data_8ZYT
# 
_entry.id   8ZYT 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZYT         pdb_00008zyt 10.2210/pdb8zyt/pdb 
WWPDB D_1300048794 ?            ?                   
EMDB  EMD-60578    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-04-09 ? 
2  'EM metadata'     1 0 2025-04-09 ? 
3  'Half map'        1 0 2025-04-09 1 
4  'Half map'        1 0 2025-04-09 2 
5  Image             1 0 2025-04-09 ? 
6  'Primary map'     1 0 2025-04-09 ? 
7  'Structure model' 1 1 2025-04-16 ? 
8  'Half map'        1 0 2025-04-09 1 
9  'Half map'        1 0 2025-04-09 2 
10 Image             1 0 2025-04-09 ? 
11 'Primary map'     1 0 2025-04-09 ? 
12 'Structure model' 1 2 2025-05-28 ? 
13 'EM metadata'     1 1 2025-05-28 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  'Half map'        repository 'Initial release' ? ? 
4  4  'Half map'        repository 'Initial release' ? ? 
5  5  Image             repository 'Initial release' ? ? 
6  6  'Primary map'     repository 'Initial release' ? ? 
7  8  'Half map'        repository 'Initial release' ? ? 
8  9  'Half map'        repository 'Initial release' ? ? 
9  10 Image             repository 'Initial release' ? ? 
10 11 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7  'Structure model' 'Data collection'      
2 7  'Structure model' 'Database references'  
3 12 'Structure model' 'Data collection'      
4 12 'Structure model' 'Database references'  
5 12 'Structure model' 'Structure summary'    
6 13 'EM metadata'     'Database references'  
7 13 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7  'Structure model' citation              
2 7  'Structure model' citation_author       
3 7  'Structure model' em_admin              
4 12 'Structure model' em_admin              
5 12 'Structure model' pdbx_database_related 
6 12 'Structure model' struct                
7 13 'EM metadata'     em_admin              
8 13 'EM metadata'     pdbx_database_related 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  7  'Structure model' '_citation.journal_volume'          
2  7  'Structure model' '_citation.page_first'              
3  7  'Structure model' '_citation.page_last'               
4  7  'Structure model' '_citation_author.identifier_ORCID' 
5  7  'Structure model' '_em_admin.last_update'             
6  12 'Structure model' '_em_admin.last_update'             
7  12 'Structure model' '_em_admin.title'                   
8  12 'Structure model' '_pdbx_database_related.details'    
9  12 'Structure model' '_struct.title'                     
10 13 'EM metadata'     '_em_admin.last_update'             
11 13 'EM metadata'     '_em_admin.title'                   
12 13 'EM metadata'     '_pdbx_database_related.details'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZYT 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin1 and SBI-553 (complex 3)' 
_pdbx_database_related.db_id          EMD-60578 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              cltian@ustc.edu.cn 
_pdbx_contact_author.name_first         Demeng 
_pdbx_contact_author.name_last          Sun 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0045-3459 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Sun, D.'  1 ? 
'Li, X.'   2 ? 
'Yuan, Q.' 3 ? 
'Yin, W.'  4 ? 
'Xu, H.E.' 5 ? 
'Tian, C.' 6 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   CN 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Res.' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1001-0602 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            35 
_citation.language                  ? 
_citation.page_first                284 
_citation.page_last                 295 
_citation.title                     
'Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41422-025-01095-7 
_citation.pdbx_database_id_PubMed   40118988 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Sun, D.'   1  ? 
primary 'Li, X.'    2  ? 
primary 'Yuan, Q.'  3  ? 
primary 'Wang, Y.'  4  ? 
primary 'Shi, P.'   5  ? 
primary 'Zhang, H.' 6  ? 
primary 'Wang, T.'  7  ? 
primary 'Sun, W.'   8  ? 
primary 'Ling, S.'  9  ? 
primary 'Liu, Y.'   10 ? 
primary 'Lai, J.'   11 ? 
primary 'Xie, W.'   12 ? 
primary 'Yin, W.'   13 ? 
primary 'Liu, L.'   14 ? 
primary 'Xu, H.E.'  15 ? 
primary 'Tian, C.'  16 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Beta-arrestin-1 45224.598 1 ? ? ? 
'Human beta-arrestin1 was truncated at residues 382 to remove autoinhibition and added His tag at its N-terminus.' 
2 polymer     man 'Fab30 heavy chain' 27727.010 1 ? ? ? 
;The heavy chain of antibody fragment Fab30 wasmodified with a GP64 secretion signal peptide at the N-terminus, and His tag at the C-terminus.
;
3 polymer     man 'Fab30 light chain' 25436.492 1 ? ? ? 
'The heavy chain of antibody fragment Fab30 wasmodified with a GP64 secretion signal peptide at the N-terminus' 
4 polymer     man 'Soluble cytochrome b562,Neurotensin receptor type 1' 62097.848 1 ? ? ? ? 
5 polymer     syn 'neurotensin peptide 8-13' 819.007   1 ? ? ? ? 
6 non-polymer syn 
;[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
;
746.566   1 ? ? ? ? 
7 non-polymer syn '2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol' 
450.548   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Arrestin beta-1,Non-visual arrestin-2'                                                          
4 'Cytochrome b-562,NT-R-1,NTR1,High-affinity levocabastine-insensitive neurotensin receptor,NTRH' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;MGSHHHHHHHHGSLEVLFQGPGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKAC
GVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHV
TNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELD
TN
;
;MGSHHHHHHHHGSLEVLFQGPGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKAC
GVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHV
TNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELD
TN
;
B ? 
2 'polypeptide(L)' no no  
;MVSAIVLYVLLAAAAHSAFAEISEVQLVESGGGLVQPGGSLRLSCAASGFNVYSSSIHWVRQAPGKGLEWVASISSYYGY
TYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSRQFWYSGLDYWGQGTLVTVSSASTKGPSVFPLAPSSKS
TSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKK
VEPKSCDKTAAAHHHHHHHH
;
;MVSAIVLYVLLAAAAHSAFAEISEVQLVESGGGLVQPGGSLRLSCAASGFNVYSSSIHWVRQAPGKGLEWVASISSYYGY
TYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSRQFWYSGLDYWGQGTLVTVSSASTKGPSVFPLAPSSKS
TSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKK
VEPKSCDKTAAAHHHHHHHH
;
D ? 
3 'polypeptide(L)' no no  
;MVSAIVLYVLLAAAAHSAFASDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVP
SRFSGSRSGTDFTLTISSLQPEDFATYYCQQYKYVPVTFGQGTKVEIKRTVAAPSVFIFPPSDSQLKSGTASVVCLLNNF
YPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;MVSAIVLYVLLAAAAHSAFASDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVP
SRFSGSRSGTDFTLTISSLQPEDFATYYCQQYKYVPVTFGQGTKVEIKRTVAAPSVFIFPPSDSQLKSGTASVVCLLNNF
YPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
Q ? 
4 'polypeptide(L)' no yes 
;MKTIIALSYIFCLVFAGSADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFR
HGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLASGSLEVLFQGPMRLNSSAPGTPGTPAADPFQRAQA
GLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYH
LGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLALCHPFKAKTLMSRSR
TKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLT
VMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHY
FYMVTNALFYVSSTINPILYNLVSANFRHIFIATLACLCPVWRRRRKRPCFNAFSRKCD(SEP)V(SEP)(SEP)NH
(TPO)L(SEP)(SEP)NATRETLY
;
;MKTIIALSYIFCLVFAGSADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFR
HGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLASGSLEVLFQGPMRLNSSAPGTPGTPAADPFQRAQA
GLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYH
LGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLALCHPFKAKTLMSRSR
TKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLT
VMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHY
FYMVTNALFYVSSTINPILYNLVSANFRHIFIATLACLCPVWRRRRKRPCFNAFSRKCDSVSSNHTLSSNATRETLY
;
R ? 
5 'polypeptide(L)' no no  RRPYIL RRPYIL L ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
6 
;[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
;
PIO 
7 '2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol' SRW 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  HIS n 
1 12  GLY n 
1 13  SER n 
1 14  LEU n 
1 15  GLU n 
1 16  VAL n 
1 17  LEU n 
1 18  PHE n 
1 19  GLN n 
1 20  GLY n 
1 21  PRO n 
1 22  GLY n 
1 23  ASP n 
1 24  LYS n 
1 25  GLY n 
1 26  THR n 
1 27  ARG n 
1 28  VAL n 
1 29  PHE n 
1 30  LYS n 
1 31  LYS n 
1 32  ALA n 
1 33  SER n 
1 34  PRO n 
1 35  ASN n 
1 36  GLY n 
1 37  LYS n 
1 38  LEU n 
1 39  THR n 
1 40  VAL n 
1 41  TYR n 
1 42  LEU n 
1 43  GLY n 
1 44  LYS n 
1 45  ARG n 
1 46  ASP n 
1 47  PHE n 
1 48  VAL n 
1 49  ASP n 
1 50  HIS n 
1 51  ILE n 
1 52  ASP n 
1 53  LEU n 
1 54  VAL n 
1 55  ASP n 
1 56  PRO n 
1 57  VAL n 
1 58  ASP n 
1 59  GLY n 
1 60  VAL n 
1 61  VAL n 
1 62  LEU n 
1 63  VAL n 
1 64  ASP n 
1 65  PRO n 
1 66  GLU n 
1 67  TYR n 
1 68  LEU n 
1 69  LYS n 
1 70  GLU n 
1 71  ARG n 
1 72  ARG n 
1 73  VAL n 
1 74  TYR n 
1 75  VAL n 
1 76  THR n 
1 77  LEU n 
1 78  THR n 
1 79  CYS n 
1 80  ALA n 
1 81  PHE n 
1 82  ARG n 
1 83  TYR n 
1 84  GLY n 
1 85  ARG n 
1 86  GLU n 
1 87  ASP n 
1 88  LEU n 
1 89  ASP n 
1 90  VAL n 
1 91  LEU n 
1 92  GLY n 
1 93  LEU n 
1 94  THR n 
1 95  PHE n 
1 96  ARG n 
1 97  LYS n 
1 98  ASP n 
1 99  LEU n 
1 100 PHE n 
1 101 VAL n 
1 102 ALA n 
1 103 ASN n 
1 104 VAL n 
1 105 GLN n 
1 106 SER n 
1 107 PHE n 
1 108 PRO n 
1 109 PRO n 
1 110 ALA n 
1 111 PRO n 
1 112 GLU n 
1 113 ASP n 
1 114 LYS n 
1 115 LYS n 
1 116 PRO n 
1 117 LEU n 
1 118 THR n 
1 119 ARG n 
1 120 LEU n 
1 121 GLN n 
1 122 GLU n 
1 123 ARG n 
1 124 LEU n 
1 125 ILE n 
1 126 LYS n 
1 127 LYS n 
1 128 LEU n 
1 129 GLY n 
1 130 GLU n 
1 131 HIS n 
1 132 ALA n 
1 133 TYR n 
1 134 PRO n 
1 135 PHE n 
1 136 THR n 
1 137 PHE n 
1 138 GLU n 
1 139 ILE n 
1 140 PRO n 
1 141 PRO n 
1 142 ASN n 
1 143 LEU n 
1 144 PRO n 
1 145 CYS n 
1 146 SER n 
1 147 VAL n 
1 148 THR n 
1 149 LEU n 
1 150 GLN n 
1 151 PRO n 
1 152 GLY n 
1 153 PRO n 
1 154 GLU n 
1 155 ASP n 
1 156 THR n 
1 157 GLY n 
1 158 LYS n 
1 159 ALA n 
1 160 CYS n 
1 161 GLY n 
1 162 VAL n 
1 163 ASP n 
1 164 TYR n 
1 165 GLU n 
1 166 VAL n 
1 167 LYS n 
1 168 ALA n 
1 169 PHE n 
1 170 CYS n 
1 171 ALA n 
1 172 GLU n 
1 173 ASN n 
1 174 LEU n 
1 175 GLU n 
1 176 GLU n 
1 177 LYS n 
1 178 ILE n 
1 179 HIS n 
1 180 LYS n 
1 181 ARG n 
1 182 ASN n 
1 183 SER n 
1 184 VAL n 
1 185 ARG n 
1 186 LEU n 
1 187 VAL n 
1 188 ILE n 
1 189 ARG n 
1 190 LYS n 
1 191 VAL n 
1 192 GLN n 
1 193 TYR n 
1 194 ALA n 
1 195 PRO n 
1 196 GLU n 
1 197 ARG n 
1 198 PRO n 
1 199 GLY n 
1 200 PRO n 
1 201 GLN n 
1 202 PRO n 
1 203 THR n 
1 204 ALA n 
1 205 GLU n 
1 206 THR n 
1 207 THR n 
1 208 ARG n 
1 209 GLN n 
1 210 PHE n 
1 211 LEU n 
1 212 MET n 
1 213 SER n 
1 214 ASP n 
1 215 LYS n 
1 216 PRO n 
1 217 LEU n 
1 218 HIS n 
1 219 LEU n 
1 220 GLU n 
1 221 ALA n 
1 222 SER n 
1 223 LEU n 
1 224 ASP n 
1 225 LYS n 
1 226 GLU n 
1 227 ILE n 
1 228 TYR n 
1 229 TYR n 
1 230 HIS n 
1 231 GLY n 
1 232 GLU n 
1 233 PRO n 
1 234 ILE n 
1 235 SER n 
1 236 VAL n 
1 237 ASN n 
1 238 VAL n 
1 239 HIS n 
1 240 VAL n 
1 241 THR n 
1 242 ASN n 
1 243 ASN n 
1 244 THR n 
1 245 ASN n 
1 246 LYS n 
1 247 THR n 
1 248 VAL n 
1 249 LYS n 
1 250 LYS n 
1 251 ILE n 
1 252 LYS n 
1 253 ILE n 
1 254 SER n 
1 255 VAL n 
1 256 ARG n 
1 257 GLN n 
1 258 TYR n 
1 259 ALA n 
1 260 ASP n 
1 261 ILE n 
1 262 CYS n 
1 263 LEU n 
1 264 PHE n 
1 265 ASN n 
1 266 THR n 
1 267 ALA n 
1 268 GLN n 
1 269 TYR n 
1 270 LYS n 
1 271 CYS n 
1 272 PRO n 
1 273 VAL n 
1 274 ALA n 
1 275 MET n 
1 276 GLU n 
1 277 GLU n 
1 278 ALA n 
1 279 ASP n 
1 280 ASP n 
1 281 THR n 
1 282 VAL n 
1 283 ALA n 
1 284 PRO n 
1 285 SER n 
1 286 SER n 
1 287 THR n 
1 288 PHE n 
1 289 CYS n 
1 290 LYS n 
1 291 VAL n 
1 292 TYR n 
1 293 THR n 
1 294 LEU n 
1 295 THR n 
1 296 PRO n 
1 297 PHE n 
1 298 LEU n 
1 299 ALA n 
1 300 ASN n 
1 301 ASN n 
1 302 ARG n 
1 303 GLU n 
1 304 LYS n 
1 305 ARG n 
1 306 GLY n 
1 307 LEU n 
1 308 ALA n 
1 309 LEU n 
1 310 ASP n 
1 311 GLY n 
1 312 LYS n 
1 313 LEU n 
1 314 LYS n 
1 315 HIS n 
1 316 GLU n 
1 317 ASP n 
1 318 THR n 
1 319 ASN n 
1 320 LEU n 
1 321 ALA n 
1 322 SER n 
1 323 SER n 
1 324 THR n 
1 325 LEU n 
1 326 LEU n 
1 327 ARG n 
1 328 GLU n 
1 329 GLY n 
1 330 ALA n 
1 331 ASN n 
1 332 ARG n 
1 333 GLU n 
1 334 ILE n 
1 335 LEU n 
1 336 GLY n 
1 337 ILE n 
1 338 ILE n 
1 339 VAL n 
1 340 SER n 
1 341 TYR n 
1 342 LYS n 
1 343 VAL n 
1 344 LYS n 
1 345 VAL n 
1 346 LYS n 
1 347 LEU n 
1 348 VAL n 
1 349 VAL n 
1 350 SER n 
1 351 ARG n 
1 352 GLY n 
1 353 GLY n 
1 354 LEU n 
1 355 LEU n 
1 356 GLY n 
1 357 ASP n 
1 358 LEU n 
1 359 ALA n 
1 360 SER n 
1 361 SER n 
1 362 ASP n 
1 363 VAL n 
1 364 ALA n 
1 365 VAL n 
1 366 GLU n 
1 367 LEU n 
1 368 PRO n 
1 369 PHE n 
1 370 THR n 
1 371 LEU n 
1 372 MET n 
1 373 HIS n 
1 374 PRO n 
1 375 LYS n 
1 376 PRO n 
1 377 LYS n 
1 378 GLU n 
1 379 GLU n 
1 380 PRO n 
1 381 PRO n 
1 382 HIS n 
1 383 ARG n 
1 384 GLU n 
1 385 VAL n 
1 386 PRO n 
1 387 GLU n 
1 388 ASN n 
1 389 GLU n 
1 390 THR n 
1 391 PRO n 
1 392 VAL n 
1 393 ASP n 
1 394 THR n 
1 395 ASN n 
1 396 LEU n 
1 397 ILE n 
1 398 GLU n 
1 399 LEU n 
1 400 ASP n 
1 401 THR n 
1 402 ASN n 
2 1   MET n 
2 2   VAL n 
2 3   SER n 
2 4   ALA n 
2 5   ILE n 
2 6   VAL n 
2 7   LEU n 
2 8   TYR n 
2 9   VAL n 
2 10  LEU n 
2 11  LEU n 
2 12  ALA n 
2 13  ALA n 
2 14  ALA n 
2 15  ALA n 
2 16  HIS n 
2 17  SER n 
2 18  ALA n 
2 19  PHE n 
2 20  ALA n 
2 21  GLU n 
2 22  ILE n 
2 23  SER n 
2 24  GLU n 
2 25  VAL n 
2 26  GLN n 
2 27  LEU n 
2 28  VAL n 
2 29  GLU n 
2 30  SER n 
2 31  GLY n 
2 32  GLY n 
2 33  GLY n 
2 34  LEU n 
2 35  VAL n 
2 36  GLN n 
2 37  PRO n 
2 38  GLY n 
2 39  GLY n 
2 40  SER n 
2 41  LEU n 
2 42  ARG n 
2 43  LEU n 
2 44  SER n 
2 45  CYS n 
2 46  ALA n 
2 47  ALA n 
2 48  SER n 
2 49  GLY n 
2 50  PHE n 
2 51  ASN n 
2 52  VAL n 
2 53  TYR n 
2 54  SER n 
2 55  SER n 
2 56  SER n 
2 57  ILE n 
2 58  HIS n 
2 59  TRP n 
2 60  VAL n 
2 61  ARG n 
2 62  GLN n 
2 63  ALA n 
2 64  PRO n 
2 65  GLY n 
2 66  LYS n 
2 67  GLY n 
2 68  LEU n 
2 69  GLU n 
2 70  TRP n 
2 71  VAL n 
2 72  ALA n 
2 73  SER n 
2 74  ILE n 
2 75  SER n 
2 76  SER n 
2 77  TYR n 
2 78  TYR n 
2 79  GLY n 
2 80  TYR n 
2 81  THR n 
2 82  TYR n 
2 83  TYR n 
2 84  ALA n 
2 85  ASP n 
2 86  SER n 
2 87  VAL n 
2 88  LYS n 
2 89  GLY n 
2 90  ARG n 
2 91  PHE n 
2 92  THR n 
2 93  ILE n 
2 94  SER n 
2 95  ALA n 
2 96  ASP n 
2 97  THR n 
2 98  SER n 
2 99  LYS n 
2 100 ASN n 
2 101 THR n 
2 102 ALA n 
2 103 TYR n 
2 104 LEU n 
2 105 GLN n 
2 106 MET n 
2 107 ASN n 
2 108 SER n 
2 109 LEU n 
2 110 ARG n 
2 111 ALA n 
2 112 GLU n 
2 113 ASP n 
2 114 THR n 
2 115 ALA n 
2 116 VAL n 
2 117 TYR n 
2 118 TYR n 
2 119 CYS n 
2 120 ALA n 
2 121 ARG n 
2 122 SER n 
2 123 ARG n 
2 124 GLN n 
2 125 PHE n 
2 126 TRP n 
2 127 TYR n 
2 128 SER n 
2 129 GLY n 
2 130 LEU n 
2 131 ASP n 
2 132 TYR n 
2 133 TRP n 
2 134 GLY n 
2 135 GLN n 
2 136 GLY n 
2 137 THR n 
2 138 LEU n 
2 139 VAL n 
2 140 THR n 
2 141 VAL n 
2 142 SER n 
2 143 SER n 
2 144 ALA n 
2 145 SER n 
2 146 THR n 
2 147 LYS n 
2 148 GLY n 
2 149 PRO n 
2 150 SER n 
2 151 VAL n 
2 152 PHE n 
2 153 PRO n 
2 154 LEU n 
2 155 ALA n 
2 156 PRO n 
2 157 SER n 
2 158 SER n 
2 159 LYS n 
2 160 SER n 
2 161 THR n 
2 162 SER n 
2 163 GLY n 
2 164 GLY n 
2 165 THR n 
2 166 ALA n 
2 167 ALA n 
2 168 LEU n 
2 169 GLY n 
2 170 CYS n 
2 171 LEU n 
2 172 VAL n 
2 173 LYS n 
2 174 ASP n 
2 175 TYR n 
2 176 PHE n 
2 177 PRO n 
2 178 GLU n 
2 179 PRO n 
2 180 VAL n 
2 181 THR n 
2 182 VAL n 
2 183 SER n 
2 184 TRP n 
2 185 ASN n 
2 186 SER n 
2 187 GLY n 
2 188 ALA n 
2 189 LEU n 
2 190 THR n 
2 191 SER n 
2 192 GLY n 
2 193 VAL n 
2 194 HIS n 
2 195 THR n 
2 196 PHE n 
2 197 PRO n 
2 198 ALA n 
2 199 VAL n 
2 200 LEU n 
2 201 GLN n 
2 202 SER n 
2 203 SER n 
2 204 GLY n 
2 205 LEU n 
2 206 TYR n 
2 207 SER n 
2 208 LEU n 
2 209 SER n 
2 210 SER n 
2 211 VAL n 
2 212 VAL n 
2 213 THR n 
2 214 VAL n 
2 215 PRO n 
2 216 SER n 
2 217 SER n 
2 218 SER n 
2 219 LEU n 
2 220 GLY n 
2 221 THR n 
2 222 GLN n 
2 223 THR n 
2 224 TYR n 
2 225 ILE n 
2 226 CYS n 
2 227 ASN n 
2 228 VAL n 
2 229 ASN n 
2 230 HIS n 
2 231 LYS n 
2 232 PRO n 
2 233 SER n 
2 234 ASN n 
2 235 THR n 
2 236 LYS n 
2 237 VAL n 
2 238 ASP n 
2 239 LYS n 
2 240 LYS n 
2 241 VAL n 
2 242 GLU n 
2 243 PRO n 
2 244 LYS n 
2 245 SER n 
2 246 CYS n 
2 247 ASP n 
2 248 LYS n 
2 249 THR n 
2 250 ALA n 
2 251 ALA n 
2 252 ALA n 
2 253 HIS n 
2 254 HIS n 
2 255 HIS n 
2 256 HIS n 
2 257 HIS n 
2 258 HIS n 
2 259 HIS n 
2 260 HIS n 
3 1   MET n 
3 2   VAL n 
3 3   SER n 
3 4   ALA n 
3 5   ILE n 
3 6   VAL n 
3 7   LEU n 
3 8   TYR n 
3 9   VAL n 
3 10  LEU n 
3 11  LEU n 
3 12  ALA n 
3 13  ALA n 
3 14  ALA n 
3 15  ALA n 
3 16  HIS n 
3 17  SER n 
3 18  ALA n 
3 19  PHE n 
3 20  ALA n 
3 21  SER n 
3 22  ASP n 
3 23  ILE n 
3 24  GLN n 
3 25  MET n 
3 26  THR n 
3 27  GLN n 
3 28  SER n 
3 29  PRO n 
3 30  SER n 
3 31  SER n 
3 32  LEU n 
3 33  SER n 
3 34  ALA n 
3 35  SER n 
3 36  VAL n 
3 37  GLY n 
3 38  ASP n 
3 39  ARG n 
3 40  VAL n 
3 41  THR n 
3 42  ILE n 
3 43  THR n 
3 44  CYS n 
3 45  ARG n 
3 46  ALA n 
3 47  SER n 
3 48  GLN n 
3 49  SER n 
3 50  VAL n 
3 51  SER n 
3 52  SER n 
3 53  ALA n 
3 54  VAL n 
3 55  ALA n 
3 56  TRP n 
3 57  TYR n 
3 58  GLN n 
3 59  GLN n 
3 60  LYS n 
3 61  PRO n 
3 62  GLY n 
3 63  LYS n 
3 64  ALA n 
3 65  PRO n 
3 66  LYS n 
3 67  LEU n 
3 68  LEU n 
3 69  ILE n 
3 70  TYR n 
3 71  SER n 
3 72  ALA n 
3 73  SER n 
3 74  SER n 
3 75  LEU n 
3 76  TYR n 
3 77  SER n 
3 78  GLY n 
3 79  VAL n 
3 80  PRO n 
3 81  SER n 
3 82  ARG n 
3 83  PHE n 
3 84  SER n 
3 85  GLY n 
3 86  SER n 
3 87  ARG n 
3 88  SER n 
3 89  GLY n 
3 90  THR n 
3 91  ASP n 
3 92  PHE n 
3 93  THR n 
3 94  LEU n 
3 95  THR n 
3 96  ILE n 
3 97  SER n 
3 98  SER n 
3 99  LEU n 
3 100 GLN n 
3 101 PRO n 
3 102 GLU n 
3 103 ASP n 
3 104 PHE n 
3 105 ALA n 
3 106 THR n 
3 107 TYR n 
3 108 TYR n 
3 109 CYS n 
3 110 GLN n 
3 111 GLN n 
3 112 TYR n 
3 113 LYS n 
3 114 TYR n 
3 115 VAL n 
3 116 PRO n 
3 117 VAL n 
3 118 THR n 
3 119 PHE n 
3 120 GLY n 
3 121 GLN n 
3 122 GLY n 
3 123 THR n 
3 124 LYS n 
3 125 VAL n 
3 126 GLU n 
3 127 ILE n 
3 128 LYS n 
3 129 ARG n 
3 130 THR n 
3 131 VAL n 
3 132 ALA n 
3 133 ALA n 
3 134 PRO n 
3 135 SER n 
3 136 VAL n 
3 137 PHE n 
3 138 ILE n 
3 139 PHE n 
3 140 PRO n 
3 141 PRO n 
3 142 SER n 
3 143 ASP n 
3 144 SER n 
3 145 GLN n 
3 146 LEU n 
3 147 LYS n 
3 148 SER n 
3 149 GLY n 
3 150 THR n 
3 151 ALA n 
3 152 SER n 
3 153 VAL n 
3 154 VAL n 
3 155 CYS n 
3 156 LEU n 
3 157 LEU n 
3 158 ASN n 
3 159 ASN n 
3 160 PHE n 
3 161 TYR n 
3 162 PRO n 
3 163 ARG n 
3 164 GLU n 
3 165 ALA n 
3 166 LYS n 
3 167 VAL n 
3 168 GLN n 
3 169 TRP n 
3 170 LYS n 
3 171 VAL n 
3 172 ASP n 
3 173 ASN n 
3 174 ALA n 
3 175 LEU n 
3 176 GLN n 
3 177 SER n 
3 178 GLY n 
3 179 ASN n 
3 180 SER n 
3 181 GLN n 
3 182 GLU n 
3 183 SER n 
3 184 VAL n 
3 185 THR n 
3 186 GLU n 
3 187 GLN n 
3 188 ASP n 
3 189 SER n 
3 190 LYS n 
3 191 ASP n 
3 192 SER n 
3 193 THR n 
3 194 TYR n 
3 195 SER n 
3 196 LEU n 
3 197 SER n 
3 198 SER n 
3 199 THR n 
3 200 LEU n 
3 201 THR n 
3 202 LEU n 
3 203 SER n 
3 204 LYS n 
3 205 ALA n 
3 206 ASP n 
3 207 TYR n 
3 208 GLU n 
3 209 LYS n 
3 210 HIS n 
3 211 LYS n 
3 212 VAL n 
3 213 TYR n 
3 214 ALA n 
3 215 CYS n 
3 216 GLU n 
3 217 VAL n 
3 218 THR n 
3 219 HIS n 
3 220 GLN n 
3 221 GLY n 
3 222 LEU n 
3 223 SER n 
3 224 SER n 
3 225 PRO n 
3 226 VAL n 
3 227 THR n 
3 228 LYS n 
3 229 SER n 
3 230 PHE n 
3 231 ASN n 
3 232 ARG n 
3 233 GLY n 
3 234 GLU n 
3 235 CYS n 
4 1   MET n 
4 2   LYS n 
4 3   THR n 
4 4   ILE n 
4 5   ILE n 
4 6   ALA n 
4 7   LEU n 
4 8   SER n 
4 9   TYR n 
4 10  ILE n 
4 11  PHE n 
4 12  CYS n 
4 13  LEU n 
4 14  VAL n 
4 15  PHE n 
4 16  ALA n 
4 17  GLY n 
4 18  SER n 
4 19  ALA n 
4 20  ASP n 
4 21  LEU n 
4 22  GLU n 
4 23  ASP n 
4 24  ASN n 
4 25  TRP n 
4 26  GLU n 
4 27  THR n 
4 28  LEU n 
4 29  ASN n 
4 30  ASP n 
4 31  ASN n 
4 32  LEU n 
4 33  LYS n 
4 34  VAL n 
4 35  ILE n 
4 36  GLU n 
4 37  LYS n 
4 38  ALA n 
4 39  ASP n 
4 40  ASN n 
4 41  ALA n 
4 42  ALA n 
4 43  GLN n 
4 44  VAL n 
4 45  LYS n 
4 46  ASP n 
4 47  ALA n 
4 48  LEU n 
4 49  THR n 
4 50  LYS n 
4 51  MET n 
4 52  ARG n 
4 53  ALA n 
4 54  ALA n 
4 55  ALA n 
4 56  LEU n 
4 57  ASP n 
4 58  ALA n 
4 59  GLN n 
4 60  LYS n 
4 61  ALA n 
4 62  THR n 
4 63  PRO n 
4 64  PRO n 
4 65  LYS n 
4 66  LEU n 
4 67  GLU n 
4 68  ASP n 
4 69  LYS n 
4 70  SER n 
4 71  PRO n 
4 72  ASP n 
4 73  SER n 
4 74  PRO n 
4 75  GLU n 
4 76  MET n 
4 77  LYS n 
4 78  ASP n 
4 79  PHE n 
4 80  ARG n 
4 81  HIS n 
4 82  GLY n 
4 83  PHE n 
4 84  ASP n 
4 85  ILE n 
4 86  LEU n 
4 87  VAL n 
4 88  GLY n 
4 89  GLN n 
4 90  ILE n 
4 91  ASP n 
4 92  ASP n 
4 93  ALA n 
4 94  LEU n 
4 95  LYS n 
4 96  LEU n 
4 97  ALA n 
4 98  ASN n 
4 99  GLU n 
4 100 GLY n 
4 101 LYS n 
4 102 VAL n 
4 103 LYS n 
4 104 GLU n 
4 105 ALA n 
4 106 GLN n 
4 107 ALA n 
4 108 ALA n 
4 109 ALA n 
4 110 GLU n 
4 111 GLN n 
4 112 LEU n 
4 113 LYS n 
4 114 THR n 
4 115 THR n 
4 116 ARG n 
4 117 ASN n 
4 118 ALA n 
4 119 TYR n 
4 120 ILE n 
4 121 GLN n 
4 122 LYS n 
4 123 TYR n 
4 124 LEU n 
4 125 ALA n 
4 126 SER n 
4 127 GLY n 
4 128 SER n 
4 129 LEU n 
4 130 GLU n 
4 131 VAL n 
4 132 LEU n 
4 133 PHE n 
4 134 GLN n 
4 135 GLY n 
4 136 PRO n 
4 137 MET n 
4 138 ARG n 
4 139 LEU n 
4 140 ASN n 
4 141 SER n 
4 142 SER n 
4 143 ALA n 
4 144 PRO n 
4 145 GLY n 
4 146 THR n 
4 147 PRO n 
4 148 GLY n 
4 149 THR n 
4 150 PRO n 
4 151 ALA n 
4 152 ALA n 
4 153 ASP n 
4 154 PRO n 
4 155 PHE n 
4 156 GLN n 
4 157 ARG n 
4 158 ALA n 
4 159 GLN n 
4 160 ALA n 
4 161 GLY n 
4 162 LEU n 
4 163 GLU n 
4 164 GLU n 
4 165 ALA n 
4 166 LEU n 
4 167 LEU n 
4 168 ALA n 
4 169 PRO n 
4 170 GLY n 
4 171 PHE n 
4 172 GLY n 
4 173 ASN n 
4 174 ALA n 
4 175 SER n 
4 176 GLY n 
4 177 ASN n 
4 178 ALA n 
4 179 SER n 
4 180 GLU n 
4 181 ARG n 
4 182 VAL n 
4 183 LEU n 
4 184 ALA n 
4 185 ALA n 
4 186 PRO n 
4 187 SER n 
4 188 SER n 
4 189 GLU n 
4 190 LEU n 
4 191 ASP n 
4 192 VAL n 
4 193 ASN n 
4 194 THR n 
4 195 ASP n 
4 196 ILE n 
4 197 TYR n 
4 198 SER n 
4 199 LYS n 
4 200 VAL n 
4 201 LEU n 
4 202 VAL n 
4 203 THR n 
4 204 ALA n 
4 205 VAL n 
4 206 TYR n 
4 207 LEU n 
4 208 ALA n 
4 209 LEU n 
4 210 PHE n 
4 211 VAL n 
4 212 VAL n 
4 213 GLY n 
4 214 THR n 
4 215 VAL n 
4 216 GLY n 
4 217 ASN n 
4 218 THR n 
4 219 VAL n 
4 220 THR n 
4 221 ALA n 
4 222 PHE n 
4 223 THR n 
4 224 LEU n 
4 225 ALA n 
4 226 ARG n 
4 227 LYS n 
4 228 LYS n 
4 229 SER n 
4 230 LEU n 
4 231 GLN n 
4 232 SER n 
4 233 LEU n 
4 234 GLN n 
4 235 SER n 
4 236 THR n 
4 237 VAL n 
4 238 HIS n 
4 239 TYR n 
4 240 HIS n 
4 241 LEU n 
4 242 GLY n 
4 243 SER n 
4 244 LEU n 
4 245 ALA n 
4 246 LEU n 
4 247 SER n 
4 248 ASP n 
4 249 LEU n 
4 250 LEU n 
4 251 THR n 
4 252 LEU n 
4 253 LEU n 
4 254 LEU n 
4 255 ALA n 
4 256 MET n 
4 257 PRO n 
4 258 VAL n 
4 259 GLU n 
4 260 LEU n 
4 261 TYR n 
4 262 ASN n 
4 263 PHE n 
4 264 ILE n 
4 265 TRP n 
4 266 VAL n 
4 267 HIS n 
4 268 HIS n 
4 269 PRO n 
4 270 TRP n 
4 271 ALA n 
4 272 PHE n 
4 273 GLY n 
4 274 ASP n 
4 275 ALA n 
4 276 GLY n 
4 277 CYS n 
4 278 ARG n 
4 279 GLY n 
4 280 TYR n 
4 281 TYR n 
4 282 PHE n 
4 283 LEU n 
4 284 ARG n 
4 285 ASP n 
4 286 ALA n 
4 287 CYS n 
4 288 THR n 
4 289 TYR n 
4 290 ALA n 
4 291 THR n 
4 292 ALA n 
4 293 LEU n 
4 294 ASN n 
4 295 VAL n 
4 296 ALA n 
4 297 SER n 
4 298 LEU n 
4 299 SER n 
4 300 VAL n 
4 301 GLU n 
4 302 ARG n 
4 303 TYR n 
4 304 LEU n 
4 305 ALA n 
4 306 LEU n 
4 307 CYS n 
4 308 HIS n 
4 309 PRO n 
4 310 PHE n 
4 311 LYS n 
4 312 ALA n 
4 313 LYS n 
4 314 THR n 
4 315 LEU n 
4 316 MET n 
4 317 SER n 
4 318 ARG n 
4 319 SER n 
4 320 ARG n 
4 321 THR n 
4 322 LYS n 
4 323 LYS n 
4 324 PHE n 
4 325 ILE n 
4 326 SER n 
4 327 ALA n 
4 328 ILE n 
4 329 TRP n 
4 330 LEU n 
4 331 ALA n 
4 332 SER n 
4 333 ALA n 
4 334 LEU n 
4 335 LEU n 
4 336 ALA n 
4 337 VAL n 
4 338 PRO n 
4 339 MET n 
4 340 LEU n 
4 341 PHE n 
4 342 THR n 
4 343 MET n 
4 344 GLY n 
4 345 GLU n 
4 346 GLN n 
4 347 ASN n 
4 348 ARG n 
4 349 SER n 
4 350 ALA n 
4 351 ASP n 
4 352 GLY n 
4 353 GLN n 
4 354 HIS n 
4 355 ALA n 
4 356 GLY n 
4 357 GLY n 
4 358 LEU n 
4 359 VAL n 
4 360 CYS n 
4 361 THR n 
4 362 PRO n 
4 363 THR n 
4 364 ILE n 
4 365 HIS n 
4 366 THR n 
4 367 ALA n 
4 368 THR n 
4 369 VAL n 
4 370 LYS n 
4 371 VAL n 
4 372 VAL n 
4 373 ILE n 
4 374 GLN n 
4 375 VAL n 
4 376 ASN n 
4 377 THR n 
4 378 PHE n 
4 379 MET n 
4 380 SER n 
4 381 PHE n 
4 382 ILE n 
4 383 PHE n 
4 384 PRO n 
4 385 MET n 
4 386 VAL n 
4 387 VAL n 
4 388 ILE n 
4 389 SER n 
4 390 VAL n 
4 391 LEU n 
4 392 ASN n 
4 393 THR n 
4 394 ILE n 
4 395 ILE n 
4 396 ALA n 
4 397 ASN n 
4 398 LYS n 
4 399 LEU n 
4 400 THR n 
4 401 VAL n 
4 402 MET n 
4 403 VAL n 
4 404 ARG n 
4 405 GLN n 
4 406 ALA n 
4 407 ALA n 
4 408 GLU n 
4 409 GLN n 
4 410 GLY n 
4 411 GLN n 
4 412 VAL n 
4 413 CYS n 
4 414 THR n 
4 415 VAL n 
4 416 GLY n 
4 417 GLY n 
4 418 GLU n 
4 419 HIS n 
4 420 SER n 
4 421 THR n 
4 422 PHE n 
4 423 SER n 
4 424 MET n 
4 425 ALA n 
4 426 ILE n 
4 427 GLU n 
4 428 PRO n 
4 429 GLY n 
4 430 ARG n 
4 431 VAL n 
4 432 GLN n 
4 433 ALA n 
4 434 LEU n 
4 435 ARG n 
4 436 HIS n 
4 437 GLY n 
4 438 VAL n 
4 439 ARG n 
4 440 VAL n 
4 441 LEU n 
4 442 ARG n 
4 443 ALA n 
4 444 VAL n 
4 445 VAL n 
4 446 ILE n 
4 447 ALA n 
4 448 PHE n 
4 449 VAL n 
4 450 VAL n 
4 451 CYS n 
4 452 TRP n 
4 453 LEU n 
4 454 PRO n 
4 455 TYR n 
4 456 HIS n 
4 457 VAL n 
4 458 ARG n 
4 459 ARG n 
4 460 LEU n 
4 461 MET n 
4 462 PHE n 
4 463 CYS n 
4 464 TYR n 
4 465 ILE n 
4 466 SER n 
4 467 ASP n 
4 468 GLU n 
4 469 GLN n 
4 470 TRP n 
4 471 THR n 
4 472 PRO n 
4 473 PHE n 
4 474 LEU n 
4 475 TYR n 
4 476 ASP n 
4 477 PHE n 
4 478 TYR n 
4 479 HIS n 
4 480 TYR n 
4 481 PHE n 
4 482 TYR n 
4 483 MET n 
4 484 VAL n 
4 485 THR n 
4 486 ASN n 
4 487 ALA n 
4 488 LEU n 
4 489 PHE n 
4 490 TYR n 
4 491 VAL n 
4 492 SER n 
4 493 SER n 
4 494 THR n 
4 495 ILE n 
4 496 ASN n 
4 497 PRO n 
4 498 ILE n 
4 499 LEU n 
4 500 TYR n 
4 501 ASN n 
4 502 LEU n 
4 503 VAL n 
4 504 SER n 
4 505 ALA n 
4 506 ASN n 
4 507 PHE n 
4 508 ARG n 
4 509 HIS n 
4 510 ILE n 
4 511 PHE n 
4 512 ILE n 
4 513 ALA n 
4 514 THR n 
4 515 LEU n 
4 516 ALA n 
4 517 CYS n 
4 518 LEU n 
4 519 CYS n 
4 520 PRO n 
4 521 VAL n 
4 522 TRP n 
4 523 ARG n 
4 524 ARG n 
4 525 ARG n 
4 526 ARG n 
4 527 LYS n 
4 528 ARG n 
4 529 PRO n 
4 530 CYS n 
4 531 PHE n 
4 532 ASN n 
4 533 ALA n 
4 534 PHE n 
4 535 SER n 
4 536 ARG n 
4 537 LYS n 
4 538 CYS n 
4 539 ASP n 
4 540 SEP n 
4 541 VAL n 
4 542 SEP n 
4 543 SEP n 
4 544 ASN n 
4 545 HIS n 
4 546 TPO n 
4 547 LEU n 
4 548 SEP n 
4 549 SEP n 
4 550 ASN n 
4 551 ALA n 
4 552 THR n 
4 553 ARG n 
4 554 GLU n 
4 555 THR n 
4 556 LEU n 
4 557 TYR n 
5 1   ARG n 
5 2   ARG n 
5 3   PRO n 
5 4   TYR n 
5 5   ILE n 
5 6   LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   402 human ? 'ARRB1, ARR1' ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21'                         511693  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? pET28a ? ? 
2 1 sample 'Biological sequence' 1   260 human ? ?             ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda'                         7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?      ? ? 
3 1 sample 'Biological sequence' 1   235 human ? ?             ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda'                         7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?      ? ? 
4 1 sample 'Biological sequence' 1   136 ?     ? cybC          ? ? ? ? ? ? 'Escherichia coli' 562  ? ? ? ? ? ? ? ? 
'Mammalian expression vector Flag-MCS-pcDNA3.1' 2021188 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?      ? ? 
4 2 sample 'Biological sequence' 137 557 human ? 'NTSR1, NTRR' ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Mammalian expression vector Flag-MCS-pcDNA3.1' 2021188 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?      ? ? 
# 
_pdbx_entity_src_syn.entity_id              5 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       6 
_pdbx_entity_src_syn.organism_scientific    'Homo sapiens' 
_pdbx_entity_src_syn.organism_common_name   human 
_pdbx_entity_src_syn.ncbi_taxonomy_id       9606 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ?                                                                'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE ?                                                                'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                                                                'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                                                'C4 H7 N O4'      
133.103 
CYS 'L-peptide linking' y CYSTEINE ?                                                                'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                                                                'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                                                'C5 H9 N O4'      
147.129 
GLY 'peptide linking'   y GLYCINE ?                                                                'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE ?                                                                'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE ?                                                                'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE ?                                                                'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE ?                                                                'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE ?                                                                'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                                                                'C9 H11 N O2'     165.189 
PIO non-polymer         . 
;[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
;
'dioctanoyl l-alpha-phosphatidyl-d-myo-inositol 4,5-diphosphate' 'C25 H49 O19 P3'  746.566 
PRO 'L-peptide linking' y PROLINE ?                                                                'C5 H9 N O2'      115.130 
SEP 'L-peptide linking' n PHOSPHOSERINE PHOSPHONOSERINE                                                  'C3 H8 N O6 P'    185.072 
SER 'L-peptide linking' y SERINE ?                                                                'C3 H7 N O3'      105.093 
SRW non-polymer         . 
'2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol' ? 'C26 H31 F N4 O2' 
450.548 
THR 'L-peptide linking' y THREONINE ?                                                                'C4 H9 N O3'      119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE PHOSPHONOTHREONINE                                               'C4 H10 N O6 P'   
199.099 
TRP 'L-peptide linking' y TRYPTOPHAN ?                                                                'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE ?                                                                'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE ?                                                                'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -20  ?   ?   ?   B . n 
A 1 2   GLY 2   -19  ?   ?   ?   B . n 
A 1 3   SER 3   -18  ?   ?   ?   B . n 
A 1 4   HIS 4   -17  ?   ?   ?   B . n 
A 1 5   HIS 5   -16  ?   ?   ?   B . n 
A 1 6   HIS 6   -15  ?   ?   ?   B . n 
A 1 7   HIS 7   -14  ?   ?   ?   B . n 
A 1 8   HIS 8   -13  ?   ?   ?   B . n 
A 1 9   HIS 9   -12  ?   ?   ?   B . n 
A 1 10  HIS 10  -11  ?   ?   ?   B . n 
A 1 11  HIS 11  -10  ?   ?   ?   B . n 
A 1 12  GLY 12  -9   ?   ?   ?   B . n 
A 1 13  SER 13  -8   ?   ?   ?   B . n 
A 1 14  LEU 14  -7   ?   ?   ?   B . n 
A 1 15  GLU 15  -6   ?   ?   ?   B . n 
A 1 16  VAL 16  -5   ?   ?   ?   B . n 
A 1 17  LEU 17  -4   ?   ?   ?   B . n 
A 1 18  PHE 18  -3   ?   ?   ?   B . n 
A 1 19  GLN 19  -2   ?   ?   ?   B . n 
A 1 20  GLY 20  -1   ?   ?   ?   B . n 
A 1 21  PRO 21  0    ?   ?   ?   B . n 
A 1 22  GLY 22  1    ?   ?   ?   B . n 
A 1 23  ASP 23  2    ?   ?   ?   B . n 
A 1 24  LYS 24  3    ?   ?   ?   B . n 
A 1 25  GLY 25  4    ?   ?   ?   B . n 
A 1 26  THR 26  5    5   THR THR B . n 
A 1 27  ARG 27  6    6   ARG ARG B . n 
A 1 28  VAL 28  7    7   VAL VAL B . n 
A 1 29  PHE 29  8    8   PHE PHE B . n 
A 1 30  LYS 30  9    9   LYS LYS B . n 
A 1 31  LYS 31  10   10  LYS LYS B . n 
A 1 32  ALA 32  11   11  ALA ALA B . n 
A 1 33  SER 33  12   12  SER SER B . n 
A 1 34  PRO 34  13   13  PRO PRO B . n 
A 1 35  ASN 35  14   14  ASN ASN B . n 
A 1 36  GLY 36  15   15  GLY GLY B . n 
A 1 37  LYS 37  16   16  LYS LYS B . n 
A 1 38  LEU 38  17   17  LEU LEU B . n 
A 1 39  THR 39  18   18  THR THR B . n 
A 1 40  VAL 40  19   19  VAL VAL B . n 
A 1 41  TYR 41  20   20  TYR TYR B . n 
A 1 42  LEU 42  21   21  LEU LEU B . n 
A 1 43  GLY 43  22   22  GLY GLY B . n 
A 1 44  LYS 44  23   23  LYS LYS B . n 
A 1 45  ARG 45  24   24  ARG ARG B . n 
A 1 46  ASP 46  25   25  ASP ASP B . n 
A 1 47  PHE 47  26   26  PHE PHE B . n 
A 1 48  VAL 48  27   27  VAL VAL B . n 
A 1 49  ASP 49  28   28  ASP ASP B . n 
A 1 50  HIS 50  29   29  HIS HIS B . n 
A 1 51  ILE 51  30   30  ILE ILE B . n 
A 1 52  ASP 52  31   31  ASP ASP B . n 
A 1 53  LEU 53  32   32  LEU LEU B . n 
A 1 54  VAL 54  33   33  VAL VAL B . n 
A 1 55  ASP 55  34   34  ASP ASP B . n 
A 1 56  PRO 56  35   35  PRO PRO B . n 
A 1 57  VAL 57  36   36  VAL VAL B . n 
A 1 58  ASP 58  37   37  ASP ASP B . n 
A 1 59  GLY 59  38   38  GLY GLY B . n 
A 1 60  VAL 60  39   39  VAL VAL B . n 
A 1 61  VAL 61  40   40  VAL VAL B . n 
A 1 62  LEU 62  41   41  LEU LEU B . n 
A 1 63  VAL 63  42   42  VAL VAL B . n 
A 1 64  ASP 64  43   43  ASP ASP B . n 
A 1 65  PRO 65  44   44  PRO PRO B . n 
A 1 66  GLU 66  45   45  GLU GLU B . n 
A 1 67  TYR 67  46   46  TYR TYR B . n 
A 1 68  LEU 68  47   47  LEU LEU B . n 
A 1 69  LYS 69  48   48  LYS LYS B . n 
A 1 70  GLU 70  49   49  GLU GLU B . n 
A 1 71  ARG 71  50   50  ARG ARG B . n 
A 1 72  ARG 72  51   51  ARG ARG B . n 
A 1 73  VAL 73  52   52  VAL VAL B . n 
A 1 74  TYR 74  53   53  TYR TYR B . n 
A 1 75  VAL 75  54   54  VAL VAL B . n 
A 1 76  THR 76  55   55  THR THR B . n 
A 1 77  LEU 77  56   56  LEU LEU B . n 
A 1 78  THR 78  57   57  THR THR B . n 
A 1 79  CYS 79  58   58  CYS CYS B . n 
A 1 80  ALA 80  59   59  ALA ALA B . n 
A 1 81  PHE 81  60   60  PHE PHE B . n 
A 1 82  ARG 82  61   61  ARG ARG B . n 
A 1 83  TYR 83  62   62  TYR TYR B . n 
A 1 84  GLY 84  63   63  GLY GLY B . n 
A 1 85  ARG 85  64   64  ARG ARG B . n 
A 1 86  GLU 86  65   65  GLU GLU B . n 
A 1 87  ASP 87  66   66  ASP ASP B . n 
A 1 88  LEU 88  67   67  LEU LEU B . n 
A 1 89  ASP 89  68   68  ASP ASP B . n 
A 1 90  VAL 90  69   69  VAL VAL B . n 
A 1 91  LEU 91  70   70  LEU LEU B . n 
A 1 92  GLY 92  71   71  GLY GLY B . n 
A 1 93  LEU 93  72   72  LEU LEU B . n 
A 1 94  THR 94  73   73  THR THR B . n 
A 1 95  PHE 95  74   74  PHE PHE B . n 
A 1 96  ARG 96  75   75  ARG ARG B . n 
A 1 97  LYS 97  76   76  LYS LYS B . n 
A 1 98  ASP 98  77   77  ASP ASP B . n 
A 1 99  LEU 99  78   78  LEU LEU B . n 
A 1 100 PHE 100 79   79  PHE PHE B . n 
A 1 101 VAL 101 80   80  VAL VAL B . n 
A 1 102 ALA 102 81   81  ALA ALA B . n 
A 1 103 ASN 103 82   82  ASN ASN B . n 
A 1 104 VAL 104 83   83  VAL VAL B . n 
A 1 105 GLN 105 84   84  GLN GLN B . n 
A 1 106 SER 106 85   85  SER SER B . n 
A 1 107 PHE 107 86   86  PHE PHE B . n 
A 1 108 PRO 108 87   87  PRO PRO B . n 
A 1 109 PRO 109 88   88  PRO PRO B . n 
A 1 110 ALA 110 89   89  ALA ALA B . n 
A 1 111 PRO 111 90   90  PRO PRO B . n 
A 1 112 GLU 112 91   91  GLU GLU B . n 
A 1 113 ASP 113 92   92  ASP ASP B . n 
A 1 114 LYS 114 93   93  LYS LYS B . n 
A 1 115 LYS 115 94   94  LYS LYS B . n 
A 1 116 PRO 116 95   95  PRO PRO B . n 
A 1 117 LEU 117 96   96  LEU LEU B . n 
A 1 118 THR 118 97   97  THR THR B . n 
A 1 119 ARG 119 98   98  ARG ARG B . n 
A 1 120 LEU 120 99   99  LEU LEU B . n 
A 1 121 GLN 121 100  100 GLN GLN B . n 
A 1 122 GLU 122 101  101 GLU GLU B . n 
A 1 123 ARG 123 102  102 ARG ARG B . n 
A 1 124 LEU 124 103  103 LEU LEU B . n 
A 1 125 ILE 125 104  104 ILE ILE B . n 
A 1 126 LYS 126 105  105 LYS LYS B . n 
A 1 127 LYS 127 106  106 LYS LYS B . n 
A 1 128 LEU 128 107  107 LEU LEU B . n 
A 1 129 GLY 129 108  108 GLY GLY B . n 
A 1 130 GLU 130 109  109 GLU GLU B . n 
A 1 131 HIS 131 110  110 HIS HIS B . n 
A 1 132 ALA 132 111  111 ALA ALA B . n 
A 1 133 TYR 133 112  112 TYR TYR B . n 
A 1 134 PRO 134 113  113 PRO PRO B . n 
A 1 135 PHE 135 114  114 PHE PHE B . n 
A 1 136 THR 136 115  115 THR THR B . n 
A 1 137 PHE 137 116  116 PHE PHE B . n 
A 1 138 GLU 138 117  117 GLU GLU B . n 
A 1 139 ILE 139 118  118 ILE ILE B . n 
A 1 140 PRO 140 119  119 PRO PRO B . n 
A 1 141 PRO 141 120  120 PRO PRO B . n 
A 1 142 ASN 142 121  121 ASN ASN B . n 
A 1 143 LEU 143 122  122 LEU LEU B . n 
A 1 144 PRO 144 123  123 PRO PRO B . n 
A 1 145 CYS 145 124  124 CYS CYS B . n 
A 1 146 SER 146 125  125 SER SER B . n 
A 1 147 VAL 147 126  126 VAL VAL B . n 
A 1 148 THR 148 127  127 THR THR B . n 
A 1 149 LEU 149 128  128 LEU LEU B . n 
A 1 150 GLN 150 129  129 GLN GLN B . n 
A 1 151 PRO 151 130  130 PRO PRO B . n 
A 1 152 GLY 152 131  131 GLY GLY B . n 
A 1 153 PRO 153 132  132 PRO PRO B . n 
A 1 154 GLU 154 133  133 GLU GLU B . n 
A 1 155 ASP 155 134  134 ASP ASP B . n 
A 1 156 THR 156 135  135 THR THR B . n 
A 1 157 GLY 157 136  136 GLY GLY B . n 
A 1 158 LYS 158 137  137 LYS LYS B . n 
A 1 159 ALA 159 138  138 ALA ALA B . n 
A 1 160 CYS 160 139  139 CYS CYS B . n 
A 1 161 GLY 161 140  140 GLY GLY B . n 
A 1 162 VAL 162 141  141 VAL VAL B . n 
A 1 163 ASP 163 142  142 ASP ASP B . n 
A 1 164 TYR 164 143  143 TYR TYR B . n 
A 1 165 GLU 165 144  144 GLU GLU B . n 
A 1 166 VAL 166 145  145 VAL VAL B . n 
A 1 167 LYS 167 146  146 LYS LYS B . n 
A 1 168 ALA 168 147  147 ALA ALA B . n 
A 1 169 PHE 169 148  148 PHE PHE B . n 
A 1 170 CYS 170 149  149 CYS CYS B . n 
A 1 171 ALA 171 150  150 ALA ALA B . n 
A 1 172 GLU 172 151  151 GLU GLU B . n 
A 1 173 ASN 173 152  152 ASN ASN B . n 
A 1 174 LEU 174 153  153 LEU LEU B . n 
A 1 175 GLU 175 154  154 GLU GLU B . n 
A 1 176 GLU 176 155  155 GLU GLU B . n 
A 1 177 LYS 177 156  156 LYS LYS B . n 
A 1 178 ILE 178 157  157 ILE ILE B . n 
A 1 179 HIS 179 158  158 HIS HIS B . n 
A 1 180 LYS 180 159  159 LYS LYS B . n 
A 1 181 ARG 181 160  160 ARG ARG B . n 
A 1 182 ASN 182 161  161 ASN ASN B . n 
A 1 183 SER 183 162  162 SER SER B . n 
A 1 184 VAL 184 163  163 VAL VAL B . n 
A 1 185 ARG 185 164  164 ARG ARG B . n 
A 1 186 LEU 186 165  165 LEU LEU B . n 
A 1 187 VAL 187 166  166 VAL VAL B . n 
A 1 188 ILE 188 167  167 ILE ILE B . n 
A 1 189 ARG 189 168  168 ARG ARG B . n 
A 1 190 LYS 190 169  169 LYS LYS B . n 
A 1 191 VAL 191 170  170 VAL VAL B . n 
A 1 192 GLN 192 171  171 GLN GLN B . n 
A 1 193 TYR 193 172  172 TYR TYR B . n 
A 1 194 ALA 194 173  173 ALA ALA B . n 
A 1 195 PRO 195 174  174 PRO PRO B . n 
A 1 196 GLU 196 175  175 GLU GLU B . n 
A 1 197 ARG 197 176  176 ARG ARG B . n 
A 1 198 PRO 198 177  177 PRO PRO B . n 
A 1 199 GLY 199 178  178 GLY GLY B . n 
A 1 200 PRO 200 179  179 PRO PRO B . n 
A 1 201 GLN 201 180  180 GLN GLN B . n 
A 1 202 PRO 202 181  181 PRO PRO B . n 
A 1 203 THR 203 182  182 THR THR B . n 
A 1 204 ALA 204 183  183 ALA ALA B . n 
A 1 205 GLU 205 184  184 GLU GLU B . n 
A 1 206 THR 206 185  185 THR THR B . n 
A 1 207 THR 207 186  186 THR THR B . n 
A 1 208 ARG 208 187  187 ARG ARG B . n 
A 1 209 GLN 209 188  188 GLN GLN B . n 
A 1 210 PHE 210 189  189 PHE PHE B . n 
A 1 211 LEU 211 190  190 LEU LEU B . n 
A 1 212 MET 212 191  191 MET MET B . n 
A 1 213 SER 213 192  192 SER SER B . n 
A 1 214 ASP 214 193  193 ASP ASP B . n 
A 1 215 LYS 215 194  194 LYS LYS B . n 
A 1 216 PRO 216 195  195 PRO PRO B . n 
A 1 217 LEU 217 196  196 LEU LEU B . n 
A 1 218 HIS 218 197  197 HIS HIS B . n 
A 1 219 LEU 219 198  198 LEU LEU B . n 
A 1 220 GLU 220 199  199 GLU GLU B . n 
A 1 221 ALA 221 200  200 ALA ALA B . n 
A 1 222 SER 222 201  201 SER SER B . n 
A 1 223 LEU 223 202  202 LEU LEU B . n 
A 1 224 ASP 224 203  203 ASP ASP B . n 
A 1 225 LYS 225 204  204 LYS LYS B . n 
A 1 226 GLU 226 205  205 GLU GLU B . n 
A 1 227 ILE 227 206  206 ILE ILE B . n 
A 1 228 TYR 228 207  207 TYR TYR B . n 
A 1 229 TYR 229 208  208 TYR TYR B . n 
A 1 230 HIS 230 209  209 HIS HIS B . n 
A 1 231 GLY 231 210  210 GLY GLY B . n 
A 1 232 GLU 232 211  211 GLU GLU B . n 
A 1 233 PRO 233 212  212 PRO PRO B . n 
A 1 234 ILE 234 213  213 ILE ILE B . n 
A 1 235 SER 235 214  214 SER SER B . n 
A 1 236 VAL 236 215  215 VAL VAL B . n 
A 1 237 ASN 237 216  216 ASN ASN B . n 
A 1 238 VAL 238 217  217 VAL VAL B . n 
A 1 239 HIS 239 218  218 HIS HIS B . n 
A 1 240 VAL 240 219  219 VAL VAL B . n 
A 1 241 THR 241 220  220 THR THR B . n 
A 1 242 ASN 242 221  221 ASN ASN B . n 
A 1 243 ASN 243 222  222 ASN ASN B . n 
A 1 244 THR 244 223  223 THR THR B . n 
A 1 245 ASN 245 224  224 ASN ASN B . n 
A 1 246 LYS 246 225  225 LYS LYS B . n 
A 1 247 THR 247 226  226 THR THR B . n 
A 1 248 VAL 248 227  227 VAL VAL B . n 
A 1 249 LYS 249 228  228 LYS LYS B . n 
A 1 250 LYS 250 229  229 LYS LYS B . n 
A 1 251 ILE 251 230  230 ILE ILE B . n 
A 1 252 LYS 252 231  231 LYS LYS B . n 
A 1 253 ILE 253 232  232 ILE ILE B . n 
A 1 254 SER 254 233  233 SER SER B . n 
A 1 255 VAL 255 234  234 VAL VAL B . n 
A 1 256 ARG 256 235  235 ARG ARG B . n 
A 1 257 GLN 257 236  236 GLN GLN B . n 
A 1 258 TYR 258 237  237 TYR TYR B . n 
A 1 259 ALA 259 238  238 ALA ALA B . n 
A 1 260 ASP 260 239  239 ASP ASP B . n 
A 1 261 ILE 261 240  240 ILE ILE B . n 
A 1 262 CYS 262 241  241 CYS CYS B . n 
A 1 263 LEU 263 242  242 LEU LEU B . n 
A 1 264 PHE 264 243  243 PHE PHE B . n 
A 1 265 ASN 265 244  244 ASN ASN B . n 
A 1 266 THR 266 245  245 THR THR B . n 
A 1 267 ALA 267 246  246 ALA ALA B . n 
A 1 268 GLN 268 247  247 GLN GLN B . n 
A 1 269 TYR 269 248  248 TYR TYR B . n 
A 1 270 LYS 270 249  249 LYS LYS B . n 
A 1 271 CYS 271 250  250 CYS CYS B . n 
A 1 272 PRO 272 251  251 PRO PRO B . n 
A 1 273 VAL 273 252  252 VAL VAL B . n 
A 1 274 ALA 274 253  253 ALA ALA B . n 
A 1 275 MET 275 254  254 MET MET B . n 
A 1 276 GLU 276 255  255 GLU GLU B . n 
A 1 277 GLU 277 256  256 GLU GLU B . n 
A 1 278 ALA 278 257  257 ALA ALA B . n 
A 1 279 ASP 279 258  258 ASP ASP B . n 
A 1 280 ASP 280 259  259 ASP ASP B . n 
A 1 281 THR 281 260  260 THR THR B . n 
A 1 282 VAL 282 261  261 VAL VAL B . n 
A 1 283 ALA 283 262  262 ALA ALA B . n 
A 1 284 PRO 284 263  263 PRO PRO B . n 
A 1 285 SER 285 264  264 SER SER B . n 
A 1 286 SER 286 265  265 SER SER B . n 
A 1 287 THR 287 266  266 THR THR B . n 
A 1 288 PHE 288 267  267 PHE PHE B . n 
A 1 289 CYS 289 268  268 CYS CYS B . n 
A 1 290 LYS 290 269  269 LYS LYS B . n 
A 1 291 VAL 291 270  270 VAL VAL B . n 
A 1 292 TYR 292 271  271 TYR TYR B . n 
A 1 293 THR 293 272  272 THR THR B . n 
A 1 294 LEU 294 273  273 LEU LEU B . n 
A 1 295 THR 295 274  274 THR THR B . n 
A 1 296 PRO 296 275  275 PRO PRO B . n 
A 1 297 PHE 297 276  276 PHE PHE B . n 
A 1 298 LEU 298 277  277 LEU LEU B . n 
A 1 299 ALA 299 278  278 ALA ALA B . n 
A 1 300 ASN 300 279  279 ASN ASN B . n 
A 1 301 ASN 301 280  280 ASN ASN B . n 
A 1 302 ARG 302 281  281 ARG ARG B . n 
A 1 303 GLU 303 282  282 GLU GLU B . n 
A 1 304 LYS 304 283  283 LYS LYS B . n 
A 1 305 ARG 305 284  284 ARG ARG B . n 
A 1 306 GLY 306 285  285 GLY GLY B . n 
A 1 307 LEU 307 286  286 LEU LEU B . n 
A 1 308 ALA 308 287  287 ALA ALA B . n 
A 1 309 LEU 309 288  288 LEU LEU B . n 
A 1 310 ASP 310 289  289 ASP ASP B . n 
A 1 311 GLY 311 290  290 GLY GLY B . n 
A 1 312 LYS 312 291  291 LYS LYS B . n 
A 1 313 LEU 313 292  292 LEU LEU B . n 
A 1 314 LYS 314 293  293 LYS LYS B . n 
A 1 315 HIS 315 294  294 HIS HIS B . n 
A 1 316 GLU 316 295  295 GLU GLU B . n 
A 1 317 ASP 317 296  296 ASP ASP B . n 
A 1 318 THR 318 297  297 THR THR B . n 
A 1 319 ASN 319 298  298 ASN ASN B . n 
A 1 320 LEU 320 299  299 LEU LEU B . n 
A 1 321 ALA 321 300  300 ALA ALA B . n 
A 1 322 SER 322 301  301 SER SER B . n 
A 1 323 SER 323 302  302 SER SER B . n 
A 1 324 THR 324 303  303 THR THR B . n 
A 1 325 LEU 325 304  304 LEU LEU B . n 
A 1 326 LEU 326 305  305 LEU LEU B . n 
A 1 327 ARG 327 306  306 ARG ARG B . n 
A 1 328 GLU 328 307  307 GLU GLU B . n 
A 1 329 GLY 329 308  308 GLY GLY B . n 
A 1 330 ALA 330 309  309 ALA ALA B . n 
A 1 331 ASN 331 310  310 ASN ASN B . n 
A 1 332 ARG 332 311  311 ARG ARG B . n 
A 1 333 GLU 333 312  312 GLU GLU B . n 
A 1 334 ILE 334 313  313 ILE ILE B . n 
A 1 335 LEU 335 314  314 LEU LEU B . n 
A 1 336 GLY 336 315  315 GLY GLY B . n 
A 1 337 ILE 337 316  316 ILE ILE B . n 
A 1 338 ILE 338 317  317 ILE ILE B . n 
A 1 339 VAL 339 318  318 VAL VAL B . n 
A 1 340 SER 340 319  319 SER SER B . n 
A 1 341 TYR 341 320  320 TYR TYR B . n 
A 1 342 LYS 342 321  321 LYS LYS B . n 
A 1 343 VAL 343 322  322 VAL VAL B . n 
A 1 344 LYS 344 323  323 LYS LYS B . n 
A 1 345 VAL 345 324  324 VAL VAL B . n 
A 1 346 LYS 346 325  325 LYS LYS B . n 
A 1 347 LEU 347 326  326 LEU LEU B . n 
A 1 348 VAL 348 327  327 VAL VAL B . n 
A 1 349 VAL 349 328  328 VAL VAL B . n 
A 1 350 SER 350 329  329 SER SER B . n 
A 1 351 ARG 351 330  330 ARG ARG B . n 
A 1 352 GLY 352 331  331 GLY GLY B . n 
A 1 353 GLY 353 332  332 GLY GLY B . n 
A 1 354 LEU 354 333  333 LEU LEU B . n 
A 1 355 LEU 355 334  334 LEU LEU B . n 
A 1 356 GLY 356 335  335 GLY GLY B . n 
A 1 357 ASP 357 336  336 ASP ASP B . n 
A 1 358 LEU 358 337  337 LEU LEU B . n 
A 1 359 ALA 359 338  338 ALA ALA B . n 
A 1 360 SER 360 339  339 SER SER B . n 
A 1 361 SER 361 340  340 SER SER B . n 
A 1 362 ASP 362 341  341 ASP ASP B . n 
A 1 363 VAL 363 342  342 VAL VAL B . n 
A 1 364 ALA 364 343  343 ALA ALA B . n 
A 1 365 VAL 365 344  344 VAL VAL B . n 
A 1 366 GLU 366 345  345 GLU GLU B . n 
A 1 367 LEU 367 346  346 LEU LEU B . n 
A 1 368 PRO 368 347  347 PRO PRO B . n 
A 1 369 PHE 369 348  348 PHE PHE B . n 
A 1 370 THR 370 349  349 THR THR B . n 
A 1 371 LEU 371 350  350 LEU LEU B . n 
A 1 372 MET 372 351  351 MET MET B . n 
A 1 373 HIS 373 352  352 HIS HIS B . n 
A 1 374 PRO 374 353  353 PRO PRO B . n 
A 1 375 LYS 375 354  354 LYS LYS B . n 
A 1 376 PRO 376 355  355 PRO PRO B . n 
A 1 377 LYS 377 356  356 LYS LYS B . n 
A 1 378 GLU 378 357  357 GLU GLU B . n 
A 1 379 GLU 379 358  358 GLU GLU B . n 
A 1 380 PRO 380 359  359 PRO PRO B . n 
A 1 381 PRO 381 360  360 PRO PRO B . n 
A 1 382 HIS 382 361  361 HIS HIS B . n 
A 1 383 ARG 383 362  362 ARG ARG B . n 
A 1 384 GLU 384 363  363 GLU GLU B . n 
A 1 385 VAL 385 364  364 VAL VAL B . n 
A 1 386 PRO 386 365  365 PRO PRO B . n 
A 1 387 GLU 387 366  ?   ?   ?   B . n 
A 1 388 ASN 388 367  ?   ?   ?   B . n 
A 1 389 GLU 389 368  ?   ?   ?   B . n 
A 1 390 THR 390 369  ?   ?   ?   B . n 
A 1 391 PRO 391 370  ?   ?   ?   B . n 
A 1 392 VAL 392 371  ?   ?   ?   B . n 
A 1 393 ASP 393 372  ?   ?   ?   B . n 
A 1 394 THR 394 373  ?   ?   ?   B . n 
A 1 395 ASN 395 374  ?   ?   ?   B . n 
A 1 396 LEU 396 375  ?   ?   ?   B . n 
A 1 397 ILE 397 376  ?   ?   ?   B . n 
A 1 398 GLU 398 377  ?   ?   ?   B . n 
A 1 399 LEU 399 378  ?   ?   ?   B . n 
A 1 400 ASP 400 379  ?   ?   ?   B . n 
A 1 401 THR 401 380  ?   ?   ?   B . n 
A 1 402 ASN 402 381  ?   ?   ?   B . n 
B 2 1   MET 1   1    ?   ?   ?   D . n 
B 2 2   VAL 2   2    ?   ?   ?   D . n 
B 2 3   SER 3   3    ?   ?   ?   D . n 
B 2 4   ALA 4   4    ?   ?   ?   D . n 
B 2 5   ILE 5   5    ?   ?   ?   D . n 
B 2 6   VAL 6   6    ?   ?   ?   D . n 
B 2 7   LEU 7   7    ?   ?   ?   D . n 
B 2 8   TYR 8   8    ?   ?   ?   D . n 
B 2 9   VAL 9   9    ?   ?   ?   D . n 
B 2 10  LEU 10  10   ?   ?   ?   D . n 
B 2 11  LEU 11  11   ?   ?   ?   D . n 
B 2 12  ALA 12  12   ?   ?   ?   D . n 
B 2 13  ALA 13  13   ?   ?   ?   D . n 
B 2 14  ALA 14  14   ?   ?   ?   D . n 
B 2 15  ALA 15  15   ?   ?   ?   D . n 
B 2 16  HIS 16  16   ?   ?   ?   D . n 
B 2 17  SER 17  17   ?   ?   ?   D . n 
B 2 18  ALA 18  18   ?   ?   ?   D . n 
B 2 19  PHE 19  19   ?   ?   ?   D . n 
B 2 20  ALA 20  20   ?   ?   ?   D . n 
B 2 21  GLU 21  21   ?   ?   ?   D . n 
B 2 22  ILE 22  22   ?   ?   ?   D . n 
B 2 23  SER 23  23   ?   ?   ?   D . n 
B 2 24  GLU 24  24   24  GLU GLU D . n 
B 2 25  VAL 25  25   25  VAL VAL D . n 
B 2 26  GLN 26  26   26  GLN GLN D . n 
B 2 27  LEU 27  27   27  LEU LEU D . n 
B 2 28  VAL 28  28   28  VAL VAL D . n 
B 2 29  GLU 29  29   29  GLU GLU D . n 
B 2 30  SER 30  30   30  SER SER D . n 
B 2 31  GLY 31  31   31  GLY GLY D . n 
B 2 32  GLY 32  32   32  GLY GLY D . n 
B 2 33  GLY 33  33   33  GLY GLY D . n 
B 2 34  LEU 34  34   34  LEU LEU D . n 
B 2 35  VAL 35  35   35  VAL VAL D . n 
B 2 36  GLN 36  36   36  GLN GLN D . n 
B 2 37  PRO 37  37   37  PRO PRO D . n 
B 2 38  GLY 38  38   38  GLY GLY D . n 
B 2 39  GLY 39  39   39  GLY GLY D . n 
B 2 40  SER 40  40   40  SER SER D . n 
B 2 41  LEU 41  41   41  LEU LEU D . n 
B 2 42  ARG 42  42   42  ARG ARG D . n 
B 2 43  LEU 43  43   43  LEU LEU D . n 
B 2 44  SER 44  44   44  SER SER D . n 
B 2 45  CYS 45  45   45  CYS CYS D . n 
B 2 46  ALA 46  46   46  ALA ALA D . n 
B 2 47  ALA 47  47   47  ALA ALA D . n 
B 2 48  SER 48  48   48  SER SER D . n 
B 2 49  GLY 49  49   49  GLY GLY D . n 
B 2 50  PHE 50  50   50  PHE PHE D . n 
B 2 51  ASN 51  51   51  ASN ASN D . n 
B 2 52  VAL 52  52   52  VAL VAL D . n 
B 2 53  TYR 53  53   53  TYR TYR D . n 
B 2 54  SER 54  54   54  SER SER D . n 
B 2 55  SER 55  55   55  SER SER D . n 
B 2 56  SER 56  56   56  SER SER D . n 
B 2 57  ILE 57  57   57  ILE ILE D . n 
B 2 58  HIS 58  58   58  HIS HIS D . n 
B 2 59  TRP 59  59   59  TRP TRP D . n 
B 2 60  VAL 60  60   60  VAL VAL D . n 
B 2 61  ARG 61  61   61  ARG ARG D . n 
B 2 62  GLN 62  62   62  GLN GLN D . n 
B 2 63  ALA 63  63   63  ALA ALA D . n 
B 2 64  PRO 64  64   64  PRO PRO D . n 
B 2 65  GLY 65  65   65  GLY GLY D . n 
B 2 66  LYS 66  66   66  LYS LYS D . n 
B 2 67  GLY 67  67   67  GLY GLY D . n 
B 2 68  LEU 68  68   68  LEU LEU D . n 
B 2 69  GLU 69  69   69  GLU GLU D . n 
B 2 70  TRP 70  70   70  TRP TRP D . n 
B 2 71  VAL 71  71   71  VAL VAL D . n 
B 2 72  ALA 72  72   72  ALA ALA D . n 
B 2 73  SER 73  73   73  SER SER D . n 
B 2 74  ILE 74  74   74  ILE ILE D . n 
B 2 75  SER 75  75   75  SER SER D . n 
B 2 76  SER 76  76   76  SER SER D . n 
B 2 77  TYR 77  77   77  TYR TYR D . n 
B 2 78  TYR 78  78   78  TYR TYR D . n 
B 2 79  GLY 79  79   79  GLY GLY D . n 
B 2 80  TYR 80  80   80  TYR TYR D . n 
B 2 81  THR 81  81   81  THR THR D . n 
B 2 82  TYR 82  82   82  TYR TYR D . n 
B 2 83  TYR 83  83   83  TYR TYR D . n 
B 2 84  ALA 84  84   84  ALA ALA D . n 
B 2 85  ASP 85  85   85  ASP ASP D . n 
B 2 86  SER 86  86   86  SER SER D . n 
B 2 87  VAL 87  87   87  VAL VAL D . n 
B 2 88  LYS 88  88   88  LYS LYS D . n 
B 2 89  GLY 89  89   89  GLY GLY D . n 
B 2 90  ARG 90  90   90  ARG ARG D . n 
B 2 91  PHE 91  91   91  PHE PHE D . n 
B 2 92  THR 92  92   92  THR THR D . n 
B 2 93  ILE 93  93   93  ILE ILE D . n 
B 2 94  SER 94  94   94  SER SER D . n 
B 2 95  ALA 95  95   95  ALA ALA D . n 
B 2 96  ASP 96  96   96  ASP ASP D . n 
B 2 97  THR 97  97   97  THR THR D . n 
B 2 98  SER 98  98   98  SER SER D . n 
B 2 99  LYS 99  99   99  LYS LYS D . n 
B 2 100 ASN 100 100  100 ASN ASN D . n 
B 2 101 THR 101 101  101 THR THR D . n 
B 2 102 ALA 102 102  102 ALA ALA D . n 
B 2 103 TYR 103 103  103 TYR TYR D . n 
B 2 104 LEU 104 104  104 LEU LEU D . n 
B 2 105 GLN 105 105  105 GLN GLN D . n 
B 2 106 MET 106 106  106 MET MET D . n 
B 2 107 ASN 107 107  107 ASN ASN D . n 
B 2 108 SER 108 108  108 SER SER D . n 
B 2 109 LEU 109 109  109 LEU LEU D . n 
B 2 110 ARG 110 110  110 ARG ARG D . n 
B 2 111 ALA 111 111  111 ALA ALA D . n 
B 2 112 GLU 112 112  112 GLU GLU D . n 
B 2 113 ASP 113 113  113 ASP ASP D . n 
B 2 114 THR 114 114  114 THR THR D . n 
B 2 115 ALA 115 115  115 ALA ALA D . n 
B 2 116 VAL 116 116  116 VAL VAL D . n 
B 2 117 TYR 117 117  117 TYR TYR D . n 
B 2 118 TYR 118 118  118 TYR TYR D . n 
B 2 119 CYS 119 119  119 CYS CYS D . n 
B 2 120 ALA 120 120  120 ALA ALA D . n 
B 2 121 ARG 121 121  121 ARG ARG D . n 
B 2 122 SER 122 122  122 SER SER D . n 
B 2 123 ARG 123 123  123 ARG ARG D . n 
B 2 124 GLN 124 124  124 GLN GLN D . n 
B 2 125 PHE 125 125  125 PHE PHE D . n 
B 2 126 TRP 126 126  126 TRP TRP D . n 
B 2 127 TYR 127 127  127 TYR TYR D . n 
B 2 128 SER 128 128  128 SER SER D . n 
B 2 129 GLY 129 129  129 GLY GLY D . n 
B 2 130 LEU 130 130  130 LEU LEU D . n 
B 2 131 ASP 131 131  131 ASP ASP D . n 
B 2 132 TYR 132 132  132 TYR TYR D . n 
B 2 133 TRP 133 133  133 TRP TRP D . n 
B 2 134 GLY 134 134  134 GLY GLY D . n 
B 2 135 GLN 135 135  135 GLN GLN D . n 
B 2 136 GLY 136 136  136 GLY GLY D . n 
B 2 137 THR 137 137  137 THR THR D . n 
B 2 138 LEU 138 138  138 LEU LEU D . n 
B 2 139 VAL 139 139  139 VAL VAL D . n 
B 2 140 THR 140 140  140 THR THR D . n 
B 2 141 VAL 141 141  141 VAL VAL D . n 
B 2 142 SER 142 142  142 SER SER D . n 
B 2 143 SER 143 143  143 SER SER D . n 
B 2 144 ALA 144 144  144 ALA ALA D . n 
B 2 145 SER 145 145  145 SER SER D . n 
B 2 146 THR 146 146  146 THR THR D . n 
B 2 147 LYS 147 147  147 LYS LYS D . n 
B 2 148 GLY 148 148  148 GLY GLY D . n 
B 2 149 PRO 149 149  149 PRO PRO D . n 
B 2 150 SER 150 150  150 SER SER D . n 
B 2 151 VAL 151 151  151 VAL VAL D . n 
B 2 152 PHE 152 152  152 PHE PHE D . n 
B 2 153 PRO 153 153  153 PRO PRO D . n 
B 2 154 LEU 154 154  154 LEU LEU D . n 
B 2 155 ALA 155 155  155 ALA ALA D . n 
B 2 156 PRO 156 156  156 PRO PRO D . n 
B 2 157 SER 157 157  157 SER SER D . n 
B 2 158 SER 158 158  158 SER SER D . n 
B 2 159 LYS 159 159  159 LYS LYS D . n 
B 2 160 SER 160 160  160 SER SER D . n 
B 2 161 THR 161 161  161 THR THR D . n 
B 2 162 SER 162 162  162 SER SER D . n 
B 2 163 GLY 163 163  163 GLY GLY D . n 
B 2 164 GLY 164 164  164 GLY GLY D . n 
B 2 165 THR 165 165  165 THR THR D . n 
B 2 166 ALA 166 166  166 ALA ALA D . n 
B 2 167 ALA 167 167  167 ALA ALA D . n 
B 2 168 LEU 168 168  168 LEU LEU D . n 
B 2 169 GLY 169 169  169 GLY GLY D . n 
B 2 170 CYS 170 170  170 CYS CYS D . n 
B 2 171 LEU 171 171  171 LEU LEU D . n 
B 2 172 VAL 172 172  172 VAL VAL D . n 
B 2 173 LYS 173 173  173 LYS LYS D . n 
B 2 174 ASP 174 174  174 ASP ASP D . n 
B 2 175 TYR 175 175  175 TYR TYR D . n 
B 2 176 PHE 176 176  176 PHE PHE D . n 
B 2 177 PRO 177 177  177 PRO PRO D . n 
B 2 178 GLU 178 178  178 GLU GLU D . n 
B 2 179 PRO 179 179  179 PRO PRO D . n 
B 2 180 VAL 180 180  180 VAL VAL D . n 
B 2 181 THR 181 181  181 THR THR D . n 
B 2 182 VAL 182 182  182 VAL VAL D . n 
B 2 183 SER 183 183  183 SER SER D . n 
B 2 184 TRP 184 184  184 TRP TRP D . n 
B 2 185 ASN 185 185  185 ASN ASN D . n 
B 2 186 SER 186 186  186 SER SER D . n 
B 2 187 GLY 187 187  187 GLY GLY D . n 
B 2 188 ALA 188 188  188 ALA ALA D . n 
B 2 189 LEU 189 189  189 LEU LEU D . n 
B 2 190 THR 190 190  190 THR THR D . n 
B 2 191 SER 191 191  191 SER SER D . n 
B 2 192 GLY 192 192  192 GLY GLY D . n 
B 2 193 VAL 193 193  193 VAL VAL D . n 
B 2 194 HIS 194 194  194 HIS HIS D . n 
B 2 195 THR 195 195  195 THR THR D . n 
B 2 196 PHE 196 196  196 PHE PHE D . n 
B 2 197 PRO 197 197  197 PRO PRO D . n 
B 2 198 ALA 198 198  198 ALA ALA D . n 
B 2 199 VAL 199 199  199 VAL VAL D . n 
B 2 200 LEU 200 200  200 LEU LEU D . n 
B 2 201 GLN 201 201  201 GLN GLN D . n 
B 2 202 SER 202 202  202 SER SER D . n 
B 2 203 SER 203 203  203 SER SER D . n 
B 2 204 GLY 204 204  204 GLY GLY D . n 
B 2 205 LEU 205 205  205 LEU LEU D . n 
B 2 206 TYR 206 206  206 TYR TYR D . n 
B 2 207 SER 207 207  207 SER SER D . n 
B 2 208 LEU 208 208  208 LEU LEU D . n 
B 2 209 SER 209 209  209 SER SER D . n 
B 2 210 SER 210 210  210 SER SER D . n 
B 2 211 VAL 211 211  211 VAL VAL D . n 
B 2 212 VAL 212 212  212 VAL VAL D . n 
B 2 213 THR 213 213  213 THR THR D . n 
B 2 214 VAL 214 214  214 VAL VAL D . n 
B 2 215 PRO 215 215  215 PRO PRO D . n 
B 2 216 SER 216 216  216 SER SER D . n 
B 2 217 SER 217 217  217 SER SER D . n 
B 2 218 SER 218 218  218 SER SER D . n 
B 2 219 LEU 219 219  219 LEU LEU D . n 
B 2 220 GLY 220 220  220 GLY GLY D . n 
B 2 221 THR 221 221  221 THR THR D . n 
B 2 222 GLN 222 222  222 GLN GLN D . n 
B 2 223 THR 223 223  223 THR THR D . n 
B 2 224 TYR 224 224  224 TYR TYR D . n 
B 2 225 ILE 225 225  225 ILE ILE D . n 
B 2 226 CYS 226 226  226 CYS CYS D . n 
B 2 227 ASN 227 227  227 ASN ASN D . n 
B 2 228 VAL 228 228  228 VAL VAL D . n 
B 2 229 ASN 229 229  229 ASN ASN D . n 
B 2 230 HIS 230 230  230 HIS HIS D . n 
B 2 231 LYS 231 231  231 LYS LYS D . n 
B 2 232 PRO 232 232  232 PRO PRO D . n 
B 2 233 SER 233 233  233 SER SER D . n 
B 2 234 ASN 234 234  234 ASN ASN D . n 
B 2 235 THR 235 235  235 THR THR D . n 
B 2 236 LYS 236 236  236 LYS LYS D . n 
B 2 237 VAL 237 237  237 VAL VAL D . n 
B 2 238 ASP 238 238  238 ASP ASP D . n 
B 2 239 LYS 239 239  239 LYS LYS D . n 
B 2 240 LYS 240 240  240 LYS LYS D . n 
B 2 241 VAL 241 241  241 VAL VAL D . n 
B 2 242 GLU 242 242  242 GLU GLU D . n 
B 2 243 PRO 243 243  243 PRO PRO D . n 
B 2 244 LYS 244 244  244 LYS LYS D . n 
B 2 245 SER 245 245  ?   ?   ?   D . n 
B 2 246 CYS 246 246  ?   ?   ?   D . n 
B 2 247 ASP 247 247  ?   ?   ?   D . n 
B 2 248 LYS 248 248  ?   ?   ?   D . n 
B 2 249 THR 249 249  ?   ?   ?   D . n 
B 2 250 ALA 250 250  ?   ?   ?   D . n 
B 2 251 ALA 251 251  ?   ?   ?   D . n 
B 2 252 ALA 252 252  ?   ?   ?   D . n 
B 2 253 HIS 253 253  ?   ?   ?   D . n 
B 2 254 HIS 254 254  ?   ?   ?   D . n 
B 2 255 HIS 255 255  ?   ?   ?   D . n 
B 2 256 HIS 256 256  ?   ?   ?   D . n 
B 2 257 HIS 257 257  ?   ?   ?   D . n 
B 2 258 HIS 258 258  ?   ?   ?   D . n 
B 2 259 HIS 259 259  ?   ?   ?   D . n 
B 2 260 HIS 260 260  ?   ?   ?   D . n 
C 3 1   MET 1   1    ?   ?   ?   Q . n 
C 3 2   VAL 2   2    ?   ?   ?   Q . n 
C 3 3   SER 3   3    ?   ?   ?   Q . n 
C 3 4   ALA 4   4    ?   ?   ?   Q . n 
C 3 5   ILE 5   5    ?   ?   ?   Q . n 
C 3 6   VAL 6   6    ?   ?   ?   Q . n 
C 3 7   LEU 7   7    ?   ?   ?   Q . n 
C 3 8   TYR 8   8    ?   ?   ?   Q . n 
C 3 9   VAL 9   9    ?   ?   ?   Q . n 
C 3 10  LEU 10  10   ?   ?   ?   Q . n 
C 3 11  LEU 11  11   ?   ?   ?   Q . n 
C 3 12  ALA 12  12   ?   ?   ?   Q . n 
C 3 13  ALA 13  13   ?   ?   ?   Q . n 
C 3 14  ALA 14  14   ?   ?   ?   Q . n 
C 3 15  ALA 15  15   ?   ?   ?   Q . n 
C 3 16  HIS 16  16   ?   ?   ?   Q . n 
C 3 17  SER 17  17   ?   ?   ?   Q . n 
C 3 18  ALA 18  18   ?   ?   ?   Q . n 
C 3 19  PHE 19  19   ?   ?   ?   Q . n 
C 3 20  ALA 20  20   20  ALA ALA Q . n 
C 3 21  SER 21  21   21  SER SER Q . n 
C 3 22  ASP 22  22   22  ASP ASP Q . n 
C 3 23  ILE 23  23   23  ILE ILE Q . n 
C 3 24  GLN 24  24   24  GLN GLN Q . n 
C 3 25  MET 25  25   25  MET MET Q . n 
C 3 26  THR 26  26   26  THR THR Q . n 
C 3 27  GLN 27  27   27  GLN GLN Q . n 
C 3 28  SER 28  28   28  SER SER Q . n 
C 3 29  PRO 29  29   29  PRO PRO Q . n 
C 3 30  SER 30  30   30  SER SER Q . n 
C 3 31  SER 31  31   31  SER SER Q . n 
C 3 32  LEU 32  32   32  LEU LEU Q . n 
C 3 33  SER 33  33   33  SER SER Q . n 
C 3 34  ALA 34  34   34  ALA ALA Q . n 
C 3 35  SER 35  35   35  SER SER Q . n 
C 3 36  VAL 36  36   36  VAL VAL Q . n 
C 3 37  GLY 37  37   37  GLY GLY Q . n 
C 3 38  ASP 38  38   38  ASP ASP Q . n 
C 3 39  ARG 39  39   39  ARG ARG Q . n 
C 3 40  VAL 40  40   40  VAL VAL Q . n 
C 3 41  THR 41  41   41  THR THR Q . n 
C 3 42  ILE 42  42   42  ILE ILE Q . n 
C 3 43  THR 43  43   43  THR THR Q . n 
C 3 44  CYS 44  44   44  CYS CYS Q . n 
C 3 45  ARG 45  45   45  ARG ARG Q . n 
C 3 46  ALA 46  46   46  ALA ALA Q . n 
C 3 47  SER 47  47   47  SER SER Q . n 
C 3 48  GLN 48  48   48  GLN GLN Q . n 
C 3 49  SER 49  49   49  SER SER Q . n 
C 3 50  VAL 50  50   50  VAL VAL Q . n 
C 3 51  SER 51  51   51  SER SER Q . n 
C 3 52  SER 52  52   52  SER SER Q . n 
C 3 53  ALA 53  53   53  ALA ALA Q . n 
C 3 54  VAL 54  54   54  VAL VAL Q . n 
C 3 55  ALA 55  55   55  ALA ALA Q . n 
C 3 56  TRP 56  56   56  TRP TRP Q . n 
C 3 57  TYR 57  57   57  TYR TYR Q . n 
C 3 58  GLN 58  58   58  GLN GLN Q . n 
C 3 59  GLN 59  59   59  GLN GLN Q . n 
C 3 60  LYS 60  60   60  LYS LYS Q . n 
C 3 61  PRO 61  61   61  PRO PRO Q . n 
C 3 62  GLY 62  62   62  GLY GLY Q . n 
C 3 63  LYS 63  63   63  LYS LYS Q . n 
C 3 64  ALA 64  64   64  ALA ALA Q . n 
C 3 65  PRO 65  65   65  PRO PRO Q . n 
C 3 66  LYS 66  66   66  LYS LYS Q . n 
C 3 67  LEU 67  67   67  LEU LEU Q . n 
C 3 68  LEU 68  68   68  LEU LEU Q . n 
C 3 69  ILE 69  69   69  ILE ILE Q . n 
C 3 70  TYR 70  70   70  TYR TYR Q . n 
C 3 71  SER 71  71   71  SER SER Q . n 
C 3 72  ALA 72  72   72  ALA ALA Q . n 
C 3 73  SER 73  73   73  SER SER Q . n 
C 3 74  SER 74  74   74  SER SER Q . n 
C 3 75  LEU 75  75   75  LEU LEU Q . n 
C 3 76  TYR 76  76   76  TYR TYR Q . n 
C 3 77  SER 77  77   77  SER SER Q . n 
C 3 78  GLY 78  78   78  GLY GLY Q . n 
C 3 79  VAL 79  79   79  VAL VAL Q . n 
C 3 80  PRO 80  80   80  PRO PRO Q . n 
C 3 81  SER 81  81   81  SER SER Q . n 
C 3 82  ARG 82  82   82  ARG ARG Q . n 
C 3 83  PHE 83  83   83  PHE PHE Q . n 
C 3 84  SER 84  84   84  SER SER Q . n 
C 3 85  GLY 85  85   85  GLY GLY Q . n 
C 3 86  SER 86  86   86  SER SER Q . n 
C 3 87  ARG 87  87   87  ARG ARG Q . n 
C 3 88  SER 88  88   88  SER SER Q . n 
C 3 89  GLY 89  89   89  GLY GLY Q . n 
C 3 90  THR 90  90   90  THR THR Q . n 
C 3 91  ASP 91  91   91  ASP ASP Q . n 
C 3 92  PHE 92  92   92  PHE PHE Q . n 
C 3 93  THR 93  93   93  THR THR Q . n 
C 3 94  LEU 94  94   94  LEU LEU Q . n 
C 3 95  THR 95  95   95  THR THR Q . n 
C 3 96  ILE 96  96   96  ILE ILE Q . n 
C 3 97  SER 97  97   97  SER SER Q . n 
C 3 98  SER 98  98   98  SER SER Q . n 
C 3 99  LEU 99  99   99  LEU LEU Q . n 
C 3 100 GLN 100 100  100 GLN GLN Q . n 
C 3 101 PRO 101 101  101 PRO PRO Q . n 
C 3 102 GLU 102 102  102 GLU GLU Q . n 
C 3 103 ASP 103 103  103 ASP ASP Q . n 
C 3 104 PHE 104 104  104 PHE PHE Q . n 
C 3 105 ALA 105 105  105 ALA ALA Q . n 
C 3 106 THR 106 106  106 THR THR Q . n 
C 3 107 TYR 107 107  107 TYR TYR Q . n 
C 3 108 TYR 108 108  108 TYR TYR Q . n 
C 3 109 CYS 109 109  109 CYS CYS Q . n 
C 3 110 GLN 110 110  110 GLN GLN Q . n 
C 3 111 GLN 111 111  111 GLN GLN Q . n 
C 3 112 TYR 112 112  112 TYR TYR Q . n 
C 3 113 LYS 113 113  113 LYS LYS Q . n 
C 3 114 TYR 114 114  114 TYR TYR Q . n 
C 3 115 VAL 115 115  115 VAL VAL Q . n 
C 3 116 PRO 116 116  116 PRO PRO Q . n 
C 3 117 VAL 117 117  117 VAL VAL Q . n 
C 3 118 THR 118 118  118 THR THR Q . n 
C 3 119 PHE 119 119  119 PHE PHE Q . n 
C 3 120 GLY 120 120  120 GLY GLY Q . n 
C 3 121 GLN 121 121  121 GLN GLN Q . n 
C 3 122 GLY 122 122  122 GLY GLY Q . n 
C 3 123 THR 123 123  123 THR THR Q . n 
C 3 124 LYS 124 124  124 LYS LYS Q . n 
C 3 125 VAL 125 125  125 VAL VAL Q . n 
C 3 126 GLU 126 126  126 GLU GLU Q . n 
C 3 127 ILE 127 127  127 ILE ILE Q . n 
C 3 128 LYS 128 128  128 LYS LYS Q . n 
C 3 129 ARG 129 129  129 ARG ARG Q . n 
C 3 130 THR 130 130  130 THR THR Q . n 
C 3 131 VAL 131 131  131 VAL VAL Q . n 
C 3 132 ALA 132 132  132 ALA ALA Q . n 
C 3 133 ALA 133 133  133 ALA ALA Q . n 
C 3 134 PRO 134 134  134 PRO PRO Q . n 
C 3 135 SER 135 135  135 SER SER Q . n 
C 3 136 VAL 136 136  136 VAL VAL Q . n 
C 3 137 PHE 137 137  137 PHE PHE Q . n 
C 3 138 ILE 138 138  138 ILE ILE Q . n 
C 3 139 PHE 139 139  139 PHE PHE Q . n 
C 3 140 PRO 140 140  140 PRO PRO Q . n 
C 3 141 PRO 141 141  141 PRO PRO Q . n 
C 3 142 SER 142 142  142 SER SER Q . n 
C 3 143 ASP 143 143  143 ASP ASP Q . n 
C 3 144 SER 144 144  144 SER SER Q . n 
C 3 145 GLN 145 145  145 GLN GLN Q . n 
C 3 146 LEU 146 146  146 LEU LEU Q . n 
C 3 147 LYS 147 147  147 LYS LYS Q . n 
C 3 148 SER 148 148  148 SER SER Q . n 
C 3 149 GLY 149 149  149 GLY GLY Q . n 
C 3 150 THR 150 150  150 THR THR Q . n 
C 3 151 ALA 151 151  151 ALA ALA Q . n 
C 3 152 SER 152 152  152 SER SER Q . n 
C 3 153 VAL 153 153  153 VAL VAL Q . n 
C 3 154 VAL 154 154  154 VAL VAL Q . n 
C 3 155 CYS 155 155  155 CYS CYS Q . n 
C 3 156 LEU 156 156  156 LEU LEU Q . n 
C 3 157 LEU 157 157  157 LEU LEU Q . n 
C 3 158 ASN 158 158  158 ASN ASN Q . n 
C 3 159 ASN 159 159  159 ASN ASN Q . n 
C 3 160 PHE 160 160  160 PHE PHE Q . n 
C 3 161 TYR 161 161  161 TYR TYR Q . n 
C 3 162 PRO 162 162  162 PRO PRO Q . n 
C 3 163 ARG 163 163  163 ARG ARG Q . n 
C 3 164 GLU 164 164  164 GLU GLU Q . n 
C 3 165 ALA 165 165  165 ALA ALA Q . n 
C 3 166 LYS 166 166  166 LYS LYS Q . n 
C 3 167 VAL 167 167  167 VAL VAL Q . n 
C 3 168 GLN 168 168  168 GLN GLN Q . n 
C 3 169 TRP 169 169  169 TRP TRP Q . n 
C 3 170 LYS 170 170  170 LYS LYS Q . n 
C 3 171 VAL 171 171  171 VAL VAL Q . n 
C 3 172 ASP 172 172  172 ASP ASP Q . n 
C 3 173 ASN 173 173  173 ASN ASN Q . n 
C 3 174 ALA 174 174  174 ALA ALA Q . n 
C 3 175 LEU 175 175  175 LEU LEU Q . n 
C 3 176 GLN 176 176  176 GLN GLN Q . n 
C 3 177 SER 177 177  177 SER SER Q . n 
C 3 178 GLY 178 178  178 GLY GLY Q . n 
C 3 179 ASN 179 179  179 ASN ASN Q . n 
C 3 180 SER 180 180  180 SER SER Q . n 
C 3 181 GLN 181 181  181 GLN GLN Q . n 
C 3 182 GLU 182 182  182 GLU GLU Q . n 
C 3 183 SER 183 183  183 SER SER Q . n 
C 3 184 VAL 184 184  184 VAL VAL Q . n 
C 3 185 THR 185 185  185 THR THR Q . n 
C 3 186 GLU 186 186  186 GLU GLU Q . n 
C 3 187 GLN 187 187  187 GLN GLN Q . n 
C 3 188 ASP 188 188  188 ASP ASP Q . n 
C 3 189 SER 189 189  189 SER SER Q . n 
C 3 190 LYS 190 190  190 LYS LYS Q . n 
C 3 191 ASP 191 191  191 ASP ASP Q . n 
C 3 192 SER 192 192  192 SER SER Q . n 
C 3 193 THR 193 193  193 THR THR Q . n 
C 3 194 TYR 194 194  194 TYR TYR Q . n 
C 3 195 SER 195 195  195 SER SER Q . n 
C 3 196 LEU 196 196  196 LEU LEU Q . n 
C 3 197 SER 197 197  197 SER SER Q . n 
C 3 198 SER 198 198  198 SER SER Q . n 
C 3 199 THR 199 199  199 THR THR Q . n 
C 3 200 LEU 200 200  200 LEU LEU Q . n 
C 3 201 THR 201 201  201 THR THR Q . n 
C 3 202 LEU 202 202  202 LEU LEU Q . n 
C 3 203 SER 203 203  203 SER SER Q . n 
C 3 204 LYS 204 204  204 LYS LYS Q . n 
C 3 205 ALA 205 205  205 ALA ALA Q . n 
C 3 206 ASP 206 206  206 ASP ASP Q . n 
C 3 207 TYR 207 207  207 TYR TYR Q . n 
C 3 208 GLU 208 208  208 GLU GLU Q . n 
C 3 209 LYS 209 209  209 LYS LYS Q . n 
C 3 210 HIS 210 210  210 HIS HIS Q . n 
C 3 211 LYS 211 211  211 LYS LYS Q . n 
C 3 212 VAL 212 212  212 VAL VAL Q . n 
C 3 213 TYR 213 213  213 TYR TYR Q . n 
C 3 214 ALA 214 214  214 ALA ALA Q . n 
C 3 215 CYS 215 215  215 CYS CYS Q . n 
C 3 216 GLU 216 216  216 GLU GLU Q . n 
C 3 217 VAL 217 217  217 VAL VAL Q . n 
C 3 218 THR 218 218  218 THR THR Q . n 
C 3 219 HIS 219 219  219 HIS HIS Q . n 
C 3 220 GLN 220 220  220 GLN GLN Q . n 
C 3 221 GLY 221 221  221 GLY GLY Q . n 
C 3 222 LEU 222 222  222 LEU LEU Q . n 
C 3 223 SER 223 223  223 SER SER Q . n 
C 3 224 SER 224 224  224 SER SER Q . n 
C 3 225 PRO 225 225  225 PRO PRO Q . n 
C 3 226 VAL 226 226  226 VAL VAL Q . n 
C 3 227 THR 227 227  227 THR THR Q . n 
C 3 228 LYS 228 228  228 LYS LYS Q . n 
C 3 229 SER 229 229  229 SER SER Q . n 
C 3 230 PHE 230 230  230 PHE PHE Q . n 
C 3 231 ASN 231 231  231 ASN ASN Q . n 
C 3 232 ARG 232 232  232 ARG ARG Q . n 
C 3 233 GLY 233 233  233 GLY GLY Q . n 
C 3 234 GLU 234 234  234 GLU GLU Q . n 
C 3 235 CYS 235 235  235 CYS CYS Q . n 
D 4 1   MET 1   -135 ?   ?   ?   R . n 
D 4 2   LYS 2   -134 ?   ?   ?   R . n 
D 4 3   THR 3   -133 ?   ?   ?   R . n 
D 4 4   ILE 4   -132 ?   ?   ?   R . n 
D 4 5   ILE 5   -131 ?   ?   ?   R . n 
D 4 6   ALA 6   -130 ?   ?   ?   R . n 
D 4 7   LEU 7   -129 ?   ?   ?   R . n 
D 4 8   SER 8   -128 ?   ?   ?   R . n 
D 4 9   TYR 9   -127 ?   ?   ?   R . n 
D 4 10  ILE 10  -126 ?   ?   ?   R . n 
D 4 11  PHE 11  -125 ?   ?   ?   R . n 
D 4 12  CYS 12  -124 ?   ?   ?   R . n 
D 4 13  LEU 13  -123 ?   ?   ?   R . n 
D 4 14  VAL 14  -122 ?   ?   ?   R . n 
D 4 15  PHE 15  -121 ?   ?   ?   R . n 
D 4 16  ALA 16  -120 ?   ?   ?   R . n 
D 4 17  GLY 17  -119 ?   ?   ?   R . n 
D 4 18  SER 18  -118 ?   ?   ?   R . n 
D 4 19  ALA 19  -117 ?   ?   ?   R . n 
D 4 20  ASP 20  -116 ?   ?   ?   R . n 
D 4 21  LEU 21  -115 ?   ?   ?   R . n 
D 4 22  GLU 22  -114 ?   ?   ?   R . n 
D 4 23  ASP 23  -113 ?   ?   ?   R . n 
D 4 24  ASN 24  -112 ?   ?   ?   R . n 
D 4 25  TRP 25  -111 ?   ?   ?   R . n 
D 4 26  GLU 26  -110 ?   ?   ?   R . n 
D 4 27  THR 27  -109 ?   ?   ?   R . n 
D 4 28  LEU 28  -108 ?   ?   ?   R . n 
D 4 29  ASN 29  -107 ?   ?   ?   R . n 
D 4 30  ASP 30  -106 ?   ?   ?   R . n 
D 4 31  ASN 31  -105 ?   ?   ?   R . n 
D 4 32  LEU 32  -104 ?   ?   ?   R . n 
D 4 33  LYS 33  -103 ?   ?   ?   R . n 
D 4 34  VAL 34  -102 ?   ?   ?   R . n 
D 4 35  ILE 35  -101 ?   ?   ?   R . n 
D 4 36  GLU 36  -100 ?   ?   ?   R . n 
D 4 37  LYS 37  -99  ?   ?   ?   R . n 
D 4 38  ALA 38  -98  ?   ?   ?   R . n 
D 4 39  ASP 39  -97  ?   ?   ?   R . n 
D 4 40  ASN 40  -96  ?   ?   ?   R . n 
D 4 41  ALA 41  -95  ?   ?   ?   R . n 
D 4 42  ALA 42  -94  ?   ?   ?   R . n 
D 4 43  GLN 43  -93  ?   ?   ?   R . n 
D 4 44  VAL 44  -92  ?   ?   ?   R . n 
D 4 45  LYS 45  -91  ?   ?   ?   R . n 
D 4 46  ASP 46  -90  ?   ?   ?   R . n 
D 4 47  ALA 47  -89  ?   ?   ?   R . n 
D 4 48  LEU 48  -88  ?   ?   ?   R . n 
D 4 49  THR 49  -87  ?   ?   ?   R . n 
D 4 50  LYS 50  -86  ?   ?   ?   R . n 
D 4 51  MET 51  -85  ?   ?   ?   R . n 
D 4 52  ARG 52  -84  ?   ?   ?   R . n 
D 4 53  ALA 53  -83  ?   ?   ?   R . n 
D 4 54  ALA 54  -82  ?   ?   ?   R . n 
D 4 55  ALA 55  -81  ?   ?   ?   R . n 
D 4 56  LEU 56  -80  ?   ?   ?   R . n 
D 4 57  ASP 57  -79  ?   ?   ?   R . n 
D 4 58  ALA 58  -78  ?   ?   ?   R . n 
D 4 59  GLN 59  -77  ?   ?   ?   R . n 
D 4 60  LYS 60  -76  ?   ?   ?   R . n 
D 4 61  ALA 61  -75  ?   ?   ?   R . n 
D 4 62  THR 62  -74  ?   ?   ?   R . n 
D 4 63  PRO 63  -73  ?   ?   ?   R . n 
D 4 64  PRO 64  -72  ?   ?   ?   R . n 
D 4 65  LYS 65  -71  ?   ?   ?   R . n 
D 4 66  LEU 66  -70  ?   ?   ?   R . n 
D 4 67  GLU 67  -69  ?   ?   ?   R . n 
D 4 68  ASP 68  -68  ?   ?   ?   R . n 
D 4 69  LYS 69  -67  ?   ?   ?   R . n 
D 4 70  SER 70  -66  ?   ?   ?   R . n 
D 4 71  PRO 71  -65  ?   ?   ?   R . n 
D 4 72  ASP 72  -64  ?   ?   ?   R . n 
D 4 73  SER 73  -63  ?   ?   ?   R . n 
D 4 74  PRO 74  -62  ?   ?   ?   R . n 
D 4 75  GLU 75  -61  ?   ?   ?   R . n 
D 4 76  MET 76  -60  ?   ?   ?   R . n 
D 4 77  LYS 77  -59  ?   ?   ?   R . n 
D 4 78  ASP 78  -58  ?   ?   ?   R . n 
D 4 79  PHE 79  -57  ?   ?   ?   R . n 
D 4 80  ARG 80  -56  ?   ?   ?   R . n 
D 4 81  HIS 81  -55  ?   ?   ?   R . n 
D 4 82  GLY 82  -54  ?   ?   ?   R . n 
D 4 83  PHE 83  -53  ?   ?   ?   R . n 
D 4 84  ASP 84  -52  ?   ?   ?   R . n 
D 4 85  ILE 85  -51  ?   ?   ?   R . n 
D 4 86  LEU 86  -50  ?   ?   ?   R . n 
D 4 87  VAL 87  -49  ?   ?   ?   R . n 
D 4 88  GLY 88  -48  ?   ?   ?   R . n 
D 4 89  GLN 89  -47  ?   ?   ?   R . n 
D 4 90  ILE 90  -46  ?   ?   ?   R . n 
D 4 91  ASP 91  -45  ?   ?   ?   R . n 
D 4 92  ASP 92  -44  ?   ?   ?   R . n 
D 4 93  ALA 93  -43  ?   ?   ?   R . n 
D 4 94  LEU 94  -42  ?   ?   ?   R . n 
D 4 95  LYS 95  -41  ?   ?   ?   R . n 
D 4 96  LEU 96  -40  ?   ?   ?   R . n 
D 4 97  ALA 97  -39  ?   ?   ?   R . n 
D 4 98  ASN 98  -38  ?   ?   ?   R . n 
D 4 99  GLU 99  -37  ?   ?   ?   R . n 
D 4 100 GLY 100 -36  ?   ?   ?   R . n 
D 4 101 LYS 101 -35  ?   ?   ?   R . n 
D 4 102 VAL 102 -34  ?   ?   ?   R . n 
D 4 103 LYS 103 -33  ?   ?   ?   R . n 
D 4 104 GLU 104 -32  ?   ?   ?   R . n 
D 4 105 ALA 105 -31  ?   ?   ?   R . n 
D 4 106 GLN 106 -30  ?   ?   ?   R . n 
D 4 107 ALA 107 -29  ?   ?   ?   R . n 
D 4 108 ALA 108 -28  ?   ?   ?   R . n 
D 4 109 ALA 109 -27  ?   ?   ?   R . n 
D 4 110 GLU 110 -26  ?   ?   ?   R . n 
D 4 111 GLN 111 -25  ?   ?   ?   R . n 
D 4 112 LEU 112 -24  ?   ?   ?   R . n 
D 4 113 LYS 113 -23  ?   ?   ?   R . n 
D 4 114 THR 114 -22  ?   ?   ?   R . n 
D 4 115 THR 115 -21  ?   ?   ?   R . n 
D 4 116 ARG 116 -20  ?   ?   ?   R . n 
D 4 117 ASN 117 -19  ?   ?   ?   R . n 
D 4 118 ALA 118 -18  ?   ?   ?   R . n 
D 4 119 TYR 119 -17  ?   ?   ?   R . n 
D 4 120 ILE 120 -16  ?   ?   ?   R . n 
D 4 121 GLN 121 -15  ?   ?   ?   R . n 
D 4 122 LYS 122 -14  ?   ?   ?   R . n 
D 4 123 TYR 123 -13  ?   ?   ?   R . n 
D 4 124 LEU 124 -12  ?   ?   ?   R . n 
D 4 125 ALA 125 -11  ?   ?   ?   R . n 
D 4 126 SER 126 -10  ?   ?   ?   R . n 
D 4 127 GLY 127 -9   ?   ?   ?   R . n 
D 4 128 SER 128 -8   ?   ?   ?   R . n 
D 4 129 LEU 129 -7   ?   ?   ?   R . n 
D 4 130 GLU 130 -6   ?   ?   ?   R . n 
D 4 131 VAL 131 -5   ?   ?   ?   R . n 
D 4 132 LEU 132 -4   ?   ?   ?   R . n 
D 4 133 PHE 133 -3   ?   ?   ?   R . n 
D 4 134 GLN 134 -2   ?   ?   ?   R . n 
D 4 135 GLY 135 -1   ?   ?   ?   R . n 
D 4 136 PRO 136 0    ?   ?   ?   R . n 
D 4 137 MET 137 1    ?   ?   ?   R . n 
D 4 138 ARG 138 2    ?   ?   ?   R . n 
D 4 139 LEU 139 3    ?   ?   ?   R . n 
D 4 140 ASN 140 4    ?   ?   ?   R . n 
D 4 141 SER 141 5    ?   ?   ?   R . n 
D 4 142 SER 142 6    ?   ?   ?   R . n 
D 4 143 ALA 143 7    ?   ?   ?   R . n 
D 4 144 PRO 144 8    ?   ?   ?   R . n 
D 4 145 GLY 145 9    ?   ?   ?   R . n 
D 4 146 THR 146 10   ?   ?   ?   R . n 
D 4 147 PRO 147 11   ?   ?   ?   R . n 
D 4 148 GLY 148 12   ?   ?   ?   R . n 
D 4 149 THR 149 13   ?   ?   ?   R . n 
D 4 150 PRO 150 14   ?   ?   ?   R . n 
D 4 151 ALA 151 15   ?   ?   ?   R . n 
D 4 152 ALA 152 16   ?   ?   ?   R . n 
D 4 153 ASP 153 17   ?   ?   ?   R . n 
D 4 154 PRO 154 18   ?   ?   ?   R . n 
D 4 155 PHE 155 19   ?   ?   ?   R . n 
D 4 156 GLN 156 20   ?   ?   ?   R . n 
D 4 157 ARG 157 21   ?   ?   ?   R . n 
D 4 158 ALA 158 22   ?   ?   ?   R . n 
D 4 159 GLN 159 23   ?   ?   ?   R . n 
D 4 160 ALA 160 24   ?   ?   ?   R . n 
D 4 161 GLY 161 25   ?   ?   ?   R . n 
D 4 162 LEU 162 26   ?   ?   ?   R . n 
D 4 163 GLU 163 27   ?   ?   ?   R . n 
D 4 164 GLU 164 28   ?   ?   ?   R . n 
D 4 165 ALA 165 29   ?   ?   ?   R . n 
D 4 166 LEU 166 30   ?   ?   ?   R . n 
D 4 167 LEU 167 31   ?   ?   ?   R . n 
D 4 168 ALA 168 32   ?   ?   ?   R . n 
D 4 169 PRO 169 33   ?   ?   ?   R . n 
D 4 170 GLY 170 34   ?   ?   ?   R . n 
D 4 171 PHE 171 35   ?   ?   ?   R . n 
D 4 172 GLY 172 36   ?   ?   ?   R . n 
D 4 173 ASN 173 37   ?   ?   ?   R . n 
D 4 174 ALA 174 38   ?   ?   ?   R . n 
D 4 175 SER 175 39   ?   ?   ?   R . n 
D 4 176 GLY 176 40   ?   ?   ?   R . n 
D 4 177 ASN 177 41   ?   ?   ?   R . n 
D 4 178 ALA 178 42   ?   ?   ?   R . n 
D 4 179 SER 179 43   ?   ?   ?   R . n 
D 4 180 GLU 180 44   ?   ?   ?   R . n 
D 4 181 ARG 181 45   ?   ?   ?   R . n 
D 4 182 VAL 182 46   ?   ?   ?   R . n 
D 4 183 LEU 183 47   ?   ?   ?   R . n 
D 4 184 ALA 184 48   ?   ?   ?   R . n 
D 4 185 ALA 185 49   ?   ?   ?   R . n 
D 4 186 PRO 186 50   ?   ?   ?   R . n 
D 4 187 SER 187 51   ?   ?   ?   R . n 
D 4 188 SER 188 52   ?   ?   ?   R . n 
D 4 189 GLU 189 53   ?   ?   ?   R . n 
D 4 190 LEU 190 54   ?   ?   ?   R . n 
D 4 191 ASP 191 55   ?   ?   ?   R . n 
D 4 192 VAL 192 56   56  VAL VAL R . n 
D 4 193 ASN 193 57   57  ASN ASN R . n 
D 4 194 THR 194 58   58  THR THR R . n 
D 4 195 ASP 195 59   59  ASP ASP R . n 
D 4 196 ILE 196 60   60  ILE ILE R . n 
D 4 197 TYR 197 61   61  TYR TYR R . n 
D 4 198 SER 198 62   62  SER SER R . n 
D 4 199 LYS 199 63   63  LYS LYS R . n 
D 4 200 VAL 200 64   64  VAL VAL R . n 
D 4 201 LEU 201 65   65  LEU LEU R . n 
D 4 202 VAL 202 66   66  VAL VAL R . n 
D 4 203 THR 203 67   67  THR THR R . n 
D 4 204 ALA 204 68   68  ALA ALA R . n 
D 4 205 VAL 205 69   69  VAL VAL R . n 
D 4 206 TYR 206 70   70  TYR TYR R . n 
D 4 207 LEU 207 71   71  LEU LEU R . n 
D 4 208 ALA 208 72   72  ALA ALA R . n 
D 4 209 LEU 209 73   73  LEU LEU R . n 
D 4 210 PHE 210 74   74  PHE PHE R . n 
D 4 211 VAL 211 75   75  VAL VAL R . n 
D 4 212 VAL 212 76   76  VAL VAL R . n 
D 4 213 GLY 213 77   77  GLY GLY R . n 
D 4 214 THR 214 78   78  THR THR R . n 
D 4 215 VAL 215 79   79  VAL VAL R . n 
D 4 216 GLY 216 80   80  GLY GLY R . n 
D 4 217 ASN 217 81   81  ASN ASN R . n 
D 4 218 THR 218 82   82  THR THR R . n 
D 4 219 VAL 219 83   83  VAL VAL R . n 
D 4 220 THR 220 84   84  THR THR R . n 
D 4 221 ALA 221 85   85  ALA ALA R . n 
D 4 222 PHE 222 86   86  PHE PHE R . n 
D 4 223 THR 223 87   87  THR THR R . n 
D 4 224 LEU 224 88   88  LEU LEU R . n 
D 4 225 ALA 225 89   89  ALA ALA R . n 
D 4 226 ARG 226 90   90  ARG ARG R . n 
D 4 227 LYS 227 91   91  LYS LYS R . n 
D 4 228 LYS 228 92   92  LYS LYS R . n 
D 4 229 SER 229 93   93  SER SER R . n 
D 4 230 LEU 230 94   94  LEU LEU R . n 
D 4 231 GLN 231 95   95  GLN GLN R . n 
D 4 232 SER 232 96   96  SER SER R . n 
D 4 233 LEU 233 97   97  LEU LEU R . n 
D 4 234 GLN 234 98   98  GLN GLN R . n 
D 4 235 SER 235 99   99  SER SER R . n 
D 4 236 THR 236 100  100 THR THR R . n 
D 4 237 VAL 237 101  101 VAL VAL R . n 
D 4 238 HIS 238 102  102 HIS HIS R . n 
D 4 239 TYR 239 103  103 TYR TYR R . n 
D 4 240 HIS 240 104  104 HIS HIS R . n 
D 4 241 LEU 241 105  105 LEU LEU R . n 
D 4 242 GLY 242 106  106 GLY GLY R . n 
D 4 243 SER 243 107  107 SER SER R . n 
D 4 244 LEU 244 108  108 LEU LEU R . n 
D 4 245 ALA 245 109  109 ALA ALA R . n 
D 4 246 LEU 246 110  110 LEU LEU R . n 
D 4 247 SER 247 111  111 SER SER R . n 
D 4 248 ASP 248 112  112 ASP ASP R . n 
D 4 249 LEU 249 113  113 LEU LEU R . n 
D 4 250 LEU 250 114  114 LEU LEU R . n 
D 4 251 THR 251 115  115 THR THR R . n 
D 4 252 LEU 252 116  116 LEU LEU R . n 
D 4 253 LEU 253 117  117 LEU LEU R . n 
D 4 254 LEU 254 118  118 LEU LEU R . n 
D 4 255 ALA 255 119  119 ALA ALA R . n 
D 4 256 MET 256 120  120 MET MET R . n 
D 4 257 PRO 257 121  121 PRO PRO R . n 
D 4 258 VAL 258 122  122 VAL VAL R . n 
D 4 259 GLU 259 123  123 GLU GLU R . n 
D 4 260 LEU 260 124  124 LEU LEU R . n 
D 4 261 TYR 261 125  125 TYR TYR R . n 
D 4 262 ASN 262 126  126 ASN ASN R . n 
D 4 263 PHE 263 127  127 PHE PHE R . n 
D 4 264 ILE 264 128  128 ILE ILE R . n 
D 4 265 TRP 265 129  129 TRP TRP R . n 
D 4 266 VAL 266 130  130 VAL VAL R . n 
D 4 267 HIS 267 131  131 HIS HIS R . n 
D 4 268 HIS 268 132  132 HIS HIS R . n 
D 4 269 PRO 269 133  133 PRO PRO R . n 
D 4 270 TRP 270 134  134 TRP TRP R . n 
D 4 271 ALA 271 135  135 ALA ALA R . n 
D 4 272 PHE 272 136  136 PHE PHE R . n 
D 4 273 GLY 273 137  137 GLY GLY R . n 
D 4 274 ASP 274 138  138 ASP ASP R . n 
D 4 275 ALA 275 139  139 ALA ALA R . n 
D 4 276 GLY 276 140  140 GLY GLY R . n 
D 4 277 CYS 277 141  141 CYS CYS R . n 
D 4 278 ARG 278 142  142 ARG ARG R . n 
D 4 279 GLY 279 143  143 GLY GLY R . n 
D 4 280 TYR 280 144  144 TYR TYR R . n 
D 4 281 TYR 281 145  145 TYR TYR R . n 
D 4 282 PHE 282 146  146 PHE PHE R . n 
D 4 283 LEU 283 147  147 LEU LEU R . n 
D 4 284 ARG 284 148  148 ARG ARG R . n 
D 4 285 ASP 285 149  149 ASP ASP R . n 
D 4 286 ALA 286 150  150 ALA ALA R . n 
D 4 287 CYS 287 151  151 CYS CYS R . n 
D 4 288 THR 288 152  152 THR THR R . n 
D 4 289 TYR 289 153  153 TYR TYR R . n 
D 4 290 ALA 290 154  154 ALA ALA R . n 
D 4 291 THR 291 155  155 THR THR R . n 
D 4 292 ALA 292 156  156 ALA ALA R . n 
D 4 293 LEU 293 157  157 LEU LEU R . n 
D 4 294 ASN 294 158  158 ASN ASN R . n 
D 4 295 VAL 295 159  159 VAL VAL R . n 
D 4 296 ALA 296 160  160 ALA ALA R . n 
D 4 297 SER 297 161  161 SER SER R . n 
D 4 298 LEU 298 162  162 LEU LEU R . n 
D 4 299 SER 299 163  163 SER SER R . n 
D 4 300 VAL 300 164  164 VAL VAL R . n 
D 4 301 GLU 301 165  165 GLU GLU R . n 
D 4 302 ARG 302 166  166 ARG ARG R . n 
D 4 303 TYR 303 167  167 TYR TYR R . n 
D 4 304 LEU 304 168  168 LEU LEU R . n 
D 4 305 ALA 305 169  169 ALA ALA R . n 
D 4 306 LEU 306 170  170 LEU LEU R . n 
D 4 307 CYS 307 171  171 CYS CYS R . n 
D 4 308 HIS 308 172  172 HIS HIS R . n 
D 4 309 PRO 309 173  173 PRO PRO R . n 
D 4 310 PHE 310 174  174 PHE PHE R . n 
D 4 311 LYS 311 175  175 LYS LYS R . n 
D 4 312 ALA 312 176  176 ALA ALA R . n 
D 4 313 LYS 313 177  177 LYS LYS R . n 
D 4 314 THR 314 178  178 THR THR R . n 
D 4 315 LEU 315 179  179 LEU LEU R . n 
D 4 316 MET 316 180  180 MET MET R . n 
D 4 317 SER 317 181  181 SER SER R . n 
D 4 318 ARG 318 182  182 ARG ARG R . n 
D 4 319 SER 319 183  183 SER SER R . n 
D 4 320 ARG 320 184  184 ARG ARG R . n 
D 4 321 THR 321 185  185 THR THR R . n 
D 4 322 LYS 322 186  186 LYS LYS R . n 
D 4 323 LYS 323 187  187 LYS LYS R . n 
D 4 324 PHE 324 188  188 PHE PHE R . n 
D 4 325 ILE 325 189  189 ILE ILE R . n 
D 4 326 SER 326 190  190 SER SER R . n 
D 4 327 ALA 327 191  191 ALA ALA R . n 
D 4 328 ILE 328 192  192 ILE ILE R . n 
D 4 329 TRP 329 193  193 TRP TRP R . n 
D 4 330 LEU 330 194  194 LEU LEU R . n 
D 4 331 ALA 331 195  195 ALA ALA R . n 
D 4 332 SER 332 196  196 SER SER R . n 
D 4 333 ALA 333 197  197 ALA ALA R . n 
D 4 334 LEU 334 198  198 LEU LEU R . n 
D 4 335 LEU 335 199  199 LEU LEU R . n 
D 4 336 ALA 336 200  200 ALA ALA R . n 
D 4 337 VAL 337 201  201 VAL VAL R . n 
D 4 338 PRO 338 202  202 PRO PRO R . n 
D 4 339 MET 339 203  203 MET MET R . n 
D 4 340 LEU 340 204  204 LEU LEU R . n 
D 4 341 PHE 341 205  205 PHE PHE R . n 
D 4 342 THR 342 206  206 THR THR R . n 
D 4 343 MET 343 207  207 MET MET R . n 
D 4 344 GLY 344 208  208 GLY GLY R . n 
D 4 345 GLU 345 209  209 GLU GLU R . n 
D 4 346 GLN 346 210  210 GLN GLN R . n 
D 4 347 ASN 347 211  211 ASN ASN R . n 
D 4 348 ARG 348 212  212 ARG ARG R . n 
D 4 349 SER 349 213  213 SER SER R . n 
D 4 350 ALA 350 214  214 ALA ALA R . n 
D 4 351 ASP 351 215  215 ASP ASP R . n 
D 4 352 GLY 352 216  216 GLY GLY R . n 
D 4 353 GLN 353 217  217 GLN GLN R . n 
D 4 354 HIS 354 218  218 HIS HIS R . n 
D 4 355 ALA 355 219  219 ALA ALA R . n 
D 4 356 GLY 356 220  220 GLY GLY R . n 
D 4 357 GLY 357 221  221 GLY GLY R . n 
D 4 358 LEU 358 222  222 LEU LEU R . n 
D 4 359 VAL 359 223  223 VAL VAL R . n 
D 4 360 CYS 360 224  224 CYS CYS R . n 
D 4 361 THR 361 225  225 THR THR R . n 
D 4 362 PRO 362 226  226 PRO PRO R . n 
D 4 363 THR 363 227  227 THR THR R . n 
D 4 364 ILE 364 228  228 ILE ILE R . n 
D 4 365 HIS 365 229  229 HIS HIS R . n 
D 4 366 THR 366 230  230 THR THR R . n 
D 4 367 ALA 367 231  231 ALA ALA R . n 
D 4 368 THR 368 232  232 THR THR R . n 
D 4 369 VAL 369 233  233 VAL VAL R . n 
D 4 370 LYS 370 234  234 LYS LYS R . n 
D 4 371 VAL 371 235  235 VAL VAL R . n 
D 4 372 VAL 372 236  236 VAL VAL R . n 
D 4 373 ILE 373 237  237 ILE ILE R . n 
D 4 374 GLN 374 238  238 GLN GLN R . n 
D 4 375 VAL 375 239  239 VAL VAL R . n 
D 4 376 ASN 376 240  240 ASN ASN R . n 
D 4 377 THR 377 241  241 THR THR R . n 
D 4 378 PHE 378 242  242 PHE PHE R . n 
D 4 379 MET 379 243  243 MET MET R . n 
D 4 380 SER 380 244  244 SER SER R . n 
D 4 381 PHE 381 245  245 PHE PHE R . n 
D 4 382 ILE 382 246  246 ILE ILE R . n 
D 4 383 PHE 383 247  247 PHE PHE R . n 
D 4 384 PRO 384 248  248 PRO PRO R . n 
D 4 385 MET 385 249  249 MET MET R . n 
D 4 386 VAL 386 250  250 VAL VAL R . n 
D 4 387 VAL 387 251  251 VAL VAL R . n 
D 4 388 ILE 388 252  252 ILE ILE R . n 
D 4 389 SER 389 253  253 SER SER R . n 
D 4 390 VAL 390 254  254 VAL VAL R . n 
D 4 391 LEU 391 255  255 LEU LEU R . n 
D 4 392 ASN 392 256  256 ASN ASN R . n 
D 4 393 THR 393 257  257 THR THR R . n 
D 4 394 ILE 394 258  258 ILE ILE R . n 
D 4 395 ILE 395 259  259 ILE ILE R . n 
D 4 396 ALA 396 260  260 ALA ALA R . n 
D 4 397 ASN 397 261  261 ASN ASN R . n 
D 4 398 LYS 398 262  262 LYS LYS R . n 
D 4 399 LEU 399 263  263 LEU LEU R . n 
D 4 400 THR 400 264  264 THR THR R . n 
D 4 401 VAL 401 265  265 VAL VAL R . n 
D 4 402 MET 402 266  266 MET MET R . n 
D 4 403 VAL 403 267  267 VAL VAL R . n 
D 4 404 ARG 404 268  ?   ?   ?   R . n 
D 4 405 GLN 405 269  ?   ?   ?   R . n 
D 4 406 ALA 406 270  ?   ?   ?   R . n 
D 4 407 ALA 407 271  ?   ?   ?   R . n 
D 4 408 GLU 408 272  ?   ?   ?   R . n 
D 4 409 GLN 409 273  ?   ?   ?   R . n 
D 4 410 GLY 410 274  ?   ?   ?   R . n 
D 4 411 GLN 411 275  ?   ?   ?   R . n 
D 4 412 VAL 412 276  ?   ?   ?   R . n 
D 4 413 CYS 413 277  ?   ?   ?   R . n 
D 4 414 THR 414 278  ?   ?   ?   R . n 
D 4 415 VAL 415 279  ?   ?   ?   R . n 
D 4 416 GLY 416 280  ?   ?   ?   R . n 
D 4 417 GLY 417 281  ?   ?   ?   R . n 
D 4 418 GLU 418 282  ?   ?   ?   R . n 
D 4 419 HIS 419 283  ?   ?   ?   R . n 
D 4 420 SER 420 284  ?   ?   ?   R . n 
D 4 421 THR 421 285  ?   ?   ?   R . n 
D 4 422 PHE 422 286  ?   ?   ?   R . n 
D 4 423 SER 423 287  ?   ?   ?   R . n 
D 4 424 MET 424 288  ?   ?   ?   R . n 
D 4 425 ALA 425 289  ?   ?   ?   R . n 
D 4 426 ILE 426 290  ?   ?   ?   R . n 
D 4 427 GLU 427 291  ?   ?   ?   R . n 
D 4 428 PRO 428 292  ?   ?   ?   R . n 
D 4 429 GLY 429 293  ?   ?   ?   R . n 
D 4 430 ARG 430 294  ?   ?   ?   R . n 
D 4 431 VAL 431 295  ?   ?   ?   R . n 
D 4 432 GLN 432 296  ?   ?   ?   R . n 
D 4 433 ALA 433 297  ?   ?   ?   R . n 
D 4 434 LEU 434 298  ?   ?   ?   R . n 
D 4 435 ARG 435 299  299 ARG ARG R . n 
D 4 436 HIS 436 300  300 HIS HIS R . n 
D 4 437 GLY 437 301  301 GLY GLY R . n 
D 4 438 VAL 438 302  302 VAL VAL R . n 
D 4 439 ARG 439 303  303 ARG ARG R . n 
D 4 440 VAL 440 304  304 VAL VAL R . n 
D 4 441 LEU 441 305  305 LEU LEU R . n 
D 4 442 ARG 442 306  306 ARG ARG R . n 
D 4 443 ALA 443 307  307 ALA ALA R . n 
D 4 444 VAL 444 308  308 VAL VAL R . n 
D 4 445 VAL 445 309  309 VAL VAL R . n 
D 4 446 ILE 446 310  310 ILE ILE R . n 
D 4 447 ALA 447 311  311 ALA ALA R . n 
D 4 448 PHE 448 312  312 PHE PHE R . n 
D 4 449 VAL 449 313  313 VAL ALA R . n 
D 4 450 VAL 450 314  314 VAL VAL R . n 
D 4 451 CYS 451 315  315 CYS CYS R . n 
D 4 452 TRP 452 316  316 TRP TRP R . n 
D 4 453 LEU 453 317  317 LEU LEU R . n 
D 4 454 PRO 454 318  318 PRO PRO R . n 
D 4 455 TYR 455 319  319 TYR TYR R . n 
D 4 456 HIS 456 320  320 HIS HIS R . n 
D 4 457 VAL 457 321  321 VAL VAL R . n 
D 4 458 ARG 458 322  322 ARG ARG R . n 
D 4 459 ARG 459 323  323 ARG ARG R . n 
D 4 460 LEU 460 324  324 LEU LEU R . n 
D 4 461 MET 461 325  325 MET MET R . n 
D 4 462 PHE 462 326  326 PHE PHE R . n 
D 4 463 CYS 463 327  327 CYS CYS R . n 
D 4 464 TYR 464 328  328 TYR TYR R . n 
D 4 465 ILE 465 329  329 ILE ILE R . n 
D 4 466 SER 466 330  330 SER SER R . n 
D 4 467 ASP 467 331  331 ASP ASP R . n 
D 4 468 GLU 468 332  332 GLU GLU R . n 
D 4 469 GLN 469 333  333 GLN GLN R . n 
D 4 470 TRP 470 334  334 TRP TRP R . n 
D 4 471 THR 471 335  335 THR THR R . n 
D 4 472 PRO 472 336  336 PRO PRO R . n 
D 4 473 PHE 473 337  337 PHE PHE R . n 
D 4 474 LEU 474 338  338 LEU LEU R . n 
D 4 475 TYR 475 339  339 TYR TYR R . n 
D 4 476 ASP 476 340  340 ASP ASP R . n 
D 4 477 PHE 477 341  341 PHE PHE R . n 
D 4 478 TYR 478 342  342 TYR TYR R . n 
D 4 479 HIS 479 343  343 HIS HIS R . n 
D 4 480 TYR 480 344  344 TYR TYR R . n 
D 4 481 PHE 481 345  345 PHE PHE R . n 
D 4 482 TYR 482 346  346 TYR TYR R . n 
D 4 483 MET 483 347  347 MET MET R . n 
D 4 484 VAL 484 348  348 VAL VAL R . n 
D 4 485 THR 485 349  349 THR THR R . n 
D 4 486 ASN 486 350  350 ASN ASN R . n 
D 4 487 ALA 487 351  351 ALA ALA R . n 
D 4 488 LEU 488 352  352 LEU LEU R . n 
D 4 489 PHE 489 353  353 PHE PHE R . n 
D 4 490 TYR 490 354  354 TYR TYR R . n 
D 4 491 VAL 491 355  355 VAL VAL R . n 
D 4 492 SER 492 356  356 SER SER R . n 
D 4 493 SER 493 357  357 SER SER R . n 
D 4 494 THR 494 358  358 THR THR R . n 
D 4 495 ILE 495 359  359 ILE ILE R . n 
D 4 496 ASN 496 360  360 ASN ASN R . n 
D 4 497 PRO 497 361  361 PRO PRO R . n 
D 4 498 ILE 498 362  362 ILE ILE R . n 
D 4 499 LEU 499 363  363 LEU LEU R . n 
D 4 500 TYR 500 364  364 TYR TYR R . n 
D 4 501 ASN 501 365  365 ASN ASN R . n 
D 4 502 LEU 502 366  366 LEU LEU R . n 
D 4 503 VAL 503 367  367 VAL VAL R . n 
D 4 504 SER 504 368  368 SER SER R . n 
D 4 505 ALA 505 369  369 ALA ALA R . n 
D 4 506 ASN 506 370  370 ASN ASN R . n 
D 4 507 PHE 507 371  371 PHE PHE R . n 
D 4 508 ARG 508 372  372 ARG ARG R . n 
D 4 509 HIS 509 373  373 HIS HIS R . n 
D 4 510 ILE 510 374  374 ILE ILE R . n 
D 4 511 PHE 511 375  375 PHE PHE R . n 
D 4 512 ILE 512 376  376 ILE ILE R . n 
D 4 513 ALA 513 377  377 ALA ALA R . n 
D 4 514 THR 514 378  378 THR THR R . n 
D 4 515 LEU 515 379  379 LEU LEU R . n 
D 4 516 ALA 516 380  380 ALA ALA R . n 
D 4 517 CYS 517 380  ?   ?   ?   R A n 
D 4 518 LEU 518 380  ?   ?   ?   R B n 
D 4 519 CYS 519 380  ?   ?   ?   R C n 
D 4 520 PRO 520 380  ?   ?   ?   R D n 
D 4 521 VAL 521 380  ?   ?   ?   R E n 
D 4 522 TRP 522 380  ?   ?   ?   R F n 
D 4 523 ARG 523 380  ?   ?   ?   R G n 
D 4 524 ARG 524 380  ?   ?   ?   R H n 
D 4 525 ARG 525 380  ?   ?   ?   R I n 
D 4 526 ARG 526 380  ?   ?   ?   R J n 
D 4 527 LYS 527 380  ?   ?   ?   R K n 
D 4 528 ARG 528 380  ?   ?   ?   R L n 
D 4 529 PRO 529 380  ?   ?   ?   R M n 
D 4 530 CYS 530 380  ?   ?   ?   R N n 
D 4 531 PHE 531 380  ?   ?   ?   R O n 
D 4 532 ASN 532 380  ?   ?   ?   R P n 
D 4 533 ALA 533 380  ?   ?   ?   R Q n 
D 4 534 PHE 534 380  ?   ?   ?   R R n 
D 4 535 SER 535 380  ?   ?   ?   R S n 
D 4 536 ARG 536 380  ?   ?   ?   R T n 
D 4 537 LYS 537 380  ?   ?   ?   R U n 
D 4 538 CYS 538 380  ?   ?   ?   R V n 
D 4 539 ASP 539 380  ?   ?   ?   R W n 
D 4 540 SEP 540 380  ?   ?   ?   R X n 
D 4 541 VAL 541 380  ?   ?   ?   R Y n 
D 4 542 SEP 542 380  ?   ?   ?   R Z n 
D 4 543 SEP 543 381  ?   ?   ?   R A n 
D 4 544 ASN 544 405  405 ASN ASN R . n 
D 4 545 HIS 545 406  406 HIS HIS R . n 
D 4 546 TPO 546 407  407 TPO TPO R . n 
D 4 547 LEU 547 408  408 LEU LEU R . n 
D 4 548 SEP 548 409  409 SEP SEP R . n 
D 4 549 SEP 549 410  410 SEP SEP R . n 
D 4 550 ASN 550 411  411 ASN ASN R . n 
D 4 551 ALA 551 412  412 ALA ALA R . n 
D 4 552 THR 552 413  ?   ?   ?   R . n 
D 4 553 ARG 553 414  ?   ?   ?   R . n 
D 4 554 GLU 554 415  ?   ?   ?   R . n 
D 4 555 THR 555 416  ?   ?   ?   R . n 
D 4 556 LEU 556 417  ?   ?   ?   R . n 
D 4 557 TYR 557 418  ?   ?   ?   R . n 
E 5 1   ARG 1   8    8   ARG ARG L . n 
E 5 2   ARG 2   9    9   ARG ARG L . n 
E 5 3   PRO 3   10   10  PRO PRO L . n 
E 5 4   TYR 4   11   11  TYR TYR L . n 
E 5 5   ILE 5   12   12  ILE ILE L . n 
E 5 6   LEU 6   13   13  LEU LEU L . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 SEP ? ? SEP ? ? 'SUBJECT OF INVESTIGATION' ? 
2 SRW ? ? SRW ? ? 'SUBJECT OF INVESTIGATION' ? 
3 TPO ? ? TPO ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
F 6 PIO 1 501 501 PIO PIO R . 
