data_8ZWP
# 
_entry.id   8ZWP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZWP         pdb_00008zwp 10.2210/pdb8zwp/pdb 
WWPDB D_1300047691 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-09 ? 
2 'Structure model' 1 1 2025-04-16 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZWP 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              cma@gate.sinica.edu.tw 
_pdbx_contact_author.name_first         Che 
_pdbx_contact_author.name_last          Ma 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-4741-2307 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lo, J.M.' 1 0000-0002-3002-9491 
'Ma, C.'   2 0000-0002-4741-2307 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Am.Chem.Soc. 
_citation.journal_id_ASTM           JACSAT 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1520-5126 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            147 
_citation.language                  ? 
_citation.page_first                10875 
_citation.page_last                 10885 
_citation.title                     'Structure-Based Mechanism and Specificity of Human Galactosyltransferase beta 3GalT5.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacs.4c11724 
_citation.pdbx_database_id_PubMed   40130308 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lo, J.M.'    1 ? 
primary 'Kung, C.C.'  2 ? 
primary 'Cheng, T.R.' 3 ? 
primary 'Wong, C.H.'  4 ? 
primary 'Ma, C.'      5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1  polymer     man 'Beta-1,3-galactosyltransferase 5' 32550.551 2   2.4.1.- ? ? ? 
2  branched    syn 
'2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose' 
707.630   2   ?       ? ? ? 
3  branched    syn '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   2   ?       
? ? ? 
4  branched    syn 
'2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose' 570.542   1 
?       ? ? ? 
5  branched    syn 
;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
;
1056.964  1   ?       ? ? ? 
6  non-polymer syn 'MANGANESE (II) ION' 54.938    2   ?       ? ? ? 
7  non-polymer syn "URIDINE-5'-DIPHOSPHATE" 404.161   2   ?       ? ? ? 
8  non-polymer syn '2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL' 282.334   2   ? 
? ? ? 
9  non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   1   ?       ? ? ? 
10 water       nat water 18.015    296 ?       ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Beta-1,3-GalTase 5,Beta3Gal-T5,Beta3GalT5,b3Gal-T5,Beta-3-Gx-T5,UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5,UDP-galactose:beta-N-acetylglucosamine beta-1
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;FKEQSFVYKKDGNFLKLPDTDCRQTPPFLVLLVTSSHKQLAERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAETKEVD
QESQRHGDIIQKDFLDVYYNLTLKTMMGIEWVHRFCPQAAFVMKTDSDMFINVDYLTELLLKKNRTTRFFTGFLKLNEFP
IRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVASQVYNVSKSVPYIKLEDVFVGLCLERLNIRLEELHSQPTFFPGG
LRFSVCLFRRIVACHFIKPRTLLDYWQALENSRGEDCP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;FKEQSFVYKKDGNFLKLPDTDCRQTPPFLVLLVTSSHKQLAERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAETKEVD
QESQRHGDIIQKDFLDVYYNLTLKTMMGIEWVHRFCPQAAFVMKTDSDMFINVDYLTELLLKKNRTTRFFTGFLKLNEFP
IRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVASQVYNVSKSVPYIKLEDVFVGLCLERLNIRLEELHSQPTFFPGG
LRFSVCLFRRIVACHFIKPRTLLDYWQALENSRGEDCP
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
6  'MANGANESE (II) ION'                                                                            MN  
7  "URIDINE-5'-DIPHOSPHATE"                                                                        UDP 
8  '2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL' B3P 
9  2-acetamido-2-deoxy-beta-D-glucopyranose                                                        NAG 
10 water                                                                                           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PHE n 
1 2   LYS n 
1 3   GLU n 
1 4   GLN n 
1 5   SER n 
1 6   PHE n 
1 7   VAL n 
1 8   TYR n 
1 9   LYS n 
1 10  LYS n 
1 11  ASP n 
1 12  GLY n 
1 13  ASN n 
1 14  PHE n 
1 15  LEU n 
1 16  LYS n 
1 17  LEU n 
1 18  PRO n 
1 19  ASP n 
1 20  THR n 
1 21  ASP n 
1 22  CYS n 
1 23  ARG n 
1 24  GLN n 
1 25  THR n 
1 26  PRO n 
1 27  PRO n 
1 28  PHE n 
1 29  LEU n 
1 30  VAL n 
1 31  LEU n 
1 32  LEU n 
1 33  VAL n 
1 34  THR n 
1 35  SER n 
1 36  SER n 
1 37  HIS n 
1 38  LYS n 
1 39  GLN n 
1 40  LEU n 
1 41  ALA n 
1 42  GLU n 
1 43  ARG n 
1 44  MET n 
1 45  ALA n 
1 46  ILE n 
1 47  ARG n 
1 48  GLN n 
1 49  THR n 
1 50  TRP n 
1 51  GLY n 
1 52  LYS n 
1 53  GLU n 
1 54  ARG n 
1 55  MET n 
1 56  VAL n 
1 57  LYS n 
1 58  GLY n 
1 59  LYS n 
1 60  GLN n 
1 61  LEU n 
1 62  LYS n 
1 63  THR n 
1 64  PHE n 
1 65  PHE n 
1 66  LEU n 
1 67  LEU n 
1 68  GLY n 
1 69  THR n 
1 70  THR n 
1 71  SER n 
1 72  SER n 
1 73  ALA n 
1 74  ALA n 
1 75  GLU n 
1 76  THR n 
1 77  LYS n 
1 78  GLU n 
1 79  VAL n 
1 80  ASP n 
1 81  GLN n 
1 82  GLU n 
1 83  SER n 
1 84  GLN n 
1 85  ARG n 
1 86  HIS n 
1 87  GLY n 
1 88  ASP n 
1 89  ILE n 
1 90  ILE n 
1 91  GLN n 
1 92  LYS n 
1 93  ASP n 
1 94  PHE n 
1 95  LEU n 
1 96  ASP n 
1 97  VAL n 
1 98  TYR n 
1 99  TYR n 
1 100 ASN n 
1 101 LEU n 
1 102 THR n 
1 103 LEU n 
1 104 LYS n 
1 105 THR n 
1 106 MET n 
1 107 MET n 
1 108 GLY n 
1 109 ILE n 
1 110 GLU n 
1 111 TRP n 
1 112 VAL n 
1 113 HIS n 
1 114 ARG n 
1 115 PHE n 
1 116 CYS n 
1 117 PRO n 
1 118 GLN n 
1 119 ALA n 
1 120 ALA n 
1 121 PHE n 
1 122 VAL n 
1 123 MET n 
1 124 LYS n 
1 125 THR n 
1 126 ASP n 
1 127 SER n 
1 128 ASP n 
1 129 MET n 
1 130 PHE n 
1 131 ILE n 
1 132 ASN n 
1 133 VAL n 
1 134 ASP n 
1 135 TYR n 
1 136 LEU n 
1 137 THR n 
1 138 GLU n 
1 139 LEU n 
1 140 LEU n 
1 141 LEU n 
1 142 LYS n 
1 143 LYS n 
1 144 ASN n 
1 145 ARG n 
1 146 THR n 
1 147 THR n 
1 148 ARG n 
1 149 PHE n 
1 150 PHE n 
1 151 THR n 
1 152 GLY n 
1 153 PHE n 
1 154 LEU n 
1 155 LYS n 
1 156 LEU n 
1 157 ASN n 
1 158 GLU n 
1 159 PHE n 
1 160 PRO n 
1 161 ILE n 
1 162 ARG n 
1 163 GLN n 
1 164 PRO n 
1 165 PHE n 
1 166 SER n 
1 167 LYS n 
1 168 TRP n 
1 169 PHE n 
1 170 VAL n 
1 171 SER n 
1 172 LYS n 
1 173 SER n 
1 174 GLU n 
1 175 TYR n 
1 176 PRO n 
1 177 TRP n 
1 178 ASP n 
1 179 ARG n 
1 180 TYR n 
1 181 PRO n 
1 182 PRO n 
1 183 PHE n 
1 184 CYS n 
1 185 SER n 
1 186 GLY n 
1 187 THR n 
1 188 GLY n 
1 189 TYR n 
1 190 VAL n 
1 191 PHE n 
1 192 SER n 
1 193 GLY n 
1 194 ASP n 
1 195 VAL n 
1 196 ALA n 
1 197 SER n 
1 198 GLN n 
1 199 VAL n 
1 200 TYR n 
1 201 ASN n 
1 202 VAL n 
1 203 SER n 
1 204 LYS n 
1 205 SER n 
1 206 VAL n 
1 207 PRO n 
1 208 TYR n 
1 209 ILE n 
1 210 LYS n 
1 211 LEU n 
1 212 GLU n 
1 213 ASP n 
1 214 VAL n 
1 215 PHE n 
1 216 VAL n 
1 217 GLY n 
1 218 LEU n 
1 219 CYS n 
1 220 LEU n 
1 221 GLU n 
1 222 ARG n 
1 223 LEU n 
1 224 ASN n 
1 225 ILE n 
1 226 ARG n 
1 227 LEU n 
1 228 GLU n 
1 229 GLU n 
1 230 LEU n 
1 231 HIS n 
1 232 SER n 
1 233 GLN n 
1 234 PRO n 
1 235 THR n 
1 236 PHE n 
1 237 PHE n 
1 238 PRO n 
1 239 GLY n 
1 240 GLY n 
1 241 LEU n 
1 242 ARG n 
1 243 PHE n 
1 244 SER n 
1 245 VAL n 
1 246 CYS n 
1 247 LEU n 
1 248 PHE n 
1 249 ARG n 
1 250 ARG n 
1 251 ILE n 
1 252 VAL n 
1 253 ALA n 
1 254 CYS n 
1 255 HIS n 
1 256 PHE n 
1 257 ILE n 
1 258 LYS n 
1 259 PRO n 
1 260 ARG n 
1 261 THR n 
1 262 LEU n 
1 263 LEU n 
1 264 ASP n 
1 265 TYR n 
1 266 TRP n 
1 267 GLN n 
1 268 ALA n 
1 269 LEU n 
1 270 GLU n 
1 271 ASN n 
1 272 SER n 
1 273 ARG n 
1 274 GLY n 
1 275 GLU n 
1 276 ASP n 
1 277 CYS n 
1 278 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   278 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 B3GALT5 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            Sf9 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
4 oligosaccharide 
5 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1  2 DGalpNAcb1-3DGalpa1-4DGalpb1-4DGlcpb1-ROH 'Glycam Condensed Sequence' GMML       1.0   
2  2 'WURCS=2.0/4,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][a2112h-1a_1-5][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4/a4-b1_b4-c1_c3-d1' WURCS 
PDB2Glycan 1.1.0 
3  2 '[][b-D-Glcp]{[(4+1)][b-D-Galp]{[(4+1)][a-D-Galp]{[(3+1)][b-D-GalpNAc]{}}}}' LINUCS                      PDB-CARE   ?     
4  3 DGlcpNAcb1-4DGlcpNAcb1-ROH 'Glycam Condensed Sequence' GMML       1.0   
5  3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
6  3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}' LINUCS                      PDB-CARE   ?     
7  4 'DGlcpNAcb1-4[LFucpa1-6]DGlcpNAcb1-ROH' 'Glycam Condensed Sequence' GMML       1.0   
8  4 'WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5]/1-1-2/a4-b1_a6-c1' WURCS                       PDB2Glycan 1.1.0 
9  4 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}[(6+1)][a-L-Fucp]{}}' LINUCS                      PDB-CARE   ?     
10 5 'DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4[LFucpa1-6]DGlcpNAcb1-ROH' 'Glycam Condensed Sequence' GMML       1.0   
11 5 
'WURCS=2.0/4,6,5/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5][a1221m-1a_1-5]/1-1-2-3-3-4/a4-b1_a6-f1_b4-c1_c3-d1_c6-e1' 
WURCS                       PDB2Glycan 1.1.0 
12 5 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}[(6+1)][a-L-Fucp]{}}' 
LINUCS                      PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1  2 2 GAL C1 O1 1 BGC O4 HO4 sing ? 
2  2 3 GLA C1 O1 2 GAL O4 HO4 sing ? 
3  2 4 NGA C1 O1 3 GLA O3 HO3 sing ? 
4  3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
5  4 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
6  4 3 FUC C1 O1 1 NAG O6 HO6 sing ? 
7  5 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
8  5 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
9  5 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
10 5 5 MAN C1 O1 3 BMA O6 HO6 sing ? 
11 5 6 FUC C1 O1 1 NAG O6 HO6 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE ? 'C3 H7 N O2'       89.093  
ARG 'L-peptide linking'           y ARGININE ? 'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking'           y ASPARAGINE ? 'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID' ? 'C4 H7 N O4'       133.103 
B3P non-polymer                   . 
'2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL' ? 'C11 H26 N2 O6'    282.334 
BGC 'D-saccharide, beta linking'  . beta-D-glucopyranose 'beta-D-glucose; D-glucose; glucose' 'C6 H12 O6'        180.156 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose 'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'        180.156 
CYS 'L-peptide linking'           y CYSTEINE ? 'C3 H7 N O2 S'     121.158 
FUC 'L-saccharide, alpha linking' . alpha-L-fucopyranose 'alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose' 
'C6 H12 O5'        164.156 
GAL 'D-saccharide, beta linking'  . beta-D-galactopyranose 'beta-D-galactose; D-galactose; galactose' 'C6 H12 O6'        180.156 
GLA 'D-saccharide, alpha linking' . alpha-D-galactopyranose 'alpha-D-galactose; D-galactose; galactose; ALPHA D-GALACTOSE' 
'C6 H12 O6'        180.156 
GLN 'L-peptide linking'           y GLUTAMINE ? 'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID' ? 'C5 H9 N O4'       147.129 
GLY 'peptide linking'             y GLYCINE ? 'C2 H5 N O2'       75.067  
HIS 'L-peptide linking'           y HISTIDINE ? 'C6 H10 N3 O2 1'   156.162 
HOH non-polymer                   . WATER ? 'H2 O'             18.015  
ILE 'L-peptide linking'           y ISOLEUCINE ? 'C6 H13 N O2'      131.173 
LEU 'L-peptide linking'           y LEUCINE ? 'C6 H13 N O2'      131.173 
LYS 'L-peptide linking'           y LYSINE ? 'C6 H15 N2 O2 1'   147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose 'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6'        180.156 
MET 'L-peptide linking'           y METHIONINE ? 'C5 H11 N O2 S'    149.211 
MN  non-polymer                   . 'MANGANESE (II) ION' ? 'Mn 2'             54.938  
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'      221.208 
NGA 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-galactopyranose 
;N-acetyl-beta-D-galactosamine; 2-acetamido-2-deoxy-beta-D-galactose; 2-acetamido-2-deoxy-D-galactose; 2-acetamido-2-deoxy-galactose; N-ACETYL-D-GALACTOSAMINE
;
'C8 H15 N O6'      221.208 
PHE 'L-peptide linking'           y PHENYLALANINE ? 'C9 H11 N O2'      165.189 
PRO 'L-peptide linking'           y PROLINE ? 'C5 H9 N O2'       115.130 
SER 'L-peptide linking'           y SERINE ? 'C3 H7 N O3'       105.093 
THR 'L-peptide linking'           y THREONINE ? 'C4 H9 N O3'       119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN ? 'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking'           y TYROSINE ? 'C9 H11 N O3'      181.189 
UDP 'RNA linking'                 . "URIDINE-5'-DIPHOSPHATE" ? 'C9 H14 N2 O12 P2' 404.161 
VAL 'L-peptide linking'           y VALINE ? 'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BGC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpb                           
BGC 'COMMON NAME'                         GMML     1.0 b-D-glucopyranose                
BGC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Glcp                         
BGC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Glc                              
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                           
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose                
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                         
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                              
FUC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LFucpa                           
FUC 'COMMON NAME'                         GMML     1.0 a-L-fucopyranose                 
FUC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Fucp                         
FUC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fuc                              
GAL 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpb                           
GAL 'COMMON NAME'                         GMML     1.0 b-D-galactopyranose              
GAL 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Galp                         
GAL 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Gal                              
GLA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpa                           
GLA 'COMMON NAME'                         GMML     1.0 a-D-galactopyranose              
GLA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Galp                         
GLA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Gal                              
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                           
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose                
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                         
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                              
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                        
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine   
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                      
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                           
NGA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpNAcb                        
NGA 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-galactopyranosamine 
NGA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GalpNAc                      
NGA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GalNAc                           
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PHE 1   31  ?   ?   ?   A . n 
A 1 2   LYS 2   32  ?   ?   ?   A . n 
A 1 3   GLU 3   33  ?   ?   ?   A . n 
A 1 4   GLN 4   34  ?   ?   ?   A . n 
A 1 5   SER 5   35  ?   ?   ?   A . n 
A 1 6   PHE 6   36  ?   ?   ?   A . n 
A 1 7   VAL 7   37  ?   ?   ?   A . n 
A 1 8   TYR 8   38  ?   ?   ?   A . n 
A 1 9   LYS 9   39  ?   ?   ?   A . n 
A 1 10  LYS 10  40  ?   ?   ?   A . n 
A 1 11  ASP 11  41  ?   ?   ?   A . n 
A 1 12  GLY 12  42  42  GLY GLY A . n 
A 1 13  ASN 13  43  43  ASN ASN A . n 
A 1 14  PHE 14  44  44  PHE PHE A . n 
A 1 15  LEU 15  45  45  LEU LEU A . n 
A 1 16  LYS 16  46  46  LYS LYS A . n 
A 1 17  LEU 17  47  47  LEU LEU A . n 
A 1 18  PRO 18  48  48  PRO PRO A . n 
A 1 19  ASP 19  49  49  ASP ASP A . n 
A 1 20  THR 20  50  50  THR THR A . n 
A 1 21  ASP 21  51  51  ASP ASP A . n 
A 1 22  CYS 22  52  52  CYS CYS A . n 
A 1 23  ARG 23  53  53  ARG ARG A . n 
A 1 24  GLN 24  54  54  GLN GLN A . n 
A 1 25  THR 25  55  55  THR THR A . n 
A 1 26  PRO 26  56  56  PRO PRO A . n 
A 1 27  PRO 27  57  57  PRO PRO A . n 
A 1 28  PHE 28  58  58  PHE PHE A . n 
A 1 29  LEU 29  59  59  LEU LEU A . n 
A 1 30  VAL 30  60  60  VAL VAL A . n 
A 1 31  LEU 31  61  61  LEU LEU A . n 
A 1 32  LEU 32  62  62  LEU LEU A . n 
A 1 33  VAL 33  63  63  VAL VAL A . n 
A 1 34  THR 34  64  64  THR THR A . n 
A 1 35  SER 35  65  65  SER SER A . n 
A 1 36  SER 36  66  66  SER SER A . n 
A 1 37  HIS 37  67  67  HIS HIS A . n 
A 1 38  LYS 38  68  68  LYS LYS A . n 
A 1 39  GLN 39  69  69  GLN GLN A . n 
A 1 40  LEU 40  70  70  LEU LEU A . n 
A 1 41  ALA 41  71  71  ALA ALA A . n 
A 1 42  GLU 42  72  72  GLU GLU A . n 
A 1 43  ARG 43  73  73  ARG ARG A . n 
A 1 44  MET 44  74  74  MET MET A . n 
A 1 45  ALA 45  75  75  ALA ALA A . n 
A 1 46  ILE 46  76  76  ILE ILE A . n 
A 1 47  ARG 47  77  77  ARG ARG A . n 
A 1 48  GLN 48  78  78  GLN GLN A . n 
A 1 49  THR 49  79  79  THR THR A . n 
A 1 50  TRP 50  80  80  TRP TRP A . n 
A 1 51  GLY 51  81  81  GLY GLY A . n 
A 1 52  LYS 52  82  82  LYS LYS A . n 
A 1 53  GLU 53  83  83  GLU GLU A . n 
A 1 54  ARG 54  84  84  ARG ARG A . n 
A 1 55  MET 55  85  85  MET MET A . n 
A 1 56  VAL 56  86  86  VAL VAL A . n 
A 1 57  LYS 57  87  87  LYS LYS A . n 
A 1 58  GLY 58  88  88  GLY GLY A . n 
A 1 59  LYS 59  89  89  LYS LYS A . n 
A 1 60  GLN 60  90  90  GLN GLN A . n 
A 1 61  LEU 61  91  91  LEU LEU A . n 
A 1 62  LYS 62  92  92  LYS LYS A . n 
A 1 63  THR 63  93  93  THR THR A . n 
A 1 64  PHE 64  94  94  PHE PHE A . n 
A 1 65  PHE 65  95  95  PHE PHE A . n 
A 1 66  LEU 66  96  96  LEU LEU A . n 
A 1 67  LEU 67  97  97  LEU LEU A . n 
A 1 68  GLY 68  98  98  GLY GLY A . n 
A 1 69  THR 69  99  99  THR THR A . n 
A 1 70  THR 70  100 100 THR THR A . n 
A 1 71  SER 71  101 101 SER SER A . n 
A 1 72  SER 72  102 102 SER SER A . n 
A 1 73  ALA 73  103 103 ALA ALA A . n 
A 1 74  ALA 74  104 104 ALA ALA A . n 
A 1 75  GLU 75  105 105 GLU GLU A . n 
A 1 76  THR 76  106 106 THR THR A . n 
A 1 77  LYS 77  107 107 LYS LYS A . n 
A 1 78  GLU 78  108 108 GLU GLU A . n 
A 1 79  VAL 79  109 109 VAL VAL A . n 
A 1 80  ASP 80  110 110 ASP ASP A . n 
A 1 81  GLN 81  111 111 GLN GLN A . n 
A 1 82  GLU 82  112 112 GLU GLU A . n 
A 1 83  SER 83  113 113 SER SER A . n 
A 1 84  GLN 84  114 114 GLN GLN A . n 
A 1 85  ARG 85  115 115 ARG ARG A . n 
A 1 86  HIS 86  116 116 HIS HIS A . n 
A 1 87  GLY 87  117 117 GLY GLY A . n 
A 1 88  ASP 88  118 118 ASP ASP A . n 
A 1 89  ILE 89  119 119 ILE ILE A . n 
A 1 90  ILE 90  120 120 ILE ILE A . n 
A 1 91  GLN 91  121 121 GLN GLN A . n 
A 1 92  LYS 92  122 122 LYS LYS A . n 
A 1 93  ASP 93  123 123 ASP ASP A . n 
A 1 94  PHE 94  124 124 PHE PHE A . n 
A 1 95  LEU 95  125 125 LEU LEU A . n 
A 1 96  ASP 96  126 126 ASP ASP A . n 
A 1 97  VAL 97  127 127 VAL VAL A . n 
A 1 98  TYR 98  128 128 TYR TYR A . n 
A 1 99  TYR 99  129 129 TYR TYR A . n 
A 1 100 ASN 100 130 130 ASN ASN A . n 
A 1 101 LEU 101 131 131 LEU LEU A . n 
A 1 102 THR 102 132 132 THR THR A . n 
A 1 103 LEU 103 133 133 LEU LEU A . n 
A 1 104 LYS 104 134 134 LYS LYS A . n 
A 1 105 THR 105 135 135 THR THR A . n 
A 1 106 MET 106 136 136 MET MET A . n 
A 1 107 MET 107 137 137 MET MET A . n 
A 1 108 GLY 108 138 138 GLY GLY A . n 
A 1 109 ILE 109 139 139 ILE ILE A . n 
A 1 110 GLU 110 140 140 GLU GLU A . n 
A 1 111 TRP 111 141 141 TRP TRP A . n 
A 1 112 VAL 112 142 142 VAL VAL A . n 
A 1 113 HIS 113 143 143 HIS HIS A . n 
A 1 114 ARG 114 144 144 ARG ARG A . n 
A 1 115 PHE 115 145 145 PHE PHE A . n 
A 1 116 CYS 116 146 146 CYS CYS A . n 
A 1 117 PRO 117 147 147 PRO PRO A . n 
A 1 118 GLN 118 148 148 GLN GLN A . n 
A 1 119 ALA 119 149 149 ALA ALA A . n 
A 1 120 ALA 120 150 150 ALA ALA A . n 
A 1 121 PHE 121 151 151 PHE PHE A . n 
A 1 122 VAL 122 152 152 VAL VAL A . n 
A 1 123 MET 123 153 153 MET MET A . n 
A 1 124 LYS 124 154 154 LYS LYS A . n 
A 1 125 THR 125 155 155 THR THR A . n 
A 1 126 ASP 126 156 156 ASP ASP A . n 
A 1 127 SER 127 157 157 SER SER A . n 
A 1 128 ASP 128 158 158 ASP ASP A . n 
A 1 129 MET 129 159 159 MET MET A . n 
A 1 130 PHE 130 160 160 PHE PHE A . n 
A 1 131 ILE 131 161 161 ILE ILE A . n 
A 1 132 ASN 132 162 162 ASN ASN A . n 
A 1 133 VAL 133 163 163 VAL VAL A . n 
A 1 134 ASP 134 164 164 ASP ASP A . n 
A 1 135 TYR 135 165 165 TYR TYR A . n 
A 1 136 LEU 136 166 166 LEU LEU A . n 
A 1 137 THR 137 167 167 THR THR A . n 
A 1 138 GLU 138 168 168 GLU GLU A . n 
A 1 139 LEU 139 169 169 LEU LEU A . n 
A 1 140 LEU 140 170 170 LEU LEU A . n 
A 1 141 LEU 141 171 171 LEU LEU A . n 
A 1 142 LYS 142 172 172 LYS LYS A . n 
A 1 143 LYS 143 173 173 LYS LYS A . n 
A 1 144 ASN 144 174 174 ASN ASN A . n 
A 1 145 ARG 145 175 175 ARG ARG A . n 
A 1 146 THR 146 176 176 THR THR A . n 
A 1 147 THR 147 177 177 THR THR A . n 
A 1 148 ARG 148 178 178 ARG ARG A . n 
A 1 149 PHE 149 179 179 PHE PHE A . n 
A 1 150 PHE 150 180 180 PHE PHE A . n 
A 1 151 THR 151 181 181 THR THR A . n 
A 1 152 GLY 152 182 182 GLY GLY A . n 
A 1 153 PHE 153 183 183 PHE PHE A . n 
A 1 154 LEU 154 184 184 LEU LEU A . n 
A 1 155 LYS 155 185 185 LYS LYS A . n 
A 1 156 LEU 156 186 186 LEU LEU A . n 
A 1 157 ASN 157 187 187 ASN ASN A . n 
A 1 158 GLU 158 188 188 GLU GLU A . n 
A 1 159 PHE 159 189 189 PHE PHE A . n 
A 1 160 PRO 160 190 190 PRO PRO A . n 
A 1 161 ILE 161 191 191 ILE ILE A . n 
A 1 162 ARG 162 192 192 ARG ARG A . n 
A 1 163 GLN 163 193 193 GLN GLN A . n 
A 1 164 PRO 164 194 194 PRO PRO A . n 
A 1 165 PHE 165 195 195 PHE PHE A . n 
A 1 166 SER 166 196 196 SER SER A . n 
A 1 167 LYS 167 197 197 LYS LYS A . n 
A 1 168 TRP 168 198 198 TRP TRP A . n 
A 1 169 PHE 169 199 199 PHE PHE A . n 
A 1 170 VAL 170 200 200 VAL VAL A . n 
A 1 171 SER 171 201 201 SER SER A . n 
A 1 172 LYS 172 202 202 LYS LYS A . n 
A 1 173 SER 173 203 203 SER SER A . n 
A 1 174 GLU 174 204 204 GLU GLU A . n 
A 1 175 TYR 175 205 205 TYR TYR A . n 
A 1 176 PRO 176 206 206 PRO PRO A . n 
A 1 177 TRP 177 207 207 TRP TRP A . n 
A 1 178 ASP 178 208 208 ASP ASP A . n 
A 1 179 ARG 179 209 209 ARG ARG A . n 
A 1 180 TYR 180 210 210 TYR TYR A . n 
A 1 181 PRO 181 211 211 PRO PRO A . n 
A 1 182 PRO 182 212 212 PRO PRO A . n 
A 1 183 PHE 183 213 213 PHE PHE A . n 
A 1 184 CYS 184 214 214 CYS CYS A . n 
A 1 185 SER 185 215 215 SER SER A . n 
A 1 186 GLY 186 216 216 GLY GLY A . n 
A 1 187 THR 187 217 217 THR THR A . n 
A 1 188 GLY 188 218 218 GLY GLY A . n 
A 1 189 TYR 189 219 219 TYR TYR A . n 
A 1 190 VAL 190 220 220 VAL VAL A . n 
A 1 191 PHE 191 221 221 PHE PHE A . n 
A 1 192 SER 192 222 222 SER SER A . n 
A 1 193 GLY 193 223 223 GLY GLY A . n 
A 1 194 ASP 194 224 224 ASP ASP A . n 
A 1 195 VAL 195 225 225 VAL VAL A . n 
A 1 196 ALA 196 226 226 ALA ALA A . n 
A 1 197 SER 197 227 227 SER SER A . n 
A 1 198 GLN 198 228 228 GLN GLN A . n 
A 1 199 VAL 199 229 229 VAL VAL A . n 
A 1 200 TYR 200 230 230 TYR TYR A . n 
A 1 201 ASN 201 231 231 ASN ASN A . n 
A 1 202 VAL 202 232 232 VAL VAL A . n 
A 1 203 SER 203 233 233 SER SER A . n 
A 1 204 LYS 204 234 234 LYS LYS A . n 
A 1 205 SER 205 235 235 SER SER A . n 
A 1 206 VAL 206 236 236 VAL VAL A . n 
A 1 207 PRO 207 237 237 PRO PRO A . n 
A 1 208 TYR 208 238 238 TYR TYR A . n 
A 1 209 ILE 209 239 239 ILE ILE A . n 
A 1 210 LYS 210 240 240 LYS LYS A . n 
A 1 211 LEU 211 241 241 LEU LEU A . n 
A 1 212 GLU 212 242 242 GLU GLU A . n 
A 1 213 ASP 213 243 243 ASP ASP A . n 
A 1 214 VAL 214 244 244 VAL VAL A . n 
A 1 215 PHE 215 245 245 PHE PHE A . n 
A 1 216 VAL 216 246 246 VAL VAL A . n 
A 1 217 GLY 217 247 247 GLY GLY A . n 
A 1 218 LEU 218 248 248 LEU LEU A . n 
A 1 219 CYS 219 249 249 CYS CYS A . n 
A 1 220 LEU 220 250 250 LEU LEU A . n 
A 1 221 GLU 221 251 251 GLU GLU A . n 
A 1 222 ARG 222 252 252 ARG ARG A . n 
A 1 223 LEU 223 253 253 LEU LEU A . n 
A 1 224 ASN 224 254 254 ASN ASN A . n 
A 1 225 ILE 225 255 255 ILE ILE A . n 
A 1 226 ARG 226 256 256 ARG ARG A . n 
A 1 227 LEU 227 257 257 LEU LEU A . n 
A 1 228 GLU 228 258 258 GLU GLU A . n 
A 1 229 GLU 229 259 259 GLU GLU A . n 
A 1 230 LEU 230 260 260 LEU LEU A . n 
A 1 231 HIS 231 261 261 HIS HIS A . n 
A 1 232 SER 232 262 262 SER SER A . n 
A 1 233 GLN 233 263 263 GLN GLN A . n 
A 1 234 PRO 234 264 264 PRO PRO A . n 
A 1 235 THR 235 265 265 THR THR A . n 
A 1 236 PHE 236 266 266 PHE PHE A . n 
A 1 237 PHE 237 267 267 PHE PHE A . n 
A 1 238 PRO 238 268 268 PRO PRO A . n 
A 1 239 GLY 239 269 269 GLY GLY A . n 
A 1 240 GLY 240 270 270 GLY GLY A . n 
A 1 241 LEU 241 271 271 LEU LEU A . n 
A 1 242 ARG 242 272 272 ARG ARG A . n 
A 1 243 PHE 243 273 273 PHE PHE A . n 
A 1 244 SER 244 274 274 SER SER A . n 
A 1 245 VAL 245 275 275 VAL VAL A . n 
A 1 246 CYS 246 276 276 CYS CYS A . n 
A 1 247 LEU 247 277 277 LEU LEU A . n 
A 1 248 PHE 248 278 278 PHE PHE A . n 
A 1 249 ARG 249 279 279 ARG ARG A . n 
A 1 250 ARG 250 280 280 ARG ARG A . n 
A 1 251 ILE 251 281 281 ILE ILE A . n 
A 1 252 VAL 252 282 282 VAL VAL A . n 
A 1 253 ALA 253 283 283 ALA ALA A . n 
A 1 254 CYS 254 284 284 CYS CYS A . n 
A 1 255 HIS 255 285 285 HIS HIS A . n 
A 1 256 PHE 256 286 286 PHE PHE A . n 
A 1 257 ILE 257 287 287 ILE ILE A . n 
A 1 258 LYS 258 288 288 LYS LYS A . n 
A 1 259 PRO 259 289 289 PRO PRO A . n 
A 1 260 ARG 260 290 290 ARG ARG A . n 
A 1 261 THR 261 291 291 THR THR A . n 
A 1 262 LEU 262 292 292 LEU LEU A . n 
A 1 263 LEU 263 293 293 LEU LEU A . n 
A 1 264 ASP 264 294 294 ASP ASP A . n 
A 1 265 TYR 265 295 295 TYR TYR A . n 
A 1 266 TRP 266 296 296 TRP TRP A . n 
A 1 267 GLN 267 297 297 GLN GLN A . n 
A 1 268 ALA 268 298 298 ALA ALA A . n 
A 1 269 LEU 269 299 299 LEU LEU A . n 
A 1 270 GLU 270 300 300 GLU GLU A . n 
A 1 271 ASN 271 301 301 ASN ASN A . n 
A 1 272 SER 272 302 302 SER SER A . n 
A 1 273 ARG 273 303 303 ARG ARG A . n 
A 1 274 GLY 274 304 304 GLY GLY A . n 
A 1 275 GLU 275 305 305 GLU GLU A . n 
A 1 276 ASP 276 306 306 ASP ASP A . n 
A 1 277 CYS 277 307 307 CYS CYS A . n 
A 1 278 PRO 278 308 308 PRO PRO A . n 
B 1 1   PHE 1   31  ?   ?   ?   B . n 
B 1 2   LYS 2   32  ?   ?   ?   B . n 
B 1 3   GLU 3   33  ?   ?   ?   B . n 
B 1 4   GLN 4   34  ?   ?   ?   B . n 
B 1 5   SER 5   35  ?   ?   ?   B . n 
B 1 6   PHE 6   36  ?   ?   ?   B . n 
B 1 7   VAL 7   37  ?   ?   ?   B . n 
B 1 8   TYR 8   38  ?   ?   ?   B . n 
B 1 9   LYS 9   39  ?   ?   ?   B . n 
B 1 10  LYS 10  40  ?   ?   ?   B . n 
B 1 11  ASP 11  41  ?   ?   ?   B . n 
B 1 12  GLY 12  42  ?   ?   ?   B . n 
B 1 13  ASN 13  43  43  ASN ASN B . n 
B 1 14  PHE 14  44  44  PHE PHE B . n 
B 1 15  LEU 15  45  45  LEU LEU B . n 
B 1 16  LYS 16  46  46  LYS LYS B . n 
B 1 17  LEU 17  47  47  LEU LEU B . n 
B 1 18  PRO 18  48  48  PRO PRO B . n 
B 1 19  ASP 19  49  49  ASP ASP B . n 
B 1 20  THR 20  50  50  THR THR B . n 
B 1 21  ASP 21  51  51  ASP ASP B . n 
B 1 22  CYS 22  52  52  CYS CYS B . n 
B 1 23  ARG 23  53  53  ARG ARG B . n 
B 1 24  GLN 24  54  54  GLN GLN B . n 
B 1 25  THR 25  55  55  THR THR B . n 
B 1 26  PRO 26  56  56  PRO PRO B . n 
B 1 27  PRO 27  57  57  PRO PRO B . n 
B 1 28  PHE 28  58  58  PHE PHE B . n 
B 1 29  LEU 29  59  59  LEU LEU B . n 
B 1 30  VAL 30  60  60  VAL VAL B . n 
B 1 31  LEU 31  61  61  LEU LEU B . n 
B 1 32  LEU 32  62  62  LEU LEU B . n 
B 1 33  VAL 33  63  63  VAL VAL B . n 
B 1 34  THR 34  64  64  THR THR B . n 
B 1 35  SER 35  65  65  SER SER B . n 
B 1 36  SER 36  66  66  SER SER B . n 
B 1 37  HIS 37  67  67  HIS HIS B . n 
B 1 38  LYS 38  68  68  LYS LYS B . n 
B 1 39  GLN 39  69  69  GLN GLN B . n 
B 1 40  LEU 40  70  70  LEU LEU B . n 
B 1 41  ALA 41  71  71  ALA ALA B . n 
B 1 42  GLU 42  72  72  GLU GLU B . n 
B 1 43  ARG 43  73  73  ARG ARG B . n 
B 1 44  MET 44  74  74  MET MET B . n 
B 1 45  ALA 45  75  75  ALA ALA B . n 
B 1 46  ILE 46  76  76  ILE ILE B . n 
B 1 47  ARG 47  77  77  ARG ARG B . n 
B 1 48  GLN 48  78  78  GLN GLN B . n 
B 1 49  THR 49  79  79  THR THR B . n 
B 1 50  TRP 50  80  80  TRP TRP B . n 
B 1 51  GLY 51  81  81  GLY GLY B . n 
B 1 52  LYS 52  82  82  LYS LYS B . n 
B 1 53  GLU 53  83  83  GLU GLU B . n 
B 1 54  ARG 54  84  84  ARG ARG B . n 
B 1 55  MET 55  85  85  MET MET B . n 
B 1 56  VAL 56  86  86  VAL VAL B . n 
B 1 57  LYS 57  87  87  LYS LYS B . n 
B 1 58  GLY 58  88  88  GLY GLY B . n 
B 1 59  LYS 59  89  89  LYS LYS B . n 
B 1 60  GLN 60  90  90  GLN GLN B . n 
B 1 61  LEU 61  91  91  LEU LEU B . n 
B 1 62  LYS 62  92  92  LYS LYS B . n 
B 1 63  THR 63  93  93  THR THR B . n 
B 1 64  PHE 64  94  94  PHE PHE B . n 
B 1 65  PHE 65  95  95  PHE PHE B . n 
B 1 66  LEU 66  96  96  LEU LEU B . n 
B 1 67  LEU 67  97  97  LEU LEU B . n 
B 1 68  GLY 68  98  98  GLY GLY B . n 
B 1 69  THR 69  99  99  THR THR B . n 
B 1 70  THR 70  100 100 THR THR B . n 
B 1 71  SER 71  101 101 SER SER B . n 
B 1 72  SER 72  102 102 SER SER B . n 
B 1 73  ALA 73  103 103 ALA ALA B . n 
B 1 74  ALA 74  104 104 ALA ALA B . n 
B 1 75  GLU 75  105 105 GLU GLU B . n 
B 1 76  THR 76  106 106 THR THR B . n 
B 1 77  LYS 77  107 107 LYS LYS B . n 
B 1 78  GLU 78  108 108 GLU GLU B . n 
B 1 79  VAL 79  109 109 VAL VAL B . n 
B 1 80  ASP 80  110 110 ASP ASP B . n 
B 1 81  GLN 81  111 111 GLN GLN B . n 
B 1 82  GLU 82  112 112 GLU GLU B . n 
B 1 83  SER 83  113 113 SER SER B . n 
B 1 84  GLN 84  114 114 GLN GLN B . n 
B 1 85  ARG 85  115 115 ARG ARG B . n 
B 1 86  HIS 86  116 116 HIS HIS B . n 
B 1 87  GLY 87  117 117 GLY GLY B . n 
B 1 88  ASP 88  118 118 ASP ASP B . n 
B 1 89  ILE 89  119 119 ILE ILE B . n 
B 1 90  ILE 90  120 120 ILE ILE B . n 
B 1 91  GLN 91  121 121 GLN GLN B . n 
B 1 92  LYS 92  122 122 LYS LYS B . n 
B 1 93  ASP 93  123 123 ASP ASP B . n 
B 1 94  PHE 94  124 124 PHE PHE B . n 
B 1 95  LEU 95  125 125 LEU LEU B . n 
B 1 96  ASP 96  126 126 ASP ASP B . n 
B 1 97  VAL 97  127 127 VAL VAL B . n 
B 1 98  TYR 98  128 128 TYR TYR B . n 
B 1 99  TYR 99  129 129 TYR TYR B . n 
B 1 100 ASN 100 130 130 ASN ASN B . n 
B 1 101 LEU 101 131 131 LEU LEU B . n 
B 1 102 THR 102 132 132 THR THR B . n 
B 1 103 LEU 103 133 133 LEU LEU B . n 
B 1 104 LYS 104 134 134 LYS LYS B . n 
B 1 105 THR 105 135 135 THR THR B . n 
B 1 106 MET 106 136 136 MET MET B . n 
B 1 107 MET 107 137 137 MET MET B . n 
B 1 108 GLY 108 138 138 GLY GLY B . n 
B 1 109 ILE 109 139 139 ILE ILE B . n 
B 1 110 GLU 110 140 140 GLU GLU B . n 
B 1 111 TRP 111 141 141 TRP TRP B . n 
B 1 112 VAL 112 142 142 VAL VAL B . n 
B 1 113 HIS 113 143 143 HIS HIS B . n 
B 1 114 ARG 114 144 144 ARG ARG B . n 
B 1 115 PHE 115 145 145 PHE PHE B . n 
B 1 116 CYS 116 146 146 CYS CYS B . n 
B 1 117 PRO 117 147 147 PRO PRO B . n 
B 1 118 GLN 118 148 148 GLN GLN B . n 
B 1 119 ALA 119 149 149 ALA ALA B . n 
B 1 120 ALA 120 150 150 ALA ALA B . n 
B 1 121 PHE 121 151 151 PHE PHE B . n 
B 1 122 VAL 122 152 152 VAL VAL B . n 
B 1 123 MET 123 153 153 MET MET B . n 
B 1 124 LYS 124 154 154 LYS LYS B . n 
B 1 125 THR 125 155 155 THR THR B . n 
B 1 126 ASP 126 156 156 ASP ASP B . n 
B 1 127 SER 127 157 157 SER SER B . n 
B 1 128 ASP 128 158 158 ASP ASP B . n 
B 1 129 MET 129 159 159 MET MET B . n 
B 1 130 PHE 130 160 160 PHE PHE B . n 
B 1 131 ILE 131 161 161 ILE ILE B . n 
B 1 132 ASN 132 162 162 ASN ASN B . n 
B 1 133 VAL 133 163 163 VAL VAL B . n 
B 1 134 ASP 134 164 164 ASP ASP B . n 
B 1 135 TYR 135 165 165 TYR TYR B . n 
B 1 136 LEU 136 166 166 LEU LEU B . n 
B 1 137 THR 137 167 167 THR THR B . n 
B 1 138 GLU 138 168 168 GLU GLU B . n 
B 1 139 LEU 139 169 169 LEU LEU B . n 
B 1 140 LEU 140 170 170 LEU LEU B . n 
B 1 141 LEU 141 171 171 LEU LEU B . n 
B 1 142 LYS 142 172 172 LYS LYS B . n 
B 1 143 LYS 143 173 173 LYS LYS B . n 
B 1 144 ASN 144 174 174 ASN ASN B . n 
B 1 145 ARG 145 175 175 ARG ARG B . n 
B 1 146 THR 146 176 176 THR THR B . n 
B 1 147 THR 147 177 177 THR THR B . n 
B 1 148 ARG 148 178 178 ARG ARG B . n 
B 1 149 PHE 149 179 179 PHE PHE B . n 
B 1 150 PHE 150 180 180 PHE PHE B . n 
B 1 151 THR 151 181 181 THR THR B . n 
B 1 152 GLY 152 182 182 GLY GLY B . n 
B 1 153 PHE 153 183 183 PHE PHE B . n 
B 1 154 LEU 154 184 184 LEU LEU B . n 
B 1 155 LYS 155 185 185 LYS LYS B . n 
B 1 156 LEU 156 186 186 LEU LEU B . n 
B 1 157 ASN 157 187 187 ASN ASN B . n 
B 1 158 GLU 158 188 188 GLU GLU B . n 
B 1 159 PHE 159 189 189 PHE PHE B . n 
B 1 160 PRO 160 190 190 PRO PRO B . n 
B 1 161 ILE 161 191 191 ILE ILE B . n 
B 1 162 ARG 162 192 192 ARG ARG B . n 
B 1 163 GLN 163 193 193 GLN GLN B . n 
B 1 164 PRO 164 194 194 PRO PRO B . n 
B 1 165 PHE 165 195 195 PHE PHE B . n 
B 1 166 SER 166 196 196 SER SER B . n 
B 1 167 LYS 167 197 197 LYS LYS B . n 
B 1 168 TRP 168 198 198 TRP TRP B . n 
B 1 169 PHE 169 199 199 PHE PHE B . n 
B 1 170 VAL 170 200 200 VAL VAL B . n 
B 1 171 SER 171 201 201 SER SER B . n 
B 1 172 LYS 172 202 202 LYS LYS B . n 
B 1 173 SER 173 203 203 SER SER B . n 
B 1 174 GLU 174 204 204 GLU GLU B . n 
B 1 175 TYR 175 205 205 TYR TYR B . n 
B 1 176 PRO 176 206 206 PRO PRO B . n 
B 1 177 TRP 177 207 207 TRP TRP B . n 
B 1 178 ASP 178 208 208 ASP ASP B . n 
B 1 179 ARG 179 209 209 ARG ARG B . n 
B 1 180 TYR 180 210 210 TYR TYR B . n 
B 1 181 PRO 181 211 211 PRO PRO B . n 
B 1 182 PRO 182 212 212 PRO PRO B . n 
B 1 183 PHE 183 213 213 PHE PHE B . n 
B 1 184 CYS 184 214 214 CYS CYS B . n 
B 1 185 SER 185 215 215 SER SER B . n 
B 1 186 GLY 186 216 216 GLY GLY B . n 
B 1 187 THR 187 217 217 THR THR B . n 
B 1 188 GLY 188 218 218 GLY GLY B . n 
B 1 189 TYR 189 219 219 TYR TYR B . n 
B 1 190 VAL 190 220 220 VAL VAL B . n 
B 1 191 PHE 191 221 221 PHE PHE B . n 
B 1 192 SER 192 222 222 SER SER B . n 
B 1 193 GLY 193 223 223 GLY GLY B . n 
B 1 194 ASP 194 224 224 ASP ASP B . n 
B 1 195 VAL 195 225 225 VAL VAL B . n 
B 1 196 ALA 196 226 226 ALA ALA B . n 
B 1 197 SER 197 227 227 SER SER B . n 
B 1 198 GLN 198 228 228 GLN GLN B . n 
B 1 199 VAL 199 229 229 VAL VAL B . n 
B 1 200 TYR 200 230 230 TYR TYR B . n 
B 1 201 ASN 201 231 231 ASN ASN B . n 
B 1 202 VAL 202 232 232 VAL VAL B . n 
B 1 203 SER 203 233 233 SER SER B . n 
B 1 204 LYS 204 234 234 LYS LYS B . n 
B 1 205 SER 205 235 235 SER SER B . n 
B 1 206 VAL 206 236 236 VAL VAL B . n 
B 1 207 PRO 207 237 237 PRO PRO B . n 
B 1 208 TYR 208 238 238 TYR TYR B . n 
B 1 209 ILE 209 239 239 ILE ILE B . n 
B 1 210 LYS 210 240 240 LYS LYS B . n 
B 1 211 LEU 211 241 241 LEU LEU B . n 
B 1 212 GLU 212 242 242 GLU GLU B . n 
B 1 213 ASP 213 243 243 ASP ASP B . n 
B 1 214 VAL 214 244 244 VAL VAL B . n 
B 1 215 PHE 215 245 245 PHE PHE B . n 
B 1 216 VAL 216 246 246 VAL VAL B . n 
B 1 217 GLY 217 247 247 GLY GLY B . n 
B 1 218 LEU 218 248 248 LEU LEU B . n 
B 1 219 CYS 219 249 249 CYS CYS B . n 
B 1 220 LEU 220 250 250 LEU LEU B . n 
B 1 221 GLU 221 251 251 GLU GLU B . n 
B 1 222 ARG 222 252 252 ARG ARG B . n 
B 1 223 LEU 223 253 253 LEU LEU B . n 
B 1 224 ASN 224 254 254 ASN ASN B . n 
B 1 225 ILE 225 255 255 ILE ILE B . n 
B 1 226 ARG 226 256 256 ARG ARG B . n 
B 1 227 LEU 227 257 257 LEU LEU B . n 
B 1 228 GLU 228 258 258 GLU GLU B . n 
B 1 229 GLU 229 259 259 GLU GLU B . n 
B 1 230 LEU 230 260 260 LEU LEU B . n 
B 1 231 HIS 231 261 261 HIS HIS B . n 
B 1 232 SER 232 262 262 SER SER B . n 
B 1 233 GLN 233 263 263 GLN GLN B . n 
B 1 234 PRO 234 264 264 PRO PRO B . n 
B 1 235 THR 235 265 265 THR THR B . n 
B 1 236 PHE 236 266 266 PHE PHE B . n 
B 1 237 PHE 237 267 267 PHE PHE B . n 
B 1 238 PRO 238 268 268 PRO PRO B . n 
B 1 239 GLY 239 269 269 GLY GLY B . n 
B 1 240 GLY 240 270 270 GLY GLY B . n 
B 1 241 LEU 241 271 271 LEU LEU B . n 
B 1 242 ARG 242 272 272 ARG ARG B . n 
B 1 243 PHE 243 273 273 PHE PHE B . n 
B 1 244 SER 244 274 274 SER SER B . n 
B 1 245 VAL 245 275 275 VAL VAL B . n 
B 1 246 CYS 246 276 276 CYS CYS B . n 
B 1 247 LEU 247 277 277 LEU LEU B . n 
B 1 248 PHE 248 278 278 PHE PHE B . n 
B 1 249 ARG 249 279 279 ARG ARG B . n 
B 1 250 ARG 250 280 280 ARG ARG B . n 
B 1 251 ILE 251 281 281 ILE ILE B . n 
B 1 252 VAL 252 282 282 VAL VAL B . n 
B 1 253 ALA 253 283 283 ALA ALA B . n 
B 1 254 CYS 254 284 284 CYS CYS B . n 
B 1 255 HIS 255 285 285 HIS HIS B . n 
B 1 256 PHE 256 286 286 PHE PHE B . n 
B 1 257 ILE 257 287 287 ILE ILE B . n 
B 1 258 LYS 258 288 288 LYS LYS B . n 
B 1 259 PRO 259 289 289 PRO PRO B . n 
B 1 260 ARG 260 290 290 ARG ARG B . n 
B 1 261 THR 261 291 291 THR THR B . n 
B 1 262 LEU 262 292 292 LEU LEU B . n 
B 1 263 LEU 263 293 293 LEU LEU B . n 
B 1 264 ASP 264 294 294 ASP ASP B . n 
B 1 265 TYR 265 295 295 TYR TYR B . n 
B 1 266 TRP 266 296 296 TRP TRP B . n 
B 1 267 GLN 267 297 297 GLN GLN B . n 
B 1 268 ALA 268 298 298 ALA ALA B . n 
B 1 269 LEU 269 299 299 LEU LEU B . n 
B 1 270 GLU 270 300 300 GLU GLU B . n 
B 1 271 ASN 271 301 301 ASN ASN B . n 
B 1 272 SER 272 302 302 SER SER B . n 
B 1 273 ARG 273 303 303 ARG ARG B . n 
B 1 274 GLY 274 304 304 GLY GLY B . n 
B 1 275 GLU 275 305 305 GLU GLU B . n 
B 1 276 ASP 276 306 306 ASP ASP B . n 
B 1 277 CYS 277 307 307 CYS CYS B . n 
B 1 278 PRO 278 308 308 PRO PRO B . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 2 BGC 1 C BGC 1 A BGC 316 n 
C 2 GAL 2 C GAL 2 A GAL 315 n 
C 2 GLA 3 C GLA 3 A GLA 314 n 
C 2 NGA 4 C NGA 4 A NGA 313 n 
D 2 BGC 1 D BGC 1 B BGC 316 n 
D 2 GAL 2 D GAL 2 B GAL 315 n 
D 2 GLA 3 D GLA 3 B GLA 314 n 
D 2 NGA 4 D NGA 4 B NGA 313 n 
E 3 NAG 1 E NAG 1 E NAG 1   n 
E 3 NAG 2 E NAG 2 E NAG 2   n 
F 4 NAG 1 F NAG 1 F NAG 2   n 
F 4 NAG 2 F NAG 2 F NAG 1   n 
F 4 FUC 3 F FUC 3 F FUC 3   n 
G 3 NAG 1 G NAG 1 G NAG 1   n 
G 3 NAG 2 G NAG 2 G NAG 2   n 
H 5 NAG 1 H NAG 1 H NAG 1   n 
H 5 NAG 2 H NAG 2 H NAG 2   n 
H 5 BMA 3 H BMA 3 H BMA 3   n 
H 5 MAN 4 H MAN 4 H MAN 4   n 
H 5 MAN 5 H MAN 5 H MAN 5   n 
H 5 FUC 6 H FUC 6 H FUC 6   n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 BGC ? ? BGC ? ? 'SUBJECT OF INVESTIGATION' ? 
2 GAL ? ? GAL ? ? 'SUBJECT OF INVESTIGATION' ? 
3 GLA ? ? GLA ? ? 'SUBJECT OF INVESTIGATION' ? 
4 NGA ? ? NGA ? ? 'SUBJECT OF INVESTIGATION' ? 
5 UDP ? ? UDP ? ? 'SUBJECT OF INVESTIGATION' ? 
6 MN  ? ? MN  ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
I 6  MN  1   401 310 MN  MN  A . 
J 7  UDP 1   402 311 UDP UDP A . 
K 8  B3P 1   403 312 B3P BIS A . 
L 6  MN  1   401 310 MN  MN  B . 
M 7  UDP 1   402 311 UDP UDP B . 
N 8  B3P 1   403 312 B3P BIS B . 
O 9  NAG 1   404 1   NAG NAG B . 
P 10 HOH 1   501 49  HOH HOH A . 
P 10 HOH 2   502 85  HOH HOH A . 
P 10 HOH 3   503 100 HOH HOH A . 
P 10 HOH 4   504 148 HOH HOH A . 
P 10 HOH 5   505 43  HOH HOH A . 
P 10 HOH 6   506 233 HOH HOH A . 
P 10 HOH 7   507 41  HOH HOH A . 
P 10 HOH 8   508 231 HOH HOH A . 
P 10 HOH 9   509 229 HOH HOH A . 
P 10 HOH 10  510 238 HOH HOH A . 
P 10 HOH 11  511 121 HOH HOH A . 
P 10 HOH 12  512 177 HOH HOH A . 
P 10 HOH 13  513 170 HOH HOH A . 
P 10 HOH 14  514 45  HOH HOH A . 
P 10 HOH 15  515 209 HOH HOH A . 
P 10 HOH 16  516 221 HOH HOH A . 
P 10 HOH 17  517 94  HOH HOH A . 
P 10 HOH 18  518 144 HOH HOH A . 
P 10 HOH 19  519 139 HOH HOH A . 
P 10 HOH 20  520 1   HOH HOH A . 
P 10 HOH 21  521 147 HOH HOH A . 
P 10 HOH 22  522 65  HOH HOH A . 
P 10 HOH 23  523 53  HOH HOH A . 
P 10 HOH 24  524 24  HOH HOH A . 
P 10 HOH 25  525 37  HOH HOH A . 
P 10 HOH 26  526 239 HOH HOH A . 
P 10 HOH 27  527 61  HOH HOH A . 
P 10 HOH 28  528 55  HOH HOH A . 
P 10 HOH 29  529 108 HOH HOH A . 
P 10 HOH 30  530 4   HOH HOH A . 
P 10 HOH 31  531 51  HOH HOH A . 
P 10 HOH 32  532 2   HOH HOH A . 
P 10 HOH 33  533 131 HOH HOH A . 
P 10 HOH 34  534 208 HOH HOH A . 
P 10 HOH 35  535 87  HOH HOH A . 
P 10 HOH 36  536 119 HOH HOH A . 
P 10 HOH 37  537 88  HOH HOH A . 
P 10 HOH 38  538 10  HOH HOH A . 
P 10 HOH 39  539 12  HOH HOH A . 
P 10 HOH 40  540 161 HOH HOH A . 
P 10 HOH 41  541 163 HOH HOH A . 
P 10 HOH 42  542 146 HOH HOH A . 
P 10 HOH 43  543 270 HOH HOH A . 
P 10 HOH 44  544 214 HOH HOH A . 
P 10 HOH 45  545 36  HOH HOH A . 
P 10 HOH 46  546 235 HOH HOH A . 
P 10 HOH 47  547 81  HOH HOH A . 
P 10 HOH 48  548 236 HOH HOH A . 
P 10 HOH 49  549 46  HOH HOH A . 
P 10 HOH 50  550 135 HOH HOH A . 
P 10 HOH 51  551 35  HOH HOH A . 
P 10 HOH 52  552 19  HOH HOH A . 
P 10 HOH 53  553 5   HOH HOH A . 
P 10 HOH 54  554 31  HOH HOH A . 
P 10 HOH 55  555 62  HOH HOH A . 
P 10 HOH 56  556 166 HOH HOH A . 
P 10 HOH 57  557 222 HOH HOH A . 
P 10 HOH 58  558 23  HOH HOH A . 
P 10 HOH 59  559 202 HOH HOH A . 
P 10 HOH 60  560 56  HOH HOH A . 
P 10 HOH 61  561 20  HOH HOH A . 
P 10 HOH 62  562 48  HOH HOH A . 
P 10 HOH 63  563 288 HOH HOH A . 
P 10 HOH 64  564 154 HOH HOH A . 
P 10 HOH 65  565 181 HOH HOH A . 
P 10 HOH 66  566 89  HOH HOH A . 
P 10 HOH 67  567 3   HOH HOH A . 
P 10 HOH 68  568 16  HOH HOH A . 
P 10 HOH 69  569 57  HOH HOH A . 
P 10 HOH 70  570 11  HOH HOH A . 
P 10 HOH 71  571 115 HOH HOH A . 
P 10 HOH 72  572 74  HOH HOH A . 
P 10 HOH 73  573 9   HOH HOH A . 
P 10 HOH 74  574 66  HOH HOH A . 
P 10 HOH 75  575 293 HOH HOH A . 
P 10 HOH 76  576 96  HOH HOH A . 
P 10 HOH 77  577 28  HOH HOH A . 
P 10 HOH 78  578 251 HOH HOH A . 
P 10 HOH 79  579 60  HOH HOH A . 
P 10 HOH 80  580 106 HOH HOH A . 
P 10 HOH 81  581 99  HOH HOH A . 
P 10 HOH 82  582 38  HOH HOH A . 
P 10 HOH 83  583 104 HOH HOH A . 
P 10 HOH 84  584 268 HOH HOH A . 
P 10 HOH 85  585 117 HOH HOH A . 
P 10 HOH 86  586 153 HOH HOH A . 
P 10 HOH 87  587 18  HOH HOH A . 
P 10 HOH 88  588 54  HOH HOH A . 
P 10 HOH 89  589 241 HOH HOH A . 
P 10 HOH 90  590 22  HOH HOH A . 
P 10 HOH 91  591 164 HOH HOH A . 
P 10 HOH 92  592 26  HOH HOH A . 
P 10 HOH 93  593 95  HOH HOH A . 
P 10 HOH 94  594 234 HOH HOH A . 
P 10 HOH 95  595 8   HOH HOH A . 
P 10 HOH 96  596 78  HOH HOH A . 
P 10 HOH 97  597 157 HOH HOH A . 
P 10 HOH 98  598 68  HOH HOH A . 
P 10 HOH 99  599 105 HOH HOH A . 
P 10 HOH 100 600 167 HOH HOH A . 
P 10 HOH 101 601 86  HOH HOH A . 
P 10 HOH 102 602 72  HOH HOH A . 
P 10 HOH 103 603 42  HOH HOH A . 
P 10 HOH 104 604 59  HOH HOH A . 
P 10 HOH 105 605 15  HOH HOH A . 
P 10 HOH 106 606 107 HOH HOH A . 
P 10 HOH 107 607 40  HOH HOH A . 
P 10 HOH 108 608 21  HOH HOH A . 
P 10 HOH 109 609 155 HOH HOH A . 
P 10 HOH 110 610 172 HOH HOH A . 
P 10 HOH 111 611 240 HOH HOH A . 
P 10 HOH 112 612 291 HOH HOH A . 
P 10 HOH 113 613 90  HOH HOH A . 
P 10 HOH 114 614 285 HOH HOH A . 
P 10 HOH 115 615 76  HOH HOH A . 
P 10 HOH 116 616 138 HOH HOH A . 
P 10 HOH 117 617 30  HOH HOH A . 
P 10 HOH 118 618 70  HOH HOH A . 
P 10 HOH 119 619 287 HOH HOH A . 
P 10 HOH 120 620 7   HOH HOH A . 
P 10 HOH 121 621 44  HOH HOH A . 
P 10 HOH 122 622 25  HOH HOH A . 
P 10 HOH 123 623 190 HOH HOH A . 
P 10 HOH 124 624 129 HOH HOH A . 
P 10 HOH 125 625 80  HOH HOH A . 
P 10 HOH 126 626 39  HOH HOH A . 
P 10 HOH 127 627 29  HOH HOH A . 
P 10 HOH 128 628 32  HOH HOH A . 
P 10 HOH 129 629 67  HOH HOH A . 
P 10 HOH 130 630 159 HOH HOH A . 
P 10 HOH 131 631 14  HOH HOH A . 
P 10 HOH 132 632 110 HOH HOH A . 
P 10 HOH 133 633 232 HOH HOH A . 
P 10 HOH 134 634 97  HOH HOH A . 
P 10 HOH 135 635 136 HOH HOH A . 
P 10 HOH 136 636 112 HOH HOH A . 
P 10 HOH 137 637 69  HOH HOH A . 
P 10 HOH 138 638 13  HOH HOH A . 
P 10 HOH 139 639 277 HOH HOH A . 
P 10 HOH 140 640 201 HOH HOH A . 
P 10 HOH 141 641 6   HOH HOH A . 
P 10 HOH 142 642 290 HOH HOH A . 
P 10 HOH 143 643 75  HOH HOH A . 
P 10 HOH 144 644 200 HOH HOH A . 
P 10 HOH 145 645 252 HOH HOH A . 
P 10 HOH 146 646 204 HOH HOH A . 
P 10 HOH 147 647 223 HOH HOH A . 
P 10 HOH 148 648 253 HOH HOH A . 
P 10 HOH 149 649 103 HOH HOH A . 
P 10 HOH 150 650 217 HOH HOH A . 
P 10 HOH 151 651 189 HOH HOH A . 
P 10 HOH 152 652 274 HOH HOH A . 
P 10 HOH 153 653 150 HOH HOH A . 
P 10 HOH 154 654 260 HOH HOH A . 
P 10 HOH 155 655 175 HOH HOH A . 
P 10 HOH 156 656 275 HOH HOH A . 
P 10 HOH 157 657 145 HOH HOH A . 
P 10 HOH 158 658 215 HOH HOH A . 
P 10 HOH 159 659 281 HOH HOH A . 
P 10 HOH 160 660 218 HOH HOH A . 
P 10 HOH 161 661 228 HOH HOH A . 
P 10 HOH 162 662 206 HOH HOH A . 
P 10 HOH 163 663 191 HOH HOH A . 
P 10 HOH 164 664 125 HOH HOH A . 
P 10 HOH 165 665 255 HOH HOH A . 
P 10 HOH 166 666 242 HOH HOH A . 
P 10 HOH 167 667 141 HOH HOH A . 
P 10 HOH 168 668 249 HOH HOH A . 
P 10 HOH 169 669 216 HOH HOH A . 
P 10 HOH 170 670 247 HOH HOH A . 
P 10 HOH 171 671 230 HOH HOH A . 
P 10 HOH 172 672 272 HOH HOH A . 
P 10 HOH 173 673 142 HOH HOH A . 
P 10 HOH 174 674 257 HOH HOH A . 
P 10 HOH 175 675 130 HOH HOH A . 
P 10 HOH 176 676 187 HOH HOH A . 
P 10 HOH 177 677 258 HOH HOH A . 
P 10 HOH 178 678 47  HOH HOH A . 
P 10 HOH 179 679 256 HOH HOH A . 
P 10 HOH 180 680 140 HOH HOH A . 
P 10 HOH 181 681 248 HOH HOH A . 
P 10 HOH 182 682 276 HOH HOH A . 
P 10 HOH 183 683 196 HOH HOH A . 
P 10 HOH 184 684 171 HOH HOH A . 
P 10 HOH 185 685 237 HOH HOH A . 
P 10 HOH 186 686 219 HOH HOH A . 
P 10 HOH 187 687 198 HOH HOH A . 
P 10 HOH 188 688 186 HOH HOH A . 
P 10 HOH 189 689 124 HOH HOH A . 
P 10 HOH 190 690 220 HOH HOH A . 
P 10 HOH 191 691 92  HOH HOH A . 
P 10 HOH 192 692 27  HOH HOH A . 
P 10 HOH 193 693 250 HOH HOH A . 
P 10 HOH 194 694 286 HOH HOH A . 
P 10 HOH 195 695 283 HOH HOH A . 
P 10 HOH 196 696 133 HOH HOH A . 
P 10 HOH 197 697 152 HOH HOH A . 
P 10 HOH 198 698 273 HOH HOH A . 
P 10 HOH 199 699 178 HOH HOH A . 
P 10 HOH 200 700 173 HOH HOH A . 
P 10 HOH 201 701 162 HOH HOH A . 
P 10 HOH 202 702 113 HOH HOH A . 
P 10 HOH 203 703 98  HOH HOH A . 
P 10 HOH 204 704 134 HOH HOH A . 
P 10 HOH 205 705 197 HOH HOH A . 
P 10 HOH 206 706 33  HOH HOH A . 
P 10 HOH 207 707 188 HOH HOH A . 
P 10 HOH 208 708 254 HOH HOH A . 
P 10 HOH 209 709 289 HOH HOH A . 
P 10 HOH 210 710 17  HOH HOH A . 
P 10 HOH 211 711 271 HOH HOH A . 
P 10 HOH 212 712 192 HOH HOH A . 
P 10 HOH 213 713 160 HOH HOH A . 
P 10 HOH 214 714 284 HOH HOH A . 
P 10 HOH 215 715 102 HOH HOH A . 
P 10 HOH 216 716 269 HOH HOH A . 
Q 10 HOH 1   501 199 HOH HOH B . 
Q 10 HOH 2   502 296 HOH HOH B . 
Q 10 HOH 3   503 292 HOH HOH B . 
Q 10 HOH 4   504 118 HOH HOH B . 
Q 10 HOH 5   505 126 HOH HOH B . 
Q 10 HOH 6   506 262 HOH HOH B . 
Q 10 HOH 7   507 143 HOH HOH B . 
Q 10 HOH 8   508 73  HOH HOH B . 
Q 10 HOH 9   509 207 HOH HOH B . 
Q 10 HOH 10  510 180 HOH HOH B . 
Q 10 HOH 11  511 179 HOH HOH B . 
Q 10 HOH 12  512 63  HOH HOH B . 
Q 10 HOH 13  513 151 HOH HOH B . 
Q 10 HOH 14  514 244 HOH HOH B . 
Q 10 HOH 15  515 64  HOH HOH B . 
Q 10 HOH 16  516 226 HOH HOH B . 
Q 10 HOH 17  517 58  HOH HOH B . 
Q 10 HOH 18  518 123 HOH HOH B . 
Q 10 HOH 19  519 52  HOH HOH B . 
Q 10 HOH 20  520 122 HOH HOH B . 
Q 10 HOH 21  521 185 HOH HOH B . 
Q 10 HOH 22  522 261 HOH HOH B . 
Q 10 HOH 23  523 193 HOH HOH B . 
Q 10 HOH 24  524 280 HOH HOH B . 
Q 10 HOH 25  525 194 HOH HOH B . 
Q 10 HOH 26  526 243 HOH HOH B . 
Q 10 HOH 27  527 168 HOH HOH B . 
Q 10 HOH 28  528 34  HOH HOH B . 
Q 10 HOH 29  529 137 HOH HOH B . 
Q 10 HOH 30  530 211 HOH HOH B . 
Q 10 HOH 31  531 77  HOH HOH B . 
Q 10 HOH 32  532 91  HOH HOH B . 
Q 10 HOH 33  533 282 HOH HOH B . 
Q 10 HOH 34  534 93  HOH HOH B . 
Q 10 HOH 35  535 210 HOH HOH B . 
Q 10 HOH 36  536 294 HOH HOH B . 
Q 10 HOH 37  537 195 HOH HOH B . 
Q 10 HOH 38  538 205 HOH HOH B . 
Q 10 HOH 39  539 165 HOH HOH B . 
Q 10 HOH 40  540 50  HOH HOH B . 
Q 10 HOH 41  541 263 HOH HOH B . 
Q 10 HOH 42  542 265 HOH HOH B . 
Q 10 HOH 43  543 82  HOH HOH B . 
Q 10 HOH 44  544 116 HOH HOH B . 
Q 10 HOH 45  545 267 HOH HOH B . 
Q 10 HOH 46  546 120 HOH HOH B . 
Q 10 HOH 47  547 156 HOH HOH B . 
Q 10 HOH 48  548 278 HOH HOH B . 
Q 10 HOH 49  549 101 HOH HOH B . 
Q 10 HOH 50  550 79  HOH HOH B . 
Q 10 HOH 51  551 169 HOH HOH B . 
Q 10 HOH 52  552 71  HOH HOH B . 
Q 10 HOH 53  553 182 HOH HOH B . 
Q 10 HOH 54  554 84  HOH HOH B . 
Q 10 HOH 55  555 111 HOH HOH B . 
Q 10 HOH 56  556 83  HOH HOH B . 
Q 10 HOH 57  557 132 HOH HOH B . 
Q 10 HOH 58  558 128 HOH HOH B . 
Q 10 HOH 59  559 174 HOH HOH B . 
Q 10 HOH 60  560 266 HOH HOH B . 
Q 10 HOH 61  561 225 HOH HOH B . 
Q 10 HOH 62  562 158 HOH HOH B . 
Q 10 HOH 63  563 203 HOH HOH B . 
Q 10 HOH 64  564 114 HOH HOH B . 
Q 10 HOH 65  565 259 HOH HOH B . 
Q 10 HOH 66  566 213 HOH HOH B . 
Q 10 HOH 67  567 227 HOH HOH B . 
Q 10 HOH 68  568 212 HOH HOH B . 
Q 10 HOH 69  569 245 HOH HOH B . 
Q 10 HOH 70  570 176 HOH HOH B . 
Q 10 HOH 71  571 224 HOH HOH B . 
Q 10 HOH 72  572 127 HOH HOH B . 
Q 10 HOH 73  573 279 HOH HOH B . 
Q 10 HOH 74  574 264 HOH HOH B . 
Q 10 HOH 75  575 183 HOH HOH B . 
Q 10 HOH 76  576 184 HOH HOH B . 
Q 10 HOH 77  577 246 HOH HOH B . 
Q 10 HOH 78  578 295 HOH HOH B . 
Q 10 HOH 79  579 149 HOH HOH B . 
Q 10 HOH 80  580 109 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 1 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? Blu-Ice  ? ? ? .           2 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   95.470 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZWP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     47.646 
_cell.length_a_esd                 ? 
_cell.length_b                     86.360 
_cell.length_b_esd                 ? 
_cell.length_c                     87.187 
_cell.length_c_esd                 ? 
_cell.volume                       357115.440 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZWP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZWP 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.74 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          55.16 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1M BIS-TRIS Propane pH8.5, 0.2M Potassium Sodium Tartrate, 20% w/v PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'RAYONIX MX300HE' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-12-02 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'NSRRC BEAMLINE BL15A1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL15A1 
_diffrn_source.pdbx_synchrotron_site       NSRRC 
# 
_reflns.B_iso_Wilson_estimate                          27.02 
_reflns.entry_id                                       8ZWP 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.86 
_reflns.d_resolution_low                               50.0 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     58604 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          21.95 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.067 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.86 
_reflns_shell.d_res_low                                     1.93 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.13 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             5703 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               5.4 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          97.7 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.724 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               42.16 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ZWP 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.86 
_refine.ls_d_res_low                             28.93 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     58561 
_refine.ls_number_reflns_R_free                  2983 
_refine.ls_number_reflns_R_work                  55578 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.36 
_refine.ls_percent_reflns_R_free                 5.09 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2005 
_refine.ls_R_factor_R_free                       0.2334 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1987 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 25.2358 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2228 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.86 
_refine_hist.d_res_low                        28.93 
_refine_hist.number_atoms_solvent             296 
_refine_hist.number_atoms_total               5043 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4382 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         365 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0069  ? 4879 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9471  ? 6614 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0584  ? 779  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0102  ? 789  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 15.0804 ? 1846 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.pdbx_ens_id 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.ncs_model_details 
1 'X-RAY DIFFRACTION' d_2 ens_1 0.770329728798 ? ? ? 'Torsion NCS' A A ? ? ? ? 
2 'X-RAY DIFFRACTION' d_2 ens_2 2.84763970855  ? ? ? 'Torsion NCS' E E ? ? ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.86 1.89  . . 131 2553 95.96  . . . . 0.2994 . . . . . . . . . . . 0.3237 
'X-RAY DIFFRACTION' 1.89 1.92  . . 136 2590 98.52  . . . . 0.2726 . . . . . . . . . . . 0.3149 
'X-RAY DIFFRACTION' 1.92 1.96  . . 135 2606 99.06  . . . . 0.2583 . . . . . . . . . . . 0.2547 
'X-RAY DIFFRACTION' 1.96 2.00  . . 132 2652 99.07  . . . . 0.2439 . . . . . . . . . . . 0.2892 
'X-RAY DIFFRACTION' 2.00 2.04  . . 135 2631 99.32  . . . . 0.2478 . . . . . . . . . . . 0.2735 
'X-RAY DIFFRACTION' 2.04 2.08  . . 145 2648 99.25  . . . . 0.2320 . . . . . . . . . . . 0.2445 
'X-RAY DIFFRACTION' 2.08 2.13  . . 124 2638 99.21  . . . . 0.2236 . . . . . . . . . . . 0.2680 
'X-RAY DIFFRACTION' 2.13 2.18  . . 132 2675 99.33  . . . . 0.2229 . . . . . . . . . . . 0.2449 
'X-RAY DIFFRACTION' 2.18 2.24  . . 158 2634 99.64  . . . . 0.2245 . . . . . . . . . . . 0.2671 
'X-RAY DIFFRACTION' 2.24 2.31  . . 146 2609 99.46  . . . . 0.2177 . . . . . . . . . . . 0.2741 
'X-RAY DIFFRACTION' 2.31 2.38  . . 163 2668 99.75  . . . . 0.2168 . . . . . . . . . . . 0.2686 
'X-RAY DIFFRACTION' 2.38 2.47  . . 129 2656 99.54  . . . . 0.2163 . . . . . . . . . . . 0.2571 
'X-RAY DIFFRACTION' 2.47 2.57  . . 144 2622 99.82  . . . . 0.2223 . . . . . . . . . . . 0.2520 
'X-RAY DIFFRACTION' 2.57 2.68  . . 177 2644 99.89  . . . . 0.2215 . . . . . . . . . . . 0.2551 
'X-RAY DIFFRACTION' 2.68 2.82  . . 128 2668 99.89  . . . . 0.2192 . . . . . . . . . . . 0.2850 
'X-RAY DIFFRACTION' 2.82 3.00  . . 114 2699 99.89  . . . . 0.2191 . . . . . . . . . . . 0.2766 
'X-RAY DIFFRACTION' 3.00 3.23  . . 163 2637 99.93  . . . . 0.2050 . . . . . . . . . . . 0.2735 
'X-RAY DIFFRACTION' 3.23 3.56  . . 145 2677 99.89  . . . . 0.2008 . . . . . . . . . . . 0.2414 
'X-RAY DIFFRACTION' 3.56 4.07  . . 168 2647 100.00 . . . . 0.1696 . . . . . . . . . . . 0.1793 
'X-RAY DIFFRACTION' 4.07 5.12  . . 169 2666 99.54  . . . . 0.1465 . . . . . . . . . . . 0.1838 
'X-RAY DIFFRACTION' 5.13 28.93 . . 109 2758 99.62  . . . . 0.1649 . . . . . . . . . . . 0.1886 
# 
loop_
_struct_ncs_oper.id 
_struct_ncs_oper.code 
_struct_ncs_oper.matrix[1][1] 
_struct_ncs_oper.matrix[1][2] 
_struct_ncs_oper.matrix[1][3] 
_struct_ncs_oper.matrix[2][1] 
_struct_ncs_oper.matrix[2][2] 
_struct_ncs_oper.matrix[2][3] 
_struct_ncs_oper.matrix[3][1] 
_struct_ncs_oper.matrix[3][2] 
_struct_ncs_oper.matrix[3][3] 
_struct_ncs_oper.vector[1] 
_struct_ncs_oper.vector[2] 
_struct_ncs_oper.vector[3] 
_struct_ncs_oper.details 
1 given 0.189324760627  0.0117769650148 -0.981843897017 -0.0247516598137 0.999667572662  0.00721799868782 0.981602511381  
0.0229357202553 0.189553323332  38.813959086  8.96138791516 -27.313599814 ? 
2 given -0.399401218097 0.767190683335  -0.501893536904 0.666640973394   -0.132771341891 -0.733458644617  -0.629339717143 
-0.627527072066 -0.458411708238 30.8136966675 27.0281785616 46.559491036  ? 
# 
loop_
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.id 
_struct_ncs_dom.details 
ens_1 d_1 
;(chain "A" and (resid 43 through 160 or resid 162 through 202 or resid 204 through 286 or resid 288 through 312 or resid 313 through 316))
;
ens_1 d_2 
;(chain "B" and (resid 43 through 160 or resid 162 through 202 or resid 204 through 286 or resid 288 through 312 or resid 313 through 316))
;
ens_2 d_1 
;chain "E"
;
ens_2 d_2 
;chain "G"
;
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
ens_1 d_1 1  A ASN 13  . A PHE 130 . A ASN 43  A PHE 160 ? ? 
ens_1 d_1 2  A ASN 132 . A LYS 172 . A ASN 162 A LYS 202 ? ? 
ens_1 d_1 3  A GLU 174 . A PHE 256 . A GLU 204 A PHE 286 ? ? 
ens_1 d_1 4  A LYS 258 . A PRO 278 . A LYS 288 A PRO 308 ? ? 
ens_1 d_1 5  I MN  .   . I MN  .   . A MN  401 A MN  401 ? ? 
ens_1 d_1 6  J UDP .   . J UDP .   . A UDP 402 A UDP 402 ? ? 
ens_1 d_1 7  K B3P .   . K B3P .   . A B3P 403 A B3P 403 ? ? 
ens_1 d_1 8  C NGA .   . C NGA .   . C NGA 4   C NGA 4   ? ? 
ens_1 d_1 9  C GLA .   . C GLA .   . C GLA 3   C GLA 3   ? ? 
ens_1 d_1 10 C GAL .   . C GAL .   . C GAL 2   C GAL 2   ? ? 
ens_1 d_1 11 C BGC .   . C BGC .   . C BGC 1   C BGC 1   ? ? 
ens_1 d_2 1  B ASN 13  . B PHE 130 . B ASN 43  B PHE 160 ? ? 
ens_1 d_2 2  B ASN 132 . B LYS 172 . B ASN 162 B LYS 202 ? ? 
ens_1 d_2 3  B GLU 174 . B PHE 256 . B GLU 204 B PHE 286 ? ? 
ens_1 d_2 4  B LYS 258 . B PRO 278 . B LYS 288 B PRO 308 ? ? 
ens_1 d_2 5  L MN  .   . L MN  .   . B MN  401 B MN  401 ? ? 
ens_1 d_2 6  M UDP .   . M UDP .   . B UDP 402 B UDP 402 ? ? 
ens_1 d_2 7  N B3P .   . N B3P .   . B B3P 403 B B3P 403 ? ? 
ens_1 d_2 8  D NGA .   . D NGA .   . D NGA 4   D NGA 4   ? ? 
ens_1 d_2 9  D GLA .   . D GLA .   . D GLA 3   D GLA 3   ? ? 
ens_1 d_2 10 D GAL .   . D GAL .   . D GAL 2   D GAL 2   ? ? 
ens_1 d_2 11 D BGC .   . D BGC .   . D BGC 1   D BGC 1   ? ? 
ens_2 d_1 1  E NAG .   . E NAG .   . E NAG 1   E NAG 1   ? ? 
ens_2 d_1 2  E NAG .   . E NAG .   . E NAG 2   E NAG 2   ? ? 
ens_2 d_2 1  G NAG .   . G NAG .   . G NAG 1   G NAG 1   ? ? 
ens_2 d_2 2  G NAG .   . G NAG .   . G NAG 2   G NAG 2   ? ? 
# 
loop_
_struct_ncs_ens.id 
_struct_ncs_ens.details 
ens_1 ? 
ens_2 ? 
# 
loop_
_struct_ncs_ens_gen.ens_id 
_struct_ncs_ens_gen.dom_id_1 
_struct_ncs_ens_gen.dom_id_2 
_struct_ncs_ens_gen.oper_id 
ens_1 d_2 d_1 1 
ens_2 d_2 d_1 2 
# 
_struct.entry_id                     8ZWP 
_struct.title                        'Structure-Based Mechanism and Specificity of Human Galactosyltransferase B3GalT5' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZWP 
_struct_keywords.text            'Gb4, globo-series biosynthesis, bi-bi mechanism, SN2-like reaction, ternary complex, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1  ? 
B N N 1  ? 
C N N 2  ? 
D N N 2  ? 
E N N 3  ? 
F N N 4  ? 
G N N 3  ? 
H N N 5  ? 
I N N 6  ? 
J N N 7  ? 
K N N 8  ? 
L N N 6  ? 
M N N 7  ? 
N N N 8  ? 
O N N 9  ? 
P N N 10 ? 
Q N N 10 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    B3GT5_HUMAN 
_struct_ref.pdbx_db_accession          Q9Y2C3 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;FKEQSFVYKKDGNFLKLPDTDCRQTPPFLVLLVTSSHKQLAERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAETKEVD
QESQRHGDIIQKDFLDVYYNLTLKTMMGIEWVHRFCPQAAFVMKTDSDMFINVDYLTELLLKKNRTTRFFTGFLKLNEFP
IRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVASQVYNVSKSVPYIKLEDVFVGLCLERLNIRLEELHSQPTFFPGG
LRFSVCLFRRIVACHFIKPRTLLDYWQALENSRGEDCP
;
_struct_ref.pdbx_align_begin           31 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZWP A 1 ? 278 ? Q9Y2C3 31 ? 308 ? 31 308 
2 1 8ZWP B 1 ? 278 ? Q9Y2C3 31 ? 308 ? 31 308 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,E,F,I,J,K,P   
2 1 B,D,G,H,L,M,N,O,Q 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN A 39  ? THR A 49  ? GLN A 69  THR A 79  1 ? 11 
HELX_P HELX_P2  AA2 SER A 72  ? GLY A 87  ? SER A 102 GLY A 117 1 ? 16 
HELX_P HELX_P3  AA3 VAL A 97  ? TYR A 99  ? VAL A 127 TYR A 129 5 ? 3  
HELX_P HELX_P4  AA4 ASN A 100 ? CYS A 116 ? ASN A 130 CYS A 146 1 ? 17 
HELX_P HELX_P5  AA5 ASN A 132 ? ASN A 144 ? ASN A 162 ASN A 174 1 ? 13 
HELX_P HELX_P6  AA6 GLY A 193 ? LYS A 204 ? GLY A 223 LYS A 234 1 ? 12 
HELX_P HELX_P7  AA7 LEU A 211 ? ASN A 224 ? LEU A 241 ASN A 254 1 ? 14 
HELX_P HELX_P8  AA8 SER A 244 ? ARG A 249 ? SER A 274 ARG A 279 1 ? 6  
HELX_P HELX_P9  AA9 LYS A 258 ? SER A 272 ? LYS A 288 SER A 302 1 ? 15 
HELX_P HELX_P10 AB1 GLN B 39  ? THR B 49  ? GLN B 69  THR B 79  1 ? 11 
HELX_P HELX_P11 AB2 SER B 72  ? GLY B 87  ? SER B 102 GLY B 117 1 ? 16 
HELX_P HELX_P12 AB3 VAL B 97  ? TYR B 99  ? VAL B 127 TYR B 129 5 ? 3  
HELX_P HELX_P13 AB4 ASN B 100 ? CYS B 116 ? ASN B 130 CYS B 146 1 ? 17 
HELX_P HELX_P14 AB5 ASN B 132 ? ASN B 144 ? ASN B 162 ASN B 174 1 ? 13 
HELX_P HELX_P15 AB6 GLY B 193 ? LYS B 204 ? GLY B 223 LYS B 234 1 ? 12 
HELX_P HELX_P16 AB7 LEU B 211 ? ASN B 224 ? LEU B 241 ASN B 254 1 ? 14 
HELX_P HELX_P17 AB8 SER B 244 ? ARG B 249 ? SER B 274 ARG B 279 1 ? 6  
HELX_P HELX_P18 AB9 LYS B 258 ? SER B 272 ? LYS B 288 SER B 302 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 22  SG  ? ? ? 1_555 A CYS 116 SG  ? ? A CYS 52  A CYS 146 1_555 ? ? ? ? ? ? ? 2.086 ? ?               
disulf2  disulf ?    ? A CYS 246 SG  ? ? ? 1_555 A CYS 277 SG  ? ? A CYS 276 A CYS 307 1_555 ? ? ? ? ? ? ? 2.037 ? ?               
disulf3  disulf ?    ? B CYS 22  SG  ? ? ? 1_555 B CYS 116 SG  ? ? B CYS 52  B CYS 146 1_555 ? ? ? ? ? ? ? 2.046 ? ?               
disulf4  disulf ?    ? B CYS 246 SG  ? ? ? 1_555 B CYS 277 SG  ? ? B CYS 276 B CYS 307 1_555 ? ? ? ? ? ? ? 2.046 ? ?               
covale1  covale one  ? A ASN 100 ND2 ? ? ? 1_555 E NAG .   C1  ? ? A ASN 130 E NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale2  covale one  ? A ASN 144 ND2 ? ? ? 1_555 F NAG .   C1  ? ? A ASN 174 F NAG 1   1_555 ? ? ? ? ? ? ? 1.445 ? N-Glycosylation 
covale3  covale one  ? B ASN 100 ND2 ? ? ? 1_555 G NAG .   C1  ? ? B ASN 130 G NAG 1   1_555 ? ? ? ? ? ? ? 1.434 ? N-Glycosylation 
covale4  covale one  ? B ASN 144 ND2 ? ? ? 1_555 H NAG .   C1  ? ? B ASN 174 H NAG 1   1_555 ? ? ? ? ? ? ? 1.417 ? N-Glycosylation 
covale5  covale one  ? B ASN 201 ND2 ? ? ? 1_555 O NAG .   C1  ? ? B ASN 231 B NAG 404 1_555 ? ? ? ? ? ? ? 1.450 ? N-Glycosylation 
covale6  covale both ? C BGC .   O4  ? ? ? 1_555 C GAL .   C1  ? ? C BGC 1   C GAL 2   1_555 ? ? ? ? ? ? ? 1.450 ? ?               
covale7  covale both ? C GAL .   O4  ? ? ? 1_555 C GLA .   C1  ? ? C GAL 2   C GLA 3   1_555 ? ? ? ? ? ? ? 1.430 ? ?               
covale8  covale both ? C GLA .   O3  ? ? ? 1_555 C NGA .   C1  ? ? C GLA 3   C NGA 4   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale9  covale both ? D BGC .   O4  ? ? ? 1_555 D GAL .   C1  ? ? D BGC 1   D GAL 2   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
covale10 covale both ? D GAL .   O4  ? ? ? 1_555 D GLA .   C1  ? ? D GAL 2   D GLA 3   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale11 covale both ? D GLA .   O3  ? ? ? 1_555 D NGA .   C1  ? ? D GLA 3   D NGA 4   1_555 ? ? ? ? ? ? ? 1.436 ? ?               
covale12 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1  ? ? E NAG 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.456 ? ?               
covale13 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1  ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
covale14 covale both ? F NAG .   O6  ? ? ? 1_555 F FUC .   C1  ? ? F NAG 1   F FUC 3   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale15 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1  ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.437 ? ?               
covale16 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1  ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.448 ? ?               
covale17 covale both ? H NAG .   O6  ? ? ? 1_555 H FUC .   C1  ? ? H NAG 1   H FUC 6   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
covale18 covale both ? H NAG .   O4  ? ? ? 1_555 H BMA .   C1  ? ? H NAG 2   H BMA 3   1_555 ? ? ? ? ? ? ? 1.428 ? ?               
covale19 covale both ? H BMA .   O3  ? ? ? 1_555 H MAN .   C1  ? ? H BMA 3   H MAN 4   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale20 covale both ? H BMA .   O6  ? ? ? 1_555 H MAN .   C1  ? ? H BMA 3   H MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
metalc1  metalc ?    ? A ASP 126 OD2 ? ? ? 1_555 I MN  .   MN  ? ? A ASP 156 A MN  401 1_555 ? ? ? ? ? ? ? 2.330 ? ?               
metalc2  metalc ?    ? A ASP 128 OD1 ? ? ? 1_555 I MN  .   MN  ? ? A ASP 158 A MN  401 1_555 ? ? ? ? ? ? ? 2.316 ? ?               
metalc3  metalc ?    ? A ASP 128 OD2 ? ? ? 1_555 I MN  .   MN  ? ? A ASP 158 A MN  401 1_555 ? ? ? ? ? ? ? 2.526 ? ?               
metalc4  metalc ?    ? A HIS 255 NE2 ? ? ? 1_555 I MN  .   MN  ? ? A HIS 285 A MN  401 1_555 ? ? ? ? ? ? ? 2.258 ? ?               
metalc5  metalc ?    ? I MN  .   MN  ? ? ? 1_555 J UDP .   O2A ? ? A MN  401 A UDP 402 1_555 ? ? ? ? ? ? ? 2.243 ? ?               
metalc6  metalc ?    ? I MN  .   MN  ? ? ? 1_555 J UDP .   O3B ? ? A MN  401 A UDP 402 1_555 ? ? ? ? ? ? ? 2.056 ? ?               
metalc7  metalc ?    ? B ASP 126 OD2 ? ? ? 1_555 L MN  .   MN  ? ? B ASP 156 B MN  401 1_555 ? ? ? ? ? ? ? 2.460 ? ?               
metalc8  metalc ?    ? B ASP 128 OD1 ? ? ? 1_555 L MN  .   MN  ? ? B ASP 158 B MN  401 1_555 ? ? ? ? ? ? ? 2.367 ? ?               
metalc9  metalc ?    ? B ASP 128 OD2 ? ? ? 1_555 L MN  .   MN  ? ? B ASP 158 B MN  401 1_555 ? ? ? ? ? ? ? 2.621 ? ?               
metalc10 metalc ?    ? B HIS 255 NE2 ? ? ? 1_555 L MN  .   MN  ? ? B HIS 285 B MN  401 1_555 ? ? ? ? ? ? ? 2.258 ? ?               
metalc11 metalc ?    ? L MN  .   MN  ? ? ? 1_555 M UDP .   O3B ? ? B MN  401 B UDP 402 1_555 ? ? ? ? ? ? ? 2.382 ? ?               
metalc12 metalc ?    ? L MN  .   MN  ? ? ? 1_555 M UDP .   O2A ? ? B MN  401 B UDP 402 1_555 ? ? ? ? ? ? ? 2.743 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD2 ? A ASP 126 ? A ASP 156 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 OD1 ? A ASP 128 ? A ASP 158 ? 1_555 89.6  ? 
2  OD2 ? A ASP 126 ? A ASP 156 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 OD2 ? A ASP 128 ? A ASP 158 ? 1_555 142.3 ? 
3  OD1 ? A ASP 128 ? A ASP 158 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 OD2 ? A ASP 128 ? A ASP 158 ? 1_555 53.1  ? 
4  OD2 ? A ASP 126 ? A ASP 156 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 NE2 ? A HIS 255 ? A HIS 285 ? 1_555 98.2  ? 
5  OD1 ? A ASP 128 ? A ASP 158 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 NE2 ? A HIS 255 ? A HIS 285 ? 1_555 96.0  ? 
6  OD2 ? A ASP 128 ? A ASP 158 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 NE2 ? A HIS 255 ? A HIS 285 ? 1_555 82.6  ? 
7  OD2 ? A ASP 126 ? A ASP 156 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O2A ? J UDP .   ? A UDP 402 ? 1_555 98.0  ? 
8  OD1 ? A ASP 128 ? A ASP 158 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O2A ? J UDP .   ? A UDP 402 ? 1_555 96.2  ? 
9  OD2 ? A ASP 128 ? A ASP 158 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O2A ? J UDP .   ? A UDP 402 ? 1_555 91.9  ? 
10 NE2 ? A HIS 255 ? A HIS 285 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O2A ? J UDP .   ? A UDP 402 ? 1_555 159.7 ? 
11 OD2 ? A ASP 126 ? A ASP 156 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O3B ? J UDP .   ? A UDP 402 ? 1_555 101.8 ? 
12 OD1 ? A ASP 128 ? A ASP 158 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O3B ? J UDP .   ? A UDP 402 ? 1_555 168.6 ? 
13 OD2 ? A ASP 128 ? A ASP 158 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O3B ? J UDP .   ? A UDP 402 ? 1_555 115.6 ? 
14 NE2 ? A HIS 255 ? A HIS 285 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O3B ? J UDP .   ? A UDP 402 ? 1_555 83.0  ? 
15 O2A ? J UDP .   ? A UDP 402 ? 1_555 MN ? I MN . ? A MN 401 ? 1_555 O3B ? J UDP .   ? A UDP 402 ? 1_555 81.8  ? 
16 OD2 ? B ASP 126 ? B ASP 156 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 OD1 ? B ASP 128 ? B ASP 158 ? 1_555 97.0  ? 
17 OD2 ? B ASP 126 ? B ASP 156 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 OD2 ? B ASP 128 ? B ASP 158 ? 1_555 146.3 ? 
18 OD1 ? B ASP 128 ? B ASP 158 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 OD2 ? B ASP 128 ? B ASP 158 ? 1_555 52.2  ? 
19 OD2 ? B ASP 126 ? B ASP 156 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 NE2 ? B HIS 255 ? B HIS 285 ? 1_555 97.4  ? 
20 OD1 ? B ASP 128 ? B ASP 158 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 NE2 ? B HIS 255 ? B HIS 285 ? 1_555 94.5  ? 
21 OD2 ? B ASP 128 ? B ASP 158 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 NE2 ? B HIS 255 ? B HIS 285 ? 1_555 75.1  ? 
22 OD2 ? B ASP 126 ? B ASP 156 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O3B ? M UDP .   ? B UDP 402 ? 1_555 85.3  ? 
23 OD1 ? B ASP 128 ? B ASP 158 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O3B ? M UDP .   ? B UDP 402 ? 1_555 176.1 ? 
24 OD2 ? B ASP 128 ? B ASP 158 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O3B ? M UDP .   ? B UDP 402 ? 1_555 126.4 ? 
25 NE2 ? B HIS 255 ? B HIS 285 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O3B ? M UDP .   ? B UDP 402 ? 1_555 88.3  ? 
26 OD2 ? B ASP 126 ? B ASP 156 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O2A ? M UDP .   ? B UDP 402 ? 1_555 109.9 ? 
27 OD1 ? B ASP 128 ? B ASP 158 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O2A ? M UDP .   ? B UDP 402 ? 1_555 95.3  ? 
28 OD2 ? B ASP 128 ? B ASP 158 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O2A ? M UDP .   ? B UDP 402 ? 1_555 88.5  ? 
29 NE2 ? B HIS 255 ? B HIS 285 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O2A ? M UDP .   ? B UDP 402 ? 1_555 149.5 ? 
30 O3B ? M UDP .   ? B UDP 402 ? 1_555 MN ? L MN . ? B MN 401 ? 1_555 O2A ? M UDP .   ? B UDP 402 ? 1_555 80.9  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG E .   ? ASN A 100 ? NAG E 1   ? 1_555 ASN A 130 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG F .   ? ASN A 144 ? NAG F 1   ? 1_555 ASN A 174 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG G .   ? ASN B 100 ? NAG G 1   ? 1_555 ASN B 130 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG H .   ? ASN B 144 ? NAG H 1   ? 1_555 ASN B 174 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 NAG O .   ? ASN B 201 ? NAG B 404 ? 1_555 ASN B 231 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6 CYS A 22  ? CYS A 116 ? CYS A 52  ? 1_555 CYS A 146 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7 CYS A 246 ? CYS A 277 ? CYS A 276 ? 1_555 CYS A 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8 CYS B 22  ? CYS B 116 ? CYS B 52  ? 1_555 CYS B 146 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9 CYS B 246 ? CYS B 277 ? CYS B 276 ? 1_555 CYS B 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 7 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 3 ? 
AA6 ? 6 ? 
