data_8ZW6
# 
_entry.id   8ZW6 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZW6         pdb_00008zw6 10.2210/pdb8zw6/pdb 
WWPDB D_1300041590 ?            ?                   
EMDB  EMD-60517    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZW6 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus S228 mutant complexed with avian receptor analog LSTa' 
_pdbx_database_related.db_id          EMD-60517 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              gaof@im.ac.cn 
_pdbx_contact_author.name_first         'George Fu' 
_pdbx_contact_author.name_last          Gao 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3869-615X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hao, T.J.' 1 ? 
'Xie, Y.F.' 2 ? 
'Chai, Y.'  3 ? 
'Song, H.'  4 ? 
'Gao, G.F.' 5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus S228 mutant complexed with avian receptor analog LSTa' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hao, T.J.' 1 ? 
primary 'Xie, Y.F.' 2 ? 
primary 'Chai, Y.'  3 ? 
primary 'Song, H.'  4 ? 
primary 'Gao, G.F.' 5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Hemagglutinin 56323.758 3 ? ? ? 'HN/4-10 H3N8 S228 HA complexed with LSTa' 
2 branched    man 
;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
910.823   3 ? ? ? ?                                          
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3 ? ? ? ? 
4 branched    man 'N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose' 471.411   3 ? ? ? ? 
5 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   3 ? ? ? ?                                          
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;LQQNLPGKDSSTATLCLGHHSVPNGTIVKTITDDQIEVTNATELVQNSSTGKICNNPHKVLDGRDCTLIDAMLGDPHCDV
FQDEKWDLFVERSSAFSNCYPYDVPDYASLRSLIASSGTLDFITESFTWAGVSQNGGSSACKRGPANGFFSRLNWLTKSG
SSYPLLNVTMPNNYNFDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIVPNIGSRPWVRGQSSRISIYWTIVK
PGDVLVINSNGNLIAPRGFFKIRTGRSSIMRSDAPIETCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLAT
GMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKE
FSEVEGRIQDLEKYVEDTKVDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACI
ESIRNGTYDHDIYRDEALNNRF
;
_entity_poly.pdbx_seq_one_letter_code_can   
;LQQNLPGKDSSTATLCLGHHSVPNGTIVKTITDDQIEVTNATELVQNSSTGKICNNPHKVLDGRDCTLIDAMLGDPHCDV
FQDEKWDLFVERSSAFSNCYPYDVPDYASLRSLIASSGTLDFITESFTWAGVSQNGGSSACKRGPANGFFSRLNWLTKSG
SSYPLLNVTMPNNYNFDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIVPNIGSRPWVRGQSSRISIYWTIVK
PGDVLVINSNGNLIAPRGFFKIRTGRSSIMRSDAPIETCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLAT
GMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKE
FSEVEGRIQDLEKYVEDTKVDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACI
ESIRNGTYDHDIYRDEALNNRF
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LEU n 
1 2   GLN n 
1 3   GLN n 
1 4   ASN n 
1 5   LEU n 
1 6   PRO n 
1 7   GLY n 
1 8   LYS n 
1 9   ASP n 
1 10  SER n 
1 11  SER n 
1 12  THR n 
1 13  ALA n 
1 14  THR n 
1 15  LEU n 
1 16  CYS n 
1 17  LEU n 
1 18  GLY n 
1 19  HIS n 
1 20  HIS n 
1 21  SER n 
1 22  VAL n 
1 23  PRO n 
1 24  ASN n 
1 25  GLY n 
1 26  THR n 
1 27  ILE n 
1 28  VAL n 
1 29  LYS n 
1 30  THR n 
1 31  ILE n 
1 32  THR n 
1 33  ASP n 
1 34  ASP n 
1 35  GLN n 
1 36  ILE n 
1 37  GLU n 
1 38  VAL n 
1 39  THR n 
1 40  ASN n 
1 41  ALA n 
1 42  THR n 
1 43  GLU n 
1 44  LEU n 
1 45  VAL n 
1 46  GLN n 
1 47  ASN n 
1 48  SER n 
1 49  SER n 
1 50  THR n 
1 51  GLY n 
1 52  LYS n 
1 53  ILE n 
1 54  CYS n 
1 55  ASN n 
1 56  ASN n 
1 57  PRO n 
1 58  HIS n 
1 59  LYS n 
1 60  VAL n 
1 61  LEU n 
1 62  ASP n 
1 63  GLY n 
1 64  ARG n 
1 65  ASP n 
1 66  CYS n 
1 67  THR n 
1 68  LEU n 
1 69  ILE n 
1 70  ASP n 
1 71  ALA n 
1 72  MET n 
1 73  LEU n 
1 74  GLY n 
1 75  ASP n 
1 76  PRO n 
1 77  HIS n 
1 78  CYS n 
1 79  ASP n 
1 80  VAL n 
1 81  PHE n 
1 82  GLN n 
1 83  ASP n 
1 84  GLU n 
1 85  LYS n 
1 86  TRP n 
1 87  ASP n 
1 88  LEU n 
1 89  PHE n 
1 90  VAL n 
1 91  GLU n 
1 92  ARG n 
1 93  SER n 
1 94  SER n 
1 95  ALA n 
1 96  PHE n 
1 97  SER n 
1 98  ASN n 
1 99  CYS n 
1 100 TYR n 
1 101 PRO n 
1 102 TYR n 
1 103 ASP n 
1 104 VAL n 
1 105 PRO n 
1 106 ASP n 
1 107 TYR n 
1 108 ALA n 
1 109 SER n 
1 110 LEU n 
1 111 ARG n 
1 112 SER n 
1 113 LEU n 
1 114 ILE n 
1 115 ALA n 
1 116 SER n 
1 117 SER n 
1 118 GLY n 
1 119 THR n 
1 120 LEU n 
1 121 ASP n 
1 122 PHE n 
1 123 ILE n 
1 124 THR n 
1 125 GLU n 
1 126 SER n 
1 127 PHE n 
1 128 THR n 
1 129 TRP n 
1 130 ALA n 
1 131 GLY n 
1 132 VAL n 
1 133 SER n 
1 134 GLN n 
1 135 ASN n 
1 136 GLY n 
1 137 GLY n 
1 138 SER n 
1 139 SER n 
1 140 ALA n 
1 141 CYS n 
1 142 LYS n 
1 143 ARG n 
1 144 GLY n 
1 145 PRO n 
1 146 ALA n 
1 147 ASN n 
1 148 GLY n 
1 149 PHE n 
1 150 PHE n 
1 151 SER n 
1 152 ARG n 
1 153 LEU n 
1 154 ASN n 
1 155 TRP n 
1 156 LEU n 
1 157 THR n 
1 158 LYS n 
1 159 SER n 
1 160 GLY n 
1 161 SER n 
1 162 SER n 
1 163 TYR n 
1 164 PRO n 
1 165 LEU n 
1 166 LEU n 
1 167 ASN n 
1 168 VAL n 
1 169 THR n 
1 170 MET n 
1 171 PRO n 
1 172 ASN n 
1 173 ASN n 
1 174 TYR n 
1 175 ASN n 
1 176 PHE n 
1 177 ASP n 
1 178 LYS n 
1 179 LEU n 
1 180 TYR n 
1 181 ILE n 
1 182 TRP n 
1 183 GLY n 
1 184 VAL n 
1 185 HIS n 
1 186 HIS n 
1 187 PRO n 
1 188 SER n 
1 189 THR n 
1 190 ASN n 
1 191 GLN n 
1 192 GLU n 
1 193 GLN n 
1 194 THR n 
1 195 ASN n 
1 196 LEU n 
1 197 TYR n 
1 198 VAL n 
1 199 GLN n 
1 200 ALA n 
1 201 SER n 
1 202 GLY n 
1 203 ARG n 
1 204 VAL n 
1 205 THR n 
1 206 VAL n 
1 207 SER n 
1 208 THR n 