G 7 SRW 1 502 504 SRW SRW R . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 B ASP 31  ? CG  ? A ASP 52  CG  
2   1 Y 1 B ASP 31  ? OD1 ? A ASP 52  OD1 
3   1 Y 1 B ASP 31  ? OD2 ? A ASP 52  OD2 
4   1 Y 1 B ASP 37  ? CG  ? A ASP 58  CG  
5   1 Y 1 B ASP 37  ? OD1 ? A ASP 58  OD1 
6   1 Y 1 B ASP 37  ? OD2 ? A ASP 58  OD2 
7   1 Y 1 B GLU 45  ? CG  ? A GLU 66  CG  
8   1 Y 1 B GLU 45  ? CD  ? A GLU 66  CD  
9   1 Y 1 B GLU 45  ? OE1 ? A GLU 66  OE1 
10  1 Y 1 B GLU 45  ? OE2 ? A GLU 66  OE2 
11  1 Y 1 B GLU 49  ? CG  ? A GLU 70  CG  
12  1 Y 1 B GLU 49  ? CD  ? A GLU 70  CD  
13  1 Y 1 B GLU 49  ? OE1 ? A GLU 70  OE1 
14  1 Y 1 B GLU 49  ? OE2 ? A GLU 70  OE2 
15  1 Y 1 B ARG 64  ? CG  ? A ARG 85  CG  
16  1 Y 1 B ARG 64  ? CD  ? A ARG 85  CD  
17  1 Y 1 B ARG 64  ? NE  ? A ARG 85  NE  
18  1 Y 1 B ARG 64  ? CZ  ? A ARG 85  CZ  
19  1 Y 1 B ARG 64  ? NH1 ? A ARG 85  NH1 
20  1 Y 1 B ARG 64  ? NH2 ? A ARG 85  NH2 
21  1 Y 1 B GLU 65  ? CG  ? A GLU 86  CG  
22  1 Y 1 B GLU 65  ? CD  ? A GLU 86  CD  
23  1 Y 1 B GLU 65  ? OE1 ? A GLU 86  OE1 
24  1 Y 1 B GLU 65  ? OE2 ? A GLU 86  OE2 
25  1 Y 1 B ASP 66  ? CG  ? A ASP 87  CG  
26  1 Y 1 B ASP 66  ? OD1 ? A ASP 87  OD1 
27  1 Y 1 B ASP 66  ? OD2 ? A ASP 87  OD2 
28  1 Y 1 B LEU 67  ? CG  ? A LEU 88  CG  
29  1 Y 1 B LEU 67  ? CD1 ? A LEU 88  CD1 
30  1 Y 1 B LEU 67  ? CD2 ? A LEU 88  CD2 
31  1 Y 1 B ASP 68  ? CG  ? A ASP 89  CG  
32  1 Y 1 B ASP 68  ? OD1 ? A ASP 89  OD1 
33  1 Y 1 B ASP 68  ? OD2 ? A ASP 89  OD2 
34  1 Y 1 B VAL 69  ? CG1 ? A VAL 90  CG1 
35  1 Y 1 B VAL 69  ? CG2 ? A VAL 90  CG2 
36  1 Y 1 B LEU 70  ? CG  ? A LEU 91  CG  
37  1 Y 1 B LEU 70  ? CD1 ? A LEU 91  CD1 
38  1 Y 1 B LEU 70  ? CD2 ? A LEU 91  CD2 
39  1 Y 1 B LEU 72  ? CG  ? A LEU 93  CG  
40  1 Y 1 B LEU 72  ? CD1 ? A LEU 93  CD1 
41  1 Y 1 B LEU 72  ? CD2 ? A LEU 93  CD2 
42  1 Y 1 B THR 73  ? OG1 ? A THR 94  OG1 
43  1 Y 1 B THR 73  ? CG2 ? A THR 94  CG2 
44  1 Y 1 B PHE 74  ? CG  ? A PHE 95  CG  
45  1 Y 1 B PHE 74  ? CD1 ? A PHE 95  CD1 
46  1 Y 1 B PHE 74  ? CD2 ? A PHE 95  CD2 
47  1 Y 1 B PHE 74  ? CE1 ? A PHE 95  CE1 
48  1 Y 1 B PHE 74  ? CE2 ? A PHE 95  CE2 
49  1 Y 1 B PHE 74  ? CZ  ? A PHE 95  CZ  
50  1 Y 1 B GLU 91  ? CG  ? A GLU 112 CG  
51  1 Y 1 B GLU 91  ? CD  ? A GLU 112 CD  
52  1 Y 1 B GLU 91  ? OE1 ? A GLU 112 OE1 
53  1 Y 1 B GLU 91  ? OE2 ? A GLU 112 OE2 
54  1 Y 1 B ASP 92  ? CG  ? A ASP 113 CG  
55  1 Y 1 B ASP 92  ? OD1 ? A ASP 113 OD1 
56  1 Y 1 B ASP 92  ? OD2 ? A ASP 113 OD2 
57  1 Y 1 B LYS 93  ? CG  ? A LYS 114 CG  
58  1 Y 1 B LYS 93  ? CD  ? A LYS 114 CD  
59  1 Y 1 B LYS 93  ? CE  ? A LYS 114 CE  
60  1 Y 1 B LYS 93  ? NZ  ? A LYS 114 NZ  
61  1 Y 1 B ARG 98  ? CG  ? A ARG 119 CG  
62  1 Y 1 B ARG 98  ? CD  ? A ARG 119 CD  
63  1 Y 1 B ARG 98  ? NE  ? A ARG 119 NE  
64  1 Y 1 B ARG 98  ? CZ  ? A ARG 119 CZ  
65  1 Y 1 B ARG 98  ? NH1 ? A ARG 119 NH1 
66  1 Y 1 B ARG 98  ? NH2 ? A ARG 119 NH2 
67  1 Y 1 B LYS 105 ? CG  ? A LYS 126 CG  
68  1 Y 1 B LYS 105 ? CD  ? A LYS 126 CD  
69  1 Y 1 B LYS 105 ? CE  ? A LYS 126 CE  
70  1 Y 1 B LYS 105 ? NZ  ? A LYS 126 NZ  
71  1 Y 1 B GLU 109 ? CG  ? A GLU 130 CG  
72  1 Y 1 B GLU 109 ? CD  ? A GLU 130 CD  
73  1 Y 1 B GLU 109 ? OE1 ? A GLU 130 OE1 
74  1 Y 1 B GLU 109 ? OE2 ? A GLU 130 OE2 
75  1 Y 1 B GLU 117 ? CG  ? A GLU 138 CG  
76  1 Y 1 B GLU 117 ? CD  ? A GLU 138 CD  
77  1 Y 1 B GLU 117 ? OE1 ? A GLU 138 OE1 
78  1 Y 1 B GLU 117 ? OE2 ? A GLU 138 OE2 
79  1 Y 1 B GLU 133 ? CG  ? A GLU 154 CG  
80  1 Y 1 B GLU 133 ? CD  ? A GLU 154 CD  
81  1 Y 1 B GLU 133 ? OE1 ? A GLU 154 OE1 
82  1 Y 1 B GLU 133 ? OE2 ? A GLU 154 OE2 
83  1 Y 1 B ASP 134 ? CG  ? A ASP 155 CG  
84  1 Y 1 B ASP 134 ? OD1 ? A ASP 155 OD1 
85  1 Y 1 B ASP 134 ? OD2 ? A ASP 155 OD2 
86  1 Y 1 B THR 135 ? OG1 ? A THR 156 OG1 
87  1 Y 1 B THR 135 ? CG2 ? A THR 156 CG2 
88  1 Y 1 B LYS 137 ? CG  ? A LYS 158 CG  
89  1 Y 1 B LYS 137 ? CD  ? A LYS 158 CD  
90  1 Y 1 B LYS 137 ? CE  ? A LYS 158 CE  
91  1 Y 1 B LYS 137 ? NZ  ? A LYS 158 NZ  
92  1 Y 1 B GLU 151 ? CG  ? A GLU 172 CG  
93  1 Y 1 B GLU 151 ? CD  ? A GLU 172 CD  
94  1 Y 1 B GLU 151 ? OE1 ? A GLU 172 OE1 
95  1 Y 1 B GLU 151 ? OE2 ? A GLU 172 OE2 
96  1 Y 1 B GLU 154 ? CG  ? A GLU 175 CG  
97  1 Y 1 B GLU 154 ? CD  ? A GLU 175 CD  
98  1 Y 1 B GLU 154 ? OE1 ? A GLU 175 OE1 
99  1 Y 1 B GLU 154 ? OE2 ? A GLU 175 OE2 
100 1 Y 1 B GLU 155 ? CG  ? A GLU 176 CG  
101 1 Y 1 B GLU 155 ? CD  ? A GLU 176 CD  
102 1 Y 1 B GLU 155 ? OE1 ? A GLU 176 OE1 
103 1 Y 1 B GLU 155 ? OE2 ? A GLU 176 OE2 
104 1 Y 1 B GLU 175 ? CG  ? A GLU 196 CG  
105 1 Y 1 B GLU 175 ? CD  ? A GLU 196 CD  
106 1 Y 1 B GLU 175 ? OE1 ? A GLU 196 OE1 
107 1 Y 1 B GLU 175 ? OE2 ? A GLU 196 OE2 
108 1 Y 1 B ARG 176 ? CG  ? A ARG 197 CG  
109 1 Y 1 B ARG 176 ? CD  ? A ARG 197 CD  
110 1 Y 1 B ARG 176 ? NE  ? A ARG 197 NE  
111 1 Y 1 B ARG 176 ? CZ  ? A ARG 197 CZ  
112 1 Y 1 B ARG 176 ? NH1 ? A ARG 197 NH1 
113 1 Y 1 B ARG 176 ? NH2 ? A ARG 197 NH2 
114 1 Y 1 B GLN 188 ? CG  ? A GLN 209 CG  
115 1 Y 1 B GLN 188 ? CD  ? A GLN 209 CD  
116 1 Y 1 B GLN 188 ? OE1 ? A GLN 209 OE1 
117 1 Y 1 B GLN 188 ? NE2 ? A GLN 209 NE2 
118 1 Y 1 B LEU 190 ? CG  ? A LEU 211 CG  
119 1 Y 1 B LEU 190 ? CD1 ? A LEU 211 CD1 
120 1 Y 1 B LEU 190 ? CD2 ? A LEU 211 CD2 
121 1 Y 1 B MET 191 ? CG  ? A MET 212 CG  
122 1 Y 1 B MET 191 ? SD  ? A MET 212 SD  
123 1 Y 1 B MET 191 ? CE  ? A MET 212 CE  
124 1 Y 1 B SER 192 ? OG  ? A SER 213 OG  
125 1 Y 1 B ASP 193 ? CG  ? A ASP 214 CG  
126 1 Y 1 B ASP 193 ? OD1 ? A ASP 214 OD1 
127 1 Y 1 B ASP 193 ? OD2 ? A ASP 214 OD2 
128 1 Y 1 B LYS 194 ? CG  ? A LYS 215 CG  
129 1 Y 1 B LYS 194 ? CD  ? A LYS 215 CD  
130 1 Y 1 B LYS 194 ? CE  ? A LYS 215 CE  
131 1 Y 1 B LYS 194 ? NZ  ? A LYS 215 NZ  
132 1 Y 1 B ASN 221 ? CG  ? A ASN 242 CG  
133 1 Y 1 B ASN 221 ? OD1 ? A ASN 242 OD1 
134 1 Y 1 B ASN 221 ? ND2 ? A ASN 242 ND2 
135 1 Y 1 B ASN 222 ? CG  ? A ASN 243 CG  
136 1 Y 1 B ASN 222 ? OD1 ? A ASN 243 OD1 
137 1 Y 1 B ASN 222 ? ND2 ? A ASN 243 ND2 
138 1 Y 1 B THR 223 ? OG1 ? A THR 244 OG1 
139 1 Y 1 B THR 223 ? CG2 ? A THR 244 CG2 
140 1 Y 1 B ASN 224 ? CG  ? A ASN 245 CG  
141 1 Y 1 B ASN 224 ? OD1 ? A ASN 245 OD1 
142 1 Y 1 B ASN 224 ? ND2 ? A ASN 245 ND2 
143 1 Y 1 B LYS 225 ? CG  ? A LYS 246 CG  
144 1 Y 1 B LYS 225 ? CD  ? A LYS 246 CD  
145 1 Y 1 B LYS 225 ? CE  ? A LYS 246 CE  
146 1 Y 1 B LYS 225 ? NZ  ? A LYS 246 NZ  
147 1 Y 1 B ASN 244 ? CG  ? A ASN 265 CG  
148 1 Y 1 B ASN 244 ? OD1 ? A ASN 265 OD1 
149 1 Y 1 B ASN 244 ? ND2 ? A ASN 265 ND2 
150 1 Y 1 B ASP 258 ? CG  ? A ASP 279 CG  
151 1 Y 1 B ASP 258 ? OD1 ? A ASP 279 OD1 
152 1 Y 1 B ASP 258 ? OD2 ? A ASP 279 OD2 
153 1 Y 1 B ASP 259 ? CG  ? A ASP 280 CG  
154 1 Y 1 B ASP 259 ? OD1 ? A ASP 280 OD1 
155 1 Y 1 B ASP 259 ? OD2 ? A ASP 280 OD2 
156 1 Y 1 B ARG 306 ? CG  ? A ARG 327 CG  
157 1 Y 1 B ARG 306 ? CD  ? A ARG 327 CD  
158 1 Y 1 B ARG 306 ? NE  ? A ARG 327 NE  
159 1 Y 1 B ARG 306 ? CZ  ? A ARG 327 CZ  
160 1 Y 1 B ARG 306 ? NH1 ? A ARG 327 NH1 
161 1 Y 1 B ARG 306 ? NH2 ? A ARG 327 NH2 
162 1 Y 1 B GLU 307 ? CG  ? A GLU 328 CG  
163 1 Y 1 B GLU 307 ? CD  ? A GLU 328 CD  
164 1 Y 1 B GLU 307 ? OE1 ? A GLU 328 OE1 
165 1 Y 1 B GLU 307 ? OE2 ? A GLU 328 OE2 
166 1 Y 1 B ASN 310 ? CG  ? A ASN 331 CG  
167 1 Y 1 B ASN 310 ? OD1 ? A ASN 331 OD1 
168 1 Y 1 B ASN 310 ? ND2 ? A ASN 331 ND2 
169 1 Y 1 B ARG 311 ? CG  ? A ARG 332 CG  
170 1 Y 1 B ARG 311 ? CD  ? A ARG 332 CD  
171 1 Y 1 B ARG 311 ? NE  ? A ARG 332 NE  
172 1 Y 1 B ARG 311 ? CZ  ? A ARG 332 CZ  
173 1 Y 1 B ARG 311 ? NH1 ? A ARG 332 NH1 
174 1 Y 1 B ARG 311 ? NH2 ? A ARG 332 NH2 
175 1 Y 1 B LEU 314 ? CG  ? A LEU 335 CG  
176 1 Y 1 B LEU 314 ? CD1 ? A LEU 335 CD1 
177 1 Y 1 B LEU 314 ? CD2 ? A LEU 335 CD2 
178 1 Y 1 B ARG 330 ? CG  ? A ARG 351 CG  
179 1 Y 1 B ARG 330 ? CD  ? A ARG 351 CD  
180 1 Y 1 B ARG 330 ? NE  ? A ARG 351 NE  
181 1 Y 1 B ARG 330 ? CZ  ? A ARG 351 CZ  
182 1 Y 1 B ARG 330 ? NH1 ? A ARG 351 NH1 
183 1 Y 1 B ARG 330 ? NH2 ? A ARG 351 NH2 
184 1 Y 1 B LEU 333 ? CG  ? A LEU 354 CG  
185 1 Y 1 B LEU 333 ? CD1 ? A LEU 354 CD1 
186 1 Y 1 B LEU 333 ? CD2 ? A LEU 354 CD2 
187 1 Y 1 B LEU 334 ? CG  ? A LEU 355 CG  
188 1 Y 1 B LEU 334 ? CD1 ? A LEU 355 CD1 
189 1 Y 1 B LEU 334 ? CD2 ? A LEU 355 CD2 
190 1 Y 1 B ASP 336 ? CG  ? A ASP 357 CG  
191 1 Y 1 B ASP 336 ? OD1 ? A ASP 357 OD1 
192 1 Y 1 B ASP 336 ? OD2 ? A ASP 357 OD2 
193 1 Y 1 B LEU 337 ? CG  ? A LEU 358 CG  
194 1 Y 1 B LEU 337 ? CD1 ? A LEU 358 CD1 
195 1 Y 1 B LEU 337 ? CD2 ? A LEU 358 CD2 
196 1 Y 1 B LYS 356 ? CG  ? A LYS 377 CG  
197 1 Y 1 B LYS 356 ? CD  ? A LYS 377 CD  
198 1 Y 1 B LYS 356 ? CE  ? A LYS 377 CE  
199 1 Y 1 B LYS 356 ? NZ  ? A LYS 377 NZ  
200 1 Y 1 B GLU 357 ? CG  ? A GLU 378 CG  
201 1 Y 1 B GLU 357 ? CD  ? A GLU 378 CD  
202 1 Y 1 B GLU 357 ? OE1 ? A GLU 378 OE1 
203 1 Y 1 B GLU 357 ? OE2 ? A GLU 378 OE2 
204 1 Y 1 B GLU 358 ? CG  ? A GLU 379 CG  
205 1 Y 1 B GLU 358 ? CD  ? A GLU 379 CD  
206 1 Y 1 B GLU 358 ? OE1 ? A GLU 379 OE1 
207 1 Y 1 B GLU 358 ? OE2 ? A GLU 379 OE2 
208 1 Y 1 B GLU 363 ? CG  ? A GLU 384 CG  
209 1 Y 1 B GLU 363 ? CD  ? A GLU 384 CD  
210 1 Y 1 B GLU 363 ? OE1 ? A GLU 384 OE1 
211 1 Y 1 B GLU 363 ? OE2 ? A GLU 384 OE2 
212 1 Y 1 D GLU 24  ? CG  ? B GLU 24  CG  
213 1 Y 1 D GLU 24  ? CD  ? B GLU 24  CD  
214 1 Y 1 D GLU 24  ? OE1 ? B GLU 24  OE1 
215 1 Y 1 D GLU 24  ? OE2 ? B GLU 24  OE2 
216 1 Y 1 D ASP 85  ? CG  ? B ASP 85  CG  
217 1 Y 1 D ASP 85  ? OD1 ? B ASP 85  OD1 
218 1 Y 1 D ASP 85  ? OD2 ? B ASP 85  OD2 
219 1 Y 1 D LYS 99  ? CG  ? B LYS 99  CG  
220 1 Y 1 D LYS 99  ? CD  ? B LYS 99  CD  
221 1 Y 1 D LYS 99  ? CE  ? B LYS 99  CE  
222 1 Y 1 D LYS 99  ? NZ  ? B LYS 99  NZ  
223 1 Y 1 D CYS 170 ? SG  ? B CYS 170 SG  
224 1 Y 1 D ASN 185 ? CG  ? B ASN 185 CG  
225 1 Y 1 D ASN 185 ? OD1 ? B ASN 185 OD1 
226 1 Y 1 D ASN 185 ? ND2 ? B ASN 185 ND2 
227 1 Y 1 D CYS 226 ? SG  ? B CYS 226 SG  
228 1 Y 1 D ASN 229 ? CG  ? B ASN 229 CG  
229 1 Y 1 D ASN 229 ? OD1 ? B ASN 229 OD1 
230 1 Y 1 D ASN 229 ? ND2 ? B ASN 229 ND2 
231 1 Y 1 D LYS 231 ? CG  ? B LYS 231 CG  
232 1 Y 1 D LYS 231 ? CD  ? B LYS 231 CD  
233 1 Y 1 D LYS 231 ? CE  ? B LYS 231 CE  
234 1 Y 1 D LYS 231 ? NZ  ? B LYS 231 NZ  
235 1 Y 1 D ASN 234 ? CG  ? B ASN 234 CG  
236 1 Y 1 D ASN 234 ? OD1 ? B ASN 234 OD1 
237 1 Y 1 D ASN 234 ? ND2 ? B ASN 234 ND2 
238 1 Y 1 D LYS 236 ? CG  ? B LYS 236 CG  
239 1 Y 1 D LYS 236 ? CD  ? B LYS 236 CD  
240 1 Y 1 D LYS 236 ? CE  ? B LYS 236 CE  
241 1 Y 1 D LYS 236 ? NZ  ? B LYS 236 NZ  
242 1 Y 1 Q GLN 24  ? CG  ? C GLN 24  CG  
243 1 Y 1 Q GLN 24  ? CD  ? C GLN 24  CD  
244 1 Y 1 Q GLN 24  ? OE1 ? C GLN 24  OE1 
245 1 Y 1 Q GLN 24  ? NE2 ? C GLN 24  NE2 
246 1 Y 1 Q SER 77  ? OG  ? C SER 77  OG  
247 1 Y 1 Q LYS 128 ? CG  ? C LYS 128 CG  
248 1 Y 1 Q LYS 128 ? CD  ? C LYS 128 CD  
249 1 Y 1 Q LYS 128 ? CE  ? C LYS 128 CE  
250 1 Y 1 Q LYS 128 ? NZ  ? C LYS 128 NZ  
251 1 Y 1 Q ARG 129 ? CG  ? C ARG 129 CG  
252 1 Y 1 Q ARG 129 ? CD  ? C ARG 129 CD  
253 1 Y 1 Q ARG 129 ? NE  ? C ARG 129 NE  
254 1 Y 1 Q ARG 129 ? CZ  ? C ARG 129 CZ  
255 1 Y 1 Q ARG 129 ? NH1 ? C ARG 129 NH1 
256 1 Y 1 Q ARG 129 ? NH2 ? C ARG 129 NH2 
257 1 Y 1 Q LYS 166 ? CB  ? C LYS 166 CB  
258 1 Y 1 Q LYS 166 ? CG  ? C LYS 166 CG  
259 1 Y 1 Q LYS 166 ? CD  ? C LYS 166 CD  
260 1 Y 1 Q LYS 166 ? CE  ? C LYS 166 CE  
261 1 Y 1 Q LYS 166 ? NZ  ? C LYS 166 NZ  
262 1 Y 1 Q GLN 168 ? CG  ? C GLN 168 CG  
263 1 Y 1 Q GLN 168 ? CD  ? C GLN 168 CD  
264 1 Y 1 Q GLN 168 ? OE1 ? C GLN 168 OE1 
265 1 Y 1 Q GLN 168 ? NE2 ? C GLN 168 NE2 
266 1 Y 1 Q GLN 176 ? CG  ? C GLN 176 CG  
267 1 Y 1 Q GLN 176 ? CD  ? C GLN 176 CD  
268 1 Y 1 Q GLN 176 ? OE1 ? C GLN 176 OE1 
269 1 Y 1 Q GLN 176 ? NE2 ? C GLN 176 NE2 
270 1 Y 1 Q ASN 179 ? CG  ? C ASN 179 CG  
271 1 Y 1 Q ASN 179 ? OD1 ? C ASN 179 OD1 
272 1 Y 1 Q ASN 179 ? ND2 ? C ASN 179 ND2 
273 1 Y 1 Q GLU 182 ? CG  ? C GLU 182 CG  
274 1 Y 1 Q GLU 182 ? CD  ? C GLU 182 CD  
275 1 Y 1 Q GLU 182 ? OE1 ? C GLU 182 OE1 
276 1 Y 1 Q GLU 182 ? OE2 ? C GLU 182 OE2 
277 1 Y 1 Q LYS 190 ? CG  ? C LYS 190 CG  
278 1 Y 1 Q LYS 190 ? CD  ? C LYS 190 CD  
279 1 Y 1 Q LYS 190 ? CE  ? C LYS 190 CE  
280 1 Y 1 Q LYS 190 ? NZ  ? C LYS 190 NZ  
281 1 Y 1 Q SER 197 ? OG  ? C SER 197 OG  
282 1 Y 1 Q LYS 204 ? CG  ? C LYS 204 CG  
283 1 Y 1 Q LYS 204 ? CD  ? C LYS 204 CD  
284 1 Y 1 Q LYS 204 ? CE  ? C LYS 204 CE  
285 1 Y 1 Q LYS 204 ? NZ  ? C LYS 204 NZ  
286 1 Y 1 Q GLN 220 ? CG  ? C GLN 220 CG  
287 1 Y 1 Q GLN 220 ? CD  ? C GLN 220 CD  
288 1 Y 1 Q GLN 220 ? OE1 ? C GLN 220 OE1 
289 1 Y 1 Q GLN 220 ? NE2 ? C GLN 220 NE2 
290 1 Y 1 Q PHE 230 ? CG  ? C PHE 230 CG  
291 1 Y 1 Q PHE 230 ? CD1 ? C PHE 230 CD1 
292 1 Y 1 Q PHE 230 ? CD2 ? C PHE 230 CD2 
293 1 Y 1 Q PHE 230 ? CE1 ? C PHE 230 CE1 
294 1 Y 1 Q PHE 230 ? CE2 ? C PHE 230 CE2 
295 1 Y 1 Q PHE 230 ? CZ  ? C PHE 230 CZ  
296 1 Y 1 R VAL 56  ? CG1 ? D VAL 192 CG1 
297 1 Y 1 R VAL 56  ? CG2 ? D VAL 192 CG2 
298 1 Y 1 R ASN 57  ? CG  ? D ASN 193 CG  
299 1 Y 1 R ASN 57  ? OD1 ? D ASN 193 OD1 
300 1 Y 1 R ASN 57  ? ND2 ? D ASN 193 ND2 
301 1 Y 1 R THR 58  ? OG1 ? D THR 194 OG1 
302 1 Y 1 R THR 58  ? CG2 ? D THR 194 CG2 
303 1 Y 1 R ASP 59  ? CG  ? D ASP 195 CG  
304 1 Y 1 R ASP 59  ? OD1 ? D ASP 195 OD1 
305 1 Y 1 R ASP 59  ? OD2 ? D ASP 195 OD2 
306 1 Y 1 R ILE 60  ? CG1 ? D ILE 196 CG1 
307 1 Y 1 R ILE 60  ? CG2 ? D ILE 196 CG2 
308 1 Y 1 R ILE 60  ? CD1 ? D ILE 196 CD1 
309 1 Y 1 R TYR 61  ? CG  ? D TYR 197 CG  
310 1 Y 1 R TYR 61  ? CD1 ? D TYR 197 CD1 
311 1 Y 1 R TYR 61  ? CD2 ? D TYR 197 CD2 
312 1 Y 1 R TYR 61  ? CE1 ? D TYR 197 CE1 
313 1 Y 1 R TYR 61  ? CE2 ? D TYR 197 CE2 
314 1 Y 1 R TYR 61  ? CZ  ? D TYR 197 CZ  
315 1 Y 1 R TYR 61  ? OH  ? D TYR 197 OH  
316 1 Y 1 R SER 62  ? OG  ? D SER 198 OG  
317 1 Y 1 R LYS 63  ? CG  ? D LYS 199 CG  
318 1 Y 1 R LYS 63  ? CD  ? D LYS 199 CD  
319 1 Y 1 R LYS 63  ? CE  ? D LYS 199 CE  
320 1 Y 1 R LYS 63  ? NZ  ? D LYS 199 NZ  
321 1 Y 1 R VAL 64  ? CG1 ? D VAL 200 CG1 
322 1 Y 1 R VAL 64  ? CG2 ? D VAL 200 CG2 
323 1 Y 1 R LEU 65  ? CG  ? D LEU 201 CG  
324 1 Y 1 R LEU 65  ? CD1 ? D LEU 201 CD1 
325 1 Y 1 R LEU 65  ? CD2 ? D LEU 201 CD2 
326 1 Y 1 R VAL 76  ? CG1 ? D VAL 212 CG1 
327 1 Y 1 R VAL 76  ? CG2 ? D VAL 212 CG2 
328 1 Y 1 R THR 78  ? OG1 ? D THR 214 OG1 
329 1 Y 1 R THR 78  ? CG2 ? D THR 214 CG2 
330 1 Y 1 R VAL 79  ? CG1 ? D VAL 215 CG1 
331 1 Y 1 R VAL 79  ? CG2 ? D VAL 215 CG2 
332 1 Y 1 R ASN 81  ? CG  ? D ASN 217 CG  
333 1 Y 1 R ASN 81  ? OD1 ? D ASN 217 OD1 
334 1 Y 1 R ASN 81  ? ND2 ? D ASN 217 ND2 
335 1 Y 1 R THR 82  ? OG1 ? D THR 218 OG1 
336 1 Y 1 R THR 82  ? CG2 ? D THR 218 CG2 
337 1 Y 1 R VAL 83  ? CG1 ? D VAL 219 CG1 
338 1 Y 1 R VAL 83  ? CG2 ? D VAL 219 CG2 
339 1 Y 1 R PHE 86  ? CG  ? D PHE 222 CG  
340 1 Y 1 R PHE 86  ? CD1 ? D PHE 222 CD1 
341 1 Y 1 R PHE 86  ? CD2 ? D PHE 222 CD2 
342 1 Y 1 R PHE 86  ? CE1 ? D PHE 222 CE1 
343 1 Y 1 R PHE 86  ? CE2 ? D PHE 222 CE2 
344 1 Y 1 R PHE 86  ? CZ  ? D PHE 222 CZ  
345 1 Y 1 R LYS 92  ? CG  ? D LYS 228 CG  
346 1 Y 1 R LYS 92  ? CD  ? D LYS 228 CD  
347 1 Y 1 R LYS 92  ? CE  ? D LYS 228 CE  
348 1 Y 1 R LYS 92  ? NZ  ? D LYS 228 NZ  
349 1 Y 1 R LEU 94  ? CG  ? D LEU 230 CG  
350 1 Y 1 R LEU 94  ? CD1 ? D LEU 230 CD1 
351 1 Y 1 R LEU 94  ? CD2 ? D LEU 230 CD2 
352 1 Y 1 R GLN 95  ? CG  ? D GLN 231 CG  
353 1 Y 1 R GLN 95  ? CD  ? D GLN 231 CD  
354 1 Y 1 R GLN 95  ? OE1 ? D GLN 231 OE1 
355 1 Y 1 R GLN 95  ? NE2 ? D GLN 231 NE2 
356 1 Y 1 R GLN 98  ? CG  ? D GLN 234 CG  
357 1 Y 1 R GLN 98  ? CD  ? D GLN 234 CD  
358 1 Y 1 R GLN 98  ? OE1 ? D GLN 234 OE1 
359 1 Y 1 R GLN 98  ? NE2 ? D GLN 234 NE2 
360 1 Y 1 R THR 100 ? OG1 ? D THR 236 OG1 
361 1 Y 1 R THR 100 ? CG2 ? D THR 236 CG2 
362 1 Y 1 R VAL 101 ? CG1 ? D VAL 237 CG1 
363 1 Y 1 R VAL 101 ? CG2 ? D VAL 237 CG2 
364 1 Y 1 R SER 111 ? OG  ? D SER 247 OG  
365 1 Y 1 R ASP 112 ? CG  ? D ASP 248 CG  
366 1 Y 1 R ASP 112 ? OD1 ? D ASP 248 OD1 
367 1 Y 1 R ASP 112 ? OD2 ? D ASP 248 OD2 
368 1 Y 1 R LEU 113 ? CG  ? D LEU 249 CG  
369 1 Y 1 R LEU 113 ? CD1 ? D LEU 249 CD1 
370 1 Y 1 R LEU 113 ? CD2 ? D LEU 249 CD2 
371 1 Y 1 R LEU 114 ? CG  ? D LEU 250 CG  
372 1 Y 1 R LEU 114 ? CD1 ? D LEU 250 CD1 
373 1 Y 1 R LEU 114 ? CD2 ? D LEU 250 CD2 
374 1 Y 1 R THR 115 ? OG1 ? D THR 251 OG1 
375 1 Y 1 R THR 115 ? CG2 ? D THR 251 CG2 
376 1 Y 1 R VAL 122 ? CG1 ? D VAL 258 CG1 
377 1 Y 1 R VAL 122 ? CG2 ? D VAL 258 CG2 
378 1 Y 1 R GLU 123 ? CG  ? D GLU 259 CG  
379 1 Y 1 R GLU 123 ? CD  ? D GLU 259 CD  
380 1 Y 1 R GLU 123 ? OE1 ? D GLU 259 OE1 
381 1 Y 1 R GLU 123 ? OE2 ? D GLU 259 OE2 
382 1 Y 1 R ASN 126 ? CG  ? D ASN 262 CG  
383 1 Y 1 R ASN 126 ? OD1 ? D ASN 262 OD1 
384 1 Y 1 R ASN 126 ? ND2 ? D ASN 262 ND2 
385 1 Y 1 R ILE 128 ? CG1 ? D ILE 264 CG1 
386 1 Y 1 R ILE 128 ? CG2 ? D ILE 264 CG2 
387 1 Y 1 R ILE 128 ? CD1 ? D ILE 264 CD1 
388 1 Y 1 R VAL 130 ? CG1 ? D VAL 266 CG1 
389 1 Y 1 R VAL 130 ? CG2 ? D VAL 266 CG2 
390 1 Y 1 R HIS 131 ? CG  ? D HIS 267 CG  
391 1 Y 1 R HIS 131 ? ND1 ? D HIS 267 ND1 
392 1 Y 1 R HIS 131 ? CD2 ? D HIS 267 CD2 
393 1 Y 1 R HIS 131 ? CE1 ? D HIS 267 CE1 
394 1 Y 1 R HIS 131 ? NE2 ? D HIS 267 NE2 
395 1 Y 1 R HIS 132 ? CG  ? D HIS 268 CG  
396 1 Y 1 R HIS 132 ? ND1 ? D HIS 268 ND1 
397 1 Y 1 R HIS 132 ? CD2 ? D HIS 268 CD2 
398 1 Y 1 R HIS 132 ? CE1 ? D HIS 268 CE1 
399 1 Y 1 R HIS 132 ? NE2 ? D HIS 268 NE2 
400 1 Y 1 R TRP 134 ? CG  ? D TRP 270 CG  
401 1 Y 1 R TRP 134 ? CD1 ? D TRP 270 CD1 
402 1 Y 1 R TRP 134 ? CD2 ? D TRP 270 CD2 
403 1 Y 1 R TRP 134 ? NE1 ? D TRP 270 NE1 
404 1 Y 1 R TRP 134 ? CE2 ? D TRP 270 CE2 
405 1 Y 1 R TRP 134 ? CE3 ? D TRP 270 CE3 
406 1 Y 1 R TRP 134 ? CZ2 ? D TRP 270 CZ2 
407 1 Y 1 R TRP 134 ? CZ3 ? D TRP 270 CZ3 
408 1 Y 1 R TRP 134 ? CH2 ? D TRP 270 CH2 
409 1 Y 1 R PHE 136 ? CG  ? D PHE 272 CG  
410 1 Y 1 R PHE 136 ? CD1 ? D PHE 272 CD1 
411 1 Y 1 R PHE 136 ? CD2 ? D PHE 272 CD2 
412 1 Y 1 R PHE 136 ? CE1 ? D PHE 272 CE1 
413 1 Y 1 R PHE 136 ? CE2 ? D PHE 272 CE2 
414 1 Y 1 R PHE 136 ? CZ  ? D PHE 272 CZ  
415 1 Y 1 R ASP 138 ? CG  ? D ASP 274 CG  
416 1 Y 1 R ASP 138 ? OD1 ? D ASP 274 OD1 
417 1 Y 1 R ASP 138 ? OD2 ? D ASP 274 OD2 
418 1 Y 1 R ARG 142 ? CG  ? D ARG 278 CG  
419 1 Y 1 R ARG 142 ? CD  ? D ARG 278 CD  
420 1 Y 1 R ARG 142 ? NE  ? D ARG 278 NE  
421 1 Y 1 R ARG 142 ? CZ  ? D ARG 278 CZ  
422 1 Y 1 R ARG 142 ? NH1 ? D ARG 278 NH1 
423 1 Y 1 R ARG 142 ? NH2 ? D ARG 278 NH2 
424 1 Y 1 R TYR 144 ? CG  ? D TYR 280 CG  
425 1 Y 1 R TYR 144 ? CD1 ? D TYR 280 CD1 
426 1 Y 1 R TYR 144 ? CD2 ? D TYR 280 CD2 
427 1 Y 1 R TYR 144 ? CE1 ? D TYR 280 CE1 
428 1 Y 1 R TYR 144 ? CE2 ? D TYR 280 CE2 
429 1 Y 1 R TYR 144 ? CZ  ? D TYR 280 CZ  
430 1 Y 1 R TYR 144 ? OH  ? D TYR 280 OH  
431 1 Y 1 R LEU 147 ? CG  ? D LEU 283 CG  
432 1 Y 1 R LEU 147 ? CD1 ? D LEU 283 CD1 
433 1 Y 1 R LEU 147 ? CD2 ? D LEU 283 CD2 
434 1 Y 1 R ASP 149 ? CG  ? D ASP 285 CG  
435 1 Y 1 R ASP 149 ? OD1 ? D ASP 285 OD1 
436 1 Y 1 R ASP 149 ? OD2 ? D ASP 285 OD2 
437 1 Y 1 R LEU 157 ? CG  ? D LEU 293 CG  
438 1 Y 1 R LEU 157 ? CD1 ? D LEU 293 CD1 
439 1 Y 1 R LEU 157 ? CD2 ? D LEU 293 CD2 
440 1 Y 1 R ASN 158 ? CG  ? D ASN 294 CG  
441 1 Y 1 R ASN 158 ? OD1 ? D ASN 294 OD1 
442 1 Y 1 R ASN 158 ? ND2 ? D ASN 294 ND2 
443 1 Y 1 R GLU 165 ? CG  ? D GLU 301 CG  
444 1 Y 1 R GLU 165 ? CD  ? D GLU 301 CD  
445 1 Y 1 R GLU 165 ? OE1 ? D GLU 301 OE1 
446 1 Y 1 R GLU 165 ? OE2 ? D GLU 301 OE2 
447 1 Y 1 R PHE 174 ? CG  ? D PHE 310 CG  
448 1 Y 1 R PHE 174 ? CD1 ? D PHE 310 CD1 
449 1 Y 1 R PHE 174 ? CD2 ? D PHE 310 CD2 
450 1 Y 1 R PHE 174 ? CE1 ? D PHE 310 CE1 
451 1 Y 1 R PHE 174 ? CE2 ? D PHE 310 CE2 
452 1 Y 1 R PHE 174 ? CZ  ? D PHE 310 CZ  
453 1 Y 1 R LYS 175 ? CG  ? D LYS 311 CG  
454 1 Y 1 R LYS 175 ? CD  ? D LYS 311 CD  
455 1 Y 1 R LYS 175 ? CE  ? D LYS 311 CE  
456 1 Y 1 R LYS 175 ? NZ  ? D LYS 311 NZ  
457 1 Y 1 R LYS 177 ? CG  ? D LYS 313 CG  
458 1 Y 1 R LYS 177 ? CD  ? D LYS 313 CD  
459 1 Y 1 R LYS 177 ? CE  ? D LYS 313 CE  
460 1 Y 1 R LYS 177 ? NZ  ? D LYS 313 NZ  
461 1 Y 1 R THR 178 ? OG1 ? D THR 314 OG1 
462 1 Y 1 R THR 178 ? CG2 ? D THR 314 CG2 
463 1 Y 1 R LEU 179 ? CG  ? D LEU 315 CG  
464 1 Y 1 R LEU 179 ? CD1 ? D LEU 315 CD1 
465 1 Y 1 R LEU 179 ? CD2 ? D LEU 315 CD2 
466 1 Y 1 R MET 180 ? CG  ? D MET 316 CG  
467 1 Y 1 R MET 180 ? SD  ? D MET 316 SD  
468 1 Y 1 R MET 180 ? CE  ? D MET 316 CE  
469 1 Y 1 R SER 183 ? OG  ? D SER 319 OG  
470 1 Y 1 R LYS 186 ? CG  ? D LYS 322 CG  
471 1 Y 1 R LYS 186 ? CD  ? D LYS 322 CD  
472 1 Y 1 R LYS 186 ? CE  ? D LYS 322 CE  
473 1 Y 1 R LYS 186 ? NZ  ? D LYS 322 NZ  
474 1 Y 1 R LYS 187 ? CG  ? D LYS 323 CG  
475 1 Y 1 R LYS 187 ? CD  ? D LYS 323 CD  
476 1 Y 1 R LYS 187 ? CE  ? D LYS 323 CE  
477 1 Y 1 R LYS 187 ? NZ  ? D LYS 323 NZ  
478 1 Y 1 R SER 190 ? OG  ? D SER 326 OG  
479 1 Y 1 R ILE 192 ? CG1 ? D ILE 328 CG1 
480 1 Y 1 R ILE 192 ? CG2 ? D ILE 328 CG2 
481 1 Y 1 R ILE 192 ? CD1 ? D ILE 328 CD1 
482 1 Y 1 R LEU 194 ? CG  ? D LEU 330 CG  
483 1 Y 1 R LEU 194 ? CD1 ? D LEU 330 CD1 
484 1 Y 1 R LEU 194 ? CD2 ? D LEU 330 CD2 
485 1 Y 1 R SER 196 ? OG  ? D SER 332 OG  
486 1 Y 1 R LEU 198 ? CG  ? D LEU 334 CG  
487 1 Y 1 R LEU 198 ? CD1 ? D LEU 334 CD1 
488 1 Y 1 R LEU 198 ? CD2 ? D LEU 334 CD2 
489 1 Y 1 R VAL 201 ? CG1 ? D VAL 337 CG1 
490 1 Y 1 R VAL 201 ? CG2 ? D VAL 337 CG2 
491 1 Y 1 R LEU 204 ? CG  ? D LEU 340 CG  
492 1 Y 1 R LEU 204 ? CD1 ? D LEU 340 CD1 
493 1 Y 1 R LEU 204 ? CD2 ? D LEU 340 CD2 
494 1 Y 1 R MET 207 ? CG  ? D MET 343 CG  
495 1 Y 1 R MET 207 ? SD  ? D MET 343 SD  
496 1 Y 1 R MET 207 ? CE  ? D MET 343 CE  
497 1 Y 1 R GLU 209 ? CG  ? D GLU 345 CG  
498 1 Y 1 R GLU 209 ? CD  ? D GLU 345 CD  
499 1 Y 1 R GLU 209 ? OE1 ? D GLU 345 OE1 
500 1 Y 1 R GLU 209 ? OE2 ? D GLU 345 OE2 
501 1 Y 1 R GLN 210 ? CG  ? D GLN 346 CG  
502 1 Y 1 R GLN 210 ? CD  ? D GLN 346 CD  
503 1 Y 1 R GLN 210 ? OE1 ? D GLN 346 OE1 
504 1 Y 1 R GLN 210 ? NE2 ? D GLN 346 NE2 
505 1 Y 1 R ASN 211 ? CG  ? D ASN 347 CG  
506 1 Y 1 R ASN 211 ? OD1 ? D ASN 347 OD1 
507 1 Y 1 R ASN 211 ? ND2 ? D ASN 347 ND2 
508 1 Y 1 R ARG 212 ? CG  ? D ARG 348 CG  
509 1 Y 1 R ARG 212 ? CD  ? D ARG 348 CD  
510 1 Y 1 R ARG 212 ? NE  ? D ARG 348 NE  
511 1 Y 1 R ARG 212 ? CZ  ? D ARG 348 CZ  
512 1 Y 1 R ARG 212 ? NH1 ? D ARG 348 NH1 
513 1 Y 1 R ARG 212 ? NH2 ? D ARG 348 NH2 
514 1 Y 1 R SER 213 ? OG  ? D SER 349 OG  
515 1 Y 1 R ASP 215 ? CG  ? D ASP 351 CG  
516 1 Y 1 R ASP 215 ? OD1 ? D ASP 351 OD1 
517 1 Y 1 R ASP 215 ? OD2 ? D ASP 351 OD2 
518 1 Y 1 R GLN 217 ? CG  ? D GLN 353 CG  
519 1 Y 1 R GLN 217 ? CD  ? D GLN 353 CD  
520 1 Y 1 R GLN 217 ? OE1 ? D GLN 353 OE1 
521 1 Y 1 R GLN 217 ? NE2 ? D GLN 353 NE2 
522 1 Y 1 R HIS 218 ? CG  ? D HIS 354 CG  
523 1 Y 1 R HIS 218 ? ND1 ? D HIS 354 ND1 
524 1 Y 1 R HIS 218 ? CD2 ? D HIS 354 CD2 
525 1 Y 1 R HIS 218 ? CE1 ? D HIS 354 CE1 
526 1 Y 1 R HIS 218 ? NE2 ? D HIS 354 NE2 
527 1 Y 1 R LEU 222 ? CG  ? D LEU 358 CG  
528 1 Y 1 R LEU 222 ? CD1 ? D LEU 358 CD1 
529 1 Y 1 R LEU 222 ? CD2 ? D LEU 358 CD2 
530 1 Y 1 R VAL 223 ? CG1 ? D VAL 359 CG1 
531 1 Y 1 R VAL 223 ? CG2 ? D VAL 359 CG2 
532 1 Y 1 R THR 225 ? OG1 ? D THR 361 OG1 
533 1 Y 1 R THR 225 ? CG2 ? D THR 361 CG2 
534 1 Y 1 R THR 227 ? OG1 ? D THR 363 OG1 
535 1 Y 1 R THR 227 ? CG2 ? D THR 363 CG2 
536 1 Y 1 R ILE 228 ? CG1 ? D ILE 364 CG1 
537 1 Y 1 R ILE 228 ? CG2 ? D ILE 364 CG2 
538 1 Y 1 R ILE 228 ? CD1 ? D ILE 364 CD1 
539 1 Y 1 R HIS 229 ? CG  ? D HIS 365 CG  
540 1 Y 1 R HIS 229 ? ND1 ? D HIS 365 ND1 
541 1 Y 1 R HIS 229 ? CD2 ? D HIS 365 CD2 
542 1 Y 1 R HIS 229 ? CE1 ? D HIS 365 CE1 
543 1 Y 1 R HIS 229 ? NE2 ? D HIS 365 NE2 
544 1 Y 1 R THR 230 ? OG1 ? D THR 366 OG1 
545 1 Y 1 R THR 230 ? CG2 ? D THR 366 CG2 
546 1 Y 1 R VAL 233 ? CG1 ? D VAL 369 CG1 
547 1 Y 1 R VAL 233 ? CG2 ? D VAL 369 CG2 
548 1 Y 1 R LYS 234 ? CG  ? D LYS 370 CG  
549 1 Y 1 R LYS 234 ? CD  ? D LYS 370 CD  
550 1 Y 1 R LYS 234 ? CE  ? D LYS 370 CE  
551 1 Y 1 R LYS 234 ? NZ  ? D LYS 370 NZ  
552 1 Y 1 R VAL 236 ? CG1 ? D VAL 372 CG1 
553 1 Y 1 R VAL 236 ? CG2 ? D VAL 372 CG2 
554 1 Y 1 R ILE 237 ? CG1 ? D ILE 373 CG1 
555 1 Y 1 R ILE 237 ? CG2 ? D ILE 373 CG2 
556 1 Y 1 R ILE 237 ? CD1 ? D ILE 373 CD1 
557 1 Y 1 R GLN 238 ? CG  ? D GLN 374 CG  
558 1 Y 1 R GLN 238 ? CD  ? D GLN 374 CD  
559 1 Y 1 R GLN 238 ? OE1 ? D GLN 374 OE1 
560 1 Y 1 R GLN 238 ? NE2 ? D GLN 374 NE2 
561 1 Y 1 R VAL 239 ? CG1 ? D VAL 375 CG1 
562 1 Y 1 R VAL 239 ? CG2 ? D VAL 375 CG2 
563 1 Y 1 R THR 241 ? OG1 ? D THR 377 OG1 
564 1 Y 1 R THR 241 ? CG2 ? D THR 377 CG2 
565 1 Y 1 R PHE 242 ? CG  ? D PHE 378 CG  
566 1 Y 1 R PHE 242 ? CD1 ? D PHE 378 CD1 
567 1 Y 1 R PHE 242 ? CD2 ? D PHE 378 CD2 
568 1 Y 1 R PHE 242 ? CE1 ? D PHE 378 CE1 
569 1 Y 1 R PHE 242 ? CE2 ? D PHE 378 CE2 
570 1 Y 1 R PHE 242 ? CZ  ? D PHE 378 CZ  
571 1 Y 1 R MET 243 ? CG  ? D MET 379 CG  
572 1 Y 1 R MET 243 ? SD  ? D MET 379 SD  
573 1 Y 1 R MET 243 ? CE  ? D MET 379 CE  
574 1 Y 1 R SER 244 ? OG  ? D SER 380 OG  
575 1 Y 1 R PHE 245 ? CG  ? D PHE 381 CG  
576 1 Y 1 R PHE 245 ? CD1 ? D PHE 381 CD1 
577 1 Y 1 R PHE 245 ? CD2 ? D PHE 381 CD2 
578 1 Y 1 R PHE 245 ? CE1 ? D PHE 381 CE1 
579 1 Y 1 R PHE 245 ? CE2 ? D PHE 381 CE2 
580 1 Y 1 R PHE 245 ? CZ  ? D PHE 381 CZ  
581 1 Y 1 R ILE 246 ? CG1 ? D ILE 382 CG1 
582 1 Y 1 R ILE 246 ? CG2 ? D ILE 382 CG2 
583 1 Y 1 R ILE 246 ? CD1 ? D ILE 382 CD1 
584 1 Y 1 R MET 249 ? CG  ? D MET 385 CG  
585 1 Y 1 R MET 249 ? SD  ? D MET 385 SD  
586 1 Y 1 R MET 249 ? CE  ? D MET 385 CE  
587 1 Y 1 R VAL 250 ? CG1 ? D VAL 386 CG1 
588 1 Y 1 R VAL 250 ? CG2 ? D VAL 386 CG2 
589 1 Y 1 R ILE 252 ? CG1 ? D ILE 388 CG1 
590 1 Y 1 R ILE 252 ? CG2 ? D ILE 388 CG2 
591 1 Y 1 R ILE 252 ? CD1 ? D ILE 388 CD1 
592 1 Y 1 R SER 253 ? OG  ? D SER 389 OG  
593 1 Y 1 R ASN 256 ? CG  ? D ASN 392 CG  
594 1 Y 1 R ASN 256 ? OD1 ? D ASN 392 OD1 
595 1 Y 1 R ASN 256 ? ND2 ? D ASN 392 ND2 
596 1 Y 1 R ASN 261 ? CG  ? D ASN 397 CG  
597 1 Y 1 R ASN 261 ? OD1 ? D ASN 397 OD1 
598 1 Y 1 R ASN 261 ? ND2 ? D ASN 397 ND2 
599 1 Y 1 R LYS 262 ? CG  ? D LYS 398 CG  
600 1 Y 1 R LYS 262 ? CD  ? D LYS 398 CD  
601 1 Y 1 R LYS 262 ? CE  ? D LYS 398 CE  
602 1 Y 1 R LYS 262 ? NZ  ? D LYS 398 NZ  
603 1 Y 1 R LEU 263 ? CG  ? D LEU 399 CG  
604 1 Y 1 R LEU 263 ? CD1 ? D LEU 399 CD1 
605 1 Y 1 R LEU 263 ? CD2 ? D LEU 399 CD2 
606 1 Y 1 R THR 264 ? OG1 ? D THR 400 OG1 
607 1 Y 1 R THR 264 ? CG2 ? D THR 400 CG2 
608 1 Y 1 R VAL 265 ? CG1 ? D VAL 401 CG1 
609 1 Y 1 R VAL 265 ? CG2 ? D VAL 401 CG2 
610 1 Y 1 R MET 266 ? CG  ? D MET 402 CG  
611 1 Y 1 R MET 266 ? SD  ? D MET 402 SD  
612 1 Y 1 R MET 266 ? CE  ? D MET 402 CE  
613 1 Y 1 R VAL 267 ? CG1 ? D VAL 403 CG1 
614 1 Y 1 R VAL 267 ? CG2 ? D VAL 403 CG2 
615 1 Y 1 R ARG 299 ? CG  ? D ARG 435 CG  
616 1 Y 1 R ARG 299 ? CD  ? D ARG 435 CD  
617 1 Y 1 R ARG 299 ? NE  ? D ARG 435 NE  
618 1 Y 1 R ARG 299 ? CZ  ? D ARG 435 CZ  
619 1 Y 1 R ARG 299 ? NH1 ? D ARG 435 NH1 
620 1 Y 1 R ARG 299 ? NH2 ? D ARG 435 NH2 
621 1 Y 1 R HIS 300 ? CG  ? D HIS 436 CG  
622 1 Y 1 R HIS 300 ? ND1 ? D HIS 436 ND1 
623 1 Y 1 R HIS 300 ? CD2 ? D HIS 436 CD2 
624 1 Y 1 R HIS 300 ? CE1 ? D HIS 436 CE1 
625 1 Y 1 R HIS 300 ? NE2 ? D HIS 436 NE2 
626 1 Y 1 R ARG 303 ? CG  ? D ARG 439 CG  
627 1 Y 1 R ARG 303 ? CD  ? D ARG 439 CD  
628 1 Y 1 R ARG 303 ? NE  ? D ARG 439 NE  
629 1 Y 1 R ARG 303 ? CZ  ? D ARG 439 CZ  
630 1 Y 1 R ARG 303 ? NH1 ? D ARG 439 NH1 
631 1 Y 1 R ARG 303 ? NH2 ? D ARG 439 NH2 
632 1 Y 1 R ARG 306 ? CG  ? D ARG 442 CG  
633 1 Y 1 R ARG 306 ? CD  ? D ARG 442 CD  
634 1 Y 1 R ARG 306 ? NE  ? D ARG 442 NE  
635 1 Y 1 R ARG 306 ? CZ  ? D ARG 442 CZ  
636 1 Y 1 R ARG 306 ? NH1 ? D ARG 442 NH1 
637 1 Y 1 R ARG 306 ? NH2 ? D ARG 442 NH2 
638 1 Y 1 R ILE 310 ? CG1 ? D ILE 446 CG1 
639 1 Y 1 R ILE 310 ? CG2 ? D ILE 446 CG2 
640 1 Y 1 R ILE 310 ? CD1 ? D ILE 446 CD1 
641 1 Y 1 R PHE 312 ? CG  ? D PHE 448 CG  
642 1 Y 1 R PHE 312 ? CD1 ? D PHE 448 CD1 
643 1 Y 1 R PHE 312 ? CD2 ? D PHE 448 CD2 
644 1 Y 1 R PHE 312 ? CE1 ? D PHE 448 CE1 
645 1 Y 1 R PHE 312 ? CE2 ? D PHE 448 CE2 
646 1 Y 1 R PHE 312 ? CZ  ? D PHE 448 CZ  
647 1 Y 1 R VAL 313 ? CG1 ? D VAL 449 CG1 
648 1 Y 1 R VAL 313 ? CG2 ? D VAL 449 CG2 
649 1 Y 1 R ARG 323 ? CG  ? D ARG 459 CG  
650 1 Y 1 R ARG 323 ? CD  ? D ARG 459 CD  
651 1 Y 1 R ARG 323 ? NE  ? D ARG 459 NE  
652 1 Y 1 R ARG 323 ? CZ  ? D ARG 459 CZ  
653 1 Y 1 R ARG 323 ? NH1 ? D ARG 459 NH1 
654 1 Y 1 R ARG 323 ? NH2 ? D ARG 459 NH2 
655 1 Y 1 R MET 325 ? CG  ? D MET 461 CG  
656 1 Y 1 R MET 325 ? SD  ? D MET 461 SD  
657 1 Y 1 R MET 325 ? CE  ? D MET 461 CE  
658 1 Y 1 R PHE 326 ? CG  ? D PHE 462 CG  
659 1 Y 1 R PHE 326 ? CD1 ? D PHE 462 CD1 
660 1 Y 1 R PHE 326 ? CD2 ? D PHE 462 CD2 
661 1 Y 1 R PHE 326 ? CE1 ? D PHE 462 CE1 
662 1 Y 1 R PHE 326 ? CE2 ? D PHE 462 CE2 
663 1 Y 1 R PHE 326 ? CZ  ? D PHE 462 CZ  
664 1 Y 1 R CYS 327 ? SG  ? D CYS 463 SG  
665 1 Y 1 R TYR 328 ? CG  ? D TYR 464 CG  
666 1 Y 1 R TYR 328 ? CD1 ? D TYR 464 CD1 
667 1 Y 1 R TYR 328 ? CD2 ? D TYR 464 CD2 
668 1 Y 1 R TYR 328 ? CE1 ? D TYR 464 CE1 
669 1 Y 1 R TYR 328 ? CE2 ? D TYR 464 CE2 
670 1 Y 1 R TYR 328 ? CZ  ? D TYR 464 CZ  
671 1 Y 1 R TYR 328 ? OH  ? D TYR 464 OH  
672 1 Y 1 R ILE 329 ? CG1 ? D ILE 465 CG1 
673 1 Y 1 R ILE 329 ? CG2 ? D ILE 465 CG2 
674 1 Y 1 R ILE 329 ? CD1 ? D ILE 465 CD1 
675 1 Y 1 R SER 330 ? OG  ? D SER 466 OG  
676 1 Y 1 R ASP 331 ? CG  ? D ASP 467 CG  
677 1 Y 1 R ASP 331 ? OD1 ? D ASP 467 OD1 
678 1 Y 1 R ASP 331 ? OD2 ? D ASP 467 OD2 
679 1 Y 1 R GLU 332 ? CG  ? D GLU 468 CG  
680 1 Y 1 R GLU 332 ? CD  ? D GLU 468 CD  
681 1 Y 1 R GLU 332 ? OE1 ? D GLU 468 OE1 
682 1 Y 1 R GLU 332 ? OE2 ? D GLU 468 OE2 
683 1 Y 1 R GLN 333 ? CG  ? D GLN 469 CG  
684 1 Y 1 R GLN 333 ? CD  ? D GLN 469 CD  
685 1 Y 1 R GLN 333 ? OE1 ? D GLN 469 OE1 
686 1 Y 1 R GLN 333 ? NE2 ? D GLN 469 NE2 
687 1 Y 1 R TRP 334 ? CG  ? D TRP 470 CG  
688 1 Y 1 R TRP 334 ? CD1 ? D TRP 470 CD1 
689 1 Y 1 R TRP 334 ? CD2 ? D TRP 470 CD2 
690 1 Y 1 R TRP 334 ? NE1 ? D TRP 470 NE1 
691 1 Y 1 R TRP 334 ? CE2 ? D TRP 470 CE2 
692 1 Y 1 R TRP 334 ? CE3 ? D TRP 470 CE3 
693 1 Y 1 R TRP 334 ? CZ2 ? D TRP 470 CZ2 
694 1 Y 1 R TRP 334 ? CZ3 ? D TRP 470 CZ3 
695 1 Y 1 R TRP 334 ? CH2 ? D TRP 470 CH2 
696 1 Y 1 R THR 335 ? OG1 ? D THR 471 OG1 
697 1 Y 1 R THR 335 ? CG2 ? D THR 471 CG2 
698 1 Y 1 R PRO 336 ? CG  ? D PRO 472 CG  
699 1 Y 1 R PRO 336 ? CD  ? D PRO 472 CD  
700 1 Y 1 R PHE 337 ? CG  ? D PHE 473 CG  
701 1 Y 1 R PHE 337 ? CD1 ? D PHE 473 CD1 
702 1 Y 1 R PHE 337 ? CD2 ? D PHE 473 CD2 
703 1 Y 1 R PHE 337 ? CE1 ? D PHE 473 CE1 
704 1 Y 1 R PHE 337 ? CE2 ? D PHE 473 CE2 
705 1 Y 1 R PHE 337 ? CZ  ? D PHE 473 CZ  
706 1 Y 1 R LEU 338 ? CG  ? D LEU 474 CG  
707 1 Y 1 R LEU 338 ? CD1 ? D LEU 474 CD1 
708 1 Y 1 R LEU 338 ? CD2 ? D LEU 474 CD2 
709 1 Y 1 R TYR 339 ? CG  ? D TYR 475 CG  
710 1 Y 1 R TYR 339 ? CD1 ? D TYR 475 CD1 
711 1 Y 1 R TYR 339 ? CD2 ? D TYR 475 CD2 
712 1 Y 1 R TYR 339 ? CE1 ? D TYR 475 CE1 
713 1 Y 1 R TYR 339 ? CE2 ? D TYR 475 CE2 
714 1 Y 1 R TYR 339 ? CZ  ? D TYR 475 CZ  
715 1 Y 1 R TYR 339 ? OH  ? D TYR 475 OH  
716 1 Y 1 R ASP 340 ? CG  ? D ASP 476 CG  
717 1 Y 1 R ASP 340 ? OD1 ? D ASP 476 OD1 
718 1 Y 1 R ASP 340 ? OD2 ? D ASP 476 OD2 
719 1 Y 1 R PHE 341 ? CG  ? D PHE 477 CG  
720 1 Y 1 R PHE 341 ? CD1 ? D PHE 477 CD1 
721 1 Y 1 R PHE 341 ? CD2 ? D PHE 477 CD2 
722 1 Y 1 R PHE 341 ? CE1 ? D PHE 477 CE1 
723 1 Y 1 R PHE 341 ? CE2 ? D PHE 477 CE2 
724 1 Y 1 R PHE 341 ? CZ  ? D PHE 477 CZ  
725 1 Y 1 R TYR 342 ? CG  ? D TYR 478 CG  
726 1 Y 1 R TYR 342 ? CD1 ? D TYR 478 CD1 
727 1 Y 1 R TYR 342 ? CD2 ? D TYR 478 CD2 
728 1 Y 1 R TYR 342 ? CE1 ? D TYR 478 CE1 
729 1 Y 1 R TYR 342 ? CE2 ? D TYR 478 CE2 
730 1 Y 1 R TYR 342 ? CZ  ? D TYR 478 CZ  
731 1 Y 1 R TYR 342 ? OH  ? D TYR 478 OH  
732 1 Y 1 R HIS 343 ? CG  ? D HIS 479 CG  
733 1 Y 1 R HIS 343 ? ND1 ? D HIS 479 ND1 
734 1 Y 1 R HIS 343 ? CD2 ? D HIS 479 CD2 
735 1 Y 1 R HIS 343 ? CE1 ? D HIS 479 CE1 
736 1 Y 1 R HIS 343 ? NE2 ? D HIS 479 NE2 
737 1 Y 1 R TYR 344 ? CG  ? D TYR 480 CG  
738 1 Y 1 R TYR 344 ? CD1 ? D TYR 480 CD1 
739 1 Y 1 R TYR 344 ? CD2 ? D TYR 480 CD2 
740 1 Y 1 R TYR 344 ? CE1 ? D TYR 480 CE1 
741 1 Y 1 R TYR 344 ? CE2 ? D TYR 480 CE2 
742 1 Y 1 R TYR 344 ? CZ  ? D TYR 480 CZ  
743 1 Y 1 R TYR 344 ? OH  ? D TYR 480 OH  
744 1 Y 1 R MET 347 ? CG  ? D MET 483 CG  
745 1 Y 1 R MET 347 ? SD  ? D MET 483 SD  
746 1 Y 1 R MET 347 ? CE  ? D MET 483 CE  
747 1 Y 1 R VAL 348 ? CG1 ? D VAL 484 CG1 
748 1 Y 1 R VAL 348 ? CG2 ? D VAL 484 CG2 
749 1 Y 1 R THR 349 ? OG1 ? D THR 485 OG1 
750 1 Y 1 R THR 349 ? CG2 ? D THR 485 CG2 
751 1 Y 1 R ASN 350 ? CG  ? D ASN 486 CG  
752 1 Y 1 R ASN 350 ? OD1 ? D ASN 486 OD1 
753 1 Y 1 R ASN 350 ? ND2 ? D ASN 486 ND2 
754 1 Y 1 R LEU 352 ? CG  ? D LEU 488 CG  
755 1 Y 1 R LEU 352 ? CD1 ? D LEU 488 CD1 
756 1 Y 1 R LEU 352 ? CD2 ? D LEU 488 CD2 
757 1 Y 1 R VAL 355 ? CG1 ? D VAL 491 CG1 
758 1 Y 1 R VAL 355 ? CG2 ? D VAL 491 CG2 
759 1 Y 1 R SER 356 ? OG  ? D SER 492 OG  
760 1 Y 1 R SER 357 ? OG  ? D SER 493 OG  
761 1 Y 1 R THR 358 ? OG1 ? D THR 494 OG1 
762 1 Y 1 R THR 358 ? CG2 ? D THR 494 CG2 
763 1 Y 1 R ILE 359 ? CG1 ? D ILE 495 CG1 
764 1 Y 1 R ILE 359 ? CG2 ? D ILE 495 CG2 
765 1 Y 1 R ILE 359 ? CD1 ? D ILE 495 CD1 
766 1 Y 1 R ASN 360 ? CG  ? D ASN 496 CG  
767 1 Y 1 R ASN 360 ? OD1 ? D ASN 496 OD1 
768 1 Y 1 R ASN 360 ? ND2 ? D ASN 496 ND2 
769 1 Y 1 R SER 368 ? OG  ? D SER 504 OG  
770 1 Y 1 R LEU 379 ? CG  ? D LEU 515 CG  
771 1 Y 1 R LEU 379 ? CD1 ? D LEU 515 CD1 
772 1 Y 1 R LEU 379 ? CD2 ? D LEU 515 CD2 
773 1 Y 1 L ILE 12  ? CG1 ? E ILE 5   CG1 
774 1 Y 1 L ILE 12  ? CG2 ? E ILE 5   CG2 
775 1 Y 1 L ILE 12  ? CD1 ? E ILE 5   CD1 
776 1 Y 1 L LEU 13  ? CG  ? E LEU 6   CG  
777 1 Y 1 L LEU 13  ? CD1 ? E LEU 6   CD1 
778 1 Y 1 L LEU 13  ? CD2 ? E LEU 6   CD2 
779 1 N 1 R PIO 501 ? C5B ? F PIO 1   C5B 
780 1 N 1 R PIO 501 ? C6A ? F PIO 1   C6A 
781 1 N 1 R PIO 501 ? C6B ? F PIO 1   C6B 
782 1 N 1 R PIO 501 ? C7A ? F PIO 1   C7A 
783 1 N 1 R PIO 501 ? C7B ? F PIO 1   C7B 
784 1 N 1 R PIO 501 ? C8A ? F PIO 1   C8A 
785 1 N 1 R PIO 501 ? C8B ? F PIO 1   C8B 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZYT 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZYT 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZYT 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ZYT 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 8112  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.571 ? 11120 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 8.532 ? 1215  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043 ? 1319  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1413  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZYT 
_struct.title                        
'Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin1 and SBI-553 (complex 3)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZYT 
_struct_keywords.text            
'neurotensin receptor, beta-arrestin1, phosphorylation, intracellular agonist, SBI-553, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
G N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP ARRB1_HUMAN P49407 ? 1 
;GDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFV
ANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKR
NSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADI
CLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSY
KVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTN
;
2  
2 PDB 8ZYT        8ZYT   ? 2 ? 1  
3 PDB 8ZYT        8ZYT   ? 3 ? 1  
4 UNP C562_ECOLX  P0ABE7 ? 4 
;ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYHQKY
;
23 
5 UNP NTR1_HUMAN  P30989 ? 4 
;MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVG
NTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVA
SLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYH
VRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKAD
SVSSNHTLSSNATRETLY
;
1  
6 PDB 8ZYT        8ZYT   ? 5 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZYT B 22  ? 402 ? P49407 2  ? 382 ? 1    381 
2 2 8ZYT D 1   ? 260 ? 8ZYT   1  ? 260 ? 1    260 
3 3 8ZYT Q 1   ? 235 ? 8ZYT   1  ? 235 ? 1    235 
4 4 8ZYT R 19  ? 123 ? P0ABE7 23 ? 127 ? -117 -13 
5 5 8ZYT R 137 ? 557 ? P30989 1  ? 418 ? 1    418 
6 6 8ZYT L 1   ? 6   ? 8ZYT   8  ? 13  ? 8    13  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8ZYT MET B 1   ? UNP P49407 ?   ?   'initiating methionine' -20  1  
1 8ZYT GLY B 2   ? UNP P49407 ?   ?   'expression tag'        -19  2  
1 8ZYT SER B 3   ? UNP P49407 ?   ?   'expression tag'        -18  3  
1 8ZYT HIS B 4   ? UNP P49407 ?   ?   'expression tag'        -17  4  
1 8ZYT HIS B 5   ? UNP P49407 ?   ?   'expression tag'        -16  5  
1 8ZYT HIS B 6   ? UNP P49407 ?   ?   'expression tag'        -15  6  
1 8ZYT HIS B 7   ? UNP P49407 ?   ?   'expression tag'        -14  7  
1 8ZYT HIS B 8   ? UNP P49407 ?   ?   'expression tag'        -13  8  
1 8ZYT HIS B 9   ? UNP P49407 ?   ?   'expression tag'        -12  9  
1 8ZYT HIS B 10  ? UNP P49407 ?   ?   'expression tag'        -11  10 
1 8ZYT HIS B 11  ? UNP P49407 ?   ?   'expression tag'        -10  11 
1 8ZYT GLY B 12  ? UNP P49407 ?   ?   'expression tag'        -9   12 
1 8ZYT SER B 13  ? UNP P49407 ?   ?   'expression tag'        -8   13 
1 8ZYT LEU B 14  ? UNP P49407 ?   ?   'expression tag'        -7   14 
1 8ZYT GLU B 15  ? UNP P49407 ?   ?   'expression tag'        -6   15 
1 8ZYT VAL B 16  ? UNP P49407 ?   ?   'expression tag'        -5   16 
1 8ZYT LEU B 17  ? UNP P49407 ?   ?   'expression tag'        -4   17 
1 8ZYT PHE B 18  ? UNP P49407 ?   ?   'expression tag'        -3   18 
1 8ZYT GLN B 19  ? UNP P49407 ?   ?   'expression tag'        -2   19 
1 8ZYT GLY B 20  ? UNP P49407 ?   ?   'expression tag'        -1   20 
1 8ZYT PRO B 21  ? UNP P49407 ?   ?   'expression tag'        0    21 
4 8ZYT MET R 1   ? UNP P0ABE7 ?   ?   'initiating methionine' -135 22 
4 8ZYT LYS R 2   ? UNP P0ABE7 ?   ?   'expression tag'        -134 23 
4 8ZYT THR R 3   ? UNP P0ABE7 ?   ?   'expression tag'        -133 24 
4 8ZYT ILE R 4   ? UNP P0ABE7 ?   ?   'expression tag'        -132 25 
4 8ZYT ILE R 5   ? UNP P0ABE7 ?   ?   'expression tag'        -131 26 
4 8ZYT ALA R 6   ? UNP P0ABE7 ?   ?   'expression tag'        -130 27 
4 8ZYT LEU R 7   ? UNP P0ABE7 ?   ?   'expression tag'        -129 28 
4 8ZYT SER R 8   ? UNP P0ABE7 ?   ?   'expression tag'        -128 29 
4 8ZYT TYR R 9   ? UNP P0ABE7 ?   ?   'expression tag'        -127 30 
4 8ZYT ILE R 10  ? UNP P0ABE7 ?   ?   'expression tag'        -126 31 
4 8ZYT PHE R 11  ? UNP P0ABE7 ?   ?   'expression tag'        -125 32 
4 8ZYT CYS R 12  ? UNP P0ABE7 ?   ?   'expression tag'        -124 33 
4 8ZYT LEU R 13  ? UNP P0ABE7 ?   ?   'expression tag'        -123 34 
4 8ZYT VAL R 14  ? UNP P0ABE7 ?   ?   'expression tag'        -122 35 
4 8ZYT PHE R 15  ? UNP P0ABE7 ?   ?   'expression tag'        -121 36 
4 8ZYT ALA R 16  ? UNP P0ABE7 ?   ?   'expression tag'        -120 37 
4 8ZYT GLY R 17  ? UNP P0ABE7 ?   ?   'expression tag'        -119 38 
4 8ZYT SER R 18  ? UNP P0ABE7 ?   ?   'expression tag'        -118 39 
4 8ZYT TRP R 25  ? UNP P0ABE7 MET 29  conflict                -111 40 
4 8ZYT ILE R 120 ? UNP P0ABE7 HIS 124 conflict                -16  41 
4 8ZYT LEU R 124 ? UNP P0ABE7 ?   ?   linker                  -12  42 
4 8ZYT ALA R 125 ? UNP P0ABE7 ?   ?   linker                  -11  43 
4 8ZYT SER R 126 ? UNP P0ABE7 ?   ?   linker                  -10  44 
4 8ZYT GLY R 127 ? UNP P0ABE7 ?   ?   linker                  -9   45 
4 8ZYT SER R 128 ? UNP P0ABE7 ?   ?   linker                  -8   46 
4 8ZYT LEU R 129 ? UNP P0ABE7 ?   ?   linker                  -7   47 
4 8ZYT GLU R 130 ? UNP P0ABE7 ?   ?   linker                  -6   48 
4 8ZYT VAL R 131 ? UNP P0ABE7 ?   ?   linker                  -5   49 
4 8ZYT LEU R 132 ? UNP P0ABE7 ?   ?   linker                  -4   50 
4 8ZYT PHE R 133 ? UNP P0ABE7 ?   ?   linker                  -3   51 
4 8ZYT GLN R 134 ? UNP P0ABE7 ?   ?   linker                  -2   52 
4 8ZYT GLY R 135 ? UNP P0ABE7 ?   ?   linker                  -1   53 
4 8ZYT PRO R 136 ? UNP P0ABE7 ?   ?   linker                  0    54 
5 8ZYT LEU R 306 ? UNP P30989 ILE 170 conflict                170  55 
5 8ZYT ILE R 512 ? UNP P30989 LEU 376 conflict                376  56 
5 8ZYT CYS R 530 N UNP P30989 ?   ?   insertion               380  57 
5 8ZYT PHE R 531 O UNP P30989 ?   ?   insertion               380  58 
5 8ZYT ASN R 532 P UNP P30989 ?   ?   insertion               380  59 
5 8ZYT CYS R 538 V UNP P30989 ALA 399 conflict                380  60 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 64  ? LYS A 69  ? ASP B 43  LYS B 48  1 ? 6  
HELX_P HELX_P2  AA2 THR A 118 ? GLY A 129 ? THR B 97  GLY B 108 1 ? 12 
HELX_P HELX_P3  AA3 ARG B 110 ? THR B 114 ? ARG D 110 THR D 114 5 ? 5  
HELX_P HELX_P4  AA4 SER B 186 ? ALA B 188 ? SER D 186 ALA D 188 5 ? 3  
HELX_P HELX_P5  AA5 PRO B 215 ? LEU B 219 ? PRO D 215 LEU D 219 5 ? 5  
HELX_P HELX_P6  AA6 GLN C 100 ? PHE C 104 ? GLN Q 100 PHE Q 104 5 ? 5  
HELX_P HELX_P7  AA7 SER C 142 ? SER C 148 ? SER Q 142 SER Q 148 1 ? 7  
HELX_P HELX_P8  AA8 ALA C 205 ? HIS C 210 ? ALA Q 205 HIS Q 210 1 ? 6  
HELX_P HELX_P9  AA9 ASP D 195 ? ARG D 226 ? ASP R 59  ARG R 90  1 ? 32 
HELX_P HELX_P10 AB1 THR D 236 ? ALA D 255 ? THR R 100 ALA R 119 1 ? 20 
HELX_P HELX_P11 AB2 ALA D 255 ? PHE D 263 ? ALA R 119 PHE R 127 1 ? 9  
HELX_P HELX_P12 AB3 ASP D 274 ? HIS D 308 ? ASP R 138 HIS R 172 1 ? 35 
HELX_P HELX_P13 AB4 HIS D 308 ? LEU D 315 ? HIS R 172 LEU R 179 1 ? 8  
HELX_P HELX_P14 AB5 SER D 317 ? LEU D 335 ? SER R 181 LEU R 199 1 ? 19 
HELX_P HELX_P15 AB6 ALA D 336 ? MET D 343 ? ALA R 200 MET R 207 1 ? 8  
HELX_P HELX_P16 AB7 HIS D 365 ? PHE D 381 ? HIS R 229 PHE R 245 1 ? 17 
HELX_P HELX_P17 AB8 ILE D 382 ? VAL D 403 ? ILE R 246 VAL R 267 1 ? 22 
HELX_P HELX_P18 AB9 GLY D 437 ? ARG D 439 ? GLY R 301 ARG R 303 5 ? 3  
HELX_P HELX_P19 AC1 VAL D 440 ? PHE D 462 ? VAL R 304 PHE R 326 1 ? 23 
HELX_P HELX_P20 AC2 THR D 471 ? SER D 504 ? THR R 335 SER R 368 1 ? 34 
HELX_P HELX_P21 AC3 ALA D 505 ? THR D 514 ? ALA R 369 THR R 378 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? B CYS 45  SG ? ? ? 1_555 B CYS 119 SG ? ? D CYS 45  D CYS 119 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ?    ? C CYS 155 SG ? ? ? 1_555 C CYS 215 SG ? ? Q CYS 155 Q CYS 215 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf3 disulf ?    ? D CYS 277 SG ? ? ? 1_555 D CYS 360 SG ? ? R CYS 141 R CYS 224 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
covale1 covale both ? D HIS 545 C  ? ? ? 1_555 D TPO 546 N  ? ? R HIS 406 R TPO 407 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale2 covale both ? D TPO 546 C  ? ? ? 1_555 D LEU 547 N  ? ? R TPO 407 R LEU 408 1_555 ? ? ? ? ? ? ? 1.326 ? ? 
covale3 covale both ? D LEU 547 C  ? ? ? 1_555 D SEP 548 N  ? ? R LEU 408 R SEP 409 1_555 ? ? ? ? ? ? ? 1.325 ? ? 
covale4 covale both ? D SEP 548 C  ? ? ? 1_555 D SEP 549 N  ? ? R SEP 409 R SEP 410 1_555 ? ? ? ? ? ? ? 1.325 ? ? 
covale5 covale both ? D SEP 549 C  ? ? ? 1_555 D ASN 550 N  ? ? R SEP 410 R ASN 411 1_555 ? ? ? ? ? ? ? 1.326 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO D 546 ? .   . .   . TPO R 407 ? 1_555 .   . .   . .     .  .  THR 1 TPO Phosphorylation 'Named protein modification' 
2 SEP D 548 ? .   . .   . SEP R 409 ? 1_555 .   . .   . .     .  .  SER 1 SEP Phosphorylation 'Named protein modification' 
3 SEP D 549 ? .   . .   . SEP R 410 ? 1_555 .   . .   . .     .  .  SER 1 SEP Phosphorylation 'Named protein modification' 
4 CYS B 45  ? CYS B 119 ? CYS D 45  ? 1_555 CYS D 119 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
5 CYS C 155 ? CYS C 215 ? CYS Q 155 ? 1_555 CYS Q 215 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
6 CYS D 277 ? CYS D 360 ? CYS R 141 ? 1_555 CYS R 224 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 5 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 3 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
AB5 ? 4 ? 
AB6 ? 4 ? 
AB7 ? 3 ? 
AB8 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB8 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 132 ? THR A 136 ? ALA B 111 THR B 115 
AA1 2 ASP A 58  ? VAL A 63  ? ASP B 37  VAL B 42  
AA1 3 LEU A 38  ? LEU A 42  ? LEU B 17  LEU B 21  
AA1 4 ARG A 27  ? ALA A 32  ? ARG B 6   ALA B 11  
AA1 5 LEU D 547 ? ASN D 550 ? LEU R 408 ASN R 411 
AA2 1 ASP A 46  ? VAL A 48  ? ASP B 25  VAL B 27  
AA2 2 SER A 183 ? VAL A 191 ? SER B 162 VAL B 170 
AA2 3 GLY A 161 ? ALA A 171 ? GLY B 140 ALA B 150 
AA2 4 ARG A 72  ? ARG A 82  ? ARG B 51  ARG B 61  
AA2 5 ASP A 98  ? GLN A 105 ? ASP B 77  GLN B 84  
AA3 1 VAL A 147 ? LEU A 149 ? VAL B 126 LEU B 128 
AA3 2 ALA A 308 ? ASP A 310 ? ALA B 287 ASP B 289 
AA4 1 THR A 206 ? ARG A 208 ? THR B 185 ARG B 187 
AA4 2 LEU A 217 ? LEU A 219 ? LEU B 196 LEU B 198 
AA4 3 ILE A 234 ? ASN A 242 ? ILE B 213 ASN B 221 
AA4 4 SER A 286 ? LEU A 294 ? SER B 265 LEU B 273 
AA5 1 ILE A 227 ? TYR A 229 ? ILE B 206 TYR B 208 
AA5 2 SER A 361 ? MET A 372 ? SER B 340 MET B 351 
AA5 3 ILE A 337 ? VAL A 349 ? ILE B 316 VAL B 328 
AA5 4 VAL A 248 ? CYS A 262 ? VAL B 227 CYS B 241 
AA5 5 THR A 266 ? ALA A 278 ? THR B 245 ALA B 257 
AA5 6 GLN D 231 ? SER D 232 ? GLN R 95  SER R 96  
AA6 1 GLN B 26  ? SER B 30  ? GLN D 26  SER D 30  
AA6 2 ARG B 42  ? SER B 48  ? ARG D 42  SER D 48  
AA6 3 THR B 101 ? GLN B 105 ? THR D 101 GLN D 105 
AA6 4 THR B 92  ? ASP B 96  ? THR D 92  ASP D 96  
AA7 1 THR B 81  ? TYR B 83  ? THR D 81  TYR D 83  
AA7 2 LEU B 68  ? ILE B 74  ? LEU D 68  ILE D 74  
AA7 3 SER B 55  ? GLN B 62  ? SER D 55  GLN D 62  
AA7 4 ALA B 115 ? ARG B 123 ? ALA D 115 ARG D 123 
AA7 5 TYR B 132 ? TRP B 133 ? TYR D 132 TRP D 133 
AA8 1 THR B 81  ? TYR B 83  ? THR D 81  TYR D 83  
AA8 2 LEU B 68  ? ILE B 74  ? LEU D 68  ILE D 74  
AA8 3 SER B 55  ? GLN B 62  ? SER D 55  GLN D 62  
AA8 4 ALA B 115 ? ARG B 123 ? ALA D 115 ARG D 123 
AA8 5 THR B 137 ? VAL B 139 ? THR D 137 VAL D 139 
AA9 1 SER B 150 ? LEU B 154 ? SER D 150 LEU D 154 
AA9 2 ALA B 166 ? TYR B 175 ? ALA D 166 TYR D 175 
AA9 3 TYR B 206 ? VAL B 214 ? TYR D 206 VAL D 214 
AA9 4 VAL B 193 ? THR B 195 ? VAL D 193 THR D 195 
AB1 1 SER B 150 ? LEU B 154 ? SER D 150 LEU D 154 
AB1 2 ALA B 166 ? TYR B 175 ? ALA D 166 TYR D 175 
AB1 3 TYR B 206 ? VAL B 214 ? TYR D 206 VAL D 214 
AB1 4 VAL B 199 ? LEU B 200 ? VAL D 199 LEU D 200 
AB2 1 THR B 181 ? TRP B 184 ? THR D 181 TRP D 184 
AB2 2 TYR B 224 ? ASN B 229 ? TYR D 224 ASN D 229 
AB2 3 LYS B 239 ? VAL B 241 ? LYS D 239 VAL D 241 
AB3 1 MET C 25  ? GLN C 27  ? MET Q 25  GLN Q 27  
AB3 2 VAL C 40  ? ALA C 46  ? VAL Q 40  ALA Q 46  
AB3 3 ASP C 91  ? ILE C 96  ? ASP Q 91  ILE Q 96  
AB3 4 PHE C 83  ? ARG C 87  ? PHE Q 83  ARG Q 87  
AB4 1 SER C 31  ? ALA C 34  ? SER Q 31  ALA Q 34  
AB4 2 THR C 123 ? ILE C 127 ? THR Q 123 ILE Q 127 
AB4 3 THR C 106 ? GLN C 111 ? THR Q 106 GLN Q 111 
AB4 4 VAL C 54  ? GLN C 59  ? VAL Q 54  GLN Q 59  
AB4 5 LYS C 66  ? TYR C 70  ? LYS Q 66  TYR Q 70  
AB4 6 SER C 74  ? LEU C 75  ? SER Q 74  LEU Q 75  
AB5 1 SER C 31  ? ALA C 34  ? SER Q 31  ALA Q 34  
AB5 2 THR C 123 ? ILE C 127 ? THR Q 123 ILE Q 127 
AB5 3 THR C 106 ? GLN C 111 ? THR Q 106 GLN Q 111 
AB5 4 THR C 118 ? PHE C 119 ? THR Q 118 PHE Q 119 
AB6 1 SER C 135 ? PHE C 139 ? SER Q 135 PHE Q 139 
AB6 2 ALA C 151 ? PHE C 160 ? ALA Q 151 PHE Q 160 
AB6 3 TYR C 194 ? LEU C 202 ? TYR Q 194 LEU Q 202 
AB6 4 SER C 180 ? VAL C 184 ? SER Q 180 VAL Q 184 
AB7 1 VAL C 167 ? GLN C 168 ? VAL Q 167 GLN Q 168 
AB7 2 VAL C 212 ? VAL C 217 ? VAL Q 212 VAL Q 217 
AB7 3 VAL C 226 ? ASN C 231 ? VAL Q 226 ASN Q 231 
AB8 1 GLU D 345 ? GLN D 346 ? GLU R 209 GLN R 210 
AB8 2 VAL D 359 ? CYS D 360 ? VAL R 223 CYS R 224 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O TYR A 133 ? O TYR B 112 N VAL A 61  ? N VAL B 40  
AA1 2 3 O VAL A 60  ? O VAL B 39  N TYR A 41  ? N TYR B 20  
AA1 3 4 O LEU A 42  ? O LEU B 21  N PHE A 29  ? N PHE B 8   
AA1 4 5 N VAL A 28  ? N VAL B 7   O SEP D 549 ? O SEP R 410 
AA2 1 2 N PHE A 47  ? N PHE B 26  O ARG A 189 ? O ARG B 168 
AA2 2 3 O LEU A 186 ? O LEU B 165 N VAL A 166 ? N VAL B 145 
AA2 3 4 O LYS A 167 ? O LYS B 146 N THR A 76  ? N THR B 55  
AA2 4 5 N CYS A 79  ? N CYS B 58  O PHE A 100 ? O PHE B 79  
AA3 1 2 N THR A 148 ? N THR B 127 O LEU A 309 ? O LEU B 288 
AA4 1 2 N THR A 206 ? N THR B 185 O LEU A 219 ? O LEU B 198 
AA4 2 3 N HIS A 218 ? N HIS B 197 O THR A 241 ? O THR B 220 
AA4 3 4 N ILE A 234 ? N ILE B 213 O LEU A 294 ? O LEU B 273 
AA5 1 2 N TYR A 228 ? N TYR B 207 O THR A 370 ? O THR B 349 
AA5 2 3 O VAL A 365 ? O VAL B 344 N VAL A 345 ? N VAL B 324 
AA5 3 4 O LYS A 344 ? O LYS B 323 N SER A 254 ? N SER B 233 
AA5 4 5 N GLN A 257 ? N GLN B 236 O CYS A 271 ? O CYS B 250 
AA5 5 6 N LYS A 270 ? N LYS B 249 O GLN D 231 ? O GLN R 95  
AA6 1 2 N VAL B 28  ? N VAL D 28  O ALA B 46  ? O ALA D 46  
AA6 2 3 N LEU B 43  ? N LEU D 43  O LEU B 104 ? O LEU D 104 
AA6 3 4 O TYR B 103 ? O TYR D 103 N SER B 94  ? N SER D 94  
AA7 1 2 O TYR B 82  ? O TYR D 82  N SER B 73  ? N SER D 73  
AA7 2 3 O VAL B 71  ? O VAL D 71  N TRP B 59  ? N TRP D 59  
AA7 3 4 N VAL B 60  ? N VAL D 60  O TYR B 118 ? O TYR D 118 
AA7 4 5 N ARG B 121 ? N ARG D 121 O TYR B 132 ? O TYR D 132 
AA8 1 2 O TYR B 82  ? O TYR D 82  N SER B 73  ? N SER D 73  
AA8 2 3 O VAL B 71  ? O VAL D 71  N TRP B 59  ? N TRP D 59  
AA8 3 4 N VAL B 60  ? N VAL D 60  O TYR B 118 ? O TYR D 118 
AA8 4 5 N ALA B 115 ? N ALA D 115 O VAL B 139 ? O VAL D 139 
AA9 1 2 N PHE B 152 ? N PHE D 152 O LEU B 171 ? O LEU D 171 
AA9 2 3 N ALA B 166 ? N ALA D 166 O VAL B 214 ? O VAL D 214 
AA9 3 4 O VAL B 211 ? O VAL D 211 N HIS B 194 ? N HIS D 194 
AB1 1 2 N PHE B 152 ? N PHE D 152 O LEU B 171 ? O LEU D 171 
AB1 2 3 N ALA B 166 ? N ALA D 166 O VAL B 214 ? O VAL D 214 
AB1 3 4 O SER B 207 ? O SER D 207 N VAL B 199 ? N VAL D 199 
AB2 1 2 N SER B 183 ? N SER D 183 O ASN B 227 ? O ASN D 227 
AB2 2 3 N CYS B 226 ? N CYS D 226 O LYS B 239 ? O LYS D 239 
AB3 1 2 N THR C 26  ? N THR Q 26  O ARG C 45  ? O ARG Q 45  
AB3 2 3 N ILE C 42  ? N ILE Q 42  O LEU C 94  ? O LEU Q 94  
AB3 3 4 O THR C 95  ? O THR Q 95  N SER C 84  ? N SER Q 84  
AB4 1 2 N LEU C 32  ? N LEU Q 32  O GLU C 126 ? O GLU Q 126 
AB4 2 3 O THR C 123 ? O THR Q 123 N TYR C 107 ? N TYR Q 107 
AB4 3 4 O TYR C 108 ? O TYR Q 108 N TYR C 57  ? N TYR Q 57  
AB4 4 5 N TRP C 56  ? N TRP Q 56  O LEU C 68  ? O LEU Q 68  
AB4 5 6 N TYR C 70  ? N TYR Q 70  O SER C 74  ? O SER Q 74  
AB5 1 2 N LEU C 32  ? N LEU Q 32  O GLU C 126 ? O GLU Q 126 
AB5 2 3 O THR C 123 ? O THR Q 123 N TYR C 107 ? N TYR Q 107 
AB5 3 4 N GLN C 111 ? N GLN Q 111 O THR C 118 ? O THR Q 118 
AB6 1 2 N SER C 135 ? N SER Q 135 O ASN C 158 ? O ASN Q 158 
AB6 2 3 N ALA C 151 ? N ALA Q 151 O LEU C 202 ? O LEU Q 202 
AB6 3 4 O THR C 199 ? O THR Q 199 N GLN C 181 ? N GLN Q 181 
AB7 1 2 N GLN C 168 ? N GLN Q 168 O GLU C 216 ? O GLU Q 216 
AB7 2 3 N TYR C 213 ? N TYR Q 213 O PHE C 230 ? O PHE Q 230 
AB8 1 2 N GLN D 346 ? N GLN R 210 O VAL D 359 ? O VAL R 223 
# 
_pdbx_entry_details.entry_id                   8ZYT 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   D PRO 153 ? ? OG Q SER 142 ? ? 2.13 
2 1 OD1 B ASP 203 ? ? OH B TYR 207 ? ? 2.14 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE B 30  ? ? 65.13   -60.62  
2  1 ARG B 75  ? ? 179.16  163.71  
3  1 PRO B 120 ? ? -67.90  -179.48 
4  1 LYS B 194 ? ? 56.80   72.68   
5  1 LEU B 242 ? ? -90.09  -62.24  
6  1 PHE B 267 ? ? -160.38 116.43  
7  1 ASN B 298 ? ? -68.23  -178.89 
8  1 GLU B 307 ? ? 58.93   16.99   
9  1 PRO B 360 ? ? -69.69  81.34   
10 1 SER D 76  ? ? 72.08   -8.40   
11 1 GLU D 112 ? ? -81.91  47.98   
12 1 TRP D 126 ? ? 71.49   43.94   
13 1 TYR D 127 ? ? -171.66 137.19  
14 1 ASP D 174 ? ? 60.29   65.46   
15 1 PRO D 177 ? ? -68.04  -173.76 
16 1 GLU D 178 ? ? -45.78  151.45  
17 1 SER Q 51  ? ? 58.44   -140.80 
18 1 LEU Q 68  ? ? -96.53  -63.48  
19 1 ALA Q 72  ? ? 72.01   -10.00  
20 1 PRO Q 116 ? ? -69.98  75.76   
21 1 ASN Q 159 ? ? 60.16   65.35   
22 1 ARG Q 163 ? ? 55.07   -139.74 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 D TPO 546 R TPO 407 ? THR 'modified residue' 
2 D SEP 548 R SEP 409 ? SER 'modified residue' 
3 D SEP 549 R SEP 410 ? SER 'modified residue' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZYT 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8ZYT 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.65 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               5006335 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'NTSR1-beta-arrestin1 complex' 
_em_entity_assembly.details              
'NTSR1 in complex with beat-arrestin1  and the arrestin-biased intracellular agonist SBI-553' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8ZYT 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8ZYT 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZYT 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B MET -20  ? A MET 1   
2   1 Y 1 B GLY -19  ? A GLY 2   
3   1 Y 1 B SER -18  ? A SER 3   
4   1 Y 1 B HIS -17  ? A HIS 4   
5   1 Y 1 B HIS -16  ? A HIS 5   
6   1 Y 1 B HIS -15  ? A HIS 6   
7   1 Y 1 B HIS -14  ? A HIS 7   
8   1 Y 1 B HIS -13  ? A HIS 8   
9   1 Y 1 B HIS -12  ? A HIS 9   
10  1 Y 1 B HIS -11  ? A HIS 10  
11  1 Y 1 B HIS -10  ? A HIS 11  
12  1 Y 1 B GLY -9   ? A GLY 12  
13  1 Y 1 B SER -8   ? A SER 13  
14  1 Y 1 B LEU -7   ? A LEU 14  
15  1 Y 1 B GLU -6   ? A GLU 15  
16  1 Y 1 B VAL -5   ? A VAL 16  
17  1 Y 1 B LEU -4   ? A LEU 17  
18  1 Y 1 B PHE -3   ? A PHE 18  
19  1 Y 1 B GLN -2   ? A GLN 19  
20  1 Y 1 B GLY -1   ? A GLY 20  
21  1 Y 1 B PRO 0    ? A PRO 21  
22  1 Y 1 B GLY 1    ? A GLY 22  
23  1 Y 1 B ASP 2    ? A ASP 23  
24  1 Y 1 B LYS 3    ? A LYS 24  
25  1 Y 1 B GLY 4    ? A GLY 25  
26  1 Y 1 B GLU 366  ? A GLU 387 
27  1 Y 1 B ASN 367  ? A ASN 388 
28  1 Y 1 B GLU 368  ? A GLU 389 
29  1 Y 1 B THR 369  ? A THR 390 
30  1 Y 1 B PRO 370  ? A PRO 391 
31  1 Y 1 B VAL 371  ? A VAL 392 
32  1 Y 1 B ASP 372  ? A ASP 393 
33  1 Y 1 B THR 373  ? A THR 394 
34  1 Y 1 B ASN 374  ? A ASN 395 
35  1 Y 1 B LEU 375  ? A LEU 396 
36  1 Y 1 B ILE 376  ? A ILE 397 
37  1 Y 1 B GLU 377  ? A GLU 398 
38  1 Y 1 B LEU 378  ? A LEU 399 
39  1 Y 1 B ASP 379  ? A ASP 400 
40  1 Y 1 B THR 380  ? A THR 401 
41  1 Y 1 B ASN 381  ? A ASN 402 
42  1 Y 1 D MET 1    ? B MET 1   
43  1 Y 1 D VAL 2    ? B VAL 2   
44  1 Y 1 D SER 3    ? B SER 3   
45  1 Y 1 D ALA 4    ? B ALA 4   
46  1 Y 1 D ILE 5    ? B ILE 5   
47  1 Y 1 D VAL 6    ? B VAL 6   
48  1 Y 1 D LEU 7    ? B LEU 7   
49  1 Y 1 D TYR 8    ? B TYR 8   
50  1 Y 1 D VAL 9    ? B VAL 9   
51  1 Y 1 D LEU 10   ? B LEU 10  
52  1 Y 1 D LEU 11   ? B LEU 11  
53  1 Y 1 D ALA 12   ? B ALA 12  
54  1 Y 1 D ALA 13   ? B ALA 13  
55  1 Y 1 D ALA 14   ? B ALA 14  
56  1 Y 1 D ALA 15   ? B ALA 15  
57  1 Y 1 D HIS 16   ? B HIS 16  
58  1 Y 1 D SER 17   ? B SER 17  
59  1 Y 1 D ALA 18   ? B ALA 18  
60  1 Y 1 D PHE 19   ? B PHE 19  
61  1 Y 1 D ALA 20   ? B ALA 20  
62  1 Y 1 D GLU 21   ? B GLU 21  
63  1 Y 1 D ILE 22   ? B ILE 22  
64  1 Y 1 D SER 23   ? B SER 23  
65  1 Y 1 D SER 245  ? B SER 245 
66  1 Y 1 D CYS 246  ? B CYS 246 
67  1 Y 1 D ASP 247  ? B ASP 247 
68  1 Y 1 D LYS 248  ? B LYS 248 
69  1 Y 1 D THR 249  ? B THR 249 
70  1 Y 1 D ALA 250  ? B ALA 250 
71  1 Y 1 D ALA 251  ? B ALA 251 
72  1 Y 1 D ALA 252  ? B ALA 252 
73  1 Y 1 D HIS 253  ? B HIS 253 
74  1 Y 1 D HIS 254  ? B HIS 254 
75  1 Y 1 D HIS 255  ? B HIS 255 
76  1 Y 1 D HIS 256  ? B HIS 256 
77  1 Y 1 D HIS 257  ? B HIS 257 
78  1 Y 1 D HIS 258  ? B HIS 258 
79  1 Y 1 D HIS 259  ? B HIS 259 
80  1 Y 1 D HIS 260  ? B HIS 260 
81  1 Y 1 Q MET 1    ? C MET 1   
82  1 Y 1 Q VAL 2    ? C VAL 2   
83  1 Y 1 Q SER 3    ? C SER 3   
84  1 Y 1 Q ALA 4    ? C ALA 4   
85  1 Y 1 Q ILE 5    ? C ILE 5   
86  1 Y 1 Q VAL 6    ? C VAL 6   
87  1 Y 1 Q LEU 7    ? C LEU 7   
88  1 Y 1 Q TYR 8    ? C TYR 8   
89  1 Y 1 Q VAL 9    ? C VAL 9   
90  1 Y 1 Q LEU 10   ? C LEU 10  
91  1 Y 1 Q LEU 11   ? C LEU 11  
92  1 Y 1 Q ALA 12   ? C ALA 12  
93  1 Y 1 Q ALA 13   ? C ALA 13  
94  1 Y 1 Q ALA 14   ? C ALA 14  
95  1 Y 1 Q ALA 15   ? C ALA 15  
96  1 Y 1 Q HIS 16   ? C HIS 16  
97  1 Y 1 Q SER 17   ? C SER 17  
98  1 Y 1 Q ALA 18   ? C ALA 18  
99  1 Y 1 Q PHE 19   ? C PHE 19  
100 1 Y 1 R MET -135 ? D MET 1   
101 1 Y 1 R LYS -134 ? D LYS 2   
102 1 Y 1 R THR -133 ? D THR 3   
103 1 Y 1 R ILE -132 ? D ILE 4   
104 1 Y 1 R ILE -131 ? D ILE 5   
105 1 Y 1 R ALA -130 ? D ALA 6   
106 1 Y 1 R LEU -129 ? D LEU 7   
107 1 Y 1 R SER -128 ? D SER 8   
108 1 Y 1 R TYR -127 ? D TYR 9   
109 1 Y 1 R ILE -126 ? D ILE 10  
110 1 Y 1 R PHE -125 ? D PHE 11  
111 1 Y 1 R CYS -124 ? D CYS 12  
112 1 Y 1 R LEU -123 ? D LEU 13  
113 1 Y 1 R VAL -122 ? D VAL 14  
114 1 Y 1 R PHE -121 ? D PHE 15  
115 1 Y 1 R ALA -120 ? D ALA 16  
116 1 Y 1 R GLY -119 ? D GLY 17  
117 1 Y 1 R SER -118 ? D SER 18  
118 1 Y 1 R ALA -117 ? D ALA 19  
119 1 Y 1 R ASP -116 ? D ASP 20  
120 1 Y 1 R LEU -115 ? D LEU 21  
121 1 Y 1 R GLU -114 ? D GLU 22  
122 1 Y 1 R ASP -113 ? D ASP 23  
123 1 Y 1 R ASN -112 ? D ASN 24  
124 1 Y 1 R TRP -111 ? D TRP 25  
125 1 Y 1 R GLU -110 ? D GLU 26  
126 1 Y 1 R THR -109 ? D THR 27  
127 1 Y 1 R LEU -108 ? D LEU 28  
128 1 Y 1 R ASN -107 ? D ASN 29  
129 1 Y 1 R ASP -106 ? D ASP 30  
130 1 Y 1 R ASN -105 ? D ASN 31  
131 1 Y 1 R LEU -104 ? D LEU 32  
132 1 Y 1 R LYS -103 ? D LYS 33  
133 1 Y 1 R VAL -102 ? D VAL 34  
134 1 Y 1 R ILE -101 ? D ILE 35  
135 1 Y 1 R GLU -100 ? D GLU 36  
136 1 Y 1 R LYS -99  ? D LYS 37  
137 1 Y 1 R ALA -98  ? D ALA 38  
138 1 Y 1 R ASP -97  ? D ASP 39  
139 1 Y 1 R ASN -96  ? D ASN 40  
140 1 Y 1 R ALA -95  ? D ALA 41  
141 1 Y 1 R ALA -94  ? D ALA 42  
142 1 Y 1 R GLN -93  ? D GLN 43  
143 1 Y 1 R VAL -92  ? D VAL 44  
144 1 Y 1 R LYS -91  ? D LYS 45  
145 1 Y 1 R ASP -90  ? D ASP 46  
146 1 Y 1 R ALA -89  ? D ALA 47  
147 1 Y 1 R LEU -88  ? D LEU 48  
148 1 Y 1 R THR -87  ? D THR 49  
149 1 Y 1 R LYS -86  ? D LYS 50  
150 1 Y 1 R MET -85  ? D MET 51  
151 1 Y 1 R ARG -84  ? D ARG 52  
152 1 Y 1 R ALA -83  ? D ALA 53  
153 1 Y 1 R ALA -82  ? D ALA 54  
154 1 Y 1 R ALA -81  ? D ALA 55  
155 1 Y 1 R LEU -80  ? D LEU 56  
156 1 Y 1 R ASP -79  ? D ASP 57  
157 1 Y 1 R ALA -78  ? D ALA 58  
158 1 Y 1 R GLN -77  ? D GLN 59  
159 1 Y 1 R LYS -76  ? D LYS 60  
160 1 Y 1 R ALA -75  ? D ALA 61  
161 1 Y 1 R THR -74  ? D THR 62  
162 1 Y 1 R PRO -73  ? D PRO 63  
163 1 Y 1 R PRO -72  ? D PRO 64  
164 1 Y 1 R LYS -71  ? D LYS 65  
165 1 Y 1 R LEU -70  ? D LEU 66  
166 1 Y 1 R GLU -69  ? D GLU 67  
167 1 Y 1 R ASP -68  ? D ASP 68  
168 1 Y 1 R LYS -67  ? D LYS 69  
169 1 Y 1 R SER -66  ? D SER 70  
170 1 Y 1 R PRO -65  ? D PRO 71  
171 1 Y 1 R ASP -64  ? D ASP 72  
172 1 Y 1 R SER -63  ? D SER 73  
173 1 Y 1 R PRO -62  ? D PRO 74  
174 1 Y 1 R GLU -61  ? D GLU 75  
175 1 Y 1 R MET -60  ? D MET 76  
176 1 Y 1 R LYS -59  ? D LYS 77  
177 1 Y 1 R ASP -58  ? D ASP 78  
178 1 Y 1 R PHE -57  ? D PHE 79  
179 1 Y 1 R ARG -56  ? D ARG 80  
180 1 Y 1 R HIS -55  ? D HIS 81  
181 1 Y 1 R GLY -54  ? D GLY 82  
182 1 Y 1 R PHE -53  ? D PHE 83  
183 1 Y 1 R ASP -52  ? D ASP 84  
184 1 Y 1 R ILE -51  ? D ILE 85  
185 1 Y 1 R LEU -50  ? D LEU 86  
186 1 Y 1 R VAL -49  ? D VAL 87  
187 1 Y 1 R GLY -48  ? D GLY 88  
188 1 Y 1 R GLN -47  ? D GLN 89  
189 1 Y 1 R ILE -46  ? D ILE 90  
190 1 Y 1 R ASP -45  ? D ASP 91  
191 1 Y 1 R ASP -44  ? D ASP 92  
192 1 Y 1 R ALA -43  ? D ALA 93  
193 1 Y 1 R LEU -42  ? D LEU 94  
194 1 Y 1 R LYS -41  ? D LYS 95  
195 1 Y 1 R LEU -40  ? D LEU 96  
196 1 Y 1 R ALA -39  ? D ALA 97  
197 1 Y 1 R ASN -38  ? D ASN 98  
198 1 Y 1 R GLU -37  ? D GLU 99  
199 1 Y 1 R GLY -36  ? D GLY 100 
200 1 Y 1 R LYS -35  ? D LYS 101 
201 1 Y 1 R VAL -34  ? D VAL 102 
202 1 Y 1 R LYS -33  ? D LYS 103 
203 1 Y 1 R GLU -32  ? D GLU 104 
204 1 Y 1 R ALA -31  ? D ALA 105 
205 1 Y 1 R GLN -30  ? D GLN 106 
206 1 Y 1 R ALA -29  ? D ALA 107 
207 1 Y 1 R ALA -28  ? D ALA 108 
208 1 Y 1 R ALA -27  ? D ALA 109 
209 1 Y 1 R GLU -26  ? D GLU 110 
210 1 Y 1 R GLN -25  ? D GLN 111 
211 1 Y 1 R LEU -24  ? D LEU 112 
212 1 Y 1 R LYS -23  ? D LYS 113 
213 1 Y 1 R THR -22  ? D THR 114 
214 1 Y 1 R THR -21  ? D THR 115 
215 1 Y 1 R ARG -20  ? D ARG 116 
216 1 Y 1 R ASN -19  ? D ASN 117 
217 1 Y 1 R ALA -18  ? D ALA 118 
218 1 Y 1 R TYR -17  ? D TYR 119 
219 1 Y 1 R ILE -16  ? D ILE 120 
220 1 Y 1 R GLN -15  ? D GLN 121 
221 1 Y 1 R LYS -14  ? D LYS 122 
222 1 Y 1 R TYR -13  ? D TYR 123 
223 1 Y 1 R LEU -12  ? D LEU 124 
224 1 Y 1 R ALA -11  ? D ALA 125 
225 1 Y 1 R SER -10  ? D SER 126 
226 1 Y 1 R GLY -9   ? D GLY 127 
227 1 Y 1 R SER -8   ? D SER 128 
228 1 Y 1 R LEU -7   ? D LEU 129 
229 1 Y 1 R GLU -6   ? D GLU 130 
230 1 Y 1 R VAL -5   ? D VAL 131 
231 1 Y 1 R LEU -4   ? D LEU 132 
232 1 Y 1 R PHE -3   ? D PHE 133 
233 1 Y 1 R GLN -2   ? D GLN 134 
234 1 Y 1 R GLY -1   ? D GLY 135 
235 1 Y 1 R PRO 0    ? D PRO 136 
236 1 Y 1 R MET 1    ? D MET 137 
237 1 Y 1 R ARG 2    ? D ARG 138 
238 1 Y 1 R LEU 3    ? D LEU 139 
239 1 Y 1 R ASN 4    ? D ASN 140 
240 1 Y 1 R SER 5    ? D SER 141 
241 1 Y 1 R SER 6    ? D SER 142 
242 1 Y 1 R ALA 7    ? D ALA 143 
243 1 Y 1 R PRO 8    ? D PRO 144 
244 1 Y 1 R GLY 9    ? D GLY 145 
245 1 Y 1 R THR 10   ? D THR 146 
246 1 Y 1 R PRO 11   ? D PRO 147 
247 1 Y 1 R GLY 12   ? D GLY 148 
248 1 Y 1 R THR 13   ? D THR 149 
249 1 Y 1 R PRO 14   ? D PRO 150 
250 1 Y 1 R ALA 15   ? D ALA 151 
251 1 Y 1 R ALA 16   ? D ALA 152 
252 1 Y 1 R ASP 17   ? D ASP 153 
253 1 Y 1 R PRO 18   ? D PRO 154 
254 1 Y 1 R PHE 19   ? D PHE 155 
255 1 Y 1 R GLN 20   ? D GLN 156 
256 1 Y 1 R ARG 21   ? D ARG 157 
257 1 Y 1 R ALA 22   ? D ALA 158 
258 1 Y 1 R GLN 23   ? D GLN 159 
259 1 Y 1 R ALA 24   ? D ALA 160 
260 1 Y 1 R GLY 25   ? D GLY 161 
261 1 Y 1 R LEU 26   ? D LEU 162 
262 1 Y 1 R GLU 27   ? D GLU 163 
263 1 Y 1 R GLU 28   ? D GLU 164 
264 1 Y 1 R ALA 29   ? D ALA 165 
265 1 Y 1 R LEU 30   ? D LEU 166 
266 1 Y 1 R LEU 31   ? D LEU 167 
267 1 Y 1 R ALA 32   ? D ALA 168 
268 1 Y 1 R PRO 33   ? D PRO 169 
269 1 Y 1 R GLY 34   ? D GLY 170 
270 1 Y 1 R PHE 35   ? D PHE 171 
271 1 Y 1 R GLY 36   ? D GLY 172 
272 1 Y 1 R ASN 37   ? D ASN 173 
273 1 Y 1 R ALA 38   ? D ALA 174 
274 1 Y 1 R SER 39   ? D SER 175 
275 1 Y 1 R GLY 40   ? D GLY 176 
276 1 Y 1 R ASN 41   ? D ASN 177 
277 1 Y 1 R ALA 42   ? D ALA 178 
278 1 Y 1 R SER 43   ? D SER 179 
279 1 Y 1 R GLU 44   ? D GLU 180 
280 1 Y 1 R ARG 45   ? D ARG 181 
281 1 Y 1 R VAL 46   ? D VAL 182 
282 1 Y 1 R LEU 47   ? D LEU 183 
283 1 Y 1 R ALA 48   ? D ALA 184 
284 1 Y 1 R ALA 49   ? D ALA 185 
285 1 Y 1 R PRO 50   ? D PRO 186 
286 1 Y 1 R SER 51   ? D SER 187 
287 1 Y 1 R SER 52   ? D SER 188 
288 1 Y 1 R GLU 53   ? D GLU 189 
289 1 Y 1 R LEU 54   ? D LEU 190 
290 1 Y 1 R ASP 55   ? D ASP 191 
291 1 Y 1 R ARG 268  ? D ARG 404 
292 1 Y 1 R GLN 269  ? D GLN 405 
293 1 Y 1 R ALA 270  ? D ALA 406 
294 1 Y 1 R ALA 271  ? D ALA 407 
295 1 Y 1 R GLU 272  ? D GLU 408 
296 1 Y 1 R GLN 273  ? D GLN 409 
297 1 Y 1 R GLY 274  ? D GLY 410 
298 1 Y 1 R GLN 275  ? D GLN 411 
299 1 Y 1 R VAL 276  ? D VAL 412 
300 1 Y 1 R CYS 277  ? D CYS 413 
301 1 Y 1 R THR 278  ? D THR 414 
302 1 Y 1 R VAL 279  ? D VAL 415 
303 1 Y 1 R GLY 280  ? D GLY 416 
304 1 Y 1 R GLY 281  ? D GLY 417 
305 1 Y 1 R GLU 282  ? D GLU 418 
306 1 Y 1 R HIS 283  ? D HIS 419 
307 1 Y 1 R SER 284  ? D SER 420 
308 1 Y 1 R THR 285  ? D THR 421 
309 1 Y 1 R PHE 286  ? D PHE 422 
310 1 Y 1 R SER 287  ? D SER 423 
311 1 Y 1 R MET 288  ? D MET 424 
312 1 Y 1 R ALA 289  ? D ALA 425 
313 1 Y 1 R ILE 290  ? D ILE 426 
314 1 Y 1 R GLU 291  ? D GLU 427 
315 1 Y 1 R PRO 292  ? D PRO 428 
316 1 Y 1 R GLY 293  ? D GLY 429 
317 1 Y 1 R ARG 294  ? D ARG 430 
318 1 Y 1 R VAL 295  ? D VAL 431 
319 1 Y 1 R GLN 296  ? D GLN 432 
320 1 Y 1 R ALA 297  ? D ALA 433 
321 1 Y 1 R LEU 298  ? D LEU 434 
322 1 Y 1 R CYS 380  A D CYS 517 
323 1 Y 1 R LEU 380  B D LEU 518 
324 1 Y 1 R CYS 380  C D CYS 519 
325 1 Y 1 R PRO 380  D D PRO 520 
326 1 Y 1 R VAL 380  E D VAL 521 
327 1 Y 1 R TRP 380  F D TRP 522 
328 1 Y 1 R ARG 380  G D ARG 523 
329 1 Y 1 R ARG 380  H D ARG 524 
330 1 Y 1 R ARG 380  I D ARG 525 
331 1 Y 1 R ARG 380  J D ARG 526 
332 1 Y 1 R LYS 380  K D LYS 527 
333 1 Y 1 R ARG 380  L D ARG 528 
334 1 Y 1 R PRO 380  M D PRO 529 
335 1 Y 1 R CYS 380  N D CYS 530 
336 1 Y 1 R PHE 380  O D PHE 531 
337 1 Y 1 R ASN 380  P D ASN 532 
338 1 Y 1 R ALA 380  Q D ALA 533 
339 1 Y 1 R PHE 380  R D PHE 534 
340 1 Y 1 R SER 380  S D SER 535 
341 1 Y 1 R ARG 380  T D ARG 536 
342 1 Y 1 R LYS 380  U D LYS 537 
343 1 Y 1 R CYS 380  V D CYS 538 
344 1 Y 1 R ASP 380  W D ASP 539 
345 1 Y 1 R SEP 380  X D SEP 540 
346 1 Y 1 R VAL 380  Y D VAL 541 
347 1 Y 1 R SEP 380  Z D SEP 542 
348 1 Y 1 R SEP 381  A D SEP 543 
349 1 Y 1 R THR 413  ? D THR 552 
350 1 Y 1 R ARG 414  ? D ARG 553 
351 1 Y 1 R GLU 415  ? D GLU 554 
352 1 Y 1 R THR 416  ? D THR 555 
353 1 Y 1 R LEU 417  ? D LEU 556 
354 1 Y 1 R TYR 418  ? D TYR 557 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PIO C1   C N R 270 
PIO O1   O N N 271 
PIO P1   P N N 272 
PIO C2   C N R 273 
PIO O2   O N N 274 
PIO C3   C N S 275 
PIO O3   O N N 276 
PIO C4   C N R 277 
PIO O4   O N N 278 
PIO P4   P N N 279 
PIO C5   C N R 280 
PIO O5   O N N 281 
PIO P5   P N N 282 
PIO C6   C N S 283 
PIO O6   O N N 284 
PIO O11  O N N 285 
PIO O12  O N N 286 
PIO O13  O N N 287 
PIO C1A  C N N 288 
PIO O1A  O N N 289 
PIO C1B  C N N 290 
PIO O1B  O N N 291 
PIO C1C  C N N 292 
PIO C2A  C N N 293 
PIO C2B  C N N 294 
PIO C2C  C N R 295 
PIO O2C  O N N 296 
PIO C3A  C N N 297 
PIO C3B  C N N 298 
PIO C3C  C N N 299 
PIO O3C  O N N 300 
PIO O41  O N N 301 
PIO O42  O N N 302 
PIO O43  O N N 303 
PIO C4A  C N N 304 
PIO C4B  C N N 305 
PIO O51  O N N 306 
PIO O52  O N N 307 
PIO O53  O N N 308 
PIO C5A  C N N 309 
PIO C5B  C N N 310 
PIO C6A  C N N 311 
PIO C6B  C N N 312 
PIO C7A  C N N 313 
PIO C7B  C N N 314 
PIO C8A  C N N 315 
PIO C8B  C N N 316 
PIO H1   H N N 317 
PIO H2   H N N 318 
PIO H3   H N N 319 
PIO H4   H N N 320 
PIO H5   H N N 321 
PIO H6   H N N 322 
PIO H1C  H N N 323 
PIO H1CA H N N 324 
PIO H3C  H N N 325 
PIO H3CA H N N 326 
PIO H2A  H N N 327 
PIO H3A  H N N 328 
PIO H4A  H N N 329 
PIO H5A  H N N 330 
PIO H6A  H N N 331 
PIO H7A  H N N 332 
PIO H8A  H N N 333 
PIO H2AA H N N 334 
PIO H3AA H N N 335 
PIO H4AA H N N 336 
PIO H5AA H N N 337 
PIO H6AA H N N 338 
PIO H7AA H N N 339 
PIO H8AA H N N 340 
PIO H8AB H N N 341 
PIO H2B  H N N 342 
PIO H3B  H N N 343 
PIO H4B  H N N 344 
PIO H5B  H N N 345 
PIO H6B  H N N 346 
PIO H7B  H N N 347 
PIO H8B  H N N 348 
PIO H2BA H N N 349 
PIO H3BA H N N 350 
PIO H4BA H N N 351 
PIO H5BA H N N 352 
PIO H6BA H N N 353 
PIO H7BA H N N 354 
PIO H8BA H N N 355 
PIO H8BB H N N 356 
PIO H2C  H N N 357 
PIO HO2  H N N 358 
PIO HO3  H N N 359 
PIO HO6  H N N 360 
PIO H41  H N N 361 
PIO H43  H N N 362 
PIO H51  H N N 363 
PIO H52  H N N 364 
PIO H11  H N N 365 
PRO N    N N N 366 
PRO CA   C N S 367 
PRO C    C N N 368 
PRO O    O N N 369 
PRO CB   C N N 370 
PRO CG   C N N 371 
PRO CD   C N N 372 
PRO OXT  O N N 373 
PRO H    H N N 374 
PRO HA   H N N 375 
PRO HB2  H N N 376 
PRO HB3  H N N 377 
PRO HG2  H N N 378 
PRO HG3  H N N 379 
PRO HD2  H N N 380 
PRO HD3  H N N 381 
PRO HXT  H N N 382 
SEP N    N N N 383 
SEP CA   C N S 384 
SEP CB   C N N 385 
SEP OG   O N N 386 
SEP C    C N N 387 
SEP O    O N N 388 
SEP OXT  O N N 389 
SEP P    P N N 390 
SEP O1P  O N N 391 
SEP O2P  O N N 392 
SEP O3P  O N N 393 
SEP H    H N N 394 
SEP H2   H N N 395 
SEP HA   H N N 396 
SEP HB2  H N N 397 
SEP HB3  H N N 398 
SEP HXT  H N N 399 
SEP HOP2 H N N 400 
SEP HOP3 H N N 401 
SER N    N N N 402 
SER CA   C N S 403 
SER C    C N N 404 
SER O    O N N 405 
SER CB   C N N 406 
SER OG   O N N 407 
SER OXT  O N N 408 
SER H    H N N 409 
SER H2   H N N 410 
SER HA   H N N 411 
SER HB2  H N N 412 
SER HB3  H N N 413 
SER HG   H N N 414 
SER HXT  H N N 415 
SRW C1   C N N 416 
SRW O1   O N N 417 
SRW C2   C Y N 418 
SRW C3   C Y N 419 
SRW C4   C Y N 420 
SRW C5   C Y N 421 
SRW C6   C Y N 422 
SRW C7   C Y N 423 
SRW C8   C N N 424 
SRW C9   C N N 425 
SRW C10  C N N 426 
SRW N1   N N N 427 
SRW C11  C N N 428 
SRW C12  C N N 429 
SRW C13  C Y N 430 
SRW N2   N Y N 431 
SRW C14  C Y N 432 
SRW N3   N Y N 433 
SRW C15  C Y N 434 
SRW C16  C Y N 435 
SRW C17  C Y N 436 
SRW C18  C Y N 437 
SRW C19  C Y N 438 
SRW C20  C Y N 439 
SRW N4   N N N 440 
SRW C21  C N N 441 
SRW C22  C N N 442 
SRW C23  C N N 443 
SRW O2   O N N 444 
SRW C24  C N N 445 
SRW F1   F N N 446 
SRW C25  C N N 447 
SRW C26  C N N 448 
SRW H1   H N N 449 
SRW H2   H N N 450 
SRW H3   H N N 451 
SRW H4   H N N 452 
SRW H5   H N N 453 
SRW H6   H N N 454 
SRW H7   H N N 455 
SRW H8   H N N 456 
SRW H9   H N N 457 
SRW H10  H N N 458 
SRW H11  H N N 459 
SRW H12  H N N 460 
SRW H13  H N N 461 
SRW H14  H N N 462 
SRW H15  H N N 463 
SRW H16  H N N 464 
SRW H17  H N N 465 
SRW H18  H N N 466 
SRW H19  H N N 467 
SRW H20  H N N 468 
SRW H21  H N N 469 
SRW H22  H N N 470 
SRW H23  H N N 471 
SRW H24  H N N 472 
SRW H25  H N N 473 
SRW H26  H N N 474 
SRW H27  H N N 475 
SRW H28  H N N 476 
SRW H29  H N N 477 
SRW H30  H N N 478 
SRW H31  H N N 479 
THR N    N N N 480 
THR CA   C N S 481 
THR C    C N N 482 
THR O    O N N 483 
THR CB   C N R 484 
THR OG1  O N N 485 
THR CG2  C N N 486 
THR OXT  O N N 487 
THR H    H N N 488 
THR H2   H N N 489 
THR HA   H N N 490 
THR HB   H N N 491 
THR HG1  H N N 492 
THR HG21 H N N 493 
THR HG22 H N N 494 
THR HG23 H N N 495 
THR HXT  H N N 496 
TPO N    N N N 497 
TPO CA   C N S 498 
TPO CB   C N R 499 
TPO CG2  C N N 500 
TPO OG1  O N N 501 
TPO P    P N N 502 
TPO O1P  O N N 503 
TPO O2P  O N N 504 
TPO O3P  O N N 505 
TPO C    C N N 506 
TPO O    O N N 507 
TPO OXT  O N N 508 
TPO H    H N N 509 
TPO H2   H N N 510 
TPO HA   H N N 511 
TPO HB   H N N 512 
TPO HG21 H N N 513 
TPO HG22 H N N 514 
TPO HG23 H N N 515 
TPO HOP2 H N N 516 
TPO HOP3 H N N 517 
TPO HXT  H N N 518 
TRP N    N N N 519 
TRP CA   C N S 520 
TRP C    C N N 521 
TRP O    O N N 522 
TRP CB   C N N 523 
TRP CG   C Y N 524 
TRP CD1  C Y N 525 
TRP CD2  C Y N 526 
TRP NE1  N Y N 527 
TRP CE2  C Y N 528 
TRP CE3  C Y N 529 
TRP CZ2  C Y N 530 
TRP CZ3  C Y N 531 
TRP CH2  C Y N 532 
TRP OXT  O N N 533 
TRP H    H N N 534 
TRP H2   H N N 535 
TRP HA   H N N 536 
TRP HB2  H N N 537 
TRP HB3  H N N 538 
TRP HD1  H N N 539 
TRP HE1  H N N 540 
TRP HE3  H N N 541 
TRP HZ2  H N N 542 
TRP HZ3  H N N 543 
TRP HH2  H N N 544 
TRP HXT  H N N 545 
TYR N    N N N 546 
TYR CA   C N S 547 
TYR C    C N N 548 
TYR O    O N N 549 
TYR CB   C N N 550 
TYR CG   C Y N 551 
TYR CD1  C Y N 552 
TYR CD2  C Y N 553 
TYR CE1  C Y N 554 
TYR CE2  C Y N 555 
TYR CZ   C Y N 556 
TYR OH   O N N 557 
TYR OXT  O N N 558 
TYR H    H N N 559 
TYR H2   H N N 560 
TYR HA   H N N 561 
TYR HB2  H N N 562 
TYR HB3  H N N 563 
TYR HD1  H N N 564 
TYR HD2  H N N 565 
TYR HE1  H N N 566 
TYR HE2  H N N 567 
TYR HH   H N N 568 
TYR HXT  H N N 569 
VAL N    N N N 570 
VAL CA   C N S 571 
VAL C    C N N 572 
VAL O    O N N 573 
VAL CB   C N N 574 
VAL CG1  C N N 575 
VAL CG2  C N N 576 
VAL OXT  O N N 577 
VAL H    H N N 578 
VAL H2   H N N 579 
VAL HA   H N N 580 
VAL HB   H N N 581 
VAL HG11 H N N 582 
VAL HG12 H N N 583 
VAL HG13 H N N 584 
VAL HG21 H N N 585 
VAL HG22 H N N 586 
VAL HG23 H N N 587 
VAL HXT  H N N 588 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PIO C1  O1   sing N N 258 
PIO C1  C2   sing N N 259 
PIO C1  C6   sing N N 260 
PIO C1  H1   sing N N 261 
PIO O1  P1   sing N N 262 
PIO P1  O11  sing N N 263 
PIO O11 H11  sing N N 264 
PIO P1  O12  doub N N 265 
PIO P1  O13  sing N N 266 
PIO C2  O2   sing N N 267 
PIO C2  C3   sing N N 268 
PIO C2  H2   sing N N 269 
PIO O2  HO2  sing N N 270 
PIO C3  O3   sing N N 271 
PIO C3  C4   sing N N 272 
PIO C3  H3   sing N N 273 
PIO O3  HO3  sing N N 274 
PIO C4  O4   sing N N 275 
PIO C4  C5   sing N N 276 
PIO C4  H4   sing N N 277 
PIO O4  P4   sing N N 278 
PIO P4  O41  sing N N 279 
PIO O41 H41  sing N N 280 
PIO P4  O42  doub N N 281 
PIO P4  O43  sing N N 282 
PIO O43 H43  sing N N 283 
PIO C5  O5   sing N N 284 
PIO C5  C6   sing N N 285 
PIO C5  H5   sing N N 286 
PIO O5  P5   sing N N 287 
PIO P5  O51  sing N N 288 
PIO O51 H51  sing N N 289 
PIO P5  O52  sing N N 290 
PIO O52 H52  sing N N 291 
PIO P5  O53  doub N N 292 
PIO C6  O6   sing N N 293 
PIO C6  H6   sing N N 294 
PIO O6  HO6  sing N N 295 
PIO O13 C1C  sing N N 296 
PIO C1A O1A  doub N N 297 
PIO C1A C2A  sing N N 298 
PIO C1A O2C  sing N N 299 
PIO C1B O1B  doub N N 300 
PIO C1B C2B  sing N N 301 
PIO C1B O3C  sing N N 302 
PIO C1C C2C  sing N N 303 
PIO C1C H1C  sing N N 304 
PIO C1C H1CA sing N N 305 
PIO C2A C3A  sing N N 306 
PIO C2A H2A  sing N N 307 
PIO C2A H2AA sing N N 308 
PIO C2B C3B  sing N N 309 
PIO C2B H2B  sing N N 310 
PIO C2B H2BA sing N N 311 
PIO C2C O2C  sing N N 312 
PIO C2C C3C  sing N N 313 
PIO C2C H2C  sing N N 314 
PIO C3A C4A  sing N N 315 
PIO C3A H3A  sing N N 316 
PIO C3A H3AA sing N N 317 
PIO C3B C4B  sing N N 318 
PIO C3B H3B  sing N N 319 
PIO C3B H3BA sing N N 320 
PIO C3C O3C  sing N N 321 
PIO C3C H3C  sing N N 322 
PIO C3C H3CA sing N N 323 
PIO C4A C5A  sing N N 324 
PIO C4A H4A  sing N N 325 
PIO C4A H4AA sing N N 326 
PIO C4B C5B  sing N N 327 
PIO C4B H4B  sing N N 328 
PIO C4B H4BA sing N N 329 
PIO C5A C6A  sing N N 330 
PIO C5A H5A  sing N N 331 
PIO C5A H5AA sing N N 332 
PIO C5B C6B  sing N N 333 
PIO C5B H5B  sing N N 334 
PIO C5B H5BA sing N N 335 
PIO C6A C7A  sing N N 336 
PIO C6A H6A  sing N N 337 
PIO C6A H6AA sing N N 338 
PIO C6B C7B  sing N N 339 
PIO C6B H6B  sing N N 340 
PIO C6B H6BA sing N N 341 
PIO C7A C8A  sing N N 342 
PIO C7A H7A  sing N N 343 
PIO C7A H7AA sing N N 344 
PIO C7B C8B  sing N N 345 
PIO C7B H7B  sing N N 346 
PIO C7B H7BA sing N N 347 
PIO C8A H8A  sing N N 348 
PIO C8A H8AA sing N N 349 
PIO C8A H8AB sing N N 350 
PIO C8B H8B  sing N N 351 
PIO C8B H8BA sing N N 352 
PIO C8B H8BB sing N N 353 
PRO N   CA   sing N N 354 
PRO N   CD   sing N N 355 
PRO N   H    sing N N 356 
PRO CA  C    sing N N 357 
PRO CA  CB   sing N N 358 
PRO CA  HA   sing N N 359 
PRO C   O    doub N N 360 
PRO C   OXT  sing N N 361 
PRO CB  CG   sing N N 362 
PRO CB  HB2  sing N N 363 
PRO CB  HB3  sing N N 364 
PRO CG  CD   sing N N 365 
PRO CG  HG2  sing N N 366 
PRO CG  HG3  sing N N 367 
PRO CD  HD2  sing N N 368 
PRO CD  HD3  sing N N 369 
PRO OXT HXT  sing N N 370 
SEP N   CA   sing N N 371 
SEP N   H    sing N N 372 
SEP N   H2   sing N N 373 
SEP CA  CB   sing N N 374 
SEP CA  C    sing N N 375 
SEP CA  HA   sing N N 376 
SEP CB  OG   sing N N 377 
SEP CB  HB2  sing N N 378 
SEP CB  HB3  sing N N 379 
SEP OG  P    sing N N 380 
SEP C   O    doub N N 381 
SEP C   OXT  sing N N 382 
SEP OXT HXT  sing N N 383 
SEP P   O1P  doub N N 384 
SEP P   O2P  sing N N 385 
SEP P   O3P  sing N N 386 
SEP O2P HOP2 sing N N 387 
SEP O3P HOP3 sing N N 388 
SER N   CA   sing N N 389 
SER N   H    sing N N 390 
SER N   H2   sing N N 391 
SER CA  C    sing N N 392 
SER CA  CB   sing N N 393 
SER CA  HA   sing N N 394 
SER C   O    doub N N 395 
SER C   OXT  sing N N 396 
SER CB  OG   sing N N 397 
SER CB  HB2  sing N N 398 
SER CB  HB3  sing N N 399 
SER OG  HG   sing N N 400 
SER OXT HXT  sing N N 401 
SRW C6  C7   doub Y N 402 
SRW C6  C5   sing Y N 403 
SRW C7  C2   sing Y N 404 
SRW C5  C4   doub Y N 405 
SRW C2  O1   sing N N 406 
SRW C2  C3   doub Y N 407 
SRW C4  C3   sing Y N 408 
SRW O1  C1   sing N N 409 
SRW C3  C8   sing N N 410 
SRW C8  C9   sing N N 411 
SRW C8  C12  sing N N 412 
SRW C9  C10  sing N N 413 
SRW C12 C11  sing N N 414 
SRW C11 N1   sing N N 415 
SRW C10 N1   sing N N 416 
SRW N1  C13  sing N N 417 
SRW C26 C24  sing N N 418 
SRW C26 C25  sing N N 419 
SRW C13 N2   doub Y N 420 
SRW C13 C16  sing Y N 421 
SRW N2  C14  sing Y N 422 
SRW C21 N4   sing N N 423 
SRW C16 C17  doub Y N 424 
SRW C16 C15  sing Y N 425 
SRW C17 C18  sing Y N 426 
SRW C14 C24  sing N N 427 
SRW C14 N3   doub Y N 428 
SRW C24 C25  sing N N 429 
SRW C24 F1   sing N N 430 
SRW C15 N3   sing Y N 431 
SRW C15 C20  doub Y N 432 
SRW C18 N4   sing N N 433 
SRW C18 C19  doub Y N 434 
SRW N4  C22  sing N N 435 
SRW C20 C19  sing Y N 436 
SRW C22 C23  sing N N 437 
SRW C23 O2   sing N N 438 
SRW C1  H1   sing N N 439 
SRW C1  H2   sing N N 440 
SRW C1  H3   sing N N 441 
SRW C4  H4   sing N N 442 
SRW C5  H5   sing N N 443 
SRW C6  H6   sing N N 444 
SRW C7  H7   sing N N 445 
SRW C8  H8   sing N N 446 
SRW C9  H9   sing N N 447 
SRW C9  H10  sing N N 448 
SRW C10 H11  sing N N 449 
SRW C10 H12  sing N N 450 
SRW C11 H13  sing N N 451 
SRW C11 H14  sing N N 452 
SRW C12 H15  sing N N 453 
SRW C12 H16  sing N N 454 
SRW C17 H17  sing N N 455 
SRW C19 H18  sing N N 456 
SRW C20 H19  sing N N 457 
SRW C21 H20  sing N N 458 
SRW C21 H21  sing N N 459 
SRW C21 H22  sing N N 460 
SRW C22 H23  sing N N 461 
SRW C22 H24  sing N N 462 
SRW C23 H25  sing N N 463 
SRW C23 H26  sing N N 464 
SRW O2  H27  sing N N 465 
SRW C25 H28  sing N N 466 
SRW C25 H29  sing N N 467 
SRW C26 H30  sing N N 468 
SRW C26 H31  sing N N 469 
THR N   CA   sing N N 470 
THR N   H    sing N N 471 
THR N   H2   sing N N 472 
THR CA  C    sing N N 473 
THR CA  CB   sing N N 474 
THR CA  HA   sing N N 475 
THR C   O    doub N N 476 
THR C   OXT  sing N N 477 
THR CB  OG1  sing N N 478 
THR CB  CG2  sing N N 479 
THR CB  HB   sing N N 480 
THR OG1 HG1  sing N N 481 
THR CG2 HG21 sing N N 482 
THR CG2 HG22 sing N N 483 
THR CG2 HG23 sing N N 484 
THR OXT HXT  sing N N 485 
TPO N   CA   sing N N 486 
TPO N   H    sing N N 487 
TPO N   H2   sing N N 488 
TPO CA  CB   sing N N 489 
TPO CA  C    sing N N 490 
TPO CA  HA   sing N N 491 
TPO CB  CG2  sing N N 492 
TPO CB  OG1  sing N N 493 
TPO CB  HB   sing N N 494 
TPO CG2 HG21 sing N N 495 
TPO CG2 HG22 sing N N 496 
TPO CG2 HG23 sing N N 497 
TPO OG1 P    sing N N 498 
TPO P   O1P  doub N N 499 
TPO P   O2P  sing N N 500 
TPO P   O3P  sing N N 501 
TPO O2P HOP2 sing N N 502 
TPO O3P HOP3 sing N N 503 
TPO C   O    doub N N 504 
TPO C   OXT  sing N N 505 
TPO OXT HXT  sing N N 506 
TRP N   CA   sing N N 507 
TRP N   H    sing N N 508 
TRP N   H2   sing N N 509 
TRP CA  C    sing N N 510 
TRP CA  CB   sing N N 511 
TRP CA  HA   sing N N 512 
TRP C   O    doub N N 513 
TRP C   OXT  sing N N 514 
TRP CB  CG   sing N N 515 
TRP CB  HB2  sing N N 516 
TRP CB  HB3  sing N N 517 
TRP CG  CD1  doub Y N 518 
TRP CG  CD2  sing Y N 519 
TRP CD1 NE1  sing Y N 520 
TRP CD1 HD1  sing N N 521 
TRP CD2 CE2  doub Y N 522 
TRP CD2 CE3  sing Y N 523 
TRP NE1 CE2  sing Y N 524 
TRP NE1 HE1  sing N N 525 
TRP CE2 CZ2  sing Y N 526 
TRP CE3 CZ3  doub Y N 527 
TRP CE3 HE3  sing N N 528 
TRP CZ2 CH2  doub Y N 529 
TRP CZ2 HZ2  sing N N 530 
TRP CZ3 CH2  sing Y N 531 
TRP CZ3 HZ3  sing N N 532 
TRP CH2 HH2  sing N N 533 
TRP OXT HXT  sing N N 534 
TYR N   CA   sing N N 535 
TYR N   H    sing N N 536 
TYR N   H2   sing N N 537 
TYR CA  C    sing N N 538 
TYR CA  CB   sing N N 539 
TYR CA  HA   sing N N 540 
TYR C   O    doub N N 541 
TYR C   OXT  sing N N 542 
TYR CB  CG   sing N N 543 
TYR CB  HB2  sing N N 544 
TYR CB  HB3  sing N N 545 
TYR CG  CD1  doub Y N 546 
TYR CG  CD2  sing Y N 547 
TYR CD1 CE1  sing Y N 548 
TYR CD1 HD1  sing N N 549 
TYR CD2 CE2  doub Y N 550 
TYR CD2 HD2  sing N N 551 
TYR CE1 CZ   doub Y N 552 
TYR CE1 HE1  sing N N 553 
TYR CE2 CZ   sing Y N 554 
TYR CE2 HE2  sing N N 555 
TYR CZ  OH   sing N N 556 
TYR OH  HH   sing N N 557 
TYR OXT HXT  sing N N 558 
VAL N   CA   sing N N 559 
VAL N   H    sing N N 560 
VAL N   H2   sing N N 561 
VAL CA  C    sing N N 562 
VAL CA  CB   sing N N 563 
VAL CA  HA   sing N N 564 
VAL C   O    doub N N 565 
VAL C   OXT  sing N N 566 
VAL CB  CG1  sing N N 567 
VAL CB  CG2  sing N N 568 
VAL CB  HB   sing N N 569 
VAL CG1 HG11 sing N N 570 
VAL CG1 HG12 sing N N 571 
VAL CG1 HG13 sing N N 572 
VAL CG2 HG21 sing N N 573 
VAL CG2 HG22 sing N N 574 
VAL CG2 HG23 sing N N 575 
VAL OXT HXT  sing N N 576 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-18 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZYT 
_em_admin.last_update        2025-05-28 
_em_admin.map_release_date   2025-04-09 
_em_admin.title              'Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin1 and SBI-553 (complex 3)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK293 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          2021188 
_em_entity_assembly_recombinant.organism             'Mammalian expression vector Flag-MCS-pcDNA3.1' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           1.0 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           T2221005 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8ZYT 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
F 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR A 1 26  ? 142.663 123.876 118.574 1.00 42.02  ? 5   THR B N   1 
ATOM   2    C CA  . THR A 1 26  ? 143.811 123.877 117.676 1.00 44.38  ? 5   THR B CA  1 
ATOM   3    C C   . THR A 1 26  ? 145.113 123.739 118.453 1.00 47.42  ? 5   THR B C   1 
ATOM   4    O O   . THR A 1 26  ? 145.812 122.736 118.330 1.00 47.03  ? 5   THR B O   1 
ATOM   5    C CB  . THR A 1 26  ? 143.862 125.159 116.828 1.00 46.47  ? 5   THR B CB  1 
ATOM   6    O OG1 . THR A 1 26  ? 143.732 126.302 117.681 1.00 46.19  ? 5   THR B OG1 1 
ATOM   7    C CG2 . THR A 1 26  ? 142.739 125.166 115.803 1.00 46.38  ? 5   THR B CG2 1 
ATOM   8    N N   . ARG A 1 27  ? 145.434 124.751 119.253 1.00 38.02  ? 6   ARG B N   1 
ATOM   9    C CA  . ARG A 1 27  ? 146.655 124.734 120.045 1.00 34.71  ? 6   ARG B CA  1 
ATOM   10   C C   . ARG A 1 27  ? 146.426 124.011 121.366 1.00 35.27  ? 6   ARG B C   1 
ATOM   11   O O   . ARG A 1 27  ? 145.343 124.084 121.952 1.00 33.56  ? 6   ARG B O   1 
ATOM   12   C CB  . ARG A 1 27  ? 147.145 126.159 120.305 1.00 35.94  ? 6   ARG B CB  1 
ATOM   13   C CG  . ARG A 1 27  ? 147.973 126.759 119.173 1.00 29.17  ? 6   ARG B CG  1 
ATOM   14   C CD  . ARG A 1 27  ? 149.419 126.291 119.217 1.00 37.69  ? 6   ARG B CD  1 
ATOM   15   N NE  . ARG A 1 27  ? 149.998 126.172 117.884 1.00 36.15  ? 6   ARG B NE  1 
ATOM   16   C CZ  . ARG A 1 27  ? 151.297 126.072 117.635 1.00 35.65  ? 6   ARG B CZ  1 
ATOM   17   N NH1 . ARG A 1 27  ? 152.191 126.071 118.609 1.00 37.23  ? 6   ARG B NH1 1 
ATOM   18   N NH2 . ARG A 1 27  ? 151.710 125.970 116.375 1.00 29.97  ? 6   ARG B NH2 1 
ATOM   19   N N   . VAL A 1 28  ? 147.456 123.303 121.827 1.00 35.38  ? 7   VAL B N   1 
ATOM   20   C CA  . VAL A 1 28  ? 147.418 122.580 123.089 1.00 20.38  ? 7   VAL B CA  1 
ATOM   21   C C   . VAL A 1 28  ? 148.587 123.045 123.949 1.00 27.20  ? 7   VAL B C   1 
ATOM   22   O O   . VAL A 1 28  ? 149.499 123.728 123.484 1.00 39.56  ? 7   VAL B O   1 
ATOM   23   C CB  . VAL A 1 28  ? 147.458 121.051 122.896 1.00 17.42  ? 7   VAL B CB  1 
ATOM   24   C CG1 . VAL A 1 28  ? 146.460 120.621 121.843 1.00 28.86  ? 7   VAL B CG1 1 
ATOM   25   C CG2 . VAL A 1 28  ? 148.855 120.598 122.526 1.00 24.73  ? 7   VAL B CG2 1 
ATOM   26   N N   . PHE A 1 29  ? 148.545 122.666 125.222 1.00 20.49  ? 8   PHE B N   1 
ATOM   27   C CA  . PHE A 1 29  ? 149.579 123.008 126.188 1.00 13.13  ? 8   PHE B CA  1 
ATOM   28   C C   . PHE A 1 29  ? 150.310 121.745 126.612 1.00 11.99  ? 8   PHE B C   1 
ATOM   29   O O   . PHE A 1 29  ? 149.679 120.775 127.038 1.00 22.06  ? 8   PHE B O   1 
ATOM   30   C CB  . PHE A 1 29  ? 148.974 123.700 127.410 1.00 16.21  ? 8   PHE B CB  1 
ATOM   31   C CG  . PHE A 1 29  ? 148.110 124.875 127.070 1.00 20.31  ? 8   PHE B CG  1 
ATOM   32   C CD1 . PHE A 1 29  ? 148.662 126.134 126.916 1.00 21.86  ? 8   PHE B CD1 1 
ATOM   33   C CD2 . PHE A 1 29  ? 146.748 124.722 126.897 1.00 13.07  ? 8   PHE B CD2 1 
ATOM   34   C CE1 . PHE A 1 29  ? 147.871 127.214 126.601 1.00 19.58  ? 8   PHE B CE1 1 
ATOM   35   C CE2 . PHE A 1 29  ? 145.955 125.800 126.581 1.00 20.42  ? 8   PHE B CE2 1 
ATOM   36   C CZ  . PHE A 1 29  ? 146.517 127.047 126.433 1.00 16.62  ? 8   PHE B CZ  1 
ATOM   37   N N   . LYS A 1 30  ? 151.634 121.759 126.500 1.00 20.07  ? 9   LYS B N   1 
ATOM   38   C CA  . LYS A 1 30  ? 152.451 120.613 126.864 1.00 18.82  ? 9   LYS B CA  1 
ATOM   39   C C   . LYS A 1 30  ? 153.590 121.054 127.773 1.00 27.35  ? 9   LYS B C   1 
ATOM   40   O O   . LYS A 1 30  ? 154.089 122.177 127.675 1.00 35.97  ? 9   LYS B O   1 
ATOM   41   C CB  . LYS A 1 30  ? 152.995 119.898 125.620 1.00 19.75  ? 9   LYS B CB  1 
ATOM   42   C CG  . LYS A 1 30  ? 154.392 120.300 125.195 1.00 24.79  ? 9   LYS B CG  1 
ATOM   43   C CD  . LYS A 1 30  ? 154.506 120.289 123.684 1.00 25.11  ? 9   LYS B CD  1 
ATOM   44   C CE  . LYS A 1 30  ? 155.948 120.364 123.232 1.00 30.29  ? 9   LYS B CE  1 
ATOM   45   N NZ  . LYS A 1 30  ? 156.044 120.463 121.750 1.00 29.87  ? 9   LYS B NZ  1 
ATOM   46   N N   . LYS A 1 31  ? 153.981 120.158 128.674 1.00 24.80  ? 10  LYS B N   1 
ATOM   47   C CA  . LYS A 1 31  ? 155.010 120.455 129.667 1.00 16.59  ? 10  LYS B CA  1 
ATOM   48   C C   . LYS A 1 31  ? 155.676 119.144 130.051 1.00 12.96  ? 10  LYS B C   1 
ATOM   49   O O   . LYS A 1 31  ? 155.058 118.307 130.709 1.00 22.63  ? 10  LYS B O   1 
ATOM   50   C CB  . LYS A 1 31  ? 154.407 121.144 130.886 1.00 17.14  ? 10  LYS B CB  1 
ATOM   51   C CG  . LYS A 1 31  ? 155.414 121.557 131.939 1.00 27.62  ? 10  LYS B CG  1 
ATOM   52   C CD  . LYS A 1 31  ? 154.728 122.301 133.066 1.00 21.72  ? 10  LYS B CD  1 
ATOM   53   C CE  . LYS A 1 31  ? 155.693 122.654 134.175 1.00 16.69  ? 10  LYS B CE  1 
ATOM   54   N NZ  . LYS A 1 31  ? 155.014 123.417 135.253 1.00 20.35  ? 10  LYS B NZ  1 
ATOM   55   N N   . ALA A 1 32  ? 156.924 118.965 129.642 1.00 17.33  ? 11  ALA B N   1 
ATOM   56   C CA  . ALA A 1 32  ? 157.616 117.717 129.905 1.00 15.08  ? 11  ALA B CA  1 
ATOM   57   C C   . ALA A 1 32  ? 158.192 117.702 131.316 1.00 29.68  ? 11  ALA B C   1 
ATOM   58   O O   . ALA A 1 32  ? 158.359 118.738 131.962 1.00 36.88  ? 11  ALA B O   1 
ATOM   59   C CB  . ALA A 1 32  ? 158.728 117.490 128.884 1.00 23.90  ? 11  ALA B CB  1 
ATOM   60   N N   . SER A 1 33  ? 158.490 116.498 131.792 1.00 40.38  ? 12  SER B N   1 
ATOM   61   C CA  . SER A 1 33  ? 159.135 116.335 133.079 1.00 29.62  ? 12  SER B CA  1 
ATOM   62   C C   . SER A 1 33  ? 160.572 116.844 133.008 1.00 34.86  ? 12  SER B C   1 
ATOM   63   O O   . SER A 1 33  ? 161.154 116.929 131.925 1.00 45.69  ? 12  SER B O   1 
ATOM   64   C CB  . SER A 1 33  ? 159.102 114.869 133.498 1.00 29.77  ? 12  SER B CB  1 
ATOM   65   O OG  . SER A 1 33  ? 160.172 114.553 134.366 1.00 39.81  ? 12  SER B OG  1 
ATOM   66   N N   . PRO A 1 34  ? 161.158 117.214 134.151 1.00 35.94  ? 13  PRO B N   1 
ATOM   67   C CA  . PRO A 1 34  ? 162.536 117.732 134.132 1.00 43.55  ? 13  PRO B CA  1 
ATOM   68   C C   . PRO A 1 34  ? 163.543 116.842 133.414 1.00 45.57  ? 13  PRO B C   1 
ATOM   69   O O   . PRO A 1 34  ? 164.430 117.370 132.734 1.00 46.42  ? 13  PRO B O   1 
ATOM   70   C CB  . PRO A 1 34  ? 162.872 117.875 135.623 1.00 39.95  ? 13  PRO B CB  1 
ATOM   71   C CG  . PRO A 1 34  ? 161.555 117.890 136.346 1.00 36.42  ? 13  PRO B CG  1 
ATOM   72   C CD  . PRO A 1 34  ? 160.448 117.599 135.380 1.00 35.38  ? 13  PRO B CD  1 
ATOM   73   N N   . ASN A 1 35  ? 163.442 115.519 133.533 1.00 41.93  ? 14  ASN B N   1 
ATOM   74   C CA  . ASN A 1 35  ? 164.330 114.653 132.768 1.00 39.54  ? 14  ASN B CA  1 
ATOM   75   C C   . ASN A 1 35  ? 163.839 114.421 131.347 1.00 44.81  ? 14  ASN B C   1 
ATOM   76   O O   . ASN A 1 35  ? 164.578 113.849 130.539 1.00 51.16  ? 14  ASN B O   1 
ATOM   77   C CB  . ASN A 1 35  ? 164.516 113.300 133.465 1.00 43.56  ? 14  ASN B CB  1 
ATOM   78   C CG  . ASN A 1 35  ? 163.239 112.772 134.070 1.00 44.36  ? 14  ASN B CG  1 
ATOM   79   O OD1 . ASN A 1 35  ? 162.307 113.525 134.329 1.00 51.68  ? 14  ASN B OD1 1 
ATOM   80   N ND2 . ASN A 1 35  ? 163.193 111.468 134.310 1.00 41.04  ? 14  ASN B ND2 1 
ATOM   81   N N   . GLY A 1 36  ? 162.619 114.849 131.023 1.00 46.50  ? 15  GLY B N   1 
ATOM   82   C CA  . GLY A 1 36  ? 162.082 114.722 129.688 1.00 47.38  ? 15  GLY B CA  1 
ATOM   83   C C   . GLY A 1 36  ? 161.368 113.421 129.397 1.00 44.00  ? 15  GLY B C   1 
ATOM   84   O O   . GLY A 1 36  ? 160.835 113.263 128.292 1.00 45.02  ? 15  GLY B O   1 
ATOM   85   N N   . LYS A 1 37  ? 161.328 112.489 130.350 1.00 34.62  ? 16  LYS B N   1 
ATOM   86   C CA  . LYS A 1 37  ? 160.747 111.170 130.129 1.00 38.08  ? 16  LYS B CA  1 
ATOM   87   C C   . LYS A 1 37  ? 159.270 111.104 130.503 1.00 40.30  ? 16  LYS B C   1 
ATOM   88   O O   . LYS A 1 37  ? 158.750 110.013 130.774 1.00 40.58  ? 16  LYS B O   1 
ATOM   89   C CB  . LYS A 1 37  ? 161.545 110.118 130.898 1.00 39.63  ? 16  LYS B CB  1 
ATOM   90   C CG  . LYS A 1 37  ? 163.007 110.064 130.503 1.00 36.51  ? 16  LYS B CG  1 
ATOM   91   C CD  . LYS A 1 37  ? 163.165 109.624 129.061 1.00 40.47  ? 16  LYS B CD  1 
ATOM   92   C CE  . LYS A 1 37  ? 164.620 109.658 128.630 1.00 45.43  ? 16  LYS B CE  1 
ATOM   93   N NZ  . LYS A 1 37  ? 165.454 108.689 129.388 1.00 48.06  ? 16  LYS B NZ  1 
ATOM   94   N N   . LEU A 1 38  ? 158.581 112.243 130.521 1.00 26.93  ? 17  LEU B N   1 
ATOM   95   C CA  . LEU A 1 38  ? 157.154 112.295 130.814 1.00 21.52  ? 17  LEU B CA  1 
ATOM   96   C C   . LEU A 1 38  ? 156.592 113.648 130.402 1.00 24.51  ? 17  LEU B C   1 
ATOM   97   O O   . LEU A 1 38  ? 157.112 114.687 130.814 1.00 32.24  ? 17  LEU B O   1 
ATOM   98   C CB  . LEU A 1 38  ? 156.898 112.041 132.299 1.00 31.50  ? 17  LEU B CB  1 
ATOM   99   C CG  . LEU A 1 38  ? 155.449 112.065 132.785 1.00 24.12  ? 17  LEU B CG  1 
ATOM   100  C CD1 . LEU A 1 38  ? 154.796 110.717 132.591 1.00 23.62  ? 17  LEU B CD1 1 
ATOM   101  C CD2 . LEU A 1 38  ? 155.403 112.463 134.240 1.00 31.01  ? 17  LEU B CD2 1 
ATOM   102  N N   . THR A 1 39  ? 155.535 113.649 129.595 1.00 22.26  ? 18  THR B N   1 
ATOM   103  C CA  . THR A 1 39  ? 154.923 114.876 129.110 1.00 18.22  ? 18  THR B CA  1 
ATOM   104  C C   . THR A 1 39  ? 153.422 114.811 129.331 1.00 11.92  ? 18  THR B C   1 
ATOM   105  O O   . THR A 1 39  ? 152.817 113.745 129.208 1.00 26.56  ? 18  THR B O   1 
ATOM   106  C CB  . THR A 1 39  ? 155.216 115.103 127.620 1.00 28.06  ? 18  THR B CB  1 
ATOM   107  O OG1 . THR A 1 39  ? 156.586 114.787 127.343 1.00 36.29  ? 18  THR B OG1 1 
ATOM   108  C CG2 . THR A 1 39  ? 154.948 116.546 127.231 1.00 24.99  ? 18  THR B CG2 1 
ATOM   109  N N   . VAL A 1 40  ? 152.828 115.953 129.658 1.00 13.66  ? 19  VAL B N   1 
ATOM   110  C CA  . VAL A 1 40  ? 151.388 116.077 129.834 1.00 8.48   ? 19  VAL B CA  1 
ATOM   111  C C   . VAL A 1 40  ? 150.874 117.084 128.818 1.00 12.46  ? 19  VAL B C   1 
ATOM   112  O O   . VAL A 1 40  ? 151.394 118.200 128.729 1.00 24.09  ? 19  VAL B O   1 
ATOM   113  C CB  . VAL A 1 40  ? 151.023 116.509 131.264 1.00 7.56   ? 19  VAL B CB  1 
ATOM   114  C CG1 . VAL A 1 40  ? 149.596 117.008 131.323 1.00 11.03  ? 19  VAL B CG1 1 
ATOM   115  C CG2 . VAL A 1 40  ? 151.206 115.357 132.215 1.00 21.34  ? 19  VAL B CG2 1 
ATOM   116  N N   . TYR A 1 41  ? 149.864 116.687 128.052 1.00 14.95  ? 20  TYR B N   1 
ATOM   117  C CA  . TYR A 1 41  ? 149.220 117.555 127.079 1.00 8.09   ? 20  TYR B CA  1 
ATOM   118  C C   . TYR A 1 41  ? 147.832 117.915 127.582 1.00 2.44   ? 20  TYR B C   1 
ATOM   119  O O   . TYR A 1 41  ? 147.070 117.035 127.991 1.00 18.67  ? 20  TYR B O   1 
ATOM   120  C CB  . TYR A 1 41  ? 149.128 116.882 125.710 1.00 7.65   ? 20  TYR B CB  1 
ATOM   121  C CG  . TYR A 1 41  ? 150.466 116.646 125.056 1.00 13.40  ? 20  TYR B CG  1 
ATOM   122  C CD1 . TYR A 1 41  ? 151.288 115.608 125.472 1.00 23.32  ? 20  TYR B CD1 1 
ATOM   123  C CD2 . TYR A 1 41  ? 150.909 117.457 124.024 1.00 18.52  ? 20  TYR B CD2 1 
ATOM   124  C CE1 . TYR A 1 41  ? 152.511 115.387 124.881 1.00 19.75  ? 20  TYR B CE1 1 
ATOM   125  C CE2 . TYR A 1 41  ? 152.130 117.242 123.426 1.00 21.07  ? 20  TYR B CE2 1 
ATOM   126  C CZ  . TYR A 1 41  ? 152.928 116.206 123.859 1.00 25.36  ? 20  TYR B CZ  1 
ATOM   127  O OH  . TYR A 1 41  ? 154.151 115.987 123.268 1.00 37.65  ? 20  TYR B OH  1 
ATOM   128  N N   . LEU A 1 42  ? 147.512 119.202 127.558 1.00 12.40  ? 21  LEU B N   1 
ATOM   129  C CA  . LEU A 1 42  ? 146.219 119.697 127.997 1.00 18.84  ? 21  LEU B CA  1 
ATOM   130  C C   . LEU A 1 42  ? 145.617 120.557 126.898 1.00 16.73  ? 21  LEU B C   1 
ATOM   131  O O   . LEU A 1 42  ? 146.335 121.168 126.106 1.00 25.15  ? 21  LEU B O   1 
ATOM   132  C CB  . LEU A 1 42  ? 146.338 120.505 129.294 1.00 13.63  ? 21  LEU B CB  1 
ATOM   133  C CG  . LEU A 1 42  ? 146.201 119.725 130.601 1.00 16.68  ? 21  LEU B CG  1 
ATOM   134  C CD1 . LEU A 1 42  ? 146.809 120.504 131.745 1.00 15.11  ? 21  LEU B CD1 1 
ATOM   135  C CD2 . LEU A 1 42  ? 144.748 119.414 130.881 1.00 14.29  ? 21  LEU B CD2 1 
ATOM   136  N N   . GLY A 1 43  ? 144.291 120.588 126.846 1.00 9.00   ? 22  GLY B N   1 
ATOM   137  C CA  . GLY A 1 43  ? 143.616 121.407 125.862 1.00 11.59  ? 22  GLY B CA  1 
ATOM   138  C C   . GLY A 1 43  ? 143.478 122.847 126.306 1.00 17.17  ? 22  GLY B C   1 
ATOM   139  O O   . GLY A 1 43  ? 143.812 123.771 125.561 1.00 22.67  ? 22  GLY B O   1 
ATOM   140  N N   . LYS A 1 44  ? 142.991 123.044 127.526 1.00 25.63  ? 23  LYS B N   1 
ATOM   141  C CA  . LYS A 1 44  ? 142.793 124.361 128.107 1.00 11.31  ? 23  LYS B CA  1 
ATOM   142  C C   . LYS A 1 44  ? 143.494 124.440 129.453 1.00 8.41   ? 23  LYS B C   1 
ATOM   143  O O   . LYS A 1 44  ? 143.798 123.424 130.082 1.00 19.52  ? 23  LYS B O   1 
ATOM   144  C CB  . LYS A 1 44  ? 141.305 124.678 128.299 1.00 9.93   ? 23  LYS B CB  1 
ATOM   145  C CG  . LYS A 1 44  ? 140.430 124.324 127.127 1.00 16.63  ? 23  LYS B CG  1 
ATOM   146  C CD  . LYS A 1 44  ? 139.249 123.488 127.573 1.00 15.96  ? 23  LYS B CD  1 
ATOM   147  C CE  . LYS A 1 44  ? 138.345 124.267 128.503 1.00 19.36  ? 23  LYS B CE  1 
ATOM   148  N NZ  . LYS A 1 44  ? 137.133 123.486 128.863 1.00 29.68  ? 23  LYS B NZ  1 
ATOM   149  N N   . ARG A 1 45  ? 143.753 125.667 129.887 1.00 5.41   ? 24  ARG B N   1 
ATOM   150  C CA  . ARG A 1 45  ? 144.224 125.927 131.236 1.00 8.97   ? 24  ARG B CA  1 
ATOM   151  C C   . ARG A 1 45  ? 143.164 126.596 132.096 1.00 16.41  ? 24  ARG B C   1 
ATOM   152  O O   . ARG A 1 45  ? 143.402 126.825 133.285 1.00 23.86  ? 24  ARG B O   1 
ATOM   153  C CB  . ARG A 1 45  ? 145.494 126.780 131.193 1.00 8.40   ? 24  ARG B CB  1 
ATOM   154  C CG  . ARG A 1 45  ? 146.663 126.057 130.555 1.00 9.30   ? 24  ARG B CG  1 
ATOM   155  C CD  . ARG A 1 45  ? 147.988 126.614 131.010 1.00 7.20   ? 24  ARG B CD  1 
ATOM   156  N NE  . ARG A 1 45  ? 148.330 126.156 132.348 1.00 10.08  ? 24  ARG B NE  1 
ATOM   157  C CZ  . ARG A 1 45  ? 149.257 126.715 133.110 1.00 26.50  ? 24  ARG B CZ  1 
ATOM   158  N NH1 . ARG A 1 45  ? 149.979 127.736 132.683 1.00 23.23  ? 24  ARG B NH1 1 
ATOM   159  N NH2 . ARG A 1 45  ? 149.464 126.239 134.333 1.00 19.54  ? 24  ARG B NH2 1 
ATOM   160  N N   . ASP A 1 46  ? 142.004 126.910 131.525 1.00 7.74   ? 25  ASP B N   1 
ATOM   161  C CA  . ASP A 1 46  ? 140.874 127.477 132.249 1.00 0.00   ? 25  ASP B CA  1 
ATOM   162  C C   . ASP A 1 46  ? 139.661 126.611 131.957 1.00 10.39  ? 25  ASP B C   1 
ATOM   163  O O   . ASP A 1 46  ? 139.281 126.451 130.794 1.00 20.74  ? 25  ASP B O   1 
ATOM   164  C CB  . ASP A 1 46  ? 140.612 128.923 131.825 1.00 13.42  ? 25  ASP B CB  1 
ATOM   165  C CG  . ASP A 1 46  ? 141.411 129.923 132.628 1.00 26.95  ? 25  ASP B CG  1 
ATOM   166  O OD1 . ASP A 1 46  ? 142.580 130.182 132.274 1.00 29.87  ? 25  ASP B OD1 1 
ATOM   167  O OD2 . ASP A 1 46  ? 140.869 130.464 133.609 1.00 36.33  ? 25  ASP B OD2 1 
ATOM   168  N N   . PHE A 1 47  ? 139.059 126.053 133.001 1.00 14.15  ? 26  PHE B N   1 
ATOM   169  C CA  . PHE A 1 47  ? 137.940 125.128 132.862 1.00 13.03  ? 26  PHE B CA  1 
ATOM   170  C C   . PHE A 1 47  ? 136.703 125.768 133.479 1.00 22.51  ? 26  PHE B C   1 
ATOM   171  O O   . PHE A 1 47  ? 136.644 125.978 134.693 1.00 28.66  ? 26  PHE B O   1 
ATOM   172  C CB  . PHE A 1 47  ? 138.272 123.784 133.504 1.00 6.99   ? 26  PHE B CB  1 
ATOM   173  C CG  . PHE A 1 47  ? 139.412 123.075 132.838 1.00 14.06  ? 26  PHE B CG  1 
ATOM   174  C CD1 . PHE A 1 47  ? 140.715 123.331 133.214 1.00 13.76  ? 26  PHE B CD1 1 
ATOM   175  C CD2 . PHE A 1 47  ? 139.183 122.176 131.816 1.00 15.30  ? 26  PHE B CD2 1 
ATOM   176  C CE1 . PHE A 1 47  ? 141.763 122.697 132.592 1.00 18.79  ? 26  PHE B CE1 1 
ATOM   177  C CE2 . PHE A 1 47  ? 140.230 121.539 131.192 1.00 3.56   ? 26  PHE B CE2 1 
ATOM   178  C CZ  . PHE A 1 47  ? 141.521 121.800 131.582 1.00 2.14   ? 26  PHE B CZ  1 
ATOM   179  N N   . VAL A 1 48  ? 135.716 126.067 132.636 1.00 26.01  ? 27  VAL B N   1 
ATOM   180  C CA  . VAL A 1 48  ? 134.565 126.846 133.066 1.00 18.21  ? 27  VAL B CA  1 
ATOM   181  C C   . VAL A 1 48  ? 133.639 125.989 133.914 1.00 16.00  ? 27  VAL B C   1 
ATOM   182  O O   . VAL A 1 48  ? 133.445 124.796 133.648 1.00 25.96  ? 27  VAL B O   1 
ATOM   183  C CB  . VAL A 1 48  ? 133.829 127.416 131.842 1.00 18.71  ? 27  VAL B CB  1 
ATOM   184  C CG1 . VAL A 1 48  ? 132.803 128.450 132.269 1.00 17.37  ? 27  VAL B CG1 1 
ATOM   185  C CG2 . VAL A 1 48  ? 134.824 128.013 130.868 1.00 22.50  ? 27  VAL B CG2 1 
ATOM   186  N N   . ASP A 1 49  ? 133.064 126.596 134.944 1.00 18.03  ? 28  ASP B N   1 
ATOM   187  C CA  . ASP A 1 49  ? 132.036 125.964 135.757 1.00 21.38  ? 28  ASP B CA  1 
ATOM   188  C C   . ASP A 1 49  ? 130.678 126.494 135.321 1.00 28.05  ? 28  ASP B C   1 
ATOM   189  O O   . ASP A 1 49  ? 130.404 127.691 135.448 1.00 28.77  ? 28  ASP B O   1 
ATOM   190  C CB  . ASP A 1 49  ? 132.264 126.238 137.240 1.00 13.75  ? 28  ASP B CB  1 
ATOM   191  C CG  . ASP A 1 49  ? 131.159 125.679 138.113 1.00 24.87  ? 28  ASP B CG  1 
ATOM   192  O OD1 . ASP A 1 49  ? 130.444 124.760 137.667 1.00 25.79  ? 28  ASP B OD1 1 
ATOM   193  O OD2 . ASP A 1 49  ? 131.005 126.158 139.254 1.00 38.42  ? 28  ASP B OD2 1 
ATOM   194  N N   . HIS A 1 50  ? 129.830 125.601 134.814 1.00 34.27  ? 29  HIS B N   1 
ATOM   195  C CA  . HIS A 1 50  ? 128.464 125.944 134.443 1.00 33.22  ? 29  HIS B CA  1 
ATOM   196  C C   . HIS A 1 50  ? 127.477 125.672 135.566 1.00 36.02  ? 29  HIS B C   1 
ATOM   197  O O   . HIS A 1 50  ? 126.310 125.359 135.297 1.00 40.38  ? 29  HIS B O   1 
ATOM   198  C CB  . HIS A 1 50  ? 128.060 125.189 133.177 1.00 34.14  ? 29  HIS B CB  1 
ATOM   199  C CG  . HIS A 1 50  ? 128.945 125.468 132.004 1.00 36.67  ? 29  HIS B CG  1 
ATOM   200  N ND1 . HIS A 1 50  ? 130.126 124.793 131.786 1.00 34.88  ? 29  HIS B ND1 1 
ATOM   201  C CD2 . HIS A 1 50  ? 128.825 126.354 130.988 1.00 37.15  ? 29  HIS B CD2 1 
ATOM   202  C CE1 . HIS A 1 50  ? 130.693 125.248 130.684 1.00 34.67  ? 29  HIS B CE1 1 
ATOM   203  N NE2 . HIS A 1 50  ? 129.924 126.195 130.180 1.00 41.19  ? 29  HIS B NE2 1 
ATOM   204  N N   . ILE A 1 51  ? 127.930 125.758 136.818 1.00 37.31  ? 30  ILE B N   1 
ATOM   205  C CA  . ILE A 1 51  ? 127.111 125.560 138.011 1.00 39.63  ? 30  ILE B CA  1 
ATOM   206  C C   . ILE A 1 51  ? 126.621 124.119 138.075 1.00 43.98  ? 30  ILE B C   1 
ATOM   207  O O   . ILE A 1 51  ? 126.919 123.394 139.032 1.00 44.55  ? 30  ILE B O   1 
ATOM   208  C CB  . ILE A 1 51  ? 125.933 126.550 138.057 1.00 43.45  ? 30  ILE B CB  1 
ATOM   209  C CG1 . ILE A 1 51  ? 126.448 127.988 138.079 1.00 37.69  ? 30  ILE B CG1 1 
ATOM   210  C CG2 . ILE A 1 51  ? 125.066 126.283 139.272 1.00 44.57  ? 30  ILE B CG2 1 
ATOM   211  C CD1 . ILE A 1 51  ? 125.373 129.019 137.839 1.00 43.10  ? 30  ILE B CD1 1 
ATOM   212  N N   . ASP A 1 52  ? 125.860 123.696 137.063 1.00 51.18  ? 31  ASP B N   1 
ATOM   213  C CA  . ASP A 1 52  ? 125.384 122.318 137.021 1.00 48.25  ? 31  ASP B CA  1 
ATOM   214  C C   . ASP A 1 52  ? 126.539 121.336 136.859 1.00 48.03  ? 31  ASP B C   1 
ATOM   215  O O   . ASP A 1 52  ? 126.551 120.276 137.495 1.00 49.30  ? 31  ASP B O   1 
ATOM   216  C CB  . ASP A 1 52  ? 124.371 122.148 135.889 1.00 45.51  ? 31  ASP B CB  1 
ATOM   217  N N   . LEU A 1 53  ? 127.516 121.668 136.019 1.00 41.91  ? 32  LEU B N   1 
ATOM   218  C CA  . LEU A 1 53  ? 128.638 120.776 135.770 1.00 40.37  ? 32  LEU B CA  1 
ATOM   219  C C   . LEU A 1 53  ? 129.858 121.588 135.361 1.00 37.99  ? 32  LEU B C   1 
ATOM   220  O O   . LEU A 1 53  ? 129.746 122.552 134.600 1.00 42.77  ? 32  LEU B O   1 
ATOM   221  C CB  . LEU A 1 53  ? 128.299 119.746 134.685 1.00 40.93  ? 32  LEU B CB  1 
ATOM   222  C CG  . LEU A 1 53  ? 127.887 120.295 133.315 1.00 42.05  ? 32  LEU B CG  1 
ATOM   223  C CD1 . LEU A 1 53  ? 128.547 119.513 132.193 1.00 37.63  ? 32  LEU B CD1 1 
ATOM   224  C CD2 . LEU A 1 53  ? 126.374 120.286 133.156 1.00 42.90  ? 32  LEU B CD2 1 
ATOM   225  N N   . VAL A 1 54  ? 131.013 121.192 135.871 1.00 28.77  ? 33  VAL B N   1 
ATOM   226  C CA  . VAL A 1 54  ? 132.279 121.771 135.440 1.00 26.87  ? 33  VAL B CA  1 
ATOM   227  C C   . VAL A 1 54  ? 132.713 121.098 134.146 1.00 26.17  ? 33  VAL B C   1 
ATOM   228  O O   . VAL A 1 54  ? 132.320 119.964 133.848 1.00 28.24  ? 33  VAL B O   1 
ATOM   229  C CB  . VAL A 1 54  ? 133.349 121.619 136.542 1.00 21.49  ? 33  VAL B CB  1 
ATOM   230  C CG1 . VAL A 1 54  ? 134.527 122.543 136.288 1.00 15.90  ? 33  VAL B CG1 1 
ATOM   231  C CG2 . VAL A 1 54  ? 132.751 121.893 137.905 1.00 27.01  ? 33  VAL B CG2 1 
ATOM   232  N N   . ASP A 1 55  ? 133.513 121.805 133.355 1.00 24.06  ? 34  ASP B N   1 
ATOM   233  C CA  . ASP A 1 55  ? 134.127 121.189 132.195 1.00 21.94  ? 34  ASP B CA  1 
ATOM   234  C C   . ASP A 1 55  ? 135.101 120.102 132.646 1.00 27.77  ? 34  ASP B C   1 
ATOM   235  O O   . ASP A 1 55  ? 135.734 120.223 133.697 1.00 35.01  ? 34  ASP B O   1 
ATOM   236  C CB  . ASP A 1 55  ? 134.856 122.234 131.356 1.00 23.84  ? 34  ASP B CB  1 
ATOM   237  C CG  . ASP A 1 55  ? 133.904 123.103 130.560 1.00 32.40  ? 34  ASP B CG  1 
ATOM   238  O OD1 . ASP A 1 55  ? 132.681 122.872 130.644 1.00 32.07  ? 34  ASP B OD1 1 
ATOM   239  O OD2 . ASP A 1 55  ? 134.375 124.015 129.850 1.00 34.57  ? 34  ASP B OD2 1 
ATOM   240  N N   . PRO A 1 56  ? 135.228 119.018 131.878 1.00 18.79  ? 35  PRO B N   1 
ATOM   241  C CA  . PRO A 1 56  ? 136.107 117.921 132.297 1.00 18.25  ? 35  PRO B CA  1 
ATOM   242  C C   . PRO A 1 56  ? 137.557 118.223 131.946 1.00 13.99  ? 35  PRO B C   1 
ATOM   243  O O   . PRO A 1 56  ? 137.861 118.674 130.840 1.00 24.72  ? 35  PRO B O   1 
ATOM   244  C CB  . PRO A 1 56  ? 135.579 116.715 131.509 1.00 12.99  ? 35  PRO B CB  1 
ATOM   245  C CG  . PRO A 1 56  ? 134.612 117.264 130.495 1.00 13.70  ? 35  PRO B CG  1 
ATOM   246  C CD  . PRO A 1 56  ? 134.616 118.756 130.569 1.00 19.18  ? 35  PRO B CD  1 
ATOM   247  N N   . VAL A 1 57  ? 138.453 117.969 132.895 1.00 9.20   ? 36  VAL B N   1 
ATOM   248  C CA  . VAL A 1 57  ? 139.875 118.169 132.658 1.00 12.14  ? 36  VAL B CA  1 
ATOM   249  C C   . VAL A 1 57  ? 140.403 116.966 131.894 1.00 16.10  ? 36  VAL B C   1 
ATOM   250  O O   . VAL A 1 57  ? 140.825 115.971 132.492 1.00 24.87  ? 36  VAL B O   1 
ATOM   251  C CB  . VAL A 1 57  ? 140.650 118.376 133.971 1.00 14.50  ? 36  VAL B CB  1 
ATOM   252  C CG1 . VAL A 1 57  ? 142.104 118.697 133.678 1.00 7.50   ? 36  VAL B CG1 1 
ATOM   253  C CG2 . VAL A 1 57  ? 140.014 119.480 134.792 1.00 8.55   ? 36  VAL B CG2 1 
ATOM   254  N N   . ASP A 1 58  ? 140.382 117.052 130.570 1.00 14.92  ? 37  ASP B N   1 
ATOM   255  C CA  . ASP A 1 58  ? 140.819 115.970 129.706 1.00 12.24  ? 37  ASP B CA  1 
ATOM   256  C C   . ASP A 1 58  ? 142.192 116.278 129.126 1.00 10.57  ? 37  ASP B C   1 
ATOM   257  O O   . ASP A 1 58  ? 142.569 117.438 128.950 1.00 23.35  ? 37  ASP B O   1 
ATOM   258  C CB  . ASP A 1 58  ? 139.816 115.740 128.576 1.00 18.44  ? 37  ASP B CB  1 
ATOM   259  N N   . GLY A 1 59  ? 142.937 115.223 128.833 1.00 0.00   ? 38  GLY B N   1 
ATOM   260  C CA  . GLY A 1 59  ? 144.262 115.384 128.272 1.00 0.32   ? 38  GLY B CA  1 
ATOM   261  C C   . GLY A 1 59  ? 144.887 114.031 128.040 1.00 12.05  ? 38  GLY B C   1 
ATOM   262  O O   . GLY A 1 59  ? 144.264 112.988 128.254 1.00 35.52  ? 38  GLY B O   1 
ATOM   263  N N   . VAL A 1 60  ? 146.136 114.061 127.582 1.00 11.91  ? 39  VAL B N   1 
ATOM   264  C CA  . VAL A 1 60  ? 146.907 112.851 127.348 1.00 10.72  ? 39  VAL B CA  1 
ATOM   265  C C   . VAL A 1 60  ? 148.251 113.002 128.042 1.00 12.66  ? 39  VAL B C   1 
ATOM   266  O O   . VAL A 1 60  ? 148.710 114.109 128.327 1.00 15.00  ? 39  VAL B O   1 
ATOM   267  C CB  . VAL A 1 60  ? 147.110 112.544 125.844 1.00 16.35  ? 39  VAL B CB  1 
ATOM   268  C CG1 . VAL A 1 60  ? 145.817 112.715 125.077 1.00 25.54  ? 39  VAL B CG1 1 
ATOM   269  C CG2 . VAL A 1 60  ? 148.195 113.418 125.256 1.00 18.10  ? 39  VAL B CG2 1 
ATOM   270  N N   . VAL A 1 61  ? 148.874 111.866 128.329 1.00 22.26  ? 40  VAL B N   1 
ATOM   271  C CA  . VAL A 1 61  ? 150.219 111.824 128.880 1.00 15.65  ? 40  VAL B CA  1 
ATOM   272  C C   . VAL A 1 61  ? 151.069 110.947 127.974 1.00 19.73  ? 40  VAL B C   1 
ATOM   273  O O   . VAL A 1 61  ? 150.683 109.819 127.650 1.00 21.29  ? 40  VAL B O   1 
ATOM   274  C CB  . VAL A 1 61  ? 150.227 111.312 130.333 1.00 11.24  ? 40  VAL B CB  1 
ATOM   275  C CG1 . VAL A 1 61  ? 149.486 110.001 130.447 1.00 23.01  ? 40  VAL B CG1 1 
ATOM   276  C CG2 . VAL A 1 61  ? 151.648 111.166 130.838 1.00 19.05  ? 40  VAL B CG2 1 
ATOM   277  N N   . LEU A 1 62  ? 152.211 111.474 127.548 1.00 28.24  ? 41  LEU B N   1 
ATOM   278  C CA  . LEU A 1 62  ? 153.132 110.754 126.680 1.00 27.88  ? 41  LEU B CA  1 
ATOM   279  C C   . LEU A 1 62  ? 154.259 110.202 127.543 1.00 31.01  ? 41  LEU B C   1 
ATOM   280  O O   . LEU A 1 62  ? 155.034 110.964 128.128 1.00 26.86  ? 41  LEU B O   1 
ATOM   281  C CB  . LEU A 1 62  ? 153.667 111.663 125.578 1.00 24.22  ? 41  LEU B CB  1 
ATOM   282  C CG  . LEU A 1 62  ? 154.470 110.969 124.482 1.00 26.40  ? 41  LEU B CG  1 
ATOM   283  C CD1 . LEU A 1 62  ? 153.554 110.157 123.596 1.00 24.74  ? 41  LEU B CD1 1 
ATOM   284  C CD2 . LEU A 1 62  ? 155.240 111.989 123.670 1.00 33.61  ? 41  LEU B CD2 1 
ATOM   285  N N   . VAL A 1 63  ? 154.346 108.879 127.616 1.00 33.64  ? 42  VAL B N   1 
ATOM   286  C CA  . VAL A 1 63  ? 155.271 108.202 128.507 1.00 30.91  ? 42  VAL B CA  1 
ATOM   287  C C   . VAL A 1 63  ? 156.314 107.462 127.676 1.00 40.03  ? 42  VAL B C   1 
ATOM   288  O O   . VAL A 1 63  ? 156.220 107.369 126.453 1.00 39.51  ? 42  VAL B O   1 
ATOM   289  C CB  . VAL A 1 63  ? 154.542 107.242 129.466 1.00 30.41  ? 42  VAL B CB  1 
ATOM   290  C CG1 . VAL A 1 63  ? 153.544 108.002 130.313 1.00 28.50  ? 42  VAL B CG1 1 
ATOM   291  C CG2 . VAL A 1 63  ? 153.842 106.148 128.681 1.00 32.47  ? 42  VAL B CG2 1 
ATOM   292  N N   . ASP A 1 64  ? 157.321 106.925 128.366 1.00 44.47  ? 43  ASP B N   1 
ATOM   293  C CA  . ASP A 1 64  ? 158.409 106.169 127.747 1.00 46.43  ? 43  ASP B CA  1 
ATOM   294  C C   . ASP A 1 64  ? 158.458 104.793 128.395 1.00 47.07  ? 43  ASP B C   1 
ATOM   295  O O   . ASP A 1 64  ? 159.166 104.594 129.396 1.00 49.38  ? 43  ASP B O   1 
ATOM   296  C CB  . ASP A 1 64  ? 159.740 106.902 127.902 1.00 50.30  ? 43  ASP B CB  1 
ATOM   297  C CG  . ASP A 1 64  ? 160.843 106.298 127.058 1.00 50.25  ? 43  ASP B CG  1 
ATOM   298  O OD1 . ASP A 1 64  ? 161.410 105.266 127.472 1.00 48.89  ? 43  ASP B OD1 1 
ATOM   299  O OD2 . ASP A 1 64  ? 161.146 106.857 125.985 1.00 48.10  ? 43  ASP B OD2 1 
ATOM   300  N N   . PRO A 1 65  ? 157.725 103.812 127.862 1.00 48.50  ? 44  PRO B N   1 
ATOM   301  C CA  . PRO A 1 65  ? 157.680 102.490 128.508 1.00 49.35  ? 44  PRO B CA  1 
ATOM   302  C C   . PRO A 1 65  ? 159.031 101.808 128.605 1.00 52.90  ? 44  PRO B C   1 
ATOM   303  O O   . PRO A 1 65  ? 159.216 100.962 129.489 1.00 51.36  ? 44  PRO B O   1 
ATOM   304  C CB  . PRO A 1 65  ? 156.715 101.696 127.616 1.00 44.64  ? 44  PRO B CB  1 
ATOM   305  C CG  . PRO A 1 65  ? 155.898 102.734 126.923 1.00 41.52  ? 44  PRO B CG  1 
ATOM   306  C CD  . PRO A 1 65  ? 156.824 103.889 126.702 1.00 46.88  ? 44  PRO B CD  1 
ATOM   307  N N   . GLU A 1 66  ? 159.979 102.137 127.727 1.00 57.29  ? 45  GLU B N   1 
ATOM   308  C CA  . GLU A 1 66  ? 161.321 101.583 127.844 1.00 58.75  ? 45  GLU B CA  1 
ATOM   309  C C   . GLU A 1 66  ? 162.087 102.155 129.028 1.00 55.75  ? 45  GLU B C   1 
ATOM   310  O O   . GLU A 1 66  ? 163.148 101.623 129.372 1.00 51.50  ? 45  GLU B O   1 
ATOM   311  C CB  . GLU A 1 66  ? 162.107 101.829 126.555 1.00 55.36  ? 45  GLU B CB  1 
ATOM   312  N N   . TYR A 1 67  ? 161.579 103.216 129.654 1.00 50.99  ? 46  TYR B N   1 
ATOM   313  C CA  . TYR A 1 67  ? 162.232 103.831 130.802 1.00 50.33  ? 46  TYR B CA  1 
ATOM   314  C C   . TYR A 1 67  ? 161.551 103.508 132.121 1.00 47.94  ? 46  TYR B C   1 
ATOM   315  O O   . TYR A 1 67  ? 162.211 103.527 133.164 1.00 50.67  ? 46  TYR B O   1 
ATOM   316  C CB  . TYR A 1 67  ? 162.305 105.355 130.611 1.00 52.23  ? 46  TYR B CB  1 
ATOM   317  C CG  . TYR A 1 67  ? 162.286 106.178 131.886 1.00 56.65  ? 46  TYR B CG  1 
ATOM   318  C CD1 . TYR A 1 67  ? 161.087 106.518 132.510 1.00 56.09  ? 46  TYR B CD1 1 
ATOM   319  C CD2 . TYR A 1 67  ? 163.468 106.603 132.474 1.00 48.15  ? 46  TYR B CD2 1 
ATOM   320  C CE1 . TYR A 1 67  ? 161.071 107.261 133.672 1.00 52.53  ? 46  TYR B CE1 1 
ATOM   321  C CE2 . TYR A 1 67  ? 163.460 107.347 133.636 1.00 49.08  ? 46  TYR B CE2 1 
ATOM   322  C CZ  . TYR A 1 67  ? 162.259 107.672 134.230 1.00 53.12  ? 46  TYR B CZ  1 
ATOM   323  O OH  . TYR A 1 67  ? 162.246 108.413 135.389 1.00 53.23  ? 46  TYR B OH  1 
ATOM   324  N N   . LEU A 1 68  ? 160.249 103.215 132.104 1.00 54.18  ? 47  LEU B N   1 
ATOM   325  C CA  . LEU A 1 68  ? 159.537 102.954 133.350 1.00 58.99  ? 47  LEU B CA  1 
ATOM   326  C C   . LEU A 1 68  ? 160.093 101.725 134.057 1.00 58.24  ? 47  LEU B C   1 
ATOM   327  O O   . LEU A 1 68  ? 160.305 101.747 135.276 1.00 54.16  ? 47  LEU B O   1 
ATOM   328  C CB  . LEU A 1 68  ? 158.042 102.789 133.079 1.00 57.47  ? 47  LEU B CB  1 
ATOM   329  C CG  . LEU A 1 68  ? 157.317 104.001 132.490 1.00 53.56  ? 47  LEU B CG  1 
ATOM   330  C CD1 . LEU A 1 68  ? 156.054 103.570 131.767 1.00 47.14  ? 47  LEU B CD1 1 
ATOM   331  C CD2 . LEU A 1 68  ? 156.999 105.014 133.573 1.00 49.85  ? 47  LEU B CD2 1 
ATOM   332  N N   . LYS A 1 69  ? 160.345 100.649 133.308 1.00 57.38  ? 48  LYS B N   1 
ATOM   333  C CA  . LYS A 1 69  ? 160.898 99.406  133.847 1.00 55.47  ? 48  LYS B CA  1 
ATOM   334  C C   . LYS A 1 69  ? 160.006 98.859  134.966 1.00 57.55  ? 48  LYS B C   1 
ATOM   335  O O   . LYS A 1 69  ? 160.378 98.813  136.141 1.00 61.36  ? 48  LYS B O   1 
ATOM   336  C CB  . LYS A 1 69  ? 162.338 99.610  134.332 1.00 56.37  ? 48  LYS B CB  1 
ATOM   337  C CG  . LYS A 1 69  ? 163.326 99.939  133.227 1.00 56.54  ? 48  LYS B CG  1 
ATOM   338  C CD  . LYS A 1 69  ? 164.304 101.015 133.665 1.00 57.22  ? 48  LYS B CD  1 
ATOM   339  C CE  . LYS A 1 69  ? 165.301 101.334 132.566 1.00 58.43  ? 48  LYS B CE  1 
ATOM   340  N NZ  . LYS A 1 69  ? 166.700 101.356 133.076 1.00 58.33  ? 48  LYS B NZ  1 
ATOM   341  N N   . GLU A 1 70  ? 158.799 98.463  134.558 1.00 53.12  ? 49  GLU B N   1 
ATOM   342  C CA  . GLU A 1 70  ? 157.771 97.951  135.464 1.00 56.08  ? 49  GLU B CA  1 
ATOM   343  C C   . GLU A 1 70  ? 157.391 99.006  136.504 1.00 54.37  ? 49  GLU B C   1 
ATOM   344  O O   . GLU A 1 70  ? 157.533 98.816  137.713 1.00 50.24  ? 49  GLU B O   1 
ATOM   345  C CB  . GLU A 1 70  ? 158.222 96.647  136.133 1.00 51.26  ? 49  GLU B CB  1 
ATOM   346  N N   . ARG A 1 71  ? 156.907 100.138 136.000 1.00 48.89  ? 50  ARG B N   1 
ATOM   347  C CA  . ARG A 1 71  ? 156.463 101.245 136.831 1.00 46.66  ? 50  ARG B CA  1 
ATOM   348  C C   . ARG A 1 71  ? 155.265 101.906 136.173 1.00 43.85  ? 50  ARG B C   1 
ATOM   349  O O   . ARG A 1 71  ? 155.212 102.030 134.948 1.00 46.91  ? 50  ARG B O   1 
ATOM   350  C CB  . ARG A 1 71  ? 157.578 102.272 137.041 1.00 48.10  ? 50  ARG B CB  1 
ATOM   351  C CG  . ARG A 1 71  ? 158.326 102.121 138.347 1.00 45.36  ? 50  ARG B CG  1 
ATOM   352  C CD  . ARG A 1 71  ? 158.663 103.478 138.933 1.00 44.84  ? 50  ARG B CD  1 
ATOM   353  N NE  . ARG A 1 71  ? 159.090 104.423 137.909 1.00 45.79  ? 50  ARG B NE  1 
ATOM   354  C CZ  . ARG A 1 71  ? 160.281 104.413 137.327 1.00 50.08  ? 50  ARG B CZ  1 
ATOM   355  N NH1 . ARG A 1 71  ? 161.198 103.514 137.644 1.00 52.78  ? 50  ARG B NH1 1 
ATOM   356  N NH2 . ARG A 1 71  ? 160.560 105.327 136.404 1.00 51.05  ? 50  ARG B NH2 1 
ATOM   357  N N   . ARG A 1 72  ? 154.313 102.334 136.991 1.00 35.34  ? 51  ARG B N   1 
ATOM   358  C CA  . ARG A 1 72  ? 153.076 102.924 136.510 1.00 37.80  ? 51  ARG B CA  1 
ATOM   359  C C   . ARG A 1 72  ? 153.174 104.444 136.505 1.00 35.86  ? 51  ARG B C   1 
ATOM   360  O O   . ARG A 1 72  ? 154.100 105.036 137.061 1.00 40.87  ? 51  ARG B O   1 
ATOM   361  C CB  . ARG A 1 72  ? 151.898 102.460 137.369 1.00 36.40  ? 51  ARG B CB  1 
ATOM   362  C CG  . ARG A 1 72  ? 151.798 100.953 137.491 1.00 37.27  ? 51  ARG B CG  1 
