A ARG 149 ? ? CZ A ARG 149 ? ? NH2 A ARG 149 ? ? 123.45 120.30 3.15  0.50 N 
4  1 NE A ARG 203 ? ? CZ A ARG 203 ? ? NH2 A ARG 203 ? ? 123.31 120.30 3.01  0.50 N 
5  1 NE A ARG 226 ? ? CZ A ARG 226 ? ? NH2 A ARG 226 ? ? 124.46 120.30 4.16  0.50 N 
6  1 NE A ARG 259 ? ? CZ A ARG 259 ? ? NH2 A ARG 259 ? ? 124.05 120.30 3.75  0.50 N 
7  1 NE A ARG 262 ? ? CZ A ARG 262 ? ? NH2 A ARG 262 ? ? 124.34 120.30 4.04  0.50 N 
8  1 NE B ARG 10  ? ? CZ B ARG 10  ? ? NH1 B ARG 10  ? ? 116.96 120.30 -3.34 0.50 N 
9  1 NE B ARG 149 ? ? CZ B ARG 149 ? ? NH1 B ARG 149 ? ? 117.14 120.30 -3.16 0.50 N 
10 1 NE B ARG 149 ? ? CZ B ARG 149 ? ? NH2 B ARG 149 ? ? 123.41 120.30 3.11  0.50 N 
11 1 NE B ARG 226 ? ? CZ B ARG 226 ? ? NH2 B ARG 226 ? ? 124.42 120.30 4.12  0.50 N 
12 1 NE B ARG 259 ? ? CZ B ARG 259 ? ? NH2 B ARG 259 ? ? 124.04 120.30 3.74  0.50 N 
13 1 NE B ARG 262 ? ? CZ B ARG 262 ? ? NH2 B ARG 262 ? ? 124.29 120.30 3.99  0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 20  ? ? -75.60  -167.09 
2  1 THR A 49  ? ? -104.02 -134.49 
3  1 LYS A 61  ? ? -141.87 10.43   
4  1 PRO A 67  ? ? -53.13  173.35  
5  1 PRO A 117 ? ? -56.36  172.84  
6  1 PRO A 162 ? ? -88.41  49.01   
7  1 ALA A 173 ? ? -57.48  175.91  
8  1 LEU A 219 ? ? 55.02   -137.80 
9  1 ALA A 220 ? ? 40.98   -123.36 
10 1 TYR A 298 ? ? -34.11  121.49  
11 1 PRO A 326 ? ? -63.76  0.24    
12 1 PRO B 20  ? ? -75.73  -167.03 
13 1 THR B 49  ? ? -104.06 -134.40 
14 1 LYS B 61  ? ? -141.89 10.48   
15 1 PRO B 67  ? ? -53.15  173.42  
16 1 PRO B 117 ? ? -56.39  172.92  
17 1 PRO B 162 ? ? -88.40  48.97   
18 1 ALA B 173 ? ? -57.51  175.87  
19 1 LEU B 219 ? ? 55.07   -137.81 
20 1 ALA B 220 ? ? 40.91   -123.34 
21 1 TYR B 298 ? ? -33.99  121.44  
22 1 PRO B 326 ? ? -63.76  0.32    
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 88 ? ? 0.077 'SIDE CHAIN' 
2 1 ARG B 88 ? ? 0.077 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8FG2 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   100 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'RIGID BODY FIT' 
# 
_em_3d_reconstruction.entry_id                    8FG2 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  6 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               10000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          1 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '20 mM Tris (pH 7.5), 150 mM NaCl, 10 mM MgCl2, 10 mM CaCl2' 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Nucleocapsid dimer is comprised of A chain and B chain' 
_em_entity_assembly.details              
'For each monomer that comprises the dimer structure, residues 1-49 were fit into the map separately from residues 50 - 419.' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                8FG2 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           14 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        ? 
_em_image_scans.dimension_width         ? 
_em_image_scans.frames_per_image        30 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        8FG2 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           59000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             BASIC 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    'SILICON NITRIDE' 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        Homemade 
_em_sample_support.details          
'Samples were incubated with Ni-NTA coated microchips for 1 minute prior to plunge freezing into liquid ethane.' 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8FG2 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   298 
_em_vitrification.instrument            'FEI VITROBOT MARK III' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               
;A Mark III Vitrobot was used to plunge samples into liquid ethane, operating at room temperature and 100% humidity with 3 - 4 seconds blot time
;
# 
_em_experiment.entry_id                8FG2 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8FG2 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
GLN N    N N N 74  
GLN CA   C N S 75  
GLN C    C N N 76  
GLN O    O N N 77  
GLN CB   C N N 78  
GLN CG   C N N 79  
GLN CD   C N N 80  
GLN OE1  O N N 81  
GLN NE2  N N N 82  
GLN OXT  O N N 83  
GLN H    H N N 84  
GLN H2   H N N 85  
GLN HA   H N N 86  
GLN HB2  H N N 87  
GLN HB3  H N N 88  
GLN HG2  H N N 89  
GLN HG3  H N N 90  
GLN HE21 H N N 91  
GLN HE22 H N N 92  
GLN HXT  H N N 93  
GLU N    N N N 94  
GLU CA   C N S 95  
GLU C    C N N 96  
GLU O    O N N 97  
GLU CB   C N N 98  
GLU CG   C N N 99  
GLU CD   C N N 100 
GLU OE1  O N N 101 
GLU OE2  O N N 102 
GLU OXT  O N N 103 
GLU H    H N N 104 
GLU H2   H N N 105 
GLU HA   H N N 106 
GLU HB2  H N N 107 
GLU HB3  H N N 108 
GLU HG2  H N N 109 
GLU HG3  H N N 110 
GLU HE2  H N N 111 
GLU HXT  H N N 112 
GLY N    N N N 113 
GLY CA   C N N 114 
GLY C    C N N 115 
GLY O    O N N 116 
GLY OXT  O N N 117 
GLY H    H N N 118 
GLY H2   H N N 119 
GLY HA2  H N N 120 
GLY HA3  H N N 121 
GLY HXT  H N N 122 
HIS N    N N N 123 
HIS CA   C N S 124 
HIS C    C N N 125 
HIS O    O N N 126 
HIS CB   C N N 127 
HIS CG   C Y N 128 
HIS ND1  N Y N 129 
HIS CD2  C Y N 130 
HIS CE1  C Y N 131 
HIS NE2  N Y N 132 
HIS OXT  O N N 133 
HIS H    H N N 134 
HIS H2   H N N 135 
HIS HA   H N N 136 
HIS HB2  H N N 137 
HIS HB3  H N N 138 
HIS HD1  H N N 139 
HIS HD2  H N N 140 
HIS HE1  H N N 141 
HIS HE2  H N N 142 
HIS HXT  H N N 143 
ILE N    N N N 144 
ILE CA   C N S 145 
ILE C    C N N 146 
ILE O    O N N 147 
ILE CB   C N S 148 
ILE CG1  C N N 149 
ILE CG2  C N N 150 
ILE CD1  C N N 151 
ILE OXT  O N N 152 
ILE H    H N N 153 
ILE H2   H N N 154 
ILE HA   H N N 155 
ILE HB   H N N 156 
ILE HG12 H N N 157 
ILE HG13 H N N 158 
ILE HG21 H N N 159 
ILE HG22 H N N 160 
ILE HG23 H N N 161 
ILE HD11 H N N 162 
ILE HD12 H N N 163 
ILE HD13 H N N 164 
ILE HXT  H N N 165 
LEU N    N N N 166 
LEU CA   C N S 167 
LEU C    C N N 168 
LEU O    O N N 169 
LEU CB   C N N 170 
LEU CG   C N N 171 
LEU CD1  C N N 172 
LEU CD2  C N N 173 
LEU OXT  O N N 174 
LEU H    H N N 175 
LEU H2   H N N 176 
LEU HA   H N N 177 
LEU HB2  H N N 178 
LEU HB3  H N N 179 
LEU HG   H N N 180 
LEU HD11 H N N 181 
LEU HD12 H N N 182 
LEU HD13 H N N 183 
LEU HD21 H N N 184 
LEU HD22 H N N 185 
LEU HD23 H N N 186 
LEU HXT  H N N 187 
LYS N    N N N 188 
LYS CA   C N S 189 
LYS C    C N N 190 
LYS O    O N N 191 
LYS CB   C N N 192 
LYS CG   C N N 193 
LYS CD   C N N 194 
LYS CE   C N N 195 
LYS NZ   N N N 196 
LYS OXT  O N N 197 
LYS H    H N N 198 
LYS H2   H N N 199 
LYS HA   H N N 200 
LYS HB2  H N N 201 
LYS HB3  H N N 202 
LYS HG2  H N N 203 
LYS HG3  H N N 204 
LYS HD2  H N N 205 
LYS HD3  H N N 206 
LYS HE2  H N N 207 
LYS HE3  H N N 208 
LYS HZ1  H N N 209 
LYS HZ2  H N N 210 
LYS HZ3  H N N 211 
LYS HXT  H N N 212 
MET N    N N N 213 
MET CA   C N S 214 
MET C    C N N 215 
MET O    O N N 216 
MET CB   C N N 217 
MET CG   C N N 218 
MET SD   S N N 219 
MET CE   C N N 220 
MET OXT  O N N 221 
MET H    H N N 222 
MET H2   H N N 223 
MET HA   H N N 224 
MET HB2  H N N 225 
MET HB3  H N N 226 
MET HG2  H N N 227 
MET HG3  H N N 228 
MET HE1  H N N 229 
MET HE2  H N N 230 
MET HE3  H N N 231 
MET HXT  H N N 232 
PHE N    N N N 233 
PHE CA   C N S 234 
PHE C    C N N 235 
PHE O    O N N 236 
PHE CB   C N N 237 
PHE CG   C Y N 238 
PHE CD1  C Y N 239 
PHE CD2  C Y N 240 
PHE CE1  C Y N 241 
PHE CE2  C Y N 242 
PHE CZ   C Y N 243 
PHE OXT  O N N 244 
PHE H    H N N 245 
PHE H2   H N N 246 
PHE HA   H N N 247 
PHE HB2  H N N 248 
PHE HB3  H N N 249 
PHE HD1  H N N 250 
PHE HD2  H N N 251 
PHE HE1  H N N 252 
PHE HE2  H N N 253 
PHE HZ   H N N 254 
PHE HXT  H N N 255 
PRO N    N N N 256 
PRO CA   C N S 257 
PRO C    C N N 258 
PRO O    O N N 259 
PRO CB   C N N 260 
PRO CG   C N N 261 
PRO CD   C N N 262 
PRO OXT  O N N 263 
PRO H    H N N 264 
PRO HA   H N N 265 
PRO HB2  H N N 266 
PRO HB3  H N N 267 
PRO HG2  H N N 268 
PRO HG3  H N N 269 
PRO HD2  H N N 270 
PRO HD3  H N N 271 
PRO HXT  H N N 272 
SER N    N N N 273 
SER CA   C N S 274 
SER C    C N N 275 
SER O    O N N 276 
SER CB   C N N 277 
SER OG   O N N 278 
SER OXT  O N N 279 
SER H    H N N 280 
SER H2   H N N 281 
SER HA   H N N 282 
SER HB2  H N N 283 
SER HB3  H N N 284 
SER HG   H N N 285 
SER HXT  H N N 286 
THR N    N N N 287 
THR CA   C N S 288 
THR C    C N N 289 
THR O    O N N 290 
THR CB   C N R 291 
THR OG1  O N N 292 
THR CG2  C N N 293 
THR OXT  O N N 294 
THR H    H N N 295 
THR H2   H N N 296 
THR HA   H N N 297 
THR HB   H N N 298 
THR HG1  H N N 299 
THR HG21 H N N 300 
THR HG22 H N N 301 
THR HG23 H N N 302 
THR HXT  H N N 303 
TRP N    N N N 304 
TRP CA   C N S 305 
TRP C    C N N 306 
TRP O    O N N 307 
TRP CB   C N N 308 
TRP CG   C Y N 309 
TRP CD1  C Y N 310 
TRP CD2  C Y N 311 
TRP NE1  N Y N 312 
TRP CE2  C Y N 313 
TRP CE3  C Y N 314 
TRP CZ2  C Y N 315 
TRP CZ3  C Y N 316 
TRP CH2  C Y N 317 
TRP OXT  O N N 318 
TRP H    H N N 319 
TRP H2   H N N 320 
TRP HA   H N N 321 
TRP HB2  H N N 322 
TRP HB3  H N N 323 
TRP HD1  H N N 324 
TRP HE1  H N N 325 
TRP HE3  H N N 326 
TRP HZ2  H N N 327 
TRP HZ3  H N N 328 
TRP HH2  H N N 329 
TRP HXT  H N N 330 
TYR N    N N N 331 
TYR CA   C N S 332 
TYR C    C N N 333 
TYR O    O N N 334 
TYR CB   C N N 335 
TYR CG   C Y N 336 
TYR CD1  C Y N 337 
TYR CD2  C Y N 338 
TYR CE1  C Y N 339 
TYR CE2  C Y N 340 
TYR CZ   C Y N 341 
TYR OH   O N N 342 
TYR OXT  O N N 343 
TYR H    H N N 344 
TYR H2   H N N 345 
TYR HA   H N N 346 
TYR HB2  H N N 347 
TYR HB3  H N N 348 
TYR HD1  H N N 349 
TYR HD2  H N N 350 
TYR HE1  H N N 351 
TYR HE2  H N N 352 
TYR HH   H N N 353 
TYR HXT  H N N 354 
VAL N    N N N 355 
VAL CA   C N S 356 
VAL C    C N N 357 
VAL O    O N N 358 
VAL CB   C N N 359 
VAL CG1  C N N 360 
VAL CG2  C N N 361 
VAL OXT  O N N 362 
VAL H    H N N 363 
VAL H2   H N N 364 
VAL HA   H N N 365 
VAL HB   H N N 366 
VAL HG11 H N N 367 
VAL HG12 H N N 368 
VAL HG13 H N N 369 
VAL HG21 H N N 370 
VAL HG22 H N N 371 
VAL HG23 H N N 372 
VAL HXT  H N N 373 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
GLN N   CA   sing N N 70  
GLN N   H    sing N N 71  
GLN N   H2   sing N N 72  
GLN CA  C    sing N N 73  
GLN CA  CB   sing N N 74  
GLN CA  HA   sing N N 75  
GLN C   O    doub N N 76  
GLN C   OXT  sing N N 77  
GLN CB  CG   sing N N 78  
GLN CB  HB2  sing N N 79  
GLN CB  HB3  sing N N 80  
GLN CG  CD   sing N N 81  
GLN CG  HG2  sing N N 82  
GLN CG  HG3  sing N N 83  
GLN CD  OE1  doub N N 84  
GLN CD  NE2  sing N N 85  
GLN NE2 HE21 sing N N 86  
GLN NE2 HE22 sing N N 87  
GLN OXT HXT  sing N N 88  
GLU N   CA   sing N N 89  
GLU N   H    sing N N 90  
GLU N   H2   sing N N 91  
GLU CA  C    sing N N 92  
GLU CA  CB   sing N N 93  
GLU CA  HA   sing N N 94  
GLU C   O    doub N N 95  
GLU C   OXT  sing N N 96  
GLU CB  CG   sing N N 97  
GLU CB  HB2  sing N N 98  
GLU CB  HB3  sing N N 99  
GLU CG  CD   sing N N 100 
GLU CG  HG2  sing N N 101 
GLU CG  HG3  sing N N 102 
GLU CD  OE1  doub N N 103 
GLU CD  OE2  sing N N 104 
GLU OE2 HE2  sing N N 105 
GLU OXT HXT  sing N N 106 
GLY N   CA   sing N N 107 
GLY N   H    sing N N 108 
GLY N   H2   sing N N 109 
GLY CA  C    sing N N 110 
GLY CA  HA2  sing N N 111 
GLY CA  HA3  sing N N 112 
GLY C   O    doub N N 113 
GLY C   OXT  sing N N 114 
GLY OXT HXT  sing N N 115 
HIS N   CA   sing N N 116 
HIS N   H    sing N N 117 
HIS N   H2   sing N N 118 
HIS CA  C    sing N N 119 
HIS CA  CB   sing N N 120 
HIS CA  HA   sing N N 121 
HIS C   O    doub N N 122 
HIS C   OXT  sing N N 123 
HIS CB  CG   sing N N 124 
HIS CB  HB2  sing N N 125 
HIS CB  HB3  sing N N 126 
HIS CG  ND1  sing Y N 127 
HIS CG  CD2  doub Y N 128 
HIS ND1 CE1  doub Y N 129 
HIS ND1 HD1  sing N N 130 
HIS CD2 NE2  sing Y N 131 
HIS CD2 HD2  sing N N 132 
HIS CE1 NE2  sing Y N 133 
HIS CE1 HE1  sing N N 134 
HIS NE2 HE2  sing N N 135 
HIS OXT HXT  sing N N 136 
ILE N   CA   sing N N 137 
ILE N   H    sing N N 138 
ILE N   H2   sing N N 139 
ILE CA  C    sing N N 140 
ILE CA  CB   sing N N 141 
ILE CA  HA   sing N N 142 
ILE C   O    doub N N 143 
ILE C   OXT  sing N N 144 
ILE CB  CG1  sing N N 145 
ILE CB  CG2  sing N N 146 
ILE CB  HB   sing N N 147 
ILE CG1 CD1  sing N N 148 
ILE CG1 HG12 sing N N 149 
ILE CG1 HG13 sing N N 150 
ILE CG2 HG21 sing N N 151 
ILE CG2 HG22 sing N N 152 
ILE CG2 HG23 sing N N 153 
ILE CD1 HD11 sing N N 154 
ILE CD1 HD12 sing N N 155 
ILE CD1 HD13 sing N N 156 
ILE OXT HXT  sing N N 157 
LEU N   CA   sing N N 158 
LEU N   H    sing N N 159 
LEU N   H2   sing N N 160 
LEU CA  C    sing N N 161 
LEU CA  CB   sing N N 162 
LEU CA  HA   sing N N 163 
LEU C   O    doub N N 164 
LEU C   OXT  sing N N 165 
LEU CB  CG   sing N N 166 
LEU CB  HB2  sing N N 167 
LEU CB  HB3  sing N N 168 
LEU CG  CD1  sing N N 169 
LEU CG  CD2  sing N N 170 
LEU CG  HG   sing N N 171 
LEU CD1 HD11 sing N N 172 
LEU CD1 HD12 sing N N 173 
LEU CD1 HD13 sing N N 174 
LEU CD2 HD21 sing N N 175 
LEU CD2 HD22 sing N N 176 
LEU CD2 HD23 sing N N 177 
LEU OXT HXT  sing N N 178 
LYS N   CA   sing N N 179 
LYS N   H    sing N N 180 
LYS N   H2   sing N N 181 
LYS CA  C    sing N N 182 
LYS CA  CB   sing N N 183 
LYS CA  HA   sing N N 184 
LYS C   O    doub N N 185 
LYS C   OXT  sing N N 186 
LYS CB  CG   sing N N 187 
LYS CB  HB2  sing N N 188 
LYS CB  HB3  sing N N 189 
LYS CG  CD   sing N N 190 
LYS CG  HG2  sing N N 191 
LYS CG  HG3  sing N N 192 
LYS CD  CE   sing N N 193 
LYS CD  HD2  sing N N 194 
LYS CD  HD3  sing N N 195 
LYS CE  NZ   sing N N 196 
LYS CE  HE2  sing N N 197 
LYS CE  HE3  sing N N 198 
LYS NZ  HZ1  sing N N 199 
LYS NZ  HZ2  sing N N 200 
LYS NZ  HZ3  sing N N 201 
LYS OXT HXT  sing N N 202 
MET N   CA   sing N N 203 
MET N   H    sing N N 204 
MET N   H2   sing N N 205 
MET CA  C    sing N N 206 
MET CA  CB   sing N N 207 
MET CA  HA   sing N N 208 
MET C   O    doub N N 209 
MET C   OXT  sing N N 210 
MET CB  CG   sing N N 211 
MET CB  HB2  sing N N 212 
MET CB  HB3  sing N N 213 
MET CG  SD   sing N N 214 
MET CG  HG2  sing N N 215 
MET CG  HG3  sing N N 216 
MET SD  CE   sing N N 217 
MET CE  HE1  sing N N 218 
MET CE  HE2  sing N N 219 
MET CE  HE3  sing N N 220 
MET OXT HXT  sing N N 221 
PHE N   CA   sing N N 222 
PHE N   H    sing N N 223 
PHE N   H2   sing N N 224 
PHE CA  C    sing N N 225 
PHE CA  CB   sing N N 226 
PHE CA  HA   sing N N 227 
PHE C   O    doub N N 228 
PHE C   OXT  sing N N 229 
PHE CB  CG   sing N N 230 
PHE CB  HB2  sing N N 231 
PHE CB  HB3  sing N N 232 
PHE CG  CD1  doub Y N 233 
PHE CG  CD2  sing Y N 234 
PHE CD1 CE1  sing Y N 235 
PHE CD1 HD1  sing N N 236 
PHE CD2 CE2  doub Y N 237 
PHE CD2 HD2  sing N N 238 
PHE CE1 CZ   doub Y N 239 
PHE CE1 HE1  sing N N 240 
PHE CE2 CZ   sing Y N 241 
PHE CE2 HE2  sing N N 242 
PHE CZ  HZ   sing N N 243 
PHE OXT HXT  sing N N 244 
PRO N   CA   sing N N 245 
PRO N   CD   sing N N 246 
PRO N   H    sing N N 247 
PRO CA  C    sing N N 248 
PRO CA  CB   sing N N 249 
PRO CA  HA   sing N N 250 
PRO C   O    doub N N 251 
PRO C   OXT  sing N N 252 
PRO CB  CG   sing N N 253 
PRO CB  HB2  sing N N 254 
PRO CB  HB3  sing N N 255 
PRO CG  CD   sing N N 256 
PRO CG  HG2  sing N N 257 
PRO CG  HG3  sing N N 258 
PRO CD  HD2  sing N N 259 
PRO CD  HD3  sing N N 260 
PRO OXT HXT  sing N N 261 
SER N   CA   sing N N 262 
SER N   H    sing N N 263 
SER N   H2   sing N N 264 
SER CA  C    sing N N 265 
SER CA  CB   sing N N 266 
SER CA  HA   sing N N 267 
SER C   O    doub N N 268 
SER C   OXT  sing N N 269 
SER CB  OG   sing N N 270 
SER CB  HB2  sing N N 271 
SER CB  HB3  sing N N 272 
SER OG  HG   sing N N 273 
SER OXT HXT  sing N N 274 
THR N   CA   sing N N 275 
THR N   H    sing N N 276 
THR N   H2   sing N N 277 
THR CA  C    sing N N 278 
THR CA  CB   sing N N 279 
THR CA  HA   sing N N 280 
THR C   O    doub N N 281 
THR C   OXT  sing N N 282 
THR CB  OG1  sing N N 283 
THR CB  CG2  sing N N 284 
THR CB  HB   sing N N 285 
THR OG1 HG1  sing N N 286 
THR CG2 HG21 sing N N 287 
THR CG2 HG22 sing N N 288 
THR CG2 HG23 sing N N 289 
THR OXT HXT  sing N N 290 
TRP N   CA   sing N N 291 
TRP N   H    sing N N 292 
TRP N   H2   sing N N 293 
TRP CA  C    sing N N 294 
TRP CA  CB   sing N N 295 
TRP CA  HA   sing N N 296 
TRP C   O    doub N N 297 
TRP C   OXT  sing N N 298 
TRP CB  CG   sing N N 299 
TRP CB  HB2  sing N N 300 
TRP CB  HB3  sing N N 301 
TRP CG  CD1  doub Y N 302 
TRP CG  CD2  sing Y N 303 
TRP CD1 NE1  sing Y N 304 
TRP CD1 HD1  sing N N 305 
TRP CD2 CE2  doub Y N 306 
TRP CD2 CE3  sing Y N 307 
TRP NE1 CE2  sing Y N 308 
TRP NE1 HE1  sing N N 309 
TRP CE2 CZ2  sing Y N 310 
TRP CE3 CZ3  doub Y N 311 
TRP CE3 HE3  sing N N 312 
TRP CZ2 CH2  doub Y N 313 
TRP CZ2 HZ2  sing N N 314 
TRP CZ3 CH2  sing Y N 315 
TRP CZ3 HZ3  sing N N 316 
TRP CH2 HH2  sing N N 317 
TRP OXT HXT  sing N N 318 
TYR N   CA   sing N N 319 
TYR N   H    sing N N 320 
TYR N   H2   sing N N 321 
TYR CA  C    sing N N 322 
TYR CA  CB   sing N N 323 
TYR CA  HA   sing N N 324 
TYR C   O    doub N N 325 
TYR C   OXT  sing N N 326 
TYR CB  CG   sing N N 327 
TYR CB  HB2  sing N N 328 
TYR CB  HB3  sing N N 329 
TYR CG  CD1  doub Y N 330 
TYR CG  CD2  sing Y N 331 
TYR CD1 CE1  sing Y N 332 
TYR CD1 HD1  sing N N 333 
TYR CD2 CE2  doub Y N 334 
TYR CD2 HD2  sing N N 335 
TYR CE1 CZ   doub Y N 336 
TYR CE1 HE1  sing N N 337 
TYR CE2 CZ   sing Y N 338 
TYR CE2 HE2  sing N N 339 
TYR CZ  OH   sing N N 340 
TYR OH  HH   sing N N 341 
TYR OXT HXT  sing N N 342 
VAL N   CA   sing N N 343 
VAL N   H    sing N N 344 
VAL N   H2   sing N N 345 
VAL CA  C    sing N N 346 
VAL CA  CB   sing N N 347 
VAL CA  HA   sing N N 348 
VAL C   O    doub N N 349 
VAL C   OXT  sing N N 350 
VAL CB  CG1  sing N N 351 
VAL CB  CG2  sing N N 352 
VAL CB  HB   sing N N 353 
VAL CG1 HG11 sing N N 354 
VAL CG1 HG12 sing N N 355 
VAL CG1 HG13 sing N N 356 
VAL CG2 HG21 sing N N 357 
VAL CG2 HG22 sing N N 358 
VAL CG2 HG23 sing N N 359 
VAL OXT HXT  sing N N 360 
# 
_em_admin.current_status     OBS 
_em_admin.deposition_date    2022-12-12 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8FG2 
_em_admin.last_update        2025-03-05 
_em_admin.map_release_date   2023-01-11 
_em_admin.title              'SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          2697049 
_em_entity_assembly_naturalsource.organism             'Severe acute respiratory syndrome coronavirus 2' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               1 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       INTEGRATING 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    4 
_em_image_recording.num_real_images                     300 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   10000 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? cryoSPARC ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU       ? 
MASKING                         ? 3  ? ? ? ?         ? 
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ? 
'MODEL FITTING'                 ? 7  ? 1 ? PHENIX    ? 
OTHER                           ? 8  ? ? ? ?         ? 
'MODEL REFINEMENT'              ? 9  ? 1 ? ISOLDE    ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? cryoSPARC ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? RELION    ? 
CLASSIFICATION                  ? 12 1 ? ? cryoSPARC ? 
RECONSTRUCTION                  ? 13 1 ? ? cryoSPARC ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?         ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ? 
# 
_em_specimen.concentration           0.1 
_em_specimen.details                 'Sample was enriched using Ni-NTA coated silicon nitride microchips' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Cancer Institute (NIH/NCI)' 'United States' R01CA193578 1 
'National Institutes of Health/National Cancer Institute (NIH/NCI)' 'United States' R01CA227261 2 
'National Institutes of Health/National Cancer Institute (NIH/NCI)' 'United States' R01CA219700 3 
# 
_atom_sites.entry_id                    8FG2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    C CA  . MET A 1 1   ? 84.586  91.055 97.483  1.00 0.55 ? 1   MET A CA  1 
ATOM 2    C C   . MET A 1 1   ? 85.344  90.167 96.523  1.00 0.55 ? 1   MET A C   1 
ATOM 3    O O   . MET A 1 1   ? 85.690  90.622 95.438  1.00 0.55 ? 1   MET A O   1 
ATOM 4    C CB  . MET A 1 1   ? 83.077  90.700 97.386  1.00 0.55 ? 1   MET A CB  1 
ATOM 5    C CG  . MET A 1 1   ? 82.202  91.255 98.524  1.00 0.55 ? 1   MET A CG  1 
ATOM 6    S SD  . MET A 1 1   ? 80.423  90.923 98.291  1.00 0.55 ? 1   MET A SD  1 
ATOM 7    C CE  . MET A 1 1   ? 80.420  89.121 98.532  1.00 0.55 ? 1   MET A CE  1 
ATOM 8    N N   . SER A 1 2   ? 85.604  88.899 96.883  1.00 0.67 ? 2   SER A N   1 
ATOM 9    C CA  . SER A 1 2   ? 86.224  87.938 95.997  1.00 0.67 ? 2   SER A CA  1 
ATOM 10   C C   . SER A 1 2   ? 85.672  86.585 96.409  1.00 0.67 ? 2   SER A C   1 
ATOM 11   O O   . SER A 1 2   ? 85.222  86.432 97.543  1.00 0.67 ? 2   SER A O   1 
ATOM 12   C CB  . SER A 1 2   ? 87.784  87.980 96.064  1.00 0.67 ? 2   SER A CB  1 
ATOM 13   O OG  . SER A 1 2   ? 88.274  87.953 97.406  1.00 0.67 ? 2   SER A OG  1 
ATOM 14   N N   . ASP A 1 3   ? 85.634  85.595 95.480  1.00 0.65 ? 3   ASP A N   1 
ATOM 15   C CA  . ASP A 1 3   ? 85.108  84.249 95.700  1.00 0.65 ? 3   ASP A CA  1 
ATOM 16   C C   . ASP A 1 3   ? 86.120  83.386 96.467  1.00 0.65 ? 3   ASP A C   1 
ATOM 17   O O   . ASP A 1 3   ? 85.810  82.312 96.966  1.00 0.65 ? 3   ASP A O   1 
ATOM 18   C CB  . ASP A 1 3   ? 84.743  83.623 94.311  1.00 0.65 ? 3   ASP A CB  1 
ATOM 19   C CG  . ASP A 1 3   ? 83.700  82.513 94.345  1.00 0.65 ? 3   ASP A CG  1 
ATOM 20   O OD1 . ASP A 1 3   ? 82.719  82.602 95.124  1.00 0.65 ? 3   ASP A OD1 1 
ATOM 21   O OD2 . ASP A 1 3   ? 83.792  81.590 93.492  1.00 0.65 ? 3   ASP A OD2 1 
ATOM 22   N N   . ASN A 1 4   ? 87.386  83.833 96.607  1.00 0.65 ? 4   ASN A N   1 
ATOM 23   C CA  . ASN A 1 4   ? 88.358  83.110 97.398  1.00 0.65 ? 4   ASN A CA  1 
ATOM 24   C C   . ASN A 1 4   ? 89.422  84.070 97.927  1.00 0.65 ? 4   ASN A C   1 
ATOM 25   O O   . ASN A 1 4   ? 89.569  85.186 97.420  1.00 0.65 ? 4   ASN A O   1 
ATOM 26   C CB  . ASN A 1 4   ? 88.957  81.898 96.623  1.00 0.65 ? 4   ASN A CB  1 
ATOM 27   C CG  . ASN A 1 4   ? 89.813  82.376 95.458  1.00 0.65 ? 4   ASN A CG  1 
ATOM 28   O OD1 . ASN A 1 4   ? 90.983  82.698 95.645  1.00 0.65 ? 4   ASN A OD1 1 
ATOM 29   N ND2 . ASN A 1 4   ? 89.240  82.487 94.241  1.00 0.65 ? 4   ASN A ND2 1 
ATOM 30   N N   . GLY A 1 5   ? 90.165  83.667 98.983  1.00 0.68 ? 5   GLY A N   1 
ATOM 31   C CA  . GLY A 1 5   ? 91.145  84.533 99.614  1.00 0.68 ? 5   GLY A CA  1 
ATOM 32   C C   . GLY A 1 5   ? 91.596  83.944 100.932 1.00 0.68 ? 5   GLY A C   1 
ATOM 33   O O   . GLY A 1 5   ? 91.384  82.749 101.155 1.00 0.68 ? 5   GLY A O   1 
ATOM 34   N N   . PRO A 1 6   ? 92.254  84.704 101.810 1.00 0.64 ? 6   PRO A N   1 
ATOM 35   C CA  . PRO A 1 6   ? 92.476  84.354 103.216 1.00 0.64 ? 6   PRO A CA  1 
ATOM 36   C C   . PRO A 1 6   ? 91.230  84.041 104.041 1.00 0.64 ? 6   PRO A C   1 
ATOM 37   O O   . PRO A 1 6   ? 90.118  84.321 103.608 1.00 0.64 ? 6   PRO A O   1 
ATOM 38   C CB  . PRO A 1 6   ? 93.226  85.568 103.798 1.00 0.64 ? 6   PRO A CB  1 
ATOM 39   C CG  . PRO A 1 6   ? 93.823  86.283 102.585 1.00 0.64 ? 6   PRO A CG  1 
ATOM 40   C CD  . PRO A 1 6   ? 92.774  86.037 101.504 1.00 0.64 ? 6   PRO A CD  1 
ATOM 41   N N   . GLN A 1 7   ? 91.420  83.426 105.233 1.00 0.62 ? 7   GLN A N   1 
ATOM 42   C CA  . GLN A 1 7   ? 90.387  83.149 106.234 1.00 0.62 ? 7   GLN A CA  1 
ATOM 43   C C   . GLN A 1 7   ? 89.311  82.154 105.802 1.00 0.62 ? 7   GLN A C   1 
ATOM 44   O O   . GLN A 1 7   ? 88.246  82.037 106.405 1.00 0.62 ? 7   GLN A O   1 
ATOM 45   C CB  . GLN A 1 7   ? 89.736  84.432 106.815 1.00 0.62 ? 7   GLN A CB  1 
ATOM 46   C CG  . GLN A 1 7   ? 90.707  85.520 107.336 1.00 0.62 ? 7   GLN A CG  1 
ATOM 47   C CD  . GLN A 1 7   ? 91.456  85.173 108.619 1.00 0.62 ? 7   GLN A CD  1 
ATOM 48   O OE1 . GLN A 1 7   ? 91.559  84.039 109.095 1.00 0.62 ? 7   GLN A OE1 1 
ATOM 49   N NE2 . GLN A 1 7   ? 92.050  86.238 109.211 1.00 0.62 ? 7   GLN A NE2 1 
ATOM 50   N N   . ASN A 1 8   ? 89.576  81.356 104.753 1.00 0.65 ? 8   ASN A N   1 
ATOM 51   C CA  . ASN A 1 8   ? 88.659  80.349 104.266 1.00 0.65 ? 8   ASN A CA  1 
ATOM 52   C C   . ASN A 1 8   ? 88.405  79.194 105.241 1.00 0.65 ? 8   ASN A C   1 
ATOM 53   O O   . ASN A 1 8   ? 89.288  78.662 105.910 1.00 0.65 ? 8   ASN A O   1 
ATOM 54   C CB  . ASN A 1 8   ? 89.012  79.895 102.825 1.00 0.65 ? 8   ASN A CB  1 
ATOM 55   C CG  . ASN A 1 8   ? 90.355  79.194 102.782 1.00 0.65 ? 8   ASN A CG  1 
ATOM 56   O OD1 . ASN A 1 8   ? 91.334  79.647 103.367 1.00 0.65 ? 8   ASN A OD1 1 
ATOM 57   N ND2 . ASN A 1 8   ? 90.438  78.051 102.066 1.00 0.65 ? 8   ASN A ND2 1 
ATOM 58   N N   . GLN A 1 9   ? 87.134  78.783 105.350 1.00 0.64 ? 9   GLN A N   1 
ATOM 59   C CA  . GLN A 1 9   ? 86.639  77.987 106.456 1.00 0.64 ? 9   GLN A CA  1 
ATOM 60   C C   . GLN A 1 9   ? 87.160  76.554 106.587 1.00 0.64 ? 9   GLN A C   1 
ATOM 61   O O   . GLN A 1 9   ? 87.342  76.048 107.701 1.00 0.64 ? 9   GLN A O   1 
ATOM 62   C CB  . GLN A 1 9   ? 85.089  78.008 106.416 1.00 0.64 ? 9   GLN A CB  1 
ATOM 63   C CG  . GLN A 1 9   ? 84.369  77.351 107.620 1.00 0.64 ? 9   GLN A CG  1 
ATOM 64   C CD  . GLN A 1 9   ? 82.858  77.224 107.389 1.00 0.64 ? 9   GLN A CD  1 
ATOM 65   O OE1 . GLN A 1 9   ? 82.390  76.715 106.363 1.00 0.64 ? 9   GLN A OE1 1 
ATOM 66   N NE2 . GLN A 1 9   ? 82.053  77.620 108.400 1.00 0.64 ? 9   GLN A NE2 1 
ATOM 67   N N   . ARG A 1 10  ? 87.362  75.840 105.459 1.00 0.60 ? 10  ARG A N   1 
ATOM 68   C CA  . ARG A 1 10  ? 87.492  74.388 105.453 1.00 0.60 ? 10  ARG A CA  1 
ATOM 69   C C   . ARG A 1 10  ? 88.837  73.859 104.957 1.00 0.60 ? 10  ARG A C   1 
ATOM 70   O O   . ARG A 1 10  ? 89.029  72.653 104.853 1.00 0.60 ? 10  ARG A O   1 
ATOM 71   C CB  . ARG A 1 10  ? 86.316  73.775 104.648 1.00 0.60 ? 10  ARG A CB  1 
ATOM 72   C CG  . ARG A 1 10  ? 84.940  74.204 105.215 1.00 0.60 ? 10  ARG A CG  1 
ATOM 73   C CD  . ARG A 1 10  ? 83.727  73.518 104.579 1.00 0.60 ? 10  ARG A CD  1 
ATOM 74   N NE  . ARG A 1 10  ? 82.543  74.277 105.083 1.00 0.60 ? 10  ARG A NE  1 
ATOM 75   C CZ  . ARG A 1 10  ? 81.287  73.834 105.191 1.00 0.60 ? 10  ARG A CZ  1 
ATOM 76   N NH1 . ARG A 1 10  ? 80.379  74.695 105.648 1.00 0.60 ? 10  ARG A NH1 1 
ATOM 77   N NH2 . ARG A 1 10  ? 80.927  72.592 104.897 1.00 0.60 ? 10  ARG A NH2 1 
ATOM 78   N N   . ASN A 1 11  ? 89.829  74.737 104.690 1.00 0.60 ? 11  ASN A N   1 
ATOM 79   C CA  . ASN A 1 11  ? 91.210  74.314 104.507 1.00 0.60 ? 11  ASN A CA  1 
ATOM 80   C C   . ASN A 1 11  ? 91.924  74.212 105.865 1.00 0.60 ? 11  ASN A C   1 
ATOM 81   O O   . ASN A 1 11  ? 92.855  73.429 106.051 1.00 0.60 ? 11  ASN A O   1 
ATOM 82   C CB  . ASN A 1 11  ? 91.907  75.308 103.546 1.00 0.60 ? 11  ASN A CB  1 
ATOM 83   C CG  . ASN A 1 11  ? 93.350  74.905 103.279 1.00 0.60 ? 11  ASN A CG  1 
ATOM 84   O OD1 . ASN A 1 11  ? 94.273  75.480 103.857 1.00 0.60 ? 11  ASN A OD1 1 
ATOM 85   N ND2 . ASN A 1 11  ? 93.560  73.899 102.408 1.00 0.60 ? 11  ASN A ND2 1 
ATOM 86   N N   . ALA A 1 12  ? 91.451  74.988 106.860 1.00 0.63 ? 12  ALA A N   1 
ATOM 87   C CA  . ALA A 1 12  ? 91.793  74.862 108.260 1.00 0.63 ? 12  ALA A CA  1 
ATOM 88   C C   . ALA A 1 12  ? 91.405  73.496 108.846 1.00 0.63 ? 12  ALA A C   1 
ATOM 89   O O   . ALA A 1 12  ? 90.520  72.842 108.290 1.00 0.63 ? 12  ALA A O   1 
ATOM 90   C CB  . ALA A 1 12  ? 91.101  76.002 109.039 1.00 0.63 ? 12  ALA A CB  1 
ATOM 91   N N   . PRO A 1 13  ? 92.000  72.989 109.931 1.00 0.55 ? 13  PRO A N   1 
ATOM 92   C CA  . PRO A 1 13  ? 91.670  71.671 110.468 1.00 0.55 ? 13  PRO A CA  1 
ATOM 93   C C   . PRO A 1 13  ? 90.303  71.641 111.144 1.00 0.55 ? 13  PRO A C   1 
ATOM 94   O O   . PRO A 1 13  ? 90.202  71.646 112.366 1.00 0.55 ? 13  PRO A O   1 
ATOM 95   C CB  . PRO A 1 13  ? 92.815  71.382 111.458 1.00 0.55 ? 13  PRO A CB  1 
ATOM 96   C CG  . PRO A 1 13  ? 93.285  72.768 111.906 1.00 0.55 ? 13  PRO A CG  1 
ATOM 97   C CD  . PRO A 1 13  ? 93.108  73.616 110.648 1.00 0.55 ? 13  PRO A CD  1 
ATOM 98   N N   . ARG A 1 14  ? 89.233  71.560 110.337 1.00 0.52 ? 14  ARG A N   1 
ATOM 99   C CA  . ARG A 1 14  ? 87.846  71.591 110.751 1.00 0.52 ? 14  ARG A CA  1 
ATOM 100  C C   . ARG A 1 14  ? 87.334  70.227 111.209 1.00 0.52 ? 14  ARG A C   1 
ATOM 101  O O   . ARG A 1 14  ? 86.240  70.102 111.752 1.00 0.52 ? 14  ARG A O   1 
ATOM 102  C CB  . ARG A 1 14  ? 87.024  72.080 109.522 1.00 0.52 ? 14  ARG A CB  1 
ATOM 103  C CG  . ARG A 1 14  ? 85.580  72.566 109.791 1.00 0.52 ? 14  ARG A CG  1 
ATOM 104  C CD  . ARG A 1 14  ? 85.429  73.729 110.781 1.00 0.52 ? 14  ARG A CD  1 
ATOM 105  N NE  . ARG A 1 14  ? 86.197  74.904 110.241 1.00 0.52 ? 14  ARG A NE  1 
ATOM 106  C CZ  . ARG A 1 14  ? 86.552  75.975 110.965 1.00 0.52 ? 14  ARG A CZ  1 
ATOM 107  N NH1 . ARG A 1 14  ? 87.314  76.905 110.395 1.00 0.52 ? 14  ARG A NH1 1 
ATOM 108  N NH2 . ARG A 1 14  ? 86.157  76.123 112.222 1.00 0.52 ? 14  ARG A NH2 1 
ATOM 109  N N   . ILE A 1 15  ? 88.135  69.169 110.978 1.00 0.50 ? 15  ILE A N   1 
ATOM 110  C CA  . ILE A 1 15  ? 87.758  67.782 111.187 1.00 0.50 ? 15  ILE A CA  1 
ATOM 111  C C   . ILE A 1 15  ? 88.350  67.175 112.465 1.00 0.50 ? 15  ILE A C   1 
ATOM 112  O O   . ILE A 1 15  ? 88.089  66.022 112.818 1.00 0.50 ? 15  ILE A O   1 
ATOM 113  C CB  . ILE A 1 15  ? 88.172  66.991 109.942 1.00 0.50 ? 15  ILE A CB  1 
ATOM 114  C CG1 . ILE A 1 15  ? 87.457  65.625 109.824 1.00 0.50 ? 15  ILE A CG1 1 
ATOM 115  C CG2 . ILE A 1 15  ? 89.713  66.872 109.829 1.00 0.50 ? 15  ILE A CG2 1 
ATOM 116  C CD1 . ILE A 1 15  ? 87.454  65.094 108.385 1.00 0.50 ? 15  ILE A CD1 1 
ATOM 117  N N   . THR A 1 16  ? 89.176  67.932 113.220 1.00 0.45 ? 16  THR A N   1 
ATOM 118  C CA  . THR A 1 16  ? 89.753  67.471 114.483 1.00 0.45 ? 16  THR A CA  1 
ATOM 119  C C   . THR A 1 16  ? 88.796  67.561 115.657 1.00 0.45 ? 16  THR A C   1 
ATOM 120  O O   . THR A 1 16  ? 88.687  66.619 116.438 1.00 0.45 ? 16  THR A O   1 
ATOM 121  C CB  . THR A 1 16  ? 91.035  68.199 114.870 1.00 0.45 ? 16  THR A CB  1 
ATOM 122  O OG1 . THR A 1 16  ? 90.833  69.603 114.885 1.00 0.45 ? 16  THR A OG1 1 
ATOM 123  C CG2 . THR A 1 16  ? 92.134  67.909 113.835 1.00 0.45 ? 16  THR A CG2 1 
ATOM 124  N N   . PHE A 1 17  ? 88.074  68.684 115.813 1.00 0.36 ? 17  PHE A N   1 
ATOM 125  C CA  . PHE A 1 17  ? 87.127  68.894 116.888 1.00 0.36 ? 17  PHE A CA  1 
ATOM 126  C C   . PHE A 1 17  ? 86.112  69.919 116.394 1.00 0.36 ? 17  PHE A C   1 
ATOM 127  O O   . PHE A 1 17  ? 86.399  70.704 115.492 1.00 0.36 ? 17  PHE A O   1 
ATOM 128  C CB  . PHE A 1 17  ? 87.866  69.354 118.184 1.00 0.36 ? 17  PHE A CB  1 
ATOM 129  C CG  . PHE A 1 17  ? 86.972  69.596 119.377 1.00 0.36 ? 17  PHE A CG  1 
ATOM 130  C CD1 . PHE A 1 17  ? 86.119  68.593 119.865 1.00 0.36 ? 17  PHE A CD1 1 
ATOM 131  C CD2 . PHE A 1 17  ? 86.975  70.847 120.017 1.00 0.36 ? 17  PHE A CD2 1 
ATOM 132  C CE1 . PHE A 1 17  ? 85.285  68.835 120.965 1.00 0.36 ? 17  PHE A CE1 1 
ATOM 133  C CE2 . PHE A 1 17  ? 86.154  71.088 121.124 1.00 0.36 ? 17  PHE A CE2 1 
ATOM 134  C CZ  . PHE A 1 17  ? 85.311  70.080 121.602 1.00 0.36 ? 17  PHE A CZ  1 
ATOM 135  N N   . GLY A 1 18  ? 84.879  69.912 116.954 1.00 0.45 ? 18  GLY A N   1 
ATOM 136  C CA  . GLY A 1 18  ? 83.715  70.567 116.353 1.00 0.45 ? 18  GLY A CA  1 
ATOM 137  C C   . GLY A 1 18  ? 83.323  69.937 115.039 1.00 0.45 ? 18  GLY A C   1 
ATOM 138  O O   . GLY A 1 18  ? 83.407  68.722 114.887 1.00 0.45 ? 18  GLY A O   1 
ATOM 139  N N   . GLY A 1 19  ? 82.867  70.731 114.050 1.00 0.53 ? 19  GLY A N   1 
ATOM 140  C CA  . GLY A 1 19  ? 82.658  70.166 112.728 1.00 0.53 ? 19  GLY A CA  1 
ATOM 141  C C   . GLY A 1 19  ? 82.213  71.197 111.719 1.00 0.53 ? 19  GLY A C   1 
ATOM 142  O O   . GLY A 1 19  ? 81.940  72.344 112.079 1.00 0.53 ? 19  GLY A O   1 
ATOM 143  N N   . PRO A 1 20  ? 82.167  70.845 110.436 1.00 0.58 ? 20  PRO A N   1 
ATOM 144  C CA  . PRO A 1 20  ? 81.486  71.617 109.403 1.00 0.58 ? 20  PRO A CA  1 
ATOM 145  C C   . PRO A 1 20  ? 79.974  71.460 109.466 1.00 0.58 ? 20  PRO A C   1 
ATOM 146  O O   . PRO A 1 20  ? 79.446  70.939 110.441 1.00 0.58 ? 20  PRO A O   1 
ATOM 147  C CB  . PRO A 1 20  ? 82.071  71.015 108.110 1.00 0.58 ? 20  PRO A CB  1 
ATOM 148  C CG  . PRO A 1 20  ? 82.311  69.543 108.446 1.00 0.58 ? 20  PRO A CG  1 
ATOM 149  C CD  . PRO A 1 20  ? 82.686  69.573 109.926 1.00 0.58 ? 20  PRO A CD  1 
ATOM 150  N N   . SER A 1 21  ? 79.258  71.908 108.404 1.00 0.57 ? 21  SER A N   1 
ATOM 151  C CA  . SER A 1 21  ? 77.800  71.892 108.296 1.00 0.57 ? 21  SER A CA  1 
ATOM 152  C C   . SER A 1 21  ? 77.145  70.525 108.463 1.00 0.57 ? 21  SER A C   1 
ATOM 153  O O   . SER A 1 21  ? 76.059  70.435 109.028 1.00 0.57 ? 21  SER A O   1 
ATOM 154  C CB  . SER A 1 21  ? 77.288  72.470 106.939 1.00 0.57 ? 21  SER A CB  1 
ATOM 155  O OG  . SER A 1 21  ? 77.913  73.708 106.563 1.00 0.57 ? 21  SER A OG  1 
ATOM 156  N N   . ASP A 1 22  ? 77.810  69.448 107.996 1.00 0.54 ? 22  ASP A N   1 
ATOM 157  C CA  . ASP A 1 22  ? 77.320  68.085 108.032 1.00 0.54 ? 22  ASP A CA  1 
ATOM 158  C C   . ASP A 1 22  ? 78.135  67.321 109.072 1.00 0.54 ? 22  ASP A C   1 
ATOM 159  O O   . ASP A 1 22  ? 79.331  67.552 109.242 1.00 0.54 ? 22  ASP A O   1 
ATOM 160  C CB  . ASP A 1 22  ? 77.468  67.400 106.646 1.00 0.54 ? 22  ASP A CB  1 
ATOM 161  C CG  . ASP A 1 22  ? 76.592  68.080 105.598 1.00 0.54 ? 22  ASP A CG  1 
ATOM 162  O OD1 . ASP A 1 22  ? 75.683  68.860 105.976 1.00 0.54 ? 22  ASP A OD1 1 
ATOM 163  O OD2 . ASP A 1 22  ? 76.866  67.859 104.391 1.00 0.54 ? 22  ASP A OD2 1 
ATOM 164  N N   . SER A 1 23  ? 77.483  66.394 109.812 1.00 0.51 ? 23  SER A N   1 
ATOM 165  C CA  . SER A 1 23  ? 78.062  65.677 110.953 1.00 0.51 ? 23  SER A CA  1 
ATOM 166  C C   . SER A 1 23  ? 79.042  64.569 110.566 1.00 0.51 ? 23  SER A C   1 
ATOM 167  O O   . SER A 1 23  ? 79.848  64.107 111.372 1.00 0.51 ? 23  SER A O   1 
ATOM 168  C CB  . SER A 1 23  ? 76.934  65.091 111.856 1.00 0.51 ? 23  SER A CB  1 
ATOM 169  O OG  . SER A 1 23  ? 77.399  64.680 113.145 1.00 0.51 ? 23  SER A OG  1 
ATOM 170  N N   . THR A 1 24  ? 79.026  64.108 109.300 1.00 0.54 ? 24  THR A N   1 
ATOM 171  C CA  . THR A 1 24  ? 79.935  63.074 108.807 1.00 0.54 ? 24  THR A CA  1 
ATOM 172  C C   . THR A 1 24  ? 81.385  63.531 108.760 1.00 0.54 ? 24  THR A C   1 
ATOM 173  O O   . THR A 1 24  ? 81.729  64.542 108.151 1.00 0.54 ? 24  THR A O   1 
ATOM 174  C CB  . THR A 1 24  ? 79.529  62.536 107.445 1.00 0.54 ? 24  THR A CB  1 
ATOM 175  O OG1 . THR A 1 24  ? 78.165  62.150 107.481 1.00 0.54 ? 24  THR A OG1 1 
ATOM 176  C CG2 . THR A 1 24  ? 80.319  61.273 107.067 1.00 0.54 ? 24  THR A CG2 1 
ATOM 177  N N   . GLY A 1 25  ? 82.303  62.797 109.428 1.00 0.55 ? 25  GLY A N   1 
ATOM 178  C CA  . GLY A 1 25  ? 83.692  63.214 109.487 1.00 0.55 ? 25  GLY A CA  1 
ATOM 179  C C   . GLY A 1 25  ? 84.527  62.210 110.226 1.00 0.55 ? 25  GLY A C   1 
ATOM 180  O O   . GLY A 1 25  ? 84.013  61.281 110.842 1.00 0.55 ? 25  GLY A O   1 
ATOM 181  N N   . SER A 1 26  ? 85.862  62.374 110.183 1.00 0.50 ? 26  SER A N   1 
ATOM 182  C CA  . SER A 1 26  ? 86.822  61.386 110.670 1.00 0.50 ? 26  SER A CA  1 
ATOM 183  C C   . SER A 1 26  ? 87.024  61.325 112.168 1.00 0.50 ? 26  SER A C   1 
ATOM 184  O O   . SER A 1 26  ? 87.642  60.389 112.664 1.00 0.50 ? 26  SER A O   1 
ATOM 185  C CB  . SER A 1 26  ? 88.236  61.603 110.073 1.00 0.50 ? 26  SER A CB  1 
ATOM 186  O OG  . SER A 1 26  ? 88.161  61.733 108.654 1.00 0.50 ? 26  SER A OG  1 
ATOM 187  N N   . ASN A 1 27  ? 86.544  62.338 112.929 1.00 0.45 ? 27  ASN A N   1 
ATOM 188  C CA  . ASN A 1 27  ? 86.783  62.484 114.361 1.00 0.45 ? 27  ASN A CA  1 
ATOM 189  C C   . ASN A 1 27  ? 88.284  62.518 114.688 1.00 0.45 ? 27  ASN A C   1 
ATOM 190  O O   . ASN A 1 27  ? 88.802  61.739 115.485 1.00 0.45 ? 27  ASN A O   1 
ATOM 191  C CB  . ASN A 1 27  ? 85.974  61.424 115.165 1.00 0.45 ? 27  ASN A CB  1 
ATOM 192  C CG  . ASN A 1 27  ? 85.969  61.691 116.667 1.00 0.45 ? 27  ASN A CG  1 
ATOM 193  O OD1 . ASN A 1 27  ? 85.933  62.836 117.122 1.00 0.45 ? 27  ASN A OD1 1 
ATOM 194  N ND2 . ASN A 1 27  ? 85.995  60.605 117.474 1.00 0.45 ? 27  ASN A ND2 1 
ATOM 195  N N   . GLN A 1 28  ? 89.035  63.442 114.044 1.00 0.45 ? 28  GLN A N   1 
ATOM 196  C CA  . GLN A 1 28  ? 90.453  63.240 113.769 1.00 0.45 ? 28  GLN A CA  1 
ATOM 197  C C   . GLN A 1 28  ? 91.369  63.556 114.953 1.00 0.45 ? 28  GLN A C   1 
ATOM 198  O O   . GLN A 1 28  ? 92.589  63.431 114.898 1.00 0.45 ? 28  GLN A O   1 
ATOM 199  C CB  . GLN A 1 28  ? 90.834  64.104 112.531 1.00 0.45 ? 28  GLN A CB  1 
ATOM 200  C CG  . GLN A 1 28  ? 92.242  63.897 111.915 1.00 0.45 ? 28  GLN A CG  1 
ATOM 201  C CD  . GLN A 1 28  ? 92.441  62.480 111.379 1.00 0.45 ? 28  GLN A CD  1 
ATOM 202  O OE1 . GLN A 1 28  ? 91.493  61.764 111.054 1.00 0.45 ? 28  GLN A OE1 1 
ATOM 203  N NE2 . GLN A 1 28  ? 93.725  62.077 111.239 1.00 0.45 ? 28  GLN A NE2 1 
ATOM 204  N N   . ASN A 1 29  ? 90.778  63.937 116.101 1.00 0.43 ? 29  ASN A N   1 
ATOM 205  C CA  . ASN A 1 29  ? 91.451  64.022 117.384 1.00 0.43 ? 29  ASN A CA  1 
ATOM 206  C C   . ASN A 1 29  ? 92.025  62.693 117.887 1.00 0.43 ? 29  ASN A C   1 
ATOM 207  O O   . ASN A 1 29  ? 93.067  62.696 118.544 1.00 0.43 ? 29  ASN A O   1 
ATOM 208  C CB  . ASN A 1 29  ? 90.559  64.708 118.463 1.00 0.43 ? 29  ASN A CB  1 
ATOM 209  C CG  . ASN A 1 29  ? 89.238  63.980 118.715 1.00 0.43 ? 29  ASN A CG  1 
ATOM 210  O OD1 . ASN A 1 29  ? 89.170  63.088 119.556 1.00 0.43 ? 29  ASN A OD1 1 
ATOM 211  N ND2 . ASN A 1 29  ? 88.158  64.397 118.023 1.00 0.43 ? 29  ASN A ND2 1 
ATOM 212  N N   . GLY A 1 30  ? 91.364  61.547 117.589 1.00 0.49 ? 30  GLY A N   1 
ATOM 213  C CA  . GLY A 1 30  ? 91.786  60.209 118.016 1.00 0.49 ? 30  GLY A CA  1 
ATOM 214  C C   . GLY A 1 30  ? 91.866  60.032 119.510 1.00 0.49 ? 30  GLY A C   1 
ATOM 215  O O   . GLY A 1 30  ? 90.868  60.107 120.218 1.00 0.49 ? 30  GLY A O   1 
ATOM 216  N N   . GLU A 1 31  ? 93.077  59.806 120.037 1.00 0.42 ? 31  GLU A N   1 
ATOM 217  C CA  . GLU A 1 31  ? 93.344  59.725 121.456 1.00 0.42 ? 31  GLU A CA  1 
ATOM 218  C C   . GLU A 1 31  ? 93.331  61.084 122.151 1.00 0.42 ? 31  GLU A C   1 
ATOM 219  O O   . GLU A 1 31  ? 93.295  61.171 123.374 1.00 0.42 ? 31  GLU A O   1 
ATOM 220  C CB  . GLU A 1 31  ? 94.733  59.073 121.699 1.00 0.42 ? 31  GLU A CB  1 
ATOM 221  C CG  . GLU A 1 31  ? 94.854  57.613 121.186 1.00 0.42 ? 31  GLU A CG  1 
ATOM 222  C CD  . GLU A 1 31  ? 95.093  57.481 119.678 1.00 0.42 ? 31  GLU A CD  1 
ATOM 223  O OE1 . GLU A 1 31  ? 95.211  58.528 118.985 1.00 0.42 ? 31  GLU A OE1 1 
ATOM 224  O OE2 . GLU A 1 31  ? 95.150  56.317 119.214 1.00 0.42 ? 31  GLU A OE2 1 
ATOM 225  N N   . ARG A 1 32  ? 93.389  62.187 121.372 1.00 0.37 ? 32  ARG A N   1 
ATOM 226  C CA  . ARG A 1 32  ? 93.393  63.565 121.837 1.00 0.37 ? 32  ARG A CA  1 
ATOM 227  C C   . ARG A 1 32  ? 94.567  63.922 122.745 1.00 0.37 ? 32  ARG A C   1 
ATOM 228  O O   . ARG A 1 32  ? 94.467  64.710 123.682 1.00 0.37 ? 32  ARG A O   1 
ATOM 229  C CB  . ARG A 1 32  ? 92.016  63.987 122.412 1.00 0.37 ? 32  ARG A CB  1 
ATOM 230  C CG  . ARG A 1 32  ? 91.737  65.508 122.389 1.00 0.37 ? 32  ARG A CG  1 
ATOM 231  C CD  . ARG A 1 32  ? 90.294  65.836 122.781 1.00 0.37 ? 32  ARG A CD  1 
ATOM 232  N NE  . ARG A 1 32  ? 90.114  67.321 122.614 1.00 0.37 ? 32  ARG A NE  1 
ATOM 233  C CZ  . ARG A 1 32  ? 88.937  67.917 122.382 1.00 0.37 ? 32  ARG A CZ  1 
ATOM 234  N NH1 . ARG A 1 32  ? 88.874  69.237 122.219 1.00 0.37 ? 32  ARG A NH1 1 
ATOM 235  N NH2 . ARG A 1 32  ? 87.812  67.215 122.302 1.00 0.37 ? 32  ARG A NH2 1 
ATOM 236  N N   . SER A 1 33  ? 95.752  63.375 122.410 1.00 0.36 ? 33  SER A N   1 
ATOM 237  C CA  . SER A 1 33  ? 97.029  63.610 123.084 1.00 0.36 ? 33  SER A CA  1 
ATOM 238  C C   . SER A 1 33  ? 97.504  65.053 122.975 1.00 0.36 ? 33  SER A C   1 
ATOM 239  O O   . SER A 1 33  ? 98.059  65.627 123.905 1.00 0.36 ? 33  SER A O   1 
ATOM 240  C CB  . SER A 1 33  ? 98.104  62.616 122.554 1.00 0.36 ? 33  SER A CB  1 
ATOM 241  O OG  . SER A 1 33  ? 99.365  62.746 123.214 1.00 0.36 ? 33  SER A OG  1 
ATOM 242  N N   . GLY A 1 34  ? 97.270  65.701 121.811 1.00 0.37 ? 34  GLY A N   1 
ATOM 243  C CA  . GLY A 1 34  ? 97.582  67.123 121.658 1.00 0.37 ? 34  GLY A CA  1 
ATOM 244  C C   . GLY A 1 34  ? 99.022  67.452 121.388 1.00 0.37 ? 34  GLY A C   1 
ATOM 245  O O   . GLY A 1 34  ? 99.442  68.590 121.543 1.00 0.37 ? 34  GLY A O   1 
ATOM 246  N N   . ALA A 1 35  ? 99.812  66.458 120.952 1.00 0.29 ? 35  ALA A N   1 
ATOM 247  C CA  . ALA A 1 35  ? 101.252 66.557 120.832 1.00 0.29 ? 35  ALA A CA  1 
ATOM 248  C C   . ALA A 1 35  ? 101.779 67.394 119.665 1.00 0.29 ? 35  ALA A C   1 
ATOM 249  O O   . ALA A 1 35  ? 102.958 67.729 119.603 1.00 0.29 ? 35  ALA A O   1 
ATOM 250  C CB  . ALA A 1 35  ? 101.795 65.120 120.701 1.00 0.29 ? 35  ALA A CB  1 
ATOM 251  N N   . ARG A 1 36  ? 100.923 67.717 118.674 1.00 0.23 ? 36  ARG A N   1 
ATOM 252  C CA  . ARG A 1 36  ? 101.295 68.515 117.520 1.00 0.23 ? 36  ARG A CA  1 
ATOM 253  C C   . ARG A 1 36  ? 101.679 69.963 117.803 1.00 0.23 ? 36  ARG A C   1 
ATOM 254  O O   . ARG A 1 36  ? 101.077 70.655 118.618 1.00 0.23 ? 36  ARG A O   1 
ATOM 255  C CB  . ARG A 1 36  ? 100.200 68.476 116.426 1.00 0.23 ? 36  ARG A CB  1 
ATOM 256  C CG  . ARG A 1 36  ? 98.864  69.149 116.810 1.00 0.23 ? 36  ARG A CG  1 
ATOM 257  C CD  . ARG A 1 36  ? 97.836  69.075 115.677 1.00 0.23 ? 36  ARG A CD  1 
ATOM 258  N NE  . ARG A 1 36  ? 96.539  69.648 116.177 1.00 0.23 ? 36  ARG A NE  1 
ATOM 259  C CZ  . ARG A 1 36  ? 96.191  70.940 116.100 1.00 0.23 ? 36  ARG A CZ  1 
ATOM 260  N NH1 . ARG A 1 36  ? 95.028  71.329 116.627 1.00 0.23 ? 36  ARG A NH1 1 
ATOM 261  N NH2 . ARG A 1 36  ? 96.965  71.852 115.526 1.00 0.23 ? 36  ARG A NH2 1 
ATOM 262  N N   . SER A 1 37  ? 102.688 70.475 117.073 1.00 0.30 ? 37  SER A N   1 
ATOM 263  C CA  . SER A 1 37  ? 103.273 71.780 117.345 1.00 0.30 ? 37  SER A CA  1 
ATOM 264  C C   . SER A 1 37  ? 102.521 72.970 116.790 1.00 0.30 ? 37  SER A C   1 
ATOM 265  O O   . SER A 1 37  ? 102.729 74.104 117.213 1.00 0.30 ? 37  SER A O   1 
ATOM 266  C CB  . SER A 1 37  ? 104.683 71.873 116.717 1.00 0.30 ? 37  SER A CB  1 
ATOM 267  O OG  . SER A 1 37  ? 105.457 70.730 117.076 1.00 0.30 ? 37  SER A OG  1 
ATOM 268  N N   . LYS A 1 38  ? 101.652 72.769 115.780 1.00 0.46 ? 38  LYS A N   1 
ATOM 269  C CA  . LYS A 1 38  ? 101.060 73.887 115.076 1.00 0.46 ? 38  LYS A CA  1 
ATOM 270  C C   . LYS A 1 38  ? 99.798  73.453 114.333 1.00 0.46 ? 38  LYS A C   1 
ATOM 271  O O   . LYS A 1 38  ? 99.501  72.265 114.184 1.00 0.46 ? 38  LYS A O   1 
ATOM 272  C CB  . LYS A 1 38  ? 102.102 74.484 114.081 1.00 0.46 ? 38  LYS A CB  1 
ATOM 273  C CG  . LYS A 1 38  ? 101.872 75.939 113.634 1.00 0.46 ? 38  LYS A CG  1 
ATOM 274  C CD  . LYS A 1 38  ? 103.019 76.492 112.763 1.00 0.46 ? 38  LYS A CD  1 
ATOM 275  C CE  . LYS A 1 38  ? 103.163 75.776 111.411 1.00 0.46 ? 38  LYS A CE  1 
ATOM 276  N NZ  . LYS A 1 38  ? 104.307 76.320 110.645 1.00 0.46 ? 38  LYS A NZ  1 
ATOM 277  N N   . GLN A 1 39  ? 98.992  74.427 113.859 1.00 0.51 ? 39  GLN A N   1 
ATOM 278  C CA  . GLN A 1 39  ? 98.032  74.283 112.775 1.00 0.51 ? 39  GLN A CA  1 
ATOM 279  C C   . GLN A 1 39  ? 98.728  74.217 111.411 1.00 0.51 ? 39  GLN A C   1 
ATOM 280  O O   . GLN A 1 39  ? 99.934  74.430 111.313 1.00 0.51 ? 39  GLN A O   1 
ATOM 281  C CB  . GLN A 1 39  ? 97.037  75.472 112.791 1.00 0.51 ? 39  GLN A CB  1 
ATOM 282  C CG  . GLN A 1 39  ? 97.700  76.866 112.648 1.00 0.51 ? 39  GLN A CG  1 
ATOM 283  C CD  . GLN A 1 39  ? 96.655  77.983 112.743 1.00 0.51 ? 39  GLN A CD  1 
ATOM 284  O OE1 . GLN A 1 39  ? 95.454  77.768 112.563 1.00 0.51 ? 39  GLN A OE1 1 
ATOM 285  N NE2 . GLN A 1 39  ? 97.129  79.211 113.046 1.00 0.51 ? 39  GLN A NE2 1 
ATOM 286  N N   . ARG A 1 40  ? 97.982  73.914 110.318 1.00 0.38 ? 40  ARG A N   1 
ATOM 287  C CA  . ARG A 1 40  ? 98.537  73.745 108.975 1.00 0.38 ? 40  ARG A CA  1 
ATOM 288  C C   . ARG A 1 40  ? 99.265  74.974 108.431 1.00 0.38 ? 40  ARG A C   1 
ATOM 289  O O   . ARG A 1 40  ? 100.417 74.889 108.005 1.00 0.38 ? 40  ARG A O   1 
ATOM 290  C CB  . ARG A 1 40  ? 97.397  73.333 107.991 1.00 0.38 ? 40  ARG A CB  1 
ATOM 291  C CG  . ARG A 1 40  ? 97.830  73.000 106.539 1.00 0.38 ? 40  ARG A CG  1 
ATOM 292  C CD  . ARG A 1 40  ? 96.705  72.404 105.662 1.00 0.38 ? 40  ARG A CD  1 
ATOM 293  N NE  . ARG A 1 40  ? 97.264  72.025 104.317 1.00 0.38 ? 40  ARG A NE  1 
ATOM 294  C CZ  . ARG A 1 40  ? 98.006  70.937 104.062 1.00 0.38 ? 40  ARG A CZ  1 
ATOM 295  N NH1 . ARG A 1 40  ? 98.463  70.746 102.828 1.00 0.38 ? 40  ARG A NH1 1 
ATOM 296  N NH2 . ARG A 1 40  ? 98.306  70.049 105.001 1.00 0.38 ? 40  ARG A NH2 1 
ATOM 297  N N   . ARG A 1 41  ? 98.644  76.168 108.508 1.00 0.38 ? 41  ARG A N   1 
ATOM 298  C CA  . ARG A 1 41  ? 99.279  77.414 108.141 1.00 0.38 ? 41  ARG A CA  1 
ATOM 299  C C   . ARG A 1 41  ? 98.687  78.498 109.032 1.00 0.38 ? 41  ARG A C   1 
ATOM 300  O O   . ARG A 1 41  ? 97.554  78.323 109.482 1.00 0.38 ? 41  ARG A O   1 
ATOM 301  C CB  . ARG A 1 41  ? 99.054  77.789 106.650 1.00 0.38 ? 41  ARG A CB  1 
ATOM 302  C CG  . ARG A 1 41  ? 99.985  77.036 105.675 1.00 0.38 ? 41  ARG A CG  1 
ATOM 303  C CD  . ARG A 1 41  ? 99.839  77.450 104.205 1.00 0.38 ? 41  ARG A CD  1 
ATOM 304  N NE  . ARG A 1 41  ? 98.477  77.024 103.731 1.00 0.38 ? 41  ARG A NE  1 
ATOM 305  C CZ  . ARG A 1 41  ? 98.161  75.861 103.142 1.00 0.38 ? 41  ARG A CZ  1 
ATOM 306  N NH1 . ARG A 1 41  ? 96.898  75.614 102.813 1.00 0.38 ? 41  ARG A NH1 1 
ATOM 307  N NH2 . ARG A 1 41  ? 99.063  74.933 102.848 1.00 0.38 ? 41  ARG A NH2 1 
ATOM 308  N N   . PRO A 1 42  ? 99.383  79.585 109.370 1.00 0.47 ? 42  PRO A N   1 
ATOM 309  C CA  . PRO A 1 42  ? 98.791  80.756 110.017 1.00 0.47 ? 42  PRO A CA  1 
ATOM 310  C C   . PRO A 1 42  ? 97.645  81.441 109.284 1.00 0.47 ? 42  PRO A C   1 
ATOM 311  O O   . PRO A 1 42  ? 97.572  81.391 108.058 1.00 0.47 ? 42  PRO A O   1 
ATOM 312  C CB  . PRO A 1 42  ? 99.964  81.742 110.164 1.00 0.47 ? 42  PRO A CB  1 
ATOM 313  C CG  . PRO A 1 42  ? 101.219 80.869 110.117 1.00 0.47 ? 42  PRO A CG  1 
ATOM 314  C CD  . PRO A 1 42  ? 100.819 79.755 109.155 1.00 0.47 ? 42  PRO A CD  1 
ATOM 315  N N   . GLN A 1 43  ? 96.764  82.128 110.038 1.00 0.45 ? 43  GLN A N   1 
ATOM 316  C CA  . GLN A 1 43  ? 95.787  83.078 109.537 1.00 0.45 ? 43  GLN A CA  1 
ATOM 317  C C   . GLN A 1 43  ? 96.428  84.295 108.871 1.00 0.45 ? 43  GLN A C   1 
ATOM 318  O O   . GLN A 1 43  ? 97.537  84.706 109.203 1.00 0.45 ? 43  GLN A O   1 
ATOM 319  C CB  . GLN A 1 43  ? 94.806  83.532 110.655 1.00 0.45 ? 43  GLN A CB  1 
ATOM 320  C CG  . GLN A 1 43  ? 93.789  82.449 111.107 1.00 0.45 ? 43  GLN A CG  1 
ATOM 321  C CD  . GLN A 1 43  ? 94.429  81.286 111.870 1.00 0.45 ? 43  GLN A CD  1 
ATOM 322  O OE1 . GLN A 1 43  ? 95.434  81.434 112.569 1.00 0.45 ? 43  GLN A OE1 1 
ATOM 323  N NE2 . GLN A 1 43  ? 93.849  80.074 111.711 1.00 0.45 ? 43  GLN A NE2 1 
ATOM 324  N N   . GLY A 1 44  ? 95.728  84.895 107.881 1.00 0.40 ? 44  GLY A N   1 
ATOM 325  C CA  . GLY A 1 44  ? 96.224  86.044 107.124 1.00 0.40 ? 44  GLY A CA  1 
ATOM 326  C C   . GLY A 1 44  ? 96.828  85.700 105.790 1.00 0.40 ? 44  GLY A C   1 
ATOM 327  O O   . GLY A 1 44  ? 97.188  86.581 105.016 1.00 0.40 ? 44  GLY A O   1 
ATOM 328  N N   . LEU A 1 45  ? 96.941  84.404 105.466 1.00 0.34 ? 45  LEU A N   1 
ATOM 329  C CA  . LEU A 1 45  ? 97.592  83.945 104.258 1.00 0.34 ? 45  LEU A CA  1 
ATOM 330  C C   . LEU A 1 45  ? 96.551  83.467 103.240 1.00 0.34 ? 45  LEU A C   1 
ATOM 331  O O   . LEU A 1 45  ? 95.602  82.784 103.637 1.00 0.34 ? 45  LEU A O   1 
ATOM 332  C CB  . LEU A 1 45  ? 98.552  82.783 104.613 1.00 0.34 ? 45  LEU A CB  1 
ATOM 333  C CG  . LEU A 1 45  ? 99.692  83.164 105.586 1.00 0.34 ? 45  LEU A CG  1 
ATOM 334  C CD1 . LEU A 1 45  ? 100.469 81.913 106.019 1.00 0.34 ? 45  LEU A CD1 1 
ATOM 335  C CD2 . LEU A 1 45  ? 100.656 84.206 104.992 1.00 0.34 ? 45  LEU A CD2 1 
ATOM 336  N N   . PRO A 1 46  ? 96.615  83.795 101.940 1.00 0.53 ? 46  PRO A N   1 
ATOM 337  C CA  . PRO A 1 46  ? 95.765  83.180 100.936 1.00 0.53 ? 46  PRO A CA  1 
ATOM 338  C C   . PRO A 1 46  ? 96.139  81.748 100.707 1.00 0.53 ? 46  PRO A C   1 
ATOM 339  O O   . PRO A 1 46  ? 97.204  81.305 101.132 1.00 0.53 ? 46  PRO A O   1 
ATOM 340  C CB  . PRO A 1 46  ? 95.988  84.016 99.670  1.00 0.53 ? 46  PRO A CB  1 
ATOM 341  C CG  . PRO A 1 46  ? 97.429  84.514 99.803  1.00 0.53 ? 46  PRO A CG  1 
ATOM 342  C CD  . PRO A 1 46  ? 97.682  84.578 101.319 1.00 0.53 ? 46  PRO A CD  1 
ATOM 343  N N   . ASN A 1 47  ? 95.247  81.006 100.038 1.00 0.52 ? 47  ASN A N   1 
ATOM 344  C CA  . ASN A 1 47  ? 95.490  79.607 99.815  1.00 0.52 ? 47  ASN A CA  1 
ATOM 345  C C   . ASN A 1 47  ? 95.680  79.384 98.342  1.00 0.52 ? 47  ASN A C   1 
ATOM 346  O O   . ASN A 1 47  ? 96.505  78.557 97.962  1.00 0.52 ? 47  ASN A O   1 
ATOM 347  C CB  . ASN A 1 47  ? 94.374  78.730 100.425 1.00 0.52 ? 47  ASN A CB  1 
ATOM 348  C CG  . ASN A 1 47  ? 94.528  78.851 101.937 1.00 0.52 ? 47  ASN A CG  1 
ATOM 349  O OD1 . ASN A 1 47  ? 95.175  78.014 102.572 1.00 0.52 ? 47  ASN A OD1 1 
ATOM 350  N ND2 . ASN A 1 47  ? 93.969  79.930 102.524 1.00 0.52 ? 47  ASN A ND2 1 
ATOM 351  N N   . ASN A 1 48  ? 94.961  80.142 97.470  1.00 0.53 ? 48  ASN A N   1 
ATOM 352  C CA  . ASN A 1 48  ? 94.873  79.757 96.065  1.00 0.53 ? 48  ASN A CA  1 
ATOM 353  C C   . ASN A 1 48  ? 94.308  80.868 95.090  1.00 0.53 ? 48  ASN A C   1 
ATOM 354  O O   . ASN A 1 48  ? 93.978  81.941 95.602  1.00 0.53 ? 48  ASN A O   1 
ATOM 355  C CB  . ASN A 1 48  ? 94.127  78.399 96.117  1.00 0.53 ? 48  ASN A CB  1 
ATOM 356  C CG  . ASN A 1 48  ? 92.714  78.438 96.680  1.00 0.53 ? 48  ASN A CG  1 
ATOM 357  O OD1 . ASN A 1 48  ? 92.048  79.456 96.845  1.00 0.53 ? 48  ASN A OD1 1 
ATOM 358  N ND2 . ASN A 1 48  ? 92.201  77.220 97.007  1.00 0.53 ? 48  ASN A ND2 1 
ATOM 359  N N   . THR A 1 49  ? 94.294  80.712 93.732  1.00 0.44 ? 49  THR A N   1 
ATOM 360  C CA  . THR A 1 49  ? 93.684  81.703 92.738  1.00 0.44 ? 49  THR A CA  1 
ATOM 361  C C   . THR A 1 49  ? 92.309  81.114 92.235  1.00 0.44 ? 49  THR A C   1 
ATOM 362  O O   . THR A 1 49  ? 91.524  80.661 93.000  1.00 0.44 ? 49  THR A O   1 
ATOM 363  C CB  . THR A 1 49  ? 94.581  82.139 91.571  1.00 0.44 ? 49  THR A CB  1 
ATOM 364  O OG1 . THR A 1 49  ? 95.170  81.086 90.842  1.00 0.44 ? 49  THR A OG1 1 
ATOM 365  C CG2 . THR A 1 49  ? 95.672  83.019 92.190  1.00 0.44 ? 49  THR A CG2 1 
ATOM 366  N N   . ALA A 1 50  ? 91.925  81.096 90.931  1.00 0.45 ? 50  ALA A N   1 
ATOM 367  C CA  . ALA A 1 50  ? 90.797  80.300 90.360  1.00 0.45 ? 50  ALA A CA  1 
ATOM 368  C C   . ALA A 1 50  ? 91.182  78.906 89.802  1.00 0.45 ? 50  ALA A C   1 
ATOM 369  O O   . ALA A 1 50  ? 92.327  78.679 89.443  1.00 0.45 ? 50  ALA A O   1 
ATOM 370  C CB  . ALA A 1 50  ? 90.187  81.026 89.145  1.00 0.45 ? 50  ALA A CB  1 
ATOM 371  N N   . SER A 1 51  ? 90.244  77.922 89.630  1.00 0.33 ? 51  SER A N   1 
ATOM 372  C CA  . SER A 1 51  ? 90.483  76.625 88.949  1.00 0.33 ? 51  SER A CA  1 
ATOM 373  C C   . SER A 1 51  ? 89.531  76.564 87.795  1.00 0.33 ? 51  SER A C   1 
ATOM 374  O O   . SER A 1 51  ? 88.629  77.390 87.683  1.00 0.33 ? 51  SER A O   1 
ATOM 375  C CB  . SER A 1 51  ? 90.233  75.328 89.792  1.00 0.33 ? 51  SER A CB  1 
ATOM 376  O OG  . SER A 1 51  ? 90.391  74.066 89.141  1.00 0.33 ? 51  SER A OG  1 
ATOM 377  N N   . TRP A 1 52  ? 89.715  75.583 86.898  1.00 0.38 ? 52  TRP A N   1 
ATOM 378  C CA  . TRP A 1 52  ? 88.785  75.350 85.826  1.00 0.38 ? 52  TRP A CA  1 
ATOM 379  C C   . TRP A 1 52  ? 87.941  74.132 86.132  1.00 0.38 ? 52  TRP A C   1 
ATOM 380  O O   . TRP A 1 52  ? 88.460  73.037 86.351  1.00 0.38 ? 52  TRP A O   1 
ATOM 381  C CB  . TRP A 1 52  ? 89.506  75.170 84.481  1.00 0.38 ? 52  TRP A CB  1 
ATOM 382  C CG  . TRP A 1 52  ? 88.621  75.367 83.270  1.00 0.38 ? 52  TRP A CG  1 
ATOM 383  C CD1 . TRP A 1 52  ? 87.580  74.597 82.822  1.00 0.38 ? 52  TRP A CD1 1 
ATOM 384  C CD2 . TRP A 1 52  ? 88.682  76.497 82.387  1.00 0.38 ? 52  TRP A CD2 1 
ATOM 385  N NE1 . TRP A 1 52  ? 87.112  75.080 81.625  1.00 0.38 ? 52  TRP A NE1 1 
ATOM 386  C CE2 . TRP A 1 52  ? 87.747  76.260 81.364  1.00 0.38 ? 52  TRP A CE2 1 
ATOM 387  C CE3 . TRP A 1 52  ? 89.429  77.674 82.414  1.00 0.38 ? 52  TRP A CE3 1 
ATOM 388  C CZ2 . TRP A 1 52  ? 87.572  77.167 80.344  1.00 0.38 ? 52  TRP A CZ2 1 
ATOM 389  C CZ3 . TRP A 1 52  ? 89.210  78.619 81.398  1.00 0.38 ? 52  TRP A CZ3 1 
ATOM 390  C CH2 . TRP A 1 52  ? 88.299  78.363 80.368  1.00 0.38 ? 52  TRP A CH2 1 
ATOM 391  N N   . PHE A 1 53  ? 86.612  74.320 86.108  1.00 0.55 ? 53  PHE A N   1 
ATOM 392  C CA  . PHE A 1 53  ? 85.624  73.320 86.428  1.00 0.55 ? 53  PHE A CA  1 
ATOM 393  C C   . PHE A 1 53  ? 84.672  73.189 85.252  1.00 0.55 ? 53  PHE A C   1 
ATOM 394  O O   . PHE A 1 53  ? 84.599  74.059 84.385  1.00 0.55 ? 53  PHE A O   1 
ATOM 395  C CB  . PHE A 1 53  ? 84.814  73.713 87.694  1.00 0.55 ? 53  PHE A CB  1 
ATOM 396  C CG  . PHE A 1 53  ? 85.694  73.849 88.909  1.00 0.55 ? 53  PHE A CG  1 
ATOM 397  C CD1 . PHE A 1 53  ? 86.302  72.713 89.457  1.00 0.55 ? 53  PHE A CD1 1 
ATOM 398  C CD2 . PHE A 1 53  ? 85.882  75.088 89.549  1.00 0.55 ? 53  PHE A CD2 1 
ATOM 399  C CE1 . PHE A 1 53  ? 87.097  72.805 90.606  1.00 0.55 ? 53  PHE A CE1 1 
ATOM 400  C CE2 . PHE A 1 53  ? 86.659  75.181 90.711  1.00 0.55 ? 53  PHE A CE2 1 
ATOM 401  C CZ  . PHE A 1 53  ? 87.270  74.037 91.237  1.00 0.55 ? 53  PHE A CZ  1 
ATOM 402  N N   . THR A 1 54  ? 83.952  72.050 85.182  1.00 0.60 ? 54  THR A N   1 
ATOM 403  C CA  . THR A 1 54  ? 82.947  71.742 84.161  1.00 0.60 ? 54  THR A CA  1 
ATOM 404  C C   . THR A 1 54  ? 81.672  72.582 84.283  1.00 0.60 ? 54  THR A C   1 
ATOM 405  O O   . THR A 1 54  ? 81.325  73.002 85.383  1.00 0.60 ? 54  THR A O   1 
ATOM 406  C CB  . THR A 1 54  ? 82.552  70.263 84.183  1.00 0.60 ? 54  THR A CB  1 
ATOM 407  O OG1 . THR A 1 54  ? 83.659  69.393 84.283  1.00 0.60 ? 54  THR A OG1 1 
ATOM 408  C CG2 . THR A 1 54  ? 81.896  69.860 82.866  1.00 0.60 ? 54  THR A CG2 1 
ATOM 409  N N   . ALA A 1 55  ? 80.932  72.870 83.177  1.00 0.60 ? 55  ALA A N   1 
ATOM 410  C CA  . ALA A 1 55  ? 79.813  73.815 83.172  1.00 0.60 ? 55  ALA A CA  1 
ATOM 411  C C   . ALA A 1 55  ? 78.500  73.312 82.550  1.00 0.60 ? 55  ALA A C   1 
ATOM 412  O O   . ALA A 1 55  ? 78.475  72.823 81.425  1.00 0.60 ? 55  ALA A O   1 
ATOM 413  C CB  . ALA A 1 55  ? 80.241  75.084 82.409  1.00 0.60 ? 55  ALA A CB  1 
ATOM 414  N N   . LEU A 1 56  ? 77.370  73.486 83.275  1.00 0.62 ? 56  LEU A N   1 
ATOM 415  C CA  . LEU A 1 56  ? 76.064  72.868 83.034  1.00 0.62 ? 56  LEU A CA  1 
ATOM 416  C C   . LEU A 1 56  ? 75.008  73.921 82.677  1.00 0.62 ? 56  LEU A C   1 
ATOM 417  O O   . LEU A 1 56  ? 75.176  75.093 83.002  1.00 0.62 ? 56  LEU A O   1 
ATOM 418  C CB  . LEU A 1 56  ? 75.704  72.103 84.342  1.00 0.62 ? 56  LEU A CB  1 
ATOM 419  C CG  . LEU A 1 56  ? 74.299  71.474 84.500  1.00 0.62 ? 56  LEU A CG  1 
ATOM 420  C CD1 . LEU A 1 56  ? 74.399  70.179 85.318  1.00 0.62 ? 56  LEU A CD1 1 
ATOM 421  C CD2 . LEU A 1 56  ? 73.271  72.404 85.177  1.00 0.62 ? 56  LEU A CD2 1 
ATOM 422  N N   . THR A 1 57  ? 73.892  73.555 81.990  1.00 0.61 ? 57  THR A N   1 
ATOM 423  C CA  . THR A 1 57  ? 72.847  74.516 81.589  1.00 0.61 ? 57  THR A CA  1 
ATOM 424  C C   . THR A 1 57  ? 71.479  73.842 81.596  1.00 0.61 ? 57  THR A C   1 
ATOM 425  O O   . THR A 1 57  ? 71.318  72.707 81.162  1.00 0.61 ? 57  THR A O   1 
ATOM 426  C CB  . THR A 1 57  ? 73.088  75.137 80.203  1.00 0.61 ? 57  THR A CB  1 
ATOM 427  O OG1 . THR A 1 57  ? 74.208  76.008 80.229  1.00 0.61 ? 57  THR A OG1 1 
ATOM 428  C CG2 . THR A 1 57  ? 71.930  76.006 79.682  1.00 0.61 ? 57  THR A CG2 1 
ATOM 429  N N   . GLN A 1 58  ? 70.421  74.510 82.111  1.00 0.57 ? 58  GLN A N   1 
ATOM 430  C CA  . GLN A 1 58  ? 69.104  73.899 82.268  1.00 0.57 ? 58  GLN A CA  1 
ATOM 431  C C   . GLN A 1 58  ? 68.171  73.775 81.071  1.00 0.57 ? 58  GLN A C   1 
ATOM 432  O O   . GLN A 1 58  ? 67.504  72.756 80.963  1.00 0.57 ? 58  GLN A O   1 
ATOM 433  C CB  . GLN A 1 58  ? 68.292  74.584 83.384  1.00 0.57 ? 58  GLN A CB  1 
ATOM 434  C CG  . GLN A 1 58  ? 68.727  74.147 84.789  1.00 0.57 ? 58  GLN A CG  1 
ATOM 435  C CD  . GLN A 1 58  ? 67.546  74.245 85.746  1.00 0.57 ? 58  GLN A CD  1 
ATOM 436  O OE1 . GLN A 1 58  ? 67.401  75.176 86.539  1.00 0.57 ? 58  GLN A OE1 1 
ATOM 437  N NE2 . GLN A 1 58  ? 66.652  73.237 85.651  1.00 0.57 ? 58  GLN A NE2 1 
ATOM 438  N N   . HIS A 1 59  ? 68.024  74.813 80.219  1.00 0.52 ? 59  HIS A N   1 
ATOM 439  C CA  . HIS A 1 59  ? 66.966  74.890 79.204  1.00 0.52 ? 59  HIS A CA  1 
ATOM 440  C C   . HIS A 1 59  ? 65.555  74.783 79.801  1.00 0.52 ? 59  HIS A C   1 
ATOM 441  O O   . HIS A 1 59  ? 64.676  74.114 79.264  1.00 0.52 ? 59  HIS A O   1 
ATOM 442  C CB  . HIS A 1 59  ? 67.152  73.848 78.075  1.00 0.52 ? 59  HIS A CB  1 
ATOM 443  C CG  . HIS A 1 59  ? 68.506  73.863 77.426  1.00 0.52 ? 59  HIS A CG  1 
ATOM 444  N ND1 . HIS A 1 59  ? 68.579  74.280 76.121  1.00 0.52 ? 59  HIS A ND1 1 
ATOM 445  C CD2 . HIS A 1 59  ? 69.729  73.427 77.836  1.00 0.52 ? 59  HIS A CD2 1 
ATOM 446  C CE1 . HIS A 1 59  ? 69.815  74.090 75.746  1.00 0.52 ? 59  HIS A CE1 1 
ATOM 447  N NE2 . HIS A 1 59  ? 70.567  73.579 76.748  1.00 0.52 ? 59  HIS A NE2 1 
ATOM 448  N N   . GLY A 1 60  ? 65.310  75.416 80.971  1.00 0.54 ? 60  GLY A N   1 
ATOM 449  C CA  . GLY A 1 60  ? 64.059  75.219 81.688  1.00 0.54 ? 60  GLY A CA  1 
ATOM 450  C C   . GLY A 1 60  ? 64.099  75.708 83.116  1.00 0.54 ? 60  GLY A C   1 
ATOM 451  O O   . GLY A 1 60  ? 64.913  76.559 83.478  1.00 0.54 ? 60  GLY A O   1 
ATOM 452  N N   . LYS A 1 61  ? 63.204  75.165 83.983  1.00 0.54 ? 61  LYS A N   1 
ATOM 453  C CA  . LYS A 1 61  ? 62.958  75.710 85.309  1.00 0.54 ? 61  LYS A CA  1 
ATOM 454  C C   . LYS A 1 61  ? 62.728  74.668 86.402  1.00 0.54 ? 61  LYS A C   1 
ATOM 455  O O   . LYS A 1 61  ? 62.314  75.018 87.503  1.00 0.54 ? 61  LYS A O   1 
ATOM 456  C CB  . LYS A 1 61  ? 61.692  76.617 85.267  1.00 0.54 ? 61  LYS A CB  1 
ATOM 457  C CG  . LYS A 1 61  ? 60.374  75.888 84.921  1.00 0.54 ? 61  LYS A CG  1 
ATOM 458  C CD  . LYS A 1 61  ? 59.160  76.829 84.782  1.00 0.54 ? 61  LYS A CD  1 
ATOM 459  C CE  . LYS A 1 61  ? 58.744  77.514 86.091  1.00 0.54 ? 61  LYS A CE  1 
ATOM 460  N NZ  . LYS A 1 61  ? 57.536  78.351 85.881  1.00 0.54 ? 61  LYS A NZ  1 
ATOM 461  N N   . GLU A 1 62  ? 62.977  73.372 86.121  1.00 0.55 ? 62  GLU A N   1 
ATOM 462  C CA  . GLU A 1 62  ? 62.903  72.273 87.080  1.00 0.55 ? 62  GLU A CA  1 
ATOM 463  C C   . GLU A 1 62  ? 64.037  72.280 88.106  1.00 0.55 ? 62  GLU A C   1 
ATOM 464  O O   . GLU A 1 62  ? 65.125  72.780 87.831  1.00 0.55 ? 62  GLU A O   1 
ATOM 465  C CB  . GLU A 1 62  ? 62.858  70.932 86.310  1.00 0.55 ? 62  GLU A CB  1 
ATOM 466  C CG  . GLU A 1 62  ? 62.627  69.671 87.176  1.00 0.55 ? 62  GLU A CG  1 
ATOM 467  C CD  . GLU A 1 62  ? 62.144  68.484 86.346  1.00 0.55 ? 62  GLU A CD  1 
ATOM 468  O OE1 . GLU A 1 62  ? 62.480  68.422 85.133  1.00 0.55 ? 62  GLU A OE1 1 
ATOM 469  O OE2 . GLU A 1 62  ? 61.437  67.626 86.930  1.00 0.55 ? 62  GLU A OE2 1 
ATOM 470  N N   . ASP A 1 63  ? 63.834  71.752 89.332  1.00 0.51 ? 63  ASP A N   1 
ATOM 471  C CA  . ASP A 1 63  ? 64.873  71.697 90.345  1.00 0.51 ? 63  ASP A CA  1 
ATOM 472  C C   . ASP A 1 63  ? 66.080  70.831 89.962  1.00 0.51 ? 63  ASP A C   1 
ATOM 473  O O   . ASP A 1 63  ? 65.955  69.690 89.522  1.00 0.51 ? 63  ASP A O   1 
ATOM 474  C CB  . ASP A 1 63  ? 64.361  71.147 91.702  1.00 0.51 ? 63  ASP A CB  1 
ATOM 475  C CG  . ASP A 1 63  ? 63.326  72.017 92.407  1.00 0.51 ? 63  ASP A CG  1 
ATOM 476  O OD1 . ASP A 1 63  ? 62.995  73.128 91.946  1.00 0.51 ? 63  ASP A OD1 1 
ATOM 477  O OD2 . ASP A 1 63  ? 62.896  71.549 93.498  1.00 0.51 ? 63  ASP A OD2 1 
ATOM 478  N N   . LEU A 1 64  ? 67.312  71.333 90.192  1.00 0.57 ? 64  LEU A N   1 
ATOM 479  C CA  . LEU A 1 64  ? 68.522  70.525 90.104  1.00 0.57 ? 64  LEU A CA  1 
ATOM 480  C C   . LEU A 1 64  ? 68.668  69.643 91.349  1.00 0.57 ? 64  LEU A C   1 
ATOM 481  O O   . LEU A 1 64  ? 69.312  70.014 92.329  1.00 0.57 ? 64  LEU A O   1 
ATOM 482  C CB  . LEU A 1 64  ? 69.774  71.427 89.930  1.00 0.57 ? 64  LEU A CB  1 
ATOM 483  C CG  . LEU A 1 64  ? 71.104  70.683 89.668  1.00 0.57 ? 64  LEU A CG  1 
ATOM 484  C CD1 . LEU A 1 64  ? 71.304  70.329 88.193  1.00 0.57 ? 64  LEU A CD1 1 
ATOM 485  C CD2 . LEU A 1 64  ? 72.315  71.498 90.125  1.00 0.57 ? 64  LEU A CD2 1 
ATOM 486  N N   . LYS A 1 65  ? 68.031  68.454 91.353  1.00 0.52 ? 65  LYS A N   1 
ATOM 487  C CA  . LYS A 1 65  ? 67.970  67.578 92.508  1.00 0.52 ? 65  LYS A CA  1 
ATOM 488  C C   . LYS A 1 65  ? 68.195  66.130 92.121  1.00 0.52 ? 65  LYS A C   1 
ATOM 489  O O   . LYS A 1 65  ? 68.042  65.742 90.966  1.00 0.52 ? 65  LYS A O   1 
ATOM 490  C CB  . LYS A 1 65  ? 66.595  67.705 93.214  1.00 0.52 ? 65  LYS A CB  1 
ATOM 491  C CG  . LYS A 1 65  ? 66.506  68.955 94.101  1.00 0.52 ? 65  LYS A CG  1 
ATOM 492  C CD  . LYS A 1 65  ? 65.107  69.168 94.703  1.00 0.52 ? 65  LYS A CD  1 
ATOM 493  C CE  . LYS A 1 65  ? 65.028  70.444 95.551  1.00 0.52 ? 65  LYS A CE  1 
ATOM 494  N NZ  . LYS A 1 65  ? 63.624  70.809 95.820  1.00 0.52 ? 65  LYS A NZ  1 
ATOM 495  N N   . PHE A 1 66  ? 68.583  65.298 93.112  1.00 0.46 ? 66  PHE A N   1 
ATOM 496  C CA  . PHE A 1 66  ? 69.031  63.939 92.899  1.00 0.46 ? 66  PHE A CA  1 
ATOM 497  C C   . PHE A 1 66  ? 68.537  63.074 94.063  1.00 0.46 ? 66  PHE A C   1 
ATOM 498  O O   . PHE A 1 66  ? 68.183  63.629 95.107  1.00 0.46 ? 66  PHE A O   1 
ATOM 499  C CB  . PHE A 1 66  ? 70.581  63.864 92.909  1.00 0.46 ? 66  PHE A CB  1 
ATOM 500  C CG  . PHE A 1 66  ? 71.220  64.634 91.785  1.00 0.46 ? 66  PHE A CG  1 
ATOM 501  C CD1 . PHE A 1 66  ? 71.483  64.007 90.559  1.00 0.46 ? 66  PHE A CD1 1 
ATOM 502  C CD2 . PHE A 1 66  ? 71.635  65.964 91.969  1.00 0.46 ? 66  PHE A CD2 1 
ATOM 503  C CE1 . PHE A 1 66  ? 72.162  64.687 89.542  1.00 0.46 ? 66  PHE A CE1 1 
ATOM 504  C CE2 . PHE A 1 66  ? 72.299  66.654 90.949  1.00 0.46 ? 66  PHE A CE2 1 
ATOM 505  C CZ  . PHE A 1 66  ? 72.574  66.009 89.737  1.00 0.46 ? 66  PHE A CZ  1 
ATOM 506  N N   . PRO A 1 67  ? 68.480  61.742 93.964  1.00 0.44 ? 67  PRO A N   1 
ATOM 507  C CA  . PRO A 1 67  ? 68.428  60.822 95.106  1.00 0.44 ? 67  PRO A CA  1 
ATOM 508  C C   . PRO A 1 67  ? 69.516  60.980 96.166  1.00 0.44 ? 67  PRO A C   1 
ATOM 509  O O   . PRO A 1 67  ? 70.464  61.743 96.005  1.00 0.44 ? 67  PRO A O   1 
ATOM 510  C CB  . PRO A 1 67  ? 68.490  59.421 94.466  1.00 0.44 ? 67  PRO A CB  1 
ATOM 511  C CG  . PRO A 1 67  ? 68.014  59.631 93.029  1.00 0.44 ? 67  PRO A CG  1 
ATOM 512  C CD  . PRO A 1 67  ? 68.558  61.016 92.700  1.00 0.44 ? 67  PRO A CD  1 
ATOM 513  N N   . ARG A 1 68  ? 69.402  60.234 97.289  1.00 0.44 ? 68  ARG A N   1 
ATOM 514  C CA  . ARG A 1 68  ? 70.378  60.237 98.374  1.00 0.44 ? 68  ARG A CA  1 
ATOM 515  C C   . ARG A 1 68  ? 71.772  59.741 97.977  1.00 0.44 ? 68  ARG A C   1 
ATOM 516  O O   . ARG A 1 68  ? 72.789  60.246 98.450  1.00 0.44 ? 68  ARG A O   1 
ATOM 517  C CB  . ARG A 1 68  ? 69.842  59.431 99.593  1.00 0.44 ? 68  ARG A CB  1 
ATOM 518  C CG  . ARG A 1 68  ? 68.456  59.878 100.123 1.00 0.44 ? 68  ARG A CG  1 
ATOM 519  C CD  . ARG A 1 68  ? 68.319  61.364 100.504 1.00 0.44 ? 68  ARG A CD  1 
ATOM 520  N NE  . ARG A 1 68  ? 69.247  61.640 101.661 1.00 0.44 ? 68  ARG A NE  1 
ATOM 521  C CZ  . ARG A 1 68  ? 69.821  62.823 101.935 1.00 0.44 ? 68  ARG A CZ  1 
ATOM 522  N NH1 . ARG A 1 68  ? 70.580  62.963 103.025 1.00 0.44 ? 68  ARG A NH1 1 
ATOM 523  N NH2 . ARG A 1 68  ? 69.659  63.870 101.134 1.00 0.44 ? 68  ARG A NH2 1 
ATOM 524  N N   . GLY A 1 69  ? 71.845  58.724 97.094  1.00 0.53 ? 69  GLY A N   1 
ATOM 525  C CA  . GLY A 1 69  ? 73.093  58.248 96.513  1.00 0.53 ? 69  GLY A CA  1 
ATOM 526  C C   . GLY A 1 69  ? 73.390  58.925 95.201  1.00 0.53 ? 69  GLY A C   1 
ATOM 527  O O   . GLY A 1 69  ? 72.481  59.282 94.459  1.00 0.53 ? 69  GLY A O   1 
ATOM 528  N N   . GLN A 1 70  ? 74.694  59.095 94.892  1.00 0.55 ? 70  GLN A N   1 
ATOM 529  C CA  . GLN A 1 70  ? 75.213  59.665 93.651  1.00 0.55 ? 70  GLN A CA  1 
ATOM 530  C C   . GLN A 1 70  ? 74.775  61.096 93.348  1.00 0.55 ? 70  GLN A C   1 
ATOM 531  O O   . GLN A 1 70  ? 74.791  61.549 92.208  1.00 0.55 ? 70  GLN A O   1 
ATOM 532  C CB  . GLN A 1 70  ? 75.009  58.715 92.446  1.00 0.55 ? 70  GLN A CB  1 
ATOM 533  C CG  . GLN A 1 70  ? 75.755  57.371 92.626  1.00 0.55 ? 70  GLN A CG  1 
ATOM 534  C CD  . GLN A 1 70  ? 75.602  56.450 91.414  1.00 0.55 ? 70  GLN A CD  1 
ATOM 535  O OE1 . GLN A 1 70  ? 74.819  56.707 90.502  1.00 0.55 ? 70  GLN A OE1 1 
ATOM 536  N NE2 . GLN A 1 70  ? 76.358  55.326 91.433  1.00 0.55 ? 70  GLN A NE2 1 
ATOM 537  N N   . GLY A 1 71  ? 74.450  61.879 94.398  1.00 0.57 ? 71  GLY A N   1 
ATOM 538  C CA  . GLY A 1 71  ? 73.932  63.238 94.262  1.00 0.57 ? 71  GLY A CA  1 
ATOM 539  C C   . GLY A 1 71  ? 74.929  64.322 93.961  1.00 0.57 ? 71  GLY A C   1 
ATOM 540  O O   . GLY A 1 71  ? 74.558  65.480 93.802  1.00 0.57 ? 71  GLY A O   1 
ATOM 541  N N   . VAL A 1 72  ? 76.227  63.989 93.878  1.00 0.66 ? 72  VAL A N   1 
ATOM 542  C CA  . VAL A 1 72  ? 77.259  64.934 93.494  1.00 0.66 ? 72  VAL A CA  1 
ATOM 543  C C   . VAL A 1 72  ? 78.363  64.156 92.767  1.00 0.66 ? 72  VAL A C   1 
ATOM 544  O O   . VAL A 1 72  ? 78.545  62.982 93.106  1.00 0.66 ? 72  VAL A O   1 
ATOM 545  C CB  . VAL A 1 72  ? 77.787  65.732 94.696  1.00 0.66 ? 72  VAL A CB  1 
ATOM 546  C CG1 . VAL A 1 72  ? 78.535  64.836 95.708  1.00 0.66 ? 72  VAL A CG1 1 
ATOM 547  C CG2 . VAL A 1 72  ? 78.648  66.925 94.242  1.00 0.66 ? 72  VAL A CG2 1 
ATOM 548  N N   . PRO A 1 73  ? 79.104  64.666 91.770  1.00 0.65 ? 73  PRO A N   1 
ATOM 549  C CA  . PRO A 1 73  ? 80.105  63.878 91.047  1.00 0.65 ? 73  PRO A CA  1 
ATOM 550  C C   . PRO A 1 73  ? 81.384  63.555 91.811  1.00 0.65 ? 73  PRO A C   1 
ATOM 551  O O   . PRO A 1 73  ? 81.846  64.365 92.615  1.00 0.65 ? 73  PRO A O   1 
ATOM 552  C CB  . PRO A 1 73  ? 80.472  64.744 89.829  1.00 0.65 ? 73  PRO A CB  1 
ATOM 553  C CG  . PRO A 1 73  ? 79.250  65.629 89.607  1.00 0.65 ? 73  PRO A CG  1 
ATOM 554  C CD  . PRO A 1 73  ? 78.768  65.887 91.031  1.00 0.65 ? 73  PRO A CD  1 
ATOM 555  N N   . ILE A 1 74  ? 81.990  62.382 91.521  1.00 0.58 ? 74  ILE A N   1 
ATOM 556  C CA  . ILE A 1 74  ? 83.302  61.956 91.996  1.00 0.58 ? 74  ILE A CA  1 
ATOM 557  C C   . ILE A 1 74  ? 84.050  61.449 90.764  1.00 0.58 ? 74  ILE A C   1 
ATOM 558  O O   . ILE A 1 74  ? 83.505  60.654 89.999  1.00 0.58 ? 74  ILE A O   1 
ATOM 559  C CB  . ILE A 1 74  ? 83.210  60.831 93.035  1.00 0.58 ? 74  ILE A CB  1 
ATOM 560  C CG1 . ILE A 1 74  ? 82.528  61.301 94.347  1.00 0.58 ? 74  ILE A CG1 1 
ATOM 561  C CG2 . ILE A 1 74  ? 84.592  60.198 93.324  1.00 0.58 ? 74  ILE A CG2 1 
ATOM 562  C CD1 . ILE A 1 74  ? 83.354  62.286 95.182  1.00 0.58 ? 74  ILE A CD1 1 
ATOM 563  N N   . ASN A 1 75  ? 85.305  61.889 90.513  1.00 0.49 ? 75  ASN A N   1 
ATOM 564  C CA  . ASN A 1 75  ? 86.084  61.489 89.354  1.00 0.49 ? 75  ASN A CA  1 
ATOM 565  C C   . ASN A 1 75  ? 87.556  61.457 89.771  1.00 0.49 ? 75  ASN A C   1 
ATOM 566  O O   . ASN A 1 75  ? 87.924  62.041 90.782  1.00 0.49 ? 75  ASN A O   1 
ATOM 567  C CB  . ASN A 1 75  ? 85.897  62.464 88.151  1.00 0.49 ? 75  ASN A CB  1 
ATOM 568  C CG  . ASN A 1 75  ? 84.499  62.365 87.547  1.00 0.49 ? 75  ASN A CG  1 
ATOM 569  O OD1 . ASN A 1 75  ? 83.665  63.264 87.654  1.00 0.49 ? 75  ASN A OD1 1 
ATOM 570  N ND2 . ASN A 1 75  ? 84.207  61.242 86.849  1.00 0.49 ? 75  ASN A ND2 1 
ATOM 571  N N   . THR A 1 76  ? 88.454  60.780 89.006  1.00 0.43 ? 76  THR A N   1 
ATOM 572  C CA  . THR A 1 76  ? 89.852  60.488 89.402  1.00 0.43 ? 76  THR A CA  1 
ATOM 573  C C   . THR A 1 76  ? 90.686  61.676 89.859  1.00 0.43 ? 76  THR A C   1 
ATOM 574  O O   . THR A 1 76  ? 91.498  61.555 90.773  1.00 0.43 ? 76  THR A O   1 
ATOM 575  C CB  . THR A 1 76  ? 90.636  59.780 88.274  1.00 0.43 ? 76  THR A CB  1 
ATOM 576  O OG1 . THR A 1 76  ? 90.255  58.419 88.115  1.00 0.43 ? 76  THR A OG1 1 
ATOM 577  C CG2 . THR A 1 76  ? 92.160  59.690 88.468  1.00 0.43 ? 76  THR A CG2 1 
ATOM 578  N N   . ASN A 1 77  ? 90.532  62.862 89.242  1.00 0.56 ? 77  ASN A N   1 
ATOM 579  C CA  . ASN A 1 77  ? 91.279  64.040 89.639  1.00 0.56 ? 77  ASN A CA  1 
ATOM 580  C C   . ASN A 1 77  ? 90.499  65.010 90.520  1.00 0.56 ? 77  ASN A C   1 
ATOM 581  O O   . ASN A 1 77  ? 91.050  66.033 90.917  1.00 0.56 ? 77  ASN A O   1 
ATOM 582  C CB  . ASN A 1 77  ? 91.709  64.820 88.372  1.00 0.56 ? 77  ASN A CB  1 
ATOM 583  C CG  . ASN A 1 77  ? 92.741  64.019 87.594  1.00 0.56 ? 77  ASN A CG  1 
ATOM 584  O OD1 . ASN A 1 77  ? 92.493  63.416 86.548  1.00 0.56 ? 77  ASN A OD1 1 
ATOM 585  N ND2 . ASN A 1 77  ? 93.983  63.998 88.126  1.00 0.56 ? 77  ASN A ND2 1 
ATOM 586  N N   . SER A 1 78  ? 89.212  64.750 90.848  1.00 0.62 ? 78  SER A N   1 
ATOM 587  C CA  . SER A 1 78  ? 88.395  65.726 91.560  1.00 0.62 ? 78  SER A CA  1 
ATOM 588  C C   . SER A 1 78  ? 88.713  65.892 93.035  1.00 0.62 ? 78  SER A C   1 
ATOM 589  O O   . SER A 1 78  ? 88.802  67.011 93.541  1.00 0.62 ? 78  SER A O   1 
ATOM 590  C CB  . SER A 1 78  ? 86.859  65.508 91.371  1.00 0.62 ? 78  SER A CB  1 
ATOM 591  O OG  . SER A 1 78  ? 86.381  64.248 91.843  1.00 0.62 ? 78  SER A OG  1 
ATOM 592  N N   . SER A 1 79  ? 88.883  64.791 93.786  1.00 0.57 ? 79  SER A N   1 
ATOM 593  C CA  . SER A 1 79  ? 88.820  64.881 95.231  1.00 0.57 ? 79  SER A CA  1 
ATOM 594  C C   . SER A 1 79  ? 89.262  63.570 95.871  1.00 0.57 ? 79  SER A C   1 
ATOM 595  O O   . SER A 1 79  ? 89.312  62.561 95.171  1.00 0.57 ? 79  SER A O   1 