1 209 ARG n 
1 210 ARG n 
1 211 SER n 
1 212 GLN n 
1 213 GLN n 
1 214 THR n 
1 215 ILE n 
1 216 VAL n 
1 217 PRO n 
1 218 ASN n 
1 219 ILE n 
1 220 GLY n 
1 221 SER n 
1 222 ARG n 
1 223 PRO n 
1 224 TRP n 
1 225 VAL n 
1 226 ARG n 
1 227 GLY n 
1 228 GLN n 
1 229 SER n 
1 230 SER n 
1 231 ARG n 
1 232 ILE n 
1 233 SER n 
1 234 ILE n 
1 235 TYR n 
1 236 TRP n 
1 237 THR n 
1 238 ILE n 
1 239 VAL n 
1 240 LYS n 
1 241 PRO n 
1 242 GLY n 
1 243 ASP n 
1 244 VAL n 
1 245 LEU n 
1 246 VAL n 
1 247 ILE n 
1 248 ASN n 
1 249 SER n 
1 250 ASN n 
1 251 GLY n 
1 252 ASN n 
1 253 LEU n 
1 254 ILE n 
1 255 ALA n 
1 256 PRO n 
1 257 ARG n 
1 258 GLY n 
1 259 PHE n 
1 260 PHE n 
1 261 LYS n 
1 262 ILE n 
1 263 ARG n 
1 264 THR n 
1 265 GLY n 
1 266 ARG n 
1 267 SER n 
1 268 SER n 
1 269 ILE n 
1 270 MET n 
1 271 ARG n 
1 272 SER n 
1 273 ASP n 
1 274 ALA n 
1 275 PRO n 
1 276 ILE n 
1 277 GLU n 
1 278 THR n 
1 279 CYS n 
1 280 ILE n 
1 281 SER n 
1 282 GLU n 
1 283 CYS n 
1 284 ILE n 
1 285 THR n 
1 286 PRO n 
1 287 ASN n 
1 288 GLY n 
1 289 SER n 
1 290 ILE n 
1 291 PRO n 
1 292 ASN n 
1 293 ASP n 
1 294 LYS n 
1 295 PRO n 
1 296 PHE n 
1 297 GLN n 
1 298 ASN n 
1 299 VAL n 
1 300 ASN n 
1 301 LYS n 
1 302 ILE n 
1 303 THR n 
1 304 TYR n 
1 305 GLY n 
1 306 ALA n 
1 307 CYS n 
1 308 PRO n 
1 309 LYS n 
1 310 TYR n 
1 311 VAL n 
1 312 LYS n 
1 313 GLN n 
1 314 ASN n 
1 315 THR n 
1 316 LEU n 
1 317 LYS n 
1 318 LEU n 
1 319 ALA n 
1 320 THR n 
1 321 GLY n 
1 322 MET n 
1 323 ARG n 
1 324 ASN n 
1 325 VAL n 
1 326 PRO n 
1 327 GLU n 
1 328 LYS n 
1 329 GLN n 
1 330 THR n 
1 331 ARG n 
1 332 GLY n 
1 333 LEU n 
1 334 PHE n 
1 335 GLY n 
1 336 ALA n 
1 337 ILE n 
1 338 ALA n 
1 339 GLY n 
1 340 PHE n 
1 341 ILE n 
1 342 GLU n 
1 343 ASN n 
1 344 GLY n 
1 345 TRP n 
1 346 GLU n 
1 347 GLY n 
1 348 MET n 
1 349 ILE n 
1 350 ASP n 
1 351 GLY n 
1 352 TRP n 
1 353 TYR n 
1 354 GLY n 
1 355 PHE n 
1 356 ARG n 
1 357 HIS n 
1 358 GLN n 
1 359 ASN n 
1 360 SER n 
1 361 GLU n 
1 362 GLY n 
1 363 THR n 
1 364 GLY n 
1 365 GLN n 
1 366 ALA n 
1 367 ALA n 
1 368 ASP n 
1 369 LEU n 
1 370 LYS n 
1 371 SER n 
1 372 THR n 
1 373 GLN n 
1 374 ALA n 
1 375 ALA n 
1 376 ILE n 
1 377 ASP n 
1 378 GLN n 
1 379 ILE n 
1 380 ASN n 
1 381 GLY n 
1 382 LYS n 
1 383 LEU n 
1 384 ASN n 
1 385 ARG n 
1 386 VAL n 
1 387 ILE n 
1 388 GLU n 
1 389 LYS n 
1 390 THR n 
1 391 ASN n 
1 392 GLU n 
1 393 LYS n 
1 394 PHE n 
1 395 HIS n 
1 396 GLN n 
1 397 ILE n 
1 398 GLU n 
1 399 LYS n 
1 400 GLU n 
1 401 PHE n 
1 402 SER n 
1 403 GLU n 
1 404 VAL n 
1 405 GLU n 
1 406 GLY n 
1 407 ARG n 
1 408 ILE n 
1 409 GLN n 
1 410 ASP n 
1 411 LEU n 
1 412 GLU n 
1 413 LYS n 
1 414 TYR n 
1 415 VAL n 
1 416 GLU n 
1 417 ASP n 
1 418 THR n 
1 419 LYS n 
1 420 VAL n 
1 421 ASP n 
1 422 LEU n 
1 423 TRP n 
1 424 SER n 
1 425 TYR n 
1 426 ASN n 
1 427 ALA n 
1 428 GLU n 
1 429 LEU n 
1 430 LEU n 
1 431 VAL n 
1 432 ALA n 
1 433 LEU n 
1 434 GLU n 
1 435 ASN n 
1 436 GLN n 
1 437 HIS n 
1 438 THR n 
1 439 ILE n 
1 440 ASP n 
1 441 LEU n 
1 442 THR n 
1 443 ASP n 
1 444 SER n 
1 445 GLU n 
1 446 MET n 
1 447 ASN n 
1 448 LYS n 
1 449 LEU n 
1 450 PHE n 
1 451 GLU n 
1 452 LYS n 
1 453 THR n 
1 454 ARG n 
1 455 ARG n 
1 456 GLN n 
1 457 LEU n 
1 458 ARG n 
1 459 GLU n 
1 460 ASN n 
1 461 ALA n 
1 462 GLU n 
1 463 ASP n 
1 464 MET n 
1 465 GLY n 
1 466 ASN n 
1 467 GLY n 
1 468 CYS n 
1 469 PHE n 
1 470 LYS n 
1 471 ILE n 
1 472 TYR n 
1 473 HIS n 
1 474 LYS n 
1 475 CYS n 
1 476 ASP n 
1 477 ASN n 
1 478 ALA n 
1 479 CYS n 
1 480 ILE n 
1 481 GLU n 
1 482 SER n 
1 483 ILE n 
1 484 ARG n 
1 485 ASN n 
1 486 GLY n 
1 487 THR n 
1 488 TYR n 
1 489 ASP n 
1 490 HIS n 
1 491 ASP n 
1 492 ILE n 
1 493 TYR n 
1 494 ARG n 
1 495 ASP n 
1 496 GLU n 
1 497 ALA n 
1 498 LEU n 
1 499 ASN n 
1 500 ASN n 
1 501 ARG n 
1 502 PHE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   502 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Influenza A virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     11320 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
4 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 'DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH'                                                   
'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1' WURCS PDB2Glycan 
1.1.0 
3 2 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}'    LINUCS PDB-CARE   
?     
4 3 DGlcpNAcb1-4DGlcpNAcb1-ROH                                                                                  
'Glycam Condensed Sequence' GMML       1.0   
5 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                                                       WURCS PDB2Glycan 
1.1.0 
6 3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'                                                             LINUCS PDB-CARE   
?     
7 4 DNeup5Aca2-3DGalpb1-ROH                                                                                     
'Glycam Condensed Sequence' GMML       1.0   
8 4 'WURCS=2.0/2,2,1/[a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2/a3-b2'                                     WURCS PDB2Glycan 
1.1.0 
9 4 '[][b-D-Galp]{[(3+2)][a-D-Neup5Ac]{}}'                                                                      LINUCS PDB-CARE   
?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 2 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 2 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
4 2 5 MAN C1 O1 3 BMA O6 HO6 sing ? 