ATOM   363  C CD  . ARG A 1 72  ? 151.069 100.540 138.749 1.00 37.95  ? 51  ARG B CD  1 
ATOM   364  N NE  . ARG A 1 72  ? 151.990 100.095 139.787 1.00 39.34  ? 51  ARG B NE  1 
ATOM   365  C CZ  . ARG A 1 72  ? 152.607 98.922  139.787 1.00 46.61  ? 51  ARG B CZ  1 
ATOM   366  N NH1 . ARG A 1 72  ? 152.418 98.040  138.820 1.00 42.14  ? 51  ARG B NH1 1 
ATOM   367  N NH2 . ARG A 1 72  ? 153.436 98.626  140.785 1.00 47.17  ? 51  ARG B NH2 1 
ATOM   368  N N   . VAL A 1 73  ? 152.203 105.074 135.850 1.00 33.57  ? 52  VAL B N   1 
ATOM   369  C CA  . VAL A 1 73  ? 152.108 106.526 135.770 1.00 32.58  ? 52  VAL B CA  1 
ATOM   370  C C   . VAL A 1 73  ? 150.732 106.937 136.272 1.00 29.95  ? 52  VAL B C   1 
ATOM   371  O O   . VAL A 1 73  ? 149.713 106.493 135.731 1.00 40.14  ? 52  VAL B O   1 
ATOM   372  C CB  . VAL A 1 73  ? 152.334 107.043 134.340 1.00 25.59  ? 52  VAL B CB  1 
ATOM   373  C CG1 . VAL A 1 73  ? 152.273 108.554 134.312 1.00 27.01  ? 52  VAL B CG1 1 
ATOM   374  C CG2 . VAL A 1 73  ? 153.660 106.556 133.805 1.00 29.84  ? 52  VAL B CG2 1 
ATOM   375  N N   . TYR A 1 74  ? 150.700 107.785 137.293 1.00 25.06  ? 53  TYR B N   1 
ATOM   376  C CA  . TYR A 1 74  ? 149.460 108.269 137.880 1.00 22.18  ? 53  TYR B CA  1 
ATOM   377  C C   . TYR A 1 74  ? 149.314 109.756 137.605 1.00 28.07  ? 53  TYR B C   1 
ATOM   378  O O   . TYR A 1 74  ? 150.302 110.495 137.609 1.00 44.59  ? 53  TYR B O   1 
ATOM   379  C CB  . TYR A 1 74  ? 149.428 108.025 139.391 1.00 30.81  ? 53  TYR B CB  1 
ATOM   380  C CG  . TYR A 1 74  ? 149.576 106.579 139.792 1.00 34.23  ? 53  TYR B CG  1 
ATOM   381  C CD1 . TYR A 1 74  ? 148.471 105.752 139.891 1.00 35.27  ? 53  TYR B CD1 1 
ATOM   382  C CD2 . TYR A 1 74  ? 150.820 106.043 140.080 1.00 32.41  ? 53  TYR B CD2 1 
ATOM   383  C CE1 . TYR A 1 74  ? 148.599 104.434 140.256 1.00 35.52  ? 53  TYR B CE1 1 
ATOM   384  C CE2 . TYR A 1 74  ? 150.957 104.725 140.449 1.00 32.66  ? 53  TYR B CE2 1 
ATOM   385  C CZ  . TYR A 1 74  ? 149.843 103.926 140.535 1.00 39.79  ? 53  TYR B CZ  1 
ATOM   386  O OH  . TYR A 1 74  ? 149.968 102.609 140.904 1.00 46.56  ? 53  TYR B OH  1 
ATOM   387  N N   . VAL A 1 75  ? 148.086 110.195 137.361 1.00 15.66  ? 54  VAL B N   1 
ATOM   388  C CA  . VAL A 1 75  ? 147.786 111.606 137.158 1.00 16.02  ? 54  VAL B CA  1 
ATOM   389  C C   . VAL A 1 75  ? 146.832 112.040 138.261 1.00 14.09  ? 54  VAL B C   1 
ATOM   390  O O   . VAL A 1 75  ? 145.779 111.423 138.455 1.00 20.26  ? 54  VAL B O   1 
ATOM   391  C CB  . VAL A 1 75  ? 147.194 111.875 135.766 1.00 15.03  ? 54  VAL B CB  1 
ATOM   392  C CG1 . VAL A 1 75  ? 147.281 113.350 135.434 1.00 9.69   ? 54  VAL B CG1 1 
ATOM   393  C CG2 . VAL A 1 75  ? 147.926 111.062 134.719 1.00 13.68  ? 54  VAL B CG2 1 
ATOM   394  N N   . THR A 1 76  ? 147.200 113.097 138.978 1.00 22.89  ? 55  THR B N   1 
ATOM   395  C CA  . THR A 1 76  ? 146.443 113.582 140.121 1.00 15.39  ? 55  THR B CA  1 
ATOM   396  C C   . THR A 1 76  ? 145.898 114.973 139.836 1.00 8.27   ? 55  THR B C   1 
ATOM   397  O O   . THR A 1 76  ? 146.575 115.804 139.227 1.00 14.97  ? 55  THR B O   1 
ATOM   398  C CB  . THR A 1 76  ? 147.308 113.626 141.389 1.00 17.02  ? 55  THR B CB  1 
ATOM   399  O OG1 . THR A 1 76  ? 148.174 114.764 141.342 1.00 23.69  ? 55  THR B OG1 1 
ATOM   400  C CG2 . THR A 1 76  ? 148.161 112.383 141.499 1.00 11.56  ? 55  THR B CG2 1 
ATOM   401  N N   . LEU A 1 77  ? 144.667 115.215 140.270 1.00 11.34  ? 56  LEU B N   1 
ATOM   402  C CA  . LEU A 1 77  ? 144.068 116.541 140.270 1.00 11.13  ? 56  LEU B CA  1 
ATOM   403  C C   . LEU A 1 77  ? 143.773 116.924 141.711 1.00 19.43  ? 56  LEU B C   1 
ATOM   404  O O   . LEU A 1 77  ? 143.171 116.142 142.451 1.00 31.32  ? 56  LEU B O   1 
ATOM   405  C CB  . LEU A 1 77  ? 142.788 116.576 139.434 1.00 17.87  ? 56  LEU B CB  1 
ATOM   406  C CG  . LEU A 1 77  ? 142.011 117.891 139.382 1.00 11.12  ? 56  LEU B CG  1 
ATOM   407  C CD1 . LEU A 1 77  ? 142.929 119.055 139.091 1.00 10.17  ? 56  LEU B CD1 1 
ATOM   408  C CD2 . LEU A 1 77  ? 140.924 117.809 138.338 1.00 23.23  ? 56  LEU B CD2 1 
ATOM   409  N N   . THR A 1 78  ? 144.200 118.119 142.110 1.00 20.45  ? 57  THR B N   1 
ATOM   410  C CA  . THR A 1 78  ? 144.100 118.533 143.501 1.00 15.45  ? 57  THR B CA  1 
ATOM   411  C C   . THR A 1 78  ? 143.615 119.971 143.593 1.00 14.41  ? 57  THR B C   1 
ATOM   412  O O   . THR A 1 78  ? 144.152 120.855 142.922 1.00 23.81  ? 57  THR B O   1 
ATOM   413  C CB  . THR A 1 78  ? 145.451 118.384 144.205 1.00 19.54  ? 57  THR B CB  1 
ATOM   414  O OG1 . THR A 1 78  ? 145.770 116.993 144.324 1.00 24.94  ? 57  THR B OG1 1 
ATOM   415  C CG2 . THR A 1 78  ? 145.411 119.003 145.587 1.00 23.85  ? 57  THR B CG2 1 
ATOM   416  N N   . CYS A 1 79  ? 142.603 120.196 144.424 1.00 18.88  ? 58  CYS B N   1 
ATOM   417  C CA  . CYS A 1 79  ? 142.180 121.533 144.817 1.00 8.81   ? 58  CYS B CA  1 
ATOM   418  C C   . CYS A 1 79  ? 142.749 121.825 146.199 1.00 17.35  ? 58  CYS B C   1 
ATOM   419  O O   . CYS A 1 79  ? 142.449 121.109 147.160 1.00 30.56  ? 58  CYS B O   1 
ATOM   420  C CB  . CYS A 1 79  ? 140.658 121.646 144.824 1.00 15.26  ? 58  CYS B CB  1 
ATOM   421  S SG  . CYS A 1 79  ? 140.044 123.280 145.247 1.00 29.37  ? 58  CYS B SG  1 
ATOM   422  N N   . ALA A 1 80  ? 143.569 122.867 146.297 1.00 20.02  ? 59  ALA B N   1 
ATOM   423  C CA  . ALA A 1 80  ? 144.302 123.177 147.515 1.00 16.41  ? 59  ALA B CA  1 
ATOM   424  C C   . ALA A 1 80  ? 143.880 124.535 148.051 1.00 29.21  ? 59  ALA B C   1 
ATOM   425  O O   . ALA A 1 80  ? 143.806 125.509 147.298 1.00 32.00  ? 59  ALA B O   1 
ATOM   426  C CB  . ALA A 1 80  ? 145.810 123.158 147.267 1.00 22.41  ? 59  ALA B CB  1 
ATOM   427  N N   . PHE A 1 81  ? 143.618 124.595 149.352 1.00 41.53  ? 60  PHE B N   1 
ATOM   428  C CA  . PHE A 1 81  ? 143.276 125.827 150.051 1.00 35.03  ? 60  PHE B CA  1 
ATOM   429  C C   . PHE A 1 81  ? 144.395 126.153 151.030 1.00 30.72  ? 60  PHE B C   1 
ATOM   430  O O   . PHE A 1 81  ? 144.745 125.322 151.873 1.00 49.44  ? 60  PHE B O   1 
ATOM   431  C CB  . PHE A 1 81  ? 141.944 125.676 150.783 1.00 35.20  ? 60  PHE B CB  1 
ATOM   432  C CG  . PHE A 1 81  ? 141.310 126.978 151.190 1.00 38.95  ? 60  PHE B CG  1 
ATOM   433  C CD1 . PHE A 1 81  ? 141.980 128.179 151.047 1.00 37.92  ? 60  PHE B CD1 1 
ATOM   434  C CD2 . PHE A 1 81  ? 140.031 126.993 151.724 1.00 44.43  ? 60  PHE B CD2 1 
ATOM   435  C CE1 . PHE A 1 81  ? 141.393 129.365 151.429 1.00 43.87  ? 60  PHE B CE1 1 
ATOM   436  C CE2 . PHE A 1 81  ? 139.437 128.177 152.103 1.00 41.67  ? 60  PHE B CE2 1 
ATOM   437  C CZ  . PHE A 1 81  ? 140.120 129.363 151.955 1.00 45.32  ? 60  PHE B CZ  1 
ATOM   438  N N   . ARG A 1 82  ? 144.954 127.354 150.918 1.00 36.10  ? 61  ARG B N   1 
ATOM   439  C CA  . ARG A 1 82  ? 145.956 127.846 151.855 1.00 50.62  ? 61  ARG B CA  1 
ATOM   440  C C   . ARG A 1 82  ? 145.435 129.117 152.506 1.00 53.43  ? 61  ARG B C   1 
ATOM   441  O O   . ARG A 1 82  ? 145.193 130.113 151.818 1.00 49.28  ? 61  ARG B O   1 
ATOM   442  C CB  . ARG A 1 82  ? 147.288 128.118 151.157 1.00 47.07  ? 61  ARG B CB  1 
ATOM   443  C CG  . ARG A 1 82  ? 147.464 127.408 149.836 1.00 49.27  ? 61  ARG B CG  1 
ATOM   444  C CD  . ARG A 1 82  ? 148.670 127.958 149.097 1.00 55.13  ? 61  ARG B CD  1 
ATOM   445  N NE  . ARG A 1 82  ? 149.906 127.703 149.826 1.00 54.49  ? 61  ARG B NE  1 
ATOM   446  C CZ  . ARG A 1 82  ? 150.849 126.859 149.431 1.00 54.17  ? 61  ARG B CZ  1 
ATOM   447  N NH1 . ARG A 1 82  ? 150.737 126.175 148.304 1.00 50.38  ? 61  ARG B NH1 1 
ATOM   448  N NH2 . ARG A 1 82  ? 151.930 126.694 150.188 1.00 54.80  ? 61  ARG B NH2 1 
ATOM   449  N N   . TYR A 1 83  ? 145.262 129.080 153.826 1.00 66.49  ? 62  TYR B N   1 
ATOM   450  C CA  . TYR A 1 83  ? 144.895 130.268 154.582 1.00 65.20  ? 62  TYR B CA  1 
ATOM   451  C C   . TYR A 1 83  ? 145.177 130.030 156.055 1.00 66.05  ? 62  TYR B C   1 
ATOM   452  O O   . TYR A 1 83  ? 145.175 128.889 156.524 1.00 65.09  ? 62  TYR B O   1 
ATOM   453  C CB  . TYR A 1 83  ? 143.423 130.647 154.392 1.00 63.92  ? 62  TYR B CB  1 
ATOM   454  C CG  . TYR A 1 83  ? 143.114 132.038 154.890 1.00 67.28  ? 62  TYR B CG  1 
ATOM   455  C CD1 . TYR A 1 83  ? 143.804 133.137 154.398 1.00 64.67  ? 62  TYR B CD1 1 
ATOM   456  C CD2 . TYR A 1 83  ? 142.153 132.253 155.868 1.00 64.21  ? 62  TYR B CD2 1 
ATOM   457  C CE1 . TYR A 1 83  ? 143.537 134.410 154.852 1.00 65.65  ? 62  TYR B CE1 1 
ATOM   458  C CE2 . TYR A 1 83  ? 141.879 133.525 156.329 1.00 63.79  ? 62  TYR B CE2 1 
ATOM   459  C CZ  . TYR A 1 83  ? 142.574 134.599 155.815 1.00 68.92  ? 62  TYR B CZ  1 
ATOM   460  O OH  . TYR A 1 83  ? 142.312 135.871 156.265 1.00 70.67  ? 62  TYR B OH  1 
ATOM   461  N N   . GLY A 1 84  ? 145.404 131.124 156.777 1.00 78.94  ? 63  GLY B N   1 
ATOM   462  C CA  . GLY A 1 84  ? 145.628 131.074 158.211 1.00 79.73  ? 63  GLY B CA  1 
ATOM   463  C C   . GLY A 1 84  ? 144.361 131.421 158.968 1.00 79.27  ? 63  GLY B C   1 
ATOM   464  O O   . GLY A 1 84  ? 143.746 132.463 158.730 1.00 79.07  ? 63  GLY B O   1 
ATOM   465  N N   . ARG A 1 85  ? 143.978 130.532 159.881 1.00 92.02  ? 64  ARG B N   1 
ATOM   466  C CA  . ARG A 1 85  ? 142.797 130.743 160.710 1.00 94.02  ? 64  ARG B CA  1 
ATOM   467  C C   . ARG A 1 85  ? 143.066 131.888 161.676 1.00 94.24  ? 64  ARG B C   1 
ATOM   468  O O   . ARG A 1 85  ? 143.898 131.760 162.580 1.00 93.69  ? 64  ARG B O   1 
ATOM   469  C CB  . ARG A 1 85  ? 142.448 129.464 161.465 1.00 91.42  ? 64  ARG B CB  1 
ATOM   470  N N   . GLU A 1 86  ? 142.363 133.007 161.486 1.00 94.32  ? 65  GLU B N   1 
ATOM   471  C CA  . GLU A 1 86  ? 142.587 134.229 162.256 1.00 94.13  ? 65  GLU B CA  1 
ATOM   472  C C   . GLU A 1 86  ? 144.054 134.659 162.154 1.00 95.50  ? 65  GLU B C   1 
ATOM   473  O O   . GLU A 1 86  ? 144.816 134.645 163.123 1.00 95.62  ? 65  GLU B O   1 
ATOM   474  C CB  . GLU A 1 86  ? 142.154 134.047 163.716 1.00 94.04  ? 65  GLU B CB  1 
ATOM   475  N N   . ASP A 1 87  ? 144.427 135.023 160.927 1.00 97.86  ? 66  ASP B N   1 
ATOM   476  C CA  . ASP A 1 87  ? 145.814 135.348 160.617 1.00 98.44  ? 66  ASP B CA  1 
ATOM   477  C C   . ASP A 1 87  ? 146.331 136.459 161.521 1.00 97.90  ? 66  ASP B C   1 
ATOM   478  O O   . ASP A 1 87  ? 145.652 137.463 161.756 1.00 98.24  ? 66  ASP B O   1 
ATOM   479  C CB  . ASP A 1 87  ? 145.940 135.762 159.150 1.00 96.47  ? 66  ASP B CB  1 
ATOM   480  N N   . LEU A 1 88  ? 147.544 136.273 162.026 1.00 95.78  ? 67  LEU B N   1 
ATOM   481  C CA  . LEU A 1 88  ? 148.132 137.187 162.995 1.00 96.83  ? 67  LEU B CA  1 
ATOM   482  C C   . LEU A 1 88  ? 149.642 137.191 162.783 1.00 97.15  ? 67  LEU B C   1 
ATOM   483  O O   . LEU A 1 88  ? 150.135 136.764 161.734 1.00 96.60  ? 67  LEU B O   1 
ATOM   484  C CB  . LEU A 1 88  ? 147.726 136.784 164.423 1.00 97.74  ? 67  LEU B CB  1 
ATOM   485  N N   . ASP A 1 89  ? 150.379 137.690 163.781 1.00 100.44 ? 68  ASP B N   1 
ATOM   486  C CA  . ASP A 1 89  ? 151.836 137.719 163.694 1.00 102.03 ? 68  ASP B CA  1 
ATOM   487  C C   . ASP A 1 89  ? 152.419 136.324 163.508 1.00 100.64 ? 68  ASP B C   1 
ATOM   488  O O   . ASP A 1 89  ? 153.495 136.175 162.917 1.00 98.30  ? 68  ASP B O   1 
ATOM   489  C CB  . ASP A 1 89  ? 152.420 138.376 164.945 1.00 99.25  ? 68  ASP B CB  1 
ATOM   490  N N   . VAL A 1 90  ? 151.734 135.297 164.002 1.00 100.53 ? 69  VAL B N   1 
ATOM   491  C CA  . VAL A 1 90  ? 152.128 133.907 163.808 1.00 100.41 ? 69  VAL B CA  1 
ATOM   492  C C   . VAL A 1 90  ? 151.072 133.245 162.935 1.00 100.82 ? 69  VAL B C   1 
ATOM   493  O O   . VAL A 1 90  ? 149.878 133.279 163.259 1.00 99.41  ? 69  VAL B O   1 
ATOM   494  C CB  . VAL A 1 90  ? 152.285 133.167 165.145 1.00 98.95  ? 69  VAL B CB  1 
ATOM   495  N N   . LEU A 1 91  ? 151.508 132.652 161.825 1.00 97.22  ? 70  LEU B N   1 
ATOM   496  C CA  . LEU A 1 91  ? 150.619 131.960 160.891 1.00 94.14  ? 70  LEU B CA  1 
ATOM   497  C C   . LEU A 1 91  ? 150.832 130.461 161.071 1.00 95.04  ? 70  LEU B C   1 
ATOM   498  O O   . LEU A 1 91  ? 151.745 129.869 160.494 1.00 95.93  ? 70  LEU B O   1 
ATOM   499  C CB  . LEU A 1 91  ? 150.886 132.402 159.457 1.00 92.13  ? 70  LEU B CB  1 
ATOM   500  N N   . GLY A 1 92  ? 149.976 129.845 161.882 1.00 91.61  ? 71  GLY B N   1 
ATOM   501  C CA  . GLY A 1 92  ? 150.100 128.433 162.184 1.00 92.34  ? 71  GLY B CA  1 
ATOM   502  C C   . GLY A 1 92  ? 149.345 127.531 161.229 1.00 94.43  ? 71  GLY B C   1 
ATOM   503  O O   . GLY A 1 92  ? 149.899 126.550 160.723 1.00 93.09  ? 71  GLY B O   1 
ATOM   504  N N   . LEU A 1 93  ? 148.077 127.851 160.976 1.00 83.81  ? 72  LEU B N   1 
ATOM   505  C CA  . LEU A 1 93  ? 147.239 127.044 160.098 1.00 81.65  ? 72  LEU B CA  1 
ATOM   506  C C   . LEU A 1 93  ? 147.392 127.407 158.626 1.00 81.22  ? 72  LEU B C   1 
ATOM   507  O O   . LEU A 1 93  ? 146.775 126.753 157.778 1.00 75.44  ? 72  LEU B O   1 
ATOM   508  C CB  . LEU A 1 93  ? 145.771 127.173 160.512 1.00 79.78  ? 72  LEU B CB  1 
ATOM   509  N N   . THR A 1 94  ? 148.193 128.420 158.301 1.00 74.76  ? 73  THR B N   1 
ATOM   510  C CA  . THR A 1 94  ? 148.383 128.832 156.916 1.00 69.12  ? 73  THR B CA  1 
ATOM   511  C C   . THR A 1 94  ? 149.430 127.975 156.222 1.00 67.66  ? 73  THR B C   1 
ATOM   512  O O   . THR A 1 94  ? 150.378 128.506 155.637 1.00 68.81  ? 73  THR B O   1 
ATOM   513  C CB  . THR A 1 94  ? 148.795 130.304 156.841 1.00 69.41  ? 73  THR B CB  1 
ATOM   514  N N   . PHE A 1 95  ? 149.276 126.653 156.280 1.00 63.26  ? 74  PHE B N   1 
ATOM   515  C CA  . PHE A 1 95  ? 150.202 125.748 155.608 1.00 64.17  ? 74  PHE B CA  1 
ATOM   516  C C   . PHE A 1 95  ? 149.642 125.244 154.283 1.00 63.56  ? 74  PHE B C   1 
ATOM   517  O O   . PHE A 1 95  ? 150.233 125.490 153.227 1.00 62.68  ? 74  PHE B O   1 
ATOM   518  C CB  . PHE A 1 95  ? 150.547 124.568 156.528 1.00 59.77  ? 74  PHE B CB  1 
ATOM   519  N N   . ARG A 1 96  ? 148.492 124.572 154.319 1.00 53.92  ? 75  ARG B N   1 
ATOM   520  C CA  . ARG A 1 96  ? 147.871 123.974 153.142 1.00 52.10  ? 75  ARG B CA  1 
ATOM   521  C C   . ARG A 1 96  ? 146.591 123.283 153.599 1.00 50.14  ? 75  ARG B C   1 
ATOM   522  O O   . ARG A 1 96  ? 146.377 123.052 154.792 1.00 51.47  ? 75  ARG B O   1 
ATOM   523  C CB  . ARG A 1 96  ? 148.817 122.982 152.444 1.00 50.55  ? 75  ARG B CB  1 
ATOM   524  C CG  . ARG A 1 96  ? 148.313 122.375 151.141 1.00 48.82  ? 75  ARG B CG  1 
ATOM   525  C CD  . ARG A 1 96  ? 148.588 120.880 151.093 1.00 52.00  ? 75  ARG B CD  1 
ATOM   526  N NE  . ARG A 1 96  ? 148.335 120.241 152.380 1.00 54.49  ? 75  ARG B NE  1 
ATOM   527  C CZ  . ARG A 1 96  ? 148.345 118.931 152.584 1.00 54.03  ? 75  ARG B CZ  1 
ATOM   528  N NH1 . ARG A 1 96  ? 148.595 118.080 151.602 1.00 53.30  ? 75  ARG B NH1 1 
ATOM   529  N NH2 . ARG A 1 96  ? 148.100 118.463 153.804 1.00 52.24  ? 75  ARG B NH2 1 
ATOM   530  N N   . LYS A 1 97  ? 145.732 122.979 152.632 1.00 45.27  ? 76  LYS B N   1 
ATOM   531  C CA  . LYS A 1 97  ? 144.605 122.079 152.821 1.00 40.73  ? 76  LYS B CA  1 
ATOM   532  C C   . LYS A 1 97  ? 144.273 121.491 151.461 1.00 40.74  ? 76  LYS B C   1 
ATOM   533  O O   . LYS A 1 97  ? 144.679 122.022 150.426 1.00 45.23  ? 76  LYS B O   1 
ATOM   534  C CB  . LYS A 1 97  ? 143.394 122.790 153.428 1.00 39.88  ? 76  LYS B CB  1 
ATOM   535  C CG  . LYS A 1 97  ? 142.532 121.896 154.296 1.00 40.00  ? 76  LYS B CG  1 
ATOM   536  C CD  . LYS A 1 97  ? 141.054 122.176 154.084 1.00 41.48  ? 76  LYS B CD  1 
ATOM   537  C CE  . LYS A 1 97  ? 140.189 121.063 154.650 1.00 43.77  ? 76  LYS B CE  1 
ATOM   538  N NZ  . LYS A 1 97  ? 140.548 119.736 154.083 1.00 41.34  ? 76  LYS B NZ  1 
ATOM   539  N N   . ASP A 1 98  ? 143.550 120.376 151.469 1.00 31.74  ? 77  ASP B N   1 
ATOM   540  C CA  . ASP A 1 98  ? 143.208 119.662 150.241 1.00 24.60  ? 77  ASP B CA  1 
ATOM   541  C C   . ASP A 1 98  ? 141.699 119.450 150.211 1.00 26.13  ? 77  ASP B C   1 
ATOM   542  O O   . ASP A 1 98  ? 141.184 118.523 150.842 1.00 38.83  ? 77  ASP B O   1 
ATOM   543  C CB  . ASP A 1 98  ? 143.960 118.338 150.154 1.00 27.69  ? 77  ASP B CB  1 
ATOM   544  C CG  . ASP A 1 98  ? 145.322 118.486 149.506 1.00 38.12  ? 77  ASP B CG  1 
ATOM   545  O OD1 . ASP A 1 98  ? 145.818 119.626 149.414 1.00 38.55  ? 77  ASP B OD1 1 
ATOM   546  O OD2 . ASP A 1 98  ? 145.900 117.461 149.091 1.00 40.44  ? 77  ASP B OD2 1 
ATOM   547  N N   . LEU A 1 99  ? 140.991 120.308 149.477 1.00 15.04  ? 78  LEU B N   1 
ATOM   548  C CA  . LEU A 1 99  ? 139.539 120.206 149.400 1.00 29.48  ? 78  LEU B CA  1 
ATOM   549  C C   . LEU A 1 99  ? 139.073 119.100 148.465 1.00 27.45  ? 78  LEU B C   1 
ATOM   550  O O   . LEU A 1 99  ? 137.924 118.659 148.574 1.00 21.68  ? 78  LEU B O   1 
ATOM   551  C CB  . LEU A 1 99  ? 138.942 121.544 148.957 1.00 29.64  ? 78  LEU B CB  1 
ATOM   552  C CG  . LEU A 1 99  ? 139.681 122.786 149.457 1.00 26.68  ? 78  LEU B CG  1 
ATOM   553  C CD1 . LEU A 1 99  ? 139.258 124.012 148.681 1.00 29.86  ? 78  LEU B CD1 1 
ATOM   554  C CD2 . LEU A 1 99  ? 139.437 122.986 150.934 1.00 28.85  ? 78  LEU B CD2 1 
ATOM   555  N N   . PHE A 1 100 ? 139.932 118.644 147.554 1.00 24.85  ? 79  PHE B N   1 
ATOM   556  C CA  . PHE A 1 100 ? 139.575 117.596 146.607 1.00 21.84  ? 79  PHE B CA  1 
ATOM   557  C C   . PHE A 1 100 ? 140.827 117.025 145.959 1.00 18.45  ? 79  PHE B C   1 
ATOM   558  O O   . PHE A 1 100 ? 141.656 117.779 145.445 1.00 30.07  ? 79  PHE B O   1 
ATOM   559  C CB  . PHE A 1 100 ? 138.625 118.138 145.540 1.00 24.00  ? 79  PHE B CB  1 
ATOM   560  C CG  . PHE A 1 100 ? 138.483 117.247 144.346 1.00 22.44  ? 79  PHE B CG  1 
ATOM   561  C CD1 . PHE A 1 100 ? 137.748 116.080 144.423 1.00 18.85  ? 79  PHE B CD1 1 
ATOM   562  C CD2 . PHE A 1 100 ? 139.083 117.576 143.146 1.00 24.32  ? 79  PHE B CD2 1 
ATOM   563  C CE1 . PHE A 1 100 ? 137.615 115.259 143.328 1.00 22.19  ? 79  PHE B CE1 1 
ATOM   564  C CE2 . PHE A 1 100 ? 138.954 116.757 142.049 1.00 33.71  ? 79  PHE B CE2 1 
ATOM   565  C CZ  . PHE A 1 100 ? 138.219 115.598 142.140 1.00 26.15  ? 79  PHE B CZ  1 
ATOM   566  N N   . VAL A 1 101 ? 140.991 115.704 145.999 1.00 14.58  ? 80  VAL B N   1 
ATOM   567  C CA  . VAL A 1 101 ? 142.112 115.024 145.360 1.00 15.68  ? 80  VAL B CA  1 
ATOM   568  C C   . VAL A 1 101 ? 141.571 113.837 144.576 1.00 24.30  ? 80  VAL B C   1 
ATOM   569  O O   . VAL A 1 101 ? 140.760 113.064 145.095 1.00 29.36  ? 80  VAL B O   1 
ATOM   570  C CB  . VAL A 1 101 ? 143.171 114.560 146.378 1.00 13.57  ? 80  VAL B CB  1 
ATOM   571  C CG1 . VAL A 1 101 ? 144.436 114.131 145.661 1.00 19.21  ? 80  VAL B CG1 1 
ATOM   572  C CG2 . VAL A 1 101 ? 143.485 115.663 147.369 1.00 23.42  ? 80  VAL B CG2 1 
ATOM   573  N N   . ALA A 1 102 ? 142.019 113.694 143.331 1.00 25.51  ? 81  ALA B N   1 
ATOM   574  C CA  . ALA A 1 102 ? 141.616 112.591 142.472 1.00 13.48  ? 81  ALA B CA  1 
ATOM   575  C C   . ALA A 1 102 ? 142.851 111.942 141.872 1.00 19.32  ? 81  ALA B C   1 
ATOM   576  O O   . ALA A 1 102 ? 143.859 112.607 141.627 1.00 29.29  ? 81  ALA B O   1 
ATOM   577  C CB  . ALA A 1 102 ? 140.679 113.055 141.353 1.00 15.35  ? 81  ALA B CB  1 
ATOM   578  N N   . ASN A 1 103 ? 142.768 110.634 141.645 1.00 19.17  ? 82  ASN B N   1 
ATOM   579  C CA  . ASN A 1 103 ? 143.880 109.853 141.125 1.00 17.45  ? 82  ASN B CA  1 
ATOM   580  C C   . ASN A 1 103 ? 143.415 109.030 139.935 1.00 28.83  ? 82  ASN B C   1 
ATOM   581  O O   . ASN A 1 103 ? 142.279 108.552 139.897 1.00 41.78  ? 82  ASN B O   1 
ATOM   582  C CB  . ASN A 1 103 ? 144.463 108.922 142.193 1.00 24.83  ? 82  ASN B CB  1 
ATOM   583  C CG  . ASN A 1 103 ? 145.304 109.657 143.214 1.00 35.43  ? 82  ASN B CG  1 
ATOM   584  O OD1 . ASN A 1 103 ? 146.282 110.312 142.871 1.00 37.01  ? 82  ASN B OD1 1 
ATOM   585  N ND2 . ASN A 1 103 ? 144.927 109.545 144.480 1.00 39.71  ? 82  ASN B ND2 1 
ATOM   586  N N   . VAL A 1 104 ? 144.308 108.870 138.960 1.00 25.82  ? 83  VAL B N   1 
ATOM   587  C CA  . VAL A 1 104 ? 144.038 108.092 137.755 1.00 20.43  ? 83  VAL B CA  1 
ATOM   588  C C   . VAL A 1 104 ? 145.323 107.377 137.363 1.00 27.68  ? 83  VAL B C   1 
ATOM   589  O O   . VAL A 1 104 ? 146.357 108.024 137.170 1.00 35.74  ? 83  VAL B O   1 
ATOM   590  C CB  . VAL A 1 104 ? 143.544 108.973 136.592 1.00 21.43  ? 83  VAL B CB  1 
ATOM   591  C CG1 . VAL A 1 104 ? 143.726 108.262 135.266 1.00 26.54  ? 83  VAL B CG1 1 
ATOM   592  C CG2 . VAL A 1 104 ? 142.090 109.358 136.787 1.00 25.16  ? 83  VAL B CG2 1 
ATOM   593  N N   . GLN A 1 105 ? 145.270 106.052 137.253 1.00 30.18  ? 84  GLN B N   1 
ATOM   594  C CA  . GLN A 1 105 ? 146.392 105.301 136.702 1.00 30.29  ? 84  GLN B CA  1 
ATOM   595  C C   . GLN A 1 105 ? 146.315 105.359 135.184 1.00 36.37  ? 84  GLN B C   1 
ATOM   596  O O   . GLN A 1 105 ? 145.325 104.918 134.591 1.00 42.53  ? 84  GLN B O   1 
ATOM   597  C CB  . GLN A 1 105 ? 146.378 103.856 137.188 1.00 32.74  ? 84  GLN B CB  1 
ATOM   598  C CG  . GLN A 1 105 ? 147.645 103.100 136.853 1.00 33.19  ? 84  GLN B CG  1 
ATOM   599  C CD  . GLN A 1 105 ? 147.453 101.605 136.886 1.00 39.15  ? 84  GLN B CD  1 
ATOM   600  O OE1 . GLN A 1 105 ? 147.571 100.976 137.935 1.00 44.53  ? 84  GLN B OE1 1 
ATOM   601  N NE2 . GLN A 1 105 ? 147.152 101.024 135.733 1.00 38.98  ? 84  GLN B NE2 1 
ATOM   602  N N   . SER A 1 106 ? 147.355 105.897 134.550 1.00 36.65  ? 85  SER B N   1 
ATOM   603  C CA  . SER A 1 106 ? 147.262 106.302 133.156 1.00 33.83  ? 85  SER B CA  1 
ATOM   604  C C   . SER A 1 106 ? 148.019 105.396 132.199 1.00 36.67  ? 85  SER B C   1 
ATOM   605  O O   . SER A 1 106 ? 147.477 105.026 131.155 1.00 48.72  ? 85  SER B O   1 
ATOM   606  C CB  . SER A 1 106 ? 147.753 107.746 132.999 1.00 35.42  ? 85  SER B CB  1 
ATOM   607  O OG  . SER A 1 106 ? 147.216 108.326 131.828 1.00 37.77  ? 85  SER B OG  1 
ATOM   608  N N   . PHE A 1 107 ? 149.271 105.032 132.504 1.00 33.89  ? 86  PHE B N   1 
ATOM   609  C CA  . PHE A 1 107 ? 150.029 104.240 131.536 1.00 37.92  ? 86  PHE B CA  1 
ATOM   610  C C   . PHE A 1 107 ? 149.481 102.826 131.406 1.00 45.15  ? 86  PHE B C   1 
ATOM   611  O O   . PHE A 1 107 ? 149.120 102.425 130.286 1.00 49.95  ? 86  PHE B O   1 
ATOM   612  C CB  . PHE A 1 107 ? 151.520 104.248 131.879 1.00 45.96  ? 86  PHE B CB  1 
ATOM   613  C CG  . PHE A 1 107 ? 152.262 103.077 131.306 1.00 41.31  ? 86  PHE B CG  1 
ATOM   614  C CD1 . PHE A 1 107 ? 152.355 102.906 129.936 1.00 37.69  ? 86  PHE B CD1 1 
ATOM   615  C CD2 . PHE A 1 107 ? 152.842 102.132 132.133 1.00 44.88  ? 86  PHE B CD2 1 
ATOM   616  C CE1 . PHE A 1 107 ? 153.020 101.826 129.402 1.00 45.18  ? 86  PHE B CE1 1 
ATOM   617  C CE2 . PHE A 1 107 ? 153.513 101.050 131.605 1.00 47.70  ? 86  PHE B CE2 1 
ATOM   618  C CZ  . PHE A 1 107 ? 153.602 100.897 130.238 1.00 47.33  ? 86  PHE B CZ  1 
ATOM   619  N N   . PRO A 1 108 ? 149.404 102.019 132.462 1.00 52.70  ? 87  PRO B N   1 
ATOM   620  C CA  . PRO A 1 108 ? 148.865 100.674 132.302 1.00 52.45  ? 87  PRO B CA  1 
ATOM   621  C C   . PRO A 1 108 ? 147.352 100.700 132.371 1.00 52.12  ? 87  PRO B C   1 
ATOM   622  O O   . PRO A 1 108 ? 146.775 100.996 133.428 1.00 55.77  ? 87  PRO B O   1 
ATOM   623  C CB  . PRO A 1 108 ? 149.466 99.903  133.490 1.00 48.53  ? 87  PRO B CB  1 
ATOM   624  C CG  . PRO A 1 108 ? 150.290 100.912 134.267 1.00 48.35  ? 87  PRO B CG  1 
ATOM   625  C CD  . PRO A 1 108 ? 149.783 102.252 133.863 1.00 46.09  ? 87  PRO B CD  1 
ATOM   626  N N   . PRO A 1 109 ? 146.669 100.397 131.274 1.00 59.26  ? 88  PRO B N   1 
ATOM   627  C CA  . PRO A 1 109 ? 145.203 100.381 131.313 1.00 65.12  ? 88  PRO B CA  1 
ATOM   628  C C   . PRO A 1 109 ? 144.676 99.151  132.036 1.00 72.64  ? 88  PRO B C   1 
ATOM   629  O O   . PRO A 1 109 ? 143.869 98.394  131.488 1.00 69.98  ? 88  PRO B O   1 
ATOM   630  C CB  . PRO A 1 109 ? 144.807 100.386 129.829 1.00 67.15  ? 88  PRO B CB  1 
ATOM   631  C CG  . PRO A 1 109 ? 146.096 100.597 129.055 1.00 63.45  ? 88  PRO B CG  1 
ATOM   632  C CD  . PRO A 1 109 ? 147.183 100.088 129.933 1.00 60.00  ? 88  PRO B CD  1 
ATOM   633  N N   . ALA A 1 110 ? 145.151 98.938  133.264 1.00 81.40  ? 89  ALA B N   1 
ATOM   634  C CA  . ALA A 1 110 ? 144.644 97.837  134.077 1.00 78.48  ? 89  ALA B CA  1 
ATOM   635  C C   . ALA A 1 110 ? 143.145 97.935  134.345 1.00 80.96  ? 89  ALA B C   1 
ATOM   636  O O   . ALA A 1 110 ? 142.463 96.902  134.234 1.00 78.57  ? 89  ALA B O   1 
ATOM   637  C CB  . ALA A 1 110 ? 145.437 97.752  135.389 1.00 75.86  ? 89  ALA B CB  1 
ATOM   638  N N   . PRO A 1 111 ? 142.573 99.094  134.694 1.00 92.37  ? 90  PRO B N   1 
ATOM   639  C CA  . PRO A 1 111 ? 141.106 99.170  134.794 1.00 91.19  ? 90  PRO B CA  1 
ATOM   640  C C   . PRO A 1 111 ? 140.400 98.926  133.475 1.00 88.93  ? 90  PRO B C   1 
ATOM   641  O O   . PRO A 1 111 ? 139.199 98.630  133.482 1.00 88.62  ? 90  PRO B O   1 
ATOM   642  C CB  . PRO A 1 111 ? 140.858 100.597 135.304 1.00 91.93  ? 90  PRO B CB  1 
ATOM   643  C CG  . PRO A 1 111 ? 142.136 101.005 135.940 1.00 89.06  ? 90  PRO B CG  1 
ATOM   644  C CD  . PRO A 1 111 ? 143.203 100.356 135.125 1.00 87.89  ? 90  PRO B CD  1 
ATOM   645  N N   . GLU A 1 112 ? 141.107 99.040  132.348 1.00 92.74  ? 91  GLU B N   1 
ATOM   646  C CA  . GLU A 1 112 ? 140.516 98.896  131.018 1.00 94.38  ? 91  GLU B CA  1 
ATOM   647  C C   . GLU A 1 112 ? 139.355 99.869  130.832 1.00 94.56  ? 91  GLU B C   1 
ATOM   648  O O   . GLU A 1 112 ? 138.315 99.526  130.267 1.00 94.44  ? 91  GLU B O   1 
ATOM   649  C CB  . GLU A 1 112 ? 140.071 97.454  130.758 1.00 93.45  ? 91  GLU B CB  1 
ATOM   650  N N   . ASP A 1 113 ? 139.541 101.096 131.318 1.00 96.85  ? 92  ASP B N   1 
ATOM   651  C CA  . ASP A 1 113 ? 138.501 102.114 131.271 1.00 96.85  ? 92  ASP B CA  1 
ATOM   652  C C   . ASP A 1 113 ? 138.116 102.432 129.833 1.00 97.74  ? 92  ASP B C   1 
ATOM   653  O O   . ASP A 1 113 ? 138.913 103.000 129.080 1.00 97.85  ? 92  ASP B O   1 
ATOM   654  C CB  . ASP A 1 113 ? 138.962 103.384 131.990 1.00 96.31  ? 92  ASP B CB  1 
ATOM   655  N N   . LYS A 1 114 ? 136.895 102.062 129.446 1.00 96.16  ? 93  LYS B N   1 
ATOM   656  C CA  . LYS A 1 114 ? 136.366 102.352 128.120 1.00 95.12  ? 93  LYS B CA  1 
ATOM   657  C C   . LYS A 1 114 ? 135.637 103.685 128.067 1.00 94.66  ? 93  LYS B C   1 
ATOM   658  O O   . LYS A 1 114 ? 134.742 103.867 127.229 1.00 95.28  ? 93  LYS B O   1 
ATOM   659  C CB  . LYS A 1 114 ? 135.447 101.219 127.661 1.00 94.29  ? 93  LYS B CB  1 
ATOM   660  N N   . LYS A 1 115 ? 135.989 104.615 128.949 1.00 80.83  ? 94  LYS B N   1 
ATOM   661  C CA  . LYS A 1 115 ? 135.359 105.925 128.953 1.00 80.99  ? 94  LYS B CA  1 
ATOM   662  C C   . LYS A 1 115 ? 135.585 106.609 127.607 1.00 80.60  ? 94  LYS B C   1 
ATOM   663  O O   . LYS A 1 115 ? 136.675 106.499 127.032 1.00 80.92  ? 94  LYS B O   1 
ATOM   664  C CB  . LYS A 1 115 ? 135.930 106.780 130.087 1.00 79.14  ? 94  LYS B CB  1 
ATOM   665  C CG  . LYS A 1 115 ? 135.125 108.019 130.430 1.00 78.40  ? 94  LYS B CG  1 
ATOM   666  C CD  . LYS A 1 115 ? 135.673 108.697 131.676 1.00 79.28  ? 94  LYS B CD  1 
ATOM   667  C CE  . LYS A 1 115 ? 134.650 109.631 132.300 1.00 80.24  ? 94  LYS B CE  1 
ATOM   668  N NZ  . LYS A 1 115 ? 135.144 110.227 133.572 1.00 78.26  ? 94  LYS B NZ  1 
ATOM   669  N N   . PRO A 1 116 ? 134.579 107.296 127.065 1.00 68.23  ? 95  PRO B N   1 
ATOM   670  C CA  . PRO A 1 116 ? 134.737 107.910 125.741 1.00 66.50  ? 95  PRO B CA  1 
ATOM   671  C C   . PRO A 1 116 ? 135.913 108.875 125.701 1.00 64.24  ? 95  PRO B C   1 
ATOM   672  O O   . PRO A 1 116 ? 136.179 109.605 126.656 1.00 64.97  ? 95  PRO B O   1 
ATOM   673  C CB  . PRO A 1 116 ? 133.407 108.639 125.520 1.00 66.72  ? 95  PRO B CB  1 
ATOM   674  C CG  . PRO A 1 116 ? 132.436 107.994 126.434 1.00 67.37  ? 95  PRO B CG  1 
ATOM   675  C CD  . PRO A 1 116 ? 133.190 107.342 127.553 1.00 66.77  ? 95  PRO B CD  1 
ATOM   676  N N   . LEU A 1 117 ? 136.621 108.858 124.578 1.00 53.19  ? 96  LEU B N   1 
ATOM   677  C CA  . LEU A 1 117 ? 137.773 109.723 124.383 1.00 47.60  ? 96  LEU B CA  1 
ATOM   678  C C   . LEU A 1 117 ? 137.336 111.086 123.868 1.00 47.13  ? 96  LEU B C   1 
ATOM   679  O O   . LEU A 1 117 ? 136.474 111.189 122.991 1.00 50.49  ? 96  LEU B O   1 
ATOM   680  C CB  . LEU A 1 117 ? 138.750 109.086 123.397 1.00 54.70  ? 96  LEU B CB  1 
ATOM   681  C CG  . LEU A 1 117 ? 139.735 108.062 123.951 1.00 50.05  ? 96  LEU B CG  1 
ATOM   682  C CD1 . LEU A 1 117 ? 140.051 107.011 122.908 1.00 49.14  ? 96  LEU B CD1 1 
ATOM   683  C CD2 . LEU A 1 117 ? 140.994 108.770 124.373 1.00 46.97  ? 96  LEU B CD2 1 
ATOM   684  N N   . THR A 1 118 ? 137.931 112.136 124.425 1.00 43.40  ? 97  THR B N   1 
ATOM   685  C CA  . THR A 1 118 ? 137.713 113.476 123.904 1.00 43.06  ? 97  THR B CA  1 
ATOM   686  C C   . THR A 1 118 ? 138.315 113.588 122.511 1.00 46.42  ? 97  THR B C   1 
ATOM   687  O O   . THR A 1 118 ? 139.362 113.003 122.227 1.00 41.86  ? 97  THR B O   1 
ATOM   688  C CB  . THR A 1 118 ? 138.337 114.518 124.833 1.00 39.38  ? 97  THR B CB  1 
ATOM   689  O OG1 . THR A 1 118 ? 137.985 114.222 126.189 1.00 44.33  ? 97  THR B OG1 1 
ATOM   690  C CG2 . THR A 1 118 ? 137.841 115.908 124.488 1.00 41.87  ? 97  THR B CG2 1 
ATOM   691  N N   . ARG A 1 119 ? 137.642 114.339 121.634 1.00 47.83  ? 98  ARG B N   1 
ATOM   692  C CA  . ARG A 1 119 ? 138.177 114.571 120.296 1.00 42.81  ? 98  ARG B CA  1 
ATOM   693  C C   . ARG A 1 119 ? 139.595 115.119 120.365 1.00 47.45  ? 98  ARG B C   1 
ATOM   694  O O   . ARG A 1 119 ? 140.456 114.750 119.557 1.00 48.82  ? 98  ARG B O   1 
ATOM   695  C CB  . ARG A 1 119 ? 137.267 115.527 119.525 1.00 43.69  ? 98  ARG B CB  1 
ATOM   696  N N   . LEU A 1 120 ? 139.859 115.988 121.341 1.00 42.07  ? 99  LEU B N   1 
ATOM   697  C CA  . LEU A 1 120 ? 141.222 116.442 121.587 1.00 38.89  ? 99  LEU B CA  1 
ATOM   698  C C   . LEU A 1 120 ? 142.134 115.275 121.942 1.00 39.14  ? 99  LEU B C   1 
ATOM   699  O O   . LEU A 1 120 ? 143.270 115.195 121.460 1.00 42.73  ? 99  LEU B O   1 
ATOM   700  C CB  . LEU A 1 120 ? 141.223 117.485 122.703 1.00 40.37  ? 99  LEU B CB  1 
ATOM   701  C CG  . LEU A 1 120 ? 142.536 117.709 123.451 1.00 41.36  ? 99  LEU B CG  1 
ATOM   702  C CD1 . LEU A 1 120 ? 143.407 118.705 122.708 1.00 39.68  ? 99  LEU B CD1 1 
ATOM   703  C CD2 . LEU A 1 120 ? 142.268 118.168 124.875 1.00 35.09  ? 99  LEU B CD2 1 
ATOM   704  N N   . GLN A 1 121 ? 141.649 114.358 122.783 1.00 36.51  ? 100 GLN B N   1 
ATOM   705  C CA  . GLN A 1 121 ? 142.449 113.196 123.156 1.00 40.40  ? 100 GLN B CA  1 
ATOM   706  C C   . GLN A 1 121 ? 142.750 112.320 121.947 1.00 44.47  ? 100 GLN B C   1 
ATOM   707  O O   . GLN A 1 121 ? 143.880 111.849 121.782 1.00 40.12  ? 100 GLN B O   1 
ATOM   708  C CB  . GLN A 1 121 ? 141.731 112.387 124.236 1.00 41.55  ? 100 GLN B CB  1 
ATOM   709  C CG  . GLN A 1 121 ? 142.222 112.651 125.648 1.00 34.24  ? 100 GLN B CG  1 
ATOM   710  C CD  . GLN A 1 121 ? 141.194 112.293 126.700 1.00 36.76  ? 100 GLN B CD  1 
ATOM   711  O OE1 . GLN A 1 121 ? 140.009 112.157 126.406 1.00 41.39  ? 100 GLN B OE1 1 
ATOM   712  N NE2 . GLN A 1 121 ? 141.645 112.134 127.936 1.00 34.49  ? 100 GLN B NE2 1 
ATOM   713  N N   . GLU A 1 122 ? 141.752 112.092 121.088 1.00 48.23  ? 101 GLU B N   1 
ATOM   714  C CA  . GLU A 1 122 ? 141.971 111.276 119.897 1.00 46.97  ? 101 GLU B CA  1 
ATOM   715  C C   . GLU A 1 122 ? 142.963 111.933 118.946 1.00 41.19  ? 101 GLU B C   1 
ATOM   716  O O   . GLU A 1 122 ? 143.851 111.262 118.404 1.00 41.23  ? 101 GLU B O   1 
ATOM   717  C CB  . GLU A 1 122 ? 140.642 111.009 119.191 1.00 45.56  ? 101 GLU B CB  1 
ATOM   718  C CG  . GLU A 1 122 ? 139.480 110.766 120.138 1.00 47.29  ? 101 GLU B CG  1 
ATOM   719  C CD  . GLU A 1 122 ? 138.130 110.817 119.447 1.00 53.73  ? 101 GLU B CD  1 
ATOM   720  O OE1 . GLU A 1 122 ? 137.906 111.739 118.636 1.00 57.63  ? 101 GLU B OE1 1 
ATOM   721  O OE2 . GLU A 1 122 ? 137.288 109.938 119.725 1.00 50.03  ? 101 GLU B OE2 1 
ATOM   722  N N   . ARG A 1 123 ? 142.836 113.246 118.734 1.00 39.42  ? 102 ARG B N   1 
ATOM   723  C CA  . ARG A 1 123 ? 143.776 113.940 117.859 1.00 47.22  ? 102 ARG B CA  1 
ATOM   724  C C   . ARG A 1 123 ? 145.194 113.886 118.412 1.00 46.66  ? 102 ARG B C   1 
ATOM   725  O O   . ARG A 1 123 ? 146.151 113.637 117.665 1.00 44.89  ? 102 ARG B O   1 
ATOM   726  C CB  . ARG A 1 123 ? 143.335 115.389 117.655 1.00 45.74  ? 102 ARG B CB  1 
ATOM   727  C CG  . ARG A 1 123 ? 141.989 115.543 116.971 1.00 48.47  ? 102 ARG B CG  1 
ATOM   728  C CD  . ARG A 1 123 ? 141.745 116.983 116.554 1.00 48.72  ? 102 ARG B CD  1 
ATOM   729  N NE  . ARG A 1 123 ? 142.948 117.600 116.008 1.00 51.09  ? 102 ARG B NE  1 
ATOM   730  C CZ  . ARG A 1 123 ? 142.952 118.669 115.223 1.00 52.27  ? 102 ARG B CZ  1 
ATOM   731  N NH1 . ARG A 1 123 ? 141.829 119.272 114.871 1.00 55.15  ? 102 ARG B NH1 1 
ATOM   732  N NH2 . ARG A 1 123 ? 144.113 119.143 114.778 1.00 46.78  ? 102 ARG B NH2 1 
ATOM   733  N N   . LEU A 1 124 ? 145.352 114.107 119.720 1.00 39.38  ? 103 LEU B N   1 
ATOM   734  C CA  . LEU A 1 124 ? 146.681 114.068 120.320 1.00 36.55  ? 103 LEU B CA  1 
ATOM   735  C C   . LEU A 1 124 ? 147.272 112.665 120.276 1.00 39.89  ? 103 LEU B C   1 
ATOM   736  O O   . LEU A 1 124 ? 148.478 112.502 120.064 1.00 35.95  ? 103 LEU B O   1 
ATOM   737  C CB  . LEU A 1 124 ? 146.625 114.582 121.756 1.00 36.09  ? 103 LEU B CB  1 
ATOM   738  C CG  . LEU A 1 124 ? 146.652 116.100 121.927 1.00 33.06  ? 103 LEU B CG  1 
ATOM   739  C CD1 . LEU A 1 124 ? 146.251 116.478 123.337 1.00 37.21  ? 103 LEU B CD1 1 
ATOM   740  C CD2 . LEU A 1 124 ? 148.024 116.641 121.597 1.00 33.82  ? 103 LEU B CD2 1 
ATOM   741  N N   . ILE A 1 125 ? 146.443 111.640 120.483 1.00 43.84  ? 104 ILE B N   1 
ATOM   742  C CA  . ILE A 1 125 ? 146.926 110.265 120.404 1.00 40.36  ? 104 ILE B CA  1 
ATOM   743  C C   . ILE A 1 125 ? 147.381 109.941 118.988 1.00 43.38  ? 104 ILE B C   1 
ATOM   744  O O   . ILE A 1 125 ? 148.432 109.322 118.787 1.00 45.39  ? 104 ILE B O   1 
ATOM   745  C CB  . ILE A 1 125 ? 145.838 109.291 120.891 1.00 39.52  ? 104 ILE B CB  1 
ATOM   746  C CG1 . ILE A 1 125 ? 145.810 109.252 122.418 1.00 41.18  ? 104 ILE B CG1 1 
ATOM   747  C CG2 . ILE A 1 125 ? 146.072 107.900 120.332 1.00 44.14  ? 104 ILE B CG2 1 
ATOM   748  C CD1 . ILE A 1 125 ? 145.022 108.099 122.984 1.00 42.72  ? 104 ILE B CD1 1 
ATOM   749  N N   . LYS A 1 126 ? 146.605 110.359 117.985 1.00 47.35  ? 105 LYS B N   1 
ATOM   750  C CA  . LYS A 1 126 ? 147.003 110.121 116.602 1.00 47.50  ? 105 LYS B CA  1 
ATOM   751  C C   . LYS A 1 126 ? 148.310 110.833 116.276 1.00 45.11  ? 105 LYS B C   1 
ATOM   752  O O   . LYS A 1 126 ? 149.183 110.269 115.606 1.00 47.80  ? 105 LYS B O   1 
ATOM   753  C CB  . LYS A 1 126 ? 145.894 110.568 115.652 1.00 44.92  ? 105 LYS B CB  1 
ATOM   754  N N   . LYS A 1 127 ? 148.467 112.073 116.745 1.00 41.07  ? 106 LYS B N   1 
ATOM   755  C CA  . LYS A 1 127 ? 149.700 112.807 116.479 1.00 42.87  ? 106 LYS B CA  1 
ATOM   756  C C   . LYS A 1 127 ? 150.899 112.167 117.168 1.00 37.76  ? 106 LYS B C   1 
ATOM   757  O O   . LYS A 1 127 ? 151.969 112.034 116.564 1.00 38.18  ? 106 LYS B O   1 
ATOM   758  C CB  . LYS A 1 127 ? 149.554 114.261 116.922 1.00 41.45  ? 106 LYS B CB  1 
ATOM   759  C CG  . LYS A 1 127 ? 150.877 114.952 117.200 1.00 37.15  ? 106 LYS B CG  1 
ATOM   760  C CD  . LYS A 1 127 ? 150.740 116.459 117.177 1.00 39.39  ? 106 LYS B CD  1 
ATOM   761  C CE  . LYS A 1 127 ? 151.504 117.090 118.322 1.00 41.48  ? 106 LYS B CE  1 
ATOM   762  N NZ  . LYS A 1 127 ? 150.796 116.905 119.616 1.00 46.02  ? 106 LYS B NZ  1 
ATOM   763  N N   . LEU A 1 128 ? 150.742 111.761 118.427 1.00 35.76  ? 107 LEU B N   1 
ATOM   764  C CA  . LEU A 1 128 ? 151.881 111.375 119.251 1.00 40.43  ? 107 LEU B CA  1 
ATOM   765  C C   . LEU A 1 128 ? 152.292 109.920 119.077 1.00 42.18  ? 107 LEU B C   1 
ATOM   766  O O   . LEU A 1 128 ? 153.489 109.616 119.130 1.00 41.63  ? 107 LEU B O   1 
ATOM   767  C CB  . LEU A 1 128 ? 151.573 111.650 120.724 1.00 38.65  ? 107 LEU B CB  1 
ATOM   768  C CG  . LEU A 1 128 ? 151.515 113.138 121.073 1.00 34.74  ? 107 LEU B CG  1 
ATOM   769  C CD1 . LEU A 1 128 ? 150.743 113.370 122.358 1.00 34.02  ? 107 LEU B CD1 1 
ATOM   770  C CD2 . LEU A 1 128 ? 152.914 113.715 121.165 1.00 35.06  ? 107 LEU B CD2 1 
ATOM   771  N N   . GLY A 1 129 ? 151.337 109.010 118.881 1.00 45.80  ? 108 GLY B N   1 
ATOM   772  C CA  . GLY A 1 129 ? 151.646 107.620 118.626 1.00 42.60  ? 108 GLY B CA  1 
ATOM   773  C C   . GLY A 1 129 ? 150.970 106.698 119.627 1.00 47.80  ? 108 GLY B C   1 
ATOM   774  O O   . GLY A 1 129 ? 149.940 107.042 120.218 1.00 45.39  ? 108 GLY B O   1 
ATOM   775  N N   . GLU A 1 130 ? 151.566 105.520 119.806 1.00 52.72  ? 109 GLU B N   1 
ATOM   776  C CA  . GLU A 1 130 ? 151.005 104.482 120.658 1.00 51.18  ? 109 GLU B CA  1 
ATOM   777  C C   . GLU A 1 130 ? 151.411 104.614 122.119 1.00 51.09  ? 109 GLU B C   1 
ATOM   778  O O   . GLU A 1 130 ? 150.863 103.897 122.962 1.00 54.61  ? 109 GLU B O   1 
ATOM   779  C CB  . GLU A 1 130 ? 151.416 103.099 120.143 1.00 43.49  ? 109 GLU B CB  1 
ATOM   780  N N   . HIS A 1 131 ? 152.348 105.501 122.442 1.00 45.34  ? 110 HIS B N   1 
ATOM   781  C CA  . HIS A 1 131 ? 152.766 105.712 123.820 1.00 41.58  ? 110 HIS B CA  1 
ATOM   782  C C   . HIS A 1 131 ? 151.956 106.790 124.525 1.00 39.98  ? 110 HIS B C   1 
ATOM   783  O O   . HIS A 1 131 ? 152.190 107.044 125.709 1.00 42.79  ? 110 HIS B O   1 
ATOM   784  C CB  . HIS A 1 131 ? 154.253 106.072 123.872 1.00 43.35  ? 110 HIS B CB  1 
ATOM   785  C CG  . HIS A 1 131 ? 155.163 104.933 123.534 1.00 46.28  ? 110 HIS B CG  1 
ATOM   786  N ND1 . HIS A 1 131 ? 154.716 103.637 123.400 1.00 45.45  ? 110 HIS B ND1 1 
ATOM   787  C CD2 . HIS A 1 131 ? 156.497 104.896 123.307 1.00 47.66  ? 110 HIS B CD2 1 
ATOM   788  C CE1 . HIS A 1 131 ? 155.735 102.851 123.102 1.00 46.15  ? 110 HIS B CE1 1 
ATOM   789  N NE2 . HIS A 1 131 ? 156.828 103.590 123.041 1.00 50.80  ? 110 HIS B NE2 1 
ATOM   790  N N   . ALA A 1 132 ? 151.016 107.425 123.836 1.00 40.86  ? 111 ALA B N   1 
ATOM   791  C CA  . ALA A 1 132 ? 150.191 108.469 124.427 1.00 40.95  ? 111 ALA B CA  1 
ATOM   792  C C   . ALA A 1 132 ? 148.941 107.838 125.022 1.00 43.04  ? 111 ALA B C   1 
ATOM   793  O O   . ALA A 1 132 ? 148.173 107.184 124.309 1.00 49.54  ? 111 ALA B O   1 
ATOM   794  C CB  . ALA A 1 132 ? 149.816 109.519 123.383 1.00 37.45  ? 111 ALA B CB  1 
ATOM   795  N N   . TYR A 1 133 ? 148.738 108.032 126.323 1.00 37.54  ? 112 TYR B N   1 
ATOM   796  C CA  . TYR A 1 133 ? 147.578 107.482 126.995 1.00 28.06  ? 112 TYR B CA  1 
ATOM   797  C C   . TYR A 1 133 ? 146.729 108.601 127.578 1.00 35.30  ? 112 TYR B C   1 
ATOM   798  O O   . TYR A 1 133 ? 147.269 109.584 128.095 1.00 44.27  ? 112 TYR B O   1 
ATOM   799  C CB  . TYR A 1 133 ? 147.995 106.515 128.110 1.00 23.41  ? 112 TYR B CB  1 
ATOM   800  C CG  . TYR A 1 133 ? 148.861 105.383 127.617 1.00 36.26  ? 112 TYR B CG  1 
ATOM   801  C CD1 . TYR A 1 133 ? 148.298 104.224 127.109 1.00 35.42  ? 112 TYR B CD1 1 
ATOM   802  C CD2 . TYR A 1 133 ? 150.245 105.479 127.649 1.00 40.52  ? 112 TYR B CD2 1 
ATOM   803  C CE1 . TYR A 1 133 ? 149.088 103.189 126.651 1.00 41.75  ? 112 TYR B CE1 1 
ATOM   804  C CE2 . TYR A 1 133 ? 151.043 104.451 127.194 1.00 39.94  ? 112 TYR B CE2 1 
ATOM   805  C CZ  . TYR A 1 133 ? 150.460 103.308 126.696 1.00 44.95  ? 112 TYR B CZ  1 
ATOM   806  O OH  . TYR A 1 133 ? 151.252 102.279 126.242 1.00 39.26  ? 112 TYR B OH  1 
ATOM   807  N N   . PRO A 1 134 ? 145.411 108.489 127.508 1.00 24.41  ? 113 PRO B N   1 
ATOM   808  C CA  . PRO A 1 134 ? 144.546 109.584 127.942 1.00 19.42  ? 113 PRO B CA  1 
ATOM   809  C C   . PRO A 1 134 ? 144.191 109.521 129.417 1.00 21.90  ? 113 PRO B C   1 
ATOM   810  O O   . PRO A 1 134 ? 144.100 108.457 130.029 1.00 38.79  ? 113 PRO B O   1 
ATOM   811  C CB  . PRO A 1 134 ? 143.294 109.374 127.083 1.00 24.92  ? 113 PRO B CB  1 
ATOM   812  C CG  . PRO A 1 134 ? 143.217 107.892 126.951 1.00 33.02  ? 113 PRO B CG  1 
ATOM   813  C CD  . PRO A 1 134 ? 144.642 107.388 126.907 1.00 29.60  ? 113 PRO B CD  1 
ATOM   814  N N   . PHE A 1 135 ? 143.988 110.705 129.983 1.00 19.93  ? 114 PHE B N   1 
ATOM   815  C CA  . PHE A 1 135 ? 143.415 110.858 131.308 1.00 19.58  ? 114 PHE B CA  1 
ATOM   816  C C   . PHE A 1 135 ? 142.296 111.881 131.227 1.00 22.41  ? 114 PHE B C   1 
ATOM   817  O O   . PHE A 1 135 ? 142.309 112.763 130.367 1.00 37.85  ? 114 PHE B O   1 
ATOM   818  C CB  . PHE A 1 135 ? 144.461 111.288 132.352 1.00 21.01  ? 114 PHE B CB  1 
ATOM   819  C CG  . PHE A 1 135 ? 144.992 112.685 132.161 1.00 10.23  ? 114 PHE B CG  1 
ATOM   820  C CD1 . PHE A 1 135 ? 144.328 113.778 132.689 1.00 13.33  ? 114 PHE B CD1 1 
ATOM   821  C CD2 . PHE A 1 135 ? 146.179 112.896 131.491 1.00 15.08  ? 114 PHE B CD2 1 
ATOM   822  C CE1 . PHE A 1 135 ? 144.821 115.050 132.521 1.00 10.79  ? 114 PHE B CE1 1 
ATOM   823  C CE2 . PHE A 1 135 ? 146.676 114.167 131.325 1.00 15.19  ? 114 PHE B CE2 1 
ATOM   824  C CZ  . PHE A 1 135 ? 145.996 115.244 131.840 1.00 13.68  ? 114 PHE B CZ  1 
ATOM   825  N N   . THR A 1 136 ? 141.320 111.750 132.118 1.00 21.82  ? 115 THR B N   1 
ATOM   826  C CA  . THR A 1 136 ? 140.222 112.701 132.154 1.00 21.76  ? 115 THR B CA  1 
ATOM   827  C C   . THR A 1 136 ? 139.642 112.742 133.558 1.00 22.92  ? 115 THR B C   1 
ATOM   828  O O   . THR A 1 136 ? 139.508 111.708 134.217 1.00 30.22  ? 115 THR B O   1 
ATOM   829  C CB  . THR A 1 136 ? 139.142 112.351 131.122 1.00 25.77  ? 115 THR B CB  1 
ATOM   830  O OG1 . THR A 1 136 ? 138.060 113.285 131.219 1.00 28.38  ? 115 THR B OG1 1 
ATOM   831  C CG2 . THR A 1 136 ? 138.619 110.940 131.334 1.00 28.92  ? 115 THR B CG2 1 
ATOM   832  N N   . PHE A 1 137 ? 139.315 113.947 134.011 1.00 25.17  ? 116 PHE B N   1 
ATOM   833  C CA  . PHE A 1 137 ? 138.733 114.172 135.322 1.00 28.38  ? 116 PHE B CA  1 
ATOM   834  C C   . PHE A 1 137 ? 137.350 114.787 135.167 1.00 30.88  ? 116 PHE B C   1 
ATOM   835  O O   . PHE A 1 137 ? 136.998 115.326 134.116 1.00 29.12  ? 116 PHE B O   1 
ATOM   836  C CB  . PHE A 1 137 ? 139.619 115.086 136.179 1.00 19.66  ? 116 PHE B CB  1 
ATOM   837  C CG  . PHE A 1 137 ? 140.983 114.524 136.458 1.00 27.26  ? 116 PHE B CG  1 
ATOM   838  C CD1 . PHE A 1 137 ? 141.143 113.456 137.319 1.00 19.99  ? 116 PHE B CD1 1 
ATOM   839  C CD2 . PHE A 1 137 ? 142.104 115.068 135.863 1.00 30.57  ? 116 PHE B CD2 1 
ATOM   840  C CE1 . PHE A 1 137 ? 142.391 112.942 137.575 1.00 18.80  ? 116 PHE B CE1 1 
ATOM   841  C CE2 . PHE A 1 137 ? 143.356 114.555 136.117 1.00 21.43  ? 116 PHE B CE2 1 
ATOM   842  C CZ  . PHE A 1 137 ? 143.498 113.492 136.974 1.00 16.99  ? 116 PHE B CZ  1 
ATOM   843  N N   . GLU A 1 138 ? 136.557 114.686 136.230 1.00 34.37  ? 117 GLU B N   1 
ATOM   844  C CA  . GLU A 1 138 ? 135.228 115.300 136.281 1.00 32.38  ? 117 GLU B CA  1 
ATOM   845  C C   . GLU A 1 138 ? 135.126 116.002 137.632 1.00 32.20  ? 117 GLU B C   1 
ATOM   846  O O   . GLU A 1 138 ? 134.728 115.396 138.630 1.00 37.15  ? 117 GLU B O   1 
ATOM   847  C CB  . GLU A 1 138 ? 134.124 114.270 136.090 1.00 37.73  ? 117 GLU B CB  1 
ATOM   848  N N   . ILE A 1 139 ? 135.496 117.278 137.654 1.00 32.19  ? 118 ILE B N   1 
ATOM   849  C CA  . ILE A 1 139 ? 135.492 118.066 138.882 1.00 38.03  ? 118 ILE B CA  1 
ATOM   850  C C   . ILE A 1 139 ? 134.061 118.165 139.392 1.00 38.95  ? 118 ILE B C   1 
ATOM   851  O O   . ILE A 1 139 ? 133.171 118.616 138.656 1.00 36.27  ? 118 ILE B O   1 
ATOM   852  C CB  . ILE A 1 139 ? 136.099 119.458 138.650 1.00 31.54  ? 118 ILE B CB  1 
ATOM   853  C CG1 . ILE A 1 139 ? 137.607 119.352 138.438 1.00 31.47  ? 118 ILE B CG1 1 
ATOM   854  C CG2 . ILE A 1 139 ? 135.790 120.370 139.817 1.00 33.46  ? 118 ILE B CG2 1 
ATOM   855  C CD1 . ILE A 1 139 ? 138.311 120.685 138.424 1.00 30.97  ? 118 ILE B CD1 1 
ATOM   856  N N   . PRO A 1 140 ? 133.787 117.749 140.630 1.00 41.08  ? 119 PRO B N   1 
ATOM   857  C CA  . PRO A 1 140 ? 132.417 117.800 141.123 1.00 39.31  ? 119 PRO B CA  1 
ATOM   858  C C   . PRO A 1 140 ? 131.967 119.236 141.306 1.00 42.35  ? 119 PRO B C   1 
ATOM   859  O O   . PRO A 1 140 ? 132.792 120.134 141.548 1.00 43.49  ? 119 PRO B O   1 
ATOM   860  C CB  . PRO A 1 140 ? 132.500 117.061 142.470 1.00 36.19  ? 119 PRO B CB  1 
ATOM   861  C CG  . PRO A 1 140 ? 133.901 117.261 142.906 1.00 36.01  ? 119 PRO B CG  1 
ATOM   862  C CD  . PRO A 1 140 ? 134.726 117.254 141.651 1.00 40.91  ? 119 PRO B CD  1 
ATOM   863  N N   . PRO A 1 141 ? 130.670 119.505 141.196 1.00 49.29  ? 120 PRO B N   1 
ATOM   864  C CA  . PRO A 1 141 ? 130.175 120.856 141.485 1.00 46.88  ? 120 PRO B CA  1 
ATOM   865  C C   . PRO A 1 141 ? 130.310 121.188 142.962 1.00 49.83  ? 120 PRO B C   1 
ATOM   866  O O   . PRO A 1 141 ? 130.786 120.361 143.745 1.00 51.87  ? 120 PRO B O   1 
ATOM   867  C CB  . PRO A 1 141 ? 128.708 120.794 141.047 1.00 48.14  ? 120 PRO B CB  1 
ATOM   868  C CG  . PRO A 1 141 ? 128.351 119.353 141.148 1.00 45.48  ? 120 PRO B CG  1 
ATOM   869  C CD  . PRO A 1 141 ? 129.590 118.598 140.774 1.00 47.55  ? 120 PRO B CD  1 
ATOM   870  N N   . ASN A 1 142 ? 129.883 122.388 143.353 1.00 44.19  ? 121 ASN B N   1 
ATOM   871  C CA  . ASN A 1 142 ? 130.057 122.878 144.721 1.00 47.02  ? 121 ASN B CA  1 
ATOM   872  C C   . ASN A 1 142 ? 131.525 122.837 145.135 1.00 44.43  ? 121 ASN B C   1 
ATOM   873  O O   . ASN A 1 142 ? 131.864 122.431 146.246 1.00 51.20  ? 121 ASN B O   1 
ATOM   874  C CB  . ASN A 1 142 ? 129.195 122.097 145.717 1.00 48.28  ? 121 ASN B CB  1 
ATOM   875  C CG  . ASN A 1 142 ? 127.930 121.551 145.094 1.00 56.52  ? 121 ASN B CG  1 
ATOM   876  O OD1 . ASN A 1 142 ? 127.737 120.338 145.017 1.00 53.63  ? 121 ASN B OD1 1 
ATOM   877  N ND2 . ASN A 1 142 ? 127.060 122.445 144.640 1.00 53.93  ? 121 ASN B ND2 1 
ATOM   878  N N   . LEU A 1 143 ? 132.403 123.255 144.233 1.00 32.01  ? 122 LEU B N   1 
ATOM   879  C CA  . LEU A 1 143 ? 133.824 123.356 144.508 1.00 24.33  ? 122 LEU B CA  1 
ATOM   880  C C   . LEU A 1 143 ? 134.277 124.786 144.265 1.00 23.28  ? 122 LEU B C   1 
ATOM   881  O O   . LEU A 1 143 ? 133.726 125.474 143.401 1.00 29.99  ? 122 LEU B O   1 
ATOM   882  C CB  . LEU A 1 143 ? 134.635 122.394 143.626 1.00 27.87  ? 122 LEU B CB  1 
ATOM   883  C CG  . LEU A 1 143 ? 134.921 121.002 144.195 1.00 33.37  ? 122 LEU B CG  1 
ATOM   884  C CD1 . LEU A 1 143 ? 136.017 120.320 143.407 1.00 31.20  ? 122 LEU B CD1 1 
ATOM   885  C CD2 . LEU A 1 143 ? 135.301 121.075 145.663 1.00 35.24  ? 122 LEU B CD2 1 
ATOM   886  N N   . PRO A 1 144 ? 135.266 125.264 145.016 1.00 24.64  ? 123 PRO B N   1 
ATOM   887  C CA  . PRO A 1 144 ? 135.663 126.669 144.896 1.00 18.55  ? 123 PRO B CA  1 
ATOM   888  C C   . PRO A 1 144 ? 136.268 126.978 143.538 1.00 15.58  ? 123 PRO B C   1 
ATOM   889  O O   . PRO A 1 144 ? 136.920 126.139 142.912 1.00 25.83  ? 123 PRO B O   1 
ATOM   890  C CB  . PRO A 1 144 ? 136.704 126.844 146.010 1.00 17.67  ? 123 PRO B CB  1 
ATOM   891  C CG  . PRO A 1 144 ? 136.594 125.627 146.862 1.00 17.81  ? 123 PRO B CG  1 
ATOM   892  C CD  . PRO A 1 144 ? 136.101 124.541 145.986 1.00 20.58  ? 123 PRO B CD  1 
ATOM   893  N N   . CYS A 1 145 ? 136.043 128.205 143.084 1.00 12.19  ? 124 CYS B N   1 
ATOM   894  C CA  . CYS A 1 145 ? 136.740 128.700 141.910 1.00 7.73   ? 124 CYS B CA  1 
ATOM   895  C C   . CYS A 1 145 ? 138.113 129.230 142.307 1.00 12.49  ? 124 CYS B C   1 
ATOM   896  O O   . CYS A 1 145 ? 138.386 129.509 143.475 1.00 34.49  ? 124 CYS B O   1 
ATOM   897  C CB  . CYS A 1 145 ? 135.924 129.789 141.216 1.00 17.20  ? 124 CYS B CB  1 
ATOM   898  S SG  . CYS A 1 145 ? 134.416 129.190 140.426 1.00 42.05  ? 124 CYS B SG  1 
ATOM   899  N N   . SER A 1 146 ? 138.986 129.360 141.316 1.00 12.49  ? 125 SER B N   1 
ATOM   900  C CA  . SER A 1 146 ? 140.355 129.794 141.569 1.00 13.27  ? 125 SER B CA  1 
ATOM   901  C C   . SER A 1 146 ? 140.348 131.237 142.056 1.00 10.70  ? 125 SER B C   1 
ATOM   902  O O   . SER A 1 146 ? 140.070 132.160 141.285 1.00 34.81  ? 125 SER B O   1 
ATOM   903  C CB  . SER A 1 146 ? 141.197 129.642 140.307 1.00 22.16  ? 125 SER B CB  1 
ATOM   904  O OG  . SER A 1 146 ? 141.545 128.288 140.089 1.00 15.15  ? 125 SER B OG  1 
ATOM   905  N N   . VAL A 1 147 ? 140.649 131.434 143.336 1.00 9.09   ? 126 VAL B N   1 
ATOM   906  C CA  . VAL A 1 147 ? 140.667 132.752 143.959 1.00 16.41  ? 126 VAL B CA  1 
ATOM   907  C C   . VAL A 1 147 ? 142.035 132.957 144.584 1.00 13.35  ? 126 VAL B C   1 
ATOM   908  O O   . VAL A 1 147 ? 142.536 132.077 145.290 1.00 30.39  ? 126 VAL B O   1 
ATOM   909  C CB  . VAL A 1 147 ? 139.564 132.906 145.024 1.00 5.24   ? 126 VAL B CB  1 
ATOM   910  C CG1 . VAL A 1 147 ? 139.671 134.251 145.700 1.00 6.06   ? 126 VAL B CG1 1 
ATOM   911  C CG2 . VAL A 1 147 ? 138.190 132.738 144.404 1.00 17.21  ? 126 VAL B CG2 1 
ATOM   912  N N   . THR A 1 148 ? 142.641 134.107 144.321 1.00 11.57  ? 127 THR B N   1 
ATOM   913  C CA  . THR A 1 148 ? 143.922 134.471 144.905 1.00 10.25  ? 127 THR B CA  1 
ATOM   914  C C   . THR A 1 148 ? 143.715 135.610 145.890 1.00 22.06  ? 127 THR B C   1 
ATOM   915  O O   . THR A 1 148 ? 143.108 136.629 145.549 1.00 29.29  ? 127 THR B O   1 
ATOM   916  C CB  . THR A 1 148 ? 144.924 134.883 143.825 1.00 19.31  ? 127 THR B CB  1 
ATOM   917  O OG1 . THR A 1 148 ? 145.290 133.736 143.052 1.00 22.55  ? 127 THR B OG1 1 
ATOM   918  C CG2 . THR A 1 148 ? 146.170 135.476 144.453 1.00 20.35  ? 127 THR B CG2 1 
ATOM   919  N N   . LEU A 1 149 ? 144.203 135.428 147.112 1.00 28.21  ? 128 LEU B N   1 
ATOM   920  C CA  . LEU A 1 149 ? 144.189 136.485 148.110 1.00 17.86  ? 128 LEU B CA  1 
ATOM   921  C C   . LEU A 1 149 ? 145.429 137.347 147.928 1.00 24.67  ? 128 LEU B C   1 
ATOM   922  O O   . LEU A 1 149 ? 146.546 136.828 147.861 1.00 34.56  ? 128 LEU B O   1 
ATOM   923  C CB  . LEU A 1 149 ? 144.145 135.899 149.520 1.00 21.07  ? 128 LEU B CB  1 
ATOM   924  C CG  . LEU A 1 149 ? 142.872 135.135 149.881 1.00 23.69  ? 128 LEU B CG  1 
ATOM   925  C CD1 . LEU A 1 149 ? 142.787 134.931 151.377 1.00 32.07  ? 128 LEU B CD1 1 
ATOM   926  C CD2 . LEU A 1 149 ? 141.643 135.861 149.369 1.00 23.14  ? 128 LEU B CD2 1 
ATOM   927  N N   . GLN A 1 150 ? 145.228 138.654 147.843 1.00 29.18  ? 129 GLN B N   1 
ATOM   928  C CA  . GLN A 1 150 ? 146.329 139.563 147.567 1.00 33.49  ? 129 GLN B CA  1 
ATOM   929  C C   . GLN A 1 150 ? 147.351 139.502 148.695 1.00 38.31  ? 129 GLN B C   1 
ATOM   930  O O   . GLN A 1 150 ? 147.000 139.764 149.855 1.00 40.69  ? 129 GLN B O   1 
ATOM   931  C CB  . GLN A 1 150 ? 145.814 140.988 147.401 1.00 34.60  ? 129 GLN B CB  1 
ATOM   932  C CG  . GLN A 1 150 ? 146.879 141.982 146.992 1.00 34.13  ? 129 GLN B CG  1 
ATOM   933  C CD  . GLN A 1 150 ? 146.311 143.164 146.242 1.00 35.81  ? 129 GLN B CD  1 
ATOM   934  O OE1 . GLN A 1 150 ? 145.320 143.761 146.660 1.00 28.90  ? 129 GLN B OE1 1 
ATOM   935  N NE2 . GLN A 1 150 ? 146.934 143.507 145.124 1.00 34.51  ? 129 GLN B NE2 1 
ATOM   936  N N   . PRO A 1 151 ? 148.604 139.160 148.413 1.00 51.63  ? 130 PRO B N   1 
ATOM   937  C CA  . PRO A 1 151 ? 149.605 139.101 149.480 1.00 49.47  ? 130 PRO B CA  1 
ATOM   938  C C   . PRO A 1 151 ? 149.936 140.485 150.009 1.00 54.53  ? 130 PRO B C   1 
ATOM   939  O O   . PRO A 1 151 ? 149.838 141.491 149.302 1.00 51.98  ? 130 PRO B O   1 
ATOM   940  C CB  . PRO A 1 151 ? 150.817 138.460 148.795 1.00 49.89  ? 130 PRO B CB  1 
ATOM   941  C CG  . PRO A 1 151 ? 150.641 138.775 147.352 1.00 52.33  ? 130 PRO B CG  1 
ATOM   942  C CD  . PRO A 1 151 ? 149.162 138.777 147.105 1.00 51.93  ? 130 PRO B CD  1 
ATOM   943  N N   . GLY A 1 152 ? 150.326 140.526 151.275 1.00 67.15  ? 131 GLY B N   1 
ATOM   944  C CA  . GLY A 1 152 ? 150.786 141.751 151.880 1.00 66.97  ? 131 GLY B CA  1 
ATOM   945  C C   . GLY A 1 152 ? 152.222 142.050 151.515 1.00 71.13  ? 131 GLY B C   1 
ATOM   946  O O   . GLY A 1 152 ? 152.923 141.254 150.871 1.00 67.88  ? 131 GLY B O   1 
ATOM   947  N N   . PRO A 1 153 ? 152.685 143.234 151.919 1.00 79.33  ? 132 PRO B N   1 
ATOM   948  C CA  . PRO A 1 153 ? 154.089 143.594 151.666 1.00 76.87  ? 132 PRO B CA  1 
ATOM   949  C C   . PRO A 1 153 ? 155.082 142.705 152.393 1.00 78.44  ? 132 PRO B C   1 
ATOM   950  O O   . PRO A 1 153 ? 156.247 142.637 151.981 1.00 77.88  ? 132 PRO B O   1 
ATOM   951  C CB  . PRO A 1 153 ? 154.172 145.046 152.154 1.00 78.66  ? 132 PRO B CB  1 
ATOM   952  C CG  . PRO A 1 153 ? 153.061 145.175 153.140 1.00 76.73  ? 132 PRO B CG  1 
ATOM   953  C CD  . PRO A 1 153 ? 151.959 144.294 152.636 1.00 77.47  ? 132 PRO B CD  1 
ATOM   954  N N   . GLU A 1 154 ? 154.662 142.023 153.459 1.00 84.54  ? 133 GLU B N   1 
ATOM   955  C CA  . GLU A 1 154 ? 155.540 141.147 154.224 1.00 83.64  ? 133 GLU B CA  1 
ATOM   956  C C   . GLU A 1 154 ? 155.112 139.687 154.157 1.00 82.16  ? 133 GLU B C   1 
ATOM   957  O O   . GLU A 1 154 ? 155.609 138.871 154.942 1.00 82.97  ? 133 GLU B O   1 
ATOM   958  C CB  . GLU A 1 154 ? 155.606 141.606 155.683 1.00 82.22  ? 133 GLU B CB  1 
ATOM   959  N N   . ASP A 1 155 ? 154.207 139.333 153.247 1.00 83.81  ? 134 ASP B N   1 
ATOM   960  C CA  . ASP A 1 155 ? 153.748 137.954 153.098 1.00 84.26  ? 134 ASP B CA  1 
ATOM   961  C C   . ASP A 1 155 ? 154.671 137.249 152.112 1.00 87.05  ? 134 ASP B C   1 
ATOM   962  O O   . ASP A 1 155 ? 154.573 137.447 150.899 1.00 85.93  ? 134 ASP B O   1 
ATOM   963  C CB  . ASP A 1 155 ? 152.296 137.916 152.634 1.00 81.38  ? 134 ASP B CB  1 
ATOM   964  N N   . THR A 1 156 ? 155.575 136.423 152.635 1.00 89.38  ? 135 THR B N   1 
ATOM   965  C CA  . THR A 1 156 ? 156.551 135.703 151.825 1.00 87.03  ? 135 THR B CA  1 
ATOM   966  C C   . THR A 1 156 ? 156.132 134.240 151.739 1.00 87.37  ? 135 THR B C   1 
ATOM   967  O O   . THR A 1 156 ? 156.078 133.541 152.756 1.00 85.93  ? 135 THR B O   1 
ATOM   968  C CB  . THR A 1 156 ? 157.953 135.838 152.414 1.00 86.60  ? 135 THR B CB  1 
ATOM   969  N N   . GLY A 1 157 ? 155.843 133.783 150.532 1.00 82.90  ? 136 GLY B N   1 
ATOM   970  C CA  . GLY A 1 157 ? 155.418 132.417 150.311 1.00 82.74  ? 136 GLY B CA  1 
ATOM   971  C C   . GLY A 1 157 ? 154.390 132.365 149.200 1.00 81.84  ? 136 GLY B C   1 
ATOM   972  O O   . GLY A 1 157 ? 154.104 133.364 148.546 1.00 80.60  ? 136 GLY B O   1 
ATOM   973  N N   . LYS A 1 158 ? 153.841 131.171 148.998 1.00 65.41  ? 137 LYS B N   1 
ATOM   974  C CA  . LYS A 1 158 ? 152.788 130.996 148.007 1.00 62.39  ? 137 LYS B CA  1 
ATOM   975  C C   . LYS A 1 158 ? 151.540 131.761 148.427 1.00 65.33  ? 137 LYS B C   1 
ATOM   976  O O   . LYS A 1 158 ? 151.140 131.738 149.595 1.00 65.56  ? 137 LYS B O   1 
ATOM   977  C CB  . LYS A 1 158 ? 152.465 129.515 147.826 1.00 62.66  ? 137 LYS B CB  1 
ATOM   978  N N   . ALA A 1 159 ? 150.924 132.441 147.464 1.00 61.29  ? 138 ALA B N   1 
ATOM   979  C CA  . ALA A 1 159 ? 149.771 133.279 147.761 1.00 58.64  ? 138 ALA B CA  1 
ATOM   980  C C   . ALA A 1 159 ? 148.607 132.436 148.262 1.00 57.09  ? 138 ALA B C   1 
ATOM   981  O O   . ALA A 1 159 ? 148.369 131.325 147.784 1.00 56.71  ? 138 ALA B O   1 
ATOM   982  C CB  . ALA A 1 159 ? 149.354 134.067 146.520 1.00 57.11  ? 138 ALA B CB  1 
ATOM   983  N N   . CYS A 1 160 ? 147.886 132.971 149.241 1.00 43.76  ? 139 CYS B N   1 
ATOM   984  C CA  . CYS A 1 160 ? 146.746 132.272 149.805 1.00 44.17  ? 139 CYS B CA  1 
ATOM   985  C C   . CYS A 1 160 ? 145.590 132.242 148.811 1.00 42.50  ? 139 CYS B C   1 
ATOM   986  O O   . CYS A 1 160 ? 145.486 133.077 147.910 1.00 50.28  ? 139 CYS B O   1 
ATOM   987  C CB  . CYS A 1 160 ? 146.304 132.940 151.106 1.00 46.70  ? 139 CYS B CB  1 
ATOM   988  S SG  . CYS A 1 160 ? 147.448 132.699 152.484 1.00 68.44  ? 139 CYS B SG  1 
ATOM   989  N N   . GLY A 1 161 ? 144.717 131.255 148.979 1.00 25.88  ? 140 GLY B N   1 
ATOM   990  C CA  . GLY A 1 161 ? 143.537 131.132 148.158 1.00 17.82  ? 140 GLY B CA  1 
ATOM   991  C C   . GLY A 1 161 ? 143.360 129.713 147.680 1.00 26.17  ? 140 GLY B C   1 
ATOM   992  O O   . GLY A 1 161 ? 143.965 128.776 148.211 1.00 41.83  ? 140 GLY B O   1 
ATOM   993  N N   . VAL A 1 162 ? 142.524 129.558 146.660 1.00 22.76  ? 141 VAL B N   1 
ATOM   994  C CA  . VAL A 1 162 ? 142.190 128.258 146.091 1.00 13.19  ? 141 VAL B CA  1 
ATOM   995  C C   . VAL A 1 162 ? 142.980 128.075 144.804 1.00 12.77  ? 141 VAL B C   1 
ATOM   996  O O   . VAL A 1 162 ? 143.027 128.977 143.961 1.00 26.69  ? 141 VAL B O   1 
ATOM   997  C CB  . VAL A 1 162 ? 140.680 128.141 145.831 1.00 14.92  ? 141 VAL B CB  1 
ATOM   998  C CG1 . VAL A 1 162 ? 140.361 126.813 145.183 1.00 14.17  ? 141 VAL B CG1 1 
ATOM   999  C CG2 . VAL A 1 162 ? 139.911 128.312 147.125 1.00 14.46  ? 141 VAL B CG2 1 
ATOM   1000 N N   . ASP A 1 163 ? 143.609 126.913 144.657 1.00 18.05  ? 142 ASP B N   1 
ATOM   1001 C CA  . ASP A 1 163 ? 144.442 126.617 143.503 1.00 5.07   ? 142 ASP B CA  1 
ATOM   1002 C C   . ASP A 1 163 ? 144.210 125.183 143.061 1.00 15.02  ? 142 ASP B C   1 
ATOM   1003 O O   . ASP A 1 163 ? 144.129 124.276 143.892 1.00 20.36  ? 142 ASP B O   1 
ATOM   1004 C CB  . ASP A 1 163 ? 145.924 126.827 143.821 1.00 11.25  ? 142 ASP B CB  1 
ATOM   1005 C CG  . ASP A 1 163 ? 146.781 126.892 142.578 1.00 29.84  ? 142 ASP B CG  1 
ATOM   1006 O OD1 . ASP A 1 163 ? 146.387 127.593 141.623 1.00 38.66  ? 142 ASP B OD1 1 
ATOM   1007 O OD2 . ASP A 1 163 ? 147.847 126.241 142.552 1.00 33.75  ? 142 ASP B OD2 1 
ATOM   1008 N N   . TYR A 1 164 ? 144.109 124.984 141.753 1.00 18.56  ? 143 TYR B N   1 
ATOM   1009 C CA  . TYR A 1 164 ? 143.999 123.662 141.159 1.00 1.49   ? 143 TYR B CA  1 
ATOM   1010 C C   . TYR A 1 164 ? 145.311 123.306 140.478 1.00 2.11   ? 143 TYR B C   1 
ATOM   1011 O O   . TYR A 1 164 ? 146.073 124.185 140.071 1.00 23.85  ? 143 TYR B O   1 
ATOM   1012 C CB  . TYR A 1 164 ? 142.851 123.600 140.151 1.00 4.03   ? 143 TYR B CB  1 
ATOM   1013 C CG  . TYR A 1 164 ? 141.486 123.723 140.778 1.00 2.03   ? 143 TYR B CG  1 
ATOM   1014 C CD1 . TYR A 1 164 ? 140.991 124.956 141.165 1.00 3.74   ? 143 TYR B CD1 1 
ATOM   1015 C CD2 . TYR A 1 164 ? 140.692 122.609 140.980 1.00 10.04  ? 143 TYR B CD2 1 
ATOM   1016 C CE1 . TYR A 1 164 ? 139.750 125.078 141.736 1.00 4.90   ? 143 TYR B CE1 1 
ATOM   1017 C CE2 . TYR A 1 164 ? 139.449 122.721 141.555 1.00 17.83  ? 143 TYR B CE2 1 
ATOM   1018 C CZ  . TYR A 1 164 ? 138.983 123.960 141.930 1.00 10.85  ? 143 TYR B CZ  1 
ATOM   1019 O OH  . TYR A 1 164 ? 137.742 124.081 142.501 1.00 22.58  ? 143 TYR B OH  1 
ATOM   1020 N N   . GLU A 1 165 ? 145.583 122.010 140.372 1.00 6.62   ? 144 GLU B N   1 
ATOM   1021 C CA  . GLU A 1 165 ? 146.825 121.565 139.760 1.00 6.42   ? 144 GLU B CA  1 
ATOM   1022 C C   . GLU A 1 165 ? 146.663 120.142 139.250 1.00 8.47   ? 144 GLU B C   1 
ATOM   1023 O O   . GLU A 1 165 ? 146.045 119.306 139.911 1.00 15.23  ? 144 GLU B O   1 
ATOM   1024 C CB  . GLU A 1 165 ? 147.995 121.641 140.746 1.00 7.53   ? 144 GLU B CB  1 
ATOM   1025 C CG  . GLU A 1 165 ? 149.343 121.385 140.103 1.00 14.60  ? 144 GLU B CG  1 
ATOM   1026 C CD  . GLU A 1 165 ? 150.502 121.880 140.941 1.00 27.80  ? 144 GLU B CD  1 
ATOM   1027 O OE1 . GLU A 1 165 ? 150.831 123.083 140.855 1.00 21.66  ? 144 GLU B OE1 1 
ATOM   1028 O OE2 . GLU A 1 165 ? 151.089 121.065 141.682 1.00 31.67  ? 144 GLU B OE2 1 
ATOM   1029 N N   . VAL A 1 166 ? 147.230 119.882 138.077 1.00 4.83   ? 145 VAL B N   1 
ATOM   1030 C CA  . VAL A 1 166 ? 147.303 118.547 137.497 1.00 4.45   ? 145 VAL B CA  1 
ATOM   1031 C C   . VAL A 1 166 ? 148.741 118.074 137.636 1.00 9.27   ? 145 VAL B C   1 
ATOM   1032 O O   . VAL A 1 166 ? 149.672 118.772 137.219 1.00 15.34  ? 145 VAL B O   1 
ATOM   1033 C CB  . VAL A 1 166 ? 146.855 118.541 136.027 1.00 6.06   ? 145 VAL B CB  1 
ATOM   1034 C CG1 . VAL A 1 166 ? 147.439 117.350 135.296 1.00 3.96   ? 145 VAL B CG1 1 
ATOM   1035 C CG2 . VAL A 1 166 ? 145.343 118.527 135.938 1.00 13.94  ? 145 VAL B CG2 1 
ATOM   1036 N N   . LYS A 1 167 ? 148.931 116.905 138.242 1.00 7.20   ? 146 LYS B N   1 
ATOM   1037 C CA  . LYS A 1 167 ? 150.262 116.355 138.447 1.00 4.71   ? 146 LYS B CA  1 
ATOM   1038 C C   . LYS A 1 167 ? 150.317 114.924 137.942 1.00 0.99   ? 146 LYS B C   1 
ATOM   1039 O O   . LYS A 1 167 ? 149.488 114.096 138.323 1.00 17.40  ? 146 LYS B O   1 
ATOM   1040 C CB  . LYS A 1 167 ? 150.667 116.409 139.922 1.00 10.97  ? 146 LYS B CB  1 
ATOM   1041 C CG  . LYS A 1 167 ? 152.162 116.254 140.154 1.00 16.74  ? 146 LYS B CG  1 
ATOM   1042 C CD  . LYS A 1 167 ? 152.458 115.675 141.522 1.00 19.07  ? 146 LYS B CD  1 
ATOM   1043 C CE  . LYS A 1 167 ? 151.530 116.245 142.582 1.00 24.81  ? 146 LYS B CE  1 
ATOM   1044 N NZ  . LYS A 1 167 ? 151.691 115.565 143.896 1.00 27.94  ? 146 LYS B NZ  1 
ATOM   1045 N N   . ALA A 1 168 ? 151.301 114.638 137.096 1.00 5.56   ? 147 ALA B N   1 
ATOM   1046 C CA  . ALA A 1 168 ? 151.555 113.300 136.589 1.00 7.09   ? 147 ALA B CA  1 
ATOM   1047 C C   . ALA A 1 168 ? 152.955 112.873 136.993 1.00 20.17  ? 147 ALA B C   1 
ATOM   1048 O O   . ALA A 1 168 ? 153.902 113.656 136.891 1.00 32.37  ? 147 ALA B O   1 
ATOM   1049 C CB  . ALA A 1 168 ? 151.420 113.246 135.071 1.00 11.02  ? 147 ALA B CB  1 
ATOM   1050 N N   . PHE A 1 169 ? 153.089 111.632 137.454 1.00 16.43  ? 148 PHE B N   1 
ATOM   1051 C CA  . PHE A 1 169 ? 154.385 111.146 137.898 1.00 21.98  ? 148 PHE B CA  1 
ATOM   1052 C C   . PHE A 1 169 ? 154.501 109.659 137.608 1.00 26.12  ? 148 PHE B C   1 
ATOM   1053 O O   . PHE A 1 169 ? 153.502 108.948 137.495 1.00 34.31  ? 148 PHE B O   1 
ATOM   1054 C CB  . PHE A 1 169 ? 154.606 111.416 139.389 1.00 28.40  ? 148 PHE B CB  1 
ATOM   1055 C CG  . PHE A 1 169 ? 153.496 110.926 140.265 1.00 21.63  ? 148 PHE B CG  1 
ATOM   1056 C CD1 . PHE A 1 169 ? 153.470 109.615 140.707 1.00 24.90  ? 148 PHE B CD1 1 
ATOM   1057 C CD2 . PHE A 1 169 ? 152.484 111.777 140.657 1.00 24.91  ? 148 PHE B CD2 1 
ATOM   1058 C CE1 . PHE A 1 169 ? 152.454 109.164 141.513 1.00 25.44  ? 148 PHE B CE1 1 
ATOM   1059 C CE2 . PHE A 1 169 ? 151.468 111.331 141.464 1.00 29.78  ? 148 PHE B CE2 1 
ATOM   1060 C CZ  . PHE A 1 169 ? 151.452 110.023 141.892 1.00 26.06  ? 148 PHE B CZ  1 
ATOM   1061 N N   . CYS A 1 170 ? 155.745 109.199 137.499 1.00 32.88  ? 149 CYS B N   1 
ATOM   1062 C CA  . CYS A 1 170 ? 156.057 107.794 137.267 1.00 31.66  ? 149 CYS B CA  1 
ATOM   1063 C C   . CYS A 1 170 ? 156.480 107.172 138.591 1.00 37.39  ? 149 CYS B C   1 
ATOM   1064 O O   . CYS A 1 170 ? 157.568 107.459 139.098 1.00 38.69  ? 149 CYS B O   1 
ATOM   1065 C CB  . CYS A 1 170 ? 157.156 107.646 136.219 1.00 33.87  ? 149 CYS B CB  1 
ATOM   1066 S SG  . CYS A 1 170 ? 157.033 108.798 134.834 1.00 62.50  ? 149 CYS B SG  1 
ATOM   1067 N N   . ALA A 1 171 ? 155.622 106.320 139.147 1.00 38.68  ? 150 ALA B N   1 
ATOM   1068 C CA  . ALA A 1 171 ? 155.900 105.676 140.421 1.00 41.93  ? 150 ALA B CA  1 
ATOM   1069 C C   . ALA A 1 171 ? 155.316 104.273 140.412 1.00 48.63  ? 150 ALA B C   1 
ATOM   1070 O O   . ALA A 1 171 ? 154.358 103.988 139.689 1.00 48.65  ? 150 ALA B O   1 
ATOM   1071 C CB  . ALA A 1 171 ? 155.329 106.478 141.595 1.00 38.08  ? 150 ALA B CB  1 
ATOM   1072 N N   . GLU A 1 172 ? 155.909 103.394 141.224 1.00 47.67  ? 151 GLU B N   1 
ATOM   1073 C CA  . GLU A 1 172 ? 155.400 102.031 141.334 1.00 45.40  ? 151 GLU B CA  1 
ATOM   1074 C C   . GLU A 1 172 ? 154.054 102.000 142.047 1.00 47.65  ? 151 GLU B C   1 
ATOM   1075 O O   . GLU A 1 172 ? 153.176 101.204 141.695 1.00 44.02  ? 151 GLU B O   1 
ATOM   1076 C CB  . GLU A 1 172 ? 156.413 101.149 142.061 1.00 42.24  ? 151 GLU B CB  1 
ATOM   1077 N N   . ASN A 1 173 ? 153.872 102.856 143.048 1.00 48.56  ? 152 ASN B N   1 
ATOM   1078 C CA  . ASN A 1 173 ? 152.629 102.905 143.799 1.00 48.36  ? 152 ASN B CA  1 
ATOM   1079 C C   . ASN A 1 173 ? 152.356 104.345 144.207 1.00 49.51  ? 152 ASN B C   1 
ATOM   1080 O O   . ASN A 1 173 ? 153.253 105.192 144.206 1.00 51.69  ? 152 ASN B O   1 
ATOM   1081 C CB  . ASN A 1 173 ? 152.672 101.956 145.010 1.00 49.28  ? 152 ASN B CB  1 
ATOM   1082 C CG  . ASN A 1 173 ? 153.605 102.434 146.120 1.00 51.23  ? 152 ASN B CG  1 
ATOM   1083 O OD1 . ASN A 1 173 ? 153.497 103.553 146.618 1.00 49.22  ? 152 ASN B OD1 1 
ATOM   1084 N ND2 . ASN A 1 173 ? 154.533 101.569 146.511 1.00 51.09  ? 152 ASN B ND2 1 
ATOM   1085 N N   . LEU A 1 174 ? 151.094 104.614 144.549 1.00 44.99  ? 153 LEU B N   1 
ATOM   1086 C CA  . LEU A 1 174 ? 150.700 105.971 144.913 1.00 48.94  ? 153 LEU B CA  1 
ATOM   1087 C C   . LEU A 1 174 ? 151.383 106.427 146.197 1.00 51.10  ? 153 LEU B C   1 
ATOM   1088 O O   . LEU A 1 174 ? 151.749 107.601 146.328 1.00 48.25  ? 153 LEU B O   1 
ATOM   1089 C CB  . LEU A 1 174 ? 149.182 106.056 145.051 1.00 49.89  ? 153 LEU B CB  1 
ATOM   1090 C CG  . LEU A 1 174 ? 148.405 106.292 143.757 1.00 47.21  ? 153 LEU B CG  1 
ATOM   1091 C CD1 . LEU A 1 174 ? 147.017 105.688 143.850 1.00 50.57  ? 153 LEU B CD1 1 
ATOM   1092 C CD2 . LEU A 1 174 ? 148.325 107.774 143.450 1.00 43.52  ? 153 LEU B CD2 1 
ATOM   1093 N N   . GLU A 1 175 ? 151.560 105.517 147.156 1.00 56.01  ? 154 GLU B N   1 
ATOM   1094 C CA  . GLU A 1 175 ? 152.169 105.870 148.432 1.00 56.48  ? 154 GLU B CA  1 
ATOM   1095 C C   . GLU A 1 175 ? 153.662 106.146 148.326 1.00 59.15  ? 154 GLU B C   1 
ATOM   1096 O O   . GLU A 1 175 ? 154.247 106.659 149.286 1.00 58.28  ? 154 GLU B O   1 
ATOM   1097 C CB  . GLU A 1 175 ? 151.926 104.758 149.453 1.00 54.66  ? 154 GLU B CB  1 
ATOM   1098 N N   . GLU A 1 176 ? 154.291 105.826 147.198 1.00 59.42  ? 155 GLU B N   1 
ATOM   1099 C CA  . GLU A 1 176 ? 155.719 106.050 147.052 1.00 57.42  ? 155 GLU B CA  1 
ATOM   1100 C C   . GLU A 1 176 ? 156.027 107.544 146.995 1.00 61.53  ? 155 GLU B C   1 
ATOM   1101 O O   . GLU A 1 176 ? 155.168 108.375 146.689 1.00 62.22  ? 155 GLU B O   1 
ATOM   1102 C CB  . GLU A 1 176 ? 156.247 105.358 145.796 1.00 56.36  ? 155 GLU B CB  1 
ATOM   1103 N N   . LYS A 1 177 ? 157.277 107.880 147.306 1.00 66.52  ? 156 LYS B N   1 
ATOM   1104 C CA  . LYS A 1 177 ? 157.702 109.272 147.312 1.00 59.90  ? 156 LYS B CA  1 
ATOM   1105 C C   . LYS A 1 177 ? 157.691 109.837 145.898 1.00 60.57  ? 156 LYS B C   1 
ATOM   1106 O O   . LYS A 1 177 ? 158.185 109.204 144.960 1.00 62.45  ? 156 LYS B O   1 
ATOM   1107 C CB  . LYS A 1 177 ? 159.097 109.397 147.922 1.00 58.17  ? 156 LYS B CB  1 
ATOM   1108 C CG  . LYS A 1 177 ? 159.108 110.000 149.315 1.00 61.21  ? 156 LYS B CG  1 
ATOM   1109 C CD  . LYS A 1 177 ? 158.887 111.503 149.270 1.00 62.72  ? 156 LYS B CD  1 
ATOM   1110 C CE  . LYS A 1 177 ? 159.967 112.198 148.457 1.00 63.24  ? 156 LYS B CE  1 
ATOM   1111 N NZ  . LYS A 1 177 ? 159.854 113.681 148.535 1.00 59.29  ? 156 LYS B NZ  1 
ATOM   1112 N N   . ILE A 1 178 ? 157.129 111.035 145.748 1.00 54.94  ? 157 ILE B N   1 
ATOM   1113 C CA  . ILE A 1 178 ? 157.025 111.694 144.448 1.00 54.24  ? 157 ILE B CA  1 
ATOM   1114 C C   . ILE A 1 178 ? 158.373 112.350 144.164 1.00 54.68  ? 157 ILE B C   1 
ATOM   1115 O O   . ILE A 1 178 ? 158.665 113.437 144.665 1.00 55.90  ? 157 ILE B O   1 
ATOM   1116 C CB  . ILE A 1 178 ? 155.882 112.710 144.413 1.00 55.19  ? 157 ILE B CB  1 
ATOM   1117 C CG1 . ILE A 1 178 ? 154.573 112.057 144.860 1.00 54.01  ? 157 ILE B CG1 1 
ATOM   1118 C CG2 . ILE A 1 178 ? 155.733 113.298 143.023 1.00 52.11  ? 157 ILE B CG2 1 
ATOM   1119 C CD1 . ILE A 1 178 ? 154.083 112.538 146.208 1.00 54.29  ? 157 ILE B CD1 1 
ATOM   1120 N N   . HIS A 1 179 ? 159.202 111.688 143.363 1.00 53.09  ? 158 HIS B N   1 
ATOM   1121 C CA  . HIS A 1 179 ? 160.502 112.240 143.016 1.00 52.69  ? 158 HIS B CA  1 
ATOM   1122 C C   . HIS A 1 179 ? 160.336 113.461 142.121 1.00 54.24  ? 158 HIS B C   1 
ATOM   1123 O O   . HIS A 1 179 ? 159.451 113.507 141.265 1.00 58.09  ? 158 HIS B O   1 
ATOM   1124 C CB  . HIS A 1 179 ? 161.358 111.183 142.325 1.00 50.79  ? 158 HIS B CB  1 
ATOM   1125 C CG  . HIS A 1 179 ? 161.916 110.156 143.261 1.00 58.68  ? 158 HIS B CG  1 
ATOM   1126 N ND1 . HIS A 1 179 ? 162.700 110.487 144.346 1.00 57.96  ? 158 HIS B ND1 1 
ATOM   1127 C CD2 . HIS A 1 179 ? 161.798 108.808 143.280 1.00 59.31  ? 158 HIS B CD2 1 
ATOM   1128 C CE1 . HIS A 1 179 ? 163.043 109.386 144.990 1.00 56.71  ? 158 HIS B CE1 1 
ATOM   1129 N NE2 . HIS A 1 179 ? 162.509 108.353 144.364 1.00 60.01  ? 158 HIS B NE2 1 
ATOM   1130 N N   . LYS A 1 180 ? 161.195 114.459 142.332 1.00 51.80  ? 159 LYS B N   1 
ATOM   1131 C CA  . LYS A 1 180 ? 161.062 115.719 141.609 1.00 49.07  ? 159 LYS B CA  1 
ATOM   1132 C C   . LYS A 1 180 ? 161.301 115.539 140.115 1.00 46.72  ? 159 LYS B C   1 
ATOM   1133 O O   . LYS A 1 180 ? 160.616 116.161 139.295 1.00 47.11  ? 159 LYS B O   1 
ATOM   1134 C CB  . LYS A 1 180 ? 162.027 116.755 142.186 1.00 49.61  ? 159 LYS B CB  1 
ATOM   1135 C CG  . LYS A 1 180 ? 162.359 117.902 141.243 1.00 51.40  ? 159 LYS B CG  1 
ATOM   1136 C CD  . LYS A 1 180 ? 161.486 119.114 141.521 1.00 52.74  ? 159 LYS B CD  1 
ATOM   1137 C CE  . LYS A 1 180 ? 161.626 120.159 140.428 1.00 50.89  ? 159 LYS B CE  1 
ATOM   1138 N NZ  . LYS A 1 180 ? 161.480 121.539 140.962 1.00 45.71  ? 159 LYS B NZ  1 
ATOM   1139 N N   . ARG A 1 181 ? 162.264 114.694 139.743 1.00 42.95  ? 160 ARG B N   1 
ATOM   1140 C CA  . ARG A 1 181 ? 162.677 114.612 138.345 1.00 43.44  ? 160 ARG B CA  1 
ATOM   1141 C C   . ARG A 1 181 ? 161.536 114.140 137.450 1.00 44.76  ? 160 ARG B C   1 
ATOM   1142 O O   . ARG A 1 181 ? 161.238 114.768 136.430 1.00 49.03  ? 160 ARG B O   1 
ATOM   1143 C CB  . ARG A 1 181 ? 163.891 113.693 138.210 1.00 42.91  ? 160 ARG B CB  1 
ATOM   1144 C CG  . ARG A 1 181 ? 163.918 112.540 139.193 1.00 43.07  ? 160 ARG B CG  1 
ATOM   1145 C CD  . ARG A 1 181 ? 165.287 111.880 139.222 1.00 45.33  ? 160 ARG B CD  1 
ATOM   1146 N NE  . ARG A 1 181 ? 165.204 110.443 139.455 1.00 44.17  ? 160 ARG B NE  1 
ATOM   1147 C CZ  . ARG A 1 181 ? 164.894 109.884 140.617 1.00 46.23  ? 160 ARG B CZ  1 
ATOM   1148 N NH1 . ARG A 1 181 ? 164.632 110.614 141.689 1.00 49.97  ? 160 ARG B NH1 1 
ATOM   1149 N NH2 . ARG A 1 181 ? 164.846 108.558 140.707 1.00 44.12  ? 160 ARG B NH2 1 
ATOM   1150 N N   . ASN A 1 182 ? 160.879 113.040 137.814 1.00 37.56  ? 161 ASN B N   1 
ATOM   1151 C CA  . ASN A 1 182 ? 159.784 112.500 137.007 1.00 29.59  ? 161 ASN B CA  1 
ATOM   1152 C C   . ASN A 1 182 ? 158.458 112.943 137.618 1.00 28.88  ? 161 ASN B C   1 
ATOM   1153 O O   . ASN A 1 182 ? 157.797 112.207 138.349 1.00 28.89  ? 161 ASN B O   1 
ATOM   1154 C CB  . ASN A 1 182 ? 159.885 110.982 136.904 1.00 32.55  ? 161 ASN B CB  1 
ATOM   1155 C CG  . ASN A 1 182 ? 160.392 110.344 138.176 1.00 37.10  ? 161 ASN B CG  1 
ATOM   1156 O OD1 . ASN A 1 182 ? 161.588 110.353 138.454 1.00 43.65  ? 161 ASN B OD1 1 
ATOM   1157 N ND2 . ASN A 1 182 ? 159.481 109.782 138.958 1.00 40.88  ? 161 ASN B ND2 1 
ATOM   1158 N N   . SER A 1 183 ? 158.070 114.177 137.302 1.00 30.98  ? 162 SER B N   1 
ATOM   1159 C CA  . SER A 1 183 ? 156.803 114.742 137.747 1.00 25.05  ? 162 SER B CA  1 
ATOM   1160 C C   . SER A 1 183 ? 156.532 116.017 136.967 1.00 26.11  ? 162 SER B C   1 
ATOM   1161 O O   . SER A 1 183 ? 157.434 116.833 136.776 1.00 37.85  ? 162 SER B O   1 
ATOM   1162 C CB  . SER A 1 183 ? 156.818 115.039 139.250 1.00 26.16  ? 162 SER B CB  1 
ATOM   1163 O OG  . SER A 1 183 ? 156.757 113.843 140.004 1.00 37.11  ? 162 SER B OG  1 
ATOM   1164 N N   . VAL A 1 184 ? 155.288 116.182 136.528 1.00 16.69  ? 163 VAL B N   1 
ATOM   1165 C CA  . VAL A 1 184 ? 154.843 117.368 135.805 1.00 16.98  ? 163 VAL B CA  1 
ATOM   1166 C C   . VAL A 1 184 ? 153.700 117.996 136.585 1.00 7.65   ? 163 VAL B C   1 
ATOM   1167 O O   . VAL A 1 184 ? 152.723 117.317 136.907 1.00 19.97  ? 163 VAL B O   1 
ATOM   1168 C CB  . VAL A 1 184 ? 154.391 117.027 134.374 1.00 11.71  ? 163 VAL B CB  1 
ATOM   1169 C CG1 . VAL A 1 184 ? 153.901 118.271 133.671 1.00 11.87  ? 163 VAL B CG1 1 
ATOM   1170 C CG2 . VAL A 1 184 ? 155.518 116.392 133.605 1.00 16.59  ? 163 VAL B CG2 1 
ATOM   1171 N N   . ARG A 1 185 ? 153.817 119.286 136.879 1.00 11.92  ? 164 ARG B N   1 
ATOM   1172 C CA  . ARG A 1 185 ? 152.803 120.019 137.629 1.00 12.19  ? 164 ARG B CA  1 
ATOM   1173 C C   . ARG A 1 185 ? 152.301 121.167 136.768 1.00 19.58  ? 164 ARG B C   1 
ATOM   1174 O O   . ARG A 1 185 ? 153.040 122.122 136.510 1.00 33.58  ? 164 ARG B O   1 
ATOM   1175 C CB  . ARG A 1 185 ? 153.364 120.539 138.950 1.00 17.01  ? 164 ARG B CB  1 
ATOM   1176 C CG  . ARG A 1 185 ? 154.270 119.559 139.667 1.00 24.38  ? 164 ARG B CG  1 
ATOM   1177 C CD  . ARG A 1 185 ? 154.419 119.919 141.129 1.00 18.88  ? 164 ARG B CD  1 
ATOM   1178 N NE  . ARG A 1 185 ? 154.840 118.776 141.929 1.00 27.40  ? 164 ARG B NE  1 
ATOM   1179 C CZ  . ARG A 1 185 ? 154.517 118.597 143.202 1.00 34.66  ? 164 ARG B CZ  1 
ATOM   1180 N NH1 . ARG A 1 185 ? 153.767 119.470 143.854 1.00 30.11  ? 164 ARG B NH1 1 
ATOM   1181 N NH2 . ARG A 1 185 ? 154.955 117.513 143.836 1.00 27.85  ? 164 ARG B NH2 1 
ATOM   1182 N N   . LEU A 1 186 ? 151.051 121.081 136.330 1.00 16.40  ? 165 LEU B N   1 
ATOM   1183 C CA  . LEU A 1 186 ? 150.422 122.135 135.549 1.00 13.43  ? 165 LEU B CA  1 
ATOM   1184 C C   . LEU A 1 186 ? 149.279 122.738 136.351 1.00 12.01  ? 165 LEU B C   1 
ATOM   1185 O O   . LEU A 1 186 ? 148.386 122.017 136.806 1.00 17.36  ? 165 LEU B O   1 
ATOM   1186 C CB  . LEU A 1 186 ? 149.916 121.602 134.206 1.00 2.45   ? 165 LEU B CB  1 
ATOM   1187 C CG  . LEU A 1 186 ? 150.876 121.785 133.028 1.00 11.04  ? 165 LEU B CG  1 
ATOM   1188 C CD1 . LEU A 1 186 ? 150.606 120.773 131.930 1.00 22.60  ? 165 LEU B CD1 1 
ATOM   1189 C CD2 . LEU A 1 186 ? 150.791 123.193 132.481 1.00 23.18  ? 165 LEU B CD2 1 
ATOM   1190 N N   . VAL A 1 187 ? 149.315 124.053 136.527 1.00 9.12   ? 166 VAL B N   1 
ATOM   1191 C CA  . VAL A 1 187 ? 148.252 124.767 137.223 1.00 3.03   ? 166 VAL B CA  1 
ATOM   1192 C C   . VAL A 1 187 ? 147.108 125.007 136.251 1.00 4.90   ? 166 VAL B C   1 
ATOM   1193 O O   . VAL A 1 187 ? 147.324 125.422 135.108 1.00 27.67  ? 166 VAL B O   1 
ATOM   1194 C CB  . VAL A 1 187 ? 148.771 126.091 137.804 1.00 4.83   ? 166 VAL B CB  1 
ATOM   1195 C CG1 . VAL A 1 187 ? 147.630 126.899 138.395 1.00 0.00   ? 166 VAL B CG1 1 
ATOM   1196 C CG2 . VAL A 1 187 ? 149.835 125.832 138.854 1.00 22.45  ? 166 VAL B CG2 1 
ATOM   1197 N N   . ILE A 1 188 ? 145.886 124.735 136.698 1.00 0.00   ? 167 ILE B N   1 
ATOM   1198 C CA  . ILE A 1 188 ? 144.692 125.013 135.920 1.00 0.00   ? 167 ILE B CA  1 
ATOM   1199 C C   . ILE A 1 188 ? 143.773 125.882 136.766 1.00 7.75   ? 167 ILE B C   1 
ATOM   1200 O O   . ILE A 1 188 ? 143.959 126.031 137.974 1.00 24.24  ? 167 ILE B O   1 
ATOM   1201 C CB  . ILE A 1 188 ? 143.972 123.727 135.470 1.00 8.38   ? 167 ILE B CB  1 
ATOM   1202 C CG1 . ILE A 1 188 ? 143.649 122.848 136.676 1.00 6.82   ? 167 ILE B CG1 1 
ATOM   1203 C CG2 . ILE A 1 188 ? 144.825 122.966 134.475 1.00 13.07  ? 167 ILE B CG2 1 
ATOM   1204 C CD1 . ILE A 1 188 ? 142.720 121.711 136.366 1.00 8.36   ? 167 ILE B CD1 1 
ATOM   1205 N N   . ARG A 1 189 ? 142.778 126.470 136.111 1.00 8.29   ? 168 ARG B N   1 
ATOM   1206 C CA  . ARG A 1 189 ? 141.869 127.400 136.760 1.00 8.97   ? 168 ARG B CA  1 
ATOM   1207 C C   . ARG A 1 189 ? 140.432 126.957 136.553 1.00 4.49   ? 168 ARG B C   1 
ATOM   1208 O O   . ARG A 1 189 ? 140.059 126.520 135.463 1.00 19.45  ? 168 ARG B O   1 
ATOM   1209 C CB  . ARG A 1 189 ? 142.048 128.817 136.220 1.00 11.37  ? 168 ARG B CB  1 
ATOM   1210 C CG  . ARG A 1 189 ? 143.242 129.551 136.784 1.00 8.14   ? 168 ARG B CG  1 
ATOM   1211 C CD  . ARG A 1 189 ? 143.148 131.029 136.493 1.00 11.29  ? 168 ARG B CD  1 
ATOM   1212 N NE  . ARG A 1 189 ? 143.717 131.364 135.195 1.00 20.85  ? 168 ARG B NE  1 
ATOM   1213 C CZ  . ARG A 1 189 ? 144.118 132.577 134.843 1.00 17.34  ? 168 ARG B CZ  1 
ATOM   1214 N NH1 . ARG A 1 189 ? 144.021 133.604 135.671 1.00 10.32  ? 168 ARG B NH1 1 
ATOM   1215 N NH2 . ARG A 1 189 ? 144.632 132.764 133.632 1.00 15.48  ? 168 ARG B NH2 1 
ATOM   1216 N N   . LYS A 1 190 ? 139.630 127.074 137.604 1.00 6.57   ? 169 LYS B N   1 
ATOM   1217 C CA  . LYS A 1 190 ? 138.189 126.894 137.516 1.00 10.00  ? 169 LYS B CA  1 
ATOM   1218 C C   . LYS A 1 190 ? 137.539 128.269 137.587 1.00 20.70  ? 169 LYS B C   1 
ATOM   1219 O O   . LYS A 1 190 ? 137.749 129.008 138.553 1.00 28.47  ? 169 LYS B O   1 
ATOM   1220 C CB  . LYS A 1 190 ? 137.678 125.989 138.635 1.00 9.86   ? 169 LYS B CB  1 
ATOM   1221 C CG  . LYS A 1 190 ? 136.185 125.758 138.593 1.00 9.61   ? 169 LYS B CG  1 
ATOM   1222 C CD  . LYS A 1 190 ? 135.707 124.985 139.802 1.00 16.74  ? 169 LYS B CD  1 
ATOM   1223 C CE  . LYS A 1 190 ? 134.206 125.111 139.952 1.00 21.39  ? 169 LYS B CE  1 
ATOM   1224 N NZ  . LYS A 1 190 ? 133.693 124.440 141.170 1.00 27.62  ? 169 LYS B NZ  1 
ATOM   1225 N N   . VAL A 1 191 ? 136.760 128.615 136.562 1.00 18.49  ? 170 VAL B N   1 
ATOM   1226 C CA  . VAL A 1 191 ? 136.240 129.964 136.400 1.00 16.93  ? 170 VAL B CA  1 
ATOM   1227 C C   . VAL A 1 191 ? 134.739 129.909 136.162 1.00 19.11  ? 170 VAL B C   1 
ATOM   1228 O O   . VAL A 1 191 ? 134.171 128.863 135.847 1.00 32.90  ? 170 VAL B O   1 
ATOM   1229 C CB  . VAL A 1 191 ? 136.931 130.721 135.244 1.00 8.81   ? 170 VAL B CB  1 
ATOM   1230 C CG1 . VAL A 1 191 ? 138.393 130.952 135.563 1.00 16.22  ? 170 VAL B CG1 1 
ATOM   1231 C CG2 . VAL A 1 191 ? 136.781 129.959 133.944 1.00 9.02   ? 170 VAL B CG2 1 
ATOM   1232 N N   . GLN A 1 192 ? 134.101 131.064 136.333 1.00 11.95  ? 171 GLN B N   1 
ATOM   1233 C CA  . GLN A 1 192 ? 132.689 131.254 136.046 1.00 0.00   ? 171 GLN B CA  1 
ATOM   1234 C C   . GLN A 1 192 ? 132.516 132.532 135.242 1.00 14.34  ? 171 GLN B C   1 
ATOM   1235 O O   . GLN A 1 192 ? 133.406 133.383 135.193 1.00 20.86  ? 171 GLN B O   1 
ATOM   1236 C CB  . GLN A 1 192 ? 131.852 131.337 137.324 1.00 9.23   ? 171 GLN B CB  1 
ATOM   1237 C CG  . GLN A 1 192 ? 131.421 130.009 137.884 1.00 13.46  ? 171 GLN B CG  1 
ATOM   1238 C CD  . GLN A 1 192 ? 131.021 130.105 139.338 1.00 17.53  ? 171 GLN B CD  1 
ATOM   1239 O OE1 . GLN A 1 192 ? 131.639 130.829 140.116 1.00 26.00  ? 171 GLN B OE1 1 
ATOM   1240 N NE2 . GLN A 1 192 ? 129.981 129.374 139.713 1.00 24.35  ? 171 GLN B NE2 1 
ATOM   1241 N N   . TYR A 1 193 ? 131.351 132.663 134.616 1.00 18.32  ? 172 TYR B N   1 
ATOM   1242 C CA  . TYR A 1 193 ? 131.032 133.823 133.802 1.00 12.63  ? 172 TYR B CA  1 
ATOM   1243 C C   . TYR A 1 193 ? 129.633 134.317 134.137 1.00 18.81  ? 172 TYR B C   1 
ATOM   1244 O O   . TYR A 1 193 ? 128.833 133.611 134.754 1.00 23.31  ? 172 TYR B O   1 
ATOM   1245 C CB  . TYR A 1 193 ? 131.152 133.502 132.311 1.00 6.09   ? 172 TYR B CB  1 
ATOM   1246 C CG  . TYR A 1 193 ? 132.568 133.186 131.903 1.00 17.45  ? 172 TYR B CG  1 
ATOM   1247 C CD1 . TYR A 1 193 ? 133.584 134.109 132.096 1.00 17.17  ? 172 TYR B CD1 1 
ATOM   1248 C CD2 . TYR A 1 193 ? 132.896 131.962 131.345 1.00 14.01  ? 172 TYR B CD2 1 
ATOM   1249 C CE1 . TYR A 1 193 ? 134.878 133.826 131.736 1.00 12.24  ? 172 TYR B CE1 1 
ATOM   1250 C CE2 . TYR A 1 193 ? 134.190 131.673 130.982 1.00 9.14   ? 172 TYR B CE2 1 
ATOM   1251 C CZ  . TYR A 1 193 ? 135.175 132.608 131.179 1.00 16.54  ? 172 TYR B CZ  1 
ATOM   1252 O OH  . TYR A 1 193 ? 136.467 132.323 130.816 1.00 34.40  ? 172 TYR B OH  1 
ATOM   1253 N N   . ALA A 1 194 ? 129.355 135.549 133.732 1.00 11.78  ? 173 ALA B N   1 
ATOM   1254 C CA  . ALA A 1 194 ? 128.097 136.187 134.086 1.00 7.44   ? 173 ALA B CA  1 
ATOM   1255 C C   . ALA A 1 194 ? 126.928 135.432 133.465 1.00 19.35  ? 173 ALA B C   1 
ATOM   1256 O O   . ALA A 1 194 ? 126.976 135.097 132.274 1.00 31.32  ? 173 ALA B O   1 
ATOM   1257 C CB  . ALA A 1 194 ? 128.088 137.640 133.620 1.00 15.05  ? 173 ALA B CB  1 
ATOM   1258 N N   . PRO A 1 195 ? 125.877 135.136 134.226 1.00 22.14  ? 174 PRO B N   1 
ATOM   1259 C CA  . PRO A 1 195 ? 124.710 134.468 133.643 1.00 27.39  ? 174 PRO B CA  1 
ATOM   1260 C C   . PRO A 1 195 ? 124.029 135.341 132.600 1.00 33.02  ? 174 PRO B C   1 
ATOM   1261 O O   . PRO A 1 195 ? 123.988 136.568 132.713 1.00 39.51  ? 174 PRO B O   1 
ATOM   1262 C CB  . PRO A 1 195 ? 123.800 134.220 134.850 1.00 27.14  ? 174 PRO B CB  1 
ATOM   1263 C CG  . PRO A 1 195 ? 124.273 135.162 135.894 1.00 27.68  ? 174 PRO B CG  1 
ATOM   1264 C CD  . PRO A 1 195 ? 125.733 135.344 135.675 1.00 16.70  ? 174 PRO B CD  1 
ATOM   1265 N N   . GLU A 1 196 ? 123.482 134.687 131.573 1.00 33.51  ? 175 GLU B N   1 
ATOM   1266 C CA  . GLU A 1 196 ? 122.870 135.400 130.459 1.00 34.33  ? 175 GLU B CA  1 
ATOM   1267 C C   . GLU A 1 196 ? 121.526 136.020 130.813 1.00 43.53  ? 175 GLU B C   1 
ATOM   1268 O O   . GLU A 1 196 ? 121.011 136.823 130.028 1.00 43.44  ? 175 GLU B O   1 
ATOM   1269 C CB  . GLU A 1 196 ? 122.705 134.461 129.264 1.00 35.60  ? 175 GLU B CB  1 
ATOM   1270 N N   . ARG A 1 197 ? 120.945 135.668 131.956 1.00 43.39  ? 176 ARG B N   1 
ATOM   1271 C CA  . ARG A 1 197 ? 119.663 136.224 132.373 1.00 40.98  ? 176 ARG B CA  1 
ATOM   1272 C C   . ARG A 1 197 ? 119.888 137.237 133.485 1.00 43.26  ? 176 ARG B C   1 
ATOM   1273 O O   . ARG A 1 197 ? 120.322 136.854 134.583 1.00 42.17  ? 176 ARG B O   1 
ATOM   1274 C CB  . ARG A 1 197 ? 118.720 135.116 132.843 1.00 42.10  ? 176 ARG B CB  1 
ATOM   1275 N N   . PRO A 1 198 ? 119.624 138.522 133.256 1.00 48.99  ? 177 PRO B N   1 
ATOM   1276 C CA  . PRO A 1 198 ? 119.842 139.518 134.310 1.00 38.50  ? 177 PRO B CA  1 
ATOM   1277 C C   . PRO A 1 198 ? 118.894 139.320 135.480 1.00 40.96  ? 177 PRO B C   1 
ATOM   1278 O O   . PRO A 1 198 ? 117.747 138.896 135.320 1.00 51.30  ? 177 PRO B O   1 
ATOM   1279 C CB  . PRO A 1 198 ? 119.572 140.849 133.600 1.00 42.44  ? 177 PRO B CB  1 
ATOM   1280 C CG  . PRO A 1 198 ? 118.649 140.493 132.484 1.00 38.64  ? 177 PRO B CG  1 
ATOM   1281 C CD  . PRO A 1 198 ? 119.064 139.121 132.033 1.00 43.14  ? 177 PRO B CD  1 
ATOM   1282 N N   . GLY A 1 199 ? 119.389 139.640 136.672 1.00 39.83  ? 178 GLY B N   1 
ATOM   1283 C CA  . GLY A 1 199 ? 118.595 139.548 137.873 1.00 38.22  ? 178 GLY B CA  1 
ATOM   1284 C C   . GLY A 1 199 ? 117.768 140.796 138.104 1.00 43.70  ? 178 GLY B C   1 
ATOM   1285 O O   . GLY A 1 199 ? 117.875 141.784 137.371 1.00 46.23  ? 178 GLY B O   1 
ATOM   1286 N N   . PRO A 1 200 ? 116.918 140.773 139.130 1.00 48.81  ? 179 PRO B N   1 
ATOM   1287 C CA  . PRO A 1 200 ? 116.123 141.963 139.451 1.00 46.18  ? 179 PRO B CA  1 
ATOM   1288 C C   . PRO A 1 200 ? 117.007 143.111 139.915 1.00 47.73  ? 179 PRO B C   1 
ATOM   1289 O O   . PRO A 1 200 ? 118.046 142.911 140.547 1.00 50.09  ? 179 PRO B O   1 
ATOM   1290 C CB  . PRO A 1 200 ? 115.196 141.479 140.571 1.00 50.69  ? 179 PRO B CB  1 
ATOM   1291 C CG  . PRO A 1 200 ? 115.919 140.329 141.185 1.00 49.53  ? 179 PRO B CG  1 
ATOM   1292 C CD  . PRO A 1 200 ? 116.668 139.666 140.068 1.00 46.71  ? 179 PRO B CD  1 
ATOM   1293 N N   . GLN A 1 201 ? 116.575 144.323 139.597 1.00 38.86  ? 180 GLN B N   1 
ATOM   1294 C CA  . GLN A 1 201 ? 117.355 145.511 139.925 1.00 35.79  ? 180 GLN B CA  1 
ATOM   1295 C C   . GLN A 1 201 ? 117.398 145.713 141.436 1.00 36.85  ? 180 GLN B C   1 
ATOM   1296 O O   . GLN A 1 201 ? 116.348 145.686 142.088 1.00 43.47  ? 180 GLN B O   1 
ATOM   1297 C CB  . GLN A 1 201 ? 116.752 146.729 139.230 1.00 34.48  ? 180 GLN B CB  1 
ATOM   1298 C CG  . GLN A 1 201 ? 117.084 148.060 139.870 1.00 36.91  ? 180 GLN B CG  1 
ATOM   1299 C CD  . GLN A 1 201 ? 115.902 149.013 139.877 1.00 42.68  ? 180 GLN B CD  1 
ATOM   1300 O OE1 . GLN A 1 201 ? 114.749 148.589 139.942 1.00 46.27  ? 180 GLN B OE1 1 
ATOM   1301 N NE2 . GLN A 1 201 ? 116.186 150.307 139.809 1.00 38.95  ? 180 GLN B NE2 1 
ATOM   1302 N N   . PRO A 1 202 ? 118.578 145.903 142.028 1.00 28.21  ? 181 PRO B N   1 
ATOM   1303 C CA  . PRO A 1 202 ? 118.658 146.053 143.486 1.00 27.90  ? 181 PRO B CA  1 
ATOM   1304 C C   . PRO A 1 202 ? 117.923 147.292 143.973 1.00 22.22  ? 181 PRO B C   1 
ATOM   1305 O O   . PRO A 1 202 ? 117.835 148.305 143.279 1.00 31.22  ? 181 PRO B O   1 
ATOM   1306 C CB  . PRO A 1 202 ? 120.165 146.156 143.752 1.00 20.46  ? 181 PRO B CB  1 
ATOM   1307 C CG  . PRO A 1 202 ? 120.816 145.595 142.541 1.00 17.65  ? 181 PRO B CG  1 
ATOM   1308 C CD  . PRO A 1 202 ? 119.908 145.915 141.400 1.00 25.59  ? 181 PRO B CD  1 
ATOM   1309 N N   . THR A 1 203 ? 117.383 147.191 145.186 1.00 25.96  ? 182 THR B N   1 
ATOM   1310 C CA  . THR A 1 203 ? 116.618 148.272 145.795 1.00 30.01  ? 182 THR B CA  1 
ATOM   1311 C C   . THR A 1 203 ? 116.521 148.005 147.288 1.00 36.74  ? 182 THR B C   1 
ATOM   1312 O O   . THR A 1 203 ? 116.151 146.899 147.694 1.00 43.46  ? 182 THR B O   1 
ATOM   1313 C CB  . THR A 1 203 ? 115.215 148.376 145.184 1.00 33.72  ? 182 THR B CB  1 
ATOM   1314 O OG1 . THR A 1 203 ? 115.315 148.754 143.806 1.00 36.12  ? 182 THR B OG1 1 
ATOM   1315 C CG2 . THR A 1 203 ? 114.383 149.408 145.925 1.00 33.99  ? 182 THR B CG2 1 
ATOM   1316 N N   . ALA A 1 204 ? 116.853 149.007 148.100 1.00 22.22  ? 183 ALA B N   1 
ATOM   1317 C CA  . ALA A 1 204 ? 116.758 148.887 149.547 1.00 26.96  ? 183 ALA B CA  1 
ATOM   1318 C C   . ALA A 1 204 ? 116.157 150.162 150.119 1.00 30.44  ? 183 ALA B C   1 
ATOM   1319 O O   . ALA A 1 204 ? 116.067 151.190 149.445 1.00 43.30  ? 183 ALA B O   1 
ATOM   1320 C CB  . ALA A 1 204 ? 118.120 148.594 150.178 1.00 25.14  ? 183 ALA B CB  1 
ATOM   1321 N N   . GLU A 1 205 ? 115.735 150.086 151.380 1.00 39.81  ? 184 GLU B N   1 
ATOM   1322 C CA  . GLU A 1 205 ? 115.079 151.205 152.039 1.00 34.54  ? 184 GLU B CA  1 
ATOM   1323 C C   . GLU A 1 205 ? 115.428 151.207 153.519 1.00 40.20  ? 184 GLU B C   1 
ATOM   1324 O O   . GLU A 1 205 ? 115.864 150.198 154.078 1.00 52.27  ? 184 GLU B O   1 
ATOM   1325 C CB  . GLU A 1 205 ? 113.558 151.152 151.871 1.00 37.59  ? 184 GLU B CB  1 
ATOM   1326 C CG  . GLU A 1 205 ? 113.061 151.665 150.541 1.00 41.10  ? 184 GLU B CG  1 
ATOM   1327 C CD  . GLU A 1 205 ? 111.554 151.656 150.448 1.00 49.28  ? 184 GLU B CD  1 
ATOM   1328 O OE1 . GLU A 1 205 ? 110.903 151.207 151.413 1.00 47.07  ? 184 GLU B OE1 1 
ATOM   1329 O OE2 . GLU A 1 205 ? 111.020 152.097 149.410 1.00 50.94  ? 184 GLU B OE2 1 
ATOM   1330 N N   . THR A 1 206 ? 115.226 152.361 154.148 1.00 29.54  ? 185 THR B N   1 
ATOM   1331 C CA  . THR A 1 206 ? 115.388 152.512 155.587 1.00 32.18  ? 185 THR B CA  1 
ATOM   1332 C C   . THR A 1 206 ? 114.459 153.619 156.057 1.00 36.32  ? 185 THR B C   1 
ATOM   1333 O O   . THR A 1 206 ? 114.241 154.598 155.342 1.00 45.68  ? 185 THR B O   1 
ATOM   1334 C CB  . THR A 1 206 ? 116.836 152.836 155.972 1.00 30.91  ? 185 THR B CB  1 
ATOM   1335 O OG1 . THR A 1 206 ? 117.715 151.878 155.379 1.00 32.67  ? 185 THR B OG1 1 
ATOM   1336 C CG2 . THR A 1 206 ? 117.016 152.793 157.478 1.00 35.33  ? 185 THR B CG2 1 
ATOM   1337 N N   . THR A 1 207 ? 113.901 153.447 157.254 1.00 43.25  ? 186 THR B N   1 
ATOM   1338 C CA  . THR A 1 207 ? 113.028 154.446 157.875 1.00 43.43  ? 186 THR B CA  1 
ATOM   1339 C C   . THR A 1 207 ? 113.395 154.488 159.356 1.00 48.68  ? 186 THR B C   1 
ATOM   1340 O O   . THR A 1 207 ? 112.889 153.695 160.154 1.00 50.63  ? 186 THR B O   1 
ATOM   1341 C CB  . THR A 1 207 ? 111.558 154.114 157.664 1.00 45.55  ? 186 THR B CB  1 
ATOM   1342 O OG1 . THR A 1 207 ? 111.328 153.820 156.281 1.00 38.99  ? 186 THR B OG1 1 
ATOM   1343 C CG2 . THR A 1 207 ? 110.689 155.286 158.073 1.00 46.26  ? 186 THR B CG2 1 
ATOM   1344 N N   . ARG A 1 208 ? 114.280 155.412 159.716 1.00 52.27  ? 187 ARG B N   1 
ATOM   1345 C CA  . ARG A 1 208 ? 114.792 155.518 161.076 1.00 53.39  ? 187 ARG B CA  1 
ATOM   1346 C C   . ARG A 1 208 ? 114.046 156.621 161.814 1.00 54.42  ? 187 ARG B C   1 
ATOM   1347 O O   . ARG A 1 208 ? 114.114 157.790 161.422 1.00 57.14  ? 187 ARG B O   1 
ATOM   1348 C CB  . ARG A 1 208 ? 116.294 155.796 161.072 1.00 51.86  ? 187 ARG B CB  1 
ATOM   1349 C CG  . ARG A 1 208 ? 116.916 155.816 162.454 1.00 54.53  ? 187 ARG B CG  1 
ATOM   1350 C CD  . ARG A 1 208 ? 118.214 155.027 162.491 1.00 54.86  ? 187 ARG B CD  1 
ATOM   1351 N NE  . ARG A 1 208 ? 118.615 154.703 163.854 1.00 58.72  ? 187 ARG B NE  1 
ATOM   1352 C CZ  . ARG A 1 208 ? 119.168 155.562 164.700 1.00 58.33  ? 187 ARG B CZ  1 
ATOM   1353 N NH1 . ARG A 1 208 ? 119.418 156.813 164.352 1.00 56.14  ? 187 ARG B NH1 1 
ATOM   1354 N NH2 . ARG A 1 208 ? 119.482 155.153 165.926 1.00 52.74  ? 187 ARG B NH2 1 
ATOM   1355 N N   . GLN A 1 209 ? 113.343 156.248 162.880 1.00 63.11  ? 188 GLN B N   1 
ATOM   1356 C CA  . GLN A 1 209 ? 112.612 157.200 163.710 1.00 65.08  ? 188 GLN B CA  1 
ATOM   1357 C C   . GLN A 1 209 ? 113.536 157.685 164.821 1.00 69.20  ? 188 GLN B C   1 
ATOM   1358 O O   . GLN A 1 209 ? 113.817 156.948 165.771 1.00 67.85  ? 188 GLN B O   1 
ATOM   1359 C CB  . GLN A 1 209 ? 111.350 156.560 164.280 1.00 62.99  ? 188 GLN B CB  1 
ATOM   1360 N N   . PHE A 1 210 ? 114.008 158.922 164.701 1.00 77.21  ? 189 PHE B N   1 
ATOM   1361 C CA  . PHE A 1 210 ? 114.951 159.459 165.668 1.00 75.35  ? 189 PHE B CA  1 
ATOM   1362 C C   . PHE A 1 210 ? 114.260 159.730 167.002 1.00 76.99  ? 189 PHE B C   1 
ATOM   1363 O O   . PHE A 1 210 ? 113.042 159.915 167.080 1.00 76.45  ? 189 PHE B O   1 
ATOM   1364 C CB  . PHE A 1 210 ? 115.598 160.735 165.131 1.00 71.86  ? 189 PHE B CB  1 
ATOM   1365 C CG  . PHE A 1 210 ? 116.873 160.490 164.381 1.00 72.22  ? 189 PHE B CG  1 
ATOM   1366 C CD1 . PHE A 1 210 ? 116.845 160.053 163.069 1.00 72.43  ? 189 PHE B CD1 1 
ATOM   1367 C CD2 . PHE A 1 210 ? 118.099 160.679 164.991 1.00 75.02  ? 189 PHE B CD2 1 
ATOM   1368 C CE1 . PHE A 1 210 ? 118.015 159.819 162.377 1.00 73.00  ? 189 PHE B CE1 1 
ATOM   1369 C CE2 . PHE A 1 210 ? 119.272 160.447 164.303 1.00 75.86  ? 189 PHE B CE2 1 
ATOM   1370 C CZ  . PHE A 1 210 ? 119.230 160.016 162.994 1.00 71.34  ? 189 PHE B CZ  1 
ATOM   1371 N N   . LEU A 1 211 ? 115.063 159.743 168.065 1.00 90.55  ? 190 LEU B N   1 
ATOM   1372 C CA  . LEU A 1 211 ? 114.528 159.896 169.412 1.00 91.57  ? 190 LEU B CA  1 
ATOM   1373 C C   . LEU A 1 211 ? 113.849 161.250 169.576 1.00 93.47  ? 190 LEU B C   1 
ATOM   1374 O O   . LEU A 1 211 ? 114.407 162.288 169.208 1.00 92.72  ? 190 LEU B O   1 
ATOM   1375 C CB  . LEU A 1 211 ? 115.647 159.737 170.441 1.00 89.94  ? 190 LEU B CB  1 
ATOM   1376 N N   . MET A 1 212 ? 112.640 161.229 170.144 1.00 96.05  ? 191 MET B N   1 
ATOM   1377 C CA  . MET A 1 212 ? 111.846 162.436 170.377 1.00 96.72  ? 191 MET B CA  1 
ATOM   1378 C C   . MET A 1 212 ? 111.646 163.233 169.090 1.00 97.08  ? 191 MET B C   1 
ATOM   1379 O O   . MET A 1 212 ? 111.771 164.459 169.070 1.00 95.34  ? 191 MET B O   1 
ATOM   1380 C CB  . MET A 1 212 ? 112.477 163.310 171.465 1.00 95.59  ? 191 MET B CB  1 
ATOM   1381 N N   . SER A 1 213 ? 111.335 162.530 168.001 1.00 92.80  ? 192 SER B N   1 
ATOM   1382 C CA  . SER A 1 213 ? 111.123 163.188 166.713 1.00 91.15  ? 192 SER B CA  1 
ATOM   1383 C C   . SER A 1 213 ? 110.266 162.282 165.840 1.00 92.08  ? 192 SER B C   1 
ATOM   1384 O O   . SER A 1 213 ? 110.717 161.204 165.441 1.00 93.07  ? 192 SER B O   1 
ATOM   1385 C CB  . SER A 1 213 ? 112.454 163.500 166.040 1.00 89.95  ? 192 SER B CB  1 
ATOM   1386 N N   . ASP A 1 214 ? 109.043 162.718 165.547 1.00 79.75  ? 193 ASP B N   1 
ATOM   1387 C CA  . ASP A 1 214 ? 108.182 162.011 164.614 1.00 78.30  ? 193 ASP B CA  1 
ATOM   1388 C C   . ASP A 1 214 ? 108.562 162.379 163.181 1.00 78.49  ? 193 ASP B C   1 
ATOM   1389 O O   . ASP A 1 214 ? 109.511 163.131 162.939 1.00 78.64  ? 193 ASP B O   1 
ATOM   1390 C CB  . ASP A 1 214 ? 106.716 162.328 164.898 1.00 77.14  ? 193 ASP B CB  1 
ATOM   1391 N N   . LYS A 1 215 ? 107.806 161.843 162.215 1.00 69.91  ? 194 LYS B N   1 
ATOM   1392 C CA  . LYS A 1 215 ? 108.049 162.083 160.796 1.00 69.04  ? 194 LYS B CA  1 
ATOM   1393 C C   . LYS A 1 215 ? 109.473 161.667 160.449 1.00 69.37  ? 194 LYS B C   1 
ATOM   1394 O O   . LYS A 1 215 ? 110.333 162.525 160.216 1.00 69.72  ? 194 LYS B O   1 
ATOM   1395 C CB  . LYS A 1 215 ? 107.808 163.552 160.436 1.00 65.83  ? 194 LYS B CB  1 
ATOM   1396 N N   . PRO A 1 216 ? 109.759 160.372 160.400 1.00 58.63  ? 195 PRO B N   1 
ATOM   1397 C CA  . PRO A 1 216 ? 111.147 159.913 160.401 1.00 56.41  ? 195 PRO B CA  1 
ATOM   1398 C C   . PRO A 1 216 ? 111.822 160.055 159.042 1.00 54.24  ? 195 PRO B C   1 
ATOM   1399 O O   . PRO A 1 216 ? 111.193 160.289 158.010 1.00 54.91  ? 195 PRO B O   1 
ATOM   1400 C CB  . PRO A 1 216 ? 111.000 158.447 160.804 1.00 54.86  ? 195 PRO B CB  1 
ATOM   1401 C CG  . PRO A 1 216 ? 109.639 158.038 160.240 1.00 57.97  ? 195 PRO B CG  1 
ATOM   1402 C CD  . PRO A 1 216 ? 108.869 159.310 159.905 1.00 57.51  ? 195 PRO B CD  1 
ATOM   1403 N N   . LEU A 1 217 ? 113.143 159.912 159.073 1.00 41.95  ? 196 LEU B N   1 
ATOM   1404 C CA  . LEU A 1 217 ? 113.965 159.978 157.877 1.00 34.53  ? 196 LEU B CA  1 
ATOM   1405 C C   . LEU A 1 217 ? 113.774 158.719 157.040 1.00 43.13  ? 196 LEU B C   1 
ATOM   1406 O O   . LEU A 1 217 ? 113.485 157.640 157.561 1.00 53.19  ? 196 LEU B O   1 
ATOM   1407 C CB  . LEU A 1 217 ? 115.434 160.159 158.269 1.00 32.00  ? 196 LEU B CB  1 
ATOM   1408 C CG  . LEU A 1 217 ? 116.586 159.954 157.287 1.00 34.86  ? 196 LEU B CG  1 
ATOM   1409 C CD1 . LEU A 1 217 ? 117.739 160.844 157.694 1.00 41.21  ? 196 LEU B CD1 1 
ATOM   1410 C CD2 . LEU A 1 217 ? 117.043 158.507 157.260 1.00 40.28  ? 196 LEU B CD2 1 
ATOM   1411 N N   . HIS A 1 218 ? 113.929 158.869 155.727 1.00 37.54  ? 197 HIS B N   1 
ATOM   1412 C CA  . HIS A 1 218 ? 113.749 157.775 154.785 1.00 28.90  ? 197 HIS B CA  1 
ATOM   1413 C C   . HIS A 1 218 ? 114.914 157.750 153.807 1.00 30.71  ? 197 HIS B C   1 
ATOM   1414 O O   . HIS A 1 218 ? 115.445 158.799 153.436 1.00 45.08  ? 197 HIS B O   1 
ATOM   1415 C CB  . HIS A 1 218 ? 112.427 157.921 154.029 1.00 32.60  ? 197 HIS B CB  1 
ATOM   1416 C CG  . HIS A 1 218 ? 111.816 156.622 153.608 1.00 38.92  ? 197 HIS B CG  1 
ATOM   1417 N ND1 . HIS A 1 218 ? 112.550 155.465 153.461 1.00 48.21  ? 197 HIS B ND1 1 
ATOM   1418 C CD2 . HIS A 1 218 ? 110.540 156.300 153.294 1.00 41.46  ? 197 HIS B CD2 1 
ATOM   1419 C CE1 . HIS A 1 218 ? 111.751 154.485 153.078 1.00 47.39  ? 197 HIS B CE1 1 
ATOM   1420 N NE2 . HIS A 1 218 ? 110.526 154.966 152.970 1.00 46.18  ? 197 HIS B NE2 1 
ATOM   1421 N N   . LEU A 1 219 ? 115.311 156.548 153.398 1.00 20.07  ? 198 LEU B N   1 
ATOM   1422 C CA  . LEU A 1 219 ? 116.382 156.350 152.430 1.00 17.76  ? 198 LEU B CA  1 
ATOM   1423 C C   . LEU A 1 219 ? 115.918 155.339 151.394 1.00 32.74  ? 198 LEU B C   1 
ATOM   1424 O O   . LEU A 1 219 ? 115.328 154.316 151.750 1.00 47.82  ? 198 LEU B O   1 
ATOM   1425 C CB  . LEU A 1 219 ? 117.661 155.868 153.117 1.00 13.69  ? 198 LEU B CB  1 
ATOM   1426 C CG  . LEU A 1 219 ? 118.893 155.732 152.232 1.00 20.04  ? 198 LEU B CG  1 
ATOM   1427 C CD1 . LEU A 1 219 ? 119.052 156.956 151.371 1.00 22.39  ? 198 LEU B CD1 1 
ATOM   1428 C CD2 . LEU A 1 219 ? 120.130 155.516 153.073 1.00 25.43  ? 198 LEU B CD2 1 
ATOM   1429 N N   . GLU A 1 220 ? 116.170 155.624 150.118 1.00 26.59  ? 199 GLU B N   1 
ATOM   1430 C CA  . GLU A 1 220 ? 115.685 154.784 149.024 1.00 18.87  ? 199 GLU B CA  1 
ATOM   1431 C C   . GLU A 1 220 ? 116.772 154.577 147.973 1.00 16.87  ? 199 GLU B C   1 
ATOM   1432 O O   . GLU A 1 220 ? 116.556 154.771 146.777 1.00 31.34  ? 199 GLU B O   1 
ATOM   1433 C CB  . GLU A 1 220 ? 114.430 155.380 148.390 1.00 26.72  ? 199 GLU B CB  1 
ATOM   1434 C CG  . GLU A 1 220 ? 113.131 154.882 148.996 1.00 30.47  ? 199 GLU B CG  1 
ATOM   1435 C CD  . GLU A 1 220 ? 111.972 155.833 148.761 1.00 40.51  ? 199 GLU B CD  1 
ATOM   1436 O OE1 . GLU A 1 220 ? 110.823 155.470 149.092 1.00 41.99  ? 199 GLU B OE1 1 
ATOM   1437 O OE2 . GLU A 1 220 ? 112.208 156.944 148.246 1.00 37.01  ? 199 GLU B OE2 1 
ATOM   1438 N N   . ALA A 1 221 ? 117.964 154.185 148.412 1.00 9.99   ? 200 ALA B N   1 
ATOM   1439 C CA  . ALA A 1 221 ? 119.039 153.889 147.475 1.00 13.11  ? 200 ALA B CA  1 
ATOM   1440 C C   . ALA A 1 221 ? 118.718 152.642 146.660 1.00 18.30  ? 200 ALA B C   1 
ATOM   1441 O O   . ALA A 1 221 ? 118.139 151.681 147.170 1.00 37.25  ? 200 ALA B O   1 
ATOM   1442 C CB  . ALA A 1 221 ? 120.353 153.697 148.223 1.00 12.34  ? 200 ALA B CB  1 
ATOM   1443 N N   . SER A 1 222 ? 119.103 152.657 145.384 1.00 16.13  ? 201 SER B N   1 
ATOM   1444 C CA  . SER A 1 222 ? 118.831 151.532 144.497 1.00 19.66  ? 201 SER B CA  1 
ATOM   1445 C C   . SER A 1 222 ? 119.743 151.607 143.283 1.00 13.60  ? 201 SER B C   1 
ATOM   1446 O O   . SER A 1 222 ? 119.886 152.675 142.684 1.00 29.39  ? 201 SER B O   1 
ATOM   1447 C CB  . SER A 1 222 ? 117.365 151.525 144.056 1.00 24.29  ? 201 SER B CB  1 
ATOM   1448 O OG  . SER A 1 222 ? 117.080 152.635 143.227 1.00 31.45  ? 201 SER B OG  1 
ATOM   1449 N N   . LEU A 1 223 ? 120.335 150.475 142.911 1.00 5.93   ? 202 LEU B N   1 
ATOM   1450 C CA  . LEU A 1 223 ? 121.198 150.402 141.740 1.00 10.72  ? 202 LEU B CA  1 
ATOM   1451 C C   . LEU A 1 223 ? 120.345 150.306 140.476 1.00 26.88  ? 202 LEU B C   1 
ATOM   1452 O O   . LEU A 1 223 ? 119.116 150.401 140.515 1.00 36.94  ? 202 LEU B O   1 
ATOM   1453 C CB  . LEU A 1 223 ? 122.155 149.222 141.856 1.00 10.77  ? 202 LEU B CB  1 
ATOM   1454 C CG  . LEU A 1 223 ? 123.047 149.153 143.087 1.00 18.88  ? 202 LEU B CG  1 
ATOM   1455 C CD1 . LEU A 1 223 ? 123.731 147.804 143.158 1.00 14.74  ? 202 LEU B CD1 1 
ATOM   1456 C CD2 . LEU A 1 223 ? 124.065 150.261 143.041 1.00 20.86  ? 202 LEU B CD2 1 
ATOM   1457 N N   . ASP A 1 224 ? 120.996 150.113 139.327 1.00 17.29  ? 203 ASP B N   1 
ATOM   1458 C CA  . ASP A 1 224 ? 120.300 149.986 138.055 1.00 10.70  ? 203 ASP B CA  1 
ATOM   1459 C C   . ASP A 1 224 ? 120.447 148.618 137.410 1.00 25.54  ? 203 ASP B C   1 
ATOM   1460 O O   . ASP A 1 224 ? 119.601 148.247 136.592 1.00 30.95  ? 203 ASP B O   1 
ATOM   1461 C CB  . ASP A 1 224 ? 120.794 151.049 137.064 1.00 20.61  ? 203 ASP B CB  1 
ATOM   1462 C CG  . ASP A 1 224 ? 122.304 151.083 136.951 1.00 27.59  ? 203 ASP B CG  1 
ATOM   1463 O OD1 . ASP A 1 224 ? 122.981 150.717 137.932 1.00 27.37  ? 203 ASP B OD1 1 
ATOM   1464 O OD2 . ASP A 1 224 ? 122.814 151.475 135.881 1.00 20.83  ? 203 ASP B OD2 1 
ATOM   1465 N N   . LYS A 1 225 ? 121.493 147.871 137.747 1.00 26.19  ? 204 LYS B N   1 
ATOM   1466 C CA  . LYS A 1 225 ? 121.730 146.544 137.205 1.00 14.75  ? 204 LYS B CA  1 
ATOM   1467 C C   . LYS A 1 225 ? 121.943 145.566 138.347 1.00 14.21  ? 204 LYS B C   1 
ATOM   1468 O O   . LYS A 1 225 ? 122.433 145.935 139.416 1.00 20.86  ? 204 LYS B O   1 
ATOM   1469 C CB  . LYS A 1 225 ? 122.959 146.511 136.291 1.00 9.95   ? 204 LYS B CB  1 
ATOM   1470 C CG  . LYS A 1 225 ? 122.783 147.186 134.954 1.00 13.17  ? 204 LYS B CG  1 
ATOM   1471 C CD  . LYS A 1 225 ? 124.014 146.975 134.097 1.00 7.29   ? 204 LYS B CD  1 
ATOM   1472 C CE  . LYS A 1 225 ? 124.419 148.251 133.390 1.00 15.73  ? 204 LYS B CE  1 
ATOM   1473 N NZ  . LYS A 1 225 ? 125.892 148.348 133.224 1.00 26.44  ? 204 LYS B NZ  1 
ATOM   1474 N N   . GLU A 1 226 ? 121.572 144.309 138.113 1.00 18.44  ? 205 GLU B N   1 
ATOM   1475 C CA  . GLU A 1 226 ? 121.937 143.263 139.059 1.00 13.64  ? 205 GLU B CA  1 
ATOM   1476 C C   . GLU A 1 226 ? 123.354 142.766 138.810 1.00 21.03  ? 205 GLU B C   1 
ATOM   1477 O O   . GLU A 1 226 ? 124.087 142.475 139.760 1.00 15.69  ? 205 GLU B O   1 
ATOM   1478 C CB  . GLU A 1 226 ? 120.946 142.105 138.975 1.00 22.60  ? 205 GLU B CB  1 
ATOM   1479 C CG  . GLU A 1 226 ? 120.802 141.325 140.268 1.00 27.52  ? 205 GLU B CG  1 
ATOM   1480 C CD  . GLU A 1 226 ? 121.841 140.234 140.418 1.00 27.34  ? 205 GLU B CD  1 
ATOM   1481 O OE1 . GLU A 1 226 ? 121.698 139.179 139.765 1.00 27.79  ? 205 GLU B OE1 1 
ATOM   1482 O OE2 . GLU A 1 226 ? 122.798 140.430 141.194 1.00 20.79  ? 205 GLU B OE2 1 
ATOM   1483 N N   . ILE A 1 227 ? 123.758 142.678 137.546 1.00 11.87  ? 206 ILE B N   1 
ATOM   1484 C CA  . ILE A 1 227 ? 125.048 142.124 137.155 1.00 4.17   ? 206 ILE B CA  1 
ATOM   1485 C C   . ILE A 1 227 ? 125.875 143.224 136.512 1.00 7.53   ? 206 ILE B C   1 
ATOM   1486 O O   . ILE A 1 227 ? 125.400 143.914 135.603 1.00 22.33  ? 206 ILE B O   1 
ATOM   1487 C CB  . ILE A 1 227 ? 124.888 140.935 136.190 1.00 10.57  ? 206 ILE B CB  1 
ATOM   1488 C CG1 . ILE A 1 227 ? 124.028 139.846 136.826 1.00 14.34  ? 206 ILE B CG1 1 
ATOM   1489 C CG2 . ILE A 1 227 ? 126.247 140.382 135.797 1.00 11.66  ? 206 ILE B CG2 1 
ATOM   1490 C CD1 . ILE A 1 227 ? 123.615 138.769 135.873 1.00 20.15  ? 206 ILE B CD1 1 
ATOM   1491 N N   . TYR A 1 228 ? 127.108 143.380 136.981 1.00 12.15  ? 207 TYR B N   1 
ATOM   1492 C CA  . TYR A 1 228 ? 128.058 144.326 136.426 1.00 4.07   ? 207 TYR B CA  1 
ATOM   1493 C C   . TYR A 1 228 ? 129.297 143.578 135.960 1.00 8.63   ? 207 TYR B C   1 
ATOM   1494 O O   . TYR A 1 228 ? 129.600 142.482 136.434 1.00 22.03  ? 207 TYR B O   1 
ATOM   1495 C CB  . TYR A 1 228 ? 128.451 145.396 137.453 1.00 2.18   ? 207 TYR B CB  1 
ATOM   1496 C CG  . TYR A 1 228 ? 127.373 146.417 137.720 1.00 0.00   ? 207 TYR B CG  1 
ATOM   1497 C CD1 . TYR A 1 228 ? 127.268 147.558 136.947 1.00 1.62   ? 207 TYR B CD1 1 
ATOM   1498 C CD2 . TYR A 1 228 ? 126.462 146.237 138.746 1.00 1.61   ? 207 TYR B CD2 1 
ATOM   1499 C CE1 . TYR A 1 228 ? 126.285 148.486 137.184 1.00 5.97   ? 207 TYR B CE1 1 
ATOM   1500 C CE2 . TYR A 1 228 ? 125.477 147.160 138.990 1.00 0.00   ? 207 TYR B CE2 1 
ATOM   1501 C CZ  . TYR A 1 228 ? 125.393 148.283 138.208 1.00 6.58   ? 207 TYR B CZ  1 
ATOM   1502 O OH  . TYR A 1 228 ? 124.413 149.211 138.449 1.00 17.83  ? 207 TYR B OH  1 
ATOM   1503 N N   . TYR A 1 229 ? 130.007 144.173 135.013 1.00 8.42   ? 208 TYR B N   1 
ATOM   1504 C CA  . TYR A 1 229 ? 131.266 143.625 134.536 1.00 2.47   ? 208 TYR B CA  1 
ATOM   1505 C C   . TYR A 1 229 ? 132.427 144.429 135.101 1.00 7.43   ? 208 TYR B C   1 
ATOM   1506 O O   . TYR A 1 229 ? 132.272 145.574 135.525 1.00 22.35  ? 208 TYR B O   1 
ATOM   1507 C CB  . TYR A 1 229 ? 131.321 143.618 133.007 1.00 3.52   ? 208 TYR B CB  1 
ATOM   1508 C CG  . TYR A 1 229 ? 130.163 142.900 132.362 1.00 8.46   ? 208 TYR B CG  1 
ATOM   1509 C CD1 . TYR A 1 229 ? 129.653 141.734 132.909 1.00 12.76  ? 208 TYR B CD1 1 
ATOM   1510 C CD2 . TYR A 1 229 ? 129.576 143.389 131.209 1.00 10.29  ? 208 TYR B CD2 1 
ATOM   1511 C CE1 . TYR A 1 229 ? 128.594 141.079 132.328 1.00 8.48   ? 208 TYR B CE1 1 
ATOM   1512 C CE2 . TYR A 1 229 ? 128.515 142.739 130.621 1.00 13.64  ? 208 TYR B CE2 1 
ATOM   1513 C CZ  . TYR A 1 229 ? 128.029 141.585 131.183 1.00 12.92  ? 208 TYR B CZ  1 
ATOM   1514 O OH  . TYR A 1 229 ? 126.971 140.932 130.596 1.00 31.32  ? 208 TYR B OH  1 
ATOM   1515 N N   . HIS A 1 230 ? 133.597 143.806 135.114 1.00 1.02   ? 209 HIS B N   1 
ATOM   1516 C CA  . HIS A 1 230 ? 134.778 144.459 135.652 1.00 0.64   ? 209 HIS B CA  1 
ATOM   1517 C C   . HIS A 1 230 ? 135.148 145.665 134.798 1.00 3.87   ? 209 HIS B C   1 
ATOM   1518 O O   . HIS A 1 230 ? 135.163 145.588 133.567 1.00 29.19  ? 209 HIS B O   1 
ATOM   1519 C CB  . HIS A 1 230 ? 135.933 143.465 135.726 1.00 0.00   ? 209 HIS B CB  1 
ATOM   1520 C CG  . HIS A 1 230 ? 135.634 142.261 136.560 1.00 0.40   ? 209 HIS B CG  1 
ATOM   1521 N ND1 . HIS A 1 230 ? 134.790 141.257 136.142 1.00 9.66   ? 209 HIS B ND1 1 
ATOM   1522 C CD2 . HIS A 1 230 ? 136.057 141.905 137.795 1.00 0.00   ? 209 HIS B CD2 1 
ATOM   1523 C CE1 . HIS A 1 230 ? 134.710 140.331 137.081 1.00 5.81   ? 209 HIS B CE1 1 
ATOM   1524 N NE2 . HIS A 1 230 ? 135.471 140.700 138.094 1.00 0.00   ? 209 HIS B NE2 1 
ATOM   1525 N N   . GLY A 1 231 ? 135.441 146.783 135.455 1.00 3.21   ? 210 GLY B N   1 
ATOM   1526 C CA  . GLY A 1 231 ? 135.717 148.030 134.778 1.00 1.26   ? 210 GLY B CA  1 
ATOM   1527 C C   . GLY A 1 231 ? 134.504 148.867 134.436 1.00 7.14   ? 210 GLY B C   1 
ATOM   1528 O O   . GLY A 1 231 ? 134.667 149.976 133.917 1.00 17.74  ? 210 GLY B O   1 
ATOM   1529 N N   . GLU A 1 232 ? 133.324 148.392 134.706 1.00 6.08   ? 211 GLU B N   1 
ATOM   1530 C CA  . GLU A 1 232 ? 132.115 149.129 134.381 1.00 0.33   ? 211 GLU B CA  1 
ATOM   1531 C C   . GLU A 1 232 ? 131.643 149.959 135.570 1.00 16.47  ? 211 GLU B C   1 
ATOM   1532 O O   . GLU A 1 232 ? 131.840 149.571 136.725 1.00 17.79  ? 211 GLU B O   1 
ATOM   1533 C CB  . GLU A 1 232 ? 131.009 148.171 133.964 1.00 3.49   ? 211 GLU B CB  1 
ATOM   1534 C CG  . GLU A 1 232 ? 131.255 147.495 132.636 1.00 14.81  ? 211 GLU B CG  1 
ATOM   1535 C CD  . GLU A 1 232 ? 129.981 147.283 131.858 1.00 22.17  ? 211 GLU B CD  1 
ATOM   1536 O OE1 . GLU A 1 232 ? 128.967 146.896 132.475 1.00 25.68  ? 211 GLU B OE1 1 
ATOM   1537 O OE2 . GLU A 1 232 ? 129.993 147.503 130.629 1.00 14.56  ? 211 GLU B OE2 1 
ATOM   1538 N N   . PRO A 1 233 ? 131.016 151.103 135.311 1.00 17.88  ? 212 PRO B N   1 
ATOM   1539 C CA  . PRO A 1 233 ? 130.540 151.952 136.404 1.00 0.00   ? 212 PRO B CA  1 
ATOM   1540 C C   . PRO A 1 233 ? 129.256 151.434 137.026 1.00 9.83   ? 212 PRO B C   1 
ATOM   1541 O O   . PRO A 1 233 ? 128.388 150.872 136.356 1.00 27.22  ? 212 PRO B O   1 
ATOM   1542 C CB  . PRO A 1 233 ? 130.304 153.299 135.715 1.00 4.67   ? 212 PRO B CB  1 
ATOM   1543 C CG  . PRO A 1 233 ? 129.964 152.932 134.325 1.00 8.58   ? 212 PRO B CG  1 
ATOM   1544 C CD  . PRO A 1 233 ? 130.790 151.724 133.996 1.00 11.05  ? 212 PRO B CD  1 
ATOM   1545 N N   . ILE A 1 234 ? 129.140 151.653 138.331 1.00 0.00   ? 213 ILE B N   1 
ATOM   1546 C CA  . ILE A 1 234 ? 127.961 151.285 139.102 1.00 0.00   ? 213 ILE B CA  1 
ATOM   1547 C C   . ILE A 1 234 ? 127.248 152.571 139.492 1.00 0.00   ? 213 ILE B C   1 
ATOM   1548 O O   . ILE A 1 234 ? 127.800 153.393 140.230 1.00 21.55  ? 213 ILE B O   1 
ATOM   1549 C CB  . ILE A 1 234 ? 128.336 150.455 140.338 1.00 0.00   ? 213 ILE B CB  1 
ATOM   1550 C CG1 . ILE A 1 234 ? 129.292 149.329 139.944 1.00 0.00   ? 213 ILE B CG1 1 
ATOM   1551 C CG2 . ILE A 1 234 ? 127.100 149.896 141.009 1.00 0.00   ? 213 ILE B CG2 1 
ATOM   1552 C CD1 . ILE A 1 234 ? 129.945 148.647 141.102 1.00 0.00   ? 213 ILE B CD1 1 
ATOM   1553 N N   . SER A 1 235 ? 126.029 152.749 138.999 1.00 1.98   ? 214 SER B N   1 
ATOM   1554 C CA  . SER A 1 235 ? 125.258 153.962 139.238 1.00 1.38   ? 214 SER B CA  1 
ATOM   1555 C C   . SER A 1 235 ? 124.287 153.725 140.386 1.00 17.67  ? 214 SER B C   1 
ATOM   1556 O O   . SER A 1 235 ? 123.440 152.829 140.311 1.00 34.73  ? 214 SER B O   1 
ATOM   1557 C CB  . SER A 1 235 ? 124.505 154.385 137.979 1.00 15.76  ? 214 SER B CB  1 
ATOM   1558 O OG  . SER A 1 235 ? 125.320 155.189 137.145 1.00 27.22  ? 214 SER B OG  1 
ATOM   1559 N N   . VAL A 1 236 ? 124.400 154.535 141.434 1.00 11.43  ? 215 VAL B N   1 
ATOM   1560 C CA  . VAL A 1 236 ? 123.574 154.416 142.627 1.00 3.72   ? 215 VAL B CA  1 
ATOM   1561 C C   . VAL A 1 236 ? 122.577 155.563 142.633 1.00 16.07  ? 215 VAL B C   1 
ATOM   1562 O O   . VAL A 1 236 ? 122.969 156.731 142.555 1.00 31.82  ? 215 VAL B O   1 
ATOM   1563 C CB  . VAL A 1 236 ? 124.427 154.427 143.906 1.00 11.44  ? 215 VAL B CB  1 
ATOM   1564 C CG1 . VAL A 1 236 ? 123.636 153.863 145.070 1.00 24.72  ? 215 VAL B CG1 1 
ATOM   1565 C CG2 . VAL A 1 236 ? 125.717 153.652 143.691 1.00 4.67   ? 215 VAL B CG2 1 
ATOM   1566 N N   . ASN A 1 237 ? 121.296 155.233 142.728 1.00 15.13  ? 216 ASN B N   1 
ATOM   1567 C CA  . ASN A 1 237 ? 120.226 156.229 142.707 1.00 12.76  ? 216 ASN B CA  1 
ATOM   1568 C C   . ASN A 1 237 ? 119.757 156.453 144.139 1.00 26.77  ? 216 ASN B C   1 
ATOM   1569 O O   . ASN A 1 237 ? 118.804 155.829 144.602 1.00 41.51  ? 216 ASN B O   1 
ATOM   1570 C CB  . ASN A 1 237 ? 119.086 155.774 141.807 1.00 20.59  ? 216 ASN B CB  1 
ATOM   1571 C CG  . ASN A 1 237 ? 118.046 156.850 141.602 1.00 30.38  ? 216 ASN B CG  1 
ATOM   1572 O OD1 . ASN A 1 237 ? 118.051 157.545 140.588 1.00 37.70  ? 216 ASN B OD1 1 
ATOM   1573 N ND2 . ASN A 1 237 ? 117.143 156.991 142.562 1.00 31.40  ? 216 ASN B ND2 1 
ATOM   1574 N N   . VAL A 1 238 ? 120.422 157.367 144.837 1.00 12.00  ? 217 VAL B N   1 
ATOM   1575 C CA  . VAL A 1 238 ? 120.107 157.670 146.227 1.00 2.39   ? 217 VAL B CA  1 
ATOM   1576 C C   . VAL A 1 238 ? 119.023 158.735 146.269 1.00 12.29  ? 217 VAL B C   1 
ATOM   1577 O O   . VAL A 1 238 ? 119.127 159.768 145.599 1.00 27.27  ? 217 VAL B O   1 
ATOM   1578 C CB  . VAL A 1 238 ? 121.360 158.133 146.984 1.00 9.85   ? 217 VAL B CB  1 
ATOM   1579 C CG1 . VAL A 1 238 ? 121.061 158.268 148.463 1.00 20.75  ? 217 VAL B CG1 1 
ATOM   1580 C CG2 . VAL A 1 238 ? 122.491 157.162 146.755 1.00 19.07  ? 217 VAL B CG2 1 
ATOM   1581 N N   . HIS A 1 239 ? 117.978 158.487 147.055 1.00 15.40  ? 218 HIS B N   1 
ATOM   1582 C CA  . HIS A 1 239 ? 116.867 159.427 147.194 1.00 14.86  ? 218 HIS B CA  1 
ATOM   1583 C C   . HIS A 1 239 ? 116.527 159.539 148.676 1.00 25.92  ? 218 HIS B C   1 
ATOM   1584 O O   . HIS A 1 239 ? 115.856 158.666 149.233 1.00 34.81  ? 218 HIS B O   1 
ATOM   1585 C CB  . HIS A 1 239 ? 115.662 158.984 146.376 1.00 21.14  ? 218 HIS B CB  1 
ATOM   1586 C CG  . HIS A 1 239 ? 114.408 159.737 146.693 1.00 32.32  ? 218 HIS B CG  1 
ATOM   1587 N ND1 . HIS A 1 239 ? 114.408 161.066 147.057 1.00 35.77  ? 218 HIS B ND1 1 
ATOM   1588 C CD2 . HIS A 1 239 ? 113.111 159.348 146.695 1.00 32.82  ? 218 HIS B CD2 1 
ATOM   1589 C CE1 . HIS A 1 239 ? 113.167 161.461 147.275 1.00 33.17  ? 218 HIS B CE1 1 
ATOM   1590 N NE2 . HIS A 1 239 ? 112.361 160.438 147.062 1.00 35.29  ? 218 HIS B NE2 1 
ATOM   1591 N N   . VAL A 1 240 ? 116.976 160.624 149.301 1.00 31.81  ? 219 VAL B N   1 
ATOM   1592 C CA  . VAL A 1 240 ? 116.771 160.877 150.721 1.00 23.43  ? 219 VAL B CA  1 
ATOM   1593 C C   . VAL A 1 240 ? 115.583 161.808 150.897 1.00 27.19  ? 219 VAL B C   1 
ATOM   1594 O O   . VAL A 1 240 ? 115.298 162.656 150.045 1.00 42.91  ? 219 VAL B O   1 
ATOM   1595 C CB  . VAL A 1 240 ? 118.041 161.476 151.357 1.00 17.58  ? 219 VAL B CB  1 
ATOM   1596 C CG1 . VAL A 1 240 ? 117.921 161.502 152.865 1.00 22.79  ? 219 VAL B CG1 1 
ATOM   1597 C CG2 . VAL A 1 240 ? 119.267 160.693 150.919 1.00 19.02  ? 219 VAL B CG2 1 
ATOM   1598 N N   . THR A 1 241 ? 114.868 161.642 152.010 1.00 19.40  ? 220 THR B N   1 
ATOM   1599 C CA  . THR A 1 241 ? 113.807 162.579 152.390 1.00 26.66  ? 220 THR B CA  1 
ATOM   1600 C C   . THR A 1 241 ? 113.760 162.641 153.920 1.00 30.09  ? 220 THR B C   1 
ATOM   1601 O O   . THR A 1 241 ? 113.113 161.821 154.574 1.00 35.55  ? 220 THR B O   1 
ATOM   1602 C CB  . THR A 1 241 ? 112.463 162.197 151.778 1.00 28.67  ? 220 THR B CB  1 
ATOM   1603 O OG1 . THR A 1 241 ? 111.421 163.002 152.343 1.00 33.30  ? 220 THR B OG1 1 
ATOM   1604 C CG2 . THR A 1 241 ? 112.152 160.726 151.953 1.00 32.56  ? 220 THR B CG2 1 
ATOM   1605 N N   . ASN A 1 242 ? 114.454 163.633 154.477 1.00 36.63  ? 221 ASN B N   1 
ATOM   1606 C CA  . ASN A 1 242 ? 114.564 163.805 155.925 1.00 35.10  ? 221 ASN B CA  1 
ATOM   1607 C C   . ASN A 1 242 ? 113.402 164.662 156.404 1.00 37.12  ? 221 ASN B C   1 
ATOM   1608 O O   . ASN A 1 242 ? 113.519 165.877 156.556 1.00 42.98  ? 221 ASN B O   1 
ATOM   1609 C CB  . ASN A 1 242 ? 115.903 164.429 156.293 1.00 29.21  ? 221 ASN B CB  1 
ATOM   1610 N N   . ASN A 1 243 ? 112.268 164.018 156.665 1.00 47.50  ? 222 ASN B N   1 
ATOM   1611 C CA  . ASN A 1 243 ? 111.085 164.706 157.164 1.00 45.94  ? 222 ASN B CA  1 
ATOM   1612 C C   . ASN A 1 243 ? 111.171 165.024 158.650 1.00 49.04  ? 222 ASN B C   1 
ATOM   1613 O O   . ASN A 1 243 ? 110.182 165.486 159.226 1.00 51.73  ? 222 ASN B O   1 
ATOM   1614 C CB  . ASN A 1 243 ? 109.832 163.872 156.889 1.00 44.53  ? 222 ASN B CB  1 
ATOM   1615 N N   . THR A 1 244 ? 112.316 164.784 159.278 1.00 52.36  ? 223 THR B N   1 
ATOM   1616 C CA  . THR A 1 244 ? 112.513 165.039 160.693 1.00 51.26  ? 223 THR B CA  1 
ATOM   1617 C C   . THR A 1 244 ? 113.173 166.403 160.884 1.00 54.79  ? 223 THR B C   1 
ATOM   1618 O O   . THR A 1 244 ? 113.354 167.171 159.936 1.00 54.54  ? 223 THR B O   1 
ATOM   1619 C CB  . THR A 1 244 ? 113.345 163.919 161.318 1.00 49.51  ? 223 THR B CB  1 
ATOM   1620 N N   . ASN A 1 245 ? 113.537 166.714 162.128 1.00 57.85  ? 224 ASN B N   1 
ATOM   1621 C CA  . ASN A 1 245 ? 114.201 167.967 162.466 1.00 58.13  ? 224 ASN B CA  1 
ATOM   1622 C C   . ASN A 1 245 ? 115.709 167.800 162.621 1.00 56.81  ? 224 ASN B C   1 
ATOM   1623 O O   . ASN A 1 245 ? 116.343 168.551 163.369 1.00 55.16  ? 224 ASN B O   1 
ATOM   1624 C CB  . ASN A 1 245 ? 113.598 168.557 163.741 1.00 54.83  ? 224 ASN B CB  1 
ATOM   1625 N N   . LYS A 1 246 ? 116.294 166.828 161.928 1.00 49.52  ? 225 LYS B N   1 
ATOM   1626 C CA  . LYS A 1 246 ? 117.724 166.573 161.980 1.00 47.34  ? 225 LYS B CA  1 
ATOM   1627 C C   . LYS A 1 246 ? 118.328 166.762 160.595 1.00 51.46  ? 225 LYS B C   1 
ATOM   1628 O O   . LYS A 1 246 ? 117.687 166.483 159.577 1.00 53.69  ? 225 LYS B O   1 
ATOM   1629 C CB  . LYS A 1 246 ? 118.014 165.161 162.494 1.00 45.31  ? 225 LYS B CB  1 