AA7 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? anti-parallel 
AA2 6 7 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
AA6 4 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 14  ? LYS A 16  ? PHE A 44  LYS A 46  
AA1 2 ILE A 89  ? LEU A 95  ? ILE A 119 LEU A 125 
AA1 3 LYS A 59  ? THR A 69  ? LYS A 89  THR A 99  
AA1 4 ARG A 54  ? VAL A 56  ? ARG A 84  VAL A 86  
AA2 1 PHE A 14  ? LYS A 16  ? PHE A 44  LYS A 46  
AA2 2 ILE A 89  ? LEU A 95  ? ILE A 119 LEU A 125 
AA2 3 LYS A 59  ? THR A 69  ? LYS A 89  THR A 99  
AA2 4 LEU A 29  ? THR A 34  ? LEU A 59  THR A 64  
AA2 5 PHE A 121 ? THR A 125 ? PHE A 151 THR A 155 
AA2 6 GLY A 188 ? SER A 192 ? GLY A 218 SER A 222 
AA2 7 PHE A 150 ? THR A 151 ? PHE A 180 THR A 181 
AA3 1 MET A 129 ? ILE A 131 ? MET A 159 ILE A 161 
AA3 2 ALA A 253 ? HIS A 255 ? ALA A 283 HIS A 285 
AA3 3 PHE A 236 ? PHE A 237 ? PHE A 266 PHE A 267 
AA4 1 LEU A 154 ? LYS A 155 ? LEU A 184 LYS A 185 
AA4 2 PHE A 183 ? CYS A 184 ? PHE A 213 CYS A 214 
AA5 1 ARG B 54  ? VAL B 56  ? ARG B 84  VAL B 86  
AA5 2 LYS B 59  ? THR B 69  ? LYS B 89  THR B 99  
AA5 3 ILE B 89  ? LEU B 95  ? ILE B 119 LEU B 125 
AA6 1 ARG B 54  ? VAL B 56  ? ARG B 84  VAL B 86  
AA6 2 LYS B 59  ? THR B 69  ? LYS B 89  THR B 99  
AA6 3 LEU B 29  ? THR B 34  ? LEU B 59  THR B 64  
AA6 4 PHE B 121 ? THR B 125 ? PHE B 151 THR B 155 
AA6 5 PHE B 183 ? SER B 192 ? PHE B 213 SER B 222 
AA6 6 PHE B 150 ? LYS B 155 ? PHE B 180 LYS B 185 
AA7 1 MET B 129 ? ILE B 131 ? MET B 159 ILE B 161 
AA7 2 ALA B 253 ? HIS B 255 ? ALA B 283 HIS B 285 
AA7 3 PHE B 236 ? PHE B 237 ? PHE B 266 PHE B 267 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 15  ? N LEU A 45  O GLN A 91  ? O GLN A 121 
AA1 2 3 O PHE A 94  ? O PHE A 124 N THR A 69  ? N THR A 99  
AA1 3 4 O LYS A 59  ? O LYS A 89  N VAL A 56  ? N VAL A 86  
AA2 1 2 N LEU A 15  ? N LEU A 45  O GLN A 91  ? O GLN A 121 
AA2 2 3 O PHE A 94  ? O PHE A 124 N THR A 69  ? N THR A 99  
AA2 3 4 O LYS A 62  ? O LYS A 92  N LEU A 31  ? N LEU A 61  
AA2 4 5 N LEU A 32  ? N LEU A 62  O MET A 123 ? O MET A 153 
AA2 5 6 N VAL A 122 ? N VAL A 152 O PHE A 191 ? O PHE A 221 
AA2 6 7 O VAL A 190 ? O VAL A 220 N THR A 151 ? N THR A 181 
AA3 1 2 N PHE A 130 ? N PHE A 160 O CYS A 254 ? O CYS A 284 
AA3 2 3 O HIS A 255 ? O HIS A 285 N PHE A 237 ? N PHE A 267 
AA4 1 2 N LYS A 155 ? N LYS A 185 O PHE A 183 ? O PHE A 213 
AA5 1 2 N VAL B 56  ? N VAL B 86  O LYS B 59  ? O LYS B 89  
AA5 2 3 N THR B 69  ? N THR B 99  O PHE B 94  ? O PHE B 124 
AA6 1 2 N VAL B 56  ? N VAL B 86  O LYS B 59  ? O LYS B 89  
AA6 2 3 O LYS B 62  ? O LYS B 92  N LEU B 31  ? N LEU B 61  
AA6 3 4 N VAL B 30  ? N VAL B 60  O MET B 123 ? O MET B 153 
AA6 4 5 N VAL B 122 ? N VAL B 152 O PHE B 191 ? O PHE B 221 
AA6 5 6 O PHE B 183 ? O PHE B 213 N LYS B 155 ? N LYS B 185 
AA7 1 2 N PHE B 130 ? N PHE B 160 O CYS B 254 ? O CYS B 284 
AA7 2 3 O HIS B 255 ? O HIS B 285 N PHE B 237 ? N PHE B 267 
# 
_pdbx_entry_details.entry_id                   8ZWP 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O A HOH 535 ? ? O A HOH 564 ? ? 2.08 
2 1 O A HOH 511 ? ? O A HOH 653 ? ? 2.10 
3 1 O A HOH 627 ? ? O A HOH 685 ? ? 2.17 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    NH1 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    ARG 
_pdbx_validate_symm_contact.auth_seq_id_1     209 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O3 
_pdbx_validate_symm_contact.auth_asym_id_2    H 
_pdbx_validate_symm_contact.auth_comp_id_2    NAG 
_pdbx_validate_symm_contact.auth_seq_id_2     1 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   1_656 
_pdbx_validate_symm_contact.dist              2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN A 43  ? ? 84.27   32.02   
2 1 GLN A 69  ? ? -81.15  44.96   
3 1 THR A 79  ? ? -125.22 -110.22 
4 1 CYS A 146 ? ? -144.76 51.05   
5 1 ASP A 158 ? ? -90.79  58.42   
6 1 CYS A 307 ? ? -137.40 -67.55  
7 1 GLN B 69  ? ? -81.68  45.79   
8 1 THR B 79  ? ? -125.54 -113.20 
9 1 CYS B 146 ? ? -146.56 48.94   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A PHE 31 ? A PHE 1  
2  1 Y 1 A LYS 32 ? A LYS 2  
3  1 Y 1 A GLU 33 ? A GLU 3  
4  1 Y 1 A GLN 34 ? A GLN 4  
5  1 Y 1 A SER 35 ? A SER 5  
6  1 Y 1 A PHE 36 ? A PHE 6  
7  1 Y 1 A VAL 37 ? A VAL 7  
8  1 Y 1 A TYR 38 ? A TYR 8  
9  1 Y 1 A LYS 39 ? A LYS 9  
10 1 Y 1 A LYS 40 ? A LYS 10 
11 1 Y 1 A ASP 41 ? A ASP 11 
12 1 Y 1 B PHE 31 ? B PHE 1  
13 1 Y 1 B LYS 32 ? B LYS 2  
14 1 Y 1 B GLU 33 ? B GLU 3  
15 1 Y 1 B GLN 34 ? B GLN 4  
16 1 Y 1 B SER 35 ? B SER 5  
17 1 Y 1 B PHE 36 ? B PHE 6  
18 1 Y 1 B VAL 37 ? B VAL 7  
19 1 Y 1 B TYR 38 ? B TYR 8  
20 1 Y 1 B LYS 39 ? B LYS 9  
21 1 Y 1 B LYS 40 ? B LYS 10 
22 1 Y 1 B ASP 41 ? B ASP 11 
23 1 Y 1 B GLY 42 ? B GLY 12 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
B3P C1     C  N N 74  
B3P C2     C  N N 75  
B3P C3     C  N N 76  
B3P N1     N  N N 77  
B3P C4     C  N N 78  
B3P C5     C  N N 79  
B3P C6     C  N N 80  
B3P C7     C  N N 81  
B3P N2     N  N N 82  
B3P C8     C  N N 83  
B3P C9     C  N N 84  
B3P C10    C  N N 85  
B3P C11    C  N N 86  
B3P O1     O  N N 87  
B3P O2     O  N N 88  
B3P O3     O  N N 89  
B3P O4     O  N N 90  
B3P O5     O  N N 91  
B3P O6     O  N N 92  
B3P H11    H  N N 93  
B3P H12    H  N N 94  
B3P H21    H  N N 95  
B3P H22    H  N N 96  
B3P H31    H  N N 97  
B3P H32    H  N N 98  
B3P HN1    H  N N 99  
B3P H51    H  N N 100 
B3P H52    H  N N 101 
B3P H61    H  N N 102 
B3P H62    H  N N 103 
B3P H71    H  N N 104 
B3P H72    H  N N 105 
B3P HN2    H  N N 106 
B3P H91    H  N N 107 
B3P H92    H  N N 108 
B3P H101   H  N N 109 
B3P H102   H  N N 110 
B3P H111   H  N N 111 
B3P H112   H  N N 112 
B3P HO1    H  N N 113 
B3P HO2    H  N N 114 
B3P HO3    H  N N 115 
B3P HO4    H  N N 116 
B3P HO5    H  N N 117 
B3P HO6    H  N N 118 
BGC C2     C  N R 119 
BGC C3     C  N S 120 
BGC C4     C  N S 121 
BGC C5     C  N R 122 
BGC C6     C  N N 123 
BGC C1     C  N R 124 
BGC O1     O  N N 125 
BGC O2     O  N N 126 
BGC O3     O  N N 127 
BGC O4     O  N N 128 
BGC O5     O  N N 129 
BGC O6     O  N N 130 
BGC H2     H  N N 131 
BGC H3     H  N N 132 
BGC H4     H  N N 133 
BGC H5     H  N N 134 
BGC H61    H  N N 135 
BGC H62    H  N N 136 
BGC H1     H  N N 137 
BGC HO1    H  N N 138 
BGC HO2    H  N N 139 
BGC HO3    H  N N 140 
BGC HO4    H  N N 141 
BGC HO6    H  N N 142 
BMA C1     C  N R 143 
BMA C2     C  N S 144 
BMA C3     C  N S 145 
BMA C4     C  N S 146 
BMA C5     C  N R 147 
BMA C6     C  N N 148 
BMA O1     O  N N 149 
BMA O2     O  N N 150 
BMA O3     O  N N 151 
BMA O4     O  N N 152 
BMA O5     O  N N 153 
BMA O6     O  N N 154 
BMA H1     H  N N 155 
BMA H2     H  N N 156 
BMA H3     H  N N 157 
BMA H4     H  N N 158 
BMA H5     H  N N 159 
BMA H61    H  N N 160 
BMA H62    H  N N 161 
BMA HO1    H  N N 162 
BMA HO2    H  N N 163 
BMA HO3    H  N N 164 
BMA HO4    H  N N 165 
BMA HO6    H  N N 166 
CYS N      N  N N 167 
CYS CA     C  N R 168 
CYS C      C  N N 169 
CYS O      O  N N 170 
CYS CB     C  N N 171 
CYS SG     S  N N 172 
CYS OXT    O  N N 173 
CYS H      H  N N 174 
CYS H2     H  N N 175 
CYS HA     H  N N 176 
CYS HB2    H  N N 177 
CYS HB3    H  N N 178 
CYS HG     H  N N 179 
CYS HXT    H  N N 180 
FUC C1     C  N R 181 
FUC C2     C  N S 182 
FUC C3     C  N R 183 
FUC C4     C  N S 184 
FUC C5     C  N S 185 
FUC C6     C  N N 186 
FUC O1     O  N N 187 
FUC O2     O  N N 188 
FUC O3     O  N N 189 
FUC O4     O  N N 190 
FUC O5     O  N N 191 
FUC H1     H  N N 192 
FUC H2     H  N N 193 
FUC H3     H  N N 194 
FUC H4     H  N N 195 
FUC H5     H  N N 196 
FUC H61    H  N N 197 
FUC H62    H  N N 198 
FUC H63    H  N N 199 
FUC HO1    H  N N 200 
FUC HO2    H  N N 201 
FUC HO3    H  N N 202 
FUC HO4    H  N N 203 
GAL C1     C  N R 204 
GAL C2     C  N R 205 
GAL C3     C  N S 206 
GAL C4     C  N R 207 
GAL C5     C  N R 208 
GAL C6     C  N N 209 
GAL O1     O  N N 210 
GAL O2     O  N N 211 
GAL O3     O  N N 212 
GAL O4     O  N N 213 
GAL O5     O  N N 214 
GAL O6     O  N N 215 
GAL H1     H  N N 216 
GAL H2     H  N N 217 
GAL H3     H  N N 218 
GAL H4     H  N N 219 
GAL H5     H  N N 220 
GAL H61    H  N N 221 
GAL H62    H  N N 222 
GAL HO1    H  N N 223 
GAL HO2    H  N N 224 
GAL HO3    H  N N 225 
GAL HO4    H  N N 226 
GAL HO6    H  N N 227 
GLA C1     C  N S 228 
GLA C2     C  N R 229 
GLA C3     C  N S 230 
GLA C4     C  N R 231 
GLA C5     C  N R 232 
GLA C6     C  N N 233 
GLA O1     O  N N 234 
GLA O2     O  N N 235 
GLA O3     O  N N 236 
GLA O4     O  N N 237 
GLA O5     O  N N 238 
GLA O6     O  N N 239 
GLA H1     H  N N 240 
GLA H2     H  N N 241 
GLA H3     H  N N 242 
GLA H4     H  N N 243 
GLA H5     H  N N 244 
GLA H61    H  N N 245 
GLA H62    H  N N 246 
GLA HO1    H  N N 247 
GLA HO2    H  N N 248 
GLA HO3    H  N N 249 
GLA HO4    H  N N 250 
GLA HO6    H  N N 251 
GLN N      N  N N 252 
GLN CA     C  N S 253 
GLN C      C  N N 254 
GLN O      O  N N 255 
GLN CB     C  N N 256 
GLN CG     C  N N 257 
GLN CD     C  N N 258 
GLN OE1    O  N N 259 
GLN NE2    N  N N 260 
GLN OXT    O  N N 261 
GLN H      H  N N 262 
GLN H2     H  N N 263 
GLN HA     H  N N 264 
GLN HB2    H  N N 265 
GLN HB3    H  N N 266 
GLN HG2    H  N N 267 
GLN HG3    H  N N 268 
GLN HE21   H  N N 269 
GLN HE22   H  N N 270 
GLN HXT    H  N N 271 
GLU N      N  N N 272 
GLU CA     C  N S 273 
GLU C      C  N N 274 
GLU O      O  N N 275 
GLU CB     C  N N 276 
GLU CG     C  N N 277 
GLU CD     C  N N 278 
GLU OE1    O  N N 279 
GLU OE2    O  N N 280 
GLU OXT    O  N N 281 
GLU H      H  N N 282 
GLU H2     H  N N 283 
GLU HA     H  N N 284 
GLU HB2    H  N N 285 
GLU HB3    H  N N 286 
GLU HG2    H  N N 287 
GLU HG3    H  N N 288 
GLU HE2    H  N N 289 
GLU HXT    H  N N 290 
GLY N      N  N N 291 
GLY CA     C  N N 292 
GLY C      C  N N 293 
GLY O      O  N N 294 
GLY OXT    O  N N 295 
GLY H      H  N N 296 
GLY H2     H  N N 297 
GLY HA2    H  N N 298 
GLY HA3    H  N N 299 
GLY HXT    H  N N 300 
HIS N      N  N N 301 
HIS CA     C  N S 302 
HIS C      C  N N 303 
HIS O      O  N N 304 
HIS CB     C  N N 305 
HIS CG     C  Y N 306 
HIS ND1    N  Y N 307 
HIS CD2    C  Y N 308 
HIS CE1    C  Y N 309 
HIS NE2    N  Y N 310 
HIS OXT    O  N N 311 
HIS H      H  N N 312 
HIS H2     H  N N 313 
HIS HA     H  N N 314 
HIS HB2    H  N N 315 
HIS HB3    H  N N 316 
HIS HD1    H  N N 317 
HIS HD2    H  N N 318 
HIS HE1    H  N N 319 
HIS HE2    H  N N 320 
HIS HXT    H  N N 321 
HOH O      O  N N 322 
HOH H1     H  N N 323 
HOH H2     H  N N 324 
ILE N      N  N N 325 
ILE CA     C  N S 326 
ILE C      C  N N 327 
ILE O      O  N N 328 
ILE CB     C  N S 329 
ILE CG1    C  N N 330 
ILE CG2    C  N N 331 
ILE CD1    C  N N 332 
ILE OXT    O  N N 333 
ILE H      H  N N 334 
ILE H2     H  N N 335 
ILE HA     H  N N 336 
ILE HB     H  N N 337 
ILE HG12   H  N N 338 
ILE HG13   H  N N 339 
ILE HG21   H  N N 340 
ILE HG22   H  N N 341 
ILE HG23   H  N N 342 
ILE HD11   H  N N 343 
ILE HD12   H  N N 344 
ILE HD13   H  N N 345 
ILE HXT    H  N N 346 
LEU N      N  N N 347 
LEU CA     C  N S 348 
LEU C      C  N N 349 
LEU O      O  N N 350 
LEU CB     C  N N 351 
LEU CG     C  N N 352 
LEU CD1    C  N N 353 
LEU CD2    C  N N 354 
LEU OXT    O  N N 355 
LEU H      H  N N 356 
LEU H2     H  N N 357 
LEU HA     H  N N 358 
LEU HB2    H  N N 359 
LEU HB3    H  N N 360 
LEU HG     H  N N 361 
LEU HD11   H  N N 362 
LEU HD12   H  N N 363 
LEU HD13   H  N N 364 
LEU HD21   H  N N 365 
LEU HD22   H  N N 366 
LEU HD23   H  N N 367 
LEU HXT    H  N N 368 
LYS N      N  N N 369 
LYS CA     C  N S 370 
LYS C      C  N N 371 
LYS O      O  N N 372 
LYS CB     C  N N 373 
LYS CG     C  N N 374 
LYS CD     C  N N 375 
LYS CE     C  N N 376 
LYS NZ     N  N N 377 
LYS OXT    O  N N 378 
LYS H      H  N N 379 
LYS H2     H  N N 380 
LYS HA     H  N N 381 
LYS HB2    H  N N 382 
LYS HB3    H  N N 383 
LYS HG2    H  N N 384 
LYS HG3    H  N N 385 
LYS HD2    H  N N 386 
LYS HD3    H  N N 387 
LYS HE2    H  N N 388 
LYS HE3    H  N N 389 
LYS HZ1    H  N N 390 
LYS HZ2    H  N N 391 
LYS HZ3    H  N N 392 
LYS HXT    H  N N 393 
MAN C1     C  N S 394 
MAN C2     C  N S 395 
MAN C3     C  N S 396 
MAN C4     C  N S 397 
MAN C5     C  N R 398 
MAN C6     C  N N 399 
MAN O1     O  N N 400 
MAN O2     O  N N 401 
MAN O3     O  N N 402 
MAN O4     O  N N 403 
MAN O5     O  N N 404 
MAN O6     O  N N 405 
MAN H1     H  N N 406 
MAN H2     H  N N 407 
MAN H3     H  N N 408 
MAN H4     H  N N 409 
MAN H5     H  N N 410 
MAN H61    H  N N 411 
MAN H62    H  N N 412 
MAN HO1    H  N N 413 
MAN HO2    H  N N 414 
MAN HO3    H  N N 415 
MAN HO4    H  N N 416 
MAN HO6    H  N N 417 
MET N      N  N N 418 
MET CA     C  N S 419 
MET C      C  N N 420 
MET O      O  N N 421 
MET CB     C  N N 422 
MET CG     C  N N 423 
MET SD     S  N N 424 
MET CE     C  N N 425 
MET OXT    O  N N 426 
MET H      H  N N 427 
MET H2     H  N N 428 
MET HA     H  N N 429 
MET HB2    H  N N 430 
MET HB3    H  N N 431 
MET HG2    H  N N 432 
MET HG3    H  N N 433 
MET HE1    H  N N 434 
MET HE2    H  N N 435 
MET HE3    H  N N 436 
MET HXT    H  N N 437 
MN  MN     MN N N 438 
NAG C1     C  N R 439 
NAG C2     C  N R 440 
NAG C3     C  N R 441 
NAG C4     C  N S 442 
NAG C5     C  N R 443 
NAG C6     C  N N 444 
NAG C7     C  N N 445 
NAG C8     C  N N 446 
NAG N2     N  N N 447 
NAG O1     O  N N 448 
NAG O3     O  N N 449 
NAG O4     O  N N 450 
NAG O5     O  N N 451 
NAG O6     O  N N 452 
NAG O7     O  N N 453 
NAG H1     H  N N 454 
NAG H2     H  N N 455 
NAG H3     H  N N 456 
NAG H4     H  N N 457 
NAG H5     H  N N 458 
NAG H61    H  N N 459 
NAG H62    H  N N 460 
NAG H81    H  N N 461 
NAG H82    H  N N 462 
NAG H83    H  N N 463 
NAG HN2    H  N N 464 
NAG HO1    H  N N 465 
NAG HO3    H  N N 466 
NAG HO4    H  N N 467 
NAG HO6    H  N N 468 
NGA C1     C  N R 469 
NGA C2     C  N R 470 
NGA C3     C  N R 471 
NGA C4     C  N R 472 
NGA C5     C  N R 473 
NGA C6     C  N N 474 
NGA C7     C  N N 475 
NGA C8     C  N N 476 
NGA N2     N  N N 477 
NGA O1     O  N N 478 
NGA O3     O  N N 479 
NGA O4     O  N N 480 
NGA O5     O  N N 481 
NGA O6     O  N N 482 
NGA O7     O  N N 483 
NGA H1     H  N N 484 
NGA H2     H  N N 485 
NGA H3     H  N N 486 
NGA H4     H  N N 487 
NGA H5     H  N N 488 
NGA H61    H  N N 489 
NGA H62    H  N N 490 
NGA H81    H  N N 491 
NGA H82    H  N N 492 
NGA H83    H  N N 493 
NGA HN2    H  N N 494 
NGA HO1    H  N N 495 
NGA HO3    H  N N 496 
NGA HO4    H  N N 497 
NGA HO6    H  N N 498 
PHE N      N  N N 499 
PHE CA     C  N S 500 
PHE C      C  N N 501 
PHE O      O  N N 502 
PHE CB     C  N N 503 
PHE CG     C  Y N 504 
PHE CD1    C  Y N 505 
PHE CD2    C  Y N 506 
PHE CE1    C  Y N 507 
PHE CE2    C  Y N 508 
PHE CZ     C  Y N 509 
PHE OXT    O  N N 510 
PHE H      H  N N 511 
PHE H2     H  N N 512 
PHE HA     H  N N 513 
PHE HB2    H  N N 514 
PHE HB3    H  N N 515 
PHE HD1    H  N N 516 
PHE HD2    H  N N 517 
PHE HE1    H  N N 518 
PHE HE2    H  N N 519 
PHE HZ     H  N N 520 
PHE HXT    H  N N 521 
PRO N      N  N N 522 
PRO CA     C  N S 523 
PRO C      C  N N 524 
PRO O      O  N N 525 
PRO CB     C  N N 526 
PRO CG     C  N N 527 
PRO CD     C  N N 528 
PRO OXT    O  N N 529 
PRO H      H  N N 530 
PRO HA     H  N N 531 
PRO HB2    H  N N 532 
PRO HB3    H  N N 533 
PRO HG2    H  N N 534 
PRO HG3    H  N N 535 
PRO HD2    H  N N 536 
PRO HD3    H  N N 537 
PRO HXT    H  N N 538 
SER N      N  N N 539 
SER CA     C  N S 540 
SER C      C  N N 541 
SER O      O  N N 542 
SER CB     C  N N 543 
SER OG     O  N N 544 
SER OXT    O  N N 545 
SER H      H  N N 546 
SER H2     H  N N 547 
SER HA     H  N N 548 
SER HB2    H  N N 549 
SER HB3    H  N N 550 
SER HG     H  N N 551 
SER HXT    H  N N 552 
THR N      N  N N 553 
THR CA     C  N S 554 
THR C      C  N N 555 
THR O      O  N N 556 
THR CB     C  N R 557 
THR OG1    O  N N 558 
THR CG2    C  N N 559 
THR OXT    O  N N 560 
THR H      H  N N 561 
THR H2     H  N N 562 
THR HA     H  N N 563 
THR HB     H  N N 564 
THR HG1    H  N N 565 
THR HG21   H  N N 566 
THR HG22   H  N N 567 
THR HG23   H  N N 568 
THR HXT    H  N N 569 
TRP N      N  N N 570 
TRP CA     C  N S 571 
TRP C      C  N N 572 
TRP O      O  N N 573 
TRP CB     C  N N 574 
TRP CG     C  Y N 575 
TRP CD1    C  Y N 576 
TRP CD2    C  Y N 577 
TRP NE1    N  Y N 578 
TRP CE2    C  Y N 579 
TRP CE3    C  Y N 580 
TRP CZ2    C  Y N 581 
TRP CZ3    C  Y N 582 
TRP CH2    C  Y N 583 
TRP OXT    O  N N 584 
TRP H      H  N N 585 
TRP H2     H  N N 586 
TRP HA     H  N N 587 
TRP HB2    H  N N 588 
TRP HB3    H  N N 589 
TRP HD1    H  N N 590 
TRP HE1    H  N N 591 
TRP HE3    H  N N 592 
TRP HZ2    H  N N 593 
TRP HZ3    H  N N 594 
TRP HH2    H  N N 595 
TRP HXT    H  N N 596 
TYR N      N  N N 597 
TYR CA     C  N S 598 
TYR C      C  N N 599 
TYR O      O  N N 600 
TYR CB     C  N N 601 
TYR CG     C  Y N 602 
TYR CD1    C  Y N 603 
TYR CD2    C  Y N 604 
TYR CE1    C  Y N 605 
TYR CE2    C  Y N 606 
TYR CZ     C  Y N 607 
TYR OH     O  N N 608 
TYR OXT    O  N N 609 
TYR H      H  N N 610 
TYR H2     H  N N 611 
TYR HA     H  N N 612 
TYR HB2    H  N N 613 
TYR HB3    H  N N 614 
TYR HD1    H  N N 615 
TYR HD2    H  N N 616 
TYR HE1    H  N N 617 
TYR HE2    H  N N 618 
TYR HH     H  N N 619 
TYR HXT    H  N N 620 
UDP N1     N  N N 621 
UDP C2     C  N N 622 
UDP N3     N  N N 623 
UDP C4     C  N N 624 
UDP C5     C  N N 625 
UDP C6     C  N N 626 
UDP O2     O  N N 627 
UDP O4     O  N N 628 
UDP "C1'"  C  N R 629 
UDP "C2'"  C  N R 630 
UDP "O2'"  O  N N 631 
UDP "C3'"  C  N S 632 
UDP "C4'"  C  N R 633 
UDP "O4'"  O  N N 634 
UDP "O3'"  O  N N 635 
UDP "C5'"  C  N N 636 
UDP "O5'"  O  N N 637 
UDP PA     P  N N 638 
UDP O1A    O  N N 639 
UDP O2A    O  N N 640 
UDP O3A    O  N N 641 
UDP PB     P  N N 642 
UDP O1B    O  N N 643 
UDP O2B    O  N N 644 
UDP O3B    O  N N 645 
UDP HN3    H  N N 646 
UDP H5     H  N N 647 
UDP H6     H  N N 648 
UDP "H1'"  H  N N 649 
UDP "H2'"  H  N N 650 
UDP "HO2'" H  N N 651 
UDP "H3'"  H  N N 652 
UDP "H4'"  H  N N 653 
UDP "HO3'" H  N N 654 
UDP "H5'1" H  N N 655 
UDP "H5'2" H  N N 656 
UDP HOA2   H  N N 657 
UDP HOB2   H  N N 658 
UDP HOB3   H  N N 659 
VAL N      N  N N 660 
VAL CA     C  N S 661 
VAL C      C  N N 662 
VAL O      O  N N 663 
VAL CB     C  N N 664 
VAL CG1    C  N N 665 
VAL CG2    C  N N 666 
VAL OXT    O  N N 667 
VAL H      H  N N 668 
VAL H2     H  N N 669 
VAL HA     H  N N 670 
VAL HB     H  N N 671 
VAL HG11   H  N N 672 
VAL HG12   H  N N 673 
VAL HG13   H  N N 674 
VAL HG21   H  N N 675 
VAL HG22   H  N N 676 
VAL HG23   H  N N 677 
VAL HXT    H  N N 678 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
B3P C1    C2     sing N N 70  
B3P C1    C3     sing N N 71  
B3P C1    H11    sing N N 72  
B3P C1    H12    sing N N 73  
B3P C2    N2     sing N N 74  
B3P C2    H21    sing N N 75  
B3P C2    H22    sing N N 76  
B3P C3    N1     sing N N 77  
B3P C3    H31    sing N N 78  
B3P C3    H32    sing N N 79  
B3P N1    C4     sing N N 80  
B3P N1    HN1    sing N N 81  
B3P C4    C5     sing N N 82  
B3P C4    C6     sing N N 83  
B3P C4    C7     sing N N 84  
B3P C5    O4     sing N N 85  
B3P C5    H51    sing N N 86  
B3P C5    H52    sing N N 87  
B3P C6    O5     sing N N 88  
B3P C6    H61    sing N N 89  
B3P C6    H62    sing N N 90  
B3P C7    O6     sing N N 91  
B3P C7    H71    sing N N 92  
B3P C7    H72    sing N N 93  
B3P N2    C8     sing N N 94  
B3P N2    HN2    sing N N 95  
B3P C8    C9     sing N N 96  
B3P C8    C10    sing N N 97  
B3P C8    C11    sing N N 98  
B3P C9    O1     sing N N 99  
B3P C9    H91    sing N N 100 
B3P C9    H92    sing N N 101 
B3P C10   O2     sing N N 102 
B3P C10   H101   sing N N 103 
B3P C10   H102   sing N N 104 
B3P C11   O3     sing N N 105 
B3P C11   H111   sing N N 106 
B3P C11   H112   sing N N 107 
B3P O1    HO1    sing N N 108 
B3P O2    HO2    sing N N 109 
B3P O3    HO3    sing N N 110 
B3P O4    HO4    sing N N 111 
B3P O5    HO5    sing N N 112 
B3P O6    HO6    sing N N 113 
BGC C2    C3     sing N N 114 
BGC C2    C1     sing N N 115 
BGC C2    O2     sing N N 116 
BGC C2    H2     sing N N 117 
BGC C3    C4     sing N N 118 
BGC C3    O3     sing N N 119 
BGC C3    H3     sing N N 120 
BGC C4    C5     sing N N 121 
BGC C4    O4     sing N N 122 
BGC C4    H4     sing N N 123 
BGC C5    C6     sing N N 124 
BGC C5    O5     sing N N 125 
BGC C5    H5     sing N N 126 
BGC C6    O6     sing N N 127 
BGC C6    H61    sing N N 128 
BGC C6    H62    sing N N 129 
BGC C1    O1     sing N N 130 
BGC C1    O5     sing N N 131 
BGC C1    H1     sing N N 132 
BGC O1    HO1    sing N N 133 
BGC O2    HO2    sing N N 134 
BGC O3    HO3    sing N N 135 
BGC O4    HO4    sing N N 136 
BGC O6    HO6    sing N N 137 
BMA C1    C2     sing N N 138 
BMA C1    O1     sing N N 139 
BMA C1    O5     sing N N 140 
BMA C1    H1     sing N N 141 
BMA C2    C3     sing N N 142 
BMA C2    O2     sing N N 143 
BMA C2    H2     sing N N 144 
BMA C3    C4     sing N N 145 
BMA C3    O3     sing N N 146 
BMA C3    H3     sing N N 147 
BMA C4    C5     sing N N 148 
BMA C4    O4     sing N N 149 
BMA C4    H4     sing N N 150 
BMA C5    C6     sing N N 151 
BMA C5    O5     sing N N 152 
BMA C5    H5     sing N N 153 
BMA C6    O6     sing N N 154 
BMA C6    H61    sing N N 155 
BMA C6    H62    sing N N 156 
BMA O1    HO1    sing N N 157 
BMA O2    HO2    sing N N 158 
BMA O3    HO3    sing N N 159 
BMA O4    HO4    sing N N 160 
BMA O6    HO6    sing N N 161 
CYS N     CA     sing N N 162 
CYS N     H      sing N N 163 
CYS N     H2     sing N N 164 
CYS CA    C      sing N N 165 
CYS CA    CB     sing N N 166 
CYS CA    HA     sing N N 167 
CYS C     O      doub N N 168 
CYS C     OXT    sing N N 169 
CYS CB    SG     sing N N 170 
CYS CB    HB2    sing N N 171 
CYS CB    HB3    sing N N 172 
CYS SG    HG     sing N N 173 
CYS OXT   HXT    sing N N 174 
FUC C1    C2     sing N N 175 
FUC C1    O1     sing N N 176 
FUC C1    O5     sing N N 177 
FUC C1    H1     sing N N 178 
FUC C2    C3     sing N N 179 
FUC C2    O2     sing N N 180 
FUC C2    H2     sing N N 181 
FUC C3    C4     sing N N 182 
FUC C3    O3     sing N N 183 
FUC C3    H3     sing N N 184 
FUC C4    C5     sing N N 185 
FUC C4    O4     sing N N 186 
FUC C4    H4     sing N N 187 
FUC C5    C6     sing N N 188 
FUC C5    O5     sing N N 189 
FUC C5    H5     sing N N 190 
FUC C6    H61    sing N N 191 
FUC C6    H62    sing N N 192 
FUC C6    H63    sing N N 193 
FUC O1    HO1    sing N N 194 
FUC O2    HO2    sing N N 195 
FUC O3    HO3    sing N N 196 
FUC O4    HO4    sing N N 197 
GAL C1    C2     sing N N 198 
GAL C1    O1     sing N N 199 
GAL C1    O5     sing N N 200 
GAL C1    H1     sing N N 201 
GAL C2    C3     sing N N 202 
GAL C2    O2     sing N N 203 
GAL C2    H2     sing N N 204 
GAL C3    C4     sing N N 205 
GAL C3    O3     sing N N 206 
GAL C3    H3     sing N N 207 
GAL C4    C5     sing N N 208 
GAL C4    O4     sing N N 209 
GAL C4    H4     sing N N 210 
GAL C5    C6     sing N N 211 
GAL C5    O5     sing N N 212 
GAL C5    H5     sing N N 213 
GAL C6    O6     sing N N 214 
GAL C6    H61    sing N N 215 
GAL C6    H62    sing N N 216 
GAL O1    HO1    sing N N 217 
GAL O2    HO2    sing N N 218 
GAL O3    HO3    sing N N 219 
GAL O4    HO4    sing N N 220 
GAL O6    HO6    sing N N 221 
GLA C1    C2     sing N N 222 
GLA C1    O1     sing N N 223 
GLA C1    O5     sing N N 224 
GLA C1    H1     sing N N 225 
GLA C2    C3     sing N N 226 
GLA C2    O2     sing N N 227 
GLA C2    H2     sing N N 228 
GLA C3    C4     sing N N 229 
GLA C3    O3     sing N N 230 
GLA C3    H3     sing N N 231 
GLA C4    C5     sing N N 232 
GLA C4    O4     sing N N 233 
GLA C4    H4     sing N N 234 
GLA C5    C6     sing N N 235 
GLA C5    O5     sing N N 236 
GLA C5    H5     sing N N 237 
GLA C6    O6     sing N N 238 
GLA C6    H61    sing N N 239 
GLA C6    H62    sing N N 240 
GLA O1    HO1    sing N N 241 
GLA O2    HO2    sing N N 242 
GLA O3    HO3    sing N N 243 
GLA O4    HO4    sing N N 244 
GLA O6    HO6    sing N N 245 
GLN N     CA     sing N N 246 
GLN N     H      sing N N 247 
GLN N     H2     sing N N 248 
GLN CA    C      sing N N 249 
GLN CA    CB     sing N N 250 
GLN CA    HA     sing N N 251 
GLN C     O      doub N N 252 
GLN C     OXT    sing N N 253 
GLN CB    CG     sing N N 254 
GLN CB    HB2    sing N N 255 
GLN CB    HB3    sing N N 256 
GLN CG    CD     sing N N 257 
GLN CG    HG2    sing N N 258 
GLN CG    HG3    sing N N 259 
GLN CD    OE1    doub N N 260 
GLN CD    NE2    sing N N 261 
GLN NE2   HE21   sing N N 262 
GLN NE2   HE22   sing N N 263 
GLN OXT   HXT    sing N N 264 
GLU N     CA     sing N N 265 
GLU N     H      sing N N 266 
GLU N     H2     sing N N 267 
GLU CA    C      sing N N 268 
GLU CA    CB     sing N N 269 
GLU CA    HA     sing N N 270 
GLU C     O      doub N N 271 
GLU C     OXT    sing N N 272 
GLU CB    CG     sing N N 273 
GLU CB    HB2    sing N N 274 
GLU CB    HB3    sing N N 275 
GLU CG    CD     sing N N 276 
GLU CG    HG2    sing N N 277 
GLU CG    HG3    sing N N 278 
GLU CD    OE1    doub N N 279 
GLU CD    OE2    sing N N 280 
GLU OE2   HE2    sing N N 281 
GLU OXT   HXT    sing N N 282 
GLY N     CA     sing N N 283 
GLY N     H      sing N N 284 
GLY N     H2     sing N N 285 
GLY CA    C      sing N N 286 
GLY CA    HA2    sing N N 287 
GLY CA    HA3    sing N N 288 
GLY C     O      doub N N 289 
GLY C     OXT    sing N N 290 
GLY OXT   HXT    sing N N 291 
HIS N     CA     sing N N 292 
HIS N     H      sing N N 293 
HIS N     H2     sing N N 294 
HIS CA    C      sing N N 295 
HIS CA    CB     sing N N 296 
HIS CA    HA     sing N N 297 
HIS C     O      doub N N 298 
HIS C     OXT    sing N N 299 
HIS CB    CG     sing N N 300 
HIS CB    HB2    sing N N 301 
HIS CB    HB3    sing N N 302 
HIS CG    ND1    sing Y N 303 
HIS CG    CD2    doub Y N 304 
HIS ND1   CE1    doub Y N 305 
HIS ND1   HD1    sing N N 306 
HIS CD2   NE2    sing Y N 307 
HIS CD2   HD2    sing N N 308 
HIS CE1   NE2    sing Y N 309 
HIS CE1   HE1    sing N N 310 
HIS NE2   HE2    sing N N 311 
HIS OXT   HXT    sing N N 312 
HOH O     H1     sing N N 313 
HOH O     H2     sing N N 314 
ILE N     CA     sing N N 315 
ILE N     H      sing N N 316 
ILE N     H2     sing N N 317 
ILE CA    C      sing N N 318 
ILE CA    CB     sing N N 319 
ILE CA    HA     sing N N 320 
ILE C     O      doub N N 321 
ILE C     OXT    sing N N 322 
ILE CB    CG1    sing N N 323 
ILE CB    CG2    sing N N 324 
ILE CB    HB     sing N N 325 
ILE CG1   CD1    sing N N 326 
ILE CG1   HG12   sing N N 327 
ILE CG1   HG13   sing N N 328 
ILE CG2   HG21   sing N N 329 
ILE CG2   HG22   sing N N 330 
ILE CG2   HG23   sing N N 331 
ILE CD1   HD11   sing N N 332 
ILE CD1   HD12   sing N N 333 
ILE CD1   HD13   sing N N 334 
ILE OXT   HXT    sing N N 335 
LEU N     CA     sing N N 336 
LEU N     H      sing N N 337 
LEU N     H2     sing N N 338 
LEU CA    C      sing N N 339 
LEU CA    CB     sing N N 340 
LEU CA    HA     sing N N 341 
LEU C     O      doub N N 342 
LEU C     OXT    sing N N 343 
LEU CB    CG     sing N N 344 
LEU CB    HB2    sing N N 345 
LEU CB    HB3    sing N N 346 
LEU CG    CD1    sing N N 347 
LEU CG    CD2    sing N N 348 
LEU CG    HG     sing N N 349 
LEU CD1   HD11   sing N N 350 
LEU CD1   HD12   sing N N 351 
LEU CD1   HD13   sing N N 352 
LEU CD2   HD21   sing N N 353 
LEU CD2   HD22   sing N N 354 
LEU CD2   HD23   sing N N 355 
LEU OXT   HXT    sing N N 356 
LYS N     CA     sing N N 357 
LYS N     H      sing N N 358 
LYS N     H2     sing N N 359 
LYS CA    C      sing N N 360 
LYS CA    CB     sing N N 361 
LYS CA    HA     sing N N 362 
LYS C     O      doub N N 363 
LYS C     OXT    sing N N 364 
LYS CB    CG     sing N N 365 
LYS CB    HB2    sing N N 366 
LYS CB    HB3    sing N N 367 
LYS CG    CD     sing N N 368 
LYS CG    HG2    sing N N 369 
LYS CG    HG3    sing N N 370 
LYS CD    CE     sing N N 371 
LYS CD    HD2    sing N N 372 
LYS CD    HD3    sing N N 373 
LYS CE    NZ     sing N N 374 
LYS CE    HE2    sing N N 375 
LYS CE    HE3    sing N N 376 
LYS NZ    HZ1    sing N N 377 
LYS NZ    HZ2    sing N N 378 
LYS NZ    HZ3    sing N N 379 
LYS OXT   HXT    sing N N 380 
MAN C1    C2     sing N N 381 
MAN C1    O1     sing N N 382 
MAN C1    O5     sing N N 383 
MAN C1    H1     sing N N 384 
MAN C2    C3     sing N N 385 
MAN C2    O2     sing N N 386 
MAN C2    H2     sing N N 387 
MAN C3    C4     sing N N 388 
MAN C3    O3     sing N N 389 
MAN C3    H3     sing N N 390 
MAN C4    C5     sing N N 391 
MAN C4    O4     sing N N 392 
MAN C4    H4     sing N N 393 
MAN C5    C6     sing N N 394 
MAN C5    O5     sing N N 395 
MAN C5    H5     sing N N 396 
MAN C6    O6     sing N N 397 
MAN C6    H61    sing N N 398 
MAN C6    H62    sing N N 399 
MAN O1    HO1    sing N N 400 
MAN O2    HO2    sing N N 401 
MAN O3    HO3    sing N N 402 
MAN O4    HO4    sing N N 403 
MAN O6    HO6    sing N N 404 
MET N     CA     sing N N 405 
MET N     H      sing N N 406 
MET N     H2     sing N N 407 
MET CA    C      sing N N 408 
MET CA    CB     sing N N 409 
MET CA    HA     sing N N 410 
MET C     O      doub N N 411 
MET C     OXT    sing N N 412 
MET CB    CG     sing N N 413 
MET CB    HB2    sing N N 414 
MET CB    HB3    sing N N 415 
MET CG    SD     sing N N 416 
MET CG    HG2    sing N N 417 
MET CG    HG3    sing N N 418 
MET SD    CE     sing N N 419 
MET CE    HE1    sing N N 420 
MET CE    HE2    sing N N 421 
MET CE    HE3    sing N N 422 
MET OXT   HXT    sing N N 423 
NAG C1    C2     sing N N 424 
NAG C1    O1     sing N N 425 
NAG C1    O5     sing N N 426 
NAG C1    H1     sing N N 427 
NAG C2    C3     sing N N 428 
NAG C2    N2     sing N N 429 
NAG C2    H2     sing N N 430 
NAG C3    C4     sing N N 431 
NAG C3    O3     sing N N 432 
NAG C3    H3     sing N N 433 
NAG C4    C5     sing N N 434 
NAG C4    O4     sing N N 435 
NAG C4    H4     sing N N 436 
NAG C5    C6     sing N N 437 
NAG C5    O5     sing N N 438 
NAG C5    H5     sing N N 439 
NAG C6    O6     sing N N 440 
NAG C6    H61    sing N N 441 
NAG C6    H62    sing N N 442 
NAG C7    C8     sing N N 443 
NAG C7    N2     sing N N 444 
NAG C7    O7     doub N N 445 
NAG C8    H81    sing N N 446 
NAG C8    H82    sing N N 447 
NAG C8    H83    sing N N 448 
NAG N2    HN2    sing N N 449 
NAG O1    HO1    sing N N 450 
NAG O3    HO3    sing N N 451 
NAG O4    HO4    sing N N 452 
NAG O6    HO6    sing N N 453 
NGA C1    C2     sing N N 454 
NGA C1    O1     sing N N 455 
NGA C1    O5     sing N N 456 
NGA C1    H1     sing N N 457 
NGA C2    C3     sing N N 458 
NGA C2    N2     sing N N 459 
NGA C2    H2     sing N N 460 
NGA C3    C4     sing N N 461 
NGA C3    O3     sing N N 462 
NGA C3    H3     sing N N 463 
NGA C4    C5     sing N N 464 
NGA C4    O4     sing N N 465 
NGA C4    H4     sing N N 466 
NGA C5    C6     sing N N 467 
NGA C5    O5     sing N N 468 
NGA C5    H5     sing N N 469 
NGA C6    O6     sing N N 470 
NGA C6    H61    sing N N 471 
NGA C6    H62    sing N N 472 
NGA C7    C8     sing N N 473 
NGA C7    N2     sing N N 474 
NGA C7    O7     doub N N 475 
NGA C8    H81    sing N N 476 
NGA C8    H82    sing N N 477 
NGA C8    H83    sing N N 478 
NGA N2    HN2    sing N N 479 
NGA O1    HO1    sing N N 480 
NGA O3    HO3    sing N N 481 
NGA O4    HO4    sing N N 482 
NGA O6    HO6    sing N N 483 
PHE N     CA     sing N N 484 
PHE N     H      sing N N 485 
PHE N     H2     sing N N 486 
PHE CA    C      sing N N 487 
PHE CA    CB     sing N N 488 
PHE CA    HA     sing N N 489 
PHE C     O      doub N N 490 
PHE C     OXT    sing N N 491 
PHE CB    CG     sing N N 492 
PHE CB    HB2    sing N N 493 
PHE CB    HB3    sing N N 494 
PHE CG    CD1    doub Y N 495 
PHE CG    CD2    sing Y N 496 
PHE CD1   CE1    sing Y N 497 
PHE CD1   HD1    sing N N 498 
PHE CD2   CE2    doub Y N 499 
PHE CD2   HD2    sing N N 500 
PHE CE1   CZ     doub Y N 501 
PHE CE1   HE1    sing N N 502 
PHE CE2   CZ     sing Y N 503 
PHE CE2   HE2    sing N N 504 
PHE CZ    HZ     sing N N 505 
PHE OXT   HXT    sing N N 506 
PRO N     CA     sing N N 507 
PRO N     CD     sing N N 508 
PRO N     H      sing N N 509 
PRO CA    C      sing N N 510 
PRO CA    CB     sing N N 511 
PRO CA    HA     sing N N 512 
PRO C     O      doub N N 513 
PRO C     OXT    sing N N 514 
PRO CB    CG     sing N N 515 
PRO CB    HB2    sing N N 516 
PRO CB    HB3    sing N N 517 
PRO CG    CD     sing N N 518 
PRO CG    HG2    sing N N 519 
PRO CG    HG3    sing N N 520 
PRO CD    HD2    sing N N 521 
PRO CD    HD3    sing N N 522 
PRO OXT   HXT    sing N N 523 
SER N     CA     sing N N 524 
SER N     H      sing N N 525 
SER N     H2     sing N N 526 
SER CA    C      sing N N 527 
SER CA    CB     sing N N 528 
SER CA    HA     sing N N 529 
SER C     O      doub N N 530 
SER C     OXT    sing N N 531 
SER CB    OG     sing N N 532 
SER CB    HB2    sing N N 533 
SER CB    HB3    sing N N 534 
SER OG    HG     sing N N 535 
SER OXT   HXT    sing N N 536 
THR N     CA     sing N N 537 
THR N     H      sing N N 538 
THR N     H2     sing N N 539 
THR CA    C      sing N N 540 
THR CA    CB     sing N N 541 
THR CA    HA     sing N N 542 
THR C     O      doub N N 543 
THR C     OXT    sing N N 544 
THR CB    OG1    sing N N 545 
THR CB    CG2    sing N N 546 
THR CB    HB     sing N N 547 
THR OG1   HG1    sing N N 548 
THR CG2   HG21   sing N N 549 
THR CG2   HG22   sing N N 550 
THR CG2   HG23   sing N N 551 
THR OXT   HXT    sing N N 552 
TRP N     CA     sing N N 553 
TRP N     H      sing N N 554 
TRP N     H2     sing N N 555 
TRP CA    C      sing N N 556 
TRP CA    CB     sing N N 557 
TRP CA    HA     sing N N 558 
TRP C     O      doub N N 559 
TRP C     OXT    sing N N 560 
TRP CB    CG     sing N N 561 
TRP CB    HB2    sing N N 562 
TRP CB    HB3    sing N N 563 
TRP CG    CD1    doub Y N 564 
TRP CG    CD2    sing Y N 565 
TRP CD1   NE1    sing Y N 566 
TRP CD1   HD1    sing N N 567 
TRP CD2   CE2    doub Y N 568 
TRP CD2   CE3    sing Y N 569 
TRP NE1   CE2    sing Y N 570 
TRP NE1   HE1    sing N N 571 
TRP CE2   CZ2    sing Y N 572 
TRP CE3   CZ3    doub Y N 573 
TRP CE3   HE3    sing N N 574 
TRP CZ2   CH2    doub Y N 575 
TRP CZ2   HZ2    sing N N 576 
TRP CZ3   CH2    sing Y N 577 
TRP CZ3   HZ3    sing N N 578 
TRP CH2   HH2    sing N N 579 
TRP OXT   HXT    sing N N 580 
TYR N     CA     sing N N 581 
TYR N     H      sing N N 582 
TYR N     H2     sing N N 583 
TYR CA    C      sing N N 584 
TYR CA    CB     sing N N 585 
TYR CA    HA     sing N N 586 
TYR C     O      doub N N 587 
TYR C     OXT    sing N N 588 
TYR CB    CG     sing N N 589 
TYR CB    HB2    sing N N 590 
TYR CB    HB3    sing N N 591 
TYR CG    CD1    doub Y N 592 
TYR CG    CD2    sing Y N 593 
TYR CD1   CE1    sing Y N 594 
TYR CD1   HD1    sing N N 595 
TYR CD2   CE2    doub Y N 596 
TYR CD2   HD2    sing N N 597 
TYR CE1   CZ     doub Y N 598 
TYR CE1   HE1    sing N N 599 
TYR CE2   CZ     sing Y N 600 
TYR CE2   HE2    sing N N 601 
TYR CZ    OH     sing N N 602 
TYR OH    HH     sing N N 603 
TYR OXT   HXT    sing N N 604 
UDP N1    C2     sing N N 605 
UDP N1    C6     sing N N 606 
UDP N1    "C1'"  sing N N 607 
UDP C2    N3     sing N N 608 
UDP C2    O2     doub N N 609 
UDP N3    C4     sing N N 610 
UDP N3    HN3    sing N N 611 
UDP C4    C5     sing N N 612 
UDP C4    O4     doub N N 613 
UDP C5    C6     doub N N 614 
UDP C5    H5     sing N N 615 
UDP C6    H6     sing N N 616 
UDP "C1'" "C2'"  sing N N 617 
UDP "C1'" "O4'"  sing N N 618 
UDP "C1'" "H1'"  sing N N 619 
UDP "C2'" "O2'"  sing N N 620 
UDP "C2'" "C3'"  sing N N 621 
UDP "C2'" "H2'"  sing N N 622 
UDP "O2'" "HO2'" sing N N 623 
UDP "C3'" "C4'"  sing N N 624 
UDP "C3'" "O3'"  sing N N 625 
UDP "C3'" "H3'"  sing N N 626 
UDP "C4'" "O4'"  sing N N 627 
UDP "C4'" "C5'"  sing N N 628 
UDP "C4'" "H4'"  sing N N 629 
UDP "O3'" "HO3'" sing N N 630 
UDP "C5'" "O5'"  sing N N 631 
UDP "C5'" "H5'1" sing N N 632 
UDP "C5'" "H5'2" sing N N 633 
UDP "O5'" PA     sing N N 634 
UDP PA    O1A    doub N N 635 
UDP PA    O2A    sing N N 636 
UDP PA    O3A    sing N N 637 
UDP O2A   HOA2   sing N N 638 
UDP O3A   PB     sing N N 639 
UDP PB    O1B    doub N N 640 
UDP PB    O2B    sing N N 641 
UDP PB    O3B    sing N N 642 
UDP O2B   HOB2   sing N N 643 
UDP O3B   HOB3   sing N N 644 
VAL N     CA     sing N N 645 
VAL N     H      sing N N 646 
VAL N     H2     sing N N 647 
VAL CA    C      sing N N 648 
VAL CA    CB     sing N N 649 
VAL CA    HA     sing N N 650 
VAL C     O      doub N N 651 
VAL C     OXT    sing N N 652 
VAL CB    CG1    sing N N 653 
VAL CB    CG2    sing N N 654 
VAL CB    HB     sing N N 655 
VAL CG1   HG11   sing N N 656 
VAL CG1   HG12   sing N N 657 
VAL CG1   HG13   sing N N 658 
VAL CG2   HG21   sing N N 659 
VAL CG2   HG22   sing N N 660 
VAL CG2   HG23   sing N N 661 
VAL OXT   HXT    sing N N 662 
# 
_pdbx_audit_support.funding_organization   'Academia Sinica (Taiwan)' 
_pdbx_audit_support.country                Taiwan 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 BGC 1 n 
2 GAL 2 n 
2 GLA 3 n 
2 NGA 4 n 
3 NAG 1 n 
3 NAG 2 n 
4 NAG 1 n 
4 NAG 2 n 
4 FUC 3 n 
5 NAG 1 n 
5 NAG 2 n 
5 BMA 3 n 
5 MAN 4 n 
5 MAN 5 n 
5 FUC 6 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          
'Sulfur-SAD was used to solve initial phase with 20 sulfur containing atoms found in one asymmetric unit' 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8ZWP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.020988 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.002010 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011579 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011522 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345  0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
MN ? ? 20.23591 4.67902 ? ? 2.76514  44.01191 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135  5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N      . GLY A 1  12  ? 9.98435   20.05421  24.01011  1.000 58.46590  ? 42  GLY A N      1 
ATOM   2    C  CA     . GLY A 1  12  ? 11.20933  20.42184  24.69439  1.000 54.85894  ? 42  GLY A CA     1 
ATOM   3    C  C      . GLY A 1  12  ? 12.46958  19.79483  24.12885  1.000 49.42994  ? 42  GLY A C      1 
ATOM   4    O  O      . GLY A 1  12  ? 13.32618  19.33497  24.88376  1.000 62.71520  ? 42  GLY A O      1 
ATOM   5    N  N      . ASN A 1  13  ? 12.57314  19.75332  22.80106  1.000 48.16090  ? 43  ASN A N      1 
ATOM   6    C  CA     . ASN A 1  13  ? 13.81231  19.36955  22.13354  1.000 47.83556  ? 43  ASN A CA     1 
ATOM   7    C  C      . ASN A 1  13  ? 13.95020  17.85135  22.00653  1.000 39.86324  ? 43  ASN A C      1 
ATOM   8    O  O      . ASN A 1  13  ? 15.07042  17.33390  22.04140  1.000 41.87383  ? 43  ASN A O      1 
ATOM   9    C  CB     . ASN A 1  13  ? 15.02724  19.90336  22.90369  1.000 52.47228  ? 43  ASN A CB     1 
ATOM   10   C  CG     . ASN A 1  13  ? 15.11117  21.41779  22.90735  1.000 69.35682  ? 43  ASN A CG     1 
ATOM   11   O  OD1    . ASN A 1  13  ? 14.48171  22.09886  22.09212  1.000 61.36333  ? 43  ASN A OD1    1 
ATOM   12   N  ND2    . ASN A 1  13  ? 15.88593  21.95659  23.85028  1.000 66.96378  ? 43  ASN A ND2    1 
ATOM   13   N  N      . PHE A 1  14  ? 12.84759  17.11941  21.86154  1.000 35.07671  ? 44  PHE A N      1 
ATOM   14   C  CA     . PHE A 1  14  ? 12.91596  15.65627  21.84561  1.000 32.36674  ? 44  PHE A CA     1 
ATOM   15   C  C      . PHE A 1  14  ? 13.18709  15.17765  20.42606  1.000 40.82689  ? 44  PHE A C      1 
ATOM   16   O  O      . PHE A 1  14  ? 12.55415  15.65000  19.47461  1.000 44.76021  ? 44  PHE A O      1 
ATOM   17   C  CB     . PHE A 1  14  ? 11.61341  15.03201  22.36759  1.000 26.37208  ? 44  PHE A CB     1 
ATOM   18   C  CG     . PHE A 1  14  ? 11.43585  15.13837  23.86509  1.000 34.32588  ? 44  PHE A CG     1 
ATOM   19   C  CD1    . PHE A 1  14  ? 10.93189  16.28945  24.45468  1.000 32.63095  ? 44  PHE A CD1    1 
ATOM   20   C  CD2    . PHE A 1  14  ? 11.76012  14.06221  24.68563  1.000 31.74915  ? 44  PHE A CD2    1 
ATOM   21   C  CE1    . PHE A 1  14  ? 10.76721  16.37684  25.83297  1.000 34.28700  ? 44  PHE A CE1    1 
ATOM   22   C  CE2    . PHE A 1  14  ? 11.59484  14.14263  26.06249  1.000 22.72263  ? 44  PHE A CE2    1 
ATOM   23   C  CZ     . PHE A 1  14  ? 11.10849  15.28846  26.64154  1.000 29.22377  ? 44  PHE A CZ     1 
ATOM   24   N  N      . LEU A 1  15  ? 14.13566  14.24544  20.28498  1.000 35.99953  ? 45  LEU A N      1 
ATOM   25   C  CA     . LEU A 1  15  ? 14.40288  13.64824  18.97806  1.000 39.53798  ? 45  LEU A CA     1 
ATOM   26   C  C      . LEU A 1  15  ? 13.40594  12.54173  18.65760  1.000 41.64195  ? 45  LEU A C      1 
ATOM   27   O  O      . LEU A 1  15  ? 13.01222  12.36994  17.49649  1.000 42.74893  ? 45  LEU A O      1 
ATOM   28   C  CB     . LEU A 1  15  ? 15.83280  13.10633  18.91853  1.000 35.43408  ? 45  LEU A CB     1 
ATOM   29   C  CG     . LEU A 1  15  ? 16.92619  14.00844  19.47218  1.000 39.50501  ? 45  LEU A CG     1 
ATOM   30   C  CD1    . LEU A 1  15  ? 18.28919  13.40588  19.14792  1.000 39.31066  ? 45  LEU A CD1    1 
ATOM   31   C  CD2    . LEU A 1  15  ? 16.79510  15.41221  18.89961  1.000 49.88700  ? 45  LEU A CD2    1 
ATOM   32   N  N      . LYS A 1  16  ? 12.98226  11.78830  19.66858  1.000 33.23964  ? 46  LYS A N      1 
ATOM   33   C  CA     . LYS A 1  16  ? 11.96675  10.75591  19.51655  1.000 31.70059  ? 46  LYS A CA     1 
ATOM   34   C  C      . LYS A 1  16  ? 10.91927  10.89051  20.60959  1.000 30.33492  ? 46  LYS A C      1 
ATOM   35   O  O      . LYS A 1  16  ? 11.25219  11.09982  21.78365  1.000 32.28965  ? 46  LYS A O      1 
ATOM   36   C  CB     . LYS A 1  16  ? 12.60761  9.35513   19.55293  1.000 32.10585  ? 46  LYS A CB     1 
ATOM   37   C  CG     . LYS A 1  16  ? 13.54236  9.10764   18.37948  1.000 35.90208  ? 46  LYS A CG     1 
ATOM   38   C  CD     . LYS A 1  16  ? 14.14078  7.71140   18.39434  1.000 38.88847  ? 46  LYS A CD     1 
ATOM   39   C  CE     . LYS A 1  16  ? 14.87910  7.42684   17.09091  1.000 37.14816  ? 46  LYS A CE     1 
ATOM   40   N  NZ     . LYS A 1  16  ? 15.99812  8.39283   16.87429  1.000 40.36962  ? 46  LYS A NZ     1 
ATOM   41   N  N      . LEU A 1  17  ? 9.65441   10.77922  20.21408  1.000 32.05167  ? 47  LEU A N      1 
ATOM   42   C  CA     . LEU A 1  17  ? 8.51542   10.82859  21.11572  1.000 32.15335  ? 47  LEU A CA     1 
ATOM   43   C  C      . LEU A 1  17  ? 7.66661   9.58625   20.87044  1.000 32.59213  ? 47  LEU A C      1 
ATOM   44   O  O      . LEU A 1  17  ? 7.31920   9.29741   19.70939  1.000 35.15826  ? 47  LEU A O      1 
ATOM   45   C  CB     . LEU A 1  17  ? 7.67337   12.08863  20.89055  1.000 29.43622  ? 47  LEU A CB     1 
ATOM   46   C  CG     . LEU A 1  17  ? 8.18704   13.41984  21.44987  1.000 31.19228  ? 47  LEU A CG     1 
ATOM   47   C  CD1    . LEU A 1  17  ? 7.18232   14.50369  21.10641  1.000 33.73958  ? 47  LEU A CD1    1 
ATOM   48   C  CD2    . LEU A 1  17  ? 8.45156   13.36248  22.95032  1.000 31.50529  ? 47  LEU A CD2    1 
ATOM   49   N  N      . PRO A 1  18  ? 7.27318   8.85185   21.91637  1.000 32.71258  ? 48  PRO A N      1 
ATOM   50   C  CA     . PRO A 1  18  ? 6.40071   7.68155   21.70929  1.000 33.36386  ? 48  PRO A CA     1 
ATOM   51   C  C      . PRO A 1  18  ? 5.04200   8.06235   21.14672  1.000 39.28204  ? 48  PRO A C      1 
ATOM   52   O  O      . PRO A 1  18  ? 4.45925   9.09282   21.50731  1.000 31.78475  ? 48  PRO A O      1 
ATOM   53   C  CB     . PRO A 1  18  ? 6.23990   7.08329   23.11288  1.000 29.36999  ? 48  PRO A CB     1 
ATOM   54   C  CG     . PRO A 1  18  ? 7.27275   7.74571   23.96067  1.000 36.29242  ? 48  PRO A CG     1 
ATOM   55   C  CD     . PRO A 1  18  ? 7.60208   9.06709   23.33302  1.000 35.06792  ? 48  PRO A CD     1 
ATOM   56   N  N      . ASP A 1  19  ? 4.52350   7.17281   20.29104  1.000 43.88449  ? 49  ASP A N      1 
ATOM   57   C  CA     . ASP A 1  19  ? 3.21501   7.32219   19.65954  1.000 47.89419  ? 49  ASP A CA     1 
ATOM   58   C  C      . ASP A 1  19  ? 2.14563   6.93682   20.67101  1.000 47.99170  ? 49  ASP A C      1 
ATOM   59   O  O      . ASP A 1  19  ? 1.53839   5.86353   20.61800  1.000 45.94953  ? 49  ASP A O      1 
ATOM   60   C  CB     . ASP A 1  19  ? 3.12852   6.44605   18.41094  1.000 59.80419  ? 49  ASP A CB     1 
ATOM   61   C  CG     . ASP A 1  19  ? 1.79483   6.58641   17.67059  1.000 73.47674  ? 49  ASP A CG     1 
ATOM   62   O  OD1    . ASP A 1  19  ? 0.85515   7.20736   18.21574  1.000 63.00782  ? 49  ASP A OD1    1 
ATOM   63   O  OD2    . ASP A 1  19  ? 1.67581   6.04791   16.54534  1.000 85.47239  ? 49  ASP A OD2    1 
ATOM   64   N  N      . THR A 1  20  ? 1.89298   7.85215   21.59594  1.000 40.95550  ? 50  THR A N      1 
ATOM   65   C  CA     . THR A 1  20  ? 0.93419   7.59445   22.65133  1.000 45.22099  ? 50  THR A CA     1 
ATOM   66   C  C      . THR A 1  20  ? 0.27132   8.91373   22.99417  1.000 41.71697  ? 50  THR A C      1 
ATOM   67   O  O      . THR A 1  20  ? 0.91050   9.96408   22.93288  1.000 45.14667  ? 50  THR A O      1 
ATOM   68   C  CB     . THR A 1  20  ? 1.60679   6.99215   23.88875  1.000 41.71903  ? 50  THR A CB     1 
ATOM   69   O  OG1    . THR A 1  20  ? 0.61756   6.35459   24.70651  1.000 46.82682  ? 50  THR A OG1    1 
ATOM   70   C  CG2    . THR A 1  20  ? 2.26581   8.10687   24.69550  1.000 38.76167  ? 50  THR A CG2    1 
ATOM   71   N  N      . ASP A 1  21  ? -0.98334  8.84023   23.44423  1.000 41.04612  ? 51  ASP A N      1 
ATOM   72   C  CA     . ASP A 1  21  ? -1.81501  10.00864  23.74506  1.000 41.66281  ? 51  ASP A CA     1 
ATOM   73   C  C      . ASP A 1  21  ? -2.42691  9.85627   25.13588  1.000 48.59719  ? 51  ASP A C      1 
ATOM   74   O  O      . ASP A 1  21  ? -3.51824  9.30259   25.28420  1.000 49.69012  ? 51  ASP A O      1 
ATOM   75   C  CB     . ASP A 1  21  ? -2.89453  10.16511  22.66665  1.000 56.91010  ? 51  ASP A CB     1 
ATOM   76   C  CG     . ASP A 1  21  ? -3.72674  11.42668  22.83469  1.000 64.92348  ? 51  ASP A CG     1 
ATOM   77   O  OD1    . ASP A 1  21  ? -4.10439  11.76061  23.98103  1.000 64.96555  ? 51  ASP A OD1    1 
ATOM   78   O  OD2    . ASP A 1  21  ? -4.01186  12.08126  21.80749  1.000 71.72188  ? 51  ASP A OD2    1 
ATOM   79   N  N      . CYS A 1  22  ? -1.74147  10.38434  26.15561  1.000 36.88474  ? 52  CYS A N      1 
ATOM   80   C  CA     . CYS A 1  22  ? -2.19956  10.20796  27.53005  1.000 39.97490  ? 52  CYS A CA     1 
ATOM   81   C  C      . CYS A 1  22  ? -3.45768  10.99469  27.85500  1.000 39.86021  ? 52  CYS A C      1 
ATOM   82   O  O      . CYS A 1  22  ? -4.13716  10.67126  28.83633  1.000 38.83379  ? 52  CYS A O      1 
ATOM   83   C  CB     . CYS A 1  22  ? -1.09758  10.62123  28.50945  1.000 38.29013  ? 52  CYS A CB     1 
ATOM   84   S  SG     . CYS A 1  22  ? 0.36108   9.61123   28.36812  1.000 41.86655  ? 52  CYS A SG     1 
ATOM   85   N  N      . ARG A 1  23  ? -3.77284  12.03708  27.08910  1.000 51.00530  ? 53  ARG A N      1 
ATOM   86   C  CA     . ARG A 1  23  ? -5.02026  12.75337  27.32887  1.000 57.46855  ? 53  ARG A CA     1 
ATOM   87   C  C      . ARG A 1  23  ? -6.20574  11.87008  26.96804  1.000 58.46820  ? 53  ARG A C      1 
ATOM   88   O  O      . ARG A 1  23  ? -7.17543  11.76253  27.72907  1.000 56.40908  ? 53  ARG A O      1 
ATOM   89   C  CB     . ARG A 1  23  ? -5.04683  14.05565  26.52639  1.000 60.37478  ? 53  ARG A CB     1 
ATOM   90   C  CG     . ARG A 1  23  ? -6.12309  15.03450  26.96390  1.000 75.20450  ? 53  ARG A CG     1 
ATOM   91   C  CD     . ARG A 1  23  ? -6.91871  15.56602  25.77672  1.000 84.28305  ? 53  ARG A CD     1 
ATOM   92   N  NE     . ARG A 1  23  ? -7.51144  14.47712  25.00852  1.000 89.66697  ? 53  ARG A NE     1 
ATOM   93   C  CZ     . ARG A 1  23  ? -7.99448  14.59472  23.77925  1.000 90.58058  ? 53  ARG A CZ     1 
ATOM   94   N  NH1    . ARG A 1  23  ? -7.98298  15.75351  23.13889  1.000 94.70748  ? 53  ARG A NH1    1 
ATOM   95   N  NH2    . ARG A 1  23  ? -8.49982  13.52146  23.17648  1.000 83.80259  ? 53  ARG A NH2    1 
ATOM   96   N  N      . GLN A 1  24  ? -6.12099  11.20510  25.81378  1.000 56.27924  ? 54  GLN A N      1 
ATOM   97   C  CA     . GLN A 1  24  ? -7.17874  10.30273  25.37679  1.000 67.13539  ? 54  GLN A CA     1 
ATOM   98   C  C      . GLN A 1  24  ? -7.32311  9.13086   26.34300  1.000 67.86237  ? 54  GLN A C      1 
ATOM   99   O  O      . GLN A 1  24  ? -8.41910  8.85121   26.84628  1.000 65.98800  ? 54  GLN A O      1 
ATOM   100  C  CB     . GLN A 1  24  ? -6.84999  9.80212   23.96462  1.000 73.02023  ? 54  GLN A CB     1 
ATOM   101  C  CG     . GLN A 1  24  ? -7.93397  9.00054   23.25634  1.000 76.83275  ? 54  GLN A CG     1 
ATOM   102  C  CD     . GLN A 1  24  ? -8.92364  9.89859   22.52284  1.000 83.67049  ? 54  GLN A CD     1 
ATOM   103  O  OE1    . GLN A 1  24  ? -8.59304  11.02609  22.14798  1.000 80.27809  ? 54  GLN A OE1    1 
ATOM   104  N  NE2    . GLN A 1  24  ? -10.13685 9.39970   22.30832  1.000 76.41813  ? 54  GLN A NE2    1 
ATOM   105  N  N      . THR A 1  25  ? -6.21362  8.44070   26.62016  1.000 61.41252  ? 55  THR A N      1 
ATOM   106  C  CA     . THR A 1  25  ? -6.18042  7.25775   27.48013  1.000 60.72929  ? 55  THR A CA     1 
ATOM   107  C  C      . THR A 1  25  ? -5.15216  7.45368   28.58823  1.000 48.33852  ? 55  THR A C      1 
ATOM   108  O  O      . THR A 1  25  ? -4.00758  7.00195   28.46679  1.000 45.21289  ? 55  THR A O      1 
ATOM   109  C  CB     . THR A 1  25  ? -5.86442  6.00860   26.66140  1.000 66.00859  ? 55  THR A CB     1 
ATOM   110  O  OG1    . THR A 1  25  ? -4.70718  6.25359   25.84980  1.000 70.47266  ? 55  THR A OG1    1 
ATOM   111  C  CG2    . THR A 1  25  ? -7.03678  5.65484   25.75684  1.000 74.64355  ? 55  THR A CG2    1 
ATOM   112  N  N      . PRO A 1  26  ? -5.52700  8.09792   29.68799  1.000 42.66097  ? 56  PRO A N      1 
ATOM   113  C  CA     . PRO A 1  26  ? -4.58109  8.29653   30.80019  1.000 40.93350  ? 56  PRO A CA     1 
ATOM   114  C  C      . PRO A 1  26  ? -4.07220  6.96330   31.32042  1.000 45.07848  ? 56  PRO A C      1 
ATOM   115  O  O      . PRO A 1  26  ? -4.86642  6.09150   31.70660  1.000 36.88483  ? 56  PRO A O      1 
ATOM   116  C  CB     . PRO A 1  26  ? -5.42467  9.01289   31.86487  1.000 42.76245  ? 56  PRO A CB     1 
ATOM   117  C  CG     . PRO A 1  26  ? -6.61281  9.56389   31.12177  1.000 45.28006  ? 56  PRO A CG     1 
ATOM   118  C  CD     . PRO A 1  26  ? -6.87205  8.59246   30.00736  1.000 48.93461  ? 56  PRO A CD     1 
ATOM   119  N  N      . PRO A 1  27  ? -2.75850  6.75220   31.34189  1.000 35.45826  ? 57  PRO A N      1 
ATOM   120  C  CA     . PRO A 1  27  ? -2.24485  5.48725   31.87896  1.000 32.57399  ? 57  PRO A CA     1 
ATOM   121  C  C      . PRO A 1  27  ? -2.31727  5.46744   33.39837  1.000 27.79200  ? 57  PRO A C      1 
ATOM   122  O  O      . PRO A 1  27  ? -2.21754  6.49817   34.06795  1.000 28.95268  ? 57  PRO A O      1 
ATOM   123  C  CB     . PRO A 1  27  ? -0.79735  5.43961   31.37127  1.000 30.35008  ? 57  PRO A CB     1 
ATOM   124  C  CG     . PRO A 1  27  ? -0.42863  6.84507   31.10315  1.000 32.90856  ? 57  PRO A CG     1 
ATOM   125  C  CD     . PRO A 1  27  ? -1.69669  7.59934   30.76887  1.000 35.19780  ? 57  PRO A CD     1 
ATOM   126  N  N      . PHE A 1  28  ? -2.50358  4.27145   33.94833  1.000 22.79841  ? 58  PHE A N      1 
ATOM   127  C  CA     . PHE A 1  28  ? -2.40254  4.14245   35.38897  1.000 25.16982  ? 58  PHE A CA     1 
ATOM   128  C  C      . PHE A 1  28  ? -0.94793  4.07066   35.81147  1.000 28.31247  ? 58  PHE A C      1 
ATOM   129  O  O      . PHE A 1  28  ? -0.56654  4.66412   36.82610  1.000 23.44281  ? 58  PHE A O      1 
ATOM   130  C  CB     . PHE A 1  28  ? -3.14004  2.90527   35.88917  1.000 21.11444  ? 58  PHE A CB     1 
ATOM   131  C  CG     . PHE A 1  28  ? -2.98890  2.67321   37.36319  1.000 21.96639  ? 58  PHE A CG     1 
ATOM   132  C  CD1    . PHE A 1  28  ? -3.74986  3.39675   38.26603  1.000 23.21707  ? 58  PHE A CD1    1 
ATOM   133  C  CD2    . PHE A 1  28  ? -2.08876  1.73084   37.85282  1.000 19.11045  ? 58  PHE A CD2    1 
ATOM   134  C  CE1    . PHE A 1  28  ? -3.60884  3.19961   39.62479  1.000 27.95428  ? 58  PHE A CE1    1 
ATOM   135  C  CE2    . PHE A 1  28  ? -1.94144  1.53013   39.22638  1.000 24.61862  ? 58  PHE A CE2    1 
ATOM   136  C  CZ     . PHE A 1  28  ? -2.70491  2.26535   40.11242  1.000 26.70698  ? 58  PHE A CZ     1 
ATOM   137  N  N      . LEU A 1  29  ? -0.14303  3.32413   35.06112  1.000 21.60679  ? 59  LEU A N      1 
ATOM   138  C  CA     . LEU A 1  29  ? 1.27126   3.18592   35.39793  1.000 22.33226  ? 59  LEU A CA     1 
ATOM   139  C  C      . LEU A 1  29  ? 2.08522   3.33451   34.12868  1.000 19.53172  ? 59  LEU A C      1 
ATOM   140  O  O      . LEU A 1  29  ? 1.82927   2.65042   33.13295  1.000 21.74119  ? 59  LEU A O      1 
ATOM   141  C  CB     . LEU A 1  29  ? 1.57769   1.82161   36.04944  1.000 20.48446  ? 59  LEU A CB     1 
ATOM   142  C  CG     . LEU A 1  29  ? 3.05530   1.60830   36.44246  1.000 19.84698  ? 59  LEU A CG     1 
ATOM   143  C  CD1    . LEU A 1  29  ? 3.45808   2.58370   37.56124  1.000 21.99839  ? 59  LEU A CD1    1 
ATOM   144  C  CD2    . LEU A 1  29  ? 3.30404   0.17929   36.86331  1.000 20.14268  ? 59  LEU A CD2    1 
ATOM   145  N  N      . VAL A 1  30  ? 3.07466   4.21925   34.17260  1.000 18.56005  ? 60  VAL A N      1 
ATOM   146  C  CA     . VAL A 1  30  ? 4.02663   4.38945   33.08738  1.000 17.99887  ? 60  VAL A CA     1 
ATOM   147  C  C      . VAL A 1  30  ? 5.37987   3.91899   33.59788  1.000 19.43297  ? 60  VAL A C      1 
ATOM   148  O  O      . VAL A 1  30  ? 5.85156   4.42102   34.62483  1.000 20.42235  ? 60  VAL A O      1 
ATOM   149  C  CB     . VAL A 1  30  ? 4.12145   5.85787   32.63166  1.000 23.71131  ? 60  VAL A CB     1 
ATOM   150  C  CG1    . VAL A 1  30  ? 5.33040   6.04248   31.73462  1.000 25.57616  ? 60  VAL A CG1    1 
ATOM   151  C  CG2    . VAL A 1  30  ? 2.84554   6.27170   31.90975  1.000 22.84694  ? 60  VAL A CG2    1 
ATOM   152  N  N      . LEU A 1  31  ? 5.99981   2.98521   32.88409  1.000 19.00855  ? 61  LEU A N      1 
ATOM   153  C  CA     . LEU A 1  31  ? 7.36111   2.52987   33.17439  1.000 20.81623  ? 61  LEU A CA     1 
ATOM   154  C  C      . LEU A 1  31  ? 8.31456   3.26120   32.24418  1.000 19.39799  ? 61  LEU A C      1 
ATOM   155  O  O      . LEU A 1  31  ? 8.09416   3.29823   31.03104  1.000 20.37870  ? 61  LEU A O      1 
ATOM   156  C  CB     . LEU A 1  31  ? 7.50965   1.00817   32.97456  1.000 17.44262  ? 61  LEU A CB     1 
ATOM   157  C  CG     . LEU A 1  31  ? 6.53098   0.14324   33.76683  1.000 22.59014  ? 61  LEU A CG     1 
ATOM   158  C  CD1    . LEU A 1  31  ? 6.64853   -1.32645  33.34936  1.000 28.91594  ? 61  LEU A CD1    1 
ATOM   159  C  CD2    . LEU A 1  31  ? 6.81085   0.28044   35.25242  1.000 23.62051  ? 61  LEU A CD2    1 
ATOM   160  N  N      . LEU A 1  32  ? 9.33765   3.88580   32.82168  1.000 19.86636  ? 62  LEU A N      1 
ATOM   161  C  CA     . LEU A 1  32  ? 10.40706  4.53693   32.08438  1.000 20.65486  ? 62  LEU A CA     1 
ATOM   162  C  C      . LEU A 1  32  ? 11.68177  3.74725   32.35774  1.000 21.45968  ? 62  LEU A C      1 
ATOM   163  O  O      . LEU A 1  32  ? 12.16676  3.75212   33.48941  1.000 18.67057  ? 62  LEU A O      1 
ATOM   164  C  CB     . LEU A 1  32  ? 10.56342  5.97429   32.53970  1.000 16.35242  ? 62  LEU A CB     1 
ATOM   165  C  CG     . LEU A 1  32  ? 9.32381   6.86372   32.48597  1.000 22.34422  ? 62  LEU A CG     1 
ATOM   166  C  CD1    . LEU A 1  32  ? 9.67480   8.19703   33.11840  1.000 23.56618  ? 62  LEU A CD1    1 
ATOM   167  C  CD2    . LEU A 1  32  ? 8.91782   7.01956   31.03226  1.000 24.27111  ? 62  LEU A CD2    1 
ATOM   168  N  N      . VAL A 1  33  ? 12.21181  3.07362   31.33424  1.000 17.77597  ? 63  VAL A N      1 
ATOM   169  C  CA     . VAL A 1  33  ? 13.30892  2.11943   31.49919  1.000 21.59049  ? 63  VAL A CA     1 
ATOM   170  C  C      . VAL A 1  33  ? 14.58107  2.72949   30.92374  1.000 20.28995  ? 63  VAL A C      1 
ATOM   171  O  O      . VAL A 1  33  ? 14.61375  3.10960   29.74787  1.000 23.31063  ? 63  VAL A O      1 
ATOM   172  C  CB     . VAL A 1  33  ? 13.00304  0.78390   30.80339  1.000 21.52276  ? 63  VAL A CB     1 
ATOM   173  C  CG1    . VAL A 1  33  ? 14.18655  -0.18821  30.98712  1.000 19.45619  ? 63  VAL A CG1    1 
ATOM   174  C  CG2    . VAL A 1  33  ? 11.68848  0.19406   31.31258  1.000 24.55430  ? 63  VAL A CG2    1 
ATOM   175  N  N      . THR A 1  34  ? 15.62943  2.79632   31.73150  1.000 19.86889  ? 64  THR A N      1 
ATOM   176  C  CA     . THR A 1  34  ? 16.92337  3.25188   31.23855  1.000 22.73262  ? 64  THR A CA     1 
ATOM   177  C  C      . THR A 1  34  ? 17.72127  2.08093   30.67012  1.000 28.53475  ? 64  THR A C      1 
ATOM   178  O  O      . THR A 1  34  ? 17.72074  0.97004   31.22691  1.000 28.18939  ? 64  THR A O      1 
ATOM   179  C  CB     . THR A 1  34  ? 17.72703  3.93095   32.34712  1.000 24.16995  ? 64  THR A CB     1 
ATOM   180  O  OG1    . THR A 1  34  ? 17.97366  2.98284   33.38790  1.000 25.33119  ? 64  THR A OG1    1 
ATOM   181  C  CG2    . THR A 1  34  ? 16.95721  5.13033   32.90415  1.000 18.04332  ? 64  THR A CG2    1 
ATOM   182  N  N      . SER A 1  35  ? 18.36568  2.32071   29.53156  1.000 25.65329  ? 65  SER A N      1 
ATOM   183  C  CA     . SER A 1  35  ? 19.28261  1.34654   28.94778  1.000 28.11664  ? 65  SER A CA     1 
ATOM   184  C  C      . SER A 1  35  ? 20.15350  2.08576   27.94355  1.000 28.94853  ? 65  SER A C      1 
ATOM   185  O  O      . SER A 1  35  ? 19.76738  3.13597   27.42879  1.000 25.66519  ? 65  SER A O      1 
ATOM   186  C  CB     . SER A 1  35  ? 18.53358  0.18182   28.27876  1.000 23.27075  ? 65  SER A CB     1 
ATOM   187  O  OG     . SER A 1  35  ? 17.78733  0.60686   27.14880  1.000 26.81364  ? 65  SER A OG     1 
ATOM   188  N  N      . SER A 1  36  ? 21.33269  1.53351   27.67247  1.000 29.19275  ? 66  SER A N      1 
ATOM   189  C  CA     . SER A 1  36  ? 22.20665  2.13437   26.67824  1.000 33.03182  ? 66  SER A CA     1 
ATOM   190  C  C      . SER A 1  36  ? 21.85522  1.59614   25.28373  1.000 31.68494  ? 66  SER A C      1 
ATOM   191  O  O      . SER A 1  36  ? 21.10063  0.63604   25.13522  1.000 33.17337  ? 66  SER A O      1 
ATOM   192  C  CB     . SER A 1  36  ? 23.67014  1.89450   27.04870  1.000 33.27488  ? 66  SER A CB     1 
ATOM   193  O  OG     . SER A 1  36  ? 24.03687  0.53889   26.89136  1.000 42.79936  ? 66  SER A OG     1 
ATOM   194  N  N      . HIS A 1  37  ? 22.41976  2.22566   24.24540  1.000 37.20021  ? 67  HIS A N      1 
ATOM   195  C  CA     . HIS A 1  37  ? 22.04852  1.87969   22.86837  1.000 30.93360  ? 67  HIS A CA     1 
ATOM   196  C  C      . HIS A 1  37  ? 22.28280  0.40668   22.55765  1.000 34.36479  ? 67  HIS A C      1 
ATOM   197  O  O      . HIS A 1  37  ? 21.46006  -0.23460  21.88600  1.000 34.15151  ? 67  HIS A O      1 
ATOM   198  C  CB     . HIS A 1  37  ? 22.84536  2.72891   21.87906  1.000 40.81366  ? 67  HIS A CB     1 
ATOM   199  C  CG     . HIS A 1  37  ? 22.49512  4.17691   21.91285  1.000 37.40810  ? 67  HIS A CG     1 
ATOM   200  N  ND1    . HIS A 1  37  ? 21.84620  4.80977   20.87446  1.000 41.14174  ? 67  HIS A ND1    1 
ATOM   201  C  CD2    . HIS A 1  37  ? 22.67762  5.11075   22.87473  1.000 34.58585  ? 67  HIS A CD2    1 
ATOM   202  C  CE1    . HIS A 1  37  ? 21.65515  6.07706   21.19065  1.000 42.02440  ? 67  HIS A CE1    1 
ATOM   203  N  NE2    . HIS A 1  37  ? 22.15311  6.28588   22.39821  1.000 44.47895  ? 67  HIS A NE2    1 
ATOM   204  N  N      . LYS A 1  38  ? 23.41953  -0.13450  22.99505  1.000 33.78176  ? 68  LYS A N      1 
ATOM   205  C  CA     . LYS A 1  38  ? 23.76518  -1.50557  22.64266  1.000 44.65103  ? 68  LYS A CA     1 
ATOM   206  C  C      . LYS A 1  38  ? 22.89939  -2.53066  23.36657  1.000 41.98710  ? 68  LYS A C      1 
ATOM   207  O  O      . LYS A 1  38  ? 22.88577  -3.69842  22.96125  1.000 38.12993  ? 68  LYS A O      1 
ATOM   208  C  CB     . LYS A 1  38  ? 25.23826  -1.77162  22.94990  1.000 44.72211  ? 68  LYS A CB     1 
ATOM   209  C  CG     . LYS A 1  38  ? 25.56758  -1.69324  24.42838  1.000 43.22301  ? 68  LYS A CG     1 
ATOM   210  C  CD     . LYS A 1  38  ? 27.04858  -1.88370  24.69523  1.000 53.57003  ? 68  LYS A CD     1 
ATOM   211  C  CE     . LYS A 1  38  ? 27.38428  -1.50464  26.13091  1.000 68.01845  ? 68  LYS A CE     1 
ATOM   212  N  NZ     . LYS A 1  38  ? 28.81057  -1.76745  26.46199  1.000 75.61608  ? 68  LYS A NZ     1 
ATOM   213  N  N      . GLN A 1  39  ? 22.18390  -2.12897  24.42483  1.000 36.62918  ? 69  GLN A N      1 
ATOM   214  C  CA     . GLN A 1  39  ? 21.41016  -3.07147  25.23753  1.000 33.62180  ? 69  GLN A CA     1 
ATOM   215  C  C      . GLN A 1  39  ? 20.06425  -3.41829  24.62408  1.000 34.62540  ? 69  GLN A C      1 
ATOM   216  O  O      . GLN A 1  39  ? 19.04653  -3.44709  25.31629  1.000 31.43630  ? 69  GLN A O      1 
ATOM   217  C  CB     . GLN A 1  39  ? 21.24059  -2.51662  26.65037  1.000 29.28358  ? 69  GLN A CB     1 
ATOM   218  C  CG     . GLN A 1  39  ? 22.54520  -2.40932  27.40797  1.000 31.05341  ? 69  GLN A CG     1 
ATOM   219  C  CD     . GLN A 1  39  ? 22.37298  -1.99512  28.85155  1.000 32.25818  ? 69  GLN A CD     1 
ATOM   220  O  OE1    . GLN A 1  39  ? 22.00642  -0.86098  29.13724  1.000 30.93165  ? 69  GLN A OE1    1 
ATOM   221  N  NE2    . GLN A 1  39  ? 22.65624  -2.90732  29.77517  1.000 38.99107  ? 69  GLN A NE2    1 
ATOM   222  N  N      . LEU A 1  40  ? 20.03549  -3.69490  23.31866  1.000 28.56631  ? 70  LEU A N      1 
ATOM   223  C  CA     . LEU A 1  40  ? 18.79352  -4.11023  22.67456  1.000 33.62975  ? 70  LEU A CA     1 
ATOM   224  C  C      . LEU A 1  40  ? 18.24058  -5.40600  23.26946  1.000 29.70096  ? 70  LEU A C      1 
ATOM   225  O  O      . LEU A 1  40  ? 17.02294  -5.56213  23.39595  1.000 32.02271  ? 70  LEU A O      1 
ATOM   226  C  CB     . LEU A 1  40  ? 19.01129  -4.27150  21.17174  1.000 32.81971  ? 70  LEU A CB     1 
ATOM   227  C  CG     . LEU A 1  40  ? 17.77675  -4.80437  20.45707  1.000 35.75609  ? 70  LEU A CG     1 
ATOM   228  C  CD1    . LEU A 1  40  ? 16.58436  -3.88085  20.69991  1.000 36.48969  ? 70  LEU A CD1    1 
ATOM   229  C  CD2    . LEU A 1  40  ? 18.06131  -4.96698  18.96945  1.000 48.51655  ? 70  LEU A CD2    1 
ATOM   230  N  N      . ALA A 1  41  ? 19.10869  -6.35446  23.61963  1.000 32.55526  ? 71  ALA A N      1 
ATOM   231  C  CA     . ALA A 1  41  ? 18.62299  -7.60792  24.20471  1.000 38.29830  ? 71  ALA A CA     1 
ATOM   232  C  C      . ALA A 1  41  ? 17.82645  -7.34750  25.47891  1.000 27.58571  ? 71  ALA A C      1 
ATOM   233  O  O      . ALA A 1  41  ? 16.76878  -7.95552  25.69952  1.000 27.50767  ? 71  ALA A O      1 
ATOM   234  C  CB     . ALA A 1  41  ? 19.79565  -8.55241  24.48810  1.000 31.93193  ? 71  ALA A CB     1 
ATOM   235  N  N      . GLU A 1  42  ? 18.32807  -6.44444  26.32918  1.000 28.84693  ? 72  GLU A N      1 
ATOM   236  C  CA     . GLU A 1  42  ? 17.59721  -6.04112  27.52337  1.000 31.98820  ? 72  GLU A CA     1 
ATOM   237  C  C      . GLU A 1  42  ? 16.21267  -5.53131  27.17016  1.000 25.55633  ? 72  GLU A C      1 
ATOM   238  O  O      . GLU A 1  42  ? 15.20614  -5.94654  27.76392  1.000 25.12182  ? 72  GLU A O      1 
ATOM   239  C  CB     . GLU A 1  42  ? 18.37826  -4.96074  28.28068  1.000 25.28155  ? 72  GLU A CB     1 
ATOM   240  C  CG     . GLU A 1  42  ? 19.46430  -5.49567  29.18820  1.000 32.34815  ? 72  GLU A CG     1 
ATOM   241  C  CD     . GLU A 1  42  ? 20.71544  -5.96970  28.46270  1.000 35.58537  ? 72  GLU A CD     1 
ATOM   242  O  OE1    . GLU A 1  42  ? 20.82121  -5.81743  27.22742  1.000 33.02936  ? 72  GLU A OE1    1 
ATOM   243  O  OE2    . GLU A 1  42  ? 21.59448  -6.51319  29.15334  1.000 34.08990  ? 72  GLU A OE2    1 
ATOM   244  N  N      . ARG A 1  43  ? 16.14323  -4.58911  26.22642  1.000 26.05965  ? 73  ARG A N      1 
ATOM   245  C  CA     . ARG A 1  43  ? 14.85960  -3.98310  25.91572  1.000 23.23028  ? 73  ARG A CA     1 
ATOM   246  C  C      . ARG A 1  43  ? 13.90083  -4.99903  25.31202  1.000 23.11033  ? 73  ARG A C      1 
ATOM   247  O  O      . ARG A 1  43  ? 12.70586  -4.99276  25.62586  1.000 24.80630  ? 73  ARG A O      1 
ATOM   248  C  CB     . ARG A 1  43  ? 15.06166  -2.78536  24.97569  1.000 26.14683  ? 73  ARG A CB     1 
ATOM   249  C  CG     . ARG A 1  43  ? 15.83613  -1.65043  25.61782  1.000 24.51100  ? 73  ARG A CG     1 
ATOM   250  C  CD     . ARG A 1  43  ? 15.77911  -0.35596  24.78685  1.000 30.44341  ? 73  ARG A CD     1 
ATOM   251  N  NE     . ARG A 1  43  ? 16.50276  -0.46508  23.52536  1.000 30.89421  ? 73  ARG A NE     1 
ATOM   252  C  CZ     . ARG A 1  43  ? 17.81454  -0.31635  23.40631  1.000 27.16416  ? 73  ARG A CZ     1 
ATOM   253  N  NH1    . ARG A 1  43  ? 18.58119  -0.08201  24.45609  1.000 27.95662  ? 73  ARG A NH1    1 
ATOM   254  N  NH2    . ARG A 1  43  ? 18.37135  -0.40164  22.20187  1.000 29.47928  ? 73  ARG A NH2    1 
ATOM   255  N  N      . MET A 1  44  ? 14.39713  -5.89144  24.45675  1.000 25.82915  ? 74  MET A N      1 
ATOM   256  C  CA     . MET A 1  44  ? 13.51146  -6.90901  23.89054  1.000 30.17349  ? 74  MET A CA     1 
ATOM   257  C  C      . MET A 1  44  ? 12.98632  -7.84121  24.97909  1.000 26.78709  ? 74  MET A C      1 
ATOM   258  O  O      . MET A 1  44  ? 11.79018  -8.16710  25.00766  1.000 26.69113  ? 74  MET A O      1 
ATOM   259  C  CB     . MET A 1  44  ? 14.22883  -7.70354  22.79642  1.000 28.74486  ? 74  MET A CB     1 
ATOM   260  C  CG     . MET A 1  44  ? 14.54516  -6.92214  21.52445  1.000 30.20488  ? 74  MET A CG     1 
ATOM   261  S  SD     . MET A 1  44  ? 13.15518  -5.98420  20.84155  1.000 37.16591  ? 74  MET A SD     1 
ATOM   262  C  CE     . MET A 1  44  ? 11.91631  -7.25719  20.64686  1.000 36.58894  ? 74  MET A CE     1 
ATOM   263  N  N      . ALA A 1  45  ? 13.85137  -8.24862  25.91567  1.000 25.00507  ? 75  ALA A N      1 
ATOM   264  C  CA     . ALA A 1  45  ? 13.36634  -9.12341  26.98612  1.000 24.69509  ? 75  ALA A CA     1 
ATOM   265  C  C      . ALA A 1  45  ? 12.30625  -8.41468  27.81845  1.000 21.99676  ? 75  ALA A C      1 
ATOM   266  O  O      . ALA A 1  45  ? 11.32442  -9.02706  28.25107  1.000 23.71662  ? 75  ALA A O      1 
ATOM   267  C  CB     . ALA A 1  45  ? 14.53234  -9.59419  27.85691  1.000 23.26645  ? 75  ALA A CB     1 
ATOM   268  N  N      . ILE A 1  46  ? 12.48448  -7.10970  28.05535  1.000 22.54661  ? 76  ILE A N      1 
ATOM   269  C  CA     . ILE A 1  46  ? 11.47862  -6.36110  28.80381  1.000 21.02162  ? 76  ILE A CA     1 
ATOM   270  C  C      . ILE A 1  46  ? 10.17894  -6.25293  28.00261  1.000 22.43699  ? 76  ILE A C      1 
ATOM   271  O  O      . ILE A 1  46  ? 9.07686   -6.42214  28.54587  1.000 19.91540  ? 76  ILE A O      1 
ATOM   272  C  CB     . ILE A 1  46  ? 12.04541  -4.97344  29.18726  1.000 21.07681  ? 76  ILE A CB     1 
ATOM   273  C  CG1    . ILE A 1  46  ? 13.17660  -5.14475  30.23091  1.000 20.15387  ? 76  ILE A CG1    1 
ATOM   274  C  CG2    . ILE A 1  46  ? 10.94729  -4.09253  29.73854  1.000 22.58585  ? 76  ILE A CG2    1 
ATOM   275  C  CD1    . ILE A 1  46  ? 14.04880  -3.88556  30.42727  1.000 21.85375  ? 76  ILE A CD1    1 
ATOM   276  N  N      . ARG A 1  47  ? 10.28996  -5.94549  26.70274  1.000 23.86596  ? 77  ARG A N      1 
ATOM   277  C  CA     . ARG A 1  47  ? 9.11380   -5.82938  25.84578  1.000 25.17493  ? 77  ARG A CA     1 
ATOM   278  C  C      . ARG A 1  47  ? 8.32306   -7.12882  25.82197  1.000 27.31883  ? 77  ARG A C      1 
ATOM   279  O  O      . ARG A 1  47  ? 7.09806   -7.10759  25.67528  1.000 28.16731  ? 77  ARG A O      1 
ATOM   280  C  CB     . ARG A 1  47  ? 9.52439   -5.44874  24.42273  1.000 24.46626  ? 77  ARG A CB     1 
ATOM   281  C  CG     . ARG A 1  47  ? 9.93810   -3.99945  24.24150  1.000 25.22821  ? 77  ARG A CG     1 
ATOM   282  C  CD     . ARG A 1  47  ? 10.13552  -3.70123  22.77492  1.000 34.83553  ? 77  ARG A CD     1 
ATOM   283  N  NE     . ARG A 1  47  ? 10.63769  -2.35519  22.55260  1.000 30.37484  ? 77  ARG A NE     1 
ATOM   284  C  CZ     . ARG A 1  47  ? 11.87657  -2.07235  22.16859  1.000 33.89201  ? 77  ARG A CZ     1 
ATOM   285  N  NH1    . ARG A 1  47  ? 12.76277  -3.02943  21.91661  1.000 29.37242  ? 77  ARG A NH1    1 
ATOM   286  N  NH2    . ARG A 1  47  ? 12.23609  -0.79795  22.02738  1.000 30.93142  ? 77  ARG A NH2    1 
ATOM   287  N  N      . GLN A 1  48  ? 9.00728   -8.24920  25.97440  1.000 29.01433  ? 78  GLN A N      1 
ATOM   288  C  CA     . GLN A 1  48  ? 8.37846   -9.56345  25.98042  1.000 30.98891  ? 78  GLN A CA     1 
ATOM   289  C  C      . GLN A 1  48  ? 7.97566   -10.03238 27.37549  1.000 30.46321  ? 78  GLN A C      1 
ATOM   290  O  O      . GLN A 1  48  ? 7.32369   -11.07557 27.50204  1.000 28.05472  ? 78  GLN A O      1 
ATOM   291  C  CB     . GLN A 1  48  ? 9.32591   -10.57839 25.34113  1.000 32.89801  ? 78  GLN A CB     1 
ATOM   292  C  CG     . GLN A 1  48  ? 9.56355   -10.34316 23.84081  1.000 40.83624  ? 78  GLN A CG     1 
ATOM   293  C  CD     . GLN A 1  48  ? 10.91645  -10.86110 23.36630  1.000 43.29408  ? 78  GLN A CD     1 
ATOM   294  O  OE1    . GLN A 1  48  ? 11.61619  -11.56232 24.09386  1.000 44.11153  ? 78  GLN A OE1    1 
ATOM   295  N  NE2    . GLN A 1  48  ? 11.28584  -10.51707 22.14050  1.000 41.13451  ? 78  GLN A NE2    1 
ATOM   296  N  N      . THR A 1  49  ? 8.32708   -9.29685  28.43208  1.000 29.68568  ? 79  THR A N      1 
ATOM   297  C  CA     . THR A 1  49  ? 7.93038   -9.74677  29.75621  1.000 25.21652  ? 79  THR A CA     1 
ATOM   298  C  C      . THR A 1  49  ? 7.16162   -8.63589  30.47072  1.000 28.37146  ? 79  THR A C      1 
ATOM   299  O  O      . THR A 1  49  ? 6.02424   -8.32976  30.08488  1.000 23.63736  ? 79  THR A O      1 
ATOM   300  C  CB     . THR A 1  49  ? 9.15151   -10.23142 30.54616  1.000 23.58802  ? 79  THR A CB     1 
ATOM   301  O  OG1    . THR A 1  49  ? 10.12077  -9.18446  30.63688  1.000 21.82045  ? 79  THR A OG1    1 
ATOM   302  C  CG2    . THR A 1  49  ? 9.80135   -11.42179 29.82728  1.000 26.88620  ? 79  THR A CG2    1 
ATOM   303  N  N      . TRP A 1  50  ? 7.75014   -8.02892  31.50921  1.000 18.60510  ? 80  TRP A N      1 
ATOM   304  C  CA     . TRP A 1  50  ? 7.00013   -7.10290  32.34831  1.000 20.39585  ? 80  TRP A CA     1 
ATOM   305  C  C      . TRP A 1  50  ? 6.73619   -5.76597  31.67012  1.000 22.30288  ? 80  TRP A C      1 
ATOM   306  O  O      . TRP A 1  50  ? 5.87853   -5.01962  32.14991  1.000 24.02256  ? 80  TRP A O      1 
ATOM   307  C  CB     . TRP A 1  50  ? 7.69546   -6.87735  33.71046  1.000 22.20996  ? 80  TRP A CB     1 
ATOM   308  C  CG     . TRP A 1  50  ? 9.17442   -6.50280  33.70834  1.000 23.40599  ? 80  TRP A CG     1 
ATOM   309  C  CD1    . TRP A 1  50  ? 10.23763  -7.34023  33.94196  1.000 22.55438  ? 80  TRP A CD1    1 
ATOM   310  C  CD2    . TRP A 1  50  ? 9.73506   -5.19484  33.51367  1.000 21.08593  ? 80  TRP A CD2    1 
ATOM   311  N  NE1    . TRP A 1  50  ? 11.42052  -6.63867  33.88487  1.000 19.28256  ? 80  TRP A NE1    1 
ATOM   312  C  CE2    . TRP A 1  50  ? 11.14114  -5.32087  33.61552  1.000 20.56889  ? 80  TRP A CE2    1 
ATOM   313  C  CE3    . TRP A 1  50  ? 9.18792   -3.93648  33.23027  1.000 19.63344  ? 80  TRP A CE3    1 
ATOM   314  C  CZ2    . TRP A 1  50  ? 12.00227  -4.23053  33.46241  1.000 17.43399  ? 80  TRP A CZ2    1 
ATOM   315  C  CZ3    . TRP A 1  50  ? 10.04146  -2.84430  33.07738  1.000 19.99551  ? 80  TRP A CZ3    1 
ATOM   316  C  CH2    . TRP A 1  50  ? 11.44005  -2.99246  33.19687  1.000 20.75523  ? 80  TRP A CH2    1 
ATOM   317  N  N      . GLY A 1  51  ? 7.42157   -5.46369  30.56656  1.000 22.98191  ? 81  GLY A N      1 
ATOM   318  C  CA     . GLY A 1  51  ? 7.16888   -4.23572  29.83808  1.000 23.33427  ? 81  GLY A CA     1 
ATOM   319  C  C      . GLY A 1  51  ? 6.00874   -4.30256  28.85991  1.000 27.31952  ? 81  GLY A C      1 
ATOM   320  O  O      . GLY A 1  51  ? 5.62905   -3.26804  28.30250  1.000 24.71578  ? 81  GLY A O      1 
ATOM   321  N  N      . LYS A 1  52  ? 5.41685   -5.48259  28.67712  1.000 25.18121  ? 82  LYS A N      1 
ATOM   322  C  CA     . LYS A 1  52  ? 4.35146   -5.65575  27.69548  1.000 30.10665  ? 82  LYS A CA     1 
ATOM   323  C  C      . LYS A 1  52  ? 3.11216   -4.86447  28.10581  1.000 32.37759  ? 82  LYS A C      1 
ATOM   324  O  O      . LYS A 1  52  ? 2.58755   -5.03173  29.21067  1.000 31.87467  ? 82  LYS A O      1 
ATOM   325  C  CB     . LYS A 1  52  ? 4.01368   -7.13661  27.52374  1.000 29.27133  ? 82  LYS A CB     1 
ATOM   326  C  CG     . LYS A 1  52  ? 2.98292   -7.38232  26.41313  1.000 34.47528  ? 82  LYS A CG     1 
ATOM   327  C  CD     . LYS A 1  52  ? 2.88286   -8.86966  26.05440  1.000 35.26816  ? 82  LYS A CD     1 
ATOM   328  C  CE     . LYS A 1  52  ? 4.23312   -9.44419  25.63812  1.000 46.22590  ? 82  LYS A CE     1 
ATOM   329  N  NZ     . LYS A 1  52  ? 4.52953   -9.26868  24.19051  1.000 55.12814  ? 82  LYS A NZ     1 
ATOM   330  N  N      . GLU A 1  53  ? 2.65274   -3.98532  27.22525  1.000 33.15932  ? 83  GLU A N      1 
ATOM   331  C  CA     . GLU A 1  53  ? 1.54330   -3.12182  27.58581  1.000 31.67061  ? 83  GLU A CA     1 
ATOM   332  C  C      . GLU A 1  53  ? 0.24952   -3.91559  27.68356  1.000 34.64513  ? 83  GLU A C      1 
ATOM   333  O  O      . GLU A 1  53  ? -0.00113  -4.82038  26.88480  1.000 31.06035  ? 83  GLU A O      1 
ATOM   334  C  CB     . GLU A 1  53  ? 1.43131   -1.98114  26.58528  1.000 33.51699  ? 83  GLU A CB     1 
ATOM   335  C  CG     . GLU A 1  53  ? 2.67272   -1.10299  26.64272  1.000 35.61288  ? 83  GLU A CG     1 
ATOM   336  C  CD     . GLU A 1  53  ? 2.49840   0.19629   25.90404  1.000 39.69818  ? 83  GLU A CD     1 
ATOM   337  O  OE1    . GLU A 1  53  ? 1.54461   0.29424   25.09264  1.000 37.67203  ? 83  GLU A OE1    1 
ATOM   338  O  OE2    . GLU A 1  53  ? 3.29735   1.12843   26.16274  1.000 32.54000  ? 83  GLU A OE2    1 
ATOM   339  N  N      . ARG A 1  54  ? -0.57157  -3.57445  28.67919  1.000 30.59678  ? 84  ARG A N      1 
ATOM   340  C  CA     . ARG A 1  54  ? -1.77402  -4.35224  28.94535  1.000 37.06422  ? 84  ARG A CA     1 
ATOM   341  C  C      . ARG A 1  54  ? -2.59129  -3.63614  30.00501  1.000 39.33324  ? 84  ARG A C      1 
ATOM   342  O  O      . ARG A 1  54  ? -2.13045  -2.68614  30.65433  1.000 36.66697  ? 84  ARG A O      1 
ATOM   343  C  CB     . ARG A 1  54  ? -1.43966  -5.77022  29.42231  1.000 37.95105  ? 84  ARG A CB     1 
ATOM   344  C  CG     . ARG A 1  54  ? -0.49281  -5.78839  30.62821  1.000 37.66012  ? 84  ARG A CG     1 
ATOM   345  C  CD     . ARG A 1  54  ? -0.32078  -7.20000  31.20678  1.000 40.75674  ? 84  ARG A CD     1 
ATOM   346  N  NE     . ARG A 1  54  ? 0.66106   -7.23291  32.28829  1.000 37.80147  ? 84  ARG A NE     1 
ATOM   347  C  CZ     . ARG A 1  54  ? 0.39889   -7.59510  33.53786  1.000 45.23027  ? 84  ARG A CZ     1 
ATOM   348  N  NH1    . ARG A 1  54  ? -0.79761  -8.03018  33.89492  1.000 45.56898  ? 84  ARG A NH1    1 
ATOM   349  N  NH2    . ARG A 1  54  ? 1.36675   -7.53132  34.44972  1.000 43.18347  ? 84  ARG A NH2    1 
ATOM   350  N  N      . MET A 1  55  ? -3.81328  -4.12905  30.18279  1.000 36.00429  ? 85  MET A N      1 
ATOM   351  C  CA     . MET A 1  55  ? -4.64741  -3.74449  31.30427  1.000 43.50184  ? 85  MET A CA     1 
ATOM   352  C  C      . MET A 1  55  ? -4.32603  -4.67424  32.46856  1.000 39.51868  ? 85  MET A C      1 
ATOM   353  O  O      . MET A 1  55  ? -4.32953  -5.89781  32.31334  1.000 40.49760  ? 85  MET A O      1 
ATOM   354  C  CB     . MET A 1  55  ? -6.12928  -3.82836  30.93157  1.000 38.49119  ? 85  MET A CB     1 
ATOM   355  C  CG     . MET A 1  55  ? -6.57122  -2.77917  29.91191  1.000 38.72042  ? 85  MET A CG     1 
ATOM   356  S  SD     . MET A 1  55  ? -6.57712  -1.10659  30.57421  1.000 55.22526  ? 85  MET A SD     1 
ATOM   357  C  CE     . MET A 1  55  ? -7.24476  -0.16529  29.19580  1.000 45.57786  ? 85  MET A CE     1 
ATOM   358  N  N      . VAL A 1  56  ? -4.04552  -4.08607  33.62464  1.000 34.96050  ? 86  VAL A N      1 
ATOM   359  C  CA     . VAL A 1  56  ? -3.72338  -4.79561  34.85617  1.000 43.78079  ? 86  VAL A CA     1 
ATOM   360  C  C      . VAL A 1  56  ? -4.81031  -4.40621  35.84083  1.000 48.07837  ? 86  VAL A C      1 
ATOM   361  O  O      . VAL A 1  56  ? -4.83489  -3.27065  36.33263  1.000 44.66034  ? 86  VAL A O      1 
ATOM   362  C  CB     . VAL A 1  56  ? -2.32419  -4.44208  35.38755  1.000 42.17408  ? 86  VAL A CB     1 
ATOM   363  C  CG1    . VAL A 1  56  ? -1.97224  -5.26799  36.63107  1.000 37.58882  ? 86  VAL A CG1    1 
ATOM   364  C  CG2    . VAL A 1  56  ? -1.28620  -4.65341  34.29355  1.000 40.01484  ? 86  VAL A CG2    1 
ATOM   365  N  N      . LYS A 1  57  ? -5.73140  -5.33249  36.10096  1.000 51.90705  ? 87  LYS A N      1 
ATOM   366  C  CA     . LYS A 1  57  ? -6.88240  -5.05688  36.95549  1.000 55.13345  ? 87  LYS A CA     1 
ATOM   367  C  C      . LYS A 1  57  ? -7.66951  -3.86316  36.42313  1.000 43.77545  ? 87  LYS A C      1 
ATOM   368  O  O      . LYS A 1  57  ? -8.15639  -3.02543  37.18555  1.000 54.16376  ? 87  LYS A O      1 
ATOM   369  C  CB     . LYS A 1  57  ? -6.45400  -4.83089  38.40679  1.000 57.25366  ? 87  LYS A CB     1 
ATOM   370  C  CG     . LYS A 1  57  ? -5.69251  -6.00855  38.98768  1.000 66.99866  ? 87  LYS A CG     1 
ATOM   371  C  CD     . LYS A 1  57  ? -6.62954  -7.18311  39.23415  1.000 75.56072  ? 87  LYS A CD     1 
ATOM   372  C  CE     . LYS A 1  57  ? -5.89179  -8.36222  39.84985  1.000 86.55006  ? 87  LYS A CE     1 
ATOM   373  N  NZ     . LYS A 1  57  ? -6.81640  -9.48377  40.17836  1.000 90.45722  ? 87  LYS A NZ     1 
ATOM   374  N  N      . GLY A 1  58  ? -7.78413  -3.78630  35.09796  1.000 41.67458  ? 88  GLY A N      1 
ATOM   375  C  CA     . GLY A 1  58  ? -8.48318  -2.69796  34.45162  1.000 48.15614  ? 88  GLY A CA     1 
ATOM   376  C  C      . GLY A 1  58  ? -7.71773  -1.39873  34.37578  1.000 41.68645  ? 88  GLY A C      1 
ATOM   377  O  O      . GLY A 1  58  ? -8.30299  -0.38058  33.99370  1.000 37.75738  ? 88  GLY A O      1 
ATOM   378  N  N      . LYS A 1  59  ? -6.43090  -1.39517  34.71907  1.000 39.86726  ? 89  LYS A N      1 
ATOM   379  C  CA     . LYS A 1  59  ? -5.62703  -0.17864  34.72778  1.000 35.73318  ? 89  LYS A CA     1 
ATOM   380  C  C      . LYS A 1  59  ? -4.61025  -0.25001  33.59617  1.000 31.91656  ? 89  LYS A C      1 
ATOM   381  O  O      . LYS A 1  59  ? -3.98305  -1.28599  33.39289  1.000 32.40420  ? 89  LYS A O      1 
ATOM   382  C  CB     . LYS A 1  59  ? -4.90703  -0.03327  36.07016  1.000 30.92771  ? 89  LYS A CB     1 
ATOM   383  C  CG     . LYS A 1  59  ? -5.82455  0.10574   37.29658  1.000 34.69271  ? 89  LYS A CG     1 
ATOM   384  C  CD     . LYS A 1  59  ? -6.95298  1.10331   37.11223  1.000 39.42228  ? 89  LYS A CD     1 
ATOM   385  C  CE     . LYS A 1  59  ? -7.81485  1.15400   38.37702  1.000 43.76283  ? 89  LYS A CE     1 
ATOM   386  N  NZ     . LYS A 1  59  ? -8.46266  -0.16428  38.67337  1.000 53.91231  ? 89  LYS A NZ     1 
ATOM   387  N  N      . GLN A 1  60  ? -4.41736  0.84087   32.86406  1.000 27.91210  ? 90  GLN A N      1 
ATOM   388  C  CA     . GLN A 1  60  ? -3.53508  0.77531   31.70398  1.000 29.08400  ? 90  GLN A CA     1 
ATOM   389  C  C      . GLN A 1  60  ? -2.07166  0.89766   32.12656  1.000 30.59539  ? 90  GLN A C      1 
ATOM   390  O  O      . GLN A 1  60  ? -1.70661  1.82039   32.88017  1.000 28.79065  ? 90  GLN A O      1 
ATOM   391  C  CB     . GLN A 1  60  ? -3.84341  1.87731   30.69463  1.000 28.11311  ? 90  GLN A CB     1 
ATOM   392  C  CG     . GLN A 1  60  ? -2.91620  1.83265   29.45632  1.000 32.99702  ? 90  GLN A CG     1 
ATOM   393  C  CD     . GLN A 1  60  ? -3.22234  0.68136   28.51148  1.000 42.26229  ? 90  GLN A CD     1 
ATOM   394  O  OE1    . GLN A 1  60  ? -4.34745  0.56079   28.04413  1.000 42.30296  ? 90  GLN A OE1    1 
ATOM   395  N  NE2    . GLN A 1  60  ? -2.21897  -0.14872  28.19768  1.000 35.21515  ? 90  GLN A NE2    1 
ATOM   396  N  N      . LEU A 1  61  ? -1.23760  -0.00858  31.59499  1.000 28.75992  ? 91  LEU A N      1 
ATOM   397  C  CA     . LEU A 1  61  ? 0.21245   0.02399   31.76170  1.000 24.98918  ? 91  LEU A CA     1 
ATOM   398  C  C      . LEU A 1  61  ? 0.84394   0.44099   30.44128  1.000 25.27367  ? 91  LEU A C      1 
ATOM   399  O  O      . LEU A 1  61  ? 0.47367   -0.08211  29.38631  1.000 29.76667  ? 91  LEU A O      1 
ATOM   400  C  CB     . LEU A 1  61  ? 0.73739   -1.36153  32.16945  1.000 29.40501  ? 91  LEU A CB     1 
ATOM   401  C  CG     . LEU A 1  61  ? 2.25531   -1.51750  32.10549  1.000 32.27695  ? 91  LEU A CG     1 
ATOM   402  C  CD1    . LEU A 1  61  ? 2.80217   -0.86955  33.34606  1.000 25.96658  ? 91  LEU A CD1    1 
ATOM   403  C  CD2    . LEU A 1  61  ? 2.67667   -2.99122  32.01912  1.000 31.04770  ? 91  LEU A CD2    1 
ATOM   404  N  N      . LYS A 1  62  ? 1.75915   1.41004   30.48568  1.000 22.72503  ? 92  LYS A N      1 
ATOM   405  C  CA     . LYS A 1  62  ? 2.52823   1.82004   29.31536  1.000 23.04080  ? 92  LYS A CA     1 
ATOM   406  C  C      . LYS A 1  62  ? 4.01336   1.73384   29.64053  1.000 25.33829  ? 92  LYS A C      1 
ATOM   407  O  O      . LYS A 1  62  ? 4.41067   1.99007   30.78000  1.000 27.51344  ? 92  LYS A O      1 
ATOM   408  C  CB     . LYS A 1  62  ? 2.19966   3.26340   28.88287  1.000 28.49507  ? 92  LYS A CB     1 
ATOM   409  C  CG     . LYS A 1  62  ? 0.72148   3.53533   28.58197  1.000 33.62993  ? 92  LYS A CG     1 
ATOM   410  C  CD     . LYS A 1  62  ? 0.31056   2.93185   27.25511  1.000 28.39328  ? 92  LYS A CD     1 
ATOM   411  C  CE     . LYS A 1  62  ? 1.08418   3.54853   26.11643  1.000 34.57411  ? 92  LYS A CE     1 
ATOM   412  N  NZ     . LYS A 1  62  ? 0.86203   2.77360   24.85793  1.000 34.74659  ? 92  LYS A NZ     1 
ATOM   413  N  N      . THR A 1  63  ? 4.83294   1.40807   28.63961  1.000 23.09908  ? 93  THR A N      1 
ATOM   414  C  CA     . THR A 1  63  ? 6.26660   1.20696   28.84377  1.000 28.63480  ? 93  THR A CA     1 
ATOM   415  C  C      . THR A 1  63  ? 7.06967   1.93230   27.77683  1.000 26.42011  ? 93  THR A C      1 
ATOM   416  O  O      . THR A 1  63  ? 6.84302   1.73009   26.57972  1.000 26.40657  ? 93  THR A O      1 
ATOM   417  C  CB     . THR A 1  63  ? 6.63875   -0.29431  28.82382  1.000 28.66006  ? 93  THR A CB     1 
ATOM   418  O  OG1    . THR A 1  63  ? 5.94958   -0.98033  29.87627  1.000 29.38977  ? 93  THR A OG1    1 
ATOM   419  C  CG2    . THR A 1  63  ? 8.13337   -0.47547  29.02817  1.000 26.05491  ? 93  THR A CG2    1 
ATOM   420  N  N      . PHE A 1  64  ? 8.02148   2.76385   28.20861  1.000 22.99787  ? 94  PHE A N      1 
ATOM   421  C  CA     . PHE A 1  64  ? 8.86574   3.52459   27.30133  1.000 22.95361  ? 94  PHE A CA     1 
ATOM   422  C  C      . PHE A 1  64  ? 10.31739  3.37408   27.72655  1.000 25.83382  ? 94  PHE A C      1 
ATOM   423  O  O      . PHE A 1  64  ? 10.61290  3.17649   28.91134  1.000 23.73842  ? 94  PHE A O      1 
ATOM   424  C  CB     . PHE A 1  64  ? 8.47047   5.02964   27.28286  1.000 22.83636  ? 94  PHE A CB     1 
ATOM   425  C  CG     . PHE A 1  64  ? 6.99296   5.25572   27.12253  1.000 23.47384  ? 94  PHE A CG     1 
ATOM   426  C  CD1    . PHE A 1  64  ? 6.36729   5.01035   25.91097  1.000 30.49823  ? 94  PHE A CD1    1 
ATOM   427  C  CD2    . PHE A 1  64  ? 6.22838   5.67995   28.18692  1.000 26.55309  ? 94  PHE A CD2    1 
ATOM   428  C  CE1    . PHE A 1  64  ? 4.99965   5.20819   25.77205  1.000 22.65839  ? 94  PHE A CE1    1 
ATOM   429  C  CE2    . PHE A 1  64  ? 4.86427   5.88866   28.04939  1.000 28.10629  ? 94  PHE A CE2    1 
ATOM   430  C  CZ     . PHE A 1  64  ? 4.25661   5.65205   26.84447  1.000 24.31570  ? 94  PHE A CZ     1 
ATOM   431  N  N      . PHE A 1  65  ? 11.21514  3.48818   26.74605  1.000 20.91748  ? 95  PHE A N      1 
ATOM   432  C  CA     . PHE A 1  65  ? 12.65309  3.36273   26.94170  1.000 23.90781  ? 95  PHE A CA     1 
ATOM   433  C  C      . PHE A 1  65  ? 13.35536  4.70211   26.74349  1.000 22.91204  ? 95  PHE A C      1 
ATOM   434  O  O      . PHE A 1  65  ? 13.16091  5.36651   25.71869  1.000 23.05177  ? 95  PHE A O      1 
ATOM   435  C  CB     . PHE A 1  65  ? 13.22438  2.31916   25.99362  1.000 21.28670  ? 95  PHE A CB     1 
ATOM   436  C  CG     . PHE A 1  65  ? 12.66587  0.95856   26.23744  1.000 24.64783  ? 95  PHE A CG     1 
ATOM   437  C  CD1    . PHE A 1  65  ? 13.23907  0.12611   27.19395  1.000 23.57430  ? 95  PHE A CD1    1 
ATOM   438  C  CD2    . PHE A 1  65  ? 11.52569  0.53378   25.56969  1.000 25.39806  ? 95  PHE A CD2    1 
ATOM   439  C  CE1    . PHE A 1  65  ? 12.70224  -1.12962  27.45340  1.000 21.85665  ? 95  PHE A CE1    1 
ATOM   440  C  CE2    . PHE A 1  65  ? 10.97348  -0.72577  25.82107  1.000 25.58529  ? 95  PHE A CE2    1 
ATOM   441  C  CZ     . PHE A 1  65  ? 11.57254  -1.55978  26.77636  1.000 24.21860  ? 95  PHE A CZ     1 
ATOM   442  N  N      . LEU A 1  66  ? 14.17507  5.08618   27.72692  1.000 20.26232  ? 96  LEU A N      1 
ATOM   443  C  CA     . LEU A 1  66  ? 14.87162  6.37637   27.71725  1.000 25.08246  ? 96  LEU A CA     1 
ATOM   444  C  C      . LEU A 1  66  ? 16.24450  6.21553   27.07302  1.000 24.80279  ? 96  LEU A C      1 
ATOM   445  O  O      . LEU A 1  66  ? 17.04949  5.40285   27.52513  1.000 21.40852  ? 96  LEU A O      1 
ATOM   446  C  CB     . LEU A 1  66  ? 15.01309  6.90304   29.14582  1.000 21.17857  ? 96  LEU A CB     1 
ATOM   447  C  CG     . LEU A 1  66  ? 13.72801  6.99310   29.96869  1.000 22.62452  ? 96  LEU A CG     1 
ATOM   448  C  CD1    . LEU A 1  66  ? 14.00165  7.48241   31.39368  1.000 21.18022  ? 96  LEU A CD1    1 
ATOM   449  C  CD2    . LEU A 1  66  ? 12.73088  7.94082   29.27586  1.000 26.25029  ? 96  LEU A CD2    1 
ATOM   450  N  N      . LEU A 1  67  ? 16.52577  6.99598   26.03317  1.000 23.80672  ? 97  LEU A N      1 
ATOM   451  C  CA     . LEU A 1  67  ? 17.81409  6.91090   25.36482  1.000 23.41303  ? 97  LEU A CA     1 
ATOM   452  C  C      . LEU A 1  67  ? 18.34456  8.31290   25.11910  1.000 30.39716  ? 97  LEU A C      1 
ATOM   453  O  O      . LEU A 1  67  ? 17.57312  9.24845   24.91585  1.000 23.93164  ? 97  LEU A O      1 
ATOM   454  C  CB     . LEU A 1  67  ? 17.68643  6.17755   24.02079  1.000 23.90045  ? 97  LEU A CB     1 
ATOM   455  C  CG     . LEU A 1  67  ? 17.63508  4.64485   24.11757  1.000 30.54625  ? 97  LEU A CG     1 
ATOM   456  C  CD1    . LEU A 1  67  ? 17.17328  4.06435   22.79772  1.000 31.31127  ? 97  LEU A CD1    1 
ATOM   457  C  CD2    . LEU A 1  67  ? 19.00214  4.09249   24.47965  1.000 30.67898  ? 97  LEU A CD2    1 
ATOM   458  N  N      . GLY A 1  68  ? 19.66034  8.44992   25.14708  1.000 29.03559  ? 98  GLY A N      1 