ATOM 596  C CB  . SER A 1 79  ? 87.391  65.297 95.687  1.00 0.57 ? 79  SER A CB  1 
ATOM 597  O OG  . SER A 1 79  ? 86.358  64.602 94.988  1.00 0.57 ? 79  SER A OG  1 
ATOM 598  N N   . PRO A 1 80  ? 89.622  63.481 97.157  1.00 0.39 ? 80  PRO A N   1 
ATOM 599  C CA  . PRO A 1 80  ? 90.197  62.256 97.721  1.00 0.39 ? 80  PRO A CA  1 
ATOM 600  C C   . PRO A 1 80  ? 89.106  61.343 98.273  1.00 0.39 ? 80  PRO A C   1 
ATOM 601  O O   . PRO A 1 80  ? 88.991  61.207 99.489  1.00 0.39 ? 80  PRO A O   1 
ATOM 602  C CB  . PRO A 1 80  ? 91.082  62.800 98.870  1.00 0.39 ? 80  PRO A CB  1 
ATOM 603  C CG  . PRO A 1 80  ? 90.361  64.068 99.338  1.00 0.39 ? 80  PRO A CG  1 
ATOM 604  C CD  . PRO A 1 80  ? 89.793  64.637 98.042  1.00 0.39 ? 80  PRO A CD  1 
ATOM 605  N N   . ASP A 1 81  ? 88.289  60.735 97.385  1.00 0.49 ? 81  ASP A N   1 
ATOM 606  C CA  . ASP A 1 81  ? 87.159  59.867 97.696  1.00 0.49 ? 81  ASP A CA  1 
ATOM 607  C C   . ASP A 1 81  ? 86.138  60.538 98.628  1.00 0.49 ? 81  ASP A C   1 
ATOM 608  O O   . ASP A 1 81  ? 85.554  59.936 99.527  1.00 0.49 ? 81  ASP A O   1 
ATOM 609  C CB  . ASP A 1 81  ? 87.611  58.454 98.168  1.00 0.49 ? 81  ASP A CB  1 
ATOM 610  C CG  . ASP A 1 81  ? 88.499  57.764 97.140  1.00 0.49 ? 81  ASP A CG  1 
ATOM 611  O OD1 . ASP A 1 81  ? 88.494  58.186 95.953  1.00 0.49 ? 81  ASP A OD1 1 
ATOM 612  O OD2 . ASP A 1 81  ? 89.178  56.781 97.533  1.00 0.49 ? 81  ASP A OD2 1 
ATOM 613  N N   . ASP A 1 82  ? 85.891  61.843 98.387  1.00 0.52 ? 82  ASP A N   1 
ATOM 614  C CA  . ASP A 1 82  ? 85.208  62.728 99.300  1.00 0.52 ? 82  ASP A CA  1 
ATOM 615  C C   . ASP A 1 82  ? 84.695  63.898 98.462  1.00 0.52 ? 82  ASP A C   1 
ATOM 616  O O   . ASP A 1 82  ? 85.073  64.034 97.296  1.00 0.52 ? 82  ASP A O   1 
ATOM 617  C CB  . ASP A 1 82  ? 86.210  63.199 100.389 1.00 0.52 ? 82  ASP A CB  1 
ATOM 618  C CG  . ASP A 1 82  ? 85.534  63.949 101.515 1.00 0.52 ? 82  ASP A CG  1 
ATOM 619  O OD1 . ASP A 1 82  ? 84.276  64.004 101.544 1.00 0.52 ? 82  ASP A OD1 1 
ATOM 620  O OD2 . ASP A 1 82  ? 86.262  64.481 102.383 1.00 0.52 ? 82  ASP A OD2 1 
ATOM 621  N N   . GLN A 1 83  ? 83.824  64.782 98.985  1.00 0.62 ? 83  GLN A N   1 
ATOM 622  C CA  . GLN A 1 83  ? 83.391  65.931 98.215  1.00 0.62 ? 83  GLN A CA  1 
ATOM 623  C C   . GLN A 1 83  ? 82.898  67.104 99.050  1.00 0.62 ? 83  GLN A C   1 
ATOM 624  O O   . GLN A 1 83  ? 81.932  66.981 99.794  1.00 0.62 ? 83  GLN A O   1 
ATOM 625  C CB  . GLN A 1 83  ? 82.281  65.536 97.200  1.00 0.62 ? 83  GLN A CB  1 
ATOM 626  C CG  . GLN A 1 83  ? 81.930  66.605 96.143  1.00 0.62 ? 83  GLN A CG  1 
ATOM 627  C CD  . GLN A 1 83  ? 83.152  66.991 95.313  1.00 0.62 ? 83  GLN A CD  1 
ATOM 628  O OE1 . GLN A 1 83  ? 84.005  67.775 95.746  1.00 0.62 ? 83  GLN A OE1 1 
ATOM 629  N NE2 . GLN A 1 83  ? 83.263  66.436 94.087  1.00 0.62 ? 83  GLN A NE2 1 
ATOM 630  N N   . ILE A 1 84  ? 83.526  68.301 98.902  1.00 0.60 ? 84  ILE A N   1 
ATOM 631  C CA  . ILE A 1 84  ? 83.011  69.542 99.481  1.00 0.60 ? 84  ILE A CA  1 
ATOM 632  C C   . ILE A 1 84  ? 82.732  70.578 98.395  1.00 0.60 ? 84  ILE A C   1 
ATOM 633  O O   . ILE A 1 84  ? 82.450  71.746 98.676  1.00 0.60 ? 84  ILE A O   1 
ATOM 634  C CB  . ILE A 1 84  ? 83.885  70.129 100.603 1.00 0.60 ? 84  ILE A CB  1 
ATOM 635  C CG1 . ILE A 1 84  ? 85.240  70.705 100.122 1.00 0.60 ? 84  ILE A CG1 1 
ATOM 636  C CG2 . ILE A 1 84  ? 84.054  69.040 101.686 1.00 0.60 ? 84  ILE A CG2 1 
ATOM 637  C CD1 . ILE A 1 84  ? 86.099  71.313 101.243 1.00 0.60 ? 84  ILE A CD1 1 
ATOM 638  N N   . GLY A 1 85  ? 82.787  70.164 97.107  1.00 0.64 ? 85  GLY A N   1 
ATOM 639  C CA  . GLY A 1 85  ? 82.332  70.948 95.967  1.00 0.64 ? 85  GLY A CA  1 
ATOM 640  C C   . GLY A 1 85  ? 80.882  70.705 95.656  1.00 0.64 ? 85  GLY A C   1 
ATOM 641  O O   . GLY A 1 85  ? 80.399  69.579 95.713  1.00 0.64 ? 85  GLY A O   1 
ATOM 642  N N   . TYR A 1 86  ? 80.149  71.765 95.281  1.00 0.61 ? 86  TYR A N   1 
ATOM 643  C CA  . TYR A 1 86  ? 78.716  71.720 95.081  1.00 0.61 ? 86  TYR A CA  1 
ATOM 644  C C   . TYR A 1 86  ? 78.349  72.514 93.845  1.00 0.61 ? 86  TYR A C   1 
ATOM 645  O O   . TYR A 1 86  ? 79.063  73.426 93.430  1.00 0.61 ? 86  TYR A O   1 
ATOM 646  C CB  . TYR A 1 86  ? 77.958  72.386 96.258  1.00 0.61 ? 86  TYR A CB  1 
ATOM 647  C CG  . TYR A 1 86  ? 78.018  71.544 97.497  1.00 0.61 ? 86  TYR A CG  1 
ATOM 648  C CD1 . TYR A 1 86  ? 79.135  71.593 98.341  1.00 0.61 ? 86  TYR A CD1 1 
ATOM 649  C CD2 . TYR A 1 86  ? 76.946  70.711 97.847  1.00 0.61 ? 86  TYR A CD2 1 
ATOM 650  C CE1 . TYR A 1 86  ? 79.187  70.815 99.501  1.00 0.61 ? 86  TYR A CE1 1 
ATOM 651  C CE2 . TYR A 1 86  ? 76.972  69.975 99.042  1.00 0.61 ? 86  TYR A CE2 1 
ATOM 652  C CZ  . TYR A 1 86  ? 78.100  70.024 99.870  1.00 0.61 ? 86  TYR A CZ  1 
ATOM 653  O OH  . TYR A 1 86  ? 78.197  69.330 101.093 1.00 0.61 ? 86  TYR A OH  1 
ATOM 654  N N   . TYR A 1 87  ? 77.200  72.182 93.219  1.00 0.64 ? 87  TYR A N   1 
ATOM 655  C CA  . TYR A 1 87  ? 76.647  72.931 92.104  1.00 0.64 ? 87  TYR A CA  1 
ATOM 656  C C   . TYR A 1 87  ? 76.265  74.367 92.470  1.00 0.64 ? 87  TYR A C   1 
ATOM 657  O O   . TYR A 1 87  ? 75.649  74.630 93.506  1.00 0.64 ? 87  TYR A O   1 
ATOM 658  C CB  . TYR A 1 87  ? 75.393  72.248 91.504  1.00 0.64 ? 87  TYR A CB  1 
ATOM 659  C CG  . TYR A 1 87  ? 75.660  70.863 90.979  1.00 0.64 ? 87  TYR A CG  1 
ATOM 660  C CD1 . TYR A 1 87  ? 75.989  70.654 89.628  1.00 0.64 ? 87  TYR A CD1 1 
ATOM 661  C CD2 . TYR A 1 87  ? 75.437  69.745 91.801  1.00 0.64 ? 87  TYR A CD2 1 
ATOM 662  C CE1 . TYR A 1 87  ? 76.075  69.351 89.110  1.00 0.64 ? 87  TYR A CE1 1 
ATOM 663  C CE2 . TYR A 1 87  ? 75.535  68.448 91.289  1.00 0.64 ? 87  TYR A CE2 1 
ATOM 664  C CZ  . TYR A 1 87  ? 75.847  68.256 89.945  1.00 0.64 ? 87  TYR A CZ  1 
ATOM 665  O OH  . TYR A 1 87  ? 75.890  66.954 89.433  1.00 0.64 ? 87  TYR A OH  1 
ATOM 666  N N   . ARG A 1 88  ? 76.611  75.324 91.588  1.00 0.61 ? 88  ARG A N   1 
ATOM 667  C CA  . ARG A 1 88  ? 76.303  76.733 91.719  1.00 0.61 ? 88  ARG A CA  1 
ATOM 668  C C   . ARG A 1 88  ? 75.554  77.190 90.484  1.00 0.61 ? 88  ARG A C   1 
ATOM 669  O O   . ARG A 1 88  ? 76.057  77.093 89.367  1.00 0.61 ? 88  ARG A O   1 
ATOM 670  C CB  . ARG A 1 88  ? 77.625  77.556 91.827  1.00 0.61 ? 88  ARG A CB  1 
ATOM 671  C CG  . ARG A 1 88  ? 77.506  79.092 91.665  1.00 0.61 ? 88  ARG A CG  1 
ATOM 672  C CD  . ARG A 1 88  ? 78.850  79.852 91.675  1.00 0.61 ? 88  ARG A CD  1 
ATOM 673  N NE  . ARG A 1 88  ? 79.182  80.226 93.088  1.00 0.61 ? 88  ARG A NE  1 
ATOM 674  C CZ  . ARG A 1 88  ? 80.367  80.731 93.468  1.00 0.61 ? 88  ARG A CZ  1 
ATOM 675  N NH1 . ARG A 1 88  ? 80.486  81.314 94.657  1.00 0.61 ? 88  ARG A NH1 1 
ATOM 676  N NH2 . ARG A 1 88  ? 81.445  80.669 92.700  1.00 0.61 ? 88  ARG A NH2 1 
ATOM 677  N N   . ARG A 1 89  ? 74.336  77.741 90.653  1.00 0.57 ? 89  ARG A N   1 
ATOM 678  C CA  . ARG A 1 89  ? 73.640  78.460 89.596  1.00 0.57 ? 89  ARG A CA  1 
ATOM 679  C C   . ARG A 1 89  ? 74.255  79.844 89.463  1.00 0.57 ? 89  ARG A C   1 
ATOM 680  O O   . ARG A 1 89  ? 74.262  80.600 90.431  1.00 0.57 ? 89  ARG A O   1 
ATOM 681  C CB  . ARG A 1 89  ? 72.137  78.608 89.939  1.00 0.57 ? 89  ARG A CB  1 
ATOM 682  C CG  . ARG A 1 89  ? 71.270  79.285 88.855  1.00 0.57 ? 89  ARG A CG  1 
ATOM 683  C CD  . ARG A 1 89  ? 69.775  79.223 89.203  1.00 0.57 ? 89  ARG A CD  1 
ATOM 684  N NE  . ARG A 1 89  ? 69.007  79.893 88.102  1.00 0.57 ? 89  ARG A NE  1 
ATOM 685  C CZ  . ARG A 1 89  ? 67.671  79.860 87.995  1.00 0.57 ? 89  ARG A CZ  1 
ATOM 686  N NH1 . ARG A 1 89  ? 67.067  80.514 87.005  1.00 0.57 ? 89  ARG A NH1 1 
ATOM 687  N NH2 . ARG A 1 89  ? 66.926  79.182 88.862  1.00 0.57 ? 89  ARG A NH2 1 
ATOM 688  N N   . ALA A 1 90  ? 74.806  80.203 88.288  1.00 0.54 ? 90  ALA A N   1 
ATOM 689  C CA  . ALA A 1 90  ? 75.606  81.401 88.136  1.00 0.54 ? 90  ALA A CA  1 
ATOM 690  C C   . ALA A 1 90  ? 74.828  82.526 87.457  1.00 0.54 ? 90  ALA A C   1 
ATOM 691  O O   . ALA A 1 90  ? 74.171  82.333 86.436  1.00 0.54 ? 90  ALA A O   1 
ATOM 692  C CB  . ALA A 1 90  ? 76.862  81.046 87.306  1.00 0.54 ? 90  ALA A CB  1 
ATOM 693  N N   . THR A 1 91  ? 74.912  83.771 87.979  1.00 0.39 ? 91  THR A N   1 
ATOM 694  C CA  . THR A 1 91  ? 74.162  84.916 87.453  1.00 0.39 ? 91  THR A CA  1 
ATOM 695  C C   . THR A 1 91  ? 74.932  85.629 86.364  1.00 0.39 ? 91  THR A C   1 
ATOM 696  O O   . THR A 1 91  ? 74.490  86.617 85.784  1.00 0.39 ? 91  THR A O   1 
ATOM 697  C CB  . THR A 1 91  ? 73.810  85.984 88.497  1.00 0.39 ? 91  THR A CB  1 
ATOM 698  O OG1 . THR A 1 91  ? 74.940  86.608 89.093  1.00 0.39 ? 91  THR A OG1 1 
ATOM 699  C CG2 . THR A 1 91  ? 72.979  85.342 89.618  1.00 0.39 ? 91  THR A CG2 1 
ATOM 700  N N   . ARG A 1 92  ? 76.135  85.121 86.039  1.00 0.32 ? 92  ARG A N   1 
ATOM 701  C CA  . ARG A 1 92  ? 77.075  85.785 85.168  1.00 0.32 ? 92  ARG A CA  1 
ATOM 702  C C   . ARG A 1 92  ? 76.665  85.997 83.717  1.00 0.32 ? 92  ARG A C   1 
ATOM 703  O O   . ARG A 1 92  ? 76.927  87.075 83.171  1.00 0.32 ? 92  ARG A O   1 
ATOM 704  C CB  . ARG A 1 92  ? 78.424  85.027 85.171  1.00 0.32 ? 92  ARG A CB  1 
ATOM 705  C CG  . ARG A 1 92  ? 79.583  85.628 84.331  1.00 0.32 ? 92  ARG A CG  1 
ATOM 706  C CD  . ARG A 1 92  ? 80.139  86.977 84.824  1.00 0.32 ? 92  ARG A CD  1 
ATOM 707  N NE  . ARG A 1 92  ? 79.243  88.070 84.328  1.00 0.32 ? 92  ARG A NE  1 
ATOM 708  C CZ  . ARG A 1 92  ? 79.377  89.366 84.643  1.00 0.32 ? 92  ARG A CZ  1 
ATOM 709  N NH1 . ARG A 1 92  ? 78.484  90.242 84.192  1.00 0.32 ? 92  ARG A NH1 1 
ATOM 710  N NH2 . ARG A 1 92  ? 80.376  89.787 85.411  1.00 0.32 ? 92  ARG A NH2 1 
ATOM 711  N N   . ARG A 1 93  ? 76.086  84.982 83.035  1.00 0.41 ? 93  ARG A N   1 
ATOM 712  C CA  . ARG A 1 93  ? 75.737  85.122 81.635  1.00 0.41 ? 93  ARG A CA  1 
ATOM 713  C C   . ARG A 1 93  ? 74.805  84.041 81.109  1.00 0.41 ? 93  ARG A C   1 
ATOM 714  O O   . ARG A 1 93  ? 74.824  82.898 81.572  1.00 0.41 ? 93  ARG A O   1 
ATOM 715  C CB  . ARG A 1 93  ? 76.991  85.116 80.708  1.00 0.41 ? 93  ARG A CB  1 
ATOM 716  C CG  . ARG A 1 93  ? 77.829  83.817 80.743  1.00 0.41 ? 93  ARG A CG  1 
ATOM 717  C CD  . ARG A 1 93  ? 78.998  83.776 79.746  1.00 0.41 ? 93  ARG A CD  1 
ATOM 718  N NE  . ARG A 1 93  ? 80.079  84.715 80.212  1.00 0.41 ? 93  ARG A NE  1 
ATOM 719  C CZ  . ARG A 1 93  ? 80.361  85.915 79.678  1.00 0.41 ? 93  ARG A CZ  1 
ATOM 720  N NH1 . ARG A 1 93  ? 81.379  86.623 80.167  1.00 0.41 ? 93  ARG A NH1 1 
ATOM 721  N NH2 . ARG A 1 93  ? 79.660  86.424 78.672  1.00 0.41 ? 93  ARG A NH2 1 
ATOM 722  N N   . ILE A 1 94  ? 74.049  84.382 80.044  1.00 0.42 ? 94  ILE A N   1 
ATOM 723  C CA  . ILE A 1 94  ? 73.409  83.453 79.121  1.00 0.42 ? 94  ILE A CA  1 
ATOM 724  C C   . ILE A 1 94  ? 74.253  83.522 77.855  1.00 0.42 ? 94  ILE A C   1 
ATOM 725  O O   . ILE A 1 94  ? 74.696  84.600 77.461  1.00 0.42 ? 94  ILE A O   1 
ATOM 726  C CB  . ILE A 1 94  ? 71.950  83.823 78.816  1.00 0.42 ? 94  ILE A CB  1 
ATOM 727  C CG1 . ILE A 1 94  ? 71.091  83.738 80.100  1.00 0.42 ? 94  ILE A CG1 1 
ATOM 728  C CG2 . ILE A 1 94  ? 71.361  82.895 77.723  1.00 0.42 ? 94  ILE A CG2 1 
ATOM 729  C CD1 . ILE A 1 94  ? 69.706  84.388 79.982  1.00 0.42 ? 94  ILE A CD1 1 
ATOM 730  N N   . ARG A 1 95  ? 74.571  82.374 77.215  1.00 0.39 ? 95  ARG A N   1 
ATOM 731  C CA  . ARG A 1 95  ? 75.334  82.347 75.978  1.00 0.39 ? 95  ARG A CA  1 
ATOM 732  C C   . ARG A 1 95  ? 74.629  81.458 74.967  1.00 0.39 ? 95  ARG A C   1 
ATOM 733  O O   . ARG A 1 95  ? 74.120  80.396 75.319  1.00 0.39 ? 95  ARG A O   1 
ATOM 734  C CB  . ARG A 1 95  ? 76.783  81.839 76.220  1.00 0.39 ? 95  ARG A CB  1 
ATOM 735  C CG  . ARG A 1 95  ? 77.717  81.876 74.988  1.00 0.39 ? 95  ARG A CG  1 
ATOM 736  C CD  . ARG A 1 95  ? 79.175  81.532 75.325  1.00 0.39 ? 95  ARG A CD  1 
ATOM 737  N NE  . ARG A 1 95  ? 79.963  81.566 74.048  1.00 0.39 ? 95  ARG A NE  1 
ATOM 738  C CZ  . ARG A 1 95  ? 81.281  81.331 73.958  1.00 0.39 ? 95  ARG A CZ  1 
ATOM 739  N NH1 . ARG A 1 95  ? 81.888  81.377 72.775  1.00 0.39 ? 95  ARG A NH1 1 
ATOM 740  N NH2 . ARG A 1 95  ? 82.009  81.079 75.041  1.00 0.39 ? 95  ARG A NH2 1 
ATOM 741  N N   . GLY A 1 96  ? 74.598  81.875 73.678  1.00 0.45 ? 96  GLY A N   1 
ATOM 742  C CA  . GLY A 1 96  ? 73.783  81.245 72.641  1.00 0.45 ? 96  GLY A CA  1 
ATOM 743  C C   . GLY A 1 96  ? 72.300  81.488 72.792  1.00 0.45 ? 96  GLY A C   1 
ATOM 744  O O   . GLY A 1 96  ? 71.878  82.311 73.598  1.00 0.45 ? 96  GLY A O   1 
ATOM 745  N N   . GLY A 1 97  ? 71.472  80.812 71.972  1.00 0.44 ? 97  GLY A N   1 
ATOM 746  C CA  . GLY A 1 97  ? 70.020  80.947 72.031  1.00 0.44 ? 97  GLY A CA  1 
ATOM 747  C C   . GLY A 1 97  ? 69.302  79.653 71.763  1.00 0.44 ? 97  GLY A C   1 
ATOM 748  O O   . GLY A 1 97  ? 69.830  78.774 71.091  1.00 0.44 ? 97  GLY A O   1 
ATOM 749  N N   . ASP A 1 98  ? 68.064  79.508 72.275  1.00 0.39 ? 98  ASP A N   1 
ATOM 750  C CA  . ASP A 1 98  ? 67.251  78.338 72.057  1.00 0.39 ? 98  ASP A CA  1 
ATOM 751  C C   . ASP A 1 98  ? 65.801  78.798 72.100  1.00 0.39 ? 98  ASP A C   1 
ATOM 752  O O   . ASP A 1 98  ? 65.492  79.786 72.768  1.00 0.39 ? 98  ASP A O   1 
ATOM 753  C CB  . ASP A 1 98  ? 67.533  77.264 73.138  1.00 0.39 ? 98  ASP A CB  1 
ATOM 754  C CG  . ASP A 1 98  ? 66.838  75.957 72.793  1.00 0.39 ? 98  ASP A CG  1 
ATOM 755  O OD1 . ASP A 1 98  ? 66.609  75.714 71.573  1.00 0.39 ? 98  ASP A OD1 1 
ATOM 756  O OD2 . ASP A 1 98  ? 66.555  75.162 73.713  1.00 0.39 ? 98  ASP A OD2 1 
ATOM 757  N N   . GLY A 1 99  ? 64.896  78.100 71.371  1.00 0.41 ? 99  GLY A N   1 
ATOM 758  C CA  . GLY A 1 99  ? 63.454  78.362 71.317  1.00 0.41 ? 99  GLY A CA  1 
ATOM 759  C C   . GLY A 1 99  ? 63.015  79.803 71.211  1.00 0.41 ? 99  GLY A C   1 
ATOM 760  O O   . GLY A 1 99  ? 63.502  80.602 70.414  1.00 0.41 ? 99  GLY A O   1 
ATOM 761  N N   . LYS A 1 100 ? 62.026  80.194 72.038  1.00 0.35 ? 100 LYS A N   1 
ATOM 762  C CA  . LYS A 1 100 ? 61.848  81.594 72.370  1.00 0.35 ? 100 LYS A CA  1 
ATOM 763  C C   . LYS A 1 100 ? 62.971  82.040 73.295  1.00 0.35 ? 100 LYS A C   1 
ATOM 764  O O   . LYS A 1 100 ? 63.197  81.422 74.328  1.00 0.35 ? 100 LYS A O   1 
ATOM 765  C CB  . LYS A 1 100 ? 60.494  81.838 73.073  1.00 0.35 ? 100 LYS A CB  1 
ATOM 766  C CG  . LYS A 1 100 ? 59.290  81.571 72.160  1.00 0.35 ? 100 LYS A CG  1 
ATOM 767  C CD  . LYS A 1 100 ? 57.957  81.839 72.880  1.00 0.35 ? 100 LYS A CD  1 
ATOM 768  C CE  . LYS A 1 100 ? 56.714  81.681 71.997  1.00 0.35 ? 100 LYS A CE  1 
ATOM 769  N NZ  . LYS A 1 100 ? 56.515  80.260 71.642  1.00 0.35 ? 100 LYS A NZ  1 
ATOM 770  N N   . MET A 1 101 ? 63.681  83.139 72.958  1.00 0.30 ? 101 MET A N   1 
ATOM 771  C CA  . MET A 1 101 ? 65.005  83.464 73.485  1.00 0.30 ? 101 MET A CA  1 
ATOM 772  C C   . MET A 1 101 ? 65.140  83.545 75.003  1.00 0.30 ? 101 MET A C   1 
ATOM 773  O O   . MET A 1 101 ? 66.169  83.212 75.581  1.00 0.30 ? 101 MET A O   1 
ATOM 774  C CB  . MET A 1 101 ? 65.491  84.788 72.833  1.00 0.30 ? 101 MET A CB  1 
ATOM 775  C CG  . MET A 1 101 ? 66.976  85.137 73.069  1.00 0.30 ? 101 MET A CG  1 
ATOM 776  S SD  . MET A 1 101 ? 68.117  83.928 72.339  1.00 0.30 ? 101 MET A SD  1 
ATOM 777  C CE  . MET A 1 101 ? 69.630  84.805 72.818  1.00 0.30 ? 101 MET A CE  1 
ATOM 778  N N   . LYS A 1 102 ? 64.065  83.971 75.688  1.00 0.42 ? 102 LYS A N   1 
ATOM 779  C CA  . LYS A 1 102 ? 63.979  84.069 77.130  1.00 0.42 ? 102 LYS A CA  1 
ATOM 780  C C   . LYS A 1 102 ? 64.013  82.728 77.880  1.00 0.42 ? 102 LYS A C   1 
ATOM 781  O O   . LYS A 1 102 ? 64.323  82.696 79.068  1.00 0.42 ? 102 LYS A O   1 
ATOM 782  C CB  . LYS A 1 102 ? 62.663  84.823 77.458  1.00 0.42 ? 102 LYS A CB  1 
ATOM 783  C CG  . LYS A 1 102 ? 62.531  85.274 78.922  1.00 0.42 ? 102 LYS A CG  1 
ATOM 784  C CD  . LYS A 1 102 ? 61.285  86.139 79.171  1.00 0.42 ? 102 LYS A CD  1 
ATOM 785  C CE  . LYS A 1 102 ? 61.172  86.589 80.631  1.00 0.42 ? 102 LYS A CE  1 
ATOM 786  N NZ  . LYS A 1 102 ? 59.967  87.427 80.830  1.00 0.42 ? 102 LYS A NZ  1 
ATOM 787  N N   . ASP A 1 103 ? 63.688  81.596 77.210  1.00 0.34 ? 103 ASP A N   1 
ATOM 788  C CA  . ASP A 1 103 ? 63.586  80.279 77.814  1.00 0.34 ? 103 ASP A CA  1 
ATOM 789  C C   . ASP A 1 103 ? 64.962  79.639 78.045  1.00 0.34 ? 103 ASP A C   1 
ATOM 790  O O   . ASP A 1 103 ? 65.152  78.762 78.888  1.00 0.34 ? 103 ASP A O   1 
ATOM 791  C CB  . ASP A 1 103 ? 62.680  79.439 76.872  1.00 0.34 ? 103 ASP A CB  1 
ATOM 792  C CG  . ASP A 1 103 ? 62.015  78.253 77.556  1.00 0.34 ? 103 ASP A CG  1 
ATOM 793  O OD1 . ASP A 1 103 ? 61.665  78.379 78.758  1.00 0.34 ? 103 ASP A OD1 1 
ATOM 794  O OD2 . ASP A 1 103 ? 61.749  77.256 76.836  1.00 0.34 ? 103 ASP A OD2 1 
ATOM 795  N N   . LEU A 1 104 ? 66.013  80.111 77.337  1.00 0.46 ? 104 LEU A N   1 
ATOM 796  C CA  . LEU A 1 104 ? 67.351  79.600 77.569  1.00 0.46 ? 104 LEU A CA  1 
ATOM 797  C C   . LEU A 1 104 ? 67.957  80.107 78.873  1.00 0.46 ? 104 LEU A C   1 
ATOM 798  O O   . LEU A 1 104 ? 68.253  81.286 79.062  1.00 0.46 ? 104 LEU A O   1 
ATOM 799  C CB  . LEU A 1 104 ? 68.312  79.868 76.389  1.00 0.46 ? 104 LEU A CB  1 
ATOM 800  C CG  . LEU A 1 104 ? 69.723  79.243 76.537  1.00 0.46 ? 104 LEU A CG  1 
ATOM 801  C CD1 . LEU A 1 104 ? 69.698  77.714 76.711  1.00 0.46 ? 104 LEU A CD1 1 
ATOM 802  C CD2 . LEU A 1 104 ? 70.591  79.610 75.330  1.00 0.46 ? 104 LEU A CD2 1 
ATOM 803  N N   . SER A 1 105 ? 68.146  79.178 79.828  1.00 0.55 ? 105 SER A N   1 
ATOM 804  C CA  . SER A 1 105 ? 68.719  79.408 81.143  1.00 0.55 ? 105 SER A CA  1 
ATOM 805  C C   . SER A 1 105 ? 70.158  79.922 81.170  1.00 0.55 ? 105 SER A C   1 
ATOM 806  O O   . SER A 1 105 ? 70.934  79.592 80.272  1.00 0.55 ? 105 SER A O   1 
ATOM 807  C CB  . SER A 1 105 ? 68.690  78.123 82.014  1.00 0.55 ? 105 SER A CB  1 
ATOM 808  O OG  . SER A 1 105 ? 67.516  77.349 81.779  1.00 0.55 ? 105 SER A OG  1 
ATOM 809  N N   . PRO A 1 106 ? 70.608  80.702 82.164  1.00 0.55 ? 106 PRO A N   1 
ATOM 810  C CA  . PRO A 1 106 ? 72.030  80.977 82.361  1.00 0.55 ? 106 PRO A CA  1 
ATOM 811  C C   . PRO A 1 106 ? 72.854  79.744 82.700  1.00 0.55 ? 106 PRO A C   1 
ATOM 812  O O   . PRO A 1 106 ? 72.314  78.649 82.848  1.00 0.55 ? 106 PRO A O   1 
ATOM 813  C CB  . PRO A 1 106 ? 72.045  82.006 83.499  1.00 0.55 ? 106 PRO A CB  1 
ATOM 814  C CG  . PRO A 1 106 ? 70.825  81.637 84.340  1.00 0.55 ? 106 PRO A CG  1 
ATOM 815  C CD  . PRO A 1 106 ? 69.805  81.212 83.281  1.00 0.55 ? 106 PRO A CD  1 
ATOM 816  N N   . ARG A 1 107 ? 74.182  79.915 82.798  1.00 0.55 ? 107 ARG A N   1 
ATOM 817  C CA  . ARG A 1 107 ? 75.119  78.867 83.160  1.00 0.55 ? 107 ARG A CA  1 
ATOM 818  C C   . ARG A 1 107 ? 75.084  78.397 84.613  1.00 0.55 ? 107 ARG A C   1 
ATOM 819  O O   . ARG A 1 107 ? 74.741  79.120 85.547  1.00 0.55 ? 107 ARG A O   1 
ATOM 820  C CB  . ARG A 1 107 ? 76.571  79.296 82.854  1.00 0.55 ? 107 ARG A CB  1 
ATOM 821  C CG  . ARG A 1 107 ? 76.929  79.277 81.358  1.00 0.55 ? 107 ARG A CG  1 
ATOM 822  C CD  . ARG A 1 107 ? 78.404  79.612 81.172  1.00 0.55 ? 107 ARG A CD  1 
ATOM 823  N NE  . ARG A 1 107 ? 78.803  79.366 79.754  1.00 0.55 ? 107 ARG A NE  1 
ATOM 824  C CZ  . ARG A 1 107 ? 80.087  79.289 79.380  1.00 0.55 ? 107 ARG A CZ  1 
ATOM 825  N NH1 . ARG A 1 107 ? 80.387  78.887 78.145  1.00 0.55 ? 107 ARG A NH1 1 
ATOM 826  N NH2 . ARG A 1 107 ? 81.078  79.562 80.224  1.00 0.55 ? 107 ARG A NH2 1 
ATOM 827  N N   . TRP A 1 108 ? 75.502  77.138 84.823  1.00 0.52 ? 108 TRP A N   1 
ATOM 828  C CA  . TRP A 1 108 ? 75.785  76.546 86.110  1.00 0.52 ? 108 TRP A CA  1 
ATOM 829  C C   . TRP A 1 108 ? 77.254  76.145 86.150  1.00 0.52 ? 108 TRP A C   1 
ATOM 830  O O   . TRP A 1 108 ? 77.842  75.734 85.149  1.00 0.52 ? 108 TRP A O   1 
ATOM 831  C CB  . TRP A 1 108 ? 74.940  75.269 86.342  1.00 0.52 ? 108 TRP A CB  1 
ATOM 832  C CG  . TRP A 1 108 ? 73.603  75.411 87.038  1.00 0.52 ? 108 TRP A CG  1 
ATOM 833  C CD1 . TRP A 1 108 ? 73.283  74.867 88.247  1.00 0.52 ? 108 TRP A CD1 1 
ATOM 834  C CD2 . TRP A 1 108 ? 72.400  76.038 86.551  1.00 0.52 ? 108 TRP A CD2 1 
ATOM 835  N NE1 . TRP A 1 108 ? 71.965  75.107 88.548  1.00 0.52 ? 108 TRP A NE1 1 
ATOM 836  C CE2 . TRP A 1 108 ? 71.409  75.833 87.531  1.00 0.52 ? 108 TRP A CE2 1 
ATOM 837  C CE3 . TRP A 1 108 ? 72.105  76.732 85.384  1.00 0.52 ? 108 TRP A CE3 1 
ATOM 838  C CZ2 . TRP A 1 108 ? 70.128  76.328 87.366  1.00 0.52 ? 108 TRP A CZ2 1 
ATOM 839  C CZ3 . TRP A 1 108 ? 70.824  77.289 85.248  1.00 0.52 ? 108 TRP A CZ3 1 
ATOM 840  C CH2 . TRP A 1 108 ? 69.847  77.095 86.227  1.00 0.52 ? 108 TRP A CH2 1 
ATOM 841  N N   . TYR A 1 109 ? 77.870  76.248 87.344  1.00 0.62 ? 109 TYR A N   1 
ATOM 842  C CA  . TYR A 1 109 ? 79.275  75.974 87.601  1.00 0.62 ? 109 TYR A CA  1 
ATOM 843  C C   . TYR A 1 109 ? 79.384  75.214 88.924  1.00 0.62 ? 109 TYR A C   1 
ATOM 844  O O   . TYR A 1 109 ? 78.375  74.866 89.532  1.00 0.62 ? 109 TYR A O   1 
ATOM 845  C CB  . TYR A 1 109 ? 80.114  77.280 87.724  1.00 0.62 ? 109 TYR A CB  1 
ATOM 846  C CG  . TYR A 1 109 ? 80.189  78.100 86.461  1.00 0.62 ? 109 TYR A CG  1 
ATOM 847  C CD1 . TYR A 1 109 ? 80.489  77.532 85.212  1.00 0.62 ? 109 TYR A CD1 1 
ATOM 848  C CD2 . TYR A 1 109 ? 80.068  79.497 86.549  1.00 0.62 ? 109 TYR A CD2 1 
ATOM 849  C CE1 . TYR A 1 109 ? 80.644  78.340 84.074  1.00 0.62 ? 109 TYR A CE1 1 
ATOM 850  C CE2 . TYR A 1 109 ? 80.226  80.305 85.417  1.00 0.62 ? 109 TYR A CE2 1 
ATOM 851  C CZ  . TYR A 1 109 ? 80.511  79.728 84.178  1.00 0.62 ? 109 TYR A CZ  1 
ATOM 852  O OH  . TYR A 1 109 ? 80.703  80.572 83.063  1.00 0.62 ? 109 TYR A OH  1 
ATOM 853  N N   . PHE A 1 110 ? 80.614  74.928 89.410  1.00 0.62 ? 110 PHE A N   1 
ATOM 854  C CA  . PHE A 1 110 ? 80.852  74.275 90.694  1.00 0.62 ? 110 PHE A CA  1 
ATOM 855  C C   . PHE A 1 110 ? 81.594  75.223 91.636  1.00 0.62 ? 110 PHE A C   1 
ATOM 856  O O   . PHE A 1 110 ? 82.388  76.053 91.201  1.00 0.62 ? 110 PHE A O   1 
ATOM 857  C CB  . PHE A 1 110 ? 81.676  72.965 90.559  1.00 0.62 ? 110 PHE A CB  1 
ATOM 858  C CG  . PHE A 1 110 ? 80.862  71.874 89.924  1.00 0.62 ? 110 PHE A CG  1 
ATOM 859  C CD1 . PHE A 1 110 ? 80.085  71.018 90.721  1.00 0.62 ? 110 PHE A CD1 1 
ATOM 860  C CD2 . PHE A 1 110 ? 80.883  71.669 88.535  1.00 0.62 ? 110 PHE A CD2 1 
ATOM 861  C CE1 . PHE A 1 110 ? 79.363  69.967 90.146  1.00 0.62 ? 110 PHE A CE1 1 
ATOM 862  C CE2 . PHE A 1 110 ? 80.157  70.622 87.954  1.00 0.62 ? 110 PHE A CE2 1 
ATOM 863  C CZ  . PHE A 1 110 ? 79.404  69.763 88.763  1.00 0.62 ? 110 PHE A CZ  1 
ATOM 864  N N   . TYR A 1 111 ? 81.324  75.123 92.955  1.00 0.58 ? 111 TYR A N   1 
ATOM 865  C CA  . TYR A 1 111 ? 81.919  75.950 93.994  1.00 0.58 ? 111 TYR A CA  1 
ATOM 866  C C   . TYR A 1 111 ? 82.253  75.061 95.193  1.00 0.58 ? 111 TYR A C   1 
ATOM 867  O O   . TYR A 1 111 ? 81.478  74.176 95.548  1.00 0.58 ? 111 TYR A O   1 
ATOM 868  C CB  . TYR A 1 111 ? 80.927  77.089 94.388  1.00 0.58 ? 111 TYR A CB  1 
ATOM 869  C CG  . TYR A 1 111 ? 81.245  77.804 95.684  1.00 0.58 ? 111 TYR A CG  1 
ATOM 870  C CD1 . TYR A 1 111 ? 82.210  78.821 95.764  1.00 0.58 ? 111 TYR A CD1 1 
ATOM 871  C CD2 . TYR A 1 111 ? 80.582  77.411 96.857  1.00 0.58 ? 111 TYR A CD2 1 
ATOM 872  C CE1 . TYR A 1 111 ? 82.497  79.434 96.994  1.00 0.58 ? 111 TYR A CE1 1 
ATOM 873  C CE2 . TYR A 1 111 ? 80.875  78.015 98.082  1.00 0.58 ? 111 TYR A CE2 1 
ATOM 874  C CZ  . TYR A 1 111 ? 81.850  79.002 98.157  1.00 0.58 ? 111 TYR A CZ  1 
ATOM 875  O OH  . TYR A 1 111 ? 82.158  79.520 99.424  1.00 0.58 ? 111 TYR A OH  1 
ATOM 876  N N   . TYR A 1 112 ? 83.418  75.286 95.840  1.00 0.60 ? 112 TYR A N   1 
ATOM 877  C CA  . TYR A 1 112 ? 83.899  74.527 96.985  1.00 0.60 ? 112 TYR A CA  1 
ATOM 878  C C   . TYR A 1 112 ? 83.694  75.359 98.236  1.00 0.60 ? 112 TYR A C   1 
ATOM 879  O O   . TYR A 1 112 ? 84.104  76.513 98.300  1.00 0.60 ? 112 TYR A O   1 
ATOM 880  C CB  . TYR A 1 112 ? 85.403  74.148 96.837  1.00 0.60 ? 112 TYR A CB  1 
ATOM 881  C CG  . TYR A 1 112 ? 85.547  72.906 95.996  1.00 0.60 ? 112 TYR A CG  1 
ATOM 882  C CD1 . TYR A 1 112 ? 85.212  72.890 94.631  1.00 0.60 ? 112 TYR A CD1 1 
ATOM 883  C CD2 . TYR A 1 112 ? 85.972  71.710 96.596  1.00 0.60 ? 112 TYR A CD2 1 
ATOM 884  C CE1 . TYR A 1 112 ? 85.253  71.696 93.898  1.00 0.60 ? 112 TYR A CE1 1 
ATOM 885  C CE2 . TYR A 1 112 ? 86.004  70.513 95.870  1.00 0.60 ? 112 TYR A CE2 1 
ATOM 886  C CZ  . TYR A 1 112 ? 85.644  70.506 94.519  1.00 0.60 ? 112 TYR A CZ  1 
ATOM 887  O OH  . TYR A 1 112 ? 85.619  69.294 93.806  1.00 0.60 ? 112 TYR A OH  1 
ATOM 888  N N   . LEU A 1 113 ? 83.002  74.798 99.252  1.00 0.55 ? 113 LEU A N   1 
ATOM 889  C CA  . LEU A 1 113 ? 82.525  75.547 100.406 1.00 0.55 ? 113 LEU A CA  1 
ATOM 890  C C   . LEU A 1 113 ? 83.550  76.236 101.302 1.00 0.55 ? 113 LEU A C   1 
ATOM 891  O O   . LEU A 1 113 ? 84.638  75.739 101.591 1.00 0.55 ? 113 LEU A O   1 
ATOM 892  C CB  . LEU A 1 113 ? 81.615  74.706 101.337 1.00 0.55 ? 113 LEU A CB  1 
ATOM 893  C CG  . LEU A 1 113 ? 80.381  74.058 100.683 1.00 0.55 ? 113 LEU A CG  1 
ATOM 894  C CD1 . LEU A 1 113 ? 79.549  73.333 101.753 1.00 0.55 ? 113 LEU A CD1 1 
ATOM 895  C CD2 . LEU A 1 113 ? 79.494  75.049 99.911  1.00 0.55 ? 113 LEU A CD2 1 
ATOM 896  N N   . GLY A 1 114 ? 83.153  77.405 101.852 1.00 0.51 ? 114 GLY A N   1 
ATOM 897  C CA  . GLY A 1 114 ? 83.970  78.151 102.794 1.00 0.51 ? 114 GLY A CA  1 
ATOM 898  C C   . GLY A 1 114 ? 84.934  79.149 102.229 1.00 0.51 ? 114 GLY A C   1 
ATOM 899  O O   . GLY A 1 114 ? 85.805  79.606 102.965 1.00 0.51 ? 114 GLY A O   1 
ATOM 900  N N   . THR A 1 115 ? 84.849  79.510 100.939 1.00 0.39 ? 115 THR A N   1 
ATOM 901  C CA  . THR A 1 115 ? 85.745  80.472 100.318 1.00 0.39 ? 115 THR A CA  1 
ATOM 902  C C   . THR A 1 115 ? 85.011  81.786 100.058 1.00 0.39 ? 115 THR A C   1 
ATOM 903  O O   . THR A 1 115 ? 83.869  81.829 99.617  1.00 0.39 ? 115 THR A O   1 
ATOM 904  C CB  . THR A 1 115 ? 86.413  79.925 99.049  1.00 0.39 ? 115 THR A CB  1 
ATOM 905  O OG1 . THR A 1 115 ? 85.481  79.514 98.069  1.00 0.39 ? 115 THR A OG1 1 
ATOM 906  C CG2 . THR A 1 115 ? 87.212  78.650 99.358  1.00 0.39 ? 115 THR A CG2 1 
ATOM 907  N N   . GLY A 1 116 ? 85.609  82.951 100.401 1.00 0.37 ? 116 GLY A N   1 
ATOM 908  C CA  . GLY A 1 116 ? 84.862  84.190 100.231 1.00 0.37 ? 116 GLY A CA  1 
ATOM 909  C C   . GLY A 1 116 ? 85.599  85.362 100.821 1.00 0.37 ? 116 GLY A C   1 
ATOM 910  O O   . GLY A 1 116 ? 86.823  85.306 100.920 1.00 0.37 ? 116 GLY A O   1 
ATOM 911  N N   . PRO A 1 117 ? 84.923  86.444 101.216 1.00 0.27 ? 117 PRO A N   1 
ATOM 912  C CA  . PRO A 1 117 ? 85.504  87.547 101.988 1.00 0.27 ? 117 PRO A CA  1 
ATOM 913  C C   . PRO A 1 117 ? 86.164  87.184 103.317 1.00 0.27 ? 117 PRO A C   1 
ATOM 914  O O   . PRO A 1 117 ? 85.999  86.066 103.798 1.00 0.27 ? 117 PRO A O   1 
ATOM 915  C CB  . PRO A 1 117 ? 84.315  88.499 102.235 1.00 0.27 ? 117 PRO A CB  1 
ATOM 916  C CG  . PRO A 1 117 ? 83.294  88.147 101.153 1.00 0.27 ? 117 PRO A CG  1 
ATOM 917  C CD  . PRO A 1 117 ? 83.494  86.645 100.967 1.00 0.27 ? 117 PRO A CD  1 
ATOM 918  N N   . GLU A 1 118 ? 86.833  88.176 103.962 1.00 0.21 ? 118 GLU A N   1 
ATOM 919  C CA  . GLU A 1 118 ? 87.588  88.100 105.218 1.00 0.21 ? 118 GLU A CA  1 
ATOM 920  C C   . GLU A 1 118 ? 86.826  87.478 106.394 1.00 0.21 ? 118 GLU A C   1 
ATOM 921  O O   . GLU A 1 118 ? 87.388  86.877 107.305 1.00 0.21 ? 118 GLU A O   1 
ATOM 922  C CB  . GLU A 1 118 ? 88.060  89.538 105.592 1.00 0.21 ? 118 GLU A CB  1 
ATOM 923  C CG  . GLU A 1 118 ? 89.052  89.644 106.789 1.00 0.21 ? 118 GLU A CG  1 
ATOM 924  C CD  . GLU A 1 118 ? 90.424  89.014 106.536 1.00 0.21 ? 118 GLU A CD  1 
ATOM 925  O OE1 . GLU A 1 118 ? 90.774  88.790 105.350 1.00 0.21 ? 118 GLU A OE1 1 
ATOM 926  O OE2 . GLU A 1 118 ? 91.138  88.744 107.544 1.00 0.21 ? 118 GLU A OE2 1 
ATOM 927  N N   . ALA A 1 119 ? 85.482  87.571 106.372 1.00 0.24 ? 119 ALA A N   1 
ATOM 928  C CA  . ALA A 1 119 ? 84.597  86.948 107.332 1.00 0.24 ? 119 ALA A CA  1 
ATOM 929  C C   . ALA A 1 119 ? 84.544  85.413 107.257 1.00 0.24 ? 119 ALA A C   1 
ATOM 930  O O   . ALA A 1 119 ? 84.028  84.772 108.170 1.00 0.24 ? 119 ALA A O   1 
ATOM 931  C CB  . ALA A 1 119 ? 83.176  87.518 107.126 1.00 0.24 ? 119 ALA A CB  1 
ATOM 932  N N   . GLY A 1 120 ? 85.060  84.778 106.175 1.00 0.33 ? 120 GLY A N   1 
ATOM 933  C CA  . GLY A 1 120 ? 85.161  83.318 106.089 1.00 0.33 ? 120 GLY A CA  1 
ATOM 934  C C   . GLY A 1 120 ? 83.860  82.601 105.838 1.00 0.33 ? 120 GLY A C   1 
ATOM 935  O O   . GLY A 1 120 ? 83.591  81.533 106.385 1.00 0.33 ? 120 GLY A O   1 
ATOM 936  N N   . LEU A 1 121 ? 83.004  83.210 105.000 1.00 0.29 ? 121 LEU A N   1 
ATOM 937  C CA  . LEU A 1 121 ? 81.649  82.778 104.731 1.00 0.29 ? 121 LEU A CA  1 
ATOM 938  C C   . LEU A 1 121 ? 81.517  81.377 104.117 1.00 0.29 ? 121 LEU A C   1 
ATOM 939  O O   . LEU A 1 121 ? 82.381  80.960 103.349 1.00 0.29 ? 121 LEU A O   1 
ATOM 940  C CB  . LEU A 1 121 ? 80.915  83.808 103.835 1.00 0.29 ? 121 LEU A CB  1 
ATOM 941  C CG  . LEU A 1 121 ? 80.849  85.248 104.390 1.00 0.29 ? 121 LEU A CG  1 
ATOM 942  C CD1 . LEU A 1 121 ? 80.140  86.163 103.377 1.00 0.29 ? 121 LEU A CD1 1 
ATOM 943  C CD2 . LEU A 1 121 ? 80.144  85.336 105.755 1.00 0.29 ? 121 LEU A CD2 1 
ATOM 944  N N   . PRO A 1 122 ? 80.473  80.585 104.395 1.00 0.51 ? 122 PRO A N   1 
ATOM 945  C CA  . PRO A 1 122 ? 80.310  79.259 103.807 1.00 0.51 ? 122 PRO A CA  1 
ATOM 946  C C   . PRO A 1 122 ? 80.072  79.326 102.303 1.00 0.51 ? 122 PRO A C   1 
ATOM 947  O O   . PRO A 1 122 ? 80.473  78.412 101.579 1.00 0.51 ? 122 PRO A O   1 
ATOM 948  C CB  . PRO A 1 122 ? 79.149  78.637 104.605 1.00 0.51 ? 122 PRO A CB  1 
ATOM 949  C CG  . PRO A 1 122 ? 78.338  79.837 105.098 1.00 0.51 ? 122 PRO A CG  1 
ATOM 950  C CD  . PRO A 1 122 ? 79.404  80.906 105.339 1.00 0.51 ? 122 PRO A CD  1 
ATOM 951  N N   . TYR A 1 123 ? 79.439  80.402 101.813 1.00 0.24 ? 123 TYR A N   1 
ATOM 952  C CA  . TYR A 1 123 ? 79.208  80.673 100.412 1.00 0.24 ? 123 TYR A CA  1 
ATOM 953  C C   . TYR A 1 123 ? 79.850  82.011 100.069 1.00 0.24 ? 123 TYR A C   1 
ATOM 954  O O   . TYR A 1 123 ? 79.884  82.919 100.896 1.00 0.24 ? 123 TYR A O   1 
ATOM 955  C CB  . TYR A 1 123 ? 77.700  80.597 100.031 1.00 0.24 ? 123 TYR A CB  1 
ATOM 956  C CG  . TYR A 1 123 ? 76.841  81.533 100.840 1.00 0.24 ? 123 TYR A CG  1 
ATOM 957  C CD1 . TYR A 1 123 ? 76.691  82.869 100.440 1.00 0.24 ? 123 TYR A CD1 1 
ATOM 958  C CD2 . TYR A 1 123 ? 76.180  81.096 101.999 1.00 0.24 ? 123 TYR A CD2 1 
ATOM 959  C CE1 . TYR A 1 123 ? 75.915  83.757 101.192 1.00 0.24 ? 123 TYR A CE1 1 
ATOM 960  C CE2 . TYR A 1 123 ? 75.397  81.985 102.752 1.00 0.24 ? 123 TYR A CE2 1 
ATOM 961  C CZ  . TYR A 1 123 ? 75.275  83.319 102.351 1.00 0.24 ? 123 TYR A CZ  1 
ATOM 962  O OH  . TYR A 1 123 ? 74.515  84.235 103.102 1.00 0.24 ? 123 TYR A OH  1 
ATOM 963  N N   . GLY A 1 124 ? 80.404  82.155 98.844  1.00 0.29 ? 124 GLY A N   1 
ATOM 964  C CA  . GLY A 1 124 ? 81.199  83.328 98.474  1.00 0.29 ? 124 GLY A CA  1 
ATOM 965  C C   . GLY A 1 124 ? 80.449  84.612 98.216  1.00 0.29 ? 124 GLY A C   1 
ATOM 966  O O   . GLY A 1 124 ? 80.941  85.707 98.487  1.00 0.29 ? 124 GLY A O   1 
ATOM 967  N N   . ALA A 1 125 ? 79.221  84.522 97.683  1.00 0.43 ? 125 ALA A N   1 
ATOM 968  C CA  . ALA A 1 125 ? 78.401  85.678 97.429  1.00 0.43 ? 125 ALA A CA  1 
ATOM 969  C C   . ALA A 1 125 ? 76.944  85.253 97.404  1.00 0.43 ? 125 ALA A C   1 
ATOM 970  O O   . ALA A 1 125 ? 76.639  84.092 97.154  1.00 0.43 ? 125 ALA A O   1 
ATOM 971  C CB  . ALA A 1 125 ? 78.786  86.347 96.088  1.00 0.43 ? 125 ALA A CB  1 
ATOM 972  N N   . ASN A 1 126 ? 76.015  86.196 97.692  1.00 0.36 ? 126 ASN A N   1 
ATOM 973  C CA  . ASN A 1 126 ? 74.578  85.950 97.780  1.00 0.36 ? 126 ASN A CA  1 
ATOM 974  C C   . ASN A 1 126 ? 73.865  85.801 96.432  1.00 0.36 ? 126 ASN A C   1 
ATOM 975  O O   . ASN A 1 126 ? 72.816  85.176 96.335  1.00 0.36 ? 126 ASN A O   1 
ATOM 976  C CB  . ASN A 1 126 ? 73.954  87.133 98.586  1.00 0.36 ? 126 ASN A CB  1 
ATOM 977  C CG  . ASN A 1 126 ? 72.473  86.931 98.918  1.00 0.36 ? 126 ASN A CG  1 
ATOM 978  O OD1 . ASN A 1 126 ? 72.095  85.951 99.553  1.00 0.36 ? 126 ASN A OD1 1 
ATOM 979  N ND2 . ASN A 1 126 ? 71.610  87.893 98.511  1.00 0.36 ? 126 ASN A ND2 1 
ATOM 980  N N   . LYS A 1 127 ? 74.384  86.423 95.355  1.00 0.42 ? 127 LYS A N   1 
ATOM 981  C CA  . LYS A 1 127 ? 73.708  86.425 94.068  1.00 0.42 ? 127 LYS A CA  1 
ATOM 982  C C   . LYS A 1 127 ? 73.686  85.082 93.346  1.00 0.42 ? 127 LYS A C   1 
ATOM 983  O O   . LYS A 1 127 ? 72.645  84.659 92.848  1.00 0.42 ? 127 LYS A O   1 
ATOM 984  C CB  . LYS A 1 127 ? 74.338  87.491 93.141  1.00 0.42 ? 127 LYS A CB  1 
ATOM 985  C CG  . LYS A 1 127 ? 74.102  88.934 93.621  1.00 0.42 ? 127 LYS A CG  1 
ATOM 986  C CD  . LYS A 1 127 ? 74.486  89.985 92.560  1.00 0.42 ? 127 LYS A CD  1 
ATOM 987  C CE  . LYS A 1 127 ? 75.981  90.107 92.238  1.00 0.42 ? 127 LYS A CE  1 
ATOM 988  N NZ  . LYS A 1 127 ? 76.677  90.838 93.319  1.00 0.42 ? 127 LYS A NZ  1 
ATOM 989  N N   . ASP A 1 128 ? 74.836  84.383 93.286  1.00 0.39 ? 128 ASP A N   1 
ATOM 990  C CA  . ASP A 1 128 ? 74.929  83.054 92.724  1.00 0.39 ? 128 ASP A CA  1 
ATOM 991  C C   . ASP A 1 128 ? 74.421  81.997 93.697  1.00 0.39 ? 128 ASP A C   1 
ATOM 992  O O   . ASP A 1 128 ? 74.814  81.934 94.861  1.00 0.39 ? 128 ASP A O   1 
ATOM 993  C CB  . ASP A 1 128 ? 76.384  82.690 92.352  1.00 0.39 ? 128 ASP A CB  1 
ATOM 994  C CG  . ASP A 1 128 ? 76.934  83.546 91.229  1.00 0.39 ? 128 ASP A CG  1 
ATOM 995  O OD1 . ASP A 1 128 ? 76.142  83.987 90.361  1.00 0.39 ? 128 ASP A OD1 1 
ATOM 996  O OD2 . ASP A 1 128 ? 78.178  83.714 91.201  1.00 0.39 ? 128 ASP A OD2 1 
ATOM 997  N N   . GLY A 1 129 ? 73.527  81.108 93.228  1.00 0.55 ? 129 GLY A N   1 
ATOM 998  C CA  . GLY A 1 129 ? 72.828  80.164 94.090  1.00 0.55 ? 129 GLY A CA  1 
ATOM 999  C C   . GLY A 1 129 ? 73.535  78.853 94.288  1.00 0.55 ? 129 GLY A C   1 
ATOM 1000 O O   . GLY A 1 129 ? 73.577  78.021 93.382  1.00 0.55 ? 129 GLY A O   1 
ATOM 1001 N N   . ILE A 1 130 ? 74.087  78.608 95.495  1.00 0.49 ? 130 ILE A N   1 
ATOM 1002 C CA  . ILE A 1 130 ? 74.578  77.296 95.912  1.00 0.49 ? 130 ILE A CA  1 
ATOM 1003 C C   . ILE A 1 130 ? 73.406  76.352 96.161  1.00 0.49 ? 130 ILE A C   1 
ATOM 1004 O O   . ILE A 1 130 ? 72.394  76.743 96.737  1.00 0.49 ? 130 ILE A O   1 
ATOM 1005 C CB  . ILE A 1 130 ? 75.524  77.373 97.116  1.00 0.49 ? 130 ILE A CB  1 
ATOM 1006 C CG1 . ILE A 1 130 ? 76.673  78.387 96.873  1.00 0.49 ? 130 ILE A CG1 1 
ATOM 1007 C CG2 . ILE A 1 130 ? 76.091  75.982 97.489  1.00 0.49 ? 130 ILE A CG2 1 
ATOM 1008 C CD1 . ILE A 1 130 ? 77.484  78.143 95.594  1.00 0.49 ? 130 ILE A CD1 1 
ATOM 1009 N N   . ILE A 1 131 ? 73.490  75.093 95.676  1.00 0.50 ? 131 ILE A N   1 
ATOM 1010 C CA  . ILE A 1 131 ? 72.332  74.200 95.641  1.00 0.50 ? 131 ILE A CA  1 
ATOM 1011 C C   . ILE A 1 131 ? 72.389  73.124 96.728  1.00 0.50 ? 131 ILE A C   1 
ATOM 1012 O O   . ILE A 1 131 ? 71.388  72.493 97.058  1.00 0.50 ? 131 ILE A O   1 
ATOM 1013 C CB  . ILE A 1 131 ? 72.221  73.651 94.215  1.00 0.50 ? 131 ILE A CB  1 
ATOM 1014 C CG1 . ILE A 1 131 ? 71.925  74.845 93.270  1.00 0.50 ? 131 ILE A CG1 1 
ATOM 1015 C CG2 . ILE A 1 131 ? 71.129  72.565 94.071  1.00 0.50 ? 131 ILE A CG2 1 
ATOM 1016 C CD1 . ILE A 1 131 ? 72.059  74.540 91.781  1.00 0.50 ? 131 ILE A CD1 1 
ATOM 1017 N N   . TRP A 1 132 ? 73.562  72.928 97.363  1.00 0.37 ? 132 TRP A N   1 
ATOM 1018 C CA  . TRP A 1 132 ? 73.752  72.148 98.589  1.00 0.37 ? 132 TRP A CA  1 
ATOM 1019 C C   . TRP A 1 132 ? 73.452  70.638 98.516  1.00 0.37 ? 132 TRP A C   1 
ATOM 1020 O O   . TRP A 1 132 ? 73.476  69.936 99.522  1.00 0.37 ? 132 TRP A O   1 
ATOM 1021 C CB  . TRP A 1 132 ? 73.041  72.786 99.818  1.00 0.37 ? 132 TRP A CB  1 
ATOM 1022 C CG  . TRP A 1 132 ? 73.198  74.296 99.982  1.00 0.37 ? 132 TRP A CG  1 
ATOM 1023 C CD1 . TRP A 1 132 ? 72.288  75.251 99.630  1.00 0.37 ? 132 TRP A CD1 1 
ATOM 1024 C CD2 . TRP A 1 132 ? 74.319  75.005 100.552 1.00 0.37 ? 132 TRP A CD2 1 
ATOM 1025 N NE1 . TRP A 1 132 ? 72.770  76.506 99.921  1.00 0.37 ? 132 TRP A NE1 1 
ATOM 1026 C CE2 . TRP A 1 132 ? 74.010  76.382 100.487 1.00 0.37 ? 132 TRP A CE2 1 
ATOM 1027 C CE3 . TRP A 1 132 ? 75.526  74.575 101.094 1.00 0.37 ? 132 TRP A CE3 1 
ATOM 1028 C CZ2 . TRP A 1 132 ? 74.899  77.340 100.948 1.00 0.37 ? 132 TRP A CZ2 1 
ATOM 1029 C CZ3 . TRP A 1 132 ? 76.418  75.548 101.573 1.00 0.37 ? 132 TRP A CZ3 1 
ATOM 1030 C CH2 . TRP A 1 132 ? 76.117  76.914 101.495 1.00 0.37 ? 132 TRP A CH2 1 
ATOM 1031 N N   . VAL A 1 133 ? 73.216  70.068 97.315  1.00 0.39 ? 133 VAL A N   1 
ATOM 1032 C CA  . VAL A 1 133 ? 73.013  68.637 97.122  1.00 0.39 ? 133 VAL A CA  1 
ATOM 1033 C C   . VAL A 1 133 ? 74.318  67.838 97.143  1.00 0.39 ? 133 VAL A C   1 
ATOM 1034 O O   . VAL A 1 133 ? 75.250  68.107 96.386  1.00 0.39 ? 133 VAL A O   1 
ATOM 1035 C CB  . VAL A 1 133 ? 72.199  68.310 95.860  1.00 0.39 ? 133 VAL A CB  1 
ATOM 1036 C CG1 . VAL A 1 133 ? 70.752  68.812 96.045  1.00 0.39 ? 133 VAL A CG1 1 
ATOM 1037 C CG2 . VAL A 1 133 ? 72.820  68.917 94.582  1.00 0.39 ? 133 VAL A CG2 1 
ATOM 1038 N N   . ALA A 1 134 ? 74.416  66.824 98.031  1.00 0.54 ? 134 ALA A N   1 
ATOM 1039 C CA  . ALA A 1 134 ? 75.543  65.919 98.074  1.00 0.54 ? 134 ALA A CA  1 
ATOM 1040 C C   . ALA A 1 134 ? 75.161  64.647 98.821  1.00 0.54 ? 134 ALA A C   1 
ATOM 1041 O O   . ALA A 1 134 ? 74.108  64.560 99.452  1.00 0.54 ? 134 ALA A O   1 
ATOM 1042 C CB  . ALA A 1 134 ? 76.787  66.562 98.728  1.00 0.54 ? 134 ALA A CB  1 
ATOM 1043 N N   . THR A 1 135 ? 76.001  63.597 98.712  1.00 0.52 ? 135 THR A N   1 
ATOM 1044 C CA  . THR A 1 135 ? 75.900  62.347 99.458  1.00 0.52 ? 135 THR A CA  1 
ATOM 1045 C C   . THR A 1 135 ? 76.243  62.512 100.939 1.00 0.52 ? 135 THR A C   1 
ATOM 1046 O O   . THR A 1 135 ? 77.243  63.121 101.296 1.00 0.52 ? 135 THR A O   1 
ATOM 1047 C CB  . THR A 1 135 ? 76.796  61.250 98.867  1.00 0.52 ? 135 THR A CB  1 
ATOM 1048 O OG1 . THR A 1 135 ? 78.128  61.703 98.671  1.00 0.52 ? 135 THR A OG1 1 
ATOM 1049 C CG2 . THR A 1 135 ? 76.296  60.857 97.470  1.00 0.52 ? 135 THR A CG2 1 
ATOM 1050 N N   . GLU A 1 136 ? 75.443  61.904 101.849 1.00 0.48 ? 136 GLU A N   1 
ATOM 1051 C CA  . GLU A 1 136 ? 75.624  61.949 103.307 1.00 0.48 ? 136 GLU A CA  1 
ATOM 1052 C C   . GLU A 1 136 ? 76.931  61.321 103.796 1.00 0.48 ? 136 GLU A C   1 
ATOM 1053 O O   . GLU A 1 136 ? 77.493  61.665 104.833 1.00 0.48 ? 136 GLU A O   1 
ATOM 1054 C CB  . GLU A 1 136 ? 74.419  61.225 103.972 1.00 0.48 ? 136 GLU A CB  1 
ATOM 1055 C CG  . GLU A 1 136 ? 74.390  61.159 105.525 1.00 0.48 ? 136 GLU A CG  1 
ATOM 1056 C CD  . GLU A 1 136 ? 74.063  62.494 106.194 1.00 0.48 ? 136 GLU A CD  1 
ATOM 1057 O OE1 . GLU A 1 136 ? 73.884  63.499 105.458 1.00 0.48 ? 136 GLU A OE1 1 
ATOM 1058 O OE2 . GLU A 1 136 ? 73.894  62.477 107.439 1.00 0.48 ? 136 GLU A OE2 1 
ATOM 1059 N N   . GLY A 1 137 ? 77.474  60.375 103.006 1.00 0.51 ? 137 GLY A N   1 
ATOM 1060 C CA  . GLY A 1 137 ? 78.737  59.705 103.289 1.00 0.51 ? 137 GLY A CA  1 
ATOM 1061 C C   . GLY A 1 137 ? 79.986  60.499 102.995 1.00 0.51 ? 137 GLY A C   1 
ATOM 1062 O O   . GLY A 1 137 ? 81.079  59.973 103.173 1.00 0.51 ? 137 GLY A O   1 
ATOM 1063 N N   . ALA A 1 138 ? 79.881  61.757 102.512 1.00 0.54 ? 138 ALA A N   1 
ATOM 1064 C CA  . ALA A 1 138 ? 81.016  62.650 102.355 1.00 0.54 ? 138 ALA A CA  1 
ATOM 1065 C C   . ALA A 1 138 ? 81.741  62.918 103.675 1.00 0.54 ? 138 ALA A C   1 
ATOM 1066 O O   . ALA A 1 138 ? 81.124  63.112 104.717 1.00 0.54 ? 138 ALA A O   1 
ATOM 1067 C CB  . ALA A 1 138 ? 80.555  63.978 101.718 1.00 0.54 ? 138 ALA A CB  1 
ATOM 1068 N N   . LEU A 1 139 ? 83.084  62.910 103.672 1.00 0.42 ? 139 LEU A N   1 
ATOM 1069 C CA  . LEU A 1 139 ? 83.878  62.848 104.883 1.00 0.42 ? 139 LEU A CA  1 
ATOM 1070 C C   . LEU A 1 139 ? 84.376  64.226 105.286 1.00 0.42 ? 139 LEU A C   1 
ATOM 1071 O O   . LEU A 1 139 ? 84.802  64.451 106.420 1.00 0.42 ? 139 LEU A O   1 
ATOM 1072 C CB  . LEU A 1 139 ? 85.057  61.877 104.618 1.00 0.42 ? 139 LEU A CB  1 
ATOM 1073 C CG  . LEU A 1 139 ? 85.892  61.435 105.839 1.00 0.42 ? 139 LEU A CG  1 
ATOM 1074 C CD1 . LEU A 1 139 ? 85.046  60.692 106.887 1.00 0.42 ? 139 LEU A CD1 1 
ATOM 1075 C CD2 . LEU A 1 139 ? 87.060  60.539 105.390 1.00 0.42 ? 139 LEU A CD2 1 
ATOM 1076 N N   . ASN A 1 140 ? 84.274  65.202 104.363 1.00 0.49 ? 140 ASN A N   1 
ATOM 1077 C CA  . ASN A 1 140 ? 84.519  66.616 104.576 1.00 0.49 ? 140 ASN A CA  1 
ATOM 1078 C C   . ASN A 1 140 ? 85.967  66.944 104.969 1.00 0.49 ? 140 ASN A C   1 
ATOM 1079 O O   . ASN A 1 140 ? 86.213  67.808 105.815 1.00 0.49 ? 140 ASN A O   1 
ATOM 1080 C CB  . ASN A 1 140 ? 83.502  67.235 105.580 1.00 0.49 ? 140 ASN A CB  1 
ATOM 1081 C CG  . ASN A 1 140 ? 82.074  67.035 105.089 1.00 0.49 ? 140 ASN A CG  1 
ATOM 1082 O OD1 . ASN A 1 140 ? 81.694  67.660 104.096 1.00 0.49 ? 140 ASN A OD1 1 
ATOM 1083 N ND2 . ASN A 1 140 ? 81.253  66.223 105.793 1.00 0.49 ? 140 ASN A ND2 1 
ATOM 1084 N N   . THR A 1 141 ? 86.962  66.247 104.369 1.00 0.40 ? 141 THR A N   1 
ATOM 1085 C CA  . THR A 1 141 ? 88.391  66.366 104.681 1.00 0.40 ? 141 THR A CA  1 
ATOM 1086 C C   . THR A 1 141 ? 89.033  67.676 104.230 1.00 0.40 ? 141 THR A C   1 
ATOM 1087 O O   . THR A 1 141 ? 88.672  68.221 103.183 1.00 0.40 ? 141 THR A O   1 
ATOM 1088 C CB  . THR A 1 141 ? 89.277  65.190 104.236 1.00 0.40 ? 141 THR A CB  1 
ATOM 1089 O OG1 . THR A 1 141 ? 89.397  65.041 102.829 1.00 0.40 ? 141 THR A OG1 1 
ATOM 1090 C CG2 . THR A 1 141 ? 88.704  63.883 104.807 1.00 0.40 ? 141 THR A CG2 1 
ATOM 1091 N N   . PRO A 1 142 ? 89.990  68.262 104.948 1.00 0.37 ? 142 PRO A N   1 
ATOM 1092 C CA  . PRO A 1 142 ? 90.691  69.441 104.459 1.00 0.37 ? 142 PRO A CA  1 
ATOM 1093 C C   . PRO A 1 142 ? 91.806  69.080 103.487 1.00 0.37 ? 142 PRO A C   1 
ATOM 1094 O O   . PRO A 1 142 ? 92.581  68.158 103.741 1.00 0.37 ? 142 PRO A O   1 
ATOM 1095 C CB  . PRO A 1 142 ? 91.244  70.088 105.739 1.00 0.37 ? 142 PRO A CB  1 
ATOM 1096 C CG  . PRO A 1 142 ? 91.435  68.922 106.714 1.00 0.37 ? 142 PRO A CG  1 
ATOM 1097 C CD  . PRO A 1 142 ? 90.306  67.960 106.345 1.00 0.37 ? 142 PRO A CD  1 
ATOM 1098 N N   . LYS A 1 143 ? 91.941  69.828 102.370 1.00 0.38 ? 143 LYS A N   1 
ATOM 1099 C CA  . LYS A 1 143 ? 93.050  69.650 101.457 1.00 0.38 ? 143 LYS A CA  1 
ATOM 1100 C C   . LYS A 1 143 ? 93.288  70.954 100.704 1.00 0.38 ? 143 LYS A C   1 
ATOM 1101 O O   . LYS A 1 143 ? 92.362  71.738 100.509 1.00 0.38 ? 143 LYS A O   1 
ATOM 1102 C CB  . LYS A 1 143 ? 92.787  68.477 100.472 1.00 0.38 ? 143 LYS A CB  1 
ATOM 1103 C CG  . LYS A 1 143 ? 94.039  68.015 99.709  1.00 0.38 ? 143 LYS A CG  1 
ATOM 1104 C CD  . LYS A 1 143 ? 93.875  66.661 98.999  1.00 0.38 ? 143 LYS A CD  1 
ATOM 1105 C CE  . LYS A 1 143 ? 95.177  66.223 98.314  1.00 0.38 ? 143 LYS A CE  1 
ATOM 1106 N NZ  . LYS A 1 143 ? 95.058  64.889 97.686  1.00 0.38 ? 143 LYS A NZ  1 
ATOM 1107 N N   . ASP A 1 144 ? 94.546  71.241 100.280 1.00 0.37 ? 144 ASP A N   1 
ATOM 1108 C CA  . ASP A 1 144 ? 94.914  72.434 99.529  1.00 0.37 ? 144 ASP A CA  1 
ATOM 1109 C C   . ASP A 1 144 ? 94.483  72.349 98.061  1.00 0.37 ? 144 ASP A C   1 
ATOM 1110 O O   . ASP A 1 144 ? 93.974  73.294 97.460  1.00 0.37 ? 144 ASP A O   1 
ATOM 1111 C CB  . ASP A 1 144 ? 96.454  72.669 99.620  1.00 0.37 ? 144 ASP A CB  1 
ATOM 1112 C CG  . ASP A 1 144 ? 96.964  72.904 101.029 1.00 0.37 ? 144 ASP A CG  1 
ATOM 1113 O OD1 . ASP A 1 144 ? 96.185  73.160 101.979 1.00 0.37 ? 144 ASP A OD1 1 
ATOM 1114 O OD2 . ASP A 1 144 ? 98.202  72.836 101.244 1.00 0.37 ? 144 ASP A OD2 1 
ATOM 1115 N N   . HIS A 1 145 ? 94.656  71.156 97.457  1.00 0.49 ? 145 HIS A N   1 
ATOM 1116 C CA  . HIS A 1 145 ? 94.636  70.904 96.027  1.00 0.49 ? 145 HIS A CA  1 
ATOM 1117 C C   . HIS A 1 145 ? 93.298  71.037 95.314  1.00 0.49 ? 145 HIS A C   1 
ATOM 1118 O O   . HIS A 1 145 ? 93.258  71.111 94.089  1.00 0.49 ? 145 HIS A O   1 
ATOM 1119 C CB  . HIS A 1 145 ? 95.093  69.443 95.752  1.00 0.49 ? 145 HIS A CB  1 
ATOM 1120 C CG  . HIS A 1 145 ? 96.457  69.069 96.252  1.00 0.49 ? 145 HIS A CG  1 
ATOM 1121 N ND1 . HIS A 1 145 ? 96.756  69.108 97.604  1.00 0.49 ? 145 HIS A ND1 1 
ATOM 1122 C CD2 . HIS A 1 145 ? 97.524  68.610 95.550  1.00 0.49 ? 145 HIS A CD2 1 
ATOM 1123 C CE1 . HIS A 1 145 ? 98.005  68.690 97.687  1.00 0.49 ? 145 HIS A CE1 1 
ATOM 1124 N NE2 . HIS A 1 145 ? 98.515  68.372 96.474  1.00 0.49 ? 145 HIS A NE2 1 
ATOM 1125 N N   . ILE A 1 146 ? 92.173  71.015 96.049  1.00 0.59 ? 146 ILE A N   1 
ATOM 1126 C CA  . ILE A 1 146 ? 90.849  70.855 95.473  1.00 0.59 ? 146 ILE A CA  1 
ATOM 1127 C C   . ILE A 1 146 ? 90.113  72.156 95.283  1.00 0.59 ? 146 ILE A C   1 
ATOM 1128 O O   . ILE A 1 146 ? 89.120  72.216 94.562  1.00 0.59 ? 146 ILE A O   1 
ATOM 1129 C CB  . ILE A 1 146 ? 89.977  69.974 96.368  1.00 0.59 ? 146 ILE A CB  1 
ATOM 1130 C CG1 . ILE A 1 146 ? 89.729  70.579 97.779  1.00 0.59 ? 146 ILE A CG1 1 
ATOM 1131 C CG2 . ILE A 1 146 ? 90.627  68.574 96.421  1.00 0.59 ? 146 ILE A CG2 1 
ATOM 1132 C CD1 . ILE A 1 146 ? 88.832  69.722 98.682  1.00 0.59 ? 146 ILE A CD1 1 
ATOM 1133 N N   . GLY A 1 147 ? 90.576  73.254 95.920  1.00 0.58 ? 147 GLY A N   1 
ATOM 1134 C CA  . GLY A 1 147 ? 89.818  74.493 95.869  1.00 0.58 ? 147 GLY A CA  1 
ATOM 1135 C C   . GLY A 1 147 ? 89.950  75.175 94.565  1.00 0.58 ? 147 GLY A C   1 
ATOM 1136 O O   . GLY A 1 147 ? 88.943  75.495 93.939  1.00 0.58 ? 147 GLY A O   1 
ATOM 1137 N N   . THR A 1 148 ? 91.198  75.419 94.117  1.00 0.52 ? 148 THR A N   1 
ATOM 1138 C CA  . THR A 1 148 ? 91.455  76.193 92.923  1.00 0.52 ? 148 THR A CA  1 
ATOM 1139 C C   . THR A 1 148 ? 92.819  75.826 92.275  1.00 0.52 ? 148 THR A C   1 
ATOM 1140 O O   . THR A 1 148 ? 93.516  74.942 92.778  1.00 0.52 ? 148 THR A O   1 
ATOM 1141 C CB  . THR A 1 148 ? 91.281  77.704 93.101  1.00 0.52 ? 148 THR A CB  1 
ATOM 1142 O OG1 . THR A 1 148 ? 92.360  78.218 93.781  1.00 0.52 ? 148 THR A OG1 1 
ATOM 1143 C CG2 . THR A 1 148 ? 90.014  78.214 93.837  1.00 0.52 ? 148 THR A CG2 1 
ATOM 1144 N N   . ARG A 1 149 ? 93.250  76.416 91.115  1.00 0.44 ? 149 ARG A N   1 
ATOM 1145 C CA  . ARG A 1 149 ? 94.495  76.140 90.369  1.00 0.44 ? 149 ARG A CA  1 
ATOM 1146 C C   . ARG A 1 149 ? 95.760  76.635 91.045  1.00 0.44 ? 149 ARG A C   1 
ATOM 1147 O O   . ARG A 1 149 ? 96.013  77.828 91.194  1.00 0.44 ? 149 ARG A O   1 
ATOM 1148 C CB  . ARG A 1 149 ? 94.474  76.804 88.954  1.00 0.44 ? 149 ARG A CB  1 
ATOM 1149 C CG  . ARG A 1 149 ? 95.605  76.551 87.927  1.00 0.44 ? 149 ARG A CG  1 
ATOM 1150 C CD  . ARG A 1 149 ? 95.362  77.332 86.617  1.00 0.44 ? 149 ARG A CD  1 
ATOM 1151 N NE  . ARG A 1 149 ? 94.216  76.692 85.890  1.00 0.44 ? 149 ARG A NE  1 
ATOM 1152 C CZ  . ARG A 1 149 ? 93.441  77.274 84.964  1.00 0.44 ? 149 ARG A CZ  1 
ATOM 1153 N NH1 . ARG A 1 149 ? 92.612  76.486 84.286  1.00 0.44 ? 149 ARG A NH1 1 
ATOM 1154 N NH2 . ARG A 1 149 ? 93.462  78.573 84.706  1.00 0.44 ? 149 ARG A NH2 1 
ATOM 1155 N N   . ASN A 1 150 ? 96.649  75.691 91.379  1.00 0.45 ? 150 ASN A N   1 
ATOM 1156 C CA  . ASN A 1 150 ? 97.957  75.965 91.910  1.00 0.45 ? 150 ASN A CA  1 
ATOM 1157 C C   . ASN A 1 150 ? 98.854  74.865 91.384  1.00 0.45 ? 150 ASN A C   1 
ATOM 1158 O O   . ASN A 1 150 ? 98.326  73.816 91.018  1.00 0.45 ? 150 ASN A O   1 
ATOM 1159 C CB  . ASN A 1 150 ? 97.943  75.885 93.450  1.00 0.45 ? 150 ASN A CB  1 
ATOM 1160 C CG  . ASN A 1 150 ? 97.491  77.211 94.030  1.00 0.45 ? 150 ASN A CG  1 
ATOM 1161 O OD1 . ASN A 1 150 ? 96.366  77.331 94.499  1.00 0.45 ? 150 ASN A OD1 1 
ATOM 1162 N ND2 . ASN A 1 150 ? 98.378  78.232 94.044  1.00 0.45 ? 150 ASN A ND2 1 
ATOM 1163 N N   . PRO A 1 151 ? 100.181 75.009 91.355  1.00 0.33 ? 151 PRO A N   1 
ATOM 1164 C CA  . PRO A 1 151 ? 101.078 74.023 90.744  1.00 0.33 ? 151 PRO A CA  1 
ATOM 1165 C C   . PRO A 1 151 ? 101.138 72.667 91.426  1.00 0.33 ? 151 PRO A C   1 
ATOM 1166 O O   . PRO A 1 151 ? 101.762 71.757 90.893  1.00 0.33 ? 151 PRO A O   1 
ATOM 1167 C CB  . PRO A 1 151 ? 102.460 74.688 90.839  1.00 0.33 ? 151 PRO A CB  1 
ATOM 1168 C CG  . PRO A 1 151 ? 102.167 76.186 90.812  1.00 0.33 ? 151 PRO A CG  1 
ATOM 1169 C CD  . PRO A 1 151 ? 100.864 76.286 91.595  1.00 0.33 ? 151 PRO A CD  1 
ATOM 1170 N N   . ALA A 1 152 ? 100.505 72.510 92.601  1.00 0.39 ? 152 ALA A N   1 
ATOM 1171 C CA  . ALA A 1 152 ? 100.392 71.267 93.323  1.00 0.39 ? 152 ALA A CA  1 
ATOM 1172 C C   . ALA A 1 152 ? 99.414  70.280 92.683  1.00 0.39 ? 152 ALA A C   1 
ATOM 1173 O O   . ALA A 1 152 ? 99.390  69.109 93.054  1.00 0.39 ? 152 ALA A O   1 
ATOM 1174 C CB  . ALA A 1 152 ? 99.915  71.585 94.756  1.00 0.39 ? 152 ALA A CB  1 
ATOM 1175 N N   . ASN A 1 153 ? 98.571  70.727 91.728  1.00 0.47 ? 153 ASN A N   1 
ATOM 1176 C CA  . ASN A 1 153 ? 97.568  69.893 91.101  1.00 0.47 ? 153 ASN A CA  1 
ATOM 1177 C C   . ASN A 1 153 ? 97.518  70.191 89.604  1.00 0.47 ? 153 ASN A C   1 
ATOM 1178 O O   . ASN A 1 153 ? 98.031  71.203 89.127  1.00 0.47 ? 153 ASN A O   1 
ATOM 1179 C CB  . ASN A 1 153 ? 96.194  70.170 91.775  1.00 0.47 ? 153 ASN A CB  1 
ATOM 1180 C CG  . ASN A 1 153 ? 95.154  69.087 91.501  1.00 0.47 ? 153 ASN A CG  1 
ATOM 1181 O OD1 . ASN A 1 153 ? 95.421  68.052 90.886  1.00 0.47 ? 153 ASN A OD1 1 
ATOM 1182 N ND2 . ASN A 1 153 ? 93.917  69.313 91.996  1.00 0.47 ? 153 ASN A ND2 1 
ATOM 1183 N N   . ASN A 1 154 ? 96.876  69.297 88.821  1.00 0.45 ? 154 ASN A N   1 
ATOM 1184 C CA  . ASN A 1 154 ? 96.578  69.491 87.411  1.00 0.45 ? 154 ASN A CA  1 
ATOM 1185 C C   . ASN A 1 154 ? 95.683  70.706 87.189  1.00 0.45 ? 154 ASN A C   1 
ATOM 1186 O O   . ASN A 1 154 ? 94.833  71.044 88.007  1.00 0.45 ? 154 ASN A O   1 
ATOM 1187 C CB  . ASN A 1 154 ? 95.922  68.239 86.774  1.00 0.45 ? 154 ASN A CB  1 
ATOM 1188 C CG  . ASN A 1 154 ? 96.921  67.090 86.783  1.00 0.45 ? 154 ASN A CG  1 
ATOM 1189 O OD1 . ASN A 1 154 ? 98.095  67.264 86.462  1.00 0.45 ? 154 ASN A OD1 1 
ATOM 1190 N ND2 . ASN A 1 154 ? 96.454  65.869 87.126  1.00 0.45 ? 154 ASN A ND2 1 
ATOM 1191 N N   . ALA A 1 155 ? 95.852  71.415 86.055  1.00 0.45 ? 155 ALA A N   1 
ATOM 1192 C CA  . ALA A 1 155 ? 95.317  72.756 85.893  1.00 0.45 ? 155 ALA A CA  1 
ATOM 1193 C C   . ALA A 1 155 ? 93.804  72.882 85.662  1.00 0.45 ? 155 ALA A C   1 
ATOM 1194 O O   . ALA A 1 155 ? 93.281  73.996 85.536  1.00 0.45 ? 155 ALA A O   1 
ATOM 1195 C CB  . ALA A 1 155 ? 96.084  73.449 84.747  1.00 0.45 ? 155 ALA A CB  1 
ATOM 1196 N N   . ALA A 1 156 ? 93.064  71.760 85.592  1.00 0.53 ? 156 ALA A N   1 
ATOM 1197 C CA  . ALA A 1 156 ? 91.632  71.761 85.425  1.00 0.53 ? 156 ALA A CA  1 
ATOM 1198 C C   . ALA A 1 156 ? 91.026  70.491 86.004  1.00 0.53 ? 156 ALA A C   1 
ATOM 1199 O O   . ALA A 1 156 ? 91.660  69.437 85.987  1.00 0.53 ? 156 ALA A O   1 
ATOM 1200 C CB  . ALA A 1 156 ? 91.263  71.858 83.929  1.00 0.53 ? 156 ALA A CB  1 
ATOM 1201 N N   . ILE A 1 157 ? 89.773  70.574 86.500  1.00 0.57 ? 157 ILE A N   1 
ATOM 1202 C CA  . ILE A 1 157 ? 89.046  69.479 87.124  1.00 0.57 ? 157 ILE A CA  1 
ATOM 1203 C C   . ILE A 1 157 ? 87.805  69.160 86.306  1.00 0.57 ? 157 ILE A C   1 
ATOM 1204 O O   . ILE A 1 157 ? 86.965  70.028 86.067  1.00 0.57 ? 157 ILE A O   1 
ATOM 1205 C CB  . ILE A 1 157 ? 88.549  69.845 88.521  1.00 0.57 ? 157 ILE A CB  1 
ATOM 1206 C CG1 . ILE A 1 157 ? 89.669  70.358 89.459  1.00 0.57 ? 157 ILE A CG1 1 
ATOM 1207 C CG2 . ILE A 1 157 ? 87.768  68.674 89.166  1.00 0.57 ? 157 ILE A CG2 1 
ATOM 1208 C CD1 . ILE A 1 157 ? 90.800  69.366 89.735  1.00 0.57 ? 157 ILE A CD1 1 
ATOM 1209 N N   . VAL A 1 158 ? 87.650  67.891 85.877  1.00 0.60 ? 158 VAL A N   1 
ATOM 1210 C CA  . VAL A 1 158 ? 86.485  67.412 85.138  1.00 0.60 ? 158 VAL A CA  1 
ATOM 1211 C C   . VAL A 1 158 ? 85.505  66.769 86.102  1.00 0.60 ? 158 VAL A C   1 
ATOM 1212 O O   . VAL A 1 158 ? 85.875  65.919 86.910  1.00 0.60 ? 158 VAL A O   1 
ATOM 1213 C CB  . VAL A 1 158 ? 86.850  66.405 84.037  1.00 0.60 ? 158 VAL A CB  1 
ATOM 1214 C CG1 . VAL A 1 158 ? 85.642  65.597 83.501  1.00 0.60 ? 158 VAL A CG1 1 
ATOM 1215 C CG2 . VAL A 1 158 ? 87.482  67.178 82.868  1.00 0.60 ? 158 VAL A CG2 1 
ATOM 1216 N N   . LEU A 1 159 ? 84.223  67.165 86.007  1.00 0.61 ? 159 LEU A N   1 
ATOM 1217 C CA  . LEU A 1 159 ? 83.108  66.585 86.718  1.00 0.61 ? 159 LEU A CA  1 
ATOM 1218 C C   . LEU A 1 159 ? 82.088  66.110 85.683  1.00 0.61 ? 159 LEU A C   1 
ATOM 1219 O O   . LEU A 1 159 ? 81.889  66.755 84.651  1.00 0.61 ? 159 LEU A O   1 
ATOM 1220 C CB  . LEU A 1 159 ? 82.481  67.599 87.712  1.00 0.61 ? 159 LEU A CB  1 
ATOM 1221 C CG  . LEU A 1 159 ? 83.488  68.159 88.747  1.00 0.61 ? 159 LEU A CG  1 
ATOM 1222 C CD1 . LEU A 1 159 ? 84.110  69.498 88.304  1.00 0.61 ? 159 LEU A CD1 1 
ATOM 1223 C CD2 . LEU A 1 159 ? 82.842  68.327 90.131  1.00 0.61 ? 159 LEU A CD2 1 
ATOM 1224 N N   . GLN A 1 160 ? 81.461  64.929 85.885  1.00 0.63 ? 160 GLN A N   1 
ATOM 1225 C CA  . GLN A 1 160 ? 80.575  64.343 84.897  1.00 0.63 ? 160 GLN A CA  1 
ATOM 1226 C C   . GLN A 1 160 ? 79.676  63.285 85.513  1.00 0.63 ? 160 GLN A C   1 
ATOM 1227 O O   . GLN A 1 160 ? 79.886  62.863 86.649  1.00 0.63 ? 160 GLN A O   1 
ATOM 1228 C CB  . GLN A 1 160 ? 81.391  63.705 83.736  1.00 0.63 ? 160 GLN A CB  1 
ATOM 1229 C CG  . GLN A 1 160 ? 82.365  62.593 84.195  1.00 0.63 ? 160 GLN A CG  1 
ATOM 1230 C CD  . GLN A 1 160 ? 83.344  62.193 83.093  1.00 0.63 ? 160 GLN A CD  1 
ATOM 1231 O OE1 . GLN A 1 160 ? 83.073  62.281 81.892  1.00 0.63 ? 160 GLN A OE1 1 
ATOM 1232 N NE2 . GLN A 1 160 ? 84.538  61.729 83.528  1.00 0.63 ? 160 GLN A NE2 1 
ATOM 1233 N N   . LEU A 1 161 ? 78.648  62.828 84.756  1.00 0.60 ? 161 LEU A N   1 
ATOM 1234 C CA  . LEU A 1 161 ? 77.683  61.820 85.171  1.00 0.60 ? 161 LEU A CA  1 
ATOM 1235 C C   . LEU A 1 161 ? 78.304  60.480 85.610  1.00 0.60 ? 161 LEU A C   1 
ATOM 1236 O O   . LEU A 1 161 ? 79.135  59.942 84.871  1.00 0.60 ? 161 LEU A O   1 
ATOM 1237 C CB  . LEU A 1 161 ? 76.703  61.490 84.007  1.00 0.60 ? 161 LEU A CB  1 
ATOM 1238 C CG  . LEU A 1 161 ? 75.797  62.649 83.539  1.00 0.60 ? 161 LEU A CG  1 
ATOM 1239 C CD1 . LEU A 1 161 ? 75.070  62.279 82.233  1.00 0.60 ? 161 LEU A CD1 1 
ATOM 1240 C CD2 . LEU A 1 161 ? 74.775  63.053 84.614  1.00 0.60 ? 161 LEU A CD2 1 
ATOM 1241 N N   . PRO A 1 162 ? 77.921  59.843 86.721  1.00 0.58 ? 162 PRO A N   1 
ATOM 1242 C CA  . PRO A 1 162 ? 78.619  58.660 87.232  1.00 0.58 ? 162 PRO A CA  1 
ATOM 1243 C C   . PRO A 1 162 ? 78.044  57.393 86.612  1.00 0.58 ? 162 PRO A C   1 
ATOM 1244 O O   . PRO A 1 162 ? 77.731  56.434 87.314  1.00 0.58 ? 162 PRO A O   1 
ATOM 1245 C CB  . PRO A 1 162 ? 78.341  58.730 88.748  1.00 0.58 ? 162 PRO A CB  1 
ATOM 1246 C CG  . PRO A 1 162 ? 76.981  59.421 88.862  1.00 0.58 ? 162 PRO A CG  1 
ATOM 1247 C CD  . PRO A 1 162 ? 77.013  60.420 87.712  1.00 0.58 ? 162 PRO A CD  1 
ATOM 1248 N N   . GLN A 1 163 ? 77.902  57.383 85.272  1.00 0.49 ? 163 GLN A N   1 
ATOM 1249 C CA  . GLN A 1 163 ? 77.337  56.316 84.459  1.00 0.49 ? 163 GLN A CA  1 
ATOM 1250 C C   . GLN A 1 163 ? 75.898  55.921 84.824  1.00 0.49 ? 163 GLN A C   1 
ATOM 1251 O O   . GLN A 1 163 ? 75.430  54.823 84.511  1.00 0.49 ? 163 GLN A O   1 
ATOM 1252 C CB  . GLN A 1 163 ? 78.283  55.086 84.374  1.00 0.49 ? 163 GLN A CB  1 
ATOM 1253 C CG  . GLN A 1 163 ? 79.713  55.431 83.889  1.00 0.49 ? 163 GLN A CG  1 
ATOM 1254 C CD  . GLN A 1 163 ? 80.592  54.187 83.749  1.00 0.49 ? 163 GLN A CD  1 
ATOM 1255 O OE1 . GLN A 1 163 ? 81.350  53.812 84.643  1.00 0.49 ? 163 GLN A OE1 1 
ATOM 1256 N NE2 . GLN A 1 163 ? 80.506  53.518 82.576  1.00 0.49 ? 163 GLN A NE2 1 
ATOM 1257 N N   . GLY A 1 164 ? 75.136  56.830 85.462  1.00 0.54 ? 164 GLY A N   1 
ATOM 1258 C CA  . GLY A 1 164 ? 73.818  56.552 86.000  1.00 0.54 ? 164 GLY A CA  1 
ATOM 1259 C C   . GLY A 1 164 ? 73.378  57.742 86.802  1.00 0.54 ? 164 GLY A C   1 
ATOM 1260 O O   . GLY A 1 164 ? 74.098  58.736 86.861  1.00 0.54 ? 164 GLY A O   1 
ATOM 1261 N N   . THR A 1 165 ? 72.171  57.659 87.411  1.00 0.52 ? 165 THR A N   1 
ATOM 1262 C CA  . THR A 1 165 ? 71.542  58.671 88.278  1.00 0.52 ? 165 THR A CA  1 
ATOM 1263 C C   . THR A 1 165 ? 71.502  60.056 87.652  1.00 0.52 ? 165 THR A C   1 
ATOM 1264 O O   . THR A 1 165 ? 71.937  61.059 88.214  1.00 0.52 ? 165 THR A O   1 
ATOM 1265 C CB  . THR A 1 165 ? 72.069  58.654 89.711  1.00 0.52 ? 165 THR A CB  1 
ATOM 1266 O OG1 . THR A 1 165 ? 72.010  57.323 90.208  1.00 0.52 ? 165 THR A OG1 1 
ATOM 1267 C CG2 . THR A 1 165 ? 71.221  59.458 90.710  1.00 0.52 ? 165 THR A CG2 1 
ATOM 1268 N N   . THR A 1 166 ? 70.989  60.137 86.407  1.00 0.56 ? 166 THR A N   1 
ATOM 1269 C CA  . THR A 1 166 ? 71.085  61.340 85.596  1.00 0.56 ? 166 THR A CA  1 
ATOM 1270 C C   . THR A 1 166 ? 69.993  62.349 85.896  1.00 0.56 ? 166 THR A C   1 
ATOM 1271 O O   . THR A 1 166 ? 68.935  62.044 86.445  1.00 0.56 ? 166 THR A O   1 
ATOM 1272 C CB  . THR A 1 166 ? 71.133  61.085 84.082  1.00 0.56 ? 166 THR A CB  1 
ATOM 1273 O OG1 . THR A 1 166 ? 69.896  60.627 83.559  1.00 0.56 ? 166 THR A OG1 1 
ATOM 1274 C CG2 . THR A 1 166 ? 72.173  60.000 83.755  1.00 0.56 ? 166 THR A CG2 1 
ATOM 1275 N N   . LEU A 1 167 ? 70.247  63.624 85.549  1.00 0.54 ? 167 LEU A N   1 
ATOM 1276 C CA  . LEU A 1 167 ? 69.249  64.675 85.533  1.00 0.54 ? 167 LEU A CA  1 
ATOM 1277 C C   . LEU A 1 167 ? 68.153  64.472 84.479  1.00 0.54 ? 167 LEU A C   1 
ATOM 1278 O O   . LEU A 1 167 ? 68.422  63.875 83.434  1.00 0.54 ? 167 LEU A O   1 
ATOM 1279 C CB  . LEU A 1 167 ? 69.943  66.032 85.294  1.00 0.54 ? 167 LEU A CB  1 
ATOM 1280 C CG  . LEU A 1 167 ? 70.780  66.505 86.494  1.00 0.54 ? 167 LEU A CG  1 
ATOM 1281 C CD1 . LEU A 1 167 ? 71.781  67.578 86.051  1.00 0.54 ? 167 LEU A CD1 1 
ATOM 1282 C CD2 . LEU A 1 167 ? 69.875  67.017 87.632  1.00 0.54 ? 167 LEU A CD2 1 
ATOM 1283 N N   . PRO A 1 168 ? 66.915  64.926 84.692  1.00 0.42 ? 168 PRO A N   1 
ATOM 1284 C CA  . PRO A 1 168 ? 65.828  64.747 83.741  1.00 0.42 ? 168 PRO A CA  1 
ATOM 1285 C C   . PRO A 1 168 ? 65.995  65.507 82.434  1.00 0.42 ? 168 PRO A C   1 
ATOM 1286 O O   . PRO A 1 168 ? 66.945  66.259 82.233  1.00 0.42 ? 168 PRO A O   1 
ATOM 1287 C CB  . PRO A 1 168 ? 64.580  65.181 84.525  1.00 0.42 ? 168 PRO A CB  1 
ATOM 1288 C CG  . PRO A 1 168 ? 65.101  66.216 85.516  1.00 0.42 ? 168 PRO A CG  1 
ATOM 1289 C CD  . PRO A 1 168 ? 66.485  65.685 85.872  1.00 0.42 ? 168 PRO A CD  1 
ATOM 1290 N N   . LYS A 1 169 ? 65.034  65.292 81.514  1.00 0.35 ? 169 LYS A N   1 
ATOM 1291 C CA  . LYS A 1 169 ? 65.108  65.564 80.088  1.00 0.35 ? 169 LYS A CA  1 
ATOM 1292 C C   . LYS A 1 169 ? 65.393  66.997 79.641  1.00 0.35 ? 169 LYS A C   1 
ATOM 1293 O O   . LYS A 1 169 ? 65.842  67.219 78.520  1.00 0.35 ? 169 LYS A O   1 
ATOM 1294 C CB  . LYS A 1 169 ? 63.789  65.070 79.437  1.00 0.35 ? 169 LYS A CB  1 
ATOM 1295 C CG  . LYS A 1 169 ? 63.824  64.919 77.905  1.00 0.35 ? 169 LYS A CG  1 
ATOM 1296 C CD  . LYS A 1 169 ? 62.486  64.453 77.304  1.00 0.35 ? 169 LYS A CD  1 
ATOM 1297 C CE  . LYS A 1 169 ? 62.081  63.035 77.723  1.00 0.35 ? 169 LYS A CE  1 
ATOM 1298 N NZ  . LYS A 1 169 ? 60.770  62.668 77.137  1.00 0.35 ? 169 LYS A NZ  1 
ATOM 1299 N N   . GLY A 1 170 ? 65.138  68.011 80.492  1.00 0.45 ? 170 GLY A N   1 
ATOM 1300 C CA  . GLY A 1 170 ? 65.472  69.395 80.166  1.00 0.45 ? 170 GLY A CA  1 
ATOM 1301 C C   . GLY A 1 170 ? 66.954  69.688 80.136  1.00 0.45 ? 170 GLY A C   1 
ATOM 1302 O O   . GLY A 1 170 ? 67.441  70.436 79.294  1.00 0.45 ? 170 GLY A O   1 
ATOM 1303 N N   . PHE A 1 171 ? 67.708  69.107 81.083  1.00 0.47 ? 171 PHE A N   1 
ATOM 1304 C CA  . PHE A 1 171 ? 69.076  69.492 81.361  1.00 0.47 ? 171 PHE A CA  1 
ATOM 1305 C C   . PHE A 1 171 ? 70.122  69.162 80.291  1.00 0.47 ? 171 PHE A C   1 
ATOM 1306 O O   . PHE A 1 171 ? 70.311  68.024 79.862  1.00 0.47 ? 171 PHE A O   1 
ATOM 1307 C CB  . PHE A 1 171 ? 69.568  68.888 82.705  1.00 0.47 ? 171 PHE A CB  1 
ATOM 1308 C CG  . PHE A 1 171 ? 68.860  69.451 83.917  1.00 0.47 ? 171 PHE A CG  1 
ATOM 1309 C CD1 . PHE A 1 171 ? 67.605  68.970 84.330  1.00 0.47 ? 171 PHE A CD1 1 
ATOM 1310 C CD2 . PHE A 1 171 ? 69.503  70.407 84.719  1.00 0.47 ? 171 PHE A CD2 1 
ATOM 1311 C CE1 . PHE A 1 171 ? 67.017  69.417 85.520  1.00 0.47 ? 171 PHE A CE1 1 
ATOM 1312 C CE2 . PHE A 1 171 ? 68.921  70.846 85.915  1.00 0.47 ? 171 PHE A CE2 1 
ATOM 1313 C CZ  . PHE A 1 171 ? 67.684  70.344 86.320  1.00 0.47 ? 171 PHE A CZ  1 
ATOM 1314 N N   . TYR A 1 172 ? 70.935  70.175 79.918  1.00 0.44 ? 172 TYR A N   1 
ATOM 1315 C CA  . TYR A 1 172 ? 72.234  69.972 79.307  1.00 0.44 ? 172 TYR A CA  1 
ATOM 1316 C C   . TYR A 1 172 ? 73.184  69.657 80.461  1.00 0.44 ? 172 TYR A C   1 
ATOM 1317 O O   . TYR A 1 172 ? 73.515  70.540 81.250  1.00 0.44 ? 172 TYR A O   1 
ATOM 1318 C CB  . TYR A 1 172 ? 72.660  71.262 78.533  1.00 0.44 ? 172 TYR A CB  1 
ATOM 1319 C CG  . TYR A 1 172 ? 73.935  71.156 77.733  1.00 0.44 ? 172 TYR A CG  1 
ATOM 1320 C CD1 . TYR A 1 172 ? 75.191  71.138 78.361  1.00 0.44 ? 172 TYR A CD1 1 
ATOM 1321 C CD2 . TYR A 1 172 ? 73.892  71.114 76.329  1.00 0.44 ? 172 TYR A CD2 1 
ATOM 1322 C CE1 . TYR A 1 172 ? 76.368  70.978 77.617  1.00 0.44 ? 172 TYR A CE1 1 
ATOM 1323 C CE2 . TYR A 1 172 ? 75.069  70.977 75.581  1.00 0.44 ? 172 TYR A CE2 1 
ATOM 1324 C CZ  . TYR A 1 172 ? 76.305  70.876 76.227  1.00 0.44 ? 172 TYR A CZ  1 
ATOM 1325 O OH  . TYR A 1 172 ? 77.479  70.723 75.464  1.00 0.44 ? 172 TYR A OH  1 
ATOM 1326 N N   . ALA A 1 173 ? 73.574  68.368 80.603  1.00 0.63 ? 173 ALA A N   1 
ATOM 1327 C CA  . ALA A 1 173 ? 74.503  67.835 81.592  1.00 0.63 ? 173 ALA A CA  1 
ATOM 1328 C C   . ALA A 1 173 ? 75.894  68.471 81.579  1.00 0.63 ? 173 ALA A C   1 
ATOM 1329 O O   . ALA A 1 173 ? 76.202  69.290 80.722  1.00 0.63 ? 173 ALA A O   1 
ATOM 1330 C CB  . ALA A 1 173 ? 74.588  66.299 81.438  1.00 0.63 ? 173 ALA A CB  1 
ATOM 1331 N N   . GLU A 1 174 ? 76.791  68.094 82.519  1.00 0.61 ? 174 GLU A N   1 
ATOM 1332 C CA  . GLU A 1 174 ? 78.039  68.780 82.802  1.00 0.61 ? 174 GLU A CA  1 
ATOM 1333 C C   . GLU A 1 174 ? 78.913  69.032 81.582  1.00 0.61 ? 174 GLU A C   1 
ATOM 1334 O O   . GLU A 1 174 ? 79.345  70.148 81.328  1.00 0.61 ? 174 GLU A O   1 
ATOM 1335 C CB  . GLU A 1 174 ? 78.851  68.036 83.898  1.00 0.61 ? 174 GLU A CB  1 
ATOM 1336 C CG  . GLU A 1 174 ? 78.167  68.014 85.287  1.00 0.61 ? 174 GLU A CG  1 
ATOM 1337 C CD  . GLU A 1 174 ? 77.135  66.894 85.437  1.00 0.61 ? 174 GLU A CD  1 
ATOM 1338 O OE1 . GLU A 1 174 ? 76.789  66.235 84.417  1.00 0.61 ? 174 GLU A OE1 1 
ATOM 1339 O OE2 . GLU A 1 174 ? 76.695  66.679 86.586  1.00 0.61 ? 174 GLU A OE2 1 
ATOM 1340 N N   . GLY A 1 175 ? 79.147  68.041 80.708  1.00 0.61 ? 175 GLY A N   1 
ATOM 1341 C CA  . GLY A 1 175 ? 79.570  68.420 79.358  1.00 0.61 ? 175 GLY A CA  1 
ATOM 1342 C C   . GLY A 1 175 ? 81.014  68.769 79.108  1.00 0.61 ? 175 GLY A C   1 
ATOM 1343 O O   . GLY A 1 175 ? 81.318  69.689 78.345  1.00 0.61 ? 175 GLY A O   1 
ATOM 1344 N N   . SER A 1 176 ? 81.950  67.993 79.697  1.00 0.55 ? 176 SER A N   1 
ATOM 1345 C CA  . SER A 1 176 ? 83.370  68.024 79.346  1.00 0.55 ? 176 SER A CA  1 
ATOM 1346 C C   . SER A 1 176 ? 83.624  67.821 77.853  1.00 0.55 ? 176 SER A C   1 
ATOM 1347 O O   . SER A 1 176 ? 83.040  66.940 77.218  1.00 0.55 ? 176 SER A O   1 
ATOM 1348 C CB  . SER A 1 176 ? 84.212  66.982 80.136  1.00 0.55 ? 176 SER A CB  1 
ATOM 1349 O OG  . SER A 1 176 ? 85.605  67.080 79.834  1.00 0.55 ? 176 SER A OG  1 
ATOM 1350 N N   . ARG A 1 177 ? 84.502  68.667 77.276  1.00 0.46 ? 177 ARG A N   1 
ATOM 1351 C CA  . ARG A 1 177 ? 84.813  68.713 75.867  1.00 0.46 ? 177 ARG A CA  1 
ATOM 1352 C C   . ARG A 1 177 ? 86.247  69.175 75.737  1.00 0.46 ? 177 ARG A C   1 
ATOM 1353 O O   . ARG A 1 177 ? 86.699  70.021 76.508  1.00 0.46 ? 177 ARG A O   1 
ATOM 1354 C CB  . ARG A 1 177 ? 83.942  69.746 75.100  1.00 0.46 ? 177 ARG A CB  1 
ATOM 1355 C CG  . ARG A 1 177 ? 82.485  69.297 74.879  1.00 0.46 ? 177 ARG A CG  1 
ATOM 1356 C CD  . ARG A 1 177 ? 81.591  70.347 74.214  1.00 0.46 ? 177 ARG A CD  1 
ATOM 1357 N NE  . ARG A 1 177 ? 81.343  71.416 75.234  1.00 0.46 ? 177 ARG A NE  1 
ATOM 1358 C CZ  . ARG A 1 177 ? 81.628  72.715 75.084  1.00 0.46 ? 177 ARG A CZ  1 
ATOM 1359 N NH1 . ARG A 1 177 ? 81.526  73.520 76.142  1.00 0.46 ? 177 ARG A NH1 1 
ATOM 1360 N NH2 . ARG A 1 177 ? 82.004  73.227 73.916  1.00 0.46 ? 177 ARG A NH2 1 
ATOM 1361 N N   . GLY A 1 178 ? 86.971  68.662 74.717  1.00 0.35 ? 178 GLY A N   1 
ATOM 1362 C CA  . GLY A 1 178 ? 88.424  68.792 74.569  1.00 0.35 ? 178 GLY A CA  1 
ATOM 1363 C C   . GLY A 1 178 ? 89.043  70.165 74.570  1.00 0.35 ? 178 GLY A C   1 
ATOM 1364 O O   . GLY A 1 178 ? 90.180  70.332 74.991  1.00 0.35 ? 178 GLY A O   1 
ATOM 1365 N N   . GLY A 1 179 ? 88.314  71.179 74.067  1.00 0.39 ? 179 GLY A N   1 
ATOM 1366 C CA  . GLY A 1 179 ? 88.782  72.560 74.042  1.00 0.39 ? 179 GLY A CA  1 
ATOM 1367 C C   . GLY A 1 179 ? 88.217  73.420 75.133  1.00 0.39 ? 179 GLY A C   1 
ATOM 1368 O O   . GLY A 1 179 ? 88.577  74.585 75.254  1.00 0.39 ? 179 GLY A O   1 
ATOM 1369 N N   . SER A 1 180 ? 87.300  72.880 75.959  1.00 0.40 ? 180 SER A N   1 
ATOM 1370 C CA  . SER A 1 180 ? 86.842  73.572 77.157  1.00 0.40 ? 180 SER A CA  1 
ATOM 1371 C C   . SER A 1 180 ? 87.846  73.333 78.269  1.00 0.40 ? 180 SER A C   1 
ATOM 1372 O O   . SER A 1 180 ? 88.338  74.268 78.891  1.00 0.40 ? 180 SER A O   1 
ATOM 1373 C CB  . SER A 1 180 ? 85.413  73.108 77.571  1.00 0.40 ? 180 SER A CB  1 
ATOM 1374 O OG  . SER A 1 180 ? 84.869  73.843 78.671  1.00 0.40 ? 180 SER A OG  1 
ATOM 1375 N N   . GLN A 1 181 ? 88.246  72.067 78.509  1.00 0.50 ? 181 GLN A N   1 
ATOM 1376 C CA  . GLN A 1 181 ? 89.310  71.781 79.447  1.00 0.50 ? 181 GLN A CA  1 
ATOM 1377 C C   . GLN A 1 181 ? 89.935  70.448 79.094  1.00 0.50 ? 181 GLN A C   1 
ATOM 1378 O O   . GLN A 1 181 ? 89.254  69.531 78.643  1.00 0.50 ? 181 GLN A O   1 
ATOM 1379 C CB  . GLN A 1 181 ? 88.816  71.744 80.920  1.00 0.50 ? 181 GLN A CB  1 
ATOM 1380 C CG  . GLN A 1 181 ? 87.434  71.057 81.054  1.00 0.50 ? 181 GLN A CG  1 
ATOM 1381 C CD  . GLN A 1 181 ? 86.935  70.744 82.471  1.00 0.50 ? 181 GLN A CD  1 
ATOM 1382 O OE1 . GLN A 1 181 ? 85.946  70.021 82.604  1.00 0.50 ? 181 GLN A OE1 1 
ATOM 1383 N NE2 . GLN A 1 181 ? 87.570  71.275 83.531  1.00 0.50 ? 181 GLN A NE2 1 
ATOM 1384 N N   . ALA A 1 182 ? 91.261  70.314 79.310  1.00 0.51 ? 182 ALA A N   1 
ATOM 1385 C CA  . ALA A 1 182 ? 91.999  69.148 78.863  1.00 0.51 ? 182 ALA A CA  1 
ATOM 1386 C C   . ALA A 1 182 ? 92.892  68.497 79.918  1.00 0.51 ? 182 ALA A C   1 
ATOM 1387 O O   . ALA A 1 182 ? 93.370  67.383 79.733  1.00 0.51 ? 182 ALA A O   1 
ATOM 1388 C CB  . ALA A 1 182 ? 92.909  69.609 77.714  1.00 0.51 ? 182 ALA A CB  1 
ATOM 1389 N N   . SER A 1 183 ? 93.171  69.168 81.052  1.00 0.55 ? 183 SER A N   1 
ATOM 1390 C CA  . SER A 1 183 ? 94.239  68.740 81.952  1.00 0.55 ? 183 SER A CA  1 
ATOM 1391 C C   . SER A 1 183 ? 93.908  67.606 82.903  1.00 0.55 ? 183 SER A C   1 
ATOM 1392 O O   . SER A 1 183 ? 94.793  66.976 83.478  1.00 0.55 ? 183 SER A O   1 
ATOM 1393 C CB  . SER A 1 183 ? 94.714  69.910 82.839  1.00 0.55 ? 183 SER A CB  1 
ATOM 1394 O OG  . SER A 1 183 ? 94.855  71.094 82.051  1.00 0.55 ? 183 SER A OG  1 
ATOM 1395 N N   . SER A 1 184 ? 92.613  67.338 83.111  1.00 0.61 ? 184 SER A N   1 
ATOM 1396 C CA  . SER A 1 184 ? 92.124  66.194 83.863  1.00 0.61 ? 184 SER A CA  1 
ATOM 1397 C C   . SER A 1 184 ? 92.137  64.928 83.025  1.00 0.61 ? 184 SER A C   1 
ATOM 1398 O O   . SER A 1 184 ? 91.940  64.952 81.813  1.00 0.61 ? 184 SER A O   1 
ATOM 1399 C CB  . SER A 1 184 ? 90.665  66.425 84.320  1.00 0.61 ? 184 SER A CB  1 
ATOM 1400 O OG  . SER A 1 184 ? 90.207  65.483 85.292  1.00 0.61 ? 184 SER A OG  1 
ATOM 1401 N N   . ARG A 1 185 ? 92.340  63.759 83.659  1.00 0.58 ? 185 ARG A N   1 
ATOM 1402 C CA  . ARG A 1 185 ? 92.080  62.477 83.034  1.00 0.58 ? 185 ARG A CA  1 
ATOM 1403 C C   . ARG A 1 185 ? 90.593  62.253 82.795  1.00 0.58 ? 185 ARG A C   1 
ATOM 1404 O O   . ARG A 1 185 ? 89.731  62.738 83.524  1.00 0.58 ? 185 ARG A O   1 
ATOM 1405 C CB  . ARG A 1 185 ? 92.616  61.288 83.873  1.00 0.58 ? 185 ARG A CB  1 
ATOM 1406 C CG  . ARG A 1 185 ? 94.140  61.326 84.111  1.00 0.58 ? 185 ARG A CG  1 
ATOM 1407 C CD  . ARG A 1 185 ? 94.700  60.167 84.950  1.00 0.58 ? 185 ARG A CD  1 
ATOM 1408 N NE  . ARG A 1 185 ? 94.664  58.931 84.100  1.00 0.58 ? 185 ARG A NE  1 
ATOM 1409 C CZ  . ARG A 1 185 ? 95.275  57.779 84.413  1.00 0.58 ? 185 ARG A CZ  1 
ATOM 1410 N NH1 . ARG A 1 185 ? 95.326  56.789 83.522  1.00 0.58 ? 185 ARG A NH1 1 
ATOM 1411 N NH2 . ARG A 1 185 ? 95.878  57.613 85.584  1.00 0.58 ? 185 ARG A NH2 1 
ATOM 1412 N N   . SER A 1 186 ? 90.242  61.447 81.776  1.00 0.63 ? 186 SER A N   1 
ATOM 1413 C CA  . SER A 1 186 ? 88.856  61.195 81.411  1.00 0.63 ? 186 SER A CA  1 
ATOM 1414 C C   . SER A 1 186 ? 88.081  60.334 82.407  1.00 0.63 ? 186 SER A C   1 
ATOM 1415 O O   . SER A 1 186 ? 86.852  60.355 82.438  1.00 0.63 ? 186 SER A O   1 
ATOM 1416 C CB  . SER A 1 186 ? 88.798  60.519 80.017  1.00 0.63 ? 186 SER A CB  1 
ATOM 1417 O OG  . SER A 1 186 ? 89.605  59.337 79.967  1.00 0.63 ? 186 SER A OG  1 
ATOM 1418 N N   . SER A 1 187 ? 88.802  59.561 83.245  1.00 0.64 ? 187 SER A N   1 
ATOM 1419 C CA  . SER A 1 187 ? 88.284  58.781 84.366  1.00 0.64 ? 187 SER A CA  1 
ATOM 1420 C C   . SER A 1 187 ? 87.542  57.508 83.949  1.00 0.64 ? 187 SER A C   1 
ATOM 1421 O O   . SER A 1 187 ? 86.959  56.804 84.762  1.00 0.64 ? 187 SER A O   1 
ATOM 1422 C CB  . SER A 1 187 ? 87.581  59.676 85.437  1.00 0.64 ? 187 SER A CB  1 
ATOM 1423 O OG  . SER A 1 187 ? 87.445  59.087 86.734  1.00 0.64 ? 187 SER A OG  1 
ATOM 1424 N N   . SER A 1 188 ? 87.687  57.081 82.668  1.00 0.64 ? 188 SER A N   1 
ATOM 1425 C CA  . SER A 1 188 ? 87.150  55.823 82.133  1.00 0.64 ? 188 SER A CA  1 
ATOM 1426 C C   . SER A 1 188 ? 87.913  54.585 82.585  1.00 0.64 ? 188 SER A C   1 
ATOM 1427 O O   . SER A 1 188 ? 87.513  53.445 82.360  1.00 0.64 ? 188 SER A O   1 
ATOM 1428 C CB  . SER A 1 188 ? 87.137  55.827 80.585  1.00 0.64 ? 188 SER A CB  1 