5 3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
6 4 2 SIA C2 O2 1 GAL O3 HO3 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GAL 'D-saccharide, beta linking'  . beta-D-galactopyranose                   'beta-D-galactose; D-galactose; galactose' 
'C6 H12 O6'      180.156 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose                    'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6' 
180.156 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
SIA 'D-saccharide, alpha linking' . 'N-acetyl-alpha-neuraminic acid'         
'N-acetylneuraminic acid; sialic acid; alpha-sialic acid; O-SIALIC ACID' 'C11 H19 N O9'   309.270 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
GAL 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpb                         
GAL 'COMMON NAME'                         GMML     1.0 b-D-galactopyranose            
GAL 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Galp                       
GAL 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Gal                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
SIA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DNeup5Aca                      
SIA 'COMMON NAME'                         GMML     1.0 'N-acetyl-a-D-neuraminic acid' 
SIA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Neup5Ac                    
SIA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Neu5Ac                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LEU 1   1   ?   ?   ?   A . n 
A 1 2   GLN 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   ASN 4   4   ?   ?   ?   A . n 
A 1 5   LEU 5   5   ?   ?   ?   A . n 
A 1 6   PRO 6   6   ?   ?   ?   A . n 
A 1 7   GLY 7   7   ?   ?   ?   A . n 
A 1 8   LYS 8   8   ?   ?   ?   A . n 
A 1 9   ASP 9   9   ?   ?   ?   A . n 
A 1 10  SER 10  10  ?   ?   ?   A . n 
A 1 11  SER 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  12  THR THR A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  THR 14  14  14  THR THR A . n 
A 1 15  LEU 15  15  15  LEU LEU A . n 
A 1 16  CYS 16  16  16  CYS CYS A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  GLY 18  18  18  GLY GLY A . n 
A 1 19  HIS 19  19  19  HIS HIS A . n 
A 1 20  HIS 20  20  20  HIS HIS A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  PRO 23  23  23  PRO PRO A . n 
A 1 24  ASN 24  24  24  ASN ASN A . n 
A 1 25  GLY 25  25  25  GLY GLY A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  ILE 27  27  27  ILE ILE A . n 
A 1 28  VAL 28  28  28  VAL VAL A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  ILE 31  31  31  ILE ILE A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  GLU 37  37  37  GLU GLU A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  THR 39  39  39  THR THR A . n 
A 1 40  ASN 40  40  40  ASN ASN A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  THR 42  42  42  THR THR A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  VAL 45  45  45  VAL VAL A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  SER 48  48  48  SER SER A . n 
A 1 49  SER 49  49  49  SER SER A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  LYS 52  52  52  LYS LYS A . n 
A 1 53  ILE 53  53  53  ILE ILE A . n 
A 1 54  CYS 54  54  54  CYS CYS A . n 
A 1 55  ASN 55  55  55  ASN ASN A . n 
A 1 56  ASN 56  56  56  ASN ASN A . n 
A 1 57  PRO 57  57  57  PRO PRO A . n 
A 1 58  HIS 58  58  58  HIS HIS A . n 
A 1 59  LYS 59  59  59  LYS LYS A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  ASP 62  62  62  ASP ASP A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  ARG 64  64  64  ARG ARG A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  CYS 66  66  66  CYS CYS A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  ASP 70  70  70  ASP ASP A . n 
A 1 71  ALA 71  71  71  ALA ALA A . n 
A 1 72  MET 72  72  72  MET MET A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  ASP 75  75  75  ASP ASP A . n 
A 1 76  PRO 76  76  76  PRO PRO A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  CYS 78  78  78  CYS CYS A . n 
A 1 79  ASP 79  79  79  ASP ASP A . n 
A 1 80  VAL 80  80  80  VAL VAL A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  GLN 82  82  82  GLN GLN A . n 
A 1 83  ASP 83  83  83  ASP ASP A . n 
A 1 84  GLU 84  84  84  GLU GLU A . n 
A 1 85  LYS 85  85  85  LYS LYS A . n 
A 1 86  TRP 86  86  86  TRP TRP A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  PHE 89  89  89  PHE PHE A . n 
A 1 90  VAL 90  90  90  VAL VAL A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  ARG 92  92  92  ARG ARG A . n 
A 1 93  SER 93  93  93  SER SER A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  PHE 96  96  96  PHE PHE A . n 
A 1 97  SER 97  97  97  SER SER A . n 
A 1 98  ASN 98  98  98  ASN ASN A . n 
A 1 99  CYS 99  99  99  CYS CYS A . n 
A 1 100 TYR 100 100 ?   ?   ?   A . n 
A 1 101 PRO 101 101 101 PRO PRO A . n 
A 1 102 TYR 102 102 102 TYR TYR A . n 
A 1 103 ASP 103 103 103 ASP ASP A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 PRO 105 105 105 PRO PRO A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 TYR 107 107 107 TYR TYR A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 ILE 114 114 114 ILE ILE A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 SER 116 116 116 SER SER A . n 
A 1 117 SER 117 117 117 SER SER A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 THR 119 119 119 THR THR A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 ASP 121 121 121 ASP ASP A . n 
A 1 122 PHE 122 122 122 PHE PHE A . n 
A 1 123 ILE 123 123 123 ILE ILE A . n 
A 1 124 THR 124 124 124 THR THR A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 SER 126 126 126 SER SER A . n 
A 1 127 PHE 127 127 127 PHE PHE A . n 
A 1 128 THR 128 128 128 THR THR A . n 
A 1 129 TRP 129 129 129 TRP TRP A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 SER 133 133 133 SER SER A . n 
A 1 134 GLN 134 134 134 GLN GLN A . n 
A 1 135 ASN 135 135 135 ASN ASN A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 CYS 141 141 141 CYS CYS A . n 
A 1 142 LYS 142 142 142 LYS LYS A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 GLY 144 144 144 GLY GLY A . n 
A 1 145 PRO 145 145 145 PRO PRO A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ASN 147 147 147 ASN ASN A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 PHE 149 149 149 PHE PHE A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 SER 151 151 151 SER SER A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 ASN 154 154 154 ASN ASN A . n 
A 1 155 TRP 155 155 155 TRP TRP A . n 
A 1 156 LEU 156 156 156 LEU LEU A . n 
A 1 157 THR 157 157 157 THR THR A . n 
A 1 158 LYS 158 158 158 LYS LYS A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 GLY 160 160 160 GLY GLY A . n 