ATOM   459  C  CA     . GLY A 1  68  ? 20.29226  9.62905   24.61595  1.000 31.33720  ? 98  GLY A CA     1 
ATOM   460  C  C      . GLY A 1  68  ? 20.85409  9.35176   23.23684  1.000 37.75318  ? 98  GLY A C      1 
ATOM   461  O  O      . GLY A 1  68  ? 20.34546  8.50617   22.48904  1.000 29.70180  ? 98  GLY A O      1 
ATOM   462  N  N      . THR A 1  69  ? 21.95638  10.01761  22.91784  1.000 36.15960  ? 99  THR A N      1 
ATOM   463  C  CA     . THR A 1  69  ? 22.61962  9.85638   21.63468  1.000 38.01964  ? 99  THR A CA     1 
ATOM   464  C  C      . THR A 1  69  ? 24.00318  9.25525   21.84240  1.000 41.51354  ? 99  THR A C      1 
ATOM   465  O  O      . THR A 1  69  ? 24.50747  9.15119   22.96776  1.000 37.74980  ? 99  THR A O      1 
ATOM   466  C  CB     . THR A 1  69  ? 22.69840  11.19629  20.88234  1.000 38.30626  ? 99  THR A CB     1 
ATOM   467  O  OG1    . THR A 1  69  ? 23.26121  12.20401  21.73347  1.000 38.62756  ? 99  THR A OG1    1 
ATOM   468  C  CG2    . THR A 1  69  ? 21.31913  11.63245  20.42884  1.000 36.78407  ? 99  THR A CG2    1 
ATOM   469  N  N      . THR A 1  70  ? 24.59484  8.80538   20.73753  1.000 40.31234  ? 100 THR A N      1 
ATOM   470  C  CA     . THR A 1  70  ? 25.90041  8.16647   20.75895  1.000 44.59078  ? 100 THR A CA     1 
ATOM   471  C  C      . THR A 1  70  ? 26.70497  8.62495   19.55199  1.000 51.87109  ? 100 THR A C      1 
ATOM   472  O  O      . THR A 1  70  ? 26.14919  9.08063   18.54696  1.000 40.79829  ? 100 THR A O      1 
ATOM   473  C  CB     . THR A 1  70  ? 25.77864  6.63792   20.77121  1.000 47.88416  ? 100 THR A CB     1 
ATOM   474  O  OG1    . THR A 1  70  ? 27.08215  6.05486   20.68900  1.000 53.15880  ? 100 THR A OG1    1 
ATOM   475  C  CG2    . THR A 1  70  ? 24.92588  6.16430   19.60696  1.000 48.28439  ? 100 THR A CG2    1 
ATOM   476  N  N      . SER A 1  71  ? 28.03182  8.51406   19.67124  1.000 52.48612  ? 101 SER A N      1 
ATOM   477  C  CA     . SER A 1  71  ? 28.90043  8.83879   18.54522  1.000 57.59274  ? 101 SER A CA     1 
ATOM   478  C  C      . SER A 1  71  ? 28.80825  7.78524   17.44501  1.000 62.24701  ? 101 SER A C      1 
ATOM   479  O  O      . SER A 1  71  ? 28.92099  8.11841   16.25755  1.000 67.09499  ? 101 SER A O      1 
ATOM   480  C  CB     . SER A 1  71  ? 30.34749  8.98078   19.02401  1.000 56.89501  ? 101 SER A CB     1 
ATOM   481  O  OG     . SER A 1  71  ? 30.92491  7.71573   19.31243  1.000 65.04467  ? 101 SER A OG     1 
ATOM   482  N  N      . SER A 1  72  ? 28.57660  6.52646   17.81561  1.000 54.82885  ? 102 SER A N      1 
ATOM   483  C  CA     . SER A 1  72  ? 28.51040  5.43896   16.84753  1.000 52.36696  ? 102 SER A CA     1 
ATOM   484  C  C      . SER A 1  72  ? 27.36313  5.64488   15.86524  1.000 54.48200  ? 102 SER A C      1 
ATOM   485  O  O      . SER A 1  72  ? 26.19402  5.71255   16.26094  1.000 52.33573  ? 102 SER A O      1 
ATOM   486  C  CB     . SER A 1  72  ? 28.34377  4.11103   17.58408  1.000 55.41508  ? 102 SER A CB     1 
ATOM   487  O  OG     . SER A 1  72  ? 27.95559  3.07291   16.70002  1.000 56.33771  ? 102 SER A OG     1 
ATOM   488  N  N      . ALA A 1  73  ? 27.69944  5.73248   14.57557  1.000 57.51273  ? 103 ALA A N      1 
ATOM   489  C  CA     . ALA A 1  73  ? 26.66800  5.84257   13.55038  1.000 55.30593  ? 103 ALA A CA     1 
ATOM   490  C  C      . ALA A 1  73  ? 25.85716  4.55754   13.43819  1.000 52.15896  ? 103 ALA A C      1 
ATOM   491  O  O      . ALA A 1  73  ? 24.64823  4.60168   13.16556  1.000 55.58925  ? 103 ALA A O      1 
ATOM   492  C  CB     . ALA A 1  73  ? 27.30315  6.19843   12.20885  1.000 52.94869  ? 103 ALA A CB     1 
ATOM   493  N  N      . ALA A 1  74  ? 26.50298  3.40998   13.65437  1.000 54.89424  ? 104 ALA A N      1 
ATOM   494  C  CA     . ALA A 1  74  ? 25.79800  2.13319   13.60954  1.000 60.01731  ? 104 ALA A CA     1 
ATOM   495  C  C      . ALA A 1  74  ? 24.72783  2.05810   14.69193  1.000 55.98712  ? 104 ALA A C      1 
ATOM   496  O  O      . ALA A 1  74  ? 23.58004  1.68079   14.42398  1.000 55.50630  ? 104 ALA A O      1 
ATOM   497  C  CB     . ALA A 1  74  ? 26.79544  0.98410   13.75381  1.000 52.02235  ? 104 ALA A CB     1 
ATOM   498  N  N      . GLU A 1  75  ? 25.09303  2.40157   15.92951  1.000 59.10432  ? 105 GLU A N      1 
ATOM   499  C  CA     . GLU A 1  75  ? 24.12423  2.36913   17.01901  1.000 56.03818  ? 105 GLU A CA     1 
ATOM   500  C  C      . GLU A 1  75  ? 23.00892  3.37995   16.78174  1.000 48.43762  ? 105 GLU A C      1 
ATOM   501  O  O      . GLU A 1  75  ? 21.83423  3.10466   17.06377  1.000 49.17008  ? 105 GLU A O      1 
ATOM   502  C  CB     . GLU A 1  75  ? 24.83251  2.63637   18.34610  1.000 52.80102  ? 105 GLU A CB     1 
ATOM   503  C  CG     . GLU A 1  75  ? 25.78468  1.52131   18.77085  1.000 53.25441  ? 105 GLU A CG     1 
ATOM   504  C  CD     . GLU A 1  75  ? 26.50311  1.82794   20.07187  1.000 55.95041  ? 105 GLU A CD     1 
ATOM   505  O  OE1    . GLU A 1  75  ? 26.30474  2.93136   20.62417  1.000 61.12936  ? 105 GLU A OE1    1 
ATOM   506  O  OE2    . GLU A 1  75  ? 27.27153  0.96304   20.54869  1.000 66.35054  ? 105 GLU A OE2    1 
ATOM   507  N  N      . THR A 1  76  ? 23.35849  4.55833   16.26172  1.000 49.50123  ? 106 THR A N      1 
ATOM   508  C  CA     . THR A 1  76  ? 22.34095  5.54451   15.92278  1.000 44.91821  ? 106 THR A CA     1 
ATOM   509  C  C      . THR A 1  76  ? 21.32611  4.96204   14.94957  1.000 45.54315  ? 106 THR A C      1 
ATOM   510  O  O      . THR A 1  76  ? 20.11000  5.10441   15.13618  1.000 44.65173  ? 106 THR A O      1 
ATOM   511  C  CB     . THR A 1  76  ? 22.99561  6.79094   15.32317  1.000 48.36462  ? 106 THR A CB     1 
ATOM   512  O  OG1    . THR A 1  76  ? 23.97441  7.31510   16.23356  1.000 47.55220  ? 106 THR A OG1    1 
ATOM   513  C  CG2    . THR A 1  76  ? 21.93767  7.84654   15.04474  1.000 41.90581  ? 106 THR A CG2    1 
ATOM   514  N  N      . LYS A 1  77  ? 21.81141  4.29345   13.90001  1.000 49.35534  ? 107 LYS A N      1 
ATOM   515  C  CA     . LYS A 1  77  ? 20.90432  3.72035   12.90919  1.000 51.12502  ? 107 LYS A CA     1 
ATOM   516  C  C      . LYS A 1  77  ? 20.05638  2.60887   13.51610  1.000 50.18278  ? 107 LYS A C      1 
ATOM   517  O  O      . LYS A 1  77  ? 18.85180  2.50755   13.23825  1.000 48.55702  ? 107 LYS A O      1 
ATOM   518  C  CB     . LYS A 1  77  ? 21.69726  3.20318   11.70960  1.000 57.52145  ? 107 LYS A CB     1 
ATOM   519  C  CG     . LYS A 1  77  ? 20.83693  2.56343   10.62436  1.000 66.81763  ? 107 LYS A CG     1 
ATOM   520  C  CD     . LYS A 1  77  ? 19.74234  3.51456   10.14187  1.000 75.47892  ? 107 LYS A CD     1 
ATOM   521  C  CE     . LYS A 1  77  ? 19.03127  2.96567   8.90548   1.000 84.85776  ? 107 LYS A CE     1 
ATOM   522  N  NZ     . LYS A 1  77  ? 17.92107  3.85025   8.44162   1.000 83.24560  ? 107 LYS A NZ     1 
ATOM   523  N  N      . GLU A 1  78  ? 20.68065  1.74863   14.32261  1.000 51.88323  ? 108 GLU A N      1 
ATOM   524  C  CA     . GLU A 1  78  ? 19.94602  0.68472   14.99612  1.000 48.74247  ? 108 GLU A CA     1 
ATOM   525  C  C      . GLU A 1  78  ? 18.79137  1.25361   15.80330  1.000 43.34435  ? 108 GLU A C      1 
ATOM   526  O  O      . GLU A 1  78  ? 17.66086  0.76371   15.71873  1.000 42.81271  ? 108 GLU A O      1 
ATOM   527  C  CB     . GLU A 1  78  ? 20.88474  -0.09716  15.91279  1.000 48.71473  ? 108 GLU A CB     1 
ATOM   528  C  CG     . GLU A 1  78  ? 21.95537  -0.89868  15.19994  1.000 55.25338  ? 108 GLU A CG     1 
ATOM   529  C  CD     . GLU A 1  78  ? 23.11043  -1.27485  16.11796  1.000 68.66312  ? 108 GLU A CD     1 
ATOM   530  O  OE1    . GLU A 1  78  ? 22.98707  -1.11082  17.35365  1.000 69.36761  ? 108 GLU A OE1    1 
ATOM   531  O  OE2    . GLU A 1  78  ? 24.15317  -1.72733  15.60065  1.000 76.62316  ? 108 GLU A OE2    1 
ATOM   532  N  N      . VAL A 1  79  ? 19.06584  2.29449   16.59771  1.000 45.22692  ? 109 VAL A N      1 
ATOM   533  C  CA     . VAL A 1  79  ? 18.04686  2.86392   17.47335  1.000 41.26722  ? 109 VAL A CA     1 
ATOM   534  C  C      . VAL A 1  79  ? 16.97361  3.57768   16.66144  1.000 45.08962  ? 109 VAL A C      1 
ATOM   535  O  O      . VAL A 1  79  ? 15.78740  3.52859   17.00395  1.000 38.18785  ? 109 VAL A O      1 
ATOM   536  C  CB     . VAL A 1  79  ? 18.70055  3.78888   18.51958  1.000 35.53427  ? 109 VAL A CB     1 
ATOM   537  C  CG1    . VAL A 1  79  ? 17.69647  4.77033   19.07540  1.000 42.08510  ? 109 VAL A CG1    1 
ATOM   538  C  CG2    . VAL A 1  79  ? 19.27161  2.95009   19.64663  1.000 38.93639  ? 109 VAL A CG2    1 
ATOM   539  N  N      . ASP A 1  80  ? 17.35926  4.23546   15.56376  1.000 44.46939  ? 110 ASP A N      1 
ATOM   540  C  CA     . ASP A 1  80  ? 16.35382  4.82208   14.68426  1.000 42.88206  ? 110 ASP A CA     1 
ATOM   541  C  C      . ASP A 1  80  ? 15.39240  3.75276   14.18320  1.000 43.24047  ? 110 ASP A C      1 
ATOM   542  O  O      . ASP A 1  80  ? 14.16488  3.91867   14.23685  1.000 47.79635  ? 110 ASP A O      1 
ATOM   543  C  CB     . ASP A 1  80  ? 17.03244  5.53796   13.51968  1.000 43.80417  ? 110 ASP A CB     1 
ATOM   544  C  CG     . ASP A 1  80  ? 17.89482  6.69817   13.97698  1.000 54.50133  ? 110 ASP A CG     1 
ATOM   545  O  OD1    . ASP A 1  80  ? 17.67521  7.20375   15.10313  1.000 48.39527  ? 110 ASP A OD1    1 
ATOM   546  O  OD2    . ASP A 1  80  ? 18.78715  7.11530   13.20790  1.000 66.18507  ? 110 ASP A OD2    1 
ATOM   547  N  N      . GLN A 1  81  ? 15.94340  2.63016   13.71561  1.000 45.56703  ? 111 GLN A N      1 
ATOM   548  C  CA     . GLN A 1  81  ? 15.11532  1.53530   13.22126  1.000 49.22569  ? 111 GLN A CA     1 
ATOM   549  C  C      . GLN A 1  81  ? 14.25487  0.95034   14.33635  1.000 48.54560  ? 111 GLN A C      1 
ATOM   550  O  O      . GLN A 1  81  ? 13.07457  0.63616   14.12936  1.000 37.34905  ? 111 GLN A O      1 
ATOM   551  C  CB     . GLN A 1  81  ? 16.02287  0.45916   12.62774  1.000 53.62924  ? 111 GLN A CB     1 
ATOM   552  C  CG     . GLN A 1  81  ? 16.83079  0.94585   11.43157  1.000 62.81009  ? 111 GLN A CG     1 
ATOM   553  C  CD     . GLN A 1  81  ? 17.89207  -0.04524  10.98026  1.000 70.39271  ? 111 GLN A CD     1 
ATOM   554  O  OE1    . GLN A 1  81  ? 18.63011  0.21417   10.02664  1.000 72.36378  ? 111 GLN A OE1    1 
ATOM   555  N  NE2    . GLN A 1  81  ? 17.98375  -1.18033  11.67197  1.000 70.84501  ? 111 GLN A NE2    1 
ATOM   556  N  N      . GLU A 1  82  ? 14.83160  0.81509   15.53492  1.000 44.05832  ? 112 GLU A N      1 
ATOM   557  C  CA     . GLU A 1  82  ? 14.09057  0.28511   16.67219  1.000 37.81051  ? 112 GLU A CA     1 
ATOM   558  C  C      . GLU A 1  82  ? 12.92026  1.18386   17.04028  1.000 39.36486  ? 112 GLU A C      1 
ATOM   559  O  O      . GLU A 1  82  ? 11.81503  0.69383   17.29088  1.000 37.30412  ? 112 GLU A O      1 
ATOM   560  C  CB     . GLU A 1  82  ? 15.02879  0.10880   17.86626  1.000 40.45320  ? 112 GLU A CB     1 
ATOM   561  C  CG     . GLU A 1  82  ? 14.34823  -0.46250  19.09286  1.000 36.39438  ? 112 GLU A CG     1 
ATOM   562  C  CD     . GLU A 1  82  ? 15.27263  -0.55125  20.30326  1.000 36.01425  ? 112 GLU A CD     1 
ATOM   563  O  OE1    . GLU A 1  82  ? 16.49002  -0.31288  20.16033  1.000 36.50456  ? 112 GLU A OE1    1 
ATOM   564  O  OE2    . GLU A 1  82  ? 14.76883  -0.85817  21.40787  1.000 34.65094  ? 112 GLU A OE2    1 
ATOM   565  N  N      . SER A 1  83  ? 13.14270  2.50395   17.07370  1.000 36.53097  ? 113 SER A N      1 
ATOM   566  C  CA     . SER A 1  83  ? 12.06030  3.44269   17.35655  1.000 32.88516  ? 113 SER A CA     1 
ATOM   567  C  C      . SER A 1  83  ? 10.97993  3.36526   16.29013  1.000 39.33383  ? 113 SER A C      1 
ATOM   568  O  O      . SER A 1  83  ? 9.78196   3.45111   16.59259  1.000 33.78162  ? 113 SER A O      1 
ATOM   569  C  CB     . SER A 1  83  ? 12.61084  4.86728   17.45868  1.000 37.96909  ? 113 SER A CB     1 
ATOM   570  O  OG     . SER A 1  83  ? 11.56354  5.79970   17.67303  1.000 36.75805  ? 113 SER A OG     1 
ATOM   571  N  N      . GLN A 1  84  ? 11.38509  3.20987   15.03045  1.000 47.65542  ? 114 GLN A N      1 
ATOM   572  C  CA     . GLN A 1  84  ? 10.39694  3.08486   13.96156  1.000 47.40093  ? 114 GLN A CA     1 
ATOM   573  C  C      . GLN A 1  84  ? 9.57959   1.80888   14.12675  1.000 43.61567  ? 114 GLN A C      1 
ATOM   574  O  O      . GLN A 1  84  ? 8.35947   1.80827   13.93211  1.000 46.51140  ? 114 GLN A O      1 
ATOM   575  C  CB     . GLN A 1  84  ? 11.11497  3.10475   12.61580  1.000 51.38413  ? 114 GLN A CB     1 
ATOM   576  C  CG     . GLN A 1  84  ? 11.59631  4.49552   12.21055  1.000 56.37972  ? 114 GLN A CG     1 
ATOM   577  C  CD     . GLN A 1  84  ? 12.70090  4.44826   11.16867  1.000 62.58116  ? 114 GLN A CD     1 
ATOM   578  O  OE1    . GLN A 1  84  ? 12.93266  3.41484   10.53365  1.000 68.18693  ? 114 GLN A OE1    1 
ATOM   579  N  NE2    . GLN A 1  84  ? 13.40986  5.56221   11.00961  1.000 60.54909  ? 114 GLN A NE2    1 
ATOM   580  N  N      . ARG A 1  85  ? 10.23087  0.72656   14.53986  1.000 40.61879  ? 115 ARG A N      1 
ATOM   581  C  CA     . ARG A 1  85  ? 9.56086   -0.56221  14.65776  1.000 42.99495  ? 115 ARG A CA     1 
ATOM   582  C  C      . ARG A 1  85  ? 8.65758   -0.63105  15.88822  1.000 48.01569  ? 115 ARG A C      1 
ATOM   583  O  O      . ARG A 1  85  ? 7.56257   -1.20415  15.81538  1.000 39.22645  ? 115 ARG A O      1 
ATOM   584  C  CB     . ARG A 1  85  ? 10.62425  -1.65969  14.66774  1.000 40.94095  ? 115 ARG A CB     1 
ATOM   585  C  CG     . ARG A 1  85  ? 10.13789  -3.08256  14.71236  1.000 47.53129  ? 115 ARG A CG     1 
ATOM   586  C  CD     . ARG A 1  85  ? 11.36124  -3.99887  14.81005  1.000 57.46209  ? 115 ARG A CD     1 
ATOM   587  N  NE     . ARG A 1  85  ? 12.48168  -3.45692  14.03905  1.000 59.05316  ? 115 ARG A NE     1 
ATOM   588  C  CZ     . ARG A 1  85  ? 13.66851  -3.11394  14.53478  1.000 67.14248  ? 115 ARG A CZ     1 
ATOM   589  N  NH1    . ARG A 1  85  ? 13.96463  -3.27618  15.81689  1.000 55.83965  ? 115 ARG A NH1    1 
ATOM   590  N  NH2    . ARG A 1  85  ? 14.58504  -2.59304  13.72172  1.000 67.18098  ? 115 ARG A NH2    1 
ATOM   591  N  N      . HIS A 1  86  ? 9.07792   -0.02845  17.01442  1.000 39.12047  ? 116 HIS A N      1 
ATOM   592  C  CA     . HIS A 1  86  ? 8.38712   -0.17723  18.29146  1.000 34.62723  ? 116 HIS A CA     1 
ATOM   593  C  C      . HIS A 1  86  ? 7.68689   1.07645   18.78377  1.000 32.72321  ? 116 HIS A C      1 
ATOM   594  O  O      . HIS A 1  86  ? 6.71461   0.96039   19.53611  1.000 32.62225  ? 116 HIS A O      1 
ATOM   595  C  CB     . HIS A 1  86  ? 9.37063   -0.65860  19.37144  1.000 33.84790  ? 116 HIS A CB     1 
ATOM   596  C  CG     . HIS A 1  86  ? 9.97877   -1.99152  19.06563  1.000 37.35095  ? 116 HIS A CG     1 
ATOM   597  N  ND1    . HIS A 1  86  ? 9.26601   -3.17013  19.14738  1.000 37.33271  ? 116 HIS A ND1    1 
ATOM   598  C  CD2    . HIS A 1  86  ? 11.22367  -2.33343  18.65677  1.000 40.63744  ? 116 HIS A CD2    1 
ATOM   599  C  CE1    . HIS A 1  86  ? 10.04665  -4.17909  18.80660  1.000 37.66036  ? 116 HIS A CE1    1 
ATOM   600  N  NE2    . HIS A 1  86  ? 11.23989  -3.69936  18.50517  1.000 39.29928  ? 116 HIS A NE2    1 
ATOM   601  N  N      . GLY A 1  87  ? 8.13966   2.26488   18.38411  1.000 33.79682  ? 117 GLY A N      1 
ATOM   602  C  CA     . GLY A 1  87  ? 7.47414   3.50735   18.77190  1.000 34.59648  ? 117 GLY A CA     1 
ATOM   603  C  C      . GLY A 1  87  ? 7.43138   3.78517   20.26444  1.000 36.04194  ? 117 GLY A C      1 
ATOM   604  O  O      . GLY A 1  87  ? 6.53904   4.50295   20.73882  1.000 31.71123  ? 117 GLY A O      1 
ATOM   605  N  N      . ASP A 1  88  ? 8.38089   3.24724   21.02903  1.000 32.53192  ? 118 ASP A N      1 
ATOM   606  C  CA     . ASP A 1  88  ? 8.30109   3.37061   22.48024  1.000 28.92990  ? 118 ASP A CA     1 
ATOM   607  C  C      . ASP A 1  88  ? 9.57632   3.95110   23.06961  1.000 30.02252  ? 118 ASP A C      1 
ATOM   608  O  O      . ASP A 1  88  ? 9.86543   3.71334   24.24584  1.000 28.40993  ? 118 ASP A O      1 
ATOM   609  C  CB     . ASP A 1  88  ? 7.95956   2.01545   23.13205  1.000 29.27644  ? 118 ASP A CB     1 
ATOM   610  C  CG     . ASP A 1  88  ? 8.91374   0.90987   22.73729  1.000 27.87604  ? 118 ASP A CG     1 
ATOM   611  O  OD1    . ASP A 1  88  ? 9.94061   1.19046   22.08929  1.000 30.39814  ? 118 ASP A OD1    1 
ATOM   612  O  OD2    . ASP A 1  88  ? 8.64399   -0.26830  23.10448  1.000 33.87476  ? 118 ASP A OD2    1 
ATOM   613  N  N      . ILE A 1  89  ? 10.33595  4.70689   22.27916  1.000 27.14676  ? 119 ILE A N      1 
ATOM   614  C  CA     . ILE A 1  89  ? 11.59057  5.30320   22.71056  1.000 25.43788  ? 119 ILE A CA     1 
ATOM   615  C  C      . ILE A 1  89  ? 11.39558  6.80282   22.91078  1.000 28.41550  ? 119 ILE A C      1 
ATOM   616  O  O      . ILE A 1  89  ? 10.80396  7.48211   22.06241  1.000 27.25467  ? 119 ILE A O      1 
ATOM   617  C  CB     . ILE A 1  89  ? 12.70933  5.01349   21.70142  1.000 23.61088  ? 119 ILE A CB     1 
ATOM   618  C  CG1    . ILE A 1  89  ? 13.03268  3.51200   21.71573  1.000 28.71959  ? 119 ILE A CG1    1 
ATOM   619  C  CG2    . ILE A 1  89  ? 13.93627  5.83402   22.01821  1.000 24.67763  ? 119 ILE A CG2    1 
ATOM   620  C  CD1    . ILE A 1  89  ? 14.12312  3.12844   20.75888  1.000 36.88733  ? 119 ILE A CD1    1 
ATOM   621  N  N      . ILE A 1  90  ? 11.85221  7.30114   24.05541  1.000 24.74266  ? 120 ILE A N      1 
ATOM   622  C  CA     . ILE A 1  90  ? 11.93425  8.72345   24.36491  1.000 25.84607  ? 120 ILE A CA     1 
ATOM   623  C  C      . ILE A 1  90  ? 13.40275  9.10402   24.24845  1.000 28.69989  ? 120 ILE A C      1 
ATOM   624  O  O      . ILE A 1  90  ? 14.25105  8.51498   24.93238  1.000 26.36776  ? 120 ILE A O      1 
ATOM   625  C  CB     . ILE A 1  90  ? 11.41778  9.02777   25.78412  1.000 25.54293  ? 120 ILE A CB     1 
ATOM   626  C  CG1    . ILE A 1  90  ? 9.95823   8.59073   25.95147  1.000 27.48008  ? 120 ILE A CG1    1 
ATOM   627  C  CG2    . ILE A 1  90  ? 11.65710  10.53386  26.15174  1.000 22.52020  ? 120 ILE A CG2    1 
ATOM   628  C  CD1    . ILE A 1  90  ? 9.51449   8.46912   27.41613  1.000 25.65089  ? 120 ILE A CD1    1 
ATOM   629  N  N      . GLN A 1  91  ? 13.71838  10.08508  23.39879  1.000 28.21409  ? 121 GLN A N      1 
ATOM   630  C  CA     . GLN A 1  91  ? 15.11479  10.40735  23.15530  1.000 24.12685  ? 121 GLN A CA     1 
ATOM   631  C  C      . GLN A 1  91  ? 15.33540  11.91083  23.11516  1.000 27.89753  ? 121 GLN A C      1 
ATOM   632  O  O      . GLN A 1  91  ? 14.51731  12.65386  22.56076  1.000 32.32728  ? 121 GLN A O      1 
ATOM   633  C  CB     . GLN A 1  91  ? 15.60869  9.80988   21.83619  1.000 27.88604  ? 121 GLN A CB     1 
ATOM   634  C  CG     . GLN A 1  91  ? 17.11445  9.98406   21.61122  1.000 26.55808  ? 121 GLN A CG     1 
ATOM   635  C  CD     . GLN A 1  91  ? 17.54506  9.46482   20.23607  1.000 34.03013  ? 121 GLN A CD     1 
ATOM   636  O  OE1    . GLN A 1  91  ? 16.92766  9.77747   19.22750  1.000 37.78535  ? 121 GLN A OE1    1 
ATOM   637  N  NE2    . GLN A 1  91  ? 18.58841  8.64517   20.20801  1.000 33.49887  ? 121 GLN A NE2    1 
ATOM   638  N  N      . LYS A 1  92  ? 16.47370  12.33746  23.66619  1.000 27.95005  ? 122 LYS A N      1 
ATOM   639  C  CA     . LYS A 1  92  ? 16.96487  13.70468  23.52306  1.000 31.10231  ? 122 LYS A CA     1 
ATOM   640  C  C      . LYS A 1  92  ? 18.45032  13.63655  23.20340  1.000 35.11567  ? 122 LYS A C      1 
ATOM   641  O  O      . LYS A 1  92  ? 19.10129  12.59383  23.36494  1.000 27.53167  ? 122 LYS A O      1 
ATOM   642  C  CB     . LYS A 1  92  ? 16.72322  14.55405  24.78320  1.000 28.34871  ? 122 LYS A CB     1 
ATOM   643  C  CG     . LYS A 1  92  ? 15.26168  14.87305  25.05180  1.000 32.57203  ? 122 LYS A CG     1 
ATOM   644  C  CD     . LYS A 1  92  ? 15.05958  15.83330  26.23125  1.000 31.43166  ? 122 LYS A CD     1 
ATOM   645  C  CE     . LYS A 1  92  ? 15.68729  17.18817  25.97549  1.000 38.27574  ? 122 LYS A CE     1 
ATOM   646  N  NZ     . LYS A 1  92  ? 15.25078  18.19528  26.99303  1.000 34.00887  ? 122 LYS A NZ     1 
ATOM   647  N  N      . ASP A 1  93  ? 18.98487  14.76356  22.72820  1.000 35.46061  ? 123 ASP A N      1 
ATOM   648  C  CA     . ASP A 1  93  ? 20.36962  14.81195  22.25123  1.000 36.71778  ? 123 ASP A CA     1 
ATOM   649  C  C      . ASP A 1  93  ? 21.32154  15.10098  23.40893  1.000 39.01003  ? 123 ASP A C      1 
ATOM   650  O  O      . ASP A 1  93  ? 21.73487  16.23720  23.65549  1.000 41.84162  ? 123 ASP A O      1 
ATOM   651  C  CB     . ASP A 1  93  ? 20.51905  15.85522  21.14862  1.000 42.12446  ? 123 ASP A CB     1 
ATOM   652  C  CG     . ASP A 1  93  ? 21.87582  15.79449  20.47813  1.000 46.53846  ? 123 ASP A CG     1 
ATOM   653  O  OD1    . ASP A 1  93  ? 22.65867  14.86752  20.79265  1.000 45.89787  ? 123 ASP A OD1    1 
ATOM   654  O  OD2    . ASP A 1  93  ? 22.16183  16.66832  19.63064  1.000 57.93831  ? 123 ASP A OD2    1 
ATOM   655  N  N      . PHE A 1  94  ? 21.70045  14.04220  24.11514  1.000 31.68156  ? 124 PHE A N      1 
ATOM   656  C  CA     . PHE A 1  94  ? 22.75136  14.12176  25.11210  1.000 35.02731  ? 124 PHE A CA     1 
ATOM   657  C  C      . PHE A 1  94  ? 23.54065  12.82778  25.01988  1.000 32.85865  ? 124 PHE A C      1 
ATOM   658  O  O      . PHE A 1  94  ? 22.96848  11.76870  24.75209  1.000 33.11718  ? 124 PHE A O      1 
ATOM   659  C  CB     . PHE A 1  94  ? 22.19829  14.34167  26.52624  1.000 31.77755  ? 124 PHE A CB     1 
ATOM   660  C  CG     . PHE A 1  94  ? 21.40157  13.18172  27.04473  1.000 28.26743  ? 124 PHE A CG     1 
ATOM   661  C  CD1    . PHE A 1  94  ? 20.04151  13.09358  26.79006  1.000 28.89373  ? 124 PHE A CD1    1 
ATOM   662  C  CD2    . PHE A 1  94  ? 22.02352  12.15758  27.74319  1.000 27.17788  ? 124 PHE A CD2    1 
ATOM   663  C  CE1    . PHE A 1  94  ? 19.30009  12.00068  27.25263  1.000 30.73512  ? 124 PHE A CE1    1 
ATOM   664  C  CE2    . PHE A 1  94  ? 21.29926  11.07699  28.20489  1.000 27.07156  ? 124 PHE A CE2    1 
ATOM   665  C  CZ     . PHE A 1  94  ? 19.93732  10.99698  27.95754  1.000 26.55596  ? 124 PHE A CZ     1 
ATOM   666  N  N      . LEU A 1  95  ? 24.85780  12.92602  25.18935  1.000 32.79015  ? 125 LEU A N      1 
ATOM   667  C  CA     . LEU A 1  95  ? 25.71264  11.75252  25.13726  1.000 35.82020  ? 125 LEU A CA     1 
ATOM   668  C  C      . LEU A 1  95  ? 25.27402  10.72840  26.18066  1.000 37.86863  ? 125 LEU A C      1 
ATOM   669  O  O      . LEU A 1  95  ? 25.33921  10.98508  27.38577  1.000 32.58519  ? 125 LEU A O      1 
ATOM   670  C  CB     . LEU A 1  95  ? 27.17232  12.14217  25.36347  1.000 38.02668  ? 125 LEU A CB     1 
ATOM   671  C  CG     . LEU A 1  95  ? 28.13152  10.95032  25.24030  1.000 39.74842  ? 125 LEU A CG     1 
ATOM   672  C  CD1    . LEU A 1  95  ? 28.04170  10.32862  23.84542  1.000 41.78544  ? 125 LEU A CD1    1 
ATOM   673  C  CD2    . LEU A 1  95  ? 29.56763  11.31883  25.57939  1.000 43.91838  ? 125 LEU A CD2    1 
ATOM   674  N  N      . ASP A 1  96  ? 24.82573  9.57318   25.71480  1.000 36.10208  ? 126 ASP A N      1 
ATOM   675  C  CA     . ASP A 1  96  ? 24.28772  8.53641   26.59095  1.000 26.96705  ? 126 ASP A CA     1 
ATOM   676  C  C      . ASP A 1  96  ? 25.43142  7.73276   27.20768  1.000 30.81879  ? 126 ASP A C      1 
ATOM   677  O  O      . ASP A 1  96  ? 25.90677  6.75529   26.63552  1.000 34.44178  ? 126 ASP A O      1 
ATOM   678  C  CB     . ASP A 1  96  ? 23.32003  7.66547   25.80230  1.000 29.93502  ? 126 ASP A CB     1 
ATOM   679  C  CG     . ASP A 1  96  ? 22.44210  6.82069   26.69522  1.000 32.24338  ? 126 ASP A CG     1 
ATOM   680  O  OD1    . ASP A 1  96  ? 22.82944  6.60614   27.86544  1.000 31.67450  ? 126 ASP A OD1    1 
ATOM   681  O  OD2    . ASP A 1  96  ? 21.36452  6.39870   26.22617  1.000 30.38892  ? 126 ASP A OD2    1 
ATOM   682  N  N      . VAL A 1  97  ? 25.88785  8.15732   28.39577  1.000 31.03982  ? 127 VAL A N      1 
ATOM   683  C  CA     . VAL A 1  97  ? 26.92817  7.45704   29.15243  1.000 31.24838  ? 127 VAL A CA     1 
ATOM   684  C  C      . VAL A 1  97  ? 26.54743  7.42912   30.62824  1.000 31.52150  ? 127 VAL A C      1 
ATOM   685  O  O      . VAL A 1  97  ? 25.68017  8.17908   31.07465  1.000 30.09445  ? 127 VAL A O      1 
ATOM   686  C  CB     . VAL A 1  97  ? 28.30913  8.12925   29.00189  1.000 35.96210  ? 127 VAL A CB     1 
ATOM   687  C  CG1    . VAL A 1  97  ? 28.79201  8.02977   27.56699  1.000 32.51460  ? 127 VAL A CG1    1 
ATOM   688  C  CG2    . VAL A 1  97  ? 28.22160  9.57530   29.45869  1.000 31.65119  ? 127 VAL A CG2    1 
ATOM   689  N  N      . TYR A 1  98  ? 27.21769  6.55785   31.40165  1.000 31.29441  ? 128 TYR A N      1 
ATOM   690  C  CA     . TYR A 1  98  ? 26.79814  6.37448   32.79118  1.000 31.43483  ? 128 TYR A CA     1 
ATOM   691  C  C      . TYR A 1  98  ? 26.74151  7.70940   33.52903  1.000 32.93596  ? 128 TYR A C      1 
ATOM   692  O  O      . TYR A 1  98  ? 25.76212  7.99541   34.23439  1.000 31.30990  ? 128 TYR A O      1 
ATOM   693  C  CB     . TYR A 1  98  ? 27.70540  5.38923   33.54834  1.000 32.68678  ? 128 TYR A CB     1 
ATOM   694  C  CG     . TYR A 1  98  ? 27.08992  4.94782   34.88148  1.000 31.63308  ? 128 TYR A CG     1 
ATOM   695  C  CD1    . TYR A 1  98  ? 27.33339  5.65626   36.05730  1.000 39.33513  ? 128 TYR A CD1    1 
ATOM   696  C  CD2    . TYR A 1  98  ? 26.24533  3.83891   34.95413  1.000 38.22328  ? 128 TYR A CD2    1 
ATOM   697  C  CE1    . TYR A 1  98  ? 26.75659  5.27196   37.27785  1.000 33.20665  ? 128 TYR A CE1    1 
ATOM   698  C  CE2    . TYR A 1  98  ? 25.66406  3.44014   36.16971  1.000 35.88375  ? 128 TYR A CE2    1 
ATOM   699  C  CZ     . TYR A 1  98  ? 25.92269  4.17205   37.32472  1.000 42.05325  ? 128 TYR A CZ     1 
ATOM   700  O  OH     . TYR A 1  98  ? 25.35502  3.79632   38.52290  1.000 39.54270  ? 128 TYR A OH     1 
ATOM   701  N  N      . TYR A 1  99  ? 27.75843  8.55885   33.35605  1.000 27.05518  ? 129 TYR A N      1 
ATOM   702  C  CA     . TYR A 1  99  ? 27.77504  9.80048   34.13349  1.000 29.98628  ? 129 TYR A CA     1 
ATOM   703  C  C      . TYR A 1  99  ? 26.87079  10.88478  33.57216  1.000 30.02288  ? 129 TYR A C      1 
ATOM   704  O  O      . TYR A 1  99  ? 26.90935  12.01845  34.07488  1.000 30.53928  ? 129 TYR A O      1 
ATOM   705  C  CB     . TYR A 1  99  ? 29.20860  10.28828  34.30354  1.000 31.96765  ? 129 TYR A CB     1 
ATOM   706  C  CG     . TYR A 1  99  ? 29.90135  9.35173   35.26166  1.000 42.92055  ? 129 TYR A CG     1 
ATOM   707  C  CD1    . TYR A 1  99  ? 29.21785  8.86976   36.37870  1.000 38.82132  ? 129 TYR A CD1    1 
ATOM   708  C  CD2    . TYR A 1  99  ? 31.18648  8.88626   35.02863  1.000 53.52987  ? 129 TYR A CD2    1 
ATOM   709  C  CE1    . TYR A 1  99  ? 29.80711  7.99049   37.25702  1.000 41.55043  ? 129 TYR A CE1    1 
ATOM   710  C  CE2    . TYR A 1  99  ? 31.78989  7.99333   35.90884  1.000 53.99506  ? 129 TYR A CE2    1 
ATOM   711  C  CZ     . TYR A 1  99  ? 31.09288  7.55044   37.02096  1.000 52.42439  ? 129 TYR A CZ     1 
ATOM   712  O  OH     . TYR A 1  99  ? 31.66654  6.65995   37.90265  1.000 51.91775  ? 129 TYR A OH     1 
ATOM   713  N  N      . ASN A 1  100 ? 26.02820  10.55032  32.59433  1.000 30.34784  ? 130 ASN A N      1 
ATOM   714  C  CA     . ASN A 1  100 ? 24.94362  11.41441  32.14396  1.000 24.01258  ? 130 ASN A CA     1 
ATOM   715  C  C      . ASN A 1  100 ? 23.56889  10.86746  32.53064  1.000 25.54054  ? 130 ASN A C      1 
ATOM   716  O  O      . ASN A 1  100 ? 22.54418  11.36955  32.05008  1.000 22.01190  ? 130 ASN A O      1 
ATOM   717  C  CB     . ASN A 1  100 ? 25.02666  11.62960  30.62552  1.000 24.96737  ? 130 ASN A CB     1 
ATOM   718  C  CG     . ASN A 1  100 ? 25.63892  12.98884  30.27808  1.000 30.88216  ? 130 ASN A CG     1 
ATOM   719  O  OD1    . ASN A 1  100 ? 25.69351  13.86134  31.13247  1.000 29.56066  ? 130 ASN A OD1    1 
ATOM   720  N  ND2    . ASN A 1  100 ? 26.09608  13.16181  29.04277  1.000 34.77270  ? 130 ASN A ND2    1 
ATOM   721  N  N      . LEU A 1  101 ? 23.52144  9.86334   33.40937  1.000 22.58000  ? 131 LEU A N      1 
ATOM   722  C  CA     . LEU A 1  101 ? 22.23157  9.30560   33.80972  1.000 19.99002  ? 131 LEU A CA     1 
ATOM   723  C  C      . LEU A 1  101 ? 21.29485  10.35141  34.41134  1.000 18.86556  ? 131 LEU A C      1 
ATOM   724  O  O      . LEU A 1  101 ? 20.07537  10.21857  34.29633  1.000 20.89513  ? 131 LEU A O      1 
ATOM   725  C  CB     . LEU A 1  101 ? 22.46576  8.15331   34.78542  1.000 20.86224  ? 131 LEU A CB     1 
ATOM   726  C  CG     . LEU A 1  101 ? 22.90200  6.90564   34.02784  1.000 21.06036  ? 131 LEU A CG     1 
ATOM   727  C  CD1    . LEU A 1  101 ? 23.19362  5.75437   35.01633  1.000 25.01822  ? 131 LEU A CD1    1 
ATOM   728  C  CD2    . LEU A 1  101 ? 21.84366  6.50636   33.00292  1.000 24.57440  ? 131 LEU A CD2    1 
ATOM   729  N  N      . THR A 1  102 ? 21.82258  11.39298  35.06315  1.000 19.26488  ? 132 THR A N      1 
ATOM   730  C  CA     . THR A 1  102 ? 20.92422  12.43197  35.57426  1.000 20.18484  ? 132 THR A CA     1 
ATOM   731  C  C      . THR A 1  102 ? 20.13473  13.10065  34.44142  1.000 21.54770  ? 132 THR A C      1 
ATOM   732  O  O      . THR A 1  102 ? 18.90187  13.24475  34.52460  1.000 20.02882  ? 132 THR A O      1 
ATOM   733  C  CB     . THR A 1  102 ? 21.70174  13.44894  36.40115  1.000 21.29988  ? 132 THR A CB     1 
ATOM   734  O  OG1    . THR A 1  102 ? 22.21249  12.79470  37.58316  1.000 17.84744  ? 132 THR A OG1    1 
ATOM   735  C  CG2    . THR A 1  102 ? 20.79762  14.63367  36.79447  1.000 18.43959  ? 132 THR A CG2    1 
ATOM   736  N  N      . LEU A 1  103 ? 20.81492  13.46527  33.34568  1.000 22.92793  ? 133 LEU A N      1 
ATOM   737  C  CA     . LEU A 1  103 ? 20.08655  13.99313  32.19229  1.000 21.73518  ? 133 LEU A CA     1 
ATOM   738  C  C      . LEU A 1  103 ? 19.03320  13.00188  31.73444  1.000 23.16619  ? 133 LEU A C      1 
ATOM   739  O  O      . LEU A 1  103 ? 17.89047  13.38162  31.42661  1.000 26.72880  ? 133 LEU A O      1 
ATOM   740  C  CB     . LEU A 1  103 ? 21.03812  14.29867  31.03960  1.000 26.14759  ? 133 LEU A CB     1 
ATOM   741  C  CG     . LEU A 1  103 ? 22.12310  15.33225  31.31969  1.000 33.39039  ? 133 LEU A CG     1 
ATOM   742  C  CD1    . LEU A 1  103 ? 22.90867  15.62743  30.05103  1.000 35.51588  ? 133 LEU A CD1    1 
ATOM   743  C  CD2    . LEU A 1  103 ? 21.45692  16.58194  31.85747  1.000 32.63083  ? 133 LEU A CD2    1 
ATOM   744  N  N      . LYS A 1  104 ? 19.40308  11.71782  31.67924  1.000 19.98729  ? 134 LYS A N      1 
ATOM   745  C  CA     . LYS A 1  104 ? 18.44662  10.73124  31.19035  1.000 18.68561  ? 134 LYS A CA     1 
ATOM   746  C  C      . LYS A 1  104 ? 17.20225  10.72600  32.05917  1.000 20.36643  ? 134 LYS A C      1 
ATOM   747  O  O      . LYS A 1  104 ? 16.07067  10.77858  31.54731  1.000 19.65712  ? 134 LYS A O      1 
ATOM   748  C  CB     . LYS A 1  104 ? 19.08064  9.34223   31.14579  1.000 18.67610  ? 134 LYS A CB     1 
ATOM   749  C  CG     . LYS A 1  104 ? 18.12507  8.31136   30.54848  1.000 20.00301  ? 134 LYS A CG     1 
ATOM   750  C  CD     . LYS A 1  104 ? 18.82040  6.97628   30.24702  1.000 19.95416  ? 134 LYS A CD     1 
ATOM   751  C  CE     . LYS A 1  104 ? 19.73788  7.09084   29.03167  1.000 26.09046  ? 134 LYS A CE     1 
ATOM   752  N  NZ     . LYS A 1  104 ? 20.05040  5.72684   28.46126  1.000 23.57335  ? 134 LYS A NZ     1 
ATOM   753  N  N      . THR A 1  105 ? 17.39711  10.67822  33.38817  1.000 21.56834  ? 135 THR A N      1 
ATOM   754  C  CA     . THR A 1  105 ? 16.25326  10.67789  34.29598  1.000 17.31333  ? 135 THR A CA     1 
ATOM   755  C  C      . THR A 1  105 ? 15.44034  11.95052  34.11506  1.000 20.30387  ? 135 THR A C      1 
ATOM   756  O  O      . THR A 1  105 ? 14.19357  11.91483  34.04286  1.000 19.31134  ? 135 THR A O      1 
ATOM   757  C  CB     . THR A 1  105 ? 16.75180  10.52267  35.74150  1.000 19.95829  ? 135 THR A CB     1 
ATOM   758  O  OG1    . THR A 1  105 ? 17.12249  9.14717   35.96008  1.000 18.76948  ? 135 THR A OG1    1 
ATOM   759  C  CG2    . THR A 1  105 ? 15.69360  10.91465  36.77775  1.000 17.28007  ? 135 THR A CG2    1 
ATOM   760  N  N      . MET A 1  106 ? 16.12412  13.08763  34.01753  1.000 19.81365  ? 136 MET A N      1 
ATOM   761  C  CA     . MET A 1  106 ? 15.35763  14.31997  33.88681  1.000 17.06656  ? 136 MET A CA     1 
ATOM   762  C  C      . MET A 1  106 ? 14.60937  14.34735  32.55985  1.000 20.75849  ? 136 MET A C      1 
ATOM   763  O  O      . MET A 1  106 ? 13.48125  14.86157  32.50214  1.000 24.51122  ? 136 MET A O      1 
ATOM   764  C  CB     . MET A 1  106 ? 16.26334  15.53378  34.08177  1.000 21.64487  ? 136 MET A CB     1 
ATOM   765  C  CG     . MET A 1  106 ? 16.64860  15.75478  35.55360  1.000 20.41881  ? 136 MET A CG     1 
ATOM   766  S  SD     . MET A 1  106 ? 15.24439  15.75357  36.68304  1.000 25.45138  ? 136 MET A SD     1 
ATOM   767  C  CE     . MET A 1  106 ? 14.16828  16.97868  35.88873  1.000 25.57982  ? 136 MET A CE     1 
ATOM   768  N  N      . MET A 1  107 ? 15.17550  13.74245  31.50931  1.000 23.31769  ? 137 MET A N      1 
ATOM   769  C  CA     . MET A 1  107 ? 14.42422  13.62001  30.25776  1.000 22.81339  ? 137 MET A CA     1 
ATOM   770  C  C      . MET A 1  107 ? 13.11397  12.87965  30.50204  1.000 27.34101  ? 137 MET A C      1 
ATOM   771  O  O      . MET A 1  107 ? 12.03399  13.33421  30.10164  1.000 23.15470  ? 137 MET A O      1 
ATOM   772  C  CB     . MET A 1  107 ? 15.27008  12.90014  29.20305  1.000 21.37382  ? 137 MET A CB     1 
ATOM   773  C  CG     . MET A 1  107 ? 14.48293  12.48907  27.93815  1.000 20.41837  ? 137 MET A CG     1 
ATOM   774  S  SD     . MET A 1  107 ? 15.47959  11.64238  26.72091  1.000 26.69854  ? 137 MET A SD     1 
ATOM   775  C  CE     . MET A 1  107 ? 15.79621  10.07313  27.57842  1.000 26.10398  ? 137 MET A CE     1 
ATOM   776  N  N      . GLY A 1  108 ? 13.19087  11.73002  31.17905  1.000 25.85309  ? 138 GLY A N      1 
ATOM   777  C  CA     . GLY A 1  108 ? 11.97680  10.98457  31.43764  1.000 23.24085  ? 138 GLY A CA     1 
ATOM   778  C  C      . GLY A 1  108 ? 10.99201  11.81569  32.21848  1.000 20.92220  ? 138 GLY A C      1 
ATOM   779  O  O      . GLY A 1  108 ? 9.80361   11.87192  31.88783  1.000 24.24594  ? 138 GLY A O      1 
ATOM   780  N  N      . ILE A 1  109 ? 11.47769  12.50801  33.24145  1.000 18.95815  ? 139 ILE A N      1 
ATOM   781  C  CA     . ILE A 1  109 ? 10.56447  13.28952  34.05549  1.000 18.37995  ? 139 ILE A CA     1 
ATOM   782  C  C      . ILE A 1  109 ? 9.96078   14.40531  33.21003  1.000 21.38725  ? 139 ILE A C      1 
ATOM   783  O  O      . ILE A 1  109 ? 8.75250   14.68803  33.28460  1.000 22.21969  ? 139 ILE A O      1 
ATOM   784  C  CB     . ILE A 1  109 ? 11.29590  13.80104  35.31149  1.000 22.30893  ? 139 ILE A CB     1 
ATOM   785  C  CG1    . ILE A 1  109 ? 11.41926  12.65678  36.33493  1.000 26.25714  ? 139 ILE A CG1    1 
ATOM   786  C  CG2    . ILE A 1  109 ? 10.63042  15.04138  35.88737  1.000 22.74594  ? 139 ILE A CG2    1 
ATOM   787  C  CD1    . ILE A 1  109 ? 12.46657  12.89306  37.44253  1.000 27.06785  ? 139 ILE A CD1    1 
ATOM   788  N  N      . GLU A 1  110 ? 10.79152  15.02615  32.36331  1.000 21.56061  ? 140 GLU A N      1 
ATOM   789  C  CA     . GLU A 1  110 ? 10.30011  16.07499  31.48024  1.000 22.90545  ? 140 GLU A CA     1 
ATOM   790  C  C      . GLU A 1  110 ? 9.21547   15.52629  30.57191  1.000 23.97955  ? 140 GLU A C      1 
ATOM   791  O  O      . GLU A 1  110 ? 8.17639   16.16892  30.36235  1.000 26.66871  ? 140 GLU A O      1 
ATOM   792  C  CB     . GLU A 1  110 ? 11.44631  16.64314  30.65471  1.000 26.13626  ? 140 GLU A CB     1 
ATOM   793  C  CG     . GLU A 1  110 ? 11.00979  17.78565  29.72567  1.000 29.15406  ? 140 GLU A CG     1 
ATOM   794  C  CD     . GLU A 1  110 ? 12.13055  18.24830  28.80290  1.000 36.19070  ? 140 GLU A CD     1 
ATOM   795  O  OE1    . GLU A 1  110 ? 13.25376  17.73088  28.92632  1.000 33.44064  ? 140 GLU A OE1    1 
ATOM   796  O  OE2    . GLU A 1  110 ? 11.88597  19.12501  27.94698  1.000 33.07622  ? 140 GLU A OE2    1 
ATOM   797  N  N      . TRP A 1  111 ? 9.43271   14.31778  30.04854  1.000 23.20286  ? 141 TRP A N      1 
ATOM   798  C  CA     . TRP A 1  111 ? 8.44420   13.73787  29.15312  1.000 21.76537  ? 141 TRP A CA     1 
ATOM   799  C  C      . TRP A 1  111 ? 7.11335   13.60522  29.87515  1.000 26.79152  ? 141 TRP A C      1 
ATOM   800  O  O      . TRP A 1  111 ? 6.07093   14.05208  29.36884  1.000 27.90069  ? 141 TRP A O      1 
ATOM   801  C  CB     . TRP A 1  111 ? 8.93437   12.39626  28.59251  1.000 22.57521  ? 141 TRP A CB     1 
ATOM   802  C  CG     . TRP A 1  111 ? 7.91289   11.81941  27.66471  1.000 26.02471  ? 141 TRP A CG     1 
ATOM   803  C  CD1    . TRP A 1  111 ? 7.76435   12.07768  26.33045  1.000 30.58043  ? 141 TRP A CD1    1 
ATOM   804  C  CD2    . TRP A 1  111 ? 6.85982   10.92030  28.02644  1.000 23.56762  ? 141 TRP A CD2    1 
ATOM   805  N  NE1    . TRP A 1  111 ? 6.68008   11.38287  25.83702  1.000 32.54111  ? 141 TRP A NE1    1 
ATOM   806  C  CE2    . TRP A 1  111 ? 6.10834   10.66438  26.85815  1.000 31.88274  ? 141 TRP A CE2    1 
ATOM   807  C  CE3    . TRP A 1  111 ? 6.49145   10.28925  29.22515  1.000 23.61667  ? 141 TRP A CE3    1 
ATOM   808  C  CZ2    . TRP A 1  111 ? 5.00016   9.81003   26.84973  1.000 33.12786  ? 141 TRP A CZ2    1 
ATOM   809  C  CZ3    . TRP A 1  111 ? 5.38008   9.44172   29.21541  1.000 32.74261  ? 141 TRP A CZ3    1 
ATOM   810  C  CH2    . TRP A 1  111 ? 4.64695   9.21631   28.02701  1.000 30.28417  ? 141 TRP A CH2    1 
ATOM   811  N  N      . VAL A 1  112 ? 7.13814   13.05696  31.09945  1.000 21.18111  ? 142 VAL A N      1 
ATOM   812  C  CA     . VAL A 1  112 ? 5.89269   12.92416  31.85048  1.000 21.57539  ? 142 VAL A CA     1 
ATOM   813  C  C      . VAL A 1  112 ? 5.24852   14.28973  32.00770  1.000 27.84712  ? 142 VAL A C      1 
ATOM   814  O  O      . VAL A 1  112 ? 4.04412   14.46779  31.77088  1.000 28.56954  ? 142 VAL A O      1 
ATOM   815  C  CB     . VAL A 1  112 ? 6.13966   12.27221  33.22052  1.000 25.53924  ? 142 VAL A CB     1 
ATOM   816  C  CG1    . VAL A 1  112 ? 4.85078   12.23921  34.03245  1.000 23.14902  ? 142 VAL A CG1    1 
ATOM   817  C  CG2    . VAL A 1  112 ? 6.67127   10.85207  33.04096  1.000 19.52115  ? 142 VAL A CG2    1 
ATOM   818  N  N      . HIS A 1  113 ? 6.05642   15.28101  32.38151  1.000 22.34510  ? 143 HIS A N      1 
ATOM   819  C  CA     . HIS A 1  113 ? 5.50219   16.60916  32.61134  1.000 26.70616  ? 143 HIS A CA     1 
ATOM   820  C  C      . HIS A 1  113 ? 4.86037   17.15620  31.35209  1.000 25.57732  ? 143 HIS A C      1 
ATOM   821  O  O      . HIS A 1  113 ? 3.73342   17.66477  31.39392  1.000 26.64598  ? 143 HIS A O      1 
ATOM   822  C  CB     . HIS A 1  113 ? 6.59933   17.54519  33.08701  1.000 25.30806  ? 143 HIS A CB     1 
ATOM   823  C  CG     . HIS A 1  113 ? 6.22765   18.99196  33.02026  1.000 25.34609  ? 143 HIS A CG     1 
ATOM   824  N  ND1    . HIS A 1  113 ? 5.21199   19.53304  33.77320  1.000 32.34176  ? 143 HIS A ND1    1 
ATOM   825  C  CD2    . HIS A 1  113 ? 6.74722   20.00866  32.29414  1.000 34.29622  ? 143 HIS A CD2    1 
ATOM   826  C  CE1    . HIS A 1  113 ? 5.11615   20.82673  33.51121  1.000 32.60168  ? 143 HIS A CE1    1 
ATOM   827  N  NE2    . HIS A 1  113 ? 6.03437   21.13837  32.61450  1.000 35.80557  ? 143 HIS A NE2    1 
ATOM   828  N  N      . ARG A 1  114 ? 5.52667   16.99708  30.21456  1.000 28.11259  ? 144 ARG A N      1 
ATOM   829  C  CA     . ARG A 1  114 ? 5.05711   17.70000  29.02397  1.000 27.85134  ? 144 ARG A CA     1 
ATOM   830  C  C      . ARG A 1  114 ? 3.97966   16.91744  28.29272  1.000 38.18569  ? 144 ARG A C      1 
ATOM   831  O  O      . ARG A 1  114 ? 3.04926   17.50357  27.73256  1.000 28.19610  ? 144 ARG A O      1 
ATOM   832  C  CB     . ARG A 1  114 ? 6.21917   17.97180  28.07340  1.000 25.88678  ? 144 ARG A CB     1 
ATOM   833  C  CG     . ARG A 1  114 ? 7.24092   18.99630  28.54947  1.000 34.81018  ? 144 ARG A CG     1 
ATOM   834  C  CD     . ARG A 1  114 ? 8.23375   19.27734  27.42712  1.000 36.36897  ? 144 ARG A CD     1 
ATOM   835  N  NE     . ARG A 1  114 ? 9.31442   20.15791  27.85174  1.000 41.96449  ? 144 ARG A NE     1 
ATOM   836  C  CZ     . ARG A 1  114 ? 9.19672   21.47372  27.97026  1.000 54.38599  ? 144 ARG A CZ     1 
ATOM   837  N  NH1    . ARG A 1  114 ? 8.10705   22.10761  27.56529  1.000 58.39462  ? 144 ARG A NH1    1 
ATOM   838  N  NH2    . ARG A 1  114 ? 10.20787  22.17476  28.47826  1.000 42.88076  ? 144 ARG A NH2    1 
ATOM   839  N  N      . PHE A 1  115 ? 4.10789   15.59815  28.25810  1.000 25.50408  ? 145 PHE A N      1 
ATOM   840  C  CA     . PHE A 1  115 ? 3.27982   14.78967  27.39349  1.000 27.38364  ? 145 PHE A CA     1 
ATOM   841  C  C      . PHE A 1  115 ? 2.40673   13.77910  28.11044  1.000 38.27725  ? 145 PHE A C      1 
ATOM   842  O  O      . PHE A 1  115 ? 1.49129   13.23393  27.47991  1.000 35.31889  ? 145 PHE A O      1 
ATOM   843  C  CB     . PHE A 1  115 ? 4.15721   14.07916  26.35623  1.000 32.95599  ? 145 PHE A CB     1 
ATOM   844  C  CG     . PHE A 1  115 ? 5.00561   15.01924  25.55581  1.000 36.30245  ? 145 PHE A CG     1 
ATOM   845  C  CD1    . PHE A 1  115 ? 4.42793   15.87037  24.61641  1.000 37.01554  ? 145 PHE A CD1    1 
ATOM   846  C  CD2    . PHE A 1  115 ? 6.37118   15.09023  25.75838  1.000 32.67823  ? 145 PHE A CD2    1 
ATOM   847  C  CE1    . PHE A 1  115 ? 5.20370   16.75133  23.88367  1.000 36.79099  ? 145 PHE A CE1    1 
ATOM   848  C  CE2    . PHE A 1  115 ? 7.15299   15.96395  25.02359  1.000 36.03654  ? 145 PHE A CE2    1 
ATOM   849  C  CZ     . PHE A 1  115 ? 6.56693   16.79617  24.07986  1.000 33.98175  ? 145 PHE A CZ     1 
ATOM   850  N  N      . CYS A 1  116 ? 2.61510   13.53985  29.40363  1.000 28.39324  ? 146 CYS A N      1 
ATOM   851  C  CA     . CYS A 1  116 ? 1.77648   12.55847  30.07357  1.000 26.27876  ? 146 CYS A CA     1 
ATOM   852  C  C      . CYS A 1  116 ? 1.48831   12.95258  31.51281  1.000 27.59691  ? 146 CYS A C      1 
ATOM   853  O  O      . CYS A 1  116 ? 1.69332   12.15065  32.43589  1.000 28.00157  ? 146 CYS A O      1 
ATOM   854  C  CB     . CYS A 1  116 ? 2.43585   11.18347  30.02983  1.000 31.08939  ? 146 CYS A CB     1 
ATOM   855  S  SG     . CYS A 1  116 ? 1.27698   9.81478   30.23123  1.000 33.54373  ? 146 CYS A SG     1 
ATOM   856  N  N      . PRO A 1  117 ? 1.02535   14.17838  31.75624  1.000 27.82194  ? 147 PRO A N      1 
ATOM   857  C  CA     . PRO A 1  117 ? 0.68137   14.56717  33.12806  1.000 28.98115  ? 147 PRO A CA     1 
ATOM   858  C  C      . PRO A 1  117 ? -0.51866  13.82058  33.66930  1.000 28.26054  ? 147 PRO A C      1 
ATOM   859  O  O      . PRO A 1  117 ? -0.78418  13.88348  34.87832  1.000 33.52196  ? 147 PRO A O      1 
ATOM   860  C  CB     . PRO A 1  117 ? 0.39023   16.06633  32.98998  1.000 32.30055  ? 147 PRO A CB     1 
ATOM   861  C  CG     . PRO A 1  117 ? -0.16134  16.17073  31.61236  1.000 33.52086  ? 147 PRO A CG     1 
ATOM   862  C  CD     . PRO A 1  117 ? 0.70771   15.25124  30.79418  1.000 33.37647  ? 147 PRO A CD     1 
ATOM   863  N  N      . GLN A 1  118 ? -1.22270  13.07939  32.81683  1.000 30.16290  ? 148 GLN A N      1 
ATOM   864  C  CA     . GLN A 1  118 ? -2.36826  12.29022  33.25158  1.000 34.88302  ? 148 GLN A CA     1 
ATOM   865  C  C      . GLN A 1  118 ? -1.96849  10.98796  33.95048  1.000 34.11518  ? 148 GLN A C      1 
ATOM   866  O  O      . GLN A 1  118 ? -2.80468  10.38697  34.63678  1.000 31.93503  ? 148 GLN A O      1 
ATOM   867  C  CB     . GLN A 1  118 ? -3.25262  11.97612  32.04040  1.000 35.76138  ? 148 GLN A CB     1 
ATOM   868  C  CG     . GLN A 1  118 ? -3.81206  13.21290  31.32658  1.000 38.69067  ? 148 GLN A CG     1 
ATOM   869  C  CD     . GLN A 1  118 ? -2.85880  13.82222  30.30728  1.000 43.99800  ? 148 GLN A CD     1 
ATOM   870  O  OE1    . GLN A 1  118 ? -1.74336  13.33797  30.10231  1.000 35.77081  ? 148 GLN A OE1    1 
ATOM   871  N  NE2    . GLN A 1  118 ? -3.30150  14.89757  29.65696  1.000 43.73657  ? 148 GLN A NE2    1 
ATOM   872  N  N      . ALA A 1  119 ? -0.71417  10.55615  33.82388  1.000 27.06434  ? 149 ALA A N      1 
ATOM   873  C  CA     . ALA A 1  119 ? -0.28057  9.30631   34.45368  1.000 22.37709  ? 149 ALA A CA     1 
ATOM   874  C  C      . ALA A 1  119 ? -0.54952  9.32343   35.95153  1.000 21.82179  ? 149 ALA A C      1 
ATOM   875  O  O      . ALA A 1  119 ? -0.15843  10.25857  36.65944  1.000 23.26829  ? 149 ALA A O      1 
ATOM   876  C  CB     . ALA A 1  119 ? 1.21183   9.07814   34.19490  1.000 27.76082  ? 149 ALA A CB     1 
ATOM   877  N  N      . ALA A 1  120 ? -1.22745  8.28582   36.45405  1.000 21.90717  ? 150 ALA A N      1 
ATOM   878  C  CA     . ALA A 1  120 ? -1.41008  8.21777   37.90178  1.000 22.79014  ? 150 ALA A CA     1 
ATOM   879  C  C      . ALA A 1  120 ? -0.08242  7.96558   38.60895  1.000 24.09269  ? 150 ALA A C      1 
ATOM   880  O  O      . ALA A 1  120 ? 0.22891   8.61662   39.61872  1.000 20.70539  ? 150 ALA A O      1 
ATOM   881  C  CB     . ALA A 1  120 ? -2.40218  7.13038   38.28236  1.000 24.70466  ? 150 ALA A CB     1 
ATOM   882  N  N      . PHE A 1  121 ? 0.71004   7.03280   38.08286  1.000 24.21318  ? 151 PHE A N      1 
ATOM   883  C  CA     . PHE A 1  121 ? 1.98547   6.65838   38.69140  1.000 19.83184  ? 151 PHE A CA     1 
ATOM   884  C  C      . PHE A 1  121 ? 2.99440   6.42219   37.58340  1.000 19.07374  ? 151 PHE A C      1 
ATOM   885  O  O      . PHE A 1  121 ? 2.64573   6.02044   36.46576  1.000 21.94617  ? 151 PHE A O      1 
ATOM   886  C  CB     . PHE A 1  121 ? 1.86189   5.40503   39.60095  1.000 18.48952  ? 151 PHE A CB     1 
ATOM   887  C  CG     . PHE A 1  121 ? 0.95365   5.60436   40.77167  1.000 22.78874  ? 151 PHE A CG     1 
ATOM   888  C  CD1    . PHE A 1  121 ? 1.39399   6.22949   41.92027  1.000 25.07355  ? 151 PHE A CD1    1 
ATOM   889  C  CD2    . PHE A 1  121 ? -0.39368  5.20329   40.69691  1.000 25.30132  ? 151 PHE A CD2    1 
ATOM   890  C  CE1    . PHE A 1  121 ? 0.53608   6.44368   42.99735  1.000 26.24566  ? 151 PHE A CE1    1 
ATOM   891  C  CE2    . PHE A 1  121 ? -1.23992  5.41107   41.75357  1.000 27.31214  ? 151 PHE A CE2    1 
ATOM   892  C  CZ     . PHE A 1  121 ? -0.79278  6.02732   42.90739  1.000 28.37300  ? 151 PHE A CZ     1 
ATOM   893  N  N      . VAL A 1  122 ? 4.26126   6.67006   37.92371  1.000 21.66010  ? 152 VAL A N      1 
ATOM   894  C  CA     . VAL A 1  122 ? 5.39196   6.51068   37.02472  1.000 19.78929  ? 152 VAL A CA     1 
ATOM   895  C  C      . VAL A 1  122 ? 6.45806   5.73761   37.79097  1.000 17.83110  ? 152 VAL A C      1 
ATOM   896  O  O      . VAL A 1  122 ? 6.73451   6.04912   38.95362  1.000 17.60317  ? 152 VAL A O      1 
ATOM   897  C  CB     . VAL A 1  122 ? 5.94907   7.87794   36.57140  1.000 23.46321  ? 152 VAL A CB     1 
ATOM   898  C  CG1    . VAL A 1  122 ? 7.14651   7.70193   35.60581  1.000 20.63917  ? 152 VAL A CG1    1 
ATOM   899  C  CG2    . VAL A 1  122 ? 4.82399   8.74496   35.94414  1.000 22.23148  ? 152 VAL A CG2    1 
ATOM   900  N  N      . MET A 1  123 ? 7.05165   4.74230   37.15271  1.000 19.17821  ? 153 MET A N      1 
ATOM   901  C  CA     . MET A 1  123 ? 8.18490   4.03393   37.72993  1.000 19.01957  ? 153 MET A CA     1 
ATOM   902  C  C      . MET A 1  123 ? 9.38523   4.24509   36.82443  1.000 18.35417  ? 153 MET A C      1 
ATOM   903  O  O      . MET A 1  123 ? 9.32684   3.94359   35.63317  1.000 23.03315  ? 153 MET A O      1 
ATOM   904  C  CB     . MET A 1  123 ? 7.89972   2.52774   37.88757  1.000 15.80273  ? 153 MET A CB     1 
ATOM   905  C  CG     . MET A 1  123 ? 9.12417   1.76390   38.42793  1.000 17.61017  ? 153 MET A CG     1 
ATOM   906  S  SD     . MET A 1  123 ? 8.66394   0.08701   38.86185  1.000 21.95863  ? 153 MET A SD     1 
ATOM   907  C  CE     . MET A 1  123 ? 10.09247  -0.45511  39.78593  1.000 24.90891  ? 153 MET A CE     1 
ATOM   908  N  N      . LYS A 1  124 ? 10.47444  4.75295   37.38510  1.000 16.51076  ? 154 LYS A N      1 
ATOM   909  C  CA     . LYS A 1  124 ? 11.72922  4.81312   36.65721  1.000 19.43819  ? 154 LYS A CA     1 
ATOM   910  C  C      . LYS A 1  124 ? 12.54676  3.59613   37.07949  1.000 21.14827  ? 154 LYS A C      1 
ATOM   911  O  O      . LYS A 1  124 ? 12.68951  3.34242   38.27659  1.000 17.50381  ? 154 LYS A O      1 
ATOM   912  C  CB     . LYS A 1  124 ? 12.47098  6.11103   36.97936  1.000 16.26438  ? 154 LYS A CB     1 
ATOM   913  C  CG     . LYS A 1  124 ? 13.81598  6.27230   36.29203  1.000 21.41916  ? 154 LYS A CG     1 
ATOM   914  C  CD     . LYS A 1  124 ? 14.92495  5.92775   37.30078  1.000 27.90391  ? 154 LYS A CD     1 
ATOM   915  C  CE     . LYS A 1  124 ? 16.19429  5.55656   36.61441  1.000 30.99639  ? 154 LYS A CE     1 
ATOM   916  N  NZ     . LYS A 1  124 ? 17.21826  5.07794   37.57666  1.000 29.53750  ? 154 LYS A NZ     1 
ATOM   917  N  N      . THR A 1  125 ? 13.03017  2.82023   36.10711  1.000 19.86494  ? 155 THR A N      1 
ATOM   918  C  CA     . THR A 1  125 ? 13.68883  1.56507   36.45375  1.000 19.44259  ? 155 THR A CA     1 
ATOM   919  C  C      . THR A 1  125 ? 14.89897  1.28845   35.55762  1.000 21.11051  ? 155 THR A C      1 
ATOM   920  O  O      . THR A 1  125 ? 14.97751  1.73930   34.40737  1.000 21.26620  ? 155 THR A O      1 
ATOM   921  C  CB     . THR A 1  125 ? 12.69392  0.38430   36.40807  1.000 19.98438  ? 155 THR A CB     1 
ATOM   922  O  OG1    . THR A 1  125 ? 13.33266  -0.79908  36.91634  1.000 27.34056  ? 155 THR A OG1    1 
ATOM   923  C  CG2    . THR A 1  125 ? 12.18796  0.12186   34.99277  1.000 22.03778  ? 155 THR A CG2    1 
ATOM   924  N  N      . ASP A 1  126 ? 15.83761  0.52645   36.11715  1.000 19.08359  ? 156 ASP A N      1 
ATOM   925  C  CA     . ASP A 1  126 ? 16.97333  -0.05027  35.40530  1.000 18.95487  ? 156 ASP A CA     1 
ATOM   926  C  C      . ASP A 1  126 ? 16.48227  -1.13134  34.44045  1.000 20.35077  ? 156 ASP A C      1 
ATOM   927  O  O      . ASP A 1  126 ? 15.36511  -1.64785  34.54229  1.000 18.65151  ? 156 ASP A O      1 
ATOM   928  C  CB     . ASP A 1  126 ? 17.96323  -0.73380  36.37199  1.000 21.15590  ? 156 ASP A CB     1 
ATOM   929  C  CG     . ASP A 1  126 ? 19.08105  0.16866   36.92289  1.000 33.29461  ? 156 ASP A CG     1 
ATOM   930  O  OD1    . ASP A 1  126 ? 18.93987  1.40018   37.01272  1.000 24.75122  ? 156 ASP A OD1    1 
ATOM   931  O  OD2    . ASP A 1  126 ? 20.13999  -0.42285  37.30806  1.000 32.21351  ? 156 ASP A OD2    1 
ATOM   932  N  N      . SER A 1  127 ? 17.36473  -1.54444  33.54597  1.000 20.44980  ? 157 SER A N      1 
ATOM   933  C  CA     . SER A 1  127 ? 16.98963  -2.58267  32.59298  1.000 23.56383  ? 157 SER A CA     1 
ATOM   934  C  C      . SER A 1  127 ? 17.32199  -3.98581  33.08376  1.000 25.02392  ? 157 SER A C      1 
ATOM   935  O  O      . SER A 1  127 ? 16.74638  -4.95914  32.56543  1.000 22.95487  ? 157 SER A O      1 
ATOM   936  C  CB     . SER A 1  127 ? 17.65335  -2.31744  31.23855  1.000 21.76231  ? 157 SER A CB     1 
ATOM   937  O  OG     . SER A 1  127 ? 19.05347  -2.13286  31.41876  1.000 26.43928  ? 157 SER A OG     1 
ATOM   938  N  N      . ASP A 1  128 ? 18.25382  -4.12672  34.02910  1.000 19.25510  ? 158 ASP A N      1 
ATOM   939  C  CA     . ASP A 1  128 ? 18.59679  -5.45697  34.55940  1.000 19.52100  ? 158 ASP A CA     1 
ATOM   940  C  C      . ASP A 1  128 ? 17.72232  -5.77461  35.77584  1.000 20.15024  ? 158 ASP A C      1 
ATOM   941  O  O      . ASP A 1  128 ? 18.17969  -6.04666  36.88377  1.000 19.46453  ? 158 ASP A O      1 
ATOM   942  C  CB     . ASP A 1  128 ? 20.09105  -5.55228  34.86069  1.000 23.07984  ? 158 ASP A CB     1 
ATOM   943  C  CG     . ASP A 1  128 ? 20.60314  -4.44969  35.79323  1.000 31.25824  ? 158 ASP A CG     1 
ATOM   944  O  OD1    . ASP A 1  128 ? 20.00214  -3.36589  35.87824  1.000 26.57411  ? 158 ASP A OD1    1 
ATOM   945  O  OD2    . ASP A 1  128 ? 21.65866  -4.66545  36.40598  1.000 33.21890  ? 158 ASP A OD2    1 
ATOM   946  N  N      . MET A 1  129 ? 16.40966  -5.75386  35.52486  1.000 18.92978  ? 159 MET A N      1 
ATOM   947  C  CA     . MET A 1  129 ? 15.40610  -5.80295  36.57860  1.000 21.57958  ? 159 MET A CA     1 
ATOM   948  C  C      . MET A 1  129 ? 14.29305  -6.77944  36.22746  1.000 18.95654  ? 159 MET A C      1 
ATOM   949  O  O      . MET A 1  129 ? 13.94416  -6.94414  35.06150  1.000 18.10809  ? 159 MET A O      1 
ATOM   950  C  CB     . MET A 1  129 ? 14.73887  -4.42987  36.79839  1.000 19.20286  ? 159 MET A CB     1 
ATOM   951  C  CG     . MET A 1  129 ? 15.67221  -3.32688  37.30283  1.000 17.44961  ? 159 MET A CG     1 
ATOM   952  S  SD     . MET A 1  129 ? 16.16875  -3.50106  39.01325  1.000 20.14562  ? 159 MET A SD     1 
ATOM   953  C  CE     . MET A 1  129 ? 14.61521  -3.22569  39.84672  1.000 19.47052  ? 159 MET A CE     1 
ATOM   954  N  N      . PHE A 1  130 ? 13.70250  -7.35304  37.26447  1.000 18.86134  ? 160 PHE A N      1 
ATOM   955  C  CA     . PHE A 1  130 ? 12.38699  -7.97800  37.21242  1.000 17.14329  ? 160 PHE A CA     1 
ATOM   956  C  C      . PHE A 1  130 ? 11.41446  -7.05828  37.93410  1.000 15.57630  ? 160 PHE A C      1 
ATOM   957  O  O      . PHE A 1  130 ? 11.68770  -6.63915  39.05959  1.000 16.37047  ? 160 PHE A O      1 
ATOM   958  C  CB     . PHE A 1  130 ? 12.37827  -9.35329  37.89431  1.000 17.85272  ? 160 PHE A CB     1 
ATOM   959  C  CG     . PHE A 1  130 ? 10.96131  -9.86169  38.19377  1.000 20.55806  ? 160 PHE A CG     1 
ATOM   960  C  CD1    . PHE A 1  130 ? 10.25245  -10.53425 37.24084  1.000 22.80116  ? 160 PHE A CD1    1 
ATOM   961  C  CD2    . PHE A 1  130 ? 10.38412  -9.65019  39.43314  1.000 18.43808  ? 160 PHE A CD2    1 
ATOM   962  C  CE1    . PHE A 1  130 ? 8.94044   -10.99041 37.49149  1.000 22.52189  ? 160 PHE A CE1    1 
ATOM   963  C  CE2    . PHE A 1  130 ? 9.10233   -10.11758 39.71459  1.000 20.82021  ? 160 PHE A CE2    1 
ATOM   964  C  CZ     . PHE A 1  130 ? 8.37881   -10.78572 38.72104  1.000 18.97470  ? 160 PHE A CZ     1 
ATOM   965  N  N      . ILE A 1  131 ? 10.28011  -6.75788  37.30016  1.000 17.89136  ? 161 ILE A N      1 
ATOM   966  C  CA     A ILE A 1  131 ? 9.24244   -5.90630  37.87974  0.560 18.99594  ? 161 ILE A CA     1 
ATOM   967  C  CA     B ILE A 1  131 ? 9.25179   -5.91805  37.90067  0.440 18.99035  ? 161 ILE A CA     1 
ATOM   968  C  C      . ILE A 1  131 ? 7.94516   -6.69754  37.90565  1.000 19.24981  ? 161 ILE A C      1 
ATOM   969  O  O      . ILE A 1  131 ? 7.55178   -7.27444  36.88408  1.000 17.96738  ? 161 ILE A O      1 
ATOM   970  C  CB     A ILE A 1  131 ? 9.03054   -4.60691  37.07944  0.560 18.00357  ? 161 ILE A CB     1 
ATOM   971  C  CB     B ILE A 1  131 ? 9.09353   -4.57943  37.15557  0.440 18.04983  ? 161 ILE A CB     1 
ATOM   972  C  CG1    A ILE A 1  131 ? 10.32564  -3.80280  36.96595  0.560 19.72927  ? 161 ILE A CG1    1 
ATOM   973  C  CG1    B ILE A 1  131 ? 10.38061  -3.75387  37.28358  0.440 19.98484  ? 161 ILE A CG1    1 
ATOM   974  C  CG2    A ILE A 1  131 ? 7.93230   -3.75599  37.74613  0.560 17.93735  ? 161 ILE A CG2    1 
ATOM   975  C  CG2    B ILE A 1  131 ? 7.90047   -3.79579  37.72074  0.440 17.96242  ? 161 ILE A CG2    1 
ATOM   976  C  CD1    A ILE A 1  131 ? 10.93983  -3.44639  38.30924  0.560 16.27671  ? 161 ILE A CD1    1 
ATOM   977  C  CD1    B ILE A 1  131 ? 10.40338  -2.47724  36.46846  0.440 15.70596  ? 161 ILE A CD1    1 
ATOM   978  N  N      . ASN A 1  132 ? 7.29088   -6.73023  39.05855  1.000 18.19632  ? 162 ASN A N      1 
ATOM   979  C  CA     . ASN A 1  132 ? 5.99540   -7.40423  39.18763  1.000 18.74022  ? 162 ASN A CA     1 
ATOM   980  C  C      . ASN A 1  132 ? 4.94996   -6.29179  39.15426  1.000 19.77022  ? 162 ASN A C      1 
ATOM   981  O  O      . ASN A 1  132 ? 4.58370   -5.72572  40.17915  1.000 18.36503  ? 162 ASN A O      1 
ATOM   982  C  CB     . ASN A 1  132 ? 5.89540   -8.23136  40.46111  1.000 20.07618  ? 162 ASN A CB     1 
ATOM   983  C  CG     . ASN A 1  132 ? 4.61744   -9.05217  40.49932  1.000 24.42232  ? 162 ASN A CG     1 
ATOM   984  O  OD1    . ASN A 1  132 ? 3.65371   -8.69668  39.83302  1.000 22.62444  ? 162 ASN A OD1    1 
ATOM   985  N  ND2    . ASN A 1  132 ? 4.60702   -10.14773 41.26283  1.000 22.82516  ? 162 ASN A ND2    1 
ATOM   986  N  N      . VAL A 1  133 ? 4.49120   -5.98531  37.94849  1.000 19.61095  ? 163 VAL A N      1 
ATOM   987  C  CA     . VAL A 1  133 ? 3.53680   -4.89963  37.76924  1.000 25.62070  ? 163 VAL A CA     1 
ATOM   988  C  C      . VAL A 1  133 ? 2.19663   -5.23121  38.41202  1.000 26.40731  ? 163 VAL A C      1 
ATOM   989  O  O      . VAL A 1  133 ? 1.50463   -4.33425  38.90738  1.000 24.92031  ? 163 VAL A O      1 
ATOM   990  C  CB     . VAL A 1  133 ? 3.38793   -4.60066  36.27274  1.000 24.36015  ? 163 VAL A CB     1 
ATOM   991  C  CG1    . VAL A 1  133 ? 2.23224   -3.61530  36.04825  1.000 26.96278  ? 163 VAL A CG1    1 
ATOM   992  C  CG2    . VAL A 1  133 ? 4.70640   -4.02904  35.71951  1.000 19.59648  ? 163 VAL A CG2    1 
ATOM   993  N  N      . ASP A 1  134 ? 1.80384   -6.50911  38.42083  1.000 26.65668  ? 164 ASP A N      1 
ATOM   994  C  CA     . ASP A 1  134 ? 0.53104   -6.88627  39.03265  1.000 25.20348  ? 164 ASP A CA     1 
ATOM   995  C  C      . ASP A 1  134 ? 0.51629   -6.56262  40.51831  1.000 25.63761  ? 164 ASP A C      1 
ATOM   996  O  O      . ASP A 1  134 ? -0.41843  -5.91901  41.03148  1.000 28.63931  ? 164 ASP A O      1 
ATOM   997  C  CB     . ASP A 1  134 ? 0.26513   -8.38418  38.79520  1.000 29.45888  ? 164 ASP A CB     1 
ATOM   998  C  CG     . ASP A 1  134 ? 0.33986   -8.76044  37.31865  1.000 39.67907  ? 164 ASP A CG     1 
ATOM   999  O  OD1    . ASP A 1  134 ? 1.44786   -9.08473  36.83318  1.000 44.52252  ? 164 ASP A OD1    1 
ATOM   1000 O  OD2    . ASP A 1  134 ? -0.70599  -8.71966  36.63342  1.000 39.94764  ? 164 ASP A OD2    1 
ATOM   1001 N  N      . TYR A 1  135 ? 1.57003   -6.97167  41.22745  1.000 20.19826  ? 165 TYR A N      1 
ATOM   1002 C  CA     . TYR A 1  135 ? 1.63252   -6.72094  42.65924  1.000 18.04537  ? 165 TYR A CA     1 
ATOM   1003 C  C      . TYR A 1  135 ? 1.83122   -5.23969  42.94466  1.000 21.06633  ? 165 TYR A C      1 
ATOM   1004 O  O      . TYR A 1  135 ? 1.27935   -4.71904  43.92189  1.000 22.95366  ? 165 TYR A O      1 
ATOM   1005 C  CB     . TYR A 1  135 ? 2.76091   -7.54048  43.29194  1.000 19.01163  ? 165 TYR A CB     1 
ATOM   1006 C  CG     . TYR A 1  135 ? 2.71192   -7.61238  44.80328  1.000 21.61223  ? 165 TYR A CG     1 
ATOM   1007 C  CD1    . TYR A 1  135 ? 1.58193   -8.08981  45.45682  1.000 23.52342  ? 165 TYR A CD1    1 
ATOM   1008 C  CD2    . TYR A 1  135 ? 3.78163   -7.23316  45.56230  1.000 18.47269  ? 165 TYR A CD2    1 
ATOM   1009 C  CE1    . TYR A 1  135 ? 1.53379   -8.16481  46.82901  1.000 27.02634  ? 165 TYR A CE1    1 
ATOM   1010 C  CE2    . TYR A 1  135 ? 3.75338   -7.30835  46.94878  1.000 21.80604  ? 165 TYR A CE2    1 
ATOM   1011 C  CZ     . TYR A 1  135 ? 2.62153   -7.77929  47.57645  1.000 25.77563  ? 165 TYR A CZ     1 
ATOM   1012 O  OH     . TYR A 1  135 ? 2.58692   -7.84846  48.95382  1.000 33.37312  ? 165 TYR A OH     1 
ATOM   1013 N  N      . LEU A 1  136 ? 2.64883   -4.55405  42.12613  1.000 19.91277  ? 166 LEU A N      1 
ATOM   1014 C  CA     . LEU A 1  136 ? 2.82170   -3.11014  42.30319  1.000 20.52472  ? 166 LEU A CA     1 
ATOM   1015 C  C      . LEU A 1  136 ? 1.48588   -2.38398  42.17263  1.000 23.97236  ? 166 LEU A C      1 
ATOM   1016 O  O      . LEU A 1  136 ? 1.16660   -1.49420  42.96198  1.000 23.49823  ? 166 LEU A O      1 
ATOM   1017 C  CB     . LEU A 1  136 ? 3.77893   -2.55371  41.25891  1.000 19.04738  ? 166 LEU A CB     1 
ATOM   1018 C  CG     . LEU A 1  136 ? 3.93363   -1.00849  41.25836  1.000 21.83225  ? 166 LEU A CG     1 
ATOM   1019 C  CD1    . LEU A 1  136 ? 4.34953   -0.47230  42.60907  1.000 20.04667  ? 166 LEU A CD1    1 
ATOM   1020 C  CD2    . LEU A 1  136 ? 4.93833   -0.61986  40.20295  1.000 20.16742  ? 166 LEU A CD2    1 
ATOM   1021 N  N      . THR A 1  137 ? 0.73805   -2.70887  41.13149  1.000 25.33577  ? 167 THR A N      1 
ATOM   1022 C  CA     . THR A 1  137 ? -0.56994  -2.09156  40.91854  1.000 25.50183  ? 167 THR A CA     1 
ATOM   1023 C  C      . THR A 1  137 ? -1.48613  -2.33966  42.10931  1.000 28.04602  ? 167 THR A C      1 
ATOM   1024 O  O      . THR A 1  137 ? -2.16195  -1.41878  42.59060  1.000 31.42900  ? 167 THR A O      1 
ATOM   1025 C  CB     . THR A 1  137 ? -1.17863  -2.63585  39.62910  1.000 24.33541  ? 167 THR A CB     1 
ATOM   1026 O  OG1    . THR A 1  137 ? -0.42429  -2.15255  38.51028  1.000 28.82221  ? 167 THR A OG1    1 
ATOM   1027 C  CG2    . THR A 1  137 ? -2.64652  -2.19236  39.47740  1.000 31.51980  ? 167 THR A CG2    1 
ATOM   1028 N  N      . GLU A 1  138 ? -1.54283  -3.59013  42.58325  1.000 28.93816  ? 168 GLU A N      1 
ATOM   1029 C  CA     . GLU A 1  138 ? -2.34556  -3.90247  43.76566  1.000 29.39448  ? 168 GLU A CA     1 
ATOM   1030 C  C      . GLU A 1  138 ? -1.94284  -3.04857  44.96620  1.000 34.28894  ? 168 GLU A C      1 
ATOM   1031 O  O      . GLU A 1  138 ? -2.80318  -2.48073  45.66177  1.000 33.98082  ? 168 GLU A O      1 
ATOM   1032 C  CB     . GLU A 1  138 ? -2.21847  -5.39843  44.08185  1.000 30.12595  ? 168 GLU A CB     1 
ATOM   1033 C  CG     . GLU A 1  138 ? -2.61814  -5.79245  45.48093  1.000 35.80421  ? 168 GLU A CG     1 
ATOM   1034 C  CD     . GLU A 1  138 ? -2.45929  -7.28680  45.71902  1.000 39.75532  ? 168 GLU A CD     1 
ATOM   1035 O  OE1    . GLU A 1  138 ? -2.34415  -8.02713  44.72099  1.000 41.04253  ? 168 GLU A OE1    1 
ATOM   1036 O  OE2    . GLU A 1  138 ? -2.43108  -7.70744  46.89375  1.000 45.05134  ? 168 GLU A OE2    1 
ATOM   1037 N  N      . LEU A 1  139 ? -0.63254  -2.89835  45.20270  1.000 26.03827  ? 169 LEU A N      1 
ATOM   1038 C  CA     . LEU A 1  139 ? -0.18996  -2.12445  46.35763  1.000 27.80407  ? 169 LEU A CA     1 
ATOM   1039 C  C      . LEU A 1  139 ? -0.48257  -0.63472  46.17576  1.000 31.43514  ? 169 LEU A C      1 
ATOM   1040 O  O      . LEU A 1  139 ? -0.85594  0.04884   47.13498  1.000 33.82332  ? 169 LEU A O      1 
ATOM   1041 C  CB     . LEU A 1  139 ? 1.30770   -2.35263  46.61016  1.000 26.73395  ? 169 LEU A CB     1 
ATOM   1042 C  CG     . LEU A 1  139 ? 1.68857   -3.77039  47.09000  1.000 27.80652  ? 169 LEU A CG     1 
ATOM   1043 C  CD1    . LEU A 1  139 ? 3.22080   -3.88929  47.33576  1.000 22.98055  ? 169 LEU A CD1    1 
ATOM   1044 C  CD2    . LEU A 1  139 ? 0.92545   -4.11394  48.34332  1.000 31.47635  ? 169 LEU A CD2    1 
ATOM   1045 N  N      . LEU A 1  140 ? -0.31797  -0.11697  44.95617  1.000 30.78345  ? 170 LEU A N      1 
ATOM   1046 C  CA     . LEU A 1  140 ? -0.61039  1.29400   44.70192  1.000 27.08254  ? 170 LEU A CA     1 
ATOM   1047 C  C      . LEU A 1  140 ? -2.09995  1.58717   44.86977  1.000 35.69359  ? 170 LEU A C      1 
ATOM   1048 O  O      . LEU A 1  140 ? -2.47619  2.61143   45.45197  1.000 35.73516  ? 170 LEU A O      1 
ATOM   1049 C  CB     . LEU A 1  140 ? -0.15195  1.68072   43.29859  1.000 29.51021  ? 170 LEU A CB     1 
ATOM   1050 C  CG     . LEU A 1  140 ? 1.36094   1.71219   43.04043  1.000 23.00727  ? 170 LEU A CG     1 
ATOM   1051 C  CD1    . LEU A 1  140 ? 1.59243   1.84551   41.54736  1.000 18.01501  ? 170 LEU A CD1    1 
ATOM   1052 C  CD2    . LEU A 1  140 ? 2.02361   2.86918   43.81449  1.000 23.53472  ? 170 LEU A CD2    1 
ATOM   1053 N  N      . LEU A 1  141 ? -2.95886  0.69455   44.36707  1.000 37.87224  ? 171 LEU A N      1 
ATOM   1054 C  CA     . LEU A 1  141 ? -4.39848  0.87770   44.52223  1.000 37.25480  ? 171 LEU A CA     1 
ATOM   1055 C  C      . LEU A 1  141 ? -4.78836  0.82930   45.98777  1.000 38.01241  ? 171 LEU A C      1 
ATOM   1056 O  O      . LEU A 1  141 ? -5.76352  1.47321   46.39648  1.000 45.76511  ? 171 LEU A O      1 
ATOM   1057 C  CB     . LEU A 1  141 ? -5.15579  -0.17495  43.70787  1.000 34.07260  ? 171 LEU A CB     1 
ATOM   1058 C  CG     . LEU A 1  141 ? -5.07637  0.05029   42.19589  1.000 31.63377  ? 171 LEU A CG     1 
ATOM   1059 C  CD1    . LEU A 1  141 ? -5.57943  -1.15954  41.41963  1.000 40.40845  ? 171 LEU A CD1    1 
ATOM   1060 C  CD2    . LEU A 1  141 ? -5.86872  1.30815   41.81016  1.000 38.60880  ? 171 LEU A CD2    1 
ATOM   1061 N  N      . LYS A 1  142 ? -4.03599  0.07745   46.79028  1.000 36.26956  ? 172 LYS A N      1 
ATOM   1062 C  CA     . LYS A 1  142 ? -4.29758  -0.00423  48.22142  1.000 38.29736  ? 172 LYS A CA     1 
ATOM   1063 C  C      . LYS A 1  142 ? -3.74256  1.17253   49.02125  1.000 49.36757  ? 172 LYS A C      1 
ATOM   1064 O  O      . LYS A 1  142 ? -4.21622  1.43855   50.13219  1.000 49.22146  ? 172 LYS A O      1 
ATOM   1065 C  CB     . LYS A 1  142 ? -3.71292  -1.30363  48.76886  1.000 48.75299  ? 172 LYS A CB     1 
ATOM   1066 C  CG     . LYS A 1  142 ? -3.81383  -1.43473  50.26845  1.000 54.60641  ? 172 LYS A CG     1 
ATOM   1067 C  CD     . LYS A 1  142 ? -2.69806  -2.31530  50.79753  1.000 58.22672  ? 172 LYS A CD     1 
ATOM   1068 C  CE     . LYS A 1  142 ? -2.50962  -3.55006  49.92272  1.000 59.48541  ? 172 LYS A CE     1 
ATOM   1069 N  NZ     . LYS A 1  142 ? -1.89759  -4.68066  50.68383  1.000 64.78704  ? 172 LYS A NZ     1 
ATOM   1070 N  N      . LYS A 1  143 ? -2.70094  1.83859   48.52518  1.000 45.50459  ? 173 LYS A N      1 
ATOM   1071 C  CA     . LYS A 1  143 ? -2.01926  2.84546   49.32778  1.000 48.88786  ? 173 LYS A CA     1 
ATOM   1072 C  C      . LYS A 1  143 ? -2.86069  4.10312   49.55427  1.000 43.63744  ? 173 LYS A C      1 
ATOM   1073 O  O      . LYS A 1  143 ? -2.65552  4.78935   50.56172  1.000 48.59313  ? 173 LYS A O      1 
ATOM   1074 C  CB     . LYS A 1  143 ? -0.67614  3.18782   48.66649  1.000 45.20376  ? 173 LYS A CB     1 
ATOM   1075 C  CG     . LYS A 1  143 ? 0.26508   3.96970   49.53901  1.000 44.34811  ? 173 LYS A CG     1 
ATOM   1076 C  CD     . LYS A 1  143 ? 0.91047   3.04529   50.54027  1.000 41.48167  ? 173 LYS A CD     1 
ATOM   1077 C  CE     . LYS A 1  143 ? 2.10981   3.68020   51.22921  1.000 34.76021  ? 173 LYS A CE     1 
ATOM   1078 N  NZ     . LYS A 1  143 ? 2.41995   2.96842   52.49706  1.000 47.50758  ? 173 LYS A NZ     1 
ATOM   1079 N  N      . ASN A 1  144 ? -3.80001  4.41358   48.65160  1.000 39.32471  ? 174 ASN A N      1 
ATOM   1080 C  CA     . ASN A 1  144 ? -4.65447  5.60575   48.74261  1.000 46.96773  ? 174 ASN A CA     1 
ATOM   1081 C  C      . ASN A 1  144 ? -3.80467  6.87447   48.75780  1.000 50.95163  ? 174 ASN A C      1 
ATOM   1082 O  O      . ASN A 1  144 ? -4.14726  7.85641   49.41529  1.000 50.91802  ? 174 ASN A O      1 
ATOM   1083 C  CB     . ASN A 1  144 ? -5.56688  5.59617   49.97929  1.000 50.70258  ? 174 ASN A CB     1 
ATOM   1084 C  CG     . ASN A 1  144 ? -6.40006  4.34184   50.10927  1.000 47.71196  ? 174 ASN A CG     1 
ATOM   1085 O  OD1    . ASN A 1  144 ? -6.86098  3.77151   49.12136  1.000 40.84709  ? 174 ASN A OD1    1 
ATOM   1086 N  ND2    . ASN A 1  144 ? -6.60291  3.90972   51.35106  1.000 54.25552  ? 174 ASN A ND2    1 
ATOM   1087 N  N      . ARG A 1  145 ? -2.69266  6.85766   48.02289  1.000 47.90626  ? 175 ARG A N      1 
ATOM   1088 C  CA     . ARG A 1  145 ? -1.78811  8.00724   47.90682  1.000 43.88958  ? 175 ARG A CA     1 
ATOM   1089 C  C      . ARG A 1  145 ? -1.68688  8.39627   46.43518  1.000 45.13660  ? 175 ARG A C      1 
ATOM   1090 O  O      . ARG A 1  145 ? -0.99348  7.72415   45.66659  1.000 49.01692  ? 175 ARG A O      1 
ATOM   1091 C  CB     . ARG A 1  145 ? -0.41603  7.68080   48.48975  1.000 41.20063  ? 175 ARG A CB     1 
ATOM   1092 C  CG     . ARG A 1  145 ? -0.42386  7.33098   49.98170  1.000 37.42597  ? 175 ARG A CG     1 
ATOM   1093 C  CD     . ARG A 1  145 ? -0.42456  8.56785   50.88170  1.000 55.68837  ? 175 ARG A CD     1 
ATOM   1094 N  NE     . ARG A 1  145 ? 0.77027   9.38568   50.70683  1.000 41.85328  ? 175 ARG A NE     1 
ATOM   1095 C  CZ     . ARG A 1  145 ? 0.84630   10.43504  49.90250  1.000 40.43626  ? 175 ARG A CZ     1 
ATOM   1096 N  NH1    . ARG A 1  145 ? -0.21947  10.90240  49.27447  1.000 35.58105  ? 175 ARG A NH1    1 
ATOM   1097 N  NH2    . ARG A 1  145 ? 2.01934   11.04458  49.74189  1.000 40.52938  ? 175 ARG A NH2    1 
ATOM   1098 N  N      . THR A 1  146 ? -2.38983  9.45956   46.03268  1.000 38.66300  ? 176 THR A N      1 
ATOM   1099 C  CA     . THR A 1  146 ? -2.44927  9.88541   44.63735  1.000 34.39756  ? 176 THR A CA     1 
ATOM   1100 C  C      . THR A 1  146 ? -1.62680  11.13560  44.31839  1.000 28.52424  ? 176 THR A C      1 
ATOM   1101 O  O      . THR A 1  146 ? -1.49590  11.48459  43.13552  1.000 28.59935  ? 176 THR A O      1 
ATOM   1102 C  CB     . THR A 1  146 ? -3.90564  10.15830  44.23570  1.000 42.26291  ? 176 THR A CB     1 
ATOM   1103 O  OG1    . THR A 1  146 ? -4.00386  10.25764  42.81009  1.000 56.88389  ? 176 THR A OG1    1 
ATOM   1104 C  CG2    . THR A 1  146 ? -4.38443  11.46358  44.83630  1.000 41.56691  ? 176 THR A CG2    1 
ATOM   1105 N  N      . THR A 1  147 ? -1.10207  11.83867  45.32107  1.000 31.46774  ? 177 THR A N      1 
ATOM   1106 C  CA     . THR A 1  147 ? -0.33570  13.05507  45.08638  1.000 22.52468  ? 177 THR A CA     1 
ATOM   1107 C  C      . THR A 1  147 ? 0.88771   13.11177  45.99049  1.000 25.21386  ? 177 THR A C      1 
ATOM   1108 O  O      . THR A 1  147 ? 0.87361   12.60625  47.11443  1.000 28.33785  ? 177 THR A O      1 
ATOM   1109 C  CB     . THR A 1  147 ? -1.18641  14.32920  45.33593  1.000 31.46109  ? 177 THR A CB     1 
ATOM   1110 O  OG1    . THR A 1  147 ? -1.62850  14.32419  46.69949  1.000 37.71878  ? 177 THR A OG1    1 
ATOM   1111 C  CG2    . THR A 1  147 ? -2.38653  14.37088  44.40374  1.000 37.05102  ? 177 THR A CG2    1 
ATOM   1112 N  N      . ARG A 1  148 ? 1.94100   13.76589  45.49291  1.000 29.07814  ? 178 ARG A N      1 
ATOM   1113 C  CA     . ARG A 1  148 ? 3.17616   13.96506  46.26064  1.000 26.08893  ? 178 ARG A CA     1 
ATOM   1114 C  C      . ARG A 1  148 ? 3.63890   12.65540  46.90443  1.000 20.26967  ? 178 ARG A C      1 
ATOM   1115 O  O      . ARG A 1  148 ? 4.03481   12.60563  48.07773  1.000 22.88134  ? 178 ARG A O      1 
ATOM   1116 C  CB     . ARG A 1  148 ? 2.97135   15.06018  47.30565  1.000 29.91860  ? 178 ARG A CB     1 
ATOM   1117 C  CG     . ARG A 1  148 ? 2.66463   16.40492  46.65546  1.000 33.15006  ? 178 ARG A CG     1 
ATOM   1118 C  CD     . ARG A 1  148 ? 2.34909   17.48984  47.67019  1.000 38.48455  ? 178 ARG A CD     1 
ATOM   1119 N  NE     . ARG A 1  148 ? 3.40505   17.66094  48.66381  1.000 37.47153  ? 178 ARG A NE     1 
ATOM   1120 C  CZ     . ARG A 1  148 ? 4.45332   18.46011  48.50761  1.000 36.17822  ? 178 ARG A CZ     1 
ATOM   1121 N  NH1    . ARG A 1  148 ? 4.69591   19.06366  47.35615  1.000 34.61716  ? 178 ARG A NH1    1 
ATOM   1122 N  NH2    . ARG A 1  148 ? 5.29189   18.63865  49.52482  1.000 25.27644  ? 178 ARG A NH2    1 
ATOM   1123 N  N      . PHE A 1  149 ? 3.58370   11.57614  46.11967  1.000 21.90088  ? 179 PHE A N      1 
ATOM   1124 C  CA     . PHE A 1  149 ? 3.90748   10.22547  46.58060  1.000 23.31363  ? 179 PHE A CA     1 
ATOM   1125 C  C      . PHE A 1  149 ? 5.19194   9.74995   45.91714  1.000 18.05286  ? 179 PHE A C      1 
ATOM   1126 O  O      . PHE A 1  149 ? 5.33968   9.90270   44.70456  1.000 19.74007  ? 179 PHE A O      1 
ATOM   1127 C  CB     . PHE A 1  149 ? 2.76984   9.25733   46.23787  1.000 21.84167  ? 179 PHE A CB     1 
ATOM   1128 C  CG     . PHE A 1  149 ? 3.04551   7.83274   46.61268  1.000 22.69386  ? 179 PHE A CG     1 
ATOM   1129 C  CD1    . PHE A 1  149 ? 3.13708   7.45208   47.94015  1.000 24.94753  ? 179 PHE A CD1    1 
ATOM   1130 C  CD2    . PHE A 1  149 ? 3.22341   6.87245   45.62645  1.000 24.15294  ? 179 PHE A CD2    1 
ATOM   1131 C  CE1    . PHE A 1  149 ? 3.38182   6.13600   48.28453  1.000 26.23219  ? 179 PHE A CE1    1 
ATOM   1132 C  CE2    . PHE A 1  149 ? 3.46600   5.55267   45.96155  1.000 23.72426  ? 179 PHE A CE2    1 
ATOM   1133 C  CZ     . PHE A 1  149 ? 3.55026   5.18417   47.29774  1.000 24.13535  ? 179 PHE A CZ     1 
ATOM   1134 N  N      . PHE A 1  150 ? 6.10939   9.18485   46.71290  1.000 19.79413  ? 180 PHE A N      1 
ATOM   1135 C  CA     . PHE A 1  150 ? 7.38891   8.71135   46.18164  1.000 22.39771  ? 180 PHE A CA     1 
ATOM   1136 C  C      . PHE A 1  150 ? 7.84382   7.53334   47.01785  1.000 18.38478  ? 180 PHE A C      1 
ATOM   1137 O  O      . PHE A 1  150 ? 7.94409   7.63994   48.24836  1.000 19.85767  ? 180 PHE A O      1 
ATOM   1138 C  CB     . PHE A 1  150 ? 8.45035   9.82732   46.19258  1.000 22.73492  ? 180 PHE A CB     1 
ATOM   1139 C  CG     . PHE A 1  150 ? 9.64127   9.57225   45.28237  1.000 16.40512  ? 180 PHE A CG     1 
ATOM   1140 C  CD1    . PHE A 1  150 ? 10.69024  8.74278   45.67602  1.000 22.64282  ? 180 PHE A CD1    1 
ATOM   1141 C  CD2    . PHE A 1  150 ? 9.70444   10.18630  44.03949  1.000 19.29279  ? 180 PHE A CD2    1 
ATOM   1142 C  CE1    . PHE A 1  150 ? 11.79607  8.53307   44.83665  1.000 18.80862  ? 180 PHE A CE1    1 
ATOM   1143 C  CE2    . PHE A 1  150 ? 10.79422  9.97471   43.18565  1.000 22.03611  ? 180 PHE A CE2    1 
ATOM   1144 C  CZ     . PHE A 1  150 ? 11.84311  9.16188   43.58869  1.000 19.25757  ? 180 PHE A CZ     1 
ATOM   1145 N  N      . THR A 1  151 ? 8.13181   6.41229   46.36112  1.000 18.57583  ? 181 THR A N      1 
ATOM   1146 C  CA     . THR A 1  151 ? 8.49396   5.22316   47.10537  1.000 20.47032  ? 181 THR A CA     1 
ATOM   1147 C  C      . THR A 1  151 ? 9.53598   4.40469   46.34166  1.000 17.25658  ? 181 THR A C      1 
ATOM   1148 O  O      . THR A 1  151 ? 9.88566   4.69350   45.19972  1.000 16.75329  ? 181 THR A O      1 
ATOM   1149 C  CB     . THR A 1  151 ? 7.25021   4.36314   47.40800  1.000 20.32190  ? 181 THR A CB     1 
ATOM   1150 O  OG1    . THR A 1  151 ? 7.61161   3.32680   48.34206  1.000 22.60657  ? 181 THR A OG1    1 
ATOM   1151 C  CG2    . THR A 1  151 ? 6.70433   3.76442   46.15090  1.000 21.53258  ? 181 THR A CG2    1 
ATOM   1152 N  N      . GLY A 1  152 ? 10.03823  3.38503   47.00096  1.000 20.27647  ? 182 GLY A N      1 
ATOM   1153 C  CA     . GLY A 1  152 ? 11.03502  2.50888   46.39367  1.000 18.31679  ? 182 GLY A CA     1 
ATOM   1154 C  C      . GLY A 1  152 ? 11.81224  1.82923   47.49868  1.000 19.56202  ? 182 GLY A C      1 
ATOM   1155 O  O      . GLY A 1  152 ? 11.25929  1.51191   48.54437  1.000 21.40235  ? 182 GLY A O      1 
ATOM   1156 N  N      . PHE A 1  153 ? 13.10690  1.59052   47.24785  1.000 17.40405  ? 183 PHE A N      1 
ATOM   1157 C  CA     . PHE A 1  153 ? 13.99720  1.14973   48.30959  1.000 18.99850  ? 183 PHE A CA     1 
ATOM   1158 C  C      . PHE A 1  153 ? 14.55043  2.40578   48.96666  1.000 20.94857  ? 183 PHE A C      1 
ATOM   1159 O  O      . PHE A 1  153 ? 15.35763  3.10964   48.36032  1.000 17.48759  ? 183 PHE A O      1 
ATOM   1160 C  CB     . PHE A 1  153 ? 15.14199  0.26830   47.78717  1.000 16.69378  ? 183 PHE A CB     1 
ATOM   1161 C  CG     . PHE A 1  153 ? 16.05701  -0.19881  48.88914  1.000 20.46817  ? 183 PHE A CG     1 
ATOM   1162 C  CD1    . PHE A 1  153 ? 15.71844  -1.29449  49.66622  1.000 19.78031  ? 183 PHE A CD1    1 
ATOM   1163 C  CD2    . PHE A 1  153 ? 17.23311  0.47397   49.15917  1.000 20.63185  ? 183 PHE A CD2    1 
ATOM   1164 C  CE1    . PHE A 1  153 ? 16.55442  -1.72413  50.70094  1.000 25.62021  ? 183 PHE A CE1    1 
ATOM   1165 C  CE2    . PHE A 1  153 ? 18.07340  0.06323   50.18673  1.000 23.55365  ? 183 PHE A CE2    1 
ATOM   1166 C  CZ     . PHE A 1  153 ? 17.73629  -1.04122  50.95560  1.000 24.64608  ? 183 PHE A CZ     1 
ATOM   1167 N  N      . LEU A 1  154 ? 14.10208  2.70441   50.18094  1.000 18.43296  ? 184 LEU A N      1 
ATOM   1168 C  CA     . LEU A 1  154 ? 14.50099  3.95736   50.83242  1.000 18.98835  ? 184 LEU A CA     1 
ATOM   1169 C  C      . LEU A 1  154 ? 15.93844  3.89137   51.33048  1.000 22.65553  ? 184 LEU A C      1 
ATOM   1170 O  O      . LEU A 1  154 ? 16.33957  2.90953   51.96215  1.000 22.66887  ? 184 LEU A O      1 
ATOM   1171 C  CB     . LEU A 1  154 ? 13.56960  4.28669   51.99961  1.000 23.24580  ? 184 LEU A CB     1 
ATOM   1172 C  CG     . LEU A 1  154 ? 12.26858  4.98948   51.62623  1.000 28.24769  ? 184 LEU A CG     1 
ATOM   1173 C  CD1    . LEU A 1  154 ? 11.43595  4.08003   50.74342  1.000 26.45996  ? 184 LEU A CD1    1 
ATOM   1174 C  CD2    . LEU A 1  154 ? 11.51214  5.43457   52.88377  1.000 27.30554  ? 184 LEU A CD2    1 
ATOM   1175 N  N      . LYS A 1  155 ? 16.69820  4.96069   51.07307  1.000 21.14661  ? 185 LYS A N      1 
ATOM   1176 C  CA     . LYS A 1  155 ? 18.09664  5.07955   51.49395  1.000 23.29036  ? 185 LYS A CA     1 
ATOM   1177 C  C      . LYS A 1  155 ? 18.18977  6.37997   52.29220  1.000 25.52972  ? 185 LYS A C      1 
ATOM   1178 O  O      . LYS A 1  155 ? 18.29836  7.46867   51.71429  1.000 19.16502  ? 185 LYS A O      1 
ATOM   1179 C  CB     . LYS A 1  155 ? 19.03462  5.08482   50.29026  1.000 17.08150  ? 185 LYS A CB     1 
ATOM   1180 C  CG     . LYS A 1  155 ? 18.90777  3.83401   49.41158  1.000 17.99879  ? 185 LYS A CG     1 
ATOM   1181 C  CD     . LYS A 1  155 ? 19.67229  3.96614   48.10031  1.000 21.55372  ? 185 LYS A CD     1 
ATOM   1182 C  CE     . LYS A 1  155 ? 21.20600  3.84810   48.27695  1.000 18.83918  ? 185 LYS A CE     1 
ATOM   1183 N  NZ     . LYS A 1  155 ? 21.62704  2.55379   48.90956  1.000 21.44412  ? 185 LYS A NZ     1 
ATOM   1184 N  N      . LEU A 1  156 ? 18.11812  6.26490   53.61660  1.000 25.39323  ? 186 LEU A N      1 
ATOM   1185 C  CA     . LEU A 1  156 ? 17.88219  7.42486   54.46852  1.000 27.62288  ? 186 LEU A CA     1 
ATOM   1186 C  C      . LEU A 1  156 ? 19.11641  7.93023   55.19152  1.000 34.39804  ? 186 LEU A C      1 
ATOM   1187 O  O      . LEU A 1  156 ? 19.09905  9.06369   55.68549  1.000 41.71149  ? 186 LEU A O      1 
ATOM   1188 C  CB     . LEU A 1  156 ? 16.80521  7.10285   55.50846  1.000 29.67448  ? 186 LEU A CB     1 
ATOM   1189 C  CG     . LEU A 1  156 ? 15.48760  6.63435   54.90746  1.000 31.40771  ? 186 LEU A CG     1 
ATOM   1190 C  CD1    . LEU A 1  156 ? 14.48259  6.34821   56.00908  1.000 31.57395  ? 186 LEU A CD1    1 
ATOM   1191 C  CD2    . LEU A 1  156 ? 14.94345  7.64955   53.91267  1.000 26.88112  ? 186 LEU A CD2    1 
ATOM   1192 N  N      . ASN A 1  157 ? 20.16971  7.12870   55.30067  1.000 29.90668  ? 187 ASN A N      1 
ATOM   1193 C  CA     . ASN A 1  157 ? 21.37950  7.56833   55.99562  1.000 50.10197  ? 187 ASN A CA     1 
ATOM   1194 C  C      . ASN A 1  157 ? 22.60116  7.29470   55.11590  1.000 41.26721  ? 187 ASN A C      1 
ATOM   1195 O  O      . ASN A 1  157 ? 23.47100  6.50021   55.46291  1.000 52.24293  ? 187 ASN A O      1 
ATOM   1196 C  CB     . ASN A 1  157 ? 21.47566  6.87339   57.35727  1.000 55.62211  ? 187 ASN A CB     1 
ATOM   1197 C  CG     . ASN A 1  157 ? 22.53471  7.48307   58.26084  1.000 64.62841  ? 187 ASN A CG     1 
ATOM   1198 O  OD1    . ASN A 1  157 ? 22.45550  8.65355   58.63643  1.000 71.47031  ? 187 ASN A OD1    1 
ATOM   1199 N  ND2    . ASN A 1  157 ? 23.52629  6.67537   58.63236  1.000 57.79234  ? 187 ASN A ND2    1 
ATOM   1200 N  N      . GLU A 1  158 ? 22.66298  7.93813   53.95156  1.000 27.79084  ? 188 GLU A N      1 
ATOM   1201 C  CA     . GLU A 1  158 ? 23.70856  7.63447   52.98395  1.000 24.00778  ? 188 GLU A CA     1 
ATOM   1202 C  C      . GLU A 1  158 ? 24.82199  8.66256   53.05373  1.000 28.90566  ? 188 GLU A C      1 
ATOM   1203 O  O      . GLU A 1  158 ? 24.57452  9.86850   53.12141  1.000 24.29021  ? 188 GLU A O      1 
ATOM   1204 C  CB     . GLU A 1  158 ? 23.19205  7.58474   51.53517  1.000 23.60236  ? 188 GLU A CB     1 
ATOM   1205 C  CG     . GLU A 1  158 ? 22.28593  6.41276   51.25273  1.000 24.26092  ? 188 GLU A CG     1 
ATOM   1206 C  CD     . GLU A 1  158 ? 22.99540  5.06853   51.36070  1.000 23.59237  ? 188 GLU A CD     1 
ATOM   1207 O  OE1    . GLU A 1  158 ? 24.16430  4.92834   50.90921  1.000 29.01342  ? 188 GLU A OE1    1 
ATOM   1208 O  OE2    . GLU A 1  158 ? 22.36773  4.15710   51.93670  1.000 29.50829  ? 188 GLU A OE2    1 
ATOM   1209 N  N      . PHE A 1  159 ? 26.03229  8.17723   52.94266  1.000 20.58827  ? 189 PHE A N      1 
ATOM   1210 C  CA     . PHE A 1  159 ? 27.17585  9.05278   52.90443  1.000 23.64781  ? 189 PHE A CA     1 
ATOM   1211 C  C      . PHE A 1  159 ? 27.79848  8.97138   51.51824  1.000 21.53281  ? 189 PHE A C      1 
ATOM   1212 O  O      . PHE A 1  159 ? 27.80108  7.89993   50.91418  1.000 22.43042  ? 189 PHE A O      1 
ATOM   1213 C  CB     . PHE A 1  159 ? 28.18590  8.65651   53.99730  1.000 31.08819  ? 189 PHE A CB     1 
ATOM   1214 C  CG     . PHE A 1  159 ? 27.58685  8.67573   55.38532  1.000 33.93868  ? 189 PHE A CG     1 
ATOM   1215 C  CD1    . PHE A 1  159 ? 27.53842  9.85331   56.12077  1.000 43.71697  ? 189 PHE A CD1    1 
ATOM   1216 C  CD2    . PHE A 1  159 ? 26.99846  7.54260   55.91961  1.000 38.04310  ? 189 PHE A CD2    1 
ATOM   1217 C  CE1    . PHE A 1  159 ? 26.96246  9.88596   57.38075  1.000 45.23492  ? 189 PHE A CE1    1 
ATOM   1218 C  CE2    . PHE A 1  159 ? 26.41136  7.57220   57.18040  1.000 44.71795  ? 189 PHE A CE2    1 
ATOM   1219 C  CZ     . PHE A 1  159 ? 26.39192  8.74430   57.90705  1.000 50.18681  ? 189 PHE A CZ     1 
ATOM   1220 N  N      . PRO A 1  160 ? 28.19550  10.10228  50.93899  1.000 20.80618  ? 190 PRO A N      1 
ATOM   1221 C  CA     . PRO A 1  160 ? 28.83539  10.06864  49.62221  1.000 18.84037  ? 190 PRO A CA     1 
ATOM   1222 C  C      . PRO A 1  160 ? 30.08214  9.19723   49.66776  1.000 27.02214  ? 190 PRO A C      1 
ATOM   1223 O  O      . PRO A 1  160 ? 30.81367  9.17403   50.65793  1.000 24.70334  ? 190 PRO A O      1 
ATOM   1224 C  CB     . PRO A 1  160 ? 29.18628  11.54592  49.34818  1.000 23.19082  ? 190 PRO A CB     1 
ATOM   1225 C  CG     . PRO A 1  160 ? 29.14344  12.19682  50.67144  1.000 28.76967  ? 190 PRO A CG     1 
ATOM   1226 C  CD     . PRO A 1  160 ? 28.10455  11.47105  51.47325  1.000 21.60161  ? 190 PRO A CD     1 
ATOM   1227 N  N      . ILE A 1  161 ? 30.31898  8.49179   48.57777  1.000 21.41015  ? 191 ILE A N      1 
ATOM   1228 C  CA     . ILE A 1  161 ? 31.43864  7.58174   48.47619  1.000 25.87057  ? 191 ILE A CA     1 
ATOM   1229 C  C      . ILE A 1  161 ? 32.63864  8.38588   48.00410  1.000 21.51773  ? 191 ILE A C      1 
ATOM   1230 O  O      . ILE A 1  161 ? 32.60475  9.00340   46.93114  1.000 21.27648  ? 191 ILE A O      1 
ATOM   1231 C  CB     . ILE A 1  161 ? 31.11786  6.43980   47.51465  1.000 23.68389  ? 191 ILE A CB     1 
ATOM   1232 C  CG1    . ILE A 1  161 ? 30.04429  5.53431   48.12996  1.000 27.73290  ? 191 ILE A CG1    1 
ATOM   1233 C  CG2    . ILE A 1  161 ? 32.40701  5.67312   47.18495  1.000 27.62713  ? 191 ILE A CG2    1 
ATOM   1234 C  CD1    . ILE A 1  161 ? 29.43414  4.58916   47.13022  1.000 29.55389  ? 191 ILE A CD1    1 
ATOM   1235 N  N      . ARG A 1  162 ? 33.68575  8.39255   48.81882  1.000 24.96610  ? 192 ARG A N      1 
ATOM   1236 C  CA     . ARG A 1  162 ? 34.89064  9.15157   48.54442  1.000 20.84465  ? 192 ARG A CA     1 
ATOM   1237 C  C      . ARG A 1  162 ? 36.06516  8.26459   48.10799  1.000 31.06385  ? 192 ARG A C      1 
ATOM   1238 O  O      . ARG A 1  162 ? 37.19382  8.75479   48.05443  1.000 26.81603  ? 192 ARG A O      1 
ATOM   1239 C  CB     . ARG A 1  162 ? 35.27088  9.97131   49.78224  1.000 34.11217  ? 192 ARG A CB     1 
ATOM   1240 C  CG     . ARG A 1  162 ? 34.09402  10.77394  50.37876  1.000 27.60816  ? 192 ARG A CG     1 
ATOM   1241 C  CD     . ARG A 1  162 ? 33.57234  11.81881  49.39345  1.000 23.78338  ? 192 ARG A CD     1 
ATOM   1242 N  NE     . ARG A 1  162 ? 32.77492  12.81658  50.09994  1.000 24.60150  ? 192 ARG A NE     1 
ATOM   1243 C  CZ     . ARG A 1  162 ? 32.12661  13.81818  49.51887  1.000 26.55332  ? 192 ARG A CZ     1 
ATOM   1244 N  NH1    . ARG A 1  162 ? 32.14628  13.98655  48.21325  1.000 18.34646  ? 192 ARG A NH1    1 
ATOM   1245 N  NH2    . ARG A 1  162 ? 31.47938  14.69715  50.27936  1.000 21.64065  ? 192 ARG A NH2    1 
ATOM   1246 N  N      . GLN A 1  163 ? 35.83408  6.98024   47.82932  1.000 30.43845  ? 193 GLN A N      1 
ATOM   1247 C  CA     . GLN A 1  163 ? 36.86331  6.07768   47.25750  1.000 36.18399  ? 193 GLN A CA     1 
ATOM   1248 C  C      . GLN A 1  163 ? 37.05092  6.45216   45.79581  1.000 34.62946  ? 193 GLN A C      1 
ATOM   1249 O  O      . GLN A 1  163 ? 36.14773  6.19476   44.98989  1.000 30.51523  ? 193 GLN A O      1 
ATOM   1250 C  CB     . GLN A 1  163 ? 36.46581  4.60559   47.31606  1.000 45.46610  ? 193 GLN A CB     1 
ATOM   1251 C  CG     . GLN A 1  163 ? 36.09922  4.00035   48.63764  1.000 55.78952  ? 193 GLN A CG     1 
ATOM   1252 C  CD     . GLN A 1  163 ? 35.40760  2.64773   48.41311  1.000 73.06584  ? 193 GLN A CD     1 
ATOM   1253 O  OE1    . GLN A 1  163 ? 35.03572  2.31673   47.28762  1.000 63.64512  ? 193 GLN A OE1    1 
ATOM   1254 N  NE2    . GLN A 1  163 ? 35.24205  1.86956   49.46766  1.000 83.22329  ? 193 GLN A NE2    1 
ATOM   1255 N  N      . PRO A 1  164 ? 38.19865  7.00071   45.39586  1.000 27.75989  ? 194 PRO A N      1 
ATOM   1256 C  CA     . PRO A 1  164 ? 38.26904  7.72076   44.10483  1.000 26.48254  ? 194 PRO A CA     1 
ATOM   1257 C  C      . PRO A 1  164 ? 38.08163  6.88727   42.84295  1.000 35.30300  ? 194 PRO A C      1 
ATOM   1258 O  O      . PRO A 1  164 ? 37.78143  7.46314   41.78916  1.000 37.96659  ? 194 PRO A O      1 
ATOM   1259 C  CB     . PRO A 1  164 ? 39.67132  8.36596   44.14753  1.000 31.93970  ? 194 PRO A CB     1 
ATOM   1260 C  CG     . PRO A 1  164 ? 40.42693  7.55791   45.17140  1.000 33.22575  ? 194 PRO A CG     1 
ATOM   1261 C  CD     . PRO A 1  164 ? 39.42393  7.16953   46.19605  1.000 39.44950  ? 194 PRO A CD     1 
ATOM   1262 N  N      . PHE A 1  165 ? 38.28436  5.57981   42.88636  1.000 25.66577  ? 195 PHE A N      1 
ATOM   1263 C  CA     . PHE A 1  165 ? 38.10396  4.71930   41.72409  1.000 31.71065  ? 195 PHE A CA     1 
ATOM   1264 C  C      . PHE A 1  165 ? 36.79681  3.92992   41.76613  1.000 28.21261  ? 195 PHE A C      1 
ATOM   1265 O  O      . PHE A 1  165 ? 36.57836  3.05668   40.91633  1.000 32.27039  ? 195 PHE A O      1 
ATOM   1266 C  CB     . PHE A 1  165 ? 39.34421  3.83531   41.57178  1.000 33.52968  ? 195 PHE A CB     1 
ATOM   1267 C  CG     . PHE A 1  165 ? 40.60438  4.65626   41.57662  1.000 37.35362  ? 195 PHE A CG     1 
ATOM   1268 C  CD1    . PHE A 1  165 ? 40.92870  5.44422   40.48275  1.000 35.11104  ? 195 PHE A CD1    1 
ATOM   1269 C  CD2    . PHE A 1  165 ? 41.39933  4.72528   42.70657  1.000 34.34195  ? 195 PHE A CD2    1 
ATOM   1270 C  CE1    . PHE A 1  165 ? 42.05882  6.24889   40.50193  1.000 37.36596  ? 195 PHE A CE1    1 
ATOM   1271 C  CE2    . PHE A 1  165 ? 42.52350  5.53154   42.72583  1.000 35.13598  ? 195 PHE A CE2    1 
ATOM   1272 C  CZ     . PHE A 1  165 ? 42.85072  6.28507   41.62678  1.000 33.11988  ? 195 PHE A CZ     1 
ATOM   1273 N  N      . SER A 1  166 ? 35.94843  4.20039   42.75779  1.000 32.57856  ? 196 SER A N      1 