ATOM 1429 O OG  . SER A 1 188 ? 88.438  56.011 80.013  1.00 0.64 ? 188 SER A OG  1 
ATOM 1430 N N   . ARG A 1 189 ? 89.054  54.836 83.250  1.00 0.59 ? 189 ARG A N   1 
ATOM 1431 C CA  . ARG A 1 189 ? 89.951  53.919 83.919  1.00 0.59 ? 189 ARG A CA  1 
ATOM 1432 C C   . ARG A 1 189 ? 89.307  53.076 85.001  1.00 0.59 ? 189 ARG A C   1 
ATOM 1433 O O   . ARG A 1 189 ? 89.724  51.939 85.215  1.00 0.59 ? 189 ARG A O   1 
ATOM 1434 C CB  . ARG A 1 189 ? 91.057  54.780 84.593  1.00 0.59 ? 189 ARG A CB  1 
ATOM 1435 C CG  . ARG A 1 189 ? 92.128  54.025 85.421  1.00 0.59 ? 189 ARG A CG  1 
ATOM 1436 C CD  . ARG A 1 189 ? 93.151  54.931 86.125  1.00 0.59 ? 189 ARG A CD  1 
ATOM 1437 N NE  . ARG A 1 189 ? 92.447  55.741 87.190  1.00 0.59 ? 189 ARG A NE  1 
ATOM 1438 C CZ  . ARG A 1 189 ? 92.370  55.429 88.494  1.00 0.59 ? 189 ARG A CZ  1 
ATOM 1439 N NH1 . ARG A 1 189 ? 91.651  56.192 89.319  1.00 0.59 ? 189 ARG A NH1 1 
ATOM 1440 N NH2 . ARG A 1 189 ? 92.992  54.367 88.990  1.00 0.59 ? 189 ARG A NH2 1 
ATOM 1441 N N   . SER A 1 190 ? 88.332  53.638 85.738  1.00 0.58 ? 190 SER A N   1 
ATOM 1442 C CA  . SER A 1 190 ? 87.722  52.937 86.846  1.00 0.58 ? 190 SER A CA  1 
ATOM 1443 C C   . SER A 1 190 ? 86.236  53.176 86.798  1.00 0.58 ? 190 SER A C   1 
ATOM 1444 O O   . SER A 1 190 ? 85.773  54.266 87.120  1.00 0.58 ? 190 SER A O   1 
ATOM 1445 C CB  . SER A 1 190 ? 88.232  53.450 88.217  1.00 0.58 ? 190 SER A CB  1 
ATOM 1446 O OG  . SER A 1 190 ? 89.644  53.264 88.364  1.00 0.58 ? 190 SER A OG  1 
ATOM 1447 N N   . ARG A 1 191 ? 85.451  52.164 86.383  1.00 0.59 ? 191 ARG A N   1 
ATOM 1448 C CA  . ARG A 1 191 ? 84.005  52.271 86.253  1.00 0.59 ? 191 ARG A CA  1 
ATOM 1449 C C   . ARG A 1 191 ? 83.211  52.597 87.516  1.00 0.59 ? 191 ARG A C   1 
ATOM 1450 O O   . ARG A 1 191 ? 83.490  52.112 88.613  1.00 0.59 ? 191 ARG A O   1 
ATOM 1451 C CB  . ARG A 1 191 ? 83.397  51.011 85.582  1.00 0.59 ? 191 ARG A CB  1 
ATOM 1452 C CG  . ARG A 1 191 ? 83.566  49.685 86.360  1.00 0.59 ? 191 ARG A CG  1 
ATOM 1453 C CD  . ARG A 1 191 ? 82.901  48.504 85.645  1.00 0.59 ? 191 ARG A CD  1 
ATOM 1454 N NE  . ARG A 1 191 ? 83.292  47.235 86.358  1.00 0.59 ? 191 ARG A NE  1 
ATOM 1455 C CZ  . ARG A 1 191 ? 84.312  46.443 86.001  1.00 0.59 ? 191 ARG A CZ  1 
ATOM 1456 N NH1 . ARG A 1 191 ? 84.588  45.358 86.726  1.00 0.59 ? 191 ARG A NH1 1 
ATOM 1457 N NH2 . ARG A 1 191 ? 85.073  46.695 84.945  1.00 0.59 ? 191 ARG A NH2 1 
ATOM 1458 N N   . ASN A 1 192 ? 82.156  53.425 87.368  1.00 0.61 ? 192 ASN A N   1 
ATOM 1459 C CA  . ASN A 1 192 ? 81.243  53.761 88.442  1.00 0.61 ? 192 ASN A CA  1 
ATOM 1460 C C   . ASN A 1 192 ? 80.238  52.645 88.708  1.00 0.61 ? 192 ASN A C   1 
ATOM 1461 O O   . ASN A 1 192 ? 79.921  51.827 87.845  1.00 0.61 ? 192 ASN A O   1 
ATOM 1462 C CB  . ASN A 1 192 ? 80.449  55.053 88.131  1.00 0.61 ? 192 ASN A CB  1 
ATOM 1463 C CG  . ASN A 1 192 ? 81.359  56.266 87.998  1.00 0.61 ? 192 ASN A CG  1 
ATOM 1464 O OD1 . ASN A 1 192 ? 81.622  56.764 86.904  1.00 0.61 ? 192 ASN A OD1 1 
ATOM 1465 N ND2 . ASN A 1 192 ? 81.815  56.813 89.149  1.00 0.61 ? 192 ASN A ND2 1 
ATOM 1466 N N   . SER A 1 193 ? 79.696  52.582 89.942  1.00 0.57 ? 193 SER A N   1 
ATOM 1467 C CA  . SER A 1 193 ? 78.652  51.635 90.311  1.00 0.57 ? 193 SER A CA  1 
ATOM 1468 C C   . SER A 1 193 ? 77.323  51.894 89.613  1.00 0.57 ? 193 SER A C   1 
ATOM 1469 O O   . SER A 1 193 ? 76.569  52.784 90.003  1.00 0.57 ? 193 SER A O   1 
ATOM 1470 C CB  . SER A 1 193 ? 78.389  51.638 91.838  1.00 0.57 ? 193 SER A CB  1 
ATOM 1471 O OG  . SER A 1 193 ? 79.608  51.392 92.540  1.00 0.57 ? 193 SER A OG  1 
ATOM 1472 N N   . SER A 1 194 ? 76.984  51.112 88.570  1.00 0.62 ? 194 SER A N   1 
ATOM 1473 C CA  . SER A 1 194 ? 75.769  51.312 87.797  1.00 0.62 ? 194 SER A CA  1 
ATOM 1474 C C   . SER A 1 194 ? 75.355  49.993 87.187  1.00 0.62 ? 194 SER A C   1 
ATOM 1475 O O   . SER A 1 194 ? 76.186  49.118 86.960  1.00 0.62 ? 194 SER A O   1 
ATOM 1476 C CB  . SER A 1 194 ? 75.960  52.355 86.657  1.00 0.62 ? 194 SER A CB  1 
ATOM 1477 O OG  . SER A 1 194 ? 74.803  52.535 85.826  1.00 0.62 ? 194 SER A OG  1 
ATOM 1478 N N   . ARG A 1 195 ? 74.042  49.831 86.922  1.00 0.61 ? 195 ARG A N   1 
ATOM 1479 C CA  . ARG A 1 195 ? 73.465  48.668 86.283  1.00 0.61 ? 195 ARG A CA  1 
ATOM 1480 C C   . ARG A 1 195 ? 72.841  48.998 84.936  1.00 0.61 ? 195 ARG A C   1 
ATOM 1481 O O   . ARG A 1 195 ? 72.101  48.183 84.392  1.00 0.61 ? 195 ARG A O   1 
ATOM 1482 C CB  . ARG A 1 195 ? 72.333  48.071 87.168  1.00 0.61 ? 195 ARG A CB  1 
ATOM 1483 C CG  . ARG A 1 195 ? 71.097  48.976 87.413  1.00 0.61 ? 195 ARG A CG  1 
ATOM 1484 C CD  . ARG A 1 195 ? 70.050  48.303 88.312  1.00 0.61 ? 195 ARG A CD  1 
ATOM 1485 N NE  . ARG A 1 195 ? 68.927  49.277 88.570  1.00 0.61 ? 195 ARG A NE  1 
ATOM 1486 C CZ  . ARG A 1 195 ? 67.776  49.334 87.883  1.00 0.61 ? 195 ARG A CZ  1 
ATOM 1487 N NH1 . ARG A 1 195 ? 66.821  50.176 88.278  1.00 0.61 ? 195 ARG A NH1 1 
ATOM 1488 N NH2 . ARG A 1 195 ? 67.556  48.568 86.820  1.00 0.61 ? 195 ARG A NH2 1 
ATOM 1489 N N   . ASN A 1 196 ? 73.051  50.219 84.393  1.00 0.71 ? 196 ASN A N   1 
ATOM 1490 C CA  . ASN A 1 196 ? 72.226  50.707 83.299  1.00 0.71 ? 196 ASN A CA  1 
ATOM 1491 C C   . ASN A 1 196 ? 72.887  50.689 81.929  1.00 0.71 ? 196 ASN A C   1 
ATOM 1492 O O   . ASN A 1 196 ? 72.293  51.134 80.953  1.00 0.71 ? 196 ASN A O   1 
ATOM 1493 C CB  . ASN A 1 196 ? 71.764  52.145 83.653  1.00 0.71 ? 196 ASN A CB  1 
ATOM 1494 C CG  . ASN A 1 196 ? 70.457  52.494 82.957  1.00 0.71 ? 196 ASN A CG  1 
ATOM 1495 O OD1 . ASN A 1 196 ? 69.559  51.658 82.867  1.00 0.71 ? 196 ASN A OD1 1 
ATOM 1496 N ND2 . ASN A 1 196 ? 70.294  53.765 82.534  1.00 0.71 ? 196 ASN A ND2 1 
ATOM 1497 N N   . SER A 1 197 ? 74.131  50.192 81.808  1.00 0.72 ? 197 SER A N   1 
ATOM 1498 C CA  . SER A 1 197 ? 74.706  49.822 80.514  1.00 0.72 ? 197 SER A CA  1 
ATOM 1499 C C   . SER A 1 197 ? 74.911  50.952 79.505  1.00 0.72 ? 197 SER A C   1 
ATOM 1500 O O   . SER A 1 197 ? 74.855  50.741 78.294  1.00 0.72 ? 197 SER A O   1 
ATOM 1501 C CB  . SER A 1 197 ? 73.873  48.732 79.784  1.00 0.72 ? 197 SER A CB  1 
ATOM 1502 O OG  . SER A 1 197 ? 73.236  47.791 80.648  1.00 0.72 ? 197 SER A OG  1 
ATOM 1503 N N   . THR A 1 198 ? 75.142  52.198 79.978  1.00 0.77 ? 198 THR A N   1 
ATOM 1504 C CA  . THR A 1 198 ? 75.384  53.405 79.162  1.00 0.77 ? 198 THR A CA  1 
ATOM 1505 C C   . THR A 1 198 ? 74.447  53.638 77.954  1.00 0.77 ? 198 THR A C   1 
ATOM 1506 O O   . THR A 1 198 ? 74.899  53.636 76.802  1.00 0.77 ? 198 THR A O   1 
ATOM 1507 C CB  . THR A 1 198 ? 76.859  53.637 78.805  1.00 0.77 ? 198 THR A CB  1 
ATOM 1508 O OG1 . THR A 1 198 ? 77.500  52.458 78.339  1.00 0.77 ? 198 THR A OG1 1 
ATOM 1509 C CG2 . THR A 1 198 ? 77.616  54.061 80.079  1.00 0.77 ? 198 THR A CG2 1 
ATOM 1510 N N   . PRO A 1 199 ? 73.126  53.821 78.134  1.00 0.75 ? 199 PRO A N   1 
ATOM 1511 C CA  . PRO A 1 199 ? 72.170  54.039 77.045  1.00 0.75 ? 199 PRO A CA  1 
ATOM 1512 C C   . PRO A 1 199 ? 72.391  55.276 76.186  1.00 0.75 ? 199 PRO A C   1 
ATOM 1513 O O   . PRO A 1 199 ? 73.128  56.181 76.572  1.00 0.75 ? 199 PRO A O   1 
ATOM 1514 C CB  . PRO A 1 199 ? 70.798  54.126 77.741  1.00 0.75 ? 199 PRO A CB  1 
ATOM 1515 C CG  . PRO A 1 199 ? 71.028  53.565 79.137  1.00 0.75 ? 199 PRO A CG  1 
ATOM 1516 C CD  . PRO A 1 199 ? 72.461  53.983 79.428  1.00 0.75 ? 199 PRO A CD  1 
ATOM 1517 N N   . GLY A 1 200 ? 71.737  55.325 75.001  1.00 0.75 ? 200 GLY A N   1 
ATOM 1518 C CA  . GLY A 1 200 ? 71.737  56.484 74.110  1.00 0.75 ? 200 GLY A CA  1 
ATOM 1519 C C   . GLY A 1 200 ? 70.580  57.427 74.326  1.00 0.75 ? 200 GLY A C   1 
ATOM 1520 O O   . GLY A 1 200 ? 70.051  57.569 75.421  1.00 0.75 ? 200 GLY A O   1 
ATOM 1521 N N   . SER A 1 201 ? 70.130  58.098 73.249  1.00 0.21 ? 201 SER A N   1 
ATOM 1522 C CA  . SER A 1 201 ? 69.014  59.028 73.309  1.00 0.21 ? 201 SER A CA  1 
ATOM 1523 C C   . SER A 1 201 ? 68.301  58.976 71.975  1.00 0.21 ? 201 SER A C   1 
ATOM 1524 O O   . SER A 1 201 ? 68.926  58.754 70.939  1.00 0.21 ? 201 SER A O   1 
ATOM 1525 C CB  . SER A 1 201 ? 69.478  60.485 73.599  1.00 0.21 ? 201 SER A CB  1 
ATOM 1526 O OG  . SER A 1 201 ? 68.430  61.453 73.418  1.00 0.21 ? 201 SER A OG  1 
ATOM 1527 N N   . SER A 1 202 ? 66.962  59.169 71.988  1.00 0.30 ? 202 SER A N   1 
ATOM 1528 C CA  . SER A 1 202 ? 66.071  58.986 70.842  1.00 0.30 ? 202 SER A CA  1 
ATOM 1529 C C   . SER A 1 202 ? 66.182  60.055 69.759  1.00 0.30 ? 202 SER A C   1 
ATOM 1530 O O   . SER A 1 202 ? 65.892  59.806 68.593  1.00 0.30 ? 202 SER A O   1 
ATOM 1531 C CB  . SER A 1 202 ? 64.594  58.864 71.314  1.00 0.30 ? 202 SER A CB  1 
ATOM 1532 O OG  . SER A 1 202 ? 63.746  58.345 70.289  1.00 0.30 ? 202 SER A OG  1 
ATOM 1533 N N   . ARG A 1 203 ? 66.649  61.277 70.101  1.00 0.34 ? 203 ARG A N   1 
ATOM 1534 C CA  . ARG A 1 203 ? 66.820  62.346 69.123  1.00 0.34 ? 203 ARG A CA  1 
ATOM 1535 C C   . ARG A 1 203 ? 67.886  62.039 68.075  1.00 0.34 ? 203 ARG A C   1 
ATOM 1536 O O   . ARG A 1 203 ? 67.698  62.256 66.883  1.00 0.34 ? 203 ARG A O   1 
ATOM 1537 C CB  . ARG A 1 203 ? 67.130  63.700 69.811  1.00 0.34 ? 203 ARG A CB  1 
ATOM 1538 C CG  . ARG A 1 203 ? 65.980  64.226 70.693  1.00 0.34 ? 203 ARG A CG  1 
ATOM 1539 C CD  . ARG A 1 203 ? 66.173  65.697 71.086  1.00 0.34 ? 203 ARG A CD  1 
ATOM 1540 N NE  . ARG A 1 203 ? 65.025  66.063 71.977  1.00 0.34 ? 203 ARG A NE  1 
ATOM 1541 C CZ  . ARG A 1 203 ? 64.549  67.309 72.099  1.00 0.34 ? 203 ARG A CZ  1 
ATOM 1542 N NH1 . ARG A 1 203 ? 63.586  67.552 72.989  1.00 0.34 ? 203 ARG A NH1 1 
ATOM 1543 N NH2 . ARG A 1 203 ? 64.985  68.328 71.375  1.00 0.34 ? 203 ARG A NH2 1 
ATOM 1544 N N   . GLY A 1 204 ? 69.040  61.491 68.507  1.00 0.35 ? 204 GLY A N   1 
ATOM 1545 C CA  . GLY A 1 204 ? 70.016  60.897 67.602  1.00 0.35 ? 204 GLY A CA  1 
ATOM 1546 C C   . GLY A 1 204 ? 70.920  61.792 66.788  1.00 0.35 ? 204 GLY A C   1 
ATOM 1547 O O   . GLY A 1 204 ? 71.736  61.268 66.036  1.00 0.35 ? 204 GLY A O   1 
ATOM 1548 N N   . THR A 1 205 ? 70.805  63.127 66.927  1.00 0.44 ? 205 THR A N   1 
ATOM 1549 C CA  . THR A 1 205 ? 71.548  64.119 66.149  1.00 0.44 ? 205 THR A CA  1 
ATOM 1550 C C   . THR A 1 205 ? 71.604  65.385 66.985  1.00 0.44 ? 205 THR A C   1 
ATOM 1551 O O   . THR A 1 205 ? 70.710  65.626 67.790  1.00 0.44 ? 205 THR A O   1 
ATOM 1552 C CB  . THR A 1 205 ? 70.883  64.420 64.796  1.00 0.44 ? 205 THR A CB  1 
ATOM 1553 O OG1 . THR A 1 205 ? 71.154  63.383 63.868  1.00 0.44 ? 205 THR A OG1 1 
ATOM 1554 C CG2 . THR A 1 205 ? 71.374  65.691 64.084  1.00 0.44 ? 205 THR A CG2 1 
ATOM 1555 N N   . SER A 1 206 ? 72.660  66.225 66.817  1.00 0.44 ? 206 SER A N   1 
ATOM 1556 C CA  . SER A 1 206 ? 72.854  67.466 67.560  1.00 0.44 ? 206 SER A CA  1 
ATOM 1557 C C   . SER A 1 206 ? 73.571  68.478 66.674  1.00 0.44 ? 206 SER A C   1 
ATOM 1558 O O   . SER A 1 206 ? 74.298  68.033 65.784  1.00 0.44 ? 206 SER A O   1 
ATOM 1559 C CB  . SER A 1 206 ? 73.802  67.296 68.770  1.00 0.44 ? 206 SER A CB  1 
ATOM 1560 O OG  . SER A 1 206 ? 73.337  66.306 69.683  1.00 0.44 ? 206 SER A OG  1 
ATOM 1561 N N   . PRO A 1 207 ? 73.461  69.809 66.837  1.00 0.40 ? 207 PRO A N   1 
ATOM 1562 C CA  . PRO A 1 207 ? 74.042  70.781 65.906  1.00 0.40 ? 207 PRO A CA  1 
ATOM 1563 C C   . PRO A 1 207 ? 75.548  70.922 66.030  1.00 0.40 ? 207 PRO A C   1 
ATOM 1564 O O   . PRO A 1 207 ? 76.225  71.052 65.013  1.00 0.40 ? 207 PRO A O   1 
ATOM 1565 C CB  . PRO A 1 207 ? 73.343  72.112 66.261  1.00 0.40 ? 207 PRO A CB  1 
ATOM 1566 C CG  . PRO A 1 207 ? 72.895  71.943 67.715  1.00 0.40 ? 207 PRO A CG  1 
ATOM 1567 C CD  . PRO A 1 207 ? 72.570  70.453 67.802  1.00 0.40 ? 207 PRO A CD  1 
ATOM 1568 N N   . ALA A 1 208 ? 76.098  70.945 67.255  1.00 0.45 ? 208 ALA A N   1 
ATOM 1569 C CA  . ALA A 1 208 ? 77.505  71.178 67.455  1.00 0.45 ? 208 ALA A CA  1 
ATOM 1570 C C   . ALA A 1 208 ? 77.910  70.733 68.845  1.00 0.45 ? 208 ALA A C   1 
ATOM 1571 O O   . ALA A 1 208 ? 77.080  70.582 69.738  1.00 0.45 ? 208 ALA A O   1 
ATOM 1572 C CB  . ALA A 1 208 ? 77.841  72.678 67.300  1.00 0.45 ? 208 ALA A CB  1 
ATOM 1573 N N   . ARG A 1 209 ? 79.226  70.541 69.075  1.00 0.38 ? 209 ARG A N   1 
ATOM 1574 C CA  . ARG A 1 209 ? 79.791  70.321 70.397  1.00 0.38 ? 209 ARG A CA  1 
ATOM 1575 C C   . ARG A 1 209 ? 79.930  71.626 71.189  1.00 0.38 ? 209 ARG A C   1 
ATOM 1576 O O   . ARG A 1 209 ? 81.024  72.065 71.551  1.00 0.38 ? 209 ARG A O   1 
ATOM 1577 C CB  . ARG A 1 209 ? 81.149  69.580 70.287  1.00 0.38 ? 209 ARG A CB  1 
ATOM 1578 C CG  . ARG A 1 209 ? 80.976  68.080 69.971  1.00 0.38 ? 209 ARG A CG  1 
ATOM 1579 C CD  . ARG A 1 209 ? 82.287  67.293 69.863  1.00 0.38 ? 209 ARG A CD  1 
ATOM 1580 N NE  . ARG A 1 209 ? 81.927  65.837 69.850  1.00 0.38 ? 209 ARG A NE  1 
ATOM 1581 C CZ  . ARG A 1 209 ? 81.944  64.992 68.814  1.00 0.38 ? 209 ARG A CZ  1 
ATOM 1582 N NH1 . ARG A 1 209 ? 81.568  63.729 68.999  1.00 0.38 ? 209 ARG A NH1 1 
ATOM 1583 N NH2 . ARG A 1 209 ? 82.343  65.385 67.610  1.00 0.38 ? 209 ARG A NH2 1 
ATOM 1584 N N   . MET A 1 210 ? 78.787  72.264 71.497  1.00 0.33 ? 210 MET A N   1 
ATOM 1585 C CA  . MET A 1 210 ? 78.672  73.562 72.128  1.00 0.33 ? 210 MET A CA  1 
ATOM 1586 C C   . MET A 1 210 ? 77.816  73.440 73.376  1.00 0.33 ? 210 MET A C   1 
ATOM 1587 O O   . MET A 1 210 ? 76.933  72.591 73.458  1.00 0.33 ? 210 MET A O   1 
ATOM 1588 C CB  . MET A 1 210 ? 78.028  74.560 71.129  1.00 0.33 ? 210 MET A CB  1 
ATOM 1589 C CG  . MET A 1 210 ? 77.686  75.966 71.668  1.00 0.33 ? 210 MET A CG  1 
ATOM 1590 S SD  . MET A 1 210 ? 79.098  76.861 72.390  1.00 0.33 ? 210 MET A SD  1 
ATOM 1591 C CE  . MET A 1 210 ? 78.124  78.320 72.851  1.00 0.33 ? 210 MET A CE  1 
ATOM 1592 N N   . ALA A 1 211 ? 78.094  74.278 74.401  1.00 0.43 ? 211 ALA A N   1 
ATOM 1593 C CA  . ALA A 1 211 ? 77.295  74.395 75.604  1.00 0.43 ? 211 ALA A CA  1 
ATOM 1594 C C   . ALA A 1 211 ? 76.001  75.150 75.328  1.00 0.43 ? 211 ALA A C   1 
ATOM 1595 O O   . ALA A 1 211 ? 76.024  76.347 75.043  1.00 0.43 ? 211 ALA A O   1 
ATOM 1596 C CB  . ALA A 1 211 ? 78.092  75.149 76.693  1.00 0.43 ? 211 ALA A CB  1 
ATOM 1597 N N   . GLY A 1 212 ? 74.837  74.469 75.428  1.00 0.47 ? 212 GLY A N   1 
ATOM 1598 C CA  . GLY A 1 212 ? 73.545  75.022 75.032  1.00 0.47 ? 212 GLY A CA  1 
ATOM 1599 C C   . GLY A 1 212 ? 73.453  75.403 73.576  1.00 0.47 ? 212 GLY A C   1 
ATOM 1600 O O   . GLY A 1 212 ? 73.882  74.652 72.708  1.00 0.47 ? 212 GLY A O   1 
ATOM 1601 N N   . ASN A 1 213 ? 72.833  76.566 73.284  1.00 0.42 ? 213 ASN A N   1 
ATOM 1602 C CA  . ASN A 1 213 ? 72.651  77.088 71.936  1.00 0.42 ? 213 ASN A CA  1 
ATOM 1603 C C   . ASN A 1 213 ? 71.760  76.212 71.045  1.00 0.42 ? 213 ASN A C   1 
ATOM 1604 O O   . ASN A 1 213 ? 71.949  76.118 69.832  1.00 0.42 ? 213 ASN A O   1 
ATOM 1605 C CB  . ASN A 1 213 ? 74.037  77.413 71.303  1.00 0.42 ? 213 ASN A CB  1 
ATOM 1606 C CG  . ASN A 1 213 ? 73.948  78.411 70.155  1.00 0.42 ? 213 ASN A CG  1 
ATOM 1607 O OD1 . ASN A 1 213 ? 73.234  79.410 70.227  1.00 0.42 ? 213 ASN A OD1 1 
ATOM 1608 N ND2 . ASN A 1 213 ? 74.742  78.190 69.083  1.00 0.42 ? 213 ASN A ND2 1 
ATOM 1609 N N   . GLY A 1 214 ? 70.748  75.565 71.653  1.00 0.45 ? 214 GLY A N   1 
ATOM 1610 C CA  . GLY A 1 214 ? 69.749  74.775 70.957  1.00 0.45 ? 214 GLY A CA  1 
ATOM 1611 C C   . GLY A 1 214 ? 69.393  73.564 71.766  1.00 0.45 ? 214 GLY A C   1 
ATOM 1612 O O   . GLY A 1 214 ? 70.258  72.901 72.339  1.00 0.45 ? 214 GLY A O   1 
ATOM 1613 N N   . GLY A 1 215 ? 68.098  73.210 71.819  1.00 0.46 ? 215 GLY A N   1 
ATOM 1614 C CA  . GLY A 1 215 ? 67.601  72.079 72.603  1.00 0.46 ? 215 GLY A CA  1 
ATOM 1615 C C   . GLY A 1 215 ? 68.118  70.709 72.234  1.00 0.46 ? 215 GLY A C   1 
ATOM 1616 O O   . GLY A 1 215 ? 68.214  69.819 73.073  1.00 0.46 ? 215 GLY A O   1 
ATOM 1617 N N   . ASP A 1 216 ? 68.504  70.519 70.961  1.00 0.41 ? 216 ASP A N   1 
ATOM 1618 C CA  . ASP A 1 216 ? 69.107  69.301 70.454  1.00 0.41 ? 216 ASP A CA  1 
ATOM 1619 C C   . ASP A 1 216 ? 70.589  69.180 70.811  1.00 0.41 ? 216 ASP A C   1 
ATOM 1620 O O   . ASP A 1 216 ? 71.208  68.136 70.626  1.00 0.41 ? 216 ASP A O   1 
ATOM 1621 C CB  . ASP A 1 216 ? 68.916  69.214 68.919  1.00 0.41 ? 216 ASP A CB  1 
ATOM 1622 C CG  . ASP A 1 216 ? 67.456  68.969 68.569  1.00 0.41 ? 216 ASP A CG  1 
ATOM 1623 O OD1 . ASP A 1 216 ? 66.696  68.503 69.458  1.00 0.41 ? 216 ASP A OD1 1 
ATOM 1624 O OD2 . ASP A 1 216 ? 67.086  69.236 67.402  1.00 0.41 ? 216 ASP A OD2 1 
ATOM 1625 N N   . ALA A 1 217 ? 71.233  70.247 71.334  1.00 0.45 ? 217 ALA A N   1 
ATOM 1626 C CA  . ALA A 1 217 ? 72.584  70.151 71.854  1.00 0.45 ? 217 ALA A CA  1 
ATOM 1627 C C   . ALA A 1 217 ? 72.637  69.380 73.171  1.00 0.45 ? 217 ALA A C   1 
ATOM 1628 O O   . ALA A 1 217 ? 73.610  68.683 73.457  1.00 0.45 ? 217 ALA A O   1 
ATOM 1629 C CB  . ALA A 1 217 ? 73.213  71.550 71.988  1.00 0.45 ? 217 ALA A CB  1 
ATOM 1630 N N   . ALA A 1 218 ? 71.562  69.474 73.984  1.00 0.45 ? 218 ALA A N   1 
ATOM 1631 C CA  . ALA A 1 218 ? 71.336  68.643 75.146  1.00 0.45 ? 218 ALA A CA  1 
ATOM 1632 C C   . ALA A 1 218 ? 70.934  67.231 74.731  1.00 0.45 ? 218 ALA A C   1 
ATOM 1633 O O   . ALA A 1 218 ? 70.673  66.950 73.563  1.00 0.45 ? 218 ALA A O   1 
ATOM 1634 C CB  . ALA A 1 218 ? 70.243  69.265 76.042  1.00 0.45 ? 218 ALA A CB  1 
ATOM 1635 N N   . LEU A 1 219 ? 70.888  66.283 75.693  1.00 0.46 ? 219 LEU A N   1 
ATOM 1636 C CA  . LEU A 1 219 ? 70.653  64.874 75.416  1.00 0.46 ? 219 LEU A CA  1 
ATOM 1637 C C   . LEU A 1 219 ? 71.645  64.288 74.397  1.00 0.46 ? 219 LEU A C   1 
ATOM 1638 O O   . LEU A 1 219 ? 72.840  64.562 74.471  1.00 0.46 ? 219 LEU A O   1 
ATOM 1639 C CB  . LEU A 1 219 ? 69.170  64.605 75.027  1.00 0.46 ? 219 LEU A CB  1 
ATOM 1640 C CG  . LEU A 1 219 ? 68.131  65.225 75.983  1.00 0.46 ? 219 LEU A CG  1 
ATOM 1641 C CD1 . LEU A 1 219 ? 66.711  65.073 75.414  1.00 0.46 ? 219 LEU A CD1 1 
ATOM 1642 C CD2 . LEU A 1 219 ? 68.213  64.642 77.403  1.00 0.46 ? 219 LEU A CD2 1 
ATOM 1643 N N   . ALA A 1 220 ? 71.169  63.457 73.440  1.00 0.55 ? 220 ALA A N   1 
ATOM 1644 C CA  . ALA A 1 220 ? 71.793  63.196 72.150  1.00 0.55 ? 220 ALA A CA  1 
ATOM 1645 C C   . ALA A 1 220 ? 73.312  63.037 72.111  1.00 0.55 ? 220 ALA A C   1 
ATOM 1646 O O   . ALA A 1 220 ? 73.865  62.173 72.788  1.00 0.55 ? 220 ALA A O   1 
ATOM 1647 C CB  . ALA A 1 220 ? 71.237  64.229 71.153  1.00 0.55 ? 220 ALA A CB  1 
ATOM 1648 N N   . LEU A 1 221 ? 74.015  63.852 71.298  1.00 0.51 ? 221 LEU A N   1 
ATOM 1649 C CA  . LEU A 1 221 ? 75.464  63.818 71.150  1.00 0.51 ? 221 LEU A CA  1 
ATOM 1650 C C   . LEU A 1 221 ? 76.217  64.026 72.453  1.00 0.51 ? 221 LEU A C   1 
ATOM 1651 O O   . LEU A 1 221 ? 77.182  63.324 72.727  1.00 0.51 ? 221 LEU A O   1 
ATOM 1652 C CB  . LEU A 1 221 ? 75.903  64.864 70.097  1.00 0.51 ? 221 LEU A CB  1 
ATOM 1653 C CG  . LEU A 1 221 ? 77.364  64.877 69.616  1.00 0.51 ? 221 LEU A CG  1 
ATOM 1654 C CD1 . LEU A 1 221 ? 77.436  65.421 68.177  1.00 0.51 ? 221 LEU A CD1 1 
ATOM 1655 C CD2 . LEU A 1 221 ? 78.274  65.733 70.507  1.00 0.51 ? 221 LEU A CD2 1 
ATOM 1656 N N   . LEU A 1 222 ? 75.772  64.959 73.324  1.00 0.53 ? 222 LEU A N   1 
ATOM 1657 C CA  . LEU A 1 222 ? 76.385  65.216 74.615  1.00 0.53 ? 222 LEU A CA  1 
ATOM 1658 C C   . LEU A 1 222 ? 76.396  63.999 75.531  1.00 0.53 ? 222 LEU A C   1 
ATOM 1659 O O   . LEU A 1 222 ? 77.421  63.647 76.123  1.00 0.53 ? 222 LEU A O   1 
ATOM 1660 C CB  . LEU A 1 222 ? 75.579  66.355 75.294  1.00 0.53 ? 222 LEU A CB  1 
ATOM 1661 C CG  . LEU A 1 222 ? 75.791  66.564 76.806  1.00 0.53 ? 222 LEU A CG  1 
ATOM 1662 C CD1 . LEU A 1 222 ? 77.208  67.046 77.118  1.00 0.53 ? 222 LEU A CD1 1 
ATOM 1663 C CD2 . LEU A 1 222 ? 74.753  67.552 77.351  1.00 0.53 ? 222 LEU A CD2 1 
ATOM 1664 N N   . LEU A 1 223 ? 75.249  63.301 75.652  1.00 0.57 ? 223 LEU A N   1 
ATOM 1665 C CA  . LEU A 1 223 ? 75.168  62.064 76.406  1.00 0.57 ? 223 LEU A CA  1 
ATOM 1666 C C   . LEU A 1 223 ? 75.940  60.936 75.759  1.00 0.57 ? 223 LEU A C   1 
ATOM 1667 O O   . LEU A 1 223 ? 76.673  60.222 76.438  1.00 0.57 ? 223 LEU A O   1 
ATOM 1668 C CB  . LEU A 1 223 ? 73.712  61.614 76.660  1.00 0.57 ? 223 LEU A CB  1 
ATOM 1669 C CG  . LEU A 1 223 ? 72.893  62.563 77.559  1.00 0.57 ? 223 LEU A CG  1 
ATOM 1670 C CD1 . LEU A 1 223 ? 71.465  62.020 77.724  1.00 0.57 ? 223 LEU A CD1 1 
ATOM 1671 C CD2 . LEU A 1 223 ? 73.528  62.784 78.943  1.00 0.57 ? 223 LEU A CD2 1 
ATOM 1672 N N   . LEU A 1 224 ? 75.838  60.775 74.424  1.00 0.49 ? 224 LEU A N   1 
ATOM 1673 C CA  . LEU A 1 224 ? 76.586  59.764 73.700  1.00 0.49 ? 224 LEU A CA  1 
ATOM 1674 C C   . LEU A 1 224 ? 78.099  59.934 73.804  1.00 0.49 ? 224 LEU A C   1 
ATOM 1675 O O   . LEU A 1 224 ? 78.784  58.970 74.132  1.00 0.49 ? 224 LEU A O   1 
ATOM 1676 C CB  . LEU A 1 224 ? 76.148  59.700 72.216  1.00 0.49 ? 224 LEU A CB  1 
ATOM 1677 C CG  . LEU A 1 224 ? 74.743  59.099 71.979  1.00 0.49 ? 224 LEU A CG  1 
ATOM 1678 C CD1 . LEU A 1 224 ? 74.309  59.309 70.520  1.00 0.49 ? 224 LEU A CD1 1 
ATOM 1679 C CD2 . LEU A 1 224 ? 74.683  57.604 72.329  1.00 0.49 ? 224 LEU A CD2 1 
ATOM 1680 N N   . ASP A 1 225 ? 78.658  61.155 73.629  1.00 0.44 ? 225 ASP A N   1 
ATOM 1681 C CA  . ASP A 1 225 ? 80.076  61.414 73.832  1.00 0.44 ? 225 ASP A CA  1 
ATOM 1682 C C   . ASP A 1 225 ? 80.517  61.108 75.268  1.00 0.44 ? 225 ASP A C   1 
ATOM 1683 O O   . ASP A 1 225 ? 81.475  60.370 75.496  1.00 0.44 ? 225 ASP A O   1 
ATOM 1684 C CB  . ASP A 1 225 ? 80.424  62.915 73.560  1.00 0.44 ? 225 ASP A CB  1 
ATOM 1685 C CG  . ASP A 1 225 ? 80.736  63.312 72.125  1.00 0.44 ? 225 ASP A CG  1 
ATOM 1686 O OD1 . ASP A 1 225 ? 80.718  62.487 71.181  1.00 0.44 ? 225 ASP A OD1 1 
ATOM 1687 O OD2 . ASP A 1 225 ? 81.077  64.513 71.942  1.00 0.44 ? 225 ASP A OD2 1 
ATOM 1688 N N   . ARG A 1 226 ? 79.815  61.635 76.296  1.00 0.49 ? 226 ARG A N   1 
ATOM 1689 C CA  . ARG A 1 226 ? 80.221  61.446 77.680  1.00 0.49 ? 226 ARG A CA  1 
ATOM 1690 C C   . ARG A 1 226 ? 80.115  60.021 78.181  1.00 0.49 ? 226 ARG A C   1 
ATOM 1691 O O   . ARG A 1 226 ? 81.040  59.494 78.804  1.00 0.49 ? 226 ARG A O   1 
ATOM 1692 C CB  . ARG A 1 226 ? 79.415  62.374 78.627  1.00 0.49 ? 226 ARG A CB  1 
ATOM 1693 C CG  . ARG A 1 226 ? 79.756  63.868 78.450  1.00 0.49 ? 226 ARG A CG  1 
ATOM 1694 C CD  . ARG A 1 226 ? 80.710  64.500 79.483  1.00 0.49 ? 226 ARG A CD  1 
ATOM 1695 N NE  . ARG A 1 226 ? 81.941  63.674 79.721  1.00 0.49 ? 226 ARG A NE  1 
ATOM 1696 C CZ  . ARG A 1 226 ? 82.916  63.429 78.842  1.00 0.49 ? 226 ARG A CZ  1 
ATOM 1697 N NH1 . ARG A 1 226 ? 83.855  62.547 79.175  1.00 0.49 ? 226 ARG A NH1 1 
ATOM 1698 N NH2 . ARG A 1 226 ? 82.992  63.972 77.637  1.00 0.49 ? 226 ARG A NH2 1 
ATOM 1699 N N   . LEU A 1 227 ? 78.986  59.350 77.904  1.00 0.53 ? 227 LEU A N   1 
ATOM 1700 C CA  . LEU A 1 227 ? 78.768  57.981 78.300  1.00 0.53 ? 227 LEU A CA  1 
ATOM 1701 C C   . LEU A 1 227 ? 79.603  56.990 77.507  1.00 0.53 ? 227 LEU A C   1 
ATOM 1702 O O   . LEU A 1 227 ? 80.173  56.074 78.097  1.00 0.53 ? 227 LEU A O   1 
ATOM 1703 C CB  . LEU A 1 227 ? 77.262  57.637 78.278  1.00 0.53 ? 227 LEU A CB  1 
ATOM 1704 C CG  . LEU A 1 227 ? 76.402  58.512 79.226  1.00 0.53 ? 227 LEU A CG  1 
ATOM 1705 C CD1 . LEU A 1 227 ? 74.911  58.184 79.049  1.00 0.53 ? 227 LEU A CD1 1 
ATOM 1706 C CD2 . LEU A 1 227 ? 76.809  58.388 80.707  1.00 0.53 ? 227 LEU A CD2 1 
ATOM 1707 N N   . ASN A 1 228 ? 79.757  57.160 76.167  1.00 0.39 ? 228 ASN A N   1 
ATOM 1708 C CA  . ASN A 1 228 ? 80.635  56.320 75.358  1.00 0.39 ? 228 ASN A CA  1 
ATOM 1709 C C   . ASN A 1 228 ? 82.110  56.492 75.721  1.00 0.39 ? 228 ASN A C   1 
ATOM 1710 O O   . ASN A 1 228 ? 82.869  55.529 75.709  1.00 0.39 ? 228 ASN A O   1 
ATOM 1711 C CB  . ASN A 1 228 ? 80.418  56.412 73.815  1.00 0.39 ? 228 ASN A CB  1 
ATOM 1712 C CG  . ASN A 1 228 ? 79.053  55.920 73.318  1.00 0.39 ? 228 ASN A CG  1 
ATOM 1713 O OD1 . ASN A 1 228 ? 78.716  56.052 72.135  1.00 0.39 ? 228 ASN A OD1 1 
ATOM 1714 N ND2 . ASN A 1 228 ? 78.250  55.259 74.176  1.00 0.39 ? 228 ASN A ND2 1 
ATOM 1715 N N   . GLN A 1 229 ? 82.572  57.705 76.104  1.00 0.45 ? 229 GLN A N   1 
ATOM 1716 C CA  . GLN A 1 229 ? 83.917  57.883 76.641  1.00 0.45 ? 229 GLN A CA  1 
ATOM 1717 C C   . GLN A 1 229 ? 84.193  57.158 77.952  1.00 0.45 ? 229 GLN A C   1 
ATOM 1718 O O   . GLN A 1 229 ? 85.238  56.529 78.107  1.00 0.45 ? 229 GLN A O   1 
ATOM 1719 C CB  . GLN A 1 229 ? 84.274  59.376 76.818  1.00 0.45 ? 229 GLN A CB  1 
ATOM 1720 C CG  . GLN A 1 229 ? 84.685  60.022 75.481  1.00 0.45 ? 229 GLN A CG  1 
ATOM 1721 C CD  . GLN A 1 229 ? 85.138  61.471 75.639  1.00 0.45 ? 229 GLN A CD  1 
ATOM 1722 O OE1 . GLN A 1 229 ? 84.968  62.135 76.667  1.00 0.45 ? 229 GLN A OE1 1 
ATOM 1723 N NE2 . GLN A 1 229 ? 85.773  61.985 74.563  1.00 0.45 ? 229 GLN A NE2 1 
ATOM 1724 N N   . LEU A 1 230 ? 83.258  57.203 78.923  1.00 0.48 ? 230 LEU A N   1 
ATOM 1725 C CA  . LEU A 1 230 ? 83.326  56.427 80.155  1.00 0.48 ? 230 LEU A CA  1 
ATOM 1726 C C   . LEU A 1 230 ? 83.293  54.916 79.913  1.00 0.48 ? 230 LEU A C   1 
ATOM 1727 O O   . LEU A 1 230 ? 84.043  54.150 80.515  1.00 0.48 ? 230 LEU A O   1 
ATOM 1728 C CB  . LEU A 1 230 ? 82.180  56.854 81.101  1.00 0.48 ? 230 LEU A CB  1 
ATOM 1729 C CG  . LEU A 1 230 ? 82.378  58.253 81.726  1.00 0.48 ? 230 LEU A CG  1 
ATOM 1730 C CD1 . LEU A 1 230 ? 81.057  58.817 82.275  1.00 0.48 ? 230 LEU A CD1 1 
ATOM 1731 C CD2 . LEU A 1 230 ? 83.444  58.222 82.838  1.00 0.48 ? 230 LEU A CD2 1 
ATOM 1732 N N   . GLU A 1 231 ? 82.444  54.476 78.966  1.00 0.49 ? 231 GLU A N   1 
ATOM 1733 C CA  . GLU A 1 231 ? 82.295  53.113 78.486  1.00 0.49 ? 231 GLU A CA  1 
ATOM 1734 C C   . GLU A 1 231 ? 83.498  52.575 77.692  1.00 0.49 ? 231 GLU A C   1 
ATOM 1735 O O   . GLU A 1 231 ? 83.692  51.363 77.620  1.00 0.49 ? 231 GLU A O   1 
ATOM 1736 C CB  . GLU A 1 231 ? 81.010  53.103 77.616  1.00 0.49 ? 231 GLU A CB  1 
ATOM 1737 C CG  . GLU A 1 231 ? 80.740  51.885 76.697  1.00 0.49 ? 231 GLU A CG  1 
ATOM 1738 C CD  . GLU A 1 231 ? 79.508  52.031 75.822  1.00 0.49 ? 231 GLU A CD  1 
ATOM 1739 O OE1 . GLU A 1 231 ? 78.759  53.036 75.960  1.00 0.49 ? 231 GLU A OE1 1 
ATOM 1740 O OE2 . GLU A 1 231 ? 79.246  51.122 74.985  1.00 0.49 ? 231 GLU A OE2 1 
ATOM 1741 N N   . SER A 1 232 ? 84.351  53.455 77.105  1.00 0.47 ? 232 SER A N   1 
ATOM 1742 C CA  . SER A 1 232 ? 85.435  53.103 76.175  1.00 0.47 ? 232 SER A CA  1 
ATOM 1743 C C   . SER A 1 232 ? 86.430  52.105 76.742  1.00 0.47 ? 232 SER A C   1 
ATOM 1744 O O   . SER A 1 232 ? 86.755  51.095 76.121  1.00 0.47 ? 232 SER A O   1 
ATOM 1745 C CB  . SER A 1 232 ? 86.190  54.386 75.683  1.00 0.47 ? 232 SER A CB  1 
ATOM 1746 O OG  . SER A 1 232 ? 87.339  54.122 74.874  1.00 0.47 ? 232 SER A OG  1 
ATOM 1747 N N   . LYS A 1 233 ? 86.885  52.324 77.990  1.00 0.45 ? 233 LYS A N   1 
ATOM 1748 C CA  . LYS A 1 233 ? 87.631  51.309 78.705  1.00 0.45 ? 233 LYS A CA  1 
ATOM 1749 C C   . LYS A 1 233 ? 86.732  50.535 79.655  1.00 0.45 ? 233 LYS A C   1 
ATOM 1750 O O   . LYS A 1 233 ? 86.597  49.316 79.540  1.00 0.45 ? 233 LYS A O   1 
ATOM 1751 C CB  . LYS A 1 233 ? 88.837  51.932 79.447  1.00 0.45 ? 233 LYS A CB  1 
ATOM 1752 C CG  . LYS A 1 233 ? 89.899  52.474 78.472  1.00 0.45 ? 233 LYS A CG  1 
ATOM 1753 C CD  . LYS A 1 233 ? 91.183  52.981 79.154  1.00 0.45 ? 233 LYS A CD  1 
ATOM 1754 C CE  . LYS A 1 233 ? 92.002  51.856 79.797  1.00 0.45 ? 233 LYS A CE  1 
ATOM 1755 N NZ  . LYS A 1 233 ? 93.327  52.359 80.224  1.00 0.45 ? 233 LYS A NZ  1 
ATOM 1756 N N   . MET A 1 234 ? 86.095  51.224 80.630  1.00 0.43 ? 234 MET A N   1 
ATOM 1757 C CA  . MET A 1 234 ? 85.170  50.651 81.598  1.00 0.43 ? 234 MET A CA  1 
ATOM 1758 C C   . MET A 1 234 ? 85.776  49.557 82.480  1.00 0.43 ? 234 MET A C   1 
ATOM 1759 O O   . MET A 1 234 ? 85.115  48.638 82.978  1.00 0.43 ? 234 MET A O   1 
ATOM 1760 C CB  . MET A 1 234 ? 83.836  50.264 80.912  1.00 0.43 ? 234 MET A CB  1 
ATOM 1761 C CG  . MET A 1 234 ? 82.619  50.099 81.844  1.00 0.43 ? 234 MET A CG  1 
ATOM 1762 S SD  . MET A 1 234 ? 81.028  50.270 80.980  1.00 0.43 ? 234 MET A SD  1 
ATOM 1763 C CE  . MET A 1 234 ? 79.989  49.870 82.413  1.00 0.43 ? 234 MET A CE  1 
ATOM 1764 N N   . SER A 1 235 ? 87.093  49.672 82.728  1.00 0.44 ? 235 SER A N   1 
ATOM 1765 C CA  . SER A 1 235 ? 87.909  48.786 83.527  1.00 0.44 ? 235 SER A CA  1 
ATOM 1766 C C   . SER A 1 235 ? 87.673  48.968 85.021  1.00 0.44 ? 235 SER A C   1 
ATOM 1767 O O   . SER A 1 235 ? 86.958  49.863 85.468  1.00 0.44 ? 235 SER A O   1 
ATOM 1768 C CB  . SER A 1 235 ? 89.412  48.873 83.115  1.00 0.44 ? 235 SER A CB  1 
ATOM 1769 O OG  . SER A 1 235 ? 89.838  50.173 82.691  1.00 0.44 ? 235 SER A OG  1 
ATOM 1770 N N   . GLY A 1 236 ? 88.181  48.045 85.866  1.00 0.48 ? 236 GLY A N   1 
ATOM 1771 C CA  . GLY A 1 236 ? 88.000  48.169 87.304  1.00 0.48 ? 236 GLY A CA  1 
ATOM 1772 C C   . GLY A 1 236 ? 88.968  47.286 88.034  1.00 0.48 ? 236 GLY A C   1 
ATOM 1773 O O   . GLY A 1 236 ? 89.683  46.502 87.419  1.00 0.48 ? 236 GLY A O   1 
ATOM 1774 N N   . LYS A 1 237 ? 88.972  47.366 89.382  1.00 0.28 ? 237 LYS A N   1 
ATOM 1775 C CA  . LYS A 1 237 ? 89.985  46.799 90.271  1.00 0.28 ? 237 LYS A CA  1 
ATOM 1776 C C   . LYS A 1 237 ? 90.097  45.276 90.276  1.00 0.28 ? 237 LYS A C   1 
ATOM 1777 O O   . LYS A 1 237 ? 91.124  44.717 90.649  1.00 0.28 ? 237 LYS A O   1 
ATOM 1778 C CB  . LYS A 1 237 ? 89.721  47.315 91.719  1.00 0.28 ? 237 LYS A CB  1 
ATOM 1779 C CG  . LYS A 1 237 ? 90.768  46.963 92.804  1.00 0.28 ? 237 LYS A CG  1 
ATOM 1780 C CD  . LYS A 1 237 ? 92.184  47.495 92.512  1.00 0.28 ? 237 LYS A CD  1 
ATOM 1781 C CE  . LYS A 1 237 ? 93.230  47.174 93.590  1.00 0.28 ? 237 LYS A CE  1 
ATOM 1782 N NZ  . LYS A 1 237 ? 92.994  47.987 94.804  1.00 0.28 ? 237 LYS A NZ  1 
ATOM 1783 N N   . GLY A 1 238 ? 89.045  44.560 89.830  1.00 0.40 ? 238 GLY A N   1 
ATOM 1784 C CA  . GLY A 1 238 ? 89.068  43.107 89.681  1.00 0.40 ? 238 GLY A CA  1 
ATOM 1785 C C   . GLY A 1 238 ? 89.778  42.595 88.448  1.00 0.40 ? 238 GLY A C   1 
ATOM 1786 O O   . GLY A 1 238 ? 89.869  41.390 88.245  1.00 0.40 ? 238 GLY A O   1 
ATOM 1787 N N   . GLN A 1 239 ? 90.280  43.482 87.570  1.00 0.39 ? 239 GLN A N   1 
ATOM 1788 C CA  . GLN A 1 239 ? 90.969  43.091 86.356  1.00 0.39 ? 239 GLN A CA  1 
ATOM 1789 C C   . GLN A 1 239 ? 92.437  43.465 86.449  1.00 0.39 ? 239 GLN A C   1 
ATOM 1790 O O   . GLN A 1 239 ? 92.774  44.582 86.830  1.00 0.39 ? 239 GLN A O   1 
ATOM 1791 C CB  . GLN A 1 239 ? 90.386  43.842 85.130  1.00 0.39 ? 239 GLN A CB  1 
ATOM 1792 C CG  . GLN A 1 239 ? 88.900  43.510 84.856  1.00 0.39 ? 239 GLN A CG  1 
ATOM 1793 C CD  . GLN A 1 239 ? 88.238  44.511 83.913  1.00 0.39 ? 239 GLN A CD  1 
ATOM 1794 O OE1 . GLN A 1 239 ? 87.284  45.208 84.278  1.00 0.39 ? 239 GLN A OE1 1 
ATOM 1795 N NE2 . GLN A 1 239 ? 88.739  44.570 82.661  1.00 0.39 ? 239 GLN A NE2 1 
ATOM 1796 N N   . GLN A 1 240 ? 93.358  42.543 86.083  1.00 0.33 ? 240 GLN A N   1 
ATOM 1797 C CA  . GLN A 1 240 ? 94.784  42.841 86.053  1.00 0.33 ? 240 GLN A CA  1 
ATOM 1798 C C   . GLN A 1 240 ? 95.203  43.798 84.940  1.00 0.33 ? 240 GLN A C   1 
ATOM 1799 O O   . GLN A 1 240 ? 95.909  44.776 85.167  1.00 0.33 ? 240 GLN A O   1 
ATOM 1800 C CB  . GLN A 1 240 ? 95.594  41.526 85.910  1.00 0.33 ? 240 GLN A CB  1 
ATOM 1801 C CG  . GLN A 1 240 ? 97.133  41.718 85.913  1.00 0.33 ? 240 GLN A CG  1 
ATOM 1802 C CD  . GLN A 1 240 ? 97.874  40.381 85.931  1.00 0.33 ? 240 GLN A CD  1 
ATOM 1803 O OE1 . GLN A 1 240 ? 97.297  39.300 85.857  1.00 0.33 ? 240 GLN A OE1 1 
ATOM 1804 N NE2 . GLN A 1 240 ? 99.223  40.461 86.030  1.00 0.33 ? 240 GLN A NE2 1 
ATOM 1805 N N   . GLN A 1 241 ? 94.757  43.544 83.694  1.00 0.41 ? 241 GLN A N   1 
ATOM 1806 C CA  . GLN A 1 241 ? 95.060  44.399 82.569  1.00 0.41 ? 241 GLN A CA  1 
ATOM 1807 C C   . GLN A 1 241 ? 94.093  44.066 81.445  1.00 0.41 ? 241 GLN A C   1 
ATOM 1808 O O   . GLN A 1 241 ? 93.962  42.915 81.047  1.00 0.41 ? 241 GLN A O   1 
ATOM 1809 C CB  . GLN A 1 241 ? 96.534  44.253 82.098  1.00 0.41 ? 241 GLN A CB  1 
ATOM 1810 C CG  . GLN A 1 241 ? 96.897  45.096 80.852  1.00 0.41 ? 241 GLN A CG  1 
ATOM 1811 C CD  . GLN A 1 241 ? 98.393  45.392 80.706  1.00 0.41 ? 241 GLN A CD  1 
ATOM 1812 O OE1 . GLN A 1 241 ? 98.752  46.480 80.255  1.00 0.41 ? 241 GLN A OE1 1 
ATOM 1813 N NE2 . GLN A 1 241 ? 99.272  44.430 81.053  1.00 0.41 ? 241 GLN A NE2 1 
ATOM 1814 N N   . GLN A 1 242 ? 93.328  45.063 80.943  1.00 0.44 ? 242 GLN A N   1 
ATOM 1815 C CA  . GLN A 1 242 ? 92.338  44.841 79.895  1.00 0.44 ? 242 GLN A CA  1 
ATOM 1816 C C   . GLN A 1 242 ? 92.921  44.724 78.489  1.00 0.44 ? 242 GLN A C   1 
ATOM 1817 O O   . GLN A 1 242 ? 92.506  43.890 77.689  1.00 0.44 ? 242 GLN A O   1 
ATOM 1818 C CB  . GLN A 1 242 ? 91.235  45.927 79.970  1.00 0.44 ? 242 GLN A CB  1 
ATOM 1819 C CG  . GLN A 1 242 ? 90.003  45.661 79.063  1.00 0.44 ? 242 GLN A CG  1 
ATOM 1820 C CD  . GLN A 1 242 ? 88.778  46.465 79.519  1.00 0.44 ? 242 GLN A CD  1 
ATOM 1821 O OE1 . GLN A 1 242 ? 88.512  46.563 80.720  1.00 0.44 ? 242 GLN A OE1 1 
ATOM 1822 N NE2 . GLN A 1 242 ? 87.998  47.014 78.567  1.00 0.44 ? 242 GLN A NE2 1 
ATOM 1823 N N   . GLY A 1 243 ? 93.920  45.566 78.142  1.00 0.52 ? 243 GLY A N   1 
ATOM 1824 C CA  . GLY A 1 243 ? 94.721  45.368 76.932  1.00 0.52 ? 243 GLY A CA  1 
ATOM 1825 C C   . GLY A 1 243 ? 94.101  45.719 75.602  1.00 0.52 ? 243 GLY A C   1 
ATOM 1826 O O   . GLY A 1 243 ? 94.654  45.381 74.556  1.00 0.52 ? 243 GLY A O   1 
ATOM 1827 N N   . GLN A 1 244 ? 92.933  46.379 75.593  1.00 0.49 ? 244 GLN A N   1 
ATOM 1828 C CA  . GLN A 1 244 ? 92.185  46.631 74.370  1.00 0.49 ? 244 GLN A CA  1 
ATOM 1829 C C   . GLN A 1 244 ? 92.444  47.983 73.721  1.00 0.49 ? 244 GLN A C   1 
ATOM 1830 O O   . GLN A 1 244 ? 92.032  48.193 72.585  1.00 0.49 ? 244 GLN A O   1 
ATOM 1831 C CB  . GLN A 1 244 ? 90.675  46.515 74.674  1.00 0.49 ? 244 GLN A CB  1 
ATOM 1832 C CG  . GLN A 1 244 ? 90.255  45.057 74.978  1.00 0.49 ? 244 GLN A CG  1 
ATOM 1833 C CD  . GLN A 1 244 ? 88.778  44.967 75.356  1.00 0.49 ? 244 GLN A CD  1 
ATOM 1834 O OE1 . GLN A 1 244 ? 88.236  45.850 76.023  1.00 0.49 ? 244 GLN A OE1 1 
ATOM 1835 N NE2 . GLN A 1 244 ? 88.111  43.855 74.973  1.00 0.49 ? 244 GLN A NE2 1 
ATOM 1836 N N   . THR A 1 245 ? 93.140  48.907 74.424  1.00 0.44 ? 245 THR A N   1 
ATOM 1837 C CA  . THR A 1 245 ? 93.693  50.164 73.896  1.00 0.44 ? 245 THR A CA  1 
ATOM 1838 C C   . THR A 1 245 ? 92.734  51.051 73.101  1.00 0.44 ? 245 THR A C   1 
ATOM 1839 O O   . THR A 1 245 ? 93.083  51.646 72.085  1.00 0.44 ? 245 THR A O   1 
ATOM 1840 C CB  . THR A 1 245 ? 95.055  50.008 73.203  1.00 0.44 ? 245 THR A CB  1 
ATOM 1841 O OG1 . THR A 1 245 ? 95.031  49.129 72.091  1.00 0.44 ? 245 THR A OG1 1 
ATOM 1842 C CG2 . THR A 1 245 ? 96.064  49.371 74.172  1.00 0.44 ? 245 THR A CG2 1 
ATOM 1843 N N   . VAL A 1 246 ? 91.484  51.192 73.594  1.00 0.37 ? 246 VAL A N   1 
ATOM 1844 C CA  . VAL A 1 246 ? 90.400  51.894 72.926  1.00 0.37 ? 246 VAL A CA  1 
ATOM 1845 C C   . VAL A 1 246 ? 90.563  53.420 72.923  1.00 0.37 ? 246 VAL A C   1 
ATOM 1846 O O   . VAL A 1 246 ? 91.125  54.028 73.839  1.00 0.37 ? 246 VAL A O   1 
ATOM 1847 C CB  . VAL A 1 246 ? 89.035  51.462 73.470  1.00 0.37 ? 246 VAL A CB  1 
ATOM 1848 C CG1 . VAL A 1 246 ? 87.885  51.883 72.529  1.00 0.37 ? 246 VAL A CG1 1 
ATOM 1849 C CG2 . VAL A 1 246 ? 88.991  49.926 73.661  1.00 0.37 ? 246 VAL A CG2 1 
ATOM 1850 N N   . THR A 1 247 ? 90.095  54.081 71.844  1.00 0.45 ? 247 THR A N   1 
ATOM 1851 C CA  . THR A 1 247 ? 90.205  55.509 71.604  1.00 0.45 ? 247 THR A CA  1 
ATOM 1852 C C   . THR A 1 247 ? 89.294  56.368 72.473  1.00 0.45 ? 247 THR A C   1 
ATOM 1853 O O   . THR A 1 247 ? 88.283  55.938 73.026  1.00 0.45 ? 247 THR A O   1 
ATOM 1854 C CB  . THR A 1 247 ? 89.986  55.879 70.130  1.00 0.45 ? 247 THR A CB  1 
ATOM 1855 O OG1 . THR A 1 247 ? 88.721  55.450 69.644  1.00 0.45 ? 247 THR A OG1 1 
ATOM 1856 C CG2 . THR A 1 247 ? 91.037  55.187 69.246  1.00 0.45 ? 247 THR A CG2 1 
ATOM 1857 N N   . LYS A 1 248 ? 89.646  57.664 72.632  1.00 0.46 ? 248 LYS A N   1 
ATOM 1858 C CA  . LYS A 1 248 ? 88.789  58.628 73.302  1.00 0.46 ? 248 LYS A CA  1 
ATOM 1859 C C   . LYS A 1 248 ? 87.816  59.324 72.353  1.00 0.46 ? 248 LYS A C   1 
ATOM 1860 O O   . LYS A 1 248 ? 86.892  60.004 72.799  1.00 0.46 ? 248 LYS A O   1 
ATOM 1861 C CB  . LYS A 1 248 ? 89.648  59.750 73.942  1.00 0.46 ? 248 LYS A CB  1 
ATOM 1862 C CG  . LYS A 1 248 ? 90.632  59.254 75.016  1.00 0.46 ? 248 LYS A CG  1 
ATOM 1863 C CD  . LYS A 1 248 ? 91.412  60.416 75.661  1.00 0.46 ? 248 LYS A CD  1 
ATOM 1864 C CE  . LYS A 1 248 ? 92.394  60.005 76.767  1.00 0.46 ? 248 LYS A CE  1 
ATOM 1865 N NZ  . LYS A 1 248 ? 93.567  59.313 76.187  1.00 0.46 ? 248 LYS A NZ  1 
ATOM 1866 N N   . LYS A 1 249 ? 88.014  59.203 71.023  1.00 0.40 ? 249 LYS A N   1 
ATOM 1867 C CA  . LYS A 1 249 ? 87.253  59.930 70.024  1.00 0.40 ? 249 LYS A CA  1 
ATOM 1868 C C   . LYS A 1 249 ? 87.202  59.118 68.743  1.00 0.40 ? 249 LYS A C   1 
ATOM 1869 O O   . LYS A 1 249 ? 87.980  58.176 68.571  1.00 0.40 ? 249 LYS A O   1 
ATOM 1870 C CB  . LYS A 1 249 ? 87.909  61.288 69.646  1.00 0.40 ? 249 LYS A CB  1 
ATOM 1871 C CG  . LYS A 1 249 ? 87.914  62.327 70.775  1.00 0.40 ? 249 LYS A CG  1 
ATOM 1872 C CD  . LYS A 1 249 ? 88.456  63.703 70.344  1.00 0.40 ? 249 LYS A CD  1 
ATOM 1873 C CE  . LYS A 1 249 ? 89.930  63.678 69.917  1.00 0.40 ? 249 LYS A CE  1 
ATOM 1874 N NZ  . LYS A 1 249 ? 90.415  65.040 69.589  1.00 0.40 ? 249 LYS A NZ  1 
ATOM 1875 N N   . SER A 1 250 ? 86.300  59.502 67.812  1.00 0.45 ? 250 SER A N   1 
ATOM 1876 C CA  . SER A 1 250 ? 86.021  58.765 66.592  1.00 0.45 ? 250 SER A CA  1 
ATOM 1877 C C   . SER A 1 250 ? 85.974  59.684 65.403  1.00 0.45 ? 250 SER A C   1 
ATOM 1878 O O   . SER A 1 250 ? 85.411  60.772 65.483  1.00 0.45 ? 250 SER A O   1 
ATOM 1879 C CB  . SER A 1 250 ? 84.635  58.102 66.607  1.00 0.45 ? 250 SER A CB  1 
ATOM 1880 O OG  . SER A 1 250 ? 84.517  57.274 67.758  1.00 0.45 ? 250 SER A OG  1 
ATOM 1881 N N   . ALA A 1 251 ? 86.573  59.271 64.266  1.00 0.35 ? 251 ALA A N   1 
ATOM 1882 C CA  . ALA A 1 251 ? 86.466  59.964 62.993  1.00 0.35 ? 251 ALA A CA  1 
ATOM 1883 C C   . ALA A 1 251 ? 85.108  59.775 62.310  1.00 0.35 ? 251 ALA A C   1 
ATOM 1884 O O   . ALA A 1 251 ? 84.528  60.702 61.752  1.00 0.35 ? 251 ALA A O   1 
ATOM 1885 C CB  . ALA A 1 251 ? 87.607  59.493 62.062  1.00 0.35 ? 251 ALA A CB  1 
ATOM 1886 N N   . ALA A 1 252 ? 84.572  58.537 62.337  1.00 0.47 ? 252 ALA A N   1 
ATOM 1887 C CA  . ALA A 1 252 ? 83.268  58.203 61.810  1.00 0.47 ? 252 ALA A CA  1 
ATOM 1888 C C   . ALA A 1 252 ? 82.100  58.772 62.614  1.00 0.47 ? 252 ALA A C   1 
ATOM 1889 O O   . ALA A 1 252 ? 82.138  58.895 63.837  1.00 0.47 ? 252 ALA A O   1 
ATOM 1890 C CB  . ALA A 1 252 ? 83.131  56.670 61.697  1.00 0.47 ? 252 ALA A CB  1 
ATOM 1891 N N   . GLU A 1 253 ? 80.976  59.080 61.934  1.00 0.52 ? 253 GLU A N   1 
ATOM 1892 C CA  . GLU A 1 253 ? 79.828  59.714 62.555  1.00 0.52 ? 253 GLU A CA  1 
ATOM 1893 C C   . GLU A 1 253 ? 78.935  58.777 63.360  1.00 0.52 ? 253 GLU A C   1 
ATOM 1894 O O   . GLU A 1 253 ? 77.961  59.196 63.982  1.00 0.52 ? 253 GLU A O   1 
ATOM 1895 C CB  . GLU A 1 253 ? 78.958  60.387 61.480  1.00 0.52 ? 253 GLU A CB  1 
ATOM 1896 C CG  . GLU A 1 253 ? 79.664  61.574 60.796  1.00 0.52 ? 253 GLU A CG  1 
ATOM 1897 C CD  . GLU A 1 253 ? 78.611  62.429 60.097  1.00 0.52 ? 253 GLU A CD  1 
ATOM 1898 O OE1 . GLU A 1 253 ? 77.940  61.910 59.174  1.00 0.52 ? 253 GLU A OE1 1 
ATOM 1899 O OE2 . GLU A 1 253 ? 78.408  63.580 60.572  1.00 0.52 ? 253 GLU A OE2 1 
ATOM 1900 N N   . ALA A 1 254 ? 79.242  57.471 63.380  1.00 0.56 ? 254 ALA A N   1 
ATOM 1901 C CA  . ALA A 1 254 ? 78.516  56.454 64.111  1.00 0.56 ? 254 ALA A CA  1 
ATOM 1902 C C   . ALA A 1 254 ? 78.462  56.676 65.628  1.00 0.56 ? 254 ALA A C   1 
ATOM 1903 O O   . ALA A 1 254 ? 77.442  56.399 66.259  1.00 0.56 ? 254 ALA A O   1 
ATOM 1904 C CB  . ALA A 1 254 ? 79.115  55.081 63.767  1.00 0.56 ? 254 ALA A CB  1 
ATOM 1905 N N   . SER A 1 255 ? 79.532  57.226 66.248  1.00 0.54 ? 255 SER A N   1 
ATOM 1906 C CA  . SER A 1 255 ? 79.581  57.481 67.687  1.00 0.54 ? 255 SER A CA  1 
ATOM 1907 C C   . SER A 1 255 ? 78.632  58.534 68.198  1.00 0.54 ? 255 SER A C   1 
ATOM 1908 O O   . SER A 1 255 ? 78.260  58.514 69.367  1.00 0.54 ? 255 SER A O   1 
ATOM 1909 C CB  . SER A 1 255 ? 80.975  57.880 68.198  1.00 0.54 ? 255 SER A CB  1 
ATOM 1910 O OG  . SER A 1 255 ? 81.846  56.779 68.009  1.00 0.54 ? 255 SER A OG  1 
ATOM 1911 N N   . LYS A 1 256 ? 78.160  59.450 67.333  1.00 0.52 ? 256 LYS A N   1 
ATOM 1912 C CA  . LYS A 1 256 ? 77.175  60.440 67.718  1.00 0.52 ? 256 LYS A CA  1 
ATOM 1913 C C   . LYS A 1 256 ? 75.765  59.987 67.349  1.00 0.52 ? 256 LYS A C   1 
ATOM 1914 O O   . LYS A 1 256 ? 74.825  60.771 67.437  1.00 0.52 ? 256 LYS A O   1 
ATOM 1915 C CB  . LYS A 1 256 ? 77.473  61.844 67.113  1.00 0.52 ? 256 LYS A CB  1 
ATOM 1916 C CG  . LYS A 1 256 ? 77.574  61.899 65.580  1.00 0.52 ? 256 LYS A CG  1 
ATOM 1917 C CD  . LYS A 1 256 ? 77.656  63.330 65.005  1.00 0.52 ? 256 LYS A CD  1 
ATOM 1918 C CE  . LYS A 1 256 ? 77.818  63.300 63.486  1.00 0.52 ? 256 LYS A CE  1 
ATOM 1919 N NZ  . LYS A 1 256 ? 77.879  64.634 62.849  1.00 0.52 ? 256 LYS A NZ  1 
ATOM 1920 N N   . LYS A 1 257 ? 75.565  58.707 66.948  1.00 0.49 ? 257 LYS A N   1 
ATOM 1921 C CA  . LYS A 1 257 ? 74.264  58.189 66.554  1.00 0.49 ? 257 LYS A CA  1 
ATOM 1922 C C   . LYS A 1 257 ? 73.855  56.988 67.415  1.00 0.49 ? 257 LYS A C   1 
ATOM 1923 O O   . LYS A 1 257 ? 74.735  56.338 67.991  1.00 0.49 ? 257 LYS A O   1 
ATOM 1924 C CB  . LYS A 1 257 ? 74.269  57.803 65.052  1.00 0.49 ? 257 LYS A CB  1 
ATOM 1925 C CG  . LYS A 1 257 ? 74.338  59.046 64.149  1.00 0.49 ? 257 LYS A CG  1 
ATOM 1926 C CD  . LYS A 1 257 ? 74.189  58.757 62.645  1.00 0.49 ? 257 LYS A CD  1 
ATOM 1927 C CE  . LYS A 1 257 ? 75.367  57.977 62.051  1.00 0.49 ? 257 LYS A CE  1 
ATOM 1928 N NZ  . LYS A 1 257 ? 75.212  57.812 60.588  1.00 0.49 ? 257 LYS A NZ  1 
ATOM 1929 N N   . PRO A 1 258 ? 72.560  56.650 67.587  1.00 0.54 ? 258 PRO A N   1 
ATOM 1930 C CA  . PRO A 1 258 ? 72.111  55.496 68.373  1.00 0.54 ? 258 PRO A CA  1 
ATOM 1931 C C   . PRO A 1 258 ? 72.653  54.148 67.918  1.00 0.54 ? 258 PRO A C   1 
ATOM 1932 O O   . PRO A 1 258 ? 73.021  54.004 66.755  1.00 0.54 ? 258 PRO A O   1 
ATOM 1933 C CB  . PRO A 1 258 ? 70.574  55.532 68.270  1.00 0.54 ? 258 PRO A CB  1 
ATOM 1934 C CG  . PRO A 1 258 ? 70.249  56.980 67.909  1.00 0.54 ? 258 PRO A CG  1 
ATOM 1935 C CD  . PRO A 1 258 ? 71.422  57.372 67.014  1.00 0.54 ? 258 PRO A CD  1 
ATOM 1936 N N   . ARG A 1 259 ? 72.671  53.133 68.814  1.00 0.52 ? 259 ARG A N   1 
ATOM 1937 C CA  . ARG A 1 259 ? 73.320  51.843 68.611  1.00 0.52 ? 259 ARG A CA  1 
ATOM 1938 C C   . ARG A 1 259 ? 72.840  51.063 67.398  1.00 0.52 ? 259 ARG A C   1 
ATOM 1939 O O   . ARG A 1 259 ? 73.644  50.494 66.670  1.00 0.52 ? 259 ARG A O   1 
ATOM 1940 C CB  . ARG A 1 259 ? 73.168  50.929 69.856  1.00 0.52 ? 259 ARG A CB  1 
ATOM 1941 C CG  . ARG A 1 259 ? 73.653  51.527 71.201  1.00 0.52 ? 259 ARG A CG  1 
ATOM 1942 C CD  . ARG A 1 259 ? 75.147  51.887 71.283  1.00 0.52 ? 259 ARG A CD  1 
ATOM 1943 N NE  . ARG A 1 259 ? 75.371  52.445 72.665  1.00 0.52 ? 259 ARG A NE  1 
ATOM 1944 C CZ  . ARG A 1 259 ? 76.465  52.264 73.418  1.00 0.52 ? 259 ARG A CZ  1 
ATOM 1945 N NH1 . ARG A 1 259 ? 76.476  52.663 74.688  1.00 0.52 ? 259 ARG A NH1 1 
ATOM 1946 N NH2 . ARG A 1 259 ? 77.586  51.707 72.978  1.00 0.52 ? 259 ARG A NH2 1 
ATOM 1947 N N   . GLN A 1 260 ? 71.524  51.076 67.130  1.00 0.53 ? 260 GLN A N   1 
ATOM 1948 C CA  . GLN A 1 260 ? 70.885  50.396 66.025  1.00 0.53 ? 260 GLN A CA  1 
ATOM 1949 C C   . GLN A 1 260 ? 71.144  51.027 64.657  1.00 0.53 ? 260 GLN A C   1 
ATOM 1950 O O   . GLN A 1 260 ? 70.809  50.455 63.622  1.00 0.53 ? 260 GLN A O   1 
ATOM 1951 C CB  . GLN A 1 260 ? 69.354  50.290 66.275  1.00 0.53 ? 260 GLN A CB  1 
ATOM 1952 C CG  . GLN A 1 260 ? 68.523  51.609 66.250  1.00 0.53 ? 260 GLN A CG  1 
ATOM 1953 C CD  . GLN A 1 260 ? 68.518  52.412 67.559  1.00 0.53 ? 260 GLN A CD  1 
ATOM 1954 O OE1 . GLN A 1 260 ? 69.435  52.392 68.379  1.00 0.53 ? 260 GLN A OE1 1 
ATOM 1955 N NE2 . GLN A 1 260 ? 67.428  53.194 67.760  1.00 0.53 ? 260 GLN A NE2 1 
ATOM 1956 N N   . LYS A 1 261 ? 71.733  52.241 64.612  1.00 0.53 ? 261 LYS A N   1 
ATOM 1957 C CA  . LYS A 1 261 ? 72.185  52.857 63.380  1.00 0.53 ? 261 LYS A CA  1 
ATOM 1958 C C   . LYS A 1 261 ? 73.694  52.727 63.188  1.00 0.53 ? 261 LYS A C   1 
ATOM 1959 O O   . LYS A 1 261 ? 74.229  53.177 62.171  1.00 0.53 ? 261 LYS A O   1 
ATOM 1960 C CB  . LYS A 1 261 ? 71.840  54.367 63.383  1.00 0.53 ? 261 LYS A CB  1 
ATOM 1961 C CG  . LYS A 1 261 ? 70.352  54.658 63.114  1.00 0.53 ? 261 LYS A CG  1 
ATOM 1962 C CD  . LYS A 1 261 ? 70.064  56.167 62.981  1.00 0.53 ? 261 LYS A CD  1 
ATOM 1963 C CE  . LYS A 1 261 ? 68.724  56.518 62.317  1.00 0.53 ? 261 LYS A CE  1 
ATOM 1964 N NZ  . LYS A 1 261 ? 67.588  56.194 63.208  1.00 0.53 ? 261 LYS A NZ  1 
ATOM 1965 N N   . ARG A 1 262 ? 74.427  52.125 64.145  1.00 0.53 ? 262 ARG A N   1 
ATOM 1966 C CA  . ARG A 1 262 ? 75.851  51.860 64.019  1.00 0.53 ? 262 ARG A CA  1 
ATOM 1967 C C   . ARG A 1 262 ? 76.130  50.508 63.375  1.00 0.53 ? 262 ARG A C   1 
ATOM 1968 O O   . ARG A 1 262 ? 75.375  49.561 63.563  1.00 0.53 ? 262 ARG A O   1 
ATOM 1969 C CB  . ARG A 1 262 ? 76.558  51.813 65.400  1.00 0.53 ? 262 ARG A CB  1 
ATOM 1970 C CG  . ARG A 1 262 ? 76.364  53.071 66.266  1.00 0.53 ? 262 ARG A CG  1 
ATOM 1971 C CD  . ARG A 1 262 ? 77.135  53.029 67.593  1.00 0.53 ? 262 ARG A CD  1 
ATOM 1972 N NE  . ARG A 1 262 ? 76.694  54.218 68.379  1.00 0.53 ? 262 ARG A NE  1 
ATOM 1973 C CZ  . ARG A 1 262 ? 77.315  54.710 69.455  1.00 0.53 ? 262 ARG A CZ  1 
ATOM 1974 N NH1 . ARG A 1 262 ? 76.924  55.889 69.927  1.00 0.53 ? 262 ARG A NH1 1 
ATOM 1975 N NH2 . ARG A 1 262 ? 78.317  54.107 70.082  1.00 0.53 ? 262 ARG A NH2 1 
ATOM 1976 N N   . THR A 1 263 ? 77.269  50.382 62.655  1.00 0.56 ? 263 THR A N   1 
ATOM 1977 C CA  . THR A 1 263 ? 77.756  49.114 62.107  1.00 0.56 ? 263 THR A CA  1 
ATOM 1978 C C   . THR A 1 263 ? 79.266  49.225 62.070  1.00 0.56 ? 263 THR A C   1 
ATOM 1979 O O   . THR A 1 263 ? 79.804  50.185 61.523  1.00 0.56 ? 263 THR A O   1 
ATOM 1980 C CB  . THR A 1 263 ? 77.235  48.788 60.704  1.00 0.56 ? 263 THR A CB  1 
ATOM 1981 O OG1 . THR A 1 263 ? 75.877  48.394 60.786  1.00 0.56 ? 263 THR A OG1 1 
ATOM 1982 C CG2 . THR A 1 263 ? 77.952  47.606 60.028  1.00 0.56 ? 263 THR A CG2 1 
ATOM 1983 N N   . ALA A 1 264 ? 80.003  48.278 62.693  1.00 0.60 ? 264 ALA A N   1 
ATOM 1984 C CA  . ALA A 1 264 ? 81.459  48.290 62.728  1.00 0.60 ? 264 ALA A CA  1 
ATOM 1985 C C   . ALA A 1 264 ? 82.141  47.872 61.420  1.00 0.60 ? 264 ALA A C   1 
ATOM 1986 O O   . ALA A 1 264 ? 81.625  47.069 60.642  1.00 0.60 ? 264 ALA A O   1 
ATOM 1987 C CB  . ALA A 1 264 ? 81.985  47.455 63.912  1.00 0.60 ? 264 ALA A CB  1 
ATOM 1988 N N   . THR A 1 265 ? 83.343  48.422 61.151  1.00 0.56 ? 265 THR A N   1 
ATOM 1989 C CA  . THR A 1 265 ? 84.101  48.229 59.916  1.00 0.56 ? 265 THR A CA  1 
ATOM 1990 C C   . THR A 1 265 ? 85.577  48.306 60.260  1.00 0.56 ? 265 THR A C   1 
ATOM 1991 O O   . THR A 1 265 ? 85.949  48.623 61.386  1.00 0.56 ? 265 THR A O   1 
ATOM 1992 C CB  . THR A 1 265 ? 83.818  49.263 58.801  1.00 0.56 ? 265 THR A CB  1 
ATOM 1993 O OG1 . THR A 1 265 ? 84.229  50.583 59.134  1.00 0.56 ? 265 THR A OG1 1 
ATOM 1994 C CG2 . THR A 1 265 ? 82.319  49.342 58.488  1.00 0.56 ? 265 THR A CG2 1 
ATOM 1995 N N   . LYS A 1 266 ? 86.489  48.052 59.297  1.00 0.51 ? 266 LYS A N   1 
ATOM 1996 C CA  . LYS A 1 266 ? 87.920  48.297 59.458  1.00 0.51 ? 266 LYS A CA  1 
ATOM 1997 C C   . LYS A 1 266 ? 88.271  49.764 59.758  1.00 0.51 ? 266 LYS A C   1 
ATOM 1998 O O   . LYS A 1 266 ? 89.261  50.061 60.425  1.00 0.51 ? 266 LYS A O   1 
ATOM 1999 C CB  . LYS A 1 266 ? 88.685  47.811 58.196  1.00 0.51 ? 266 LYS A CB  1 
ATOM 2000 C CG  . LYS A 1 266 ? 90.223  47.876 58.300  1.00 0.51 ? 266 LYS A CG  1 
ATOM 2001 C CD  . LYS A 1 266 ? 90.924  47.218 57.095  1.00 0.51 ? 266 LYS A CD  1 
ATOM 2002 C CE  . LYS A 1 266 ? 92.452  47.129 57.201  1.00 0.51 ? 266 LYS A CE  1 
ATOM 2003 N NZ  . LYS A 1 266 ? 93.043  48.481 57.102  1.00 0.51 ? 266 LYS A NZ  1 
ATOM 2004 N N   . ALA A 1 267 ? 87.450  50.715 59.264  1.00 0.52 ? 267 ALA A N   1 
ATOM 2005 C CA  . ALA A 1 267 ? 87.563  52.134 59.537  1.00 0.52 ? 267 ALA A CA  1 
ATOM 2006 C C   . ALA A 1 267 ? 86.901  52.566 60.856  1.00 0.52 ? 267 ALA A C   1 
ATOM 2007 O O   . ALA A 1 267 ? 87.157  53.658 61.360  1.00 0.52 ? 267 ALA A O   1 
ATOM 2008 C CB  . ALA A 1 267 ? 86.908  52.888 58.359  1.00 0.52 ? 267 ALA A CB  1 
ATOM 2009 N N   . TYR A 1 268 ? 86.043  51.720 61.464  1.00 0.46 ? 268 TYR A N   1 
ATOM 2010 C CA  . TYR A 1 268 ? 85.349  52.043 62.695  1.00 0.46 ? 268 TYR A CA  1 
ATOM 2011 C C   . TYR A 1 268 ? 85.184  50.758 63.499  1.00 0.46 ? 268 TYR A C   1 
ATOM 2012 O O   . TYR A 1 268 ? 84.254  49.979 63.299  1.00 0.46 ? 268 TYR A O   1 
ATOM 2013 C CB  . TYR A 1 268 ? 83.983  52.715 62.378  1.00 0.46 ? 268 TYR A CB  1 
ATOM 2014 C CG  . TYR A 1 268 ? 83.197  53.070 63.609  1.00 0.46 ? 268 TYR A CG  1 
ATOM 2015 C CD1 . TYR A 1 268 ? 83.611  54.105 64.461  1.00 0.46 ? 268 TYR A CD1 1 
ATOM 2016 C CD2 . TYR A 1 268 ? 82.025  52.361 63.917  1.00 0.46 ? 268 TYR A CD2 1 
ATOM 2017 C CE1 . TYR A 1 268 ? 82.844  54.447 65.583  1.00 0.46 ? 268 TYR A CE1 1 
ATOM 2018 C CE2 . TYR A 1 268 ? 81.274  52.684 65.052  1.00 0.46 ? 268 TYR A CE2 1 
ATOM 2019 C CZ  . TYR A 1 268 ? 81.677  53.740 65.870  1.00 0.46 ? 268 TYR A CZ  1 
ATOM 2020 O OH  . TYR A 1 268 ? 80.871  54.115 66.952  1.00 0.46 ? 268 TYR A OH  1 
ATOM 2021 N N   . ASN A 1 269 ? 86.128  50.483 64.422  1.00 0.57 ? 269 ASN A N   1 
ATOM 2022 C CA  . ASN A 1 269 ? 86.193  49.241 65.178  1.00 0.57 ? 269 ASN A CA  1 
ATOM 2023 C C   . ASN A 1 269 ? 85.002  48.948 66.105  1.00 0.57 ? 269 ASN A C   1 
ATOM 2024 O O   . ASN A 1 269 ? 84.318  49.848 66.588  1.00 0.57 ? 269 ASN A O   1 
ATOM 2025 C CB  . ASN A 1 269 ? 87.530  49.124 65.962  1.00 0.57 ? 269 ASN A CB  1 
ATOM 2026 C CG  . ASN A 1 269 ? 88.680  48.785 65.016  1.00 0.57 ? 269 ASN A CG  1 
ATOM 2027 O OD1 . ASN A 1 269 ? 88.702  47.720 64.399  1.00 0.57 ? 269 ASN A OD1 1 
ATOM 2028 N ND2 . ASN A 1 269 ? 89.695  49.668 64.902  1.00 0.57 ? 269 ASN A ND2 1 
ATOM 2029 N N   . VAL A 1 270 ? 84.750  47.645 66.405  1.00 0.62 ? 270 VAL A N   1 
ATOM 2030 C CA  . VAL A 1 270 ? 83.701  47.158 67.313  1.00 0.62 ? 270 VAL A CA  1 
ATOM 2031 C C   . VAL A 1 270 ? 83.798  47.785 68.701  1.00 0.62 ? 270 VAL A C   1 
ATOM 2032 O O   . VAL A 1 270 ? 82.794  48.133 69.315  1.00 0.62 ? 270 VAL A O   1 
ATOM 2033 C CB  . VAL A 1 270 ? 83.743  45.627 67.427  1.00 0.62 ? 270 VAL A CB  1 
ATOM 2034 C CG1 . VAL A 1 270 ? 82.745  45.085 68.476  1.00 0.62 ? 270 VAL A CG1 1 
ATOM 2035 C CG2 . VAL A 1 270 ? 83.419  44.990 66.061  1.00 0.62 ? 270 VAL A CG2 1 
ATOM 2036 N N   . THR A 1 271 ? 85.041  48.008 69.172  1.00 0.54 ? 271 THR A N   1 
ATOM 2037 C CA  . THR A 1 271 ? 85.409  48.706 70.397  1.00 0.54 ? 271 THR A CA  1 
ATOM 2038 C C   . THR A 1 271 ? 84.924  50.148 70.483  1.00 0.54 ? 271 THR A C   1 
ATOM 2039 O O   . THR A 1 271 ? 84.699  50.671 71.568  1.00 0.54 ? 271 THR A O   1 
ATOM 2040 C CB  . THR A 1 271 ? 86.923  48.713 70.607  1.00 0.54 ? 271 THR A CB  1 
ATOM 2041 O OG1 . THR A 1 271 ? 87.632  49.209 69.476  1.00 0.54 ? 271 THR A OG1 1 
ATOM 2042 C CG2 . THR A 1 271 ? 87.438  47.283 70.814  1.00 0.54 ? 271 THR A CG2 1 
ATOM 2043 N N   . GLN A 1 272 ? 84.765  50.851 69.340  1.00 0.53 ? 272 GLN A N   1 
ATOM 2044 C CA  . GLN A 1 272 ? 84.209  52.191 69.315  1.00 0.53 ? 272 GLN A CA  1 
ATOM 2045 C C   . GLN A 1 272 ? 82.685  52.172 69.293  1.00 0.53 ? 272 GLN A C   1 
ATOM 2046 O O   . GLN A 1 272 ? 82.011  53.027 69.866  1.00 0.53 ? 272 GLN A O   1 
ATOM 2047 C CB  . GLN A 1 272 ? 84.750  52.981 68.103  1.00 0.53 ? 272 GLN A CB  1 
ATOM 2048 C CG  . GLN A 1 272 ? 86.293  53.099 68.104  1.00 0.53 ? 272 GLN A CG  1 
ATOM 2049 C CD  . GLN A 1 272 ? 86.784  54.078 67.036  1.00 0.53 ? 272 GLN A CD  1 
ATOM 2050 O OE1 . GLN A 1 272 ? 86.091  54.995 66.591  1.00 0.53 ? 272 GLN A OE1 1 
ATOM 2051 N NE2 . GLN A 1 272 ? 88.047  53.886 66.588  1.00 0.53 ? 272 GLN A NE2 1 
ATOM 2052 N N   . ALA A 1 273 ? 82.083  51.159 68.635  1.00 0.57 ? 273 ALA A N   1 
ATOM 2053 C CA  . ALA A 1 273 ? 80.652  50.945 68.651  1.00 0.57 ? 273 ALA A CA  1 
ATOM 2054 C C   . ALA A 1 273 ? 80.087  50.600 70.031  1.00 0.57 ? 273 ALA A C   1 
ATOM 2055 O O   . ALA A 1 273 ? 79.026  51.109 70.418  1.00 0.57 ? 273 ALA A O   1 
ATOM 2056 C CB  . ALA A 1 273 ? 80.269  49.850 67.632  1.00 0.57 ? 273 ALA A CB  1 
ATOM 2057 N N   . PHE A 1 274 ? 80.806  49.740 70.779  1.00 0.50 ? 274 PHE A N   1 
ATOM 2058 C CA  . PHE A 1 274 ? 80.416  49.221 72.071  1.00 0.50 ? 274 PHE A CA  1 
ATOM 2059 C C   . PHE A 1 274 ? 81.640  49.070 72.959  1.00 0.50 ? 274 PHE A C   1 
ATOM 2060 O O   . PHE A 1 274 ? 82.675  48.582 72.513  1.00 0.50 ? 274 PHE A O   1 
ATOM 2061 C CB  . PHE A 1 274 ? 79.839  47.784 71.948  1.00 0.50 ? 274 PHE A CB  1 
ATOM 2062 C CG  . PHE A 1 274 ? 78.691  47.695 70.988  1.00 0.50 ? 274 PHE A CG  1 
ATOM 2063 C CD1 . PHE A 1 274 ? 77.490  48.371 71.243  1.00 0.50 ? 274 PHE A CD1 1 
ATOM 2064 C CD2 . PHE A 1 274 ? 78.789  46.899 69.836  1.00 0.50 ? 274 PHE A CD2 1 
ATOM 2065 C CE1 . PHE A 1 274 ? 76.396  48.233 70.379  1.00 0.50 ? 274 PHE A CE1 1 
ATOM 2066 C CE2 . PHE A 1 274 ? 77.705  46.773 68.959  1.00 0.50 ? 274 PHE A CE2 1 
ATOM 2067 C CZ  . PHE A 1 274 ? 76.504  47.437 69.235  1.00 0.50 ? 274 PHE A CZ  1 
ATOM 2068 N N   . GLY A 1 275 ? 81.534  49.448 74.251  1.00 0.56 ? 275 GLY A N   1 
ATOM 2069 C CA  . GLY A 1 275 ? 82.590  49.219 75.236  1.00 0.56 ? 275 GLY A CA  1 
ATOM 2070 C C   . GLY A 1 275 ? 82.719  47.804 75.736  1.00 0.56 ? 275 GLY A C   1 
ATOM 2071 O O   . GLY A 1 275 ? 82.390  46.823 75.069  1.00 0.56 ? 275 GLY A O   1 
ATOM 2072 N N   . ARG A 1 276 ? 83.231  47.656 76.977  1.00 0.45 ? 276 ARG A N   1 
ATOM 2073 C CA  . ARG A 1 276 ? 83.393  46.359 77.613  1.00 0.45 ? 276 ARG A CA  1 
ATOM 2074 C C   . ARG A 1 276 ? 82.084  45.574 77.756  1.00 0.45 ? 276 ARG A C   1 
ATOM 2075 O O   . ARG A 1 276 ? 81.126  46.040 78.363  1.00 0.45 ? 276 ARG A O   1 
ATOM 2076 C CB  . ARG A 1 276 ? 84.075  46.492 79.002  1.00 0.45 ? 276 ARG A CB  1 
ATOM 2077 C CG  . ARG A 1 276 ? 84.812  45.218 79.469  1.00 0.45 ? 276 ARG A CG  1 
ATOM 2078 C CD  . ARG A 1 276 ? 85.455  45.331 80.862  1.00 0.45 ? 276 ARG A CD  1 
ATOM 2079 N NE  . ARG A 1 276 ? 84.396  45.080 81.906  1.00 0.45 ? 276 ARG A NE  1 
ATOM 2080 C CZ  . ARG A 1 276 ? 84.152  43.913 82.519  1.00 0.45 ? 276 ARG A CZ  1 
ATOM 2081 N NH1 . ARG A 1 276 ? 83.158  43.822 83.405  1.00 0.45 ? 276 ARG A NH1 1 
ATOM 2082 N NH2 . ARG A 1 276 ? 84.898  42.835 82.292  1.00 0.45 ? 276 ARG A NH2 1 
ATOM 2083 N N   . ARG A 1 277 ? 82.013  44.362 77.170  1.00 0.50 ? 277 ARG A N   1 
ATOM 2084 C CA  . ARG A 1 277 ? 80.783  43.592 77.063  1.00 0.50 ? 277 ARG A CA  1 
ATOM 2085 C C   . ARG A 1 277 ? 80.493  42.674 78.251  1.00 0.50 ? 277 ARG A C   1 
ATOM 2086 O O   . ARG A 1 277 ? 81.336  42.439 79.120  1.00 0.50 ? 277 ARG A O   1 
ATOM 2087 C CB  . ARG A 1 277 ? 80.815  42.790 75.735  1.00 0.50 ? 277 ARG A CB  1 
ATOM 2088 C CG  . ARG A 1 277 ? 80.455  43.665 74.514  1.00 0.50 ? 277 ARG A CG  1 
ATOM 2089 C CD  . ARG A 1 277 ? 80.983  43.177 73.159  1.00 0.50 ? 277 ARG A CD  1 
ATOM 2090 N NE  . ARG A 1 277 ? 80.439  41.798 72.912  1.00 0.50 ? 277 ARG A NE  1 
ATOM 2091 C CZ  . ARG A 1 277 ? 81.167  40.735 72.553  1.00 0.50 ? 277 ARG A CZ  1 
ATOM 2092 N NH1 . ARG A 1 277 ? 80.604  39.559 72.279  1.00 0.50 ? 277 ARG A NH1 1 
ATOM 2093 N NH2 . ARG A 1 277 ? 82.487  40.802 72.403  1.00 0.50 ? 277 ARG A NH2 1 
ATOM 2094 N N   . GLY A 1 278 ? 79.260  42.122 78.318  1.00 0.56 ? 278 GLY A N   1 
ATOM 2095 C CA  . GLY A 1 278 ? 78.820  41.333 79.456  1.00 0.56 ? 278 GLY A CA  1 
ATOM 2096 C C   . GLY A 1 278 ? 77.369  40.966 79.289  1.00 0.56 ? 278 GLY A C   1 
ATOM 2097 O O   . GLY A 1 278 ? 76.844  41.089 78.183  1.00 0.56 ? 278 GLY A O   1 
ATOM 2098 N N   . PRO A 1 279 ? 76.671  40.521 80.335  1.00 0.51 ? 279 PRO A N   1 
ATOM 2099 C CA  . PRO A 1 279 ? 75.248  40.195 80.279  1.00 0.51 ? 279 PRO A CA  1 
ATOM 2100 C C   . PRO A 1 279 ? 74.398  41.465 80.310  1.00 0.51 ? 279 PRO A C   1 
ATOM 2101 O O   . PRO A 1 279 ? 73.668  41.699 81.272  1.00 0.51 ? 279 PRO A O   1 
ATOM 2102 C CB  . PRO A 1 279 ? 75.050  39.338 81.548  1.00 0.51 ? 279 PRO A CB  1 
ATOM 2103 C CG  . PRO A 1 279 ? 76.077  39.882 82.544  1.00 0.51 ? 279 PRO A CG  1 
ATOM 2104 C CD  . PRO A 1 279 ? 77.252  40.275 81.654  1.00 0.51 ? 279 PRO A CD  1 
ATOM 2105 N N   . GLU A 1 280 ? 74.475  42.293 79.253  1.00 0.53 ? 280 GLU A N   1 
ATOM 2106 C CA  . GLU A 1 280 ? 73.960  43.645 79.235  1.00 0.53 ? 280 GLU A CA  1 
ATOM 2107 C C   . GLU A 1 280 ? 73.276  43.900 77.904  1.00 0.53 ? 280 GLU A C   1 
ATOM 2108 O O   . GLU A 1 280 ? 73.721  43.438 76.860  1.00 0.53 ? 280 GLU A O   1 
ATOM 2109 C CB  . GLU A 1 280 ? 75.106  44.671 79.455  1.00 0.53 ? 280 GLU A CB  1 
ATOM 2110 C CG  . GLU A 1 280 ? 75.806  44.493 80.830  1.00 0.53 ? 280 GLU A CG  1 
ATOM 2111 C CD  . GLU A 1 280 ? 76.777  45.609 81.224  1.00 0.53 ? 280 GLU A CD  1 
ATOM 2112 O OE1 . GLU A 1 280 ? 76.313  46.774 81.337  1.00 0.53 ? 280 GLU A OE1 1 
ATOM 2113 O OE2 . GLU A 1 280 ? 77.968  45.281 81.474  1.00 0.53 ? 280 GLU A OE2 1 
ATOM 2114 N N   . GLN A 1 281 ? 72.120  44.601 77.916  1.00 0.54 ? 281 GLN A N   1 
ATOM 2115 C CA  . GLN A 1 281 ? 71.277  44.741 76.738  1.00 0.54 ? 281 GLN A CA  1 
ATOM 2116 C C   . GLN A 1 281 ? 71.700  45.799 75.727  1.00 0.54 ? 281 GLN A C   1 
ATOM 2117 O O   . GLN A 1 281 ? 71.410  45.682 74.543  1.00 0.54 ? 281 GLN A O   1 
ATOM 2118 C CB  . GLN A 1 281 ? 69.823  45.017 77.188  1.00 0.54 ? 281 GLN A CB  1 
ATOM 2119 C CG  . GLN A 1 281 ? 68.758  44.969 76.062  1.00 0.54 ? 281 GLN A CG  1 
ATOM 2120 C CD  . GLN A 1 281 ? 67.361  44.970 76.677  1.00 0.54 ? 281 GLN A CD  1 
ATOM 2121 O OE1 . GLN A 1 281 ? 67.195  45.211 77.871  1.00 0.54 ? 281 GLN A OE1 1 
ATOM 2122 N NE2 . GLN A 1 281 ? 66.321  44.652 75.876  1.00 0.54 ? 281 GLN A NE2 1 
ATOM 2123 N N   . THR A 1 282 ? 72.373  46.885 76.156  1.00 0.56 ? 282 THR A N   1 
ATOM 2124 C CA  . THR A 1 282 ? 72.742  47.999 75.279  1.00 0.56 ? 282 THR A CA  1 
ATOM 2125 C C   . THR A 1 282 ? 73.874  47.697 74.316  1.00 0.56 ? 282 THR A C   1 
ATOM 2126 O O   . THR A 1 282 ? 73.875  48.120 73.156  1.00 0.56 ? 282 THR A O   1 
ATOM 2127 C CB  . THR A 1 282 ? 73.089  49.240 76.084  1.00 0.56 ? 282 THR A CB  1 
ATOM 2128 O OG1 . THR A 1 282 ? 71.961  49.638 76.848  1.00 0.56 ? 282 THR A OG1 1 
ATOM 2129 C CG2 . THR A 1 282 ? 73.459  50.457 75.223  1.00 0.56 ? 282 THR A CG2 1 
ATOM 2130 N N   . GLN A 1 283 ? 74.906  46.982 74.791  1.00 0.53 ? 283 GLN A N   1 
ATOM 2131 C CA  . GLN A 1 283 ? 76.062  46.587 74.022  1.00 0.53 ? 283 GLN A CA  1 
ATOM 2132 C C   . GLN A 1 283 ? 75.790  45.347 73.188  1.00 0.53 ? 283 GLN A C   1 
ATOM 2133 O O   . GLN A 1 283 ? 75.036  44.452 73.553  1.00 0.53 ? 283 GLN A O   1 
ATOM 2134 C CB  . GLN A 1 283 ? 77.311  46.365 74.923  1.00 0.53 ? 283 GLN A CB  1 
ATOM 2135 C CG  . GLN A 1 283 ? 77.934  47.660 75.517  1.00 0.53 ? 283 GLN A CG  1 
ATOM 2136 C CD  . GLN A 1 283 ? 77.014  48.381 76.510  1.00 0.53 ? 283 GLN A CD  1 
ATOM 2137 O OE1 . GLN A 1 283 ? 76.171  47.778 77.179  1.00 0.53 ? 283 GLN A OE1 1 
ATOM 2138 N NE2 . GLN A 1 283 ? 77.148  49.723 76.582  1.00 0.53 ? 283 GLN A NE2 1 
ATOM 2139 N N   . GLY A 1 284 ? 76.401  45.266 71.987  1.00 0.59 ? 284 GLY A N   1 
ATOM 2140 C CA  . GLY A 1 284 ? 76.216  44.129 71.098  1.00 0.59 ? 284 GLY A CA  1 
ATOM 2141 C C   . GLY A 1 284 ? 76.662  42.782 71.617  1.00 0.59 ? 284 GLY A C   1 
ATOM 2142 O O   . GLY A 1 284 ? 77.717  42.618 72.233  1.00 0.59 ? 284 GLY A O   1 
ATOM 2143 N N   . ASN A 1 285 ? 75.889  41.733 71.277  1.00 0.58 ? 285 ASN A N   1 
ATOM 2144 C CA  . ASN A 1 285 ? 76.153  40.379 71.732  1.00 0.58 ? 285 ASN A CA  1 
ATOM 2145 C C   . ASN A 1 285 ? 77.361  39.738 71.049  1.00 0.58 ? 285 ASN A C   1 
ATOM 2146 O O   . ASN A 1 285 ? 77.927  38.760 71.535  1.00 0.58 ? 285 ASN A O   1 
ATOM 2147 C CB  . ASN A 1 285 ? 74.935  39.463 71.452  1.00 0.58 ? 285 ASN A CB  1 
ATOM 2148 C CG  . ASN A 1 285 ? 73.749  39.889 72.303  1.00 0.58 ? 285 ASN A CG  1 
ATOM 2149 O OD1 . ASN A 1 285 ? 73.828  39.884 73.527  1.00 0.58 ? 285 ASN A OD1 1 
ATOM 2150 N ND2 . ASN A 1 285 ? 72.603  40.229 71.671  1.00 0.58 ? 285 ASN A ND2 1 
ATOM 2151 N N   . PHE A 1 286 ? 77.803  40.286 69.903  1.00 0.58 ? 286 PHE A N   1 
ATOM 2152 C CA  . PHE A 1 286 ? 78.559  39.559 68.901  1.00 0.58 ? 286 PHE A CA  1 
ATOM 2153 C C   . PHE A 1 286 ? 80.024  39.997 68.817  1.00 0.58 ? 286 PHE A C   1 
ATOM 2154 O O   . PHE A 1 286 ? 80.330  41.184 68.733  1.00 0.58 ? 286 PHE A O   1 
ATOM 2155 C CB  . PHE A 1 286 ? 77.890  39.742 67.503  1.00 0.58 ? 286 PHE A CB  1 
ATOM 2156 C CG  . PHE A 1 286 ? 76.385  39.650 67.582  1.00 0.58 ? 286 PHE A CG  1 
ATOM 2157 C CD1 . PHE A 1 286 ? 75.750  38.419 67.811  1.00 0.58 ? 286 PHE A CD1 1 
ATOM 2158 C CD2 . PHE A 1 286 ? 75.589  40.801 67.440  1.00 0.58 ? 286 PHE A CD2 1 
ATOM 2159 C CE1 . PHE A 1 286 ? 74.352  38.338 67.900  1.00 0.58 ? 286 PHE A CE1 1 
ATOM 2160 C CE2 . PHE A 1 286 ? 74.195  40.725 67.533  1.00 0.58 ? 286 PHE A CE2 1 
ATOM 2161 C CZ  . PHE A 1 286 ? 73.575  39.494 67.763  1.00 0.58 ? 286 PHE A CZ  1 
ATOM 2162 N N   . GLY A 1 287 ? 80.981  39.035 68.839  1.00 0.66 ? 287 GLY A N   1 
ATOM 2163 C CA  . GLY A 1 287 ? 82.414  39.302 68.659  1.00 0.66 ? 287 GLY A CA  1 
ATOM 2164 C C   . GLY A 1 287 ? 83.260  38.714 69.756  1.00 0.66 ? 287 GLY A C   1 
ATOM 2165 O O   . GLY A 1 287 ? 82.781  38.497 70.868  1.00 0.66 ? 287 GLY A O   1 
ATOM 2166 N N   . ASP A 1 288 ? 84.558  38.476 69.485  1.00 0.69 ? 288 ASP A N   1 
ATOM 2167 C CA  . ASP A 1 288 ? 85.457  37.810 70.397  1.00 0.69 ? 288 ASP A CA  1 
ATOM 2168 C C   . ASP A 1 288 ? 86.828  38.502 70.348  1.00 0.69 ? 288 ASP A C   1 
ATOM 2169 O O   . ASP A 1 288 ? 87.092  39.291 69.442  1.00 0.69 ? 288 ASP A O   1 
ATOM 2170 C CB  . ASP A 1 288 ? 85.546  36.309 70.025  1.00 0.69 ? 288 ASP A CB  1 
ATOM 2171 C CG  . ASP A 1 288 ? 86.084  35.518 71.192  1.00 0.69 ? 288 ASP A CG  1 
ATOM 2172 O OD1 . ASP A 1 288 ? 86.254  36.108 72.289  1.00 0.69 ? 288 ASP A OD1 1 
ATOM 2173 O OD2 . ASP A 1 288 ? 86.290  34.296 71.022  1.00 0.69 ? 288 ASP A OD2 1 
ATOM 2174 N N   . GLN A 1 289 ? 87.723  38.230 71.327  1.00 0.69 ? 289 GLN A N   1 
ATOM 2175 C CA  . GLN A 1 289 ? 89.012  38.888 71.541  1.00 0.69 ? 289 GLN A CA  1 
ATOM 2176 C C   . GLN A 1 289 ? 90.007  38.727 70.394  1.00 0.69 ? 289 GLN A C   1 
ATOM 2177 O O   . GLN A 1 289 ? 90.872  39.578 70.190  1.00 0.69 ? 289 GLN A O   1 
ATOM 2178 C CB  . GLN A 1 289 ? 89.676  38.458 72.878  1.00 0.69 ? 289 GLN A CB  1 
ATOM 2179 C CG  . GLN A 1 289 ? 88.975  39.012 74.147  1.00 0.69 ? 289 GLN A CG  1 
ATOM 2180 C CD  . GLN A 1 289 ? 89.372  40.453 74.494  1.00 0.69 ? 289 GLN A CD  1 
ATOM 2181 O OE1 . GLN A 1 289 ? 89.100  41.420 73.779  1.00 0.69 ? 289 GLN A OE1 1 
ATOM 2182 N NE2 . GLN A 1 289 ? 90.029  40.626 75.664  1.00 0.69 ? 289 GLN A NE2 1 
ATOM 2183 N N   . GLU A 1 290 ? 89.893  37.662 69.577  1.00 0.66 ? 290 GLU A N   1 
ATOM 2184 C CA  . GLU A 1 290 ? 90.665  37.491 68.357  1.00 0.66 ? 290 GLU A CA  1 
ATOM 2185 C C   . GLU A 1 290 ? 90.462  38.606 67.334  1.00 0.66 ? 290 GLU A C   1 
ATOM 2186 O O   . GLU A 1 290 ? 91.425  39.131 66.770  1.00 0.66 ? 290 GLU A O   1 
ATOM 2187 C CB  . GLU A 1 290 ? 90.292  36.151 67.702  1.00 0.66 ? 290 GLU A CB  1 
ATOM 2188 C CG  . GLU A 1 290 ? 90.751  34.917 68.503  1.00 0.66 ? 290 GLU A CG  1 
ATOM 2189 C CD  . GLU A 1 290 ? 90.374  33.666 67.718  1.00 0.66 ? 290 GLU A CD  1 
ATOM 2190 O OE1 . GLU A 1 290 ? 89.161  33.399 67.530  1.00 0.66 ? 290 GLU A OE1 1 
ATOM 2191 O OE2 . GLU A 1 290 ? 91.327  33.020 67.211  1.00 0.66 ? 290 GLU A OE2 1 
ATOM 2192 N N   . LEU A 1 291 ? 89.194  39.029 67.126  1.00 0.65 ? 291 LEU A N   1 
ATOM 2193 C CA  . LEU A 1 291 ? 88.822  40.196 66.341  1.00 0.65 ? 291 LEU A CA  1 
ATOM 2194 C C   . LEU A 1 291 ? 89.315  41.479 66.970  1.00 0.65 ? 291 LEU A C   1 
ATOM 2195 O O   . LEU A 1 291 ? 89.842  42.353 66.296  1.00 0.65 ? 291 LEU A O   1 
ATOM 2196 C CB  . LEU A 1 291 ? 87.285  40.249 66.125  1.00 0.65 ? 291 LEU A CB  1 
ATOM 2197 C CG  . LEU A 1 291 ? 86.740  41.432 65.284  1.00 0.65 ? 291 LEU A CG  1 
ATOM 2198 C CD1 . LEU A 1 291 ? 85.484  41.009 64.511  1.00 0.65 ? 291 LEU A CD1 1 
ATOM 2199 C CD2 . LEU A 1 291 ? 86.402  42.691 66.109  1.00 0.65 ? 291 LEU A CD2 1 
ATOM 2200 N N   . ILE A 1 292 ? 89.194  41.623 68.305  1.00 0.60 ? 292 ILE A N   1 
ATOM 2201 C CA  . ILE A 1 292 ? 89.648  42.807 69.025  1.00 0.60 ? 292 ILE A CA  1 
ATOM 2202 C C   . ILE A 1 292 ? 91.156  43.020 68.886  1.00 0.60 ? 292 ILE A C   1 
ATOM 2203 O O   . ILE A 1 292 ? 91.635  44.137 68.707  1.00 0.60 ? 292 ILE A O   1 
ATOM 2204 C CB  . ILE A 1 292 ? 89.218  42.770 70.492  1.00 0.60 ? 292 ILE A CB  1 
ATOM 2205 C CG1 . ILE A 1 292 ? 87.702  42.470 70.666  1.00 0.60 ? 292 ILE A CG1 1 
ATOM 2206 C CG2 . ILE A 1 292 ? 89.595  44.081 71.216  1.00 0.60 ? 292 ILE A CG2 1 
ATOM 2207 C CD1 . ILE A 1 292 ? 86.744  43.500 70.052  1.00 0.60 ? 292 ILE A CD1 1 
ATOM 2208 N N   . ARG A 1 293 ? 91.950  41.931 68.927  1.00 0.48 ? 293 ARG A N   1 
ATOM 2209 C CA  . ARG A 1 293 ? 93.373  41.959 68.644  1.00 0.48 ? 293 ARG A CA  1 
ATOM 2210 C C   . ARG A 1 293 ? 93.790  42.244 67.205  1.00 0.48 ? 293 ARG A C   1 
ATOM 2211 O O   . ARG A 1 293 ? 94.760  42.967 66.991  1.00 0.48 ? 293 ARG A O   1 
ATOM 2212 C CB  . ARG A 1 293 ? 94.020  40.622 69.070  1.00 0.48 ? 293 ARG A CB  1 
ATOM 2213 C CG  . ARG A 1 293 ? 94.229  40.475 70.589  1.00 0.48 ? 293 ARG A CG  1 
ATOM 2214 C CD  . ARG A 1 293 ? 95.587  40.986 71.101  1.00 0.48 ? 293 ARG A CD  1 
ATOM 2215 N NE  . ARG A 1 293 ? 95.637  42.489 71.015  1.00 0.48 ? 293 ARG A NE  1 
ATOM 2216 C CZ  . ARG A 1 293 ? 95.347  43.330 72.017  1.00 0.48 ? 293 ARG A CZ  1 
ATOM 2217 N NH1 . ARG A 1 293 ? 95.527  44.642 71.872  1.00 0.48 ? 293 ARG A NH1 1 
ATOM 2218 N NH2 . ARG A 1 293 ? 94.878  42.912 73.185  1.00 0.48 ? 293 ARG A NH2 1 
ATOM 2219 N N   . GLN A 1 294 ? 93.112  41.660 66.193  1.00 0.47 ? 294 GLN A N   1 
ATOM 2220 C CA  . GLN A 1 294 ? 93.424  41.901 64.787  1.00 0.47 ? 294 GLN A CA  1 
ATOM 2221 C C   . GLN A 1 294 ? 92.878  43.232 64.272  1.00 0.47 ? 294 GLN A C   1 
ATOM 2222 O O   . GLN A 1 294 ? 93.344  43.785 63.276  1.00 0.47 ? 294 GLN A O   1 
ATOM 2223 C CB  . GLN A 1 294 ? 92.841  40.738 63.930  1.00 0.47 ? 294 GLN A CB  1 
ATOM 2224 C CG  . GLN A 1 294 ? 92.980  40.854 62.384  1.00 0.47 ? 294 GLN A CG  1 
ATOM 2225 C CD  . GLN A 1 294 ? 94.424  40.991 61.898  1.00 0.47 ? 294 GLN A CD  1 
ATOM 2226 O OE1 . GLN A 1 294 ? 95.390  40.594 62.564  1.00 0.47 ? 294 GLN A OE1 1 
ATOM 2227 N NE2 . GLN A 1 294 ? 94.587  41.544 60.674  1.00 0.47 ? 294 GLN A NE2 1 
ATOM 2228 N N   . GLY A 1 295 ? 91.870  43.794 64.961  1.00 0.55 ? 295 GLY A N   1 
ATOM 2229 C CA  . GLY A 1 295 ? 91.003  44.834 64.434  1.00 0.55 ? 295 GLY A CA  1 
ATOM 2230 C C   . GLY A 1 295 ? 89.901  44.247 63.589  1.00 0.55 ? 295 GLY A C   1 
ATOM 2231 O O   . GLY A 1 295 ? 89.886  43.068 63.236  1.00 0.55 ? 295 GLY A O   1 
ATOM 2232 N N   . THR A 1 296 ? 88.924  45.085 63.196  1.00 0.56 ? 296 THR A N   1 
ATOM 2233 C CA  . THR A 1 296 ? 87.686  44.634 62.545  1.00 0.56 ? 296 THR A CA  1 
ATOM 2234 C C   . THR A 1 296 ? 87.871  44.280 61.058  1.00 0.56 ? 296 THR A C   1 
ATOM 2235 O O   . THR A 1 296 ? 86.952  43.891 60.345  1.00 0.56 ? 296 THR A O   1 
ATOM 2236 C CB  . THR A 1 296 ? 86.586  45.678 62.730  1.00 0.56 ? 296 THR A CB  1 
ATOM 2237 O OG1 . THR A 1 296 ? 86.377  45.994 64.093  1.00 0.56 ? 296 THR A OG1 1 
ATOM 2238 C CG2 . THR A 1 296 ? 85.189  45.258 62.278  1.00 0.56 ? 296 THR A CG2 1 
ATOM 2239 N N   . ASP A 1 297 ? 89.134  44.303 60.583  1.00 0.54 ? 297 ASP A N   1 
ATOM 2240 C CA  . ASP A 1 297 ? 89.665  43.630 59.407  1.00 0.54 ? 297 ASP A CA  1 
ATOM 2241 C C   . ASP A 1 297 ? 89.422  42.118 59.468  1.00 0.54 ? 297 ASP A C   1 
ATOM 2242 O O   . ASP A 1 297 ? 89.188  41.480 58.445  1.00 0.54 ? 297 ASP A O   1 
ATOM 2243 C CB  . ASP A 1 297 ? 91.183  43.965 59.394  1.00 0.54 ? 297 ASP A CB  1 
ATOM 2244 C CG  . ASP A 1 297 ? 91.982  43.303 58.282  1.00 0.54 ? 297 ASP A CG  1 
ATOM 2245 O OD1 . ASP A 1 297 ? 91.815  43.738 57.114  1.00 0.54 ? 297 ASP A OD1 1 
ATOM 2246 O OD2 . ASP A 1 297 ? 92.828  42.430 58.619  1.00 0.54 ? 297 ASP A OD2 1 
ATOM 2247 N N   . TYR A 1 298 ? 89.473  41.527 60.688  1.00 0.56 ? 298 TYR A N   1 
ATOM 2248 C CA  . TYR A 1 298 ? 89.305  40.111 60.967  1.00 0.56 ? 298 TYR A CA  1 
ATOM 2249 C C   . TYR A 1 298 ? 88.320  39.338 60.079  1.00 0.56 ? 298 TYR A C   1 
ATOM 2250 O O   . TYR A 1 298 ? 87.122  39.621 60.036  1.00 0.56 ? 298 TYR A O   1 
ATOM 2251 C CB  . TYR A 1 298 ? 88.986  39.927 62.475  1.00 0.56 ? 298 TYR A CB  1 
ATOM 2252 C CG  . TYR A 1 298 ? 88.996  38.496 62.940  1.00 0.56 ? 298 TYR A CG  1 
ATOM 2253 C CD1 . TYR A 1 298 ? 90.200  37.814 63.178  1.00 0.56 ? 298 TYR A CD1 1 
ATOM 2254 C CD2 . TYR A 1 298 ? 87.781  37.832 63.173  1.00 0.56 ? 298 TYR A CD2 1 
ATOM 2255 C CE1 . TYR A 1 298 ? 90.186  36.486 63.624  1.00 0.56 ? 298 TYR A CE1 1 
ATOM 2256 C CE2 . TYR A 1 298 ? 87.769  36.510 63.633  1.00 0.56 ? 298 TYR A CE2 1 
ATOM 2257 C CZ  . TYR A 1 298 ? 88.973  35.829 63.828  1.00 0.56 ? 298 TYR A CZ  1 
ATOM 2258 O OH  . TYR A 1 298 ? 88.982  34.476 64.205  1.00 0.56 ? 298 TYR A OH  1 
ATOM 2259 N N   . LYS A 1 299 ? 88.821  38.283 59.394  1.00 0.64 ? 299 LYS A N   1 
ATOM 2260 C CA  . LYS A 1 299 ? 88.140  37.584 58.305  1.00 0.64 ? 299 LYS A CA  1 
ATOM 2261 C C   . LYS A 1 299 ? 86.701  37.123 58.544  1.00 0.64 ? 299 LYS A C   1 