A 1 161 SER 161 161 161 SER SER A . n 
A 1 162 SER 162 162 162 SER SER A . n 
A 1 163 TYR 163 163 163 TYR TYR A . n 
A 1 164 PRO 164 164 164 PRO PRO A . n 
A 1 165 LEU 165 165 165 LEU LEU A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 ASN 167 167 167 ASN ASN A . n 
A 1 168 VAL 168 168 168 VAL VAL A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 MET 170 170 170 MET MET A . n 
A 1 171 PRO 171 171 171 PRO PRO A . n 
A 1 172 ASN 172 172 172 ASN ASN A . n 
A 1 173 ASN 173 173 173 ASN ASN A . n 
A 1 174 TYR 174 174 174 TYR TYR A . n 
A 1 175 ASN 175 175 175 ASN ASN A . n 
A 1 176 PHE 176 176 176 PHE PHE A . n 
A 1 177 ASP 177 177 177 ASP ASP A . n 
A 1 178 LYS 178 178 178 LYS LYS A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 TYR 180 180 180 TYR TYR A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 TRP 182 182 182 TRP TRP A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 HIS 185 185 185 HIS HIS A . n 
A 1 186 HIS 186 186 186 HIS HIS A . n 
A 1 187 PRO 187 187 187 PRO PRO A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 THR 189 189 189 THR THR A . n 
A 1 190 ASN 190 190 190 ASN ASN A . n 
A 1 191 GLN 191 191 191 GLN GLN A . n 
A 1 192 GLU 192 192 192 GLU GLU A . n 
A 1 193 GLN 193 193 193 GLN GLN A . n 
A 1 194 THR 194 194 194 THR THR A . n 
A 1 195 ASN 195 195 195 ASN ASN A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 TYR 197 197 197 TYR TYR A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 GLN 199 199 199 GLN GLN A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 ARG 209 209 209 ARG ARG A . n 
A 1 210 ARG 210 210 210 ARG ARG A . n 
A 1 211 SER 211 211 211 SER SER A . n 
A 1 212 GLN 212 212 212 GLN GLN A . n 
A 1 213 GLN 213 213 213 GLN GLN A . n 
A 1 214 THR 214 214 214 THR THR A . n 
A 1 215 ILE 215 215 215 ILE ILE A . n 
A 1 216 VAL 216 216 216 VAL VAL A . n 
A 1 217 PRO 217 217 217 PRO PRO A . n 
A 1 218 ASN 218 218 218 ASN ASN A . n 
A 1 219 ILE 219 219 219 ILE ILE A . n 
A 1 220 GLY 220 220 220 GLY GLY A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 ARG 222 222 222 ARG ARG A . n 
A 1 223 PRO 223 223 223 PRO PRO A . n 
A 1 224 TRP 224 224 224 TRP TRP A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 GLN 228 228 228 GLN GLN A . n 
A 1 229 SER 229 229 229 SER SER A . n 
A 1 230 SER 230 230 230 SER SER A . n 
A 1 231 ARG 231 231 231 ARG ARG A . n 
A 1 232 ILE 232 232 232 ILE ILE A . n 
A 1 233 SER 233 233 233 SER SER A . n 
A 1 234 ILE 234 234 234 ILE ILE A . n 
A 1 235 TYR 235 235 235 TYR TYR A . n 
A 1 236 TRP 236 236 236 TRP TRP A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 LYS 240 240 240 LYS LYS A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 GLY 242 242 242 GLY GLY A . n 
A 1 243 ASP 243 243 243 ASP ASP A . n 
A 1 244 VAL 244 244 244 VAL VAL A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 ILE 247 247 247 ILE ILE A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 SER 249 249 249 SER SER A . n 
A 1 250 ASN 250 250 250 ASN ASN A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 ASN 252 252 252 ASN ASN A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ILE 254 254 254 ILE ILE A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 PRO 256 256 256 PRO PRO A . n 
A 1 257 ARG 257 257 257 ARG ARG A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 PHE 259 259 259 PHE PHE A . n 
A 1 260 PHE 260 260 260 PHE PHE A . n 
A 1 261 LYS 261 261 261 LYS LYS A . n 
A 1 262 ILE 262 262 262 ILE ILE A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 THR 264 264 264 THR THR A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 ARG 266 266 266 ARG ARG A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 SER 268 268 268 SER SER A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 MET 270 270 270 MET MET A . n 
A 1 271 ARG 271 271 271 ARG ARG A . n 
A 1 272 SER 272 272 272 SER SER A . n 
A 1 273 ASP 273 273 273 ASP ASP A . n 
A 1 274 ALA 274 274 274 ALA ALA A . n 
A 1 275 PRO 275 275 275 PRO PRO A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 GLU 277 277 277 GLU GLU A . n 
A 1 278 THR 278 278 278 THR THR A . n 
A 1 279 CYS 279 279 279 CYS CYS A . n 
A 1 280 ILE 280 280 280 ILE ILE A . n 
A 1 281 SER 281 281 281 SER SER A . n 
A 1 282 GLU 282 282 282 GLU GLU A . n 
A 1 283 CYS 283 283 283 CYS CYS A . n 
A 1 284 ILE 284 284 284 ILE ILE A . n 
A 1 285 THR 285 285 285 THR THR A . n 
A 1 286 PRO 286 286 286 PRO PRO A . n 
A 1 287 ASN 287 287 287 ASN ASN A . n 
A 1 288 GLY 288 288 288 GLY GLY A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 PRO 291 291 291 PRO PRO A . n 
A 1 292 ASN 292 292 292 ASN ASN A . n 
A 1 293 ASP 293 293 293 ASP ASP A . n 
A 1 294 LYS 294 294 294 LYS LYS A . n 
A 1 295 PRO 295 295 295 PRO PRO A . n 
A 1 296 PHE 296 296 296 PHE PHE A . n 
A 1 297 GLN 297 297 297 GLN GLN A . n 
A 1 298 ASN 298 298 298 ASN ASN A . n 
A 1 299 VAL 299 299 299 VAL VAL A . n 
A 1 300 ASN 300 300 300 ASN ASN A . n 
A 1 301 LYS 301 301 301 LYS LYS A . n 
A 1 302 ILE 302 302 302 ILE ILE A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 TYR 304 304 304 TYR TYR A . n 
A 1 305 GLY 305 305 305 GLY GLY A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 CYS 307 307 307 CYS CYS A . n 
A 1 308 PRO 308 308 308 PRO PRO A . n 
A 1 309 LYS 309 309 309 LYS LYS A . n 
A 1 310 TYR 310 310 310 TYR TYR A . n 
A 1 311 VAL 311 311 311 VAL VAL A . n 
A 1 312 LYS 312 312 312 LYS LYS A . n 
A 1 313 GLN 313 313 313 GLN GLN A . n 
A 1 314 ASN 314 314 314 ASN ASN A . n 
A 1 315 THR 315 315 315 THR THR A . n 
A 1 316 LEU 316 316 316 LEU LEU A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 LEU 318 318 318 LEU LEU A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 THR 320 320 320 THR THR A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 MET 322 322 322 MET MET A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 ASN 324 324 324 ASN ASN A . n 
A 1 325 VAL 325 325 325 VAL VAL A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 GLU 327 327 327 GLU GLU A . n 
A 1 328 LYS 328 328 ?   ?   ?   A . n 
A 1 329 GLN 329 329 ?   ?   ?   A . n 
A 1 330 THR 330 330 ?   ?   ?   A . n 
A 1 331 ARG 331 331 ?   ?   ?   A . n 
A 1 332 GLY 332 332 ?   ?   ?   A . n 
A 1 333 LEU 333 333 ?   ?   ?   A . n 
A 1 334 PHE 334 334 ?   ?   ?   A . n 
A 1 335 GLY 335 335 ?   ?   ?   A . n 
A 1 336 ALA 336 336 ?   ?   ?   A . n 
A 1 337 ILE 337 337 337 ILE ILE A . n 
A 1 338 ALA 338 338 338 ALA ALA A . n 
A 1 339 GLY 339 339 339 GLY GLY A . n 
A 1 340 PHE 340 340 340 PHE PHE A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 GLU 342 342 342 GLU GLU A . n 
A 1 343 ASN 343 343 343 ASN ASN A . n 
A 1 344 GLY 344 344 344 GLY GLY A . n 