ATOM   1630 N N   . THR A 1 247 ? 119.570 167.236 160.563 1.00 47.64  ? 226 THR B N   1 
ATOM   1631 C CA  . THR A 1 247 ? 120.244 167.586 159.320 1.00 45.59  ? 226 THR B CA  1 
ATOM   1632 C C   . THR A 1 247 ? 121.248 166.504 158.946 1.00 50.62  ? 226 THR B C   1 
ATOM   1633 O O   . THR A 1 247 ? 122.055 166.084 159.782 1.00 52.10  ? 226 THR B O   1 
ATOM   1634 C CB  . THR A 1 247 ? 120.950 168.937 159.446 1.00 46.66  ? 226 THR B CB  1 
ATOM   1635 O OG1 . THR A 1 247 ? 119.973 169.985 159.506 1.00 50.51  ? 226 THR B OG1 1 
ATOM   1636 C CG2 . THR A 1 247 ? 121.870 169.181 158.260 1.00 42.46  ? 226 THR B CG2 1 
ATOM   1637 N N   . VAL A 1 248 ? 121.192 166.058 157.694 1.00 46.83  ? 227 VAL B N   1 
ATOM   1638 C CA  . VAL A 1 248 ? 122.143 165.081 157.171 1.00 43.96  ? 227 VAL B CA  1 
ATOM   1639 C C   . VAL A 1 248 ? 123.439 165.817 156.853 1.00 43.04  ? 227 VAL B C   1 
ATOM   1640 O O   . VAL A 1 248 ? 123.486 166.647 155.943 1.00 43.62  ? 227 VAL B O   1 
ATOM   1641 C CB  . VAL A 1 248 ? 121.594 164.367 155.932 1.00 42.18  ? 227 VAL B CB  1 
ATOM   1642 C CG1 . VAL A 1 248 ? 122.627 163.402 155.381 1.00 39.65  ? 227 VAL B CG1 1 
ATOM   1643 C CG2 . VAL A 1 248 ? 120.298 163.643 156.261 1.00 36.40  ? 227 VAL B CG2 1 
ATOM   1644 N N   . LYS A 1 249 ? 124.496 165.517 157.608 1.00 43.72  ? 228 LYS B N   1 
ATOM   1645 C CA  . LYS A 1 249 ? 125.753 166.235 157.427 1.00 42.86  ? 228 LYS B CA  1 
ATOM   1646 C C   . LYS A 1 249 ? 126.482 165.778 156.169 1.00 43.80  ? 228 LYS B C   1 
ATOM   1647 O O   . LYS A 1 249 ? 127.038 166.603 155.436 1.00 46.79  ? 228 LYS B O   1 
ATOM   1648 C CB  . LYS A 1 249 ? 126.636 166.054 158.663 1.00 42.54  ? 228 LYS B CB  1 
ATOM   1649 C CG  . LYS A 1 249 ? 128.129 166.065 158.382 1.00 43.99  ? 228 LYS B CG  1 
ATOM   1650 C CD  . LYS A 1 249 ? 128.706 167.458 158.579 1.00 46.51  ? 228 LYS B CD  1 
ATOM   1651 C CE  . LYS A 1 249 ? 129.922 167.692 157.702 1.00 44.61  ? 228 LYS B CE  1 
ATOM   1652 N NZ  . LYS A 1 249 ? 130.091 169.136 157.382 1.00 41.02  ? 228 LYS B NZ  1 
ATOM   1653 N N   . LYS A 1 250 ? 126.484 164.476 155.897 1.00 37.80  ? 229 LYS B N   1 
ATOM   1654 C CA  . LYS A 1 250 ? 127.294 163.932 154.817 1.00 36.55  ? 229 LYS B CA  1 
ATOM   1655 C C   . LYS A 1 250 ? 126.677 162.625 154.340 1.00 39.71  ? 229 LYS B C   1 
ATOM   1656 O O   . LYS A 1 250 ? 125.910 161.982 155.058 1.00 46.14  ? 229 LYS B O   1 
ATOM   1657 C CB  . LYS A 1 250 ? 128.741 163.719 155.274 1.00 39.19  ? 229 LYS B CB  1 
ATOM   1658 C CG  . LYS A 1 250 ? 129.749 163.538 154.156 1.00 39.11  ? 229 LYS B CG  1 
ATOM   1659 C CD  . LYS A 1 250 ? 131.048 164.257 154.462 1.00 43.89  ? 229 LYS B CD  1 
ATOM   1660 C CE  . LYS A 1 250 ? 131.453 164.082 155.916 1.00 44.21  ? 229 LYS B CE  1 
ATOM   1661 N NZ  . LYS A 1 250 ? 131.603 162.651 156.294 1.00 41.26  ? 229 LYS B NZ  1 
ATOM   1662 N N   . ILE A 1 251 ? 127.020 162.246 153.111 1.00 38.48  ? 230 ILE B N   1 
ATOM   1663 C CA  . ILE A 1 251 ? 126.557 161.006 152.498 1.00 34.64  ? 230 ILE B CA  1 
ATOM   1664 C C   . ILE A 1 251 ? 127.775 160.218 152.043 1.00 34.06  ? 230 ILE B C   1 
ATOM   1665 O O   . ILE A 1 251 ? 128.575 160.711 151.239 1.00 39.25  ? 230 ILE B O   1 
ATOM   1666 C CB  . ILE A 1 251 ? 125.609 161.271 151.320 1.00 32.16  ? 230 ILE B CB  1 
ATOM   1667 C CG1 . ILE A 1 251 ? 124.502 162.236 151.741 1.00 30.95  ? 230 ILE B CG1 1 
ATOM   1668 C CG2 . ILE A 1 251 ? 125.031 159.966 150.801 1.00 33.41  ? 230 ILE B CG2 1 
ATOM   1669 C CD1 . ILE A 1 251 ? 123.390 162.353 150.741 1.00 33.67  ? 230 ILE B CD1 1 
ATOM   1670 N N   . LYS A 1 252 ? 127.910 158.994 152.543 1.00 34.57  ? 231 LYS B N   1 
ATOM   1671 C CA  . LYS A 1 252 ? 129.022 158.119 152.201 1.00 31.76  ? 231 LYS B CA  1 
ATOM   1672 C C   . LYS A 1 252 ? 128.510 156.966 151.352 1.00 37.92  ? 231 LYS B C   1 
ATOM   1673 O O   . LYS A 1 252 ? 127.536 156.304 151.722 1.00 33.22  ? 231 LYS B O   1 
ATOM   1674 C CB  . LYS A 1 252 ? 129.706 157.582 153.458 1.00 39.39  ? 231 LYS B CB  1 
ATOM   1675 C CG  . LYS A 1 252 ? 130.090 158.648 154.462 1.00 41.05  ? 231 LYS B CG  1 
ATOM   1676 C CD  . LYS A 1 252 ? 131.130 158.132 155.440 1.00 38.69  ? 231 LYS B CD  1 
ATOM   1677 C CE  . LYS A 1 252 ? 130.579 158.082 156.852 1.00 39.07  ? 231 LYS B CE  1 
ATOM   1678 N NZ  . LYS A 1 252 ? 130.982 159.273 157.646 1.00 37.03  ? 231 LYS B NZ  1 
ATOM   1679 N N   . ILE A 1 253 ? 129.166 156.730 150.220 1.00 42.85  ? 232 ILE B N   1 
ATOM   1680 C CA  . ILE A 1 253 ? 128.766 155.697 149.274 1.00 21.25  ? 232 ILE B CA  1 
ATOM   1681 C C   . ILE A 1 253 ? 129.961 154.774 149.088 1.00 23.60  ? 232 ILE B C   1 
ATOM   1682 O O   . ILE A 1 253 ? 131.049 155.233 148.719 1.00 24.63  ? 232 ILE B O   1 
ATOM   1683 C CB  . ILE A 1 253 ? 128.336 156.298 147.930 1.00 18.00  ? 232 ILE B CB  1 
ATOM   1684 C CG1 . ILE A 1 253 ? 127.080 157.148 148.097 1.00 16.11  ? 232 ILE B CG1 1 
ATOM   1685 C CG2 . ILE A 1 253 ? 128.040 155.190 146.960 1.00 32.00  ? 232 ILE B CG2 1 
ATOM   1686 C CD1 . ILE A 1 253 ? 125.809 156.386 148.042 1.00 26.09  ? 232 ILE B CD1 1 
ATOM   1687 N N   . SER A 1 254 ? 129.768 153.480 149.332 1.00 32.47  ? 233 SER B N   1 
ATOM   1688 C CA  . SER A 1 254 ? 130.885 152.547 149.315 1.00 28.64  ? 233 SER B CA  1 
ATOM   1689 C C   . SER A 1 254 ? 130.511 151.256 148.604 1.00 20.10  ? 233 SER B C   1 
ATOM   1690 O O   . SER A 1 254 ? 129.377 150.783 148.709 1.00 24.66  ? 233 SER B O   1 
ATOM   1691 C CB  . SER A 1 254 ? 131.361 152.225 150.735 1.00 26.76  ? 233 SER B CB  1 
ATOM   1692 O OG  . SER A 1 254 ? 132.664 151.673 150.721 1.00 36.60  ? 233 SER B OG  1 
ATOM   1693 N N   . VAL A 1 255 ? 131.481 150.696 147.885 1.00 20.98  ? 234 VAL B N   1 
ATOM   1694 C CA  . VAL A 1 255 ? 131.410 149.349 147.330 1.00 25.04  ? 234 VAL B CA  1 
ATOM   1695 C C   . VAL A 1 255 ? 132.380 148.489 148.125 1.00 18.68  ? 234 VAL B C   1 
ATOM   1696 O O   . VAL A 1 255 ? 133.567 148.820 148.231 1.00 18.99  ? 234 VAL B O   1 
ATOM   1697 C CB  . VAL A 1 255 ? 131.756 149.323 145.832 1.00 25.96  ? 234 VAL B CB  1 
ATOM   1698 C CG1 . VAL A 1 255 ? 131.733 147.898 145.310 1.00 12.15  ? 234 VAL B CG1 1 
ATOM   1699 C CG2 . VAL A 1 255 ? 130.797 150.188 145.042 1.00 18.83  ? 234 VAL B CG2 1 
ATOM   1700 N N   . ARG A 1 256 ? 131.882 147.393 148.688 1.00 15.02  ? 235 ARG B N   1 
ATOM   1701 C CA  . ARG A 1 256 ? 132.684 146.539 149.549 1.00 13.17  ? 235 ARG B CA  1 
ATOM   1702 C C   . ARG A 1 256 ? 132.652 145.104 149.048 1.00 17.92  ? 235 ARG B C   1 
ATOM   1703 O O   . ARG A 1 256 ? 131.655 144.643 148.489 1.00 17.28  ? 235 ARG B O   1 
ATOM   1704 C CB  . ARG A 1 256 ? 132.198 146.593 150.999 1.00 17.16  ? 235 ARG B CB  1 
ATOM   1705 C CG  . ARG A 1 256 ? 130.704 146.416 151.148 1.00 28.87  ? 235 ARG B CG  1 
ATOM   1706 C CD  . ARG A 1 256 ? 130.064 147.653 151.731 1.00 21.21  ? 235 ARG B CD  1 
ATOM   1707 N NE  . ARG A 1 256 ? 131.029 148.479 152.446 1.00 19.79  ? 235 ARG B NE  1 
ATOM   1708 C CZ  . ARG A 1 256 ? 131.073 148.602 153.765 1.00 32.02  ? 235 ARG B CZ  1 
ATOM   1709 N NH1 . ARG A 1 256 ? 130.230 147.950 154.548 1.00 25.44  ? 235 ARG B NH1 1 
ATOM   1710 N NH2 . ARG A 1 256 ? 131.984 149.401 154.312 1.00 30.53  ? 235 ARG B NH2 1 
ATOM   1711 N N   . GLN A 1 257 ? 133.760 144.404 149.260 1.00 13.85  ? 236 GLN B N   1 
ATOM   1712 C CA  . GLN A 1 257 ? 133.909 143.009 148.877 1.00 7.29   ? 236 GLN B CA  1 
ATOM   1713 C C   . GLN A 1 257 ? 133.953 142.139 150.125 1.00 22.39  ? 236 GLN B C   1 
ATOM   1714 O O   . GLN A 1 257 ? 134.760 142.383 151.027 1.00 25.79  ? 236 GLN B O   1 
ATOM   1715 C CB  . GLN A 1 257 ? 135.180 142.805 148.055 1.00 6.29   ? 236 GLN B CB  1 
ATOM   1716 C CG  . GLN A 1 257 ? 135.421 141.373 147.625 1.00 9.99   ? 236 GLN B CG  1 
ATOM   1717 C CD  . GLN A 1 257 ? 136.881 141.088 147.374 1.00 16.32  ? 236 GLN B CD  1 
ATOM   1718 O OE1 . GLN A 1 257 ? 137.626 140.764 148.294 1.00 16.10  ? 236 GLN B OE1 1 
ATOM   1719 N NE2 . GLN A 1 257 ? 137.303 141.218 146.125 1.00 20.99  ? 236 GLN B NE2 1 
ATOM   1720 N N   . TYR A 1 258 ? 133.094 141.128 150.168 1.00 17.45  ? 237 TYR B N   1 
ATOM   1721 C CA  . TYR A 1 258 ? 133.085 140.139 151.232 1.00 8.28   ? 237 TYR B CA  1 
ATOM   1722 C C   . TYR A 1 258 ? 133.709 138.842 150.743 1.00 15.56  ? 237 TYR B C   1 
ATOM   1723 O O   . TYR A 1 258 ? 133.564 138.465 149.579 1.00 29.99  ? 237 TYR B O   1 
ATOM   1724 C CB  . TYR A 1 258 ? 131.666 139.869 151.725 1.00 15.26  ? 237 TYR B CB  1 
ATOM   1725 C CG  . TYR A 1 258 ? 130.904 141.114 152.090 1.00 25.63  ? 237 TYR B CG  1 
ATOM   1726 C CD1 . TYR A 1 258 ? 130.999 141.658 153.362 1.00 31.22  ? 237 TYR B CD1 1 
ATOM   1727 C CD2 . TYR A 1 258 ? 130.091 141.744 151.168 1.00 22.22  ? 237 TYR B CD2 1 
ATOM   1728 C CE1 . TYR A 1 258 ? 130.305 142.794 153.702 1.00 22.75  ? 237 TYR B CE1 1 
ATOM   1729 C CE2 . TYR A 1 258 ? 129.397 142.881 151.500 1.00 25.84  ? 237 TYR B CE2 1 
ATOM   1730 C CZ  . TYR A 1 258 ? 129.505 143.402 152.767 1.00 27.48  ? 237 TYR B CZ  1 
ATOM   1731 O OH  . TYR A 1 258 ? 128.807 144.538 153.099 1.00 36.14  ? 237 TYR B OH  1 
ATOM   1732 N N   . ALA A 1 259 ? 134.407 138.158 151.645 1.00 24.89  ? 238 ALA B N   1 
ATOM   1733 C CA  . ALA A 1 259 ? 135.087 136.903 151.318 1.00 22.81  ? 238 ALA B CA  1 
ATOM   1734 C C   . ALA A 1 259 ? 134.910 135.944 152.493 1.00 21.68  ? 238 ALA B C   1 
ATOM   1735 O O   . ALA A 1 259 ? 135.685 135.972 153.451 1.00 33.49  ? 238 ALA B O   1 
ATOM   1736 C CB  . ALA A 1 259 ? 136.557 137.144 151.007 1.00 21.85  ? 238 ALA B CB  1 
ATOM   1737 N N   . ASP A 1 260 ? 133.888 135.096 152.412 1.00 17.61  ? 239 ASP B N   1 
ATOM   1738 C CA  . ASP A 1 260 ? 133.725 134.032 153.393 1.00 29.90  ? 239 ASP B CA  1 
ATOM   1739 C C   . ASP A 1 260 ? 134.811 132.982 153.201 1.00 31.43  ? 239 ASP B C   1 
ATOM   1740 O O   . ASP A 1 260 ? 135.071 132.542 152.079 1.00 34.19  ? 239 ASP B O   1 
ATOM   1741 C CB  . ASP A 1 260 ? 132.347 133.392 153.263 1.00 23.87  ? 239 ASP B CB  1 
ATOM   1742 C CG  . ASP A 1 260 ? 131.232 134.394 153.400 1.00 27.60  ? 239 ASP B CG  1 
ATOM   1743 O OD1 . ASP A 1 260 ? 131.526 135.606 153.393 1.00 29.82  ? 239 ASP B OD1 1 
ATOM   1744 O OD2 . ASP A 1 260 ? 130.064 133.972 153.520 1.00 34.31  ? 239 ASP B OD2 1 
ATOM   1745 N N   . ILE A 1 261 ? 135.446 132.578 154.296 1.00 33.39  ? 240 ILE B N   1 
ATOM   1746 C CA  . ILE A 1 261 ? 136.549 131.624 154.263 1.00 34.56  ? 240 ILE B CA  1 
ATOM   1747 C C   . ILE A 1 261 ? 136.246 130.551 155.301 1.00 43.55  ? 240 ILE B C   1 
ATOM   1748 O O   . ILE A 1 261 ? 136.472 130.755 156.498 1.00 51.22  ? 240 ILE B O   1 
ATOM   1749 C CB  . ILE A 1 261 ? 137.901 132.290 154.532 1.00 37.34  ? 240 ILE B CB  1 
ATOM   1750 C CG1 . ILE A 1 261 ? 138.222 133.299 153.431 1.00 31.60  ? 240 ILE B CG1 1 
ATOM   1751 C CG2 . ILE A 1 261 ? 138.992 131.249 154.630 1.00 46.45  ? 240 ILE B CG2 1 
ATOM   1752 C CD1 . ILE A 1 261 ? 139.378 134.206 153.754 1.00 37.41  ? 240 ILE B CD1 1 
ATOM   1753 N N   . CYS A 1 262 ? 135.732 129.411 154.852 1.00 58.59  ? 241 CYS B N   1 
ATOM   1754 C CA  . CYS A 1 262 ? 135.421 128.294 155.743 1.00 64.22  ? 241 CYS B CA  1 
ATOM   1755 C C   . CYS A 1 262 ? 136.554 127.267 155.737 1.00 66.40  ? 241 CYS B C   1 
ATOM   1756 O O   . CYS A 1 262 ? 136.382 126.112 155.356 1.00 64.84  ? 241 CYS B O   1 
ATOM   1757 C CB  . CYS A 1 262 ? 134.093 127.657 155.341 1.00 63.95  ? 241 CYS B CB  1 
ATOM   1758 S SG  . CYS A 1 262 ? 133.509 126.345 156.440 1.00 69.16  ? 241 CYS B SG  1 
ATOM   1759 N N   . LEU A 1 263 ? 137.733 127.697 156.185 1.00 72.15  ? 242 LEU B N   1 
ATOM   1760 C CA  . LEU A 1 263 ? 138.891 126.807 156.211 1.00 73.27  ? 242 LEU B CA  1 
ATOM   1761 C C   . LEU A 1 263 ? 138.984 126.056 157.536 1.00 74.75  ? 242 LEU B C   1 
ATOM   1762 O O   . LEU A 1 263 ? 138.905 124.825 157.569 1.00 75.27  ? 242 LEU B O   1 
ATOM   1763 C CB  . LEU A 1 263 ? 140.175 127.602 155.949 1.00 72.31  ? 242 LEU B CB  1 
ATOM   1764 C CG  . LEU A 1 263 ? 141.476 126.797 156.012 1.00 72.28  ? 242 LEU B CG  1 
ATOM   1765 C CD1 . LEU A 1 263 ? 142.330 127.067 154.788 1.00 71.82  ? 242 LEU B CD1 1 
ATOM   1766 C CD2 . LEU A 1 263 ? 142.254 127.105 157.286 1.00 70.91  ? 242 LEU B CD2 1 
ATOM   1767 N N   . PHE A 1 264 ? 139.150 126.791 158.633 1.00 85.23  ? 243 PHE B N   1 
ATOM   1768 C CA  . PHE A 1 264 ? 139.141 126.223 159.973 1.00 86.22  ? 243 PHE B CA  1 
ATOM   1769 C C   . PHE A 1 264 ? 137.898 126.596 160.761 1.00 86.46  ? 243 PHE B C   1 
ATOM   1770 O O   . PHE A 1 264 ? 137.438 125.802 161.583 1.00 84.52  ? 243 PHE B O   1 
ATOM   1771 C CB  . PHE A 1 264 ? 140.384 126.677 160.749 1.00 86.43  ? 243 PHE B CB  1 
ATOM   1772 C CG  . PHE A 1 264 ? 140.586 125.960 162.052 1.00 88.56  ? 243 PHE B CG  1 
ATOM   1773 C CD1 . PHE A 1 264 ? 140.405 124.591 162.141 1.00 87.91  ? 243 PHE B CD1 1 
ATOM   1774 C CD2 . PHE A 1 264 ? 140.960 126.657 163.188 1.00 84.93  ? 243 PHE B CD2 1 
ATOM   1775 C CE1 . PHE A 1 264 ? 140.592 123.931 163.341 1.00 85.43  ? 243 PHE B CE1 1 
ATOM   1776 C CE2 . PHE A 1 264 ? 141.148 126.004 164.390 1.00 84.44  ? 243 PHE B CE2 1 
ATOM   1777 C CZ  . PHE A 1 264 ? 140.964 124.639 164.467 1.00 85.23  ? 243 PHE B CZ  1 
ATOM   1778 N N   . ASN A 1 265 ? 137.350 127.783 160.519 1.00 85.35  ? 244 ASN B N   1 
ATOM   1779 C CA  . ASN A 1 265 ? 136.079 128.202 161.085 1.00 86.01  ? 244 ASN B CA  1 
ATOM   1780 C C   . ASN A 1 265 ? 135.461 129.214 160.133 1.00 85.35  ? 244 ASN B C   1 
ATOM   1781 O O   . ASN A 1 265 ? 136.177 129.994 159.501 1.00 83.99  ? 244 ASN B O   1 
ATOM   1782 C CB  . ASN A 1 265 ? 136.254 128.809 162.481 1.00 83.48  ? 244 ASN B CB  1 
ATOM   1783 N N   . THR A 1 266 ? 134.133 129.188 160.028 1.00 79.90  ? 245 THR B N   1 
ATOM   1784 C CA  . THR A 1 266 ? 133.426 130.113 159.150 1.00 76.78  ? 245 THR B CA  1 
ATOM   1785 C C   . THR A 1 266 ? 133.696 131.550 159.574 1.00 77.79  ? 245 THR B C   1 
ATOM   1786 O O   . THR A 1 266 ? 133.282 131.971 160.659 1.00 78.02  ? 245 THR B O   1 
ATOM   1787 C CB  . THR A 1 266 ? 131.924 129.829 159.163 1.00 79.44  ? 245 THR B CB  1 
ATOM   1788 O OG1 . THR A 1 266 ? 131.411 130.032 160.486 1.00 85.17  ? 245 THR B OG1 1 
ATOM   1789 C CG2 . THR A 1 266 ? 131.649 128.397 158.735 1.00 74.86  ? 245 THR B CG2 1 
ATOM   1790 N N   . ALA A 1 267 ? 134.392 132.308 158.730 1.00 61.67  ? 246 ALA B N   1 
ATOM   1791 C CA  . ALA A 1 267 ? 134.793 133.673 159.057 1.00 61.20  ? 246 ALA B CA  1 
ATOM   1792 C C   . ALA A 1 267 ? 134.551 134.557 157.843 1.00 59.85  ? 246 ALA B C   1 
ATOM   1793 O O   . ALA A 1 267 ? 135.275 134.457 156.849 1.00 54.40  ? 246 ALA B O   1 
ATOM   1794 C CB  . ALA A 1 267 ? 136.259 133.728 159.485 1.00 57.81  ? 246 ALA B CB  1 
ATOM   1795 N N   . GLN A 1 268 ? 133.544 135.424 157.926 1.00 54.62  ? 247 GLN B N   1 
ATOM   1796 C CA  . GLN A 1 268 ? 133.259 136.369 156.854 1.00 48.39  ? 247 GLN B CA  1 
ATOM   1797 C C   . GLN A 1 268 ? 134.155 137.591 156.993 1.00 45.05  ? 247 GLN B C   1 
ATOM   1798 O O   . GLN A 1 268 ? 134.198 138.216 158.057 1.00 50.84  ? 247 GLN B O   1 
ATOM   1799 C CB  . GLN A 1 268 ? 131.794 136.791 156.877 1.00 48.00  ? 247 GLN B CB  1 
ATOM   1800 C CG  . GLN A 1 268 ? 131.530 138.046 156.059 1.00 52.54  ? 247 GLN B CG  1 
ATOM   1801 C CD  . GLN A 1 268 ? 130.076 138.206 155.671 1.00 48.85  ? 247 GLN B CD  1 
ATOM   1802 O OE1 . GLN A 1 268 ? 129.294 138.819 156.397 1.00 48.48  ? 247 GLN B OE1 1 
ATOM   1803 N NE2 . GLN A 1 268 ? 129.706 137.659 154.520 1.00 42.17  ? 247 GLN B NE2 1 
ATOM   1804 N N   . TYR A 1 269 ? 134.861 137.933 155.922 1.00 41.73  ? 248 TYR B N   1 
ATOM   1805 C CA  . TYR A 1 269 ? 135.670 139.137 155.871 1.00 41.69  ? 248 TYR B CA  1 
ATOM   1806 C C   . TYR A 1 269 ? 134.951 140.194 155.038 1.00 41.36  ? 248 TYR B C   1 
ATOM   1807 O O   . TYR A 1 269 ? 133.878 139.961 154.479 1.00 46.25  ? 248 TYR B O   1 
ATOM   1808 C CB  . TYR A 1 269 ? 137.066 138.844 155.318 1.00 41.61  ? 248 TYR B CB  1 
ATOM   1809 C CG  . TYR A 1 269 ? 137.912 137.927 156.179 1.00 49.24  ? 248 TYR B CG  1 
ATOM   1810 C CD1 . TYR A 1 269 ? 137.453 136.677 156.572 1.00 47.84  ? 248 TYR B CD1 1 
ATOM   1811 C CD2 . TYR A 1 269 ? 139.167 138.326 156.617 1.00 52.70  ? 248 TYR B CD2 1 
ATOM   1812 C CE1 . TYR A 1 269 ? 138.224 135.846 157.360 1.00 49.24  ? 248 TYR B CE1 1 
ATOM   1813 C CE2 . TYR A 1 269 ? 139.944 137.503 157.409 1.00 50.35  ? 248 TYR B CE2 1 
ATOM   1814 C CZ  . TYR A 1 269 ? 139.468 136.265 157.776 1.00 51.69  ? 248 TYR B CZ  1 
ATOM   1815 O OH  . TYR A 1 269 ? 140.237 135.441 158.563 1.00 51.99  ? 248 TYR B OH  1 
ATOM   1816 N N   . LYS A 1 270 ? 135.548 141.380 154.970 1.00 31.33  ? 249 LYS B N   1 
ATOM   1817 C CA  . LYS A 1 270 ? 134.924 142.506 154.294 1.00 30.58  ? 249 LYS B CA  1 
ATOM   1818 C C   . LYS A 1 270 ? 135.988 143.554 154.005 1.00 28.70  ? 249 LYS B C   1 
ATOM   1819 O O   . LYS A 1 270 ? 136.871 143.790 154.832 1.00 29.43  ? 249 LYS B O   1 
ATOM   1820 C CB  . LYS A 1 270 ? 133.791 143.094 155.142 1.00 29.20  ? 249 LYS B CB  1 
ATOM   1821 C CG  . LYS A 1 270 ? 133.390 144.506 154.779 1.00 36.35  ? 249 LYS B CG  1 
ATOM   1822 C CD  . LYS A 1 270 ? 132.678 145.176 155.936 1.00 40.49  ? 249 LYS B CD  1 
ATOM   1823 C CE  . LYS A 1 270 ? 132.936 146.670 155.944 1.00 43.52  ? 249 LYS B CE  1 
ATOM   1824 N NZ  . LYS A 1 270 ? 134.385 146.989 155.841 1.00 39.02  ? 249 LYS B NZ  1 
ATOM   1825 N N   . CYS A 1 271 ? 135.900 144.169 152.830 1.00 29.79  ? 250 CYS B N   1 
ATOM   1826 C CA  . CYS A 1 271 ? 136.875 145.169 152.417 1.00 26.92  ? 250 CYS B CA  1 
ATOM   1827 C C   . CYS A 1 271 ? 136.277 146.104 151.373 1.00 29.52  ? 250 CYS B C   1 
ATOM   1828 O O   . CYS A 1 271 ? 135.822 145.643 150.320 1.00 36.94  ? 250 CYS B O   1 
ATOM   1829 C CB  . CYS A 1 271 ? 138.126 144.486 151.867 1.00 24.08  ? 250 CYS B CB  1 
ATOM   1830 S SG  . CYS A 1 271 ? 139.362 145.606 151.217 1.00 32.16  ? 250 CYS B SG  1 
ATOM   1831 N N   . PRO A 1 272 ? 136.245 147.412 151.624 1.00 30.65  ? 251 PRO B N   1 
ATOM   1832 C CA  . PRO A 1 272 ? 135.788 148.343 150.585 1.00 33.27  ? 251 PRO B CA  1 
ATOM   1833 C C   . PRO A 1 272 ? 136.765 148.394 149.421 1.00 27.86  ? 251 PRO B C   1 
ATOM   1834 O O   . PRO A 1 272 ? 137.982 148.308 149.601 1.00 24.73  ? 251 PRO B O   1 
ATOM   1835 C CB  . PRO A 1 272 ? 135.712 149.687 151.317 1.00 21.60  ? 251 PRO B CB  1 
ATOM   1836 C CG  . PRO A 1 272 ? 136.648 149.546 152.455 1.00 25.84  ? 251 PRO B CG  1 
ATOM   1837 C CD  . PRO A 1 272 ? 136.615 148.107 152.867 1.00 27.97  ? 251 PRO B CD  1 
ATOM   1838 N N   . VAL A 1 273 ? 136.219 148.544 148.216 1.00 26.21  ? 252 VAL B N   1 
ATOM   1839 C CA  . VAL A 1 273 ? 137.037 148.582 147.010 1.00 24.52  ? 252 VAL B CA  1 
ATOM   1840 C C   . VAL A 1 273 ? 136.832 149.914 146.301 1.00 24.46  ? 252 VAL B C   1 
ATOM   1841 O O   . VAL A 1 273 ? 137.719 150.394 145.587 1.00 23.78  ? 252 VAL B O   1 
ATOM   1842 C CB  . VAL A 1 273 ? 136.712 147.397 146.081 1.00 18.63  ? 252 VAL B CB  1 
ATOM   1843 C CG1 . VAL A 1 273 ? 137.246 146.106 146.669 1.00 15.46  ? 252 VAL B CG1 1 
ATOM   1844 C CG2 . VAL A 1 273 ? 135.223 147.292 145.852 1.00 13.86  ? 252 VAL B CG2 1 
ATOM   1845 N N   . ALA A 1 274 ? 135.665 150.521 146.496 1.00 24.81  ? 253 ALA B N   1 
ATOM   1846 C CA  . ALA A 1 274 ? 135.347 151.814 145.912 1.00 15.14  ? 253 ALA B CA  1 
ATOM   1847 C C   . ALA A 1 274 ? 134.585 152.644 146.931 1.00 25.07  ? 253 ALA B C   1 
ATOM   1848 O O   . ALA A 1 274 ? 133.695 152.134 147.616 1.00 17.73  ? 253 ALA B O   1 
ATOM   1849 C CB  . ALA A 1 274 ? 134.525 151.668 144.629 1.00 15.14  ? 253 ALA B CB  1 
ATOM   1850 N N   . MET A 1 275 ? 134.938 153.922 147.026 1.00 37.55  ? 254 MET B N   1 
ATOM   1851 C CA  . MET A 1 275 ? 134.343 154.827 147.997 1.00 32.71  ? 254 MET B CA  1 
ATOM   1852 C C   . MET A 1 275 ? 134.116 156.182 147.349 1.00 33.42  ? 254 MET B C   1 
ATOM   1853 O O   . MET A 1 275 ? 134.931 156.636 146.542 1.00 34.26  ? 254 MET B O   1 
ATOM   1854 C CB  . MET A 1 275 ? 135.239 154.973 149.234 1.00 33.38  ? 254 MET B CB  1 
ATOM   1855 C CG  . MET A 1 275 ? 134.704 155.913 150.297 1.00 36.98  ? 254 MET B CG  1 
ATOM   1856 S SD  . MET A 1 275 ? 133.475 155.143 151.361 1.00 54.32  ? 254 MET B SD  1 
ATOM   1857 C CE  . MET A 1 275 ? 132.959 156.548 152.342 1.00 38.30  ? 254 MET B CE  1 
ATOM   1858 N N   . GLU A 1 276 ? 133.000 156.822 147.698 1.00 36.92  ? 255 GLU B N   1 
ATOM   1859 C CA  . GLU A 1 276 ? 132.688 158.152 147.178 1.00 34.36  ? 255 GLU B CA  1 
ATOM   1860 C C   . GLU A 1 276 ? 131.941 158.915 148.267 1.00 35.34  ? 255 GLU B C   1 
ATOM   1861 O O   . GLU A 1 276 ? 130.720 158.794 148.385 1.00 39.93  ? 255 GLU B O   1 
ATOM   1862 C CB  . GLU A 1 276 ? 131.869 158.068 145.899 1.00 29.05  ? 255 GLU B CB  1 
ATOM   1863 C CG  . GLU A 1 276 ? 131.716 159.395 145.188 1.00 32.06  ? 255 GLU B CG  1 
ATOM   1864 C CD  . GLU A 1 276 ? 130.282 159.694 144.823 1.00 37.39  ? 255 GLU B CD  1 
ATOM   1865 O OE1 . GLU A 1 276 ? 129.587 158.770 144.357 1.00 39.99  ? 255 GLU B OE1 1 
ATOM   1866 O OE2 . GLU A 1 276 ? 129.849 160.850 145.002 1.00 37.13  ? 255 GLU B OE2 1 
ATOM   1867 N N   . GLU A 1 277 ? 132.675 159.705 149.041 1.00 44.45  ? 256 GLU B N   1 
ATOM   1868 C CA  . GLU A 1 277 ? 132.090 160.517 150.101 1.00 43.13  ? 256 GLU B CA  1 
ATOM   1869 C C   . GLU A 1 277 ? 131.613 161.831 149.497 1.00 41.73  ? 256 GLU B C   1 
ATOM   1870 O O   . GLU A 1 277 ? 132.424 162.647 149.047 1.00 48.61  ? 256 GLU B O   1 
ATOM   1871 C CB  . GLU A 1 277 ? 133.102 160.760 151.215 1.00 42.03  ? 256 GLU B CB  1 
ATOM   1872 C CG  . GLU A 1 277 ? 132.585 161.644 152.326 1.00 39.72  ? 256 GLU B CG  1 
ATOM   1873 C CD  . GLU A 1 277 ? 132.904 161.093 153.695 1.00 48.76  ? 256 GLU B CD  1 
ATOM   1874 O OE1 . GLU A 1 277 ? 134.017 160.558 153.880 1.00 50.72  ? 256 GLU B OE1 1 
ATOM   1875 O OE2 . GLU A 1 277 ? 132.042 161.193 154.589 1.00 50.91  ? 256 GLU B OE2 1 
ATOM   1876 N N   . ALA A 1 278 ? 130.302 162.037 149.487 1.00 31.96  ? 257 ALA B N   1 
ATOM   1877 C CA  . ALA A 1 278 ? 129.704 163.249 148.952 1.00 35.40  ? 257 ALA B CA  1 
ATOM   1878 C C   . ALA A 1 278 ? 129.327 164.185 150.090 1.00 41.25  ? 257 ALA B C   1 
ATOM   1879 O O   . ALA A 1 278 ? 128.857 163.743 151.141 1.00 43.89  ? 257 ALA B O   1 
ATOM   1880 C CB  . ALA A 1 278 ? 128.470 162.927 148.110 1.00 38.11  ? 257 ALA B CB  1 
ATOM   1881 N N   . ASP A 1 279 ? 129.529 165.479 149.872 1.00 45.15  ? 258 ASP B N   1 
ATOM   1882 C CA  . ASP A 1 279 ? 129.263 166.489 150.885 1.00 47.28  ? 258 ASP B CA  1 
ATOM   1883 C C   . ASP A 1 279 ? 127.845 167.036 150.815 1.00 48.81  ? 258 ASP B C   1 
ATOM   1884 O O   . ASP A 1 279 ? 127.537 168.008 151.511 1.00 50.10  ? 258 ASP B O   1 
ATOM   1885 C CB  . ASP A 1 279 ? 130.267 167.638 150.760 1.00 44.27  ? 258 ASP B CB  1 
ATOM   1886 N N   . ASP A 1 280 ? 126.985 166.448 149.988 1.00 37.09  ? 259 ASP B N   1 
ATOM   1887 C CA  . ASP A 1 280 ? 125.619 166.934 149.867 1.00 37.55  ? 259 ASP B CA  1 
ATOM   1888 C C   . ASP A 1 280 ? 124.877 166.784 151.189 1.00 34.86  ? 259 ASP B C   1 
ATOM   1889 O O   . ASP A 1 280 ? 124.946 165.743 151.846 1.00 42.94  ? 259 ASP B O   1 
ATOM   1890 C CB  . ASP A 1 280 ? 124.888 166.179 148.759 1.00 40.35  ? 259 ASP B CB  1 
ATOM   1891 N N   . THR A 1 281 ? 124.160 167.835 151.574 1.00 36.89  ? 260 THR B N   1 
ATOM   1892 C CA  . THR A 1 281 ? 123.446 167.886 152.839 1.00 42.50  ? 260 THR B CA  1 
ATOM   1893 C C   . THR A 1 281 ? 121.956 168.061 152.587 1.00 43.52  ? 260 THR B C   1 
ATOM   1894 O O   . THR A 1 281 ? 121.546 168.710 151.621 1.00 48.15  ? 260 THR B O   1 
ATOM   1895 C CB  . THR A 1 281 ? 123.948 169.036 153.719 1.00 47.74  ? 260 THR B CB  1 
ATOM   1896 O OG1 . THR A 1 281 ? 123.597 170.286 153.113 1.00 48.84  ? 260 THR B OG1 1 
ATOM   1897 C CG2 . THR A 1 281 ? 125.459 168.969 153.882 1.00 42.32  ? 260 THR B CG2 1 
ATOM   1898 N N   . VAL A 1 282 ? 121.148 167.478 153.467 1.00 40.03  ? 261 VAL B N   1 
ATOM   1899 C CA  . VAL A 1 282 ? 119.695 167.556 153.375 1.00 41.87  ? 261 VAL B CA  1 
ATOM   1900 C C   . VAL A 1 282 ? 119.184 168.309 154.594 1.00 46.54  ? 261 VAL B C   1 
ATOM   1901 O O   . VAL A 1 282 ? 119.422 167.891 155.734 1.00 49.37  ? 261 VAL B O   1 
ATOM   1902 C CB  . VAL A 1 282 ? 119.051 166.164 153.280 1.00 42.14  ? 261 VAL B CB  1 
ATOM   1903 C CG1 . VAL A 1 282 ? 117.629 166.273 152.749 1.00 36.61  ? 261 VAL B CG1 1 
ATOM   1904 C CG2 . VAL A 1 282 ? 119.890 165.256 152.402 1.00 44.17  ? 261 VAL B CG2 1 
ATOM   1905 N N   . ALA A 1 283 ? 118.488 169.413 154.354 1.00 45.30  ? 262 ALA B N   1 
ATOM   1906 C CA  . ALA A 1 283 ? 117.906 170.205 155.422 1.00 40.19  ? 262 ALA B CA  1 
ATOM   1907 C C   . ALA A 1 283 ? 116.656 169.527 155.968 1.00 38.22  ? 262 ALA B C   1 
ATOM   1908 O O   . ALA A 1 283 ? 116.023 168.725 155.279 1.00 42.80  ? 262 ALA B O   1 
ATOM   1909 C CB  . ALA A 1 283 ? 117.569 171.601 154.911 1.00 43.24  ? 262 ALA B CB  1 
ATOM   1910 N N   . PRO A 1 284 ? 116.284 169.826 157.212 1.00 42.80  ? 263 PRO B N   1 
ATOM   1911 C CA  . PRO A 1 284 ? 115.060 169.241 157.773 1.00 46.30  ? 263 PRO B CA  1 
ATOM   1912 C C   . PRO A 1 284 ? 113.836 169.603 156.946 1.00 41.42  ? 263 PRO B C   1 
ATOM   1913 O O   . PRO A 1 284 ? 113.727 170.708 156.412 1.00 41.27  ? 263 PRO B O   1 
ATOM   1914 C CB  . PRO A 1 284 ? 114.992 169.846 159.178 1.00 43.63  ? 263 PRO B CB  1 
ATOM   1915 C CG  . PRO A 1 284 ? 116.405 170.157 159.516 1.00 44.79  ? 263 PRO B CG  1 
ATOM   1916 C CD  . PRO A 1 284 ? 117.054 170.566 158.226 1.00 43.04  ? 263 PRO B CD  1 
ATOM   1917 N N   . SER A 1 285 ? 112.911 168.647 156.846 1.00 47.80  ? 264 SER B N   1 
ATOM   1918 C CA  . SER A 1 285 ? 111.688 168.792 156.056 1.00 47.23  ? 264 SER B CA  1 
ATOM   1919 C C   . SER A 1 285 ? 112.006 169.111 154.594 1.00 47.42  ? 264 SER B C   1 
ATOM   1920 O O   . SER A 1 285 ? 111.466 170.049 154.003 1.00 47.75  ? 264 SER B O   1 
ATOM   1921 C CB  . SER A 1 285 ? 110.762 169.848 156.663 1.00 45.93  ? 264 SER B CB  1 
ATOM   1922 O OG  . SER A 1 285 ? 111.241 171.155 156.405 1.00 49.44  ? 264 SER B OG  1 
ATOM   1923 N N   . SER A 1 286 ? 112.895 168.311 154.007 1.00 38.42  ? 265 SER B N   1 
ATOM   1924 C CA  . SER A 1 286 ? 113.267 168.471 152.610 1.00 37.56  ? 265 SER B CA  1 
ATOM   1925 C C   . SER A 1 286 ? 113.719 167.128 152.057 1.00 37.00  ? 265 SER B C   1 
ATOM   1926 O O   . SER A 1 286 ? 114.109 166.228 152.803 1.00 42.56  ? 265 SER B O   1 
ATOM   1927 C CB  . SER A 1 286 ? 114.372 169.519 152.440 1.00 44.91  ? 265 SER B CB  1 
ATOM   1928 O OG  . SER A 1 286 ? 115.565 169.110 153.084 1.00 46.02  ? 265 SER B OG  1 
ATOM   1929 N N   . THR A 1 287 ? 113.670 167.007 150.734 1.00 31.65  ? 266 THR B N   1 
ATOM   1930 C CA  . THR A 1 287 ? 114.085 165.805 150.027 1.00 29.40  ? 266 THR B CA  1 
ATOM   1931 C C   . THR A 1 287 ? 115.407 166.047 149.308 1.00 34.60  ? 266 THR B C   1 
ATOM   1932 O O   . THR A 1 287 ? 115.924 167.165 149.257 1.00 41.16  ? 266 THR B O   1 
ATOM   1933 C CB  . THR A 1 287 ? 113.014 165.360 149.026 1.00 32.20  ? 266 THR B CB  1 
ATOM   1934 O OG1 . THR A 1 287 ? 113.238 166.009 147.770 1.00 41.55  ? 266 THR B OG1 1 
ATOM   1935 C CG2 . THR A 1 287 ? 111.629 165.719 149.533 1.00 34.40  ? 266 THR B CG2 1 
ATOM   1936 N N   . PHE A 1 288 ? 115.955 164.972 148.744 1.00 26.87  ? 267 PHE B N   1 
ATOM   1937 C CA  . PHE A 1 288 ? 117.240 165.045 148.055 1.00 20.15  ? 267 PHE B CA  1 
ATOM   1938 C C   . PHE A 1 288 ? 117.363 163.847 147.131 1.00 24.85  ? 267 PHE B C   1 
ATOM   1939 O O   . PHE A 1 288 ? 117.400 162.709 147.602 1.00 35.46  ? 267 PHE B O   1 
ATOM   1940 C CB  . PHE A 1 288 ? 118.392 165.072 149.055 1.00 19.96  ? 267 PHE B CB  1 
ATOM   1941 C CG  . PHE A 1 288 ? 119.735 164.800 148.444 1.00 22.45  ? 267 PHE B CG  1 
ATOM   1942 C CD1 . PHE A 1 288 ? 120.438 165.806 147.812 1.00 31.14  ? 267 PHE B CD1 1 
ATOM   1943 C CD2 . PHE A 1 288 ? 120.301 163.541 148.516 1.00 22.13  ? 267 PHE B CD2 1 
ATOM   1944 C CE1 . PHE A 1 288 ? 121.674 165.557 147.258 1.00 29.77  ? 267 PHE B CE1 1 
ATOM   1945 C CE2 . PHE A 1 288 ? 121.533 163.290 147.960 1.00 17.00  ? 267 PHE B CE2 1 
ATOM   1946 C CZ  . PHE A 1 288 ? 122.220 164.297 147.335 1.00 21.93  ? 267 PHE B CZ  1 
ATOM   1947 N N   . CYS A 1 289 ? 117.436 164.099 145.828 1.00 28.79  ? 268 CYS B N   1 
ATOM   1948 C CA  . CYS A 1 289 ? 117.604 163.057 144.826 1.00 22.77  ? 268 CYS B CA  1 
ATOM   1949 C C   . CYS A 1 289 ? 118.934 163.257 144.119 1.00 25.63  ? 268 CYS B C   1 
ATOM   1950 O O   . CYS A 1 289 ? 119.253 164.371 143.693 1.00 34.20  ? 268 CYS B O   1 
ATOM   1951 C CB  . CYS A 1 289 ? 116.461 163.073 143.809 1.00 25.98  ? 268 CYS B CB  1 
ATOM   1952 S SG  . CYS A 1 289 ? 115.047 162.046 144.252 1.00 47.51  ? 268 CYS B SG  1 
ATOM   1953 N N   . LYS A 1 290 ? 119.707 162.183 143.999 1.00 14.30  ? 269 LYS B N   1 
ATOM   1954 C CA  . LYS A 1 290 ? 120.975 162.240 143.292 1.00 16.71  ? 269 LYS B CA  1 
ATOM   1955 C C   . LYS A 1 290 ? 121.286 160.866 142.726 1.00 23.88  ? 269 LYS B C   1 
ATOM   1956 O O   . LYS A 1 290 ? 120.731 159.854 143.160 1.00 36.62  ? 269 LYS B O   1 
ATOM   1957 C CB  . LYS A 1 290 ? 122.115 162.710 144.200 1.00 21.39  ? 269 LYS B CB  1 
ATOM   1958 C CG  . LYS A 1 290 ? 123.305 163.286 143.452 1.00 23.30  ? 269 LYS B CG  1 
ATOM   1959 C CD  . LYS A 1 290 ? 123.990 164.379 144.245 1.00 25.46  ? 269 LYS B CD  1 
ATOM   1960 C CE  . LYS A 1 290 ? 125.496 164.307 144.090 1.00 28.75  ? 269 LYS B CE  1 
ATOM   1961 N NZ  . LYS A 1 290 ? 126.204 164.992 145.206 1.00 30.01  ? 269 LYS B NZ  1 
ATOM   1962 N N   . VAL A 1 291 ? 122.173 160.845 141.736 1.00 24.98  ? 270 VAL B N   1 
ATOM   1963 C CA  . VAL A 1 291 ? 122.697 159.613 141.165 1.00 16.81  ? 270 VAL B CA  1 
ATOM   1964 C C   . VAL A 1 291 ? 124.213 159.683 141.238 1.00 14.63  ? 270 VAL B C   1 
ATOM   1965 O O   . VAL A 1 291 ? 124.817 160.647 140.756 1.00 23.58  ? 270 VAL B O   1 
ATOM   1966 C CB  . VAL A 1 291 ? 122.231 159.397 139.716 1.00 18.38  ? 270 VAL B CB  1 
ATOM   1967 C CG1 . VAL A 1 291 ? 122.952 158.217 139.100 1.00 18.02  ? 270 VAL B CG1 1 
ATOM   1968 C CG2 . VAL A 1 291 ? 120.731 159.184 139.672 1.00 20.32  ? 270 VAL B CG2 1 
ATOM   1969 N N   . TYR A 1 292 ? 124.823 158.674 141.840 1.00 16.18  ? 271 TYR B N   1 
ATOM   1970 C CA  . TYR A 1 292 ? 126.264 158.601 141.983 1.00 6.43   ? 271 TYR B CA  1 
ATOM   1971 C C   . TYR A 1 292 ? 126.819 157.600 140.977 1.00 21.23  ? 271 TYR B C   1 
ATOM   1972 O O   . TYR A 1 292 ? 126.081 156.972 140.217 1.00 31.71  ? 271 TYR B O   1 
ATOM   1973 C CB  . TYR A 1 292 ? 126.633 158.239 143.423 1.00 7.51   ? 271 TYR B CB  1 
ATOM   1974 C CG  . TYR A 1 292 ? 126.059 159.201 144.443 1.00 20.98  ? 271 TYR B CG  1 
ATOM   1975 C CD1 . TYR A 1 292 ? 124.724 159.142 144.812 1.00 23.91  ? 271 TYR B CD1 1 
ATOM   1976 C CD2 . TYR A 1 292 ? 126.850 160.182 145.024 1.00 27.29  ? 271 TYR B CD2 1 
ATOM   1977 C CE1 . TYR A 1 292 ? 124.197 160.025 145.729 1.00 25.29  ? 271 TYR B CE1 1 
ATOM   1978 C CE2 . TYR A 1 292 ? 126.328 161.067 145.945 1.00 17.36  ? 271 TYR B CE2 1 
ATOM   1979 C CZ  . TYR A 1 292 ? 125.000 160.981 146.292 1.00 17.19  ? 271 TYR B CZ  1 
ATOM   1980 O OH  . TYR A 1 292 ? 124.467 161.854 147.207 1.00 27.25  ? 271 TYR B OH  1 
ATOM   1981 N N   . THR A 1 293 ? 128.141 157.460 140.960 1.00 17.81  ? 272 THR B N   1 
ATOM   1982 C CA  . THR A 1 293 ? 128.783 156.548 140.019 1.00 9.09   ? 272 THR B CA  1 
ATOM   1983 C C   . THR A 1 293 ? 130.107 156.102 140.610 1.00 5.95   ? 272 THR B C   1 
ATOM   1984 O O   . THR A 1 293 ? 130.947 156.941 140.948 1.00 16.34  ? 272 THR B O   1 
ATOM   1985 C CB  . THR A 1 293 ? 128.993 157.216 138.659 1.00 21.53  ? 272 THR B CB  1 
ATOM   1986 O OG1 . THR A 1 293 ? 127.749 157.259 137.949 1.00 21.50  ? 272 THR B OG1 1 
ATOM   1987 C CG2 . THR A 1 293 ? 130.010 156.446 137.832 1.00 9.40   ? 272 THR B CG2 1 
ATOM   1988 N N   . LEU A 1 294 ? 130.297 154.793 140.724 1.00 12.23  ? 273 LEU B N   1 
ATOM   1989 C CA  . LEU A 1 294 ? 131.515 154.220 141.269 1.00 14.07  ? 273 LEU B CA  1 
ATOM   1990 C C   . LEU A 1 294 ? 132.004 153.111 140.356 1.00 7.95   ? 273 LEU B C   1 
ATOM   1991 O O   . LEU A 1 294 ? 131.216 152.456 139.672 1.00 27.56  ? 273 LEU B O   1 
ATOM   1992 C CB  . LEU A 1 294 ? 131.296 153.662 142.677 1.00 23.12  ? 273 LEU B CB  1 
ATOM   1993 C CG  . LEU A 1 294 ? 131.244 154.680 143.810 1.00 18.17  ? 273 LEU B CG  1 
ATOM   1994 C CD1 . LEU A 1 294 ? 129.820 155.119 144.020 1.00 18.83  ? 273 LEU B CD1 1 
ATOM   1995 C CD2 . LEU A 1 294 ? 131.804 154.082 145.080 1.00 16.35  ? 273 LEU B CD2 1 
ATOM   1996 N N   . THR A 1 295 ? 133.310 152.908 140.353 1.00 10.78  ? 274 THR B N   1 
ATOM   1997 C CA  . THR A 1 295 ? 133.903 151.824 139.589 1.00 14.61  ? 274 THR B CA  1 
ATOM   1998 C C   . THR A 1 295 ? 135.035 151.196 140.389 1.00 18.47  ? 274 THR B C   1 
ATOM   1999 O O   . THR A 1 295 ? 136.063 151.844 140.618 1.00 31.19  ? 274 THR B O   1 
ATOM   2000 C CB  . THR A 1 295 ? 134.425 152.319 138.240 1.00 12.74  ? 274 THR B CB  1 
ATOM   2001 O OG1 . THR A 1 295 ? 133.442 153.153 137.617 1.00 30.67  ? 274 THR B OG1 1 
ATOM   2002 C CG2 . THR A 1 295 ? 134.722 151.149 137.334 1.00 11.69  ? 274 THR B CG2 1 
ATOM   2003 N N   . PRO A 1 296 ? 134.884 149.955 140.843 1.00 9.52   ? 275 PRO B N   1 
ATOM   2004 C CA  . PRO A 1 296 ? 136.008 149.270 141.488 1.00 4.83   ? 275 PRO B CA  1 
ATOM   2005 C C   . PRO A 1 296 ? 137.084 148.901 140.478 1.00 10.08  ? 275 PRO B C   1 
ATOM   2006 O O   . PRO A 1 296 ? 136.794 148.440 139.373 1.00 16.77  ? 275 PRO B O   1 
ATOM   2007 C CB  . PRO A 1 296 ? 135.365 148.019 142.098 1.00 8.27   ? 275 PRO B CB  1 
ATOM   2008 C CG  . PRO A 1 296 ? 133.895 148.238 142.019 1.00 6.93   ? 275 PRO B CG  1 
ATOM   2009 C CD  . PRO A 1 296 ? 133.653 149.153 140.880 1.00 6.15   ? 275 PRO B CD  1 
ATOM   2010 N N   . PHE A 1 297 ? 138.338 149.109 140.868 1.00 14.12  ? 276 PHE B N   1 
ATOM   2011 C CA  . PHE A 1 297 ? 139.469 148.693 140.054 1.00 4.48   ? 276 PHE B CA  1 
ATOM   2012 C C   . PHE A 1 297 ? 140.673 148.477 140.958 1.00 1.99   ? 276 PHE B C   1 
ATOM   2013 O O   . PHE A 1 297 ? 140.691 148.901 142.114 1.00 9.48   ? 276 PHE B O   1 
ATOM   2014 C CB  . PHE A 1 297 ? 139.781 149.701 138.937 1.00 0.92   ? 276 PHE B CB  1 
ATOM   2015 C CG  . PHE A 1 297 ? 139.978 151.108 139.412 1.00 5.79   ? 276 PHE B CG  1 
ATOM   2016 C CD1 . PHE A 1 297 ? 138.899 151.948 139.598 1.00 20.19  ? 276 PHE B CD1 1 
ATOM   2017 C CD2 . PHE A 1 297 ? 141.243 151.596 139.653 1.00 1.96   ? 276 PHE B CD2 1 
ATOM   2018 C CE1 . PHE A 1 297 ? 139.080 153.235 140.033 1.00 0.00   ? 276 PHE B CE1 1 
ATOM   2019 C CE2 . PHE A 1 297 ? 141.425 152.883 140.082 1.00 2.31   ? 276 PHE B CE2 1 
ATOM   2020 C CZ  . PHE A 1 297 ? 140.345 153.702 140.272 1.00 5.26   ? 276 PHE B CZ  1 
ATOM   2021 N N   . LEU A 1 298 ? 141.681 147.801 140.415 1.00 3.33   ? 277 LEU B N   1 
ATOM   2022 C CA  . LEU A 1 298 ? 142.815 147.350 141.208 1.00 19.80  ? 277 LEU B CA  1 
ATOM   2023 C C   . LEU A 1 298 ? 143.903 148.405 141.377 1.00 25.58  ? 277 LEU B C   1 
ATOM   2024 O O   . LEU A 1 298 ? 144.797 148.216 142.207 1.00 29.83  ? 277 LEU B O   1 
ATOM   2025 C CB  . LEU A 1 298 ? 143.408 146.087 140.575 1.00 14.74  ? 277 LEU B CB  1 
ATOM   2026 C CG  . LEU A 1 298 ? 144.447 145.300 141.376 1.00 18.94  ? 277 LEU B CG  1 
ATOM   2027 C CD1 . LEU A 1 298 ? 143.854 144.814 142.680 1.00 17.22  ? 277 LEU B CD1 1 
ATOM   2028 C CD2 . LEU A 1 298 ? 144.997 144.147 140.565 1.00 24.88  ? 277 LEU B CD2 1 
ATOM   2029 N N   . ALA A 1 299 ? 143.848 149.513 140.637 1.00 21.06  ? 278 ALA B N   1 
ATOM   2030 C CA  . ALA A 1 299 ? 144.928 150.494 140.702 1.00 11.67  ? 278 ALA B CA  1 
ATOM   2031 C C   . ALA A 1 299 ? 145.055 151.096 142.094 1.00 21.68  ? 278 ALA B C   1 
ATOM   2032 O O   . ALA A 1 299 ? 146.169 151.304 142.587 1.00 37.11  ? 278 ALA B O   1 
ATOM   2033 C CB  . ALA A 1 299 ? 144.708 151.592 139.664 1.00 12.79  ? 278 ALA B CB  1 
ATOM   2034 N N   . ASN A 1 300 ? 143.931 151.385 142.745 1.00 19.13  ? 279 ASN B N   1 
ATOM   2035 C CA  . ASN A 1 300 ? 143.938 152.021 144.054 1.00 18.41  ? 279 ASN B CA  1 
ATOM   2036 C C   . ASN A 1 300 ? 143.762 151.030 145.199 1.00 21.46  ? 279 ASN B C   1 
ATOM   2037 O O   . ASN A 1 300 ? 143.555 151.452 146.340 1.00 33.59  ? 279 ASN B O   1 
ATOM   2038 C CB  . ASN A 1 300 ? 142.854 153.097 144.118 1.00 11.90  ? 279 ASN B CB  1 
ATOM   2039 C CG  . ASN A 1 300 ? 141.478 152.546 143.869 1.00 16.24  ? 279 ASN B CG  1 
ATOM   2040 O OD1 . ASN A 1 300 ? 141.327 151.435 143.371 1.00 28.73  ? 279 ASN B OD1 1 
ATOM   2041 N ND2 . ASN A 1 300 ? 140.458 153.322 144.208 1.00 18.03  ? 279 ASN B ND2 1 
ATOM   2042 N N   . ASN A 1 301 ? 143.843 149.725 144.924 1.00 24.89  ? 280 ASN B N   1 
ATOM   2043 C CA  . ASN A 1 301 ? 143.674 148.706 145.953 1.00 16.93  ? 280 ASN B CA  1 
ATOM   2044 C C   . ASN A 1 301 ? 144.839 147.725 145.986 1.00 27.26  ? 280 ASN B C   1 
ATOM   2045 O O   . ASN A 1 301 ? 144.711 146.644 146.567 1.00 31.07  ? 280 ASN B O   1 
ATOM   2046 C CB  . ASN A 1 301 ? 142.363 147.945 145.754 1.00 12.56  ? 280 ASN B CB  1 
ATOM   2047 C CG  . ASN A 1 301 ? 141.155 148.846 145.812 1.00 16.30  ? 280 ASN B CG  1 
ATOM   2048 O OD1 . ASN A 1 301 ? 141.137 149.829 146.547 1.00 26.21  ? 280 ASN B OD1 1 
ATOM   2049 N ND2 . ASN A 1 301 ? 140.132 148.515 145.034 1.00 6.00   ? 280 ASN B ND2 1 
ATOM   2050 N N   . ARG A 1 302 ? 145.977 148.080 145.395 1.00 26.70  ? 281 ARG B N   1 
ATOM   2051 C CA  . ARG A 1 302 ? 147.129 147.188 145.336 1.00 27.36  ? 281 ARG B CA  1 
ATOM   2052 C C   . ARG A 1 302 ? 147.856 147.065 146.667 1.00 38.89  ? 281 ARG B C   1 
ATOM   2053 O O   . ARG A 1 302 ? 148.961 146.513 146.706 1.00 35.86  ? 281 ARG B O   1 
ATOM   2054 C CB  . ARG A 1 302 ? 148.106 147.662 144.260 1.00 29.13  ? 281 ARG B CB  1 
ATOM   2055 C CG  . ARG A 1 302 ? 147.735 147.231 142.859 1.00 27.95  ? 281 ARG B CG  1 
ATOM   2056 C CD  . ARG A 1 302 ? 148.481 148.040 141.817 1.00 36.27  ? 281 ARG B CD  1 
ATOM   2057 N NE  . ARG A 1 302 ? 148.196 147.584 140.463 1.00 27.02  ? 281 ARG B NE  1 
ATOM   2058 C CZ  . ARG A 1 302 ? 148.645 146.449 139.945 1.00 36.13  ? 281 ARG B CZ  1 
ATOM   2059 N NH1 . ARG A 1 302 ? 149.410 145.626 140.641 1.00 38.39  ? 281 ARG B NH1 1 
ATOM   2060 N NH2 . ARG A 1 302 ? 148.324 146.136 138.694 1.00 37.29  ? 281 ARG B NH2 1 
ATOM   2061 N N   . GLU A 1 303 ? 147.270 147.572 147.747 1.00 51.01  ? 282 GLU B N   1 
ATOM   2062 C CA  . GLU A 1 303 ? 147.880 147.533 149.064 1.00 46.06  ? 282 GLU B CA  1 
ATOM   2063 C C   . GLU A 1 303 ? 146.993 146.925 150.140 1.00 47.26  ? 282 GLU B C   1 
ATOM   2064 O O   . GLU A 1 303 ? 147.462 146.743 151.268 1.00 48.50  ? 282 GLU B O   1 
ATOM   2065 C CB  . GLU A 1 303 ? 148.310 148.946 149.487 1.00 41.35  ? 282 GLU B CB  1 
ATOM   2066 C CG  . GLU A 1 303 ? 149.441 149.528 148.654 1.00 43.84  ? 282 GLU B CG  1 
ATOM   2067 C CD  . GLU A 1 303 ? 149.792 150.941 149.046 1.00 48.27  ? 282 GLU B CD  1 
ATOM   2068 O OE1 . GLU A 1 303 ? 149.044 151.552 149.835 1.00 47.96  ? 282 GLU B OE1 1 
ATOM   2069 O OE2 . GLU A 1 303 ? 150.822 151.443 148.561 1.00 51.75  ? 282 GLU B OE2 1 
ATOM   2070 N N   . LYS A 1 304 ? 145.737 146.609 149.835 1.00 44.02  ? 283 LYS B N   1 
ATOM   2071 C CA  . LYS A 1 304 ? 144.843 145.962 150.791 1.00 41.60  ? 283 LYS B CA  1 
ATOM   2072 C C   . LYS A 1 304 ? 145.189 144.481 150.853 1.00 44.24  ? 283 LYS B C   1 
ATOM   2073 O O   . LYS A 1 304 ? 144.850 143.713 149.951 1.00 46.81  ? 283 LYS B O   1 
ATOM   2074 C CB  . LYS A 1 304 ? 143.388 146.179 150.395 1.00 35.82  ? 283 LYS B CB  1 
ATOM   2075 C CG  . LYS A 1 304 ? 142.943 147.626 150.466 1.00 37.86  ? 283 LYS B CG  1 
ATOM   2076 C CD  . LYS A 1 304 ? 141.620 147.830 149.765 1.00 41.14  ? 283 LYS B CD  1 
ATOM   2077 C CE  . LYS A 1 304 ? 141.137 149.261 149.892 1.00 43.64  ? 283 LYS B CE  1 
ATOM   2078 N NZ  . LYS A 1 304 ? 140.735 149.585 151.285 1.00 45.29  ? 283 LYS B NZ  1 
ATOM   2079 N N   . ARG A 1 305 ? 145.871 144.078 151.920 1.00 53.91  ? 284 ARG B N   1 
ATOM   2080 C CA  . ARG A 1 305 ? 146.241 142.680 152.094 1.00 50.08  ? 284 ARG B CA  1 
ATOM   2081 C C   . ARG A 1 305 ? 145.002 141.823 152.317 1.00 47.92  ? 284 ARG B C   1 
ATOM   2082 O O   . ARG A 1 305 ? 144.071 142.217 153.023 1.00 51.14  ? 284 ARG B O   1 
ATOM   2083 C CB  . ARG A 1 305 ? 147.210 142.535 153.267 1.00 53.02  ? 284 ARG B CB  1 
ATOM   2084 C CG  . ARG A 1 305 ? 146.971 141.323 154.155 1.00 53.95  ? 284 ARG B CG  1 
ATOM   2085 C CD  . ARG A 1 305 ? 147.743 141.442 155.458 1.00 55.70  ? 284 ARG B CD  1 
ATOM   2086 N NE  . ARG A 1 305 ? 147.577 140.271 156.310 1.00 55.00  ? 284 ARG B NE  1 
ATOM   2087 C CZ  . ARG A 1 305 ? 148.490 139.320 156.458 1.00 59.02  ? 284 ARG B CZ  1 
ATOM   2088 N NH1 . ARG A 1 305 ? 149.644 139.365 155.813 1.00 59.00  ? 284 ARG B NH1 1 
ATOM   2089 N NH2 . ARG A 1 305 ? 148.239 138.301 157.274 1.00 56.71  ? 284 ARG B NH2 1 
ATOM   2090 N N   . GLY A 1 306 ? 144.992 140.643 151.702 1.00 34.61  ? 285 GLY B N   1 
ATOM   2091 C CA  . GLY A 1 306 ? 143.868 139.741 151.800 1.00 31.03  ? 285 GLY B CA  1 
ATOM   2092 C C   . GLY A 1 306 ? 142.756 140.002 150.813 1.00 29.61  ? 285 GLY B C   1 
ATOM   2093 O O   . GLY A 1 306 ? 141.765 139.263 150.815 1.00 34.42  ? 285 GLY B O   1 
ATOM   2094 N N   . LEU A 1 307 ? 142.883 141.029 149.978 1.00 32.74  ? 286 LEU B N   1 
ATOM   2095 C CA  . LEU A 1 307 ? 141.876 141.300 148.963 1.00 27.27  ? 286 LEU B CA  1 
ATOM   2096 C C   . LEU A 1 307 ? 141.788 140.134 147.991 1.00 29.51  ? 286 LEU B C   1 
ATOM   2097 O O   . LEU A 1 307 ? 142.806 139.645 147.495 1.00 31.91  ? 286 LEU B O   1 
ATOM   2098 C CB  . LEU A 1 307 ? 142.221 142.589 148.219 1.00 19.78  ? 286 LEU B CB  1 
ATOM   2099 C CG  . LEU A 1 307 ? 141.197 143.141 147.230 1.00 21.86  ? 286 LEU B CG  1 
ATOM   2100 C CD1 . LEU A 1 307 ? 139.869 143.403 147.913 1.00 28.12  ? 286 LEU B CD1 1 
ATOM   2101 C CD2 . LEU A 1 307 ? 141.728 144.403 146.591 1.00 17.07  ? 286 LEU B CD2 1 
ATOM   2102 N N   . ALA A 1 308 ? 140.565 139.689 147.719 1.00 25.14  ? 287 ALA B N   1 
ATOM   2103 C CA  . ALA A 1 308 ? 140.349 138.553 146.837 1.00 5.47   ? 287 ALA B CA  1 
ATOM   2104 C C   . ALA A 1 308 ? 140.519 138.994 145.392 1.00 23.17  ? 287 ALA B C   1 
ATOM   2105 O O   . ALA A 1 308 ? 139.764 139.838 144.899 1.00 31.48  ? 287 ALA B O   1 
ATOM   2106 C CB  . ALA A 1 308 ? 138.962 137.956 147.059 1.00 14.96  ? 287 ALA B CB  1 
ATOM   2107 N N   . LEU A 1 309 ? 141.517 138.432 144.724 1.00 22.25  ? 288 LEU B N   1 
ATOM   2108 C CA  . LEU A 1 309 ? 141.743 138.629 143.304 1.00 8.96   ? 288 LEU B CA  1 
ATOM   2109 C C   . LEU A 1 309 ? 141.339 137.369 142.555 1.00 16.15  ? 288 LEU B C   1 
ATOM   2110 O O   . LEU A 1 309 ? 141.066 136.325 143.148 1.00 28.42  ? 288 LEU B O   1 
ATOM   2111 C CB  . LEU A 1 309 ? 143.209 138.972 143.029 1.00 9.54   ? 288 LEU B CB  1 
ATOM   2112 C CG  . LEU A 1 309 ? 143.755 140.219 143.722 1.00 4.94   ? 288 LEU B CG  1 
ATOM   2113 C CD1 . LEU A 1 309 ? 145.166 140.488 143.269 1.00 16.08  ? 288 LEU B CD1 1 
ATOM   2114 C CD2 . LEU A 1 309 ? 142.873 141.411 143.442 1.00 10.98  ? 288 LEU B CD2 1 
ATOM   2115 N N   . ASP A 1 310 ? 141.282 137.478 141.236 1.00 17.36  ? 289 ASP B N   1 
ATOM   2116 C CA  . ASP A 1 310 ? 140.987 136.303 140.438 1.00 5.00   ? 289 ASP B CA  1 
ATOM   2117 C C   . ASP A 1 310 ? 142.203 135.385 140.400 1.00 14.94  ? 289 ASP B C   1 
ATOM   2118 O O   . ASP A 1 310 ? 143.337 135.805 140.635 1.00 27.45  ? 289 ASP B O   1 
ATOM   2119 C CB  . ASP A 1 310 ? 140.567 136.703 139.028 1.00 10.95  ? 289 ASP B CB  1 
ATOM   2120 C CG  . ASP A 1 310 ? 139.101 136.459 138.775 1.00 21.81  ? 289 ASP B CG  1 
ATOM   2121 O OD1 . ASP A 1 310 ? 138.417 135.959 139.689 1.00 23.33  ? 289 ASP B OD1 1 
ATOM   2122 O OD2 . ASP A 1 310 ? 138.628 136.764 137.664 1.00 26.07  ? 289 ASP B OD2 1 
ATOM   2123 N N   . GLY A 1 311 ? 141.951 134.112 140.113 1.00 7.90   ? 290 GLY B N   1 
ATOM   2124 C CA  . GLY A 1 311 ? 143.002 133.116 140.108 1.00 2.18   ? 290 GLY B CA  1 
ATOM   2125 C C   . GLY A 1 311 ? 144.134 133.436 139.158 1.00 15.32  ? 290 GLY B C   1 
ATOM   2126 O O   . GLY A 1 311 ? 143.902 133.768 137.994 1.00 28.11  ? 290 GLY B O   1 
ATOM   2127 N N   . LYS A 1 312 ? 145.363 133.346 139.646 1.00 22.70  ? 291 LYS B N   1 
ATOM   2128 C CA  . LYS A 1 312 ? 146.545 133.599 138.842 1.00 19.32  ? 291 LYS B CA  1 
ATOM   2129 C C   . LYS A 1 312 ? 147.151 132.285 138.372 1.00 17.68  ? 291 LYS B C   1 
ATOM   2130 O O   . LYS A 1 312 ? 146.996 131.245 139.014 1.00 23.31  ? 291 LYS B O   1 
ATOM   2131 C CB  . LYS A 1 312 ? 147.586 134.390 139.635 1.00 17.42  ? 291 LYS B CB  1 
ATOM   2132 C CG  . LYS A 1 312 ? 147.142 135.780 140.037 1.00 11.72  ? 291 LYS B CG  1 
ATOM   2133 C CD  . LYS A 1 312 ? 148.209 136.481 140.853 1.00 25.51  ? 291 LYS B CD  1 
ATOM   2134 C CE  . LYS A 1 312 ? 147.785 137.888 141.218 1.00 25.32  ? 291 LYS B CE  1 
ATOM   2135 N NZ  . LYS A 1 312 ? 146.369 138.148 140.853 1.00 25.11  ? 291 LYS B NZ  1 
ATOM   2136 N N   . LEU A 1 313 ? 147.848 132.341 137.237 1.00 20.55  ? 292 LEU B N   1 
ATOM   2137 C CA  . LEU A 1 313 ? 148.591 131.170 136.775 1.00 22.44  ? 292 LEU B CA  1 
ATOM   2138 C C   . LEU A 1 313 ? 149.925 131.071 137.508 1.00 29.56  ? 292 LEU B C   1 
ATOM   2139 O O   . LEU A 1 313 ? 150.174 130.104 138.234 1.00 31.95  ? 292 LEU B O   1 
ATOM   2140 C CB  . LEU A 1 313 ? 148.789 131.230 135.258 1.00 26.70  ? 292 LEU B CB  1 
ATOM   2141 C CG  . LEU A 1 313 ? 147.608 130.742 134.417 1.00 24.38  ? 292 LEU B CG  1 
ATOM   2142 C CD1 . LEU A 1 313 ? 147.943 130.790 132.939 1.00 26.80  ? 292 LEU B CD1 1 
ATOM   2143 C CD2 . LEU A 1 313 ? 147.188 129.343 134.828 1.00 10.95  ? 292 LEU B CD2 1 
ATOM   2144 N N   . LYS A 1 314 ? 150.801 132.061 137.331 1.00 37.96  ? 293 LYS B N   1 
ATOM   2145 C CA  . LYS A 1 314 ? 152.002 132.143 138.154 1.00 42.92  ? 293 LYS B CA  1 
ATOM   2146 C C   . LYS A 1 314 ? 152.058 133.416 138.986 1.00 42.94  ? 293 LYS B C   1 
ATOM   2147 O O   . LYS A 1 314 ? 151.992 133.343 140.217 1.00 45.96  ? 293 LYS B O   1 
ATOM   2148 C CB  . LYS A 1 314 ? 153.245 132.037 137.260 1.00 43.44  ? 293 LYS B CB  1 
ATOM   2149 C CG  . LYS A 1 314 ? 153.252 130.826 136.345 1.00 42.94  ? 293 LYS B CG  1 
ATOM   2150 C CD  . LYS A 1 314 ? 154.085 131.071 135.099 1.00 45.92  ? 293 LYS B CD  1 
ATOM   2151 C CE  . LYS A 1 314 ? 155.572 131.061 135.410 1.00 48.74  ? 293 LYS B CE  1 
ATOM   2152 N NZ  . LYS A 1 314 ? 156.274 132.211 134.774 1.00 45.83  ? 293 LYS B NZ  1 
ATOM   2153 N N   . HIS A 1 315 ? 152.155 134.584 138.356 1.00 48.95  ? 294 HIS B N   1 
ATOM   2154 C CA  . HIS A 1 315 ? 152.240 135.832 139.105 1.00 46.41  ? 294 HIS B CA  1 
ATOM   2155 C C   . HIS A 1 315 ? 151.565 137.011 138.423 1.00 46.55  ? 294 HIS B C   1 
ATOM   2156 O O   . HIS A 1 315 ? 151.647 138.122 138.951 1.00 43.86  ? 294 HIS B O   1 
ATOM   2157 C CB  . HIS A 1 315 ? 153.712 136.171 139.386 1.00 42.54  ? 294 HIS B CB  1 
ATOM   2158 C CG  . HIS A 1 315 ? 154.299 135.403 140.529 1.00 52.55  ? 294 HIS B CG  1 
ATOM   2159 N ND1 . HIS A 1 315 ? 153.642 135.236 141.729 1.00 51.00  ? 294 HIS B ND1 1 
ATOM   2160 C CD2 . HIS A 1 315 ? 155.479 134.750 140.653 1.00 52.05  ? 294 HIS B CD2 1 
ATOM   2161 C CE1 . HIS A 1 315 ? 154.393 134.517 142.544 1.00 48.08  ? 294 HIS B CE1 1 
ATOM   2162 N NE2 . HIS A 1 315 ? 155.513 134.209 141.915 1.00 50.23  ? 294 HIS B NE2 1 
ATOM   2163 N N   . GLU A 1 316 ? 150.911 136.822 137.281 1.00 38.97  ? 295 GLU B N   1 
ATOM   2164 C CA  . GLU A 1 316 ? 150.413 137.937 136.494 1.00 28.32  ? 295 GLU B CA  1 
ATOM   2165 C C   . GLU A 1 316 ? 149.261 138.637 137.212 1.00 32.19  ? 295 GLU B C   1 
ATOM   2166 O O   . GLU A 1 316 ? 148.637 138.096 138.126 1.00 41.29  ? 295 GLU B O   1 
ATOM   2167 C CB  . GLU A 1 316 ? 149.971 137.455 135.114 1.00 32.35  ? 295 GLU B CB  1 
ATOM   2168 C CG  . GLU A 1 316 ? 148.546 136.925 135.062 1.00 37.75  ? 295 GLU B CG  1 
ATOM   2169 C CD  . GLU A 1 316 ? 148.392 135.561 135.715 1.00 35.88  ? 295 GLU B CD  1 
ATOM   2170 O OE1 . GLU A 1 316 ? 149.415 134.903 135.989 1.00 38.47  ? 295 GLU B OE1 1 
ATOM   2171 O OE2 . GLU A 1 316 ? 147.240 135.148 135.953 1.00 40.03  ? 295 GLU B OE2 1 
ATOM   2172 N N   . ASP A 1 317 ? 148.986 139.865 136.787 1.00 30.61  ? 296 ASP B N   1 
ATOM   2173 C CA  . ASP A 1 317 ? 147.915 140.652 137.380 1.00 25.07  ? 296 ASP B CA  1 
ATOM   2174 C C   . ASP A 1 317 ? 146.558 140.132 136.934 1.00 22.96  ? 296 ASP B C   1 
ATOM   2175 O O   . ASP A 1 317 ? 146.325 139.916 135.742 1.00 34.19  ? 296 ASP B O   1 
ATOM   2176 C CB  . ASP A 1 317 ? 148.055 142.125 137.001 1.00 24.53  ? 296 ASP B CB  1 
ATOM   2177 C CG  . ASP A 1 317 ? 148.829 142.920 138.028 1.00 34.53  ? 296 ASP B CG  1 
ATOM   2178 O OD1 . ASP A 1 317 ? 148.450 142.884 139.216 1.00 42.58  ? 296 ASP B OD1 1 
ATOM   2179 O OD2 . ASP A 1 317 ? 149.811 143.588 137.649 1.00 32.84  ? 296 ASP B OD2 1 
ATOM   2180 N N   . THR A 1 318 ? 145.664 139.939 137.896 1.00 16.27  ? 297 THR B N   1 
ATOM   2181 C CA  . THR A 1 318 ? 144.277 139.601 137.634 1.00 15.39  ? 297 THR B CA  1 
ATOM   2182 C C   . THR A 1 318 ? 143.387 140.632 138.309 1.00 12.30  ? 297 THR B C   1 
ATOM   2183 O O   . THR A 1 318 ? 143.779 141.264 139.292 1.00 16.51  ? 297 THR B O   1 
ATOM   2184 C CB  . THR A 1 318 ? 143.925 138.196 138.140 1.00 16.87  ? 297 THR B CB  1 
ATOM   2185 O OG1 . THR A 1 318 ? 144.515 137.986 139.428 1.00 24.20  ? 297 THR B OG1 1 
ATOM   2186 C CG2 . THR A 1 318 ? 144.436 137.140 137.181 1.00 20.38  ? 297 THR B CG2 1 
ATOM   2187 N N   . ASN A 1 319 ? 142.185 140.797 137.773 1.00 10.98  ? 298 ASN B N   1 
ATOM   2188 C CA  . ASN A 1 319 ? 141.258 141.784 138.294 1.00 8.75   ? 298 ASN B CA  1 
ATOM   2189 C C   . ASN A 1 319 ? 140.780 141.379 139.685 1.00 20.06  ? 298 ASN B C   1 
ATOM   2190 O O   . ASN A 1 319 ? 141.187 140.359 140.246 1.00 28.21  ? 298 ASN B O   1 
ATOM   2191 C CB  . ASN A 1 319 ? 140.077 141.945 137.343 1.00 0.00   ? 298 ASN B CB  1 
ATOM   2192 C CG  . ASN A 1 319 ? 139.529 140.618 136.872 1.00 7.57   ? 298 ASN B CG  1 
ATOM   2193 O OD1 . ASN A 1 319 ? 139.966 140.081 135.858 1.00 18.09  ? 298 ASN B OD1 1 
ATOM   2194 N ND2 . ASN A 1 319 ? 138.568 140.080 137.608 1.00 0.69   ? 298 ASN B ND2 1 
ATOM   2195 N N   . LEU A 1 320 ? 139.905 142.203 140.252 1.00 14.83  ? 299 LEU B N   1 
ATOM   2196 C CA  . LEU A 1 320 ? 139.237 141.833 141.488 1.00 7.53   ? 299 LEU B CA  1 
ATOM   2197 C C   . LEU A 1 320 ? 138.433 140.560 141.271 1.00 10.90  ? 299 LEU B C   1 
ATOM   2198 O O   . LEU A 1 320 ? 137.888 140.332 140.190 1.00 28.20  ? 299 LEU B O   1 
ATOM   2199 C CB  . LEU A 1 320 ? 138.324 142.963 141.959 1.00 9.21   ? 299 LEU B CB  1 
ATOM   2200 C CG  . LEU A 1 320 ? 138.956 144.323 142.252 1.00 7.33   ? 299 LEU B CG  1 
ATOM   2201 C CD1 . LEU A 1 320 ? 137.881 145.346 142.551 1.00 1.82   ? 299 LEU B CD1 1 
ATOM   2202 C CD2 . LEU A 1 320 ? 139.926 144.225 143.404 1.00 17.24  ? 299 LEU B CD2 1 
ATOM   2203 N N   . ALA A 1 321 ? 138.374 139.724 142.301 1.00 17.00  ? 300 ALA B N   1 
ATOM   2204 C CA  . ALA A 1 321 ? 137.741 138.421 142.170 1.00 4.66   ? 300 ALA B CA  1 
ATOM   2205 C C   . ALA A 1 321 ? 136.281 138.567 141.773 1.00 10.45  ? 300 ALA B C   1 
ATOM   2206 O O   . ALA A 1 321 ? 135.590 139.489 142.208 1.00 25.30  ? 300 ALA B O   1 
ATOM   2207 C CB  . ALA A 1 321 ? 137.854 137.644 143.478 1.00 16.69  ? 300 ALA B CB  1 
ATOM   2208 N N   . SER A 1 322 ? 135.821 137.660 140.922 1.00 8.35   ? 301 SER B N   1 
ATOM   2209 C CA  . SER A 1 322 ? 134.433 137.660 140.501 1.00 4.69   ? 301 SER B CA  1 
ATOM   2210 C C   . SER A 1 322 ? 133.541 137.097 141.600 1.00 9.23   ? 301 SER B C   1 
ATOM   2211 O O   . SER A 1 322 ? 133.991 136.392 142.506 1.00 14.17  ? 301 SER B O   1 
ATOM   2212 C CB  . SER A 1 322 ? 134.264 136.852 139.217 1.00 9.33   ? 301 SER B CB  1 
ATOM   2213 O OG  . SER A 1 322 ? 135.236 137.217 138.256 1.00 5.43   ? 301 SER B OG  1 
ATOM   2214 N N   . SER A 1 323 ? 132.256 137.423 141.512 1.00 2.33   ? 302 SER B N   1 
ATOM   2215 C CA  . SER A 1 323 ? 131.290 136.898 142.463 1.00 0.00   ? 302 SER B CA  1 
ATOM   2216 C C   . SER A 1 323 ? 131.230 135.380 142.364 1.00 9.68   ? 302 SER B C   1 
ATOM   2217 O O   . SER A 1 323 ? 131.373 134.804 141.285 1.00 19.67  ? 302 SER B O   1 
ATOM   2218 C CB  . SER A 1 323 ? 129.912 137.499 142.197 1.00 0.00   ? 302 SER B CB  1 
ATOM   2219 O OG  . SER A 1 323 ? 129.782 138.761 142.821 1.00 11.22  ? 302 SER B OG  1 
ATOM   2220 N N   . THR A 1 324 ? 131.036 134.724 143.502 1.00 17.68  ? 303 THR B N   1 
ATOM   2221 C CA  . THR A 1 324 ? 130.933 133.272 143.538 1.00 8.60   ? 303 THR B CA  1 
ATOM   2222 C C   . THR A 1 324 ? 129.477 132.889 143.313 1.00 17.40  ? 303 THR B C   1 
ATOM   2223 O O   . THR A 1 324 ? 128.610 133.207 144.130 1.00 32.52  ? 303 THR B O   1 
ATOM   2224 C CB  . THR A 1 324 ? 131.451 132.717 144.860 1.00 15.70  ? 303 THR B CB  1 
ATOM   2225 O OG1 . THR A 1 324 ? 132.878 132.814 144.885 1.00 23.01  ? 303 THR B OG1 1 
ATOM   2226 C CG2 . THR A 1 324 ? 131.055 131.263 145.008 1.00 22.73  ? 303 THR B CG2 1 
ATOM   2227 N N   . LEU A 1 325 ? 129.210 132.216 142.199 1.00 20.63  ? 304 LEU B N   1 
ATOM   2228 C CA  . LEU A 1 325 ? 127.859 131.785 141.849 1.00 24.34  ? 304 LEU B CA  1 
ATOM   2229 C C   . LEU A 1 325 ? 127.621 130.428 142.496 1.00 27.79  ? 304 LEU B C   1 
ATOM   2230 O O   . LEU A 1 325 ? 127.983 129.384 141.954 1.00 32.71  ? 304 LEU B O   1 
ATOM   2231 C CB  . LEU A 1 325 ? 127.689 131.726 140.337 1.00 24.98  ? 304 LEU B CB  1 
ATOM   2232 C CG  . LEU A 1 325 ? 127.192 132.985 139.629 1.00 28.87  ? 304 LEU B CG  1 
ATOM   2233 C CD1 . LEU A 1 325 ? 126.736 132.647 138.222 1.00 29.14  ? 304 LEU B CD1 1 
ATOM   2234 C CD2 . LEU A 1 325 ? 126.067 133.637 140.413 1.00 25.23  ? 304 LEU B CD2 1 
ATOM   2235 N N   . LEU A 1 326 ? 127.006 130.444 143.675 1.00 41.21  ? 305 LEU B N   1 
ATOM   2236 C CA  . LEU A 1 326 ? 126.752 129.208 144.401 1.00 43.74  ? 305 LEU B CA  1 
ATOM   2237 C C   . LEU A 1 326 ? 125.695 128.377 143.688 1.00 45.46  ? 305 LEU B C   1 
ATOM   2238 O O   . LEU A 1 326 ? 124.704 128.905 143.177 1.00 42.49  ? 305 LEU B O   1 
ATOM   2239 C CB  . LEU A 1 326 ? 126.308 129.510 145.830 1.00 39.85  ? 305 LEU B CB  1 
ATOM   2240 C CG  . LEU A 1 326 ? 127.292 130.321 146.667 1.00 39.73  ? 305 LEU B CG  1 
ATOM   2241 C CD1 . LEU A 1 326 ? 126.896 131.787 146.671 1.00 36.49  ? 305 LEU B CD1 1 
ATOM   2242 C CD2 . LEU A 1 326 ? 127.366 129.777 148.079 1.00 44.26  ? 305 LEU B CD2 1 
ATOM   2243 N N   . ARG A 1 327 ? 125.910 127.064 143.665 1.00 67.12  ? 306 ARG B N   1 
ATOM   2244 C CA  . ARG A 1 327 ? 125.024 126.167 142.938 1.00 65.60  ? 306 ARG B CA  1 
ATOM   2245 C C   . ARG A 1 327 ? 123.715 125.975 143.693 1.00 63.39  ? 306 ARG B C   1 
ATOM   2246 O O   . ARG A 1 327 ? 123.714 125.646 144.884 1.00 63.44  ? 306 ARG B O   1 
ATOM   2247 C CB  . ARG A 1 327 ? 125.708 124.820 142.713 1.00 63.75  ? 306 ARG B CB  1 
ATOM   2248 N N   . GLU A 1 328 ? 122.600 126.188 142.993 1.00 71.06  ? 307 GLU B N   1 
ATOM   2249 C CA  . GLU A 1 328 ? 121.250 125.983 143.516 1.00 73.05  ? 307 GLU B CA  1 
ATOM   2250 C C   . GLU A 1 328 ? 120.958 126.832 144.750 1.00 75.03  ? 307 GLU B C   1 
ATOM   2251 O O   . GLU A 1 328 ? 120.004 126.556 145.483 1.00 75.57  ? 307 GLU B O   1 
ATOM   2252 C CB  . GLU A 1 328 ? 120.993 124.503 143.826 1.00 73.62  ? 307 GLU B CB  1 
ATOM   2253 N N   . GLY A 1 329 ? 121.759 127.865 144.997 1.00 79.48  ? 308 GLY B N   1 
ATOM   2254 C CA  . GLY A 1 329 ? 121.537 128.730 146.139 1.00 79.88  ? 308 GLY B CA  1 
ATOM   2255 C C   . GLY A 1 329 ? 121.983 128.125 147.454 1.00 79.23  ? 308 GLY B C   1 
ATOM   2256 O O   . GLY A 1 329 ? 122.772 128.729 148.187 1.00 78.58  ? 308 GLY B O   1 
ATOM   2257 N N   . ALA A 1 330 ? 121.478 126.932 147.769 1.00 82.71  ? 309 ALA B N   1 
ATOM   2258 C CA  . ALA A 1 330 ? 121.814 126.236 149.014 1.00 84.62  ? 309 ALA B CA  1 
ATOM   2259 C C   . ALA A 1 330 ? 122.007 124.758 148.683 1.00 85.83  ? 309 ALA B C   1 
ATOM   2260 O O   . ALA A 1 330 ? 121.045 123.986 148.656 1.00 85.94  ? 309 ALA B O   1 
ATOM   2261 C CB  . ALA A 1 330 ? 120.738 126.442 150.072 1.00 84.96  ? 309 ALA B CB  1 
ATOM   2262 N N   . ASN A 1 331 ? 123.257 124.371 148.427 1.00 90.87  ? 310 ASN B N   1 
ATOM   2263 C CA  . ASN A 1 331 ? 123.604 122.980 148.169 1.00 90.42  ? 310 ASN B CA  1 
ATOM   2264 C C   . ASN A 1 331 ? 124.484 122.403 149.270 1.00 91.03  ? 310 ASN B C   1 
ATOM   2265 O O   . ASN A 1 331 ? 124.120 121.400 149.891 1.00 90.51  ? 310 ASN B O   1 
ATOM   2266 C CB  . ASN A 1 331 ? 124.299 122.855 146.806 1.00 86.01  ? 310 ASN B CB  1 
ATOM   2267 N N   . ARG A 1 332 ? 125.631 123.024 149.539 1.00 83.30  ? 311 ARG B N   1 
ATOM   2268 C CA  . ARG A 1 332 ? 126.532 122.585 150.595 1.00 83.12  ? 311 ARG B CA  1 
ATOM   2269 C C   . ARG A 1 332 ? 127.581 123.661 150.818 1.00 82.26  ? 311 ARG B C   1 
ATOM   2270 O O   . ARG A 1 332 ? 128.146 124.186 149.856 1.00 83.31  ? 311 ARG B O   1 
ATOM   2271 C CB  . ARG A 1 332 ? 127.209 121.254 150.239 1.00 82.58  ? 311 ARG B CB  1 
ATOM   2272 N N   . GLU A 1 333 ? 127.838 123.982 152.086 1.00 76.25  ? 312 GLU B N   1 
ATOM   2273 C CA  . GLU A 1 333 ? 128.856 124.968 152.446 1.00 74.35  ? 312 GLU B CA  1 
ATOM   2274 C C   . GLU A 1 333 ? 130.121 124.223 152.864 1.00 77.86  ? 312 GLU B C   1 
ATOM   2275 O O   . GLU A 1 333 ? 130.447 124.094 154.044 1.00 78.68  ? 312 GLU B O   1 
ATOM   2276 C CB  . GLU A 1 333 ? 128.344 125.897 153.544 1.00 70.21  ? 312 GLU B CB  1 
ATOM   2277 C CG  . GLU A 1 333 ? 129.349 126.944 154.009 1.00 69.13  ? 312 GLU B CG  1 
ATOM   2278 C CD  . GLU A 1 333 ? 129.334 128.195 153.158 1.00 73.56  ? 312 GLU B CD  1 
ATOM   2279 O OE1 . GLU A 1 333 ? 128.749 128.163 152.056 1.00 74.70  ? 312 GLU B OE1 1 
ATOM   2280 O OE2 . GLU A 1 333 ? 129.909 129.214 153.595 1.00 74.95  ? 312 GLU B OE2 1 
ATOM   2281 N N   . ILE A 1 334 ? 130.831 123.701 151.867 1.00 63.90  ? 313 ILE B N   1 
ATOM   2282 C CA  . ILE A 1 334 ? 132.148 123.121 152.099 1.00 61.33  ? 313 ILE B CA  1 
ATOM   2283 C C   . ILE A 1 334 ? 133.173 124.240 151.993 1.00 62.11  ? 313 ILE B C   1 
ATOM   2284 O O   . ILE A 1 334 ? 132.843 125.361 151.589 1.00 57.68  ? 313 ILE B O   1 
ATOM   2285 C CB  . ILE A 1 334 ? 132.468 121.971 151.127 1.00 60.67  ? 313 ILE B CB  1 
ATOM   2286 C CG1 . ILE A 1 334 ? 132.709 122.495 149.713 1.00 60.13  ? 313 ILE B CG1 1 
ATOM   2287 C CG2 . ILE A 1 334 ? 131.342 120.946 151.130 1.00 58.72  ? 313 ILE B CG2 1 
ATOM   2288 C CD1 . ILE A 1 334 ? 133.342 121.466 148.807 1.00 53.52  ? 313 ILE B CD1 1 
ATOM   2289 N N   . LEU A 1 335 ? 134.414 123.948 152.374 1.00 61.23  ? 314 LEU B N   1 
ATOM   2290 C CA  . LEU A 1 335 ? 135.465 124.950 152.432 1.00 59.10  ? 314 LEU B CA  1 
ATOM   2291 C C   . LEU A 1 335 ? 135.654 125.641 151.078 1.00 52.72  ? 314 LEU B C   1 
ATOM   2292 O O   . LEU A 1 335 ? 135.208 125.168 150.031 1.00 46.53  ? 314 LEU B O   1 
ATOM   2293 C CB  . LEU A 1 335 ? 136.776 124.310 152.885 1.00 57.39  ? 314 LEU B CB  1 
ATOM   2294 N N   . GLY A 1 336 ? 136.337 126.779 151.122 1.00 38.69  ? 315 GLY B N   1 
ATOM   2295 C CA  . GLY A 1 336 ? 136.575 127.622 149.973 1.00 35.89  ? 315 GLY B CA  1 
ATOM   2296 C C   . GLY A 1 336 ? 136.333 129.077 150.303 1.00 39.94  ? 315 GLY B C   1 
ATOM   2297 O O   . GLY A 1 336 ? 135.955 129.439 151.415 1.00 49.68  ? 315 GLY B O   1 
ATOM   2298 N N   . ILE A 1 337 ? 136.560 129.926 149.304 1.00 24.04  ? 316 ILE B N   1 
ATOM   2299 C CA  . ILE A 1 337 ? 136.349 131.364 149.426 1.00 8.88   ? 316 ILE B CA  1 
ATOM   2300 C C   . ILE A 1 337 ? 135.145 131.743 148.578 1.00 12.70  ? 316 ILE B C   1 
ATOM   2301 O O   . ILE A 1 337 ? 135.128 131.499 147.366 1.00 28.13  ? 316 ILE B O   1 
ATOM   2302 C CB  . ILE A 1 337 ? 137.590 132.165 149.007 1.00 12.91  ? 316 ILE B CB  1 
ATOM   2303 C CG1 . ILE A 1 337 ? 138.834 131.643 149.717 1.00 17.91  ? 316 ILE B CG1 1 
ATOM   2304 C CG2 . ILE A 1 337 ? 137.398 133.636 149.309 1.00 17.86  ? 316 ILE B CG2 1 
ATOM   2305 C CD1 . ILE A 1 337 ? 140.117 132.269 149.230 1.00 22.53  ? 316 ILE B CD1 1 
ATOM   2306 N N   . ILE A 1 338 ? 134.142 132.337 149.215 1.00 15.18  ? 317 ILE B N   1 
ATOM   2307 C CA  . ILE A 1 338 ? 132.931 132.797 148.544 1.00 18.07  ? 317 ILE B CA  1 
ATOM   2308 C C   . ILE A 1 338 ? 133.002 134.314 148.455 1.00 18.48  ? 317 ILE B C   1 
ATOM   2309 O O   . ILE A 1 338 ? 132.836 135.013 149.459 1.00 24.47  ? 317 ILE B O   1 
ATOM   2310 C CB  . ILE A 1 338 ? 131.663 132.344 149.279 1.00 18.31  ? 317 ILE B CB  1 
ATOM   2311 C CG1 . ILE A 1 338 ? 131.823 130.932 149.847 1.00 19.87  ? 317 ILE B CG1 1 
ATOM   2312 C CG2 . ILE A 1 338 ? 130.462 132.414 148.366 1.00 11.35  ? 317 ILE B CG2 1 
ATOM   2313 C CD1 . ILE A 1 338 ? 132.257 129.896 148.829 1.00 25.15  ? 317 ILE B CD1 1 
ATOM   2314 N N   . VAL A 1 339 ? 133.238 134.827 147.254 1.00 18.80  ? 318 VAL B N   1 
ATOM   2315 C CA  . VAL A 1 339 ? 133.382 136.260 147.035 1.00 10.76  ? 318 VAL B CA  1 
ATOM   2316 C C   . VAL A 1 339 ? 132.027 136.844 146.671 1.00 5.13   ? 318 VAL B C   1 
ATOM   2317 O O   . VAL A 1 339 ? 131.320 136.313 145.809 1.00 21.51  ? 318 VAL B O   1 
ATOM   2318 C CB  . VAL A 1 339 ? 134.421 136.548 145.940 1.00 5.23   ? 318 VAL B CB  1 
ATOM   2319 C CG1 . VAL A 1 339 ? 134.573 138.038 145.739 1.00 13.67  ? 318 VAL B CG1 1 
ATOM   2320 C CG2 . VAL A 1 339 ? 135.753 135.927 146.303 1.00 8.27   ? 318 VAL B CG2 1 
ATOM   2321 N N   . SER A 1 340 ? 131.654 137.927 147.345 1.00 9.06   ? 319 SER B N   1 
ATOM   2322 C CA  . SER A 1 340 ? 130.444 138.667 147.029 1.00 0.00   ? 319 SER B CA  1 
ATOM   2323 C C   . SER A 1 340 ? 130.737 140.151 147.161 1.00 5.78   ? 319 SER B C   1 
ATOM   2324 O O   . SER A 1 340 ? 131.748 140.556 147.736 1.00 18.53  ? 319 SER B O   1 
ATOM   2325 C CB  . SER A 1 340 ? 129.272 138.267 147.931 1.00 8.40   ? 319 SER B CB  1 
ATOM   2326 O OG  . SER A 1 340 ? 129.648 138.277 149.294 1.00 26.83  ? 319 SER B OG  1 
ATOM   2327 N N   . TYR A 1 341 ? 129.849 140.960 146.597 1.00 17.03  ? 320 TYR B N   1 
ATOM   2328 C CA  . TYR A 1 341 ? 130.006 142.404 146.578 1.00 0.00   ? 320 TYR B CA  1 
ATOM   2329 C C   . TYR A 1 341 ? 128.709 143.060 147.016 1.00 11.23  ? 320 TYR B C   1 
ATOM   2330 O O   . TYR A 1 341 ? 127.619 142.523 146.803 1.00 16.97  ? 320 TYR B O   1 
ATOM   2331 C CB  . TYR A 1 341 ? 130.400 142.900 145.187 1.00 0.00   ? 320 TYR B CB  1 
ATOM   2332 C CG  . TYR A 1 341 ? 131.814 142.552 144.802 1.00 0.00   ? 320 TYR B CG  1 
ATOM   2333 C CD1 . TYR A 1 341 ? 132.112 141.341 144.201 1.00 0.00   ? 320 TYR B CD1 1 
ATOM   2334 C CD2 . TYR A 1 341 ? 132.850 143.433 145.047 1.00 0.00   ? 320 TYR B CD2 1 
ATOM   2335 C CE1 . TYR A 1 341 ? 133.401 141.020 143.858 1.00 0.00   ? 320 TYR B CE1 1 
ATOM   2336 C CE2 . TYR A 1 341 ? 134.140 143.121 144.708 1.00 4.22   ? 320 TYR B CE2 1 
ATOM   2337 C CZ  . TYR A 1 341 ? 134.411 141.914 144.113 1.00 4.71   ? 320 TYR B CZ  1 
ATOM   2338 O OH  . TYR A 1 341 ? 135.704 141.607 143.772 1.00 19.77  ? 320 TYR B OH  1 
ATOM   2339 N N   . LYS A 1 342 ? 128.837 144.226 147.642 1.00 20.59  ? 321 LYS B N   1 
ATOM   2340 C CA  . LYS A 1 342 ? 127.684 144.996 148.078 1.00 10.33  ? 321 LYS B CA  1 
ATOM   2341 C C   . LYS A 1 342 ? 127.991 146.478 147.950 1.00 16.86  ? 321 LYS B C   1 
ATOM   2342 O O   . LYS A 1 342 ? 129.149 146.899 147.955 1.00 14.53  ? 321 LYS B O   1 
ATOM   2343 C CB  . LYS A 1 342 ? 127.289 144.669 149.521 1.00 17.98  ? 321 LYS B CB  1 
ATOM   2344 C CG  . LYS A 1 342 ? 126.141 143.693 149.647 1.00 20.20  ? 321 LYS B CG  1 
ATOM   2345 C CD  . LYS A 1 342 ? 126.011 143.171 151.061 1.00 20.33  ? 321 LYS B CD  1 
ATOM   2346 C CE  . LYS A 1 342 ? 124.651 142.549 151.293 1.00 21.30  ? 321 LYS B CE  1 
ATOM   2347 N NZ  . LYS A 1 342 ? 124.653 141.100 150.968 1.00 28.83  ? 321 LYS B NZ  1 
ATOM   2348 N N   . VAL A 1 343 ? 126.928 147.266 147.835 1.00 27.65  ? 322 VAL B N   1 
ATOM   2349 C CA  . VAL A 1 343 ? 127.008 148.721 147.789 1.00 19.88  ? 322 VAL B CA  1 
ATOM   2350 C C   . VAL A 1 343 ? 126.378 149.247 149.069 1.00 20.47  ? 322 VAL B C   1 
ATOM   2351 O O   . VAL A 1 343 ? 125.226 148.924 149.378 1.00 28.34  ? 322 VAL B O   1 
ATOM   2352 C CB  . VAL A 1 343 ? 126.310 149.289 146.543 1.00 16.79  ? 322 VAL B CB  1 
ATOM   2353 C CG1 . VAL A 1 343 ? 125.846 150.715 146.785 1.00 18.58  ? 322 VAL B CG1 1 
ATOM   2354 C CG2 . VAL A 1 343 ? 127.239 149.234 145.347 1.00 16.00  ? 322 VAL B CG2 1 
ATOM   2355 N N   . LYS A 1 344 ? 127.133 150.040 149.821 1.00 25.94  ? 323 LYS B N   1 
ATOM   2356 C CA  . LYS A 1 344 ? 126.675 150.583 151.092 1.00 26.68  ? 323 LYS B CA  1 
ATOM   2357 C C   . LYS A 1 344 ? 126.398 152.073 150.949 1.00 29.11  ? 323 LYS B C   1 
ATOM   2358 O O   . LYS A 1 344 ? 127.267 152.831 150.507 1.00 35.43  ? 323 LYS B O   1 
ATOM   2359 C CB  . LYS A 1 344 ? 127.705 150.341 152.194 1.00 26.79  ? 323 LYS B CB  1 
ATOM   2360 C CG  . LYS A 1 344 ? 127.413 151.093 153.470 1.00 25.80  ? 323 LYS B CG  1 
ATOM   2361 C CD  . LYS A 1 344 ? 127.825 150.299 154.684 1.00 22.17  ? 323 LYS B CD  1 
ATOM   2362 C CE  . LYS A 1 344 ? 127.082 150.774 155.911 1.00 33.28  ? 323 LYS B CE  1 
ATOM   2363 N NZ  . LYS A 1 344 ? 127.107 149.759 156.999 1.00 42.97  ? 323 LYS B NZ  1 
ATOM   2364 N N   . VAL A 1 345 ? 125.195 152.487 151.334 1.00 26.13  ? 324 VAL B N   1 
ATOM   2365 C CA  . VAL A 1 345 ? 124.774 153.881 151.283 1.00 22.81  ? 324 VAL B CA  1 
ATOM   2366 C C   . VAL A 1 345 ? 124.536 154.344 152.712 1.00 35.34  ? 324 VAL B C   1 
ATOM   2367 O O   . VAL A 1 345 ? 123.641 153.832 153.395 1.00 36.77  ? 324 VAL B O   1 
ATOM   2368 C CB  . VAL A 1 345 ? 123.510 154.060 150.432 1.00 16.05  ? 324 VAL B CB  1 
ATOM   2369 C CG1 . VAL A 1 345 ? 122.968 155.470 150.572 1.00 21.28  ? 324 VAL B CG1 1 
ATOM   2370 C CG2 . VAL A 1 345 ? 123.801 153.722 148.988 1.00 24.45  ? 324 VAL B CG2 1 
ATOM   2371 N N   . LYS A 1 346 ? 125.321 155.319 153.159 1.00 42.31  ? 325 LYS B N   1 
ATOM   2372 C CA  . LYS A 1 346 ? 125.272 155.797 154.532 1.00 31.12  ? 325 LYS B CA  1 
ATOM   2373 C C   . LYS A 1 346 ? 124.924 157.278 154.569 1.00 37.19  ? 325 LYS B C   1 
ATOM   2374 O O   . LYS A 1 346 ? 125.452 158.070 153.784 1.00 37.63  ? 325 LYS B O   1 
ATOM   2375 C CB  . LYS A 1 346 ? 126.606 155.565 155.239 1.00 34.19  ? 325 LYS B CB  1 
ATOM   2376 C CG  . LYS A 1 346 ? 126.526 155.685 156.748 1.00 44.44  ? 325 LYS B CG  1 
ATOM   2377 C CD  . LYS A 1 346 ? 127.584 154.840 157.436 1.00 47.03  ? 325 LYS B CD  1 
ATOM   2378 C CE  . LYS A 1 346 ? 128.882 154.815 156.650 1.00 45.34  ? 325 LYS B CE  1 
ATOM   2379 N NZ  . LYS A 1 346 ? 130.063 154.912 157.548 1.00 41.43  ? 325 LYS B NZ  1 
ATOM   2380 N N   . LEU A 1 347 ? 124.031 157.640 155.486 1.00 38.68  ? 326 LEU B N   1 
ATOM   2381 C CA  . LEU A 1 347 ? 123.682 159.028 155.774 1.00 31.49  ? 326 LEU B CA  1 
ATOM   2382 C C   . LEU A 1 347 ? 124.076 159.317 157.213 1.00 33.64  ? 326 LEU B C   1 
ATOM   2383 O O   . LEU A 1 347 ? 123.502 158.740 158.141 1.00 45.45  ? 326 LEU B O   1 
ATOM   2384 C CB  . LEU A 1 347 ? 122.190 159.281 155.584 1.00 22.43  ? 326 LEU B CB  1 
ATOM   2385 C CG  . LEU A 1 347 ? 121.530 158.932 154.262 1.00 26.59  ? 326 LEU B CG  1 
ATOM   2386 C CD1 . LEU A 1 347 ? 120.036 159.053 154.431 1.00 30.48  ? 326 LEU B CD1 1 
ATOM   2387 C CD2 . LEU A 1 347 ? 122.023 159.855 153.175 1.00 35.41  ? 326 LEU B CD2 1 
ATOM   2388 N N   . VAL A 1 348 ? 125.036 160.199 157.405 1.00 38.44  ? 327 VAL B N   1 
ATOM   2389 C CA  . VAL A 1 348 ? 125.405 160.626 158.749 1.00 47.64  ? 327 VAL B CA  1 
ATOM   2390 C C   . VAL A 1 348 ? 124.506 161.787 159.150 1.00 48.30  ? 327 VAL B C   1 
ATOM   2391 O O   . VAL A 1 348 ? 124.139 162.629 158.322 1.00 48.54  ? 327 VAL B O   1 
ATOM   2392 C CB  . VAL A 1 348 ? 126.900 160.994 158.828 1.00 43.55  ? 327 VAL B CB  1 
ATOM   2393 C CG1 . VAL A 1 348 ? 127.730 159.962 158.093 1.00 41.04  ? 327 VAL B CG1 1 
ATOM   2394 C CG2 . VAL A 1 348 ? 127.162 162.374 158.270 1.00 46.15  ? 327 VAL B CG2 1 
ATOM   2395 N N   . VAL A 1 349 ? 124.103 161.807 160.415 1.00 49.18  ? 328 VAL B N   1 
ATOM   2396 C CA  . VAL A 1 349 ? 123.200 162.823 160.938 1.00 51.26  ? 328 VAL B CA  1 
ATOM   2397 C C   . VAL A 1 349 ? 123.870 163.454 162.148 1.00 58.55  ? 328 VAL B C   1 
ATOM   2398 O O   . VAL A 1 349 ? 124.084 162.785 163.167 1.00 64.65  ? 328 VAL B O   1 
ATOM   2399 C CB  . VAL A 1 349 ? 121.832 162.241 161.307 1.00 57.65  ? 328 VAL B CB  1 
ATOM   2400 C CG1 . VAL A 1 349 ? 121.041 163.242 162.122 1.00 62.98  ? 328 VAL B CG1 1 
ATOM   2401 C CG2 . VAL A 1 349 ? 121.070 161.848 160.053 1.00 54.15  ? 328 VAL B CG2 1 
ATOM   2402 N N   . SER A 1 350 ? 124.193 164.739 162.044 1.00 70.73  ? 329 SER B N   1 
ATOM   2403 C CA  . SER A 1 350 ? 124.872 165.433 163.127 1.00 73.64  ? 329 SER B CA  1 
ATOM   2404 C C   . SER A 1 350 ? 123.929 165.646 164.306 1.00 74.38  ? 329 SER B C   1 
ATOM   2405 O O   . SER A 1 350 ? 122.715 165.789 164.144 1.00 74.03  ? 329 SER B O   1 
ATOM   2406 C CB  . SER A 1 350 ? 125.416 166.775 162.640 1.00 73.55  ? 329 SER B CB  1 
ATOM   2407 O OG  . SER A 1 350 ? 126.609 166.597 161.897 1.00 72.23  ? 329 SER B OG  1 
ATOM   2408 N N   . ARG A 1 351 ? 124.505 165.662 165.507 1.00 88.33  ? 330 ARG B N   1 
ATOM   2409 C CA  . ARG A 1 351 ? 123.733 165.871 166.724 1.00 89.38  ? 330 ARG B CA  1 
ATOM   2410 C C   . ARG A 1 351 ? 124.560 166.687 167.704 1.00 91.44  ? 330 ARG B C   1 
ATOM   2411 O O   . ARG A 1 351 ? 125.712 166.343 167.983 1.00 92.20  ? 330 ARG B O   1 
ATOM   2412 C CB  . ARG A 1 351 ? 123.322 164.536 167.355 1.00 88.94  ? 330 ARG B CB  1 
ATOM   2413 N N   . GLY A 1 352 ? 123.969 167.761 168.223 1.00 101.69 ? 331 GLY B N   1 
ATOM   2414 C CA  . GLY A 1 352 ? 124.636 168.600 169.198 1.00 101.33 ? 331 GLY B CA  1 
ATOM   2415 C C   . GLY A 1 352 ? 123.985 168.543 170.565 1.00 101.97 ? 331 GLY B C   1 
ATOM   2416 O O   . GLY A 1 352 ? 123.586 167.468 171.024 1.00 100.58 ? 331 GLY B O   1 
ATOM   2417 N N   . GLY A 1 353 ? 123.867 169.693 171.223 1.00 105.36 ? 332 GLY B N   1 
ATOM   2418 C CA  . GLY A 1 353 ? 123.242 169.754 172.530 1.00 105.50 ? 332 GLY B CA  1 
ATOM   2419 C C   . GLY A 1 353 ? 124.020 169.011 173.596 1.00 105.95 ? 332 GLY B C   1 
ATOM   2420 O O   . GLY A 1 353 ? 125.085 169.463 174.026 1.00 104.60 ? 332 GLY B O   1 
ATOM   2421 N N   . LEU A 1 354 ? 123.487 167.869 174.037 1.00 109.97 ? 333 LEU B N   1 
ATOM   2422 C CA  . LEU A 1 354 ? 124.192 167.044 175.011 1.00 109.94 ? 333 LEU B CA  1 
ATOM   2423 C C   . LEU A 1 354 ? 125.507 166.506 174.463 1.00 110.05 ? 333 LEU B C   1 
ATOM   2424 O O   . LEU A 1 354 ? 126.410 166.191 175.245 1.00 109.13 ? 333 LEU B O   1 
ATOM   2425 C CB  . LEU A 1 354 ? 123.300 165.886 175.462 1.00 108.30 ? 333 LEU B CB  1 
ATOM   2426 N N   . LEU A 1 355 ? 125.631 166.390 173.144 1.00 108.32 ? 334 LEU B N   1 
ATOM   2427 C CA  . LEU A 1 355 ? 126.869 165.961 172.514 1.00 107.31 ? 334 LEU B CA  1 
ATOM   2428 C C   . LEU A 1 355 ? 127.714 167.188 172.167 1.00 107.61 ? 334 LEU B C   1 
ATOM   2429 O O   . LEU A 1 355 ? 127.419 168.312 172.581 1.00 105.44 ? 334 LEU B O   1 
ATOM   2430 C CB  . LEU A 1 355 ? 126.567 165.107 171.285 1.00 106.20 ? 334 LEU B CB  1 
ATOM   2431 N N   . GLY A 1 356 ? 128.781 166.981 171.401 1.00 111.75 ? 335 GLY B N   1 
ATOM   2432 C CA  . GLY A 1 356 ? 129.640 168.076 170.996 1.00 111.08 ? 335 GLY B CA  1 
ATOM   2433 C C   . GLY A 1 356 ? 129.624 168.318 169.502 1.00 111.15 ? 335 GLY B C   1 
ATOM   2434 O O   . GLY A 1 356 ? 130.664 168.616 168.906 1.00 110.81 ? 335 GLY B O   1 
ATOM   2435 N N   . ASP A 1 357 ? 128.446 168.183 168.889 1.00 107.66 ? 336 ASP B N   1 
ATOM   2436 C CA  . ASP A 1 357 ? 128.264 168.374 167.448 1.00 107.39 ? 336 ASP B CA  1 
ATOM   2437 C C   . ASP A 1 357 ? 129.143 167.426 166.636 1.00 106.94 ? 336 ASP B C   1 
ATOM   2438 O O   . ASP A 1 357 ? 129.505 167.722 165.494 1.00 105.11 ? 336 ASP B O   1 
ATOM   2439 C CB  . ASP A 1 357 ? 128.520 169.827 167.039 1.00 104.48 ? 336 ASP B CB  1 
ATOM   2440 N N   . LEU A 1 358 ? 129.494 166.279 167.221 1.00 100.36 ? 337 LEU B N   1 
ATOM   2441 C CA  . LEU A 1 358 ? 130.320 165.288 166.550 1.00 99.76  ? 337 LEU B CA  1 
ATOM   2442 C C   . LEU A 1 358 ? 129.788 163.868 166.690 1.00 100.67 ? 337 LEU B C   1 
ATOM   2443 O O   . LEU A 1 358 ? 130.338 162.957 166.061 1.00 100.58 ? 337 LEU B O   1 
ATOM   2444 C CB  . LEU A 1 358 ? 131.762 165.343 167.079 1.00 100.16 ? 337 LEU B CB  1 
ATOM   2445 N N   . ALA A 1 359 ? 128.748 163.651 167.492 1.00 91.05  ? 338 ALA B N   1 
ATOM   2446 C CA  . ALA A 1 359 ? 128.117 162.342 167.618 1.00 89.07  ? 338 ALA B CA  1 
ATOM   2447 C C   . ALA A 1 359 ? 127.101 162.197 166.492 1.00 89.89  ? 338 ALA B C   1 
ATOM   2448 O O   . ALA A 1 359 ? 126.029 162.809 166.531 1.00 89.72  ? 338 ALA B O   1 
ATOM   2449 C CB  . ALA A 1 359 ? 127.456 162.185 168.984 1.00 87.62  ? 338 ALA B CB  1 
ATOM   2450 N N   . SER A 1 360 ? 127.438 161.391 165.490 1.00 73.78  ? 339 SER B N   1 
ATOM   2451 C CA  . SER A 1 360 ? 126.646 161.275 164.273 1.00 72.47  ? 339 SER B CA  1 
ATOM   2452 C C   . SER A 1 360 ? 125.970 159.912 164.228 1.00 72.88  ? 339 SER B C   1 
ATOM   2453 O O   . SER A 1 360 ? 126.639 158.878 164.327 1.00 73.28  ? 339 SER B O   1 
ATOM   2454 C CB  . SER A 1 360 ? 127.521 161.481 163.036 1.00 70.43  ? 339 SER B CB  1 
ATOM   2455 O OG  . SER A 1 360 ? 127.929 162.832 162.922 1.00 70.94  ? 339 SER B OG  1 
ATOM   2456 N N   . SER A 1 361 ? 124.648 159.915 164.071 1.00 64.42  ? 340 SER B N   1 
ATOM   2457 C CA  . SER A 1 361 ? 123.886 158.692 163.868 1.00 62.98  ? 340 SER B CA  1 
ATOM   2458 C C   . SER A 1 361 ? 123.841 158.373 162.380 1.00 60.12  ? 340 SER B C   1 
ATOM   2459 O O   . SER A 1 361 ? 123.447 159.217 161.570 1.00 58.79  ? 340 SER B O   1 
ATOM   2460 C CB  . SER A 1 361 ? 122.469 158.834 164.424 1.00 63.23  ? 340 SER B CB  1 
ATOM   2461 O OG  . SER A 1 361 ? 121.648 157.752 164.018 1.00 63.22  ? 340 SER B OG  1 
ATOM   2462 N N   . ASP A 1 362 ? 124.242 157.157 162.027 1.00 47.71  ? 341 ASP B N   1 
ATOM   2463 C CA  . ASP A 1 362 ? 124.368 156.750 160.635 1.00 45.70  ? 341 ASP B CA  1 
ATOM   2464 C C   . ASP A 1 362 ? 123.191 155.871 160.237 1.00 45.37  ? 341 ASP B C   1 
ATOM   2465 O O   . ASP A 1 362 ? 122.895 154.877 160.908 1.00 50.23  ? 341 ASP B O   1 
ATOM   2466 C CB  . ASP A 1 362 ? 125.681 156.003 160.407 1.00 49.11  ? 341 ASP B CB  1 
ATOM   2467 C CG  . ASP A 1 362 ? 126.896 156.855 160.714 1.00 54.84  ? 341 ASP B CG  1 
ATOM   2468 O OD1 . ASP A 1 362 ? 126.766 157.824 161.490 1.00 52.29  ? 341 ASP B OD1 1 
ATOM   2469 O OD2 . ASP A 1 362 ? 127.984 156.553 160.181 1.00 55.82  ? 341 ASP B OD2 1 
ATOM   2470 N N   . VAL A 1 363 ? 122.527 156.240 159.148 1.00 34.68  ? 342 VAL B N   1 
ATOM   2471 C CA  . VAL A 1 363 ? 121.478 155.432 158.542 1.00 28.40  ? 342 VAL B CA  1 
ATOM   2472 C C   . VAL A 1 363 ? 122.076 154.752 157.320 1.00 32.03  ? 342 VAL B C   1 
ATOM   2473 O O   . VAL A 1 363 ? 122.576 155.424 156.411 1.00 39.85  ? 342 VAL B O   1 
ATOM   2474 C CB  . VAL A 1 363 ? 120.259 156.286 158.169 1.00 32.13  ? 342 VAL B CB  1 
ATOM   2475 C CG1 . VAL A 1 363 ? 119.366 155.540 157.204 1.00 36.09  ? 342 VAL B CG1 1 
ATOM   2476 C CG2 . VAL A 1 363 ? 119.493 156.673 159.416 1.00 34.72  ? 342 VAL B CG2 1 
ATOM   2477 N N   . ALA A 1 364 ? 122.034 153.424 157.292 1.00 30.35  ? 343 ALA B N   1 
ATOM   2478 C CA  . ALA A 1 364 ? 122.775 152.650 156.311 1.00 20.71  ? 343 ALA B CA  1 
ATOM   2479 C C   . ALA A 1 364 ? 121.847 151.790 155.466 1.00 24.56  ? 343 ALA B C   1 
ATOM   2480 O O   . ALA A 1 364 ? 120.825 151.288 155.940 1.00 26.65  ? 343 ALA B O   1 
ATOM   2481 C CB  . ALA A 1 364 ? 123.820 151.761 156.986 1.00 23.93  ? 343 ALA B CB  1 
ATOM   2482 N N   . VAL A 1 365 ? 122.230 151.634 154.202 1.00 35.84  ? 344 VAL B N   1 
ATOM   2483 C CA  . VAL A 1 365 ? 121.551 150.789 153.229 1.00 17.49  ? 344 VAL B CA  1 
ATOM   2484 C C   . VAL A 1 365 ? 122.611 149.985 152.493 1.00 19.35  ? 344 VAL B C   1 
ATOM   2485 O O   . VAL A 1 365 ? 123.631 150.541 152.074 1.00 29.14  ? 344 VAL B O   1 
ATOM   2486 C CB  . VAL A 1 365 ? 120.715 151.624 152.241 1.00 22.90  ? 344 VAL B CB  1 
ATOM   2487 C CG1 . VAL A 1 365 ? 120.121 150.752 151.174 1.00 27.65  ? 344 VAL B CG1 1 
ATOM   2488 C CG2 . VAL A 1 365 ? 119.609 152.334 152.970 1.00 27.23  ? 344 VAL B CG2 1 
ATOM   2489 N N   . GLU A 1 366 ? 122.382 148.683 152.346 1.00 29.34  ? 345 GLU B N   1 
ATOM   2490 C CA  . GLU A 1 366 ? 123.300 147.807 151.631 1.00 18.25  ? 345 GLU B CA  1 
ATOM   2491 C C   . GLU A 1 366 ? 122.586 147.174 150.447 1.00 19.88  ? 345 GLU B C   1 
ATOM   2492 O O   . GLU A 1 366 ? 121.464 146.676 150.586 1.00 25.38  ? 345 GLU B O   1 
ATOM   2493 C CB  . GLU A 1 366 ? 123.868 146.728 152.549 1.00 19.04  ? 345 GLU B CB  1 
ATOM   2494 C CG  . GLU A 1 366 ? 125.365 146.562 152.413 1.00 25.01  ? 345 GLU B CG  1 
ATOM   2495 C CD  . GLU A 1 366 ? 126.006 146.001 153.661 1.00 38.45  ? 345 GLU B CD  1 
ATOM   2496 O OE1 . GLU A 1 366 ? 127.248 146.060 153.769 1.00 39.17  ? 345 GLU B OE1 1 
ATOM   2497 O OE2 . GLU A 1 366 ? 125.268 145.498 154.533 1.00 40.19  ? 345 GLU B OE2 1 
ATOM   2498 N N   . LEU A 1 367 ? 123.239 147.197 149.287 1.00 19.60  ? 346 LEU B N   1 
ATOM   2499 C CA  . LEU A 1 367 ? 122.679 146.663 148.050 1.00 19.20  ? 346 LEU B CA  1 
ATOM   2500 C C   . LEU A 1 367 ? 123.649 145.642 147.473 1.00 23.54  ? 346 LEU B C   1 
ATOM   2501 O O   . LEU A 1 367 ? 124.808 145.994 147.175 1.00 24.71  ? 346 LEU B O   1 
ATOM   2502 C CB  . LEU A 1 367 ? 122.414 147.780 147.041 1.00 15.72  ? 346 LEU B CB  1 
ATOM   2503 C CG  . LEU A 1 367 ? 121.425 148.858 147.463 1.00 8.46   ? 346 LEU B CG  1 
ATOM   2504 C CD1 . LEU A 1 367 ? 121.798 150.170 146.819 1.00 13.50  ? 346 LEU B CD1 1 
ATOM   2505 C CD2 . LEU A 1 367 ? 120.036 148.451 147.060 1.00 21.56  ? 346 LEU B CD2 1 
ATOM   2506 N N   . PRO A 1 368 ? 123.242 144.385 147.300 1.00 17.82  ? 347 PRO B N   1 
ATOM   2507 C CA  . PRO A 1 368 ? 124.131 143.388 146.693 1.00 14.44  ? 347 PRO B CA  1 
ATOM   2508 C C   . PRO A 1 368 ? 124.059 143.378 145.174 1.00 23.11  ? 347 PRO B C   1 
ATOM   2509 O O   . PRO A 1 368 ? 122.994 143.514 144.569 1.00 26.06  ? 347 PRO B O   1 
ATOM   2510 C CB  . PRO A 1 368 ? 123.604 142.072 147.277 1.00 15.88  ? 347 PRO B CB  1 
ATOM   2511 C CG  . PRO A 1 368 ? 122.156 142.321 147.481 1.00 15.02  ? 347 PRO B CG  1 
ATOM   2512 C CD  . PRO A 1 368 ? 121.980 143.790 147.768 1.00 11.73  ? 347 PRO B CD  1 
ATOM   2513 N N   . PHE A 1 369 ? 125.222 143.208 144.551 1.00 17.38  ? 348 PHE B N   1 
ATOM   2514 C CA  . PHE A 1 369 ? 125.318 143.157 143.101 1.00 3.66   ? 348 PHE B CA  1 
ATOM   2515 C C   . PHE A 1 369 ? 126.330 142.093 142.703 1.00 7.11   ? 348 PHE B C   1 
ATOM   2516 O O   . PHE A 1 369 ? 127.135 141.636 143.515 1.00 14.36  ? 348 PHE B O   1 
ATOM   2517 C CB  . PHE A 1 369 ? 125.695 144.523 142.505 1.00 16.85  ? 348 PHE B CB  1 
ATOM   2518 C CG  . PHE A 1 369 ? 127.117 144.935 142.761 1.00 6.96   ? 348 PHE B CG  1 
ATOM   2519 C CD1 . PHE A 1 369 ? 127.480 145.503 143.966 1.00 0.00   ? 348 PHE B CD1 1 
ATOM   2520 C CD2 . PHE A 1 369 ? 128.086 144.767 141.791 1.00 6.25   ? 348 PHE B CD2 1 
ATOM   2521 C CE1 . PHE A 1 369 ? 128.777 145.881 144.200 1.00 0.00   ? 348 PHE B CE1 1 
ATOM   2522 C CE2 . PHE A 1 369 ? 129.384 145.144 142.024 1.00 0.00   ? 348 PHE B CE2 1 
ATOM   2523 C CZ  . PHE A 1 369 ? 129.728 145.705 143.229 1.00 0.00   ? 348 PHE B CZ  1 
ATOM   2524 N N   . THR A 1 370 ? 126.270 141.694 141.436 1.00 18.37  ? 349 THR B N   1 
ATOM   2525 C CA  . THR A 1 370 ? 127.105 140.630 140.895 1.00 14.78  ? 349 THR B CA  1 
ATOM   2526 C C   . THR A 1 370 ? 128.201 141.233 140.029 1.00 6.86   ? 349 THR B C   1 
ATOM   2527 O O   . THR A 1 370 ? 127.924 142.062 139.159 1.00 16.03  ? 349 THR B O   1 
ATOM   2528 C CB  . THR A 1 370 ? 126.267 139.644 140.078 1.00 7.15   ? 349 THR B CB  1 
ATOM   2529 O OG1 . THR A 1 370 ? 125.019 139.416 140.739 1.00 12.12  ? 349 THR B OG1 1 
ATOM   2530 C CG2 . THR A 1 370 ? 126.983 138.328 139.940 1.00 16.32  ? 349 THR B CG2 1 
ATOM   2531 N N   . LEU A 1 371 ? 129.439 140.817 140.271 1.00 5.62   ? 350 LEU B N   1 
ATOM   2532 C CA  . LEU A 1 371 ? 130.604 141.296 139.531 1.00 0.00   ? 350 LEU B CA  1 
ATOM   2533 C C   . LEU A 1 371 ? 131.244 140.100 138.836 1.00 11.90  ? 350 LEU B C   1 
ATOM   2534 O O   . LEU A 1 371 ? 131.964 139.321 139.464 1.00 8.47   ? 350 LEU B O   1 
ATOM   2535 C CB  . LEU A 1 371 ? 131.590 141.995 140.460 1.00 0.00   ? 350 LEU B CB  1 
ATOM   2536 C CG  . LEU A 1 371 ? 132.644 142.889 139.816 1.00 0.00   ? 350 LEU B CG  1 
ATOM   2537 C CD1 . LEU A 1 371 ? 131.988 144.025 139.065 1.00 12.90  ? 350 LEU B CD1 1 
ATOM   2538 C CD2 . LEU A 1 371 ? 133.587 143.419 140.866 1.00 1.64   ? 350 LEU B CD2 1 
ATOM   2539 N N   . MET A 1 372 ? 130.982 139.955 137.541 1.00 11.66  ? 351 MET B N   1 
ATOM   2540 C CA  . MET A 1 372 ? 131.483 138.839 136.754 1.00 4.20   ? 351 MET B CA  1 
ATOM   2541 C C   . MET A 1 372 ? 132.011 139.353 135.426 1.00 5.36   ? 351 MET B C   1 
ATOM   2542 O O   . MET A 1 372 ? 131.856 140.524 135.079 1.00 10.09  ? 351 MET B O   1 
ATOM   2543 C CB  . MET A 1 372 ? 130.399 137.784 136.499 1.00 10.18  ? 351 MET B CB  1 
ATOM   2544 C CG  . MET A 1 372 ? 129.576 137.385 137.699 1.00 0.00   ? 351 MET B CG  1 
ATOM   2545 S SD  . MET A 1 372 ? 129.382 135.598 137.779 1.00 20.16  ? 351 MET B SD  1 
ATOM   2546 C CE  . MET A 1 372 ? 131.031 135.101 138.239 1.00 14.65  ? 351 MET B CE  1 
ATOM   2547 N N   . HIS A 1 373 ? 132.647 138.457 134.687 1.00 9.62   ? 352 HIS B N   1 
ATOM   2548 C CA  . HIS A 1 373 ? 133.066 138.581 133.299 1.00 0.00   ? 352 HIS B CA  1 
ATOM   2549 C C   . HIS A 1 373 ? 131.967 138.045 132.387 1.00 10.54  ? 352 HIS B C   1 
ATOM   2550 O O   . HIS A 1 373 ? 131.326 137.044 132.716 1.00 24.98  ? 352 HIS B O   1 
ATOM   2551 C CB  . HIS A 1 373 ? 134.351 137.796 133.049 1.00 4.89   ? 352 HIS B CB  1 
ATOM   2552 C CG  . HIS A 1 373 ? 135.598 138.511 133.460 1.00 0.00   ? 352 HIS B CG  1 
ATOM   2553 N ND1 . HIS A 1 373 ? 135.951 139.742 132.957 1.00 12.36  ? 352 HIS B ND1 1 
ATOM   2554 C CD2 . HIS A 1 373 ? 136.588 138.156 134.311 1.00 0.00   ? 352 HIS B CD2 1 
ATOM   2555 C CE1 . HIS A 1 373 ? 137.099 140.120 133.488 1.00 3.88   ? 352 HIS B CE1 1 
ATOM   2556 N NE2 . HIS A 1 373 ? 137.508 139.174 134.312 1.00 0.00   ? 352 HIS B NE2 1 
ATOM   2557 N N   . PRO A 1 374 ? 131.701 138.677 131.249 1.00 7.14   ? 353 PRO B N   1 
ATOM   2558 C CA  . PRO A 1 374 ? 130.764 138.089 130.289 1.00 10.55  ? 353 PRO B CA  1 
ATOM   2559 C C   . PRO A 1 374 ? 131.364 136.858 129.628 1.00 16.46  ? 353 PRO B C   1 
ATOM   2560 O O   . PRO A 1 374 ? 132.579 136.651 129.621 1.00 23.48  ? 353 PRO B O   1 
ATOM   2561 C CB  . PRO A 1 374 ? 130.530 139.215 129.279 1.00 9.01   ? 353 PRO B CB  1 
ATOM   2562 C CG  . PRO A 1 374 ? 131.721 140.079 129.392 1.00 3.88   ? 353 PRO B CG  1 
ATOM   2563 C CD  . PRO A 1 374 ? 132.202 139.988 130.805 1.00 12.06  ? 353 PRO B CD  1 
ATOM   2564 N N   . LYS A 1 375 ? 130.489 136.028 129.078 1.00 15.55  ? 354 LYS B N   1 
ATOM   2565 C CA  . LYS A 1 375 ? 130.924 134.773 128.473 1.00 13.03  ? 354 LYS B CA  1 
ATOM   2566 C C   . LYS A 1 375 ? 131.811 135.051 127.266 1.00 23.46  ? 354 LYS B C   1 
ATOM   2567 O O   . LYS A 1 375 ? 131.363 135.705 126.316 1.00 29.62  ? 354 LYS B O   1 
ATOM   2568 C CB  . LYS A 1 375 ? 129.716 133.940 128.062 1.00 20.25  ? 354 LYS B CB  1 
ATOM   2569 C CG  . LYS A 1 375 ? 129.737 132.512 128.578 1.00 29.20  ? 354 LYS B CG  1 
ATOM   2570 C CD  . LYS A 1 375 ? 130.647 131.628 127.738 1.00 26.82  ? 354 LYS B CD  1 
ATOM   2571 C CE  . LYS A 1 375 ? 131.019 130.352 128.482 1.00 29.39  ? 354 LYS B CE  1 
ATOM   2572 N NZ  . LYS A 1 375 ? 131.965 129.504 127.711 1.00 25.70  ? 354 LYS B NZ  1 
ATOM   2573 N N   . PRO A 1 376 ? 133.056 134.574 127.253 1.00 27.62  ? 355 PRO B N   1 
ATOM   2574 C CA  . PRO A 1 376 ? 133.974 134.921 126.163 1.00 23.50  ? 355 PRO B CA  1 
ATOM   2575 C C   . PRO A 1 376 ? 133.942 133.923 125.022 1.00 23.73  ? 355 PRO B C   1 
ATOM   2576 O O   . PRO A 1 376 ? 133.186 132.948 125.056 1.00 34.49  ? 355 PRO B O   1 
ATOM   2577 C CB  . PRO A 1 376 ? 135.336 134.923 126.860 1.00 28.98  ? 355 PRO B CB  1 
ATOM   2578 C CG  . PRO A 1 376 ? 135.196 133.859 127.889 1.00 24.81  ? 355 PRO B CG  1 
ATOM   2579 C CD  . PRO A 1 376 ? 133.741 133.831 128.320 1.00 27.02  ? 355 PRO B CD  1 
ATOM   2580 N N   . LYS A 1 377 ? 134.765 134.163 124.002 1.00 35.72  ? 356 LYS B N   1 
ATOM   2581 C CA  . LYS A 1 377 ? 134.877 133.264 122.864 1.00 36.28  ? 356 LYS B CA  1 
ATOM   2582 C C   . LYS A 1 377 ? 136.221 132.554 122.778 1.00 37.63  ? 356 LYS B C   1 
ATOM   2583 O O   . LYS A 1 377 ? 136.375 131.665 121.933 1.00 33.61  ? 356 LYS B O   1 
ATOM   2584 C CB  . LYS A 1 377 ? 134.626 134.029 121.556 1.00 28.87  ? 356 LYS B CB  1 
ATOM   2585 N N   . GLU A 1 378 ? 137.189 132.907 123.621 1.00 40.96  ? 357 GLU B N   1 
ATOM   2586 C CA  . GLU A 1 378 ? 138.520 132.314 123.554 1.00 41.92  ? 357 GLU B CA  1 
ATOM   2587 C C   . GLU A 1 378 ? 139.141 132.330 124.948 1.00 46.75  ? 357 GLU B C   1 
ATOM   2588 O O   . GLU A 1 378 ? 138.482 132.652 125.940 1.00 39.48  ? 357 GLU B O   1 
ATOM   2589 C CB  . GLU A 1 378 ? 139.388 133.055 122.529 1.00 38.20  ? 357 GLU B CB  1 
ATOM   2590 N N   . GLU A 1 379 ? 140.419 131.970 125.016 1.00 50.97  ? 358 GLU B N   1 
ATOM   2591 C CA  . GLU A 1 379 ? 141.134 131.958 126.288 1.00 40.47  ? 358 GLU B CA  1 
ATOM   2592 C C   . GLU A 1 379 ? 141.411 133.386 126.746 1.00 45.61  ? 358 GLU B C   1 
ATOM   2593 O O   . GLU A 1 379 ? 141.915 134.193 125.959 1.00 44.32  ? 358 GLU B O   1 
ATOM   2594 C CB  . GLU A 1 379 ? 142.445 131.186 126.154 1.00 38.33  ? 358 GLU B CB  1 
ATOM   2595 N N   . PRO A 1 380 ? 141.123 133.721 128.001 1.00 46.84  ? 359 PRO B N   1 
ATOM   2596 C CA  . PRO A 1 380 ? 141.231 135.118 128.470 1.00 35.42  ? 359 PRO B CA  1 
ATOM   2597 C C   . PRO A 1 380 ? 142.601 135.743 128.241 1.00 38.61  ? 359 PRO B C   1 
ATOM   2598 O O   . PRO A 1 380 ? 142.671 136.923 127.871 1.00 48.16  ? 359 PRO B O   1 
ATOM   2599 C CB  . PRO A 1 380 ? 140.921 135.013 129.971 1.00 31.28  ? 359 PRO B CB  1 
ATOM   2600 C CG  . PRO A 1 380 ? 140.244 133.705 130.168 1.00 40.20  ? 359 PRO B CG  1 
ATOM   2601 C CD  . PRO A 1 380 ? 140.357 132.872 128.929 1.00 40.74  ? 359 PRO B CD  1 
ATOM   2602 N N   . PRO A 1 381 ? 143.727 135.023 128.451 1.00 46.38  ? 360 PRO B N   1 
ATOM   2603 C CA  . PRO A 1 381 ? 145.015 135.737 128.452 1.00 45.61  ? 360 PRO B CA  1 
ATOM   2604 C C   . PRO A 1 381 ? 145.462 136.264 127.095 1.00 46.47  ? 360 PRO B C   1 
ATOM   2605 O O   . PRO A 1 381 ? 146.277 135.628 126.422 1.00 50.37  ? 360 PRO B O   1 
ATOM   2606 C CB  . PRO A 1 381 ? 146.003 134.681 128.972 1.00 49.42  ? 360 PRO B CB  1 
ATOM   2607 C CG  . PRO A 1 381 ? 145.170 133.688 129.675 1.00 49.00  ? 360 PRO B CG  1 
ATOM   2608 C CD  . PRO A 1 381 ? 143.920 133.622 128.873 1.00 44.08  ? 360 PRO B CD  1 
ATOM   2609 N N   . HIS A 1 382 ? 144.935 137.420 126.679 1.00 41.69  ? 361 HIS B N   1 
ATOM   2610 C CA  . HIS A 1 382 ? 145.504 138.165 125.560 1.00 38.16  ? 361 HIS B CA  1 
ATOM   2611 C C   . HIS A 1 382 ? 146.413 139.306 125.999 1.00 40.46  ? 361 HIS B C   1 
ATOM   2612 O O   . HIS A 1 382 ? 146.996 139.973 125.138 1.00 45.33  ? 361 HIS B O   1 
ATOM   2613 C CB  . HIS A 1 382 ? 144.416 138.755 124.645 1.00 24.85  ? 361 HIS B CB  1 
ATOM   2614 C CG  . HIS A 1 382 ? 143.189 137.911 124.496 1.00 34.94  ? 361 HIS B CG  1 
ATOM   2615 N ND1 . HIS A 1 382 ? 142.382 137.561 125.556 1.00 37.48  ? 361 HIS B ND1 1 
ATOM   2616 C CD2 . HIS A 1 382 ? 142.611 137.376 123.394 1.00 41.40  ? 361 HIS B CD2 1 
ATOM   2617 C CE1 . HIS A 1 382 ? 141.366 136.840 125.116 1.00 34.87  ? 361 HIS B CE1 1 
ATOM   2618 N NE2 . HIS A 1 382 ? 141.485 136.708 123.808 1.00 46.77  ? 361 HIS B NE2 1 
ATOM   2619 N N   . ARG A 1 383 ? 146.549 139.546 127.302 1.00 44.77  ? 362 ARG B N   1 
ATOM   2620 C CA  . ARG A 1 383 ? 147.225 140.748 127.776 1.00 47.37  ? 362 ARG B CA  1 
ATOM   2621 C C   . ARG A 1 383 ? 148.696 140.745 127.385 1.00 46.72  ? 362 ARG B C   1 
ATOM   2622 O O   . ARG A 1 383 ? 149.417 139.775 127.632 1.00 42.40  ? 362 ARG B O   1 
ATOM   2623 C CB  . ARG A 1 383 ? 147.087 140.861 129.293 1.00 40.77  ? 362 ARG B CB  1 
ATOM   2624 C CG  . ARG A 1 383 ? 145.664 141.066 129.776 1.00 42.14  ? 362 ARG B CG  1 
ATOM   2625 C CD  . ARG A 1 383 ? 145.644 141.762 131.126 1.00 45.77  ? 362 ARG B CD  1 
ATOM   2626 N NE  . ARG A 1 383 ? 146.735 141.307 131.978 1.00 45.44  ? 362 ARG B NE  1 
ATOM   2627 C CZ  . ARG A 1 383 ? 147.399 142.081 132.824 1.00 45.04  ? 362 ARG B CZ  1 
ATOM   2628 N NH1 . ARG A 1 383 ? 147.097 143.360 132.973 1.00 43.00  ? 362 ARG B NH1 1 
ATOM   2629 N NH2 . ARG A 1 383 ? 148.393 141.560 133.537 1.00 43.28  ? 362 ARG B NH2 1 
ATOM   2630 N N   . GLU A 1 384 ? 149.142 141.845 126.784 1.00 38.57  ? 363 GLU B N   1 
ATOM   2631 C CA  . GLU A 1 384 ? 150.541 141.977 126.405 1.00 41.07  ? 363 GLU B CA  1 
ATOM   2632 C C   . GLU A 1 384 ? 151.418 142.067 127.648 1.00 43.53  ? 363 GLU B C   1 
ATOM   2633 O O   . GLU A 1 384 ? 151.104 142.791 128.596 1.00 41.81  ? 363 GLU B O   1 
ATOM   2634 C CB  . GLU A 1 384 ? 150.741 143.212 125.528 1.00 26.86  ? 363 GLU B CB  1 
ATOM   2635 N N   . VAL A 1 385 ? 152.520 141.333 127.640 1.00 41.87  ? 364 VAL B N   1 
ATOM   2636 C CA  . VAL A 1 385 ? 153.444 141.271 128.770 1.00 42.21  ? 364 VAL B CA  1 
ATOM   2637 C C   . VAL A 1 385 ? 154.732 141.986 128.380 1.00 38.79  ? 364 VAL B C   1 
ATOM   2638 O O   . VAL A 1 385 ? 155.224 141.787 127.264 1.00 39.38  ? 364 VAL B O   1 
ATOM   2639 C CB  . VAL A 1 385 ? 153.717 139.817 129.217 1.00 48.37  ? 364 VAL B CB  1 
ATOM   2640 C CG1 . VAL A 1 385 ? 152.423 139.029 129.239 1.00 45.46  ? 364 VAL B CG1 1 
ATOM   2641 C CG2 . VAL A 1 385 ? 154.724 139.115 128.324 1.00 41.34  ? 364 VAL B CG2 1 
ATOM   2642 N N   . PRO A 1 386 ? 155.269 142.873 129.230 1.00 50.38  ? 365 PRO B N   1 
ATOM   2643 C CA  . PRO A 1 386 ? 156.520 143.582 128.941 1.00 54.23  ? 365 PRO B CA  1 
ATOM   2644 C C   . PRO A 1 386 ? 157.751 142.694 129.111 1.00 52.57  ? 365 PRO B C   1 
ATOM   2645 O O   . PRO A 1 386 ? 158.862 143.145 128.832 1.00 51.80  ? 365 PRO B O   1 
ATOM   2646 C CB  . PRO A 1 386 ? 156.527 144.716 129.968 1.00 44.18  ? 365 PRO B CB  1 
ATOM   2647 C CG  . PRO A 1 386 ? 155.674 144.220 131.075 1.00 44.66  ? 365 PRO B CG  1 
ATOM   2648 C CD  . PRO A 1 386 ? 154.611 143.386 130.443 1.00 43.22  ? 365 PRO B CD  1 
ATOM   2649 N N   . GLU B 2 24  ? 126.549 154.910 120.656 1.00 44.16  ? 24  GLU D N   1 
ATOM   2650 C CA  . GLU B 2 24  ? 127.566 155.245 119.666 1.00 46.00  ? 24  GLU D CA  1 
ATOM   2651 C C   . GLU B 2 24  ? 128.944 155.343 120.308 1.00 46.33  ? 24  GLU D C   1 
ATOM   2652 O O   . GLU B 2 24  ? 129.105 155.932 121.375 1.00 47.86  ? 24  GLU D O   1 
ATOM   2653 C CB  . GLU B 2 24  ? 127.220 156.559 118.964 1.00 39.60  ? 24  GLU D CB  1 
ATOM   2654 N N   . VAL B 2 25  ? 129.937 154.761 119.644 1.00 34.75  ? 25  VAL D N   1 
ATOM   2655 C CA  . VAL B 2 25  ? 131.317 154.753 120.111 1.00 29.65  ? 25  VAL D CA  1 
ATOM   2656 C C   . VAL B 2 25  ? 132.153 155.576 119.146 1.00 33.87  ? 25  VAL D C   1 
ATOM   2657 O O   . VAL B 2 25  ? 132.102 155.357 117.931 1.00 42.50  ? 25  VAL D O   1 
ATOM   2658 C CB  . VAL B 2 25  ? 131.865 153.322 120.225 1.00 37.24  ? 25  VAL D CB  1 
ATOM   2659 C CG1 . VAL B 2 25  ? 133.113 153.304 121.078 1.00 33.38  ? 25  VAL D CG1 1 
ATOM   2660 C CG2 . VAL B 2 25  ? 130.809 152.398 120.805 1.00 36.64  ? 25  VAL D CG2 1 
ATOM   2661 N N   . GLN B 2 26  ? 132.910 156.527 119.683 1.00 29.67  ? 26  GLN D N   1 
ATOM   2662 C CA  . GLN B 2 26  ? 133.792 157.333 118.856 1.00 31.29  ? 26  GLN D CA  1 
ATOM   2663 C C   . GLN B 2 26  ? 134.874 157.946 119.728 1.00 28.34  ? 26  GLN D C   1 
ATOM   2664 O O   . GLN B 2 26  ? 134.641 158.271 120.893 1.00 31.36  ? 26  GLN D O   1 
ATOM   2665 C CB  . GLN B 2 26  ? 133.026 158.432 118.113 1.00 34.46  ? 26  GLN D CB  1 
ATOM   2666 C CG  . GLN B 2 26  ? 131.855 159.006 118.879 1.00 33.03  ? 26  GLN D CG  1 
ATOM   2667 C CD  . GLN B 2 26  ? 130.970 159.868 118.009 1.00 37.28  ? 26  GLN D CD  1 
ATOM   2668 O OE1 . GLN B 2 26  ? 131.088 159.857 116.783 1.00 32.94  ? 26  GLN D OE1 1 
ATOM   2669 N NE2 . GLN B 2 26  ? 130.076 160.621 118.636 1.00 42.95  ? 26  GLN D NE2 1 
ATOM   2670 N N   . LEU B 2 27  ? 136.058 158.094 119.146 1.00 22.28  ? 27  LEU D N   1 
ATOM   2671 C CA  . LEU B 2 27  ? 137.170 158.795 119.767 1.00 14.65  ? 27  LEU D CA  1 
ATOM   2672 C C   . LEU B 2 27  ? 137.463 160.035 118.939 1.00 25.56  ? 27  LEU D C   1 
ATOM   2673 O O   . LEU B 2 27  ? 137.663 159.939 117.725 1.00 37.84  ? 27  LEU D O   1 
ATOM   2674 C CB  . LEU B 2 27  ? 138.415 157.908 119.856 1.00 16.32  ? 27  LEU D CB  1 
ATOM   2675 C CG  . LEU B 2 27  ? 138.274 156.538 120.520 1.00 17.08  ? 27  LEU D CG  1 
ATOM   2676 C CD1 . LEU B 2 27  ? 137.964 155.483 119.488 1.00 18.95  ? 27  LEU D CD1 1 
ATOM   2677 C CD2 . LEU B 2 27  ? 139.534 156.177 121.271 1.00 15.64  ? 27  LEU D CD2 1 
ATOM   2678 N N   . VAL B 2 28  ? 137.472 161.193 119.588 1.00 21.48  ? 28  VAL D N   1 
ATOM   2679 C CA  . VAL B 2 28  ? 137.699 162.467 118.919 1.00 25.88  ? 28  VAL D CA  1 
ATOM   2680 C C   . VAL B 2 28  ? 139.011 163.041 119.423 1.00 25.72  ? 28  VAL D C   1 
ATOM   2681 O O   . VAL B 2 28  ? 139.215 163.170 120.635 1.00 31.96  ? 28  VAL D O   1 
ATOM   2682 C CB  . VAL B 2 28  ? 136.541 163.450 119.159 1.00 30.37  ? 28  VAL D CB  1 
ATOM   2683 C CG1 . VAL B 2 28  ? 136.705 164.675 118.278 1.00 28.00  ? 28  VAL D CG1 1 
ATOM   2684 C CG2 . VAL B 2 28  ? 135.203 162.775 118.899 1.00 26.62  ? 28  VAL D CG2 1 
ATOM   2685 N N   . GLU B 2 29  ? 139.898 163.379 118.499 1.00 21.79  ? 29  GLU D N   1 
ATOM   2686 C CA  . GLU B 2 29  ? 141.178 163.977 118.833 1.00 24.64  ? 29  GLU D CA  1 
ATOM   2687 C C   . GLU B 2 29  ? 141.101 165.493 118.722 1.00 26.26  ? 29  GLU D C   1 
ATOM   2688 O O   . GLU B 2 29  ? 140.227 166.052 118.056 1.00 27.30  ? 29  GLU D O   1 
ATOM   2689 C CB  . GLU B 2 29  ? 142.287 163.448 117.923 1.00 28.30  ? 29  GLU D CB  1 
ATOM   2690 C CG  . GLU B 2 29  ? 142.748 162.055 118.261 1.00 21.41  ? 29  GLU D CG  1 
ATOM   2691 C CD  . GLU B 2 29  ? 142.078 161.014 117.404 1.00 23.12  ? 29  GLU D CD  1 
ATOM   2692 O OE1 . GLU B 2 29  ? 140.895 160.719 117.650 1.00 24.43  ? 29  GLU D OE1 1 
ATOM   2693 O OE2 . GLU B 2 29  ? 142.734 160.490 116.485 1.00 35.09  ? 29  GLU D OE2 1 
ATOM   2694 N N   . SER B 2 30  ? 142.039 166.153 119.391 1.00 27.28  ? 30  SER D N   1 
ATOM   2695 C CA  . SER B 2 30  ? 142.142 167.602 119.351 1.00 21.12  ? 30  SER D CA  1 
ATOM   2696 C C   . SER B 2 30  ? 143.545 167.986 119.789 1.00 25.38  ? 30  SER D C   1 
ATOM   2697 O O   . SER B 2 30  ? 144.328 167.147 120.236 1.00 30.81  ? 30  SER D O   1 
ATOM   2698 C CB  . SER B 2 30  ? 141.081 168.263 120.234 1.00 29.88  ? 30  SER D CB  1 
ATOM   2699 O OG  . SER B 2 30  ? 141.101 167.725 121.543 1.00 34.04  ? 30  SER D OG  1 
ATOM   2700 N N   . GLY B 2 31  ? 143.853 169.270 119.652 1.00 38.31  ? 31  GLY D N   1 
ATOM   2701 C CA  . GLY B 2 31  ? 145.137 169.784 120.094 1.00 44.49  ? 31  GLY D CA  1 
ATOM   2702 C C   . GLY B 2 31  ? 146.328 169.284 119.307 1.00 43.84  ? 31  GLY D C   1 
ATOM   2703 O O   . GLY B 2 31  ? 147.375 168.989 119.895 1.00 48.38  ? 31  GLY D O   1 
ATOM   2704 N N   . GLY B 2 32  ? 146.196 169.184 117.990 1.00 31.29  ? 32  GLY D N   1 
ATOM   2705 C CA  . GLY B 2 32  ? 147.316 168.809 117.153 1.00 34.69  ? 32  GLY D CA  1 
ATOM   2706 C C   . GLY B 2 32  ? 147.562 169.829 116.065 1.00 42.93  ? 32  GLY D C   1 
ATOM   2707 O O   . GLY B 2 32  ? 146.679 170.089 115.243 1.00 48.77  ? 32  GLY D O   1 
ATOM   2708 N N   . GLY B 2 33  ? 148.752 170.415 116.046 1.00 30.74  ? 33  GLY D N   1 
ATOM   2709 C CA  . GLY B 2 33  ? 149.038 171.447 115.080 1.00 27.02  ? 33  GLY D CA  1 
ATOM   2710 C C   . GLY B 2 33  ? 150.522 171.684 114.939 1.00 32.23  ? 33  GLY D C   1 
ATOM   2711 O O   . GLY B 2 33  ? 151.346 170.942 115.476 1.00 33.64  ? 33  GLY D O   1 
ATOM   2712 N N   . LEU B 2 34  ? 150.849 172.740 114.200 1.00 38.48  ? 34  LEU D N   1 
ATOM   2713 C CA  . LEU B 2 34  ? 152.239 173.063 113.908 1.00 40.00  ? 34  LEU D CA  1 
ATOM   2714 C C   . LEU B 2 34  ? 152.962 173.526 115.167 1.00 42.83  ? 34  LEU D C   1 
ATOM   2715 O O   . LEU B 2 34  ? 152.439 174.343 115.930 1.00 42.80  ? 34  LEU D O   1 
ATOM   2716 C CB  . LEU B 2 34  ? 152.298 174.142 112.828 1.00 34.68  ? 34  LEU D CB  1 
ATOM   2717 C CG  . LEU B 2 34  ? 153.573 174.973 112.717 1.00 41.54  ? 34  LEU D CG  1 
ATOM   2718 C CD1 . LEU B 2 34  ? 154.740 174.125 112.243 1.00 36.37  ? 34  LEU D CD1 1 
ATOM   2719 C CD2 . LEU B 2 34  ? 153.339 176.148 111.785 1.00 45.27  ? 34  LEU D CD2 1 
ATOM   2720 N N   . VAL B 2 35  ? 154.170 173.004 115.381 1.00 36.01  ? 35  VAL D N   1 
ATOM   2721 C CA  . VAL B 2 35  ? 155.020 173.379 116.502 1.00 34.69  ? 35  VAL D CA  1 
ATOM   2722 C C   . VAL B 2 35  ? 156.461 173.478 116.015 1.00 37.79  ? 35  VAL D C   1 
ATOM   2723 O O   . VAL B 2 35  ? 156.765 173.236 114.845 1.00 40.83  ? 35  VAL D O   1 
ATOM   2724 C CB  . VAL B 2 35  ? 154.916 172.389 117.678 1.00 28.14  ? 35  VAL D CB  1 
ATOM   2725 C CG1 . VAL B 2 35  ? 153.691 172.691 118.512 1.00 37.55  ? 35  VAL D CG1 1 
ATOM   2726 C CG2 . VAL B 2 35  ? 154.880 170.975 117.165 1.00 24.83  ? 35  VAL D CG2 1 
ATOM   2727 N N   . GLN B 2 36  ? 157.353 173.832 116.933 1.00 41.59  ? 36  GLN D N   1 
ATOM   2728 C CA  . GLN B 2 36  ? 158.766 174.040 116.669 1.00 39.31  ? 36  GLN D CA  1 
ATOM   2729 C C   . GLN B 2 36  ? 159.592 172.888 117.227 1.00 34.84  ? 36  GLN D C   1 
ATOM   2730 O O   . GLN B 2 36  ? 159.163 172.197 118.155 1.00 34.39  ? 36  GLN D O   1 
ATOM   2731 C CB  . GLN B 2 36  ? 159.235 175.363 117.290 1.00 40.62  ? 36  GLN D CB  1 
ATOM   2732 C CG  . GLN B 2 36  ? 158.140 176.407 117.434 1.00 43.68  ? 36  GLN D CG  1 
ATOM   2733 C CD  . GLN B 2 36  ? 157.773 177.060 116.115 1.00 47.62  ? 36  GLN D CD  1 
ATOM   2734 O OE1 . GLN B 2 36  ? 156.600 177.126 115.745 1.00 43.10  ? 36  GLN D OE1 1 
ATOM   2735 N NE2 . GLN B 2 36  ? 158.778 177.552 115.400 1.00 47.11  ? 36  GLN D NE2 1 
ATOM   2736 N N   . PRO B 2 37  ? 160.791 172.653 116.686 1.00 34.20  ? 37  PRO D N   1 
ATOM   2737 C CA  . PRO B 2 37  ? 161.587 171.505 117.138 1.00 38.76  ? 37  PRO D CA  1 
ATOM   2738 C C   . PRO B 2 37  ? 162.144 171.688 118.540 1.00 45.00  ? 37  PRO D C   1 
ATOM   2739 O O   . PRO B 2 37  ? 163.298 172.087 118.723 1.00 45.56  ? 37  PRO D O   1 
ATOM   2740 C CB  . PRO B 2 37  ? 162.706 171.420 116.092 1.00 34.81  ? 37  PRO D CB  1 
ATOM   2741 C CG  . PRO B 2 37  ? 162.801 172.781 115.529 1.00 42.12  ? 37  PRO D CG  1 
ATOM   2742 C CD  . PRO B 2 37  ? 161.408 173.326 115.531 1.00 40.75  ? 37  PRO D CD  1 
ATOM   2743 N N   . GLY B 2 38  ? 161.320 171.385 119.538 1.00 41.52  ? 38  GLY D N   1 
ATOM   2744 C CA  . GLY B 2 38  ? 161.685 171.550 120.928 1.00 30.61  ? 38  GLY D CA  1 
ATOM   2745 C C   . GLY B 2 38  ? 160.485 171.965 121.748 1.00 34.96  ? 38  GLY D C   1 
ATOM   2746 O O   . GLY B 2 38  ? 160.540 172.005 122.979 1.00 39.46  ? 38  GLY D O   1 
ATOM   2747 N N   . GLY B 2 39  ? 159.387 172.269 121.063 1.00 38.57  ? 39  GLY D N   1 
ATOM   2748 C CA  . GLY B 2 39  ? 158.149 172.659 121.709 1.00 32.49  ? 39  GLY D CA  1 
ATOM   2749 C C   . GLY B 2 39  ? 157.430 171.489 122.341 1.00 30.97  ? 39  GLY D C   1 
ATOM   2750 O O   . GLY B 2 39  ? 158.035 170.474 122.704 1.00 30.78  ? 39  GLY D O   1 
ATOM   2751 N N   . SER B 2 40  ? 156.115 171.630 122.481 1.00 28.22  ? 40  SER D N   1 
ATOM   2752 C CA  . SER B 2 40  ? 155.317 170.637 123.183 1.00 27.62  ? 40  SER D CA  1 
ATOM   2753 C C   . SER B 2 40  ? 153.850 170.841 122.843 1.00 28.27  ? 40  SER D C   1 
ATOM   2754 O O   . SER B 2 40  ? 153.402 171.973 122.644 1.00 32.60  ? 40  SER D O   1 
ATOM   2755 C CB  . SER B 2 40  ? 155.523 170.734 124.701 1.00 31.41  ? 40  SER D CB  1 
ATOM   2756 O OG  . SER B 2 40  ? 156.880 170.531 125.058 1.00 36.92  ? 40  SER D OG  1 
ATOM   2757 N N   . LEU B 2 41  ? 153.109 169.737 122.788 1.00 20.31  ? 41  LEU D N   1 
ATOM   2758 C CA  . LEU B 2 41  ? 151.658 169.775 122.695 1.00 16.98  ? 41  LEU D CA  1 
ATOM   2759 C C   . LEU B 2 41  ? 151.057 168.827 123.717 1.00 12.37  ? 41  LEU D C   1 
ATOM   2760 O O   . LEU B 2 41  ? 151.757 168.070 124.392 1.00 16.25  ? 41  LEU D O   1 
ATOM   2761 C CB  . LEU B 2 41  ? 151.141 169.394 121.302 1.00 23.86  ? 41  LEU D CB  1 
ATOM   2762 C CG  . LEU B 2 41  ? 151.590 170.158 120.063 1.00 27.31  ? 41  LEU D CG  1 
ATOM   2763 C CD1 . LEU B 2 41  ? 152.536 169.309 119.250 1.00 23.16  ? 41  LEU D CD1 1 
ATOM   2764 C CD2 . LEU B 2 41  ? 150.379 170.557 119.243 1.00 27.07  ? 41  LEU D CD2 1 
ATOM   2765 N N   . ARG B 2 42  ? 149.733 168.876 123.814 1.00 14.62  ? 42  ARG D N   1 
ATOM   2766 C CA  . ARG B 2 42  ? 148.970 167.958 124.654 1.00 17.97  ? 42  ARG D CA  1 
ATOM   2767 C C   . ARG B 2 42  ? 147.789 167.478 123.819 1.00 28.86  ? 42  ARG D C   1 
ATOM   2768 O O   . ARG B 2 42  ? 146.829 168.224 123.602 1.00 30.28  ? 42  ARG D O   1 
ATOM   2769 C CB  . ARG B 2 42  ? 148.512 168.626 125.943 1.00 18.98  ? 42  ARG D CB  1 
ATOM   2770 C CG  . ARG B 2 42  ? 147.456 167.848 126.696 1.00 16.03  ? 42  ARG D CG  1 
ATOM   2771 C CD  . ARG B 2 42  ? 147.038 168.570 127.956 1.00 28.32  ? 42  ARG D CD  1 
ATOM   2772 N NE  . ARG B 2 42  ? 147.668 167.991 129.135 1.00 32.69  ? 42  ARG D NE  1 
ATOM   2773 C CZ  . ARG B 2 42  ? 147.041 167.762 130.279 1.00 35.05  ? 42  ARG D CZ  1 
ATOM   2774 N NH1 . ARG B 2 42  ? 145.764 168.066 130.439 1.00 32.35  ? 42  ARG D NH1 1 
ATOM   2775 N NH2 . ARG B 2 42  ? 147.711 167.214 131.287 1.00 28.29  ? 42  ARG D NH2 1 
ATOM   2776 N N   . LEU B 2 43  ? 147.871 166.242 123.339 1.00 28.81  ? 43  LEU D N   1 
ATOM   2777 C CA  . LEU B 2 43  ? 146.792 165.671 122.552 1.00 22.43  ? 43  LEU D CA  1 
ATOM   2778 C C   . LEU B 2 43  ? 145.681 165.175 123.463 1.00 23.64  ? 43  LEU D C   1 
ATOM   2779 O O   . LEU B 2 43  ? 145.933 164.544 124.491 1.00 26.16  ? 43  LEU D O   1 
ATOM   2780 C CB  . LEU B 2 43  ? 147.306 164.529 121.682 1.00 23.51  ? 43  LEU D CB  1 
ATOM   2781 C CG  . LEU B 2 43  ? 148.046 164.932 120.409 1.00 22.78  ? 43  LEU D CG  1 
ATOM   2782 C CD1 . LEU B 2 43  ? 148.486 163.701 119.650 1.00 15.73  ? 43  LEU D CD1 1 
ATOM   2783 C CD2 . LEU B 2 43  ? 147.179 165.811 119.539 1.00 26.05  ? 43  LEU D CD2 1 
ATOM   2784 N N   . SER B 2 44  ? 144.445 165.467 123.076 1.00 24.17  ? 44  SER D N   1 
ATOM   2785 C CA  . SER B 2 44  ? 143.265 165.104 123.844 1.00 25.89  ? 44  SER D CA  1 
ATOM   2786 C C   . SER B 2 44  ? 142.409 164.160 123.016 1.00 27.38  ? 44  SER D C   1 
ATOM   2787 O O   . SER B 2 44  ? 142.072 164.470 121.870 1.00 32.30  ? 44  SER D O   1 
ATOM   2788 C CB  . SER B 2 44  ? 142.468 166.350 124.233 1.00 26.06  ? 44  SER D CB  1 
ATOM   2789 O OG  . SER B 2 44  ? 141.306 166.010 124.963 1.00 36.47  ? 44  SER D OG  1 
ATOM   2790 N N   . CYS B 2 45  ? 142.061 163.017 123.592 1.00 24.74  ? 45  CYS D N   1 
ATOM   2791 C CA  . CYS B 2 45  ? 141.213 162.029 122.933 1.00 22.22  ? 45  CYS D CA  1 
ATOM   2792 C C   . CYS B 2 45  ? 139.913 161.933 123.721 1.00 29.11  ? 45  CYS D C   1 
ATOM   2793 O O   . CYS B 2 45  ? 139.840 161.233 124.733 1.00 36.93  ? 45  CYS D O   1 
ATOM   2794 C CB  . CYS B 2 45  ? 141.909 160.677 122.838 1.00 18.56  ? 45  CYS D CB  1 
ATOM   2795 S SG  . CYS B 2 45  ? 140.927 159.406 122.018 1.00 41.18  ? 45  CYS D SG  1 
ATOM   2796 N N   . ALA B 2 46  ? 138.887 162.636 123.251 1.00 32.92  ? 46  ALA D N   1 
ATOM   2797 C CA  . ALA B 2 46  ? 137.593 162.617 123.917 1.00 32.43  ? 46  ALA D CA  1 
ATOM   2798 C C   . ALA B 2 46  ? 136.877 161.304 123.638 1.00 31.01  ? 46  ALA D C   1 
ATOM   2799 O O   . ALA B 2 46  ? 136.095 161.203 122.688 1.00 33.95  ? 46  ALA D O   1 
ATOM   2800 C CB  . ALA B 2 46  ? 136.738 163.802 123.468 1.00 34.86  ? 46  ALA D CB  1 
ATOM   2801 N N   . ALA B 2 47  ? 137.146 160.296 124.459 1.00 21.33  ? 47  ALA D N   1 
ATOM   2802 C CA  . ALA B 2 47  ? 136.529 158.991 124.276 1.00 26.74  ? 47  ALA D CA  1 
ATOM   2803 C C   . ALA B 2 47  ? 135.048 159.048 124.623 1.00 21.83  ? 47  ALA D C   1 
ATOM   2804 O O   . ALA B 2 47  ? 134.658 159.628 125.641 1.00 25.16  ? 47  ALA D O   1 
ATOM   2805 C CB  . ALA B 2 47  ? 137.236 157.953 125.141 1.00 30.56  ? 47  ALA D CB  1 
ATOM   2806 N N   . SER B 2 48  ? 134.222 158.443 123.776 1.00 25.36  ? 48  SER D N   1 
ATOM   2807 C CA  . SER B 2 48  ? 132.784 158.393 123.981 1.00 24.02  ? 48  SER D CA  1 
ATOM   2808 C C   . SER B 2 48  ? 132.296 156.970 123.772 1.00 29.72  ? 48  SER D C   1 
ATOM   2809 O O   . SER B 2 48  ? 132.892 156.197 123.019 1.00 41.56  ? 48  SER D O   1 
ATOM   2810 C CB  . SER B 2 48  ? 132.037 159.336 123.030 1.00 30.84  ? 48  SER D CB  1 
ATOM   2811 O OG  . SER B 2 48  ? 132.447 160.678 123.212 1.00 35.86  ? 48  SER D OG  1 
ATOM   2812 N N   . GLY B 2 49  ? 131.209 156.627 124.454 1.00 30.94  ? 49  GLY D N   1 
ATOM   2813 C CA  . GLY B 2 49  ? 130.591 155.334 124.286 1.00 28.43  ? 49  GLY D CA  1 
ATOM   2814 C C   . GLY B 2 49  ? 131.165 154.219 125.129 1.00 25.22  ? 49  GLY D C   1 
ATOM   2815 O O   . GLY B 2 49  ? 130.628 153.106 125.096 1.00 32.54  ? 49  GLY D O   1 
ATOM   2816 N N   . PHE B 2 50  ? 132.233 154.469 125.880 1.00 8.90   ? 50  PHE D N   1 
ATOM   2817 C CA  . PHE B 2 50  ? 132.786 153.450 126.760 1.00 17.66  ? 50  PHE D CA  1 
ATOM   2818 C C   . PHE B 2 50  ? 133.410 154.135 127.969 1.00 15.75  ? 50  PHE D C   1 
ATOM   2819 O O   . PHE B 2 50  ? 133.225 155.335 128.191 1.00 22.85  ? 50  PHE D O   1 
ATOM   2820 C CB  . PHE B 2 50  ? 133.785 152.557 126.012 1.00 26.40  ? 50  PHE D CB  1 
ATOM   2821 C CG  . PHE B 2 50  ? 134.898 153.306 125.342 1.00 19.99  ? 50  PHE D CG  1 
ATOM   2822 C CD1 . PHE B 2 50  ? 136.007 153.717 126.056 1.00 9.86   ? 50  PHE D CD1 1 
ATOM   2823 C CD2 . PHE B 2 50  ? 134.844 153.576 123.991 1.00 22.73  ? 50  PHE D CD2 1 
ATOM   2824 C CE1 . PHE B 2 50  ? 137.029 154.398 125.437 1.00 14.13  ? 50  PHE D CE1 1 
ATOM   2825 C CE2 . PHE B 2 50  ? 135.862 154.257 123.366 1.00 26.60  ? 50  PHE D CE2 1 
ATOM   2826 C CZ  . PHE B 2 50  ? 136.957 154.666 124.090 1.00 27.48  ? 50  PHE D CZ  1 
ATOM   2827 N N   . ASN B 2 51  ? 134.154 153.358 128.754 1.00 20.44  ? 51  ASN D N   1 
ATOM   2828 C CA  . ASN B 2 51  ? 134.736 153.808 130.007 1.00 15.23  ? 51  ASN D CA  1 
ATOM   2829 C C   . ASN B 2 51  ? 136.227 153.516 129.998 1.00 13.56  ? 51  ASN D C   1 
ATOM   2830 O O   . ASN B 2 51  ? 136.684 152.582 129.337 1.00 20.11  ? 51  ASN D O   1 
ATOM   2831 C CB  . ASN B 2 51  ? 134.075 153.115 131.199 1.00 23.28  ? 51  ASN D CB  1 
ATOM   2832 C CG  . ASN B 2 51  ? 132.642 152.712 130.912 1.00 35.36  ? 51  ASN D CG  1 
ATOM   2833 O OD1 . ASN B 2 51  ? 132.353 151.543 130.657 1.00 20.66  ? 51  ASN D OD1 1 
ATOM   2834 N ND2 . ASN B 2 51  ? 131.736 153.681 130.945 1.00 32.96  ? 51  ASN D ND2 1 
ATOM   2835 N N   . VAL B 2 52  ? 136.987 154.327 130.738 1.00 14.23  ? 52  VAL D N   1 
ATOM   2836 C CA  . VAL B 2 52  ? 138.435 154.165 130.758 1.00 9.53   ? 52  VAL D CA  1 
ATOM   2837 C C   . VAL B 2 52  ? 138.871 152.978 131.601 1.00 6.93   ? 52  VAL D C   1 
ATOM   2838 O O   . VAL B 2 52  ? 140.020 152.539 131.492 1.00 21.84  ? 52  VAL D O   1 
ATOM   2839 C CB  . VAL B 2 52  ? 139.127 155.447 131.259 1.00 23.65  ? 52  VAL D CB  1 
ATOM   2840 C CG1 . VAL B 2 52  ? 138.992 156.560 130.236 1.00 16.41  ? 52  VAL D CG1 1 
ATOM   2841 C CG2 . VAL B 2 52  ? 138.547 155.874 132.595 1.00 15.26  ? 52  VAL D CG2 1 
ATOM   2842 N N   . TYR B 2 53  ? 137.995 152.446 132.445 1.00 10.65  ? 53  TYR D N   1 
ATOM   2843 C CA  . TYR B 2 53  ? 138.370 151.326 133.297 1.00 7.04   ? 53  TYR D CA  1 
ATOM   2844 C C   . TYR B 2 53  ? 138.183 149.980 132.619 1.00 10.13  ? 53  TYR D C   1 
ATOM   2845 O O   . TYR B 2 53  ? 138.954 149.052 132.883 1.00 19.04  ? 53  TYR D O   1 
ATOM   2846 C CB  . TYR B 2 53  ? 137.567 151.364 134.599 1.00 6.04   ? 53  TYR D CB  1 
ATOM   2847 C CG  . TYR B 2 53  ? 137.854 152.583 135.434 1.00 5.29   ? 53  TYR D CG  1 
ATOM   2848 C CD1 . TYR B 2 53  ? 139.120 152.815 135.930 1.00 0.41   ? 53  TYR D CD1 1 
ATOM   2849 C CD2 . TYR B 2 53  ? 136.864 153.509 135.714 1.00 9.49   ? 53  TYR D CD2 1 
ATOM   2850 C CE1 . TYR B 2 53  ? 139.397 153.927 136.683 1.00 6.61   ? 53  TYR D CE1 1 
ATOM   2851 C CE2 . TYR B 2 53  ? 137.131 154.623 136.474 1.00 15.36  ? 53  TYR D CE2 1 
ATOM   2852 C CZ  . TYR B 2 53  ? 138.401 154.826 136.955 1.00 16.29  ? 53  TYR D CZ  1 
ATOM   2853 O OH  . TYR B 2 53  ? 138.682 155.933 137.715 1.00 25.14  ? 53  TYR D OH  1 
ATOM   2854 N N   . SER B 2 54  ? 137.184 149.851 131.751 1.00 11.83  ? 54  SER D N   1 
ATOM   2855 C CA  . SER B 2 54  ? 136.936 148.620 131.020 1.00 0.00   ? 54  SER D CA  1 
ATOM   2856 C C   . SER B 2 54  ? 137.620 148.598 129.664 1.00 6.71   ? 54  SER D C   1 
ATOM   2857 O O   . SER B 2 54  ? 137.396 147.667 128.886 1.00 12.89  ? 54  SER D O   1 
ATOM   2858 C CB  . SER B 2 54  ? 135.434 148.403 130.846 1.00 6.60   ? 54  SER D CB  1 
ATOM   2859 O OG  . SER B 2 54  ? 134.836 149.504 130.191 1.00 16.90  ? 54  SER D OG  1 
ATOM   2860 N N   . SER B 2 55  ? 138.448 149.593 129.363 1.00 16.97  ? 55  SER D N   1 
ATOM   2861 C CA  . SER B 2 55  ? 139.139 149.645 128.087 1.00 0.00   ? 55  SER D CA  1 
ATOM   2862 C C   . SER B 2 55  ? 140.522 150.244 128.287 1.00 2.48   ? 55  SER D C   1 
ATOM   2863 O O   . SER B 2 55  ? 140.802 150.891 129.297 1.00 13.30  ? 55  SER D O   1 
ATOM   2864 C CB  . SER B 2 55  ? 138.351 150.454 127.053 1.00 0.00   ? 55  SER D CB  1 
ATOM   2865 O OG  . SER B 2 55  ? 138.279 151.815 127.421 1.00 8.45   ? 55  SER D OG  1 
ATOM   2866 N N   . SER B 2 56  ? 141.391 150.004 127.313 1.00 1.53   ? 56  SER D N   1 
ATOM   2867 C CA  . SER B 2 56  ? 142.712 150.607 127.270 1.00 0.00   ? 56  SER D CA  1 
ATOM   2868 C C   . SER B 2 56  ? 142.772 151.619 126.136 1.00 3.68   ? 56  SER D C   1 
ATOM   2869 O O   . SER B 2 56  ? 142.129 151.452 125.097 1.00 13.78  ? 56  SER D O   1 
ATOM   2870 C CB  . SER B 2 56  ? 143.804 149.554 127.081 1.00 5.21   ? 56  SER D CB  1 
ATOM   2871 O OG  . SER B 2 56  ? 143.977 148.781 128.250 1.00 17.02  ? 56  SER D OG  1 
ATOM   2872 N N   . ILE B 2 57  ? 143.537 152.683 126.350 1.00 6.58   ? 57  ILE D N   1 
ATOM   2873 C CA  . ILE B 2 57  ? 143.690 153.754 125.376 1.00 0.00   ? 57  ILE D CA  1 
ATOM   2874 C C   . ILE B 2 57  ? 145.124 153.741 124.880 1.00 2.01   ? 57  ILE D C   1 
ATOM   2875 O O   . ILE B 2 57  ? 146.064 153.729 125.681 1.00 4.32   ? 57  ILE D O   1 
ATOM   2876 C CB  . ILE B 2 57  ? 143.325 155.123 125.970 1.00 4.10   ? 57  ILE D CB  1 
ATOM   2877 C CG1 . ILE B 2 57  ? 141.952 155.062 126.635 1.00 0.00   ? 57  ILE D CG1 1 
ATOM   2878 C CG2 . ILE B 2 57  ? 143.353 156.184 124.888 1.00 7.51   ? 57  ILE D CG2 1 
ATOM   2879 C CD1 . ILE B 2 57  ? 140.815 154.911 125.667 1.00 0.00   ? 57  ILE D CD1 1 
ATOM   2880 N N   . HIS B 2 58  ? 145.289 153.741 123.564 1.00 4.43   ? 58  HIS D N   1 
ATOM   2881 C CA  . HIS B 2 58  ? 146.593 153.654 122.935 1.00 4.84   ? 58  HIS D CA  1 
ATOM   2882 C C   . HIS B 2 58  ? 146.778 154.826 121.987 1.00 4.01   ? 58  HIS D C   1 
ATOM   2883 O O   . HIS B 2 58  ? 145.810 155.391 121.477 1.00 20.09  ? 58  HIS D O   1 
ATOM   2884 C CB  . HIS B 2 58  ? 146.753 152.333 122.177 1.00 0.00   ? 58  HIS D CB  1 
ATOM   2885 C CG  . HIS B 2 58  ? 146.296 151.139 122.952 1.00 0.00   ? 58  HIS D CG  1 
ATOM   2886 N ND1 . HIS B 2 58  ? 147.167 150.319 123.634 1.00 2.58   ? 58  HIS D ND1 1 
ATOM   2887 C CD2 . HIS B 2 58  ? 145.060 150.633 123.164 1.00 8.21   ? 58  HIS D CD2 1 
ATOM   2888 C CE1 . HIS B 2 58  ? 146.486 149.361 124.235 1.00 9.19   ? 58  HIS D CE1 1 
ATOM   2889 N NE2 . HIS B 2 58  ? 145.206 149.528 123.964 1.00 2.35   ? 58  HIS D NE2 1 
ATOM   2890 N N   . TRP B 2 59  ? 148.032 155.198 121.769 1.00 4.67   ? 59  TRP D N   1 
ATOM   2891 C CA  . TRP B 2 59  ? 148.382 156.256 120.835 1.00 9.36   ? 59  TRP D CA  1 
ATOM   2892 C C   . TRP B 2 59  ? 149.259 155.662 119.746 1.00 7.67   ? 59  TRP D C   1 
ATOM   2893 O O   . TRP B 2 59  ? 150.363 155.186 120.023 1.00 10.09  ? 59  TRP D O   1 
ATOM   2894 C CB  . TRP B 2 59  ? 149.084 157.412 121.551 1.00 14.57  ? 59  TRP D CB  1 
ATOM   2895 C CG  . TRP B 2 59  ? 148.131 158.268 122.329 1.00 14.04  ? 59  TRP D CG  1 
ATOM   2896 C CD1 . TRP B 2 59  ? 147.847 158.179 123.657 1.00 6.31   ? 59  TRP D CD1 1 