ATOM 2262 O O   . LYS A 1 299 ? 85.892  37.073 57.622  1.00 0.64 ? 299 LYS A O   1 
ATOM 2263 C CB  . LYS A 1 299 ? 88.971  36.361 57.823  1.00 0.64 ? 299 LYS A CB  1 
ATOM 2264 C CG  . LYS A 1 299 ? 90.011  36.716 56.748  1.00 0.64 ? 299 LYS A CG  1 
ATOM 2265 C CD  . LYS A 1 299 ? 90.721  35.466 56.198  1.00 0.64 ? 299 LYS A CD  1 
ATOM 2266 C CE  . LYS A 1 299 ? 91.561  35.738 54.944  1.00 0.64 ? 299 LYS A CE  1 
ATOM 2267 N NZ  . LYS A 1 299 ? 92.188  34.485 54.470  1.00 0.64 ? 299 LYS A NZ  1 
ATOM 2268 N N   . HIS A 1 300 ? 86.333  36.769 59.789  1.00 0.67 ? 300 HIS A N   1 
ATOM 2269 C CA  . HIS A 1 300 ? 84.978  36.346 60.108  1.00 0.67 ? 300 HIS A CA  1 
ATOM 2270 C C   . HIS A 1 300 ? 83.961  37.480 60.183  1.00 0.67 ? 300 HIS A C   1 
ATOM 2271 O O   . HIS A 1 300 ? 82.757  37.231 60.121  1.00 0.67 ? 300 HIS A O   1 
ATOM 2272 C CB  . HIS A 1 300 ? 84.919  35.601 61.453  1.00 0.67 ? 300 HIS A CB  1 
ATOM 2273 C CG  . HIS A 1 300 ? 85.775  34.379 61.499  1.00 0.67 ? 300 HIS A CG  1 
ATOM 2274 N ND1 . HIS A 1 300 ? 85.935  33.742 62.714  1.00 0.67 ? 300 HIS A ND1 1 
ATOM 2275 C CD2 . HIS A 1 300 ? 86.459  33.722 60.524  1.00 0.67 ? 300 HIS A CD2 1 
ATOM 2276 C CE1 . HIS A 1 300 ? 86.718  32.713 62.452  1.00 0.67 ? 300 HIS A CE1 1 
ATOM 2277 N NE2 . HIS A 1 300 ? 87.063  32.653 61.145  1.00 0.67 ? 300 HIS A NE2 1 
ATOM 2278 N N   . TRP A 1 301 ? 84.393  38.757 60.306  1.00 0.57 ? 301 TRP A N   1 
ATOM 2279 C CA  . TRP A 1 301 ? 83.495  39.881 60.545  1.00 0.57 ? 301 TRP A CA  1 
ATOM 2280 C C   . TRP A 1 301 ? 82.386  40.097 59.507  1.00 0.57 ? 301 TRP A C   1 
ATOM 2281 O O   . TRP A 1 301 ? 81.264  40.328 59.960  1.00 0.57 ? 301 TRP A O   1 
ATOM 2282 C CB  . TRP A 1 301 ? 84.260  41.206 60.833  1.00 0.57 ? 301 TRP A CB  1 
ATOM 2283 C CG  . TRP A 1 301 ? 83.363  42.412 61.118  1.00 0.57 ? 301 TRP A CG  1 
ATOM 2284 C CD1 . TRP A 1 301 ? 83.115  43.473 60.290  1.00 0.57 ? 301 TRP A CD1 1 
ATOM 2285 C CD2 . TRP A 1 301 ? 82.464  42.561 62.237  1.00 0.57 ? 301 TRP A CD2 1 
ATOM 2286 N NE1 . TRP A 1 301 ? 82.134  44.277 60.827  1.00 0.57 ? 301 TRP A NE1 1 
ATOM 2287 C CE2 . TRP A 1 301 ? 81.707  43.725 62.002  1.00 0.57 ? 301 TRP A CE2 1 
ATOM 2288 C CE3 . TRP A 1 301 ? 82.243  41.793 63.375  1.00 0.57 ? 301 TRP A CE3 1 
ATOM 2289 C CZ2 . TRP A 1 301 ? 80.716  44.127 62.882  1.00 0.57 ? 301 TRP A CZ2 1 
ATOM 2290 C CZ3 . TRP A 1 301 ? 81.262  42.217 64.285  1.00 0.57 ? 301 TRP A CZ3 1 
ATOM 2291 C CH2 . TRP A 1 301 ? 80.500  43.366 64.039  1.00 0.57 ? 301 TRP A CH2 1 
ATOM 2292 N N   . PRO A 1 302 ? 82.524  40.008 58.181  1.00 0.63 ? 302 PRO A N   1 
ATOM 2293 C CA  . PRO A 1 302 ? 81.400  40.149 57.255  1.00 0.63 ? 302 PRO A CA  1 
ATOM 2294 C C   . PRO A 1 302 ? 80.258  39.166 57.485  1.00 0.63 ? 302 PRO A C   1 
ATOM 2295 O O   . PRO A 1 302 ? 79.125  39.472 57.122  1.00 0.63 ? 302 PRO A O   1 
ATOM 2296 C CB  . PRO A 1 302 ? 82.040  39.996 55.864  1.00 0.63 ? 302 PRO A CB  1 
ATOM 2297 C CG  . PRO A 1 302 ? 83.483  40.462 56.066  1.00 0.63 ? 302 PRO A CG  1 
ATOM 2298 C CD  . PRO A 1 302 ? 83.805  39.956 57.470  1.00 0.63 ? 302 PRO A CD  1 
ATOM 2299 N N   . GLN A 1 303 ? 80.534  37.979 58.062  1.00 0.66 ? 303 GLN A N   1 
ATOM 2300 C CA  . GLN A 1 303 ? 79.517  37.034 58.479  1.00 0.66 ? 303 GLN A CA  1 
ATOM 2301 C C   . GLN A 1 303 ? 78.919  37.372 59.842  1.00 0.66 ? 303 GLN A C   1 
ATOM 2302 O O   . GLN A 1 303 ? 77.701  37.358 60.011  1.00 0.66 ? 303 GLN A O   1 
ATOM 2303 C CB  . GLN A 1 303 ? 80.062  35.591 58.457  1.00 0.66 ? 303 GLN A CB  1 
ATOM 2304 C CG  . GLN A 1 303 ? 80.573  35.189 57.053  1.00 0.66 ? 303 GLN A CG  1 
ATOM 2305 C CD  . GLN A 1 303 ? 80.386  33.689 56.798  1.00 0.66 ? 303 GLN A CD  1 
ATOM 2306 O OE1 . GLN A 1 303 ? 79.286  33.169 56.983  1.00 0.66 ? 303 GLN A OE1 1 
ATOM 2307 N NE2 . GLN A 1 303 ? 81.450  32.997 56.332  1.00 0.66 ? 303 GLN A NE2 1 
ATOM 2308 N N   . ILE A 1 304 ? 79.759  37.748 60.837  1.00 0.63 ? 304 ILE A N   1 
ATOM 2309 C CA  . ILE A 1 304 ? 79.340  38.140 62.186  1.00 0.63 ? 304 ILE A CA  1 
ATOM 2310 C C   . ILE A 1 304 ? 78.444  39.374 62.179  1.00 0.63 ? 304 ILE A C   1 
ATOM 2311 O O   . ILE A 1 304 ? 77.457  39.468 62.910  1.00 0.63 ? 304 ILE A O   1 
ATOM 2312 C CB  . ILE A 1 304 ? 80.534  38.408 63.110  1.00 0.63 ? 304 ILE A CB  1 
ATOM 2313 C CG1 . ILE A 1 304 ? 81.450  37.168 63.232  1.00 0.63 ? 304 ILE A CG1 1 
ATOM 2314 C CG2 . ILE A 1 304 ? 80.061  38.846 64.522  1.00 0.63 ? 304 ILE A CG2 1 
ATOM 2315 C CD1 . ILE A 1 304 ? 82.824  37.493 63.839  1.00 0.63 ? 304 ILE A CD1 1 
ATOM 2316 N N   . ALA A 1 305 ? 78.760  40.349 61.306  1.00 0.63 ? 305 ALA A N   1 
ATOM 2317 C CA  . ALA A 1 305 ? 78.039  41.590 61.122  1.00 0.63 ? 305 ALA A CA  1 
ATOM 2318 C C   . ALA A 1 305 ? 76.582  41.428 60.699  1.00 0.63 ? 305 ALA A C   1 
ATOM 2319 O O   . ALA A 1 305 ? 75.774  42.330 60.891  1.00 0.63 ? 305 ALA A O   1 
ATOM 2320 C CB  . ALA A 1 305 ? 78.789  42.439 60.074  1.00 0.63 ? 305 ALA A CB  1 
ATOM 2321 N N   . GLN A 1 306 ? 76.203  40.260 60.141  1.00 0.59 ? 306 GLN A N   1 
ATOM 2322 C CA  . GLN A 1 306 ? 74.835  39.956 59.772  1.00 0.59 ? 306 GLN A CA  1 
ATOM 2323 C C   . GLN A 1 306 ? 73.928  39.710 60.968  1.00 0.59 ? 306 GLN A C   1 
ATOM 2324 O O   . GLN A 1 306 ? 72.719  39.903 60.889  1.00 0.59 ? 306 GLN A O   1 
ATOM 2325 C CB  . GLN A 1 306 ? 74.777  38.697 58.868  1.00 0.59 ? 306 GLN A CB  1 
ATOM 2326 C CG  . GLN A 1 306 ? 75.713  38.730 57.635  1.00 0.59 ? 306 GLN A CG  1 
ATOM 2327 C CD  . GLN A 1 306 ? 75.496  39.971 56.772  1.00 0.59 ? 306 GLN A CD  1 
ATOM 2328 O OE1 . GLN A 1 306 ? 74.377  40.422 56.532  1.00 0.59 ? 306 GLN A OE1 1 
ATOM 2329 N NE2 . GLN A 1 306 ? 76.613  40.545 56.267  1.00 0.59 ? 306 GLN A NE2 1 
ATOM 2330 N N   . PHE A 1 307 ? 74.484  39.272 62.121  1.00 0.52 ? 307 PHE A N   1 
ATOM 2331 C CA  . PHE A 1 307 ? 73.715  38.899 63.298  1.00 0.52 ? 307 PHE A CA  1 
ATOM 2332 C C   . PHE A 1 307 ? 72.908  40.048 63.892  1.00 0.52 ? 307 PHE A C   1 
ATOM 2333 O O   . PHE A 1 307 ? 71.799  39.855 64.392  1.00 0.52 ? 307 PHE A O   1 
ATOM 2334 C CB  . PHE A 1 307 ? 74.603  38.258 64.397  1.00 0.52 ? 307 PHE A CB  1 
ATOM 2335 C CG  . PHE A 1 307 ? 75.375  37.037 63.955  1.00 0.52 ? 307 PHE A CG  1 
ATOM 2336 C CD1 . PHE A 1 307 ? 74.915  36.146 62.967  1.00 0.52 ? 307 PHE A CD1 1 
ATOM 2337 C CD2 . PHE A 1 307 ? 76.593  36.747 64.596  1.00 0.52 ? 307 PHE A CD2 1 
ATOM 2338 C CE1 . PHE A 1 307 ? 75.665  35.018 62.617  1.00 0.52 ? 307 PHE A CE1 1 
ATOM 2339 C CE2 . PHE A 1 307 ? 77.342  35.615 64.253  1.00 0.52 ? 307 PHE A CE2 1 
ATOM 2340 C CZ  . PHE A 1 307 ? 76.881  34.755 63.254  1.00 0.52 ? 307 PHE A CZ  1 
ATOM 2341 N N   . ALA A 1 308 ? 73.450  41.278 63.830  1.00 0.55 ? 308 ALA A N   1 
ATOM 2342 C CA  . ALA A 1 308 ? 72.731  42.491 64.145  1.00 0.55 ? 308 ALA A CA  1 
ATOM 2343 C C   . ALA A 1 308 ? 72.101  43.073 62.868  1.00 0.55 ? 308 ALA A C   1 
ATOM 2344 O O   . ALA A 1 308 ? 72.832  43.325 61.912  1.00 0.55 ? 308 ALA A O   1 
ATOM 2345 C CB  . ALA A 1 308 ? 73.698  43.523 64.759  1.00 0.55 ? 308 ALA A CB  1 
ATOM 2346 N N   . PRO A 1 309 ? 70.797  43.303 62.744  1.00 0.51 ? 309 PRO A N   1 
ATOM 2347 C CA  . PRO A 1 309 ? 70.208  43.880 61.540  1.00 0.51 ? 309 PRO A CA  1 
ATOM 2348 C C   . PRO A 1 309 ? 70.487  45.361 61.369  1.00 0.51 ? 309 PRO A C   1 
ATOM 2349 O O   . PRO A 1 309 ? 70.648  46.088 62.347  1.00 0.51 ? 309 PRO A O   1 
ATOM 2350 C CB  . PRO A 1 309 ? 68.696  43.682 61.736  1.00 0.51 ? 309 PRO A CB  1 
ATOM 2351 C CG  . PRO A 1 309 ? 68.517  43.674 63.256  1.00 0.51 ? 309 PRO A CG  1 
ATOM 2352 C CD  . PRO A 1 309 ? 69.802  43.035 63.776  1.00 0.51 ? 309 PRO A CD  1 
ATOM 2353 N N   . SER A 1 310 ? 70.480  45.839 60.105  1.00 0.52 ? 310 SER A N   1 
ATOM 2354 C CA  . SER A 1 310 ? 70.338  47.254 59.777  1.00 0.52 ? 310 SER A CA  1 
ATOM 2355 C C   . SER A 1 310 ? 68.963  47.772 60.179  1.00 0.52 ? 310 SER A C   1 
ATOM 2356 O O   . SER A 1 310 ? 67.990  47.020 60.212  1.00 0.52 ? 310 SER A O   1 
ATOM 2357 C CB  . SER A 1 310 ? 70.586  47.546 58.269  1.00 0.52 ? 310 SER A CB  1 
ATOM 2358 O OG  . SER A 1 310 ? 70.554  48.943 57.960  1.00 0.52 ? 310 SER A OG  1 
ATOM 2359 N N   . ALA A 1 311 ? 68.846  49.080 60.480  1.00 0.55 ? 311 ALA A N   1 
ATOM 2360 C CA  . ALA A 1 311 ? 67.660  49.733 61.005  1.00 0.55 ? 311 ALA A CA  1 
ATOM 2361 C C   . ALA A 1 311 ? 66.392  49.573 60.159  1.00 0.55 ? 311 ALA A C   1 
ATOM 2362 O O   . ALA A 1 311 ? 65.288  49.491 60.691  1.00 0.55 ? 311 ALA A O   1 
ATOM 2363 C CB  . ALA A 1 311 ? 67.968  51.225 61.254  1.00 0.55 ? 311 ALA A CB  1 
ATOM 2364 N N   . SER A 1 312 ? 66.533  49.494 58.820  1.00 0.45 ? 312 SER A N   1 
ATOM 2365 C CA  . SER A 1 312 ? 65.465  49.189 57.877  1.00 0.45 ? 312 SER A CA  1 
ATOM 2366 C C   . SER A 1 312 ? 64.880  47.788 58.042  1.00 0.45 ? 312 SER A C   1 
ATOM 2367 O O   . SER A 1 312 ? 63.674  47.588 57.931  1.00 0.45 ? 312 SER A O   1 
ATOM 2368 C CB  . SER A 1 312 ? 65.945  49.392 56.412  1.00 0.45 ? 312 SER A CB  1 
ATOM 2369 O OG  . SER A 1 312 ? 67.127  48.635 56.132  1.00 0.45 ? 312 SER A OG  1 
ATOM 2370 N N   . ALA A 1 313 ? 65.725  46.777 58.336  1.00 0.50 ? 313 ALA A N   1 
ATOM 2371 C CA  . ALA A 1 313 ? 65.310  45.399 58.504  1.00 0.50 ? 313 ALA A CA  1 
ATOM 2372 C C   . ALA A 1 313 ? 64.959  45.046 59.949  1.00 0.50 ? 313 ALA A C   1 
ATOM 2373 O O   . ALA A 1 313 ? 64.331  44.023 60.219  1.00 0.50 ? 313 ALA A O   1 
ATOM 2374 C CB  . ALA A 1 313 ? 66.482  44.493 58.077  1.00 0.50 ? 313 ALA A CB  1 
ATOM 2375 N N   . PHE A 1 314 ? 65.342  45.905 60.914  1.00 0.41 ? 314 PHE A N   1 
ATOM 2376 C CA  . PHE A 1 314 ? 65.293  45.665 62.348  1.00 0.41 ? 314 PHE A CA  1 
ATOM 2377 C C   . PHE A 1 314 ? 63.908  45.342 62.896  1.00 0.41 ? 314 PHE A C   1 
ATOM 2378 O O   . PHE A 1 314 ? 63.744  44.392 63.658  1.00 0.41 ? 314 PHE A O   1 
ATOM 2379 C CB  . PHE A 1 314 ? 65.933  46.897 63.049  1.00 0.41 ? 314 PHE A CB  1 
ATOM 2380 C CG  . PHE A 1 314 ? 66.148  46.830 64.544  1.00 0.41 ? 314 PHE A CG  1 
ATOM 2381 C CD1 . PHE A 1 314 ? 66.290  45.635 65.272  1.00 0.41 ? 314 PHE A CD1 1 
ATOM 2382 C CD2 . PHE A 1 314 ? 66.278  48.049 65.232  1.00 0.41 ? 314 PHE A CD2 1 
ATOM 2383 C CE1 . PHE A 1 314 ? 66.569  45.662 66.645  1.00 0.41 ? 314 PHE A CE1 1 
ATOM 2384 C CE2 . PHE A 1 314 ? 66.531  48.079 66.606  1.00 0.41 ? 314 PHE A CE2 1 
ATOM 2385 C CZ  . PHE A 1 314 ? 66.692  46.883 67.309  1.00 0.41 ? 314 PHE A CZ  1 
ATOM 2386 N N   . PHE A 1 315 ? 62.867  46.073 62.452  1.00 0.36 ? 315 PHE A N   1 
ATOM 2387 C CA  . PHE A 1 315 ? 61.475  45.865 62.822  1.00 0.36 ? 315 PHE A CA  1 
ATOM 2388 C C   . PHE A 1 315 ? 60.928  44.504 62.364  1.00 0.36 ? 315 PHE A C   1 
ATOM 2389 O O   . PHE A 1 315 ? 60.031  43.927 62.970  1.00 0.36 ? 315 PHE A O   1 
ATOM 2390 C CB  . PHE A 1 315 ? 60.656  47.062 62.262  1.00 0.36 ? 315 PHE A CB  1 
ATOM 2391 C CG  . PHE A 1 315 ? 59.230  47.087 62.741  1.00 0.36 ? 315 PHE A CG  1 
ATOM 2392 C CD1 . PHE A 1 315 ? 58.923  47.397 64.075  1.00 0.36 ? 315 PHE A CD1 1 
ATOM 2393 C CD2 . PHE A 1 315 ? 58.184  46.818 61.848  1.00 0.36 ? 315 PHE A CD2 1 
ATOM 2394 C CE1 . PHE A 1 315 ? 57.591  47.444 64.507  1.00 0.36 ? 315 PHE A CE1 1 
ATOM 2395 C CE2 . PHE A 1 315 ? 56.851  46.860 62.276  1.00 0.36 ? 315 PHE A CE2 1 
ATOM 2396 C CZ  . PHE A 1 315 ? 56.554  47.178 63.606  1.00 0.36 ? 315 PHE A CZ  1 
ATOM 2397 N N   . GLY A 1 316 ? 61.488  43.920 61.279  1.00 0.46 ? 316 GLY A N   1 
ATOM 2398 C CA  . GLY A 1 316 ? 61.115  42.579 60.840  1.00 0.46 ? 316 GLY A CA  1 
ATOM 2399 C C   . GLY A 1 316 ? 61.826  41.457 61.553  1.00 0.46 ? 316 GLY A C   1 
ATOM 2400 O O   . GLY A 1 316 ? 61.503  40.285 61.340  1.00 0.46 ? 316 GLY A O   1 
ATOM 2401 N N   . MET A 1 317 ? 62.824  41.793 62.395  1.00 0.39 ? 317 MET A N   1 
ATOM 2402 C CA  . MET A 1 317 ? 63.646  40.840 63.110  1.00 0.39 ? 317 MET A CA  1 
ATOM 2403 C C   . MET A 1 317 ? 63.471  40.925 64.619  1.00 0.39 ? 317 MET A C   1 
ATOM 2404 O O   . MET A 1 317 ? 63.767  39.968 65.326  1.00 0.39 ? 317 MET A O   1 
ATOM 2405 C CB  . MET A 1 317 ? 65.139  41.090 62.767  1.00 0.39 ? 317 MET A CB  1 
ATOM 2406 C CG  . MET A 1 317 ? 65.483  40.885 61.277  1.00 0.39 ? 317 MET A CG  1 
ATOM 2407 S SD  . MET A 1 317 ? 65.254  39.174 60.723  1.00 0.39 ? 317 MET A SD  1 
ATOM 2408 C CE  . MET A 1 317 ? 65.852  39.399 59.029  1.00 0.39 ? 317 MET A CE  1 
ATOM 2409 N N   . SER A 1 318 ? 62.953  42.042 65.157  1.00 0.43 ? 318 SER A N   1 
ATOM 2410 C CA  . SER A 1 318 ? 62.830  42.229 66.588  1.00 0.43 ? 318 SER A CA  1 
ATOM 2411 C C   . SER A 1 318 ? 61.695  43.189 66.865  1.00 0.43 ? 318 SER A C   1 
ATOM 2412 O O   . SER A 1 318 ? 61.366  44.045 66.048  1.00 0.43 ? 318 SER A O   1 
ATOM 2413 C CB  . SER A 1 318 ? 64.127  42.859 67.164  1.00 0.43 ? 318 SER A CB  1 
ATOM 2414 O OG  . SER A 1 318 ? 64.098  43.116 68.571  1.00 0.43 ? 318 SER A OG  1 
ATOM 2415 N N   . ARG A 1 319 ? 61.070  43.082 68.055  1.00 0.36 ? 319 ARG A N   1 
ATOM 2416 C CA  . ARG A 1 319 ? 60.235  44.125 68.622  1.00 0.36 ? 319 ARG A CA  1 
ATOM 2417 C C   . ARG A 1 319 ? 60.993  45.429 68.854  1.00 0.36 ? 319 ARG A C   1 
ATOM 2418 O O   . ARG A 1 319 ? 62.161  45.412 69.234  1.00 0.36 ? 319 ARG A O   1 
ATOM 2419 C CB  . ARG A 1 319 ? 59.612  43.677 69.974  1.00 0.36 ? 319 ARG A CB  1 
ATOM 2420 C CG  . ARG A 1 319 ? 60.623  43.261 71.075  1.00 0.36 ? 319 ARG A CG  1 
ATOM 2421 C CD  . ARG A 1 319 ? 59.930  42.879 72.388  1.00 0.36 ? 319 ARG A CD  1 
ATOM 2422 N NE  . ARG A 1 319 ? 60.955  42.379 73.363  1.00 0.36 ? 319 ARG A NE  1 
ATOM 2423 C CZ  . ARG A 1 319 ? 60.646  41.949 74.598  1.00 0.36 ? 319 ARG A CZ  1 
ATOM 2424 N NH1 . ARG A 1 319 ? 61.604  41.475 75.394  1.00 0.36 ? 319 ARG A NH1 1 
ATOM 2425 N NH2 . ARG A 1 319 ? 59.414  42.024 75.078  1.00 0.36 ? 319 ARG A NH2 1 
ATOM 2426 N N   . ILE A 1 320 ? 60.344  46.594 68.643  1.00 0.42 ? 320 ILE A N   1 
ATOM 2427 C CA  . ILE A 1 320 ? 60.986  47.890 68.812  1.00 0.42 ? 320 ILE A CA  1 
ATOM 2428 C C   . ILE A 1 320 ? 60.080  48.752 69.671  1.00 0.42 ? 320 ILE A C   1 
ATOM 2429 O O   . ILE A 1 320 ? 58.865  48.792 69.479  1.00 0.42 ? 320 ILE A O   1 
ATOM 2430 C CB  . ILE A 1 320 ? 61.311  48.568 67.473  1.00 0.42 ? 320 ILE A CB  1 
ATOM 2431 C CG1 . ILE A 1 320 ? 62.360  47.725 66.698  1.00 0.42 ? 320 ILE A CG1 1 
ATOM 2432 C CG2 . ILE A 1 320 ? 61.816  50.016 67.694  1.00 0.42 ? 320 ILE A CG2 1 
ATOM 2433 C CD1 . ILE A 1 320 ? 62.787  48.313 65.349  1.00 0.42 ? 320 ILE A CD1 1 
ATOM 2434 N N   . GLY A 1 321 ? 60.654  49.453 70.670  1.00 0.53 ? 321 GLY A N   1 
ATOM 2435 C CA  . GLY A 1 321 ? 59.932  50.403 71.501  1.00 0.53 ? 321 GLY A CA  1 
ATOM 2436 C C   . GLY A 1 321 ? 60.924  51.087 72.399  1.00 0.53 ? 321 GLY A C   1 
ATOM 2437 O O   . GLY A 1 321 ? 62.120  51.052 72.113  1.00 0.53 ? 321 GLY A O   1 
ATOM 2438 N N   . MET A 1 322 ? 60.475  51.706 73.510  1.00 0.43 ? 322 MET A N   1 
ATOM 2439 C CA  . MET A 1 322 ? 61.374  52.260 74.511  1.00 0.43 ? 322 MET A CA  1 
ATOM 2440 C C   . MET A 1 322 ? 60.845  52.041 75.920  1.00 0.43 ? 322 MET A C   1 
ATOM 2441 O O   . MET A 1 322 ? 59.645  51.863 76.129  1.00 0.43 ? 322 MET A O   1 
ATOM 2442 C CB  . MET A 1 322 ? 61.618  53.786 74.346  1.00 0.43 ? 322 MET A CB  1 
ATOM 2443 C CG  . MET A 1 322 ? 62.489  54.147 73.129  1.00 0.43 ? 322 MET A CG  1 
ATOM 2444 S SD  . MET A 1 322 ? 63.353  55.741 73.275  1.00 0.43 ? 322 MET A SD  1 
ATOM 2445 C CE  . MET A 1 322 ? 61.877  56.787 73.168  1.00 0.43 ? 322 MET A CE  1 
ATOM 2446 N N   . GLU A 1 323 ? 61.756  52.093 76.915  1.00 0.48 ? 323 GLU A N   1 
ATOM 2447 C CA  . GLU A 1 323 ? 61.468  51.951 78.327  1.00 0.48 ? 323 GLU A CA  1 
ATOM 2448 C C   . GLU A 1 323 ? 62.237  52.999 79.135  1.00 0.48 ? 323 GLU A C   1 
ATOM 2449 O O   . GLU A 1 323 ? 63.272  53.515 78.713  1.00 0.48 ? 323 GLU A O   1 
ATOM 2450 C CB  . GLU A 1 323 ? 61.817  50.516 78.804  1.00 0.48 ? 323 GLU A CB  1 
ATOM 2451 C CG  . GLU A 1 323 ? 63.309  50.108 78.698  1.00 0.48 ? 323 GLU A CG  1 
ATOM 2452 C CD  . GLU A 1 323 ? 63.477  48.589 78.808  1.00 0.48 ? 323 GLU A CD  1 
ATOM 2453 O OE1 . GLU A 1 323 ? 62.937  47.867 77.922  1.00 0.48 ? 323 GLU A OE1 1 
ATOM 2454 O OE2 . GLU A 1 323 ? 64.127  48.146 79.790  1.00 0.48 ? 323 GLU A OE2 1 
ATOM 2455 N N   . VAL A 1 324 ? 61.699  53.418 80.308  1.00 0.44 ? 324 VAL A N   1 
ATOM 2456 C CA  . VAL A 1 324 ? 62.336  54.367 81.221  1.00 0.44 ? 324 VAL A CA  1 
ATOM 2457 C C   . VAL A 1 324 ? 63.569  53.811 81.951  1.00 0.44 ? 324 VAL A C   1 
ATOM 2458 O O   . VAL A 1 324 ? 63.576  52.670 82.403  1.00 0.44 ? 324 VAL A O   1 
ATOM 2459 C CB  . VAL A 1 324 ? 61.348  54.957 82.241  1.00 0.44 ? 324 VAL A CB  1 
ATOM 2460 C CG1 . VAL A 1 324 ? 60.314  55.847 81.518  1.00 0.44 ? 324 VAL A CG1 1 
ATOM 2461 C CG2 . VAL A 1 324 ? 60.639  53.856 83.063  1.00 0.44 ? 324 VAL A CG2 1 
ATOM 2462 N N   . THR A 1 325 ? 64.651  54.614 82.117  1.00 0.48 ? 325 THR A N   1 
ATOM 2463 C CA  . THR A 1 325 ? 65.848  54.187 82.836  1.00 0.48 ? 325 THR A CA  1 
ATOM 2464 C C   . THR A 1 325 ? 66.382  55.347 83.668  1.00 0.48 ? 325 THR A C   1 
ATOM 2465 O O   . THR A 1 325 ? 65.911  56.479 83.515  1.00 0.48 ? 325 THR A O   1 
ATOM 2466 C CB  . THR A 1 325 ? 67.000  53.565 82.012  1.00 0.48 ? 325 THR A CB  1 
ATOM 2467 O OG1 . THR A 1 325 ? 67.771  54.467 81.239  1.00 0.48 ? 325 THR A OG1 1 
ATOM 2468 C CG2 . THR A 1 325 ? 66.532  52.437 81.082  1.00 0.48 ? 325 THR A CG2 1 
ATOM 2469 N N   . PRO A 1 326 ? 67.364  55.151 84.564  1.00 0.44 ? 326 PRO A N   1 
ATOM 2470 C CA  . PRO A 1 326 ? 68.095  56.227 85.224  1.00 0.44 ? 326 PRO A CA  1 
ATOM 2471 C C   . PRO A 1 326 ? 68.919  57.111 84.313  1.00 0.44 ? 326 PRO A C   1 
ATOM 2472 O O   . PRO A 1 326 ? 69.615  57.973 84.842  1.00 0.44 ? 326 PRO A O   1 
ATOM 2473 C CB  . PRO A 1 326 ? 69.040  55.513 86.199  1.00 0.44 ? 326 PRO A CB  1 
ATOM 2474 C CG  . PRO A 1 326 ? 68.317  54.212 86.529  1.00 0.44 ? 326 PRO A CG  1 
ATOM 2475 C CD  . PRO A 1 326 ? 67.633  53.864 85.212  1.00 0.44 ? 326 PRO A CD  1 
ATOM 2476 N N   . SER A 1 327 ? 68.922  56.860 82.989  1.00 0.47 ? 327 SER A N   1 
ATOM 2477 C CA  . SER A 1 327 ? 69.587  57.670 81.989  1.00 0.47 ? 327 SER A CA  1 
ATOM 2478 C C   . SER A 1 327 ? 68.569  58.247 81.017  1.00 0.47 ? 327 SER A C   1 
ATOM 2479 O O   . SER A 1 327 ? 68.928  58.677 79.926  1.00 0.47 ? 327 SER A O   1 
ATOM 2480 C CB  . SER A 1 327 ? 70.630  56.894 81.150  1.00 0.47 ? 327 SER A CB  1 
ATOM 2481 O OG  . SER A 1 327 ? 71.640  56.307 81.980  1.00 0.47 ? 327 SER A OG  1 
ATOM 2482 N N   . GLY A 1 328 ? 67.263  58.274 81.383  1.00 0.46 ? 328 GLY A N   1 
ATOM 2483 C CA  . GLY A 1 328 ? 66.176  58.676 80.487  1.00 0.46 ? 328 GLY A CA  1 
ATOM 2484 C C   . GLY A 1 328 ? 65.625  57.519 79.684  1.00 0.46 ? 328 GLY A C   1 
ATOM 2485 O O   . GLY A 1 328 ? 66.002  56.370 79.877  1.00 0.46 ? 328 GLY A O   1 
ATOM 2486 N N   . THR A 1 329 ? 64.643  57.749 78.786  1.00 0.46 ? 329 THR A N   1 
ATOM 2487 C CA  . THR A 1 329 ? 64.092  56.694 77.939  1.00 0.46 ? 329 THR A CA  1 
ATOM 2488 C C   . THR A 1 329 ? 65.083  56.115 76.928  1.00 0.46 ? 329 THR A C   1 
ATOM 2489 O O   . THR A 1 329 ? 65.780  56.855 76.237  1.00 0.46 ? 329 THR A O   1 
ATOM 2490 C CB  . THR A 1 329 ? 62.819  57.119 77.200  1.00 0.46 ? 329 THR A CB  1 
ATOM 2491 O OG1 . THR A 1 329 ? 62.925  58.396 76.581  1.00 0.46 ? 329 THR A OG1 1 
ATOM 2492 C CG2 . THR A 1 329 ? 61.660  57.266 78.194  1.00 0.46 ? 329 THR A CG2 1 
ATOM 2493 N N   . TRP A 1 330 ? 65.148  54.770 76.785  1.00 0.40 ? 330 TRP A N   1 
ATOM 2494 C CA  . TRP A 1 330 ? 65.980  54.153 75.759  1.00 0.40 ? 330 TRP A CA  1 
ATOM 2495 C C   . TRP A 1 330 ? 65.310  52.915 75.171  1.00 0.40 ? 330 TRP A C   1 
ATOM 2496 O O   . TRP A 1 330 ? 64.298  52.447 75.676  1.00 0.40 ? 330 TRP A O   1 
ATOM 2497 C CB  . TRP A 1 330 ? 67.426  53.835 76.242  1.00 0.40 ? 330 TRP A CB  1 
ATOM 2498 C CG  . TRP A 1 330 ? 68.419  53.542 75.117  1.00 0.40 ? 330 TRP A CG  1 
ATOM 2499 C CD1 . TRP A 1 330 ? 68.803  54.399 74.126  1.00 0.40 ? 330 TRP A CD1 1 
ATOM 2500 C CD2 . TRP A 1 330 ? 68.968  52.253 74.766  1.00 0.40 ? 330 TRP A CD2 1 
ATOM 2501 N NE1 . TRP A 1 330 ? 69.572  53.739 73.192  1.00 0.40 ? 330 TRP A NE1 1 
ATOM 2502 C CE2 . TRP A 1 330 ? 69.663  52.418 73.551  1.00 0.40 ? 330 TRP A CE2 1 
ATOM 2503 C CE3 . TRP A 1 330 ? 68.864  51.002 75.360  1.00 0.40 ? 330 TRP A CE3 1 
ATOM 2504 C CZ2 . TRP A 1 330 ? 70.249  51.336 72.908  1.00 0.40 ? 330 TRP A CZ2 1 
ATOM 2505 C CZ3 . TRP A 1 330 ? 69.455  49.909 74.710  1.00 0.40 ? 330 TRP A CZ3 1 
ATOM 2506 C CH2 . TRP A 1 330 ? 70.133  50.070 73.494  1.00 0.40 ? 330 TRP A CH2 1 
ATOM 2507 N N   . LEU A 1 331 ? 65.862  52.423 74.037  1.00 0.49 ? 331 LEU A N   1 
ATOM 2508 C CA  . LEU A 1 331 ? 65.425  51.322 73.195  1.00 0.49 ? 331 LEU A CA  1 
ATOM 2509 C C   . LEU A 1 331 ? 65.137  49.988 73.871  1.00 0.49 ? 331 LEU A C   1 
ATOM 2510 O O   . LEU A 1 331 ? 65.965  49.420 74.580  1.00 0.49 ? 331 LEU A O   1 
ATOM 2511 C CB  . LEU A 1 331 ? 66.518  51.070 72.119  1.00 0.49 ? 331 LEU A CB  1 
ATOM 2512 C CG  . LEU A 1 331 ? 66.262  49.948 71.084  1.00 0.49 ? 331 LEU A CG  1 
ATOM 2513 C CD1 . LEU A 1 331 ? 65.102  50.270 70.128  1.00 0.49 ? 331 LEU A CD1 1 
ATOM 2514 C CD2 . LEU A 1 331 ? 67.550  49.647 70.298  1.00 0.49 ? 331 LEU A CD2 1 
ATOM 2515 N N   . THR A 1 332 ? 63.959  49.426 73.543  1.00 0.53 ? 332 THR A N   1 
ATOM 2516 C CA  . THR A 1 332 ? 63.507  48.102 73.936  1.00 0.53 ? 332 THR A CA  1 
ATOM 2517 C C   . THR A 1 332 ? 63.634  47.195 72.730  1.00 0.53 ? 332 THR A C   1 
ATOM 2518 O O   . THR A 1 332 ? 62.994  47.442 71.709  1.00 0.53 ? 332 THR A O   1 
ATOM 2519 C CB  . THR A 1 332 ? 62.025  48.077 74.300  1.00 0.53 ? 332 THR A CB  1 
ATOM 2520 O OG1 . THR A 1 332 ? 61.685  49.092 75.222  1.00 0.53 ? 332 THR A OG1 1 
ATOM 2521 C CG2 . THR A 1 332 ? 61.623  46.719 74.899  1.00 0.53 ? 332 THR A CG2 1 
ATOM 2522 N N   . TYR A 1 333 ? 64.447  46.115 72.790  1.00 0.40 ? 333 TYR A N   1 
ATOM 2523 C CA  . TYR A 1 333 ? 64.647  45.231 71.648  1.00 0.40 ? 333 TYR A CA  1 
ATOM 2524 C C   . TYR A 1 333 ? 65.137  43.856 72.109  1.00 0.40 ? 333 TYR A C   1 
ATOM 2525 O O   . TYR A 1 333 ? 65.656  43.732 73.218  1.00 0.40 ? 333 TYR A O   1 
ATOM 2526 C CB  . TYR A 1 333 ? 65.617  45.848 70.590  1.00 0.40 ? 333 TYR A CB  1 
ATOM 2527 C CG  . TYR A 1 333 ? 67.084  45.682 70.921  1.00 0.40 ? 333 TYR A CG  1 
ATOM 2528 C CD1 . TYR A 1 333 ? 67.697  46.416 71.949  1.00 0.40 ? 333 TYR A CD1 1 
ATOM 2529 C CD2 . TYR A 1 333 ? 67.844  44.719 70.232  1.00 0.40 ? 333 TYR A CD2 1 
ATOM 2530 C CE1 . TYR A 1 333 ? 69.055  46.229 72.242  1.00 0.40 ? 333 TYR A CE1 1 
ATOM 2531 C CE2 . TYR A 1 333 ? 69.195  44.525 70.531  1.00 0.40 ? 333 TYR A CE2 1 
ATOM 2532 C CZ  . TYR A 1 333 ? 69.809  45.311 71.505  1.00 0.40 ? 333 TYR A CZ  1 
ATOM 2533 O OH  . TYR A 1 333 ? 71.197  45.207 71.693  1.00 0.40 ? 333 TYR A OH  1 
ATOM 2534 N N   . THR A 1 334 ? 64.992  42.785 71.292  1.00 0.44 ? 334 THR A N   1 
ATOM 2535 C CA  . THR A 1 334 ? 65.448  41.451 71.687  1.00 0.44 ? 334 THR A CA  1 
ATOM 2536 C C   . THR A 1 334 ? 65.893  40.604 70.498  1.00 0.44 ? 334 THR A C   1 
ATOM 2537 O O   . THR A 1 334 ? 65.130  40.425 69.559  1.00 0.44 ? 334 THR A O   1 
ATOM 2538 C CB  . THR A 1 334 ? 64.320  40.619 72.301  1.00 0.44 ? 334 THR A CB  1 
ATOM 2539 O OG1 . THR A 1 334 ? 63.645  41.244 73.374  1.00 0.44 ? 334 THR A OG1 1 
ATOM 2540 C CG2 . THR A 1 334 ? 64.839  39.337 72.953  1.00 0.44 ? 334 THR A CG2 1 
ATOM 2541 N N   . GLY A 1 335 ? 67.090  39.963 70.550  1.00 0.48 ? 335 GLY A N   1 
ATOM 2542 C CA  . GLY A 1 335 ? 67.472  38.895 69.610  1.00 0.48 ? 335 GLY A CA  1 
ATOM 2543 C C   . GLY A 1 335 ? 68.219  39.278 68.346  1.00 0.48 ? 335 GLY A C   1 
ATOM 2544 O O   . GLY A 1 335 ? 68.219  40.420 67.896  1.00 0.48 ? 335 GLY A O   1 
ATOM 2545 N N   . ALA A 1 336 ? 68.925  38.279 67.763  1.00 0.50 ? 336 ALA A N   1 
ATOM 2546 C CA  . ALA A 1 336 ? 69.609  38.355 66.483  1.00 0.50 ? 336 ALA A CA  1 
ATOM 2547 C C   . ALA A 1 336 ? 68.659  38.150 65.301  1.00 0.50 ? 336 ALA A C   1 
ATOM 2548 O O   . ALA A 1 336 ? 67.487  37.826 65.471  1.00 0.50 ? 336 ALA A O   1 
ATOM 2549 C CB  . ALA A 1 336 ? 70.721  37.277 66.424  1.00 0.50 ? 336 ALA A CB  1 
ATOM 2550 N N   . ILE A 1 337 ? 69.148  38.348 64.057  1.00 0.45 ? 337 ILE A N   1 
ATOM 2551 C CA  . ILE A 1 337 ? 68.388  38.073 62.840  1.00 0.45 ? 337 ILE A CA  1 
ATOM 2552 C C   . ILE A 1 337 ? 67.906  36.634 62.650  1.00 0.45 ? 337 ILE A C   1 
ATOM 2553 O O   . ILE A 1 337 ? 68.507  35.657 63.095  1.00 0.45 ? 337 ILE A O   1 
ATOM 2554 C CB  . ILE A 1 337 ? 69.081  38.503 61.545  1.00 0.45 ? 337 ILE A CB  1 
ATOM 2555 C CG1 . ILE A 1 337 ? 70.308  37.634 61.176  1.00 0.45 ? 337 ILE A CG1 1 
ATOM 2556 C CG2 . ILE A 1 337 ? 69.444  39.999 61.633  1.00 0.45 ? 337 ILE A CG2 1 
ATOM 2557 C CD1 . ILE A 1 337 ? 70.692  37.753 59.696  1.00 0.45 ? 337 ILE A CD1 1 
ATOM 2558 N N   . LYS A 1 338 ? 66.772  36.475 61.943  1.00 0.43 ? 338 LYS A N   1 
ATOM 2559 C CA  . LYS A 1 338 ? 66.281  35.201 61.449  1.00 0.43 ? 338 LYS A CA  1 
ATOM 2560 C C   . LYS A 1 338 ? 67.144  34.621 60.326  1.00 0.43 ? 338 LYS A C   1 
ATOM 2561 O O   . LYS A 1 338 ? 67.735  35.363 59.545  1.00 0.43 ? 338 LYS A O   1 
ATOM 2562 C CB  . LYS A 1 338 ? 64.830  35.354 60.934  1.00 0.43 ? 338 LYS A CB  1 
ATOM 2563 C CG  . LYS A 1 338 ? 63.852  35.807 62.032  1.00 0.43 ? 338 LYS A CG  1 
ATOM 2564 C CD  . LYS A 1 338 ? 62.407  36.000 61.534  1.00 0.43 ? 338 LYS A CD  1 
ATOM 2565 C CE  . LYS A 1 338 ? 62.256  37.190 60.581  1.00 0.43 ? 338 LYS A CE  1 
ATOM 2566 N NZ  . LYS A 1 338 ? 60.840  37.416 60.223  1.00 0.43 ? 338 LYS A NZ  1 
ATOM 2567 N N   . LEU A 1 339 ? 67.208  33.279 60.199  1.00 0.42 ? 339 LEU A N   1 
ATOM 2568 C CA  . LEU A 1 339 ? 68.008  32.606 59.189  1.00 0.42 ? 339 LEU A CA  1 
ATOM 2569 C C   . LEU A 1 339 ? 67.196  31.473 58.575  1.00 0.42 ? 339 LEU A C   1 
ATOM 2570 O O   . LEU A 1 339 ? 66.203  31.045 59.159  1.00 0.42 ? 339 LEU A O   1 
ATOM 2571 C CB  . LEU A 1 339 ? 69.302  32.009 59.808  1.00 0.42 ? 339 LEU A CB  1 
ATOM 2572 C CG  . LEU A 1 339 ? 70.370  33.041 60.232  1.00 0.42 ? 339 LEU A CG  1 
ATOM 2573 C CD1 . LEU A 1 339 ? 71.528  32.346 60.966  1.00 0.42 ? 339 LEU A CD1 1 
ATOM 2574 C CD2 . LEU A 1 339 ? 70.911  33.836 59.033  1.00 0.42 ? 339 LEU A CD2 1 
ATOM 2575 N N   . ASP A 1 340 ? 67.615  30.982 57.388  1.00 0.42 ? 340 ASP A N   1 
ATOM 2576 C CA  . ASP A 1 340 ? 67.018  29.868 56.674  1.00 0.42 ? 340 ASP A CA  1 
ATOM 2577 C C   . ASP A 1 340 ? 68.091  28.784 56.570  1.00 0.42 ? 340 ASP A C   1 
ATOM 2578 O O   . ASP A 1 340 ? 69.218  29.056 56.153  1.00 0.42 ? 340 ASP A O   1 
ATOM 2579 C CB  . ASP A 1 340 ? 66.556  30.357 55.261  1.00 0.42 ? 340 ASP A CB  1 
ATOM 2580 C CG  . ASP A 1 340 ? 65.916  29.303 54.357  1.00 0.42 ? 340 ASP A CG  1 
ATOM 2581 O OD1 . ASP A 1 340 ? 65.883  28.100 54.724  1.00 0.42 ? 340 ASP A OD1 1 
ATOM 2582 O OD2 . ASP A 1 340 ? 65.481  29.698 53.245  1.00 0.42 ? 340 ASP A OD2 1 
ATOM 2583 N N   . ASP A 1 341 ? 67.759  27.524 56.931  1.00 0.46 ? 341 ASP A N   1 
ATOM 2584 C CA  . ASP A 1 341 ? 68.591  26.343 56.819  1.00 0.46 ? 341 ASP A CA  1 
ATOM 2585 C C   . ASP A 1 341 ? 69.018  26.021 55.384  1.00 0.46 ? 341 ASP A C   1 
ATOM 2586 O O   . ASP A 1 341 ? 70.005  25.324 55.152  1.00 0.46 ? 341 ASP A O   1 
ATOM 2587 C CB  . ASP A 1 341 ? 67.868  25.081 57.377  1.00 0.46 ? 341 ASP A CB  1 
ATOM 2588 C CG  . ASP A 1 341 ? 67.269  25.272 58.764  1.00 0.46 ? 341 ASP A CG  1 
ATOM 2589 O OD1 . ASP A 1 341 ? 66.382  26.151 58.900  1.00 0.46 ? 341 ASP A OD1 1 
ATOM 2590 O OD2 . ASP A 1 341 ? 67.630  24.471 59.663  1.00 0.46 ? 341 ASP A OD2 1 
ATOM 2591 N N   . LYS A 1 342 ? 68.259  26.500 54.375  1.00 0.47 ? 342 LYS A N   1 
ATOM 2592 C CA  . LYS A 1 342 ? 68.542  26.242 52.975  1.00 0.47 ? 342 LYS A CA  1 
ATOM 2593 C C   . LYS A 1 342 ? 69.507  27.256 52.367  1.00 0.47 ? 342 LYS A C   1 
ATOM 2594 O O   . LYS A 1 342 ? 69.992  27.051 51.254  1.00 0.47 ? 342 LYS A O   1 
ATOM 2595 C CB  . LYS A 1 342 ? 67.233  26.231 52.138  1.00 0.47 ? 342 LYS A CB  1 
ATOM 2596 C CG  . LYS A 1 342 ? 66.466  24.893 52.129  1.00 0.47 ? 342 LYS A CG  1 
ATOM 2597 C CD  . LYS A 1 342 ? 65.896  24.460 53.489  1.00 0.47 ? 342 LYS A CD  1 
ATOM 2598 C CE  . LYS A 1 342 ? 64.992  23.232 53.367  1.00 0.47 ? 342 LYS A CE  1 
ATOM 2599 N NZ  . LYS A 1 342 ? 64.465  22.854 54.694  1.00 0.47 ? 342 LYS A NZ  1 
ATOM 2600 N N   . ASP A 1 343 ? 69.839  28.362 53.071  1.00 0.53 ? 343 ASP A N   1 
ATOM 2601 C CA  . ASP A 1 343 ? 70.835  29.324 52.630  1.00 0.53 ? 343 ASP A CA  1 
ATOM 2602 C C   . ASP A 1 343 ? 72.240  28.680 52.556  1.00 0.53 ? 343 ASP A C   1 
ATOM 2603 O O   . ASP A 1 343 ? 72.656  28.053 53.533  1.00 0.53 ? 343 ASP A O   1 
ATOM 2604 C CB  . ASP A 1 343 ? 70.765  30.559 53.586  1.00 0.53 ? 343 ASP A CB  1 
ATOM 2605 C CG  . ASP A 1 343 ? 71.704  31.722 53.301  1.00 0.53 ? 343 ASP A CG  1 
ATOM 2606 O OD1 . ASP A 1 343 ? 72.654  31.572 52.491  1.00 0.53 ? 343 ASP A OD1 1 
ATOM 2607 O OD2 . ASP A 1 343 ? 71.526  32.778 53.952  1.00 0.53 ? 343 ASP A OD2 1 
ATOM 2608 N N   . PRO A 1 344 ? 73.048  28.785 51.491  1.00 0.54 ? 344 PRO A N   1 
ATOM 2609 C CA  . PRO A 1 344 ? 74.417  28.269 51.455  1.00 0.54 ? 344 PRO A CA  1 
ATOM 2610 C C   . PRO A 1 344 ? 75.331  28.869 52.518  1.00 0.54 ? 344 PRO A C   1 
ATOM 2611 O O   . PRO A 1 344 ? 76.316  28.229 52.888  1.00 0.54 ? 344 PRO A O   1 
ATOM 2612 C CB  . PRO A 1 344 ? 74.889  28.540 50.015  1.00 0.54 ? 344 PRO A CB  1 
ATOM 2613 C CG  . PRO A 1 344 ? 73.999  29.687 49.530  1.00 0.54 ? 344 PRO A CG  1 
ATOM 2614 C CD  . PRO A 1 344 ? 72.670  29.410 50.225  1.00 0.54 ? 344 PRO A CD  1 
ATOM 2615 N N   . ASN A 1 345 ? 75.027  30.081 53.032  1.00 0.60 ? 345 ASN A N   1 
ATOM 2616 C CA  . ASN A 1 345 ? 75.786  30.731 54.084  1.00 0.60 ? 345 ASN A CA  1 
ATOM 2617 C C   . ASN A 1 345 ? 75.494  30.129 55.461  1.00 0.60 ? 345 ASN A C   1 
ATOM 2618 O O   . ASN A 1 345 ? 76.282  30.258 56.395  1.00 0.60 ? 345 ASN A O   1 
ATOM 2619 C CB  . ASN A 1 345 ? 75.471  32.246 54.149  1.00 0.60 ? 345 ASN A CB  1 
ATOM 2620 C CG  . ASN A 1 345 ? 75.836  32.936 52.839  1.00 0.60 ? 345 ASN A CG  1 
ATOM 2621 O OD1 . ASN A 1 345 ? 76.975  33.358 52.633  1.00 0.60 ? 345 ASN A OD1 1 
ATOM 2622 N ND2 . ASN A 1 345 ? 74.850  33.086 51.929  1.00 0.60 ? 345 ASN A ND2 1 
ATOM 2623 N N   . PHE A 1 346 ? 74.357  29.406 55.617  1.00 0.51 ? 346 PHE A N   1 
ATOM 2624 C CA  . PHE A 1 346 ? 73.928  28.787 56.865  1.00 0.51 ? 346 PHE A CA  1 
ATOM 2625 C C   . PHE A 1 346 ? 74.918  27.755 57.378  1.00 0.51 ? 346 PHE A C   1 
ATOM 2626 O O   . PHE A 1 346 ? 75.148  27.649 58.576  1.00 0.51 ? 346 PHE A O   1 
ATOM 2627 C CB  . PHE A 1 346 ? 72.509  28.177 56.732  1.00 0.51 ? 346 PHE A CB  1 
ATOM 2628 C CG  . PHE A 1 346 ? 71.954  27.686 58.044  1.00 0.51 ? 346 PHE A CG  1 
ATOM 2629 C CD1 . PHE A 1 346 ? 71.387  28.582 58.962  1.00 0.51 ? 346 PHE A CD1 1 
ATOM 2630 C CD2 . PHE A 1 346 ? 71.965  26.315 58.351  1.00 0.51 ? 346 PHE A CD2 1 
ATOM 2631 C CE1 . PHE A 1 346 ? 70.814  28.117 60.152  1.00 0.51 ? 346 PHE A CE1 1 
ATOM 2632 C CE2 . PHE A 1 346 ? 71.391  25.846 59.538  1.00 0.51 ? 346 PHE A CE2 1 
ATOM 2633 C CZ  . PHE A 1 346 ? 70.808  26.748 60.436  1.00 0.51 ? 346 PHE A CZ  1 
ATOM 2634 N N   . LYS A 1 347 ? 75.575  27.020 56.460  1.00 0.51 ? 347 LYS A N   1 
ATOM 2635 C CA  . LYS A 1 347 ? 76.625  26.057 56.744  1.00 0.51 ? 347 LYS A CA  1 
ATOM 2636 C C   . LYS A 1 347 ? 77.773  26.638 57.571  1.00 0.51 ? 347 LYS A C   1 
ATOM 2637 O O   . LYS A 1 347 ? 78.308  25.972 58.455  1.00 0.51 ? 347 LYS A O   1 
ATOM 2638 C CB  . LYS A 1 347 ? 77.114  25.485 55.384  1.00 0.51 ? 347 LYS A CB  1 
ATOM 2639 C CG  . LYS A 1 347 ? 78.256  24.446 55.421  1.00 0.51 ? 347 LYS A CG  1 
ATOM 2640 C CD  . LYS A 1 347 ? 79.687  25.028 55.347  1.00 0.51 ? 347 LYS A CD  1 
ATOM 2641 C CE  . LYS A 1 347 ? 80.006  25.769 54.041  1.00 0.51 ? 347 LYS A CE  1 
ATOM 2642 N NZ  . LYS A 1 347 ? 81.300  26.467 54.157  1.00 0.51 ? 347 LYS A NZ  1 
ATOM 2643 N N   . ASP A 1 348 ? 78.167  27.906 57.320  1.00 0.55 ? 348 ASP A N   1 
ATOM 2644 C CA  . ASP A 1 348 ? 79.110  28.609 58.167  1.00 0.55 ? 348 ASP A CA  1 
ATOM 2645 C C   . ASP A 1 348 ? 78.415  29.197 59.398  1.00 0.55 ? 348 ASP A C   1 
ATOM 2646 O O   . ASP A 1 348 ? 78.846  29.000 60.534  1.00 0.55 ? 348 ASP A O   1 
ATOM 2647 C CB  . ASP A 1 348 ? 79.784  29.769 57.384  1.00 0.55 ? 348 ASP A CB  1 
ATOM 2648 C CG  . ASP A 1 348 ? 80.738  29.312 56.296  1.00 0.55 ? 348 ASP A CG  1 
ATOM 2649 O OD1 . ASP A 1 348 ? 80.901  28.080 56.102  1.00 0.55 ? 348 ASP A OD1 1 
ATOM 2650 O OD2 . ASP A 1 348 ? 81.345  30.191 55.632  1.00 0.55 ? 348 ASP A OD2 1 
ATOM 2651 N N   . GLN A 1 349 ? 77.280  29.909 59.213  1.00 0.64 ? 349 GLN A N   1 
ATOM 2652 C CA  . GLN A 1 349 ? 76.608  30.653 60.273  1.00 0.64 ? 349 GLN A CA  1 
ATOM 2653 C C   . GLN A 1 349 ? 76.123  29.821 61.442  1.00 0.64 ? 349 GLN A C   1 
ATOM 2654 O O   . GLN A 1 349 ? 76.201  30.261 62.586  1.00 0.64 ? 349 GLN A O   1 
ATOM 2655 C CB  . GLN A 1 349 ? 75.439  31.531 59.752  1.00 0.64 ? 349 GLN A CB  1 
ATOM 2656 C CG  . GLN A 1 349 ? 75.869  32.638 58.757  1.00 0.64 ? 349 GLN A CG  1 
ATOM 2657 C CD  . GLN A 1 349 ? 76.607  33.806 59.424  1.00 0.64 ? 349 GLN A CD  1 
ATOM 2658 O OE1 . GLN A 1 349 ? 77.505  33.648 60.248  1.00 0.64 ? 349 GLN A OE1 1 
ATOM 2659 N NE2 . GLN A 1 349 ? 76.205  35.047 59.067  1.00 0.64 ? 349 GLN A NE2 1 
ATOM 2660 N N   . VAL A 1 350 ? 75.654  28.586 61.196  1.00 0.57 ? 350 VAL A N   1 
ATOM 2661 C CA  . VAL A 1 350 ? 75.187  27.666 62.216  1.00 0.57 ? 350 VAL A CA  1 
ATOM 2662 C C   . VAL A 1 350 ? 76.255  27.298 63.256  1.00 0.57 ? 350 VAL A C   1 
ATOM 2663 O O   . VAL A 1 350 ? 75.914  27.038 64.403  1.00 0.57 ? 350 VAL A O   1 
ATOM 2664 C CB  . VAL A 1 350 ? 74.474  26.471 61.577  1.00 0.57 ? 350 VAL A CB  1 
ATOM 2665 C CG1 . VAL A 1 350 ? 75.455  25.441 60.982  1.00 0.57 ? 350 VAL A CG1 1 
ATOM 2666 C CG2 . VAL A 1 350 ? 73.486  25.827 62.571  1.00 0.57 ? 350 VAL A CG2 1 
ATOM 2667 N N   . ILE A 1 351 ? 77.570  27.363 62.905  1.00 0.58 ? 351 ILE A N   1 
ATOM 2668 C CA  . ILE A 1 351 ? 78.658  27.190 63.865  1.00 0.58 ? 351 ILE A CA  1 
ATOM 2669 C C   . ILE A 1 351 ? 79.355  28.505 64.222  1.00 0.58 ? 351 ILE A C   1 
ATOM 2670 O O   . ILE A 1 351 ? 79.914  28.658 65.311  1.00 0.58 ? 351 ILE A O   1 
ATOM 2671 C CB  . ILE A 1 351 ? 79.729  26.208 63.385  1.00 0.58 ? 351 ILE A CB  1 
ATOM 2672 C CG1 . ILE A 1 351 ? 80.290  26.531 61.977  1.00 0.58 ? 351 ILE A CG1 1 
ATOM 2673 C CG2 . ILE A 1 351 ? 79.106  24.798 63.456  1.00 0.58 ? 351 ILE A CG2 1 
ATOM 2674 C CD1 . ILE A 1 351 ? 81.485  25.662 61.572  1.00 0.58 ? 351 ILE A CD1 1 
ATOM 2675 N N   . LEU A 1 352 ? 79.334  29.523 63.331  1.00 0.63 ? 352 LEU A N   1 
ATOM 2676 C CA  . LEU A 1 352 ? 79.850  30.862 63.589  1.00 0.63 ? 352 LEU A CA  1 
ATOM 2677 C C   . LEU A 1 352 ? 79.059  31.591 64.672  1.00 0.63 ? 352 LEU A C   1 
ATOM 2678 O O   . LEU A 1 352 ? 79.620  32.325 65.479  1.00 0.63 ? 352 LEU A O   1 
ATOM 2679 C CB  . LEU A 1 352 ? 80.007  31.706 62.292  1.00 0.63 ? 352 LEU A CB  1 
ATOM 2680 C CG  . LEU A 1 352 ? 81.414  31.664 61.640  1.00 0.63 ? 352 LEU A CG  1 
ATOM 2681 C CD1 . LEU A 1 352 ? 81.862  30.256 61.208  1.00 0.63 ? 352 LEU A CD1 1 
ATOM 2682 C CD2 . LEU A 1 352 ? 81.463  32.613 60.430  1.00 0.63 ? 352 LEU A CD2 1 
ATOM 2683 N N   . LEU A 1 353 ? 77.739  31.357 64.792  1.00 0.61 ? 353 LEU A N   1 
ATOM 2684 C CA  . LEU A 1 353 ? 76.954  31.891 65.896  1.00 0.61 ? 353 LEU A CA  1 
ATOM 2685 C C   . LEU A 1 353 ? 77.466  31.500 67.282  1.00 0.61 ? 353 LEU A C   1 
ATOM 2686 O O   . LEU A 1 353 ? 77.637  32.342 68.167  1.00 0.61 ? 353 LEU A O   1 
ATOM 2687 C CB  . LEU A 1 353 ? 75.507  31.368 65.772  1.00 0.61 ? 353 LEU A CB  1 
ATOM 2688 C CG  . LEU A 1 353 ? 74.655  32.085 64.707  1.00 0.61 ? 353 LEU A CG  1 
ATOM 2689 C CD1 . LEU A 1 353 ? 73.478  31.202 64.269  1.00 0.61 ? 353 LEU A CD1 1 
ATOM 2690 C CD2 . LEU A 1 353 ? 74.134  33.436 65.218  1.00 0.61 ? 353 LEU A CD2 1 
ATOM 2691 N N   . ASN A 1 354 ? 77.775  30.211 67.497  1.00 0.60 ? 354 ASN A N   1 
ATOM 2692 C CA  . ASN A 1 354 ? 78.280  29.688 68.755  1.00 0.60 ? 354 ASN A CA  1 
ATOM 2693 C C   . ASN A 1 354 ? 79.666  30.148 69.112  1.00 0.60 ? 354 ASN A C   1 
ATOM 2694 O O   . ASN A 1 354 ? 80.003  30.288 70.281  1.00 0.60 ? 354 ASN A O   1 
ATOM 2695 C CB  . ASN A 1 354 ? 78.231  28.156 68.754  1.00 0.60 ? 354 ASN A CB  1 
ATOM 2696 C CG  . ASN A 1 354 ? 76.761  27.792 68.543  1.00 0.60 ? 354 ASN A CG  1 
ATOM 2697 O OD1 . ASN A 1 354 ? 76.260  27.774 67.422  1.00 0.60 ? 354 ASN A OD1 1 
ATOM 2698 N ND2 . ASN A 1 354 ? 75.981  27.689 69.643  1.00 0.60 ? 354 ASN A ND2 1 
ATOM 2699 N N   . LYS A 1 355 ? 80.498  30.420 68.099  1.00 0.59 ? 355 LYS A N   1 
ATOM 2700 C CA  . LYS A 1 355 ? 81.807  30.998 68.303  1.00 0.59 ? 355 LYS A CA  1 
ATOM 2701 C C   . LYS A 1 355 ? 81.798  32.463 68.733  1.00 0.59 ? 355 LYS A C   1 
ATOM 2702 O O   . LYS A 1 355 ? 82.765  32.925 69.333  1.00 0.59 ? 355 LYS A O   1 
ATOM 2703 C CB  . LYS A 1 355 ? 82.634  30.880 67.002  1.00 0.59 ? 355 LYS A CB  1 
ATOM 2704 C CG  . LYS A 1 355 ? 83.083  29.442 66.698  1.00 0.59 ? 355 LYS A CG  1 
ATOM 2705 C CD  . LYS A 1 355 ? 83.801  29.334 65.342  1.00 0.59 ? 355 LYS A CD  1 
ATOM 2706 C CE  . LYS A 1 355 ? 84.403  27.955 65.051  1.00 0.59 ? 355 LYS A CE  1 
ATOM 2707 N NZ  . LYS A 1 355 ? 85.685  27.800 65.777  1.00 0.59 ? 355 LYS A NZ  1 
ATOM 2708 N N   . HIS A 1 356 ? 80.729  33.238 68.441  1.00 0.65 ? 356 HIS A N   1 
ATOM 2709 C CA  . HIS A 1 356 ? 80.804  34.685 68.553  1.00 0.65 ? 356 HIS A CA  1 
ATOM 2710 C C   . HIS A 1 356 ? 79.716  35.365 69.386  1.00 0.65 ? 356 HIS A C   1 
ATOM 2711 O O   . HIS A 1 356 ? 79.912  36.509 69.802  1.00 0.65 ? 356 HIS A O   1 
ATOM 2712 C CB  . HIS A 1 356 ? 80.859  35.301 67.141  1.00 0.65 ? 356 HIS A CB  1 
ATOM 2713 C CG  . HIS A 1 356 ? 82.117  34.918 66.412  1.00 0.65 ? 356 HIS A CG  1 
ATOM 2714 N ND1 . HIS A 1 356 ? 82.040  34.140 65.278  1.00 0.65 ? 356 HIS A ND1 1 
ATOM 2715 C CD2 . HIS A 1 356 ? 83.417  35.199 66.695  1.00 0.65 ? 356 HIS A CD2 1 
ATOM 2716 C CE1 . HIS A 1 356 ? 83.285  33.950 64.897  1.00 0.65 ? 356 HIS A CE1 1 
ATOM 2717 N NE2 . HIS A 1 356 ? 84.162  34.569 65.721  1.00 0.65 ? 356 HIS A NE2 1 
ATOM 2718 N N   . ILE A 1 357 ? 78.568  34.716 69.685  1.00 0.62 ? 357 ILE A N   1 
ATOM 2719 C CA  . ILE A 1 357 ? 77.577  35.187 70.663  1.00 0.62 ? 357 ILE A CA  1 
ATOM 2720 C C   . ILE A 1 357 ? 78.077  35.057 72.108  1.00 0.62 ? 357 ILE A C   1 
ATOM 2721 O O   . ILE A 1 357 ? 78.550  33.999 72.509  1.00 0.62 ? 357 ILE A O   1 
ATOM 2722 C CB  . ILE A 1 357 ? 76.228  34.474 70.483  1.00 0.62 ? 357 ILE A CB  1 
ATOM 2723 C CG1 . ILE A 1 357 ? 75.560  34.947 69.170  1.00 0.62 ? 357 ILE A CG1 1 
ATOM 2724 C CG2 . ILE A 1 357 ? 75.274  34.693 71.685  1.00 0.62 ? 357 ILE A CG2 1 
ATOM 2725 C CD1 . ILE A 1 357 ? 74.330  34.132 68.753  1.00 0.62 ? 357 ILE A CD1 1 
ATOM 2726 N N   . ASP A 1 358 ? 78.017  36.158 72.911  1.00 0.61 ? 358 ASP A N   1 
ATOM 2727 C CA  . ASP A 1 358 ? 78.404  36.240 74.327  1.00 0.61 ? 358 ASP A CA  1 
ATOM 2728 C C   . ASP A 1 358 ? 79.891  35.906 74.549  1.00 0.61 ? 358 ASP A C   1 
ATOM 2729 O O   . ASP A 1 358 ? 80.374  35.607 75.639  1.00 0.61 ? 358 ASP A O   1 
ATOM 2730 C CB  . ASP A 1 358 ? 77.430  35.437 75.251  1.00 0.61 ? 358 ASP A CB  1 
ATOM 2731 C CG  . ASP A 1 358 ? 77.489  35.798 76.732  1.00 0.61 ? 358 ASP A CG  1 
ATOM 2732 O OD1 . ASP A 1 358 ? 77.945  36.909 77.099  1.00 0.61 ? 358 ASP A OD1 1 
ATOM 2733 O OD2 . ASP A 1 358 ? 77.034  34.948 77.551  1.00 0.61 ? 358 ASP A OD2 1 
ATOM 2734 N N   . ALA A 1 359 ? 80.706  35.988 73.478  1.00 0.69 ? 359 ALA A N   1 
ATOM 2735 C CA  . ALA A 1 359 ? 81.978  35.299 73.434  1.00 0.69 ? 359 ALA A CA  1 
ATOM 2736 C C   . ALA A 1 359 ? 83.098  35.897 74.277  1.00 0.69 ? 359 ALA A C   1 
ATOM 2737 O O   . ALA A 1 359 ? 84.077  35.231 74.585  1.00 0.69 ? 359 ALA A O   1 
ATOM 2738 C CB  . ALA A 1 359 ? 82.400  35.153 71.962  1.00 0.69 ? 359 ALA A CB  1 
ATOM 2739 N N   . TYR A 1 360 ? 82.946  37.151 74.737  1.00 0.54 ? 360 TYR A N   1 
ATOM 2740 C CA  . TYR A 1 360 ? 83.846  37.817 75.664  1.00 0.54 ? 360 TYR A CA  1 
ATOM 2741 C C   . TYR A 1 360 ? 83.831  37.194 77.073  1.00 0.54 ? 360 TYR A C   1 
ATOM 2742 O O   . TYR A 1 360 ? 84.774  37.334 77.853  1.00 0.54 ? 360 TYR A O   1 
ATOM 2743 C CB  . TYR A 1 360 ? 83.420  39.312 75.729  1.00 0.54 ? 360 TYR A CB  1 
ATOM 2744 C CG  . TYR A 1 360 ? 84.246  40.121 76.683  1.00 0.54 ? 360 TYR A CG  1 
ATOM 2745 C CD1 . TYR A 1 360 ? 85.618  40.327 76.465  1.00 0.54 ? 360 TYR A CD1 1 
ATOM 2746 C CD2 . TYR A 1 360 ? 83.655  40.621 77.852  1.00 0.54 ? 360 TYR A CD2 1 
ATOM 2747 C CE1 . TYR A 1 360 ? 86.388  41.027 77.405  1.00 0.54 ? 360 TYR A CE1 1 
ATOM 2748 C CE2 . TYR A 1 360 ? 84.420  41.327 78.781  1.00 0.54 ? 360 TYR A CE2 1 
ATOM 2749 C CZ  . TYR A 1 360 ? 85.782  41.520 78.560  1.00 0.54 ? 360 TYR A CZ  1 
ATOM 2750 O OH  . TYR A 1 360 ? 86.493  42.227 79.537  1.00 0.54 ? 360 TYR A OH  1 
ATOM 2751 N N   . LYS A 1 361 ? 82.750  36.481 77.442  1.00 0.55 ? 361 LYS A N   1 
ATOM 2752 C CA  . LYS A 1 361 ? 82.591  35.852 78.742  1.00 0.55 ? 361 LYS A CA  1 
ATOM 2753 C C   . LYS A 1 361 ? 83.628  34.789 79.082  1.00 0.55 ? 361 LYS A C   1 
ATOM 2754 O O   . LYS A 1 361 ? 83.892  34.543 80.253  1.00 0.55 ? 361 LYS A O   1 
ATOM 2755 C CB  . LYS A 1 361 ? 81.176  35.247 78.845  1.00 0.55 ? 361 LYS A CB  1 
ATOM 2756 C CG  . LYS A 1 361 ? 80.841  34.597 80.200  1.00 0.55 ? 361 LYS A CG  1 
ATOM 2757 C CD  . LYS A 1 361 ? 79.381  34.133 80.255  1.00 0.55 ? 361 LYS A CD  1 
ATOM 2758 C CE  . LYS A 1 361 ? 78.409  35.294 80.467  1.00 0.55 ? 361 LYS A CE  1 
ATOM 2759 N NZ  . LYS A 1 361 ? 77.039  34.875 80.134  1.00 0.55 ? 361 LYS A NZ  1 
ATOM 2760 N N   . THR A 1 362 ? 84.267  34.158 78.083  1.00 0.52 ? 362 THR A N   1 
ATOM 2761 C CA  . THR A 1 362 ? 85.244  33.110 78.322  1.00 0.52 ? 362 THR A CA  1 
ATOM 2762 C C   . THR A 1 362 ? 86.682  33.614 78.350  1.00 0.52 ? 362 THR A C   1 
ATOM 2763 O O   . THR A 1 362 ? 87.634  32.836 78.367  1.00 0.52 ? 362 THR A O   1 
ATOM 2764 C CB  . THR A 1 362 ? 85.119  31.979 77.323  1.00 0.52 ? 362 THR A CB  1 
ATOM 2765 O OG1 . THR A 1 362 ? 85.145  32.413 75.979  1.00 0.52 ? 362 THR A OG1 1 
ATOM 2766 C CG2 . THR A 1 362 ? 83.763  31.273 77.458  1.00 0.52 ? 362 THR A CG2 1 
ATOM 2767 N N   . PHE A 1 363 ? 86.897  34.948 78.394  1.00 0.45 ? 363 PHE A N   1 
ATOM 2768 C CA  . PHE A 1 363 ? 88.196  35.553 78.656  1.00 0.45 ? 363 PHE A CA  1 
ATOM 2769 C C   . PHE A 1 363 ? 88.691  35.233 80.092  1.00 0.45 ? 363 PHE A C   1 
ATOM 2770 O O   . PHE A 1 363 ? 87.860  35.153 80.993  1.00 0.45 ? 363 PHE A O   1 
ATOM 2771 C CB  . PHE A 1 363 ? 88.105  37.095 78.382  1.00 0.45 ? 363 PHE A CB  1 
ATOM 2772 C CG  . PHE A 1 363 ? 89.420  37.790 78.135  1.00 0.45 ? 363 PHE A CG  1 
ATOM 2773 C CD1 . PHE A 1 363 ? 90.330  37.278 77.200  1.00 0.45 ? 363 PHE A CD1 1 
ATOM 2774 C CD2 . PHE A 1 363 ? 89.750  38.982 78.807  1.00 0.45 ? 363 PHE A CD2 1 
ATOM 2775 C CE1 . PHE A 1 363 ? 91.578  37.882 77.011  1.00 0.45 ? 363 PHE A CE1 1 
ATOM 2776 C CE2 . PHE A 1 363 ? 91.000  39.587 78.626  1.00 0.45 ? 363 PHE A CE2 1 
ATOM 2777 C CZ  . PHE A 1 363 ? 91.921  39.027 77.735  1.00 0.45 ? 363 PHE A CZ  1 
ATOM 2778 N N   . PRO A 1 364 ? 89.970  35.051 80.446  1.00 0.34 ? 364 PRO A N   1 
ATOM 2779 C CA  . PRO A 1 364 ? 90.388  34.679 81.808  1.00 0.34 ? 364 PRO A CA  1 
ATOM 2780 C C   . PRO A 1 364 ? 89.932  35.559 82.982  1.00 0.34 ? 364 PRO A C   1 
ATOM 2781 O O   . PRO A 1 364 ? 89.796  34.979 84.057  1.00 0.34 ? 364 PRO A O   1 
ATOM 2782 C CB  . PRO A 1 364 ? 91.924  34.593 81.728  1.00 0.34 ? 364 PRO A CB  1 
ATOM 2783 C CG  . PRO A 1 364 ? 92.228  34.360 80.245  1.00 0.34 ? 364 PRO A CG  1 
ATOM 2784 C CD  . PRO A 1 364 ? 91.101  35.097 79.527  1.00 0.34 ? 364 PRO A CD  1 
ATOM 2785 N N   . PRO A 1 365 ? 89.715  36.877 82.931  1.00 0.43 ? 365 PRO A N   1 
ATOM 2786 C CA  . PRO A 1 365 ? 89.123  37.621 84.037  1.00 0.43 ? 365 PRO A CA  1 
ATOM 2787 C C   . PRO A 1 365 ? 87.618  37.446 84.178  1.00 0.43 ? 365 PRO A C   1 
ATOM 2788 O O   . PRO A 1 365 ? 87.070  37.952 85.154  1.00 0.43 ? 365 PRO A O   1 
ATOM 2789 C CB  . PRO A 1 365 ? 89.397  39.100 83.679  1.00 0.43 ? 365 PRO A CB  1 
ATOM 2790 C CG  . PRO A 1 365 ? 90.559  39.061 82.691  1.00 0.43 ? 365 PRO A CG  1 
ATOM 2791 C CD  . PRO A 1 365 ? 90.295  37.767 81.937  1.00 0.43 ? 365 PRO A CD  1 
ATOM 2792 N N   . THR A 1 366 ? 86.907  36.861 83.194  1.00 0.29 ? 366 THR A N   1 
ATOM 2793 C CA  . THR A 1 366 ? 85.453  36.948 83.124  1.00 0.29 ? 366 THR A CA  1 
ATOM 2794 C C   . THR A 1 366 ? 84.745  35.641 83.443  1.00 0.29 ? 366 THR A C   1 
ATOM 2795 O O   . THR A 1 366 ? 83.523  35.649 83.608  1.00 0.29 ? 366 THR A O   1 
ATOM 2796 C CB  . THR A 1 366 ? 84.965  37.505 81.782  1.00 0.29 ? 366 THR A CB  1 
ATOM 2797 O OG1 . THR A 1 366 ? 85.637  36.917 80.687  1.00 0.29 ? 366 THR A OG1 1 
ATOM 2798 C CG2 . THR A 1 366 ? 85.320  38.997 81.681  1.00 0.29 ? 366 THR A CG2 1 
ATOM 2799 N N   . GLU A 1 367 ? 85.468  34.516 83.657  1.00 0.55 ? 367 GLU A N   1 
ATOM 2800 C CA  . GLU A 1 367 ? 84.875  33.288 84.158  1.00 0.55 ? 367 GLU A CA  1 
ATOM 2801 C C   . GLU A 1 367 ? 85.846  32.542 85.077  1.00 0.55 ? 367 GLU A C   1 
ATOM 2802 O O   . GLU A 1 367 ? 87.037  32.841 85.045  1.00 0.55 ? 367 GLU A O   1 
ATOM 2803 C CB  . GLU A 1 367 ? 84.358  32.357 83.023  1.00 0.55 ? 367 GLU A CB  1 
ATOM 2804 C CG  . GLU A 1 367 ? 85.425  31.744 82.077  1.00 0.55 ? 367 GLU A CG  1 
ATOM 2805 C CD  . GLU A 1 367 ? 84.836  30.680 81.140  1.00 0.55 ? 367 GLU A CD  1 
ATOM 2806 O OE1 . GLU A 1 367 ? 83.646  30.302 81.314  1.00 0.55 ? 367 GLU A OE1 1 
ATOM 2807 O OE2 . GLU A 1 367 ? 85.588  30.182 80.260  1.00 0.55 ? 367 GLU A OE2 1 
ATOM 2808 N N   . PRO A 1 368 ? 85.450  31.592 85.948  1.00 0.47 ? 368 PRO A N   1 
ATOM 2809 C CA  . PRO A 1 368 ? 86.360  31.044 86.960  1.00 0.47 ? 368 PRO A CA  1 
ATOM 2810 C C   . PRO A 1 368 ? 87.377  30.053 86.425  1.00 0.47 ? 368 PRO A C   1 
ATOM 2811 O O   . PRO A 1 368 ? 88.335  29.730 87.127  1.00 0.47 ? 368 PRO A O   1 
ATOM 2812 C CB  . PRO A 1 368 ? 85.430  30.304 87.946  1.00 0.47 ? 368 PRO A CB  1 
ATOM 2813 C CG  . PRO A 1 368 ? 84.059  30.949 87.752  1.00 0.47 ? 368 PRO A CG  1 
ATOM 2814 C CD  . PRO A 1 368 ? 84.051  31.290 86.264  1.00 0.47 ? 368 PRO A CD  1 
ATOM 2815 N N   . LYS A 1 369 ? 87.125  29.455 85.250  1.00 0.52 ? 369 LYS A N   1 
ATOM 2816 C CA  . LYS A 1 369 ? 87.940  28.385 84.713  1.00 0.52 ? 369 LYS A CA  1 
ATOM 2817 C C   . LYS A 1 369 ? 89.314  28.801 84.210  1.00 0.52 ? 369 LYS A C   1 
ATOM 2818 O O   . LYS A 1 369 ? 89.490  29.754 83.459  1.00 0.52 ? 369 LYS A O   1 
ATOM 2819 C CB  . LYS A 1 369 ? 87.189  27.609 83.605  1.00 0.52 ? 369 LYS A CB  1 
ATOM 2820 C CG  . LYS A 1 369 ? 85.924  26.916 84.137  1.00 0.52 ? 369 LYS A CG  1 
ATOM 2821 C CD  . LYS A 1 369 ? 85.189  26.104 83.060  1.00 0.52 ? 369 LYS A CD  1 
ATOM 2822 C CE  . LYS A 1 369 ? 83.937  25.415 83.609  1.00 0.52 ? 369 LYS A CE  1 
ATOM 2823 N NZ  . LYS A 1 369 ? 83.264  24.634 82.547  1.00 0.52 ? 369 LYS A NZ  1 
ATOM 2824 N N   . LYS A 1 370 ? 90.351  28.034 84.599  1.00 0.53 ? 370 LYS A N   1 
ATOM 2825 C CA  . LYS A 1 370 ? 91.682  28.187 84.057  1.00 0.53 ? 370 LYS A CA  1 
ATOM 2826 C C   . LYS A 1 370 ? 91.829  27.562 82.677  1.00 0.53 ? 370 LYS A C   1 
ATOM 2827 O O   . LYS A 1 370 ? 91.040  26.700 82.290  1.00 0.53 ? 370 LYS A O   1 
ATOM 2828 C CB  . LYS A 1 370 ? 92.732  27.555 85.005  1.00 0.53 ? 370 LYS A CB  1 
ATOM 2829 C CG  . LYS A 1 370 ? 92.656  26.017 85.123  1.00 0.53 ? 370 LYS A CG  1 
ATOM 2830 C CD  . LYS A 1 370 ? 93.644  25.430 86.150  1.00 0.53 ? 370 LYS A CD  1 
ATOM 2831 C CE  . LYS A 1 370 ? 95.117  25.674 85.791  1.00 0.53 ? 370 LYS A CE  1 
ATOM 2832 N NZ  . LYS A 1 370 ? 96.019  25.053 86.791  1.00 0.53 ? 370 LYS A NZ  1 
ATOM 2833 N N   . ASP A 1 371 ? 92.880  27.951 81.914  1.00 0.55 ? 371 ASP A N   1 
ATOM 2834 C CA  . ASP A 1 371 ? 93.214  27.327 80.650  1.00 0.55 ? 371 ASP A CA  1 
ATOM 2835 C C   . ASP A 1 371 ? 93.526  25.829 80.816  1.00 0.55 ? 371 ASP A C   1 
ATOM 2836 O O   . ASP A 1 371 ? 94.373  25.401 81.611  1.00 0.55 ? 371 ASP A O   1 
ATOM 2837 C CB  . ASP A 1 371 ? 94.346  28.130 79.948  1.00 0.55 ? 371 ASP A CB  1 
ATOM 2838 C CG  . ASP A 1 371 ? 94.686  27.577 78.570  1.00 0.55 ? 371 ASP A CG  1 
ATOM 2839 O OD1 . ASP A 1 371 ? 93.879  26.771 78.034  1.00 0.55 ? 371 ASP A OD1 1 
ATOM 2840 O OD2 . ASP A 1 371 ? 95.775  27.925 78.062  1.00 0.55 ? 371 ASP A OD2 1 
ATOM 2841 N N   . LYS A 1 372 ? 92.782  24.997 80.067  1.00 0.57 ? 372 LYS A N   1 
ATOM 2842 C CA  . LYS A 1 372 ? 92.962  23.572 80.015  1.00 0.57 ? 372 LYS A CA  1 
ATOM 2843 C C   . LYS A 1 372 ? 93.482  23.104 78.670  1.00 0.57 ? 372 LYS A C   1 
ATOM 2844 O O   . LYS A 1 372 ? 93.681  21.905 78.496  1.00 0.57 ? 372 LYS A O   1 
ATOM 2845 C CB  . LYS A 1 372 ? 91.611  22.865 80.289  1.00 0.57 ? 372 LYS A CB  1 
ATOM 2846 C CG  . LYS A 1 372 ? 91.002  23.144 81.676  1.00 0.57 ? 372 LYS A CG  1 
ATOM 2847 C CD  . LYS A 1 372 ? 91.850  22.644 82.859  1.00 0.57 ? 372 LYS A CD  1 
ATOM 2848 C CE  . LYS A 1 372 ? 92.029  21.123 82.854  1.00 0.57 ? 372 LYS A CE  1 
ATOM 2849 N NZ  . LYS A 1 372 ? 92.745  20.675 84.069  1.00 0.57 ? 372 LYS A NZ  1 
ATOM 2850 N N   . LYS A 1 373 ? 93.741  24.009 77.697  1.00 0.58 ? 373 LYS A N   1 
ATOM 2851 C CA  . LYS A 1 373 ? 94.149  23.637 76.352  1.00 0.58 ? 373 LYS A CA  1 
ATOM 2852 C C   . LYS A 1 373 ? 95.525  22.986 76.278  1.00 0.58 ? 373 LYS A C   1 
ATOM 2853 O O   . LYS A 1 373 ? 95.743  22.020 75.549  1.00 0.58 ? 373 LYS A O   1 
ATOM 2854 C CB  . LYS A 1 373 ? 94.122  24.886 75.436  1.00 0.58 ? 373 LYS A CB  1 
ATOM 2855 C CG  . LYS A 1 373 ? 94.189  24.580 73.930  1.00 0.58 ? 373 LYS A CG  1 
ATOM 2856 C CD  . LYS A 1 373 ? 94.356  25.863 73.096  1.00 0.58 ? 373 LYS A CD  1 
ATOM 2857 C CE  . LYS A 1 373 ? 94.503  25.624 71.591  1.00 0.58 ? 373 LYS A CE  1 
ATOM 2858 N NZ  . LYS A 1 373 ? 94.839  26.838 70.821  1.00 0.58 ? 373 LYS A NZ  1 
ATOM 2859 N N   . LYS A 1 374 ? 96.509  23.528 77.032  1.00 0.53 ? 374 LYS A N   1 
ATOM 2860 C CA  . LYS A 1 374 ? 97.868  23.005 77.156  1.00 0.53 ? 374 LYS A CA  1 
ATOM 2861 C C   . LYS A 1 374 ? 98.621  22.821 75.839  1.00 0.53 ? 374 LYS A C   1 
ATOM 2862 O O   . LYS A 1 374 ? 99.478  21.948 75.707  1.00 0.53 ? 374 LYS A O   1 
ATOM 2863 C CB  . LYS A 1 374 ? 97.919  21.706 78.007  1.00 0.53 ? 374 LYS A CB  1 
ATOM 2864 C CG  . LYS A 1 374 ? 97.404  21.903 79.442  1.00 0.53 ? 374 LYS A CG  1 
ATOM 2865 C CD  . LYS A 1 374 ? 97.465  20.627 80.305  1.00 0.53 ? 374 LYS A CD  1 
ATOM 2866 C CE  . LYS A 1 374 ? 98.894  20.141 80.584  1.00 0.53 ? 374 LYS A CE  1 
ATOM 2867 N NZ  . LYS A 1 374 ? 98.892  18.965 81.488  1.00 0.53 ? 374 LYS A NZ  1 
ATOM 2868 N N   . LYS A 1 375 ? 98.312  23.683 74.848  1.00 0.50 ? 375 LYS A N   1 
ATOM 2869 C CA  . LYS A 1 375 ? 98.807  23.641 73.483  1.00 0.50 ? 375 LYS A CA  1 
ATOM 2870 C C   . LYS A 1 375 ? 98.582  22.308 72.760  1.00 0.50 ? 375 LYS A C   1 
ATOM 2871 O O   . LYS A 1 375 ? 99.396  21.898 71.934  1.00 0.50 ? 375 LYS A O   1 
ATOM 2872 C CB  . LYS A 1 375 ? 100.290 24.088 73.392  1.00 0.50 ? 375 LYS A CB  1 
ATOM 2873 C CG  . LYS A 1 375 ? 100.532 25.504 73.942  1.00 0.50 ? 375 LYS A CG  1 
ATOM 2874 C CD  . LYS A 1 375 ? 102.006 25.946 73.888  1.00 0.50 ? 375 LYS A CD  1 
ATOM 2875 C CE  . LYS A 1 375 ? 102.537 26.102 72.462  1.00 0.50 ? 375 LYS A CE  1 
ATOM 2876 N NZ  . LYS A 1 375 ? 103.940 26.574 72.483  1.00 0.50 ? 375 LYS A NZ  1 
ATOM 2877 N N   . ALA A 1 376 ? 97.457  21.620 73.033  1.00 0.49 ? 376 ALA A N   1 
ATOM 2878 C CA  . ALA A 1 376 ? 97.214  20.284 72.546  1.00 0.49 ? 376 ALA A CA  1 
ATOM 2879 C C   . ALA A 1 376 ? 95.730  20.074 72.292  1.00 0.49 ? 376 ALA A C   1 
ATOM 2880 O O   . ALA A 1 376 ? 94.903  20.925 72.617  1.00 0.49 ? 376 ALA A O   1 
ATOM 2881 C CB  . ALA A 1 376 ? 97.717  19.277 73.597  1.00 0.49 ? 376 ALA A CB  1 
ATOM 2882 N N   . ASP A 1 377 ? 95.388  18.944 71.639  1.00 0.46 ? 377 ASP A N   1 
ATOM 2883 C CA  . ASP A 1 377 ? 94.041  18.447 71.391  1.00 0.46 ? 377 ASP A CA  1 
ATOM 2884 C C   . ASP A 1 377 ? 93.096  19.408 70.669  1.00 0.46 ? 377 ASP A C   1 
ATOM 2885 O O   . ASP A 1 377 ? 91.888  19.439 70.902  1.00 0.46 ? 377 ASP A O   1 
ATOM 2886 C CB  . ASP A 1 377 ? 93.418  17.862 72.683  1.00 0.46 ? 377 ASP A CB  1 
ATOM 2887 C CG  . ASP A 1 377 ? 94.282  16.749 73.262  1.00 0.46 ? 377 ASP A CG  1 
ATOM 2888 O OD1 . ASP A 1 377 ? 95.171  16.234 72.530  1.00 0.46 ? 377 ASP A OD1 1 
ATOM 2889 O OD2 . ASP A 1 377 ? 94.054  16.397 74.446  1.00 0.46 ? 377 ASP A OD2 1 
ATOM 2890 N N   . GLU A 1 378 ? 93.629  20.209 69.723  1.00 0.50 ? 378 GLU A N   1 
ATOM 2891 C CA  . GLU A 1 378 ? 92.854  21.114 68.901  1.00 0.50 ? 378 GLU A CA  1 
ATOM 2892 C C   . GLU A 1 378 ? 91.875  20.406 67.973  1.00 0.50 ? 378 GLU A C   1 
ATOM 2893 O O   . GLU A 1 378 ? 92.210  19.436 67.297  1.00 0.50 ? 378 GLU A O   1 
ATOM 2894 C CB  . GLU A 1 378 ? 93.781  22.062 68.098  1.00 0.50 ? 378 GLU A CB  1 
ATOM 2895 C CG  . GLU A 1 378 ? 94.656  22.954 69.013  1.00 0.50 ? 378 GLU A CG  1 
ATOM 2896 C CD  . GLU A 1 378 ? 95.420  24.044 68.259  1.00 0.50 ? 378 GLU A CD  1 
ATOM 2897 O OE1 . GLU A 1 378 ? 96.003  23.741 67.192  1.00 0.50 ? 378 GLU A OE1 1 
ATOM 2898 O OE2 . GLU A 1 378 ? 95.441  25.195 68.776  1.00 0.50 ? 378 GLU A OE2 1 
ATOM 2899 N N   . THR A 1 379 ? 90.618  20.897 67.901  1.00 0.49 ? 379 THR A N   1 
ATOM 2900 C CA  . THR A 1 379 ? 89.556  20.267 67.108  1.00 0.49 ? 379 THR A CA  1 
ATOM 2901 C C   . THR A 1 379 ? 89.777  20.303 65.607  1.00 0.49 ? 379 THR A C   1 
ATOM 2902 O O   . THR A 1 379 ? 89.299  19.439 64.879  1.00 0.49 ? 379 THR A O   1 
ATOM 2903 C CB  . THR A 1 379 ? 88.184  20.848 67.445  1.00 0.49 ? 379 THR A CB  1 
ATOM 2904 O OG1 . THR A 1 379 ? 87.907  20.594 68.810  1.00 0.49 ? 379 THR A OG1 1 
ATOM 2905 C CG2 . THR A 1 379 ? 87.006  20.217 66.689  1.00 0.49 ? 379 THR A CG2 1 
ATOM 2906 N N   . GLN A 1 380 ? 90.503  21.324 65.096  1.00 0.37 ? 380 GLN A N   1 
ATOM 2907 C CA  . GLN A 1 380 ? 90.787  21.513 63.677  1.00 0.37 ? 380 GLN A CA  1 
ATOM 2908 C C   . GLN A 1 380 ? 89.535  21.584 62.805  1.00 0.37 ? 380 GLN A C   1 
ATOM 2909 O O   . GLN A 1 380 ? 89.346  20.870 61.821  1.00 0.37 ? 380 GLN A O   1 
ATOM 2910 C CB  . GLN A 1 380 ? 91.863  20.518 63.166  1.00 0.37 ? 380 GLN A CB  1 
ATOM 2911 C CG  . GLN A 1 380 ? 92.490  20.832 61.783  1.00 0.37 ? 380 GLN A CG  1 
ATOM 2912 C CD  . GLN A 1 380 ? 93.291  22.133 61.761  1.00 0.37 ? 380 GLN A CD  1 
ATOM 2913 O OE1 . GLN A 1 380 ? 93.544  22.798 62.763  1.00 0.37 ? 380 GLN A OE1 1 
ATOM 2914 N NE2 . GLN A 1 380 ? 93.719  22.530 60.540  1.00 0.37 ? 380 GLN A NE2 1 
ATOM 2915 N N   . ALA A 1 381 ? 88.613  22.480 63.208  1.00 0.45 ? 381 ALA A N   1 
ATOM 2916 C CA  . ALA A 1 381 ? 87.328  22.686 62.582  1.00 0.45 ? 381 ALA A CA  1 
ATOM 2917 C C   . ALA A 1 381 ? 87.402  23.292 61.183  1.00 0.45 ? 381 ALA A C   1 
ATOM 2918 O O   . ALA A 1 381 ? 88.410  23.848 60.768  1.00 0.45 ? 381 ALA A O   1 
ATOM 2919 C CB  . ALA A 1 381 ? 86.446  23.554 63.509  1.00 0.45 ? 381 ALA A CB  1 
ATOM 2920 N N   . LEU A 1 382 ? 86.291  23.191 60.424  1.00 0.39 ? 382 LEU A N   1 
ATOM 2921 C CA  . LEU A 1 382 ? 86.193  23.624 59.037  1.00 0.39 ? 382 LEU A CA  1 
ATOM 2922 C C   . LEU A 1 382 ? 86.489  25.102 58.712  1.00 0.39 ? 382 LEU A C   1 
ATOM 2923 O O   . LEU A 1 382 ? 87.167  25.333 57.707  1.00 0.39 ? 382 LEU A O   1 
ATOM 2924 C CB  . LEU A 1 382 ? 84.781  23.228 58.518  1.00 0.39 ? 382 LEU A CB  1 
ATOM 2925 C CG  . LEU A 1 382 ? 84.486  23.501 57.026  1.00 0.39 ? 382 LEU A CG  1 
ATOM 2926 C CD1 . LEU A 1 382 ? 85.400  22.680 56.102  1.00 0.39 ? 382 LEU A CD1 1 
ATOM 2927 C CD2 . LEU A 1 382 ? 83.008  23.209 56.715  1.00 0.39 ? 382 LEU A CD2 1 
ATOM 2928 N N   . PRO A 1 383 ? 86.053  26.150 59.422  1.00 0.48 ? 383 PRO A N   1 
ATOM 2929 C CA  . PRO A 1 383 ? 86.336  27.515 58.998  1.00 0.48 ? 383 PRO A CA  1 
ATOM 2930 C C   . PRO A 1 383 ? 87.753  27.951 59.331  1.00 0.48 ? 383 PRO A C   1 
ATOM 2931 O O   . PRO A 1 383 ? 88.249  27.687 60.425  1.00 0.48 ? 383 PRO A O   1 
ATOM 2932 C CB  . PRO A 1 383 ? 85.297  28.372 59.742  1.00 0.48 ? 383 PRO A CB  1 
ATOM 2933 C CG  . PRO A 1 383 ? 84.936  27.544 60.974  1.00 0.48 ? 383 PRO A CG  1 
ATOM 2934 C CD  . PRO A 1 383 ? 85.032  26.108 60.463  1.00 0.48 ? 383 PRO A CD  1 
ATOM 2935 N N   . GLN A 1 384 ? 88.403  28.662 58.388  1.00 0.49 ? 384 GLN A N   1 
ATOM 2936 C CA  . GLN A 1 384 ? 89.764  29.140 58.506  1.00 0.49 ? 384 GLN A CA  1 
ATOM 2937 C C   . GLN A 1 384 ? 89.935  30.344 59.427  1.00 0.49 ? 384 GLN A C   1 
ATOM 2938 O O   . GLN A 1 384 ? 88.982  31.049 59.761  1.00 0.49 ? 384 GLN A O   1 
ATOM 2939 C CB  . GLN A 1 384 ? 90.322  29.499 57.098  1.00 0.49 ? 384 GLN A CB  1 
ATOM 2940 C CG  . GLN A 1 384 ? 89.632  30.714 56.414  1.00 0.49 ? 384 GLN A CG  1 
ATOM 2941 C CD  . GLN A 1 384 ? 90.234  31.071 55.049  1.00 0.49 ? 384 GLN A CD  1 
ATOM 2942 O OE1 . GLN A 1 384 ? 90.738  32.177 54.822  1.00 0.49 ? 384 GLN A OE1 1 
ATOM 2943 N NE2 . GLN A 1 384 ? 90.156  30.111 54.102  1.00 0.49 ? 384 GLN A NE2 1 
ATOM 2944 N N   . ARG A 1 385 ? 91.190  30.636 59.836  1.00 0.53 ? 385 ARG A N   1 
ATOM 2945 C CA  . ARG A 1 385 ? 91.521  31.848 60.562  1.00 0.53 ? 385 ARG A CA  1 
ATOM 2946 C C   . ARG A 1 385 ? 92.622  32.581 59.816  1.00 0.53 ? 385 ARG A C   1 
ATOM 2947 O O   . ARG A 1 385 ? 93.422  31.979 59.104  1.00 0.53 ? 385 ARG A O   1 
ATOM 2948 C CB  . ARG A 1 385 ? 91.931  31.557 62.029  1.00 0.53 ? 385 ARG A CB  1 
ATOM 2949 C CG  . ARG A 1 385 ? 91.916  32.797 62.950  1.00 0.53 ? 385 ARG A CG  1 
ATOM 2950 C CD  . ARG A 1 385 ? 92.218  32.530 64.432  1.00 0.53 ? 385 ARG A CD  1 
ATOM 2951 N NE  . ARG A 1 385 ? 93.678  32.226 64.550  1.00 0.53 ? 385 ARG A NE  1 
ATOM 2952 C CZ  . ARG A 1 385 ? 94.261  31.868 65.705  1.00 0.53 ? 385 ARG A CZ  1 
ATOM 2953 N NH1 . ARG A 1 385 ? 95.544  31.518 65.671  1.00 0.53 ? 385 ARG A NH1 1 
ATOM 2954 N NH2 . ARG A 1 385 ? 93.616  31.857 66.860  1.00 0.53 ? 385 ARG A NH2 1 
ATOM 2955 N N   . GLN A 1 386 ? 92.662  33.924 59.936  1.00 0.61 ? 386 GLN A N   1 
ATOM 2956 C CA  . GLN A 1 386 ? 93.552  34.807 59.203  1.00 0.61 ? 386 GLN A CA  1 
ATOM 2957 C C   . GLN A 1 386 ? 95.030  34.724 59.566  1.00 0.61 ? 386 GLN A C   1 
ATOM 2958 O O   . GLN A 1 386 ? 95.891  35.069 58.761  1.00 0.61 ? 386 GLN A O   1 
ATOM 2959 C CB  . GLN A 1 386 ? 93.046  36.253 59.407  1.00 0.61 ? 386 GLN A CB  1 
ATOM 2960 C CG  . GLN A 1 386 ? 93.734  37.348 58.555  1.00 0.61 ? 386 GLN A CG  1 
ATOM 2961 C CD  . GLN A 1 386 ? 92.975  38.671 58.720  1.00 0.61 ? 386 GLN A CD  1 
ATOM 2962 O OE1 . GLN A 1 386 ? 91.927  38.691 59.369  1.00 0.61 ? 386 GLN A OE1 1 
ATOM 2963 N NE2 . GLN A 1 386 ? 93.502  39.757 58.117  1.00 0.61 ? 386 GLN A NE2 1 
ATOM 2964 N N   . LYS A 1 387 ? 95.373  34.259 60.782  1.00 0.56 ? 387 LYS A N   1 
ATOM 2965 C CA  . LYS A 1 387 ? 96.742  34.291 61.247  1.00 0.56 ? 387 LYS A CA  1 
ATOM 2966 C C   . LYS A 1 387 ? 97.034  33.134 62.183  1.00 0.56 ? 387 LYS A C   1 
ATOM 2967 O O   . LYS A 1 387 ? 96.140  32.569 62.820  1.00 0.56 ? 387 LYS A O   1 
ATOM 2968 C CB  . LYS A 1 387 ? 97.064  35.651 61.914  1.00 0.56 ? 387 LYS A CB  1 
ATOM 2969 C CG  . LYS A 1 387 ? 96.260  35.952 63.188  1.00 0.56 ? 387 LYS A CG  1 
ATOM 2970 C CD  . LYS A 1 387 ? 96.176  37.455 63.507  1.00 0.56 ? 387 LYS A CD  1 
ATOM 2971 C CE  . LYS A 1 387 ? 97.531  38.157 63.666  1.00 0.56 ? 387 LYS A CE  1 
ATOM 2972 N NZ  . LYS A 1 387 ? 97.313  39.539 64.141  1.00 0.56 ? 387 LYS A NZ  1 
ATOM 2973 N N   . LYS A 1 388 ? 98.317  32.715 62.231  1.00 0.48 ? 388 LYS A N   1 
ATOM 2974 C CA  . LYS A 1 388 ? 98.762  31.554 62.979  1.00 0.48 ? 388 LYS A CA  1 
ATOM 2975 C C   . LYS A 1 388 ? 98.860  31.762 64.485  1.00 0.48 ? 388 LYS A C   1 
ATOM 2976 O O   . LYS A 1 388 ? 98.369  30.932 65.241  1.00 0.48 ? 388 LYS A O   1 
ATOM 2977 C CB  . LYS A 1 388 ? 100.119 31.049 62.426  1.00 0.48 ? 388 LYS A CB  1 
ATOM 2978 C CG  . LYS A 1 388 ? 100.129 30.719 60.918  1.00 0.48 ? 388 LYS A CG  1 
ATOM 2979 C CD  . LYS A 1 388 ? 99.200  29.559 60.507  1.00 0.48 ? 388 LYS A CD  1 
ATOM 2980 C CE  . LYS A 1 388 ? 99.346  29.194 59.023  1.00 0.48 ? 388 LYS A CE  1 
ATOM 2981 N NZ  . LYS A 1 388 ? 98.447  28.075 58.655  1.00 0.48 ? 388 LYS A NZ  1 
ATOM 2982 N N   . GLN A 1 389 ? 99.451  32.877 64.961  1.00 0.50 ? 389 GLN A N   1 
ATOM 2983 C CA  . GLN A 1 389 ? 99.660  33.098 66.383  1.00 0.50 ? 389 GLN A CA  1 
ATOM 2984 C C   . GLN A 1 389 ? 99.679  34.592 66.670  1.00 0.50 ? 389 GLN A C   1 
ATOM 2985 O O   . GLN A 1 389 ? 100.075 35.379 65.812  1.00 0.50 ? 389 GLN A O   1 
ATOM 2986 C CB  . GLN A 1 389 ? 101.004 32.437 66.820  1.00 0.50 ? 389 GLN A CB  1 
ATOM 2987 C CG  . GLN A 1 389 ? 101.533 32.714 68.255  1.00 0.50 ? 389 GLN A CG  1 
ATOM 2988 C CD  . GLN A 1 389 ? 100.595 32.211 69.352  1.00 0.50 ? 389 GLN A CD  1 
ATOM 2989 O OE1 . GLN A 1 389 ? 99.444  31.849 69.125  1.00 0.50 ? 389 GLN A OE1 1 
ATOM 2990 N NE2 . GLN A 1 389 ? 101.094 32.218 70.609  1.00 0.50 ? 389 GLN A NE2 1 
ATOM 2991 N N   . GLN A 1 390 ? 99.239  35.030 67.877  1.00 0.57 ? 390 GLN A N   1 
ATOM 2992 C CA  . GLN A 1 390 ? 99.437  36.401 68.328  1.00 0.57 ? 390 GLN A CA  1 
ATOM 2993 C C   . GLN A 1 390 ? 99.381  36.501 69.851  1.00 0.57 ? 390 GLN A C   1 
ATOM 2994 O O   . GLN A 1 390 ? 98.654  35.755 70.500  1.00 0.57 ? 390 GLN A O   1 
ATOM 2995 C CB  . GLN A 1 390 ? 98.385  37.379 67.728  1.00 0.57 ? 390 GLN A CB  1 
ATOM 2996 C CG  . GLN A 1 390 ? 96.911  37.044 68.073  1.00 0.57 ? 390 GLN A CG  1 
ATOM 2997 C CD  . GLN A 1 390 ? 95.932  37.897 67.267  1.00 0.57 ? 390 GLN A CD  1 
ATOM 2998 O OE1 . GLN A 1 390 ? 96.300  38.861 66.589  1.00 0.57 ? 390 GLN A OE1 1 
ATOM 2999 N NE2 . GLN A 1 390 ? 94.633  37.517 67.318  1.00 0.57 ? 390 GLN A NE2 1 
ATOM 3000 N N   . THR A 1 391 ? 100.124 37.448 70.467  1.00 0.54 ? 391 THR A N   1 
ATOM 3001 C CA  . THR A 1 391 ? 99.990  37.768 71.892  1.00 0.54 ? 391 THR A CA  1 
ATOM 3002 C C   . THR A 1 391 ? 100.359 39.227 72.085  1.00 0.54 ? 391 THR A C   1 
ATOM 3003 O O   . THR A 1 391 ? 101.235 39.741 71.395  1.00 0.54 ? 391 THR A O   1 
ATOM 3004 C CB  . THR A 1 391 ? 100.787 36.871 72.858  1.00 0.54 ? 391 THR A CB  1 
ATOM 3005 O OG1 . THR A 1 391 ? 100.688 37.301 74.212  1.00 0.54 ? 391 THR A OG1 1 
ATOM 3006 C CG2 . THR A 1 391 ? 102.285 36.824 72.525  1.00 0.54 ? 391 THR A CG2 1 
ATOM 3007 N N   . VAL A 1 392 ? 99.666  39.939 73.003  1.00 0.52 ? 392 VAL A N   1 
ATOM 3008 C CA  . VAL A 1 392 ? 99.878  41.338 73.347  1.00 0.52 ? 392 VAL A CA  1 
ATOM 3009 C C   . VAL A 1 392 ? 99.524  41.386 74.818  1.00 0.52 ? 392 VAL A C   1 
ATOM 3010 O O   . VAL A 1 392 ? 98.638  40.642 75.229  1.00 0.52 ? 392 VAL A O   1 
ATOM 3011 C CB  . VAL A 1 392 ? 98.965  42.309 72.583  1.00 0.52 ? 392 VAL A CB  1 
ATOM 3012 C CG1 . VAL A 1 392 ? 99.048  43.760 73.114  1.00 0.52 ? 392 VAL A CG1 1 
ATOM 3013 C CG2 . VAL A 1 392 ? 99.337  42.297 71.090  1.00 0.52 ? 392 VAL A CG2 1 
ATOM 3014 N N   . THR A 1 393 ? 100.235 42.192 75.651  1.00 0.46 ? 393 THR A N   1 
ATOM 3015 C CA  . THR A 1 393 ? 99.989  42.388 77.095  1.00 0.46 ? 393 THR A CA  1 
ATOM 3016 C C   . THR A 1 393 ? 99.933  41.108 77.914  1.00 0.46 ? 393 THR A C   1 
ATOM 3017 O O   . THR A 1 393 ? 99.258  41.019 78.937  1.00 0.46 ? 393 THR A O   1 
ATOM 3018 C CB  . THR A 1 393 ? 98.832  43.329 77.477  1.00 0.46 ? 393 THR A CB  1 
ATOM 3019 O OG1 . THR A 1 393 ? 97.622  43.040 76.796  1.00 0.46 ? 393 THR A OG1 1 
ATOM 3020 C CG2 . THR A 1 393 ? 99.180  44.779 77.120  1.00 0.46 ? 393 THR A CG2 1 
ATOM 3021 N N   . LEU A 1 394 ? 100.702 40.091 77.464  1.00 0.41 ? 394 LEU A N   1 
ATOM 3022 C CA  . LEU A 1 394 ? 100.783 38.746 78.010  1.00 0.41 ? 394 LEU A CA  1 
ATOM 3023 C C   . LEU A 1 394 ? 99.465  37.970 77.957  1.00 0.41 ? 394 LEU A C   1 
ATOM 3024 O O   . LEU A 1 394 ? 99.255  36.998 78.680  1.00 0.41 ? 394 LEU A O   1 
ATOM 3025 C CB  . LEU A 1 394 ? 101.460 38.668 79.405  1.00 0.41 ? 394 LEU A CB  1 
ATOM 3026 C CG  . LEU A 1 394 ? 102.961 39.046 79.444  1.00 0.41 ? 394 LEU A CG  1 
ATOM 3027 C CD1 . LEU A 1 394 ? 103.231 40.562 79.463  1.00 0.41 ? 394 LEU A CD1 1 
ATOM 3028 C CD2 . LEU A 1 394 ? 103.630 38.404 80.671  1.00 0.41 ? 394 LEU A CD2 1 
ATOM 3029 N N   . LEU A 1 395 ? 98.550  38.348 77.040  1.00 0.53 ? 395 LEU A N   1 
ATOM 3030 C CA  . LEU A 1 395 ? 97.303  37.649 76.789  1.00 0.53 ? 395 LEU A CA  1 
ATOM 3031 C C   . LEU A 1 395 ? 97.539  36.225 76.270  1.00 0.53 ? 395 LEU A C   1 
ATOM 3032 O O   . LEU A 1 395 ? 98.309  36.069 75.321  1.00 0.53 ? 395 LEU A O   1 
ATOM 3033 C CB  . LEU A 1 395 ? 96.481  38.496 75.778  1.00 0.53 ? 395 LEU A CB  1 
ATOM 3034 C CG  . LEU A 1 395 ? 94.996  38.150 75.526  1.00 0.53 ? 395 LEU A CG  1 
ATOM 3035 C CD1 . LEU A 1 395 ? 94.294  39.352 74.868  1.00 0.53 ? 395 LEU A CD1 1 
ATOM 3036 C CD2 . LEU A 1 395 ? 94.753  36.911 74.645  1.00 0.53 ? 395 LEU A CD2 1 
ATOM 3037 N N   . PRO A 1 396 ? 96.929  35.153 76.778  1.00 0.57 ? 396 PRO A N   1 
ATOM 3038 C CA  . PRO A 1 396 ? 97.304  33.788 76.412  1.00 0.57 ? 396 PRO A CA  1 
ATOM 3039 C C   . PRO A 1 396 ? 96.636  33.342 75.115  1.00 0.57 ? 396 PRO A C   1 
ATOM 3040 O O   . PRO A 1 396 ? 95.856  32.397 75.124  1.00 0.57 ? 396 PRO A O   1 
ATOM 3041 C CB  . PRO A 1 396 ? 96.821  32.966 77.622  1.00 0.57 ? 396 PRO A CB  1 
ATOM 3042 C CG  . PRO A 1 396 ? 95.608  33.738 78.141  1.00 0.57 ? 396 PRO A CG  1 
ATOM 3043 C CD  . PRO A 1 396 ? 96.027  35.189 77.928  1.00 0.57 ? 396 PRO A CD  1 
ATOM 3044 N N   . ALA A 1 397 ? 96.905  34.053 73.997  1.00 0.64 ? 397 ALA A N   1 
ATOM 3045 C CA  . ALA A 1 397 ? 96.631  33.683 72.614  1.00 0.64 ? 397 ALA A CA  1 
ATOM 3046 C C   . ALA A 1 397 ? 95.219  33.205 72.262  1.00 0.64 ? 397 ALA A C   1 
ATOM 3047 O O   . ALA A 1 397 ? 95.012  32.528 71.260  1.00 0.64 ? 397 ALA A O   1 
ATOM 3048 C CB  . ALA A 1 397 ? 97.713  32.689 72.158  1.00 0.64 ? 397 ALA A CB  1 
ATOM 3049 N N   . ALA A 1 398 ? 94.216  33.602 73.076  1.00 0.70 ? 398 ALA A N   1 
ATOM 3050 C CA  . ALA A 1 398 ? 92.851  33.108 73.041  1.00 0.70 ? 398 ALA A CA  1 
ATOM 3051 C C   . ALA A 1 398 ? 92.719  31.585 73.262  1.00 0.70 ? 398 ALA A C   1 
ATOM 3052 O O   . ALA A 1 398 ? 91.721  30.972 72.901  1.00 0.70 ? 398 ALA A O   1 
ATOM 3053 C CB  . ALA A 1 398 ? 92.105  33.625 71.789  1.00 0.70 ? 398 ALA A CB  1 
ATOM 3054 N N   . ASP A 1 399 ? 93.695  30.921 73.931  1.00 0.63 ? 399 ASP A N   1 
ATOM 3055 C CA  . ASP A 1 399 ? 93.702  29.479 74.149  1.00 0.63 ? 399 ASP A CA  1 
ATOM 3056 C C   . ASP A 1 399 ? 92.538  28.975 75.010  1.00 0.63 ? 399 ASP A C   1 
ATOM 3057 O O   . ASP A 1 399 ? 91.908  27.952 74.725  1.00 0.63 ? 399 ASP A O   1 
ATOM 3058 C CB  . ASP A 1 399 ? 95.060  29.029 74.764  1.00 0.63 ? 399 ASP A CB  1 
ATOM 3059 C CG  . ASP A 1 399 ? 96.179  28.935 73.730  1.00 0.63 ? 399 ASP A CG  1 
ATOM 3060 O OD1 . ASP A 1 399 ? 95.894  28.512 72.575  1.00 0.63 ? 399 ASP A OD1 1 
ATOM 3061 O OD2 . ASP A 1 399 ? 97.357  29.195 74.085  1.00 0.63 ? 399 ASP A OD2 1 
ATOM 3062 N N   . LEU A 1 400 ? 92.182  29.731 76.071  1.00 0.65 ? 400 LEU A N   1 
ATOM 3063 C CA  . LEU A 1 400 ? 91.006  29.483 76.890  1.00 0.65 ? 400 LEU A CA  1 
ATOM 3064 C C   . LEU A 1 400 ? 89.719  29.580 76.074  1.00 0.65 ? 400 LEU A C   1 
ATOM 3065 O O   . LEU A 1 400 ? 88.842  28.721 76.180  1.00 0.65 ? 400 LEU A O   1 
ATOM 3066 C CB  . LEU A 1 400 ? 90.971  30.438 78.112  1.00 0.65 ? 400 LEU A CB  1 
ATOM 3067 C CG  . LEU A 1 400 ? 89.766  30.287 79.074  1.00 0.65 ? 400 LEU A CG  1 
ATOM 3068 C CD1 . LEU A 1 400 ? 89.621  28.877 79.667  1.00 0.65 ? 400 LEU A CD1 1 
ATOM 3069 C CD2 . LEU A 1 400 ? 89.852  31.320 80.209  1.00 0.65 ? 400 LEU A CD2 1 
ATOM 3070 N N   . ASP A 1 401 ? 89.617  30.591 75.180  1.00 0.71 ? 401 ASP A N   1 
ATOM 3071 C CA  . ASP A 1 401 ? 88.549  30.758 74.217  1.00 0.71 ? 401 ASP A CA  1 
ATOM 3072 C C   . ASP A 1 401 ? 88.467  29.592 73.240  1.00 0.71 ? 401 ASP A C   1 
ATOM 3073 O O   . ASP A 1 401 ? 87.394  29.030 73.028  1.00 0.71 ? 401 ASP A O   1 
ATOM 3074 C CB  . ASP A 1 401 ? 88.726  32.090 73.449  1.00 0.71 ? 401 ASP A CB  1 
ATOM 3075 C CG  . ASP A 1 401 ? 88.739  33.235 74.441  1.00 0.71 ? 401 ASP A CG  1 
ATOM 3076 O OD1 . ASP A 1 401 ? 87.617  33.549 74.911  1.00 0.71 ? 401 ASP A OD1 1 
ATOM 3077 O OD2 . ASP A 1 401 ? 89.832  33.785 74.742  1.00 0.71 ? 401 ASP A OD2 1 
ATOM 3078 N N   . ASP A 1 402 ? 89.606  29.127 72.681  1.00 0.68 ? 402 ASP A N   1 
ATOM 3079 C CA  . ASP A 1 402 ? 89.638  27.948 71.834  1.00 0.68 ? 402 ASP A CA  1 
ATOM 3080 C C   . ASP A 1 402 ? 89.098  26.707 72.519  1.00 0.68 ? 402 ASP A C   1 
ATOM 3081 O O   . ASP A 1 402 ? 88.234  26.022 71.980  1.00 0.68 ? 402 ASP A O   1 
ATOM 3082 C CB  . ASP A 1 402 ? 91.081  27.585 71.405  1.00 0.68 ? 402 ASP A CB  1 
ATOM 3083 C CG  . ASP A 1 402 ? 91.602  28.444 70.273  1.00 0.68 ? 402 ASP A CG  1 
ATOM 3084 O OD1 . ASP A 1 402 ? 90.784  29.061 69.551  1.00 0.68 ? 402 ASP A OD1 1 
ATOM 3085 O OD2 . ASP A 1 402 ? 92.835  28.341 70.046  1.00 0.68 ? 402 ASP A OD2 1 
ATOM 3086 N N   . PHE A 1 403 ? 89.555  26.418 73.754  1.00 0.67 ? 403 PHE A N   1 
ATOM 3087 C CA  . PHE A 1 403 ? 89.059  25.320 74.560  1.00 0.67 ? 403 PHE A CA  1 
ATOM 3088 C C   . PHE A 1 403 ? 87.565  25.452 74.870  1.00 0.67 ? 403 PHE A C   1 
ATOM 3089 O O   . PHE A 1 403 ? 86.782  24.537 74.614  1.00 0.67 ? 403 PHE A O   1 
ATOM 3090 C CB  . PHE A 1 403 ? 89.900  25.257 75.875  1.00 0.67 ? 403 PHE A CB  1 
ATOM 3091 C CG  . PHE A 1 403 ? 89.383  24.278 76.905  1.00 0.67 ? 403 PHE A CG  1 
ATOM 3092 C CD1 . PHE A 1 403 ? 89.577  22.899 76.753  1.00 0.67 ? 403 PHE A CD1 1 
ATOM 3093 C CD2 . PHE A 1 403 ? 88.659  24.741 78.016  1.00 0.67 ? 403 PHE A CD2 1 
ATOM 3094 C CE1 . PHE A 1 403 ? 89.053  21.997 77.687  1.00 0.67 ? 403 PHE A CE1 1 