A 1 345 TRP 345 345 345 TRP TRP A . n 
A 1 346 GLU 346 346 346 GLU GLU A . n 
A 1 347 GLY 347 347 347 GLY GLY A . n 
A 1 348 MET 348 348 348 MET MET A . n 
A 1 349 ILE 349 349 349 ILE ILE A . n 
A 1 350 ASP 350 350 350 ASP ASP A . n 
A 1 351 GLY 351 351 351 GLY GLY A . n 
A 1 352 TRP 352 352 352 TRP TRP A . n 
A 1 353 TYR 353 353 353 TYR TYR A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 PHE 355 355 355 PHE PHE A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 HIS 357 357 357 HIS HIS A . n 
A 1 358 GLN 358 358 358 GLN GLN A . n 
A 1 359 ASN 359 359 359 ASN ASN A . n 
A 1 360 SER 360 360 360 SER SER A . n 
A 1 361 GLU 361 361 361 GLU GLU A . n 
A 1 362 GLY 362 362 362 GLY GLY A . n 
A 1 363 THR 363 363 363 THR THR A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 GLN 365 365 365 GLN GLN A . n 
A 1 366 ALA 366 366 366 ALA ALA A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 ASP 368 368 368 ASP ASP A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 LYS 370 370 370 LYS LYS A . n 
A 1 371 SER 371 371 371 SER SER A . n 
A 1 372 THR 372 372 372 THR THR A . n 
A 1 373 GLN 373 373 373 GLN GLN A . n 
A 1 374 ALA 374 374 374 ALA ALA A . n 
A 1 375 ALA 375 375 375 ALA ALA A . n 
A 1 376 ILE 376 376 376 ILE ILE A . n 
A 1 377 ASP 377 377 377 ASP ASP A . n 
A 1 378 GLN 378 378 378 GLN GLN A . n 
A 1 379 ILE 379 379 379 ILE ILE A . n 
A 1 380 ASN 380 380 380 ASN ASN A . n 
A 1 381 GLY 381 381 381 GLY GLY A . n 
A 1 382 LYS 382 382 382 LYS LYS A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 ASN 384 384 384 ASN ASN A . n 
A 1 385 ARG 385 385 385 ARG ARG A . n 
A 1 386 VAL 386 386 386 VAL VAL A . n 
A 1 387 ILE 387 387 387 ILE ILE A . n 
A 1 388 GLU 388 388 388 GLU GLU A . n 
A 1 389 LYS 389 389 389 LYS LYS A . n 
A 1 390 THR 390 390 390 THR THR A . n 
A 1 391 ASN 391 391 391 ASN ASN A . n 
A 1 392 GLU 392 392 392 GLU GLU A . n 
A 1 393 LYS 393 393 393 LYS LYS A . n 
A 1 394 PHE 394 394 394 PHE PHE A . n 
A 1 395 HIS 395 395 395 HIS HIS A . n 
A 1 396 GLN 396 396 396 GLN GLN A . n 
A 1 397 ILE 397 397 397 ILE ILE A . n 
A 1 398 GLU 398 398 398 GLU GLU A . n 
A 1 399 LYS 399 399 399 LYS LYS A . n 
A 1 400 GLU 400 400 400 GLU GLU A . n 
A 1 401 PHE 401 401 401 PHE PHE A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 GLU 403 403 403 GLU GLU A . n 
A 1 404 VAL 404 404 404 VAL VAL A . n 
A 1 405 GLU 405 405 405 GLU GLU A . n 
A 1 406 GLY 406 406 406 GLY GLY A . n 
A 1 407 ARG 407 407 407 ARG ARG A . n 
A 1 408 ILE 408 408 408 ILE ILE A . n 
A 1 409 GLN 409 409 409 GLN GLN A . n 
A 1 410 ASP 410 410 410 ASP ASP A . n 
A 1 411 LEU 411 411 411 LEU LEU A . n 
A 1 412 GLU 412 412 412 GLU GLU A . n 
A 1 413 LYS 413 413 413 LYS LYS A . n 
A 1 414 TYR 414 414 414 TYR TYR A . n 
A 1 415 VAL 415 415 415 VAL VAL A . n 
A 1 416 GLU 416 416 416 GLU GLU A . n 
A 1 417 ASP 417 417 417 ASP ASP A . n 
A 1 418 THR 418 418 418 THR THR A . n 
A 1 419 LYS 419 419 419 LYS LYS A . n 
A 1 420 VAL 420 420 420 VAL VAL A . n 
A 1 421 ASP 421 421 421 ASP ASP A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 TRP 423 423 423 TRP TRP A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 TYR 425 425 425 TYR TYR A . n 
A 1 426 ASN 426 426 426 ASN ASN A . n 
A 1 427 ALA 427 427 427 ALA ALA A . n 
A 1 428 GLU 428 428 428 GLU GLU A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 LEU 430 430 430 LEU LEU A . n 
A 1 431 VAL 431 431 431 VAL VAL A . n 
A 1 432 ALA 432 432 432 ALA ALA A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 GLU 434 434 434 GLU GLU A . n 
A 1 435 ASN 435 435 435 ASN ASN A . n 
A 1 436 GLN 436 436 436 GLN GLN A . n 
A 1 437 HIS 437 437 437 HIS HIS A . n 
A 1 438 THR 438 438 438 THR THR A . n 
A 1 439 ILE 439 439 439 ILE ILE A . n 
A 1 440 ASP 440 440 440 ASP ASP A . n 
A 1 441 LEU 441 441 441 LEU LEU A . n 
A 1 442 THR 442 442 442 THR THR A . n 
A 1 443 ASP 443 443 443 ASP ASP A . n 
A 1 444 SER 444 444 444 SER SER A . n 
A 1 445 GLU 445 445 445 GLU GLU A . n 
A 1 446 MET 446 446 446 MET MET A . n 
A 1 447 ASN 447 447 447 ASN ASN A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 PHE 450 450 450 PHE PHE A . n 
A 1 451 GLU 451 451 451 GLU GLU A . n 
A 1 452 LYS 452 452 452 LYS LYS A . n 
A 1 453 THR 453 453 453 THR THR A . n 
A 1 454 ARG 454 454 454 ARG ARG A . n 
A 1 455 ARG 455 455 455 ARG ARG A . n 
A 1 456 GLN 456 456 456 GLN GLN A . n 
A 1 457 LEU 457 457 457 LEU LEU A . n 
A 1 458 ARG 458 458 458 ARG ARG A . n 
A 1 459 GLU 459 459 459 GLU GLU A . n 
A 1 460 ASN 460 460 460 ASN ASN A . n 
A 1 461 ALA 461 461 461 ALA ALA A . n 
A 1 462 GLU 462 462 462 GLU GLU A . n 
A 1 463 ASP 463 463 463 ASP ASP A . n 
A 1 464 MET 464 464 464 MET MET A . n 
A 1 465 GLY 465 465 465 GLY GLY A . n 
A 1 466 ASN 466 466 466 ASN ASN A . n 
A 1 467 GLY 467 467 467 GLY GLY A . n 
A 1 468 CYS 468 468 468 CYS CYS A . n 
A 1 469 PHE 469 469 469 PHE PHE A . n 
A 1 470 LYS 470 470 470 LYS LYS A . n 
A 1 471 ILE 471 471 471 ILE ILE A . n 
A 1 472 TYR 472 472 472 TYR TYR A . n 
A 1 473 HIS 473 473 473 HIS HIS A . n 
A 1 474 LYS 474 474 474 LYS LYS A . n 
A 1 475 CYS 475 475 475 CYS CYS A . n 
A 1 476 ASP 476 476 476 ASP ASP A . n 
A 1 477 ASN 477 477 477 ASN ASN A . n 
A 1 478 ALA 478 478 478 ALA ALA A . n 
A 1 479 CYS 479 479 479 CYS CYS A . n 
A 1 480 ILE 480 480 480 ILE ILE A . n 
A 1 481 GLU 481 481 481 GLU GLU A . n 
A 1 482 SER 482 482 482 SER SER A . n 
A 1 483 ILE 483 483 483 ILE ILE A . n 
A 1 484 ARG 484 484 484 ARG ARG A . n 
A 1 485 ASN 485 485 485 ASN ASN A . n 
A 1 486 GLY 486 486 486 GLY GLY A . n 
A 1 487 THR 487 487 487 THR THR A . n 
A 1 488 TYR 488 488 488 TYR TYR A . n 
A 1 489 ASP 489 489 489 ASP ASP A . n 
A 1 490 HIS 490 490 490 HIS HIS A . n 
A 1 491 ASP 491 491 491 ASP ASP A . n 
A 1 492 ILE 492 492 492 ILE ILE A . n 
A 1 493 TYR 493 493 493 TYR TYR A . n 
A 1 494 ARG 494 494 494 ARG ARG A . n 
A 1 495 ASP 495 495 495 ASP ASP A . n 
A 1 496 GLU 496 496 496 GLU GLU A . n 
A 1 497 ALA 497 497 497 ALA ALA A . n 
A 1 498 LEU 498 498 498 LEU LEU A . n 
A 1 499 ASN 499 499 499 ASN ASN A . n 
A 1 500 ASN 500 500 500 ASN ASN A . n 
A 1 501 ARG 501 501 501 ARG ARG A . n 
A 1 502 PHE 502 502 502 PHE PHE A . n 
B 1 1   LEU 1   1   ?   ?   ?   B . n 
B 1 2   GLN 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   ASN 4   4   ?   ?   ?   B . n 
B 1 5   LEU 5   5   ?   ?   ?   B . n 
B 1 6   PRO 6   6   ?   ?   ?   B . n 
B 1 7   GLY 7   7   ?   ?   ?   B . n 
B 1 8   LYS 8   8   ?   ?   ?   B . n 
B 1 9   ASP 9   9   ?   ?   ?   B . n 
B 1 10  SER 10  10  ?   ?   ?   B . n 
B 1 11  SER 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  12  THR THR B . n 
B 1 13  ALA 13  13  13  ALA ALA B . n 