ATOM   2897 C CD2 . TRP B 2 59  ? 147.332 159.338 121.820 1.00 4.03   ? 59  TRP D CD2 1 
ATOM   2898 N NE1 . TRP B 2 59  ? 146.919 159.125 124.008 1.00 8.13   ? 59  TRP D NE1 1 
ATOM   2899 C CE2 . TRP B 2 59  ? 146.589 159.853 122.898 1.00 2.21   ? 59  TRP D CE2 1 
ATOM   2900 C CE3 . TRP B 2 59  ? 147.175 159.913 120.558 1.00 0.00   ? 59  TRP D CE3 1 
ATOM   2901 C CZ2 . TRP B 2 59  ? 145.706 160.912 122.753 1.00 0.00   ? 59  TRP D CZ2 1 
ATOM   2902 C CZ3 . TRP B 2 59  ? 146.299 160.963 120.416 1.00 10.90  ? 59  TRP D CZ3 1 
ATOM   2903 C CH2 . TRP B 2 59  ? 145.574 161.453 121.506 1.00 13.85  ? 59  TRP D CH2 1 
ATOM   2904 N N   . VAL B 2 60  ? 148.755 155.675 118.517 1.00 3.22   ? 60  VAL D N   1 
ATOM   2905 C CA  . VAL B 2 60  ? 149.438 155.117 117.359 1.00 0.00   ? 60  VAL D CA  1 
ATOM   2906 C C   . VAL B 2 60  ? 149.610 156.233 116.343 1.00 0.00   ? 60  VAL D C   1 
ATOM   2907 O O   . VAL B 2 60  ? 148.640 156.914 115.996 1.00 12.28  ? 60  VAL D O   1 
ATOM   2908 C CB  . VAL B 2 60  ? 148.656 153.936 116.755 1.00 13.70  ? 60  VAL D CB  1 
ATOM   2909 C CG1 . VAL B 2 60  ? 149.296 153.473 115.461 1.00 10.84  ? 60  VAL D CG1 1 
ATOM   2910 C CG2 . VAL B 2 60  ? 148.570 152.792 117.747 1.00 3.94   ? 60  VAL D CG2 1 
ATOM   2911 N N   . ARG B 2 61  ? 150.836 156.428 115.878 1.00 0.00   ? 61  ARG D N   1 
ATOM   2912 C CA  . ARG B 2 61  ? 151.145 157.485 114.931 1.00 2.75   ? 61  ARG D CA  1 
ATOM   2913 C C   . ARG B 2 61  ? 151.615 156.896 113.611 1.00 9.70   ? 61  ARG D C   1 
ATOM   2914 O O   . ARG B 2 61  ? 152.168 155.796 113.561 1.00 31.12  ? 61  ARG D O   1 
ATOM   2915 C CB  . ARG B 2 61  ? 152.216 158.425 115.482 1.00 19.00  ? 61  ARG D CB  1 
ATOM   2916 C CG  . ARG B 2 61  ? 153.609 157.838 115.494 1.00 18.36  ? 61  ARG D CG  1 
ATOM   2917 C CD  . ARG B 2 61  ? 154.589 158.818 116.074 1.00 16.79  ? 61  ARG D CD  1 
ATOM   2918 N NE  . ARG B 2 61  ? 155.882 158.211 116.351 1.00 18.88  ? 61  ARG D NE  1 
ATOM   2919 C CZ  . ARG B 2 61  ? 156.786 158.729 117.167 1.00 22.53  ? 61  ARG D CZ  1 
ATOM   2920 N NH1 . ARG B 2 61  ? 156.560 159.857 117.820 1.00 16.89  ? 61  ARG D NH1 1 
ATOM   2921 N NH2 . ARG B 2 61  ? 157.945 158.101 117.334 1.00 25.55  ? 61  ARG D NH2 1 
ATOM   2922 N N   . GLN B 2 62  ? 151.384 157.645 112.539 1.00 5.51   ? 62  GLN D N   1 
ATOM   2923 C CA  . GLN B 2 62  ? 151.805 157.256 111.199 1.00 7.61   ? 62  GLN D CA  1 
ATOM   2924 C C   . GLN B 2 62  ? 152.559 158.420 110.578 1.00 14.37  ? 62  GLN D C   1 
ATOM   2925 O O   . GLN B 2 62  ? 151.971 159.472 110.314 1.00 23.34  ? 62  GLN D O   1 
ATOM   2926 C CB  . GLN B 2 62  ? 150.605 156.871 110.339 1.00 20.61  ? 62  GLN D CB  1 
ATOM   2927 C CG  . GLN B 2 62  ? 150.935 155.954 109.189 1.00 11.13  ? 62  GLN D CG  1 
ATOM   2928 C CD  . GLN B 2 62  ? 149.753 155.744 108.282 1.00 23.68  ? 62  GLN D CD  1 
ATOM   2929 O OE1 . GLN B 2 62  ? 148.610 155.740 108.731 1.00 23.34  ? 62  GLN D OE1 1 
ATOM   2930 N NE2 . GLN B 2 62  ? 150.018 155.573 106.996 1.00 34.90  ? 62  GLN D NE2 1 
ATOM   2931 N N   . ALA B 2 63  ? 153.855 158.237 110.350 1.00 15.83  ? 63  ALA D N   1 
ATOM   2932 C CA  . ALA B 2 63  ? 154.619 159.242 109.636 1.00 17.92  ? 63  ALA D CA  1 
ATOM   2933 C C   . ALA B 2 63  ? 154.104 159.346 108.202 1.00 25.99  ? 63  ALA D C   1 
ATOM   2934 O O   . ALA B 2 63  ? 153.635 158.356 107.633 1.00 36.53  ? 63  ALA D O   1 
ATOM   2935 C CB  . ALA B 2 63  ? 156.104 158.892 109.639 1.00 19.18  ? 63  ALA D CB  1 
ATOM   2936 N N   . PRO B 2 64  ? 154.157 160.534 107.601 1.00 32.17  ? 64  PRO D N   1 
ATOM   2937 C CA  . PRO B 2 64  ? 153.664 160.686 106.224 1.00 31.03  ? 64  PRO D CA  1 
ATOM   2938 C C   . PRO B 2 64  ? 154.394 159.755 105.268 1.00 29.16  ? 64  PRO D C   1 
ATOM   2939 O O   . PRO B 2 64  ? 155.606 159.859 105.071 1.00 30.96  ? 64  PRO D O   1 
ATOM   2940 C CB  . PRO B 2 64  ? 153.939 162.163 105.910 1.00 28.07  ? 64  PRO D CB  1 
ATOM   2941 C CG  . PRO B 2 64  ? 154.900 162.625 106.960 1.00 30.53  ? 64  PRO D CG  1 
ATOM   2942 C CD  . PRO B 2 64  ? 154.611 161.812 108.169 1.00 28.49  ? 64  PRO D CD  1 
ATOM   2943 N N   . GLY B 2 65  ? 153.641 158.827 104.683 1.00 32.33  ? 65  GLY D N   1 
ATOM   2944 C CA  . GLY B 2 65  ? 154.196 157.845 103.775 1.00 34.21  ? 65  GLY D CA  1 
ATOM   2945 C C   . GLY B 2 65  ? 154.813 156.628 104.426 1.00 38.42  ? 65  GLY D C   1 
ATOM   2946 O O   . GLY B 2 65  ? 155.400 155.803 103.719 1.00 40.72  ? 65  GLY D O   1 
ATOM   2947 N N   . LYS B 2 66  ? 154.696 156.481 105.740 1.00 26.22  ? 66  LYS D N   1 
ATOM   2948 C CA  . LYS B 2 66  ? 155.302 155.372 106.464 1.00 17.28  ? 66  LYS D CA  1 
ATOM   2949 C C   . LYS B 2 66  ? 154.211 154.517 107.105 1.00 27.61  ? 66  LYS D C   1 
ATOM   2950 O O   . LYS B 2 66  ? 153.017 154.731 106.891 1.00 31.74  ? 66  LYS D O   1 
ATOM   2951 C CB  . LYS B 2 66  ? 156.295 155.890 107.505 1.00 26.17  ? 66  LYS D CB  1 
ATOM   2952 C CG  . LYS B 2 66  ? 157.754 155.733 107.112 1.00 28.40  ? 66  LYS D CG  1 
ATOM   2953 C CD  . LYS B 2 66  ? 158.083 156.559 105.882 1.00 31.11  ? 66  LYS D CD  1 
ATOM   2954 C CE  . LYS B 2 66  ? 159.038 155.822 104.961 1.00 29.71  ? 66  LYS D CE  1 
ATOM   2955 N NZ  . LYS B 2 66  ? 159.043 156.407 103.592 1.00 30.62  ? 66  LYS D NZ  1 
ATOM   2956 N N   . GLY B 2 67  ? 154.637 153.533 107.899 1.00 27.70  ? 67  GLY D N   1 
ATOM   2957 C CA  . GLY B 2 67  ? 153.722 152.602 108.520 1.00 19.94  ? 67  GLY D CA  1 
ATOM   2958 C C   . GLY B 2 67  ? 153.328 153.004 109.929 1.00 22.54  ? 67  GLY D C   1 
ATOM   2959 O O   . GLY B 2 67  ? 153.806 153.987 110.491 1.00 23.35  ? 67  GLY D O   1 
ATOM   2960 N N   . LEU B 2 68  ? 152.434 152.207 110.504 1.00 21.59  ? 68  LEU D N   1 
ATOM   2961 C CA  . LEU B 2 68  ? 151.933 152.467 111.844 1.00 1.59   ? 68  LEU D CA  1 
ATOM   2962 C C   . LEU B 2 68  ? 153.012 152.225 112.891 1.00 4.41   ? 68  LEU D C   1 
ATOM   2963 O O   . LEU B 2 68  ? 153.889 151.375 112.729 1.00 28.44  ? 68  LEU D O   1 
ATOM   2964 C CB  . LEU B 2 68  ? 150.723 151.586 112.137 1.00 0.00   ? 68  LEU D CB  1 
ATOM   2965 C CG  . LEU B 2 68  ? 149.546 151.760 111.187 1.00 1.54   ? 68  LEU D CG  1 
ATOM   2966 C CD1 . LEU B 2 68  ? 148.441 150.792 111.535 1.00 8.48   ? 68  LEU D CD1 1 
ATOM   2967 C CD2 . LEU B 2 68  ? 149.050 153.187 111.246 1.00 16.05  ? 68  LEU D CD2 1 
ATOM   2968 N N   . GLU B 2 69  ? 152.941 152.990 113.976 1.00 4.92   ? 69  GLU D N   1 
ATOM   2969 C CA  . GLU B 2 69  ? 153.864 152.820 115.092 1.00 2.44   ? 69  GLU D CA  1 
ATOM   2970 C C   . GLU B 2 69  ? 153.137 153.158 116.381 1.00 4.46   ? 69  GLU D C   1 
ATOM   2971 O O   . GLU B 2 69  ? 152.674 154.288 116.555 1.00 14.87  ? 69  GLU D O   1 
ATOM   2972 C CB  . GLU B 2 69  ? 155.103 153.698 114.929 1.00 11.92  ? 69  GLU D CB  1 
ATOM   2973 C CG  . GLU B 2 69  ? 156.339 153.122 115.590 1.00 13.91  ? 69  GLU D CG  1 
ATOM   2974 C CD  . GLU B 2 69  ? 157.276 154.187 116.119 1.00 34.73  ? 69  GLU D CD  1 
ATOM   2975 O OE1 . GLU B 2 69  ? 157.915 154.880 115.301 1.00 32.89  ? 69  GLU D OE1 1 
ATOM   2976 O OE2 . GLU B 2 69  ? 157.376 154.329 117.355 1.00 39.02  ? 69  GLU D OE2 1 
ATOM   2977 N N   . TRP B 2 70  ? 153.033 152.178 117.271 1.00 14.44  ? 70  TRP D N   1 
ATOM   2978 C CA  . TRP B 2 70  ? 152.446 152.405 118.582 1.00 12.06  ? 70  TRP D CA  1 
ATOM   2979 C C   . TRP B 2 70  ? 153.385 153.247 119.437 1.00 16.48  ? 70  TRP D C   1 
ATOM   2980 O O   . TRP B 2 70  ? 154.599 153.035 119.448 1.00 21.09  ? 70  TRP D O   1 
ATOM   2981 C CB  . TRP B 2 70  ? 152.157 151.065 119.257 1.00 10.52  ? 70  TRP D CB  1 
ATOM   2982 C CG  . TRP B 2 70  ? 151.889 151.141 120.719 1.00 0.00   ? 70  TRP D CG  1 
ATOM   2983 C CD1 . TRP B 2 70  ? 150.691 151.361 121.318 1.00 7.29   ? 70  TRP D CD1 1 
ATOM   2984 C CD2 . TRP B 2 70  ? 152.843 150.984 121.773 1.00 6.86   ? 70  TRP D CD2 1 
ATOM   2985 N NE1 . TRP B 2 70  ? 150.835 151.355 122.680 1.00 15.80  ? 70  TRP D NE1 1 
ATOM   2986 C CE2 . TRP B 2 70  ? 152.150 151.126 122.986 1.00 11.74  ? 70  TRP D CE2 1 
ATOM   2987 C CE3 . TRP B 2 70  ? 154.218 150.745 121.808 1.00 5.40   ? 70  TRP D CE3 1 
ATOM   2988 C CZ2 . TRP B 2 70  ? 152.781 151.034 124.219 1.00 3.12   ? 70  TRP D CZ2 1 
ATOM   2989 C CZ3 . TRP B 2 70  ? 154.841 150.655 123.030 1.00 12.36  ? 70  TRP D CZ3 1 
ATOM   2990 C CH2 . TRP B 2 70  ? 154.124 150.797 124.219 1.00 12.42  ? 70  TRP D CH2 1 
ATOM   2991 N N   . VAL B 2 71  ? 152.815 154.208 120.157 1.00 7.22   ? 71  VAL D N   1 
ATOM   2992 C CA  . VAL B 2 71  ? 153.580 155.191 120.912 1.00 1.31   ? 71  VAL D CA  1 
ATOM   2993 C C   . VAL B 2 71  ? 153.405 155.004 122.415 1.00 9.11   ? 71  VAL D C   1 
ATOM   2994 O O   . VAL B 2 71  ? 154.383 154.886 123.151 1.00 15.90  ? 71  VAL D O   1 
ATOM   2995 C CB  . VAL B 2 71  ? 153.204 156.626 120.484 1.00 8.87   ? 71  VAL D CB  1 
ATOM   2996 C CG1 . VAL B 2 71  ? 153.978 157.633 121.290 1.00 10.80  ? 71  VAL D CG1 1 
ATOM   2997 C CG2 . VAL B 2 71  ? 153.466 156.820 119.008 1.00 10.23  ? 71  VAL D CG2 1 
ATOM   2998 N N   . ALA B 2 72  ? 152.163 154.983 122.889 1.00 12.52  ? 72  ALA D N   1 
ATOM   2999 C CA  . ALA B 2 72  ? 151.909 154.881 124.316 1.00 0.00   ? 72  ALA D CA  1 
ATOM   3000 C C   . ALA B 2 72  ? 150.569 154.201 124.548 1.00 8.39   ? 72  ALA D C   1 
ATOM   3001 O O   . ALA B 2 72  ? 149.743 154.088 123.641 1.00 8.79   ? 72  ALA D O   1 
ATOM   3002 C CB  . ALA B 2 72  ? 151.932 156.254 124.990 1.00 8.50   ? 72  ALA D CB  1 
ATOM   3003 N N   . SER B 2 73  ? 150.370 153.740 125.781 1.00 21.76  ? 73  SER D N   1 
ATOM   3004 C CA  . SER B 2 73  ? 149.122 153.112 126.184 1.00 3.94   ? 73  SER D CA  1 
ATOM   3005 C C   . SER B 2 73  ? 148.952 153.255 127.688 1.00 12.46  ? 73  SER D C   1 
ATOM   3006 O O   . SER B 2 73  ? 149.929 153.264 128.439 1.00 17.61  ? 73  SER D O   1 
ATOM   3007 C CB  . SER B 2 73  ? 149.076 151.635 125.787 1.00 8.18   ? 73  SER D CB  1 
ATOM   3008 O OG  . SER B 2 73  ? 150.226 150.944 126.234 1.00 23.37  ? 73  SER D OG  1 
ATOM   3009 N N   . ILE B 2 74  ? 147.697 153.363 128.120 1.00 21.31  ? 74  ILE D N   1 
ATOM   3010 C CA  . ILE B 2 74  ? 147.356 153.526 129.528 1.00 15.51  ? 74  ILE D CA  1 
ATOM   3011 C C   . ILE B 2 74  ? 146.239 152.550 129.875 1.00 9.85   ? 74  ILE D C   1 
ATOM   3012 O O   . ILE B 2 74  ? 145.272 152.409 129.119 1.00 6.37   ? 74  ILE D O   1 
ATOM   3013 C CB  . ILE B 2 74  ? 146.952 154.980 129.854 1.00 5.69   ? 74  ILE D CB  1 
ATOM   3014 C CG1 . ILE B 2 74  ? 146.646 155.137 131.342 1.00 9.96   ? 74  ILE D CG1 1 
ATOM   3015 C CG2 . ILE B 2 74  ? 145.786 155.444 128.996 1.00 2.85   ? 74  ILE D CG2 1 
ATOM   3016 C CD1 . ILE B 2 74  ? 146.670 156.560 131.815 1.00 12.03  ? 74  ILE D CD1 1 
ATOM   3017 N N   . SER B 2 75  ? 146.379 151.866 131.009 1.00 9.12   ? 75  SER D N   1 
ATOM   3018 C CA  . SER B 2 75  ? 145.419 150.845 131.411 1.00 7.13   ? 75  SER D CA  1 
ATOM   3019 C C   . SER B 2 75  ? 144.249 151.425 132.196 1.00 17.72  ? 75  SER D C   1 
ATOM   3020 O O   . SER B 2 75  ? 143.090 151.116 131.898 1.00 33.44  ? 75  SER D O   1 
ATOM   3021 C CB  . SER B 2 75  ? 146.114 149.768 132.240 1.00 4.69   ? 75  SER D CB  1 
ATOM   3022 O OG  . SER B 2 75  ? 145.180 148.796 132.664 1.00 24.37  ? 75  SER D OG  1 
ATOM   3023 N N   . SER B 2 76  ? 144.545 152.218 133.227 1.00 11.05  ? 76  SER D N   1 
ATOM   3024 C CA  . SER B 2 76  ? 143.559 152.940 134.028 1.00 7.50   ? 76  SER D CA  1 
ATOM   3025 C C   . SER B 2 76  ? 142.759 152.011 134.934 1.00 0.45   ? 76  SER D C   1 
ATOM   3026 O O   . SER B 2 76  ? 142.017 152.479 135.800 1.00 5.60   ? 76  SER D O   1 
ATOM   3027 C CB  . SER B 2 76  ? 142.621 153.752 133.133 1.00 0.00   ? 76  SER D CB  1 
ATOM   3028 O OG  . SER B 2 76  ? 141.662 154.451 133.901 1.00 18.92  ? 76  SER D OG  1 
ATOM   3029 N N   . TYR B 2 77  ? 142.918 150.699 134.769 1.00 9.37   ? 77  TYR D N   1 
ATOM   3030 C CA  . TYR B 2 77  ? 142.386 149.723 135.711 1.00 0.00   ? 77  TYR D CA  1 
ATOM   3031 C C   . TYR B 2 77  ? 143.476 149.189 136.625 1.00 2.58   ? 77  TYR D C   1 
ATOM   3032 O O   . TYR B 2 77  ? 143.298 149.140 137.844 1.00 15.96  ? 77  TYR D O   1 
ATOM   3033 C CB  . TYR B 2 77  ? 141.712 148.561 134.968 1.00 7.81   ? 77  TYR D CB  1 
ATOM   3034 C CG  . TYR B 2 77  ? 140.956 147.600 135.867 1.00 7.53   ? 77  TYR D CG  1 
ATOM   3035 C CD1 . TYR B 2 77  ? 141.619 146.608 136.575 1.00 11.66  ? 77  TYR D CD1 1 
ATOM   3036 C CD2 . TYR B 2 77  ? 139.582 147.679 135.996 1.00 0.00   ? 77  TYR D CD2 1 
ATOM   3037 C CE1 . TYR B 2 77  ? 140.940 145.739 137.392 1.00 0.00   ? 77  TYR D CE1 1 
ATOM   3038 C CE2 . TYR B 2 77  ? 138.897 146.809 136.810 1.00 1.92   ? 77  TYR D CE2 1 
ATOM   3039 C CZ  . TYR B 2 77  ? 139.581 145.841 137.507 1.00 1.15   ? 77  TYR D CZ  1 
ATOM   3040 O OH  . TYR B 2 77  ? 138.899 144.970 138.321 1.00 12.55  ? 77  TYR D OH  1 
ATOM   3041 N N   . TYR B 2 78  ? 144.602 148.783 136.053 1.00 7.14   ? 78  TYR D N   1 
ATOM   3042 C CA  . TYR B 2 78  ? 145.765 148.368 136.817 1.00 13.79  ? 78  TYR D CA  1 
ATOM   3043 C C   . TYR B 2 78  ? 146.752 149.501 137.047 1.00 22.96  ? 78  TYR D C   1 
ATOM   3044 O O   . TYR B 2 78  ? 147.753 149.298 137.741 1.00 39.15  ? 78  TYR D O   1 
ATOM   3045 C CB  . TYR B 2 78  ? 146.473 147.213 136.110 1.00 9.14   ? 78  TYR D CB  1 
ATOM   3046 C CG  . TYR B 2 78  ? 145.587 146.029 135.822 1.00 16.71  ? 78  TYR D CG  1 
ATOM   3047 C CD1 . TYR B 2 78  ? 145.212 145.157 136.833 1.00 20.83  ? 78  TYR D CD1 1 
ATOM   3048 C CD2 . TYR B 2 78  ? 145.130 145.778 134.541 1.00 4.26   ? 78  TYR D CD2 1 
ATOM   3049 C CE1 . TYR B 2 78  ? 144.405 144.075 136.574 1.00 12.43  ? 78  TYR D CE1 1 
ATOM   3050 C CE2 . TYR B 2 78  ? 144.323 144.700 134.276 1.00 14.82  ? 78  TYR D CE2 1 
ATOM   3051 C CZ  . TYR B 2 78  ? 143.965 143.851 135.294 1.00 14.56  ? 78  TYR D CZ  1 
ATOM   3052 O OH  . TYR B 2 78  ? 143.159 142.772 135.025 1.00 34.34  ? 78  TYR D OH  1 
ATOM   3053 N N   . GLY B 2 79  ? 146.494 150.682 136.497 1.00 10.46  ? 79  GLY D N   1 
ATOM   3054 C CA  . GLY B 2 79  ? 147.418 151.793 136.630 1.00 9.49   ? 79  GLY D CA  1 
ATOM   3055 C C   . GLY B 2 79  ? 148.732 151.620 135.900 1.00 16.59  ? 79  GLY D C   1 
ATOM   3056 O O   . GLY B 2 79  ? 149.787 151.965 136.444 1.00 27.96  ? 79  GLY D O   1 
ATOM   3057 N N   . TYR B 2 80  ? 148.699 151.085 134.683 1.00 21.32  ? 80  TYR D N   1 
ATOM   3058 C CA  . TYR B 2 80  ? 149.879 150.982 133.836 1.00 12.57  ? 80  TYR D CA  1 
ATOM   3059 C C   . TYR B 2 80  ? 149.927 152.144 132.857 1.00 20.43  ? 80  TYR D C   1 
ATOM   3060 O O   . TYR B 2 80  ? 148.897 152.568 132.330 1.00 31.40  ? 80  TYR D O   1 
ATOM   3061 C CB  . TYR B 2 80  ? 149.896 149.683 133.029 1.00 21.80  ? 80  TYR D CB  1 
ATOM   3062 C CG  . TYR B 2 80  ? 149.746 148.396 133.799 1.00 29.04  ? 80  TYR D CG  1 
ATOM   3063 C CD1 . TYR B 2 80  ? 150.079 148.312 135.144 1.00 24.05  ? 80  TYR D CD1 1 
ATOM   3064 C CD2 . TYR B 2 80  ? 149.282 147.252 133.164 1.00 23.30  ? 80  TYR D CD2 1 
ATOM   3065 C CE1 . TYR B 2 80  ? 149.946 147.124 135.834 1.00 21.52  ? 80  TYR D CE1 1 
ATOM   3066 C CE2 . TYR B 2 80  ? 149.146 146.065 133.841 1.00 24.40  ? 80  TYR D CE2 1 
ATOM   3067 C CZ  . TYR B 2 80  ? 149.478 146.005 135.174 1.00 26.50  ? 80  TYR D CZ  1 
ATOM   3068 O OH  . TYR B 2 80  ? 149.336 144.816 135.842 1.00 35.82  ? 80  TYR D OH  1 
ATOM   3069 N N   . THR B 2 81  ? 151.130 152.653 132.618 1.00 20.24  ? 81  THR D N   1 
ATOM   3070 C CA  . THR B 2 81  ? 151.403 153.510 131.474 1.00 15.04  ? 81  THR D CA  1 
ATOM   3071 C C   . THR B 2 81  ? 152.612 152.944 130.750 1.00 18.77  ? 81  THR D C   1 
ATOM   3072 O O   . THR B 2 81  ? 153.631 152.646 131.380 1.00 20.08  ? 81  THR D O   1 
ATOM   3073 C CB  . THR B 2 81  ? 151.660 154.964 131.876 1.00 12.26  ? 81  THR D CB  1 
ATOM   3074 O OG1 . THR B 2 81  ? 153.013 155.105 132.323 1.00 35.74  ? 81  THR D OG1 1 
ATOM   3075 C CG2 . THR B 2 81  ? 150.711 155.404 132.971 1.00 10.13  ? 81  THR D CG2 1 
ATOM   3076 N N   . TYR B 2 82  ? 152.492 152.778 129.439 1.00 11.82  ? 82  TYR D N   1 
ATOM   3077 C CA  . TYR B 2 82  ? 153.548 152.210 128.621 1.00 4.52   ? 82  TYR D CA  1 
ATOM   3078 C C   . TYR B 2 82  ? 153.952 153.205 127.547 1.00 9.55   ? 82  TYR D C   1 
ATOM   3079 O O   . TYR B 2 82  ? 153.123 153.961 127.040 1.00 17.73  ? 82  TYR D O   1 
ATOM   3080 C CB  . TYR B 2 82  ? 153.104 150.895 127.979 1.00 15.11  ? 82  TYR D CB  1 
ATOM   3081 C CG  . TYR B 2 82  ? 152.848 149.797 128.980 1.00 21.18  ? 82  TYR D CG  1 
ATOM   3082 C CD1 . TYR B 2 82  ? 153.888 149.240 129.702 1.00 27.56  ? 82  TYR D CD1 1 
ATOM   3083 C CD2 . TYR B 2 82  ? 151.567 149.323 129.207 1.00 14.47  ? 82  TYR D CD2 1 
ATOM   3084 C CE1 . TYR B 2 82  ? 153.662 148.240 130.622 1.00 29.90  ? 82  TYR D CE1 1 
ATOM   3085 C CE2 . TYR B 2 82  ? 151.332 148.323 130.124 1.00 20.15  ? 82  TYR D CE2 1 
ATOM   3086 C CZ  . TYR B 2 82  ? 152.383 147.784 130.828 1.00 23.51  ? 82  TYR D CZ  1 
ATOM   3087 O OH  . TYR B 2 82  ? 152.159 146.786 131.745 1.00 23.05  ? 82  TYR D OH  1 
ATOM   3088 N N   . TYR B 2 83  ? 155.238 153.206 127.211 1.00 6.60   ? 83  TYR D N   1 
ATOM   3089 C CA  . TYR B 2 83  ? 155.774 154.126 126.221 1.00 7.10   ? 83  TYR D CA  1 
ATOM   3090 C C   . TYR B 2 83  ? 156.718 153.379 125.296 1.00 22.03  ? 83  TYR D C   1 
ATOM   3091 O O   . TYR B 2 83  ? 157.305 152.362 125.671 1.00 32.06  ? 83  TYR D O   1 
ATOM   3092 C CB  . TYR B 2 83  ? 156.502 155.303 126.884 1.00 16.60  ? 83  TYR D CB  1 
ATOM   3093 C CG  . TYR B 2 83  ? 155.665 156.010 127.921 1.00 19.33  ? 83  TYR D CG  1 
ATOM   3094 C CD1 . TYR B 2 83  ? 154.696 156.926 127.549 1.00 13.79  ? 83  TYR D CD1 1 
ATOM   3095 C CD2 . TYR B 2 83  ? 155.826 155.745 129.268 1.00 17.92  ? 83  TYR D CD2 1 
ATOM   3096 C CE1 . TYR B 2 83  ? 153.922 157.561 128.488 1.00 8.68   ? 83  TYR D CE1 1 
ATOM   3097 C CE2 . TYR B 2 83  ? 155.054 156.378 130.213 1.00 12.67  ? 83  TYR D CE2 1 
ATOM   3098 C CZ  . TYR B 2 83  ? 154.105 157.284 129.819 1.00 12.38  ? 83  TYR D CZ  1 
ATOM   3099 O OH  . TYR B 2 83  ? 153.338 157.918 130.766 1.00 19.39  ? 83  TYR D OH  1 
ATOM   3100 N N   . ALA B 2 84  ? 156.857 153.895 124.080 1.00 18.22  ? 84  ALA D N   1 
ATOM   3101 C CA  . ALA B 2 84  ? 157.789 153.312 123.135 1.00 3.93   ? 84  ALA D CA  1 
ATOM   3102 C C   . ALA B 2 84  ? 159.225 153.583 123.574 1.00 24.44  ? 84  ALA D C   1 
ATOM   3103 O O   . ALA B 2 84  ? 159.496 154.439 124.417 1.00 40.04  ? 84  ALA D O   1 
ATOM   3104 C CB  . ALA B 2 84  ? 157.549 153.869 121.734 1.00 17.30  ? 84  ALA D CB  1 
ATOM   3105 N N   . ASP B 2 85  ? 160.155 152.834 122.986 1.00 35.54  ? 85  ASP D N   1 
ATOM   3106 C CA  . ASP B 2 85  ? 161.562 153.005 123.320 1.00 33.51  ? 85  ASP D CA  1 
ATOM   3107 C C   . ASP B 2 85  ? 162.137 154.310 122.790 1.00 35.75  ? 85  ASP D C   1 
ATOM   3108 O O   . ASP B 2 85  ? 163.275 154.647 123.130 1.00 42.94  ? 85  ASP D O   1 
ATOM   3109 C CB  . ASP B 2 85  ? 162.377 151.828 122.786 1.00 34.07  ? 85  ASP D CB  1 
ATOM   3110 N N   . SER B 2 86  ? 161.390 155.041 121.965 1.00 33.43  ? 86  SER D N   1 
ATOM   3111 C CA  . SER B 2 86  ? 161.853 156.299 121.402 1.00 33.69  ? 86  SER D CA  1 
ATOM   3112 C C   . SER B 2 86  ? 161.175 157.520 122.008 1.00 35.94  ? 86  SER D C   1 
ATOM   3113 O O   . SER B 2 86  ? 161.629 158.642 121.763 1.00 40.45  ? 86  SER D O   1 
ATOM   3114 C CB  . SER B 2 86  ? 161.637 156.306 119.884 1.00 32.64  ? 86  SER D CB  1 
ATOM   3115 O OG  . SER B 2 86  ? 160.324 156.725 119.561 1.00 36.69  ? 86  SER D OG  1 
ATOM   3116 N N   . VAL B 2 87  ? 160.110 157.337 122.786 1.00 32.95  ? 87  VAL D N   1 
ATOM   3117 C CA  . VAL B 2 87  ? 159.351 158.457 123.330 1.00 27.74  ? 87  VAL D CA  1 
ATOM   3118 C C   . VAL B 2 87  ? 159.235 158.339 124.843 1.00 32.75  ? 87  VAL D C   1 
ATOM   3119 O O   . VAL B 2 87  ? 158.489 159.096 125.473 1.00 40.42  ? 87  VAL D O   1 
ATOM   3120 C CB  . VAL B 2 87  ? 157.952 158.536 122.695 1.00 23.26  ? 87  VAL D CB  1 
ATOM   3121 C CG1 . VAL B 2 87  ? 158.047 158.504 121.183 1.00 29.00  ? 87  VAL D CG1 1 
ATOM   3122 C CG2 . VAL B 2 87  ? 157.082 157.400 123.202 1.00 21.80  ? 87  VAL D CG2 1 
ATOM   3123 N N   . LYS B 2 88  ? 159.981 157.406 125.438 1.00 28.05  ? 88  LYS D N   1 
ATOM   3124 C CA  . LYS B 2 88  ? 159.753 157.056 126.837 1.00 26.16  ? 88  LYS D CA  1 
ATOM   3125 C C   . LYS B 2 88  ? 159.941 158.258 127.755 1.00 33.53  ? 88  LYS D C   1 
ATOM   3126 O O   . LYS B 2 88  ? 159.060 158.582 128.559 1.00 33.17  ? 88  LYS D O   1 
ATOM   3127 C CB  . LYS B 2 88  ? 160.683 155.914 127.248 1.00 28.51  ? 88  LYS D CB  1 
ATOM   3128 C CG  . LYS B 2 88  ? 160.281 155.233 128.547 1.00 30.82  ? 88  LYS D CG  1 
ATOM   3129 C CD  . LYS B 2 88  ? 160.746 153.787 128.592 1.00 32.42  ? 88  LYS D CD  1 
ATOM   3130 C CE  . LYS B 2 88  ? 159.873 152.896 127.722 1.00 29.85  ? 88  LYS D CE  1 
ATOM   3131 N NZ  . LYS B 2 88  ? 159.057 151.950 128.534 1.00 33.07  ? 88  LYS D NZ  1 
ATOM   3132 N N   . GLY B 2 89  ? 161.084 158.935 127.648 1.00 34.89  ? 89  GLY D N   1 
ATOM   3133 C CA  . GLY B 2 89  ? 161.340 160.068 128.523 1.00 30.79  ? 89  GLY D CA  1 
ATOM   3134 C C   . GLY B 2 89  ? 160.452 161.262 128.230 1.00 35.29  ? 89  GLY D C   1 
ATOM   3135 O O   . GLY B 2 89  ? 159.978 161.935 129.149 1.00 35.40  ? 89  GLY D O   1 
ATOM   3136 N N   . ARG B 2 90  ? 160.204 161.535 126.951 1.00 35.43  ? 90  ARG D N   1 
ATOM   3137 C CA  . ARG B 2 90  ? 159.591 162.789 126.538 1.00 28.81  ? 90  ARG D CA  1 
ATOM   3138 C C   . ARG B 2 90  ? 158.070 162.741 126.503 1.00 36.16  ? 90  ARG D C   1 
ATOM   3139 O O   . ARG B 2 90  ? 157.420 163.737 126.842 1.00 35.63  ? 90  ARG D O   1 
ATOM   3140 C CB  . ARG B 2 90  ? 160.125 163.187 125.163 1.00 23.68  ? 90  ARG D CB  1 
ATOM   3141 C CG  . ARG B 2 90  ? 161.606 162.920 124.998 1.00 25.84  ? 90  ARG D CG  1 
ATOM   3142 C CD  . ARG B 2 90  ? 161.946 162.497 123.582 1.00 32.55  ? 90  ARG D CD  1 
ATOM   3143 N NE  . ARG B 2 90  ? 161.052 163.094 122.598 1.00 30.73  ? 90  ARG D NE  1 
ATOM   3144 C CZ  . ARG B 2 90  ? 160.631 162.483 121.500 1.00 34.05  ? 90  ARG D CZ  1 
ATOM   3145 N NH1 . ARG B 2 90  ? 160.985 161.239 121.223 1.00 33.79  ? 90  ARG D NH1 1 
ATOM   3146 N NH2 . ARG B 2 90  ? 159.841 163.137 120.656 1.00 34.17  ? 90  ARG D NH2 1 
ATOM   3147 N N   . PHE B 2 91  ? 157.484 161.621 126.095 1.00 26.74  ? 91  PHE D N   1 
ATOM   3148 C CA  . PHE B 2 91  ? 156.036 161.493 126.029 1.00 13.34  ? 91  PHE D CA  1 
ATOM   3149 C C   . PHE B 2 91  ? 155.516 160.961 127.355 1.00 17.61  ? 91  PHE D C   1 
ATOM   3150 O O   . PHE B 2 91  ? 156.118 160.066 127.953 1.00 20.74  ? 91  PHE D O   1 
ATOM   3151 C CB  . PHE B 2 91  ? 155.611 160.550 124.902 1.00 21.17  ? 91  PHE D CB  1 
ATOM   3152 C CG  . PHE B 2 91  ? 155.764 161.120 123.515 1.00 24.26  ? 91  PHE D CG  1 
ATOM   3153 C CD1 . PHE B 2 91  ? 156.810 161.965 123.195 1.00 33.01  ? 91  PHE D CD1 1 
ATOM   3154 C CD2 . PHE B 2 91  ? 154.870 160.776 122.519 1.00 23.59  ? 91  PHE D CD2 1 
ATOM   3155 C CE1 . PHE B 2 91  ? 156.950 162.467 121.917 1.00 25.43  ? 91  PHE D CE1 1 
ATOM   3156 C CE2 . PHE B 2 91  ? 155.008 161.271 121.240 1.00 27.20  ? 91  PHE D CE2 1 
ATOM   3157 C CZ  . PHE B 2 91  ? 156.052 162.114 120.939 1.00 25.18  ? 91  PHE D CZ  1 
ATOM   3158 N N   . THR B 2 92  ? 154.405 161.523 127.818 1.00 15.16  ? 92  THR D N   1 
ATOM   3159 C CA  . THR B 2 92  ? 153.737 161.039 129.017 1.00 16.67  ? 92  THR D CA  1 
ATOM   3160 C C   . THR B 2 92  ? 152.242 160.946 128.749 1.00 21.13  ? 92  THR D C   1 
ATOM   3161 O O   . THR B 2 92  ? 151.660 161.830 128.115 1.00 27.07  ? 92  THR D O   1 
ATOM   3162 C CB  . THR B 2 92  ? 154.031 161.942 130.235 1.00 28.37  ? 92  THR D CB  1 
ATOM   3163 O OG1 . THR B 2 92  ? 153.505 161.342 131.425 1.00 26.32  ? 92  THR D OG1 1 
ATOM   3164 C CG2 . THR B 2 92  ? 153.435 163.328 130.061 1.00 26.89  ? 92  THR D CG2 1 
ATOM   3165 N N   . ILE B 2 93  ? 151.627 159.862 129.215 1.00 22.68  ? 93  ILE D N   1 
ATOM   3166 C CA  . ILE B 2 93  ? 150.221 159.585 128.950 1.00 19.66  ? 93  ILE D CA  1 
ATOM   3167 C C   . ILE B 2 93  ? 149.459 159.590 130.266 1.00 17.14  ? 93  ILE D C   1 
ATOM   3168 O O   . ILE B 2 93  ? 149.982 159.173 131.305 1.00 24.87  ? 93  ILE D O   1 
ATOM   3169 C CB  . ILE B 2 93  ? 150.026 158.250 128.198 1.00 22.43  ? 93  ILE D CB  1 
ATOM   3170 C CG1 . ILE B 2 93  ? 148.576 158.106 127.729 1.00 21.90  ? 93  ILE D CG1 1 
ATOM   3171 C CG2 . ILE B 2 93  ? 150.439 157.066 129.053 1.00 18.31  ? 93  ILE D CG2 1 
ATOM   3172 C CD1 . ILE B 2 93  ? 148.350 156.950 126.797 1.00 10.06  ? 93  ILE D CD1 1 
ATOM   3173 N N   . SER B 2 94  ? 148.227 160.087 130.220 1.00 22.36  ? 94  SER D N   1 
ATOM   3174 C CA  . SER B 2 94  ? 147.379 160.177 131.397 1.00 20.17  ? 94  SER D CA  1 
ATOM   3175 C C   . SER B 2 94  ? 145.932 160.164 130.941 1.00 16.88  ? 94  SER D C   1 
ATOM   3176 O O   . SER B 2 94  ? 145.631 160.387 129.767 1.00 22.08  ? 94  SER D O   1 
ATOM   3177 C CB  . SER B 2 94  ? 147.673 161.438 132.212 1.00 25.92  ? 94  SER D CB  1 
ATOM   3178 O OG  . SER B 2 94  ? 147.080 162.579 131.617 1.00 25.15  ? 94  SER D OG  1 
ATOM   3179 N N   . ALA B 2 95  ? 145.039 159.900 131.885 1.00 17.61  ? 95  ALA D N   1 
ATOM   3180 C CA  . ALA B 2 95  ? 143.613 159.876 131.612 1.00 25.33  ? 95  ALA D CA  1 
ATOM   3181 C C   . ALA B 2 95  ? 142.876 160.701 132.654 1.00 31.53  ? 95  ALA D C   1 
ATOM   3182 O O   . ALA B 2 95  ? 143.293 160.788 133.811 1.00 35.25  ? 95  ALA D O   1 
ATOM   3183 C CB  . ALA B 2 95  ? 143.066 158.444 131.599 1.00 24.24  ? 95  ALA D CB  1 
ATOM   3184 N N   . ASP B 2 96  ? 141.784 161.319 132.226 1.00 40.88  ? 96  ASP D N   1 
ATOM   3185 C CA  . ASP B 2 96  ? 140.865 162.017 133.118 1.00 36.56  ? 96  ASP D CA  1 
ATOM   3186 C C   . ASP B 2 96  ? 139.597 161.176 133.182 1.00 39.74  ? 96  ASP D C   1 
ATOM   3187 O O   . ASP B 2 96  ? 138.815 161.140 132.228 1.00 39.52  ? 96  ASP D O   1 
ATOM   3188 C CB  . ASP B 2 96  ? 140.580 163.431 132.626 1.00 29.80  ? 96  ASP D CB  1 
ATOM   3189 C CG  . ASP B 2 96  ? 139.612 164.170 133.522 1.00 37.71  ? 96  ASP D CG  1 
ATOM   3190 O OD1 . ASP B 2 96  ? 140.071 164.829 134.476 1.00 42.23  ? 96  ASP D OD1 1 
ATOM   3191 O OD2 . ASP B 2 96  ? 138.393 164.087 133.277 1.00 44.56  ? 96  ASP D OD2 1 
ATOM   3192 N N   . THR B 2 97  ? 139.402 160.497 134.312 1.00 36.69  ? 97  THR D N   1 
ATOM   3193 C CA  . THR B 2 97  ? 138.290 159.562 134.433 1.00 32.55  ? 97  THR D CA  1 
ATOM   3194 C C   . THR B 2 97  ? 136.947 160.268 134.312 1.00 38.71  ? 97  THR D C   1 
ATOM   3195 O O   . THR B 2 97  ? 136.039 159.775 133.633 1.00 36.18  ? 97  THR D O   1 
ATOM   3196 C CB  . THR B 2 97  ? 138.386 158.817 135.762 1.00 39.86  ? 97  THR D CB  1 
ATOM   3197 O OG1 . THR B 2 97  ? 139.446 157.855 135.696 1.00 40.96  ? 97  THR D OG1 1 
ATOM   3198 C CG2 . THR B 2 97  ? 137.074 158.117 136.081 1.00 40.16  ? 97  THR D CG2 1 
ATOM   3199 N N   . SER B 2 98  ? 136.806 161.431 134.952 1.00 44.18  ? 98  SER D N   1 
ATOM   3200 C CA  . SER B 2 98  ? 135.511 162.103 135.003 1.00 40.01  ? 98  SER D CA  1 
ATOM   3201 C C   . SER B 2 98  ? 135.015 162.462 133.608 1.00 44.59  ? 98  SER D C   1 
ATOM   3202 O O   . SER B 2 98  ? 133.846 162.237 133.276 1.00 48.65  ? 98  SER D O   1 
ATOM   3203 C CB  . SER B 2 98  ? 135.607 163.351 135.879 1.00 44.79  ? 98  SER D CB  1 
ATOM   3204 O OG  . SER B 2 98  ? 134.444 164.150 135.761 1.00 50.80  ? 98  SER D OG  1 
ATOM   3205 N N   . LYS B 2 99  ? 135.891 163.014 132.774 1.00 39.15  ? 99  LYS D N   1 
ATOM   3206 C CA  . LYS B 2 99  ? 135.523 163.400 131.419 1.00 37.63  ? 99  LYS D CA  1 
ATOM   3207 C C   . LYS B 2 99  ? 135.801 162.309 130.395 1.00 40.04  ? 99  LYS D C   1 
ATOM   3208 O O   . LYS B 2 99  ? 135.562 162.528 129.204 1.00 43.36  ? 99  LYS D O   1 
ATOM   3209 C CB  . LYS B 2 99  ? 136.253 164.684 131.015 1.00 38.45  ? 99  LYS D CB  1 
ATOM   3210 N N   . ASN B 2 100 ? 136.296 161.149 130.830 1.00 37.69  ? 100 ASN D N   1 
ATOM   3211 C CA  . ASN B 2 100 ? 136.576 160.016 129.947 1.00 27.81  ? 100 ASN D CA  1 
ATOM   3212 C C   . ASN B 2 100 ? 137.486 160.436 128.796 1.00 28.25  ? 100 ASN D C   1 
ATOM   3213 O O   . ASN B 2 100 ? 137.256 160.106 127.632 1.00 42.71  ? 100 ASN D O   1 
ATOM   3214 C CB  . ASN B 2 100 ? 135.281 159.394 129.424 1.00 27.64  ? 100 ASN D CB  1 
ATOM   3215 C CG  . ASN B 2 100 ? 134.777 158.275 130.308 1.00 34.03  ? 100 ASN D CG  1 
ATOM   3216 O OD1 . ASN B 2 100 ? 135.536 157.391 130.705 1.00 38.32  ? 100 ASN D OD1 1 
ATOM   3217 N ND2 . ASN B 2 100 ? 133.489 158.303 130.619 1.00 38.68  ? 100 ASN D ND2 1 
ATOM   3218 N N   . THR B 2 101 ? 138.529 161.184 129.135 1.00 32.49  ? 101 THR D N   1 
ATOM   3219 C CA  . THR B 2 101 ? 139.442 161.751 128.156 1.00 31.62  ? 101 THR D CA  1 
ATOM   3220 C C   . THR B 2 101 ? 140.861 161.314 128.478 1.00 24.39  ? 101 THR D C   1 
ATOM   3221 O O   . THR B 2 101 ? 141.305 161.427 129.624 1.00 27.68  ? 101 THR D O   1 
ATOM   3222 C CB  . THR B 2 101 ? 139.348 163.280 128.140 1.00 31.07  ? 101 THR D CB  1 
ATOM   3223 O OG1 . THR B 2 101 ? 138.020 163.675 127.774 1.00 34.38  ? 101 THR D OG1 1 
ATOM   3224 C CG2 . THR B 2 101 ? 140.328 163.866 127.148 1.00 33.34  ? 101 THR D CG2 1 
ATOM   3225 N N   . ALA B 2 102 ? 141.565 160.815 127.470 1.00 26.57  ? 102 ALA D N   1 
ATOM   3226 C CA  . ALA B 2 102 ? 142.967 160.460 127.595 1.00 23.56  ? 102 ALA D CA  1 
ATOM   3227 C C   . ALA B 2 102 ? 143.831 161.581 127.041 1.00 25.86  ? 102 ALA D C   1 
ATOM   3228 O O   . ALA B 2 102 ? 143.462 162.257 126.079 1.00 32.70  ? 102 ALA D O   1 
ATOM   3229 C CB  . ALA B 2 102 ? 143.274 159.156 126.863 1.00 22.52  ? 102 ALA D CB  1 
ATOM   3230 N N   . TYR B 2 103 ? 144.985 161.776 127.663 1.00 32.58  ? 103 TYR D N   1 
ATOM   3231 C CA  . TYR B 2 103 ? 145.861 162.887 127.337 1.00 24.44  ? 103 TYR D CA  1 
ATOM   3232 C C   . TYR B 2 103 ? 147.247 162.356 127.011 1.00 25.83  ? 103 TYR D C   1 
ATOM   3233 O O   . TYR B 2 103 ? 147.726 161.416 127.649 1.00 35.36  ? 103 TYR D O   1 
ATOM   3234 C CB  . TYR B 2 103 ? 145.934 163.877 128.501 1.00 22.85  ? 103 TYR D CB  1 
ATOM   3235 C CG  . TYR B 2 103 ? 144.718 164.759 128.609 1.00 22.21  ? 103 TYR D CG  1 
ATOM   3236 C CD1 . TYR B 2 103 ? 144.356 165.602 127.573 1.00 26.18  ? 103 TYR D CD1 1 
ATOM   3237 C CD2 . TYR B 2 103 ? 143.918 164.730 129.738 1.00 22.34  ? 103 TYR D CD2 1 
ATOM   3238 C CE1 . TYR B 2 103 ? 143.239 166.402 127.665 1.00 28.95  ? 103 TYR D CE1 1 
ATOM   3239 C CE2 . TYR B 2 103 ? 142.799 165.524 129.840 1.00 26.18  ? 103 TYR D CE2 1 
ATOM   3240 C CZ  . TYR B 2 103 ? 142.465 166.360 128.800 1.00 31.92  ? 103 TYR D CZ  1 
ATOM   3241 O OH  . TYR B 2 103 ? 141.351 167.158 128.894 1.00 39.73  ? 103 TYR D OH  1 
ATOM   3242 N N   . LEU B 2 104 ? 147.881 162.955 126.010 1.00 11.84  ? 104 LEU D N   1 
ATOM   3243 C CA  . LEU B 2 104 ? 149.254 162.624 125.641 1.00 11.01  ? 104 LEU D CA  1 
ATOM   3244 C C   . LEU B 2 104 ? 150.028 163.933 125.566 1.00 20.69  ? 104 LEU D C   1 
ATOM   3245 O O   . LEU B 2 104 ? 149.919 164.671 124.584 1.00 22.49  ? 104 LEU D O   1 
ATOM   3246 C CB  . LEU B 2 104 ? 149.315 161.868 124.322 1.00 8.21   ? 104 LEU D CB  1 
ATOM   3247 C CG  . LEU B 2 104 ? 150.722 161.529 123.832 1.00 12.50  ? 104 LEU D CG  1 
ATOM   3248 C CD1 . LEU B 2 104 ? 151.314 160.386 124.638 1.00 2.05   ? 104 LEU D CD1 1 
ATOM   3249 C CD2 . LEU B 2 104 ? 150.712 161.204 122.352 1.00 20.02  ? 104 LEU D CD2 1 
ATOM   3250 N N   . GLN B 2 105 ? 150.802 164.221 126.605 1.00 19.57  ? 105 GLN D N   1 
ATOM   3251 C CA  . GLN B 2 105 ? 151.626 165.420 126.647 1.00 26.21  ? 105 GLN D CA  1 
ATOM   3252 C C   . GLN B 2 105 ? 152.954 165.109 125.972 1.00 28.35  ? 105 GLN D C   1 
ATOM   3253 O O   . GLN B 2 105 ? 153.723 164.273 126.454 1.00 30.43  ? 105 GLN D O   1 
ATOM   3254 C CB  . GLN B 2 105 ? 151.827 165.889 128.085 1.00 25.98  ? 105 GLN D CB  1 
ATOM   3255 C CG  . GLN B 2 105 ? 153.055 166.752 128.296 1.00 20.75  ? 105 GLN D CG  1 
ATOM   3256 C CD  . GLN B 2 105 ? 152.874 168.156 127.775 1.00 23.11  ? 105 GLN D CD  1 
ATOM   3257 O OE1 . GLN B 2 105 ? 151.771 168.697 127.789 1.00 27.28  ? 105 GLN D OE1 1 
ATOM   3258 N NE2 . GLN B 2 105 ? 153.962 168.758 127.314 1.00 24.95  ? 105 GLN D NE2 1 
ATOM   3259 N N   . MET B 2 106 ? 153.211 165.767 124.850 1.00 25.79  ? 106 MET D N   1 
ATOM   3260 C CA  . MET B 2 106 ? 154.477 165.635 124.152 1.00 22.18  ? 106 MET D CA  1 
ATOM   3261 C C   . MET B 2 106 ? 155.468 166.658 124.682 1.00 32.45  ? 106 MET D C   1 
ATOM   3262 O O   . MET B 2 106 ? 155.090 167.757 125.090 1.00 35.92  ? 106 MET D O   1 
ATOM   3263 C CB  . MET B 2 106 ? 154.295 165.836 122.651 1.00 28.93  ? 106 MET D CB  1 
ATOM   3264 C CG  . MET B 2 106 ? 154.081 164.561 121.881 1.00 28.59  ? 106 MET D CG  1 
ATOM   3265 S SD  . MET B 2 106 ? 153.231 164.810 120.318 1.00 37.24  ? 106 MET D SD  1 
ATOM   3266 C CE  . MET B 2 106 ? 151.551 164.799 120.896 1.00 29.50  ? 106 MET D CE  1 
ATOM   3267 N N   . ASN B 2 107 ? 156.745 166.289 124.671 1.00 25.75  ? 107 ASN D N   1 
ATOM   3268 C CA  . ASN B 2 107 ? 157.794 167.200 125.099 1.00 26.05  ? 107 ASN D CA  1 
ATOM   3269 C C   . ASN B 2 107 ? 159.045 166.920 124.283 1.00 31.20  ? 107 ASN D C   1 
ATOM   3270 O O   . ASN B 2 107 ? 159.235 165.817 123.766 1.00 41.78  ? 107 ASN D O   1 
ATOM   3271 C CB  . ASN B 2 107 ? 158.088 167.063 126.598 1.00 29.35  ? 107 ASN D CB  1 
ATOM   3272 C CG  . ASN B 2 107 ? 157.062 167.766 127.465 1.00 32.45  ? 107 ASN D CG  1 
ATOM   3273 O OD1 . ASN B 2 107 ? 156.614 168.868 127.154 1.00 33.73  ? 107 ASN D OD1 1 
ATOM   3274 N ND2 . ASN B 2 107 ? 156.687 167.129 128.565 1.00 29.16  ? 107 ASN D ND2 1 
ATOM   3275 N N   . SER B 2 108 ? 159.897 167.939 124.171 1.00 27.54  ? 108 SER D N   1 
ATOM   3276 C CA  . SER B 2 108 ? 161.173 167.833 123.466 1.00 24.89  ? 108 SER D CA  1 
ATOM   3277 C C   . SER B 2 108 ? 160.979 167.274 122.060 1.00 34.01  ? 108 SER D C   1 
ATOM   3278 O O   . SER B 2 108 ? 161.685 166.367 121.617 1.00 34.96  ? 108 SER D O   1 
ATOM   3279 C CB  . SER B 2 108 ? 162.163 166.985 124.261 1.00 30.13  ? 108 SER D CB  1 
ATOM   3280 O OG  . SER B 2 108 ? 162.186 167.380 125.619 1.00 39.62  ? 108 SER D OG  1 
ATOM   3281 N N   . LEU B 2 109 ? 159.999 167.829 121.355 1.00 39.18  ? 109 LEU D N   1 
ATOM   3282 C CA  . LEU B 2 109 ? 159.624 167.313 120.048 1.00 28.52  ? 109 LEU D CA  1 
ATOM   3283 C C   . LEU B 2 109 ? 160.721 167.580 119.029 1.00 30.73  ? 109 LEU D C   1 
ATOM   3284 O O   . LEU B 2 109 ? 161.224 168.701 118.923 1.00 39.98  ? 109 LEU D O   1 
ATOM   3285 C CB  . LEU B 2 109 ? 158.313 167.948 119.596 1.00 20.72  ? 109 LEU D CB  1 
ATOM   3286 C CG  . LEU B 2 109 ? 157.110 167.458 120.396 1.00 18.62  ? 109 LEU D CG  1 
ATOM   3287 C CD1 . LEU B 2 109 ? 155.848 168.143 119.949 1.00 24.66  ? 109 LEU D CD1 1 
ATOM   3288 C CD2 . LEU B 2 109 ? 156.986 165.961 120.255 1.00 26.44  ? 109 LEU D CD2 1 
ATOM   3289 N N   . ARG B 2 110 ? 161.085 166.551 118.275 1.00 34.26  ? 110 ARG D N   1 
ATOM   3290 C CA  . ARG B 2 110 ? 162.114 166.637 117.252 1.00 37.14  ? 110 ARG D CA  1 
ATOM   3291 C C   . ARG B 2 110 ? 161.477 166.561 115.870 1.00 38.27  ? 110 ARG D C   1 
ATOM   3292 O O   . ARG B 2 110 ? 160.254 166.540 115.720 1.00 39.83  ? 110 ARG D O   1 
ATOM   3293 C CB  . ARG B 2 110 ? 163.154 165.531 117.433 1.00 36.12  ? 110 ARG D CB  1 
ATOM   3294 C CG  . ARG B 2 110 ? 163.409 165.135 118.872 1.00 40.89  ? 110 ARG D CG  1 
ATOM   3295 C CD  . ARG B 2 110 ? 164.623 164.228 118.969 1.00 43.01  ? 110 ARG D CD  1 
ATOM   3296 N NE  . ARG B 2 110 ? 164.731 163.591 120.275 1.00 44.69  ? 110 ARG D NE  1 
ATOM   3297 C CZ  . ARG B 2 110 ? 164.515 162.302 120.496 1.00 41.61  ? 110 ARG D CZ  1 
ATOM   3298 N NH1 . ARG B 2 110 ? 164.176 161.480 119.516 1.00 38.84  ? 110 ARG D NH1 1 
ATOM   3299 N NH2 . ARG B 2 110 ? 164.641 161.826 121.731 1.00 36.50  ? 110 ARG D NH2 1 
ATOM   3300 N N   . ALA B 2 111 ? 162.334 166.528 114.848 1.00 45.34  ? 111 ALA D N   1 
ATOM   3301 C CA  . ALA B 2 111 ? 161.849 166.408 113.479 1.00 38.18  ? 111 ALA D CA  1 
ATOM   3302 C C   . ALA B 2 111 ? 161.191 165.058 113.232 1.00 40.50  ? 111 ALA D C   1 
ATOM   3303 O O   . ALA B 2 111 ? 160.211 164.976 112.482 1.00 40.62  ? 111 ALA D O   1 
ATOM   3304 C CB  . ALA B 2 111 ? 162.995 166.631 112.493 1.00 40.08  ? 111 ALA D CB  1 
ATOM   3305 N N   . GLU B 2 112 ? 161.703 163.994 113.852 1.00 41.45  ? 112 GLU D N   1 
ATOM   3306 C CA  . GLU B 2 112 ? 161.125 162.667 113.679 1.00 40.48  ? 112 GLU D CA  1 
ATOM   3307 C C   . GLU B 2 112 ? 159.919 162.482 114.590 1.00 38.54  ? 112 GLU D C   1 
ATOM   3308 O O   . GLU B 2 112 ? 159.797 161.466 115.281 1.00 39.49  ? 112 GLU D O   1 
ATOM   3309 C CB  . GLU B 2 112 ? 162.171 161.587 113.957 1.00 40.91  ? 112 GLU D CB  1 
ATOM   3310 C CG  . GLU B 2 112 ? 163.118 161.920 115.091 1.00 45.65  ? 112 GLU D CG  1 
ATOM   3311 C CD  . GLU B 2 112 ? 164.432 162.496 114.603 1.00 51.90  ? 112 GLU D CD  1 
ATOM   3312 O OE1 . GLU B 2 112 ? 164.440 163.132 113.528 1.00 48.46  ? 112 GLU D OE1 1 
ATOM   3313 O OE2 . GLU B 2 112 ? 165.456 162.315 115.294 1.00 53.18  ? 112 GLU D OE2 1 
ATOM   3314 N N   . ASP B 2 113 ? 159.023 163.462 114.588 1.00 33.22  ? 113 ASP D N   1 
ATOM   3315 C CA  . ASP B 2 113 ? 157.764 163.364 115.306 1.00 27.23  ? 113 ASP D CA  1 
ATOM   3316 C C   . ASP B 2 113 ? 156.599 163.866 114.471 1.00 30.64  ? 113 ASP D C   1 
ATOM   3317 O O   . ASP B 2 113 ? 155.463 163.843 114.952 1.00 27.46  ? 113 ASP D O   1 
ATOM   3318 C CB  . ASP B 2 113 ? 157.824 164.143 116.627 1.00 31.69  ? 113 ASP D CB  1 
ATOM   3319 C CG  . ASP B 2 113 ? 158.903 163.629 117.558 1.00 35.90  ? 113 ASP D CG  1 
ATOM   3320 O OD1 . ASP B 2 113 ? 158.902 162.420 117.862 1.00 30.10  ? 113 ASP D OD1 1 
ATOM   3321 O OD2 . ASP B 2 113 ? 159.755 164.434 117.985 1.00 42.70  ? 113 ASP D OD2 1 
ATOM   3322 N N   . THR B 2 114 ? 156.847 164.326 113.246 1.00 23.10  ? 114 THR D N   1 
ATOM   3323 C CA  . THR B 2 114 ? 155.788 164.670 112.310 1.00 13.51  ? 114 THR D CA  1 
ATOM   3324 C C   . THR B 2 114 ? 155.028 163.410 111.925 1.00 24.85  ? 114 THR D C   1 
ATOM   3325 O O   . THR B 2 114 ? 155.583 162.521 111.273 1.00 34.99  ? 114 THR D O   1 
ATOM   3326 C CB  . THR B 2 114 ? 156.362 165.343 111.064 1.00 23.11  ? 114 THR D CB  1 
ATOM   3327 O OG1 . THR B 2 114 ? 157.101 166.507 111.446 1.00 33.64  ? 114 THR D OG1 1 
ATOM   3328 C CG2 . THR B 2 114 ? 155.249 165.749 110.117 1.00 24.26  ? 114 THR D CG2 1 
ATOM   3329 N N   . ALA B 2 115 ? 153.768 163.320 112.329 1.00 21.45  ? 115 ALA D N   1 
ATOM   3330 C CA  . ALA B 2 115 ? 152.981 162.123 112.086 1.00 13.74  ? 115 ALA D CA  1 
ATOM   3331 C C   . ALA B 2 115 ? 151.518 162.451 112.319 1.00 11.01  ? 115 ALA D C   1 
ATOM   3332 O O   . ALA B 2 115 ? 151.182 163.489 112.892 1.00 18.15  ? 115 ALA D O   1 
ATOM   3333 C CB  . ALA B 2 115 ? 153.424 160.970 112.991 1.00 11.05  ? 115 ALA D CB  1 
ATOM   3334 N N   . VAL B 2 116 ? 150.652 161.560 111.856 1.00 9.53   ? 116 VAL D N   1 
ATOM   3335 C CA  . VAL B 2 116 ? 149.238 161.609 112.202 1.00 5.55   ? 116 VAL D CA  1 
ATOM   3336 C C   . VAL B 2 116 ? 149.033 160.697 113.401 1.00 13.39  ? 116 VAL D C   1 
ATOM   3337 O O   . VAL B 2 116 ? 149.259 159.488 113.314 1.00 27.32  ? 116 VAL D O   1 
ATOM   3338 C CB  . VAL B 2 116 ? 148.353 161.183 111.023 1.00 0.00   ? 116 VAL D CB  1 
ATOM   3339 C CG1 . VAL B 2 116 ? 146.905 161.194 111.438 1.00 8.36   ? 116 VAL D CG1 1 
ATOM   3340 C CG2 . VAL B 2 116 ? 148.569 162.105 109.846 1.00 15.86  ? 116 VAL D CG2 1 
ATOM   3341 N N   . TYR B 2 117 ? 148.620 161.276 114.522 1.00 7.60   ? 117 TYR D N   1 
ATOM   3342 C CA  . TYR B 2 117 ? 148.494 160.548 115.775 1.00 0.00   ? 117 TYR D CA  1 
ATOM   3343 C C   . TYR B 2 117 ? 147.043 160.140 115.978 1.00 8.37   ? 117 TYR D C   1 
ATOM   3344 O O   . TYR B 2 117 ? 146.166 160.998 116.105 1.00 20.95  ? 117 TYR D O   1 
ATOM   3345 C CB  . TYR B 2 117 ? 148.978 161.397 116.948 1.00 10.14  ? 117 TYR D CB  1 
ATOM   3346 C CG  . TYR B 2 117 ? 150.474 161.581 117.008 1.00 17.13  ? 117 TYR D CG  1 
ATOM   3347 C CD1 . TYR B 2 117 ? 151.119 162.441 116.136 1.00 18.68  ? 117 TYR D CD1 1 
ATOM   3348 C CD2 . TYR B 2 117 ? 151.241 160.906 117.942 1.00 7.63   ? 117 TYR D CD2 1 
ATOM   3349 C CE1 . TYR B 2 117 ? 152.481 162.616 116.184 1.00 10.28  ? 117 TYR D CE1 1 
ATOM   3350 C CE2 . TYR B 2 117 ? 152.606 161.082 117.996 1.00 7.57   ? 117 TYR D CE2 1 
ATOM   3351 C CZ  . TYR B 2 117 ? 153.218 161.937 117.113 1.00 5.12   ? 117 TYR D CZ  1 
ATOM   3352 O OH  . TYR B 2 117 ? 154.576 162.118 117.152 1.00 20.66  ? 117 TYR D OH  1 
ATOM   3353 N N   . TYR B 2 118 ? 146.795 158.837 116.011 1.00 15.98  ? 118 TYR D N   1 
ATOM   3354 C CA  . TYR B 2 118 ? 145.476 158.300 116.302 1.00 2.91   ? 118 TYR D CA  1 
ATOM   3355 C C   . TYR B 2 118 ? 145.444 157.793 117.733 1.00 10.85  ? 118 TYR D C   1 
ATOM   3356 O O   . TYR B 2 118 ? 146.404 157.178 118.204 1.00 18.02  ? 118 TYR D O   1 
ATOM   3357 C CB  . TYR B 2 118 ? 145.110 157.152 115.359 1.00 5.92   ? 118 TYR D CB  1 
ATOM   3358 C CG  . TYR B 2 118 ? 145.348 157.412 113.895 1.00 1.84   ? 118 TYR D CG  1 
ATOM   3359 C CD1 . TYR B 2 118 ? 146.572 157.134 113.311 1.00 0.71   ? 118 TYR D CD1 1 
ATOM   3360 C CD2 . TYR B 2 118 ? 144.339 157.908 113.090 1.00 2.83   ? 118 TYR D CD2 1 
ATOM   3361 C CE1 . TYR B 2 118 ? 146.787 157.363 111.975 1.00 0.00   ? 118 TYR D CE1 1 
ATOM   3362 C CE2 . TYR B 2 118 ? 144.547 158.139 111.753 1.00 1.23   ? 118 TYR D CE2 1 
ATOM   3363 C CZ  . TYR B 2 118 ? 145.770 157.864 111.201 1.00 2.39   ? 118 TYR D CZ  1 
ATOM   3364 O OH  . TYR B 2 118 ? 145.977 158.096 109.864 1.00 15.67  ? 118 TYR D OH  1 
ATOM   3365 N N   . CYS B 2 119 ? 144.343 158.054 118.425 1.00 2.14   ? 119 CYS D N   1 
ATOM   3366 C CA  . CYS B 2 119 ? 144.078 157.409 119.701 1.00 13.02  ? 119 CYS D CA  1 
ATOM   3367 C C   . CYS B 2 119 ? 143.204 156.193 119.430 1.00 26.76  ? 119 CYS D C   1 
ATOM   3368 O O   . CYS B 2 119 ? 142.146 156.308 118.805 1.00 22.53  ? 119 CYS D O   1 
ATOM   3369 C CB  . CYS B 2 119 ? 143.428 158.363 120.705 1.00 9.39   ? 119 CYS D CB  1 
ATOM   3370 S SG  . CYS B 2 119 ? 141.858 159.094 120.240 1.00 37.15  ? 119 CYS D SG  1 
ATOM   3371 N N   . ALA B 2 120 ? 143.671 155.032 119.866 1.00 21.34  ? 120 ALA D N   1 
ATOM   3372 C CA  . ALA B 2 120 ? 143.007 153.767 119.616 1.00 0.00   ? 120 ALA D CA  1 
ATOM   3373 C C   . ALA B 2 120 ? 142.550 153.163 120.935 1.00 7.18   ? 120 ALA D C   1 
ATOM   3374 O O   . ALA B 2 120 ? 143.189 153.343 121.974 1.00 0.00   ? 120 ALA D O   1 
ATOM   3375 C CB  . ALA B 2 120 ? 143.934 152.797 118.878 1.00 8.17   ? 120 ALA D CB  1 
ATOM   3376 N N   . ARG B 2 121 ? 141.435 152.446 120.884 1.00 18.88  ? 121 ARG D N   1 
ATOM   3377 C CA  . ARG B 2 121 ? 140.833 151.833 122.056 1.00 4.74   ? 121 ARG D CA  1 
ATOM   3378 C C   . ARG B 2 121 ? 140.944 150.319 121.966 1.00 4.15   ? 121 ARG D C   1 
ATOM   3379 O O   . ARG B 2 121 ? 140.826 149.742 120.883 1.00 11.63  ? 121 ARG D O   1 
ATOM   3380 C CB  . ARG B 2 121 ? 139.366 152.246 122.191 1.00 0.96   ? 121 ARG D CB  1 
ATOM   3381 C CG  . ARG B 2 121 ? 138.626 151.587 123.331 1.00 5.36   ? 121 ARG D CG  1 
ATOM   3382 C CD  . ARG B 2 121 ? 137.369 150.904 122.831 1.00 12.64  ? 121 ARG D CD  1 
ATOM   3383 N NE  . ARG B 2 121 ? 136.801 149.996 123.819 1.00 10.38  ? 121 ARG D NE  1 
ATOM   3384 C CZ  . ARG B 2 121 ? 136.543 148.715 123.596 1.00 13.15  ? 121 ARG D CZ  1 
ATOM   3385 N NH1 . ARG B 2 121 ? 136.786 148.156 122.424 1.00 9.08   ? 121 ARG D NH1 1 
ATOM   3386 N NH2 . ARG B 2 121 ? 136.021 147.980 124.572 1.00 17.44  ? 121 ARG D NH2 1 
ATOM   3387 N N   . SER B 2 122 ? 141.185 149.683 123.105 1.00 10.47  ? 122 SER D N   1 
ATOM   3388 C CA  . SER B 2 122 ? 141.250 148.235 123.192 1.00 0.80   ? 122 SER D CA  1 
ATOM   3389 C C   . SER B 2 122 ? 140.488 147.781 124.424 1.00 0.00   ? 122 SER D C   1 
ATOM   3390 O O   . SER B 2 122 ? 140.353 148.529 125.392 1.00 15.80  ? 122 SER D O   1 
ATOM   3391 C CB  . SER B 2 122 ? 142.695 147.743 123.258 1.00 7.21   ? 122 SER D CB  1 
ATOM   3392 O OG  . SER B 2 122 ? 142.748 146.339 123.360 1.00 5.93   ? 122 SER D OG  1 
ATOM   3393 N N   . ARG B 2 123 ? 139.980 146.554 124.376 1.00 11.97  ? 123 ARG D N   1 
ATOM   3394 C CA  . ARG B 2 123 ? 139.338 145.976 125.547 1.00 0.00   ? 123 ARG D CA  1 
ATOM   3395 C C   . ARG B 2 123 ? 140.345 145.830 126.676 1.00 3.20   ? 123 ARG D C   1 
ATOM   3396 O O   . ARG B 2 123 ? 141.512 145.505 126.453 1.00 0.00   ? 123 ARG D O   1 
ATOM   3397 C CB  . ARG B 2 123 ? 138.735 144.615 125.210 1.00 0.00   ? 123 ARG D CB  1 
ATOM   3398 C CG  . ARG B 2 123 ? 137.230 144.582 125.237 1.00 0.00   ? 123 ARG D CG  1 
ATOM   3399 C CD  . ARG B 2 123 ? 136.710 143.173 125.020 1.00 6.63   ? 123 ARG D CD  1 
ATOM   3400 N NE  . ARG B 2 123 ? 136.106 142.609 126.221 1.00 19.74  ? 123 ARG D NE  1 
ATOM   3401 C CZ  . ARG B 2 123 ? 134.983 143.042 126.777 1.00 26.54  ? 123 ARG D CZ  1 
ATOM   3402 N NH1 . ARG B 2 123 ? 134.286 144.035 126.249 1.00 21.34  ? 123 ARG D NH1 1 
ATOM   3403 N NH2 . ARG B 2 123 ? 134.541 142.459 127.887 1.00 18.10  ? 123 ARG D NH2 1 
ATOM   3404 N N   . GLN B 2 124 ? 139.902 146.105 127.899 1.00 13.51  ? 124 GLN D N   1 
ATOM   3405 C CA  . GLN B 2 124 ? 140.784 145.866 129.031 1.00 0.00   ? 124 GLN D CA  1 
ATOM   3406 C C   . GLN B 2 124 ? 140.840 144.388 129.376 1.00 8.57   ? 124 GLN D C   1 
ATOM   3407 O O   . GLN B 2 124 ? 141.905 143.864 129.720 1.00 6.75   ? 124 GLN D O   1 
ATOM   3408 C CB  . GLN B 2 124 ? 140.331 146.672 130.242 1.00 0.00   ? 124 GLN D CB  1 
ATOM   3409 C CG  . GLN B 2 124 ? 141.179 146.432 131.462 1.00 0.00   ? 124 GLN D CG  1 
ATOM   3410 C CD  . GLN B 2 124 ? 142.626 146.776 131.224 1.00 1.40   ? 124 GLN D CD  1 
ATOM   3411 O OE1 . GLN B 2 124 ? 142.969 147.934 131.011 1.00 11.34  ? 124 GLN D OE1 1 
ATOM   3412 N NE2 . GLN B 2 124 ? 143.486 145.770 131.248 1.00 10.13  ? 124 GLN D NE2 1 
ATOM   3413 N N   . PHE B 2 125 ? 139.714 143.699 129.275 1.00 4.88   ? 125 PHE D N   1 
ATOM   3414 C CA  . PHE B 2 125 ? 139.611 142.327 129.738 1.00 0.00   ? 125 PHE D CA  1 
ATOM   3415 C C   . PHE B 2 125 ? 139.490 141.399 128.542 1.00 10.37  ? 125 PHE D C   1 
ATOM   3416 O O   . PHE B 2 125 ? 138.453 141.353 127.873 1.00 0.19   ? 125 PHE D O   1 
ATOM   3417 C CB  . PHE B 2 125 ? 138.459 142.181 130.724 1.00 1.79   ? 125 PHE D CB  1 
ATOM   3418 C CG  . PHE B 2 125 ? 138.702 142.929 131.990 1.00 13.58  ? 125 PHE D CG  1 
ATOM   3419 C CD1 . PHE B 2 125 ? 139.750 142.570 132.813 1.00 0.06   ? 125 PHE D CD1 1 
ATOM   3420 C CD2 . PHE B 2 125 ? 137.948 144.034 132.321 1.00 9.77   ? 125 PHE D CD2 1 
ATOM   3421 C CE1 . PHE B 2 125 ? 140.015 143.270 133.955 1.00 0.00   ? 125 PHE D CE1 1 
ATOM   3422 C CE2 . PHE B 2 125 ? 138.213 144.735 133.467 1.00 0.00   ? 125 PHE D CE2 1 
ATOM   3423 C CZ  . PHE B 2 125 ? 139.245 144.348 134.284 1.00 6.60   ? 125 PHE D CZ  1 
ATOM   3424 N N   . TRP B 2 126 ? 140.588 140.694 128.279 1.00 17.63  ? 126 TRP D N   1 
ATOM   3425 C CA  . TRP B 2 126 ? 140.666 139.560 127.370 1.00 15.90  ? 126 TRP D CA  1 
ATOM   3426 C C   . TRP B 2 126 ? 140.549 140.003 125.919 1.00 34.26  ? 126 TRP D C   1 
ATOM   3427 O O   . TRP B 2 126 ? 139.833 139.393 125.123 1.00 39.44  ? 126 TRP D O   1 
ATOM   3428 C CB  . TRP B 2 126 ? 139.634 138.479 127.708 1.00 22.66  ? 126 TRP D CB  1 
ATOM   3429 C CG  . TRP B 2 126 ? 139.399 138.216 129.185 1.00 10.56  ? 126 TRP D CG  1 
ATOM   3430 C CD1 . TRP B 2 126 ? 138.270 137.689 129.731 1.00 4.69   ? 126 TRP D CD1 1 
ATOM   3431 C CD2 . TRP B 2 126 ? 140.293 138.470 130.288 1.00 2.46   ? 126 TRP D CD2 1 
ATOM   3432 N NE1 . TRP B 2 126 ? 138.399 137.589 131.087 1.00 4.68   ? 126 TRP D NE1 1 
ATOM   3433 C CE2 . TRP B 2 126 ? 139.627 138.065 131.456 1.00 11.90  ? 126 TRP D CE2 1 
ATOM   3434 C CE3 . TRP B 2 126 ? 141.586 138.995 130.401 1.00 0.00   ? 126 TRP D CE3 1 
ATOM   3435 C CZ2 . TRP B 2 126 ? 140.203 138.170 132.713 1.00 24.42  ? 126 TRP D CZ2 1 
ATOM   3436 C CZ3 . TRP B 2 126 ? 142.149 139.106 131.641 1.00 24.73  ? 126 TRP D CZ3 1 
ATOM   3437 C CH2 . TRP B 2 126 ? 141.463 138.692 132.785 1.00 33.93  ? 126 TRP D CH2 1 
ATOM   3438 N N   . TYR B 2 127 ? 141.255 141.080 125.586 1.00 11.93  ? 127 TYR D N   1 
ATOM   3439 C CA  . TYR B 2 127 ? 141.566 141.427 124.208 1.00 28.27  ? 127 TYR D CA  1 
ATOM   3440 C C   . TYR B 2 127 ? 142.548 142.584 124.227 1.00 10.73  ? 127 TYR D C   1 
ATOM   3441 O O   . TYR B 2 127 ? 142.399 143.499 125.033 1.00 21.74  ? 127 TYR D O   1 
ATOM   3442 C CB  . TYR B 2 127 ? 140.300 141.795 123.423 1.00 23.65  ? 127 TYR D CB  1 
ATOM   3443 C CG  . TYR B 2 127 ? 140.534 142.047 121.958 1.00 16.56  ? 127 TYR D CG  1 
ATOM   3444 C CD1 . TYR B 2 127 ? 141.601 141.465 121.298 1.00 1.23   ? 127 TYR D CD1 1 
ATOM   3445 C CD2 . TYR B 2 127 ? 139.683 142.866 121.235 1.00 25.66  ? 127 TYR D CD2 1 
ATOM   3446 C CE1 . TYR B 2 127 ? 141.822 141.700 119.971 1.00 16.89  ? 127 TYR D CE1 1 
ATOM   3447 C CE2 . TYR B 2 127 ? 139.894 143.101 119.900 1.00 24.61  ? 127 TYR D CE2 1 
ATOM   3448 C CZ  . TYR B 2 127 ? 140.966 142.515 119.276 1.00 18.84  ? 127 TYR D CZ  1 
ATOM   3449 O OH  . TYR B 2 127 ? 141.187 142.747 117.945 1.00 33.82  ? 127 TYR D OH  1 
ATOM   3450 N N   . SER B 2 128 ? 143.569 142.525 123.369 1.00 2.40   ? 128 SER D N   1 
ATOM   3451 C CA  . SER B 2 128 ? 144.413 143.690 123.096 1.00 19.19  ? 128 SER D CA  1 
ATOM   3452 C C   . SER B 2 128 ? 144.554 143.839 121.581 1.00 27.11  ? 128 SER D C   1 
ATOM   3453 O O   . SER B 2 128 ? 145.579 143.495 120.997 1.00 27.55  ? 128 SER D O   1 
ATOM   3454 C CB  . SER B 2 128 ? 145.756 143.570 123.778 1.00 19.42  ? 128 SER D CB  1 
ATOM   3455 O OG  . SER B 2 128 ? 146.526 144.736 123.551 1.00 19.89  ? 128 SER D OG  1 
ATOM   3456 N N   . GLY B 2 129 ? 143.530 144.415 120.957 1.00 36.96  ? 129 GLY D N   1 
ATOM   3457 C CA  . GLY B 2 129 ? 143.514 144.680 119.533 1.00 5.83   ? 129 GLY D CA  1 
ATOM   3458 C C   . GLY B 2 129 ? 142.659 145.897 119.259 1.00 16.17  ? 129 GLY D C   1 
ATOM   3459 O O   . GLY B 2 129 ? 141.503 145.957 119.682 1.00 23.24  ? 129 GLY D O   1 
ATOM   3460 N N   . LEU B 2 130 ? 143.216 146.870 118.548 1.00 6.91   ? 130 LEU D N   1 
ATOM   3461 C CA  . LEU B 2 130 ? 142.624 148.197 118.464 1.00 0.70   ? 130 LEU D CA  1 
ATOM   3462 C C   . LEU B 2 130 ? 141.417 148.217 117.536 1.00 0.00   ? 130 LEU D C   1 
ATOM   3463 O O   . LEU B 2 130 ? 141.555 148.433 116.330 1.00 11.99  ? 130 LEU D O   1 
ATOM   3464 C CB  . LEU B 2 130 ? 143.685 149.196 118.009 1.00 15.50  ? 130 LEU D CB  1 
ATOM   3465 C CG  . LEU B 2 130 ? 145.078 148.883 118.560 1.00 3.02   ? 130 LEU D CG  1 
ATOM   3466 C CD1 . LEU B 2 130 ? 146.151 149.682 117.858 1.00 8.19   ? 130 LEU D CD1 1 
ATOM   3467 C CD2 . LEU B 2 130 ? 145.126 149.131 120.047 1.00 0.00   ? 130 LEU D CD2 1 
ATOM   3468 N N   . ASP B 2 131 ? 140.229 147.998 118.093 1.00 0.00   ? 131 ASP D N   1 
ATOM   3469 C CA  . ASP B 2 131 ? 139.013 147.914 117.297 1.00 14.78  ? 131 ASP D CA  1 
ATOM   3470 C C   . ASP B 2 131 ? 138.376 149.265 117.021 1.00 14.58  ? 131 ASP D C   1 
ATOM   3471 O O   . ASP B 2 131 ? 137.533 149.361 116.123 1.00 19.64  ? 131 ASP D O   1 
ATOM   3472 C CB  . ASP B 2 131 ? 137.988 147.011 117.990 1.00 20.09  ? 131 ASP D CB  1 
ATOM   3473 C CG  . ASP B 2 131 ? 137.854 147.310 119.466 1.00 21.54  ? 131 ASP D CG  1 
ATOM   3474 O OD1 . ASP B 2 131 ? 138.769 147.938 120.033 1.00 9.35   ? 131 ASP D OD1 1 
ATOM   3475 O OD2 . ASP B 2 131 ? 136.834 146.910 120.063 1.00 21.44  ? 131 ASP D OD2 1 
ATOM   3476 N N   . TYR B 2 132 ? 138.746 150.303 117.764 1.00 10.03  ? 132 TYR D N   1 
ATOM   3477 C CA  . TYR B 2 132 ? 138.212 151.640 117.556 1.00 11.45  ? 132 TYR D CA  1 
ATOM   3478 C C   . TYR B 2 132 ? 139.366 152.620 117.430 1.00 10.11  ? 132 TYR D C   1 
ATOM   3479 O O   . TYR B 2 132 ? 140.300 152.589 118.235 1.00 2.05   ? 132 TYR D O   1 
ATOM   3480 C CB  . TYR B 2 132 ? 137.282 152.050 118.698 1.00 11.84  ? 132 TYR D CB  1 
ATOM   3481 C CG  . TYR B 2 132 ? 135.960 151.326 118.678 1.00 18.81  ? 132 TYR D CG  1 
ATOM   3482 C CD1 . TYR B 2 132 ? 134.930 151.747 117.852 1.00 21.91  ? 132 TYR D CD1 1 
ATOM   3483 C CD2 . TYR B 2 132 ? 135.744 150.215 119.479 1.00 18.58  ? 132 TYR D CD2 1 
ATOM   3484 C CE1 . TYR B 2 132 ? 133.721 151.084 117.828 1.00 21.09  ? 132 TYR D CE1 1 
ATOM   3485 C CE2 . TYR B 2 132 ? 134.540 149.546 119.459 1.00 16.35  ? 132 TYR D CE2 1 
ATOM   3486 C CZ  . TYR B 2 132 ? 133.532 149.985 118.633 1.00 20.99  ? 132 TYR D CZ  1 
ATOM   3487 O OH  . TYR B 2 132 ? 132.328 149.323 118.612 1.00 26.25  ? 132 TYR D OH  1 
ATOM   3488 N N   . TRP B 2 133 ? 139.297 153.480 116.418 1.00 0.00   ? 133 TRP D N   1 
ATOM   3489 C CA  . TRP B 2 133 ? 140.323 154.472 116.151 1.00 3.07   ? 133 TRP D CA  1 
ATOM   3490 C C   . TRP B 2 133 ? 139.678 155.842 116.013 1.00 18.78  ? 133 TRP D C   1 
ATOM   3491 O O   . TRP B 2 133 ? 138.487 155.964 115.721 1.00 17.54  ? 133 TRP D O   1 
ATOM   3492 C CB  . TRP B 2 133 ? 141.108 154.159 114.869 1.00 7.64   ? 133 TRP D CB  1 
ATOM   3493 C CG  . TRP B 2 133 ? 141.892 152.887 114.893 1.00 4.60   ? 133 TRP D CG  1 
ATOM   3494 C CD1 . TRP B 2 133 ? 141.398 151.620 114.963 1.00 9.91   ? 133 TRP D CD1 1 
ATOM   3495 C CD2 . TRP B 2 133 ? 143.315 152.759 114.826 1.00 0.00   ? 133 TRP D CD2 1 
ATOM   3496 N NE1 . TRP B 2 133 ? 142.422 150.711 114.953 1.00 0.00   ? 133 TRP D NE1 1 
ATOM   3497 C CE2 . TRP B 2 133 ? 143.611 151.384 114.869 1.00 0.00   ? 133 TRP D CE2 1 
ATOM   3498 C CE3 . TRP B 2 133 ? 144.367 153.673 114.736 1.00 0.00   ? 133 TRP D CE3 1 
ATOM   3499 C CZ2 . TRP B 2 133 ? 144.912 150.902 114.824 1.00 0.00   ? 133 TRP D CZ2 1 
ATOM   3500 C CZ3 . TRP B 2 133 ? 145.658 153.191 114.691 1.00 0.00   ? 133 TRP D CZ3 1 
ATOM   3501 C CH2 . TRP B 2 133 ? 145.920 151.818 114.736 1.00 10.82  ? 133 TRP D CH2 1 
ATOM   3502 N N   . GLY B 2 134 ? 140.484 156.879 116.233 1.00 17.54  ? 134 GLY D N   1 
ATOM   3503 C CA  . GLY B 2 134 ? 140.084 158.231 115.916 1.00 1.46   ? 134 GLY D CA  1 
ATOM   3504 C C   . GLY B 2 134 ? 140.520 158.625 114.518 1.00 8.78   ? 134 GLY D C   1 
ATOM   3505 O O   . GLY B 2 134 ? 141.215 157.892 113.820 1.00 31.42  ? 134 GLY D O   1 
ATOM   3506 N N   . GLN B 2 135 ? 140.097 159.820 114.106 1.00 10.70  ? 135 GLN D N   1 
ATOM   3507 C CA  . GLN B 2 135 ? 140.438 160.296 112.771 1.00 1.30   ? 135 GLN D CA  1 
ATOM   3508 C C   . GLN B 2 135 ? 141.908 160.664 112.640 1.00 12.33  ? 135 GLN D C   1 
ATOM   3509 O O   . GLN B 2 135 ? 142.430 160.677 111.522 1.00 17.36  ? 135 GLN D O   1 
ATOM   3510 C CB  . GLN B 2 135 ? 139.566 161.494 112.399 1.00 18.03  ? 135 GLN D CB  1 
ATOM   3511 C CG  . GLN B 2 135 ? 140.041 162.813 112.974 1.00 19.28  ? 135 GLN D CG  1 
ATOM   3512 C CD  . GLN B 2 135 ? 139.384 163.136 114.299 1.00 27.31  ? 135 GLN D CD  1 
ATOM   3513 O OE1 . GLN B 2 135 ? 138.245 162.745 114.553 1.00 34.52  ? 135 GLN D OE1 1 
ATOM   3514 N NE2 . GLN B 2 135 ? 140.103 163.849 115.156 1.00 27.07  ? 135 GLN D NE2 1 
ATOM   3515 N N   . GLY B 2 136 ? 142.584 160.961 113.746 1.00 21.36  ? 136 GLY D N   1 
ATOM   3516 C CA  . GLY B 2 136 ? 143.983 161.330 113.706 1.00 7.64   ? 136 GLY D CA  1 
ATOM   3517 C C   . GLY B 2 136 ? 144.209 162.824 113.629 1.00 15.15  ? 136 GLY D C   1 
ATOM   3518 O O   . GLY B 2 136 ? 143.467 163.535 112.947 1.00 25.05  ? 136 GLY D O   1 
ATOM   3519 N N   . THR B 2 137 ? 145.228 163.312 114.329 1.00 21.04  ? 137 THR D N   1 
ATOM   3520 C CA  . THR B 2 137 ? 145.632 164.709 114.271 1.00 14.97  ? 137 THR D CA  1 
ATOM   3521 C C   . THR B 2 137 ? 147.019 164.801 113.658 1.00 9.27   ? 137 THR D C   1 
ATOM   3522 O O   . THR B 2 137 ? 147.956 164.158 114.139 1.00 17.00  ? 137 THR D O   1 
ATOM   3523 C CB  . THR B 2 137 ? 145.635 165.352 115.661 1.00 11.30  ? 137 THR D CB  1 
ATOM   3524 O OG1 . THR B 2 137 ? 146.102 164.408 116.630 1.00 17.16  ? 137 THR D OG1 1 
ATOM   3525 C CG2 . THR B 2 137 ? 144.242 165.816 116.040 1.00 15.47  ? 137 THR D CG2 1 
ATOM   3526 N N   . LEU B 2 138 ? 147.148 165.599 112.604 1.00 17.62  ? 138 LEU D N   1 
ATOM   3527 C CA  . LEU B 2 138 ? 148.442 165.824 111.972 1.00 18.73  ? 138 LEU D CA  1 
ATOM   3528 C C   . LEU B 2 138 ? 149.246 166.773 112.849 1.00 24.86  ? 138 LEU D C   1 
ATOM   3529 O O   . LEU B 2 138 ? 148.860 167.930 113.041 1.00 23.41  ? 138 LEU D O   1 
ATOM   3530 C CB  . LEU B 2 138 ? 148.263 166.384 110.565 1.00 5.46   ? 138 LEU D CB  1 
ATOM   3531 C CG  . LEU B 2 138 ? 149.519 166.891 109.855 1.00 16.93  ? 138 LEU D CG  1 
ATOM   3532 C CD1 . LEU B 2 138 ? 150.625 165.851 109.863 1.00 16.93  ? 138 LEU D CD1 1 
ATOM   3533 C CD2 . LEU B 2 138 ? 149.188 167.300 108.434 1.00 24.85  ? 138 LEU D CD2 1 
ATOM   3534 N N   . VAL B 2 139 ? 150.357 166.285 113.387 1.00 13.78  ? 139 VAL D N   1 
ATOM   3535 C CA  . VAL B 2 139 ? 151.238 167.064 114.246 1.00 13.68  ? 139 VAL D CA  1 
ATOM   3536 C C   . VAL B 2 139 ? 152.507 167.350 113.456 1.00 16.89  ? 139 VAL D C   1 
ATOM   3537 O O   . VAL B 2 139 ? 153.318 166.447 113.219 1.00 21.01  ? 139 VAL D O   1 
ATOM   3538 C CB  . VAL B 2 139 ? 151.545 166.327 115.556 1.00 12.53  ? 139 VAL D CB  1 
ATOM   3539 C CG1 . VAL B 2 139 ? 152.723 166.964 116.274 1.00 14.37  ? 139 VAL D CG1 1 
ATOM   3540 C CG2 . VAL B 2 139 ? 150.315 166.303 116.445 1.00 12.32  ? 139 VAL D CG2 1 
ATOM   3541 N N   . THR B 2 140 ? 152.684 168.600 113.045 1.00 18.95  ? 140 THR D N   1 
ATOM   3542 C CA  . THR B 2 140 ? 153.838 169.008 112.255 1.00 19.90  ? 140 THR D CA  1 
ATOM   3543 C C   . THR B 2 140 ? 154.837 169.699 113.170 1.00 26.72  ? 140 THR D C   1 
ATOM   3544 O O   . THR B 2 140 ? 154.492 170.676 113.843 1.00 34.49  ? 140 THR D O   1 
ATOM   3545 C CB  . THR B 2 140 ? 153.429 169.940 111.116 1.00 24.81  ? 140 THR D CB  1 
ATOM   3546 O OG1 . THR B 2 140 ? 152.161 169.532 110.589 1.00 34.34  ? 140 THR D OG1 1 
ATOM   3547 C CG2 . THR B 2 140 ? 154.466 169.901 110.008 1.00 24.67  ? 140 THR D CG2 1 
ATOM   3548 N N   . VAL B 2 141 ? 156.067 169.196 113.190 1.00 24.99  ? 141 VAL D N   1 
ATOM   3549 C CA  . VAL B 2 141 ? 157.120 169.699 114.065 1.00 21.80  ? 141 VAL D CA  1 
ATOM   3550 C C   . VAL B 2 141 ? 158.265 170.156 113.173 1.00 29.46  ? 141 VAL D C   1 
ATOM   3551 O O   . VAL B 2 141 ? 159.128 169.355 112.797 1.00 37.03  ? 141 VAL D O   1 
ATOM   3552 C CB  . VAL B 2 141 ? 157.591 168.646 115.071 1.00 16.45  ? 141 VAL D CB  1 
ATOM   3553 C CG1 . VAL B 2 141 ? 158.529 169.269 116.080 1.00 31.33  ? 141 VAL D CG1 1 
ATOM   3554 C CG2 . VAL B 2 141 ? 156.411 168.007 115.770 1.00 16.99  ? 141 VAL D CG2 1 
ATOM   3555 N N   . SER B 2 142 ? 158.291 171.445 112.840 1.00 40.53  ? 142 SER D N   1 
ATOM   3556 C CA  . SER B 2 142 ? 159.390 171.999 112.063 1.00 44.26  ? 142 SER D CA  1 
ATOM   3557 C C   . SER B 2 142 ? 159.527 173.481 112.369 1.00 47.20  ? 142 SER D C   1 
ATOM   3558 O O   . SER B 2 142 ? 158.580 174.135 112.812 1.00 51.37  ? 142 SER D O   1 
ATOM   3559 C CB  . SER B 2 142 ? 159.184 171.787 110.563 1.00 47.77  ? 142 SER D CB  1 
ATOM   3560 O OG  . SER B 2 142 ? 158.237 172.706 110.066 1.00 49.18  ? 142 SER D OG  1 
ATOM   3561 N N   . SER B 2 143 ? 160.724 174.008 112.111 1.00 52.35  ? 143 SER D N   1 
ATOM   3562 C CA  . SER B 2 143 ? 161.043 175.390 112.444 1.00 56.15  ? 143 SER D CA  1 
ATOM   3563 C C   . SER B 2 143 ? 160.588 176.389 111.389 1.00 54.09  ? 143 SER D C   1 
ATOM   3564 O O   . SER B 2 143 ? 160.601 177.593 111.662 1.00 58.07  ? 143 SER D O   1 
ATOM   3565 C CB  . SER B 2 143 ? 162.550 175.543 112.663 1.00 57.11  ? 143 SER D CB  1 
ATOM   3566 O OG  . SER B 2 143 ? 163.283 174.833 111.679 1.00 58.09  ? 143 SER D OG  1 
ATOM   3567 N N   . ALA B 2 144 ? 160.192 175.931 110.206 1.00 55.83  ? 144 ALA D N   1 
ATOM   3568 C CA  . ALA B 2 144 ? 159.781 176.848 109.153 1.00 58.08  ? 144 ALA D CA  1 
ATOM   3569 C C   . ALA B 2 144 ? 158.489 177.565 109.529 1.00 60.84  ? 144 ALA D C   1 
ATOM   3570 O O   . ALA B 2 144 ? 157.629 177.024 110.228 1.00 58.33  ? 144 ALA D O   1 
ATOM   3571 C CB  . ALA B 2 144 ? 159.599 176.102 107.833 1.00 59.63  ? 144 ALA D CB  1 
ATOM   3572 N N   . SER B 2 145 ? 158.363 178.800 109.061 1.00 70.79  ? 145 SER D N   1 
ATOM   3573 C CA  . SER B 2 145 ? 157.182 179.611 109.305 1.00 68.33  ? 145 SER D CA  1 
ATOM   3574 C C   . SER B 2 145 ? 156.299 179.648 108.065 1.00 69.21  ? 145 SER D C   1 
ATOM   3575 O O   . SER B 2 145 ? 156.749 179.406 106.943 1.00 70.06  ? 145 SER D O   1 
ATOM   3576 C CB  . SER B 2 145 ? 157.571 181.035 109.708 1.00 67.50  ? 145 SER D CB  1 
ATOM   3577 O OG  . SER B 2 145 ? 158.051 181.762 108.591 1.00 66.49  ? 145 SER D OG  1 
ATOM   3578 N N   . THR B 2 146 ? 155.025 179.961 108.288 1.00 77.01  ? 146 THR D N   1 
ATOM   3579 C CA  . THR B 2 146 ? 154.064 180.042 107.197 1.00 77.85  ? 146 THR D CA  1 
ATOM   3580 C C   . THR B 2 146 ? 154.495 181.099 106.187 1.00 76.15  ? 146 THR D C   1 
ATOM   3581 O O   . THR B 2 146 ? 154.894 182.205 106.561 1.00 78.93  ? 146 THR D O   1 
ATOM   3582 C CB  . THR B 2 146 ? 152.679 180.373 107.753 1.00 80.04  ? 146 THR D CB  1 
ATOM   3583 O OG1 . THR B 2 146 ? 152.254 179.328 108.636 1.00 76.90  ? 146 THR D OG1 1 
ATOM   3584 C CG2 . THR B 2 146 ? 151.672 180.516 106.628 1.00 78.19  ? 146 THR D CG2 1 
ATOM   3585 N N   . LYS B 2 147 ? 154.424 180.754 104.904 1.00 77.84  ? 147 LYS D N   1 
ATOM   3586 C CA  . LYS B 2 147 ? 154.820 181.678 103.852 1.00 81.34  ? 147 LYS D CA  1 
ATOM   3587 C C   . LYS B 2 147 ? 153.961 181.433 102.620 1.00 79.72  ? 147 LYS D C   1 
ATOM   3588 O O   . LYS B 2 147 ? 153.305 180.397 102.488 1.00 79.50  ? 147 LYS D O   1 
ATOM   3589 C CB  . LYS B 2 147 ? 156.311 181.546 103.518 1.00 80.48  ? 147 LYS D CB  1 
ATOM   3590 C CG  . LYS B 2 147 ? 156.656 180.361 102.640 1.00 80.88  ? 147 LYS D CG  1 
ATOM   3591 C CD  . LYS B 2 147 ? 158.096 180.444 102.167 1.00 79.27  ? 147 LYS D CD  1 
ATOM   3592 C CE  . LYS B 2 147 ? 158.379 181.788 101.519 1.00 77.58  ? 147 LYS D CE  1 
ATOM   3593 N NZ  . LYS B 2 147 ? 159.821 181.959 101.203 1.00 79.57  ? 147 LYS D NZ  1 
ATOM   3594 N N   . GLY B 2 148 ? 153.969 182.411 101.716 1.00 84.09  ? 148 GLY D N   1 
ATOM   3595 C CA  . GLY B 2 148 ? 153.142 182.367 100.533 1.00 85.09  ? 148 GLY D CA  1 
ATOM   3596 C C   . GLY B 2 148 ? 153.863 181.820 99.319  1.00 84.82  ? 148 GLY D C   1 
ATOM   3597 O O   . GLY B 2 148 ? 155.024 182.145 99.052  1.00 87.27  ? 148 GLY D O   1 
ATOM   3598 N N   . PRO B 2 149 ? 153.178 180.974 98.559  1.00 85.79  ? 149 PRO D N   1 
ATOM   3599 C CA  . PRO B 2 149 ? 153.777 180.362 97.372  1.00 85.82  ? 149 PRO D CA  1 
ATOM   3600 C C   . PRO B 2 149 ? 153.827 181.304 96.177  1.00 87.42  ? 149 PRO D C   1 
ATOM   3601 O O   . PRO B 2 149 ? 153.173 182.348 96.136  1.00 88.72  ? 149 PRO D O   1 
ATOM   3602 C CB  . PRO B 2 149 ? 152.810 179.198 97.097  1.00 84.87  ? 149 PRO D CB  1 
ATOM   3603 C CG  . PRO B 2 149 ? 151.518 179.764 97.605  1.00 85.69  ? 149 PRO D CG  1 
ATOM   3604 C CD  . PRO B 2 149 ? 151.980 180.217 98.940  1.00 86.77  ? 149 PRO D CD  1 
ATOM   3605 N N   . SER B 2 150 ? 154.625 180.901 95.192  1.00 96.34  ? 150 SER D N   1 
ATOM   3606 C CA  . SER B 2 150 ? 154.746 181.600 93.921  1.00 96.64  ? 150 SER D CA  1 
ATOM   3607 C C   . SER B 2 150 ? 154.433 180.629 92.792  1.00 95.95  ? 150 SER D C   1 
ATOM   3608 O O   . SER B 2 150 ? 154.987 179.526 92.748  1.00 96.44  ? 150 SER D O   1 
ATOM   3609 C CB  . SER B 2 150 ? 156.149 182.189 93.753  1.00 95.33  ? 150 SER D CB  1 
ATOM   3610 O OG  . SER B 2 150 ? 157.127 181.343 94.333  1.00 94.29  ? 150 SER D OG  1 
ATOM   3611 N N   . VAL B 2 151 ? 153.551 181.037 91.886  1.00 105.83 ? 151 VAL D N   1 
ATOM   3612 C CA  . VAL B 2 151 ? 153.081 180.170 90.811  1.00 107.04 ? 151 VAL D CA  1 
ATOM   3613 C C   . VAL B 2 151 ? 153.938 180.405 89.576  1.00 107.50 ? 151 VAL D C   1 
ATOM   3614 O O   . VAL B 2 151 ? 153.995 181.522 89.051  1.00 109.16 ? 151 VAL D O   1 
ATOM   3615 C CB  . VAL B 2 151 ? 151.598 180.419 90.508  1.00 106.60 ? 151 VAL D CB  1 
ATOM   3616 C CG1 . VAL B 2 151 ? 151.188 179.683 89.245  1.00 105.44 ? 151 VAL D CG1 1 
ATOM   3617 C CG2 . VAL B 2 151 ? 150.752 179.984 91.684  1.00 105.55 ? 151 VAL D CG2 1 
ATOM   3618 N N   . PHE B 2 152 ? 154.594 179.352 89.107  1.00 107.64 ? 152 PHE D N   1 
ATOM   3619 C CA  . PHE B 2 152 ? 155.512 179.431 87.971  1.00 108.59 ? 152 PHE D CA  1 
ATOM   3620 C C   . PHE B 2 152 ? 154.988 178.561 86.839  1.00 109.21 ? 152 PHE D C   1 
ATOM   3621 O O   . PHE B 2 152 ? 155.062 177.321 86.933  1.00 108.81 ? 152 PHE D O   1 
ATOM   3622 C CB  . PHE B 2 152 ? 156.911 178.987 88.395  1.00 108.54 ? 152 PHE D CB  1 
ATOM   3623 C CG  . PHE B 2 152 ? 157.657 180.017 89.196  1.00 109.86 ? 152 PHE D CG  1 
ATOM   3624 C CD1 . PHE B 2 152 ? 157.094 181.255 89.459  1.00 110.00 ? 152 PHE D CD1 1 
ATOM   3625 C CD2 . PHE B 2 152 ? 158.906 179.735 89.716  1.00 110.10 ? 152 PHE D CD2 1 
ATOM   3626 C CE1 . PHE B 2 152 ? 157.772 182.198 90.202  1.00 110.06 ? 152 PHE D CE1 1 
ATOM   3627 C CE2 . PHE B 2 152 ? 159.590 180.674 90.461  1.00 110.57 ? 152 PHE D CE2 1 
ATOM   3628 C CZ  . PHE B 2 152 ? 159.021 181.907 90.705  1.00 110.57 ? 152 PHE D CZ  1 
ATOM   3629 N N   . PRO B 2 153 ? 154.453 179.141 85.767  1.00 114.98 ? 153 PRO D N   1 
ATOM   3630 C CA  . PRO B 2 153 ? 153.809 178.326 84.731  1.00 114.76 ? 153 PRO D CA  1 
ATOM   3631 C C   . PRO B 2 153 ? 154.801 177.450 83.982  1.00 114.27 ? 153 PRO D C   1 
ATOM   3632 O O   . PRO B 2 153 ? 155.973 177.794 83.817  1.00 114.43 ? 153 PRO D O   1 
ATOM   3633 C CB  . PRO B 2 153 ? 153.182 179.370 83.800  1.00 114.36 ? 153 PRO D CB  1 
ATOM   3634 C CG  . PRO B 2 153 ? 154.031 180.583 83.981  1.00 114.82 ? 153 PRO D CG  1 
ATOM   3635 C CD  . PRO B 2 153 ? 154.477 180.572 85.417  1.00 114.45 ? 153 PRO D CD  1 
ATOM   3636 N N   . LEU B 2 154 ? 154.309 176.301 83.523  1.00 113.53 ? 154 LEU D N   1 
ATOM   3637 C CA  . LEU B 2 154 ? 155.083 175.387 82.690  1.00 114.22 ? 154 LEU D CA  1 
ATOM   3638 C C   . LEU B 2 154 ? 154.664 175.603 81.241  1.00 114.24 ? 154 LEU D C   1 
ATOM   3639 O O   . LEU B 2 154 ? 153.563 175.210 80.841  1.00 113.62 ? 154 LEU D O   1 
ATOM   3640 C CB  . LEU B 2 154 ? 154.869 173.937 83.117  1.00 114.47 ? 154 LEU D CB  1 
ATOM   3641 C CG  . LEU B 2 154 ? 155.125 173.607 84.589  1.00 113.27 ? 154 LEU D CG  1 
ATOM   3642 C CD1 . LEU B 2 154 ? 154.325 172.387 85.016  1.00 112.07 ? 154 LEU D CD1 1 
ATOM   3643 C CD2 . LEU B 2 154 ? 156.610 173.398 84.846  1.00 113.35 ? 154 LEU D CD2 1 
ATOM   3644 N N   . ALA B 2 155 ? 155.541 176.225 80.460  1.00 122.24 ? 155 ALA D N   1 
ATOM   3645 C CA  . ALA B 2 155 ? 155.212 176.552 79.082  1.00 122.46 ? 155 ALA D CA  1 
ATOM   3646 C C   . ALA B 2 155 ? 155.045 175.277 78.259  1.00 122.64 ? 155 ALA D C   1 
ATOM   3647 O O   . ALA B 2 155 ? 155.820 174.329 78.414  1.00 123.42 ? 155 ALA D O   1 
ATOM   3648 C CB  . ALA B 2 155 ? 156.298 177.432 78.465  1.00 121.05 ? 155 ALA D CB  1 
ATOM   3649 N N   . PRO B 2 156 ? 154.046 175.222 77.381  1.00 126.92 ? 156 PRO D N   1 
ATOM   3650 C CA  . PRO B 2 156 ? 153.835 174.031 76.547  1.00 126.95 ? 156 PRO D CA  1 
ATOM   3651 C C   . PRO B 2 156 ? 154.816 174.001 75.385  1.00 127.87 ? 156 PRO D C   1 
ATOM   3652 O O   . PRO B 2 156 ? 154.719 174.798 74.448  1.00 127.93 ? 156 PRO D O   1 
ATOM   3653 C CB  . PRO B 2 156 ? 152.383 174.193 76.068  1.00 127.01 ? 156 PRO D CB  1 
ATOM   3654 C CG  . PRO B 2 156 ? 151.846 175.436 76.746  1.00 127.56 ? 156 PRO D CG  1 
ATOM   3655 C CD  . PRO B 2 156 ? 153.024 176.249 77.141  1.00 127.41 ? 156 PRO D CD  1 
ATOM   3656 N N   . SER B 2 157 ? 155.768 173.073 75.445  1.00 134.42 ? 157 SER D N   1 
ATOM   3657 C CA  . SER B 2 157 ? 156.745 172.899 74.372  1.00 134.57 ? 157 SER D CA  1 
ATOM   3658 C C   . SER B 2 157 ? 156.047 172.197 73.214  1.00 134.66 ? 157 SER D C   1 
ATOM   3659 O O   . SER B 2 157 ? 156.013 170.969 73.128  1.00 133.95 ? 157 SER D O   1 
ATOM   3660 C CB  . SER B 2 157 ? 157.953 172.113 74.862  1.00 133.76 ? 157 SER D CB  1 
ATOM   3661 O OG  . SER B 2 157 ? 158.986 172.115 73.893  1.00 134.51 ? 157 SER D OG  1 
ATOM   3662 N N   . SER B 2 158 ? 155.482 172.998 72.306  1.00 138.84 ? 158 SER D N   1 
ATOM   3663 C CA  . SER B 2 158 ? 154.701 172.456 71.200  1.00 138.81 ? 158 SER D CA  1 
ATOM   3664 C C   . SER B 2 158 ? 155.538 171.625 70.236  1.00 139.53 ? 158 SER D C   1 
ATOM   3665 O O   . SER B 2 158 ? 154.973 170.852 69.455  1.00 139.61 ? 158 SER D O   1 
ATOM   3666 C CB  . SER B 2 158 ? 154.015 173.591 70.438  1.00 138.26 ? 158 SER D CB  1 
ATOM   3667 O OG  . SER B 2 158 ? 153.354 173.103 69.284  1.00 138.92 ? 158 SER D OG  1 
ATOM   3668 N N   . LYS B 2 159 ? 156.862 171.763 70.270  1.00 142.15 ? 159 LYS D N   1 
ATOM   3669 C CA  . LYS B 2 159 ? 157.745 171.029 69.372  1.00 142.40 ? 159 LYS D CA  1 
ATOM   3670 C C   . LYS B 2 159 ? 158.318 169.766 70.000  1.00 142.14 ? 159 LYS D C   1 
ATOM   3671 O O   . LYS B 2 159 ? 158.416 168.736 69.326  1.00 140.90 ? 159 LYS D O   1 
ATOM   3672 C CB  . LYS B 2 159 ? 158.893 171.932 68.910  1.00 141.49 ? 159 LYS D CB  1 
ATOM   3673 C CG  . LYS B 2 159 ? 158.450 173.315 68.460  1.00 141.62 ? 159 LYS D CG  1 
ATOM   3674 C CD  . LYS B 2 159 ? 157.539 173.240 67.245  1.00 141.90 ? 159 LYS D CD  1 
ATOM   3675 C CE  . LYS B 2 159 ? 157.157 174.629 66.758  1.00 141.38 ? 159 LYS D CE  1 
ATOM   3676 N NZ  . LYS B 2 159 ? 156.336 174.579 65.517  1.00 141.04 ? 159 LYS D NZ  1 
ATOM   3677 N N   . SER B 2 160 ? 158.705 169.824 71.278  1.00 141.14 ? 160 SER D N   1 
ATOM   3678 C CA  . SER B 2 160 ? 159.294 168.660 71.932  1.00 140.61 ? 160 SER D CA  1 
ATOM   3679 C C   . SER B 2 160 ? 158.291 167.520 72.063  1.00 140.25 ? 160 SER D C   1 
ATOM   3680 O O   . SER B 2 160 ? 158.639 166.353 71.850  1.00 140.23 ? 160 SER D O   1 
ATOM   3681 C CB  . SER B 2 160 ? 159.839 169.051 73.305  1.00 139.88 ? 160 SER D CB  1 
ATOM   3682 O OG  . SER B 2 160 ? 160.189 167.904 74.059  1.00 139.87 ? 160 SER D OG  1 
ATOM   3683 N N   . THR B 2 161 ? 157.048 167.835 72.418  1.00 136.42 ? 161 THR D N   1 
ATOM   3684 C CA  . THR B 2 161 ? 156.045 166.801 72.627  1.00 135.80 ? 161 THR D CA  1 
ATOM   3685 C C   . THR B 2 161 ? 155.674 166.134 71.309  1.00 136.47 ? 161 THR D C   1 
ATOM   3686 O O   . THR B 2 161 ? 155.533 166.794 70.276  1.00 136.28 ? 161 THR D O   1 
ATOM   3687 C CB  . THR B 2 161 ? 154.797 167.391 73.281  1.00 135.76 ? 161 THR D CB  1 
ATOM   3688 O OG1 . THR B 2 161 ? 154.136 168.261 72.354  1.00 136.81 ? 161 THR D OG1 1 
ATOM   3689 C CG2 . THR B 2 161 ? 155.175 168.180 74.525  1.00 135.32 ? 161 THR D CG2 1 
ATOM   3690 N N   . SER B 2 162 ? 155.517 164.810 71.351  1.00 131.77 ? 162 SER D N   1 
ATOM   3691 C CA  . SER B 2 162 ? 155.163 164.037 70.170  1.00 131.07 ? 162 SER D CA  1 
ATOM   3692 C C   . SER B 2 162 ? 153.682 163.698 70.091  1.00 131.07 ? 162 SER D C   1 
ATOM   3693 O O   . SER B 2 162 ? 153.183 163.428 68.993  1.00 129.97 ? 162 SER D O   1 
ATOM   3694 C CB  . SER B 2 162 ? 155.978 162.739 70.123  1.00 129.29 ? 162 SER D CB  1 
ATOM   3695 O OG  . SER B 2 162 ? 157.368 163.012 70.093  1.00 128.45 ? 162 SER D OG  1 
ATOM   3696 N N   . GLY B 2 163 ? 152.972 163.702 71.217  1.00 132.35 ? 163 GLY D N   1 
ATOM   3697 C CA  . GLY B 2 163 ? 151.557 163.403 71.194  1.00 131.97 ? 163 GLY D CA  1 
ATOM   3698 C C   . GLY B 2 163 ? 150.735 164.530 70.601  1.00 132.62 ? 163 GLY D C   1 
ATOM   3699 O O   . GLY B 2 163 ? 151.154 165.687 70.538  1.00 132.17 ? 163 GLY D O   1 
ATOM   3700 N N   . GLY B 2 164 ? 149.532 164.172 70.149  1.00 129.77 ? 164 GLY D N   1 
ATOM   3701 C CA  . GLY B 2 164 ? 148.641 165.169 69.579  1.00 129.83 ? 164 GLY D CA  1 
ATOM   3702 C C   . GLY B 2 164 ? 148.192 166.202 70.594  1.00 130.01 ? 164 GLY D C   1 
ATOM   3703 O O   . GLY B 2 164 ? 148.114 167.394 70.290  1.00 128.83 ? 164 GLY D O   1 
ATOM   3704 N N   . THR B 2 165 ? 147.892 165.760 71.812  1.00 127.10 ? 165 THR D N   1 
ATOM   3705 C CA  . THR B 2 165 ? 147.464 166.654 72.880  1.00 126.05 ? 165 THR D CA  1 
ATOM   3706 C C   . THR B 2 165 ? 148.678 167.066 73.703  1.00 125.94 ? 165 THR D C   1 
ATOM   3707 O O   . THR B 2 165 ? 149.386 166.212 74.246  1.00 126.27 ? 165 THR D O   1 
ATOM   3708 C CB  . THR B 2 165 ? 146.420 165.976 73.766  1.00 126.05 ? 165 THR D CB  1 
ATOM   3709 O OG1 . THR B 2 165 ? 146.995 164.815 74.379  1.00 126.25 ? 165 THR D OG1 1 
ATOM   3710 C CG2 . THR B 2 165 ? 145.213 165.559 72.939  1.00 125.47 ? 165 THR D CG2 1 
ATOM   3711 N N   . ALA B 2 166 ? 148.916 168.371 73.793  1.00 122.93 ? 166 ALA D N   1 
ATOM   3712 C CA  . ALA B 2 166 ? 150.035 168.879 74.567  1.00 122.83 ? 166 ALA D CA  1 
ATOM   3713 C C   . ALA B 2 166 ? 149.701 168.882 76.055  1.00 123.02 ? 166 ALA D C   1 
ATOM   3714 O O   . ALA B 2 166 ? 148.543 168.748 76.461  1.00 123.12 ? 166 ALA D O   1 
ATOM   3715 C CB  . ALA B 2 166 ? 150.412 170.289 74.110  1.00 123.10 ? 166 ALA D CB  1 
ATOM   3716 N N   . ALA B 2 167 ? 150.739 169.034 76.871  1.00 118.84 ? 167 ALA D N   1 
ATOM   3717 C CA  . ALA B 2 167 ? 150.599 169.116 78.318  1.00 118.27 ? 167 ALA D CA  1 
ATOM   3718 C C   . ALA B 2 167 ? 150.880 170.540 78.772  1.00 119.76 ? 167 ALA D C   1 
ATOM   3719 O O   . ALA B 2 167 ? 151.885 171.138 78.375  1.00 119.60 ? 167 ALA D O   1 
ATOM   3720 C CB  . ALA B 2 167 ? 151.540 168.140 79.024  1.00 117.99 ? 167 ALA D CB  1 
ATOM   3721 N N   . LEU B 2 168 ? 149.987 171.078 79.596  1.00 118.70 ? 168 LEU D N   1 
ATOM   3722 C CA  . LEU B 2 168 ? 150.107 172.424 80.133  1.00 116.68 ? 168 LEU D CA  1 
ATOM   3723 C C   . LEU B 2 168 ? 150.027 172.353 81.649  1.00 116.94 ? 168 LEU D C   1 
ATOM   3724 O O   . LEU B 2 168 ? 149.202 171.618 82.200  1.00 117.43 ? 168 LEU D O   1 
ATOM   3725 C CB  . LEU B 2 168 ? 149.008 173.347 79.586  1.00 117.84 ? 168 LEU D CB  1 
ATOM   3726 C CG  . LEU B 2 168 ? 149.003 173.611 78.077  1.00 119.01 ? 168 LEU D CG  1 
ATOM   3727 C CD1 . LEU B 2 168 ? 148.291 172.504 77.316  1.00 117.91 ? 168 LEU D CD1 1 
ATOM   3728 C CD2 . LEU B 2 168 ? 148.365 174.956 77.767  1.00 119.64 ? 168 LEU D CD2 1 
ATOM   3729 N N   . GLY B 2 169 ? 150.883 173.115 82.322  1.00 110.82 ? 169 GLY D N   1 
ATOM   3730 C CA  . GLY B 2 169 ? 150.911 173.059 83.771  1.00 109.67 ? 169 GLY D CA  1 
ATOM   3731 C C   . GLY B 2 169 ? 151.511 174.307 84.374  1.00 110.50 ? 169 GLY D C   1 
ATOM   3732 O O   . GLY B 2 169 ? 151.984 175.205 83.675  1.00 111.85 ? 169 GLY D O   1 
ATOM   3733 N N   . CYS B 2 170 ? 151.470 174.350 85.703  1.00 102.79 ? 170 CYS D N   1 
ATOM   3734 C CA  . CYS B 2 170 ? 152.063 175.429 86.475  1.00 102.75 ? 170 CYS D CA  1 
ATOM   3735 C C   . CYS B 2 170 ? 152.752 174.835 87.693  1.00 101.62 ? 170 CYS D C   1 
ATOM   3736 O O   . CYS B 2 170 ? 152.355 173.781 88.196  1.00 99.24  ? 170 CYS D O   1 
ATOM   3737 C CB  . CYS B 2 170 ? 151.016 176.462 86.908  1.00 101.90 ? 170 CYS D CB  1 
ATOM   3738 N N   . LEU B 2 171 ? 153.789 175.519 88.163  1.00 100.65 ? 171 LEU D N   1 
ATOM   3739 C CA  . LEU B 2 171 ? 154.584 175.060 89.293  1.00 98.50  ? 171 LEU D CA  1 
ATOM   3740 C C   . LEU B 2 171 ? 154.372 176.005 90.467  1.00 99.19  ? 171 LEU D C   1 
ATOM   3741 O O   . LEU B 2 171 ? 154.617 177.210 90.351  1.00 101.13 ? 171 LEU D O   1 
ATOM   3742 C CB  . LEU B 2 171 ? 156.065 174.982 88.925  1.00 98.91  ? 171 LEU D CB  1 
ATOM   3743 C CG  . LEU B 2 171 ? 157.017 174.534 90.033  1.00 97.99  ? 171 LEU D CG  1 
ATOM   3744 C CD1 . LEU B 2 171 ? 156.560 173.216 90.631  1.00 96.95  ? 171 LEU D CD1 1 
ATOM   3745 C CD2 . LEU B 2 171 ? 158.434 174.420 89.503  1.00 99.48  ? 171 LEU D CD2 1 
ATOM   3746 N N   . VAL B 2 172 ? 153.921 175.455 91.590  1.00 89.61  ? 172 VAL D N   1 
ATOM   3747 C CA  . VAL B 2 172 ? 153.765 176.193 92.837  1.00 89.73  ? 172 VAL D CA  1 
ATOM   3748 C C   . VAL B 2 172 ? 154.844 175.710 93.794  1.00 88.57  ? 172 VAL D C   1 
ATOM   3749 O O   . VAL B 2 172 ? 154.998 174.502 94.013  1.00 89.06  ? 172 VAL D O   1 
ATOM   3750 C CB  . VAL B 2 172 ? 152.356 176.021 93.425  1.00 88.27  ? 172 VAL D CB  1 
ATOM   3751 C CG1 . VAL B 2 172 ? 151.980 174.559 93.510  1.00 87.98  ? 172 VAL D CG1 1 
ATOM   3752 C CG2 . VAL B 2 172 ? 152.286 176.646 94.795  1.00 88.89  ? 172 VAL D CG2 1 
ATOM   3753 N N   . LYS B 2 173 ? 155.611 176.648 94.344  1.00 84.68  ? 173 LYS D N   1 
ATOM   3754 C CA  . LYS B 2 173 ? 156.802 176.314 95.105  1.00 85.89  ? 173 LYS D CA  1 
ATOM   3755 C C   . LYS B 2 173 ? 156.854 177.102 96.406  1.00 85.08  ? 173 LYS D C   1 
ATOM   3756 O O   . LYS B 2 173 ? 156.380 178.237 96.489  1.00 87.00  ? 173 LYS D O   1 
ATOM   3757 C CB  . LYS B 2 173 ? 158.073 176.590 94.290  1.00 84.78  ? 173 LYS D CB  1 
ATOM   3758 C CG  . LYS B 2 173 ? 158.862 175.344 93.933  1.00 86.34  ? 173 LYS D CG  1 
ATOM   3759 C CD  . LYS B 2 173 ? 160.094 175.684 93.115  1.00 87.21  ? 173 LYS D CD  1 
ATOM   3760 C CE  . LYS B 2 173 ? 161.173 176.319 93.975  1.00 86.49  ? 173 LYS D CE  1 
ATOM   3761 N NZ  . LYS B 2 173 ? 161.514 175.472 95.151  1.00 86.28  ? 173 LYS D NZ  1 
ATOM   3762 N N   . ASP B 2 174 ? 157.447 176.473 97.420  1.00 80.80  ? 174 ASP D N   1 
ATOM   3763 C CA  . ASP B 2 174 ? 157.821 177.123 98.674  1.00 81.11  ? 174 ASP D CA  1 
ATOM   3764 C C   . ASP B 2 174 ? 156.609 177.711 99.402  1.00 81.35  ? 174 ASP D C   1 
ATOM   3765 O O   . ASP B 2 174 ? 156.472 178.924 99.565  1.00 82.22  ? 174 ASP D O   1 
ATOM   3766 C CB  . ASP B 2 174 ? 158.895 178.186 98.429  1.00 82.54  ? 174 ASP D CB  1 
ATOM   3767 C CG  . ASP B 2 174 ? 160.265 177.581 98.192  1.00 82.75  ? 174 ASP D CG  1 
ATOM   3768 O OD1 . ASP B 2 174 ? 160.519 176.467 98.697  1.00 79.19  ? 174 ASP D OD1 1 
ATOM   3769 O OD2 . ASP B 2 174 ? 161.089 178.215 97.501  1.00 84.30  ? 174 ASP D OD2 1 
ATOM   3770 N N   . TYR B 2 175 ? 155.724 176.819 99.836  1.00 79.86  ? 175 TYR D N   1 
ATOM   3771 C CA  . TYR B 2 175 ? 154.668 177.148 100.783 1.00 79.34  ? 175 TYR D CA  1 
ATOM   3772 C C   . TYR B 2 175 ? 154.747 176.156 101.933 1.00 79.12  ? 175 TYR D C   1 
ATOM   3773 O O   . TYR B 2 175 ? 154.770 174.942 101.707 1.00 82.06  ? 175 TYR D O   1 
ATOM   3774 C CB  . TYR B 2 175 ? 153.288 177.111 100.123 1.00 82.56  ? 175 TYR D CB  1 
ATOM   3775 C CG  . TYR B 2 175 ? 152.833 175.738 99.692  1.00 83.52  ? 175 TYR D CG  1 
ATOM   3776 C CD1 . TYR B 2 175 ? 153.208 175.213 98.465  1.00 83.17  ? 175 TYR D CD1 1 
ATOM   3777 C CD2 . TYR B 2 175 ? 152.033 174.962 100.518 1.00 81.15  ? 175 TYR D CD2 1 
ATOM   3778 C CE1 . TYR B 2 175 ? 152.796 173.958 98.075  1.00 81.21  ? 175 TYR D CE1 1 
ATOM   3779 C CE2 . TYR B 2 175 ? 151.619 173.710 100.137 1.00 79.65  ? 175 TYR D CE2 1 
ATOM   3780 C CZ  . TYR B 2 175 ? 152.002 173.213 98.916  1.00 80.44  ? 175 TYR D CZ  1 
ATOM   3781 O OH  . TYR B 2 175 ? 151.584 171.961 98.541  1.00 87.16  ? 175 TYR D OH  1 
ATOM   3782 N N   . PHE B 2 176 ? 154.825 176.662 103.155 1.00 71.77  ? 176 PHE D N   1 
ATOM   3783 C CA  . PHE B 2 176 ? 155.056 175.752 104.271 1.00 71.42  ? 176 PHE D CA  1 
ATOM   3784 C C   . PHE B 2 176 ? 153.806 175.048 104.797 1.00 74.83  ? 176 PHE D C   1 
ATOM   3785 O O   . PHE B 2 176 ? 153.847 173.829 105.007 1.00 79.91  ? 176 PHE D O   1 
ATOM   3786 C CB  . PHE B 2 176 ? 155.735 176.466 105.433 1.00 72.20  ? 176 PHE D CB  1 
ATOM   3787 C CG  . PHE B 2 176 ? 155.794 175.633 106.667 1.00 71.41  ? 176 PHE D CG  1 
ATOM   3788 C CD1 . PHE B 2 176 ? 156.488 174.438 106.667 1.00 70.33  ? 176 PHE D CD1 1 
ATOM   3789 C CD2 . PHE B 2 176 ? 155.127 176.017 107.811 1.00 73.63  ? 176 PHE D CD2 1 
ATOM   3790 C CE1 . PHE B 2 176 ? 156.531 173.657 107.789 1.00 69.82  ? 176 PHE D CE1 1 
ATOM   3791 C CE2 . PHE B 2 176 ? 155.171 175.238 108.938 1.00 73.87  ? 176 PHE D CE2 1 
ATOM   3792 C CZ  . PHE B 2 176 ? 155.871 174.057 108.927 1.00 70.93  ? 176 PHE D CZ  1 
ATOM   3793 N N   . PRO B 2 177 ? 152.685 175.750 105.057 1.00 79.23  ? 177 PRO D N   1 
ATOM   3794 C CA  . PRO B 2 177 ? 151.546 175.071 105.697 1.00 78.00  ? 177 PRO D CA  1 
ATOM   3795 C C   . PRO B 2 177 ? 150.880 174.031 104.808 1.00 79.99  ? 177 PRO D C   1 
ATOM   3796 O O   . PRO B 2 177 ? 151.366 173.724 103.715 1.00 82.07  ? 177 PRO D O   1 
ATOM   3797 C CB  . PRO B 2 177 ? 150.584 176.219 106.024 1.00 78.22  ? 177 PRO D CB  1 
ATOM   3798 C CG  . PRO B 2 177 ? 150.948 177.298 105.091 1.00 80.30  ? 177 PRO D CG  1 
ATOM   3799 C CD  . PRO B 2 177 ? 152.421 177.190 104.880 1.00 78.48  ? 177 PRO D CD  1 
ATOM   3800 N N   . GLU B 2 178 ? 149.765 173.479 105.290 1.00 82.52  ? 178 GLU D N   1 
ATOM   3801 C CA  . GLU B 2 178 ? 148.995 172.414 104.654 1.00 82.98  ? 178 GLU D CA  1 
ATOM   3802 C C   . GLU B 2 178 ? 148.781 172.676 103.166 1.00 81.27  ? 178 GLU D C   1 
ATOM   3803 O O   . GLU B 2 178 ? 148.737 173.836 102.738 1.00 79.34  ? 178 GLU D O   1 
ATOM   3804 C CB  . GLU B 2 178 ? 147.647 172.254 105.360 1.00 82.13  ? 178 GLU D CB  1 
ATOM   3805 C CG  . GLU B 2 178 ? 147.750 172.096 106.869 1.00 82.95  ? 178 GLU D CG  1 
ATOM   3806 C CD  . GLU B 2 178 ? 148.236 170.722 107.279 1.00 82.14  ? 178 GLU D CD  1 
ATOM   3807 O OE1 . GLU B 2 178 ? 148.158 169.794 106.448 1.00 81.42  ? 178 GLU D OE1 1 
ATOM   3808 O OE2 . GLU B 2 178 ? 148.688 170.569 108.432 1.00 80.83  ? 178 GLU D OE2 1 
ATOM   3809 N N   . PRO B 2 179 ? 148.640 171.626 102.355 1.00 91.05  ? 179 PRO D N   1 
ATOM   3810 C CA  . PRO B 2 179 ? 148.632 171.809 100.899 1.00 91.87  ? 179 PRO D CA  1 
ATOM   3811 C C   . PRO B 2 179 ? 147.512 172.726 100.431 1.00 92.29  ? 179 PRO D C   1 
ATOM   3812 O O   . PRO B 2 179 ? 146.470 172.862 101.076 1.00 88.81  ? 179 PRO D O   1 
ATOM   3813 C CB  . PRO B 2 179 ? 148.447 170.384 100.364 1.00 91.11  ? 179 PRO D CB  1 
ATOM   3814 C CG  . PRO B 2 179 ? 148.981 169.507 101.450 1.00 91.45  ? 179 PRO D CG  1 
ATOM   3815 C CD  . PRO B 2 179 ? 148.621 170.201 102.731 1.00 93.23  ? 179 PRO D CD  1 
ATOM   3816 N N   . VAL B 2 180 ? 147.755 173.365 99.294  1.00 99.19  ? 180 VAL D N   1 
ATOM   3817 C CA  . VAL B 2 180 ? 146.864 174.368 98.756  1.00 97.02  ? 180 VAL D CA  1 
ATOM   3818 C C   . VAL B 2 180 ? 145.959 173.730 97.708  1.00 99.31  ? 180 VAL D C   1 
ATOM   3819 O O   . VAL B 2 180 ? 146.206 172.628 97.226  1.00 99.06  ? 180 VAL D O   1 
ATOM   3820 C CB  . VAL B 2 180 ? 147.646 175.558 98.161  1.00 97.86  ? 180 VAL D CB  1 
ATOM   3821 C CG1 . VAL B 2 180 ? 148.786 175.941 99.082  1.00 99.82  ? 180 VAL D CG1 1 
ATOM   3822 C CG2 . VAL B 2 180 ? 148.165 175.212 96.776  1.00 96.50  ? 180 VAL D CG2 1 
ATOM   3823 N N   . THR B 2 181 ? 144.891 174.435 97.351  1.00 114.07 ? 181 THR D N   1 
ATOM   3824 C CA  . THR B 2 181 ? 143.953 173.981 96.335  1.00 114.28 ? 181 THR D CA  1 
ATOM   3825 C C   . THR B 2 181 ? 144.246 174.698 95.024  1.00 113.51 ? 181 THR D C   1 
ATOM   3826 O O   . THR B 2 181 ? 144.296 175.931 94.983  1.00 113.92 ? 181 THR D O   1 
ATOM   3827 C CB  . THR B 2 181 ? 142.509 174.243 96.763  1.00 114.45 ? 181 THR D CB  1 
ATOM   3828 O OG1 . THR B 2 181 ? 142.285 175.656 96.854  1.00 115.25 ? 181 THR D OG1 1 
ATOM   3829 C CG2 . THR B 2 181 ? 142.229 173.602 98.115  1.00 113.09 ? 181 THR D CG2 1 
ATOM   3830 N N   . VAL B 2 182 ? 144.437 173.925 93.961  1.00 108.83 ? 182 VAL D N   1 
ATOM   3831 C CA  . VAL B 2 182 ? 144.705 174.471 92.638  1.00 109.22 ? 182 VAL D CA  1 
ATOM   3832 C C   . VAL B 2 182 ? 143.537 174.127 91.727  1.00 109.90 ? 182 VAL D C   1 
ATOM   3833 O O   . VAL B 2 182 ? 142.839 173.124 91.922  1.00 109.69 ? 182 VAL D O   1 
ATOM   3834 C CB  . VAL B 2 182 ? 146.038 173.950 92.058  1.00 108.80 ? 182 VAL D CB  1 
ATOM   3835 C CG1 . VAL B 2 182 ? 145.851 172.580 91.439  1.00 108.64 ? 182 VAL D CG1 1 
ATOM   3836 C CG2 . VAL B 2 182 ? 146.598 174.931 91.039  1.00 108.72 ? 182 VAL D CG2 1 
ATOM   3837 N N   . SER B 2 183 ? 143.312 174.984 90.734  1.00 119.21 ? 183 SER D N   1 
ATOM   3838 C CA  . SER B 2 183 ? 142.216 174.800 89.797  1.00 119.21 ? 183 SER D CA  1 
ATOM   3839 C C   . SER B 2 183 ? 142.572 175.477 88.483  1.00 118.63 ? 183 SER D C   1 
ATOM   3840 O O   . SER B 2 183 ? 143.429 176.363 88.430  1.00 118.47 ? 183 SER D O   1 
ATOM   3841 C CB  . SER B 2 183 ? 140.904 175.361 90.354  1.00 119.37 ? 183 SER D CB  1 
ATOM   3842 O OG  . SER B 2 183 ? 141.054 176.721 90.721  1.00 120.20 ? 183 SER D OG  1 
ATOM   3843 N N   . TRP B 2 184 ? 141.902 175.047 87.419  1.00 120.49 ? 184 TRP D N   1 
ATOM   3844 C CA  . TRP B 2 184 ? 142.114 175.587 86.082  1.00 121.46 ? 184 TRP D CA  1 
ATOM   3845 C C   . TRP B 2 184 ? 140.800 176.153 85.568  1.00 121.50 ? 184 TRP D C   1 
ATOM   3846 O O   . TRP B 2 184 ? 139.807 175.424 85.465  1.00 121.44 ? 184 TRP D O   1 
ATOM   3847 C CB  . TRP B 2 184 ? 142.652 174.512 85.137  1.00 122.60 ? 184 TRP D CB  1 
ATOM   3848 C CG  . TRP B 2 184 ? 144.071 174.128 85.423  1.00 122.99 ? 184 TRP D CG  1 
ATOM   3849 C CD1 . TRP B 2 184 ? 144.532 173.448 86.512  1.00 121.78 ? 184 TRP D CD1 1 
ATOM   3850 C CD2 . TRP B 2 184 ? 145.215 174.402 84.608  1.00 122.45 ? 184 TRP D CD2 1 
ATOM   3851 N NE1 . TRP B 2 184 ? 145.892 173.283 86.425  1.00 120.50 ? 184 TRP D NE1 1 
ATOM   3852 C CE2 . TRP B 2 184 ? 146.335 173.860 85.265  1.00 120.83 ? 184 TRP D CE2 1 
ATOM   3853 C CE3 . TRP B 2 184 ? 145.400 175.054 83.385  1.00 122.29 ? 184 TRP D CE3 1 
ATOM   3854 C CZ2 . TRP B 2 184 ? 147.622 173.949 84.741  1.00 120.68 ? 184 TRP D CZ2 1 
ATOM   3855 C CZ3 . TRP B 2 184 ? 146.678 175.141 82.868  1.00 121.93 ? 184 TRP D CZ3 1 
ATOM   3856 C CH2 . TRP B 2 184 ? 147.771 174.592 83.544  1.00 121.59 ? 184 TRP D CH2 1 
ATOM   3857 N N   . ASN B 2 185 ? 140.801 177.447 85.244  1.00 120.72 ? 185 ASN D N   1 
ATOM   3858 C CA  . ASN B 2 185 ? 139.611 178.149 84.760  1.00 120.01 ? 185 ASN D CA  1 
ATOM   3859 C C   . ASN B 2 185 ? 138.446 178.010 85.738  1.00 120.49 ? 185 ASN D C   1 
ATOM   3860 O O   . ASN B 2 185 ? 137.291 177.856 85.336  1.00 120.88 ? 185 ASN D O   1 
ATOM   3861 C CB  . ASN B 2 185 ? 139.211 177.663 83.365  1.00 119.99 ? 185 ASN D CB  1 
ATOM   3862 N N   . SER B 2 186 ? 138.756 178.074 87.035  1.00 120.41 ? 186 SER D N   1 
ATOM   3863 C CA  . SER B 2 186 ? 137.754 177.970 88.098  1.00 120.69 ? 186 SER D CA  1 
ATOM   3864 C C   . SER B 2 186 ? 136.931 176.690 87.970  1.00 120.21 ? 186 SER D C   1 
ATOM   3865 O O   . SER B 2 186 ? 135.709 176.696 88.125  1.00 119.94 ? 186 SER D O   1 
ATOM   3866 C CB  . SER B 2 186 ? 136.844 179.201 88.122  1.00 120.15 ? 186 SER D CB  1 
ATOM   3867 O OG  . SER B 2 186 ? 135.834 179.069 89.107  1.00 120.53 ? 186 SER D OG  1 
ATOM   3868 N N   . GLY B 2 187 ? 137.608 175.580 87.682  1.00 121.73 ? 187 GLY D N   1 
ATOM   3869 C CA  . GLY B 2 187 ? 136.954 174.297 87.555  1.00 122.45 ? 187 GLY D CA  1 
ATOM   3870 C C   . GLY B 2 187 ? 136.330 174.015 86.207  1.00 123.17 ? 187 GLY D C   1 
ATOM   3871 O O   . GLY B 2 187 ? 135.706 172.959 86.043  1.00 122.43 ? 187 GLY D O   1 
ATOM   3872 N N   . ALA B 2 188 ? 136.473 174.918 85.238  1.00 124.35 ? 188 ALA D N   1 
ATOM   3873 C CA  . ALA B 2 188 ? 135.909 174.702 83.912  1.00 123.55 ? 188 ALA D CA  1 
ATOM   3874 C C   . ALA B 2 188 ? 136.761 173.785 83.046  1.00 124.00 ? 188 ALA D C   1 
ATOM   3875 O O   . ALA B 2 188 ? 136.312 173.395 81.963  1.00 124.26 ? 188 ALA D O   1 
ATOM   3876 C CB  . ALA B 2 188 ? 135.711 176.040 83.197  1.00 122.51 ? 188 ALA D CB  1 
ATOM   3877 N N   . LEU B 2 189 ? 137.966 173.434 83.487  1.00 125.24 ? 189 LEU D N   1 
ATOM   3878 C CA  . LEU B 2 189 ? 138.866 172.570 82.731  1.00 124.73 ? 189 LEU D CA  1 
ATOM   3879 C C   . LEU B 2 189 ? 138.921 171.209 83.413  1.00 124.14 ? 189 LEU D C   1 
ATOM   3880 O O   . LEU B 2 189 ? 139.563 171.057 84.458  1.00 123.17 ? 189 LEU D O   1 
ATOM   3881 C CB  . LEU B 2 189 ? 140.260 173.185 82.627  1.00 124.38 ? 189 LEU D CB  1 
ATOM   3882 C CG  . LEU B 2 189 ? 140.387 174.536 81.919  1.00 124.77 ? 189 LEU D CG  1 
ATOM   3883 C CD1 . LEU B 2 189 ? 141.804 174.734 81.407  1.00 125.11 ? 189 LEU D CD1 1 
ATOM   3884 C CD2 . LEU B 2 189 ? 139.382 174.663 80.785  1.00 124.25 ? 189 LEU D CD2 1 
ATOM   3885 N N   . THR B 2 190 ? 138.249 170.222 82.822  1.00 124.56 ? 190 THR D N   1 
ATOM   3886 C CA  . THR B 2 190 ? 138.281 168.837 83.295  1.00 124.47 ? 190 THR D CA  1 
ATOM   3887 C C   . THR B 2 190 ? 138.692 167.967 82.112  1.00 123.82 ? 190 THR D C   1 
ATOM   3888 O O   . THR B 2 190 ? 137.844 167.403 81.416  1.00 123.99 ? 190 THR D O   1 
ATOM   3889 C CB  . THR B 2 190 ? 136.934 168.413 83.871  1.00 124.17 ? 190 THR D CB  1 
ATOM   3890 O OG1 . THR B 2 190 ? 135.881 168.864 83.009  1.00 124.19 ? 190 THR D OG1 1 
ATOM   3891 C CG2 . THR B 2 190 ? 136.743 169.003 85.261  1.00 123.35 ? 190 THR D CG2 1 
ATOM   3892 N N   . SER B 2 191 ? 140.004 167.861 81.890  1.00 119.58 ? 191 SER D N   1 
ATOM   3893 C CA  . SER B 2 191 ? 140.545 167.074 80.790  1.00 120.66 ? 191 SER D CA  1 
ATOM   3894 C C   . SER B 2 191 ? 141.730 166.233 81.248  1.00 120.78 ? 191 SER D C   1 
ATOM   3895 O O   . SER B 2 191 ? 142.702 166.064 80.503  1.00 121.59 ? 191 SER D O   1 
ATOM   3896 C CB  . SER B 2 191 ? 140.957 167.972 79.622  1.00 119.47 ? 191 SER D CB  1 
ATOM   3897 O OG  . SER B 2 191 ? 141.520 167.210 78.568  1.00 119.01 ? 191 SER D OG  1 
ATOM   3898 N N   . GLY B 2 192 ? 141.667 165.703 82.465  1.00 112.22 ? 192 GLY D N   1 
ATOM   3899 C CA  . GLY B 2 192 ? 142.763 164.927 83.006  1.00 110.30 ? 192 GLY D CA  1 
ATOM   3900 C C   . GLY B 2 192 ? 143.734 165.772 83.802  1.00 109.90 ? 192 GLY D C   1 
ATOM   3901 O O   . GLY B 2 192 ? 144.943 165.733 83.562  1.00 111.06 ? 192 GLY D O   1 
ATOM   3902 N N   . VAL B 2 193 ? 143.213 166.546 84.752  1.00 103.39 ? 193 VAL D N   1 
ATOM   3903 C CA  . VAL B 2 193 ? 144.065 167.362 85.610  1.00 105.21 ? 193 VAL D CA  1 
ATOM   3904 C C   . VAL B 2 193 ? 144.795 166.448 86.585  1.00 106.32 ? 193 VAL D C   1 
ATOM   3905 O O   . VAL B 2 193 ? 144.172 165.664 87.310  1.00 105.09 ? 193 VAL D O   1 
ATOM   3906 C CB  . VAL B 2 193 ? 143.243 168.425 86.349  1.00 104.59 ? 193 VAL D CB  1 
ATOM   3907 C CG1 . VAL B 2 193 ? 144.089 169.107 87.412  1.00 104.46 ? 193 VAL D CG1 1 
ATOM   3908 C CG2 . VAL B 2 193 ? 142.695 169.449 85.368  1.00 103.76 ? 193 VAL D CG2 1 
ATOM   3909 N N   . HIS B 2 194 ? 146.121 166.547 86.607  1.00 101.96 ? 194 HIS D N   1 
ATOM   3910 C CA  . HIS B 2 194 ? 146.968 165.696 87.438  1.00 100.36 ? 194 HIS D CA  1 
ATOM   3911 C C   . HIS B 2 194 ? 147.695 166.580 88.444  1.00 97.49  ? 194 HIS D C   1 
ATOM   3912 O O   . HIS B 2 194 ? 148.735 167.166 88.131  1.00 98.34  ? 194 HIS D O   1 
ATOM   3913 C CB  . HIS B 2 194 ? 147.949 164.907 86.576  1.00 99.31  ? 194 HIS D CB  1 
ATOM   3914 C CG  . HIS B 2 194 ? 147.436 163.566 86.157  1.00 99.33  ? 194 HIS D CG  1 
ATOM   3915 N ND1 . HIS B 2 194 ? 146.537 162.843 86.911  1.00 97.51  ? 194 HIS D ND1 1 
ATOM   3916 C CD2 . HIS B 2 194 ? 147.688 162.820 85.055  1.00 99.01  ? 194 HIS D CD2 1 
ATOM   3917 C CE1 . HIS B 2 194 ? 146.263 161.707 86.296  1.00 98.88  ? 194 HIS D CE1 1 
ATOM   3918 N NE2 . HIS B 2 194 ? 146.949 161.668 85.168  1.00 100.84 ? 194 HIS D NE2 1 
ATOM   3919 N N   . THR B 2 195 ? 147.146 166.673 89.652  1.00 90.79  ? 195 THR D N   1 
ATOM   3920 C CA  . THR B 2 195 ? 147.751 167.441 90.734  1.00 92.87  ? 195 THR D CA  1 
ATOM   3921 C C   . THR B 2 195 ? 148.545 166.470 91.603  1.00 91.51  ? 195 THR D C   1 
ATOM   3922 O O   . THR B 2 195 ? 147.965 165.651 92.324  1.00 91.22  ? 195 THR D O   1 
ATOM   3923 C CB  . THR B 2 195 ? 146.688 168.182 91.543  1.00 94.84  ? 195 THR D CB  1 
ATOM   3924 O OG1 . THR B 2 195 ? 146.331 169.389 90.860  1.00 93.95  ? 195 THR D OG1 1 
ATOM   3925 C CG2 . THR B 2 195 ? 147.218 168.552 92.921  1.00 92.97  ? 195 THR D CG2 1 
ATOM   3926 N N   . PHE B 2 196 ? 149.869 166.547 91.512  1.00 86.01  ? 196 PHE D N   1 
ATOM   3927 C CA  . PHE B 2 196 ? 150.719 165.624 92.239  1.00 84.23  ? 196 PHE D CA  1 
ATOM   3928 C C   . PHE B 2 196 ? 150.739 165.976 93.725  1.00 86.33  ? 196 PHE D C   1 
ATOM   3929 O O   . PHE B 2 196 ? 150.550 167.136 94.098  1.00 90.86  ? 196 PHE D O   1 
ATOM   3930 C CB  . PHE B 2 196 ? 152.137 165.653 91.678  1.00 84.31  ? 196 PHE D CB  1 
ATOM   3931 C CG  . PHE B 2 196 ? 152.210 165.352 90.211  1.00 87.49  ? 196 PHE D CG  1 
ATOM   3932 C CD1 . PHE B 2 196 ? 152.313 164.049 89.764  1.00 87.77  ? 196 PHE D CD1 1 
ATOM   3933 C CD2 . PHE B 2 196 ? 152.170 166.373 89.278  1.00 88.19  ? 196 PHE D CD2 1 
ATOM   3934 C CE1 . PHE B 2 196 ? 152.378 163.770 88.414  1.00 86.67  ? 196 PHE D CE1 1 
ATOM   3935 C CE2 . PHE B 2 196 ? 152.232 166.100 87.929  1.00 87.88  ? 196 PHE D CE2 1 
ATOM   3936 C CZ  . PHE B 2 196 ? 152.336 164.797 87.496  1.00 87.42  ? 196 PHE D CZ  1 
ATOM   3937 N N   . PRO B 2 197 ? 150.951 164.989 94.593  1.00 77.40  ? 197 PRO D N   1 
ATOM   3938 C CA  . PRO B 2 197 ? 151.052 165.281 96.025  1.00 76.34  ? 197 PRO D CA  1 
ATOM   3939 C C   . PRO B 2 197 ? 152.217 166.212 96.318  1.00 77.66  ? 197 PRO D C   1 
ATOM   3940 O O   . PRO B 2 197 ? 153.242 166.197 95.633  1.00 79.96  ? 197 PRO D O   1 
ATOM   3941 C CB  . PRO B 2 197 ? 151.266 163.901 96.656  1.00 79.54  ? 197 PRO D CB  1 
ATOM   3942 C CG  . PRO B 2 197 ? 150.702 162.946 95.666  1.00 79.11  ? 197 PRO D CG  1 
ATOM   3943 C CD  . PRO B 2 197 ? 150.977 163.543 94.322  1.00 81.35  ? 197 PRO D CD  1 
ATOM   3944 N N   . ALA B 2 198 ? 152.042 167.038 97.344  1.00 73.99  ? 198 ALA D N   1 
ATOM   3945 C CA  . ALA B 2 198 ? 153.083 167.976 97.735  1.00 71.98  ? 198 ALA D CA  1 
ATOM   3946 C C   . ALA B 2 198 ? 154.317 167.232 98.223  1.00 72.06  ? 198 ALA D C   1 
ATOM   3947 O O   . ALA B 2 198 ? 154.218 166.191 98.875  1.00 75.83  ? 198 ALA D O   1 
ATOM   3948 C CB  . ALA B 2 198 ? 152.571 168.912 98.825  1.00 73.95  ? 198 ALA D CB  1 
ATOM   3949 N N   . VAL B 2 199 ? 155.488 167.771 97.898  1.00 75.77  ? 199 VAL D N   1 
ATOM   3950 C CA  . VAL B 2 199 ? 156.761 167.201 98.317  1.00 77.60  ? 199 VAL D CA  1 
ATOM   3951 C C   . VAL B 2 199 ? 157.456 168.192 99.238  1.00 77.50  ? 199 VAL D C   1 
ATOM   3952 O O   . VAL B 2 199 ? 157.369 169.409 99.041  1.00 77.51  ? 199 VAL D O   1 
ATOM   3953 C CB  . VAL B 2 199 ? 157.654 166.834 97.112  1.00 78.59  ? 199 VAL D CB  1 
ATOM   3954 C CG1 . VAL B 2 199 ? 156.858 166.050 96.091  1.00 78.23  ? 199 VAL D CG1 1 
ATOM   3955 C CG2 . VAL B 2 199 ? 158.253 168.076 96.468  1.00 78.22  ? 199 VAL D CG2 1 
ATOM   3956 N N   . LEU B 2 200 ? 158.116 167.669 100.266 1.00 79.05  ? 200 LEU D N   1 
ATOM   3957 C CA  . LEU B 2 200 ? 158.850 168.488 101.222 1.00 78.66  ? 200 LEU D CA  1 
ATOM   3958 C C   . LEU B 2 200 ? 160.288 168.619 100.738 1.00 80.35  ? 200 LEU D C   1 
ATOM   3959 O O   . LEU B 2 200 ? 161.028 167.631 100.693 1.00 82.57  ? 200 LEU D O   1 
ATOM   3960 C CB  . LEU B 2 200 ? 158.789 167.871 102.617 1.00 77.80  ? 200 LEU D CB  1 
ATOM   3961 C CG  . LEU B 2 200 ? 159.419 168.674 103.754 1.00 80.72  ? 200 LEU D CG  1 
ATOM   3962 C CD1 . LEU B 2 200 ? 158.383 169.541 104.441 1.00 81.44  ? 200 LEU D CD1 1 
ATOM   3963 C CD2 . LEU B 2 200 ? 160.091 167.746 104.754 1.00 80.40  ? 200 LEU D CD2 1 
ATOM   3964 N N   . GLN B 2 201 ? 160.684 169.834 100.372 1.00 87.69  ? 201 GLN D N   1 
ATOM   3965 C CA  . GLN B 2 201 ? 162.033 170.080 99.893  1.00 88.09  ? 201 GLN D CA  1 
ATOM   3966 C C   . GLN B 2 201 ? 163.004 170.164 101.070 1.00 89.21  ? 201 GLN D C   1 
ATOM   3967 O O   . GLN B 2 201 ? 162.620 170.077 102.239 1.00 86.33  ? 201 GLN D O   1 
ATOM   3968 C CB  . GLN B 2 201 ? 162.073 171.351 99.048  1.00 87.21  ? 201 GLN D CB  1 
ATOM   3969 C CG  . GLN B 2 201 ? 160.969 171.435 98.008  1.00 87.82  ? 201 GLN D CG  1 
ATOM   3970 C CD  . GLN B 2 201 ? 160.689 172.856 97.567  1.00 88.22  ? 201 GLN D CD  1 
ATOM   3971 O OE1 . GLN B 2 201 ? 161.024 173.249 96.450  1.00 87.53  ? 201 GLN D OE1 1 
ATOM   3972 N NE2 . GLN B 2 201 ? 160.068 173.637 98.442  1.00 87.41  ? 201 GLN D NE2 1 
ATOM   3973 N N   . SER B 2 202 ? 164.289 170.334 100.752 1.00 99.79  ? 202 SER D N   1 
ATOM   3974 C CA  . SER B 2 202 ? 165.309 170.392 101.794 1.00 99.62  ? 202 SER D CA  1 
ATOM   3975 C C   . SER B 2 202 ? 165.170 171.639 102.656 1.00 98.66  ? 202 SER D C   1 
ATOM   3976 O O   . SER B 2 202 ? 165.520 171.613 103.842 1.00 98.60  ? 202 SER D O   1 
ATOM   3977 C CB  . SER B 2 202 ? 166.701 170.336 101.167 1.00 98.70  ? 202 SER D CB  1 
ATOM   3978 O OG  . SER B 2 202 ? 166.923 171.456 100.328 1.00 99.18  ? 202 SER D OG  1 
ATOM   3979 N N   . SER B 2 203 ? 164.664 172.732 102.090 1.00 93.46  ? 203 SER D N   1 
ATOM   3980 C CA  . SER B 2 203 ? 164.534 173.984 102.823 1.00 93.33  ? 203 SER D CA  1 
ATOM   3981 C C   . SER B 2 203 ? 163.342 173.999 103.770 1.00 92.77  ? 203 SER D C   1 
ATOM   3982 O O   . SER B 2 203 ? 163.184 174.967 104.521 1.00 92.18  ? 203 SER D O   1 
ATOM   3983 C CB  . SER B 2 203 ? 164.434 175.157 101.845 1.00 93.35  ? 203 SER D CB  1 
ATOM   3984 O OG  . SER B 2 203 ? 163.427 174.932 100.877 1.00 95.81  ? 203 SER D OG  1 
ATOM   3985 N N   . GLY B 2 204 ? 162.505 172.965 103.755 1.00 88.57  ? 204 GLY D N   1 
ATOM   3986 C CA  . GLY B 2 204 ? 161.391 172.874 104.673 1.00 88.14  ? 204 GLY D CA  1 
ATOM   3987 C C   . GLY B 2 204 ? 160.076 173.420 104.167 1.00 88.52  ? 204 GLY D C   1 
ATOM   3988 O O   . GLY B 2 204 ? 159.164 173.632 104.974 1.00 89.50  ? 204 GLY D O   1 
ATOM   3989 N N   . LEU B 2 205 ? 159.944 173.655 102.866 1.00 81.49  ? 205 LEU D N   1 
ATOM   3990 C CA  . LEU B 2 205 ? 158.723 174.192 102.284 1.00 78.30  ? 205 LEU D CA  1 
ATOM   3991 C C   . LEU B 2 205 ? 158.166 173.215 101.259 1.00 79.23  ? 205 LEU D C   1 
ATOM   3992 O O   . LEU B 2 205 ? 158.918 172.620 100.482 1.00 81.92  ? 205 LEU D O   1 
ATOM   3993 C CB  . LEU B 2 205 ? 158.964 175.555 101.625 1.00 81.39  ? 205 LEU D CB  1 
ATOM   3994 C CG  . LEU B 2 205 ? 159.595 176.700 102.427 1.00 81.89  ? 205 LEU D CG  1 
ATOM   3995 C CD1 . LEU B 2 205 ? 159.005 176.782 103.828 1.00 82.15  ? 205 LEU D CD1 1 
ATOM   3996 C CD2 . LEU B 2 205 ? 161.116 176.604 102.472 1.00 82.17  ? 205 LEU D CD2 1 
ATOM   3997 N N   . TYR B 2 206 ? 156.846 173.060 101.260 1.00 80.44  ? 206 TYR D N   1 
ATOM   3998 C CA  . TYR B 2 206 ? 156.194 172.128 100.356 1.00 79.61  ? 206 TYR D CA  1 
ATOM   3999 C C   . TYR B 2 206 ? 156.185 172.677 98.931  1.00 78.42  ? 206 TYR D C   1 
ATOM   4000 O O   . TYR B 2 206 ? 156.432 173.860 98.684  1.00 80.82  ? 206 TYR D O   1 
ATOM   4001 C CB  . TYR B 2 206 ? 154.765 171.842 100.818 1.00 76.85  ? 206 TYR D CB  1 
ATOM   4002 C CG  . TYR B 2 206 ? 154.680 170.940 102.024 1.00 74.62  ? 206 TYR D CG  1 
ATOM   4003 C CD1 . TYR B 2 206 ? 155.052 171.392 103.278 1.00 73.96  ? 206 TYR D CD1 1 
ATOM   4004 C CD2 . TYR B 2 206 ? 154.235 169.633 101.907 1.00 77.84  ? 206 TYR D CD2 1 
ATOM   4005 C CE1 . TYR B 2 206 ? 154.980 170.573 104.381 1.00 77.41  ? 206 TYR D CE1 1 
ATOM   4006 C CE2 . TYR B 2 206 ? 154.160 168.805 103.006 1.00 77.45  ? 206 TYR D CE2 1 
ATOM   4007 C CZ  . TYR B 2 206 ? 154.534 169.280 104.240 1.00 79.25  ? 206 TYR D CZ  1 
ATOM   4008 O OH  . TYR B 2 206 ? 154.463 168.460 105.341 1.00 81.69  ? 206 TYR D OH  1 
ATOM   4009 N N   . SER B 2 207 ? 155.899 171.787 97.984  1.00 78.99  ? 207 SER D N   1 
ATOM   4010 C CA  . SER B 2 207 ? 155.784 172.155 96.581  1.00 77.33  ? 207 SER D CA  1 
ATOM   4011 C C   . SER B 2 207 ? 155.029 171.056 95.854  1.00 77.46  ? 207 SER D C   1 
ATOM   4012 O O   . SER B 2 207 ? 155.196 169.875 96.163  1.00 81.85  ? 207 SER D O   1 
ATOM   4013 C CB  . SER B 2 207 ? 157.159 172.364 95.939  1.00 78.21  ? 207 SER D CB  1 
ATOM   4014 O OG  . SER B 2 207 ? 157.813 173.495 96.483  1.00 82.10  ? 207 SER D OG  1 
ATOM   4015 N N   . LEU B 2 208 ? 154.200 171.449 94.893  1.00 76.51  ? 208 LEU D N   1 
ATOM   4016 C CA  . LEU B 2 208 ? 153.501 170.496 94.047  1.00 79.82  ? 208 LEU D CA  1 
ATOM   4017 C C   . LEU B 2 208 ? 153.441 171.046 92.631  1.00 82.13  ? 208 LEU D C   1 
ATOM   4018 O O   . LEU B 2 208 ? 153.829 172.186 92.365  1.00 84.27  ? 208 LEU D O   1 
ATOM   4019 C CB  . LEU B 2 208 ? 152.093 170.182 94.580  1.00 82.52  ? 208 LEU D CB  1 
ATOM   4020 C CG  . LEU B 2 208 ? 151.015 171.269 94.638  1.00 79.35  ? 208 LEU D CG  1 
ATOM   4021 C CD1 . LEU B 2 208 ? 150.162 171.274 93.381  1.00 80.48  ? 208 LEU D CD1 1 
ATOM   4022 C CD2 . LEU B 2 208 ? 150.138 171.066 95.859  1.00 77.33  ? 208 LEU D CD2 1 
ATOM   4023 N N   . SER B 2 209 ? 152.960 170.212 91.716  1.00 85.02  ? 209 SER D N   1 
ATOM   4024 C CA  . SER B 2 209 ? 152.772 170.592 90.326  1.00 83.52  ? 209 SER D CA  1 
ATOM   4025 C C   . SER B 2 209 ? 151.418 170.089 89.856  1.00 84.42  ? 209 SER D C   1 
ATOM   4026 O O   . SER B 2 209 ? 150.891 169.103 90.378  1.00 86.37  ? 209 SER D O   1 
ATOM   4027 C CB  . SER B 2 209 ? 153.886 170.032 89.435  1.00 86.36  ? 209 SER D CB  1 
ATOM   4028 O OG  . SER B 2 209 ? 155.159 170.245 90.019  1.00 85.36  ? 209 SER D OG  1 
ATOM   4029 N N   . SER B 2 210 ? 150.854 170.776 88.866  1.00 92.81  ? 210 SER D N   1 
ATOM   4030 C CA  . SER B 2 210 ? 149.526 170.443 88.357  1.00 96.10  ? 210 SER D CA  1 
ATOM   4031 C C   . SER B 2 210 ? 149.531 170.597 86.843  1.00 96.20  ? 210 SER D C   1 
ATOM   4032 O O   . SER B 2 210 ? 149.533 171.720 86.332  1.00 95.04  ? 210 SER D O   1 
ATOM   4033 C CB  . SER B 2 210 ? 148.456 171.327 88.993  1.00 96.55  ? 210 SER D CB  1 
ATOM   4034 O OG  . SER B 2 210 ? 148.499 171.220 90.404  1.00 95.64  ? 210 SER D OG  1 
ATOM   4035 N N   . VAL B 2 211 ? 149.525 169.473 86.135  1.00 100.80 ? 211 VAL D N   1 
ATOM   4036 C CA  . VAL B 2 211 ? 149.526 169.464 84.681  1.00 101.84 ? 211 VAL D CA  1 
ATOM   4037 C C   . VAL B 2 211 ? 148.194 168.911 84.194  1.00 100.74 ? 211 VAL D C   1 
ATOM   4038 O O   . VAL B 2 211 ? 147.474 168.213 84.915  1.00 97.88  ? 211 VAL D O   1 
ATOM   4039 C CB  . VAL B 2 211 ? 150.705 168.648 84.108  1.00 101.46 ? 211 VAL D CB  1 
ATOM   4040 C CG1 . VAL B 2 211 ? 151.981 168.944 84.881  1.00 98.79  ? 211 VAL D CG1 1 
ATOM   4041 C CG2 . VAL B 2 211 ? 150.390 167.163 84.142  1.00 102.30 ? 211 VAL D CG2 1 
ATOM   4042 N N   . VAL B 2 212 ? 147.862 169.239 82.949  1.00 110.07 ? 212 VAL D N   1 
ATOM   4043 C CA  . VAL B 2 212 ? 146.612 168.796 82.343  1.00 110.91 ? 212 VAL D CA  1 
ATOM   4044 C C   . VAL B 2 212 ? 146.853 168.549 80.861  1.00 111.06 ? 212 VAL D C   1 
ATOM   4045 O O   . VAL B 2 212 ? 147.589 169.292 80.205  1.00 109.40 ? 212 VAL D O   1 
ATOM   4046 C CB  . VAL B 2 212 ? 145.480 169.824 82.574  1.00 112.93 ? 212 VAL D CB  1 
ATOM   4047 C CG1 . VAL B 2 212 ? 145.865 171.186 82.015  1.00 112.47 ? 212 VAL D CG1 1 
ATOM   4048 C CG2 . VAL B 2 212 ? 144.170 169.337 81.966  1.00 112.92 ? 212 VAL D CG2 1 
ATOM   4049 N N   . THR B 2 213 ? 146.244 167.486 80.340  1.00 119.17 ? 213 THR D N   1 
ATOM   4050 C CA  . THR B 2 213 ? 146.290 167.207 78.912  1.00 119.25 ? 213 THR D CA  1 
ATOM   4051 C C   . THR B 2 213 ? 145.217 168.020 78.203  1.00 119.40 ? 213 THR D C   1 
ATOM   4052 O O   . THR B 2 213 ? 144.046 167.995 78.596  1.00 118.97 ? 213 THR D O   1 
ATOM   4053 C CB  . THR B 2 213 ? 146.086 165.717 78.641  1.00 118.81 ? 213 THR D CB  1 
ATOM   4054 O OG1 . THR B 2 213 ? 144.888 165.271 79.289  1.00 118.42 ? 213 THR D OG1 1 
ATOM   4055 C CG2 . THR B 2 213 ? 147.269 164.913 79.158  1.00 119.39 ? 213 THR D CG2 1 
ATOM   4056 N N   . VAL B 2 214 ? 145.616 168.744 77.163  1.00 126.66 ? 214 VAL D N   1 
ATOM   4057 C CA  . VAL B 2 214 ? 144.698 169.615 76.434  1.00 126.94 ? 214 VAL D CA  1 
ATOM   4058 C C   . VAL B 2 214 ? 144.799 169.316 74.944  1.00 127.03 ? 214 VAL D C   1 
ATOM   4059 O O   . VAL B 2 214 ? 145.913 169.204 74.410  1.00 127.38 ? 214 VAL D O   1 
ATOM   4060 C CB  . VAL B 2 214 ? 144.993 171.095 76.725  1.00 127.57 ? 214 VAL D CB  1 
ATOM   4061 C CG1 . VAL B 2 214 ? 144.189 171.990 75.800  1.00 127.01 ? 214 VAL D CG1 1 
ATOM   4062 C CG2 . VAL B 2 214 ? 144.696 171.421 78.181  1.00 127.31 ? 214 VAL D CG2 1 
ATOM   4063 N N   . PRO B 2 215 ? 143.677 169.166 74.240  1.00 131.94 ? 215 PRO D N   1 
ATOM   4064 C CA  . PRO B 2 215 ? 143.740 168.965 72.788  1.00 132.58 ? 215 PRO D CA  1 
ATOM   4065 C C   . PRO B 2 215 ? 144.379 170.156 72.089  1.00 132.86 ? 215 PRO D C   1 
ATOM   4066 O O   . PRO B 2 215 ? 144.233 171.306 72.509  1.00 132.09 ? 215 PRO D O   1 
ATOM   4067 C CB  . PRO B 2 215 ? 142.269 168.803 72.385  1.00 132.73 ? 215 PRO D CB  1 
ATOM   4068 C CG  . PRO B 2 215 ? 141.563 168.412 73.644  1.00 132.53 ? 215 PRO D CG  1 
ATOM   4069 C CD  . PRO B 2 215 ? 142.299 169.095 74.753  1.00 131.11 ? 215 PRO D CD  1 
ATOM   4070 N N   . SER B 2 216 ? 145.097 169.862 71.004  1.00 138.77 ? 216 SER D N   1 
ATOM   4071 C CA  . SER B 2 216 ? 145.796 170.895 70.250  1.00 139.23 ? 216 SER D CA  1 
ATOM   4072 C C   . SER B 2 216 ? 144.856 171.799 69.463  1.00 139.19 ? 216 SER D C   1 
ATOM   4073 O O   . SER B 2 216 ? 145.314 172.807 68.914  1.00 139.25 ? 216 SER D O   1 
ATOM   4074 C CB  . SER B 2 216 ? 146.808 170.254 69.299  1.00 138.57 ? 216 SER D CB  1 
ATOM   4075 O OG  . SER B 2 216 ? 147.521 171.241 68.574  1.00 138.69 ? 216 SER D OG  1 
ATOM   4076 N N   . SER B 2 217 ? 143.565 171.462 69.392  1.00 138.76 ? 217 SER D N   1 
ATOM   4077 C CA  . SER B 2 217 ? 142.630 172.254 68.598  1.00 138.47 ? 217 SER D CA  1 
ATOM   4078 C C   . SER B 2 217 ? 142.504 173.676 69.132  1.00 139.15 ? 217 SER D C   1 
ATOM   4079 O O   . SER B 2 217 ? 142.445 174.635 68.354  1.00 138.71 ? 217 SER D O   1 
ATOM   4080 C CB  . SER B 2 217 ? 141.263 171.571 68.569  1.00 138.20 ? 217 SER D CB  1 
ATOM   4081 O OG  . SER B 2 217 ? 140.726 171.450 69.874  1.00 138.58 ? 217 SER D OG  1 
ATOM   4082 N N   . SER B 2 218 ? 142.458 173.834 70.452  1.00 139.92 ? 218 SER D N   1 
ATOM   4083 C CA  . SER B 2 218 ? 142.265 175.133 71.084  1.00 139.08 ? 218 SER D CA  1 
ATOM   4084 C C   . SER B 2 218 ? 143.462 175.514 71.947  1.00 138.56 ? 218 SER D C   1 
ATOM   4085 O O   . SER B 2 218 ? 143.312 176.053 73.046  1.00 138.64 ? 218 SER D O   1 
ATOM   4086 C CB  . SER B 2 218 ? 140.983 175.147 71.912  1.00 138.42 ? 218 SER D CB  1 
ATOM   4087 O OG  . SER B 2 218 ? 141.055 174.216 72.977  1.00 138.67 ? 218 SER D OG  1 
ATOM   4088 N N   . LEU B 2 219 ? 144.673 175.238 71.460  1.00 134.87 ? 219 LEU D N   1 
ATOM   4089 C CA  . LEU B 2 219 ? 145.869 175.624 72.204  1.00 135.58 ? 219 LEU D CA  1 
ATOM   4090 C C   . LEU B 2 219 ? 146.031 177.139 72.235  1.00 135.25 ? 219 LEU D C   1 
ATOM   4091 O O   . LEU B 2 219 ? 146.261 177.727 73.299  1.00 134.96 ? 219 LEU D O   1 
ATOM   4092 C CB  . LEU B 2 219 ? 147.105 174.961 71.596  1.00 135.06 ? 219 LEU D CB  1 
ATOM   4093 C CG  . LEU B 2 219 ? 147.435 173.556 72.104  1.00 134.68 ? 219 LEU D CG  1 
ATOM   4094 C CD1 . LEU B 2 219 ? 148.736 173.050 71.498  1.00 134.02 ? 219 LEU D CD1 1 
ATOM   4095 C CD2 . LEU B 2 219 ? 147.506 173.537 73.622  1.00 135.25 ? 219 LEU D CD2 1 
ATOM   4096 N N   . GLY B 2 220 ? 145.915 177.789 71.078  1.00 137.07 ? 220 GLY D N   1 
ATOM   4097 C CA  . GLY B 2 220 ? 146.047 179.229 70.995  1.00 137.08 ? 220 GLY D CA  1 
ATOM   4098 C C   . GLY B 2 220 ? 144.782 180.021 71.225  1.00 137.48 ? 220 GLY D C   1 
ATOM   4099 O O   . GLY B 2 220 ? 144.839 181.251 71.305  1.00 137.53 ? 220 GLY D O   1 
ATOM   4100 N N   . THR B 2 221 ? 143.636 179.352 71.338  1.00 140.19 ? 221 THR D N   1 
ATOM   4101 C CA  . THR B 2 221 ? 142.352 180.017 71.516  1.00 139.85 ? 221 THR D CA  1 
ATOM   4102 C C   . THR B 2 221 ? 141.821 179.908 72.936  1.00 139.58 ? 221 THR D C   1 
ATOM   4103 O O   . THR B 2 221 ? 141.489 180.925 73.553  1.00 139.51 ? 221 THR D O   1 
ATOM   4104 C CB  . THR B 2 221 ? 141.320 179.441 70.534  1.00 139.64 ? 221 THR D CB  1 
ATOM   4105 O OG1 . THR B 2 221 ? 141.797 179.593 69.191  1.00 139.32 ? 221 THR D OG1 1 
ATOM   4106 C CG2 . THR B 2 221 ? 139.987 180.160 70.678  1.00 139.47 ? 221 THR D CG2 1 
ATOM   4107 N N   . GLN B 2 222 ? 141.730 178.694 73.473  1.00 136.72 ? 222 GLN D N   1 
ATOM   4108 C CA  . GLN B 2 222 ? 141.191 178.502 74.812  1.00 136.84 ? 222 GLN D CA  1 
ATOM   4109 C C   . GLN B 2 222 ? 142.111 179.120 75.857  1.00 136.82 ? 222 GLN D C   1 
ATOM   4110 O O   . GLN B 2 222 ? 143.338 179.090 75.727  1.00 136.01 ? 222 GLN D O   1 
ATOM   4111 C CB  . GLN B 2 222 ? 140.998 177.012 75.096  1.00 136.83 ? 222 GLN D CB  1 
ATOM   4112 C CG  . GLN B 2 222 ? 140.358 176.708 76.440  1.00 136.92 ? 222 GLN D CG  1 
ATOM   4113 C CD  . GLN B 2 222 ? 140.065 175.233 76.623  1.00 137.08 ? 222 GLN D CD  1 
ATOM   4114 O OE1 . GLN B 2 222 ? 140.702 174.380 76.005  1.00 136.83 ? 222 GLN D OE1 1 
ATOM   4115 N NE2 . GLN B 2 222 ? 139.096 174.924 77.476  1.00 136.65 ? 222 GLN D NE2 1 
ATOM   4116 N N   . THR B 2 223 ? 141.508 179.695 76.893  1.00 134.93 ? 223 THR D N   1 
ATOM   4117 C CA  . THR B 2 223 ? 142.254 180.274 77.999  1.00 134.36 ? 223 THR D CA  1 
ATOM   4118 C C   . THR B 2 223 ? 142.551 179.207 79.043  1.00 134.28 ? 223 THR D C   1 
ATOM   4119 O O   . THR B 2 223 ? 141.684 178.399 79.389  1.00 134.04 ? 223 THR D O   1 
ATOM   4120 C CB  . THR B 2 223 ? 141.475 181.425 78.637  1.00 134.10 ? 223 THR D CB  1 
ATOM   4121 O OG1 . THR B 2 223 ? 140.326 180.907 79.320  1.00 134.14 ? 223 THR D OG1 1 
ATOM   4122 C CG2 . THR B 2 223 ? 141.020 182.413 77.571  1.00 134.19 ? 223 THR D CG2 1 
ATOM   4123 N N   . TYR B 2 224 ? 143.786 179.207 79.542  1.00 133.05 ? 224 TYR D N   1 
ATOM   4124 C CA  . TYR B 2 224 ? 144.238 178.260 80.561  1.00 132.76 ? 224 TYR D CA  1 
ATOM   4125 C C   . TYR B 2 224 ? 144.821 179.074 81.711  1.00 132.83 ? 224 TYR D C   1 
ATOM   4126 O O   . TYR B 2 224 ? 146.011 179.399 81.715  1.00 133.11 ? 224 TYR D O   1 
ATOM   4127 C CB  . TYR B 2 224 ? 145.250 177.275 79.987  1.00 133.06 ? 224 TYR D CB  1 
ATOM   4128 C CG  . TYR B 2 224 ? 144.821 176.668 78.671  1.00 134.11 ? 224 TYR D CG  1 
ATOM   4129 C CD1 . TYR B 2 224 ? 143.848 175.679 78.625  1.00 133.50 ? 224 TYR D CD1 1 
ATOM   4130 C CD2 . TYR B 2 224 ? 145.383 177.090 77.475  1.00 134.07 ? 224 TYR D CD2 1 
ATOM   4131 C CE1 . TYR B 2 224 ? 143.451 175.125 77.425  1.00 132.90 ? 224 TYR D CE1 1 
ATOM   4132 C CE2 . TYR B 2 224 ? 144.992 176.541 76.270  1.00 133.70 ? 224 TYR D CE2 1 
ATOM   4133 C CZ  . TYR B 2 224 ? 144.026 175.560 76.252  1.00 133.31 ? 224 TYR D CZ  1 
ATOM   4134 O OH  . TYR B 2 224 ? 143.635 175.014 75.052  1.00 133.61 ? 224 TYR D OH  1 
ATOM   4135 N N   . ILE B 2 225 ? 143.976 179.405 82.682  1.00 125.67 ? 225 ILE D N   1 
ATOM   4136 C CA  . ILE B 2 225 ? 144.361 180.206 83.837  1.00 125.73 ? 225 ILE D CA  1 
ATOM   4137 C C   . ILE B 2 225 ? 144.396 179.296 85.057  1.00 125.19 ? 225 ILE D C   1 
ATOM   4138 O O   . ILE B 2 225 ? 143.427 178.579 85.335  1.00 124.61 ? 225 ILE D O   1 
ATOM   4139 C CB  . ILE B 2 225 ? 143.399 181.390 84.046  1.00 125.97 ? 225 ILE D CB  1 
ATOM   4140 C CG1 . ILE B 2 225 ? 143.640 182.061 85.402  1.00 124.59 ? 225 ILE D CG1 1 
ATOM   4141 C CG2 . ILE B 2 225 ? 141.947 180.945 83.893  1.00 126.12 ? 225 ILE D CG2 1 
ATOM   4142 C CD1 . ILE B 2 225 ? 145.016 182.673 85.549  1.00 124.74 ? 225 ILE D CD1 1 
ATOM   4143 N N   . CYS B 2 226 ? 145.515 179.316 85.775  1.00 122.48 ? 226 CYS D N   1 
ATOM   4144 C CA  . CYS B 2 226 ? 145.703 178.498 86.966  1.00 121.80 ? 226 CYS D CA  1 
ATOM   4145 C C   . CYS B 2 226 ? 145.390 179.337 88.198  1.00 121.41 ? 226 CYS D C   1 
ATOM   4146 O O   . CYS B 2 226 ? 145.982 180.403 88.394  1.00 120.04 ? 226 CYS D O   1 
ATOM   4147 C CB  . CYS B 2 226 ? 147.128 177.950 87.033  1.00 120.91 ? 226 CYS D CB  1 
ATOM   4148 N N   . ASN B 2 227 ? 144.462 178.857 89.019  1.00 120.44 ? 227 ASN D N   1 
ATOM   4149 C CA  . ASN B 2 227 ? 144.046 179.540 90.235  1.00 120.54 ? 227 ASN D CA  1 
ATOM   4150 C C   . ASN B 2 227 ? 144.576 178.782 91.444  1.00 120.49 ? 227 ASN D C   1 
ATOM   4151 O O   . ASN B 2 227 ? 144.437 177.557 91.523  1.00 119.11 ? 227 ASN D O   1 
ATOM   4152 C CB  . ASN B 2 227 ? 142.522 179.651 90.310  1.00 121.08 ? 227 ASN D CB  1 
ATOM   4153 C CG  . ASN B 2 227 ? 141.918 180.279 89.070  1.00 120.68 ? 227 ASN D CG  1 
ATOM   4154 O OD1 . ASN B 2 227 ? 142.614 180.540 88.090  1.00 120.83 ? 227 ASN D OD1 1 
ATOM   4155 N ND2 . ASN B 2 227 ? 140.615 180.525 89.109  1.00 119.48 ? 227 ASN D ND2 1 
ATOM   4156 N N   . VAL B 2 228 ? 145.181 179.509 92.379  1.00 116.58 ? 228 VAL D N   1 
ATOM   4157 C CA  . VAL B 2 228 ? 145.730 178.933 93.601  1.00 116.45 ? 228 VAL D CA  1 
ATOM   4158 C C   . VAL B 2 228 ? 145.102 179.638 94.794  1.00 114.96 ? 228 VAL D C   1 
ATOM   4159 O O   . VAL B 2 228 ? 145.110 180.872 94.867  1.00 114.94 ? 228 VAL D O   1 
ATOM   4160 C CB  . VAL B 2 228 ? 147.265 179.040 93.641  1.00 115.60 ? 228 VAL D CB  1 
ATOM   4161 C CG1 . VAL B 2 228 ? 147.787 178.688 95.022  1.00 115.34 ? 228 VAL D CG1 1 
ATOM   4162 C CG2 . VAL B 2 228 ? 147.877 178.119 92.601  1.00 115.38 ? 228 VAL D CG2 1 
ATOM   4163 N N   . ASN B 2 229 ? 144.554 178.854 95.719  1.00 106.00 ? 229 ASN D N   1 