ATOM   1274 C  CA     . SER A 1  166 ? 34.63485  3.56949   42.88550  1.000 33.28061  ? 196 SER A CA     1 
ATOM   1275 C  C      . SER A 1  166 ? 33.66846  4.11600   41.83985  1.000 29.83763  ? 196 SER A C      1 
ATOM   1276 O  O      . SER A 1  166 ? 33.70827  5.29562   41.48000  1.000 27.58344  ? 196 SER A O      1 
ATOM   1277 C  CB     . SER A 1  166 ? 34.05604  3.83044   44.28161  1.000 32.56006  ? 196 SER A CB     1 
ATOM   1278 O  OG     . SER A 1  166 ? 32.62759  3.68453   44.29338  1.000 38.78412  ? 196 SER A OG     1 
ATOM   1279 N  N      . LYS A 1  167 ? 32.77100  3.24360   41.36475  1.000 32.13386  ? 197 LYS A N      1 
ATOM   1280 C  CA     . LYS A 1  167 ? 31.81844  3.65933   40.33551  1.000 30.79019  ? 197 LYS A CA     1 
ATOM   1281 C  C      . LYS A 1  167 ? 30.96058  4.84677   40.77556  1.000 27.46592  ? 197 LYS A C      1 
ATOM   1282 O  O      . LYS A 1  167 ? 30.58938  5.69404   39.94627  1.000 26.49590  ? 197 LYS A O      1 
ATOM   1283 C  CB     . LYS A 1  167 ? 30.92565  2.46371   39.99077  1.000 37.62515  ? 197 LYS A CB     1 
ATOM   1284 C  CG     . LYS A 1  167 ? 29.79862  2.73569   39.01827  1.000 44.58940  ? 197 LYS A CG     1 
ATOM   1285 C  CD     . LYS A 1  167 ? 28.88869  1.50944   38.93771  1.000 38.64004  ? 197 LYS A CD     1 
ATOM   1286 C  CE     . LYS A 1  167 ? 27.82645  1.64990   37.86251  1.000 56.37228  ? 197 LYS A CE     1 
ATOM   1287 N  NZ     . LYS A 1  167 ? 28.38994  1.63193   36.47931  1.000 60.33863  ? 197 LYS A NZ     1 
ATOM   1288 N  N      . TRP A 1  168 ? 30.67640  4.95097   42.07040  1.000 24.97791  ? 198 TRP A N      1 
ATOM   1289 C  CA     . TRP A 1  168 ? 29.83681  6.01412   42.60676  1.000 28.41154  ? 198 TRP A CA     1 
ATOM   1290 C  C      . TRP A 1  168 ? 30.63519  7.08605   43.34053  1.000 26.98350  ? 198 TRP A C      1 
ATOM   1291 O  O      . TRP A 1  168 ? 30.08509  7.80698   44.17744  1.000 22.04076  ? 198 TRP A O      1 
ATOM   1292 C  CB     . TRP A 1  168 ? 28.78834  5.40080   43.52436  1.000 30.51669  ? 198 TRP A CB     1 
ATOM   1293 C  CG     . TRP A 1  168 ? 27.87831  4.43613   42.79670  1.000 30.24373  ? 198 TRP A CG     1 
ATOM   1294 C  CD1    . TRP A 1  168 ? 27.21996  4.64468   41.60445  1.000 33.31705  ? 198 TRP A CD1    1 
ATOM   1295 C  CD2    . TRP A 1  168 ? 27.55814  3.12170   43.21088  1.000 29.91419  ? 198 TRP A CD2    1 
ATOM   1296 N  NE1    . TRP A 1  168 ? 26.48724  3.51993   41.26907  1.000 35.52227  ? 198 TRP A NE1    1 
ATOM   1297 C  CE2    . TRP A 1  168 ? 26.68297  2.57031   42.23932  1.000 35.96138  ? 198 TRP A CE2    1 
ATOM   1298 C  CE3    . TRP A 1  168 ? 27.91442  2.34499   44.31887  1.000 35.53518  ? 198 TRP A CE3    1 
ATOM   1299 C  CZ2    . TRP A 1  168 ? 26.16582  1.28028   42.35188  1.000 41.30866  ? 198 TRP A CZ2    1 
ATOM   1300 C  CZ3    . TRP A 1  168 ? 27.39405  1.06962   44.42735  1.000 40.39203  ? 198 TRP A CZ3    1 
ATOM   1301 C  CH2    . TRP A 1  168 ? 26.53059  0.54757   43.45036  1.000 45.72353  ? 198 TRP A CH2    1 
ATOM   1302 N  N      . PHE A 1  169 ? 31.93263  7.18452   43.06351  1.000 20.63317  ? 199 PHE A N      1 
ATOM   1303 C  CA     . PHE A 1  169 ? 32.73601  8.22630   43.67130  1.000 20.16386  ? 199 PHE A CA     1 
ATOM   1304 C  C      . PHE A 1  169 ? 32.22415  9.61766   43.30480  1.000 13.82095  ? 199 PHE A C      1 
ATOM   1305 O  O      . PHE A 1  169 ? 31.92771  9.90293   42.14940  1.000 19.92763  ? 199 PHE A O      1 
ATOM   1306 C  CB     . PHE A 1  169 ? 34.19615  8.07838   43.23299  1.000 23.71326  ? 199 PHE A CB     1 
ATOM   1307 C  CG     . PHE A 1  169 ? 35.04975  9.27856   43.56475  1.000 22.27856  ? 199 PHE A CG     1 
ATOM   1308 C  CD1    . PHE A 1  169 ? 35.39432  9.53562   44.87405  1.000 24.69575  ? 199 PHE A CD1    1 
ATOM   1309 C  CD2    . PHE A 1  169 ? 35.51971  10.11707  42.56966  1.000 27.25279  ? 199 PHE A CD2    1 
ATOM   1310 C  CE1    . PHE A 1  169 ? 36.20039  10.64139  45.20782  1.000 27.00479  ? 199 PHE A CE1    1 
ATOM   1311 C  CE2    . PHE A 1  169 ? 36.33015  11.22085  42.89099  1.000 21.62248  ? 199 PHE A CE2    1 
ATOM   1312 C  CZ     . PHE A 1  169 ? 36.65573  11.47132  44.20600  1.000 25.91023  ? 199 PHE A CZ     1 
ATOM   1313 N  N      . VAL A 1  170 ? 32.16288  10.49574  44.30410  1.000 18.19029  ? 200 VAL A N      1 
ATOM   1314 C  CA     . VAL A 1  170 ? 31.92708  11.91885  44.08431  1.000 20.44363  ? 200 VAL A CA     1 
ATOM   1315 C  C      . VAL A 1  170 ? 32.96402  12.68932  44.87438  1.000 18.29324  ? 200 VAL A C      1 
ATOM   1316 O  O      . VAL A 1  170 ? 33.13756  12.45257  46.07696  1.000 21.57552  ? 200 VAL A O      1 
ATOM   1317 C  CB     . VAL A 1  170 ? 30.49405  12.35745  44.47352  1.000 22.65669  ? 200 VAL A CB     1 
ATOM   1318 C  CG1    . VAL A 1  170 ? 29.47848  11.66931  43.57013  1.000 24.90080  ? 200 VAL A CG1    1 
ATOM   1319 C  CG2    . VAL A 1  170 ? 30.22586  12.06422  45.93423  1.000 21.67285  ? 200 VAL A CG2    1 
ATOM   1320 N  N      . SER A 1  171 ? 33.66980  13.58940  44.18924  1.000 24.83610  ? 201 SER A N      1 
ATOM   1321 C  CA     . SER A 1  171 ? 34.62234  14.46808  44.84411  1.000 27.84570  ? 201 SER A CA     1 
ATOM   1322 C  C      . SER A 1  171 ? 33.88822  15.45073  45.74532  1.000 25.31719  ? 201 SER A C      1 
ATOM   1323 O  O      . SER A 1  171 ? 32.66750  15.61859  45.66236  1.000 22.22839  ? 201 SER A O      1 
ATOM   1324 C  CB     . SER A 1  171 ? 35.45287  15.23268  43.81600  1.000 28.56565  ? 201 SER A CB     1 
ATOM   1325 O  OG     . SER A 1  171 ? 34.69785  16.28953  43.23039  1.000 25.97213  ? 201 SER A OG     1 
ATOM   1326 N  N      . LYS A 1  172 ? 34.65121  16.12109  46.61121  1.000 22.16048  ? 202 LYS A N      1 
ATOM   1327 C  CA     . LYS A 1  172 ? 34.03739  17.13028  47.46235  1.000 24.41100  ? 202 LYS A CA     1 
ATOM   1328 C  C      . LYS A 1  172 ? 33.54778  18.31836  46.64323  1.000 23.51252  ? 202 LYS A C      1 
ATOM   1329 O  O      . LYS A 1  172 ? 32.54675  18.94022  47.00291  1.000 30.08226  ? 202 LYS A O      1 
ATOM   1330 C  CB     . LYS A 1  172 ? 35.02954  17.57187  48.54907  1.000 24.86916  ? 202 LYS A CB     1 
ATOM   1331 C  CG     . LYS A 1  172 ? 35.38674  16.41128  49.48848  1.000 31.37789  ? 202 LYS A CG     1 
ATOM   1332 C  CD     . LYS A 1  172 ? 35.32488  16.80239  50.96095  1.000 41.50051  ? 202 LYS A CD     1 
ATOM   1333 C  CE     . LYS A 1  172 ? 35.87312  15.67489  51.82654  1.000 37.97908  ? 202 LYS A CE     1 
ATOM   1334 N  NZ     . LYS A 1  172 ? 35.67055  14.36369  51.14422  1.000 46.20650  ? 202 LYS A NZ     1 
ATOM   1335 N  N      . SER A 1  173 ? 34.19699  18.63076  45.51927  1.000 21.98397  ? 203 SER A N      1 
ATOM   1336 C  CA     A SER A 1  173 ? 33.67630  19.70182  44.67104  0.560 25.36811  ? 203 SER A CA     1 
ATOM   1337 C  CA     B SER A 1  173 ? 33.67573  19.69898  44.67118  0.440 25.37933  ? 203 SER A CA     1 
ATOM   1338 C  C      . SER A 1  173 ? 32.38199  19.28960  43.98283  1.000 24.68830  ? 203 SER A C      1 
ATOM   1339 O  O      . SER A 1  173 ? 31.51575  20.13583  43.74759  1.000 25.56390  ? 203 SER A O      1 
ATOM   1340 C  CB     A SER A 1  173 ? 34.71495  20.12228  43.63038  0.560 29.55772  ? 203 SER A CB     1 
ATOM   1341 C  CB     B SER A 1  173 ? 34.72071  20.10639  43.63994  0.440 29.54680  ? 203 SER A CB     1 
ATOM   1342 O  OG     A SER A 1  173 ? 34.76103  19.22022  42.54406  0.560 28.24565  ? 203 SER A OG     1 
ATOM   1343 O  OG     B SER A 1  173 ? 35.85709  20.63152  44.29794  0.440 28.40516  ? 203 SER A OG     1 
ATOM   1344 N  N      . GLU A 1  174 ? 32.23279  18.00083  43.66213  1.000 18.86045  ? 204 GLU A N      1 
ATOM   1345 C  CA     . GLU A 1  174 ? 31.00311  17.50646  43.04097  1.000 24.68476  ? 204 GLU A CA     1 
ATOM   1346 C  C      . GLU A 1  174 ? 29.85844  17.45511  44.04111  1.000 23.71990  ? 204 GLU A C      1 
ATOM   1347 O  O      . GLU A 1  174 ? 28.71743  17.79716  43.70077  1.000 25.64243  ? 204 GLU A O      1 
ATOM   1348 C  CB     . GLU A 1  174 ? 31.22798  16.11463  42.44227  1.000 24.19466  ? 204 GLU A CB     1 
ATOM   1349 C  CG     . GLU A 1  174 ? 32.04089  16.11857  41.15841  1.000 24.74336  ? 204 GLU A CG     1 
ATOM   1350 C  CD     . GLU A 1  174 ? 32.44504  14.71390  40.69978  1.000 31.77726  ? 204 GLU A CD     1 
ATOM   1351 O  OE1    . GLU A 1  174 ? 32.82424  13.88867  41.55688  1.000 28.13269  ? 204 GLU A OE1    1 
ATOM   1352 O  OE2    . GLU A 1  174 ? 32.39470  14.45205  39.48247  1.000 31.67481  ? 204 GLU A OE2    1 
ATOM   1353 N  N      . TYR A 1  175 ? 30.13662  17.00563  45.26890  1.000 20.57663  ? 205 TYR A N      1 
ATOM   1354 C  CA     . TYR A 1  175 ? 29.16194  17.00936  46.35538  1.000 20.53613  ? 205 TYR A CA     1 
ATOM   1355 C  C      . TYR A 1  175 ? 29.89612  17.26880  47.66328  1.000 20.81064  ? 205 TYR A C      1 
ATOM   1356 O  O      . TYR A 1  175 ? 30.56841  16.37805  48.21302  1.000 21.30582  ? 205 TYR A O      1 
ATOM   1357 C  CB     . TYR A 1  175 ? 28.37441  15.68600  46.42954  1.000 17.22644  ? 205 TYR A CB     1 
ATOM   1358 C  CG     . TYR A 1  175 ? 27.25505  15.78269  47.42634  1.000 21.24078  ? 205 TYR A CG     1 
ATOM   1359 C  CD1    . TYR A 1  175 ? 26.03879  16.35571  47.07372  1.000 18.81819  ? 205 TYR A CD1    1 
ATOM   1360 C  CD2    . TYR A 1  175 ? 27.43608  15.37068  48.74859  1.000 15.74904  ? 205 TYR A CD2    1 
ATOM   1361 C  CE1    . TYR A 1  175 ? 24.99658  16.45901  48.00416  1.000 21.83238  ? 205 TYR A CE1    1 
ATOM   1362 C  CE2    . TYR A 1  175 ? 26.40073  15.47562  49.68271  1.000 20.25498  ? 205 TYR A CE2    1 
ATOM   1363 C  CZ     . TYR A 1  175 ? 25.18637  16.02987  49.29756  1.000 18.77174  ? 205 TYR A CZ     1 
ATOM   1364 O  OH     . TYR A 1  175 ? 24.14712  16.12903  50.19481  1.000 19.59051  ? 205 TYR A OH     1 
ATOM   1365 N  N      . PRO A 1  176 ? 29.76495  18.47596  48.20359  1.000 19.08315  ? 206 PRO A N      1 
ATOM   1366 C  CA     . PRO A 1  176 ? 30.63377  18.92224  49.29812  1.000 19.49371  ? 206 PRO A CA     1 
ATOM   1367 C  C      . PRO A 1  176 ? 30.18051  18.61515  50.71650  1.000 26.37260  ? 206 PRO A C      1 
ATOM   1368 O  O      . PRO A 1  176 ? 30.90301  18.97751  51.65293  1.000 28.03368  ? 206 PRO A O      1 
ATOM   1369 C  CB     . PRO A 1  176 ? 30.68118  20.44348  49.06569  1.000 22.18365  ? 206 PRO A CB     1 
ATOM   1370 C  CG     . PRO A 1  176 ? 29.34917  20.76194  48.50022  1.000 17.52292  ? 206 PRO A CG     1 
ATOM   1371 C  CD     . PRO A 1  176 ? 28.99777  19.58276  47.59445  1.000 19.25628  ? 206 PRO A CD     1 
ATOM   1372 N  N      . TRP A 1  177 ? 29.02880  17.98714  50.93323  1.000 20.29252  ? 207 TRP A N      1 
ATOM   1373 C  CA     . TRP A 1  177 ? 28.53625  17.79881  52.28714  1.000 19.58942  ? 207 TRP A CA     1 
ATOM   1374 C  C      . TRP A 1  177 ? 28.70942  16.34605  52.72061  1.000 19.91299  ? 207 TRP A C      1 
ATOM   1375 O  O      . TRP A 1  177 ? 28.98739  15.45404  51.90329  1.000 22.14303  ? 207 TRP A O      1 
ATOM   1376 C  CB     . TRP A 1  177 ? 27.07420  18.26111  52.39011  1.000 16.54668  ? 207 TRP A CB     1 
ATOM   1377 C  CG     . TRP A 1  177 ? 26.98637  19.75545  52.02997  1.000 15.99084  ? 207 TRP A CG     1 
ATOM   1378 C  CD1    . TRP A 1  177 ? 27.45481  20.80740  52.77759  1.000 17.70616  ? 207 TRP A CD1    1 
ATOM   1379 C  CD2    . TRP A 1  177 ? 26.41153  20.32670  50.84795  1.000 21.02761  ? 207 TRP A CD2    1 
ATOM   1380 N  NE1    . TRP A 1  177 ? 27.21014  22.00074  52.12143  1.000 20.46833  ? 207 TRP A NE1    1 
ATOM   1381 C  CE2    . TRP A 1  177 ? 26.58050  21.72771  50.93248  1.000 17.06597  ? 207 TRP A CE2    1 
ATOM   1382 C  CE3    . TRP A 1  177 ? 25.78516  19.78902  49.71929  1.000 22.83913  ? 207 TRP A CE3    1 
ATOM   1383 C  CZ2    . TRP A 1  177 ? 26.10650  22.60193  49.95054  1.000 18.14044  ? 207 TRP A CZ2    1 
ATOM   1384 C  CZ3    . TRP A 1  177 ? 25.33955  20.66360  48.72687  1.000 23.57097  ? 207 TRP A CZ3    1 
ATOM   1385 C  CH2    . TRP A 1  177 ? 25.49814  22.04662  48.85597  1.000 18.93134  ? 207 TRP A CH2    1 
ATOM   1386 N  N      . ASP A 1  178 ? 28.56323  16.13241  54.03777  1.000 20.54246  ? 208 ASP A N      1 
ATOM   1387 C  CA     . ASP A 1  178 ? 28.91930  14.83080  54.63258  1.000 22.26624  ? 208 ASP A CA     1 
ATOM   1388 C  C      . ASP A 1  178 ? 27.90319  13.74223  54.33244  1.000 23.30513  ? 208 ASP A C      1 
ATOM   1389 O  O      . ASP A 1  178 ? 28.24884  12.55396  54.37087  1.000 21.24235  ? 208 ASP A O      1 
ATOM   1390 C  CB     . ASP A 1  178 ? 29.01740  14.92653  56.15441  1.000 24.18133  ? 208 ASP A CB     1 
ATOM   1391 C  CG     . ASP A 1  178 ? 30.19221  15.75639  56.65331  1.000 26.97862  ? 208 ASP A CG     1 
ATOM   1392 O  OD1    . ASP A 1  178 ? 31.08813  16.17549  55.87813  1.000 24.82366  ? 208 ASP A OD1    1 
ATOM   1393 O  OD2    . ASP A 1  178 ? 30.21978  15.92699  57.88957  1.000 27.81399  ? 208 ASP A OD2    1 
ATOM   1394 N  N      . ARG A 1  179 ? 26.63943  14.11012  54.11816  1.000 20.60494  ? 209 ARG A N      1 
ATOM   1395 C  CA     . ARG A 1  179 ? 25.56868  13.14837  53.92208  1.000 19.69334  ? 209 ARG A CA     1 
ATOM   1396 C  C      . ARG A 1  179 ? 24.72628  13.55013  52.72397  1.000 19.69745  ? 209 ARG A C      1 
ATOM   1397 O  O      . ARG A 1  179 ? 24.65187  14.72367  52.37066  1.000 19.85781  ? 209 ARG A O      1 
ATOM   1398 C  CB     . ARG A 1  179 ? 24.61143  13.00856  55.10494  1.000 29.53679  ? 209 ARG A CB     1 
ATOM   1399 C  CG     . ARG A 1  179 ? 25.21976  12.39549  56.32621  1.000 39.00125  ? 209 ARG A CG     1 
ATOM   1400 C  CD     . ARG A 1  179 ? 24.16816  11.86066  57.29757  1.000 50.27006  ? 209 ARG A CD     1 
ATOM   1401 N  NE     . ARG A 1  179 ? 23.33463  12.87344  57.92257  1.000 56.78986  ? 209 ARG A NE     1 
ATOM   1402 C  CZ     . ARG A 1  179 ? 23.79446  13.70898  58.83724  1.000 60.11692  ? 209 ARG A CZ     1 
ATOM   1403 N  NH1    . ARG A 1  179 ? 25.07908  13.81400  59.06345  1.000 65.71692  ? 209 ARG A NH1    1 
ATOM   1404 N  NH2    . ARG A 1  179 ? 22.94713  14.46442  59.52636  1.000 60.72692  ? 209 ARG A NH2    1 
ATOM   1405 N  N      . TYR A 1  180 ? 24.08013  12.54351  52.10965  1.000 19.50212  ? 210 TYR A N      1 
ATOM   1406 C  CA     . TYR A 1  180 ? 23.11629  12.76297  51.04504  1.000 16.34142  ? 210 TYR A CA     1 
ATOM   1407 C  C      . TYR A 1  180 ? 21.75035  13.02060  51.65417  1.000 19.94128  ? 210 TYR A C      1 
ATOM   1408 O  O      . TYR A 1  180 ? 21.48158  12.62445  52.79513  1.000 20.59635  ? 210 TYR A O      1 
ATOM   1409 C  CB     . TYR A 1  180 ? 23.02728  11.51241  50.15538  1.000 19.43178  ? 210 TYR A CB     1 
ATOM   1410 C  CG     . TYR A 1  180 ? 24.14704  11.33340  49.15417  1.000 20.48565  ? 210 TYR A CG     1 
ATOM   1411 C  CD1    . TYR A 1  180 ? 24.72425  12.42314  48.51015  1.000 20.82894  ? 210 TYR A CD1    1 
ATOM   1412 C  CD2    . TYR A 1  180 ? 24.64962  10.05914  48.87394  1.000 20.89696  ? 210 TYR A CD2    1 
ATOM   1413 C  CE1    . TYR A 1  180 ? 25.75774  12.25612  47.59095  1.000 19.72226  ? 210 TYR A CE1    1 
ATOM   1414 C  CE2    . TYR A 1  180 ? 25.68470  9.88345   47.95595  1.000 22.06269  ? 210 TYR A CE2    1 
ATOM   1415 C  CZ     . TYR A 1  180 ? 26.23177  10.98002  47.31825  1.000 18.74023  ? 210 TYR A CZ     1 
ATOM   1416 O  OH     . TYR A 1  180 ? 27.25180  10.83103  46.39190  1.000 18.72870  ? 210 TYR A OH     1 
ATOM   1417 N  N      . PRO A 1  181 ? 20.86219  13.65998  50.91037  1.000 16.24405  ? 211 PRO A N      1 
ATOM   1418 C  CA     . PRO A 1  181 ? 19.45851  13.74540  51.32914  1.000 16.67228  ? 211 PRO A CA     1 
ATOM   1419 C  C      . PRO A 1  181 ? 18.84546  12.35865  51.33842  1.000 18.54553  ? 211 PRO A C      1 
ATOM   1420 O  O      . PRO A 1  181 ? 19.46448  11.40881  50.82558  1.000 19.79837  ? 211 PRO A O      1 
ATOM   1421 C  CB     . PRO A 1  181 ? 18.82765  14.59132  50.21726  1.000 16.56412  ? 211 PRO A CB     1 
ATOM   1422 C  CG     . PRO A 1  181 ? 19.61373  14.20183  48.99654  1.000 18.52638  ? 211 PRO A CG     1 
ATOM   1423 C  CD     . PRO A 1  181 ? 21.05466  14.07520  49.50957  1.000 14.38178  ? 211 PRO A CD     1 
ATOM   1424 N  N      . PRO A 1  182 ? 17.62673  12.19949  51.86023  1.000 23.70564  ? 212 PRO A N      1 
ATOM   1425 C  CA     . PRO A 1  182 ? 16.92942  10.91918  51.66587  1.000 22.23095  ? 212 PRO A CA     1 
ATOM   1426 C  C      . PRO A 1  182 ? 16.70865  10.70734  50.17898  1.000 16.29297  ? 212 PRO A C      1 
ATOM   1427 O  O      . PRO A 1  182 ? 16.36816  11.63835  49.45002  1.000 16.81974  ? 212 PRO A O      1 
ATOM   1428 C  CB     . PRO A 1  182 ? 15.59863  11.10255  52.41709  1.000 24.58538  ? 212 PRO A CB     1 
ATOM   1429 C  CG     . PRO A 1  182 ? 15.77418  12.34969  53.26979  1.000 26.59664  ? 212 PRO A CG     1 
ATOM   1430 C  CD     . PRO A 1  182 ? 16.77380  13.20369  52.53985  1.000 23.48957  ? 212 PRO A CD     1 
ATOM   1431 N  N      . PHE A 1  183 ? 16.89512  9.46678   49.71200  1.000 17.41747  ? 213 PHE A N      1 
ATOM   1432 C  CA     . PHE A 1  183 ? 16.54302  9.19306   48.32501  1.000 18.28487  ? 213 PHE A CA     1 
ATOM   1433 C  C      . PHE A 1  183 ? 16.21666  7.70699   48.20482  1.000 16.42274  ? 213 PHE A C      1 
ATOM   1434 O  O      . PHE A 1  183 ? 16.36242  6.95488   49.16059  1.000 17.23260  ? 213 PHE A O      1 
ATOM   1435 C  CB     . PHE A 1  183 ? 17.65516  9.65408   47.37281  1.000 14.10423  ? 213 PHE A CB     1 
ATOM   1436 C  CG     . PHE A 1  183 ? 18.94554  8.85910   47.48319  1.000 16.99990  ? 213 PHE A CG     1 
ATOM   1437 C  CD1    . PHE A 1  183 ? 19.89327  9.16211   48.46661  1.000 15.90694  ? 213 PHE A CD1    1 
ATOM   1438 C  CD2    . PHE A 1  183 ? 19.20564  7.82992   46.58781  1.000 19.64009  ? 213 PHE A CD2    1 
ATOM   1439 C  CE1    . PHE A 1  183 ? 21.09030  8.44215   48.55097  1.000 18.18242  ? 213 PHE A CE1    1 
ATOM   1440 C  CE2    . PHE A 1  183 ? 20.38749  7.08847   46.67435  1.000 21.44838  ? 213 PHE A CE2    1 
ATOM   1441 C  CZ     . PHE A 1  183 ? 21.32073  7.38766   47.65128  1.000 18.92432  ? 213 PHE A CZ     1 
ATOM   1442 N  N      . CYS A 1  184 ? 15.72412  7.30323   47.04191  1.000 15.67993  ? 214 CYS A N      1 
ATOM   1443 C  CA     . CYS A 1  184 ? 15.42731  5.88974   46.78128  1.000 16.35114  ? 214 CYS A CA     1 
ATOM   1444 C  C      . CYS A 1  184 ? 16.36549  5.33894   45.71664  1.000 15.97450  ? 214 CYS A C      1 
ATOM   1445 O  O      . CYS A 1  184 ? 16.73054  6.03944   44.77288  1.000 16.84566  ? 214 CYS A O      1 
ATOM   1446 C  CB     . CYS A 1  184 ? 13.98799  5.67634   46.32370  1.000 17.39237  ? 214 CYS A CB     1 
ATOM   1447 S  SG     . CYS A 1  184 ? 12.73719  6.01388   47.59431  1.000 22.55522  ? 214 CYS A SG     1 
ATOM   1448 N  N      . SER A 1  185 ? 16.70899  4.05550   45.84880  1.000 14.45611  ? 215 SER A N      1 
ATOM   1449 C  CA     . SER A 1  185 ? 17.64334  3.44263   44.90586  1.000 15.83385  ? 215 SER A CA     1 
ATOM   1450 C  C      . SER A 1  185 ? 17.20285  3.68213   43.45936  1.000 19.64897  ? 215 SER A C      1 
ATOM   1451 O  O      . SER A 1  185 ? 16.04313  3.44877   43.10651  1.000 15.86619  ? 215 SER A O      1 
ATOM   1452 C  CB     . SER A 1  185 ? 17.73147  1.93373   45.17998  1.000 15.03908  ? 215 SER A CB     1 
ATOM   1453 O  OG     . SER A 1  185 ? 18.49742  1.29104   44.16787  1.000 16.86603  ? 215 SER A OG     1 
ATOM   1454 N  N      . GLY A 1  186 ? 18.14129  4.11196   42.61405  1.000 14.39951  ? 216 GLY A N      1 
ATOM   1455 C  CA     . GLY A 1  186 ? 17.88537  4.30189   41.20372  1.000 15.37642  ? 216 GLY A CA     1 
ATOM   1456 C  C      . GLY A 1  186 ? 17.54701  3.02905   40.44233  1.000 16.74846  ? 216 GLY A C      1 
ATOM   1457 O  O      . GLY A 1  186 ? 17.09135  3.11843   39.29040  1.000 19.92677  ? 216 GLY A O      1 
ATOM   1458 N  N      . THR A 1  187 ? 17.72584  1.86491   41.05517  1.000 13.99347  ? 217 THR A N      1 
ATOM   1459 C  CA     . THR A 1  187 ? 17.35645  0.63117   40.36600  1.000 12.58861  ? 217 THR A CA     1 
ATOM   1460 C  C      . THR A 1  187 ? 15.87264  0.61009   40.00982  1.000 20.26880  ? 217 THR A C      1 
ATOM   1461 O  O      . THR A 1  187 ? 15.48308  -0.01087  39.00896  1.000 16.23256  ? 217 THR A O      1 
ATOM   1462 C  CB     . THR A 1  187 ? 17.73143  -0.61385  41.19604  1.000 17.77948  ? 217 THR A CB     1 
ATOM   1463 O  OG1    . THR A 1  187 ? 17.12781  -0.55629  42.50074  1.000 18.48488  ? 217 THR A OG1    1 
ATOM   1464 C  CG2    . THR A 1  187 ? 19.26604  -0.74148  41.32394  1.000 19.14040  ? 217 THR A CG2    1 
ATOM   1465 N  N      . GLY A 1  188 ? 15.02960  1.25515   40.81510  1.000 18.27243  ? 218 GLY A N      1 
ATOM   1466 C  CA     . GLY A 1  188 ? 13.60463  1.28330   40.48163  1.000 17.56945  ? 218 GLY A CA     1 
ATOM   1467 C  C      . GLY A 1  188 ? 12.86303  2.03107   41.56601  1.000 14.94370  ? 218 GLY A C      1 
ATOM   1468 O  O      . GLY A 1  188 ? 12.84295  1.57085   42.70852  1.000 17.38448  ? 218 GLY A O      1 
ATOM   1469 N  N      . TYR A 1  189 ? 12.27512  3.19030   41.23479  1.000 18.67784  ? 219 TYR A N      1 
ATOM   1470 C  CA     . TYR A 1  189 ? 11.45665  3.93483   42.19328  1.000 15.12847  ? 219 TYR A CA     1 
ATOM   1471 C  C      . TYR A 1  189 ? 10.16947  4.38203   41.50950  1.000 15.41412  ? 219 TYR A C      1 
ATOM   1472 O  O      . TYR A 1  189 ? 10.07632  4.43670   40.27824  1.000 17.35049  ? 219 TYR A O      1 
ATOM   1473 C  CB     . TYR A 1  189 ? 12.18696  5.14785   42.83017  1.000 18.74833  ? 219 TYR A CB     1 
ATOM   1474 C  CG     . TYR A 1  189 ? 12.88129  6.08518   41.87844  1.000 18.34958  ? 219 TYR A CG     1 
ATOM   1475 C  CD1    . TYR A 1  189 ? 12.17250  7.02094   41.12698  1.000 20.28028  ? 219 TYR A CD1    1 
ATOM   1476 C  CD2    . TYR A 1  189 ? 14.26068  6.04465   41.73462  1.000 20.02980  ? 219 TYR A CD2    1 
ATOM   1477 C  CE1    . TYR A 1  189 ? 12.82479  7.88728   40.24503  1.000 17.53371  ? 219 TYR A CE1    1 
ATOM   1478 C  CE2    . TYR A 1  189 ? 14.91719  6.89894   40.87367  1.000 20.60607  ? 219 TYR A CE2    1 
ATOM   1479 C  CZ     . TYR A 1  189 ? 14.18568  7.82115   40.12399  1.000 20.02985  ? 219 TYR A CZ     1 
ATOM   1480 O  OH     . TYR A 1  189 ? 14.82372  8.65389   39.24514  1.000 16.65769  ? 219 TYR A OH     1 
ATOM   1481 N  N      . VAL A 1  190 ? 9.17167   4.70166   42.33521  1.000 17.08913  ? 220 VAL A N      1 
ATOM   1482 C  CA     . VAL A 1  190 ? 7.81475   4.95448   41.85203  1.000 16.46583  ? 220 VAL A CA     1 
ATOM   1483 C  C      . VAL A 1  190 ? 7.29122   6.24329   42.46676  1.000 15.74819  ? 220 VAL A C      1 
ATOM   1484 O  O      . VAL A 1  190 ? 7.48923   6.49567   43.65875  1.000 18.11064  ? 220 VAL A O      1 
ATOM   1485 C  CB     . VAL A 1  190 ? 6.86649   3.79089   42.19909  1.000 17.43327  ? 220 VAL A CB     1 
ATOM   1486 C  CG1    . VAL A 1  190 ? 5.49814   4.01305   41.55085  1.000 20.27714  ? 220 VAL A CG1    1 
ATOM   1487 C  CG2    . VAL A 1  190 ? 7.47825   2.45092   41.75994  1.000 15.76090  ? 220 VAL A CG2    1 
ATOM   1488 N  N      . PHE A 1  191 ? 6.57682   7.03066   41.66490  1.000 18.58388  ? 221 PHE A N      1 
ATOM   1489 C  CA     . PHE A 1  191 ? 6.02220   8.28044   42.17104  1.000 18.51978  ? 221 PHE A CA     1 
ATOM   1490 C  C      . PHE A 1  191 ? 4.69905   8.60017   41.49143  1.000 21.23373  ? 221 PHE A C      1 
ATOM   1491 O  O      . PHE A 1  191 ? 4.46332   8.21533   40.34481  1.000 20.55336  ? 221 PHE A O      1 
ATOM   1492 C  CB     . PHE A 1  191 ? 6.98696   9.46539   41.97006  1.000 17.12570  ? 221 PHE A CB     1 
ATOM   1493 C  CG     . PHE A 1  191 ? 7.58215   9.56792   40.58351  1.000 21.11615  ? 221 PHE A CG     1 
ATOM   1494 C  CD1    . PHE A 1  191 ? 8.75598   8.87703   40.26403  1.000 21.21372  ? 221 PHE A CD1    1 
ATOM   1495 C  CD2    . PHE A 1  191 ? 7.00778   10.37945  39.61245  1.000 23.37414  ? 221 PHE A CD2    1 
ATOM   1496 C  CE1    . PHE A 1  191 ? 9.32818   8.98281   38.99353  1.000 20.27461  ? 221 PHE A CE1    1 
ATOM   1497 C  CE2    . PHE A 1  191 ? 7.57648   10.49957  38.33795  1.000 25.11717  ? 221 PHE A CE2    1 
ATOM   1498 C  CZ     . PHE A 1  191 ? 8.73077   9.79944   38.02286  1.000 23.71272  ? 221 PHE A CZ     1 
ATOM   1499 N  N      . SER A 1  192 ? 3.84446   9.32880   42.21087  1.000 24.15865  ? 222 SER A N      1 
ATOM   1500 C  CA     . SER A 1  192 ? 2.62294   9.82344   41.58371  1.000 24.99052  ? 222 SER A CA     1 
ATOM   1501 C  C      . SER A 1  192 ? 2.98296   10.81693  40.48767  1.000 25.58779  ? 222 SER A C      1 
ATOM   1502 O  O      . SER A 1  192 ? 3.96618   11.56425  40.58922  1.000 22.04589  ? 222 SER A O      1 
ATOM   1503 C  CB     . SER A 1  192 ? 1.69084   10.46978  42.61446  1.000 28.82137  ? 222 SER A CB     1 
ATOM   1504 O  OG     . SER A 1  192 ? 2.36529   11.35273  43.48223  1.000 26.05397  ? 222 SER A OG     1 
ATOM   1505 N  N      . GLY A 1  193 ? 2.16222   10.82168  39.43496  1.000 19.59055  ? 223 GLY A N      1 
ATOM   1506 C  CA     . GLY A 1  193 ? 2.48999   11.55215  38.22335  1.000 20.10664  ? 223 GLY A CA     1 
ATOM   1507 C  C      . GLY A 1  193 ? 2.72806   13.04584  38.42657  1.000 25.89418  ? 223 GLY A C      1 
ATOM   1508 O  O      . GLY A 1  193 ? 3.53128   13.64406  37.71124  1.000 24.64712  ? 223 GLY A O      1 
ATOM   1509 N  N      . ASP A 1  194 ? 1.99541   13.67784  39.35934  1.000 26.11698  ? 224 ASP A N      1 
ATOM   1510 C  CA     . ASP A 1  194 ? 2.18597   15.11412  39.63550  1.000 24.49129  ? 224 ASP A CA     1 
ATOM   1511 C  C      . ASP A 1  194 ? 3.61778   15.42354  40.07119  1.000 29.39391  ? 224 ASP A C      1 
ATOM   1512 O  O      . ASP A 1  194 ? 4.12216   16.55397  39.88244  1.000 26.41237  ? 224 ASP A O      1 
ATOM   1513 C  CB     . ASP A 1  194 ? 1.24466   15.55894  40.73931  1.000 26.51791  ? 224 ASP A CB     1 
ATOM   1514 C  CG     . ASP A 1  194 ? 1.44540   14.76343  41.99630  1.000 27.98209  ? 224 ASP A CG     1 
ATOM   1515 O  OD1    . ASP A 1  194 ? 1.42266   13.51948  41.88394  1.000 29.96675  ? 224 ASP A OD1    1 
ATOM   1516 O  OD2    . ASP A 1  194 ? 1.67600   15.34809  43.08385  1.000 28.96609  ? 224 ASP A OD2    1 
ATOM   1517 N  N      . VAL A 1  195 ? 4.26244   14.44364  40.71938  1.000 25.79747  ? 225 VAL A N      1 
ATOM   1518 C  CA     . VAL A 1  195 ? 5.63064   14.63678  41.17468  1.000 21.98618  ? 225 VAL A CA     1 
ATOM   1519 C  C      . VAL A 1  195 ? 6.55000   14.98347  40.01287  1.000 20.56515  ? 225 VAL A C      1 
ATOM   1520 O  O      . VAL A 1  195 ? 7.50186   15.74757  40.18782  1.000 23.16279  ? 225 VAL A O      1 
ATOM   1521 C  CB     . VAL A 1  195 ? 6.10896   13.37932  41.93538  1.000 21.80901  ? 225 VAL A CB     1 
ATOM   1522 C  CG1    . VAL A 1  195 ? 7.61115   13.46402  42.23905  1.000 23.46641  ? 225 VAL A CG1    1 
ATOM   1523 C  CG2    . VAL A 1  195 ? 5.32775   13.21990  43.20788  1.000 19.87906  ? 225 VAL A CG2    1 
ATOM   1524 N  N      . ALA A 1  196 ? 6.30258   14.42917  38.81488  1.000 22.11425  ? 226 ALA A N      1 
ATOM   1525 C  CA     . ALA A 1  196 ? 7.15965   14.73798  37.66881  1.000 23.27405  ? 226 ALA A CA     1 
ATOM   1526 C  C      . ALA A 1  196 ? 7.16829   16.23094  37.36793  1.000 28.06521  ? 226 ALA A C      1 
ATOM   1527 O  O      . ALA A 1  196 ? 8.22588   16.81921  37.08555  1.000 25.11654  ? 226 ALA A O      1 
ATOM   1528 C  CB     . ALA A 1  196 ? 6.73792   13.95453  36.43086  1.000 23.94049  ? 226 ALA A CB     1 
ATOM   1529 N  N      . SER A 1  197 ? 5.99091   16.86230  37.37814  1.000 25.11097  ? 227 SER A N      1 
ATOM   1530 C  CA     . SER A 1  197 ? 5.94809   18.29474  37.09707  1.000 23.99051  ? 227 SER A CA     1 
ATOM   1531 C  C      . SER A 1  197 ? 6.67274   19.08092  38.18165  1.000 21.82396  ? 227 SER A C      1 
ATOM   1532 O  O      . SER A 1  197 ? 7.40177   20.04702  37.88792  1.000 25.34963  ? 227 SER A O      1 
ATOM   1533 C  CB     . SER A 1  197 ? 4.49378   18.76537  36.96726  1.000 29.76063  ? 227 SER A CB     1 
ATOM   1534 O  OG     . SER A 1  197 ? 3.92185   18.25169  35.77706  1.000 31.53133  ? 227 SER A OG     1 
ATOM   1535 N  N      . GLN A 1  198 ? 6.48587   18.68866  39.44312  1.000 22.23444  ? 228 GLN A N      1 
ATOM   1536 C  CA     . GLN A 1  198 ? 7.13905   19.44034  40.51367  1.000 20.76527  ? 228 GLN A CA     1 
ATOM   1537 C  C      . GLN A 1  198 ? 8.66635   19.31519  40.41735  1.000 22.43693  ? 228 GLN A C      1 
ATOM   1538 O  O      . GLN A 1  198 ? 9.40555   20.30063  40.59516  1.000 21.04958  ? 228 GLN A O      1 
ATOM   1539 C  CB     . GLN A 1  198 ? 6.62806   18.94431  41.86237  1.000 21.48935  ? 228 GLN A CB     1 
ATOM   1540 C  CG     . GLN A 1  198 ? 5.15008   19.27484  42.03965  1.000 31.46806  ? 228 GLN A CG     1 
ATOM   1541 C  CD     . GLN A 1  198 ? 4.52309   18.58009  43.22620  1.000 45.03874  ? 228 GLN A CD     1 
ATOM   1542 O  OE1    . GLN A 1  198 ? 4.81418   18.90256  44.38412  1.000 41.35080  ? 228 GLN A OE1    1 
ATOM   1543 N  NE2    . GLN A 1  198 ? 3.66256   17.59108  42.94353  1.000 41.71264  ? 228 GLN A NE2    1 
ATOM   1544 N  N      . VAL A 1  199 ? 9.15520   18.10191  40.14505  1.000 24.22740  ? 229 VAL A N      1 
ATOM   1545 C  CA     . VAL A 1  199 ? 10.59713  17.89007  40.02433  1.000 21.96863  ? 229 VAL A CA     1 
ATOM   1546 C  C      . VAL A 1  199 ? 11.14460  18.65704  38.83189  1.000 19.53133  ? 229 VAL A C      1 
ATOM   1547 O  O      . VAL A 1  199 ? 12.17610  19.33015  38.93352  1.000 26.37416  ? 229 VAL A O      1 
ATOM   1548 C  CB     . VAL A 1  199 ? 10.91497  16.38289  39.93190  1.000 22.09681  ? 229 VAL A CB     1 
ATOM   1549 C  CG1    . VAL A 1  199 ? 12.37657  16.15368  39.48230  1.000 18.91879  ? 229 VAL A CG1    1 
ATOM   1550 C  CG2    . VAL A 1  199 ? 10.67473  15.73571  41.28828  1.000 17.89076  ? 229 VAL A CG2    1 
ATOM   1551 N  N      . TYR A 1  200 ? 10.47433  18.57072  37.67537  1.000 23.21140  ? 230 TYR A N      1 
ATOM   1552 C  CA     . TYR A 1  200 ? 10.96117  19.30740  36.51789  1.000 24.46289  ? 230 TYR A CA     1 
ATOM   1553 C  C      . TYR A 1  200 ? 11.02588  20.79242  36.83037  1.000 24.35418  ? 230 TYR A C      1 
ATOM   1554 O  O      . TYR A 1  200 ? 12.02031  21.45446  36.51289  1.000 27.78198  ? 230 TYR A O      1 
ATOM   1555 C  CB     . TYR A 1  200 ? 10.07685  19.07266  35.28936  1.000 24.92415  ? 230 TYR A CB     1 
ATOM   1556 C  CG     . TYR A 1  200 ? 10.59295  19.77025  34.04988  1.000 26.37393  ? 230 TYR A CG     1 
ATOM   1557 C  CD1    . TYR A 1  200 ? 11.68878  19.26395  33.35997  1.000 32.76203  ? 230 TYR A CD1    1 
ATOM   1558 C  CD2    . TYR A 1  200 ? 10.01470  20.94842  33.58399  1.000 36.29510  ? 230 TYR A CD2    1 
ATOM   1559 C  CE1    . TYR A 1  200 ? 12.18780  19.89334  32.23331  1.000 38.39870  ? 230 TYR A CE1    1 
ATOM   1560 C  CE2    . TYR A 1  200 ? 10.51161  21.58956  32.45307  1.000 38.41099  ? 230 TYR A CE2    1 
ATOM   1561 C  CZ     . TYR A 1  200 ? 11.59514  21.05881  31.78351  1.000 42.71666  ? 230 TYR A CZ     1 
ATOM   1562 O  OH     . TYR A 1  200 ? 12.10375  21.68629  30.66402  1.000 47.56746  ? 230 TYR A OH     1 
ATOM   1563 N  N      . ASN A 1  201 ? 10.00488  21.31530  37.51756  1.000 23.92946  ? 231 ASN A N      1 
ATOM   1564 C  CA     . ASN A 1  201 ? 9.99701   22.74706  37.83639  1.000 28.60040  ? 231 ASN A CA     1 
ATOM   1565 C  C      . ASN A 1  201 ? 11.18246  23.13564  38.72023  1.000 28.29922  ? 231 ASN A C      1 
ATOM   1566 O  O      . ASN A 1  201 ? 11.81949  24.17771  38.48805  1.000 31.80827  ? 231 ASN A O      1 
ATOM   1567 C  CB     . ASN A 1  201 ? 8.66852   23.13405  38.49071  1.000 24.31284  ? 231 ASN A CB     1 
ATOM   1568 C  CG     . ASN A 1  201 ? 8.56375   24.63942  38.77635  1.000 37.48779  ? 231 ASN A CG     1 
ATOM   1569 O  OD1    . ASN A 1  201 ? 8.66294   25.06634  39.92252  1.000 45.14414  ? 231 ASN A OD1    1 
ATOM   1570 N  ND2    . ASN A 1  201 ? 8.39794   25.43742  37.72984  1.000 49.25165  ? 231 ASN A ND2    1 
ATOM   1571 N  N      . VAL A 1  202 ? 11.49585  22.33004  39.75066  1.000 23.06656  ? 232 VAL A N      1 
ATOM   1572 C  CA     . VAL A 1  202 ? 12.55654  22.74004  40.67815  1.000 25.67450  ? 232 VAL A CA     1 
ATOM   1573 C  C      . VAL A 1  202 ? 13.96277  22.35284  40.21129  1.000 33.34652  ? 232 VAL A C      1 
ATOM   1574 O  O      . VAL A 1  202 ? 14.94357  22.94716  40.69293  1.000 29.83148  ? 232 VAL A O      1 
ATOM   1575 C  CB     . VAL A 1  202 ? 12.28371  22.19129  42.09830  1.000 23.79568  ? 232 VAL A CB     1 
ATOM   1576 C  CG1    . VAL A 1  202 ? 12.55110  20.67478  42.19198  1.000 22.41755  ? 232 VAL A CG1    1 
ATOM   1577 C  CG2    . VAL A 1  202 ? 13.05645  22.94654  43.14065  1.000 34.43754  ? 232 VAL A CG2    1 
ATOM   1578 N  N      . SER A 1  203 ? 14.09223  21.44688  39.23157  1.000 24.84588  ? 233 SER A N      1 
ATOM   1579 C  CA     . SER A 1  203 ? 15.38858  20.83715  38.91907  1.000 24.04696  ? 233 SER A CA     1 
ATOM   1580 C  C      . SER A 1  203 ? 16.48581  21.86653  38.63924  1.000 29.00966  ? 233 SER A C      1 
ATOM   1581 O  O      . SER A 1  203 ? 17.63518  21.69599  39.06540  1.000 24.72989  ? 233 SER A O      1 
ATOM   1582 C  CB     . SER A 1  203 ? 15.23874  19.87213  37.74302  1.000 22.04362  ? 233 SER A CB     1 
ATOM   1583 O  OG     . SER A 1  203 ? 14.80460  20.50725  36.55685  1.000 28.44461  ? 233 SER A OG     1 
ATOM   1584 N  N      . LYS A 1  204 ? 16.17179  22.92132  37.89533  1.000 28.27622  ? 234 LYS A N      1 
ATOM   1585 C  CA     . LYS A 1  204 ? 17.23989  23.83959  37.52457  1.000 29.55079  ? 234 LYS A CA     1 
ATOM   1586 C  C      . LYS A 1  204 ? 17.75770  24.67510  38.69344  1.000 26.94990  ? 234 LYS A C      1 
ATOM   1587 O  O      . LYS A 1  204 ? 18.81086  25.30208  38.55073  1.000 30.57676  ? 234 LYS A O      1 
ATOM   1588 C  CB     . LYS A 1  204 ? 16.75425  24.74528  36.38885  1.000 29.77645  ? 234 LYS A CB     1 
ATOM   1589 C  CG     . LYS A 1  204 ? 16.68465  24.03170  35.04138  1.000 39.98072  ? 234 LYS A CG     1 
ATOM   1590 C  CD     . LYS A 1  204 ? 15.69889  24.70342  34.09478  1.000 60.52616  ? 234 LYS A CD     1 
ATOM   1591 C  CE     . LYS A 1  204 ? 14.94919  23.68825  33.22272  1.000 58.92183  ? 234 LYS A CE     1 
ATOM   1592 N  NZ     . LYS A 1  204 ? 13.72118  23.12860  33.87186  1.000 50.58858  ? 234 LYS A NZ     1 
ATOM   1593 N  N      . SER A 1  205 ? 17.09869  24.68291  39.85120  1.000 23.58027  ? 235 SER A N      1 
ATOM   1594 C  CA     . SER A 1  205 ? 17.60844  25.45706  40.98394  1.000 25.80688  ? 235 SER A CA     1 
ATOM   1595 C  C      . SER A 1  205 ? 18.26640  24.60193  42.05077  1.000 25.06520  ? 235 SER A C      1 
ATOM   1596 O  O      . SER A 1  205 ? 18.79839  25.14003  43.02304  1.000 25.27854  ? 235 SER A O      1 
ATOM   1597 C  CB     . SER A 1  205 ? 16.48058  26.29512  41.59904  1.000 32.09619  ? 235 SER A CB     1 
ATOM   1598 O  OG     . SER A 1  205 ? 15.58538  25.49341  42.34649  1.000 39.26490  ? 235 SER A OG     1 
ATOM   1599 N  N      . VAL A 1  206 ? 18.26420  23.28541  41.87921  1.000 19.58274  ? 236 VAL A N      1 
ATOM   1600 C  CA     . VAL A 1  206 ? 18.80926  22.34370  42.84276  1.000 19.60990  ? 236 VAL A CA     1 
ATOM   1601 C  C      . VAL A 1  206 ? 20.24191  22.02282  42.42006  1.000 17.64876  ? 236 VAL A C      1 
ATOM   1602 O  O      . VAL A 1  206 ? 20.49678  21.84986  41.21866  1.000 19.21238  ? 236 VAL A O      1 
ATOM   1603 C  CB     . VAL A 1  206 ? 17.93505  21.07187  42.87716  1.000 22.45962  ? 236 VAL A CB     1 
ATOM   1604 C  CG1    . VAL A 1  206 ? 18.58009  19.98238  43.68487  1.000 19.94393  ? 236 VAL A CG1    1 
ATOM   1605 C  CG2    . VAL A 1  206 ? 16.50568  21.41787  43.39202  1.000 23.65851  ? 236 VAL A CG2    1 
ATOM   1606 N  N      . PRO A 1  207 ? 21.19653  21.94444  43.34121  1.000 19.12943  ? 237 PRO A N      1 
ATOM   1607 C  CA     . PRO A 1  207 ? 22.58131  21.61507  42.94216  1.000 20.54538  ? 237 PRO A CA     1 
ATOM   1608 C  C      . PRO A 1  207 ? 22.65765  20.32417  42.13002  1.000 20.66421  ? 237 PRO A C      1 
ATOM   1609 O  O      . PRO A 1  207 ? 22.09065  19.30657  42.49863  1.000 20.92428  ? 237 PRO A O      1 
ATOM   1610 C  CB     . PRO A 1  207 ? 23.30825  21.46887  44.28040  1.000 25.53603  ? 237 PRO A CB     1 
ATOM   1611 C  CG     . PRO A 1  207 ? 22.48669  22.27875  45.23629  1.000 23.61571  ? 237 PRO A CG     1 
ATOM   1612 C  CD     . PRO A 1  207 ? 21.07307  22.09049  44.80167  1.000 19.00369  ? 237 PRO A CD     1 
ATOM   1613 N  N      . TYR A 1  208 ? 23.38519  20.36918  41.02144  1.000 21.10309  ? 238 TYR A N      1 
ATOM   1614 C  CA     . TYR A 1  208 ? 23.51578  19.20034  40.16779  1.000 20.67007  ? 238 TYR A CA     1 
ATOM   1615 C  C      . TYR A 1  208 ? 24.39395  18.13907  40.82645  1.000 21.58452  ? 238 TYR A C      1 
ATOM   1616 O  O      . TYR A 1  208 ? 25.36636  18.45476  41.52185  1.000 23.55483  ? 238 TYR A O      1 
ATOM   1617 C  CB     . TYR A 1  208 ? 24.12947  19.60611  38.82688  1.000 21.89512  ? 238 TYR A CB     1 
ATOM   1618 C  CG     . TYR A 1  208 ? 24.45273  18.42519  37.94546  1.000 26.30576  ? 238 TYR A CG     1 
ATOM   1619 C  CD1    . TYR A 1  208 ? 23.47166  17.84473  37.14959  1.000 23.57975  ? 238 TYR A CD1    1 
ATOM   1620 C  CD2    . TYR A 1  208 ? 25.73344  17.86916  37.91991  1.000 24.30971  ? 238 TYR A CD2    1 
ATOM   1621 C  CE1    . TYR A 1  208 ? 23.75811  16.76636  36.34933  1.000 27.77730  ? 238 TYR A CE1    1 
ATOM   1622 C  CE2    . TYR A 1  208 ? 26.02316  16.78840  37.11307  1.000 30.73813  ? 238 TYR A CE2    1 
ATOM   1623 C  CZ     . TYR A 1  208 ? 25.03094  16.24641  36.32818  1.000 33.19028  ? 238 TYR A CZ     1 
ATOM   1624 O  OH     . TYR A 1  208 ? 25.31029  15.16116  35.51358  1.000 37.66954  ? 238 TYR A OH     1 
ATOM   1625 N  N      . ILE A 1  209 ? 24.03968  16.87515  40.61654  1.000 20.72678  ? 239 ILE A N      1 
ATOM   1626 C  CA     . ILE A 1  209 ? 24.92507  15.75796  40.94387  1.000 21.14400  ? 239 ILE A CA     1 
ATOM   1627 C  C      . ILE A 1  209 ? 24.72547  14.68269  39.88926  1.000 21.62090  ? 239 ILE A C      1 
ATOM   1628 O  O      . ILE A 1  209 ? 23.60793  14.47177  39.40333  1.000 16.79937  ? 239 ILE A O      1 
ATOM   1629 C  CB     . ILE A 1  209 ? 24.70364  15.20955  42.37223  1.000 19.69321  ? 239 ILE A CB     1 
ATOM   1630 C  CG1    . ILE A 1  209 ? 25.81413  14.21565  42.72011  1.000 17.51612  ? 239 ILE A CG1    1 
ATOM   1631 C  CG2    . ILE A 1  209 ? 23.31398  14.55545  42.53372  1.000 15.50779  ? 239 ILE A CG2    1 
ATOM   1632 C  CD1    . ILE A 1  209 ? 25.78516  13.73538  44.16616  1.000 17.85262  ? 239 ILE A CD1    1 
ATOM   1633 N  N      . LYS A 1  210 ? 25.82369  14.02406  39.50764  1.000 17.43124  ? 240 LYS A N      1 
ATOM   1634 C  CA     . LYS A 1  210 ? 25.80081  13.08113  38.41004  1.000 22.37075  ? 240 LYS A CA     1 
ATOM   1635 C  C      . LYS A 1  210 ? 25.15094  11.75511  38.77529  1.000 19.03450  ? 240 LYS A C      1 
ATOM   1636 O  O      . LYS A 1  210 ? 24.95316  10.93146  37.88852  1.000 21.28471  ? 240 LYS A O      1 
ATOM   1637 C  CB     . LYS A 1  210 ? 27.23420  12.84369  37.93299  1.000 25.33654  ? 240 LYS A CB     1 
ATOM   1638 C  CG     . LYS A 1  210 ? 28.11663  12.19656  38.99400  1.000 21.59683  ? 240 LYS A CG     1 
ATOM   1639 C  CD     . LYS A 1  210 ? 29.55967  12.00486  38.50368  1.000 27.66316  ? 240 LYS A CD     1 
ATOM   1640 C  CE     . LYS A 1  210 ? 30.40125  11.31261  39.56805  1.000 31.40577  ? 240 LYS A CE     1 
ATOM   1641 N  NZ     . LYS A 1  210 ? 31.88691  11.55386  39.43640  1.000 38.23451  ? 240 LYS A NZ     1 
ATOM   1642 N  N      . LEU A 1  211 ? 24.81444  11.52571  40.04039  1.000 18.01255  ? 241 LEU A N      1 
ATOM   1643 C  CA     . LEU A 1  211 ? 24.09380  10.31212  40.43801  1.000 16.90156  ? 241 LEU A CA     1 
ATOM   1644 C  C      . LEU A 1  211 ? 22.60003  10.64068  40.44849  1.000 16.97866  ? 241 LEU A C      1 
ATOM   1645 O  O      . LEU A 1  211 ? 22.14930  11.46445  41.25247  1.000 17.56786  ? 241 LEU A O      1 
ATOM   1646 C  CB     . LEU A 1  211 ? 24.56095  9.85196   41.80317  1.000 17.27576  ? 241 LEU A CB     1 
ATOM   1647 C  CG     . LEU A 1  211 ? 26.08681  9.64761   41.84049  1.000 22.08579  ? 241 LEU A CG     1 
ATOM   1648 C  CD1    . LEU A 1  211 ? 26.49845  9.27154   43.25753  1.000 23.64992  ? 241 LEU A CD1    1 
ATOM   1649 C  CD2    . LEU A 1  211 ? 26.50490  8.59063   40.82148  1.000 20.69691  ? 241 LEU A CD2    1 
ATOM   1650 N  N      . GLU A 1  212 ? 21.85872  10.06351  39.51161  1.000 19.95377  ? 242 GLU A N      1 
ATOM   1651 C  CA     . GLU A 1  212 ? 20.49495  10.53234  39.23794  1.000 17.35398  ? 242 GLU A CA     1 
ATOM   1652 C  C      . GLU A 1  212 ? 19.56201  10.32434  40.43230  1.000 17.08907  ? 242 GLU A C      1 
ATOM   1653 O  O      . GLU A 1  212 ? 18.67982  11.15685  40.68488  1.000 17.33102  ? 242 GLU A O      1 
ATOM   1654 C  CB     . GLU A 1  212 ? 19.95663  9.85201   37.96653  1.000 14.55005  ? 242 GLU A CB     1 
ATOM   1655 C  CG     . GLU A 1  212 ? 19.85403  8.32853   38.02736  1.000 18.38698  ? 242 GLU A CG     1 
ATOM   1656 C  CD     . GLU A 1  212 ? 18.53392  7.83094   38.65312  1.000 21.27454  ? 242 GLU A CD     1 
ATOM   1657 O  OE1    . GLU A 1  212 ? 17.50301  8.53819   38.55948  1.000 21.30768  ? 242 GLU A OE1    1 
ATOM   1658 O  OE2    . GLU A 1  212 ? 18.55624  6.74690   39.28571  1.000 17.64879  ? 242 GLU A OE2    1 
ATOM   1659 N  N      . ASP A 1  213 ? 19.70495  9.20410   41.16592  1.000 17.69022  ? 243 ASP A N      1 
ATOM   1660 C  CA     . ASP A 1  213 ? 18.78712  8.95895   42.28500  1.000 17.88025  ? 243 ASP A CA     1 
ATOM   1661 C  C      . ASP A 1  213 ? 19.01323  9.94128   43.42942  1.000 17.92652  ? 243 ASP A C      1 
ATOM   1662 O  O      . ASP A 1  213 ? 18.04783  10.41313  44.05063  1.000 16.27046  ? 243 ASP A O      1 
ATOM   1663 C  CB     . ASP A 1  213 ? 18.86134  7.49353   42.77415  1.000 14.82901  ? 243 ASP A CB     1 
ATOM   1664 C  CG     . ASP A 1  213 ? 20.27675  6.93932   42.91308  1.000 21.68635  ? 243 ASP A CG     1 
ATOM   1665 O  OD1    . ASP A 1  213 ? 21.27329  7.67222   42.77966  1.000 20.84863  ? 243 ASP A OD1    1 
ATOM   1666 O  OD2    . ASP A 1  213 ? 20.38005  5.71782   43.20632  1.000 16.99496  ? 243 ASP A OD2    1 
ATOM   1667 N  N      . VAL A 1  214 ? 20.27122  10.29987  43.69148  1.000 13.63195  ? 244 VAL A N      1 
ATOM   1668 C  CA     . VAL A 1  214 ? 20.55191  11.35930  44.65120  1.000 14.49681  ? 244 VAL A CA     1 
ATOM   1669 C  C      . VAL A 1  214 ? 19.98089  12.68642  44.15338  1.000 14.21385  ? 244 VAL A C      1 
ATOM   1670 O  O      . VAL A 1  214 ? 19.45199  13.47491  44.94259  1.000 16.61174  ? 244 VAL A O      1 
ATOM   1671 C  CB     . VAL A 1  214 ? 22.06669  11.46863  44.91580  1.000 14.13867  ? 244 VAL A CB     1 
ATOM   1672 C  CG1    . VAL A 1  214 ? 22.33472  12.57291  45.96681  1.000 16.35709  ? 244 VAL A CG1    1 
ATOM   1673 C  CG2    . VAL A 1  214 ? 22.59781  10.14153  45.43364  1.000 15.50155  ? 244 VAL A CG2    1 
ATOM   1674 N  N      . PHE A 1  215 ? 20.14711  12.98729  42.86711  1.000 14.40054  ? 245 PHE A N      1 
ATOM   1675 C  CA     . PHE A 1  215 ? 19.66205  14.27276  42.37334  1.000 17.12125  ? 245 PHE A CA     1 
ATOM   1676 C  C      . PHE A 1  215 ? 18.15288  14.38720  42.57853  1.000 17.98900  ? 245 PHE A C      1 
ATOM   1677 O  O      . PHE A 1  215 ? 17.64693  15.41999  43.04276  1.000 18.77816  ? 245 PHE A O      1 
ATOM   1678 C  CB     . PHE A 1  215 ? 20.02068  14.47906  40.90362  1.000 16.22193  ? 245 PHE A CB     1 
ATOM   1679 C  CG     . PHE A 1  215 ? 19.53932  15.81007  40.37026  1.000 17.94678  ? 245 PHE A CG     1 
ATOM   1680 C  CD1    . PHE A 1  215 ? 20.14210  16.98651  40.79109  1.000 18.13592  ? 245 PHE A CD1    1 
ATOM   1681 C  CD2    . PHE A 1  215 ? 18.45545  15.88182  39.52136  1.000 16.38629  ? 245 PHE A CD2    1 
ATOM   1682 C  CE1    . PHE A 1  215 ? 19.67982  18.23423  40.34787  1.000 19.92979  ? 245 PHE A CE1    1 
ATOM   1683 C  CE2    . PHE A 1  215 ? 17.99233  17.10602  39.05505  1.000 20.68782  ? 245 PHE A CE2    1 
ATOM   1684 C  CZ     . PHE A 1  215 ? 18.60399  18.29106  39.46953  1.000 24.18869  ? 245 PHE A CZ     1 
ATOM   1685 N  N      . VAL A 1  216 ? 17.41936  13.33176  42.23061  1.000 16.94894  ? 246 VAL A N      1 
ATOM   1686 C  CA     . VAL A 1  216 ? 15.97103  13.34057  42.46196  1.000 15.42578  ? 246 VAL A CA     1 
ATOM   1687 C  C      . VAL A 1  216 ? 15.67614  13.53448  43.94909  1.000 17.47969  ? 246 VAL A C      1 
ATOM   1688 O  O      . VAL A 1  216 ? 14.74885  14.26038  44.31912  1.000 20.10305  ? 246 VAL A O      1 
ATOM   1689 C  CB     . VAL A 1  216 ? 15.33063  12.05318  41.90282  1.000 17.66336  ? 246 VAL A CB     1 
ATOM   1690 C  CG1    . VAL A 1  216 ? 13.86831  11.95073  42.34416  1.000 21.47065  ? 246 VAL A CG1    1 
ATOM   1691 C  CG2    . VAL A 1  216 ? 15.45659  12.02581  40.37488  1.000 16.59570  ? 246 VAL A CG2    1 
ATOM   1692 N  N      . GLY A 1  217 ? 16.44074  12.88015  44.82174  1.000 17.30848  ? 247 GLY A N      1 
ATOM   1693 C  CA     . GLY A 1  217 ? 16.26930  13.10604  46.25691  1.000 15.50337  ? 247 GLY A CA     1 
ATOM   1694 C  C      . GLY A 1  217 ? 16.45951  14.56599  46.65396  1.000 20.78328  ? 247 GLY A C      1 
ATOM   1695 O  O      . GLY A 1  217 ? 15.71202  15.10918  47.48132  1.000 19.50725  ? 247 GLY A O      1 
ATOM   1696 N  N      . LEU A 1  218 ? 17.47581  15.21423  46.09314  1.000 14.78615  ? 248 LEU A N      1 
ATOM   1697 C  CA     . LEU A 1  218 ? 17.63690  16.65043  46.36297  1.000 19.92871  ? 248 LEU A CA     1 
ATOM   1698 C  C      . LEU A 1  218 ? 16.39651  17.43267  45.92671  1.000 22.00316  ? 248 LEU A C      1 
ATOM   1699 O  O      . LEU A 1  218 ? 15.94851  18.34668  46.62883  1.000 17.59457  ? 248 LEU A O      1 
ATOM   1700 C  CB     . LEU A 1  218 ? 18.88291  17.18847  45.67034  1.000 18.46990  ? 248 LEU A CB     1 
ATOM   1701 C  CG     . LEU A 1  218 ? 20.24229  16.75145  46.21854  1.000 18.70807  ? 248 LEU A CG     1 
ATOM   1702 C  CD1    . LEU A 1  218 ? 21.37101  17.18471  45.28797  1.000 19.13370  ? 248 LEU A CD1    1 
ATOM   1703 C  CD2    . LEU A 1  218 ? 20.46864  17.34312  47.63581  1.000 17.97397  ? 248 LEU A CD2    1 
ATOM   1704 N  N      . CYS A 1  219 ? 15.85161  17.11038  44.74800  1.000 18.05465  ? 249 CYS A N      1 
ATOM   1705 C  CA     . CYS A 1  219 ? 14.65319  17.80739  44.28855  1.000 20.02555  ? 249 CYS A CA     1 
ATOM   1706 C  C      . CYS A 1  219 ? 13.47003  17.56297  45.23011  1.000 20.32762  ? 249 CYS A C      1 
ATOM   1707 O  O      . CYS A 1  219 ? 12.72677  18.49653  45.56586  1.000 20.84462  ? 249 CYS A O      1 
ATOM   1708 C  CB     . CYS A 1  219 ? 14.30683  17.39111  42.85514  1.000 18.54787  ? 249 CYS A CB     1 
ATOM   1709 S  SG     . CYS A 1  219 ? 15.51923  17.87889  41.63691  1.000 20.50518  ? 249 CYS A SG     1 
ATOM   1710 N  N      . LEU A 1  220 ? 13.23037  16.30270  45.60226  1.000 17.16761  ? 250 LEU A N      1 
ATOM   1711 C  CA     . LEU A 1  220 ? 12.13359  15.98385  46.52215  1.000 18.15712  ? 250 LEU A CA     1 
ATOM   1712 C  C      . LEU A 1  220 ? 12.28823  16.71610  47.84396  1.000 24.80625  ? 250 LEU A C      1 
ATOM   1713 O  O      . LEU A 1  220 ? 11.30995  17.20132  48.43006  1.000 22.34574  ? 250 LEU A O      1 
ATOM   1714 C  CB     . LEU A 1  220 ? 12.08137  14.48750  46.79422  1.000 19.89427  ? 250 LEU A CB     1 
ATOM   1715 C  CG     . LEU A 1  220 ? 11.77649  13.59313  45.59058  1.000 18.38650  ? 250 LEU A CG     1 
ATOM   1716 C  CD1    . LEU A 1  220 ? 11.95346  12.16173  46.09958  1.000 17.12234  ? 250 LEU A CD1    1 
ATOM   1717 C  CD2    . LEU A 1  220 ? 10.36134  13.79543  45.08199  1.000 21.15438  ? 250 LEU A CD2    1 
ATOM   1718 N  N      . GLU A 1  221 ? 13.50725  16.77363  48.34844  1.000 17.19840  ? 251 GLU A N      1 
ATOM   1719 C  CA     . GLU A 1  221 ? 13.75950  17.51501  49.57639  1.000 17.78393  ? 251 GLU A CA     1 
ATOM   1720 C  C      . GLU A 1  221 ? 13.42271  18.99343  49.40991  1.000 19.38837  ? 251 GLU A C      1 
ATOM   1721 O  O      . GLU A 1  221 ? 12.82332  19.60491  50.30642  1.000 21.67120  ? 251 GLU A O      1 
ATOM   1722 C  CB     . GLU A 1  221 ? 15.22034  17.33311  49.96633  1.000 16.76222  ? 251 GLU A CB     1 
ATOM   1723 C  CG     . GLU A 1  221 ? 15.68007  18.19155  51.13578  1.000 20.87766  ? 251 GLU A CG     1 
ATOM   1724 C  CD     . GLU A 1  221 ? 17.12167  17.88829  51.44028  1.000 19.67695  ? 251 GLU A CD     1 
ATOM   1725 O  OE1    . GLU A 1  221 ? 17.99282  18.40185  50.70550  1.000 21.41346  ? 251 GLU A OE1    1 
ATOM   1726 O  OE2    . GLU A 1  221 ? 17.35959  17.07364  52.35533  1.000 20.64448  ? 251 GLU A OE2    1 
ATOM   1727 N  N      . ARG A 1  222 ? 13.81032  19.59148  48.28162  1.000 18.10726  ? 252 ARG A N      1 
ATOM   1728 C  CA     . ARG A 1  222 ? 13.46363  20.99831  48.06952  1.000 19.12200  ? 252 ARG A CA     1 
ATOM   1729 C  C      . ARG A 1  222 ? 11.95115  21.17896  48.03731  1.000 30.97530  ? 252 ARG A C      1 
ATOM   1730 O  O      . ARG A 1  222 ? 11.42851  22.20942  48.48592  1.000 26.22160  ? 252 ARG A O      1 
ATOM   1731 C  CB     . ARG A 1  222 ? 14.11001  21.52248  46.78481  1.000 21.33210  ? 252 ARG A CB     1 
ATOM   1732 C  CG     . ARG A 1  222 ? 13.67429  22.94020  46.32436  1.000 28.88478  ? 252 ARG A CG     1 
ATOM   1733 C  CD     . ARG A 1  222 ? 14.47429  24.06776  47.00868  1.000 28.60651  ? 252 ARG A CD     1 
ATOM   1734 N  NE     . ARG A 1  222 ? 15.88835  23.74375  47.19732  1.000 38.28959  ? 252 ARG A NE     1 
ATOM   1735 C  CZ     . ARG A 1  222 ? 16.88404  24.15960  46.41954  1.000 40.43269  ? 252 ARG A CZ     1 
ATOM   1736 N  NH1    . ARG A 1  222 ? 16.65991  24.89388  45.34761  1.000 32.59538  ? 252 ARG A NH1    1 
ATOM   1737 N  NH2    . ARG A 1  222 ? 18.14037  23.80586  46.71910  1.000 40.54846  ? 252 ARG A NH2    1 
ATOM   1738 N  N      . LEU A 1  223 ? 11.23728  20.17285  47.54035  1.000 23.81753  ? 253 LEU A N      1 
ATOM   1739 C  CA     . LEU A 1  223 ? 9.78439   20.18269  47.40021  1.000 22.50176  ? 253 LEU A CA     1 
ATOM   1740 C  C      . LEU A 1  223 ? 9.05094   19.78781  48.67820  1.000 23.02853  ? 253 LEU A C      1 
ATOM   1741 O  O      . LEU A 1  223 ? 7.81446   19.86102  48.70947  1.000 27.19197  ? 253 LEU A O      1 
ATOM   1742 C  CB     . LEU A 1  223 ? 9.39849   19.24309  46.25260  1.000 18.93020  ? 253 LEU A CB     1 
ATOM   1743 C  CG     . LEU A 1  223 ? 9.79341   19.69670  44.84725  1.000 22.85790  ? 253 LEU A CG     1 
ATOM   1744 C  CD1    . LEU A 1  223 ? 9.62724   18.57947  43.79165  1.000 21.78420  ? 253 LEU A CD1    1 
ATOM   1745 C  CD2    . LEU A 1  223 ? 8.96665   20.91619  44.47990  1.000 30.61761  ? 253 LEU A CD2    1 
ATOM   1746 N  N      . ASN A 1  224 ? 9.77243   19.38059  49.72033  1.000 20.39029  ? 254 ASN A N      1 
ATOM   1747 C  CA     . ASN A 1  224 ? 9.19839   18.89987  50.98223  1.000 27.78931  ? 254 ASN A CA     1 
ATOM   1748 C  C      . ASN A 1  224 ? 8.32858   17.65107  50.79226  1.000 35.22934  ? 254 ASN A C      1 
ATOM   1749 O  O      . ASN A 1  224 ? 7.39738   17.40190  51.57235  1.000 29.96367  ? 254 ASN A O      1 
ATOM   1750 C  CB     . ASN A 1  224 ? 8.43758   20.01310  51.71218  1.000 32.87526  ? 254 ASN A CB     1 
ATOM   1751 C  CG     . ASN A 1  224 ? 9.35894   21.15587  52.11025  1.000 39.04951  ? 254 ASN A CG     1 
ATOM   1752 O  OD1    . ASN A 1  224 ? 9.32184   22.23252  51.52491  1.000 47.07829  ? 254 ASN A OD1    1 
ATOM   1753 N  ND2    . ASN A 1  224 ? 10.20749  20.91028  53.10275  1.000 43.27309  ? 254 ASN A ND2    1 
ATOM   1754 N  N      . ILE A 1  225 ? 8.64326   16.86463  49.76065  1.000 27.15151  ? 255 ILE A N      1 
ATOM   1755 C  CA     . ILE A 1  225 ? 8.00722   15.56970  49.51145  1.000 26.70202  ? 255 ILE A CA     1 
ATOM   1756 C  C      . ILE A 1  225 ? 8.76376   14.50925  50.29981  1.000 32.56249  ? 255 ILE A C      1 
ATOM   1757 O  O      . ILE A 1  225 ? 9.98259   14.35952  50.15020  1.000 25.74438  ? 255 ILE A O      1 
ATOM   1758 C  CB     . ILE A 1  225 ? 7.98845   15.24910  48.00672  1.000 21.49714  ? 255 ILE A CB     1 
ATOM   1759 C  CG1    . ILE A 1  225 ? 7.09078   16.26533  47.28748  1.000 24.24471  ? 255 ILE A CG1    1 
ATOM   1760 C  CG2    . ILE A 1  225 ? 7.54763   13.79796  47.74991  1.000 23.68812  ? 255 ILE A CG2    1 
ATOM   1761 C  CD1    . ILE A 1  225 ? 7.19561   16.27433  45.76058  1.000 26.26354  ? 255 ILE A CD1    1 
ATOM   1762 N  N      . ARG A 1  226 ? 8.05622   13.81634  51.18937  1.000 29.83762  ? 256 ARG A N      1 
ATOM   1763 C  CA     . ARG A 1  226 ? 8.64868   12.81697  52.06428  1.000 32.91519  ? 256 ARG A CA     1 
ATOM   1764 C  C      . ARG A 1  226 ? 8.61017   11.43826  51.40829  1.000 27.48382  ? 256 ARG A C      1 
ATOM   1765 O  O      . ARG A 1  226 ? 7.60955   11.05854  50.79521  1.000 28.60034  ? 256 ARG A O      1 
ATOM   1766 C  CB     . ARG A 1  226 ? 7.87348   12.77465  53.38123  1.000 39.18785  ? 256 ARG A CB     1 
ATOM   1767 C  CG     . ARG A 1  226 ? 7.72561   14.10938  54.13787  1.000 53.48382  ? 256 ARG A CG     1 
ATOM   1768 C  CD     . ARG A 1  226 ? 8.81857   14.37661  55.17813  1.000 70.21718  ? 256 ARG A CD     1 
ATOM   1769 N  NE     . ARG A 1  226 ? 8.47194   15.54310  55.99041  1.000 95.67944  ? 256 ARG A NE     1 
ATOM   1770 C  CZ     . ARG A 1  226 ? 8.89170   15.76320  57.23243  1.000 99.37296  ? 256 ARG A CZ     1 
ATOM   1771 N  NH1    . ARG A 1  226 ? 9.64857   14.88648  57.87650  1.000 92.28214  ? 256 ARG A NH1    1 
ATOM   1772 N  NH2    . ARG A 1  226 ? 8.51957   16.88006  57.85494  1.000 90.96967  ? 256 ARG A NH2    1 
ATOM   1773 N  N      . LEU A 1  227 ? 9.69838   10.68769  51.54004  1.000 24.65685  ? 257 LEU A N      1 
ATOM   1774 C  CA     . LEU A 1  227 ? 9.70073   9.31679   51.04131  1.000 24.83985  ? 257 LEU A CA     1 
ATOM   1775 C  C      . LEU A 1  227 ? 8.83038   8.44635   51.93256  1.000 24.16077  ? 257 LEU A C      1 
ATOM   1776 O  O      . LEU A 1  227 ? 8.80210   8.61805   53.15178  1.000 27.17823  ? 257 LEU A O      1 
ATOM   1777 C  CB     . LEU A 1  227 ? 11.12190  8.72362   51.05573  1.000 21.98334  ? 257 LEU A CB     1 
ATOM   1778 C  CG     . LEU A 1  227 ? 12.21034  9.55210   50.38475  1.000 26.04154  ? 257 LEU A CG     1 
ATOM   1779 C  CD1    . LEU A 1  227 ? 13.52505  8.77041   50.41025  1.000 22.00939  ? 257 LEU A CD1    1 
ATOM   1780 C  CD2    . LEU A 1  227 ? 11.80862  9.90012   48.98158  1.000 24.26283  ? 257 LEU A CD2    1 
ATOM   1781 N  N      . GLU A 1  228 ? 8.16139   7.45906   51.34233  1.000 26.25106  ? 258 GLU A N      1 
ATOM   1782 C  CA     . GLU A 1  228 ? 7.45534   6.50880   52.18789  1.000 28.15914  ? 258 GLU A CA     1 
ATOM   1783 C  C      . GLU A 1  228 ? 7.58881   5.09324   51.64574  1.000 19.34258  ? 258 GLU A C      1 
ATOM   1784 O  O      . GLU A 1  228 ? 7.74400   4.88571   50.44240  1.000 25.62660  ? 258 GLU A O      1 
ATOM   1785 C  CB     . GLU A 1  228 ? 5.98128   6.86392   52.37777  1.000 32.22098  ? 258 GLU A CB     1 
ATOM   1786 C  CG     . GLU A 1  228 ? 5.20767   7.15818   51.14237  1.000 42.34043  ? 258 GLU A CG     1 
ATOM   1787 C  CD     . GLU A 1  228 ? 3.79266   7.61429   51.48726  1.000 47.13787  ? 258 GLU A CD     1 
ATOM   1788 O  OE1    . GLU A 1  228 ? 2.94967   6.74722   51.81025  1.000 55.39138  ? 258 GLU A OE1    1 
ATOM   1789 O  OE2    . GLU A 1  228 ? 3.53801   8.83400   51.47225  1.000 43.29158  ? 258 GLU A OE2    1 
ATOM   1790 N  N      . GLU A 1  229 ? 7.54180   4.13229   52.56637  1.000 26.25408  ? 259 GLU A N      1 
ATOM   1791 C  CA     . GLU A 1  229 ? 7.56534   2.71792   52.20749  1.000 23.39933  ? 259 GLU A CA     1 
ATOM   1792 C  C      . GLU A 1  229 ? 6.26873   2.31841   51.51973  1.000 27.39877  ? 259 GLU A C      1 
ATOM   1793 O  O      . GLU A 1  229 ? 5.18067   2.75393   51.90556  1.000 29.60803  ? 259 GLU A O      1 
ATOM   1794 C  CB     . GLU A 1  229 ? 7.77230   1.87131   53.45717  1.000 26.29395  ? 259 GLU A CB     1 
ATOM   1795 C  CG     . GLU A 1  229 ? 9.03019   2.22324   54.23260  1.000 30.43949  ? 259 GLU A CG     1 
ATOM   1796 C  CD     . GLU A 1  229 ? 10.27353  1.54396   53.68182  1.000 32.52788  ? 259 GLU A CD     1 
ATOM   1797 O  OE1    . GLU A 1  229 ? 10.14914  0.72957   52.74263  1.000 32.31633  ? 259 GLU A OE1    1 
ATOM   1798 O  OE2    . GLU A 1  229 ? 11.37290  1.82888   54.19984  1.000 31.80140  ? 259 GLU A OE2    1 
ATOM   1799 N  N      . LEU A 1  230 ? 6.38542   1.48635   50.48404  1.000 25.96012  ? 260 LEU A N      1 
ATOM   1800 C  CA     . LEU A 1  230 ? 5.19277   1.12393   49.72719  1.000 28.11868  ? 260 LEU A CA     1 
ATOM   1801 C  C      . LEU A 1  230 ? 4.28224   0.21836   50.53719  1.000 27.76057  ? 260 LEU A C      1 
ATOM   1802 O  O      . LEU A 1  230 ? 3.05262   0.33835   50.45023  1.000 31.14119  ? 260 LEU A O      1 
ATOM   1803 C  CB     . LEU A 1  230 ? 5.58844   0.44218   48.41590  1.000 26.18827  ? 260 LEU A CB     1 
ATOM   1804 C  CG     . LEU A 1  230 ? 4.45874   -0.05292  47.53311  1.000 21.59179  ? 260 LEU A CG     1 
ATOM   1805 C  CD1    . LEU A 1  230 ? 3.54068   1.11655   47.06604  1.000 25.71837  ? 260 LEU A CD1    1 
ATOM   1806 C  CD2    . LEU A 1  230 ? 4.99823   -0.82755  46.33502  1.000 22.12502  ? 260 LEU A CD2    1 
ATOM   1807 N  N      . HIS A 1  231 ? 4.86706   -0.64742  51.35967  1.000 27.61942  ? 261 HIS A N      1 
ATOM   1808 C  CA     . HIS A 1  231 ? 4.12819   -1.71244  52.01098  1.000 31.87064  ? 261 HIS A CA     1 
ATOM   1809 C  C      . HIS A 1  231 ? 4.79412   -2.00393  53.34484  1.000 35.33599  ? 261 HIS A C      1 
ATOM   1810 O  O      . HIS A 1  231 ? 5.92762   -1.58286  53.60195  1.000 36.56777  ? 261 HIS A O      1 
ATOM   1811 C  CB     . HIS A 1  231 ? 4.08407   -2.95515  51.10774  1.000 32.71765  ? 261 HIS A CB     1 
ATOM   1812 C  CG     . HIS A 1  231 ? 3.25293   -4.07807  51.64471  1.000 37.55323  ? 261 HIS A CG     1 
ATOM   1813 N  ND1    . HIS A 1  231 ? 3.80242   -5.22694  52.16888  1.000 46.46297  ? 261 HIS A ND1    1 
ATOM   1814 C  CD2    . HIS A 1  231 ? 1.91128   -4.24357  51.69854  1.000 40.54936  ? 261 HIS A CD2    1 
ATOM   1815 C  CE1    . HIS A 1  231 ? 2.83516   -6.04151  52.55066  1.000 42.88789  ? 261 HIS A CE1    1 
ATOM   1816 N  NE2    . HIS A 1  231 ? 1.67736   -5.47066  52.27063  1.000 46.62597  ? 261 HIS A NE2    1 
ATOM   1817 N  N      . SER A 1  232 ? 4.06575   -2.71621  54.20819  1.000 34.52730  ? 262 SER A N      1 
ATOM   1818 C  CA     . SER A 1  232 ? 4.60072   -3.09991  55.50581  1.000 35.74111  ? 262 SER A CA     1 
ATOM   1819 C  C      . SER A 1  232 ? 5.75400   -4.07963  55.38386  1.000 41.84811  ? 262 SER A C      1 
ATOM   1820 O  O      . SER A 1  232 ? 6.52297   -4.23183  56.33664  1.000 44.79311  ? 262 SER A O      1 
ATOM   1821 C  CB     . SER A 1  232 ? 3.48728   -3.69717  56.36825  1.000 44.92360  ? 262 SER A CB     1 
ATOM   1822 O  OG     . SER A 1  232 ? 2.76093   -4.68137  55.64394  1.000 49.38284  ? 262 SER A OG     1 
ATOM   1823 N  N      . GLN A 1  233 ? 5.88352   -4.74870  54.23810  1.000 41.65443  ? 263 GLN A N      1 
ATOM   1824 C  CA     . GLN A 1  233 ? 6.96796   -5.67119  53.95061  1.000 40.91909  ? 263 GLN A CA     1 
ATOM   1825 C  C      . GLN A 1  233 ? 7.84563   -5.09453  52.84076  1.000 31.63021  ? 263 GLN A C      1 
ATOM   1826 O  O      . GLN A 1  233 ? 7.35887   -4.32783  52.00607  1.000 33.55422  ? 263 GLN A O      1 
ATOM   1827 C  CB     . GLN A 1  233 ? 6.42983   -7.03876  53.50261  1.000 37.38443  ? 263 GLN A CB     1 
ATOM   1828 C  CG     . GLN A 1  233 ? 5.51213   -7.73664  54.51030  1.000 43.95643  ? 263 GLN A CG     1 
ATOM   1829 C  CD     . GLN A 1  233 ? 6.21593   -8.04956  55.80579  1.000 49.68619  ? 263 GLN A CD     1 
ATOM   1830 O  OE1    . GLN A 1  233 ? 7.28356   -8.65895  55.80749  1.000 50.07197  ? 263 GLN A OE1    1 
ATOM   1831 N  NE2    . GLN A 1  233 ? 5.62299   -7.63093  56.92391  1.000 55.96099  ? 263 GLN A NE2    1 
ATOM   1832 N  N      . PRO A 1  234 ? 9.13605   -5.42526  52.81128  1.000 37.10697  ? 264 PRO A N      1 
ATOM   1833 C  CA     . PRO A 1  234 ? 9.98858   -4.95722  51.70733  1.000 28.67753  ? 264 PRO A CA     1 
ATOM   1834 C  C      . PRO A 1  234 ? 9.51083   -5.50306  50.36892  1.000 27.85911  ? 264 PRO A C      1 
ATOM   1835 O  O      . PRO A 1  234 ? 9.10130   -6.65913  50.25126  1.000 25.66078  ? 264 PRO A O      1 
ATOM   1836 C  CB     . PRO A 1  234 ? 11.37528  -5.49920  52.07074  1.000 26.04014  ? 264 PRO A CB     1 
ATOM   1837 C  CG     . PRO A 1  234 ? 11.08792  -6.67752  52.98997  1.000 37.05215  ? 264 PRO A CG     1 
ATOM   1838 C  CD     . PRO A 1  234 ? 9.88558   -6.24020  53.78511  1.000 33.09296  ? 264 PRO A CD     1 
ATOM   1839 N  N      . THR A 1  235 ? 9.56060   -4.65480  49.35670  1.000 19.51031  ? 265 THR A N      1 
ATOM   1840 C  CA     . THR A 1  235 ? 9.12448   -5.02060  48.01688  1.000 18.71942  ? 265 THR A CA     1 
ATOM   1841 C  C      . THR A 1  235 ? 10.08997  -4.63735  46.90852  1.000 17.53320  ? 265 THR A C      1 
ATOM   1842 O  O      . THR A 1  235 ? 9.89483   -5.08399  45.76637  1.000 18.74815  ? 265 THR A O      1 
ATOM   1843 C  CB     . THR A 1  235 ? 7.75425   -4.40220  47.72232  1.000 22.96936  ? 265 THR A CB     1 
ATOM   1844 O  OG1    . THR A 1  235 ? 7.81456   -2.97319  47.93392  1.000 21.42278  ? 265 THR A OG1    1 
ATOM   1845 C  CG2    . THR A 1  235 ? 6.70834   -5.01585  48.64209  1.000 22.93906  ? 265 THR A CG2    1 
ATOM   1846 N  N      . PHE A 1  236 ? 11.10003  -3.81315  47.19649  1.000 19.14019  ? 266 PHE A N      1 
ATOM   1847 C  CA     . PHE A 1  236 ? 12.14894  -3.42860  46.25128  1.000 17.01854  ? 266 PHE A CA     1 
ATOM   1848 C  C      . PHE A 1  236 ? 13.47620  -4.00161  46.73145  1.000 17.56768  ? 266 PHE A C      1 
ATOM   1849 O  O      . PHE A 1  236 ? 13.84140  -3.82338  47.90308  1.000 20.82941  ? 266 PHE A O      1 
ATOM   1850 C  CB     . PHE A 1  236 ? 12.25930  -1.90101  46.17108  1.000 15.45557  ? 266 PHE A CB     1 
ATOM   1851 C  CG     . PHE A 1  236 ? 11.04093  -1.22800  45.62130  1.000 16.97881  ? 266 PHE A CG     1 
ATOM   1852 C  CD1    . PHE A 1  236 ? 9.93479   -0.97627  46.43424  1.000 18.01058  ? 266 PHE A CD1    1 
ATOM   1853 C  CD2    . PHE A 1  236 ? 11.00150  -0.83175  44.29104  1.000 17.07947  ? 266 PHE A CD2    1 
ATOM   1854 C  CE1    . PHE A 1  236 ? 8.82521   -0.32390  45.92578  1.000 18.71901  ? 266 PHE A CE1    1 
ATOM   1855 C  CE2    . PHE A 1  236 ? 9.88260   -0.17802  43.76397  1.000 19.14617  ? 266 PHE A CE2    1 
ATOM   1856 C  CZ     . PHE A 1  236 ? 8.77934   0.06020   44.58267  1.000 18.76248  ? 266 PHE A CZ     1 
ATOM   1857 N  N      . PHE A 1  237 ? 14.22962  -4.63626  45.83028  1.000 16.97343  ? 267 PHE A N      1 
ATOM   1858 C  CA     . PHE A 1  237 ? 15.42494  -5.38674  46.22488  1.000 17.67996  ? 267 PHE A CA     1 
ATOM   1859 C  C      . PHE A 1  237 ? 16.59327  -5.03140  45.31029  1.000 17.54909  ? 267 PHE A C      1 
ATOM   1860 O  O      . PHE A 1  237 ? 16.94347  -5.78057  44.38175  1.000 17.50025  ? 267 PHE A O      1 
ATOM   1861 C  CB     . PHE A 1  237 ? 15.09852  -6.88610  46.23924  1.000 18.94007  ? 267 PHE A CB     1 
ATOM   1862 C  CG     . PHE A 1  237 ? 14.04830  -7.23707  47.24753  1.000 18.28411  ? 267 PHE A CG     1 
ATOM   1863 C  CD1    . PHE A 1  237 ? 14.39461  -7.46646  48.57387  1.000 21.93547  ? 267 PHE A CD1    1 
ATOM   1864 C  CD2    . PHE A 1  237 ? 12.70687  -7.28703  46.89609  1.000 16.02967  ? 267 PHE A CD2    1 
ATOM   1865 C  CE1    . PHE A 1  237 ? 13.42458  -7.75612  49.51932  1.000 23.21463  ? 267 PHE A CE1    1 
ATOM   1866 C  CE2    . PHE A 1  237 ? 11.73179  -7.59173  47.84257  1.000 17.11217  ? 267 PHE A CE2    1 
ATOM   1867 C  CZ     . PHE A 1  237 ? 12.09554  -7.81945  49.15548  1.000 21.13360  ? 267 PHE A CZ     1 
ATOM   1868 N  N      . PRO A 1  238 ? 17.20728  -3.86427  45.53257  1.000 19.02535  ? 268 PRO A N      1 
ATOM   1869 C  CA     . PRO A 1  238 ? 18.38815  -3.48263  44.73821  1.000 16.82192  ? 268 PRO A CA     1 
ATOM   1870 C  C      . PRO A 1  238 ? 19.53543  -4.46906  44.87231  1.000 18.33664  ? 268 PRO A C      1 
ATOM   1871 O  O      . PRO A 1  238 ? 20.43264  -4.47609  44.01213  1.000 19.93212  ? 268 PRO A O      1 
ATOM   1872 C  CB     . PRO A 1  238 ? 18.76483  -2.10116  45.31328  1.000 15.45892  ? 268 PRO A CB     1 
ATOM   1873 C  CG     . PRO A 1  238 ? 17.47640  -1.59938  45.96644  1.000 18.09754  ? 268 PRO A CG     1 
ATOM   1874 C  CD     . PRO A 1  238 ? 16.82483  -2.82927  46.51092  1.000 19.49164  ? 268 PRO A CD     1 
ATOM   1875 N  N      . GLY A 1  239 ? 19.56811  -5.23486  45.95244  1.000 18.47071  ? 269 GLY A N      1 
ATOM   1876 C  CA     . GLY A 1  239 ? 20.62676  -6.22383  46.17601  1.000 20.59085  ? 269 GLY A CA     1 
ATOM   1877 C  C      . GLY A 1  239 ? 20.38386  -7.55172  45.50374  1.000 26.65750  ? 269 GLY A C      1 
ATOM   1878 O  O      . GLY A 1  239 ? 21.26392  -8.41963  45.51181  1.000 21.81619  ? 269 GLY A O      1 
ATOM   1879 N  N      . GLY A 1  240 ? 19.21497  -7.73488  44.91041  1.000 20.58114  ? 270 GLY A N      1 
ATOM   1880 C  CA     . GLY A 1  240 ? 18.89178  -9.00215  44.28079  1.000 20.65087  ? 270 GLY A CA     1 
ATOM   1881 C  C      . GLY A 1  240 ? 18.29203  -9.97181  45.28436  1.000 20.13838  ? 270 GLY A C      1 
ATOM   1882 O  O      . GLY A 1  240 ? 18.24496  -9.71948  46.49852  1.000 20.44268  ? 270 GLY A O      1 
ATOM   1883 N  N      . LEU A 1  241 ? 17.82205  -11.10478 44.75644  1.000 19.05843  ? 271 LEU A N      1 
ATOM   1884 C  CA     . LEU A 1  241 ? 17.08707  -12.07755 45.54806  1.000 20.45950  ? 271 LEU A CA     1 
ATOM   1885 C  C      . LEU A 1  241 ? 17.31260  -13.47329 45.00077  1.000 22.24546  ? 271 LEU A C      1 
ATOM   1886 O  O      . LEU A 1  241 ? 17.42773  -13.67165 43.78721  1.000 25.51793  ? 271 LEU A O      1 
ATOM   1887 C  CB     . LEU A 1  241 ? 15.57696  -11.83028 45.47992  1.000 21.28435  ? 271 LEU A CB     1 
ATOM   1888 C  CG     . LEU A 1  241 ? 14.94346  -10.70755 46.27750  1.000 27.20303  ? 271 LEU A CG     1 
ATOM   1889 C  CD1    . LEU A 1  241 ? 13.44344  -10.65947 45.91678  1.000 22.48595  ? 271 LEU A CD1    1 
ATOM   1890 C  CD2    . LEU A 1  241 ? 15.16363  -10.89234 47.78135  1.000 23.56640  ? 271 LEU A CD2    1 
ATOM   1891 N  N      . ARG A 1  242 ? 17.27659  -14.44914 45.89952  1.000 19.46927  ? 272 ARG A N      1 
ATOM   1892 C  CA     . ARG A 1  242 ? 17.17616  -15.83166 45.46156  1.000 20.34255  ? 272 ARG A CA     1 
ATOM   1893 C  C      . ARG A 1  242 ? 15.78260  -16.09025 44.89909  1.000 18.65108  ? 272 ARG A C      1 
ATOM   1894 O  O      . ARG A 1  242 ? 14.77835  -15.78493 45.54733  1.000 20.86071  ? 272 ARG A O      1 
ATOM   1895 C  CB     . ARG A 1  242 ? 17.48976  -16.75117 46.64352  1.000 22.92832  ? 272 ARG A CB     1 
ATOM   1896 C  CG     . ARG A 1  242 ? 17.56868  -18.20442 46.28543  1.000 27.71242  ? 272 ARG A CG     1 
ATOM   1897 C  CD     . ARG A 1  242 ? 17.55487  -19.01987 47.55088  1.000 34.30660  ? 272 ARG A CD     1 
ATOM   1898 N  NE     . ARG A 1  242 ? 16.23927  -18.88112 48.14607  1.000 53.03575  ? 272 ARG A NE     1 
ATOM   1899 C  CZ     . ARG A 1  242 ? 15.80412  -19.55374 49.20018  1.000 72.26055  ? 272 ARG A CZ     1 
ATOM   1900 N  NH1    . ARG A 1  242 ? 16.61923  -20.30389 49.92783  1.000 60.38636  ? 272 ARG A NH1    1 
ATOM   1901 N  NH2    . ARG A 1  242 ? 14.51767  -19.46888 49.53329  1.000 64.33135  ? 272 ARG A NH2    1 
ATOM   1902 N  N      . PHE A 1  243 ? 15.71183  -16.60067 43.67102  1.000 18.61285  ? 273 PHE A N      1 
ATOM   1903 C  CA     . PHE A 1  243 ? 14.43318  -16.73457 42.99023  1.000 19.53925  ? 273 PHE A CA     1 
ATOM   1904 C  C      . PHE A 1  243 ? 13.56989  -17.86521 43.54752  1.000 24.77355  ? 273 PHE A C      1 
ATOM   1905 O  O      . PHE A 1  243 ? 14.03945  -18.97780 43.79852  1.000 22.01227  ? 273 PHE A O      1 
ATOM   1906 C  CB     . PHE A 1  243 ? 14.63128  -17.00260 41.50390  1.000 18.46443  ? 273 PHE A CB     1 
ATOM   1907 C  CG     . PHE A 1  243 ? 13.33459  -17.22383 40.77451  1.000 16.18925  ? 273 PHE A CG     1 
ATOM   1908 C  CD1    . PHE A 1  243 ? 12.53508  -16.13342 40.40704  1.000 19.08515  ? 273 PHE A CD1    1 
ATOM   1909 C  CD2    . PHE A 1  243 ? 12.88637  -18.51422 40.46556  1.000 21.68427  ? 273 PHE A CD2    1 
ATOM   1910 C  CE1    . PHE A 1  243 ? 11.34493  -16.31263 39.76530  1.000 20.07866  ? 273 PHE A CE1    1 
ATOM   1911 C  CE2    . PHE A 1  243 ? 11.67362  -18.69546 39.80881  1.000 23.27787  ? 273 PHE A CE2    1 
ATOM   1912 C  CZ     . PHE A 1  243 ? 10.90266  -17.60080 39.45306  1.000 24.29607  ? 273 PHE A CZ     1 
ATOM   1913 N  N      . SER A 1  244 ? 12.28564  -17.57374 43.71876  1.000 17.62888  ? 274 SER A N      1 
ATOM   1914 C  CA     . SER A 1  244 ? 11.25471  -18.59763 43.80087  1.000 23.14808  ? 274 SER A CA     1 
ATOM   1915 C  C      . SER A 1  244 ? 9.96196   -17.97230 43.31667  1.000 25.05156  ? 274 SER A C      1 
ATOM   1916 O  O      . SER A 1  244 ? 9.76047   -16.76597 43.46658  1.000 19.28407  ? 274 SER A O      1 
ATOM   1917 C  CB     . SER A 1  244 ? 11.09316  -19.15802 45.21216  1.000 24.20586  ? 274 SER A CB     1 
ATOM   1918 O  OG     . SER A 1  244 ? 10.46726  -18.22002 46.05893  1.000 25.45935  ? 274 SER A OG     1 
ATOM   1919 N  N      . VAL A 1  245 ? 9.10210   -18.79359 42.70929  1.000 19.46019  ? 275 VAL A N      1 
ATOM   1920 C  CA     . VAL A 1  245 ? 7.81240   -18.30524 42.20861  1.000 23.94266  ? 275 VAL A CA     1 
ATOM   1921 C  C      . VAL A 1  245 ? 7.05062   -17.59546 43.31607  1.000 18.83661  ? 275 VAL A C      1 
ATOM   1922 O  O      . VAL A 1  245 ? 6.52715   -16.48890 43.13265  1.000 22.19436  ? 275 VAL A O      1 
ATOM   1923 C  CB     . VAL A 1  245 ? 6.98942   -19.47660 41.62232  1.000 21.69713  ? 275 VAL A CB     1 
ATOM   1924 C  CG1    . VAL A 1  245 ? 5.49881   -19.14202 41.56760  1.000 25.36970  ? 275 VAL A CG1    1 
ATOM   1925 C  CG2    . VAL A 1  245 ? 7.50856   -19.86748 40.23359  1.000 24.51216  ? 275 VAL A CG2    1 
ATOM   1926 N  N      . CYS A 1  246 ? 6.94855   -18.23712 44.47858  1.000 22.18042  ? 276 CYS A N      1 
ATOM   1927 C  CA     . CYS A 1  246 ? 6.07935   -17.69085 45.51482  1.000 27.28667  ? 276 CYS A CA     1 
ATOM   1928 C  C      . CYS A 1  246 ? 6.62483   -16.37899 46.07049  1.000 25.70024  ? 276 CYS A C      1 
ATOM   1929 O  O      . CYS A 1  246 ? 5.85073   -15.47217 46.37774  1.000 25.45434  ? 276 CYS A O      1 
ATOM   1930 C  CB     . CYS A 1  246 ? 5.84729   -18.72506 46.60293  1.000 37.80622  ? 276 CYS A CB     1 
ATOM   1931 S  SG     . CYS A 1  246 ? 4.81597   -20.10498 45.90985  1.000 37.21599  ? 276 CYS A SG     1 
ATOM   1932 N  N      . LEU A 1  247 ? 7.94298   -16.26373 46.21442  1.000 20.30489  ? 277 LEU A N      1 
ATOM   1933 C  CA     . LEU A 1  247 ? 8.53062   -14.97667 46.59923  1.000 19.59119  ? 277 LEU A CA     1 
ATOM   1934 C  C      . LEU A 1  247 ? 8.28732   -13.92387 45.52768  1.000 21.62316  ? 277 LEU A C      1 
ATOM   1935 O  O      . LEU A 1  247 ? 7.88327   -12.78549 45.82850  1.000 23.33141  ? 277 LEU A O      1 
ATOM   1936 C  CB     . LEU A 1  247 ? 10.03818  -15.13703 46.85814  1.000 20.99444  ? 277 LEU A CB     1 
ATOM   1937 C  CG     . LEU A 1  247 ? 10.73897  -13.80835 47.15645  1.000 22.19168  ? 277 LEU A CG     1 
ATOM   1938 C  CD1    . LEU A 1  247 ? 10.15727  -13.15640 48.41664  1.000 26.86607  ? 277 LEU A CD1    1 
ATOM   1939 C  CD2    . LEU A 1  247 ? 12.25630  -13.97478 47.25392  1.000 23.23871  ? 277 LEU A CD2    1 
ATOM   1940 N  N      . PHE A 1  248 ? 8.53957   -14.26886 44.26340  1.000 19.48474  ? 278 PHE A N      1 
ATOM   1941 C  CA     . PHE A 1  248 ? 8.46491   -13.22642 43.24552  1.000 17.94767  ? 278 PHE A CA     1 
ATOM   1942 C  C      . PHE A 1  248 ? 7.04165   -12.77641 42.98488  1.000 26.14321  ? 278 PHE A C      1 
ATOM   1943 O  O      . PHE A 1  248 ? 6.85419   -11.68446 42.44580  1.000 22.39216  ? 278 PHE A O      1 
ATOM   1944 C  CB     . PHE A 1  248 ? 9.13044   -13.66608 41.95368  1.000 20.18885  ? 278 PHE A CB     1 
ATOM   1945 C  CG     . PHE A 1  248 ? 10.61525  -13.37610 41.95158  1.000 15.54381  ? 278 PHE A CG     1 
ATOM   1946 C  CD1    . PHE A 1  248 ? 11.35671  -13.67113 43.07918  1.000 16.34215  ? 278 PHE A CD1    1 
ATOM   1947 C  CD2    . PHE A 1  248 ? 11.23029  -12.74928 40.87602  1.000 14.79800  ? 278 PHE A CD2    1 
ATOM   1948 C  CE1    . PHE A 1  248 ? 12.71739  -13.41631 43.13431  1.000 21.13913  ? 278 PHE A CE1    1 
ATOM   1949 C  CE2    . PHE A 1  248 ? 12.63965  -12.46941 40.93418  1.000 17.22033  ? 278 PHE A CE2    1 
ATOM   1950 C  CZ     . PHE A 1  248 ? 13.34409  -12.80099 42.06683  1.000 18.77582  ? 278 PHE A CZ     1 
ATOM   1951 N  N      . ARG A 1  249 ? 6.04209   -13.56309 43.39951  1.000 20.88952  ? 279 ARG A N      1 
ATOM   1952 C  CA     . ARG A 1  249 ? 4.66814   -13.07091 43.33903  1.000 22.64421  ? 279 ARG A CA     1 
ATOM   1953 C  C      . ARG A 1  249 ? 4.37530   -11.98190 44.36194  1.000 23.90444  ? 279 ARG A C      1 
ATOM   1954 O  O      . ARG A 1  249 ? 3.30952   -11.35473 44.28370  1.000 25.69900  ? 279 ARG A O      1 
ATOM   1955 C  CB     . ARG A 1  249 ? 3.68262   -14.21872 43.57413  1.000 24.84912  ? 279 ARG A CB     1 
ATOM   1956 C  CG     . ARG A 1  249 ? 3.44548   -15.12300 42.39739  1.000 25.36395  ? 279 ARG A CG     1 
ATOM   1957 C  CD     . ARG A 1  249 ? 2.50531   -16.22731 42.89724  1.000 25.75350  ? 279 ARG A CD     1 
ATOM   1958 N  NE     . ARG A 1  249 ? 2.23121   -17.25975 41.90767  1.000 27.57876  ? 279 ARG A NE     1 
ATOM   1959 C  CZ     . ARG A 1  249 ? 1.39496   -18.27299 42.12642  1.000 41.23320  ? 279 ARG A CZ     1 
ATOM   1960 N  NH1    . ARG A 1  249 ? 0.74585   -18.39746 43.27534  1.000 36.82692  ? 279 ARG A NH1    1 
ATOM   1961 N  NH2    . ARG A 1  249 ? 1.21545   -19.18746 41.17763  1.000 37.47733  ? 279 ARG A NH2    1 
ATOM   1962 N  N      . ARG A 1  250 ? 5.22568   -11.79832 45.37202  1.000 22.85906  ? 280 ARG A N      1 
ATOM   1963 C  CA     . ARG A 1  250 ? 4.92989   -10.84860 46.43312  1.000 24.76418  ? 280 ARG A CA     1 
ATOM   1964 C  C      . ARG A 1  250 ? 6.05337   -9.82488  46.58707  1.000 20.94022  ? 280 ARG A C      1 
ATOM   1965 O  O      . ARG A 1  250 ? 6.34203   -9.35670  47.69052  1.000 22.86518  ? 280 ARG A O      1 
ATOM   1966 C  CB     . ARG A 1  250 ? 4.66451   -11.57989 47.75135  1.000 25.57934  ? 280 ARG A CB     1 
ATOM   1967 C  CG     . ARG A 1  250 ? 5.84094   -12.38849 48.27624  1.000 33.44720  ? 280 ARG A CG     1 
ATOM   1968 C  CD     . ARG A 1  250 ? 5.52029   -13.05952 49.62393  1.000 46.34340  ? 280 ARG A CD     1 
ATOM   1969 N  NE     . ARG A 1  250 ? 6.72521   -13.44011 50.36108  1.000 52.59475  ? 280 ARG A NE     1 
ATOM   1970 C  CZ     . ARG A 1  250 ? 7.29973   -14.63904 50.33132  1.000 50.42786  ? 280 ARG A CZ     1 
ATOM   1971 N  NH1    . ARG A 1  250 ? 6.87071   -15.59869 49.52401  1.000 51.85274  ? 280 ARG A NH1    1 
ATOM   1972 N  NH2    . ARG A 1  250 ? 8.34094   -14.87719 51.12469  1.000 51.51755  ? 280 ARG A NH2    1 
ATOM   1973 N  N      . ILE A 1  251 ? 6.69749   -9.47377  45.48456  1.000 18.51766  ? 281 ILE A N      1 
ATOM   1974 C  CA     . ILE A 1  251 ? 7.67206   -8.37874  45.47011  1.000 19.40961  ? 281 ILE A CA     1 
ATOM   1975 C  C      . ILE A 1  251 ? 7.31544   -7.47827  44.30373  1.000 19.23632  ? 281 ILE A C      1 
ATOM   1976 O  O      . ILE A 1  251 ? 6.54236   -7.85110  43.41887  1.000 21.34691  ? 281 ILE A O      1 
ATOM   1977 C  CB     . ILE A 1  251 ? 9.13043   -8.87629  45.32994  1.000 20.86214  ? 281 ILE A CB     1 
ATOM   1978 C  CG1    . ILE A 1  251 ? 9.34022   -9.47731  43.93826  1.000 23.03911  ? 281 ILE A CG1    1 
ATOM   1979 C  CG2    . ILE A 1  251 ? 9.50522   -9.85534  46.48160  1.000 21.05554  ? 281 ILE A CG2    1 
ATOM   1980 C  CD1    . ILE A 1  251 ? 10.82773  -9.72902  43.57670  1.000 23.65603  ? 281 ILE A CD1    1 
ATOM   1981 N  N      . VAL A 1  252 ? 7.87120   -6.27017  44.31453  1.000 17.70104  ? 282 VAL A N      1 
ATOM   1982 C  CA     . VAL A 1  252 ? 7.69500   -5.33570  43.21458  1.000 16.79193  ? 282 VAL A CA     1 
ATOM   1983 C  C      . VAL A 1  252 ? 8.90317   -5.34007  42.27881  1.000 17.54687  ? 282 VAL A C      1 
ATOM   1984 O  O      . VAL A 1  252 ? 8.75192   -5.36971  41.05934  1.000 17.46550  ? 282 VAL A O      1 
ATOM   1985 C  CB     . VAL A 1  252 ? 7.41894   -3.91331  43.75510  1.000 16.87586  ? 282 VAL A CB     1 
ATOM   1986 C  CG1    . VAL A 1  252 ? 7.54817   -2.91462  42.62191  1.000 17.10068  ? 282 VAL A CG1    1 
ATOM   1987 C  CG2    . VAL A 1  252 ? 5.99244   -3.84577  44.38133  1.000 21.15959  ? 282 VAL A CG2    1 
ATOM   1988 N  N      . ALA A 1  253 ? 10.12237  -5.30773  42.82194  1.000 16.12495  ? 283 ALA A N      1 
ATOM   1989 C  CA     . ALA A 1  253 ? 11.27700  -5.10448  41.95279  1.000 16.74837  ? 283 ALA A CA     1 
ATOM   1990 C  C      . ALA A 1  253 ? 12.47783  -5.85880  42.47793  1.000 14.26021  ? 283 ALA A C      1 
ATOM   1991 O  O      . ALA A 1  253 ? 12.73392  -5.85555  43.68354  1.000 17.46393  ? 283 ALA A O      1 
ATOM   1992 C  CB     . ALA A 1  253 ? 11.64873  -3.60246  41.83161  1.000 18.55631  ? 283 ALA A CB     1 
ATOM   1993 N  N      . CYS A 1  254 ? 13.18787  -6.51811  41.55578  1.000 17.21894  ? 284 CYS A N      1 
ATOM   1994 C  CA     . CYS A 1  254 ? 14.41570  -7.21678  41.89865  1.000 18.72750  ? 284 CYS A CA     1 
ATOM   1995 C  C      . CYS A 1  254 ? 15.48707  -6.90304  40.86037  1.000 12.37220  ? 284 CYS A C      1 
ATOM   1996 O  O      . CYS A 1  254 ? 15.25716  -7.03384  39.65108  1.000 15.89939  ? 284 CYS A O      1 
ATOM   1997 C  CB     . CYS A 1  254 ? 14.17103  -8.74185  41.96891  1.000 18.79484  ? 284 CYS A CB     1 
ATOM   1998 S  SG     . CYS A 1  254 ? 15.63220  -9.70126  42.48426  1.000 20.07377  ? 284 CYS A SG     1 
ATOM   1999 N  N      . HIS A 1  255 ? 16.67419  -6.57636  41.33953  1.000 17.65445  ? 285 HIS A N      1 
ATOM   2000 C  CA     . HIS A 1  255 ? 17.79576  -6.15620  40.51501  1.000 15.25998  ? 285 HIS A CA     1 
ATOM   2001 C  C      . HIS A 1  255 ? 18.70831  -7.34763  40.18076  1.000 18.82135  ? 285 HIS A C      1 
ATOM   2002 O  O      . HIS A 1  255 ? 18.53322  -8.47214  40.67150  1.000 20.77114  ? 285 HIS A O      1 
ATOM   2003 C  CB     . HIS A 1  255 ? 18.54136  -5.04977  41.27550  1.000 18.92788  ? 285 HIS A CB     1 
ATOM   2004 C  CG     . HIS A 1  255 ? 19.63350  -4.35293  40.52479  1.000 18.57103  ? 285 HIS A CG     1 
ATOM   2005 N  ND1    . HIS A 1  255 ? 20.80864  -3.98792  41.15016  1.000 20.15241  ? 285 HIS A ND1    1 
ATOM   2006 C  CD2    . HIS A 1  255 ? 19.71049  -3.85992  39.26502  1.000 21.38704  ? 285 HIS A CD2    1 
ATOM   2007 C  CE1    . HIS A 1  255 ? 21.58709  -3.35819  40.28914  1.000 23.62510  ? 285 HIS A CE1    1 
ATOM   2008 N  NE2    . HIS A 1  255 ? 20.93909  -3.25325  39.14507  1.000 19.56442  ? 285 HIS A NE2    1 
ATOM   2009 N  N      . PHE A 1  256 ? 19.71395  -7.08099  39.34119  1.000 20.03835  ? 286 PHE A N      1 
ATOM   2010 C  CA     . PHE A 1  256 ? 20.73843  -8.07000  39.01058  1.000 20.43279  ? 286 PHE A CA     1 
ATOM   2011 C  C      . PHE A 1  256 ? 20.16649  -9.22055  38.18901  1.000 23.37052  ? 286 PHE A C      1 
ATOM   2012 O  O      . PHE A 1  256 ? 20.52174  -10.37928 38.39639  1.000 22.78470  ? 286 PHE A O      1 
ATOM   2013 C  CB     . PHE A 1  256 ? 21.41893  -8.60015  40.27484  1.000 23.60570  ? 286 PHE A CB     1 
ATOM   2014 C  CG     . PHE A 1  256 ? 22.28866  -7.56948  40.96761  1.000 22.31637  ? 286 PHE A CG     1 
ATOM   2015 C  CD1    . PHE A 1  256 ? 23.13332  -6.76347  40.22212  1.000 28.13602  ? 286 PHE A CD1    1 
ATOM   2016 C  CD2    . PHE A 1  256 ? 22.22665  -7.38949  42.33174  1.000 21.98475  ? 286 PHE A CD2    1 
ATOM   2017 C  CE1    . PHE A 1  256 ? 23.93574  -5.81647  40.84042  1.000 29.67137  ? 286 PHE A CE1    1 
ATOM   2018 C  CE2    . PHE A 1  256 ? 23.04573  -6.42815  42.97012  1.000 22.42798  ? 286 PHE A CE2    1 
ATOM   2019 C  CZ     . PHE A 1  256 ? 23.89215  -5.66472  42.21279  1.000 26.94085  ? 286 PHE A CZ     1 
ATOM   2020 N  N      . ILE A 1  257 ? 19.28684  -8.90174  37.25063  1.000 18.63761  ? 287 ILE A N      1 
ATOM   2021 C  CA     A ILE A 1  257 ? 18.59195  -9.89749  36.43956  0.500 22.08658  ? 287 ILE A CA     1 
ATOM   2022 C  CA     B ILE A 1  257 ? 18.60921  -9.90632  36.44279  0.500 22.08388  ? 287 ILE A CA     1 
ATOM   2023 C  C      . ILE A 1  257 ? 18.91396  -9.63874  34.97411  1.000 23.25156  ? 287 ILE A C      1 
ATOM   2024 O  O      . ILE A 1  257 ? 18.37975  -8.69775  34.37235  1.000 23.66945  ? 287 ILE A O      1 
ATOM   2025 C  CB     A ILE A 1  257 ? 17.07619  -9.86261  36.67516  0.500 21.02218  ? 287 ILE A CB     1 
ATOM   2026 C  CB     B ILE A 1  257 ? 17.10095  -9.92698  36.72448  0.500 21.05833  ? 287 ILE A CB     1 
ATOM   2027 C  CG1    A ILE A 1  257 ? 16.76730  -10.05680 38.16719  0.500 20.60739  ? 287 ILE A CG1    1 
ATOM   2028 C  CG1    B ILE A 1  257 ? 16.88473  -10.48987 38.14504  0.500 20.54869  ? 287 ILE A CG1    1 
ATOM   2029 C  CG2    A ILE A 1  257 ? 16.39269  -10.92063 35.80790  0.500 21.60144  ? 287 ILE A CG2    1 
ATOM   2030 C  CG2    B ILE A 1  257 ? 16.38351  -10.75119 35.65936  0.500 21.45622  ? 287 ILE A CG2    1 
ATOM   2031 C  CD1    A ILE A 1  257 ? 17.19118  -11.40322 38.70934  0.500 19.89407  ? 287 ILE A CD1    1 
ATOM   2032 C  CD1    B ILE A 1  257 ? 15.51773  -10.29052 38.74681  0.500 18.45541  ? 287 ILE A CD1    1 
ATOM   2033 N  N      . LYS A 1  258 ? 19.76370  -10.47824 34.38854  1.000 24.60347  ? 288 LYS A N      1 
ATOM   2034 C  CA     . LYS A 1  258 ? 20.12040  -10.36339 32.97859  1.000 24.23237  ? 288 LYS A CA     1 
ATOM   2035 C  C      . LYS A 1  258 ? 18.99029  -10.85961 32.07876  1.000 24.60685  ? 288 LYS A C      1 
ATOM   2036 O  O      . LYS A 1  258 ? 18.03948  -11.50879 32.52701  1.000 23.72777  ? 288 LYS A O      1 
ATOM   2037 C  CB     . LYS A 1  258 ? 21.41675  -11.12423 32.72632  1.000 24.94721  ? 288 LYS A CB     1 
ATOM   2038 C  CG     . LYS A 1  258 ? 21.23648  -12.64636 32.66085  1.000 23.27205  ? 288 LYS A CG     1 
ATOM   2039 C  CD     . LYS A 1  258 ? 22.58658  -13.33693 32.80861  1.000 26.98792  ? 288 LYS A CD     1 
ATOM   2040 C  CE     . LYS A 1  258 ? 22.49918  -14.85180 32.56358  1.000 26.78536  ? 288 LYS A CE     1 
ATOM   2041 N  NZ     . LYS A 1  258 ? 23.88828  -15.37832 32.31963  1.000 27.83804  ? 288 LYS A NZ     1 
ATOM   2042 N  N      . PRO A 1  259 ? 19.06078  -10.55014 30.77848  1.000 22.43161  ? 289 PRO A N      1 
ATOM   2043 C  CA     . PRO A 1  259 ? 17.93550  -10.86775 29.88460  1.000 20.72804  ? 289 PRO A CA     1 
ATOM   2044 C  C      . PRO A 1  259 ? 17.50727  -12.32660 29.88982  1.000 21.16724  ? 289 PRO A C      1 
ATOM   2045 O  O      . PRO A 1  259 ? 16.31273  -12.62572 30.02466  1.000 24.51322  ? 289 PRO A O      1 
ATOM   2046 C  CB     . PRO A 1  259 ? 18.46768  -10.42277 28.51492  1.000 24.31018  ? 289 PRO A CB     1 
ATOM   2047 C  CG     . PRO A 1  259 ? 19.40856  -9.30080  28.84720  1.000 25.58575  ? 289 PRO A CG     1 
ATOM   2048 C  CD     . PRO A 1  259 ? 20.11550  -9.79196  30.07671  1.000 28.02232  ? 289 PRO A CD     1 
ATOM   2049 N  N      . ARG A 1  260 ? 18.44730  -13.24586 29.69748  1.000 22.83538  ? 290 ARG A N      1 
ATOM   2050 C  CA     . ARG A 1  260 ? 18.09053  -14.66321 29.70995  1.000 25.38467  ? 290 ARG A CA     1 
ATOM   2051 C  C      . ARG A 1  260 ? 17.38860  -15.03821 31.01017  1.000 24.48772  ? 290 ARG A C      1 
ATOM   2052 O  O      . ARG A 1  260 ? 16.38824  -15.76713 31.00662  1.000 23.46616  ? 290 ARG A O      1 
ATOM   2053 C  CB     . ARG A 1  260 ? 19.34677  -15.49828 29.49938  1.000 24.16961  ? 290 ARG A CB     1 
ATOM   2054 C  CG     . ARG A 1  260 ? 19.14693  -16.95216 29.81276  1.000 35.99384  ? 290 ARG A CG     1 
ATOM   2055 C  CD     . ARG A 1  260 ? 18.44903  -17.67352 28.68452  1.000 38.81958  ? 290 ARG A CD     1 
ATOM   2056 N  NE     . ARG A 1  260 ? 16.99105  -17.69526 28.78986  1.000 43.17061  ? 290 ARG A NE     1 
ATOM   2057 C  CZ     . ARG A 1  260 ? 16.15761  -17.37119 27.80495  1.000 43.68644  ? 290 ARG A CZ     1 
ATOM   2058 N  NH1    . ARG A 1  260 ? 16.59183  -16.82846 26.67880  1.000 40.87016  ? 290 ARG A NH1    1 
ATOM   2059 N  NH2    . ARG A 1  260 ? 14.85487  -17.62219 27.94168  1.000 36.97659  ? 290 ARG A NH2    1 
ATOM   2060 N  N      . THR A 1  261 ? 17.91317  -14.55954 32.14146  1.000 20.60868  ? 291 THR A N      1 
ATOM   2061 C  CA     . THR A 1  261 ? 17.28976  -14.84269 33.42698  1.000 21.39429  ? 291 THR A CA     1 
ATOM   2062 C  C      . THR A 1  261 ? 15.89398  -14.24851 33.50580  1.000 22.35913  ? 291 THR A C      1 
ATOM   2063 O  O      . THR A 1  261 ? 14.97239  -14.87851 34.03108  1.000 19.27687  ? 291 THR A O      1 
ATOM   2064 C  CB     . THR A 1  261 ? 18.16577  -14.29594 34.55771  1.000 21.31714  ? 291 THR A CB     1 
ATOM   2065 O  OG1    . THR A 1  261 ? 19.48852  -14.83245 34.42474  1.000 20.65314  ? 291 THR A OG1    1 
ATOM   2066 C  CG2    . THR A 1  261 ? 17.60261  -14.69309 35.92076  1.000 22.92735  ? 291 THR A CG2    1 
ATOM   2067 N  N      . LEU A 1  262 ? 15.73059  -13.00664 33.04100  1.000 18.10780  ? 292 LEU A N      1 
ATOM   2068 C  CA     . LEU A 1  262 ? 14.40956  -12.38449 33.05596  1.000 20.90050  ? 292 LEU A CA     1 
ATOM   2069 C  C      . LEU A 1  262 ? 13.40237  -13.23442 32.29108  1.000 22.43944  ? 292 LEU A C      1 
ATOM   2070 O  O      . LEU A 1  262 ? 12.27325  -13.46898 32.75661  1.000 20.31542  ? 292 LEU A O      1 
ATOM   2071 C  CB     . LEU A 1  262 ? 14.51126  -10.96329 32.46634  1.000 17.34314  ? 292 LEU A CB     1 
ATOM   2072 C  CG     . LEU A 1  262 ? 13.18837  -10.20254 32.26097  1.000 21.73094  ? 292 LEU A CG     1 
ATOM   2073 C  CD1    . LEU A 1  262 ? 12.41071  -10.12400 33.56986  1.000 21.35446  ? 292 LEU A CD1    1 
ATOM   2074 C  CD2    . LEU A 1  262 ? 13.45380  -8.80585  31.70918  1.000 20.52983  ? 292 LEU A CD2    1 
ATOM   2075 N  N      . LEU A 1  263 ? 13.79497  -13.70132 31.10370  1.000 19.27665  ? 293 LEU A N      1 
ATOM   2076 C  CA     . LEU A 1  263 ? 12.91258  -14.55172 30.31171  1.000 22.10847  ? 293 LEU A CA     1 
ATOM   2077 C  C      . LEU A 1  263 ? 12.58373  -15.85279 31.03740  1.000 22.62180  ? 293 LEU A C      1 
ATOM   2078 O  O      . LEU A 1  263 ? 11.41808  -16.27736 31.05515  1.000 23.36199  ? 293 LEU A O      1 
ATOM   2079 C  CB     . LEU A 1  263 ? 13.56328  -14.82018 28.95458  1.000 23.08738  ? 293 LEU A CB     1 
ATOM   2080 C  CG     . LEU A 1  263 ? 13.65265  -13.52903 28.12133  1.000 21.84708  ? 293 LEU A CG     1 
ATOM   2081 C  CD1    . LEU A 1  263 ? 14.65073  -13.68445 26.99267  1.000 29.96809  ? 293 LEU A CD1    1 
ATOM   2082 C  CD2    . LEU A 1  263 ? 12.27618  -13.16666 27.59370  1.000 24.72796  ? 293 LEU A CD2    1 
ATOM   2083 N  N      . ASP A 1  264 ? 13.58954  -16.48080 31.67624  1.000 20.24110  ? 294 ASP A N      1 
ATOM   2084 C  CA     . ASP A 1  264 ? 13.33041  -17.72868 32.41047  1.000 20.12684  ? 294 ASP A CA     1 
ATOM   2085 C  C      . ASP A 1  264 ? 12.38844  -17.49776 33.58441  1.000 19.46356  ? 294 ASP A C      1 
ATOM   2086 O  O      . ASP A 1  264 ? 11.53728  -18.33910 33.87614  1.000 19.67697  ? 294 ASP A O      1 
ATOM   2087 C  CB     . ASP A 1  264 ? 14.61905  -18.34281 32.96215  1.000 19.25854  ? 294 ASP A CB     1 
ATOM   2088 C  CG     . ASP A 1  264 ? 15.58529  -18.77387 31.88382  1.000 22.89211  ? 294 ASP A CG     1 