B 1 14  THR 14  14  14  THR THR B . n 
B 1 15  LEU 15  15  15  LEU LEU B . n 
B 1 16  CYS 16  16  16  CYS CYS B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  GLY 18  18  18  GLY GLY B . n 
B 1 19  HIS 19  19  19  HIS HIS B . n 
B 1 20  HIS 20  20  20  HIS HIS B . n 
B 1 21  SER 21  21  21  SER SER B . n 
B 1 22  VAL 22  22  22  VAL VAL B . n 
B 1 23  PRO 23  23  23  PRO PRO B . n 
B 1 24  ASN 24  24  24  ASN ASN B . n 
B 1 25  GLY 25  25  25  GLY GLY B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  ILE 27  27  27  ILE ILE B . n 
B 1 28  VAL 28  28  28  VAL VAL B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  THR 30  30  30  THR THR B . n 
B 1 31  ILE 31  31  31  ILE ILE B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  ASP 33  33  33  ASP ASP B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  GLN 35  35  35  GLN GLN B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  GLU 37  37  37  GLU GLU B . n 
B 1 38  VAL 38  38  38  VAL VAL B . n 
B 1 39  THR 39  39  39  THR THR B . n 
B 1 40  ASN 40  40  40  ASN ASN B . n 
B 1 41  ALA 41  41  41  ALA ALA B . n 
B 1 42  THR 42  42  42  THR THR B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  LEU 44  44  44  LEU LEU B . n 
B 1 45  VAL 45  45  45  VAL VAL B . n 
B 1 46  GLN 46  46  46  GLN GLN B . n 
B 1 47  ASN 47  47  47  ASN ASN B . n 
B 1 48  SER 48  48  48  SER SER B . n 
B 1 49  SER 49  49  49  SER SER B . n 
B 1 50  THR 50  50  50  THR THR B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  LYS 52  52  52  LYS LYS B . n 
B 1 53  ILE 53  53  53  ILE ILE B . n 
B 1 54  CYS 54  54  54  CYS CYS B . n 
B 1 55  ASN 55  55  55  ASN ASN B . n 
B 1 56  ASN 56  56  56  ASN ASN B . n 
B 1 57  PRO 57  57  57  PRO PRO B . n 
B 1 58  HIS 58  58  58  HIS HIS B . n 
B 1 59  LYS 59  59  59  LYS LYS B . n 
B 1 60  VAL 60  60  60  VAL VAL B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  ASP 62  62  62  ASP ASP B . n 
B 1 63  GLY 63  63  63  GLY GLY B . n 
B 1 64  ARG 64  64  64  ARG ARG B . n 
B 1 65  ASP 65  65  65  ASP ASP B . n 
B 1 66  CYS 66  66  66  CYS CYS B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  ASP 70  70  70  ASP ASP B . n 
B 1 71  ALA 71  71  71  ALA ALA B . n 
B 1 72  MET 72  72  72  MET MET B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  GLY 74  74  74  GLY GLY B . n 
B 1 75  ASP 75  75  75  ASP ASP B . n 
B 1 76  PRO 76  76  76  PRO PRO B . n 
B 1 77  HIS 77  77  77  HIS HIS B . n 
B 1 78  CYS 78  78  78  CYS CYS B . n 
B 1 79  ASP 79  79  79  ASP ASP B . n 
B 1 80  VAL 80  80  80  VAL VAL B . n 
B 1 81  PHE 81  81  81  PHE PHE B . n 
B 1 82  GLN 82  82  82  GLN GLN B . n 
B 1 83  ASP 83  83  83  ASP ASP B . n 
B 1 84  GLU 84  84  84  GLU GLU B . n 
B 1 85  LYS 85  85  85  LYS LYS B . n 
B 1 86  TRP 86  86  86  TRP TRP B . n 
B 1 87  ASP 87  87  87  ASP ASP B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  PHE 89  89  89  PHE PHE B . n 
B 1 90  VAL 90  90  90  VAL VAL B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  ARG 92  92  92  ARG ARG B . n 
B 1 93  SER 93  93  93  SER SER B . n 
B 1 94  SER 94  94  94  SER SER B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  PHE 96  96  96  PHE PHE B . n 
B 1 97  SER 97  97  97  SER SER B . n 
B 1 98  ASN 98  98  98  ASN ASN B . n 
B 1 99  CYS 99  99  99  CYS CYS B . n 
B 1 100 TYR 100 100 100 TYR TYR B . n 
B 1 101 PRO 101 101 101 PRO PRO B . n 
B 1 102 TYR 102 102 102 TYR TYR B . n 
B 1 103 ASP 103 103 103 ASP ASP B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 PRO 105 105 105 PRO PRO B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 TYR 107 107 107 TYR TYR B . n 
B 1 108 ALA 108 108 108 ALA ALA B . n 
B 1 109 SER 109 109 109 SER SER B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 ARG 111 111 111 ARG ARG B . n 
B 1 112 SER 112 112 112 SER SER B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 ILE 114 114 114 ILE ILE B . n 
B 1 115 ALA 115 115 115 ALA ALA B . n 
B 1 116 SER 116 116 116 SER SER B . n 
B 1 117 SER 117 117 117 SER SER B . n 
B 1 118 GLY 118 118 118 GLY GLY B . n 
B 1 119 THR 119 119 119 THR THR B . n 
B 1 120 LEU 120 120 120 LEU LEU B . n 
B 1 121 ASP 121 121 121 ASP ASP B . n 
B 1 122 PHE 122 122 122 PHE PHE B . n 
B 1 123 ILE 123 123 123 ILE ILE B . n 
B 1 124 THR 124 124 124 THR THR B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 SER 126 126 126 SER SER B . n 
B 1 127 PHE 127 127 127 PHE PHE B . n 
B 1 128 THR 128 128 128 THR THR B . n 
B 1 129 TRP 129 129 129 TRP TRP B . n 
B 1 130 ALA 130 130 130 ALA ALA B . n 
B 1 131 GLY 131 131 131 GLY GLY B . n 
B 1 132 VAL 132 132 132 VAL VAL B . n 
B 1 133 SER 133 133 133 SER SER B . n 
B 1 134 GLN 134 134 134 GLN GLN B . n 
B 1 135 ASN 135 135 135 ASN ASN B . n 
B 1 136 GLY 136 136 136 GLY GLY B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 SER 138 138 138 SER SER B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 CYS 141 141 141 CYS CYS B . n 
B 1 142 LYS 142 142 142 LYS LYS B . n 
B 1 143 ARG 143 143 143 ARG ARG B . n 
B 1 144 GLY 144 144 144 GLY GLY B . n 
B 1 145 PRO 145 145 145 PRO PRO B . n 
B 1 146 ALA 146 146 146 ALA ALA B . n 
B 1 147 ASN 147 147 147 ASN ASN B . n 
B 1 148 GLY 148 148 148 GLY GLY B . n 
B 1 149 PHE 149 149 149 PHE PHE B . n 
B 1 150 PHE 150 150 150 PHE PHE B . n 
B 1 151 SER 151 151 151 SER SER B . n 
B 1 152 ARG 152 152 152 ARG ARG B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 ASN 154 154 154 ASN ASN B . n 
B 1 155 TRP 155 155 155 TRP TRP B . n 
B 1 156 LEU 156 156 156 LEU LEU B . n 
B 1 157 THR 157 157 157 THR THR B . n 
B 1 158 LYS 158 158 158 LYS LYS B . n 
B 1 159 SER 159 159 159 SER SER B . n 
B 1 160 GLY 160 160 160 GLY GLY B . n 
B 1 161 SER 161 161 161 SER SER B . n 
B 1 162 SER 162 162 162 SER SER B . n 
B 1 163 TYR 163 163 163 TYR TYR B . n 
B 1 164 PRO 164 164 164 PRO PRO B . n 
B 1 165 LEU 165 165 165 LEU LEU B . n 
B 1 166 LEU 166 166 166 LEU LEU B . n 
B 1 167 ASN 167 167 167 ASN ASN B . n 
B 1 168 VAL 168 168 168 VAL VAL B . n 
B 1 169 THR 169 169 169 THR THR B . n 
B 1 170 MET 170 170 170 MET MET B . n 
B 1 171 PRO 171 171 171 PRO PRO B . n 
B 1 172 ASN 172 172 172 ASN ASN B . n 
B 1 173 ASN 173 173 173 ASN ASN B . n 
B 1 174 TYR 174 174 174 TYR TYR B . n 
B 1 175 ASN 175 175 175 ASN ASN B . n 
B 1 176 PHE 176 176 176 PHE PHE B . n 
B 1 177 ASP 177 177 177 ASP ASP B . n 
B 1 178 LYS 178 178 178 LYS LYS B . n 
B 1 179 LEU 179 179 179 LEU LEU B . n 
B 1 180 TYR 180 180 180 TYR TYR B . n 
B 1 181 ILE 181 181 181 ILE ILE B . n 
B 1 182 TRP 182 182 182 TRP TRP B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 HIS 185 185 185 HIS HIS B . n 
B 1 186 HIS 186 186 186 HIS HIS B . n 
B 1 187 PRO 187 187 187 PRO PRO B . n 