ATOM   4164 C CA  . ASN B 2 229 ? 143.956 179.366 96.945  1.00 105.42 ? 229 ASN D CA  1 
ATOM   4165 C C   . ASN B 2 229 ? 144.743 178.825 98.128  1.00 105.31 ? 229 ASN D C   1 
ATOM   4166 O O   . ASN B 2 229 ? 144.896 177.608 98.269  1.00 104.02 ? 229 ASN D O   1 
ATOM   4167 C CB  . ASN B 2 229 ? 142.484 178.968 97.049  1.00 105.99 ? 229 ASN D CB  1 
ATOM   4168 N N   . HIS B 2 230 ? 145.238 179.725 98.972  1.00 101.08 ? 230 HIS D N   1 
ATOM   4169 C CA  . HIS B 2 230 ? 146.047 179.369 100.134 1.00 100.68 ? 230 HIS D CA  1 
ATOM   4170 C C   . HIS B 2 230 ? 145.545 180.090 101.377 1.00 99.51  ? 230 HIS D C   1 
ATOM   4171 O O   . HIS B 2 230 ? 146.301 180.756 102.087 1.00 98.82  ? 230 HIS D O   1 
ATOM   4172 C CB  . HIS B 2 230 ? 147.524 179.665 99.911  1.00 98.67  ? 230 HIS D CB  1 
ATOM   4173 C CG  . HIS B 2 230 ? 148.424 178.885 100.814 1.00 97.02  ? 230 HIS D CG  1 
ATOM   4174 N ND1 . HIS B 2 230 ? 149.797 178.960 100.746 1.00 95.89  ? 230 HIS D ND1 1 
ATOM   4175 C CD2 . HIS B 2 230 ? 148.145 178.007 101.805 1.00 97.77  ? 230 HIS D CD2 1 
ATOM   4176 C CE1 . HIS B 2 230 ? 150.326 178.162 101.656 1.00 97.75  ? 230 HIS D CE1 1 
ATOM   4177 N NE2 . HIS B 2 230 ? 149.344 177.571 102.312 1.00 96.83  ? 230 HIS D NE2 1 
ATOM   4178 N N   . LYS B 2 231 ? 144.243 179.983 101.632 1.00 103.94 ? 231 LYS D N   1 
ATOM   4179 C CA  . LYS B 2 231 ? 143.645 180.592 102.819 1.00 104.23 ? 231 LYS D CA  1 
ATOM   4180 C C   . LYS B 2 231 ? 144.419 180.347 104.112 1.00 103.56 ? 231 LYS D C   1 
ATOM   4181 O O   . LYS B 2 231 ? 144.476 181.272 104.940 1.00 101.78 ? 231 LYS D O   1 
ATOM   4182 C CB  . LYS B 2 231 ? 142.195 180.106 102.965 1.00 104.06 ? 231 LYS D CB  1 
ATOM   4183 N N   . PRO B 2 232 ? 145.010 179.169 104.368 1.00 100.61 ? 232 PRO D N   1 
ATOM   4184 C CA  . PRO B 2 232 ? 145.864 179.042 105.564 1.00 101.26 ? 232 PRO D CA  1 
ATOM   4185 C C   . PRO B 2 232 ? 146.987 180.066 105.626 1.00 100.42 ? 232 PRO D C   1 
ATOM   4186 O O   . PRO B 2 232 ? 147.303 180.565 106.713 1.00 97.17  ? 232 PRO D O   1 
ATOM   4187 C CB  . PRO B 2 232 ? 146.402 177.611 105.450 1.00 97.82  ? 232 PRO D CB  1 
ATOM   4188 C CG  . PRO B 2 232 ? 145.340 176.881 104.733 1.00 97.81  ? 232 PRO D CG  1 
ATOM   4189 C CD  . PRO B 2 232 ? 144.756 177.854 103.748 1.00 97.96  ? 232 PRO D CD  1 
ATOM   4190 N N   . SER B 2 233 ? 147.602 180.394 104.492 1.00 108.09 ? 233 SER D N   1 
ATOM   4191 C CA  . SER B 2 233 ? 148.601 181.452 104.430 1.00 106.69 ? 233 SER D CA  1 
ATOM   4192 C C   . SER B 2 233 ? 148.044 182.750 103.864 1.00 107.88 ? 233 SER D C   1 
ATOM   4193 O O   . SER B 2 233 ? 148.772 183.747 103.806 1.00 106.23 ? 233 SER D O   1 
ATOM   4194 C CB  . SER B 2 233 ? 149.805 180.999 103.597 1.00 105.68 ? 233 SER D CB  1 
ATOM   4195 O OG  . SER B 2 233 ? 149.658 181.372 102.239 1.00 107.49 ? 233 SER D OG  1 
ATOM   4196 N N   . ASN B 2 234 ? 146.776 182.758 103.453 1.00 110.05 ? 234 ASN D N   1 
ATOM   4197 C CA  . ASN B 2 234 ? 146.100 183.942 102.924 1.00 110.50 ? 234 ASN D CA  1 
ATOM   4198 C C   . ASN B 2 234 ? 146.869 184.535 101.743 1.00 111.56 ? 234 ASN D C   1 
ATOM   4199 O O   . ASN B 2 234 ? 147.243 185.709 101.728 1.00 112.69 ? 234 ASN D O   1 
ATOM   4200 C CB  . ASN B 2 234 ? 145.885 184.984 104.026 1.00 109.68 ? 234 ASN D CB  1 
ATOM   4201 N N   . THR B 2 235 ? 147.103 183.690 100.742 1.00 110.30 ? 235 THR D N   1 
ATOM   4202 C CA  . THR B 2 235 ? 147.803 184.093 99.533  1.00 109.70 ? 235 THR D CA  1 
ATOM   4203 C C   . THR B 2 235 ? 147.054 183.561 98.320  1.00 109.56 ? 235 THR D C   1 
ATOM   4204 O O   . THR B 2 235 ? 146.432 182.497 98.374  1.00 109.68 ? 235 THR D O   1 
ATOM   4205 C CB  . THR B 2 235 ? 149.252 183.590 99.520  1.00 109.98 ? 235 THR D CB  1 
ATOM   4206 O OG1 . THR B 2 235 ? 149.785 183.632 100.850 1.00 110.19 ? 235 THR D OG1 1 
ATOM   4207 C CG2 . THR B 2 235 ? 150.110 184.457 98.612  1.00 109.79 ? 235 THR D CG2 1 
ATOM   4208 N N   . LYS B 2 236 ? 147.116 184.317 97.223  1.00 118.45 ? 236 LYS D N   1 
ATOM   4209 C CA  . LYS B 2 236 ? 146.443 183.924 95.986  1.00 120.01 ? 236 LYS D CA  1 
ATOM   4210 C C   . LYS B 2 236 ? 147.200 184.554 94.820  1.00 119.83 ? 236 LYS D C   1 
ATOM   4211 O O   . LYS B 2 236 ? 147.048 185.750 94.553  1.00 120.26 ? 236 LYS D O   1 
ATOM   4212 C CB  . LYS B 2 236 ? 144.981 184.347 95.997  1.00 119.62 ? 236 LYS D CB  1 
ATOM   4213 N N   . VAL B 2 237 ? 148.009 183.748 94.137  1.00 121.58 ? 237 VAL D N   1 
ATOM   4214 C CA  . VAL B 2 237 ? 148.738 184.167 92.947  1.00 121.46 ? 237 VAL D CA  1 
ATOM   4215 C C   . VAL B 2 237 ? 148.291 183.288 91.788  1.00 122.03 ? 237 VAL D C   1 
ATOM   4216 O O   . VAL B 2 237 ? 148.325 182.057 91.889  1.00 121.85 ? 237 VAL D O   1 
ATOM   4217 C CB  . VAL B 2 237 ? 150.261 184.075 93.149  1.00 121.58 ? 237 VAL D CB  1 
ATOM   4218 C CG1 . VAL B 2 237 ? 150.990 184.355 91.843  1.00 121.44 ? 237 VAL D CG1 1 
ATOM   4219 C CG2 . VAL B 2 237 ? 150.710 185.039 94.235  1.00 120.25 ? 237 VAL D CG2 1 
ATOM   4220 N N   . ASP B 2 238 ? 147.867 183.918 90.695  1.00 123.95 ? 238 ASP D N   1 
ATOM   4221 C CA  . ASP B 2 238 ? 147.339 183.215 89.535  1.00 124.05 ? 238 ASP D CA  1 
ATOM   4222 C C   . ASP B 2 238 ? 148.159 183.558 88.300  1.00 124.10 ? 238 ASP D C   1 
ATOM   4223 O O   . ASP B 2 238 ? 148.537 184.716 88.097  1.00 123.81 ? 238 ASP D O   1 
ATOM   4224 C CB  . ASP B 2 238 ? 145.866 183.568 89.298  1.00 124.26 ? 238 ASP D CB  1 
ATOM   4225 C CG  . ASP B 2 238 ? 144.962 183.090 90.419  1.00 124.47 ? 238 ASP D CG  1 
ATOM   4226 O OD1 . ASP B 2 238 ? 145.442 182.351 91.304  1.00 122.97 ? 238 ASP D OD1 1 
ATOM   4227 O OD2 . ASP B 2 238 ? 143.767 183.455 90.417  1.00 125.08 ? 238 ASP D OD2 1 
ATOM   4228 N N   . LYS B 2 239 ? 148.430 182.546 87.479  1.00 122.17 ? 239 LYS D N   1 
ATOM   4229 C CA  . LYS B 2 239 ? 149.174 182.714 86.240  1.00 122.58 ? 239 LYS D CA  1 
ATOM   4230 C C   . LYS B 2 239 ? 148.444 182.011 85.103  1.00 121.39 ? 239 LYS D C   1 
ATOM   4231 O O   . LYS B 2 239 ? 147.793 180.983 85.304  1.00 121.18 ? 239 LYS D O   1 
ATOM   4232 C CB  . LYS B 2 239 ? 150.604 182.165 86.359  1.00 121.49 ? 239 LYS D CB  1 
ATOM   4233 C CG  . LYS B 2 239 ? 151.509 182.973 87.277  1.00 120.80 ? 239 LYS D CG  1 
ATOM   4234 C CD  . LYS B 2 239 ? 151.569 184.432 86.854  1.00 121.16 ? 239 LYS D CD  1 
ATOM   4235 C CE  . LYS B 2 239 ? 152.153 184.585 85.458  1.00 121.37 ? 239 LYS D CE  1 
ATOM   4236 N NZ  . LYS B 2 239 ? 152.042 185.984 84.964  1.00 121.59 ? 239 LYS D NZ  1 
ATOM   4237 N N   . LYS B 2 240 ? 148.558 182.579 83.906  1.00 127.68 ? 240 LYS D N   1 
ATOM   4238 C CA  . LYS B 2 240 ? 147.934 182.032 82.708  1.00 128.21 ? 240 LYS D CA  1 
ATOM   4239 C C   . LYS B 2 240 ? 149.011 181.518 81.764  1.00 129.21 ? 240 LYS D C   1 
ATOM   4240 O O   . LYS B 2 240 ? 149.925 182.262 81.394  1.00 129.36 ? 240 LYS D O   1 
ATOM   4241 C CB  . LYS B 2 240 ? 147.076 183.085 82.003  1.00 128.77 ? 240 LYS D CB  1 
ATOM   4242 C CG  . LYS B 2 240 ? 146.402 182.579 80.736  1.00 129.74 ? 240 LYS D CG  1 
ATOM   4243 C CD  . LYS B 2 240 ? 145.711 183.704 79.981  1.00 129.42 ? 240 LYS D CD  1 
ATOM   4244 C CE  . LYS B 2 240 ? 146.718 184.694 79.424  1.00 128.54 ? 240 LYS D CE  1 
ATOM   4245 N NZ  . LYS B 2 240 ? 147.646 184.051 78.452  1.00 127.63 ? 240 LYS D NZ  1 
ATOM   4246 N N   . VAL B 2 241 ? 148.894 180.253 81.371  1.00 131.96 ? 241 VAL D N   1 
ATOM   4247 C CA  . VAL B 2 241 ? 149.859 179.613 80.487  1.00 132.78 ? 241 VAL D CA  1 
ATOM   4248 C C   . VAL B 2 241 ? 149.366 179.721 79.050  1.00 132.56 ? 241 VAL D C   1 
ATOM   4249 O O   . VAL B 2 241 ? 148.160 179.784 78.783  1.00 131.95 ? 241 VAL D O   1 
ATOM   4250 C CB  . VAL B 2 241 ? 150.102 178.144 80.897  1.00 131.48 ? 241 VAL D CB  1 
ATOM   4251 C CG1 . VAL B 2 241 ? 148.940 177.264 80.471  1.00 130.28 ? 241 VAL D CG1 1 
ATOM   4252 C CG2 . VAL B 2 241 ? 151.412 177.634 80.318  1.00 130.88 ? 241 VAL D CG2 1 
ATOM   4253 N N   . GLU B 2 242 ? 150.317 179.759 78.112  1.00 135.30 ? 242 GLU D N   1 
ATOM   4254 C CA  . GLU B 2 242 ? 150.010 179.918 76.698  1.00 135.37 ? 242 GLU D CA  1 
ATOM   4255 C C   . GLU B 2 242 ? 151.168 179.359 75.893  1.00 135.59 ? 242 GLU D C   1 
ATOM   4256 O O   . GLU B 2 242 ? 152.327 179.627 76.240  1.00 134.98 ? 242 GLU D O   1 
ATOM   4257 C CB  . GLU B 2 242 ? 149.774 181.392 76.346  1.00 135.29 ? 242 GLU D CB  1 
ATOM   4258 C CG  . GLU B 2 242 ? 149.590 181.669 74.862  1.00 135.48 ? 242 GLU D CG  1 
ATOM   4259 C CD  . GLU B 2 242 ? 150.762 182.418 74.260  1.00 135.97 ? 242 GLU D CD  1 
ATOM   4260 O OE1 . GLU B 2 242 ? 151.655 182.841 75.024  1.00 136.07 ? 242 GLU D OE1 1 
ATOM   4261 O OE2 . GLU B 2 242 ? 150.791 182.582 73.023  1.00 135.55 ? 242 GLU D OE2 1 
ATOM   4262 N N   . PRO B 2 243 ? 150.910 178.583 74.840  1.00 138.99 ? 243 PRO D N   1 
ATOM   4263 C CA  . PRO B 2 243 ? 152.014 178.001 74.065  1.00 138.60 ? 243 PRO D CA  1 
ATOM   4264 C C   . PRO B 2 243 ? 152.893 179.073 73.437  1.00 138.64 ? 243 PRO D C   1 
ATOM   4265 O O   . PRO B 2 243 ? 152.417 180.130 73.019  1.00 137.95 ? 243 PRO D O   1 
ATOM   4266 C CB  . PRO B 2 243 ? 151.297 177.164 72.997  1.00 138.10 ? 243 PRO D CB  1 
ATOM   4267 C CG  . PRO B 2 243 ? 149.905 177.711 72.941  1.00 138.43 ? 243 PRO D CG  1 
ATOM   4268 C CD  . PRO B 2 243 ? 149.594 178.160 74.333  1.00 138.34 ? 243 PRO D CD  1 
ATOM   4269 N N   . LYS B 2 244 ? 154.189 178.784 73.374  1.00 137.76 ? 244 LYS D N   1 
ATOM   4270 C CA  . LYS B 2 244 ? 155.161 179.713 72.810  1.00 137.44 ? 244 LYS D CA  1 
ATOM   4271 C C   . LYS B 2 244 ? 155.736 179.175 71.503  1.00 137.36 ? 244 LYS D C   1 
ATOM   4272 O O   . LYS B 2 244 ? 155.817 177.964 71.300  1.00 137.10 ? 244 LYS D O   1 
ATOM   4273 C CB  . LYS B 2 244 ? 156.288 179.983 73.810  1.00 136.95 ? 244 LYS D CB  1 
ATOM   4274 C CG  . LYS B 2 244 ? 157.175 181.161 73.447  1.00 136.62 ? 244 LYS D CG  1 
ATOM   4275 C CD  . LYS B 2 244 ? 156.398 182.465 73.497  1.00 136.57 ? 244 LYS D CD  1 
ATOM   4276 C CE  . LYS B 2 244 ? 155.936 182.777 74.911  1.00 136.44 ? 244 LYS D CE  1 
ATOM   4277 N NZ  . LYS B 2 244 ? 155.090 184.002 74.962  1.00 135.91 ? 244 LYS D NZ  1 
ATOM   4278 N N   . ALA C 3 20  ? 160.715 138.809 125.072 1.00 46.36  ? 20  ALA Q N   1 
ATOM   4279 C CA  . ALA C 3 20  ? 161.345 139.259 123.837 1.00 49.83  ? 20  ALA Q CA  1 
ATOM   4280 C C   . ALA C 3 20  ? 161.690 140.741 123.914 1.00 53.33  ? 20  ALA Q C   1 
ATOM   4281 O O   . ALA C 3 20  ? 160.836 141.567 124.233 1.00 55.59  ? 20  ALA Q O   1 
ATOM   4282 C CB  . ALA C 3 20  ? 160.440 138.987 122.651 1.00 44.79  ? 20  ALA Q CB  1 
ATOM   4283 N N   . SER C 3 21  ? 162.952 141.068 123.623 1.00 58.73  ? 21  SER Q N   1 
ATOM   4284 C CA  . SER C 3 21  ? 163.389 142.460 123.676 1.00 59.91  ? 21  SER Q CA  1 
ATOM   4285 C C   . SER C 3 21  ? 162.667 143.301 122.630 1.00 60.26  ? 21  SER Q C   1 
ATOM   4286 O O   . SER C 3 21  ? 162.143 144.378 122.935 1.00 58.20  ? 21  SER Q O   1 
ATOM   4287 C CB  . SER C 3 21  ? 164.904 142.539 123.484 1.00 57.03  ? 21  SER Q CB  1 
ATOM   4288 O OG  . SER C 3 21  ? 165.361 143.877 123.576 1.00 57.05  ? 21  SER Q OG  1 
ATOM   4289 N N   . ASP C 3 22  ? 162.626 142.820 121.390 1.00 52.57  ? 22  ASP Q N   1 
ATOM   4290 C CA  . ASP C 3 22  ? 161.930 143.521 120.323 1.00 52.39  ? 22  ASP Q CA  1 
ATOM   4291 C C   . ASP C 3 22  ? 161.608 142.521 119.223 1.00 55.29  ? 22  ASP Q C   1 
ATOM   4292 O O   . ASP C 3 22  ? 162.436 141.671 118.890 1.00 54.64  ? 22  ASP Q O   1 
ATOM   4293 C CB  . ASP C 3 22  ? 162.769 144.678 119.772 1.00 54.20  ? 22  ASP Q CB  1 
ATOM   4294 C CG  . ASP C 3 22  ? 161.924 145.737 119.097 1.00 59.16  ? 22  ASP Q CG  1 
ATOM   4295 O OD1 . ASP C 3 22  ? 160.682 145.607 119.112 1.00 57.27  ? 22  ASP Q OD1 1 
ATOM   4296 O OD2 . ASP C 3 22  ? 162.500 146.702 118.553 1.00 58.89  ? 22  ASP Q OD2 1 
ATOM   4297 N N   . ILE C 3 23  ? 160.407 142.633 118.663 1.00 44.17  ? 23  ILE Q N   1 
ATOM   4298 C CA  . ILE C 3 23  ? 159.902 141.684 117.681 1.00 41.29  ? 23  ILE Q CA  1 
ATOM   4299 C C   . ILE C 3 23  ? 159.632 142.420 116.379 1.00 42.75  ? 23  ILE Q C   1 
ATOM   4300 O O   . ILE C 3 23  ? 159.015 143.490 116.377 1.00 50.22  ? 23  ILE Q O   1 
ATOM   4301 C CB  . ILE C 3 23  ? 158.630 140.977 118.188 1.00 34.21  ? 23  ILE Q CB  1 
ATOM   4302 C CG1 . ILE C 3 23  ? 158.967 140.134 119.416 1.00 39.01  ? 23  ILE Q CG1 1 
ATOM   4303 C CG2 . ILE C 3 23  ? 158.001 140.137 117.084 1.00 36.73  ? 23  ILE Q CG2 1 
ATOM   4304 C CD1 . ILE C 3 23  ? 158.000 139.024 119.671 1.00 41.07  ? 23  ILE Q CD1 1 
ATOM   4305 N N   . GLN C 3 24  ? 160.099 141.847 115.274 1.00 36.97  ? 24  GLN Q N   1 
ATOM   4306 C CA  . GLN C 3 24  ? 159.934 142.432 113.952 1.00 36.20  ? 24  GLN Q CA  1 
ATOM   4307 C C   . GLN C 3 24  ? 158.918 141.625 113.156 1.00 39.22  ? 24  GLN Q C   1 
ATOM   4308 O O   . GLN C 3 24  ? 159.031 140.400 113.056 1.00 43.53  ? 24  GLN Q O   1 
ATOM   4309 C CB  . GLN C 3 24  ? 161.272 142.481 113.212 1.00 34.74  ? 24  GLN Q CB  1 
ATOM   4310 N N   . MET C 3 25  ? 157.928 142.313 112.596 1.00 37.00  ? 25  MET Q N   1 
ATOM   4311 C CA  . MET C 3 25  ? 156.949 141.710 111.701 1.00 29.17  ? 25  MET Q CA  1 
ATOM   4312 C C   . MET C 3 25  ? 157.343 142.012 110.262 1.00 32.60  ? 25  MET Q C   1 
ATOM   4313 O O   . MET C 3 25  ? 157.387 143.179 109.859 1.00 35.41  ? 25  MET Q O   1 
ATOM   4314 C CB  . MET C 3 25  ? 155.543 142.231 111.995 1.00 32.71  ? 25  MET Q CB  1 
ATOM   4315 C CG  . MET C 3 25  ? 154.905 141.637 113.233 1.00 25.46  ? 25  MET Q CG  1 
ATOM   4316 S SD  . MET C 3 25  ? 154.067 140.099 112.808 1.00 41.80  ? 25  MET Q SD  1 
ATOM   4317 C CE  . MET C 3 25  ? 154.060 139.255 114.375 1.00 25.54  ? 25  MET Q CE  1 
ATOM   4318 N N   . THR C 3 26  ? 157.622 140.966 109.493 1.00 28.99  ? 26  THR Q N   1 
ATOM   4319 C CA  . THR C 3 26  ? 158.091 141.099 108.119 1.00 29.96  ? 26  THR Q CA  1 
ATOM   4320 C C   . THR C 3 26  ? 156.971 140.687 107.174 1.00 32.22  ? 26  THR Q C   1 
ATOM   4321 O O   . THR C 3 26  ? 156.667 139.497 107.047 1.00 32.12  ? 26  THR Q O   1 
ATOM   4322 C CB  . THR C 3 26  ? 159.336 140.249 107.887 1.00 32.31  ? 26  THR Q CB  1 
ATOM   4323 O OG1 . THR C 3 26  ? 160.298 140.529 108.910 1.00 36.90  ? 26  THR Q OG1 1 
ATOM   4324 C CG2 . THR C 3 26  ? 159.941 140.561 106.532 1.00 33.67  ? 26  THR Q CG2 1 
ATOM   4325 N N   . GLN C 3 27  ? 156.364 141.667 106.513 1.00 21.26  ? 27  GLN Q N   1 
ATOM   4326 C CA  . GLN C 3 27  ? 155.335 141.386 105.524 1.00 30.35  ? 27  GLN Q CA  1 
ATOM   4327 C C   . GLN C 3 27  ? 155.990 141.056 104.190 1.00 37.33  ? 27  GLN Q C   1 
ATOM   4328 O O   . GLN C 3 27  ? 156.836 141.812 103.702 1.00 37.66  ? 27  GLN Q O   1 
ATOM   4329 C CB  . GLN C 3 27  ? 154.389 142.576 105.381 1.00 26.79  ? 27  GLN Q CB  1 
ATOM   4330 C CG  . GLN C 3 27  ? 153.606 142.895 106.638 1.00 21.21  ? 27  GLN Q CG  1 
ATOM   4331 C CD  . GLN C 3 27  ? 152.194 143.340 106.342 1.00 18.58  ? 27  GLN Q CD  1 
ATOM   4332 O OE1 . GLN C 3 27  ? 151.628 144.166 107.053 1.00 21.55  ? 27  GLN Q OE1 1 
ATOM   4333 N NE2 . GLN C 3 27  ? 151.613 142.791 105.287 1.00 24.06  ? 27  GLN Q NE2 1 
ATOM   4334 N N   . SER C 3 28  ? 155.606 139.917 103.605 1.00 37.53  ? 28  SER Q N   1 
ATOM   4335 C CA  . SER C 3 28  ? 156.302 139.454 102.405 1.00 32.58  ? 28  SER Q CA  1 
ATOM   4336 C C   . SER C 3 28  ? 155.949 140.278 101.175 1.00 44.07  ? 28  SER Q C   1 
ATOM   4337 O O   . SER C 3 28  ? 156.872 140.810 100.533 1.00 53.15  ? 28  SER Q O   1 
ATOM   4338 C CB  . SER C 3 28  ? 156.045 137.960 102.195 1.00 35.51  ? 28  SER Q CB  1 
ATOM   4339 O OG  . SER C 3 28  ? 156.328 137.233 103.377 1.00 45.37  ? 28  SER Q OG  1 
ATOM   4340 N N   . PRO C 3 29  ? 154.675 140.434 100.778 1.00 43.80  ? 29  PRO Q N   1 
ATOM   4341 C CA  . PRO C 3 29  ? 154.380 141.288 99.621  1.00 37.45  ? 29  PRO Q CA  1 
ATOM   4342 C C   . PRO C 3 29  ? 154.366 142.752 100.030 1.00 44.04  ? 29  PRO Q C   1 
ATOM   4343 O O   . PRO C 3 29  ? 153.461 143.207 100.737 1.00 46.11  ? 29  PRO Q O   1 
ATOM   4344 C CB  . PRO C 3 29  ? 152.992 140.802 99.172  1.00 30.85  ? 29  PRO Q CB  1 
ATOM   4345 C CG  . PRO C 3 29  ? 152.586 139.709 100.142 1.00 38.10  ? 29  PRO Q CG  1 
ATOM   4346 C CD  . PRO C 3 29  ? 153.434 139.888 101.349 1.00 39.92  ? 29  PRO Q CD  1 
ATOM   4347 N N   . SER C 3 30  ? 155.383 143.496 99.596  1.00 38.75  ? 30  SER Q N   1 
ATOM   4348 C CA  . SER C 3 30  ? 155.382 144.935 99.835  1.00 36.14  ? 30  SER Q CA  1 
ATOM   4349 C C   . SER C 3 30  ? 154.396 145.637 98.912  1.00 37.91  ? 30  SER Q C   1 
ATOM   4350 O O   . SER C 3 30  ? 153.716 146.584 99.321  1.00 41.68  ? 30  SER Q O   1 
ATOM   4351 C CB  . SER C 3 30  ? 156.790 145.499 99.658  1.00 44.15  ? 30  SER Q CB  1 
ATOM   4352 O OG  . SER C 3 30  ? 156.877 146.818 100.164 1.00 44.40  ? 30  SER Q OG  1 
ATOM   4353 N N   . SER C 3 31  ? 154.309 145.186 97.664  1.00 40.92  ? 31  SER Q N   1 
ATOM   4354 C CA  . SER C 3 31  ? 153.346 145.688 96.698  1.00 37.48  ? 31  SER Q CA  1 
ATOM   4355 C C   . SER C 3 31  ? 152.640 144.505 96.056  1.00 41.18  ? 31  SER Q C   1 
ATOM   4356 O O   . SER C 3 31  ? 153.273 143.494 95.739  1.00 44.41  ? 31  SER Q O   1 
ATOM   4357 C CB  . SER C 3 31  ? 154.023 146.546 95.624  1.00 44.37  ? 31  SER Q CB  1 
ATOM   4358 O OG  . SER C 3 31  ? 154.877 147.516 96.208  1.00 48.19  ? 31  SER Q OG  1 
ATOM   4359 N N   . LEU C 3 32  ? 151.330 144.631 95.869  1.00 42.78  ? 32  LEU Q N   1 
ATOM   4360 C CA  . LEU C 3 32  ? 150.521 143.536 95.346  1.00 40.79  ? 32  LEU Q CA  1 
ATOM   4361 C C   . LEU C 3 32  ? 149.529 144.090 94.338  1.00 42.79  ? 32  LEU Q C   1 
ATOM   4362 O O   . LEU C 3 32  ? 148.741 144.980 94.667  1.00 46.55  ? 32  LEU Q O   1 
ATOM   4363 C CB  . LEU C 3 32  ? 149.792 142.809 96.478  1.00 41.66  ? 32  LEU Q CB  1 
ATOM   4364 C CG  . LEU C 3 32  ? 148.900 141.626 96.111  1.00 38.91  ? 32  LEU Q CG  1 
ATOM   4365 C CD1 . LEU C 3 32  ? 149.626 140.678 95.179  1.00 46.76  ? 32  LEU Q CD1 1 
ATOM   4366 C CD2 . LEU C 3 32  ? 148.460 140.904 97.369  1.00 39.95  ? 32  LEU Q CD2 1 
ATOM   4367 N N   . SER C 3 33  ? 149.565 143.563 93.119  1.00 47.93  ? 33  SER Q N   1 
ATOM   4368 C CA  . SER C 3 33  ? 148.636 143.942 92.064  1.00 46.91  ? 33  SER Q CA  1 
ATOM   4369 C C   . SER C 3 33  ? 147.668 142.795 91.824  1.00 50.75  ? 33  SER Q C   1 
ATOM   4370 O O   . SER C 3 33  ? 148.090 141.645 91.664  1.00 46.69  ? 33  SER Q O   1 
ATOM   4371 C CB  . SER C 3 33  ? 149.380 144.289 90.774  1.00 48.09  ? 33  SER Q CB  1 
ATOM   4372 O OG  . SER C 3 33  ? 150.387 145.255 91.010  1.00 54.76  ? 33  SER Q OG  1 
ATOM   4373 N N   . ALA C 3 34  ? 146.375 143.107 91.798  1.00 54.85  ? 34  ALA Q N   1 
ATOM   4374 C CA  . ALA C 3 34  ? 145.341 142.099 91.634  1.00 53.45  ? 34  ALA Q CA  1 
ATOM   4375 C C   . ALA C 3 34  ? 144.223 142.667 90.773  1.00 55.82  ? 34  ALA Q C   1 
ATOM   4376 O O   . ALA C 3 34  ? 144.297 143.799 90.288  1.00 58.11  ? 34  ALA Q O   1 
ATOM   4377 C CB  . ALA C 3 34  ? 144.803 141.632 92.989  1.00 54.79  ? 34  ALA Q CB  1 
ATOM   4378 N N   . SER C 3 35  ? 143.178 141.866 90.586  1.00 60.15  ? 35  SER Q N   1 
ATOM   4379 C CA  . SER C 3 35  ? 142.024 142.256 89.794  1.00 61.93  ? 35  SER Q CA  1 
ATOM   4380 C C   . SER C 3 35  ? 140.756 141.877 90.542  1.00 60.43  ? 35  SER Q C   1 
ATOM   4381 O O   . SER C 3 35  ? 140.769 141.027 91.435  1.00 64.45  ? 35  SER Q O   1 
ATOM   4382 C CB  . SER C 3 35  ? 142.040 141.597 88.409  1.00 59.43  ? 35  SER Q CB  1 
ATOM   4383 O OG  . SER C 3 35  ? 141.267 142.341 87.483  1.00 61.50  ? 35  SER Q OG  1 
ATOM   4384 N N   . VAL C 3 36  ? 139.652 142.526 90.167  1.00 56.13  ? 36  VAL Q N   1 
ATOM   4385 C CA  . VAL C 3 36  ? 138.389 142.303 90.856  1.00 55.78  ? 36  VAL Q CA  1 
ATOM   4386 C C   . VAL C 3 36  ? 137.965 140.852 90.691  1.00 60.35  ? 36  VAL Q C   1 
ATOM   4387 O O   . VAL C 3 36  ? 137.923 140.320 89.575  1.00 63.45  ? 36  VAL Q O   1 
ATOM   4388 C CB  . VAL C 3 36  ? 137.316 143.263 90.326  1.00 58.05  ? 36  VAL Q CB  1 
ATOM   4389 C CG1 . VAL C 3 36  ? 135.999 143.031 91.046  1.00 57.46  ? 36  VAL Q CG1 1 
ATOM   4390 C CG2 . VAL C 3 36  ? 137.773 144.701 90.484  1.00 60.93  ? 36  VAL Q CG2 1 
ATOM   4391 N N   . GLY C 3 37  ? 137.641 140.205 91.809  1.00 55.81  ? 37  GLY Q N   1 
ATOM   4392 C CA  . GLY C 3 37  ? 137.263 138.811 91.811  1.00 54.57  ? 37  GLY Q CA  1 
ATOM   4393 C C   . GLY C 3 37  ? 138.406 137.838 91.992  1.00 56.37  ? 37  GLY Q C   1 
ATOM   4394 O O   . GLY C 3 37  ? 138.159 136.631 92.095  1.00 60.50  ? 37  GLY Q O   1 
ATOM   4395 N N   . ASP C 3 38  ? 139.645 138.318 92.034  1.00 52.20  ? 38  ASP Q N   1 
ATOM   4396 C CA  . ASP C 3 38  ? 140.793 137.448 92.216  1.00 53.30  ? 38  ASP Q CA  1 
ATOM   4397 C C   . ASP C 3 38  ? 140.959 137.089 93.692  1.00 55.55  ? 38  ASP Q C   1 
ATOM   4398 O O   . ASP C 3 38  ? 140.354 137.694 94.582  1.00 56.85  ? 38  ASP Q O   1 
ATOM   4399 C CB  . ASP C 3 38  ? 142.057 138.119 91.678  1.00 55.88  ? 38  ASP Q CB  1 
ATOM   4400 C CG  . ASP C 3 38  ? 143.193 137.140 91.455  1.00 60.09  ? 38  ASP Q CG  1 
ATOM   4401 O OD1 . ASP C 3 38  ? 143.081 135.980 91.902  1.00 58.84  ? 38  ASP Q OD1 1 
ATOM   4402 O OD2 . ASP C 3 38  ? 144.197 137.531 90.825  1.00 61.44  ? 38  ASP Q OD2 1 
ATOM   4403 N N   . ARG C 3 39  ? 141.787 136.081 93.946  1.00 49.02  ? 39  ARG Q N   1 
ATOM   4404 C CA  . ARG C 3 39  ? 142.104 135.632 95.295  1.00 49.05  ? 39  ARG Q CA  1 
ATOM   4405 C C   . ARG C 3 39  ? 143.557 135.972 95.595  1.00 51.21  ? 39  ARG Q C   1 
ATOM   4406 O O   . ARG C 3 39  ? 144.459 135.550 94.864  1.00 51.80  ? 39  ARG Q O   1 
ATOM   4407 C CB  . ARG C 3 39  ? 141.864 134.131 95.443  1.00 47.80  ? 39  ARG Q CB  1 
ATOM   4408 C CG  . ARG C 3 39  ? 141.945 133.630 96.869  1.00 48.53  ? 39  ARG Q CG  1 
ATOM   4409 C CD  . ARG C 3 39  ? 141.896 132.115 96.921  1.00 51.70  ? 39  ARG Q CD  1 
ATOM   4410 N NE  . ARG C 3 39  ? 142.685 131.579 98.024  1.00 49.96  ? 39  ARG Q NE  1 
ATOM   4411 C CZ  . ARG C 3 39  ? 144.008 131.500 98.033  1.00 52.01  ? 39  ARG Q CZ  1 
ATOM   4412 N NH1 . ARG C 3 39  ? 144.732 131.918 97.008  1.00 52.09  ? 39  ARG Q NH1 1 
ATOM   4413 N NH2 . ARG C 3 39  ? 144.620 130.986 99.095  1.00 50.16  ? 39  ARG Q NH2 1 
ATOM   4414 N N   . VAL C 3 40  ? 143.781 136.731 96.666  1.00 48.77  ? 40  VAL Q N   1 
ATOM   4415 C CA  . VAL C 3 40  ? 145.119 137.148 97.061  1.00 43.14  ? 40  VAL Q CA  1 
ATOM   4416 C C   . VAL C 3 40  ? 145.349 136.783 98.519  1.00 41.02  ? 40  VAL Q C   1 
ATOM   4417 O O   . VAL C 3 40  ? 144.410 136.701 99.318  1.00 42.13  ? 40  VAL Q O   1 
ATOM   4418 C CB  . VAL C 3 40  ? 145.346 138.660 96.837  1.00 39.47  ? 40  VAL Q CB  1 
ATOM   4419 C CG1 . VAL C 3 40  ? 144.808 139.077 95.489  1.00 44.20  ? 40  VAL Q CG1 1 
ATOM   4420 C CG2 . VAL C 3 40  ? 144.691 139.472 97.940  1.00 35.84  ? 40  VAL Q CG2 1 
ATOM   4421 N N   . THR C 3 41  ? 146.614 136.547 98.858  1.00 33.88  ? 41  THR Q N   1 
ATOM   4422 C CA  . THR C 3 41  ? 147.025 136.232 100.217 1.00 34.86  ? 41  THR Q CA  1 
ATOM   4423 C C   . THR C 3 41  ? 148.160 137.156 100.626 1.00 33.24  ? 41  THR Q C   1 
ATOM   4424 O O   . THR C 3 41  ? 149.077 137.412 99.842  1.00 33.40  ? 41  THR Q O   1 
ATOM   4425 C CB  . THR C 3 41  ? 147.482 134.773 100.358 1.00 40.00  ? 41  THR Q CB  1 
ATOM   4426 O OG1 . THR C 3 41  ? 148.751 134.604 99.715  1.00 44.66  ? 41  THR Q OG1 1 
ATOM   4427 C CG2 . THR C 3 41  ? 146.471 133.825 99.736  1.00 36.39  ? 41  THR Q CG2 1 
ATOM   4428 N N   . ILE C 3 42  ? 148.091 137.653 101.857 1.00 27.91  ? 42  ILE Q N   1 
ATOM   4429 C CA  . ILE C 3 42  ? 149.122 138.504 102.436 1.00 21.42  ? 42  ILE Q CA  1 
ATOM   4430 C C   . ILE C 3 42  ? 149.656 137.796 103.671 1.00 24.62  ? 42  ILE Q C   1 
ATOM   4431 O O   . ILE C 3 42  ? 148.886 137.460 104.578 1.00 35.14  ? 42  ILE Q O   1 
ATOM   4432 C CB  . ILE C 3 42  ? 148.577 139.896 102.792 1.00 23.38  ? 42  ILE Q CB  1 
ATOM   4433 C CG1 . ILE C 3 42  ? 147.937 140.546 101.566 1.00 22.84  ? 42  ILE Q CG1 1 
ATOM   4434 C CG2 . ILE C 3 42  ? 149.680 140.774 103.347 1.00 30.39  ? 42  ILE Q CG2 1 
ATOM   4435 C CD1 . ILE C 3 42  ? 147.020 141.688 101.899 1.00 21.95  ? 42  ILE Q CD1 1 
ATOM   4436 N N   . THR C 3 43  ? 150.964 137.572 103.712 1.00 23.00  ? 43  THR Q N   1 
ATOM   4437 C CA  . THR C 3 43  ? 151.578 136.815 104.789 1.00 21.18  ? 43  THR Q CA  1 
ATOM   4438 C C   . THR C 3 43  ? 152.619 137.658 105.512 1.00 28.52  ? 43  THR Q C   1 
ATOM   4439 O O   . THR C 3 43  ? 153.176 138.607 104.953 1.00 37.49  ? 43  THR Q O   1 
ATOM   4440 C CB  . THR C 3 43  ? 152.225 135.520 104.272 1.00 36.83  ? 43  THR Q CB  1 
ATOM   4441 O OG1 . THR C 3 43  ? 152.619 134.702 105.380 1.00 35.00  ? 43  THR Q OG1 1 
ATOM   4442 C CG2 . THR C 3 43  ? 153.440 135.824 103.421 1.00 30.70  ? 43  THR Q CG2 1 
ATOM   4443 N N   . CYS C 3 44  ? 152.862 137.308 106.773 1.00 32.43  ? 44  CYS Q N   1 
ATOM   4444 C CA  . CYS C 3 44  ? 153.865 137.967 107.593 1.00 29.70  ? 44  CYS Q CA  1 
ATOM   4445 C C   . CYS C 3 44  ? 154.538 136.937 108.485 1.00 32.79  ? 44  CYS Q C   1 
ATOM   4446 O O   . CYS C 3 44  ? 153.919 135.956 108.899 1.00 35.64  ? 44  CYS Q O   1 
ATOM   4447 C CB  . CYS C 3 44  ? 153.255 139.075 108.449 1.00 25.96  ? 44  CYS Q CB  1 
ATOM   4448 S SG  . CYS C 3 44  ? 152.067 138.492 109.669 1.00 69.69  ? 44  CYS Q SG  1 
ATOM   4449 N N   . ARG C 3 45  ? 155.811 137.174 108.782 1.00 32.93  ? 45  ARG Q N   1 
ATOM   4450 C CA  . ARG C 3 45  ? 156.621 136.275 109.591 1.00 27.39  ? 45  ARG Q CA  1 
ATOM   4451 C C   . ARG C 3 45  ? 157.112 137.010 110.828 1.00 32.09  ? 45  ARG Q C   1 
ATOM   4452 O O   . ARG C 3 45  ? 157.720 138.079 110.719 1.00 41.56  ? 45  ARG Q O   1 
ATOM   4453 C CB  . ARG C 3 45  ? 157.808 135.736 108.787 1.00 32.69  ? 45  ARG Q CB  1 
ATOM   4454 C CG  . ARG C 3 45  ? 159.031 135.401 109.628 1.00 33.68  ? 45  ARG Q CG  1 
ATOM   4455 C CD  . ARG C 3 45  ? 159.785 134.195 109.099 1.00 36.21  ? 45  ARG Q CD  1 
ATOM   4456 N NE  . ARG C 3 45  ? 159.058 132.947 109.297 1.00 34.90  ? 45  ARG Q NE  1 
ATOM   4457 C CZ  . ARG C 3 45  ? 158.362 132.327 108.355 1.00 40.59  ? 45  ARG Q CZ  1 
ATOM   4458 N NH1 . ARG C 3 45  ? 158.265 132.819 107.131 1.00 33.66  ? 45  ARG Q NH1 1 
ATOM   4459 N NH2 . ARG C 3 45  ? 157.752 131.183 108.647 1.00 40.61  ? 45  ARG Q NH2 1 
ATOM   4460 N N   . ALA C 3 46  ? 156.856 136.432 111.996 1.00 30.66  ? 46  ALA Q N   1 
ATOM   4461 C CA  . ALA C 3 46  ? 157.290 137.034 113.245 1.00 26.18  ? 46  ALA Q CA  1 
ATOM   4462 C C   . ALA C 3 46  ? 158.748 136.690 113.529 1.00 32.44  ? 46  ALA Q C   1 
ATOM   4463 O O   . ALA C 3 46  ? 159.272 135.666 113.085 1.00 38.31  ? 46  ALA Q O   1 
ATOM   4464 C CB  . ALA C 3 46  ? 156.406 136.569 114.399 1.00 26.33  ? 46  ALA Q CB  1 
ATOM   4465 N N   . SER C 3 47  ? 159.407 137.574 114.280 1.00 39.13  ? 47  SER Q N   1 
ATOM   4466 C CA  . SER C 3 47  ? 160.797 137.336 114.655 1.00 35.43  ? 47  SER Q CA  1 
ATOM   4467 C C   . SER C 3 47  ? 160.922 136.111 115.551 1.00 41.60  ? 47  SER Q C   1 
ATOM   4468 O O   . SER C 3 47  ? 161.861 135.320 115.407 1.00 44.60  ? 47  SER Q O   1 
ATOM   4469 C CB  . SER C 3 47  ? 161.372 138.568 115.348 1.00 37.08  ? 47  SER Q CB  1 
ATOM   4470 O OG  . SER C 3 47  ? 162.681 138.316 115.824 1.00 47.79  ? 47  SER Q OG  1 
ATOM   4471 N N   . GLN C 3 48  ? 159.993 135.945 116.486 1.00 40.40  ? 48  GLN Q N   1 
ATOM   4472 C CA  . GLN C 3 48  ? 159.940 134.766 117.338 1.00 38.95  ? 48  GLN Q CA  1 
ATOM   4473 C C   . GLN C 3 48  ? 158.473 134.422 117.562 1.00 35.98  ? 48  GLN Q C   1 
ATOM   4474 O O   . GLN C 3 48  ? 157.579 134.987 116.928 1.00 42.10  ? 48  GLN Q O   1 
ATOM   4475 C CB  . GLN C 3 48  ? 160.689 135.004 118.654 1.00 38.39  ? 48  GLN Q CB  1 
ATOM   4476 C CG  . GLN C 3 48  ? 160.507 136.397 119.223 1.00 40.06  ? 48  GLN Q CG  1 
ATOM   4477 C CD  . GLN C 3 48  ? 161.691 136.845 120.046 1.00 42.83  ? 48  GLN Q CD  1 
ATOM   4478 O OE1 . GLN C 3 48  ? 161.866 136.417 121.185 1.00 47.50  ? 48  GLN Q OE1 1 
ATOM   4479 N NE2 . GLN C 3 48  ? 162.513 137.716 119.474 1.00 41.18  ? 48  GLN Q NE2 1 
ATOM   4480 N N   . SER C 3 49  ? 158.216 133.497 118.479 1.00 29.02  ? 49  SER Q N   1 
ATOM   4481 C CA  . SER C 3 49  ? 156.856 133.022 118.703 1.00 30.59  ? 49  SER Q CA  1 
ATOM   4482 C C   . SER C 3 49  ? 156.058 134.084 119.448 1.00 30.01  ? 49  SER Q C   1 
ATOM   4483 O O   . SER C 3 49  ? 156.321 134.362 120.621 1.00 28.10  ? 49  SER Q O   1 
ATOM   4484 C CB  . SER C 3 49  ? 156.877 131.710 119.480 1.00 32.91  ? 49  SER Q CB  1 
ATOM   4485 O OG  . SER C 3 49  ? 155.571 131.184 119.623 1.00 38.52  ? 49  SER Q OG  1 
ATOM   4486 N N   . VAL C 3 50  ? 155.086 134.684 118.763 1.00 31.44  ? 50  VAL Q N   1 
ATOM   4487 C CA  . VAL C 3 50  ? 154.119 135.570 119.395 1.00 19.58  ? 50  VAL Q CA  1 
ATOM   4488 C C   . VAL C 3 50  ? 152.831 134.834 119.737 1.00 23.14  ? 50  VAL Q C   1 
ATOM   4489 O O   . VAL C 3 50  ? 151.815 135.473 120.024 1.00 33.28  ? 50  VAL Q O   1 
ATOM   4490 C CB  . VAL C 3 50  ? 153.823 136.797 118.518 1.00 16.38  ? 50  VAL Q CB  1 
ATOM   4491 C CG1 . VAL C 3 50  ? 155.099 137.543 118.204 1.00 25.98  ? 50  VAL Q CG1 1 
ATOM   4492 C CG2 . VAL C 3 50  ? 153.127 136.383 117.238 1.00 12.93  ? 50  VAL Q CG2 1 
ATOM   4493 N N   . SER C 3 51  ? 152.854 133.506 119.717 1.00 12.54  ? 51  SER Q N   1 
ATOM   4494 C CA  . SER C 3 51  ? 151.667 132.658 119.906 1.00 15.95  ? 51  SER Q CA  1 
ATOM   4495 C C   . SER C 3 51  ? 150.667 133.043 118.813 1.00 10.37  ? 51  SER Q C   1 
ATOM   4496 O O   . SER C 3 51  ? 151.073 133.297 117.670 1.00 17.94  ? 51  SER Q O   1 
ATOM   4497 C CB  . SER C 3 51  ? 151.153 132.779 121.322 1.00 13.44  ? 51  SER Q CB  1 
ATOM   4498 O OG  . SER C 3 51  ? 152.206 132.640 122.258 1.00 18.65  ? 51  SER Q OG  1 
ATOM   4499 N N   . SER C 3 52  ? 149.374 133.100 119.116 1.00 9.48   ? 52  SER Q N   1 
ATOM   4500 C CA  . SER C 3 52  ? 148.365 133.510 118.152 1.00 12.64  ? 52  SER Q CA  1 
ATOM   4501 C C   . SER C 3 52  ? 147.938 134.958 118.346 1.00 17.97  ? 52  SER Q C   1 
ATOM   4502 O O   . SER C 3 52  ? 146.891 135.363 117.834 1.00 11.85  ? 52  SER Q O   1 
ATOM   4503 C CB  . SER C 3 52  ? 147.153 132.584 118.232 1.00 14.67  ? 52  SER Q CB  1 
ATOM   4504 O OG  . SER C 3 52  ? 147.489 131.277 117.809 1.00 23.76  ? 52  SER Q OG  1 
ATOM   4505 N N   . ALA C 3 53  ? 148.724 135.744 119.082 1.00 10.92  ? 53  ALA Q N   1 
ATOM   4506 C CA  . ALA C 3 53  ? 148.388 137.135 119.380 1.00 0.00   ? 53  ALA Q CA  1 
ATOM   4507 C C   . ALA C 3 53  ? 148.769 137.997 118.182 1.00 2.36   ? 53  ALA Q C   1 
ATOM   4508 O O   . ALA C 3 53  ? 149.782 138.701 118.173 1.00 15.07  ? 53  ALA Q O   1 
ATOM   4509 C CB  . ALA C 3 53  ? 149.092 137.592 120.649 1.00 0.00   ? 53  ALA Q CB  1 
ATOM   4510 N N   . VAL C 3 54  ? 147.934 137.934 117.147 1.00 9.39   ? 54  VAL Q N   1 
ATOM   4511 C CA  . VAL C 3 54  ? 148.162 138.663 115.905 1.00 4.09   ? 54  VAL Q CA  1 
ATOM   4512 C C   . VAL C 3 54  ? 146.837 139.227 115.410 1.00 6.72   ? 54  VAL Q C   1 
ATOM   4513 O O   . VAL C 3 54  ? 145.820 138.527 115.410 1.00 23.22  ? 54  VAL Q O   1 
ATOM   4514 C CB  . VAL C 3 54  ? 148.814 137.766 114.834 1.00 5.43   ? 54  VAL Q CB  1 
ATOM   4515 C CG1 . VAL C 3 54  ? 148.554 138.305 113.445 1.00 10.83  ? 54  VAL Q CG1 1 
ATOM   4516 C CG2 . VAL C 3 54  ? 150.306 137.669 115.079 1.00 14.10  ? 54  VAL Q CG2 1 
ATOM   4517 N N   . ALA C 3 55  ? 146.848 140.491 114.989 1.00 9.37   ? 55  ALA Q N   1 
ATOM   4518 C CA  . ALA C 3 55  ? 145.680 141.147 114.424 1.00 0.51   ? 55  ALA Q CA  1 
ATOM   4519 C C   . ALA C 3 55  ? 146.026 141.728 113.060 1.00 6.29   ? 55  ALA Q C   1 
ATOM   4520 O O   . ALA C 3 55  ? 147.189 141.996 112.752 1.00 14.28  ? 55  ALA Q O   1 
ATOM   4521 C CB  . ALA C 3 55  ? 145.148 142.249 115.345 1.00 1.66   ? 55  ALA Q CB  1 
ATOM   4522 N N   . TRP C 3 56  ? 144.996 141.910 112.236 1.00 12.48  ? 56  TRP Q N   1 
ATOM   4523 C CA  . TRP C 3 56  ? 145.136 142.449 110.891 1.00 11.06  ? 56  TRP Q CA  1 
ATOM   4524 C C   . TRP C 3 56  ? 144.271 143.692 110.741 1.00 8.23   ? 56  TRP Q C   1 
ATOM   4525 O O   . TRP C 3 56  ? 143.118 143.713 111.180 1.00 1.86   ? 56  TRP Q O   1 
ATOM   4526 C CB  . TRP C 3 56  ? 144.748 141.409 109.832 1.00 6.96   ? 56  TRP Q CB  1 
ATOM   4527 C CG  . TRP C 3 56  ? 145.813 140.383 109.593 1.00 7.21   ? 56  TRP Q CG  1 
ATOM   4528 C CD1 . TRP C 3 56  ? 145.948 139.185 110.223 1.00 0.00   ? 56  TRP Q CD1 1 
ATOM   4529 C CD2 . TRP C 3 56  ? 146.900 140.472 108.666 1.00 17.76  ? 56  TRP Q CD2 1 
ATOM   4530 N NE1 . TRP C 3 56  ? 147.047 138.519 109.746 1.00 12.84  ? 56  TRP Q NE1 1 
ATOM   4531 C CE2 . TRP C 3 56  ? 147.650 139.289 108.788 1.00 21.30  ? 56  TRP Q CE2 1 
ATOM   4532 C CE3 . TRP C 3 56  ? 147.309 141.436 107.742 1.00 5.06   ? 56  TRP Q CE3 1 
ATOM   4533 C CZ2 . TRP C 3 56  ? 148.786 139.044 108.023 1.00 2.54   ? 56  TRP Q CZ2 1 
ATOM   4534 C CZ3 . TRP C 3 56  ? 148.431 141.189 106.984 1.00 2.51   ? 56  TRP Q CZ3 1 
ATOM   4535 C CH2 . TRP C 3 56  ? 149.157 140.004 107.128 1.00 3.19   ? 56  TRP Q CH2 1 
ATOM   4536 N N   . TYR C 3 57  ? 144.832 144.724 110.113 1.00 14.58  ? 57  TYR Q N   1 
ATOM   4537 C CA  . TYR C 3 57  ? 144.160 146.005 109.954 1.00 5.39   ? 57  TYR Q CA  1 
ATOM   4538 C C   . TYR C 3 57  ? 144.144 146.412 108.490 1.00 1.79   ? 57  TYR Q C   1 
ATOM   4539 O O   . TYR C 3 57  ? 145.056 146.088 107.729 1.00 20.14  ? 57  TYR Q O   1 
ATOM   4540 C CB  . TYR C 3 57  ? 144.839 147.108 110.775 1.00 6.10   ? 57  TYR Q CB  1 
ATOM   4541 C CG  . TYR C 3 57  ? 144.876 146.840 112.257 1.00 6.86   ? 57  TYR Q CG  1 
ATOM   4542 C CD1 . TYR C 3 57  ? 145.890 146.086 112.817 1.00 1.05   ? 57  TYR Q CD1 1 
ATOM   4543 C CD2 . TYR C 3 57  ? 143.898 147.344 113.096 1.00 3.13   ? 57  TYR Q CD2 1 
ATOM   4544 C CE1 . TYR C 3 57  ? 145.928 145.841 114.162 1.00 0.00   ? 57  TYR Q CE1 1 
ATOM   4545 C CE2 . TYR C 3 57  ? 143.931 147.100 114.445 1.00 2.37   ? 57  TYR Q CE2 1 
ATOM   4546 C CZ  . TYR C 3 57  ? 144.948 146.349 114.972 1.00 0.00   ? 57  TYR Q CZ  1 
ATOM   4547 O OH  . TYR C 3 57  ? 144.987 146.102 116.320 1.00 1.43   ? 57  TYR Q OH  1 
ATOM   4548 N N   . GLN C 3 58  ? 143.095 147.132 108.106 1.00 0.00   ? 58  GLN Q N   1 
ATOM   4549 C CA  . GLN C 3 58  ? 142.947 147.671 106.761 1.00 8.77   ? 58  GLN Q CA  1 
ATOM   4550 C C   . GLN C 3 58  ? 142.865 149.187 106.843 1.00 11.19  ? 58  GLN Q C   1 
ATOM   4551 O O   . GLN C 3 58  ? 142.110 149.725 107.657 1.00 28.16  ? 58  GLN Q O   1 
ATOM   4552 C CB  . GLN C 3 58  ? 141.698 147.115 106.079 1.00 17.33  ? 58  GLN Q CB  1 
ATOM   4553 C CG  . GLN C 3 58  ? 141.447 147.684 104.702 1.00 15.55  ? 58  GLN Q CG  1 
ATOM   4554 C CD  . GLN C 3 58  ? 140.061 147.376 104.187 1.00 21.68  ? 58  GLN Q CD  1 
ATOM   4555 O OE1 . GLN C 3 58  ? 139.079 147.482 104.916 1.00 22.20  ? 58  GLN Q OE1 1 
ATOM   4556 N NE2 . GLN C 3 58  ? 139.975 146.981 102.924 1.00 21.58  ? 58  GLN Q NE2 1 
ATOM   4557 N N   . GLN C 3 59  ? 143.631 149.872 105.998 1.00 19.40  ? 59  GLN Q N   1 
ATOM   4558 C CA  . GLN C 3 59  ? 143.686 151.331 106.007 1.00 19.42  ? 59  GLN Q CA  1 
ATOM   4559 C C   . GLN C 3 59  ? 143.486 151.857 104.594 1.00 21.91  ? 59  GLN Q C   1 
ATOM   4560 O O   . GLN C 3 59  ? 144.317 151.616 103.713 1.00 14.21  ? 59  GLN Q O   1 
ATOM   4561 C CB  . GLN C 3 59  ? 145.011 151.827 106.582 1.00 15.37  ? 59  GLN Q CB  1 
ATOM   4562 C CG  . GLN C 3 59  ? 145.308 153.271 106.252 1.00 15.74  ? 59  GLN Q CG  1 
ATOM   4563 C CD  . GLN C 3 59  ? 146.095 153.963 107.331 1.00 11.20  ? 59  GLN Q CD  1 
ATOM   4564 O OE1 . GLN C 3 59  ? 147.234 153.601 107.610 1.00 16.78  ? 59  GLN Q OE1 1 
ATOM   4565 N NE2 . GLN C 3 59  ? 145.495 154.969 107.945 1.00 14.08  ? 59  GLN Q NE2 1 
ATOM   4566 N N   . LYS C 3 60  ? 142.392 152.575 104.381 1.00 29.27  ? 60  LYS Q N   1 
ATOM   4567 C CA  . LYS C 3 60  ? 142.170 153.286 103.136 1.00 27.98  ? 60  LYS Q CA  1 
ATOM   4568 C C   . LYS C 3 60  ? 143.015 154.555 103.105 1.00 33.52  ? 60  LYS Q C   1 
ATOM   4569 O O   . LYS C 3 60  ? 143.415 155.069 104.152 1.00 38.96  ? 60  LYS Q O   1 
ATOM   4570 C CB  . LYS C 3 60  ? 140.694 153.631 102.989 1.00 31.69  ? 60  LYS Q CB  1 
ATOM   4571 C CG  . LYS C 3 60  ? 139.789 152.422 102.904 1.00 30.71  ? 60  LYS Q CG  1 
ATOM   4572 C CD  . LYS C 3 60  ? 140.131 151.569 101.705 1.00 28.60  ? 60  LYS Q CD  1 
ATOM   4573 C CE  . LYS C 3 60  ? 139.108 150.473 101.510 1.00 32.62  ? 60  LYS Q CE  1 
ATOM   4574 N NZ  . LYS C 3 60  ? 137.754 151.031 101.268 1.00 38.20  ? 60  LYS Q NZ  1 
ATOM   4575 N N   . PRO C 3 61  ? 143.314 155.078 101.917 1.00 39.42  ? 61  PRO Q N   1 
ATOM   4576 C CA  . PRO C 3 61  ? 144.121 156.305 101.840 1.00 31.74  ? 61  PRO Q CA  1 
ATOM   4577 C C   . PRO C 3 61  ? 143.404 157.483 102.480 1.00 35.85  ? 61  PRO Q C   1 
ATOM   4578 O O   . PRO C 3 61  ? 142.307 157.866 102.069 1.00 39.44  ? 61  PRO Q O   1 
ATOM   4579 C CB  . PRO C 3 61  ? 144.315 156.504 100.333 1.00 37.84  ? 61  PRO Q CB  1 
ATOM   4580 C CG  . PRO C 3 61  ? 143.211 155.730 99.698  1.00 37.38  ? 61  PRO Q CG  1 
ATOM   4581 C CD  . PRO C 3 61  ? 143.001 154.546 100.581 1.00 38.91  ? 61  PRO Q CD  1 
ATOM   4582 N N   . GLY C 3 62  ? 144.036 158.058 103.499 1.00 38.67  ? 62  GLY Q N   1 
ATOM   4583 C CA  . GLY C 3 62  ? 143.494 159.219 104.174 1.00 36.02  ? 62  GLY Q CA  1 
ATOM   4584 C C   . GLY C 3 62  ? 142.531 158.938 105.303 1.00 37.01  ? 62  GLY Q C   1 
ATOM   4585 O O   . GLY C 3 62  ? 141.772 159.835 105.683 1.00 43.06  ? 62  GLY Q O   1 
ATOM   4586 N N   . LYS C 3 63  ? 142.530 157.725 105.854 1.00 27.98  ? 63  LYS Q N   1 
ATOM   4587 C CA  . LYS C 3 63  ? 141.623 157.372 106.936 1.00 22.04  ? 63  LYS Q CA  1 
ATOM   4588 C C   . LYS C 3 63  ? 142.371 156.559 107.983 1.00 22.72  ? 63  LYS Q C   1 
ATOM   4589 O O   . LYS C 3 63  ? 143.542 156.213 107.817 1.00 31.98  ? 63  LYS Q O   1 
ATOM   4590 C CB  . LYS C 3 63  ? 140.410 156.592 106.420 1.00 28.27  ? 63  LYS Q CB  1 
ATOM   4591 C CG  . LYS C 3 63  ? 139.508 157.386 105.492 1.00 26.97  ? 63  LYS Q CG  1 
ATOM   4592 C CD  . LYS C 3 63  ? 138.078 156.870 105.524 1.00 34.71  ? 63  LYS Q CD  1 
ATOM   4593 C CE  . LYS C 3 63  ? 137.905 155.627 104.664 1.00 36.27  ? 63  LYS Q CE  1 
ATOM   4594 N NZ  . LYS C 3 63  ? 138.311 154.380 105.371 1.00 31.31  ? 63  LYS Q NZ  1 
ATOM   4595 N N   . ALA C 3 64  ? 141.675 156.263 109.079 1.00 11.39  ? 64  ALA Q N   1 
ATOM   4596 C CA  . ALA C 3 64  ? 142.225 155.469 110.165 1.00 8.69   ? 64  ALA Q CA  1 
ATOM   4597 C C   . ALA C 3 64  ? 142.158 153.980 109.834 1.00 17.43  ? 64  ALA Q C   1 
ATOM   4598 O O   . ALA C 3 64  ? 141.310 153.549 109.048 1.00 26.40  ? 64  ALA Q O   1 
ATOM   4599 C CB  . ALA C 3 64  ? 141.469 155.740 111.458 1.00 5.12   ? 64  ALA Q CB  1 
ATOM   4600 N N   . PRO C 3 65  ? 143.048 153.175 110.413 1.00 9.63   ? 65  PRO Q N   1 
ATOM   4601 C CA  . PRO C 3 65  ? 142.992 151.729 110.177 1.00 0.00   ? 65  PRO Q CA  1 
ATOM   4602 C C   . PRO C 3 65  ? 141.705 151.118 110.707 1.00 0.00   ? 65  PRO Q C   1 
ATOM   4603 O O   . PRO C 3 65  ? 141.119 151.589 111.682 1.00 16.53  ? 65  PRO Q O   1 
ATOM   4604 C CB  . PRO C 3 65  ? 144.214 151.199 110.932 1.00 0.00   ? 65  PRO Q CB  1 
ATOM   4605 C CG  . PRO C 3 65  ? 145.136 152.359 111.010 1.00 6.50   ? 65  PRO Q CG  1 
ATOM   4606 C CD  . PRO C 3 65  ? 144.265 153.564 111.144 1.00 0.00   ? 65  PRO Q CD  1 
ATOM   4607 N N   . LYS C 3 66  ? 141.261 150.061 110.036 1.00 11.55  ? 66  LYS Q N   1 
ATOM   4608 C CA  . LYS C 3 66  ? 140.099 149.286 110.443 1.00 12.96  ? 66  LYS Q CA  1 
ATOM   4609 C C   . LYS C 3 66  ? 140.544 147.876 110.794 1.00 16.15  ? 66  LYS Q C   1 
ATOM   4610 O O   . LYS C 3 66  ? 141.250 147.236 110.011 1.00 25.20  ? 66  LYS Q O   1 
ATOM   4611 C CB  . LYS C 3 66  ? 139.048 149.248 109.334 1.00 5.61   ? 66  LYS Q CB  1 
ATOM   4612 C CG  . LYS C 3 66  ? 138.268 150.536 109.184 1.00 23.82  ? 66  LYS Q CG  1 
ATOM   4613 C CD  . LYS C 3 66  ? 137.089 150.361 108.249 1.00 23.95  ? 66  LYS Q CD  1 
ATOM   4614 C CE  . LYS C 3 66  ? 136.199 151.591 108.251 1.00 28.20  ? 66  LYS Q CE  1 
ATOM   4615 N NZ  . LYS C 3 66  ? 135.016 151.417 107.365 1.00 29.59  ? 66  LYS Q NZ  1 
ATOM   4616 N N   . LEU C 3 67  ? 140.133 147.397 111.965 1.00 6.46   ? 67  LEU Q N   1 
ATOM   4617 C CA  . LEU C 3 67  ? 140.516 146.063 112.411 1.00 3.28   ? 67  LEU Q CA  1 
ATOM   4618 C C   . LEU C 3 67  ? 139.793 145.009 111.582 1.00 22.79  ? 67  LEU Q C   1 
ATOM   4619 O O   . LEU C 3 67  ? 138.563 145.032 111.472 1.00 28.45  ? 67  LEU Q O   1 
ATOM   4620 C CB  . LEU C 3 67  ? 140.199 145.893 113.893 1.00 0.21   ? 67  LEU Q CB  1 
ATOM   4621 C CG  . LEU C 3 67  ? 140.402 144.508 114.504 1.00 4.49   ? 67  LEU Q CG  1 
ATOM   4622 C CD1 . LEU C 3 67  ? 141.870 144.200 114.704 1.00 0.46   ? 67  LEU Q CD1 1 
ATOM   4623 C CD2 . LEU C 3 67  ? 139.654 144.414 115.808 1.00 11.37  ? 67  LEU Q CD2 1 
ATOM   4624 N N   . LEU C 3 68  ? 140.555 144.089 110.990 1.00 13.30  ? 68  LEU Q N   1 
ATOM   4625 C CA  . LEU C 3 68  ? 139.984 143.028 110.167 1.00 15.18  ? 68  LEU Q CA  1 
ATOM   4626 C C   . LEU C 3 68  ? 139.796 141.731 110.947 1.00 19.50  ? 68  LEU Q C   1 
ATOM   4627 O O   . LEU C 3 68  ? 138.667 141.269 111.128 1.00 25.07  ? 68  LEU Q O   1 
ATOM   4628 C CB  . LEU C 3 68  ? 140.871 142.784 108.942 1.00 8.03   ? 68  LEU Q CB  1 
ATOM   4629 C CG  . LEU C 3 68  ? 140.866 143.873 107.875 1.00 8.22   ? 68  LEU Q CG  1 
ATOM   4630 C CD1 . LEU C 3 68  ? 141.672 143.424 106.679 1.00 17.10  ? 68  LEU Q CD1 1 
ATOM   4631 C CD2 . LEU C 3 68  ? 139.447 144.214 107.473 1.00 14.70  ? 68  LEU Q CD2 1 
ATOM   4632 N N   . ILE C 3 69  ? 140.890 141.132 111.415 1.00 20.52  ? 69  ILE Q N   1 
ATOM   4633 C CA  . ILE C 3 69  ? 140.842 139.890 112.172 1.00 3.14   ? 69  ILE Q CA  1 
ATOM   4634 C C   . ILE C 3 69  ? 141.791 140.012 113.353 1.00 9.27   ? 69  ILE Q C   1 
ATOM   4635 O O   . ILE C 3 69  ? 142.707 140.835 113.361 1.00 29.10  ? 69  ILE Q O   1 
ATOM   4636 C CB  . ILE C 3 69  ? 141.198 138.647 111.312 1.00 13.92  ? 69  ILE Q CB  1 
ATOM   4637 C CG1 . ILE C 3 69  ? 142.701 138.557 111.054 1.00 9.18   ? 69  ILE Q CG1 1 
ATOM   4638 C CG2 . ILE C 3 69  ? 140.442 138.639 109.995 1.00 14.30  ? 69  ILE Q CG2 1 
ATOM   4639 C CD1 . ILE C 3 69  ? 143.415 137.547 111.916 1.00 18.61  ? 69  ILE Q CD1 1 
ATOM   4640 N N   . TYR C 3 70  ? 141.563 139.173 114.361 1.00 11.03  ? 70  TYR Q N   1 
ATOM   4641 C CA  . TYR C 3 70  ? 142.434 139.094 115.522 1.00 12.85  ? 70  TYR Q CA  1 
ATOM   4642 C C   . TYR C 3 70  ? 142.575 137.634 115.924 1.00 10.55  ? 70  TYR Q C   1 
ATOM   4643 O O   . TYR C 3 70  ? 141.873 136.759 115.413 1.00 14.90  ? 70  TYR Q O   1 
ATOM   4644 C CB  . TYR C 3 70  ? 141.908 139.938 116.690 1.00 5.55   ? 70  TYR Q CB  1 
ATOM   4645 C CG  . TYR C 3 70  ? 140.539 139.537 117.176 1.00 2.64   ? 70  TYR Q CG  1 
ATOM   4646 C CD1 . TYR C 3 70  ? 139.398 140.068 116.601 1.00 9.88   ? 70  TYR Q CD1 1 
ATOM   4647 C CD2 . TYR C 3 70  ? 140.387 138.629 118.211 1.00 10.58  ? 70  TYR Q CD2 1 
ATOM   4648 C CE1 . TYR C 3 70  ? 138.148 139.704 117.040 1.00 18.44  ? 70  TYR Q CE1 1 
ATOM   4649 C CE2 . TYR C 3 70  ? 139.141 138.261 118.656 1.00 3.98   ? 70  TYR Q CE2 1 
ATOM   4650 C CZ  . TYR C 3 70  ? 138.025 138.799 118.066 1.00 13.55  ? 70  TYR Q CZ  1 
ATOM   4651 O OH  . TYR C 3 70  ? 136.777 138.435 118.507 1.00 31.78  ? 70  TYR Q OH  1 
ATOM   4652 N N   . SER C 3 71  ? 143.506 137.376 116.842 1.00 4.28   ? 71  SER Q N   1 
ATOM   4653 C CA  . SER C 3 71  ? 143.850 136.028 117.292 1.00 13.04  ? 71  SER Q CA  1 
ATOM   4654 C C   . SER C 3 71  ? 144.351 135.152 116.151 1.00 13.46  ? 71  SER Q C   1 
ATOM   4655 O O   . SER C 3 71  ? 144.338 133.923 116.259 1.00 27.53  ? 71  SER Q O   1 
ATOM   4656 C CB  . SER C 3 71  ? 142.669 135.350 117.996 1.00 18.79  ? 71  SER Q CB  1 
ATOM   4657 O OG  . SER C 3 71  ? 142.457 135.904 119.280 1.00 24.44  ? 71  SER Q OG  1 
ATOM   4658 N N   . ALA C 3 72  ? 144.755 135.786 115.050 1.00 15.50  ? 72  ALA Q N   1 
ATOM   4659 C CA  . ALA C 3 72  ? 145.313 135.158 113.857 1.00 8.92   ? 72  ALA Q CA  1 
ATOM   4660 C C   . ALA C 3 72  ? 144.259 134.406 113.055 1.00 7.09   ? 72  ALA Q C   1 
ATOM   4661 O O   . ALA C 3 72  ? 144.528 133.986 111.928 1.00 19.66  ? 72  ALA Q O   1 
ATOM   4662 C CB  . ALA C 3 72  ? 146.466 134.221 114.220 1.00 7.56   ? 72  ALA Q CB  1 
ATOM   4663 N N   . SER C 3 73  ? 143.060 134.235 113.611 1.00 19.93  ? 73  SER Q N   1 
ATOM   4664 C CA  . SER C 3 73  ? 141.962 133.626 112.864 1.00 11.25  ? 73  SER Q CA  1 
ATOM   4665 C C   . SER C 3 73  ? 140.607 134.273 113.082 1.00 15.11  ? 73  SER Q C   1 
ATOM   4666 O O   . SER C 3 73  ? 139.761 134.182 112.187 1.00 14.21  ? 73  SER Q O   1 
ATOM   4667 C CB  . SER C 3 73  ? 141.845 132.136 113.201 1.00 10.77  ? 73  SER Q CB  1 
ATOM   4668 O OG  . SER C 3 73  ? 142.781 131.369 112.471 1.00 29.85  ? 73  SER Q OG  1 
ATOM   4669 N N   . SER C 3 74  ? 140.360 134.929 114.209 1.00 14.17  ? 74  SER Q N   1 
ATOM   4670 C CA  . SER C 3 74  ? 139.007 135.324 114.573 1.00 16.49  ? 74  SER Q CA  1 
ATOM   4671 C C   . SER C 3 74  ? 138.567 136.505 113.721 1.00 16.91  ? 74  SER Q C   1 
ATOM   4672 O O   . SER C 3 74  ? 139.246 137.534 113.673 1.00 16.31  ? 74  SER Q O   1 
ATOM   4673 C CB  . SER C 3 74  ? 138.928 135.665 116.057 1.00 21.25  ? 74  SER Q CB  1 
ATOM   4674 O OG  . SER C 3 74  ? 137.589 135.897 116.452 1.00 26.32  ? 74  SER Q OG  1 
ATOM   4675 N N   . LEU C 3 75  ? 137.428 136.352 113.059 1.00 24.24  ? 75  LEU Q N   1 
ATOM   4676 C CA  . LEU C 3 75  ? 136.902 137.375 112.168 1.00 21.43  ? 75  LEU Q CA  1 
ATOM   4677 C C   . LEU C 3 75  ? 136.138 138.407 112.987 1.00 25.47  ? 75  LEU Q C   1 
ATOM   4678 O O   . LEU C 3 75  ? 135.131 138.080 113.624 1.00 32.96  ? 75  LEU Q O   1 
ATOM   4679 C CB  . LEU C 3 75  ? 136.012 136.717 111.115 1.00 23.85  ? 75  LEU Q CB  1 
ATOM   4680 C CG  . LEU C 3 75  ? 135.724 137.382 109.771 1.00 27.34  ? 75  LEU Q CG  1 
ATOM   4681 C CD1 . LEU C 3 75  ? 134.835 138.585 109.933 1.00 29.25  ? 75  LEU Q CD1 1 
ATOM   4682 C CD2 . LEU C 3 75  ? 137.021 137.771 109.107 1.00 26.97  ? 75  LEU Q CD2 1 
ATOM   4683 N N   . TYR C 3 76  ? 136.620 139.646 112.977 1.00 30.99  ? 76  TYR Q N   1 
ATOM   4684 C CA  . TYR C 3 76  ? 136.002 140.702 113.762 1.00 24.42  ? 76  TYR Q CA  1 
ATOM   4685 C C   . TYR C 3 76  ? 134.586 140.973 113.272 1.00 27.86  ? 76  TYR Q C   1 
ATOM   4686 O O   . TYR C 3 76  ? 134.289 140.874 112.080 1.00 36.68  ? 76  TYR Q O   1 
ATOM   4687 C CB  . TYR C 3 76  ? 136.837 141.980 113.694 1.00 19.21  ? 76  TYR Q CB  1 
ATOM   4688 C CG  . TYR C 3 76  ? 136.291 143.106 114.538 1.00 30.09  ? 76  TYR Q CG  1 
ATOM   4689 C CD1 . TYR C 3 76  ? 136.225 142.993 115.918 1.00 33.73  ? 76  TYR Q CD1 1 
ATOM   4690 C CD2 . TYR C 3 76  ? 135.834 144.277 113.956 1.00 28.67  ? 76  TYR Q CD2 1 
ATOM   4691 C CE1 . TYR C 3 76  ? 135.721 144.015 116.693 1.00 26.74  ? 76  TYR Q CE1 1 
ATOM   4692 C CE2 . TYR C 3 76  ? 135.329 145.304 114.724 1.00 27.36  ? 76  TYR Q CE2 1 
ATOM   4693 C CZ  . TYR C 3 76  ? 135.275 145.167 116.092 1.00 25.44  ? 76  TYR Q CZ  1 
ATOM   4694 O OH  . TYR C 3 76  ? 134.772 146.188 116.862 1.00 30.26  ? 76  TYR Q OH  1 
ATOM   4695 N N   . SER C 3 77  ? 133.705 141.306 114.212 1.00 34.09  ? 77  SER Q N   1 
ATOM   4696 C CA  . SER C 3 77  ? 132.301 141.511 113.883 1.00 39.05  ? 77  SER Q CA  1 
ATOM   4697 C C   . SER C 3 77  ? 132.141 142.655 112.890 1.00 39.56  ? 77  SER Q C   1 
ATOM   4698 O O   . SER C 3 77  ? 132.714 143.733 113.067 1.00 36.82  ? 77  SER Q O   1 
ATOM   4699 C CB  . SER C 3 77  ? 131.502 141.797 115.153 1.00 37.98  ? 77  SER Q CB  1 
ATOM   4700 N N   . GLY C 3 78  ? 131.352 142.414 111.844 1.00 36.79  ? 78  GLY Q N   1 
ATOM   4701 C CA  . GLY C 3 78  ? 131.119 143.387 110.804 1.00 36.70  ? 78  GLY Q CA  1 
ATOM   4702 C C   . GLY C 3 78  ? 132.034 143.272 109.603 1.00 36.94  ? 78  GLY Q C   1 
ATOM   4703 O O   . GLY C 3 78  ? 131.707 143.810 108.540 1.00 42.99  ? 78  GLY Q O   1 
ATOM   4704 N N   . VAL C 3 79  ? 133.163 142.592 109.738 1.00 32.37  ? 79  VAL Q N   1 
ATOM   4705 C CA  . VAL C 3 79  ? 134.081 142.420 108.606 1.00 30.57  ? 79  VAL Q CA  1 
ATOM   4706 C C   . VAL C 3 79  ? 133.478 141.426 107.621 1.00 33.23  ? 79  VAL Q C   1 
ATOM   4707 O O   . VAL C 3 79  ? 132.896 140.414 108.051 1.00 37.12  ? 79  VAL Q O   1 
ATOM   4708 C CB  . VAL C 3 79  ? 135.449 141.949 109.104 1.00 32.90  ? 79  VAL Q CB  1 
ATOM   4709 C CG1 . VAL C 3 79  ? 136.412 141.754 107.949 1.00 32.65  ? 79  VAL Q CG1 1 
ATOM   4710 C CG2 . VAL C 3 79  ? 136.010 142.937 110.106 1.00 37.06  ? 79  VAL Q CG2 1 
ATOM   4711 N N   . PRO C 3 80  ? 133.566 141.669 106.313 1.00 35.15  ? 80  PRO Q N   1 
ATOM   4712 C CA  . PRO C 3 80  ? 133.040 140.697 105.348 1.00 36.33  ? 80  PRO Q CA  1 
ATOM   4713 C C   . PRO C 3 80  ? 133.752 139.357 105.455 1.00 40.83  ? 80  PRO Q C   1 
ATOM   4714 O O   . PRO C 3 80  ? 134.926 139.275 105.819 1.00 36.19  ? 80  PRO Q O   1 
ATOM   4715 C CB  . PRO C 3 80  ? 133.304 141.364 103.995 1.00 33.68  ? 80  PRO Q CB  1 
ATOM   4716 C CG  . PRO C 3 80  ? 133.350 142.815 104.302 1.00 37.27  ? 80  PRO Q CG  1 
ATOM   4717 C CD  . PRO C 3 80  ? 133.971 142.926 105.662 1.00 37.16  ? 80  PRO Q CD  1 
ATOM   4718 N N   . SER C 3 81  ? 133.014 138.295 105.128 1.00 41.23  ? 81  SER Q N   1 
ATOM   4719 C CA  . SER C 3 81  ? 133.512 136.934 105.277 1.00 39.24  ? 81  SER Q CA  1 
ATOM   4720 C C   . SER C 3 81  ? 134.626 136.590 104.299 1.00 42.63  ? 81  SER Q C   1 
ATOM   4721 O O   . SER C 3 81  ? 135.249 135.535 104.453 1.00 43.71  ? 81  SER Q O   1 
ATOM   4722 C CB  . SER C 3 81  ? 132.363 135.940 105.115 1.00 39.51  ? 81  SER Q CB  1 
ATOM   4723 O OG  . SER C 3 81  ? 131.161 136.465 105.650 1.00 43.67  ? 81  SER Q OG  1 
ATOM   4724 N N   . ARG C 3 82  ? 134.881 137.434 103.296 1.00 38.34  ? 82  ARG Q N   1 
ATOM   4725 C CA  . ARG C 3 82  ? 135.967 137.160 102.361 1.00 38.21  ? 82  ARG Q CA  1 
ATOM   4726 C C   . ARG C 3 82  ? 137.313 137.137 103.070 1.00 41.66  ? 82  ARG Q C   1 
ATOM   4727 O O   . ARG C 3 82  ? 138.152 136.271 102.797 1.00 45.56  ? 82  ARG Q O   1 
ATOM   4728 C CB  . ARG C 3 82  ? 135.973 138.198 101.241 1.00 41.70  ? 82  ARG Q CB  1 
ATOM   4729 C CG  . ARG C 3 82  ? 134.596 138.619 100.772 1.00 42.34  ? 82  ARG Q CG  1 
ATOM   4730 C CD  . ARG C 3 82  ? 134.669 139.863 99.905  1.00 38.86  ? 82  ARG Q CD  1 
ATOM   4731 N NE  . ARG C 3 82  ? 134.216 141.053 100.613 1.00 43.74  ? 82  ARG Q NE  1 
ATOM   4732 C CZ  . ARG C 3 82  ? 134.761 142.253 100.482 1.00 47.20  ? 82  ARG Q CZ  1 
ATOM   4733 N NH1 . ARG C 3 82  ? 135.809 142.454 99.703  1.00 44.75  ? 82  ARG Q NH1 1 
ATOM   4734 N NH2 . ARG C 3 82  ? 134.243 143.278 101.152 1.00 45.07  ? 82  ARG Q NH2 1 
ATOM   4735 N N   . PHE C 3 83  ? 137.539 138.079 103.980 1.00 23.73  ? 83  PHE Q N   1 
ATOM   4736 C CA  . PHE C 3 83  ? 138.784 138.107 104.732 1.00 24.52  ? 83  PHE Q CA  1 
ATOM   4737 C C   . PHE C 3 83  ? 138.870 136.904 105.660 1.00 24.61  ? 83  PHE Q C   1 
ATOM   4738 O O   . PHE C 3 83  ? 137.890 136.526 106.306 1.00 31.56  ? 83  PHE Q O   1 
ATOM   4739 C CB  . PHE C 3 83  ? 138.889 139.401 105.536 1.00 29.31  ? 83  PHE Q CB  1 
ATOM   4740 C CG  . PHE C 3 83  ? 138.855 140.641 104.694 1.00 29.63  ? 83  PHE Q CG  1 
ATOM   4741 C CD1 . PHE C 3 83  ? 139.981 141.063 104.014 1.00 27.46  ? 83  PHE Q CD1 1 
ATOM   4742 C CD2 . PHE C 3 83  ? 137.695 141.384 104.581 1.00 32.02  ? 83  PHE Q CD2 1 
ATOM   4743 C CE1 . PHE C 3 83  ? 139.951 142.200 103.240 1.00 26.54  ? 83  PHE Q CE1 1 
ATOM   4744 C CE2 . PHE C 3 83  ? 137.661 142.522 103.808 1.00 29.40  ? 83  PHE Q CE2 1 
ATOM   4745 C CZ  . PHE C 3 83  ? 138.790 142.930 103.137 1.00 27.79  ? 83  PHE Q CZ  1 
ATOM   4746 N N   . SER C 3 84  ? 140.048 136.293 105.716 1.00 23.80  ? 84  SER Q N   1 
ATOM   4747 C CA  . SER C 3 84  ? 140.266 135.153 106.593 1.00 25.90  ? 84  SER Q CA  1 
ATOM   4748 C C   . SER C 3 84  ? 141.750 135.055 106.905 1.00 29.91  ? 84  SER Q C   1 
ATOM   4749 O O   . SER C 3 84  ? 142.586 135.216 106.016 1.00 28.15  ? 84  SER Q O   1 
ATOM   4750 C CB  . SER C 3 84  ? 139.767 133.850 105.960 1.00 32.76  ? 84  SER Q CB  1 
ATOM   4751 O OG  . SER C 3 84  ? 140.586 133.459 104.872 1.00 33.43  ? 84  SER Q OG  1 
ATOM   4752 N N   . GLY C 3 85  ? 142.063 134.792 108.169 1.00 26.12  ? 85  GLY Q N   1 
ATOM   4753 C CA  . GLY C 3 85  ? 143.441 134.656 108.590 1.00 15.79  ? 85  GLY Q CA  1 
ATOM   4754 C C   . GLY C 3 85  ? 143.754 133.271 109.111 1.00 24.54  ? 85  GLY Q C   1 
ATOM   4755 O O   . GLY C 3 85  ? 142.855 132.557 109.560 1.00 25.14  ? 85  GLY Q O   1 
ATOM   4756 N N   . SER C 3 86  ? 145.023 132.876 109.056 1.00 26.31  ? 86  SER Q N   1 
ATOM   4757 C CA  . SER C 3 86  ? 145.433 131.578 109.565 1.00 19.51  ? 86  SER Q CA  1 
ATOM   4758 C C   . SER C 3 86  ? 146.875 131.657 110.037 1.00 13.45  ? 86  SER Q C   1 
ATOM   4759 O O   . SER C 3 86  ? 147.644 132.511 109.592 1.00 26.95  ? 86  SER Q O   1 
ATOM   4760 C CB  . SER C 3 86  ? 145.284 130.481 108.505 1.00 21.78  ? 86  SER Q CB  1 
ATOM   4761 O OG  . SER C 3 86  ? 146.230 130.640 107.464 1.00 24.03  ? 86  SER Q OG  1 
ATOM   4762 N N   . ARG C 3 87  ? 147.233 130.755 110.945 1.00 17.90  ? 87  ARG Q N   1 
ATOM   4763 C CA  . ARG C 3 87  ? 148.587 130.652 111.468 1.00 20.83  ? 87  ARG Q CA  1 
ATOM   4764 C C   . ARG C 3 87  ? 149.094 129.234 111.269 1.00 25.49  ? 87  ARG Q C   1 
ATOM   4765 O O   . ARG C 3 87  ? 148.423 128.272 111.654 1.00 33.39  ? 87  ARG Q O   1 
ATOM   4766 C CB  . ARG C 3 87  ? 148.640 131.018 112.951 1.00 21.82  ? 87  ARG Q CB  1 
ATOM   4767 C CG  . ARG C 3 87  ? 149.920 130.586 113.636 1.00 12.63  ? 87  ARG Q CG  1 
ATOM   4768 C CD  . ARG C 3 87  ? 149.703 130.341 115.112 1.00 12.74  ? 87  ARG Q CD  1 
ATOM   4769 N NE  . ARG C 3 87  ? 150.968 130.170 115.812 1.00 21.67  ? 87  ARG Q NE  1 
ATOM   4770 C CZ  . ARG C 3 87  ? 151.080 129.807 117.081 1.00 23.32  ? 87  ARG Q CZ  1 
ATOM   4771 N NH1 . ARG C 3 87  ? 150.015 129.575 117.828 1.00 33.11  ? 87  ARG Q NH1 1 
ATOM   4772 N NH2 . ARG C 3 87  ? 152.290 129.676 117.614 1.00 16.86  ? 87  ARG Q NH2 1 
ATOM   4773 N N   . SER C 3 88  ? 150.274 129.106 110.667 1.00 23.18  ? 88  SER Q N   1 
ATOM   4774 C CA  . SER C 3 88  ? 150.928 127.811 110.527 1.00 29.87  ? 88  SER Q CA  1 
ATOM   4775 C C   . SER C 3 88  ? 152.012 127.625 111.582 1.00 33.33  ? 88  SER Q C   1 
ATOM   4776 O O   . SER C 3 88  ? 151.970 126.673 112.365 1.00 44.28  ? 88  SER Q O   1 
ATOM   4777 C CB  . SER C 3 88  ? 151.517 127.661 109.119 1.00 34.24  ? 88  SER Q CB  1 
ATOM   4778 O OG  . SER C 3 88  ? 152.315 126.493 109.028 1.00 36.07  ? 88  SER Q OG  1 
ATOM   4779 N N   . GLY C 3 89  ? 152.980 128.530 111.620 1.00 14.66  ? 89  GLY Q N   1 
ATOM   4780 C CA  . GLY C 3 89  ? 154.007 128.489 112.637 1.00 24.38  ? 89  GLY Q CA  1 
ATOM   4781 C C   . GLY C 3 89  ? 154.273 129.868 113.194 1.00 36.70  ? 89  GLY Q C   1 
ATOM   4782 O O   . GLY C 3 89  ? 153.379 130.512 113.749 1.00 35.01  ? 89  GLY Q O   1 
ATOM   4783 N N   . THR C 3 90  ? 155.517 130.323 113.066 1.00 37.90  ? 90  THR Q N   1 
ATOM   4784 C CA  . THR C 3 90  ? 155.833 131.709 113.372 1.00 16.15  ? 90  THR Q CA  1 
ATOM   4785 C C   . THR C 3 90  ? 155.249 132.662 112.338 1.00 18.97  ? 90  THR Q C   1 
ATOM   4786 O O   . THR C 3 90  ? 155.173 133.868 112.592 1.00 37.54  ? 90  THR Q O   1 
ATOM   4787 C CB  . THR C 3 90  ? 157.347 131.881 113.463 1.00 24.33  ? 90  THR Q CB  1 
ATOM   4788 O OG1 . THR C 3 90  ? 157.910 130.749 114.135 1.00 35.11  ? 90  THR Q OG1 1 
ATOM   4789 C CG2 . THR C 3 90  ? 157.698 133.122 114.244 1.00 29.42  ? 90  THR Q CG2 1 
ATOM   4790 N N   . ASP C 3 91  ? 154.832 132.153 111.187 1.00 21.58  ? 91  ASP Q N   1 
ATOM   4791 C CA  . ASP C 3 91  ? 154.271 132.973 110.127 1.00 20.52  ? 91  ASP Q CA  1 
ATOM   4792 C C   . ASP C 3 91  ? 152.746 133.001 110.183 1.00 23.72  ? 91  ASP Q C   1 
ATOM   4793 O O   . ASP C 3 91  ? 152.097 132.104 110.727 1.00 28.09  ? 91  ASP Q O   1 
ATOM   4794 C CB  . ASP C 3 91  ? 154.811 132.514 108.755 1.00 25.06  ? 91  ASP Q CB  1 
ATOM   4795 C CG  . ASP C 3 91  ? 153.980 131.419 108.065 1.00 31.10  ? 91  ASP Q CG  1 
ATOM   4796 O OD1 . ASP C 3 91  ? 152.955 130.928 108.570 1.00 30.32  ? 91  ASP Q OD1 1 
ATOM   4797 O OD2 . ASP C 3 91  ? 154.415 130.989 106.979 1.00 39.68  ? 91  ASP Q OD2 1 
ATOM   4798 N N   . PHE C 3 92  ? 152.185 134.071 109.629 1.00 28.07  ? 92  PHE Q N   1 
ATOM   4799 C CA  . PHE C 3 92  ? 150.751 134.298 109.614 1.00 20.56  ? 92  PHE Q CA  1 
ATOM   4800 C C   . PHE C 3 92  ? 150.345 134.755 108.221 1.00 22.91  ? 92  PHE Q C   1 
ATOM   4801 O O   . PHE C 3 92  ? 151.148 135.317 107.477 1.00 24.11  ? 92  PHE Q O   1 
ATOM   4802 C CB  . PHE C 3 92  ? 150.333 135.337 110.664 1.00 19.85  ? 92  PHE Q CB  1 
ATOM   4803 C CG  . PHE C 3 92  ? 150.733 134.978 112.067 1.00 17.76  ? 92  PHE Q CG  1 
ATOM   4804 C CD1 . PHE C 3 92  ? 152.013 135.224 112.523 1.00 11.75  ? 92  PHE Q CD1 1 
ATOM   4805 C CD2 . PHE C 3 92  ? 149.829 134.395 112.929 1.00 21.01  ? 92  PHE Q CD2 1 
ATOM   4806 C CE1 . PHE C 3 92  ? 152.380 134.894 113.803 1.00 14.78  ? 92  PHE Q CE1 1 
ATOM   4807 C CE2 . PHE C 3 92  ? 150.193 134.068 114.215 1.00 15.95  ? 92  PHE Q CE2 1 
ATOM   4808 C CZ  . PHE C 3 92  ? 151.470 134.316 114.649 1.00 14.24  ? 92  PHE Q CZ  1 
ATOM   4809 N N   . THR C 3 93  ? 149.088 134.499 107.869 1.00 20.21  ? 93  THR Q N   1 
ATOM   4810 C CA  . THR C 3 93  ? 148.601 134.760 106.524 1.00 12.70  ? 93  THR Q CA  1 
ATOM   4811 C C   . THR C 3 93  ? 147.204 135.352 106.579 1.00 18.67  ? 93  THR Q C   1 
ATOM   4812 O O   . THR C 3 93  ? 146.351 134.875 107.329 1.00 28.07  ? 93  THR Q O   1 
ATOM   4813 C CB  . THR C 3 93  ? 148.578 133.478 105.681 1.00 20.27  ? 93  THR Q CB  1 
ATOM   4814 O OG1 . THR C 3 93  ? 149.804 132.759 105.861 1.00 25.00  ? 93  THR Q OG1 1 
ATOM   4815 C CG2 . THR C 3 93  ? 148.403 133.805 104.215 1.00 16.90  ? 93  THR Q CG2 1 
ATOM   4816 N N   . LEU C 3 94  ? 146.978 136.393 105.784 1.00 23.47  ? 94  LEU Q N   1 
ATOM   4817 C CA  . LEU C 3 94  ? 145.649 136.946 105.558 1.00 13.82  ? 94  LEU Q CA  1 
ATOM   4818 C C   . LEU C 3 94  ? 145.298 136.725 104.096 1.00 20.50  ? 94  LEU Q C   1 
ATOM   4819 O O   . LEU C 3 94  ? 146.043 137.147 103.207 1.00 22.51  ? 94  LEU Q O   1 
ATOM   4820 C CB  . LEU C 3 94  ? 145.590 138.434 105.908 1.00 15.15  ? 94  LEU Q CB  1 
ATOM   4821 C CG  . LEU C 3 94  ? 144.288 139.163 105.561 1.00 15.54  ? 94  LEU Q CG  1 
ATOM   4822 C CD1 . LEU C 3 94  ? 143.346 139.213 106.748 1.00 14.99  ? 94  LEU Q CD1 1 
ATOM   4823 C CD2 . LEU C 3 94  ? 144.574 140.560 105.048 1.00 21.91  ? 94  LEU Q CD2 1 
ATOM   4824 N N   . THR C 3 95  ? 144.176 136.057 103.850 1.00 33.93  ? 95  THR Q N   1 
ATOM   4825 C CA  . THR C 3 95  ? 143.730 135.746 102.502 1.00 38.91  ? 95  THR Q CA  1 
ATOM   4826 C C   . THR C 3 95  ? 142.413 136.451 102.225 1.00 35.65  ? 95  THR Q C   1 
ATOM   4827 O O   . THR C 3 95  ? 141.569 136.587 103.115 1.00 29.15  ? 95  THR Q O   1 
ATOM   4828 C CB  . THR C 3 95  ? 143.556 134.238 102.295 1.00 32.95  ? 95  THR Q CB  1 
ATOM   4829 O OG1 . THR C 3 95  ? 142.244 133.848 102.715 1.00 35.30  ? 95  THR Q OG1 1 
ATOM   4830 C CG2 . THR C 3 95  ? 144.584 133.465 103.098 1.00 37.19  ? 95  THR Q CG2 1 
ATOM   4831 N N   . ILE C 3 96  ? 142.250 136.910 100.989 1.00 41.20  ? 96  ILE Q N   1 
ATOM   4832 C CA  . ILE C 3 96  ? 141.008 137.509 100.523 1.00 38.24  ? 96  ILE Q CA  1 
ATOM   4833 C C   . ILE C 3 96  ? 140.501 136.665 99.366  1.00 43.89  ? 96  ILE Q C   1 
ATOM   4834 O O   . ILE C 3 96  ? 141.219 136.460 98.379  1.00 46.28  ? 96  ILE Q O   1 
ATOM   4835 C CB  . ILE C 3 96  ? 141.199 138.971 100.096 1.00 37.09  ? 96  ILE Q CB  1 
ATOM   4836 C CG1 . ILE C 3 96  ? 142.047 139.722 101.124 1.00 45.55  ? 96  ILE Q CG1 1 
ATOM   4837 C CG2 . ILE C 3 96  ? 139.856 139.646 99.925  1.00 38.57  ? 96  ILE Q CG2 1 
ATOM   4838 C CD1 . ILE C 3 96  ? 142.549 141.063 100.641 1.00 39.79  ? 96  ILE Q CD1 1 
ATOM   4839 N N   . SER C 3 97  ? 139.273 136.172 99.486  1.00 48.33  ? 97  SER Q N   1 
ATOM   4840 C CA  . SER C 3 97  ? 138.647 135.363 98.450  1.00 50.57  ? 97  SER Q CA  1 
ATOM   4841 C C   . SER C 3 97  ? 137.690 136.239 97.655  1.00 51.43  ? 97  SER Q C   1 
ATOM   4842 O O   . SER C 3 97  ? 136.780 136.847 98.229  1.00 49.10  ? 97  SER Q O   1 
ATOM   4843 C CB  . SER C 3 97  ? 137.910 134.170 99.057  1.00 51.40  ? 97  SER Q CB  1 
ATOM   4844 O OG  . SER C 3 97  ? 138.811 133.298 99.716  1.00 52.10  ? 97  SER Q OG  1 
ATOM   4845 N N   . SER C 3 98  ? 137.899 136.302 96.342  1.00 50.11  ? 98  SER Q N   1 
ATOM   4846 C CA  . SER C 3 98  ? 137.074 137.098 95.437  1.00 51.78  ? 98  SER Q CA  1 
ATOM   4847 C C   . SER C 3 98  ? 137.022 138.554 95.895  1.00 52.21  ? 98  SER Q C   1 
ATOM   4848 O O   . SER C 3 98  ? 135.978 139.078 96.286  1.00 55.78  ? 98  SER Q O   1 
ATOM   4849 C CB  . SER C 3 98  ? 135.669 136.507 95.313  1.00 52.60  ? 98  SER Q CB  1 
ATOM   4850 O OG  . SER C 3 98  ? 134.881 136.832 96.443  1.00 54.81  ? 98  SER Q OG  1 
ATOM   4851 N N   . LEU C 3 99  ? 138.185 139.198 95.855  1.00 48.77  ? 99  LEU Q N   1 
ATOM   4852 C CA  . LEU C 3 99  ? 138.288 140.569 96.333  1.00 51.69  ? 99  LEU Q CA  1 
ATOM   4853 C C   . LEU C 3 99  ? 137.433 141.499 95.483  1.00 49.76  ? 99  LEU Q C   1 
ATOM   4854 O O   . LEU C 3 99  ? 137.440 141.424 94.252  1.00 54.10  ? 99  LEU Q O   1 
ATOM   4855 C CB  . LEU C 3 99  ? 139.755 141.016 96.344  1.00 50.59  ? 99  LEU Q CB  1 
ATOM   4856 C CG  . LEU C 3 99  ? 140.531 141.518 95.119  1.00 50.53  ? 99  LEU Q CG  1 
ATOM   4857 C CD1 . LEU C 3 99  ? 140.212 142.964 94.760  1.00 52.03  ? 99  LEU Q CD1 1 
ATOM   4858 C CD2 . LEU C 3 99  ? 142.020 141.356 95.356  1.00 51.05  ? 99  LEU Q CD2 1 
ATOM   4859 N N   . GLN C 3 100 ? 136.687 142.360 96.149  1.00 47.82  ? 100 GLN Q N   1 
ATOM   4860 C CA  . GLN C 3 100 ? 135.854 143.380 95.537  1.00 47.10  ? 100 GLN Q CA  1 
ATOM   4861 C C   . GLN C 3 100 ? 136.657 144.655 95.317  1.00 52.47  ? 100 GLN Q C   1 
ATOM   4862 O O   . GLN C 3 100 ? 137.753 144.811 95.864  1.00 52.78  ? 100 GLN Q O   1 
ATOM   4863 C CB  . GLN C 3 100 ? 134.638 143.650 96.419  1.00 45.36  ? 100 GLN Q CB  1 
ATOM   4864 C CG  . GLN C 3 100 ? 133.994 142.400 97.002  1.00 48.31  ? 100 GLN Q CG  1 
ATOM   4865 C CD  . GLN C 3 100 ? 133.119 141.657 96.004  1.00 53.78  ? 100 GLN Q CD  1 
ATOM   4866 O OE1 . GLN C 3 100 ? 133.519 141.407 94.867  1.00 54.01  ? 100 GLN Q OE1 1 
ATOM   4867 N NE2 . GLN C 3 100 ? 131.913 141.302 96.431  1.00 54.21  ? 100 GLN Q NE2 1 
ATOM   4868 N N   . PRO C 3 101 ? 136.155 145.581 94.493  1.00 61.52  ? 101 PRO Q N   1 
ATOM   4869 C CA  . PRO C 3 101 ? 136.931 146.802 94.214  1.00 60.34  ? 101 PRO Q CA  1 
ATOM   4870 C C   . PRO C 3 101 ? 137.263 147.630 95.445  1.00 58.30  ? 101 PRO Q C   1 
ATOM   4871 O O   . PRO C 3 101 ? 138.285 148.328 95.441  1.00 59.11  ? 101 PRO Q O   1 
ATOM   4872 C CB  . PRO C 3 101 ? 136.029 147.578 93.240  1.00 58.88  ? 101 PRO Q CB  1 
ATOM   4873 C CG  . PRO C 3 101 ? 134.688 146.911 93.310  1.00 57.29  ? 101 PRO Q CG  1 
ATOM   4874 C CD  . PRO C 3 101 ? 134.975 145.485 93.618  1.00 56.83  ? 101 PRO Q CD  1 
ATOM   4875 N N   . GLU C 3 102 ? 136.446 147.581 96.499  1.00 54.76  ? 102 GLU Q N   1 
ATOM   4876 C CA  . GLU C 3 102 ? 136.730 148.341 97.710  1.00 52.21  ? 102 GLU Q CA  1 
ATOM   4877 C C   . GLU C 3 102 ? 137.719 147.641 98.637  1.00 49.96  ? 102 GLU Q C   1 
ATOM   4878 O O   . GLU C 3 102 ? 137.815 148.013 99.811  1.00 48.71  ? 102 GLU Q O   1 
ATOM   4879 C CB  . GLU C 3 102 ? 135.442 148.663 98.481  1.00 52.93  ? 102 GLU Q CB  1 
ATOM   4880 C CG  . GLU C 3 102 ? 134.532 147.493 98.877  1.00 52.58  ? 102 GLU Q CG  1 
ATOM   4881 C CD  . GLU C 3 102 ? 133.904 146.746 97.711  1.00 58.72  ? 102 GLU Q CD  1 
ATOM   4882 O OE1 . GLU C 3 102 ? 134.256 147.010 96.542  1.00 56.40  ? 102 GLU Q OE1 1 
ATOM   4883 O OE2 . GLU C 3 102 ? 133.035 145.888 97.971  1.00 61.41  ? 102 GLU Q OE2 1 
ATOM   4884 N N   . ASP C 3 103 ? 138.443 146.637 98.150  1.00 42.35  ? 103 ASP Q N   1 
ATOM   4885 C CA  . ASP C 3 103 ? 139.537 146.032 98.896  1.00 39.45  ? 103 ASP Q CA  1 
ATOM   4886 C C   . ASP C 3 103 ? 140.879 146.676 98.587  1.00 43.42  ? 103 ASP Q C   1 
ATOM   4887 O O   . ASP C 3 103 ? 141.903 146.230 99.112  1.00 40.28  ? 103 ASP Q O   1 
ATOM   4888 C CB  . ASP C 3 103 ? 139.607 144.533 98.610  1.00 40.00  ? 103 ASP Q CB  1 
ATOM   4889 C CG  . ASP C 3 103 ? 138.514 143.762 99.308  1.00 47.08  ? 103 ASP Q CG  1 
ATOM   4890 O OD1 . ASP C 3 103 ? 137.524 144.388 99.741  1.00 44.29  ? 103 ASP Q OD1 1 
ATOM   4891 O OD2 . ASP C 3 103 ? 138.638 142.527 99.424  1.00 50.49  ? 103 ASP Q OD2 1 
ATOM   4892 N N   . PHE C 3 104 ? 140.893 147.701 97.740  1.00 42.21  ? 104 PHE Q N   1 
ATOM   4893 C CA  . PHE C 3 104 ? 142.085 148.501 97.496  1.00 36.76  ? 104 PHE Q CA  1 
ATOM   4894 C C   . PHE C 3 104 ? 142.410 149.266 98.772  1.00 39.58  ? 104 PHE Q C   1 
ATOM   4895 O O   . PHE C 3 104 ? 141.715 150.226 99.120  1.00 39.69  ? 104 PHE Q O   1 
ATOM   4896 C CB  . PHE C 3 104 ? 141.828 149.447 96.324  1.00 44.56  ? 104 PHE Q CB  1 
ATOM   4897 C CG  . PHE C 3 104 ? 143.035 150.244 95.871  1.00 47.45  ? 104 PHE Q CG  1 
ATOM   4898 C CD1 . PHE C 3 104 ? 144.233 150.220 96.565  1.00 40.76  ? 104 PHE Q CD1 1 
ATOM   4899 C CD2 . PHE C 3 104 ? 142.948 151.038 94.739  1.00 46.26  ? 104 PHE Q CD2 1 
ATOM   4900 C CE1 . PHE C 3 104 ? 145.313 150.957 96.139  1.00 45.37  ? 104 PHE Q CE1 1 
ATOM   4901 C CE2 . PHE C 3 104 ? 144.027 151.777 94.307  1.00 48.84  ? 104 PHE Q CE2 1 
ATOM   4902 C CZ  . PHE C 3 104 ? 145.211 151.737 95.007  1.00 52.44  ? 104 PHE Q CZ  1 
ATOM   4903 N N   . ALA C 3 105 ? 143.461 148.853 99.462  1.00 23.44  ? 105 ALA Q N   1 
ATOM   4904 C CA  . ALA C 3 105 ? 143.880 149.492 100.705 1.00 12.82  ? 105 ALA Q CA  1 
ATOM   4905 C C   . ALA C 3 105 ? 145.288 149.012 101.029 1.00 16.08  ? 105 ALA Q C   1 
ATOM   4906 O O   . ALA C 3 105 ? 145.918 148.302 100.237 1.00 25.82  ? 105 ALA Q O   1 
ATOM   4907 C CB  . ALA C 3 105 ? 142.903 149.189 101.839 1.00 20.37  ? 105 ALA Q CB  1 
ATOM   4908 N N   . THR C 3 106 ? 145.784 149.412 102.194 1.00 24.32  ? 106 THR Q N   1 
ATOM   4909 C CA  . THR C 3 106 ? 147.038 148.925 102.747 1.00 18.26  ? 106 THR Q CA  1 
ATOM   4910 C C   . THR C 3 106 ? 146.724 148.117 103.995 1.00 17.36  ? 106 THR Q C   1 
ATOM   4911 O O   . THR C 3 106 ? 146.002 148.590 104.877 1.00 14.96  ? 106 THR Q O   1 
ATOM   4912 C CB  . THR C 3 106 ? 147.983 150.078 103.084 1.00 15.52  ? 106 THR Q CB  1 
ATOM   4913 O OG1 . THR C 3 106 ? 148.294 150.806 101.892 1.00 28.68  ? 106 THR Q OG1 1 
ATOM   4914 C CG2 . THR C 3 106 ? 149.266 149.557 103.692 1.00 19.28  ? 106 THR Q CG2 1 
ATOM   4915 N N   . TYR C 3 107 ? 147.252 146.900 104.065 1.00 13.55  ? 107 TYR Q N   1 
ATOM   4916 C CA  . TYR C 3 107 ? 146.922 145.969 105.132 1.00 6.65   ? 107 TYR Q CA  1 
ATOM   4917 C C   . TYR C 3 107 ? 148.115 145.795 106.058 1.00 15.81  ? 107 TYR Q C   1 
ATOM   4918 O O   . TYR C 3 107 ? 149.240 145.582 105.598 1.00 18.58  ? 107 TYR Q O   1 
ATOM   4919 C CB  . TYR C 3 107 ? 146.475 144.625 104.558 1.00 12.65  ? 107 TYR Q CB  1 
ATOM   4920 C CG  . TYR C 3 107 ? 145.259 144.753 103.678 1.00 8.20   ? 107 TYR Q CG  1 
ATOM   4921 C CD1 . TYR C 3 107 ? 145.385 145.009 102.325 1.00 20.32  ? 107 TYR Q CD1 1 
ATOM   4922 C CD2 . TYR C 3 107 ? 143.985 144.643 104.203 1.00 7.54   ? 107 TYR Q CD2 1 
ATOM   4923 C CE1 . TYR C 3 107 ? 144.280 145.136 101.521 1.00 23.54  ? 107 TYR Q CE1 1 
ATOM   4924 C CE2 . TYR C 3 107 ? 142.874 144.769 103.403 1.00 6.29   ? 107 TYR Q CE2 1 
ATOM   4925 C CZ  . TYR C 3 107 ? 143.028 145.018 102.064 1.00 15.06  ? 107 TYR Q CZ  1 
ATOM   4926 O OH  . TYR C 3 107 ? 141.926 145.146 101.257 1.00 23.89  ? 107 TYR Q OH  1 
ATOM   4927 N N   . TYR C 3 108 ? 147.859 145.886 107.360 1.00 12.79  ? 108 TYR Q N   1 
ATOM   4928 C CA  . TYR C 3 108 ? 148.890 145.826 108.380 1.00 4.78   ? 108 TYR Q CA  1 
ATOM   4929 C C   . TYR C 3 108 ? 148.643 144.643 109.300 1.00 7.33   ? 108 TYR Q C   1 
ATOM   4930 O O   . TYR C 3 108 ? 147.499 144.295 109.599 1.00 20.20  ? 108 TYR Q O   1 
ATOM   4931 C CB  . TYR C 3 108 ? 148.926 147.110 109.215 1.00 14.09  ? 108 TYR Q CB  1 
ATOM   4932 C CG  . TYR C 3 108 ? 149.416 148.327 108.471 1.00 13.13  ? 108 TYR Q CG  1 
ATOM   4933 C CD1 . TYR C 3 108 ? 150.769 148.584 108.338 1.00 14.43  ? 108 TYR Q CD1 1 
ATOM   4934 C CD2 . TYR C 3 108 ? 148.521 149.225 107.910 1.00 8.36   ? 108 TYR Q CD2 1 
ATOM   4935 C CE1 . TYR C 3 108 ? 151.216 149.695 107.663 1.00 14.78  ? 108 TYR Q CE1 1 
ATOM   4936 C CE2 . TYR C 3 108 ? 148.960 150.335 107.232 1.00 4.97   ? 108 TYR Q CE2 1 
ATOM   4937 C CZ  . TYR C 3 108 ? 150.309 150.566 107.112 1.00 10.85  ? 108 TYR Q CZ  1 
ATOM   4938 O OH  . TYR C 3 108 ? 150.755 151.677 106.437 1.00 24.13  ? 108 TYR Q OH  1 
ATOM   4939 N N   . CYS C 3 109 ? 149.730 144.030 109.751 1.00 10.24  ? 109 CYS Q N   1 
ATOM   4940 C CA  . CYS C 3 109 ? 149.687 142.972 110.746 1.00 14.52  ? 109 CYS Q CA  1 
ATOM   4941 C C   . CYS C 3 109 ? 150.297 143.482 112.042 1.00 24.52  ? 109 CYS Q C   1 
ATOM   4942 O O   . CYS C 3 109 ? 151.304 144.195 112.027 1.00 16.79  ? 109 CYS Q O   1 
ATOM   4943 C CB  . CYS C 3 109 ? 150.439 141.728 110.271 1.00 16.80  ? 109 CYS Q CB  1 
ATOM   4944 S SG  . CYS C 3 109 ? 152.158 142.035 109.856 1.00 37.54  ? 109 CYS Q SG  1 
ATOM   4945 N N   . GLN C 3 110 ? 149.682 143.123 113.160 1.00 14.87  ? 110 GLN Q N   1 
ATOM   4946 C CA  . GLN C 3 110 ? 150.146 143.545 114.468 1.00 0.00   ? 110 GLN Q CA  1 
ATOM   4947 C C   . GLN C 3 110 ? 150.277 142.336 115.380 1.00 4.82   ? 110 GLN Q C   1 
ATOM   4948 O O   . GLN C 3 110 ? 149.431 141.443 115.361 1.00 16.71  ? 110 GLN Q O   1 
ATOM   4949 C CB  . GLN C 3 110 ? 149.186 144.567 115.081 1.00 3.34   ? 110 GLN Q CB  1 
ATOM   4950 C CG  . GLN C 3 110 ? 149.542 145.002 116.481 1.00 0.00   ? 110 GLN Q CG  1 
ATOM   4951 C CD  . GLN C 3 110 ? 148.325 145.297 117.315 1.00 0.00   ? 110 GLN Q CD  1 
ATOM   4952 O OE1 . GLN C 3 110 ? 147.201 145.019 116.912 1.00 5.43   ? 110 GLN Q OE1 1 
ATOM   4953 N NE2 . GLN C 3 110 ? 148.541 145.859 118.491 1.00 7.82   ? 110 GLN Q NE2 1 
ATOM   4954 N N   . GLN C 3 111 ? 151.346 142.311 116.169 1.00 18.97  ? 111 GLN Q N   1 
ATOM   4955 C CA  . GLN C 3 111 ? 151.489 141.366 117.266 1.00 2.86   ? 111 GLN Q CA  1 
ATOM   4956 C C   . GLN C 3 111 ? 151.206 142.084 118.576 1.00 10.90  ? 111 GLN Q C   1 
ATOM   4957 O O   . GLN C 3 111 ? 151.604 143.236 118.763 1.00 25.23  ? 111 GLN Q O   1 
ATOM   4958 C CB  . GLN C 3 111 ? 152.891 140.751 117.300 1.00 1.30   ? 111 GLN Q CB  1 
ATOM   4959 C CG  . GLN C 3 111 ? 154.016 141.721 117.619 1.00 9.23   ? 111 GLN Q CG  1 
ATOM   4960 C CD  . GLN C 3 111 ? 154.431 141.683 119.074 1.00 19.86  ? 111 GLN Q CD  1 
ATOM   4961 O OE1 . GLN C 3 111 ? 153.967 140.846 119.840 1.00 19.92  ? 111 GLN Q OE1 1 
ATOM   4962 N NE2 . GLN C 3 111 ? 155.308 142.594 119.462 1.00 12.78  ? 111 GLN Q NE2 1 
ATOM   4963 N N   . TYR C 3 112 ? 150.499 141.410 119.477 1.00 3.28   ? 112 TYR Q N   1 
ATOM   4964 C CA  . TYR C 3 112 ? 150.214 141.993 120.779 1.00 4.90   ? 112 TYR Q CA  1 
ATOM   4965 C C   . TYR C 3 112 ? 150.441 140.977 121.884 1.00 12.88  ? 112 TYR Q C   1 
ATOM   4966 O O   . TYR C 3 112 ? 149.672 140.896 122.845 1.00 23.10  ? 112 TYR Q O   1 
ATOM   4967 C CB  . TYR C 3 112 ? 148.798 142.555 120.843 1.00 5.89   ? 112 TYR Q CB  1 
ATOM   4968 C CG  . TYR C 3 112 ? 147.707 141.627 120.376 1.00 0.18   ? 112 TYR Q CG  1 
ATOM   4969 C CD1 . TYR C 3 112 ? 147.063 140.782 121.267 1.00 4.83   ? 112 TYR Q CD1 1 
ATOM   4970 C CD2 . TYR C 3 112 ? 147.287 141.625 119.058 1.00 0.00   ? 112 TYR Q CD2 1 
ATOM   4971 C CE1 . TYR C 3 112 ? 146.053 139.949 120.855 1.00 0.00   ? 112 TYR Q CE1 1 
ATOM   4972 C CE2 . TYR C 3 112 ? 146.275 140.793 118.640 1.00 0.00   ? 112 TYR Q CE2 1 
ATOM   4973 C CZ  . TYR C 3 112 ? 145.662 139.958 119.543 1.00 0.87   ? 112 TYR Q CZ  1 
ATOM   4974 O OH  . TYR C 3 112 ? 144.653 139.124 119.138 1.00 9.07   ? 112 TYR Q OH  1 
ATOM   4975 N N   . LYS C 3 113 ? 151.505 140.189 121.766 1.00 9.13   ? 113 LYS Q N   1 
ATOM   4976 C CA  . LYS C 3 113 ? 151.930 139.329 122.857 1.00 18.83  ? 113 LYS Q CA  1 
ATOM   4977 C C   . LYS C 3 113 ? 152.912 140.014 123.794 1.00 15.21  ? 113 LYS Q C   1 
ATOM   4978 O O   . LYS C 3 113 ? 153.156 139.506 124.892 1.00 22.04  ? 113 LYS Q O   1 
ATOM   4979 C CB  . LYS C 3 113 ? 152.562 138.046 122.306 1.00 17.89  ? 113 LYS Q CB  1 
ATOM   4980 C CG  . LYS C 3 113 ? 152.483 136.858 123.245 1.00 12.01  ? 113 LYS Q CG  1 
ATOM   4981 C CD  . LYS C 3 113 ? 153.679 135.947 123.070 1.00 23.81  ? 113 LYS Q CD  1 
ATOM   4982 C CE  . LYS C 3 113 ? 153.929 135.114 124.313 1.00 29.41  ? 113 LYS Q CE  1 
ATOM   4983 N NZ  . LYS C 3 113 ? 155.159 134.283 124.182 1.00 25.33  ? 113 LYS Q NZ  1 
ATOM   4984 N N   . TYR C 3 114 ? 153.465 141.155 123.394 1.00 23.21  ? 114 TYR Q N   1 
ATOM   4985 C CA  . TYR C 3 114 ? 154.427 141.892 124.196 1.00 25.09  ? 114 TYR Q CA  1 
ATOM   4986 C C   . TYR C 3 114 ? 154.087 143.374 124.160 1.00 21.86  ? 114 TYR Q C   1 
ATOM   4987 O O   . TYR C 3 114 ? 153.394 143.849 123.258 1.00 22.09  ? 114 TYR Q O   1 
ATOM   4988 C CB  . TYR C 3 114 ? 155.857 141.642 123.707 1.00 21.52  ? 114 TYR Q CB  1 
ATOM   4989 C CG  . TYR C 3 114 ? 156.235 140.180 123.736 1.00 16.56  ? 114 TYR Q CG  1 
ATOM   4990 C CD1 . TYR C 3 114 ? 156.623 139.570 124.919 1.00 25.06  ? 114 TYR Q CD1 1 
ATOM   4991 C CD2 . TYR C 3 114 ? 156.178 139.404 122.592 1.00 23.83  ? 114 TYR Q CD2 1 
ATOM   4992 C CE1 . TYR C 3 114 ? 156.960 138.234 124.956 1.00 24.90  ? 114 TYR Q CE1 1 
ATOM   4993 C CE2 . TYR C 3 114 ? 156.513 138.067 122.620 1.00 23.50  ? 114 TYR Q CE2 1 
ATOM   4994 C CZ  . TYR C 3 114 ? 156.903 137.488 123.803 1.00 29.81  ? 114 TYR Q CZ  1 
ATOM   4995 O OH  . TYR C 3 114 ? 157.237 136.155 123.831 1.00 29.39  ? 114 TYR Q OH  1 
ATOM   4996 N N   . VAL C 3 115 ? 154.573 144.101 125.173 1.00 22.59  ? 115 VAL Q N   1 
ATOM   4997 C CA  . VAL C 3 115 ? 154.184 145.506 125.331 1.00 24.65  ? 115 VAL Q CA  1 
ATOM   4998 C C   . VAL C 3 115 ? 154.569 146.351 124.127 1.00 32.56  ? 115 VAL Q C   1 
ATOM   4999 O O   . VAL C 3 115 ? 153.731 147.139 123.660 1.00 32.20  ? 115 VAL Q O   1 
ATOM   5000 C CB  . VAL C 3 115 ? 154.719 146.059 126.658 1.00 23.35  ? 115 VAL Q CB  1 
ATOM   5001 C CG1 . VAL C 3 115 ? 154.426 147.542 126.772 1.00 26.18  ? 115 VAL Q CG1 1 
ATOM   5002 C CG2 . VAL C 3 115 ? 154.091 145.313 127.817 1.00 31.35  ? 115 VAL Q CG2 1 
ATOM   5003 N N   . PRO C 3 116 ? 155.783 146.258 123.566 1.00 27.93  ? 116 PRO Q N   1 
ATOM   5004 C CA  . PRO C 3 116 ? 156.036 146.965 122.307 1.00 10.11  ? 116 PRO Q CA  1 
ATOM   5005 C C   . PRO C 3 116 ? 155.277 146.322 121.161 1.00 23.11  ? 116 PRO Q C   1 
ATOM   5006 O O   . PRO C 3 116 ? 155.877 145.605 120.356 1.00 36.53  ? 116 PRO Q O   1 
ATOM   5007 C CB  . PRO C 3 116 ? 157.553 146.829 122.118 1.00 10.80  ? 116 PRO Q CB  1 
ATOM   5008 C CG  . PRO C 3 116 ? 158.079 146.461 123.457 1.00 29.93  ? 116 PRO Q CG  1 
ATOM   5009 C CD  . PRO C 3 116 ? 157.012 145.631 124.080 1.00 23.45  ? 116 PRO Q CD  1 
ATOM   5010 N N   . VAL C 3 117 ? 153.963 146.549 121.082 1.00 16.84  ? 117 VAL Q N   1 
ATOM   5011 C CA  . VAL C 3 117 ? 153.183 145.953 120.007 1.00 5.04   ? 117 VAL Q CA  1 
ATOM   5012 C C   . VAL C 3 117 ? 153.685 146.488 118.675 1.00 13.50  ? 117 VAL Q C   1 
ATOM   5013 O O   . VAL C 3 117 ? 153.793 147.703 118.469 1.00 22.43  ? 117 VAL Q O   1 
ATOM   5014 C CB  . VAL C 3 117 ? 151.682 146.214 120.210 1.00 0.00   ? 117 VAL Q CB  1 
ATOM   5015 C CG1 . VAL C 3 117 ? 151.189 145.494 121.446 1.00 11.79  ? 117 VAL Q CG1 1 
ATOM   5016 C CG2 . VAL C 3 117 ? 151.391 147.689 120.321 1.00 12.76  ? 117 VAL Q CG2 1 
ATOM   5017 N N   . THR C 3 118 ? 154.018 145.576 117.770 1.00 11.40  ? 118 THR Q N   1 
ATOM   5018 C CA  . THR C 3 118 ? 154.725 145.908 116.544 1.00 14.78  ? 118 THR Q CA  1 
ATOM   5019 C C   . THR C 3 118 ? 153.801 145.709 115.357 1.00 17.10  ? 118 THR Q C   1 
ATOM   5020 O O   . THR C 3 118 ? 153.025 144.751 115.323 1.00 17.14  ? 118 THR Q O   1 
ATOM   5021 C CB  . THR C 3 118 ? 155.981 145.054 116.380 1.00 18.87  ? 118 THR Q CB  1 
ATOM   5022 O OG1 . THR C 3 118 ? 156.558 144.804 117.664 1.00 20.91  ? 118 THR Q OG1 1 
ATOM   5023 C CG2 . THR C 3 118 ? 156.996 145.779 115.521 1.00 23.82  ? 118 THR Q CG2 1 
ATOM   5024 N N   . PHE C 3 119 ? 153.885 146.620 114.395 1.00 12.30  ? 119 PHE Q N   1 
ATOM   5025 C CA  . PHE C 3 119 ? 153.099 146.562 113.176 1.00 12.86  ? 119 PHE Q CA  1 
ATOM   5026 C C   . PHE C 3 119 ? 153.989 146.173 112.005 1.00 19.58  ? 119 PHE Q C   1 
ATOM   5027 O O   . PHE C 3 119 ? 155.205 146.376 112.033 1.00 30.52  ? 119 PHE Q O   1 
ATOM   5028 C CB  . PHE C 3 119 ? 152.426 147.906 112.891 1.00 11.34  ? 119 PHE Q CB  1 
ATOM   5029 C CG  . PHE C 3 119 ? 151.254 148.200 113.779 1.00 0.00   ? 119 PHE Q CG  1 
ATOM   5030 C CD1 . PHE C 3 119 ? 149.982 147.809 113.415 1.00 1.43   ? 119 PHE Q CD1 1 
ATOM   5031 C CD2 . PHE C 3 119 ? 151.426 148.870 114.973 1.00 0.00   ? 119 PHE Q CD2 1 
ATOM   5032 C CE1 . PHE C 3 119 ? 148.906 148.084 114.224 1.00 0.97   ? 119 PHE Q CE1 1 
ATOM   5033 C CE2 . PHE C 3 119 ? 150.356 149.144 115.785 1.00 0.55   ? 119 PHE Q CE2 1 
ATOM   5034 C CZ  . PHE C 3 119 ? 149.094 148.750 115.411 1.00 0.00   ? 119 PHE Q CZ  1 
ATOM   5035 N N   . GLY C 3 120 ? 153.374 145.596 110.979 1.00 13.21  ? 120 GLY Q N   1 
ATOM   5036 C CA  . GLY C 3 120 ? 154.088 145.323 109.753 1.00 8.65   ? 120 GLY Q CA  1 
ATOM   5037 C C   . GLY C 3 120 ? 154.296 146.576 108.929 1.00 18.53  ? 120 GLY Q C   1 
ATOM   5038 O O   . GLY C 3 120 ? 153.749 147.641 109.209 1.00 37.59  ? 120 GLY Q O   1 
ATOM   5039 N N   . GLN C 3 121 ? 155.115 146.444 107.888 1.00 8.31   ? 121 GLN Q N   1 
ATOM   5040 C CA  . GLN C 3 121 ? 155.382 147.581 107.020 1.00 10.18  ? 121 GLN Q CA  1 
ATOM   5041 C C   . GLN C 3 121 ? 154.211 147.917 106.109 1.00 17.20  ? 121 GLN Q C   1 
ATOM   5042 O O   . GLN C 3 121 ? 154.186 149.016 105.548 1.00 22.12  ? 121 GLN Q O   1 
ATOM   5043 C CB  . GLN C 3 121 ? 156.631 147.321 106.182 1.00 18.41  ? 121 GLN Q CB  1 
ATOM   5044 C CG  . GLN C 3 121 ? 157.903 147.211 106.996 1.00 28.33  ? 121 GLN Q CG  1 
ATOM   5045 C CD  . GLN C 3 121 ? 158.127 145.813 107.538 1.00 34.39  ? 121 GLN Q CD  1 
ATOM   5046 O OE1 . GLN C 3 121 ? 157.326 144.908 107.307 1.00 34.51  ? 121 GLN Q OE1 1 
ATOM   5047 N NE2 . GLN C 3 121 ? 159.220 145.633 108.269 1.00 28.21  ? 121 GLN Q NE2 1 
ATOM   5048 N N   . GLY C 3 122 ? 153.256 147.018 105.950 1.00 15.81  ? 122 GLY Q N   1 
ATOM   5049 C CA  . GLY C 3 122 ? 152.082 147.282 105.143 1.00 12.53  ? 122 GLY Q CA  1 
ATOM   5050 C C   . GLY C 3 122 ? 152.182 146.672 103.758 1.00 18.54  ? 122 GLY Q C   1 
ATOM   5051 O O   . GLY C 3 122 ? 153.263 146.559 103.170 1.00 27.28  ? 122 GLY Q O   1 
ATOM   5052 N N   . THR C 3 123 ? 151.033 146.265 103.225 1.00 23.71  ? 123 THR Q N   1 
ATOM   5053 C CA  . THR C 3 123 ? 150.937 145.694 101.888 1.00 20.78  ? 123 THR Q CA  1 
ATOM   5054 C C   . THR C 3 123 ? 149.850 146.436 101.128 1.00 25.18  ? 123 THR Q C   1 
ATOM   5055 O O   . THR C 3 123 ? 148.686 146.422 101.537 1.00 25.45  ? 123 THR Q O   1 
ATOM   5056 C CB  . THR C 3 123 ? 150.626 144.194 101.939 1.00 22.59  ? 123 THR Q CB  1 
ATOM   5057 O OG1 . THR C 3 123 ? 151.807 143.472 102.301 1.00 36.53  ? 123 THR Q OG1 1 
ATOM   5058 C CG2 . THR C 3 123 ? 150.151 143.700 100.588 1.00 26.84  ? 123 THR Q CG2 1 
ATOM   5059 N N   . LYS C 3 124 ? 150.228 147.078 100.027 1.00 19.62  ? 124 LYS Q N   1 
ATOM   5060 C CA  . LYS C 3 124 ? 149.293 147.839 99.209  1.00 16.24  ? 124 LYS Q CA  1 
ATOM   5061 C C   . LYS C 3 124 ? 148.755 146.933 98.110  1.00 26.72  ? 124 LYS Q C   1 
ATOM   5062 O O   . LYS C 3 124 ? 149.503 146.510 97.224  1.00 41.35  ? 124 LYS Q O   1 
ATOM   5063 C CB  . LYS C 3 124 ? 149.974 149.071 98.622  1.00 25.03  ? 124 LYS Q CB  1 
ATOM   5064 C CG  . LYS C 3 124 ? 149.055 149.953 97.804  1.00 27.52  ? 124 LYS Q CG  1 
ATOM   5065 C CD  . LYS C 3 124 ? 149.246 151.415 98.147  1.00 24.27  ? 124 LYS Q CD  1 
ATOM   5066 C CE  . LYS C 3 124 ? 148.319 152.296 97.332  1.00 28.40  ? 124 LYS Q CE  1 
ATOM   5067 N NZ  . LYS C 3 124 ? 148.857 152.576 95.975  1.00 30.92  ? 124 LYS Q NZ  1 
ATOM   5068 N N   . VAL C 3 125 ? 147.462 146.639 98.165  1.00 26.48  ? 125 VAL Q N   1 
ATOM   5069 C CA  . VAL C 3 125 ? 146.800 145.785 97.187  1.00 26.09  ? 125 VAL Q CA  1 
ATOM   5070 C C   . VAL C 3 125 ? 146.174 146.704 96.146  1.00 37.50  ? 125 VAL Q C   1 
ATOM   5071 O O   . VAL C 3 125 ? 145.091 147.255 96.354  1.00 40.58  ? 125 VAL Q O   1 
ATOM   5072 C CB  . VAL C 3 125 ? 145.762 144.873 97.842  1.00 25.69  ? 125 VAL Q CB  1 
ATOM   5073 C CG1 . VAL C 3 125 ? 145.089 144.008 96.798  1.00 33.13  ? 125 VAL Q CG1 1 
ATOM   5074 C CG2 . VAL C 3 125 ? 146.421 144.016 98.902  1.00 26.74  ? 125 VAL Q CG2 1 
ATOM   5075 N N   . GLU C 3 126 ? 146.860 146.874 95.021  1.00 50.72  ? 126 GLU Q N   1 
ATOM   5076 C CA  . GLU C 3 126 ? 146.402 147.745 93.952  1.00 45.47  ? 126 GLU Q CA  1 
ATOM   5077 C C   . GLU C 3 126 ? 145.690 146.940 92.875  1.00 47.75  ? 126 GLU Q C   1 
ATOM   5078 O O   . GLU C 3 126 ? 145.998 145.769 92.641  1.00 54.22  ? 126 GLU Q O   1 
ATOM   5079 C CB  . GLU C 3 126 ? 147.575 148.505 93.335  1.00 44.48  ? 126 GLU Q CB  1 
ATOM   5080 C CG  . GLU C 3 126 ? 148.588 148.996 94.348  1.00 48.63  ? 126 GLU Q CG  1 
ATOM   5081 C CD  . GLU C 3 126 ? 150.011 148.902 93.841  1.00 52.56  ? 126 GLU Q CD  1 
ATOM   5082 O OE1 . GLU C 3 126 ? 150.218 148.318 92.758  1.00 54.16  ? 126 GLU Q OE1 1 
ATOM   5083 O OE2 . GLU C 3 126 ? 150.923 149.413 94.525  1.00 51.73  ? 126 GLU Q OE2 1 
ATOM   5084 N N   . ILE C 3 127 ? 144.733 147.583 92.217  1.00 58.58  ? 127 ILE Q N   1 
ATOM   5085 C CA  . ILE C 3 127 ? 143.982 146.942 91.144  1.00 63.40  ? 127 ILE Q CA  1 
ATOM   5086 C C   . ILE C 3 127 ? 144.808 147.004 89.866  1.00 61.45  ? 127 ILE Q C   1 
ATOM   5087 O O   . ILE C 3 127 ? 145.289 148.074 89.475  1.00 63.83  ? 127 ILE Q O   1 
ATOM   5088 C CB  . ILE C 3 127 ? 142.606 147.608 90.964  1.00 62.91  ? 127 ILE Q CB  1 
ATOM   5089 C CG1 . ILE C 3 127 ? 141.546 146.963 91.872  1.00 65.34  ? 127 ILE Q CG1 1 
ATOM   5090 C CG2 . ILE C 3 127 ? 142.154 147.532 89.514  1.00 59.87  ? 127 ILE Q CG2 1 
ATOM   5091 C CD1 . ILE C 3 127 ? 141.980 146.668 93.302  1.00 59.07  ? 127 ILE Q CD1 1 
ATOM   5092 N N   . LYS C 3 128 ? 144.985 145.856 89.221  1.00 66.55  ? 128 LYS Q N   1 
ATOM   5093 C CA  . LYS C 3 128 ? 145.836 145.740 88.047  1.00 70.24  ? 128 LYS Q CA  1 
ATOM   5094 C C   . LYS C 3 128 ? 144.998 145.651 86.779  1.00 69.98  ? 128 LYS Q C   1 
ATOM   5095 O O   . LYS C 3 128 ? 143.866 145.161 86.792  1.00 72.17  ? 128 LYS Q O   1 
ATOM   5096 C CB  . LYS C 3 128 ? 146.743 144.513 88.153  1.00 67.15  ? 128 LYS Q CB  1 
ATOM   5097 N N   . ARG C 3 129 ? 145.568 146.132 85.681  1.00 85.21  ? 129 ARG Q N   1 
ATOM   5098 C CA  . ARG C 3 129 ? 144.901 146.108 84.385  1.00 87.61  ? 129 ARG Q CA  1 
ATOM   5099 C C   . ARG C 3 129 ? 145.975 146.121 83.300  1.00 88.84  ? 129 ARG Q C   1 
ATOM   5100 O O   . ARG C 3 129 ? 147.160 145.910 83.581  1.00 87.66  ? 129 ARG Q O   1 
ATOM   5101 C CB  . ARG C 3 129 ? 143.906 147.276 84.269  1.00 87.57  ? 129 ARG Q CB  1 
ATOM   5102 N N   . THR C 3 130 ? 145.561 146.367 82.059  1.00 100.80 ? 130 THR Q N   1 
ATOM   5103 C CA  . THR C 3 130 ? 146.466 146.267 80.922  1.00 101.33 ? 130 THR Q CA  1 
ATOM   5104 C C   . THR C 3 130 ? 147.569 147.316 80.993  1.00 102.35 ? 130 THR Q C   1 
ATOM   5105 O O   . THR C 3 130 ? 147.330 148.473 81.352  1.00 102.29 ? 130 THR Q O   1 
ATOM   5106 C CB  . THR C 3 130 ? 145.691 146.423 79.615  1.00 101.51 ? 130 THR Q CB  1 
ATOM   5107 O OG1 . THR C 3 130 ? 144.951 147.650 79.643  1.00 101.73 ? 130 THR Q OG1 1 
ATOM   5108 C CG2 . THR C 3 130 ? 144.728 145.261 79.425  1.00 100.81 ? 130 THR Q CG2 1 
ATOM   5109 N N   . VAL C 3 131 ? 148.785 146.902 80.633  1.00 103.70 ? 131 VAL Q N   1 
ATOM   5110 C CA  . VAL C 3 131 ? 149.924 147.812 80.620  1.00 103.88 ? 131 VAL Q CA  1 
ATOM   5111 C C   . VAL C 3 131 ? 149.750 148.833 79.505  1.00 103.22 ? 131 VAL Q C   1 
ATOM   5112 O O   . VAL C 3 131 ? 149.288 148.507 78.403  1.00 101.47 ? 131 VAL Q O   1 
ATOM   5113 C CB  . VAL C 3 131 ? 151.234 147.023 80.457  1.00 102.82 ? 131 VAL Q CB  1 
ATOM   5114 C CG1 . VAL C 3 131 ? 152.435 147.946 80.574  1.00 103.19 ? 131 VAL Q CG1 1 
ATOM   5115 C CG2 . VAL C 3 131 ? 151.313 145.910 81.487  1.00 103.80 ? 131 VAL Q CG2 1 
ATOM   5116 N N   . ALA C 3 132 ? 150.117 150.081 79.787  1.00 110.95 ? 132 ALA Q N   1 
ATOM   5117 C CA  . ALA C 3 132 ? 149.974 151.173 78.837  1.00 111.42 ? 132 ALA Q CA  1 
ATOM   5118 C C   . ALA C 3 132 ? 151.313 151.869 78.641  1.00 111.01 ? 132 ALA Q C   1 
ATOM   5119 O O   . ALA C 3 132 ? 152.155 151.901 79.542  1.00 109.09 ? 132 ALA Q O   1 
ATOM   5120 C CB  . ALA C 3 132 ? 148.917 152.187 79.298  1.00 110.12 ? 132 ALA Q CB  1 
ATOM   5121 N N   . ALA C 3 133 ? 151.496 152.425 77.450  1.00 109.56 ? 133 ALA Q N   1 
ATOM   5122 C CA  . ALA C 3 133 ? 152.738 153.109 77.111  1.00 109.05 ? 133 ALA Q CA  1 
ATOM   5123 C C   . ALA C 3 133 ? 152.775 154.485 77.768  1.00 110.25 ? 133 ALA Q C   1 
ATOM   5124 O O   . ALA C 3 133 ? 151.831 155.266 77.611  1.00 110.31 ? 133 ALA Q O   1 
ATOM   5125 C CB  . ALA C 3 133 ? 152.879 153.249 75.600  1.00 107.74 ? 133 ALA Q CB  1 
ATOM   5126 N N   . PRO C 3 134 ? 153.831 154.811 78.509  1.00 112.77 ? 134 PRO Q N   1 
ATOM   5127 C CA  . PRO C 3 134 ? 153.928 156.144 79.110  1.00 111.61 ? 134 PRO Q CA  1 
ATOM   5128 C C   . PRO C 3 134 ? 154.234 157.207 78.067  1.00 111.85 ? 134 PRO Q C   1 
ATOM   5129 O O   . PRO C 3 134 ? 154.753 156.933 76.984  1.00 112.01 ? 134 PRO Q O   1 
ATOM   5130 C CB  . PRO C 3 134 ? 155.083 155.999 80.104  1.00 110.01 ? 134 PRO Q CB  1 
ATOM   5131 C CG  . PRO C 3 134 ? 155.934 154.937 79.511  1.00 110.77 ? 134 PRO Q CG  1 
ATOM   5132 C CD  . PRO C 3 134 ? 154.995 153.972 78.836  1.00 111.60 ? 134 PRO Q CD  1 
ATOM   5133 N N   . SER C 3 135 ? 153.901 158.446 78.418  1.00 113.18 ? 135 SER Q N   1 
ATOM   5134 C CA  . SER C 3 135 ? 154.177 159.608 77.585  1.00 113.28 ? 135 SER Q CA  1 
ATOM   5135 C C   . SER C 3 135 ? 155.078 160.561 78.354  1.00 112.56 ? 135 SER Q C   1 
ATOM   5136 O O   . SER C 3 135 ? 154.826 160.846 79.529  1.00 112.55 ? 135 SER Q O   1 
ATOM   5137 C CB  . SER C 3 135 ? 152.882 160.307 77.168  1.00 114.15 ? 135 SER Q CB  1 
ATOM   5138 O OG  . SER C 3 135 ? 153.082 161.099 76.010  1.00 114.20 ? 135 SER Q OG  1 
ATOM   5139 N N   . VAL C 3 136 ? 156.123 161.052 77.693  1.00 115.71 ? 136 VAL Q N   1 
ATOM   5140 C CA  . VAL C 3 136 ? 157.147 161.877 78.324  1.00 116.67 ? 136 VAL Q CA  1 
ATOM   5141 C C   . VAL C 3 136 ? 157.088 163.273 77.722  1.00 116.75 ? 136 VAL Q C   1 
ATOM   5142 O O   . VAL C 3 136 ? 157.083 163.425 76.495  1.00 117.80 ? 136 VAL Q O   1 
ATOM   5143 C CB  . VAL C 3 136 ? 158.548 161.266 78.151  1.00 116.66 ? 136 VAL Q CB  1 
ATOM   5144 C CG1 . VAL C 3 136 ? 159.522 161.885 79.136  1.00 115.54 ? 136 VAL Q CG1 1 
ATOM   5145 C CG2 . VAL C 3 136 ? 158.492 159.758 78.326  1.00 115.25 ? 136 VAL Q CG2 1 
ATOM   5146 N N   . PHE C 3 137 ? 157.041 164.287 78.585  1.00 113.42 ? 137 PHE Q N   1 
ATOM   5147 C CA  . PHE C 3 137 ? 156.986 165.679 78.161  1.00 113.06 ? 137 PHE Q CA  1 
ATOM   5148 C C   . PHE C 3 137 ? 158.106 166.457 78.838  1.00 114.51 ? 137 PHE Q C   1 
ATOM   5149 O O   . PHE C 3 137 ? 158.659 166.035 79.856  1.00 114.69 ? 137 PHE Q O   1 
ATOM   5150 C CB  . PHE C 3 137 ? 155.636 166.357 78.480  1.00 112.33 ? 137 PHE Q CB  1 
ATOM   5151 C CG  . PHE C 3 137 ? 154.426 165.650 77.916  1.00 113.34 ? 137 PHE Q CG  1 
ATOM   5152 C CD1 . PHE C 3 137 ? 154.111 164.350 78.277  1.00 113.37 ? 137 PHE Q CD1 1 
ATOM   5153 C CD2 . PHE C 3 137 ? 153.613 166.294 76.999  1.00 114.35 ? 137 PHE Q CD2 1 
ATOM   5154 C CE1 . PHE C 3 137 ? 153.004 163.718 77.751  1.00 113.61 ? 137 PHE Q CE1 1 
ATOM   5155 C CE2 . PHE C 3 137 ? 152.504 165.666 76.468  1.00 114.45 ? 137 PHE Q CE2 1 
ATOM   5156 C CZ  . PHE C 3 137 ? 152.200 164.377 76.843  1.00 113.70 ? 137 PHE Q CZ  1 
ATOM   5157 N N   . ILE C 3 138 ? 158.439 167.605 78.251  1.00 121.95 ? 138 ILE Q N   1 
ATOM   5158 C CA  . ILE C 3 138 ? 159.464 168.500 78.775  1.00 122.35 ? 138 ILE Q CA  1 
ATOM   5159 C C   . ILE C 3 138 ? 158.890 169.907 78.853  1.00 121.99 ? 138 ILE Q C   1 
ATOM   5160 O O   . ILE C 3 138 ? 158.302 170.398 77.883  1.00 121.06 ? 138 ILE Q O   1 
ATOM   5161 C CB  . ILE C 3 138 ? 160.738 168.482 77.909  1.00 122.03 ? 138 ILE Q CB  1 
ATOM   5162 C CG1 . ILE C 3 138 ? 161.497 167.174 78.119  1.00 122.26 ? 138 ILE Q CG1 1 
ATOM   5163 C CG2 . ILE C 3 138 ? 161.630 169.670 78.234  1.00 121.96 ? 138 ILE Q CG2 1 
ATOM   5164 C CD1 . ILE C 3 138 ? 161.940 166.967 79.546  1.00 120.49 ? 138 ILE Q CD1 1 
ATOM   5165 N N   . PHE C 3 139 ? 159.057 170.552 80.007  1.00 116.04 ? 139 PHE Q N   1 
ATOM   5166 C CA  . PHE C 3 139 ? 158.608 171.925 80.214  1.00 116.15 ? 139 PHE Q CA  1 
ATOM   5167 C C   . PHE C 3 139 ? 159.792 172.752 80.696  1.00 116.28 ? 139 PHE Q C   1 
ATOM   5168 O O   . PHE C 3 139 ? 160.308 172.502 81.805  1.00 115.44 ? 139 PHE Q O   1 
ATOM   5169 C CB  . PHE C 3 139 ? 157.454 171.993 81.216  1.00 116.14 ? 139 PHE Q CB  1 
ATOM   5170 C CG  . PHE C 3 139 ? 156.461 170.881 81.073  1.00 114.70 ? 139 PHE Q CG  1 
ATOM   5171 C CD1 . PHE C 3 139 ? 156.656 169.672 81.715  1.00 115.09 ? 139 PHE Q CD1 1 
ATOM   5172 C CD2 . PHE C 3 139 ? 155.319 171.053 80.313  1.00 114.83 ? 139 PHE Q CD2 1 
ATOM   5173 C CE1 . PHE C 3 139 ? 155.742 168.653 81.589  1.00 116.26 ? 139 PHE Q CE1 1 
ATOM   5174 C CE2 . PHE C 3 139 ? 154.400 170.034 80.182  1.00 115.24 ? 139 PHE Q CE2 1 
ATOM   5175 C CZ  . PHE C 3 139 ? 154.613 168.833 80.822  1.00 116.29 ? 139 PHE Q CZ  1 
ATOM   5176 N N   . PRO C 3 140 ? 160.260 173.729 79.917  1.00 118.71 ? 140 PRO Q N   1 
ATOM   5177 C CA  . PRO C 3 140 ? 161.379 174.548 80.374  1.00 118.47 ? 140 PRO Q CA  1 
ATOM   5178 C C   . PRO C 3 140 ? 160.957 175.440 81.526  1.00 119.63 ? 140 PRO Q C   1 
ATOM   5179 O O   . PRO C 3 140 ? 159.770 175.788 81.658  1.00 120.53 ? 140 PRO Q O   1 
ATOM   5180 C CB  . PRO C 3 140 ? 161.750 175.374 79.128  1.00 118.41 ? 140 PRO Q CB  1 
ATOM   5181 C CG  . PRO C 3 140 ? 160.921 174.831 77.998  1.00 117.83 ? 140 PRO Q CG  1 
ATOM   5182 C CD  . PRO C 3 140 ? 159.743 174.163 78.611  1.00 118.43 ? 140 PRO Q CD  1 
ATOM   5183 N N   . PRO C 3 141 ? 161.891 175.828 82.395  1.00 122.46 ? 141 PRO Q N   1 
ATOM   5184 C CA  . PRO C 3 141 ? 161.538 176.721 83.505  1.00 122.38 ? 141 PRO Q CA  1 
ATOM   5185 C C   . PRO C 3 141 ? 161.045 178.070 83.003  1.00 123.06 ? 141 PRO Q C   1 
ATOM   5186 O O   . PRO C 3 141 ? 161.478 178.569 81.962  1.00 123.39 ? 141 PRO Q O   1 
ATOM   5187 C CB  . PRO C 3 141 ? 162.852 176.860 84.283  1.00 121.35 ? 141 PRO Q CB  1 
ATOM   5188 C CG  . PRO C 3 141 ? 163.920 176.488 83.307  1.00 121.94 ? 141 PRO Q CG  1 
ATOM   5189 C CD  . PRO C 3 141 ? 163.312 175.449 82.418  1.00 121.78 ? 141 PRO Q CD  1 
ATOM   5190 N N   . SER C 3 142 ? 160.123 178.657 83.760  1.00 122.35 ? 142 SER Q N   1 
ATOM   5191 C CA  . SER C 3 142 ? 159.557 179.945 83.390  1.00 123.15 ? 142 SER Q CA  1 
ATOM   5192 C C   . SER C 3 142 ? 160.618 181.038 83.440  1.00 123.31 ? 142 SER Q C   1 
ATOM   5193 O O   . SER C 3 142 ? 161.562 180.986 84.232  1.00 123.37 ? 142 SER Q O   1 
ATOM   5194 C CB  . SER C 3 142 ? 158.398 180.308 84.317  1.00 122.69 ? 142 SER Q CB  1 
ATOM   5195 O OG  . SER C 3 142 ? 157.299 179.436 84.130  1.00 121.77 ? 142 SER Q OG  1 
ATOM   5196 N N   . ASP C 3 143 ? 160.452 182.039 82.572  1.00 124.41 ? 143 ASP Q N   1 
ATOM   5197 C CA  . ASP C 3 143 ? 161.365 183.178 82.578  1.00 124.96 ? 143 ASP Q CA  1 
ATOM   5198 C C   . ASP C 3 143 ? 161.256 183.972 83.872  1.00 124.11 ? 143 ASP Q C   1 
ATOM   5199 O O   . ASP C 3 143 ? 162.248 184.548 84.332  1.00 122.55 ? 143 ASP Q O   1 
ATOM   5200 C CB  . ASP C 3 143 ? 161.091 184.076 81.372  1.00 124.33 ? 143 ASP Q CB  1 
ATOM   5201 C CG  . ASP C 3 143 ? 161.085 183.309 80.065  1.00 124.57 ? 143 ASP Q CG  1 
ATOM   5202 O OD1 . ASP C 3 143 ? 161.743 182.250 79.994  1.00 124.61 ? 143 ASP Q OD1 1 
ATOM   5203 O OD2 . ASP C 3 143 ? 160.424 183.766 79.109  1.00 124.76 ? 143 ASP Q OD2 1 
ATOM   5204 N N   . SER C 3 144 ? 160.063 184.018 84.470  1.00 122.49 ? 144 SER Q N   1 
ATOM   5205 C CA  . SER C 3 144 ? 159.917 184.653 85.775  1.00 122.07 ? 144 SER Q CA  1 
ATOM   5206 C C   . SER C 3 144 ? 160.705 183.908 86.842  1.00 122.08 ? 144 SER Q C   1 
ATOM   5207 O O   . SER C 3 144 ? 161.197 184.522 87.795  1.00 122.77 ? 144 SER Q O   1 
ATOM   5208 C CB  . SER C 3 144 ? 158.440 184.729 86.162  1.00 121.80 ? 144 SER Q CB  1 
ATOM   5209 O OG  . SER C 3 144 ? 157.675 185.339 85.138  1.00 121.41 ? 144 SER Q OG  1 
ATOM   5210 N N   . GLN C 3 145 ? 160.826 182.586 86.704  1.00 121.84 ? 145 GLN Q N   1 
ATOM   5211 C CA  . GLN C 3 145 ? 161.620 181.810 87.649  1.00 122.69 ? 145 GLN Q CA  1 
ATOM   5212 C C   . GLN C 3 145 ? 163.095 182.186 87.573  1.00 123.42 ? 145 GLN Q C   1 
ATOM   5213 O O   . GLN C 3 145 ? 163.772 182.273 88.603  1.00 123.53 ? 145 GLN Q O   1 
ATOM   5214 C CB  . GLN C 3 145 ? 161.427 180.317 87.386  1.00 122.45 ? 145 GLN Q CB  1 
ATOM   5215 C CG  . GLN C 3 145 ? 162.110 179.409 88.391  1.00 122.67 ? 145 GLN Q CG  1 
ATOM   5216 C CD  . GLN C 3 145 ? 161.521 178.012 88.407  1.00 123.25 ? 145 GLN Q CD  1 
ATOM   5217 O OE1 . GLN C 3 145 ? 160.479 177.759 87.803  1.00 123.86 ? 145 GLN Q OE1 1 
ATOM   5218 N NE2 . GLN C 3 145 ? 162.184 177.098 89.105  1.00 123.05 ? 145 GLN Q NE2 1 
ATOM   5219 N N   . LEU C 3 146 ? 163.607 182.417 86.360  1.00 124.08 ? 146 LEU Q N   1 
ATOM   5220 C CA  . LEU C 3 146 ? 165.015 182.768 86.202  1.00 124.43 ? 146 LEU Q CA  1 
ATOM   5221 C C   . LEU C 3 146 ? 165.338 184.088 86.892  1.00 125.03 ? 146 LEU Q C   1 
ATOM   5222 O O   . LEU C 3 146 ? 166.395 184.227 87.517  1.00 124.81 ? 146 LEU Q O   1 
ATOM   5223 C CB  . LEU C 3 146 ? 165.379 182.838 84.719  1.00 124.09 ? 146 LEU Q CB  1 
ATOM   5224 C CG  . LEU C 3 146 ? 164.687 181.843 83.787  1.00 124.12 ? 146 LEU Q CG  1 
ATOM   5225 C CD1 . LEU C 3 146 ? 164.940 182.208 82.334  1.00 123.44 ? 146 LEU Q CD1 1 
ATOM   5226 C CD2 . LEU C 3 146 ? 165.152 180.425 84.073  1.00 124.34 ? 146 LEU Q CD2 1 
ATOM   5227 N N   . LYS C 3 147 ? 164.440 185.069 86.786  1.00 128.70 ? 147 LYS Q N   1 
ATOM   5228 C CA  . LYS C 3 147 ? 164.662 186.358 87.430  1.00 128.36 ? 147 LYS Q CA  1 
ATOM   5229 C C   . LYS C 3 147 ? 164.636 186.262 88.949  1.00 128.52 ? 147 LYS Q C   1 
ATOM   5230 O O   . LYS C 3 147 ? 165.100 187.189 89.623  1.00 129.41 ? 147 LYS Q O   1 
ATOM   5231 C CB  . LYS C 3 147 ? 163.617 187.369 86.956  1.00 128.25 ? 147 LYS Q CB  1 
ATOM   5232 C CG  . LYS C 3 147 ? 163.733 187.736 85.486  1.00 128.37 ? 147 LYS Q CG  1 
ATOM   5233 C CD  . LYS C 3 147 ? 162.669 188.741 85.080  1.00 129.06 ? 147 LYS Q CD  1 
ATOM   5234 C CE  . LYS C 3 147 ? 162.867 189.201 83.645  1.00 128.65 ? 147 LYS Q CE  1 
ATOM   5235 N NZ  . LYS C 3 147 ? 161.866 190.227 83.244  1.00 128.74 ? 147 LYS Q NZ  1 
ATOM   5236 N N   . SER C 3 148 ? 164.110 185.172 89.502  1.00 127.93 ? 148 SER Q N   1 
ATOM   5237 C CA  . SER C 3 148 ? 164.067 184.973 90.944  1.00 128.80 ? 148 SER Q CA  1 
ATOM   5238 C C   . SER C 3 148 ? 165.330 184.320 91.493  1.00 128.16 ? 148 SER Q C   1 
ATOM   5239 O O   . SER C 3 148 ? 165.443 184.153 92.712  1.00 127.30 ? 148 SER Q O   1 
ATOM   5240 C CB  . SER C 3 148 ? 162.845 184.130 91.322  1.00 127.97 ? 148 SER Q CB  1 
ATOM   5241 O OG  . SER C 3 148 ? 161.645 184.750 90.892  1.00 127.17 ? 148 SER Q OG  1 
ATOM   5242 N N   . GLY C 3 149 ? 166.277 183.953 90.635  1.00 129.26 ? 149 GLY Q N   1 
ATOM   5243 C CA  . GLY C 3 149 ? 167.509 183.335 91.077  1.00 129.52 ? 149 GLY Q CA  1 
ATOM   5244 C C   . GLY C 3 149 ? 167.463 181.834 91.247  1.00 130.94 ? 149 GLY Q C   1 
ATOM   5245 O O   . GLY C 3 149 ? 168.446 181.254 91.722  1.00 130.79 ? 149 GLY Q O   1 
ATOM   5246 N N   . THR C 3 150 ? 166.358 181.187 90.884  1.00 133.05 ? 150 THR Q N   1 
ATOM   5247 C CA  . THR C 3 150 ? 166.231 179.739 90.967  1.00 132.89 ? 150 THR Q CA  1 
ATOM   5248 C C   . THR C 3 150 ? 165.766 179.197 89.623  1.00 131.95 ? 150 THR Q C   1 
ATOM   5249 O O   . THR C 3 150 ? 165.189 179.916 88.805  1.00 131.00 ? 150 THR Q O   1 
ATOM   5250 C CB  . THR C 3 150 ? 165.247 179.306 92.067  1.00 131.67 ? 150 THR Q CB  1 
ATOM   5251 O OG1 . THR C 3 150 ? 163.913 179.670 91.690  1.00 131.45 ? 150 THR Q OG1 1 
ATOM   5252 C CG2 . THR C 3 150 ? 165.594 179.964 93.395  1.00 130.87 ? 150 THR Q CG2 1 
ATOM   5253 N N   . ALA C 3 151 ? 166.040 177.914 89.398  1.00 122.93 ? 151 ALA Q N   1 
ATOM   5254 C CA  . ALA C 3 151 ? 165.592 177.229 88.196  1.00 122.10 ? 151 ALA Q CA  1 
ATOM   5255 C C   . ALA C 3 151 ? 165.207 175.802 88.551  1.00 121.68 ? 151 ALA Q C   1 
ATOM   5256 O O   . ALA C 3 151 ? 165.772 175.201 89.468  1.00 121.72 ? 151 ALA Q O   1 
ATOM   5257 C CB  . ALA C 3 151 ? 166.669 177.230 87.104  1.00 123.06 ? 151 ALA Q CB  1 
ATOM   5258 N N   . SER C 3 152 ? 164.233 175.266 87.817  1.00 121.71 ? 152 SER Q N   1 
ATOM   5259 C CA  . SER C 3 152 ? 163.773 173.900 88.055  1.00 121.98 ? 152 SER Q CA  1 
ATOM   5260 C C   . SER C 3 152 ? 163.116 173.388 86.781  1.00 121.50 ? 152 SER Q C   1 
ATOM   5261 O O   . SER C 3 152 ? 162.012 173.821 86.440  1.00 122.09 ? 152 SER Q O   1 
ATOM   5262 C CB  . SER C 3 152 ? 162.805 173.850 89.232  1.00 120.45 ? 152 SER Q CB  1 
ATOM   5263 O OG  . SER C 3 152 ? 163.460 174.160 90.449  1.00 120.80 ? 152 SER Q OG  1 
ATOM   5264 N N   . VAL C 3 153 ? 163.789 172.473 86.089  1.00 115.41 ? 153 VAL Q N   1 
ATOM   5265 C CA  . VAL C 3 153 ? 163.237 171.810 84.914  1.00 115.54 ? 153 VAL Q CA  1 
ATOM   5266 C C   . VAL C 3 153 ? 162.630 170.488 85.358  1.00 116.22 ? 153 VAL Q C   1 
ATOM   5267 O O   . VAL C 3 153 ? 163.270 169.710 86.076  1.00 117.00 ? 153 VAL Q O   1 
ATOM   5268 C CB  . VAL C 3 153 ? 164.311 171.601 83.832  1.00 114.98 ? 153 VAL Q CB  1 
ATOM   5269 C CG1 . VAL C 3 153 ? 165.573 170.994 84.430  1.00 116.27 ? 153 VAL Q CG1 1 
ATOM   5270 C CG2 . VAL C 3 153 ? 163.771 170.728 82.711  1.00 114.78 ? 153 VAL Q CG2 1 
ATOM   5271 N N   . VAL C 3 154 ? 161.389 170.237 84.948  1.00 113.40 ? 154 VAL Q N   1 
ATOM   5272 C CA  . VAL C 3 154 ? 160.652 169.065 85.398  1.00 112.57 ? 154 VAL Q CA  1 
ATOM   5273 C C   . VAL C 3 154 ? 160.253 168.223 84.197  1.00 114.20 ? 154 VAL Q C   1 
ATOM   5274 O O   . VAL C 3 154 ? 160.089 168.725 83.080  1.00 113.31 ? 154 VAL Q O   1 
ATOM   5275 C CB  . VAL C 3 154 ? 159.409 169.451 86.227  1.00 111.18 ? 154 VAL Q CB  1 
ATOM   5276 C CG1 . VAL C 3 154 ? 159.819 170.248 87.454  1.00 112.49 ? 154 VAL Q CG1 1 
ATOM   5277 C CG2 . VAL C 3 154 ? 158.427 170.236 85.377  1.00 112.51 ? 154 VAL Q CG2 1 
ATOM   5278 N N   . CYS C 3 155 ? 160.100 166.924 84.440  1.00 117.19 ? 155 CYS Q N   1 
ATOM   5279 C CA  . CYS C 3 155 ? 159.690 165.962 83.430  1.00 116.00 ? 155 CYS Q CA  1 
ATOM   5280 C C   . CYS C 3 155 ? 158.412 165.274 83.883  1.00 115.49 ? 155 CYS Q C   1 
ATOM   5281 O O   . CYS C 3 155 ? 158.281 164.899 85.052  1.00 116.60 ? 155 CYS Q O   1 
ATOM   5282 C CB  . CYS C 3 155 ? 160.784 164.923 83.179  1.00 117.89 ? 155 CYS Q CB  1 
ATOM   5283 S SG  . CYS C 3 155 ? 160.742 164.175 81.541  1.00 122.75 ? 155 CYS Q SG  1 
ATOM   5284 N N   . LEU C 3 156 ? 157.474 165.110 82.957  1.00 107.79 ? 156 LEU Q N   1 
ATOM   5285 C CA  . LEU C 3 156 ? 156.175 164.524 83.251  1.00 108.41 ? 156 LEU Q CA  1 
ATOM   5286 C C   . LEU C 3 156 ? 156.045 163.178 82.555  1.00 108.80 ? 156 LEU Q C   1 
ATOM   5287 O O   . LEU C 3 156 ? 156.221 163.084 81.336  1.00 110.25 ? 156 LEU Q O   1 
ATOM   5288 C CB  . LEU C 3 156 ? 155.043 165.453 82.809  1.00 108.52 ? 156 LEU Q CB  1 
ATOM   5289 C CG  . LEU C 3 156 ? 153.675 164.800 82.602  1.00 108.97 ? 156 LEU Q CG  1 
ATOM   5290 C CD1 . LEU C 3 156 ? 153.017 164.494 83.937  1.00 108.81 ? 156 LEU Q CD1 1 
ATOM   5291 C CD2 . LEU C 3 156 ? 152.779 165.681 81.748  1.00 107.82 ? 156 LEU Q CD2 1 
ATOM   5292 N N   . LEU C 3 157 ? 155.741 162.143 83.331  1.00 101.73 ? 157 LEU Q N   1 
ATOM   5293 C CA  . LEU C 3 157 ? 155.409 160.825 82.807  1.00 102.90 ? 157 LEU Q CA  1 
ATOM   5294 C C   . LEU C 3 157 ? 153.931 160.585 83.071  1.00 102.26 ? 157 LEU Q C   1 
ATOM   5295 O O   . LEU C 3 157 ? 153.477 160.691 84.215  1.00 101.74 ? 157 LEU Q O   1 
ATOM   5296 C CB  . LEU C 3 157 ? 156.260 159.725 83.445  1.00 103.55 ? 157 LEU Q CB  1 
ATOM   5297 C CG  . LEU C 3 157 ? 157.762 159.564 83.171  1.00 103.12 ? 157 LEU Q CG  1 
ATOM   5298 C CD1 . LEU C 3 157 ? 158.544 160.871 83.168  1.00 103.15 ? 157 LEU Q CD1 1 
ATOM   5299 C CD2 . LEU C 3 157 ? 158.364 158.588 84.170  1.00 102.53 ? 157 LEU Q CD2 1 
ATOM   5300 N N   . ASN C 3 158 ? 153.184 160.268 82.019  1.00 104.53 ? 158 ASN Q N   1 
ATOM   5301 C CA  . ASN C 3 158 ? 151.735 160.163 82.093  1.00 105.65 ? 158 ASN Q CA  1 
ATOM   5302 C C   . ASN C 3 158 ? 151.294 158.763 81.692  1.00 107.63 ? 158 ASN Q C   1 
ATOM   5303 O O   . ASN C 3 158 ? 151.754 158.229 80.676  1.00 108.50 ? 158 ASN Q O   1 
ATOM   5304 C CB  . ASN C 3 158 ? 151.073 161.211 81.192  1.00 105.57 ? 158 ASN Q CB  1 
ATOM   5305 C CG  . ASN C 3 158 ? 149.902 161.903 81.864  1.00 106.67 ? 158 ASN Q CG  1 
ATOM   5306 O OD1 . ASN C 3 158 ? 149.161 161.291 82.633  1.00 107.70 ? 158 ASN Q OD1 1 
ATOM   5307 N ND2 . ASN C 3 158 ? 149.730 163.187 81.575  1.00 104.86 ? 158 ASN Q ND2 1 
ATOM   5308 N N   . ASN C 3 159 ? 150.408 158.175 82.497  1.00 102.89 ? 159 ASN Q N   1 
ATOM   5309 C CA  . ASN C 3 159 ? 149.710 156.931 82.168  1.00 102.62 ? 159 ASN Q CA  1 
ATOM   5310 C C   . ASN C 3 159 ? 150.679 155.766 81.944  1.00 103.46 ? 159 ASN Q C   1 
ATOM   5311 O O   . ASN C 3 159 ? 150.799 155.223 80.845  1.00 104.05 ? 159 ASN Q O   1 
ATOM   5312 C CB  . ASN C 3 159 ? 148.803 157.132 80.949  1.00 103.68 ? 159 ASN Q CB  1 
ATOM   5313 C CG  . ASN C 3 159 ? 147.961 158.388 81.051  1.00 104.40 ? 159 ASN Q CG  1 
ATOM   5314 O OD1 . ASN C 3 159 ? 147.520 158.768 82.135  1.00 102.76 ? 159 ASN Q OD1 1 
ATOM   5315 N ND2 . ASN C 3 159 ? 147.733 159.039 79.917  1.00 103.62 ? 159 ASN Q ND2 1 
ATOM   5316 N N   . PHE C 3 160 ? 151.372 155.387 83.014  1.00 102.61 ? 160 PHE Q N   1 
ATOM   5317 C CA  . PHE C 3 160 ? 152.201 154.188 83.030  1.00 101.99 ? 160 PHE Q CA  1 
ATOM   5318 C C   . PHE C 3 160 ? 151.757 153.299 84.182  1.00 104.59 ? 160 PHE Q C   1 
ATOM   5319 O O   . PHE C 3 160 ? 151.675 153.755 85.327  1.00 105.19 ? 160 PHE Q O   1 
ATOM   5320 C CB  . PHE C 3 160 ? 153.688 154.528 83.162  1.00 102.67 ? 160 PHE Q CB  1 
ATOM   5321 C CG  . PHE C 3 160 ? 154.013 155.406 84.333  1.00 101.69 ? 160 PHE Q CG  1 
ATOM   5322 C CD1 . PHE C 3 160 ? 153.760 156.765 84.296  1.00 101.81 ? 160 PHE Q CD1 1 
ATOM   5323 C CD2 . PHE C 3 160 ? 154.602 154.870 85.464  1.00 103.22 ? 160 PHE Q CD2 1 
ATOM   5324 C CE1 . PHE C 3 160 ? 154.069 157.565 85.372  1.00 104.07 ? 160 PHE Q CE1 1 
ATOM   5325 C CE2 . PHE C 3 160 ? 154.912 155.666 86.544  1.00 103.71 ? 160 PHE Q CE2 1 
ATOM   5326 C CZ  . PHE C 3 160 ? 154.646 157.013 86.498  1.00 104.22 ? 160 PHE Q CZ  1 
ATOM   5327 N N   . TYR C 3 161 ? 151.465 152.036 83.878  1.00 102.77 ? 161 TYR Q N   1 
ATOM   5328 C CA  . TYR C 3 161 ? 150.889 151.122 84.859  1.00 102.12 ? 161 TYR Q CA  1 
ATOM   5329 C C   . TYR C 3 161 ? 151.895 150.558 85.865  1.00 102.42 ? 161 TYR Q C   1 
ATOM   5330 O O   . TYR C 3 161 ? 151.722 150.765 87.073  1.00 102.53 ? 161 TYR Q O   1 
ATOM   5331 C CB  . TYR C 3 161 ? 150.169 149.975 84.145  1.00 99.37  ? 161 TYR Q CB  1 
ATOM   5332 C CG  . TYR C 3 161 ? 148.686 150.194 83.985  1.00 100.93 ? 161 TYR Q CG  1 
ATOM   5333 C CD1 . TYR C 3 161 ? 148.199 151.221 83.188  1.00 101.53 ? 161 TYR Q CD1 1 
ATOM   5334 C CD2 . TYR C 3 161 ? 147.773 149.377 84.633  1.00 99.75  ? 161 TYR Q CD2 1 
ATOM   5335 C CE1 . TYR C 3 161 ? 146.841 151.425 83.039  1.00 102.27 ? 161 TYR Q CE1 1 
ATOM   5336 C CE2 . TYR C 3 161 ? 146.416 149.574 84.491  1.00 101.62 ? 161 TYR Q CE2 1 
ATOM   5337 C CZ  . TYR C 3 161 ? 145.954 150.598 83.694  1.00 103.11 ? 161 TYR Q CZ  1 
ATOM   5338 O OH  . TYR C 3 161 ? 144.600 150.795 83.552  1.00 101.31 ? 161 TYR Q OH  1 
ATOM   5339 N N   . PRO C 3 162 ? 152.944 149.850 85.441  1.00 106.94 ? 162 PRO Q N   1 
ATOM   5340 C CA  . PRO C 3 162 ? 153.712 149.026 86.383  1.00 107.84 ? 162 PRO Q CA  1 
ATOM   5341 C C   . PRO C 3 162 ? 154.705 149.785 87.250  1.00 108.29 ? 162 PRO Q C   1 
ATOM   5342 O O   . PRO C 3 162 ? 155.549 149.141 87.879  1.00 107.77 ? 162 PRO Q O   1 
ATOM   5343 C CB  . PRO C 3 162 ? 154.454 148.044 85.455  1.00 106.79 ? 162 PRO Q CB  1 
ATOM   5344 C CG  . PRO C 3 162 ? 153.967 148.338 84.055  1.00 107.86 ? 162 PRO Q CG  1 
ATOM   5345 C CD  . PRO C 3 162 ? 153.513 149.748 84.089  1.00 106.58 ? 162 PRO Q CD  1 
ATOM   5346 N N   . ARG C 3 163 ? 154.626 151.110 87.317  1.00 110.91 ? 163 ARG Q N   1 
ATOM   5347 C CA  . ARG C 3 163 ? 155.584 151.948 88.070  1.00 110.85 ? 163 ARG Q CA  1 
ATOM   5348 C C   . ARG C 3 163 ? 156.987 151.611 87.558  1.00 112.76 ? 163 ARG Q C   1 
ATOM   5349 O O   . ARG C 3 163 ? 157.170 151.429 86.344  1.00 114.69 ? 163 ARG Q O   1 
ATOM   5350 C CB  . ARG C 3 163 ? 155.415 151.770 89.568  1.00 111.13 ? 163 ARG Q CB  1 
ATOM   5351 C CG  . ARG C 3 163 ? 154.032 151.390 90.036  1.00 110.44 ? 163 ARG Q CG  1 
ATOM   5352 C CD  . ARG C 3 163 ? 153.953 151.450 91.553  1.00 112.54 ? 163 ARG Q CD  1 
ATOM   5353 N NE  . ARG C 3 163 ? 154.047 152.820 92.043  1.00 112.46 ? 163 ARG Q NE  1 
ATOM   5354 C CZ  . ARG C 3 163 ? 154.080 153.156 93.325  1.00 111.72 ? 163 ARG Q CZ  1 
ATOM   5355 N NH1 . ARG C 3 163 ? 154.040 152.242 94.281  1.00 111.11 ? 163 ARG Q NH1 1 
ATOM   5356 N NH2 . ARG C 3 163 ? 154.158 154.442 93.657  1.00 110.59 ? 163 ARG Q NH2 1 
ATOM   5357 N N   . GLU C 3 164 ? 157.978 151.523 88.448  1.00 121.54 ? 164 GLU Q N   1 
ATOM   5358 C CA  . GLU C 3 164 ? 159.340 151.120 88.096  1.00 122.99 ? 164 GLU Q CA  1 
ATOM   5359 C C   . GLU C 3 164 ? 159.903 151.990 86.977  1.00 123.66 ? 164 GLU Q C   1 
ATOM   5360 O O   . GLU C 3 164 ? 160.620 151.519 86.091  1.00 124.70 ? 164 GLU Q O   1 
ATOM   5361 C CB  . GLU C 3 164 ? 159.394 149.639 87.720  1.00 122.68 ? 164 GLU Q CB  1 
ATOM   5362 C CG  . GLU C 3 164 ? 158.882 148.709 88.806  1.00 121.87 ? 164 GLU Q CG  1 
ATOM   5363 C CD  . GLU C 3 164 ? 159.262 147.265 88.559  1.00 123.29 ? 164 GLU Q CD  1 
ATOM   5364 O OE1 . GLU C 3 164 ? 160.013 147.005 87.595  1.00 122.54 ? 164 GLU Q OE1 1 
ATOM   5365 O OE2 . GLU C 3 164 ? 158.812 146.389 89.326  1.00 124.11 ? 164 GLU Q OE2 1 
ATOM   5366 N N   . ALA C 3 165 ? 159.575 153.276 87.020  1.00 118.57 ? 165 ALA Q N   1 
ATOM   5367 C CA  . ALA C 3 165 ? 160.040 154.237 86.031  1.00 117.33 ? 165 ALA Q CA  1 
ATOM   5368 C C   . ALA C 3 165 ? 161.213 155.011 86.615  1.00 119.37 ? 165 ALA Q C   1 
ATOM   5369 O O   . ALA C 3 165 ? 161.092 155.615 87.687  1.00 119.99 ? 165 ALA Q O   1 
ATOM   5370 C CB  . ALA C 3 165 ? 158.915 155.186 85.619  1.00 116.71 ? 165 ALA Q CB  1 
ATOM   5371 N N   . LYS C 3 166 ? 162.341 154.985 85.917  1.00 125.92 ? 166 LYS Q N   1 
ATOM   5372 C CA  . LYS C 3 166 ? 163.533 155.711 86.326  1.00 125.65 ? 166 LYS Q CA  1 
ATOM   5373 C C   . LYS C 3 166 ? 163.637 156.994 85.515  1.00 125.97 ? 166 LYS Q C   1 
ATOM   5374 O O   . LYS C 3 166 ? 163.279 157.025 84.334  1.00 125.35 ? 166 LYS Q O   1 
ATOM   5375 N N   . VAL C 3 167 ? 164.120 158.053 86.157  1.00 121.00 ? 167 VAL Q N   1 
ATOM   5376 C CA  . VAL C 3 167 ? 164.273 159.357 85.525  1.00 121.56 ? 167 VAL Q CA  1 
ATOM   5377 C C   . VAL C 3 167 ? 165.754 159.707 85.516  1.00 122.19 ? 167 VAL Q C   1 
ATOM   5378 O O   . VAL C 3 167 ? 166.403 159.718 86.570  1.00 121.19 ? 167 VAL Q O   1 
ATOM   5379 C CB  . VAL C 3 167 ? 163.454 160.440 86.245  1.00 120.95 ? 167 VAL Q CB  1 
ATOM   5380 C CG1 . VAL C 3 167 ? 163.610 161.780 85.542  1.00 120.99 ? 167 VAL Q CG1 1 
ATOM   5381 C CG2 . VAL C 3 167 ? 161.990 160.037 86.313  1.00 120.39 ? 167 VAL Q CG2 1 
ATOM   5382 N N   . GLN C 3 168 ? 166.286 159.980 84.328  1.00 124.50 ? 168 GLN Q N   1 
ATOM   5383 C CA  . GLN C 3 168 ? 167.656 160.440 84.159  1.00 124.17 ? 168 GLN Q CA  1 
ATOM   5384 C C   . GLN C 3 168 ? 167.639 161.718 83.335  1.00 125.12 ? 168 GLN Q C   1 
ATOM   5385 O O   . GLN C 3 168 ? 166.822 161.865 82.422  1.00 124.78 ? 168 GLN Q O   1 
ATOM   5386 C CB  . GLN C 3 168 ? 168.528 159.380 83.476  1.00 123.74 ? 168 GLN Q CB  1 
ATOM   5387 N N   . TRP C 3 169 ? 168.541 162.640 83.660  1.00 125.11 ? 169 TRP Q N   1 
ATOM   5388 C CA  . TRP C 3 169 ? 168.546 163.966 83.053  1.00 125.37 ? 169 TRP Q CA  1 
ATOM   5389 C C   . TRP C 3 169 ? 169.649 164.174 82.029  1.00 125.70 ? 169 TRP Q C   1 
ATOM   5390 O O   . TRP C 3 169 ? 169.400 164.783 80.987  1.00 125.61 ? 169 TRP Q O   1 
ATOM   5391 C CB  . TRP C 3 169 ? 168.654 165.038 84.142  1.00 124.61 ? 169 TRP Q CB  1 
ATOM   5392 C CG  . TRP C 3 169 ? 167.479 165.039 85.067  1.00 124.84 ? 169 TRP Q CG  1 
ATOM   5393 C CD1 . TRP C 3 169 ? 167.417 164.495 86.315  1.00 124.03 ? 169 TRP Q CD1 1 
ATOM   5394 C CD2 . TRP C 3 169 ? 166.188 165.602 84.809  1.00 124.59 ? 169 TRP Q CD2 1 
ATOM   5395 N NE1 . TRP C 3 169 ? 166.168 164.690 86.854  1.00 124.31 ? 169 TRP Q NE1 1 
ATOM   5396 C CE2 . TRP C 3 169 ? 165.395 165.367 85.948  1.00 124.16 ? 169 TRP Q CE2 1 
ATOM   5397 C CE3 . TRP C 3 169 ? 165.627 166.285 83.727  1.00 123.25 ? 169 TRP Q CE3 1 
ATOM   5398 C CZ2 . TRP C 3 169 ? 164.073 165.789 86.036  1.00 123.64 ? 169 TRP Q CZ2 1 
ATOM   5399 C CZ3 . TRP C 3 169 ? 164.315 166.703 83.816  1.00 122.51 ? 169 TRP Q CZ3 1 
ATOM   5400 C CH2 . TRP C 3 169 ? 163.552 166.455 84.962  1.00 123.42 ? 169 TRP Q CH2 1 
ATOM   5401 N N   . LYS C 3 170 ? 170.858 163.685 82.295  1.00 134.08 ? 170 LYS Q N   1 
ATOM   5402 C CA  . LYS C 3 170 ? 171.995 163.834 81.387  1.00 134.62 ? 170 LYS Q CA  1 
ATOM   5403 C C   . LYS C 3 170 ? 172.240 165.307 81.054  1.00 134.66 ? 170 LYS Q C   1 
ATOM   5404 O O   . LYS C 3 170 ? 172.184 165.736 79.901  1.00 134.02 ? 170 LYS Q O   1 
ATOM   5405 C CB  . LYS C 3 170 ? 171.793 163.007 80.113  1.00 133.71 ? 170 LYS Q CB  1 
ATOM   5406 C CG  . LYS C 3 170 ? 172.446 161.637 80.149  1.00 133.72 ? 170 LYS Q CG  1 
ATOM   5407 C CD  . LYS C 3 170 ? 172.277 160.913 78.823  1.00 133.92 ? 170 LYS Q CD  1 
ATOM   5408 C CE  . LYS C 3 170 ? 173.247 159.748 78.701  1.00 133.77 ? 170 LYS Q CE  1 
ATOM   5409 N NZ  . LYS C 3 170 ? 173.142 158.815 79.855  1.00 133.87 ? 170 LYS Q NZ  1 
ATOM   5410 N N   . VAL C 3 171 ? 172.508 166.083 82.101  1.00 139.63 ? 171 VAL Q N   1 
ATOM   5411 C CA  . VAL C 3 171 ? 172.775 167.509 81.937  1.00 140.63 ? 171 VAL Q CA  1 
ATOM   5412 C C   . VAL C 3 171 ? 174.163 167.663 81.322  1.00 141.40 ? 171 VAL Q C   1 
ATOM   5413 O O   . VAL C 3 171 ? 175.174 167.420 81.986  1.00 140.84 ? 171 VAL Q O   1 
ATOM   5414 C CB  . VAL C 3 171 ? 172.669 168.259 83.269  1.00 140.69 ? 171 VAL Q CB  1 
ATOM   5415 C CG1 . VAL C 3 171 ? 172.952 169.738 83.067  1.00 140.02 ? 171 VAL Q CG1 1 
ATOM   5416 C CG2 . VAL C 3 171 ? 171.294 168.054 83.883  1.00 140.45 ? 171 VAL Q CG2 1 
ATOM   5417 N N   . ASP C 3 172 ? 174.210 168.076 80.055  1.00 145.28 ? 172 ASP Q N   1 
ATOM   5418 C CA  . ASP C 3 172 ? 175.459 168.207 79.303  1.00 144.63 ? 172 ASP Q CA  1 
ATOM   5419 C C   . ASP C 3 172 ? 176.242 166.895 79.307  1.00 144.34 ? 172 ASP Q C   1 
ATOM   5420 O O   . ASP C 3 172 ? 177.445 166.859 79.576  1.00 144.61 ? 172 ASP Q O   1 
ATOM   5421 C CB  . ASP C 3 172 ? 176.311 169.356 79.844  1.00 144.98 ? 172 ASP Q CB  1 
ATOM   5422 C CG  . ASP C 3 172 ? 175.741 170.717 79.500  1.00 145.11 ? 172 ASP Q CG  1 
ATOM   5423 O OD1 . ASP C 3 172 ? 174.518 170.810 79.269  1.00 144.98 ? 172 ASP Q OD1 1 
ATOM   5424 O OD2 . ASP C 3 172 ? 176.517 171.694 79.460  1.00 144.47 ? 172 ASP Q OD2 1 
ATOM   5425 N N   . ASN C 3 173 ? 175.534 165.805 79.003  1.00 141.19 ? 173 ASN Q N   1 
ATOM   5426 C CA  . ASN C 3 173 ? 176.116 164.461 78.958  1.00 141.22 ? 173 ASN Q CA  1 
ATOM   5427 C C   . ASN C 3 173 ? 176.766 164.088 80.289  1.00 141.04 ? 173 ASN Q C   1 
ATOM   5428 O O   . ASN C 3 173 ? 177.807 163.429 80.330  1.00 141.02 ? 173 ASN Q O   1 
ATOM   5429 C CB  . ASN C 3 173 ? 177.117 164.326 77.807  1.00 141.04 ? 173 ASN Q CB  1 
ATOM   5430 C CG  . ASN C 3 173 ? 176.449 164.351 76.447  1.00 141.30 ? 173 ASN Q CG  1 