ATOM 3095 C CE2 . PHE A 1 403 ? 88.129  23.843 78.952  1.00 0.67 ? 403 PHE A CE2 1 
ATOM 3096 C CZ  . PHE A 1 403 ? 88.328  22.467 78.789  1.00 0.67 ? 403 PHE A CZ  1 
ATOM 3097 N N   . SER A 1 404 ? 87.117  26.614 75.388  1.00 0.72 ? 404 SER A N   1 
ATOM 3098 C CA  . SER A 1 404 ? 85.731  26.819 75.790  1.00 0.72 ? 404 SER A CA  1 
ATOM 3099 C C   . SER A 1 404 ? 84.742  26.807 74.645  1.00 0.72 ? 404 SER A C   1 
ATOM 3100 O O   . SER A 1 404 ? 83.720  26.127 74.713  1.00 0.72 ? 404 SER A O   1 
ATOM 3101 C CB  . SER A 1 404 ? 85.534  28.106 76.629  1.00 0.72 ? 404 SER A CB  1 
ATOM 3102 O OG  . SER A 1 404 ? 85.816  29.295 75.895  1.00 0.72 ? 404 SER A OG  1 
ATOM 3103 N N   . LYS A 1 405 ? 85.042  27.508 73.533  1.00 0.72 ? 405 LYS A N   1 
ATOM 3104 C CA  . LYS A 1 405 ? 84.210  27.527 72.347  1.00 0.72 ? 405 LYS A CA  1 
ATOM 3105 C C   . LYS A 1 405 ? 84.160  26.189 71.628  1.00 0.72 ? 405 LYS A C   1 
ATOM 3106 O O   . LYS A 1 405 ? 83.109  25.790 71.131  1.00 0.72 ? 405 LYS A O   1 
ATOM 3107 C CB  . LYS A 1 405 ? 84.572  28.652 71.344  1.00 0.72 ? 405 LYS A CB  1 
ATOM 3108 C CG  . LYS A 1 405 ? 84.042  30.045 71.748  1.00 0.72 ? 405 LYS A CG  1 
ATOM 3109 C CD  . LYS A 1 405 ? 85.038  30.919 72.543  1.00 0.72 ? 405 LYS A CD  1 
ATOM 3110 C CE  . LYS A 1 405 ? 84.492  32.320 72.860  1.00 0.72 ? 405 LYS A CE  1 
ATOM 3111 N NZ  . LYS A 1 405 ? 85.513  33.308 73.278  1.00 0.72 ? 405 LYS A NZ  1 
ATOM 3112 N N   . GLN A 1 406 ? 85.286  25.445 71.549  1.00 0.67 ? 406 GLN A N   1 
ATOM 3113 C CA  . GLN A 1 406 ? 85.283  24.092 71.013  1.00 0.67 ? 406 GLN A CA  1 
ATOM 3114 C C   . GLN A 1 406 ? 84.456  23.131 71.857  1.00 0.67 ? 406 GLN A C   1 
ATOM 3115 O O   . GLN A 1 406 ? 83.643  22.384 71.321  1.00 0.67 ? 406 GLN A O   1 
ATOM 3116 C CB  . GLN A 1 406 ? 86.723  23.564 70.766  1.00 0.67 ? 406 GLN A CB  1 
ATOM 3117 C CG  . GLN A 1 406 ? 87.412  24.316 69.592  1.00 0.67 ? 406 GLN A CG  1 
ATOM 3118 C CD  . GLN A 1 406 ? 88.913  24.028 69.440  1.00 0.67 ? 406 GLN A CD  1 
ATOM 3119 O OE1 . GLN A 1 406 ? 89.436  22.955 69.730  1.00 0.67 ? 406 GLN A OE1 1 
ATOM 3120 N NE2 . GLN A 1 406 ? 89.664  25.018 68.897  1.00 0.67 ? 406 GLN A NE2 1 
ATOM 3121 N N   . LEU A 1 407 ? 84.565  23.171 73.201  1.00 0.71 ? 407 LEU A N   1 
ATOM 3122 C CA  . LEU A 1 407 ? 83.682  22.409 74.072  1.00 0.71 ? 407 LEU A CA  1 
ATOM 3123 C C   . LEU A 1 407 ? 82.219  22.799 73.952  1.00 0.71 ? 407 LEU A C   1 
ATOM 3124 O O   . LEU A 1 407 ? 81.344  21.937 73.911  1.00 0.71 ? 407 LEU A O   1 
ATOM 3125 C CB  . LEU A 1 407 ? 84.085  22.544 75.559  1.00 0.71 ? 407 LEU A CB  1 
ATOM 3126 C CG  . LEU A 1 407 ? 84.975  21.400 76.079  1.00 0.71 ? 407 LEU A CG  1 
ATOM 3127 C CD1 . LEU A 1 407 ? 86.341  21.337 75.380  1.00 0.71 ? 407 LEU A CD1 1 
ATOM 3128 C CD2 . LEU A 1 407 ? 85.156  21.537 77.598  1.00 0.71 ? 407 LEU A CD2 1 
ATOM 3129 N N   . GLN A 1 408 ? 81.925  24.115 73.893  1.00 0.70 ? 408 GLN A N   1 
ATOM 3130 C CA  . GLN A 1 408 ? 80.582  24.635 73.737  1.00 0.70 ? 408 GLN A CA  1 
ATOM 3131 C C   . GLN A 1 408 ? 79.912  24.205 72.446  1.00 0.70 ? 408 GLN A C   1 
ATOM 3132 O O   . GLN A 1 408 ? 78.765  23.768 72.478  1.00 0.70 ? 408 GLN A O   1 
ATOM 3133 C CB  . GLN A 1 408 ? 80.573  26.178 73.823  1.00 0.70 ? 408 GLN A CB  1 
ATOM 3134 C CG  . GLN A 1 408 ? 79.169  26.818 73.726  1.00 0.70 ? 408 GLN A CG  1 
ATOM 3135 C CD  . GLN A 1 408 ? 79.245  28.328 73.955  1.00 0.70 ? 408 GLN A CD  1 
ATOM 3136 O OE1 . GLN A 1 408 ? 80.312  28.917 74.121  1.00 0.70 ? 408 GLN A OE1 1 
ATOM 3137 N NE2 . GLN A 1 408 ? 78.060  28.981 73.976  1.00 0.70 ? 408 GLN A NE2 1 
ATOM 3138 N N   . GLN A 1 409 ? 80.626  24.274 71.300  1.00 0.68 ? 409 GLN A N   1 
ATOM 3139 C CA  . GLN A 1 409 ? 80.161  23.749 70.023  1.00 0.68 ? 409 GLN A CA  1 
ATOM 3140 C C   . GLN A 1 409 ? 79.966  22.235 70.063  1.00 0.68 ? 409 GLN A C   1 
ATOM 3141 O O   . GLN A 1 409 ? 78.951  21.713 69.617  1.00 0.68 ? 409 GLN A O   1 
ATOM 3142 C CB  . GLN A 1 409 ? 81.108  24.184 68.868  1.00 0.68 ? 409 GLN A CB  1 
ATOM 3143 C CG  . GLN A 1 409 ? 80.541  23.993 67.433  1.00 0.68 ? 409 GLN A CG  1 
ATOM 3144 C CD  . GLN A 1 409 ? 80.690  22.570 66.879  1.00 0.68 ? 409 GLN A CD  1 
ATOM 3145 O OE1 . GLN A 1 409 ? 81.749  21.949 67.007  1.00 0.68 ? 409 GLN A OE1 1 
ATOM 3146 N NE2 . GLN A 1 409 ? 79.656  22.060 66.183  1.00 0.68 ? 409 GLN A NE2 1 
ATOM 3147 N N   . SER A 1 410 ? 80.906  21.473 70.663  1.00 0.66 ? 410 SER A N   1 
ATOM 3148 C CA  . SER A 1 410 ? 80.779  20.022 70.789  1.00 0.66 ? 410 SER A CA  1 
ATOM 3149 C C   . SER A 1 410 ? 79.599  19.537 71.609  1.00 0.66 ? 410 SER A C   1 
ATOM 3150 O O   . SER A 1 410 ? 78.941  18.565 71.251  1.00 0.66 ? 410 SER A O   1 
ATOM 3151 C CB  . SER A 1 410 ? 82.006  19.359 71.458  1.00 0.66 ? 410 SER A CB  1 
ATOM 3152 O OG  . SER A 1 410 ? 83.173  19.476 70.650  1.00 0.66 ? 410 SER A OG  1 
ATOM 3153 N N   . MET A 1 411 ? 79.308  20.167 72.767  1.00 0.61 ? 411 MET A N   1 
ATOM 3154 C CA  . MET A 1 411 ? 78.128  19.831 73.545  1.00 0.61 ? 411 MET A CA  1 
ATOM 3155 C C   . MET A 1 411 ? 76.830  20.269 72.883  1.00 0.61 ? 411 MET A C   1 
ATOM 3156 O O   . MET A 1 411 ? 75.875  19.502 72.813  1.00 0.61 ? 411 MET A O   1 
ATOM 3157 C CB  . MET A 1 411 ? 78.217  20.320 75.017  1.00 0.61 ? 411 MET A CB  1 
ATOM 3158 C CG  . MET A 1 411 ? 78.146  21.845 75.221  1.00 0.61 ? 411 MET A CG  1 
ATOM 3159 S SD  . MET A 1 411 ? 78.371  22.411 76.937  1.00 0.61 ? 411 MET A SD  1 
ATOM 3160 C CE  . MET A 1 411 ? 80.153  22.101 77.064  1.00 0.61 ? 411 MET A CE  1 
ATOM 3161 N N   . SER A 1 412 ? 76.762  21.490 72.305  1.00 0.63 ? 412 SER A N   1 
ATOM 3162 C CA  . SER A 1 412 ? 75.571  21.963 71.615  1.00 0.63 ? 412 SER A CA  1 
ATOM 3163 C C   . SER A 1 412 ? 75.244  21.148 70.374  1.00 0.63 ? 412 SER A C   1 
ATOM 3164 O O   . SER A 1 412 ? 74.073  20.913 70.102  1.00 0.63 ? 412 SER A O   1 
ATOM 3165 C CB  . SER A 1 412 ? 75.596  23.481 71.284  1.00 0.63 ? 412 SER A CB  1 
ATOM 3166 O OG  . SER A 1 412 ? 76.702  23.807 70.448  1.00 0.63 ? 412 SER A OG  1 
ATOM 3167 N N   . SER A 1 413 ? 76.249  20.628 69.633  1.00 0.58 ? 413 SER A N   1 
ATOM 3168 C CA  . SER A 1 413 ? 76.024  19.751 68.488  1.00 0.58 ? 413 SER A CA  1 
ATOM 3169 C C   . SER A 1 413 ? 75.796  18.293 68.864  1.00 0.58 ? 413 SER A C   1 
ATOM 3170 O O   . SER A 1 413 ? 75.515  17.449 68.015  1.00 0.58 ? 413 SER A O   1 
ATOM 3171 C CB  . SER A 1 413 ? 77.170  19.813 67.440  1.00 0.58 ? 413 SER A CB  1 
ATOM 3172 O OG  . SER A 1 413 ? 78.407  19.255 67.897  1.00 0.58 ? 413 SER A OG  1 
ATOM 3173 N N   . ALA A 1 414 ? 75.880  17.953 70.167  1.00 0.51 ? 414 ALA A N   1 
ATOM 3174 C CA  . ALA A 1 414 ? 75.350  16.719 70.705  1.00 0.51 ? 414 ALA A CA  1 
ATOM 3175 C C   . ALA A 1 414 ? 73.896  16.885 71.149  1.00 0.51 ? 414 ALA A C   1 
ATOM 3176 O O   . ALA A 1 414 ? 73.059  16.019 70.903  1.00 0.51 ? 414 ALA A O   1 
ATOM 3177 C CB  . ALA A 1 414 ? 76.227  16.238 71.876  1.00 0.51 ? 414 ALA A CB  1 
ATOM 3178 N N   . ASP A 1 415 ? 73.563  18.034 71.781  1.00 0.45 ? 415 ASP A N   1 
ATOM 3179 C CA  . ASP A 1 415 ? 72.229  18.369 72.246  1.00 0.45 ? 415 ASP A CA  1 
ATOM 3180 C C   . ASP A 1 415 ? 71.283  18.799 71.111  1.00 0.45 ? 415 ASP A C   1 
ATOM 3181 O O   . ASP A 1 415 ? 70.059  18.796 71.247  1.00 0.45 ? 415 ASP A O   1 
ATOM 3182 C CB  . ASP A 1 415 ? 72.315  19.537 73.267  1.00 0.45 ? 415 ASP A CB  1 
ATOM 3183 C CG  . ASP A 1 415 ? 73.026  19.161 74.562  1.00 0.45 ? 415 ASP A CG  1 
ATOM 3184 O OD1 . ASP A 1 415 ? 73.177  17.950 74.856  1.00 0.45 ? 415 ASP A OD1 1 
ATOM 3185 O OD2 . ASP A 1 415 ? 73.387  20.121 75.295  1.00 0.45 ? 415 ASP A OD2 1 
ATOM 3186 N N   . SER A 1 416 ? 71.824  19.186 69.938  1.00 0.47 ? 416 SER A N   1 
ATOM 3187 C CA  . SER A 1 416 ? 71.049  19.615 68.786  1.00 0.47 ? 416 SER A CA  1 
ATOM 3188 C C   . SER A 1 416 ? 71.731  19.187 67.506  1.00 0.47 ? 416 SER A C   1 
ATOM 3189 O O   . SER A 1 416 ? 72.875  18.758 67.503  1.00 0.47 ? 416 SER A O   1 
ATOM 3190 C CB  . SER A 1 416 ? 70.718  21.142 68.758  1.00 0.47 ? 416 SER A CB  1 
ATOM 3191 O OG  . SER A 1 416 ? 71.779  21.984 68.299  1.00 0.47 ? 416 SER A OG  1 
ATOM 3192 N N   . THR A 1 417 ? 71.023  19.232 66.363  1.00 0.44 ? 417 THR A N   1 
ATOM 3193 C CA  . THR A 1 417 ? 71.523  18.688 65.103  1.00 0.44 ? 417 THR A CA  1 
ATOM 3194 C C   . THR A 1 417 ? 72.716  19.363 64.434  1.00 0.44 ? 417 THR A C   1 
ATOM 3195 O O   . THR A 1 417 ? 73.585  18.664 63.920  1.00 0.44 ? 417 THR A O   1 
ATOM 3196 C CB  . THR A 1 417 ? 70.438  18.645 64.036  1.00 0.44 ? 417 THR A CB  1 
ATOM 3197 O OG1 . THR A 1 417 ? 69.781  19.902 63.923  1.00 0.44 ? 417 THR A OG1 1 
ATOM 3198 C CG2 . THR A 1 417 ? 69.362  17.629 64.427  1.00 0.44 ? 417 THR A CG2 1 
ATOM 3199 N N   . GLN A 1 418 ? 72.750  20.711 64.345  1.00 0.57 ? 418 GLN A N   1 
ATOM 3200 C CA  . GLN A 1 418 ? 73.704  21.406 63.485  1.00 0.57 ? 418 GLN A CA  1 
ATOM 3201 C C   . GLN A 1 418 ? 74.450  22.577 64.122  1.00 0.57 ? 418 GLN A C   1 
ATOM 3202 O O   . GLN A 1 418 ? 75.117  23.320 63.408  1.00 0.57 ? 418 GLN A O   1 
ATOM 3203 C CB  . GLN A 1 418 ? 72.962  22.029 62.269  1.00 0.57 ? 418 GLN A CB  1 
ATOM 3204 C CG  . GLN A 1 418 ? 72.281  21.042 61.300  1.00 0.57 ? 418 GLN A CG  1 
ATOM 3205 C CD  . GLN A 1 418 ? 73.293  20.166 60.565  1.00 0.57 ? 418 GLN A CD  1 
ATOM 3206 O OE1 . GLN A 1 418 ? 74.497  20.401 60.500  1.00 0.57 ? 418 GLN A OE1 1 
ATOM 3207 N NE2 . GLN A 1 418 ? 72.764  19.097 59.926  1.00 0.57 ? 418 GLN A NE2 1 
ATOM 3208 N N   . ALA A 1 419 ? 74.338  22.794 65.439  1.00 0.70 ? 419 ALA A N   1 
ATOM 3209 C CA  . ALA A 1 419 ? 75.015  23.875 66.136  1.00 0.70 ? 419 ALA A CA  1 
ATOM 3210 C C   . ALA A 1 419 ? 76.572  23.769 66.237  1.00 0.70 ? 419 ALA A C   1 
ATOM 3211 O O   . ALA A 1 419 ? 77.138  22.756 65.740  1.00 0.70 ? 419 ALA A O   1 
ATOM 3212 C CB  . ALA A 1 419 ? 74.477  23.909 67.573  1.00 0.70 ? 419 ALA A CB  1 
ATOM 3213 O OXT . ALA A 1 419 ? 77.195  24.693 66.837  1.00 0.70 ? 419 ALA A OXT 1 
ATOM 3214 N N   . MET B 1 1   ? 16.730  87.266 47.654  1.00 0.55 ? 1   MET B N   1 
ATOM 3215 C CA  . MET B 1 1   ? 17.809  87.005 46.634  1.00 0.55 ? 1   MET B CA  1 
ATOM 3216 C C   . MET B 1 1   ? 17.823  85.560 46.188  1.00 0.55 ? 1   MET B C   1 
ATOM 3217 O O   . MET B 1 1   ? 17.293  84.713 46.898  1.00 0.55 ? 1   MET B O   1 
ATOM 3218 C CB  . MET B 1 1   ? 19.195  87.338 47.249  1.00 0.55 ? 1   MET B CB  1 
ATOM 3219 C CG  . MET B 1 1   ? 19.481  88.837 47.444  1.00 0.55 ? 1   MET B CG  1 
ATOM 3220 S SD  . MET B 1 1   ? 21.063  89.166 48.292  1.00 0.55 ? 1   MET B SD  1 
ATOM 3221 C CE  . MET B 1 1   ? 22.216  88.631 46.990  1.00 0.55 ? 1   MET B CE  1 
ATOM 3222 N N   . SER B 1 2   ? 18.429  85.247 45.030  1.00 0.67 ? 2   SER B N   1 
ATOM 3223 C CA  . SER B 1 2   ? 18.593  83.887 44.568  1.00 0.67 ? 2   SER B CA  1 
ATOM 3224 C C   . SER B 1 2   ? 19.875  83.882 43.755  1.00 0.67 ? 2   SER B C   1 
ATOM 3225 O O   . SER B 1 2   ? 20.288  84.932 43.267  1.00 0.67 ? 2   SER B O   1 
ATOM 3226 C CB  . SER B 1 2   ? 17.370  83.381 43.740  1.00 0.67 ? 2   SER B CB  1 
ATOM 3227 O OG  . SER B 1 2   ? 16.977  84.310 42.727  1.00 0.67 ? 2   SER B OG  1 
ATOM 3228 N N   . ASP B 1 3   ? 20.563  82.716 43.643  1.00 0.65 ? 3   ASP B N   1 
ATOM 3229 C CA  . ASP B 1 3   ? 21.824  82.545 42.926  1.00 0.65 ? 3   ASP B CA  1 
ATOM 3230 C C   . ASP B 1 3   ? 21.584  82.459 41.412  1.00 0.65 ? 3   ASP B C   1 
ATOM 3231 O O   . ASP B 1 3   ? 22.498  82.551 40.602  1.00 0.65 ? 3   ASP B O   1 
ATOM 3232 C CB  . ASP B 1 3   ? 22.541  81.265 43.476  1.00 0.65 ? 3   ASP B CB  1 
ATOM 3233 C CG  . ASP B 1 3   ? 24.053  81.226 43.284  1.00 0.65 ? 3   ASP B CG  1 
ATOM 3234 O OD1 . ASP B 1 3   ? 24.727  82.276 43.429  1.00 0.65 ? 3   ASP B OD1 1 
ATOM 3235 O OD2 . ASP B 1 3   ? 24.597  80.103 43.106  1.00 0.65 ? 3   ASP B OD2 1 
ATOM 3236 N N   . ASN B 1 4   ? 20.322  82.288 40.960  1.00 0.65 ? 4   ASN B N   1 
ATOM 3237 C CA  . ASN B 1 4   ? 20.023  82.295 39.543  1.00 0.65 ? 4   ASN B CA  1 
ATOM 3238 C C   . ASN B 1 4   ? 18.577  82.734 39.317  1.00 0.65 ? 4   ASN B C   1 
ATOM 3239 O O   . ASN B 1 4   ? 17.761  82.712 40.241  1.00 0.65 ? 4   ASN B O   1 
ATOM 3240 C CB  . ASN B 1 4   ? 20.362  80.931 38.869  1.00 0.65 ? 4   ASN B CB  1 
ATOM 3241 C CG  . ASN B 1 4   ? 19.429  79.837 39.371  1.00 0.65 ? 4   ASN B CG  1 
ATOM 3242 O OD1 . ASN B 1 4   ? 18.320  79.692 38.862  1.00 0.65 ? 4   ASN B OD1 1 
ATOM 3243 N ND2 . ASN B 1 4   ? 19.827  79.080 40.414  1.00 0.65 ? 4   ASN B ND2 1 
ATOM 3244 N N   . GLY B 1 5   ? 18.240  83.175 38.083  1.00 0.68 ? 5   GLY B N   1 
ATOM 3245 C CA  . GLY B 1 5   ? 16.917  83.694 37.783  1.00 0.68 ? 5   GLY B CA  1 
ATOM 3246 C C   . GLY B 1 5   ? 16.916  84.386 36.439  1.00 0.68 ? 5   GLY B C   1 
ATOM 3247 O O   . GLY B 1 5   ? 17.840  84.162 35.652  1.00 0.68 ? 5   GLY B O   1 
ATOM 3248 N N   . PRO B 1 6   ? 15.901  85.185 36.102  1.00 0.64 ? 6   PRO B N   1 
ATOM 3249 C CA  . PRO B 1 6   ? 15.920  86.134 34.986  1.00 0.64 ? 6   PRO B CA  1 
ATOM 3250 C C   . PRO B 1 6   ? 17.055  87.155 34.983  1.00 0.64 ? 6   PRO B C   1 
ATOM 3251 O O   . PRO B 1 6   ? 17.738  87.321 35.988  1.00 0.64 ? 6   PRO B O   1 
ATOM 3252 C CB  . PRO B 1 6   ? 14.551  86.838 35.059  1.00 0.64 ? 6   PRO B CB  1 
ATOM 3253 C CG  . PRO B 1 6   ? 13.666  85.897 35.877  1.00 0.64 ? 6   PRO B CG  1 
ATOM 3254 C CD  . PRO B 1 6   ? 14.655  85.283 36.864  1.00 0.64 ? 6   PRO B CD  1 
ATOM 3255 N N   . GLN B 1 7   ? 17.274  87.828 33.827  1.00 0.62 ? 7   GLN B N   1 
ATOM 3256 C CA  . GLN B 1 7   ? 18.217  88.933 33.640  1.00 0.62 ? 7   GLN B CA  1 
ATOM 3257 C C   . GLN B 1 7   ? 19.692  88.565 33.796  1.00 0.62 ? 7   GLN B C   1 
ATOM 3258 O O   . GLN B 1 7   ? 20.568  89.415 33.949  1.00 0.62 ? 7   GLN B O   1 
ATOM 3259 C CB  . GLN B 1 7   ? 17.877  90.183 34.495  1.00 0.62 ? 7   GLN B CB  1 
ATOM 3260 C CG  . GLN B 1 7   ? 16.423  90.702 34.403  1.00 0.62 ? 7   GLN B CG  1 
ATOM 3261 C CD  . GLN B 1 7   ? 16.038  91.355 33.079  1.00 0.62 ? 7   GLN B CD  1 
ATOM 3262 O OE1 . GLN B 1 7   ? 16.675  91.250 32.027  1.00 0.62 ? 7   GLN B OE1 1 
ATOM 3263 N NE2 . GLN B 1 7   ? 14.884  92.064 33.132  1.00 0.62 ? 7   GLN B NE2 1 
ATOM 3264 N N   . ASN B 1 8   ? 20.028  87.265 33.718  1.00 0.65 ? 8   ASN B N   1 
ATOM 3265 C CA  . ASN B 1 8   ? 21.390  86.788 33.814  1.00 0.65 ? 8   ASN B CA  1 
ATOM 3266 C C   . ASN B 1 8   ? 22.301  87.224 32.662  1.00 0.65 ? 8   ASN B C   1 
ATOM 3267 O O   . ASN B 1 8   ? 21.948  87.237 31.483  1.00 0.65 ? 8   ASN B O   1 
ATOM 3268 C CB  . ASN B 1 8   ? 21.448  85.269 34.128  1.00 0.65 ? 8   ASN B CB  1 
ATOM 3269 C CG  . ASN B 1 8   ? 20.870  84.450 32.989  1.00 0.65 ? 8   ASN B CG  1 
ATOM 3270 O OD1 . ASN B 1 8   ? 19.813  84.760 32.449  1.00 0.65 ? 8   ASN B OD1 1 
ATOM 3271 N ND2 . ASN B 1 8   ? 21.558  83.354 32.599  1.00 0.65 ? 8   ASN B ND2 1 
ATOM 3272 N N   . GLN B 1 9   ? 23.536  87.617 33.003  1.00 0.64 ? 9   GLN B N   1 
ATOM 3273 C CA  . GLN B 1 9   ? 24.399  88.398 32.137  1.00 0.64 ? 9   GLN B CA  1 
ATOM 3274 C C   . GLN B 1 9   ? 24.916  87.729 30.861  1.00 0.64 ? 9   GLN B C   1 
ATOM 3275 O O   . GLN B 1 9   ? 25.073  88.385 29.825  1.00 0.64 ? 9   GLN B O   1 
ATOM 3276 C CB  . GLN B 1 9   ? 25.573  88.947 32.987  1.00 0.64 ? 9   GLN B CB  1 
ATOM 3277 C CG  . GLN B 1 9   ? 26.516  89.950 32.277  1.00 0.64 ? 9   GLN B CG  1 
ATOM 3278 C CD  . GLN B 1 9   ? 27.761  90.264 33.115  1.00 0.64 ? 9   GLN B CD  1 
ATOM 3279 O OE1 . GLN B 1 9   ? 28.473  89.373 33.596  1.00 0.64 ? 9   GLN B OE1 1 
ATOM 3280 N NE2 . GLN B 1 9   ? 28.097  91.567 33.239  1.00 0.64 ? 9   GLN B NE2 1 
ATOM 3281 N N   . ARG B 1 10  ? 25.249  86.421 30.913  1.00 0.60 ? 10  ARG B N   1 
ATOM 3282 C CA  . ARG B 1 10  ? 26.081  85.776 29.906  1.00 0.60 ? 10  ARG B CA  1 
ATOM 3283 C C   . ARG B 1 10  ? 25.402  84.648 29.130  1.00 0.60 ? 10  ARG B C   1 
ATOM 3284 O O   . ARG B 1 10  ? 26.032  83.998 28.304  1.00 0.60 ? 10  ARG B O   1 
ATOM 3285 C CB  . ARG B 1 10  ? 27.397  85.290 30.569  1.00 0.60 ? 10  ARG B CB  1 
ATOM 3286 C CG  . ARG B 1 10  ? 28.160  86.447 31.258  1.00 0.60 ? 10  ARG B CG  1 
ATOM 3287 C CD  . ARG B 1 10  ? 29.546  86.084 31.801  1.00 0.60 ? 10  ARG B CD  1 
ATOM 3288 N NE  . ARG B 1 10  ? 29.953  87.253 32.638  1.00 0.60 ? 10  ARG B NE  1 
ATOM 3289 C CZ  . ARG B 1 10  ? 31.198  87.626 32.951  1.00 0.60 ? 10  ARG B CZ  1 
ATOM 3290 N NH1 . ARG B 1 10  ? 31.329  88.695 33.734  1.00 0.60 ? 10  ARG B NH1 1 
ATOM 3291 N NH2 . ARG B 1 10  ? 32.278  87.007 32.497  1.00 0.60 ? 10  ARG B NH2 1 
ATOM 3292 N N   . ASN B 1 11  ? 24.086  84.416 29.325  1.00 0.60 ? 11  ASN B N   1 
ATOM 3293 C CA  . ASN B 1 11  ? 23.304  83.580 28.425  1.00 0.60 ? 11  ASN B CA  1 
ATOM 3294 C C   . ASN B 1 11  ? 22.788  84.407 27.237  1.00 0.60 ? 11  ASN B C   1 
ATOM 3295 O O   . ASN B 1 11  ? 22.573  83.899 26.137  1.00 0.60 ? 11  ASN B O   1 
ATOM 3296 C CB  . ASN B 1 11  ? 22.156  82.926 29.234  1.00 0.60 ? 11  ASN B CB  1 
ATOM 3297 C CG  . ASN B 1 11  ? 21.315  82.005 28.361  1.00 0.60 ? 11  ASN B CG  1 
ATOM 3298 O OD1 . ASN B 1 11  ? 20.225  82.382 27.930  1.00 0.60 ? 11  ASN B OD1 1 
ATOM 3299 N ND2 . ASN B 1 11  ? 21.823  80.790 28.077  1.00 0.60 ? 11  ASN B ND2 1 
ATOM 3300 N N   . ALA B 1 12  ? 22.625  85.730 27.441  1.00 0.63 ? 12  ALA B N   1 
ATOM 3301 C CA  . ALA B 1 12  ? 22.410  86.721 26.409  1.00 0.63 ? 12  ALA B CA  1 
ATOM 3302 C C   . ALA B 1 12  ? 23.568  86.795 25.404  1.00 0.63 ? 12  ALA B C   1 
ATOM 3303 O O   . ALA B 1 12  ? 24.680  86.392 25.751  1.00 0.63 ? 12  ALA B O   1 
ATOM 3304 C CB  . ALA B 1 12  ? 22.188  88.093 27.083  1.00 0.63 ? 12  ALA B CB  1 
ATOM 3305 N N   . PRO B 1 13  ? 23.411  87.274 24.165  1.00 0.55 ? 13  PRO B N   1 
ATOM 3306 C CA  . PRO B 1 13  ? 24.497  87.306 23.188  1.00 0.55 ? 13  PRO B CA  1 
ATOM 3307 C C   . PRO B 1 13  ? 25.546  88.363 23.515  1.00 0.55 ? 13  PRO B C   1 
ATOM 3308 O O   . PRO B 1 13  ? 25.589  89.422 22.898  1.00 0.55 ? 13  PRO B O   1 
ATOM 3309 C CB  . PRO B 1 13  ? 23.779  87.589 21.854  1.00 0.55 ? 13  PRO B CB  1 
ATOM 3310 C CG  . PRO B 1 13  ? 22.518  88.356 22.259  1.00 0.55 ? 13  PRO B CG  1 
ATOM 3311 C CD  . PRO B 1 13  ? 22.141  87.719 23.595  1.00 0.55 ? 13  PRO B CD  1 
ATOM 3312 N N   . ARG B 1 14  ? 26.438  88.052 24.469  1.00 0.52 ? 14  ARG B N   1 
ATOM 3313 C CA  . ARG B 1 14  ? 27.471  88.924 24.989  1.00 0.52 ? 14  ARG B CA  1 
ATOM 3314 C C   . ARG B 1 14  ? 28.726  88.938 24.122  1.00 0.52 ? 14  ARG B C   1 
ATOM 3315 O O   . ARG B 1 14  ? 29.632  89.745 24.315  1.00 0.52 ? 14  ARG B O   1 
ATOM 3316 C CB  . ARG B 1 14  ? 27.817  88.403 26.415  1.00 0.52 ? 14  ARG B CB  1 
ATOM 3317 C CG  . ARG B 1 14  ? 28.605  89.358 27.340  1.00 0.52 ? 14  ARG B CG  1 
ATOM 3318 C CD  . ARG B 1 14  ? 27.950  90.716 27.630  1.00 0.52 ? 14  ARG B CD  1 
ATOM 3319 N NE  . ARG B 1 14  ? 26.620  90.461 28.287  1.00 0.52 ? 14  ARG B NE  1 
ATOM 3320 C CZ  . ARG B 1 14  ? 25.641  91.370 28.397  1.00 0.52 ? 14  ARG B CZ  1 
ATOM 3321 N NH1 . ARG B 1 14  ? 24.475  90.992 28.913  1.00 0.52 ? 14  ARG B NH1 1 
ATOM 3322 N NH2 . ARG B 1 14  ? 25.817  92.627 28.008  1.00 0.52 ? 14  ARG B NH2 1 
ATOM 3323 N N   . ILE B 1 15  ? 28.798  88.017 23.141  1.00 0.50 ? 15  ILE B N   1 
ATOM 3324 C CA  . ILE B 1 15  ? 29.972  87.766 22.323  1.00 0.50 ? 15  ILE B CA  1 
ATOM 3325 C C   . ILE B 1 15  ? 29.876  88.364 20.915  1.00 0.50 ? 15  ILE B C   1 
ATOM 3326 O O   . ILE B 1 15  ? 30.807  88.285 20.111  1.00 0.50 ? 15  ILE B O   1 
ATOM 3327 C CB  . ILE B 1 15  ? 30.195  86.250 22.278  1.00 0.50 ? 15  ILE B CB  1 
ATOM 3328 C CG1 . ILE B 1 15  ? 31.623  85.858 21.832  1.00 0.50 ? 15  ILE B CG1 1 
ATOM 3329 C CG2 . ILE B 1 15  ? 29.094  85.537 21.453  1.00 0.50 ? 15  ILE B CG2 1 
ATOM 3330 C CD1 . ILE B 1 15  ? 32.003  84.441 22.281  1.00 0.50 ? 15  ILE B CD1 1 
ATOM 3331 N N   . THR B 1 16  ? 28.737  88.998 20.558  1.00 0.45 ? 16  THR B N   1 
ATOM 3332 C CA  . THR B 1 16  ? 28.560  89.651 19.260  1.00 0.45 ? 16  THR B CA  1 
ATOM 3333 C C   . THR B 1 16  ? 29.205  91.021 19.175  1.00 0.45 ? 16  THR B C   1 
ATOM 3334 O O   . THR B 1 16  ? 29.873  91.328 18.191  1.00 0.45 ? 16  THR B O   1 
ATOM 3335 C CB  . THR B 1 16  ? 27.100  89.796 18.846  1.00 0.45 ? 16  THR B CB  1 
ATOM 3336 O OG1 . THR B 1 16  ? 26.352  90.457 19.854  1.00 0.45 ? 16  THR B OG1 1 
ATOM 3337 C CG2 . THR B 1 16  ? 26.471  88.408 18.649  1.00 0.45 ? 16  THR B CG2 1 
ATOM 3338 N N   . PHE B 1 17  ? 29.034  91.877 20.197  1.00 0.36 ? 17  PHE B N   1 
ATOM 3339 C CA  . PHE B 1 17  ? 29.597  93.210 20.240  1.00 0.36 ? 17  PHE B CA  1 
ATOM 3340 C C   . PHE B 1 17  ? 29.729  93.591 21.709  1.00 0.36 ? 17  PHE B C   1 
ATOM 3341 O O   . PHE B 1 17  ? 29.028  93.054 22.564  1.00 0.36 ? 17  PHE B O   1 
ATOM 3342 C CB  . PHE B 1 17  ? 28.702  94.206 19.436  1.00 0.36 ? 17  PHE B CB  1 
ATOM 3343 C CG  . PHE B 1 17  ? 29.201  95.630 19.406  1.00 0.36 ? 17  PHE B CG  1 
ATOM 3344 C CD1 . PHE B 1 17  ? 30.487  95.944 18.935  1.00 0.36 ? 17  PHE B CD1 1 
ATOM 3345 C CD2 . PHE B 1 17  ? 28.379  96.675 19.864  1.00 0.36 ? 17  PHE B CD2 1 
ATOM 3346 C CE1 . PHE B 1 17  ? 30.941  97.270 18.924  1.00 0.36 ? 17  PHE B CE1 1 
ATOM 3347 C CE2 . PHE B 1 17  ? 28.825  98.001 19.843  1.00 0.36 ? 17  PHE B CE2 1 
ATOM 3348 C CZ  . PHE B 1 17  ? 30.106  98.300 19.369  1.00 0.36 ? 17  PHE B CZ  1 
ATOM 3349 N N   . GLY B 1 18  ? 30.663  94.513 22.044  1.00 0.45 ? 18  GLY B N   1 
ATOM 3350 C CA  . GLY B 1 18  ? 31.149  94.708 23.412  1.00 0.45 ? 18  GLY B CA  1 
ATOM 3351 C C   . GLY B 1 18  ? 31.889  93.500 23.932  1.00 0.45 ? 18  GLY B C   1 
ATOM 3352 O O   . GLY B 1 18  ? 32.608  92.846 23.184  1.00 0.45 ? 18  GLY B O   1 
ATOM 3353 N N   . GLY B 1 19  ? 31.754  93.168 25.232  1.00 0.53 ? 19  GLY B N   1 
ATOM 3354 C CA  . GLY B 1 19  ? 32.310  91.911 25.703  1.00 0.53 ? 19  GLY B CA  1 
ATOM 3355 C C   . GLY B 1 19  ? 32.015  91.654 27.160  1.00 0.53 ? 19  GLY B C   1 
ATOM 3356 O O   . GLY B 1 19  ? 31.478  92.524 27.851  1.00 0.53 ? 19  GLY B O   1 
ATOM 3357 N N   . PRO B 1 20  ? 32.309  90.457 27.662  1.00 0.58 ? 20  PRO B N   1 
ATOM 3358 C CA  . PRO B 1 20  ? 32.360  90.163 29.090  1.00 0.58 ? 20  PRO B CA  1 
ATOM 3359 C C   . PRO B 1 20  ? 33.620  90.710 29.749  1.00 0.58 ? 20  PRO B C   1 
ATOM 3360 O O   . PRO B 1 20  ? 34.333  91.507 29.150  1.00 0.58 ? 20  PRO B O   1 
ATOM 3361 C CB  . PRO B 1 20  ? 32.333  88.621 29.104  1.00 0.58 ? 20  PRO B CB  1 
ATOM 3362 C CG  . PRO B 1 20  ? 33.085  88.212 27.837  1.00 0.58 ? 20  PRO B CG  1 
ATOM 3363 C CD  . PRO B 1 20  ? 32.740  89.320 26.844  1.00 0.58 ? 20  PRO B CD  1 
ATOM 3364 N N   . SER B 1 21  ? 33.907  90.271 31.000  1.00 0.57 ? 21  SER B N   1 
ATOM 3365 C CA  . SER B 1 21  ? 35.037  90.715 31.813  1.00 0.57 ? 21  SER B CA  1 
ATOM 3366 C C   . SER B 1 21  ? 36.412  90.539 31.180  1.00 0.57 ? 21  SER B C   1 
ATOM 3367 O O   . SER B 1 21  ? 37.287  91.374 31.381  1.00 0.57 ? 21  SER B O   1 
ATOM 3368 C CB  . SER B 1 21  ? 35.093  90.008 33.205  1.00 0.57 ? 21  SER B CB  1 
ATOM 3369 O OG  . SER B 1 21  ? 33.829  89.968 33.888  1.00 0.57 ? 21  SER B OG  1 
ATOM 3370 N N   . ASP B 1 22  ? 36.606  89.463 30.388  1.00 0.54 ? 22  ASP B N   1 
ATOM 3371 C CA  . ASP B 1 22  ? 37.856  89.118 29.741  1.00 0.54 ? 22  ASP B CA  1 
ATOM 3372 C C   . ASP B 1 22  ? 37.696  89.372 28.245  1.00 0.54 ? 22  ASP B C   1 
ATOM 3373 O O   . ASP B 1 22  ? 36.627  89.166 27.673  1.00 0.54 ? 22  ASP B O   1 
ATOM 3374 C CB  . ASP B 1 22  ? 38.218  87.627 29.982  1.00 0.54 ? 22  ASP B CB  1 
ATOM 3375 C CG  . ASP B 1 22  ? 38.480  87.353 31.461  1.00 0.54 ? 22  ASP B CG  1 
ATOM 3376 O OD1 . ASP B 1 22  ? 38.666  88.324 32.236  1.00 0.54 ? 22  ASP B OD1 1 
ATOM 3377 O OD2 . ASP B 1 22  ? 38.441  86.155 31.838  1.00 0.54 ? 22  ASP B OD2 1 
ATOM 3378 N N   . SER B 1 23  ? 38.772  89.853 27.579  1.00 0.51 ? 23  SER B N   1 
ATOM 3379 C CA  . SER B 1 23  ? 38.758  90.297 26.181  1.00 0.51 ? 23  SER B CA  1 
ATOM 3380 C C   . SER B 1 23  ? 38.730  89.160 25.160  1.00 0.51 ? 23  SER B C   1 
ATOM 3381 O O   . SER B 1 23  ? 38.388  89.344 23.993  1.00 0.51 ? 23  SER B O   1 
ATOM 3382 C CB  . SER B 1 23  ? 39.977  91.230 25.897  1.00 0.51 ? 23  SER B CB  1 
ATOM 3383 O OG  . SER B 1 23  ? 39.851  91.965 24.677  1.00 0.51 ? 23  SER B OG  1 
ATOM 3384 N N   . THR B 1 24  ? 39.070  87.920 25.566  1.00 0.54 ? 24  THR B N   1 
ATOM 3385 C CA  . THR B 1 24  ? 39.050  86.751 24.690  1.00 0.54 ? 24  THR B CA  1 
ATOM 3386 C C   . THR B 1 24  ? 37.647  86.361 24.250  1.00 0.54 ? 24  THR B C   1 
ATOM 3387 O O   . THR B 1 24  ? 36.749  86.139 25.060  1.00 0.54 ? 24  THR B O   1 
ATOM 3388 C CB  . THR B 1 24  ? 39.742  85.545 25.303  1.00 0.54 ? 24  THR B CB  1 
ATOM 3389 O OG1 . THR B 1 24  ? 41.033  85.922 25.749  1.00 0.54 ? 24  THR B OG1 1 
ATOM 3390 C CG2 . THR B 1 24  ? 39.957  84.420 24.277  1.00 0.54 ? 24  THR B CG2 1 
ATOM 3391 N N   . GLY B 1 25  ? 37.398  86.280 22.924  1.00 0.55 ? 25  GLY B N   1 
ATOM 3392 C CA  . GLY B 1 25  ? 36.065  85.985 22.432  1.00 0.55 ? 25  GLY B CA  1 
ATOM 3393 C C   . GLY B 1 25  ? 36.051  85.884 20.936  1.00 0.55 ? 25  GLY B C   1 
ATOM 3394 O O   . GLY B 1 25  ? 37.026  86.208 20.264  1.00 0.55 ? 25  GLY B O   1 
ATOM 3395 N N   . SER B 1 26  ? 34.923  85.421 20.364  1.00 0.50 ? 26  SER B N   1 
ATOM 3396 C CA  . SER B 1 26  ? 34.810  85.068 18.951  1.00 0.50 ? 26  SER B CA  1 
ATOM 3397 C C   . SER B 1 26  ? 34.656  86.219 17.981  1.00 0.50 ? 26  SER B C   1 
ATOM 3398 O O   . SER B 1 26  ? 34.770  86.022 16.775  1.00 0.50 ? 26  SER B O   1 
ATOM 3399 C CB  . SER B 1 26  ? 33.603  84.135 18.677  1.00 0.50 ? 26  SER B CB  1 
ATOM 3400 O OG  . SER B 1 26  ? 33.613  83.032 19.582  1.00 0.50 ? 26  SER B OG  1 
ATOM 3401 N N   . ASN B 1 27  ? 34.353  87.444 18.472  1.00 0.45 ? 27  ASN B N   1 
ATOM 3402 C CA  . ASN B 1 27  ? 34.040  88.611 17.652  1.00 0.45 ? 27  ASN B CA  1 
ATOM 3403 C C   . ASN B 1 27  ? 32.861  88.342 16.705  1.00 0.45 ? 27  ASN B C   1 
ATOM 3404 O O   . ASN B 1 27  ? 32.944  88.498 15.489  1.00 0.45 ? 27  ASN B O   1 
ATOM 3405 C CB  . ASN B 1 27  ? 35.321  89.149 16.947  1.00 0.45 ? 27  ASN B CB  1 
ATOM 3406 C CG  . ASN B 1 27  ? 35.114  90.513 16.296  1.00 0.45 ? 27  ASN B CG  1 
ATOM 3407 O OD1 . ASN B 1 27  ? 34.395  91.373 16.807  1.00 0.45 ? 27  ASN B OD1 1 
ATOM 3408 N ND2 . ASN B 1 27  ? 35.771  90.733 15.132  1.00 0.45 ? 27  ASN B ND2 1 
ATOM 3409 N N   . GLN B 1 28  ? 31.707  87.905 17.265  1.00 0.45 ? 28  GLN B N   1 
ATOM 3410 C CA  . GLN B 1 28  ? 30.758  87.068 16.540  1.00 0.45 ? 28  GLN B CA  1 
ATOM 3411 C C   . GLN B 1 28  ? 29.824  87.846 15.613  1.00 0.45 ? 28  GLN B C   1 
ATOM 3412 O O   . GLN B 1 28  ? 28.971  87.298 14.921  1.00 0.45 ? 28  GLN B O   1 
ATOM 3413 C CB  . GLN B 1 28  ? 29.943  86.247 17.582  1.00 0.45 ? 28  GLN B CB  1 
ATOM 3414 C CG  . GLN B 1 28  ? 29.014  85.128 17.048  1.00 0.45 ? 28  GLN B CG  1 
ATOM 3415 C CD  . GLN B 1 28  ? 29.783  84.028 16.318  1.00 0.45 ? 28  GLN B CD  1 
ATOM 3416 O OE1 . GLN B 1 28  ? 30.979  83.815 16.529  1.00 0.45 ? 28  GLN B OE1 1 
ATOM 3417 N NE2 . GLN B 1 28  ? 29.063  83.271 15.458  1.00 0.45 ? 28  GLN B NE2 1 
ATOM 3418 N N   . ASN B 1 29  ? 30.002  89.179 15.538  1.00 0.43 ? 29  ASN B N   1 
ATOM 3419 C CA  . ASN B 1 29  ? 29.399  90.035 14.533  1.00 0.43 ? 29  ASN B CA  1 
ATOM 3420 C C   . ASN B 1 29  ? 29.800  89.700 13.092  1.00 0.43 ? 29  ASN B C   1 
ATOM 3421 O O   . ASN B 1 29  ? 28.983  89.863 12.185  1.00 0.43 ? 29  ASN B O   1 
ATOM 3422 C CB  . ASN B 1 29  ? 29.615  91.545 14.854  1.00 0.43 ? 29  ASN B CB  1 
ATOM 3423 C CG  . ASN B 1 29  ? 31.087  91.947 14.936  1.00 0.43 ? 29  ASN B CG  1 
ATOM 3424 O OD1 . ASN B 1 29  ? 31.691  92.310 13.929  1.00 0.43 ? 29  ASN B OD1 1 
ATOM 3425 N ND2 . ASN B 1 29  ? 31.665  91.939 16.155  1.00 0.43 ? 29  ASN B ND2 1 
ATOM 3426 N N   . GLY B 1 30  ? 31.050  89.227 12.860  1.00 0.49 ? 30  GLY B N   1 
ATOM 3427 C CA  . GLY B 1 30  ? 31.574  88.882 11.535  1.00 0.49 ? 30  GLY B CA  1 
ATOM 3428 C C   . GLY B 1 30  ? 31.589  90.026 10.557  1.00 0.49 ? 30  GLY B C   1 
ATOM 3429 O O   . GLY B 1 30  ? 32.288  91.017 10.740  1.00 0.49 ? 30  GLY B O   1 
ATOM 3430 N N   . GLU B 1 31  ? 30.793  89.926 9.483   1.00 0.42 ? 31  GLU B N   1 
ATOM 3431 C CA  . GLU B 1 31  ? 30.603  90.978 8.509   1.00 0.42 ? 31  GLU B CA  1 
ATOM 3432 C C   . GLU B 1 31  ? 29.723  92.118 9.016   1.00 0.42 ? 31  GLU B C   1 
ATOM 3433 O O   . GLU B 1 31  ? 29.664  93.188 8.418   1.00 0.42 ? 31  GLU B O   1 
ATOM 3434 C CB  . GLU B 1 31  ? 29.952  90.401 7.223   1.00 0.42 ? 31  GLU B CB  1 
ATOM 3435 C CG  . GLU B 1 31  ? 30.809  89.332 6.494   1.00 0.42 ? 31  GLU B CG  1 
ATOM 3436 C CD  . GLU B 1 31  ? 30.750  87.931 7.114   1.00 0.42 ? 31  GLU B CD  1 
ATOM 3437 O OE1 . GLU B 1 31  ? 30.004  87.738 8.112   1.00 0.42 ? 31  GLU B OE1 1 
ATOM 3438 O OE2 . GLU B 1 31  ? 31.465  87.048 6.583   1.00 0.42 ? 31  GLU B OE2 1 
ATOM 3439 N N   . ARG B 1 32  ? 28.991  91.897 10.129  1.00 0.37 ? 32  ARG B N   1 
ATOM 3440 C CA  . ARG B 1 32  ? 28.091  92.847 10.765  1.00 0.37 ? 32  ARG B CA  1 
ATOM 3441 C C   . ARG B 1 32  ? 26.939  93.315 9.880   1.00 0.37 ? 32  ARG B C   1 
ATOM 3442 O O   . ARG B 1 32  ? 26.486  94.455 9.928   1.00 0.37 ? 32  ARG B O   1 
ATOM 3443 C CB  . ARG B 1 32  ? 28.859  94.008 11.446  1.00 0.37 ? 32  ARG B CB  1 
ATOM 3444 C CG  . ARG B 1 32  ? 28.098  94.713 12.592  1.00 0.37 ? 32  ARG B CG  1 
ATOM 3445 C CD  . ARG B 1 32  ? 28.983  95.707 13.347  1.00 0.37 ? 32  ARG B CD  1 
ATOM 3446 N NE  . ARG B 1 32  ? 28.172  96.240 14.498  1.00 0.37 ? 32  ARG B NE  1 
ATOM 3447 C CZ  . ARG B 1 32  ? 28.698  96.727 15.630  1.00 0.37 ? 32  ARG B CZ  1 
ATOM 3448 N NH1 . ARG B 1 32  ? 27.902  97.152 16.610  1.00 0.37 ? 32  ARG B NH1 1 
ATOM 3449 N NH2 . ARG B 1 32  ? 30.011  96.789 15.810  1.00 0.37 ? 32  ARG B NH2 1 
ATOM 3450 N N   . SER B 1 33  ? 26.391  92.373 9.086   1.00 0.36 ? 33  SER B N   1 
ATOM 3451 C CA  . SER B 1 33  ? 25.245  92.560 8.198   1.00 0.36 ? 33  SER B CA  1 
ATOM 3452 C C   . SER B 1 33  ? 23.957  92.881 8.944   1.00 0.36 ? 33  SER B C   1 
ATOM 3453 O O   . SER B 1 33  ? 23.139  93.688 8.514   1.00 0.36 ? 33  SER B O   1 
ATOM 3454 C CB  . SER B 1 33  ? 25.074  91.314 7.280   1.00 0.36 ? 33  SER B CB  1 
ATOM 3455 O OG  . SER B 1 33  ? 24.007  91.452 6.339   1.00 0.36 ? 33  SER B OG  1 
ATOM 3456 N N   . GLY B 1 34  ? 23.749  92.262 10.129  1.00 0.37 ? 34  GLY B N   1 
ATOM 3457 C CA  . GLY B 1 34  ? 22.603  92.600 10.972  1.00 0.37 ? 34  GLY B CA  1 
ATOM 3458 C C   . GLY B 1 34  ? 21.294  91.976 10.577  1.00 0.37 ? 34  GLY B C   1 
ATOM 3459 O O   . GLY B 1 34  ? 20.238  92.415 11.010  1.00 0.37 ? 34  GLY B O   1 
ATOM 3460 N N   . ALA B 1 35  ? 21.338  90.915 9.757   1.00 0.29 ? 35  ALA B N   1 
ATOM 3461 C CA  . ALA B 1 35  ? 20.174  90.322 9.130   1.00 0.29 ? 35  ALA B CA  1 
ATOM 3462 C C   . ALA B 1 35  ? 19.263  89.494 10.039  1.00 0.29 ? 35  ALA B C   1 
ATOM 3463 O O   . ALA B 1 35  ? 18.145  89.143 9.671   1.00 0.29 ? 35  ALA B O   1 
ATOM 3464 C CB  . ALA B 1 35  ? 20.683  89.423 7.985   1.00 0.29 ? 35  ALA B CB  1 
ATOM 3465 N N   . ARG B 1 36  ? 19.736  89.117 11.244  1.00 0.23 ? 36  ARG B N   1 
ATOM 3466 C CA  . ARG B 1 36  ? 18.968  88.342 12.201  1.00 0.23 ? 36  ARG B CA  1 
ATOM 3467 C C   . ARG B 1 36  ? 17.737  89.026 12.783  1.00 0.23 ? 36  ARG B C   1 
ATOM 3468 O O   . ARG B 1 36  ? 17.733  90.212 13.101  1.00 0.23 ? 36  ARG B O   1 
ATOM 3469 C CB  . ARG B 1 36  ? 19.860  87.817 13.354  1.00 0.23 ? 36  ARG B CB  1 
ATOM 3470 C CG  . ARG B 1 36  ? 20.442  88.906 14.281  1.00 0.23 ? 36  ARG B CG  1 
ATOM 3471 C CD  . ARG B 1 36  ? 21.305  88.311 15.397  1.00 0.23 ? 36  ARG B CD  1 
ATOM 3472 N NE  . ARG B 1 36  ? 21.919  89.442 16.174  1.00 0.23 ? 36  ARG B NE  1 
ATOM 3473 C CZ  . ARG B 1 36  ? 21.358  90.035 17.239  1.00 0.23 ? 36  ARG B CZ  1 
ATOM 3474 N NH1 . ARG B 1 36  ? 21.987  91.064 17.811  1.00 0.23 ? 36  ARG B NH1 1 
ATOM 3475 N NH2 . ARG B 1 36  ? 20.194  89.642 17.739  1.00 0.23 ? 36  ARG B NH2 1 
ATOM 3476 N N   . SER B 1 37  ? 16.653  88.253 12.988  1.00 0.30 ? 37  SER B N   1 
ATOM 3477 C CA  . SER B 1 37  ? 15.361  88.797 13.378  1.00 0.30 ? 37  SER B CA  1 
ATOM 3478 C C   . SER B 1 37  ? 15.186  89.097 14.851  1.00 0.30 ? 37  SER B C   1 
ATOM 3479 O O   . SER B 1 37  ? 14.288  89.837 15.243  1.00 0.30 ? 37  SER B O   1 
ATOM 3480 C CB  . SER B 1 37  ? 14.236  87.789 13.042  1.00 0.30 ? 37  SER B CB  1 
ATOM 3481 O OG  . SER B 1 37  ? 14.368  87.336 11.697  1.00 0.30 ? 37  SER B OG  1 
ATOM 3482 N N   . LYS B 1 38  ? 16.007  88.493 15.732  1.00 0.46 ? 38  LYS B N   1 
ATOM 3483 C CA  . LYS B 1 38  ? 15.761  88.582 17.156  1.00 0.46 ? 38  LYS B CA  1 
ATOM 3484 C C   . LYS B 1 38  ? 17.027  88.252 17.946  1.00 0.46 ? 38  LYS B C   1 
ATOM 3485 O O   . LYS B 1 38  ? 18.019  87.752 17.413  1.00 0.46 ? 38  LYS B O   1 
ATOM 3486 C CB  . LYS B 1 38  ? 14.605  87.611 17.543  1.00 0.46 ? 38  LYS B CB  1 
ATOM 3487 C CG  . LYS B 1 38  ? 13.858  87.915 18.855  1.00 0.46 ? 38  LYS B CG  1 
ATOM 3488 C CD  . LYS B 1 38  ? 12.647  86.991 19.090  1.00 0.46 ? 38  LYS B CD  1 
ATOM 3489 C CE  . LYS B 1 38  ? 13.031  85.517 19.293  1.00 0.46 ? 38  LYS B CE  1 
ATOM 3490 N NZ  . LYS B 1 38  ? 11.824  84.676 19.467  1.00 0.46 ? 38  LYS B NZ  1 
ATOM 3491 N N   . GLN B 1 39  ? 17.030  88.552 19.263  1.00 0.51 ? 39  GLN B N   1 
ATOM 3492 C CA  . GLN B 1 39  ? 17.886  87.944 20.270  1.00 0.51 ? 39  GLN B CA  1 
ATOM 3493 C C   . GLN B 1 39  ? 17.430  86.521 20.613  1.00 0.51 ? 39  GLN B C   1 
ATOM 3494 O O   . GLN B 1 39  ? 16.370  86.080 20.170  1.00 0.51 ? 39  GLN B O   1 
ATOM 3495 C CB  . GLN B 1 39  ? 17.885  88.811 21.555  1.00 0.51 ? 39  GLN B CB  1 
ATOM 3496 C CG  . GLN B 1 39  ? 16.485  89.015 22.191  1.00 0.51 ? 39  GLN B CG  1 
ATOM 3497 C CD  . GLN B 1 39  ? 16.566  89.937 23.411  1.00 0.51 ? 39  GLN B CD  1 
ATOM 3498 O OE1 . GLN B 1 39  ? 17.628  90.144 24.002  1.00 0.51 ? 39  GLN B OE1 1 
ATOM 3499 N NE2 . GLN B 1 39  ? 15.406  90.516 23.794  1.00 0.51 ? 39  GLN B NE2 1 
ATOM 3500 N N   . ARG B 1 40  ? 18.224  85.760 21.409  1.00 0.38 ? 40  ARG B N   1 
ATOM 3501 C CA  . ARG B 1 40  ? 17.942  84.366 21.748  1.00 0.38 ? 40  ARG B CA  1 
ATOM 3502 C C   . ARG B 1 40  ? 16.608  84.145 22.462  1.00 0.38 ? 40  ARG B C   1 
ATOM 3503 O O   . ARG B 1 40  ? 15.792  83.329 22.035  1.00 0.38 ? 40  ARG B O   1 
ATOM 3504 C CB  . ARG B 1 40  ? 19.105  83.799 22.620  1.00 0.38 ? 40  ARG B CB  1 
ATOM 3505 C CG  . ARG B 1 40  ? 19.024  82.290 22.975  1.00 0.38 ? 40  ARG B CG  1 
ATOM 3506 C CD  . ARG B 1 40  ? 20.290  81.731 23.663  1.00 0.38 ? 40  ARG B CD  1 
ATOM 3507 N NE  . ARG B 1 40  ? 20.140  80.247 23.864  1.00 0.38 ? 40  ARG B NE  1 
ATOM 3508 C CZ  . ARG B 1 40  ? 20.277  79.316 22.909  1.00 0.38 ? 40  ARG B CZ  1 
ATOM 3509 N NH1 . ARG B 1 40  ? 20.081  78.039 23.223  1.00 0.38 ? 40  ARG B NH1 1 
ATOM 3510 N NH2 . ARG B 1 40  ? 20.594  79.627 21.657  1.00 0.38 ? 40  ARG B NH2 1 
ATOM 3511 N N   . ARG B 1 41  ? 16.316  84.926 23.520  1.00 0.38 ? 41  ARG B N   1 
ATOM 3512 C CA  . ARG B 1 41  ? 15.037  84.893 24.197  1.00 0.38 ? 41  ARG B CA  1 
ATOM 3513 C C   . ARG B 1 41  ? 14.772  86.299 24.722  1.00 0.38 ? 41  ARG B C   1 
ATOM 3514 O O   . ARG B 1 41  ? 15.742  87.021 24.955  1.00 0.38 ? 41  ARG B O   1 
ATOM 3515 C CB  . ARG B 1 41  ? 15.007  83.887 25.379  1.00 0.38 ? 41  ARG B CB  1 
ATOM 3516 C CG  . ARG B 1 41  ? 14.803  82.421 24.938  1.00 0.38 ? 41  ARG B CG  1 
ATOM 3517 C CD  . ARG B 1 41  ? 14.686  81.416 26.092  1.00 0.38 ? 41  ARG B CD  1 
ATOM 3518 N NE  . ARG B 1 41  ? 16.016  81.350 26.793  1.00 0.38 ? 41  ARG B NE  1 
ATOM 3519 C CZ  . ARG B 1 41  ? 17.020  80.502 26.528  1.00 0.38 ? 41  ARG B CZ  1 
ATOM 3520 N NH1 . ARG B 1 41  ? 18.154  80.593 27.211  1.00 0.38 ? 41  ARG B NH1 1 
ATOM 3521 N NH2 . ARG B 1 41  ? 16.931  79.543 25.614  1.00 0.38 ? 41  ARG B NH2 1 
ATOM 3522 N N   . PRO B 1 42  ? 13.533  86.767 24.874  1.00 0.47 ? 42  PRO B N   1 
ATOM 3523 C CA  . PRO B 1 42  ? 13.218  88.004 25.590  1.00 0.47 ? 42  PRO B CA  1 
ATOM 3524 C C   . PRO B 1 42  ? 13.676  88.097 27.039  1.00 0.47 ? 42  PRO B C   1 
ATOM 3525 O O   . PRO B 1 42  ? 13.795  87.080 27.720  1.00 0.47 ? 42  PRO B O   1 
ATOM 3526 C CB  . PRO B 1 42  ? 11.683  88.095 25.533  1.00 0.47 ? 42  PRO B CB  1 
ATOM 3527 C CG  . PRO B 1 42  ? 11.283  87.236 24.332  1.00 0.47 ? 42  PRO B CG  1 
ATOM 3528 C CD  . PRO B 1 42  ? 12.329  86.125 24.349  1.00 0.47 ? 42  PRO B CD  1 
ATOM 3529 N N   . GLN B 1 43  ? 13.890  89.331 27.534  1.00 0.45 ? 43  GLN B N   1 
ATOM 3530 C CA  . GLN B 1 43  ? 14.041  89.664 28.938  1.00 0.45 ? 43  GLN B CA  1 
ATOM 3531 C C   . GLN B 1 43  ? 12.786  89.367 29.758  1.00 0.45 ? 43  GLN B C   1 
ATOM 3532 O O   . GLN B 1 43  ? 11.664  89.402 29.259  1.00 0.45 ? 43  GLN B O   1 
ATOM 3533 C CB  . GLN B 1 43  ? 14.473  91.144 29.133  1.00 0.45 ? 43  GLN B CB  1 
ATOM 3534 C CG  . GLN B 1 43  ? 15.936  91.455 28.716  1.00 0.45 ? 43  GLN B CG  1 
ATOM 3535 C CD  . GLN B 1 43  ? 16.172  91.381 27.205  1.00 0.45 ? 43  GLN B CD  1 
ATOM 3536 O OE1 . GLN B 1 43  ? 15.289  91.653 26.388  1.00 0.45 ? 43  GLN B OE1 1 
ATOM 3537 N NE2 . GLN B 1 43  ? 17.400  90.968 26.810  1.00 0.45 ? 43  GLN B NE2 1 
ATOM 3538 N N   . GLY B 1 44  ? 12.963  89.045 31.059  1.00 0.40 ? 44  GLY B N   1 
ATOM 3539 C CA  . GLY B 1 44  ? 11.864  88.699 31.962  1.00 0.40 ? 44  GLY B CA  1 
ATOM 3540 C C   . GLY B 1 44  ? 11.656  87.222 32.155  1.00 0.40 ? 44  GLY B C   1 
ATOM 3541 O O   . GLY B 1 44  ? 10.835  86.803 32.964  1.00 0.40 ? 44  GLY B O   1 
ATOM 3542 N N   . LEU B 1 45  ? 12.410  86.380 31.434  1.00 0.34 ? 45  LEU B N   1 
ATOM 3543 C CA  . LEU B 1 45  ? 12.237  84.944 31.458  1.00 0.34 ? 45  LEU B CA  1 
ATOM 3544 C C   . LEU B 1 45  ? 13.367  84.284 32.254  1.00 0.34 ? 45  LEU B C   1 
ATOM 3545 O O   . LEU B 1 45  ? 14.523  84.688 32.092  1.00 0.34 ? 45  LEU B O   1 
ATOM 3546 C CB  . LEU B 1 45  ? 12.238  84.411 30.005  1.00 0.34 ? 45  LEU B CB  1 
ATOM 3547 C CG  . LEU B 1 45  ? 11.094  84.957 29.118  1.00 0.34 ? 45  LEU B CG  1 
ATOM 3548 C CD1 . LEU B 1 45  ? 11.291  84.519 27.658  1.00 0.34 ? 45  LEU B CD1 1 
ATOM 3549 C CD2 . LEU B 1 45  ? 9.702   84.529 29.613  1.00 0.34 ? 45  LEU B CD2 1 
ATOM 3550 N N   . PRO B 1 46  ? 13.141  83.310 33.151  1.00 0.53 ? 46  PRO B N   1 
ATOM 3551 C CA  . PRO B 1 46  ? 14.211  82.536 33.750  1.00 0.53 ? 46  PRO B CA  1 
ATOM 3552 C C   . PRO B 1 46  ? 14.850  81.622 32.751  1.00 0.53 ? 46  PRO B C   1 
ATOM 3553 O O   . PRO B 1 46  ? 14.308  81.401 31.669  1.00 0.53 ? 46  PRO B O   1 
ATOM 3554 C CB  . PRO B 1 46  ? 13.537  81.737 34.872  1.00 0.53 ? 46  PRO B CB  1 
ATOM 3555 C CG  . PRO B 1 46  ? 12.110  81.519 34.365  1.00 0.53 ? 46  PRO B CG  1 
ATOM 3556 C CD  . PRO B 1 46  ? 11.836  82.716 33.440  1.00 0.53 ? 46  PRO B CD  1 
ATOM 3557 N N   . ASN B 1 47  ? 16.028  81.090 33.106  1.00 0.52 ? 47  ASN B N   1 
ATOM 3558 C CA  . ASN B 1 47  ? 16.745  80.242 32.194  1.00 0.52 ? 47  ASN B CA  1 
ATOM 3559 C C   . ASN B 1 47  ? 16.781  78.852 32.761  1.00 0.52 ? 47  ASN B C   1 
ATOM 3560 O O   . ASN B 1 47  ? 16.688  77.893 31.998  1.00 0.52 ? 47  ASN B O   1 
ATOM 3561 C CB  . ASN B 1 47  ? 18.148  80.805 31.875  1.00 0.52 ? 47  ASN B CB  1 
ATOM 3562 C CG  . ASN B 1 47  ? 17.914  82.061 31.041  1.00 0.52 ? 47  ASN B CG  1 
ATOM 3563 O OD1 . ASN B 1 47  ? 17.939  82.009 29.808  1.00 0.52 ? 47  ASN B OD1 1 
ATOM 3564 N ND2 . ASN B 1 47  ? 17.634  83.198 31.712  1.00 0.52 ? 47  ASN B ND2 1 
ATOM 3565 N N   . ASN B 1 48  ? 16.867  78.700 34.109  1.00 0.53 ? 48  ASN B N   1 
ATOM 3566 C CA  . ASN B 1 48  ? 17.218  77.403 34.679  1.00 0.53 ? 48  ASN B CA  1 
ATOM 3567 C C   . ASN B 1 48  ? 16.961  77.252 36.232  1.00 0.53 ? 48  ASN B C   1 
ATOM 3568 O O   . ASN B 1 48  ? 16.513  78.239 36.821  1.00 0.53 ? 48  ASN B O   1 
ATOM 3569 C CB  . ASN B 1 48  ? 18.660  77.168 34.161  1.00 0.53 ? 48  ASN B CB  1 
ATOM 3570 C CG  . ASN B 1 48  ? 19.703  78.176 34.619  1.00 0.53 ? 48  ASN B CG  1 
ATOM 3571 O OD1 . ASN B 1 48  ? 19.556  78.977 35.538  1.00 0.53 ? 48  ASN B OD1 1 
ATOM 3572 N ND2 . ASN B 1 48  ? 20.870  78.142 33.917  1.00 0.53 ? 48  ASN B ND2 1 
ATOM 3573 N N   . THR B 1 49  ? 17.107  76.060 36.887  1.00 0.44 ? 49  THR B N   1 
ATOM 3574 C CA  . THR B 1 49  ? 16.964  75.861 38.397  1.00 0.44 ? 49  THR B CA  1 
ATOM 3575 C C   . THR B 1 49  ? 18.408  75.709 39.015  1.00 0.44 ? 49  THR B C   1 
ATOM 3576 O O   . THR B 1 49  ? 19.281  76.453 38.712  1.00 0.44 ? 49  THR B O   1 
ATOM 3577 C CB  . THR B 1 49  ? 16.026  74.734 38.851  1.00 0.44 ? 49  THR B CB  1 
ATOM 3578 O OG1 . THR B 1 49  ? 16.270  73.477 38.260  1.00 0.44 ? 49  THR B OG1 1 
ATOM 3579 C CG2 . THR B 1 49  ? 14.609  75.206 38.509  1.00 0.44 ? 49  THR B CG2 1 
ATOM 3580 N N   . ALA B 1 50  ? 18.749  74.755 39.922  1.00 0.45 ? 50  ALA B N   1 
ATOM 3581 C CA  . ALA B 1 50  ? 20.138  74.371 40.313  1.00 0.45 ? 50  ALA B CA  1 
ATOM 3582 C C   . ALA B 1 50  ? 20.751  73.195 39.513  1.00 0.45 ? 50  ALA B C   1 
ATOM 3583 O O   . ALA B 1 50  ? 20.029  72.378 38.961  1.00 0.45 ? 50  ALA B O   1 
ATOM 3584 C CB  . ALA B 1 50  ? 20.170  73.881 41.773  1.00 0.45 ? 50  ALA B CB  1 
ATOM 3585 N N   . SER B 1 51  ? 22.106  72.995 39.462  1.00 0.33 ? 51  SER B N   1 
ATOM 3586 C CA  . SER B 1 51  ? 22.774  71.810 38.870  1.00 0.33 ? 51  SER B CA  1 
ATOM 3587 C C   . SER B 1 51  ? 23.572  71.173 39.965  1.00 0.33 ? 51  SER B C   1 
ATOM 3588 O O   . SER B 1 51  ? 23.736  71.751 41.037  1.00 0.33 ? 51  SER B O   1 
ATOM 3589 C CB  . SER B 1 51  ? 23.776  72.076 37.695  1.00 0.33 ? 51  SER B CB  1 
ATOM 3590 O OG  . SER B 1 51  ? 24.482  70.959 37.153  1.00 0.33 ? 51  SER B OG  1 
ATOM 3591 N N   . TRP B 1 52  ? 24.084  69.957 39.726  1.00 0.38 ? 52  TRP B N   1 
ATOM 3592 C CA  . TRP B 1 52  ? 24.973  69.311 40.654  1.00 0.38 ? 52  TRP B CA  1 
ATOM 3593 C C   . TRP B 1 52  ? 26.394  69.382 40.139  1.00 0.38 ? 52  TRP B C   1 
ATOM 3594 O O   . TRP B 1 52  ? 26.694  68.925 39.035  1.00 0.38 ? 52  TRP B O   1 
ATOM 3595 C CB  . TRP B 1 52  ? 24.571  67.848 40.899  1.00 0.38 ? 52  TRP B CB  1 
ATOM 3596 C CG  . TRP B 1 52  ? 25.153  67.245 42.158  1.00 0.38 ? 52  TRP B CG  1 
ATOM 3597 C CD1 . TRP B 1 52  ? 26.456  66.942 42.451  1.00 0.38 ? 52  TRP B CD1 1 
ATOM 3598 C CD2 . TRP B 1 52  ? 24.404  66.948 43.346  1.00 0.38 ? 52  TRP B CD2 1 
ATOM 3599 N NE1 . TRP B 1 52  ? 26.535  66.314 43.670  1.00 0.38 ? 52  TRP B NE1 1 
ATOM 3600 C CE2 . TRP B 1 52  ? 25.298  66.343 44.245  1.00 0.38 ? 52  TRP B CE2 1 
ATOM 3601 C CE3 . TRP B 1 52  ? 23.074  67.174 43.702  1.00 0.38 ? 52  TRP B CE3 1 
ATOM 3602 C CZ2 . TRP B 1 52  ? 24.875  65.927 45.488  1.00 0.38 ? 52  TRP B CZ2 1 
ATOM 3603 C CZ3 . TRP B 1 52  ? 22.661  66.793 44.989  1.00 0.38 ? 52  TRP B CZ3 1 
ATOM 3604 C CH2 . TRP B 1 52  ? 23.551  66.166 45.868  1.00 0.38 ? 52  TRP B CH2 1 
ATOM 3605 N N   . PHE B 1 53  ? 27.292  69.930 40.972  1.00 0.55 ? 53  PHE B N   1 
ATOM 3606 C CA  . PHE B 1 53  ? 28.684  70.153 40.665  1.00 0.55 ? 53  PHE B CA  1 
ATOM 3607 C C   . PHE B 1 53  ? 29.526  69.471 41.728  1.00 0.55 ? 53  PHE B C   1 
ATOM 3608 O O   . PHE B 1 53  ? 29.047  69.130 42.808  1.00 0.55 ? 53  PHE B O   1 
ATOM 3609 C CB  . PHE B 1 53  ? 29.019  71.671 40.650  1.00 0.55 ? 53  PHE B CB  1 
ATOM 3610 C CG  . PHE B 1 53  ? 28.227  72.415 39.608  1.00 0.55 ? 53  PHE B CG  1 
ATOM 3611 C CD1 . PHE B 1 53  ? 28.476  72.183 38.249  1.00 0.55 ? 53  PHE B CD1 1 
ATOM 3612 C CD2 . PHE B 1 53  ? 27.271  73.385 39.960  1.00 0.55 ? 53  PHE B CD2 1 
ATOM 3613 C CE1 . PHE B 1 53  ? 27.779  72.885 37.258  1.00 0.55 ? 53  PHE B CE1 1 
ATOM 3614 C CE2 . PHE B 1 53  ? 26.586  74.105 38.973  1.00 0.55 ? 53  PHE B CE2 1 
ATOM 3615 C CZ  . PHE B 1 53  ? 26.838  73.850 37.620  1.00 0.55 ? 53  PHE B CZ  1 
ATOM 3616 N N   . THR B 1 54  ? 30.811  69.214 41.407  1.00 0.60 ? 54  THR B N   1 
ATOM 3617 C CA  . THR B 1 54  ? 31.805  68.609 42.295  1.00 0.60 ? 54  THR B CA  1 
ATOM 3618 C C   . THR B 1 54  ? 32.240  69.525 43.443  1.00 0.60 ? 54  THR B C   1 
ATOM 3619 O O   . THR B 1 54  ? 32.209  70.743 43.293  1.00 0.60 ? 54  THR B O   1 
ATOM 3620 C CB  . THR B 1 54  ? 33.057  68.169 41.533  1.00 0.60 ? 54  THR B CB  1 
ATOM 3621 O OG1 . THR B 1 54  ? 32.766  67.488 40.331  1.00 0.60 ? 54  THR B OG1 1 
ATOM 3622 C CG2 . THR B 1 54  ? 33.852  67.148 42.339  1.00 0.60 ? 54  THR B CG2 1 
ATOM 3623 N N   . ALA B 1 55  ? 32.649  68.994 44.628  1.00 0.60 ? 55  ALA B N   1 
ATOM 3624 C CA  . ALA B 1 55  ? 32.901  69.789 45.832  1.00 0.60 ? 55  ALA B CA  1 
ATOM 3625 C C   . ALA B 1 55  ? 34.246  69.550 46.539  1.00 0.60 ? 55  ALA B C   1 
ATOM 3626 O O   . ALA B 1 55  ? 34.608  68.421 46.853  1.00 0.60 ? 55  ALA B O   1 
ATOM 3627 C CB  . ALA B 1 55  ? 31.778  69.512 46.851  1.00 0.60 ? 55  ALA B CB  1 
ATOM 3628 N N   . LEU B 1 56  ? 34.982  70.644 46.847  1.00 0.62 ? 56  LEU B N   1 
ATOM 3629 C CA  . LEU B 1 56  ? 36.385  70.673 47.263  1.00 0.62 ? 56  LEU B CA  1 
ATOM 3630 C C   . LEU B 1 56  ? 36.528  71.197 48.699  1.00 0.62 ? 56  LEU B C   1 
ATOM 3631 O O   . LEU B 1 56  ? 35.637  71.884 49.192  1.00 0.62 ? 56  LEU B O   1 
ATOM 3632 C CB  . LEU B 1 56  ? 37.119  71.587 46.236  1.00 0.62 ? 56  LEU B CB  1 
ATOM 3633 C CG  . LEU B 1 56  ? 38.595  71.981 46.479  1.00 0.62 ? 56  LEU B CG  1 
ATOM 3634 C CD1 . LEU B 1 56  ? 39.329  72.097 45.136  1.00 0.62 ? 56  LEU B CD1 1 
ATOM 3635 C CD2 . LEU B 1 56  ? 38.768  73.307 47.251  1.00 0.62 ? 56  LEU B CD2 1 
ATOM 3636 N N   . THR B 1 57  ? 37.635  70.887 49.424  1.00 0.61 ? 57  THR B N   1 
ATOM 3637 C CA  . THR B 1 57  ? 37.829  71.331 50.819  1.00 0.61 ? 57  THR B CA  1 
ATOM 3638 C C   . THR B 1 57  ? 39.309  71.569 51.096  1.00 0.61 ? 57  THR B C   1 
ATOM 3639 O O   . THR B 1 57  ? 40.173  70.802 50.684  1.00 0.61 ? 57  THR B O   1 
ATOM 3640 C CB  . THR B 1 57  ? 37.281  70.339 51.858  1.00 0.61 ? 57  THR B CB  1 
ATOM 3641 O OG1 . THR B 1 57  ? 35.863  70.302 51.820  1.00 0.61 ? 57  THR B OG1 1 
ATOM 3642 C CG2 . THR B 1 57  ? 37.624  70.687 53.316  1.00 0.61 ? 57  THR B CG2 1 
ATOM 3643 N N   . GLN B 1 58  ? 39.677  72.662 51.802  1.00 0.57 ? 58  GLN B N   1 
ATOM 3644 C CA  . GLN B 1 58  ? 41.075  73.031 52.011  1.00 0.57 ? 58  GLN B CA  1 
ATOM 3645 C C   . GLN B 1 58  ? 41.900  72.326 53.080  1.00 0.57 ? 58  GLN B C   1 
ATOM 3646 O O   . GLN B 1 58  ? 43.068  72.067 52.828  1.00 0.57 ? 58  GLN B O   1 
ATOM 3647 C CB  . GLN B 1 58  ? 41.229  74.543 52.268  1.00 0.57 ? 58  GLN B CB  1 
ATOM 3648 C CG  . GLN B 1 58  ? 41.140  75.376 50.983  1.00 0.57 ? 58  GLN B CG  1 
ATOM 3649 C CD  . GLN B 1 58  ? 41.959  76.651 51.140  1.00 0.57 ? 58  GLN B CD  1 
ATOM 3650 O OE1 . GLN B 1 58  ? 41.451  77.747 51.384  1.00 0.57 ? 58  GLN B OE1 1 
ATOM 3651 N NE2 . GLN B 1 58  ? 43.293  76.491 51.008  1.00 0.57 ? 58  GLN B NE2 1 
ATOM 3652 N N   . HIS B 1 59  ? 41.369  72.093 54.301  1.00 0.52 ? 59  HIS B N   1 
ATOM 3653 C CA  . HIS B 1 59  ? 42.156  71.669 55.464  1.00 0.52 ? 59  HIS B CA  1 
ATOM 3654 C C   . HIS B 1 59  ? 43.291  72.646 55.807  1.00 0.52 ? 59  HIS B C   1 
ATOM 3655 O O   . HIS B 1 59  ? 44.408  72.249 56.131  1.00 0.52 ? 59  HIS B O   1 
ATOM 3656 C CB  . HIS B 1 59  ? 42.710  70.233 55.312  1.00 0.52 ? 59  HIS B CB  1 
ATOM 3657 C CG  . HIS B 1 59  ? 41.681  69.196 54.967  1.00 0.52 ? 59  HIS B CG  1 
ATOM 3658 N ND1 . HIS B 1 59  ? 41.390  68.250 55.918  1.00 0.52 ? 59  HIS B ND1 1 
ATOM 3659 C CD2 . HIS B 1 59  ? 41.012  68.908 53.817  1.00 0.52 ? 59  HIS B CD2 1 
ATOM 3660 C CE1 . HIS B 1 59  ? 40.574  67.403 55.352  1.00 0.52 ? 59  HIS B CE1 1 
ATOM 3661 N NE2 . HIS B 1 59  ? 40.300  67.752 54.074  1.00 0.52 ? 59  HIS B NE2 1 
ATOM 3662 N N   . GLY B 1 60  ? 43.040  73.971 55.702  1.00 0.54 ? 60  GLY B N   1 
ATOM 3663 C CA  . GLY B 1 60  ? 44.108  74.953 55.837  1.00 0.54 ? 60  GLY B CA  1 
ATOM 3664 C C   . GLY B 1 60  ? 43.727  76.328 55.348  1.00 0.54 ? 60  GLY B C   1 
ATOM 3665 O O   . GLY B 1 60  ? 42.548  76.677 55.274  1.00 0.54 ? 60  GLY B O   1 
ATOM 3666 N N   . LYS B 1 61  ? 44.739  77.161 54.989  1.00 0.54 ? 61  LYS B N   1 
ATOM 3667 C CA  . LYS B 1 61  ? 44.544  78.582 54.742  1.00 0.54 ? 61  LYS B CA  1 
ATOM 3668 C C   . LYS B 1 61  ? 45.362  79.153 53.586  1.00 0.54 ? 61  LYS B C   1 
ATOM 3669 O O   . LYS B 1 61  ? 45.426  80.368 53.423  1.00 0.54 ? 61  LYS B O   1 
ATOM 3670 C CB  . LYS B 1 61  ? 44.933  79.385 56.018  1.00 0.54 ? 61  LYS B CB  1 
ATOM 3671 C CG  . LYS B 1 61  ? 46.419  79.286 56.429  1.00 0.54 ? 61  LYS B CG  1 
ATOM 3672 C CD  . LYS B 1 61  ? 46.748  80.004 57.754  1.00 0.54 ? 61  LYS B CD  1 
ATOM 3673 C CE  . LYS B 1 61  ? 46.595  81.530 57.697  1.00 0.54 ? 61  LYS B CE  1 
ATOM 3674 N NZ  . LYS B 1 61  ? 46.988  82.143 58.989  1.00 0.54 ? 61  LYS B NZ  1 
ATOM 3675 N N   . GLU B 1 62  ? 46.011  78.298 52.767  1.00 0.55 ? 62  GLU B N   1 
ATOM 3676 C CA  . GLU B 1 62  ? 46.748  78.676 51.565  1.00 0.55 ? 62  GLU B CA  1 
ATOM 3677 C C   . GLU B 1 62  ? 45.848  79.116 50.410  1.00 0.55 ? 62  GLU B C   1 
ATOM 3678 O O   . GLU B 1 62  ? 44.701  78.688 50.314  1.00 0.55 ? 62  GLU B O   1 
ATOM 3679 C CB  . GLU B 1 62  ? 47.663  77.502 51.143  1.00 0.55 ? 62  GLU B CB  1 
ATOM 3680 C CG  . GLU B 1 62  ? 48.627  77.796 49.969  1.00 0.55 ? 62  GLU B CG  1 
ATOM 3681 C CD  . GLU B 1 62  ? 49.781  76.798 49.910  1.00 0.55 ? 62  GLU B CD  1 
ATOM 3682 O OE1 . GLU B 1 62  ? 49.595  75.636 50.361  1.00 0.55 ? 62  GLU B OE1 1 
ATOM 3683 O OE2 . GLU B 1 62  ? 50.859  77.197 49.404  1.00 0.55 ? 62  GLU B OE2 1 
ATOM 3684 N N   . ASP B 1 63  ? 46.312  79.998 49.499  1.00 0.51 ? 63  ASP B N   1 
ATOM 3685 C CA  . ASP B 1 63  ? 45.525  80.438 48.360  1.00 0.51 ? 63  ASP B CA  1 
ATOM 3686 C C   . ASP B 1 63  ? 45.167  79.318 47.375  1.00 0.51 ? 63  ASP B C   1 
ATOM 3687 O O   . ASP B 1 63  ? 46.006  78.531 46.943  1.00 0.51 ? 63  ASP B O   1 
ATOM 3688 C CB  . ASP B 1 63  ? 46.235  81.536 47.525  1.00 0.51 ? 63  ASP B CB  1 
ATOM 3689 C CG  . ASP B 1 63  ? 46.452  82.861 48.246  1.00 0.51 ? 63  ASP B CG  1 
ATOM 3690 O OD1 . ASP B 1 63  ? 46.005  83.053 49.394  1.00 0.51 ? 63  ASP B OD1 1 
ATOM 3691 O OD2 . ASP B 1 63  ? 47.055  83.739 47.567  1.00 0.51 ? 63  ASP B OD2 1 
ATOM 3692 N N   . LEU B 1 64  ? 43.893  79.258 46.926  1.00 0.57 ? 64  LEU B N   1 
ATOM 3693 C CA  . LEU B 1 64  ? 43.488  78.406 45.815  1.00 0.57 ? 64  LEU B CA  1 
ATOM 3694 C C   . LEU B 1 64  ? 43.910  79.032 44.480  1.00 0.57 ? 64  LEU B C   1 
ATOM 3695 O O   . LEU B 1 64  ? 43.153  79.763 43.844  1.00 0.57 ? 64  LEU B O   1 
ATOM 3696 C CB  . LEU B 1 64  ? 41.954  78.168 45.837  1.00 0.57 ? 64  LEU B CB  1 
ATOM 3697 C CG  . LEU B 1 64  ? 41.418  77.152 44.800  1.00 0.57 ? 64  LEU B CG  1 
ATOM 3698 C CD1 . LEU B 1 64  ? 41.530  75.703 45.278  1.00 0.57 ? 64  LEU B CD1 1 
ATOM 3699 C CD2 . LEU B 1 64  ? 39.956  77.420 44.442  1.00 0.57 ? 64  LEU B CD2 1 
ATOM 3700 N N   . LYS B 1 65  ? 45.161  78.785 44.042  1.00 0.52 ? 65  LYS B N   1 
ATOM 3701 C CA  . LYS B 1 65  ? 45.743  79.415 42.870  1.00 0.52 ? 65  LYS B CA  1 
ATOM 3702 C C   . LYS B 1 65  ? 46.508  78.417 42.025  1.00 0.52 ? 65  LYS B C   1 
ATOM 3703 O O   . LYS B 1 65  ? 46.904  77.352 42.489  1.00 0.52 ? 65  LYS B O   1 
ATOM 3704 C CB  . LYS B 1 65  ? 46.695  80.565 43.287  1.00 0.52 ? 65  LYS B CB  1 
ATOM 3705 C CG  . LYS B 1 65  ? 45.939  81.849 43.656  1.00 0.52 ? 65  LYS B CG  1 
ATOM 3706 C CD  . LYS B 1 65  ? 46.860  82.954 44.197  1.00 0.52 ? 65  LYS B CD  1 
ATOM 3707 C CE  . LYS B 1 65  ? 46.078  84.213 44.600  1.00 0.52 ? 65  LYS B CE  1 
ATOM 3708 N NZ  . LYS B 1 65  ? 46.912  85.105 45.427  1.00 0.52 ? 65  LYS B NZ  1 
ATOM 3709 N N   . PHE B 1 66  ? 46.721  78.761 40.736  1.00 0.46 ? 66  PHE B N   1 
ATOM 3710 C CA  . PHE B 1 66  ? 47.256  77.863 39.735  1.00 0.46 ? 66  PHE B CA  1 
ATOM 3711 C C   . PHE B 1 66  ? 48.160  78.663 38.793  1.00 0.46 ? 66  PHE B C   1 
ATOM 3712 O O   . PHE B 1 66  ? 48.048  79.892 38.764  1.00 0.46 ? 66  PHE B O   1 
ATOM 3713 C CB  . PHE B 1 66  ? 46.116  77.267 38.868  1.00 0.46 ? 66  PHE B CB  1 
ATOM 3714 C CG  . PHE B 1 66  ? 45.161  76.407 39.650  1.00 0.46 ? 66  PHE B CG  1 
ATOM 3715 C CD1 . PHE B 1 66  ? 45.392  75.030 39.780  1.00 0.46 ? 66  PHE B CD1 1 
ATOM 3716 C CD2 . PHE B 1 66  ? 43.984  76.950 40.193  1.00 0.46 ? 66  PHE B CD2 1 
ATOM 3717 C CE1 . PHE B 1 66  ? 44.461  74.209 40.424  1.00 0.46 ? 66  PHE B CE1 1 
ATOM 3718 C CE2 . PHE B 1 66  ? 43.058  76.134 40.854  1.00 0.46 ? 66  PHE B CE2 1 
ATOM 3719 C CZ  . PHE B 1 66  ? 43.292  74.759 40.958  1.00 0.46 ? 66  PHE B CZ  1 
ATOM 3720 N N   . PRO B 1 67  ? 49.061  78.058 38.013  1.00 0.44 ? 67  PRO B N   1 
ATOM 3721 C CA  . PRO B 1 67  ? 49.663  78.655 36.815  1.00 0.44 ? 67  PRO B CA  1 
ATOM 3722 C C   . PRO B 1 67  ? 48.701  79.202 35.763  1.00 0.44 ? 67  PRO B C   1 
ATOM 3723 O O   . PRO B 1 67  ? 47.489  79.028 35.849  1.00 0.44 ? 67  PRO B O   1 
ATOM 3724 C CB  . PRO B 1 67  ? 50.531  77.526 36.226  1.00 0.44 ? 67  PRO B CB  1 
ATOM 3725 C CG  . PRO B 1 67  ? 50.797  76.588 37.403  1.00 0.44 ? 67  PRO B CG  1 
ATOM 3726 C CD  . PRO B 1 67  ? 49.500  76.677 38.198  1.00 0.44 ? 67  PRO B CD  1 
ATOM 3727 N N   . ARG B 1 68  ? 49.239  79.876 34.720  1.00 0.44 ? 68  ARG B N   1 
ATOM 3728 C CA  . ARG B 1 68  ? 48.461  80.422 33.614  1.00 0.44 ? 68  ARG B CA  1 
ATOM 3729 C C   . ARG B 1 68  ? 47.722  79.372 32.777  1.00 0.44 ? 68  ARG B C   1 
ATOM 3730 O O   . ARG B 1 68  ? 46.606  79.597 32.310  1.00 0.44 ? 68  ARG B O   1 
ATOM 3731 C CB  . ARG B 1 68  ? 49.357  81.307 32.700  1.00 0.44 ? 68  ARG B CB  1 
ATOM 3732 C CG  . ARG B 1 68  ? 50.118  82.445 33.426  1.00 0.44 ? 68  ARG B CG  1 
ATOM 3733 C CD  . ARG B 1 68  ? 49.261  83.422 34.253  1.00 0.44 ? 68  ARG B CD  1 
ATOM 3734 N NE  . ARG B 1 68  ? 48.343  84.156 33.309  1.00 0.44 ? 68  ARG B NE  1 
ATOM 3735 C CZ  . ARG B 1 68  ? 47.135  84.656 33.623  1.00 0.44 ? 68  ARG B CZ  1 
ATOM 3736 N NH1 . ARG B 1 68  ? 46.437  85.341 32.716  1.00 0.44 ? 68  ARG B NH1 1 
ATOM 3737 N NH2 . ARG B 1 68  ? 46.608  84.474 34.829  1.00 0.44 ? 68  ARG B NH2 1 
ATOM 3738 N N   . GLY B 1 69  ? 48.341  78.193 32.565  1.00 0.53 ? 69  GLY B N   1 
ATOM 3739 C CA  . GLY B 1 69  ? 47.704  77.052 31.920  1.00 0.53 ? 69  GLY B CA  1 
ATOM 3740 C C   . GLY B 1 69  ? 47.077  76.124 32.925  1.00 0.53 ? 69  GLY B C   1 
ATOM 3741 O O   . GLY B 1 69  ? 47.563  75.986 34.042  1.00 0.53 ? 69  GLY B O   1 
ATOM 3742 N N   . GLN B 1 70  ? 45.976  75.452 32.521  1.00 0.55 ? 70  GLN B N   1 
ATOM 3743 C CA  . GLN B 1 70  ? 45.244  74.458 33.301  1.00 0.55 ? 70  GLN B CA  1 
ATOM 3744 C C   . GLN B 1 70  ? 44.668  74.952 34.626  1.00 0.55 ? 70  GLN B C   1 
ATOM 3745 O O   . GLN B 1 70  ? 44.394  74.179 35.538  1.00 0.55 ? 70  GLN B O   1 
ATOM 3746 C CB  . GLN B 1 70  ? 46.042  73.140 33.455  1.00 0.55 ? 70  GLN B CB  1 
ATOM 3747 C CG  . GLN B 1 70  ? 46.328  72.466 32.092  1.00 0.55 ? 70  GLN B CG  1 
ATOM 3748 C CD  . GLN B 1 70  ? 47.067  71.134 32.241  1.00 0.55 ? 70  GLN B CD  1 
ATOM 3749 O OE1 . GLN B 1 70  ? 47.524  70.768 33.321  1.00 0.55 ? 70  GLN B OE1 1 
ATOM 3750 N NE2 . GLN B 1 70  ? 47.209  70.411 31.105  1.00 0.55 ? 70  GLN B NE2 1 
ATOM 3751 N N   . GLY B 1 71  ? 44.388  76.268 34.726  1.00 0.57 ? 71  GLY B N   1 
ATOM 3752 C CA  . GLY B 1 71  ? 43.915  76.900 35.956  1.00 0.57 ? 71  GLY B CA  1 
ATOM 3753 C C   . GLY B 1 71  ? 42.463  76.723 36.301  1.00 0.57 ? 71  GLY B C   1 
ATOM 3754 O O   . GLY B 1 71  ? 42.008  77.201 37.335  1.00 0.57 ? 71  GLY B O   1 
ATOM 3755 N N   . VAL B 1 72  ? 41.686  76.038 35.449  1.00 0.66 ? 72  VAL B N   1 
ATOM 3756 C CA  . VAL B 1 72  ? 40.296  75.722 35.731  1.00 0.66 ? 72  VAL B CA  1 
ATOM 3757 C C   . VAL B 1 72  ? 39.969  74.388 35.045  1.00 0.66 ? 72  VAL B C   1 
ATOM 3758 O O   . VAL B 1 72  ? 40.574  74.124 34.002  1.00 0.66 ? 72  VAL B O   1 
ATOM 3759 C CB  . VAL B 1 72  ? 39.349  76.855 35.310  1.00 0.66 ? 72  VAL B CB  1 
ATOM 3760 C CG1 . VAL B 1 72  ? 39.325  77.057 33.778  1.00 0.66 ? 72  VAL B CG1 1 
ATOM 3761 C CG2 . VAL B 1 72  ? 37.935  76.645 35.881  1.00 0.66 ? 72  VAL B CG2 1 
ATOM 3762 N N   . PRO B 1 73  ? 39.099  73.490 35.537  1.00 0.65 ? 73  PRO B N   1 
ATOM 3763 C CA  . PRO B 1 73  ? 38.857  72.196 34.896  1.00 0.65 ? 73  PRO B CA  1 
ATOM 3764 C C   . PRO B 1 73  ? 38.065  72.227 33.595  1.00 0.65 ? 73  PRO B C   1 
ATOM 3765 O O   . PRO B 1 73  ? 37.170  73.059 33.435  1.00 0.65 ? 73  PRO B O   1 
ATOM 3766 C CB  . PRO B 1 73  ? 38.051  71.397 35.936  1.00 0.65 ? 73  PRO B CB  1 
ATOM 3767 C CG  . PRO B 1 73  ? 38.424  72.024 37.274  1.00 0.65 ? 73  PRO B CG  1 
ATOM 3768 C CD  . PRO B 1 73  ? 38.592  73.496 36.913  1.00 0.65 ? 73  PRO B CD  1 
ATOM 3769 N N   . ILE B 1 74  ? 38.361  71.283 32.675  1.00 0.58 ? 74  ILE B N   1 
ATOM 3770 C CA  . ILE B 1 74  ? 37.617  71.020 31.447  1.00 0.58 ? 74  ILE B CA  1 
ATOM 3771 C C   . ILE B 1 74  ? 37.402  69.509 31.405  1.00 0.58 ? 74  ILE B C   1 
ATOM 3772 O O   . ILE B 1 74  ? 38.349  68.746 31.596  1.00 0.58 ? 74  ILE B O   1 
ATOM 3773 C CB  . ILE B 1 74  ? 38.384  71.462 30.195  1.00 0.58 ? 74  ILE B CB  1 
ATOM 3774 C CG1 . ILE B 1 74  ? 38.571  73.000 30.135  1.00 0.58 ? 74  ILE B CG1 1 
ATOM 3775 C CG2 . ILE B 1 74  ? 37.724  70.933 28.898  1.00 0.58 ? 74  ILE B CG2 1 
ATOM 3776 C CD1 . ILE B 1 74  ? 37.285  73.793 29.881  1.00 0.58 ? 74  ILE B CD1 1 
ATOM 3777 N N   . ASN B 1 75  ? 36.163  69.013 31.168  1.00 0.49 ? 75  ASN B N   1 
ATOM 3778 C CA  . ASN B 1 75  ? 35.853  67.595 31.137  1.00 0.49 ? 75  ASN B CA  1 
ATOM 3779 C C   . ASN B 1 75  ? 34.736  67.386 30.114  1.00 0.49 ? 75  ASN B C   1 
ATOM 3780 O O   . ASN B 1 75  ? 34.052  68.331 29.742  1.00 0.49 ? 75  ASN B O   1 
ATOM 3781 C CB  . ASN B 1 75  ? 35.401  67.058 32.531  1.00 0.49 ? 75  ASN B CB  1 
ATOM 3782 C CG  . ASN B 1 75  ? 36.550  67.031 33.533  1.00 0.49 ? 75  ASN B CG  1 
ATOM 3783 O OD1 . ASN B 1 75  ? 36.610  67.796 34.495  1.00 0.49 ? 75  ASN B OD1 1 
ATOM 3784 N ND2 . ASN B 1 75  ? 37.514  66.098 33.342  1.00 0.49 ? 75  ASN B ND2 1 
ATOM 3785 N N   . THR B 1 76  ? 34.502  66.138 29.624  1.00 0.43 ? 76  THR B N   1 
ATOM 3786 C CA  . THR B 1 76  ? 33.608  65.832 28.482  1.00 0.43 ? 76  THR B CA  1 
ATOM 3787 C C   . THR B 1 76  ? 32.194  66.390 28.563  1.00 0.43 ? 76  THR B C   1 
ATOM 3788 O O   . THR B 1 76  ? 31.627  66.803 27.555  1.00 0.43 ? 76  THR B O   1 
ATOM 3789 C CB  . THR B 1 76  ? 33.490  64.312 28.231  1.00 0.43 ? 76  THR B CB  1 
ATOM 3790 O OG1 . THR B 1 76  ? 34.660  63.764 27.636  1.00 0.43 ? 76  THR B OG1 1 
ATOM 3791 C CG2 . THR B 1 76  ? 32.375  63.874 27.266  1.00 0.43 ? 76  THR B CG2 1 
ATOM 3792 N N   . ASN B 1 77  ? 31.566  66.417 29.752  1.00 0.56 ? 77  ASN B N   1 
ATOM 3793 C CA  . ASN B 1 77  ? 30.226  66.953 29.907  1.00 0.56 ? 77  ASN B CA  1 
ATOM 3794 C C   . ASN B 1 77  ? 30.180  68.373 30.460  1.00 0.56 ? 77  ASN B C   1 
ATOM 3795 O O   . ASN B 1 77  ? 29.090  68.917 30.617  1.00 0.56 ? 77  ASN B O   1 
ATOM 3796 C CB  . ASN B 1 77  ? 29.429  66.055 30.883  1.00 0.56 ? 77  ASN B CB  1 
ATOM 3797 C CG  . ASN B 1 77  ? 29.172  64.697 30.250  1.00 0.56 ? 77  ASN B CG  1 
ATOM 3798 O OD1 . ASN B 1 77  ? 29.777  63.669 30.564  1.00 0.56 ? 77  ASN B OD1 1 
ATOM 3799 N ND2 . ASN B 1 77  ? 28.221  64.672 29.290  1.00 0.56 ? 77  ASN B ND2 1 
ATOM 3800 N N   . SER B 1 78  ? 31.324  69.016 30.787  1.00 0.62 ? 78  SER B N   1 
ATOM 3801 C CA  . SER B 1 78  ? 31.305  70.311 31.458  1.00 0.62 ? 78  SER B CA  1 
ATOM 3802 C C   . SER B 1 78  ? 30.917  71.492 30.587  1.00 0.62 ? 78  SER B C   1 
ATOM 3803 O O   . SER B 1 78  ? 30.118  72.338 30.987  1.00 0.62 ? 78  SER B O   1 
ATOM 3804 C CB  . SER B 1 78  ? 32.627  70.632 32.228  1.00 0.62 ? 78  SER B CB  1 
ATOM 3805 O OG  . SER B 1 78  ? 33.790  70.688 31.402  1.00 0.62 ? 78  SER B OG  1 
ATOM 3806 N N   . SER B 1 79  ? 31.475  71.606 29.369  1.00 0.57 ? 79  SER B N   1 
ATOM 3807 C CA  . SER B 1 79  ? 31.429  72.872 28.666  1.00 0.57 ? 79  SER B CA  1 
ATOM 3808 C C   . SER B 1 79  ? 31.916  72.707 27.231  1.00 0.57 ? 79  SER B C   1 
ATOM 3809 O O   . SER B 1 79  ? 32.542  71.693 26.935  1.00 0.57 ? 79  SER B O   1 
ATOM 3810 C CB  . SER B 1 79  ? 32.245  73.951 29.435  1.00 0.57 ? 79  SER B CB  1 
ATOM 3811 O OG  . SER B 1 79  ? 33.500  73.466 29.913  1.00 0.57 ? 79  SER B OG  1 
ATOM 3812 N N   . PRO B 1 80  ? 31.663  73.612 26.277  1.00 0.39 ? 80  PRO B N   1 
ATOM 3813 C CA  . PRO B 1 80  ? 31.996  73.370 24.869  1.00 0.39 ? 80  PRO B CA  1 
ATOM 3814 C C   . PRO B 1 80  ? 33.404  73.861 24.546  1.00 0.39 ? 80  PRO B C   1 
ATOM 3815 O O   . PRO B 1 80  ? 33.548  74.863 23.849  1.00 0.39 ? 80  PRO B O   1 
ATOM 3816 C CB  . PRO B 1 80  ? 30.939  74.222 24.124  1.00 0.39 ? 80  PRO B CB  1 
ATOM 3817 C CG  . PRO B 1 80  ? 30.664  75.397 25.069  1.00 0.39 ? 80  PRO B CG  1 
ATOM 3818 C CD  . PRO B 1 80  ? 30.768  74.758 26.449  1.00 0.39 ? 80  PRO B CD  1 
ATOM 3819 N N   . ASP B 1 81  ? 34.442  73.174 25.069  1.00 0.49 ? 81  ASP B N   1 
ATOM 3820 C CA  . ASP B 1 81  ? 35.858  73.497 24.929  1.00 0.49 ? 81  ASP B CA  1 
ATOM 3821 C C   . ASP B 1 81  ? 36.185  74.926 25.388  1.00 0.49 ? 81  ASP B C   1 
ATOM 3822 O O   . ASP B 1 81  ? 36.996  75.646 24.809  1.00 0.49 ? 81  ASP B O   1 
ATOM 3823 C CB  . ASP B 1 81  ? 36.406  73.146 23.515  1.00 0.49 ? 81  ASP B CB  1 
ATOM 3824 C CG  . ASP B 1 81  ? 36.195  71.677 23.167  1.00 0.49 ? 81  ASP B CG  1 
ATOM 3825 O OD1 . ASP B 1 81  ? 35.959  70.861 24.096  1.00 0.49 ? 81  ASP B OD1 1 
ATOM 3826 O OD2 . ASP B 1 81  ? 36.297  71.353 21.956  1.00 0.49 ? 81  ASP B OD2 1 
ATOM 3827 N N   . ASP B 1 82  ? 35.543  75.349 26.497  1.00 0.52 ? 82  ASP B N   1 
ATOM 3828 C CA  . ASP B 1 82  ? 35.474  76.724 26.927  1.00 0.52 ? 82  ASP B CA  1 
ATOM 3829 C C   . ASP B 1 82  ? 35.138  76.693 28.418  1.00 0.52 ? 82  ASP B C   1 
ATOM 3830 O O   . ASP B 1 82  ? 34.791  75.636 28.949  1.00 0.52 ? 82  ASP B O   1 
ATOM 3831 C CB  . ASP B 1 82  ? 34.377  77.456 26.107  1.00 0.52 ? 82  ASP B CB  1 
ATOM 3832 C CG  . ASP B 1 82  ? 34.384  78.952 26.329  1.00 0.52 ? 82  ASP B CG  1 
ATOM 3833 O OD1 . ASP B 1 82  ? 35.311  79.464 27.010  1.00 0.52 ? 82  ASP B OD1 1 
ATOM 3834 O OD2 . ASP B 1 82  ? 33.463  79.624 25.814  1.00 0.52 ? 82  ASP B OD2 1 
ATOM 3835 N N   . GLN B 1 83  ? 35.225  77.813 29.161  1.00 0.62 ? 83  GLN B N   1 
ATOM 3836 C CA  . GLN B 1 83  ? 34.838  77.801 30.558  1.00 0.62 ? 83  GLN B CA  1 
ATOM 3837 C C   . GLN B 1 83  ? 34.442  79.158 31.118  1.00 0.62 ? 83  GLN B C   1 
ATOM 3838 O O   . GLN B 1 83  ? 35.240  80.085 31.137  1.00 0.62 ? 83  GLN B O   1 
ATOM 3839 C CB  . GLN B 1 83  ? 35.968  77.201 31.443  1.00 0.62 ? 83  GLN B CB  1 
ATOM 3840 C CG  . GLN B 1 83  ? 35.578  76.886 32.903  1.00 0.62 ? 83  GLN B CG  1 
ATOM 3841 C CD  . GLN B 1 83  ? 34.414  75.900 32.968  1.00 0.62 ? 83  GLN B CD  1 
ATOM 3842 O OE1 . GLN B 1 83  ? 33.246  76.265 32.790  1.00 0.62 ? 83  GLN B OE1 1 
ATOM 3843 N NE2 . GLN B 1 83  ? 34.716  74.608 33.225  1.00 0.62 ? 83  GLN B NE2 1 
ATOM 3844 N N   . ILE B 1 84  ? 33.195  79.291 31.646  1.00 0.60 ? 84  ILE B N   1 
ATOM 3845 C CA  . ILE B 1 84  ? 32.779  80.471 32.403  1.00 0.60 ? 84  ILE B CA  1 
ATOM 3846 C C   . ILE B 1 84  ? 32.354  80.091 33.820  1.00 0.60 ? 84  ILE B C   1 
ATOM 3847 O O   . ILE B 1 84  ? 31.813  80.907 34.571  1.00 0.60 ? 84  ILE B O   1 
ATOM 3848 C CB  . ILE B 1 84  ? 31.703  81.323 31.707  1.00 0.60 ? 84  ILE B CB  1 
ATOM 3849 C CG1 . ILE B 1 84  ? 30.308  80.657 31.633  1.00 0.60 ? 84  ILE B CG1 1 
ATOM 3850 C CG2 . ILE B 1 84  ? 32.245  81.721 30.316  1.00 0.60 ? 84  ILE B CG2 1 
ATOM 3851 C CD1 . ILE B 1 84  ? 29.230  81.522 30.960  1.00 0.60 ? 84  ILE B CD1 1 
ATOM 3852 N N   . GLY B 1 85  ? 32.611  78.826 34.231  1.00 0.64 ? 85  GLY B N   1 
ATOM 3853 C CA  . GLY B 1 85  ? 32.485  78.363 35.607  1.00 0.64 ? 85  GLY B CA  1 
ATOM 3854 C C   . GLY B 1 85  ? 33.761  78.542 36.382  1.00 0.64 ? 85  GLY B C   1 
ATOM 3855 O O   . GLY B 1 85  ? 34.851  78.309 35.874  1.00 0.64 ? 85  GLY B O   1 
ATOM 3856 N N   . TYR B 1 86  ? 33.651  78.932 37.661  1.00 0.61 ? 86  TYR B N   1 
ATOM 3857 C CA  . TYR B 1 86  ? 34.783  79.277 38.495  1.00 0.61 ? 86  TYR B CA  1 
ATOM 3858 C C   . TYR B 1 86  ? 34.586  78.706 39.884  1.00 0.61 ? 86  TYR B C   1 
ATOM 3859 O O   . TYR B 1 86  ? 33.464  78.468 40.328  1.00 0.61 ? 86  TYR B O   1 
ATOM 3860 C CB  . TYR B 1 86  ? 34.906  80.812 38.678  1.00 0.61 ? 86  TYR B CB  1 
ATOM 3861 C CG  . TYR B 1 86  ? 35.369  81.481 37.418  1.00 0.61 ? 86  TYR B CG  1 
ATOM 3862 C CD1 . TYR B 1 86  ? 34.460  81.791 36.398  1.00 0.61 ? 86  TYR B CD1 1 
ATOM 3863 C CD2 . TYR B 1 86  ? 36.716  81.828 37.248  1.00 0.61 ? 86  TYR B CD2 1 
ATOM 3864 C CE1 . TYR B 1 86  ? 34.891  82.423 35.228  1.00 0.61 ? 86  TYR B CE1 1 
ATOM 3865 C CE2 . TYR B 1 86  ? 37.139  82.515 36.099  1.00 0.61 ? 86  TYR B CE2 1 
ATOM 3866 C CZ  . TYR B 1 86  ? 36.221  82.809 35.082  1.00 0.61 ? 86  TYR B CZ  1 
ATOM 3867 O OH  . TYR B 1 86  ? 36.562  83.510 33.907  1.00 0.61 ? 86  TYR B OH  1 
ATOM 3868 N N   . TYR B 1 87  ? 35.696  78.473 40.616  1.00 0.64 ? 87  TYR B N   1 
ATOM 3869 C CA  . TYR B 1 87  ? 35.667  78.053 42.006  1.00 0.64 ? 87  TYR B CA  1 
ATOM 3870 C C   . TYR B 1 87  ? 35.028  79.086 42.938  1.00 0.64 ? 87  TYR B C   1 
ATOM 3871 O O   . TYR B 1 87  ? 35.304  80.286 42.861  1.00 0.64 ? 87  TYR B O   1 
ATOM 3872 C CB  . TYR B 1 87  ? 37.082  77.737 42.553  1.00 0.64 ? 87  TYR B CB  1 
ATOM 3873 C CG  . TYR B 1 87  ? 37.780  76.635 41.803  1.00 0.64 ? 87  TYR B CG  1 
ATOM 3874 C CD1 . TYR B 1 87  ? 37.696  75.301 42.237  1.00 0.64 ? 87  TYR B CD1 1 
ATOM 3875 C CD2 . TYR B 1 87  ? 38.646  76.947 40.741  1.00 0.64 ? 87  TYR B CD2 1 
ATOM 3876 C CE1 . TYR B 1 87  ? 38.480  74.305 41.633  1.00 0.64 ? 87  TYR B CE1 1 
ATOM 3877 C CE2 . TYR B 1 87  ? 39.418  75.954 40.130  1.00 0.64 ? 87  TYR B CE2 1 
ATOM 3878 C CZ  . TYR B 1 87  ? 39.337  74.639 40.581  1.00 0.64 ? 87  TYR B CZ  1 
ATOM 3879 O OH  . TYR B 1 87  ? 40.152  73.663 39.996  1.00 0.64 ? 87  TYR B OH  1 
ATOM 3880 N N   . ARG B 1 88  ? 34.171  78.613 43.862  1.00 0.61 ? 88  ARG B N   1 
ATOM 3881 C CA  . ARG B 1 88  ? 33.499  79.411 44.866  1.00 0.61 ? 88  ARG B CA  1 
ATOM 3882 C C   . ARG B 1 88  ? 33.811  78.844 46.236  1.00 0.61 ? 88  ARG B C   1 
ATOM 3883 O O   . ARG B 1 88  ? 33.516  77.687 46.524  1.00 0.61 ? 88  ARG B O   1 
ATOM 3884 C CB  . ARG B 1 88  ? 31.956  79.348 44.646  1.00 0.61 ? 88  ARG B CB  1 
ATOM 3885 C CG  . ARG B 1 88  ? 31.063  79.885 45.794  1.00 0.61 ? 88  ARG B CG  1 
ATOM 3886 C CD  . ARG B 1 88  ? 29.546  79.706 45.575  1.00 0.61 ? 88  ARG B CD  1 
ATOM 3887 N NE  . ARG B 1 88  ? 29.015  80.915 44.867  1.00 0.61 ? 88  ARG B NE  1 
ATOM 3888 C CZ  . ARG B 1 88  ? 27.774  81.000 44.363  1.00 0.61 ? 88  ARG B CZ  1 
ATOM 3889 N NH1 . ARG B 1 88  ? 27.278  82.186 44.024  1.00 0.61 ? 88  ARG B NH1 1 
ATOM 3890 N NH2 . ARG B 1 88  ? 27.007  79.935 44.178  1.00 0.61 ? 88  ARG B NH2 1 
ATOM 3891 N N   . ARG B 1 89  ? 34.385  79.661 47.140  1.00 0.57 ? 89  ARG B N   1 
ATOM 3892 C CA  . ARG B 1 89  ? 34.483  79.330 48.555  1.00 0.57 ? 89  ARG B CA  1 
ATOM 3893 C C   . ARG B 1 89  ? 33.128  79.557 49.202  1.00 0.57 ? 89  ARG B C   1 
ATOM 3894 O O   . ARG B 1 89  ? 32.613  80.672 49.156  1.00 0.57 ? 89  ARG B O   1 
ATOM 3895 C CB  . ARG B 1 89  ? 35.532  80.232 49.250  1.00 0.57 ? 89  ARG B CB  1 
ATOM 3896 C CG  . ARG B 1 89  ? 35.790  79.925 50.743  1.00 0.57 ? 89  ARG B CG  1 
ATOM 3897 C CD  . ARG B 1 89  ? 36.965  80.743 51.296  1.00 0.57 ? 89  ARG B CD  1 
ATOM 3898 N NE  . ARG B 1 89  ? 37.151  80.382 52.740  1.00 0.57 ? 89  ARG B NE  1 
ATOM 3899 C CZ  . ARG B 1 89  ? 38.200  80.775 53.481  1.00 0.57 ? 89  ARG B CZ  1 
ATOM 3900 N NH1 . ARG B 1 89  ? 38.268  80.438 54.766  1.00 0.57 ? 89  ARG B NH1 1 
ATOM 3901 N NH2 . ARG B 1 89  ? 39.184  81.495 52.954  1.00 0.57 ? 89  ARG B NH2 1 
ATOM 3902 N N   . ALA B 1 90  ? 32.506  78.519 49.793  1.00 0.54 ? 90  ALA B N   1 
ATOM 3903 C CA  . ALA B 1 90  ? 31.127  78.586 50.232  1.00 0.54 ? 90  ALA B CA  1 
ATOM 3904 C C   . ALA B 1 90  ? 31.017  78.766 51.745  1.00 0.54 ? 90  ALA B C   1 
ATOM 3905 O O   . ALA B 1 90  ? 31.672  78.077 52.527  1.00 0.54 ? 90  ALA B O   1 
ATOM 3906 C CB  . ALA B 1 90  ? 30.413  77.283 49.800  1.00 0.54 ? 90  ALA B CB  1 
ATOM 3907 N N   . THR B 1 91  ? 30.142  79.679 52.222  1.00 0.39 ? 91  THR B N   1 
ATOM 3908 C CA  . THR B 1 91  ? 29.993  79.985 53.649  1.00 0.39 ? 91  THR B CA  1 
ATOM 3909 C C   . THR B 1 91  ? 28.974  79.082 54.304  1.00 0.39 ? 91  THR B C   1 
ATOM 3910 O O   . THR B 1 91  ? 28.693  79.165 55.499  1.00 0.39 ? 91  THR B O   1 
ATOM 3911 C CB  . THR B 1 91  ? 29.552  81.423 53.952  1.00 0.39 ? 91  THR B CB  1 
ATOM 3912 O OG1 . THR B 1 91  ? 28.269  81.756 53.434  1.00 0.39 ? 91  THR B OG1 1 
ATOM 3913 C CG2 . THR B 1 91  ? 30.571  82.402 53.355  1.00 0.39 ? 91  THR B CG2 1 
ATOM 3914 N N   . ARG B 1 92  ? 28.388  78.157 53.523  1.00 0.32 ? 92  ARG B N   1 
ATOM 3915 C CA  . ARG B 1 92  ? 27.262  77.354 53.940  1.00 0.32 ? 92  ARG B CA  1 
ATOM 3916 C C   . ARG B 1 92  ? 27.478  76.382 55.091  1.00 0.32 ? 92  ARG B C   1 
ATOM 3917 O O   . ARG B 1 92  ? 26.598  76.270 55.952  1.00 0.32 ? 92  ARG B O   1 
ATOM 3918 C CB  . ARG B 1 92  ? 26.715  76.548 52.737  1.00 0.32 ? 92  ARG B CB  1 
ATOM 3919 C CG  . ARG B 1 92  ? 25.463  75.665 52.980  1.00 0.32 ? 92  ARG B CG  1 
ATOM 3920 C CD  . ARG B 1 92  ? 24.158  76.421 53.292  1.00 0.32 ? 92  ARG B CD  1 
ATOM 3921 N NE  . ARG B 1 92  ? 24.155  76.784 54.745  1.00 0.32 ? 92  ARG B NE  1 
ATOM 3922 C CZ  . ARG B 1 92  ? 23.212  77.528 55.341  1.00 0.32 ? 92  ARG B CZ  1 
ATOM 3923 N NH1 . ARG B 1 92  ? 23.347  77.839 56.628  1.00 0.32 ? 92  ARG B NH1 1 
ATOM 3924 N NH2 . ARG B 1 92  ? 22.157  77.970 54.668  1.00 0.32 ? 92  ARG B NH2 1 
ATOM 3925 N N   . ARG B 1 93  ? 28.589  75.613 55.111  1.00 0.41 ? 93  ARG B N   1 
ATOM 3926 C CA  . ARG B 1 93  ? 28.803  74.632 56.157  1.00 0.41 ? 93  ARG B CA  1 
ATOM 3927 C C   . ARG B 1 93  ? 30.225  74.095 56.233  1.00 0.41 ? 93  ARG B C   1 
ATOM 3928 O O   . ARG B 1 93  ? 30.933  74.008 55.229  1.00 0.41 ? 93  ARG B O   1 