B 1 188 SER 188 188 188 SER SER B . n 
B 1 189 THR 189 189 189 THR THR B . n 
B 1 190 ASN 190 190 190 ASN ASN B . n 
B 1 191 GLN 191 191 191 GLN GLN B . n 
B 1 192 GLU 192 192 192 GLU GLU B . n 
B 1 193 GLN 193 193 193 GLN GLN B . n 
B 1 194 THR 194 194 194 THR THR B . n 
B 1 195 ASN 195 195 195 ASN ASN B . n 
B 1 196 LEU 196 196 196 LEU LEU B . n 
B 1 197 TYR 197 197 197 TYR TYR B . n 
B 1 198 VAL 198 198 198 VAL VAL B . n 
B 1 199 GLN 199 199 199 GLN GLN B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 SER 201 201 201 SER SER B . n 
B 1 202 GLY 202 202 202 GLY GLY B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 THR 205 205 205 THR THR B . n 
B 1 206 VAL 206 206 206 VAL VAL B . n 
B 1 207 SER 207 207 207 SER SER B . n 
B 1 208 THR 208 208 208 THR THR B . n 
B 1 209 ARG 209 209 209 ARG ARG B . n 
B 1 210 ARG 210 210 210 ARG ARG B . n 
B 1 211 SER 211 211 211 SER SER B . n 
B 1 212 GLN 212 212 212 GLN GLN B . n 
B 1 213 GLN 213 213 213 GLN GLN B . n 
B 1 214 THR 214 214 214 THR THR B . n 
B 1 215 ILE 215 215 215 ILE ILE B . n 
B 1 216 VAL 216 216 216 VAL VAL B . n 
B 1 217 PRO 217 217 217 PRO PRO B . n 
B 1 218 ASN 218 218 218 ASN ASN B . n 
B 1 219 ILE 219 219 219 ILE ILE B . n 
B 1 220 GLY 220 220 220 GLY GLY B . n 
B 1 221 SER 221 221 221 SER SER B . n 
B 1 222 ARG 222 222 222 ARG ARG B . n 
B 1 223 PRO 223 223 223 PRO PRO B . n 
B 1 224 TRP 224 224 224 TRP TRP B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 ARG 226 226 226 ARG ARG B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 GLN 228 228 228 GLN GLN B . n 
B 1 229 SER 229 229 229 SER SER B . n 
B 1 230 SER 230 230 230 SER SER B . n 
B 1 231 ARG 231 231 231 ARG ARG B . n 
B 1 232 ILE 232 232 232 ILE ILE B . n 
B 1 233 SER 233 233 233 SER SER B . n 
B 1 234 ILE 234 234 234 ILE ILE B . n 
B 1 235 TYR 235 235 235 TYR TYR B . n 
B 1 236 TRP 236 236 236 TRP TRP B . n 
B 1 237 THR 237 237 237 THR THR B . n 
B 1 238 ILE 238 238 238 ILE ILE B . n 
B 1 239 VAL 239 239 239 VAL VAL B . n 
B 1 240 LYS 240 240 240 LYS LYS B . n 
B 1 241 PRO 241 241 241 PRO PRO B . n 
B 1 242 GLY 242 242 242 GLY GLY B . n 
B 1 243 ASP 243 243 243 ASP ASP B . n 
B 1 244 VAL 244 244 244 VAL VAL B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 ILE 247 247 247 ILE ILE B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 SER 249 249 249 SER SER B . n 
B 1 250 ASN 250 250 250 ASN ASN B . n 
B 1 251 GLY 251 251 251 GLY GLY B . n 
B 1 252 ASN 252 252 252 ASN ASN B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ILE 254 254 254 ILE ILE B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 PRO 256 256 256 PRO PRO B . n 
B 1 257 ARG 257 257 257 ARG ARG B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 PHE 259 259 259 PHE PHE B . n 
B 1 260 PHE 260 260 260 PHE PHE B . n 
B 1 261 LYS 261 261 261 LYS LYS B . n 
B 1 262 ILE 262 262 262 ILE ILE B . n 
B 1 263 ARG 263 263 263 ARG ARG B . n 
B 1 264 THR 264 264 264 THR THR B . n 
B 1 265 GLY 265 265 265 GLY GLY B . n 
B 1 266 ARG 266 266 266 ARG ARG B . n 
B 1 267 SER 267 267 267 SER SER B . n 
B 1 268 SER 268 268 268 SER SER B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 MET 270 270 270 MET MET B . n 
B 1 271 ARG 271 271 271 ARG ARG B . n 
B 1 272 SER 272 272 272 SER SER B . n 
B 1 273 ASP 273 273 273 ASP ASP B . n 
B 1 274 ALA 274 274 274 ALA ALA B . n 
B 1 275 PRO 275 275 275 PRO PRO B . n 
B 1 276 ILE 276 276 276 ILE ILE B . n 
B 1 277 GLU 277 277 277 GLU GLU B . n 
B 1 278 THR 278 278 278 THR THR B . n 
B 1 279 CYS 279 279 279 CYS CYS B . n 
B 1 280 ILE 280 280 280 ILE ILE B . n 
B 1 281 SER 281 281 281 SER SER B . n 
B 1 282 GLU 282 282 282 GLU GLU B . n 
B 1 283 CYS 283 283 283 CYS CYS B . n 
B 1 284 ILE 284 284 284 ILE ILE B . n 
B 1 285 THR 285 285 285 THR THR B . n 
B 1 286 PRO 286 286 286 PRO PRO B . n 
B 1 287 ASN 287 287 287 ASN ASN B . n 
B 1 288 GLY 288 288 288 GLY GLY B . n 
B 1 289 SER 289 289 289 SER SER B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 PRO 291 291 291 PRO PRO B . n 
B 1 292 ASN 292 292 292 ASN ASN B . n 
B 1 293 ASP 293 293 293 ASP ASP B . n 
B 1 294 LYS 294 294 294 LYS LYS B . n 
B 1 295 PRO 295 295 295 PRO PRO B . n 
B 1 296 PHE 296 296 296 PHE PHE B . n 
B 1 297 GLN 297 297 297 GLN GLN B . n 
B 1 298 ASN 298 298 298 ASN ASN B . n 
B 1 299 VAL 299 299 299 VAL VAL B . n 
B 1 300 ASN 300 300 300 ASN ASN B . n 
B 1 301 LYS 301 301 301 LYS LYS B . n 
B 1 302 ILE 302 302 302 ILE ILE B . n 
B 1 303 THR 303 303 303 THR THR B . n 
B 1 304 TYR 304 304 304 TYR TYR B . n 
B 1 305 GLY 305 305 305 GLY GLY B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 CYS 307 307 307 CYS CYS B . n 
B 1 308 PRO 308 308 308 PRO PRO B . n 
B 1 309 LYS 309 309 309 LYS LYS B . n 
B 1 310 TYR 310 310 310 TYR TYR B . n 
B 1 311 VAL 311 311 311 VAL VAL B . n 
B 1 312 LYS 312 312 312 LYS LYS B . n 
B 1 313 GLN 313 313 313 GLN GLN B . n 
B 1 314 ASN 314 314 314 ASN ASN B . n 
B 1 315 THR 315 315 315 THR THR B . n 
B 1 316 LEU 316 316 316 LEU LEU B . n 
B 1 317 LYS 317 317 317 LYS LYS B . n 
B 1 318 LEU 318 318 318 LEU LEU B . n 
B 1 319 ALA 319 319 319 ALA ALA B . n 
B 1 320 THR 320 320 320 THR THR B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 MET 322 322 322 MET MET B . n 
B 1 323 ARG 323 323 323 ARG ARG B . n 
B 1 324 ASN 324 324 324 ASN ASN B . n 
B 1 325 VAL 325 325 325 VAL VAL B . n 
B 1 326 PRO 326 326 326 PRO PRO B . n 
B 1 327 GLU 327 327 327 GLU GLU B . n 
B 1 328 LYS 328 328 328 LYS LYS B . n 
B 1 329 GLN 329 329 ?   ?   ?   B . n 
B 1 330 THR 330 330 ?   ?   ?   B . n 
B 1 331 ARG 331 331 ?   ?   ?   B . n 
B 1 332 GLY 332 332 ?   ?   ?   B . n 
B 1 333 LEU 333 333 ?   ?   ?   B . n 
B 1 334 PHE 334 334 ?   ?   ?   B . n 
B 1 335 GLY 335 335 ?   ?   ?   B . n 
B 1 336 ALA 336 336 336 ALA ALA B . n 
B 1 337 ILE 337 337 337 ILE ILE B . n 
B 1 338 ALA 338 338 338 ALA ALA B . n 
B 1 339 GLY 339 339 339 GLY GLY B . n 
B 1 340 PHE 340 340 340 PHE PHE B . n 
B 1 341 ILE 341 341 341 ILE ILE B . n 
B 1 342 GLU 342 342 342 GLU GLU B . n 
B 1 343 ASN 343 343 343 ASN ASN B . n 
B 1 344 GLY 344 344 344 GLY GLY B . n 
B 1 345 TRP 345 345 345 TRP TRP B . n 
B 1 346 GLU 346 346 346 GLU GLU B . n 
B 1 347 GLY 347 347 347 GLY GLY B . n 
B 1 348 MET 348 348 348 MET MET B . n 
B 1 349 ILE 349 349 349 ILE ILE B . n 
B 1 350 ASP 350 350 350 ASP ASP B . n 
B 1 351 GLY 351 351 351 GLY GLY B . n 
B 1 352 TRP 352 352 352 TRP TRP B . n 
B 1 353 TYR 353 353 353 TYR TYR B . n 
B 1 354 GLY 354 354 354 GLY GLY B . n 
B 1 355 PHE 355 355 355 PHE PHE B . n 
B 1 356 ARG 356 356 356 ARG ARG B . n 
B 1 357 HIS 357 357 357 HIS HIS B . n 
B 1 358 GLN 358 358 358 GLN GLN B . n 
B 1 359 ASN 359 359 359 ASN ASN B . n 
B 1 360 SER 360 360 360 SER SER B . n 