ATOM   2089 O  OD1    . ASP A 1  264 ? 15.18008  -18.88244 30.72337  1.000 21.55209  ? 294 ASP A OD1    1 
ATOM   2090 O  OD2    . ASP A 1  264 ? 16.74723  -19.03333 32.23772  1.000 23.32424  ? 294 ASP A OD2    1 
ATOM   2091 N  N      . TYR A 1  265 ? 12.57223  -16.38942 34.31929  1.000 18.56021  ? 295 TYR A N      1 
ATOM   2092 C  CA     . TYR A 1  265 ? 11.69688  -16.09627 35.45392  1.000 18.69903  ? 295 TYR A CA     1 
ATOM   2093 C  C      . TYR A 1  265 ? 10.27405  -15.83361 34.99121  1.000 16.96129  ? 295 TYR A C      1 
ATOM   2094 O  O      . TYR A 1  265 ? 9.29999   -16.26646 35.63432  1.000 20.79257  ? 295 TYR A O      1 
ATOM   2095 C  CB     . TYR A 1  265 ? 12.20238  -14.88104 36.23737  1.000 17.88919  ? 295 TYR A CB     1 
ATOM   2096 C  CG     . TYR A 1  265 ? 13.45925  -15.07002 37.06341  1.000 17.45990  ? 295 TYR A CG     1 
ATOM   2097 C  CD1    . TYR A 1  265 ? 14.13637  -16.27187 37.10222  1.000 18.03069  ? 295 TYR A CD1    1 
ATOM   2098 C  CD2    . TYR A 1  265 ? 13.97009  -14.00199 37.79999  1.000 18.04788  ? 295 TYR A CD2    1 
ATOM   2099 C  CE1    . TYR A 1  265 ? 15.30252  -16.41170 37.87201  1.000 21.65312  ? 295 TYR A CE1    1 
ATOM   2100 C  CE2    . TYR A 1  265 ? 15.11704  -14.11957 38.55369  1.000 21.94727  ? 295 TYR A CE2    1 
ATOM   2101 C  CZ     . TYR A 1  265 ? 15.78386  -15.32550 38.59139  1.000 20.70366  ? 295 TYR A CZ     1 
ATOM   2102 O  OH     . TYR A 1  265 ? 16.93167  -15.43311 39.36324  1.000 22.19310  ? 295 TYR A OH     1 
ATOM   2103 N  N      . TRP A 1  266 ? 10.13155  -15.09083 33.89385  1.000 19.61452  ? 296 TRP A N      1 
ATOM   2104 C  CA     . TRP A 1  266 ? 8.80364   -14.82008 33.37184  1.000 21.96717  ? 296 TRP A CA     1 
ATOM   2105 C  C      . TRP A 1  266 ? 8.11574   -16.11658 32.96460  1.000 20.40717  ? 296 TRP A C      1 
ATOM   2106 O  O      . TRP A 1  266 ? 6.93862   -16.32918 33.28117  1.000 21.52428  ? 296 TRP A O      1 
ATOM   2107 C  CB     . TRP A 1  266 ? 8.89770   -13.84455 32.19440  1.000 24.15974  ? 296 TRP A CB     1 
ATOM   2108 C  CG     . TRP A 1  266 ? 7.60213   -13.16763 31.89543  1.000 23.76903  ? 296 TRP A CG     1 
ATOM   2109 C  CD1    . TRP A 1  266 ? 6.77369   -13.40859 30.83726  1.000 25.45801  ? 296 TRP A CD1    1 
ATOM   2110 C  CD2    . TRP A 1  266 ? 6.99035   -12.13323 32.66277  1.000 27.65732  ? 296 TRP A CD2    1 
ATOM   2111 N  NE1    . TRP A 1  266 ? 5.68156   -12.59312 30.90523  1.000 29.22565  ? 296 TRP A NE1    1 
ATOM   2112 C  CE2    . TRP A 1  266 ? 5.78606   -11.79702 32.01739  1.000 28.30130  ? 296 TRP A CE2    1 
ATOM   2113 C  CE3    . TRP A 1  266 ? 7.34178   -11.46106 33.83889  1.000 24.51063  ? 296 TRP A CE3    1 
ATOM   2114 C  CZ2    . TRP A 1  266 ? 4.93167   -10.80465 32.49884  1.000 26.43583  ? 296 TRP A CZ2    1 
ATOM   2115 C  CZ3    . TRP A 1  266 ? 6.48911   -10.47217 34.31721  1.000 28.78798  ? 296 TRP A CZ3    1 
ATOM   2116 C  CH2    . TRP A 1  266 ? 5.30045   -10.15725 33.64222  1.000 25.48429  ? 296 TRP A CH2    1 
ATOM   2117 N  N      . GLN A 1  267 ? 8.84661   -17.00171 32.28040  1.000 22.42698  ? 297 GLN A N      1 
ATOM   2118 C  CA     . GLN A 1  267 ? 8.29915   -18.31566 31.93410  1.000 23.35508  ? 297 GLN A CA     1 
ATOM   2119 C  C      . GLN A 1  267 ? 7.90075   -19.09236 33.18259  1.000 24.18622  ? 297 GLN A C      1 
ATOM   2120 O  O      . GLN A 1  267 ? 6.85938   -19.76796 33.19950  1.000 25.18228  ? 297 GLN A O      1 
ATOM   2121 C  CB     . GLN A 1  267 ? 9.31615   -19.10808 31.11494  1.000 22.72956  ? 297 GLN A CB     1 
ATOM   2122 C  CG     . GLN A 1  267 ? 8.78628   -20.41606 30.50143  1.000 35.01242  ? 297 GLN A CG     1 
ATOM   2123 C  CD     . GLN A 1  267 ? 7.63171   -20.17571 29.55801  1.000 44.02024  ? 297 GLN A CD     1 
ATOM   2124 O  OE1    . GLN A 1  267 ? 7.79659   -19.55122 28.50744  1.000 57.59453  ? 297 GLN A OE1    1 
ATOM   2125 N  NE2    . GLN A 1  267 ? 6.45097   -20.66453 29.92775  1.000 47.06841  ? 297 GLN A NE2    1 
ATOM   2126 N  N      . ALA A 1  268 ? 8.73008   -19.03970 34.22915  1.000 19.64927  ? 298 ALA A N      1 
ATOM   2127 C  CA     . ALA A 1  268 ? 8.39885   -19.72741 35.47490  1.000 18.78451  ? 298 ALA A CA     1 
ATOM   2128 C  C      . ALA A 1  268 ? 7.06841   -19.24259 36.03162  1.000 23.59718  ? 298 ALA A C      1 
ATOM   2129 O  O      . ALA A 1  268 ? 6.25126   -20.03828 36.50775  1.000 21.16059  ? 298 ALA A O      1 
ATOM   2130 C  CB     . ALA A 1  268 ? 9.48925   -19.49758 36.50995  1.000 18.89659  ? 298 ALA A CB     1 
ATOM   2131 N  N      . LEU A 1  269 ? 6.87485   -17.92531 36.05866  1.000 23.74984  ? 299 LEU A N      1 
ATOM   2132 C  CA     . LEU A 1  269 ? 5.63775   -17.38909 36.60812  1.000 23.92222  ? 299 LEU A CA     1 
ATOM   2133 C  C      . LEU A 1  269 ? 4.45043   -17.76839 35.72857  1.000 20.96041  ? 299 LEU A C      1 
ATOM   2134 O  O      . LEU A 1  269 ? 3.37104   -18.07585 36.24071  1.000 30.45108  ? 299 LEU A O      1 
ATOM   2135 C  CB     . LEU A 1  269 ? 5.74915   -15.86477 36.78008  1.000 22.51964  ? 299 LEU A CB     1 
ATOM   2136 C  CG     . LEU A 1  269 ? 6.81461   -15.48568 37.83208  1.000 21.32103  ? 299 LEU A CG     1 
ATOM   2137 C  CD1    . LEU A 1  269 ? 7.28148   -14.03797 37.70329  1.000 26.99471  ? 299 LEU A CD1    1 
ATOM   2138 C  CD2    . LEU A 1  269 ? 6.34010   -15.78906 39.24417  1.000 26.46076  ? 299 LEU A CD2    1 
ATOM   2139 N  N      . GLU A 1  270 ? 4.62870   -17.76800 34.40525  1.000 25.88996  ? 300 GLU A N      1 
ATOM   2140 C  CA     . GLU A 1  270 ? 3.55701   -18.26334 33.54081  1.000 28.06232  ? 300 GLU A CA     1 
ATOM   2141 C  C      . GLU A 1  270 ? 3.27446   -19.74057 33.80703  1.000 35.96584  ? 300 GLU A C      1 
ATOM   2142 O  O      . GLU A 1  270 ? 2.11219   -20.14942 33.90592  1.000 31.55426  ? 300 GLU A O      1 
ATOM   2143 C  CB     . GLU A 1  270 ? 3.89306   -18.03811 32.06707  1.000 31.62035  ? 300 GLU A CB     1 
ATOM   2144 C  CG     . GLU A 1  270 ? 3.63228   -16.62075 31.58750  1.000 46.88670  ? 300 GLU A CG     1 
ATOM   2145 C  CD     . GLU A 1  270 ? 2.14761   -16.27370 31.61331  1.000 62.21888  ? 300 GLU A CD     1 
ATOM   2146 O  OE1    . GLU A 1  270 ? 1.31106   -17.20513 31.50305  1.000 60.09322  ? 300 GLU A OE1    1 
ATOM   2147 O  OE2    . GLU A 1  270 ? 1.82255   -15.07650 31.76560  1.000 69.09423  ? 300 GLU A OE2    1 
ATOM   2148 N  N      . ASN A 1  271 ? 4.32666   -20.56342 33.89747  1.000 27.56918  ? 301 ASN A N      1 
ATOM   2149 C  CA     . ASN A 1  271 ? 4.12831   -22.00668 34.07901  1.000 24.36316  ? 301 ASN A CA     1 
ATOM   2150 C  C      . ASN A 1  271 ? 3.37490   -22.33290 35.35893  1.000 30.43185  ? 301 ASN A C      1 
ATOM   2151 O  O      . ASN A 1  271 ? 2.66297   -23.33777 35.41378  1.000 31.80808  ? 301 ASN A O      1 
ATOM   2152 C  CB     . ASN A 1  271 ? 5.46937   -22.74918 34.09193  1.000 27.24609  ? 301 ASN A CB     1 
ATOM   2153 C  CG     . ASN A 1  271 ? 6.16358   -22.73697 32.74486  1.000 35.00658  ? 301 ASN A CG     1 
ATOM   2154 O  OD1    . ASN A 1  271 ? 5.56829   -22.36397 31.73699  1.000 40.47596  ? 301 ASN A OD1    1 
ATOM   2155 N  ND2    . ASN A 1  271 ? 7.43166   -23.17920 32.71424  1.000 34.34547  ? 301 ASN A ND2    1 
ATOM   2156 N  N      . SER A 1  272 ? 3.54589   -21.53564 36.40782  1.000 23.99809  ? 302 SER A N      1 
ATOM   2157 C  CA     . SER A 1  272 ? 2.98102   -21.82142 37.72107  1.000 28.35316  ? 302 SER A CA     1 
ATOM   2158 C  C      . SER A 1  272 ? 1.72226   -21.01825 38.01182  1.000 29.87893  ? 302 SER A C      1 
ATOM   2159 O  O      . SER A 1  272 ? 1.20042   -21.07517 39.12737  1.000 28.22749  ? 302 SER A O      1 
ATOM   2160 C  CB     . SER A 1  272 ? 4.03625   -21.56268 38.80386  1.000 27.01328  ? 302 SER A CB     1 
ATOM   2161 O  OG     . SER A 1  272 ? 4.56465   -20.26560 38.61372  1.000 31.18594  ? 302 SER A OG     1 
ATOM   2162 N  N      . ARG A 1  273 ? 1.26650   -20.22411 37.05797  1.000 32.01416  ? 303 ARG A N      1 
ATOM   2163 C  CA     . ARG A 1  273 ? -0.01085  -19.54796 37.18637  1.000 39.33083  ? 303 ARG A CA     1 
ATOM   2164 C  C      . ARG A 1  273 ? -1.09813  -20.56330 37.50151  1.000 47.47120  ? 303 ARG A C      1 
ATOM   2165 O  O      . ARG A 1  273 ? -1.19022  -21.61500 36.86362  1.000 46.59148  ? 303 ARG A O      1 
ATOM   2166 C  CB     . ARG A 1  273 ? -0.30231  -18.80353 35.88509  1.000 40.11781  ? 303 ARG A CB     1 
ATOM   2167 C  CG     . ARG A 1  273 ? -1.64784  -18.13247 35.78616  1.000 58.44803  ? 303 ARG A CG     1 
ATOM   2168 C  CD     . ARG A 1  273 ? -1.81030  -17.57775 34.37005  1.000 59.05037  ? 303 ARG A CD     1 
ATOM   2169 N  NE     . ARG A 1  273 ? -1.07958  -18.37038 33.38104  1.000 59.03168  ? 303 ARG A NE     1 
ATOM   2170 C  CZ     . ARG A 1  273 ? -1.49845  -19.49331 32.80866  1.000 65.48096  ? 303 ARG A CZ     1 
ATOM   2171 N  NH1    . ARG A 1  273 ? -2.71122  -19.97612 33.02667  1.000 68.76326  ? 303 ARG A NH1    1 
ATOM   2172 N  NH2    . ARG A 1  273 ? -0.68670  -20.13389 31.96943  1.000 65.58154  ? 303 ARG A NH2    1 
ATOM   2173 N  N      . GLY A 1  274 ? -1.88006  -20.28413 38.52925  1.000 53.61453  ? 304 GLY A N      1 
ATOM   2174 C  CA     . GLY A 1  274 ? -2.92002  -21.20517 38.92557  1.000 52.52382  ? 304 GLY A CA     1 
ATOM   2175 C  C      . GLY A 1  274 ? -2.53707  -22.10848 40.06936  1.000 55.37189  ? 304 GLY A C      1 
ATOM   2176 O  O      . GLY A 1  274 ? -3.40081  -22.82942 40.58578  1.000 52.41321  ? 304 GLY A O      1 
ATOM   2177 N  N      . GLU A 1  275 ? -1.27286  -22.11003 40.47280  1.000 37.05171  ? 305 GLU A N      1 
ATOM   2178 C  CA     . GLU A 1  275 ? -0.95549  -22.76712 41.72136  1.000 33.99415  ? 305 GLU A CA     1 
ATOM   2179 C  C      . GLU A 1  275 ? -1.07933  -21.77681 42.86239  1.000 45.73355  ? 305 GLU A C      1 
ATOM   2180 O  O      . GLU A 1  275 ? -1.05031  -20.56249 42.66679  1.000 45.52157  ? 305 GLU A O      1 
ATOM   2181 C  CB     . GLU A 1  275 ? 0.44045   -23.36078 41.69295  1.000 40.65595  ? 305 GLU A CB     1 
ATOM   2182 C  CG     . GLU A 1  275 ? 0.70772   -24.23062 40.50005  1.000 42.88951  ? 305 GLU A CG     1 
ATOM   2183 C  CD     . GLU A 1  275 ? 1.59440   -25.36395 40.89460  1.000 38.79172  ? 305 GLU A CD     1 
ATOM   2184 O  OE1    . GLU A 1  275 ? 2.24296   -25.21624 41.95630  1.000 38.97862  ? 305 GLU A OE1    1 
ATOM   2185 O  OE2    . GLU A 1  275 ? 1.63461   -26.38945 40.17382  1.000 44.47447  ? 305 GLU A OE2    1 
ATOM   2186 N  N      . ASP A 1  276 ? -1.20597  -22.32023 44.06408  1.000 45.05587  ? 306 ASP A N      1 
ATOM   2187 C  CA     . ASP A 1  276 ? -1.30358  -21.56320 45.30106  1.000 58.58354  ? 306 ASP A CA     1 
ATOM   2188 C  C      . ASP A 1  276 ? 0.05190   -21.58573 46.00850  1.000 55.99321  ? 306 ASP A C      1 
ATOM   2189 O  O      . ASP A 1  276 ? 0.95688   -22.32947 45.62537  1.000 52.95798  ? 306 ASP A O      1 
ATOM   2190 C  CB     . ASP A 1  276 ? -2.42131  -22.15093 46.16932  1.000 71.95413  ? 306 ASP A CB     1 
ATOM   2191 C  CG     . ASP A 1  276 ? -3.78728  -22.09213 45.47942  1.000 79.34450  ? 306 ASP A CG     1 
ATOM   2192 O  OD1    . ASP A 1  276 ? -3.97546  -21.22689 44.59449  1.000 78.65665  ? 306 ASP A OD1    1 
ATOM   2193 O  OD2    . ASP A 1  276 ? -4.65420  -22.94068 45.78354  1.000 80.64544  ? 306 ASP A OD2    1 
ATOM   2194 N  N      . CYS A 1  277 ? 0.18200   -20.79776 47.08400  1.000 61.23772  ? 307 CYS A N      1 
ATOM   2195 C  CA     . CYS A 1  277 ? 1.51602   -20.65061 47.66819  1.000 62.28555  ? 307 CYS A CA     1 
ATOM   2196 C  C      . CYS A 1  277 ? 1.56256   -20.69636 49.19593  1.000 69.20912  ? 307 CYS A C      1 
ATOM   2197 O  O      . CYS A 1  277 ? 2.13449   -21.64152 49.75634  1.000 68.55711  ? 307 CYS A O      1 
ATOM   2198 C  CB     . CYS A 1  277 ? 2.16675   -19.33297 47.20646  1.000 61.62978  ? 307 CYS A CB     1 
ATOM   2199 S  SG     . CYS A 1  277 ? 2.97678   -19.29743 45.57134  1.000 41.31665  ? 307 CYS A SG     1 
ATOM   2200 N  N      . PRO A 1  278 ? 1.00850   -19.70504 49.91347  1.000 78.22971  ? 308 PRO A N      1 
ATOM   2201 C  CA     . PRO A 1  278 ? 1.25682   -19.69304 51.36218  1.000 75.91141  ? 308 PRO A CA     1 
ATOM   2202 C  C      . PRO A 1  278 ? 0.70026   -20.91548 52.07570  1.000 82.39714  ? 308 PRO A C      1 
ATOM   2203 O  O      . PRO A 1  278 ? 0.27520   -20.76446 53.22010  1.000 93.17215  ? 308 PRO A O      1 
ATOM   2204 C  CB     . PRO A 1  278 ? 0.54023   -18.42153 51.83871  1.000 83.17927  ? 308 PRO A CB     1 
ATOM   2205 C  CG     . PRO A 1  278 ? 0.35263   -17.58923 50.60794  1.000 82.37356  ? 308 PRO A CG     1 
ATOM   2206 C  CD     . PRO A 1  278 ? 0.17570   -18.56848 49.48433  1.000 82.11635  ? 308 PRO A CD     1 
ATOM   2207 N  N      . ASN B 1  13  ? 19.94467  29.08328  -8.89379  1.000 73.46494  ? 43  ASN B N      1 
ATOM   2208 C  CA     . ASN B 1  13  ? 19.15432  27.98431  -9.44673  1.000 64.35718  ? 43  ASN B CA     1 
ATOM   2209 C  C      . ASN B 1  13  ? 19.59180  26.56939  -9.10059  1.000 73.44250  ? 43  ASN B C      1 
ATOM   2210 O  O      . ASN B 1  13  ? 19.78767  26.20654  -7.93887  1.000 74.72320  ? 43  ASN B O      1 
ATOM   2211 C  CB     . ASN B 1  13  ? 19.09121  28.07965  -10.97604 1.000 67.91346  ? 43  ASN B CB     1 
ATOM   2212 C  CG     . ASN B 1  13  ? 18.10289  29.11852  -11.45867 1.000 83.87052  ? 43  ASN B CG     1 
ATOM   2213 O  OD1    . ASN B 1  13  ? 17.21035  29.52846  -10.71612 1.000 85.81119  ? 43  ASN B OD1    1 
ATOM   2214 N  ND2    . ASN B 1  13  ? 18.23173  29.52477  -12.71888 1.000 80.17010  ? 43  ASN B ND2    1 
ATOM   2215 N  N      . PHE B 1  14  ? 19.71382  25.77631  -10.15785 1.000 65.29664  ? 44  PHE B N      1 
ATOM   2216 C  CA     . PHE B 1  14  ? 19.86461  24.33617  -10.05892 1.000 68.37391  ? 44  PHE B CA     1 
ATOM   2217 C  C      . PHE B 1  14  ? 21.32532  23.90738  -10.01038 1.000 70.40919  ? 44  PHE B C      1 
ATOM   2218 O  O      . PHE B 1  14  ? 22.16559  24.41598  -10.75716 1.000 70.60268  ? 44  PHE B O      1 
ATOM   2219 C  CB     . PHE B 1  14  ? 19.14066  23.68733  -11.23400 1.000 60.11348  ? 44  PHE B CB     1 
ATOM   2220 C  CG     . PHE B 1  14  ? 17.64469  23.84937  -11.16793 1.000 62.17436  ? 44  PHE B CG     1 
ATOM   2221 C  CD1    . PHE B 1  14  ? 17.04460  25.00544  -11.63701 1.000 65.02965  ? 44  PHE B CD1    1 
ATOM   2222 C  CD2    . PHE B 1  14  ? 16.84247  22.85922  -10.62465 1.000 63.13984  ? 44  PHE B CD2    1 
ATOM   2223 C  CE1    . PHE B 1  14  ? 15.67085  25.16948  -11.57876 1.000 69.89472  ? 44  PHE B CE1    1 
ATOM   2224 C  CE2    . PHE B 1  14  ? 15.46615  23.01707  -10.56280 1.000 63.08785  ? 44  PHE B CE2    1 
ATOM   2225 C  CZ     . PHE B 1  14  ? 14.88166  24.17381  -11.04350 1.000 62.13698  ? 44  PHE B CZ     1 
ATOM   2226 N  N      . LEU B 1  15  ? 21.61717  22.97164  -9.10393  1.000 74.00252  ? 45  LEU B N      1 
ATOM   2227 C  CA     . LEU B 1  15  ? 22.95848  22.41129  -8.96606  1.000 72.01605  ? 45  LEU B CA     1 
ATOM   2228 C  C      . LEU B 1  15  ? 23.21544  21.29561  -9.97457  1.000 73.14973  ? 45  LEU B C      1 
ATOM   2229 O  O      . LEU B 1  15  ? 24.34079  21.14243  -10.46126 1.000 72.93497  ? 45  LEU B O      1 
ATOM   2230 C  CB     . LEU B 1  15  ? 23.15387  21.89535  -7.54062  1.000 73.92393  ? 45  LEU B CB     1 
ATOM   2231 C  CG     . LEU B 1  15  ? 22.62199  22.82317  -6.43946  1.000 82.09666  ? 45  LEU B CG     1 
ATOM   2232 C  CD1    . LEU B 1  15  ? 23.04703  22.32933  -5.06032  1.000 81.65504  ? 45  LEU B CD1    1 
ATOM   2233 C  CD2    . LEU B 1  15  ? 23.02027  24.29183  -6.66082  1.000 72.26432  ? 45  LEU B CD2    1 
ATOM   2234 N  N      . LYS B 1  16  ? 22.20106  20.48547  -10.26872 1.000 73.08583  ? 46  LYS B N      1 
ATOM   2235 C  CA     . LYS B 1  16  ? 22.27686  19.47192  -11.31139 1.000 72.35721  ? 46  LYS B CA     1 
ATOM   2236 C  C      . LYS B 1  16  ? 21.01434  19.56511  -12.15220 1.000 64.19749  ? 46  LYS B C      1 
ATOM   2237 O  O      . LYS B 1  16  ? 19.91134  19.66864  -11.60761 1.000 63.04767  ? 46  LYS B O      1 
ATOM   2238 C  CB     . LYS B 1  16  ? 22.42053  18.05465  -10.73816 1.000 75.19728  ? 46  LYS B CB     1 
ATOM   2239 C  CG     . LYS B 1  16  ? 23.70439  17.77023  -9.96419  1.000 72.09247  ? 46  LYS B CG     1 
ATOM   2240 C  CD     . LYS B 1  16  ? 23.73732  16.29987  -9.55277  1.000 78.75747  ? 46  LYS B CD     1 
ATOM   2241 C  CE     . LYS B 1  16  ? 25.06981  15.87629  -8.94790  1.000 82.92748  ? 46  LYS B CE     1 
ATOM   2242 N  NZ     . LYS B 1  16  ? 25.38150  16.61039  -7.69305  1.000 86.19556  ? 46  LYS B NZ     1 
ATOM   2243 N  N      . LEU B 1  17  ? 21.17407  19.53083  -13.47296 1.000 73.11351  ? 47  LEU B N      1 
ATOM   2244 C  CA     . LEU B 1  17  ? 20.04655  19.56140  -14.39541 1.000 71.12124  ? 47  LEU B CA     1 
ATOM   2245 C  C      . LEU B 1  17  ? 20.13051  18.37977  -15.35220 1.000 76.24019  ? 47  LEU B C      1 
ATOM   2246 O  O      . LEU B 1  17  ? 21.20481  18.11810  -15.92435 1.000 73.92539  ? 47  LEU B O      1 
ATOM   2247 C  CB     . LEU B 1  17  ? 19.98858  20.87002  -15.19881 1.000 65.09992  ? 47  LEU B CB     1 
ATOM   2248 C  CG     . LEU B 1  17  ? 19.33824  22.08329  -14.54771 1.000 62.94665  ? 47  LEU B CG     1 
ATOM   2249 C  CD1    . LEU B 1  17  ? 19.39583  23.27422  -15.47962 1.000 60.61569  ? 47  LEU B CD1    1 
ATOM   2250 C  CD2    . LEU B 1  17  ? 17.89440  21.74193  -14.23574 1.000 69.01678  ? 47  LEU B CD2    1 
ATOM   2251 N  N      . PRO B 1  18  ? 19.04075  17.64123  -15.54792 1.000 74.10337  ? 48  PRO B N      1 
ATOM   2252 C  CA     . PRO B 1  18  ? 19.05064  16.59985  -16.57525 1.000 76.09369  ? 48  PRO B CA     1 
ATOM   2253 C  C      . PRO B 1  18  ? 19.23051  17.24436  -17.93946 1.000 77.84450  ? 48  PRO B C      1 
ATOM   2254 O  O      . PRO B 1  18  ? 18.72771  18.33929  -18.20769 1.000 74.37648  ? 48  PRO B O      1 
ATOM   2255 C  CB     . PRO B 1  18  ? 17.67883  15.93199  -16.42657 1.000 75.68371  ? 48  PRO B CB     1 
ATOM   2256 C  CG     . PRO B 1  18  ? 16.81999  16.97127  -15.77510 1.000 74.13184  ? 48  PRO B CG     1 
ATOM   2257 C  CD     . PRO B 1  18  ? 17.74063  17.73480  -14.86212 1.000 75.73353  ? 48  PRO B CD     1 
ATOM   2258 N  N      . ASP B 1  19  ? 19.97490  16.55712  -18.79232 1.000 75.21776  ? 49  ASP B N      1 
ATOM   2259 C  CA     . ASP B 1  19  ? 20.32544  17.04008  -20.12376 1.000 77.21174  ? 49  ASP B CA     1 
ATOM   2260 C  C      . ASP B 1  19  ? 19.14996  16.76098  -21.06046 1.000 73.34842  ? 49  ASP B C      1 
ATOM   2261 O  O      . ASP B 1  19  ? 19.08683  15.72380  -21.72331 1.000 72.42685  ? 49  ASP B O      1 
ATOM   2262 C  CB     . ASP B 1  19  ? 21.61821  16.37493  -20.57768 1.000 80.29324  ? 49  ASP B CB     1 
ATOM   2263 C  CG     . ASP B 1  19  ? 22.23163  17.04218  -21.77755 1.000 77.34799  ? 49  ASP B CG     1 
ATOM   2264 O  OD1    . ASP B 1  19  ? 21.57608  17.91833  -22.37991 1.000 76.29573  ? 49  ASP B OD1    1 
ATOM   2265 O  OD2    . ASP B 1  19  ? 23.39440  16.70651  -22.09013 1.000 75.00576  ? 49  ASP B OD2    1 
ATOM   2266 N  N      . THR B 1  20  ? 18.19307  17.69021  -21.10570 1.000 68.30758  ? 50  THR B N      1 
ATOM   2267 C  CA     . THR B 1  20  ? 16.96057  17.49209  -21.85713 1.000 72.81882  ? 50  THR B CA     1 
ATOM   2268 C  C      . THR B 1  20  ? 16.52633  18.77132  -22.55786 1.000 76.62505  ? 50  THR B C      1 
ATOM   2269 O  O      . THR B 1  20  ? 16.84263  19.88189  -22.12220 1.000 71.09793  ? 50  THR B O      1 
ATOM   2270 C  CB     . THR B 1  20  ? 15.81365  17.03720  -20.94915 1.000 77.90789  ? 50  THR B CB     1 
ATOM   2271 O  OG1    . THR B 1  20  ? 14.74143  16.52866  -21.75317 1.000 80.18690  ? 50  THR B OG1    1 
ATOM   2272 C  CG2    . THR B 1  20  ? 15.30494  18.21117  -20.11683 1.000 78.10017  ? 50  THR B CG2    1 
ATOM   2273 N  N      . ASP B 1  21  ? 15.81114  18.59472  -23.67159 1.000 76.28896  ? 51  ASP B N      1 
ATOM   2274 C  CA     . ASP B 1  21  ? 15.29377  19.69890  -24.48072 1.000 78.65839  ? 51  ASP B CA     1 
ATOM   2275 C  C      . ASP B 1  21  ? 13.83085  19.37806  -24.78217 1.000 75.01056  ? 51  ASP B C      1 
ATOM   2276 O  O      . ASP B 1  21  ? 13.52008  18.72184  -25.78117 1.000 76.28175  ? 51  ASP B O      1 
ATOM   2277 C  CB     . ASP B 1  21  ? 16.11232  19.88933  -25.75385 1.000 81.10654  ? 51  ASP B CB     1 
ATOM   2278 C  CG     . ASP B 1  21  ? 15.73270  21.15024  -26.51130 1.000 82.49060  ? 51  ASP B CG     1 
ATOM   2279 O  OD1    . ASP B 1  21  ? 14.52504  21.46022  -26.60943 1.000 77.55412  ? 51  ASP B OD1    1 
ATOM   2280 O  OD2    . ASP B 1  21  ? 16.65184  21.83403  -27.01138 1.000 93.98326  ? 51  ASP B OD2    1 
ATOM   2281 N  N      . CYS B 1  22  ? 12.93396  19.83565  -23.90549 1.000 73.25114  ? 52  CYS B N      1 
ATOM   2282 C  CA     . CYS B 1  22  ? 11.51391  19.54846  -24.07010 1.000 71.92054  ? 52  CYS B CA     1 
ATOM   2283 C  C      . CYS B 1  22  ? 10.88375  20.33765  -25.21153 1.000 69.06870  ? 52  CYS B C      1 
ATOM   2284 O  O      . CYS B 1  22  ? 9.80755   19.95852  -25.68533 1.000 67.74229  ? 52  CYS B O      1 
ATOM   2285 C  CB     . CYS B 1  22  ? 10.75510  19.81846  -22.76591 1.000 65.44470  ? 52  CYS B CB     1 
ATOM   2286 S  SG     . CYS B 1  22  ? 11.16430  18.74248  -21.34228 1.000 63.65005  ? 52  CYS B SG     1 
ATOM   2287 N  N      . ARG B 1  23  ? 11.52020  21.42141  -25.66306 1.000 73.18995  ? 53  ARG B N      1 
ATOM   2288 C  CA     . ARG B 1  23  ? 10.97435  22.18356  -26.78328 1.000 74.74745  ? 53  ARG B CA     1 
ATOM   2289 C  C      . ARG B 1  23  ? 11.02884  21.38003  -28.07823 1.000 78.27385  ? 53  ARG B C      1 
ATOM   2290 O  O      . ARG B 1  23  ? 10.04131  21.31877  -28.82113 1.000 72.31775  ? 53  ARG B O      1 
ATOM   2291 C  CB     . ARG B 1  23  ? 11.72995  23.50103  -26.93073 1.000 79.87469  ? 53  ARG B CB     1 
ATOM   2292 C  CG     . ARG B 1  23  ? 11.05588  24.50927  -27.83833 1.000 83.08715  ? 53  ARG B CG     1 
ATOM   2293 C  CD     . ARG B 1  23  ? 11.30614  25.91079  -27.32155 1.000 93.51926  ? 53  ARG B CD     1 
ATOM   2294 N  NE     . ARG B 1  23  ? 12.73300  26.17608  -27.17679 1.000 105.21950 ? 53  ARG B NE     1 
ATOM   2295 C  CZ     . ARG B 1  23  ? 13.24355  27.16476  -26.45504 1.000 101.21634 ? 53  ARG B CZ     1 
ATOM   2296 N  NH1    . ARG B 1  23  ? 12.46889  28.01029  -25.79442 1.000 98.63222  ? 53  ARG B NH1    1 
ATOM   2297 N  NH2    . ARG B 1  23  ? 14.56488  27.30505  -26.38965 1.000 94.96205  ? 53  ARG B NH2    1 
ATOM   2298 N  N      . GLN B 1  24  ? 12.18230  20.76788  -28.37340 1.000 77.64913  ? 54  GLN B N      1 
ATOM   2299 C  CA     . GLN B 1  24  ? 12.28248  19.88705  -29.53563 1.000 78.70635  ? 54  GLN B CA     1 
ATOM   2300 C  C      . GLN B 1  24  ? 11.40467  18.65303  -29.37246 1.000 80.07797  ? 54  GLN B C      1 
ATOM   2301 O  O      . GLN B 1  24  ? 10.62915  18.30829  -30.27262 1.000 82.36551  ? 54  GLN B O      1 
ATOM   2302 C  CB     . GLN B 1  24  ? 13.73752  19.48626  -29.79535 1.000 80.94020  ? 54  GLN B CB     1 
ATOM   2303 C  CG     . GLN B 1  24  ? 13.90403  18.56332  -31.01366 1.000 89.95078  ? 54  GLN B CG     1 
ATOM   2304 C  CD     . GLN B 1  24  ? 13.91616  19.28851  -32.35626 1.000 81.18093  ? 54  GLN B CD     1 
ATOM   2305 O  OE1    . GLN B 1  24  ? 14.25267  20.47151  -32.44343 1.000 76.27922  ? 54  GLN B OE1    1 
ATOM   2306 N  NE2    . GLN B 1  24  ? 13.52949  18.57225  -33.41327 1.000 73.30669  ? 54  GLN B NE2    1 
ATOM   2307 N  N      . THR B 1  25  ? 11.51027  17.96945  -28.23023 1.000 76.22900  ? 55  THR B N      1 
ATOM   2308 C  CA     . THR B 1  25  ? 10.76460  16.73890  -27.97916 1.000 75.17841  ? 55  THR B CA     1 
ATOM   2309 C  C      . THR B 1  25  ? 9.89764   16.94722  -26.74290 1.000 71.88838  ? 55  THR B C      1 
ATOM   2310 O  O      . THR B 1  25  ? 10.28800  16.57602  -25.62559 1.000 72.04931  ? 55  THR B O      1 
ATOM   2311 C  CB     . THR B 1  25  ? 11.69827  15.54301  -27.79261 1.000 80.63140  ? 55  THR B CB     1 
ATOM   2312 O  OG1    . THR B 1  25  ? 12.66396  15.51681  -28.85122 1.000 80.48791  ? 55  THR B OG1    1 
ATOM   2313 C  CG2    . THR B 1  25  ? 10.90353  14.23439  -27.79540 1.000 73.51937  ? 55  THR B CG2    1 
ATOM   2314 N  N      . PRO B 1  26  ? 8.72483   17.55309  -26.90043 1.000 67.09001  ? 56  PRO B N      1 
ATOM   2315 C  CA     . PRO B 1  26  ? 7.81215   17.70070  -25.77171 1.000 65.29323  ? 56  PRO B CA     1 
ATOM   2316 C  C      . PRO B 1  26  ? 7.39661   16.34148  -25.24038 1.000 67.84540  ? 56  PRO B C      1 
ATOM   2317 O  O      . PRO B 1  26  ? 6.86164   15.50508  -25.98727 1.000 61.56932  ? 56  PRO B O      1 
ATOM   2318 C  CB     . PRO B 1  26  ? 6.61787   18.45529  -26.37516 1.000 62.62556  ? 56  PRO B CB     1 
ATOM   2319 C  CG     . PRO B 1  26  ? 6.70658   18.19278  -27.84427 1.000 69.35678  ? 56  PRO B CG     1 
ATOM   2320 C  CD     . PRO B 1  26  ? 8.17340   18.13549  -28.13358 1.000 69.29204  ? 56  PRO B CD     1 
ATOM   2321 N  N      . PRO B 1  27  ? 7.63323   16.07544  -23.95945 1.000 61.86582  ? 57  PRO B N      1 
ATOM   2322 C  CA     . PRO B 1  27  ? 7.19399   14.80004  -23.38827 1.000 52.36271  ? 57  PRO B CA     1 
ATOM   2323 C  C      . PRO B 1  27  ? 5.69005   14.78887  -23.16434 1.000 54.97388  ? 57  PRO B C      1 
ATOM   2324 O  O      . PRO B 1  27  ? 5.06124   15.82587  -22.92721 1.000 52.00622  ? 57  PRO B O      1 
ATOM   2325 C  CB     . PRO B 1  27  ? 7.96152   14.71716  -22.06313 1.000 57.74223  ? 57  PRO B CB     1 
ATOM   2326 C  CG     . PRO B 1  27  ? 8.29484   16.14013  -21.71799 1.000 54.59871  ? 57  PRO B CG     1 
ATOM   2327 C  CD     . PRO B 1  27  ? 8.39267   16.90167  -23.00308 1.000 55.99731  ? 57  PRO B CD     1 
ATOM   2328 N  N      . PHE B 1  28  ? 5.10544   13.59278  -23.27040 1.000 53.49283  ? 58  PHE B N      1 
ATOM   2329 C  CA     . PHE B 1  28  ? 3.70961   13.43565  -22.87751 1.000 48.80364  ? 58  PHE B CA     1 
ATOM   2330 C  C      . PHE B 1  28  ? 3.56912   13.30596  -21.36733 1.000 44.96086  ? 58  PHE B C      1 
ATOM   2331 O  O      . PHE B 1  28  ? 2.63824   13.86658  -20.77677 1.000 46.22827  ? 58  PHE B O      1 
ATOM   2332 C  CB     . PHE B 1  28  ? 3.08786   12.21997  -23.55133 1.000 47.62801  ? 58  PHE B CB     1 
ATOM   2333 C  CG     . PHE B 1  28  ? 1.69839   11.91626  -23.06910 1.000 47.33052  ? 58  PHE B CG     1 
ATOM   2334 C  CD1    . PHE B 1  28  ? 0.60941   12.61172  -23.55894 1.000 44.04512  ? 58  PHE B CD1    1 
ATOM   2335 C  CD2    . PHE B 1  28  ? 1.48698   10.94621  -22.10648 1.000 45.28664  ? 58  PHE B CD2    1 
ATOM   2336 C  CE1    . PHE B 1  28  ? -0.66584  12.33379  -23.10685 1.000 44.21238  ? 58  PHE B CE1    1 
ATOM   2337 C  CE2    . PHE B 1  28  ? 0.21563   10.66540  -21.64989 1.000 41.49642  ? 58  PHE B CE2    1 
ATOM   2338 C  CZ     . PHE B 1  28  ? -0.86167  11.35067  -22.15005 1.000 40.43321  ? 58  PHE B CZ     1 
ATOM   2339 N  N      . LEU B 1  29  ? 4.45651   12.55176  -20.72871 1.000 49.23161  ? 59  LEU B N      1 
ATOM   2340 C  CA     . LEU B 1  29  ? 4.37687   12.37424  -19.28573 1.000 44.31446  ? 59  LEU B CA     1 
ATOM   2341 C  C      . LEU B 1  29  ? 5.76077   12.53263  -18.68372 1.000 42.21242  ? 59  LEU B C      1 
ATOM   2342 O  O      . LEU B 1  29  ? 6.71751   11.88258  -19.12383 1.000 43.57533  ? 59  LEU B O      1 
ATOM   2343 C  CB     . LEU B 1  29  ? 3.76485   11.01414  -18.92524 1.000 44.22512  ? 59  LEU B CB     1 
ATOM   2344 C  CG     . LEU B 1  29  ? 3.63300   10.69680  -17.43219 1.000 39.73718  ? 59  LEU B CG     1 
ATOM   2345 C  CD1    . LEU B 1  29  ? 2.70964   11.69071  -16.74822 1.000 38.11076  ? 59  LEU B CD1    1 
ATOM   2346 C  CD2    . LEU B 1  29  ? 3.09959   9.27930   -17.25473 1.000 41.95034  ? 59  LEU B CD2    1 
ATOM   2347 N  N      . VAL B 1  30  ? 5.86307   13.40818  -17.68840 1.000 43.38099  ? 60  VAL B N      1 
ATOM   2348 C  CA     . VAL B 1  30  ? 7.10227   13.60296  -16.94424 1.000 47.53134  ? 60  VAL B CA     1 
ATOM   2349 C  C      . VAL B 1  30  ? 6.88656   13.05848  -15.53928 1.000 44.62583  ? 60  VAL B C      1 
ATOM   2350 O  O      . VAL B 1  30  ? 5.93951   13.45922  -14.85271 1.000 42.81121  ? 60  VAL B O      1 
ATOM   2351 C  CB     . VAL B 1  30  ? 7.51614   15.08213  -16.89839 1.000 47.18816  ? 60  VAL B CB     1 
ATOM   2352 C  CG1    . VAL B 1  30  ? 8.68496   15.27296  -15.93086 1.000 43.71863  ? 60  VAL B CG1    1 
ATOM   2353 C  CG2    . VAL B 1  30  ? 7.84896   15.59714  -18.29021 1.000 44.34719  ? 60  VAL B CG2    1 
ATOM   2354 N  N      . LEU B 1  31  ? 7.74984   12.14370  -15.11590 1.000 46.63506  ? 61  LEU B N      1 
ATOM   2355 C  CA     . LEU B 1  31  ? 7.73056   11.60386  -13.76480 1.000 47.83051  ? 61  LEU B CA     1 
ATOM   2356 C  C      . LEU B 1  31  ? 8.81313   12.28605  -12.93499 1.000 47.51660  ? 61  LEU B C      1 
ATOM   2357 O  O      . LEU B 1  31  ? 9.98703   12.29335  -13.32147 1.000 45.26179  ? 61  LEU B O      1 
ATOM   2358 C  CB     . LEU B 1  31  ? 7.93975   10.08565  -13.78584 1.000 49.65170  ? 61  LEU B CB     1 
ATOM   2359 C  CG     . LEU B 1  31  ? 6.97537   9.27238   -14.65533 1.000 43.68500  ? 61  LEU B CG     1 
ATOM   2360 C  CD1    . LEU B 1  31  ? 7.37653   7.80303   -14.70906 1.000 44.65262  ? 61  LEU B CD1    1 
ATOM   2361 C  CD2    . LEU B 1  31  ? 5.54333   9.41884   -14.18040 1.000 44.19284  ? 61  LEU B CD2    1 
ATOM   2362 N  N      . LEU B 1  32  ? 8.41363   12.86483  -11.80409 1.000 42.38918  ? 62  LEU B N      1 
ATOM   2363 C  CA     . LEU B 1  32  ? 9.33232   13.47379  -10.84651 1.000 44.09655  ? 62  LEU B CA     1 
ATOM   2364 C  C      . LEU B 1  32  ? 9.26558   12.64441  -9.57016  1.000 39.62656  ? 62  LEU B C      1 
ATOM   2365 O  O      . LEU B 1  32  ? 8.23693   12.64163  -8.88340  1.000 45.96899  ? 62  LEU B O      1 
ATOM   2366 C  CB     . LEU B 1  32  ? 8.95911   14.93025  -10.59469 1.000 42.79386  ? 62  LEU B CB     1 
ATOM   2367 C  CG     . LEU B 1  32  ? 8.87051   15.79346  -11.86460 1.000 41.63897  ? 62  LEU B CG     1 
ATOM   2368 C  CD1    . LEU B 1  32  ? 8.35552   17.18294  -11.55834 1.000 42.20935  ? 62  LEU B CD1    1 
ATOM   2369 C  CD2    . LEU B 1  32  ? 10.21974  15.86339  -12.55609 1.000 52.66735  ? 62  LEU B CD2    1 
ATOM   2370 N  N      . VAL B 1  33  ? 10.35294  11.93938  -9.26381  1.000 37.62583  ? 63  VAL B N      1 
ATOM   2371 C  CA     . VAL B 1  33  ? 10.39143  10.94580  -8.19472  1.000 43.44446  ? 63  VAL B CA     1 
ATOM   2372 C  C      . VAL B 1  33  ? 11.22068  11.48621  -7.04118  1.000 48.50455  ? 63  VAL B C      1 
ATOM   2373 O  O      . VAL B 1  33  ? 12.39383  11.82710  -7.22073  1.000 50.34036  ? 63  VAL B O      1 
ATOM   2374 C  CB     . VAL B 1  33  ? 10.97035  9.61486   -8.69620  1.000 43.75721  ? 63  VAL B CB     1 
ATOM   2375 C  CG1    . VAL B 1  33  ? 11.02568  8.59892   -7.56992  1.000 40.79149  ? 63  VAL B CG1    1 
ATOM   2376 C  CG2    . VAL B 1  33  ? 10.13641  9.10225   -9.87191  1.000 42.26791  ? 63  VAL B CG2    1 
ATOM   2377 N  N      . THR B 1  34  ? 10.63204  11.51568  -5.85260  1.000 42.37494  ? 64  THR B N      1 
ATOM   2378 C  CA     . THR B 1  34  ? 11.35816  11.92294  -4.65800  1.000 46.08869  ? 64  THR B CA     1 
ATOM   2379 C  C      . THR B 1  34  ? 12.07435  10.72647  -4.03081  1.000 52.39262  ? 64  THR B C      1 
ATOM   2380 O  O      . THR B 1  34  ? 11.50944  9.63401   -3.93207  1.000 54.13754  ? 64  THR B O      1 
ATOM   2381 C  CB     . THR B 1  34  ? 10.39054  12.56786  -3.65938  1.000 49.60921  ? 64  THR B CB     1 
ATOM   2382 O  OG1    . THR B 1  34  ? 9.35989   11.63687  -3.31451  1.000 44.34837  ? 64  THR B OG1    1 
ATOM   2383 C  CG2    . THR B 1  34  ? 9.74128   13.80920  -4.25813  1.000 46.41161  ? 64  THR B CG2    1 
ATOM   2384 N  N      . SER B 1  35  ? 13.32883  10.93326  -3.62117  1.000 58.69684  ? 65  SER B N      1 
ATOM   2385 C  CA     . SER B 1  35  ? 14.08360  9.90686   -2.90484  1.000 57.24113  ? 65  SER B CA     1 
ATOM   2386 C  C      . SER B 1  35  ? 15.26787  10.55186  -2.19557  1.000 63.42248  ? 65  SER B C      1 
ATOM   2387 O  O      . SER B 1  35  ? 15.73163  11.63011  -2.57767  1.000 60.78692  ? 65  SER B O      1 
ATOM   2388 C  CB     . SER B 1  35  ? 14.58679  8.79434   -3.83303  1.000 54.45766  ? 65  SER B CB     1 
ATOM   2389 O  OG     . SER B 1  35  ? 15.56052  9.27268   -4.74354  1.000 52.88520  ? 65  SER B OG     1 
ATOM   2390 N  N      . SER B 1  36  ? 15.76145  9.86102   -1.16614  1.000 56.90074  ? 66  SER B N      1 
ATOM   2391 C  CA     . SER B 1  36  ? 16.92135  10.29741  -0.40377  1.000 58.09866  ? 66  SER B CA     1 
ATOM   2392 C  C      . SER B 1  36  ? 18.20766  9.84251   -1.08169  1.000 62.67792  ? 66  SER B C      1 
ATOM   2393 O  O      . SER B 1  36  ? 18.20779  9.01223   -1.99473  1.000 62.68188  ? 66  SER B O      1 
ATOM   2394 C  CB     . SER B 1  36  ? 16.88651  9.73817   1.01995   1.000 57.23702  ? 66  SER B CB     1 
ATOM   2395 O  OG     . SER B 1  36  ? 15.60536  9.85122   1.60713   1.000 66.99248  ? 66  SER B OG     1 
ATOM   2396 N  N      . HIS B 1  37  ? 19.32406  10.39813  -0.61144  1.000 61.43928  ? 67  HIS B N      1 
ATOM   2397 C  CA     . HIS B 1  37  ? 20.61427  10.05577  -1.19838  1.000 65.35470  ? 67  HIS B CA     1 
ATOM   2398 C  C      . HIS B 1  37  ? 20.91120  8.56888   -1.04685  1.000 64.49290  ? 67  HIS B C      1 
ATOM   2399 O  O      . HIS B 1  37  ? 21.36881  7.91691   -1.99307  1.000 61.55569  ? 67  HIS B O      1 
ATOM   2400 C  CB     . HIS B 1  37  ? 21.71312  10.89938  -0.55752  1.000 70.57027  ? 67  HIS B CB     1 
ATOM   2401 C  CG     . HIS B 1  37  ? 21.61179  12.35726  -0.88187  1.000 66.47946  ? 67  HIS B CG     1 
ATOM   2402 N  ND1    . HIS B 1  37  ? 22.51642  13.00269  -1.69644  1.000 67.84356  ? 67  HIS B ND1    1 
ATOM   2403 C  CD2    . HIS B 1  37  ? 20.70255  13.29120  -0.51501  1.000 67.90716  ? 67  HIS B CD2    1 
ATOM   2404 C  CE1    . HIS B 1  37  ? 22.17408  14.27347  -1.81149  1.000 69.06787  ? 67  HIS B CE1    1 
ATOM   2405 N  NE2    . HIS B 1  37  ? 21.07768  14.47520  -1.10286  1.000 65.12561  ? 67  HIS B NE2    1 
ATOM   2406 N  N      . LYS B 1  38  ? 20.64295  8.01288   0.13519   1.000 64.28883  ? 68  LYS B N      1 
ATOM   2407 C  CA     . LYS B 1  38  ? 20.97417  6.62132   0.41279   1.000 69.33976  ? 68  LYS B CA     1 
ATOM   2408 C  C      . LYS B 1  38  ? 20.08001  5.63847   -0.33485  1.000 69.91042  ? 68  LYS B C      1 
ATOM   2409 O  O      . LYS B 1  38  ? 20.42045  4.45293   -0.41610  1.000 65.89625  ? 68  LYS B O      1 
ATOM   2410 C  CB     . LYS B 1  38  ? 20.89174  6.36969   1.91662   1.000 75.21316  ? 68  LYS B CB     1 
ATOM   2411 C  CG     . LYS B 1  38  ? 19.50443  6.56997   2.49954   1.000 72.42231  ? 68  LYS B CG     1 
ATOM   2412 C  CD     . LYS B 1  38  ? 19.53324  6.40857   4.00782   1.000 79.76398  ? 68  LYS B CD     1 
ATOM   2413 C  CE     . LYS B 1  38  ? 18.24862  6.90748   4.64016   1.000 88.45766  ? 68  LYS B CE     1 
ATOM   2414 N  NZ     . LYS B 1  38  ? 18.23634  6.67251   6.10969   1.000 97.35528  ? 68  LYS B NZ     1 
ATOM   2415 N  N      . GLN B 1  39  ? 18.95447  6.09853   -0.88264  1.000 66.88799  ? 69  GLN B N      1 
ATOM   2416 C  CA     . GLN B 1  39  ? 17.99117  5.20897   -1.52350  1.000 63.06953  ? 69  GLN B CA     1 
ATOM   2417 C  C      . GLN B 1  39  ? 18.38984  4.86035   -2.95411  1.000 65.19180  ? 69  GLN B C      1 
ATOM   2418 O  O      . GLN B 1  39  ? 17.55367  4.88084   -3.86419  1.000 63.65287  ? 69  GLN B O      1 
ATOM   2419 C  CB     . GLN B 1  39  ? 16.59520  5.83395   -1.49265  1.000 59.03125  ? 69  GLN B CB     1 
ATOM   2420 C  CG     . GLN B 1  39  ? 16.05044  5.99377   -0.08510  1.000 59.81178  ? 69  GLN B CG     1 
ATOM   2421 C  CD     . GLN B 1  39  ? 14.60207  6.44286   -0.05540  1.000 57.85932  ? 69  GLN B CD     1 
ATOM   2422 O  OE1    . GLN B 1  39  ? 14.28238  7.57736   -0.39493  1.000 59.64771  ? 69  GLN B OE1    1 
ATOM   2423 N  NE2    . GLN B 1  39  ? 13.71636  5.54517   0.35058   1.000 58.97977  ? 69  GLN B NE2    1 
ATOM   2424 N  N      . LEU B 1  40  ? 19.66330  4.51533   -3.15563  1.000 63.25209  ? 70  LEU B N      1 
ATOM   2425 C  CA     . LEU B 1  40  ? 20.12076  4.11180   -4.48092  1.000 63.52510  ? 70  LEU B CA     1 
ATOM   2426 C  C      . LEU B 1  40  ? 19.35627  2.88779   -4.98342  1.000 63.23842  ? 70  LEU B C      1 
ATOM   2427 O  O      . LEU B 1  40  ? 19.05407  2.78130   -6.17893  1.000 58.89943  ? 70  LEU B O      1 
ATOM   2428 C  CB     . LEU B 1  40  ? 21.62346  3.82933   -4.44250  1.000 66.79702  ? 70  LEU B CB     1 
ATOM   2429 C  CG     . LEU B 1  40  ? 22.26694  3.35242   -5.74434  1.000 68.91587  ? 70  LEU B CG     1 
ATOM   2430 C  CD1    . LEU B 1  40  ? 22.06797  4.40003   -6.82927  1.000 67.28639  ? 70  LEU B CD1    1 
ATOM   2431 C  CD2    . LEU B 1  40  ? 23.74056  3.03825   -5.54942  1.000 66.95757  ? 70  LEU B CD2    1 
ATOM   2432 N  N      . ALA B 1  41  ? 19.04364  1.94621   -4.08792  1.000 59.28811  ? 71  ALA B N      1 
ATOM   2433 C  CA     . ALA B 1  41  ? 18.30058  0.75647   -4.49907  1.000 65.07315  ? 71  ALA B CA     1 
ATOM   2434 C  C      . ALA B 1  41  ? 16.93849  1.12237   -5.08103  1.000 62.21505  ? 71  ALA B C      1 
ATOM   2435 O  O      . ALA B 1  41  ? 16.52602  0.57061   -6.11036  1.000 60.64482  ? 71  ALA B O      1 
ATOM   2436 C  CB     . ALA B 1  41  ? 18.14268  -0.20231  -3.31746  1.000 61.86936  ? 71  ALA B CB     1 
ATOM   2437 N  N      . GLU B 1  42  ? 16.22693  2.04914   -4.43226  1.000 58.80015  ? 72  GLU B N      1 
ATOM   2438 C  CA     . GLU B 1  42  ? 14.94312  2.51940   -4.94702  1.000 63.10966  ? 72  GLU B CA     1 
ATOM   2439 C  C      . GLU B 1  42  ? 15.07666  3.06486   -6.36432  1.000 63.08923  ? 72  GLU B C      1 
ATOM   2440 O  O      . GLU B 1  42  ? 14.31959  2.68257   -7.26686  1.000 56.91526  ? 72  GLU B O      1 
ATOM   2441 C  CB     . GLU B 1  42  ? 14.37350  3.59964   -4.02476  1.000 58.40638  ? 72  GLU B CB     1 
ATOM   2442 C  CG     . GLU B 1  42  ? 13.66580  3.08632   -2.78511  1.000 61.83292  ? 72  GLU B CG     1 
ATOM   2443 C  CD     . GLU B 1  42  ? 14.62908  2.55501   -1.73396  1.000 64.95672  ? 72  GLU B CD     1 
ATOM   2444 O  OE1    . GLU B 1  42  ? 15.86073  2.63216   -1.94688  1.000 57.73117  ? 72  GLU B OE1    1 
ATOM   2445 O  OE2    . GLU B 1  42  ? 14.14818  2.07419   -0.68686  1.000 60.45165  ? 72  GLU B OE2    1 
ATOM   2446 N  N      . ARG B 1  43  ? 16.01428  3.99332   -6.56976  1.000 59.80916  ? 73  ARG B N      1 
ATOM   2447 C  CA     . ARG B 1  43  ? 16.13290  4.63060   -7.87545  1.000 56.08872  ? 73  ARG B CA     1 
ATOM   2448 C  C      . ARG B 1  43  ? 16.55076  3.62650   -8.93946  1.000 60.45937  ? 73  ARG B C      1 
ATOM   2449 O  O      . ARG B 1  43  ? 16.06596  3.67898   -10.07460 1.000 56.81853  ? 73  ARG B O      1 
ATOM   2450 C  CB     . ARG B 1  43  ? 17.11601  5.79935   -7.80480  1.000 58.20158  ? 73  ARG B CB     1 
ATOM   2451 C  CG     . ARG B 1  43  ? 16.63656  6.95258   -6.94397  1.000 58.30804  ? 73  ARG B CG     1 
ATOM   2452 C  CD     . ARG B 1  43  ? 17.54423  8.16057   -7.09568  1.000 59.79990  ? 73  ARG B CD     1 
ATOM   2453 N  NE     . ARG B 1  43  ? 18.85809  7.89256   -6.52108  1.000 59.85464  ? 73  ARG B NE     1 
ATOM   2454 C  CZ     . ARG B 1  43  ? 19.15178  8.01281   -5.23406  1.000 60.52031  ? 73  ARG B CZ     1 
ATOM   2455 N  NH1    . ARG B 1  43  ? 18.24504  8.39888   -4.35131  1.000 60.63639  ? 73  ARG B NH1    1 
ATOM   2456 N  NH2    . ARG B 1  43  ? 20.38030  7.71915   -4.81998  1.000 57.43854  ? 73  ARG B NH2    1 
ATOM   2457 N  N      . MET B 1  44  ? 17.44374  2.69997   -8.59485  1.000 59.10260  ? 74  MET B N      1 
ATOM   2458 C  CA     . MET B 1  44  ? 17.83863  1.68861   -9.56516  1.000 63.25466  ? 74  MET B CA     1 
ATOM   2459 C  C      . MET B 1  44  ? 16.65610  0.79829   -9.93383  1.000 59.86729  ? 74  MET B C      1 
ATOM   2460 O  O      . MET B 1  44  ? 16.45855  0.46662   -11.11081 1.000 56.40679  ? 74  MET B O      1 
ATOM   2461 C  CB     . MET B 1  44  ? 19.00110  0.86206   -9.01367  1.000 64.82147  ? 74  MET B CB     1 
ATOM   2462 C  CG     . MET B 1  44  ? 20.29345  1.65474   -8.85367  1.000 66.75780  ? 74  MET B CG     1 
ATOM   2463 S  SD     . MET B 1  44  ? 20.68935  2.65286   -10.31116 1.000 77.84529  ? 74  MET B SD     1 
ATOM   2464 C  CE     . MET B 1  44  ? 20.65737  1.41628   -11.60866 1.000 70.69213  ? 74  MET B CE     1 
ATOM   2465 N  N      . ALA B 1  45  ? 15.84938  0.41049   -8.94198  1.000 55.40574  ? 75  ALA B N      1 
ATOM   2466 C  CA     . ALA B 1  45  ? 14.67922  -0.40918  -9.22942  1.000 54.37794  ? 75  ALA B CA     1 
ATOM   2467 C  C      . ALA B 1  45  ? 13.70337  0.33629   -10.12487 1.000 55.15257  ? 75  ALA B C      1 
ATOM   2468 O  O      . ALA B 1  45  ? 13.08948  -0.25502  -11.02069 1.000 55.21121  ? 75  ALA B O      1 
ATOM   2469 C  CB     . ALA B 1  45  ? 13.99970  -0.83045  -7.92823  1.000 50.55783  ? 75  ALA B CB     1 
ATOM   2470 N  N      . ILE B 1  46  ? 13.54952  1.63940   -9.89924  1.000 54.40270  ? 76  ILE B N      1 
ATOM   2471 C  CA     . ILE B 1  46  ? 12.66182  2.42997   -10.74462 1.000 51.63006  ? 76  ILE B CA     1 
ATOM   2472 C  C      . ILE B 1  46  ? 13.21512  2.51012   -12.16210 1.000 51.88406  ? 76  ILE B C      1 
ATOM   2473 O  O      . ILE B 1  46  ? 12.48182  2.33390   -13.14356 1.000 51.48791  ? 76  ILE B O      1 
ATOM   2474 C  CB     . ILE B 1  46  ? 12.45112  3.82169   -10.12218 1.000 49.34186  ? 76  ILE B CB     1 
ATOM   2475 C  CG1    . ILE B 1  46  ? 11.66536  3.69191   -8.81889  1.000 41.11493  ? 76  ILE B CG1    1 
ATOM   2476 C  CG2    . ILE B 1  46  ? 11.72872  4.75095   -11.08430 1.000 44.84545  ? 76  ILE B CG2    1 
ATOM   2477 C  CD1    . ILE B 1  46  ? 11.69660  4.94662   -7.96058  1.000 44.54609  ? 76  ILE B CD1    1 
ATOM   2478 N  N      . ARG B 1  47  ? 14.51978  2.76114   -12.29191 1.000 52.60832  ? 77  ARG B N      1 
ATOM   2479 C  CA     . ARG B 1  47  ? 15.14292  2.83296   -13.61012 1.000 57.47575  ? 77  ARG B CA     1 
ATOM   2480 C  C      . ARG B 1  47  ? 14.99602  1.52594   -14.37209 1.000 57.25417  ? 77  ARG B C      1 
ATOM   2481 O  O      . ARG B 1  47  ? 14.94932  1.52793   -15.60649 1.000 58.35090  ? 77  ARG B O      1 
ATOM   2482 C  CB     . ARG B 1  47  ? 16.62224  3.18718   -13.47391 1.000 62.03136  ? 77  ARG B CB     1 
ATOM   2483 C  CG     . ARG B 1  47  ? 16.89023  4.62148   -13.06983 1.000 56.82403  ? 77  ARG B CG     1 
ATOM   2484 C  CD     . ARG B 1  47  ? 18.37748  4.91563   -13.11879 1.000 65.15622  ? 77  ARG B CD     1 
ATOM   2485 N  NE     . ARG B 1  47  ? 18.68896  6.24007   -12.59787 1.000 66.77828  ? 77  ARG B NE     1 
ATOM   2486 C  CZ     . ARG B 1  47  ? 19.28125  6.46130   -11.43187 1.000 69.11857  ? 77  ARG B CZ     1 
ATOM   2487 N  NH1    . ARG B 1  47  ? 19.67000  5.46329   -10.65256 1.000 69.08319  ? 77  ARG B NH1    1 
ATOM   2488 N  NH2    . ARG B 1  47  ? 19.49542  7.71423   -11.04009 1.000 69.09594  ? 77  ARG B NH2    1 
ATOM   2489 N  N      . GLN B 1  48  ? 14.94092  0.40215   -13.66148 1.000 59.20855  ? 78  GLN B N      1 
ATOM   2490 C  CA     . GLN B 1  48  ? 14.81393  -0.89498  -14.30947 1.000 57.90584  ? 78  GLN B CA     1 
ATOM   2491 C  C      . GLN B 1  48  ? 13.36511  -1.32408  -14.50057 1.000 52.52257  ? 78  GLN B C      1 
ATOM   2492 O  O      . GLN B 1  48  ? 13.12034  -2.36166  -15.12714 1.000 53.80711  ? 78  GLN B O      1 
ATOM   2493 C  CB     . GLN B 1  48  ? 15.56715  -1.95020  -13.49712 1.000 57.99443  ? 78  GLN B CB     1 
ATOM   2494 C  CG     . GLN B 1  48  ? 17.06644  -1.71638  -13.46503 1.000 66.96936  ? 78  GLN B CG     1 
ATOM   2495 C  CD     . GLN B 1  48  ? 17.71035  -2.24730  -12.20169 1.000 75.79322  ? 78  GLN B CD     1 
ATOM   2496 O  OE1    . GLN B 1  48  ? 17.08575  -2.97612  -11.42807 1.000 75.61576  ? 78  GLN B OE1    1 
ATOM   2497 N  NE2    . GLN B 1  48  ? 18.95923  -1.86176  -11.97089 1.000 78.77483  ? 78  GLN B NE2    1 
ATOM   2498 N  N      . THR B 1  49  ? 12.40664  -0.55905  -13.97687 1.000 53.44870  ? 79  THR B N      1 
ATOM   2499 C  CA     . THR B 1  49  ? 10.99612  -0.89331  -14.12192 1.000 52.88815  ? 79  THR B CA     1 
ATOM   2500 C  C      . THR B 1  49  ? 10.20009  0.26290   -14.72427 1.000 47.86107  ? 79  THR B C      1 
ATOM   2501 O  O      . THR B 1  49  ? 10.41604  0.61680   -15.88697 1.000 51.90413  ? 79  THR B O      1 
ATOM   2502 C  CB     . THR B 1  49  ? 10.41057  -1.31260  -12.77310 1.000 51.61210  ? 79  THR B CB     1 
ATOM   2503 O  OG1    . THR B 1  49  ? 10.62040  -0.27501  -11.80676 1.000 44.78431  ? 79  THR B OG1    1 
ATOM   2504 C  CG2    . THR B 1  49  ? 11.06579  -2.60944  -12.28969 1.000 50.13273  ? 79  THR B CG2    1 
ATOM   2505 N  N      . TRP B 1  50  ? 9.28896   0.87204   -13.95615 1.000 45.87680  ? 80  TRP B N      1 
ATOM   2506 C  CA     . TRP B 1  50  ? 8.39134   1.86012   -14.54995 1.000 46.01815  ? 80  TRP B CA     1 
ATOM   2507 C  C      . TRP B 1  50  ? 9.07061   3.18768   -14.86727 1.000 46.90806  ? 80  TRP B C      1 
ATOM   2508 O  O      . TRP B 1  50  ? 8.49693   3.99486   -15.60659 1.000 46.75038  ? 80  TRP B O      1 
ATOM   2509 C  CB     . TRP B 1  50  ? 7.17235   2.11305   -13.65619 1.000 43.79241  ? 80  TRP B CB     1 
ATOM   2510 C  CG     . TRP B 1  50  ? 7.45208   2.44888   -12.21177 1.000 41.51699  ? 80  TRP B CG     1 
ATOM   2511 C  CD1    . TRP B 1  50  ? 7.40563   1.58625   -11.15017 1.000 43.58830  ? 80  TRP B CD1    1 
ATOM   2512 C  CD2    . TRP B 1  50  ? 7.76152   3.73988   -11.66326 1.000 39.47094  ? 80  TRP B CD2    1 
ATOM   2513 N  NE1    . TRP B 1  50  ? 7.69337   2.25369   -9.98247  1.000 41.79136  ? 80  TRP B NE1    1 
ATOM   2514 C  CE2    . TRP B 1  50  ? 7.91277   3.57660   -10.26814 1.000 35.82476  ? 80  TRP B CE2    1 
ATOM   2515 C  CE3    . TRP B 1  50  ? 7.94069   5.01308   -12.21476 1.000 39.26556  ? 80  TRP B CE3    1 
ATOM   2516 C  CZ2    . TRP B 1  50  ? 8.23399   4.63625   -9.42130  1.000 39.07283  ? 80  TRP B CZ2    1 
ATOM   2517 C  CZ3    . TRP B 1  50  ? 8.26162   6.06881   -11.36889 1.000 40.32426  ? 80  TRP B CZ3    1 
ATOM   2518 C  CH2    . TRP B 1  50  ? 8.40154   5.87371   -9.98746  1.000 38.61718  ? 80  TRP B CH2    1 
ATOM   2519 N  N      . GLY B 1  51  ? 10.26243  3.44094   -14.34360 1.000 54.02601  ? 81  GLY B N      1 
ATOM   2520 C  CA     . GLY B 1  51  ? 10.92590  4.68405   -14.68833 1.000 51.75018  ? 81  GLY B CA     1 
ATOM   2521 C  C      . GLY B 1  51  ? 11.69206  4.65894   -15.99335 1.000 60.86480  ? 81  GLY B C      1 
ATOM   2522 O  O      . GLY B 1  51  ? 12.18621  5.70544   -16.42635 1.000 57.38229  ? 81  GLY B O      1 
ATOM   2523 N  N      . LYS B 1  52  ? 11.79191  3.49317   -16.63302 1.000 61.72738  ? 82  LYS B N      1 
ATOM   2524 C  CA     . LYS B 1  52  ? 12.54867  3.36860   -17.87301 1.000 67.06722  ? 82  LYS B CA     1 
ATOM   2525 C  C      . LYS B 1  52  ? 11.86959  4.18273   -18.97180 1.000 66.11089  ? 82  LYS B C      1 
ATOM   2526 O  O      . LYS B 1  52  ? 10.69593  3.95530   -19.29189 1.000 61.53609  ? 82  LYS B O      1 
ATOM   2527 C  CB     . LYS B 1  52  ? 12.66583  1.89795   -18.27238 1.000 65.08232  ? 82  LYS B CB     1 
ATOM   2528 C  CG     . LYS B 1  52  ? 13.51836  1.65909   -19.50995 1.000 67.02758  ? 82  LYS B CG     1 
ATOM   2529 C  CD     . LYS B 1  52  ? 13.84589  0.18222   -19.70460 1.000 67.60218  ? 82  LYS B CD     1 
ATOM   2530 C  CE     . LYS B 1  52  ? 14.56704  -0.41142  -18.50375 1.000 71.41060  ? 82  LYS B CE     1 
ATOM   2531 N  NZ     . LYS B 1  52  ? 16.04128  -0.21580  -18.59159 1.000 80.66094  ? 82  LYS B NZ     1 
ATOM   2532 N  N      . GLU B 1  53  ? 12.61219  5.12973   -19.54476 1.000 65.54602  ? 83  GLU B N      1 
ATOM   2533 C  CA     . GLU B 1  53  ? 12.05459  6.05202   -20.52633 1.000 63.47100  ? 83  GLU B CA     1 
ATOM   2534 C  C      . GLU B 1  53  ? 11.75378  5.33739   -21.83947 1.000 64.51279  ? 83  GLU B C      1 
ATOM   2535 O  O      . GLU B 1  53  ? 12.47925  4.42604   -22.25163 1.000 60.68426  ? 83  GLU B O      1 
ATOM   2536 C  CB     . GLU B 1  53  ? 13.01931  7.20978   -20.75120 1.000 64.25807  ? 83  GLU B CB     1 
ATOM   2537 C  CG     . GLU B 1  53  ? 13.25222  8.03485   -19.49875 1.000 64.14032  ? 83  GLU B CG     1 
ATOM   2538 C  CD     . GLU B 1  53  ? 13.98917  9.32175   -19.78546 1.000 65.67347  ? 83  GLU B CD     1 
ATOM   2539 O  OE1    . GLU B 1  53  ? 14.55649  9.43460   -20.89365 1.000 69.91337  ? 83  GLU B OE1    1 
ATOM   2540 O  OE2    . GLU B 1  53  ? 14.01403  10.21029  -18.90264 1.000 62.78804  ? 83  GLU B OE2    1 
ATOM   2541 N  N      . ARG B 1  54  ? 10.65562  5.73042   -22.48272 1.000 62.87208  ? 84  ARG B N      1 
ATOM   2542 C  CA     . ARG B 1  54  ? 10.20808  5.00517   -23.66451 1.000 64.02205  ? 84  ARG B CA     1 
ATOM   2543 C  C      . ARG B 1  54  ? 9.00517   5.70312   -24.28811 1.000 63.62178  ? 84  ARG B C      1 
ATOM   2544 O  O      . ARG B 1  54  ? 8.45372   6.66702   -23.74162 1.000 64.30575  ? 84  ARG B O      1 
ATOM   2545 C  CB     . ARG B 1  54  ? 9.87307   3.56343   -23.30324 1.000 65.68427  ? 84  ARG B CB     1 
ATOM   2546 C  CG     . ARG B 1  54  ? 8.95007   3.47716   -22.11557 1.000 65.37100  ? 84  ARG B CG     1 
ATOM   2547 C  CD     . ARG B 1  54  ? 8.48376   2.07184   -21.86088 1.000 69.26737  ? 84  ARG B CD     1 
ATOM   2548 N  NE     . ARG B 1  54  ? 7.70660   2.00741   -20.63056 1.000 69.41735  ? 84  ARG B NE     1 
ATOM   2549 C  CZ     . ARG B 1  54  ? 6.42206   1.69023   -20.57609 1.000 67.60858  ? 84  ARG B CZ     1 
ATOM   2550 N  NH1    . ARG B 1  54  ? 5.74559   1.36042   -21.66392 1.000 65.96742  ? 84  ARG B NH1    1 
ATOM   2551 N  NH2    . ARG B 1  54  ? 5.80424   1.69305   -19.39927 1.000 66.42237  ? 84  ARG B NH2    1 
ATOM   2552 N  N      . MET B 1  55  ? 8.61984   5.20160   -25.46110 1.000 62.06814  ? 85  MET B N      1 
ATOM   2553 C  CA     . MET B 1  55  ? 7.36997   5.57480   -26.10608 1.000 65.08214  ? 85  MET B CA     1 
ATOM   2554 C  C      . MET B 1  55  ? 6.24450   4.66949   -25.62854 1.000 66.35177  ? 85  MET B C      1 
ATOM   2555 O  O      . MET B 1  55  ? 6.37619   3.44169   -25.63249 1.000 72.93296  ? 85  MET B O      1 
ATOM   2556 C  CB     . MET B 1  55  ? 7.49750   5.51102   -27.62835 1.000 64.71041  ? 85  MET B CB     1 
ATOM   2557 C  CG     . MET B 1  55  ? 8.33254   6.63094   -28.21894 1.000 66.49491  ? 85  MET B CG     1 
ATOM   2558 S  SD     . MET B 1  55  ? 7.47297   8.21964   -28.10375 1.000 81.81799  ? 85  MET B SD     1 
ATOM   2559 C  CE     . MET B 1  55  ? 8.61958   9.29736   -28.95627 1.000 67.97038  ? 85  MET B CE     1 
ATOM   2560 N  N      . VAL B 1  56  ? 5.15195   5.29186   -25.19843 1.000 71.65756  ? 86  VAL B N      1 
ATOM   2561 C  CA     . VAL B 1  56  ? 3.95369   4.62675   -24.70825 1.000 73.38483  ? 86  VAL B CA     1 
ATOM   2562 C  C      . VAL B 1  56  ? 2.80814   5.07507   -25.60726 1.000 71.65955  ? 86  VAL B C      1 
ATOM   2563 O  O      . VAL B 1  56  ? 2.35610   6.22446   -25.51480 1.000 72.66025  ? 86  VAL B O      1 
ATOM   2564 C  CB     . VAL B 1  56  ? 3.67084   4.97878   -23.24010 1.000 66.49471  ? 86  VAL B CB     1 
ATOM   2565 C  CG1    . VAL B 1  56  ? 2.50311   4.16339   -22.70283 1.000 61.01031  ? 86  VAL B CG1    1 
ATOM   2566 C  CG2    . VAL B 1  56  ? 4.92275   4.78575   -22.38996 1.000 65.46859  ? 86  VAL B CG2    1 
ATOM   2567 N  N      . LYS B 1  57  ? 2.35189   4.18956   -26.49437 1.000 79.17468  ? 87  LYS B N      1 
ATOM   2568 C  CA     . LYS B 1  57  ? 1.29335   4.53265   -27.44721 1.000 77.50968  ? 87  LYS B CA     1 
ATOM   2569 C  C      . LYS B 1  57  ? 1.67610   5.76486   -28.26498 1.000 71.55714  ? 87  LYS B C      1 
ATOM   2570 O  O      . LYS B 1  57  ? 0.83429   6.61102   -28.57438 1.000 73.29221  ? 87  LYS B O      1 
ATOM   2571 C  CB     . LYS B 1  57  ? -0.03929  4.77288   -26.73240 1.000 76.81421  ? 87  LYS B CB     1 
ATOM   2572 C  CG     . LYS B 1  57  ? -0.58083  3.62635   -25.88325 1.000 77.77536  ? 87  LYS B CG     1 
ATOM   2573 C  CD     . LYS B 1  57  ? -1.17223  2.48317   -26.69121 1.000 75.19858  ? 87  LYS B CD     1 
ATOM   2574 C  CE     . LYS B 1  57  ? -1.74818  1.44321   -25.73640 1.000 80.62321  ? 87  LYS B CE     1 
ATOM   2575 N  NZ     . LYS B 1  57  ? -2.46754  0.32864   -26.40398 1.000 93.37743  ? 87  LYS B NZ     1 
ATOM   2576 N  N      . GLY B 1  58  ? 2.95520   5.86804   -28.62099 1.000 65.03761  ? 88  GLY B N      1 
ATOM   2577 C  CA     . GLY B 1  58  ? 3.44552   7.01470   -29.36059 1.000 67.77241  ? 88  GLY B CA     1 
ATOM   2578 C  C      . GLY B 1  58  ? 3.67425   8.27702   -28.55375 1.000 71.94876  ? 88  GLY B C      1 
ATOM   2579 O  O      . GLY B 1  58  ? 3.95870   9.32355   -29.14772 1.000 74.27119  ? 88  GLY B O      1 
ATOM   2580 N  N      . LYS B 1  59  ? 3.56989   8.21730   -27.22598 1.000 72.51846  ? 89  LYS B N      1 
ATOM   2581 C  CA     . LYS B 1  59  ? 3.76991   9.36484   -26.34445 1.000 67.71000  ? 89  LYS B CA     1 
ATOM   2582 C  C      . LYS B 1  59  ? 5.04722   9.19163   -25.52942 1.000 60.00802  ? 89  LYS B C      1 
ATOM   2583 O  O      . LYS B 1  59  ? 5.34187   8.09637   -25.05248 1.000 62.94531  ? 89  LYS B O      1 
ATOM   2584 C  CB     . LYS B 1  59  ? 2.57926   9.57096   -25.39835 1.000 62.31698  ? 89  LYS B CB     1 
ATOM   2585 C  CG     . LYS B 1  59  ? 1.27786   10.04406  -26.04675 1.000 63.66019  ? 89  LYS B CG     1 
ATOM   2586 C  CD     . LYS B 1  59  ? 0.64484   9.03551   -26.97796 1.000 71.44399  ? 89  LYS B CD     1 
ATOM   2587 C  CE     . LYS B 1  59  ? -0.58629  9.65029   -27.63681 1.000 70.21918  ? 89  LYS B CE     1 
ATOM   2588 N  NZ     . LYS B 1  59  ? -1.21891  8.74161   -28.63147 1.000 70.95396  ? 89  LYS B NZ     1 
ATOM   2589 N  N      . GLN B 1  60  ? 5.80320   10.27420  -25.36664 1.000 55.41424  ? 90  GLN B N      1 
ATOM   2590 C  CA     . GLN B 1  60  ? 7.10536   10.20198  -24.70896 1.000 61.00228  ? 90  GLN B CA     1 
ATOM   2591 C  C      . GLN B 1  60  ? 6.98920   10.21436  -23.18402 1.000 56.78646  ? 90  GLN B C      1 
ATOM   2592 O  O      . GLN B 1  60  ? 6.27808   11.05287  -22.60866 1.000 52.73027  ? 90  GLN B O      1 
ATOM   2593 C  CB     . GLN B 1  60  ? 7.98970   11.35892  -25.16932 1.000 60.37708  ? 90  GLN B CB     1 
ATOM   2594 C  CG     . GLN B 1  60  ? 9.34446   11.37560  -24.49141 1.000 58.03002  ? 90  GLN B CG     1 
ATOM   2595 C  CD     . GLN B 1  60  ? 10.21174  10.21779  -24.92893 1.000 60.39381  ? 90  GLN B CD     1 
ATOM   2596 O  OE1    . GLN B 1  60  ? 10.47560  10.04149  -26.11594 1.000 70.27219  ? 90  GLN B OE1    1 
ATOM   2597 N  NE2    . GLN B 1  60  ? 10.63423  9.40116   -23.97317 1.000 61.61588  ? 90  GLN B NE2    1 
ATOM   2598 N  N      . LEU B 1  61  ? 7.70760   9.29140   -22.53236 1.000 58.09965  ? 91  LEU B N      1 
ATOM   2599 C  CA     . LEU B 1  61  ? 7.81640   9.23694   -21.07760 1.000 48.59942  ? 91  LEU B CA     1 
ATOM   2600 C  C      . LEU B 1  61  ? 9.21670   9.65477   -20.64999 1.000 54.49009  ? 91  LEU B C      1 
ATOM   2601 O  O      . LEU B 1  61  ? 10.21017  9.14219   -21.17728 1.000 56.78454  ? 91  LEU B O      1 
ATOM   2602 C  CB     . LEU B 1  61  ? 7.52432   7.83098   -20.54980 1.000 54.84625  ? 91  LEU B CB     1 
ATOM   2603 C  CG     . LEU B 1  61  ? 7.90513   7.63844   -19.07641 1.000 53.66004  ? 91  LEU B CG     1 
ATOM   2604 C  CD1    . LEU B 1  61  ? 6.82847   8.24180   -18.17768 1.000 48.74099  ? 91  LEU B CD1    1 
ATOM   2605 C  CD2    . LEU B 1  61  ? 8.16246   6.17542   -18.72651 1.000 57.78578  ? 91  LEU B CD2    1 
ATOM   2606 N  N      . LYS B 1  62  ? 9.29593   10.56867  -19.68247 1.000 53.22449  ? 92  LYS B N      1 
ATOM   2607 C  CA     . LYS B 1  62  ? 10.57127  10.98596  -19.11532 1.000 56.66635  ? 92  LYS B CA     1 
ATOM   2608 C  C      . LYS B 1  62  ? 10.53300  10.80105  -17.60702 1.000 54.08245  ? 92  LYS B C      1 
ATOM   2609 O  O      . LYS B 1  62  ? 9.48950   10.97676  -16.98346 1.000 51.96559  ? 92  LYS B O      1 
ATOM   2610 C  CB     . LYS B 1  62  ? 10.88085  12.44472  -19.46007 1.000 54.30352  ? 92  LYS B CB     1 
ATOM   2611 C  CG     . LYS B 1  62  ? 10.89333  12.72858  -20.95549 1.000 57.85161  ? 92  LYS B CG     1 
ATOM   2612 C  CD     . LYS B 1  62  ? 12.14893  12.17272  -21.63251 1.000 55.62385  ? 92  LYS B CD     1 
ATOM   2613 C  CE     . LYS B 1  62  ? 13.41969  12.81421  -21.08988 1.000 58.64174  ? 92  LYS B CE     1 
ATOM   2614 N  NZ     . LYS B 1  62  ? 14.64392  12.12746  -21.59537 1.000 60.74333  ? 92  LYS B NZ     1 
ATOM   2615 N  N      . THR B 1  63  ? 11.67308  10.44020  -17.02236 1.000 53.32321  ? 93  THR B N      1 
ATOM   2616 C  CA     . THR B 1  63  ? 11.73003  10.15499  -15.59421 1.000 53.82219  ? 93  THR B CA     1 
ATOM   2617 C  C      . THR B 1  63  ? 12.94992  10.81220  -14.97298 1.000 56.48161  ? 93  THR B C      1 
ATOM   2618 O  O      . THR B 1  63  ? 14.07757  10.57951  -15.42045 1.000 61.02963  ? 93  THR B O      1 
ATOM   2619 C  CB     . THR B 1  63  ? 11.77281  8.64539   -15.32265 1.000 57.77229  ? 93  THR B CB     1 
ATOM   2620 O  OG1    . THR B 1  63  ? 10.59286  8.02226   -15.84861 1.000 55.28534  ? 93  THR B OG1    1 
ATOM   2621 C  CG2    . THR B 1  63  ? 11.86706  8.38303   -13.82110 1.000 56.06437  ? 93  THR B CG2    1 
ATOM   2622 N  N      . PHE B 1  64  ? 12.72104  11.60495  -13.92395 1.000 55.24769  ? 94  PHE B N      1 
ATOM   2623 C  CA     . PHE B 1  64  ? 13.77744  12.31237  -13.21780 1.000 61.02340  ? 94  PHE B CA     1 
ATOM   2624 C  C      . PHE B 1  64  ? 13.61213  12.10591  -11.72082 1.000 52.93803  ? 94  PHE B C      1 
ATOM   2625 O  O      . PHE B 1  64  ? 12.50426  11.88122  -11.22453 1.000 49.47302  ? 94  PHE B O      1 
ATOM   2626 C  CB     . PHE B 1  64  ? 13.76780  13.81348  -13.54664 1.000 59.15188  ? 94  PHE B CB     1 
ATOM   2627 C  CG     . PHE B 1  64  ? 13.71481  14.10362  -15.01929 1.000 63.29926  ? 94  PHE B CG     1 
ATOM   2628 C  CD1    . PHE B 1  64  ? 14.81902  13.87265  -15.82307 1.000 64.44066  ? 94  PHE B CD1    1 
ATOM   2629 C  CD2    . PHE B 1  64  ? 12.55774  14.59153  -15.60399 1.000 63.84264  ? 94  PHE B CD2    1 
ATOM   2630 C  CE1    . PHE B 1  64  ? 14.77211  14.13010  -17.18150 1.000 61.19947  ? 94  PHE B CE1    1 
ATOM   2631 C  CE2    . PHE B 1  64  ? 12.50727  14.84872  -16.96203 1.000 60.94403  ? 94  PHE B CE2    1 
ATOM   2632 C  CZ     . PHE B 1  64  ? 13.61553  14.61589  -17.75086 1.000 61.10466  ? 94  PHE B CZ     1 
ATOM   2633 N  N      . PHE B 1  65  ? 14.73026  12.17555  -11.01057 1.000 57.75437  ? 95  PHE B N      1 
ATOM   2634 C  CA     . PHE B 1  65  ? 14.76218  12.00953  -9.56741  1.000 55.49470  ? 95  PHE B CA     1 
ATOM   2635 C  C      . PHE B 1  65  ? 15.13774  13.32950  -8.91268  1.000 56.45828  ? 95  PHE B C      1 
ATOM   2636 O  O      . PHE B 1  65  ? 16.17347  13.91532  -9.23758  1.000 60.07531  ? 95  PHE B O      1 
ATOM   2637 C  CB     . PHE B 1  65  ? 15.75664  10.92011  -9.17434  1.000 55.19208  ? 95  PHE B CB     1 
ATOM   2638 C  CG     . PHE B 1  65  ? 15.41882  9.57048   -9.73298  1.000 57.59341  ? 95  PHE B CG     1 
ATOM   2639 C  CD1    . PHE B 1  65  ? 15.91188  9.17376   -10.96615 1.000 60.56043  ? 95  PHE B CD1    1 
ATOM   2640 C  CD2    . PHE B 1  65  ? 14.60948  8.69793   -9.02727  1.000 56.50155  ? 95  PHE B CD2    1 
ATOM   2641 C  CE1    . PHE B 1  65  ? 15.60563  7.93194   -11.48248 1.000 60.95634  ? 95  PHE B CE1    1 
ATOM   2642 C  CE2    . PHE B 1  65  ? 14.29747  7.45514   -9.53883  1.000 53.32001  ? 95  PHE B CE2    1 
ATOM   2643 C  CZ     . PHE B 1  65  ? 14.79741  7.07141   -10.76669 1.000 57.60470  ? 95  PHE B CZ     1 
ATOM   2644 N  N      . LEU B 1  66  ? 14.31197  13.77025  -7.97184  1.000 56.96068  ? 96  LEU B N      1 
ATOM   2645 C  CA     . LEU B 1  66  ? 14.50220  15.03347  -7.27749  1.000 57.30066  ? 96  LEU B CA     1 
ATOM   2646 C  C      . LEU B 1  66  ? 15.35372  14.79633  -6.03730  1.000 59.34229  ? 96  LEU B C      1 
ATOM   2647 O  O      . LEU B 1  66  ? 15.02353  13.94685  -5.20015  1.000 56.22472  ? 96  LEU B O      1 
ATOM   2648 C  CB     . LEU B 1  66  ? 13.15158  15.63741  -6.88957  1.000 48.48483  ? 96  LEU B CB     1 
ATOM   2649 C  CG     . LEU B 1  66  ? 12.12707  15.76149  -8.01649  1.000 48.00414  ? 96  LEU B CG     1 
ATOM   2650 C  CD1    . LEU B 1  66  ? 10.82167  16.32350  -7.48734  1.000 45.61818  ? 96  LEU B CD1    1 
ATOM   2651 C  CD2    . LEU B 1  66  ? 12.67296  16.64157  -9.12704  1.000 58.06688  ? 96  LEU B CD2    1 
ATOM   2652 N  N      . LEU B 1  67  ? 16.45556  15.53544  -5.93186  1.000 65.05023  ? 97  LEU B N      1 
ATOM   2653 C  CA     . LEU B 1  67  ? 17.37043  15.42672  -4.80863  1.000 64.34095  ? 97  LEU B CA     1 
ATOM   2654 C  C      . LEU B 1  67  ? 17.73214  16.81702  -4.31089  1.000 65.47912  ? 97  LEU B C      1 
ATOM   2655 O  O      . LEU B 1  67  ? 17.74815  17.78567  -5.07366  1.000 61.54626  ? 97  LEU B O      1 
ATOM   2656 C  CB     . LEU B 1  67  ? 18.65607  14.66449  -5.18304  1.000 58.54907  ? 97  LEU B CB     1 
ATOM   2657 C  CG     . LEU B 1  67  ? 18.59866  13.13264  -5.18911  1.000 65.30880  ? 97  LEU B CG     1 
ATOM   2658 C  CD1    . LEU B 1  67  ? 19.83097  12.53432  -5.86206  1.000 67.48379  ? 97  LEU B CD1    1 
ATOM   2659 C  CD2    . LEU B 1  67  ? 18.44233  12.58395  -3.77556  1.000 65.88965  ? 97  LEU B CD2    1 
ATOM   2660 N  N      . GLY B 1  68  ? 17.99602  16.90617  -3.01725  1.000 68.38267  ? 98  GLY B N      1 
ATOM   2661 C  CA     . GLY B 1  68  ? 18.61502  18.06175  -2.41293  1.000 70.69417  ? 98  GLY B CA     1 
ATOM   2662 C  C      . GLY B 1  68  ? 20.08949  17.82673  -2.16981  1.000 67.44354  ? 98  GLY B C      1 
ATOM   2663 O  O      . GLY B 1  68  ? 20.76829  17.13181  -2.93558  1.000 69.68069  ? 98  GLY B O      1 
ATOM   2664 N  N      . THR B 1  69  ? 20.59414  18.39858  -1.08406  1.000 74.41513  ? 99  THR B N      1 
ATOM   2665 C  CA     . THR B 1  69  ? 21.99014  18.24771  -0.71655  1.000 74.08588  ? 99  THR B CA     1 
ATOM   2666 C  C      . THR B 1  69  ? 22.08615  17.51035  0.61237   1.000 73.06630  ? 99  THR B C      1 
ATOM   2667 O  O      . THR B 1  69  ? 21.10359  17.39290  1.35108   1.000 68.49410  ? 99  THR B O      1 
ATOM   2668 C  CB     . THR B 1  69  ? 22.67501  19.60913  -0.61589  1.000 67.20777  ? 99  THR B CB     1 
ATOM   2669 O  OG1    . THR B 1  69  ? 21.93635  20.43540  0.28814   1.000 71.84437  ? 99  THR B OG1    1 
ATOM   2670 C  CG2    . THR B 1  69  ? 22.68703  20.27746  -1.97298  1.000 75.17775  ? 99  THR B CG2    1 
ATOM   2671 N  N      . THR B 1  70  ? 23.28646  17.02032  0.92101   1.000 69.65004  ? 100 THR B N      1 
ATOM   2672 C  CA     . THR B 1  70  ? 23.49758  16.26768  2.14695   1.000 72.24144  ? 100 THR B CA     1 
ATOM   2673 C  C      . THR B 1  70  ? 24.82933  16.65804  2.76776   1.000 79.86341  ? 100 THR B C      1 
ATOM   2674 O  O      . THR B 1  70  ? 25.76050  17.07847  2.07654   1.000 80.01496  ? 100 THR B O      1 
ATOM   2675 C  CB     . THR B 1  70  ? 23.46659  14.74895  1.89600   1.000 76.76867  ? 100 THR B CB     1 
ATOM   2676 O  OG1    . THR B 1  70  ? 23.76250  14.05055  3.11163   1.000 81.39366  ? 100 THR B OG1    1 
ATOM   2677 C  CG2    . THR B 1  70  ? 24.48832  14.35440  0.83537   1.000 76.95213  ? 100 THR B CG2    1 
ATOM   2678 N  N      . SER B 1  71  ? 24.90464  16.50492  4.09029   1.000 87.78116  ? 101 SER B N      1 
ATOM   2679 C  CA     . SER B 1  71  ? 26.15189  16.74076  4.80746   1.000 85.95844  ? 101 SER B CA     1 
ATOM   2680 C  C      . SER B 1  71  ? 27.15386  15.60817  4.59232   1.000 88.21379  ? 101 SER B C      1 
ATOM   2681 O  O      . SER B 1  71  ? 28.36768  15.84683  4.58611   1.000 93.17963  ? 101 SER B O      1 
ATOM   2682 C  CB     . SER B 1  71  ? 25.85302  16.93050  6.29402   1.000 72.91396  ? 101 SER B CB     1 
ATOM   2683 O  OG     . SER B 1  71  ? 25.50151  15.69542  6.88936   1.000 80.69942  ? 101 SER B OG     1 
ATOM   2684 N  N      . SER B 1  72  ? 26.67085  14.38027  4.41468   1.000 79.75072  ? 102 SER B N      1 
ATOM   2685 C  CA     . SER B 1  72  ? 27.55165  13.22946  4.25146   1.000 85.58934  ? 102 SER B CA     1 
ATOM   2686 C  C      . SER B 1  72  ? 28.40803  13.36936  3.00105   1.000 81.47933  ? 102 SER B C      1 
ATOM   2687 O  O      . SER B 1  72  ? 27.88581  13.48971  1.88810   1.000 78.45725  ? 102 SER B O      1 
ATOM   2688 C  CB     . SER B 1  72  ? 26.72855  11.94406  4.18443   1.000 86.23780  ? 102 SER B CB     1 
ATOM   2689 O  OG     . SER B 1  72  ? 27.51713  10.86421  3.71425   1.000 82.96090  ? 102 SER B OG     1 
ATOM   2690 N  N      . ALA B 1  73  ? 29.72990  13.33693  3.18636   1.000 86.47502  ? 103 ALA B N      1 
ATOM   2691 C  CA     . ALA B 1  73  ? 30.62938  13.38675  2.03910   1.000 82.56888  ? 103 ALA B CA     1 
ATOM   2692 C  C      . ALA B 1  73  ? 30.48927  12.13500  1.18476   1.000 85.26342  ? 103 ALA B C      1 
ATOM   2693 O  O      . ALA B 1  73  ? 30.55328  12.20514  -0.04997  1.000 83.84932  ? 103 ALA B O      1 
ATOM   2694 C  CB     . ALA B 1  73  ? 32.07514  13.54884  2.51332   1.000 69.74286  ? 103 ALA B CB     1 
ATOM   2695 N  N      . ALA B 1  74  ? 30.26681  10.98444  1.82677   1.000 88.19815  ? 104 ALA B N      1 
ATOM   2696 C  CA     . ALA B 1  74  ? 30.07467  9.73726   1.09105   1.000 86.61336  ? 104 ALA B CA     1 
ATOM   2697 C  C      . ALA B 1  74  ? 28.82946  9.80323   0.21344   1.000 88.68209  ? 104 ALA B C      1 
ATOM   2698 O  O      . ALA B 1  74  ? 28.86698  9.43943   -0.96823  1.000 87.53537  ? 104 ALA B O      1 
ATOM   2699 C  CB     . ALA B 1  74  ? 29.99088  8.56203   2.06478   1.000 75.92638  ? 104 ALA B CB     1 
ATOM   2700 N  N      . GLU B 1  75  ? 27.70627  10.24836  0.78394   1.000 87.42262  ? 105 GLU B N      1 
ATOM   2701 C  CA     . GLU B 1  75  ? 26.47794  10.36587  0.00330   1.000 87.32367  ? 105 GLU B CA     1 
ATOM   2702 C  C      . GLU B 1  75  ? 26.60823  11.41446  -1.09623  1.000 87.78365  ? 105 GLU B C      1 
ATOM   2703 O  O      . GLU B 1  75  ? 26.11248  11.21448  -2.21167  1.000 89.33243  ? 105 GLU B O      1 
ATOM   2704 C  CB     . GLU B 1  75  ? 25.29727  10.68671  0.91908   1.000 83.50432  ? 105 GLU B CB     1 
ATOM   2705 C  CG     . GLU B 1  75  ? 24.87924  9.53575   1.81744   1.000 76.46107  ? 105 GLU B CG     1 
ATOM   2706 C  CD     . GLU B 1  75  ? 23.74098  9.91143   2.74351   1.000 77.27985  ? 105 GLU B CD     1 
ATOM   2707 O  OE1    . GLU B 1  75  ? 23.33372  11.09096  2.73131   1.000 78.37204  ? 105 GLU B OE1    1 
ATOM   2708 O  OE2    . GLU B 1  75  ? 23.24361  9.02716   3.47178   1.000 79.80167  ? 105 GLU B OE2    1 
ATOM   2709 N  N      . THR B 1  76  ? 27.25147  12.54782  -0.80187  1.000 81.85666  ? 106 THR B N      1 
ATOM   2710 C  CA     . THR B 1  76  ? 27.48511  13.53322  -1.85224  1.000 84.61408  ? 106 THR B CA     1 
ATOM   2711 C  C      . THR B 1  76  ? 28.26455  12.91667  -3.00539  1.000 91.90417  ? 106 THR B C      1 
ATOM   2712 O  O      . THR B 1  76  ? 27.91403  13.10697  -4.17645  1.000 90.62200  ? 106 THR B O      1 
ATOM   2713 C  CB     . THR B 1  76  ? 28.21815  14.75309  -1.29748  1.000 83.61956  ? 106 THR B CB     1 
ATOM   2714 O  OG1    . THR B 1  76  ? 27.46618  15.31208  -0.21438  1.000 75.45978  ? 106 THR B OG1    1 
ATOM   2715 C  CG2    . THR B 1  76  ? 28.37752  15.80304  -2.38539  1.000 86.54727  ? 106 THR B CG2    1 
ATOM   2716 N  N      . LYS B 1  77  ? 29.31510  12.15635  -2.69113  1.000 87.17044  ? 107 LYS B N      1 
ATOM   2717 C  CA     . LYS B 1  77  ? 30.11547  11.52525  -3.73592  1.000 93.37616  ? 107 LYS B CA     1 
ATOM   2718 C  C      . LYS B 1  77  ? 29.28935  10.51700  -4.53002  1.000 94.19882  ? 107 LYS B C      1 
ATOM   2719 O  O      . LYS B 1  77  ? 29.33219  10.48801  -5.77220  1.000 95.05836  ? 107 LYS B O      1 
ATOM   2720 C  CB     . LYS B 1  77  ? 31.33274  10.84985  -3.09648  1.000 89.26463  ? 107 LYS B CB     1 
ATOM   2721 C  CG     . LYS B 1  77  ? 32.22741  10.08570  -4.05747  1.000 89.02090  ? 107 LYS B CG     1 
ATOM   2722 C  CD     . LYS B 1  77  ? 32.67273  10.96660  -5.20915  1.000 89.27664  ? 107 LYS B CD     1 
ATOM   2723 C  CE     . LYS B 1  77  ? 33.18262  12.30871  -4.71125  1.000 79.66383  ? 107 LYS B CE     1 
ATOM   2724 N  NZ     . LYS B 1  77  ? 33.52843  13.20321  -5.84317  1.000 72.78372  ? 107 LYS B NZ     1 
ATOM   2725 N  N      . GLU B 1  78  ? 28.52868  9.67976   -3.82054  1.000 91.53910  ? 108 GLU B N      1 
ATOM   2726 C  CA     . GLU B 1  78  ? 27.67560  8.69351   -4.47487  1.000 92.70404  ? 108 GLU B CA     1 
ATOM   2727 C  C      . GLU B 1  78  ? 26.71141  9.35816   -5.44768  1.000 90.65555  ? 108 GLU B C      1 
ATOM   2728 O  O      . GLU B 1  78  ? 26.56811  8.91768   -6.59298  1.000 87.60816  ? 108 GLU B O      1 
ATOM   2729 C  CB     . GLU B 1  78  ? 26.92019  7.87847   -3.42271  1.000 90.96807  ? 108 GLU B CB     1 
ATOM   2730 C  CG     . GLU B 1  78  ? 27.81870  6.96235   -2.59875  1.000 95.33308  ? 108 GLU B CG     1 
ATOM   2731 C  CD     . GLU B 1  78  ? 27.18394  6.51590   -1.29252  1.000 96.95501  ? 108 GLU B CD     1 
ATOM   2732 O  OE1    . GLU B 1  78  ? 25.96559  6.72983   -1.10841  1.000 96.77781  ? 108 GLU B OE1    1 
ATOM   2733 O  OE2    . GLU B 1  78  ? 27.91014  5.95053   -0.44651  1.000 94.12228  ? 108 GLU B OE2    1 
ATOM   2734 N  N      . VAL B 1  79  ? 26.03862  10.42375  -5.00614  1.000 92.69631  ? 109 VAL B N      1 
ATOM   2735 C  CA     . VAL B 1  79  ? 25.05403  11.08271  -5.85852  1.000 93.12545  ? 109 VAL B CA     1 
ATOM   2736 C  C      . VAL B 1  79  ? 25.73050  11.78689  -7.02754  1.000 91.85453  ? 109 VAL B C      1 
ATOM   2737 O  O      . VAL B 1  79  ? 25.17435  11.84022  -8.12940  1.000 87.95032  ? 109 VAL B O      1 
ATOM   2738 C  CB     . VAL B 1  79  ? 24.19039  12.05895  -5.03788  1.000 87.78690  ? 109 VAL B CB     1 
ATOM   2739 C  CG1    . VAL B 1  79  ? 23.54906  13.09690  -5.95144  1.000 80.16310  ? 109 VAL B CG1    1 
ATOM   2740 C  CG2    . VAL B 1  79  ? 23.12067  11.29865  -4.26421  1.000 78.33204  ? 109 VAL B CG2    1 
ATOM   2741 N  N      . ASP B 1  80  ? 26.92833  12.33951  -6.81959  1.000 91.42536  ? 110 ASP B N      1 
ATOM   2742 C  CA     . ASP B 1  80  ? 27.65354  12.95722  -7.92595  1.000 93.82252  ? 110 ASP B CA     1 
ATOM   2743 C  C      . ASP B 1  80  ? 27.93293  11.94296  -9.03093  1.000 91.01992  ? 110 ASP B C      1 
ATOM   2744 O  O      . ASP B 1  80  ? 27.61970  12.17577  -10.21005 1.000 83.69014  ? 110 ASP B O      1 
ATOM   2745 C  CB     . ASP B 1  80  ? 28.96069  13.55526  -7.40529  1.000 95.72914  ? 110 ASP B CB     1 
ATOM   2746 C  CG     . ASP B 1  80  ? 28.73600  14.60654  -6.33628  1.000 97.89047  ? 110 ASP B CG     1 
ATOM   2747 O  OD1    . ASP B 1  80  ? 27.61981  15.16588  -6.27218  1.000 96.15688  ? 110 ASP B OD1    1 
ATOM   2748 O  OD2    . ASP B 1  80  ? 29.66901  14.85066  -5.53982  1.000 93.31520  ? 110 ASP B OD2    1 
ATOM   2749 N  N      . GLN B 1  81  ? 28.51522  10.79668  -8.66111  1.000 92.97775  ? 111 GLN B N      1 
ATOM   2750 C  CA     . GLN B 1  81  ? 28.80908  9.77620   -9.66672  1.000 95.77279  ? 111 GLN B CA     1 
ATOM   2751 C  C      . GLN B 1  81  ? 27.53172  9.20345   -10.27273 1.000 91.84890  ? 111 GLN B C      1 
ATOM   2752 O  O      . GLN B 1  81  ? 27.48806  8.89994   -11.47120 1.000 87.71283  ? 111 GLN B O      1 
ATOM   2753 C  CB     . GLN B 1  81  ? 29.68904  8.67037   -9.08206  1.000 95.46432  ? 111 GLN B CB     1 
ATOM   2754 C  CG     . GLN B 1  81  ? 31.08802  9.14870   -8.70142  1.000 94.25824  ? 111 GLN B CG     1 
ATOM   2755 C  CD     . GLN B 1  81  ? 31.91366  8.08501   -7.99675  1.000 91.01776  ? 111 GLN B CD     1 
ATOM   2756 O  OE1    . GLN B 1  81  ? 31.43874  7.41211   -7.08057  1.000 95.61782  ? 111 GLN B OE1    1 
ATOM   2757 N  NE2    . GLN B 1  81  ? 33.15992  7.92436   -8.43166  1.000 79.17987  ? 111 GLN B NE2    1 
ATOM   2758 N  N      . GLU B 1  82  ? 26.48817  9.03048   -9.46196  1.000 88.75255  ? 112 GLU B N      1 
ATOM   2759 C  CA     . GLU B 1  82  ? 25.22182  8.53884   -9.98791  1.000 88.12611  ? 112 GLU B CA     1 
ATOM   2760 C  C      . GLU B 1  82  ? 24.64827  9.50370   -11.01806 1.000 84.65243  ? 112 GLU B C      1 
ATOM   2761 O  O      . GLU B 1  82  ? 24.14650  9.07908   -12.06699 1.000 82.13858  ? 112 GLU B O      1 
ATOM   2762 C  CB     . GLU B 1  82  ? 24.24374  8.31382   -8.83514  1.000 87.04623  ? 112 GLU B CB     1 
ATOM   2763 C  CG     . GLU B 1  82  ? 22.88377  7.77795   -9.24045  1.000 84.45330  ? 112 GLU B CG     1 
ATOM   2764 C  CD     . GLU B 1  82  ? 21.96075  7.61663   -8.04928  1.000 77.53257  ? 112 GLU B CD     1 
ATOM   2765 O  OE1    . GLU B 1  82  ? 22.43726  7.77265   -6.90523  1.000 81.79881  ? 112 GLU B OE1    1 
ATOM   2766 O  OE2    . GLU B 1  82  ? 20.76271  7.33493   -8.25224  1.000 77.31499  ? 112 GLU B OE2    1 
ATOM   2767 N  N      . SER B 1  83  ? 24.71604  10.80911  -10.73783 1.000 82.58099  ? 113 SER B N      1 
ATOM   2768 C  CA     . SER B 1  83  ? 24.24451  11.79793  -11.69894 1.000 82.42328  ? 113 SER B CA     1 
ATOM   2769 C  C      . SER B 1  83  ? 25.05777  11.74374  -12.98387 1.000 87.74964  ? 113 SER B C      1 
ATOM   2770 O  O      . SER B 1  83  ? 24.49828  11.84454  -14.08319 1.000 80.79653  ? 113 SER B O      1 
ATOM   2771 C  CB     . SER B 1  83  ? 24.29959  13.19847  -11.08710 1.000 82.53293  ? 113 SER B CB     1 
ATOM   2772 O  OG     . SER B 1  83  ? 23.86350  14.17806  -12.01752 1.000 74.61464  ? 113 SER B OG     1 
ATOM   2773 N  N      . GLN B 1  84  ? 26.38077  11.57453  -12.87315 1.000 88.27633  ? 114 GLN B N      1 
ATOM   2774 C  CA     . GLN B 1  84  ? 27.17705  11.47463  -14.09575 1.000 87.32910  ? 114 GLN B CA     1 
ATOM   2775 C  C      . GLN B 1  84  ? 26.83396  10.21685  -14.88749 1.000 86.78778  ? 114 GLN B C      1 
ATOM   2776 O  O      . GLN B 1  84  ? 26.80671  10.24649  -16.12382 1.000 87.59079  ? 114 GLN B O      1 
ATOM   2777 C  CB     . GLN B 1  84  ? 28.67471  11.53224  -13.79571 1.000 91.86127  ? 114 GLN B CB     1 
ATOM   2778 C  CG     . GLN B 1  84  ? 29.18846  12.94250  -13.54583 1.000 95.87604  ? 114 GLN B CG     1 
ATOM   2779 C  CD     . GLN B 1  84  ? 30.55974  12.96771  -12.90801 1.000 94.53994  ? 114 GLN B CD     1 
ATOM   2780 O  OE1    . GLN B 1  84  ? 31.27131  11.96073  -12.89286 1.000 98.60451  ? 114 GLN B OE1    1 
ATOM   2781 N  NE2    . GLN B 1  84  ? 30.94720  14.12762  -12.39078 1.000 87.93338  ? 114 GLN B NE2    1 
ATOM   2782 N  N      . ARG B 1  85  ? 26.55801  9.10554   -14.20127 1.000 88.71684  ? 115 ARG B N      1 
ATOM   2783 C  CA     . ARG B 1  85  ? 26.28517  7.86201   -14.91732 1.000 82.01008  ? 115 ARG B CA     1 
ATOM   2784 C  C      . ARG B 1  85  ? 24.91327  7.88335   -15.57694 1.000 77.78355  ? 115 ARG B C      1 
ATOM   2785 O  O      . ARG B 1  85  ? 24.74122  7.33884   -16.67256 1.000 82.50135  ? 115 ARG B O      1 
ATOM   2786 C  CB     . ARG B 1  85  ? 26.37175  6.66416   -13.97891 1.000 78.66193  ? 115 ARG B CB     1 
ATOM   2787 C  CG     . ARG B 1  85  ? 26.14704  5.34378   -14.69719 1.000 77.95325  ? 115 ARG B CG     1 
ATOM   2788 C  CD     . ARG B 1  85  ? 26.05787  4.19962   -13.71360 1.000 85.68497  ? 115 ARG B CD     1 
ATOM   2789 N  NE     . ARG B 1  85  ? 26.93297  4.40487   -12.56711 1.000 93.63208  ? 115 ARG B NE     1 
ATOM   2790 C  CZ     . ARG B 1  85  ? 26.69690  3.92206   -11.35501 1.000 96.64802  ? 115 ARG B CZ     1 
ATOM   2791 N  NH1    . ARG B 1  85  ? 25.62862  3.18252   -11.10202 1.000 94.15194  ? 115 ARG B NH1    1 
ATOM   2792 N  NH2    . ARG B 1  85  ? 27.55662  4.18259   -10.37372 1.000 92.58873  ? 115 ARG B NH2    1 
ATOM   2793 N  N      . HIS B 1  86  ? 23.92001  8.48649   -14.92330 1.000 79.60732  ? 116 HIS B N      1 
ATOM   2794 C  CA     . HIS B 1  86  ? 22.54237  8.40215   -15.39288 1.000 80.72911  ? 116 HIS B CA     1 
ATOM   2795 C  C      . HIS B 1  86  ? 21.97763  9.71006   -15.92992 1.000 77.06380  ? 116 HIS B C      1 
ATOM   2796 O  O      . HIS B 1  86  ? 21.06201  9.67075   -16.75220 1.000 74.39784  ? 116 HIS B O      1 
ATOM   2797 C  CB     . HIS B 1  86  ? 21.63267  7.88498   -14.27146 1.000 78.04902  ? 116 HIS B CB     1 
ATOM   2798 C  CG     . HIS B 1  86  ? 22.00276  6.51850   -13.77902 1.000 76.34287  ? 116 HIS B CG     1 
ATOM   2799 N  ND1    . HIS B 1  86  ? 21.79250  5.37737   -14.52260 1.000 75.44828  ? 116 HIS B ND1    1 
ATOM   2800 C  CD2    . HIS B 1  86  ? 22.56506  6.10979   -12.61594 1.000 81.56985  ? 116 HIS B CD2    1 
ATOM   2801 C  CE1    . HIS B 1  86  ? 22.21325  4.32567   -13.84177 1.000 76.49439  ? 116 HIS B CE1    1 
ATOM   2802 N  NE2    . HIS B 1  86  ? 22.68485  4.74221   -12.68063 1.000 75.43379  ? 116 HIS B NE2    1 
ATOM   2803 N  N      . GLY B 1  87  ? 22.47814  10.86088  -15.48595 1.000 72.89895  ? 117 GLY B N      1 
ATOM   2804 C  CA     . GLY B 1  87  ? 22.01926  12.12592  -16.04315 1.000 69.56718  ? 117 GLY B CA     1 
ATOM   2805 C  C      . GLY B 1  87  ? 20.54589  12.41758  -15.85059 1.000 77.93544  ? 117 GLY B C      1 
ATOM   2806 O  O      . GLY B 1  87  ? 19.95643  13.15267  -16.65306 1.000 79.08083  ? 117 GLY B O      1 
ATOM   2807 N  N      . ASP B 1  88  ? 19.93327  11.88363  -14.78887 1.000 75.32145  ? 118 ASP B N      1 
ATOM   2808 C  CA     . ASP B 1  88  ? 18.49368  12.00217  -14.58031 1.000 67.34684  ? 118 ASP B CA     1 
ATOM   2809 C  C      . ASP B 1  88  ? 18.14204  12.61563  -13.22900 1.000 63.16358  ? 118 ASP B C      1 
ATOM   2810 O  O      . ASP B 1  88  ? 17.01526  12.44266  -12.75409 1.000 66.25734  ? 118 ASP B O      1 
ATOM   2811 C  CB     . ASP B 1  88  ? 17.82457  10.63040  -14.71913 1.000 63.97426  ? 118 ASP B CB     1 
ATOM   2812 C  CG     . ASP B 1  88  ? 18.42963  9.57329   -13.79075 1.000 71.34380  ? 118 ASP B CG     1 
ATOM   2813 O  OD1    . ASP B 1  88  ? 19.26472  9.92259   -12.92872 1.000 67.59426  ? 118 ASP B OD1    1 
ATOM   2814 O  OD2    . ASP B 1  88  ? 18.06615  8.38215   -13.92463 1.000 69.41233  ? 118 ASP B OD2    1 
ATOM   2815 N  N      . ILE B 1  89  ? 19.05790  13.36260  -12.61643 1.000 64.76185  ? 119 ILE B N      1 
ATOM   2816 C  CA     . ILE B 1  89  ? 18.85571  13.93063  -11.28621 1.000 63.11896  ? 119 ILE B CA     1 
ATOM   2817 C  C      . ILE B 1  89  ? 18.63301  15.43432  -11.40249 1.000 62.75877  ? 119 ILE B C      1 
ATOM   2818 O  O      . ILE B 1  89  ? 19.38517  16.12961  -12.09409 1.000 66.22493  ? 119 ILE B O      1 
ATOM   2819 C  CB     . ILE B 1  89  ? 20.04225  13.61236  -10.36112 1.000 61.71858  ? 119 ILE B CB     1 
ATOM   2820 C  CG1    . ILE B 1  89  ? 20.10315  12.10396  -10.10141 1.000 69.41379  ? 119 ILE B CG1    1 
ATOM   2821 C  CG2    . ILE B 1  89  ? 19.90582  14.35869  -9.04878  1.000 65.59265  ? 119 ILE B CG2    1 
ATOM   2822 C  CD1    . ILE B 1  89  ? 21.24486  11.66986  -9.20857  1.000 76.81653  ? 119 ILE B CD1    1 
ATOM   2823 N  N      . ILE B 1  90  ? 17.58808  15.92720  -10.73909 1.000 62.07030  ? 120 ILE B N      1 
ATOM   2824 C  CA     . ILE B 1  90  ? 17.31978  17.35563  -10.58621 1.000 55.73901  ? 120 ILE B CA     1 
ATOM   2825 C  C      . ILE B 1  90  ? 17.65197  17.72777  -9.14807  1.000 66.85552  ? 120 ILE B C      1 
ATOM   2826 O  O      . ILE B 1  90  ? 17.04144  17.20039  -8.20925  1.000 60.46327  ? 120 ILE B O      1 
ATOM   2827 C  CB     . ILE B 1  90  ? 15.85674  17.69288  -10.90339 1.000 60.95311  ? 120 ILE B CB     1 
ATOM   2828 C  CG1    . ILE B 1  90  ? 15.49847  17.24646  -12.32452 1.000 57.65906  ? 120 ILE B CG1    1 
ATOM   2829 C  CG2    . ILE B 1  90  ? 15.58350  19.18423  -10.67111 1.000 51.40597  ? 120 ILE B CG2    1 
ATOM   2830 C  CD1    . ILE B 1  90  ? 14.01129  17.15728  -12.57269 1.000 59.43605  ? 120 ILE B CD1    1 
ATOM   2831 N  N      . GLN B 1  91  ? 18.57528  18.66942  -8.96959  1.000 70.69015  ? 121 GLN B N      1 
ATOM   2832 C  CA     . GLN B 1  91  ? 19.07336  18.99198  -7.64135  1.000 68.38192  ? 121 GLN B CA     1 
ATOM   2833 C  C      . GLN B 1  91  ? 19.18074  20.49712  -7.45533  1.000 70.21556  ? 121 GLN B C      1 
ATOM   2834 O  O      . GLN B 1  91  ? 19.46978  21.23196  -8.40349  1.000 66.31722  ? 121 GLN B O      1 
ATOM   2835 C  CB     . GLN B 1  91  ? 20.44193  18.34472  -7.38498  1.000 66.58418  ? 121 GLN B CB     1 
ATOM   2836 C  CG     . GLN B 1  91  ? 20.95929  18.55589  -5.96935  1.000 71.18698  ? 121 GLN B CG     1 
ATOM   2837 C  CD     . GLN B 1  91  ? 22.35160  17.99938  -5.77624  1.000 75.32785  ? 121 GLN B CD     1 
ATOM   2838 O  OE1    . GLN B 1  91  ? 23.24170  18.22885  -6.59528  1.000 80.46014  ? 121 GLN B OE1    1 
ATOM   2839 N  NE2    . GLN B 1  91  ? 22.54826  17.25703  -4.69125  1.000 74.97600  ? 121 GLN B NE2    1 
ATOM   2840 N  N      . LYS B 1  92  ? 18.90088  20.94200  -6.23002  1.000 70.03563  ? 122 LYS B N      1 
ATOM   2841 C  CA     . LYS B 1  92  ? 19.15507  22.30332  -5.78279  1.000 69.59503  ? 122 LYS B CA     1 
ATOM   2842 C  C      . LYS B 1  92  ? 19.75193  22.23389  -4.38349  1.000 79.40025  ? 122 LYS B C      1 
ATOM   2843 O  O      . LYS B 1  92  ? 19.73601  21.18473  -3.73045  1.000 77.66087  ? 122 LYS B O      1 
ATOM   2844 C  CB     . LYS B 1  92  ? 17.88631  23.16071  -5.80830  1.000 61.36860  ? 122 LYS B CB     1 
ATOM   2845 C  CG     . LYS B 1  92  ? 17.39146  23.45737  -7.20848  1.000 63.57047  ? 122 LYS B CG     1 
ATOM   2846 C  CD     . LYS B 1  92  ? 16.21386  24.42246  -7.21473  1.000 63.32222  ? 122 LYS B CD     1 
ATOM   2847 C  CE     . LYS B 1  92  ? 16.57814  25.78255  -6.64988  1.000 60.74504  ? 122 LYS B CE     1 
ATOM   2848 N  NZ     . LYS B 1  92  ? 15.48707  26.76466  -6.91309  1.000 53.14479  ? 122 LYS B NZ     1 
ATOM   2849 N  N      . ASP B 1  93  ? 20.29259  23.36473  -3.92598  1.000 76.24547  ? 123 ASP B N      1 
ATOM   2850 C  CA     . ASP B 1  93  ? 21.03022  23.42480  -2.66196  1.000 78.63740  ? 123 ASP B CA     1 
ATOM   2851 C  C      . ASP B 1  93  ? 20.05665  23.62888  -1.50197  1.000 81.27966  ? 123 ASP B C      1 
ATOM   2852 O  O      . ASP B 1  93  ? 19.82302  24.74351  -1.02651  1.000 85.59789  ? 123 ASP B O      1 
ATOM   2853 C  CB     . ASP B 1  93  ? 22.06915  24.53869  -2.71101  1.000 84.70760  ? 123 ASP B CB     1 
ATOM   2854 C  CG     . ASP B 1  93  ? 22.99377  24.52860  -1.51150  1.000 88.87289  ? 123 ASP B CG     1 
ATOM   2855 O  OD1    . ASP B 1  93  ? 22.90717  23.58102  -0.70003  1.000 87.33116  ? 123 ASP B OD1    1 
ATOM   2856 O  OD2    . ASP B 1  93  ? 23.79813  25.47633  -1.37532  1.000 85.12158  ? 123 ASP B OD2    1 
ATOM   2857 N  N      . PHE B 1  94  ? 19.47976  22.52239  -1.03300  1.000 76.21498  ? 124 PHE B N      1 
ATOM   2858 C  CA     . PHE B 1  94  ? 18.66807  22.55217  0.17548   1.000 72.42153  ? 124 PHE B CA     1 
ATOM   2859 C  C      . PHE B 1  94  ? 18.86556  21.24638  0.93444   1.000 75.39601  ? 124 PHE B C      1 
ATOM   2860 O  O      . PHE B 1  94  ? 19.01628  20.18152  0.32636   1.000 71.21999  ? 124 PHE B O      1 
ATOM   2861 C  CB     . PHE B 1  94  ? 17.18705  22.80391  -0.14590  1.000 73.54565  ? 124 PHE B CB     1 
ATOM   2862 C  CG     . PHE B 1  94  ? 16.52117  21.68410  -0.89373  1.000 73.39122  ? 124 PHE B CG     1 
ATOM   2863 C  CD1    . PHE B 1  94  ? 16.60741  21.60657  -2.27221  1.000 75.13499  ? 124 PHE B CD1    1 
ATOM   2864 C  CD2    . PHE B 1  94  ? 15.77713  20.73118  -0.21961  1.000 71.10719  ? 124 PHE B CD2    1 
ATOM   2865 C  CE1    . PHE B 1  94  ? 15.99081  20.57988  -2.96213  1.000 70.59631  ? 124 PHE B CE1    1 
ATOM   2866 C  CE2    . PHE B 1  94  ? 15.15548  19.70769  -0.90248  1.000 66.89896  ? 124 PHE B CE2    1 
ATOM   2867 C  CZ     . PHE B 1  94  ? 15.26286  19.63285  -2.27621  1.000 66.91927  ? 124 PHE B CZ     1 
ATOM   2868 N  N      . LEU B 1  95  ? 18.89461  21.34169  2.26554   1.000 77.46551  ? 125 LEU B N      1 
ATOM   2869 C  CA     . LEU B 1  95  ? 19.05971  20.16088  3.10458   1.000 76.81988  ? 125 LEU B CA     1 
ATOM   2870 C  C      . LEU B 1  95  ? 17.96339  19.15016  2.79890   1.000 64.92312  ? 125 LEU B C      1 
ATOM   2871 O  O      . LEU B 1  95  ? 16.78481  19.38980  3.08222   1.000 62.20303  ? 125 LEU B O      1 
ATOM   2872 C  CB     . LEU B 1  95  ? 19.04464  20.54258  4.58737   1.000 78.55263  ? 125 LEU B CB     1 
ATOM   2873 C  CG     . LEU B 1  95  ? 19.26509  19.41177  5.59631   1.000 75.47149  ? 125 LEU B CG     1 
ATOM   2874 C  CD1    . LEU B 1  95  ? 20.62237  18.74428  5.39384   1.000 70.58509  ? 125 LEU B CD1    1 
ATOM   2875 C  CD2    . LEU B 1  95  ? 19.10886  19.91600  7.02746   1.000 80.91980  ? 125 LEU B CD2    1 
ATOM   2876 N  N      . ASP B 1  96  ? 18.34559  18.01099  2.23463   1.000 64.47808  ? 126 ASP B N      1 
ATOM   2877 C  CA     . ASP B 1  96  ? 17.37054  17.01451  1.80242   1.000 66.34921  ? 126 ASP B CA     1 
ATOM   2878 C  C      . ASP B 1  96  ? 16.93234  16.20116  3.01523   1.000 54.36094  ? 126 ASP B C      1 
ATOM   2879 O  O      . ASP B 1  96  ? 17.50197  15.15829  3.33891   1.000 55.57198  ? 126 ASP B O      1 
ATOM   2880 C  CB     . ASP B 1  96  ? 17.95562  16.11976  0.71940   1.000 63.22847  ? 126 ASP B CB     1 
ATOM   2881 C  CG     . ASP B 1  96  ? 16.88721  15.38102  -0.04340  1.000 58.42223  ? 126 ASP B CG     1 
ATOM   2882 O  OD1    . ASP B 1  96  ? 15.75354  15.30765  0.46945   1.000 52.27354  ? 126 ASP B OD1    1 
ATOM   2883 O  OD2    . ASP B 1  96  ? 17.18447  14.86174  -1.13433  1.000 62.80882  ? 126 ASP B OD2    1 
ATOM   2884 N  N      . VAL B 1  97  ? 15.88619  16.67914  3.68568   1.000 57.06194  ? 127 VAL B N      1 
ATOM   2885 C  CA     . VAL B 1  97  ? 15.30655  15.98985  4.82901   1.000 59.35738  ? 127 VAL B CA     1 
ATOM   2886 C  C      . VAL B 1  97  ? 13.79550  16.05823  4.70144   1.000 60.34926  ? 127 VAL B C      1 
ATOM   2887 O  O      . VAL B 1  97  ? 13.24652  16.86817  3.94983   1.000 54.24237  ? 127 VAL B O      1 
ATOM   2888 C  CB     . VAL B 1  97  ? 15.75449  16.59222  6.17426   1.000 61.23866  ? 127 VAL B CB     1 
ATOM   2889 C  CG1    . VAL B 1  97  ? 17.25045  16.38929  6.36398   1.000 57.35747  ? 127 VAL B CG1    1 
ATOM   2890 C  CG2    . VAL B 1  97  ? 15.38131  18.07180  6.23583   1.000 58.36692  ? 127 VAL B CG2    1 
ATOM   2891 N  N      . TYR B 1  98  ? 13.11998  15.20861  5.47165   1.000 52.24479  ? 128 TYR B N      1 
ATOM   2892 C  CA     . TYR B 1  98  ? 11.68311  15.07611  5.29175   1.000 54.07028  ? 128 TYR B CA     1 
ATOM   2893 C  C      . TYR B 1  98  ? 10.99295  16.43133  5.35679   1.000 55.33031  ? 128 TYR B C      1 
ATOM   2894 O  O      . TYR B 1  98  ? 10.16372  16.75676  4.49564   1.000 51.61157  ? 128 TYR B O      1 
ATOM   2895 C  CB     . TYR B 1  98  ? 11.10345  14.11719  6.32997   1.000 51.88292  ? 128 TYR B CB     1 
ATOM   2896 C  CG     . TYR B 1  98  ? 9.70175   13.67486  5.98908   1.000 51.78469  ? 128 TYR B CG     1 
ATOM   2897 C  CD1    . TYR B 1  98  ? 9.48557   12.59601  5.14162   1.000 53.37287  ? 128 TYR B CD1    1 
ATOM   2898 C  CD2    . TYR B 1  98  ? 8.59527   14.34658  6.49153   1.000 52.32232  ? 128 TYR B CD2    1 
ATOM   2899 C  CE1    . TYR B 1  98  ? 8.20723   12.19267  4.81167   1.000 51.14990  ? 128 TYR B CE1    1 
ATOM   2900 C  CE2    . TYR B 1  98  ? 7.31301   13.94889  6.17273   1.000 47.43092  ? 128 TYR B CE2    1 
ATOM   2901 C  CZ     . TYR B 1  98  ? 7.12536   12.86963  5.32701   1.000 49.90830  ? 128 TYR B CZ     1 
ATOM   2902 O  OH     . TYR B 1  98  ? 5.85032   12.46801  5.00077   1.000 47.64965  ? 128 TYR B OH     1 
ATOM   2903 N  N      . TYR B 1  99  ? 11.36481  17.26370  6.32724   1.000 52.40146  ? 129 TYR B N      1 