ATOM   5431 O OD1 . ASN C 3 173 ? 175.338 163.847 76.279  1.00 140.98 ? 173 ASN Q OD1 1 
ATOM   5432 N ND2 . ASN C 3 173 ? 177.125 164.940 75.466  1.00 141.02 ? 173 ASN Q ND2 1 
ATOM   5433 N N   . ALA C 3 174 ? 176.148 164.516 81.387  1.00 136.68 ? 174 ALA Q N   1 
ATOM   5434 C CA  . ALA C 3 174 ? 176.594 164.172 82.730  1.00 136.09 ? 174 ALA Q CA  1 
ATOM   5435 C C   . ALA C 3 174 ? 175.405 163.642 83.515  1.00 136.26 ? 174 ALA Q C   1 
ATOM   5436 O O   . ALA C 3 174 ? 174.346 164.276 83.546  1.00 136.11 ? 174 ALA Q O   1 
ATOM   5437 C CB  . ALA C 3 174 ? 177.213 165.378 83.443  1.00 135.08 ? 174 ALA Q CB  1 
ATOM   5438 N N   . LEU C 3 175 ? 175.584 162.487 84.149  1.00 127.52 ? 175 LEU Q N   1 
ATOM   5439 C CA  . LEU C 3 175 ? 174.498 161.822 84.867  1.00 125.89 ? 175 LEU Q CA  1 
ATOM   5440 C C   . LEU C 3 175 ? 174.173 162.604 86.133  1.00 126.29 ? 175 LEU Q C   1 
ATOM   5441 O O   . LEU C 3 175 ? 174.910 162.552 87.120  1.00 125.61 ? 175 LEU Q O   1 
ATOM   5442 C CB  . LEU C 3 175 ? 174.883 160.383 85.190  1.00 125.72 ? 175 LEU Q CB  1 
ATOM   5443 C CG  . LEU C 3 175 ? 174.804 159.379 84.037  1.00 126.21 ? 175 LEU Q CG  1 
ATOM   5444 C CD1 . LEU C 3 175 ? 174.567 157.974 84.567  1.00 126.12 ? 175 LEU Q CD1 1 
ATOM   5445 C CD2 . LEU C 3 175 ? 173.717 159.769 83.048  1.00 125.31 ? 175 LEU Q CD2 1 
ATOM   5446 N N   . GLN C 3 176 ? 173.064 163.337 86.106  1.00 119.97 ? 176 GLN Q N   1 
ATOM   5447 C CA  . GLN C 3 176 ? 172.597 164.032 87.296  1.00 118.23 ? 176 GLN Q CA  1 
ATOM   5448 C C   . GLN C 3 176 ? 172.017 163.037 88.293  1.00 117.62 ? 176 GLN Q C   1 
ATOM   5449 O O   . GLN C 3 176 ? 171.383 162.049 87.912  1.00 117.17 ? 176 GLN Q O   1 
ATOM   5450 C CB  . GLN C 3 176 ? 171.548 165.080 86.924  1.00 117.25 ? 176 GLN Q CB  1 
ATOM   5451 N N   . SER C 3 177 ? 172.240 163.300 89.578  1.00 109.91 ? 177 SER Q N   1 
ATOM   5452 C CA  . SER C 3 177 ? 171.778 162.399 90.624  1.00 109.56 ? 177 SER Q CA  1 
ATOM   5453 C C   . SER C 3 177 ? 171.639 163.173 91.925  1.00 109.30 ? 177 SER Q C   1 
ATOM   5454 O O   . SER C 3 177 ? 172.188 164.267 92.081  1.00 108.45 ? 177 SER Q O   1 
ATOM   5455 C CB  . SER C 3 177 ? 172.730 161.211 90.802  1.00 108.55 ? 177 SER Q CB  1 
ATOM   5456 O OG  . SER C 3 177 ? 172.277 160.342 91.825  1.00 108.42 ? 177 SER Q OG  1 
ATOM   5457 N N   . GLY C 3 178 ? 170.892 162.590 92.853  1.00 105.32 ? 178 GLY Q N   1 
ATOM   5458 C CA  . GLY C 3 178 ? 170.723 163.174 94.184  1.00 104.89 ? 178 GLY Q CA  1 
ATOM   5459 C C   . GLY C 3 178 ? 169.781 164.348 94.304  1.00 105.39 ? 178 GLY Q C   1 
ATOM   5460 O O   . GLY C 3 178 ? 168.866 164.325 95.132  1.00 104.94 ? 178 GLY Q O   1 
ATOM   5461 N N   . ASN C 3 179 ? 169.982 165.387 93.490  1.00 104.74 ? 179 ASN Q N   1 
ATOM   5462 C CA  . ASN C 3 179 ? 169.170 166.594 93.582  1.00 104.14 ? 179 ASN Q CA  1 
ATOM   5463 C C   . ASN C 3 179 ? 167.758 166.410 93.043  1.00 104.82 ? 179 ASN Q C   1 
ATOM   5464 O O   . ASN C 3 179 ? 166.908 167.273 93.285  1.00 104.85 ? 179 ASN Q O   1 
ATOM   5465 C CB  . ASN C 3 179 ? 169.856 167.741 92.838  1.00 102.97 ? 179 ASN Q CB  1 
ATOM   5466 N N   . SER C 3 180 ? 167.487 165.323 92.325  1.00 105.69 ? 180 SER Q N   1 
ATOM   5467 C CA  . SER C 3 180 ? 166.167 165.122 91.743  1.00 105.96 ? 180 SER Q CA  1 
ATOM   5468 C C   . SER C 3 180 ? 165.153 164.759 92.820  1.00 104.71 ? 180 SER Q C   1 
ATOM   5469 O O   . SER C 3 180 ? 165.410 163.898 93.668  1.00 102.88 ? 180 SER Q O   1 
ATOM   5470 C CB  . SER C 3 180 ? 166.219 164.028 90.678  1.00 105.54 ? 180 SER Q CB  1 
ATOM   5471 O OG  . SER C 3 180 ? 167.023 164.419 89.579  1.00 105.67 ? 180 SER Q OG  1 
ATOM   5472 N N   . GLN C 3 181 ? 163.999 165.420 92.785  1.00 101.50 ? 181 GLN Q N   1 
ATOM   5473 C CA  . GLN C 3 181 ? 162.872 165.113 93.656  1.00 100.19 ? 181 GLN Q CA  1 
ATOM   5474 C C   . GLN C 3 181 ? 161.689 164.711 92.789  1.00 100.22 ? 181 GLN Q C   1 
ATOM   5475 O O   . GLN C 3 181 ? 161.335 165.429 91.849  1.00 100.38 ? 181 GLN Q O   1 
ATOM   5476 C CB  . GLN C 3 181 ? 162.505 166.311 94.536  1.00 100.86 ? 181 GLN Q CB  1 
ATOM   5477 C CG  . GLN C 3 181 ? 163.646 166.829 95.395  1.00 100.98 ? 181 GLN Q CG  1 
ATOM   5478 C CD  . GLN C 3 181 ? 163.474 166.488 96.861  1.00 100.66 ? 181 GLN Q CD  1 
ATOM   5479 O OE1 . GLN C 3 181 ? 162.353 166.400 97.362  1.00 100.87 ? 181 GLN Q OE1 1 
ATOM   5480 N NE2 . GLN C 3 181 ? 164.587 166.295 97.559  1.00 100.55 ? 181 GLN Q NE2 1 
ATOM   5481 N N   . GLU C 3 182 ? 161.081 163.571 93.106  1.00 90.71  ? 182 GLU Q N   1 
ATOM   5482 C CA  . GLU C 3 182 ? 160.008 163.016 92.296  1.00 92.02  ? 182 GLU Q CA  1 
ATOM   5483 C C   . GLU C 3 182 ? 158.820 162.654 93.173  1.00 91.46  ? 182 GLU Q C   1 
ATOM   5484 O O   . GLU C 3 182 ? 158.973 162.321 94.351  1.00 91.48  ? 182 GLU Q O   1 
ATOM   5485 C CB  . GLU C 3 182 ? 160.473 161.775 91.523  1.00 91.95  ? 182 GLU Q CB  1 
ATOM   5486 N N   . SER C 3 183 ? 157.631 162.725 92.578  1.00 89.29  ? 183 SER Q N   1 
ATOM   5487 C CA  . SER C 3 183 ? 156.394 162.346 93.242  1.00 88.79  ? 183 SER Q CA  1 
ATOM   5488 C C   . SER C 3 183 ? 155.500 161.622 92.249  1.00 89.08  ? 183 SER Q C   1 
ATOM   5489 O O   . SER C 3 183 ? 155.539 161.890 91.046  1.00 88.79  ? 183 SER Q O   1 
ATOM   5490 C CB  . SER C 3 183 ? 155.661 163.563 93.813  1.00 86.65  ? 183 SER Q CB  1 
ATOM   5491 O OG  . SER C 3 183 ? 155.476 164.553 92.817  1.00 86.46  ? 183 SER Q OG  1 
ATOM   5492 N N   . VAL C 3 184 ? 154.687 160.705 92.766  1.00 81.54  ? 184 VAL Q N   1 
ATOM   5493 C CA  . VAL C 3 184 ? 153.785 159.897 91.955  1.00 79.04  ? 184 VAL Q CA  1 
ATOM   5494 C C   . VAL C 3 184 ? 152.384 160.027 92.531  1.00 80.97  ? 184 VAL Q C   1 
ATOM   5495 O O   . VAL C 3 184 ? 152.188 159.856 93.739  1.00 81.18  ? 184 VAL Q O   1 
ATOM   5496 C CB  . VAL C 3 184 ? 154.228 158.421 91.911  1.00 81.24  ? 184 VAL Q CB  1 
ATOM   5497 C CG1 . VAL C 3 184 ? 153.044 157.504 91.676  1.00 81.69  ? 184 VAL Q CG1 1 
ATOM   5498 C CG2 . VAL C 3 184 ? 155.278 158.214 90.837  1.00 82.25  ? 184 VAL Q CG2 1 
ATOM   5499 N N   . THR C 3 185 ? 151.417 160.339 91.675  1.00 81.27  ? 185 THR Q N   1 
ATOM   5500 C CA  . THR C 3 185 ? 150.040 160.460 92.122  1.00 79.86  ? 185 THR Q CA  1 
ATOM   5501 C C   . THR C 3 185 ? 149.442 159.084 92.400  1.00 79.44  ? 185 THR Q C   1 
ATOM   5502 O O   . THR C 3 185 ? 149.963 158.049 91.978  1.00 80.23  ? 185 THR Q O   1 
ATOM   5503 C CB  . THR C 3 185 ? 149.195 161.192 91.081  1.00 75.28  ? 185 THR Q CB  1 
ATOM   5504 O OG1 . THR C 3 185 ? 147.895 161.457 91.623  1.00 77.44  ? 185 THR Q OG1 1 
ATOM   5505 C CG2 . THR C 3 185 ? 149.051 160.348 89.831  1.00 74.87  ? 185 THR Q CG2 1 
ATOM   5506 N N   . GLU C 3 186 ? 148.327 159.082 93.125  1.00 80.28  ? 186 GLU Q N   1 
ATOM   5507 C CA  . GLU C 3 186 ? 147.637 157.839 93.428  1.00 76.82  ? 186 GLU Q CA  1 
ATOM   5508 C C   . GLU C 3 186 ? 147.040 157.250 92.151  1.00 78.88  ? 186 GLU Q C   1 
ATOM   5509 O O   . GLU C 3 186 ? 147.090 157.846 91.072  1.00 80.66  ? 186 GLU Q O   1 
ATOM   5510 C CB  . GLU C 3 186 ? 146.562 158.073 94.485  1.00 77.26  ? 186 GLU Q CB  1 
ATOM   5511 C CG  . GLU C 3 186 ? 146.372 156.906 95.434  1.00 80.26  ? 186 GLU Q CG  1 
ATOM   5512 C CD  . GLU C 3 186 ? 145.065 156.983 96.193  1.00 79.77  ? 186 GLU Q CD  1 
ATOM   5513 O OE1 . GLU C 3 186 ? 144.413 158.047 96.149  1.00 79.00  ? 186 GLU Q OE1 1 
ATOM   5514 O OE2 . GLU C 3 186 ? 144.685 155.974 96.823  1.00 78.59  ? 186 GLU Q OE2 1 
ATOM   5515 N N   . GLN C 3 187 ? 146.468 156.056 92.275  1.00 84.22  ? 187 GLN Q N   1 
ATOM   5516 C CA  . GLN C 3 187 ? 145.946 155.362 91.107  1.00 85.01  ? 187 GLN Q CA  1 
ATOM   5517 C C   . GLN C 3 187 ? 144.717 156.082 90.570  1.00 87.15  ? 187 GLN Q C   1 
ATOM   5518 O O   . GLN C 3 187 ? 143.826 156.470 91.331  1.00 89.93  ? 187 GLN Q O   1 
ATOM   5519 C CB  . GLN C 3 187 ? 145.622 153.912 91.460  1.00 84.71  ? 187 GLN Q CB  1 
ATOM   5520 C CG  . GLN C 3 187 ? 145.315 153.038 90.261  1.00 85.83  ? 187 GLN Q CG  1 
ATOM   5521 C CD  . GLN C 3 187 ? 145.341 151.563 90.598  1.00 85.13  ? 187 GLN Q CD  1 
ATOM   5522 O OE1 . GLN C 3 187 ? 145.704 151.176 91.706  1.00 85.16  ? 187 GLN Q OE1 1 
ATOM   5523 N NE2 . GLN C 3 187 ? 144.968 150.729 89.638  1.00 84.54  ? 187 GLN Q NE2 1 
ATOM   5524 N N   . ASP C 3 188 ? 144.679 156.265 89.251  1.00 91.55  ? 188 ASP Q N   1 
ATOM   5525 C CA  . ASP C 3 188 ? 143.624 157.053 88.629  1.00 93.12  ? 188 ASP Q CA  1 
ATOM   5526 C C   . ASP C 3 188 ? 142.263 156.416 88.874  1.00 95.64  ? 188 ASP Q C   1 
ATOM   5527 O O   . ASP C 3 188 ? 142.090 155.205 88.712  1.00 96.61  ? 188 ASP Q O   1 
ATOM   5528 C CB  . ASP C 3 188 ? 143.888 157.190 87.131  1.00 95.21  ? 188 ASP Q CB  1 
ATOM   5529 C CG  . ASP C 3 188 ? 143.450 158.533 86.581  1.00 96.55  ? 188 ASP Q CG  1 
ATOM   5530 O OD1 . ASP C 3 188 ? 142.841 159.319 87.338  1.00 96.10  ? 188 ASP Q OD1 1 
ATOM   5531 O OD2 . ASP C 3 188 ? 143.713 158.804 85.391  1.00 96.50  ? 188 ASP Q OD2 1 
ATOM   5532 N N   . SER C 3 189 ? 141.294 157.243 89.272  1.00 103.86 ? 189 SER Q N   1 
ATOM   5533 C CA  . SER C 3 189 ? 139.967 156.731 89.595  1.00 104.08 ? 189 SER Q CA  1 
ATOM   5534 C C   . SER C 3 189 ? 139.280 156.146 88.367  1.00 105.28 ? 189 SER Q C   1 
ATOM   5535 O O   . SER C 3 189 ? 138.620 155.104 88.454  1.00 105.06 ? 189 SER Q O   1 
ATOM   5536 C CB  . SER C 3 189 ? 139.114 157.841 90.208  1.00 104.58 ? 189 SER Q CB  1 
ATOM   5537 O OG  . SER C 3 189 ? 138.881 158.878 89.271  1.00 105.71 ? 189 SER Q OG  1 
ATOM   5538 N N   . LYS C 3 190 ? 139.420 156.801 87.215  1.00 103.40 ? 190 LYS Q N   1 
ATOM   5539 C CA  . LYS C 3 190 ? 138.752 156.357 86.000  1.00 102.31 ? 190 LYS Q CA  1 
ATOM   5540 C C   . LYS C 3 190 ? 139.647 155.542 85.077  1.00 102.47 ? 190 LYS Q C   1 
ATOM   5541 O O   . LYS C 3 190 ? 139.128 154.779 84.256  1.00 102.79 ? 190 LYS Q O   1 
ATOM   5542 C CB  . LYS C 3 190 ? 138.204 157.561 85.225  1.00 100.32 ? 190 LYS Q CB  1 
ATOM   5543 N N   . ASP C 3 191 ? 140.970 155.677 85.192  1.00 99.87  ? 191 ASP Q N   1 
ATOM   5544 C CA  . ASP C 3 191 ? 141.892 154.993 84.297  1.00 100.34 ? 191 ASP Q CA  1 
ATOM   5545 C C   . ASP C 3 191 ? 142.683 153.878 84.960  1.00 101.21 ? 191 ASP Q C   1 
ATOM   5546 O O   . ASP C 3 191 ? 143.217 153.022 84.248  1.00 101.34 ? 191 ASP Q O   1 
ATOM   5547 C CB  . ASP C 3 191 ? 142.883 155.995 83.685  1.00 99.24  ? 191 ASP Q CB  1 
ATOM   5548 C CG  . ASP C 3 191 ? 142.192 157.142 82.980  1.00 100.75 ? 191 ASP Q CG  1 
ATOM   5549 O OD1 . ASP C 3 191 ? 140.980 157.029 82.700  1.00 102.71 ? 191 ASP Q OD1 1 
ATOM   5550 O OD2 . ASP C 3 191 ? 142.861 158.160 82.706  1.00 98.72  ? 191 ASP Q OD2 1 
ATOM   5551 N N   . SER C 3 192 ? 142.772 153.867 86.292  1.00 99.77  ? 192 SER Q N   1 
ATOM   5552 C CA  . SER C 3 192 ? 143.593 152.905 87.029  1.00 97.79  ? 192 SER Q CA  1 
ATOM   5553 C C   . SER C 3 192 ? 145.051 152.950 86.580  1.00 97.56  ? 192 SER Q C   1 
ATOM   5554 O O   . SER C 3 192 ? 145.729 151.922 86.530  1.00 96.49  ? 192 SER Q O   1 
ATOM   5555 C CB  . SER C 3 192 ? 143.038 151.483 86.908  1.00 97.72  ? 192 SER Q CB  1 
ATOM   5556 O OG  . SER C 3 192 ? 141.757 151.384 87.506  1.00 99.16  ? 192 SER Q OG  1 
ATOM   5557 N N   . THR C 3 193 ? 145.539 154.141 86.251  1.00 96.24  ? 193 THR Q N   1 
ATOM   5558 C CA  . THR C 3 193 ? 146.906 154.358 85.801  1.00 94.79  ? 193 THR Q CA  1 
ATOM   5559 C C   . THR C 3 193 ? 147.578 155.389 86.705  1.00 95.44  ? 193 THR Q C   1 
ATOM   5560 O O   . THR C 3 193 ? 146.948 155.986 87.580  1.00 95.29  ? 193 THR Q O   1 
ATOM   5561 C CB  . THR C 3 193 ? 146.934 154.798 84.335  1.00 94.02  ? 193 THR Q CB  1 
ATOM   5562 O OG1 . THR C 3 193 ? 148.241 154.573 83.792  1.00 94.76  ? 193 THR Q OG1 1 
ATOM   5563 C CG2 . THR C 3 193 ? 146.583 156.273 84.208  1.00 94.13  ? 193 THR Q CG2 1 
ATOM   5564 N N   . TYR C 3 194 ? 148.872 155.594 86.489  1.00 92.76  ? 194 TYR Q N   1 
ATOM   5565 C CA  . TYR C 3 194 ? 149.693 156.434 87.350  1.00 91.80  ? 194 TYR Q CA  1 
ATOM   5566 C C   . TYR C 3 194 ? 150.200 157.650 86.582  1.00 92.10  ? 194 TYR Q C   1 
ATOM   5567 O O   . TYR C 3 194 ? 149.952 157.813 85.386  1.00 93.08  ? 194 TYR Q O   1 
ATOM   5568 C CB  . TYR C 3 194 ? 150.870 155.638 87.923  1.00 91.28  ? 194 TYR Q CB  1 
ATOM   5569 C CG  . TYR C 3 194 ? 150.481 154.647 88.992  1.00 91.43  ? 194 TYR Q CG  1 
ATOM   5570 C CD1 . TYR C 3 194 ? 149.194 154.615 89.501  1.00 90.83  ? 194 TYR Q CD1 1 
ATOM   5571 C CD2 . TYR C 3 194 ? 151.402 153.743 89.493  1.00 92.32  ? 194 TYR Q CD2 1 
ATOM   5572 C CE1 . TYR C 3 194 ? 148.838 153.711 90.473  1.00 90.91  ? 194 TYR Q CE1 1 
ATOM   5573 C CE2 . TYR C 3 194 ? 151.048 152.838 90.468  1.00 91.96  ? 194 TYR Q CE2 1 
ATOM   5574 C CZ  . TYR C 3 194 ? 149.766 152.825 90.955  1.00 92.25  ? 194 TYR Q CZ  1 
ATOM   5575 O OH  . TYR C 3 194 ? 149.408 151.922 91.929  1.00 92.19  ? 194 TYR Q OH  1 
ATOM   5576 N N   . SER C 3 195 ? 150.917 158.513 87.300  1.00 95.75  ? 195 SER Q N   1 
ATOM   5577 C CA  . SER C 3 195 ? 151.582 159.666 86.713  1.00 96.72  ? 195 SER Q CA  1 
ATOM   5578 C C   . SER C 3 195 ? 152.808 159.993 87.554  1.00 96.64  ? 195 SER Q C   1 
ATOM   5579 O O   . SER C 3 195 ? 152.903 159.606 88.721  1.00 98.85  ? 195 SER Q O   1 
ATOM   5580 C CB  . SER C 3 195 ? 150.647 160.876 86.619  1.00 98.01  ? 195 SER Q CB  1 
ATOM   5581 O OG  . SER C 3 195 ? 149.485 160.560 85.875  1.00 99.16  ? 195 SER Q OG  1 
ATOM   5582 N N   . LEU C 3 196 ? 153.751 160.708 86.947  1.00 95.91  ? 196 LEU Q N   1 
ATOM   5583 C CA  . LEU C 3 196 ? 155.009 161.021 87.607  1.00 96.78  ? 196 LEU Q CA  1 
ATOM   5584 C C   . LEU C 3 196 ? 155.414 162.450 87.280  1.00 99.09  ? 196 LEU Q C   1 
ATOM   5585 O O   . LEU C 3 196 ? 155.069 162.984 86.223  1.00 99.15  ? 196 LEU Q O   1 
ATOM   5586 C CB  . LEU C 3 196 ? 156.115 160.041 87.186  1.00 96.69  ? 196 LEU Q CB  1 
ATOM   5587 C CG  . LEU C 3 196 ? 157.221 159.685 88.182  1.00 95.70  ? 196 LEU Q CG  1 
ATOM   5588 C CD1 . LEU C 3 196 ? 157.819 158.338 87.828  1.00 97.90  ? 196 LEU Q CD1 1 
ATOM   5589 C CD2 . LEU C 3 196 ? 158.309 160.740 88.209  1.00 96.95  ? 196 LEU Q CD2 1 
ATOM   5590 N N   . SER C 3 197 ? 156.152 163.062 88.204  1.00 97.77  ? 197 SER Q N   1 
ATOM   5591 C CA  . SER C 3 197 ? 156.695 164.402 88.000  1.00 96.17  ? 197 SER Q CA  1 
ATOM   5592 C C   . SER C 3 197 ? 157.967 164.515 88.826  1.00 96.66  ? 197 SER Q C   1 
ATOM   5593 O O   . SER C 3 197 ? 157.908 164.491 90.059  1.00 97.42  ? 197 SER Q O   1 
ATOM   5594 C CB  . SER C 3 197 ? 155.685 165.474 88.395  1.00 95.06  ? 197 SER Q CB  1 
ATOM   5595 N N   . SER C 3 198 ? 159.106 164.635 88.152  1.00 105.05 ? 198 SER Q N   1 
ATOM   5596 C CA  . SER C 3 198 ? 160.403 164.763 88.803  1.00 105.88 ? 198 SER Q CA  1 
ATOM   5597 C C   . SER C 3 198 ? 160.891 166.198 88.674  1.00 106.75 ? 198 SER Q C   1 
ATOM   5598 O O   . SER C 3 198 ? 160.912 166.753 87.571  1.00 107.13 ? 198 SER Q O   1 
ATOM   5599 C CB  . SER C 3 198 ? 161.422 163.803 88.190  1.00 106.70 ? 198 SER Q CB  1 
ATOM   5600 O OG  . SER C 3 198 ? 161.032 162.456 88.382  1.00 106.70 ? 198 SER Q OG  1 
ATOM   5601 N N   . THR C 3 199 ? 161.286 166.791 89.796  1.00 103.84 ? 199 THR Q N   1 
ATOM   5602 C CA  . THR C 3 199 ? 161.755 168.168 89.836  1.00 105.20 ? 199 THR Q CA  1 
ATOM   5603 C C   . THR C 3 199 ? 163.268 168.185 89.992  1.00 105.03 ? 199 THR Q C   1 
ATOM   5604 O O   . THR C 3 199 ? 163.808 167.573 90.920  1.00 103.78 ? 199 THR Q O   1 
ATOM   5605 C CB  . THR C 3 199 ? 161.103 168.942 90.985  1.00 105.75 ? 199 THR Q CB  1 
ATOM   5606 O OG1 . THR C 3 199 ? 161.716 168.568 92.225  1.00 106.39 ? 199 THR Q OG1 1 
ATOM   5607 C CG2 . THR C 3 199 ? 159.613 168.643 91.052  1.00 103.69 ? 199 THR Q CG2 1 
ATOM   5608 N N   . LEU C 3 200 ? 163.945 168.885 89.089  1.00 115.14 ? 200 LEU Q N   1 
ATOM   5609 C CA  . LEU C 3 200 ? 165.395 169.058 89.132  1.00 114.60 ? 200 LEU Q CA  1 
ATOM   5610 C C   . LEU C 3 200 ? 165.673 170.525 89.451  1.00 114.08 ? 200 LEU Q C   1 
ATOM   5611 O O   . LEU C 3 200 ? 165.805 171.358 88.553  1.00 112.88 ? 200 LEU Q O   1 
ATOM   5612 C CB  . LEU C 3 200 ? 166.040 168.632 87.817  1.00 113.66 ? 200 LEU Q CB  1 
ATOM   5613 C CG  . LEU C 3 200 ? 167.570 168.623 87.789  1.00 114.34 ? 200 LEU Q CG  1 
ATOM   5614 C CD1 . LEU C 3 200 ? 168.111 167.294 88.286  1.00 113.36 ? 200 LEU Q CD1 1 
ATOM   5615 C CD2 . LEU C 3 200 ? 168.080 168.923 86.388  1.00 114.09 ? 200 LEU Q CD2 1 
ATOM   5616 N N   . THR C 3 201 ? 165.754 170.835 90.742  1.00 118.04 ? 201 THR Q N   1 
ATOM   5617 C CA  . THR C 3 201 ? 166.023 172.199 91.172  1.00 119.38 ? 201 THR Q CA  1 
ATOM   5618 C C   . THR C 3 201 ? 167.451 172.598 90.821  1.00 119.74 ? 201 THR Q C   1 
ATOM   5619 O O   . THR C 3 201 ? 168.392 171.818 90.995  1.00 118.56 ? 201 THR Q O   1 
ATOM   5620 C CB  . THR C 3 201 ? 165.790 172.338 92.677  1.00 119.08 ? 201 THR Q CB  1 
ATOM   5621 O OG1 . THR C 3 201 ? 164.520 171.770 93.020  1.00 117.39 ? 201 THR Q OG1 1 
ATOM   5622 C CG2 . THR C 3 201 ? 165.807 173.803 93.089  1.00 119.25 ? 201 THR Q CG2 1 
ATOM   5623 N N   . LEU C 3 202 ? 167.610 173.823 90.327  1.00 128.92 ? 202 LEU Q N   1 
ATOM   5624 C CA  . LEU C 3 202 ? 168.898 174.339 89.895  1.00 128.65 ? 202 LEU Q CA  1 
ATOM   5625 C C   . LEU C 3 202 ? 169.209 175.645 90.614  1.00 128.73 ? 202 LEU Q C   1 
ATOM   5626 O O   . LEU C 3 202 ? 168.317 176.332 91.118  1.00 127.97 ? 202 LEU Q O   1 
ATOM   5627 C CB  . LEU C 3 202 ? 168.928 174.559 88.379  1.00 128.47 ? 202 LEU Q CB  1 
ATOM   5628 C CG  . LEU C 3 202 ? 168.809 173.303 87.518  1.00 128.34 ? 202 LEU Q CG  1 
ATOM   5629 C CD1 . LEU C 3 202 ? 168.926 173.655 86.044  1.00 127.98 ? 202 LEU Q CD1 1 
ATOM   5630 C CD2 . LEU C 3 202 ? 169.863 172.282 87.917  1.00 128.39 ? 202 LEU Q CD2 1 
ATOM   5631 N N   . SER C 3 203 ? 170.496 175.979 90.655  1.00 137.26 ? 203 SER Q N   1 
ATOM   5632 C CA  . SER C 3 203 ? 170.962 177.184 91.323  1.00 138.14 ? 203 SER Q CA  1 
ATOM   5633 C C   . SER C 3 203 ? 170.832 178.383 90.383  1.00 137.31 ? 203 SER Q C   1 
ATOM   5634 O O   . SER C 3 203 ? 170.299 178.282 89.275  1.00 136.69 ? 203 SER Q O   1 
ATOM   5635 C CB  . SER C 3 203 ? 172.396 176.995 91.812  1.00 137.66 ? 203 SER Q CB  1 
ATOM   5636 O OG  . SER C 3 203 ? 172.475 175.945 92.760  1.00 137.41 ? 203 SER Q OG  1 
ATOM   5637 N N   . LYS C 3 204 ? 171.322 179.542 90.830  1.00 141.17 ? 204 LYS Q N   1 
ATOM   5638 C CA  . LYS C 3 204 ? 171.201 180.761 90.036  1.00 141.04 ? 204 LYS Q CA  1 
ATOM   5639 C C   . LYS C 3 204 ? 172.003 180.672 88.743  1.00 141.03 ? 204 LYS Q C   1 
ATOM   5640 O O   . LYS C 3 204 ? 171.536 181.114 87.687  1.00 140.42 ? 204 LYS Q O   1 
ATOM   5641 C CB  . LYS C 3 204 ? 171.646 181.969 90.860  1.00 140.62 ? 204 LYS Q CB  1 
ATOM   5642 N N   . ALA C 3 205 ? 173.210 180.112 88.804  1.00 142.75 ? 205 ALA Q N   1 
ATOM   5643 C CA  . ALA C 3 205 ? 174.096 180.049 87.650  1.00 143.13 ? 205 ALA Q CA  1 
ATOM   5644 C C   . ALA C 3 205 ? 174.180 178.663 87.026  1.00 143.02 ? 205 ALA Q C   1 
ATOM   5645 O O   . ALA C 3 205 ? 174.831 178.508 85.988  1.00 142.52 ? 205 ALA Q O   1 
ATOM   5646 C CB  . ALA C 3 205 ? 175.502 180.521 88.038  1.00 142.77 ? 205 ALA Q CB  1 
ATOM   5647 N N   . ASP C 3 206 ? 173.546 177.654 87.626  1.00 142.11 ? 206 ASP Q N   1 
ATOM   5648 C CA  . ASP C 3 206 ? 173.633 176.302 87.081  1.00 142.47 ? 206 ASP Q CA  1 
ATOM   5649 C C   . ASP C 3 206 ? 172.933 176.199 85.732  1.00 141.98 ? 206 ASP Q C   1 
ATOM   5650 O O   . ASP C 3 206 ? 173.420 175.511 84.826  1.00 141.42 ? 206 ASP Q O   1 
ATOM   5651 C CB  . ASP C 3 206 ? 173.045 175.299 88.072  1.00 142.29 ? 206 ASP Q CB  1 
ATOM   5652 C CG  . ASP C 3 206 ? 173.891 175.152 89.321  1.00 142.66 ? 206 ASP Q CG  1 
ATOM   5653 O OD1 . ASP C 3 206 ? 174.801 175.983 89.526  1.00 141.42 ? 206 ASP Q OD1 1 
ATOM   5654 O OD2 . ASP C 3 206 ? 173.646 174.205 90.099  1.00 142.82 ? 206 ASP Q OD2 1 
ATOM   5655 N N   . TYR C 3 207 ? 171.789 176.870 85.579  1.00 143.20 ? 207 TYR Q N   1 
ATOM   5656 C CA  . TYR C 3 207 ? 171.038 176.784 84.330  1.00 143.78 ? 207 TYR Q CA  1 
ATOM   5657 C C   . TYR C 3 207 ? 171.794 177.413 83.167  1.00 144.66 ? 207 TYR Q C   1 
ATOM   5658 O O   . TYR C 3 207 ? 171.724 176.907 82.041  1.00 143.77 ? 207 TYR Q O   1 
ATOM   5659 C CB  . TYR C 3 207 ? 169.671 177.446 84.494  1.00 143.73 ? 207 TYR Q CB  1 
ATOM   5660 C CG  . TYR C 3 207 ? 168.707 177.156 83.365  1.00 143.72 ? 207 TYR Q CG  1 
ATOM   5661 C CD1 . TYR C 3 207 ? 168.229 175.871 83.146  1.00 143.14 ? 207 TYR Q CD1 1 
ATOM   5662 C CD2 . TYR C 3 207 ? 168.271 178.170 82.522  1.00 143.35 ? 207 TYR Q CD2 1 
ATOM   5663 C CE1 . TYR C 3 207 ? 167.346 175.602 82.117  1.00 143.25 ? 207 TYR Q CE1 1 
ATOM   5664 C CE2 . TYR C 3 207 ? 167.388 177.911 81.490  1.00 143.85 ? 207 TYR Q CE2 1 
ATOM   5665 C CZ  . TYR C 3 207 ? 166.929 176.626 81.292  1.00 144.08 ? 207 TYR Q CZ  1 
ATOM   5666 O OH  . TYR C 3 207 ? 166.050 176.365 80.266  1.00 143.63 ? 207 TYR Q OH  1 
ATOM   5667 N N   . GLU C 3 208 ? 172.508 178.514 83.409  1.00 145.95 ? 208 GLU Q N   1 
ATOM   5668 C CA  . GLU C 3 208 ? 173.258 179.160 82.338  1.00 145.17 ? 208 GLU Q CA  1 
ATOM   5669 C C   . GLU C 3 208 ? 174.538 178.408 81.997  1.00 145.49 ? 208 GLU Q C   1 
ATOM   5670 O O   . GLU C 3 208 ? 174.941 178.384 80.829  1.00 144.92 ? 208 GLU Q O   1 
ATOM   5671 C CB  . GLU C 3 208 ? 173.591 180.604 82.722  1.00 144.42 ? 208 GLU Q CB  1 
ATOM   5672 C CG  . GLU C 3 208 ? 172.385 181.525 82.801  1.00 144.57 ? 208 GLU Q CG  1 
ATOM   5673 C CD  . GLU C 3 208 ? 171.684 181.449 84.142  1.00 145.08 ? 208 GLU Q CD  1 
ATOM   5674 O OE1 . GLU C 3 208 ? 172.165 180.705 85.020  1.00 144.24 ? 208 GLU Q OE1 1 
ATOM   5675 O OE2 . GLU C 3 208 ? 170.653 182.132 84.317  1.00 145.89 ? 208 GLU Q OE2 1 
ATOM   5676 N N   . LYS C 3 209 ? 175.187 177.800 82.993  1.00 146.97 ? 209 LYS Q N   1 
ATOM   5677 C CA  . LYS C 3 209 ? 176.454 177.118 82.748  1.00 146.69 ? 209 LYS Q CA  1 
ATOM   5678 C C   . LYS C 3 209 ? 176.276 175.925 81.815  1.00 146.61 ? 209 LYS Q C   1 
ATOM   5679 O O   . LYS C 3 209 ? 177.098 175.700 80.920  1.00 146.11 ? 209 LYS Q O   1 
ATOM   5680 C CB  . LYS C 3 209 ? 177.075 176.675 84.073  1.00 146.46 ? 209 LYS Q CB  1 
ATOM   5681 C CG  . LYS C 3 209 ? 178.463 176.069 83.937  1.00 146.86 ? 209 LYS Q CG  1 
ATOM   5682 C CD  . LYS C 3 209 ? 178.955 175.505 85.261  1.00 146.76 ? 209 LYS Q CD  1 
ATOM   5683 C CE  . LYS C 3 209 ? 178.943 176.561 86.355  1.00 147.04 ? 209 LYS Q CE  1 
ATOM   5684 N NZ  . LYS C 3 209 ? 179.839 177.707 86.040  1.00 146.70 ? 209 LYS Q NZ  1 
ATOM   5685 N N   . HIS C 3 210 ? 175.212 175.152 82.008  1.00 148.01 ? 210 HIS Q N   1 
ATOM   5686 C CA  . HIS C 3 210 ? 174.947 173.963 81.211  1.00 148.26 ? 210 HIS Q CA  1 
ATOM   5687 C C   . HIS C 3 210 ? 173.695 174.184 80.374  1.00 148.31 ? 210 HIS Q C   1 
ATOM   5688 O O   . HIS C 3 210 ? 172.654 174.588 80.902  1.00 147.97 ? 210 HIS Q O   1 
ATOM   5689 C CB  . HIS C 3 210 ? 174.788 172.735 82.109  1.00 147.80 ? 210 HIS Q CB  1 
ATOM   5690 C CG  . HIS C 3 210 ? 176.041 172.356 82.834  1.00 147.95 ? 210 HIS Q CG  1 
ATOM   5691 N ND1 . HIS C 3 210 ? 176.759 171.218 82.536  1.00 147.35 ? 210 HIS Q ND1 1 
ATOM   5692 C CD2 . HIS C 3 210 ? 176.708 172.967 83.842  1.00 147.92 ? 210 HIS Q CD2 1 
ATOM   5693 C CE1 . HIS C 3 210 ? 177.812 171.143 83.330  1.00 147.66 ? 210 HIS Q CE1 1 
ATOM   5694 N NE2 . HIS C 3 210 ? 177.804 172.192 84.132  1.00 148.02 ? 210 HIS Q NE2 1 
ATOM   5695 N N   . LYS C 3 211 ? 173.796 173.909 79.074  1.00 144.78 ? 211 LYS Q N   1 
ATOM   5696 C CA  . LYS C 3 211 ? 172.743 174.250 78.129  1.00 144.33 ? 211 LYS Q CA  1 
ATOM   5697 C C   . LYS C 3 211 ? 172.058 173.045 77.499  1.00 144.48 ? 211 LYS Q C   1 
ATOM   5698 O O   . LYS C 3 211 ? 171.165 173.231 76.664  1.00 144.07 ? 211 LYS Q O   1 
ATOM   5699 C CB  . LYS C 3 211 ? 173.307 175.149 77.019  1.00 143.37 ? 211 LYS Q CB  1 
ATOM   5700 C CG  . LYS C 3 211 ? 174.181 176.280 77.535  1.00 143.67 ? 211 LYS Q CG  1 
ATOM   5701 C CD  . LYS C 3 211 ? 174.897 176.996 76.403  1.00 144.15 ? 211 LYS Q CD  1 
ATOM   5702 C CE  . LYS C 3 211 ? 175.789 178.106 76.935  1.00 143.89 ? 211 LYS Q CE  1 
ATOM   5703 N NZ  . LYS C 3 211 ? 176.543 178.786 75.847  1.00 144.10 ? 211 LYS Q NZ  1 
ATOM   5704 N N   . VAL C 3 212 ? 172.437 171.825 77.867  1.00 144.96 ? 212 VAL Q N   1 
ATOM   5705 C CA  . VAL C 3 212 ? 171.845 170.614 77.309  1.00 145.18 ? 212 VAL Q CA  1 
ATOM   5706 C C   . VAL C 3 212 ? 171.116 169.881 78.426  1.00 145.11 ? 212 VAL Q C   1 
ATOM   5707 O O   . VAL C 3 212 ? 171.725 169.506 79.435  1.00 144.43 ? 212 VAL Q O   1 
ATOM   5708 C CB  . VAL C 3 212 ? 172.904 169.712 76.657  1.00 144.82 ? 212 VAL Q CB  1 
ATOM   5709 C CG1 . VAL C 3 212 ? 172.238 168.543 75.948  1.00 143.90 ? 212 VAL Q CG1 1 
ATOM   5710 C CG2 . VAL C 3 212 ? 173.763 170.515 75.692  1.00 144.16 ? 212 VAL Q CG2 1 
ATOM   5711 N N   . TYR C 3 213 ? 169.813 169.672 78.242  1.00 141.64 ? 213 TYR Q N   1 
ATOM   5712 C CA  . TYR C 3 213 ? 168.983 168.970 79.209  1.00 140.43 ? 213 TYR Q CA  1 
ATOM   5713 C C   . TYR C 3 213 ? 168.177 167.896 78.497  1.00 140.30 ? 213 TYR Q C   1 
ATOM   5714 O O   . TYR C 3 213 ? 167.630 168.134 77.416  1.00 140.01 ? 213 TYR Q O   1 
ATOM   5715 C CB  . TYR C 3 213 ? 168.038 169.931 79.941  1.00 140.29 ? 213 TYR Q CB  1 
ATOM   5716 C CG  . TYR C 3 213 ? 168.746 170.927 80.828  1.00 141.05 ? 213 TYR Q CG  1 
ATOM   5717 C CD1 . TYR C 3 213 ? 169.132 170.586 82.118  1.00 141.13 ? 213 TYR Q CD1 1 
ATOM   5718 C CD2 . TYR C 3 213 ? 169.029 172.209 80.377  1.00 141.12 ? 213 TYR Q CD2 1 
ATOM   5719 C CE1 . TYR C 3 213 ? 169.781 171.494 82.933  1.00 141.63 ? 213 TYR Q CE1 1 
ATOM   5720 C CE2 . TYR C 3 213 ? 169.677 173.124 81.185  1.00 141.48 ? 213 TYR Q CE2 1 
ATOM   5721 C CZ  . TYR C 3 213 ? 170.051 172.761 82.461  1.00 142.14 ? 213 TYR Q CZ  1 
ATOM   5722 O OH  . TYR C 3 213 ? 170.697 173.669 83.268  1.00 141.26 ? 213 TYR Q OH  1 
ATOM   5723 N N   . ALA C 3 214 ? 168.103 166.716 79.108  1.00 131.10 ? 214 ALA Q N   1 
ATOM   5724 C CA  . ALA C 3 214 ? 167.355 165.598 78.555  1.00 130.79 ? 214 ALA Q CA  1 
ATOM   5725 C C   . ALA C 3 214 ? 166.539 164.957 79.669  1.00 131.23 ? 214 ALA Q C   1 
ATOM   5726 O O   . ALA C 3 214 ? 166.622 165.352 80.836  1.00 130.68 ? 214 ALA Q O   1 
ATOM   5727 C CB  . ALA C 3 214 ? 168.285 164.579 77.888  1.00 130.37 ? 214 ALA Q CB  1 
ATOM   5728 N N   . CYS C 3 215 ? 165.737 163.958 79.299  1.00 130.27 ? 215 CYS Q N   1 
ATOM   5729 C CA  . CYS C 3 215 ? 164.904 163.239 80.266  1.00 129.09 ? 215 CYS Q CA  1 
ATOM   5730 C C   . CYS C 3 215 ? 164.789 161.793 79.783  1.00 129.21 ? 215 CYS Q C   1 
ATOM   5731 O O   . CYS C 3 215 ? 163.927 161.465 78.965  1.00 129.02 ? 215 CYS Q O   1 
ATOM   5732 C CB  . CYS C 3 215 ? 163.538 163.890 80.418  1.00 130.05 ? 215 CYS Q CB  1 
ATOM   5733 S SG  . CYS C 3 215 ? 162.394 162.996 81.493  1.00 132.66 ? 215 CYS Q SG  1 
ATOM   5734 N N   . GLU C 3 216 ? 165.663 160.937 80.306  1.00 127.55 ? 216 GLU Q N   1 
ATOM   5735 C CA  . GLU C 3 216 ? 165.681 159.531 79.930  1.00 128.17 ? 216 GLU Q CA  1 
ATOM   5736 C C   . GLU C 3 216 ? 164.753 158.742 80.843  1.00 127.93 ? 216 GLU Q C   1 
ATOM   5737 O O   . GLU C 3 216 ? 164.866 158.819 82.071  1.00 127.07 ? 216 GLU Q O   1 
ATOM   5738 C CB  . GLU C 3 216 ? 167.100 158.967 80.003  1.00 128.46 ? 216 GLU Q CB  1 
ATOM   5739 C CG  . GLU C 3 216 ? 167.207 157.517 79.557  1.00 128.40 ? 216 GLU Q CG  1 
ATOM   5740 C CD  . GLU C 3 216 ? 168.577 156.924 79.815  1.00 128.79 ? 216 GLU Q CD  1 
ATOM   5741 O OE1 . GLU C 3 216 ? 169.422 157.617 80.421  1.00 129.87 ? 216 GLU Q OE1 1 
ATOM   5742 O OE2 . GLU C 3 216 ? 168.809 155.765 79.413  1.00 127.85 ? 216 GLU Q OE2 1 
ATOM   5743 N N   . VAL C 3 217 ? 163.842 157.984 80.240  1.00 123.28 ? 217 VAL Q N   1 
ATOM   5744 C CA  . VAL C 3 217 ? 162.875 157.170 80.967  1.00 122.47 ? 217 VAL Q CA  1 
ATOM   5745 C C   . VAL C 3 217 ? 163.231 155.708 80.747  1.00 124.54 ? 217 VAL Q C   1 
ATOM   5746 O O   . VAL C 3 217 ? 163.313 155.246 79.602  1.00 124.91 ? 217 VAL Q O   1 
ATOM   5747 C CB  . VAL C 3 217 ? 161.436 157.461 80.517  1.00 121.79 ? 217 VAL Q CB  1 
ATOM   5748 C CG1 . VAL C 3 217 ? 160.456 156.579 81.274  1.00 121.96 ? 217 VAL Q CG1 1 
ATOM   5749 C CG2 . VAL C 3 217 ? 161.108 158.927 80.728  1.00 122.56 ? 217 VAL Q CG2 1 
ATOM   5750 N N   . THR C 3 218 ? 163.440 154.980 81.841  1.00 121.61 ? 218 THR Q N   1 
ATOM   5751 C CA  . THR C 3 218 ? 163.770 153.557 81.798  1.00 120.80 ? 218 THR Q CA  1 
ATOM   5752 C C   . THR C 3 218 ? 162.571 152.692 82.156  1.00 120.61 ? 218 THR Q C   1 
ATOM   5753 O O   . THR C 3 218 ? 162.712 151.665 82.825  1.00 120.36 ? 218 THR Q O   1 
ATOM   5754 C CB  . THR C 3 218 ? 164.944 153.255 82.725  1.00 121.49 ? 218 THR Q CB  1 
ATOM   5755 O OG1 . THR C 3 218 ? 164.588 153.583 84.074  1.00 121.24 ? 218 THR Q OG1 1 
ATOM   5756 C CG2 . THR C 3 218 ? 166.166 154.063 82.317  1.00 120.97 ? 218 THR Q CG2 1 
ATOM   5757 N N   . HIS C 3 219 ? 161.378 153.097 81.728  1.00 118.96 ? 219 HIS Q N   1 
ATOM   5758 C CA  . HIS C 3 219 ? 160.173 152.344 82.045  1.00 119.73 ? 219 HIS Q CA  1 
ATOM   5759 C C   . HIS C 3 219 ? 160.212 150.964 81.404  1.00 117.80 ? 219 HIS Q C   1 
ATOM   5760 O O   . HIS C 3 219 ? 160.609 150.807 80.246  1.00 117.25 ? 219 HIS Q O   1 
ATOM   5761 C CB  . HIS C 3 219 ? 158.933 153.104 81.574  1.00 118.15 ? 219 HIS Q CB  1 
ATOM   5762 C CG  . HIS C 3 219 ? 157.646 152.514 82.058  1.00 117.96 ? 219 HIS Q CG  1 
ATOM   5763 N ND1 . HIS C 3 219 ? 157.415 152.222 83.385  1.00 116.75 ? 219 HIS Q ND1 1 
ATOM   5764 C CD2 . HIS C 3 219 ? 156.525 152.152 81.392  1.00 118.32 ? 219 HIS Q CD2 1 
ATOM   5765 C CE1 . HIS C 3 219 ? 156.204 151.711 83.515  1.00 116.31 ? 219 HIS Q CE1 1 
ATOM   5766 N NE2 . HIS C 3 219 ? 155.643 151.657 82.321  1.00 117.70 ? 219 HIS Q NE2 1 
ATOM   5767 N N   . GLN C 3 220 ? 159.798 149.957 82.169  1.00 118.78 ? 220 GLN Q N   1 
ATOM   5768 C CA  . GLN C 3 220 ? 159.766 148.585 81.684  1.00 119.88 ? 220 GLN Q CA  1 
ATOM   5769 C C   . GLN C 3 220 ? 158.488 148.250 80.929  1.00 120.05 ? 220 GLN Q C   1 
ATOM   5770 O O   . GLN C 3 220 ? 158.413 147.179 80.317  1.00 119.81 ? 220 GLN Q O   1 
ATOM   5771 C CB  . GLN C 3 220 ? 159.937 147.609 82.853  1.00 119.54 ? 220 GLN Q CB  1 
ATOM   5772 N N   . GLY C 3 221 ? 157.487 149.131 80.953  1.00 120.26 ? 221 GLY Q N   1 
ATOM   5773 C CA  . GLY C 3 221 ? 156.241 148.855 80.263  1.00 119.52 ? 221 GLY Q CA  1 
ATOM   5774 C C   . GLY C 3 221 ? 156.329 148.962 78.757  1.00 120.94 ? 221 GLY Q C   1 
ATOM   5775 O O   . GLY C 3 221 ? 155.514 148.354 78.056  1.00 120.44 ? 221 GLY Q O   1 
ATOM   5776 N N   . LEU C 3 222 ? 157.298 149.714 78.243  1.00 126.34 ? 222 LEU Q N   1 
ATOM   5777 C CA  . LEU C 3 222 ? 157.467 149.899 76.811  1.00 126.12 ? 222 LEU Q CA  1 
ATOM   5778 C C   . LEU C 3 222 ? 158.756 149.234 76.342  1.00 126.69 ? 222 LEU Q C   1 
ATOM   5779 O O   . LEU C 3 222 ? 159.622 148.870 77.142  1.00 125.98 ? 222 LEU Q O   1 
ATOM   5780 C CB  . LEU C 3 222 ? 157.461 151.387 76.442  1.00 124.82 ? 222 LEU Q CB  1 
ATOM   5781 C CG  . LEU C 3 222 ? 158.766 152.179 76.505  1.00 125.88 ? 222 LEU Q CG  1 
ATOM   5782 C CD1 . LEU C 3 222 ? 158.635 153.449 75.682  1.00 124.94 ? 222 LEU Q CD1 1 
ATOM   5783 C CD2 . LEU C 3 222 ? 159.130 152.511 77.940  1.00 125.10 ? 222 LEU Q CD2 1 
ATOM   5784 N N   . SER C 3 223 ? 158.864 149.073 75.021  1.00 127.90 ? 223 SER Q N   1 
ATOM   5785 C CA  . SER C 3 223 ? 159.924 148.245 74.450  1.00 127.73 ? 223 SER Q CA  1 
ATOM   5786 C C   . SER C 3 223 ? 161.304 148.851 74.677  1.00 127.42 ? 223 SER Q C   1 
ATOM   5787 O O   . SER C 3 223 ? 162.218 148.173 75.160  1.00 127.35 ? 223 SER Q O   1 
ATOM   5788 C CB  . SER C 3 223 ? 159.670 148.034 72.957  1.00 126.93 ? 223 SER Q CB  1 
ATOM   5789 O OG  . SER C 3 223 ? 159.662 149.268 72.262  1.00 127.60 ? 223 SER Q OG  1 
ATOM   5790 N N   . SER C 3 224 ? 161.477 150.125 74.340  1.00 127.96 ? 224 SER Q N   1 
ATOM   5791 C CA  . SER C 3 224 ? 162.792 150.743 74.369  1.00 128.27 ? 224 SER Q CA  1 
ATOM   5792 C C   . SER C 3 224 ? 162.757 152.031 75.176  1.00 128.71 ? 224 SER Q C   1 
ATOM   5793 O O   . SER C 3 224 ? 161.724 152.704 75.234  1.00 129.45 ? 224 SER Q O   1 
ATOM   5794 C CB  . SER C 3 224 ? 163.289 151.044 72.947  1.00 127.74 ? 224 SER Q CB  1 
ATOM   5795 O OG  . SER C 3 224 ? 162.359 151.848 72.242  1.00 126.50 ? 224 SER Q OG  1 
ATOM   5796 N N   . PRO C 3 225 ? 163.871 152.395 75.813  1.00 131.88 ? 225 PRO Q N   1 
ATOM   5797 C CA  . PRO C 3 225 ? 163.902 153.643 76.585  1.00 131.19 ? 225 PRO Q CA  1 
ATOM   5798 C C   . PRO C 3 225 ? 163.646 154.854 75.701  1.00 130.88 ? 225 PRO Q C   1 
ATOM   5799 O O   . PRO C 3 225 ? 164.094 154.918 74.554  1.00 130.16 ? 225 PRO Q O   1 
ATOM   5800 C CB  . PRO C 3 225 ? 165.318 153.663 77.172  1.00 130.91 ? 225 PRO Q CB  1 
ATOM   5801 C CG  . PRO C 3 225 ? 165.765 152.238 77.148  1.00 131.33 ? 225 PRO Q CG  1 
ATOM   5802 C CD  . PRO C 3 225 ? 165.129 151.638 75.933  1.00 130.74 ? 225 PRO Q CD  1 
ATOM   5803 N N   . VAL C 3 226 ? 162.920 155.823 76.251  1.00 129.44 ? 226 VAL Q N   1 
ATOM   5804 C CA  . VAL C 3 226 ? 162.569 157.051 75.549  1.00 129.35 ? 226 VAL Q CA  1 
ATOM   5805 C C   . VAL C 3 226 ? 163.211 158.218 76.284  1.00 128.89 ? 226 VAL Q C   1 
ATOM   5806 O O   . VAL C 3 226 ? 163.034 158.366 77.499  1.00 127.59 ? 226 VAL Q O   1 
ATOM   5807 C CB  . VAL C 3 226 ? 161.043 157.235 75.450  1.00 128.28 ? 226 VAL Q CB  1 
ATOM   5808 C CG1 . VAL C 3 226 ? 160.697 158.692 75.189  1.00 128.28 ? 226 VAL Q CG1 1 
ATOM   5809 C CG2 . VAL C 3 226 ? 160.471 156.344 74.359  1.00 127.34 ? 226 VAL Q CG2 1 
ATOM   5810 N N   . THR C 3 227 ? 163.959 159.036 75.550  1.00 129.07 ? 227 THR Q N   1 
ATOM   5811 C CA  . THR C 3 227 ? 164.623 160.208 76.100  1.00 129.06 ? 227 THR Q CA  1 
ATOM   5812 C C   . THR C 3 227 ? 164.100 161.453 75.400  1.00 128.87 ? 227 THR Q C   1 
ATOM   5813 O O   . THR C 3 227 ? 164.086 161.516 74.166  1.00 128.07 ? 227 THR Q O   1 
ATOM   5814 C CB  . THR C 3 227 ? 166.143 160.110 75.943  1.00 128.92 ? 227 THR Q CB  1 
ATOM   5815 O OG1 . THR C 3 227 ? 166.622 158.940 76.618  1.00 128.53 ? 227 THR Q OG1 1 
ATOM   5816 C CG2 . THR C 3 227 ? 166.822 161.341 76.528  1.00 128.67 ? 227 THR Q CG2 1 
ATOM   5817 N N   . LYS C 3 228 ? 163.665 162.433 76.186  1.00 128.23 ? 228 LYS Q N   1 
ATOM   5818 C CA  . LYS C 3 228 ? 163.200 163.716 75.674  1.00 128.31 ? 228 LYS Q CA  1 
ATOM   5819 C C   . LYS C 3 228 ? 164.212 164.783 76.065  1.00 128.35 ? 228 LYS Q C   1 
ATOM   5820 O O   . LYS C 3 228 ? 164.483 164.979 77.255  1.00 128.10 ? 228 LYS Q O   1 
ATOM   5821 C CB  . LYS C 3 228 ? 161.813 164.055 76.217  1.00 127.10 ? 228 LYS Q CB  1 
ATOM   5822 C CG  . LYS C 3 228 ? 160.958 164.869 75.262  1.00 127.47 ? 228 LYS Q CG  1 
ATOM   5823 C CD  . LYS C 3 228 ? 160.575 164.053 74.038  1.00 127.99 ? 228 LYS Q CD  1 
ATOM   5824 C CE  . LYS C 3 228 ? 159.778 162.819 74.425  1.00 127.41 ? 228 LYS Q CE  1 
ATOM   5825 N NZ  . LYS C 3 228 ? 159.496 161.956 73.247  1.00 127.57 ? 228 LYS Q NZ  1 
ATOM   5826 N N   . SER C 3 229 ? 164.763 165.470 75.069  1.00 133.05 ? 229 SER Q N   1 
ATOM   5827 C CA  . SER C 3 229 ? 165.832 166.433 75.273  1.00 133.20 ? 229 SER Q CA  1 
ATOM   5828 C C   . SER C 3 229 ? 165.319 167.856 75.098  1.00 133.11 ? 229 SER Q C   1 
ATOM   5829 O O   . SER C 3 229 ? 164.270 168.097 74.494  1.00 132.57 ? 229 SER Q O   1 
ATOM   5830 C CB  . SER C 3 229 ? 166.991 166.176 74.303  1.00 133.43 ? 229 SER Q CB  1 
ATOM   5831 O OG  . SER C 3 229 ? 167.446 164.837 74.395  1.00 133.00 ? 229 SER Q OG  1 
ATOM   5832 N N   . PHE C 3 230 ? 166.083 168.802 75.641  1.00 138.37 ? 230 PHE Q N   1 
ATOM   5833 C CA  . PHE C 3 230 ? 165.763 170.217 75.522  1.00 139.09 ? 230 PHE Q CA  1 
ATOM   5834 C C   . PHE C 3 230 ? 167.054 171.020 75.558  1.00 139.53 ? 230 PHE Q C   1 
ATOM   5835 O O   . PHE C 3 230 ? 168.079 170.565 76.074  1.00 138.48 ? 230 PHE Q O   1 
ATOM   5836 C CB  . PHE C 3 230 ? 164.812 170.678 76.632  1.00 138.03 ? 230 PHE Q CB  1 
ATOM   5837 N N   . ASN C 3 231 ? 166.992 172.228 75.003  1.00 142.17 ? 231 ASN Q N   1 
ATOM   5838 C CA  . ASN C 3 231 ? 168.143 173.116 74.949  1.00 141.47 ? 231 ASN Q CA  1 
ATOM   5839 C C   . ASN C 3 231 ? 167.689 174.543 75.215  1.00 141.02 ? 231 ASN Q C   1 
ATOM   5840 O O   . ASN C 3 231 ? 166.520 174.890 75.033  1.00 140.75 ? 231 ASN Q O   1 
ATOM   5841 C CB  . ASN C 3 231 ? 168.862 173.032 73.596  1.00 140.99 ? 231 ASN Q CB  1 
ATOM   5842 C CG  . ASN C 3 231 ? 169.414 171.651 73.316  1.00 140.40 ? 231 ASN Q CG  1 
ATOM   5843 O OD1 . ASN C 3 231 ? 168.770 170.835 72.659  1.00 140.25 ? 231 ASN Q OD1 1 
ATOM   5844 N ND2 . ASN C 3 231 ? 170.613 171.379 73.818  1.00 140.23 ? 231 ASN Q ND2 1 
ATOM   5845 N N   . ARG C 3 232 ? 168.634 175.368 75.655  1.00 143.11 ? 232 ARG Q N   1 
ATOM   5846 C CA  . ARG C 3 232 ? 168.339 176.768 75.923  1.00 143.09 ? 232 ARG Q CA  1 
ATOM   5847 C C   . ARG C 3 232 ? 167.995 177.496 74.629  1.00 143.24 ? 232 ARG Q C   1 
ATOM   5848 O O   . ARG C 3 232 ? 168.635 177.294 73.593  1.00 142.72 ? 232 ARG Q O   1 
ATOM   5849 C CB  . ARG C 3 232 ? 169.527 177.439 76.608  1.00 142.75 ? 232 ARG Q CB  1 
ATOM   5850 C CG  . ARG C 3 232 ? 169.727 177.013 78.052  1.00 142.68 ? 232 ARG Q CG  1 
ATOM   5851 C CD  . ARG C 3 232 ? 170.966 177.659 78.647  1.00 143.21 ? 232 ARG Q CD  1 
ATOM   5852 N NE  . ARG C 3 232 ? 171.112 179.045 78.218  1.00 143.26 ? 232 ARG Q NE  1 
ATOM   5853 C CZ  . ARG C 3 232 ? 170.491 180.072 78.780  1.00 142.79 ? 232 ARG Q CZ  1 
ATOM   5854 N NH1 . ARG C 3 232 ? 169.668 179.907 79.803  1.00 142.75 ? 232 ARG Q NH1 1 
ATOM   5855 N NH2 . ARG C 3 232 ? 170.699 181.296 78.302  1.00 142.47 ? 232 ARG Q NH2 1 
ATOM   5856 N N   . GLY C 3 233 ? 166.978 178.352 74.697  1.00 145.23 ? 233 GLY Q N   1 
ATOM   5857 C CA  . GLY C 3 233 ? 166.487 179.052 73.531  1.00 145.42 ? 233 GLY Q CA  1 
ATOM   5858 C C   . GLY C 3 233 ? 165.473 178.290 72.708  1.00 145.52 ? 233 GLY Q C   1 
ATOM   5859 O O   . GLY C 3 233 ? 164.966 178.836 71.719  1.00 144.65 ? 233 GLY Q O   1 
ATOM   5860 N N   . GLU C 3 234 ? 165.159 177.052 73.080  1.00 144.05 ? 234 GLU Q N   1 
ATOM   5861 C CA  . GLU C 3 234 ? 164.178 176.248 72.366  1.00 143.53 ? 234 GLU Q CA  1 
ATOM   5862 C C   . GLU C 3 234 ? 162.797 176.469 72.969  1.00 143.95 ? 234 GLU Q C   1 
ATOM   5863 O O   . GLU C 3 234 ? 162.633 176.424 74.193  1.00 143.28 ? 234 GLU Q O   1 
ATOM   5864 C CB  . GLU C 3 234 ? 164.550 174.766 72.424  1.00 142.56 ? 234 GLU Q CB  1 
ATOM   5865 C CG  . GLU C 3 234 ? 163.579 173.848 71.701  1.00 142.48 ? 234 GLU Q CG  1 
ATOM   5866 C CD  . GLU C 3 234 ? 163.797 172.387 72.043  1.00 142.85 ? 234 GLU Q CD  1 
ATOM   5867 O OE1 . GLU C 3 234 ? 164.634 172.101 72.924  1.00 142.44 ? 234 GLU Q OE1 1 
ATOM   5868 O OE2 . GLU C 3 234 ? 163.132 171.526 71.431  1.00 143.53 ? 234 GLU Q OE2 1 
ATOM   5869 N N   . CYS C 3 235 ? 161.812 176.708 72.110  1.00 142.71 ? 235 CYS Q N   1 
ATOM   5870 C CA  . CYS C 3 235 ? 160.441 176.924 72.558  1.00 142.22 ? 235 CYS Q CA  1 
ATOM   5871 C C   . CYS C 3 235 ? 159.838 175.635 73.108  1.00 141.92 ? 235 CYS Q C   1 
ATOM   5872 O O   . CYS C 3 235 ? 160.316 174.539 72.818  1.00 141.72 ? 235 CYS Q O   1 
ATOM   5873 C CB  . CYS C 3 235 ? 159.582 177.464 71.413  1.00 140.95 ? 235 CYS Q CB  1 
ATOM   5874 S SG  . CYS C 3 235 ? 160.154 179.033 70.722  1.00 142.71 ? 235 CYS Q SG  1 
ATOM   5875 O OXT . CYS C 3 235 ? 158.859 175.660 73.855  1.00 141.21 ? 235 CYS Q OXT 1 
ATOM   5876 N N   . VAL D 4 192 ? 162.734 167.389 202.205 1.00 112.94 ? 56  VAL R N   1 
ATOM   5877 C CA  . VAL D 4 192 ? 163.025 166.438 201.140 1.00 113.02 ? 56  VAL R CA  1 
ATOM   5878 C C   . VAL D 4 192 ? 164.390 166.728 200.529 1.00 112.90 ? 56  VAL R C   1 
ATOM   5879 O O   . VAL D 4 192 ? 164.490 167.399 199.502 1.00 113.31 ? 56  VAL R O   1 
ATOM   5880 C CB  . VAL D 4 192 ? 161.931 166.460 200.059 1.00 112.35 ? 56  VAL R CB  1 
ATOM   5881 N N   . ASN D 4 193 ? 165.440 166.220 201.166 1.00 112.24 ? 57  ASN R N   1 
ATOM   5882 C CA  . ASN D 4 193 ? 166.801 166.395 200.678 1.00 112.29 ? 57  ASN R CA  1 
ATOM   5883 C C   . ASN D 4 193 ? 167.142 165.280 199.698 1.00 113.33 ? 57  ASN R C   1 
ATOM   5884 O O   . ASN D 4 193 ? 167.036 164.096 200.033 1.00 112.86 ? 57  ASN R O   1 
ATOM   5885 C CB  . ASN D 4 193 ? 167.795 166.406 201.839 1.00 111.26 ? 57  ASN R CB  1 
ATOM   5886 N N   . THR D 4 194 ? 167.553 165.663 198.492 1.00 113.18 ? 58  THR R N   1 
ATOM   5887 C CA  . THR D 4 194 ? 167.896 164.700 197.457 1.00 112.68 ? 58  THR R CA  1 
ATOM   5888 C C   . THR D 4 194 ? 169.042 165.254 196.625 1.00 112.98 ? 58  THR R C   1 
ATOM   5889 O O   . THR D 4 194 ? 169.292 166.462 196.602 1.00 111.23 ? 58  THR R O   1 
ATOM   5890 C CB  . THR D 4 194 ? 166.695 164.376 196.560 1.00 111.39 ? 58  THR R CB  1 
ATOM   5891 N N   . ASP D 4 195 ? 169.740 164.351 195.942 1.00 117.04 ? 59  ASP R N   1 
ATOM   5892 C CA  . ASP D 4 195 ? 170.864 164.747 195.105 1.00 117.23 ? 59  ASP R CA  1 
ATOM   5893 C C   . ASP D 4 195 ? 170.390 165.616 193.947 1.00 116.96 ? 59  ASP R C   1 
ATOM   5894 O O   . ASP D 4 195 ? 169.390 165.314 193.288 1.00 115.93 ? 59  ASP R O   1 
ATOM   5895 C CB  . ASP D 4 195 ? 171.591 163.513 194.573 1.00 115.52 ? 59  ASP R CB  1 
ATOM   5896 N N   . ILE D 4 196 ? 171.117 166.707 193.703 1.00 113.47 ? 60  ILE R N   1 
ATOM   5897 C CA  . ILE D 4 196 ? 170.745 167.628 192.633 1.00 113.14 ? 60  ILE R CA  1 
ATOM   5898 C C   . ILE D 4 196 ? 170.965 166.983 191.270 1.00 114.24 ? 60  ILE R C   1 
ATOM   5899 O O   . ILE D 4 196 ? 170.118 167.080 190.375 1.00 114.24 ? 60  ILE R O   1 
ATOM   5900 C CB  . ILE D 4 196 ? 171.527 168.947 192.766 1.00 112.54 ? 60  ILE R CB  1 
ATOM   5901 N N   . TYR D 4 197 ? 172.111 166.321 191.089 1.00 116.99 ? 61  TYR R N   1 
ATOM   5902 C CA  . TYR D 4 197 ? 172.397 165.672 189.813 1.00 117.59 ? 61  TYR R CA  1 
ATOM   5903 C C   . TYR D 4 197 ? 171.422 164.534 189.538 1.00 118.55 ? 61  TYR R C   1 
ATOM   5904 O O   . TYR D 4 197 ? 170.960 164.363 188.402 1.00 117.85 ? 61  TYR R O   1 
ATOM   5905 C CB  . TYR D 4 197 ? 173.839 165.163 189.795 1.00 115.83 ? 61  TYR R CB  1 
ATOM   5906 N N   . SER D 4 198 ? 171.099 163.745 190.566 1.00 117.02 ? 62  SER R N   1 
ATOM   5907 C CA  . SER D 4 198 ? 170.160 162.643 190.390 1.00 115.61 ? 62  SER R CA  1 
ATOM   5908 C C   . SER D 4 198 ? 168.780 163.151 189.994 1.00 114.79 ? 62  SER R C   1 
ATOM   5909 O O   . SER D 4 198 ? 168.100 162.536 189.166 1.00 113.68 ? 62  SER R O   1 
ATOM   5910 C CB  . SER D 4 198 ? 170.081 161.812 191.670 1.00 115.20 ? 62  SER R CB  1 
ATOM   5911 N N   . LYS D 4 199 ? 168.345 164.269 190.584 1.00 115.06 ? 63  LYS R N   1 
ATOM   5912 C CA  . LYS D 4 199 ? 167.054 164.846 190.222 1.00 115.06 ? 63  LYS R CA  1 
ATOM   5913 C C   . LYS D 4 199 ? 167.032 165.279 188.761 1.00 115.60 ? 63  LYS R C   1 
ATOM   5914 O O   . LYS D 4 199 ? 166.050 165.041 188.047 1.00 115.28 ? 63  LYS R O   1 
ATOM   5915 C CB  . LYS D 4 199 ? 166.731 166.026 191.138 1.00 114.27 ? 63  LYS R CB  1 
ATOM   5916 N N   . VAL D 4 200 ? 168.110 165.912 188.295 1.00 114.32 ? 64  VAL R N   1 
ATOM   5917 C CA  . VAL D 4 200 ? 168.185 166.309 186.892 1.00 113.85 ? 64  VAL R CA  1 
ATOM   5918 C C   . VAL D 4 200 ? 168.152 165.081 185.992 1.00 114.49 ? 64  VAL R C   1 
ATOM   5919 O O   . VAL D 4 200 ? 167.480 165.072 184.952 1.00 113.77 ? 64  VAL R O   1 
ATOM   5920 C CB  . VAL D 4 200 ? 169.443 167.161 186.642 1.00 113.86 ? 64  VAL R CB  1 
ATOM   5921 N N   . LEU D 4 201 ? 168.875 164.026 186.379 1.00 117.08 ? 65  LEU R N   1 
ATOM   5922 C CA  . LEU D 4 201 ? 168.901 162.810 185.570 1.00 117.87 ? 65  LEU R CA  1 
ATOM   5923 C C   . LEU D 4 201 ? 167.521 162.169 185.477 1.00 116.79 ? 65  LEU R C   1 
ATOM   5924 O O   . LEU D 4 201 ? 167.089 161.763 184.390 1.00 114.85 ? 65  LEU R O   1 
ATOM   5925 C CB  . LEU D 4 201 ? 169.914 161.820 186.145 1.00 116.78 ? 65  LEU R CB  1 
ATOM   5926 N N   . VAL D 4 202 ? 166.812 162.068 186.605 1.00 115.05 ? 66  VAL R N   1 
ATOM   5927 C CA  . VAL D 4 202 ? 165.499 161.430 186.577 1.00 113.57 ? 66  VAL R CA  1 
ATOM   5928 C C   . VAL D 4 202 ? 164.507 162.299 185.812 1.00 113.06 ? 66  VAL R C   1 
ATOM   5929 O O   . VAL D 4 202 ? 163.638 161.785 185.103 1.00 111.76 ? 66  VAL R O   1 
ATOM   5930 C CB  . VAL D 4 202 ? 165.001 161.100 187.999 1.00 112.59 ? 66  VAL R CB  1 
ATOM   5931 C CG1 . VAL D 4 202 ? 165.033 162.305 188.897 1.00 112.36 ? 66  VAL R CG1 1 
ATOM   5932 C CG2 . VAL D 4 202 ? 163.607 160.510 187.964 1.00 111.76 ? 66  VAL R CG2 1 
ATOM   5933 N N   . THR D 4 203 ? 164.623 163.626 185.923 1.00 113.81 ? 67  THR R N   1 
ATOM   5934 C CA  . THR D 4 203 ? 163.747 164.497 185.143 1.00 114.41 ? 67  THR R CA  1 
ATOM   5935 C C   . THR D 4 203 ? 163.989 164.330 183.646 1.00 114.44 ? 67  THR R C   1 
ATOM   5936 O O   . THR D 4 203 ? 163.037 164.251 182.857 1.00 114.09 ? 67  THR R O   1 
ATOM   5937 C CB  . THR D 4 203 ? 163.948 165.954 185.557 1.00 115.64 ? 67  THR R CB  1 
ATOM   5938 O OG1 . THR D 4 203 ? 163.807 166.073 186.978 1.00 116.05 ? 67  THR R OG1 1 
ATOM   5939 C CG2 . THR D 4 203 ? 162.922 166.845 184.876 1.00 114.46 ? 67  THR R CG2 1 
ATOM   5940 N N   . ALA D 4 204 ? 165.259 164.266 183.238 1.00 111.70 ? 68  ALA R N   1 
ATOM   5941 C CA  . ALA D 4 204 ? 165.568 164.074 181.825 1.00 111.50 ? 68  ALA R CA  1 
ATOM   5942 C C   . ALA D 4 204 ? 165.055 162.728 181.326 1.00 111.64 ? 68  ALA R C   1 
ATOM   5943 O O   . ALA D 4 204 ? 164.487 162.637 180.229 1.00 110.99 ? 68  ALA R O   1 
ATOM   5944 C CB  . ALA D 4 204 ? 167.074 164.198 181.598 1.00 111.57 ? 68  ALA R CB  1 
ATOM   5945 N N   . VAL D 4 205 ? 165.231 161.670 182.122 1.00 107.97 ? 69  VAL R N   1 
ATOM   5946 C CA  . VAL D 4 205 ? 164.746 160.363 181.692 1.00 107.20 ? 69  VAL R CA  1 
ATOM   5947 C C   . VAL D 4 205 ? 163.222 160.338 181.665 1.00 107.24 ? 69  VAL R C   1 
ATOM   5948 O O   . VAL D 4 205 ? 162.624 159.673 180.817 1.00 105.64 ? 69  VAL R O   1 
ATOM   5949 C CB  . VAL D 4 205 ? 165.329 159.237 182.570 1.00 107.65 ? 69  VAL R CB  1 
ATOM   5950 C CG1 . VAL D 4 205 ? 164.540 159.064 183.856 1.00 107.27 ? 69  VAL R CG1 1 
ATOM   5951 C CG2 . VAL D 4 205 ? 165.390 157.936 181.782 1.00 106.78 ? 69  VAL R CG2 1 
ATOM   5952 N N   . TYR D 4 206 ? 162.563 161.073 182.562 1.00 105.19 ? 70  TYR R N   1 
ATOM   5953 C CA  . TYR D 4 206 ? 161.107 161.133 182.533 1.00 104.24 ? 70  TYR R CA  1 
ATOM   5954 C C   . TYR D 4 206 ? 160.619 161.841 181.280 1.00 104.08 ? 70  TYR R C   1 
ATOM   5955 O O   . TYR D 4 206 ? 159.628 161.427 180.674 1.00 104.16 ? 70  TYR R O   1 
ATOM   5956 C CB  . TYR D 4 206 ? 160.585 161.829 183.787 1.00 104.89 ? 70  TYR R CB  1 
ATOM   5957 C CG  . TYR D 4 206 ? 160.377 160.888 184.948 1.00 104.90 ? 70  TYR R CG  1 
ATOM   5958 C CD1 . TYR D 4 206 ? 161.264 159.851 185.183 1.00 104.14 ? 70  TYR R CD1 1 
ATOM   5959 C CD2 . TYR D 4 206 ? 159.313 161.051 185.825 1.00 104.47 ? 70  TYR R CD2 1 
ATOM   5960 C CE1 . TYR D 4 206 ? 161.089 158.991 186.236 1.00 104.34 ? 70  TYR R CE1 1 
ATOM   5961 C CE2 . TYR D 4 206 ? 159.132 160.192 186.890 1.00 103.40 ? 70  TYR R CE2 1 
ATOM   5962 C CZ  . TYR D 4 206 ? 160.028 159.165 187.088 1.00 103.84 ? 70  TYR R CZ  1 
ATOM   5963 O OH  . TYR D 4 206 ? 159.863 158.305 188.143 1.00 104.94 ? 70  TYR R OH  1 
ATOM   5964 N N   . LEU D 4 207 ? 161.309 162.907 180.873 1.00 103.85 ? 71  LEU R N   1 
ATOM   5965 C CA  . LEU D 4 207 ? 160.973 163.553 179.606 1.00 103.81 ? 71  LEU R CA  1 
ATOM   5966 C C   . LEU D 4 207 ? 161.201 162.606 178.431 1.00 104.54 ? 71  LEU R C   1 
ATOM   5967 O O   . LEU D 4 207 ? 160.418 162.593 177.470 1.00 103.45 ? 71  LEU R O   1 
ATOM   5968 C CB  . LEU D 4 207 ? 161.788 164.834 179.439 1.00 103.28 ? 71  LEU R CB  1 
ATOM   5969 C CG  . LEU D 4 207 ? 161.047 166.145 179.716 1.00 103.26 ? 71  LEU R CG  1 
ATOM   5970 C CD1 . LEU D 4 207 ? 159.836 166.285 178.806 1.00 103.35 ? 71  LEU R CD1 1 
ATOM   5971 C CD2 . LEU D 4 207 ? 160.633 166.236 181.178 1.00 103.19 ? 71  LEU R CD2 1 
ATOM   5972 N N   . ALA D 4 208 ? 162.273 161.811 178.489 1.00 106.38 ? 72  ALA R N   1 
ATOM   5973 C CA  . ALA D 4 208 ? 162.538 160.848 177.424 1.00 105.43 ? 72  ALA R CA  1 
ATOM   5974 C C   . ALA D 4 208 ? 161.429 159.806 177.326 1.00 105.57 ? 72  ALA R C   1 
ATOM   5975 O O   . ALA D 4 208 ? 160.955 159.489 176.228 1.00 105.83 ? 72  ALA R O   1 
ATOM   5976 C CB  . ALA D 4 208 ? 163.891 160.177 177.653 1.00 104.67 ? 72  ALA R CB  1 
ATOM   5977 N N   . LEU D 4 209 ? 161.001 159.258 178.464 1.00 102.34 ? 73  LEU R N   1 
ATOM   5978 C CA  . LEU D 4 209 ? 159.870 158.335 178.448 1.00 101.59 ? 73  LEU R CA  1 
ATOM   5979 C C   . LEU D 4 209 ? 158.597 159.029 177.988 1.00 100.27 ? 73  LEU R C   1 
ATOM   5980 O O   . LEU D 4 209 ? 157.780 158.426 177.287 1.00 99.72  ? 73  LEU R O   1 
ATOM   5981 C CB  . LEU D 4 209 ? 159.674 157.679 179.817 1.00 100.42 ? 73  LEU R CB  1 
ATOM   5982 C CG  . LEU D 4 209 ? 160.570 156.501 180.225 1.00 100.04 ? 73  LEU R CG  1 
ATOM   5983 C CD1 . LEU D 4 209 ? 162.046 156.813 180.240 1.00 99.89  ? 73  LEU R CD1 1 
ATOM   5984 C CD2 . LEU D 4 209 ? 160.134 155.982 181.588 1.00 100.73 ? 73  LEU R CD2 1 
ATOM   5985 N N   . PHE D 4 210 ? 158.414 160.299 178.355 1.00 98.67  ? 74  PHE R N   1 
ATOM   5986 C CA  . PHE D 4 210 ? 157.245 161.035 177.889 1.00 99.39  ? 74  PHE R CA  1 
ATOM   5987 C C   . PHE D 4 210 ? 157.207 161.039 176.367 1.00 99.42  ? 74  PHE R C   1 
ATOM   5988 O O   . PHE D 4 210 ? 156.219 160.611 175.758 1.00 99.71  ? 74  PHE R O   1 
ATOM   5989 C CB  . PHE D 4 210 ? 157.277 162.466 178.447 1.00 99.01  ? 74  PHE R CB  1 
ATOM   5990 C CG  . PHE D 4 210 ? 156.024 163.298 178.181 1.00 98.61  ? 74  PHE R CG  1 
ATOM   5991 C CD1 . PHE D 4 210 ? 155.138 163.003 177.154 1.00 98.82  ? 74  PHE R CD1 1 
ATOM   5992 C CD2 . PHE D 4 210 ? 155.755 164.398 178.976 1.00 99.47  ? 74  PHE R CD2 1 
ATOM   5993 C CE1 . PHE D 4 210 ? 154.018 163.774 176.935 1.00 98.71  ? 74  PHE R CE1 1 
ATOM   5994 C CE2 . PHE D 4 210 ? 154.633 165.174 178.761 1.00 100.10 ? 74  PHE R CE2 1 
ATOM   5995 C CZ  . PHE D 4 210 ? 153.765 164.860 177.740 1.00 100.31 ? 74  PHE R CZ  1 
ATOM   5996 N N   . VAL D 4 211 ? 158.293 161.488 175.737 1.00 99.45  ? 75  VAL R N   1 
ATOM   5997 C CA  . VAL D 4 211 ? 158.281 161.606 174.281 1.00 100.09 ? 75  VAL R CA  1 
ATOM   5998 C C   . VAL D 4 211 ? 158.172 160.228 173.633 1.00 99.34  ? 75  VAL R C   1 
ATOM   5999 O O   . VAL D 4 211 ? 157.395 160.037 172.688 1.00 97.89  ? 75  VAL R O   1 
ATOM   6000 C CB  . VAL D 4 211 ? 159.507 162.395 173.777 1.00 99.37  ? 75  VAL R CB  1 
ATOM   6001 C CG1 . VAL D 4 211 ? 160.802 161.825 174.317 1.00 98.54  ? 75  VAL R CG1 1 
ATOM   6002 C CG2 . VAL D 4 211 ? 159.530 162.421 172.257 1.00 98.81  ? 75  VAL R CG2 1 
ATOM   6003 N N   . VAL D 4 212 ? 158.906 159.239 174.153 1.00 97.34  ? 76  VAL R N   1 
ATOM   6004 C CA  . VAL D 4 212 ? 158.891 157.906 173.553 1.00 97.40  ? 76  VAL R CA  1 
ATOM   6005 C C   . VAL D 4 212 ? 157.496 157.296 173.627 1.00 97.92  ? 76  VAL R C   1 
ATOM   6006 O O   . VAL D 4 212 ? 156.960 156.817 172.621 1.00 93.92  ? 76  VAL R O   1 
ATOM   6007 C CB  . VAL D 4 212 ? 159.936 157.002 174.231 1.00 95.90  ? 76  VAL R CB  1 
ATOM   6008 N N   . GLY D 4 213 ? 156.889 157.304 174.814 1.00 100.99 ? 77  GLY R N   1 
ATOM   6009 C CA  . GLY D 4 213 ? 155.568 156.747 175.011 1.00 99.32  ? 77  GLY R CA  1 
ATOM   6010 C C   . GLY D 4 213 ? 154.491 157.464 174.230 1.00 98.68  ? 77  GLY R C   1 
ATOM   6011 O O   . GLY D 4 213 ? 153.636 156.816 173.620 1.00 98.42  ? 77  GLY R O   1 
ATOM   6012 N N   . THR D 4 214 ? 154.517 158.801 174.233 1.00 95.82  ? 78  THR R N   1 
ATOM   6013 C CA  . THR D 4 214 ? 153.530 159.548 173.465 1.00 96.19  ? 78  THR R CA  1 
ATOM   6014 C C   . THR D 4 214 ? 153.648 159.260 171.975 1.00 96.55  ? 78  THR R C   1 
ATOM   6015 O O   . THR D 4 214 ? 152.631 159.023 171.314 1.00 95.17  ? 78  THR R O   1 
ATOM   6016 C CB  . THR D 4 214 ? 153.678 161.046 173.727 1.00 95.36  ? 78  THR R CB  1 
ATOM   6017 N N   . VAL D 4 215 ? 154.870 159.250 171.436 1.00 96.89  ? 79  VAL R N   1 
ATOM   6018 C CA  . VAL D 4 215 ? 155.056 158.982 170.013 1.00 96.73  ? 79  VAL R CA  1 
ATOM   6019 C C   . VAL D 4 215 ? 154.598 157.569 169.672 1.00 98.75  ? 79  VAL R C   1 
ATOM   6020 O O   . VAL D 4 215 ? 153.886 157.351 168.684 1.00 97.67  ? 79  VAL R O   1 
ATOM   6021 C CB  . VAL D 4 215 ? 156.524 159.209 169.610 1.00 95.93  ? 79  VAL R CB  1 
ATOM   6022 N N   . GLY D 4 216 ? 154.999 156.590 170.487 1.00 96.62  ? 80  GLY R N   1 
ATOM   6023 C CA  . GLY D 4 216 ? 154.618 155.213 170.213 1.00 94.15  ? 80  GLY R CA  1 
ATOM   6024 C C   . GLY D 4 216 ? 153.120 155.000 170.264 1.00 93.87  ? 80  GLY R C   1 
ATOM   6025 O O   . GLY D 4 216 ? 152.538 154.375 169.375 1.00 95.01  ? 80  GLY R O   1 
ATOM   6026 N N   . ASN D 4 217 ? 152.470 155.523 171.306 1.00 87.58  ? 81  ASN R N   1 
ATOM   6027 C CA  . ASN D 4 217 ? 151.028 155.360 171.432 1.00 87.52  ? 81  ASN R CA  1 
ATOM   6028 C C   . ASN D 4 217 ? 150.281 156.092 170.326 1.00 90.11  ? 81  ASN R C   1 
ATOM   6029 O O   . ASN D 4 217 ? 149.288 155.572 169.802 1.00 90.38  ? 81  ASN R O   1 
ATOM   6030 C CB  . ASN D 4 217 ? 150.568 155.845 172.806 1.00 89.93  ? 81  ASN R CB  1 
ATOM   6031 N N   . THR D 4 218 ? 150.736 157.290 169.953 1.00 94.63  ? 82  THR R N   1 
ATOM   6032 C CA  . THR D 4 218 ? 150.111 158.039 168.872 1.00 94.44  ? 82  THR R CA  1 
ATOM   6033 C C   . THR D 4 218 ? 150.232 157.289 167.553 1.00 94.19  ? 82  THR R C   1 
ATOM   6034 O O   . THR D 4 218 ? 149.261 157.201 166.794 1.00 93.63  ? 82  THR R O   1 
ATOM   6035 C CB  . THR D 4 218 ? 150.743 159.427 168.750 1.00 94.38  ? 82  THR R CB  1 
ATOM   6036 N N   . VAL D 4 219 ? 151.417 156.740 167.273 1.00 92.06  ? 83  VAL R N   1 
ATOM   6037 C CA  . VAL D 4 219 ? 151.610 155.974 166.044 1.00 92.45  ? 83  VAL R CA  1 
ATOM   6038 C C   . VAL D 4 219 ? 150.735 154.729 166.050 1.00 93.97  ? 83  VAL R C   1 
ATOM   6039 O O   . VAL D 4 219 ? 150.134 154.368 165.030 1.00 91.01  ? 83  VAL R O   1 
ATOM   6040 C CB  . VAL D 4 219 ? 153.098 155.620 165.863 1.00 91.42  ? 83  VAL R CB  1 
ATOM   6041 N N   . THR D 4 220 ? 150.653 154.050 167.197 1.00 93.75  ? 84  THR R N   1 
ATOM   6042 C CA  . THR D 4 220 ? 149.826 152.852 167.304 1.00 91.24  ? 84  THR R CA  1 
ATOM   6043 C C   . THR D 4 220 ? 148.359 153.170 167.047 1.00 91.07  ? 84  THR R C   1 
ATOM   6044 O O   . THR D 4 220 ? 147.667 152.436 166.333 1.00 91.45  ? 84  THR R O   1 
ATOM   6045 C CB  . THR D 4 220 ? 150.001 152.219 168.685 1.00 91.72  ? 84  THR R CB  1 
ATOM   6046 O OG1 . THR D 4 220 ? 151.393 152.186 169.025 1.00 91.20  ? 84  THR R OG1 1 
ATOM   6047 C CG2 . THR D 4 220 ? 149.446 150.806 168.696 1.00 91.49  ? 84  THR R CG2 1 
ATOM   6048 N N   . ALA D 4 221 ? 147.865 154.264 167.629 1.00 93.28  ? 85  ALA R N   1 
ATOM   6049 C CA  . ALA D 4 221 ? 146.482 154.663 167.396 1.00 93.20  ? 85  ALA R CA  1 
ATOM   6050 C C   . ALA D 4 221 ? 146.258 155.047 165.939 1.00 93.51  ? 85  ALA R C   1 
ATOM   6051 O O   . ALA D 4 221 ? 145.223 154.711 165.352 1.00 93.16  ? 85  ALA R O   1 
ATOM   6052 C CB  . ALA D 4 221 ? 146.103 155.818 168.321 1.00 92.39  ? 85  ALA R CB  1 
ATOM   6053 N N   . PHE D 4 222 ? 147.215 155.761 165.342 1.00 96.24  ? 86  PHE R N   1 
ATOM   6054 C CA  . PHE D 4 222 ? 147.084 156.148 163.942 1.00 97.23  ? 86  PHE R CA  1 
ATOM   6055 C C   . PHE D 4 222 ? 147.132 154.934 163.023 1.00 96.30  ? 86  PHE R C   1 
ATOM   6056 O O   . PHE D 4 222 ? 146.365 154.851 162.057 1.00 96.45  ? 86  PHE R O   1 
ATOM   6057 C CB  . PHE D 4 222 ? 148.182 157.146 163.571 1.00 96.41  ? 86  PHE R CB  1 
ATOM   6058 N N   . THR D 4 223 ? 148.030 153.987 163.304 1.00 94.28  ? 87  THR R N   1 
ATOM   6059 C CA  . THR D 4 223 ? 148.152 152.804 162.457 1.00 93.93  ? 87  THR R CA  1 
ATOM   6060 C C   . THR D 4 223 ? 146.882 151.963 162.493 1.00 93.35  ? 87  THR R C   1 
ATOM   6061 O O   . THR D 4 223 ? 146.411 151.493 161.451 1.00 93.29  ? 87  THR R O   1 
ATOM   6062 C CB  . THR D 4 223 ? 149.359 151.974 162.895 1.00 94.10  ? 87  THR R CB  1 
ATOM   6063 O OG1 . THR D 4 223 ? 150.555 152.541 162.347 1.00 96.12  ? 87  THR R OG1 1 
ATOM   6064 C CG2 . THR D 4 223 ? 149.228 150.543 162.410 1.00 94.50  ? 87  THR R CG2 1 
ATOM   6065 N N   . LEU D 4 224 ? 146.305 151.775 163.681 1.00 93.48  ? 88  LEU R N   1 
ATOM   6066 C CA  . LEU D 4 224 ? 145.105 150.960 163.809 1.00 94.10  ? 88  LEU R CA  1 
ATOM   6067 C C   . LEU D 4 224 ? 143.883 151.614 163.182 1.00 94.14  ? 88  LEU R C   1 
ATOM   6068 O O   . LEU D 4 224 ? 142.907 150.916 162.889 1.00 93.90  ? 88  LEU R O   1 
ATOM   6069 C CB  . LEU D 4 224 ? 144.832 150.661 165.283 1.00 94.17  ? 88  LEU R CB  1 
ATOM   6070 C CG  . LEU D 4 224 ? 145.760 149.648 165.953 1.00 93.78  ? 88  LEU R CG  1 
ATOM   6071 C CD1 . LEU D 4 224 ? 145.533 149.630 167.453 1.00 92.51  ? 88  LEU R CD1 1 
ATOM   6072 C CD2 . LEU D 4 224 ? 145.551 148.266 165.361 1.00 94.46  ? 88  LEU R CD2 1 
ATOM   6073 N N   . ALA D 4 225 ? 143.907 152.933 162.975 1.00 92.89  ? 89  ALA R N   1 
ATOM   6074 C CA  . ALA D 4 225 ? 142.751 153.612 162.400 1.00 93.45  ? 89  ALA R CA  1 
ATOM   6075 C C   . ALA D 4 225 ? 142.524 153.186 160.955 1.00 95.89  ? 89  ALA R C   1 
ATOM   6076 O O   . ALA D 4 225 ? 141.406 152.823 160.571 1.00 97.82  ? 89  ALA R O   1 
ATOM   6077 C CB  . ALA D 4 225 ? 142.931 155.126 162.495 1.00 95.23  ? 89  ALA R CB  1 
ATOM   6078 N N   . ARG D 4 226 ? 143.574 153.223 160.139 1.00 92.97  ? 90  ARG R N   1 
ATOM   6079 C CA  . ARG D 4 226 ? 143.457 152.815 158.747 1.00 91.13  ? 90  ARG R CA  1 
ATOM   6080 C C   . ARG D 4 226 ? 143.222 151.313 158.654 1.00 91.17  ? 90  ARG R C   1 
ATOM   6081 O O   . ARG D 4 226 ? 143.822 150.526 159.392 1.00 90.34  ? 90  ARG R O   1 
ATOM   6082 C CB  . ARG D 4 226 ? 144.718 153.203 157.979 1.00 89.59  ? 90  ARG R CB  1 
ATOM   6083 C CG  . ARG D 4 226 ? 145.920 153.396 158.879 1.00 92.00  ? 90  ARG R CG  1 
ATOM   6084 C CD  . ARG D 4 226 ? 147.225 153.323 158.115 1.00 91.72  ? 90  ARG R CD  1 
ATOM   6085 N NE  . ARG D 4 226 ? 148.270 154.067 158.807 1.00 91.55  ? 90  ARG R NE  1 
ATOM   6086 C CZ  . ARG D 4 226 ? 149.378 154.518 158.238 1.00 92.06  ? 90  ARG R CZ  1 
ATOM   6087 N NH1 . ARG D 4 226 ? 149.625 154.324 156.953 1.00 92.74  ? 90  ARG R NH1 1 
ATOM   6088 N NH2 . ARG D 4 226 ? 150.261 155.181 158.977 1.00 90.59  ? 90  ARG R NH2 1 
ATOM   6089 N N   . LYS D 4 227 ? 142.349 150.916 157.733 1.00 80.67  ? 91  LYS R N   1 
ATOM   6090 C CA  . LYS D 4 227 ? 141.940 149.525 157.569 1.00 79.40  ? 91  LYS R CA  1 
ATOM   6091 C C   . LYS D 4 227 ? 142.203 149.062 156.146 1.00 78.15  ? 91  LYS R C   1 
ATOM   6092 O O   . LYS D 4 227 ? 141.349 148.470 155.481 1.00 75.40  ? 91  LYS R O   1 
ATOM   6093 C CB  . LYS D 4 227 ? 140.473 149.338 157.942 1.00 77.80  ? 91  LYS R CB  1 
ATOM   6094 C CG  . LYS D 4 227 ? 140.192 149.529 159.420 1.00 78.56  ? 91  LYS R CG  1 
ATOM   6095 C CD  . LYS D 4 227 ? 141.082 148.630 160.262 1.00 79.45  ? 91  LYS R CD  1 
ATOM   6096 C CE  . LYS D 4 227 ? 140.788 148.794 161.745 1.00 80.17  ? 91  LYS R CE  1 
ATOM   6097 N NZ  . LYS D 4 227 ? 141.795 148.102 162.597 1.00 78.75  ? 91  LYS R NZ  1 
ATOM   6098 N N   . LYS D 4 228 ? 143.413 149.335 155.658 1.00 63.55  ? 92  LYS R N   1 
ATOM   6099 C CA  . LYS D 4 228 ? 143.845 148.874 154.341 1.00 58.94  ? 92  LYS R CA  1 
ATOM   6100 C C   . LYS D 4 228 ? 144.186 147.383 154.393 1.00 59.60  ? 92  LYS R C   1 
ATOM   6101 O O   . LYS D 4 228 ? 145.323 146.957 154.197 1.00 57.90  ? 92  LYS R O   1 
ATOM   6102 C CB  . LYS D 4 228 ? 145.030 149.703 153.864 1.00 55.35  ? 92  LYS R CB  1 
ATOM   6103 N N   . SER D 4 229 ? 143.153 146.588 154.663 1.00 58.78  ? 93  SER R N   1 
ATOM   6104 C CA  . SER D 4 229 ? 143.273 145.146 154.825 1.00 55.54  ? 93  SER R CA  1 
ATOM   6105 C C   . SER D 4 229 ? 141.872 144.560 154.907 1.00 54.49  ? 93  SER R C   1 
ATOM   6106 O O   . SER D 4 229 ? 140.888 145.285 155.081 1.00 53.11  ? 93  SER R O   1 
ATOM   6107 C CB  . SER D 4 229 ? 144.086 144.782 156.074 1.00 53.72  ? 93  SER R CB  1 
ATOM   6108 O OG  . SER D 4 229 ? 144.128 143.381 156.275 1.00 54.36  ? 93  SER R OG  1 
ATOM   6109 N N   . LEU D 4 230 ? 141.794 143.239 154.777 1.00 53.64  ? 94  LEU R N   1 
ATOM   6110 C CA  . LEU D 4 230 ? 140.541 142.516 154.943 1.00 51.83  ? 94  LEU R CA  1 
ATOM   6111 C C   . LEU D 4 230 ? 140.396 142.113 156.405 1.00 56.19  ? 94  LEU R C   1 
ATOM   6112 O O   . LEU D 4 230 ? 141.183 141.305 156.912 1.00 58.56  ? 94  LEU R O   1 
ATOM   6113 C CB  . LEU D 4 230 ? 140.500 141.291 154.033 1.00 50.77  ? 94  LEU R CB  1 
ATOM   6114 N N   . GLN D 4 231 ? 139.395 142.672 157.079 1.00 61.49  ? 95  GLN R N   1 
ATOM   6115 C CA  . GLN D 4 231 ? 139.206 142.495 158.512 1.00 60.84  ? 95  GLN R CA  1 
ATOM   6116 C C   . GLN D 4 231 ? 138.040 141.551 158.770 1.00 58.28  ? 95  GLN R C   1 
ATOM   6117 O O   . GLN D 4 231 ? 136.956 141.728 158.205 1.00 58.05  ? 95  GLN R O   1 
ATOM   6118 C CB  . GLN D 4 231 ? 138.958 143.839 159.199 1.00 58.07  ? 95  GLN R CB  1 
ATOM   6119 N N   . SER D 4 232 ? 138.265 140.562 159.631 1.00 67.00  ? 96  SER R N   1 
ATOM   6120 C CA  . SER D 4 232 ? 137.239 139.575 159.931 1.00 68.39  ? 96  SER R CA  1 
ATOM   6121 C C   . SER D 4 232 ? 136.095 140.197 160.722 1.00 71.12  ? 96  SER R C   1 
ATOM   6122 O O   . SER D 4 232 ? 136.274 141.162 161.468 1.00 75.20  ? 96  SER R O   1 
ATOM   6123 C CB  . SER D 4 232 ? 137.835 138.408 160.716 1.00 67.44  ? 96  SER R CB  1 
ATOM   6124 O OG  . SER D 4 232 ? 136.827 137.505 161.130 1.00 68.63  ? 96  SER R OG  1 
ATOM   6125 N N   . LEU D 4 233 ? 134.903 139.621 160.552 1.00 81.77  ? 97  LEU R N   1 
ATOM   6126 C CA  . LEU D 4 233 ? 133.710 140.089 161.246 1.00 80.63  ? 97  LEU R CA  1 
ATOM   6127 C C   . LEU D 4 233 ? 133.763 139.831 162.747 1.00 82.17  ? 97  LEU R C   1 
ATOM   6128 O O   . LEU D 4 233 ? 132.982 140.433 163.490 1.00 83.86  ? 97  LEU R O   1 
ATOM   6129 C CB  . LEU D 4 233 ? 132.472 139.423 160.635 1.00 82.01  ? 97  LEU R CB  1 
ATOM   6130 C CG  . LEU D 4 233 ? 131.072 139.780 161.141 1.00 83.00  ? 97  LEU R CG  1 
ATOM   6131 C CD1 . LEU D 4 233 ? 130.122 139.980 159.972 1.00 81.31  ? 97  LEU R CD1 1 
ATOM   6132 C CD2 . LEU D 4 233 ? 130.548 138.704 162.079 1.00 79.83  ? 97  LEU R CD2 1 
ATOM   6133 N N   . GLN D 4 234 ? 134.657 138.962 163.211 1.00 89.16  ? 98  GLN R N   1 
ATOM   6134 C CA  . GLN D 4 234 ? 134.801 138.650 164.627 1.00 89.81  ? 98  GLN R CA  1 
ATOM   6135 C C   . GLN D 4 234 ? 136.246 138.822 165.070 1.00 89.90  ? 98  GLN R C   1 
ATOM   6136 O O   . GLN D 4 234 ? 136.768 138.044 165.873 1.00 92.12  ? 98  GLN R O   1 
ATOM   6137 C CB  . GLN D 4 234 ? 134.309 137.236 164.928 1.00 90.93  ? 98  GLN R CB  1 
ATOM   6138 N N   . SER D 4 235 ? 136.916 139.846 164.549 1.00 91.65  ? 99  SER R N   1 
ATOM   6139 C CA  . SER D 4 235 ? 138.295 140.166 164.911 1.00 93.53  ? 99  SER R CA  1 
ATOM   6140 C C   . SER D 4 235 ? 138.275 141.466 165.707 1.00 94.17  ? 99  SER R C   1 
ATOM   6141 O O   . SER D 4 235 ? 138.077 142.545 165.142 1.00 94.45  ? 99  SER R O   1 
ATOM   6142 C CB  . SER D 4 235 ? 139.175 140.282 163.671 1.00 92.31  ? 99  SER R CB  1 
ATOM   6143 O OG  . SER D 4 235 ? 140.488 140.686 164.013 1.00 90.16  ? 99  SER R OG  1 
ATOM   6144 N N   . THR D 4 236 ? 138.478 141.360 167.021 1.00 96.67  ? 100 THR R N   1 
ATOM   6145 C CA  . THR D 4 236 ? 138.425 142.511 167.915 1.00 95.48  ? 100 THR R CA  1 
ATOM   6146 C C   . THR D 4 236 ? 139.733 142.717 168.670 1.00 96.05  ? 100 THR R C   1 
ATOM   6147 O O   . THR D 4 236 ? 139.751 143.408 169.692 1.00 98.96  ? 100 THR R O   1 
ATOM   6148 C CB  . THR D 4 236 ? 137.267 142.366 168.903 1.00 95.33  ? 100 THR R CB  1 
ATOM   6149 N N   . VAL D 4 237 ? 140.831 142.129 168.189 1.00 92.94  ? 101 VAL R N   1 
ATOM   6150 C CA  . VAL D 4 237 ? 142.115 142.302 168.859 1.00 91.51  ? 101 VAL R CA  1 
ATOM   6151 C C   . VAL D 4 237 ? 142.580 143.749 168.775 1.00 92.08  ? 101 VAL R C   1 
ATOM   6152 O O   . VAL D 4 237 ? 143.217 144.258 169.705 1.00 92.92  ? 101 VAL R O   1 
ATOM   6153 C CB  . VAL D 4 237 ? 143.162 141.341 168.269 1.00 92.27  ? 101 VAL R CB  1 
ATOM   6154 N N   . HIS D 4 238 ? 142.285 144.432 167.667 1.00 92.98  ? 102 HIS R N   1 
ATOM   6155 C CA  . HIS D 4 238 ? 142.721 145.816 167.519 1.00 93.01  ? 102 HIS R CA  1 
ATOM   6156 C C   . HIS D 4 238 ? 141.982 146.748 168.470 1.00 94.69  ? 102 HIS R C   1 
ATOM   6157 O O   . HIS D 4 238 ? 142.517 147.798 168.841 1.00 93.78  ? 102 HIS R O   1 
ATOM   6158 C CB  . HIS D 4 238 ? 142.539 146.276 166.073 1.00 93.37  ? 102 HIS R CB  1 
ATOM   6159 C CG  . HIS D 4 238 ? 141.120 146.239 165.599 1.00 94.56  ? 102 HIS R CG  1 
ATOM   6160 N ND1 . HIS D 4 238 ? 140.475 145.067 165.267 1.00 93.97  ? 102 HIS R ND1 1 
ATOM   6161 C CD2 . HIS D 4 238 ? 140.222 147.232 165.397 1.00 96.69  ? 102 HIS R CD2 1 
ATOM   6162 C CE1 . HIS D 4 238 ? 139.241 145.339 164.883 1.00 95.40  ? 102 HIS R CE1 1 
ATOM   6163 N NE2 . HIS D 4 238 ? 139.062 146.645 164.954 1.00 97.94  ? 102 HIS R NE2 1 
ATOM   6164 N N   . TYR D 4 239 ? 140.758 146.390 168.870 1.00 99.91  ? 103 TYR R N   1 
ATOM   6165 C CA  . TYR D 4 239 ? 140.009 147.221 169.809 1.00 99.10  ? 103 TYR R CA  1 
ATOM   6166 C C   . TYR D 4 239 ? 140.748 147.354 171.135 1.00 96.87  ? 103 TYR R C   1 
ATOM   6167 O O   . TYR D 4 239 ? 140.918 148.460 171.661 1.00 96.11  ? 103 TYR R O   1 
ATOM   6168 C CB  . TYR D 4 239 ? 138.616 146.631 170.035 1.00 99.18  ? 103 TYR R CB  1 
ATOM   6169 C CG  . TYR D 4 239 ? 137.614 146.951 168.952 1.00 99.64  ? 103 TYR R CG  1 
ATOM   6170 C CD1 . TYR D 4 239 ? 137.778 148.057 168.129 1.00 98.70  ? 103 TYR R CD1 1 
ATOM   6171 C CD2 . TYR D 4 239 ? 136.499 146.147 168.754 1.00 100.12 ? 103 TYR R CD2 1 
ATOM   6172 C CE1 . TYR D 4 239 ? 136.861 148.352 167.137 1.00 99.56  ? 103 TYR R CE1 1 
ATOM   6173 C CE2 . TYR D 4 239 ? 135.577 146.433 167.766 1.00 99.33  ? 103 TYR R CE2 1 
ATOM   6174 C CZ  . TYR D 4 239 ? 135.763 147.536 166.960 1.00 99.67  ? 103 TYR R CZ  1 
ATOM   6175 O OH  . TYR D 4 239 ? 134.847 147.825 165.975 1.00 99.75  ? 103 TYR R OH  1 
ATOM   6176 N N   . HIS D 4 240 ? 141.199 146.228 171.689 1.00 89.91  ? 104 HIS R N   1 
ATOM   6177 C CA  . HIS D 4 240 ? 141.896 146.264 172.969 1.00 90.53  ? 104 HIS R CA  1 
ATOM   6178 C C   . HIS D 4 240 ? 143.257 146.934 172.838 1.00 92.28  ? 104 HIS R C   1 
ATOM   6179 O O   . HIS D 4 240 ? 143.702 147.627 173.759 1.00 92.06  ? 104 HIS R O   1 
ATOM   6180 C CB  . HIS D 4 240 ? 142.032 144.850 173.527 1.00 91.07  ? 104 HIS R CB  1 
ATOM   6181 C CG  . HIS D 4 240 ? 140.720 144.169 173.758 1.00 92.08  ? 104 HIS R CG  1 
ATOM   6182 N ND1 . HIS D 4 240 ? 139.928 144.431 174.855 1.00 93.18  ? 104 HIS R ND1 1 
ATOM   6183 C CD2 . HIS D 4 240 ? 140.057 143.240 173.029 1.00 93.39  ? 104 HIS R CD2 1 
ATOM   6184 C CE1 . HIS D 4 240 ? 138.836 143.690 174.794 1.00 93.10  ? 104 HIS R CE1 1 
ATOM   6185 N NE2 . HIS D 4 240 ? 138.890 142.959 173.696 1.00 92.83  ? 104 HIS R NE2 1 
ATOM   6186 N N   . LEU D 4 241 ? 143.931 146.746 171.700 1.00 91.50  ? 105 LEU R N   1 
ATOM   6187 C CA  . LEU D 4 241 ? 145.191 147.444 171.470 1.00 90.11  ? 105 LEU R CA  1 
ATOM   6188 C C   . LEU D 4 241 ? 144.982 148.952 171.465 1.00 91.80  ? 105 LEU R C   1 
ATOM   6189 O O   . LEU D 4 241 ? 145.748 149.700 172.082 1.00 93.26  ? 105 LEU R O   1 
ATOM   6190 C CB  . LEU D 4 241 ? 145.816 146.993 170.151 1.00 89.18  ? 105 LEU R CB  1 
ATOM   6191 C CG  . LEU D 4 241 ? 146.310 145.554 170.019 1.00 89.32  ? 105 LEU R CG  1 
ATOM   6192 C CD1 . LEU D 4 241 ? 147.436 145.502 169.009 1.00 91.23  ? 105 LEU R CD1 1 
ATOM   6193 C CD2 . LEU D 4 241 ? 146.763 145.006 171.355 1.00 89.35  ? 105 LEU R CD2 1 
ATOM   6194 N N   . GLY D 4 242 ? 143.940 149.414 170.772 1.00 88.24  ? 106 GLY R N   1 
ATOM   6195 C CA  . GLY D 4 242 ? 143.657 150.838 170.746 1.00 87.03  ? 106 GLY R CA  1 
ATOM   6196 C C   . GLY D 4 242 ? 143.280 151.379 172.110 1.00 87.06  ? 106 GLY R C   1 
ATOM   6197 O O   . GLY D 4 242 ? 143.712 152.467 172.498 1.00 88.40  ? 106 GLY R O   1 
ATOM   6198 N N   . SER D 4 243 ? 142.473 150.625 172.858 1.00 85.63  ? 107 SER R N   1 
ATOM   6199 C CA  . SER D 4 243 ? 142.101 151.060 174.200 1.00 86.05  ? 107 SER R CA  1 
ATOM   6200 C C   . SER D 4 243 ? 143.321 151.162 175.105 1.00 85.75  ? 107 SER R C   1 
ATOM   6201 O O   . SER D 4 243 ? 143.468 152.137 175.852 1.00 86.24  ? 107 SER R O   1 
ATOM   6202 C CB  . SER D 4 243 ? 141.069 150.103 174.796 1.00 88.01  ? 107 SER R CB  1 
ATOM   6203 O OG  . SER D 4 243 ? 140.937 150.305 176.192 1.00 86.17  ? 107 SER R OG  1 
ATOM   6204 N N   . LEU D 4 244 ? 144.212 150.169 175.050 1.00 83.78  ? 108 LEU R N   1 
ATOM   6205 C CA  . LEU D 4 244 ? 145.413 150.206 175.877 1.00 83.86  ? 108 LEU R CA  1 
ATOM   6206 C C   . LEU D 4 244 ? 146.329 151.354 175.473 1.00 85.67  ? 108 LEU R C   1 
ATOM   6207 O O   . LEU D 4 244 ? 146.901 152.030 176.336 1.00 86.94  ? 108 LEU R O   1 
ATOM   6208 C CB  . LEU D 4 244 ? 146.149 148.870 175.793 1.00 82.55  ? 108 LEU R CB  1 
ATOM   6209 C CG  . LEU D 4 244 ? 147.474 148.769 176.551 1.00 83.67  ? 108 LEU R CG  1 
ATOM   6210 C CD1 . LEU D 4 244 ? 147.314 149.211 177.995 1.00 84.91  ? 108 LEU R CD1 1 
ATOM   6211 C CD2 . LEU D 4 244 ? 148.018 147.354 176.485 1.00 84.61  ? 108 LEU R CD2 1 
ATOM   6212 N N   . ALA D 4 245 ? 146.483 151.590 174.167 1.00 84.57  ? 109 ALA R N   1 
ATOM   6213 C CA  . ALA D 4 245 ? 147.310 152.704 173.714 1.00 83.46  ? 109 ALA R CA  1 
ATOM   6214 C C   . ALA D 4 245 ? 146.741 154.036 174.180 1.00 85.42  ? 109 ALA R C   1 
ATOM   6215 O O   . ALA D 4 245 ? 147.485 154.911 174.641 1.00 85.03  ? 109 ALA R O   1 
ATOM   6216 C CB  . ALA D 4 245 ? 147.436 152.678 172.192 1.00 82.48  ? 109 ALA R CB  1 
ATOM   6217 N N   . LEU D 4 246 ? 145.421 154.207 174.076 1.00 87.72  ? 110 LEU R N   1 
ATOM   6218 C CA  . LEU D 4 246 ? 144.799 155.446 174.525 1.00 85.94  ? 110 LEU R CA  1 
ATOM   6219 C C   . LEU D 4 246 ? 144.948 155.627 176.030 1.00 86.57  ? 110 LEU R C   1 
ATOM   6220 O O   . LEU D 4 246 ? 145.207 156.738 176.504 1.00 86.11  ? 110 LEU R O   1 
ATOM   6221 C CB  . LEU D 4 246 ? 143.325 155.469 174.125 1.00 86.57  ? 110 LEU R CB  1 
ATOM   6222 C CG  . LEU D 4 246 ? 142.592 156.784 174.392 1.00 87.99  ? 110 LEU R CG  1 
ATOM   6223 C CD1 . LEU D 4 246 ? 141.932 157.294 173.121 1.00 86.11  ? 110 LEU R CD1 1 
ATOM   6224 C CD2 . LEU D 4 246 ? 141.571 156.616 175.502 1.00 88.45  ? 110 LEU R CD2 1 
ATOM   6225 N N   . SER D 4 247 ? 144.780 154.548 176.799 1.00 85.84  ? 111 SER R N   1 
ATOM   6226 C CA  . SER D 4 247 ? 144.929 154.645 178.247 1.00 84.86  ? 111 SER R CA  1 
ATOM   6227 C C   . SER D 4 247 ? 146.360 154.998 178.632 1.00 86.19  ? 111 SER R C   1 
ATOM   6228 O O   . SER D 4 247 ? 146.585 155.815 179.535 1.00 87.74  ? 111 SER R O   1 
ATOM   6229 C CB  . SER D 4 247 ? 144.501 153.336 178.906 1.00 84.75  ? 111 SER R CB  1 
ATOM   6230 N N   . ASP D 4 248 ? 147.343 154.395 177.958 1.00 83.55  ? 112 ASP R N   1 
ATOM   6231 C CA  . ASP D 4 248 ? 148.738 154.720 178.237 1.00 83.59  ? 112 ASP R CA  1 
ATOM   6232 C C   . ASP D 4 248 ? 149.051 156.165 177.871 1.00 85.77  ? 112 ASP R C   1 
ATOM   6233 O O   . ASP D 4 248 ? 149.758 156.860 178.609 1.00 86.07  ? 112 ASP R O   1 
ATOM   6234 C CB  . ASP D 4 248 ? 149.662 153.762 177.487 1.00 84.41  ? 112 ASP R CB  1 
ATOM   6235 N N   . LEU D 4 249 ? 148.528 156.640 176.738 1.00 85.78  ? 113 LEU R N   1 
ATOM   6236 C CA  . LEU D 4 249 ? 148.733 158.034 176.362 1.00 85.02  ? 113 LEU R CA  1 
ATOM   6237 C C   . LEU D 4 249 ? 148.100 158.980 177.374 1.00 87.30  ? 113 LEU R C   1 
ATOM   6238 O O   . LEU D 4 249 ? 148.700 159.994 177.748 1.00 88.56  ? 113 LEU R O   1 
ATOM   6239 C CB  . LEU D 4 249 ? 148.168 158.291 174.966 1.00 84.68  ? 113 LEU R CB  1 
ATOM   6240 N N   . LEU D 4 250 ? 146.881 158.670 177.824 1.00 88.76  ? 114 LEU R N   1 
ATOM   6241 C CA  . LEU D 4 250 ? 146.215 159.517 178.806 1.00 86.73  ? 114 LEU R CA  1 
ATOM   6242 C C   . LEU D 4 250 ? 146.991 159.551 180.115 1.00 88.07  ? 114 LEU R C   1 
ATOM   6243 O O   . LEU D 4 250 ? 147.149 160.615 180.724 1.00 90.93  ? 114 LEU R O   1 
ATOM   6244 C CB  . LEU D 4 250 ? 144.786 159.028 179.038 1.00 83.71  ? 114 LEU R CB  1 
ATOM   6245 N N   . THR D 4 251 ? 147.492 158.396 180.558 1.00 88.07  ? 115 THR R N   1 
ATOM   6246 C CA  . THR D 4 251 ? 148.313 158.369 181.764 1.00 87.71  ? 115 THR R CA  1 
ATOM   6247 C C   . THR D 4 251 ? 149.586 159.183 181.578 1.00 90.01  ? 115 THR R C   1 
ATOM   6248 O O   . THR D 4 251 ? 150.016 159.895 182.492 1.00 91.41  ? 115 THR R O   1 
ATOM   6249 C CB  . THR D 4 251 ? 148.650 156.927 182.140 1.00 88.05  ? 115 THR R CB  1 
ATOM   6250 N N   . LEU D 4 252 ? 150.200 159.097 180.395 1.00 94.15  ? 116 LEU R N   1 
ATOM   6251 C CA  . LEU D 4 252 ? 151.453 159.805 180.159 1.00 93.81  ? 116 LEU R CA  1 
ATOM   6252 C C   . LEU D 4 252 ? 151.257 161.315 180.114 1.00 95.08  ? 116 LEU R C   1 
ATOM   6253 O O   . LEU D 4 252 ? 152.114 162.061 180.600 1.00 97.60  ? 116 LEU R O   1 
ATOM   6254 C CB  . LEU D 4 252 ? 152.095 159.313 178.864 1.00 93.59  ? 116 LEU R CB  1 
ATOM   6255 C CG  . LEU D 4 252 ? 152.550 157.853 178.852 1.00 95.71  ? 116 LEU R CG  1 
ATOM   6256 C CD1 . LEU D 4 252 ? 153.028 157.464 177.470 1.00 95.83  ? 116 LEU R CD1 1 
ATOM   6257 C CD2 . LEU D 4 252 ? 153.645 157.614 179.879 1.00 94.77  ? 116 LEU R CD2 1 
ATOM   6258 N N   . LEU D 4 253 ? 150.155 161.788 179.535 1.00 94.35  ? 117 LEU R N   1 
ATOM   6259 C CA  . LEU D 4 253 ? 149.898 163.222 179.474 1.00 92.33  ? 117 LEU R CA  1 
ATOM   6260 C C   . LEU D 4 253 ? 149.181 163.762 180.703 1.00 91.74  ? 117 LEU R C   1 
ATOM   6261 O O   . LEU D 4 253 ? 149.044 164.983 180.827 1.00 94.12  ? 117 LEU R O   1 
ATOM   6262 C CB  . LEU D 4 253 ? 149.077 163.584 178.229 1.00 92.02  ? 117 LEU R CB  1 
ATOM   6263 C CG  . LEU D 4 253 ? 149.340 162.863 176.909 1.00 93.25  ? 117 LEU R CG  1 
ATOM   6264 C CD1 . LEU D 4 253 ? 148.119 162.956 176.013 1.00 92.28  ? 117 LEU R CD1 1 
ATOM   6265 C CD2 . LEU D 4 253 ? 150.560 163.439 176.215 1.00 92.90  ? 117 LEU R CD2 1 
ATOM   6266 N N   . LEU D 4 254 ? 148.723 162.900 181.608 1.00 92.37  ? 118 LEU R N   1 
ATOM   6267 C CA  . LEU D 4 254 ? 147.937 163.348 182.750 1.00 92.68  ? 118 LEU R CA  1 
ATOM   6268 C C   . LEU D 4 254 ? 148.634 163.184 184.090 1.00 92.23  ? 118 LEU R C   1 
ATOM   6269 O O   . LEU D 4 254 ? 148.342 163.945 185.014 1.00 92.61  ? 118 LEU R O   1 
ATOM   6270 C CB  . LEU D 4 254 ? 146.600 162.595 182.801 1.00 92.43  ? 118 LEU R CB  1 
ATOM   6271 C CG  . LEU D 4 254 ? 145.392 163.226 182.105 1.00 92.39  ? 118 LEU R CG  1 
ATOM   6272 C CD1 . LEU D 4 254 ? 145.692 163.563 180.652 1.00 90.35  ? 118 LEU R CD1 1 
ATOM   6273 C CD2 . LEU D 4 254 ? 144.193 162.299 182.200 1.00 93.13  ? 118 LEU R CD2 1 
ATOM   6274 N N   . ALA D 4 255 ? 149.545 162.223 184.222 1.00 96.78  ? 119 ALA R N   1 
ATOM   6275 C CA  . ALA D 4 255 ? 150.127 161.898 185.518 1.00 97.65  ? 119 ALA R CA  1 
ATOM   6276 C C   . ALA D 4 255 ? 151.462 162.582 185.777 1.00 100.02 ? 119 ALA R C   1 
ATOM   6277 O O   . ALA D 4 255 ? 151.629 163.217 186.822 1.00 100.22 ? 119 ALA R O   1 
ATOM   6278 C CB  . ALA D 4 255 ? 150.303 160.383 185.652 1.00 97.33  ? 119 ALA R CB  1 
ATOM   6279 N N   . MET D 4 256 ? 152.421 162.471 184.861 1.00 108.98 ? 120 MET R N   1 
ATOM   6280 C CA  . MET D 4 256 ? 153.765 162.965 185.144 1.00 109.82 ? 120 MET R CA  1 
ATOM   6281 C C   . MET D 4 256 ? 153.912 164.488 185.115 1.00 109.76 ? 120 MET R C   1 
ATOM   6282 O O   . MET D 4 256 ? 154.712 165.014 185.899 1.00 108.38 ? 120 MET R O   1 
ATOM   6283 C CB  . MET D 4 256 ? 154.785 162.320 184.199 1.00 109.35 ? 120 MET R CB  1 
ATOM   6284 C CG  . MET D 4 256 ? 154.358 162.172 182.759 1.00 109.13 ? 120 MET R CG  1 
ATOM   6285 S SD  . MET D 4 256 ? 155.767 162.244 181.643 1.00 112.84 ? 120 MET R SD  1 
ATOM   6286 C CE  . MET D 4 256 ? 156.550 160.670 181.980 1.00 109.44 ? 120 MET R CE  1 
ATOM   6287 N N   . PRO D 4 257 ? 153.209 165.243 184.252 1.00 108.91 ? 121 PRO R N   1 
ATOM   6288 C CA  . PRO D 4 257 ? 153.348 166.709 184.342 1.00 107.88 ? 121 PRO R CA  1 
ATOM   6289 C C   . PRO D 4 257 ? 152.991 167.254 185.713 1.00 107.26 ? 121 PRO R C   1 
ATOM   6290 O O   . PRO D 4 257 ? 153.650 168.180 186.201 1.00 107.09 ? 121 PRO R O   1 
ATOM   6291 C CB  . PRO D 4 257 ? 152.396 167.220 183.253 1.00 107.03 ? 121 PRO R CB  1 
ATOM   6292 C CG  . PRO D 4 257 ? 152.311 166.109 182.287 1.00 106.52 ? 121 PRO R CG  1 
ATOM   6293 C CD  . PRO D 4 257 ? 152.333 164.870 183.125 1.00 106.45 ? 121 PRO R CD  1 
ATOM   6294 N N   . VAL D 4 258 ? 151.960 166.699 186.352 1.00 110.21 ? 122 VAL R N   1 
ATOM   6295 C CA  . VAL D 4 258 ? 151.674 167.052 187.737 1.00 110.45 ? 122 VAL R CA  1 
ATOM   6296 C C   . VAL D 4 258 ? 152.729 166.463 188.665 1.00 110.91 ? 122 VAL R C   1 
ATOM   6297 O O   . VAL D 4 258 ? 153.178 167.117 189.613 1.00 109.79 ? 122 VAL R O   1 
ATOM   6298 C CB  . VAL D 4 258 ? 150.257 166.590 188.124 1.00 109.46 ? 122 VAL R CB  1 
ATOM   6299 N N   . GLU D 4 259 ? 153.143 165.220 188.406 1.00 114.95 ? 123 GLU R N   1 
ATOM   6300 C CA  . GLU D 4 259 ? 154.077 164.535 189.292 1.00 114.91 ? 123 GLU R CA  1 
ATOM   6301 C C   . GLU D 4 259 ? 155.500 165.061 189.165 1.00 115.42 ? 123 GLU R C   1 
ATOM   6302 O O   . GLU D 4 259 ? 156.281 164.929 190.114 1.00 115.05 ? 123 GLU R O   1 
ATOM   6303 C CB  . GLU D 4 259 ? 154.056 163.032 189.015 1.00 112.72 ? 123 GLU R CB  1 
ATOM   6304 N N   . LEU D 4 260 ? 155.860 165.642 188.019 1.00 116.61 ? 124 LEU R N   1 
ATOM   6305 C CA  . LEU D 4 260 ? 157.213 166.161 187.859 1.00 116.87 ? 124 LEU R CA  1 
ATOM   6306 C C   . LEU D 4 260 ? 157.417 167.451 188.643 1.00 118.24 ? 124 LEU R C   1 
ATOM   6307 O O   . LEU D 4 260 ? 158.546 167.761 189.041 1.00 117.32 ? 124 LEU R O   1 
ATOM   6308 C CB  . LEU D 4 260 ? 157.518 166.381 186.377 1.00 115.67 ? 124 LEU R CB  1 
ATOM   6309 C CG  . LEU D 4 260 ? 158.982 166.617 186.004 1.00 115.49 ? 124 LEU R CG  1 
ATOM   6310 C CD1 . LEU D 4 260 ? 159.819 165.395 186.342 1.00 115.28 ? 124 LEU R CD1 1 
ATOM   6311 C CD2 . LEU D 4 260 ? 159.106 166.960 184.530 1.00 115.79 ? 124 LEU R CD2 1 
ATOM   6312 N N   . TYR D 4 261 ? 156.346 168.207 188.884 1.00 122.46 ? 125 TYR R N   1 
ATOM   6313 C CA  . TYR D 4 261 ? 156.451 169.484 189.584 1.00 121.88 ? 125 TYR R CA  1 
ATOM   6314 C C   . TYR D 4 261 ? 156.184 169.339 191.080 1.00 121.29 ? 125 TYR R C   1 
ATOM   6315 O O   . TYR D 4 261 ? 157.040 169.674 191.905 1.00 121.00 ? 125 TYR R O   1 
ATOM   6316 C CB  . TYR D 4 261 ? 155.486 170.502 188.964 1.00 121.44 ? 125 TYR R CB  1 
ATOM   6317 C CG  . TYR D 4 261 ? 155.335 171.772 189.772 1.00 121.95 ? 125 TYR R CG  1 
ATOM   6318 C CD1 . TYR D 4 261 ? 156.297 172.772 189.715 1.00 121.54 ? 125 TYR R CD1 1 
ATOM   6319 C CD2 . TYR D 4 261 ? 154.231 171.971 190.590 1.00 121.33 ? 125 TYR R CD2 1 
ATOM   6320 C CE1 . TYR D 4 261 ? 156.164 173.933 190.452 1.00 120.79 ? 125 TYR R CE1 1 
ATOM   6321 C CE2 . TYR D 4 261 ? 154.090 173.128 191.330 1.00 121.89 ? 125 TYR R CE2 1 
ATOM   6322 C CZ  . TYR D 4 261 ? 155.059 174.106 191.257 1.00 122.07 ? 125 TYR R CZ  1 
ATOM   6323 O OH  . TYR D 4 261 ? 154.920 175.259 191.993 1.00 122.14 ? 125 TYR R OH  1 
ATOM   6324 N N   . ASN D 4 262 ? 155.003 168.838 191.443 1.00 118.20 ? 126 ASN R N   1 
ATOM   6325 C CA  . ASN D 4 262 ? 154.578 168.820 192.837 1.00 118.29 ? 126 ASN R CA  1 
ATOM   6326 C C   . ASN D 4 262 ? 155.175 167.672 193.641 1.00 118.82 ? 126 ASN R C   1 
ATOM   6327 O O   . ASN D 4 262 ? 155.026 167.661 194.868 1.00 117.51 ? 126 ASN R O   1 
ATOM   6328 C CB  . ASN D 4 262 ? 153.051 168.753 192.918 1.00 117.62 ? 126 ASN R CB  1 
ATOM   6329 N N   . PHE D 4 263 ? 155.838 166.713 192.995 1.00 120.42 ? 127 PHE R N   1 
ATOM   6330 C CA  . PHE D 4 263 ? 156.394 165.572 193.714 1.00 119.31 ? 127 PHE R CA  1 
ATOM   6331 C C   . PHE D 4 263 ? 157.875 165.375 193.414 1.00 119.04 ? 127 PHE R C   1 
ATOM   6332 O O   . PHE D 4 263 ? 158.636 164.942 194.286 1.00 118.06 ? 127 PHE R O   1 
ATOM   6333 C CB  . PHE D 4 263 ? 155.620 164.297 193.372 1.00 117.64 ? 127 PHE R CB  1 
ATOM   6334 C CG  . PHE D 4 263 ? 154.160 164.358 193.719 1.00 117.96 ? 127 PHE R CG  1 
ATOM   6335 C CD1 . PHE D 4 263 ? 153.753 164.524 195.031 1.00 118.25 ? 127 PHE R CD1 1 
ATOM   6336 C CD2 . PHE D 4 263 ? 153.194 164.236 192.734 1.00 117.57 ? 127 PHE R CD2 1 
ATOM   6337 C CE1 . PHE D 4 263 ? 152.412 164.575 195.353 1.00 118.89 ? 127 PHE R CE1 1 
ATOM   6338 C CE2 . PHE D 4 263 ? 151.852 164.285 193.048 1.00 117.17 ? 127 PHE R CE2 1 
ATOM   6339 C CZ  . PHE D 4 263 ? 151.460 164.455 194.359 1.00 118.28 ? 127 PHE R CZ  1 
ATOM   6340 N N   . ILE D 4 264 ? 158.294 165.681 192.190 1.00 121.14 ? 128 ILE R N   1 
ATOM   6341 C CA  . ILE D 4 264 ? 159.674 165.441 191.778 1.00 120.38 ? 128 ILE R CA  1 
ATOM   6342 C C   . ILE D 4 264 ? 160.546 166.669 191.999 1.00 121.34 ? 128 ILE R C   1 
ATOM   6343 O O   . ILE D 4 264 ? 161.614 166.582 192.610 1.00 121.71 ? 128 ILE R O   1 
ATOM   6344 C CB  . ILE D 4 264 ? 159.715 164.981 190.305 1.00 119.56 ? 128 ILE R CB  1 
ATOM   6345 N N   . TRP D 4 265 ? 160.112 167.832 191.510 1.00 124.64 ? 129 TRP R N   1 
ATOM   6346 C CA  . TRP D 4 265 ? 160.928 169.036 191.633 1.00 125.09 ? 129 TRP R CA  1 
ATOM   6347 C C   . TRP D 4 265 ? 160.777 169.676 193.010 1.00 126.02 ? 129 TRP R C   1 
ATOM   6348 O O   . TRP D 4 265 ? 161.744 169.771 193.773 1.00 125.36 ? 129 TRP R O   1 
ATOM   6349 C CB  . TRP D 4 265 ? 160.562 170.037 190.534 1.00 124.22 ? 129 TRP R CB  1 
ATOM   6350 C CG  . TRP D 4 265 ? 161.273 169.806 189.232 1.00 125.58 ? 129 TRP R CG  1 
ATOM   6351 C CD1 . TRP D 4 265 ? 160.698 169.599 188.012 1.00 125.79 ? 129 TRP R CD1 1 
ATOM   6352 C CD2 . TRP D 4 265 ? 162.690 169.763 189.018 1.00 125.89 ? 129 TRP R CD2 1 
ATOM   6353 N NE1 . TRP D 4 265 ? 161.666 169.429 187.053 1.00 125.49 ? 129 TRP R NE1 1 
ATOM   6354 C CE2 . TRP D 4 265 ? 162.898 169.525 187.645 1.00 125.75 ? 129 TRP R CE2 1 
ATOM   6355 C CE3 . TRP D 4 265 ? 163.803 169.903 189.854 1.00 124.77 ? 129 TRP R CE3 1 
ATOM   6356 C CZ2 . TRP D 4 265 ? 164.171 169.422 187.089 1.00 124.39 ? 129 TRP R CZ2 1 
ATOM   6357 C CZ3 . TRP D 4 265 ? 165.065 169.800 189.299 1.00 125.16 ? 129 TRP R CZ3 1 
ATOM   6358 C CH2 . TRP D 4 265 ? 165.239 169.563 187.930 1.00 124.59 ? 129 TRP R CH2 1 
ATOM   6359 N N   . VAL D 4 266 ? 159.567 170.120 193.344 1.00 124.18 ? 130 VAL R N   1 
ATOM   6360 C CA  . VAL D 4 266 ? 159.295 170.796 194.606 1.00 123.24 ? 130 VAL R CA  1 
ATOM   6361 C C   . VAL D 4 266 ? 158.077 170.150 195.250 1.00 123.48 ? 130 VAL R C   1 
ATOM   6362 O O   . VAL D 4 266 ? 157.012 170.069 194.629 1.00 123.13 ? 130 VAL R O   1 
ATOM   6363 C CB  . VAL D 4 266 ? 159.065 172.306 194.407 1.00 122.22 ? 130 VAL R CB  1 
ATOM   6364 N N   . HIS D 4 267 ? 158.231 169.705 196.495 1.00 122.47 ? 131 HIS R N   1 
ATOM   6365 C CA  . HIS D 4 267 ? 157.150 169.043 197.215 1.00 121.63 ? 131 HIS R CA  1 
ATOM   6366 C C   . HIS D 4 267 ? 156.429 169.955 198.195 1.00 121.85 ? 131 HIS R C   1 
ATOM   6367 O O   . HIS D 4 267 ? 155.245 169.734 198.468 1.00 121.67 ? 131 HIS R O   1 
ATOM   6368 C CB  . HIS D 4 267 ? 157.687 167.823 197.971 1.00 121.35 ? 131 HIS R CB  1 
ATOM   6369 N N   . HIS D 4 268 ? 157.111 170.964 198.738 1.00 122.28 ? 132 HIS R N   1 
ATOM   6370 C CA  . HIS D 4 268 ? 156.469 171.856 199.702 1.00 122.34 ? 132 HIS R CA  1 
ATOM   6371 C C   . HIS D 4 268 ? 155.302 172.639 199.107 1.00 122.74 ? 132 HIS R C   1 
ATOM   6372 O O   . HIS D 4 268 ? 154.224 172.653 199.725 1.00 122.13 ? 132 HIS R O   1 
ATOM   6373 C CB  . HIS D 4 268 ? 157.519 172.785 200.322 1.00 121.05 ? 132 HIS R CB  1 
ATOM   6374 N N   . PRO D 4 269 ? 155.422 173.296 197.953 1.00 120.78 ? 133 PRO R N   1 
ATOM   6375 C CA  . PRO D 4 269 ? 154.268 173.989 197.373 1.00 119.77 ? 133 PRO R CA  1 
ATOM   6376 C C   . PRO D 4 269 ? 153.356 173.002 196.651 1.00 120.54 ? 133 PRO R C   1 
ATOM   6377 O O   . PRO D 4 269 ? 153.558 171.790 196.679 1.00 120.51 ? 133 PRO R O   1 
ATOM   6378 C CB  . PRO D 4 269 ? 154.901 174.987 196.393 1.00 119.11 ? 133 PRO R CB  1 
ATOM   6379 C CG  . PRO D 4 269 ? 156.378 174.948 196.668 1.00 119.33 ? 133 PRO R CG  1 
ATOM   6380 C CD  . PRO D 4 269 ? 156.638 173.575 197.172 1.00 119.51 ? 133 PRO R CD  1 
ATOM   6381 N N   . TRP D 4 270 ? 152.331 173.549 196.001 1.00 116.59 ? 134 TRP R N   1 
ATOM   6382 C CA  . TRP D 4 270 ? 151.410 172.755 195.202 1.00 115.99 ? 134 TRP R CA  1 
ATOM   6383 C C   . TRP D 4 270 ? 150.995 173.552 193.975 1.00 115.45 ? 134 TRP R C   1 
ATOM   6384 O O   . TRP D 4 270 ? 151.072 174.782 193.950 1.00 114.40 ? 134 TRP R O   1 
ATOM   6385 C CB  . TRP D 4 270 ? 150.169 172.338 196.003 1.00 114.02 ? 134 TRP R CB  1 
ATOM   6386 N N   . ALA D 4 271 ? 150.557 172.828 192.947 1.00 116.47 ? 135 ALA R N   1 
ATOM   6387 C CA  . ALA D 4 271 ? 150.056 173.443 191.727 1.00 116.21 ? 135 ALA R CA  1 
ATOM   6388 C C   . ALA D 4 271 ? 148.556 173.698 191.765 1.00 115.65 ? 135 ALA R C   1 
ATOM   6389 O O   . ALA D 4 271 ? 148.039 174.390 190.881 1.00 115.47 ? 135 ALA R O   1 
ATOM   6390 C CB  . ALA D 4 271 ? 150.393 172.567 190.516 1.00 114.33 ? 135 ALA R CB  1 
ATOM   6391 N N   . PHE D 4 272 ? 147.851 173.163 192.758 1.00 113.22 ? 136 PHE R N   1 
ATOM   6392 C CA  . PHE D 4 272 ? 146.411 173.340 192.867 1.00 113.47 ? 136 PHE R CA  1 
ATOM   6393 C C   . PHE D 4 272 ? 146.025 173.289 194.339 1.00 114.06 ? 136 PHE R C   1 
ATOM   6394 O O   . PHE D 4 272 ? 146.873 173.127 195.221 1.00 113.67 ? 136 PHE R O   1 
ATOM   6395 C CB  . PHE D 4 272 ? 145.663 172.280 192.053 1.00 112.50 ? 136 PHE R CB  1 
ATOM   6396 N N   . GLY D 4 273 ? 144.728 173.427 194.600 1.00 113.96 ? 137 GLY R N   1 
ATOM   6397 C CA  . GLY D 4 273 ? 144.225 173.400 195.958 1.00 113.54 ? 137 GLY R CA  1 
ATOM   6398 C C   . GLY D 4 273 ? 143.638 172.059 196.341 1.00 113.36 ? 137 GLY R C   1 
ATOM   6399 O O   . GLY D 4 273 ? 144.375 171.103 196.601 1.00 113.13 ? 137 GLY R O   1 
ATOM   6400 N N   . ASP D 4 274 ? 142.311 171.975 196.383 1.00 111.70 ? 138 ASP R N   1 
ATOM   6401 C CA  . ASP D 4 274 ? 141.612 170.736 196.698 1.00 112.09 ? 138 ASP R CA  1 
ATOM   6402 C C   . ASP D 4 274 ? 140.895 170.132 195.503 1.00 112.03 ? 138 ASP R C   1 
ATOM   6403 O O   . ASP D 4 274 ? 140.822 168.908 195.389 1.00 112.01 ? 138 ASP R O   1 
ATOM   6404 C CB  . ASP D 4 274 ? 140.601 170.970 197.826 1.00 111.24 ? 138 ASP R CB  1 
ATOM   6405 N N   . ALA D 4 275 ? 140.355 170.964 194.610 1.00 113.84 ? 139 ALA R N   1 
ATOM   6406 C CA  . ALA D 4 275 ? 139.683 170.440 193.427 1.00 114.13 ? 139 ALA R CA  1 
ATOM   6407 C C   . ALA D 4 275 ? 140.684 169.924 192.401 1.00 114.90 ? 139 ALA R C   1 
ATOM   6408 O O   . ALA D 4 275 ? 140.466 168.874 191.786 1.00 114.23 ? 139 ALA R O   1 
ATOM   6409 C CB  . ALA D 4 275 ? 138.790 171.515 192.811 1.00 114.07 ? 139 ALA R CB  1 
ATOM   6410 N N   . GLY D 4 276 ? 141.785 170.650 192.200 1.00 116.26 ? 140 GLY R N   1 
ATOM   6411 C CA  . GLY D 4 276 ? 142.779 170.264 191.216 1.00 116.22 ? 140 GLY R CA  1 
ATOM   6412 C C   . GLY D 4 276 ? 143.753 169.196 191.660 1.00 115.94 ? 140 GLY R C   1 
ATOM   6413 O O   . GLY D 4 276 ? 144.441 168.617 190.814 1.00 114.99 ? 140 GLY R O   1 
ATOM   6414 N N   . CYS D 4 277 ? 143.831 168.924 192.961 1.00 112.55 ? 141 CYS R N   1 
ATOM   6415 C CA  . CYS D 4 277 ? 144.700 167.875 193.481 1.00 111.96 ? 141 CYS R CA  1 
ATOM   6416 C C   . CYS D 4 277 ? 143.969 166.541 193.578 1.00 112.11 ? 141 CYS R C   1 
ATOM   6417 O O   . CYS D 4 277 ? 144.469 165.511 193.107 1.00 111.26 ? 141 CYS R O   1 
ATOM   6418 C CB  . CYS D 4 277 ? 145.245 168.283 194.851 1.00 111.80 ? 141 CYS R CB  1 
ATOM   6419 S SG  . CYS D 4 277 ? 145.736 166.899 195.888 1.00 114.49 ? 141 CYS R SG  1 
ATOM   6420 N N   . ARG D 4 278 ? 142.783 166.549 194.190 1.00 110.18 ? 142 ARG R N   1 
ATOM   6421 C CA  . ARG D 4 278 ? 141.946 165.359 194.188 1.00 110.42 ? 142 ARG R CA  1 
ATOM   6422 C C   . ARG D 4 278 ? 141.569 164.956 192.771 1.00 109.30 ? 142 ARG R C   1 
ATOM   6423 O O   . ARG D 4 278 ? 141.546 163.763 192.455 1.00 110.37 ? 142 ARG R O   1 
ATOM   6424 C CB  . ARG D 4 278 ? 140.690 165.596 195.026 1.00 110.19 ? 142 ARG R CB  1 
ATOM   6425 N N   . GLY D 4 279 ? 141.280 165.930 191.908 1.00 104.82 ? 143 GLY R N   1 
ATOM   6426 C CA  . GLY D 4 279 ? 141.001 165.611 190.519 1.00 105.23 ? 143 GLY R CA  1 
ATOM   6427 C C   . GLY D 4 279 ? 142.184 164.971 189.820 1.00 106.37 ? 143 GLY R C   1 
ATOM   6428 O O   . GLY D 4 279 ? 142.022 164.023 189.050 1.00 106.48 ? 143 GLY R O   1 
ATOM   6429 N N   . TYR D 4 280 ? 143.392 165.474 190.087 1.00 106.63 ? 144 TYR R N   1 
ATOM   6430 C CA  . TYR D 4 280 ? 144.586 164.902 189.473 1.00 107.61 ? 144 TYR R CA  1 
ATOM   6431 C C   . TYR D 4 280 ? 144.811 163.468 189.935 1.00 106.26 ? 144 TYR R C   1 
ATOM   6432 O O   . TYR D 4 280 ? 145.105 162.578 189.125 1.00 105.16 ? 144 TYR R O   1 
ATOM   6433 C CB  . TYR D 4 280 ? 145.805 165.768 189.794 1.00 106.35 ? 144 TYR R CB  1 
ATOM   6434 N N   . TYR D 4 281 ? 144.683 163.223 191.241 1.00 100.16 ? 145 TYR R N   1 
ATOM   6435 C CA  . TYR D 4 281 ? 144.883 161.867 191.744 1.00 98.91  ? 145 TYR R CA  1 
ATOM   6436 C C   . TYR D 4 281 ? 143.801 160.922 191.236 1.00 99.06  ? 145 TYR R C   1 
ATOM   6437 O O   . TYR D 4 281 ? 144.086 159.763 190.916 1.00 101.44 ? 145 TYR R O   1 
ATOM   6438 C CB  . TYR D 4 281 ? 144.938 161.863 193.269 1.00 98.75  ? 145 TYR R CB  1 
ATOM   6439 C CG  . TYR D 4 281 ? 146.348 161.764 193.804 1.00 100.06 ? 145 TYR R CG  1 
ATOM   6440 C CD1 . TYR D 4 281 ? 147.411 162.325 193.110 1.00 100.48 ? 145 TYR R CD1 1 
ATOM   6441 C CD2 . TYR D 4 281 ? 146.618 161.105 194.995 1.00 99.83  ? 145 TYR R CD2 1 
ATOM   6442 C CE1 . TYR D 4 281 ? 148.702 162.239 193.589 1.00 100.44 ? 145 TYR R CE1 1 
ATOM   6443 C CE2 . TYR D 4 281 ? 147.908 161.015 195.483 1.00 99.36  ? 145 TYR R CE2 1 
ATOM   6444 C CZ  . TYR D 4 281 ? 148.946 161.584 194.776 1.00 100.85 ? 145 TYR R CZ  1 
ATOM   6445 O OH  . TYR D 4 281 ? 150.233 161.498 195.255 1.00 100.55 ? 145 TYR R OH  1 
ATOM   6446 N N   . PHE D 4 282 ? 142.557 161.398 191.148 1.00 99.12  ? 146 PHE R N   1 
ATOM   6447 C CA  . PHE D 4 282 ? 141.490 160.581 190.581 1.00 98.92  ? 146 PHE R CA  1 
ATOM   6448 C C   . PHE D 4 282 ? 141.764 160.255 189.119 1.00 99.65  ? 146 PHE R C   1 
ATOM   6449 O O   . PHE D 4 282 ? 141.543 159.122 188.679 1.00 100.20 ? 146 PHE R O   1 
ATOM   6450 C CB  . PHE D 4 282 ? 140.149 161.298 190.732 1.00 101.21 ? 146 PHE R CB  1 
ATOM   6451 C CG  . PHE D 4 282 ? 139.060 160.748 189.857 1.00 100.14 ? 146 PHE R CG  1 
ATOM   6452 C CD1 . PHE D 4 282 ? 138.495 159.514 190.123 1.00 99.67  ? 146 PHE R CD1 1 
ATOM   6453 C CD2 . PHE D 4 282 ? 138.591 161.473 188.775 1.00 100.16 ? 146 PHE R CD2 1 
ATOM   6454 C CE1 . PHE D 4 282 ? 137.490 159.009 189.321 1.00 100.06 ? 146 PHE R CE1 1 
ATOM   6455 C CE2 . PHE D 4 282 ? 137.587 160.975 187.969 1.00 99.72  ? 146 PHE R CE2 1 
ATOM   6456 C CZ  . PHE D 4 282 ? 137.036 159.742 188.242 1.00 100.11 ? 146 PHE R CZ  1 
ATOM   6457 N N   . LEU D 4 283 ? 142.248 161.235 188.351 1.00 97.62  ? 147 LEU R N   1 
ATOM   6458 C CA  . LEU D 4 283 ? 142.569 160.986 186.950 1.00 98.18  ? 147 LEU R CA  1 
ATOM   6459 C C   . LEU D 4 283 ? 143.685 159.958 186.811 1.00 98.89  ? 147 LEU R C   1 
ATOM   6460 O O   . LEU D 4 283 ? 143.600 159.048 185.980 1.00 99.91  ? 147 LEU R O   1 
ATOM   6461 C CB  . LEU D 4 283 ? 142.957 162.295 186.262 1.00 95.77  ? 147 LEU R CB  1 
ATOM   6462 N N   . ARG D 4 284 ? 144.735 160.079 187.627 1.00 91.73  ? 148 ARG R N   1 
ATOM   6463 C CA  . ARG D 4 284 ? 145.842 159.129 187.547 1.00 89.70  ? 148 ARG R CA  1 
ATOM   6464 C C   . ARG D 4 284 ? 145.409 157.727 187.966 1.00 89.44  ? 148 ARG R C   1 
ATOM   6465 O O   . ARG D 4 284 ? 145.803 156.733 187.338 1.00 89.57  ? 148 ARG R O   1 
ATOM   6466 C CB  . ARG D 4 284 ? 147.008 159.625 188.403 1.00 90.15  ? 148 ARG R CB  1 
ATOM   6467 C CG  . ARG D 4 284 ? 147.763 158.547 189.155 1.00 88.76  ? 148 ARG R CG  1 
ATOM   6468 C CD  . ARG D 4 284 ? 149.215 158.951 189.332 1.00 89.26  ? 148 ARG R CD  1 
ATOM   6469 N NE  . ARG D 4 284 ? 149.891 158.159 190.352 1.00 89.06  ? 148 ARG R NE  1 
ATOM   6470 C CZ  . ARG D 4 284 ? 151.194 158.207 190.591 1.00 90.56  ? 148 ARG R CZ  1 
ATOM   6471 N NH1 . ARG D 4 284 ? 151.997 158.987 189.886 1.00 90.69  ? 148 ARG R NH1 1 
ATOM   6472 N NH2 . ARG D 4 284 ? 151.703 157.458 191.563 1.00 90.10  ? 148 ARG R NH2 1 
ATOM   6473 N N   . ASP D 4 285 ? 144.599 157.623 189.024 1.00 93.10  ? 149 ASP R N   1 
ATOM   6474 C CA  . ASP D 4 285 ? 144.105 156.319 189.453 1.00 91.11  ? 149 ASP R CA  1 
ATOM   6475 C C   . ASP D 4 285 ? 143.204 155.696 188.395 1.00 91.99  ? 149 ASP R C   1 
ATOM   6476 O O   . ASP D 4 285 ? 143.294 154.494 188.123 1.00 92.67  ? 149 ASP R O   1 
ATOM   6477 C CB  . ASP D 4 285 ? 143.367 156.450 190.784 1.00 91.30  ? 149 ASP R CB  1 
ATOM   6478 N N   . ALA D 4 286 ? 142.328 156.497 187.785 1.00 95.93  ? 150 ALA R N   1 
ATOM   6479 C CA  . ALA D 4 286 ? 141.495 155.987 186.704 1.00 95.15  ? 150 ALA R CA  1 
ATOM   6480 C C   . ALA D 4 286 ? 142.346 155.541 185.525 1.00 96.40  ? 150 ALA R C   1 
ATOM   6481 O O   . ALA D 4 286 ? 142.033 154.544 184.868 1.00 97.56  ? 150 ALA R O   1 
ATOM   6482 C CB  . ALA D 4 286 ? 140.488 157.049 186.269 1.00 96.02  ? 150 ALA R CB  1 
ATOM   6483 N N   . CYS D 4 287 ? 143.434 156.262 185.247 1.00 96.59  ? 151 CYS R N   1 
ATOM   6484 C CA  . CYS D 4 287 ? 144.312 155.884 184.145 1.00 96.29  ? 151 CYS R CA  1 
ATOM   6485 C C   . CYS D 4 287 ? 144.999 154.548 184.406 1.00 96.32  ? 151 CYS R C   1 
ATOM   6486 O O   . CYS D 4 287 ? 145.059 153.692 183.515 1.00 98.62  ? 151 CYS R O   1 
ATOM   6487 C CB  . CYS D 4 287 ? 145.345 156.982 183.901 1.00 96.67  ? 151 CYS R CB  1 
ATOM   6488 S SG  . CYS D 4 287 ? 144.761 158.318 182.835 1.00 101.60 ? 151 CYS R SG  1 
ATOM   6489 N N   . THR D 4 288 ? 145.529 154.346 185.616 1.00 91.90  ? 152 THR R N   1 
ATOM   6490 C CA  . THR D 4 288 ? 146.188 153.070 185.888 1.00 91.58  ? 152 THR R CA  1 
ATOM   6491 C C   . THR D 4 288 ? 145.177 151.927 185.934 1.00 91.77  ? 152 THR R C   1 
ATOM   6492 O O   . THR D 4 288 ? 145.468 150.817 185.468 1.00 91.86  ? 152 THR R O   1 
ATOM   6493 C CB  . THR D 4 288 ? 147.010 153.127 187.180 1.00 91.50  ? 152 THR R CB  1 
ATOM   6494 O OG1 . THR D 4 288 ? 147.488 151.815 187.497 1.00 92.85  ? 152 THR R OG1 1 
ATOM   6495 C CG2 . THR D 4 288 ? 146.191 153.636 188.339 1.00 91.97  ? 152 THR R CG2 1 
ATOM   6496 N N   . TYR D 4 289 ? 143.976 152.184 186.464 1.00 95.26  ? 153 TYR R N   1 
ATOM   6497 C CA  . TYR D 4 289 ? 142.923 151.174 186.421 1.00 95.04  ? 153 TYR R CA  1 
ATOM   6498 C C   . TYR D 4 289 ? 142.565 150.817 184.985 1.00 94.97  ? 153 TYR R C   1 
ATOM   6499 O O   . TYR D 4 289 ? 142.378 149.639 184.660 1.00 95.09  ? 153 TYR R O   1 
ATOM   6500 C CB  . TYR D 4 289 ? 141.681 151.666 187.164 1.00 95.70  ? 153 TYR R CB  1 
ATOM   6501 C CG  . TYR D 4 289 ? 141.685 151.385 188.648 1.00 95.51  ? 153 TYR R CG  1 
ATOM   6502 C CD1 . TYR D 4 289 ? 141.713 150.083 189.127 1.00 94.91  ? 153 TYR R CD1 1 
ATOM   6503 C CD2 . TYR D 4 289 ? 141.637 152.420 189.570 1.00 95.61  ? 153 TYR R CD2 1 
ATOM   6504 C CE1 . TYR D 4 289 ? 141.709 149.821 190.482 1.00 95.70  ? 153 TYR R CE1 1 
ATOM   6505 C CE2 . TYR D 4 289 ? 141.634 152.168 190.926 1.00 95.68  ? 153 TYR R CE2 1 
ATOM   6506 C CZ  . TYR D 4 289 ? 141.669 150.867 191.376 1.00 96.25  ? 153 TYR R CZ  1 
ATOM   6507 O OH  . TYR D 4 289 ? 141.663 150.613 192.726 1.00 96.27  ? 153 TYR R OH  1 
ATOM   6508 N N   . ALA D 4 290 ? 142.460 151.822 184.113 1.00 91.79  ? 154 ALA R N   1 
ATOM   6509 C CA  . ALA D 4 290 ? 142.132 151.566 182.717 1.00 91.25  ? 154 ALA R CA  1 
ATOM   6510 C C   . ALA D 4 290 ? 143.226 150.762 182.031 1.00 92.78  ? 154 ALA R C   1 
ATOM   6511 O O   . ALA D 4 290 ? 142.934 149.846 181.258 1.00 93.15  ? 154 ALA R O   1 
ATOM   6512 C CB  . ALA D 4 290 ? 141.894 152.884 181.983 1.00 90.87  ? 154 ALA R CB  1 
ATOM   6513 N N   . THR D 4 291 ? 144.494 151.090 182.297 1.00 94.51  ? 155 THR R N   1 
ATOM   6514 C CA  . THR D 4 291 ? 145.585 150.335 181.687 1.00 93.42  ? 155 THR R CA  1 
ATOM   6515 C C   . THR D 4 291 ? 145.579 148.884 182.150 1.00 93.58  ? 155 THR R C   1 
ATOM   6516 O O   . THR D 4 291 ? 145.728 147.963 181.335 1.00 94.63  ? 155 THR R O   1 
ATOM   6517 C CB  . THR D 4 291 ? 146.931 150.981 182.006 1.00 91.44  ? 155 THR R CB  1 
ATOM   6518 O OG1 . THR D 4 291 ? 146.985 151.308 183.398 1.00 93.02  ? 155 THR R OG1 1 
ATOM   6519 C CG2 . THR D 4 291 ? 147.124 152.242 181.185 1.00 92.41  ? 155 THR R CG2 1 
ATOM   6520 N N   . ALA D 4 292 ? 145.401 148.657 183.455 1.00 90.78  ? 156 ALA R N   1 
ATOM   6521 C CA  . ALA D 4 292 ? 145.362 147.289 183.962 1.00 90.58  ? 156 ALA R CA  1 
ATOM   6522 C C   . ALA D 4 292 ? 144.180 146.519 183.386 1.00 90.60  ? 156 ALA R C   1 
ATOM   6523 O O   . ALA D 4 292 ? 144.324 145.361 182.972 1.00 92.01  ? 156 ALA R O   1 
ATOM   6524 C CB  . ALA D 4 292 ? 145.305 147.297 185.489 1.00 93.01  ? 156 ALA R CB  1 
ATOM   6525 N N   . LEU D 4 293 ? 143.004 147.149 183.344 1.00 87.02  ? 157 LEU R N   1 
ATOM   6526 C CA  . LEU D 4 293 ? 141.821 146.485 182.811 1.00 89.23  ? 157 LEU R CA  1 
ATOM   6527 C C   . LEU D 4 293 ? 141.990 146.173 181.331 1.00 90.64  ? 157 LEU R C   1 
ATOM   6528 O O   . LEU D 4 293 ? 141.590 145.104 180.865 1.00 89.98  ? 157 LEU R O   1 
ATOM   6529 C CB  . LEU D 4 293 ? 140.584 147.353 183.044 1.00 89.28  ? 157 LEU R CB  1 
ATOM   6530 N N   . ASN D 4 294 ? 142.577 147.102 180.573 1.00 89.35  ? 158 ASN R N   1 
ATOM   6531 C CA  . ASN D 4 294 ? 142.793 146.873 179.150 1.00 88.63  ? 158 ASN R CA  1 
ATOM   6532 C C   . ASN D 4 294 ? 143.782 145.738 178.914 1.00 90.33  ? 158 ASN R C   1 
ATOM   6533 O O   . ASN D 4 294 ? 143.569 144.903 178.029 1.00 90.45  ? 158 ASN R O   1 
ATOM   6534 C CB  . ASN D 4 294 ? 143.275 148.159 178.480 1.00 86.53  ? 158 ASN R CB  1 
ATOM   6535 N N   . VAL D 4 295 ? 144.862 145.684 179.699 1.00 87.87  ? 159 VAL R N   1 
ATOM   6536 C CA  . VAL D 4 295 ? 145.828 144.595 179.558 1.00 85.83  ? 159 VAL R CA  1 
ATOM   6537 C C   . VAL D 4 295 ? 145.168 143.257 179.875 1.00 87.17  ? 159 VAL R C   1 
ATOM   6538 O O   . VAL D 4 295 ? 145.322 142.274 179.137 1.00 88.01  ? 159 VAL R O   1 
ATOM   6539 C CB  . VAL D 4 295 ? 147.053 144.844 180.456 1.00 85.12  ? 159 VAL R CB  1 
ATOM   6540 C CG1 . VAL D 4 295 ? 147.830 143.556 180.667 1.00 85.98  ? 159 VAL R CG1 1 
ATOM   6541 C CG2 . VAL D 4 295 ? 147.945 145.910 179.852 1.00 86.72  ? 159 VAL R CG2 1 
ATOM   6542 N N   . ALA D 4 296 ? 144.412 143.204 180.975 1.00 91.44  ? 160 ALA R N   1 
ATOM   6543 C CA  . ALA D 4 296 ? 143.750 141.961 181.353 1.00 91.28  ? 160 ALA R CA  1 
ATOM   6544 C C   . ALA D 4 296 ? 142.720 141.542 180.313 1.00 93.39  ? 160 ALA R C   1 
ATOM   6545 O O   . ALA D 4 296 ? 142.597 140.355 179.992 1.00 95.78  ? 160 ALA R O   1 
ATOM   6546 C CB  . ALA D 4 296 ? 143.097 142.111 182.726 1.00 92.88  ? 160 ALA R CB  1 
ATOM   6547 N N   . SER D 4 297 ? 141.971 142.502 179.770 1.00 96.33  ? 161 SER R N   1 
ATOM   6548 C CA  . SER D 4 297 ? 140.950 142.183 178.779 1.00 96.35  ? 161 SER R CA  1 
ATOM   6549 C C   . SER D 4 297 ? 141.577 141.723 177.473 1.00 95.54  ? 161 SER R C   1 
ATOM   6550 O O   . SER D 4 297 ? 141.046 140.833 176.802 1.00 96.38  ? 161 SER R O   1 
ATOM   6551 C CB  . SER D 4 297 ? 140.060 143.399 178.551 1.00 95.54  ? 161 SER R CB  1 
ATOM   6552 O OG  . SER D 4 297 ? 139.275 143.651 179.699 1.00 97.81  ? 161 SER R OG  1 
ATOM   6553 N N   . LEU D 4 298 ? 142.706 142.323 177.093 1.00 94.38  ? 162 LEU R N   1 
ATOM   6554 C CA  . LEU D 4 298 ? 143.436 141.864 175.920 1.00 94.10  ? 162 LEU R CA  1 
ATOM   6555 C C   . LEU D 4 298 ? 143.940 140.440 176.113 1.00 93.27  ? 162 LEU R C   1 
ATOM   6556 O O   . LEU D 4 298 ? 143.864 139.615 175.194 1.00 94.49  ? 162 LEU R O   1 
ATOM   6557 C CB  . LEU D 4 298 ? 144.592 142.820 175.638 1.00 94.05  ? 162 LEU R CB  1 
ATOM   6558 C CG  . LEU D 4 298 ? 145.667 142.403 174.643 1.00 93.55  ? 162 LEU R CG  1 
ATOM   6559 C CD1 . LEU D 4 298 ? 145.073 142.236 173.257 1.00 95.23  ? 162 LEU R CD1 1 
ATOM   6560 C CD2 . LEU D 4 298 ? 146.773 143.441 174.647 1.00 93.54  ? 162 LEU R CD2 1 
ATOM   6561 N N   . SER D 4 299 ? 144.452 140.132 177.308 1.00 96.28  ? 163 SER R N   1 
ATOM   6562 C CA  . SER D 4 299 ? 144.877 138.764 177.592 1.00 97.19  ? 163 SER R CA  1 
ATOM   6563 C C   . SER D 4 299 ? 143.700 137.799 177.529 1.00 96.79  ? 163 SER R C   1 
ATOM   6564 O O   . SER D 4 299 ? 143.827 136.686 177.008 1.00 98.25  ? 163 SER R O   1 
ATOM   6565 C CB  . SER D 4 299 ? 145.558 138.695 178.959 1.00 97.39  ? 163 SER R CB  1 
ATOM   6566 O OG  . SER D 4 299 ? 144.623 138.874 180.006 1.00 99.41  ? 163 SER R OG  1 
ATOM   6567 N N   . VAL D 4 300 ? 142.544 138.213 178.053 1.00 96.19  ? 164 VAL R N   1 
ATOM   6568 C CA  . VAL D 4 300 ? 141.350 137.371 178.002 1.00 97.60  ? 164 VAL R CA  1 
ATOM   6569 C C   . VAL D 4 300 ? 140.933 137.121 176.558 1.00 97.33  ? 164 VAL R C   1 
ATOM   6570 O O   . VAL D 4 300 ? 140.590 135.993 176.180 1.00 97.17  ? 164 VAL R O   1 
ATOM   6571 C CB  . VAL D 4 300 ? 140.211 138.015 178.817 1.00 97.65  ? 164 VAL R CB  1 
ATOM   6572 C CG1 . VAL D 4 300 ? 138.868 137.399 178.452 1.00 97.25  ? 164 VAL R CG1 1 
ATOM   6573 C CG2 . VAL D 4 300 ? 140.478 137.875 180.306 1.00 95.78  ? 164 VAL R CG2 1 
ATOM   6574 N N   . GLU D 4 301 ? 140.949 138.169 175.733 1.00 97.91  ? 165 GLU R N   1 
ATOM   6575 C CA  . GLU D 4 301 ? 140.570 138.021 174.332 1.00 97.17  ? 165 GLU R CA  1 
ATOM   6576 C C   . GLU D 4 301 ? 141.525 137.093 173.595 1.00 99.14  ? 165 GLU R C   1 
ATOM   6577 O O   . GLU D 4 301 ? 141.090 136.253 172.798 1.00 100.98 ? 165 GLU R O   1 
ATOM   6578 C CB  . GLU D 4 301 ? 140.521 139.390 173.655 1.00 95.45  ? 165 GLU R CB  1 
ATOM   6579 N N   . ARG D 4 302 ? 142.831 137.231 173.838 1.00 99.77  ? 166 ARG R N   1 
ATOM   6580 C CA  . ARG D 4 302 ? 143.790 136.344 173.185 1.00 98.50  ? 166 ARG R CA  1 
ATOM   6581 C C   . ARG D 4 302 ? 143.611 134.903 173.647 1.00 99.89  ? 166 ARG R C   1 
ATOM   6582 O O   . ARG D 4 302 ? 143.693 133.972 172.836 1.00 100.94 ? 166 ARG R O   1 
ATOM   6583 C CB  . ARG D 4 302 ? 145.217 136.822 173.442 1.00 98.38  ? 166 ARG R CB  1 
ATOM   6584 C CG  . ARG D 4 302 ? 145.519 138.194 172.864 1.00 99.67  ? 166 ARG R CG  1 
ATOM   6585 C CD  . ARG D 4 302 ? 145.040 138.316 171.428 1.00 98.70  ? 166 ARG R CD  1 
ATOM   6586 N NE  . ARG D 4 302 ? 145.638 137.311 170.558 1.00 98.63  ? 166 ARG R NE  1 
ATOM   6587 C CZ  . ARG D 4 302 ? 145.170 136.983 169.362 1.00 100.18 ? 166 ARG R CZ  1 
ATOM   6588 N NH1 . ARG D 4 302 ? 144.089 137.559 168.861 1.00 101.30 ? 166 ARG R NH1 1 
ATOM   6589 N NH2 . ARG D 4 302 ? 145.802 136.056 168.649 1.00 99.88  ? 166 ARG R NH2 1 
ATOM   6590 N N   . TYR D 4 303 ? 143.370 134.701 174.946 1.00 102.90 ? 167 TYR R N   1 
ATOM   6591 C CA  . TYR D 4 303 ? 143.037 133.376 175.458 1.00 102.53 ? 167 TYR R CA  1 
ATOM   6592 C C   . TYR D 4 303 ? 141.854 132.780 174.711 1.00 103.89 ? 167 TYR R C   1 
ATOM   6593 O O   . TYR D 4 303 ? 141.922 131.653 174.205 1.00 105.34 ? 167 TYR R O   1 
ATOM   6594 C CB  . TYR D 4 303 ? 142.722 133.468 176.952 1.00 101.95 ? 167 TYR R CB  1 
ATOM   6595 C CG  . TYR D 4 303 ? 142.828 132.164 177.710 1.00 102.69 ? 167 TYR R CG  1 
ATOM   6596 C CD1 . TYR D 4 303 ? 143.294 131.010 177.100 1.00 102.87 ? 167 TYR R CD1 1 
ATOM   6597 C CD2 . TYR D 4 303 ? 142.405 132.078 179.026 1.00 102.40 ? 167 TYR R CD2 1 
ATOM   6598 C CE1 . TYR D 4 303 ? 143.371 129.818 177.794 1.00 101.50 ? 167 TYR R CE1 1 
ATOM   6599 C CE2 . TYR D 4 303 ? 142.477 130.895 179.725 1.00 102.93 ? 167 TYR R CE2 1 
ATOM   6600 C CZ  . TYR D 4 303 ? 142.959 129.768 179.107 1.00 103.16 ? 167 TYR R CZ  1 
ATOM   6601 O OH  . TYR D 4 303 ? 143.026 128.588 179.809 1.00 103.04 ? 167 TYR R OH  1 
ATOM   6602 N N   . LEU D 4 304 ? 140.759 133.536 174.625 1.00 102.82 ? 168 LEU R N   1 
ATOM   6603 C CA  . LEU D 4 304 ? 139.549 133.025 173.993 1.00 103.73 ? 168 LEU R CA  1 
ATOM   6604 C C   . LEU D 4 304 ? 139.780 132.726 172.519 1.00 104.22 ? 168 LEU R C   1 
ATOM   6605 O O   . LEU D 4 304 ? 139.293 131.717 171.999 1.00 106.11 ? 168 LEU R O   1 
ATOM   6606 C CB  . LEU D 4 304 ? 138.409 134.028 174.167 1.00 103.14 ? 168 LEU R CB  1 
ATOM   6607 C CG  . LEU D 4 304 ? 137.804 134.094 175.569 1.00 102.89 ? 168 LEU R CG  1 
ATOM   6608 C CD1 . LEU D 4 304 ? 136.656 135.088 175.611 1.00 103.18 ? 168 LEU R CD1 1 
ATOM   6609 C CD2 . LEU D 4 304 ? 137.348 132.716 176.027 1.00 102.92 ? 168 LEU R CD2 1 
ATOM   6610 N N   . ALA D 4 305 ? 140.526 133.587 171.829 1.00 104.10 ? 169 ALA R N   1 
ATOM   6611 C CA  . ALA D 4 305 ? 140.729 133.396 170.399 1.00 105.01 ? 169 ALA R CA  1 
ATOM   6612 C C   . ALA D 4 305 ? 141.634 132.204 170.110 1.00 105.61 ? 169 ALA R C   1 
ATOM   6613 O O   . ALA D 4 305 ? 141.365 131.429 169.185 1.00 105.64 ? 169 ALA R O   1 
ATOM   6614 C CB  . ALA D 4 305 ? 141.301 134.669 169.777 1.00 105.17 ? 169 ALA R CB  1 
ATOM   6615 N N   . LEU D 4 306 ? 142.707 132.031 170.886 1.00 103.32 ? 170 LEU R N   1 
ATOM   6616 C CA  . LEU D 4 306 ? 143.724 131.041 170.556 1.00 102.25 ? 170 LEU R CA  1 
ATOM   6617 C C   . LEU D 4 306 ? 143.568 129.714 171.288 1.00 103.32 ? 170 LEU R C   1 
ATOM   6618 O O   . LEU D 4 306 ? 144.294 128.768 170.966 1.00 104.17 ? 170 LEU R O   1 
ATOM   6619 C CB  . LEU D 4 306 ? 145.120 131.604 170.842 1.00 101.39 ? 170 LEU R CB  1 
ATOM   6620 C CG  . LEU D 4 306 ? 145.488 132.875 170.082 1.00 102.57 ? 170 LEU R CG  1 
ATOM   6621 C CD1 . LEU D 4 306 ? 146.404 133.735 170.928 1.00 103.63 ? 170 LEU R CD1 1 
ATOM   6622 C CD2 . LEU D 4 306 ? 146.139 132.538 168.750 1.00 101.91 ? 170 LEU R CD2 1 
ATOM   6623 N N   . CYS D 4 307 ? 142.661 129.608 172.252 1.00 108.66 ? 171 CYS R N   1 
ATOM   6624 C CA  . CYS D 4 307 ? 142.524 128.354 172.984 1.00 110.22 ? 171 CYS R CA  1 
ATOM   6625 C C   . CYS D 4 307 ? 141.154 127.712 172.851 1.00 110.57 ? 171 CYS R C   1 
ATOM   6626 O O   . CYS D 4 307 ? 141.067 126.500 172.635 1.00 109.92 ? 171 CYS R O   1 
ATOM   6627 C CB  . CYS D 4 307 ? 142.849 128.578 174.466 1.00 109.18 ? 171 CYS R CB  1 
ATOM   6628 S SG  . CYS D 4 307 ? 144.601 128.897 174.764 1.00 110.14 ? 171 CYS R SG  1 
ATOM   6629 N N   . HIS D 4 308 ? 140.076 128.484 172.975 1.00 115.20 ? 172 HIS R N   1 
ATOM   6630 C CA  . HIS D 4 308 ? 138.712 127.973 172.845 1.00 115.13 ? 172 HIS R CA  1 
ATOM   6631 C C   . HIS D 4 308 ? 138.049 128.924 171.856 1.00 116.24 ? 172 HIS R C   1 
ATOM   6632 O O   . HIS D 4 308 ? 137.327 129.852 172.248 1.00 116.56 ? 172 HIS R O   1 
ATOM   6633 C CB  . HIS D 4 308 ? 138.027 127.904 174.217 1.00 115.81 ? 172 HIS R CB  1 
ATOM   6634 C CG  . HIS D 4 308 ? 138.699 127.021 175.228 1.00 117.76 ? 172 HIS R CG  1 
ATOM   6635 N ND1 . HIS D 4 308 ? 138.721 125.649 175.095 1.00 118.41 ? 172 HIS R ND1 1 
ATOM   6636 C CD2 . HIS D 4 308 ? 139.308 127.289 176.408 1.00 116.47 ? 172 HIS R CD2 1 
ATOM   6637 C CE1 . HIS D 4 308 ? 139.355 125.116 176.125 1.00 117.11 ? 172 HIS R CE1 1 
ATOM   6638 N NE2 . HIS D 4 308 ? 139.721 126.091 176.936 1.00 116.68 ? 172 HIS R NE2 1 
ATOM   6639 N N   . PRO D 4 309 ? 138.321 128.755 170.558 1.00 117.12 ? 173 PRO R N   1 
ATOM   6640 C CA  . PRO D 4 309 ? 137.814 129.722 169.567 1.00 116.90 ? 173 PRO R CA  1 
ATOM   6641 C C   . PRO D 4 309 ? 136.299 129.783 169.479 1.00 116.96 ? 173 PRO R C   1 
ATOM   6642 O O   . PRO D 4 309 ? 135.756 130.813 169.056 1.00 116.66 ? 173 PRO R O   1 
ATOM   6643 C CB  . PRO D 4 309 ? 138.432 129.228 168.249 1.00 116.02 ? 173 PRO R CB  1 
ATOM   6644 C CG  . PRO D 4 309 ? 139.581 128.360 168.657 1.00 115.45 ? 173 PRO R CG  1 
ATOM   6645 C CD  . PRO D 4 309 ? 139.158 127.716 169.936 1.00 115.63 ? 173 PRO R CD  1 
ATOM   6646 N N   . PHE D 4 310 ? 135.600 128.711 169.858 1.00 116.56 ? 174 PHE R N   1 
ATOM   6647 C CA  . PHE D 4 310 ? 134.147 128.695 169.736 1.00 116.43 ? 174 PHE R CA  1 
ATOM   6648 C C   . PHE D 4 310 ? 133.502 129.765 170.609 1.00 117.22 ? 174 PHE R C   1 
ATOM   6649 O O   . PHE D 4 310 ? 132.557 130.437 170.182 1.00 117.17 ? 174 PHE R O   1 
ATOM   6650 C CB  . PHE D 4 310 ? 133.607 127.311 170.095 1.00 115.00 ? 174 PHE R CB  1 
ATOM   6651 N N   . LYS D 4 311 ? 133.995 129.933 171.839 1.00 116.18 ? 175 LYS R N   1 
ATOM   6652 C CA  . LYS D 4 311 ? 133.416 130.928 172.737 1.00 116.11 ? 175 LYS R CA  1 
ATOM   6653 C C   . LYS D 4 311 ? 133.611 132.339 172.200 1.00 115.86 ? 175 LYS R C   1 
ATOM   6654 O O   . LYS D 4 311 ? 132.692 133.165 172.256 1.00 114.69 ? 175 LYS R O   1 
ATOM   6655 C CB  . LYS D 4 311 ? 134.027 130.799 174.131 1.00 115.14 ? 175 LYS R CB  1 
ATOM   6656 N N   . ALA D 4 312 ? 134.805 132.638 171.685 1.00 115.51 ? 176 ALA R N   1 
ATOM   6657 C CA  . ALA D 4 312 ? 135.059 133.965 171.136 1.00 116.45 ? 176 ALA R CA  1 
ATOM   6658 C C   . ALA D 4 312 ? 134.225 134.218 169.887 1.00 117.88 ? 176 ALA R C   1 
ATOM   6659 O O   . ALA D 4 312 ? 133.684 135.315 169.709 1.00 118.20 ? 176 ALA R O   1 
ATOM   6660 C CB  . ALA D 4 312 ? 136.547 134.132 170.833 1.00 116.06 ? 176 ALA R CB  1 
ATOM   6661 N N   . LYS D 4 313 ? 134.113 133.221 169.006 1.00 118.63 ? 177 LYS R N   1 
ATOM   6662 C CA  . LYS D 4 313 ? 133.340 133.406 167.782 1.00 116.98 ? 177 LYS R CA  1 
ATOM   6663 C C   . LYS D 4 313 ? 131.855 133.572 168.080 1.00 118.03 ? 177 LYS R C   1 
ATOM   6664 O O   . LYS D 4 313 ? 131.191 134.435 167.494 1.00 118.63 ? 177 LYS R O   1 
ATOM   6665 C CB  . LYS D 4 313 ? 133.568 132.230 166.833 1.00 116.39 ? 177 LYS R CB  1 
ATOM   6666 N N   . THR D 4 314 ? 131.316 132.757 168.989 1.00 116.33 ? 178 THR R N   1 
ATOM   6667 C CA  . THR D 4 314 ? 129.882 132.776 169.256 1.00 117.05 ? 178 THR R CA  1 
ATOM   6668 C C   . THR D 4 314 ? 129.471 133.970 170.112 1.00 118.16 ? 178 THR R C   1 
ATOM   6669 O O   . THR D 4 314 ? 128.406 134.556 169.889 1.00 117.45 ? 178 THR R O   1 
ATOM   6670 C CB  . THR D 4 314 ? 129.459 131.472 169.933 1.00 115.13 ? 178 THR R CB  1 
ATOM   6671 N N   . LEU D 4 315 ? 130.293 134.345 171.091 1.00 117.82 ? 179 LEU R N   1 
ATOM   6672 C CA  . LEU D 4 315 ? 129.931 135.373 172.059 1.00 116.57 ? 179 LEU R CA  1 
ATOM   6673 C C   . LEU D 4 315 ? 130.663 136.689 171.846 1.00 115.99 ? 179 LEU R C   1 
ATOM   6674 O O   . LEU D 4 315 ? 130.035 137.752 171.860 1.00 116.12 ? 179 LEU R O   1 
ATOM   6675 C CB  . LEU D 4 315 ? 130.192 134.861 173.484 1.00 114.84 ? 179 LEU R CB  1 
ATOM   6676 N N   . MET D 4 316 ? 131.978 136.651 171.645 1.00 114.47 ? 180 MET R N   1 
ATOM   6677 C CA  . MET D 4 316 ? 132.785 137.869 171.565 1.00 113.66 ? 180 MET R CA  1 
ATOM   6678 C C   . MET D 4 316 ? 132.688 138.443 170.157 1.00 115.01 ? 180 MET R C   1 
ATOM   6679 O O   . MET D 4 316 ? 133.427 138.060 169.249 1.00 115.25 ? 180 MET R O   1 
ATOM   6680 C CB  . MET D 4 316 ? 134.230 137.579 171.952 1.00 113.17 ? 180 MET R CB  1 
ATOM   6681 N N   . SER D 4 317 ? 131.768 139.384 169.976 1.00 113.19 ? 181 SER R N   1 
ATOM   6682 C CA  . SER D 4 317 ? 131.594 140.090 168.716 1.00 113.23 ? 181 SER R CA  1 
ATOM   6683 C C   . SER D 4 317 ? 132.101 141.521 168.848 1.00 111.63 ? 181 SER R C   1 
ATOM   6684 O O   . SER D 4 317 ? 132.481 141.975 169.930 1.00 111.50 ? 181 SER R O   1 
ATOM   6685 C CB  . SER D 4 317 ? 130.123 140.077 168.281 1.00 112.93 ? 181 SER R CB  1 
ATOM   6686 O OG  . SER D 4 317 ? 129.312 140.786 169.199 1.00 111.55 ? 181 SER R OG  1 
ATOM   6687 N N   . ARG D 4 318 ? 132.111 142.231 167.716 1.00 106.93 ? 182 ARG R N   1 
ATOM   6688 C CA  . ARG D 4 318 ? 132.596 143.608 167.715 1.00 107.91 ? 182 ARG R CA  1 
ATOM   6689 C C   . ARG D 4 318 ? 131.709 144.512 168.561 1.00 108.16 ? 182 ARG R C   1 
ATOM   6690 O O   . ARG D 4 318 ? 132.210 145.371 169.294 1.00 108.32 ? 182 ARG R O   1 
ATOM   6691 C CB  . ARG D 4 318 ? 132.689 144.133 166.283 1.00 107.68 ? 182 ARG R CB  1 
ATOM   6692 C CG  . ARG D 4 318 ? 132.912 143.052 165.246 1.00 107.33 ? 182 ARG R CG  1 
ATOM   6693 C CD  . ARG D 4 318 ? 134.388 142.894 164.926 1.00 106.74 ? 182 ARG R CD  1 
ATOM   6694 N NE  . ARG D 4 318 ? 135.059 144.179 164.774 1.00 106.58 ? 182 ARG R NE  1 
ATOM   6695 C CZ  . ARG D 4 318 ? 135.328 144.748 163.607 1.00 107.14 ? 182 ARG R CZ  1 
ATOM   6696 N NH1 . ARG D 4 318 ? 134.994 144.173 162.464 1.00 105.50 ? 182 ARG R NH1 1 
ATOM   6697 N NH2 . ARG D 4 318 ? 135.951 145.923 163.586 1.00 107.57 ? 182 ARG R NH2 1 