ATOM 3929 C CB  . ARG B 1 93  ? 27.870  73.390 56.004  1.00 0.41 ? 93  ARG B CB  1 
ATOM 3930 C CG  . ARG B 1 93  ? 28.061  72.579 54.701  1.00 0.41 ? 93  ARG B CG  1 
ATOM 3931 C CD  . ARG B 1 93  ? 27.218  71.299 54.610  1.00 0.41 ? 93  ARG B CD  1 
ATOM 3932 N NE  . ARG B 1 93  ? 25.774  71.671 54.395  1.00 0.41 ? 93  ARG B NE  1 
ATOM 3933 C CZ  . ARG B 1 93  ? 24.801  71.611 55.319  1.00 0.41 ? 93  ARG B CZ  1 
ATOM 3934 N NH1 . ARG B 1 93  ? 23.553  71.932 54.974  1.00 0.41 ? 93  ARG B NH1 1 
ATOM 3935 N NH2 . ARG B 1 93  ? 25.037  71.239 56.571  1.00 0.41 ? 93  ARG B NH2 1 
ATOM 3936 N N   . ILE B 1 94  ? 30.612  73.625 57.440  1.00 0.42 ? 94  ILE B N   1 
ATOM 3937 C CA  . ILE B 1 94  ? 31.723  72.713 57.680  1.00 0.42 ? 94  ILE B CA  1 
ATOM 3938 C C   . ILE B 1 94  ? 31.065  71.373 57.978  1.00 0.42 ? 94  ILE B C   1 
ATOM 3939 O O   . ILE B 1 94  ? 30.042  71.319 58.662  1.00 0.42 ? 94  ILE B O   1 
ATOM 3940 C CB  . ILE B 1 94  ? 32.611  73.148 58.855  1.00 0.42 ? 94  ILE B CB  1 
ATOM 3941 C CG1 . ILE B 1 94  ? 33.290  74.503 58.544  1.00 0.42 ? 94  ILE B CG1 1 
ATOM 3942 C CG2 . ILE B 1 94  ? 33.686  72.076 59.163  1.00 0.42 ? 94  ILE B CG2 1 
ATOM 3943 C CD1 . ILE B 1 94  ? 33.938  75.183 59.759  1.00 0.42 ? 94  ILE B CD1 1 
ATOM 3944 N N   . ARG B 1 95  ? 31.574  70.252 57.420  1.00 0.39 ? 95  ARG B N   1 
ATOM 3945 C CA  . ARG B 1 95  ? 31.037  68.926 57.681  1.00 0.39 ? 95  ARG B CA  1 
ATOM 3946 C C   . ARG B 1 95  ? 32.175  67.980 58.032  1.00 0.39 ? 95  ARG B C   1 
ATOM 3947 O O   . ARG B 1 95  ? 33.237  68.028 57.416  1.00 0.39 ? 95  ARG B O   1 
ATOM 3948 C CB  . ARG B 1 95  ? 30.247  68.385 56.458  1.00 0.39 ? 95  ARG B CB  1 
ATOM 3949 C CG  . ARG B 1 95  ? 29.540  67.025 56.667  1.00 0.39 ? 95  ARG B CG  1 
ATOM 3950 C CD  . ARG B 1 95  ? 28.636  66.627 55.495  1.00 0.39 ? 95  ARG B CD  1 
ATOM 3951 N NE  . ARG B 1 95  ? 28.042  65.283 55.805  1.00 0.39 ? 95  ARG B NE  1 
ATOM 3952 C CZ  . ARG B 1 95  ? 27.185  64.627 55.010  1.00 0.39 ? 95  ARG B CZ  1 
ATOM 3953 N NH1 . ARG B 1 95  ? 26.720  63.432 55.371  1.00 0.39 ? 95  ARG B NH1 1 
ATOM 3954 N NH2 . ARG B 1 95  ? 26.762  65.157 53.868  1.00 0.39 ? 95  ARG B NH2 1 
ATOM 3955 N N   . GLY B 1 96  ? 31.963  67.087 59.028  1.00 0.45 ? 96  GLY B N   1 
ATOM 3956 C CA  . GLY B 1 96  ? 33.020  66.264 59.618  1.00 0.45 ? 96  GLY B CA  1 
ATOM 3957 C C   . GLY B 1 96  ? 33.995  67.039 60.471  1.00 0.45 ? 96  GLY B C   1 
ATOM 3958 O O   . GLY B 1 96  ? 33.770  68.203 60.784  1.00 0.45 ? 96  GLY B O   1 
ATOM 3959 N N   . GLY B 1 97  ? 35.085  66.385 60.919  1.00 0.44 ? 97  GLY B N   1 
ATOM 3960 C CA  . GLY B 1 97  ? 36.110  67.027 61.737  1.00 0.44 ? 97  GLY B CA  1 
ATOM 3961 C C   . GLY B 1 97  ? 37.497  66.540 61.423  1.00 0.44 ? 97  GLY B C   1 
ATOM 3962 O O   . GLY B 1 97  ? 37.674  65.425 60.945  1.00 0.44 ? 97  GLY B O   1 
ATOM 3963 N N   . ASP B 1 98  ? 38.525  67.366 61.697  1.00 0.39 ? 98  ASP B N   1 
ATOM 3964 C CA  . ASP B 1 98  ? 39.905  67.007 61.486  1.00 0.39 ? 98  ASP B CA  1 
ATOM 3965 C C   . ASP B 1 98  ? 40.720  67.768 62.522  1.00 0.39 ? 98  ASP B C   1 
ATOM 3966 O O   . ASP B 1 98  ? 40.306  68.843 62.957  1.00 0.39 ? 98  ASP B O   1 
ATOM 3967 C CB  . ASP B 1 98  ? 40.351  67.367 60.045  1.00 0.39 ? 98  ASP B CB  1 
ATOM 3968 C CG  . ASP B 1 98  ? 41.731  66.802 59.752  1.00 0.39 ? 98  ASP B CG  1 
ATOM 3969 O OD1 . ASP B 1 98  ? 42.094  65.770 60.386  1.00 0.39 ? 98  ASP B OD1 1 
ATOM 3970 O OD2 . ASP B 1 98  ? 42.436  67.350 58.879  1.00 0.39 ? 98  ASP B OD2 1 
ATOM 3971 N N   . GLY B 1 99  ? 41.880  67.209 62.946  1.00 0.41 ? 99  GLY B N   1 
ATOM 3972 C CA  . GLY B 1 99  ? 42.818  67.803 63.903  1.00 0.41 ? 99  GLY B CA  1 
ATOM 3973 C C   . GLY B 1 99  ? 42.232  68.467 65.128  1.00 0.41 ? 99  GLY B C   1 
ATOM 3974 O O   . GLY B 1 99  ? 41.366  67.948 65.829  1.00 0.41 ? 99  GLY B O   1 
ATOM 3975 N N   . LYS B 1 100 ? 42.718  69.682 65.446  1.00 0.35 ? 100 LYS B N   1 
ATOM 3976 C CA  . LYS B 1 100 ? 41.946  70.596 66.264  1.00 0.35 ? 100 LYS B CA  1 
ATOM 3977 C C   . LYS B 1 100 ? 40.776  71.135 65.455  1.00 0.35 ? 100 LYS B C   1 
ATOM 3978 O O   . LYS B 1 100 ? 40.973  71.661 64.366  1.00 0.35 ? 100 LYS B O   1 
ATOM 3979 C CB  . LYS B 1 100 ? 42.809  71.784 66.747  1.00 0.35 ? 100 LYS B CB  1 
ATOM 3980 C CG  . LYS B 1 100 ? 43.927  71.358 67.710  1.00 0.35 ? 100 LYS B CG  1 
ATOM 3981 C CD  . LYS B 1 100 ? 44.757  72.561 68.187  1.00 0.35 ? 100 LYS B CD  1 
ATOM 3982 C CE  . LYS B 1 100 ? 45.834  72.222 69.224  1.00 0.35 ? 100 LYS B CE  1 
ATOM 3983 N NZ  . LYS B 1 100 ? 46.908  71.417 68.602  1.00 0.35 ? 100 LYS B NZ  1 
ATOM 3984 N N   . MET B 1 101 ? 39.535  71.040 65.981  1.00 0.30 ? 101 MET B N   1 
ATOM 3985 C CA  . MET B 1 101 ? 38.299  71.123 65.206  1.00 0.30 ? 101 MET B CA  1 
ATOM 3986 C C   . MET B 1 101 ? 38.105  72.374 64.351  1.00 0.30 ? 101 MET B C   1 
ATOM 3987 O O   . MET B 1 101 ? 37.515  72.338 63.276  1.00 0.30 ? 101 MET B O   1 
ATOM 3988 C CB  . MET B 1 101 ? 37.092  70.939 66.166  1.00 0.30 ? 101 MET B CB  1 
ATOM 3989 C CG  . MET B 1 101 ? 35.725  70.729 65.484  1.00 0.30 ? 101 MET B CG  1 
ATOM 3990 S SD  . MET B 1 101 ? 35.646  69.205 64.502  1.00 0.30 ? 101 MET B SD  1 
ATOM 3991 C CE  . MET B 1 101 ? 33.911  69.402 64.012  1.00 0.30 ? 101 MET B CE  1 
ATOM 3992 N N   . LYS B 1 102 ? 38.637  73.516 64.815  1.00 0.42 ? 102 LYS B N   1 
ATOM 3993 C CA  . LYS B 1 102 ? 38.603  74.791 64.131  1.00 0.42 ? 102 LYS B CA  1 
ATOM 3994 C C   . LYS B 1 102 ? 39.419  74.857 62.830  1.00 0.42 ? 102 LYS B C   1 
ATOM 3995 O O   . LYS B 1 102 ? 39.172  75.721 61.992  1.00 0.42 ? 102 LYS B O   1 
ATOM 3996 C CB  . LYS B 1 102 ? 39.119  75.860 65.130  1.00 0.42 ? 102 LYS B CB  1 
ATOM 3997 C CG  . LYS B 1 102 ? 38.893  77.315 64.686  1.00 0.42 ? 102 LYS B CG  1 
ATOM 3998 C CD  . LYS B 1 102 ? 39.286  78.336 65.766  1.00 0.42 ? 102 LYS B CD  1 
ATOM 3999 C CE  . LYS B 1 102 ? 39.046  79.781 65.313  1.00 0.42 ? 102 LYS B CE  1 
ATOM 4000 N NZ  . LYS B 1 102 ? 39.426  80.735 66.381  1.00 0.42 ? 102 LYS B NZ  1 
ATOM 4001 N N   . ASP B 1 103 ? 40.412  73.956 62.635  1.00 0.34 ? 103 ASP B N   1 
ATOM 4002 C CA  . ASP B 1 103 ? 41.320  73.960 61.501  1.00 0.34 ? 103 ASP B CA  1 
ATOM 4003 C C   . ASP B 1 103 ? 40.671  73.382 60.236  1.00 0.34 ? 103 ASP B C   1 
ATOM 4004 O O   . ASP B 1 103 ? 41.067  73.658 59.104  1.00 0.34 ? 103 ASP B O   1 
ATOM 4005 C CB  . ASP B 1 103 ? 42.578  73.166 61.951  1.00 0.34 ? 103 ASP B CB  1 
ATOM 4006 C CG  . ASP B 1 103 ? 43.832  73.498 61.155  1.00 0.34 ? 103 ASP B CG  1 
ATOM 4007 O OD1 . ASP B 1 103 ? 43.989  74.683 60.759  1.00 0.34 ? 103 ASP B OD1 1 
ATOM 4008 O OD2 . ASP B 1 103 ? 44.694  72.589 61.043  1.00 0.34 ? 103 ASP B OD2 1 
ATOM 4009 N N   . LEU B 1 104 ? 39.581  72.595 60.380  1.00 0.46 ? 104 LEU B N   1 
ATOM 4010 C CA  . LEU B 1 104 ? 38.878  72.085 59.218  1.00 0.46 ? 104 LEU B CA  1 
ATOM 4011 C C   . LEU B 1 104 ? 38.056  73.157 58.511  1.00 0.46 ? 104 LEU B C   1 
ATOM 4012 O O   . LEU B 1 104 ? 37.066  73.686 59.016  1.00 0.46 ? 104 LEU B O   1 
ATOM 4013 C CB  . LEU B 1 104 ? 37.999  70.854 59.536  1.00 0.46 ? 104 LEU B CB  1 
ATOM 4014 C CG  . LEU B 1 104 ? 37.315  70.201 58.307  1.00 0.46 ? 104 LEU B CG  1 
ATOM 4015 C CD1 . LEU B 1 104 ? 38.313  69.732 57.232  1.00 0.46 ? 104 LEU B CD1 1 
ATOM 4016 C CD2 . LEU B 1 104 ? 36.445  69.023 58.754  1.00 0.46 ? 104 LEU B CD2 1 
ATOM 4017 N N   . SER B 1 105 ? 38.481  73.505 57.282  1.00 0.55 ? 105 SER B N   1 
ATOM 4018 C CA  . SER B 1 105 ? 37.862  74.484 56.407  1.00 0.55 ? 105 SER B CA  1 
ATOM 4019 C C   . SER B 1 105 ? 36.428  74.184 55.969  1.00 0.55 ? 105 SER B C   1 
ATOM 4020 O O   . SER B 1 105 ? 36.069  73.012 55.842  1.00 0.55 ? 105 SER B O   1 
ATOM 4021 C CB  . SER B 1 105 ? 38.687  74.695 55.110  1.00 0.55 ? 105 SER B CB  1 
ATOM 4022 O OG  . SER B 1 105 ? 40.090  74.619 55.353  1.00 0.55 ? 105 SER B OG  1 
ATOM 4023 N N   . PRO B 1 106 ? 35.558  75.165 55.692  1.00 0.55 ? 106 PRO B N   1 
ATOM 4024 C CA  . PRO B 1 106 ? 34.286  74.916 55.015  1.00 0.55 ? 106 PRO B CA  1 
ATOM 4025 C C   . PRO B 1 106 ? 34.439  74.391 53.596  1.00 0.55 ? 106 PRO B C   1 
ATOM 4026 O O   . PRO B 1 106 ? 35.551  74.266 53.088  1.00 0.55 ? 106 PRO B O   1 
ATOM 4027 C CB  . PRO B 1 106 ? 33.585  76.281 55.049  1.00 0.55 ? 106 PRO B CB  1 
ATOM 4028 C CG  . PRO B 1 106 ? 34.735  77.282 54.988  1.00 0.55 ? 106 PRO B CG  1 
ATOM 4029 C CD  . PRO B 1 106 ? 35.817  76.602 55.830  1.00 0.55 ? 106 PRO B CD  1 
ATOM 4030 N N   . ARG B 1 107 ? 33.308  74.050 52.954  1.00 0.55 ? 107 ARG B N   1 
ATOM 4031 C CA  . ARG B 1 107 ? 33.253  73.578 51.584  1.00 0.55 ? 107 ARG B CA  1 
ATOM 4032 C C   . ARG B 1 107 ? 33.546  74.612 50.497  1.00 0.55 ? 107 ARG B C   1 
ATOM 4033 O O   . ARG B 1 107 ? 33.321  75.814 50.632  1.00 0.55 ? 107 ARG B O   1 
ATOM 4034 C CB  . ARG B 1 107 ? 31.874  72.960 51.266  1.00 0.55 ? 107 ARG B CB  1 
ATOM 4035 C CG  . ARG B 1 107 ? 31.650  71.572 51.891  1.00 0.55 ? 107 ARG B CG  1 
ATOM 4036 C CD  . ARG B 1 107 ? 30.309  71.008 51.435  1.00 0.55 ? 107 ARG B CD  1 
ATOM 4037 N NE  . ARG B 1 107 ? 30.198  69.577 51.846  1.00 0.55 ? 107 ARG B NE  1 
ATOM 4038 C CZ  . ARG B 1 107 ? 29.272  68.758 51.327  1.00 0.55 ? 107 ARG B CZ  1 
ATOM 4039 N NH1 . ARG B 1 107 ? 29.334  67.452 51.588  1.00 0.55 ? 107 ARG B NH1 1 
ATOM 4040 N NH2 . ARG B 1 107 ? 28.316  69.207 50.518  1.00 0.55 ? 107 ARG B NH2 1 
ATOM 4041 N N   . TRP B 1 108 ? 34.029  74.119 49.346  1.00 0.52 ? 108 TRP B N   1 
ATOM 4042 C CA  . TRP B 1 108 ? 34.158  74.845 48.104  1.00 0.52 ? 108 TRP B CA  1 
ATOM 4043 C C   . TRP B 1 108 ? 33.290  74.173 47.049  1.00 0.52 ? 108 TRP B C   1 
ATOM 4044 O O   . TRP B 1 108 ? 33.128  72.952 47.026  1.00 0.52 ? 108 TRP B O   1 
ATOM 4045 C CB  . TRP B 1 108 ? 35.620  74.830 47.591  1.00 0.52 ? 108 TRP B CB  1 
ATOM 4046 C CG  . TRP B 1 108 ? 36.536  75.964 48.003  1.00 0.52 ? 108 TRP B CG  1 
ATOM 4047 C CD1 . TRP B 1 108 ? 37.099  76.870 47.154  1.00 0.52 ? 108 TRP B CD1 1 
ATOM 4048 C CD2 . TRP B 1 108 ? 37.068  76.259 49.310  1.00 0.52 ? 108 TRP B CD2 1 
ATOM 4049 N NE1 . TRP B 1 108 ? 37.948  77.706 47.836  1.00 0.52 ? 108 TRP B NE1 1 
ATOM 4050 C CE2 . TRP B 1 108 ? 37.934  77.360 49.158  1.00 0.52 ? 108 TRP B CE2 1 
ATOM 4051 C CE3 . TRP B 1 108 ? 36.877  75.678 50.558  1.00 0.52 ? 108 TRP B CE3 1 
ATOM 4052 C CZ2 . TRP B 1 108 ? 38.602  77.899 50.242  1.00 0.52 ? 108 TRP B CZ2 1 
ATOM 4053 C CZ3 . TRP B 1 108 ? 37.505  76.266 51.667  1.00 0.52 ? 108 TRP B CZ3 1 
ATOM 4054 C CH2 . TRP B 1 108 ? 38.354  77.365 51.516  1.00 0.52 ? 108 TRP B CH2 1 
ATOM 4055 N N   . TYR B 1 109 ? 32.722  74.982 46.136  1.00 0.62 ? 109 TYR B N   1 
ATOM 4056 C CA  . TYR B 1 109 ? 31.814  74.566 45.078  1.00 0.62 ? 109 TYR B CA  1 
ATOM 4057 C C   . TYR B 1 109 ? 32.185  75.318 43.799  1.00 0.62 ? 109 TYR B C   1 
ATOM 4058 O O   . TYR B 1 109 ? 33.165  76.058 43.769  1.00 0.62 ? 109 TYR B O   1 
ATOM 4059 C CB  . TYR B 1 109 ? 30.329  74.891 45.418  1.00 0.62 ? 109 TYR B CB  1 
ATOM 4060 C CG  . TYR B 1 109 ? 29.777  74.145 46.605  1.00 0.62 ? 109 TYR B CG  1 
ATOM 4061 C CD1 . TYR B 1 109 ? 29.945  72.759 46.766  1.00 0.62 ? 109 TYR B CD1 1 
ATOM 4062 C CD2 . TYR B 1 109 ? 28.970  74.833 47.527  1.00 0.62 ? 109 TYR B CD2 1 
ATOM 4063 C CE1 . TYR B 1 109 ? 29.336  72.082 47.836  1.00 0.62 ? 109 TYR B CE1 1 
ATOM 4064 C CE2 . TYR B 1 109 ? 28.359  74.160 48.592  1.00 0.62 ? 109 TYR B CE2 1 
ATOM 4065 C CZ  . TYR B 1 109 ? 28.544  72.784 48.748  1.00 0.62 ? 109 TYR B CZ  1 
ATOM 4066 O OH  . TYR B 1 109 ? 27.884  72.128 49.809  1.00 0.62 ? 109 TYR B OH  1 
ATOM 4067 N N   . PHE B 1 110 ? 31.414  75.152 42.700  1.00 0.62 ? 110 PHE B N   1 
ATOM 4068 C CA  . PHE B 1 110 ? 31.617  75.870 41.445  1.00 0.62 ? 110 PHE B CA  1 
ATOM 4069 C C   . PHE B 1 110 ? 30.416  76.767 41.151  1.00 0.62 ? 110 PHE B C   1 
ATOM 4070 O O   . PHE B 1 110 ? 29.286  76.450 41.513  1.00 0.62 ? 110 PHE B O   1 
ATOM 4071 C CB  . PHE B 1 110 ? 31.831  74.918 40.236  1.00 0.62 ? 110 PHE B CB  1 
ATOM 4072 C CG  . PHE B 1 110 ? 33.171  74.242 40.306  1.00 0.62 ? 110 PHE B CG  1 
ATOM 4073 C CD1 . PHE B 1 110 ? 34.295  74.846 39.720  1.00 0.62 ? 110 PHE B CD1 1 
ATOM 4074 C CD2 . PHE B 1 110 ? 33.322  72.992 40.927  1.00 0.62 ? 110 PHE B CD2 1 
ATOM 4075 C CE1 . PHE B 1 110 ? 35.539  74.205 39.733  1.00 0.62 ? 110 PHE B CE1 1 
ATOM 4076 C CE2 . PHE B 1 110 ? 34.565  72.349 40.947  1.00 0.62 ? 110 PHE B CE2 1 
ATOM 4077 C CZ  . PHE B 1 110 ? 35.673  72.951 40.341  1.00 0.62 ? 110 PHE B CZ  1 
ATOM 4078 N N   . TYR B 1 111 ? 30.654  77.928 40.503  1.00 0.58 ? 111 TYR B N   1 
ATOM 4079 C CA  . TYR B 1 111 ? 29.641  78.913 40.154  1.00 0.58 ? 111 TYR B CA  1 
ATOM 4080 C C   . TYR B 1 111 ? 29.925  79.426 38.743  1.00 0.58 ? 111 TYR B C   1 
ATOM 4081 O O   . TYR B 1 111 ? 31.077  79.648 38.380  1.00 0.58 ? 111 TYR B O   1 
ATOM 4082 C CB  . TYR B 1 111 ? 29.658  80.073 41.198  1.00 0.58 ? 111 TYR B CB  1 
ATOM 4083 C CG  . TYR B 1 111 ? 28.923  81.329 40.781  1.00 0.58 ? 111 TYR B CG  1 
ATOM 4084 C CD1 . TYR B 1 111 ? 27.529  81.454 40.891  1.00 0.58 ? 111 TYR B CD1 1 
ATOM 4085 C CD2 . TYR B 1 111 ? 29.653  82.393 40.229  1.00 0.58 ? 111 TYR B CD2 1 
ATOM 4086 C CE1 . TYR B 1 111 ? 26.883  82.625 40.460  1.00 0.58 ? 111 TYR B CE1 1 
ATOM 4087 C CE2 . TYR B 1 111 ? 29.010  83.553 39.793  1.00 0.58 ? 111 TYR B CE2 1 
ATOM 4088 C CZ  . TYR B 1 111 ? 27.628  83.659 39.881  1.00 0.58 ? 111 TYR B CZ  1 
ATOM 4089 O OH  . TYR B 1 111 ? 27.026  84.813 39.357  1.00 0.58 ? 111 TYR B OH  1 
ATOM 4090 N N   . TYR B 1 112 ? 28.872  79.627 37.920  1.00 0.60 ? 112 TYR B N   1 
ATOM 4091 C CA  . TYR B 1 112 ? 28.960  80.095 36.545  1.00 0.60 ? 112 TYR B CA  1 
ATOM 4092 C C   . TYR B 1 112 ? 28.552  81.554 36.504  1.00 0.60 ? 112 TYR B C   1 
ATOM 4093 O O   . TYR B 1 112 ? 27.495  81.927 37.001  1.00 0.60 ? 112 TYR B O   1 
ATOM 4094 C CB  . TYR B 1 112 ? 28.056  79.260 35.591  1.00 0.60 ? 112 TYR B CB  1 
ATOM 4095 C CG  . TYR B 1 112 ? 28.764  77.998 35.171  1.00 0.60 ? 112 TYR B CG  1 
ATOM 4096 C CD1 . TYR B 1 112 ? 29.065  76.976 36.088  1.00 0.60 ? 112 TYR B CD1 1 
ATOM 4097 C CD2 . TYR B 1 112 ? 29.192  77.854 33.843  1.00 0.60 ? 112 TYR B CD2 1 
ATOM 4098 C CE1 . TYR B 1 112 ? 29.820  75.862 35.696  1.00 0.60 ? 112 TYR B CE1 1 
ATOM 4099 C CE2 . TYR B 1 112 ? 29.954  76.747 33.448  1.00 0.60 ? 112 TYR B CE2 1 
ATOM 4100 C CZ  . TYR B 1 112 ? 30.268  75.750 34.377  1.00 0.60 ? 112 TYR B CZ  1 
ATOM 4101 O OH  . TYR B 1 112 ? 31.084  74.669 33.996  1.00 0.60 ? 112 TYR B OH  1 
ATOM 4102 N N   . LEU B 1 113 ? 29.416  82.429 35.945  1.00 0.55 ? 113 LEU B N   1 
ATOM 4103 C CA  . LEU B 1 113 ? 29.272  83.874 36.046  1.00 0.55 ? 113 LEU B CA  1 
ATOM 4104 C C   . LEU B 1 113 ? 28.020  84.525 35.462  1.00 0.55 ? 113 LEU B C   1 
ATOM 4105 O O   . LEU B 1 113 ? 27.500  84.160 34.407  1.00 0.55 ? 113 LEU B O   1 
ATOM 4106 C CB  . LEU B 1 113 ? 30.484  84.644 35.466  1.00 0.55 ? 113 LEU B CB  1 
ATOM 4107 C CG  . LEU B 1 113 ? 31.864  84.290 36.054  1.00 0.55 ? 113 LEU B CG  1 
ATOM 4108 C CD1 . LEU B 1 113 ? 32.938  85.195 35.430  1.00 0.55 ? 113 LEU B CD1 1 
ATOM 4109 C CD2 . LEU B 1 113 ? 31.926  84.380 37.588  1.00 0.55 ? 113 LEU B CD2 1 
ATOM 4110 N N   . GLY B 1 114 ? 27.560  85.608 36.125  1.00 0.51 ? 114 GLY B N   1 
ATOM 4111 C CA  . GLY B 1 114 ? 26.432  86.395 35.662  1.00 0.51 ? 114 GLY B CA  1 
ATOM 4112 C C   . GLY B 1 114 ? 25.066  85.976 36.114  1.00 0.51 ? 114 GLY B C   1 
ATOM 4113 O O   . GLY B 1 114 ? 24.087  86.454 35.548  1.00 0.51 ? 114 GLY B O   1 
ATOM 4114 N N   . THR B 1 115 ? 24.933  85.078 37.103  1.00 0.39 ? 115 THR B N   1 
ATOM 4115 C CA  . THR B 1 115 ? 23.644  84.621 37.597  1.00 0.39 ? 115 THR B CA  1 
ATOM 4116 C C   . THR B 1 115 ? 23.369  85.212 38.979  1.00 0.39 ? 115 THR B C   1 
ATOM 4117 O O   . THR B 1 115 ? 24.229  85.284 39.850  1.00 0.39 ? 115 THR B O   1 
ATOM 4118 C CB  . THR B 1 115 ? 23.515  83.092 37.591  1.00 0.39 ? 115 THR B CB  1 
ATOM 4119 O OG1 . THR B 1 115 ? 24.519  82.451 38.353  1.00 0.39 ? 115 THR B OG1 1 
ATOM 4120 C CG2 . THR B 1 115 ? 23.715  82.533 36.173  1.00 0.39 ? 115 THR B CG2 1 
ATOM 4121 N N   . GLY B 1 116 ? 22.155  85.753 39.233  1.00 0.37 ? 116 GLY B N   1 
ATOM 4122 C CA  . GLY B 1 116 ? 21.935  86.394 40.521  1.00 0.37 ? 116 GLY B CA  1 
ATOM 4123 C C   . GLY B 1 116 ? 20.604  87.092 40.571  1.00 0.37 ? 116 GLY B C   1 
ATOM 4124 O O   . GLY B 1 116 ? 19.699  86.697 39.836  1.00 0.37 ? 116 GLY B O   1 
ATOM 4125 N N   . PRO B 1 117 ? 20.416  88.113 41.410  1.00 0.27 ? 117 PRO B N   1 
ATOM 4126 C CA  . PRO B 1 117 ? 19.243  88.992 41.396  1.00 0.27 ? 117 PRO B CA  1 
ATOM 4127 C C   . PRO B 1 117 ? 18.937  89.709 40.082  1.00 0.27 ? 117 PRO B C   1 
ATOM 4128 O O   . PRO B 1 117 ? 19.769  89.715 39.179  1.00 0.27 ? 117 PRO B O   1 
ATOM 4129 C CB  . PRO B 1 117 ? 19.536  90.026 42.502  1.00 0.27 ? 117 PRO B CB  1 
ATOM 4130 C CG  . PRO B 1 117 ? 20.573  89.358 43.407  1.00 0.27 ? 117 PRO B CG  1 
ATOM 4131 C CD  . PRO B 1 117 ? 21.388  88.516 42.429  1.00 0.27 ? 117 PRO B CD  1 
ATOM 4132 N N   . GLU B 1 118 ? 17.771  90.406 40.020  1.00 0.21 ? 118 GLU B N   1 
ATOM 4133 C CA  . GLU B 1 118 ? 17.209  91.143 38.882  1.00 0.21 ? 118 GLU B CA  1 
ATOM 4134 C C   . GLU B 1 118 ? 18.162  92.152 38.232  1.00 0.21 ? 118 GLU B C   1 
ATOM 4135 O O   . GLU B 1 118 ? 18.094  92.458 37.045  1.00 0.21 ? 118 GLU B O   1 
ATOM 4136 C CB  . GLU B 1 118 ? 15.915  91.867 39.361  1.00 0.21 ? 118 GLU B CB  1 
ATOM 4137 C CG  . GLU B 1 118 ? 15.056  92.543 38.251  1.00 0.21 ? 118 GLU B CG  1 
ATOM 4138 C CD  . GLU B 1 118 ? 14.415  91.567 37.259  1.00 0.21 ? 118 GLU B CD  1 
ATOM 4139 O OE1 . GLU B 1 118 ? 14.321  90.355 37.583  1.00 0.21 ? 118 GLU B OE1 1 
ATOM 4140 O OE2 . GLU B 1 118 ? 14.016  92.033 36.155  1.00 0.21 ? 118 GLU B OE2 1 
ATOM 4141 N N   . ALA B 1 119 ? 19.133  92.669 39.010  1.00 0.24 ? 119 ALA B N   1 
ATOM 4142 C CA  . ALA B 1 119 ? 20.187  93.543 38.542  1.00 0.24 ? 119 ALA B CA  1 
ATOM 4143 C C   . ALA B 1 119 ? 21.214  92.873 37.616  1.00 0.24 ? 119 ALA B C   1 
ATOM 4144 O O   . ALA B 1 119 ? 21.998  93.564 36.969  1.00 0.24 ? 119 ALA B O   1 
ATOM 4145 C CB  . ALA B 1 119 ? 20.916  94.130 39.772  1.00 0.24 ? 119 ALA B CB  1 
ATOM 4146 N N   . GLY B 1 120 ? 21.255  91.520 37.528  1.00 0.33 ? 120 GLY B N   1 
ATOM 4147 C CA  . GLY B 1 120 ? 22.117  90.815 36.576  1.00 0.33 ? 120 GLY B CA  1 
ATOM 4148 C C   . GLY B 1 120 ? 23.580  90.794 36.932  1.00 0.33 ? 120 GLY B C   1 
ATOM 4149 O O   . GLY B 1 120 ? 24.458  90.914 36.079  1.00 0.33 ? 120 GLY B O   1 
ATOM 4150 N N   . LEU B 1 121 ? 23.866  90.660 38.237  1.00 0.29 ? 121 LEU B N   1 
ATOM 4151 C CA  . LEU B 1 121 ? 25.190  90.761 38.817  1.00 0.29 ? 121 LEU B CA  1 
ATOM 4152 C C   . LEU B 1 121 ? 26.205  89.725 38.315  1.00 0.29 ? 121 LEU B C   1 
ATOM 4153 O O   . LEU B 1 121 ? 25.831  88.593 38.014  1.00 0.29 ? 121 LEU B O   1 
ATOM 4154 C CB  . LEU B 1 121 ? 25.112  90.705 40.364  1.00 0.29 ? 121 LEU B CB  1 
ATOM 4155 C CG  . LEU B 1 121 ? 24.225  91.781 41.029  1.00 0.29 ? 121 LEU B CG  1 
ATOM 4156 C CD1 . LEU B 1 121 ? 24.206  91.571 42.552  1.00 0.29 ? 121 LEU B CD1 1 
ATOM 4157 C CD2 . LEU B 1 121 ? 24.673  93.216 40.704  1.00 0.29 ? 121 LEU B CD2 1 
ATOM 4158 N N   . PRO B 1 122 ? 27.507  90.020 38.197  1.00 0.51 ? 122 PRO B N   1 
ATOM 4159 C CA  . PRO B 1 122 ? 28.499  89.048 37.746  1.00 0.51 ? 122 PRO B CA  1 
ATOM 4160 C C   . PRO B 1 122 ? 28.676  87.908 38.743  1.00 0.51 ? 122 PRO B C   1 
ATOM 4161 O O   . PRO B 1 122 ? 28.974  86.783 38.337  1.00 0.51 ? 122 PRO B O   1 
ATOM 4162 C CB  . PRO B 1 122 ? 29.767  89.889 37.514  1.00 0.51 ? 122 PRO B CB  1 
ATOM 4163 C CG  . PRO B 1 122 ? 29.605  91.091 38.448  1.00 0.51 ? 122 PRO B CG  1 
ATOM 4164 C CD  . PRO B 1 122 ? 28.096  91.335 38.447  1.00 0.51 ? 122 PRO B CD  1 
ATOM 4165 N N   . TYR B 1 123 ? 28.482  88.173 40.042  1.00 0.24 ? 123 TYR B N   1 
ATOM 4166 C CA  . TYR B 1 123 ? 28.521  87.200 41.111  1.00 0.24 ? 123 TYR B CA  1 
ATOM 4167 C C   . TYR B 1 123 ? 27.179  87.222 41.831  1.00 0.24 ? 123 TYR B C   1 
ATOM 4168 O O   . TYR B 1 123 ? 26.549  88.270 41.946  1.00 0.24 ? 123 TYR B O   1 
ATOM 4169 C CB  . TYR B 1 123 ? 29.735  87.408 42.063  1.00 0.24 ? 123 TYR B CB  1 
ATOM 4170 C CG  . TYR B 1 123 ? 29.772  88.783 42.678  1.00 0.24 ? 123 TYR B CG  1 
ATOM 4171 C CD1 . TYR B 1 123 ? 29.038  89.051 43.844  1.00 0.24 ? 123 TYR B CD1 1 
ATOM 4172 C CD2 . TYR B 1 123 ? 30.529  89.817 42.103  1.00 0.24 ? 123 TYR B CD2 1 
ATOM 4173 C CE1 . TYR B 1 123 ? 29.044  90.329 44.414  1.00 0.24 ? 123 TYR B CE1 1 
ATOM 4174 C CE2 . TYR B 1 123 ? 30.539  91.098 42.677  1.00 0.24 ? 123 TYR B CE2 1 
ATOM 4175 C CZ  . TYR B 1 123 ? 29.787  91.354 43.827  1.00 0.24 ? 123 TYR B CZ  1 
ATOM 4176 O OH  . TYR B 1 123 ? 29.762  92.636 44.408  1.00 0.24 ? 123 TYR B OH  1 
ATOM 4177 N N   . GLY B 1 124 ? 26.694  86.054 42.307  1.00 0.29 ? 124 GLY B N   1 
ATOM 4178 C CA  . GLY B 1 124 ? 25.341  85.930 42.855  1.00 0.29 ? 124 GLY B CA  1 
ATOM 4179 C C   . GLY B 1 124 ? 25.097  86.516 44.223  1.00 0.29 ? 124 GLY B C   1 
ATOM 4180 O O   . GLY B 1 124 ? 24.010  87.009 44.527  1.00 0.29 ? 124 GLY B O   1 
ATOM 4181 N N   . ALA B 1 125 ? 26.110  86.489 45.104  1.00 0.43 ? 125 ALA B N   1 
ATOM 4182 C CA  . ALA B 1 125 ? 26.002  87.053 46.425  1.00 0.43 ? 125 ALA B CA  1 
ATOM 4183 C C   . ALA B 1 125 ? 27.392  87.398 46.928  1.00 0.43 ? 125 ALA B C   1 
ATOM 4184 O O   . ALA B 1 125 ? 28.378  86.827 46.472  1.00 0.43 ? 125 ALA B O   1 
ATOM 4185 C CB  . ALA B 1 125 ? 25.312  86.064 47.394  1.00 0.43 ? 125 ALA B CB  1 
ATOM 4186 N N   . ASN B 1 126 ? 27.492  88.367 47.869  1.00 0.36 ? 126 ASN B N   1 
ATOM 4187 C CA  . ASN B 1 126 ? 28.746  88.871 48.416  1.00 0.36 ? 126 ASN B CA  1 
ATOM 4188 C C   . ASN B 1 126 ? 29.424  87.950 49.437  1.00 0.36 ? 126 ASN B C   1 
ATOM 4189 O O   . ASN B 1 126 ? 30.631  88.001 49.636  1.00 0.36 ? 126 ASN B O   1 
ATOM 4190 C CB  . ASN B 1 126 ? 28.446  90.256 49.068  1.00 0.36 ? 126 ASN B CB  1 
ATOM 4191 C CG  . ASN B 1 126 ? 29.701  91.000 49.533  1.00 0.36 ? 126 ASN B CG  1 
ATOM 4192 O OD1 . ASN B 1 126 ? 30.604  91.269 48.746  1.00 0.36 ? 126 ASN B OD1 1 
ATOM 4193 N ND2 . ASN B 1 126 ? 29.756  91.373 50.834  1.00 0.36 ? 126 ASN B ND2 1 
ATOM 4194 N N   . LYS B 1 127 ? 28.654  87.112 50.160  1.00 0.42 ? 127 LYS B N   1 
ATOM 4195 C CA  . LYS B 1 127 ? 29.204  86.289 51.226  1.00 0.42 ? 127 LYS B CA  1 
ATOM 4196 C C   . LYS B 1 127 ? 30.102  85.147 50.763  1.00 0.42 ? 127 LYS B C   1 
ATOM 4197 O O   . LYS B 1 127 ? 31.183  84.943 51.309  1.00 0.42 ? 127 LYS B O   1 
ATOM 4198 C CB  . LYS B 1 127 ? 28.060  85.718 52.095  1.00 0.42 ? 127 LYS B CB  1 
ATOM 4199 C CG  . LYS B 1 127 ? 27.302  86.795 52.892  1.00 0.42 ? 127 LYS B CG  1 
ATOM 4200 C CD  . LYS B 1 127 ? 26.361  86.197 53.957  1.00 0.42 ? 127 LYS B CD  1 
ATOM 4201 C CE  . LYS B 1 127 ? 25.145  85.424 53.427  1.00 0.42 ? 127 LYS B CE  1 
ATOM 4202 N NZ  . LYS B 1 127 ? 24.114  86.368 52.940  1.00 0.42 ? 127 LYS B NZ  1 
ATOM 4203 N N   . ASP B 1 128 ? 29.671  84.385 49.738  1.00 0.39 ? 128 ASP B N   1 
ATOM 4204 C CA  . ASP B 1 128 ? 30.467  83.339 49.136  1.00 0.39 ? 128 ASP B CA  1 
ATOM 4205 C C   . ASP B 1 128 ? 31.510  83.908 48.181  1.00 0.39 ? 128 ASP B C   1 
ATOM 4206 O O   . ASP B 1 128 ? 31.220  84.708 47.293  1.00 0.39 ? 128 ASP B O   1 
ATOM 4207 C CB  . ASP B 1 128 ? 29.596  82.341 48.340  1.00 0.39 ? 128 ASP B CB  1 
ATOM 4208 C CG  . ASP B 1 128 ? 28.653  81.551 49.224  1.00 0.39 ? 128 ASP B CG  1 
ATOM 4209 O OD1 . ASP B 1 128 ? 28.998  81.300 50.404  1.00 0.39 ? 128 ASP B OD1 1 
ATOM 4210 O OD2 . ASP B 1 128 ? 27.593  81.135 48.695  1.00 0.39 ? 128 ASP B OD2 1 
ATOM 4211 N N   . GLY B 1 129 ? 32.778  83.485 48.333  1.00 0.55 ? 129 GLY B N   1 
ATOM 4212 C CA  . GLY B 1 129 ? 33.898  84.077 47.613  1.00 0.55 ? 129 GLY B CA  1 
ATOM 4213 C C   . GLY B 1 129 ? 34.193  83.445 46.281  1.00 0.55 ? 129 GLY B C   1 
ATOM 4214 O O   . GLY B 1 129 ? 34.717  82.335 46.218  1.00 0.55 ? 129 GLY B O   1 
ATOM 4215 N N   . ILE B 1 130 ? 33.896  84.148 45.169  1.00 0.49 ? 130 ILE B N   1 
ATOM 4216 C CA  . ILE B 1 130 ? 34.352  83.778 43.830  1.00 0.49 ? 130 ILE B CA  1 
ATOM 4217 C C   . ILE B 1 130 ? 35.850  84.035 43.696  1.00 0.49 ? 130 ILE B C   1 
ATOM 4218 O O   . ILE B 1 130 ? 36.360  85.049 44.164  1.00 0.49 ? 130 ILE B O   1 
ATOM 4219 C CB  . ILE B 1 130 ? 33.547  84.464 42.720  1.00 0.49 ? 130 ILE B CB  1 
ATOM 4220 C CG1 . ILE B 1 130 ? 32.021  84.251 42.908  1.00 0.49 ? 130 ILE B CG1 1 
ATOM 4221 C CG2 . ILE B 1 130 ? 33.996  83.998 41.314  1.00 0.49 ? 130 ILE B CG2 1 
ATOM 4222 C CD1 . ILE B 1 130 ? 31.590  82.784 43.027  1.00 0.49 ? 130 ILE B CD1 1 
ATOM 4223 N N   . ILE B 1 131 ? 36.606  83.084 43.102  1.00 0.50 ? 131 ILE B N   1 
ATOM 4224 C CA  . ILE B 1 131 ? 38.067  83.119 43.149  1.00 0.50 ? 131 ILE B CA  1 
ATOM 4225 C C   . ILE B 1 131 ? 38.688  83.566 41.823  1.00 0.50 ? 131 ILE B C   1 
ATOM 4226 O O   . ILE B 1 131 ? 39.850  83.954 41.758  1.00 0.50 ? 131 ILE B O   1 
ATOM 4227 C CB  . ILE B 1 131 ? 38.542  81.746 43.636  1.00 0.50 ? 131 ILE B CB  1 
ATOM 4228 C CG1 . ILE B 1 131 ? 38.025  81.555 45.088  1.00 0.50 ? 131 ILE B CG1 1 
ATOM 4229 C CG2 . ILE B 1 131 ? 40.079  81.587 43.585  1.00 0.50 ? 131 ILE B CG2 1 
ATOM 4230 C CD1 . ILE B 1 131 ? 38.158  80.137 45.639  1.00 0.50 ? 131 ILE B CD1 1 
ATOM 4231 N N   . TRP B 1 132 ? 37.899  83.582 40.730  1.00 0.37 ? 132 TRP B N   1 
ATOM 4232 C CA  . TRP B 1 132 ? 38.222  84.216 39.450  1.00 0.37 ? 132 TRP B CA  1 
ATOM 4233 C C   . TRP B 1 132 ? 39.423  83.649 38.668  1.00 0.37 ? 132 TRP B C   1 
ATOM 4234 O O   . TRP B 1 132 ? 39.830  84.194 37.646  1.00 0.37 ? 132 TRP B O   1 
ATOM 4235 C CB  . TRP B 1 132 ? 38.326  85.766 39.561  1.00 0.37 ? 132 TRP B CB  1 
ATOM 4236 C CG  . TRP B 1 132 ? 37.232  86.460 40.367  1.00 0.37 ? 132 TRP B CG  1 
ATOM 4237 C CD1 . TRP B 1 132 ? 37.325  86.893 41.660  1.00 0.37 ? 132 TRP B CD1 1 
ATOM 4238 C CD2 . TRP B 1 132 ? 35.903  86.811 39.926  1.00 0.37 ? 132 TRP B CD2 1 
ATOM 4239 N NE1 . TRP B 1 132 ? 36.142  87.470 42.059  1.00 0.37 ? 132 TRP B NE1 1 
ATOM 4240 C CE2 . TRP B 1 132 ? 35.258  87.433 41.017  1.00 0.37 ? 132 TRP B CE2 1 
ATOM 4241 C CE3 . TRP B 1 132 ? 35.241  86.641 38.714  1.00 0.37 ? 132 TRP B CE3 1 
ATOM 4242 C CZ2 . TRP B 1 132 ? 33.949  87.881 40.917  1.00 0.37 ? 132 TRP B CZ2 1 
ATOM 4243 C CZ3 . TRP B 1 132 ? 33.920  87.108 38.612  1.00 0.37 ? 132 TRP B CZ3 1 
ATOM 4244 C CH2 . TRP B 1 132 ? 33.277  87.712 39.700  1.00 0.37 ? 132 TRP B CH2 1 
ATOM 4245 N N   . VAL B 1 133 ? 40.000  82.502 39.082  1.00 0.39 ? 133 VAL B N   1 
ATOM 4246 C CA  . VAL B 1 133 ? 41.080  81.832 38.366  1.00 0.39 ? 133 VAL B CA  1 
ATOM 4247 C C   . VAL B 1 133 ? 40.592  81.039 37.152  1.00 0.39 ? 133 VAL B C   1 
ATOM 4248 O O   . VAL B 1 133 ? 39.725  80.173 37.254  1.00 0.39 ? 133 VAL B O   1 
ATOM 4249 C CB  . VAL B 1 133 ? 41.945  80.947 39.278  1.00 0.39 ? 133 VAL B CB  1 
ATOM 4250 C CG1 . VAL B 1 133 ? 42.728  81.841 40.261  1.00 0.39 ? 133 VAL B CG1 1 
ATOM 4251 C CG2 . VAL B 1 133 ? 41.113  79.898 40.048  1.00 0.39 ? 133 VAL B CG2 1 
ATOM 4252 N N   . ALA B 1 134 ? 41.146  81.332 35.953  1.00 0.54 ? 134 ALA B N   1 
ATOM 4253 C CA  . ALA B 1 134 ? 40.862  80.579 34.750  1.00 0.54 ? 134 ALA B CA  1 
ATOM 4254 C C   . ALA B 1 134 ? 41.953  80.826 33.714  1.00 0.54 ? 134 ALA B C   1 
ATOM 4255 O O   . ALA B 1 134 ? 42.800  81.706 33.865  1.00 0.54 ? 134 ALA B O   1 
ATOM 4256 C CB  . ALA B 1 134 ? 39.480  80.928 34.154  1.00 0.54 ? 134 ALA B CB  1 
ATOM 4257 N N   . THR B 1 135 ? 41.986  79.995 32.652  1.00 0.52 ? 135 THR B N   1 
ATOM 4258 C CA  . THR B 1 135 ? 42.846  80.146 31.484  1.00 0.52 ? 135 THR B CA  1 
ATOM 4259 C C   . THR B 1 135 ? 42.440  81.321 30.596  1.00 0.52 ? 135 THR B C   1 
ATOM 4260 O O   . THR B 1 135 ? 41.274  81.497 30.269  1.00 0.52 ? 135 THR B O   1 
ATOM 4261 C CB  . THR B 1 135 ? 42.881  78.873 30.626  1.00 0.52 ? 135 THR B CB  1 
ATOM 4262 O OG1 . THR B 1 135 ? 41.573  78.402 30.329  1.00 0.52 ? 135 THR B OG1 1 
ATOM 4263 C CG2 . THR B 1 135 ? 43.552  77.731 31.402  1.00 0.52 ? 135 THR B CG2 1 
ATOM 4264 N N   . GLU B 1 136 ? 43.420  82.128 30.120  1.00 0.48 ? 136 GLU B N   1 
ATOM 4265 C CA  . GLU B 1 136 ? 43.216  83.297 29.251  1.00 0.48 ? 136 GLU B CA  1 
ATOM 4266 C C   . GLU B 1 136 ? 42.605  82.965 27.889  1.00 0.48 ? 136 GLU B C   1 
ATOM 4267 O O   . GLU B 1 136 ? 41.927  83.762 27.245  1.00 0.48 ? 136 GLU B O   1 
ATOM 4268 C CB  . GLU B 1 136 ? 44.587  84.002 29.050  1.00 0.48 ? 136 GLU B CB  1 
ATOM 4269 C CG  . GLU B 1 136 ? 44.613  85.282 28.167  1.00 0.48 ? 136 GLU B CG  1 
ATOM 4270 C CD  . GLU B 1 136 ? 43.989  86.505 28.838  1.00 0.48 ? 136 GLU B CD  1 
ATOM 4271 O OE1 . GLU B 1 136 ? 43.499  86.369 29.988  1.00 0.48 ? 136 GLU B OE1 1 
ATOM 4272 O OE2 . GLU B 1 136 ? 44.097  87.600 28.230  1.00 0.48 ? 136 GLU B OE2 1 
ATOM 4273 N N   . GLY B 1 137 ? 42.817  81.717 27.424  1.00 0.51 ? 137 GLY B N   1 
ATOM 4274 C CA  . GLY B 1 137 ? 42.273  81.214 26.171  1.00 0.51 ? 137 GLY B CA  1 
ATOM 4275 C C   . GLY B 1 137 ? 40.813  80.831 26.191  1.00 0.51 ? 137 GLY B C   1 
ATOM 4276 O O   . GLY B 1 137 ? 40.308  80.359 25.178  1.00 0.51 ? 137 GLY B O   1 
ATOM 4277 N N   . ALA B 1 138 ? 40.098  80.979 27.329  1.00 0.54 ? 138 ALA B N   1 
ATOM 4278 C CA  . ALA B 1 138 ? 38.659  80.793 27.398  1.00 0.54 ? 138 ALA B CA  1 
ATOM 4279 C C   . ALA B 1 138 ? 37.897  81.735 26.465  1.00 0.54 ? 138 ALA B C   1 
ATOM 4280 O O   . ALA B 1 138 ? 38.219  82.913 26.341  1.00 0.54 ? 138 ALA B O   1 
ATOM 4281 C CB  . ALA B 1 138 ? 38.176  80.975 28.852  1.00 0.54 ? 138 ALA B CB  1 
ATOM 4282 N N   . LEU B 1 139 ? 36.873  81.234 25.755  1.00 0.42 ? 139 LEU B N   1 
ATOM 4283 C CA  . LEU B 1 139 ? 36.275  81.925 24.630  1.00 0.42 ? 139 LEU B CA  1 
ATOM 4284 C C   . LEU B 1 139 ? 34.996  82.640 25.042  1.00 0.42 ? 139 LEU B C   1 
ATOM 4285 O O   . LEU B 1 139 ? 34.497  83.521 24.340  1.00 0.42 ? 139 LEU B O   1 
ATOM 4286 C CB  . LEU B 1 139 ? 36.002  80.871 23.527  1.00 0.42 ? 139 LEU B CB  1 
ATOM 4287 C CG  . LEU B 1 139 ? 35.615  81.401 22.130  1.00 0.42 ? 139 LEU B CG  1 
ATOM 4288 C CD1 . LEU B 1 139 ? 36.713  82.285 21.516  1.00 0.42 ? 139 LEU B CD1 1 
ATOM 4289 C CD2 . LEU B 1 139 ? 35.306  80.229 21.182  1.00 0.42 ? 139 LEU B CD2 1 
ATOM 4290 N N   . ASN B 1 140 ? 34.473  82.306 26.237  1.00 0.49 ? 140 ASN B N   1 
ATOM 4291 C CA  . ASN B 1 140 ? 33.372  82.970 26.908  1.00 0.49 ? 140 ASN B CA  1 
ATOM 4292 C C   . ASN B 1 140 ? 32.041  82.896 26.143  1.00 0.49 ? 140 ASN B C   1 
ATOM 4293 O O   . ASN B 1 140 ? 31.276  83.863 26.110  1.00 0.49 ? 140 ASN B O   1 
ATOM 4294 C CB  . ASN B 1 140 ? 33.727  84.437 27.291  1.00 0.49 ? 140 ASN B CB  1 
ATOM 4295 C CG  . ASN B 1 140 ? 34.963  84.474 28.183  1.00 0.49 ? 140 ASN B CG  1 
ATOM 4296 O OD1 . ASN B 1 140 ? 34.878  84.041 29.334  1.00 0.49 ? 140 ASN B OD1 1 
ATOM 4297 N ND2 . ASN B 1 140 ? 36.095  85.033 27.700  1.00 0.49 ? 140 ASN B ND2 1 
ATOM 4298 N N   . THR B 1 141 ? 31.742  81.743 25.499  1.00 0.40 ? 141 THR B N   1 
ATOM 4299 C CA  . THR B 1 141 ? 30.563  81.524 24.654  1.00 0.40 ? 141 THR B CA  1 
ATOM 4300 C C   . THR B 1 141 ? 29.241  81.444 25.416  1.00 0.40 ? 141 THR B C   1 
ATOM 4301 O O   . THR B 1 141 ? 29.195  80.927 26.533  1.00 0.40 ? 141 THR B O   1 
ATOM 4302 C CB  . THR B 1 141 ? 30.651  80.344 23.671  1.00 0.40 ? 141 THR B CB  1 
ATOM 4303 O OG1 . THR B 1 141 ? 30.690  79.065 24.285  1.00 0.40 ? 141 THR B OG1 1 
ATOM 4304 C CG2 . THR B 1 141 ? 31.913  80.499 22.809  1.00 0.40 ? 141 THR B CG2 1 
ATOM 4305 N N   . PRO B 1 142 ? 28.113  81.930 24.896  1.00 0.37 ? 142 PRO B N   1 
ATOM 4306 C CA  . PRO B 1 142 ? 26.832  81.742 25.562  1.00 0.37 ? 142 PRO B CA  1 
ATOM 4307 C C   . PRO B 1 142 ? 26.233  80.371 25.279  1.00 0.37 ? 142 PRO B C   1 
ATOM 4308 O O   . PRO B 1 142 ? 26.225  79.920 24.132  1.00 0.37 ? 142 PRO B O   1 
ATOM 4309 C CB  . PRO B 1 142 ? 25.961  82.871 24.987  1.00 0.37 ? 142 PRO B CB  1 
ATOM 4310 C CG  . PRO B 1 142 ? 26.538  83.137 23.594  1.00 0.37 ? 142 PRO B CG  1 
ATOM 4311 C CD  . PRO B 1 142 ? 28.029  82.854 23.766  1.00 0.37 ? 142 PRO B CD  1 
ATOM 4312 N N   . LYS B 1 143 ? 25.680  79.695 26.307  1.00 0.38 ? 143 LYS B N   1 
ATOM 4313 C CA  . LYS B 1 143 ? 24.966  78.450 26.111  1.00 0.38 ? 143 LYS B CA  1 
ATOM 4314 C C   . LYS B 1 143 ? 23.965  78.265 27.246  1.00 0.38 ? 143 LYS B C   1 
ATOM 4315 O O   . LYS B 1 143 ? 24.177  78.766 28.349  1.00 0.38 ? 143 LYS B O   1 
ATOM 4316 C CB  . LYS B 1 143 ? 25.946  77.246 26.030  1.00 0.38 ? 143 LYS B CB  1 
ATOM 4317 C CG  . LYS B 1 143 ? 25.303  75.958 25.494  1.00 0.38 ? 143 LYS B CG  1 
ATOM 4318 C CD  . LYS B 1 143 ? 26.317  74.872 25.091  1.00 0.38 ? 143 LYS B CD  1 
ATOM 4319 C CE  . LYS B 1 143 ? 25.618  73.641 24.500  1.00 0.38 ? 143 LYS B CE  1 
ATOM 4320 N NZ  . LYS B 1 143 ? 26.581  72.616 24.042  1.00 0.38 ? 143 LYS B NZ  1 
ATOM 4321 N N   . ASP B 1 144 ? 22.829  77.565 27.005  1.00 0.37 ? 144 ASP B N   1 
ATOM 4322 C CA  . ASP B 1 144 ? 21.799  77.289 27.999  1.00 0.37 ? 144 ASP B CA  1 
ATOM 4323 C C   . ASP B 1 144 ? 22.223  76.188 28.979  1.00 0.37 ? 144 ASP B C   1 
ATOM 4324 O O   . ASP B 1 144 ? 22.021  76.261 30.190  1.00 0.37 ? 144 ASP B O   1 
ATOM 4325 C CB  . ASP B 1 144 ? 20.467  76.891 27.293  1.00 0.37 ? 144 ASP B CB  1 
ATOM 4326 C CG  . ASP B 1 144 ? 19.890  77.974 26.402  1.00 0.37 ? 144 ASP B CG  1 
ATOM 4327 O OD1 . ASP B 1 144 ? 20.298  79.159 26.454  1.00 0.37 ? 144 ASP B OD1 1 
ATOM 4328 O OD2 . ASP B 1 144 ? 18.978  77.667 25.588  1.00 0.37 ? 144 ASP B OD2 1 
ATOM 4329 N N   . HIS B 1 145 ? 22.871  75.133 28.446  1.00 0.49 ? 145 HIS B N   1 
ATOM 4330 C CA  . HIS B 1 145 ? 23.085  73.844 29.081  1.00 0.49 ? 145 HIS B CA  1 
ATOM 4331 C C   . HIS B 1 145 ? 24.042  73.798 30.262  1.00 0.49 ? 145 HIS B C   1 
ATOM 4332 O O   . HIS B 1 145 ? 24.057  72.821 31.005  1.00 0.49 ? 145 HIS B O   1 
ATOM 4333 C CB  . HIS B 1 145 ? 23.679  72.849 28.044  1.00 0.49 ? 145 HIS B CB  1 
ATOM 4334 C CG  . HIS B 1 145 ? 22.861  72.609 26.809  1.00 0.49 ? 145 HIS B CG  1 
ATOM 4335 N ND1 . HIS B 1 145 ? 22.574  73.642 25.933  1.00 0.49 ? 145 HIS B ND1 1 
ATOM 4336 C CD2 . HIS B 1 145 ? 22.357  71.441 26.337  1.00 0.49 ? 145 HIS B CD2 1 
ATOM 4337 C CE1 . HIS B 1 145 ? 21.882  73.079 24.960  1.00 0.49 ? 145 HIS B CE1 1 
ATOM 4338 N NE2 . HIS B 1 145 ? 21.728  71.748 25.153  1.00 0.49 ? 145 HIS B NE2 1 
ATOM 4339 N N   . ILE B 1 146 ? 24.901  74.819 30.434  1.00 0.59 ? 146 ILE B N   1 
ATOM 4340 C CA  . ILE B 1 146 ? 26.032  74.763 31.343  1.00 0.59 ? 146 ILE B CA  1 
ATOM 4341 C C   . ILE B 1 146 ? 25.766  75.408 32.679  1.00 0.59 ? 146 ILE B C   1 
ATOM 4342 O O   . ILE B 1 146 ? 26.506  75.198 33.635  1.00 0.59 ? 146 ILE B O   1 
ATOM 4343 C CB  . ILE B 1 146 ? 27.243  75.472 30.736  1.00 0.59 ? 146 ILE B CB  1 
ATOM 4344 C CG1 . ILE B 1 146 ? 27.007  76.989 30.483  1.00 0.59 ? 146 ILE B CG1 1 
ATOM 4345 C CG2 . ILE B 1 146 ? 27.643  74.705 29.458  1.00 0.59 ? 146 ILE B CG2 1 
ATOM 4346 C CD1 . ILE B 1 146 ? 28.223  77.723 29.901  1.00 0.59 ? 146 ILE B CD1 1 
ATOM 4347 N N   . GLY B 1 147 ? 24.690  76.216 32.798  1.00 0.58 ? 147 GLY B N   1 
ATOM 4348 C CA  . GLY B 1 147 ? 24.476  76.960 34.026  1.00 0.58 ? 147 GLY B CA  1 
ATOM 4349 C C   . GLY B 1 147 ? 23.970  76.102 35.118  1.00 0.58 ? 147 GLY B C   1 
ATOM 4350 O O   . GLY B 1 147 ? 24.552  76.083 36.199  1.00 0.58 ? 147 GLY B O   1 
ATOM 4351 N N   . THR B 1 148 ? 22.869  75.365 34.867  1.00 0.52 ? 148 THR B N   1 
ATOM 4352 C CA  . THR B 1 148 ? 22.205  74.591 35.893  1.00 0.52 ? 148 THR B CA  1 
ATOM 4353 C C   . THR B 1 148 ? 21.412  73.394 35.295  1.00 0.52 ? 148 THR B C   1 
ATOM 4354 O O   . THR B 1 148 ? 21.434  73.196 34.076  1.00 0.52 ? 148 THR B O   1 
ATOM 4355 C CB  . THR B 1 148 ? 21.364  75.420 36.865  1.00 0.52 ? 148 THR B CB  1 
ATOM 4356 O OG1 . THR B 1 148 ? 20.190  75.798 36.257  1.00 0.52 ? 148 THR B OG1 1 
ATOM 4357 C CG2 . THR B 1 148 ? 21.988  76.711 37.456  1.00 0.52 ? 148 THR B CG2 1 
ATOM 4358 N N   . ARG B 1 149 ? 20.732  72.508 36.089  1.00 0.44 ? 149 ARG B N   1 
ATOM 4359 C CA  . ARG B 1 149 ? 19.975  71.313 35.666  1.00 0.44 ? 149 ARG B CA  1 
ATOM 4360 C C   . ARG B 1 149 ? 18.670  71.611 34.950  1.00 0.44 ? 149 ARG B C   1 
ATOM 4361 O O   . ARG B 1 149 ? 17.706  72.129 35.510  1.00 0.44 ? 149 ARG B O   1 
ATOM 4362 C CB  . ARG B 1 149 ? 19.600  70.411 36.887  1.00 0.44 ? 149 ARG B CB  1 
ATOM 4363 C CG  . ARG B 1 149 ? 18.923  69.031 36.693  1.00 0.44 ? 149 ARG B CG  1 
ATOM 4364 C CD  . ARG B 1 149 ? 18.641  68.347 38.050  1.00 0.44 ? 149 ARG B CD  1 
ATOM 4365 N NE  . ARG B 1 149 ? 19.949  67.904 38.635  1.00 0.44 ? 149 ARG B NE  1 
ATOM 4366 C CZ  . ARG B 1 149 ? 20.193  67.655 39.930  1.00 0.44 ? 149 ARG B CZ  1 
ATOM 4367 N NH1 . ARG B 1 149 ? 21.350  67.074 40.228  1.00 0.44 ? 149 ARG B NH1 1 
ATOM 4368 N NH2 . ARG B 1 149 ? 19.348  67.962 40.904  1.00 0.44 ? 149 ARG B NH2 1 
ATOM 4369 N N   . ASN B 1 150 ? 18.587  71.175 33.686  1.00 0.45 ? 150 ASN B N   1 
ATOM 4370 C CA  . ASN B 1 150 ? 17.396  71.246 32.886  1.00 0.45 ? 150 ASN B CA  1 
ATOM 4371 C C   . ASN B 1 150 ? 17.429  70.027 31.989  1.00 0.45 ? 150 ASN B C   1 
ATOM 4372 O O   . ASN B 1 150 ? 18.516  69.488 31.787  1.00 0.45 ? 150 ASN B O   1 
ATOM 4373 C CB  . ASN B 1 150 ? 17.418  72.505 31.993  1.00 0.45 ? 150 ASN B CB  1 
ATOM 4374 C CG  . ASN B 1 150 ? 16.898  73.696 32.770  1.00 0.45 ? 150 ASN B CG  1 
ATOM 4375 O OD1 . ASN B 1 150 ? 17.671  74.552 33.183  1.00 0.45 ? 150 ASN B OD1 1 
ATOM 4376 N ND2 . ASN B 1 150 ? 15.563  73.797 32.959  1.00 0.45 ? 150 ASN B ND2 1 
ATOM 4377 N N   . PRO B 1 151 ? 16.320  69.570 31.402  1.00 0.33 ? 151 PRO B N   1 
ATOM 4378 C CA  . PRO B 1 151 ? 16.280  68.326 30.627  1.00 0.33 ? 151 PRO B CA  1 
ATOM 4379 C C   . PRO B 1 151 ? 17.088  68.318 29.340  1.00 0.33 ? 151 PRO B C   1 
ATOM 4380 O O   . PRO B 1 151 ? 17.208  67.272 28.715  1.00 0.33 ? 151 PRO B O   1 
ATOM 4381 C CB  . PRO B 1 151 ? 14.792  68.165 30.280  1.00 0.33 ? 151 PRO B CB  1 
ATOM 4382 C CG  . PRO B 1 151 ? 14.057  68.862 31.421  1.00 0.33 ? 151 PRO B CG  1 
ATOM 4383 C CD  . PRO B 1 151 ? 14.970  70.038 31.740  1.00 0.33 ? 151 PRO B CD  1 
ATOM 4384 N N   . ALA B 1 152 ? 17.645  69.470 28.924  1.00 0.39 ? 152 ALA B N   1 
ATOM 4385 C CA  . ALA B 1 152 ? 18.511  69.606 27.779  1.00 0.39 ? 152 ALA B CA  1 
ATOM 4386 C C   . ALA B 1 152 ? 19.910  69.031 28.005  1.00 0.39 ? 152 ALA B C   1 
ATOM 4387 O O   . ALA B 1 152 ? 20.671  68.871 27.053  1.00 0.39 ? 152 ALA B O   1 
ATOM 4388 C CB  . ALA B 1 152 ? 18.634  71.108 27.448  1.00 0.39 ? 152 ALA B CB  1 
ATOM 4389 N N   . ASN B 1 153 ? 20.293  68.727 29.264  1.00 0.47 ? 153 ASN B N   1 
ATOM 4390 C CA  . ASN B 1 153 ? 21.613  68.235 29.595  1.00 0.47 ? 153 ASN B CA  1 
ATOM 4391 C C   . ASN B 1 153 ? 21.498  67.126 30.639  1.00 0.47 ? 153 ASN B C   1 
ATOM 4392 O O   . ASN B 1 153 ? 20.468  66.952 31.287  1.00 0.47 ? 153 ASN B O   1 
ATOM 4393 C CB  . ASN B 1 153 ? 22.471  69.420 30.126  1.00 0.47 ? 153 ASN B CB  1 
ATOM 4394 C CG  . ASN B 1 153 ? 23.970  69.133 30.120  1.00 0.47 ? 153 ASN B CG  1 
ATOM 4395 O OD1 . ASN B 1 153 ? 24.445  68.098 29.647  1.00 0.47 ? 153 ASN B OD1 1 
ATOM 4396 N ND2 . ASN B 1 153 ? 24.760  70.097 30.645  1.00 0.47 ? 153 ASN B ND2 1 
ATOM 4397 N N   . ASN B 1 154 ? 22.584  66.346 30.826  1.00 0.45 ? 154 ASN B N   1 
ATOM 4398 C CA  . ASN B 1 154 ? 22.724  65.359 31.886  1.00 0.45 ? 154 ASN B CA  1 
ATOM 4399 C C   . ASN B 1 154 ? 22.636  66.000 33.266  1.00 0.45 ? 154 ASN B C   1 
ATOM 4400 O O   . ASN B 1 154 ? 23.048  67.136 33.482  1.00 0.45 ? 154 ASN B O   1 
ATOM 4401 C CB  . ASN B 1 154 ? 24.047  64.558 31.768  1.00 0.45 ? 154 ASN B CB  1 
ATOM 4402 C CG  . ASN B 1 154 ? 24.019  63.727 30.493  1.00 0.45 ? 154 ASN B CG  1 
ATOM 4403 O OD1 . ASN B 1 154 ? 23.016  63.096 30.165  1.00 0.45 ? 154 ASN B OD1 1 
ATOM 4404 N ND2 . ASN B 1 154 ? 25.152  63.688 29.758  1.00 0.45 ? 154 ASN B ND2 1 
ATOM 4405 N N   . ALA B 1 155 ? 22.079  65.280 34.261  1.00 0.45 ? 155 ALA B N   1 
ATOM 4406 C CA  . ALA B 1 155 ? 21.632  65.891 35.501  1.00 0.45 ? 155 ALA B CA  1 
ATOM 4407 C C   . ALA B 1 155 ? 22.716  66.309 36.506  1.00 0.45 ? 155 ALA B C   1 
ATOM 4408 O O   . ALA B 1 155 ? 22.404  66.853 37.572  1.00 0.45 ? 155 ALA B O   1 
ATOM 4409 C CB  . ALA B 1 155 ? 20.629  64.934 36.179  1.00 0.45 ? 155 ALA B CB  1 
ATOM 4410 N N   . ALA B 1 156 ? 24.005  66.068 36.204  1.00 0.53 ? 156 ALA B N   1 
ATOM 4411 C CA  . ALA B 1 156 ? 25.106  66.458 37.049  1.00 0.53 ? 156 ALA B CA  1 
ATOM 4412 C C   . ALA B 1 156 ? 26.371  66.647 36.226  1.00 0.53 ? 156 ALA B C   1 
ATOM 4413 O O   . ALA B 1 156 ? 26.563  65.968 35.217  1.00 0.53 ? 156 ALA B O   1 
ATOM 4414 C CB  . ALA B 1 156 ? 25.364  65.386 38.130  1.00 0.53 ? 156 ALA B CB  1 
ATOM 4415 N N   . ILE B 1 157 ? 27.265  67.558 36.664  1.00 0.57 ? 157 ILE B N   1 
ATOM 4416 C CA  . ILE B 1 157 ? 28.510  67.901 35.992  1.00 0.57 ? 157 ILE B CA  1 
ATOM 4417 C C   . ILE B 1 157 ? 29.686  67.547 36.888  1.00 0.57 ? 157 ILE B C   1 
ATOM 4418 O O   . ILE B 1 157 ? 29.779  68.013 38.023  1.00 0.57 ? 157 ILE B O   1 
ATOM 4419 C CB  . ILE B 1 157 ? 28.620  69.401 35.723  1.00 0.57 ? 157 ILE B CB  1 
ATOM 4420 C CG1 . ILE B 1 157 ? 27.408  69.978 34.950  1.00 0.57 ? 157 ILE B CG1 1 
ATOM 4421 C CG2 . ILE B 1 157 ? 29.953  69.749 35.017  1.00 0.57 ? 157 ILE B CG2 1 
ATOM 4422 C CD1 . ILE B 1 157 ? 27.172  69.385 33.561  1.00 0.57 ? 157 ILE B CD1 1 
ATOM 4423 N N   . VAL B 1 158 ? 30.631  66.729 36.382  1.00 0.60 ? 158 VAL B N   1 
ATOM 4424 C CA  . VAL B 1 158 ? 31.850  66.348 37.089  1.00 0.60 ? 158 VAL B CA  1 
ATOM 4425 C C   . VAL B 1 158 ? 32.988  67.251 36.658  1.00 0.60 ? 158 VAL B C   1 
ATOM 4426 O O   . VAL B 1 158 ? 33.231  67.442 35.467  1.00 0.60 ? 158 VAL B O   1 
ATOM 4427 C CB  . VAL B 1 158 ? 32.245  64.881 36.851  1.00 0.60 ? 158 VAL B CB  1 
ATOM 4428 C CG1 . VAL B 1 158 ? 33.703  64.551 37.256  1.00 0.60 ? 158 VAL B CG1 1 
ATOM 4429 C CG2 . VAL B 1 158 ? 31.294  63.987 37.664  1.00 0.60 ? 158 VAL B CG2 1 
ATOM 4430 N N   . LEU B 1 159 ? 33.719  67.807 37.640  1.00 0.61 ? 159 LEU B N   1 
ATOM 4431 C CA  . LEU B 1 159 ? 34.929  68.577 37.458  1.00 0.61 ? 159 LEU B CA  1 
ATOM 4432 C C   . LEU B 1 159 ? 36.041  67.897 38.256  1.00 0.61 ? 159 LEU B C   1 
ATOM 4433 O O   . LEU B 1 159 ? 35.805  67.373 39.346  1.00 0.61 ? 159 LEU B O   1 
ATOM 4434 C CB  . LEU B 1 159 ? 34.733  70.053 37.899  1.00 0.61 ? 159 LEU B CB  1 
ATOM 4435 C CG  . LEU B 1 159 ? 33.574  70.772 37.163  1.00 0.61 ? 159 LEU B CG  1 
ATOM 4436 C CD1 . LEU B 1 159 ? 32.250  70.719 37.948  1.00 0.61 ? 159 LEU B CD1 1 
ATOM 4437 C CD2 . LEU B 1 159 ? 33.926  72.235 36.850  1.00 0.61 ? 159 LEU B CD2 1 
ATOM 4438 N N   . GLN B 1 160 ? 37.275  67.814 37.707  1.00 0.63 ? 160 GLN B N   1 
ATOM 4439 C CA  . GLN B 1 160 ? 38.356  67.080 38.336  1.00 0.63 ? 160 GLN B CA  1 
ATOM 4440 C C   . GLN B 1 160 ? 39.708  67.494 37.784  1.00 0.63 ? 160 GLN B C   1 
ATOM 4441 O O   . GLN B 1 160 ? 39.788  68.191 36.774  1.00 0.63 ? 160 GLN B O   1 
ATOM 4442 C CB  . GLN B 1 160 ? 38.169  65.548 38.134  1.00 0.63 ? 160 GLN B CB  1 
ATOM 4443 C CG  . GLN B 1 160 ? 38.126  65.116 36.647  1.00 0.63 ? 160 GLN B CG  1 
ATOM 4444 C CD  . GLN B 1 160 ? 37.660  63.671 36.480  1.00 0.63 ? 160 GLN B CD  1 
ATOM 4445 O OE1 . GLN B 1 160 ? 37.842  62.805 37.340  1.00 0.63 ? 160 GLN B OE1 1 
ATOM 4446 N NE2 . GLN B 1 160 ? 37.032  63.404 35.312  1.00 0.63 ? 160 GLN B NE2 1 
ATOM 4447 N N   . LEU B 1 161 ? 40.809  67.056 38.443  1.00 0.60 ? 161 LEU B N   1 
ATOM 4448 C CA  . LEU B 1 161 ? 42.183  67.348 38.068  1.00 0.60 ? 161 LEU B CA  1 
ATOM 4449 C C   . LEU B 1 161 ? 42.557  66.936 36.630  1.00 0.60 ? 161 LEU B C   1 
ATOM 4450 O O   . LEU B 1 161 ? 42.285  65.793 36.252  1.00 0.60 ? 161 LEU B O   1 
ATOM 4451 C CB  . LEU B 1 161 ? 43.176  66.603 39.009  1.00 0.60 ? 161 LEU B CB  1 
ATOM 4452 C CG  . LEU B 1 161 ? 43.138  67.021 40.496  1.00 0.60 ? 161 LEU B CG  1 
ATOM 4453 C CD1 . LEU B 1 161 ? 43.966  66.050 41.356  1.00 0.60 ? 161 LEU B CD1 1 
ATOM 4454 C CD2 . LEU B 1 161 ? 43.635  68.462 40.702  1.00 0.60 ? 161 LEU B CD2 1 
ATOM 4455 N N   . PRO B 1 162 ? 43.231  67.745 35.808  1.00 0.58 ? 162 PRO B N   1 
ATOM 4456 C CA  . PRO B 1 162 ? 43.444  67.430 34.393  1.00 0.58 ? 162 PRO B CA  1 
ATOM 4457 C C   . PRO B 1 162 ? 44.713  66.609 34.213  1.00 0.58 ? 162 PRO B C   1 
ATOM 4458 O O   . PRO B 1 162 ? 45.551  66.919 33.370  1.00 0.58 ? 162 PRO B O   1 
ATOM 4459 C CB  . PRO B 1 162 ? 43.573  68.827 33.749  1.00 0.58 ? 162 PRO B CB  1 
ATOM 4460 C CG  . PRO B 1 162 ? 44.168  69.707 34.849  1.00 0.58 ? 162 PRO B CG  1 
ATOM 4461 C CD  . PRO B 1 162 ? 43.531  69.145 36.114  1.00 0.58 ? 162 PRO B CD  1 
ATOM 4462 N N   . GLN B 1 163 ? 44.863  65.539 35.019  1.00 0.49 ? 163 GLN B N   1 
ATOM 4463 C CA  . GLN B 1 163 ? 46.001  64.634 35.071  1.00 0.49 ? 163 GLN B CA  1 
ATOM 4464 C C   . GLN B 1 163 ? 47.349  65.309 35.369  1.00 0.49 ? 163 GLN B C   1 
ATOM 4465 O O   . GLN B 1 163 ? 48.420  64.773 35.075  1.00 0.49 ? 163 GLN B O   1 
ATOM 4466 C CB  . GLN B 1 163 ? 46.069  63.712 33.823  1.00 0.49 ? 163 GLN B CB  1 
ATOM 4467 C CG  . GLN B 1 163 ? 44.763  62.919 33.562  1.00 0.49 ? 163 GLN B CG  1 
ATOM 4468 C CD  . GLN B 1 163 ? 44.892  61.968 32.370  1.00 0.49 ? 163 GLN B CD  1 
ATOM 4469 O OE1 . GLN B 1 163 ? 44.529  62.279 31.236  1.00 0.49 ? 163 GLN B OE1 1 
ATOM 4470 N NE2 . GLN B 1 163 ? 45.418  60.748 32.627  1.00 0.49 ? 163 GLN B NE2 1 
ATOM 4471 N N   . GLY B 1 164 ? 47.332  66.495 36.008  1.00 0.54 ? 164 GLY B N   1 
ATOM 4472 C CA  . GLY B 1 164 ? 48.507  67.318 36.225  1.00 0.54 ? 164 GLY B CA  1 
ATOM 4473 C C   . GLY B 1 164 ? 48.059  68.636 36.787  1.00 0.54 ? 164 GLY B C   1 
ATOM 4474 O O   . GLY B 1 164 ? 46.868  68.824 37.021  1.00 0.54 ? 164 GLY B O   1 
ATOM 4475 N N   . THR B 1 165 ? 49.022  69.557 37.033  1.00 0.52 ? 165 THR B N   1 
ATOM 4476 C CA  . THR B 1 165 ? 48.831  70.926 37.542  1.00 0.52 ? 165 THR B CA  1 
ATOM 4477 C C   . THR B 1 165 ? 47.989  70.983 38.806  1.00 0.52 ? 165 THR B C   1 
ATOM 4478 O O   . THR B 1 165 ? 46.998  71.701 38.919  1.00 0.52 ? 165 THR B O   1 
ATOM 4479 C CB  . THR B 1 165 ? 48.402  71.919 36.465  1.00 0.52 ? 165 THR B CB  1 
ATOM 4480 O OG1 . THR B 1 165 ? 49.289  71.813 35.358  1.00 0.52 ? 165 THR B OG1 1 
ATOM 4481 C CG2 . THR B 1 165 ? 48.510  73.396 36.883  1.00 0.52 ? 165 THR B CG2 1 
ATOM 4482 N N   . THR B 1 166 ? 48.361  70.167 39.813  1.00 0.56 ? 166 THR B N   1 
ATOM 4483 C CA  . THR B 1 166 ? 47.537  69.947 40.990  1.00 0.56 ? 166 THR B CA  1 
ATOM 4484 C C   . THR B 1 166 ? 47.718  71.013 42.053  1.00 0.56 ? 166 THR B C   1 
ATOM 4485 O O   . THR B 1 166 ? 48.710  71.738 42.109  1.00 0.56 ? 166 THR B O   1 
ATOM 4486 C CB  . THR B 1 166 ? 47.702  68.561 41.633  1.00 0.56 ? 166 THR B CB  1 
ATOM 4487 O OG1 . THR B 1 166 ? 48.957  68.396 42.272  1.00 0.56 ? 166 THR B OG1 1 
ATOM 4488 C CG2 . THR B 1 166 ? 47.610  67.461 40.562  1.00 0.56 ? 166 THR B CG2 1 
ATOM 4489 N N   . LEU B 1 167 ? 46.713  71.151 42.938  1.00 0.54 ? 167 LEU B N   1 
ATOM 4490 C CA  . LEU B 1 167 ? 46.804  71.935 44.152  1.00 0.54 ? 167 LEU B CA  1 
ATOM 4491 C C   . LEU B 1 167 ? 47.800  71.378 45.177  1.00 0.54 ? 167 LEU B C   1 
ATOM 4492 O O   . LEU B 1 167 ? 48.005  70.163 45.224  1.00 0.54 ? 167 LEU B O   1 
ATOM 4493 C CB  . LEU B 1 167 ? 45.407  72.034 44.800  1.00 0.54 ? 167 LEU B CB  1 
ATOM 4494 C CG  . LEU B 1 167 ? 44.431  72.918 44.007  1.00 0.54 ? 167 LEU B CG  1 
ATOM 4495 C CD1 . LEU B 1 167 ? 42.986  72.616 44.422  1.00 0.54 ? 167 LEU B CD1 1 
ATOM 4496 C CD2 . LEU B 1 167 ? 44.766  74.411 44.189  1.00 0.54 ? 167 LEU B CD2 1 
ATOM 4497 N N   . PRO B 1 168 ? 48.453  72.199 46.006  1.00 0.42 ? 168 PRO B N   1 
ATOM 4498 C CA  . PRO B 1 168 ? 49.424  71.734 46.984  1.00 0.42 ? 168 PRO B CA  1 
ATOM 4499 C C   . PRO B 1 168 ? 48.842  70.893 48.109  1.00 0.42 ? 168 PRO B C   1 
ATOM 4500 O O   . PRO B 1 168 ? 47.635  70.680 48.208  1.00 0.42 ? 168 PRO B O   1 
ATOM 4501 C CB  . PRO B 1 168 ? 50.081  73.028 47.489  1.00 0.42 ? 168 PRO B CB  1 
ATOM 4502 C CG  . PRO B 1 168 ? 48.993  74.086 47.342  1.00 0.42 ? 168 PRO B CG  1 
ATOM 4503 C CD  . PRO B 1 168 ? 48.264  73.652 46.073  1.00 0.42 ? 168 PRO B CD  1 
ATOM 4504 N N   . LYS B 1 169 ? 49.739  70.393 48.980  1.00 0.35 ? 169 LYS B N   1 
ATOM 4505 C CA  . LYS B 1 169 ? 49.544  69.285 49.903  1.00 0.35 ? 169 LYS B CA  1 
ATOM 4506 C C   . LYS B 1 169 ? 48.417  69.393 50.928  1.00 0.35 ? 169 LYS B C   1 
ATOM 4507 O O   . LYS B 1 169 ? 47.960  68.382 51.453  1.00 0.35 ? 169 LYS B O   1 
ATOM 4508 C CB  . LYS B 1 169 ? 50.889  69.030 50.633  1.00 0.35 ? 169 LYS B CB  1 
ATOM 4509 C CG  . LYS B 1 169 ? 50.998  67.676 51.360  1.00 0.35 ? 169 LYS B CG  1 
ATOM 4510 C CD  . LYS B 1 169 ? 52.338  67.479 52.091  1.00 0.35 ? 169 LYS B CD  1 
ATOM 4511 C CE  . LYS B 1 169 ? 53.548  67.400 51.153  1.00 0.35 ? 169 LYS B CE  1 
ATOM 4512 N NZ  . LYS B 1 169 ? 54.803  67.247 51.927  1.00 0.35 ? 169 LYS B NZ  1 
ATOM 4513 N N   . GLY B 1 170 ? 47.940  70.611 51.253  1.00 0.45 ? 170 GLY B N   1 
ATOM 4514 C CA  . GLY B 1 170 ? 46.804  70.781 52.154  1.00 0.45 ? 170 GLY B CA  1 
ATOM 4515 C C   . GLY B 1 170 ? 45.481  70.327 51.583  1.00 0.45 ? 170 GLY B C   1 
ATOM 4516 O O   . GLY B 1 170 ? 44.648  69.749 52.275  1.00 0.45 ? 170 GLY B O   1 
ATOM 4517 N N   . PHE B 1 171 ? 45.252  70.602 50.288  1.00 0.47 ? 171 PHE B N   1 
ATOM 4518 C CA  . PHE B 1 171 ? 43.949  70.484 49.666  1.00 0.47 ? 171 PHE B CA  1 
ATOM 4519 C C   . PHE B 1 171 ? 43.388  69.070 49.492  1.00 0.47 ? 171 PHE B C   1 
ATOM 4520 O O   . PHE B 1 171 ? 43.984  68.177 48.889  1.00 0.47 ? 171 PHE B O   1 
ATOM 4521 C CB  . PHE B 1 171 ? 43.926  71.177 48.276  1.00 0.47 ? 171 PHE B CB  1 
ATOM 4522 C CG  . PHE B 1 171 ? 44.076  72.680 48.346  1.00 0.47 ? 171 PHE B CG  1 
ATOM 4523 C CD1 . PHE B 1 171 ? 45.335  73.293 48.465  1.00 0.47 ? 171 PHE B CD1 1 
ATOM 4524 C CD2 . PHE B 1 171 ? 42.949  73.503 48.187  1.00 0.47 ? 171 PHE B CD2 1 
ATOM 4525 C CE1 . PHE B 1 171 ? 45.469  74.687 48.409  1.00 0.47 ? 171 PHE B CE1 1 
ATOM 4526 C CE2 . PHE B 1 171 ? 43.083  74.895 48.120  1.00 0.47 ? 171 PHE B CE2 1 
ATOM 4527 C CZ  . PHE B 1 171 ? 44.342  75.486 48.222  1.00 0.47 ? 171 PHE B CZ  1 
ATOM 4528 N N   . TYR B 1 172 ? 42.124  68.872 49.926  1.00 0.44 ? 172 TYR B N   1 
ATOM 4529 C CA  . TYR B 1 172 ? 41.274  67.799 49.448  1.00 0.44 ? 172 TYR B CA  1 
ATOM 4530 C C   . TYR B 1 172 ? 40.719  68.281 48.110  1.00 0.44 ? 172 TYR B C   1 
ATOM 4531 O O   . TYR B 1 172 ? 39.878  69.178 48.075  1.00 0.44 ? 172 TYR B O   1 
ATOM 4532 C CB  . TYR B 1 172 ? 40.139  67.521 50.489  1.00 0.44 ? 172 TYR B CB  1 
ATOM 4533 C CG  . TYR B 1 172 ? 39.251  66.339 50.189  1.00 0.44 ? 172 TYR B CG  1 
ATOM 4534 C CD1 . TYR B 1 172 ? 38.284  66.391 49.171  1.00 0.44 ? 172 TYR B CD1 1 
ATOM 4535 C CD2 . TYR B 1 172 ? 39.347  65.166 50.958  1.00 0.44 ? 172 TYR B CD2 1 
ATOM 4536 C CE1 . TYR B 1 172 ? 37.504  65.269 48.859  1.00 0.44 ? 172 TYR B CE1 1 
ATOM 4537 C CE2 . TYR B 1 172 ? 38.552  64.050 50.662  1.00 0.44 ? 172 TYR B CE2 1 
ATOM 4538 C CZ  . TYR B 1 172 ? 37.653  64.091 49.592  1.00 0.44 ? 172 TYR B CZ  1 
ATOM 4539 O OH  . TYR B 1 172 ? 36.871  62.957 49.296  1.00 0.44 ? 172 TYR B OH  1 
ATOM 4540 N N   . ALA B 1 173 ? 41.244  67.729 46.991  1.00 0.63 ? 173 ALA B N   1 
ATOM 4541 C CA  . ALA B 1 173 ? 40.849  67.993 45.612  1.00 0.63 ? 173 ALA B CA  1 
ATOM 4542 C C   . ALA B 1 173 ? 39.377  67.727 45.301  1.00 0.63 ? 173 ALA B C   1 
ATOM 4543 O O   . ALA B 1 173 ? 38.635  67.233 46.143  1.00 0.63 ? 173 ALA B O   1 
ATOM 4544 C CB  . ALA B 1 173 ? 41.774  67.206 44.656  1.00 0.63 ? 173 ALA B CB  1 
ATOM 4545 N N   . GLU B 1 174 ? 38.907  68.026 44.068  1.00 0.61 ? 174 GLU B N   1 
ATOM 4546 C CA  . GLU B 1 174 ? 37.502  68.080 43.701  1.00 0.61 ? 174 GLU B CA  1 
ATOM 4547 C C   . GLU B 1 174 ? 36.703  66.842 44.077  1.00 0.61 ? 174 GLU B C   1 
ATOM 4548 O O   . GLU B 1 174 ? 35.663  66.925 44.714  1.00 0.61 ? 174 GLU B O   1 
ATOM 4549 C CB  . GLU B 1 174 ? 37.330  68.391 42.188  1.00 0.61 ? 174 GLU B CB  1 
ATOM 4550 C CG  . GLU B 1 174 ? 37.833  69.794 41.769  1.00 0.61 ? 174 GLU B CG  1 
ATOM 4551 C CD  . GLU B 1 174 ? 39.339  69.844 41.503  1.00 0.61 ? 174 GLU B CD  1 
ATOM 4552 O OE1 . GLU B 1 174 ? 40.053  68.851 41.817  1.00 0.61 ? 174 GLU B OE1 1 
ATOM 4553 O OE2 . GLU B 1 174 ? 39.784  70.877 40.961  1.00 0.61 ? 174 GLU B OE2 1 
ATOM 4554 N N   . GLY B 1 175 ? 37.182  65.621 43.792  1.00 0.61 ? 175 GLY B N   1 
ATOM 4555 C CA  . GLY B 1 175 ? 36.649  64.493 44.559  1.00 0.61 ? 175 GLY B CA  1 
ATOM 4556 C C   . GLY B 1 175 ? 35.324  63.893 44.165  1.00 0.61 ? 175 GLY B C   1 
ATOM 4557 O O   . GLY B 1 175 ? 34.520  63.519 45.020  1.00 0.61 ? 175 GLY B O   1 
ATOM 4558 N N   . SER B 1 176 ? 35.091  63.722 42.845  1.00 0.55 ? 176 SER B N   1 
ATOM 4559 C CA  . SER B 1 176 ? 33.991  62.915 42.313  1.00 0.55 ? 176 SER B CA  1 
ATOM 4560 C C   . SER B 1 176 ? 33.965  61.493 42.868  1.00 0.55 ? 176 SER B C   1 
ATOM 4561 O O   . SER B 1 176 ? 34.994  60.819 42.953  1.00 0.55 ? 176 SER B O   1 
ATOM 4562 C CB  . SER B 1 176 ? 33.996  62.838 40.759  1.00 0.55 ? 176 SER B CB  1 
ATOM 4563 O OG  . SER B 1 176 ? 32.872  62.110 40.256  1.00 0.55 ? 176 SER B OG  1 
ATOM 4564 N N   . ARG B 1 177 ? 32.764  61.032 43.273  1.00 0.46 ? 177 ARG B N   1 
ATOM 4565 C CA  . ARG B 1 177 ? 32.532  59.760 43.916  1.00 0.46 ? 177 ARG B CA  1 
ATOM 4566 C C   . ARG B 1 177 ? 31.140  59.310 43.534  1.00 0.46 ? 177 ARG B C   1 
ATOM 4567 O O   . ARG B 1 177 ? 30.230  60.131 43.420  1.00 0.46 ? 177 ARG B O   1 
ATOM 4568 C CB  . ARG B 1 177 ? 32.556  59.864 45.465  1.00 0.46 ? 177 ARG B CB  1 
ATOM 4569 C CG  . ARG B 1 177 ? 33.967  60.036 46.062  1.00 0.46 ? 177 ARG B CG  1 
ATOM 4570 C CD  . ARG B 1 177 ? 33.993  60.239 47.578  1.00 0.46 ? 177 ARG B CD  1 
ATOM 4571 N NE  . ARG B 1 177 ? 33.471  61.619 47.841  1.00 0.46 ? 177 ARG B NE  1 
ATOM 4572 C CZ  . ARG B 1 177 ? 32.424  61.919 48.618  1.00 0.46 ? 177 ARG B CZ  1 
ATOM 4573 N NH1 . ARG B 1 177 ? 31.957  63.168 48.610  1.00 0.46 ? 177 ARG B NH1 1 
ATOM 4574 N NH2 . ARG B 1 177 ? 31.837  61.013 49.393  1.00 0.46 ? 177 ARG B NH2 1 
ATOM 4575 N N   . GLY B 1 178 ? 30.941  57.981 43.382  1.00 0.35 ? 178 GLY B N   1 
ATOM 4576 C CA  . GLY B 1 178 ? 29.749  57.373 42.784  1.00 0.35 ? 178 GLY B CA  1 
ATOM 4577 C C   . GLY B 1 178 ? 28.392  57.705 43.350  1.00 0.35 ? 178 GLY B C   1 
ATOM 4578 O O   . GLY B 1 178 ? 27.403  57.705 42.629  1.00 0.35 ? 178 GLY B O   1 
ATOM 4579 N N   . GLY B 1 179 ? 28.313  57.968 44.667  1.00 0.39 ? 179 GLY B N   1 
ATOM 4580 C CA  . GLY B 1 179 ? 27.067  58.340 45.331  1.00 0.39 ? 179 GLY B CA  1 
ATOM 4581 C C   . GLY B 1 179 ? 26.921  59.809 45.586  1.00 0.39 ? 179 GLY B C   1 
ATOM 4582 O O   . GLY B 1 179 ? 25.895  60.253 46.086  1.00 0.39 ? 179 GLY B O   1 
ATOM 4583 N N   . SER B 1 180 ? 27.949  60.618 45.262  1.00 0.40 ? 180 SER B N   1 
ATOM 4584 C CA  . SER B 1 180 ? 27.825  62.069 45.293  1.00 0.40 ? 180 SER B CA  1 
ATOM 4585 C C   . SER B 1 180 ? 27.181  62.529 43.997  1.00 0.40 ? 180 SER B C   1 
ATOM 4586 O O   . SER B 1 180 ? 26.188  63.247 44.003  1.00 0.40 ? 180 SER B O   1 
ATOM 4587 C CB  . SER B 1 180 ? 29.206  62.754 45.514  1.00 0.40 ? 180 SER B CB  1 
ATOM 4588 O OG  . SER B 1 180 ? 29.123  64.174 45.672  1.00 0.40 ? 180 SER B OG  1 
ATOM 4589 N N   . GLN B 1 181 ? 27.681  62.064 42.834  1.00 0.50 ? 181 GLN B N   1 
ATOM 4590 C CA  . GLN B 1 181 ? 27.026  62.336 41.573  1.00 0.50 ? 181 GLN B CA  1 
ATOM 4591 C C   . GLN B 1 181 ? 27.412  61.266 40.574  1.00 0.50 ? 181 GLN B C   1 
ATOM 4592 O O   . GLN B 1 181 ? 28.534  60.767 40.585  1.00 0.50 ? 181 GLN B O   1 
ATOM 4593 C CB  . GLN B 1 181 ? 27.390  63.733 40.998  1.00 0.50 ? 181 GLN B CB  1 
ATOM 4594 C CG  . GLN B 1 181 ? 28.887  64.075 41.204  1.00 0.50 ? 181 GLN B CG  1 
ATOM 4595 C CD  . GLN B 1 181 ? 29.434  65.315 40.484  1.00 0.50 ? 181 GLN B CD  1 
ATOM 4596 O OE1 . GLN B 1 181 ? 30.653  65.496 40.461  1.00 0.50 ? 181 GLN B OE1 1 
ATOM 4597 N NE2 . GLN B 1 181 ? 28.579  66.182 39.911  1.00 0.50 ? 181 GLN B NE2 1 
ATOM 4598 N N   . ALA B 1 182 ? 26.476  60.901 39.671  1.00 0.51 ? 182 ALA B N   1 
ATOM 4599 C CA  . ALA B 1 182 ? 26.670  59.779 38.774  1.00 0.51 ? 182 ALA B CA  1 
ATOM 4600 C C   . ALA B 1 182 ? 26.377  60.063 37.302  1.00 0.51 ? 182 ALA B C   1 
ATOM 4601 O O   . ALA B 1 182 ? 26.730  59.277 36.429  1.00 0.51 ? 182 ALA B O   1 
ATOM 4602 C CB  . ALA B 1 182 ? 25.707  58.671 39.227  1.00 0.51 ? 182 ALA B CB  1 
ATOM 4603 N N   . SER B 1 183 ? 25.703  61.181 36.966  1.00 0.55 ? 183 SER B N   1 
ATOM 4604 C CA  . SER B 1 183 ? 25.137  61.362 35.631  1.00 0.55 ? 183 SER B CA  1 
ATOM 4605 C C   . SER B 1 183 ? 26.095  61.814 34.546  1.00 0.55 ? 183 SER B C   1 
ATOM 4606 O O   . SER B 1 183 ? 25.806  61.710 33.357  1.00 0.55 ? 183 SER B O   1 
ATOM 4607 C CB  . SER B 1 183 ? 23.999  62.403 35.653  1.00 0.55 ? 183 SER B CB  1 
ATOM 4608 O OG  . SER B 1 183 ? 23.152  62.177 36.781  1.00 0.55 ? 183 SER B OG  1 
ATOM 4609 N N   . SER B 1 184 ? 27.254  62.359 34.939  1.00 0.61 ? 184 SER B N   1 
ATOM 4610 C CA  . SER B 1 184 ? 28.345  62.700 34.039  1.00 0.61 ? 184 SER B CA  1 
ATOM 4611 C C   . SER B 1 184 ? 29.168  61.478 33.672  1.00 0.61 ? 184 SER B C   1 
ATOM 4612 O O   . SER B 1 184 ? 29.335  60.550 34.458  1.00 0.61 ? 184 SER B O   1 
ATOM 4613 C CB  . SER B 1 184 ? 29.301  63.715 34.704  1.00 0.61 ? 184 SER B CB  1 
ATOM 4614 O OG  . SER B 1 184 ? 30.232  64.311 33.798  1.00 0.61 ? 184 SER B OG  1 
ATOM 4615 N N   . ARG B 1 185 ? 29.747  61.455 32.458  1.00 0.58 ? 185 ARG B N   1 
ATOM 4616 C CA  . ARG B 1 185 ? 30.786  60.506 32.107  1.00 0.58 ? 185 ARG B CA  1 
ATOM 4617 C C   . ARG B 1 185 ? 32.075  60.766 32.873  1.00 0.58 ? 185 ARG B C   1 
ATOM 4618 O O   . ARG B 1 185 ? 32.405  61.890 33.241  1.00 0.58 ? 185 ARG B O   1 
ATOM 4619 C CB  . ARG B 1 185 ? 31.117  60.523 30.591  1.00 0.58 ? 185 ARG B CB  1 
ATOM 4620 C CG  . ARG B 1 185 ? 29.918  60.172 29.684  1.00 0.58 ? 185 ARG B CG  1 
ATOM 4621 C CD  . ARG B 1 185 ? 30.213  60.192 28.176  1.00 0.58 ? 185 ARG B CD  1 
ATOM 4622 N NE  . ARG B 1 185 ? 31.055  58.991 27.861  1.00 0.58 ? 185 ARG B NE  1 
ATOM 4623 C CZ  . ARG B 1 185 ? 31.318  58.557 26.621  1.00 0.58 ? 185 ARG B CZ  1 
ATOM 4624 N NH1 . ARG B 1 185 ? 31.939  57.390 26.442  1.00 0.58 ? 185 ARG B NH1 1 
ATOM 4625 N NH2 . ARG B 1 185 ? 30.934  59.243 25.551  1.00 0.58 ? 185 ARG B NH2 1 
ATOM 4626 N N   . SER B 1 186 ? 32.887  59.716 33.096  1.00 0.63 ? 186 SER B N   1 
ATOM 4627 C CA  . SER B 1 186 ? 34.120  59.821 33.862  1.00 0.63 ? 186 SER B CA  1 
ATOM 4628 C C   . SER B 1 186 ? 35.242  60.587 33.162  1.00 0.63 ? 186 SER B C   1 
ATOM 4629 O O   . SER B 1 186 ? 36.168  61.076 33.804  1.00 0.63 ? 186 SER B O   1 
ATOM 4630 C CB  . SER B 1 186 ? 34.634  58.404 34.221  1.00 0.63 ? 186 SER B CB  1 
ATOM 4631 O OG  . SER B 1 186 ? 34.777  57.580 33.058  1.00 0.63 ? 186 SER B OG  1 
ATOM 4632 N N   . SER B 1 187 ? 35.165  60.704 31.820  1.00 0.64 ? 187 SER B N   1 
ATOM 4633 C CA  . SER B 1 187 ? 36.033  61.513 30.970  1.00 0.64 ? 187 SER B CA  1 
ATOM 4634 C C   . SER B 1 187 ? 37.429  60.919 30.763  1.00 0.64 ? 187 SER B C   1 
ATOM 4635 O O   . SER B 1 187 ? 38.308  61.527 30.164  1.00 0.64 ? 187 SER B O   1 
ATOM 4636 C CB  . SER B 1 187 ? 35.970  63.032 31.330  1.00 0.64 ? 187 SER B CB  1 
ATOM 4637 O OG  . SER B 1 187 ? 36.420  63.924 30.305  1.00 0.64 ? 187 SER B OG  1 
ATOM 4638 N N   . SER B 1 188 ? 37.625  59.623 31.115  1.00 0.64 ? 188 SER B N   1 
ATOM 4639 C CA  . SER B 1 188 ? 38.858  58.861 30.875  1.00 0.64 ? 188 SER B CA  1 
ATOM 4640 C C   . SER B 1 188 ? 39.056  58.451 29.423  1.00 0.64 ? 188 SER B C   1 
ATOM 4641 O O   . SER B 1 188 ? 40.101  57.945 29.016  1.00 0.64 ? 188 SER B O   1 
ATOM 4642 C CB  . SER B 1 188 ? 38.904  57.575 31.737  1.00 0.64 ? 188 SER B CB  1 
ATOM 4643 O OG  . SER B 1 188 ? 37.805  56.692 31.486  1.00 0.64 ? 188 SER B OG  1 
ATOM 4644 N N   . ARG B 1 189 ? 38.005  58.685 28.620  1.00 0.59 ? 189 ARG B N   1 
ATOM 4645 C CA  . ARG B 1 189 ? 37.890  58.537 27.186  1.00 0.59 ? 189 ARG B CA  1 
ATOM 4646 C C   . ARG B 1 189 ? 38.896  59.335 26.381  1.00 0.59 ? 189 ARG B C   1 
ATOM 4647 O O   . ARG B 1 189 ? 39.302  58.894 25.307  1.00 0.59 ? 189 ARG B O   1 
ATOM 4648 C CB  . ARG B 1 189 ? 36.471  59.043 26.791  1.00 0.59 ? 189 ARG B CB  1 
ATOM 4649 C CG  . ARG B 1 189 ? 36.115  59.028 25.284  1.00 0.59 ? 189 ARG B CG  1 
ATOM 4650 C CD  . ARG B 1 189 ? 34.731  59.608 24.947  1.00 0.59 ? 189 ARG B CD  1 
ATOM 4651 N NE  . ARG B 1 189 ? 34.724  61.088 25.256  1.00 0.59 ? 189 ARG B NE  1 
ATOM 4652 C CZ  . ARG B 1 189 ? 34.949  62.077 24.375  1.00 0.59 ? 189 ARG B CZ  1 
ATOM 4653 N NH1 . ARG B 1 189 ? 34.989  63.343 24.794  1.00 0.59 ? 189 ARG B NH1 1 
ATOM 4654 N NH2 . ARG B 1 189 ? 35.143  61.827 23.087  1.00 0.59 ? 189 ARG B NH2 1 
ATOM 4655 N N   . SER B 1 190 ? 39.264  60.539 26.853  1.00 0.58 ? 190 SER B N   1 
ATOM 4656 C CA  . SER B 1 190 ? 40.153  61.404 26.109  1.00 0.58 ? 190 SER B CA  1 
ATOM 4657 C C   . SER B 1 190 ? 41.139  62.011 27.071  1.00 0.58 ? 190 SER B C   1 
ATOM 4658 O O   . SER B 1 190 ? 40.785  62.896 27.845  1.00 0.58 ? 190 SER B O   1 
ATOM 4659 C CB  . SER B 1 190 ? 39.398  62.569 25.418  1.00 0.58 ? 190 SER B CB  1 
ATOM 4660 O OG  . SER B 1 190 ? 38.431  62.093 24.475  1.00 0.58 ? 190 SER B OG  1 
ATOM 4661 N N   . ARG B 1 191 ? 42.403  61.543 27.054  1.00 0.59 ? 191 ARG B N   1 
ATOM 4662 C CA  . ARG B 1 191 ? 43.443  62.012 27.956  1.00 0.59 ? 191 ARG B CA  1 
ATOM 4663 C C   . ARG B 1 191 ? 43.811  63.494 27.889  1.00 0.59 ? 191 ARG B C   1 
ATOM 4664 O O   . ARG B 1 191 ? 43.880  64.108 26.825  1.00 0.59 ? 191 ARG B O   1 
ATOM 4665 C CB  . ARG B 1 191 ? 44.736  61.163 27.826  1.00 0.59 ? 191 ARG B CB  1 
ATOM 4666 C CG  . ARG B 1 191 ? 45.437  61.209 26.449  1.00 0.59 ? 191 ARG B CG  1 
ATOM 4667 C CD  . ARG B 1 191 ? 46.724  60.375 26.424  1.00 0.59 ? 191 ARG B CD  1 
ATOM 4668 N NE  . ARG B 1 191 ? 47.221  60.308 25.004  1.00 0.59 ? 191 ARG B NE  1 
ATOM 4669 C CZ  . ARG B 1 191 ? 46.957  59.309 24.151  1.00 0.59 ? 191 ARG B CZ  1 
ATOM 4670 N NH1 . ARG B 1 191 ? 47.423  59.369 22.903  1.00 0.59 ? 191 ARG B NH1 1 
ATOM 4671 N NH2 . ARG B 1 191 ? 46.239  58.249 24.496  1.00 0.59 ? 191 ARG B NH2 1 
ATOM 4672 N N   . ASN B 1 192 ? 44.091  64.098 29.062  1.00 0.61 ? 192 ASN B N   1 
ATOM 4673 C CA  . ASN B 1 192 ? 44.548  65.469 29.169  1.00 0.61 ? 192 ASN B CA  1 
ATOM 4674 C C   . ASN B 1 192 ? 46.028  65.607 28.825  1.00 0.61 ? 192 ASN B C   1 
ATOM 4675 O O   . ASN B 1 192 ? 46.817  64.671 28.937  1.00 0.61 ? 192 ASN B O   1 
ATOM 4676 C CB  . ASN B 1 192 ? 44.334  66.031 30.595  1.00 0.61 ? 192 ASN B CB  1 
ATOM 4677 C CG  . ASN B 1 192 ? 42.861  66.079 30.977  1.00 0.61 ? 192 ASN B CG  1 
ATOM 4678 O OD1 . ASN B 1 192 ? 42.367  65.273 31.764  1.00 0.61 ? 192 ASN B OD1 1 
ATOM 4679 N ND2 . ASN B 1 192 ? 42.132  67.094 30.460  1.00 0.61 ? 192 ASN B ND2 1 
ATOM 4680 N N   . SER B 1 193 ? 46.451  66.812 28.391  1.00 0.57 ? 193 SER B N   1 
ATOM 4681 C CA  . SER B 1 193 ? 47.850  67.119 28.123  1.00 0.57 ? 193 SER B CA  1 
ATOM 4682 C C   . SER B 1 193 ? 48.720  67.134 29.372  1.00 0.57 ? 193 SER B C   1 
ATOM 4683 O O   . SER B 1 193 ? 48.716  68.102 30.132  1.00 0.57 ? 193 SER B O   1 
ATOM 4684 C CB  . SER B 1 193 ? 48.011  68.493 27.422  1.00 0.57 ? 193 SER B CB  1 
ATOM 4685 O OG  . SER B 1 193 ? 47.217  68.527 26.234  1.00 0.57 ? 193 SER B OG  1 
ATOM 4686 N N   . SER B 1 194 ? 49.509  66.071 29.617  1.00 0.62 ? 194 SER B N   1 
ATOM 4687 C CA  . SER B 1 194 ? 50.332  65.956 30.811  1.00 0.62 ? 194 SER B CA  1 
ATOM 4688 C C   . SER B 1 194 ? 51.511  65.062 30.509  1.00 0.62 ? 194 SER B C   1 
ATOM 4689 O O   . SER B 1 194 ? 51.441  64.208 29.629  1.00 0.62 ? 194 SER B O   1 
ATOM 4690 C CB  . SER B 1 194 ? 49.544  65.361 32.013  1.00 0.62 ? 194 SER B CB  1 
ATOM 4691 O OG  . SER B 1 194 ? 50.335  65.168 33.197  1.00 0.62 ? 194 SER B OG  1 
ATOM 4692 N N   . ARG B 1 195 ? 52.628  65.261 31.239  1.00 0.61 ? 195 ARG B N   1 
ATOM 4693 C CA  . ARG B 1 195 ? 53.833  64.465 31.139  1.00 0.61 ? 195 ARG B CA  1 
ATOM 4694 C C   . ARG B 1 195 ? 54.134  63.707 32.422  1.00 0.61 ? 195 ARG B C   1 
ATOM 4695 O O   . ARG B 1 195 ? 55.238  63.194 32.581  1.00 0.61 ? 195 ARG B O   1 
ATOM 4696 C CB  . ARG B 1 195 ? 55.061  65.379 30.859  1.00 0.61 ? 195 ARG B CB  1 
ATOM 4697 C CG  . ARG B 1 195 ? 55.420  66.411 31.961  1.00 0.61 ? 195 ARG B CG  1 
ATOM 4698 C CD  . ARG B 1 195 ? 56.631  67.273 31.580  1.00 0.61 ? 195 ARG B CD  1 
ATOM 4699 N NE  . ARG B 1 195 ? 56.859  68.302 32.660  1.00 0.61 ? 195 ARG B NE  1 
ATOM 4700 C CZ  . ARG B 1 195 ? 57.723  68.177 33.679  1.00 0.61 ? 195 ARG B CZ  1 
ATOM 4701 N NH1 . ARG B 1 195 ? 57.903  69.205 34.510  1.00 0.61 ? 195 ARG B NH1 1 
ATOM 4702 N NH2 . ARG B 1 195 ? 58.410  67.059 33.883  1.00 0.61 ? 195 ARG B NH2 1 
ATOM 4703 N N   . ASN B 1 196 ? 53.202  63.675 33.403  1.00 0.71 ? 196 ASN B N   1 
ATOM 4704 C CA  . ASN B 1 196 ? 53.549  63.267 34.755  1.00 0.71 ? 196 ASN B CA  1 
ATOM 4705 C C   . ASN B 1 196 ? 53.088  61.872 35.150  1.00 0.71 ? 196 ASN B C   1 
ATOM 4706 O O   . ASN B 1 196 ? 53.283  61.458 36.289  1.00 0.71 ? 196 ASN B O   1 
ATOM 4707 C CB  . ASN B 1 196 ? 52.970  64.320 35.736  1.00 0.71 ? 196 ASN B CB  1 
ATOM 4708 C CG  . ASN B 1 196 ? 53.765  64.365 37.033  1.00 0.71 ? 196 ASN B CG  1 
ATOM 4709 O OD1 . ASN B 1 196 ? 54.992  64.280 37.012  1.00 0.71 ? 196 ASN B OD1 1 
ATOM 4710 N ND2 . ASN B 1 196 ? 53.084  64.592 38.176  1.00 0.71 ? 196 ASN B ND2 1 
ATOM 4711 N N   . SER B 1 197 ? 52.457  61.107 34.240  1.00 0.72 ? 197 SER B N   1 
ATOM 4712 C CA  . SER B 1 197 ? 52.288  59.664 34.412  1.00 0.72 ? 197 SER B CA  1 
ATOM 4713 C C   . SER B 1 197 ? 51.430  59.206 35.592  1.00 0.72 ? 197 SER B C   1 
ATOM 4714 O O   . SER B 1 197 ? 51.640  58.131 36.150  1.00 0.72 ? 197 SER B O   1 
ATOM 4715 C CB  . SER B 1 197 ? 53.644  58.918 34.543  1.00 0.72 ? 197 SER B CB  1 
ATOM 4716 O OG  . SER B 1 197 ? 54.714  59.491 33.792  1.00 0.72 ? 197 SER B OG  1 
ATOM 4717 N N   . THR B 1 198 ? 50.441  60.025 36.018  1.00 0.77 ? 198 THR B N   1 
ATOM 4718 C CA  . THR B 1 198 ? 49.502  59.748 37.124  1.00 0.77 ? 198 THR B CA  1 
ATOM 4719 C C   . THR B 1 198 ? 50.101  59.180 38.431  1.00 0.77 ? 198 THR B C   1 
ATOM 4720 O O   . THR B 1 198 ? 49.786  58.052 38.827  1.00 0.77 ? 198 THR B O   1 
ATOM 4721 C CB  . THR B 1 198 ? 48.233  58.998 36.696  1.00 0.77 ? 198 THR B CB  1 
ATOM 4722 O OG1 . THR B 1 198 ? 48.510  57.891 35.851  1.00 0.77 ? 198 THR B OG1 1 
ATOM 4723 C CG2 . THR B 1 198 ? 47.347  59.954 35.872  1.00 0.77 ? 198 THR B CG2 1 
ATOM 4724 N N   . PRO B 1 199 ? 50.992  59.895 39.145  1.00 0.75 ? 199 PRO B N   1 
ATOM 4725 C CA  . PRO B 1 199 ? 51.611  59.429 40.389  1.00 0.75 ? 199 PRO B CA  1 
ATOM 4726 C C   . PRO B 1 199 ? 50.669  59.135 41.548  1.00 0.75 ? 199 PRO B C   1 
ATOM 4727 O O   . PRO B 1 199 ? 49.514  59.554 41.536  1.00 0.75 ? 199 PRO B O   1 
ATOM 4728 C CB  . PRO B 1 199 ? 52.589  60.553 40.783  1.00 0.75 ? 199 PRO B CB  1 
ATOM 4729 C CG  . PRO B 1 199 ? 52.738  61.405 39.530  1.00 0.75 ? 199 PRO B CG  1 
ATOM 4730 C CD  . PRO B 1 199 ? 51.364  61.285 38.888  1.00 0.75 ? 199 PRO B CD  1 
ATOM 4731 N N   . GLY B 1 200 ? 51.169  58.409 42.576  1.00 0.75 ? 200 GLY B N   1 
ATOM 4732 C CA  . GLY B 1 200 ? 50.448  58.139 43.819  1.00 0.75 ? 200 GLY B CA  1 
ATOM 4733 C C   . GLY B 1 200 ? 50.724  59.132 44.919  1.00 0.75 ? 200 GLY B C   1 
ATOM 4734 O O   . GLY B 1 200 ? 51.010  60.297 44.686  1.00 0.75 ? 200 GLY B O   1 
ATOM 4735 N N   . SER B 1 201 ? 50.664  58.674 46.184  1.00 0.21 ? 201 SER B N   1 
ATOM 4736 C CA  . SER B 1 201 ? 50.921  59.515 47.340  1.00 0.21 ? 201 SER B CA  1 
ATOM 4737 C C   . SER B 1 201 ? 51.535  58.645 48.416  1.00 0.21 ? 201 SER B C   1 
ATOM 4738 O O   . SER B 1 201 ? 51.225  57.459 48.513  1.00 0.21 ? 201 SER B O   1 
ATOM 4739 C CB  . SER B 1 201 ? 49.624  60.181 47.882  1.00 0.21 ? 201 SER B CB  1 
ATOM 4740 O OG  . SER B 1 201 ? 49.809  60.813 49.162  1.00 0.21 ? 201 SER B OG  1 
ATOM 4741 N N   . SER B 1 202 ? 52.437  59.229 49.237  1.00 0.30 ? 202 SER B N   1 
ATOM 4742 C CA  . SER B 1 202 ? 53.266  58.529 50.218  1.00 0.30 ? 202 SER B CA  1 
ATOM 4743 C C   . SER B 1 202 ? 52.522  58.020 51.448  1.00 0.30 ? 202 SER B C   1 
ATOM 4744 O O   . SER B 1 202 ? 52.934  57.053 52.082  1.00 0.30 ? 202 SER B O   1 
ATOM 4745 C CB  . SER B 1 202 ? 54.463  59.418 50.655  1.00 0.30 ? 202 SER B CB  1 
ATOM 4746 O OG  . SER B 1 202 ? 55.473  58.665 51.328  1.00 0.30 ? 202 SER B OG  1 
ATOM 4747 N N   . ARG B 1 203 ? 51.371  58.631 51.808  1.00 0.34 ? 203 ARG B N   1 
ATOM 4748 C CA  . ARG B 1 203 ? 50.579  58.189 52.950  1.00 0.34 ? 203 ARG B CA  1 
ATOM 4749 C C   . ARG B 1 203 ? 49.986  56.794 52.768  1.00 0.34 ? 203 ARG B C   1 
ATOM 4750 O O   . ARG B 1 203 ? 50.021  55.957 53.664  1.00 0.34 ? 203 ARG B O   1 
ATOM 4751 C CB  . ARG B 1 203 ? 49.454  59.201 53.287  1.00 0.34 ? 203 ARG B CB  1 
ATOM 4752 C CG  . ARG B 1 203 ? 49.975  60.577 53.747  1.00 0.34 ? 203 ARG B CG  1 
ATOM 4753 C CD  . ARG B 1 203 ? 48.873  61.434 54.383  1.00 0.34 ? 203 ARG B CD  1 
ATOM 4754 N NE  . ARG B 1 203 ? 49.495  62.752 54.734  1.00 0.34 ? 203 ARG B NE  1 
ATOM 4755 C CZ  . ARG B 1 203 ? 49.056  63.539 55.726  1.00 0.34 ? 203 ARG B CZ  1 
ATOM 4756 N NH1 . ARG B 1 203 ? 49.616  64.737 55.899  1.00 0.34 ? 203 ARG B NH1 1 
ATOM 4757 N NH2 . ARG B 1 203 ? 48.087  63.189 56.555  1.00 0.34 ? 203 ARG B NH2 1 
ATOM 4758 N N   . GLY B 1 204 ? 49.442  56.504 51.569  1.00 0.35 ? 204 GLY B N   1 
ATOM 4759 C CA  . GLY B 1 204 ? 49.099  55.144 51.167  1.00 0.35 ? 204 GLY B CA  1 
ATOM 4760 C C   . GLY B 1 204 ? 47.853  54.498 51.722  1.00 0.35 ? 204 GLY B C   1 
ATOM 4761 O O   . GLY B 1 204 ? 47.583  53.354 51.367  1.00 0.35 ? 204 GLY B O   1 