ATOM   2904 C  CA     . TYR B 1  99  ? 10.64131  18.51164  6.54941   1.000 55.62771  ? 129 TYR B CA     1 
ATOM   2905 C  C      . TYR B 1  99  ? 11.00432  19.59852  5.56078   1.000 52.58486  ? 129 TYR B C      1 
ATOM   2906 O  O      . TYR B 1  99  ? 10.54436  20.73560  5.70438   1.000 52.43809  ? 129 TYR B O      1 
ATOM   2907 C  CB     . TYR B 1  99  ? 10.85397  18.97434  7.98955   1.000 54.67370  ? 129 TYR B CB     1 
ATOM   2908 C  CG     . TYR B 1  99  ? 10.10351  18.05029  8.90874   1.000 64.31049  ? 129 TYR B CG     1 
ATOM   2909 C  CD1    . TYR B 1  99  ? 8.81691   17.63891  8.57946   1.000 61.31749  ? 129 TYR B CD1    1 
ATOM   2910 C  CD2    . TYR B 1  99  ? 10.68613  17.53264  10.05492  1.000 67.07163  ? 129 TYR B CD2    1 
ATOM   2911 C  CE1    . TYR B 1  99  ? 8.11490   16.77748  9.38294   1.000 64.20778  ? 129 TYR B CE1    1 
ATOM   2912 C  CE2    . TYR B 1  99  ? 9.98853   16.65845  10.87143  1.000 69.14915  ? 129 TYR B CE2    1 
ATOM   2913 C  CZ     . TYR B 1  99  ? 8.70175   16.28595  10.52676  1.000 69.86523  ? 129 TYR B CZ     1 
ATOM   2914 O  OH     . TYR B 1  99  ? 7.98525   15.41959  11.31990  1.000 72.66256  ? 129 TYR B OH     1 
ATOM   2915 N  N      . ASN B 1  100 ? 11.77409  19.26103  4.53334   1.000 57.52802  ? 130 ASN B N      1 
ATOM   2916 C  CA     . ASN B 1  100 ? 11.99317  20.15047  3.40583   1.000 56.21538  ? 130 ASN B CA     1 
ATOM   2917 C  C      . ASN B 1  100 ? 11.34419  19.63303  2.13171   1.000 53.07583  ? 130 ASN B C      1 
ATOM   2918 O  O      . ASN B 1  100 ? 11.64626  20.13298  1.04292   1.000 52.58152  ? 130 ASN B O      1 
ATOM   2919 C  CB     . ASN B 1  100 ? 13.48447  20.35533  3.18805   1.000 60.43817  ? 130 ASN B CB     1 
ATOM   2920 C  CG     . ASN B 1  100 ? 13.97529  21.65377  3.76882   1.000 68.03677  ? 130 ASN B CG     1 
ATOM   2921 O  OD1    . ASN B 1  100 ? 13.18983  22.55530  4.08172   1.000 66.49975  ? 130 ASN B OD1    1 
ATOM   2922 N  ND2    . ASN B 1  100 ? 15.28507  21.75894  3.91596   1.000 74.66778  ? 130 ASN B ND2    1 
ATOM   2923 N  N      . LEU B 1  101 ? 10.46963  18.63036  2.24136   1.000 56.00959  ? 131 LEU B N      1 
ATOM   2924 C  CA     . LEU B 1  101 ? 9.82939   18.08514  1.04943   1.000 46.92056  ? 131 LEU B CA     1 
ATOM   2925 C  C      . LEU B 1  101 ? 9.04517   19.14364  0.28128   1.000 43.99769  ? 131 LEU B C      1 
ATOM   2926 O  O      . LEU B 1  101 ? 8.98754   19.08531  -0.95417  1.000 46.68245  ? 131 LEU B O      1 
ATOM   2927 C  CB     . LEU B 1  101 ? 8.93237   16.90677  1.42864   1.000 41.65527  ? 131 LEU B CB     1 
ATOM   2928 C  CG     . LEU B 1  101 ? 9.72978   15.63148  1.67832   1.000 37.97358  ? 131 LEU B CG     1 
ATOM   2929 C  CD1    . LEU B 1  101 ? 8.81016   14.49507  2.08240   1.000 43.76758  ? 131 LEU B CD1    1 
ATOM   2930 C  CD2    . LEU B 1  101 ? 10.56427  15.26025  0.45427   1.000 44.91328  ? 131 LEU B CD2    1 
ATOM   2931 N  N      . THR B 1  102 ? 8.46222   20.13495  0.96419   1.000 41.77597  ? 132 THR B N      1 
ATOM   2932 C  CA     . THR B 1  102 ? 7.78407   21.18635  0.21294   1.000 40.31439  ? 132 THR B CA     1 
ATOM   2933 C  C      . THR B 1  102 ? 8.76373   21.82286  -0.75831  1.000 50.58392  ? 132 THR B C      1 
ATOM   2934 O  O      . THR B 1  102 ? 8.47787   21.95555  -1.95715  1.000 48.70031  ? 132 THR B O      1 
ATOM   2935 C  CB     . THR B 1  102 ? 7.17756   22.23710  1.14225   1.000 41.80593  ? 132 THR B CB     1 
ATOM   2936 O  OG1    . THR B 1  102 ? 6.16331   21.64707  1.96116   1.000 39.23570  ? 132 THR B OG1    1 
ATOM   2937 C  CG2    . THR B 1  102 ? 6.52116   23.35047  0.32096   1.000 39.00436  ? 132 THR B CG2    1 
ATOM   2938 N  N      . LEU B 1  103 ? 9.96789   22.13417  -0.27076  1.000 49.44074  ? 133 LEU B N      1 
ATOM   2939 C  CA     . LEU B 1  103 ? 11.00371  22.66089  -1.14958  1.000 53.14084  ? 133 LEU B CA     1 
ATOM   2940 C  C      . LEU B 1  103 ? 11.25140  21.70510  -2.30756  1.000 47.94333  ? 133 LEU B C      1 
ATOM   2941 O  O      . LEU B 1  103 ? 11.21138  22.10500  -3.48047  1.000 47.32544  ? 133 LEU B O      1 
ATOM   2942 C  CB     . LEU B 1  103 ? 12.29145  22.90179  -0.35659  1.000 55.88993  ? 133 LEU B CB     1 
ATOM   2943 C  CG     . LEU B 1  103 ? 12.16620  23.83354  0.86120   1.000 54.33709  ? 133 LEU B CG     1 
ATOM   2944 C  CD1    . LEU B 1  103 ? 13.52782  24.13445  1.49109   1.000 57.86127  ? 133 LEU B CD1    1 
ATOM   2945 C  CD2    . LEU B 1  103 ? 11.41291  25.10639  0.53140   1.000 49.68739  ? 133 LEU B CD2    1 
ATOM   2946 N  N      . LYS B 1  104 ? 11.41847  20.41523  -2.00497  1.000 44.42747  ? 134 LYS B N      1 
ATOM   2947 C  CA     . LYS B 1  104 ? 11.66647  19.46480  -3.07915  1.000 41.79817  ? 134 LYS B CA     1 
ATOM   2948 C  C      . LYS B 1  104 ? 10.53523  19.51275  -4.09261  1.000 40.52159  ? 134 LYS B C      1 
ATOM   2949 O  O      . LYS B 1  104 ? 10.77312  19.65170  -5.29808  1.000 45.81324  ? 134 LYS B O      1 
ATOM   2950 C  CB     . LYS B 1  104 ? 11.84463  18.04998  -2.53128  1.000 47.91849  ? 134 LYS B CB     1 
ATOM   2951 C  CG     . LYS B 1  104 ? 12.14858  17.04360  -3.62528  1.000 41.22654  ? 134 LYS B CG     1 
ATOM   2952 C  CD     . LYS B 1  104 ? 12.59095  15.71883  -3.07425  1.000 52.13101  ? 134 LYS B CD     1 
ATOM   2953 C  CE     . LYS B 1  104 ? 13.99837  15.80461  -2.51532  1.000 55.24851  ? 134 LYS B CE     1 
ATOM   2954 N  NZ     . LYS B 1  104 ? 14.60910  14.45230  -2.41364  1.000 56.33802  ? 134 LYS B NZ     1 
ATOM   2955 N  N      . THR B 1  105 ? 9.28836   19.48257  -3.61756  1.000 39.09857  ? 135 THR B N      1 
ATOM   2956 C  CA     . THR B 1  105 ? 8.18445   19.52035  -4.56580  1.000 40.51722  ? 135 THR B CA     1 
ATOM   2957 C  C      . THR B 1  105 ? 8.24137   20.80143  -5.38399  1.000 46.94841  ? 135 THR B C      1 
ATOM   2958 O  O      . THR B 1  105 ? 8.18001   20.76887  -6.62379  1.000 40.43862  ? 135 THR B O      1 
ATOM   2959 C  CB     . THR B 1  105 ? 6.85128   19.37632  -3.83760  1.000 31.56837  ? 135 THR B CB     1 
ATOM   2960 O  OG1    . THR B 1  105 ? 6.65975   17.99740  -3.48425  1.000 35.78584  ? 135 THR B OG1    1 
ATOM   2961 C  CG2    . THR B 1  105 ? 5.69374   19.84657  -4.71492  1.000 33.19625  ? 135 THR B CG2    1 
ATOM   2962 N  N      . MET B 1  106 ? 8.45171   21.93989  -4.71501  1.000 41.92965  ? 136 MET B N      1 
ATOM   2963 C  CA     . MET B 1  106 ? 8.48911   23.18170  -5.47675  1.000 39.12262  ? 136 MET B CA     1 
ATOM   2964 C  C      . MET B 1  106 ? 9.67721   23.19174  -6.42495  1.000 39.98088  ? 136 MET B C      1 
ATOM   2965 O  O      . MET B 1  106 ? 9.54968   23.65555  -7.56740  1.000 49.63262  ? 136 MET B O      1 
ATOM   2966 C  CB     . MET B 1  106 ? 8.50008   24.39016  -4.54679  1.000 45.79175  ? 136 MET B CB     1 
ATOM   2967 C  CG     . MET B 1  106 ? 7.14012   24.69242  -3.90941  1.000 38.14280  ? 136 MET B CG     1 
ATOM   2968 S  SD     . MET B 1  106 ? 5.75709   24.78522  -5.07822  1.000 46.89280  ? 136 MET B SD     1 
ATOM   2969 C  CE     . MET B 1  106 ? 6.41380   25.97227  -6.25325  1.000 47.90064  ? 136 MET B CE     1 
ATOM   2970 N  N      . MET B 1  107 ? 10.80022  22.58523  -6.02476  1.000 39.46703  ? 137 MET B N      1 
ATOM   2971 C  CA     . MET B 1  107 ? 11.90297  22.48146  -6.96914  1.000 45.00337  ? 137 MET B CA     1 
ATOM   2972 C  C      . MET B 1  107 ? 11.41895  21.81497  -8.24401  1.000 50.99756  ? 137 MET B C      1 
ATOM   2973 O  O      . MET B 1  107 ? 11.52468  22.38286  -9.33684  1.000 50.48091  ? 137 MET B O      1 
ATOM   2974 C  CB     . MET B 1  107 ? 13.06450  21.69443  -6.36863  1.000 46.22437  ? 137 MET B CB     1 
ATOM   2975 C  CG     . MET B 1  107 ? 14.13847  21.32796  -7.38828  1.000 48.27618  ? 137 MET B CG     1 
ATOM   2976 S  SD     . MET B 1  107 ? 15.50705  20.38613  -6.70051  1.000 56.71414  ? 137 MET B SD     1 
ATOM   2977 C  CE     . MET B 1  107 ? 14.71859  18.81166  -6.35201  1.000 54.78338  ? 137 MET B CE     1 
ATOM   2978 N  N      . GLY B 1  108 ? 10.78137  20.65010  -8.10404  1.000 47.01221  ? 138 GLY B N      1 
ATOM   2979 C  CA     . GLY B 1  108 ? 10.30283  19.95449  -9.28239  1.000 41.31128  ? 138 GLY B CA     1 
ATOM   2980 C  C      . GLY B 1  108 ? 9.35313   20.81760  -10.08302 1.000 46.64013  ? 138 GLY B C      1 
ATOM   2981 O  O      . GLY B 1  108 ? 9.47756   20.94032  -11.30481 1.000 53.26980  ? 138 GLY B O      1 
ATOM   2982 N  N      . ILE B 1  109 ? 8.41634   21.47122  -9.39587  1.000 45.58433  ? 139 ILE B N      1 
ATOM   2983 C  CA     . ILE B 1  109 ? 7.45304   22.28092  -10.12193 1.000 47.50712  ? 139 ILE B CA     1 
ATOM   2984 C  C      . ILE B 1  109 ? 8.17906   23.40699  -10.83425 1.000 55.30057  ? 139 ILE B C      1 
ATOM   2985 O  O      . ILE B 1  109 ? 7.97004   23.64095  -12.03417 1.000 50.78408  ? 139 ILE B O      1 
ATOM   2986 C  CB     . ILE B 1  109 ? 6.35255   22.78541  -9.17166  1.000 50.52592  ? 139 ILE B CB     1 
ATOM   2987 C  CG1    . ILE B 1  109 ? 5.37760   21.64635  -8.87245  1.000 45.58124  ? 139 ILE B CG1    1 
ATOM   2988 C  CG2    . ILE B 1  109 ? 5.61797   23.98024  -9.76270  1.000 45.10878  ? 139 ILE B CG2    1 
ATOM   2989 C  CD1    . ILE B 1  109 ? 4.50077   21.88261  -7.67711  1.000 43.27746  ? 139 ILE B CD1    1 
ATOM   2990 N  N      . GLU B 1  110 ? 9.13535   24.03754  -10.14452 1.000 55.87691  ? 140 GLU B N      1 
ATOM   2991 C  CA     . GLU B 1  110 ? 9.90293   25.08829  -10.79455 1.000 55.22104  ? 140 GLU B CA     1 
ATOM   2992 C  C      . GLU B 1  110 ? 10.54864  24.55288  -12.06062 1.000 54.06776  ? 140 GLU B C      1 
ATOM   2993 O  O      . GLU B 1  110 ? 10.46765  25.18405  -13.12129 1.000 56.71259  ? 140 GLU B O      1 
ATOM   2994 C  CB     . GLU B 1  110 ? 10.95862  25.64673  -9.83843  1.000 56.02589  ? 140 GLU B CB     1 
ATOM   2995 C  CG     . GLU B 1  110 ? 11.80315  26.77613  -10.42361 1.000 62.73445  ? 140 GLU B CG     1 
ATOM   2996 C  CD     . GLU B 1  110 ? 12.94304  27.20299  -9.50444  1.000 71.60481  ? 140 GLU B CD     1 
ATOM   2997 O  OE1    . GLU B 1  110 ? 13.03510  26.66952  -8.37670  1.000 70.51145  ? 140 GLU B OE1    1 
ATOM   2998 O  OE2    . GLU B 1  110 ? 13.74900  28.07142  -9.90992  1.000 75.48675  ? 140 GLU B OE2    1 
ATOM   2999 N  N      . TRP B 1  111 ? 11.11856  23.34595  -11.99042 1.000 55.58687  ? 141 TRP B N      1 
ATOM   3000 C  CA     . TRP B 1  111 ? 11.78000  22.79477  -13.16538 1.000 58.11986  ? 141 TRP B CA     1 
ATOM   3001 C  C      . TRP B 1  111 ? 10.79212  22.67134  -14.31735 1.000 58.76094  ? 141 TRP B C      1 
ATOM   3002 O  O      . TRP B 1  111 ? 11.04249  23.17262  -15.42150 1.000 59.69088  ? 141 TRP B O      1 
ATOM   3003 C  CB     . TRP B 1  111 ? 12.41594  21.44582  -12.82995 1.000 59.97015  ? 141 TRP B CB     1 
ATOM   3004 C  CG     . TRP B 1  111 ? 13.19929  20.84201  -13.95654 1.000 64.03347  ? 141 TRP B CG     1 
ATOM   3005 C  CD1    . TRP B 1  111 ? 14.52102  21.04897  -14.24178 1.000 64.63736  ? 141 TRP B CD1    1 
ATOM   3006 C  CD2    . TRP B 1  111 ? 12.71043  19.93875  -14.95517 1.000 62.20381  ? 141 TRP B CD2    1 
ATOM   3007 N  NE1    . TRP B 1  111 ? 14.88671  20.32147  -15.34919 1.000 59.67186  ? 141 TRP B NE1    1 
ATOM   3008 C  CE2    . TRP B 1  111 ? 13.79316  19.63197  -15.80697 1.000 66.55230  ? 141 TRP B CE2    1 
ATOM   3009 C  CE3    . TRP B 1  111 ? 11.46532  19.35356  -15.20783 1.000 59.15606  ? 141 TRP B CE3    1 
ATOM   3010 C  CZ2    . TRP B 1  111 ? 13.66601  18.76678  -16.89404 1.000 65.78399  ? 141 TRP B CZ2    1 
ATOM   3011 C  CZ3    . TRP B 1  111 ? 11.34242  18.49563  -16.28618 1.000 60.13368  ? 141 TRP B CZ3    1 
ATOM   3012 C  CH2    . TRP B 1  111 ? 12.43559  18.21235  -17.11747 1.000 62.28397  ? 141 TRP B CH2    1 
ATOM   3013 N  N      . VAL B 1  112 ? 9.62208   22.07721  -14.05831 1.000 53.11290  ? 142 VAL B N      1 
ATOM   3014 C  CA     . VAL B 1  112 ? 8.63653   21.96538  -15.12944 1.000 53.16840  ? 142 VAL B CA     1 
ATOM   3015 C  C      . VAL B 1  112 ? 8.32569   23.34621  -15.68419 1.000 55.24451  ? 142 VAL B C      1 
ATOM   3016 O  O      . VAL B 1  112 ? 8.23251   23.54143  -16.90291 1.000 47.50622  ? 142 VAL B O      1 
ATOM   3017 C  CB     . VAL B 1  112 ? 7.36133   21.25296  -14.64284 1.000 49.79884  ? 142 VAL B CB     1 
ATOM   3018 C  CG1    . VAL B 1  112 ? 6.31661   21.23806  -15.75373 1.000 47.82689  ? 142 VAL B CG1    1 
ATOM   3019 C  CG2    . VAL B 1  112 ? 7.68613   19.83625  -14.19025 1.000 43.42465  ? 142 VAL B CG2    1 
ATOM   3020 N  N      . HIS B 1  113 ? 8.15373   24.32534  -14.79522 1.000 53.56246  ? 143 HIS B N      1 
ATOM   3021 C  CA     . HIS B 1  113 ? 7.82318   25.67278  -15.24214 1.000 56.46027  ? 143 HIS B CA     1 
ATOM   3022 C  C      . HIS B 1  113 ? 8.93544   26.25351  -16.10876 1.000 60.30431  ? 143 HIS B C      1 
ATOM   3023 O  O      . HIS B 1  113 ? 8.66341   26.94422  -17.09692 1.000 56.44260  ? 143 HIS B O      1 
ATOM   3024 C  CB     . HIS B 1  113 ? 7.54471   26.56921  -14.03988 1.000 61.55947  ? 143 HIS B CB     1 
ATOM   3025 C  CG     . HIS B 1  113 ? 7.42401   28.01953  -14.38169 1.000 58.24876  ? 143 HIS B CG     1 
ATOM   3026 N  ND1    . HIS B 1  113 ? 6.42491   28.50716  -15.19591 1.000 58.95369  ? 143 HIS B ND1    1 
ATOM   3027 C  CD2    . HIS B 1  113 ? 8.16520   29.08976  -14.00876 1.000 58.98328  ? 143 HIS B CD2    1 
ATOM   3028 C  CE1    . HIS B 1  113 ? 6.55623   29.81691  -15.31154 1.000 63.03571  ? 143 HIS B CE1    1 
ATOM   3029 N  NE2    . HIS B 1  113 ? 7.60416   30.19583  -14.60059 1.000 58.60664  ? 143 HIS B NE2    1 
ATOM   3030 N  N      . ARG B 1  114 ? 10.19561  26.01615  -15.73573 1.000 59.66447  ? 144 ARG B N      1 
ATOM   3031 C  CA     . ARG B 1  114 ? 11.28519  26.68476  -16.43514 1.000 65.94340  ? 144 ARG B CA     1 
ATOM   3032 C  C      . ARG B 1  114 ? 11.74303  25.92140  -17.66762 1.000 63.01423  ? 144 ARG B C      1 
ATOM   3033 O  O      . ARG B 1  114 ? 12.00212  26.52743  -18.71142 1.000 64.03687  ? 144 ARG B O      1 
ATOM   3034 C  CB     . ARG B 1  114 ? 12.49438  26.87325  -15.51464 1.000 63.30041  ? 144 ARG B CB     1 
ATOM   3035 C  CG     . ARG B 1  114 ? 12.27510  27.80112  -14.34672 1.000 59.81084  ? 144 ARG B CG     1 
ATOM   3036 C  CD     . ARG B 1  114 ? 13.60158  28.09369  -13.66540 1.000 70.91962  ? 144 ARG B CD     1 
ATOM   3037 N  NE     . ARG B 1  114 ? 13.42424  28.82320  -12.41722 1.000 75.58542  ? 144 ARG B NE     1 
ATOM   3038 C  CZ     . ARG B 1  114 ? 13.12337  30.11067  -12.33414 1.000 76.09536  ? 144 ARG B CZ     1 
ATOM   3039 N  NH1    . ARG B 1  114 ? 13.06073  30.87591  -13.41129 1.000 68.07763  ? 144 ARG B NH1    1 
ATOM   3040 N  NH2    . ARG B 1  114 ? 12.92077  30.65198  -11.13548 1.000 78.73261  ? 144 ARG B NH2    1 
ATOM   3041 N  N      . PHE B 1  115 ? 11.83546  24.59928  -17.57671 1.000 59.22822  ? 145 PHE B N      1 
ATOM   3042 C  CA     . PHE B 1  115 ? 12.52074  23.82748  -18.59708 1.000 62.58893  ? 145 PHE B CA     1 
ATOM   3043 C  C      . PHE B 1  115 ? 11.64192  22.82006  -19.32150 1.000 59.87541  ? 145 PHE B C      1 
ATOM   3044 O  O      . PHE B 1  115 ? 12.09947  22.23440  -20.30763 1.000 59.89319  ? 145 PHE B O      1 
ATOM   3045 C  CB     . PHE B 1  115 ? 13.72931  23.10857  -17.98329 1.000 61.34632  ? 145 PHE B CB     1 
ATOM   3046 C  CG     . PHE B 1  115 ? 14.62906  24.02612  -17.20812 1.000 71.82830  ? 145 PHE B CG     1 
ATOM   3047 C  CD1    . PHE B 1  115 ? 15.36263  25.00800  -17.85326 1.000 73.34551  ? 145 PHE B CD1    1 
ATOM   3048 C  CD2    . PHE B 1  115 ? 14.73774  23.91192  -15.82974 1.000 67.86522  ? 145 PHE B CD2    1 
ATOM   3049 C  CE1    . PHE B 1  115 ? 16.18445  25.86517  -17.13711 1.000 76.02105  ? 145 PHE B CE1    1 
ATOM   3050 C  CE2    . PHE B 1  115 ? 15.56199  24.75881  -15.11040 1.000 70.99185  ? 145 PHE B CE2    1 
ATOM   3051 C  CZ     . PHE B 1  115 ? 16.28668  25.73750  -15.76505 1.000 73.88691  ? 145 PHE B CZ     1 
ATOM   3052 N  N      . CYS B 1  116 ? 10.41948  22.57434  -18.86115 1.000 56.19459  ? 146 CYS B N      1 
ATOM   3053 C  CA     . CYS B 1  116 ? 9.60395   21.61872  -19.59417 1.000 50.22672  ? 146 CYS B CA     1 
ATOM   3054 C  C      . CYS B 1  116 ? 8.12528   21.98990  -19.54408 1.000 59.59398  ? 146 CYS B C      1 
ATOM   3055 O  O      . CYS B 1  116 ? 7.28236   21.12644  -19.25969 1.000 56.17202  ? 146 CYS B O      1 
ATOM   3056 C  CB     . CYS B 1  116 ? 9.82237   20.21397  -19.03168 1.000 60.79007  ? 146 CYS B CB     1 
ATOM   3057 S  SG     . CYS B 1  116 ? 9.47623   18.86972  -20.19327 1.000 67.99505  ? 146 CYS B SG     1 
ATOM   3058 N  N      . PRO B 1  117 ? 7.76242   23.24675  -19.83037 1.000 53.72759  ? 147 PRO B N      1 
ATOM   3059 C  CA     . PRO B 1  117 ? 6.33709   23.61903  -19.83892 1.000 48.07490  ? 147 PRO B CA     1 
ATOM   3060 C  C      . PRO B 1  117 ? 5.55106   22.98659  -20.96985 1.000 52.12067  ? 147 PRO B C      1 
ATOM   3061 O  O      . PRO B 1  117 ? 4.31661   23.11676  -21.00090 1.000 48.95510  ? 147 PRO B O      1 
ATOM   3062 C  CB     . PRO B 1  117 ? 6.38144   25.14551  -19.97183 1.000 52.38627  ? 147 PRO B CB     1 
ATOM   3063 C  CG     . PRO B 1  117 ? 7.64064   25.38585  -20.75625 1.000 48.29085  ? 147 PRO B CG     1 
ATOM   3064 C  CD     . PRO B 1  117 ? 8.62258   24.39824  -20.17140 1.000 56.36007  ? 147 PRO B CD     1 
ATOM   3065 N  N      . GLN B 1  118 ? 6.22449   22.32959  -21.90823 1.000 53.74565  ? 148 GLN B N      1 
ATOM   3066 C  CA     . GLN B 1  118 ? 5.55288   21.63857  -22.99803 1.000 55.43864  ? 148 GLN B CA     1 
ATOM   3067 C  C      . GLN B 1  118 ? 4.97334   20.29760  -22.56445 1.000 56.85790  ? 148 GLN B C      1 
ATOM   3068 O  O      . GLN B 1  118 ? 4.17281   19.71804  -23.30607 1.000 51.86307  ? 148 GLN B O      1 
ATOM   3069 C  CB     . GLN B 1  118 ? 6.53331   21.43723  -24.15897 1.000 59.19511  ? 148 GLN B CB     1 
ATOM   3070 C  CG     . GLN B 1  118 ? 7.11280   22.73886  -24.70503 1.000 53.46876  ? 148 GLN B CG     1 
ATOM   3071 C  CD     . GLN B 1  118 ? 8.31079   23.22101  -23.90455 1.000 66.13650  ? 148 GLN B CD     1 
ATOM   3072 O  OE1    . GLN B 1  118 ? 8.72011   22.58167  -22.93192 1.000 60.22439  ? 148 GLN B OE1    1 
ATOM   3073 N  NE2    . GLN B 1  118 ? 8.87327   24.35892  -24.30319 1.000 64.57388  ? 148 GLN B NE2    1 
ATOM   3074 N  N      . ALA B 1  119 ? 5.37049   19.78882  -21.39639 1.000 54.82237  ? 149 ALA B N      1 
ATOM   3075 C  CA     . ALA B 1  119 ? 4.87452   18.50226  -20.92316 1.000 45.76292  ? 149 ALA B CA     1 
ATOM   3076 C  C      . ALA B 1  119 ? 3.35441   18.50792  -20.86056 1.000 44.48114  ? 149 ALA B C      1 
ATOM   3077 O  O      . ALA B 1  119 ? 2.74830   19.38175  -20.23622 1.000 45.14919  ? 149 ALA B O      1 
ATOM   3078 C  CB     . ALA B 1  119 ? 5.46905   18.18160  -19.54719 1.000 50.51218  ? 149 ALA B CB     1 
ATOM   3079 N  N      . ALA B 1  120 ? 2.73105   17.51932  -21.50232 1.000 43.03306  ? 150 ALA B N      1 
ATOM   3080 C  CA     . ALA B 1  120 ? 1.27940   17.43802  -21.43060 1.000 44.06228  ? 150 ALA B CA     1 
ATOM   3081 C  C      . ALA B 1  120 ? 0.83054   17.14056  -20.00765 1.000 38.52240  ? 150 ALA B C      1 
ATOM   3082 O  O      . ALA B 1  120 ? -0.15671  17.71494  -19.53031 1.000 37.56816  ? 150 ALA B O      1 
ATOM   3083 C  CB     . ALA B 1  120 ? 0.75044   16.38023  -22.40013 1.000 42.64289  ? 150 ALA B CB     1 
ATOM   3084 N  N      . PHE B 1  121 ? 1.53003   16.23222  -19.32631 1.000 45.24548  ? 151 PHE B N      1 
ATOM   3085 C  CA     . PHE B 1  121 ? 1.17589   15.84988  -17.96882 1.000 41.82245  ? 151 PHE B CA     1 
ATOM   3086 C  C      . PHE B 1  121 ? 2.43233   15.59498  -17.14882 1.000 39.87880  ? 151 PHE B C      1 
ATOM   3087 O  O      . PHE B 1  121 ? 3.47821   15.19058  -17.66999 1.000 44.86029  ? 151 PHE B O      1 
ATOM   3088 C  CB     . PHE B 1  121 ? 0.24752   14.62219  -17.96860 1.000 38.38738  ? 151 PHE B CB     1 
ATOM   3089 C  CG     . PHE B 1  121 ? -1.06499  14.87212  -18.64773 1.000 33.12799  ? 151 PHE B CG     1 
ATOM   3090 C  CD1    . PHE B 1  121 ? -2.09921  15.50371  -17.97824 1.000 37.85008  ? 151 PHE B CD1    1 
ATOM   3091 C  CD2    . PHE B 1  121 ? -1.25746  14.50944  -19.97350 1.000 40.04243  ? 151 PHE B CD2    1 
ATOM   3092 C  CE1    . PHE B 1  121 ? -3.30603  15.76081  -18.60852 1.000 41.27753  ? 151 PHE B CE1    1 
ATOM   3093 C  CE2    . PHE B 1  121 ? -2.46399  14.75683  -20.61254 1.000 37.99573  ? 151 PHE B CE2    1 
ATOM   3094 C  CZ     . PHE B 1  121 ? -3.49102  15.38021  -19.93603 1.000 40.77161  ? 151 PHE B CZ     1 
ATOM   3095 N  N      . VAL B 1  122 ? 2.31250   15.84152  -15.84635 1.000 35.14408  ? 152 VAL B N      1 
ATOM   3096 C  CA     . VAL B 1  122 ? 3.40327   15.66766  -14.89842 1.000 34.72625  ? 152 VAL B CA     1 
ATOM   3097 C  C      . VAL B 1  122 ? 2.85633   14.88065  -13.72088 1.000 31.45519  ? 152 VAL B C      1 
ATOM   3098 O  O      . VAL B 1  122 ? 1.76971   15.18836  -13.21854 1.000 36.57588  ? 152 VAL B O      1 
ATOM   3099 C  CB     . VAL B 1  122 ? 3.96587   17.01718  -14.40772 1.000 33.18934  ? 152 VAL B CB     1 
ATOM   3100 C  CG1    . VAL B 1  122 ? 5.12252   16.79724  -13.42094 1.000 31.39689  ? 152 VAL B CG1    1 
ATOM   3101 C  CG2    . VAL B 1  122 ? 4.40586   17.87431  -15.57653 1.000 41.75299  ? 152 VAL B CG2    1 
ATOM   3102 N  N      . MET B 1  123 ? 3.59203   13.86644  -13.29267 1.000 36.66429  ? 153 MET B N      1 
ATOM   3103 C  CA     . MET B 1  123 ? 3.27190   13.12440  -12.08153 1.000 37.10054  ? 153 MET B CA     1 
ATOM   3104 C  C      . MET B 1  123 ? 4.42012   13.26943  -11.09520 1.000 39.68934  ? 153 MET B C      1 
ATOM   3105 O  O      . MET B 1  123 ? 5.56540   12.94945  -11.42267 1.000 35.52221  ? 153 MET B O      1 
ATOM   3106 C  CB     . MET B 1  123 ? 3.01085   11.65225  -12.37288 1.000 34.06865  ? 153 MET B CB     1 
ATOM   3107 C  CG     . MET B 1  123 ? 2.82672   10.84978  -11.10325 1.000 36.48202  ? 153 MET B CG     1 
ATOM   3108 S  SD     . MET B 1  123 ? 2.23012   9.18229   -11.40706 1.000 40.20368  ? 153 MET B SD     1 
ATOM   3109 C  CE     . MET B 1  123 ? 1.80020   8.70340   -9.73254  1.000 36.10376  ? 153 MET B CE     1 
ATOM   3110 N  N      . LYS B 1  124 ? 4.10959   13.75232  -9.89702  1.000 32.15409  ? 154 LYS B N      1 
ATOM   3111 C  CA     . LYS B 1  124 ? 5.05524   13.75722  -8.78586  1.000 33.58696  ? 154 LYS B CA     1 
ATOM   3112 C  C      . LYS B 1  124 ? 4.74930   12.55870  -7.89724  1.000 30.14820  ? 154 LYS B C      1 
ATOM   3113 O  O      . LYS B 1  124 ? 3.60480   12.39250  -7.46188  1.000 35.46831  ? 154 LYS B O      1 
ATOM   3114 C  CB     . LYS B 1  124 ? 4.95574   15.06208  -7.99832  1.000 32.34618  ? 154 LYS B CB     1 
ATOM   3115 C  CG     . LYS B 1  124 ? 5.84953   15.12333  -6.76303  1.000 38.42683  ? 154 LYS B CG     1 
ATOM   3116 C  CD     . LYS B 1  124 ? 4.99041   14.87528  -5.54320  1.000 40.88062  ? 154 LYS B CD     1 
ATOM   3117 C  CE     . LYS B 1  124 ? 5.78383   14.37385  -4.37042  1.000 36.52185  ? 154 LYS B CE     1 
ATOM   3118 N  NZ     . LYS B 1  124 ? 4.84244   14.00702  -3.29486  1.000 42.31829  ? 154 LYS B NZ     1 
ATOM   3119 N  N      . THR B 1  125 ? 5.76918   11.73942  -7.62552  1.000 33.27814  ? 155 THR B N      1 
ATOM   3120 C  CA     . THR B 1  125 ? 5.56763   10.46598  -6.93962  1.000 41.98429  ? 155 THR B CA     1 
ATOM   3121 C  C      . THR B 1  125 ? 6.70563   10.15989  -5.96319  1.000 35.02641  ? 155 THR B C      1 
ATOM   3122 O  O      . THR B 1  125 ? 7.83549   10.62971  -6.12415  1.000 39.68931  ? 155 THR B O      1 
ATOM   3123 C  CB     . THR B 1  125 ? 5.43319   9.30597   -7.95577  1.000 35.20498  ? 155 THR B CB     1 
ATOM   3124 O  OG1    . THR B 1  125 ? 5.04311   8.10088   -7.28546  1.000 40.47817  ? 155 THR B OG1    1 
ATOM   3125 C  CG2    . THR B 1  125 ? 6.75907   9.06426   -8.66678  1.000 38.40724  ? 155 THR B CG2    1 
ATOM   3126 N  N      . ASP B 1  126 ? 6.37775   9.34557   -4.95439  1.000 37.49606  ? 156 ASP B N      1 
ATOM   3127 C  CA     . ASP B 1  126 ? 7.32171   8.75220   -4.01568  1.000 39.74834  ? 156 ASP B CA     1 
ATOM   3128 C  C      . ASP B 1  126 ? 8.18728   7.69316   -4.70285  1.000 42.15988  ? 156 ASP B C      1 
ATOM   3129 O  O      . ASP B 1  126 ? 7.90804   7.24583   -5.81580  1.000 40.62002  ? 156 ASP B O      1 
ATOM   3130 C  CB     . ASP B 1  126 ? 6.57774   8.07980   -2.86160  1.000 48.50220  ? 156 ASP B CB     1 
ATOM   3131 C  CG     . ASP B 1  126 ? 6.23478   9.03145   -1.72427  1.000 50.53344  ? 156 ASP B CG     1 
ATOM   3132 O  OD1    . ASP B 1  126 ? 6.11997   10.25426  -1.94313  1.000 42.59827  ? 156 ASP B OD1    1 
ATOM   3133 O  OD2    . ASP B 1  126 ? 6.05846   8.52484   -0.59698  1.000 52.18268  ? 156 ASP B OD2    1 
ATOM   3134 N  N      . SER B 1  127 ? 9.23094   7.24415   -3.99743  1.000 43.72719  ? 157 SER B N      1 
ATOM   3135 C  CA     . SER B 1  127 ? 10.11802  6.22427   -4.55028  1.000 38.49936  ? 157 SER B CA     1 
ATOM   3136 C  C      . SER B 1  127 ? 9.68694   4.80316   -4.21174  1.000 44.31848  ? 157 SER B C      1 
ATOM   3137 O  O      . SER B 1  127 ? 10.04044  3.86948   -4.94227  1.000 45.36445  ? 157 SER B O      1 
ATOM   3138 C  CB     . SER B 1  127 ? 11.54715  6.42329   -4.05103  1.000 47.43502  ? 157 SER B CB     1 
ATOM   3139 O  OG     . SER B 1  127 ? 11.58333  6.47642   -2.63664  1.000 44.04798  ? 157 SER B OG     1 
ATOM   3140 N  N      . ASP B 1  128 ? 8.94869   4.60406   -3.12320  1.000 42.70393  ? 158 ASP B N      1 
ATOM   3141 C  CA     . ASP B 1  128 ? 8.47327   3.26583   -2.76607  1.000 47.43517  ? 158 ASP B CA     1 
ATOM   3142 C  C      . ASP B 1  128 ? 7.10262   3.01452   -3.39605  1.000 39.24844  ? 158 ASP B C      1 
ATOM   3143 O  O      . ASP B 1  128 ? 6.09715   2.77234   -2.72455  1.000 35.95815  ? 158 ASP B O      1 
ATOM   3144 C  CB     . ASP B 1  128 ? 8.44477   3.08905   -1.25153  1.000 44.48692  ? 158 ASP B CB     1 
ATOM   3145 C  CG     . ASP B 1  128 ? 7.66854   4.17732   -0.55936  1.000 45.24893  ? 158 ASP B CG     1 
ATOM   3146 O  OD1    . ASP B 1  128 ? 7.60458   5.29860   -1.11443  1.000 46.24962  ? 158 ASP B OD1    1 
ATOM   3147 O  OD2    . ASP B 1  128 ? 7.09820   3.90681   0.51850   1.000 47.62175  ? 158 ASP B OD2    1 
ATOM   3148 N  N      . MET B 1  129 ? 7.09187   3.07849   -4.72820  1.000 37.70337  ? 159 MET B N      1 
ATOM   3149 C  CA     . MET B 1  129 ? 5.86790   3.06877   -5.51047  1.000 36.46516  ? 159 MET B CA     1 
ATOM   3150 C  C      . MET B 1  129 ? 5.98621   2.12282   -6.69772  1.000 40.57448  ? 159 MET B C      1 
ATOM   3151 O  O      . MET B 1  129 ? 7.07030   1.90507   -7.24252  1.000 42.48174  ? 159 MET B O      1 
ATOM   3152 C  CB     . MET B 1  129 ? 5.54368   4.47166   -6.04031  1.000 37.11960  ? 159 MET B CB     1 
ATOM   3153 C  CG     . MET B 1  129 ? 5.23887   5.52176   -4.98277  1.000 36.59576  ? 159 MET B CG     1 
ATOM   3154 S  SD     . MET B 1  129 ? 3.62509   5.37749   -4.20930  1.000 39.53441  ? 159 MET B SD     1 
ATOM   3155 C  CE     . MET B 1  129 ? 2.50247   5.85203   -5.53874  1.000 37.44183  ? 159 MET B CE     1 
ATOM   3156 N  N      . PHE B 1  130 ? 4.85178   1.56678   -7.09466  1.000 36.30419  ? 160 PHE B N      1 
ATOM   3157 C  CA     . PHE B 1  130 ? 4.68531   0.97201   -8.40987  1.000 39.89939  ? 160 PHE B CA     1 
ATOM   3158 C  C      . PHE B 1  130 ? 3.80272   1.91698   -9.20391  1.000 34.83159  ? 160 PHE B C      1 
ATOM   3159 O  O      . PHE B 1  130 ? 2.73601   2.31171   -8.72336  1.000 32.45065  ? 160 PHE B O      1 
ATOM   3160 C  CB     . PHE B 1  130 ? 4.03686   -0.41145  -8.34117  1.000 37.50855  ? 160 PHE B CB     1 
ATOM   3161 C  CG     . PHE B 1  130 ? 3.53505   -0.91664  -9.68046  1.000 36.60966  ? 160 PHE B CG     1 
ATOM   3162 C  CD1    . PHE B 1  130 ? 4.37952   -1.60127  -10.54150 1.000 41.27561  ? 160 PHE B CD1    1 
ATOM   3163 C  CD2    . PHE B 1  130 ? 2.23026   -0.68369  -10.08182 1.000 37.80205  ? 160 PHE B CD2    1 
ATOM   3164 C  CE1    . PHE B 1  130 ? 3.92462   -2.06262  -11.78324 1.000 35.62006  ? 160 PHE B CE1    1 
ATOM   3165 C  CE2    . PHE B 1  130 ? 1.77302   -1.13377  -11.31392 1.000 35.43894  ? 160 PHE B CE2    1 
ATOM   3166 C  CZ     . PHE B 1  130 ? 2.62517   -1.83154  -12.16247 1.000 34.77985  ? 160 PHE B CZ     1 
ATOM   3167 N  N      . ILE B 1  131 ? 4.24845   2.28312   -10.40002 1.000 35.02938  ? 161 ILE B N      1 
ATOM   3168 C  CA     . ILE B 1  131 ? 3.46724   3.12060   -11.30385 1.000 35.49467  ? 161 ILE B CA     1 
ATOM   3169 C  C      . ILE B 1  131 ? 3.24241   2.35282   -12.59244 1.000 30.25951  ? 161 ILE B C      1 
ATOM   3170 O  O      . ILE B 1  131 ? 4.19963   1.85161   -13.19508 1.000 35.73664  ? 161 ILE B O      1 
ATOM   3171 C  CB     . ILE B 1  131 ? 4.15291   4.46247   -11.60564 1.000 36.81447  ? 161 ILE B CB     1 
ATOM   3172 C  CG1    . ILE B 1  131 ? 4.49882   5.21831   -10.31446 1.000 39.98815  ? 161 ILE B CG1    1 
ATOM   3173 C  CG2    . ILE B 1  131 ? 3.24809   5.31859   -12.50915 1.000 36.84627  ? 161 ILE B CG2    1 
ATOM   3174 C  CD1    . ILE B 1  131 ? 3.28961   5.77452   -9.59430  1.000 41.07665  ? 161 ILE B CD1    1 
ATOM   3175 N  N      . ASN B 1  132 ? 1.98361   2.27950   -13.01468 1.000 35.40116  ? 162 ASN B N      1 
ATOM   3176 C  CA     . ASN B 1  132 ? 1.60237   1.70772   -14.31014 1.000 36.64420  ? 162 ASN B CA     1 
ATOM   3177 C  C      . ASN B 1  132 ? 1.44598   2.86589   -15.29375 1.000 38.75750  ? 162 ASN B C      1 
ATOM   3178 O  O      . ASN B 1  132 ? 0.37672   3.46774   -15.40266 1.000 36.23856  ? 162 ASN B O      1 
ATOM   3179 C  CB     . ASN B 1  132 ? 0.31496   0.90325   -14.19923 1.000 36.91373  ? 162 ASN B CB     1 
ATOM   3180 C  CG     . ASN B 1  132 ? 0.00801   0.11974   -15.46852 1.000 34.51851  ? 162 ASN B CG     1 
ATOM   3181 O  OD1    . ASN B 1  132 ? 0.49405   0.44937   -16.55509 1.000 36.80192  ? 162 ASN B OD1    1 
ATOM   3182 N  ND2    . ASN B 1  132 ? -0.80456  -0.91795  -15.33371 1.000 36.15225  ? 162 ASN B ND2    1 
ATOM   3183 N  N      . VAL B 1  133 ? 2.53752   3.18683   -15.99701 1.000 36.49581  ? 163 VAL B N      1 
ATOM   3184 C  CA     . VAL B 1  133 ? 2.53090   4.29950   -16.94202 1.000 38.45551  ? 163 VAL B CA     1 
ATOM   3185 C  C      . VAL B 1  133 ? 1.63534   4.00041   -18.14333 1.000 42.32621  ? 163 VAL B C      1 
ATOM   3186 O  O      . VAL B 1  133 ? 1.05019   4.91713   -18.73598 1.000 39.88645  ? 163 VAL B O      1 
ATOM   3187 C  CB     . VAL B 1  133 ? 3.97398   4.62181   -17.37161 1.000 39.31855  ? 163 VAL B CB     1 
ATOM   3188 C  CG1    . VAL B 1  133 ? 3.98744   5.69151   -18.45494 1.000 48.97077  ? 163 VAL B CG1    1 
ATOM   3189 C  CG2    . VAL B 1  133 ? 4.79376   5.07068   -16.17257 1.000 41.39306  ? 163 VAL B CG2    1 
ATOM   3190 N  N      . ASP B 1  134 ? 1.52807   2.73050   -18.54207 1.000 42.65077  ? 164 ASP B N      1 
ATOM   3191 C  CA     . ASP B 1  134 ? 0.65543   2.37819   -19.65738 1.000 39.52194  ? 164 ASP B CA     1 
ATOM   3192 C  C      . ASP B 1  134 ? -0.79943  2.69660   -19.33526 1.000 41.39448  ? 164 ASP B C      1 
ATOM   3193 O  O      . ASP B 1  134 ? -1.49332  3.36762   -20.11551 1.000 38.62814  ? 164 ASP B O      1 
ATOM   3194 C  CB     . ASP B 1  134 ? 0.83283   0.90065   -20.00064 1.000 38.87820  ? 164 ASP B CB     1 
ATOM   3195 C  CG     . ASP B 1  134 ? 2.28666   0.53867   -20.24829 1.000 56.21998  ? 164 ASP B CG     1 
ATOM   3196 O  OD1    . ASP B 1  134 ? 2.78863   0.78970   -21.36502 1.000 55.25154  ? 164 ASP B OD1    1 
ATOM   3197 O  OD2    . ASP B 1  134 ? 2.94037   0.03098   -19.30889 1.000 67.38242  ? 164 ASP B OD2    1 
ATOM   3198 N  N      . TYR B 1  135 ? -1.27980  2.24102   -18.17301 1.000 32.71039  ? 165 TYR B N      1 
ATOM   3199 C  CA     . TYR B 1  135 ? -2.66467  2.52267   -17.82013 1.000 29.04901  ? 165 TYR B CA     1 
ATOM   3200 C  C      . TYR B 1  135 ? -2.86066  4.00462   -17.52312 1.000 38.51486  ? 165 TYR B C      1 
ATOM   3201 O  O      . TYR B 1  135 ? -3.90533  4.56979   -17.86253 1.000 34.09408  ? 165 TYR B O      1 
ATOM   3202 C  CB     . TYR B 1  135 ? -3.09616  1.66312   -16.63456 1.000 32.29244  ? 165 TYR B CB     1 
ATOM   3203 C  CG     . TYR B 1  135 ? -4.58917  1.60439   -16.37969 1.000 29.48700  ? 165 TYR B CG     1 
ATOM   3204 C  CD1    . TYR B 1  135 ? -5.47208  1.17356   -17.37155 1.000 38.84997  ? 165 TYR B CD1    1 
ATOM   3205 C  CD2    . TYR B 1  135 ? -5.11433  1.93671   -15.14269 1.000 30.20395  ? 165 TYR B CD2    1 
ATOM   3206 C  CE1    . TYR B 1  135 ? -6.83632  1.10927   -17.13850 1.000 34.27481  ? 165 TYR B CE1    1 
ATOM   3207 C  CE2    . TYR B 1  135 ? -6.47615  1.86946   -14.89265 1.000 35.61625  ? 165 TYR B CE2    1 
ATOM   3208 C  CZ     . TYR B 1  135 ? -7.33764  1.45805   -15.89936 1.000 39.16434  ? 165 TYR B CZ     1 
ATOM   3209 O  OH     . TYR B 1  135 ? -8.69264  1.38005   -15.65508 1.000 36.78668  ? 165 TYR B OH     1 
ATOM   3210 N  N      . LEU B 1  136 ? -1.87720  4.64876   -16.87661 1.000 36.96386  ? 166 LEU B N      1 
ATOM   3211 C  CA     . LEU B 1  136 ? -1.99668  6.07996   -16.61613 1.000 34.20315  ? 166 LEU B CA     1 
ATOM   3212 C  C      . LEU B 1  136 ? -2.15246  6.84675   -17.91988 1.000 36.48399  ? 166 LEU B C      1 
ATOM   3213 O  O      . LEU B 1  136 ? -2.98573  7.75077   -18.02418 1.000 35.50313  ? 166 LEU B O      1 
ATOM   3214 C  CB     . LEU B 1  136 ? -0.78477  6.60335   -15.84792 1.000 33.86296  ? 166 LEU B CB     1 
ATOM   3215 C  CG     . LEU B 1  136 ? -0.78922  8.12540   -15.64083 1.000 33.59963  ? 166 LEU B CG     1 
ATOM   3216 C  CD1    . LEU B 1  136 ? -2.06897  8.57273   -14.95346 1.000 32.35549  ? 166 LEU B CD1    1 
ATOM   3217 C  CD2    . LEU B 1  136 ? 0.42718   8.58407   -14.86024 1.000 34.03941  ? 166 LEU B CD2    1 
ATOM   3218 N  N      . THR B 1  137 ? -1.31764  6.52579   -18.91063 1.000 40.33441  ? 167 THR B N      1 
ATOM   3219 C  CA     . THR B 1  137 ? -1.41520  7.16613   -20.22022 1.000 44.38553  ? 167 THR B CA     1 
ATOM   3220 C  C      . THR B 1  137 ? -2.78984  6.94618   -20.83790 1.000 41.96524  ? 167 THR B C      1 
ATOM   3221 O  O      . THR B 1  137 ? -3.41989  7.88699   -21.34341 1.000 40.36035  ? 167 THR B O      1 
ATOM   3222 C  CB     . THR B 1  137 ? -0.32971  6.61663   -21.14839 1.000 39.79889  ? 167 THR B CB     1 
ATOM   3223 O  OG1    . THR B 1  137 ? 0.95405   7.06223   -20.70449 1.000 43.27578  ? 167 THR B OG1    1 
ATOM   3224 C  CG2    . THR B 1  137 ? -0.56404  7.08430   -22.58678 1.000 48.74537  ? 167 THR B CG2    1 
ATOM   3225 N  N      . GLU B 1  138 ? -3.26504  5.69842   -20.82313 1.000 38.31117  ? 168 GLU B N      1 
ATOM   3226 C  CA     . GLU B 1  138 ? -4.58659  5.41228   -21.37067 1.000 38.19990  ? 168 GLU B CA     1 
ATOM   3227 C  C      . GLU B 1  138 ? -5.65999  6.25190   -20.68003 1.000 45.88003  ? 168 GLU B C      1 
ATOM   3228 O  O      . GLU B 1  138 ? -6.53617  6.83584   -21.33745 1.000 36.09473  ? 168 GLU B O      1 
ATOM   3229 C  CB     . GLU B 1  138 ? -4.86642  3.91071   -21.25641 1.000 38.53440  ? 168 GLU B CB     1 
ATOM   3230 C  CG     . GLU B 1  138 ? -6.32340  3.47486   -21.41469 1.000 43.20664  ? 168 GLU B CG     1 
ATOM   3231 C  CD     . GLU B 1  138 ? -6.47731  1.95354   -21.30956 1.000 54.72461  ? 168 GLU B CD     1 
ATOM   3232 O  OE1    . GLU B 1  138 ? -5.45359  1.24239   -21.43064 1.000 58.96115  ? 168 GLU B OE1    1 
ATOM   3233 O  OE2    . GLU B 1  138 ? -7.61232  1.46710   -21.09712 1.000 52.35916  ? 168 GLU B OE2    1 
ATOM   3234 N  N      . LEU B 1  139 ? -5.58407  6.36016   -19.35434 1.000 37.88093  ? 169 LEU B N      1 
ATOM   3235 C  CA     . LEU B 1  139 ? -6.59680  7.10372   -18.61797 1.000 32.56376  ? 169 LEU B CA     1 
ATOM   3236 C  C      . LEU B 1  139 ? -6.48739  8.60254   -18.86929 1.000 31.34174  ? 169 LEU B C      1 
ATOM   3237 O  O      . LEU B 1  139 ? -7.50645  9.28895   -18.92616 1.000 33.27185  ? 169 LEU B O      1 
ATOM   3238 C  CB     . LEU B 1  139 ? -6.49995  6.79839   -17.12119 1.000 36.95205  ? 169 LEU B CB     1 
ATOM   3239 C  CG     . LEU B 1  139 ? -6.90719  5.38114   -16.70517 1.000 38.28996  ? 169 LEU B CG     1 
ATOM   3240 C  CD1    . LEU B 1  139 ? -6.76468  5.18093   -15.19771 1.000 38.94781  ? 169 LEU B CD1    1 
ATOM   3241 C  CD2    . LEU B 1  139 ? -8.33220  5.09010   -17.13771 1.000 36.96613  ? 169 LEU B CD2    1 
ATOM   3242 N  N      . LEU B 1  140 ? -5.27008  9.13107   -18.99139 1.000 31.03707  ? 170 LEU B N      1 
ATOM   3243 C  CA     . LEU B 1  140 ? -5.11338  10.55698  -19.26433 1.000 33.88873  ? 170 LEU B CA     1 
ATOM   3244 C  C      . LEU B 1  140 ? -5.67195  10.90303  -20.63688 1.000 38.54602  ? 170 LEU B C      1 
ATOM   3245 O  O      . LEU B 1  140 ? -6.33526  11.93551  -20.80977 1.000 37.03425  ? 170 LEU B O      1 
ATOM   3246 C  CB     . LEU B 1  140 ? -3.64237  10.96571  -19.16461 1.000 34.57020  ? 170 LEU B CB     1 
ATOM   3247 C  CG     . LEU B 1  140 ? -3.03012  10.94183  -17.75495 1.000 39.51183  ? 170 LEU B CG     1 
ATOM   3248 C  CD1    . LEU B 1  140 ? -1.55045  11.08969  -17.86287 1.000 31.80247  ? 170 LEU B CD1    1 
ATOM   3249 C  CD2    . LEU B 1  140 ? -3.62026  12.06289  -16.89571 1.000 37.08646  ? 170 LEU B CD2    1 
ATOM   3250 N  N      . LEU B 1  141 ? -5.41480  10.04557  -21.62313 1.000 39.22562  ? 171 LEU B N      1 
ATOM   3251 C  CA     . LEU B 1  141 ? -5.96890  10.27232  -22.95200 1.000 38.59740  ? 171 LEU B CA     1 
ATOM   3252 C  C      . LEU B 1  141 ? -7.48986  10.16825  -22.94582 1.000 35.42303  ? 171 LEU B C      1 
ATOM   3253 O  O      . LEU B 1  141 ? -8.16830  10.98063  -23.58898 1.000 41.73469  ? 171 LEU B O      1 
ATOM   3254 C  CB     . LEU B 1  141 ? -5.35501  9.26415   -23.92709 1.000 32.62289  ? 171 LEU B CB     1 
ATOM   3255 C  CG     . LEU B 1  141 ? -3.87909  9.52320   -24.20260 1.000 31.35624  ? 171 LEU B CG     1 
ATOM   3256 C  CD1    . LEU B 1  141 ? -3.24743  8.33187   -24.89385 1.000 47.36577  ? 171 LEU B CD1    1 
ATOM   3257 C  CD2    . LEU B 1  141 ? -3.72737  10.76325  -25.06435 1.000 37.68227  ? 171 LEU B CD2    1 
ATOM   3258 N  N      . LYS B 1  142 ? -8.05400  9.26760   -22.14015 1.000 34.47082  ? 172 LYS B N      1 
ATOM   3259 C  CA     . LYS B 1  142 ? -9.50694  9.15885   -22.12134 1.000 38.47637  ? 172 LYS B CA     1 
ATOM   3260 C  C      . LYS B 1  142 ? -10.14911 10.28061  -21.32075 1.000 42.16099  ? 172 LYS B C      1 
ATOM   3261 O  O      . LYS B 1  142 ? -11.23085 10.75437  -21.69167 1.000 34.73429  ? 172 LYS B O      1 
ATOM   3262 C  CB     . LYS B 1  142 ? -9.92673  7.80785   -21.54618 1.000 41.78667  ? 172 LYS B CB     1 
ATOM   3263 C  CG     . LYS B 1  142 ? -11.43352 7.63794   -21.34461 1.000 50.71443  ? 172 LYS B CG     1 
ATOM   3264 C  CD     . LYS B 1  142 ? -11.72196 6.64266   -20.22360 1.000 62.69956  ? 172 LYS B CD     1 
ATOM   3265 C  CE     . LYS B 1  142 ? -13.21444 6.44231   -20.01189 1.000 71.35194  ? 172 LYS B CE     1 
ATOM   3266 N  NZ     . LYS B 1  142 ? -13.89492 7.69552   -19.57537 1.000 72.45157  ? 172 LYS B NZ     1 
ATOM   3267 N  N      . LYS B 1  143 ? -9.48311  10.75314  -20.26021 1.000 32.18015  ? 173 LYS B N      1 
ATOM   3268 C  CA     . LYS B 1  143 ? -10.05674 11.82064  -19.45625 1.000 33.65747  ? 173 LYS B CA     1 
ATOM   3269 C  C      . LYS B 1  143 ? -10.09503 13.10268  -20.25094 1.000 30.13223  ? 173 LYS B C      1 
ATOM   3270 O  O      . LYS B 1  143 ? -11.03811 13.88819  -20.10928 1.000 33.40840  ? 173 LYS B O      1 
ATOM   3271 C  CB     . LYS B 1  143 ? -9.24359  12.03839  -18.17308 1.000 33.24149  ? 173 LYS B CB     1 
ATOM   3272 C  CG     . LYS B 1  143 ? -9.85915  13.07891  -17.22914 1.000 33.54531  ? 173 LYS B CG     1 
ATOM   3273 C  CD     . LYS B 1  143 ? -11.03507 12.52433  -16.46683 1.000 45.49436  ? 173 LYS B CD     1 
ATOM   3274 C  CE     . LYS B 1  143 ? -11.42971 13.42846  -15.32119 1.000 42.33060  ? 173 LYS B CE     1 
ATOM   3275 N  NZ     . LYS B 1  143 ? -12.81573 13.13320  -14.86824 1.000 51.37569  ? 173 LYS B NZ     1 
ATOM   3276 N  N      . ASN B 1  144 ? -9.09920  13.31250  -21.10596 1.000 29.52074  ? 174 ASN B N      1 
ATOM   3277 C  CA     . ASN B 1  144 ? -9.13292  14.42487  -22.04697 1.000 36.86391  ? 174 ASN B CA     1 
ATOM   3278 C  C      . ASN B 1  144 ? -9.26636  15.76431  -21.33186 1.000 40.58911  ? 174 ASN B C      1 
ATOM   3279 O  O      . ASN B 1  144 ? -10.00166 16.65133  -21.76495 1.000 37.69750  ? 174 ASN B O      1 
ATOM   3280 C  CB     . ASN B 1  144 ? -10.27220 14.21855  -23.03719 1.000 31.79650  ? 174 ASN B CB     1 
ATOM   3281 C  CG     . ASN B 1  144 ? -10.20030 15.15452  -24.22233 1.000 31.03416  ? 174 ASN B CG     1 
ATOM   3282 O  OD1    . ASN B 1  144 ? -9.12371  15.45310  -24.76420 1.000 31.30749  ? 174 ASN B OD1    1 
ATOM   3283 N  ND2    . ASN B 1  144 ? -11.34723 15.60645  -24.63119 1.000 32.08767  ? 174 ASN B ND2    1 
ATOM   3284 N  N      . ARG B 1  145 ? -8.56381  15.90601  -20.21632 1.000 38.13351  ? 175 ARG B N      1 
ATOM   3285 C  CA     . ARG B 1  145 ? -8.51922  17.15089  -19.45697 1.000 39.17871  ? 175 ARG B CA     1 
ATOM   3286 C  C      . ARG B 1  145 ? -7.07588  17.61188  -19.55900 1.000 36.95314  ? 175 ARG B C      1 
ATOM   3287 O  O      . ARG B 1  145 ? -6.20439  17.10298  -18.85493 1.000 36.13671  ? 175 ARG B O      1 
ATOM   3288 C  CB     . ARG B 1  145 ? -8.95953  16.94299  -18.01578 1.000 36.80499  ? 175 ARG B CB     1 
ATOM   3289 C  CG     . ARG B 1  145 ? -10.41433 16.56553  -17.85437 1.000 40.96439  ? 175 ARG B CG     1 
ATOM   3290 C  CD     . ARG B 1  145 ? -11.27121 17.81695  -17.83160 1.000 44.40114  ? 175 ARG B CD     1 
ATOM   3291 N  NE     . ARG B 1  145 ? -10.91656 18.67823  -16.70889 1.000 51.64698  ? 175 ARG B NE     1 
ATOM   3292 C  CZ     . ARG B 1  145 ? -10.07717 19.70677  -16.77381 1.000 49.85384  ? 175 ARG B CZ     1 
ATOM   3293 N  NH1    . ARG B 1  145 ? -9.57151  20.11536  -17.92518 1.000 49.52297  ? 175 ARG B NH1    1 
ATOM   3294 N  NH2    . ARG B 1  145 ? -9.75781  20.36039  -15.65584 1.000 45.63285  ? 175 ARG B NH2    1 
ATOM   3295 N  N      . THR B 1  146 ? -6.83404  18.58258  -20.43704 1.000 33.69056  ? 176 THR B N      1 
ATOM   3296 C  CA     . THR B 1  146 ? -5.48813  19.00341  -20.80318 1.000 40.05582  ? 176 THR B CA     1 
ATOM   3297 C  C      . THR B 1  146 ? -5.04598  20.32056  -20.17038 1.000 35.45115  ? 176 THR B C      1 
ATOM   3298 O  O      . THR B 1  146 ? -3.88570  20.70831  -20.34904 1.000 34.18828  ? 176 THR B O      1 
ATOM   3299 C  CB     . THR B 1  146 ? -5.39175  19.11273  -22.32596 1.000 43.76269  ? 176 THR B CB     1 
ATOM   3300 O  OG1    . THR B 1  146 ? -6.34543  20.07914  -22.78016 1.000 45.82024  ? 176 THR B OG1    1 
ATOM   3301 C  CG2    . THR B 1  146 ? -5.71125  17.76965  -22.95893 1.000 46.40621  ? 176 THR B CG2    1 
ATOM   3302 N  N      . THR B 1  147 ? -5.93339  21.03667  -19.48099 1.000 35.07474  ? 177 THR B N      1 
ATOM   3303 C  CA     . THR B 1  147 ? -5.54787  22.26570  -18.79725 1.000 31.67512  ? 177 THR B CA     1 
ATOM   3304 C  C      . THR B 1  147 ? -6.22201  22.33025  -17.43477 1.000 32.40838  ? 177 THR B C      1 
ATOM   3305 O  O      . THR B 1  147 ? -7.33752  21.82784  -17.25154 1.000 33.24397  ? 177 THR B O      1 
ATOM   3306 C  CB     . THR B 1  147 ? -5.91816  23.53489  -19.60237 1.000 37.60439  ? 177 THR B CB     1 
ATOM   3307 O  OG1    . THR B 1  147 ? -7.33846  23.60579  -19.76431 1.000 40.27031  ? 177 THR B OG1    1 
ATOM   3308 C  CG2    . THR B 1  147 ? -5.26404  23.50906  -20.95813 1.000 36.84726  ? 177 THR B CG2    1 
ATOM   3309 N  N      . ARG B 1  148 ? -5.54303  22.98637  -16.48725 1.000 40.16706  ? 178 ARG B N      1 
ATOM   3310 C  CA     . ARG B 1  148 ? -6.06978  23.18680  -15.13347 1.000 42.74211  ? 178 ARG B CA     1 
ATOM   3311 C  C      . ARG B 1  148 ? -6.61433  21.88380  -14.55898 1.000 34.74559  ? 178 ARG B C      1 
ATOM   3312 O  O      . ARG B 1  148 ? -7.70840  21.83934  -13.98087 1.000 31.50409  ? 178 ARG B O      1 
ATOM   3313 C  CB     . ARG B 1  148 ? -7.13403  24.28514  -15.10751 1.000 38.64849  ? 178 ARG B CB     1 
ATOM   3314 C  CG     . ARG B 1  148 ? -6.56624  25.66784  -15.43694 1.000 42.11220  ? 178 ARG B CG     1 
ATOM   3315 C  CD     . ARG B 1  148 ? -7.63976  26.73588  -15.50639 1.000 44.99053  ? 178 ARG B CD     1 
ATOM   3316 N  NE     . ARG B 1  148 ? -8.46630  26.83433  -14.30955 1.000 41.40134  ? 178 ARG B NE     1 
ATOM   3317 C  CZ     . ARG B 1  148 ? -8.17875  27.58829  -13.25513 1.000 46.34741  ? 178 ARG B CZ     1 
ATOM   3318 N  NH1    . ARG B 1  148 ? -7.01576  28.21465  -13.14379 1.000 40.20287  ? 178 ARG B NH1    1 
ATOM   3319 N  NH2    . ARG B 1  148 ? -9.08004  27.71605  -12.28532 1.000 45.71236  ? 178 ARG B NH2    1 
ATOM   3320 N  N      . PHE B 1  149 ? -5.84662  20.80835  -14.74460 1.000 35.50218  ? 179 PHE B N      1 
ATOM   3321 C  CA     . PHE B 1  149 ? -6.23650  19.46584  -14.32660 1.000 34.82842  ? 179 PHE B CA     1 
ATOM   3322 C  C      . PHE B 1  149 ? -5.30559  18.96323  -13.22890 1.000 32.61394  ? 179 PHE B C      1 
ATOM   3323 O  O      . PHE B 1  149 ? -4.07752  19.03054  -13.36526 1.000 32.32500  ? 179 PHE B O      1 
ATOM   3324 C  CB     . PHE B 1  149 ? -6.22355  18.50152  -15.51733 1.000 31.58815  ? 179 PHE B CB     1 
ATOM   3325 C  CG     . PHE B 1  149 ? -6.57737  17.06935  -15.16798 1.000 32.84331  ? 179 PHE B CG     1 
ATOM   3326 C  CD1    . PHE B 1  149 ? -7.85626  16.73541  -14.75017 1.000 34.03858  ? 179 PHE B CD1    1 
ATOM   3327 C  CD2    . PHE B 1  149 ? -5.64457  16.05836  -15.30694 1.000 34.26643  ? 179 PHE B CD2    1 
ATOM   3328 C  CE1    . PHE B 1  149 ? -8.18799  15.41730  -14.43819 1.000 34.70260  ? 179 PHE B CE1    1 
ATOM   3329 C  CE2    . PHE B 1  149 ? -5.96999  14.73559  -15.00328 1.000 33.16198  ? 179 PHE B CE2    1 
ATOM   3330 C  CZ     . PHE B 1  149 ? -7.24456  14.41967  -14.57435 1.000 29.77002  ? 179 PHE B CZ     1 
ATOM   3331 N  N      . PHE B 1  150 ? -5.89384  18.41537  -12.16912 1.000 29.92338  ? 180 PHE B N      1 
ATOM   3332 C  CA     . PHE B 1  150 ? -5.11953  17.90318  -11.04528 1.000 32.27786  ? 180 PHE B CA     1 
ATOM   3333 C  C      . PHE B 1  150 ? -5.86319  16.71326  -10.46064 1.000 25.48562  ? 180 PHE B C      1 
ATOM   3334 O  O      . PHE B 1  150 ? -7.05495  16.82215  -10.13626 1.000 31.08274  ? 180 PHE B O      1 
ATOM   3335 C  CB     . PHE B 1  150 ? -4.90904  18.99127  -9.98843  1.000 29.88466  ? 180 PHE B CB     1 
ATOM   3336 C  CG     . PHE B 1  150 ? -3.76869  18.70693  -9.04775  1.000 32.19970  ? 180 PHE B CG     1 
ATOM   3337 C  CD1    . PHE B 1  150 ? -3.93762  17.82471  -7.97724  1.000 36.85087  ? 180 PHE B CD1    1 
ATOM   3338 C  CD2    . PHE B 1  150 ? -2.52395  19.27844  -9.24727  1.000 32.95470  ? 180 PHE B CD2    1 
ATOM   3339 C  CE1    . PHE B 1  150 ? -2.87700  17.54225  -7.10540  1.000 28.82077  ? 180 PHE B CE1    1 
ATOM   3340 C  CE2    . PHE B 1  150 ? -1.46291  19.00166  -8.38395  1.000 38.52010  ? 180 PHE B CE2    1 
ATOM   3341 C  CZ     . PHE B 1  150 ? -1.63823  18.12846  -7.31544  1.000 30.39966  ? 180 PHE B CZ     1 
ATOM   3342 N  N      . THR B 1  151 ? -5.17502  15.57773  -10.34429 1.000 28.56093  ? 181 THR B N      1 
ATOM   3343 C  CA     . THR B 1  151 ? -5.81716  14.36475  -9.87227  1.000 28.10149  ? 181 THR B CA     1 
ATOM   3344 C  C      . THR B 1  151 ? -4.83368  13.53271  -9.05572  1.000 29.59565  ? 181 THR B C      1 
ATOM   3345 O  O      . THR B 1  151 ? -3.62291  13.77822  -9.03972  1.000 27.23315  ? 181 THR B O      1 
ATOM   3346 C  CB     . THR B 1  151 ? -6.34882  13.51753  -11.03352 1.000 32.72544  ? 181 THR B CB     1 
ATOM   3347 O  OG1    . THR B 1  151 ? -7.22327  12.49953  -10.52447 1.000 32.38605  ? 181 THR B OG1    1 
ATOM   3348 C  CG2    . THR B 1  151 ? -5.19138  12.84751  -11.72909 1.000 27.60295  ? 181 THR B CG2    1 
ATOM   3349 N  N      . GLY B 1  152 ? -5.37461  12.49213  -8.44551  1.000 31.58711  ? 182 GLY B N      1 
ATOM   3350 C  CA     . GLY B 1  152 ? -4.60504  11.56054  -7.63011  1.000 31.72930  ? 182 GLY B CA     1 
ATOM   3351 C  C      . GLY B 1  152 ? -5.53798  10.85773  -6.66536  1.000 31.49672  ? 182 GLY B C      1 
ATOM   3352 O  O      . GLY B 1  152 ? -6.69318  10.58068  -6.99468  1.000 31.50403  ? 182 GLY B O      1 
ATOM   3353 N  N      . PHE B 1  153 ? -5.02108  10.58573  -5.46532  1.000 32.76984  ? 183 PHE B N      1 
ATOM   3354 C  CA     . PHE B 1  153 ? -5.86776  10.13153  -4.36899  1.000 27.83912  ? 183 PHE B CA     1 
ATOM   3355 C  C      . PHE B 1  153 ? -6.38101  11.37074  -3.64039  1.000 35.33984  ? 183 PHE B C      1 
ATOM   3356 O  O      . PHE B 1  153 ? -5.63406  12.02278  -2.90480  1.000 30.41389  ? 183 PHE B O      1 
ATOM   3357 C  CB     . PHE B 1  153 ? -5.10642  9.20057   -3.42450  1.000 34.65804  ? 183 PHE B CB     1 
ATOM   3358 C  CG     . PHE B 1  153 ? -5.95285  8.67134   -2.30473  1.000 37.22730  ? 183 PHE B CG     1 
ATOM   3359 C  CD1    . PHE B 1  153 ? -6.76937  7.56720   -2.49989  1.000 35.31381  ? 183 PHE B CD1    1 
ATOM   3360 C  CD2    . PHE B 1  153 ? -5.95597  9.29080   -1.06701  1.000 35.22023  ? 183 PHE B CD2    1 
ATOM   3361 C  CE1    . PHE B 1  153 ? -7.56058  7.08383   -1.47208  1.000 43.13643  ? 183 PHE B CE1    1 
ATOM   3362 C  CE2    . PHE B 1  153 ? -6.74488  8.81687   -0.04072  1.000 37.16637  ? 183 PHE B CE2    1 
ATOM   3363 C  CZ     . PHE B 1  153 ? -7.54762  7.70932   -0.23791  1.000 41.90940  ? 183 PHE B CZ     1 
ATOM   3364 N  N      . LEU B 1  154 ? -7.65609  11.69072  -3.83502  1.000 34.97952  ? 184 LEU B N      1 
ATOM   3365 C  CA     . LEU B 1  154 ? -8.21628  12.91498  -3.28570  1.000 38.15719  ? 184 LEU B CA     1 
ATOM   3366 C  C      . LEU B 1  154 ? -8.44290  12.78322  -1.78363  1.000 35.97947  ? 184 LEU B C      1 
ATOM   3367 O  O      . LEU B 1  154 ? -9.01144  11.79114  -1.31002  1.000 37.46980  ? 184 LEU B O      1 
ATOM   3368 C  CB     . LEU B 1  154 ? -9.52136  13.26252  -4.00372  1.000 39.81673  ? 184 LEU B CB     1 
ATOM   3369 C  CG     . LEU B 1  154 ? -9.33616  13.97486  -5.35112  1.000 38.23045  ? 184 LEU B CG     1 
ATOM   3370 C  CD1    . LEU B 1  154 ? -8.60367  13.09079  -6.35411  1.000 34.13214  ? 184 LEU B CD1    1 
ATOM   3371 C  CD2    . LEU B 1  154 ? -10.68138 14.44120  -5.91763  1.000 38.96519  ? 184 LEU B CD2    1 
ATOM   3372 N  N      . LYS B 1  155 ? -8.01601  13.80595  -1.04465  1.000 33.10305  ? 185 LYS B N      1 
ATOM   3373 C  CA     . LYS B 1  155 ? -8.15832  13.90009  0.40717   1.000 38.98789  ? 185 LYS B CA     1 
ATOM   3374 C  C      . LYS B 1  155 ? -8.92008  15.19339  0.67711   1.000 35.03486  ? 185 LYS B C      1 
ATOM   3375 O  O      . LYS B 1  155 ? -8.32680  16.27566  0.70759   1.000 32.35681  ? 185 LYS B O      1 
ATOM   3376 C  CB     . LYS B 1  155 ? -6.79122  13.88600  1.09130   1.000 31.29526  ? 185 LYS B CB     1 
ATOM   3377 C  CG     . LYS B 1  155 ? -5.99266  12.63876  0.79925   1.000 28.83896  ? 185 LYS B CG     1 
ATOM   3378 C  CD     . LYS B 1  155 ? -4.54642  12.75341  1.23808   1.000 37.09048  ? 185 LYS B CD     1 
ATOM   3379 C  CE     . LYS B 1  155 ? -4.41101  12.71673  2.75808   1.000 36.21977  ? 185 LYS B CE     1 
ATOM   3380 N  NZ     . LYS B 1  155 ? -5.00280  11.49531  3.36334   1.000 33.96030  ? 185 LYS B NZ     1 
ATOM   3381 N  N      . LEU B 1  156 ? -10.23520 15.07786  0.87594   1.000 34.75438  ? 186 LEU B N      1 
ATOM   3382 C  CA     . LEU B 1  156 ? -11.12730 16.22926  0.84625   1.000 39.58949  ? 186 LEU B CA     1 
ATOM   3383 C  C      . LEU B 1  156 ? -11.57031 16.71580  2.21773   1.000 44.55163  ? 186 LEU B C      1 
ATOM   3384 O  O      . LEU B 1  156 ? -12.05158 17.84630  2.32351   1.000 51.41524  ? 186 LEU B O      1 
ATOM   3385 C  CB     . LEU B 1  156 ? -12.37391 15.90723  0.01996   1.000 36.05922  ? 186 LEU B CB     1 
ATOM   3386 C  CG     . LEU B 1  156 ? -12.04938 15.46517  -1.40868  1.000 40.80817  ? 186 LEU B CG     1 
ATOM   3387 C  CD1    . LEU B 1  156 ? -13.31549 15.15631  -2.22455  1.000 46.36875  ? 186 LEU B CD1    1 
ATOM   3388 C  CD2    . LEU B 1  156 ? -11.18434 16.51068  -2.09876  1.000 32.97652  ? 186 LEU B CD2    1 
ATOM   3389 N  N      . ASN B 1  157 ? -11.44399 15.90868  3.26752   1.000 47.15572  ? 187 ASN B N      1 
ATOM   3390 C  CA     . ASN B 1  157 ? -11.87501 16.34186  4.59233   1.000 56.43490  ? 187 ASN B CA     1 
ATOM   3391 C  C      . ASN B 1  157 ? -10.75373 16.07633  5.60287   1.000 45.71546  ? 187 ASN B C      1 
ATOM   3392 O  O      . ASN B 1  157 ? -10.89278 15.30032  6.54713   1.000 53.32947  ? 187 ASN B O      1 
ATOM   3393 C  CB     . ASN B 1  157 ? -13.18496 15.64769  4.96504   1.000 60.50223  ? 187 ASN B CB     1 
ATOM   3394 C  CG     . ASN B 1  157 ? -13.88457 16.31422  6.12772   1.000 63.79270  ? 187 ASN B CG     1 
ATOM   3395 O  OD1    . ASN B 1  157 ? -14.27761 17.47903  6.03922   1.000 75.25442  ? 187 ASN B OD1    1 
ATOM   3396 N  ND2    . ASN B 1  157 ? -14.06800 15.57595  7.21520   1.000 63.91380  ? 187 ASN B ND2    1 
ATOM   3397 N  N      . GLU B 1  158 ? -9.61930  16.73210  5.38753   1.000 34.31751  ? 188 GLU B N      1 
ATOM   3398 C  CA     . GLU B 1  158 ? -8.42248  16.49831  6.18134   1.000 37.28842  ? 188 GLU B CA     1 
ATOM   3399 C  C      . GLU B 1  158 ? -8.26173  17.56936  7.25449   1.000 42.20341  ? 188 GLU B C      1 
ATOM   3400 O  O      . GLU B 1  158 ? -8.55155  18.74788  7.02574   1.000 36.80241  ? 188 GLU B O      1 
ATOM   3401 C  CB     . GLU B 1  158 ? -7.18059  16.45639  5.29339   1.000 33.44735  ? 188 GLU B CB     1 
ATOM   3402 C  CG     . GLU B 1  158 ? -7.12934  15.23712  4.39473   1.000 40.30724  ? 188 GLU B CG     1 
ATOM   3403 C  CD     . GLU B 1  158 ? -6.97827  13.94232  5.18944   1.000 43.39323  ? 188 GLU B CD     1 
ATOM   3404 O  OE1    . GLU B 1  158 ? -6.22398  13.91900  6.19172   1.000 39.56319  ? 188 GLU B OE1    1 
ATOM   3405 O  OE2    . GLU B 1  158 ? -7.61552  12.94729  4.80159   1.000 45.03086  ? 188 GLU B OE2    1 
ATOM   3406 N  N      . PHE B 1  159 ? -7.82154  17.14269  8.43809   1.000 35.11114  ? 189 PHE B N      1 
ATOM   3407 C  CA     . PHE B 1  159 ? -7.56380  18.03666  9.55270   1.000 36.30266  ? 189 PHE B CA     1 
ATOM   3408 C  C      . PHE B 1  159 ? -6.09414  17.98103  9.94690   1.000 34.25221  ? 189 PHE B C      1 
ATOM   3409 O  O      . PHE B 1  159 ? -5.49475  16.89898  9.94799   1.000 35.64061  ? 189 PHE B O      1 
ATOM   3410 C  CB     . PHE B 1  159 ? -8.44148  17.66817  10.75201  1.000 39.29697  ? 189 PHE B CB     1 
ATOM   3411 C  CG     . PHE B 1  159 ? -9.89689  17.61161  10.41827  1.000 45.65787  ? 189 PHE B CG     1 
ATOM   3412 C  CD1    . PHE B 1  159 ? -10.65964 18.76677  10.38613  1.000 46.98543  ? 189 PHE B CD1    1 
ATOM   3413 C  CD2    . PHE B 1  159 ? -10.50459 16.40095  10.12421  1.000 47.57935  ? 189 PHE B CD2    1 
ATOM   3414 C  CE1    . PHE B 1  159 ? -12.00478 18.71867  10.06436  1.000 56.12662  ? 189 PHE B CE1    1 
ATOM   3415 C  CE2    . PHE B 1  159 ? -11.85170 16.34341  9.80771   1.000 52.87911  ? 189 PHE B CE2    1 
ATOM   3416 C  CZ     . PHE B 1  159 ? -12.60303 17.50483  9.77768   1.000 56.38745  ? 189 PHE B CZ     1 
ATOM   3417 N  N      . PRO B 1  160 ? -5.48126  19.11773  10.26663  1.000 33.09170  ? 190 PRO B N      1 
ATOM   3418 C  CA     . PRO B 1  160 ? -4.07048  19.09502  10.67248  1.000 32.23333  ? 190 PRO B CA     1 
ATOM   3419 C  C      . PRO B 1  160 ? -3.85148  18.18653  11.87876  1.000 32.51864  ? 190 PRO B C      1 
ATOM   3420 O  O      . PRO B 1  160 ? -4.66357  18.14262  12.80574  1.000 33.77386  ? 190 PRO B O      1 
ATOM   3421 C  CB     . PRO B 1  160 ? -3.77001  20.56328  11.00151  1.000 32.73003  ? 190 PRO B CB     1 
ATOM   3422 C  CG     . PRO B 1  160 ? -5.12828  21.22129  11.16272  1.000 35.00198  ? 190 PRO B CG     1 
ATOM   3423 C  CD     . PRO B 1  160 ? -6.04323  20.47912  10.25196  1.000 32.19475  ? 190 PRO B CD     1 
ATOM   3424 N  N      . ILE B 1  161 ? -2.73956  17.46279  11.85815  1.000 28.12062  ? 191 ILE B N      1 
ATOM   3425 C  CA     . ILE B 1  161 ? -2.40160  16.52444  12.93070  1.000 33.69206  ? 191 ILE B CA     1 
ATOM   3426 C  C      . ILE B 1  161 ? -1.63431  17.28668  14.00237  1.000 31.11121  ? 191 ILE B C      1 
ATOM   3427 O  O      . ILE B 1  161 ? -0.55961  17.82866  13.73110  1.000 32.33885  ? 191 ILE B O      1 
ATOM   3428 C  CB     . ILE B 1  161 ? -1.57741  15.34000  12.40672  1.000 38.25136  ? 191 ILE B CB     1 
ATOM   3429 C  CG1    . ILE B 1  161 ? -2.43613  14.44856  11.50682  1.000 35.04133  ? 191 ILE B CG1    1 
ATOM   3430 C  CG2    . ILE B 1  161 ? -0.94675  14.54348  13.58143  1.000 34.91198  ? 191 ILE B CG2    1 
ATOM   3431 C  CD1    . ILE B 1  161 ? -1.62625  13.45415  10.71985  1.000 38.86729  ? 191 ILE B CD1    1 
ATOM   3432 N  N      . ARG B 1  162 ? -2.16844  17.29770  15.22393  1.000 39.42662  ? 192 ARG B N      1 
ATOM   3433 C  CA     . ARG B 1  162 ? -1.59374  18.05317  16.32816  1.000 35.28067  ? 192 ARG B CA     1 
ATOM   3434 C  C      . ARG B 1  162 ? -0.87458  17.17709  17.35233  1.000 38.69463  ? 192 ARG B C      1 
ATOM   3435 O  O      . ARG B 1  162 ? -0.47039  17.68692  18.39935  1.000 39.06910  ? 192 ARG B O      1 
ATOM   3436 C  CB     . ARG B 1  162 ? -2.69254  18.85797  17.02847  1.000 37.95899  ? 192 ARG B CB     1 
ATOM   3437 C  CG     . ARG B 1  162 ? -3.55990  19.68407  16.08859  1.000 38.86247  ? 192 ARG B CG     1 
ATOM   3438 C  CD     . ARG B 1  162 ? -2.76350  20.75625  15.37681  1.000 32.86334  ? 192 ARG B CD     1 
ATOM   3439 N  NE     . ARG B 1  162 ? -3.64846  21.76000  14.79130  1.000 36.08846  ? 192 ARG B NE     1 
ATOM   3440 C  CZ     . ARG B 1  162 ? -3.24271  22.77034  14.03789  1.000 34.02506  ? 192 ARG B CZ     1 
ATOM   3441 N  NH1    . ARG B 1  162 ? -1.96534  22.94710  13.75202  1.000 31.35087  ? 192 ARG B NH1    1 
ATOM   3442 N  NH2    . ARG B 1  162 ? -4.14470  23.62021  13.55524  1.000 36.71900  ? 192 ARG B NH2    1 
ATOM   3443 N  N      . GLN B 1  163 ? -0.70600  15.88026  17.08221  1.000 39.47498  ? 193 GLN B N      1 
ATOM   3444 C  CA     . GLN B 1  163 ? 0.04611   14.97774  17.95205  1.000 36.61474  ? 193 GLN B CA     1 
ATOM   3445 C  C      . GLN B 1  163 ? 1.54527   15.18369  17.77122  1.000 39.51030  ? 193 GLN B C      1 
ATOM   3446 O  O      . GLN B 1  163 ? 2.08411   14.85013  16.70972  1.000 36.38347  ? 193 GLN B O      1 
ATOM   3447 C  CB     . GLN B 1  163 ? -0.31616  13.51748  17.64570  1.000 43.47148  ? 193 GLN B CB     1 
ATOM   3448 C  CG     . GLN B 1  163 ? -1.80737  13.17767  17.73469  1.000 49.49577  ? 193 GLN B CG     1 
ATOM   3449 C  CD     . GLN B 1  163 ? -2.15852  11.85000  17.05408  1.000 66.95180  ? 193 GLN B CD     1 
ATOM   3450 O  OE1    . GLN B 1  163 ? -2.35080  10.82453  17.71572  1.000 63.21850  ? 193 GLN B OE1    1 
ATOM   3451 N  NE2    . GLN B 1  163 ? -2.24985  11.87154  15.72365  1.000 57.02185  ? 193 GLN B NE2    1 
ATOM   3452 N  N      . PRO B 1  164 ? 2.26143   15.71967  18.76752  1.000 44.66643  ? 194 PRO B N      1 
ATOM   3453 C  CA     . PRO B 1  164 ? 3.67178   16.08439  18.54366  1.000 35.52010  ? 194 PRO B CA     1 
ATOM   3454 C  C      . PRO B 1  164 ? 4.58091   14.91389  18.19082  1.000 32.78229  ? 194 PRO B C      1 
ATOM   3455 O  O      . PRO B 1  164 ? 5.70099   15.14562  17.71958  1.000 34.94741  ? 194 PRO B O      1 
ATOM   3456 C  CB     . PRO B 1  164 ? 4.07592   16.76868  19.86255  1.000 43.86866  ? 194 PRO B CB     1 
ATOM   3457 C  CG     . PRO B 1  164 ? 3.04333   16.36983  20.84647  1.000 45.27000  ? 194 PRO B CG     1 
ATOM   3458 C  CD     . PRO B 1  164 ? 1.77253   16.24418  20.05296  1.000 42.47269  ? 194 PRO B CD     1 
ATOM   3459 N  N      . PHE B 1  165 ? 4.14457   13.67120  18.36274  1.000 34.31151  ? 195 PHE B N      1 
ATOM   3460 C  CA     . PHE B 1  165 ? 4.98012   12.54321  17.99052  1.000 36.18227  ? 195 PHE B CA     1 
ATOM   3461 C  C      . PHE B 1  165 ? 4.76593   12.10169  16.54797  1.000 38.15937  ? 195 PHE B C      1 
ATOM   3462 O  O      . PHE B 1  165 ? 5.51715   11.25133  16.05624  1.000 35.80237  ? 195 PHE B O      1 
ATOM   3463 C  CB     . PHE B 1  165 ? 4.65177   11.35805  18.90227  1.000 38.64545  ? 195 PHE B CB     1 
ATOM   3464 C  CG     . PHE B 1  165 ? 3.19339   10.98512  18.87635  1.000 42.45157  ? 195 PHE B CG     1 
ATOM   3465 C  CD1    . PHE B 1  165 ? 2.68157   10.21705  17.84076  1.000 45.65735  ? 195 PHE B CD1    1 
ATOM   3466 C  CD2    . PHE B 1  165 ? 2.32435   11.44284  19.85935  1.000 43.95059  ? 195 PHE B CD2    1 
ATOM   3467 C  CE1    . PHE B 1  165 ? 1.33465   9.89241   17.79443  1.000 47.56466  ? 195 PHE B CE1    1 
ATOM   3468 C  CE2    . PHE B 1  165 ? 0.97647   11.11371  19.82169  1.000 51.15761  ? 195 PHE B CE2    1 
ATOM   3469 C  CZ     . PHE B 1  165 ? 0.48284   10.32886  18.78451  1.000 41.34084  ? 195 PHE B CZ     1 
ATOM   3470 N  N      . SER B 1  166 ? 3.80558   12.69070  15.84064  1.000 37.63539  ? 196 SER B N      1 
ATOM   3471 C  CA     . SER B 1  166 ? 3.54972   12.30697  14.45712  1.000 37.01909  ? 196 SER B CA     1 
ATOM   3472 C  C      . SER B 1  166 ? 4.54289   12.96456  13.50628  1.000 40.46549  ? 196 SER B C      1 
ATOM   3473 O  O      . SER B 1  166 ? 4.91121   14.13312  13.67817  1.000 35.97393  ? 196 SER B O      1 
ATOM   3474 C  CB     . SER B 1  166 ? 2.11877   12.68486  14.06087  1.000 36.72988  ? 196 SER B CB     1 
ATOM   3475 O  OG     . SER B 1  166 ? 1.96475   12.66019  12.65036  1.000 40.29044  ? 196 SER B OG     1 
ATOM   3476 N  N      . LYS B 1  167 ? 4.97491   12.21465  12.48440  1.000 36.66014  ? 197 LYS B N      1 
ATOM   3477 C  CA     . LYS B 1  167 ? 5.84182   12.82249  11.47813  1.000 44.58444  ? 197 LYS B CA     1 
ATOM   3478 C  C      . LYS B 1  167 ? 5.12961   13.96644  10.76954  1.000 37.07640  ? 197 LYS B C      1 
ATOM   3479 O  O      . LYS B 1  167 ? 5.78613   14.83520  10.18973  1.000 40.04579  ? 197 LYS B O      1 
ATOM   3480 C  CB     . LYS B 1  167 ? 6.35595   11.78311  10.46868  1.000 46.21994  ? 197 LYS B CB     1 
ATOM   3481 C  CG     . LYS B 1  167 ? 5.38142   11.35147  9.39134   1.000 46.59456  ? 197 LYS B CG     1 
ATOM   3482 C  CD     . LYS B 1  167 ? 6.02845   10.32629  8.44579   1.000 46.72253  ? 197 LYS B CD     1 
ATOM   3483 C  CE     . LYS B 1  167 ? 7.42600   10.77049  8.01347   1.000 54.23906  ? 197 LYS B CE     1 
ATOM   3484 N  NZ     . LYS B 1  167 ? 8.07653   9.81334   7.06270   1.000 65.20557  ? 197 LYS B NZ     1 
ATOM   3485 N  N      . TRP B 1  168 ? 3.79933   13.97221  10.79397  1.000 36.30887  ? 198 TRP B N      1 
ATOM   3486 C  CA     . TRP B 1  168 ? 2.99971   14.99494  10.13926  1.000 35.61950  ? 198 TRP B CA     1 
ATOM   3487 C  C      . TRP B 1  168 ? 2.43587   16.01353  11.12521  1.000 32.97655  ? 198 TRP B C      1 
ATOM   3488 O  O      . TRP B 1  168 ? 1.46685   16.71167  10.80539  1.000 32.88662  ? 198 TRP B O      1 
ATOM   3489 C  CB     . TRP B 1  168 ? 1.87605   14.33160  9.34444   1.000 41.17793  ? 198 TRP B CB     1 
ATOM   3490 C  CG     . TRP B 1  168 ? 2.40783   13.41141  8.30471   1.000 39.10879  ? 198 TRP B CG     1 
ATOM   3491 C  CD1    . TRP B 1  168 ? 3.44447   13.65607  7.44845   1.000 41.07701  ? 198 TRP B CD1    1 
ATOM   3492 C  CD2    . TRP B 1  168 ? 1.93635   12.09909  8.00053   1.000 41.25171  ? 198 TRP B CD2    1 
ATOM   3493 N  NE1    . TRP B 1  168 ? 3.64672   12.57422  6.62978   1.000 41.55662  ? 198 TRP B NE1    1 
ATOM   3494 C  CE2    . TRP B 1  168 ? 2.73739   11.60139  6.95137   1.000 39.89888  ? 198 TRP B CE2    1 
ATOM   3495 C  CE3    . TRP B 1  168 ? 0.92044   11.29139  8.51536   1.000 47.78353  ? 198 TRP B CE3    1 
ATOM   3496 C  CZ2    . TRP B 1  168 ? 2.54773   10.33687  6.40346   1.000 45.27181  ? 198 TRP B CZ2    1 
ATOM   3497 C  CZ3    . TRP B 1  168 ? 0.73424   10.03348  7.96883   1.000 49.54390  ? 198 TRP B CZ3    1 
ATOM   3498 C  CH2    . TRP B 1  168 ? 1.53984   9.57189   6.92098   1.000 52.69431  ? 198 TRP B CH2    1 
ATOM   3499 N  N      . PHE B 1  169 ? 3.02423   16.10560  12.31868  1.000 33.43332  ? 199 PHE B N      1 
ATOM   3500 C  CA     . PHE B 1  169 ? 2.62276   17.11171  13.29255  1.000 31.97724  ? 199 PHE B CA     1 
ATOM   3501 C  C      . PHE B 1  169 ? 2.87603   18.51346  12.75010  1.000 25.66776  ? 199 PHE B C      1 
ATOM   3502 O  O      . PHE B 1  169 ? 3.94706   18.78206  12.20826  1.000 28.25665  ? 199 PHE B O      1 
ATOM   3503 C  CB     . PHE B 1  169 ? 3.41331   16.91362  14.58907  1.000 37.08923  ? 199 PHE B CB     1 
ATOM   3504 C  CG     . PHE B 1  169 ? 3.35921   18.09768  15.51825  1.000 34.39831  ? 199 PHE B CG     1 
ATOM   3505 C  CD1    . PHE B 1  169 ? 2.20523   18.38945  16.22047  1.000 32.43190  ? 199 PHE B CD1    1 
ATOM   3506 C  CD2    . PHE B 1  169 ? 4.45982   18.92074  15.67277  1.000 35.32118  ? 199 PHE B CD2    1 
ATOM   3507 C  CE1    . PHE B 1  169 ? 2.15397   19.47356  17.06929  1.000 34.36479  ? 199 PHE B CE1    1 
ATOM   3508 C  CE2    . PHE B 1  169 ? 4.41335   20.01065  16.52684  1.000 36.15101  ? 199 PHE B CE2    1 
ATOM   3509 C  CZ     . PHE B 1  169 ? 3.25846   20.28320  17.22752  1.000 32.25567  ? 199 PHE B CZ     1 
ATOM   3510 N  N      . VAL B 1  170 ? 1.89588   19.40891  12.90834  1.000 28.40648  ? 200 VAL B N      1 
ATOM   3511 C  CA     . VAL B 1  170 ? 2.08937   20.83583  12.64348  1.000 33.24491  ? 200 VAL B CA     1 
ATOM   3512 C  C      . VAL B 1  170 ? 1.55250   21.64866  13.81632  1.000 28.75001  ? 200 VAL B C      1 
ATOM   3513 O  O      . VAL B 1  170 ? 0.40236   21.46588  14.23317  1.000 37.26605  ? 200 VAL B O      1 
ATOM   3514 C  CB     . VAL B 1  170 ? 1.41984   21.28679  11.32808  1.000 30.64324  ? 200 VAL B CB     1 
ATOM   3515 C  CG1    . VAL B 1  170 ? 2.09693   20.64993  10.13958  1.000 34.94093  ? 200 VAL B CG1    1 
ATOM   3516 C  CG2    . VAL B 1  170 ? -0.06517  20.94330  11.34646  1.000 34.73678  ? 200 VAL B CG2    1 
ATOM   3517 N  N      . SER B 1  171 ? 2.37097   22.56555  14.32930  1.000 35.80260  ? 201 SER B N      1 
ATOM   3518 C  CA     . SER B 1  171 ? 1.91669   23.44856  15.39639  1.000 41.39660  ? 201 SER B CA     1 
ATOM   3519 C  C      . SER B 1  171 ? 0.84060   24.40321  14.87873  1.000 44.52719  ? 201 SER B C      1 
ATOM   3520 O  O      . SER B 1  171 ? 0.63459   24.55463  13.67079  1.000 39.01285  ? 201 SER B O      1 
ATOM   3521 C  CB     . SER B 1  171 ? 3.08016   24.26152  15.95806  1.000 37.41117  ? 201 SER B CB     1 
ATOM   3522 O  OG     . SER B 1  171 ? 3.40211   25.33059  15.07842  1.000 41.55395  ? 201 SER B OG     1 
ATOM   3523 N  N      . LYS B 1  172 ? 0.14855   25.06597  15.81342  1.000 39.20986  ? 202 LYS B N      1 
ATOM   3524 C  CA     . LYS B 1  172 ? -0.85385  26.04180  15.40420  1.000 41.49337  ? 202 LYS B CA     1 
ATOM   3525 C  C      . LYS B 1  172 ? -0.22242  27.26907  14.76655  1.000 43.76895  ? 202 LYS B C      1 
ATOM   3526 O  O      . LYS B 1  172 ? -0.88225  27.95208  13.97535  1.000 44.07880  ? 202 LYS B O      1 
ATOM   3527 C  CB     . LYS B 1  172 ? -1.73120  26.44839  16.58473  1.000 43.51341  ? 202 LYS B CB     1 
ATOM   3528 C  CG     . LYS B 1  172 ? -2.56248  25.30647  17.12658  1.000 50.14494  ? 202 LYS B CG     1 
ATOM   3529 C  CD     . LYS B 1  172 ? -4.01601  25.69687  17.34020  1.000 51.43249  ? 202 LYS B CD     1 
ATOM   3530 C  CE     . LYS B 1  172 ? -4.77994  24.58467  18.05753  1.000 55.11278  ? 202 LYS B CE     1 
ATOM   3531 N  NZ     . LYS B 1  172 ? -6.10959  25.05418  18.54673  1.000 71.21933  ? 202 LYS B NZ     1 
ATOM   3532 N  N      . SER B 1  173 ? 1.04101   27.55271  15.07021  1.000 41.20310  ? 203 SER B N      1 
ATOM   3533 C  CA     . SER B 1  173 ? 1.72229   28.62384  14.36074  1.000 47.98748  ? 203 SER B CA     1 
ATOM   3534 C  C      . SER B 1  173 ? 2.22001   28.15918  12.99527  1.000 45.00604  ? 203 SER B C      1 
ATOM   3535 O  O      . SER B 1  173 ? 2.36618   28.98246  12.08432  1.000 41.25016  ? 203 SER B O      1 
ATOM   3536 C  CB     . SER B 1  173 ? 2.87155   29.17268  15.21126  1.000 47.29650  ? 203 SER B CB     1 
ATOM   3537 O  OG     . SER B 1  173 ? 4.10379   28.55902  14.88539  1.000 50.54528  ? 203 SER B OG     1 
ATOM   3538 N  N      . GLU B 1  174 ? 2.47204   26.85353  12.82791  1.000 40.20682  ? 204 GLU B N      1 
ATOM   3539 C  CA     . GLU B 1  174 ? 2.80628   26.32796  11.50540  1.000 42.93487  ? 204 GLU B CA     1 
ATOM   3540 C  C      . GLU B 1  174 ? 1.57766   26.28704  10.59991  1.000 39.52000  ? 204 GLU B C      1 
ATOM   3541 O  O      . GLU B 1  174 ? 1.66419   26.61571  9.41028   1.000 38.96528  ? 204 GLU B O      1 
ATOM   3542 C  CB     . GLU B 1  174 ? 3.43569   24.93533  11.62356  1.000 38.07399  ? 204 GLU B CB     1 
ATOM   3543 C  CG     . GLU B 1  174 ? 4.86515   24.93549  12.13741  1.000 37.77662  ? 204 GLU B CG     1 
ATOM   3544 C  CD     . GLU B 1  174 ? 5.39488   23.53494  12.42236  1.000 44.20244  ? 204 GLU B CD     1 
ATOM   3545 O  OE1    . GLU B 1  174 ? 4.63794   22.71233  12.98085  1.000 39.06866  ? 204 GLU B OE1    1 
ATOM   3546 O  OE2    . GLU B 1  174 ? 6.56487   23.25279  12.07662  1.000 49.21852  ? 204 GLU B OE2    1 
ATOM   3547 N  N      . TYR B 1  175 ? 0.43187   25.87885  11.13684  1.000 36.91954  ? 205 TYR B N      1 
ATOM   3548 C  CA     . TYR B 1  175 ? -0.82937  25.92529  10.40288  1.000 35.95682  ? 205 TYR B CA     1 
ATOM   3549 C  C      . TYR B 1  175 ? -1.94620  26.24001  11.38797  1.000 37.53852  ? 205 TYR B C      1 
ATOM   3550 O  O      . TYR B 1  175 ? -2.34710  25.37187  12.17753  1.000 36.42220  ? 205 TYR B O      1 
ATOM   3551 C  CB     . TYR B 1  175 ? -1.11559  24.60605  9.65605   1.000 36.24542  ? 205 TYR B CB     1 
ATOM   3552 C  CG     . TYR B 1  175 ? -2.32988  24.69764  8.75487   1.000 37.46189  ? 205 TYR B CG     1 
ATOM   3553 C  CD1    . TYR B 1  175 ? -2.23444  25.24464  7.47936   1.000 33.87118  ? 205 TYR B CD1    1 
ATOM   3554 C  CD2    . TYR B 1  175 ? -3.57715  24.26735  9.18654   1.000 34.90930  ? 205 TYR B CD2    1 
ATOM   3555 C  CE1    . TYR B 1  175 ? -3.34285  25.34648  6.65474   1.000 31.42533  ? 205 TYR B CE1    1 
ATOM   3556 C  CE2    . TYR B 1  175 ? -4.69328  24.36953  8.37072   1.000 35.84407  ? 205 TYR B CE2    1 
ATOM   3557 C  CZ     . TYR B 1  175 ? -4.56745  24.91514  7.09701   1.000 35.49129  ? 205 TYR B CZ     1 
ATOM   3558 O  OH     . TYR B 1  175 ? -5.66670  25.02480  6.26815   1.000 34.55521  ? 205 TYR B OH     1 
ATOM   3559 N  N      . PRO B 1  176 ? -2.47718  27.46172  11.37532  1.000 35.64164  ? 206 PRO B N      1 
ATOM   3560 C  CA     . PRO B 1  176 ? -3.37928  27.90117  12.44854  1.000 36.84573  ? 206 PRO B CA     1 
ATOM   3561 C  C      . PRO B 1  176 ? -4.85698  27.57774  12.28201  1.000 39.75247  ? 206 PRO B C      1 
ATOM   3562 O  O      . PRO B 1  176 ? -5.62810  27.90114  13.19294  1.000 43.64392  ? 206 PRO B O      1 
ATOM   3563 C  CB     . PRO B 1  176 ? -3.16501  29.42395  12.44177  1.000 39.97963  ? 206 PRO B CB     1 
ATOM   3564 C  CG     . PRO B 1  176 ? -2.87576  29.74380  11.01430  1.000 41.77625  ? 206 PRO B CG     1 
ATOM   3565 C  CD     . PRO B 1  176 ? -2.04159  28.58038  10.51805  1.000 40.15432  ? 206 PRO B CD     1 
ATOM   3566 N  N      . TRP B 1  177 ? -5.29838  26.96059  11.18662  1.000 34.75861  ? 207 TRP B N      1 
ATOM   3567 C  CA     . TRP B 1  177 ? -6.72623  26.74638  10.98907  1.000 37.32729  ? 207 TRP B CA     1 
ATOM   3568 C  C      . TRP B 1  177 ? -7.11124  25.29068  11.24484  1.000 35.25981  ? 207 TRP B C      1 
ATOM   3569 O  O      . TRP B 1  177 ? -6.26362  24.39485  11.31645  1.000 34.85617  ? 207 TRP B O      1 
ATOM   3570 C  CB     . TRP B 1  177 ? -7.15871  27.18262  9.57875   1.000 36.77328  ? 207 TRP B CB     1 
ATOM   3571 C  CG     . TRP B 1  177 ? -6.92706  28.66074  9.35648   1.000 36.37082  ? 207 TRP B CG     1 
ATOM   3572 C  CD1    . TRP B 1  177 ? -7.64128  29.69078  9.89634   1.000 36.22730  ? 207 TRP B CD1    1 
ATOM   3573 C  CD2    . TRP B 1  177 ? -5.88647  29.25857  8.57770   1.000 34.18659  ? 207 TRP B CD2    1 
ATOM   3574 N  NE1    . TRP B 1  177 ? -7.11778  30.89814  9.48679   1.000 40.65956  ? 207 TRP B NE1    1 
ATOM   3575 C  CE2    . TRP B 1  177 ? -6.03436  30.65793  8.68310   1.000 35.48387  ? 207 TRP B CE2    1 
ATOM   3576 C  CE3    . TRP B 1  177 ? -4.83759  28.74844  7.80600   1.000 37.07464  ? 207 TRP B CE3    1 
ATOM   3577 C  CZ2    . TRP B 1  177 ? -5.18918  31.54757  8.02987   1.000 34.93684  ? 207 TRP B CZ2    1 
ATOM   3578 C  CZ3    . TRP B 1  177 ? -3.99330  29.63983  7.15882   1.000 38.07581  ? 207 TRP B CZ3    1 
ATOM   3579 C  CH2    . TRP B 1  177 ? -4.17536  31.02422  7.27853   1.000 33.48374  ? 207 TRP B CH2    1 
ATOM   3580 N  N      . ASP B 1  178 ? -8.42252  25.08113  11.40463  1.000 40.12937  ? 208 ASP B N      1 
ATOM   3581 C  CA     . ASP B 1  178 ? -8.98083  23.80195  11.83477  1.000 44.92547  ? 208 ASP B CA     1 
ATOM   3582 C  C      . ASP B 1  178 ? -8.95110  22.75077  10.73741  1.000 44.74741  ? 208 ASP B C      1 
ATOM   3583 O  O      . ASP B 1  178 ? -8.99081  21.55453  11.03875  1.000 38.56622  ? 208 ASP B O      1 
ATOM   3584 C  CB     . ASP B 1  178 ? -10.43395 23.98554  12.28433  1.000 49.93018  ? 208 ASP B CB     1 
ATOM   3585 C  CG     . ASP B 1  178 ? -10.55888 24.82217  13.53549  1.000 59.83145  ? 208 ASP B CG     1 
ATOM   3586 O  OD1    . ASP B 1  178 ? -9.51998  25.11629  14.16921  1.000 55.03570  ? 208 ASP B OD1    1 
ATOM   3587 O  OD2    . ASP B 1  178 ? -11.70171 25.19595  13.87915  1.000 67.22106  ? 208 ASP B OD2    1 
ATOM   3588 N  N      . ARG B 1  179 ? -8.91087  23.16850  9.47919   1.000 36.99640  ? 209 ARG B N      1 
ATOM   3589 C  CA     . ARG B 1  179 ? -9.09302  22.27280  8.35184   1.000 38.07494  ? 209 ARG B CA     1 
ATOM   3590 C  C      . ARG B 1  179 ? -8.00159  22.51374  7.32406   1.000 37.15179  ? 209 ARG B C      1 
ATOM   3591 O  O      . ARG B 1  179 ? -7.49525  23.63062  7.18430   1.000 36.02521  ? 209 ARG B O      1 
ATOM   3592 C  CB     . ARG B 1  179 ? -10.46506 22.52181  7.72030   1.000 42.38192  ? 209 ARG B CB     1 
ATOM   3593 C  CG     . ARG B 1  179 ? -11.63716 22.11164  8.60209   1.000 52.09711  ? 209 ARG B CG     1 
ATOM   3594 C  CD     . ARG B 1  179 ? -12.98038 22.36601  7.92007   1.000 72.55362  ? 209 ARG B CD     1 
ATOM   3595 N  NE     . ARG B 1  179 ? -13.28402 23.79624  7.86355   1.000 85.42054  ? 209 ARG B NE     1 
ATOM   3596 C  CZ     . ARG B 1  179 ? -13.74613 24.50142  8.89091   1.000 84.74960  ? 209 ARG B CZ     1 
ATOM   3597 N  NH1    . ARG B 1  179 ? -13.84237 23.97599  10.10274  1.000 97.40056  ? 209 ARG B NH1    1 
ATOM   3598 N  NH2    . ARG B 1  179 ? -14.08433 25.77534  8.70757   1.000 76.12595  ? 209 ARG B NH2    1 
ATOM   3599 N  N      . TYR B 1  180 ? -7.64287  21.44980  6.60339   1.000 32.05588  ? 210 TYR B N      1 
ATOM   3600 C  CA     . TYR B 1  180 ? -6.77234  21.56894  5.44698   1.000 29.13191  ? 210 TYR B CA     1 
ATOM   3601 C  C      . TYR B 1  180 ? -7.61888  21.84981  4.21047   1.000 34.64407  ? 210 TYR B C      1 
ATOM   3602 O  O      . TYR B 1  180 ? -8.82572  21.58614  4.20072   1.000 35.35949  ? 210 TYR B O      1 
ATOM   3603 C  CB     . TYR B 1  180 ? -5.96491  20.29167  5.25377   1.000 31.55020  ? 210 TYR B CB     1 
ATOM   3604 C  CG     . TYR B 1  180 ? -4.74184  20.18249  6.13918   1.000 33.89572  ? 210 TYR B CG     1 
ATOM   3605 C  CD1    . TYR B 1  180 ? -4.00942  21.31112  6.48319   1.000 28.75295  ? 210 TYR B CD1    1 
ATOM   3606 C  CD2    . TYR B 1  180 ? -4.30622  18.94993  6.60911   1.000 33.58232  ? 210 TYR B CD2    1 
ATOM   3607 C  CE1    . TYR B 1  180 ? -2.88408  21.21945  7.28685   1.000 34.80646  ? 210 TYR B CE1    1 
ATOM   3608 C  CE2    . TYR B 1  180 ? -3.17567  18.85128  7.40526   1.000 29.91534  ? 210 TYR B CE2    1 
ATOM   3609 C  CZ     . TYR B 1  180 ? -2.47450  19.98809  7.74471   1.000 31.58216  ? 210 TYR B CZ     1 
ATOM   3610 O  OH     . TYR B 1  180 ? -1.35215  19.87926  8.52870   1.000 32.57263  ? 210 TYR B OH     1 
ATOM   3611 N  N      . PRO B 1  181 ? -7.03939  22.41795  3.15964   1.000 32.37038  ? 211 PRO B N      1 
ATOM   3612 C  CA     . PRO B 1  181 ? -7.76393  22.50639  1.89614   1.000 34.10182  ? 211 PRO B CA     1 
ATOM   3613 C  C      . PRO B 1  181 ? -7.92669  21.11520  1.32135   1.000 34.01832  ? 211 PRO B C      1 
ATOM   3614 O  O      . PRO B 1  181 ? -7.30791  20.16398  1.82923   1.000 31.82314  ? 211 PRO B O      1 
ATOM   3615 C  CB     . PRO B 1  181 ? -6.83094  23.34965  1.02292   1.000 32.32544  ? 211 PRO B CB     1 
ATOM   3616 C  CG     . PRO B 1  181 ? -5.48694  22.96922  1.49656   1.000 30.14935  ? 211 PRO B CG     1 
ATOM   3617 C  CD     . PRO B 1  181 ? -5.63834  22.84070  3.00129   1.000 28.37702  ? 211 PRO B CD     1 
ATOM   3618 N  N      . PRO B 1  182 ? -8.71072  20.95413  0.25777   1.000 31.89777  ? 212 PRO B N      1 
ATOM   3619 C  CA     . PRO B 1  182 ? -8.66080  19.68809  -0.48544  1.000 31.21963  ? 212 PRO B CA     1 
ATOM   3620 C  C      . PRO B 1  182 ? -7.26094  19.52096  -1.05128  1.000 27.56524  ? 212 PRO B C      1 
ATOM   3621 O  O      . PRO B 1  182 ? -6.65081  20.48049  -1.51808  1.000 28.81036  ? 212 PRO B O      1 
ATOM   3622 C  CB     . PRO B 1  182 ? -9.69838  19.87822  -1.60980  1.000 30.09536  ? 212 PRO B CB     1 
ATOM   3623 C  CG     . PRO B 1  182 ? -10.49354 21.08027  -1.22041  1.000 33.04286  ? 212 PRO B CG     1 
ATOM   3624 C  CD     . PRO B 1  182 ? -9.59192  21.94380  -0.39113  1.000 28.08037  ? 212 PRO B CD     1 
ATOM   3625 N  N      . PHE B 1  183 ? -6.73264  18.30380  -0.98873  1.000 26.54447  ? 213 PHE B N      1 
ATOM   3626 C  CA     . PHE B 1  183 ? -5.46626  18.03492  -1.64886  1.000 27.92738  ? 213 PHE B CA     1 
ATOM   3627 C  C      . PHE B 1  183 ? -5.42410  16.55377  -1.98287  1.000 29.81020  ? 213 PHE B C      1 
ATOM   3628 O  O      . PHE B 1  183 ? -6.32582  15.79219  -1.62584  1.000 33.60248  ? 213 PHE B O      1 
ATOM   3629 C  CB     . PHE B 1  183 ? -4.26286  18.48019  -0.79873  1.000 28.78628  ? 213 PHE B CB     1 
ATOM   3630 C  CG     . PHE B 1  183 ? -4.05928  17.67902  0.46862   1.000 30.54066  ? 213 PHE B CG     1 
ATOM   3631 C  CD1    . PHE B 1  183 ? -4.81745  17.95537  1.60197   1.000 36.67905  ? 213 PHE B CD1    1 
ATOM   3632 C  CD2    . PHE B 1  183 ? -3.08110  16.69866  0.54361   1.000 31.85584  ? 213 PHE B CD2    1 
ATOM   3633 C  CE1    . PHE B 1  183 ? -4.63561  17.23568  2.78440   1.000 36.28932  ? 213 PHE B CE1    1 
ATOM   3634 C  CE2    . PHE B 1  183 ? -2.88116  15.97243  1.73224   1.000 32.33501  ? 213 PHE B CE2    1 
ATOM   3635 C  CZ     . PHE B 1  183 ? -3.66968  16.24364  2.84652   1.000 34.04310  ? 213 PHE B CZ     1 
ATOM   3636 N  N      . CYS B 1  184 ? -4.38386  16.16567  -2.70664  1.000 29.53212  ? 214 CYS B N      1 
ATOM   3637 C  CA     . CYS B 1  184 ? -4.15595  14.77876  -3.09706  1.000 29.91136  ? 214 CYS B CA     1 
ATOM   3638 C  C      . CYS B 1  184 ? -2.92259  14.24813  -2.38557  1.000 30.24416  ? 214 CYS B C      1 
ATOM   3639 O  O      . CYS B 1  184 ? -1.91892  14.95290  -2.27595  1.000 28.03059  ? 214 CYS B O      1 
ATOM   3640 C  CB     . CYS B 1  184 ? -3.92881  14.65035  -4.60414  1.000 31.41351  ? 214 CYS B CB     1 
ATOM   3641 S  SG     . CYS B 1  184 ? -5.34184  15.06143  -5.66745  1.000 34.40238  ? 214 CYS B SG     1 
ATOM   3642 N  N      . SER B 1  185 ? -2.97554  12.97131  -1.99391  1.000 30.75880  ? 215 SER B N      1 
ATOM   3643 C  CA     . SER B 1  185 ? -1.86197  12.32711  -1.30818  1.000 34.17275  ? 215 SER B CA     1 
ATOM   3644 C  C      . SER B 1  185 ? -0.55596  12.56530  -2.04633  1.000 34.01446  ? 215 SER B C      1 
ATOM   3645 O  O      . SER B 1  185 ? -0.47940  12.40835  -3.26733  1.000 31.20086  ? 215 SER B O      1 
ATOM   3646 C  CB     . SER B 1  185 ? -2.12614  10.82183  -1.19126  1.000 30.24897  ? 215 SER B CB     1 
ATOM   3647 O  OG     . SER B 1  185 ? -0.97876  10.13544  -0.72493  1.000 33.26698  ? 215 SER B OG     1 
ATOM   3648 N  N      . GLY B 1  186 ? 0.47090   12.95981  -1.29302  1.000 27.89522  ? 216 GLY B N      1 
ATOM   3649 C  CA     . GLY B 1  186 ? 1.79501   13.17646  -1.83649  1.000 29.16092  ? 216 GLY B CA     1 
ATOM   3650 C  C      . GLY B 1  186 ? 2.49909   11.93901  -2.34640  1.000 29.03131  ? 216 GLY B C      1 
ATOM   3651 O  O      . GLY B 1  186 ? 3.54755   12.07660  -2.98985  1.000 35.90297  ? 216 GLY B O      1 
ATOM   3652 N  N      . THR B 1  187 ? 1.98285   10.74121  -2.06018  1.000 30.27462  ? 217 THR B N      1 
ATOM   3653 C  CA     . THR B 1  187 ? 2.61952   9.54294   -2.60344  1.000 34.20167  ? 217 THR B CA     1 
ATOM   3654 C  C      . THR B 1  187 ? 2.64659   9.56260   -4.12602  1.000 36.25193  ? 217 THR B C      1 
ATOM   3655 O  O      . THR B 1  187 ? 3.55745   8.99151   -4.73344  1.000 36.24921  ? 217 THR B O      1 
ATOM   3656 C  CB     . THR B 1  187 ? 1.92880   8.27399   -2.09873  1.000 32.28230  ? 217 THR B CB     1 
ATOM   3657 O  OG1    . THR B 1  187 ? 0.53905   8.31046   -2.41595  1.000 31.90889  ? 217 THR B OG1    1 
ATOM   3658 C  CG2    . THR B 1  187 ? 2.10354   8.14785   -0.58766  1.000 38.94796  ? 217 THR B CG2    1 
ATOM   3659 N  N      . GLY B 1  188 ? 1.67099   10.20707  -4.75788  1.000 33.65642  ? 218 GLY B N      1 
ATOM   3660 C  CA     . GLY B 1  188 ? 1.64883   10.26313  -6.21173  1.000 34.17752  ? 218 GLY B CA     1 
ATOM   3661 C  C      . GLY B 1  188 ? 0.45690   11.03376  -6.73181  1.000 27.92295  ? 218 GLY B C      1 
ATOM   3662 O  O      . GLY B 1  188 ? -0.69031  10.66081  -6.48149  1.000 32.46834  ? 218 GLY B O      1 
ATOM   3663 N  N      . TYR B 1  189 ? 0.70801   12.15801  -7.39537  1.000 32.51017  ? 219 TYR B N      1 
ATOM   3664 C  CA     . TYR B 1  189 ? -0.37835  12.91243  -8.00486  1.000 32.33449  ? 219 TYR B CA     1 
ATOM   3665 C  C      . TYR B 1  189 ? 0.03517   13.38358  -9.39480  1.000 31.93789  ? 219 TYR B C      1 
ATOM   3666 O  O      . TYR B 1  189 ? 1.21793   13.37763  -9.74828  1.000 32.51656  ? 219 TYR B O      1 
ATOM   3667 C  CB     . TYR B 1  189 ? -0.83532  14.07870  -7.12131  1.000 29.05881  ? 219 TYR B CB     1 
ATOM   3668 C  CG     . TYR B 1  189 ? 0.24650   14.99925  -6.59551  1.000 33.69175  ? 219 TYR B CG     1 
ATOM   3669 C  CD1    . TYR B 1  189 ? 0.83569   15.96916  -7.40724  1.000 36.59178  ? 219 TYR B CD1    1 
ATOM   3670 C  CD2    . TYR B 1  189 ? 0.63824   14.94173  -5.25895  1.000 35.00667  ? 219 TYR B CD2    1 
ATOM   3671 C  CE1    . TYR B 1  189 ? 1.81015   16.83464  -6.90130  1.000 34.29879  ? 219 TYR B CE1    1 
ATOM   3672 C  CE2    . TYR B 1  189 ? 1.61052   15.79978  -4.75053  1.000 32.63464  ? 219 TYR B CE2    1 
ATOM   3673 C  CZ     . TYR B 1  189 ? 2.18956   16.74168  -5.56778  1.000 38.96659  ? 219 TYR B CZ     1 
ATOM   3674 O  OH     . TYR B 1  189 ? 3.15511   17.58586  -5.04797  1.000 31.99170  ? 219 TYR B OH     1 
ATOM   3675 N  N      . VAL B 1  190 ? -0.96664  13.75044  -10.19737 1.000 28.99206  ? 220 VAL B N      1 
ATOM   3676 C  CA     . VAL B 1  190 ? -0.76948  14.05613  -11.61264 1.000 32.21138  ? 220 VAL B CA     1 
ATOM   3677 C  C      . VAL B 1  190 ? -1.48892  15.35060  -11.96419 1.000 25.10629  ? 220 VAL B C      1 
ATOM   3678 O  O      . VAL B 1  190 ? -2.58330  15.62435  -11.45896 1.000 30.26174  ? 220 VAL B O      1 
ATOM   3679 C  CB     . VAL B 1  190 ? -1.26588  12.90701  -12.51052 1.000 28.06717  ? 220 VAL B CB     1 
ATOM   3680 C  CG1    . VAL B 1  190 ? -0.92478  13.19220  -13.94474 1.000 31.31037  ? 220 VAL B CG1    1 
ATOM   3681 C  CG2    . VAL B 1  190 ? -0.64301  11.58407  -12.06391 1.000 29.79671  ? 220 VAL B CG2    1 
ATOM   3682 N  N      . PHE B 1  191 ? -0.88205  16.14672  -12.83860 1.000 33.45620  ? 221 PHE B N      1 
ATOM   3683 C  CA     . PHE B 1  191 ? -1.50319  17.39832  -13.25060 1.000 33.40107  ? 221 PHE B CA     1 
ATOM   3684 C  C      . PHE B 1  191 ? -1.10286  17.74966  -14.67869 1.000 32.75789  ? 221 PHE B C      1 
ATOM   3685 O  O      . PHE B 1  191 ? -0.01582  17.39145  -15.14007 1.000 34.12950  ? 221 PHE B O      1 
ATOM   3686 C  CB     . PHE B 1  191 ? -1.12272  18.54146  -12.30279 1.000 31.90002  ? 221 PHE B CB     1 
ATOM   3687 C  CG     . PHE B 1  191 ? 0.35295   18.64680  -12.03850 1.000 35.19605  ? 221 PHE B CG     1 
ATOM   3688 C  CD1    . PHE B 1  191 ? 0.94472   17.91331  -11.01433 1.000 36.52484  ? 221 PHE B CD1    1 
ATOM   3689 C  CD2    . PHE B 1  191 ? 1.15081   19.49237  -12.79796 1.000 38.27407  ? 221 PHE B CD2    1 
ATOM   3690 C  CE1    . PHE B 1  191 ? 2.31495   18.01213  -10.76373 1.000 35.35608  ? 221 PHE B CE1    1 
ATOM   3691 C  CE2    . PHE B 1  191 ? 2.51571   19.59882  -12.55036 1.000 34.70380  ? 221 PHE B CE2    1 
ATOM   3692 C  CZ     . PHE B 1  191 ? 3.09553   18.86233  -11.53093 1.000 40.19277  ? 221 PHE B CZ     1 
ATOM   3693 N  N      . SER B 1  192 ? -1.97841  18.48734  -15.36427 1.000 34.33306  ? 222 SER B N      1 
ATOM   3694 C  CA     . SER B 1  192 ? -1.61856  18.99092  -16.68868 1.000 43.86527  ? 222 SER B CA     1 
ATOM   3695 C  C      . SER B 1  192 ? -0.45318  19.96714  -16.56593 1.000 38.69939  ? 222 SER B C      1 
ATOM   3696 O  O      . SER B 1  192 ? -0.29787  20.65523  -15.55447 1.000 39.88006  ? 222 SER B O      1 
ATOM   3697 C  CB     . SER B 1  192 ? -2.81739  19.65660  -17.38295 1.000 39.19719  ? 222 SER B CB     1 
ATOM   3698 O  OG     . SER B 1  192 ? -3.53400  20.54760  -16.53715 1.000 35.80748  ? 222 SER B OG     1 
ATOM   3699 N  N      . GLY B 1  193 ? 0.40617   19.98398  -17.58841 1.000 40.94153  ? 223 GLY B N      1 
ATOM   3700 C  CA     . GLY B 1  193 ? 1.65238   20.73607  -17.49656 1.000 35.19022  ? 223 GLY B CA     1 
ATOM   3701 C  C      . GLY B 1  193 ? 1.47560   22.21565  -17.17732 1.000 42.10101  ? 223 GLY B C      1 
ATOM   3702 O  O      . GLY B 1  193 ? 2.30264   22.80268  -16.47593 1.000 39.44754  ? 223 GLY B O      1 
ATOM   3703 N  N      . ASP B 1  194 ? 0.40232   22.83992  -17.67772 1.000 41.16966  ? 224 ASP B N      1 
ATOM   3704 C  CA     . ASP B 1  194 ? 0.16295   24.26131  -17.39792 1.000 44.59746  ? 224 ASP B CA     1 
ATOM   3705 C  C      . ASP B 1  194 ? 0.05348   24.55207  -15.89893 1.000 50.52167  ? 224 ASP B C      1 
ATOM   3706 O  O      . ASP B 1  194 ? 0.40518   25.66171  -15.43097 1.000 43.87324  ? 224 ASP B O      1 
ATOM   3707 C  CB     . ASP B 1  194 ? -1.11708  24.70434  -18.10104 1.000 41.50110  ? 224 ASP B CB     1 
ATOM   3708 C  CG     . ASP B 1  194 ? -2.32722  23.89002  -17.67533 1.000 39.35625  ? 224 ASP B CG     1 
ATOM   3709 O  OD1    . ASP B 1  194 ? -2.25814  22.64094  -17.72221 1.000 39.26507  ? 224 ASP B OD1    1 
ATOM   3710 O  OD2    . ASP B 1  194 ? -3.34977  24.48880  -17.28349 1.000 42.36676  ? 224 ASP B OD2    1 
ATOM   3711 N  N      . VAL B 1  195 ? -0.45308  23.57872  -15.13337 1.000 42.26341  ? 225 VAL B N      1 
ATOM   3712 C  CA     . VAL B 1  195 ? -0.60569  23.77650  -13.69598 1.000 43.10973  ? 225 VAL B CA     1 
ATOM   3713 C  C      . VAL B 1  195 ? 0.73839   24.06841  -13.04379 1.000 37.28751  ? 225 VAL B C      1 
ATOM   3714 O  O      . VAL B 1  195 ? 0.79746   24.78403  -12.03810 1.000 41.36568  ? 225 VAL B O      1 
ATOM   3715 C  CB     . VAL B 1  195 ? -1.29811  22.56219  -13.04633 1.000 39.86365  ? 225 VAL B CB     1 
ATOM   3716 C  CG1    . VAL B 1  195 ? -1.29818  22.70500  -11.53378 1.000 38.51350  ? 225 VAL B CG1    1 
ATOM   3717 C  CG2    . VAL B 1  195 ? -2.72894  22.43795  -13.55404 1.000 37.77284  ? 225 VAL B CG2    1 
ATOM   3718 N  N      . ALA B 1  196 ? 1.83314   23.50746  -13.57273 1.000 35.52588  ? 226 ALA B N      1 