ATOM   6698 N N   . SER D 4 319 ? 130.388 144.346 168.463 1.00 114.63 ? 183 SER R N   1 
ATOM   6699 C CA  . SER D 4 319 ? 129.486 145.128 169.304 1.00 114.87 ? 183 SER R CA  1 
ATOM   6700 C C   . SER D 4 319 ? 129.689 144.796 170.777 1.00 115.08 ? 183 SER R C   1 
ATOM   6701 O O   . SER D 4 319 ? 129.723 145.695 171.627 1.00 113.70 ? 183 SER R O   1 
ATOM   6702 C CB  . SER D 4 319 ? 128.036 144.880 168.892 1.00 114.24 ? 183 SER R CB  1 
ATOM   6703 N N   . ARG D 4 320 ? 129.831 143.506 171.094 1.00 116.33 ? 184 ARG R N   1 
ATOM   6704 C CA  . ARG D 4 320 ? 130.102 143.104 172.469 1.00 115.70 ? 184 ARG R CA  1 
ATOM   6705 C C   . ARG D 4 320 ? 131.437 143.658 172.946 1.00 115.30 ? 184 ARG R C   1 
ATOM   6706 O O   . ARG D 4 320 ? 131.554 144.108 174.090 1.00 114.24 ? 184 ARG R O   1 
ATOM   6707 C CB  . ARG D 4 320 ? 130.083 141.580 172.588 1.00 114.82 ? 184 ARG R CB  1 
ATOM   6708 C CG  . ARG D 4 320 ? 128.730 140.948 172.306 1.00 114.73 ? 184 ARG R CG  1 
ATOM   6709 C CD  . ARG D 4 320 ? 127.706 141.341 173.355 1.00 115.39 ? 184 ARG R CD  1 
ATOM   6710 N NE  . ARG D 4 320 ? 128.085 140.891 174.689 1.00 115.36 ? 184 ARG R NE  1 
ATOM   6711 C CZ  . ARG D 4 320 ? 127.874 139.668 175.155 1.00 116.20 ? 184 ARG R CZ  1 
ATOM   6712 N NH1 . ARG D 4 320 ? 127.294 138.736 174.416 1.00 115.20 ? 184 ARG R NH1 1 
ATOM   6713 N NH2 . ARG D 4 320 ? 128.253 139.373 176.395 1.00 115.38 ? 184 ARG R NH2 1 
ATOM   6714 N N   . THR D 4 321 ? 132.455 143.633 172.084 1.00 113.14 ? 185 THR R N   1 
ATOM   6715 C CA  . THR D 4 321 ? 133.756 144.176 172.462 1.00 111.18 ? 185 THR R CA  1 
ATOM   6716 C C   . THR D 4 321 ? 133.674 145.673 172.731 1.00 111.90 ? 185 THR R C   1 
ATOM   6717 O O   . THR D 4 321 ? 134.263 146.169 173.698 1.00 112.87 ? 185 THR R O   1 
ATOM   6718 C CB  . THR D 4 321 ? 134.788 143.887 171.373 1.00 111.91 ? 185 THR R CB  1 
ATOM   6719 O OG1 . THR D 4 321 ? 134.768 142.491 171.052 1.00 112.81 ? 185 THR R OG1 1 
ATOM   6720 C CG2 . THR D 4 321 ? 136.179 144.273 171.845 1.00 110.21 ? 185 THR R CG2 1 
ATOM   6721 N N   . LYS D 4 322 ? 132.955 146.412 171.882 1.00 114.26 ? 186 LYS R N   1 
ATOM   6722 C CA  . LYS D 4 322 ? 132.823 147.852 172.086 1.00 113.65 ? 186 LYS R CA  1 
ATOM   6723 C C   . LYS D 4 322 ? 132.068 148.160 173.374 1.00 113.96 ? 186 LYS R C   1 
ATOM   6724 O O   . LYS D 4 322 ? 132.467 149.046 174.141 1.00 112.61 ? 186 LYS R O   1 
ATOM   6725 C CB  . LYS D 4 322 ? 132.125 148.490 170.886 1.00 111.74 ? 186 LYS R CB  1 
ATOM   6726 N N   . LYS D 4 323 ? 130.979 147.432 173.632 1.00 117.41 ? 187 LYS R N   1 
ATOM   6727 C CA  . LYS D 4 323 ? 130.239 147.633 174.874 1.00 117.17 ? 187 LYS R CA  1 
ATOM   6728 C C   . LYS D 4 323 ? 131.098 147.290 176.084 1.00 117.43 ? 187 LYS R C   1 
ATOM   6729 O O   . LYS D 4 323 ? 131.051 147.985 177.106 1.00 117.28 ? 187 LYS R O   1 
ATOM   6730 C CB  . LYS D 4 323 ? 128.960 146.797 174.867 1.00 115.92 ? 187 LYS R CB  1 
ATOM   6731 N N   . PHE D 4 324 ? 131.893 146.223 175.985 1.00 114.31 ? 188 PHE R N   1 
ATOM   6732 C CA  . PHE D 4 324 ? 132.764 145.829 177.086 1.00 113.66 ? 188 PHE R CA  1 
ATOM   6733 C C   . PHE D 4 324 ? 133.827 146.890 177.341 1.00 113.59 ? 188 PHE R C   1 
ATOM   6734 O O   . PHE D 4 324 ? 134.128 147.203 178.497 1.00 112.95 ? 188 PHE R O   1 
ATOM   6735 C CB  . PHE D 4 324 ? 133.376 144.455 176.773 1.00 113.37 ? 188 PHE R CB  1 
ATOM   6736 C CG  . PHE D 4 324 ? 134.364 143.947 177.801 1.00 113.15 ? 188 PHE R CG  1 
ATOM   6737 C CD1 . PHE D 4 324 ? 135.580 144.574 178.020 1.00 113.03 ? 188 PHE R CD1 1 
ATOM   6738 C CD2 . PHE D 4 324 ? 134.057 142.826 178.554 1.00 113.05 ? 188 PHE R CD2 1 
ATOM   6739 C CE1 . PHE D 4 324 ? 136.458 144.100 178.960 1.00 114.44 ? 188 PHE R CE1 1 
ATOM   6740 C CE2 . PHE D 4 324 ? 134.939 142.346 179.499 1.00 113.63 ? 188 PHE R CE2 1 
ATOM   6741 C CZ  . PHE D 4 324 ? 136.141 142.984 179.701 1.00 114.04 ? 188 PHE R CZ  1 
ATOM   6742 N N   . ILE D 4 325 ? 134.412 147.447 176.279 1.00 110.11 ? 189 ILE R N   1 
ATOM   6743 C CA  . ILE D 4 325 ? 135.422 148.490 176.446 1.00 111.25 ? 189 ILE R CA  1 
ATOM   6744 C C   . ILE D 4 325 ? 134.806 149.729 177.082 1.00 111.63 ? 189 ILE R C   1 
ATOM   6745 O O   . ILE D 4 325 ? 135.397 150.346 177.978 1.00 111.00 ? 189 ILE R O   1 
ATOM   6746 C CB  . ILE D 4 325 ? 136.089 148.816 175.095 1.00 109.72 ? 189 ILE R CB  1 
ATOM   6747 C CG1 . ILE D 4 325 ? 136.981 147.661 174.631 1.00 108.40 ? 189 ILE R CG1 1 
ATOM   6748 C CG2 . ILE D 4 325 ? 136.899 150.099 175.191 1.00 109.47 ? 189 ILE R CG2 1 
ATOM   6749 C CD1 . ILE D 4 325 ? 137.592 146.850 175.756 1.00 108.44 ? 189 ILE R CD1 1 
ATOM   6750 N N   . SER D 4 326 ? 133.608 150.112 176.632 1.00 111.71 ? 190 SER R N   1 
ATOM   6751 C CA  . SER D 4 326 ? 132.930 151.256 177.232 1.00 111.71 ? 190 SER R CA  1 
ATOM   6752 C C   . SER D 4 326 ? 132.641 151.013 178.709 1.00 112.66 ? 190 SER R C   1 
ATOM   6753 O O   . SER D 4 326 ? 132.846 151.902 179.545 1.00 111.51 ? 190 SER R O   1 
ATOM   6754 C CB  . SER D 4 326 ? 131.638 151.556 176.471 1.00 111.15 ? 190 SER R CB  1 
ATOM   6755 N N   . ALA D 4 327 ? 132.173 149.809 179.048 1.00 112.52 ? 191 ALA R N   1 
ATOM   6756 C CA  . ALA D 4 327 ? 131.889 149.487 180.442 1.00 111.72 ? 191 ALA R CA  1 
ATOM   6757 C C   . ALA D 4 327 ? 133.159 149.489 181.282 1.00 111.74 ? 191 ALA R C   1 
ATOM   6758 O O   . ALA D 4 327 ? 133.148 149.946 182.429 1.00 111.97 ? 191 ALA R O   1 
ATOM   6759 C CB  . ALA D 4 327 ? 131.188 148.132 180.535 1.00 110.09 ? 191 ALA R CB  1 
ATOM   6760 N N   . ILE D 4 328 ? 134.260 148.975 180.731 1.00 108.87 ? 192 ILE R N   1 
ATOM   6761 C CA  . ILE D 4 328 ? 135.526 148.959 181.458 1.00 108.76 ? 192 ILE R CA  1 
ATOM   6762 C C   . ILE D 4 328 ? 136.011 150.378 181.710 1.00 109.98 ? 192 ILE R C   1 
ATOM   6763 O O   . ILE D 4 328 ? 136.484 150.703 182.805 1.00 110.79 ? 192 ILE R O   1 
ATOM   6764 C CB  . ILE D 4 328 ? 136.572 148.131 180.690 1.00 107.57 ? 192 ILE R CB  1 
ATOM   6765 N N   . TRP D 4 329 ? 135.904 151.245 180.701 1.00 106.57 ? 193 TRP R N   1 
ATOM   6766 C CA  . TRP D 4 329 ? 136.312 152.634 180.880 1.00 106.02 ? 193 TRP R CA  1 
ATOM   6767 C C   . TRP D 4 329 ? 135.438 153.338 181.909 1.00 106.76 ? 193 TRP R C   1 
ATOM   6768 O O   . TRP D 4 329 ? 135.934 154.138 182.712 1.00 105.72 ? 193 TRP R O   1 
ATOM   6769 C CB  . TRP D 4 329 ? 136.272 153.370 179.542 1.00 105.41 ? 193 TRP R CB  1 
ATOM   6770 C CG  . TRP D 4 329 ? 137.615 153.493 178.894 1.00 106.23 ? 193 TRP R CG  1 
ATOM   6771 C CD1 . TRP D 4 329 ? 138.072 152.794 177.816 1.00 105.85 ? 193 TRP R CD1 1 
ATOM   6772 C CD2 . TRP D 4 329 ? 138.679 154.369 179.284 1.00 106.38 ? 193 TRP R CD2 1 
ATOM   6773 N NE1 . TRP D 4 329 ? 139.354 153.182 177.510 1.00 106.40 ? 193 TRP R NE1 1 
ATOM   6774 C CE2 . TRP D 4 329 ? 139.749 154.148 178.397 1.00 106.26 ? 193 TRP R CE2 1 
ATOM   6775 C CE3 . TRP D 4 329 ? 138.829 155.321 180.297 1.00 105.62 ? 193 TRP R CE3 1 
ATOM   6776 C CZ2 . TRP D 4 329 ? 140.950 154.841 178.492 1.00 104.91 ? 193 TRP R CZ2 1 
ATOM   6777 C CZ3 . TRP D 4 329 ? 140.023 156.007 180.389 1.00 104.71 ? 193 TRP R CZ3 1 
ATOM   6778 C CH2 . TRP D 4 329 ? 141.067 155.765 179.493 1.00 105.02 ? 193 TRP R CH2 1 
ATOM   6779 N N   . LEU D 4 330 ? 134.132 153.061 181.898 1.00 111.52 ? 194 LEU R N   1 
ATOM   6780 C CA  . LEU D 4 330 ? 133.246 153.657 182.894 1.00 111.46 ? 194 LEU R CA  1 
ATOM   6781 C C   . LEU D 4 330 ? 133.578 153.164 184.298 1.00 111.87 ? 194 LEU R C   1 
ATOM   6782 O O   . LEU D 4 330 ? 133.600 153.951 185.252 1.00 112.39 ? 194 LEU R O   1 
ATOM   6783 C CB  . LEU D 4 330 ? 131.788 153.354 182.549 1.00 110.78 ? 194 LEU R CB  1 
ATOM   6784 N N   . ALA D 4 331 ? 133.842 151.864 184.446 1.00 108.12 ? 195 ALA R N   1 
ATOM   6785 C CA  . ALA D 4 331 ? 134.144 151.297 185.754 1.00 107.49 ? 195 ALA R CA  1 
ATOM   6786 C C   . ALA D 4 331 ? 135.529 151.684 186.250 1.00 106.77 ? 195 ALA R C   1 
ATOM   6787 O O   . ALA D 4 331 ? 135.782 151.611 187.458 1.00 106.35 ? 195 ALA R O   1 
ATOM   6788 C CB  . ALA D 4 331 ? 134.015 149.774 185.711 1.00 106.59 ? 195 ALA R CB  1 
ATOM   6789 N N   . SER D 4 332 ? 136.431 152.081 185.349 1.00 106.08 ? 196 SER R N   1 
ATOM   6790 C CA  . SER D 4 332 ? 137.746 152.541 185.780 1.00 106.83 ? 196 SER R CA  1 
ATOM   6791 C C   . SER D 4 332 ? 137.629 153.768 186.674 1.00 108.83 ? 196 SER R C   1 
ATOM   6792 O O   . SER D 4 332 ? 138.321 153.872 187.694 1.00 108.87 ? 196 SER R O   1 
ATOM   6793 C CB  . SER D 4 332 ? 138.620 152.841 184.563 1.00 105.17 ? 196 SER R CB  1 
ATOM   6794 N N   . ALA D 4 333 ? 136.757 154.710 186.309 1.00 106.56 ? 197 ALA R N   1 
ATOM   6795 C CA  . ALA D 4 333 ? 136.495 155.846 187.183 1.00 105.33 ? 197 ALA R CA  1 
ATOM   6796 C C   . ALA D 4 333 ? 135.710 155.431 188.419 1.00 105.47 ? 197 ALA R C   1 
ATOM   6797 O O   . ALA D 4 333 ? 135.875 156.030 189.487 1.00 106.81 ? 197 ALA R O   1 
ATOM   6798 C CB  . ALA D 4 333 ? 135.746 156.936 186.418 1.00 105.33 ? 197 ALA R CB  1 
ATOM   6799 N N   . LEU D 4 334 ? 134.853 154.414 188.294 1.00 103.03 ? 198 LEU R N   1 
ATOM   6800 C CA  . LEU D 4 334 ? 134.075 153.948 189.438 1.00 103.53 ? 198 LEU R CA  1 
ATOM   6801 C C   . LEU D 4 334 ? 134.977 153.378 190.525 1.00 103.68 ? 198 LEU R C   1 
ATOM   6802 O O   . LEU D 4 334 ? 134.740 153.599 191.718 1.00 102.90 ? 198 LEU R O   1 
ATOM   6803 C CB  . LEU D 4 334 ? 133.054 152.904 188.988 1.00 102.90 ? 198 LEU R CB  1 
ATOM   6804 N N   . LEU D 4 335 ? 136.013 152.635 190.134 1.00 104.81 ? 199 LEU R N   1 
ATOM   6805 C CA  . LEU D 4 335 ? 136.953 152.088 191.103 1.00 104.25 ? 199 LEU R CA  1 
ATOM   6806 C C   . LEU D 4 335 ? 137.868 153.149 191.700 1.00 105.08 ? 199 LEU R C   1 
ATOM   6807 O O   . LEU D 4 335 ? 138.551 152.867 192.690 1.00 105.52 ? 199 LEU R O   1 
ATOM   6808 C CB  . LEU D 4 335 ? 137.787 150.983 190.454 1.00 103.28 ? 199 LEU R CB  1 
ATOM   6809 C CG  . LEU D 4 335 ? 137.071 149.650 190.225 1.00 103.01 ? 199 LEU R CG  1 
ATOM   6810 C CD1 . LEU D 4 335 ? 137.882 148.752 189.308 1.00 103.53 ? 199 LEU R CD1 1 
ATOM   6811 C CD2 . LEU D 4 335 ? 136.800 148.955 191.549 1.00 103.23 ? 199 LEU R CD2 1 
ATOM   6812 N N   . ALA D 4 336 ? 137.901 154.351 191.128 1.00 105.29 ? 200 ALA R N   1 
ATOM   6813 C CA  . ALA D 4 336 ? 138.699 155.451 191.651 1.00 105.37 ? 200 ALA R CA  1 
ATOM   6814 C C   . ALA D 4 336 ? 137.859 156.472 192.407 1.00 105.76 ? 200 ALA R C   1 
ATOM   6815 O O   . ALA D 4 336 ? 138.335 157.583 192.664 1.00 105.86 ? 200 ALA R O   1 
ATOM   6816 C CB  . ALA D 4 336 ? 139.463 156.135 190.516 1.00 105.50 ? 200 ALA R CB  1 
ATOM   6817 N N   . VAL D 4 337 ? 136.619 156.124 192.756 1.00 108.91 ? 201 VAL R N   1 
ATOM   6818 C CA  . VAL D 4 337 ? 135.757 157.060 193.480 1.00 108.24 ? 201 VAL R CA  1 
ATOM   6819 C C   . VAL D 4 337 ? 136.347 157.480 194.823 1.00 108.69 ? 201 VAL R C   1 
ATOM   6820 O O   . VAL D 4 337 ? 136.338 158.685 195.124 1.00 108.50 ? 201 VAL R O   1 
ATOM   6821 C CB  . VAL D 4 337 ? 134.341 156.475 193.618 1.00 108.81 ? 201 VAL R CB  1 
ATOM   6822 N N   . PRO D 4 338 ? 136.853 156.573 195.672 1.00 110.79 ? 202 PRO R N   1 
ATOM   6823 C CA  . PRO D 4 338 ? 137.383 157.026 196.971 1.00 110.74 ? 202 PRO R CA  1 
ATOM   6824 C C   . PRO D 4 338 ? 138.513 158.035 196.856 1.00 111.39 ? 202 PRO R C   1 
ATOM   6825 O O   . PRO D 4 338 ? 138.662 158.880 197.747 1.00 110.78 ? 202 PRO R O   1 
ATOM   6826 C CB  . PRO D 4 338 ? 137.855 155.723 197.635 1.00 109.96 ? 202 PRO R CB  1 
ATOM   6827 C CG  . PRO D 4 338 ? 137.974 154.738 196.528 1.00 109.52 ? 202 PRO R CG  1 
ATOM   6828 C CD  . PRO D 4 338 ? 136.894 155.104 195.569 1.00 110.35 ? 202 PRO R CD  1 
ATOM   6829 N N   . MET D 4 339 ? 139.318 157.972 195.793 1.00 109.50 ? 203 MET R N   1 
ATOM   6830 C CA  . MET D 4 339 ? 140.391 158.946 195.626 1.00 107.81 ? 203 MET R CA  1 
ATOM   6831 C C   . MET D 4 339 ? 139.844 160.361 195.485 1.00 108.42 ? 203 MET R C   1 
ATOM   6832 O O   . MET D 4 339 ? 140.525 161.328 195.846 1.00 107.59 ? 203 MET R O   1 
ATOM   6833 C CB  . MET D 4 339 ? 141.251 158.582 194.415 1.00 106.75 ? 203 MET R CB  1 
ATOM   6834 C CG  . MET D 4 339 ? 142.533 157.817 194.736 1.00 106.71 ? 203 MET R CG  1 
ATOM   6835 S SD  . MET D 4 339 ? 142.304 156.374 195.800 1.00 108.74 ? 203 MET R SD  1 
ATOM   6836 C CE  . MET D 4 339 ? 142.755 157.022 197.410 1.00 107.64 ? 203 MET R CE  1 
ATOM   6837 N N   . LEU D 4 340 ? 138.623 160.504 194.962 1.00 110.19 ? 204 LEU R N   1 
ATOM   6838 C CA  . LEU D 4 340 ? 138.004 161.822 194.874 1.00 109.14 ? 204 LEU R CA  1 
ATOM   6839 C C   . LEU D 4 340 ? 137.699 162.381 196.258 1.00 110.45 ? 204 LEU R C   1 
ATOM   6840 O O   . LEU D 4 340 ? 137.767 163.598 196.471 1.00 109.74 ? 204 LEU R O   1 
ATOM   6841 C CB  . LEU D 4 340 ? 136.731 161.750 194.031 1.00 107.61 ? 204 LEU R CB  1 
ATOM   6842 N N   . PHE D 4 341 ? 137.362 161.511 197.210 1.00 115.20 ? 205 PHE R N   1 
ATOM   6843 C CA  . PHE D 4 341 ? 137.062 161.945 198.569 1.00 114.41 ? 205 PHE R CA  1 
ATOM   6844 C C   . PHE D 4 341 ? 138.273 161.858 199.489 1.00 114.73 ? 205 PHE R C   1 
ATOM   6845 O O   . PHE D 4 341 ? 138.457 162.724 200.351 1.00 115.61 ? 205 PHE R O   1 
ATOM   6846 C CB  . PHE D 4 341 ? 135.915 161.112 199.149 1.00 114.32 ? 205 PHE R CB  1 
ATOM   6847 C CG  . PHE D 4 341 ? 134.713 161.025 198.254 1.00 114.56 ? 205 PHE R CG  1 
ATOM   6848 C CD1 . PHE D 4 341 ? 134.218 162.155 197.624 1.00 114.20 ? 205 PHE R CD1 1 
ATOM   6849 C CD2 . PHE D 4 341 ? 134.073 159.815 198.049 1.00 113.81 ? 205 PHE R CD2 1 
ATOM   6850 C CE1 . PHE D 4 341 ? 133.112 162.078 196.801 1.00 113.89 ? 205 PHE R CE1 1 
ATOM   6851 C CE2 . PHE D 4 341 ? 132.965 159.732 197.227 1.00 113.82 ? 205 PHE R CE2 1 
ATOM   6852 C CZ  . PHE D 4 341 ? 132.484 160.865 196.602 1.00 113.66 ? 205 PHE R CZ  1 
ATOM   6853 N N   . THR D 4 342 ? 139.103 160.823 199.327 1.00 112.94 ? 206 THR R N   1 
ATOM   6854 C CA  . THR D 4 342 ? 140.265 160.665 200.197 1.00 114.06 ? 206 THR R CA  1 
ATOM   6855 C C   . THR D 4 342 ? 141.263 161.800 200.007 1.00 114.14 ? 206 THR R C   1 
ATOM   6856 O O   . THR D 4 342 ? 141.831 162.303 200.983 1.00 114.10 ? 206 THR R O   1 
ATOM   6857 C CB  . THR D 4 342 ? 140.940 159.318 199.939 1.00 113.97 ? 206 THR R CB  1 
ATOM   6858 O OG1 . THR D 4 342 ? 139.946 158.337 199.617 1.00 113.52 ? 206 THR R OG1 1 
ATOM   6859 C CG2 . THR D 4 342 ? 141.712 158.866 201.169 1.00 113.33 ? 206 THR R CG2 1 
ATOM   6860 N N   . MET D 4 343 ? 141.489 162.217 198.765 1.00 112.71 ? 207 MET R N   1 
ATOM   6861 C CA  . MET D 4 343 ? 142.470 163.255 198.495 1.00 113.56 ? 207 MET R CA  1 
ATOM   6862 C C   . MET D 4 343 ? 141.950 164.622 198.932 1.00 115.24 ? 207 MET R C   1 
ATOM   6863 O O   . MET D 4 343 ? 140.754 164.826 199.158 1.00 114.82 ? 207 MET R O   1 
ATOM   6864 C CB  . MET D 4 343 ? 142.832 163.279 197.011 1.00 112.37 ? 207 MET R CB  1 
ATOM   6865 N N   . GLY D 4 344 ? 142.877 165.565 199.048 1.00 117.94 ? 208 GLY R N   1 
ATOM   6866 C CA  . GLY D 4 344 ? 142.537 166.908 199.468 1.00 116.35 ? 208 GLY R CA  1 
ATOM   6867 C C   . GLY D 4 344 ? 143.795 167.726 199.675 1.00 116.25 ? 208 GLY R C   1 
ATOM   6868 O O   . GLY D 4 344 ? 144.894 167.316 199.297 1.00 117.47 ? 208 GLY R O   1 
ATOM   6869 N N   . GLU D 4 345 ? 143.610 168.894 200.282 1.00 111.42 ? 209 GLU R N   1 
ATOM   6870 C CA  . GLU D 4 345 ? 144.706 169.802 200.592 1.00 110.88 ? 209 GLU R CA  1 
ATOM   6871 C C   . GLU D 4 345 ? 144.837 169.939 202.102 1.00 111.06 ? 209 GLU R C   1 
ATOM   6872 O O   . GLU D 4 345 ? 143.844 170.180 202.796 1.00 111.50 ? 209 GLU R O   1 
ATOM   6873 C CB  . GLU D 4 345 ? 144.483 171.173 199.950 1.00 109.82 ? 209 GLU R CB  1 
ATOM   6874 N N   . GLN D 4 346 ? 146.059 169.782 202.604 1.00 113.52 ? 210 GLN R N   1 
ATOM   6875 C CA  . GLN D 4 346 ? 146.335 169.901 204.028 1.00 114.30 ? 210 GLN R CA  1 
ATOM   6876 C C   . GLN D 4 346 ? 147.661 170.619 204.226 1.00 114.97 ? 210 GLN R C   1 
ATOM   6877 O O   . GLN D 4 346 ? 148.625 170.372 203.495 1.00 114.56 ? 210 GLN R O   1 
ATOM   6878 C CB  . GLN D 4 346 ? 146.374 168.526 204.708 1.00 113.03 ? 210 GLN R CB  1 
ATOM   6879 N N   . ASN D 4 347 ? 147.700 171.515 205.214 1.00 116.56 ? 211 ASN R N   1 
ATOM   6880 C CA  . ASN D 4 347 ? 148.933 172.239 205.506 1.00 116.60 ? 211 ASN R CA  1 
ATOM   6881 C C   . ASN D 4 347 ? 150.003 171.309 206.063 1.00 116.80 ? 211 ASN R C   1 
ATOM   6882 O O   . ASN D 4 347 ? 151.185 171.445 205.728 1.00 115.91 ? 211 ASN R O   1 
ATOM   6883 C CB  . ASN D 4 347 ? 148.652 173.382 206.480 1.00 116.08 ? 211 ASN R CB  1 
ATOM   6884 N N   . ARG D 4 348 ? 149.604 170.360 206.914 1.00 116.55 ? 212 ARG R N   1 
ATOM   6885 C CA  . ARG D 4 348 ? 150.525 169.402 207.531 1.00 116.35 ? 212 ARG R CA  1 
ATOM   6886 C C   . ARG D 4 348 ? 151.659 170.113 208.267 1.00 117.20 ? 212 ARG R C   1 
ATOM   6887 O O   . ARG D 4 348 ? 152.819 169.701 208.206 1.00 116.83 ? 212 ARG R O   1 
ATOM   6888 C CB  . ARG D 4 348 ? 151.079 168.419 206.495 1.00 114.74 ? 212 ARG R CB  1 
ATOM   6889 N N   . SER D 4 349 ? 151.319 171.189 208.969 1.00 116.60 ? 213 SER R N   1 
ATOM   6890 C CA  . SER D 4 349 ? 152.296 171.969 209.717 1.00 115.37 ? 213 SER R CA  1 
ATOM   6891 C C   . SER D 4 349 ? 151.593 172.596 210.916 1.00 115.82 ? 213 SER R C   1 
ATOM   6892 O O   . SER D 4 349 ? 150.431 172.295 211.204 1.00 115.28 ? 213 SER R O   1 
ATOM   6893 C CB  . SER D 4 349 ? 152.955 173.020 208.814 1.00 114.00 ? 213 SER R CB  1 
ATOM   6894 N N   . ALA D 4 350 ? 152.312 173.469 211.626 1.00 118.95 ? 214 ALA R N   1 
ATOM   6895 C CA  . ALA D 4 350 ? 151.719 174.162 212.765 1.00 118.86 ? 214 ALA R CA  1 
ATOM   6896 C C   . ALA D 4 350 ? 150.592 175.087 212.324 1.00 118.03 ? 214 ALA R C   1 
ATOM   6897 O O   . ALA D 4 350 ? 149.550 175.168 212.985 1.00 117.24 ? 214 ALA R O   1 
ATOM   6898 C CB  . ALA D 4 350 ? 152.793 174.944 213.521 1.00 117.85 ? 214 ALA R CB  1 
ATOM   6899 N N   . ASP D 4 351 ? 150.782 175.794 211.213 1.00 117.47 ? 215 ASP R N   1 
ATOM   6900 C CA  . ASP D 4 351 ? 149.774 176.714 210.707 1.00 116.53 ? 215 ASP R CA  1 
ATOM   6901 C C   . ASP D 4 351 ? 149.900 176.808 209.195 1.00 117.16 ? 215 ASP R C   1 
ATOM   6902 O O   . ASP D 4 351 ? 150.943 176.492 208.617 1.00 116.96 ? 215 ASP R O   1 
ATOM   6903 C CB  . ASP D 4 351 ? 149.907 178.102 211.346 1.00 116.15 ? 215 ASP R CB  1 
ATOM   6904 N N   . GLY D 4 352 ? 148.819 177.252 208.559 1.00 119.20 ? 216 GLY R N   1 
ATOM   6905 C CA  . GLY D 4 352 ? 148.794 177.391 207.116 1.00 119.26 ? 216 GLY R CA  1 
ATOM   6906 C C   . GLY D 4 352 ? 149.150 178.786 206.646 1.00 119.54 ? 216 GLY R C   1 
ATOM   6907 O O   . GLY D 4 352 ? 148.903 179.142 205.490 1.00 119.41 ? 216 GLY R O   1 
ATOM   6908 N N   . GLN D 4 353 ? 149.737 179.585 207.535 1.00 120.46 ? 217 GLN R N   1 
ATOM   6909 C CA  . GLN D 4 353 ? 150.103 180.958 207.216 1.00 120.00 ? 217 GLN R CA  1 
ATOM   6910 C C   . GLN D 4 353 ? 151.460 181.071 206.535 1.00 120.91 ? 217 GLN R C   1 
ATOM   6911 O O   . GLN D 4 353 ? 151.870 182.185 206.192 1.00 120.41 ? 217 GLN R O   1 
ATOM   6912 C CB  . GLN D 4 353 ? 150.095 181.813 208.486 1.00 118.74 ? 217 GLN R CB  1 
ATOM   6913 N N   . HIS D 4 354 ? 152.162 179.960 206.329 1.00 121.48 ? 218 HIS R N   1 
ATOM   6914 C CA  . HIS D 4 354 ? 153.478 179.972 205.712 1.00 121.06 ? 218 HIS R CA  1 
ATOM   6915 C C   . HIS D 4 354 ? 153.512 178.981 204.558 1.00 121.13 ? 218 HIS R C   1 
ATOM   6916 O O   . HIS D 4 354 ? 152.732 178.027 204.504 1.00 120.32 ? 218 HIS R O   1 
ATOM   6917 C CB  . HIS D 4 354 ? 154.579 179.635 206.728 1.00 119.85 ? 218 HIS R CB  1 
ATOM   6918 N N   . ALA D 4 355 ? 154.435 179.223 203.628 1.00 119.48 ? 219 ALA R N   1 
ATOM   6919 C CA  . ALA D 4 355 ? 154.637 178.355 202.476 1.00 119.28 ? 219 ALA R CA  1 
ATOM   6920 C C   . ALA D 4 355 ? 155.509 177.146 202.792 1.00 120.15 ? 219 ALA R C   1 
ATOM   6921 O O   . ALA D 4 355 ? 156.035 176.519 201.864 1.00 119.74 ? 219 ALA R O   1 
ATOM   6922 C CB  . ALA D 4 355 ? 155.246 179.149 201.318 1.00 118.08 ? 219 ALA R CB  1 
ATOM   6923 N N   . GLY D 4 356 ? 155.679 176.814 204.074 1.00 119.33 ? 220 GLY R N   1 
ATOM   6924 C CA  . GLY D 4 356 ? 156.497 175.666 204.430 1.00 118.95 ? 220 GLY R CA  1 
ATOM   6925 C C   . GLY D 4 356 ? 155.944 174.361 203.890 1.00 119.62 ? 220 GLY R C   1 
ATOM   6926 O O   . GLY D 4 356 ? 156.692 173.525 203.379 1.00 118.95 ? 220 GLY R O   1 
ATOM   6927 N N   . GLY D 4 357 ? 154.633 174.166 203.998 1.00 120.67 ? 221 GLY R N   1 
ATOM   6928 C CA  . GLY D 4 357 ? 154.018 172.979 203.439 1.00 119.84 ? 221 GLY R CA  1 
ATOM   6929 C C   . GLY D 4 357 ? 152.570 173.152 203.033 1.00 120.45 ? 221 GLY R C   1 
ATOM   6930 O O   . GLY D 4 357 ? 151.728 173.559 203.840 1.00 119.81 ? 221 GLY R O   1 
ATOM   6931 N N   . LEU D 4 358 ? 152.272 172.843 201.769 1.00 122.53 ? 222 LEU R N   1 
ATOM   6932 C CA  . LEU D 4 358 ? 150.891 172.782 201.291 1.00 121.87 ? 222 LEU R CA  1 
ATOM   6933 C C   . LEU D 4 358 ? 150.898 171.880 200.057 1.00 121.95 ? 222 LEU R C   1 
ATOM   6934 O O   . LEU D 4 358 ? 151.251 172.333 198.965 1.00 121.35 ? 222 LEU R O   1 
ATOM   6935 C CB  . LEU D 4 358 ? 150.350 174.166 200.973 1.00 120.55 ? 222 LEU R CB  1 
ATOM   6936 N N   . VAL D 4 359 ? 150.514 170.619 200.241 1.00 120.99 ? 223 VAL R N   1 
ATOM   6937 C CA  . VAL D 4 359 ? 150.583 169.641 199.161 1.00 120.58 ? 223 VAL R CA  1 
ATOM   6938 C C   . VAL D 4 359 ? 149.451 168.631 199.293 1.00 120.66 ? 223 VAL R C   1 
ATOM   6939 O O   . VAL D 4 359 ? 148.679 168.667 200.258 1.00 120.96 ? 223 VAL R O   1 
ATOM   6940 C CB  . VAL D 4 359 ? 151.949 168.932 199.144 1.00 119.98 ? 223 VAL R CB  1 
ATOM   6941 N N   . CYS D 4 360 ? 149.346 167.728 198.321 1.00 116.41 ? 224 CYS R N   1 
ATOM   6942 C CA  . CYS D 4 360 ? 148.335 166.682 198.370 1.00 115.41 ? 224 CYS R CA  1 
ATOM   6943 C C   . CYS D 4 360 ? 148.594 165.744 199.540 1.00 116.02 ? 224 CYS R C   1 
ATOM   6944 O O   . CYS D 4 360 ? 149.734 165.352 199.803 1.00 116.61 ? 224 CYS R O   1 
ATOM   6945 C CB  . CYS D 4 360 ? 148.324 165.890 197.064 1.00 115.22 ? 224 CYS R CB  1 
ATOM   6946 S SG  . CYS D 4 360 ? 147.747 166.817 195.635 1.00 117.72 ? 224 CYS R SG  1 
ATOM   6947 N N   . THR D 4 361 ? 147.520 165.380 200.244 1.00 118.60 ? 225 THR R N   1 
ATOM   6948 C CA  . THR D 4 361 ? 147.627 164.483 201.384 1.00 118.99 ? 225 THR R CA  1 
ATOM   6949 C C   . THR D 4 361 ? 146.252 163.925 201.696 1.00 119.14 ? 225 THR R C   1 
ATOM   6950 O O   . THR D 4 361 ? 145.279 164.692 201.711 1.00 119.29 ? 225 THR R O   1 
ATOM   6951 C CB  . THR D 4 361 ? 148.192 165.200 202.616 1.00 119.11 ? 225 THR R CB  1 
ATOM   6952 N N   . PRO D 4 362 ? 146.125 162.625 201.944 1.00 117.81 ? 226 PRO R N   1 
ATOM   6953 C CA  . PRO D 4 362 ? 144.816 162.071 202.311 1.00 118.32 ? 226 PRO R CA  1 
ATOM   6954 C C   . PRO D 4 362 ? 144.388 162.495 203.707 1.00 119.68 ? 226 PRO R C   1 
ATOM   6955 O O   . PRO D 4 362 ? 144.979 162.071 204.705 1.00 118.52 ? 226 PRO R O   1 
ATOM   6956 C CB  . PRO D 4 362 ? 145.039 160.556 202.222 1.00 116.33 ? 226 PRO R CB  1 
ATOM   6957 C CG  . PRO D 4 362 ? 146.498 160.379 202.455 1.00 116.76 ? 226 PRO R CG  1 
ATOM   6958 C CD  . PRO D 4 362 ? 147.171 161.592 201.877 1.00 117.14 ? 226 PRO R CD  1 
ATOM   6959 N N   . THR D 4 363 ? 143.361 163.339 203.785 1.00 117.81 ? 227 THR R N   1 
ATOM   6960 C CA  . THR D 4 363 ? 142.847 163.809 205.064 1.00 116.24 ? 227 THR R CA  1 
ATOM   6961 C C   . THR D 4 363 ? 141.848 162.845 205.689 1.00 116.27 ? 227 THR R C   1 
ATOM   6962 O O   . THR D 4 363 ? 141.380 163.100 206.804 1.00 116.34 ? 227 THR R O   1 
ATOM   6963 C CB  . THR D 4 363 ? 142.195 165.185 204.897 1.00 115.14 ? 227 THR R CB  1 
ATOM   6964 N N   . ILE D 4 364 ? 141.515 161.752 205.005 1.00 113.89 ? 228 ILE R N   1 
ATOM   6965 C CA  . ILE D 4 364 ? 140.566 160.769 205.515 1.00 114.11 ? 228 ILE R CA  1 
ATOM   6966 C C   . ILE D 4 364 ? 141.197 160.003 206.669 1.00 113.55 ? 228 ILE R C   1 
ATOM   6967 O O   . ILE D 4 364 ? 142.405 160.105 206.912 1.00 111.73 ? 228 ILE R O   1 
ATOM   6968 C CB  . ILE D 4 364 ? 140.105 159.811 204.402 1.00 112.44 ? 228 ILE R CB  1 
ATOM   6969 N N   . HIS D 4 365 ? 140.383 159.236 207.389 1.00 114.92 ? 229 HIS R N   1 
ATOM   6970 C CA  . HIS D 4 365 ? 140.871 158.471 208.526 1.00 114.77 ? 229 HIS R CA  1 
ATOM   6971 C C   . HIS D 4 365 ? 141.842 157.384 208.071 1.00 115.84 ? 229 HIS R C   1 
ATOM   6972 O O   . HIS D 4 365 ? 141.884 156.996 206.899 1.00 116.30 ? 229 HIS R O   1 
ATOM   6973 C CB  . HIS D 4 365 ? 139.704 157.847 209.291 1.00 113.93 ? 229 HIS R CB  1 
ATOM   6974 N N   . THR D 4 366 ? 142.636 156.894 209.027 1.00 112.52 ? 230 THR R N   1 
ATOM   6975 C CA  . THR D 4 366 ? 143.645 155.887 208.713 1.00 111.88 ? 230 THR R CA  1 
ATOM   6976 C C   . THR D 4 366 ? 143.008 154.598 208.210 1.00 111.04 ? 230 THR R C   1 
ATOM   6977 O O   . THR D 4 366 ? 143.522 153.966 207.279 1.00 111.01 ? 230 THR R O   1 
ATOM   6978 C CB  . THR D 4 366 ? 144.512 155.608 209.941 1.00 110.58 ? 230 THR R CB  1 
ATOM   6979 N N   . ALA D 4 367 ? 141.894 154.184 208.819 1.00 108.40 ? 231 ALA R N   1 
ATOM   6980 C CA  . ALA D 4 367 ? 141.215 152.973 208.371 1.00 109.16 ? 231 ALA R CA  1 
ATOM   6981 C C   . ALA D 4 367 ? 140.713 153.119 206.940 1.00 109.42 ? 231 ALA R C   1 
ATOM   6982 O O   . ALA D 4 367 ? 140.841 152.192 206.131 1.00 108.08 ? 231 ALA R O   1 
ATOM   6983 C CB  . ALA D 4 367 ? 140.060 152.636 209.314 1.00 108.84 ? 231 ALA R CB  1 
ATOM   6984 N N   . THR D 4 368 ? 140.138 154.278 206.609 1.00 110.89 ? 232 THR R N   1 
ATOM   6985 C CA  . THR D 4 368 ? 139.663 154.507 205.248 1.00 111.65 ? 232 THR R CA  1 
ATOM   6986 C C   . THR D 4 368 ? 140.818 154.511 204.253 1.00 111.77 ? 232 THR R C   1 
ATOM   6987 O O   . THR D 4 368 ? 140.700 153.961 203.151 1.00 111.34 ? 232 THR R O   1 
ATOM   6988 C CB  . THR D 4 368 ? 138.889 155.823 205.174 1.00 111.10 ? 232 THR R CB  1 
ATOM   6989 O OG1 . THR D 4 368 ? 139.652 156.863 205.796 1.00 110.68 ? 232 THR R OG1 1 
ATOM   6990 C CG2 . THR D 4 368 ? 137.549 155.691 205.882 1.00 110.64 ? 232 THR R CG2 1 
ATOM   6991 N N   . VAL D 4 369 ? 141.942 155.129 204.623 1.00 109.35 ? 233 VAL R N   1 
ATOM   6992 C CA  . VAL D 4 369 ? 143.107 155.147 203.742 1.00 109.12 ? 233 VAL R CA  1 
ATOM   6993 C C   . VAL D 4 369 ? 143.625 153.733 203.515 1.00 109.57 ? 233 VAL R C   1 
ATOM   6994 O O   . VAL D 4 369 ? 143.971 153.354 202.389 1.00 108.51 ? 233 VAL R O   1 
ATOM   6995 C CB  . VAL D 4 369 ? 144.201 156.064 204.321 1.00 106.67 ? 233 VAL R CB  1 
ATOM   6996 N N   . LYS D 4 370 ? 143.692 152.932 204.582 1.00 109.95 ? 234 LYS R N   1 
ATOM   6997 C CA  . LYS D 4 370 ? 144.146 151.552 204.446 1.00 108.91 ? 234 LYS R CA  1 
ATOM   6998 C C   . LYS D 4 370 ? 143.200 150.745 203.567 1.00 108.80 ? 234 LYS R C   1 
ATOM   6999 O O   . LYS D 4 370 ? 143.646 149.944 202.737 1.00 108.56 ? 234 LYS R O   1 
ATOM   7000 C CB  . LYS D 4 370 ? 144.280 150.906 205.825 1.00 108.15 ? 234 LYS R CB  1 
ATOM   7001 N N   . VAL D 4 371 ? 141.891 150.942 203.734 1.00 108.75 ? 235 VAL R N   1 
ATOM   7002 C CA  . VAL D 4 371 ? 140.918 150.231 202.909 1.00 109.52 ? 235 VAL R CA  1 
ATOM   7003 C C   . VAL D 4 371 ? 141.083 150.612 201.444 1.00 109.36 ? 235 VAL R C   1 
ATOM   7004 O O   . VAL D 4 371 ? 141.069 149.749 200.557 1.00 110.02 ? 235 VAL R O   1 
ATOM   7005 C CB  . VAL D 4 371 ? 139.488 150.508 203.411 1.00 109.63 ? 235 VAL R CB  1 
ATOM   7006 C CG1 . VAL D 4 371 ? 138.465 150.163 202.340 1.00 108.14 ? 235 VAL R CG1 1 
ATOM   7007 C CG2 . VAL D 4 371 ? 139.214 149.726 204.686 1.00 108.86 ? 235 VAL R CG2 1 
ATOM   7008 N N   . VAL D 4 372 ? 141.250 151.908 201.167 1.00 107.10 ? 236 VAL R N   1 
ATOM   7009 C CA  . VAL D 4 372 ? 141.414 152.364 199.789 1.00 107.94 ? 236 VAL R CA  1 
ATOM   7010 C C   . VAL D 4 372 ? 142.688 151.791 199.181 1.00 108.30 ? 236 VAL R C   1 
ATOM   7011 O O   . VAL D 4 372 ? 142.693 151.334 198.031 1.00 107.86 ? 236 VAL R O   1 
ATOM   7012 C CB  . VAL D 4 372 ? 141.401 153.902 199.728 1.00 106.84 ? 236 VAL R CB  1 
ATOM   7013 N N   . ILE D 4 373 ? 143.786 151.804 199.941 1.00 106.70 ? 237 ILE R N   1 
ATOM   7014 C CA  . ILE D 4 373 ? 145.052 151.286 199.429 1.00 105.91 ? 237 ILE R CA  1 
ATOM   7015 C C   . ILE D 4 373 ? 144.950 149.790 199.162 1.00 106.63 ? 237 ILE R C   1 
ATOM   7016 O O   . ILE D 4 373 ? 145.448 149.292 198.145 1.00 106.08 ? 237 ILE R O   1 
ATOM   7017 C CB  . ILE D 4 373 ? 146.198 151.612 200.404 1.00 105.16 ? 237 ILE R CB  1 
ATOM   7018 N N   . GLN D 4 374 ? 144.317 149.047 200.073 1.00 107.44 ? 238 GLN R N   1 
ATOM   7019 C CA  . GLN D 4 374 ? 144.160 147.610 199.875 1.00 107.35 ? 238 GLN R CA  1 
ATOM   7020 C C   . GLN D 4 374 ? 143.292 147.313 198.661 1.00 107.45 ? 238 GLN R C   1 
ATOM   7021 O O   . GLN D 4 374 ? 143.586 146.394 197.889 1.00 107.77 ? 238 GLN R O   1 
ATOM   7022 C CB  . GLN D 4 374 ? 143.568 146.967 201.130 1.00 106.83 ? 238 GLN R CB  1 
ATOM   7023 N N   . VAL D 4 375 ? 142.215 148.081 198.474 1.00 104.30 ? 239 VAL R N   1 
ATOM   7024 C CA  . VAL D 4 375 ? 141.363 147.891 197.305 1.00 104.27 ? 239 VAL R CA  1 
ATOM   7025 C C   . VAL D 4 375 ? 142.146 148.169 196.029 1.00 105.76 ? 239 VAL R C   1 
ATOM   7026 O O   . VAL D 4 375 ? 142.039 147.429 195.044 1.00 106.12 ? 239 VAL R O   1 
ATOM   7027 C CB  . VAL D 4 375 ? 140.110 148.780 197.406 1.00 102.67 ? 239 VAL R CB  1 
ATOM   7028 N N   . ASN D 4 376 ? 142.946 149.239 196.027 1.00 103.19 ? 240 ASN R N   1 
ATOM   7029 C CA  . ASN D 4 376 ? 143.757 149.562 194.857 1.00 104.09 ? 240 ASN R CA  1 
ATOM   7030 C C   . ASN D 4 376 ? 144.750 148.447 194.551 1.00 103.85 ? 240 ASN R C   1 
ATOM   7031 O O   . ASN D 4 376 ? 144.903 148.033 193.395 1.00 102.35 ? 240 ASN R O   1 
ATOM   7032 C CB  . ASN D 4 376 ? 144.485 150.889 195.078 1.00 102.23 ? 240 ASN R CB  1 
ATOM   7033 C CG  . ASN D 4 376 ? 145.136 151.416 193.814 1.00 101.32 ? 240 ASN R CG  1 
ATOM   7034 O OD1 . ASN D 4 376 ? 144.785 151.013 192.706 1.00 102.94 ? 240 ASN R OD1 1 
ATOM   7035 N ND2 . ASN D 4 376 ? 146.092 152.323 193.976 1.00 100.14 ? 240 ASN R ND2 1 
ATOM   7036 N N   . THR D 4 377 ? 145.429 147.943 195.583 1.00 104.28 ? 241 THR R N   1 
ATOM   7037 C CA  . THR D 4 377 ? 146.397 146.872 195.376 1.00 103.95 ? 241 THR R CA  1 
ATOM   7038 C C   . THR D 4 377 ? 145.722 145.615 194.843 1.00 103.94 ? 241 THR R C   1 
ATOM   7039 O O   . THR D 4 377 ? 146.218 144.990 193.901 1.00 103.86 ? 241 THR R O   1 
ATOM   7040 C CB  . THR D 4 377 ? 147.135 146.569 196.680 1.00 104.09 ? 241 THR R CB  1 
ATOM   7041 N N   . PHE D 4 378 ? 144.578 145.243 195.421 1.00 104.08 ? 242 PHE R N   1 
ATOM   7042 C CA  . PHE D 4 378 ? 143.879 144.042 194.977 1.00 103.50 ? 242 PHE R CA  1 
ATOM   7043 C C   . PHE D 4 378 ? 143.372 144.186 193.548 1.00 104.23 ? 242 PHE R C   1 
ATOM   7044 O O   . PHE D 4 378 ? 143.423 143.228 192.768 1.00 103.67 ? 242 PHE R O   1 
ATOM   7045 C CB  . PHE D 4 378 ? 142.722 143.729 195.925 1.00 102.74 ? 242 PHE R CB  1 
ATOM   7046 N N   . MET D 4 379 ? 142.881 145.368 193.182 1.00 105.45 ? 243 MET R N   1 
ATOM   7047 C CA  . MET D 4 379 ? 142.258 145.556 191.881 1.00 105.86 ? 243 MET R CA  1 
ATOM   7048 C C   . MET D 4 379 ? 143.236 145.950 190.782 1.00 106.78 ? 243 MET R C   1 
ATOM   7049 O O   . MET D 4 379 ? 142.843 145.968 189.611 1.00 106.10 ? 243 MET R O   1 
ATOM   7050 C CB  . MET D 4 379 ? 141.154 146.615 191.979 1.00 103.53 ? 243 MET R CB  1 
ATOM   7051 N N   . SER D 4 380 ? 144.493 146.265 191.111 1.00 102.07 ? 244 SER R N   1 
ATOM   7052 C CA  . SER D 4 380 ? 145.439 146.668 190.081 1.00 99.41  ? 244 SER R CA  1 
ATOM   7053 C C   . SER D 4 380 ? 146.803 145.990 190.157 1.00 100.90 ? 244 SER R C   1 
ATOM   7054 O O   . SER D 4 380 ? 147.645 146.251 189.291 1.00 101.10 ? 244 SER R O   1 
ATOM   7055 C CB  . SER D 4 380 ? 145.636 148.191 190.114 1.00 98.53  ? 244 SER R CB  1 
ATOM   7056 N N   . PHE D 4 381 ? 147.051 145.133 191.140 1.00 102.77 ? 245 PHE R N   1 
ATOM   7057 C CA  . PHE D 4 381 ? 148.345 144.460 191.224 1.00 102.14 ? 245 PHE R CA  1 
ATOM   7058 C C   . PHE D 4 381 ? 148.228 142.951 191.342 1.00 100.32 ? 245 PHE R C   1 
ATOM   7059 O O   . PHE D 4 381 ? 149.058 142.233 190.783 1.00 97.57  ? 245 PHE R O   1 
ATOM   7060 C CB  . PHE D 4 381 ? 149.151 144.994 192.419 1.00 102.09 ? 245 PHE R CB  1 
ATOM   7061 N N   . ILE D 4 382 ? 147.227 142.453 192.063 1.00 105.76 ? 246 ILE R N   1 
ATOM   7062 C CA  . ILE D 4 382 ? 147.080 141.020 192.285 1.00 105.18 ? 246 ILE R CA  1 
ATOM   7063 C C   . ILE D 4 382 ? 146.168 140.434 191.217 1.00 105.50 ? 246 ILE R C   1 
ATOM   7064 O O   . ILE D 4 382 ? 146.574 139.545 190.461 1.00 106.54 ? 246 ILE R O   1 
ATOM   7065 C CB  . ILE D 4 382 ? 146.539 140.727 193.695 1.00 103.70 ? 246 ILE R CB  1 
ATOM   7066 N N   . PHE D 4 383 ? 144.935 140.932 191.146 1.00 100.52 ? 247 PHE R N   1 
ATOM   7067 C CA  . PHE D 4 383 ? 143.962 140.378 190.206 1.00 100.99 ? 247 PHE R CA  1 
ATOM   7068 C C   . PHE D 4 383 ? 144.405 140.492 188.751 1.00 102.33 ? 247 PHE R C   1 
ATOM   7069 O O   . PHE D 4 383 ? 144.467 139.453 188.068 1.00 102.54 ? 247 PHE R O   1 
ATOM   7070 C CB  . PHE D 4 383 ? 142.602 141.045 190.442 1.00 101.67 ? 247 PHE R CB  1 
ATOM   7071 C CG  . PHE D 4 383 ? 141.517 140.563 189.524 1.00 102.41 ? 247 PHE R CG  1 
ATOM   7072 C CD1 . PHE D 4 383 ? 140.857 139.372 189.776 1.00 102.03 ? 247 PHE R CD1 1 
ATOM   7073 C CD2 . PHE D 4 383 ? 141.147 141.307 188.417 1.00 101.22 ? 247 PHE R CD2 1 
ATOM   7074 C CE1 . PHE D 4 383 ? 139.853 138.929 188.935 1.00 102.05 ? 247 PHE R CE1 1 
ATOM   7075 C CE2 . PHE D 4 383 ? 140.144 140.870 187.572 1.00 101.79 ? 247 PHE R CE2 1 
ATOM   7076 C CZ  . PHE D 4 383 ? 139.497 139.679 187.831 1.00 102.38 ? 247 PHE R CZ  1 
ATOM   7077 N N   . PRO D 4 384 ? 144.755 141.672 188.220 1.00 101.85 ? 248 PRO R N   1 
ATOM   7078 C CA  . PRO D 4 384 ? 145.082 141.726 186.786 1.00 100.64 ? 248 PRO R CA  1 
ATOM   7079 C C   . PRO D 4 384 ? 146.395 141.048 186.444 1.00 102.66 ? 248 PRO R C   1 
ATOM   7080 O O   . PRO D 4 384 ? 146.478 140.365 185.417 1.00 104.12 ? 248 PRO R O   1 
ATOM   7081 C CB  . PRO D 4 384 ? 145.121 143.231 186.495 1.00 99.96  ? 248 PRO R CB  1 
ATOM   7082 C CG  . PRO D 4 384 ? 145.525 143.834 187.774 1.00 102.00 ? 248 PRO R CG  1 
ATOM   7083 C CD  . PRO D 4 384 ? 144.908 142.993 188.857 1.00 101.63 ? 248 PRO R CD  1 
ATOM   7084 N N   . MET D 4 385 ? 147.427 141.215 187.275 1.00 103.48 ? 249 MET R N   1 
ATOM   7085 C CA  . MET D 4 385 ? 148.701 140.557 187.005 1.00 102.04 ? 249 MET R CA  1 
ATOM   7086 C C   . MET D 4 385 ? 148.562 139.043 187.069 1.00 102.15 ? 249 MET R C   1 
ATOM   7087 O O   . MET D 4 385 ? 149.122 138.326 186.232 1.00 101.82 ? 249 MET R O   1 
ATOM   7088 C CB  . MET D 4 385 ? 149.765 141.039 187.988 1.00 100.91 ? 249 MET R CB  1 
ATOM   7089 N N   . VAL D 4 386 ? 147.813 138.537 188.052 1.00 101.92 ? 250 VAL R N   1 
ATOM   7090 C CA  . VAL D 4 386 ? 147.599 137.097 188.162 1.00 101.77 ? 250 VAL R CA  1 
ATOM   7091 C C   . VAL D 4 386 ? 146.824 136.579 186.959 1.00 101.19 ? 250 VAL R C   1 
ATOM   7092 O O   . VAL D 4 386 ? 147.153 135.526 186.397 1.00 101.45 ? 250 VAL R O   1 
ATOM   7093 C CB  . VAL D 4 386 ? 146.884 136.762 189.484 1.00 101.28 ? 250 VAL R CB  1 
ATOM   7094 N N   . VAL D 4 387 ? 145.784 137.308 186.541 1.00 98.10  ? 251 VAL R N   1 
ATOM   7095 C CA  . VAL D 4 387 ? 145.009 136.887 185.377 1.00 99.32  ? 251 VAL R CA  1 
ATOM   7096 C C   . VAL D 4 387 ? 145.895 136.841 184.138 1.00 98.23  ? 251 VAL R C   1 
ATOM   7097 O O   . VAL D 4 387 ? 145.886 135.861 183.381 1.00 96.66  ? 251 VAL R O   1 
ATOM   7098 C CB  . VAL D 4 387 ? 143.800 137.819 185.176 1.00 97.75  ? 251 VAL R CB  1 
ATOM   7099 C CG1 . VAL D 4 387 ? 143.289 137.732 183.749 1.00 96.63  ? 251 VAL R CG1 1 
ATOM   7100 C CG2 . VAL D 4 387 ? 142.698 137.470 186.160 1.00 97.40  ? 251 VAL R CG2 1 
ATOM   7101 N N   . ILE D 4 388 ? 146.687 137.893 183.924 1.00 101.30 ? 252 ILE R N   1 
ATOM   7102 C CA  . ILE D 4 388 ? 147.544 137.954 182.743 1.00 101.12 ? 252 ILE R CA  1 
ATOM   7103 C C   . ILE D 4 388 ? 148.556 136.816 182.764 1.00 103.00 ? 252 ILE R C   1 
ATOM   7104 O O   . ILE D 4 388 ? 148.779 136.143 181.751 1.00 104.88 ? 252 ILE R O   1 
ATOM   7105 C CB  . ILE D 4 388 ? 148.239 139.325 182.652 1.00 99.48  ? 252 ILE R CB  1 
ATOM   7106 N N   . SER D 4 389 ? 149.177 136.579 183.923 1.00 101.81 ? 253 SER R N   1 
ATOM   7107 C CA  . SER D 4 389 ? 150.169 135.515 184.029 1.00 100.89 ? 253 SER R CA  1 
ATOM   7108 C C   . SER D 4 389 ? 149.551 134.159 183.724 1.00 100.23 ? 253 SER R C   1 
ATOM   7109 O O   . SER D 4 389 ? 150.097 133.378 182.935 1.00 101.02 ? 253 SER R O   1 
ATOM   7110 C CB  . SER D 4 389 ? 150.794 135.520 185.424 1.00 100.43 ? 253 SER R CB  1 
ATOM   7111 N N   . VAL D 4 390 ? 148.393 133.871 184.323 1.00 100.69 ? 254 VAL R N   1 
ATOM   7112 C CA  . VAL D 4 390 ? 147.763 132.568 184.131 1.00 102.23 ? 254 VAL R CA  1 
ATOM   7113 C C   . VAL D 4 390 ? 147.390 132.369 182.668 1.00 101.80 ? 254 VAL R C   1 
ATOM   7114 O O   . VAL D 4 390 ? 147.690 131.329 182.066 1.00 100.52 ? 254 VAL R O   1 
ATOM   7115 C CB  . VAL D 4 390 ? 146.539 132.426 185.055 1.00 102.10 ? 254 VAL R CB  1 
ATOM   7116 C CG1 . VAL D 4 390 ? 145.536 131.438 184.476 1.00 99.40  ? 254 VAL R CG1 1 
ATOM   7117 C CG2 . VAL D 4 390 ? 146.978 131.997 186.448 1.00 101.63 ? 254 VAL R CG2 1 
ATOM   7118 N N   . LEU D 4 391 ? 146.753 133.376 182.063 1.00 102.02 ? 255 LEU R N   1 
ATOM   7119 C CA  . LEU D 4 391 ? 146.269 133.211 180.696 1.00 100.34 ? 255 LEU R CA  1 
ATOM   7120 C C   . LEU D 4 391 ? 147.423 133.110 179.706 1.00 98.62  ? 255 LEU R C   1 
ATOM   7121 O O   . LEU D 4 391 ? 147.387 132.282 178.787 1.00 98.43  ? 255 LEU R O   1 
ATOM   7122 C CB  . LEU D 4 391 ? 145.333 134.360 180.325 1.00 101.85 ? 255 LEU R CB  1 
ATOM   7123 C CG  . LEU D 4 391 ? 144.113 134.627 181.217 1.00 100.59 ? 255 LEU R CG  1 
ATOM   7124 C CD1 . LEU D 4 391 ? 142.997 135.259 180.412 1.00 100.20 ? 255 LEU R CD1 1 
ATOM   7125 C CD2 . LEU D 4 391 ? 143.614 133.382 181.946 1.00 100.44 ? 255 LEU R CD2 1 
ATOM   7126 N N   . ASN D 4 392 ? 148.463 133.931 179.880 1.00 98.15  ? 256 ASN R N   1 
ATOM   7127 C CA  . ASN D 4 392 ? 149.607 133.861 178.979 1.00 98.91  ? 256 ASN R CA  1 
ATOM   7128 C C   . ASN D 4 392 ? 150.356 132.544 179.133 1.00 100.40 ? 256 ASN R C   1 
ATOM   7129 O O   . ASN D 4 392 ? 150.823 131.975 178.140 1.00 100.64 ? 256 ASN R O   1 
ATOM   7130 C CB  . ASN D 4 392 ? 150.544 135.041 179.223 1.00 97.73  ? 256 ASN R CB  1 
ATOM   7131 N N   . THR D 4 393 ? 150.491 132.044 180.364 1.00 99.28  ? 257 THR R N   1 
ATOM   7132 C CA  . THR D 4 393 ? 151.157 130.761 180.556 1.00 98.34  ? 257 THR R CA  1 
ATOM   7133 C C   . THR D 4 393 ? 150.369 129.627 179.913 1.00 98.35  ? 257 THR R C   1 
ATOM   7134 O O   . THR D 4 393 ? 150.958 128.725 179.305 1.00 98.51  ? 257 THR R O   1 
ATOM   7135 C CB  . THR D 4 393 ? 151.369 130.496 182.044 1.00 99.37  ? 257 THR R CB  1 
ATOM   7136 O OG1 . THR D 4 393 ? 150.251 131.000 182.784 1.00 99.32  ? 257 THR R OG1 1 
ATOM   7137 C CG2 . THR D 4 393 ? 152.637 131.181 182.522 1.00 98.51  ? 257 THR R CG2 1 
ATOM   7138 N N   . ILE D 4 394 ? 149.039 129.654 180.034 1.00 100.11 ? 258 ILE R N   1 
ATOM   7139 C CA  . ILE D 4 394 ? 148.228 128.625 179.387 1.00 100.03 ? 258 ILE R CA  1 
ATOM   7140 C C   . ILE D 4 394 ? 148.339 128.720 177.869 1.00 100.21 ? 258 ILE R C   1 
ATOM   7141 O O   . ILE D 4 394 ? 148.396 127.698 177.175 1.00 99.77  ? 258 ILE R O   1 
ATOM   7142 C CB  . ILE D 4 394 ? 146.766 128.709 179.859 1.00 98.48  ? 258 ILE R CB  1 
ATOM   7143 C CG1 . ILE D 4 394 ? 146.682 128.497 181.371 1.00 98.80  ? 258 ILE R CG1 1 
ATOM   7144 C CG2 . ILE D 4 394 ? 145.916 127.685 179.133 1.00 98.04  ? 258 ILE R CG2 1 
ATOM   7145 C CD1 . ILE D 4 394 ? 147.508 127.328 181.869 1.00 98.94  ? 258 ILE R CD1 1 
ATOM   7146 N N   . ILE D 4 395 ? 148.367 129.940 177.324 1.00 99.55  ? 259 ILE R N   1 
ATOM   7147 C CA  . ILE D 4 395 ? 148.530 130.088 175.879 1.00 97.49  ? 259 ILE R CA  1 
ATOM   7148 C C   . ILE D 4 395 ? 149.883 129.543 175.440 1.00 95.83  ? 259 ILE R C   1 
ATOM   7149 O O   . ILE D 4 395 ? 149.991 128.851 174.420 1.00 97.02  ? 259 ILE R O   1 
ATOM   7150 C CB  . ILE D 4 395 ? 148.352 131.558 175.459 1.00 98.93  ? 259 ILE R CB  1 
ATOM   7151 C CG1 . ILE D 4 395 ? 146.881 131.967 175.539 1.00 98.25  ? 259 ILE R CG1 1 
ATOM   7152 C CG2 . ILE D 4 395 ? 148.853 131.759 174.037 1.00 97.88  ? 259 ILE R CG2 1 
ATOM   7153 C CD1 . ILE D 4 395 ? 146.539 133.174 174.693 1.00 97.54  ? 259 ILE R CD1 1 
ATOM   7154 N N   . ALA D 4 396 ? 150.935 129.843 176.204 1.00 93.90  ? 260 ALA R N   1 
ATOM   7155 C CA  . ALA D 4 396 ? 152.266 129.347 175.869 1.00 96.56  ? 260 ALA R CA  1 
ATOM   7156 C C   . ALA D 4 396 ? 152.315 127.825 175.910 1.00 98.92  ? 260 ALA R C   1 
ATOM   7157 O O   . ALA D 4 396 ? 152.928 127.193 175.042 1.00 97.40  ? 260 ALA R O   1 
ATOM   7158 C CB  . ALA D 4 396 ? 153.304 129.943 176.818 1.00 94.71  ? 260 ALA R CB  1 
ATOM   7159 N N   . ASN D 4 397 ? 151.681 127.220 176.918 1.00 98.91  ? 261 ASN R N   1 
ATOM   7160 C CA  . ASN D 4 397 ? 151.620 125.764 176.983 1.00 96.32  ? 261 ASN R CA  1 
ATOM   7161 C C   . ASN D 4 397 ? 150.856 125.191 175.795 1.00 96.18  ? 261 ASN R C   1 
ATOM   7162 O O   . ASN D 4 397 ? 151.265 124.177 175.215 1.00 95.39  ? 261 ASN R O   1 
ATOM   7163 C CB  . ASN D 4 397 ? 150.980 125.323 178.298 1.00 95.62  ? 261 ASN R CB  1 
ATOM   7164 N N   . LYS D 4 398 ? 149.739 125.822 175.423 1.00 93.71  ? 262 LYS R N   1 
ATOM   7165 C CA  . LYS D 4 398 ? 148.982 125.372 174.258 1.00 92.58  ? 262 LYS R CA  1 
ATOM   7166 C C   . LYS D 4 398 ? 149.769 125.578 172.969 1.00 93.34  ? 262 LYS R C   1 
ATOM   7167 O O   . LYS D 4 398 ? 149.786 124.700 172.099 1.00 92.52  ? 262 LYS R O   1 
ATOM   7168 C CB  . LYS D 4 398 ? 147.642 126.102 174.191 1.00 91.45  ? 262 LYS R CB  1 
ATOM   7169 N N   . LEU D 4 399 ? 150.425 126.732 172.826 1.00 95.97  ? 263 LEU R N   1 
ATOM   7170 C CA  . LEU D 4 399 ? 151.232 126.986 171.639 1.00 95.23  ? 263 LEU R CA  1 
ATOM   7171 C C   . LEU D 4 399 ? 152.505 126.151 171.616 1.00 93.86  ? 263 LEU R C   1 
ATOM   7172 O O   . LEU D 4 399 ? 153.133 126.030 170.559 1.00 92.45  ? 263 LEU R O   1 
ATOM   7173 C CB  . LEU D 4 399 ? 151.580 128.473 171.545 1.00 94.83  ? 263 LEU R CB  1 
ATOM   7174 N N   . THR D 4 400 ? 152.905 125.581 172.756 1.00 96.57  ? 264 THR R N   1 
ATOM   7175 C CA  . THR D 4 400 ? 154.067 124.702 172.783 1.00 97.95  ? 264 THR R CA  1 
ATOM   7176 C C   . THR D 4 400 ? 153.778 123.347 172.152 1.00 97.26  ? 264 THR R C   1 
ATOM   7177 O O   . THR D 4 400 ? 154.720 122.617 171.825 1.00 96.12  ? 264 THR R O   1 
ATOM   7178 C CB  . THR D 4 400 ? 154.553 124.507 174.220 1.00 96.35  ? 264 THR R CB  1 
ATOM   7179 N N   . VAL D 4 401 ? 152.502 122.993 171.983 1.00 95.52  ? 265 VAL R N   1 
ATOM   7180 C CA  . VAL D 4 401 ? 152.157 121.732 171.333 1.00 95.97  ? 265 VAL R CA  1 
ATOM   7181 C C   . VAL D 4 401 ? 152.615 121.739 169.881 1.00 95.96  ? 265 VAL R C   1 
ATOM   7182 O O   . VAL D 4 401 ? 153.153 120.745 169.378 1.00 96.25  ? 265 VAL R O   1 
ATOM   7183 C CB  . VAL D 4 401 ? 150.645 121.465 171.449 1.00 94.99  ? 265 VAL R CB  1 
ATOM   7184 N N   . MET D 4 402 ? 152.399 122.855 169.180 1.00 92.60  ? 266 MET R N   1 
ATOM   7185 C CA  . MET D 4 402 ? 152.867 122.964 167.802 1.00 92.90  ? 266 MET R CA  1 
ATOM   7186 C C   . MET D 4 402 ? 154.388 122.906 167.731 1.00 93.97  ? 266 MET R C   1 
ATOM   7187 O O   . MET D 4 402 ? 154.949 122.240 166.852 1.00 93.92  ? 266 MET R O   1 
ATOM   7188 C CB  . MET D 4 402 ? 152.347 124.257 167.173 1.00 91.82  ? 266 MET R CB  1 
ATOM   7189 N N   . VAL D 4 403 ? 155.067 123.593 168.647 1.00 95.40  ? 267 VAL R N   1 
ATOM   7190 C CA  . VAL D 4 403 ? 156.528 123.602 168.726 1.00 94.58  ? 267 VAL R CA  1 
ATOM   7191 C C   . VAL D 4 403 ? 157.159 124.037 167.407 1.00 94.41  ? 267 VAL R C   1 
ATOM   7192 O O   . VAL D 4 403 ? 158.346 123.813 167.172 1.00 94.26  ? 267 VAL R O   1 
ATOM   7193 C CB  . VAL D 4 403 ? 157.071 122.226 169.155 1.00 92.94  ? 267 VAL R CB  1 
ATOM   7194 N N   . ARG D 4 435 ? 159.655 136.377 163.910 1.00 102.20 ? 299 ARG R N   1 
ATOM   7195 C CA  . ARG D 4 435 ? 159.127 136.721 165.225 1.00 102.23 ? 299 ARG R CA  1 
ATOM   7196 C C   . ARG D 4 435 ? 159.435 135.628 166.242 1.00 104.49 ? 299 ARG R C   1 
ATOM   7197 O O   . ARG D 4 435 ? 159.698 134.483 165.875 1.00 105.48 ? 299 ARG R O   1 
ATOM   7198 C CB  . ARG D 4 435 ? 157.618 136.959 165.151 1.00 101.72 ? 299 ARG R CB  1 
ATOM   7199 N N   . HIS D 4 436 ? 159.413 135.995 167.525 1.00 103.08 ? 300 HIS R N   1 
ATOM   7200 C CA  . HIS D 4 436 ? 159.651 135.013 168.578 1.00 102.65 ? 300 HIS R CA  1 
ATOM   7201 C C   . HIS D 4 436 ? 158.541 133.970 168.623 1.00 102.47 ? 300 HIS R C   1 
ATOM   7202 O O   . HIS D 4 436 ? 158.809 132.778 168.814 1.00 101.38 ? 300 HIS R O   1 
ATOM   7203 C CB  . HIS D 4 436 ? 159.787 135.714 169.929 1.00 100.95 ? 300 HIS R CB  1 
ATOM   7204 N N   . GLY D 4 437 ? 157.292 134.397 168.454 1.00 101.61 ? 301 GLY R N   1 
ATOM   7205 C CA  . GLY D 4 437 ? 156.173 133.476 168.465 1.00 102.25 ? 301 GLY R CA  1 
ATOM   7206 C C   . GLY D 4 437 ? 155.623 133.227 169.853 1.00 102.43 ? 301 GLY R C   1 
ATOM   7207 O O   . GLY D 4 437 ? 154.819 134.011 170.362 1.00 101.06 ? 301 GLY R O   1 
ATOM   7208 N N   . VAL D 4 438 ? 156.043 132.120 170.471 1.00 102.11 ? 302 VAL R N   1 
ATOM   7209 C CA  . VAL D 4 438 ? 155.628 131.812 171.838 1.00 100.94 ? 302 VAL R CA  1 
ATOM   7210 C C   . VAL D 4 438 ? 156.506 132.488 172.877 1.00 99.88  ? 302 VAL R C   1 
ATOM   7211 O O   . VAL D 4 438 ? 156.137 132.530 174.057 1.00 100.23 ? 302 VAL R O   1 
ATOM   7212 C CB  . VAL D 4 438 ? 155.635 130.289 172.073 1.00 101.59 ? 302 VAL R CB  1 
ATOM   7213 C CG1 . VAL D 4 438 ? 155.323 129.966 173.529 1.00 99.89  ? 302 VAL R CG1 1 
ATOM   7214 C CG2 . VAL D 4 438 ? 154.648 129.601 171.141 1.00 100.33 ? 302 VAL R CG2 1 
ATOM   7215 N N   . ARG D 4 439 ? 157.652 133.035 172.472 1.00 99.40  ? 303 ARG R N   1 
ATOM   7216 C CA  . ARG D 4 439 ? 158.607 133.626 173.397 1.00 99.59  ? 303 ARG R CA  1 
ATOM   7217 C C   . ARG D 4 439 ? 158.296 135.084 173.718 1.00 101.05 ? 303 ARG R C   1 
ATOM   7218 O O   . ARG D 4 439 ? 159.144 135.775 174.294 1.00 100.94 ? 303 ARG R O   1 
ATOM   7219 C CB  . ARG D 4 439 ? 160.026 133.505 172.837 1.00 98.45  ? 303 ARG R CB  1 
ATOM   7220 N N   . VAL D 4 440 ? 157.107 135.566 173.362 1.00 102.86 ? 304 VAL R N   1 
ATOM   7221 C CA  . VAL D 4 440 ? 156.708 136.923 173.691 1.00 101.56 ? 304 VAL R CA  1 
ATOM   7222 C C   . VAL D 4 440 ? 155.773 136.974 174.892 1.00 99.75  ? 304 VAL R C   1 
ATOM   7223 O O   . VAL D 4 440 ? 155.740 137.995 175.588 1.00 101.03 ? 304 VAL R O   1 
ATOM   7224 C CB  . VAL D 4 440 ? 156.069 137.631 172.479 1.00 100.33 ? 304 VAL R CB  1 
ATOM   7225 C CG1 . VAL D 4 440 ? 157.135 137.990 171.456 1.00 100.07 ? 304 VAL R CG1 1 
ATOM   7226 C CG2 . VAL D 4 440 ? 154.981 136.766 171.867 1.00 101.11 ? 304 VAL R CG2 1 
ATOM   7227 N N   . LEU D 4 441 ? 155.019 135.917 175.159 1.00 95.29  ? 305 LEU R N   1 
ATOM   7228 C CA  . LEU D 4 441 ? 154.201 135.911 176.367 1.00 95.85  ? 305 LEU R CA  1 
ATOM   7229 C C   . LEU D 4 441 ? 155.016 135.671 177.615 1.00 95.86  ? 305 LEU R C   1 
ATOM   7230 O O   . LEU D 4 441 ? 154.502 135.856 178.725 1.00 93.61  ? 305 LEU R O   1 
ATOM   7231 C CB  . LEU D 4 441 ? 153.097 134.859 176.253 1.00 95.56  ? 305 LEU R CB  1 
ATOM   7232 C CG  . LEU D 4 441 ? 152.121 134.989 175.082 1.00 94.82  ? 305 LEU R CG  1 
ATOM   7233 C CD1 . LEU D 4 441 ? 150.815 134.323 175.439 1.00 94.26  ? 305 LEU R CD1 1 
ATOM   7234 C CD2 . LEU D 4 441 ? 151.883 136.442 174.696 1.00 95.24  ? 305 LEU R CD2 1 
ATOM   7235 N N   . ARG D 4 442 ? 156.273 135.259 177.450 1.00 100.13 ? 306 ARG R N   1 
ATOM   7236 C CA  . ARG D 4 442 ? 157.215 135.160 178.556 1.00 99.71  ? 306 ARG R CA  1 
ATOM   7237 C C   . ARG D 4 442 ? 157.850 136.495 178.905 1.00 98.94  ? 306 ARG R C   1 
ATOM   7238 O O   . ARG D 4 442 ? 158.426 136.632 179.988 1.00 99.43  ? 306 ARG R O   1 
ATOM   7239 C CB  . ARG D 4 442 ? 158.319 134.149 178.228 1.00 97.74  ? 306 ARG R CB  1 
ATOM   7240 N N   . ALA D 4 443 ? 157.762 137.475 178.008 1.00 97.32  ? 307 ALA R N   1 
ATOM   7241 C CA  . ALA D 4 443 ? 158.173 138.838 178.305 1.00 97.49  ? 307 ALA R CA  1 
ATOM   7242 C C   . ALA D 4 443 ? 156.997 139.762 178.590 1.00 97.33  ? 307 ALA R C   1 
ATOM   7243 O O   . ALA D 4 443 ? 157.179 140.771 179.277 1.00 99.65  ? 307 ALA R O   1 
ATOM   7244 C CB  . ALA D 4 443 ? 158.997 139.412 177.147 1.00 97.59  ? 307 ALA R CB  1 
ATOM   7245 N N   . VAL D 4 444 ? 155.806 139.442 178.078 1.00 94.82  ? 308 VAL R N   1 
ATOM   7246 C CA  . VAL D 4 444 ? 154.627 140.260 178.346 1.00 94.39  ? 308 VAL R CA  1 
ATOM   7247 C C   . VAL D 4 444 ? 154.287 140.232 179.830 1.00 96.07  ? 308 VAL R C   1 
ATOM   7248 O O   . VAL D 4 444 ? 154.111 141.279 180.465 1.00 97.21  ? 308 VAL R O   1 
ATOM   7249 C CB  . VAL D 4 444 ? 153.437 139.777 177.497 1.00 95.09  ? 308 VAL R CB  1 
ATOM   7250 C CG1 . VAL D 4 444 ? 152.128 140.245 178.104 1.00 96.19  ? 308 VAL R CG1 1 
ATOM   7251 C CG2 . VAL D 4 444 ? 153.565 140.263 176.069 1.00 95.94  ? 308 VAL R CG2 1 
ATOM   7252 N N   . VAL D 4 445 ? 154.191 139.034 180.404 1.00 94.87  ? 309 VAL R N   1 
ATOM   7253 C CA  . VAL D 4 445 ? 153.882 138.915 181.823 1.00 94.93  ? 309 VAL R CA  1 
ATOM   7254 C C   . VAL D 4 445 ? 155.064 139.368 182.667 1.00 94.45  ? 309 VAL R C   1 
ATOM   7255 O O   . VAL D 4 445 ? 154.880 139.974 183.729 1.00 94.79  ? 309 VAL R O   1 
ATOM   7256 C CB  . VAL D 4 445 ? 153.461 137.473 182.151 1.00 93.91  ? 309 VAL R CB  1 
ATOM   7257 C CG1 . VAL D 4 445 ? 153.414 137.250 183.650 1.00 92.84  ? 309 VAL R CG1 1 
ATOM   7258 C CG2 . VAL D 4 445 ? 152.121 137.176 181.525 1.00 92.92  ? 309 VAL R CG2 1 
ATOM   7259 N N   . ILE D 4 446 ? 156.288 139.092 182.212 1.00 91.92  ? 310 ILE R N   1 
ATOM   7260 C CA  . ILE D 4 446 ? 157.464 139.595 182.910 1.00 93.37  ? 310 ILE R CA  1 
ATOM   7261 C C   . ILE D 4 446 ? 157.484 141.117 182.907 1.00 96.12  ? 310 ILE R C   1 
ATOM   7262 O O   . ILE D 4 446 ? 157.832 141.736 183.918 1.00 96.91  ? 310 ILE R O   1 
ATOM   7263 C CB  . ILE D 4 446 ? 158.743 139.013 182.285 1.00 93.43  ? 310 ILE R CB  1 
ATOM   7264 N N   . ALA D 4 447 ? 157.104 141.746 181.789 1.00 96.30  ? 311 ALA R N   1 
ATOM   7265 C CA  . ALA D 4 447 ? 157.074 143.205 181.720 1.00 93.85  ? 311 ALA R CA  1 
ATOM   7266 C C   . ALA D 4 447 ? 156.089 143.784 182.726 1.00 95.69  ? 311 ALA R C   1 
ATOM   7267 O O   . ALA D 4 447 ? 156.377 144.790 183.381 1.00 98.18  ? 311 ALA R O   1 
ATOM   7268 C CB  . ALA D 4 447 ? 156.716 143.665 180.304 1.00 92.44  ? 311 ALA R CB  1 
ATOM   7269 N N   . PHE D 4 448 ? 154.921 143.159 182.861 1.00 92.03  ? 312 PHE R N   1 
ATOM   7270 C CA  . PHE D 4 448 ? 153.933 143.625 183.825 1.00 90.14  ? 312 PHE R CA  1 
ATOM   7271 C C   . PHE D 4 448 ? 154.480 143.573 185.247 1.00 91.25  ? 312 PHE R C   1 
ATOM   7272 O O   . PHE D 4 448 ? 154.368 144.540 186.004 1.00 96.18  ? 312 PHE R O   1 
ATOM   7273 C CB  . PHE D 4 448 ? 152.657 142.790 183.705 1.00 89.38  ? 312 PHE R CB  1 
ATOM   7274 N N   . VAL D 4 449 ? 155.085 142.445 185.625 1.00 92.33  ? 313 VAL R N   1 
ATOM   7275 C CA  . VAL D 4 449 ? 155.477 142.241 187.015 1.00 93.59  ? 313 VAL R CA  1 
ATOM   7276 C C   . VAL D 4 449 ? 156.669 143.090 187.443 1.00 95.07  ? 313 VAL R C   1 
ATOM   7277 O O   . VAL D 4 449 ? 156.745 143.460 188.619 1.00 98.97  ? 313 VAL R O   1 
ATOM   7278 C CB  . VAL D 4 449 ? 155.777 140.759 187.259 1.00 93.61  ? 313 VAL R CB  1 
ATOM   7279 N N   . VAL D 4 450 ? 157.587 143.421 186.534 1.00 93.47  ? 314 VAL R N   1 
ATOM   7280 C CA  . VAL D 4 450 ? 158.806 144.119 186.940 1.00 95.98  ? 314 VAL R CA  1 
ATOM   7281 C C   . VAL D 4 450 ? 158.500 145.580 187.253 1.00 96.05  ? 314 VAL R C   1 
ATOM   7282 O O   . VAL D 4 450 ? 159.158 146.205 188.092 1.00 96.96  ? 314 VAL R O   1 
ATOM   7283 C CB  . VAL D 4 450 ? 159.902 143.983 185.864 1.00 95.81  ? 314 VAL R CB  1 
ATOM   7284 C CG1 . VAL D 4 450 ? 159.357 144.281 184.492 1.00 95.11  ? 314 VAL R CG1 1 
ATOM   7285 C CG2 . VAL D 4 450 ? 161.099 144.864 186.173 1.00 94.85  ? 314 VAL R CG2 1 
ATOM   7286 N N   . CYS D 4 451 ? 157.488 146.146 186.592 1.00 97.52  ? 315 CYS R N   1 
ATOM   7287 C CA  . CYS D 4 451 ? 157.228 147.577 186.730 1.00 97.82  ? 315 CYS R CA  1 
ATOM   7288 C C   . CYS D 4 451 ? 156.050 147.856 187.659 1.00 99.43  ? 315 CYS R C   1 
ATOM   7289 O O   . CYS D 4 451 ? 156.118 148.749 188.511 1.00 102.27 ? 315 CYS R O   1 
ATOM   7290 C CB  . CYS D 4 451 ? 156.989 148.196 185.356 1.00 97.36  ? 315 CYS R CB  1 
ATOM   7291 S SG  . CYS D 4 451 ? 158.006 147.500 184.044 1.00 98.49  ? 315 CYS R SG  1 
ATOM   7292 N N   . TRP D 4 452 ? 154.950 147.118 187.496 1.00 97.66  ? 316 TRP R N   1 
ATOM   7293 C CA  . TRP D 4 452 ? 153.753 147.357 188.296 1.00 96.11  ? 316 TRP R CA  1 
ATOM   7294 C C   . TRP D 4 452 ? 154.002 147.179 189.791 1.00 96.47  ? 316 TRP R C   1 
ATOM   7295 O O   . TRP D 4 452 ? 153.669 148.053 190.600 1.00 99.01  ? 316 TRP R O   1 
ATOM   7296 C CB  . TRP D 4 452 ? 152.629 146.424 187.833 1.00 95.32  ? 316 TRP R CB  1 
ATOM   7297 C CG  . TRP D 4 452 ? 151.504 147.100 187.106 1.00 97.04  ? 316 TRP R CG  1 
ATOM   7298 C CD1 . TRP D 4 452 ? 150.172 146.949 187.355 1.00 98.41  ? 316 TRP R CD1 1 
ATOM   7299 C CD2 . TRP D 4 452 ? 151.602 148.010 185.999 1.00 97.60  ? 316 TRP R CD2 1 
ATOM   7300 N NE1 . TRP D 4 452 ? 149.435 147.715 186.488 1.00 98.65  ? 316 TRP R NE1 1 
ATOM   7301 C CE2 . TRP D 4 452 ? 150.288 148.376 185.645 1.00 98.86  ? 316 TRP R CE2 1 
ATOM   7302 C CE3 . TRP D 4 452 ? 152.668 148.555 185.278 1.00 97.00  ? 316 TRP R CE3 1 
ATOM   7303 C CZ2 . TRP D 4 452 ? 150.013 149.261 184.604 1.00 97.87  ? 316 TRP R CZ2 1 
ATOM   7304 C CZ3 . TRP D 4 452 ? 152.391 149.435 184.247 1.00 97.96  ? 316 TRP R CZ3 1 
ATOM   7305 C CH2 . TRP D 4 452 ? 151.076 149.778 183.919 1.00 97.06  ? 316 TRP R CH2 1 
ATOM   7306 N N   . LEU D 4 453 ? 154.588 146.047 190.170 1.00 93.75  ? 317 LEU R N   1 
ATOM   7307 C CA  . LEU D 4 453 ? 154.727 145.665 191.572 1.00 96.61  ? 317 LEU R CA  1 
ATOM   7308 C C   . LEU D 4 453 ? 155.572 146.634 192.398 1.00 96.69  ? 317 LEU R C   1 
ATOM   7309 O O   . LEU D 4 453 ? 155.180 146.955 193.526 1.00 96.92  ? 317 LEU R O   1 
ATOM   7310 C CB  . LEU D 4 453 ? 155.292 144.247 191.681 1.00 96.05  ? 317 LEU R CB  1 
ATOM   7311 C CG  . LEU D 4 453 ? 154.245 143.168 191.973 1.00 94.85  ? 317 LEU R CG  1 
ATOM   7312 C CD1 . LEU D 4 453 ? 153.181 143.132 190.887 1.00 94.39  ? 317 LEU R CD1 1 
ATOM   7313 C CD2 . LEU D 4 453 ? 154.899 141.806 192.134 1.00 95.69  ? 317 LEU R CD2 1 
ATOM   7314 N N   . PRO D 4 454 ? 156.737 147.100 191.922 1.00 99.74  ? 318 PRO R N   1 
ATOM   7315 C CA  . PRO D 4 454 ? 157.491 148.078 192.728 1.00 100.91 ? 318 PRO R CA  1 
ATOM   7316 C C   . PRO D 4 454 ? 156.740 149.378 192.975 1.00 100.53 ? 318 PRO R C   1 
ATOM   7317 O O   . PRO D 4 454 ? 156.935 150.010 194.020 1.00 98.67  ? 318 PRO R O   1 
ATOM   7318 C CB  . PRO D 4 454 ? 158.768 148.300 191.906 1.00 99.04  ? 318 PRO R CB  1 
ATOM   7319 C CG  . PRO D 4 454 ? 158.410 147.899 190.536 1.00 99.16  ? 318 PRO R CG  1 
ATOM   7320 C CD  . PRO D 4 454 ? 157.476 146.745 190.699 1.00 97.34  ? 318 PRO R CD  1 
ATOM   7321 N N   . TYR D 4 455 ? 155.896 149.806 192.036 1.00 99.87  ? 319 TYR R N   1 
ATOM   7322 C CA  . TYR D 4 455 ? 155.096 151.001 192.278 1.00 99.01  ? 319 TYR R CA  1 
ATOM   7323 C C   . TYR D 4 455 ? 153.934 150.694 193.216 1.00 98.52  ? 319 TYR R C   1 
ATOM   7324 O O   . TYR D 4 455 ? 153.601 151.508 194.084 1.00 98.64  ? 319 TYR R O   1 
ATOM   7325 C CB  . TYR D 4 455 ? 154.598 151.578 190.949 1.00 97.34  ? 319 TYR R CB  1 
ATOM   7326 C CG  . TYR D 4 455 ? 153.387 152.485 191.050 1.00 98.24  ? 319 TYR R CG  1 
ATOM   7327 C CD1 . TYR D 4 455 ? 153.357 153.551 191.941 1.00 99.40  ? 319 TYR R CD1 1 
ATOM   7328 C CD2 . TYR D 4 455 ? 152.276 152.277 190.248 1.00 97.59  ? 319 TYR R CD2 1 
ATOM   7329 C CE1 . TYR D 4 455 ? 152.254 154.374 192.033 1.00 98.02  ? 319 TYR R CE1 1 
ATOM   7330 C CE2 . TYR D 4 455 ? 151.168 153.094 190.334 1.00 97.08  ? 319 TYR R CE2 1 
ATOM   7331 C CZ  . TYR D 4 455 ? 151.162 154.142 191.226 1.00 98.55  ? 319 TYR R CZ  1 
ATOM   7332 O OH  . TYR D 4 455 ? 150.060 154.959 191.312 1.00 99.83  ? 319 TYR R OH  1 
ATOM   7333 N N   . HIS D 4 456 ? 153.324 149.518 193.077 1.00 96.75  ? 320 HIS R N   1 
ATOM   7334 C CA  . HIS D 4 456 ? 152.176 149.172 193.903 1.00 96.88  ? 320 HIS R CA  1 
ATOM   7335 C C   . HIS D 4 456 ? 152.563 148.724 195.305 1.00 98.54  ? 320 HIS R C   1 
ATOM   7336 O O   . HIS D 4 456 ? 151.678 148.573 196.152 1.00 100.38 ? 320 HIS R O   1 
ATOM   7337 C CB  . HIS D 4 456 ? 151.344 148.088 193.217 1.00 95.99  ? 320 HIS R CB  1 
ATOM   7338 C CG  . HIS D 4 456 ? 150.540 148.596 192.064 1.00 98.36  ? 320 HIS R CG  1 
ATOM   7339 N ND1 . HIS D 4 456 ? 150.904 149.700 191.325 1.00 100.32 ? 320 HIS R ND1 1 
ATOM   7340 C CD2 . HIS D 4 456 ? 149.383 148.148 191.522 1.00 98.43  ? 320 HIS R CD2 1 
ATOM   7341 C CE1 . HIS D 4 456 ? 150.006 149.911 190.380 1.00 99.63  ? 320 HIS R CE1 1 
ATOM   7342 N NE2 . HIS D 4 456 ? 149.073 148.982 190.476 1.00 99.67  ? 320 HIS R NE2 1 
ATOM   7343 N N   . VAL D 4 457 ? 153.848 148.502 195.569 1.00 102.28 ? 321 VAL R N   1 
ATOM   7344 C CA  . VAL D 4 457 ? 154.285 148.253 196.938 1.00 104.13 ? 321 VAL R CA  1 
ATOM   7345 C C   . VAL D 4 457 ? 154.641 149.560 197.645 1.00 105.05 ? 321 VAL R C   1 
ATOM   7346 O O   . VAL D 4 457 ? 154.536 149.647 198.873 1.00 104.59 ? 321 VAL R O   1 
ATOM   7347 C CB  . VAL D 4 457 ? 155.462 147.260 196.963 1.00 103.16 ? 321 VAL R CB  1 
ATOM   7348 C CG1 . VAL D 4 457 ? 156.689 147.859 196.313 1.00 102.31 ? 321 VAL R CG1 1 
ATOM   7349 C CG2 . VAL D 4 457 ? 155.768 146.818 198.386 1.00 102.72 ? 321 VAL R CG2 1 
ATOM   7350 N N   . ARG D 4 458 ? 155.048 150.587 196.892 1.00 108.10 ? 322 ARG R N   1 
ATOM   7351 C CA  . ARG D 4 458 ? 155.226 151.911 197.478 1.00 107.03 ? 322 ARG R CA  1 
ATOM   7352 C C   . ARG D 4 458 ? 153.902 152.454 197.998 1.00 106.39 ? 322 ARG R C   1 
ATOM   7353 O O   . ARG D 4 458 ? 153.854 153.095 199.054 1.00 105.28 ? 322 ARG R O   1 
ATOM   7354 C CB  . ARG D 4 458 ? 155.835 152.864 196.449 1.00 106.10 ? 322 ARG R CB  1 
ATOM   7355 C CG  . ARG D 4 458 ? 156.019 154.292 196.941 1.00 105.04 ? 322 ARG R CG  1 
ATOM   7356 C CD  . ARG D 4 458 ? 156.883 154.342 198.189 1.00 106.16 ? 322 ARG R CD  1 
ATOM   7357 N NE  . ARG D 4 458 ? 156.568 155.489 199.033 1.00 107.33 ? 322 ARG R NE  1 
ATOM   7358 C CZ  . ARG D 4 458 ? 157.408 156.483 199.289 1.00 106.94 ? 322 ARG R CZ  1 
ATOM   7359 N NH1 . ARG D 4 458 ? 158.626 156.507 198.776 1.00 106.46 ? 322 ARG R NH1 1 
ATOM   7360 N NH2 . ARG D 4 458 ? 157.016 157.477 200.080 1.00 106.35 ? 322 ARG R NH2 1 
ATOM   7361 N N   . ARG D 4 459 ? 152.813 152.203 197.267 1.00 104.24 ? 323 ARG R N   1 
ATOM   7362 C CA  . ARG D 4 459 ? 151.487 152.571 197.747 1.00 103.10 ? 323 ARG R CA  1 
ATOM   7363 C C   . ARG D 4 459 ? 151.108 151.816 199.014 1.00 103.56 ? 323 ARG R C   1 
ATOM   7364 O O   . ARG D 4 459 ? 150.170 152.223 199.707 1.00 105.32 ? 323 ARG R O   1 
ATOM   7365 C CB  . ARG D 4 459 ? 150.444 152.320 196.657 1.00 101.63 ? 323 ARG R CB  1 
ATOM   7366 N N   . LEU D 4 460 ? 151.808 150.724 199.326 1.00 102.12 ? 324 LEU R N   1 
ATOM   7367 C CA  . LEU D 4 460 ? 151.584 149.986 200.559 1.00 102.90 ? 324 LEU R CA  1 
ATOM   7368 C C   . LEU D 4 460 ? 152.689 150.169 201.589 1.00 102.88 ? 324 LEU R C   1 
ATOM   7369 O O   . LEU D 4 460 ? 152.443 149.940 202.777 1.00 103.04 ? 324 LEU R O   1 
ATOM   7370 C CB  . LEU D 4 460 ? 151.422 148.489 200.262 1.00 102.90 ? 324 LEU R CB  1 
ATOM   7371 C CG  . LEU D 4 460 ? 150.219 148.128 199.391 1.00 101.74 ? 324 LEU R CG  1 
ATOM   7372 C CD1 . LEU D 4 460 ? 150.159 146.630 199.144 1.00 101.48 ? 324 LEU R CD1 1 
ATOM   7373 C CD2 . LEU D 4 460 ? 148.932 148.624 200.031 1.00 102.02 ? 324 LEU R CD2 1 
ATOM   7374 N N   . MET D 4 461 ? 153.888 150.574 201.170 1.00 101.73 ? 325 MET R N   1 
ATOM   7375 C CA  . MET D 4 461 ? 154.970 150.845 202.109 1.00 101.62 ? 325 MET R CA  1 
ATOM   7376 C C   . MET D 4 461 ? 154.819 152.186 202.813 1.00 103.64 ? 325 MET R C   1 
ATOM   7377 O O   . MET D 4 461 ? 155.525 152.433 203.796 1.00 102.85 ? 325 MET R O   1 
ATOM   7378 C CB  . MET D 4 461 ? 156.320 150.796 201.389 1.00 100.82 ? 325 MET R CB  1 
ATOM   7379 N N   . PHE D 4 462 ? 153.926 153.053 202.335 1.00 110.97 ? 326 PHE R N   1 
ATOM   7380 C CA  . PHE D 4 462 ? 153.680 154.348 202.958 1.00 110.00 ? 326 PHE R CA  1 
ATOM   7381 C C   . PHE D 4 462 ? 152.252 154.485 203.471 1.00 109.77 ? 326 PHE R C   1 
ATOM   7382 O O   . PHE D 4 462 ? 151.836 155.595 203.824 1.00 110.17 ? 326 PHE R O   1 
ATOM   7383 C CB  . PHE D 4 462 ? 153.993 155.481 201.976 1.00 107.86 ? 326 PHE R CB  1 
ATOM   7384 N N   . CYS D 4 463 ? 151.489 153.395 203.516 1.00 104.58 ? 327 CYS R N   1 
ATOM   7385 C CA  . CYS D 4 463 ? 150.122 153.413 204.017 1.00 104.37 ? 327 CYS R CA  1 
ATOM   7386 C C   . CYS D 4 463 ? 149.946 152.586 205.280 1.00 105.59 ? 327 CYS R C   1 
ATOM   7387 O O   . CYS D 4 463 ? 149.489 153.105 206.302 1.00 104.85 ? 327 CYS R O   1 
ATOM   7388 C CB  . CYS D 4 463 ? 149.157 152.913 202.931 1.00 103.86 ? 327 CYS R CB  1 
ATOM   7389 N N   . TYR D 4 464 ? 150.306 151.306 205.239 1.00 107.75 ? 328 TYR R N   1 
ATOM   7390 C CA  . TYR D 4 464 ? 150.164 150.418 206.385 1.00 107.29 ? 328 TYR R CA  1 
ATOM   7391 C C   . TYR D 4 464 ? 151.360 150.466 207.325 1.00 107.15 ? 328 TYR R C   1 
ATOM   7392 O O   . TYR D 4 464 ? 151.327 149.821 208.378 1.00 106.38 ? 328 TYR R O   1 
ATOM   7393 C CB  . TYR D 4 464 ? 149.940 148.978 205.911 1.00 104.77 ? 328 TYR R CB  1 
ATOM   7394 N N   . ILE D 4 465 ? 152.410 151.208 206.975 1.00 106.73 ? 329 ILE R N   1 
ATOM   7395 C CA  . ILE D 4 465 ? 153.580 151.304 207.838 1.00 106.01 ? 329 ILE R CA  1 
ATOM   7396 C C   . ILE D 4 465 ? 153.259 152.200 209.025 1.00 107.56 ? 329 ILE R C   1 
ATOM   7397 O O   . ILE D 4 465 ? 152.764 153.323 208.862 1.00 107.03 ? 329 ILE R O   1 
ATOM   7398 C CB  . ILE D 4 465 ? 154.789 151.831 207.051 1.00 105.58 ? 329 ILE R CB  1 
ATOM   7399 N N   . SER D 4 466 ? 153.537 151.706 210.228 1.00 112.19 ? 330 SER R N   1 
ATOM   7400 C CA  . SER D 4 466 ? 153.271 152.474 211.434 1.00 111.62 ? 330 SER R CA  1 
ATOM   7401 C C   . SER D 4 466 ? 154.276 153.614 211.577 1.00 112.47 ? 330 SER R C   1 
ATOM   7402 O O   . SER D 4 466 ? 155.324 153.645 210.926 1.00 112.71 ? 330 SER R O   1 
ATOM   7403 C CB  . SER D 4 466 ? 153.321 151.572 212.667 1.00 110.82 ? 330 SER R CB  1 
ATOM   7404 N N   . ASP D 4 467 ? 153.941 154.563 212.452 1.00 115.59 ? 331 ASP R N   1 
ATOM   7405 C CA  . ASP D 4 467 ? 154.787 155.731 212.699 1.00 116.09 ? 331 ASP R CA  1 
ATOM   7406 C C   . ASP D 4 467 ? 155.984 155.315 213.556 1.00 116.84 ? 331 ASP R C   1 
ATOM   7407 O O   . ASP D 4 467 ? 156.083 155.611 214.749 1.00 116.86 ? 331 ASP R O   1 
ATOM   7408 C CB  . ASP D 4 467 ? 153.984 156.844 213.357 1.00 115.04 ? 331 ASP R CB  1 
ATOM   7409 N N   . GLU D 4 468 ? 156.911 154.610 212.914 1.00 116.80 ? 332 GLU R N   1 
ATOM   7410 C CA  . GLU D 4 468 ? 158.100 154.109 213.588 1.00 116.58 ? 332 GLU R CA  1 
ATOM   7411 C C   . GLU D 4 468 ? 159.187 153.878 212.548 1.00 117.08 ? 332 GLU R C   1 
ATOM   7412 O O   . GLU D 4 468 ? 158.926 153.852 211.343 1.00 115.84 ? 332 GLU R O   1 
ATOM   7413 C CB  . GLU D 4 468 ? 157.802 152.825 214.368 1.00 115.02 ? 332 GLU R CB  1 
ATOM   7414 N N   . GLN D 4 469 ? 160.419 153.720 213.039 1.00 117.36 ? 333 GLN R N   1 
ATOM   7415 C CA  . GLN D 4 469 ? 161.586 153.433 212.202 1.00 116.91 ? 333 GLN R CA  1 
ATOM   7416 C C   . GLN D 4 469 ? 161.837 154.533 211.175 1.00 116.49 ? 333 GLN R C   1 
ATOM   7417 O O   . GLN D 4 469 ? 162.334 154.271 210.077 1.00 115.31 ? 333 GLN R O   1 
ATOM   7418 C CB  . GLN D 4 469 ? 161.453 152.074 211.507 1.00 114.59 ? 333 GLN R CB  1 
ATOM   7419 N N   . TRP D 4 470 ? 161.500 155.772 211.522 1.00 116.72 ? 334 TRP R N   1 
ATOM   7420 C CA  . TRP D 4 470 ? 161.729 156.899 210.630 1.00 116.75 ? 334 TRP R CA  1 
ATOM   7421 C C   . TRP D 4 470 ? 163.128 157.463 210.839 1.00 117.10 ? 334 TRP R C   1 
ATOM   7422 O O   . TRP D 4 470 ? 163.592 157.607 211.974 1.00 116.63 ? 334 TRP R O   1 
ATOM   7423 C CB  . TRP D 4 470 ? 160.684 157.988 210.865 1.00 116.13 ? 334 TRP R CB  1 
ATOM   7424 N N   . THR D 4 471 ? 163.801 157.779 209.734 1.00 118.29 ? 335 THR R N   1 
ATOM   7425 C CA  . THR D 4 471 ? 165.150 158.324 209.786 1.00 118.60 ? 335 THR R CA  1 
ATOM   7426 C C   . THR D 4 471 ? 165.409 159.097 208.504 1.00 118.70 ? 335 THR R C   1 
ATOM   7427 O O   . THR D 4 471 ? 164.747 158.844 207.491 1.00 118.17 ? 335 THR R O   1 
ATOM   7428 C CB  . THR D 4 471 ? 166.195 157.212 209.958 1.00 117.28 ? 335 THR R CB  1 
ATOM   7429 N N   . PRO D 4 472 ? 166.347 160.050 208.516 1.00 115.96 ? 336 PRO R N   1 
ATOM   7430 C CA  . PRO D 4 472 ? 166.677 160.753 207.263 1.00 115.50 ? 336 PRO R CA  1 
ATOM   7431 C C   . PRO D 4 472 ? 167.172 159.824 206.170 1.00 115.53 ? 336 PRO R C   1 
ATOM   7432 O O   . PRO D 4 472 ? 166.863 160.035 204.990 1.00 115.14 ? 336 PRO R O   1 
ATOM   7433 C CB  . PRO D 4 472 ? 167.757 161.751 207.702 1.00 114.08 ? 336 PRO R CB  1 
ATOM   7434 N N   . PHE D 4 473 ? 167.940 158.794 206.534 1.00 116.08 ? 337 PHE R N   1 
ATOM   7435 C CA  . PHE D 4 473 ? 168.331 157.787 205.554 1.00 116.52 ? 337 PHE R CA  1 
ATOM   7436 C C   . PHE D 4 473 ? 167.110 157.056 205.016 1.00 116.52 ? 337 PHE R C   1 
ATOM   7437 O O   . PHE D 4 473 ? 167.018 156.785 203.813 1.00 114.65 ? 337 PHE R O   1 
ATOM   7438 C CB  . PHE D 4 473 ? 169.320 156.801 206.177 1.00 115.48 ? 337 PHE R CB  1 
ATOM   7439 N N   . LEU D 4 474 ? 166.157 156.736 205.895 1.00 116.26 ? 338 LEU R N   1 
ATOM   7440 C CA  . LEU D 4 474 ? 164.905 156.138 205.445 1.00 115.20 ? 338 LEU R CA  1 
ATOM   7441 C C   . LEU D 4 474 ? 164.140 157.089 204.536 1.00 116.02 ? 338 LEU R C   1 
ATOM   7442 O O   . LEU D 4 474 ? 163.510 156.657 203.567 1.00 115.30 ? 338 LEU R O   1 
ATOM   7443 C CB  . LEU D 4 474 ? 164.050 155.739 206.648 1.00 113.89 ? 338 LEU R CB  1 
ATOM   7444 N N   . TYR D 4 475 ? 164.181 158.390 204.834 1.00 117.37 ? 339 TYR R N   1 
ATOM   7445 C CA  . TYR D 4 475 ? 163.510 159.371 203.986 1.00 116.67 ? 339 TYR R CA  1 
ATOM   7446 C C   . TYR D 4 475 ? 164.118 159.399 202.587 1.00 116.54 ? 339 TYR R C   1 
ATOM   7447 O O   . TYR D 4 475 ? 163.397 159.386 201.580 1.00 116.27 ? 339 TYR R O   1 
ATOM   7448 C CB  . TYR D 4 475 ? 163.586 160.754 204.634 1.00 115.50 ? 339 TYR R CB  1 
ATOM   7449 N N   . ASP D 4 476 ? 165.451 159.437 202.508 1.00 114.34 ? 340 ASP R N   1 
ATOM   7450 C CA  . ASP D 4 476 ? 166.116 159.429 201.208 1.00 114.56 ? 340 ASP R CA  1 
ATOM   7451 C C   . ASP D 4 476 ? 165.841 158.132 200.457 1.00 113.96 ? 340 ASP R C   1 
ATOM   7452 O O   . ASP D 4 476 ? 165.609 158.144 199.240 1.00 113.37 ? 340 ASP R O   1 
ATOM   7453 C CB  . ASP D 4 476 ? 167.619 159.639 201.386 1.00 113.27 ? 340 ASP R CB  1 
ATOM   7454 N N   . PHE D 4 477 ? 165.863 157.001 201.168 1.00 112.19 ? 341 PHE R N   1 
ATOM   7455 C CA  . PHE D 4 477 ? 165.571 155.721 200.535 1.00 113.54 ? 341 PHE R CA  1 
ATOM   7456 C C   . PHE D 4 477 ? 164.146 155.686 199.999 1.00 113.63 ? 341 PHE R C   1 
ATOM   7457 O O   . PHE D 4 477 ? 163.906 155.181 198.898 1.00 113.05 ? 341 PHE R O   1 
ATOM   7458 C CB  . PHE D 4 477 ? 165.802 154.581 201.525 1.00 112.89 ? 341 PHE R CB  1 
ATOM   7459 N N   . TYR D 4 478 ? 163.188 156.218 200.761 1.00 111.46 ? 342 TYR R N   1 
ATOM   7460 C CA  . TYR D 4 478 ? 161.804 156.248 200.300 1.00 110.24 ? 342 TYR R CA  1 
ATOM   7461 C C   . TYR D 4 478 ? 161.648 157.140 199.076 1.00 109.78 ? 342 TYR R C   1 
ATOM   7462 O O   . TYR D 4 478 ? 160.927 156.789 198.135 1.00 110.10 ? 342 TYR R O   1 
ATOM   7463 C CB  . TYR D 4 478 ? 160.884 156.714 201.428 1.00 107.81 ? 342 TYR R CB  1 
ATOM   7464 N N   . HIS D 4 479 ? 162.311 158.299 199.069 1.00 108.06 ? 343 HIS R N   1 
ATOM   7465 C CA  . HIS D 4 479 ? 162.228 159.181 197.908 1.00 107.96 ? 343 HIS R CA  1 
ATOM   7466 C C   . HIS D 4 479 ? 162.808 158.509 196.669 1.00 108.17 ? 343 HIS R C   1 
ATOM   7467 O O   . HIS D 4 479 ? 162.203 158.536 195.587 1.00 107.87 ? 343 HIS R O   1 
ATOM   7468 C CB  . HIS D 4 479 ? 162.951 160.497 198.198 1.00 106.96 ? 343 HIS R CB  1 
ATOM   7469 N N   . TYR D 4 480 ? 163.977 157.880 196.815 1.00 110.91 ? 344 TYR R N   1 
ATOM   7470 C CA  . TYR D 4 480 ? 164.588 157.187 195.686 1.00 111.54 ? 344 TYR R CA  1 
ATOM   7471 C C   . TYR D 4 480 ? 163.719 156.026 195.217 1.00 111.32 ? 344 TYR R C   1 
ATOM   7472 O O   . TYR D 4 480 ? 163.596 155.780 194.011 1.00 110.81 ? 344 TYR R O   1 
ATOM   7473 C CB  . TYR D 4 480 ? 165.985 156.698 196.065 1.00 110.81 ? 344 TYR R CB  1 
ATOM   7474 N N   . PHE D 4 481 ? 163.118 155.293 196.157 1.00 109.44 ? 345 PHE R N   1 
ATOM   7475 C CA  . PHE D 4 481 ? 162.248 154.182 195.794 1.00 109.49 ? 345 PHE R CA  1 
ATOM   7476 C C   . PHE D 4 481 ? 161.032 154.667 195.023 1.00 107.57 ? 345 PHE R C   1 
ATOM   7477 O O   . PHE D 4 481 ? 160.630 154.046 194.034 1.00 107.19 ? 345 PHE R O   1 
ATOM   7478 C CB  . PHE D 4 481 ? 161.819 153.420 197.048 1.00 109.66 ? 345 PHE R CB  1 
ATOM   7479 C CG  . PHE D 4 481 ? 160.974 152.214 196.762 1.00 109.19 ? 345 PHE R CG  1 
ATOM   7480 C CD1 . PHE D 4 481 ? 161.280 151.374 195.704 1.00 108.63 ? 345 PHE R CD1 1 
ATOM   7481 C CD2 . PHE D 4 481 ? 159.872 151.922 197.546 1.00 107.74 ? 345 PHE R CD2 1 
ATOM   7482 C CE1 . PHE D 4 481 ? 160.504 150.266 195.436 1.00 107.78 ? 345 PHE R CE1 1 
ATOM   7483 C CE2 . PHE D 4 481 ? 159.093 150.815 197.283 1.00 107.41 ? 345 PHE R CE2 1 
ATOM   7484 C CZ  . PHE D 4 481 ? 159.410 149.987 196.226 1.00 107.48 ? 345 PHE R CZ  1 
ATOM   7485 N N   . TYR D 4 482 ? 160.429 155.773 195.462 1.00 107.91 ? 346 TYR R N   1 
ATOM   7486 C CA  . TYR D 4 482 ? 159.298 156.325 194.726 1.00 108.82 ? 346 TYR R CA  1 
ATOM   7487 C C   . TYR D 4 482 ? 159.716 156.739 193.324 1.00 109.96 ? 346 TYR R C   1 
ATOM   7488 O O   . TYR D 4 482 ? 158.994 156.484 192.351 1.00 110.05 ? 346 TYR R O   1 
ATOM   7489 C CB  . TYR D 4 482 ? 158.697 157.515 195.477 1.00 109.03 ? 346 TYR R CB  1 
ATOM   7490 C CG  . TYR D 4 482 ? 158.202 158.617 194.564 1.00 109.11 ? 346 TYR R CG  1 
ATOM   7491 C CD1 . TYR D 4 482 ? 156.919 158.580 194.038 1.00 109.75 ? 346 TYR R CD1 1 
ATOM   7492 C CD2 . TYR D 4 482 ? 159.011 159.700 194.239 1.00 108.22 ? 346 TYR R CD2 1 
ATOM   7493 C CE1 . TYR D 4 482 ? 156.460 159.578 193.203 1.00 110.18 ? 346 TYR R CE1 1 
ATOM   7494 C CE2 . TYR D 4 482 ? 158.560 160.701 193.403 1.00 108.67 ? 346 TYR R CE2 1 
ATOM   7495 C CZ  . TYR D 4 482 ? 157.283 160.636 192.890 1.00 109.42 ? 346 TYR R CZ  1 
ATOM   7496 O OH  . TYR D 4 482 ? 156.827 161.633 192.060 1.00 109.56 ? 346 TYR R OH  1 
ATOM   7497 N N   . MET D 4 483 ? 160.880 157.384 193.201 1.00 108.13 ? 347 MET R N   1 
ATOM   7498 C CA  . MET D 4 483 ? 161.348 157.813 191.886 1.00 107.17 ? 347 MET R CA  1 
ATOM   7499 C C   . MET D 4 483 ? 161.557 156.619 190.962 1.00 110.25 ? 347 MET R C   1 
ATOM   7500 O O   . MET D 4 483 ? 161.115 156.626 189.807 1.00 110.21 ? 347 MET R O   1 
ATOM   7501 C CB  . MET D 4 483 ? 162.639 158.621 192.028 1.00 105.61 ? 347 MET R CB  1 
ATOM   7502 N N   . VAL D 4 484 ? 162.214 155.571 191.467 1.00 109.59 ? 348 VAL R N   1 
ATOM   7503 C CA  . VAL D 4 484 ? 162.488 154.392 190.651 1.00 106.21 ? 348 VAL R CA  1 
ATOM   7504 C C   . VAL D 4 484 ? 161.192 153.684 190.274 1.00 105.79 ? 348 VAL R C   1 
ATOM   7505 O O   . VAL D 4 484 ? 161.030 153.221 189.139 1.00 105.77 ? 348 VAL R O   1 
ATOM   7506 C CB  . VAL D 4 484 ? 163.455 153.447 191.386 1.00 105.66 ? 348 VAL R CB  1 
ATOM   7507 N N   . THR D 4 485 ? 160.255 153.578 191.219 1.00 105.91 ? 349 THR R N   1 
ATOM   7508 C CA  . THR D 4 485 ? 158.986 152.916 190.940 1.00 105.83 ? 349 THR R CA  1 
ATOM   7509 C C   . THR D 4 485 ? 158.184 153.673 189.890 1.00 106.39 ? 349 THR R C   1 
ATOM   7510 O O   . THR D 4 485 ? 157.599 153.060 188.990 1.00 105.35 ? 349 THR R O   1 
ATOM   7511 C CB  . THR D 4 485 ? 158.178 152.771 192.227 1.00 104.94 ? 349 THR R CB  1 
ATOM   7512 N N   . ASN D 4 486 ? 158.141 155.004 189.987 1.00 103.99 ? 350 ASN R N   1 
ATOM   7513 C CA  . ASN D 4 486 ? 157.423 155.784 188.985 1.00 102.61 ? 350 ASN R CA  1 
ATOM   7514 C C   . ASN D 4 486 ? 158.112 155.702 187.629 1.00 104.86 ? 350 ASN R C   1 
ATOM   7515 O O   . ASN D 4 486 ? 157.444 155.667 186.587 1.00 105.71 ? 350 ASN R O   1 
ATOM   7516 C CB  . ASN D 4 486 ? 157.291 157.234 189.445 1.00 102.04 ? 350 ASN R CB  1 
ATOM   7517 N N   . ALA D 4 487 ? 159.448 155.657 187.620 1.00 104.58 ? 351 ALA R N   1 
ATOM   7518 C CA  . ALA D 4 487 ? 160.168 155.464 186.366 1.00 104.81 ? 351 ALA R CA  1 
ATOM   7519 C C   . ALA D 4 487 ? 159.812 154.126 185.731 1.00 105.09 ? 351 ALA R C   1 
ATOM   7520 O O   . ALA D 4 487 ? 159.590 154.046 184.518 1.00 104.22 ? 351 ALA R O   1 
ATOM   7521 C CB  . ALA D 4 487 ? 161.674 155.561 186.603 1.00 103.47 ? 351 ALA R CB  1 
ATOM   7522 N N   . LEU D 4 488 ? 159.748 153.066 186.539 1.00 102.71 ? 352 LEU R N   1 
ATOM   7523 C CA  . LEU D 4 488 ? 159.363 151.758 186.017 1.00 101.76 ? 352 LEU R CA  1 
ATOM   7524 C C   . LEU D 4 488 ? 157.928 151.769 185.504 1.00 101.27 ? 352 LEU R C   1 
ATOM   7525 O O   . LEU D 4 488 ? 157.627 151.168 184.466 1.00 100.96 ? 352 LEU R O   1 
ATOM   7526 C CB  . LEU D 4 488 ? 159.541 150.690 187.096 1.00 100.51 ? 352 LEU R CB  1 
ATOM   7527 N N   . PHE D 4 489 ? 157.026 152.441 186.224 1.00 98.37  ? 353 PHE R N   1 
ATOM   7528 C CA  . PHE D 4 489 ? 155.640 152.532 185.777 1.00 97.92  ? 353 PHE R CA  1 
ATOM   7529 C C   . PHE D 4 489 ? 155.542 153.222 184.424 1.00 98.56  ? 353 PHE R C   1 
ATOM   7530 O O   . PHE D 4 489 ? 154.827 152.756 183.528 1.00 98.87  ? 353 PHE R O   1 
ATOM   7531 C CB  . PHE D 4 489 ? 154.804 153.275 186.816 1.00 97.01  ? 353 PHE R CB  1 
ATOM   7532 C CG  . PHE D 4 489 ? 153.351 152.903 186.802 1.00 98.58  ? 353 PHE R CG  1 
ATOM   7533 C CD1 . PHE D 4 489 ? 152.952 151.600 187.040 1.00 99.10  ? 353 PHE R CD1 1 
ATOM   7534 C CD2 . PHE D 4 489 ? 152.381 153.857 186.545 1.00 98.75  ? 353 PHE R CD2 1 
ATOM   7535 C CE1 . PHE D 4 489 ? 151.614 151.259 187.028 1.00 98.92  ? 353 PHE R CE1 1 
ATOM   7536 C CE2 . PHE D 4 489 ? 151.044 153.520 186.528 1.00 98.78  ? 353 PHE R CE2 1 
ATOM   7537 C CZ  . PHE D 4 489 ? 150.660 152.219 186.770 1.00 99.61  ? 353 PHE R CZ  1 
ATOM   7538 N N   . TYR D 4 490 ? 156.266 154.328 184.251 1.00 101.05 ? 354 TYR R N   1 
ATOM   7539 C CA  . TYR D 4 490 ? 156.227 155.031 182.974 1.00 102.06 ? 354 TYR R CA  1 
ATOM   7540 C C   . TYR D 4 490 ? 156.894 154.214 181.872 1.00 103.45 ? 354 TYR R C   1 
ATOM   7541 O O   . TYR D 4 490 ? 156.445 154.231 180.719 1.00 102.48 ? 354 TYR R O   1 
ATOM   7542 C CB  . TYR D 4 490 ? 156.880 156.404 183.116 1.00 101.15 ? 354 TYR R CB  1 
ATOM   7543 C CG  . TYR D 4 490 ? 156.070 157.355 183.965 1.00 101.71 ? 354 TYR R CG  1 
ATOM   7544 C CD1 . TYR D 4 490 ? 154.688 157.392 183.868 1.00 102.28 ? 354 TYR R CD1 1 
ATOM   7545 C CD2 . TYR D 4 490 ? 156.687 158.208 184.870 1.00 102.54 ? 354 TYR R CD2 1 
ATOM   7546 C CE1 . TYR D 4 490 ? 153.942 158.253 184.644 1.00 102.52 ? 354 TYR R CE1 1 
ATOM   7547 C CE2 . TYR D 4 490 ? 155.948 159.073 185.650 1.00 102.69 ? 354 TYR R CE2 1 
ATOM   7548 C CZ  . TYR D 4 490 ? 154.576 159.091 185.533 1.00 102.73 ? 354 TYR R CZ  1 
ATOM   7549 O OH  . TYR D 4 490 ? 153.835 159.951 186.309 1.00 102.64 ? 354 TYR R OH  1 
ATOM   7550 N N   . VAL D 4 491 ? 157.955 153.477 182.209 1.00 101.51 ? 355 VAL R N   1 
ATOM   7551 C CA  . VAL D 4 491 ? 158.602 152.615 181.224 1.00 100.38 ? 355 VAL R CA  1 
ATOM   7552 C C   . VAL D 4 491 ? 157.637 151.538 180.747 1.00 99.68  ? 355 VAL R C   1 
ATOM   7553 O O   . VAL D 4 491 ? 157.578 151.219 179.554 1.00 99.37  ? 355 VAL R O   1 
ATOM   7554 C CB  . VAL D 4 491 ? 159.888 152.004 181.809 1.00 98.93  ? 355 VAL R CB  1 
ATOM   7555 N N   . SER D 4 492 ? 156.879 150.952 181.673 1.00 93.99  ? 356 SER R N   1 
ATOM   7556 C CA  . SER D 4 492 ? 155.880 149.962 181.286 1.00 94.91  ? 356 SER R CA  1 
ATOM   7557 C C   . SER D 4 492 ? 154.778 150.590 180.445 1.00 93.34  ? 356 SER R C   1 
ATOM   7558 O O   . SER D 4 492 ? 154.306 149.985 179.476 1.00 93.13  ? 356 SER R O   1 
ATOM   7559 C CB  . SER D 4 492 ? 155.292 149.297 182.526 1.00 95.64  ? 356 SER R CB  1 
ATOM   7560 N N   . SER D 4 493 ? 154.347 151.799 180.806 1.00 93.84  ? 357 SER R N   1 
ATOM   7561 C CA  . SER D 4 493 ? 153.324 152.481 180.022 1.00 95.80  ? 357 SER R CA  1 
ATOM   7562 C C   . SER D 4 493 ? 153.828 152.892 178.645 1.00 95.25  ? 357 SER R C   1 
ATOM   7563 O O   . SER D 4 493 ? 153.014 153.167 177.757 1.00 93.26  ? 357 SER R O   1 
ATOM   7564 C CB  . SER D 4 493 ? 152.814 153.708 180.778 1.00 95.54  ? 357 SER R CB  1 
ATOM   7565 N N   . THR D 4 494 ? 155.146 152.953 178.453 1.00 93.33  ? 358 THR R N   1 
ATOM   7566 C CA  . THR D 4 494 ? 155.719 153.309 177.161 1.00 91.53  ? 358 THR R CA  1 
ATOM   7567 C C   . THR D 4 494 ? 156.173 152.112 176.333 1.00 91.82  ? 358 THR R C   1 
ATOM   7568 O O   . THR D 4 494 ? 156.362 152.258 175.122 1.00 90.28  ? 358 THR R O   1 
ATOM   7569 C CB  . THR D 4 494 ? 156.915 154.249 177.354 1.00 90.96  ? 358 THR R CB  1 
ATOM   7570 N N   . ILE D 4 495 ? 156.361 150.941 176.950 1.00 94.29  ? 359 ILE R N   1 
ATOM   7571 C CA  . ILE D 4 495 ? 156.934 149.796 176.240 1.00 93.51  ? 359 ILE R CA  1 
ATOM   7572 C C   . ILE D 4 495 ? 155.935 149.019 175.397 1.00 93.68  ? 359 ILE R C   1 
ATOM   7573 O O   . ILE D 4 495 ? 156.350 148.156 174.614 1.00 93.98  ? 359 ILE R O   1 
ATOM   7574 C CB  . ILE D 4 495 ? 157.595 148.815 177.227 1.00 91.35  ? 359 ILE R CB  1 
ATOM   7575 N N   . ASN D 4 496 ? 154.637 149.282 175.539 1.00 92.77  ? 360 ASN R N   1 
ATOM   7576 C CA  . ASN D 4 496 ? 153.643 148.543 174.760 1.00 89.44  ? 360 ASN R CA  1 
ATOM   7577 C C   . ASN D 4 496 ? 153.775 148.754 173.255 1.00 91.06  ? 360 ASN R C   1 
ATOM   7578 O O   . ASN D 4 496 ? 153.692 147.762 172.509 1.00 95.04  ? 360 ASN R O   1 
ATOM   7579 C CB  . ASN D 4 496 ? 152.236 148.898 175.251 1.00 91.48  ? 360 ASN R CB  1 
ATOM   7580 N N   . PRO D 4 497 ? 153.939 149.980 172.734 1.00 88.91  ? 361 PRO R N   1 
ATOM   7581 C CA  . PRO D 4 497 ? 154.120 150.117 171.276 1.00 90.12  ? 361 PRO R CA  1 
ATOM   7582 C C   . PRO D 4 497 ? 155.346 149.394 170.744 1.00 89.92  ? 361 PRO R C   1 
ATOM   7583 O O   . PRO D 4 497 ? 155.308 148.854 169.631 1.00 91.32  ? 361 PRO R O   1 
ATOM   7584 C CB  . PRO D 4 497 ? 154.230 151.636 171.080 1.00 90.84  ? 361 PRO R CB  1 
ATOM   7585 C CG  . PRO D 4 497 ? 153.559 152.220 172.263 1.00 91.78  ? 361 PRO R CG  1 
ATOM   7586 C CD  . PRO D 4 497 ? 153.859 151.295 173.393 1.00 89.46  ? 361 PRO R CD  1 
ATOM   7587 N N   . ILE D 4 498 ? 156.436 149.369 171.513 1.00 86.57  ? 362 ILE R N   1 
ATOM   7588 C CA  . ILE D 4 498 ? 157.629 148.640 171.091 1.00 89.15  ? 362 ILE R CA  1 
ATOM   7589 C C   . ILE D 4 498 ? 157.322 147.155 170.966 1.00 90.38  ? 362 ILE R C   1 
ATOM   7590 O O   . ILE D 4 498 ? 157.735 146.495 170.004 1.00 90.60  ? 362 ILE R O   1 
ATOM   7591 C CB  . ILE D 4 498 ? 158.787 148.899 172.072 1.00 89.28  ? 362 ILE R CB  1 
ATOM   7592 C CG1 . ILE D 4 498 ? 159.107 150.392 172.141 1.00 88.63  ? 362 ILE R CG1 1 
ATOM   7593 C CG2 . ILE D 4 498 ? 160.018 148.098 171.676 1.00 89.97  ? 362 ILE R CG2 1 
ATOM   7594 C CD1 . ILE D 4 498 ? 160.273 150.720 173.045 1.00 88.78  ? 362 ILE R CD1 1 
ATOM   7595 N N   . LEU D 4 499 ? 156.592 146.609 171.938 1.00 90.89  ? 363 LEU R N   1 
ATOM   7596 C CA  . LEU D 4 499 ? 156.205 145.205 171.883 1.00 90.04  ? 363 LEU R CA  1 
ATOM   7597 C C   . LEU D 4 499 ? 155.299 144.934 170.688 1.00 89.84  ? 363 LEU R C   1 
ATOM   7598 O O   . LEU D 4 499 ? 155.441 143.904 170.017 1.00 92.00  ? 363 LEU R O   1 
ATOM   7599 C CB  . LEU D 4 499 ? 155.526 144.818 173.198 1.00 91.11  ? 363 LEU R CB  1 
ATOM   7600 C CG  . LEU D 4 499 ? 155.231 143.368 173.588 1.00 91.03  ? 363 LEU R CG  1 
ATOM   7601 C CD1 . LEU D 4 499 ? 154.941 143.332 175.073 1.00 92.46  ? 363 LEU R CD1 1 
ATOM   7602 C CD2 . LEU D 4 499 ? 154.059 142.779 172.821 1.00 89.22  ? 363 LEU R CD2 1 
ATOM   7603 N N   . TYR D 4 500 ? 154.361 145.842 170.408 1.00 94.33  ? 364 TYR R N   1 
ATOM   7604 C CA  . TYR D 4 500 ? 153.485 145.664 169.253 1.00 93.63  ? 364 TYR R CA  1 
ATOM   7605 C C   . TYR D 4 500 ? 154.283 145.651 167.958 1.00 95.82  ? 364 TYR R C   1 
ATOM   7606 O O   . TYR D 4 500 ? 154.017 144.841 167.062 1.00 96.73  ? 364 TYR R O   1 
ATOM   7607 C CB  . TYR D 4 500 ? 152.430 146.768 169.209 1.00 93.88  ? 364 TYR R CB  1 
ATOM   7608 C CG  . TYR D 4 500 ? 151.438 146.716 170.342 1.00 95.16  ? 364 TYR R CG  1 
ATOM   7609 C CD1 . TYR D 4 500 ? 151.175 145.528 171.005 1.00 96.34  ? 364 TYR R CD1 1 
ATOM   7610 C CD2 . TYR D 4 500 ? 150.765 147.858 170.751 1.00 94.97  ? 364 TYR R CD2 1 
ATOM   7611 C CE1 . TYR D 4 500 ? 150.270 145.478 172.042 1.00 96.75  ? 364 TYR R CE1 1 
ATOM   7612 C CE2 . TYR D 4 500 ? 149.857 147.817 171.787 1.00 95.78  ? 364 TYR R CE2 1 
ATOM   7613 C CZ  . TYR D 4 500 ? 149.614 146.624 172.429 1.00 95.88  ? 364 TYR R CZ  1 
ATOM   7614 O OH  . TYR D 4 500 ? 148.711 146.575 173.462 1.00 96.32  ? 364 TYR R OH  1 
ATOM   7615 N N   . ASN D 4 501 ? 155.258 146.554 167.836 1.00 99.90  ? 365 ASN R N   1 
ATOM   7616 C CA  . ASN D 4 501 ? 156.101 146.575 166.645 1.00 98.85  ? 365 ASN R CA  1 
ATOM   7617 C C   . ASN D 4 501 ? 156.913 145.292 166.524 1.00 99.15  ? 365 ASN R C   1 
ATOM   7618 O O   . ASN D 4 501 ? 157.043 144.732 165.430 1.00 101.39 ? 365 ASN R O   1 
ATOM   7619 C CB  . ASN D 4 501 ? 157.011 147.807 166.675 1.00 97.91  ? 365 ASN R CB  1 
ATOM   7620 C CG  . ASN D 4 501 ? 158.296 147.617 165.884 1.00 98.68  ? 365 ASN R CG  1 
ATOM   7621 O OD1 . ASN D 4 501 ? 159.218 146.924 166.319 1.00 99.17  ? 365 ASN R OD1 1 
ATOM   7622 N ND2 . ASN D 4 501 ? 158.361 148.238 164.714 1.00 99.25  ? 365 ASN R ND2 1 
ATOM   7623 N N   . LEU D 4 502 ? 157.468 144.810 167.639 1.00 95.29  ? 366 LEU R N   1 
ATOM   7624 C CA  . LEU D 4 502 ? 158.324 143.628 167.587 1.00 96.06  ? 366 LEU R CA  1 
ATOM   7625 C C   . LEU D 4 502 ? 157.535 142.370 167.241 1.00 95.56  ? 366 LEU R C   1 
ATOM   7626 O O   . LEU D 4 502 ? 157.990 141.549 166.436 1.00 95.35  ? 366 LEU R O   1 
ATOM   7627 C CB  . LEU D 4 502 ? 159.054 143.448 168.918 1.00 96.06  ? 366 LEU R CB  1 
ATOM   7628 C CG  . LEU D 4 502 ? 160.441 144.084 169.047 1.00 96.88  ? 366 LEU R CG  1 
ATOM   7629 C CD1 . LEU D 4 502 ? 161.226 143.429 170.172 1.00 96.18  ? 366 LEU R CD1 1 
ATOM   7630 C CD2 . LEU D 4 502 ? 161.208 143.997 167.737 1.00 96.32  ? 366 LEU R CD2 1 
ATOM   7631 N N   . VAL D 4 503 ? 156.355 142.195 167.840 1.00 93.19  ? 367 VAL R N   1 
ATOM   7632 C CA  . VAL D 4 503 ? 155.620 140.942 167.683 1.00 90.82  ? 367 VAL R CA  1 
ATOM   7633 C C   . VAL D 4 503 ? 155.113 140.786 166.254 1.00 92.18  ? 367 VAL R C   1 
ATOM   7634 O O   . VAL D 4 503 ? 155.281 139.731 165.631 1.00 94.08  ? 367 VAL R O   1 
ATOM   7635 C CB  . VAL D 4 503 ? 154.464 140.869 168.697 1.00 91.67  ? 367 VAL R CB  1 
ATOM   7636 C CG1 . VAL D 4 503 ? 153.396 139.896 168.222 1.00 89.89  ? 367 VAL R CG1 1 
ATOM   7637 C CG2 . VAL D 4 503 ? 154.984 140.470 170.064 1.00 92.72  ? 367 VAL R CG2 1 
ATOM   7638 N N   . SER D 4 504 ? 154.494 141.827 165.713 1.00 95.26  ? 368 SER R N   1 
ATOM   7639 C CA  . SER D 4 504 ? 153.826 141.724 164.426 1.00 96.95  ? 368 SER R CA  1 
ATOM   7640 C C   . SER D 4 504 ? 154.751 142.158 163.295 1.00 99.25  ? 368 SER R C   1 
ATOM   7641 O O   . SER D 4 504 ? 155.791 142.783 163.512 1.00 99.32  ? 368 SER R O   1 
ATOM   7642 C CB  . SER D 4 504 ? 152.551 142.566 164.413 1.00 95.98  ? 368 SER R CB  1 
ATOM   7643 N N   . ALA D 4 505 ? 154.351 141.812 162.072 1.00 98.50  ? 369 ALA R N   1 
ATOM   7644 C CA  . ALA D 4 505 ? 155.097 142.150 160.867 1.00 96.47  ? 369 ALA R CA  1 
ATOM   7645 C C   . ALA D 4 505 ? 154.365 143.147 159.983 1.00 96.81  ? 369 ALA R C   1 
ATOM   7646 O O   . ALA D 4 505 ? 154.918 144.199 159.647 1.00 96.53  ? 369 ALA R O   1 
ATOM   7647 C CB  . ALA D 4 505 ? 155.408 140.878 160.066 1.00 96.10  ? 369 ALA R CB  1 
ATOM   7648 N N   . ASN D 4 506 ? 153.125 142.841 159.594 1.00 96.05  ? 370 ASN R N   1 
ATOM   7649 C CA  . ASN D 4 506 ? 152.346 143.784 158.799 1.00 94.48  ? 370 ASN R CA  1 
ATOM   7650 C C   . ASN D 4 506 ? 152.070 145.059 159.583 1.00 94.56  ? 370 ASN R C   1 
ATOM   7651 O O   . ASN D 4 506 ? 152.061 146.158 159.017 1.00 93.49  ? 370 ASN R O   1 
ATOM   7652 C CB  . ASN D 4 506 ? 151.040 143.134 158.348 1.00 91.82  ? 370 ASN R CB  1 
ATOM   7653 C CG  . ASN D 4 506 ? 151.157 141.632 158.213 1.00 93.77  ? 370 ASN R CG  1 
ATOM   7654 O OD1 . ASN D 4 506 ? 150.799 140.886 159.123 1.00 95.38  ? 370 ASN R OD1 1 
ATOM   7655 N ND2 . ASN D 4 506 ? 151.665 141.179 157.074 1.00 93.04  ? 370 ASN R ND2 1 
ATOM   7656 N N   . PHE D 4 507 ? 151.830 144.926 160.890 1.00 103.08 ? 371 PHE R N   1 
ATOM   7657 C CA  . PHE D 4 507 ? 151.701 146.099 161.747 1.00 104.49 ? 371 PHE R CA  1 
ATOM   7658 C C   . PHE D 4 507 ? 153.004 146.886 161.805 1.00 103.83 ? 371 PHE R C   1 
ATOM   7659 O O   . PHE D 4 507 ? 152.992 148.122 161.784 1.00 102.25 ? 371 PHE R O   1 
ATOM   7660 C CB  . PHE D 4 507 ? 151.271 145.671 163.150 1.00 103.42 ? 371 PHE R CB  1 
ATOM   7661 C CG  . PHE D 4 507 ? 150.845 146.809 164.032 1.00 103.15 ? 371 PHE R CG  1 
ATOM   7662 C CD1 . PHE D 4 507 ? 151.776 147.514 164.777 1.00 103.20 ? 371 PHE R CD1 1 
ATOM   7663 C CD2 . PHE D 4 507 ? 149.510 147.166 164.126 1.00 102.56 ? 371 PHE R CD2 1 
ATOM   7664 C CE1 . PHE D 4 507 ? 151.385 148.559 165.589 1.00 103.22 ? 371 PHE R CE1 1 
ATOM   7665 C CE2 . PHE D 4 507 ? 149.114 148.207 164.941 1.00 103.62 ? 371 PHE R CE2 1 
ATOM   7666 C CZ  . PHE D 4 507 ? 150.052 148.905 165.671 1.00 103.68 ? 371 PHE R CZ  1 
ATOM   7667 N N   . ARG D 4 508 ? 154.140 146.186 161.888 1.00 99.87  ? 372 ARG R N   1 
ATOM   7668 C CA  . ARG D 4 508 ? 155.424 146.871 162.003 1.00 99.69  ? 372 ARG R CA  1 
ATOM   7669 C C   . ARG D 4 508 ? 155.724 147.695 160.757 1.00 101.19 ? 372 ARG R C   1 
ATOM   7670 O O   . ARG D 4 508 ? 156.261 148.805 160.854 1.00 100.80 ? 372 ARG R O   1 
ATOM   7671 C CB  . ARG D 4 508 ? 156.544 145.861 162.264 1.00 99.79  ? 372 ARG R CB  1 
ATOM   7672 C CG  . ARG D 4 508 ? 157.937 146.413 161.971 1.00 100.33 ? 372 ARG R CG  1 
ATOM   7673 C CD  . ARG D 4 508 ? 159.115 145.497 162.352 1.00 99.40  ? 372 ARG R CD  1 
ATOM   7674 N NE  . ARG D 4 508 ? 158.788 144.115 162.691 1.00 100.05 ? 372 ARG R NE  1 
ATOM   7675 C CZ  . ARG D 4 508 ? 158.314 143.213 161.841 1.00 99.97  ? 372 ARG R CZ  1 
ATOM   7676 N NH1 . ARG D 4 508 ? 158.101 143.506 160.568 1.00 100.15 ? 372 ARG R NH1 1 
ATOM   7677 N NH2 . ARG D 4 508 ? 158.063 141.981 162.275 1.00 99.34  ? 372 ARG R NH2 1 
ATOM   7678 N N   . HIS D 4 509 ? 155.381 147.170 159.579 1.00 102.30 ? 373 HIS R N   1 
ATOM   7679 C CA  . HIS D 4 509 ? 155.621 147.907 158.343 1.00 102.91 ? 373 HIS R CA  1 
ATOM   7680 C C   . HIS D 4 509 ? 154.836 149.212 158.314 1.00 104.21 ? 373 HIS R C   1 
ATOM   7681 O O   . HIS D 4 509 ? 155.372 150.261 157.938 1.00 105.48 ? 373 HIS R O   1 
ATOM   7682 C CB  . HIS D 4 509 ? 155.261 147.036 157.140 1.00 102.13 ? 373 HIS R CB  1 
ATOM   7683 C CG  . HIS D 4 509 ? 155.743 147.582 155.833 1.00 102.94 ? 373 HIS R CG  1 
ATOM   7684 N ND1 . HIS D 4 509 ? 155.100 147.333 154.641 1.00 104.55 ? 373 HIS R ND1 1 
ATOM   7685 C CD2 . HIS D 4 509 ? 156.804 148.367 155.532 1.00 102.49 ? 373 HIS R CD2 1 
ATOM   7686 C CE1 . HIS D 4 509 ? 155.745 147.939 153.660 1.00 104.55 ? 373 HIS R CE1 1 
ATOM   7687 N NE2 . HIS D 4 509 ? 156.783 148.574 154.174 1.00 104.68 ? 373 HIS R NE2 1 
ATOM   7688 N N   . ILE D 4 510 ? 153.563 149.170 158.713 1.00 98.62  ? 374 ILE R N   1 
ATOM   7689 C CA  . ILE D 4 510 ? 152.746 150.379 158.712 1.00 97.89  ? 374 ILE R CA  1 
ATOM   7690 C C   . ILE D 4 510 ? 153.197 151.337 159.808 1.00 97.67  ? 374 ILE R C   1 
ATOM   7691 O O   . ILE D 4 510 ? 153.293 152.551 159.590 1.00 96.44  ? 374 ILE R O   1 
ATOM   7692 C CB  . ILE D 4 510 ? 151.258 150.013 158.852 1.00 96.91  ? 374 ILE R CB  1 
ATOM   7693 C CG1 . ILE D 4 510 ? 150.852 149.021 157.756 1.00 97.01  ? 374 ILE R CG1 1 
ATOM   7694 C CG2 . ILE D 4 510 ? 150.396 151.264 158.807 1.00 96.45  ? 374 ILE R CG2 1 
ATOM   7695 C CD1 . ILE D 4 510 ? 149.385 149.060 157.388 1.00 96.43  ? 374 ILE R CD1 1 
ATOM   7696 N N   . PHE D 4 511 ? 153.479 150.811 161.002 1.00 103.98 ? 375 PHE R N   1 
ATOM   7697 C CA  . PHE D 4 511 ? 153.848 151.665 162.127 1.00 104.51 ? 375 PHE R CA  1 
ATOM   7698 C C   . PHE D 4 511 ? 155.168 152.381 161.871 1.00 104.60 ? 375 PHE R C   1 
ATOM   7699 O O   . PHE D 4 511 ? 155.304 153.576 162.153 1.00 105.55 ? 375 PHE R O   1 
ATOM   7700 C CB  . PHE D 4 511 ? 153.917 150.832 163.410 1.00 105.68 ? 375 PHE R CB  1 
ATOM   7701 C CG  . PHE D 4 511 ? 154.882 151.364 164.435 1.00 105.71 ? 375 PHE R CG  1 
ATOM   7702 C CD1 . PHE D 4 511 ? 154.524 152.411 165.266 1.00 102.98 ? 375 PHE R CD1 1 
ATOM   7703 C CD2 . PHE D 4 511 ? 156.137 150.798 164.585 1.00 106.55 ? 375 PHE R CD2 1 
ATOM   7704 C CE1 . PHE D 4 511 ? 155.408 152.894 166.212 1.00 102.39 ? 375 PHE R CE1 1 
ATOM   7705 C CE2 . PHE D 4 511 ? 157.022 151.278 165.530 1.00 105.12 ? 375 PHE R CE2 1 
ATOM   7706 C CZ  . PHE D 4 511 ? 156.657 152.326 166.344 1.00 102.49 ? 375 PHE R CZ  1 
ATOM   7707 N N   . ILE D 4 512 ? 156.157 151.665 161.334 1.00 105.16 ? 376 ILE R N   1 
ATOM   7708 C CA  . ILE D 4 512 ? 157.473 152.262 161.123 1.00 105.78 ? 376 ILE R CA  1 
ATOM   7709 C C   . ILE D 4 512 ? 157.417 153.326 160.034 1.00 107.11 ? 376 ILE R C   1 
ATOM   7710 O O   . ILE D 4 512 ? 158.073 154.370 160.135 1.00 108.12 ? 376 ILE R O   1 
ATOM   7711 C CB  . ILE D 4 512 ? 158.508 151.168 160.801 1.00 105.84 ? 376 ILE R CB  1 
ATOM   7712 C CG1 . ILE D 4 512 ? 158.891 150.408 162.071 1.00 105.61 ? 376 ILE R CG1 1 
ATOM   7713 C CG2 . ILE D 4 512 ? 159.740 151.761 160.142 1.00 107.10 ? 376 ILE R CG2 1 
ATOM   7714 C CD1 . ILE D 4 512 ? 159.961 149.365 161.855 1.00 106.53 ? 376 ILE R CD1 1 
ATOM   7715 N N   . ALA D 4 513 ? 156.621 153.091 158.988 1.00 108.29 ? 377 ALA R N   1 
ATOM   7716 C CA  . ALA D 4 513 ? 156.633 153.979 157.829 1.00 108.92 ? 377 ALA R CA  1 
ATOM   7717 C C   . ALA D 4 513 ? 156.229 155.401 158.202 1.00 108.65 ? 377 ALA R C   1 
ATOM   7718 O O   . ALA D 4 513 ? 156.863 156.368 157.764 1.00 106.70 ? 377 ALA R O   1 
ATOM   7719 C CB  . ALA D 4 513 ? 155.713 153.429 156.740 1.00 107.66 ? 377 ALA R CB  1 
ATOM   7720 N N   . THR D 4 514 ? 155.185 155.550 159.013 1.00 111.45 ? 378 THR R N   1 
ATOM   7721 C CA  . THR D 4 514 ? 154.695 156.865 159.403 1.00 111.82 ? 378 THR R CA  1 
ATOM   7722 C C   . THR D 4 514 ? 155.243 157.336 160.744 1.00 110.71 ? 378 THR R C   1 
ATOM   7723 O O   . THR D 4 514 ? 154.839 158.399 161.223 1.00 110.82 ? 378 THR R O   1 
ATOM   7724 C CB  . THR D 4 514 ? 153.165 156.872 159.438 1.00 111.17 ? 378 THR R CB  1 
ATOM   7725 O OG1 . THR D 4 514 ? 152.688 155.615 159.936 1.00 108.73 ? 378 THR R OG1 1 
ATOM   7726 C CG2 . THR D 4 514 ? 152.611 157.112 158.042 1.00 110.74 ? 378 THR R CG2 1 
ATOM   7727 N N   . LEU D 4 515 ? 156.147 156.576 161.359 1.00 110.53 ? 379 LEU R N   1 
ATOM   7728 C CA  . LEU D 4 515 ? 156.801 156.993 162.589 1.00 109.47 ? 379 LEU R CA  1 
ATOM   7729 C C   . LEU D 4 515 ? 158.316 157.053 162.479 1.00 110.05 ? 379 LEU R C   1 
ATOM   7730 O O   . LEU D 4 515 ? 158.963 157.557 163.404 1.00 110.17 ? 379 LEU R O   1 
ATOM   7731 C CB  . LEU D 4 515 ? 156.421 156.057 163.747 1.00 109.82 ? 379 LEU R CB  1 
ATOM   7732 N N   . ALA D 4 516 ? 158.898 156.553 161.394 1.00 108.90 ? 380 ALA R N   1 
ATOM   7733 C CA  . ALA D 4 516 ? 160.343 156.578 161.214 1.00 108.31 ? 380 ALA R CA  1 
ATOM   7734 C C   . ALA D 4 516 ? 160.702 156.559 159.732 1.00 107.80 ? 380 ALA R C   1 
ATOM   7735 O O   . ALA D 4 516 ? 161.878 156.560 159.367 1.00 107.79 ? 380 ALA R O   1 
ATOM   7736 C CB  . ALA D 4 516 ? 160.988 155.406 161.933 1.00 107.11 ? 380 ALA R CB  1 
ATOM   7737 N N   . ASN D 4 544 ? 160.556 122.494 133.829 1.00 43.97  ? 405 ASN R N   1 
ATOM   7738 C CA  . ASN D 4 544 ? 160.436 123.041 132.485 1.00 47.83  ? 405 ASN R CA  1 
ATOM   7739 C C   . ASN D 4 544 ? 159.343 124.099 132.421 1.00 52.16  ? 405 ASN R C   1 
ATOM   7740 O O   . ASN D 4 544 ? 158.618 124.317 133.391 1.00 51.85  ? 405 ASN R O   1 
ATOM   7741 C CB  . ASN D 4 544 ? 160.146 121.930 131.476 1.00 43.45  ? 405 ASN R CB  1 
ATOM   7742 C CG  . ASN D 4 544 ? 161.312 120.984 131.302 1.00 46.44  ? 405 ASN R CG  1 
ATOM   7743 O OD1 . ASN D 4 544 ? 162.294 121.049 132.039 1.00 49.30  ? 405 ASN R OD1 1 
ATOM   7744 N ND2 . ASN D 4 544 ? 161.211 120.096 130.321 1.00 45.82  ? 405 ASN R ND2 1 
ATOM   7745 N N   . HIS D 4 545 ? 159.229 124.753 131.272 1.00 53.33  ? 406 HIS R N   1 
ATOM   7746 C CA  . HIS D 4 545 ? 158.180 125.738 131.060 1.00 50.85  ? 406 HIS R CA  1 
ATOM   7747 C C   . HIS D 4 545 ? 157.037 125.117 130.269 1.00 50.68  ? 406 HIS R C   1 
ATOM   7748 O O   . HIS D 4 545 ? 157.224 124.117 129.578 1.00 50.73  ? 406 HIS R O   1 
ATOM   7749 C CB  . HIS D 4 545 ? 158.727 126.964 130.328 1.00 45.88  ? 406 HIS R CB  1 
ATOM   7750 C CG  . HIS D 4 545 ? 159.782 127.703 131.091 1.00 52.87  ? 406 HIS R CG  1 
ATOM   7751 N ND1 . HIS D 4 545 ? 159.500 128.467 132.202 1.00 57.63  ? 406 HIS R ND1 1 
ATOM   7752 C CD2 . HIS D 4 545 ? 161.119 127.796 130.899 1.00 54.72  ? 406 HIS R CD2 1 
ATOM   7753 C CE1 . HIS D 4 545 ? 160.618 128.997 132.664 1.00 54.64  ? 406 HIS R CE1 1 
ATOM   7754 N NE2 . HIS D 4 545 ? 161.615 128.606 131.891 1.00 56.22  ? 406 HIS R NE2 1 
HETATM 7755 N N   . TPO D 4 546 ? 155.854 125.708 130.380 1.00 2084.4 ? 407 TPO R N   1 
HETATM 7756 C CA  . TPO D 4 546 ? 154.703 125.263 129.610 1.00 2117.6 ? 407 TPO R CA  1 
HETATM 7757 C CB  . TPO D 4 546 ? 153.413 125.761 130.237 1.00 2165.4 ? 407 TPO R CB  1 
HETATM 7758 C CG2 . TPO D 4 546 ? 152.231 125.315 129.377 1.00 2106.4 ? 407 TPO R CG2 1 
HETATM 7759 O OG1 . TPO D 4 546 ? 153.256 125.229 131.550 1.00 2120.7 ? 407 TPO R OG1 1 
HETATM 7760 P P   . TPO D 4 546 ? 153.580 126.401 132.602 1.00 2197.4 ? 407 TPO R P   1 
HETATM 7761 O O1P . TPO D 4 546 ? 154.564 127.343 132.029 1.00 2259.1 ? 407 TPO R O1P 1 
HETATM 7762 O O2P . TPO D 4 546 ? 152.231 127.203 132.944 1.00 2149.8 ? 407 TPO R O2P 1 
HETATM 7763 O O3P . TPO D 4 546 ? 154.176 125.757 133.948 1.00 2202.5 ? 407 TPO R O3P 1 
HETATM 7764 C C   . TPO D 4 546 ? 154.820 125.752 128.175 1.00 2182.3 ? 407 TPO R C   1 
HETATM 7765 O O   . TPO D 4 546 ? 154.782 126.953 127.916 1.00 2218.1 ? 407 TPO R O   1 
ATOM   7766 N N   . LEU D 4 547 ? 154.968 124.820 127.243 1.00 2098.5 ? 408 LEU R N   1 
ATOM   7767 C CA  . LEU D 4 547 ? 155.084 125.173 125.837 1.00 2080.2 ? 408 LEU R CA  1 
ATOM   7768 C C   . LEU D 4 547 ? 153.721 125.142 125.171 1.00 2117.7 ? 408 LEU R C   1 
ATOM   7769 O O   . LEU D 4 547 ? 152.698 125.025 125.837 1.00 2094.4 ? 408 LEU R O   1 
ATOM   7770 C CB  . LEU D 4 547 ? 156.042 124.224 125.118 1.00 37.65  ? 408 LEU R CB  1 
ATOM   7771 C CG  . LEU D 4 547 ? 157.421 124.026 125.746 1.00 34.52  ? 408 LEU R CG  1 
ATOM   7772 C CD1 . LEU D 4 547 ? 158.200 122.973 124.985 1.00 35.56  ? 408 LEU R CD1 1 
ATOM   7773 C CD2 . LEU D 4 547 ? 158.190 125.334 125.785 1.00 32.63  ? 408 LEU R CD2 1 
HETATM 7774 N N   . SEP D 4 548 ? 153.715 125.248 123.850 1.00 2197.7 ? 409 SEP R N   1 
HETATM 7775 C CA  . SEP D 4 548 ? 152.481 125.176 123.084 1.00 2185.1 ? 409 SEP R CA  1 
HETATM 7776 C CB  . SEP D 4 548 ? 151.943 126.573 122.780 1.00 2255.3 ? 409 SEP R CB  1 
HETATM 7777 O OG  . SEP D 4 548 ? 152.813 127.257 121.894 1.00 2270.0 ? 409 SEP R OG  1 
HETATM 7778 C C   . SEP D 4 548 ? 152.721 124.420 121.791 1.00 2184.4 ? 409 SEP R C   1 
HETATM 7779 O O   . SEP D 4 548 ? 153.807 124.476 121.219 1.00 2217.4 ? 409 SEP R O   1 
HETATM 7780 P P   . SEP D 4 548 ? 152.155 128.623 121.367 1.00 2055.2 ? 409 SEP R P   1 
HETATM 7781 O O1P . SEP D 4 548 ? 150.552 128.515 121.365 1.00 2091.7 ? 409 SEP R O1P 1 
HETATM 7782 O O2P . SEP D 4 548 ? 152.610 129.825 122.329 1.00 2206.6 ? 409 SEP R O2P 1 
HETATM 7783 O O3P . SEP D 4 548 ? 152.673 128.915 119.877 1.00 2032.9 ? 409 SEP R O3P 1 
HETATM 7784 N N   . SEP D 4 549 ? 151.700 123.709 121.335 1.00 2136.5 ? 410 SEP R N   1 
HETATM 7785 C CA  . SEP D 4 549 ? 151.766 122.998 120.072 1.00 2085.0 ? 410 SEP R CA  1 
HETATM 7786 C CB  . SEP D 4 549 ? 152.548 121.694 120.217 1.00 2144.4 ? 410 SEP R CB  1 
HETATM 7787 O OG  . SEP D 4 549 ? 152.686 121.047 118.967 1.00 2161.5 ? 410 SEP R OG  1 
HETATM 7788 C C   . SEP D 4 549 ? 150.353 122.731 119.587 1.00 1936.8 ? 410 SEP R C   1 
HETATM 7789 O O   . SEP D 4 549 ? 149.389 123.095 120.253 1.00 1920.9 ? 410 SEP R O   1 
HETATM 7790 P P   . SEP D 4 549 ? 153.975 120.086 118.971 1.00 2185.2 ? 410 SEP R P   1 
HETATM 7791 O O1P . SEP D 4 549 ? 155.255 120.910 119.489 1.00 2225.6 ? 410 SEP R O1P 1 
HETATM 7792 O O2P . SEP D 4 549 ? 154.235 119.556 117.476 1.00 2212.2 ? 410 SEP R O2P 1 
HETATM 7793 O O3P . SEP D 4 549 ? 153.732 118.832 119.947 1.00 2155.0 ? 410 SEP R O3P 1 
ATOM   7794 N N   . ASN D 4 550 ? 150.228 122.100 118.427 1.00 43.53  ? 411 ASN R N   1 
ATOM   7795 C CA  . ASN D 4 550 ? 148.916 121.782 117.882 1.00 37.93  ? 411 ASN R CA  1 
ATOM   7796 C C   . ASN D 4 550 ? 148.820 120.304 117.536 1.00 40.90  ? 411 ASN R C   1 
ATOM   7797 O O   . ASN D 4 550 ? 149.801 119.690 117.125 1.00 44.30  ? 411 ASN R O   1 
ATOM   7798 C CB  . ASN D 4 550 ? 148.626 122.638 116.649 1.00 33.58  ? 411 ASN R CB  1 
ATOM   7799 C CG  . ASN D 4 550 ? 149.820 122.752 115.725 1.00 39.23  ? 411 ASN R CG  1 
ATOM   7800 O OD1 . ASN D 4 550 ? 150.967 122.781 116.171 1.00 41.78  ? 411 ASN R OD1 1 
ATOM   7801 N ND2 . ASN D 4 550 ? 149.555 122.816 114.427 1.00 41.24  ? 411 ASN R ND2 1 
ATOM   7802 N N   . ALA D 4 551 ? 147.635 119.734 117.710 1.00 42.54  ? 412 ALA R N   1 
ATOM   7803 C CA  . ALA D 4 551 ? 147.417 118.322 117.422 1.00 43.36  ? 412 ALA R CA  1 
ATOM   7804 C C   . ALA D 4 551 ? 147.496 118.049 115.923 1.00 48.79  ? 412 ALA R C   1 
ATOM   7805 O O   . ALA D 4 551 ? 146.490 118.108 115.217 1.00 51.93  ? 412 ALA R O   1 
ATOM   7806 C CB  . ALA D 4 551 ? 146.077 117.871 117.972 1.00 45.72  ? 412 ALA R CB  1 
ATOM   7807 N N   . ARG E 5 1   ? 157.971 159.874 209.717 1.00 127.53 ? 8   ARG L N   1 
ATOM   7808 C CA  . ARG E 5 1   ? 157.098 159.604 208.581 1.00 127.75 ? 8   ARG L CA  1 
ATOM   7809 C C   . ARG E 5 1   ? 156.747 160.895 207.850 1.00 127.31 ? 8   ARG L C   1 
ATOM   7810 O O   . ARG E 5 1   ? 155.938 161.688 208.329 1.00 127.09 ? 8   ARG L O   1 
ATOM   7811 C CB  . ARG E 5 1   ? 155.823 158.894 209.040 1.00 128.18 ? 8   ARG L CB  1 
ATOM   7812 C CG  . ARG E 5 1   ? 155.007 158.288 207.912 1.00 127.88 ? 8   ARG L CG  1 
ATOM   7813 C CD  . ARG E 5 1   ? 153.746 157.628 208.443 1.00 127.46 ? 8   ARG L CD  1 
ATOM   7814 N NE  . ARG E 5 1   ? 152.775 158.609 208.910 1.00 127.42 ? 8   ARG L NE  1 
ATOM   7815 C CZ  . ARG E 5 1   ? 151.879 159.203 208.134 1.00 127.11 ? 8   ARG L CZ  1 
ATOM   7816 N NH1 . ARG E 5 1   ? 151.795 158.931 206.842 1.00 125.94 ? 8   ARG L NH1 1 
ATOM   7817 N NH2 . ARG E 5 1   ? 151.045 160.091 208.669 1.00 127.24 ? 8   ARG L NH2 1 
ATOM   7818 N N   . ARG E 5 2   ? 157.362 161.101 206.683 1.00 129.40 ? 9   ARG L N   1 
ATOM   7819 C CA  . ARG E 5 2   ? 157.134 162.306 205.882 1.00 129.88 ? 9   ARG L CA  1 
ATOM   7820 C C   . ARG E 5 2   ? 156.888 161.965 204.413 1.00 130.01 ? 9   ARG L C   1 
ATOM   7821 O O   . ARG E 5 2   ? 157.526 162.522 203.520 1.00 131.15 ? 9   ARG L O   1 
ATOM   7822 C CB  . ARG E 5 2   ? 158.325 163.248 206.022 1.00 129.92 ? 9   ARG L CB  1 
ATOM   7823 C CG  . ARG E 5 2   ? 159.665 162.521 206.038 1.00 129.54 ? 9   ARG L CG  1 
ATOM   7824 C CD  . ARG E 5 2   ? 160.733 163.246 205.225 1.00 129.00 ? 9   ARG L CD  1 
ATOM   7825 N NE  . ARG E 5 2   ? 160.432 163.312 203.798 1.00 130.66 ? 9   ARG L NE  1 
ATOM   7826 C CZ  . ARG E 5 2   ? 160.406 162.271 202.975 1.00 130.18 ? 9   ARG L CZ  1 
ATOM   7827 N NH1 . ARG E 5 2   ? 160.638 161.042 203.404 1.00 129.01 ? 9   ARG L NH1 1 
ATOM   7828 N NH2 . ARG E 5 2   ? 160.132 162.468 201.688 1.00 128.98 ? 9   ARG L NH2 1 
ATOM   7829 N N   . PRO E 5 3   ? 155.947 161.056 204.118 1.00 129.56 ? 10  PRO L N   1 
ATOM   7830 C CA  . PRO E 5 3   ? 155.796 160.608 202.729 1.00 130.43 ? 10  PRO L CA  1 
ATOM   7831 C C   . PRO E 5 3   ? 154.814 161.439 201.916 1.00 130.56 ? 10  PRO L C   1 
ATOM   7832 O O   . PRO E 5 3   ? 154.868 161.427 200.681 1.00 129.22 ? 10  PRO L O   1 
ATOM   7833 C CB  . PRO E 5 3   ? 155.299 159.168 202.896 1.00 130.02 ? 10  PRO L CB  1 
ATOM   7834 C CG  . PRO E 5 3   ? 154.512 159.196 204.192 1.00 128.87 ? 10  PRO L CG  1 
ATOM   7835 C CD  . PRO E 5 3   ? 154.950 160.411 204.993 1.00 128.91 ? 10  PRO L CD  1 
ATOM   7836 N N   . TYR E 5 4   ? 153.919 162.163 202.593 1.00 129.01 ? 11  TYR L N   1 
ATOM   7837 C CA  . TYR E 5 4   ? 152.772 162.810 201.949 1.00 128.46 ? 11  TYR L CA  1 
ATOM   7838 C C   . TYR E 5 4   ? 151.968 161.810 201.120 1.00 128.07 ? 11  TYR L C   1 
ATOM   7839 O O   . TYR E 5 4   ? 151.289 162.183 200.161 1.00 127.90 ? 11  TYR L O   1 
ATOM   7840 C CB  . TYR E 5 4   ? 153.204 164.000 201.087 1.00 128.39 ? 11  TYR L CB  1 
ATOM   7841 C CG  . TYR E 5 4   ? 154.139 164.965 201.780 1.00 128.15 ? 11  TYR L CG  1 
ATOM   7842 C CD1 . TYR E 5 4   ? 153.675 165.823 202.767 1.00 128.00 ? 11  TYR L CD1 1 
ATOM   7843 C CD2 . TYR E 5 4   ? 155.483 165.025 201.439 1.00 128.38 ? 11  TYR L CD2 1 
ATOM   7844 C CE1 . TYR E 5 4   ? 154.526 166.709 203.400 1.00 128.87 ? 11  TYR L CE1 1 
ATOM   7845 C CE2 . TYR E 5 4   ? 156.341 165.907 202.065 1.00 128.45 ? 11  TYR L CE2 1 
ATOM   7846 C CZ  . TYR E 5 4   ? 155.858 166.747 203.045 1.00 128.82 ? 11  TYR L CZ  1 
ATOM   7847 O OH  . TYR E 5 4   ? 156.711 167.628 203.670 1.00 127.07 ? 11  TYR L OH  1 
ATOM   7848 N N   . ILE E 5 5   ? 152.042 160.532 201.501 1.00 125.23 ? 12  ILE L N   1 
ATOM   7849 C CA  . ILE E 5 5   ? 151.420 159.427 200.777 1.00 124.62 ? 12  ILE L CA  1 
ATOM   7850 C C   . ILE E 5 5   ? 151.821 159.474 199.308 1.00 125.35 ? 12  ILE L C   1 
ATOM   7851 O O   . ILE E 5 5   ? 150.981 159.297 198.419 1.00 125.11 ? 12  ILE L O   1 
ATOM   7852 C CB  . ILE E 5 5   ? 149.889 159.446 200.932 1.00 124.77 ? 12  ILE L CB  1 
ATOM   7853 N N   . LEU E 5 6   ? 153.106 159.710 199.051 1.00 123.32 ? 13  LEU L N   1 
ATOM   7854 C CA  . LEU E 5 6   ? 153.647 159.793 197.695 1.00 123.99 ? 13  LEU L CA  1 
ATOM   7855 C C   . LEU E 5 6   ? 152.911 160.831 196.852 1.00 122.88 ? 13  LEU L C   1 
ATOM   7856 O O   . LEU E 5 6   ? 152.849 162.006 197.213 1.00 121.10 ? 13  LEU L O   1 
ATOM   7857 C CB  . LEU E 5 6   ? 153.594 158.425 197.008 1.00 122.49 ? 13  LEU L CB  1 
HETATM 7858 C C1  . PIO F 6 .   ? 133.662 150.368 161.421 1.00 93.73  ? 501 PIO R C1  1 
HETATM 7859 O O1  . PIO F 6 .   ? 134.773 149.606 161.303 1.00 97.40  ? 501 PIO R O1  1 
HETATM 7860 P P1  . PIO F 6 .   ? 136.275 150.374 161.253 1.00 100.04 ? 501 PIO R P1  1 
HETATM 7861 C C2  . PIO F 6 .   ? 132.460 149.494 161.922 1.00 92.67  ? 501 PIO R C2  1 
HETATM 7862 O O2  . PIO F 6 .   ? 132.790 148.943 163.150 1.00 92.19  ? 501 PIO R O2  1 
HETATM 7863 C C3  . PIO F 6 .   ? 132.114 148.354 160.950 1.00 93.66  ? 501 PIO R C3  1 
HETATM 7864 O O3  . PIO F 6 .   ? 132.996 147.260 161.204 1.00 93.30  ? 501 PIO R O3  1 
HETATM 7865 C C4  . PIO F 6 .   ? 132.228 148.743 159.504 1.00 91.82  ? 501 PIO R C4  1 
HETATM 7866 O O4  . PIO F 6 .   ? 131.170 148.088 158.741 1.00 92.69  ? 501 PIO R O4  1 
HETATM 7867 P P4  . PIO F 6 .   ? 129.613 148.646 158.759 1.00 96.64  ? 501 PIO R P4  1 
HETATM 7868 C C5  . PIO F 6 .   ? 132.193 150.219 159.257 1.00 91.45  ? 501 PIO R C5  1 
HETATM 7869 O O5  . PIO F 6 .   ? 132.387 150.430 157.851 1.00 91.41  ? 501 PIO R O5  1 
HETATM 7870 P P5  . PIO F 6 .   ? 131.944 151.871 157.161 1.00 94.87  ? 501 PIO R P5  1 
HETATM 7871 C C6  . PIO F 6 .   ? 133.281 150.990 160.025 1.00 92.77  ? 501 PIO R C6  1 
HETATM 7872 O O6  . PIO F 6 .   ? 132.834 152.291 160.240 1.00 90.43  ? 501 PIO R O6  1 
HETATM 7873 O O11 . PIO F 6 .   ? 136.948 150.072 159.933 1.00 91.86  ? 501 PIO R O11 1 
HETATM 7874 O O12 . PIO F 6 .   ? 136.095 151.865 161.392 1.00 93.41  ? 501 PIO R O12 1 
HETATM 7875 O O13 . PIO F 6 .   ? 137.225 149.816 162.523 1.00 92.88  ? 501 PIO R O13 1 
HETATM 7876 C C1A . PIO F 6 .   ? 139.244 151.781 164.501 1.00 94.14  ? 501 PIO R C1A 1 
HETATM 7877 O O1A . PIO F 6 .   ? 139.058 152.294 163.459 1.00 93.17  ? 501 PIO R O1A 1 
HETATM 7878 C C1B . PIO F 6 .   ? 133.522 150.976 165.384 1.00 93.72  ? 501 PIO R C1B 1 
HETATM 7879 O O1B . PIO F 6 .   ? 133.188 151.614 164.449 1.00 93.22  ? 501 PIO R O1B 1 
HETATM 7880 C C1C . PIO F 6 .   ? 136.651 149.811 163.841 1.00 92.92  ? 501 PIO R C1C 1 
HETATM 7881 C C2A . PIO F 6 .   ? 140.668 151.821 165.151 1.00 92.86  ? 501 PIO R C2A 1 
HETATM 7882 C C2B . PIO F 6 .   ? 132.520 150.661 166.502 1.00 91.65  ? 501 PIO R C2B 1 
HETATM 7883 C C2C . PIO F 6 .   ? 136.933 151.172 164.503 1.00 95.54  ? 501 PIO R C2C 1 
HETATM 7884 O O2C . PIO F 6 .   ? 138.174 151.117 165.180 1.00 96.10  ? 501 PIO R O2C 1 
HETATM 7885 C C3A . PIO F 6 .   ? 140.655 152.524 166.540 1.00 91.34  ? 501 PIO R C3A 1 
HETATM 7886 C C3B . PIO F 6 .   ? 131.199 150.082 165.974 1.00 91.28  ? 501 PIO R C3B 1 
HETATM 7887 C C3C . PIO F 6 .   ? 135.838 151.511 165.494 1.00 95.30  ? 501 PIO R C3C 1 
HETATM 7888 O O3C . PIO F 6 .   ? 134.854 150.494 165.473 1.00 96.63  ? 501 PIO R O3C 1 
HETATM 7889 O O41 . PIO F 6 .   ? 128.687 147.525 158.354 1.00 89.83  ? 501 PIO R O41 1 
HETATM 7890 O O42 . PIO F 6 .   ? 129.459 149.778 157.770 1.00 91.43  ? 501 PIO R O42 1 
HETATM 7891 O O43 . PIO F 6 .   ? 129.227 149.129 160.136 1.00 94.13  ? 501 PIO R O43 1 
HETATM 7892 C C4A . PIO F 6 .   ? 140.946 151.548 167.714 1.00 92.82  ? 501 PIO R C4A 1 
HETATM 7893 C C4B . PIO F 6 .   ? 130.182 151.164 165.624 1.00 91.37  ? 501 PIO R C4B 1 
HETATM 7894 O O51 . PIO F 6 .   ? 131.864 151.702 155.664 1.00 88.72  ? 501 PIO R O51 1 
HETATM 7895 O O52 . PIO F 6 .   ? 132.968 152.931 157.482 1.00 92.70  ? 501 PIO R O52 1 
HETATM 7896 O O53 . PIO F 6 .   ? 130.597 152.299 157.698 1.00 91.72  ? 501 PIO R O53 1 
HETATM 7897 C C5A . PIO F 6 .   ? 140.587 150.095 167.378 1.00 92.81  ? 501 PIO R C5A 1 
HETATM 7898 C C1  . SRW G 7 .   ? 149.339 142.799 177.404 1.00 91.56  ? 502 SRW R C1  1 
HETATM 7899 O O1  . SRW G 7 .   ? 149.680 142.284 176.131 1.00 92.23  ? 502 SRW R O1  1 
HETATM 7900 C C2  . SRW G 7 .   ? 149.310 140.933 175.923 1.00 93.46  ? 502 SRW R C2  1 
HETATM 7901 C C3  . SRW G 7 .   ? 149.502 140.343 174.665 1.00 93.15  ? 502 SRW R C3  1 
HETATM 7902 C C4  . SRW G 7 .   ? 149.138 139.014 174.456 1.00 93.18  ? 502 SRW R C4  1 
HETATM 7903 C C5  . SRW G 7 .   ? 148.584 138.267 175.499 1.00 93.40  ? 502 SRW R C5  1 
HETATM 7904 C C6  . SRW G 7 .   ? 148.395 138.853 176.754 1.00 93.26  ? 502 SRW R C6  1 
HETATM 7905 C C7  . SRW G 7 .   ? 148.756 140.184 176.964 1.00 93.15  ? 502 SRW R C7  1 
HETATM 7906 C C8  . SRW G 7 .   ? 150.144 141.205 173.443 1.00 92.32  ? 502 SRW R C8  1 
HETATM 7907 C C9  . SRW G 7 .   ? 149.034 141.644 172.599 1.00 92.76  ? 502 SRW R C9  1 
HETATM 7908 C C10 . SRW G 7 .   ? 149.455 142.141 171.208 1.00 93.24  ? 502 SRW R C10 1 
HETATM 7909 N N1  . SRW G 7 .   ? 150.266 141.074 170.431 1.00 92.58  ? 502 SRW R N1  1 
HETATM 7910 C C11 . SRW G 7 .   ? 151.487 140.737 171.310 1.00 93.61  ? 502 SRW R C11 1 
HETATM 7911 C C12 . SRW G 7 .   ? 151.152 140.355 172.762 1.00 92.38  ? 502 SRW R C12 1 
HETATM 7912 C C13 . SRW G 7 .   ? 149.527 139.941 169.813 1.00 91.51  ? 502 SRW R C13 1 
HETATM 7913 N N2  . SRW G 7 .   ? 149.666 138.721 170.332 1.00 92.55  ? 502 SRW R N2  1 
HETATM 7914 C C14 . SRW G 7 .   ? 149.024 137.658 169.826 1.00 93.25  ? 502 SRW R C14 1 
HETATM 7915 N N3  . SRW G 7 .   ? 148.215 137.770 168.770 1.00 92.24  ? 502 SRW R N3  1 
HETATM 7916 C C15 . SRW G 7 .   ? 148.017 138.994 168.178 1.00 93.31  ? 502 SRW R C15 1 
HETATM 7917 C C16 . SRW G 7 .   ? 148.654 140.113 168.665 1.00 91.74  ? 502 SRW R C16 1 
HETATM 7918 C C17 . SRW G 7 .   ? 148.437 141.385 168.031 1.00 90.59  ? 502 SRW R C17 1 
HETATM 7919 C C18 . SRW G 7 .   ? 147.576 141.485 166.918 1.00 91.80  ? 502 SRW R C18 1 
HETATM 7920 C C19 . SRW G 7 .   ? 146.930 140.340 166.425 1.00 92.92  ? 502 SRW R C19 1 
HETATM 7921 C C20 . SRW G 7 .   ? 147.139 139.097 167.041 1.00 93.72  ? 502 SRW R C20 1 
HETATM 7922 N N4  . SRW G 7 .   ? 147.346 142.785 166.256 1.00 93.67  ? 502 SRW R N4  1 
HETATM 7923 C C21 . SRW G 7 .   ? 146.041 143.449 166.367 1.00 93.36  ? 502 SRW R C21 1 
HETATM 7924 C C22 . SRW G 7 .   ? 148.425 143.407 165.466 1.00 93.23  ? 502 SRW R C22 1 
HETATM 7925 C C23 . SRW G 7 .   ? 149.395 144.187 166.379 1.00 91.87  ? 502 SRW R C23 1 
HETATM 7926 O O2  . SRW G 7 .   ? 150.367 143.650 166.802 1.00 90.80  ? 502 SRW R O2  1 
HETATM 7927 C C24 . SRW G 7 .   ? 149.239 136.279 170.475 1.00 93.61  ? 502 SRW R C24 1 
HETATM 7928 F F1  . SRW G 7 .   ? 148.879 135.299 169.592 1.00 94.08  ? 502 SRW R F1  1 
HETATM 7929 C C25 . SRW G 7 .   ? 150.558 135.875 171.142 1.00 92.60  ? 502 SRW R C25 1 
HETATM 7930 C C26 . SRW G 7 .   ? 149.242 135.714 171.900 1.00 93.19  ? 502 SRW R C26 1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
7755 N N   . TPO D 546 ? 26.3994 26.3994 26.3994 0.0000 0.0000 0.0000 407 TPO R N   
7756 C CA  . TPO D 546 ? 26.8207 26.8207 26.8207 0.0000 0.0000 0.0000 407 TPO R CA  
7757 C CB  . TPO D 546 ? 27.4251 27.4251 27.4251 0.0000 0.0000 0.0000 407 TPO R CB  
7758 C CG2 . TPO D 546 ? 26.6789 26.6789 26.6789 0.0000 0.0000 0.0000 407 TPO R CG2 
7759 O OG1 . TPO D 546 ? 26.8590 26.8590 26.8590 0.0000 0.0000 0.0000 407 TPO R OG1 
7760 P P   . TPO D 546 ? 27.8305 27.8305 27.8305 0.0000 0.0000 0.0000 407 TPO R P   
7761 O O1P . TPO D 546 ? 28.6130 28.6130 28.6130 0.0000 0.0000 0.0000 407 TPO R O1P 
7762 O O2P . TPO D 546 ? 27.2277 27.2277 27.2277 0.0000 0.0000 0.0000 407 TPO R O2P 
7763 O O3P . TPO D 546 ? 27.8950 27.8950 27.8950 0.0000 0.0000 0.0000 407 TPO R O3P 
7764 C C   . TPO D 546 ? 27.6401 27.6401 27.6401 0.0000 0.0000 0.0000 407 TPO R C   
7765 O O   . TPO D 546 ? 28.0936 28.0936 28.0936 0.0000 0.0000 0.0000 407 TPO R O   
7766 N N   . LEU D 547 ? 26.5788 26.5788 26.5788 0.0000 0.0000 0.0000 408 LEU R N   
7767 C CA  . LEU D 547 ? 26.3470 26.3470 26.3470 0.0000 0.0000 0.0000 408 LEU R CA  
7768 C C   . LEU D 547 ? 26.8216 26.8216 26.8216 0.0000 0.0000 0.0000 408 LEU R C   
7769 O O   . LEU D 547 ? 26.5267 26.5267 26.5267 0.0000 0.0000 0.0000 408 LEU R O   
7774 N N   . SEP D 548 ? 27.8344 27.8344 27.8344 0.0000 0.0000 0.0000 409 SEP R N   
7775 C CA  . SEP D 548 ? 27.6750 27.6750 27.6750 0.0000 0.0000 0.0000 409 SEP R CA  
7776 C CB  . SEP D 548 ? 28.5642 28.5642 28.5642 0.0000 0.0000 0.0000 409 SEP R CB  
7777 O OG  . SEP D 548 ? 28.7501 28.7501 28.7501 0.0000 0.0000 0.0000 409 SEP R OG  
7778 C C   . SEP D 548 ? 27.6658 27.6658 27.6658 0.0000 0.0000 0.0000 409 SEP R C   
7779 O O   . SEP D 548 ? 28.0842 28.0842 28.0842 0.0000 0.0000 0.0000 409 SEP R O   
7780 P P   . SEP D 548 ? 26.0300 26.0300 26.0300 0.0000 0.0000 0.0000 409 SEP R P   
7781 O O1P . SEP D 548 ? 26.4922 26.4922 26.4922 0.0000 0.0000 0.0000 409 SEP R O1P 
7782 O O2P . SEP D 548 ? 27.9469 27.9469 27.9469 0.0000 0.0000 0.0000 409 SEP R O2P 
7783 O O3P . SEP D 548 ? 25.7471 25.7471 25.7471 0.0000 0.0000 0.0000 409 SEP R O3P 
7784 N N   . SEP D 549 ? 27.0596 27.0596 27.0596 0.0000 0.0000 0.0000 410 SEP R N   
7785 C CA  . SEP D 549 ? 26.4074 26.4074 26.4074 0.0000 0.0000 0.0000 410 SEP R CA  
7786 C CB  . SEP D 549 ? 27.1600 27.1600 27.1600 0.0000 0.0000 0.0000 410 SEP R CB  
7787 O OG  . SEP D 549 ? 27.3769 27.3769 27.3769 0.0000 0.0000 0.0000 410 SEP R OG  
7788 C C   . SEP D 549 ? 24.5301 24.5301 24.5301 0.0000 0.0000 0.0000 410 SEP R C   
7789 O O   . SEP D 549 ? 24.3294 24.3294 24.3294 0.0000 0.0000 0.0000 410 SEP R O   
7790 P P   . SEP D 549 ? 27.6759 27.6759 27.6759 0.0000 0.0000 0.0000 410 SEP R P   
7791 O O1P . SEP D 549 ? 28.1887 28.1887 28.1887 0.0000 0.0000 0.0000 410 SEP R O1P 
7792 O O2P . SEP D 549 ? 28.0182 28.0182 28.0182 0.0000 0.0000 0.0000 410 SEP R O2P 
7793 O O3P . SEP D 549 ? 27.2936 27.2936 27.2936 0.0000 0.0000 0.0000 410 SEP R O3P 
# 