ATOM 4762 N N   . THR B 1 205 ? 47.080  55.201 52.572  1.00 0.44 ? 205 THR B N   1 
ATOM 4763 C CA  . THR B 1 205 ? 45.895  54.682 53.253  1.00 0.44 ? 205 THR B CA  1 
ATOM 4764 C C   . THR B 1 205 ? 45.016  55.875 53.585  1.00 0.44 ? 205 THR B C   1 
ATOM 4765 O O   . THR B 1 205 ? 45.527  56.976 53.768  1.00 0.44 ? 205 THR B O   1 
ATOM 4766 C CB  . THR B 1 205 ? 46.245  53.922 54.542  1.00 0.44 ? 205 THR B CB  1 
ATOM 4767 O OG1 . THR B 1 205 ? 46.726  52.624 54.239  1.00 0.44 ? 205 THR B OG1 1 
ATOM 4768 C CG2 . THR B 1 205 ? 45.070  53.664 55.502  1.00 0.44 ? 205 THR B CG2 1 
ATOM 4769 N N   . SER B 1 206 ? 43.672  55.688 53.668  1.00 0.44 ? 206 SER B N   1 
ATOM 4770 C CA  . SER B 1 206 ? 42.708  56.743 53.962  1.00 0.44 ? 206 SER B CA  1 
ATOM 4771 C C   . SER B 1 206 ? 41.531  56.151 54.729  1.00 0.44 ? 206 SER B C   1 
ATOM 4772 O O   . SER B 1 206 ? 41.284  54.958 54.549  1.00 0.44 ? 206 SER B O   1 
ATOM 4773 C CB  . SER B 1 206 ? 42.060  57.332 52.688  1.00 0.44 ? 206 SER B CB  1 
ATOM 4774 O OG  . SER B 1 206 ? 43.028  57.862 51.787  1.00 0.44 ? 206 SER B OG  1 
ATOM 4775 N N   . PRO B 1 207 ? 40.756  56.870 55.561  1.00 0.40 ? 207 PRO B N   1 
ATOM 4776 C CA  . PRO B 1 207 ? 39.711  56.276 56.400  1.00 0.40 ? 207 PRO B CA  1 
ATOM 4777 C C   . PRO B 1 207 ? 38.464  55.880 55.631  1.00 0.40 ? 207 PRO B C   1 
ATOM 4778 O O   . PRO B 1 207 ? 37.888  54.834 55.919  1.00 0.40 ? 207 PRO B O   1 
ATOM 4779 C CB  . PRO B 1 207 ? 39.384  57.375 57.435  1.00 0.40 ? 207 PRO B CB  1 
ATOM 4780 C CG  . PRO B 1 207 ? 39.798  58.685 56.761  1.00 0.40 ? 207 PRO B CG  1 
ATOM 4781 C CD  . PRO B 1 207 ? 41.002  58.268 55.916  1.00 0.40 ? 207 PRO B CD  1 
ATOM 4782 N N   . ALA B 1 208 ? 37.996  56.708 54.684  1.00 0.45 ? 208 ALA B N   1 
ATOM 4783 C CA  . ALA B 1 208 ? 36.764  56.449 53.985  1.00 0.45 ? 208 ALA B CA  1 
ATOM 4784 C C   . ALA B 1 208 ? 36.703  57.278 52.718  1.00 0.45 ? 208 ALA B C   1 
ATOM 4785 O O   . ALA B 1 208 ? 37.413  58.269 52.565  1.00 0.45 ? 208 ALA B O   1 
ATOM 4786 C CB  . ALA B 1 208 ? 35.547  56.808 54.868  1.00 0.45 ? 208 ALA B CB  1 
ATOM 4787 N N   . ARG B 1 209 ? 35.814  56.905 51.776  1.00 0.38 ? 209 ARG B N   1 
ATOM 4788 C CA  . ARG B 1 209 ? 35.487  57.709 50.609  1.00 0.38 ? 209 ARG B CA  1 
ATOM 4789 C C   . ARG B 1 209 ? 34.522  58.853 50.947  1.00 0.38 ? 209 ARG B C   1 
ATOM 4790 O O   . ARG B 1 209 ? 33.393  58.928 50.457  1.00 0.38 ? 209 ARG B O   1 
ATOM 4791 C CB  . ARG B 1 209 ? 34.925  56.813 49.475  1.00 0.38 ? 209 ARG B CB  1 
ATOM 4792 C CG  . ARG B 1 209 ? 36.030  56.001 48.766  1.00 0.38 ? 209 ARG B CG  1 
ATOM 4793 C CD  . ARG B 1 209 ? 35.533  55.104 47.626  1.00 0.38 ? 209 ARG B CD  1 
ATOM 4794 N NE  . ARG B 1 209 ? 36.744  54.631 46.878  1.00 0.38 ? 209 ARG B NE  1 
ATOM 4795 C CZ  . ARG B 1 209 ? 37.300  53.415 46.891  1.00 0.38 ? 209 ARG B CZ  1 
ATOM 4796 N NH1 . ARG B 1 209 ? 38.394  53.194 46.167  1.00 0.38 ? 209 ARG B NH1 1 
ATOM 4797 N NH2 . ARG B 1 209 ? 36.772  52.423 47.598  1.00 0.38 ? 209 ARG B NH2 1 
ATOM 4798 N N   . MET B 1 210 ? 34.981  59.793 51.790  1.00 0.33 ? 210 MET B N   1 
ATOM 4799 C CA  . MET B 1 210 ? 34.219  60.891 52.347  1.00 0.33 ? 210 MET B CA  1 
ATOM 4800 C C   . MET B 1 210 ? 34.921  62.200 52.030  1.00 0.33 ? 210 MET B C   1 
ATOM 4801 O O   . MET B 1 210 ? 36.142  62.248 51.898  1.00 0.33 ? 210 MET B O   1 
ATOM 4802 C CB  . MET B 1 210 ? 34.098  60.704 53.882  1.00 0.33 ? 210 MET B CB  1 
ATOM 4803 C CG  . MET B 1 210 ? 33.443  61.854 54.678  1.00 0.33 ? 210 MET B CG  1 
ATOM 4804 S SD  . MET B 1 210 ? 31.768  62.299 54.118  1.00 0.33 ? 210 MET B SD  1 
ATOM 4805 C CE  . MET B 1 210 ? 31.565  63.640 55.324  1.00 0.33 ? 210 MET B CE  1 
ATOM 4806 N N   . ALA B 1 211 ? 34.145  63.294 51.863  1.00 0.43 ? 211 ALA B N   1 
ATOM 4807 C CA  . ALA B 1 211 ? 34.651  64.642 51.698  1.00 0.43 ? 211 ALA B CA  1 
ATOM 4808 C C   . ALA B 1 211 ? 35.164  65.199 53.019  1.00 0.43 ? 211 ALA B C   1 
ATOM 4809 O O   . ALA B 1 211 ? 34.385  65.440 53.941  1.00 0.43 ? 211 ALA B O   1 
ATOM 4810 C CB  . ALA B 1 211 ? 33.528  65.563 51.168  1.00 0.43 ? 211 ALA B CB  1 
ATOM 4811 N N   . GLY B 1 212 ? 36.490  65.434 53.133  1.00 0.47 ? 212 GLY B N   1 
ATOM 4812 C CA  . GLY B 1 212 ? 37.137  65.808 54.390  1.00 0.47 ? 212 GLY B CA  1 
ATOM 4813 C C   . GLY B 1 212 ? 36.999  64.782 55.486  1.00 0.47 ? 212 GLY B C   1 
ATOM 4814 O O   . GLY B 1 212 ? 37.175  63.592 55.252  1.00 0.47 ? 212 GLY B O   1 
ATOM 4815 N N   . ASN B 1 213 ? 36.735  65.243 56.727  1.00 0.42 ? 213 ASN B N   1 
ATOM 4816 C CA  . ASN B 1 213 ? 36.572  64.399 57.903  1.00 0.42 ? 213 ASN B CA  1 
ATOM 4817 C C   . ASN B 1 213 ? 37.841  63.627 58.294  1.00 0.42 ? 213 ASN B C   1 
ATOM 4818 O O   . ASN B 1 213 ? 37.788  62.506 58.801  1.00 0.42 ? 213 ASN B O   1 
ATOM 4819 C CB  . ASN B 1 213 ? 35.319  63.490 57.735  1.00 0.42 ? 213 ASN B CB  1 
ATOM 4820 C CG  . ASN B 1 213 ? 34.776  62.973 59.060  1.00 0.42 ? 213 ASN B CG  1 
ATOM 4821 O OD1 . ASN B 1 213 ? 34.679  63.705 60.045  1.00 0.42 ? 213 ASN B OD1 1 
ATOM 4822 N ND2 . ASN B 1 213 ? 34.338  61.693 59.090  1.00 0.42 ? 213 ASN B ND2 1 
ATOM 4823 N N   . GLY B 1 214 ? 39.017  64.244 58.071  1.00 0.45 ? 214 GLY B N   1 
ATOM 4824 C CA  . GLY B 1 214 ? 40.307  63.711 58.467  1.00 0.45 ? 214 GLY B CA  1 
ATOM 4825 C C   . GLY B 1 214 ? 41.337  64.022 57.422  1.00 0.45 ? 214 GLY B C   1 
ATOM 4826 O O   . GLY B 1 214 ? 41.085  63.911 56.222  1.00 0.45 ? 214 GLY B O   1 
ATOM 4827 N N   . GLY B 1 215 ? 42.556  64.402 57.844  1.00 0.46 ? 215 GLY B N   1 
ATOM 4828 C CA  . GLY B 1 215 ? 43.643  64.777 56.940  1.00 0.46 ? 215 GLY B CA  1 
ATOM 4829 C C   . GLY B 1 215 ? 44.135  63.718 55.982  1.00 0.46 ? 215 GLY B C   1 
ATOM 4830 O O   . GLY B 1 215 ? 44.611  64.021 54.893  1.00 0.46 ? 215 GLY B O   1 
ATOM 4831 N N   . ASP B 1 216 ? 43.994  62.437 56.357  1.00 0.41 ? 216 ASP B N   1 
ATOM 4832 C CA  . ASP B 1 216 ? 44.327  61.293 55.528  1.00 0.41 ? 216 ASP B CA  1 
ATOM 4833 C C   . ASP B 1 216 ? 43.260  60.993 54.475  1.00 0.41 ? 216 ASP B C   1 
ATOM 4834 O O   . ASP B 1 216 ? 43.461  60.185 53.575  1.00 0.41 ? 216 ASP B O   1 
ATOM 4835 C CB  . ASP B 1 216 ? 44.569  60.047 56.417  1.00 0.41 ? 216 ASP B CB  1 
ATOM 4836 C CG  . ASP B 1 216 ? 45.853  60.196 57.218  1.00 0.41 ? 216 ASP B CG  1 
ATOM 4837 O OD1 . ASP B 1 216 ? 46.712  61.028 56.826  1.00 0.41 ? 216 ASP B OD1 1 
ATOM 4838 O OD2 . ASP B 1 216 ? 45.996  59.468 58.228  1.00 0.41 ? 216 ASP B OD2 1 
ATOM 4839 N N   . ALA B 1 217 ? 42.068  61.628 54.540  1.00 0.45 ? 217 ALA B N   1 
ATOM 4840 C CA  . ALA B 1 217 ? 41.081  61.522 53.483  1.00 0.45 ? 217 ALA B CA  1 
ATOM 4841 C C   . ALA B 1 217 ? 41.502  62.287 52.230  1.00 0.45 ? 217 ALA B C   1 
ATOM 4842 O O   . ALA B 1 217 ? 41.197  61.881 51.109  1.00 0.45 ? 217 ALA B O   1 
ATOM 4843 C CB  . ALA B 1 217 ? 39.698  61.973 53.986  1.00 0.45 ? 217 ALA B CB  1 
ATOM 4844 N N   . ALA B 1 218 ? 42.245  63.402 52.408  1.00 0.45 ? 218 ALA B N   1 
ATOM 4845 C CA  . ALA B 1 218 ? 42.922  64.115 51.349  1.00 0.45 ? 218 ALA B CA  1 
ATOM 4846 C C   . ALA B 1 218 ? 44.147  63.342 50.871  1.00 0.45 ? 218 ALA B C   1 
ATOM 4847 O O   . ALA B 1 218 ? 44.558  62.348 51.470  1.00 0.45 ? 218 ALA B O   1 
ATOM 4848 C CB  . ALA B 1 218 ? 43.337  65.522 51.833  1.00 0.45 ? 218 ALA B CB  1 
ATOM 4849 N N   . LEU B 1 219 ? 44.766  63.774 49.751  1.00 0.46 ? 219 LEU B N   1 
ATOM 4850 C CA  . LEU B 1 219 ? 45.858  63.054 49.113  1.00 0.46 ? 219 LEU B CA  1 
ATOM 4851 C C   . LEU B 1 219 ? 45.500  61.598 48.772  1.00 0.46 ? 219 LEU B C   1 
ATOM 4852 O O   . LEU B 1 219 ? 44.407  61.330 48.281  1.00 0.46 ? 219 LEU B O   1 
ATOM 4853 C CB  . LEU B 1 219 ? 47.177  63.168 49.931  1.00 0.46 ? 219 LEU B CB  1 
ATOM 4854 C CG  . LEU B 1 219 ? 47.550  64.604 50.353  1.00 0.46 ? 219 LEU B CG  1 
ATOM 4855 C CD1 . LEU B 1 219 ? 48.751  64.593 51.314  1.00 0.46 ? 219 LEU B CD1 1 
ATOM 4856 C CD2 . LEU B 1 219 ? 47.825  65.520 49.151  1.00 0.46 ? 219 LEU B CD2 1 
ATOM 4857 N N   . ALA B 1 220 ? 46.423  60.637 49.010  1.00 0.55 ? 220 ALA B N   1 
ATOM 4858 C CA  . ALA B 1 220 ? 46.146  59.222 49.223  1.00 0.55 ? 220 ALA B CA  1 
ATOM 4859 C C   . ALA B 1 220 ? 45.085  58.563 48.344  1.00 0.55 ? 220 ALA B C   1 
ATOM 4860 O O   . ALA B 1 220 ? 45.199  58.570 47.118  1.00 0.55 ? 220 ALA B O   1 
ATOM 4861 C CB  . ALA B 1 220 ? 45.933  59.017 50.734  1.00 0.55 ? 220 ALA B CB  1 
ATOM 4862 N N   . LEU B 1 221 ? 44.044  57.957 48.950  1.00 0.51 ? 221 LEU B N   1 
ATOM 4863 C CA  . LEU B 1 221 ? 42.959  57.283 48.248  1.00 0.51 ? 221 LEU B CA  1 
ATOM 4864 C C   . LEU B 1 221 ? 42.215  58.178 47.271  1.00 0.51 ? 221 LEU B C   1 
ATOM 4865 O O   . LEU B 1 221 ? 41.919  57.762 46.156  1.00 0.51 ? 221 LEU B O   1 
ATOM 4866 C CB  . LEU B 1 221 ? 41.977  56.669 49.276  1.00 0.51 ? 221 LEU B CB  1 
ATOM 4867 C CG  . LEU B 1 221 ? 40.863  55.732 48.780  1.00 0.51 ? 221 LEU B CG  1 
ATOM 4868 C CD1 . LEU B 1 221 ? 40.495  54.727 49.888  1.00 0.51 ? 221 LEU B CD1 1 
ATOM 4869 C CD2 . LEU B 1 221 ? 39.592  56.489 48.368  1.00 0.51 ? 221 LEU B CD2 1 
ATOM 4870 N N   . LEU B 1 222 ? 41.935  59.451 47.630  1.00 0.53 ? 222 LEU B N   1 
ATOM 4871 C CA  . LEU B 1 222 ? 41.267  60.405 46.764  1.00 0.53 ? 222 LEU B CA  1 
ATOM 4872 C C   . LEU B 1 222 ? 42.016  60.668 45.464  1.00 0.53 ? 222 LEU B C   1 
ATOM 4873 O O   . LEU B 1 222 ? 41.442  60.640 44.372  1.00 0.53 ? 222 LEU B O   1 
ATOM 4874 C CB  . LEU B 1 222 ? 41.136  61.735 47.553  1.00 0.53 ? 222 LEU B CB  1 
ATOM 4875 C CG  . LEU B 1 222 ? 40.802  63.003 46.745  1.00 0.53 ? 222 LEU B CG  1 
ATOM 4876 C CD1 . LEU B 1 222 ? 39.397  62.936 46.141  1.00 0.53 ? 222 LEU B CD1 1 
ATOM 4877 C CD2 . LEU B 1 222 ? 40.948  64.246 47.630  1.00 0.53 ? 222 LEU B CD2 1 
ATOM 4878 N N   . LEU B 1 223 ? 43.341  60.909 45.547  1.00 0.57 ? 223 LEU B N   1 
ATOM 4879 C CA  . LEU B 1 223 ? 44.178  61.062 44.373  1.00 0.57 ? 223 LEU B CA  1 
ATOM 4880 C C   . LEU B 1 223 ? 44.327  59.777 43.591  1.00 0.57 ? 223 LEU B C   1 
ATOM 4881 O O   . LEU B 1 223 ? 44.207  59.781 42.369  1.00 0.57 ? 223 LEU B O   1 
ATOM 4882 C CB  . LEU B 1 223 ? 45.576  61.630 44.706  1.00 0.57 ? 223 LEU B CB  1 
ATOM 4883 C CG  . LEU B 1 223 ? 45.570  63.071 45.257  1.00 0.57 ? 223 LEU B CG  1 
ATOM 4884 C CD1 . LEU B 1 223 ? 47.009  63.514 45.565  1.00 0.57 ? 223 LEU B CD1 1 
ATOM 4885 C CD2 . LEU B 1 223 ? 44.907  64.081 44.304  1.00 0.57 ? 223 LEU B CD2 1 
ATOM 4886 N N   . LEU B 1 224 ? 44.543  58.634 44.274  1.00 0.49 ? 224 LEU B N   1 
ATOM 4887 C CA  . LEU B 1 224 ? 44.637  57.341 43.625  1.00 0.49 ? 224 LEU B CA  1 
ATOM 4888 C C   . LEU B 1 224 ? 43.366  56.938 42.883  1.00 0.49 ? 224 LEU B C   1 
ATOM 4889 O O   . LEU B 1 224 ? 43.452  56.564 41.717  1.00 0.49 ? 224 LEU B O   1 
ATOM 4890 C CB  . LEU B 1 224 ? 45.051  56.238 44.630  1.00 0.49 ? 224 LEU B CB  1 
ATOM 4891 C CG  . LEU B 1 224 ? 46.520  56.316 45.109  1.00 0.49 ? 224 LEU B CG  1 
ATOM 4892 C CD1 . LEU B 1 224 ? 46.756  55.344 46.277  1.00 0.49 ? 224 LEU B CD1 1 
ATOM 4893 C CD2 . LEU B 1 224 ? 47.517  56.018 43.977  1.00 0.49 ? 224 LEU B CD2 1 
ATOM 4894 N N   . ASP B 1 225 ? 42.158  57.083 43.477  1.00 0.44 ? 225 ASP B N   1 
ATOM 4895 C CA  . ASP B 1 225 ? 40.901  56.834 42.789  1.00 0.44 ? 225 ASP B CA  1 
ATOM 4896 C C   . ASP B 1 225 ? 40.722  57.744 41.568  1.00 0.44 ? 225 ASP B C   1 
ATOM 4897 O O   . ASP B 1 225 ? 40.456  57.279 40.460  1.00 0.44 ? 225 ASP B O   1 
ATOM 4898 C CB  . ASP B 1 225 ? 39.678  57.091 43.729  1.00 0.44 ? 225 ASP B CB  1 
ATOM 4899 C CG  . ASP B 1 225 ? 39.220  55.940 44.613  1.00 0.44 ? 225 ASP B CG  1 
ATOM 4900 O OD1 . ASP B 1 225 ? 39.787  54.822 44.606  1.00 0.44 ? 225 ASP B OD1 1 
ATOM 4901 O OD2 . ASP B 1 225 ? 38.192  56.152 45.313  1.00 0.44 ? 225 ASP B OD2 1 
ATOM 4902 N N   . ARG B 1 226 ? 40.896  59.076 41.714  1.00 0.49 ? 226 ARG B N   1 
ATOM 4903 C CA  . ARG B 1 226 ? 40.671  60.005 40.615  1.00 0.49 ? 226 ARG B CA  1 
ATOM 4904 C C   . ARG B 1 226 ? 41.654  59.880 39.470  1.00 0.49 ? 226 ARG B C   1 
ATOM 4905 O O   . ARG B 1 226 ? 41.267  59.842 38.301  1.00 0.49 ? 226 ARG B O   1 
ATOM 4906 C CB  . ARG B 1 226 ? 40.668  61.472 41.119  1.00 0.49 ? 226 ARG B CB  1 
ATOM 4907 C CG  . ARG B 1 226 ? 39.452  61.808 42.007  1.00 0.49 ? 226 ARG B CG  1 
ATOM 4908 C CD  . ARG B 1 226 ? 38.288  62.575 41.348  1.00 0.49 ? 226 ARG B CD  1 
ATOM 4909 N NE  . ARG B 1 226 ? 37.871  61.982 40.034  1.00 0.49 ? 226 ARG B NE  1 
ATOM 4910 C CZ  . ARG B 1 226 ? 37.303  60.786 39.846  1.00 0.49 ? 226 ARG B CZ  1 
ATOM 4911 N NH1 . ARG B 1 226 ? 37.141  60.357 38.598  1.00 0.49 ? 226 ARG B NH1 1 
ATOM 4912 N NH2 . ARG B 1 226 ? 36.926  59.975 40.822  1.00 0.49 ? 226 ARG B NH2 1 
ATOM 4913 N N   . LEU B 1 227 ? 42.956  59.793 39.781  1.00 0.53 ? 227 LEU B N   1 
ATOM 4914 C CA  . LEU B 1 227 ? 43.993  59.645 38.789  1.00 0.53 ? 227 LEU B CA  1 
ATOM 4915 C C   . LEU B 1 227 ? 44.010  58.269 38.143  1.00 0.53 ? 227 LEU B C   1 
ATOM 4916 O O   . LEU B 1 227 ? 44.145  58.177 36.926  1.00 0.53 ? 227 LEU B O   1 
ATOM 4917 C CB  . LEU B 1 227 ? 45.368  60.044 39.369  1.00 0.53 ? 227 LEU B CB  1 
ATOM 4918 C CG  . LEU B 1 227 ? 45.441  61.509 39.867  1.00 0.53 ? 227 LEU B CG  1 
ATOM 4919 C CD1 . LEU B 1 227 ? 46.799  61.779 40.535  1.00 0.53 ? 227 LEU B CD1 1 
ATOM 4920 C CD2 . LEU B 1 227 ? 45.171  62.544 38.758  1.00 0.53 ? 227 LEU B CD2 1 
ATOM 4921 N N   . ASN B 1 228 ? 43.816  57.164 38.911  1.00 0.39 ? 228 ASN B N   1 
ATOM 4922 C CA  . ASN B 1 228 ? 43.705  55.820 38.349  1.00 0.39 ? 228 ASN B CA  1 
ATOM 4923 C C   . ASN B 1 228 ? 42.454  55.648 37.487  1.00 0.39 ? 228 ASN B C   1 
ATOM 4924 O O   . ASN B 1 228 ? 42.492  54.964 36.470  1.00 0.39 ? 228 ASN B O   1 
ATOM 4925 C CB  . ASN B 1 228 ? 43.850  54.651 39.373  1.00 0.39 ? 228 ASN B CB  1 
ATOM 4926 C CG  . ASN B 1 228 ? 45.225  54.540 40.044  1.00 0.39 ? 228 ASN B CG  1 
ATOM 4927 O OD1 . ASN B 1 228 ? 45.429  53.731 40.958  1.00 0.39 ? 228 ASN B OD1 1 
ATOM 4928 N ND2 . ASN B 1 228 ? 46.243  55.284 39.565  1.00 0.39 ? 228 ASN B ND2 1 
ATOM 4929 N N   . GLN B 1 229 ? 41.311  56.291 37.820  1.00 0.45 ? 229 GLN B N   1 
ATOM 4930 C CA  . GLN B 1 229 ? 40.152  56.315 36.933  1.00 0.45 ? 229 GLN B CA  1 
ATOM 4931 C C   . GLN B 1 229 ? 40.374  57.011 35.596  1.00 0.45 ? 229 GLN B C   1 
ATOM 4932 O O   . GLN B 1 229 ? 39.973  56.496 34.554  1.00 0.45 ? 229 GLN B O   1 
ATOM 4933 C CB  . GLN B 1 229 ? 38.916  56.940 37.618  1.00 0.45 ? 229 GLN B CB  1 
ATOM 4934 C CG  . GLN B 1 229 ? 38.221  55.936 38.556  1.00 0.45 ? 229 GLN B CG  1 
ATOM 4935 C CD  . GLN B 1 229 ? 36.938  56.493 39.171  1.00 0.45 ? 229 GLN B CD  1 
ATOM 4936 O OE1 . GLN B 1 229 ? 36.616  57.684 39.126  1.00 0.45 ? 229 GLN B OE1 1 
ATOM 4937 N NE2 . GLN B 1 229 ? 36.149  55.569 39.763  1.00 0.45 ? 229 GLN B NE2 1 
ATOM 4938 N N   . LEU B 1 230 ? 41.036  58.185 35.583  1.00 0.48 ? 230 LEU B N   1 
ATOM 4939 C CA  . LEU B 1 230 ? 41.452  58.871 34.366  1.00 0.48 ? 230 LEU B CA  1 
ATOM 4940 C C   . LEU B 1 230 ? 42.453  58.065 33.536  1.00 0.48 ? 230 LEU B C   1 
ATOM 4941 O O   . LEU B 1 230 ? 42.354  57.977 32.314  1.00 0.48 ? 230 LEU B O   1 
ATOM 4942 C CB  . LEU B 1 230 ? 42.030  60.260 34.724  1.00 0.48 ? 230 LEU B CB  1 
ATOM 4943 C CG  . LEU B 1 230 ? 40.964  61.280 35.183  1.00 0.48 ? 230 LEU B CG  1 
ATOM 4944 C CD1 . LEU B 1 230 ? 41.600  62.456 35.941  1.00 0.48 ? 230 LEU B CD1 1 
ATOM 4945 C CD2 . LEU B 1 230 ? 40.139  61.800 33.992  1.00 0.48 ? 230 LEU B CD2 1 
ATOM 4946 N N   . GLU B 1 231 ? 43.410  57.410 34.217  1.00 0.49 ? 231 GLU B N   1 
ATOM 4947 C CA  . GLU B 1 231 ? 44.410  56.507 33.676  1.00 0.49 ? 231 GLU B CA  1 
ATOM 4948 C C   . GLU B 1 231 ? 43.855  55.180 33.131  1.00 0.49 ? 231 GLU B C   1 
ATOM 4949 O O   . GLU B 1 231 ? 44.486  54.553 32.282  1.00 0.49 ? 231 GLU B O   1 
ATOM 4950 C CB  . GLU B 1 231 ? 45.425  56.253 34.822  1.00 0.49 ? 231 GLU B CB  1 
ATOM 4951 C CG  . GLU B 1 231 ? 46.436  55.088 34.681  1.00 0.49 ? 231 GLU B CG  1 
ATOM 4952 C CD  . GLU B 1 231 ? 47.309  54.873 35.904  1.00 0.49 ? 231 GLU B CD  1 
ATOM 4953 O OE1 . GLU B 1 231 ? 47.235  55.675 36.872  1.00 0.49 ? 231 GLU B OE1 1 
ATOM 4954 O OE2 . GLU B 1 231 ? 48.115  53.901 35.913  1.00 0.49 ? 231 GLU B OE2 1 
ATOM 4955 N N   . SER B 1 232 ? 42.652  54.734 33.577  1.00 0.47 ? 232 SER B N   1 
ATOM 4956 C CA  . SER B 1 232 ? 42.071  53.413 33.291  1.00 0.47 ? 232 SER B CA  1 
ATOM 4957 C C   . SER B 1 232 ? 41.935  53.110 31.808  1.00 0.47 ? 232 SER B C   1 
ATOM 4958 O O   . SER B 1 232 ? 42.350  52.060 31.324  1.00 0.47 ? 232 SER B O   1 
ATOM 4959 C CB  . SER B 1 232 ? 40.681  53.247 33.998  1.00 0.47 ? 232 SER B CB  1 
ATOM 4960 O OG  . SER B 1 232 ? 39.991  52.038 33.668  1.00 0.47 ? 232 SER B OG  1 
ATOM 4961 N N   . LYS B 1 233 ? 41.414  54.073 31.024  1.00 0.45 ? 233 LYS B N   1 
ATOM 4962 C CA  . LYS B 1 233 ? 41.476  53.979 29.581  1.00 0.45 ? 233 LYS B CA  1 
ATOM 4963 C C   . LYS B 1 233 ? 42.637  54.788 29.027  1.00 0.45 ? 233 LYS B C   1 
ATOM 4964 O O   . LYS B 1 233 ? 43.526  54.245 28.371  1.00 0.45 ? 233 LYS B O   1 
ATOM 4965 C CB  . LYS B 1 233 ? 40.132  54.407 28.944  1.00 0.45 ? 233 LYS B CB  1 
ATOM 4966 C CG  . LYS B 1 233 ? 38.996  53.422 29.272  1.00 0.45 ? 233 LYS B CG  1 
ATOM 4967 C CD  . LYS B 1 233 ? 37.669  53.722 28.552  1.00 0.45 ? 233 LYS B CD  1 
ATOM 4968 C CE  . LYS B 1 233 ? 37.747  53.496 27.038  1.00 0.45 ? 233 LYS B CE  1 
ATOM 4969 N NZ  . LYS B 1 233 ? 36.398  53.568 26.433  1.00 0.45 ? 233 LYS B NZ  1 
ATOM 4970 N N   . MET B 1 234 ? 42.658  56.119 29.272  1.00 0.43 ? 234 MET B N   1 
ATOM 4971 C CA  . MET B 1 234 ? 43.709  57.035 28.855  1.00 0.43 ? 234 MET B CA  1 
ATOM 4972 C C   . MET B 1 234 ? 43.926  57.100 27.341  1.00 0.43 ? 234 MET B C   1 
ATOM 4973 O O   . MET B 1 234 ? 45.009  57.385 26.818  1.00 0.43 ? 234 MET B O   1 
ATOM 4974 C CB  . MET B 1 234 ? 44.999  56.798 29.682  1.00 0.43 ? 234 MET B CB  1 
ATOM 4975 C CG  . MET B 1 234 ? 46.013  57.959 29.702  1.00 0.43 ? 234 MET B CG  1 
ATOM 4976 S SD  . MET B 1 234 ? 47.144  57.895 31.123  1.00 0.43 ? 234 MET B SD  1 
ATOM 4977 C CE  . MET B 1 234 ? 48.161  59.313 30.621  1.00 0.43 ? 234 MET B CE  1 
ATOM 4978 N N   . SER B 1 235 ? 42.836  56.868 26.588  1.00 0.44 ? 235 SER B N   1 
ATOM 4979 C CA  . SER B 1 235 ? 42.760  56.869 25.143  1.00 0.44 ? 235 SER B CA  1 
ATOM 4980 C C   . SER B 1 235 ? 42.785  58.280 24.563  1.00 0.44 ? 235 SER B C   1 
ATOM 4981 O O   . SER B 1 235 ? 42.747  59.281 25.273  1.00 0.44 ? 235 SER B O   1 
ATOM 4982 C CB  . SER B 1 235 ? 41.562  56.005 24.636  1.00 0.44 ? 235 SER B CB  1 
ATOM 4983 O OG  . SER B 1 235 ? 40.412  56.025 25.490  1.00 0.44 ? 235 SER B OG  1 
ATOM 4984 N N   . GLY B 1 236 ? 42.968  58.419 23.232  1.00 0.48 ? 236 GLY B N   1 
ATOM 4985 C CA  . GLY B 1 236 ? 42.990  59.737 22.616  1.00 0.48 ? 236 GLY B CA  1 
ATOM 4986 C C   . GLY B 1 236 ? 42.796  59.627 21.133  1.00 0.48 ? 236 GLY B C   1 
ATOM 4987 O O   . GLY B 1 236 ? 42.767  58.529 20.587  1.00 0.48 ? 236 GLY B O   1 
ATOM 4988 N N   . LYS B 1 237 ? 42.707  60.784 20.441  1.00 0.28 ? 237 LYS B N   1 
ATOM 4989 C CA  . LYS B 1 237 ? 42.273  60.919 19.051  1.00 0.28 ? 237 LYS B CA  1 
ATOM 4990 C C   . LYS B 1 237 ? 43.165  60.259 18.002  1.00 0.28 ? 237 LYS B C   1 
ATOM 4991 O O   . LYS B 1 237 ? 42.726  59.963 16.895  1.00 0.28 ? 237 LYS B O   1 
ATOM 4992 C CB  . LYS B 1 237 ? 42.108  62.435 18.728  1.00 0.28 ? 237 LYS B CB  1 
ATOM 4993 C CG  . LYS B 1 237 ? 41.503  62.811 17.353  1.00 0.28 ? 237 LYS B CG  1 
ATOM 4994 C CD  . LYS B 1 237 ? 40.083  62.259 17.114  1.00 0.28 ? 237 LYS B CD  1 
ATOM 4995 C CE  . LYS B 1 237 ? 39.461  62.641 15.763  1.00 0.28 ? 237 LYS B CE  1 
ATOM 4996 N NZ  . LYS B 1 237 ? 39.088  64.074 15.747  1.00 0.28 ? 237 LYS B NZ  1 
ATOM 4997 N N   . GLY B 1 238 ? 44.442  59.984 18.335  1.00 0.40 ? 238 GLY B N   1 
ATOM 4998 C CA  . GLY B 1 238 ? 45.361  59.259 17.462  1.00 0.40 ? 238 GLY B CA  1 
ATOM 4999 C C   . GLY B 1 238 ? 45.177  57.758 17.435  1.00 0.40 ? 238 GLY B C   1 
ATOM 5000 O O   . GLY B 1 238 ? 45.886  57.062 16.717  1.00 0.40 ? 238 GLY B O   1 
ATOM 5001 N N   . GLN B 1 239 ? 44.245  57.201 18.230  1.00 0.39 ? 239 GLN B N   1 
ATOM 5002 C CA  . GLN B 1 239 ? 44.000  55.773 18.284  1.00 0.39 ? 239 GLN B CA  1 
ATOM 5003 C C   . GLN B 1 239 ? 42.632  55.461 17.704  1.00 0.39 ? 239 GLN B C   1 
ATOM 5004 O O   . GLN B 1 239 ? 41.646  56.109 18.041  1.00 0.39 ? 239 GLN B O   1 
ATOM 5005 C CB  . GLN B 1 239 ? 43.996  55.273 19.752  1.00 0.39 ? 239 GLN B CB  1 
ATOM 5006 C CG  . GLN B 1 239 ? 45.354  55.459 20.468  1.00 0.39 ? 239 GLN B CG  1 
ATOM 5007 C CD  . GLN B 1 239 ? 45.243  55.326 21.984  1.00 0.39 ? 239 GLN B CD  1 
ATOM 5008 O OE1 . GLN B 1 239 ? 45.517  56.268 22.736  1.00 0.39 ? 239 GLN B OE1 1 
ATOM 5009 N NE2 . GLN B 1 239 ? 44.853  54.119 22.448  1.00 0.39 ? 239 GLN B NE2 1 
ATOM 5010 N N   . GLN B 1 240 ? 42.528  54.438 16.822  1.00 0.33 ? 240 GLN B N   1 
ATOM 5011 C CA  . GLN B 1 240 ? 41.244  54.007 16.283  1.00 0.33 ? 240 GLN B CA  1 
ATOM 5012 C C   . GLN B 1 240 ? 40.338  53.314 17.297  1.00 0.33 ? 240 GLN B C   1 
ATOM 5013 O O   . GLN B 1 240 ? 39.163  53.642 17.435  1.00 0.33 ? 240 GLN B O   1 
ATOM 5014 C CB  . GLN B 1 240 ? 41.473  53.051 15.084  1.00 0.33 ? 240 GLN B CB  1 
ATOM 5015 C CG  . GLN B 1 240 ? 40.169  52.563 14.398  1.00 0.33 ? 240 GLN B CG  1 
ATOM 5016 C CD  . GLN B 1 240 ? 40.460  51.757 13.131  1.00 0.33 ? 240 GLN B CD  1 
ATOM 5017 O OE1 . GLN B 1 240 ? 41.599  51.468 12.773  1.00 0.33 ? 240 GLN B OE1 1 
ATOM 5018 N NE2 . GLN B 1 240 ? 39.372  51.374 12.420  1.00 0.33 ? 240 GLN B NE2 1 
ATOM 5019 N N   . GLN B 1 241 ? 40.875  52.336 18.052  1.00 0.41 ? 241 GLN B N   1 
ATOM 5020 C CA  . GLN B 1 241 ? 40.122  51.633 19.068  1.00 0.41 ? 241 GLN B CA  1 
ATOM 5021 C C   . GLN B 1 241 ? 41.105  50.918 19.977  1.00 0.41 ? 241 GLN B C   1 
ATOM 5022 O O   . GLN B 1 241 ? 41.956  50.164 19.519  1.00 0.41 ? 241 GLN B O   1 
ATOM 5023 C CB  . GLN B 1 241 ? 39.098  50.636 18.458  1.00 0.41 ? 241 GLN B CB  1 
ATOM 5024 C CG  . GLN B 1 241 ? 38.310  49.806 19.499  1.00 0.41 ? 241 GLN B CG  1 
ATOM 5025 C CD  . GLN B 1 241 ? 36.978  49.251 18.986  1.00 0.41 ? 241 GLN B CD  1 
ATOM 5026 O OE1 . GLN B 1 241 ? 36.016  49.187 19.751  1.00 0.41 ? 241 GLN B OE1 1 
ATOM 5027 N NE2 . GLN B 1 241 ? 36.913  48.823 17.708  1.00 0.41 ? 241 GLN B NE2 1 
ATOM 5028 N N   . GLN B 1 242 ? 41.064  51.190 21.303  1.00 0.44 ? 242 GLN B N   1 
ATOM 5029 C CA  . GLN B 1 242 ? 41.991  50.589 22.256  1.00 0.44 ? 242 GLN B CA  1 
ATOM 5030 C C   . GLN B 1 242 ? 41.657  49.153 22.647  1.00 0.44 ? 242 GLN B C   1 
ATOM 5031 O O   . GLN B 1 242 ? 42.530  48.299 22.765  1.00 0.44 ? 242 GLN B O   1 
ATOM 5032 C CB  . GLN B 1 242 ? 42.138  51.504 23.499  1.00 0.44 ? 242 GLN B CB  1 
ATOM 5033 C CG  . GLN B 1 242 ? 43.276  51.094 24.472  1.00 0.44 ? 242 GLN B CG  1 
ATOM 5034 C CD  . GLN B 1 242 ? 43.686  52.256 25.386  1.00 0.44 ? 242 GLN B CD  1 
ATOM 5035 O OE1 . GLN B 1 242 ? 43.796  53.397 24.929  1.00 0.44 ? 242 GLN B OE1 1 
ATOM 5036 N NE2 . GLN B 1 242 ? 43.956  51.975 26.677  1.00 0.44 ? 242 GLN B NE2 1 
ATOM 5037 N N   . GLY B 1 243 ? 40.359  48.838 22.860  1.00 0.52 ? 243 GLY B N   1 
ATOM 5038 C CA  . GLY B 1 243 ? 39.903  47.450 22.977  1.00 0.52 ? 243 GLY B CA  1 
ATOM 5039 C C   . GLY B 1 243 ? 40.187  46.713 24.261  1.00 0.52 ? 243 GLY B C   1 
ATOM 5040 O O   . GLY B 1 243 ? 40.007  45.498 24.328  1.00 0.52 ? 243 GLY B O   1 
ATOM 5041 N N   . GLN B 1 244 ? 40.658  47.408 25.310  1.00 0.49 ? 244 GLN B N   1 
ATOM 5042 C CA  . GLN B 1 244 ? 41.100  46.768 26.538  1.00 0.49 ? 244 GLN B CA  1 
ATOM 5043 C C   . GLN B 1 244 ? 40.050  46.681 27.637  1.00 0.49 ? 244 GLN B C   1 
ATOM 5044 O O   . GLN B 1 244 ? 40.261  45.972 28.615  1.00 0.49 ? 244 GLN B O   1 
ATOM 5045 C CB  . GLN B 1 244 ? 42.325  47.531 27.088  1.00 0.49 ? 244 GLN B CB  1 
ATOM 5046 C CG  . GLN B 1 244 ? 43.575  47.346 26.197  1.00 0.49 ? 244 GLN B CG  1 
ATOM 5047 C CD  . GLN B 1 244 ? 44.754  48.171 26.707  1.00 0.49 ? 244 GLN B CD  1 
ATOM 5048 O OE1 . GLN B 1 244 ? 44.585  49.288 27.197  1.00 0.49 ? 244 GLN B OE1 1 
ATOM 5049 N NE2 . GLN B 1 244 ? 45.989  47.644 26.546  1.00 0.49 ? 244 GLN B NE2 1 
ATOM 5050 N N   . THR B 1 245 ? 38.906  47.388 27.483  1.00 0.44 ? 245 THR B N   1 
ATOM 5051 C CA  . THR B 1 245 ? 37.688  47.256 28.299  1.00 0.44 ? 245 THR B CA  1 
ATOM 5052 C C   . THR B 1 245 ? 37.874  47.310 29.816  1.00 0.44 ? 245 THR B C   1 
ATOM 5053 O O   . THR B 1 245 ? 37.250  46.575 30.578  1.00 0.44 ? 245 THR B O   1 
ATOM 5054 C CB  . THR B 1 245 ? 36.763  46.110 27.864  1.00 0.44 ? 245 THR B CB  1 
ATOM 5055 O OG1 . THR B 1 245 ? 37.375  44.831 27.919  1.00 0.44 ? 245 THR B OG1 1 
ATOM 5056 C CG2 . THR B 1 245 ? 36.374  46.286 26.388  1.00 0.44 ? 245 THR B CG2 1 
ATOM 5057 N N   . VAL B 1 246 ? 38.729  48.241 30.294  1.00 0.37 ? 246 VAL B N   1 
ATOM 5058 C CA  . VAL B 1 246 ? 39.127  48.372 31.687  1.00 0.37 ? 246 VAL B CA  1 
ATOM 5059 C C   . VAL B 1 246 ? 38.021  48.931 32.591  1.00 0.37 ? 246 VAL B C   1 
ATOM 5060 O O   . VAL B 1 246 ? 37.177  49.735 32.187  1.00 0.37 ? 246 VAL B O   1 
ATOM 5061 C CB  . VAL B 1 246 ? 40.436  49.153 31.823  1.00 0.37 ? 246 VAL B CB  1 
ATOM 5062 C CG1 . VAL B 1 246 ? 41.070  48.967 33.219  1.00 0.37 ? 246 VAL B CG1 1 
ATOM 5063 C CG2 . VAL B 1 246 ? 41.451  48.702 30.745  1.00 0.37 ? 246 VAL B CG2 1 
ATOM 5064 N N   . THR B 1 247 ? 37.983  48.473 33.860  1.00 0.45 ? 247 THR B N   1 
ATOM 5065 C CA  . THR B 1 247 ? 36.989  48.815 34.862  1.00 0.45 ? 247 THR B CA  1 
ATOM 5066 C C   . THR B 1 247 ? 37.112  50.230 35.419  1.00 0.45 ? 247 THR B C   1 
ATOM 5067 O O   . THR B 1 247 ? 38.149  50.889 35.367  1.00 0.45 ? 247 THR B O   1 
ATOM 5068 C CB  . THR B 1 247 ? 36.956  47.818 36.027  1.00 0.45 ? 247 THR B CB  1 
ATOM 5069 O OG1 . THR B 1 247 ? 38.212  47.705 36.682  1.00 0.45 ? 247 THR B OG1 1 
ATOM 5070 C CG2 . THR B 1 247 ? 36.618  46.410 35.514  1.00 0.45 ? 247 THR B CG2 1 
ATOM 5071 N N   . LYS B 1 248 ? 36.006  50.760 35.989  1.00 0.46 ? 248 LYS B N   1 
ATOM 5072 C CA  . LYS B 1 248 ? 36.027  52.031 36.695  1.00 0.46 ? 248 LYS B CA  1 
ATOM 5073 C C   . LYS B 1 248 ? 36.350  51.883 38.180  1.00 0.46 ? 248 LYS B C   1 
ATOM 5074 O O   . LYS B 1 248 ? 36.610  52.874 38.860  1.00 0.46 ? 248 LYS B O   1 
ATOM 5075 C CB  . LYS B 1 248 ? 34.632  52.705 36.619  1.00 0.46 ? 248 LYS B CB  1 
ATOM 5076 C CG  . LYS B 1 248 ? 34.169  53.034 35.189  1.00 0.46 ? 248 LYS B CG  1 
ATOM 5077 C CD  . LYS B 1 248 ? 32.810  53.760 35.177  1.00 0.46 ? 248 LYS B CD  1 
ATOM 5078 C CE  . LYS B 1 248 ? 32.293  54.151 33.786  1.00 0.46 ? 248 LYS B CE  1 
ATOM 5079 N NZ  . LYS B 1 248 ? 31.852  52.949 33.040  1.00 0.46 ? 248 LYS B NZ  1 
ATOM 5080 N N   . LYS B 1 249 ? 36.309  50.651 38.730  1.00 0.40 ? 249 LYS B N   1 
ATOM 5081 C CA  . LYS B 1 249 ? 36.452  50.395 40.151  1.00 0.40 ? 249 LYS B CA  1 
ATOM 5082 C C   . LYS B 1 249 ? 37.044  49.013 40.356  1.00 0.40 ? 249 LYS B C   1 
ATOM 5083 O O   . LYS B 1 249 ? 37.057  48.197 39.431  1.00 0.40 ? 249 LYS B O   1 
ATOM 5084 C CB  . LYS B 1 249 ? 35.086  50.391 40.895  1.00 0.40 ? 249 LYS B CB  1 
ATOM 5085 C CG  . LYS B 1 249 ? 34.386  51.755 40.946  1.00 0.40 ? 249 LYS B CG  1 
ATOM 5086 C CD  . LYS B 1 249 ? 33.098  51.758 41.791  1.00 0.40 ? 249 LYS B CD  1 
ATOM 5087 C CE  . LYS B 1 249 ? 31.996  50.846 41.235  1.00 0.40 ? 249 LYS B CE  1 
ATOM 5088 N NZ  . LYS B 1 249 ? 30.759  50.948 42.044  1.00 0.40 ? 249 LYS B NZ  1 
ATOM 5089 N N   . SER B 1 250 ? 37.514  48.727 41.591  1.00 0.45 ? 250 SER B N   1 
ATOM 5090 C CA  . SER B 1 250 ? 38.231  47.510 41.931  1.00 0.45 ? 250 SER B CA  1 
ATOM 5091 C C   . SER B 1 250 ? 37.706  46.912 43.206  1.00 0.45 ? 250 SER B C   1 
ATOM 5092 O O   . SER B 1 250 ? 37.438  47.630 44.165  1.00 0.45 ? 250 SER B O   1 
ATOM 5093 C CB  . SER B 1 250 ? 39.718  47.765 42.222  1.00 0.45 ? 250 SER B CB  1 
ATOM 5094 O OG  . SER B 1 250 ? 40.311  48.432 41.112  1.00 0.45 ? 250 SER B OG  1 
ATOM 5095 N N   . ALA B 1 251 ? 37.542  45.572 43.249  1.00 0.35 ? 251 ALA B N   1 
ATOM 5096 C CA  . ALA B 1 251 ? 37.212  44.832 44.456  1.00 0.35 ? 251 ALA B CA  1 
ATOM 5097 C C   . ALA B 1 251 ? 38.391  44.687 45.423  1.00 0.35 ? 251 ALA B C   1 
ATOM 5098 O O   . ALA B 1 251 ? 38.255  44.814 46.637  1.00 0.35 ? 251 ALA B O   1 
ATOM 5099 C CB  . ALA B 1 251 ? 36.664  43.441 44.064  1.00 0.35 ? 251 ALA B CB  1 
ATOM 5100 N N   . ALA B 1 252 ? 39.596  44.403 44.887  1.00 0.47 ? 252 ALA B N   1 
ATOM 5101 C CA  . ALA B 1 252 ? 40.824  44.310 45.645  1.00 0.47 ? 252 ALA B CA  1 
ATOM 5102 C C   . ALA B 1 252 ? 41.332  45.645 46.185  1.00 0.47 ? 252 ALA B C   1 
ATOM 5103 O O   . ALA B 1 252 ? 41.193  46.701 45.572  1.00 0.47 ? 252 ALA B O   1 
ATOM 5104 C CB  . ALA B 1 252 ? 41.915  43.640 44.784  1.00 0.47 ? 252 ALA B CB  1 
ATOM 5105 N N   . GLU B 1 253 ? 42.013  45.619 47.350  1.00 0.52 ? 253 GLU B N   1 
ATOM 5106 C CA  . GLU B 1 253 ? 42.470  46.821 48.023  1.00 0.52 ? 253 GLU B CA  1 
ATOM 5107 C C   . GLU B 1 253 ? 43.735  47.440 47.441  1.00 0.52 ? 253 GLU B C   1 
ATOM 5108 O O   . GLU B 1 253 ? 44.196  48.491 47.881  1.00 0.52 ? 253 GLU B O   1 
ATOM 5109 C CB  . GLU B 1 253 ? 42.731  46.520 49.507  1.00 0.52 ? 253 GLU B CB  1 
ATOM 5110 C CG  . GLU B 1 253 ? 41.445  46.173 50.283  1.00 0.52 ? 253 GLU B CG  1 
ATOM 5111 C CD  . GLU B 1 253 ? 41.721  46.329 51.778  1.00 0.52 ? 253 GLU B CD  1 
ATOM 5112 O OE1 . GLU B 1 253 ? 42.592  45.594 52.300  1.00 0.52 ? 253 GLU B OE1 1 
ATOM 5113 O OE2 . GLU B 1 253 ? 41.126  47.271 52.369  1.00 0.52 ? 253 GLU B OE2 1 
ATOM 5114 N N   . ALA B 1 254 ? 44.337  46.810 46.421  1.00 0.56 ? 254 ALA B N   1 
ATOM 5115 C CA  . ALA B 1 254 ? 45.528  47.273 45.741  1.00 0.56 ? 254 ALA B CA  1 
ATOM 5116 C C   . ALA B 1 254 ? 45.389  48.649 45.078  1.00 0.56 ? 254 ALA B C   1 
ATOM 5117 O O   . ALA B 1 254 ? 46.331  49.442 45.087  1.00 0.56 ? 254 ALA B O   1 
ATOM 5118 C CB  . ALA B 1 254 ? 45.959  46.204 44.724  1.00 0.56 ? 254 ALA B CB  1 
ATOM 5119 N N   . SER B 1 255 ? 44.200  48.996 44.532  1.00 0.54 ? 255 SER B N   1 
ATOM 5120 C CA  . SER B 1 255 ? 43.962  50.283 43.879  1.00 0.54 ? 255 SER B CA  1 
ATOM 5121 C C   . SER B 1 255 ? 44.001  51.490 44.780  1.00 0.54 ? 255 SER B C   1 
ATOM 5122 O O   . SER B 1 255 ? 44.268  52.596 44.319  1.00 0.54 ? 255 SER B O   1 
ATOM 5123 C CB  . SER B 1 255 ? 42.624  50.357 43.124  1.00 0.54 ? 255 SER B CB  1 
ATOM 5124 O OG  . SER B 1 255 ? 42.668  49.426 42.056  1.00 0.54 ? 255 SER B OG  1 
ATOM 5125 N N   . LYS B 1 256 ? 43.795  51.317 46.099  1.00 0.52 ? 256 LYS B N   1 
ATOM 5126 C CA  . LYS B 1 256 ? 43.904  52.407 47.047  1.00 0.52 ? 256 LYS B CA  1 
ATOM 5127 C C   . LYS B 1 256 ? 45.285  52.436 47.696  1.00 0.52 ? 256 LYS B C   1 
ATOM 5128 O O   . LYS B 1 256 ? 45.500  53.178 48.650  1.00 0.52 ? 256 LYS B O   1 
ATOM 5129 C CB  . LYS B 1 256 ? 42.789  52.365 48.134  1.00 0.52 ? 256 LYS B CB  1 
ATOM 5130 C CG  . LYS B 1 256 ? 42.716  51.072 48.960  1.00 0.52 ? 256 LYS B CG  1 
ATOM 5131 C CD  . LYS B 1 256 ? 41.750  51.145 50.161  1.00 0.52 ? 256 LYS B CD  1 
ATOM 5132 C CE  . LYS B 1 256 ? 41.684  49.805 50.893  1.00 0.52 ? 256 LYS B CE  1 
ATOM 5133 N NZ  . LYS B 1 256 ? 40.796  49.796 52.077  1.00 0.52 ? 256 LYS B NZ  1 
ATOM 5134 N N   . LYS B 1 257 ? 46.270  51.652 47.192  1.00 0.49 ? 257 LYS B N   1 
ATOM 5135 C CA  . LYS B 1 257 ? 47.611  51.594 47.755  1.00 0.49 ? 257 LYS B CA  1 
ATOM 5136 C C   . LYS B 1 257 ? 48.673  51.973 46.717  1.00 0.49 ? 257 LYS B C   1 
ATOM 5137 O O   . LYS B 1 257 ? 48.401  51.863 45.516  1.00 0.49 ? 257 LYS B O   1 
ATOM 5138 C CB  . LYS B 1 257 ? 47.892  50.181 48.329  1.00 0.49 ? 257 LYS B CB  1 
ATOM 5139 C CG  . LYS B 1 257 ? 47.065  49.910 49.597  1.00 0.49 ? 257 LYS B CG  1 
ATOM 5140 C CD  . LYS B 1 257 ? 47.403  48.591 50.315  1.00 0.49 ? 257 LYS B CD  1 
ATOM 5141 C CE  . LYS B 1 257 ? 47.016  47.342 49.516  1.00 0.49 ? 257 LYS B CE  1 
ATOM 5142 N NZ  . LYS B 1 257 ? 47.278  46.110 50.297  1.00 0.49 ? 257 LYS B NZ  1 
ATOM 5143 N N   . PRO B 1 258 ? 49.876  52.457 47.084  1.00 0.54 ? 258 PRO B N   1 
ATOM 5144 C CA  . PRO B 1 258 ? 50.942  52.808 46.139  1.00 0.54 ? 258 PRO B CA  1 
ATOM 5145 C C   . PRO B 1 258 ? 51.404  51.678 45.230  1.00 0.54 ? 258 PRO B C   1 
ATOM 5146 O O   . PRO B 1 258 ? 51.243  50.512 45.583  1.00 0.54 ? 258 PRO B O   1 
ATOM 5147 C CB  . PRO B 1 258 ? 52.100  53.306 47.026  1.00 0.54 ? 258 PRO B CB  1 
ATOM 5148 C CG  . PRO B 1 258 ? 51.428  53.717 48.334  1.00 0.54 ? 258 PRO B CG  1 
ATOM 5149 C CD  . PRO B 1 258 ? 50.301  52.695 48.466  1.00 0.54 ? 258 PRO B CD  1 
ATOM 5150 N N   . ARG B 1 259 ? 52.019  52.005 44.068  1.00 0.52 ? 259 ARG B N   1 
ATOM 5151 C CA  . ARG B 1 259 ? 52.355  51.069 43.002  1.00 0.52 ? 259 ARG B CA  1 
ATOM 5152 C C   . ARG B 1 259 ? 53.255  49.916 43.415  1.00 0.52 ? 259 ARG B C   1 
ATOM 5153 O O   . ARG B 1 259 ? 53.023  48.778 43.025  1.00 0.52 ? 259 ARG B O   1 
ATOM 5154 C CB  . ARG B 1 259 ? 53.027  51.791 41.803  1.00 0.52 ? 259 ARG B CB  1 
ATOM 5155 C CG  . ARG B 1 259 ? 52.237  52.977 41.196  1.00 0.52 ? 259 ARG B CG  1 
ATOM 5156 C CD  . ARG B 1 259 ? 50.859  52.640 40.600  1.00 0.52 ? 259 ARG B CD  1 
ATOM 5157 N NE  . ARG B 1 259 ? 50.294  53.938 40.084  1.00 0.52 ? 259 ARG B NE  1 
ATOM 5158 C CZ  . ARG B 1 259 ? 49.554  54.088 38.976  1.00 0.52 ? 259 ARG B CZ  1 
ATOM 5159 N NH1 . ARG B 1 259 ? 49.256  55.306 38.530  1.00 0.52 ? 259 ARG B NH1 1 
ATOM 5160 N NH2 . ARG B 1 259 ? 49.063  53.079 38.269  1.00 0.52 ? 259 ARG B NH2 1 
ATOM 5161 N N   . GLN B 1 260 ? 54.261  50.184 44.262  1.00 0.53 ? 260 GLN B N   1 
ATOM 5162 C CA  . GLN B 1 260 ? 55.216  49.220 44.765  1.00 0.53 ? 260 GLN B CA  1 
ATOM 5163 C C   . GLN B 1 260 ? 54.647  48.240 45.791  1.00 0.53 ? 260 GLN B C   1 
ATOM 5164 O O   . GLN B 1 260 ? 55.298  47.267 46.167  1.00 0.53 ? 260 GLN B O   1 
ATOM 5165 C CB  . GLN B 1 260 ? 56.451  49.952 45.365  1.00 0.53 ? 260 GLN B CB  1 
ATOM 5166 C CG  . GLN B 1 260 ? 56.242  50.778 46.669  1.00 0.53 ? 260 GLN B CG  1 
ATOM 5167 C CD  . GLN B 1 260 ? 55.697  52.199 46.473  1.00 0.53 ? 260 GLN B CD  1 
ATOM 5168 O OE1 . GLN B 1 260 ? 54.986  52.536 45.526  1.00 0.53 ? 260 GLN B OE1 1 
ATOM 5169 N NE2 . GLN B 1 260 ? 56.024  53.089 47.443  1.00 0.53 ? 260 GLN B NE2 1 
ATOM 5170 N N   . LYS B 1 261 ? 53.418  48.480 46.296  1.00 0.53 ? 261 LYS B N   1 
ATOM 5171 C CA  . LYS B 1 261 ? 52.707  47.536 47.135  1.00 0.53 ? 261 LYS B CA  1 
ATOM 5172 C C   . LYS B 1 261 ? 51.639  46.764 46.364  1.00 0.53 ? 261 LYS B C   1 
ATOM 5173 O O   . LYS B 1 261 ? 50.967  45.902 46.934  1.00 0.53 ? 261 LYS B O   1 
ATOM 5174 C CB  . LYS B 1 261 ? 52.002  48.284 48.295  1.00 0.53 ? 261 LYS B CB  1 
ATOM 5175 C CG  . LYS B 1 261 ? 52.962  48.729 49.413  1.00 0.53 ? 261 LYS B CG  1 
ATOM 5176 C CD  . LYS B 1 261 ? 52.217  49.340 50.617  1.00 0.53 ? 261 LYS B CD  1 
ATOM 5177 C CE  . LYS B 1 261 ? 53.037  49.425 51.915  1.00 0.53 ? 261 LYS B CE  1 
ATOM 5178 N NZ  . LYS B 1 261 ? 54.091  50.456 51.810  1.00 0.53 ? 261 LYS B NZ  1 
ATOM 5179 N N   . ARG B 1 262 ? 51.441  47.047 45.061  1.00 0.53 ? 262 ARG B N   1 
ATOM 5180 C CA  . ARG B 1 262 ? 50.522  46.307 44.210  1.00 0.53 ? 262 ARG B CA  1 
ATOM 5181 C C   . ARG B 1 262 ? 51.194  45.114 43.541  1.00 0.53 ? 262 ARG B C   1 
ATOM 5182 O O   . ARG B 1 262 ? 52.375  45.163 43.219  1.00 0.53 ? 262 ARG B O   1 
ATOM 5183 C CB  . ARG B 1 262 ? 49.975  47.179 43.049  1.00 0.53 ? 262 ARG B CB  1 
ATOM 5184 C CG  . ARG B 1 262 ? 49.294  48.487 43.491  1.00 0.53 ? 262 ARG B CG  1 
ATOM 5185 C CD  . ARG B 1 262 ? 48.697  49.292 42.328  1.00 0.53 ? 262 ARG B CD  1 
ATOM 5186 N NE  . ARG B 1 262 ? 48.250  50.596 42.898  1.00 0.53 ? 262 ARG B NE  1 
ATOM 5187 C CZ  . ARG B 1 262 ? 47.431  51.466 42.298  1.00 0.53 ? 262 ARG B CZ  1 
ATOM 5188 N NH1 . ARG B 1 262 ? 46.962  52.486 43.010  1.00 0.53 ? 262 ARG B NH1 1 
ATOM 5189 N NH2 . ARG B 1 262 ? 47.035  51.371 41.036  1.00 0.53 ? 262 ARG B NH2 1 
ATOM 5190 N N   . THR B 1 263 ? 50.420  44.040 43.257  1.00 0.56 ? 263 THR B N   1 
ATOM 5191 C CA  . THR B 1 263 ? 50.875  42.885 42.480  1.00 0.56 ? 263 THR B CA  1 
ATOM 5192 C C   . THR B 1 263 ? 49.649  42.341 41.779  1.00 0.56 ? 263 THR B C   1 
ATOM 5193 O O   . THR B 1 263 ? 48.633  42.078 42.420  1.00 0.56 ? 263 THR B O   1 
ATOM 5194 C CB  . THR B 1 263 ? 51.519  41.773 43.315  1.00 0.56 ? 263 THR B CB  1 
ATOM 5195 O OG1 . THR B 1 263 ? 52.810  42.182 43.727  1.00 0.56 ? 263 THR B OG1 1 
ATOM 5196 C CG2 . THR B 1 263 ? 51.746  40.462 42.543  1.00 0.56 ? 263 THR B CG2 1 
ATOM 5197 N N   . ALA B 1 264 ? 49.675  42.201 40.434  1.00 0.60 ? 264 ALA B N   1 
ATOM 5198 C CA  . ALA B 1 264 ? 48.550  41.697 39.658  1.00 0.60 ? 264 ALA B CA  1 
ATOM 5199 C C   . ALA B 1 264 ? 48.331  40.182 39.748  1.00 0.60 ? 264 ALA B C   1 
ATOM 5200 O O   . ALA B 1 264 ? 49.261  39.396 39.926  1.00 0.60 ? 264 ALA B O   1 
ATOM 5201 C CB  . ALA B 1 264 ? 48.654  42.148 38.188  1.00 0.60 ? 264 ALA B CB  1 
ATOM 5202 N N   . THR B 1 265 ? 47.063  39.737 39.622  1.00 0.56 ? 265 THR B N   1 
ATOM 5203 C CA  . THR B 1 265 ? 46.637  38.349 39.778  1.00 0.56 ? 265 THR B CA  1 
ATOM 5204 C C   . THR B 1 265 ? 45.448  38.121 38.863  1.00 0.56 ? 265 THR B C   1 
ATOM 5205 O O   . THR B 1 265 ? 44.931  39.051 38.254  1.00 0.56 ? 265 THR B O   1 
ATOM 5206 C CB  . THR B 1 265 ? 46.219  37.943 41.211  1.00 0.56 ? 265 THR B CB  1 
ATOM 5207 O OG1 . THR B 1 265 ? 45.049  38.609 41.669  1.00 0.56 ? 265 THR B OG1 1 
ATOM 5208 C CG2 . THR B 1 265 ? 47.325  38.270 42.222  1.00 0.56 ? 265 THR B CG2 1 
ATOM 5209 N N   . LYS B 1 266 ? 44.938  36.876 38.749  1.00 0.51 ? 266 LYS B N   1 
ATOM 5210 C CA  . LYS B 1 266 ? 43.680  36.581 38.067  1.00 0.51 ? 266 LYS B CA  1 
ATOM 5211 C C   . LYS B 1 266 ? 42.460  37.300 38.670  1.00 0.51 ? 266 LYS B C   1 
ATOM 5212 O O   . LYS B 1 266 ? 41.495  37.611 37.976  1.00 0.51 ? 266 LYS B O   1 
ATOM 5213 C CB  . LYS B 1 266 ? 43.438  35.046 38.045  1.00 0.51 ? 266 LYS B CB  1 
ATOM 5214 C CG  . LYS B 1 266 ? 42.215  34.591 37.222  1.00 0.51 ? 266 LYS B CG  1 
ATOM 5215 C CD  . LYS B 1 266 ? 42.131  33.057 37.090  1.00 0.51 ? 266 LYS B CD  1 
ATOM 5216 C CE  . LYS B 1 266 ? 41.015  32.543 36.171  1.00 0.51 ? 266 LYS B CE  1 
ATOM 5217 N NZ  . LYS B 1 266 ? 39.697  32.794 36.792  1.00 0.51 ? 266 LYS B NZ  1 
ATOM 5218 N N   . ALA B 1 267 ? 42.491  37.580 39.991  1.00 0.52 ? 267 ALA B N   1 
ATOM 5219 C CA  . ALA B 1 267 ? 41.488  38.345 40.701  1.00 0.52 ? 267 ALA B CA  1 
ATOM 5220 C C   . ALA B 1 267 ? 41.683  39.868 40.604  1.00 0.52 ? 267 ALA B C   1 
ATOM 5221 O O   . ALA B 1 267 ? 40.773  40.640 40.900  1.00 0.52 ? 267 ALA B O   1 
ATOM 5222 C CB  . ALA B 1 267 ? 41.535  37.912 42.183  1.00 0.52 ? 267 ALA B CB  1 
ATOM 5223 N N   . TYR B 1 268 ? 42.868  40.347 40.171  1.00 0.46 ? 268 TYR B N   1 
ATOM 5224 C CA  . TYR B 1 268 ? 43.162  41.763 40.068  1.00 0.46 ? 268 TYR B CA  1 
ATOM 5225 C C   . TYR B 1 268 ? 44.093  41.970 38.877  1.00 0.46 ? 268 TYR B C   1 
ATOM 5226 O O   . TYR B 1 268 ? 45.311  41.829 38.972  1.00 0.46 ? 268 TYR B O   1 
ATOM 5227 C CB  . TYR B 1 268 ? 43.784  42.278 41.395  1.00 0.46 ? 268 TYR B CB  1 
ATOM 5228 C CG  . TYR B 1 268 ? 44.128  43.740 41.361  1.00 0.46 ? 268 TYR B CG  1 
ATOM 5229 C CD1 . TYR B 1 268 ? 43.124  44.721 41.347  1.00 0.46 ? 268 TYR B CD1 1 
ATOM 5230 C CD2 . TYR B 1 268 ? 45.473  44.142 41.348  1.00 0.46 ? 268 TYR B CD2 1 
ATOM 5231 C CE1 . TYR B 1 268 ? 43.463  46.080 41.354  1.00 0.46 ? 268 TYR B CE1 1 
ATOM 5232 C CE2 . TYR B 1 268 ? 45.812  45.499 41.328  1.00 0.46 ? 268 TYR B CE2 1 
ATOM 5233 C CZ  . TYR B 1 268 ? 44.804  46.464 41.350  1.00 0.46 ? 268 TYR B CZ  1 
ATOM 5234 O OH  . TYR B 1 268 ? 45.153  47.818 41.423  1.00 0.46 ? 268 TYR B OH  1 
ATOM 5235 N N   . ASN B 1 269 ? 43.522  42.278 37.694  1.00 0.57 ? 269 ASN B N   1 
ATOM 5236 C CA  . ASN B 1 269 ? 44.251  42.378 36.440  1.00 0.57 ? 269 ASN B CA  1 
ATOM 5237 C C   . ASN B 1 269 ? 45.328  43.472 36.365  1.00 0.57 ? 269 ASN B C   1 
ATOM 5238 O O   . ASN B 1 269 ? 45.261  44.497 37.042  1.00 0.57 ? 269 ASN B O   1 
ATOM 5239 C CB  . ASN B 1 269 ? 43.281  42.490 35.229  1.00 0.57 ? 269 ASN B CB  1 
ATOM 5240 C CG  . ASN B 1 269 ? 42.642  41.137 34.927  1.00 0.57 ? 269 ASN B CG  1 
ATOM 5241 O OD1 . ASN B 1 269 ? 43.325  40.179 34.563  1.00 0.57 ? 269 ASN B OD1 1 
ATOM 5242 N ND2 . ASN B 1 269 ? 41.301  41.026 35.029  1.00 0.57 ? 269 ASN B ND2 1 
ATOM 5243 N N   . VAL B 1 270 ? 46.350  43.285 35.487  1.00 0.62 ? 270 VAL B N   1 
ATOM 5244 C CA  . VAL B 1 270 ? 47.443  44.231 35.222  1.00 0.62 ? 270 VAL B CA  1 
ATOM 5245 C C   . VAL B 1 270 ? 46.930  45.609 34.814  1.00 0.62 ? 270 VAL B C   1 
ATOM 5246 O O   . VAL B 1 270 ? 47.461  46.636 35.229  1.00 0.62 ? 270 VAL B O   1 
ATOM 5247 C CB  . VAL B 1 270 ? 48.390  43.686 34.144  1.00 0.62 ? 270 VAL B CB  1 
ATOM 5248 C CG1 . VAL B 1 270 ? 49.477  44.710 33.739  1.00 0.62 ? 270 VAL B CG1 1 
ATOM 5249 C CG2 . VAL B 1 270 ? 49.082  42.405 34.653  1.00 0.62 ? 270 VAL B CG2 1 
ATOM 5250 N N   . THR B 1 271 ? 45.824  45.633 34.046  1.00 0.54 ? 271 THR B N   1 
ATOM 5251 C CA  . THR B 1 271 ? 45.062  46.805 33.631  1.00 0.54 ? 271 THR B CA  1 
ATOM 5252 C C   . THR B 1 271 ? 44.505  47.645 34.774  1.00 0.54 ? 271 THR B C   1 
ATOM 5253 O O   . THR B 1 271 ? 44.314  48.848 34.636  1.00 0.54 ? 271 THR B O   1 
ATOM 5254 C CB  . THR B 1 271 ? 43.892  46.422 32.725  1.00 0.54 ? 271 THR B CB  1 
ATOM 5255 O OG1 . THR B 1 271 ? 43.059  45.420 33.298  1.00 0.54 ? 271 THR B OG1 1 
ATOM 5256 C CG2 . THR B 1 271 ? 44.411  45.822 31.413  1.00 0.54 ? 271 THR B CG2 1 
ATOM 5257 N N   . GLN B 1 272 ? 44.205  47.038 35.944  1.00 0.53 ? 272 GLN B N   1 
ATOM 5258 C CA  . GLN B 1 272 ? 43.771  47.769 37.120  1.00 0.53 ? 272 GLN B CA  1 
ATOM 5259 C C   . GLN B 1 272 ? 44.951  48.307 37.920  1.00 0.53 ? 272 GLN B C   1 
ATOM 5260 O O   . GLN B 1 272 ? 44.904  49.384 38.512  1.00 0.53 ? 272 GLN B O   1 
ATOM 5261 C CB  . GLN B 1 272 ? 42.879  46.880 38.015  1.00 0.53 ? 272 GLN B CB  1 
ATOM 5262 C CG  . GLN B 1 272 ? 41.623  46.358 37.280  1.00 0.53 ? 272 GLN B CG  1 
ATOM 5263 C CD  . GLN B 1 272 ? 40.644  45.686 38.246  1.00 0.53 ? 272 GLN B CD  1 
ATOM 5264 O OE1 . GLN B 1 272 ? 40.599  45.945 39.448  1.00 0.53 ? 272 GLN B OE1 1 
ATOM 5265 N NE2 . GLN B 1 272 ? 39.811  44.766 37.703  1.00 0.53 ? 272 GLN B NE2 1 
ATOM 5266 N N   . ALA B 1 273 ? 46.079  47.567 37.941  1.00 0.57 ? 273 ALA B N   1 
ATOM 5267 C CA  . ALA B 1 273 ? 47.314  48.022 38.545  1.00 0.57 ? 273 ALA B CA  1 
ATOM 5268 C C   . ALA B 1 273 ? 47.932  49.242 37.859  1.00 0.57 ? 273 ALA B C   1 
ATOM 5269 O O   . ALA B 1 273 ? 48.409  50.165 38.533  1.00 0.57 ? 273 ALA B O   1 
ATOM 5270 C CB  . ALA B 1 273 ? 48.335  46.867 38.597  1.00 0.57 ? 273 ALA B CB  1 
ATOM 5271 N N   . PHE B 1 274 ? 47.915  49.250 36.511  1.00 0.50 ? 274 PHE B N   1 
ATOM 5272 C CA  . PHE B 1 274 ? 48.514  50.260 35.667  1.00 0.50 ? 274 PHE B CA  1 
ATOM 5273 C C   . PHE B 1 274 ? 47.651  50.486 34.437  1.00 0.50 ? 274 PHE B C   1 
ATOM 5274 O O   . PHE B 1 274 ? 47.181  49.532 33.823  1.00 0.50 ? 274 PHE B O   1 
ATOM 5275 C CB  . PHE B 1 274 ? 49.882  49.784 35.106  1.00 0.50 ? 274 PHE B CB  1 
ATOM 5276 C CG  . PHE B 1 274 ? 50.843  49.371 36.181  1.00 0.50 ? 274 PHE B CG  1 
ATOM 5277 C CD1 . PHE B 1 274 ? 51.323  50.304 37.109  1.00 0.50 ? 274 PHE B CD1 1 
ATOM 5278 C CD2 . PHE B 1 274 ? 51.309  48.048 36.247  1.00 0.50 ? 274 PHE B CD2 1 
ATOM 5279 C CE1 . PHE B 1 274 ? 52.271  49.932 38.069  1.00 0.50 ? 274 PHE B CE1 1 
ATOM 5280 C CE2 . PHE B 1 274 ? 52.243  47.666 37.216  1.00 0.50 ? 274 PHE B CE2 1 
ATOM 5281 C CZ  . PHE B 1 274 ? 52.729  48.612 38.126  1.00 0.50 ? 274 PHE B CZ  1 
ATOM 5282 N N   . GLY B 1 275 ? 47.456  51.759 34.028  1.00 0.56 ? 275 GLY B N   1 
ATOM 5283 C CA  . GLY B 1 275 ? 46.768  52.096 32.783  1.00 0.56 ? 275 GLY B CA  1 
ATOM 5284 C C   . GLY B 1 275 ? 47.565  51.889 31.521  1.00 0.56 ? 275 GLY B C   1 
ATOM 5285 O O   . GLY B 1 275 ? 48.464  51.052 31.425  1.00 0.56 ? 275 GLY B O   1 
ATOM 5286 N N   . ARG B 1 276 ? 47.237  52.674 30.474  1.00 0.45 ? 276 ARG B N   1 
ATOM 5287 C CA  . ARG B 1 276 ? 47.929  52.615 29.196  1.00 0.45 ? 276 ARG B CA  1 
ATOM 5288 C C   . ARG B 1 276 ? 49.433  52.898 29.297  1.00 0.45 ? 276 ARG B C   1 
ATOM 5289 O O   . ARG B 1 276 ? 49.852  53.949 29.768  1.00 0.45 ? 276 ARG B O   1 
ATOM 5290 C CB  . ARG B 1 276 ? 47.286  53.576 28.160  1.00 0.45 ? 276 ARG B CB  1 
ATOM 5291 C CG  . ARG B 1 276 ? 47.527  53.173 26.689  1.00 0.45 ? 276 ARG B CG  1 
ATOM 5292 C CD  . ARG B 1 276 ? 46.927  54.144 25.657  1.00 0.45 ? 276 ARG B CD  1 
ATOM 5293 N NE  . ARG B 1 276 ? 47.872  55.304 25.476  1.00 0.45 ? 276 ARG B NE  1 
ATOM 5294 C CZ  . ARG B 1 276 ? 48.792  55.429 24.510  1.00 0.45 ? 276 ARG B CZ  1 
ATOM 5295 N NH1 . ARG B 1 276 ? 49.590  56.498 24.486  1.00 0.45 ? 276 ARG B NH1 1 
ATOM 5296 N NH2 . ARG B 1 276 ? 48.918  54.523 23.544  1.00 0.45 ? 276 ARG B NH2 1 
ATOM 5297 N N   . ARG B 1 277 ? 50.280  51.940 28.870  1.00 0.50 ? 277 ARG B N   1 
ATOM 5298 C CA  . ARG B 1 277 ? 51.720  51.992 29.074  1.00 0.50 ? 277 ARG B CA  1 
ATOM 5299 C C   . ARG B 1 277 ? 52.500  52.715 27.977  1.00 0.50 ? 277 ARG B C   1 
ATOM 5300 O O   . ARG B 1 277 ? 51.983  53.032 26.905  1.00 0.50 ? 277 ARG B O   1 
ATOM 5301 C CB  . ARG B 1 277 ? 52.244  50.544 29.268  1.00 0.50 ? 277 ARG B CB  1 
ATOM 5302 C CG  . ARG B 1 277 ? 51.990  50.015 30.697  1.00 0.50 ? 277 ARG B CG  1 
ATOM 5303 C CD  . ARG B 1 277 ? 51.932  48.489 30.849  1.00 0.50 ? 277 ARG B CD  1 
ATOM 5304 N NE  . ARG B 1 277 ? 53.241  47.923 30.376  1.00 0.50 ? 277 ARG B NE  1 
ATOM 5305 C CZ  . ARG B 1 277 ? 53.375  46.919 29.503  1.00 0.50 ? 277 ARG B CZ  1 
ATOM 5306 N NH1 . ARG B 1 277 ? 54.568  46.418 29.185  1.00 0.50 ? 277 ARG B NH1 1 
ATOM 5307 N NH2 . ARG B 1 277 ? 52.325  46.333 28.935  1.00 0.50 ? 277 ARG B NH2 1 
ATOM 5308 N N   . GLY B 1 278 ? 53.799  53.002 28.231  1.00 0.56 ? 278 GLY B N   1 
ATOM 5309 C CA  . GLY B 1 278 ? 54.613  53.792 27.324  1.00 0.56 ? 278 GLY B CA  1 
ATOM 5310 C C   . GLY B 1 278 ? 55.966  54.040 27.940  1.00 0.56 ? 278 GLY B C   1 
ATOM 5311 O O   . GLY B 1 278 ? 56.315  53.361 28.904  1.00 0.56 ? 278 GLY B O   1 
ATOM 5312 N N   . PRO B 1 279 ? 56.759  54.988 27.442  1.00 0.51 ? 279 PRO B N   1 
ATOM 5313 C CA  . PRO B 1 279 ? 58.059  55.336 28.011  1.00 0.51 ? 279 PRO B CA  1 
ATOM 5314 C C   . PRO B 1 279 ? 57.894  56.195 29.263  1.00 0.51 ? 279 PRO B C   1 
ATOM 5315 O O   . PRO B 1 279 ? 58.279  57.363 29.267  1.00 0.51 ? 279 PRO B O   1 
ATOM 5316 C CB  . PRO B 1 279 ? 58.730  56.119 26.858  1.00 0.51 ? 279 PRO B CB  1 
ATOM 5317 C CG  . PRO B 1 279 ? 57.567  56.792 26.123  1.00 0.51 ? 279 PRO B CG  1 
ATOM 5318 C CD  . PRO B 1 279 ? 56.438  55.775 26.251  1.00 0.51 ? 279 PRO B CD  1 
ATOM 5319 N N   . GLU B 1 280 ? 57.331  55.623 30.341  1.00 0.53 ? 280 GLU B N   1 
ATOM 5320 C CA  . GLU B 1 280 ? 56.858  56.350 31.499  1.00 0.53 ? 280 GLU B CA  1 
ATOM 5321 C C   . GLU B 1 280 ? 57.253  55.597 32.756  1.00 0.53 ? 280 GLU B C   1 
ATOM 5322 O O   . GLU B 1 280 ? 57.235  54.372 32.798  1.00 0.53 ? 280 GLU B O   1 
ATOM 5323 C CB  . GLU B 1 280 ? 55.315  56.529 31.442  1.00 0.53 ? 280 GLU B CB  1 
ATOM 5324 C CG  . GLU B 1 280 ? 54.859  57.344 30.201  1.00 0.53 ? 280 GLU B CG  1 
ATOM 5325 C CD  . GLU B 1 280 ? 53.388  57.769 30.198  1.00 0.53 ? 280 GLU B CD  1 
ATOM 5326 O OE1 . GLU B 1 280 ? 52.992  58.511 31.136  1.00 0.53 ? 280 GLU B OE1 1 
ATOM 5327 O OE2 . GLU B 1 280 ? 52.679  57.404 29.222  1.00 0.53 ? 280 GLU B OE2 1 
ATOM 5328 N N   . GLN B 1 281 ? 57.687  56.320 33.811  1.00 0.54 ? 281 GLN B N   1 
ATOM 5329 C CA  . GLN B 1 281 ? 58.274  55.706 34.994  1.00 0.54 ? 281 GLN B CA  1 
ATOM 5330 C C   . GLN B 1 281 ? 57.296  55.138 36.015  1.00 0.54 ? 281 GLN B C   1 
ATOM 5331 O O   . GLN B 1 281 ? 57.624  54.210 36.743  1.00 0.54 ? 281 GLN B O   1 
ATOM 5332 C CB  . GLN B 1 281 ? 59.200  56.732 35.689  1.00 0.54 ? 281 GLN B CB  1 
ATOM 5333 C CG  . GLN B 1 281 ? 60.075  56.168 36.837  1.00 0.54 ? 281 GLN B CG  1 
ATOM 5334 C CD  . GLN B 1 281 ? 61.128  57.198 37.233  1.00 0.54 ? 281 GLN B CD  1 
ATOM 5335 O OE1 . GLN B 1 281 ? 61.071  58.354 36.820  1.00 0.54 ? 281 GLN B OE1 1 
ATOM 5336 N NE2 . GLN B 1 281 ? 62.150  56.784 38.015  1.00 0.54 ? 281 GLN B NE2 1 
ATOM 5337 N N   . THR B 1 282 ? 56.074  55.690 36.129  1.00 0.56 ? 282 THR B N   1 
ATOM 5338 C CA  . THR B 1 282 ? 55.096  55.277 37.141  1.00 0.56 ? 282 THR B CA  1 
ATOM 5339 C C   . THR B 1 282 ? 54.447  53.931 36.880  1.00 0.56 ? 282 THR B C   1 
ATOM 5340 O O   . THR B 1 282 ? 54.205  53.135 37.793  1.00 0.56 ? 282 THR B O   1 
ATOM 5341 C CB  . THR B 1 282 ? 54.013  56.327 37.321  1.00 0.56 ? 282 THR B CB  1 
ATOM 5342 O OG1 . THR B 1 282 ? 54.602  57.544 37.752  1.00 0.56 ? 282 THR B OG1 1 
ATOM 5343 C CG2 . THR B 1 282 ? 52.971  55.969 38.390  1.00 0.56 ? 282 THR B CG2 1 
ATOM 5344 N N   . GLN B 1 283 ? 54.105  53.655 35.613  1.00 0.53 ? 283 GLN B N   1 
ATOM 5345 C CA  . GLN B 1 283 ? 53.491  52.423 35.173  1.00 0.53 ? 283 GLN B CA  1 
ATOM 5346 C C   . GLN B 1 283 ? 54.518  51.320 34.970  1.00 0.53 ? 283 GLN B C   1 
ATOM 5347 O O   . GLN B 1 283 ? 55.661  51.540 34.584  1.00 0.53 ? 283 GLN B O   1 
ATOM 5348 C CB  . GLN B 1 283 ? 52.653  52.622 33.876  1.00 0.53 ? 283 GLN B CB  1 
ATOM 5349 C CG  . GLN B 1 283 ? 51.329  53.416 34.062  1.00 0.53 ? 283 GLN B CG  1 
ATOM 5350 C CD  . GLN B 1 283 ? 51.546  54.879 34.467  1.00 0.53 ? 283 GLN B CD  1 
ATOM 5351 O OE1 . GLN B 1 283 ? 52.562  55.503 34.150  1.00 0.53 ? 283 GLN B OE1 1 
ATOM 5352 N NE2 . GLN B 1 283 ? 50.579  55.439 35.229  1.00 0.53 ? 283 GLN B NE2 1 
ATOM 5353 N N   . GLY B 1 284 ? 54.132  50.061 35.257  1.00 0.59 ? 284 GLY B N   1 
ATOM 5354 C CA  . GLY B 1 284 ? 55.027  48.922 35.106  1.00 0.59 ? 284 GLY B CA  1 
ATOM 5355 C C   . GLY B 1 284 ? 55.535  48.640 33.712  1.00 0.59 ? 284 GLY B C   1 
ATOM 5356 O O   . GLY B 1 284 ? 54.817  48.697 32.713  1.00 0.59 ? 284 GLY B O   1 
ATOM 5357 N N   . ASN B 1 285 ? 56.811  48.214 33.625  1.00 0.58 ? 285 ASN B N   1 
ATOM 5358 C CA  . ASN B 1 285 ? 57.466  47.945 32.357  1.00 0.58 ? 285 ASN B CA  1 
ATOM 5359 C C   . ASN B 1 285 ? 56.970  46.665 31.682  1.00 0.58 ? 285 ASN B C   1 
ATOM 5360 O O   . ASN B 1 285 ? 57.151  46.462 30.483  1.00 0.58 ? 285 ASN B O   1 
ATOM 5361 C CB  . ASN B 1 285 ? 58.994  47.787 32.558  1.00 0.58 ? 285 ASN B CB  1 
ATOM 5362 C CG  . ASN B 1 285 ? 59.609  49.110 32.988  1.00 0.58 ? 285 ASN B CG  1 
ATOM 5363 O OD1 . ASN B 1 285 ? 59.519  50.100 32.270  1.00 0.58 ? 285 ASN B OD1 1 
ATOM 5364 N ND2 . ASN B 1 285 ? 60.284  49.146 34.159  1.00 0.58 ? 285 ASN B ND2 1 
ATOM 5365 N N   . PHE B 1 286 ? 56.308  45.769 32.437  1.00 0.58 ? 286 PHE B N   1 
ATOM 5366 C CA  . PHE B 1 286 ? 56.222  44.356 32.120  1.00 0.58 ? 286 PHE B CA  1 
ATOM 5367 C C   . PHE B 1 286 ? 54.819  43.923 31.680  1.00 0.58 ? 286 PHE B C   1 
ATOM 5368 O O   . PHE B 1 286 ? 53.825  44.224 32.335  1.00 0.58 ? 286 PHE B O   1 
ATOM 5369 C CB  . PHE B 1 286 ? 56.651  43.512 33.359  1.00 0.58 ? 286 PHE B CB  1 
ATOM 5370 C CG  . PHE B 1 286 ? 57.862  44.098 34.047  1.00 0.58 ? 286 PHE B CG  1 
ATOM 5371 C CD1 . PHE B 1 286 ? 59.134  44.021 33.457  1.00 0.58 ? 286 PHE B CD1 1 
ATOM 5372 C CD2 . PHE B 1 286 ? 57.737  44.742 35.290  1.00 0.58 ? 286 PHE B CD2 1 
ATOM 5373 C CE1 . PHE B 1 286 ? 60.254  44.579 34.089  1.00 0.58 ? 286 PHE B CE1 1 
ATOM 5374 C CE2 . PHE B 1 286 ? 58.851  45.306 35.922  1.00 0.58 ? 286 PHE B CE2 1 
ATOM 5375 C CZ  . PHE B 1 286 ? 60.112  45.224 35.322  1.00 0.58 ? 286 PHE B CZ  1 
ATOM 5376 N N   . GLY B 1 287 ? 54.704  43.194 30.541  1.00 0.66 ? 287 GLY B N   1 
ATOM 5377 C CA  . GLY B 1 287 ? 53.438  42.623 30.060  1.00 0.66 ? 287 GLY B CA  1 
ATOM 5378 C C   . GLY B 1 287 ? 53.141  42.986 28.631  1.00 0.66 ? 287 GLY B C   1 
ATOM 5379 O O   . GLY B 1 287 ? 53.618  44.002 28.130  1.00 0.66 ? 287 GLY B O   1 
ATOM 5380 N N   . ASP B 1 288 ? 52.306  42.181 27.944  1.00 0.69 ? 288 ASP B N   1 
ATOM 5381 C CA  . ASP B 1 288 ? 52.020  42.339 26.537  1.00 0.69 ? 288 ASP B CA  1 
ATOM 5382 C C   . ASP B 1 288 ? 50.529  42.073 26.292  1.00 0.69 ? 288 ASP B C   1 
ATOM 5383 O O   . ASP B 1 288 ? 49.841  41.541 27.165  1.00 0.69 ? 288 ASP B O   1 
ATOM 5384 C CB  . ASP B 1 288 ? 52.925  41.383 25.720  1.00 0.69 ? 288 ASP B CB  1 
ATOM 5385 C CG  . ASP B 1 288 ? 52.992  41.835 24.283  1.00 0.69 ? 288 ASP B CG  1 
ATOM 5386 O OD1 . ASP B 1 288 ? 52.455  42.929 23.972  1.00 0.69 ? 288 ASP B OD1 1 
ATOM 5387 O OD2 . ASP B 1 288 ? 53.622  41.117 23.474  1.00 0.69 ? 288 ASP B OD2 1 
ATOM 5388 N N   . GLN B 1 289 ? 49.992  42.448 25.107  1.00 0.69 ? 289 GLN B N   1 
ATOM 5389 C CA  . GLN B 1 289 ? 48.576  42.418 24.739  1.00 0.69 ? 289 GLN B CA  1 
ATOM 5390 C C   . GLN B 1 289 ? 47.946  41.027 24.744  1.00 0.69 ? 289 GLN B C   1 
ATOM 5391 O O   . GLN B 1 289 ? 46.741  40.884 24.952  1.00 0.69 ? 289 GLN B O   1 
ATOM 5392 C CB  . GLN B 1 289 ? 48.309  43.113 23.375  1.00 0.69 ? 289 GLN B CB  1 
ATOM 5393 C CG  . GLN B 1 289 ? 48.459  44.657 23.405  1.00 0.69 ? 289 GLN B CG  1 
ATOM 5394 C CD  . GLN B 1 289 ? 47.220  45.388 23.939  1.00 0.69 ? 289 GLN B CD  1 
ATOM 5395 O OE1 . GLN B 1 289 ? 46.825  45.287 25.103  1.00 0.69 ? 289 GLN B OE1 1 
ATOM 5396 N NE2 . GLN B 1 289 ? 46.575  46.192 23.062  1.00 0.69 ? 289 GLN B NE2 1 
ATOM 5397 N N   . GLU B 1 290 ? 48.738  39.952 24.561  1.00 0.66 ? 290 GLU B N   1 
ATOM 5398 C CA  . GLU B 1 290 ? 48.287  38.579 24.716  1.00 0.66 ? 290 GLU B CA  1 
ATOM 5399 C C   . GLU B 1 290 ? 47.753  38.255 26.109  1.00 0.66 ? 290 GLU B C   1 
ATOM 5400 O O   . GLU B 1 290 ? 46.693  37.643 26.254  1.00 0.66 ? 290 GLU B O   1 
ATOM 5401 C CB  . GLU B 1 290 ? 49.450  37.623 24.404  1.00 0.66 ? 290 GLU B CB  1 
ATOM 5402 C CG  . GLU B 1 290 ? 49.871  37.619 22.921  1.00 0.66 ? 290 GLU B CG  1 
ATOM 5403 C CD  . GLU B 1 290 ? 50.983  36.592 22.739  1.00 0.66 ? 290 GLU B CD  1 
ATOM 5404 O OE1 . GLU B 1 290 ? 52.088  36.775 23.307  1.00 0.66 ? 290 GLU B OE1 1 
ATOM 5405 O OE2 . GLU B 1 290 ? 50.680  35.553 22.098  1.00 0.66 ? 290 GLU B OE2 1 
ATOM 5406 N N   . LEU B 1 291 ? 48.458  38.723 27.165  1.00 0.65 ? 291 LEU B N   1 
ATOM 5407 C CA  . LEU B 1 291 ? 48.014  38.683 28.549  1.00 0.65 ? 291 LEU B CA  1 
ATOM 5408 C C   . LEU B 1 291 ? 46.797  39.550 28.776  1.00 0.65 ? 291 LEU B C   1 
ATOM 5409 O O   . LEU B 1 291 ? 45.848  39.148 29.438  1.00 0.65 ? 291 LEU B O   1 
ATOM 5410 C CB  . LEU B 1 291 ? 49.164  39.093 29.510  1.00 0.65 ? 291 LEU B CB  1 
ATOM 5411 C CG  . LEU B 1 291 ? 48.842  39.076 31.028  1.00 0.65 ? 291 LEU B CG  1 
ATOM 5412 C CD1 . LEU B 1 291 ? 50.097  38.723 31.837  1.00 0.65 ? 291 LEU B CD1 1 
ATOM 5413 C CD2 . LEU B 1 291 ? 48.273  40.404 31.568  1.00 0.65 ? 291 LEU B CD2 1 
ATOM 5414 N N   . ILE B 1 292 ? 46.763  40.767 28.198  1.00 0.60 ? 292 ILE B N   1 
ATOM 5415 C CA  . ILE B 1 292 ? 45.637  41.684 28.332  1.00 0.60 ? 292 ILE B CA  1 
ATOM 5416 C C   . ILE B 1 292 ? 44.348  41.097 27.755  1.00 0.60 ? 292 ILE B C   1 
ATOM 5417 O O   . ILE B 1 292 ? 43.269  41.226 28.327  1.00 0.60 ? 292 ILE B O   1 
ATOM 5418 C CB  . ILE B 1 292 ? 45.952  43.052 27.726  1.00 0.60 ? 292 ILE B CB  1 
ATOM 5419 C CG1 . ILE B 1 292 ? 47.302  43.635 28.233  1.00 0.60 ? 292 ILE B CG1 1 
ATOM 5420 C CG2 . ILE B 1 292 ? 44.803  44.052 27.980  1.00 0.60 ? 292 ILE B CG2 1 
ATOM 5421 C CD1 . ILE B 1 292 ? 47.389  43.898 29.742  1.00 0.60 ? 292 ILE B CD1 1 
ATOM 5422 N N   . ARG B 1 293 ? 44.438  40.393 26.608  1.00 0.48 ? 293 ARG B N   1 
ATOM 5423 C CA  . ARG B 1 293 ? 43.337  39.642 26.034  1.00 0.48 ? 293 ARG B CA  1 
ATOM 5424 C C   . ARG B 1 293 ? 42.871  38.403 26.792  1.00 0.48 ? 293 ARG B C   1 
ATOM 5425 O O   . ARG B 1 293 ? 41.668  38.159 26.869  1.00 0.48 ? 293 ARG B O   1 
ATOM 5426 C CB  . ARG B 1 293 ? 43.689  39.211 24.593  1.00 0.48 ? 293 ARG B CB  1 
ATOM 5427 C CG  . ARG B 1 293 ? 43.584  40.342 23.551  1.00 0.48 ? 293 ARG B CG  1 
ATOM 5428 C CD  . ARG B 1 293 ? 42.202  40.476 22.888  1.00 0.48 ? 293 ARG B CD  1 
ATOM 5429 N NE  . ARG B 1 293 ? 41.201  40.999 23.884  1.00 0.48 ? 293 ARG B NE  1 
ATOM 5430 C CZ  . ARG B 1 293 ? 40.857  42.286 24.030  1.00 0.48 ? 293 ARG B CZ  1 
ATOM 5431 N NH1 . ARG B 1 293 ? 39.882  42.635 24.867  1.00 0.48 ? 293 ARG B NH1 1 
ATOM 5432 N NH2 . ARG B 1 293 ? 41.456  43.262 23.362  1.00 0.48 ? 293 ARG B NH2 1 
ATOM 5433 N N   . GLN B 1 294 ? 43.791  37.570 27.326  1.00 0.47 ? 294 GLN B N   1 
ATOM 5434 C CA  . GLN B 1 294 ? 43.433  36.381 28.093  1.00 0.47 ? 294 GLN B CA  1 
ATOM 5435 C C   . GLN B 1 294 ? 43.010  36.695 29.528  1.00 0.47 ? 294 GLN B C   1 
ATOM 5436 O O   . GLN B 1 294 ? 42.323  35.917 30.189  1.00 0.47 ? 294 GLN B O   1 
ATOM 5437 C CB  . GLN B 1 294 ? 44.649  35.405 28.116  1.00 0.47 ? 294 GLN B CB  1 
ATOM 5438 C CG  . GLN B 1 294 ? 44.506  34.111 28.969  1.00 0.47 ? 294 GLN B CG  1 
ATOM 5439 C CD  . GLN B 1 294 ? 43.324  33.227 28.567  1.00 0.47 ? 294 GLN B CD  1 
ATOM 5440 O OE1 . GLN B 1 294 ? 42.822  33.263 27.435  1.00 0.47 ? 294 GLN B OE1 1 
ATOM 5441 N NE2 . GLN B 1 294 ? 42.876  32.371 29.513  1.00 0.47 ? 294 GLN B NE2 1 
ATOM 5442 N N   . GLY B 1 295 ? 43.403  37.873 30.042  1.00 0.55 ? 295 GLY B N   1 
ATOM 5443 C CA  . GLY B 1 295 ? 43.414  38.178 31.462  1.00 0.55 ? 295 GLY B CA  1 
ATOM 5444 C C   . GLY B 1 295 ? 44.657  37.642 32.126  1.00 0.55 ? 295 GLY B C   1 
ATOM 5445 O O   . GLY B 1 295 ? 45.434  36.870 31.562  1.00 0.55 ? 295 GLY B O   1 
ATOM 5446 N N   . THR B 1 296 ? 44.877  38.017 33.399  1.00 0.56 ? 296 THR B N   1 
ATOM 5447 C CA  . THR B 1 296 ? 46.132  37.748 34.114  1.00 0.56 ? 296 THR B CA  1 
ATOM 5448 C C   . THR B 1 296 ? 46.255  36.294 34.606  1.00 0.56 ? 296 THR B C   1 
ATOM 5449 O O   . THR B 1 296 ? 47.227  35.879 35.229  1.00 0.56 ? 296 THR B O   1 
ATOM 5450 C CB  . THR B 1 296 ? 46.299  38.735 35.268  1.00 0.56 ? 296 THR B CB  1 
ATOM 5451 O OG1 . THR B 1 296 ? 46.222  40.079 34.833  1.00 0.56 ? 296 THR B OG1 1 
ATOM 5452 C CG2 . THR B 1 296 ? 47.651  38.702 35.978  1.00 0.56 ? 296 THR B CG2 1 
ATOM 5453 N N   . ASP B 1 297 ? 45.285  35.439 34.220  1.00 0.54 ? 297 ASP B N   1 
ATOM 5454 C CA  . ASP B 1 297 ? 45.341  33.987 34.151  1.00 0.54 ? 297 ASP B CA  1 
ATOM 5455 C C   . ASP B 1 297 ? 46.496  33.510 33.264  1.00 0.54 ? 297 ASP B C   1 
ATOM 5456 O O   . ASP B 1 297 ? 47.111  32.482 33.536  1.00 0.54 ? 297 ASP B O   1 
ATOM 5457 C CB  . ASP B 1 297 ? 43.962  33.551 33.578  1.00 0.54 ? 297 ASP B CB  1 
ATOM 5458 C CG  . ASP B 1 297 ? 43.803  32.057 33.341  1.00 0.54 ? 297 ASP B CG  1 
ATOM 5459 O OD1 . ASP B 1 297 ? 43.683  31.322 34.353  1.00 0.54 ? 297 ASP B OD1 1 
ATOM 5460 O OD2 . ASP B 1 297 ? 43.708  31.669 32.144  1.00 0.54 ? 297 ASP B OD2 1 
ATOM 5461 N N   . TYR B 1 298 ? 46.804  34.268 32.181  1.00 0.56 ? 298 TYR B N   1 
ATOM 5462 C CA  . TYR B 1 298 ? 47.836  33.985 31.198  1.00 0.56 ? 298 TYR B CA  1 
ATOM 5463 C C   . TYR B 1 298 ? 49.110  33.293 31.703  1.00 0.56 ? 298 TYR B C   1 
ATOM 5464 O O   . TYR B 1 298 ? 49.846  33.816 32.540  1.00 0.56 ? 298 TYR B O   1 
ATOM 5465 C CB  . TYR B 1 298 ? 48.160  35.287 30.417  1.00 0.56 ? 298 TYR B CB  1 
ATOM 5466 C CG  . TYR B 1 298 ? 49.059  35.087 29.227  1.00 0.56 ? 298 TYR B CG  1 
ATOM 5467 C CD1 . TYR B 1 298 ? 48.568  34.562 28.021  1.00 0.56 ? 298 TYR B CD1 1 
ATOM 5468 C CD2 . TYR B 1 298 ? 50.410  35.459 29.306  1.00 0.56 ? 298 TYR B CD2 1 
ATOM 5469 C CE1 . TYR B 1 298 ? 49.420  34.396 26.921  1.00 0.56 ? 298 TYR B CE1 1 
ATOM 5470 C CE2 . TYR B 1 298 ? 51.257  35.308 28.202  1.00 0.56 ? 298 TYR B CE2 1 
ATOM 5471 C CZ  . TYR B 1 298 ? 50.767  34.747 27.020  1.00 0.56 ? 298 TYR B CZ  1 
ATOM 5472 O OH  . TYR B 1 298 ? 51.618  34.505 25.929  1.00 0.56 ? 298 TYR B OH  1 
ATOM 5473 N N   . LYS B 1 299 ? 49.421  32.104 31.132  1.00 0.64 ? 299 LYS B N   1 
ATOM 5474 C CA  . LYS B 1 299 ? 50.420  31.163 31.635  1.00 0.64 ? 299 LYS B CA  1 
ATOM 5475 C C   . LYS B 1 299 ? 51.811  31.707 31.960  1.00 0.64 ? 299 LYS B C   1 
ATOM 5476 O O   . LYS B 1 299 ? 52.487  31.216 32.861  1.00 0.64 ? 299 LYS B O   1 
ATOM 5477 C CB  . LYS B 1 299 ? 50.580  29.954 30.670  1.00 0.64 ? 299 LYS B CB  1 
ATOM 5478 C CG  . LYS B 1 299 ? 49.582  28.817 30.947  1.00 0.64 ? 299 LYS B CG  1 
ATOM 5479 C CD  . LYS B 1 299 ? 49.855  27.585 30.066  1.00 0.64 ? 299 LYS B CD  1 
ATOM 5480 C CE  . LYS B 1 299 ? 49.069  26.338 30.491  1.00 0.64 ? 299 LYS B CE  1 
ATOM 5481 N NZ  . LYS B 1 299 ? 49.405  25.199 29.608  1.00 0.64 ? 299 LYS B NZ  1 
ATOM 5482 N N   . HIS B 1 300 ? 52.288  32.737 31.240  1.00 0.67 ? 300 HIS B N   1 
ATOM 5483 C CA  . HIS B 1 300 ? 53.590  33.332 31.502  1.00 0.67 ? 300 HIS B CA  1 
ATOM 5484 C C   . HIS B 1 300 ? 53.640  34.234 32.731  1.00 0.67 ? 300 HIS B C   1 
ATOM 5485 O O   . HIS B 1 300 ? 54.724  34.525 33.235  1.00 0.67 ? 300 HIS B O   1 
ATOM 5486 C CB  . HIS B 1 300 ? 54.079  34.172 30.309  1.00 0.67 ? 300 HIS B CB  1 
ATOM 5487 C CG  . HIS B 1 300 ? 54.207  33.394 29.040  1.00 0.67 ? 300 HIS B CG  1 
ATOM 5488 N ND1 . HIS B 1 300 ? 54.462  34.088 27.876  1.00 0.67 ? 300 HIS B ND1 1 
ATOM 5489 C CD2 . HIS B 1 300 ? 54.130  32.060 28.792  1.00 0.67 ? 300 HIS B CD2 1 
ATOM 5490 C CE1 . HIS B 1 300 ? 54.529  33.162 26.940  1.00 0.67 ? 300 HIS B CE1 1 
ATOM 5491 N NE2 . HIS B 1 300 ? 54.337  31.918 27.439  1.00 0.67 ? 300 HIS B NE2 1 
ATOM 5492 N N   . TRP B 1 301 ? 52.486  34.697 33.264  1.00 0.57 ? 301 TRP B N   1 
ATOM 5493 C CA  . TRP B 1 301 ? 52.446  35.688 34.332  1.00 0.57 ? 301 TRP B CA  1 
ATOM 5494 C C   . TRP B 1 301 ? 53.183  35.322 35.628  1.00 0.57 ? 301 TRP B C   1 
ATOM 5495 O O   . TRP B 1 301 ? 53.883  36.208 36.118  1.00 0.57 ? 301 TRP B O   1 
ATOM 5496 C CB  . TRP B 1 301 ? 51.001  36.187 34.633  1.00 0.57 ? 301 TRP B CB  1 
ATOM 5497 C CG  . TRP B 1 301 ? 50.907  37.250 35.730  1.00 0.57 ? 301 TRP B CG  1 
ATOM 5498 C CD1 . TRP B 1 301 ? 50.438  37.083 37.005  1.00 0.57 ? 301 TRP B CD1 1 
ATOM 5499 C CD2 . TRP B 1 301 ? 51.472  38.576 35.683  1.00 0.57 ? 301 TRP B CD2 1 
ATOM 5500 N NE1 . TRP B 1 301 ? 50.659  38.221 37.746  1.00 0.57 ? 301 TRP B NE1 1 
ATOM 5501 C CE2 . TRP B 1 301 ? 51.310  39.135 36.966  1.00 0.57 ? 301 TRP B CE2 1 
ATOM 5502 C CE3 . TRP B 1 301 ? 52.106  39.294 34.674  1.00 0.57 ? 301 TRP B CE3 1 
ATOM 5503 C CZ2 . TRP B 1 301 ? 51.788  40.401 37.262  1.00 0.57 ? 301 TRP B CZ2 1 
ATOM 5504 C CZ3 . TRP B 1 301 ? 52.561  40.590 34.964  1.00 0.57 ? 301 TRP B CZ3 1 
ATOM 5505 C CH2 . TRP B 1 301 ? 52.413  41.135 36.246  1.00 0.57 ? 301 TRP B CH2 1 
ATOM 5506 N N   . PRO B 1 302 ? 53.169  34.127 36.228  1.00 0.63 ? 302 PRO B N   1 
ATOM 5507 C CA  . PRO B 1 302 ? 53.963  33.827 37.419  1.00 0.63 ? 302 PRO B CA  1 
ATOM 5508 C C   . PRO B 1 302 ? 55.463  34.041 37.255  1.00 0.63 ? 302 PRO B C   1 
ATOM 5509 O O   . PRO B 1 302 ? 56.145  34.281 38.249  1.00 0.63 ? 302 PRO B O   1 
ATOM 5510 C CB  . PRO B 1 302 ? 53.606  32.366 37.750  1.00 0.63 ? 302 PRO B CB  1 
ATOM 5511 C CG  . PRO B 1 302 ? 52.196  32.192 37.182  1.00 0.63 ? 302 PRO B CG  1 
ATOM 5512 C CD  . PRO B 1 302 ? 52.238  33.039 35.913  1.00 0.63 ? 302 PRO B CD  1 
ATOM 5513 N N   . GLN B 1 303 ? 55.999  33.935 36.022  1.00 0.66 ? 303 GLN B N   1 
ATOM 5514 C CA  . GLN B 1 303 ? 57.374  34.274 35.714  1.00 0.66 ? 303 GLN B CA  1 
ATOM 5515 C C   . GLN B 1 303 ? 57.581  35.771 35.497  1.00 0.66 ? 303 GLN B C   1 
ATOM 5516 O O   . GLN B 1 303 ? 58.519  36.357 36.035  1.00 0.66 ? 303 GLN B O   1 
ATOM 5517 C CB  . GLN B 1 303 ? 57.884  33.465 34.504  1.00 0.66 ? 303 GLN B CB  1 
ATOM 5518 C CG  . GLN B 1 303 ? 57.787  31.939 34.747  1.00 0.66 ? 303 GLN B CG  1 
ATOM 5519 C CD  . GLN B 1 303 ? 58.899  31.183 34.012  1.00 0.66 ? 303 GLN B CD  1 
ATOM 5520 O OE1 . GLN B 1 303 ? 60.072  31.533 34.151  1.00 0.66 ? 303 GLN B OE1 1 
ATOM 5521 N NE2 . GLN B 1 303 ? 58.541  30.118 33.260  1.00 0.66 ? 303 GLN B NE2 1 
ATOM 5522 N N   . ILE B 1 304 ? 56.671  36.443 34.752  1.00 0.63 ? 304 ILE B N   1 
ATOM 5523 C CA  . ILE B 1 304 ? 56.705  37.885 34.484  1.00 0.63 ? 304 ILE B CA  1 
ATOM 5524 C C   . ILE B 1 304 ? 56.599  38.714 35.759  1.00 0.63 ? 304 ILE B C   1 
ATOM 5525 O O   . ILE B 1 304 ? 57.277  39.727 35.937  1.00 0.63 ? 304 ILE B O   1 
ATOM 5526 C CB  . ILE B 1 304 ? 55.594  38.323 33.522  1.00 0.63 ? 304 ILE B CB  1 
ATOM 5527 C CG1 . ILE B 1 304 ? 55.686  37.580 32.169  1.00 0.63 ? 304 ILE B CG1 1 
ATOM 5528 C CG2 . ILE B 1 304 ? 55.639  39.855 33.278  1.00 0.63 ? 304 ILE B CG2 1 
ATOM 5529 C CD1 . ILE B 1 304 ? 54.410  37.711 31.325  1.00 0.63 ? 304 ILE B CD1 1 
ATOM 5530 N N   . ALA B 1 305 ? 55.754  38.267 36.707  1.00 0.63 ? 305 ALA B N   1 
ATOM 5531 C CA  . ALA B 1 305 ? 55.514  38.886 37.992  1.00 0.63 ? 305 ALA B CA  1 
ATOM 5532 C C   . ALA B 1 305 ? 56.745  39.007 38.886  1.00 0.63 ? 305 ALA B C   1 
ATOM 5533 O O   . ALA B 1 305 ? 56.779  39.835 39.790  1.00 0.63 ? 305 ALA B O   1 
ATOM 5534 C CB  . ALA B 1 305 ? 54.423  38.081 38.726  1.00 0.63 ? 305 ALA B CB  1 
ATOM 5535 N N   . GLN B 1 306 ? 57.800  38.204 38.634  1.00 0.59 ? 306 GLN B N   1 
ATOM 5536 C CA  . GLN B 1 306 ? 59.052  38.277 39.359  1.00 0.59 ? 306 GLN B CA  1 
ATOM 5537 C C   . GLN B 1 306 ? 59.876  39.512 39.018  1.00 0.59 ? 306 GLN B C   1 
ATOM 5538 O O   . GLN B 1 306 ? 60.680  39.971 39.821  1.00 0.59 ? 306 GLN B O   1 
ATOM 5539 C CB  . GLN B 1 306 ? 59.928  37.030 39.069  1.00 0.59 ? 306 GLN B CB  1 
ATOM 5540 C CG  . GLN B 1 306 ? 59.222  35.669 39.277  1.00 0.59 ? 306 GLN B CG  1 
ATOM 5541 C CD  . GLN B 1 306 ? 58.613  35.536 40.672  1.00 0.59 ? 306 GLN B CD  1 
ATOM 5542 O OE1 . GLN B 1 306 ? 59.187  35.934 41.684  1.00 0.59 ? 306 GLN B OE1 1 
ATOM 5543 N NE2 . GLN B 1 306 ? 57.402  34.936 40.735  1.00 0.59 ? 306 GLN B NE2 1 
ATOM 5544 N N   . PHE B 1 307 ? 59.700  40.088 37.805  1.00 0.52 ? 307 PHE B N   1 
ATOM 5545 C CA  . PHE B 1 307 ? 60.500  41.203 37.320  1.00 0.52 ? 307 PHE B CA  1 
ATOM 5546 C C   . PHE B 1 307 ? 60.365  42.466 38.163  1.00 0.52 ? 307 PHE B C   1 
ATOM 5547 O O   . PHE B 1 307 ? 61.326  43.216 38.345  1.00 0.52 ? 307 PHE B O   1 
ATOM 5548 C CB  . PHE B 1 307 ? 60.202  41.530 35.833  1.00 0.52 ? 307 PHE B CB  1 
ATOM 5549 C CG  . PHE B 1 307 ? 60.407  40.377 34.877  1.00 0.52 ? 307 PHE B CG  1 
ATOM 5550 C CD1 . PHE B 1 307 ? 61.357  39.359 35.085  1.00 0.52 ? 307 PHE B CD1 1 
ATOM 5551 C CD2 . PHE B 1 307 ? 59.643  40.344 33.697  1.00 0.52 ? 307 PHE B CD2 1 
ATOM 5552 C CE1 . PHE B 1 307 ? 61.515  38.328 34.152  1.00 0.52 ? 307 PHE B CE1 1 
ATOM 5553 C CE2 . PHE B 1 307 ? 59.804  39.318 32.758  1.00 0.52 ? 307 PHE B CE2 1 
ATOM 5554 C CZ  . PHE B 1 307 ? 60.737  38.303 32.991  1.00 0.52 ? 307 PHE B CZ  1 
ATOM 5555 N N   . ALA B 1 308 ? 59.161  42.717 38.710  1.00 0.55 ? 308 ALA B N   1 
ATOM 5556 C CA  . ALA B 1 308 ? 58.926  43.741 39.701  1.00 0.55 ? 308 ALA B CA  1 
ATOM 5557 C C   . ALA B 1 308 ? 59.067  43.144 41.113  1.00 0.55 ? 308 ALA B C   1 
ATOM 5558 O O   . ALA B 1 308 ? 58.369  42.180 41.418  1.00 0.55 ? 308 ALA B O   1 
ATOM 5559 C CB  . ALA B 1 308 ? 57.506  44.317 39.525  1.00 0.55 ? 308 ALA B CB  1 
ATOM 5560 N N   . PRO B 1 309 ? 59.922  43.619 42.016  1.00 0.51 ? 309 PRO B N   1 
ATOM 5561 C CA  . PRO B 1 309 ? 60.032  43.068 43.362  1.00 0.51 ? 309 PRO B CA  1 
ATOM 5562 C C   . PRO B 1 309 ? 58.873  43.426 44.270  1.00 0.51 ? 309 PRO B C   1 
ATOM 5563 O O   . PRO B 1 309 ? 58.258  44.479 44.119  1.00 0.51 ? 309 PRO B O   1 
ATOM 5564 C CB  . PRO B 1 309 ? 61.313  43.709 43.920  1.00 0.51 ? 309 PRO B CB  1 
ATOM 5565 C CG  . PRO B 1 309 ? 61.417  45.041 43.173  1.00 0.51 ? 309 PRO B CG  1 
ATOM 5566 C CD  . PRO B 1 309 ? 60.829  44.738 41.798  1.00 0.51 ? 309 PRO B CD  1 
ATOM 5567 N N   . SER B 1 310 ? 58.604  42.568 45.280  1.00 0.52 ? 310 SER B N   1 
ATOM 5568 C CA  . SER B 1 310 ? 57.812  42.925 46.454  1.00 0.52 ? 310 SER B CA  1 
ATOM 5569 C C   . SER B 1 310 ? 58.522  43.980 47.290  1.00 0.52 ? 310 SER B C   1 
ATOM 5570 O O   . SER B 1 310 ? 59.751  44.062 47.295  1.00 0.52 ? 310 SER B O   1 
ATOM 5571 C CB  . SER B 1 310 ? 57.474  41.694 47.342  1.00 0.52 ? 310 SER B CB  1 
ATOM 5572 O OG  . SER B 1 310 ? 56.607  42.019 48.436  1.00 0.52 ? 310 SER B OG  1 
ATOM 5573 N N   . ALA B 1 311 ? 57.765  44.809 48.035  1.00 0.55 ? 311 ALA B N   1 
ATOM 5574 C CA  . ALA B 1 311 ? 58.241  45.953 48.792  1.00 0.55 ? 311 ALA B CA  1 
ATOM 5575 C C   . ALA B 1 311 ? 59.337  45.651 49.821  1.00 0.55 ? 311 ALA B C   1 
ATOM 5576 O O   . ALA B 1 311 ? 60.222  46.470 50.055  1.00 0.55 ? 311 ALA B O   1 
ATOM 5577 C CB  . ALA B 1 311 ? 57.040  46.657 49.462  1.00 0.55 ? 311 ALA B CB  1 
ATOM 5578 N N   . SER B 1 312 ? 59.313  44.450 50.433  1.00 0.45 ? 312 SER B N   1 
ATOM 5579 C CA  . SER B 1 312 ? 60.351  43.933 51.315  1.00 0.45 ? 312 SER B CA  1 
ATOM 5580 C C   . SER B 1 312 ? 61.695  43.714 50.623  1.00 0.45 ? 312 SER B C   1 
ATOM 5581 O O   . SER B 1 312 ? 62.751  43.987 51.188  1.00 0.45 ? 312 SER B O   1 
ATOM 5582 C CB  . SER B 1 312 ? 59.892  42.617 52.001  1.00 0.45 ? 312 SER B CB  1 
ATOM 5583 O OG  . SER B 1 312 ? 59.479  41.635 51.042  1.00 0.45 ? 312 SER B OG  1 
ATOM 5584 N N   . ALA B 1 313 ? 61.690  43.234 49.362  1.00 0.50 ? 313 ALA B N   1 
ATOM 5585 C CA  . ALA B 1 313 ? 62.888  42.966 48.592  1.00 0.50 ? 313 ALA B CA  1 
ATOM 5586 C C   . ALA B 1 313 ? 63.348  44.157 47.753  1.00 0.50 ? 313 ALA B C   1 
ATOM 5587 O O   . ALA B 1 313 ? 64.478  44.197 47.271  1.00 0.50 ? 313 ALA B O   1 
ATOM 5588 C CB  . ALA B 1 313 ? 62.583  41.806 47.624  1.00 0.50 ? 313 ALA B CB  1 
ATOM 5589 N N   . PHE B 1 314 ? 62.478  45.172 47.578  1.00 0.41 ? 314 PHE B N   1 
ATOM 5590 C CA  . PHE B 1 314 ? 62.633  46.288 46.658  1.00 0.41 ? 314 PHE B CA  1 
ATOM 5591 C C   . PHE B 1 314 ? 63.887  47.127 46.874  1.00 0.41 ? 314 PHE B C   1 
ATOM 5592 O O   . PHE B 1 314 ? 64.603  47.436 45.926  1.00 0.41 ? 314 PHE B O   1 
ATOM 5593 C CB  . PHE B 1 314 ? 61.333  47.140 46.735  1.00 0.41 ? 314 PHE B CB  1 
ATOM 5594 C CG  . PHE B 1 314 ? 61.173  48.280 45.756  1.00 0.41 ? 314 PHE B CG  1 