ATOM   3719 C  CA     . ALA B 1  196 ? 3.14026   23.75975  -12.97251 1.000 33.90406  ? 226 ALA B CA     1 
ATOM   3720 C  C      . ALA B 1  196 ? 3.44017   25.24890  -12.93969 1.000 43.70653  ? 226 ALA B C      1 
ATOM   3721 O  O      . ALA B 1  196 ? 3.85756   25.79738  -11.90816 1.000 40.50243  ? 226 ALA B O      1 
ATOM   3722 C  CB     . ALA B 1  196 ? 4.23331   23.02808  -13.74273 1.000 34.35178  ? 226 ALA B CB     1 
ATOM   3723 N  N      . SER B 1  197 ? 3.23051   25.92404  -14.06986 1.000 48.64952  ? 227 SER B N      1 
ATOM   3724 C  CA     . SER B 1  197 ? 3.49251   27.35503  -14.11242 1.000 46.80233  ? 227 SER B CA     1 
ATOM   3725 C  C      . SER B 1  197 ? 2.52752   28.10815  -13.21399 1.000 40.29260  ? 227 SER B C      1 
ATOM   3726 O  O      . SER B 1  197 ? 2.93513   29.04255  -12.51294 1.000 48.27239  ? 227 SER B O      1 
ATOM   3727 C  CB     . SER B 1  197 ? 3.43105   27.86665  -15.55180 1.000 48.58159  ? 227 SER B CB     1 
ATOM   3728 O  OG     . SER B 1  197 ? 4.55625   27.40813  -16.28468 1.000 55.59064  ? 227 SER B OG     1 
ATOM   3729 N  N      . GLN B 1  198 ? 1.24754   27.71393  -13.19973 1.000 38.16935  ? 228 GLN B N      1 
ATOM   3730 C  CA     . GLN B 1  198 ? 0.30644   28.46146  -12.35666 1.000 36.01964  ? 228 GLN B CA     1 
ATOM   3731 C  C      . GLN B 1  198 ? 0.63664   28.32708  -10.86239 1.000 45.12341  ? 228 GLN B C      1 
ATOM   3732 O  O      . GLN B 1  198 ? 0.62560   29.32537  -10.11956 1.000 42.77393  ? 228 GLN B O      1 
ATOM   3733 C  CB     . GLN B 1  198 ? -1.13582  28.04756  -12.64343 1.000 42.40918  ? 228 GLN B CB     1 
ATOM   3734 C  CG     . GLN B 1  198 ? -1.65313  28.52816  -14.00742 1.000 44.45370  ? 228 GLN B CG     1 
ATOM   3735 C  CD     . GLN B 1  198 ? -3.00469  27.94421  -14.37120 1.000 55.99766  ? 228 GLN B CD     1 
ATOM   3736 O  OE1    . GLN B 1  198 ? -4.01755  28.24587  -13.73544 1.000 53.82442  ? 228 GLN B OE1    1 
ATOM   3737 N  NE2    . GLN B 1  198 ? -3.03473  27.12866  -15.42120 1.000 55.78708  ? 228 GLN B NE2    1 
ATOM   3738 N  N      . VAL B 1  199 ? 0.94827   27.11029  -10.40438 1.000 38.62409  ? 229 VAL B N      1 
ATOM   3739 C  CA     . VAL B 1  199 ? 1.30909   26.91263  -8.99994  1.000 36.67599  ? 229 VAL B CA     1 
ATOM   3740 C  C      . VAL B 1  199 ? 2.59431   27.65549  -8.66721  1.000 39.07520  ? 229 VAL B C      1 
ATOM   3741 O  O      . VAL B 1  199 ? 2.69906   28.29755  -7.61489  1.000 44.24601  ? 229 VAL B O      1 
ATOM   3742 C  CB     . VAL B 1  199 ? 1.43910   25.41635  -8.66393  1.000 38.15199  ? 229 VAL B CB     1 
ATOM   3743 C  CG1    . VAL B 1  199 ? 2.18765   25.26425  -7.33122  1.000 35.83191  ? 229 VAL B CG1    1 
ATOM   3744 C  CG2    . VAL B 1  199 ? 0.06777   24.78372  -8.57525  1.000 35.49548  ? 229 VAL B CG2    1 
ATOM   3745 N  N      . TYR B 1  200 ? 3.61741   27.53323  -9.52184  1.000 41.63409  ? 230 TYR B N      1 
ATOM   3746 C  CA     . TYR B 1  200 ? 4.85388   28.26548  -9.26762  1.000 40.77545  ? 230 TYR B CA     1 
ATOM   3747 C  C      . TYR B 1  200 ? 4.59042   29.76238  -9.16274  1.000 49.45818  ? 230 TYR B C      1 
ATOM   3748 O  O      . TYR B 1  200 ? 5.17759   30.44746  -8.31547  1.000 45.97322  ? 230 TYR B O      1 
ATOM   3749 C  CB     . TYR B 1  200 ? 5.87595   27.98320  -10.36753 1.000 47.70813  ? 230 TYR B CB     1 
ATOM   3750 C  CG     . TYR B 1  200 ? 7.17812   28.73760  -10.18860 1.000 55.22105  ? 230 TYR B CG     1 
ATOM   3751 C  CD1    . TYR B 1  200 ? 8.13398   28.32003  -9.27106  1.000 56.75005  ? 230 TYR B CD1    1 
ATOM   3752 C  CD2    . TYR B 1  200 ? 7.43365   29.89261  -10.91986 1.000 57.66902  ? 230 TYR B CD2    1 
ATOM   3753 C  CE1    . TYR B 1  200 ? 9.32140   29.01750  -9.10568  1.000 60.59615  ? 230 TYR B CE1    1 
ATOM   3754 C  CE2    . TYR B 1  200 ? 8.61557   30.59596  -10.76110 1.000 65.85734  ? 230 TYR B CE2    1 
ATOM   3755 C  CZ     . TYR B 1  200 ? 9.55635   30.15417  -9.85188  1.000 68.29297  ? 230 TYR B CZ     1 
ATOM   3756 O  OH     . TYR B 1  200 ? 10.73541  30.84677  -9.68461  1.000 67.43530  ? 230 TYR B OH     1 
ATOM   3757 N  N      . ASN B 1  201 ? 3.70161   30.28112  -10.01275 1.000 49.15130  ? 231 ASN B N      1 
ATOM   3758 C  CA     . ASN B 1  201 ? 3.37666   31.70125  -10.00344 1.000 55.15765  ? 231 ASN B CA     1 
ATOM   3759 C  C      . ASN B 1  201 ? 2.76617   32.11182  -8.67295  1.000 56.29033  ? 231 ASN B C      1 
ATOM   3760 O  O      . ASN B 1  201 ? 3.15877   33.12104  -8.07720  1.000 59.68394  ? 231 ASN B O      1 
ATOM   3761 C  CB     . ASN B 1  201 ? 2.39679   31.99967  -11.13763 1.000 66.18198  ? 231 ASN B CB     1 
ATOM   3762 C  CG     . ASN B 1  201 ? 2.09369   33.47489  -11.28626 1.000 94.38923  ? 231 ASN B CG     1 
ATOM   3763 O  OD1    . ASN B 1  201 ? 1.04491   33.95602  -10.85764 1.000 98.01260  ? 231 ASN B OD1    1 
ATOM   3764 N  ND2    . ASN B 1  201 ? 3.00461   34.19040  -11.93582 1.000 114.55724 ? 231 ASN B ND2    1 
ATOM   3765 N  N      . VAL B 1  202 ? 1.80232   31.32969  -8.18208  1.000 45.06909  ? 232 VAL B N      1 
ATOM   3766 C  CA     . VAL B 1  202 ? 1.06763   31.74145  -6.98625  1.000 46.80937  ? 232 VAL B CA     1 
ATOM   3767 C  C      . VAL B 1  202 ? 1.76979   31.35208  -5.68693  1.000 43.24887  ? 232 VAL B C      1 
ATOM   3768 O  O      . VAL B 1  202 ? 1.39061   31.85606  -4.61923  1.000 42.48211  ? 232 VAL B O      1 
ATOM   3769 C  CB     . VAL B 1  202 ? -0.36389  31.16148  -7.01811  1.000 41.04084  ? 232 VAL B CB     1 
ATOM   3770 C  CG1    . VAL B 1  202 ? -0.33932  29.66707  -6.72904  1.000 40.10572  ? 232 VAL B CG1    1 
ATOM   3771 C  CG2    . VAL B 1  202 ? -1.27357  31.88535  -6.04842  1.000 44.83878  ? 232 VAL B CG2    1 
ATOM   3772 N  N      . SER B 1  203 ? 2.78032   30.47994  -5.74369  1.000 42.04085  ? 233 SER B N      1 
ATOM   3773 C  CA     . SER B 1  203 ? 3.32767   29.86464  -4.53525  1.000 41.43557  ? 233 SER B CA     1 
ATOM   3774 C  C      . SER B 1  203 ? 3.81104   30.89292  -3.50312  1.000 51.28802  ? 233 SER B C      1 
ATOM   3775 O  O      . SER B 1  203 ? 3.53965   30.74747  -2.30408  1.000 44.75771  ? 233 SER B O      1 
ATOM   3776 C  CB     . SER B 1  203 ? 4.44255   28.88932  -4.91901  1.000 40.60641  ? 233 SER B CB     1 
ATOM   3777 O  OG     . SER B 1  203 ? 5.51206   29.53829  -5.58005  1.000 39.99497  ? 233 SER B OG     1 
ATOM   3778 N  N      . LYS B 1  204 ? 4.55201   31.92440  -3.92989  1.000 49.40280  ? 234 LYS B N      1 
ATOM   3779 C  CA     . LYS B 1  204 ? 5.10468   32.83018  -2.91797  1.000 42.14536  ? 234 LYS B CA     1 
ATOM   3780 C  C      . LYS B 1  204 ? 4.05625   33.72720  -2.26079  1.000 44.02088  ? 234 LYS B C      1 
ATOM   3781 O  O      . LYS B 1  204 ? 4.39799   34.44419  -1.31066  1.000 48.07866  ? 234 LYS B O      1 
ATOM   3782 C  CB     . LYS B 1  204 ? 6.24754   33.68610  -3.47477  1.000 46.51820  ? 234 LYS B CB     1 
ATOM   3783 C  CG     . LYS B 1  204 ? 7.57317   32.93955  -3.57592  1.000 46.34215  ? 234 LYS B CG     1 
ATOM   3784 C  CD     . LYS B 1  204 ? 8.53861   33.58244  -4.56150  1.000 59.09765  ? 234 LYS B CD     1 
ATOM   3785 C  CE     . LYS B 1  204 ? 9.89517   33.88950  -3.90545  1.000 69.95382  ? 234 LYS B CE     1 
ATOM   3786 N  NZ     . LYS B 1  204 ? 9.85959   35.01616  -2.91683  1.000 53.96150  ? 234 LYS B NZ     1 
ATOM   3787 N  N      . SER B 1  205 ? 2.80454   33.72143  -2.72194  1.000 41.24422  ? 235 SER B N      1 
ATOM   3788 C  CA     . SER B 1  205 ? 1.75550   34.46919  -2.04041  1.000 38.30760  ? 235 SER B CA     1 
ATOM   3789 C  C      . SER B 1  205 ? 0.88384   33.57750  -1.16938  1.000 44.27921  ? 235 SER B C      1 
ATOM   3790 O  O      . SER B 1  205 ? -0.02578  34.08135  -0.49934  1.000 41.84630  ? 235 SER B O      1 
ATOM   3791 C  CB     . SER B 1  205 ? 0.85822   35.21091  -3.03795  1.000 42.30036  ? 235 SER B CB     1 
ATOM   3792 O  OG     . SER B 1  205 ? -0.06709  34.32836  -3.65206  1.000 51.44988  ? 235 SER B OG     1 
ATOM   3793 N  N      . VAL B 1  206 ? 1.11605   32.26815  -1.19468  1.000 44.80788  ? 236 VAL B N      1 
ATOM   3794 C  CA     . VAL B 1  206 ? 0.32332   31.29737  -0.44746  1.000 39.06380  ? 236 VAL B CA     1 
ATOM   3795 C  C      . VAL B 1  206 ? 1.04779   30.94610  0.85062   1.000 33.23099  ? 236 VAL B C      1 
ATOM   3796 O  O      . VAL B 1  206 ? 2.26214   30.70103  0.84218   1.000 33.91120  ? 236 VAL B O      1 
ATOM   3797 C  CB     . VAL B 1  206 ? 0.05686   30.04458  -1.30244  1.000 40.92897  ? 236 VAL B CB     1 
ATOM   3798 C  CG1    . VAL B 1  206 ? -0.55696  28.93785  -0.46168  1.000 35.78179  ? 236 VAL B CG1    1 
ATOM   3799 C  CG2    . VAL B 1  206 ? -0.84357  30.39380  -2.50061  1.000 36.45622  ? 236 VAL B CG2    1 
ATOM   3800 N  N      . PRO B 1  207 ? 0.34535   30.87073  1.97542   1.000 31.93746  ? 237 PRO B N      1 
ATOM   3801 C  CA     . PRO B 1  207 ? 1.01807   30.53861  3.24172   1.000 36.01325  ? 237 PRO B CA     1 
ATOM   3802 C  C      . PRO B 1  207 ? 1.76829   29.21381  3.14273   1.000 43.51473  ? 237 PRO B C      1 
ATOM   3803 O  O      . PRO B 1  207 ? 1.23237   28.20619  2.66472   1.000 39.83389  ? 237 PRO B O      1 
ATOM   3804 C  CB     . PRO B 1  207 ? -0.13840  30.47685  4.24481   1.000 36.70423  ? 237 PRO B CB     1 
ATOM   3805 C  CG     . PRO B 1  207 ? -1.21805  31.33133  3.63332   1.000 43.61775  ? 237 PRO B CG     1 
ATOM   3806 C  CD     . PRO B 1  207 ? -1.09946  31.09233  2.15011   1.000 36.22036  ? 237 PRO B CD     1 
ATOM   3807 N  N      . TYR B 1  208 ? 3.02471   29.23067  3.58744   1.000 38.45676  ? 238 TYR B N      1 
ATOM   3808 C  CA     . TYR B 1  208 ? 3.87866   28.05240  3.53612   1.000 43.29347  ? 238 TYR B CA     1 
ATOM   3809 C  C      . TYR B 1  208 ? 3.48597   27.01369  4.58814   1.000 43.27853  ? 238 TYR B C      1 
ATOM   3810 O  O      . TYR B 1  208 ? 3.07980   27.34824  5.70602   1.000 41.63709  ? 238 TYR B O      1 
ATOM   3811 C  CB     . TYR B 1  208 ? 5.34098   28.45948  3.72691   1.000 40.79680  ? 238 TYR B CB     1 
ATOM   3812 C  CG     . TYR B 1  208 ? 6.29861   27.29955  3.90398   1.000 44.04884  ? 238 TYR B CG     1 
ATOM   3813 C  CD1    . TYR B 1  208 ? 6.54371   26.76354  5.16433   1.000 46.27623  ? 238 TYR B CD1    1 
ATOM   3814 C  CD2    . TYR B 1  208 ? 6.97019   26.75001  2.82332   1.000 45.63306  ? 238 TYR B CD2    1 
ATOM   3815 C  CE1    . TYR B 1  208 ? 7.41207   25.70841  5.33748   1.000 44.84037  ? 238 TYR B CE1    1 
ATOM   3816 C  CE2    . TYR B 1  208 ? 7.85172   25.70090  2.98709   1.000 43.24710  ? 238 TYR B CE2    1 
ATOM   3817 C  CZ     . TYR B 1  208 ? 8.06584   25.18042  4.24705   1.000 45.62450  ? 238 TYR B CZ     1 
ATOM   3818 O  OH     . TYR B 1  208 ? 8.93578   24.12877  4.43029   1.000 52.56281  ? 238 TYR B OH     1 
ATOM   3819 N  N      . ILE B 1  209 ? 3.62599   25.74256  4.21832   1.000 40.52191  ? 239 ILE B N      1 
ATOM   3820 C  CA     . ILE B 1  209 ? 3.50086   24.61844  5.13977   1.000 34.74946  ? 239 ILE B CA     1 
ATOM   3821 C  C      . ILE B 1  209 ? 4.51768   23.56860  4.73418   1.000 39.06083  ? 239 ILE B C      1 
ATOM   3822 O  O      . ILE B 1  209 ? 4.77612   23.36945  3.54320   1.000 40.54100  ? 239 ILE B O      1 
ATOM   3823 C  CB     . ILE B 1  209 ? 2.07806   24.02618  5.14143   1.000 38.56226  ? 239 ILE B CB     1 
ATOM   3824 C  CG1    . ILE B 1  209 ? 1.92193   23.02823  6.29510   1.000 34.74418  ? 239 ILE B CG1    1 
ATOM   3825 C  CG2    . ILE B 1  209 ? 1.78233   23.32853  3.78861   1.000 31.82208  ? 239 ILE B CG2    1 
ATOM   3826 C  CD1    . ILE B 1  209 ? 0.51413   22.56223  6.50185   1.000 35.71161  ? 239 ILE B CD1    1 
ATOM   3827 N  N      . LYS B 1  210 ? 5.10556   22.89785  5.72680   1.000 35.45908  ? 240 LYS B N      1 
ATOM   3828 C  CA     . LYS B 1  210 ? 6.17104   21.94724  5.45184   1.000 35.41028  ? 240 LYS B CA     1 
ATOM   3829 C  C      . LYS B 1  210 ? 5.65850   20.62615  4.88215   1.000 32.96678  ? 240 LYS B C      1 
ATOM   3830 O  O      . LYS B 1  210 ? 6.47393   19.76410  4.54682   1.000 35.97741  ? 240 LYS B O      1 
ATOM   3831 C  CB     . LYS B 1  210 ? 6.97963   21.66457  6.72312   1.000 43.84451  ? 240 LYS B CB     1 
ATOM   3832 C  CG     . LYS B 1  210 ? 6.18088   20.99034  7.83517   1.000 40.86189  ? 240 LYS B CG     1 
ATOM   3833 C  CD     . LYS B 1  210 ? 7.04746   20.73399  9.06323   1.000 47.86543  ? 240 LYS B CD     1 
ATOM   3834 C  CE     . LYS B 1  210 ? 6.26378   20.02736  10.16128  1.000 51.34964  ? 240 LYS B CE     1 
ATOM   3835 N  NZ     . LYS B 1  210 ? 6.88855   20.21098  11.50217  1.000 57.21045  ? 240 LYS B NZ     1 
ATOM   3836 N  N      . LEU B 1  211 ? 4.34364   20.43278  4.81442   1.000 32.85627  ? 241 LEU B N      1 
ATOM   3837 C  CA     . LEU B 1  211 ? 3.75533   19.24355  4.19005   1.000 32.47648  ? 241 LEU B CA     1 
ATOM   3838 C  C      . LEU B 1  211 ? 3.45080   19.57315  2.72807   1.000 32.11875  ? 241 LEU B C      1 
ATOM   3839 O  O      . LEU B 1  211 ? 2.52643   20.33662  2.44364   1.000 29.40018  ? 241 LEU B O      1 
ATOM   3840 C  CB     . LEU B 1  211 ? 2.49982   18.81866  4.94582   1.000 32.94740  ? 241 LEU B CB     1 
ATOM   3841 C  CG     . LEU B 1  211 ? 2.77249   18.53833  6.43476   1.000 32.57930  ? 241 LEU B CG     1 
ATOM   3842 C  CD1    . LEU B 1  211 ? 1.49374   18.22561  7.17196   1.000 33.97699  ? 241 LEU B CD1    1 
ATOM   3843 C  CD2    . LEU B 1  211 ? 3.74658   17.39908  6.55215   1.000 34.33268  ? 241 LEU B CD2    1 
ATOM   3844 N  N      . GLU B 1  212 ? 4.21486   18.97805  1.80513   1.000 32.33364  ? 242 GLU B N      1 
ATOM   3845 C  CA     . GLU B 1  212 ? 4.19982   19.43206  0.41415   1.000 35.01456  ? 242 GLU B CA     1 
ATOM   3846 C  C      . GLU B 1  212 ? 2.83389   19.23987  -0.25341  1.000 37.55444  ? 242 GLU B C      1 
ATOM   3847 O  O      . GLU B 1  212 ? 2.37298   20.12087  -0.99718  1.000 33.71406  ? 242 GLU B O      1 
ATOM   3848 C  CB     . GLU B 1  212 ? 5.31389   18.73851  -0.38058  1.000 27.66911  ? 242 GLU B CB     1 
ATOM   3849 C  CG     . GLU B 1  212 ? 5.23918   17.20312  -0.47761  1.000 34.04838  ? 242 GLU B CG     1 
ATOM   3850 C  CD     . GLU B 1  212 ? 4.36887   16.72135  -1.63706  1.000 41.35194  ? 242 GLU B CD     1 
ATOM   3851 O  OE1    . GLU B 1  212 ? 4.23709   17.45030  -2.65418  1.000 35.18030  ? 242 GLU B OE1    1 
ATOM   3852 O  OE2    . GLU B 1  212 ? 3.80720   15.60851  -1.52697  1.000 33.43189  ? 242 GLU B OE2    1 
ATOM   3853 N  N      . ASP B 1  213 ? 2.15893   18.11187  0.00031   1.000 31.36402  ? 243 ASP B N      1 
ATOM   3854 C  CA     . ASP B 1  213 ? 0.88424   17.88226  -0.67613  1.000 31.54811  ? 243 ASP B CA     1 
ATOM   3855 C  C      . ASP B 1  213 ? -0.18374  18.85855  -0.18645  1.000 33.06189  ? 243 ASP B C      1 
ATOM   3856 O  O      . ASP B 1  213 ? -0.97433  19.38371  -0.98732  1.000 27.08193  ? 243 ASP B O      1 
ATOM   3857 C  CB     . ASP B 1  213 ? 0.43589   16.40972  -0.53709  1.000 26.64400  ? 243 ASP B CB     1 
ATOM   3858 C  CG     . ASP B 1  213 ? 0.56244   15.84945  0.89838   1.000 34.62218  ? 243 ASP B CG     1 
ATOM   3859 O  OD1    . ASP B 1  213 ? 0.86933   16.60219  1.85395   1.000 31.99887  ? 243 ASP B OD1    1 
ATOM   3860 O  OD2    . ASP B 1  213 ? 0.35423   14.62444  1.06065   1.000 34.22055  ? 243 ASP B OD2    1 
ATOM   3861 N  N      . VAL B 1  214 ? -0.17908  19.18010  1.10823   1.000 31.99572  ? 244 VAL B N      1 
ATOM   3862 C  CA     . VAL B 1  214 ? -1.08305  20.21494  1.60105   1.000 28.78528  ? 244 VAL B CA     1 
ATOM   3863 C  C      . VAL B 1  214 ? -0.75355  21.55918  0.96379   1.000 34.45313  ? 244 VAL B C      1 
ATOM   3864 O  O      . VAL B 1  214 ? -1.65419  22.31717  0.58112   1.000 27.87363  ? 244 VAL B O      1 
ATOM   3865 C  CB     . VAL B 1  214 ? -1.03265  20.32143  3.13680   1.000 34.93887  ? 244 VAL B CB     1 
ATOM   3866 C  CG1    . VAL B 1  214 ? -2.00164  21.38744  3.59674   1.000 26.07553  ? 244 VAL B CG1    1 
ATOM   3867 C  CG2    . VAL B 1  214 ? -1.35088  18.97984  3.79611   1.000 34.33851  ? 244 VAL B CG2    1 
ATOM   3868 N  N      . PHE B 1  215 ? 0.53301   21.89315  0.86842   1.000 29.12609  ? 245 PHE B N      1 
ATOM   3869 C  CA     . PHE B 1  215 ? 0.89069   23.18059  0.28893   1.000 30.90723  ? 245 PHE B CA     1 
ATOM   3870 C  C      . PHE B 1  215 ? 0.38095   23.29095  -1.14139  1.000 30.76472  ? 245 PHE B C      1 
ATOM   3871 O  O      . PHE B 1  215 ? -0.20736  24.30966  -1.53460  1.000 31.95265  ? 245 PHE B O      1 
ATOM   3872 C  CB     . PHE B 1  215 ? 2.39667   23.38829  0.32023   1.000 31.06755  ? 245 PHE B CB     1 
ATOM   3873 C  CG     . PHE B 1  215 ? 2.80144   24.69714  -0.27887  1.000 36.08208  ? 245 PHE B CG     1 
ATOM   3874 C  CD1    . PHE B 1  215 ? 2.49129   25.88121  0.36618   1.000 36.67021  ? 245 PHE B CD1    1 
ATOM   3875 C  CD2    . PHE B 1  215 ? 3.44130   24.74910  -1.50494  1.000 35.37277  ? 245 PHE B CD2    1 
ATOM   3876 C  CE1    . PHE B 1  215 ? 2.84160   27.10093  -0.18966  1.000 42.64875  ? 245 PHE B CE1    1 
ATOM   3877 C  CE2    . PHE B 1  215 ? 3.79201   25.96481  -2.06527  1.000 41.37516  ? 245 PHE B CE2    1 
ATOM   3878 C  CZ     . PHE B 1  215 ? 3.49593   27.13748  -1.40418  1.000 42.14985  ? 245 PHE B CZ     1 
ATOM   3879 N  N      . VAL B 1  216 ? 0.60950   22.24881  -1.94071  1.000 31.39672  ? 246 VAL B N      1 
ATOM   3880 C  CA     . VAL B 1  216 ? 0.09229   22.26466  -3.30432  1.000 28.38372  ? 246 VAL B CA     1 
ATOM   3881 C  C      . VAL B 1  216 ? -1.41615  22.44558  -3.28886  1.000 32.93106  ? 246 VAL B C      1 
ATOM   3882 O  O      . VAL B 1  216 ? -1.97134  23.20217  -4.09559  1.000 36.52785  ? 246 VAL B O      1 
ATOM   3883 C  CB     . VAL B 1  216 ? 0.52683   20.99606  -4.05305  1.000 33.33851  ? 246 VAL B CB     1 
ATOM   3884 C  CG1    . VAL B 1  216 ? -0.20969  20.87340  -5.39580  1.000 33.79243  ? 246 VAL B CG1    1 
ATOM   3885 C  CG2    . VAL B 1  216 ? 2.03236   21.05083  -4.27722  1.000 30.46662  ? 246 VAL B CG2    1 
ATOM   3886 N  N      . GLY B 1  217 ? -2.10431  21.76580  -2.37059  1.000 29.41931  ? 247 GLY B N      1 
ATOM   3887 C  CA     . GLY B 1  217 ? -3.54196  21.96771  -2.24729  1.000 28.24493  ? 247 GLY B CA     1 
ATOM   3888 C  C      . GLY B 1  217 ? -3.90953  23.42085  -1.99229  1.000 32.73728  ? 247 GLY B C      1 
ATOM   3889 O  O      . GLY B 1  217 ? -4.88692  23.93482  -2.54709  1.000 33.31601  ? 247 GLY B O      1 
ATOM   3890 N  N      . LEU B 1  218 ? -3.15194  24.09485  -1.12119  1.000 31.02514  ? 248 LEU B N      1 
ATOM   3891 C  CA     . LEU B 1  218 ? -3.39766  25.52013  -0.86995  1.000 28.95883  ? 248 LEU B CA     1 
ATOM   3892 C  C      . LEU B 1  218 ? -3.25202  26.33865  -2.14944  1.000 30.33730  ? 248 LEU B C      1 
ATOM   3893 O  O      . LEU B 1  218 ? -4.07018  27.22489  -2.43117  1.000 33.87209  ? 248 LEU B O      1 
ATOM   3894 C  CB     . LEU B 1  218 ? -2.43825  26.04844  0.20764   1.000 31.86198  ? 248 LEU B CB     1 
ATOM   3895 C  CG     . LEU B 1  218 ? -2.64132  25.62510  1.66897   1.000 31.56057  ? 248 LEU B CG     1 
ATOM   3896 C  CD1    . LEU B 1  218 ? -1.45535  26.04262  2.53689   1.000 32.17493  ? 248 LEU B CD1    1 
ATOM   3897 C  CD2    . LEU B 1  218 ? -3.91757  26.21355  2.21393   1.000 26.81021  ? 248 LEU B CD2    1 
ATOM   3898 N  N      . CYS B 1  219 ? -2.20472  26.05930  -2.92804  1.000 33.64449  ? 249 CYS B N      1 
ATOM   3899 C  CA     . CYS B 1  219 ? -2.01129  26.76915  -4.19289  1.000 38.92841  ? 249 CYS B CA     1 
ATOM   3900 C  C      . CYS B 1  219 ? -3.17299  26.51928  -5.15590  1.000 39.08339  ? 249 CYS B C      1 
ATOM   3901 O  O      . CYS B 1  219 ? -3.72533  27.45642  -5.74832  1.000 36.40569  ? 249 CYS B O      1 
ATOM   3902 C  CB     . CYS B 1  219 ? -0.68861  26.34369  -4.82840  1.000 35.58014  ? 249 CYS B CB     1 
ATOM   3903 S  SG     . CYS B 1  219 ? 0.75698   26.78148  -3.87562  1.000 37.10502  ? 249 CYS B SG     1 
ATOM   3904 N  N      . LEU B 1  220 ? -3.55360  25.25208  -5.32831  1.000 38.45220  ? 250 LEU B N      1 
ATOM   3905 C  CA     . LEU B 1  220 ? -4.66028  24.91024  -6.22036  1.000 33.81456  ? 250 LEU B CA     1 
ATOM   3906 C  C      . LEU B 1  220 ? -5.94187  25.60731  -5.80063  1.000 37.20663  ? 250 LEU B C      1 
ATOM   3907 O  O      . LEU B 1  220 ? -6.71193  26.08385  -6.64552  1.000 38.47872  ? 250 LEU B O      1 
ATOM   3908 C  CB     . LEU B 1  220 ? -4.88489  23.39640  -6.23325  1.000 29.62470  ? 250 LEU B CB     1 
ATOM   3909 C  CG     . LEU B 1  220 ? -3.75786  22.54239  -6.78939  1.000 35.97125  ? 250 LEU B CG     1 
ATOM   3910 C  CD1    . LEU B 1  220 ? -4.09999  21.06651  -6.57776  1.000 31.13845  ? 250 LEU B CD1    1 
ATOM   3911 C  CD2    . LEU B 1  220 ? -3.53218  22.86467  -8.26732  1.000 34.82931  ? 250 LEU B CD2    1 
ATOM   3912 N  N      . GLU B 1  221 ? -6.20106  25.64845  -4.49514  1.000 34.00899  ? 251 GLU B N      1 
ATOM   3913 C  CA     . GLU B 1  221 ? -7.36896  26.35321  -3.98711  1.000 40.46419  ? 251 GLU B CA     1 
ATOM   3914 C  C      . GLU B 1  221 ? -7.29497  27.84082  -4.31847  1.000 42.01111  ? 251 GLU B C      1 
ATOM   3915 O  O      . GLU B 1  221 ? -8.29417  28.44483  -4.73414  1.000 40.61367  ? 251 GLU B O      1 
ATOM   3916 C  CB     . GLU B 1  221 ? -7.47046  26.12474  -2.48217  1.000 37.24216  ? 251 GLU B CB     1 
ATOM   3917 C  CG     . GLU B 1  221 ? -8.55652  26.87993  -1.78275  1.000 39.44589  ? 251 GLU B CG     1 
ATOM   3918 C  CD     . GLU B 1  221 ? -8.56805  26.56016  -0.31041  1.000 43.95326  ? 251 GLU B CD     1 
ATOM   3919 O  OE1    . GLU B 1  221 ? -7.70165  27.10436  0.40279   1.000 38.81524  ? 251 GLU B OE1    1 
ATOM   3920 O  OE2    . GLU B 1  221 ? -9.41925  25.75394  0.12742   1.000 42.89152  ? 251 GLU B OE2    1 
ATOM   3921 N  N      . ARG B 1  222 ? -6.11767  28.44926  -4.14512  1.000 39.32799  ? 252 ARG B N      1 
ATOM   3922 C  CA     . ARG B 1  222 ? -5.97073  29.85181  -4.52845  1.000 40.78484  ? 252 ARG B CA     1 
ATOM   3923 C  C      . ARG B 1  222 ? -6.23478  30.04934  -6.01768  1.000 47.26090  ? 252 ARG B C      1 
ATOM   3924 O  O      . ARG B 1  222 ? -6.80954  31.07070  -6.41906  1.000 41.65362  ? 252 ARG B O      1 
ATOM   3925 C  CB     . ARG B 1  222 ? -4.57303  30.35969  -4.16945  1.000 43.17850  ? 252 ARG B CB     1 
ATOM   3926 C  CG     . ARG B 1  222 ? -4.25717  31.74047  -4.76451  1.000 46.66757  ? 252 ARG B CG     1 
ATOM   3927 C  CD     . ARG B 1  222 ? -4.75679  32.87320  -3.89760  1.000 43.96592  ? 252 ARG B CD     1 
ATOM   3928 N  NE     . ARG B 1  222 ? -4.51964  32.62263  -2.48302  1.000 48.27225  ? 252 ARG B NE     1 
ATOM   3929 C  CZ     . ARG B 1  222 ? -3.49657  33.13073  -1.80813  1.000 56.24679  ? 252 ARG B CZ     1 
ATOM   3930 N  NH1    . ARG B 1  222 ? -2.58137  33.87666  -2.40614  1.000 49.12412  ? 252 ARG B NH1    1 
ATOM   3931 N  NH2    . ARG B 1  222 ? -3.37308  32.86153  -0.50689  1.000 51.37253  ? 252 ARG B NH2    1 
ATOM   3932 N  N      . LEU B 1  223 ? -5.86230  29.07225  -6.84325  1.000 39.15599  ? 253 LEU B N      1 
ATOM   3933 C  CA     . LEU B 1  223 ? -6.02602  29.16493  -8.28970  1.000 39.30962  ? 253 LEU B CA     1 
ATOM   3934 C  C      . LEU B 1  223 ? -7.42463  28.78559  -8.76390  1.000 42.83559  ? 253 LEU B C      1 
ATOM   3935 O  O      . LEU B 1  223 ? -7.71817  28.92779  -9.95419  1.000 39.15378  ? 253 LEU B O      1 
ATOM   3936 C  CB     . LEU B 1  223 ? -4.98806  28.28918  -8.98676  1.000 40.03171  ? 253 LEU B CB     1 
ATOM   3937 C  CG     . LEU B 1  223 ? -3.55135  28.76062  -8.82047  1.000 34.74267  ? 253 LEU B CG     1 
ATOM   3938 C  CD1    . LEU B 1  223 ? -2.59567  27.67288  -9.26560  1.000 36.64719  ? 253 LEU B CD1    1 
ATOM   3939 C  CD2    . LEU B 1  223 ? -3.31621  30.04748  -9.61524  1.000 40.75177  ? 253 LEU B CD2    1 
ATOM   3940 N  N      . ASN B 1  224 ? -8.30751  28.35441  -7.86935  1.000 38.38024  ? 254 ASN B N      1 
ATOM   3941 C  CA     . ASN B 1  224 ? -9.63795  27.88662  -8.23865  1.000 47.30202  ? 254 ASN B CA     1 
ATOM   3942 C  C      . ASN B 1  224 ? -9.57312  26.63664  -9.11761  1.000 45.48196  ? 254 ASN B C      1 
ATOM   3943 O  O      . ASN B 1  224 ? -10.51242 26.35278  -9.86915  1.000 45.77215  ? 254 ASN B O      1 
ATOM   3944 C  CB     . ASN B 1  224 ? -10.43035 28.98726  -8.96302  1.000 45.59739  ? 254 ASN B CB     1 
ATOM   3945 C  CG     . ASN B 1  224 ? -10.58967 30.25190  -8.12691  1.000 60.60879  ? 254 ASN B CG     1 
ATOM   3946 O  OD1    . ASN B 1  224 ? -10.87586 30.19412  -6.93075  1.000 66.87606  ? 254 ASN B OD1    1 
ATOM   3947 N  ND2    . ASN B 1  224 ? -10.39768 31.40620  -8.76222  1.000 60.99145  ? 254 ASN B ND2    1 
ATOM   3948 N  N      . ILE B 1  225 ? -8.48647  25.87252  -9.03570  1.000 39.63970  ? 255 ILE B N      1 
ATOM   3949 C  CA     . ILE B 1  225 ? -8.38398  24.60089  -9.74767  1.000 44.34457  ? 255 ILE B CA     1 
ATOM   3950 C  C      . ILE B 1  225 ? -8.97857  23.51673  -8.86216  1.000 46.68602  ? 255 ILE B C      1 
ATOM   3951 O  O      . ILE B 1  225 ? -8.44835  23.21896  -7.78733  1.000 43.47118  ? 255 ILE B O      1 
ATOM   3952 C  CB     . ILE B 1  225 ? -6.92679  24.27709  -10.10873 1.000 37.68515  ? 255 ILE B CB     1 
ATOM   3953 C  CG1    . ILE B 1  225 ? -6.39375  25.28049  -11.13307 1.000 39.67069  ? 255 ILE B CG1    1 
ATOM   3954 C  CG2    . ILE B 1  225 ? -6.80139  22.83850  -10.60240 1.000 38.33160  ? 255 ILE B CG2    1 
ATOM   3955 C  CD1    . ILE B 1  225 ? -4.89746  25.23236  -11.32814 1.000 38.64643  ? 255 ILE B CD1    1 
ATOM   3956 N  N      . ARG B 1  226 ? -10.05929 22.90095  -9.31618  1.000 46.05178  ? 256 ARG B N      1 
ATOM   3957 C  CA     . ARG B 1  226 ? -10.71679 21.90076  -8.49903  1.000 45.45361  ? 256 ARG B CA     1 
ATOM   3958 C  C      . ARG B 1  226 ? -10.12338 20.53548  -8.79407  1.000 45.13815  ? 256 ARG B C      1 
ATOM   3959 O  O      . ARG B 1  226 ? -9.77679  20.23221  -9.93754  1.000 42.30670  ? 256 ARG B O      1 
ATOM   3960 C  CB     . ARG B 1  226 ? -12.22954 21.90015  -8.71540  1.000 50.37330  ? 256 ARG B CB     1 
ATOM   3961 C  CG     . ARG B 1  226 ? -12.81290 23.28294  -8.51339  1.000 73.65134  ? 256 ARG B CG     1 
ATOM   3962 C  CD     . ARG B 1  226 ? -12.90691 23.58653  -7.01952  1.000 82.49434  ? 256 ARG B CD     1 
ATOM   3963 N  NE     . ARG B 1  226 ? -13.62864 24.81885  -6.72397  1.000 97.04100  ? 256 ARG B NE     1 
ATOM   3964 C  CZ     . ARG B 1  226 ? -14.14487 25.11557  -5.53795  1.000 104.22741 ? 256 ARG B CZ     1 
ATOM   3965 N  NH1    . ARG B 1  226 ? -14.04087 24.28696  -4.51084  1.000 100.15467 ? 256 ARG B NH1    1 
ATOM   3966 N  NH2    . ARG B 1  226 ? -14.78896 26.26861  -5.37993  1.000 104.61887 ? 256 ARG B NH2    1 
ATOM   3967 N  N      . LEU B 1  227 ? -9.96784  19.73444  -7.74405  1.000 37.82607  ? 257 LEU B N      1 
ATOM   3968 C  CA     . LEU B 1  227 ? -9.46822  18.38035  -7.91750  1.000 35.63206  ? 257 LEU B CA     1 
ATOM   3969 C  C      . LEU B 1  227 ? -10.50384 17.53401  -8.64250  1.000 33.70844  ? 257 LEU B C      1 
ATOM   3970 O  O      . LEU B 1  227 ? -11.70947 17.68368  -8.43271  1.000 35.16408  ? 257 LEU B O      1 
ATOM   3971 C  CB     . LEU B 1  227 ? -9.15501  17.74403  -6.56206  1.000 32.79565  ? 257 LEU B CB     1 
ATOM   3972 C  CG     . LEU B 1  227 ? -8.24386  18.52326  -5.61469  1.000 37.66296  ? 257 LEU B CG     1 
ATOM   3973 C  CD1    . LEU B 1  227 ? -7.95208  17.69877  -4.34692  1.000 33.59846  ? 257 LEU B CD1    1 
ATOM   3974 C  CD2    . LEU B 1  227 ? -6.95834  18.91700  -6.32118  1.000 33.68244  ? 257 LEU B CD2    1 
ATOM   3975 N  N      . GLU B 1  228 ? -10.02402 16.60570  -9.46792  1.000 36.58538  ? 258 GLU B N      1 
ATOM   3976 C  CA     . GLU B 1  228 ? -10.89995 15.65624  -10.14318 1.000 43.15131  ? 258 GLU B CA     1 
ATOM   3977 C  C      . GLU B 1  228 ? -10.33526 14.25106  -10.03875 1.000 29.46604  ? 258 GLU B C      1 
ATOM   3978 O  O      . GLU B 1  228 ? -9.12017  14.05562  -10.06433 1.000 36.63194  ? 258 GLU B O      1 
ATOM   3979 C  CB     . GLU B 1  228 ? -11.06869 15.96772  -11.64043 1.000 36.26927  ? 258 GLU B CB     1 
ATOM   3980 C  CG     . GLU B 1  228 ? -11.57417 17.34201  -11.97743 1.000 44.26497  ? 258 GLU B CG     1 
ATOM   3981 C  CD     . GLU B 1  228 ? -11.55273 17.58632  -13.47422 1.000 54.16274  ? 258 GLU B CD     1 
ATOM   3982 O  OE1    . GLU B 1  228 ? -11.99737 16.68645  -14.22196 1.000 55.38071  ? 258 GLU B OE1    1 
ATOM   3983 O  OE2    . GLU B 1  228 ? -11.06894 18.66159  -13.89994 1.000 54.51703  ? 258 GLU B OE2    1 
ATOM   3984 N  N      . GLU B 1  229 ? -11.24257 13.27791  -9.94624  1.000 39.03506  ? 259 GLU B N      1 
ATOM   3985 C  CA     . GLU B 1  229 ? -10.86132 11.87130  -10.00468 1.000 38.27400  ? 259 GLU B CA     1 
ATOM   3986 C  C      . GLU B 1  229 ? -10.42960 11.51330  -11.42449 1.000 36.64585  ? 259 GLU B C      1 
ATOM   3987 O  O      . GLU B 1  229 ? -10.99148 12.01455  -12.40466 1.000 37.13567  ? 259 GLU B O      1 
ATOM   3988 C  CB     . GLU B 1  229 ? -12.02655 10.97954  -9.57290  1.000 42.87916  ? 259 GLU B CB     1 
ATOM   3989 C  CG     . GLU B 1  229 ? -12.57567 11.27882  -8.18999  1.000 51.20513  ? 259 GLU B CG     1 
ATOM   3990 C  CD     . GLU B 1  229 ? -11.76597 10.62206  -7.08117  1.000 49.59662  ? 259 GLU B CD     1 
ATOM   3991 O  OE1    . GLU B 1  229 ? -10.82217 9.86694   -7.39661  1.000 43.39601  ? 259 GLU B OE1    1 
ATOM   3992 O  OE2    . GLU B 1  229 ? -12.07230 10.87364  -5.89570  1.000 54.46392  ? 259 GLU B OE2    1 
ATOM   3993 N  N      . LEU B 1  230 ? -9.39474  10.67788  -11.53485 1.000 32.64493  ? 260 LEU B N      1 
ATOM   3994 C  CA     . LEU B 1  230 ? -8.89307  10.29383  -12.85142 1.000 39.78573  ? 260 LEU B CA     1 
ATOM   3995 C  C      . LEU B 1  230 ? -9.87664  9.38486   -13.57877 1.000 41.30413  ? 260 LEU B C      1 
ATOM   3996 O  O      . LEU B 1  230 ? -9.98174  9.44389   -14.80777 1.000 38.49971  ? 260 LEU B O      1 
ATOM   3997 C  CB     . LEU B 1  230 ? -7.53503  9.60296   -12.72766 1.000 41.13489  ? 260 LEU B CB     1 
ATOM   3998 C  CG     . LEU B 1  230 ? -6.92997  9.09000   -14.03921 1.000 39.37314  ? 260 LEU B CG     1 
ATOM   3999 C  CD1    . LEU B 1  230 ? -6.70251  10.24792  -14.98185 1.000 41.61859  ? 260 LEU B CD1    1 
ATOM   4000 C  CD2    . LEU B 1  230 ? -5.62099  8.36865   -13.80363 1.000 36.35409  ? 260 LEU B CD2    1 
ATOM   4001 N  N      . HIS B 1  231 ? -10.59952 8.54826   -12.84051 1.000 39.61060  ? 261 HIS B N      1 
ATOM   4002 C  CA     . HIS B 1  231 ? -11.40096 7.49267   -13.43492 1.000 39.69691  ? 261 HIS B CA     1 
ATOM   4003 C  C      . HIS B 1  231 ? -12.57791 7.18226   -12.51735 1.000 44.96861  ? 261 HIS B C      1 
ATOM   4004 O  O      . HIS B 1  231 ? -12.59950 7.58328   -11.35122 1.000 48.89594  ? 261 HIS B O      1 
ATOM   4005 C  CB     . HIS B 1  231 ? -10.51468 6.27139   -13.70358 1.000 46.31721  ? 261 HIS B CB     1 
ATOM   4006 C  CG     . HIS B 1  231 ? -11.22347 5.13711   -14.36720 1.000 50.00032  ? 261 HIS B CG     1 
ATOM   4007 N  ND1    . HIS B 1  231 ? -11.51961 3.96447   -13.70812 1.000 53.28454  ? 261 HIS B ND1    1 
ATOM   4008 C  CD2    . HIS B 1  231 ? -11.70970 4.99953   -15.62281 1.000 48.90912  ? 261 HIS B CD2    1 
ATOM   4009 C  CE1    . HIS B 1  231 ? -12.14581 3.14518   -14.53438 1.000 50.28412  ? 261 HIS B CE1    1 
ATOM   4010 N  NE2    . HIS B 1  231 ? -12.27661 3.75012   -15.70115 1.000 53.18693  ? 261 HIS B NE2    1 
ATOM   4011 N  N      . SER B 1  232 ? -13.57342 6.47307   -13.06426 1.000 47.14324  ? 262 SER B N      1 
ATOM   4012 C  CA     . SER B 1  232 ? -14.74354 6.08110   -12.28460 1.000 47.57178  ? 262 SER B CA     1 
ATOM   4013 C  C      . SER B 1  232 ? -14.39522 5.09348   -11.18049 1.000 48.22649  ? 262 SER B C      1 
ATOM   4014 O  O      . SER B 1  232 ? -15.17398 4.93310   -10.23631 1.000 53.97940  ? 262 SER B O      1 
ATOM   4015 C  CB     . SER B 1  232 ? -15.80419 5.46231   -13.19653 1.000 54.18605  ? 262 SER B CB     1 
ATOM   4016 O  OG     . SER B 1  232 ? -15.24650 4.43622   -14.01032 1.000 55.72026  ? 262 SER B OG     1 
ATOM   4017 N  N      . GLN B 1  233 ? -13.26201 4.42125   -11.28763 1.000 51.91837  ? 263 GLN B N      1 
ATOM   4018 C  CA     . GLN B 1  233 ? -12.78109 3.50749   -10.27035 1.000 51.42608  ? 263 GLN B CA     1 
ATOM   4019 C  C      . GLN B 1  233 ? -11.50379 4.05242   -9.64781  1.000 43.96077  ? 263 GLN B C      1 
ATOM   4020 O  O      . GLN B 1  233 ? -10.76522 4.80996   -10.28598 1.000 41.10364  ? 263 GLN B O      1 
ATOM   4021 C  CB     . GLN B 1  233 ? -12.51802 2.10931   -10.84370 1.000 48.15379  ? 263 GLN B CB     1 
ATOM   4022 C  CG     . GLN B 1  233 ? -13.75682 1.47279   -11.43696 1.000 53.84176  ? 263 GLN B CG     1 
ATOM   4023 C  CD     . GLN B 1  233 ? -14.84168 1.26438   -10.39750 1.000 64.56627  ? 263 GLN B CD     1 
ATOM   4024 O  OE1    . GLN B 1  233 ? -14.61234 0.64995   -9.35365  1.000 63.49455  ? 263 GLN B OE1    1 
ATOM   4025 N  NE2    . GLN B 1  233 ? -16.02403 1.80797   -10.66234 1.000 74.78279  ? 263 GLN B NE2    1 
ATOM   4026 N  N      . PRO B 1  234 ? -11.22220 3.69867   -8.39928  1.000 46.85165  ? 264 PRO B N      1 
ATOM   4027 C  CA     . PRO B 1  234 ? -9.97583  4.15395   -7.77948  1.000 38.06436  ? 264 PRO B CA     1 
ATOM   4028 C  C      . PRO B 1  234 ? -8.76213  3.61850   -8.52633  1.000 37.22762  ? 264 PRO B C      1 
ATOM   4029 O  O      . PRO B 1  234 ? -8.71012  2.45369   -8.93187  1.000 37.24983  ? 264 PRO B O      1 
ATOM   4030 C  CB     . PRO B 1  234 ? -10.06222 3.58606   -6.35757  1.000 43.73579  ? 264 PRO B CB     1 
ATOM   4031 C  CG     . PRO B 1  234 ? -10.99163 2.41187   -6.48163  1.000 48.05583  ? 264 PRO B CG     1 
ATOM   4032 C  CD     . PRO B 1  234 ? -12.01224 2.84339   -7.49636  1.000 47.36993  ? 264 PRO B CD     1 
ATOM   4033 N  N      . THR B 1  235 ? -7.77434  4.48182   -8.69641  1.000 31.68665  ? 265 THR B N      1 
ATOM   4034 C  CA     . THR B 1  235 ? -6.55644  4.11122   -9.38914  1.000 33.48053  ? 265 THR B CA     1 
ATOM   4035 C  C      . THR B 1  235 ? -5.28789  4.48717   -8.63708  1.000 32.82422  ? 265 THR B C      1 
ATOM   4036 O  O      . THR B 1  235 ? -4.20956  4.03945   -9.03940  1.000 31.98459  ? 265 THR B O      1 
ATOM   4037 C  CB     . THR B 1  235 ? -6.52842  4.73789   -10.79618 1.000 38.67619  ? 265 THR B CB     1 
ATOM   4038 O  OG1    . THR B 1  235 ? -6.69879  6.15666   -10.70088 1.000 34.53262  ? 265 THR B OG1    1 
ATOM   4039 C  CG2    . THR B 1  235 ? -7.66947  4.16452   -11.65673 1.000 37.47901  ? 265 THR B CG2    1 
ATOM   4040 N  N      . PHE B 1  236 ? -5.37000  5.30421   -7.58490  1.000 33.12665  ? 266 PHE B N      1 
ATOM   4041 C  CA     . PHE B 1  236 ? -4.22259  5.64054   -6.74928  1.000 32.78849  ? 266 PHE B CA     1 
ATOM   4042 C  C      . PHE B 1  236 ? -4.42340  5.01292   -5.36986  1.000 30.75312  ? 266 PHE B C      1 
ATOM   4043 O  O      . PHE B 1  236 ? -5.51419  5.11454   -4.79404  1.000 29.16512  ? 266 PHE B O      1 
ATOM   4044 C  CB     . PHE B 1  236 ? -4.05699  7.15912   -6.61846  1.000 32.09164  ? 266 PHE B CB     1 
ATOM   4045 C  CG     . PHE B 1  236 ? -3.74810  7.85998   -7.91762  1.000 30.99571  ? 266 PHE B CG     1 
ATOM   4046 C  CD1    . PHE B 1  236 ? -4.76248  8.17994   -8.80977  1.000 34.92787  ? 266 PHE B CD1    1 
ATOM   4047 C  CD2    . PHE B 1  236 ? -2.44468  8.21732   -8.23457  1.000 29.39786  ? 266 PHE B CD2    1 
ATOM   4048 C  CE1    . PHE B 1  236 ? -4.48233  8.83008   -10.00161 1.000 30.57249  ? 266 PHE B CE1    1 
ATOM   4049 C  CE2    . PHE B 1  236 ? -2.15910  8.87739   -9.42606  1.000 35.70120  ? 266 PHE B CE2    1 
ATOM   4050 C  CZ     . PHE B 1  236 ? -3.18228  9.17779   -10.30634 1.000 31.14685  ? 266 PHE B CZ     1 
ATOM   4051 N  N      . PHE B 1  237 ? -3.38447  4.36663   -4.83851  1.000 33.18373  ? 267 PHE B N      1 
ATOM   4052 C  CA     . PHE B 1  237 ? -3.50492  3.59004   -3.59697  1.000 34.19090  ? 267 PHE B CA     1 
ATOM   4053 C  C      . PHE B 1  237 ? -2.36592  3.90445   -2.63559  1.000 35.17606  ? 267 PHE B C      1 
ATOM   4054 O  O      . PHE B 1  237 ? -1.39140  3.13806   -2.51956  1.000 35.41834  ? 267 PHE B O      1 
ATOM   4055 C  CB     . PHE B 1  237 ? -3.59154  2.09371   -3.90832  1.000 33.41994  ? 267 PHE B CB     1 
ATOM   4056 C  CG     . PHE B 1  237 ? -4.80741  1.73853   -4.70342  1.000 30.67880  ? 267 PHE B CG     1 
ATOM   4057 C  CD1    . PHE B 1  237 ? -4.77649  1.75816   -6.09117  1.000 39.51772  ? 267 PHE B CD1    1 
ATOM   4058 C  CD2    . PHE B 1  237 ? -5.99817  1.42423   -4.07119  1.000 32.98752  ? 267 PHE B CD2    1 
ATOM   4059 C  CE1    . PHE B 1  237 ? -5.90646  1.44372   -6.83112  1.000 29.44369  ? 267 PHE B CE1    1 
ATOM   4060 C  CE2    . PHE B 1  237 ? -7.13069  1.10725   -4.80135  1.000 37.25388  ? 267 PHE B CE2    1 
ATOM   4061 C  CZ     . PHE B 1  237 ? -7.09141  1.12706   -6.18612  1.000 30.91250  ? 267 PHE B CZ     1 
ATOM   4062 N  N      . PRO B 1  238 ? -2.45443  5.03711   -1.92940  1.000 33.52520  ? 268 PRO B N      1 
ATOM   4063 C  CA     . PRO B 1  238 ? -1.42799  5.36530   -0.92454  1.000 34.26536  ? 268 PRO B CA     1 
ATOM   4064 C  C      . PRO B 1  238 ? -1.32440  4.33296   0.18669   1.000 34.06419  ? 268 PRO B C      1 
ATOM   4065 O  O      . PRO B 1  238 ? -0.27325  4.24087   0.83206   1.000 37.16539  ? 268 PRO B O      1 
ATOM   4066 C  CB     . PRO B 1  238 ? -1.89527  6.72440   -0.37438  1.000 34.28640  ? 268 PRO B CB     1 
ATOM   4067 C  CG     . PRO B 1  238 ? -2.83990  7.28348   -1.44862  1.000 32.53630  ? 268 PRO B CG     1 
ATOM   4068 C  CD     . PRO B 1  238 ? -3.50711  6.07034   -2.01510  1.000 34.18515  ? 268 PRO B CD     1 
ATOM   4069 N  N      . GLY B 1  239 ? -2.38735  3.58058   0.44432   1.000 36.78668  ? 269 GLY B N      1 
ATOM   4070 C  CA     . GLY B 1  239 ? -2.40727  2.56028   1.47061   1.000 38.19679  ? 269 GLY B CA     1 
ATOM   4071 C  C      . GLY B 1  239 ? -1.83870  1.22586   1.06242   1.000 38.70992  ? 269 GLY B C      1 
ATOM   4072 O  O      . GLY B 1  239 ? -1.72508  0.33522   1.90859   1.000 33.61484  ? 269 GLY B O      1 
ATOM   4073 N  N      . GLY B 1  240 ? -1.47257  1.06201   -0.20896  1.000 41.34625  ? 270 GLY B N      1 
ATOM   4074 C  CA     . GLY B 1  240 ? -0.93274  -0.18453  -0.71102  1.000 35.33672  ? 270 GLY B CA     1 
ATOM   4075 C  C      . GLY B 1  240 ? -2.01260  -1.15154  -1.15735  1.000 37.52081  ? 270 GLY B C      1 
ATOM   4076 O  O      . GLY B 1  240 ? -3.21379  -0.93721  -0.96485  1.000 37.01498  ? 270 GLY B O      1 
ATOM   4077 N  N      . LEU B 1  241 ? -1.56604  -2.25723  -1.76543  1.000 33.59723  ? 271 LEU B N      1 
ATOM   4078 C  CA     . LEU B 1  241 ? -2.49694  -3.20618  -2.36277  1.000 33.96856  ? 271 LEU B CA     1 
ATOM   4079 C  C      . LEU B 1  241 ? -1.94635  -4.61798  -2.31302  1.000 34.16028  ? 271 LEU B C      1 
ATOM   4080 O  O      . LEU B 1  241 ? -0.73436  -4.83384  -2.40573  1.000 37.61907  ? 271 LEU B O      1 
ATOM   4081 C  CB     . LEU B 1  241 ? -2.79643  -2.90513  -3.83248  1.000 38.51612  ? 271 LEU B CB     1 
ATOM   4082 C  CG     . LEU B 1  241 ? -3.77931  -1.83244  -4.23412  1.000 40.57236  ? 271 LEU B CG     1 
ATOM   4083 C  CD1    . LEU B 1  241 ? -3.75649  -1.78462  -5.75271  1.000 36.74030  ? 271 LEU B CD1    1 
ATOM   4084 C  CD2    . LEU B 1  241 ? -5.16927  -2.13966  -3.69139  1.000 40.39074  ? 271 LEU B CD2    1 
ATOM   4085 N  N      . ARG B 1  242 ? -2.86905  -5.57257  -2.21460  1.000 36.04336  ? 272 ARG B N      1 
ATOM   4086 C  CA     . ARG B 1  242 ? -2.55405  -6.98110  -2.41581  1.000 40.55296  ? 272 ARG B CA     1 
ATOM   4087 C  C      . ARG B 1  242 ? -2.25497  -7.21264  -3.89233  1.000 37.44886  ? 272 ARG B C      1 
ATOM   4088 O  O      . ARG B 1  242 ? -3.07825  -6.89170  -4.75339  1.000 34.74102  ? 272 ARG B O      1 
ATOM   4089 C  CB     . ARG B 1  242 ? -3.73660  -7.82962  -1.96175  1.000 41.69655  ? 272 ARG B CB     1 
ATOM   4090 C  CG     . ARG B 1  242 ? -3.52484  -9.33495  -2.02103  1.000 42.89879  ? 272 ARG B CG     1 
ATOM   4091 C  CD     . ARG B 1  242 ? -4.86646  -10.03408 -1.85762  1.000 42.97571  ? 272 ARG B CD     1 
ATOM   4092 N  NE     . ARG B 1  242 ? -4.70955  -11.35994 -1.27632  1.000 57.60452  ? 272 ARG B NE     1 
ATOM   4093 C  CZ     . ARG B 1  242 ? -5.71247  -12.12150 -0.86077  1.000 47.54454  ? 272 ARG B CZ     1 
ATOM   4094 N  NH1    . ARG B 1  242 ? -6.97390  -11.78584 -1.08405  1.000 55.21733  ? 272 ARG B NH1    1 
ATOM   4095 N  NH2    . ARG B 1  242 ? -5.44069  -13.26893 -0.24587  1.000 46.65215  ? 272 ARG B NH2    1 
ATOM   4096 N  N      . PHE B 1  243 ? -1.08025  -7.74664  -4.19568  1.000 37.91541  ? 273 PHE B N      1 
ATOM   4097 C  CA     . PHE B 1  243 ? -0.65840  -7.81761  -5.58505  1.000 38.21309  ? 273 PHE B CA     1 
ATOM   4098 C  C      . PHE B 1  243 ? -1.38524  -8.90992  -6.35171  1.000 45.04341  ? 273 PHE B C      1 
ATOM   4099 O  O      . PHE B 1  243 ? -1.55706  -10.02976 -5.86051  1.000 44.37238  ? 273 PHE B O      1 
ATOM   4100 C  CB     . PHE B 1  243 ? 0.84218   -8.06309  -5.70586  1.000 38.43228  ? 273 PHE B CB     1 
ATOM   4101 C  CG     . PHE B 1  243 ? 1.28070   -8.25756  -7.12146  1.000 39.66281  ? 273 PHE B CG     1 
ATOM   4102 C  CD1    . PHE B 1  243 ? 1.46554   -7.17572  -7.95321  1.000 35.11923  ? 273 PHE B CD1    1 
ATOM   4103 C  CD2    . PHE B 1  243 ? 1.44187   -9.52952  -7.63820  1.000 40.91210  ? 273 PHE B CD2    1 
ATOM   4104 C  CE1    . PHE B 1  243 ? 1.84874   -7.34909  -9.26679  1.000 43.16722  ? 273 PHE B CE1    1 
ATOM   4105 C  CE2    . PHE B 1  243 ? 1.82127   -9.71874  -8.95397  1.000 42.11530  ? 273 PHE B CE2    1 
ATOM   4106 C  CZ     . PHE B 1  243 ? 2.02371   -8.62259  -9.77160  1.000 47.70058  ? 273 PHE B CZ     1 
ATOM   4107 N  N      . SER B 1  244 ? -1.80056  -8.56976  -7.57106  1.000 40.53087  ? 274 SER B N      1 
ATOM   4108 C  CA     . SER B 1  244 ? -2.12065  -9.55531  -8.59221  1.000 38.16780  ? 274 SER B CA     1 
ATOM   4109 C  C      . SER B 1  244 ? -1.87691  -8.91990  -9.95323  1.000 43.91811  ? 274 SER B C      1 
ATOM   4110 O  O      . SER B 1  244 ? -2.00961  -7.70305  -10.12372 1.000 35.82372  ? 274 SER B O      1 
ATOM   4111 C  CB     . SER B 1  244 ? -3.55836  -10.06297 -8.47491  1.000 33.66534  ? 274 SER B CB     1 
ATOM   4112 O  OG     . SER B 1  244 ? -4.48030  -9.08037  -8.90051  1.000 41.88794  ? 274 SER B OG     1 
ATOM   4113 N  N      . VAL B 1  245 ? -1.47995  -9.75344  -10.91462 1.000 44.30588  ? 275 VAL B N      1 
ATOM   4114 C  CA     . VAL B 1  245 ? -1.24465  -9.26673  -12.27227 1.000 40.84274  ? 275 VAL B CA     1 
ATOM   4115 C  C      . VAL B 1  245 ? -2.47500  -8.52628  -12.78737 1.000 39.47977  ? 275 VAL B C      1 
ATOM   4116 O  O      . VAL B 1  245 ? -2.38450  -7.40841  -13.31767 1.000 43.67657  ? 275 VAL B O      1 
ATOM   4117 C  CB     . VAL B 1  245 ? -0.85414  -10.43921 -13.18980 1.000 45.01862  ? 275 VAL B CB     1 
ATOM   4118 C  CG1    . VAL B 1  245 ? -1.10341  -10.08967 -14.64650 1.000 47.67676  ? 275 VAL B CG1    1 
ATOM   4119 C  CG2    . VAL B 1  245 ? 0.59532   -10.80443 -12.96284 1.000 38.44424  ? 275 VAL B CG2    1 
ATOM   4120 N  N      . CYS B 1  246 ? -3.64956  -9.13972  -12.62922 1.000 41.43883  ? 276 CYS B N      1 
ATOM   4121 C  CA     . CYS B 1  246 ? -4.85950  -8.56316  -13.20361 1.000 48.26728  ? 276 CYS B CA     1 
ATOM   4122 C  C      . CYS B 1  246 ? -5.23135  -7.25135  -12.52396 1.000 43.79293  ? 276 CYS B C      1 
ATOM   4123 O  O      . CYS B 1  246 ? -5.66518  -6.30499  -13.19054 1.000 35.37866  ? 276 CYS B O      1 
ATOM   4124 C  CB     . CYS B 1  246 ? -6.01176  -9.56264  -13.11902 1.000 49.10372  ? 276 CYS B CB     1 
ATOM   4125 S  SG     . CYS B 1  246 ? -5.79748  -10.98999 -14.21955 1.000 68.55390  ? 276 CYS B SG     1 
ATOM   4126 N  N      . LEU B 1  247 ? -5.06330  -7.16818  -11.20346 1.000 44.14319  ? 277 LEU B N      1 
ATOM   4127 C  CA     . LEU B 1  247 ? -5.32140  -5.90613  -10.51615 1.000 38.37629  ? 277 LEU B CA     1 
ATOM   4128 C  C      . LEU B 1  247 ? -4.33406  -4.83102  -10.94704 1.000 39.14180  ? 277 LEU B C      1 
ATOM   4129 O  O      . LEU B 1  247 ? -4.72877  -3.70130  -11.26534 1.000 38.79826  ? 277 LEU B O      1 
ATOM   4130 C  CB     . LEU B 1  247 ? -5.27031  -6.10661  -9.00414  1.000 41.14873  ? 277 LEU B CB     1 
ATOM   4131 C  CG     . LEU B 1  247 ? -5.44254  -4.82978  -8.18879  1.000 37.89574  ? 277 LEU B CG     1 
ATOM   4132 C  CD1    . LEU B 1  247 ? -6.80330  -4.19679  -8.47921  1.000 46.23992  ? 277 LEU B CD1    1 
ATOM   4133 C  CD2    . LEU B 1  247 ? -5.27930  -5.12555  -6.70429  1.000 37.97744  ? 277 LEU B CD2    1 
ATOM   4134 N  N      . PHE B 1  248 ? -3.04190  -5.15506  -10.96009 1.000 33.45470  ? 278 PHE B N      1 
ATOM   4135 C  CA     . PHE B 1  248 ? -2.05797  -4.12177  -11.24730 1.000 36.18201  ? 278 PHE B CA     1 
ATOM   4136 C  C      . PHE B 1  248 ? -2.07567  -3.69187  -12.70594 1.000 41.29692  ? 278 PHE B C      1 
ATOM   4137 O  O      . PHE B 1  248 ? -1.47940  -2.65747  -13.03466 1.000 35.85819  ? 278 PHE B O      1 
ATOM   4138 C  CB     . PHE B 1  248 ? -0.65771  -4.57134  -10.82797 1.000 36.42044  ? 278 PHE B CB     1 
ATOM   4139 C  CG     . PHE B 1  248 ? -0.33777  -4.26861  -9.37550  1.000 33.58237  ? 278 PHE B CG     1 
ATOM   4140 C  CD1    . PHE B 1  248 ? -1.26705  -4.53667  -8.38500  1.000 34.92381  ? 278 PHE B CD1    1 
ATOM   4141 C  CD2    . PHE B 1  248 ? 0.87297   -3.70948  -9.01638  1.000 34.64982  ? 278 PHE B CD2    1 
ATOM   4142 C  CE1    . PHE B 1  248 ? -0.99131  -4.25355  -7.05587  1.000 32.89792  ? 278 PHE B CE1    1 
ATOM   4143 C  CE2    . PHE B 1  248 ? 1.15924   -3.42721  -7.68592  1.000 34.93717  ? 278 PHE B CE2    1 
ATOM   4144 C  CZ     . PHE B 1  248 ? 0.22317   -3.70549  -6.70796  1.000 33.98241  ? 278 PHE B CZ     1 
ATOM   4145 N  N      . ARG B 1  249 ? -2.72200  -4.45436  -13.59084 1.000 41.23641  ? 279 ARG B N      1 
ATOM   4146 C  CA     . ARG B 1  249 ? -2.89134  -3.94473  -14.95077 1.000 40.90841  ? 279 ARG B CA     1 
ATOM   4147 C  C      . ARG B 1  249 ? -3.88604  -2.79028  -15.02555 1.000 41.40630  ? 279 ARG B C      1 
ATOM   4148 O  O      . ARG B 1  249 ? -3.87893  -2.04120  -16.00670 1.000 39.13190  ? 279 ARG B O      1 
ATOM   4149 C  CB     . ARG B 1  249 ? -3.36343  -5.05492  -15.88037 1.000 35.12817  ? 279 ARG B CB     1 
ATOM   4150 C  CG     . ARG B 1  249 ? -2.29071  -6.04158  -16.32465 1.000 38.46719  ? 279 ARG B CG     1 
ATOM   4151 C  CD     . ARG B 1  249 ? -2.94361  -7.07138  -17.22631 1.000 51.82998  ? 279 ARG B CD     1 
ATOM   4152 N  NE     . ARG B 1  249 ? -2.03321  -8.11469  -17.67984 1.000 51.52691  ? 279 ARG B NE     1 
ATOM   4153 C  CZ     . ARG B 1  249 ? -2.36441  -9.04854  -18.56298 1.000 61.48743  ? 279 ARG B CZ     1 
ATOM   4154 N  NH1    . ARG B 1  249 ? -3.56862  -9.08199  -19.11647 1.000 58.90615  ? 279 ARG B NH1    1 
ATOM   4155 N  NH2    . ARG B 1  249 ? -1.46277  -9.96210  -18.91128 1.000 56.55224  ? 279 ARG B NH2    1 
ATOM   4156 N  N      . ARG B 1  250 ? -4.74078  -2.62837  -14.02477 1.000 37.70980  ? 280 ARG B N      1 
ATOM   4157 C  CA     . ARG B 1  250 ? -5.79719  -1.62687  -14.05620 1.000 39.71811  ? 280 ARG B CA     1 
ATOM   4158 C  C      . ARG B 1  250 ? -5.71835  -0.68948  -12.84976 1.000 31.52980  ? 280 ARG B C      1 
ATOM   4159 O  O      . ARG B 1  250 ? -6.73270  -0.25143  -12.31180 1.000 32.58695  ? 280 ARG B O      1 
ATOM   4160 C  CB     . ARG B 1  250 ? -7.16726  -2.29130  -14.16679 1.000 41.54195  ? 280 ARG B CB     1 
ATOM   4161 C  CG     . ARG B 1  250 ? -7.49578  -3.24604  -13.05464 1.000 53.40903  ? 280 ARG B CG     1 
ATOM   4162 C  CD     . ARG B 1  250 ? -8.87904  -3.85951  -13.23077 1.000 60.65484  ? 280 ARG B CD     1 
ATOM   4163 N  NE     . ARG B 1  250 ? -9.35491  -4.46177  -11.98988 1.000 70.21366  ? 280 ARG B NE     1 
ATOM   4164 C  CZ     . ARG B 1  250 ? -9.21433  -5.74318  -11.67228 1.000 75.40259  ? 280 ARG B CZ     1 
ATOM   4165 N  NH1    . ARG B 1  250 ? -8.54031  -6.58086  -12.44676 1.000 73.69600  ? 280 ARG B NH1    1 
ATOM   4166 N  NH2    . ARG B 1  250 ? -9.72779  -6.18772  -10.52841 1.000 77.41931  ? 280 ARG B NH2    1 
ATOM   4167 N  N      . ILE B 1  251 ? -4.50022  -0.38267  -12.40844 1.000 32.87042  ? 281 ILE B N      1 
ATOM   4168 C  CA     . ILE B 1  251 ? -4.27621  0.66118   -11.41506 1.000 33.28081  ? 281 ILE B CA     1 
ATOM   4169 C  C      . ILE B 1  251 ? -3.18898  1.58019   -11.94722 1.000 36.73957  ? 281 ILE B C      1 
ATOM   4170 O  O      . ILE B 1  251 ? -2.42281  1.22615   -12.84606 1.000 40.40340  ? 281 ILE B O      1 
ATOM   4171 C  CB     . ILE B 1  251 ? -3.88169  0.10916   -10.02491 1.000 32.98279  ? 281 ILE B CB     1 
ATOM   4172 C  CG1    . ILE B 1  251 ? -2.49356  -0.51659  -10.08627 1.000 38.25064  ? 281 ILE B CG1    1 
ATOM   4173 C  CG2    . ILE B 1  251 ? -4.91034  -0.89859  -9.53457  1.000 31.33519  ? 281 ILE B CG2    1 
ATOM   4174 C  CD1    . ILE B 1  251 ? -1.89554  -0.76328  -8.73611  1.000 35.69490  ? 281 ILE B CD1    1 
ATOM   4175 N  N      . VAL B 1  252 ? -3.11630  2.77393   -11.36976 1.000 32.55534  ? 282 VAL B N      1 
ATOM   4176 C  CA     . VAL B 1  252 ? -2.10685  3.74432   -11.74160 1.000 34.27632  ? 282 VAL B CA     1 
ATOM   4177 C  C      . VAL B 1  252 ? -0.94478  3.75708   -10.75187 1.000 32.63324  ? 282 VAL B C      1 
ATOM   4178 O  O      . VAL B 1  252 ? 0.21812   3.78658   -11.15103 1.000 33.68445  ? 282 VAL B O      1 
ATOM   4179 C  CB     . VAL B 1  252 ? -2.73767  5.14670   -11.88380 1.000 32.28456  ? 282 VAL B CB     1 
ATOM   4180 C  CG1    . VAL B 1  252 ? -1.64243  6.18103   -11.97592 1.000 33.33638  ? 282 VAL B CG1    1 
ATOM   4181 C  CG2    . VAL B 1  252 ? -3.66569  5.19898   -13.11356 1.000 31.24395  ? 282 VAL B CG2    1 
ATOM   4182 N  N      . ALA B 1  253 ? -1.22858  3.75110   -9.45203  1.000 33.69976  ? 283 ALA B N      1 
ATOM   4183 C  CA     . ALA B 1  253 ? -0.15108  3.93892   -8.48744  1.000 36.41162  ? 283 ALA B CA     1 
ATOM   4184 C  C      . ALA B 1  253 ? -0.42301  3.13176   -7.22847  1.000 28.88307  ? 283 ALA B C      1 
ATOM   4185 O  O      . ALA B 1  253 ? -1.53566  3.14812   -6.70333  1.000 31.57707  ? 283 ALA B O      1 
ATOM   4186 C  CB     . ALA B 1  253 ? 0.01422   5.42655   -8.13510  1.000 34.03594  ? 283 ALA B CB     1 
ATOM   4187 N  N      . CYS B 1  254 ? 0.60420   2.45169   -6.73686  1.000 35.84184  ? 284 CYS B N      1 
ATOM   4188 C  CA     . CYS B 1  254 ? 0.49737   1.69138   -5.49705  1.000 33.72682  ? 284 CYS B CA     1 
ATOM   4189 C  C      . CYS B 1  254 ? 1.71672   1.96827   -4.63196  1.000 34.63589  ? 284 CYS B C      1 
ATOM   4190 O  O      . CYS B 1  254 ? 2.85107   1.84477   -5.09753  1.000 33.68910  ? 284 CYS B O      1 
ATOM   4191 C  CB     . CYS B 1  254 ? 0.37471   0.19214   -5.77383  1.000 33.63630  ? 284 CYS B CB     1 
ATOM   4192 S  SG     . CYS B 1  254 ? 0.19243   -0.82070  -4.26715  1.000 35.61687  ? 284 CYS B SG     1 
ATOM   4193 N  N      . HIS B 1  255 ? 1.47033   2.30379   -3.37081  1.000 34.97261  ? 285 HIS B N      1 
ATOM   4194 C  CA     . HIS B 1  255 ? 2.47890   2.72023   -2.40942  1.000 35.85046  ? 285 HIS B CA     1 
ATOM   4195 C  C      . HIS B 1  255 ? 2.95507   1.50640   -1.59496  1.000 34.24430  ? 285 HIS B C      1 
ATOM   4196 O  O      . HIS B 1  255 ? 2.42339   0.39755   -1.71957  1.000 36.49994  ? 285 HIS B O      1 
ATOM   4197 C  CB     . HIS B 1  255 ? 1.87420   3.82058   -1.52751  1.000 37.17612  ? 285 HIS B CB     1 
ATOM   4198 C  CG     . HIS B 1  255 ? 2.84715   4.50118   -0.61698  1.000 38.87372  ? 285 HIS B CG     1 
ATOM   4199 N  ND1    . HIS B 1  255 ? 2.50371   4.91633   0.65040   1.000 40.16031  ? 285 HIS B ND1    1 
ATOM   4200 C  CD2    . HIS B 1  255 ? 4.14275   4.84919   -0.78845  1.000 38.25337  ? 285 HIS B CD2    1 
ATOM   4201 C  CE1    . HIS B 1  255 ? 3.54353   5.49652   1.21876   1.000 34.86687  ? 285 HIS B CE1    1 
ATOM   4202 N  NE2    . HIS B 1  255 ? 4.55314   5.46306   0.36916   1.000 40.66846  ? 285 HIS B NE2    1 
ATOM   4203 N  N      . PHE B 1  256 ? 3.99726   1.72036   -0.78154  1.000 43.74873  ? 286 PHE B N      1 
ATOM   4204 C  CA     . PHE B 1  256 ? 4.52657   0.70462   0.14665   1.000 36.46352  ? 286 PHE B CA     1 
ATOM   4205 C  C      . PHE B 1  256 ? 5.14997   -0.48650  -0.58823  1.000 41.41329  ? 286 PHE B C      1 
ATOM   4206 O  O      . PHE B 1  256 ? 4.94395   -1.64481  -0.21793  1.000 37.25041  ? 286 PHE B O      1 
ATOM   4207 C  CB     . PHE B 1  256 ? 3.44326   0.22956   1.11894   1.000 41.08988  ? 286 PHE B CB     1 
ATOM   4208 C  CG     . PHE B 1  256 ? 2.98598   1.29518   2.07918   1.000 43.25824  ? 286 PHE B CG     1 
ATOM   4209 C  CD1    . PHE B 1  256 ? 3.90524   2.12719   2.70407   1.000 39.26992  ? 286 PHE B CD1    1 
ATOM   4210 C  CD2    . PHE B 1  256 ? 1.63725   1.47515   2.33902   1.000 41.03271  ? 286 PHE B CD2    1 
ATOM   4211 C  CE1    . PHE B 1  256 ? 3.48548   3.11388   3.58205   1.000 42.03367  ? 286 PHE B CE1    1 
ATOM   4212 C  CE2    . PHE B 1  256 ? 1.20573   2.46440   3.20995   1.000 36.88734  ? 286 PHE B CE2    1 
ATOM   4213 C  CZ     . PHE B 1  256 ? 2.13111   3.28286   3.83550   1.000 37.01832  ? 286 PHE B CZ     1 
ATOM   4214 N  N      . ILE B 1  257 ? 5.95465   -0.19880  -1.60461  1.000 38.36546  ? 287 ILE B N      1 
ATOM   4215 C  CA     . ILE B 1  257 ? 6.59072   -1.23283  -2.41453  1.000 40.67804  ? 287 ILE B CA     1 
ATOM   4216 C  C      . ILE B 1  257 ? 8.09901   -1.00921  -2.37163  1.000 43.20621  ? 287 ILE B C      1 
ATOM   4217 O  O      . ILE B 1  257 ? 8.59023   0.00632   -2.87904  1.000 38.21820  ? 287 ILE B O      1 
ATOM   4218 C  CB     . ILE B 1  257 ? 6.05574   -1.22141  -3.85362  1.000 38.64504  ? 287 ILE B CB     1 
ATOM   4219 C  CG1    . ILE B 1  257 ? 4.59965   -1.70380  -3.85903  1.000 40.80138  ? 287 ILE B CG1    1 
ATOM   4220 C  CG2    . ILE B 1  257 ? 6.93106   -2.05127  -4.77186  1.000 36.64945  ? 287 ILE B CG2    1 
ATOM   4221 C  CD1    . ILE B 1  257 ? 3.92483   -1.61750  -5.20361  1.000 44.88898  ? 287 ILE B CD1    1 
ATOM   4222 N  N      . LYS B 1  258 ? 8.83693   -1.94703  -1.75922  1.000 35.44505  ? 288 LYS B N      1 
ATOM   4223 C  CA     . LYS B 1  258 ? 10.29156  -1.84244  -1.66802  1.000 44.01951  ? 288 LYS B CA     1 
ATOM   4224 C  C      . LYS B 1  258 ? 10.94366  -2.28519  -2.97411  1.000 44.28878  ? 288 LYS B C      1 
ATOM   4225 O  O      . LYS B 1  258 ? 10.31764  -2.93844  -3.81066  1.000 45.31045  ? 288 LYS B O      1 
ATOM   4226 C  CB     . LYS B 1  258 ? 10.82380  -2.69160  -0.51169  1.000 44.29195  ? 288 LYS B CB     1 
ATOM   4227 C  CG     . LYS B 1  258 ? 10.94758  -4.17030  -0.85415  1.000 62.94764  ? 288 LYS B CG     1 
ATOM   4228 C  CD     . LYS B 1  258 ? 11.25075  -5.03423  0.36409   1.000 69.25899  ? 288 LYS B CD     1 
ATOM   4229 C  CE     . LYS B 1  258 ? 11.61299  -6.44751  -0.07004  1.000 72.57161  ? 288 LYS B CE     1 
ATOM   4230 N  NZ     . LYS B 1  258 ? 12.35463  -7.18891  0.98533   1.000 77.48637  ? 288 LYS B NZ     1 
ATOM   4231 N  N      . PRO B 1  259 ? 12.23208  -1.97573  -3.16146  1.000 49.93126  ? 289 PRO B N      1 
ATOM   4232 C  CA     . PRO B 1  259 ? 12.87239  -2.25992  -4.46246  1.000 52.79936  ? 289 PRO B CA     1 
ATOM   4233 C  C      . PRO B 1  259 ? 12.76168  -3.70736  -4.92746  1.000 49.52393  ? 289 PRO B C      1 
ATOM   4234 O  O      . PRO B 1  259 ? 12.33354  -3.95857  -6.06148  1.000 48.44920  ? 289 PRO B O      1 
ATOM   4235 C  CB     . PRO B 1  259 ? 14.32627  -1.84085  -4.21037  1.000 52.43812  ? 289 PRO B CB     1 
ATOM   4236 C  CG     . PRO B 1  259 ? 14.20630  -0.75068  -3.17718  1.000 56.01978  ? 289 PRO B CG     1 
ATOM   4237 C  CD     . PRO B 1  259 ? 13.14644  -1.26942  -2.24478  1.000 50.60830  ? 289 PRO B CD     1 
ATOM   4238 N  N      . ARG B 1  260 ? 13.14854  -4.67028  -4.09032  1.000 52.05219  ? 290 ARG B N      1 
ATOM   4239 C  CA     . ARG B 1  260 ? 13.05088  -6.07160  -4.48692  1.000 51.91823  ? 290 ARG B CA     1 
ATOM   4240 C  C      . ARG B 1  260 ? 11.62905  -6.41779  -4.90584  1.000 42.63490  ? 290 ARG B C      1 
ATOM   4241 O  O      . ARG B 1  260 ? 11.41063  -7.06803  -5.93697  1.000 45.79137  ? 290 ARG B O      1 
ATOM   4242 C  CB     . ARG B 1  260 ? 13.51041  -6.96817  -3.33799  1.000 57.87009  ? 290 ARG B CB     1 
ATOM   4243 C  CG     . ARG B 1  260 ? 13.17667  -8.45567  -3.49007  1.000 64.61337  ? 290 ARG B CG     1 
ATOM   4244 C  CD     . ARG B 1  260 ? 14.15937  -9.19436  -4.40156  1.000 66.00758  ? 290 ARG B CD     1 
ATOM   4245 N  NE     . ARG B 1  260 ? 13.73529  -9.22981  -5.79596  1.000 64.83926  ? 290 ARG B NE     1 
ATOM   4246 C  CZ     . ARG B 1  260 ? 14.49135  -8.85674  -6.82107  1.000 68.97161  ? 290 ARG B CZ     1 
ATOM   4247 N  NH1    . ARG B 1  260 ? 15.65805  -8.25527  -6.63851  1.000 67.03286  ? 290 ARG B NH1    1 
ATOM   4248 N  NH2    . ARG B 1  260 ? 14.05296  -9.06531  -8.06169  1.000 65.72351  ? 290 ARG B NH2    1 
ATOM   4249 N  N      . THR B 1  261 ? 10.64631  -5.97414  -4.11908  1.000 42.37564  ? 291 THR B N      1 
ATOM   4250 C  CA     . THR B 1  261 ? 9.25355   -6.24382  -4.44685  1.000 38.17040  ? 291 THR B CA     1 
ATOM   4251 C  C      . THR B 1  261 ? 8.87766   -5.64002  -5.79052  1.000 47.55282  ? 291 THR B C      1 
ATOM   4252 O  O      . THR B 1  261 ? 8.17123   -6.27211  -6.58324  1.000 38.48860  ? 291 THR B O      1 
ATOM   4253 C  CB     . THR B 1  261 ? 8.33470   -5.69833  -3.35597  1.000 40.61562  ? 291 THR B CB     1 
ATOM   4254 O  OG1    . THR B 1  261 ? 8.72638   -6.23221  -2.08692  1.000 42.51070  ? 291 THR B OG1    1 
ATOM   4255 C  CG2    . THR B 1  261 ? 6.89816   -6.08963  -3.63539  1.000 43.53749  ? 291 THR B CG2    1 
ATOM   4256 N  N      . LEU B 1  262 ? 9.30572   -4.40083  -6.04161  1.000 41.63437  ? 292 LEU B N      1 
ATOM   4257 C  CA     . LEU B 1  262 ? 9.01432   -3.74847  -7.31082  1.000 42.64990  ? 292 LEU B CA     1 
ATOM   4258 C  C      . LEU B 1  262 ? 9.58963   -4.53928  -8.47221  1.000 42.49048  ? 292 LEU B C      1 
ATOM   4259 O  O      . LEU B 1  262 ? 8.93191   -4.71035  -9.50278  1.000 45.48889  ? 292 LEU B O      1 
ATOM   4260 C  CB     . LEU B 1  262 ? 9.56991   -2.32036  -7.30601  1.000 40.78684  ? 292 LEU B CB     1 
ATOM   4261 C  CG     . LEU B 1  262 ? 9.43074   -1.52836  -8.60976  1.000 44.22056  ? 292 LEU B CG     1 
ATOM   4262 C  CD1    . LEU B 1  262 ? 7.97843   -1.46566  -9.04691  1.000 37.15306  ? 292 LEU B CD1    1 
ATOM   4263 C  CD2    . LEU B 1  262 ? 9.98673   -0.11534  -8.45430  1.000 45.52286  ? 292 LEU B CD2    1 
ATOM   4264 N  N      . LEU B 1  263 ? 10.83494  -4.99950  -8.34092  1.000 44.92629  ? 293 LEU B N      1 
ATOM   4265 C  CA     . LEU B 1  263 ? 11.42800  -5.78265  -9.41839  1.000 48.71208  ? 293 LEU B CA     1 
ATOM   4266 C  C      . LEU B 1  263 ? 10.63675  -7.06432  -9.65291  1.000 47.64691  ? 293 LEU B C      1 
ATOM   4267 O  O      . LEU B 1  263 ? 10.40697  -7.46346  -10.80211 1.000 45.34405  ? 293 LEU B O      1 
ATOM   4268 C  CB     . LEU B 1  263 ? 12.89266  -6.07952  -9.10318  1.000 53.28260  ? 293 LEU B CB     1 
ATOM   4269 C  CG     . LEU B 1  263 ? 13.75590  -4.81360  -9.06080  1.000 48.92900  ? 293 LEU B CG     1 
ATOM   4270 C  CD1    . LEU B 1  263 ? 15.09533  -5.08163  -8.39779  1.000 64.37238  ? 293 LEU B CD1    1 
ATOM   4271 C  CD2    . LEU B 1  263 ? 13.94786  -4.23727  -10.45349 1.000 54.14392  ? 293 LEU B CD2    1 
ATOM   4272 N  N      . ASP B 1  264 ? 10.19279  -7.71004  -8.57403  1.000 42.12867  ? 294 ASP B N      1 
ATOM   4273 C  CA     . ASP B 1  264 ? 9.37687   -8.91597  -8.71926  1.000 48.00119  ? 294 ASP B CA     1 
ATOM   4274 C  C      . ASP B 1  264 ? 8.03262   -8.62231  -9.38267  1.000 47.52177  ? 294 ASP B C      1 
ATOM   4275 O  O      . ASP B 1  264 ? 7.56292   -9.41053  -10.21056 1.000 41.37168  ? 294 ASP B O      1 
ATOM   4276 C  CB     . ASP B 1  264 ? 9.16925   -9.58079  -7.36219  1.000 42.15459  ? 294 ASP B CB     1 
ATOM   4277 C  CG     . ASP B 1  264 ? 10.43544  -10.21729 -6.82772  1.000 46.10183  ? 294 ASP B CG     1 
ATOM   4278 O  OD1    . ASP B 1  264 ? 11.35411  -10.49032 -7.62779  1.000 46.52582  ? 294 ASP B OD1    1 
ATOM   4279 O  OD2    . ASP B 1  264 ? 10.52019  -10.42156 -5.59927  1.000 48.04034  ? 294 ASP B OD2    1 
ATOM   4280 N  N      . TYR B 1  265 ? 7.37785   -7.51862  -9.00659  1.000 44.18292  ? 295 TYR B N      1 
ATOM   4281 C  CA     . TYR B 1  265 ? 6.09882   -7.17188  -9.62578  1.000 43.53131  ? 295 TYR B CA     1 
ATOM   4282 C  C      . TYR B 1  265 ? 6.28278   -6.87464  -11.10873 1.000 48.11155  ? 295 TYR B C      1 
ATOM   4283 O  O      . TYR B 1  265 ? 5.47660   -7.30081  -11.94835 1.000 41.61154  ? 295 TYR B O      1 
ATOM   4284 C  CB     . TYR B 1  265 ? 5.46457   -5.96316  -8.92974  1.000 43.87559  ? 295 TYR B CB     1 
ATOM   4285 C  CG     . TYR B 1  265 ? 4.86033   -6.20887  -7.56452  1.000 42.56812  ? 295 TYR B CG     1 
ATOM   4286 C  CD1    . TYR B 1  265 ? 4.89011   -7.46537  -6.97075  1.000 44.19993  ? 295 TYR B CD1    1 
ATOM   4287 C  CD2    . TYR B 1  265 ? 4.25230   -5.16865  -6.86427  1.000 45.69529  ? 295 TYR B CD2    1 
ATOM   4288 C  CE1    . TYR B 1  265 ? 4.32358   -7.67526  -5.71845  1.000 43.52459  ? 295 TYR B CE1    1 
ATOM   4289 C  CE2    . TYR B 1  265 ? 3.69098   -5.36626  -5.61420  1.000 40.02884  ? 295 TYR B CE2    1 
ATOM   4290 C  CZ     . TYR B 1  265 ? 3.72864   -6.62203  -5.04473  1.000 44.24089  ? 295 TYR B CZ     1 
ATOM   4291 O  OH     . TYR B 1  265 ? 3.16653   -6.82082  -3.80242  1.000 43.76596  ? 295 TYR B OH     1 
ATOM   4292 N  N      . TRP B 1  266 ? 7.34066   -6.13809  -11.44912 1.000 45.55796  ? 296 TRP B N      1 
ATOM   4293 C  CA     . TRP B 1  266 ? 7.60184   -5.83759  -12.84817 1.000 48.46570  ? 296 TRP B CA     1 
ATOM   4294 C  C      . TRP B 1  266 ? 7.83001   -7.12031  -13.63249 1.000 48.73204  ? 296 TRP B C      1 
ATOM   4295 O  O      . TRP B 1  266 ? 7.25884   -7.31550  -14.71424 1.000 47.08139  ? 296 TRP B O      1 
ATOM   4296 C  CB     . TRP B 1  266 ? 8.80776   -4.91073  -12.95978 1.000 42.34855  ? 296 TRP B CB     1 
ATOM   4297 C  CG     . TRP B 1  266 ? 8.85575   -4.19089  -14.25488 1.000 48.86612  ? 296 TRP B CG     1 
ATOM   4298 C  CD1    . TRP B 1  266 ? 9.69857   -4.43432  -15.29787 1.000 55.84071  ? 296 TRP B CD1    1 
ATOM   4299 C  CD2    . TRP B 1  266 ? 8.01290   -3.10469  -14.66279 1.000 52.01562  ? 296 TRP B CD2    1 
ATOM   4300 N  NE1    . TRP B 1  266 ? 9.43318   -3.56552  -16.33405 1.000 52.14007  ? 296 TRP B NE1    1 
ATOM   4301 C  CE2    . TRP B 1  266 ? 8.40557   -2.73746  -15.96693 1.000 52.57727  ? 296 TRP B CE2    1 
ATOM   4302 C  CE3    . TRP B 1  266 ? 6.96486   -2.40738  -14.05310 1.000 48.88832  ? 296 TRP B CE3    1 
ATOM   4303 C  CZ2    . TRP B 1  266 ? 7.79048   -1.69869  -16.66942 1.000 45.66009  ? 296 TRP B CZ2    1 
ATOM   4304 C  CZ3    . TRP B 1  266 ? 6.35453   -1.37612  -14.75549 1.000 49.17208  ? 296 TRP B CZ3    1 
ATOM   4305 C  CH2    . TRP B 1  266 ? 6.76727   -1.03671  -16.04898 1.000 45.24597  ? 296 TRP B CH2    1 
ATOM   4306 N  N      . GLN B 1  267 ? 8.64452   -8.02393  -13.07846 1.000 46.23270  ? 297 GLN B N      1 
ATOM   4307 C  CA     . GLN B 1  267 ? 8.86440   -9.31540  -13.71482 1.000 47.58451  ? 297 GLN B CA     1 
ATOM   4308 C  C      . GLN B 1  267 ? 7.55984   -10.08968 -13.85606 1.000 46.11529  ? 297 GLN B C      1 
ATOM   4309 O  O      . GLN B 1  267 ? 7.31236   -10.71547 -14.88937 1.000 50.18351  ? 297 GLN B O      1 
ATOM   4310 C  CB     . GLN B 1  267 ? 9.88884   -10.11688 -12.91272 1.000 51.50709  ? 297 GLN B CB     1 
ATOM   4311 C  CG     . GLN B 1  267 ? 10.40167  -11.36063 -13.61947 1.000 58.72277  ? 297 GLN B CG     1 
ATOM   4312 C  CD     . GLN B 1  267 ? 11.07604  -11.03934 -14.94566 1.000 65.01561  ? 297 GLN B CD     1 
ATOM   4313 O  OE1    . GLN B 1  267 ? 12.12359  -10.38673 -14.98574 1.000 68.90099  ? 297 GLN B OE1    1 
ATOM   4314 N  NE2    . GLN B 1  267 ? 10.47890  -11.50472 -16.03938 1.000 57.93233  ? 297 GLN B NE2    1 
ATOM   4315 N  N      . ALA B 1  268 ? 6.71614   -10.07006 -12.82448 1.000 42.88907  ? 298 ALA B N      1 
ATOM   4316 C  CA     . ALA B 1  268 ? 5.43057   -10.75476 -12.90029 1.000 40.79077  ? 298 ALA B CA     1 
ATOM   4317 C  C      . ALA B 1  268 ? 4.61692   -10.24291 -14.07736 1.000 46.95637  ? 298 ALA B C      1 
ATOM   4318 O  O      . ALA B 1  268 ? 4.04053   -11.02528 -14.84194 1.000 44.41143  ? 298 ALA B O      1 
ATOM   4319 C  CB     . ALA B 1  268 ? 4.66014   -10.56596 -11.59557 1.000 40.03067  ? 298 ALA B CB     1 
ATOM   4320 N  N      . LEU B 1  269 ? 4.56285   -8.92026  -14.23653 1.000 40.94113  ? 299 LEU B N      1 
ATOM   4321 C  CA     . LEU B 1  269 ? 3.79400   -8.32985  -15.32994 1.000 42.09163  ? 299 LEU B CA     1 
ATOM   4322 C  C      . LEU B 1  269 ? 4.39320   -8.68376  -16.68639 1.000 45.17111  ? 299 LEU B C      1 
ATOM   4323 O  O      . LEU B 1  269 ? 3.66028   -8.93767  -17.65037 1.000 43.83151  ? 299 LEU B O      1 
ATOM   4324 C  CB     . LEU B 1  269 ? 3.71547   -6.81389  -15.13475 1.000 40.16417  ? 299 LEU B CB     1 
ATOM   4325 C  CG     . LEU B 1  269 ? 2.87358   -6.43022  -13.91987 1.000 38.98277  ? 299 LEU B CG     1 
ATOM   4326 C  CD1    . LEU B 1  269 ? 3.25451   -5.04562  -13.38729 1.000 45.51295  ? 299 LEU B CD1    1 
ATOM   4327 C  CD2    . LEU B 1  269 ? 1.39499   -6.47421  -14.30147 1.000 39.81798  ? 299 LEU B CD2    1 
ATOM   4328 N  N      . GLU B 1  270 ? 5.72130   -8.72347  -16.77870 1.000 46.64690  ? 300 GLU B N      1 
ATOM   4329 C  CA     . GLU B 1  270 ? 6.34560   -9.14173  -18.02825 1.000 53.37658  ? 300 GLU B CA     1 
ATOM   4330 C  C      . GLU B 1  270 ? 5.99528   -10.59628 -18.34729 1.000 58.30576  ? 300 GLU B C      1 
ATOM   4331 O  O      . GLU B 1  270 ? 5.53294   -10.91082 -19.45041 1.000 60.70323  ? 300 GLU B O      1 
ATOM   4332 C  CB     . GLU B 1  270 ? 7.86182   -8.96197  -17.94177 1.000 55.20997  ? 300 GLU B CB     1 
ATOM   4333 C  CG     . GLU B 1  270 ? 8.36192   -7.51674  -17.99321 1.000 62.02770  ? 300 GLU B CG     1 
ATOM   4334 C  CD     . GLU B 1  270 ? 8.04640   -6.78876  -19.29404 1.000 71.66803  ? 300 GLU B CD     1 
ATOM   4335 O  OE1    . GLU B 1  270 ? 7.86008   -7.45575  -20.33585 1.000 77.25927  ? 300 GLU B OE1    1 
ATOM   4336 O  OE2    . GLU B 1  270 ? 8.00401   -5.53730  -19.27039 1.000 67.55101  ? 300 GLU B OE2    1 
ATOM   4337 N  N      . ASN B 1  271 ? 6.16803   -11.49122 -17.36688 1.000 51.28255  ? 301 ASN B N      1 
ATOM   4338 C  CA     . ASN B 1  271 ? 5.95637   -12.92262 -17.57539 1.000 50.15875  ? 301 ASN B CA     1 
ATOM   4339 C  C      . ASN B 1  271 ? 4.52714   -13.23324 -17.99188 1.000 48.98303  ? 301 ASN B C      1 
ATOM   4340 O  O      . ASN B 1  271 ? 4.28661   -14.21241 -18.70637 1.000 57.27515  ? 301 ASN B O      1 
ATOM   4341 C  CB     . ASN B 1  271 ? 6.29576   -13.70625 -16.29897 1.000 45.71525  ? 301 ASN B CB     1 
ATOM   4342 C  CG     . ASN B 1  271 ? 7.76597   -13.66372 -15.95619 1.000 49.56664  ? 301 ASN B CG     1 
ATOM   4343 O  OD1    . ASN B 1  271 ? 8.59259   -13.23816 -16.76063 1.000 56.50027  ? 301 ASN B OD1    1 
ATOM   4344 N  ND2    . ASN B 1  271 ? 8.10517   -14.11780 -14.74837 1.000 52.07502  ? 301 ASN B ND2    1 
ATOM   4345 N  N      . SER B 1  272 ? 3.56664   -12.44707 -17.52447 1.000 51.42232  ? 302 SER B N      1 
ATOM   4346 C  CA     . SER B 1  272 ? 2.15752   -12.68117 -17.80076 1.000 51.57506  ? 302 SER B CA     1 
ATOM   4347 C  C      . SER B 1  272 ? 1.64157   -11.80727 -18.93337 1.000 50.76672  ? 302 SER B C      1 
ATOM   4348 O  O      . SER B 1  272 ? 0.44425   -11.84328 -19.23698 1.000 47.51851  ? 302 SER B O      1 
ATOM   4349 C  CB     . SER B 1  272 ? 1.33391   -12.43918 -16.53647 1.000 47.50149  ? 302 SER B CB     1 
ATOM   4350 O  OG     . SER B 1  272 ? 1.64766   -11.16631 -15.99539 1.000 47.79943  ? 302 SER B OG     1 
ATOM   4351 N  N      . ARG B 1  273 ? 2.51358   -11.00995 -19.54279 1.000 50.55515  ? 303 ARG B N      1 
ATOM   4352 C  CA     . ARG B 1  273 ? 2.13485   -10.22868 -20.70762 1.000 60.01430  ? 303 ARG B CA     1 
ATOM   4353 C  C      . ARG B 1  273 ? 1.56880   -11.18234 -21.75220 1.000 67.30487  ? 303 ARG B C      1 
ATOM   4354 O  O      . ARG B 1  273 ? 2.20334   -12.18159 -22.09767 1.000 72.89473  ? 303 ARG B O      1 
ATOM   4355 C  CB     . ARG B 1  273 ? 3.36869   -9.49933  -21.24274 1.000 63.45425  ? 303 ARG B CB     1 
ATOM   4356 C  CG     . ARG B 1  273 ? 3.11667   -8.40421  -22.26019 1.000 82.03673  ? 303 ARG B CG     1 
ATOM   4357 C  CD     . ARG B 1  273 ? 4.43018   -7.94094  -22.88124 1.000 85.63729  ? 303 ARG B CD     1 
ATOM   4358 N  NE     . ARG B 1  273 ? 5.29131   -9.08145  -23.17087 1.000 92.11683  ? 303 ARG B NE     1 
ATOM   4359 C  CZ     . ARG B 1  273 ? 5.19177   -9.80658  -24.27818 1.000 100.40408 ? 303 ARG B CZ     1 
ATOM   4360 N  NH1    . ARG B 1  273 ? 4.36017   -9.46752  -25.25209 1.000 101.68294 ? 303 ARG B NH1    1 
ATOM   4361 N  NH2    . ARG B 1  273 ? 5.95363   -10.88829 -24.41989 1.000 98.81517  ? 303 ARG B NH2    1 
ATOM   4362 N  N      . GLY B 1  274 ? 0.36643   -10.90590 -22.24185 1.000 67.17607  ? 304 GLY B N      1 
ATOM   4363 C  CA     . GLY B 1  274 ? -0.24174  -11.79479 -23.20908 1.000 68.30851  ? 304 GLY B CA     1 
ATOM   4364 C  C      . GLY B 1  274 ? -1.24499  -12.78293 -22.64706 1.000 66.69415  ? 304 GLY B C      1 
ATOM   4365 O  O      . GLY B 1  274 ? -1.86557  -13.51565 -23.42861 1.000 66.57539  ? 304 GLY B O      1 
ATOM   4366 N  N      . GLU B 1  275 ? -1.39817  -12.85384 -21.32913 1.000 60.63054  ? 305 GLU B N      1 
ATOM   4367 C  CA     . GLU B 1  275 ? -2.47620  -13.61237 -20.71254 1.000 58.94549  ? 305 GLU B CA     1 
ATOM   4368 C  C      . GLU B 1  275 ? -3.69225  -12.69940 -20.58348 1.000 64.51502  ? 305 GLU B C      1 
ATOM   4369 O  O      . GLU B 1  275 ? -3.57212  -11.47517 -20.63547 1.000 61.89028  ? 305 GLU B O      1 
ATOM   4370 C  CB     . GLU B 1  275 ? -2.04946  -14.12620 -19.33584 1.000 61.32901  ? 305 GLU B CB     1 
ATOM   4371 C  CG     . GLU B 1  275 ? -0.65573  -14.76357 -19.30595 1.000 58.40647  ? 305 GLU B CG     1 
ATOM   4372 C  CD     . GLU B 1  275 ? -0.66711  -16.27653 -19.39527 1.000 65.87764  ? 305 GLU B CD     1 
ATOM   4373 O  OE1    . GLU B 1  275 ? -1.45076  -16.91031 -18.65653 1.000 66.11119  ? 305 GLU B OE1    1 
ATOM   4374 O  OE2    . GLU B 1  275 ? 0.12364   -16.83224 -20.19207 1.000 66.82036  ? 305 GLU B OE2    1 
ATOM   4375 N  N      . ASP B 1  276 ? -4.87032  -13.29275 -20.41386 1.000 70.37459  ? 306 ASP B N      1 
ATOM   4376 C  CA     . ASP B 1  276 ? -6.07726  -12.48722 -20.27695 1.000 76.34486  ? 306 ASP B CA     1 
ATOM   4377 C  C      . ASP B 1  276 ? -6.52287  -12.38265 -18.81994 1.000 79.22825  ? 306 ASP B C      1 
ATOM   4378 O  O      . ASP B 1  276 ? -6.06765  -13.11804 -17.93931 1.000 80.54203  ? 306 ASP B O      1 
ATOM   4379 C  CB     . ASP B 1  276 ? -7.22603  -13.04482 -21.12650 1.000 84.91608  ? 306 ASP B CB     1 
ATOM   4380 C  CG     . ASP B 1  276 ? -6.90149  -13.07948 -22.60643 1.000 94.74045  ? 306 ASP B CG     1 
ATOM   4381 O  OD1    . ASP B 1  276 ? -5.96814  -12.36596 -23.03372 1.000 92.80627  ? 306 ASP B OD1    1 
ATOM   4382 O  OD2    . ASP B 1  276 ? -7.62262  -13.77923 -23.35179 1.000 101.73583 ? 306 ASP B OD2    1 
ATOM   4383 N  N      . CYS B 1  277 ? -7.47005  -11.46534 -18.59034 1.000 77.56354  ? 307 CYS B N      1 
ATOM   4384 C  CA     . CYS B 1  277 ? -7.96275  -11.07603 -17.28002 1.000 76.73138  ? 307 CYS B CA     1 
ATOM   4385 C  C      . CYS B 1  277 ? -9.43590  -10.73790 -17.46286 1.000 76.33016  ? 307 CYS B C      1 
ATOM   4386 O  O      . CYS B 1  277 ? -9.79589  -10.14035 -18.48785 1.000 77.43958  ? 307 CYS B O      1 
ATOM   4387 C  CB     . CYS B 1  277 ? -7.20874  -9.85753  -16.72458 1.000 73.89981  ? 307 CYS B CB     1 
ATOM   4388 S  SG     . CYS B 1  277 ? -5.52499  -10.16549 -16.07255 1.000 62.48136  ? 307 CYS B SG     1 
ATOM   4389 N  N      . PRO B 1  278 ? -10.30818 -11.08367 -16.49891 1.000 76.08044  ? 308 PRO B N      1 
ATOM   4390 C  CA     . PRO B 1  278 ? -11.76242 -10.90526 -16.65716 1.000 69.65715  ? 308 PRO B CA     1 
ATOM   4391 C  C      . PRO B 1  278 ? -12.17947 -9.44609  -16.84211 1.000 80.44561  ? 308 PRO B C      1 
ATOM   4392 O  O      . PRO B 1  278 ? -13.36645 -9.13442  -16.71659 1.000 82.15248  ? 308 PRO B O      1 
ATOM   4393 C  CB     . PRO B 1  278 ? -12.33467 -11.45935 -15.34479 1.000 72.09754  ? 308 PRO B CB     1 
ATOM   4394 C  CG     . PRO B 1  278 ? -11.24917 -12.33616 -14.78520 1.000 76.01429  ? 308 PRO B CG     1 
ATOM   4395 C  CD     . PRO B 1  278 ? -9.96099  -11.70960 -15.21130 1.000 75.25642  ? 308 PRO B CD     1 
HETATM 4396 C  C2     . BGC C 2  .   ? 32.95410  -2.74482  43.69234  1.000 94.83449  ? 1   BGC C C2     1 
HETATM 4397 C  C3     . BGC C 2  .   ? 32.01055  -1.95185  44.58356  1.000 92.05983  ? 1   BGC C C3     1 
HETATM 4398 C  C4     . BGC C 2  .   ? 30.70102  -1.65340  43.85737  1.000 86.73660  ? 1   BGC C C4     1 
HETATM 4399 C  C5     . BGC C 2  .   ? 30.09653  -2.92698  43.26349  1.000 88.80986  ? 1   BGC C C5     1 
HETATM 4400 C  C6     . BGC C 2  .   ? 28.91248  -2.64842  42.36495  1.000 87.69377  ? 1   BGC C C6     1 
HETATM 4401 C  C1     . BGC C 2  .   ? 32.25455  -3.98804  43.15736  1.000 96.41267  ? 1   BGC C C1     1 
HETATM 4402 O  O1     . BGC C 2  .   ? 33.11607  -4.66581  42.29833  1.000 105.75787 ? 1   BGC C O1     1 
HETATM 4403 O  O2     . BGC C 2  .   ? 34.11828  -3.11895  44.42164  1.000 95.84208  ? 1   BGC C O2     1 
HETATM 4404 O  O3     . BGC C 2  .   ? 32.63514  -0.74037  44.99783  1.000 87.10576  ? 1   BGC C O3     1 
HETATM 4405 O  O4     . BGC C 2  .   ? 29.76285  -1.03151  44.73249  1.000 72.44671  ? 1   BGC C O4     1 
HETATM 4406 O  O5     . BGC C 2  .   ? 31.06952  -3.60788  42.45277  1.000 93.20875  ? 1   BGC C O5     1 
HETATM 4407 O  O6     . BGC C 2  .   ? 29.31843  -2.43698  41.01767  1.000 84.15631  ? 1   BGC C O6     1 
HETATM 4408 C  C1     . GAL C 2  .   ? 29.40218  -1.79836  45.90900  1.000 68.02290  ? 2   GAL C C1     1 
HETATM 4409 C  C2     . GAL C 2  .   ? 29.53154  -0.84229  47.11247  1.000 65.91003  ? 2   GAL C C2     1 
HETATM 4410 C  C3     . GAL C 2  .   ? 29.04637  -1.45175  48.41004  1.000 63.74734  ? 2   GAL C C3     1 
HETATM 4411 C  C4     . GAL C 2  .   ? 27.58778  -1.78110  48.23310  1.000 57.02993  ? 2   GAL C C4     1 
HETATM 4412 C  C5     . GAL C 2  .   ? 27.41736  -2.74802  47.03617  1.000 60.15578  ? 2   GAL C C5     1 
HETATM 4413 C  C6     . GAL C 2  .   ? 25.91720  -3.02205  46.66285  1.000 64.80930  ? 2   GAL C C6     1 
HETATM 4414 O  O2     . GAL C 2  .   ? 30.88027  -0.41970  47.30827  1.000 75.01533  ? 2   GAL C O2     1 
HETATM 4415 O  O3     . GAL C 2  .   ? 29.15102  -0.50556  49.49652  1.000 62.12788  ? 2   GAL C O3     1 
HETATM 4416 O  O4     . GAL C 2  .   ? 26.85574  -0.56868  47.92881  1.000 38.23095  ? 2   GAL C O4     1 
HETATM 4417 O  O5     . GAL C 2  .   ? 28.08232  -2.35967  45.79902  1.000 71.39256  ? 2   GAL C O5     1 
HETATM 4418 O  O6     . GAL C 2  .   ? 25.57768  -2.55663  45.36014  1.000 71.59631  ? 2   GAL C O6     1 
HETATM 4419 H  H1     . GAL C 2  .   ? 30.09346  -2.64172  46.06088  1.000 81.65513  ? 2   GAL C H1     1 
HETATM 4420 H  H2     . GAL C 2  .   ? 28.85256  -0.00016  46.90223  1.000 79.11970  ? 2   GAL C H2     1 
HETATM 4421 H  H3     . GAL C 2  .   ? 29.62922  -2.35607  48.64854  1.000 76.52447  ? 2   GAL C H3     1 
HETATM 4422 H  H4     . GAL C 2  .   ? 27.22373  -2.27488  49.14975  1.000 68.46358  ? 2   GAL C H4     1 
HETATM 4423 H  H5     . GAL C 2  .   ? 27.90937  -3.69083  47.32883  1.000 72.21459  ? 2   GAL C H5     1 
HETATM 4424 H  H61    . GAL C 2  .   ? 25.25297  -2.52241  47.37572  1.000 77.79882  ? 2   GAL C H61    1 
HETATM 4425 H  H62    . GAL C 2  .   ? 25.71021  -4.09685  46.69405  1.000 77.79882  ? 2   GAL C H62    1 
HETATM 4426 H  HO2    . GAL C 2  .   ? 31.11478  -0.62826  48.22322  1.000 90.04605  ? 2   GAL C HO2    1 
HETATM 4427 H  HO3    . GAL C 2  .   ? 28.97877  0.37552   49.11152  1.000 74.58111  ? 2   GAL C HO3    1 
HETATM 4428 H  HO6    . GAL C 2  .   ? 26.35781  -2.68161  44.82721  1.000 85.94323  ? 2   GAL C HO6    1 
HETATM 4429 C  C1     . GLA C 2  .   ? 25.78683  -0.25212  48.82513  1.000 36.65647  ? 3   GLA C C1     1 
HETATM 4430 C  C2     . GLA C 2  .   ? 24.67027  0.41380   48.02559  1.000 30.36424  ? 3   GLA C C2     1 
HETATM 4431 C  C3     . GLA C 2  .   ? 25.07399  1.77958   47.56057  1.000 27.63193  ? 3   GLA C C3     1 
HETATM 4432 C  C4     . GLA C 2  .   ? 25.47918  2.60384   48.75080  1.000 27.79397  ? 3   GLA C C4     1 
HETATM 4433 C  C5     . GLA C 2  .   ? 26.63773  1.96777   49.51073  1.000 34.09971  ? 3   GLA C C5     1 
HETATM 4434 C  C6     . GLA C 2  .   ? 26.99057  2.73755   50.74722  1.000 38.05576  ? 3   GLA C C6     1 
HETATM 4435 O  O2     . GLA C 2  .   ? 24.35042  -0.37759  46.87038  1.000 32.54553  ? 3   GLA C O2     1 
HETATM 4436 O  O3     . GLA C 2  .   ? 23.95923  2.42614   46.89795  1.000 23.87462  ? 3   GLA C O3     1 
HETATM 4437 O  O4     . GLA C 2  .   ? 24.37246  2.62600   49.64760  1.000 28.27824  ? 3   GLA C O4     1 
HETATM 4438 O  O5     . GLA C 2  .   ? 26.28085  0.59904   49.96170  1.000 32.07380  ? 3   GLA C O5     1 
HETATM 4439 O  O6     . GLA C 2  .   ? 28.10608  2.10098   51.33848  1.000 57.55259  ? 3   GLA C O6     1 
HETATM 4440 H  H1     . GLA C 2  .   ? 25.41835  -1.06445  49.20625  1.000 44.01542  ? 3   GLA C H1     1 
HETATM 4441 H  H2     . GLA C 2  .   ? 23.88264  0.47010   48.58895  1.000 36.46475  ? 3   GLA C H2     1 
HETATM 4442 H  H3     . GLA C 2  .   ? 25.79681  1.71439   46.91699  1.000 33.18598  ? 3   GLA C H3     1 
HETATM 4443 H  H4     . GLA C 2  .   ? 25.72216  3.49558   48.45641  1.000 33.38042  ? 3   GLA C H4     1 
HETATM 4444 H  H5     . GLA C 2  .   ? 27.40317  1.97685   48.91498  1.000 40.94731  ? 3   GLA C H5     1 
HETATM 4445 H  H61    . GLA C 2  .   ? 26.24203  2.73500   51.36412  1.000 45.69457  ? 3   GLA C H61    1 
HETATM 4446 H  H62    . GLA C 2  .   ? 27.21533  3.65222   50.51536  1.000 45.69457  ? 3   GLA C H62    1 
HETATM 4447 H  HO2    . GLA C 2  .   ? 24.57757  0.04225   46.16038  1.000 39.08230  ? 3   GLA C HO2    1 
HETATM 4448 H  HO4    . GLA C 2  .   ? 23.97417  3.37285   49.59050  1.000 33.96155  ? 3   GLA C HO4    1 
HETATM 4449 H  HO6    . GLA C 2  .   ? 28.28114  1.38388   50.91432  1.000 69.09077  ? 3   GLA C HO6    1 
HETATM 4450 C  C1     . NGA C 2  .   ? 24.39862  3.28757   45.83377  1.000 23.51477  ? 4   NGA C C1     1 
HETATM 4451 C  C2     . NGA C 2  .   ? 23.31889  3.33258   44.75790  1.000 27.30257  ? 4   NGA C C2     1 
HETATM 4452 C  C3     . NGA C 2  .   ? 23.72810  4.30265   43.66014  1.000 27.31149  ? 4   NGA C C3     1 
HETATM 4453 C  C4     . NGA C 2  .   ? 24.12715  5.67135   44.22936  1.000 26.81583  ? 4   NGA C C4     1 
HETATM 4454 C  C5     . NGA C 2  .   ? 25.14992  5.47384   45.34795  1.000 23.10075  ? 4   NGA C C5     1 
HETATM 4455 C  C6     . NGA C 2  .   ? 25.53931  6.79134   46.02874  1.000 20.00394  ? 4   NGA C C6     1 
HETATM 4456 C  C7     . NGA C 2  .   ? 22.03388  1.23647   44.45314  1.000 30.54956  ? 4   NGA C C7     1 
HETATM 4457 C  C8     . NGA C 2  .   ? 22.16330  -0.24577  44.20229  1.000 25.82085  ? 4   NGA C C8     1 
HETATM 4458 N  N2     . NGA C 2  .   ? 23.09767  2.00483   44.17257  1.000 24.43742  ? 4   NGA C N2     1 
HETATM 4459 O  O3     . NGA C 2  .   ? 22.67317  4.46598   42.70511  1.000 23.05894  ? 4   NGA C O3     1 
HETATM 4460 O  O4     . NGA C 2  .   ? 23.00659  6.37796   44.71250  1.000 24.11544  ? 4   NGA C O4     1 
HETATM 4461 O  O5     . NGA C 2  .   ? 24.64194  4.60202   46.34249  1.000 22.10365  ? 4   NGA C O5     1 
HETATM 4462 O  O6     . NGA C 2  .   ? 26.60960  6.51348   46.91721  1.000 22.49478  ? 4   NGA C O6     1 
HETATM 4463 O  O7     . NGA C 2  .   ? 20.96820  1.68379   44.86151  1.000 23.99591  ? 4   NGA C O7     1 
HETATM 4464 H  H1     . NGA C 2  .   ? 25.30781  2.90079   45.37348  1.000 28.24538  ? 4   NGA C H1     1 
HETATM 4465 H  H2     . NGA C 2  .   ? 22.39005  3.65321   45.22964  1.000 32.79074  ? 4   NGA C H2     1 
HETATM 4466 H  H3     . NGA C 2  .   ? 24.59997  3.88588   43.15591  1.000 32.80145  ? 4   NGA C H3     1 
HETATM 4467 H  H4     . NGA C 2  .   ? 24.57741  6.24436   43.41879  1.000 32.20666  ? 4   NGA C H4     1 
HETATM 4468 H  H5     . NGA C 2  .   ? 26.05090  5.05205   44.90251  1.000 27.74856  ? 4   NGA C H5     1 
HETATM 4469 H  H61    . NGA C 2  .   ? 24.68984  7.20133   46.57500  1.000 24.03239  ? 4   NGA C H61    1 
HETATM 4470 H  H62    . NGA C 2  .   ? 25.84549  7.52657   45.28457  1.000 24.03239  ? 4   NGA C H62    1 
HETATM 4471 H  H81    . NGA C 2  .   ? 23.22599  -0.49705  44.14565  1.000 31.01268  ? 4   NGA C H81    1 
HETATM 4472 H  H82    . NGA C 2  .   ? 21.69092  -0.49920  43.25698  1.000 31.01268  ? 4   NGA C H82    1 
HETATM 4473 H  HN2    . NGA C 2  .   ? 23.79162  1.66138   43.52405  1.000 29.35256  ? 4   NGA C HN2    1 
HETATM 4474 H  HO3    . NGA C 2  .   ? 22.68460  3.71606   42.07433  1.000 27.69839  ? 4   NGA C HO3    1 
HETATM 4475 H  HO4    . NGA C 2  .   ? 22.71316  5.98451   45.56073  1.000 28.96619  ? 4   NGA C HO4    1 
HETATM 4476 H  HO6    . NGA C 2  .   ? 26.85560  7.33117   47.39810  1.000 27.02139  ? 4   NGA C HO6    1 
HETATM 4477 C  C2     . BGC D 2  .   ? 2.62688   4.61160   11.95160  1.000 115.28469 ? 1   BGC D C2     1 
HETATM 4478 C  C3     . BGC D 2  .   ? 1.48939   5.62749   11.90564  1.000 106.17606 ? 1   BGC D C3     1 
HETATM 4479 C  C4     . BGC D 2  .   ? 1.83362   6.75608   10.94170  1.000 101.69460 ? 1   BGC D C4     1 
HETATM 4480 C  C5     . BGC D 2  .   ? 2.19555   6.18783   9.56892   1.000 99.46946  ? 1   BGC D C5     1 
HETATM 4481 C  C6     . BGC D 2  .   ? 2.67136   7.24669   8.60146   1.000 85.23363  ? 1   BGC D C6     1 
HETATM 4482 C  C1     . BGC D 2  .   ? 2.96753   4.12670   10.54626  1.000 111.20515 ? 1   BGC D C1     1 
HETATM 4483 O  O1     . BGC D 2  .   ? 4.05566   3.26033   10.60853  1.000 109.05705 ? 1   BGC D O1     1 
HETATM 4484 O  O2     . BGC D 2  .   ? 2.26892   3.49760   12.76448  1.000 127.55849 ? 1   BGC D O2     1 
HETATM 4485 O  O3     . BGC D 2  .   ? 1.23911   6.15049   13.20624  1.000 95.42073  ? 1   BGC D O3     1 
HETATM 4486 O  O4     . BGC D 2  .   ? 0.77014   7.70068   10.84416  1.000 88.52299  ? 1   BGC D O4     1 
HETATM 4487 O  O5     . BGC D 2  .   ? 3.27228   5.24445   9.70138   1.000 112.05493 ? 1   BGC D O5     1 
HETATM 4488 O  O6     . BGC D 2  .   ? 3.46818   6.69409   7.56026   1.000 81.69274  ? 1   BGC D O6     1 
HETATM 4489 C  C1     . GAL D 2  .   ? -0.51921  7.07603   10.63969  1.000 83.14615  ? 2   GAL D C1     1 
HETATM 4490 C  C2     . GAL D 2  .   ? -1.61128  8.17982   10.75599  1.000 72.73573  ? 2   GAL D C2     1 
HETATM 4491 C  C3     . GAL D 2  .   ? -2.99345  7.68134   10.40805  1.000 71.81588  ? 2   GAL D C3     1 
HETATM 4492 C  C4     . GAL D 2  .   ? -2.94115  7.24079   8.94920   1.000 64.92616  ? 2   GAL D C4     1 
HETATM 4493 C  C5     . GAL D 2  .   ? -1.90114  6.11528   8.81236   1.000 66.22878  ? 2   GAL D C5     1 
HETATM 4494 C  C6     . GAL D 2  .   ? -1.53922  5.69791   7.36791   1.000 67.16633  ? 2   GAL D C6     1 
HETATM 4495 O  O2     . GAL D 2  .   ? -1.65225  8.80037   12.04926  1.000 70.26488  ? 2   GAL D O2     1 
HETATM 4496 O  O3     . GAL D 2  .   ? -3.94414  8.71965   10.51107  1.000 70.54780  ? 2   GAL D O3     1 
HETATM 4497 O  O4     . GAL D 2  .   ? -2.63094  8.34110   8.11462   1.000 53.64379  ? 2   GAL D O4     1 
HETATM 4498 O  O5     . GAL D 2  .   ? -0.59534  6.40711   9.37874   1.000 80.38789  ? 2   GAL D O5     1 
HETATM 4499 O  O6     . GAL D 2  .   ? -0.12668  5.80353   7.18720   1.000 78.76999  ? 2   GAL D O6     1 
HETATM 4500 C  C1     . GLA D 2  .   ? -3.73693  8.61411   7.22606   1.000 54.51176  ? 3   GLA D C1     1 
HETATM 4501 C  C2     . GLA D 2  .   ? -3.22986  9.33705   5.98524   1.000 48.66871  ? 3   GLA D C2     1 
HETATM 4502 C  C3     . GLA D 2  .   ? -2.80152  10.72769  6.33976   1.000 47.68950  ? 3   GLA D C3     1 
HETATM 4503 C  C4     . GLA D 2  .   ? -3.92329  11.47912  6.99992   1.000 48.34747  ? 3   GLA D C4     1 
HETATM 4504 C  C5     . GLA D 2  .   ? -4.39533  10.76331  8.27434   1.000 52.75891  ? 3   GLA D C5     1 
HETATM 4505 C  C6     . GLA D 2  .   ? -5.55737  11.47659  8.90651   1.000 55.20522  ? 3   GLA D C6     1 
HETATM 4506 O  O2     . GLA D 2  .   ? -2.13754  8.59143   5.40480   1.000 42.59573  ? 3   GLA D O2     1 
HETATM 4507 O  O3     . GLA D 2  .   ? -2.38438  11.38798  5.12454   1.000 37.54600  ? 3   GLA D O3     1 
HETATM 4508 O  O4     . GLA D 2  .   ? -5.01631  11.58110  6.09152   1.000 40.14417  ? 3   GLA D O4     1 
HETATM 4509 O  O5     . GLA D 2  .   ? -4.80466  9.37648   7.96164   1.000 44.23759  ? 3   GLA D O5     1 
HETATM 4510 O  O6     . GLA D 2  .   ? -5.78061  10.90923  10.18277  1.000 66.44610  ? 3   GLA D O6     1 
HETATM 4511 H  H1     . GLA D 2  .   ? -4.11934  7.78231   6.90549   1.000 65.44177  ? 3   GLA D H1     1 
HETATM 4512 H  H2     . GLA D 2  .   ? -3.92453  9.38199   5.30973   1.000 58.43011  ? 3   GLA D H2     1 
HETATM 4513 H  H3     . GLA D 2  .   ? -2.04715  10.71541  6.94941   1.000 57.25506  ? 3   GLA D H3     1 
HETATM 4514 H  H4     . GLA D 2  .   ? -3.62330  12.37394  7.22400   1.000 58.04463  ? 3   GLA D H4     1 
HETATM 4515 H  H5     . GLA D 2  .   ? -3.66989  10.77706  8.91812   1.000 63.33834  ? 3   GLA D H5     1 
HETATM 4516 H  H61    . GLA D 2  .   ? -6.34849  11.36835  8.35578   1.000 66.27392  ? 3   GLA D H61    1 
HETATM 4517 H  H62    . GLA D 2  .   ? -5.35349  12.42054  8.99757   1.000 66.27392  ? 3   GLA D H62    1 
HETATM 4518 H  HO2    . GLA D 2  .   ? -1.41662  9.03289   5.49129   1.000 51.14254  ? 3   GLA D HO2    1 
HETATM 4519 H  HO4    . GLA D 2  .   ? -5.53448  10.91705  6.18999   1.000 48.20067  ? 3   GLA D HO4    1 
HETATM 4520 H  HO6    . GLA D 2  .   ? -6.44170  11.28930  10.56014  1.000 79.76298  ? 3   GLA D HO6    1 
HETATM 4521 C  C1     . NGA D 2  .   ? -1.23406  12.21757  5.34734   1.000 42.09797  ? 4   NGA D C1     1 
HETATM 4522 C  C2     . NGA D 2  .   ? -0.43477  12.30388  4.04340   1.000 41.17293  ? 4   NGA D C2     1 
HETATM 4523 C  C3     . NGA D 2  .   ? 0.76098   13.22569  4.26124   1.000 44.06389  ? 4   NGA D C3     1 
HETATM 4524 C  C4     . NGA D 2  .   ? 0.32806   14.58372  4.82380   1.000 42.14226  ? 4   NGA D C4     1 
HETATM 4525 C  C5     . NGA D 2  .   ? -0.53674  14.35429  6.06222   1.000 43.22869  ? 4   NGA D C5     1 
HETATM 4526 C  C6     . NGA D 2  .   ? -1.08176  15.67127  6.61888   1.000 34.30765  ? 4   NGA D C6     1 
HETATM 4527 C  C7     . NGA D 2  .   ? -0.56151  10.25458  2.67708   1.000 45.95866  ? 4   NGA D C7     1 
HETATM 4528 C  C8     . NGA D 2  .   ? -0.29652  8.78270   2.71786   1.000 41.77297  ? 4   NGA D C8     1 
HETATM 4529 N  N2     . NGA D 2  .   ? 0.02906   10.97960  3.63585   1.000 39.83563  ? 4   NGA D N2     1 
HETATM 4530 O  O3     . NGA D 2  .   ? 1.52120   13.35475  3.07894   1.000 34.65189  ? 4   NGA D O3     1 
HETATM 4531 O  O4     . NGA D 2  .   ? -0.42543  15.30291  3.86140   1.000 37.75675  ? 4   NGA D O4     1 
HETATM 4532 O  O5     . NGA D 2  .   ? -1.62757  13.51785  5.74103   1.000 36.19204  ? 4   NGA D O5     1 
HETATM 4533 O  O6     . NGA D 2  .   ? -1.74500  15.49123  7.86077   1.000 30.90781  ? 4   NGA D O6     1 