ATOM 5595 C CD1 . PHE B 1 314 ? 61.813  48.347 44.505  1.00 0.41 ? 314 PHE B CD1 1 
ATOM 5596 C CD2 . PHE B 1 314 ? 60.274  49.304 46.099  1.00 0.41 ? 314 PHE B CD2 1 
ATOM 5597 C CE1 . PHE B 1 314 ? 61.547  49.401 43.620  1.00 0.41 ? 314 PHE B CE1 1 
ATOM 5598 C CE2 . PHE B 1 314 ? 60.026  50.371 45.230  1.00 0.41 ? 314 PHE B CE2 1 
ATOM 5599 C CZ  . PHE B 1 314 ? 60.652  50.408 43.983  1.00 0.41 ? 314 PHE B CZ  1 
ATOM 5600 N N   . PHE B 1 315 ? 64.227  47.439 48.140  1.00 0.36 ? 315 PHE B N   1 
ATOM 5601 C CA  . PHE B 1 315 ? 65.418  48.178 48.533  1.00 0.36 ? 315 PHE B CA  1 
ATOM 5602 C C   . PHE B 1 315 ? 66.722  47.443 48.190  1.00 0.36 ? 315 PHE B C   1 
ATOM 5603 O O   . PHE B 1 315 ? 67.764  48.046 47.953  1.00 0.36 ? 315 PHE B O   1 
ATOM 5604 C CB  . PHE B 1 315 ? 65.291  48.503 50.047  1.00 0.36 ? 315 PHE B CB  1 
ATOM 5605 C CG  . PHE B 1 315 ? 66.354  49.440 50.550  1.00 0.36 ? 315 PHE B CG  1 
ATOM 5606 C CD1 . PHE B 1 315 ? 66.358  50.793 50.177  1.00 0.36 ? 315 PHE B CD1 1 
ATOM 5607 C CD2 . PHE B 1 315 ? 67.352  48.972 51.416  1.00 0.36 ? 315 PHE B CD2 1 
ATOM 5608 C CE1 . PHE B 1 315 ? 67.336  51.666 50.672  1.00 0.36 ? 315 PHE B CE1 1 
ATOM 5609 C CE2 . PHE B 1 315 ? 68.334  49.840 51.907  1.00 0.36 ? 315 PHE B CE2 1 
ATOM 5610 C CZ  . PHE B 1 315 ? 68.324  51.189 51.539  1.00 0.36 ? 315 PHE B CZ  1 
ATOM 5611 N N   . GLY B 1 316 ? 66.696  46.092 48.113  1.00 0.46 ? 316 GLY B N   1 
ATOM 5612 C CA  . GLY B 1 316 ? 67.853  45.315 47.681  1.00 0.46 ? 316 GLY B CA  1 
ATOM 5613 C C   . GLY B 1 316 ? 68.011  45.190 46.188  1.00 0.46 ? 316 GLY B C   1 
ATOM 5614 O O   . GLY B 1 316 ? 69.016  44.653 45.714  1.00 0.46 ? 316 GLY B O   1 
ATOM 5615 N N   . MET B 1 317 ? 67.009  45.660 45.417  1.00 0.39 ? 317 MET B N   1 
ATOM 5616 C CA  . MET B 1 317 ? 66.974  45.563 43.973  1.00 0.39 ? 317 MET B CA  1 
ATOM 5617 C C   . MET B 1 317 ? 67.015  46.923 43.290  1.00 0.39 ? 317 MET B C   1 
ATOM 5618 O O   . MET B 1 317 ? 67.384  47.011 42.124  1.00 0.39 ? 317 MET B O   1 
ATOM 5619 C CB  . MET B 1 317 ? 65.678  44.827 43.539  1.00 0.39 ? 317 MET B CB  1 
ATOM 5620 C CG  . MET B 1 317 ? 65.583  43.373 44.047  1.00 0.39 ? 317 MET B CG  1 
ATOM 5621 S SD  . MET B 1 317 ? 66.871  42.297 43.361  1.00 0.39 ? 317 MET B SD  1 
ATOM 5622 C CE  . MET B 1 317 ? 66.311  40.754 44.126  1.00 0.39 ? 317 MET B CE  1 
ATOM 5623 N N   . SER B 1 318 ? 66.681  48.020 43.991  1.00 0.43 ? 318 SER B N   1 
ATOM 5624 C CA  . SER B 1 318 ? 66.618  49.335 43.388  1.00 0.43 ? 318 SER B CA  1 
ATOM 5625 C C   . SER B 1 318 ? 66.863  50.378 44.456  1.00 0.43 ? 318 SER B C   1 
ATOM 5626 O O   . SER B 1 318 ? 66.586  50.169 45.634  1.00 0.43 ? 318 SER B O   1 
ATOM 5627 C CB  . SER B 1 318 ? 65.204  49.593 42.800  1.00 0.43 ? 318 SER B CB  1 
ATOM 5628 O OG  . SER B 1 318 ? 65.026  50.883 42.207  1.00 0.43 ? 318 SER B OG  1 
ATOM 5629 N N   . ARG B 1 319 ? 67.381  51.560 44.059  1.00 0.36 ? 319 ARG B N   1 
ATOM 5630 C CA  . ARG B 1 319 ? 67.336  52.768 44.863  1.00 0.36 ? 319 ARG B CA  1 
ATOM 5631 C C   . ARG B 1 319 ? 65.913  53.213 45.183  1.00 0.36 ? 319 ARG B C   1 
ATOM 5632 O O   . ARG B 1 319 ? 65.019  53.091 44.349  1.00 0.36 ? 319 ARG B O   1 
ATOM 5633 C CB  . ARG B 1 319 ? 68.067  53.943 44.156  1.00 0.36 ? 319 ARG B CB  1 
ATOM 5634 C CG  . ARG B 1 319 ? 67.531  54.318 42.749  1.00 0.36 ? 319 ARG B CG  1 
ATOM 5635 C CD  . ARG B 1 319 ? 68.274  55.513 42.143  1.00 0.36 ? 319 ARG B CD  1 
ATOM 5636 N NE  . ARG B 1 319 ? 67.786  55.744 40.742  1.00 0.36 ? 319 ARG B NE  1 
ATOM 5637 C CZ  . ARG B 1 319 ? 68.265  56.713 39.947  1.00 0.36 ? 319 ARG B CZ  1 
ATOM 5638 N NH1 . ARG B 1 319 ? 67.817  56.830 38.698  1.00 0.36 ? 319 ARG B NH1 1 
ATOM 5639 N NH2 . ARG B 1 319 ? 69.150  57.601 40.377  1.00 0.36 ? 319 ARG B NH2 1 
ATOM 5640 N N   . ILE B 1 320 ? 65.668  53.752 46.396  1.00 0.42 ? 320 ILE B N   1 
ATOM 5641 C CA  . ILE B 1 320 ? 64.339  54.185 46.807  1.00 0.42 ? 320 ILE B CA  1 
ATOM 5642 C C   . ILE B 1 320 ? 64.457  55.589 47.370  1.00 0.42 ? 320 ILE B C   1 
ATOM 5643 O O   . ILE B 1 320 ? 65.368  55.895 48.140  1.00 0.42 ? 320 ILE B O   1 
ATOM 5644 C CB  . ILE B 1 320 ? 63.689  53.223 47.812  1.00 0.42 ? 320 ILE B CB  1 
ATOM 5645 C CG1 . ILE B 1 320 ? 63.447  51.846 47.142  1.00 0.42 ? 320 ILE B CG1 1 
ATOM 5646 C CG2 . ILE B 1 320 ? 62.366  53.813 48.365  1.00 0.42 ? 320 ILE B CG2 1 
ATOM 5647 C CD1 . ILE B 1 320 ? 62.776  50.801 48.041  1.00 0.42 ? 320 ILE B CD1 1 
ATOM 5648 N N   . GLY B 1 321 ? 63.542  56.497 46.972  1.00 0.53 ? 321 GLY B N   1 
ATOM 5649 C CA  . GLY B 1 321 ? 63.465  57.845 47.511  1.00 0.53 ? 321 GLY B CA  1 
ATOM 5650 C C   . GLY B 1 321 ? 62.241  58.506 46.940  1.00 0.53 ? 321 GLY B C   1 
ATOM 5651 O O   . GLY B 1 321 ? 61.355  57.811 46.447  1.00 0.53 ? 321 GLY B O   1 
ATOM 5652 N N   . MET B 1 322 ? 62.161  59.853 46.966  1.00 0.43 ? 322 MET B N   1 
ATOM 5653 C CA  . MET B 1 322 ? 61.091  60.582 46.302  1.00 0.43 ? 322 MET B CA  1 
ATOM 5654 C C   . MET B 1 322 ? 61.601  61.863 45.662  1.00 0.43 ? 322 MET B C   1 
ATOM 5655 O O   . MET B 1 322 ? 62.629  62.410 46.062  1.00 0.43 ? 322 MET B O   1 
ATOM 5656 C CB  . MET B 1 322 ? 59.926  60.977 47.254  1.00 0.43 ? 322 MET B CB  1 
ATOM 5657 C CG  . MET B 1 322 ? 59.060  59.786 47.701  1.00 0.43 ? 322 MET B CG  1 
ATOM 5658 S SD  . MET B 1 322 ? 57.370  60.239 48.201  1.00 0.43 ? 322 MET B SD  1 
ATOM 5659 C CE  . MET B 1 322 ? 57.833  61.123 49.714  1.00 0.43 ? 322 MET B CE  1 
ATOM 5660 N N   . GLU B 1 323 ? 60.843  62.378 44.669  1.00 0.48 ? 323 GLU B N   1 
ATOM 5661 C CA  . GLU B 1 323 ? 61.119  63.606 43.952  1.00 0.48 ? 323 GLU B CA  1 
ATOM 5662 C C   . GLU B 1 323 ? 59.837  64.423 43.783  1.00 0.48 ? 323 GLU B C   1 
ATOM 5663 O O   . GLU B 1 323 ? 58.724  63.898 43.806  1.00 0.48 ? 323 GLU B O   1 
ATOM 5664 C CB  . GLU B 1 323 ? 61.761  63.288 42.575  1.00 0.48 ? 323 GLU B CB  1 
ATOM 5665 C CG  . GLU B 1 323 ? 60.883  62.481 41.584  1.00 0.48 ? 323 GLU B CG  1 
ATOM 5666 C CD  . GLU B 1 323 ? 61.727  61.891 40.449  1.00 0.48 ? 323 GLU B CD  1 
ATOM 5667 O OE1 . GLU B 1 323 ? 62.626  61.056 40.753  1.00 0.48 ? 323 GLU B OE1 1 
ATOM 5668 O OE2 . GLU B 1 323 ? 61.488  62.289 39.281  1.00 0.48 ? 323 GLU B OE2 1 
ATOM 5669 N N   . VAL B 1 324 ? 59.950  65.771 43.691  1.00 0.44 ? 324 VAL B N   1 
ATOM 5670 C CA  . VAL B 1 324 ? 58.829  66.686 43.471  1.00 0.44 ? 324 VAL B CA  1 
ATOM 5671 C C   . VAL B 1 324 ? 58.223  66.612 42.061  1.00 0.44 ? 324 VAL B C   1 
ATOM 5672 O O   . VAL B 1 324 ? 58.938  66.520 41.067  1.00 0.44 ? 324 VAL B O   1 
ATOM 5673 C CB  . VAL B 1 324 ? 59.182  68.144 43.811  1.00 0.44 ? 324 VAL B CB  1 
ATOM 5674 C CG1 . VAL B 1 324 ? 59.422  68.286 45.330  1.00 0.44 ? 324 VAL B CG1 1 
ATOM 5675 C CG2 . VAL B 1 324 ? 60.410  68.641 43.016  1.00 0.44 ? 324 VAL B CG2 1 
ATOM 5676 N N   . THR B 1 325 ? 56.874  66.678 41.921  1.00 0.48 ? 325 THR B N   1 
ATOM 5677 C CA  . THR B 1 325 ? 56.213  66.662 40.620  1.00 0.48 ? 325 THR B CA  1 
ATOM 5678 C C   . THR B 1 325 ? 55.037  67.631 40.633  1.00 0.48 ? 325 THR B C   1 
ATOM 5679 O O   . THR B 1 325 ? 54.675  68.139 41.700  1.00 0.48 ? 325 THR B O   1 
ATOM 5680 C CB  . THR B 1 325 ? 55.751  65.292 40.063  1.00 0.48 ? 325 THR B CB  1 
ATOM 5681 O OG1 . THR B 1 325 ? 54.600  64.731 40.670  1.00 0.48 ? 325 THR B OG1 1 
ATOM 5682 C CG2 . THR B 1 325 ? 56.857  64.229 40.089  1.00 0.48 ? 325 THR B CG2 1 
ATOM 5683 N N   . PRO B 1 326 ? 54.388  67.935 39.497  1.00 0.44 ? 326 PRO B N   1 
ATOM 5684 C CA  . PRO B 1 326 ? 53.120  68.655 39.447  1.00 0.44 ? 326 PRO B CA  1 
ATOM 5685 C C   . PRO B 1 326 ? 51.944  67.951 40.089  1.00 0.44 ? 326 PRO B C   1 
ATOM 5686 O O   . PRO B 1 326 ? 50.845  68.487 39.993  1.00 0.44 ? 326 PRO B O   1 
ATOM 5687 C CB  . PRO B 1 326 ? 52.830  68.827 37.952  1.00 0.44 ? 326 PRO B CB  1 
ATOM 5688 C CG  . PRO B 1 326 ? 54.211  68.838 37.305  1.00 0.44 ? 326 PRO B CG  1 
ATOM 5689 C CD  . PRO B 1 326 ? 54.992  67.851 38.163  1.00 0.44 ? 326 PRO B CD  1 
ATOM 5690 N N   . SER B 1 327 ? 52.138  66.743 40.655  1.00 0.47 ? 327 SER B N   1 
ATOM 5691 C CA  . SER B 1 327 ? 51.133  65.993 41.382  1.00 0.47 ? 327 SER B CA  1 
ATOM 5692 C C   . SER B 1 327 ? 51.567  65.794 42.825  1.00 0.47 ? 327 SER B C   1 
ATOM 5693 O O   . SER B 1 327 ? 51.043  64.926 43.516  1.00 0.47 ? 327 SER B O   1 
ATOM 5694 C CB  . SER B 1 327 ? 50.854  64.589 40.791  1.00 0.47 ? 327 SER B CB  1 
ATOM 5695 O OG  . SER B 1 327 ? 50.436  64.669 39.423  1.00 0.47 ? 327 SER B OG  1 
ATOM 5696 N N   . GLY B 1 328 ? 52.541  66.593 43.328  1.00 0.46 ? 328 GLY B N   1 
ATOM 5697 C CA  . GLY B 1 328 ? 53.138  66.412 44.652  1.00 0.46 ? 328 GLY B CA  1 
ATOM 5698 C C   . GLY B 1 328 ? 54.324  65.474 44.634  1.00 0.46 ? 328 GLY B C   1 
ATOM 5699 O O   . GLY B 1 328 ? 54.768  65.026 43.584  1.00 0.46 ? 328 GLY B O   1 
ATOM 5700 N N   . THR B 1 329 ? 54.952  65.182 45.792  1.00 0.46 ? 329 THR B N   1 
ATOM 5701 C CA  . THR B 1 329 ? 56.073  64.247 45.864  1.00 0.46 ? 329 THR B CA  1 
ATOM 5702 C C   . THR B 1 329 ? 55.711  62.801 45.524  1.00 0.46 ? 329 THR B C   1 
ATOM 5703 O O   . THR B 1 329 ? 54.719  62.267 46.018  1.00 0.46 ? 329 THR B O   1 
ATOM 5704 C CB  . THR B 1 329 ? 56.794  64.274 47.215  1.00 0.46 ? 329 THR B CB  1 
ATOM 5705 O OG1 . THR B 1 329 ? 55.909  64.241 48.328  1.00 0.46 ? 329 THR B OG1 1 
ATOM 5706 C CG2 . THR B 1 329 ? 57.563  65.593 47.373  1.00 0.46 ? 329 THR B CG2 1 
ATOM 5707 N N   . TRP B 1 330 ? 56.529  62.108 44.696  1.00 0.40 ? 330 TRP B N   1 
ATOM 5708 C CA  . TRP B 1 330 ? 56.314  60.692 44.422  1.00 0.40 ? 330 TRP B CA  1 
ATOM 5709 C C   . TRP B 1 330 ? 57.636  59.943 44.295  1.00 0.40 ? 330 TRP B C   1 
ATOM 5710 O O   . TRP B 1 330 ? 58.701  60.548 44.246  1.00 0.40 ? 330 TRP B O   1 
ATOM 5711 C CB  . TRP B 1 330 ? 55.399  60.430 43.191  1.00 0.40 ? 330 TRP B CB  1 
ATOM 5712 C CG  . TRP B 1 330 ? 54.854  59.005 43.098  1.00 0.40 ? 330 TRP B CG  1 
ATOM 5713 C CD1 . TRP B 1 330 ? 54.034  58.386 43.998  1.00 0.40 ? 330 TRP B CD1 1 
ATOM 5714 C CD2 . TRP B 1 330 ? 55.270  57.983 42.168  1.00 0.40 ? 330 TRP B CD2 1 
ATOM 5715 N NE1 . TRP B 1 330 ? 53.893  57.052 43.680  1.00 0.40 ? 330 TRP B NE1 1 
ATOM 5716 C CE2 . TRP B 1 330 ? 54.662  56.779 42.577  1.00 0.40 ? 330 TRP B CE2 1 
ATOM 5717 C CE3 . TRP B 1 330 ? 56.138  58.006 41.082  1.00 0.40 ? 330 TRP B CE3 1 
ATOM 5718 C CZ2 . TRP B 1 330 ? 54.924  55.584 41.921  1.00 0.40 ? 330 TRP B CZ2 1 
ATOM 5719 C CZ3 . TRP B 1 330 ? 56.403  56.798 40.420  1.00 0.40 ? 330 TRP B CZ3 1 
ATOM 5720 C CH2 . TRP B 1 330 ? 55.812  55.599 40.837  1.00 0.40 ? 330 TRP B CH2 1 
ATOM 5721 N N   . LEU B 1 331 ? 57.559  58.593 44.310  1.00 0.49 ? 331 LEU B N   1 
ATOM 5722 C CA  . LEU B 1 331 ? 58.622  57.601 44.289  1.00 0.49 ? 331 LEU B CA  1 
ATOM 5723 C C   . LEU B 1 331 ? 59.681  57.728 43.203  1.00 0.49 ? 331 LEU B C   1 
ATOM 5724 O O   . LEU B 1 331 ? 59.395  57.782 42.009  1.00 0.49 ? 331 LEU B O   1 
ATOM 5725 C CB  . LEU B 1 331 ? 57.974  56.196 44.143  1.00 0.49 ? 331 LEU B CB  1 
ATOM 5726 C CG  . LEU B 1 331 ? 58.917  54.970 44.120  1.00 0.49 ? 331 LEU B CG  1 
ATOM 5727 C CD1 . LEU B 1 331 ? 59.623  54.732 45.464  1.00 0.49 ? 331 LEU B CD1 1 
ATOM 5728 C CD2 . LEU B 1 331 ? 58.144  53.715 43.679  1.00 0.49 ? 331 LEU B CD2 1 
ATOM 5729 N N   . THR B 1 332 ? 60.954  57.660 43.637  1.00 0.53 ? 332 THR B N   1 
ATOM 5730 C CA  . THR B 1 332 ? 62.141  57.615 42.800  1.00 0.53 ? 332 THR B CA  1 
ATOM 5731 C C   . THR B 1 332 ? 62.657  56.192 42.808  1.00 0.53 ? 332 THR B C   1 
ATOM 5732 O O   . THR B 1 332 ? 63.015  55.677 43.867  1.00 0.53 ? 332 THR B O   1 
ATOM 5733 C CB  . THR B 1 332 ? 63.284  58.457 43.361  1.00 0.53 ? 332 THR B CB  1 
ATOM 5734 O OG1 . THR B 1 332 ? 62.868  59.767 43.692  1.00 0.53 ? 332 THR B OG1 1 
ATOM 5735 C CG2 . THR B 1 332 ? 64.447  58.552 42.362  1.00 0.53 ? 332 THR B CG2 1 
ATOM 5736 N N   . TYR B 1 333 ? 62.725  55.500 41.647  1.00 0.40 ? 333 TYR B N   1 
ATOM 5737 C CA  . TYR B 1 333 ? 63.168  54.112 41.597  1.00 0.40 ? 333 TYR B CA  1 
ATOM 5738 C C   . TYR B 1 333 ? 63.664  53.754 40.193  1.00 0.40 ? 333 TYR B C   1 
ATOM 5739 O O   . TYR B 1 333 ? 63.317  54.436 39.230  1.00 0.40 ? 333 TYR B O   1 
ATOM 5740 C CB  . TYR B 1 333 ? 62.057  53.122 42.071  1.00 0.40 ? 333 TYR B CB  1 
ATOM 5741 C CG  . TYR B 1 333 ? 61.030  52.787 41.010  1.00 0.40 ? 333 TYR B CG  1 
ATOM 5742 C CD1 . TYR B 1 333 ? 60.064  53.718 40.597  1.00 0.40 ? 333 TYR B CD1 1 
ATOM 5743 C CD2 . TYR B 1 333 ? 61.084  51.539 40.365  1.00 0.40 ? 333 TYR B CD2 1 
ATOM 5744 C CE1 . TYR B 1 333 ? 59.134  53.384 39.601  1.00 0.40 ? 333 TYR B CE1 1 
ATOM 5745 C CE2 . TYR B 1 333 ? 60.166  51.209 39.365  1.00 0.40 ? 333 TYR B CE2 1 
ATOM 5746 C CZ  . TYR B 1 333 ? 59.165  52.115 39.015  1.00 0.40 ? 333 TYR B CZ  1 
ATOM 5747 O OH  . TYR B 1 333 ? 58.165  51.716 38.115  1.00 0.40 ? 333 TYR B OH  1 
ATOM 5748 N N   . THR B 1 334 ? 64.485  52.688 40.024  1.00 0.44 ? 334 THR B N   1 
ATOM 5749 C CA  . THR B 1 334 ? 64.981  52.305 38.702  1.00 0.44 ? 334 THR B CA  1 
ATOM 5750 C C   . THR B 1 334 ? 65.214  50.801 38.573  1.00 0.44 ? 334 THR B C   1 
ATOM 5751 O O   . THR B 1 334 ? 65.938  50.227 39.375  1.00 0.44 ? 334 THR B O   1 
ATOM 5752 C CB  . THR B 1 334 ? 66.364  52.895 38.417  1.00 0.44 ? 334 THR B CB  1 
ATOM 5753 O OG1 . THR B 1 334 ? 66.453  54.295 38.587  1.00 0.44 ? 334 THR B OG1 1 
ATOM 5754 C CG2 . THR B 1 334 ? 66.773  52.723 36.954  1.00 0.44 ? 334 THR B CG2 1 
ATOM 5755 N N   . GLY B 1 335 ? 64.708  50.141 37.500  1.00 0.48 ? 335 GLY B N   1 
ATOM 5756 C CA  . GLY B 1 335 ? 65.124  48.779 37.123  1.00 0.48 ? 335 GLY B CA  1 
ATOM 5757 C C   . GLY B 1 335 ? 64.339  47.603 37.676  1.00 0.48 ? 335 GLY B C   1 
ATOM 5758 O O   . GLY B 1 335 ? 63.616  47.694 38.664  1.00 0.48 ? 335 GLY B O   1 
ATOM 5759 N N   . ALA B 1 336 ? 64.453  46.449 36.977  1.00 0.50 ? 336 ALA B N   1 
ATOM 5760 C CA  . ALA B 1 336 ? 63.913  45.158 37.371  1.00 0.50 ? 336 ALA B CA  1 
ATOM 5761 C C   . ALA B 1 336 ? 64.804  44.438 38.387  1.00 0.50 ? 336 ALA B C   1 
ATOM 5762 O O   . ALA B 1 336 ? 65.906  44.883 38.700  1.00 0.50 ? 336 ALA B O   1 
ATOM 5763 C CB  . ALA B 1 336 ? 63.756  44.257 36.121  1.00 0.50 ? 336 ALA B CB  1 
ATOM 5764 N N   . ILE B 1 337 ? 64.333  43.300 38.945  1.00 0.45 ? 337 ILE B N   1 
ATOM 5765 C CA  . ILE B 1 337 ? 65.122  42.454 39.835  1.00 0.45 ? 337 ILE B CA  1 
ATOM 5766 C C   . ILE B 1 337 ? 66.422  41.886 39.259  1.00 0.45 ? 337 ILE B C   1 
ATOM 5767 O O   . ILE B 1 337 ? 66.577  41.636 38.064  1.00 0.45 ? 337 ILE B O   1 
ATOM 5768 C CB  . ILE B 1 337 ? 64.349  41.293 40.463  1.00 0.45 ? 337 ILE B CB  1 
ATOM 5769 C CG1 . ILE B 1 337 ? 63.977  40.176 39.458  1.00 0.45 ? 337 ILE B CG1 1 
ATOM 5770 C CG2 . ILE B 1 337 ? 63.108  41.842 41.194  1.00 0.45 ? 337 ILE B CG2 1 
ATOM 5771 C CD1 . ILE B 1 337 ? 63.642  38.847 40.148  1.00 0.45 ? 337 ILE B CD1 1 
ATOM 5772 N N   . LYS B 1 338 ? 67.410  41.650 40.141  1.00 0.43 ? 338 LYS B N   1 
ATOM 5773 C CA  . LYS B 1 338 ? 68.617  40.900 39.844  1.00 0.43 ? 338 LYS B CA  1 
ATOM 5774 C C   . LYS B 1 338 ? 68.357  39.407 39.633  1.00 0.43 ? 338 LYS B C   1 
ATOM 5775 O O   . LYS B 1 338 ? 67.448  38.839 40.234  1.00 0.43 ? 338 LYS B O   1 
ATOM 5776 C CB  . LYS B 1 338 ? 69.645  41.071 40.988  1.00 0.43 ? 338 LYS B CB  1 
ATOM 5777 C CG  . LYS B 1 338 ? 70.074  42.533 41.193  1.00 0.43 ? 338 LYS B CG  1 
ATOM 5778 C CD  . LYS B 1 338 ? 71.070  42.731 42.350  1.00 0.43 ? 338 LYS B CD  1 
ATOM 5779 C CE  . LYS B 1 338 ? 70.446  42.478 43.727  1.00 0.43 ? 338 LYS B CE  1 
ATOM 5780 N NZ  . LYS B 1 338 ? 71.395  42.794 44.816  1.00 0.43 ? 338 LYS B NZ  1 
ATOM 5781 N N   . LEU B 1 339 ? 69.172  38.730 38.798  1.00 0.42 ? 339 LEU B N   1 
ATOM 5782 C CA  . LEU B 1 339 ? 69.018  37.316 38.497  1.00 0.42 ? 339 LEU B CA  1 
ATOM 5783 C C   . LEU B 1 339 ? 70.383  36.642 38.526  1.00 0.42 ? 339 LEU B C   1 
ATOM 5784 O O   . LEU B 1 339 ? 71.404  37.321 38.449  1.00 0.42 ? 339 LEU B O   1 
ATOM 5785 C CB  . LEU B 1 339 ? 68.394  37.110 37.089  1.00 0.42 ? 339 LEU B CB  1 
ATOM 5786 C CG  . LEU B 1 339 ? 66.903  37.490 36.964  1.00 0.42 ? 339 LEU B CG  1 
ATOM 5787 C CD1 . LEU B 1 339 ? 66.443  37.391 35.501  1.00 0.42 ? 339 LEU B CD1 1 
ATOM 5788 C CD2 . LEU B 1 339 ? 66.008  36.614 37.856  1.00 0.42 ? 339 LEU B CD2 1 
ATOM 5789 N N   . ASP B 1 340 ? 70.408  35.294 38.642  1.00 0.42 ? 340 ASP B N   1 
ATOM 5790 C CA  . ASP B 1 340 ? 71.598  34.465 38.624  1.00 0.42 ? 340 ASP B CA  1 
ATOM 5791 C C   . ASP B 1 340 ? 71.475  33.539 37.415  1.00 0.42 ? 340 ASP B C   1 
ATOM 5792 O O   . ASP B 1 340 ? 70.448  32.885 37.229  1.00 0.42 ? 340 ASP B O   1 
ATOM 5793 C CB  . ASP B 1 340 ? 71.675  33.656 39.962  1.00 0.42 ? 340 ASP B CB  1 
ATOM 5794 C CG  . ASP B 1 340 ? 72.866  32.709 40.114  1.00 0.42 ? 340 ASP B CG  1 
ATOM 5795 O OD1 . ASP B 1 340 ? 73.653  32.537 39.147  1.00 0.42 ? 340 ASP B OD1 1 
ATOM 5796 O OD2 . ASP B 1 340 ? 72.973  32.104 41.209  1.00 0.42 ? 340 ASP B OD2 1 
ATOM 5797 N N   . ASP B 1 341 ? 72.529  33.450 36.573  1.00 0.46 ? 341 ASP B N   1 
ATOM 5798 C CA  . ASP B 1 341 ? 72.652  32.566 35.431  1.00 0.46 ? 341 ASP B CA  1 
ATOM 5799 C C   . ASP B 1 341 ? 72.569  31.079 35.788  1.00 0.46 ? 341 ASP B C   1 
ATOM 5800 O O   . ASP B 1 341 ? 72.267  30.235 34.944  1.00 0.46 ? 341 ASP B O   1 
ATOM 5801 C CB  . ASP B 1 341 ? 74.003  32.783 34.685  1.00 0.46 ? 341 ASP B CB  1 
ATOM 5802 C CG  . ASP B 1 341 ? 74.303  34.240 34.360  1.00 0.46 ? 341 ASP B CG  1 
ATOM 5803 O OD1 . ASP B 1 341 ? 74.416  35.041 35.323  1.00 0.46 ? 341 ASP B OD1 1 
ATOM 5804 O OD2 . ASP B 1 341 ? 74.519  34.529 33.157  1.00 0.46 ? 341 ASP B OD2 1 
ATOM 5805 N N   . LYS B 1 342 ? 72.869  30.712 37.054  1.00 0.47 ? 342 LYS B N   1 
ATOM 5806 C CA  . LYS B 1 342 ? 72.853  29.334 37.508  1.00 0.47 ? 342 LYS B CA  1 
ATOM 5807 C C   . LYS B 1 342 ? 71.479  28.884 37.992  1.00 0.47 ? 342 LYS B C   1 
ATOM 5808 O O   . LYS B 1 342 ? 71.267  27.691 38.218  1.00 0.47 ? 342 LYS B O   1 
ATOM 5809 C CB  . LYS B 1 342 ? 73.885  29.115 38.648  1.00 0.47 ? 342 LYS B CB  1 
ATOM 5810 C CG  . LYS B 1 342 ? 75.331  28.846 38.188  1.00 0.47 ? 342 LYS B CG  1 
ATOM 5811 C CD  . LYS B 1 342 ? 76.013  30.014 37.458  1.00 0.47 ? 342 LYS B CD  1 
ATOM 5812 C CE  . LYS B 1 342 ? 77.496  29.746 37.204  1.00 0.47 ? 342 LYS B CE  1 
ATOM 5813 N NZ  . LYS B 1 342 ? 78.110  30.894 36.504  1.00 0.47 ? 342 LYS B NZ  1 
ATOM 5814 N N   . ASP B 1 343 ? 70.496  29.800 38.149  1.00 0.53 ? 343 ASP B N   1 
ATOM 5815 C CA  . ASP B 1 343 ? 69.126  29.456 38.493  1.00 0.53 ? 343 ASP B CA  1 
ATOM 5816 C C   . ASP B 1 343 ? 68.465  28.611 37.377  1.00 0.53 ? 343 ASP B C   1 
ATOM 5817 O O   . ASP B 1 343 ? 68.525  29.017 36.213  1.00 0.53 ? 343 ASP B O   1 
ATOM 5818 C CB  . ASP B 1 343 ? 68.364  30.786 38.803  1.00 0.53 ? 343 ASP B CB  1 
ATOM 5819 C CG  . ASP B 1 343 ? 66.904  30.674 39.222  1.00 0.53 ? 343 ASP B CG  1 
ATOM 5820 O OD1 . ASP B 1 343 ? 66.293  29.585 39.071  1.00 0.53 ? 343 ASP B OD1 1 
ATOM 5821 O OD2 . ASP B 1 343 ? 66.345  31.715 39.642  1.00 0.53 ? 343 ASP B OD2 1 
ATOM 5822 N N   . PRO B 1 344 ? 67.806  27.466 37.606  1.00 0.54 ? 344 PRO B N   1 
ATOM 5823 C CA  . PRO B 1 344 ? 67.089  26.721 36.573  1.00 0.54 ? 344 PRO B CA  1 
ATOM 5824 C C   . PRO B 1 344 ? 65.977  27.514 35.896  1.00 0.54 ? 344 PRO B C   1 
ATOM 5825 O O   . PRO B 1 344 ? 65.624  27.197 34.760  1.00 0.54 ? 344 PRO B O   1 
ATOM 5826 C CB  . PRO B 1 344 ? 66.590  25.454 37.294  1.00 0.54 ? 344 PRO B CB  1 
ATOM 5827 C CG  . PRO B 1 344 ? 66.548  25.847 38.771  1.00 0.54 ? 344 PRO B CG  1 
ATOM 5828 C CD  . PRO B 1 344 ? 67.727  26.806 38.907  1.00 0.54 ? 344 PRO B CD  1 
ATOM 5829 N N   . ASN B 1 345 ? 65.418  28.550 36.559  1.00 0.60 ? 345 ASN B N   1 
ATOM 5830 C CA  . ASN B 1 345 ? 64.392  29.413 36.003  1.00 0.60 ? 345 ASN B CA  1 
ATOM 5831 C C   . ASN B 1 345 ? 64.968  30.424 35.009  1.00 0.60 ? 345 ASN B C   1 
ATOM 5832 O O   . ASN B 1 345 ? 64.257  30.965 34.164  1.00 0.60 ? 345 ASN B O   1 
ATOM 5833 C CB  . ASN B 1 345 ? 63.659  30.202 37.116  1.00 0.60 ? 345 ASN B CB  1 
ATOM 5834 C CG  . ASN B 1 345 ? 62.970  29.257 38.093  1.00 0.60 ? 345 ASN B CG  1 
ATOM 5835 O OD1 . ASN B 1 345 ? 61.832  28.834 37.881  1.00 0.60 ? 345 ASN B OD1 1 
ATOM 5836 N ND2 . ASN B 1 345 ? 63.653  28.922 39.209  1.00 0.60 ? 345 ASN B ND2 1 
ATOM 5837 N N   . PHE B 1 346 ? 66.299  30.679 35.050  1.00 0.51 ? 346 PHE B N   1 
ATOM 5838 C CA  . PHE B 1 346 ? 66.993  31.628 34.188  1.00 0.51 ? 346 PHE B CA  1 
ATOM 5839 C C   . PHE B 1 346 ? 66.885  31.268 32.715  1.00 0.51 ? 346 PHE B C   1 
ATOM 5840 O O   . PHE B 1 346 ? 66.745  32.139 31.866  1.00 0.51 ? 346 PHE B O   1 
ATOM 5841 C CB  . PHE B 1 346 ? 68.475  31.792 34.611  1.00 0.51 ? 346 PHE B CB  1 
ATOM 5842 C CG  . PHE B 1 346 ? 69.182  32.891 33.862  1.00 0.51 ? 346 PHE B CG  1 
ATOM 5843 C CD1 . PHE B 1 346 ? 69.019  34.233 34.235  1.00 0.51 ? 346 PHE B CD1 1 
ATOM 5844 C CD2 . PHE B 1 346 ? 70.046  32.584 32.797  1.00 0.51 ? 346 PHE B CD2 1 
ATOM 5845 C CE1 . PHE B 1 346 ? 69.725  35.249 33.580  1.00 0.51 ? 346 PHE B CE1 1 
ATOM 5846 C CE2 . PHE B 1 346 ? 70.757  33.595 32.142  1.00 0.51 ? 346 PHE B CE2 1 
ATOM 5847 C CZ  . PHE B 1 346 ? 70.602  34.928 32.538  1.00 0.51 ? 346 PHE B CZ  1 
ATOM 5848 N N   . LYS B 1 347 ? 66.876  29.958 32.399  1.00 0.51 ? 347 LYS B N   1 
ATOM 5849 C CA  . LYS B 1 347 ? 66.683  29.414 31.066  1.00 0.51 ? 347 LYS B CA  1 
ATOM 5850 C C   . LYS B 1 347 ? 65.409  29.916 30.385  1.00 0.51 ? 347 LYS B C   1 
ATOM 5851 O O   . LYS B 1 347 ? 65.404  30.185 29.184  1.00 0.51 ? 347 LYS B O   1 
ATOM 5852 C CB  . LYS B 1 347 ? 66.710  27.864 31.187  1.00 0.51 ? 347 LYS B CB  1 
ATOM 5853 C CG  . LYS B 1 347 ? 66.501  27.048 29.892  1.00 0.51 ? 347 LYS B CG  1 
ATOM 5854 C CD  . LYS B 1 347 ? 65.033  26.695 29.558  1.00 0.51 ? 347 LYS B CD  1 
ATOM 5855 C CE  . LYS B 1 347 ? 64.346  25.789 30.589  1.00 0.51 ? 347 LYS B CE  1 
ATOM 5856 N NZ  . LYS B 1 347 ? 62.904  25.693 30.300  1.00 0.51 ? 347 LYS B NZ  1 
ATOM 5857 N N   . ASP B 1 348 ? 64.300  30.079 31.138  1.00 0.55 ? 348 ASP B N   1 
ATOM 5858 C CA  . ASP B 1 348 ? 63.104  30.723 30.634  1.00 0.55 ? 348 ASP B CA  1 
ATOM 5859 C C   . ASP B 1 348 ? 63.227  32.249 30.702  1.00 0.55 ? 348 ASP B C   1 
ATOM 5860 O O   . ASP B 1 348 ? 62.995  32.957 29.723  1.00 0.55 ? 348 ASP B O   1 
ATOM 5861 C CB  . ASP B 1 348 ? 61.863  30.295 31.463  1.00 0.55 ? 348 ASP B CB  1 
ATOM 5862 C CG  . ASP B 1 348 ? 61.453  28.847 31.263  1.00 0.55 ? 348 ASP B CG  1 
ATOM 5863 O OD1 . ASP B 1 348 ? 62.124  28.122 30.484  1.00 0.55 ? 348 ASP B OD1 1 
ATOM 5864 O OD2 . ASP B 1 348 ? 60.441  28.427 31.880  1.00 0.55 ? 348 ASP B OD2 1 
ATOM 5865 N N   . GLN B 1 349 ? 63.644  32.805 31.862  1.00 0.64 ? 349 GLN B N   1 
ATOM 5866 C CA  . GLN B 1 349 ? 63.654  34.242 32.115  1.00 0.64 ? 349 GLN B CA  1 
ATOM 5867 C C   . GLN B 1 349 ? 64.531  35.056 31.186  1.00 0.64 ? 349 GLN B C   1 
ATOM 5868 O O   . GLN B 1 349 ? 64.160  36.162 30.800  1.00 0.64 ? 349 GLN B O   1 
ATOM 5869 C CB  . GLN B 1 349 ? 64.000  34.597 33.584  1.00 0.64 ? 349 GLN B CB  1 
ATOM 5870 C CG  . GLN B 1 349 ? 62.984  34.060 34.626  1.00 0.64 ? 349 GLN B CG  1 
ATOM 5871 C CD  . GLN B 1 349 ? 61.654  34.821 34.628  1.00 0.64 ? 349 GLN B CD  1 
ATOM 5872 O OE1 . GLN B 1 349 ? 61.045  35.111 33.600  1.00 0.64 ? 349 GLN B OE1 1 
ATOM 5873 N NE2 . GLN B 1 349 ? 61.173  35.179 35.842  1.00 0.64 ? 349 GLN B NE2 1 
ATOM 5874 N N   . VAL B 1 350 ? 65.690  34.521 30.767  1.00 0.57 ? 350 VAL B N   1 
ATOM 5875 C CA  . VAL B 1 350 ? 66.612  35.169 29.853  1.00 0.57 ? 350 VAL B CA  1 
ATOM 5876 C C   . VAL B 1 350 ? 66.004  35.491 28.482  1.00 0.57 ? 350 VAL B C   1 
ATOM 5877 O O   . VAL B 1 350 ? 66.402  36.468 27.861  1.00 0.57 ? 350 VAL B O   1 
ATOM 5878 C CB  . VAL B 1 350 ? 67.943  34.412 29.804  1.00 0.57 ? 350 VAL B CB  1 
ATOM 5879 C CG1 . VAL B 1 350 ? 67.867  33.131 28.948  1.00 0.57 ? 350 VAL B CG1 1 
ATOM 5880 C CG2 . VAL B 1 350 ? 69.086  35.343 29.359  1.00 0.57 ? 350 VAL B CG2 1 
ATOM 5881 N N   . ILE B 1 351 ? 64.963  34.739 28.026  1.00 0.58 ? 351 ILE B N   1 
ATOM 5882 C CA  . ILE B 1 351 ? 64.215  35.067 26.814  1.00 0.58 ? 351 ILE B CA  1 
ATOM 5883 C C   . ILE B 1 351 ? 62.829  35.644 27.105  1.00 0.58 ? 351 ILE B C   1 
ATOM 5884 O O   . ILE B 1 351 ? 62.275  36.409 26.309  1.00 0.58 ? 351 ILE B O   1 
ATOM 5885 C CB  . ILE B 1 351 ? 64.039  33.869 25.877  1.00 0.58 ? 351 ILE B CB  1 
ATOM 5886 C CG1 . ILE B 1 351 ? 63.436  32.619 26.568  1.00 0.58 ? 351 ILE B CG1 1 
ATOM 5887 C CG2 . ILE B 1 351 ? 65.418  33.583 25.251  1.00 0.58 ? 351 ILE B CG2 1 
ATOM 5888 C CD1 . ILE B 1 351 ? 63.089  31.484 25.599  1.00 0.58 ? 351 ILE B CD1 1 
ATOM 5889 N N   . LEU B 1 352 ? 62.214  35.324 28.266  1.00 0.63 ? 352 LEU B N   1 
ATOM 5890 C CA  . LEU B 1 352 ? 60.952  35.895 28.721  1.00 0.63 ? 352 LEU B CA  1 
ATOM 5891 C C   . LEU B 1 352 ? 61.062  37.388 29.014  1.00 0.63 ? 352 LEU B C   1 
ATOM 5892 O O   . LEU B 1 352 ? 60.141  38.154 28.751  1.00 0.63 ? 352 LEU B O   1 
ATOM 5893 C CB  . LEU B 1 352 ? 60.323  35.099 29.900  1.00 0.63 ? 352 LEU B CB  1 
ATOM 5894 C CG  . LEU B 1 352 ? 59.288  34.016 29.493  1.00 0.63 ? 352 LEU B CG  1 
ATOM 5895 C CD1 . LEU B 1 352 ? 59.860  32.916 28.582  1.00 0.63 ? 352 LEU B CD1 1 
ATOM 5896 C CD2 . LEU B 1 352 ? 58.672  33.377 30.749  1.00 0.63 ? 352 LEU B CD2 1 
ATOM 5897 N N   . LEU B 1 353 ? 62.220  37.882 29.490  1.00 0.61 ? 353 LEU B N   1 
ATOM 5898 C CA  . LEU B 1 353 ? 62.451  39.311 29.641  1.00 0.61 ? 353 LEU B CA  1 
ATOM 5899 C C   . LEU B 1 353 ? 62.275  40.120 28.355  1.00 0.61 ? 353 LEU B C   1 
ATOM 5900 O O   . LEU B 1 353 ? 61.580  41.138 28.325  1.00 0.61 ? 353 LEU B O   1 
ATOM 5901 C CB  . LEU B 1 353 ? 63.900  39.529 30.131  1.00 0.61 ? 353 LEU B CB  1 
ATOM 5902 C CG  . LEU B 1 353 ? 64.118  39.249 31.630  1.00 0.61 ? 353 LEU B CG  1 
ATOM 5903 C CD1 . LEU B 1 353 ? 65.598  38.958 31.916  1.00 0.61 ? 353 LEU B CD1 1 
ATOM 5904 C CD2 . LEU B 1 353 ? 63.638  40.420 32.498  1.00 0.61 ? 353 LEU B CD2 1 
ATOM 5905 N N   . ASN B 1 354 ? 62.860  39.658 27.237  1.00 0.60 ? 354 ASN B N   1 
ATOM 5906 C CA  . ASN B 1 354 ? 62.776  40.308 25.941  1.00 0.60 ? 354 ASN B CA  1 
ATOM 5907 C C   . ASN B 1 354 ? 61.410  40.279 25.315  1.00 0.60 ? 354 ASN B C   1 
ATOM 5908 O O   . ASN B 1 354 ? 61.033  41.189 24.586  1.00 0.60 ? 354 ASN B O   1 
ATOM 5909 C CB  . ASN B 1 354 ? 63.799  39.699 24.973  1.00 0.60 ? 354 ASN B CB  1 
ATOM 5910 C CG  . ASN B 1 354 ? 65.164  39.919 25.626  1.00 0.60 ? 354 ASN B CG  1 
ATOM 5911 O OD1 . ASN B 1 354 ? 65.587  39.161 26.495  1.00 0.60 ? 354 ASN B OD1 1 
ATOM 5912 N ND2 . ASN B 1 354 ? 65.800  41.083 25.363  1.00 0.60 ? 354 ASN B ND2 1 
ATOM 5913 N N   . LYS B 1 355 ? 60.623  39.238 25.612  1.00 0.59 ? 355 LYS B N   1 
ATOM 5914 C CA  . LYS B 1 355 ? 59.246  39.161 25.187  1.00 0.59 ? 355 LYS B CA  1 
ATOM 5915 C C   . LYS B 1 355 ? 58.300  40.120 25.906  1.00 0.59 ? 355 LYS B C   1 
ATOM 5916 O O   . LYS B 1 355 ? 57.247  40.452 25.367  1.00 0.59 ? 355 LYS B O   1 
ATOM 5917 C CB  . LYS B 1 355 ? 58.721  37.720 25.392  1.00 0.59 ? 355 LYS B CB  1 
ATOM 5918 C CG  . LYS B 1 355 ? 59.307  36.713 24.390  1.00 0.59 ? 355 LYS B CG  1 
ATOM 5919 C CD  . LYS B 1 355 ? 58.862  35.271 24.689  1.00 0.59 ? 355 LYS B CD  1 
ATOM 5920 C CE  . LYS B 1 355 ? 59.293  34.243 23.639  1.00 0.59 ? 355 LYS B CE  1 
ATOM 5921 N NZ  . LYS B 1 355 ? 58.391  34.312 22.465  1.00 0.59 ? 355 LYS B NZ  1 
ATOM 5922 N N   . HIS B 1 356 ? 58.630  40.588 27.131  1.00 0.65 ? 356 HIS B N   1 
ATOM 5923 C CA  . HIS B 1 356 ? 57.640  41.245 27.970  1.00 0.65 ? 356 HIS B CA  1 
ATOM 5924 C C   . HIS B 1 356 ? 58.016  42.620 28.522  1.00 0.65 ? 356 HIS B C   1 
ATOM 5925 O O   . HIS B 1 356 ? 57.120  43.362 28.933  1.00 0.65 ? 356 HIS B O   1 
ATOM 5926 C CB  . HIS B 1 356 ? 57.238  40.298 29.117  1.00 0.65 ? 356 HIS B CB  1 
ATOM 5927 C CG  . HIS B 1 356 ? 56.539  39.068 28.609  1.00 0.65 ? 356 HIS B CG  1 
ATOM 5928 N ND1 . HIS B 1 356 ? 57.126  37.832 28.768  1.00 0.65 ? 356 HIS B ND1 1 
ATOM 5929 C CD2 . HIS B 1 356 ? 55.355  38.938 27.950  1.00 0.65 ? 356 HIS B CD2 1 
ATOM 5930 C CE1 . HIS B 1 356 ? 56.304  36.976 28.201  1.00 0.65 ? 356 HIS B CE1 1 
ATOM 5931 N NE2 . HIS B 1 356 ? 55.214  37.592 27.689  1.00 0.65 ? 356 HIS B NE2 1 
ATOM 5932 N N   . ILE B 1 357 ? 59.305  43.030 28.541  1.00 0.62 ? 357 ILE B N   1 
ATOM 5933 C CA  . ILE B 1 357 ? 59.736  44.405 28.829  1.00 0.62 ? 357 ILE B CA  1 
ATOM 5934 C C   . ILE B 1 357 ? 59.400  45.373 27.686  1.00 0.62 ? 357 ILE B C   1 
ATOM 5935 O O   . ILE B 1 357 ? 59.707  45.100 26.530  1.00 0.62 ? 357 ILE B O   1 
ATOM 5936 C CB  . ILE B 1 357 ? 61.232  44.463 29.173  1.00 0.62 ? 357 ILE B CB  1 
ATOM 5937 C CG1 . ILE B 1 357 ? 61.474  43.807 30.554  1.00 0.62 ? 357 ILE B CG1 1 
ATOM 5938 C CG2 . ILE B 1 357 ? 61.792  45.909 29.155  1.00 0.62 ? 357 ILE B CG2 1 
ATOM 5939 C CD1 . ILE B 1 357 ? 62.950  43.581 30.901  1.00 0.62 ? 357 ILE B CD1 1 
ATOM 5940 N N   . ASP B 1 358 ? 58.718  46.514 27.990  1.00 0.61 ? 358 ASP B N   1 
ATOM 5941 C CA  . ASP B 1 358 ? 58.332  47.587 27.061  1.00 0.61 ? 358 ASP B CA  1 
ATOM 5942 C C   . ASP B 1 358 ? 57.402  47.085 25.940  1.00 0.61 ? 358 ASP B C   1 
ATOM 5943 O O   . ASP B 1 358 ? 57.197  47.695 24.892  1.00 0.61 ? 358 ASP B O   1 
ATOM 5944 C CB  . ASP B 1 358 ? 59.571  48.390 26.543  1.00 0.61 ? 358 ASP B CB  1 
ATOM 5945 C CG  . ASP B 1 358 ? 59.257  49.752 25.931  1.00 0.61 ? 358 ASP B CG  1 
ATOM 5946 O OD1 . ASP B 1 358 ? 58.185  50.343 26.210  1.00 0.61 ? 358 ASP B OD1 1 
ATOM 5947 O OD2 . ASP B 1 358 ? 60.130  50.257 25.168  1.00 0.61 ? 358 ASP B OD2 1 
ATOM 5948 N N   . ALA B 1 359 ? 56.752  45.923 26.155  1.00 0.69 ? 359 ALA B N   1 
ATOM 5949 C CA  . ALA B 1 359 ? 56.221  45.134 25.063  1.00 0.69 ? 359 ALA B CA  1 
ATOM 5950 C C   . ALA B 1 359 ? 54.957  45.668 24.399  1.00 0.69 ? 359 ALA B C   1 
ATOM 5951 O O   . ALA B 1 359 ? 54.627  45.291 23.283  1.00 0.69 ? 359 ALA B O   1 
ATOM 5952 C CB  . ALA B 1 359 ? 56.029  43.690 25.558  1.00 0.69 ? 359 ALA B CB  1 
ATOM 5953 N N   . TYR B 1 360 ? 54.258  46.619 25.039  1.00 0.54 ? 360 TYR B N   1 
ATOM 5954 C CA  . TYR B 1 360 ? 53.116  47.333 24.488  1.00 0.54 ? 360 TYR B CA  1 
ATOM 5955 C C   . TYR B 1 360 ? 53.492  48.260 23.317  1.00 0.54 ? 360 TYR B C   1 
ATOM 5956 O O   . TYR B 1 360 ? 52.660  48.618 22.484  1.00 0.54 ? 360 TYR B O   1 
ATOM 5957 C CB  . TYR B 1 360 ? 52.482  48.154 25.647  1.00 0.54 ? 360 TYR B CB  1 
ATOM 5958 C CG  . TYR B 1 360 ? 51.304  48.976 25.213  1.00 0.54 ? 360 TYR B CG  1 
ATOM 5959 C CD1 . TYR B 1 360 ? 50.127  48.370 24.746  1.00 0.54 ? 360 TYR B CD1 1 
ATOM 5960 C CD2 . TYR B 1 360 ? 51.406  50.374 25.204  1.00 0.54 ? 360 TYR B CD2 1 
ATOM 5961 C CE1 . TYR B 1 360 ? 49.063  49.156 24.278  1.00 0.54 ? 360 TYR B CE1 1 
ATOM 5962 C CE2 . TYR B 1 360 ? 50.343  51.156 24.749  1.00 0.54 ? 360 TYR B CE2 1 
ATOM 5963 C CZ  . TYR B 1 360 ? 49.181  50.545 24.281  1.00 0.54 ? 360 TYR B CZ  1 
ATOM 5964 O OH  . TYR B 1 360 ? 48.158  51.386 23.828  1.00 0.54 ? 360 TYR B OH  1 
ATOM 5965 N N   . LYS B 1 361 ? 54.769  48.677 23.220  1.00 0.55 ? 361 LYS B N   1 
ATOM 5966 C CA  . LYS B 1 361 ? 55.261  49.563 22.180  1.00 0.55 ? 361 LYS B CA  1 
ATOM 5967 C C   . LYS B 1 361 ? 55.140  49.030 20.757  1.00 0.55 ? 361 LYS B C   1 
ATOM 5968 O O   . LYS B 1 361 ? 55.066  49.808 19.814  1.00 0.55 ? 361 LYS B O   1 
ATOM 5969 C CB  . LYS B 1 361 ? 56.731  49.926 22.474  1.00 0.55 ? 361 LYS B CB  1 
ATOM 5970 C CG  . LYS B 1 361 ? 57.371  50.915 21.482  1.00 0.55 ? 361 LYS B CG  1 
ATOM 5971 C CD  . LYS B 1 361 ? 58.786  51.311 21.918  1.00 0.55 ? 361 LYS B CD  1 
ATOM 5972 C CE  . LYS B 1 361 ? 58.779  52.322 23.065  1.00 0.55 ? 361 LYS B CE  1 
ATOM 5973 N NZ  . LYS B 1 361 ? 60.108  52.380 23.696  1.00 0.55 ? 361 LYS B NZ  1 
ATOM 5974 N N   . THR B 1 362 ? 55.082  47.702 20.562  1.00 0.52 ? 362 THR B N   1 
ATOM 5975 C CA  . THR B 1 362 ? 54.999  47.112 19.237  1.00 0.52 ? 362 THR B CA  1 
ATOM 5976 C C   . THR B 1 362 ? 53.573  46.808 18.794  1.00 0.52 ? 362 THR B C   1 
ATOM 5977 O O   . THR B 1 362 ? 53.343  46.154 17.779  1.00 0.52 ? 362 THR B O   1 
ATOM 5978 C CB  . THR B 1 362 ? 55.847  45.862 19.119  1.00 0.52 ? 362 THR B CB  1 
ATOM 5979 O OG1 . THR B 1 362 ? 55.582  44.909 20.126  1.00 0.52 ? 362 THR B OG1 1 
ATOM 5980 C CG2 . THR B 1 362 ? 57.336  46.188 19.299  1.00 0.52 ? 362 THR B CG2 1 
ATOM 5981 N N   . PHE B 1 363 ? 52.552  47.311 19.521  1.00 0.45 ? 363 PHE B N   1 
ATOM 5982 C CA  . PHE B 1 363 ? 51.161  47.296 19.087  1.00 0.45 ? 363 PHE B CA  1 
ATOM 5983 C C   . PHE B 1 363 ? 50.950  48.181 17.828  1.00 0.45 ? 363 PHE B C   1 
ATOM 5984 O O   . PHE B 1 363 ? 51.616  49.208 17.718  1.00 0.45 ? 363 PHE B O   1 
ATOM 5985 C CB  . PHE B 1 363 ? 50.247  47.731 20.286  1.00 0.45 ? 363 PHE B CB  1 
ATOM 5986 C CG  . PHE B 1 363 ? 48.800  47.321 20.182  1.00 0.45 ? 363 PHE B CG  1 
ATOM 5987 C CD1 . PHE B 1 363 ? 48.455  45.996 19.887  1.00 0.45 ? 363 PHE B CD1 1 
ATOM 5988 C CD2 . PHE B 1 363 ? 47.765  48.248 20.412  1.00 0.45 ? 363 PHE B CD2 1 
ATOM 5989 C CE1 . PHE B 1 363 ? 47.117  45.623 19.728  1.00 0.45 ? 363 PHE B CE1 1 
ATOM 5990 C CE2 . PHE B 1 363 ? 46.423  47.881 20.248  1.00 0.45 ? 363 PHE B CE2 1 
ATOM 5991 C CZ  . PHE B 1 363 ? 46.099  46.567 19.891  1.00 0.45 ? 363 PHE B CZ  1 
ATOM 5992 N N   . PRO B 1 364 ? 50.079  47.928 16.844  1.00 0.34 ? 364 PRO B N   1 
ATOM 5993 C CA  . PRO B 1 364 ? 49.962  48.759 15.635  1.00 0.34 ? 364 PRO B CA  1 
ATOM 5994 C C   . PRO B 1 364 ? 49.716  50.266 15.798  1.00 0.34 ? 364 PRO B C   1 
ATOM 5995 O O   . PRO B 1 364 ? 50.166  50.977 14.902  1.00 0.34 ? 364 PRO B O   1 
ATOM 5996 C CB  . PRO B 1 364 ? 48.843  48.089 14.814  1.00 0.34 ? 364 PRO B CB  1 
ATOM 5997 C CG  . PRO B 1 364 ? 48.797  46.644 15.320  1.00 0.34 ? 364 PRO B CG  1 
ATOM 5998 C CD  . PRO B 1 364 ? 49.204  46.762 16.786  1.00 0.34 ? 364 PRO B CD  1 
ATOM 5999 N N   . PRO B 1 365 ? 49.038  50.841 16.795  1.00 0.43 ? 365 PRO B N   1 
ATOM 6000 C CA  . PRO B 1 365 ? 48.987  52.288 16.980  1.00 0.43 ? 365 PRO B CA  1 
ATOM 6001 C C   . PRO B 1 365 ? 50.247  52.891 17.580  1.00 0.43 ? 365 PRO B C   1 
ATOM 6002 O O   . PRO B 1 365 ? 50.317  54.114 17.660  1.00 0.43 ? 365 PRO B O   1 
ATOM 6003 C CB  . PRO B 1 365 ? 47.835  52.492 17.993  1.00 0.43 ? 365 PRO B CB  1 
ATOM 6004 C CG  . PRO B 1 365 ? 46.995  51.221 17.901  1.00 0.43 ? 365 PRO B CG  1 
ATOM 6005 C CD  . PRO B 1 365 ? 48.048  50.161 17.615  1.00 0.43 ? 365 PRO B CD  1 
ATOM 6006 N N   . THR B 1 366 ? 51.192  52.094 18.116  1.00 0.29 ? 366 THR B N   1 
ATOM 6007 C CA  . THR B 1 366 ? 52.253  52.609 18.975  1.00 0.29 ? 366 THR B CA  1 
ATOM 6008 C C   . THR B 1 366 ? 53.627  52.604 18.323  1.00 0.29 ? 366 THR B C   1 
ATOM 6009 O O   . THR B 1 366 ? 54.553  53.197 18.880  1.00 0.29 ? 366 THR B O   1 
ATOM 6010 C CB  . THR B 1 366 ? 52.303  51.897 20.330  1.00 0.29 ? 366 THR B CB  1 
ATOM 6011 O OG1 . THR B 1 366 ? 52.194  50.494 20.199  1.00 0.29 ? 366 THR B OG1 1 
ATOM 6012 C CG2 . THR B 1 366 ? 51.076  52.291 21.167  1.00 0.29 ? 366 THR B CG2 1 
ATOM 6013 N N   . GLU B 1 367 ? 53.789  52.055 17.096  1.00 0.55 ? 367 GLU B N   1 
ATOM 6014 C CA  . GLU B 1 367 ? 55.020  52.191 16.333  1.00 0.55 ? 367 GLU B CA  1 
ATOM 6015 C C   . GLU B 1 367 ? 54.731  52.294 14.834  1.00 0.55 ? 367 GLU B C   1 
ATOM 6016 O O   . GLU B 1 367 ? 53.627  51.949 14.421  1.00 0.55 ? 367 GLU B O   1 
ATOM 6017 C CB  . GLU B 1 367 ? 56.042  51.055 16.627  1.00 0.55 ? 367 GLU B CB  1 
ATOM 6018 C CG  . GLU B 1 367 ? 55.643  49.621 16.189  1.00 0.55 ? 367 GLU B CG  1 
ATOM 6019 C CD  . GLU B 1 367 ? 56.800  48.622 16.324  1.00 0.55 ? 367 GLU B CD  1 
ATOM 6020 O OE1 . GLU B 1 367 ? 57.951  49.053 16.608  1.00 0.55 ? 367 GLU B OE1 1 
ATOM 6021 O OE2 . GLU B 1 367 ? 56.567  47.406 16.090  1.00 0.55 ? 367 GLU B OE2 1 
ATOM 6022 N N   . PRO B 1 368 ? 55.623  52.779 13.947  1.00 0.47 ? 368 PRO B N   1 
ATOM 6023 C CA  . PRO B 1 368 ? 55.251  53.064 12.556  1.00 0.47 ? 368 PRO B CA  1 
ATOM 6024 C C   . PRO B 1 368 ? 55.122  51.836 11.673  1.00 0.47 ? 368 PRO B C   1 
ATOM 6025 O O   . PRO B 1 368 ? 54.577  51.936 10.574  1.00 0.47 ? 368 PRO B O   1 
ATOM 6026 C CB  . PRO B 1 368 ? 56.413  53.929 12.022  1.00 0.47 ? 368 PRO B CB  1 
ATOM 6027 C CG  . PRO B 1 368 ? 57.055  54.537 13.268  1.00 0.47 ? 368 PRO B CG  1 
ATOM 6028 C CD  . PRO B 1 368 ? 56.879  53.437 14.311  1.00 0.47 ? 368 PRO B CD  1 
ATOM 6029 N N   . LYS B 1 369 ? 55.729  50.705 12.063  1.00 0.52 ? 369 LYS B N   1 
ATOM 6030 C CA  . LYS B 1 369 ? 55.805  49.519 11.238  1.00 0.52 ? 369 LYS B CA  1 
ATOM 6031 C C   . LYS B 1 369 ? 54.497  48.759 11.063  1.00 0.52 ? 369 LYS B C   1 
ATOM 6032 O O   . LYS B 1 369 ? 53.771  48.458 12.002  1.00 0.52 ? 369 LYS B O   1 
ATOM 6033 C CB  . LYS B 1 369 ? 56.907  48.556 11.738  1.00 0.52 ? 369 LYS B CB  1 
ATOM 6034 C CG  . LYS B 1 369 ? 58.307  49.183 11.660  1.00 0.52 ? 369 LYS B CG  1 
ATOM 6035 C CD  . LYS B 1 369 ? 59.420  48.225 12.113  1.00 0.52 ? 369 LYS B CD  1 
ATOM 6036 C CE  . LYS B 1 369 ? 60.807  48.865 12.021  1.00 0.52 ? 369 LYS B CE  1 
ATOM 6037 N NZ  . LYS B 1 369 ? 61.851  47.910 12.452  1.00 0.52 ? 369 LYS B NZ  1 
ATOM 6038 N N   . LYS B 1 370 ? 54.186  48.389 9.805   1.00 0.53 ? 370 LYS B N   1 
ATOM 6039 C CA  . LYS B 1 370 ? 53.081  47.505 9.504   1.00 0.53 ? 370 LYS B CA  1 
ATOM 6040 C C   . LYS B 1 370 ? 53.405  46.044 9.780   1.00 0.53 ? 370 LYS B C   1 
ATOM 6041 O O   . LYS B 1 370 ? 54.573  45.661 9.848   1.00 0.53 ? 370 LYS B O   1 
ATOM 6042 C CB  . LYS B 1 370 ? 52.659  47.650 8.020   1.00 0.53 ? 370 LYS B CB  1 
ATOM 6043 C CG  . LYS B 1 370 ? 53.702  47.150 6.997   1.00 0.53 ? 370 LYS B CG  1 
ATOM 6044 C CD  . LYS B 1 370 ? 53.295  47.401 5.532   1.00 0.53 ? 370 LYS B CD  1 
ATOM 6045 C CE  . LYS B 1 370 ? 52.019  46.656 5.114   1.00 0.53 ? 370 LYS B CE  1 
ATOM 6046 N NZ  . LYS B 1 370 ? 51.701  46.903 3.686   1.00 0.53 ? 370 LYS B NZ  1 
ATOM 6047 N N   . ASP B 1 371 ? 52.370  45.177 9.901   1.00 0.55 ? 371 ASP B N   1 
ATOM 6048 C CA  . ASP B 1 371 ? 52.546  43.744 10.015  1.00 0.55 ? 371 ASP B CA  1 
ATOM 6049 C C   . ASP B 1 371 ? 53.265  43.156 8.789   1.00 0.55 ? 371 ASP B C   1 
ATOM 6050 O O   . ASP B 1 371 ? 52.871  43.331 7.629   1.00 0.55 ? 371 ASP B O   1 
ATOM 6051 C CB  . ASP B 1 371 ? 51.182  43.067 10.329  1.00 0.55 ? 371 ASP B CB  1 
ATOM 6052 C CG  . ASP B 1 371 ? 51.312  41.566 10.550  1.00 0.55 ? 371 ASP B CG  1 
ATOM 6053 O OD1 . ASP B 1 371 ? 52.461  41.089 10.745  1.00 0.55 ? 371 ASP B OD1 1 
ATOM 6054 O OD2 . ASP B 1 371 ? 50.267  40.882 10.483  1.00 0.55 ? 371 ASP B OD2 1 
ATOM 6055 N N   . LYS B 1 372 ? 54.389  42.468 9.052   1.00 0.57 ? 372 LYS B N   1 
ATOM 6056 C CA  . LYS B 1 372 ? 55.168  41.775 8.060   1.00 0.57 ? 372 LYS B CA  1 
ATOM 6057 C C   . LYS B 1 372 ? 55.103  40.269 8.225   1.00 0.57 ? 372 LYS B C   1 
ATOM 6058 O O   . LYS B 1 372 ? 55.726  39.561 7.437   1.00 0.57 ? 372 LYS B O   1 
ATOM 6059 C CB  . LYS B 1 372 ? 56.649  42.214 8.162   1.00 0.57 ? 372 LYS B CB  1 
ATOM 6060 C CG  . LYS B 1 372 ? 56.901  43.712 7.899   1.00 0.57 ? 372 LYS B CG  1 
ATOM 6061 C CD  . LYS B 1 372 ? 56.542  44.181 6.478   1.00 0.57 ? 372 LYS B CD  1 
ATOM 6062 C CE  . LYS B 1 372 ? 57.383  43.489 5.400   1.00 0.57 ? 372 LYS B CE  1 
ATOM 6063 N NZ  . LYS B 1 372 ? 57.091  44.055 4.065   1.00 0.57 ? 372 LYS B NZ  1 
ATOM 6064 N N   . LYS B 1 373 ? 54.349  39.731 9.211   1.00 0.58 ? 373 LYS B N   1 
ATOM 6065 C CA  . LYS B 1 373 ? 54.309  38.305 9.496   1.00 0.58 ? 373 LYS B CA  1 
ATOM 6066 C C   . LYS B 1 373 ? 53.675  37.469 8.391   1.00 0.58 ? 373 LYS B C   1 
ATOM 6067 O O   . LYS B 1 373 ? 54.147  36.386 8.052   1.00 0.58 ? 373 LYS B O   1 
ATOM 6068 C CB  . LYS B 1 373 ? 53.552  38.061 10.825  1.00 0.58 ? 373 LYS B CB  1 
ATOM 6069 C CG  . LYS B 1 373 ? 53.736  36.654 11.421  1.00 0.58 ? 373 LYS B CG  1 
ATOM 6070 C CD  . LYS B 1 373 ? 52.804  36.420 12.624  1.00 0.58 ? 373 LYS B CD  1 
ATOM 6071 C CE  . LYS B 1 373 ? 52.884  35.012 13.219  1.00 0.58 ? 373 LYS B CE  1 
ATOM 6072 N NZ  . LYS B 1 373 ? 51.867  34.742 14.255  1.00 0.58 ? 373 LYS B NZ  1 
ATOM 6073 N N   . LYS B 1 374 ? 52.554  37.956 7.811   1.00 0.53 ? 374 LYS B N   1 
ATOM 6074 C CA  . LYS B 1 374 ? 51.846  37.343 6.690   1.00 0.53 ? 374 LYS B CA  1 
ATOM 6075 C C   . LYS B 1 374 ? 51.421  35.889 6.899   1.00 0.53 ? 374 LYS B C   1 
ATOM 6076 O O   . LYS B 1 374 ? 51.328  35.105 5.955   1.00 0.53 ? 374 LYS B O   1 
ATOM 6077 C CB  . LYS B 1 374 ? 52.618  37.503 5.351   1.00 0.53 ? 374 LYS B CB  1 
ATOM 6078 C CG  . LYS B 1 374 ? 52.851  38.972 4.960   1.00 0.53 ? 374 LYS B CG  1 
ATOM 6079 C CD  . LYS B 1 374 ? 53.601  39.149 3.625   1.00 0.53 ? 374 LYS B CD  1 
ATOM 6080 C CE  . LYS B 1 374 ? 52.811  38.654 2.406   1.00 0.53 ? 374 LYS B CE  1 
ATOM 6081 N NZ  . LYS B 1 374 ? 53.544  38.928 1.147   1.00 0.53 ? 374 LYS B NZ  1 
ATOM 6082 N N   . LYS B 1 375 ? 51.129  35.529 8.166   1.00 0.50 ? 375 LYS B N   1 
ATOM 6083 C CA  . LYS B 1 375 ? 50.811  34.190 8.631   1.00 0.50 ? 375 LYS B CA  1 
ATOM 6084 C C   . LYS B 1 375 ? 51.858  33.125 8.281   1.00 0.50 ? 375 LYS B C   1 
ATOM 6085 O O   . LYS B 1 375 ? 51.519  31.966 8.042   1.00 0.50 ? 375 LYS B O   1 
ATOM 6086 C CB  . LYS B 1 375 ? 49.390  33.748 8.191   1.00 0.50 ? 375 LYS B CB  1 
ATOM 6087 C CG  . LYS B 1 375 ? 48.283  34.695 8.679   1.00 0.50 ? 375 LYS B CG  1 
ATOM 6088 C CD  . LYS B 1 375 ? 46.871  34.286 8.223   1.00 0.50 ? 375 LYS B CD  1 
ATOM 6089 C CE  . LYS B 1 375 ? 46.399  32.961 8.829   1.00 0.50 ? 375 LYS B CE  1 
ATOM 6090 N NZ  . LYS B 1 375 ? 45.021  32.654 8.388   1.00 0.50 ? 375 LYS B NZ  1 
ATOM 6091 N N   . ALA B 1 376 ? 53.156  33.489 8.276   1.00 0.49 ? 376 ALA B N   1 
ATOM 6092 C CA  . ALA B 1 376 ? 54.211  32.627 7.804   1.00 0.49 ? 376 ALA B CA  1 
ATOM 6093 C C   . ALA B 1 376 ? 55.488  32.877 8.588   1.00 0.49 ? 376 ALA B C   1 
ATOM 6094 O O   . ALA B 1 376 ? 55.568  33.802 9.397   1.00 0.49 ? 376 ALA B O   1 
ATOM 6095 C CB  . ALA B 1 376 ? 54.445  32.906 6.309   1.00 0.49 ? 376 ALA B CB  1 
ATOM 6096 N N   . ASP B 1 377 ? 56.494  31.998 8.394   1.00 0.46 ? 377 ASP B N   1 
ATOM 6097 C CA  . ASP B 1 377 ? 57.852  32.086 8.916   1.00 0.46 ? 377 ASP B CA  1 
ATOM 6098 C C   . ASP B 1 377 ? 57.977  32.225 10.434  1.00 0.46 ? 377 ASP B C   1 
ATOM 6099 O O   . ASP B 1 377 ? 58.876  32.879 10.959  1.00 0.46 ? 377 ASP B O   1 
ATOM 6100 C CB  . ASP B 1 377 ? 58.671  33.157 8.152   1.00 0.46 ? 377 ASP B CB  1 
ATOM 6101 C CG  . ASP B 1 377 ? 58.709  32.865 6.658   1.00 0.46 ? 377 ASP B CG  1 
ATOM 6102 O OD1 . ASP B 1 377 ? 58.377  31.715 6.259   1.00 0.46 ? 377 ASP B OD1 1 
ATOM 6103 O OD2 . ASP B 1 377 ? 59.079  33.794 5.897   1.00 0.46 ? 377 ASP B OD2 1 
ATOM 6104 N N   . GLU B 1 378 ? 57.078  31.566 11.194  1.00 0.50 ? 378 GLU B N   1 
ATOM 6105 C CA  . GLU B 1 378 ? 57.112  31.537 12.641  1.00 0.50 ? 378 GLU B CA  1 
ATOM 6106 C C   . GLU B 1 378 ? 58.340  30.835 13.206  1.00 0.50 ? 378 GLU B C   1 
ATOM 6107 O O   . GLU B 1 378 ? 58.724  29.751 12.773  1.00 0.50 ? 378 GLU B O   1 
ATOM 6108 C CB  . GLU B 1 378 ? 55.814  30.909 13.211  1.00 0.50 ? 378 GLU B CB  1 
ATOM 6109 C CG  . GLU B 1 378 ? 54.547  31.715 12.826  1.00 0.50 ? 378 GLU B CG  1 
ATOM 6110 C CD  . GLU B 1 378 ? 53.281  31.247 13.547  1.00 0.50 ? 378 GLU B CD  1 
ATOM 6111 O OE1 . GLU B 1 378 ? 53.056  30.018 13.631  1.00 0.50 ? 378 GLU B OE1 1 
ATOM 6112 O OE2 . GLU B 1 378 ? 52.512  32.142 13.998  1.00 0.50 ? 378 GLU B OE2 1 
ATOM 6113 N N   . THR B 1 379 ? 58.990  31.439 14.224  1.00 0.49 ? 379 THR B N   1 
ATOM 6114 C CA  . THR B 1 379 ? 60.228  30.914 14.811  1.00 0.49 ? 379 THR B CA  1 
ATOM 6115 C C   . THR B 1 379 ? 60.074  29.595 15.544  1.00 0.49 ? 379 THR B C   1 
ATOM 6116 O O   . THR B 1 379 ? 61.014  28.811 15.635  1.00 0.49 ? 379 THR B O   1 
ATOM 6117 C CB  . THR B 1 379 ? 60.898  31.941 15.723  1.00 0.49 ? 379 THR B CB  1 
ATOM 6118 O OG1 . THR B 1 379 ? 61.239  33.079 14.952  1.00 0.49 ? 379 THR B OG1 1 
ATOM 6119 C CG2 . THR B 1 379 ? 62.225  31.488 16.349  1.00 0.49 ? 379 THR B CG2 1 
ATOM 6120 N N   . GLN B 1 380 ? 58.876  29.316 16.106  1.00 0.37 ? 380 GLN B N   1 
ATOM 6121 C CA  . GLN B 1 380 ? 58.572  28.104 16.860  1.00 0.37 ? 380 GLN B CA  1 
ATOM 6122 C C   . GLN B 1 380 ? 59.509  27.868 18.045  1.00 0.37 ? 380 GLN B C   1 
ATOM 6123 O O   . GLN B 1 380 ? 60.136  26.827 18.223  1.00 0.37 ? 380 GLN B O   1 
ATOM 6124 C CB  . GLN B 1 380 ? 58.401  26.874 15.931  1.00 0.37 ? 380 GLN B CB  1 
ATOM 6125 C CG  . GLN B 1 380 ? 57.754  25.616 16.567  1.00 0.37 ? 380 GLN B CG  1 
ATOM 6126 C CD  . GLN B 1 380 ? 56.305  25.833 17.001  1.00 0.37 ? 380 GLN B CD  1 
ATOM 6127 O OE1 . GLN B 1 380 ? 55.659  26.847 16.748  1.00 0.37 ? 380 GLN B OE1 1 
ATOM 6128 N NE2 . GLN B 1 380 ? 55.753  24.817 17.707  1.00 0.37 ? 380 GLN B NE2 1 
ATOM 6129 N N   . ALA B 1 381 ? 59.630  28.912 18.888  1.00 0.45 ? 381 ALA B N   1 
ATOM 6130 C CA  . ALA B 1 381 ? 60.499  28.950 20.042  1.00 0.45 ? 381 ALA B CA  1 
ATOM 6131 C C   . ALA B 1 381 ? 60.088  28.003 21.167  1.00 0.45 ? 381 ALA B C   1 
ATOM 6132 O O   . ALA B 1 381 ? 58.968  27.510 21.226  1.00 0.45 ? 381 ALA B O   1 
ATOM 6133 C CB  . ALA B 1 381 ? 60.593  30.404 20.558  1.00 0.45 ? 381 ALA B CB  1 
ATOM 6134 N N   . LEU B 1 382 ? 61.023  27.738 22.102  1.00 0.39 ? 382 LEU B N   1 
ATOM 6135 C CA  . LEU B 1 382 ? 60.856  26.794 23.198  1.00 0.39 ? 382 LEU B CA  1 
ATOM 6136 C C   . LEU B 1 382 ? 59.689  27.016 24.181  1.00 0.39 ? 382 LEU B C   1 
ATOM 6137 O O   . LEU B 1 382 ? 59.046  26.021 24.526  1.00 0.39 ? 382 LEU B O   1 
ATOM 6138 C CB  . LEU B 1 382 ? 62.205  26.722 23.968  1.00 0.39 ? 382 LEU B CB  1 
ATOM 6139 C CG  . LEU B 1 382 ? 62.293  25.698 25.121  1.00 0.39 ? 382 LEU B CG  1 
ATOM 6140 C CD1 . LEU B 1 382 ? 62.144  24.252 24.618  1.00 0.39 ? 382 LEU B CD1 1 
ATOM 6141 C CD2 . LEU B 1 382 ? 63.621  25.865 25.880  1.00 0.39 ? 382 LEU B CD2 1 
ATOM 6142 N N   . PRO B 1 383 ? 59.331  28.198 24.699  1.00 0.48 ? 383 PRO B N   1 
ATOM 6143 C CA  . PRO B 1 383 ? 58.249  28.297 25.670  1.00 0.48 ? 383 PRO B CA  1 
ATOM 6144 C C   . PRO B 1 383 ? 56.875  28.229 25.024  1.00 0.48 ? 383 PRO B C   1 
ATOM 6145 O O   . PRO B 1 383 ? 56.636  28.850 23.990  1.00 0.48 ? 383 PRO B O   1 
ATOM 6146 C CB  . PRO B 1 383 ? 58.475  29.652 26.362  1.00 0.48 ? 383 PRO B CB  1 
ATOM 6147 C CG  . PRO B 1 383 ? 59.253  30.476 25.335  1.00 0.48 ? 383 PRO B CG  1 
ATOM 6148 C CD  . PRO B 1 383 ? 60.115  29.428 24.635  1.00 0.48 ? 383 PRO B CD  1 
ATOM 6149 N N   . GLN B 1 384 ? 55.944  27.492 25.663  1.00 0.49 ? 384 GLN B N   1 
ATOM 6150 C CA  . GLN B 1 384 ? 54.591  27.282 25.193  1.00 0.49 ? 384 GLN B CA  1 
ATOM 6151 C C   . GLN B 1 384 ? 53.664  28.479 25.377  1.00 0.49 ? 384 GLN B C   1 
ATOM 6152 O O   . GLN B 1 384 ? 53.932  29.398 26.151  1.00 0.49 ? 384 GLN B O   1 
ATOM 6153 C CB  . GLN B 1 384 ? 53.968  26.047 25.907  1.00 0.49 ? 384 GLN B CB  1 
ATOM 6154 C CG  . GLN B 1 384 ? 53.735  26.228 27.436  1.00 0.49 ? 384 GLN B CG  1 
ATOM 6155 C CD  . GLN B 1 384 ? 53.080  25.012 28.101  1.00 0.49 ? 384 GLN B CD  1 
ATOM 6156 O OE1 . GLN B 1 384 ? 51.989  25.087 28.680  1.00 0.49 ? 384 GLN B OE1 1 
ATOM 6157 N NE2 . GLN B 1 384 ? 53.780  23.858 28.040  1.00 0.49 ? 384 GLN B NE2 1 
ATOM 6158 N N   . ARG B 1 385 ? 52.504  28.475 24.683  1.00 0.53 ? 385 ARG B N   1 
ATOM 6159 C CA  . ARG B 1 385 ? 51.454  29.453 24.895  1.00 0.53 ? 385 ARG B CA  1 
ATOM 6160 C C   . ARG B 1 385 ? 50.159  28.722 25.203  1.00 0.53 ? 385 ARG B C   1 
ATOM 6161 O O   . ARG B 1 385 ? 49.950  27.586 24.784  1.00 0.53 ? 385 ARG B O   1 
ATOM 6162 C CB  . ARG B 1 385 ? 51.290  30.407 23.683  1.00 0.53 ? 385 ARG B CB  1 
ATOM 6163 C CG  . ARG B 1 385 ? 50.480  31.687 23.988  1.00 0.53 ? 385 ARG B CG  1 
ATOM 6164 C CD  . ARG B 1 385 ? 50.384  32.703 22.842  1.00 0.53 ? 385 ARG B CD  1 
ATOM 6165 N NE  . ARG B 1 385 ? 49.456  32.138 21.812  1.00 0.53 ? 385 ARG B NE  1 
ATOM 6166 C CZ  . ARG B 1 385 ? 49.210  32.740 20.639  1.00 0.53 ? 385 ARG B CZ  1 
ATOM 6167 N NH1 . ARG B 1 385 ? 48.454  32.093 19.755  1.00 0.53 ? 385 ARG B NH1 1 
ATOM 6168 N NH2 . ARG B 1 385 ? 49.683  33.937 20.334  1.00 0.53 ? 385 ARG B NH2 1 
ATOM 6169 N N   . GLN B 1 386 ? 49.262  29.356 25.987  1.00 0.61 ? 386 GLN B N   1 
ATOM 6170 C CA  . GLN B 1 386 ? 48.032  28.776 26.496  1.00 0.61 ? 386 GLN B CA  1 
ATOM 6171 C C   . GLN B 1 386 ? 46.944  28.499 25.466  1.00 0.61 ? 386 GLN B C   1 
ATOM 6172 O O   . GLN B 1 386 ? 46.083  27.649 25.679  1.00 0.61 ? 386 GLN B O   1 
ATOM 6173 C CB  . GLN B 1 386 ? 47.487  29.725 27.587  1.00 0.61 ? 386 GLN B CB  1 
ATOM 6174 C CG  . GLN B 1 386 ? 46.278  29.206 28.406  1.00 0.61 ? 386 GLN B CG  1 
ATOM 6175 C CD  . GLN B 1 386 ? 46.006  30.163 29.572  1.00 0.61 ? 386 GLN B CD  1 
ATOM 6176 O OE1 . GLN B 1 386 ? 46.779  31.103 29.779  1.00 0.61 ? 386 GLN B OE1 1 
ATOM 6177 N NE2 . GLN B 1 386 ? 44.919  29.909 30.331  1.00 0.61 ? 386 GLN B NE2 1 
ATOM 6178 N N   . LYS B 1 387 ? 46.949  29.197 24.315  1.00 0.56 ? 387 LYS B N   1 
ATOM 6179 C CA  . LYS B 1 387 ? 45.868  29.091 23.360  1.00 0.56 ? 387 LYS B CA  1 
ATOM 6180 C C   . LYS B 1 387 ? 46.363  29.291 21.940  1.00 0.56 ? 387 LYS B C   1 
ATOM 6181 O O   . LYS B 1 387 ? 47.394  29.923 21.693  1.00 0.56 ? 387 LYS B O   1 
ATOM 6182 C CB  . LYS B 1 387 ? 44.730  30.084 23.706  1.00 0.56 ? 387 LYS B CB  1 
ATOM 6183 C CG  . LYS B 1 387 ? 45.121  31.568 23.623  1.00 0.56 ? 387 LYS B CG  1 
ATOM 6184 C CD  . LYS B 1 387 ? 44.212  32.478 24.465  1.00 0.56 ? 387 LYS B CD  1 
ATOM 6185 C CE  . LYS B 1 387 ? 42.719  32.397 24.123  1.00 0.56 ? 387 LYS B CE  1 
ATOM 6186 N NZ  . LYS B 1 387 ? 41.985  33.438 24.872  1.00 0.56 ? 387 LYS B NZ  1 
ATOM 6187 N N   . LYS B 1 388 ? 45.648  28.686 20.968  1.00 0.48 ? 388 LYS B N   1 
ATOM 6188 C CA  . LYS B 1 388 ? 46.032  28.671 19.570  1.00 0.48 ? 388 LYS B CA  1 
ATOM 6189 C C   . LYS B 1 388 ? 45.786  29.976 18.824  1.00 0.48 ? 388 LYS B C   1 
ATOM 6190 O O   . LYS B 1 388 ? 46.674  30.451 18.128  1.00 0.48 ? 388 LYS B O   1 
ATOM 6191 C CB  . LYS B 1 388 ? 45.331  27.502 18.833  1.00 0.48 ? 388 LYS B CB  1 
ATOM 6192 C CG  . LYS B 1 388 ? 45.575  26.105 19.443  1.00 0.48 ? 388 LYS B CG  1 
ATOM 6193 C CD  . LYS B 1 388 ? 47.042  25.632 19.405  1.00 0.48 ? 388 LYS B CD  1 
ATOM 6194 C CE  . LYS B 1 388 ? 47.202  24.191 19.909  1.00 0.48 ? 388 LYS B CE  1 
ATOM 6195 N NZ  . LYS B 1 388 ? 48.618  23.759 19.857  1.00 0.48 ? 388 LYS B NZ  1 
ATOM 6196 N N   . GLN B 1 389 ? 44.604  30.611 18.974  1.00 0.50 ? 389 GLN B N   1 
ATOM 6197 C CA  . GLN B 1 389 ? 44.267  31.810 18.226  1.00 0.50 ? 389 GLN B CA  1 
ATOM 6198 C C   . GLN B 1 389 ? 43.285  32.652 19.027  1.00 0.50 ? 389 GLN B C   1 
ATOM 6199 O O   . GLN B 1 389 ? 42.498  32.112 19.803  1.00 0.50 ? 389 GLN B O   1 
ATOM 6200 C CB  . GLN B 1 389 ? 43.651  31.408 16.850  1.00 0.50 ? 389 GLN B CB  1 
ATOM 6201 C CG  . GLN B 1 389 ? 43.031  32.522 15.963  1.00 0.50 ? 389 GLN B CG  1 
ATOM 6202 C CD  . GLN B 1 389 ? 44.043  33.580 15.525  1.00 0.50 ? 389 GLN B CD  1 
ATOM 6203 O OE1 . GLN B 1 389 ? 45.164  33.669 16.020  1.00 0.50 ? 389 GLN B OE1 1 
ATOM 6204 N NE2 . GLN B 1 389 ? 43.625  34.448 14.576  1.00 0.50 ? 389 GLN B NE2 1 
ATOM 6205 N N   . GLN B 1 390 ? 43.311  34.002 18.879  1.00 0.57 ? 390 GLN B N   1 
ATOM 6206 C CA  . GLN B 1 390 ? 42.267  34.864 19.416  1.00 0.57 ? 390 GLN B CA  1 
ATOM 6207 C C   . GLN B 1 390 ? 42.207  36.196 18.673  1.00 0.57 ? 390 GLN B C   1 
ATOM 6208 O O   . GLN B 1 390 ? 43.226  36.702 18.212  1.00 0.57 ? 390 GLN B O   1 
ATOM 6209 C CB  . GLN B 1 390 ? 42.460  35.152 20.933  1.00 0.57 ? 390 GLN B CB  1 
ATOM 6210 C CG  . GLN B 1 390 ? 43.796  35.848 21.301  1.00 0.57 ? 390 GLN B CG  1 
ATOM 6211 C CD  . GLN B 1 390 ? 44.019  35.887 22.813  1.00 0.57 ? 390 GLN B CD  1 
ATOM 6212 O OE1 . GLN B 1 390 ? 43.136  35.579 23.617  1.00 0.57 ? 390 GLN B OE1 1 
ATOM 6213 N NE2 . GLN B 1 390 ? 45.257  36.255 23.220  1.00 0.57 ? 390 GLN B NE2 1 
ATOM 6214 N N   . THR B 1 391 ? 41.013  36.823 18.556  1.00 0.54 ? 391 THR B N   1 
ATOM 6215 C CA  . THR B 1 391 ? 40.875  38.192 18.051  1.00 0.54 ? 391 THR B CA  1 
ATOM 6216 C C   . THR B 1 391 ? 39.650  38.813 18.698  1.00 0.54 ? 391 THR B C   1 
ATOM 6217 O O   . THR B 1 391 ? 38.666  38.123 18.950  1.00 0.54 ? 391 THR B O   1 
ATOM 6218 C CB  . THR B 1 391 ? 40.814  38.337 16.518  1.00 0.54 ? 391 THR B CB  1 
ATOM 6219 O OG1 . THR B 1 391 ? 40.581  39.680 16.103  1.00 0.54 ? 391 THR B OG1 1 
ATOM 6220 C CG2 . THR B 1 391 ? 39.706  37.486 15.884  1.00 0.54 ? 391 THR B CG2 1 
ATOM 6221 N N   . VAL B 1 392 ? 39.700  40.126 19.018  1.00 0.52 ? 392 VAL B N   1 
ATOM 6222 C CA  . VAL B 1 392 ? 38.631  40.905 19.625  1.00 0.52 ? 392 VAL B CA  1 
ATOM 6223 C C   . VAL B 1 392 ? 38.833  42.284 19.034  1.00 0.52 ? 392 VAL B C   1 
ATOM 6224 O O   . VAL B 1 392 ? 39.980  42.651 18.789  1.00 0.52 ? 392 VAL B O   1 
ATOM 6225 C CB  . VAL B 1 392 ? 38.725  41.003 21.155  1.00 0.52 ? 392 VAL B CB  1 
ATOM 6226 C CG1 . VAL B 1 392 ? 37.718  42.006 21.760  1.00 0.52 ? 392 VAL B CG1 1 
ATOM 6227 C CG2 . VAL B 1 392 ? 38.487  39.614 21.774  1.00 0.52 ? 392 VAL B CG2 1 
ATOM 6228 N N   . THR B 1 393 ? 37.750  43.045 18.723  1.00 0.46 ? 393 THR B N   1 
ATOM 6229 C CA  . THR B 1 393 ? 37.775  44.421 18.185  1.00 0.46 ? 393 THR B CA  1 
ATOM 6230 C C   . THR B 1 393 ? 38.620  44.602 16.933  1.00 0.46 ? 393 THR B C   1 
ATOM 6231 O O   . THR B 1 393 ? 39.168  45.670 16.666  1.00 0.46 ? 393 THR B O   1 
ATOM 6232 C CB  . THR B 1 393 ? 38.048  45.552 19.193  1.00 0.46 ? 393 THR B CB  1 
ATOM 6233 O OG1 . THR B 1 393 ? 39.179  45.313 20.017  1.00 0.46 ? 393 THR B OG1 1 
ATOM 6234 C CG2 . THR B 1 393 ? 36.860  45.717 20.148  1.00 0.46 ? 393 THR B CG2 1 
ATOM 6235 N N   . LEU B 1 394 ? 38.696  43.528 16.117  1.00 0.41 ? 394 LEU B N   1 
ATOM 6236 C CA  . LEU B 1 394 ? 39.483  43.403 14.901  1.00 0.41 ? 394 LEU B CA  1 
ATOM 6237 C C   . LEU B 1 394 ? 40.992  43.529 15.120  1.00 0.41 ? 394 LEU B C   1 
ATOM 6238 O O   . LEU B 1 394 ? 41.758  43.814 14.201  1.00 0.41 ? 394 LEU B O   1 
ATOM 6239 C CB  . LEU B 1 394 ? 38.978  44.286 13.727  1.00 0.41 ? 394 LEU B CB  1 
ATOM 6240 C CG  . LEU B 1 394 ? 37.585  43.917 13.162  1.00 0.41 ? 394 LEU B CG  1 
ATOM 6241 C CD1 . LEU B 1 394 ? 36.405  44.451 13.994  1.00 0.41 ? 394 LEU B CD1 1 
ATOM 6242 C CD2 . LEU B 1 394 ? 37.453  44.432 11.720  1.00 0.41 ? 394 LEU B CD2 1 
ATOM 6243 N N   . LEU B 1 395 ? 41.475  43.258 16.351  1.00 0.53 ? 395 LEU B N   1 
ATOM 6244 C CA  . LEU B 1 395 ? 42.884  43.225 16.691  1.00 0.53 ? 395 LEU B CA  1 
ATOM 6245 C C   . LEU B 1 395 ? 43.632  42.124 15.927  1.00 0.53 ? 395 LEU B C   1 
ATOM 6246 O O   . LEU B 1 395 ? 43.167  40.982 15.943  1.00 0.53 ? 395 LEU B O   1 
ATOM 6247 C CB  . LEU B 1 395 ? 42.996  43.032 18.229  1.00 0.53 ? 395 LEU B CB  1 
ATOM 6248 C CG  . LEU B 1 395 ? 44.363  43.229 18.922  1.00 0.53 ? 395 LEU B CG  1 
ATOM 6249 C CD1 . LEU B 1 395 ? 44.145  43.431 20.434  1.00 0.53 ? 395 LEU B CD1 1 
ATOM 6250 C CD2 . LEU B 1 395 ? 45.367  42.077 18.730  1.00 0.53 ? 395 LEU B CD2 1 
ATOM 6251 N N   . PRO B 1 396 ? 44.775  42.334 15.272  1.00 0.57 ? 396 PRO B N   1 
ATOM 6252 C CA  . PRO B 1 396 ? 45.373  41.332 14.391  1.00 0.57 ? 396 PRO B CA  1 
ATOM 6253 C C   . PRO B 1 396 ? 46.204  40.316 15.167  1.00 0.57 ? 396 PRO B C   1 
ATOM 6254 O O   . PRO B 1 396 ? 47.408  40.225 14.959  1.00 0.57 ? 396 PRO B O   1 
ATOM 6255 C CB  . PRO B 1 396 ? 46.241  42.186 13.446  1.00 0.57 ? 396 PRO B CB  1 
ATOM 6256 C CG  . PRO B 1 396 ? 46.660  43.383 14.299  1.00 0.57 ? 396 PRO B CG  1 
ATOM 6257 C CD  . PRO B 1 396 ? 45.413  43.643 15.137  1.00 0.57 ? 396 PRO B CD  1 
ATOM 6258 N N   . ALA B 1 397 ? 45.569  39.574 16.103  1.00 0.64 ? 397 ALA B N   1 
ATOM 6259 C CA  . ALA B 1 397 ? 46.053  38.370 16.767  1.00 0.64 ? 397 ALA B CA  1 
ATOM 6260 C C   . ALA B 1 397 ? 47.450  38.403 17.392  1.00 0.64 ? 397 ALA B C   1 
ATOM 6261 O O   . ALA B 1 397 ? 48.070  37.367 17.614  1.00 0.64 ? 397 ALA B O   1 
ATOM 6262 C CB  . ALA B 1 397 ? 45.874  37.183 15.804  1.00 0.64 ? 397 ALA B CB  1 
ATOM 6263 N N   . ALA B 1 398 ? 47.943  39.615 17.730  1.00 0.70 ? 398 ALA B N   1 
ATOM 6264 C CA  . ALA B 1 398 ? 49.308  39.890 18.145  1.00 0.70 ? 398 ALA B CA  1 
ATOM 6265 C C   . ALA B 1 398 ? 50.381  39.501 17.105  1.00 0.70 ? 398 ALA B C   1 
ATOM 6266 O O   . ALA B 1 398 ? 51.548  39.319 17.430  1.00 0.70 ? 398 ALA B O   1 
ATOM 6267 C CB  . ALA B 1 398 ? 49.578  39.332 19.562  1.00 0.70 ? 398 ALA B CB  1 
ATOM 6268 N N   . ASP B 1 399 ? 50.042  39.427 15.793  1.00 0.63 ? 399 ASP B N   1 
ATOM 6269 C CA  . ASP B 1 399 ? 50.957  39.018 14.734  1.00 0.63 ? 399 ASP B CA  1 
ATOM 6270 C C   . ASP B 1 399 ? 52.151  39.961 14.544  1.00 0.63 ? 399 ASP B C   1 
ATOM 6271 O O   . ASP B 1 399 ? 53.298  39.538 14.369  1.00 0.63 ? 399 ASP B O   1 
ATOM 6272 C CB  . ASP B 1 399 ? 50.190  38.845 13.390  1.00 0.63 ? 399 ASP B CB  1 
ATOM 6273 C CG  . ASP B 1 399 ? 49.419  37.529 13.310  1.00 0.63 ? 399 ASP B CG  1 
ATOM 6274 O OD1 . ASP B 1 399 ? 49.939  36.499 13.821  1.00 0.63 ? 399 ASP B OD1 1 
ATOM 6275 O OD2 . ASP B 1 399 ? 48.340  37.496 12.665  1.00 0.63 ? 399 ASP B OD2 1 
ATOM 6276 N N   . LEU B 1 400 ? 51.911  41.286 14.639  1.00 0.65 ? 400 LEU B N   1 
ATOM 6277 C CA  . LEU B 1 400 ? 52.951  42.304 14.644  1.00 0.65 ? 400 LEU B CA  1 
ATOM 6278 C C   . LEU B 1 400 ? 53.895  42.139 15.833  1.00 0.65 ? 400 LEU B C   1 
ATOM 6279 O O   . LEU B 1 400 ? 55.116  42.201 15.677  1.00 0.65 ? 400 LEU B O   1 
ATOM 6280 C CB  . LEU B 1 400 ? 52.333  43.727 14.609  1.00 0.65 ? 400 LEU B CB  1 
ATOM 6281 C CG  . LEU B 1 400 ? 53.329  44.914 14.616  1.00 0.65 ? 400 LEU B CG  1 
ATOM 6282 C CD1 . LEU B 1 400 ? 54.331  44.887 13.450  1.00 0.65 ? 400 LEU B CD1 1 
ATOM 6283 C CD2 . LEU B 1 400 ? 52.571  46.251 14.615  1.00 0.65 ? 400 LEU B CD2 1 
ATOM 6284 N N   . ASP B 1 401 ? 53.347  41.844 17.035  1.00 0.71 ? 401 ASP B N   1 
ATOM 6285 C CA  . ASP B 1 401 ? 54.083  41.504 18.234  1.00 0.71 ? 401 ASP B CA  1 
ATOM 6286 C C   . ASP B 1 401 ? 54.919  40.242 18.059  1.00 0.71 ? 401 ASP B C   1 
ATOM 6287 O O   . ASP B 1 401 ? 56.107  40.233 18.374  1.00 0.71 ? 401 ASP B O   1 
ATOM 6288 C CB  . ASP B 1 401 ? 53.112  41.340 19.428  1.00 0.71 ? 401 ASP B CB  1 
ATOM 6289 C CG  . ASP B 1 401 ? 52.341  42.630 19.618  1.00 0.71 ? 401 ASP B CG  1 
ATOM 6290 O OD1 . ASP B 1 401 ? 52.987  43.568 20.153  1.00 0.71 ? 401 ASP B OD1 1 
ATOM 6291 O OD2 . ASP B 1 401 ? 51.143  42.702 19.236  1.00 0.71 ? 401 ASP B OD2 1 
ATOM 6292 N N   . ASP B 1 402 ? 54.359  39.165 17.466  1.00 0.68 ? 402 ASP B N   1 
ATOM 6293 C CA  . ASP B 1 402 ? 55.112  37.964 17.150  1.00 0.68 ? 402 ASP B CA  1 
ATOM 6294 C C   . ASP B 1 402 ? 56.306  38.229 16.252  1.00 0.68 ? 402 ASP B C   1 
ATOM 6295 O O   . ASP B 1 402 ? 57.422  37.819 16.558  1.00 0.68 ? 402 ASP B O   1 
ATOM 6296 C CB  . ASP B 1 402 ? 54.251  36.924 16.392  1.00 0.68 ? 402 ASP B CB  1 
ATOM 6297 C CG  . ASP B 1 402 ? 53.329  36.138 17.300  1.00 0.68 ? 402 ASP B CG  1 
ATOM 6298 O OD1 . ASP B 1 402 ? 53.578  36.090 18.527  1.00 0.68 ? 402 ASP B OD1 1 
ATOM 6299 O OD2 . ASP B 1 402 ? 52.457  35.450 16.709  1.00 0.68 ? 402 ASP B OD2 1 
ATOM 6300 N N   . PHE B 1 403 ? 56.110  38.973 15.145  1.00 0.67 ? 403 PHE B N   1 
ATOM 6301 C CA  . PHE B 1 403 ? 57.175  39.380 14.248  1.00 0.67 ? 403 PHE B CA  1 
ATOM 6302 C C   . PHE B 1 403 ? 58.227  40.245 14.949  1.00 0.67 ? 403 PHE B C   1 
ATOM 6303 O O   . PHE B 1 403 ? 59.421  39.947 14.908  1.00 0.67 ? 403 PHE B O   1 
ATOM 6304 C CB  . PHE B 1 403 ? 56.538  40.140 13.042  1.00 0.67 ? 403 PHE B CB  1 
ATOM 6305 C CG  . PHE B 1 403 ? 57.535  40.792 12.112  1.00 0.67 ? 403 PHE B CG  1 
ATOM 6306 C CD1 . PHE B 1 403 ? 58.276  40.030 11.198  1.00 0.67 ? 403 PHE B CD1 1 
ATOM 6307 C CD2 . PHE B 1 403 ? 57.766  42.177 12.181  1.00 0.67 ? 403 PHE B CD2 1 
ATOM 6308 C CE1 . PHE B 1 403 ? 59.234  40.636 10.375  1.00 0.67 ? 403 PHE B CE1 1 
ATOM 6309 C CE2 . PHE B 1 403 ? 58.724  42.786 11.362  1.00 0.67 ? 403 PHE B CE2 1 
ATOM 6310 C CZ  . PHE B 1 403 ? 59.458  42.015 10.455  1.00 0.67 ? 403 PHE B CZ  1 
ATOM 6311 N N   . SER B 1 404 ? 57.810  41.318 15.653  1.00 0.72 ? 404 SER B N   1 
ATOM 6312 C CA  . SER B 1 404 ? 58.730  42.250 16.293  1.00 0.72 ? 404 SER B CA  1 
ATOM 6313 C C   . SER B 1 404 ? 59.525  41.656 17.435  1.00 0.72 ? 404 SER B C   1 
ATOM 6314 O O   . SER B 1 404 ? 60.743  41.812 17.493  1.00 0.72 ? 404 SER B O   1 
ATOM 6315 C CB  . SER B 1 404 ? 58.033  43.549 16.770  1.00 0.72 ? 404 SER B CB  1 
ATOM 6316 O OG  . SER B 1 404 ? 57.073  43.318 17.797  1.00 0.72 ? 404 SER B OG  1 
ATOM 6317 N N   . LYS B 1 405 ? 58.874  40.902 18.344  1.00 0.72 ? 405 LYS B N   1 
ATOM 6318 C CA  . LYS B 1 405 ? 59.530  40.229 19.447  1.00 0.72 ? 405 LYS B CA  1 
ATOM 6319 C C   . LYS B 1 405 ? 60.445  39.100 19.001  1.00 0.72 ? 405 LYS B C   1 
ATOM 6320 O O   . LYS B 1 405 ? 61.519  38.912 19.567  1.00 0.72 ? 405 LYS B O   1 
ATOM 6321 C CB  . LYS B 1 405 ? 58.555  39.718 20.538  1.00 0.72 ? 405 LYS B CB  1 
ATOM 6322 C CG  . LYS B 1 405 ? 58.057  40.819 21.497  1.00 0.72 ? 405 LYS B CG  1 
ATOM 6323 C CD  . LYS B 1 405 ? 56.712  41.470 21.105  1.00 0.72 ? 405 LYS B CD  1 
ATOM 6324 C CE  . LYS B 1 405 ? 56.223  42.509 22.127  1.00 0.72 ? 405 LYS B CE  1 
ATOM 6325 N NZ  . LYS B 1 405 ? 54.795  42.884 22.001  1.00 0.72 ? 405 LYS B NZ  1 
ATOM 6326 N N   . GLN B 1 406 ? 60.062  38.315 17.969  1.00 0.67 ? 406 GLN B N   1 
ATOM 6327 C CA  . GLN B 1 406 ? 60.947  37.315 17.388  1.00 0.67 ? 406 GLN B CA  1 
ATOM 6328 C C   . GLN B 1 406 ? 62.176  37.934 16.734  1.00 0.67 ? 406 GLN B C   1 
ATOM 6329 O O   . GLN B 1 406 ? 63.292  37.482 16.971  1.00 0.67 ? 406 GLN B O   1 
ATOM 6330 C CB  . GLN B 1 406 ? 60.189  36.362 16.425  1.00 0.67 ? 406 GLN B CB  1 
ATOM 6331 C CG  . GLN B 1 406 ? 59.208  35.434 17.197  1.00 0.67 ? 406 GLN B CG  1 
ATOM 6332 C CD  . GLN B 1 406 ? 58.247  34.634 16.305  1.00 0.67 ? 406 GLN B CD  1 
ATOM 6333 O OE1 . GLN B 1 406 ? 58.528  34.245 15.174  1.00 0.67 ? 406 GLN B OE1 1 
ATOM 6334 N NE2 . GLN B 1 406 ? 57.050  34.307 16.851  1.00 0.67 ? 406 GLN B NE2 1 
ATOM 6335 N N   . LEU B 1 407 ? 62.033  39.033 15.963  1.00 0.71 ? 407 LEU B N   1 
ATOM 6336 C CA  . LEU B 1 407 ? 63.177  39.773 15.454  1.00 0.71 ? 407 LEU B CA  1 
ATOM 6337 C C   . LEU B 1 407 ? 64.050  40.374 16.542  1.00 0.71 ? 407 LEU B C   1 
ATOM 6338 O O   . LEU B 1 407 ? 65.275  40.311 16.464  1.00 0.71 ? 407 LEU B O   1 
ATOM 6339 C CB  . LEU B 1 407 ? 62.742  40.920 14.511  1.00 0.71 ? 407 LEU B CB  1 
ATOM 6340 C CG  . LEU B 1 407 ? 62.782  40.558 13.015  1.00 0.71 ? 407 LEU B CG  1 
ATOM 6341 C CD1 . LEU B 1 407 ? 61.794  39.444 12.641  1.00 0.71 ? 407 LEU B CD1 1 
ATOM 6342 C CD2 . LEU B 1 407 ? 62.516  41.815 12.172  1.00 0.71 ? 407 LEU B CD2 1 
ATOM 6343 N N   . GLN B 1 408 ? 63.432  40.970 17.582  1.00 0.70 ? 408 GLN B N   1 
ATOM 6344 C CA  . GLN B 1 408 ? 64.130  41.550 18.711  1.00 0.70 ? 408 GLN B CA  1 
ATOM 6345 C C   . GLN B 1 408 ? 64.952  40.545 19.495  1.00 0.70 ? 408 GLN B C   1 
ATOM 6346 O O   . GLN B 1 408 ? 66.111  40.818 19.796  1.00 0.70 ? 408 GLN B O   1 
ATOM 6347 C CB  . GLN B 1 408 ? 63.145  42.255 19.669  1.00 0.70 ? 408 GLN B CB  1 
ATOM 6348 C CG  . GLN B 1 408 ? 63.811  42.956 20.877  1.00 0.70 ? 408 GLN B CG  1 
ATOM 6349 C CD  . GLN B 1 408 ? 62.778  43.734 21.690  1.00 0.70 ? 408 GLN B CD  1 
ATOM 6350 O OE1 . GLN B 1 408 ? 61.579  43.719 21.420  1.00 0.70 ? 408 GLN B OE1 1 
ATOM 6351 N NE2 . GLN B 1 408 ? 63.266  44.458 22.725  1.00 0.70 ? 408 GLN B NE2 1 
ATOM 6352 N N   . GLN B 1 409 ? 64.390  39.352 19.795  1.00 0.68 ? 409 GLN B N   1 
ATOM 6353 C CA  . GLN B 1 409 ? 65.117  38.244 20.402  1.00 0.68 ? 409 GLN B CA  1 
ATOM 6354 C C   . GLN B 1 409 ? 66.237  37.732 19.500  1.00 0.68 ? 409 GLN B C   1 
ATOM 6355 O O   . GLN B 1 409 ? 67.361  37.522 19.940  1.00 0.68 ? 409 GLN B O   1 
ATOM 6356 C CB  . GLN B 1 409 ? 64.141  37.108 20.823  1.00 0.68 ? 409 GLN B CB  1 
ATOM 6357 C CG  . GLN B 1 409 ? 64.735  36.041 21.785  1.00 0.68 ? 409 GLN B CG  1 
ATOM 6358 C CD  . GLN B 1 409 ? 65.549  34.944 21.089  1.00 0.68 ? 409 GLN B CD  1 
ATOM 6359 O OE1 . GLN B 1 409 ? 65.133  34.406 20.059  1.00 0.68 ? 409 GLN B OE1 1 
ATOM 6360 N NE2 . GLN B 1 409 ? 66.686  34.537 21.685  1.00 0.68 ? 409 GLN B NE2 1 
ATOM 6361 N N   . SER B 1 410 ? 65.990  37.572 18.181  1.00 0.66 ? 410 SER B N   1 
ATOM 6362 C CA  . SER B 1 410 ? 67.017  37.133 17.238  1.00 0.66 ? 410 SER B CA  1 
ATOM 6363 C C   . SER B 1 410 ? 68.211  38.056 17.092  1.00 0.66 ? 410 SER B C   1 
ATOM 6364 O O   . SER B 1 410 ? 69.349  37.604 17.002  1.00 0.66 ? 410 SER B O   1 
ATOM 6365 C CB  . SER B 1 410 ? 66.486  36.967 15.794  1.00 0.66 ? 410 SER B CB  1 
ATOM 6366 O OG  . SER B 1 410 ? 65.536  35.907 15.701  1.00 0.66 ? 410 SER B OG  1 
ATOM 6367 N N   . MET B 1 411 ? 68.000  39.387 17.015  1.00 0.61 ? 411 MET B N   1 
ATOM 6368 C CA  . MET B 1 411 ? 69.101  40.336 16.989  1.00 0.61 ? 411 MET B CA  1 
ATOM 6369 C C   . MET B 1 411 ? 69.831  40.443 18.319  1.00 0.61 ? 411 MET B C   1 
ATOM 6370 O O   . MET B 1 411 ? 71.057  40.424 18.361  1.00 0.61 ? 411 MET B O   1 
ATOM 6371 C CB  . MET B 1 411 ? 68.680  41.731 16.450  1.00 0.61 ? 411 MET B CB  1 
ATOM 6372 C CG  . MET B 1 411 ? 67.751  42.551 17.364  1.00 0.61 ? 411 MET B CG  1 
ATOM 6373 S SD  . MET B 1 411 ? 67.171  44.130 16.669  1.00 0.61 ? 411 MET B SD  1 
ATOM 6374 C CE  . MET B 1 411 ? 66.001  43.450 15.462  1.00 0.61 ? 411 MET B CE  1 
ATOM 6375 N N   . SER B 1 412 ? 69.113  40.484 19.466  1.00 0.63 ? 412 SER B N   1 
ATOM 6376 C CA  . SER B 1 412 ? 69.739  40.542 20.778  1.00 0.63 ? 412 SER B CA  1 
ATOM 6377 C C   . SER B 1 412 ? 70.546  39.295 21.105  1.00 0.63 ? 412 SER B C   1 
ATOM 6378 O O   . SER B 1 412 ? 71.600  39.405 21.717  1.00 0.63 ? 412 SER B O   1 
ATOM 6379 C CB  . SER B 1 412 ? 68.754  40.876 21.932  1.00 0.63 ? 412 SER B CB  1 
ATOM 6380 O OG  . SER B 1 412 ? 67.719  39.903 22.023  1.00 0.63 ? 412 SER B OG  1 
ATOM 6381 N N   . SER B 1 413 ? 70.128  38.092 20.646  1.00 0.58 ? 413 SER B N   1 
ATOM 6382 C CA  . SER B 1 413 ? 70.893  36.861 20.826  1.00 0.58 ? 413 SER B CA  1 
ATOM 6383 C C   . SER B 1 413 ? 71.994  36.665 19.793  1.00 0.58 ? 413 SER B C   1 
ATOM 6384 O O   . SER B 1 413 ? 72.773  35.714 19.860  1.00 0.58 ? 413 SER B O   1 
ATOM 6385 C CB  . SER B 1 413 ? 70.002  35.589 20.841  1.00 0.58 ? 413 SER B CB  1 
ATOM 6386 O OG  . SER B 1 413 ? 69.400  35.284 19.577  1.00 0.58 ? 413 SER B OG  1 
ATOM 6387 N N   . ALA B 1 414 ? 72.115  37.583 18.811  1.00 0.51 ? 414 ALA B N   1 
ATOM 6388 C CA  . ALA B 1 414 ? 73.298  37.723 17.993  1.00 0.51 ? 414 ALA B CA  1 
ATOM 6389 C C   . ALA B 1 414 ? 74.295  38.700 18.620  1.00 0.51 ? 414 ALA B C   1 
ATOM 6390 O O   . ALA B 1 414 ? 75.500  38.450 18.634  1.00 0.51 ? 414 ALA B O   1 
ATOM 6391 C CB  . ALA B 1 414 ? 72.906  38.179 16.576  1.00 0.51 ? 414 ALA B CB  1 
ATOM 6392 N N   . ASP B 1 415 ? 73.796  39.819 19.191  1.00 0.45 ? 415 ASP B N   1 
ATOM 6393 C CA  . ASP B 1 415 ? 74.592  40.837 19.855  1.00 0.45 ? 415 ASP B CA  1 
ATOM 6394 C C   . ASP B 1 415 ? 75.070  40.415 21.255  1.00 0.45 ? 415 ASP B C   1 
ATOM 6395 O O   . ASP B 1 415 ? 76.006  40.981 21.821  1.00 0.45 ? 415 ASP B O   1 
ATOM 6396 C CB  . ASP B 1 415 ? 73.750  42.135 20.005  1.00 0.45 ? 415 ASP B CB  1 
ATOM 6397 C CG  . ASP B 1 415 ? 73.414  42.798 18.675  1.00 0.45 ? 415 ASP B CG  1 
ATOM 6398 O OD1 . ASP B 1 415 ? 74.069  42.494 17.649  1.00 0.45 ? 415 ASP B OD1 1 
ATOM 6399 O OD2 . ASP B 1 415 ? 72.502  43.668 18.704  1.00 0.45 ? 415 ASP B OD2 1 
ATOM 6400 N N   . SER B 1 416 ? 74.437  39.395 21.868  1.00 0.47 ? 416 SER B N   1 
ATOM 6401 C CA  . SER B 1 416 ? 74.785  38.896 23.187  1.00 0.47 ? 416 SER B CA  1 
ATOM 6402 C C   . SER B 1 416 ? 74.569  37.400 23.257  1.00 0.47 ? 416 SER B C   1 
ATOM 6403 O O   . SER B 1 416 ? 73.968  36.799 22.379  1.00 0.47 ? 416 SER B O   1 
ATOM 6404 C CB  . SER B 1 416 ? 74.058  39.619 24.367  1.00 0.47 ? 416 SER B CB  1 
ATOM 6405 O OG  . SER B 1 416 ? 72.717  39.187 24.609  1.00 0.47 ? 416 SER B OG  1 
ATOM 6406 N N   . THR B 1 417 ? 75.112  36.727 24.287  1.00 0.44 ? 417 THR B N   1 
ATOM 6407 C CA  . THR B 1 417 ? 75.110  35.268 24.365  1.00 0.44 ? 417 THR B CA  1 
ATOM 6408 C C   . THR B 1 417 ? 73.780  34.543 24.544  1.00 0.44 ? 417 THR B C   1 
ATOM 6409 O O   . THR B 1 417 ? 73.576  33.509 23.916  1.00 0.44 ? 417 THR B O   1 
ATOM 6410 C CB  . THR B 1 417 ? 75.996  34.762 25.494  1.00 0.44 ? 417 THR B CB  1 
ATOM 6411 O OG1 . THR B 1 417 ? 75.696  35.423 26.718  1.00 0.44 ? 417 THR B OG1 1 
ATOM 6412 C CG2 . THR B 1 417 ? 77.464  35.072 25.184  1.00 0.44 ? 417 THR B CG2 1 
ATOM 6413 N N   . GLN B 1 418 ? 72.891  35.007 25.449  1.00 0.57 ? 418 GLN B N   1 
ATOM 6414 C CA  . GLN B 1 418 ? 71.736  34.221 25.873  1.00 0.57 ? 418 GLN B CA  1 
ATOM 6415 C C   . GLN B 1 418 ? 70.396  34.954 25.889  1.00 0.57 ? 418 GLN B C   1 
ATOM 6416 O O   . GLN B 1 418 ? 69.425  34.416 26.414  1.00 0.57 ? 418 GLN B O   1 
ATOM 6417 C CB  . GLN B 1 418 ? 71.935  33.734 27.336  1.00 0.57 ? 418 GLN B CB  1 
ATOM 6418 C CG  . GLN B 1 418 ? 73.116  32.775 27.587  1.00 0.57 ? 418 GLN B CG  1 
ATOM 6419 C CD  . GLN B 1 418 ? 72.921  31.430 26.891  1.00 0.57 ? 418 GLN B CD  1 
ATOM 6420 O OE1 . GLN B 1 418 ? 71.849  31.025 26.448  1.00 0.57 ? 418 GLN B OE1 1 
ATOM 6421 N NE2 . GLN B 1 418 ? 74.029  30.655 26.827  1.00 0.57 ? 418 GLN B NE2 1 
ATOM 6422 N N   . ALA B 1 419 ? 70.309  36.185 25.365  1.00 0.70 ? 419 ALA B N   1 
ATOM 6423 C CA  . ALA B 1 419 ? 69.077  36.956 25.327  1.00 0.70 ? 419 ALA B CA  1 
ATOM 6424 C C   . ALA B 1 419 ? 67.951  36.420 24.384  1.00 0.70 ? 419 ALA B C   1 
ATOM 6425 O O   . ALA B 1 419 ? 68.180  35.383 23.702  1.00 0.70 ? 419 ALA B O   1 
ATOM 6426 C CB  . ALA B 1 419 ? 69.432  38.367 24.840  1.00 0.70 ? 419 ALA B CB  1 
ATOM 6427 O OXT . ALA B 1 419 ? 66.865  37.068 24.326  1.00 0.70 ? 419 ALA B OXT 1 
# 