HETATM 4534 O  O7     . NGA D 2  .   ? -1.29573  10.72037  1.80570   1.000 42.59063  ? 4   NGA D O7     1 
HETATM 4535 H  H1     . NGA D 2  .   ? -0.59891  11.78087  6.11804   1.000 50.54522  ? 4   NGA D H1     1 
HETATM 4536 H  H2     . NGA D 2  .   ? -1.09500  12.68945  3.26652   1.000 49.43517  ? 4   NGA D H2     1 
HETATM 4537 H  H3     . NGA D 2  .   ? 1.38604   12.78086  5.03553   1.000 52.90433  ? 4   NGA D H3     1 
HETATM 4538 H  H4     . NGA D 2  .   ? 1.22829   15.14872  5.06555   1.000 50.59837  ? 4   NGA D H4     1 
HETATM 4539 H  H5     . NGA D 2  .   ? 0.08547   13.89364  6.82953   1.000 51.90209  ? 4   NGA D H5     1 
HETATM 4540 H  H61    . NGA D 2  .   ? -1.77794  16.10342  5.90008   1.000 41.19684  ? 4   NGA D H61    1 
HETATM 4541 H  H62    . NGA D 2  .   ? -0.25803  16.37281  6.75086   1.000 41.19684  ? 4   NGA D H62    1 
HETATM 4542 H  H81    . NGA D 2  .   ? 0.04822   8.49889   3.71275   1.000 50.15522  ? 4   NGA D H81    1 
HETATM 4543 H  H82    . NGA D 2  .   ? 0.46202   8.52877   1.98019   1.000 50.15522  ? 4   NGA D H82    1 
HETATM 4544 H  H83    . NGA D 2  .   ? -1.21612  8.23201   2.53367   1.000 50.15522  ? 4   NGA D H83    1 
HETATM 4545 H  HN2    . NGA D 2  .   ? 0.83767   10.60221  4.10896   1.000 47.83042  ? 4   NGA D HN2    1 
HETATM 4546 H  HO3    . NGA D 2  .   ? 0.96432   13.12537  2.30585   1.000 41.60993  ? 4   NGA D HO3    1 
HETATM 4547 H  HO4    . NGA D 2  .   ? -1.32418  14.91776  3.79590   1.000 45.33576  ? 4   NGA D HO4    1 
HETATM 4548 H  HO6    . NGA D 2  .   ? -1.90403  14.53591  8.01067   1.000 37.11703  ? 4   NGA D HO6    1 
HETATM 4549 C  C1     . NAG E 3  .   ? 26.65075  14.43963  28.67009  1.000 42.32483  ? 1   NAG E C1     1 
HETATM 4550 C  C2     . NAG E 3  .   ? 28.17008  14.43438  28.55029  1.000 39.02358  ? 1   NAG E C2     1 
HETATM 4551 C  C3     . NAG E 3  .   ? 28.67316  15.82022  28.12718  1.000 43.98729  ? 1   NAG E C3     1 
HETATM 4552 C  C4     . NAG E 3  .   ? 27.93415  16.32805  26.89627  1.000 41.96918  ? 1   NAG E C4     1 
HETATM 4553 C  C5     . NAG E 3  .   ? 26.42972  16.24609  27.13120  1.000 39.56447  ? 1   NAG E C5     1 
HETATM 4554 C  C6     . NAG E 3  .   ? 25.62074  16.60947  25.91160  1.000 35.25094  ? 1   NAG E C6     1 
HETATM 4555 C  C7     . NAG E 3  .   ? 29.69130  13.09832  29.95685  1.000 38.37551  ? 1   NAG E C7     1 
HETATM 4556 C  C8     . NAG E 3  .   ? 30.21021  12.88012  31.34813  1.000 40.83975  ? 1   NAG E C8     1 
HETATM 4557 N  N2     . NAG E 3  .   ? 28.77022  14.05983  29.82064  1.000 38.68367  ? 1   NAG E N2     1 
HETATM 4558 O  O3     . NAG E 3  .   ? 30.06850  15.73644  27.85838  1.000 51.19323  ? 1   NAG E O3     1 
HETATM 4559 O  O4     . NAG E 3  .   ? 28.29098  17.68789  26.65225  1.000 56.12928  ? 1   NAG E O4     1 
HETATM 4560 O  O5     . NAG E 3  .   ? 26.07464  14.89281  27.45318  1.000 41.02368  ? 1   NAG E O5     1 
HETATM 4561 O  O6     . NAG E 3  .   ? 25.78619  15.61605  24.90807  1.000 38.02810  ? 1   NAG E O6     1 
HETATM 4562 O  O7     . NAG E 3  .   ? 30.06901  12.42067  29.00861  1.000 42.79845  ? 1   NAG E O7     1 
HETATM 4563 H  H1     . NAG E 3  .   ? 26.38753  15.03983  29.39332  1.000 50.81745  ? 1   NAG E H1     1 
HETATM 4564 H  H2     . NAG E 3  .   ? 28.42682  13.79208  27.86172  1.000 46.85595  ? 1   NAG E H2     1 
HETATM 4565 H  H3     . NAG E 3  .   ? 28.51321  16.44930  28.85605  1.000 52.81240  ? 1   NAG E H3     1 
HETATM 4566 H  H4     . NAG E 3  .   ? 28.17380  15.78466  26.12175  1.000 50.39067  ? 1   NAG E H4     1 
HETATM 4567 H  H5     . NAG E 3  .   ? 26.18848  16.83864  27.86826  1.000 47.50502  ? 1   NAG E H5     1 
HETATM 4568 H  H61    . NAG E 3  .   ? 25.92071  17.47216  25.56756  1.000 42.32879  ? 1   NAG E H61    1 
HETATM 4569 H  H62    . NAG E 3  .   ? 24.67744  16.67266  26.15403  1.000 42.32879  ? 1   NAG E H62    1 
HETATM 4570 H  H81    . NAG E 3  .   ? 30.67289  13.68376  31.65254  1.000 49.03535  ? 1   NAG E H81    1 
HETATM 4571 H  H82    . NAG E 3  .   ? 30.83107  12.12706  31.34939  1.000 49.03535  ? 1   NAG E H82    1 
HETATM 4572 H  H83    . NAG E 3  .   ? 29.46408  12.68765  31.94716  1.000 49.03535  ? 1   NAG E H83    1 
HETATM 4573 H  HN2    . NAG E 3  .   ? 28.50301  14.50683  30.56933  1.000 46.44806  ? 1   NAG E HN2    1 
HETATM 4574 H  HO3    . NAG E 3  .   ? 30.19077  15.56094  26.99634  1.000 61.45953  ? 1   NAG E HO3    1 
HETATM 4575 H  HO6    . NAG E 3  .   ? 26.52782  15.77681  24.44594  1.000 45.66138  ? 1   NAG E HO6    1 
HETATM 4576 C  C1     . NAG E 3  .   ? 28.77691  17.85267  25.29013  1.000 64.14356  ? 2   NAG E C1     1 
HETATM 4577 C  C2     . NAG E 3  .   ? 28.94150  19.34362  24.96588  1.000 66.33099  ? 2   NAG E C2     1 
HETATM 4578 C  C3     . NAG E 3  .   ? 29.63877  19.53432  23.61290  1.000 80.38077  ? 2   NAG E C3     1 
HETATM 4579 C  C4     . NAG E 3  .   ? 30.89125  18.67846  23.46826  1.000 88.83371  ? 2   NAG E C4     1 
HETATM 4580 C  C5     . NAG E 3  .   ? 30.56698  17.23301  23.80484  1.000 84.58386  ? 2   NAG E C5     1 
HETATM 4581 C  C6     . NAG E 3  .   ? 31.76298  16.31130  23.78557  1.000 85.84437  ? 2   NAG E C6     1 
HETATM 4582 C  C7     . NAG E 3  .   ? 26.92148  20.26195  26.03461  1.000 59.69316  ? 2   NAG E C7     1 
HETATM 4583 C  C8     . NAG E 3  .   ? 25.59492  20.91092  25.80493  1.000 56.10743  ? 2   NAG E C8     1 
HETATM 4584 N  N2     . NAG E 3  .   ? 27.63648  19.98690  24.93920  1.000 53.94438  ? 2   NAG E N2     1 
HETATM 4585 O  O3     . NAG E 3  .   ? 29.97546  20.90636  23.45039  1.000 78.08523  ? 2   NAG E O3     1 
HETATM 4586 O  O4     . NAG E 3  .   ? 31.36806  18.75546  22.12860  1.000 96.18470  ? 2   NAG E O4     1 
HETATM 4587 O  O5     . NAG E 3  .   ? 30.01578  17.18256  25.12921  1.000 69.29106  ? 2   NAG E O5     1 
HETATM 4588 O  O6     . NAG E 3  .   ? 31.42293  15.05455  24.35571  1.000 76.13566  ? 2   NAG E O6     1 
HETATM 4589 O  O7     . NAG E 3  .   ? 27.32068  19.98685  27.15611  1.000 64.45727  ? 2   NAG E O7     1 
HETATM 4590 H  H1     . NAG E 3  .   ? 28.12229  17.49457  24.66100  1.000 76.99992  ? 2   NAG E H1     1 
HETATM 4591 H  H2     . NAG E 3  .   ? 29.50543  19.74876  25.65175  1.000 79.62485  ? 2   NAG E H2     1 
HETATM 4592 H  H3     . NAG E 3  .   ? 29.01136  19.25523  22.91933  1.000 96.48458  ? 2   NAG E H3     1 
HETATM 4593 H  H4     . NAG E 3  .   ? 31.58382  19.00154  24.07533  1.000 106.62811 ? 2   NAG E H4     1 
HETATM 4594 H  H5     . NAG E 3  .   ? 29.91849  16.89176  23.16018  1.000 101.52829 ? 2   NAG E H5     1 
HETATM 4595 H  H61    . NAG E 3  .   ? 32.49001  16.71321  24.29790  1.000 103.04090 ? 2   NAG E H61    1 
HETATM 4596 H  H62    . NAG E 3  .   ? 32.05605  16.18009  22.86391  1.000 103.04090 ? 2   NAG E H62    1 
HETATM 4597 H  H81    . NAG E 3  .   ? 25.69804  21.88104  25.83361  1.000 67.35657  ? 2   NAG E H81    1 
HETATM 4598 H  H82    . NAG E 3  .   ? 24.97034  20.62943  26.50009  1.000 67.35657  ? 2   NAG E H82    1 
HETATM 4599 H  H83    . NAG E 3  .   ? 25.25013  20.64608  24.93111  1.000 67.35657  ? 2   NAG E H83    1 
HETATM 4600 H  HN2    . NAG E 3  .   ? 27.28645  20.21547  24.12866  1.000 64.76092  ? 2   NAG E HN2    1 
HETATM 4601 H  HO3    . NAG E 3  .   ? 30.44504  21.15594  24.16003  1.000 93.72993  ? 2   NAG E HO3    1 
HETATM 4602 H  HO4    . NAG E 3  .   ? 30.86815  19.32951  21.67177  1.000 115.44930 ? 2   NAG E HO4    1 
HETATM 4603 H  HO6    . NAG E 3  .   ? 30.63032  15.12912  24.74970  1.000 91.39045  ? 2   NAG E HO6    1 
HETATM 4604 C  C1     . NAG F 4  .   ? -7.36189  2.72061   51.66462  1.000 67.51050  ? 1   NAG F C1     1 
HETATM 4605 C  C2     . NAG F 4  .   ? -6.87747  2.05589   52.94946  1.000 71.19136  ? 1   NAG F C2     1 
HETATM 4606 C  C3     . NAG F 4  .   ? -7.63479  0.75296   53.18678  1.000 77.50059  ? 1   NAG F C3     1 
HETATM 4607 C  C4     . NAG F 4  .   ? -9.14131  0.96916   53.10966  1.000 85.00871  ? 1   NAG F C4     1 
HETATM 4608 C  C5     . NAG F 4  .   ? -9.52716  1.76635   51.86144  1.000 77.73005  ? 1   NAG F C5     1 
HETATM 4609 C  C6     . NAG F 4  .   ? -10.97759 2.19329   51.85523  1.000 76.56958  ? 1   NAG F C6     1 
HETATM 4610 C  C7     . NAG F 4  .   ? -4.62791  2.06969   53.92448  1.000 69.47782  ? 1   NAG F C7     1 
HETATM 4611 C  C8     . NAG F 4  .   ? -3.18350  1.73956   53.70556  1.000 62.86937  ? 1   NAG F C8     1 
HETATM 4612 N  N2     . NAG F 4  .   ? -5.44707  1.80656   52.90294  1.000 67.04156  ? 1   NAG F N2     1 
HETATM 4613 O  O3     . NAG F 4  .   ? -7.27662  0.22922   54.46175  1.000 77.46591  ? 1   NAG F O3     1 
HETATM 4614 O  O4     . NAG F 4  .   ? -9.74808  -0.31822  53.03418  1.000 95.00995  ? 1   NAG F O4     1 
HETATM 4615 O  O5     . NAG F 4  .   ? -8.74877  2.96718   51.75612  1.000 65.30958  ? 1   NAG F O5     1 
HETATM 4616 O  O6     . NAG F 4  .   ? -11.33001 2.89302   53.03966  1.000 81.62938  ? 1   NAG F O6     1 
HETATM 4617 O  O7     . NAG F 4  .   ? -5.03376  2.56116   54.97491  1.000 70.88528  ? 1   NAG F O7     1 
HETATM 4618 H  H1     . NAG F 4  .   ? -7.18820  2.12799   50.90883  1.000 81.04026  ? 1   NAG F H1     1 
HETATM 4619 H  H2     . NAG F 4  .   ? -7.06619  2.65902   53.69323  1.000 85.45729  ? 1   NAG F H2     1 
HETATM 4620 H  H3     . NAG F 4  .   ? -7.38314  0.11400   52.49325  1.000 93.02836  ? 1   NAG F H3     1 
HETATM 4621 H  H4     . NAG F 4  .   ? -9.44757  1.46911   53.88994  1.000 102.03811 ? 1   NAG F H4     1 
HETATM 4622 H  H5     . NAG F 4  .   ? -9.34450  1.21183   51.07931  1.000 93.30372  ? 1   NAG F H5     1 
HETATM 4623 H  H61    . NAG F 4  .   ? -11.54095 1.40019   51.77651  1.000 91.91115  ? 1   NAG F H61    1 
HETATM 4624 H  H62    . NAG F 4  .   ? -11.13369 2.77371   51.08626  1.000 91.91115  ? 1   NAG F H62    1 
HETATM 4625 H  H81    . NAG F 4  .   ? -3.09532  0.79139   53.49159  1.000 75.47090  ? 1   NAG F H81    1 
HETATM 4626 H  H82    . NAG F 4  .   ? -2.67782  1.93854   54.51628  1.000 75.47090  ? 1   NAG F H82    1 
HETATM 4627 H  H83    . NAG F 4  .   ? -2.83617  2.27362   52.96616  1.000 75.47090  ? 1   NAG F H83    1 
HETATM 4628 H  HN2    . NAG F 4  .   ? -5.09192  1.45388   52.14056  1.000 80.47753  ? 1   NAG F HN2    1 
HETATM 4629 H  HO3    . NAG F 4  .   ? -8.01238  -0.01395  54.89464  1.000 92.98675  ? 1   NAG F HO3    1 
HETATM 4630 C  C1     . NAG F 4  .   ? -10.91052 -0.46975  53.88180  1.000 105.86105 ? 2   NAG F C1     1 
HETATM 4631 C  C2     . NAG F 4  .   ? -11.47768 -1.86268  53.67663  1.000 113.58819 ? 2   NAG F C2     1 
HETATM 4632 C  C3     . NAG F 4  .   ? -12.75316 -2.01233  54.50051  1.000 124.14975 ? 2   NAG F C3     1 
HETATM 4633 C  C4     . NAG F 4  .   ? -12.42241 -1.79496  55.97539  1.000 125.16919 ? 2   NAG F C4     1 
HETATM 4634 C  C5     . NAG F 4  .   ? -11.67792 -0.46889  56.19459  1.000 114.52124 ? 2   NAG F C5     1 
HETATM 4635 C  C6     . NAG F 4  .   ? -11.06500 -0.37112  57.57447  1.000 112.48674 ? 2   NAG F C6     1 
HETATM 4636 C  C7     . NAG F 4  .   ? -12.46352 -1.62466  51.38243  1.000 105.29354 ? 2   NAG F C7     1 
HETATM 4637 C  C8     . NAG F 4  .   ? -13.23398 -0.43074  51.85565  1.000 96.99160  ? 2   NAG F C8     1 
HETATM 4638 N  N2     . NAG F 4  .   ? -11.67436 -2.23731  52.27916  1.000 109.40389 ? 2   NAG F N2     1 
HETATM 4639 O  O3     . NAG F 4  .   ? -13.33206 -3.29632  54.31076  1.000 123.81187 ? 2   NAG F O3     1 
HETATM 4640 O  O4     . NAG F 4  .   ? -13.59993 -1.80592  56.77937  1.000 121.08671 ? 2   NAG F O4     1 
HETATM 4641 O  O5     . NAG F 4  .   ? -10.58684 -0.29341  55.26911  1.000 109.51948 ? 2   NAG F O5     1 
HETATM 4642 O  O6     . NAG F 4  .   ? -9.89563  -1.17459  57.68281  1.000 109.86169 ? 2   NAG F O6     1 
HETATM 4643 O  O7     . NAG F 4  .   ? -12.56266 -2.03748  50.23309  1.000 105.67453 ? 2   NAG F O7     1 
HETATM 4644 H  H1     . NAG F 4  .   ? -11.58246 0.19204   53.63057  1.000 127.06092 ? 2   NAG F H1     1 
HETATM 4645 H  H2     . NAG F 4  .   ? -10.81229 -2.49524  54.00783  1.000 136.33349 ? 2   NAG F H2     1 
HETATM 4646 H  H3     . NAG F 4  .   ? -13.40492 -1.35108  54.19962  1.000 149.00736 ? 2   NAG F H3     1 
HETATM 4647 H  H4     . NAG F 4  .   ? -11.84519 -2.53100  56.25405  1.000 150.23068 ? 2   NAG F H4     1 
HETATM 4648 H  H5     . NAG F 4  .   ? -12.31656 0.25326   56.04220  1.000 137.45315 ? 2   NAG F H5     1 
HETATM 4649 H  H61    . NAG F 4  .   ? -11.71852 -0.66886  58.23541  1.000 135.01174 ? 2   NAG F H61    1 
HETATM 4650 H  H62    . NAG F 4  .   ? -10.83020 0.55908   57.75382  1.000 135.01174 ? 2   NAG F H62    1 
HETATM 4651 H  H81    . NAG F 4  .   ? -14.01358 -0.72676  52.36277  1.000 116.41757 ? 2   NAG F H81    1 
HETATM 4652 H  H82    . NAG F 4  .   ? -13.52632 0.09367   51.08616  1.000 116.41757 ? 2   NAG F H82    1 
HETATM 4653 H  H83    . NAG F 4  .   ? -12.66410 0.11887   52.42638  1.000 116.41757 ? 2   NAG F H83    1 
HETATM 4654 H  HN2    . NAG F 4  .   ? -11.21147 -2.96553  51.98392  1.000 131.31233 ? 2   NAG F HN2    1 
HETATM 4655 H  HO3    . NAG F 4  .   ? -12.73409 -3.90280  54.55243  1.000 148.60190 ? 2   NAG F HO3    1 
HETATM 4656 H  HO4    . NAG F 4  .   ? -13.98546 -1.00701  56.74908  1.000 145.33171 ? 2   NAG F HO4    1 
HETATM 4657 H  HO6    . NAG F 4  .   ? -9.57820  -1.36681  56.87593  1.000 131.86169 ? 2   NAG F HO6    1 
HETATM 4658 C  C1     . FUC F 4  .   ? -12.22249 3.98177   52.72180  1.000 72.54346  ? 3   FUC F C1     1 
HETATM 4659 C  C2     . FUC F 4  .   ? -12.55702 4.61062   54.05788  1.000 71.89113  ? 3   FUC F C2     1 
HETATM 4660 C  C3     . FUC F 4  .   ? -11.25788 5.15503   54.68840  1.000 72.84918  ? 3   FUC F C3     1 
HETATM 4661 C  C4     . FUC F 4  .   ? -10.59376 6.18644   53.73845  1.000 75.15114  ? 3   FUC F C4     1 
HETATM 4662 C  C5     . FUC F 4  .   ? -10.39777 5.56175   52.34276  1.000 75.58244  ? 3   FUC F C5     1 
HETATM 4663 C  C6     . FUC F 4  .   ? -9.94291  6.57000   51.27637  1.000 56.86944  ? 3   FUC F C6     1 
HETATM 4664 O  O2     . FUC F 4  .   ? -13.21761 3.68385   54.91356  1.000 74.44212  ? 3   FUC F O2     1 
HETATM 4665 O  O3     . FUC F 4  .   ? -11.50420 5.78944   55.94535  1.000 74.61291  ? 3   FUC F O3     1 
HETATM 4666 O  O4     . FUC F 4  .   ? -11.38527 7.36522   53.62539  1.000 75.59060  ? 3   FUC F O4     1 
HETATM 4667 O  O5     . FUC F 4  .   ? -11.61426 4.92892   51.85208  1.000 70.94983  ? 3   FUC F O5     1 
HETATM 4668 C  C1     . NAG G 3  .   ? 15.91493  22.93437  4.44299   1.000 80.72975  ? 1   NAG G C1     1 
HETATM 4669 C  C2     . NAG G 3  .   ? 16.50529  22.73537  5.85690   1.000 83.86131  ? 1   NAG G C2     1 
HETATM 4670 C  C3     . NAG G 3  .   ? 17.25735  23.98241  6.30168   1.000 92.07323  ? 1   NAG G C3     1 
HETATM 4671 C  C4     . NAG G 3  .   ? 18.27268  24.37254  5.24080   1.000 95.41125  ? 1   NAG G C4     1 
HETATM 4672 C  C5     . NAG G 3  .   ? 17.58518  24.51215  3.88818   1.000 86.11791  ? 1   NAG G C5     1 
HETATM 4673 C  C6     . NAG G 3  .   ? 18.55240  24.84996  2.77627   1.000 86.09820  ? 1   NAG G C6     1 
HETATM 4674 C  C7     . NAG G 3  .   ? 15.71405  21.74095  7.96399   1.000 85.47453  ? 1   NAG G C7     1 
HETATM 4675 C  C8     . NAG G 3  .   ? 14.53420  21.46589  8.79861   1.000 88.59924  ? 1   NAG G C8     1 
HETATM 4676 N  N2     . NAG G 3  .   ? 15.47245  22.38688  6.81839   1.000 79.77811  ? 1   NAG G N2     1 
HETATM 4677 O  O3     . NAG G 3  .   ? 17.87777  23.74275  7.56308   1.000 93.13006  ? 1   NAG G O3     1 
HETATM 4678 O  O4     . NAG G 3  .   ? 18.81845  25.64309  5.56065   1.000 107.67013 ? 1   NAG G O4     1 
HETATM 4679 O  O5     . NAG G 3  .   ? 16.94399  23.27889  3.54392   1.000 84.39526  ? 1   NAG G O5     1 
HETATM 4680 O  O6     . NAG G 3  .   ? 19.82230  24.22107  2.90232   1.000 84.96765  ? 1   NAG G O6     1 
HETATM 4681 O  O7     . NAG G 3  .   ? 16.83493  21.42311  8.31539   1.000 89.18152  ? 1   NAG G O7     1 
HETATM 4682 H  H1     . NAG G 3  .   ? 15.25499  23.65301  4.46778   1.000 96.90336  ? 1   NAG G H1     1 
HETATM 4683 H  H2     . NAG G 3  .   ? 17.14550  21.99996  5.81349   1.000 100.66123 ? 1   NAG G H2     1 
HETATM 4684 H  H3     . NAG G 3  .   ? 16.63378  24.72411  6.41834   1.000 110.51553 ? 1   NAG G H3     1 
HETATM 4685 H  H4     . NAG G 3  .   ? 18.96980  23.69059  5.20146   1.000 114.52116 ? 1   NAG G H4     1 
HETATM 4686 H  H5     . NAG G 3  .   ? 16.90500  25.21044  3.93633   1.000 103.36915 ? 1   NAG G H5     1 
HETATM 4687 H  H61    . NAG G 3  .   ? 18.68681  25.81663  2.76771   1.000 103.34550 ? 1   NAG G H61    1 
HETATM 4688 H  H62    . NAG G 3  .   ? 18.15528  24.57506  1.92815   1.000 103.34550 ? 1   NAG G H62    1 
HETATM 4689 H  H81    . NAG G 3  .   ? 14.72920  21.70170  9.72540   1.000 106.34675 ? 1   NAG G H81    1 
HETATM 4690 H  H82    . NAG G 3  .   ? 14.31127  20.51724  8.74425   1.000 106.34675 ? 1   NAG G H82    1 
HETATM 4691 H  H83    . NAG G 3  .   ? 13.77943  21.99626  8.47985   1.000 106.34675 ? 1   NAG G H83    1 
HETATM 4692 H  HN2    . NAG G 3  .   ? 14.61167  22.62189  6.62975   1.000 95.76139  ? 1   NAG G HN2    1 
HETATM 4693 H  HO3    . NAG G 3  .   ? 18.27279  22.94674  7.59868   1.000 111.78373 ? 1   NAG G HO3    1 
HETATM 4694 H  HO6    . NAG G 3  .   ? 19.74606  23.42051  3.27501   1.000 101.98884 ? 1   NAG G HO6    1 
HETATM 4695 C  C1     . NAG G 3  .   ? 19.87877  25.72586  6.52689   1.000 106.83695 ? 2   NAG G C1     1 
HETATM 4696 C  C2     . NAG G 3  .   ? 21.21714  25.13642  6.03890   1.000 113.71871 ? 2   NAG G C2     1 
HETATM 4697 C  C3     . NAG G 3  .   ? 22.12513  26.23282  5.51291   1.000 113.43218 ? 2   NAG G C3     1 
HETATM 4698 C  C4     . NAG G 3  .   ? 21.27592  27.23907  4.75572   1.000 109.62938 ? 2   NAG G C4     1 
HETATM 4699 C  C5     . NAG G 3  .   ? 20.38527  27.99041  5.73989   1.000 100.38932 ? 2   NAG G C5     1 
HETATM 4700 C  C6     . NAG G 3  .   ? 19.08467  28.43261  5.10774   1.000 88.99322  ? 2   NAG G C6     1 
HETATM 4701 C  C7     . NAG G 3  .   ? 21.81246  23.04947  7.19323   1.000 113.62019 ? 2   NAG G C7     1 
HETATM 4702 C  C8     . NAG G 3  .   ? 22.53609  22.44742  8.34303   1.000 109.70483 ? 2   NAG G C8     1 
HETATM 4703 N  N2     . NAG G 3  .   ? 21.87936  24.38192  7.09431   1.000 115.19117 ? 2   NAG G N2     1 
HETATM 4704 O  O3     . NAG G 3  .   ? 23.10378  25.65277  4.65795   1.000 118.73797 ? 2   NAG G O3     1 
HETATM 4705 O  O4     . NAG G 3  .   ? 22.11114  28.16253  4.07132   1.000 118.25487 ? 2   NAG G O4     1 
HETATM 4706 O  O5     . NAG G 3  .   ? 20.04305  27.14182  6.85029   1.000 103.25734 ? 2   NAG G O5     1 
HETATM 4707 O  O6     . NAG G 3  .   ? 18.00846  28.34739  6.03045   1.000 89.84455  ? 2   NAG G O6     1 
HETATM 4708 O  O7     . NAG G 3  .   ? 21.20445  22.36427  6.38486   1.000 107.96706 ? 2   NAG G O7     1 
HETATM 4709 H  H1     . NAG G 3  .   ? 19.66159  25.17189  7.30053   1.000 128.23199 ? 2   NAG G H1     1 
HETATM 4710 H  H2     . NAG G 3  .   ? 21.02424  24.52984  5.29902   1.000 136.49011 ? 2   NAG G H2     1 
HETATM 4711 H  H3     . NAG G 3  .   ? 22.58858  26.68138  6.24544   1.000 136.14627 ? 2   NAG G H3     1 
HETATM 4712 H  H4     . NAG G 3  .   ? 20.71996  26.77567  4.10093   1.000 131.58291 ? 2   NAG G H4     1 
HETATM 4713 H  H5     . NAG G 3  .   ? 20.86638  28.76673  6.08405   1.000 120.49484 ? 2   NAG G H5     1 
HETATM 4714 H  H61    . NAG G 3  .   ? 18.89260  27.86225  4.33938   1.000 106.81953 ? 2   NAG G H61    1 
HETATM 4715 H  H62    . NAG G 3  .   ? 19.17400  29.35635  4.80559   1.000 106.81953 ? 2   NAG G H62    1 
HETATM 4716 H  H81    . NAG G 3  .   ? 22.28003  22.90686  9.16518   1.000 131.67345 ? 2   NAG G H81    1 
HETATM 4717 H  H82    . NAG G 3  .   ? 23.49809  22.53832  8.20561   1.000 131.67345 ? 2   NAG G H82    1 
HETATM 4718 H  H83    . NAG G 3  .   ? 22.30542  21.50169  8.41344   1.000 131.67345 ? 2   NAG G H83    1 
HETATM 4719 H  HN2    . NAG G 3  .   ? 22.36273  24.83988  7.71751   1.000 138.25706 ? 2   NAG G HN2    1 
HETATM 4720 H  HO3    . NAG G 3  .   ? 22.71577  25.14566  4.03978   1.000 142.51322 ? 2   NAG G HO3    1 
HETATM 4721 H  HO4    . NAG G 3  .   ? 22.94737  27.86430  4.03565   1.000 141.93351 ? 2   NAG G HO4    1 
HETATM 4722 H  HO6    . NAG G 3  .   ? 17.67352  27.52471  6.02523   1.000 107.84111 ? 2   NAG G HO6    1 
HETATM 4723 C  C1     . NAG H 5  .   ? -11.50218 16.44236  -25.76501 1.000 29.72699  ? 1   NAG H C1     1 
HETATM 4724 C  C2     . NAG H 5  .   ? -12.18609 15.52306  -26.80014 1.000 29.09718  ? 1   NAG H C2     1 
HETATM 4725 C  C3     . NAG H 5  .   ? -12.75699 16.34102  -27.95426 1.000 30.55512  ? 1   NAG H C3     1 
HETATM 4726 C  C4     . NAG H 5  .   ? -13.65672 17.44393  -27.43113 1.000 29.72067  ? 1   NAG H C4     1 
HETATM 4727 C  C5     . NAG H 5  .   ? -12.84234 18.30963  -26.47773 1.000 31.23848  ? 1   NAG H C5     1 
HETATM 4728 C  C6     . NAG H 5  .   ? -13.64356 19.42504  -25.85533 1.000 34.04563  ? 1   NAG H C6     1 
HETATM 4729 C  C7     . NAG H 5  .   ? -11.21487 13.24197  -26.96918 1.000 32.38858  ? 1   NAG H C7     1 
HETATM 4730 C  C8     . NAG H 5  .   ? -12.22342 12.78151  -25.95912 1.000 32.99316  ? 1   NAG H C8     1 
HETATM 4731 N  N2     . NAG H 5  .   ? -11.24865 14.53742  -27.31241 1.000 27.80221  ? 1   NAG H N2     1 
HETATM 4732 O  O3     . NAG H 5  .   ? -13.49370 15.50167  -28.83781 1.000 25.41190  ? 1   NAG H O3     1 
HETATM 4733 O  O4     . NAG H 5  .   ? -14.12249 18.17801  -28.55557 1.000 25.85274  ? 1   NAG H O4     1 
HETATM 4734 O  O5     . NAG H 5  .   ? -12.38376 17.49187  -25.39075 1.000 30.58097  ? 1   NAG H O5     1 
HETATM 4735 O  O6     . NAG H 5  .   ? -14.62432 18.88414  -24.98239 1.000 37.63023  ? 1   NAG H O6     1 
HETATM 4736 O  O7     . NAG H 5  .   ? -10.38138 12.47887  -27.44433 1.000 39.96867  ? 1   NAG H O7     1 
HETATM 4737 H  H1     . NAG H 5  .   ? -10.69717 16.82670  -26.16101 1.000 35.70005  ? 1   NAG H H1     1 
HETATM 4738 H  H2     . NAG H 5  .   ? -12.92588 15.06858  -26.35435 1.000 34.94427  ? 1   NAG H H2     1 
HETATM 4739 H  H3     . NAG H 5  .   ? -12.01160 16.73572  -28.44537 1.000 36.69380  ? 1   NAG H H3     1 
HETATM 4740 H  H4     . NAG H 5  .   ? -14.43051 17.10852  -26.93987 1.000 35.69247  ? 1   NAG H H4     1 
HETATM 4741 H  H5     . NAG H 5  .   ? -12.08314 18.69287  -26.95660 1.000 37.51384  ? 1   NAG H H5     1 
HETATM 4742 H  H61    . NAG H 5  .   ? -14.08245 19.94159  -26.55756 1.000 40.88241  ? 1   NAG H H61    1 
HETATM 4743 H  H62    . NAG H 5  .   ? -13.04800 20.01185  -25.35180 1.000 40.88241  ? 1   NAG H H62    1 
HETATM 4744 H  H81    . NAG H 5  .   ? -13.11896 12.84292  -26.34228 1.000 39.61945  ? 1   NAG H H81    1 
HETATM 4745 H  H82    . NAG H 5  .   ? -12.16984 13.34644  -25.16504 1.000 39.61945  ? 1   NAG H H82    1 
HETATM 4746 H  H83    . NAG H 5  .   ? -12.03773 11.85555  -25.71278 1.000 39.61945  ? 1   NAG H H83    1 
HETATM 4747 H  HN2    . NAG H 5  .   ? -10.63103 14.82475  -27.91882 1.000 33.39030  ? 1   NAG H HN2    1 
HETATM 4748 H  HO3    . NAG H 5  .   ? -14.35019 15.73336  -28.80546 1.000 30.52194  ? 1   NAG H HO3    1 
HETATM 4749 C  C1     . NAG H 5  .   ? -15.50582 18.57134  -28.38322 1.000 26.68685  ? 2   NAG H C1     1 
HETATM 4750 C  C2     . NAG H 5  .   ? -15.89554 19.31307  -29.69293 1.000 26.14417  ? 2   NAG H C2     1 
HETATM 4751 C  C3     . NAG H 5  .   ? -17.35967 19.76290  -29.63197 1.000 25.61362  ? 2   NAG H C3     1 
HETATM 4752 C  C4     . NAG H 5  .   ? -18.27729 18.63424  -29.16329 1.000 24.12824  ? 2   NAG H C4     1 
HETATM 4753 C  C5     . NAG H 5  .   ? -17.70952 17.99646  -27.89673 1.000 25.04096  ? 2   NAG H C5     1 
HETATM 4754 C  C6     . NAG H 5  .   ? -18.54495 16.86149  -27.34809 1.000 37.00395  ? 2   NAG H C6     1 
HETATM 4755 C  C7     . NAG H 5  .   ? -13.87196 20.40275  -30.58367 1.000 24.46670  ? 2   NAG H C7     1 
HETATM 4756 C  C8     . NAG H 5  .   ? -13.10820 21.69465  -30.68246 1.000 25.56066  ? 2   NAG H C8     1 
HETATM 4757 N  N2     . NAG H 5  .   ? -15.02339 20.45581  -29.90528 1.000 23.84330  ? 2   NAG H N2     1 
HETATM 4758 O  O3     . NAG H 5  .   ? -17.76432 20.21070  -30.91984 1.000 22.13369  ? 2   NAG H O3     1 
HETATM 4759 O  O4     . NAG H 5  .   ? -19.56215 19.14799  -28.82635 1.000 27.52238  ? 2   NAG H O4     1 
HETATM 4760 O  O5     . NAG H 5  .   ? -16.39957 17.48687  -28.17287 1.000 26.06516  ? 2   NAG H O5     1 
HETATM 4761 O  O6     . NAG H 5  .   ? -18.96996 15.98977  -28.38147 1.000 37.08644  ? 2   NAG H O6     1 
HETATM 4762 O  O7     . NAG H 5  .   ? -13.46410 19.36469  -31.09938 1.000 24.01629  ? 2   NAG H O7     1 
HETATM 4763 H  H1     . NAG H 5  .   ? -15.59009 19.14577  -27.59868 1.000 32.05187  ? 2   NAG H H1     1 
HETATM 4764 H  H2     . NAG H 5  .   ? -15.80232 18.69444  -30.44206 1.000 31.40066  ? 2   NAG H H2     1 
HETATM 4765 H  H3     . NAG H 5  .   ? -17.42806 20.49595  -28.99124 1.000 30.76401  ? 2   NAG H H3     1 
HETATM 4766 H  H4     . NAG H 5  .   ? -18.35105 17.97918  -29.88304 1.000 28.98155  ? 2   NAG H H4     1 
HETATM 4767 H  H5     . NAG H 5  .   ? -17.64639 18.67512  -27.19815 1.000 30.07681  ? 2   NAG H H5     1 
HETATM 4768 H  H61    . NAG H 5  .   ? -19.32893 17.23006  -26.89853 1.000 44.43239  ? 2   NAG H H61    1 
HETATM 4769 H  H62    . NAG H 5  .   ? -18.01427 16.35701  -26.70276 1.000 44.43239  ? 2   NAG H H62    1 
HETATM 4770 H  H81    . NAG H 5  .   ? -13.06789 22.11677  -29.80339 1.000 30.70045  ? 2   NAG H H81    1 
HETATM 4771 H  H82    . NAG H 5  .   ? -13.55850 22.29163  -31.30970 1.000 30.70045  ? 2   NAG H H82    1 
HETATM 4772 H  H83    . NAG H 5  .   ? -12.20262 21.51385  -30.99840 1.000 30.70045  ? 2   NAG H H83    1 
HETATM 4773 H  HN2    . NAG H 5  .   ? -15.27681 21.25854  -29.55434 1.000 28.63962  ? 2   NAG H HN2    1 
HETATM 4774 H  HO3    . NAG H 5  .   ? -18.64041 20.10268  -31.01775 1.000 26.58808  ? 2   NAG H HO3    1 
HETATM 4775 H  HO6    . NAG H 5  .   ? -18.25487 15.62696  -28.75781 1.000 44.53139  ? 2   NAG H HO6    1 
HETATM 4776 C  C1     . BMA H 5  .   ? -20.65034 18.72015  -29.64624 1.000 29.42825  ? 3   BMA H C1     1 
HETATM 4777 C  C2     . BMA H 5  .   ? -21.89269 18.67717  -28.75406 1.000 27.96434  ? 3   BMA H C2     1 
HETATM 4778 C  C3     . BMA H 5  .   ? -23.08806 18.34608  -29.60302 1.000 29.50562  ? 3   BMA H C3     1 
HETATM 4779 C  C4     . BMA H 5  .   ? -23.19983 19.29915  -30.80889 1.000 30.61137  ? 3   BMA H C4     1 
HETATM 4780 C  C5     . BMA H 5  .   ? -21.89300 19.33371  -31.59838 1.000 26.13235  ? 3   BMA H C5     1 
HETATM 4781 C  C6     . BMA H 5  .   ? -21.91026 20.39519  -32.65732 1.000 26.00442  ? 3   BMA H C6     1 
HETATM 4782 O  O2     . BMA H 5  .   ? -22.08104 19.97437  -28.18271 1.000 32.10904  ? 3   BMA H O2     1 
HETATM 4783 O  O3     . BMA H 5  .   ? -24.29314 18.43509  -28.85530 1.000 35.31965  ? 3   BMA H O3     1 
HETATM 4784 O  O4     . BMA H 5  .   ? -24.25490 18.92572  -31.67104 1.000 26.60469  ? 3   BMA H O4     1 
HETATM 4785 O  O5     . BMA H 5  .   ? -20.82855 19.65390  -30.69035 1.000 24.56149  ? 3   BMA H O5     1 
HETATM 4786 O  O6     . BMA H 5  .   ? -22.34461 21.59699  -32.03221 1.000 28.98288  ? 3   BMA H O6     1 
HETATM 4787 H  H1     . BMA H 5  .   ? -20.45713 17.71252  -30.06193 1.000 35.34156  ? 3   BMA H H1     1 
HETATM 4788 H  H2     . BMA H 5  .   ? -21.79867 17.91780  -27.96241 1.000 33.58486  ? 3   BMA H H2     1 
HETATM 4789 H  H3     . BMA H 5  .   ? -22.99706 17.31389  -29.96619 1.000 35.43440  ? 3   BMA H H3     1 
HETATM 4790 H  H4     . BMA H 5  .   ? -23.37004 20.30457  -30.39109 1.000 36.76130  ? 3   BMA H H4     1 
HETATM 4791 H  H5     . BMA H 5  .   ? -21.71030 18.35005  -32.06274 1.000 31.38648  ? 3   BMA H H5     1 
HETATM 4792 H  H61    . BMA H 5  .   ? -22.59164 20.08105  -33.46308 1.000 31.23296  ? 3   BMA H H61    1 
HETATM 4793 H  H62    . BMA H 5  .   ? -20.89743 20.49296  -33.07781 1.000 31.23296  ? 3   BMA H H62    1 
HETATM 4794 H  HO2    . BMA H 5  .   ? -23.03063 20.06058  -28.01177 1.000 38.55850  ? 3   BMA H HO2    1 
HETATM 4795 H  HO4    . BMA H 5  .   ? -24.02025 18.05296  -31.99828 1.000 31.95329  ? 3   BMA H HO4    1 
HETATM 4796 C  C1     . MAN H 5  .   ? -24.76358 17.16391  -28.35596 1.000 35.42517  ? 4   MAN H C1     1 
HETATM 4797 C  C2     . MAN H 5  .   ? -26.25794 17.41515  -28.01517 1.000 45.48626  ? 4   MAN H C2     1 
HETATM 4798 C  C3     . MAN H 5  .   ? -26.29943 18.44339  -26.87331 1.000 41.40584  ? 4   MAN H C3     1 
HETATM 4799 C  C4     . MAN H 5  .   ? -25.43241 17.94710  -25.70138 1.000 37.72906  ? 4   MAN H C4     1 
HETATM 4800 C  C5     . MAN H 5  .   ? -23.98284 17.64337  -26.14469 1.000 43.47023  ? 4   MAN H C5     1 
HETATM 4801 C  C6     . MAN H 5  .   ? -23.15600 17.00870  -25.02171 1.000 50.02366  ? 4   MAN H C6     1 
HETATM 4802 O  O2     . MAN H 5  .   ? -26.92980 16.25691  -27.54425 1.000 51.08838  ? 4   MAN H O2     1 
HETATM 4803 O  O3     . MAN H 5  .   ? -27.61875 18.72325  -26.40226 1.000 46.28993  ? 4   MAN H O3     1 
HETATM 4804 O  O4     . MAN H 5  .   ? -25.39189 18.91172  -24.65528 1.000 45.62979  ? 4   MAN H O4     1 
HETATM 4805 O  O5     . MAN H 5  .   ? -24.01460 16.72224  -27.24807 1.000 33.90137  ? 4   MAN H O5     1 
HETATM 4806 O  O6     . MAN H 5  .   ? -21.94117 16.49004  -25.55112 1.000 46.49927  ? 4   MAN H O6     1 
HETATM 4807 H  H1     . MAN H 5  .   ? -24.62447 16.34852  -29.08258 1.000 42.53786  ? 4   MAN H H1     1 
HETATM 4808 H  H2     . MAN H 5  .   ? -26.78707 17.77254  -28.90842 1.000 54.61117  ? 4   MAN H H2     1 
HETATM 4809 H  H3     . MAN H 5  .   ? -25.91860 19.39654  -27.25474 1.000 49.71467  ? 4   MAN H H3     1 
HETATM 4810 H  H4     . MAN H 5  .   ? -25.88577 16.99704  -25.37204 1.000 45.30254  ? 4   MAN H H4     1 
HETATM 4811 H  H5     . MAN H 5  .   ? -23.49235 18.57261  -26.46334 1.000 52.19193  ? 4   MAN H H5     1 
HETATM 4812 H  H61    . MAN H 5  .   ? -23.76111 16.21269  -24.56083 1.000 60.05606  ? 4   MAN H H61    1 
HETATM 4813 H  H62    . MAN H 5  .   ? -22.96115 17.78218  -24.26280 1.000 60.05606  ? 4   MAN H H62    1 
HETATM 4814 H  HO2    . MAN H 5  .   ? -27.63139 16.54303  -26.94547 1.000 61.33372  ? 4   MAN H HO2    1 
HETATM 4815 H  HO3    . MAN H 5  .   ? -27.67027 18.32303  -25.51656 1.000 55.57557  ? 4   MAN H HO3    1 
HETATM 4816 H  HO4    . MAN H 5  .   ? -24.87901 19.66027  -25.00478 1.000 54.78340  ? 4   MAN H HO4    1 
HETATM 4817 H  HO6    . MAN H 5  .   ? -21.93441 16.67360  -26.48787 1.000 55.82679  ? 4   MAN H HO6    1 
HETATM 4818 C  C1     . MAN H 5  .   ? -22.33537 22.70869  -32.95143 1.000 27.94323  ? 5   MAN H C1     1 
HETATM 4819 C  C2     . MAN H 5  .   ? -22.62748 24.01853  -32.15890 1.000 28.71302  ? 5   MAN H C2     1 
HETATM 4820 C  C3     . MAN H 5  .   ? -24.07442 23.95914  -31.62881 1.000 31.96634  ? 5   MAN H C3     1 
HETATM 4821 C  C4     . MAN H 5  .   ? -25.08045 23.63367  -32.71020 1.000 35.49400  ? 5   MAN H C4     1 
HETATM 4822 C  C5     . MAN H 5  .   ? -24.65939 22.34920  -33.47644 1.000 32.05816  ? 5   MAN H C5     1 
HETATM 4823 C  C6     . MAN H 5  .   ? -25.52378 22.11526  -34.69835 1.000 38.04549  ? 5   MAN H C6     1 
HETATM 4824 O  O2     . MAN H 5  .   ? -22.53683 25.15174  -33.00171 1.000 33.34338  ? 5   MAN H O2     1 
HETATM 4825 O  O3     . MAN H 5  .   ? -24.46517 25.17754  -30.99532 1.000 32.77482  ? 5   MAN H O3     1 
HETATM 4826 O  O4     . MAN H 5  .   ? -26.38295 23.47275  -32.10711 1.000 40.66630  ? 5   MAN H O4     1 
HETATM 4827 O  O5     . MAN H 5  .   ? -23.29991 22.50345  -33.94791 1.000 30.36504  ? 5   MAN H O5     1 
HETATM 4828 O  O6     . MAN H 5  .   ? -25.08331 23.03366  -35.72773 1.000 39.55210  ? 5   MAN H O6     1 
HETATM 4829 H  H1     . MAN H 5  .   ? -21.35830 22.77822  -33.45412 1.000 33.55954  ? 5   MAN H H1     1 
HETATM 4830 H  H2     . MAN H 5  .   ? -21.92661 24.12746  -31.32073 1.000 34.48328  ? 5   MAN H H2     1 
HETATM 4831 H  H3     . MAN H 5  .   ? -24.10552 23.15985  -30.88102 1.000 38.38726  ? 5   MAN H H3     1 
HETATM 4832 H  H4     . MAN H 5  .   ? -25.08381 24.44713  -33.45509 1.000 42.62046  ? 5   MAN H H4     1 
HETATM 4833 H  H5     . MAN H 5  .   ? -24.72389 21.48453  -32.80281 1.000 38.49745  ? 5   MAN H H5     1 
HETATM 4834 H  H61    . MAN H 5  .   ? -26.57623 22.28633  -34.42398 1.000 45.68224  ? 5   MAN H H61    1 
HETATM 4835 H  H62    . MAN H 5  .   ? -25.41187 21.06646  -35.01411 1.000 45.68224  ? 5   MAN H H62    1 
HETATM 4836 H  HO2    . MAN H 5  .   ? -23.19379 25.76784  -32.70496 1.000 40.03971  ? 5   MAN H HO2    1 
HETATM 4837 H  HO3    . MAN H 5  .   ? -25.22568 25.50992  -31.49946 1.000 39.35745  ? 5   MAN H HO3    1 
HETATM 4838 H  HO4    . MAN H 5  .   ? -26.33637 22.64988  -31.57993 1.000 48.82721  ? 5   MAN H HO4    1 
HETATM 4839 H  HO6    . MAN H 5  .   ? -24.32429 23.52297  -35.39053 1.000 47.49018  ? 5   MAN H HO6    1 
HETATM 4840 C  C1     . FUC H 5  .   ? -15.54677 19.89269  -24.50722 1.000 60.23646  ? 6   FUC H C1     1 
HETATM 4841 C  C2     . FUC H 5  .   ? -16.68494 19.13768  -23.79771 1.000 64.99249  ? 6   FUC H C2     1 
HETATM 4842 C  C3     . FUC H 5  .   ? -16.11349 18.40601  -22.57089 1.000 73.94018  ? 6   FUC H C3     1 
HETATM 4843 C  C4     . FUC H 5  .   ? -15.38802 19.42343  -21.65184 1.000 85.34692  ? 6   FUC H C4     1 
HETATM 4844 C  C5     . FUC H 5  .   ? -14.31919 20.18790  -22.45579 1.000 80.82817  ? 6   FUC H C5     1 
HETATM 4845 C  C6     . FUC H 5  .   ? -13.65253 21.33683  -21.70189 1.000 90.53028  ? 6   FUC H C6     1 
HETATM 4846 O  O2     . FUC H 5  .   ? -17.37353 18.24702  -24.67345 1.000 55.01876  ? 6   FUC H O2     1 
HETATM 4847 O  O3     . FUC H 5  .   ? -17.15349 17.77458  -21.81778 1.000 73.10685  ? 6   FUC H O3     1 
HETATM 4848 O  O4     . FUC H 5  .   ? -16.31975 20.33370  -21.09201 1.000 100.12692 ? 6   FUC H O4     1 
HETATM 4849 O  O5     . FUC H 5  .   ? -14.88136 20.78200  -23.64274 1.000 78.70964  ? 6   FUC H O5     1 
HETATM 4850 H  H1     . FUC H 5  .   ? -15.93920 20.51782  -25.31877 1.000 72.31141  ? 6   FUC H H1     1 
HETATM 4851 H  H2     . FUC H 5  .   ? -17.43576 19.85639  -23.45630 1.000 78.01865  ? 6   FUC H H2     1 
HETATM 4852 H  H3     . FUC H 5  .   ? -15.39595 17.64179  -22.90750 1.000 88.75588  ? 6   FUC H H3     1 
HETATM 4853 H  H4     . FUC H 5  .   ? -14.87068 18.86835  -20.84993 1.000 102.44396 ? 6   FUC H H4     1 
HETATM 4854 H  H5     . FUC H 5  .   ? -13.55774 19.44282  -22.72974 1.000 97.02147  ? 6   FUC H H5     1 
HETATM 4855 H  H61    . FUC H 5  .   ? -14.25517 22.24552  -21.79102 1.000 108.66399 ? 6   FUC H H61    1 
HETATM 4856 H  H62    . FUC H 5  .   ? -12.65820 21.53124  -22.11465 1.000 108.66399 ? 6   FUC H H62    1 
HETATM 4857 H  H63    . FUC H 5  .   ? -13.55119 21.08339  -20.64249 1.000 108.66399 ? 6   FUC H H63    1 
HETATM 4858 H  HO2    . FUC H 5  .   ? -16.69352 17.86776  -25.24292 1.000 66.05017  ? 6   FUC H HO2    1 
HETATM 4859 H  HO3    . FUC H 5  .   ? -17.59622 18.48179  -21.34093 1.000 87.75588  ? 6   FUC H HO3    1 
HETATM 4860 H  HO4    . FUC H 5  .   ? -16.41233 21.04077  -21.75034 1.000 120.17996 ? 6   FUC H HO4    1 
HETATM 4861 MN MN     . MN  I 6  .   ? 21.55324  -2.27219  37.20572  1.000 30.07507  ? 401 MN  A MN     1 
HETATM 4862 N  N1     . UDP J 7  .   ? 22.55675  2.89521   31.47968  1.000 33.60328  ? 402 UDP A N1     1 
HETATM 4863 C  C2     . UDP J 7  .   ? 22.18792  3.75071   30.43936  1.000 30.78193  ? 402 UDP A C2     1 
HETATM 4864 N  N3     . UDP J 7  .   ? 23.23955  4.30581   29.74376  1.000 37.38045  ? 402 UDP A N3     1 
HETATM 4865 C  C4     . UDP J 7  .   ? 24.58830  4.10431   29.98732  1.000 36.33354  ? 402 UDP A C4     1 
HETATM 4866 C  C5     . UDP J 7  .   ? 24.88198  3.21889   31.07365  1.000 31.72351  ? 402 UDP A C5     1 
HETATM 4867 C  C6     . UDP J 7  .   ? 23.88040  2.65429   31.77133  1.000 37.58693  ? 402 UDP A C6     1 
HETATM 4868 O  O2     . UDP J 7  .   ? 21.02436  3.99802   30.15447  1.000 31.58360  ? 402 UDP A O2     1 
HETATM 4869 O  O4     . UDP J 7  .   ? 25.43018  4.67499   29.27793  1.000 40.65287  ? 402 UDP A O4     1 
HETATM 4870 C  "C1'"  . UDP J 7  .   ? 21.49485  2.25478   32.26820  1.000 25.88565  ? 402 UDP A "C1'"  1 
HETATM 4871 C  "C2'"  . UDP J 7  .   ? 21.66451  0.73927   32.38473  1.000 29.02301  ? 402 UDP A "C2'"  1 
HETATM 4872 O  "O2'"  . UDP J 7  .   ? 21.09051  0.02155   31.30161  1.000 34.89733  ? 402 UDP A "O2'"  1 
HETATM 4873 C  "C3'"  . UDP J 7  .   ? 20.89112  0.46938   33.67744  1.000 31.34197  ? 402 UDP A "C3'"  1 
HETATM 4874 C  "C4'"  . UDP J 7  .   ? 21.23722  1.69152   34.53265  1.000 33.16462  ? 402 UDP A "C4'"  1 
HETATM 4875 O  "O4'"  . UDP J 7  .   ? 21.56793  2.74819   33.59562  1.000 31.49782  ? 402 UDP A "O4'"  1 
HETATM 4876 O  "O3'"  . UDP J 7  .   ? 19.49741  0.40011   33.41016  1.000 27.63596  ? 402 UDP A "O3'"  1 
HETATM 4877 C  "C5'"  . UDP J 7  .   ? 22.39044  1.48684   35.48329  1.000 32.52963  ? 402 UDP A "C5'"  1 
HETATM 4878 O  "O5'"  . UDP J 7  .   ? 23.45576  0.80958   34.78454  1.000 36.08248  ? 402 UDP A "O5'"  1 
HETATM 4879 P  PA     . UDP J 7  .   ? 24.01242  -0.58284  35.29935  1.000 42.19378  ? 402 UDP A PA     1 
HETATM 4880 O  O1A    . UDP J 7  .   ? 25.07199  -1.00721  34.35350  1.000 40.73216  ? 402 UDP A O1A    1 
HETATM 4881 O  O2A    . UDP J 7  .   ? 22.86168  -1.57400  35.52285  1.000 32.61798  ? 402 UDP A O2A    1 
HETATM 4882 O  O3A    . UDP J 7  .   ? 24.63948  -0.25220  36.73746  1.000 44.50973  ? 402 UDP A O3A    1 
HETATM 4883 P  PB     . UDP J 7  .   ? 24.57621  -1.18310  38.01947  1.000 52.98049  ? 402 UDP A PB     1 
HETATM 4884 O  O1B    . UDP J 7  .   ? 25.50365  -2.34345  37.64873  1.000 56.71554  ? 402 UDP A O1B    1 
HETATM 4885 O  O2B    . UDP J 7  .   ? 25.24822  -0.33186  39.10500  1.000 43.09184  ? 402 UDP A O2B    1 
HETATM 4886 O  O3B    . UDP J 7  .   ? 23.15628  -1.63840  38.32593  1.000 34.62645  ? 402 UDP A O3B    1 
HETATM 4887 H  HN3    . UDP J 7  .   ? 23.03742  4.83604   29.09951  1.000 44.88420  ? 402 UDP A HN3    1 
HETATM 4888 H  H5     . UDP J 7  .   ? 25.76632  3.03536   31.29538  1.000 38.09587  ? 402 UDP A H5     1 
HETATM 4889 H  H6     . UDP J 7  .   ? 24.09025  2.08227   32.47394  1.000 45.13197  ? 402 UDP A H6     1 
HETATM 4890 H  "H1'"  . UDP J 7  .   ? 20.62969  2.46530   31.88338  1.000 31.09044  ? 402 UDP A "H1'"  1 
HETATM 4891 H  "H2'"  . UDP J 7  .   ? 22.60984  0.53390   32.45590  1.000 34.85527  ? 402 UDP A "H2'"  1 
HETATM 4892 H  "HO2'" . UDP J 7  .   ? 20.33993  0.36983   31.10488  1.000 41.90445  ? 402 UDP A "HO2'" 1 
HETATM 4893 H  "H3'"  . UDP J 7  .   ? 21.20664  -0.33428  34.11957  1.000 37.63802  ? 402 UDP A "H3'"  1 
HETATM 4894 H  "H4'"  . UDP J 7  .   ? 20.44668  1.96083   35.02603  1.000 39.82520  ? 402 UDP A "H4'"  1 
HETATM 4895 H  "HO3'" . UDP J 7  .   ? 19.35452  -0.11475  32.75029  1.000 33.19081  ? 402 UDP A "HO3'" 1 
HETATM 4896 H  "H5'1" . UDP J 7  .   ? 22.70748  2.34590   35.80330  1.000 39.06321  ? 402 UDP A "H5'1" 1 
HETATM 4897 H  "H5'2" . UDP J 7  .   ? 22.10239  0.94742   36.23625  1.000 39.06321  ? 402 UDP A "H5'2" 1 
HETATM 4898 C  C1     . B3P K 8  .   ? 23.85971  20.98969  53.18583  1.000 19.07427  ? 403 B3P A C1     1 
HETATM 4899 C  C2     . B3P K 8  .   ? 23.56644  19.47080  53.07946  1.000 18.79412  ? 403 B3P A C2     1 
HETATM 4900 C  C3     . B3P K 8  .   ? 23.30481  21.83555  52.00563  1.000 22.96418  ? 403 B3P A C3     1 
HETATM 4901 N  N1     . B3P K 8  .   ? 21.83504  21.91389  52.08503  1.000 20.01552  ? 403 B3P A N1     1 
HETATM 4902 C  C4     . B3P K 8  .   ? 21.24981  22.77219  51.03508  1.000 21.75154  ? 403 B3P A C4     1 
HETATM 4903 C  C5     . B3P K 8  .   ? 21.67017  24.25742  51.22623  1.000 22.16110  ? 403 B3P A C5     1 
HETATM 4904 C  C6     . B3P K 8  .   ? 19.73158  22.59858  51.15821  1.000 25.72675  ? 403 B3P A C6     1 
HETATM 4905 C  C7     . B3P K 8  .   ? 21.72705  22.37609  49.63422  1.000 21.13400  ? 403 B3P A C7     1 
HETATM 4906 N  N2     . B3P K 8  .   ? 22.12868  19.22102  53.24899  1.000 17.10280  ? 403 B3P A N2     1 
HETATM 4907 C  C8     . B3P K 8  .   ? 21.66534  17.87498  52.84319  1.000 19.19484  ? 403 B3P A C8     1 
HETATM 4908 C  C9     . B3P K 8  .   ? 20.29869  17.73322  53.55163  1.000 22.30080  ? 403 B3P A C9     1 
HETATM 4909 C  C10    . B3P K 8  .   ? 22.63979  16.77720  53.31758  1.000 19.19661  ? 403 B3P A C10    1 
HETATM 4910 C  C11    . B3P K 8  .   ? 21.48309  17.84036  51.33612  1.000 16.99776  ? 403 B3P A C11    1 
HETATM 4911 O  O1     . B3P K 8  .   ? 19.69264  16.48100  53.27766  1.000 21.44128  ? 403 B3P A O1     1 
HETATM 4912 O  O2     . B3P K 8  .   ? 22.80189  16.86834  54.71492  1.000 19.40639  ? 403 B3P A O2     1 
HETATM 4913 O  O3     . B3P K 8  .   ? 20.68561  18.95337  50.99012  1.000 20.68371  ? 403 B3P A O3     1 
HETATM 4914 O  O4     . B3P K 8  .   ? 21.39386  24.71322  52.53314  1.000 20.66258  ? 403 B3P A O4     1 
HETATM 4915 O  O5     . B3P K 8  .   ? 19.04729  23.45180  50.27645  1.000 21.24256  ? 403 B3P A O5     1 
HETATM 4916 O  O6     . B3P K 8  .   ? 21.39973  21.04718  49.31572  1.000 25.10413  ? 403 B3P A O6     1 
HETATM 4917 H  H11    . B3P K 8  .   ? 24.82104  21.11321  53.22448  1.000 22.91678  ? 403 B3P A H11    1 
HETATM 4918 H  H12    . B3P K 8  .   ? 23.46701  21.31970  54.00910  1.000 22.91678  ? 403 B3P A H12    1 
HETATM 4919 H  H21    . B3P K 8  .   ? 24.05812  18.99916  53.76991  1.000 22.58061  ? 403 B3P A H21    1 
HETATM 4920 H  H22    . B3P K 8  .   ? 23.84801  19.14905  52.20877  1.000 22.58061  ? 403 B3P A H22    1 
HETATM 4921 H  H31    . B3P K 8  .   ? 23.67715  22.73022  52.04845  1.000 27.58467  ? 403 B3P A H31    1 
HETATM 4922 H  H32    . B3P K 8  .   ? 23.55976  21.42203  51.16605  1.000 27.58467  ? 403 B3P A H32    1 
HETATM 4923 H  HN1    . B3P K 8  .   ? 21.61863  22.25859  52.87652  1.000 24.04628  ? 403 B3P A HN1    1 
HETATM 4924 H  H51    . B3P K 8  .   ? 22.62263  24.33762  51.06104  1.000 26.62098  ? 403 B3P A H51    1 
HETATM 4925 H  H52    . B3P K 8  .   ? 21.18116  24.80583  50.59298  1.000 26.62098  ? 403 B3P A H52    1 
HETATM 4926 H  H61    . B3P K 8  .   ? 19.46368  22.80439  52.06748  1.000 30.89976  ? 403 B3P A H61    1 
HETATM 4927 H  H62    . B3P K 8  .   ? 19.50164  21.67960  50.94964  1.000 30.89976  ? 403 B3P A H62    1 
HETATM 4928 H  H71    . B3P K 8  .   ? 21.30902  22.96360  48.98538  1.000 25.38846  ? 403 B3P A H71    1 
HETATM 4929 H  H72    . B3P K 8  .   ? 22.69089  22.47746  49.59362  1.000 25.38846  ? 403 B3P A H72    1 
HETATM 4930 H  HN2    . B3P K 8  .   ? 21.94977  19.30753  54.11652  1.000 20.55102  ? 403 B3P A HN2    1 
HETATM 4931 H  H91    . B3P K 8  .   ? 19.71068  18.44011  53.24268  1.000 26.78862  ? 403 B3P A H91    1 
HETATM 4932 H  H92    . B3P K 8  .   ? 20.43207  17.81391  54.50902  1.000 26.78862  ? 403 B3P A H92    1 
HETATM 4933 H  H101   . B3P K 8  .   ? 22.27957  15.90569  53.09041  1.000 23.06359  ? 403 B3P A H101   1 
HETATM 4934 H  H102   . B3P K 8  .   ? 23.49899  16.89898  52.88416  1.000 23.06359  ? 403 B3P A H102   1 
HETATM 4935 H  H111   . B3P K 8  .   ? 22.34544  17.90001  50.89600  1.000 20.42497  ? 403 B3P A H111   1 
HETATM 4936 H  H112   . B3P K 8  .   ? 21.03847  17.01899  51.07429  1.000 20.42497  ? 403 B3P A H112   1 
HETATM 4937 H  HO1    . B3P K 8  .   ? 19.97588  15.91000  53.84131  1.000 25.75719  ? 403 B3P A HO1    1 
HETATM 4938 H  HO2    . B3P K 8  .   ? 23.43276  16.35430  54.96034  1.000 23.31533  ? 403 B3P A HO2    1 
HETATM 4939 H  HO3    . B3P K 8  .   ? 19.94360  18.68299  50.67058  1.000 24.84812  ? 403 B3P A HO3    1 
HETATM 4940 H  HO4    . B3P K 8  .   ? 20.57177  24.90361  52.60260  1.000 24.82275  ? 403 B3P A HO4    1 
HETATM 4941 H  HO5    . B3P K 8  .   ? 18.74289  24.11780  50.71154  1.000 25.51874  ? 403 B3P A HO5    1 
HETATM 4942 H  HO6    . B3P K 8  .   ? 22.03070  20.53186  49.55776  1.000 30.15261  ? 403 B3P A HO6    1 
HETATM 4943 MN MN     . MN  L 6  .   ? 6.55451   6.46733   0.65623   1.000 50.00140  ? 401 MN  B MN     1 
HETATM 4944 N  N1     . UDP M 7  .   ? 12.07797  11.65887  0.80352   1.000 66.99840  ? 402 UDP B N1     1 
HETATM 4945 C  C2     . UDP M 7  .   ? 13.18751  12.32815  0.31056   1.000 67.71007  ? 402 UDP B C2     1 
HETATM 4946 N  N3     . UDP M 7  .   ? 14.01504  12.86735  1.26761   1.000 68.30186  ? 402 UDP B N3     1 
HETATM 4947 C  C4     . UDP M 7  .   ? 13.84436  12.80337  2.63892   1.000 69.34581  ? 402 UDP B C4     1 
HETATM 4948 C  C5     . UDP M 7  .   ? 12.67563  12.09424  3.06827   1.000 67.11912  ? 402 UDP B C5     1 
HETATM 4949 C  C6     . UDP M 7  .   ? 11.84552  11.55461  2.15645   1.000 66.66529  ? 402 UDP B C6     1 
HETATM 4950 O  O2     . UDP M 7  .   ? 13.42208  12.43920  -0.88594  1.000 63.61809  ? 402 UDP B O2     1 
HETATM 4951 O  O4     . UDP M 7  .   ? 14.67974  13.33915  3.38590   1.000 60.36305  ? 402 UDP B O4     1 
HETATM 4952 C  "C1'"  . UDP M 7  .   ? 11.15572  11.05043  -0.17038  1.000 66.02262  ? 402 UDP B "C1'"  1 
HETATM 4953 C  "C2'"  . UDP M 7  .   ? 10.98901  9.53868   0.01983   1.000 65.70480  ? 402 UDP B "C2'"  1 
HETATM 4954 O  "O2'"  . UDP M 7  .   ? 11.91389  8.79847   -0.77057  1.000 60.77284  ? 402 UDP B "O2'"  1 
HETATM 4955 C  "C3'"  . UDP M 7  .   ? 9.54584   9.34125   -0.44502  1.000 62.86546  ? 402 UDP B "C3'"  1 
HETATM 4956 C  "C4'"  . UDP M 7  .   ? 8.86502   10.59891  0.08751   1.000 61.68429  ? 402 UDP B "C4'"  1 
HETATM 4957 O  "O4'"  . UDP M 7  .   ? 9.87222   11.63128  0.00676   1.000 60.32039  ? 402 UDP B "O4'"  1 
HETATM 4958 O  "O3'"  . UDP M 7  .   ? 9.46720   9.25929   -1.86529  1.000 57.09236  ? 402 UDP B "O3'"  1 
HETATM 4959 C  "C5'"  . UDP M 7  .   ? 8.37468   10.50507  1.51043   1.000 59.81481  ? 402 UDP B "C5'"  1 
HETATM 4960 O  "O5'"  . UDP M 7  .   ? 7.91225   9.16227   1.75879   1.000 71.88442  ? 402 UDP B "O5'"  1 
HETATM 4961 P  PA     . UDP M 7  .   ? 8.68049   8.19131   2.74569   1.000 66.87123  ? 402 UDP B PA     1 
HETATM 4962 O  O1A    . UDP M 7  .   ? 9.92103   8.88713   3.16324   1.000 75.20068  ? 402 UDP B O1A    1 
HETATM 4963 O  O2A    . UDP M 7  .   ? 8.84172   6.80232   2.13270   1.000 66.67261  ? 402 UDP B O2A    1 
HETATM 4964 O  O3A    . UDP M 7  .   ? 7.69026   8.02378   3.99221   1.000 74.78312  ? 402 UDP B O3A    1 
HETATM 4965 P  PB     . UDP M 7  .   ? 6.15942   7.61195   3.92639   1.000 72.52658  ? 402 UDP B PB     1 
HETATM 4966 O  O1B    . UDP M 7  .   ? 6.14815   6.22148   4.56640   1.000 71.57252  ? 402 UDP B O1B    1 
HETATM 4967 O  O2B    . UDP M 7  .   ? 5.47836   8.64234   4.85290   1.000 67.39796  ? 402 UDP B O2B    1 
HETATM 4968 O  O3B    . UDP M 7  .   ? 5.62894   7.61660   2.52638   1.000 66.04681  ? 402 UDP B O3B    1 
HETATM 4969 H  HN3    . UDP M 7  .   ? 14.71032  13.28504  0.98396   1.000 81.98989  ? 402 UDP B HN3    1 
HETATM 4970 H  H5     . UDP M 7  .   ? 12.49254  12.00800  3.97598   1.000 80.57060  ? 402 UDP B H5     1 
HETATM 4971 H  H6     . UDP M 7  .   ? 11.09134  11.09705  2.45097   1.000 80.02601  ? 402 UDP B H6     1 
HETATM 4972 H  "H1'"  . UDP M 7  .   ? 11.46151  11.22797  -1.07363  1.000 79.25480  ? 402 UDP B "H1'"  1 
HETATM 4973 H  "H2'"  . UDP M 7  .   ? 11.09049  9.30750   0.95640   1.000 78.87342  ? 402 UDP B "H2'"  1 
HETATM 4974 H  "HO2'" . UDP M 7  .   ? 12.70176  9.07232   -0.60972  1.000 72.95507  ? 402 UDP B "HO2'" 1 
HETATM 4975 H  "H3'"  . UDP M 7  .   ? 9.15063   8.55446   -0.03801  1.000 75.46622  ? 402 UDP B "H3'"  1 
HETATM 4976 H  "H4'"  . UDP M 7  .   ? 8.12562   10.82643  -0.49766  1.000 74.04880  ? 402 UDP B "H4'"  1 
HETATM 4977 H  "HO3'" . UDP M 7  .   ? 10.24604  9.15232   -2.18741  1.000 68.53849  ? 402 UDP B "HO3'" 1 
HETATM 4978 H  "H5'1" . UDP M 7  .   ? 9.09873   10.71608  2.12045   1.000 71.80544  ? 402 UDP B "H5'1" 1 
HETATM 4979 H  "H5'2" . UDP M 7  .   ? 7.64471   11.12917  1.64663   1.000 71.80544  ? 402 UDP B "H5'2" 1 
HETATM 4980 C  C1     . B3P N 8  .   ? -8.92677  29.74355  6.49164   1.000 42.04070  ? 403 B3P B C1     1 
HETATM 4981 C  C2     . B3P N 8  .   ? -8.62011  28.28338  6.01417   1.000 41.40104  ? 403 B3P B C2     1 
HETATM 4982 C  C3     . B3P N 8  .   ? -8.63381  30.77031  5.35029   1.000 46.60779  ? 403 B3P B C3     1 
HETATM 4983 N  N1     . B3P N 8  .   ? -7.35608  30.44962  4.70399   1.000 47.96456  ? 403 B3P B N1     1 
HETATM 4984 C  C4     . B3P N 8  .   ? -7.00163  31.30853  3.54663   1.000 43.64719  ? 403 B3P B C4     1 
HETATM 4985 C  C5     . B3P N 8  .   ? -5.54630  30.96298  3.20093   1.000 47.70853  ? 403 B3P B C5     1 
HETATM 4986 C  C6     . B3P N 8  .   ? -7.03952  32.79770  3.90519   1.000 41.39355  ? 403 B3P B C6     1 
HETATM 4987 C  C7     . B3P N 8  .   ? -7.85432  31.05402  2.30604   1.000 46.21743  ? 403 B3P B C7     1 
HETATM 4988 N  N2     . B3P N 8  .   ? -9.55897  27.97421  4.91099   1.000 43.38278  ? 403 B3P B N2     1 
HETATM 4989 C  C8     . B3P N 8  .   ? -9.10287  26.81915  4.09325   1.000 41.46624  ? 403 B3P B C8     1 
HETATM 4990 C  C9     . B3P N 8  .   ? -9.00182  25.58009  4.99789   1.000 35.78576  ? 403 B3P B C9     1 
HETATM 4991 C  C10    . B3P N 8  .   ? -10.16695 26.51384  3.03617   1.000 39.11767  ? 403 B3P B C10    1 
HETATM 4992 C  C11    . B3P N 8  .   ? -7.79807  27.26100  3.41417   1.000 38.94971  ? 403 B3P B C11    1 
HETATM 4993 O  O1     . B3P N 8  .   ? -10.21073 25.55424  5.73009   1.000 37.89666  ? 403 B3P B O1     1 
HETATM 4994 O  O2     . B3P N 8  .   ? -9.89417  25.26625  2.43216   1.000 40.09474  ? 403 B3P B O2     1 
HETATM 4995 O  O3     . B3P N 8  .   ? -7.10348  26.14289  2.95378   1.000 56.58008  ? 403 B3P B O3     1 
HETATM 4996 O  O4     . B3P N 8  .   ? -5.42807  29.56925  3.06965   1.000 40.64196  ? 403 B3P B O4     1 
HETATM 4997 O  O5     . B3P N 8  .   ? -8.32275  33.32404  3.70751   1.000 41.93281  ? 403 B3P B O5     1 
HETATM 4998 O  O6     . B3P N 8  .   ? -7.34667  31.92475  1.31462   1.000 42.77664  ? 403 B3P B O6     1 
HETATM 4999 H  H11    . B3P N 8  .   ? -8.37363  29.95243  7.26061   1.000 50.47650  ? 403 B3P B H11    1 
HETATM 5000 H  H12    . B3P N 8  .   ? -9.85984  29.80764  6.74888   1.000 50.47650  ? 403 B3P B H12    1 
HETATM 5001 H  H21    . B3P N 8  .   ? -8.74992  27.65986  6.74579   1.000 49.70891  ? 403 B3P B H21    1 
HETATM 5002 H  H22    . B3P N 8  .   ? -7.70484  28.22167  5.69892   1.000 49.70891  ? 403 B3P B H22    1 
HETATM 5003 H  H31    . B3P N 8  .   ? -9.34581  30.73264  4.69261   1.000 55.95700  ? 403 B3P B H31    1 
HETATM 5004 H  H32    . B3P N 8  .   ? -8.59004  31.66413  5.72455   1.000 55.95700  ? 403 B3P B H32    1 
HETATM 5005 H  HN1    . B3P N 8  .   ? -6.71840  30.55719  5.31546   1.000 57.58513  ? 403 B3P B HN1    1 
HETATM 5006 H  H51    . B3P N 8  .   ? -5.30099  31.38968  2.36507   1.000 57.27790  ? 403 B3P B H51    1 
HETATM 5007 H  H52    . B3P N 8  .   ? -4.96168  31.27293  3.91019   1.000 57.27790  ? 403 B3P B H52    1 
HETATM 5008 H  H61    . B3P N 8  .   ? -6.41043  33.27551  3.34230   1.000 49.69991  ? 403 B3P B H61    1 
HETATM 5009 H  H62    . B3P N 8  .   ? -6.79225  32.90594  4.83688   1.000 49.69991  ? 403 B3P B H62    1 
HETATM 5010 H  H71    . B3P N 8  .   ? -7.76949  30.13077  2.02092   1.000 55.48857  ? 403 B3P B H71    1 
HETATM 5011 H  H72    . B3P N 8  .   ? -8.78546  31.25549  2.48849   1.000 55.48857  ? 403 B3P B H72    1 
HETATM 5012 H  HN2    . B3P N 8  .   ? -9.61468  28.68773  4.38194   1.000 52.08700  ? 403 B3P B HN2    1 
HETATM 5013 H  H91    . B3P N 8  .   ? -8.24384  25.65936  5.59795   1.000 42.97057  ? 403 B3P B H91    1 
HETATM 5014 H  H92    . B3P N 8  .   ? -8.91252  24.77601  4.46274   1.000 42.97057  ? 403 B3P B H92    1 
HETATM 5015 H  H101   . B3P N 8  .   ? -11.03972 26.48276  3.45831   1.000 46.96886  ? 403 B3P B H101   1 
HETATM 5016 H  H102   . B3P N 8  .   ? -10.15580 27.20825  2.35900   1.000 46.96886  ? 403 B3P B H102   1 
HETATM 5017 H  H111   . B3P N 8  .   ? -8.00638  27.84077  2.66493   1.000 46.76731  ? 403 B3P B H111   1 
HETATM 5018 H  H112   . B3P N 8  .   ? -7.24865  27.73920  4.05477   1.000 46.76731  ? 403 B3P B H112   1 
HETATM 5019 H  HO1    . B3P N 8  .   ? -10.03329 25.46513  6.55600   1.000 45.50365  ? 403 B3P B HO1    1 
HETATM 5020 H  HO2    . B3P N 8  .   ? -10.50211 24.71119  2.63526   1.000 48.14135  ? 403 B3P B HO2    1 
HETATM 5021 H  HO3    . B3P N 8  .   ? -6.45685  25.97075  3.47440   1.000 67.92376  ? 403 B3P B HO3    1 
HETATM 5022 H  HO4    . B3P N 8  .   ? -5.34593  29.36816  2.24699   1.000 48.79802  ? 403 B3P B HO4    1 
HETATM 5023 H  HO5    . B3P N 8  .   ? -8.27257  33.97948  3.16604   1.000 50.34703  ? 403 B3P B HO5    1 
HETATM 5024 H  HO6    . B3P N 8  .   ? -7.94909  32.48776  1.09768   1.000 51.35962  ? 403 B3P B HO6    1 
HETATM 5025 C  C1     . NAG O 9  .   ? 3.00775   35.60452  -12.25729 1.000 134.15838 ? 404 NAG B C1     1 
HETATM 5026 C  C2     . NAG O 9  .   ? 1.73574   36.43904  -12.04281 1.000 145.24045 ? 404 NAG B C2     1 
HETATM 5027 C  C3     . NAG O 9  .   ? 1.95371   37.85831  -12.57125 1.000 151.04786 ? 404 NAG B C3     1 
HETATM 5028 C  C4     . NAG O 9  .   ? 3.21734   38.46767  -11.97392 1.000 154.92133 ? 404 NAG B C4     1 
HETATM 5029 C  C5     . NAG O 9  .   ? 4.41144   37.53388  -12.15746 1.000 145.04523 ? 404 NAG B C5     1 
HETATM 5030 C  C6     . NAG O 9  .   ? 5.65731   38.02264  -11.45604 1.000 138.99827 ? 404 NAG B C6     1 
HETATM 5031 C  C7     . NAG O 9  .   ? -0.68443  36.14799  -12.37861 1.000 139.43558 ? 404 NAG B C7     1 
HETATM 5032 C  C8     . NAG O 9  .   ? -1.75038  35.42083  -13.14416 1.000 134.82618 ? 404 NAG B C8     1 
HETATM 5033 N  N2     . NAG O 9  .   ? 0.58033   35.82847  -12.68420 1.000 142.14538 ? 404 NAG B N2     1 
HETATM 5034 O  O3     . NAG O 9  .   ? 0.82855   38.67219  -12.25786 1.000 156.00566 ? 404 NAG B O3     1 
HETATM 5035 O  O4     . NAG O 9  .   ? 3.51042   39.70737  -12.60948 1.000 153.95064 ? 404 NAG B O4     1 
HETATM 5036 O  O5     . NAG O 9  .   ? 4.11207   36.24161  -11.61218 1.000 136.83210 ? 404 NAG B O5     1 
HETATM 5037 O  O6     . NAG O 9  .   ? 6.54252   38.66368  -12.36344 1.000 124.95534 ? 404 NAG B O6     1 
HETATM 5038 O  O7     . NAG O 9  .   ? -0.95645  36.98683  -11.52351 1.000 136.02003 ? 404 NAG B O7     1 
HETATM 5039 H  H1     . NAG O 9  .   ? 3.18976   35.53365  -13.21355 1.000 161.01772 ? 404 NAG B H1     1 
HETATM 5040 H  H2     . NAG O 9  .   ? 1.56058   36.48692  -11.08385 1.000 174.31620 ? 404 NAG B H2     1 
HETATM 5041 H  H3     . NAG O 9  .   ? 2.04977   37.81398  -13.54150 1.000 181.28509 ? 404 NAG B H3     1 
HETATM 5042 H  H4     . NAG O 9  .   ? 3.06749   38.61244  -11.02042 1.000 185.93325 ? 404 NAG B H4     1 
HETATM 5043 H  H5     . NAG O 9  .   ? 4.59532   37.44053  -13.11142 1.000 174.08194 ? 404 NAG B H5     1 
HETATM 5044 H  H61    . NAG O 9  .   ? 6.11353   37.26222  -11.04836 1.000 166.82559 ? 404 NAG B H61    1 
HETATM 5045 H  H62    . NAG O 9  .   ? 5.40329   38.65497  -10.75732 1.000 166.82559 ? 404 NAG B H62    1 
HETATM 5046 H  H81    . NAG O 9  .   ? -1.53763  34.46876  -13.17362 1.000 161.81907 ? 404 NAG B H81    1 
HETATM 5047 H  H82    . NAG O 9  .   ? -1.79509  35.77250  -14.05350 1.000 161.81907 ? 404 NAG B H82    1 
HETATM 5048 H  H83    . NAG O 9  .   ? -2.61178  35.54824  -12.70333 1.000 161.81907 ? 404 NAG B H83    1 
HETATM 5049 H  HN2    . NAG O 9  .   ? 0.72467   35.19690  -13.32610 1.000 170.60211 ? 404 NAG B HN2    1 
HETATM 5050 H  HO3    . NAG O 9  .   ? 0.65683   38.62351  -11.38782 1.000 187.23445 ? 404 NAG B HO3    1 
HETATM 5051 H  HO4    . NAG O 9  .   ? 3.84278   39.55258  -13.41833 1.000 184.76843 ? 404 NAG B HO4    1 
HETATM 5052 H  HO6    . NAG O 9  .   ? 6.06883   39.11272  -12.96499 1.000 149.97407 ? 404 NAG B HO6    1 
HETATM 5053 O  O      . HOH P 10 .   ? 38.74937  4.39953   44.67850  1.000 35.67968  ? 501 HOH A O      1 
HETATM 5054 O  O      . HOH P 10 .   ? 1.622     -28.589   40.477    1.000 39.63128  ? 502 HOH A O      1 
HETATM 5055 O  O      . HOH P 10 .   ? 17.37824  17.17349  22.38299  1.000 40.44748  ? 503 HOH A O      1 
HETATM 5056 O  O      . HOH P 10 .   ? 24.18490  14.72860  33.49321  1.000 38.83922  ? 504 HOH A O      1 
HETATM 5057 O  O      . HOH P 10 .   ? 17.78590  3.05896   35.77065  1.000 37.44215  ? 505 HOH A O      1 
HETATM 5058 O  O      . HOH P 10 .   ? -8.168    1.879     48.382    1.000 40.40878  ? 506 HOH A O      1 
HETATM 5059 O  O      . HOH P 10 .   ? 32.00741  16.24381  53.57204  1.000 31.89633  ? 507 HOH A O      1 
HETATM 5060 O  O      . HOH P 10 .   ? 33.88433  19.32369  40.21126  1.000 42.64701  ? 508 HOH A O      1 
HETATM 5061 O  O      . HOH P 10 .   ? 27.79612  14.32186  34.47944  1.000 41.40220  ? 509 HOH A O      1 
HETATM 5062 O  O      . HOH P 10 .   ? 1.85855   -25.08920 44.43687  1.000 49.97332  ? 510 HOH A O      1 
HETATM 5063 O  O      . HOH P 10 .   ? -1.23340  12.35493  37.57662  1.000 34.74622  ? 511 HOH A O      1 
HETATM 5064 O  O      . HOH P 10 .   ? 13.65164  23.95457  36.75118  1.000 37.74656  ? 512 HOH A O      1 
HETATM 5065 O  O      . HOH P 10 .   ? 6.62068   -0.41788  25.23725  1.000 34.31378  ? 513 HOH A O      1 
HETATM 5066 O  O      . HOH P 10 .   ? 2.95312   -7.04142  31.20175  1.000 33.50408  ? 514 HOH A O      1 
HETATM 5067 O  O      . HOH P 10 .   ? 24.68831  -1.14169  31.83484  1.000 44.61758  ? 515 HOH A O      1 
HETATM 5068 O  O      . HOH P 10 .   ? 26.73348  3.92759   27.21340  1.000 45.94551  ? 516 HOH A O      1 
HETATM 5069 O  O      . HOH P 10 .   ? 18.48379  -8.15690  48.53643  1.000 30.76201  ? 517 HOH A O      1 
HETATM 5070 O  O      . HOH P 10 .   ? 23.29452  -3.56884  33.94426  1.000 41.29209  ? 518 HOH A O      1 
HETATM 5071 O  O      . HOH P 10 .   ? 11.87197  3.52516   56.07999  1.000 36.30632  ? 519 HOH A O      1 
HETATM 5072 O  O      . HOH P 10 .   ? 28.41985  8.52295   46.29637  1.000 19.32097  ? 520 HOH A O      1 
HETATM 5073 O  O      . HOH P 10 .   ? 23.46857  2.01208   38.46880  1.000 45.01976  ? 521 HOH A O      1 
HETATM 5074 O  O      . HOH P 10 .   ? 30.67465  11.75201  54.84225  1.000 31.37957  ? 522 HOH A O      1 
HETATM 5075 O  O      . HOH P 10 .   ? 26.65374  20.69249  41.83967  1.000 29.75063  ? 523 HOH A O      1 
HETATM 5076 O  O      . HOH P 10 .   ? 24.52312  11.90947  35.51654  1.000 29.31887  ? 524 HOH A O      1 
HETATM 5077 O  O      . HOH P 10 .   ? 21.635    15.173    56.311    1.000 33.59247  ? 525 HOH A O      1 
HETATM 5078 O  O      . HOH P 10 .   ? 0.05276   -26.07136 38.12588  1.000 45.84098  ? 526 HOH A O      1 
HETATM 5079 O  O      . HOH P 10 .   ? 20.68489  5.33513   38.74297  1.000 29.88836  ? 527 HOH A O      1 
HETATM 5080 O  O      . HOH P 10 .   ? 5.59279   10.01180  49.50628  1.000 34.01314  ? 528 HOH A O      1 
HETATM 5081 O  O      . HOH P 10 .   ? 14.22120  -11.57203 23.79914  1.000 37.25084  ? 529 HOH A O      1 
HETATM 5082 O  O      . HOH P 10 .   ? 18.76917  7.64962   34.57149  1.000 20.04156  ? 530 HOH A O      1 
HETATM 5083 O  O      . HOH P 10 .   ? 19.44821  21.12245  47.55343  1.000 24.24486  ? 531 HOH A O      1 
HETATM 5084 O  O      . HOH P 10 .   ? 14.00652  2.51766   44.86993  1.000 19.71875  ? 532 HOH A O      1 
HETATM 5085 O  O      . HOH P 10 .   ? 21.02810  -6.63373  31.72449  1.000 34.47832  ? 533 HOH A O      1 
HETATM 5086 O  O      . HOH P 10 .   ? 31.59645  9.68980   53.12391  1.000 39.89965  ? 534 HOH A O      1 
HETATM 5087 O  O      . HOH P 10 .   ? 18.04222  -17.76937 39.91007  1.000 34.83060  ? 535 HOH A O      1 
HETATM 5088 O  O      . HOH P 10 .   ? 3.39879   -15.56967 47.36411  1.000 39.12834  ? 536 HOH A O      1 
HETATM 5089 O  O      . HOH P 10 .   ? -1.83093  9.76543   40.82244  1.000 31.65148  ? 537 HOH A O      1 
HETATM 5090 O  O      . HOH P 10 .   ? 15.20301  0.84407   53.18717  1.000 30.44034  ? 538 HOH A O      1 
HETATM 5091 O  O      . HOH P 10 .   ? 14.73841  13.72436  49.68977  1.000 19.46995  ? 539 HOH A O      1 
HETATM 5092 O  O      . HOH P 10 .   ? 6.92605   -3.01663  25.99334  1.000 32.03780  ? 540 HOH A O      1 
HETATM 5093 O  O      . HOH P 10 .   ? 23.05146  8.93900   18.13312  1.000 44.50297  ? 541 HOH A O      1 
HETATM 5094 O  O      . HOH P 10 .   ? 9.47834   -1.76662  53.39183  1.000 34.05327  ? 542 HOH A O      1 
HETATM 5095 O  O      . HOH P 10 .   ? 23.69030  -7.99655  46.53051  1.000 38.18843  ? 543 HOH A O      1 
HETATM 5096 O  O      . HOH P 10 .   ? 24.38524  -4.69775  37.08324  1.000 39.55336  ? 544 HOH A O      1 
HETATM 5097 O  O      . HOH P 10 .   ? 17.31693  -13.45395 41.12944  1.000 27.35827  ? 545 HOH A O      1 
HETATM 5098 O  O      . HOH P 10 .   ? 3.07094   15.64686  36.00440  1.000 39.27443  ? 546 HOH A O      1 
HETATM 5099 O  O      . HOH P 10 .   ? 13.29724  -17.46001 47.01345  1.000 32.06749  ? 547 HOH A O      1 
HETATM 5100 O  O      . HOH P 10 .   ? 0.68949   17.76934  43.64890  1.000 42.32201  ? 548 HOH A O      1 
HETATM 5101 O  O      . HOH P 10 .   ? 20.93194  1.90722   51.75458  1.000 31.00196  ? 549 HOH A O      1 
HETATM 5102 O  O      . HOH P 10 .   ? 22.97769  -6.66323  25.88532  1.000 44.00934  ? 550 HOH A O      1 
HETATM 5103 O  O      . HOH P 10 .   ? 15.45760  16.38417  54.11575  1.000 30.00752  ? 551 HOH A O      1 
HETATM 5104 O  O      . HOH P 10 .   ? 17.31805  19.90407  48.58670  1.000 23.62529  ? 552 HOH A O      1 
HETATM 5105 O  O      . HOH P 10 .   ? 12.49902  14.00585  51.02641  1.000 24.69119  ? 553 HOH A O      1 
HETATM 5106 O  O      . HOH P 10 .   ? 26.21147  6.29650   49.45520  1.000 30.26699  ? 554 HOH A O      1 
HETATM 5107 O  O      . HOH P 10 .   ? 18.47045  -7.69289  31.87839  1.000 28.84644  ? 555 HOH A O      1 
HETATM 5108 O  O      . HOH P 10 .   ? 35.80164  16.75268  40.81964  1.000 43.02269  ? 556 HOH A O      1 
HETATM 5109 O  O      . HOH P 10 .   ? 25.35977  1.60930   23.65975  1.000 45.57535  ? 557 HOH A O      1 
HETATM 5110 O  O      . HOH P 10 .   ? 5.11593   -7.57596  35.77648  1.000 28.34429  ? 558 HOH A O      1 
HETATM 5111 O  O      . HOH P 10 .   ? 0.05720   -8.03913  49.86918  1.000 46.99030  ? 559 HOH A O      1 
HETATM 5112 O  O      . HOH P 10 .   ? 14.56347  -0.97966  43.23428  1.000 21.59596  ? 560 HOH A O      1 
HETATM 5113 O  O      . HOH P 10 .   ? 22.91884  8.23139   30.02609  1.000 30.08800  ? 561 HOH A O      1 
HETATM 5114 O  O      . HOH P 10 .   ? 26.14415  18.42430  44.27047  1.000 27.81713  ? 562 HOH A O      1 
HETATM 5115 O  O      . HOH P 10 .   ? 6.72710   9.41216   54.70267  1.000 41.15513  ? 563 HOH A O      1 
HETATM 5116 O  O      . HOH P 10 .   ? 19.18273  -16.70066 38.53550  1.000 44.17251  ? 564 HOH A O      1 
HETATM 5117 O  O      . HOH P 10 .   ? 16.59429  22.42310  49.46262  1.000 30.30896  ? 565 HOH A O      1 
HETATM 5118 O  O      . HOH P 10 .   ? 20.89653  4.38139   54.21673  1.000 32.50727  ? 566 HOH A O      1 
HETATM 5119 O  O      . HOH P 10 .   ? 20.35028  9.25737   52.24557  1.000 23.51594  ? 567 HOH A O      1 
HETATM 5120 O  O      . HOH P 10 .   ? 16.21480  2.79677   27.56352  1.000 26.84106  ? 568 HOH A O      1 
HETATM 5121 O  O      . HOH P 10 .   ? 1.78953   -11.18465 42.02532  1.000 33.55561  ? 569 HOH A O      1 
HETATM 5122 O  O      . HOH P 10 .   ? 7.61684   -1.89730  50.79273  1.000 26.22028  ? 570 HOH A O      1 
HETATM 5123 O  O      . HOH P 10 .   ? 21.24979  -3.57230  32.16171  1.000 37.46632  ? 571 HOH A O      1 
HETATM 5124 O  O      . HOH P 10 .   ? 20.125    -17.179   33.179    1.000 32.93073  ? 572 HOH A O      1 
HETATM 5125 O  O      . HOH P 10 .   ? 9.27670   0.41969   50.17092  1.000 22.87697  ? 573 HOH A O      1 
HETATM 5126 O  O      . HOH P 10 .   ? 9.86767   6.02357   19.80541  1.000 35.26797  ? 574 HOH A O      1 
HETATM 5127 O  O      . HOH P 10 .   ? -6.21315  2.86649   33.26032  1.000 38.07560  ? 575 HOH A O      1 
HETATM 5128 O  O      . HOH P 10 .   ? 15.12466  17.15113  30.83675  1.000 35.66535  ? 576 HOH A O      1 
HETATM 5129 O  O      . HOH P 10 .   ? 20.31909  0.57482   47.52319  1.000 24.30853  ? 577 HOH A O      1 
HETATM 5130 O  O      . HOH P 10 .   ? 0.47831   -0.61049  50.26303  1.000 42.22721  ? 578 HOH A O      1 
HETATM 5131 O  O      . HOH P 10 .   ? 19.32770  5.29716   35.82169  1.000 28.01914  ? 579 HOH A O      1 
HETATM 5132 O  O      . HOH P 10 .   ? 4.05221   -9.97355  36.99076  1.000 42.40710  ? 580 HOH A O      1 
HETATM 5133 O  O      . HOH P 10 .   ? 3.87298   -6.60263  33.75726  1.000 34.58161  ? 581 HOH A O      1 
HETATM 5134 O  O      . HOH P 10 .   ? 28.06347  17.84735  41.00950  1.000 27.92557  ? 582 HOH A O      1 
HETATM 5135 O  O      . HOH P 10 .   ? 18.780    -20.800   31.565    1.000 26.72446  ? 583 HOH A O      1 
HETATM 5136 O  O      . HOH P 10 .   ? 32.38953  1.80177   46.32820  1.000 51.47761  ? 584 HOH A O      1 
HETATM 5137 O  O      . HOH P 10 .   ? 29.01861  4.82473   30.17726  1.000 34.66666  ? 585 HOH A O      1 
HETATM 5138 O  O      . HOH P 10 .   ? 10.57591  -19.75512 28.45201  1.000 50.52655  ? 586 HOH A O      1 
HETATM 5139 O  O      . HOH P 10 .   ? 26.31216  5.39882   52.97732  1.000 25.45408  ? 587 HOH A O      1 
HETATM 5140 O  O      . HOH P 10 .   ? 14.59129  -4.50267  50.50825  1.000 27.37566  ? 588 HOH A O      1 
HETATM 5141 O  O      . HOH P 10 .   ? 10.68774  6.93861   15.27408  1.000 40.71448  ? 589 HOH A O      1 
HETATM 5142 O  O      . HOH P 10 .   ? 25.47478  16.68175  55.52168  1.000 19.70959  ? 590 HOH A O      1 
HETATM 5143 O  O      . HOH P 10 .   ? 9.77165   -15.73852 28.85550  1.000 32.26447  ? 591 HOH A O      1 
HETATM 5144 O  O      . HOH P 10 .   ? 12.72559  0.46449   51.67884  1.000 25.54625  ? 592 HOH A O      1 
HETATM 5145 O  O      . HOH P 10 .   ? 22.90661  -3.48438  44.87784  1.000 32.80496  ? 593 HOH A O      1 
HETATM 5146 O  O      . HOH P 10 .   ? 0.31479   15.65216  36.75647  1.000 41.27060  ? 594 HOH A O      1 
HETATM 5147 O  O      . HOH P 10 .   ? 18.63867  -11.11256 41.61104  1.000 18.68376  ? 595 HOH A O      1 
HETATM 5148 O  O      . HOH P 10 .   ? 17.38978  15.96429  30.44880  1.000 29.70426  ? 596 HOH A O      1 
HETATM 5149 O  O      . HOH P 10 .   ? 20.09069  -13.14420 38.64819  1.000 36.05933  ? 597 HOH A O      1 
HETATM 5150 O  O      . HOH P 10 .   ? 28.28834  15.24049  40.11027  1.000 26.14252  ? 598 HOH A O      1 
HETATM 5151 O  O      . HOH P 10 .   ? 7.79721   6.87094   18.35899  1.000 38.50369  ? 599 HOH A O      1 
HETATM 5152 O  O      . HOH P 10 .   ? 33.787    6.670     51.048    1.000 40.38024  ? 600 HOH A O      1 
HETATM 5153 O  O      . HOH P 10 .   ? 30.19994  7.99348   32.06365  1.000 37.46807  ? 601 HOH A O      1 
HETATM 5154 O  O      . HOH P 10 .   ? 32.44843  13.26569  52.86803  1.000 29.11008  ? 602 HOH A O      1 
HETATM 5155 O  O      . HOH P 10 .   ? 25.51903  8.28271   37.09095  1.000 27.68769  ? 603 HOH A O      1 
HETATM 5156 O  O      . HOH P 10 .   ? 18.72882  1.84414   53.02943  1.000 27.12705  ? 604 HOH A O      1 
HETATM 5157 O  O      . HOH P 10 .   ? 10.008    -21.432   42.231    1.000 23.63434  ? 605 HOH A O      1 
HETATM 5158 O  O      . HOH P 10 .   ? 21.93089  -6.44485  23.35684  1.000 39.30814  ? 606 HOH A O      1 
HETATM 5159 O  O      . HOH P 10 .   ? 17.71787  3.83060   55.01972  1.000 33.29315  ? 607 HOH A O      1 
HETATM 5160 O  O      . HOH P 10 .   ? 21.17001  25.77796  44.44843  1.000 23.89013  ? 608 HOH A O      1 
HETATM 5161 O  O      . HOH P 10 .   ? 16.42756  -6.73424  30.36757  1.000 39.37732  ? 609 HOH A O      1 
HETATM 5162 O  O      . HOH P 10 .   ? 6.74066   5.01767   55.14752  1.000 37.28021  ? 610 HOH A O      1 
HETATM 5163 O  O      . HOH P 10 .   ? 4.96712   13.90561  50.43362  1.000 32.91019  ? 611 HOH A O      1 
HETATM 5164 O  O      . HOH P 10 .   ? 1.77456   19.60669  32.13641  1.000 47.82565  ? 612 HOH A O      1 
HETATM 5165 O  O      . HOH P 10 .   ? 23.15135  -0.37085  41.04483  1.000 36.73322  ? 613 HOH A O      1 
HETATM 5166 O  O      . HOH P 10 .   ? 12.57323  -0.34421  55.62787  1.000 46.04170  ? 614 HOH A O      1 
HETATM 5167 O  O      . HOH P 10 .   ? 35.72188  6.69801   39.94651  1.000 34.03927  ? 615 HOH A O      1 
HETATM 5168 O  O      . HOH P 10 .   ? 5.18064   11.17276  23.34600  1.000 33.49831  ? 616 HOH A O      1 
HETATM 5169 O  O      . HOH P 10 .   ? 28.41378  18.58237  55.52429  1.000 22.36591  ? 617 HOH A O      1 
HETATM 5170 O  O      . HOH P 10 .   ? 16.44214  -10.63835 24.66929  1.000 34.28189  ? 618 HOH A O      1 
HETATM 5171 O  O      . HOH P 10 .   ? 3.82349   16.30498  51.18577  1.000 44.85748  ? 619 HOH A O      1 
HETATM 5172 O  O      . HOH P 10 .   ? 15.66878  8.80915   44.42874  1.000 20.55907  ? 620 HOH A O      1 
HETATM 5173 O  O      . HOH P 10 .   ? 17.28900  -14.08534 48.77124  1.000 28.40321  ? 621 HOH A O      1 
HETATM 5174 O  O      . HOH P 10 .   ? 23.28133  7.80762   38.38482  1.000 24.16152  ? 622 HOH A O      1 
HETATM 5175 O  O      . HOH P 10 .   ? 7.70145   23.31151  35.88795  1.000 46.99157  ? 623 HOH A O      1 
HETATM 5176 O  O      . HOH P 10 .   ? 11.88752  11.92540  52.98121  1.000 27.02423  ? 624 HOH A O      1 
HETATM 5177 O  O      . HOH P 10 .   ? 11.01673  8.67629   55.02098  1.000 39.11891  ? 625 HOH A O      1 
HETATM 5178 O  O      . HOH P 10 .   ? 2.94061   -17.90914 39.12144  1.000 32.76568  ? 626 HOH A O      1 
HETATM 5179 O  O      . HOH P 10 .   ? 17.92695  -5.52180  48.34403  1.000 26.37797  ? 627 HOH A O      1 
HETATM 5180 O  O      . HOH P 10 .   ? 31.45604  22.15526  41.64392  1.000 23.85646  ? 628 HOH A O      1 
HETATM 5181 O  O      . HOH P 10 .   ? 14.36029  -20.41461 46.31742  1.000 28.18376  ? 629 HOH A O      1 
HETATM 5182 O  O      . HOH P 10 .   ? 3.71987   -3.86433  24.51135  1.000 31.61067  ? 630 HOH A O      1 
HETATM 5183 O  O      . HOH P 10 .   ? 21.30936  -12.93507 29.14256  1.000 26.68601  ? 631 HOH A O      1 
HETATM 5184 O  O      . HOH P 10 .   ? 15.94688  -20.45347 28.34915  1.000 32.70996  ? 632 HOH A O      1 
HETATM 5185 O  O      . HOH P 10 .   ? 33.13358  0.36083   41.91351  1.000 39.18714  ? 633 HOH A O      1 
HETATM 5186 O  O      . HOH P 10 .   ? 20.72472  2.63538   39.02552  1.000 33.95283  ? 634 HOH A O      1 
HETATM 5187 O  O      . HOH P 10 .   ? -2.51909  -2.20076  26.08287  1.000 37.99433  ? 635 HOH A O      1 
HETATM 5188 O  O      . HOH P 10 .   ? 11.082    24.400    52.531    1.000 45.99412  ? 636 HOH A O      1 
HETATM 5189 O  O      . HOH P 10 .   ? 30.21514  15.68146  37.88117  1.000 33.46092  ? 637 HOH A O      1 
HETATM 5190 O  O      . HOH P 10 .   ? 20.79031  -12.70640 36.06515  1.000 24.43197  ? 638 HOH A O      1 
HETATM 5191 O  O      . HOH P 10 .   ? 6.96252   -16.71511 28.80972  1.000 49.48000  ? 639 HOH A O      1 
HETATM 5192 O  O      . HOH P 10 .   ? -1.37575  -10.43792 46.16914  1.000 46.16417  ? 640 HOH A O      1 
HETATM 5193 O  O      . HOH P 10 .   ? 10.99779  -2.05204  49.74610  1.000 22.95018  ? 641 HOH A O      1 
HETATM 5194 O  O      . HOH P 10 .   ? 24.38391  -5.35405  29.55508  1.000 46.07018  ? 642 HOH A O      1 
HETATM 5195 O  O      . HOH P 10 .   ? 24.71441  4.48113   25.07218  1.000 39.88423  ? 643 HOH A O      1 
HETATM 5196 O  O      . HOH P 10 .   ? 0.92108   -11.70961 46.07537  1.000 42.87449  ? 644 HOH A O      1 
HETATM 5197 O  O      . HOH P 10 .   ? -3.20330  -6.85725  40.36133  1.000 50.36435  ? 645 HOH A O      1 
HETATM 5198 O  O      . HOH P 10 .   ? 4.57478   -14.46034 33.53978  1.000 34.81631  ? 646 HOH A O      1 
HETATM 5199 O  O      . HOH P 10 .   ? 25.34621  -0.52240  29.41436  1.000 51.98340  ? 647 HOH A O      1 
HETATM 5200 O  O      . HOH P 10 .   ? -4.98051  -8.25447  35.61048  1.000 46.70021  ? 648 HOH A O      1 
HETATM 5201 O  O      . HOH P 10 .   ? 12.08595  18.33607  52.99475  1.000 38.14471  ? 649 HOH A O      1 
HETATM 5202 O  O      . HOH P 10 .   ? 4.25765   -10.53024 28.85119  1.000 41.57994  ? 650 HOH A O      1 
HETATM 5203 O  O      . HOH P 10 .   ? 21.09316  7.45642   18.82894  1.000 43.83976  ? 651 HOH A O      1 
HETATM 5204 O  O      . HOH P 10 .   ? 8.27084   -14.04488 27.37566  1.000 45.24617  ? 652 HOH A O      1 
HETATM 5205 O  O      . HOH P 10 .   ? -0.95097  12.68882  39.62697  1.000 37.24667  ? 653 HOH A O      1 
HETATM 5206 O  O      . HOH P 10 .   ? 23.174    15.840    62.335    1.000 47.67551  ? 654 HOH A O      1 
HETATM 5207 O  O      . HOH P 10 .   ? 19.26095  28.01743  44.22839  1.000 38.21448  ? 655 HOH A O      1 
HETATM 5208 O  O      . HOH P 10 .   ? 1.57850   -11.17277 34.43295  1.000 51.21245  ? 656 HOH A O      1 
HETATM 5209 O  O      . HOH P 10 .   ? -4.20880  10.10787  39.57926  1.000 34.58539  ? 657 HOH A O      1 
HETATM 5210 O  O      . HOH P 10 .   ? 18.026    26.330    49.148    1.000 55.02558  ? 658 HOH A O      1 
HETATM 5211 O  O      . HOH P 10 .   ? 8.64965   10.43121  16.92052  1.000 48.80930  ? 659 HOH A O      1 
HETATM 5212 O  O      . HOH P 10 .   ? 23.47454  -9.39502  37.32465  1.000 45.32642  ? 660 HOH A O      1 
HETATM 5213 O  O      . HOH P 10 .   ? 5.38745   20.84893  26.19507  1.000 50.76263  ? 661 HOH A O      1 
HETATM 5214 O  O      . HOH P 10 .   ? 13.534    -20.239   26.429    1.000 46.55969  ? 662 HOH A O      1 
HETATM 5215 O  O      . HOH P 10 .   ? 5.59753   24.94514  36.04276  1.000 60.59992  ? 663 HOH A O      1 
HETATM 5216 O  O      . HOH P 10 .   ? 23.05989  5.66951   40.00881  1.000 41.45857  ? 664 HOH A O      1 
HETATM 5217 O  O      . HOH P 10 .   ? -0.73179  -9.54372  42.23577  1.000 40.62385  ? 665 HOH A O      1 
HETATM 5218 O  O      . HOH P 10 .   ? -0.03898  -2.31257  52.10828  1.000 51.24217  ? 666 HOH A O      1 
HETATM 5219 O  O      . HOH P 10 .   ? 22.66341  -7.78014  35.77585  1.000 38.93780  ? 667 HOH A O      1 
HETATM 5220 O  O      . HOH P 10 .   ? 14.57546  17.88530  17.93733  1.000 50.34260  ? 668 HOH A O      1 
HETATM 5221 O  O      . HOH P 10 .   ? 2.23777   -9.44824  30.15065  1.000 39.33404  ? 669 HOH A O      1 
HETATM 5222 O  O      . HOH P 10 .   ? 34.31327  8.74130   38.77381  1.000 50.80089  ? 670 HOH A O      1 
HETATM 5223 O  O      . HOH P 10 .   ? 28.47146  15.82721  32.08012  1.000 34.35614  ? 671 HOH A O      1 
HETATM 5224 O  O      . HOH P 10 .   ? 18.44481  -8.59182  20.92732  1.000 48.98847  ? 672 HOH A O      1 
HETATM 5225 O  O      . HOH P 10 .   ? 2.25482   -12.43604 39.83762  1.000 44.30212  ? 673 HOH A O      1 
HETATM 5226 O  O      . HOH P 10 .   ? 15.02292  2.76775   55.30515  1.000 45.08444  ? 674 HOH A O      1 
HETATM 5227 O  O      . HOH P 10 .   ? 12.332    -21.949   42.566    1.000 30.68709  ? 675 HOH A O      1 
HETATM 5228 O  O      . HOH P 10 .   ? 20.84706  -14.27723 46.70588  1.000 42.50960  ? 676 HOH A O      1 
HETATM 5229 O  O      . HOH P 10 .   ? 21.71338  -0.58137  50.89957  1.000 47.19997  ? 677 HOH A O      1 
HETATM 5230 O  O      . HOH P 10 .   ? 21.46970  2.27378   41.36686  1.000 28.91293  ? 678 HOH A O      1 
HETATM 5231 O  O      . HOH P 10 .   ? 0.76994   -11.15735 49.16540  1.000 49.98466  ? 679 HOH A O      1 
HETATM 5232 O  O      . HOH P 10 .   ? 4.716     -26.097   32.547    1.000 44.44641  ? 680 HOH A O      1 
HETATM 5233 O  O      . HOH P 10 .   ? 18.79255  18.70103  19.89084  1.000 47.48497  ? 681 HOH A O      1 
HETATM 5234 O  O      . HOH P 10 .   ? 1.24176   -11.10341 31.80056  1.000 45.36641  ? 682 HOH A O      1 
HETATM 5235 O  O      . HOH P 10 .   ? 19.74496  -4.00370  49.71637  1.000 40.84663  ? 683 HOH A O      1 
HETATM 5236 O  O      . HOH P 10 .   ? 0.59004   -28.71298 43.22127  1.000 46.83995  ? 684 HOH A O      1 
HETATM 5237 O  O      . HOH P 10 .   ? 16.90762  -4.95940  50.17521  1.000 45.32413  ? 685 HOH A O      1 
HETATM 5238 O  O      . HOH P 10 .   ? 24.17962  -9.06064  30.82307  1.000 46.19252  ? 686 HOH A O      1 
HETATM 5239 O  O      . HOH P 10 .   ? 21.32730  -8.20123  49.51183  1.000 41.50910  ? 687 HOH A O      1 
HETATM 5240 O  O      . HOH P 10 .   ? 20.89587  -14.86230 39.82134  1.000 42.68696  ? 688 HOH A O      1 
HETATM 5241 O  O      . HOH P 10 .   ? 24.61893  -2.17704  42.65894  1.000 36.65778  ? 689 HOH A O      1 
HETATM 5242 O  O      . HOH P 10 .   ? 23.11647  -9.24923  26.56556  1.000 50.25502  ? 690 HOH A O      1 
HETATM 5243 O  O      . HOH P 10 .   ? 21.29596  -11.84557 42.71678  1.000 33.47204  ? 691 HOH A O      1 
HETATM 5244 O  O      . HOH P 10 .   ? 12.80833  -2.20935  51.66889  1.000 29.25620  ? 692 HOH A O      1 
HETATM 5245 O  O      . HOH P 10 .   ? 22.12014  11.02339  16.62795  1.000 46.70581  ? 693 HOH A O      1 
HETATM 5246 O  O      . HOH P 10 .   ? 12.40302  25.85946  45.04496  1.000 39.66999  ? 694 HOH A O      1 
HETATM 5247 O  O      . HOH P 10 .   ? 24.24939  0.40245   51.94429  1.000 45.51538  ? 695 HOH A O      1 
HETATM 5248 O  O      . HOH P 10 .   ? 12.97986  10.32942  54.14087  1.000 38.86398  ? 696 HOH A O      1 
HETATM 5249 O  O      . HOH P 10 .   ? 16.583    14.917    55.908    1.000 40.60702  ? 697 HOH A O      1 
HETATM 5250 O  O      . HOH P 10 .   ? 17.76432  -12.55154 25.57340  1.000 37.25708  ? 698 HOH A O      1 
HETATM 5251 O  O      . HOH P 10 .   ? 30.07718  14.38654  35.70096  1.000 41.18846  ? 699 HOH A O      1 
HETATM 5252 O  O      . HOH P 10 .   ? 12.23329  -2.64145  54.48145  1.000 44.54389  ? 700 HOH A O      1 
HETATM 5253 O  O      . HOH P 10 .   ? 3.72160   -12.66849 35.93355  1.000 41.10142  ? 701 HOH A O      1 
HETATM 5254 O  O      . HOH P 10 .   ? 22.75481  -2.52557  47.24178  1.000 38.30475  ? 702 HOH A O      1 
HETATM 5255 O  O      . HOH P 10 .   ? 22.83699  -7.55860  33.26926  1.000 39.40077  ? 703 HOH A O      1 
HETATM 5256 O  O      . HOH P 10 .   ? 20.80681  -1.90161  48.61205  1.000 34.06446  ? 704 HOH A O      1 
HETATM 5257 O  O      . HOH P 10 .   ? 21.84796  -5.68320  49.76890  1.000 40.81168  ? 705 HOH A O      1 
HETATM 5258 O  O      . HOH P 10 .   ? 13.11527  15.78420  53.08797  1.000 26.89137  ? 706 HOH A O      1 
HETATM 5259 O  O      . HOH P 10 .   ? 17.09746  -9.62049  50.86406  1.000 43.80407  ? 707 HOH A O      1 
HETATM 5260 O  O      . HOH P 10 .   ? -0.11048  -9.39144  28.32741  1.000 46.31962  ? 708 HOH A O      1 
HETATM 5261 O  O      . HOH P 10 .   ? 10.69258  5.92086   56.34718  1.000 44.38703  ? 709 HOH A O      1 
HETATM 5262 O  O      . HOH P 10 .   ? 20.509    -20.678   29.286    1.000 30.09267  ? 710 HOH A O      1 
HETATM 5263 O  O      . HOH P 10 .   ? 23.50439  -10.93776 29.46406  1.000 43.60725  ? 711 HOH A O      1 
HETATM 5264 O  O      . HOH P 10 .   ? 4.18403   23.31835  36.88468  1.000 52.22533  ? 712 HOH A O      1 
HETATM 5265 O  O      . HOH P 10 .   ? 16.41085  -1.25671  54.22567  1.000 39.64221  ? 713 HOH A O      1 
HETATM 5266 O  O      . HOH P 10 .   ? 18.84917  -0.49089  54.46940  1.000 47.81298  ? 714 HOH A O      1 
HETATM 5267 O  O      . HOH P 10 .   ? 22.494    -19.290   28.383    1.000 40.12521  ? 715 HOH A O      1 
HETATM 5268 O  O      . HOH P 10 .   ? 27.61625  -4.90842  43.95053  1.000 63.68781  ? 716 HOH A O      1 
HETATM 5269 O  O      . HOH Q 10 .   ? -6.51356  18.94712  13.88512  1.000 41.93843  ? 501 HOH B O      1 
HETATM 5270 O  O      . HOH Q 10 .   ? 3.67835   26.69858  8.32565   1.000 40.10146  ? 502 HOH B O      1 
HETATM 5271 O  O      . HOH Q 10 .   ? -2.25728  -1.82680  -17.75686 1.000 39.50938  ? 503 HOH B O      1 
HETATM 5272 O  O      . HOH Q 10 .   ? -11.88232 28.57137  5.07834   1.000 39.42282  ? 504 HOH B O      1 
HETATM 5273 O  O      . HOH Q 10 .   ? 3.33252   8.46392   3.06108   1.000 54.36327  ? 505 HOH B O      1 
HETATM 5274 O  O      . HOH Q 10 .   ? -7.66276  4.59726   -3.60892  1.000 43.87366  ? 506 HOH B O      1 
HETATM 5275 O  O      . HOH Q 10 .   ? -9.80751  13.25196  3.61514   1.000 38.75291  ? 507 HOH B O      1 
HETATM 5276 O  O      . HOH Q 10 .   ? -7.00520  22.39076  -3.14006  1.000 34.97132  ? 508 HOH B O      1 
HETATM 5277 O  O      . HOH Q 10 .   ? 0.39375   -8.79181  -17.29931 1.000 49.82024  ? 509 HOH B O      1 
HETATM 5278 O  O      . HOH Q 10 .   ? -9.92212  27.15060  11.42189  1.000 47.86616  ? 510 HOH B O      1 
HETATM 5279 O  O      . HOH Q 10 .   ? 1.75317   -4.59960  -2.98882  1.000 42.28307  ? 511 HOH B O      1 
HETATM 5280 O  O      . HOH Q 10 .   ? -8.84254  19.12171  -12.06316 1.000 37.17336  ? 512 HOH B O      1 
HETATM 5281 O  O      . HOH Q 10 .   ? 8.76969   20.66530  3.77704   1.000 47.55141  ? 513 HOH B O      1 
HETATM 5282 O  O      . HOH Q 10 .   ? -10.37964 9.75498   -2.13595  1.000 41.89127  ? 514 HOH B O      1 
HETATM 5283 O  O      . HOH Q 10 .   ? -8.68010  9.53150   -8.81184  1.000 38.83937  ? 515 HOH B O      1 
HETATM 5284 O  O      . HOH Q 10 .   ? -11.29491 24.75512  -1.36533  1.000 43.92519  ? 516 HOH B O      1 
HETATM 5285 O  O      . HOH Q 10 .   ? -8.69657  18.21143  2.87103   1.000 35.32336  ? 517 HOH B O      1 
HETATM 5286 O  O      . HOH Q 10 .   ? -10.00727 8.56625   -17.27095 1.000 38.69575  ? 518 HOH B O      1 
HETATM 5287 O  O      . HOH Q 10 .   ? -2.62154  11.58511  -4.97223  1.000 35.04456  ? 519 HOH B O      1 
HETATM 5288 O  O      . HOH Q 10 .   ? 4.80545   14.03317  0.31432   1.000 38.80869  ? 520 HOH B O      1 
HETATM 5289 O  O      . HOH Q 10 .   ? 11.03244  0.89560   -3.27482  1.000 45.10861  ? 521 HOH B O      1 
HETATM 5290 O  O      . HOH Q 10 .   ? -12.56138 9.21101   -17.88064 1.000 50.51181  ? 522 HOH B O      1 
HETATM 5291 O  O      . HOH Q 10 .   ? -5.61309  28.43958  -0.50235  1.000 39.59502  ? 523 HOH B O      1 
HETATM 5292 O  O      . HOH Q 10 .   ? -8.26116  10.81325  6.22773   1.000 50.34242  ? 524 HOH B O      1 
HETATM 5293 O  O      . HOH Q 10 .   ? -6.34965  31.04558  -1.33897  1.000 45.44323  ? 525 HOH B O      1 
HETATM 5294 O  O      . HOH Q 10 .   ? 7.54457   17.10928  4.89884   1.000 47.19411  ? 526 HOH B O      1 
HETATM 5295 O  O      . HOH Q 10 .   ? -8.55018  20.75775  13.56766  1.000 46.20808  ? 527 HOH B O      1 
HETATM 5296 O  O      . HOH Q 10 .   ? -0.82237  17.41158  9.54201   1.000 29.26263  ? 528 HOH B O      1 
HETATM 5297 O  O      . HOH Q 10 .   ? 8.26955   16.35673  -2.05212  1.000 40.33550  ? 529 HOH B O      1 
HETATM 5298 O  O      . HOH Q 10 .   ? 14.50805  3.48915   1.94274   1.000 59.66233  ? 530 HOH B O      1 
HETATM 5299 O  O      . HOH Q 10 .   ? -7.23430  13.48232  -24.77835 1.000 37.78977  ? 531 HOH B O      1 
HETATM 5300 O  O      . HOH Q 10 .   ? -9.19853  7.30009   -10.45274 1.000 36.09858  ? 532 HOH B O      1 
HETATM 5301 O  O      . HOH Q 10 .   ? -12.64681 24.47797  4.97764   1.000 51.44772  ? 533 HOH B O      1 
HETATM 5302 O  O      . HOH Q 10 .   ? 1.59488   -2.22458  -1.40761  1.000 36.14659  ? 534 HOH B O      1 
HETATM 5303 O  O      . HOH Q 10 .   ? 10.59361  5.52581   0.37810   1.000 52.87306  ? 535 HOH B O      1 
HETATM 5304 O  O      . HOH Q 10 .   ? -6.69809  6.24378   -24.05911 1.000 42.52314  ? 536 HOH B O      1 
HETATM 5305 O  O      . HOH Q 10 .   ? 5.24129   24.12688  8.25049   1.000 42.52287  ? 537 HOH B O      1 
HETATM 5306 O  O      . HOH Q 10 .   ? -2.02851  18.86157  -21.38473 1.000 46.89916  ? 538 HOH B O      1 
HETATM 5307 O  O      . HOH Q 10 .   ? -8.80467  22.68298  -5.04454  1.000 38.88644  ? 539 HOH B O      1 
HETATM 5308 O  O      . HOH Q 10 .   ? -6.86450  14.11789  -18.84546 1.000 34.80746  ? 540 HOH B O      1 
HETATM 5309 O  O      . HOH Q 10 .   ? -5.59519  -5.09698  -1.61297  1.000 44.61371  ? 541 HOH B O      1 
HETATM 5310 O  O      . HOH Q 10 .   ? -7.79855  -9.78055  -2.92613  1.000 55.31755  ? 542 HOH B O      1 
HETATM 5311 O  O      . HOH Q 10 .   ? -7.59306  14.31409  8.67452   1.000 37.17901  ? 543 HOH B O      1 
HETATM 5312 O  O      . HOH Q 10 .   ? -0.933    34.556    2.169     1.000 40.70594  ? 544 HOH B O      1 
HETATM 5313 O  O      . HOH Q 10 .   ? -0.92836  -12.47928 -10.25490 1.000 38.22987  ? 545 HOH B O      1 
HETATM 5314 O  O      . HOH Q 10 .   ? 7.12731   -4.41800  -0.52507  1.000 43.88270  ? 546 HOH B O      1 
HETATM 5315 O  O      . HOH Q 10 .   ? -9.65087  10.74290  1.29426   1.000 39.04963  ? 547 HOH B O      1 
HETATM 5316 O  O      . HOH Q 10 .   ? -11.58167 12.53458  0.72637   1.000 43.15938  ? 548 HOH B O      1 
HETATM 5317 O  O      . HOH Q 10 .   ? -4.27526  15.37324  7.82808   1.000 38.72528  ? 549 HOH B O      1 
HETATM 5318 O  O      . HOH Q 10 .   ? -1.63236  17.63315  -3.33463  1.000 37.77994  ? 550 HOH B O      1 
HETATM 5319 O  O      . HOH Q 10 .   ? -0.85005  8.01279   -4.94600  1.000 38.76405  ? 551 HOH B O      1 
HETATM 5320 O  O      . HOH Q 10 .   ? -7.85202  6.92624   -7.13374  1.000 33.84159  ? 552 HOH B O      1 
HETATM 5321 O  O      . HOH Q 10 .   ? -0.74131  5.47510   3.42472   1.000 43.93705  ? 553 HOH B O      1 
HETATM 5322 O  O      . HOH Q 10 .   ? -4.04634  -11.37789 -5.15442  1.000 36.96302  ? 554 HOH B O      1 
HETATM 5323 O  O      . HOH Q 10 .   ? -3.71635  9.47861   1.66409   1.000 35.96407  ? 555 HOH B O      1 
HETATM 5324 O  O      . HOH Q 10 .   ? -9.44954  9.48207   -4.81602  1.000 37.67589  ? 556 HOH B O      1 
HETATM 5325 O  O      . HOH Q 10 .   ? 4.61191   11.44458  0.31469   1.000 42.82739  ? 557 HOH B O      1 
HETATM 5326 O  O      . HOH Q 10 .   ? -5.17033  3.37705   -0.64757  1.000 36.66938  ? 558 HOH B O      1 
HETATM 5327 O  O      . HOH Q 10 .   ? 14.36887  -4.75719  -1.34902  1.000 51.75563  ? 559 HOH B O      1 
HETATM 5328 O  O      . HOH Q 10 .   ? 4.290     31.259    11.562    1.000 41.43283  ? 560 HOH B O      1 
HETATM 5329 O  O      . HOH Q 10 .   ? -6.60640  21.18890  -25.60113 1.000 48.39968  ? 561 HOH B O      1 
HETATM 5330 O  O      . HOH Q 10 .   ? 5.72235   16.55190  2.88542   1.000 39.97879  ? 562 HOH B O      1 
HETATM 5331 O  O      . HOH Q 10 .   ? -13.95731 15.14242  -23.09887 1.000 48.66262  ? 563 HOH B O      1 
HETATM 5332 O  O      . HOH Q 10 .   ? -10.42128 26.03107  8.77522   1.000 40.25676  ? 564 HOH B O      1 
HETATM 5333 O  O      . HOH Q 10 .   ? -7.684    -14.984   1.109     1.000 56.67453  ? 565 HOH B O      1 
HETATM 5334 O  O      . HOH Q 10 .   ? 7.24517   14.12588  -1.24951  1.000 45.90206  ? 566 HOH B O      1 
HETATM 5335 O  O      . HOH Q 10 .   ? -10.86919 24.61257  -4.12611  1.000 48.74149  ? 567 HOH B O      1 
HETATM 5336 O  O      . HOH Q 10 .   ? 4.27553   14.57814  3.14871   1.000 42.44106  ? 568 HOH B O      1 
HETATM 5337 O  O      . HOH Q 10 .   ? 2.61078   11.10870  1.53602   1.000 42.00847  ? 569 HOH B O      1 
HETATM 5338 O  O      . HOH Q 10 .   ? 9.20963   13.50644  16.94478  1.000 54.38441  ? 570 HOH B O      1 
HETATM 5339 O  O      . HOH Q 10 .   ? -2.78047  18.22043  -23.54008 1.000 49.62777  ? 571 HOH B O      1 
HETATM 5340 O  O      . HOH Q 10 .   ? 1.81454   6.67348   4.87661   1.000 48.83066  ? 572 HOH B O      1 
HETATM 5341 O  O      . HOH Q 10 .   ? -11.57152 11.57411  4.71097   1.000 55.11464  ? 573 HOH B O      1 
HETATM 5342 O  O      . HOH Q 10 .   ? 1.31266   -3.21022  1.21806   1.000 45.64611  ? 574 HOH B O      1 
HETATM 5343 O  O      . HOH Q 10 .   ? -9.49654  6.59477   -5.09772  1.000 43.52769  ? 575 HOH B O      1 
HETATM 5344 O  O      . HOH Q 10 .   ? -4.69507  6.93687   2.35235   1.000 44.36938  ? 576 HOH B O      1 
HETATM 5345 O  O      . HOH Q 10 .   ? 6.85576   1.58119   4.86634   1.000 49.33342  ? 577 HOH B O      1 
HETATM 5346 O  O      . HOH Q 10 .   ? 21.322    21.606    -29.200   1.000 43.40810  ? 578 HOH B O      1 
HETATM 5347 O  O      . HOH Q 10 .   ? -20.63660 20.26180  -26.02122 1.000 39.74002  ? 579 HOH B O      1 
HETATM 5348 O  O      . HOH Q 10 .   ? -24.29326 21.78772  -27.92010 1.000 38.09469  ? 580 HOH B O      1 
# 