B 1 361 GLU 361 361 361 GLU GLU B . n 
B 1 362 GLY 362 362 362 GLY GLY B . n 
B 1 363 THR 363 363 363 THR THR B . n 
B 1 364 GLY 364 364 364 GLY GLY B . n 
B 1 365 GLN 365 365 365 GLN GLN B . n 
B 1 366 ALA 366 366 366 ALA ALA B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 ASP 368 368 368 ASP ASP B . n 
B 1 369 LEU 369 369 369 LEU LEU B . n 
B 1 370 LYS 370 370 370 LYS LYS B . n 
B 1 371 SER 371 371 371 SER SER B . n 
B 1 372 THR 372 372 372 THR THR B . n 
B 1 373 GLN 373 373 373 GLN GLN B . n 
B 1 374 ALA 374 374 374 ALA ALA B . n 
B 1 375 ALA 375 375 375 ALA ALA B . n 
B 1 376 ILE 376 376 376 ILE ILE B . n 
B 1 377 ASP 377 377 377 ASP ASP B . n 
B 1 378 GLN 378 378 378 GLN GLN B . n 
B 1 379 ILE 379 379 379 ILE ILE B . n 
B 1 380 ASN 380 380 380 ASN ASN B . n 
B 1 381 GLY 381 381 381 GLY GLY B . n 
B 1 382 LYS 382 382 382 LYS LYS B . n 
B 1 383 LEU 383 383 383 LEU LEU B . n 
B 1 384 ASN 384 384 384 ASN ASN B . n 
B 1 385 ARG 385 385 385 ARG ARG B . n 
B 1 386 VAL 386 386 386 VAL VAL B . n 
B 1 387 ILE 387 387 387 ILE ILE B . n 
B 1 388 GLU 388 388 388 GLU GLU B . n 
B 1 389 LYS 389 389 389 LYS LYS B . n 
B 1 390 THR 390 390 390 THR THR B . n 
B 1 391 ASN 391 391 391 ASN ASN B . n 
B 1 392 GLU 392 392 392 GLU GLU B . n 
B 1 393 LYS 393 393 393 LYS LYS B . n 
B 1 394 PHE 394 394 394 PHE PHE B . n 
B 1 395 HIS 395 395 395 HIS HIS B . n 
B 1 396 GLN 396 396 396 GLN GLN B . n 
B 1 397 ILE 397 397 397 ILE ILE B . n 
B 1 398 GLU 398 398 398 GLU GLU B . n 
B 1 399 LYS 399 399 399 LYS LYS B . n 
B 1 400 GLU 400 400 400 GLU GLU B . n 
B 1 401 PHE 401 401 401 PHE PHE B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 GLU 403 403 403 GLU GLU B . n 
B 1 404 VAL 404 404 404 VAL VAL B . n 
B 1 405 GLU 405 405 405 GLU GLU B . n 
B 1 406 GLY 406 406 406 GLY GLY B . n 
B 1 407 ARG 407 407 407 ARG ARG B . n 
B 1 408 ILE 408 408 408 ILE ILE B . n 
B 1 409 GLN 409 409 409 GLN GLN B . n 
B 1 410 ASP 410 410 410 ASP ASP B . n 
B 1 411 LEU 411 411 411 LEU LEU B . n 
B 1 412 GLU 412 412 412 GLU GLU B . n 
B 1 413 LYS 413 413 413 LYS LYS B . n 
B 1 414 TYR 414 414 414 TYR TYR B . n 
B 1 415 VAL 415 415 415 VAL VAL B . n 
B 1 416 GLU 416 416 416 GLU GLU B . n 
B 1 417 ASP 417 417 417 ASP ASP B . n 
B 1 418 THR 418 418 418 THR THR B . n 
B 1 419 LYS 419 419 419 LYS LYS B . n 
B 1 420 VAL 420 420 420 VAL VAL B . n 
B 1 421 ASP 421 421 421 ASP ASP B . n 
B 1 422 LEU 422 422 422 LEU LEU B . n 
B 1 423 TRP 423 423 423 TRP TRP B . n 
B 1 424 SER 424 424 424 SER SER B . n 
B 1 425 TYR 425 425 425 TYR TYR B . n 
B 1 426 ASN 426 426 426 ASN ASN B . n 
B 1 427 ALA 427 427 427 ALA ALA B . n 
B 1 428 GLU 428 428 428 GLU GLU B . n 
B 1 429 LEU 429 429 429 LEU LEU B . n 
B 1 430 LEU 430 430 430 LEU LEU B . n 
B 1 431 VAL 431 431 431 VAL VAL B . n 
B 1 432 ALA 432 432 432 ALA ALA B . n 
B 1 433 LEU 433 433 433 LEU LEU B . n 
B 1 434 GLU 434 434 434 GLU GLU B . n 
B 1 435 ASN 435 435 435 ASN ASN B . n 
B 1 436 GLN 436 436 436 GLN GLN B . n 
B 1 437 HIS 437 437 437 HIS HIS B . n 
B 1 438 THR 438 438 438 THR THR B . n 
B 1 439 ILE 439 439 439 ILE ILE B . n 
B 1 440 ASP 440 440 440 ASP ASP B . n 
B 1 441 LEU 441 441 441 LEU LEU B . n 
B 1 442 THR 442 442 442 THR THR B . n 
B 1 443 ASP 443 443 443 ASP ASP B . n 
B 1 444 SER 444 444 444 SER SER B . n 
B 1 445 GLU 445 445 445 GLU GLU B . n 
B 1 446 MET 446 446 446 MET MET B . n 
B 1 447 ASN 447 447 447 ASN ASN B . n 
B 1 448 LYS 448 448 448 LYS LYS B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 PHE 450 450 450 PHE PHE B . n 
B 1 451 GLU 451 451 451 GLU GLU B . n 
B 1 452 LYS 452 452 452 LYS LYS B . n 
B 1 453 THR 453 453 453 THR THR B . n 
B 1 454 ARG 454 454 454 ARG ARG B . n 
B 1 455 ARG 455 455 455 ARG ARG B . n 
B 1 456 GLN 456 456 456 GLN GLN B . n 
B 1 457 LEU 457 457 457 LEU LEU B . n 
B 1 458 ARG 458 458 458 ARG ARG B . n 
B 1 459 GLU 459 459 459 GLU GLU B . n 
B 1 460 ASN 460 460 460 ASN ASN B . n 
B 1 461 ALA 461 461 461 ALA ALA B . n 
B 1 462 GLU 462 462 462 GLU GLU B . n 
B 1 463 ASP 463 463 463 ASP ASP B . n 
B 1 464 MET 464 464 464 MET MET B . n 
B 1 465 GLY 465 465 465 GLY GLY B . n 
B 1 466 ASN 466 466 466 ASN ASN B . n 
B 1 467 GLY 467 467 467 GLY GLY B . n 
B 1 468 CYS 468 468 468 CYS CYS B . n 
B 1 469 PHE 469 469 469 PHE PHE B . n 
B 1 470 LYS 470 470 470 LYS LYS B . n 
B 1 471 ILE 471 471 471 ILE ILE B . n 
B 1 472 TYR 472 472 472 TYR TYR B . n 
B 1 473 HIS 473 473 473 HIS HIS B . n 
B 1 474 LYS 474 474 474 LYS LYS B . n 
B 1 475 CYS 475 475 475 CYS CYS B . n 
B 1 476 ASP 476 476 476 ASP ASP B . n 
B 1 477 ASN 477 477 477 ASN ASN B . n 
B 1 478 ALA 478 478 478 ALA ALA B . n 
B 1 479 CYS 479 479 479 CYS CYS B . n 
B 1 480 ILE 480 480 480 ILE ILE B . n 
B 1 481 GLU 481 481 481 GLU GLU B . n 
B 1 482 SER 482 482 482 SER SER B . n 
B 1 483 ILE 483 483 483 ILE ILE B . n 
B 1 484 ARG 484 484 484 ARG ARG B . n 
B 1 485 ASN 485 485 485 ASN ASN B . n 
B 1 486 GLY 486 486 486 GLY GLY B . n 
B 1 487 THR 487 487 487 THR THR B . n 
B 1 488 TYR 488 488 488 TYR TYR B . n 
B 1 489 ASP 489 489 489 ASP ASP B . n 
B 1 490 HIS 490 490 490 HIS HIS B . n 
B 1 491 ASP 491 491 491 ASP ASP B . n 
B 1 492 ILE 492 492 492 ILE ILE B . n 
B 1 493 TYR 493 493 493 TYR TYR B . n 
B 1 494 ARG 494 494 494 ARG ARG B . n 
B 1 495 ASP 495 495 495 ASP ASP B . n 
B 1 496 GLU 496 496 496 GLU GLU B . n 
B 1 497 ALA 497 497 497 ALA ALA B . n 
B 1 498 LEU 498 498 498 LEU LEU B . n 
B 1 499 ASN 499 499 499 ASN ASN B . n 
B 1 500 ASN 500 500 500 ASN ASN B . n 
B 1 501 ARG 501 501 501 ARG ARG B . n 
B 1 502 PHE 502 502 502 PHE PHE B . n 
C 1 1   LEU 1   1   ?   ?   ?   C . n 
C 1 2   GLN 2   2   ?   ?   ?   C . n 
C 1 3   GLN 3   3   ?   ?   ?   C . n 
C 1 4   ASN 4   4   ?   ?   ?   C . n 
C 1 5   LEU 5   5   ?   ?   ?   C . n 
C 1 6   PRO 6   6   ?   ?   ?   C . n 
C 1 7   GLY 7   7   ?   ?   ?   C . n 
C 1 8   LYS 8   8   ?   ?   ?   C . n 
C 1 9   ASP 9   9   ?   ?   ?   C . n 
C 1 10  SER 10  10  ?   ?   ?   C . n 
C 1 11  SER 11  11  ?   ?   ?   C . n 
C 1 12  THR 12  12  12  THR THR C . n 
C 1 13  ALA 13  13  13  ALA ALA C . n 
C 1 14  THR 14  14  14  THR THR C . n 
C 1 15  LEU 15  15  15  LEU LEU C . n 
C 1 16  CYS 16  16  16  CYS CYS C . n 
C 1 17  LEU 17  17  17  LEU LEU C . n 
C 1 18  GLY 18  18  18  GLY GLY C . n 
C 1 19  HIS 19  19  19  HIS HIS C . n 
C 1 20  HIS 20  20  20  HIS HIS C . n 
C 1 21  SER 21  21  21  SER SER C . n 
C 1 22  VAL 22  22  22  VAL VAL C . n 
C 1 23  PRO 23  23  23  PRO PRO C . n 
C 1 24  ASN 24  24  24  ASN ASN C . n 
C 1 25  GLY 25  25  25  GLY GLY C . n 
C 1 26  THR 26  26  26  THR THR C . n 
C 1 27  ILE 27  27  27  ILE ILE C . n 
C 1 28  VAL 28  28  28  VAL VAL C . n 
C 1 29  LYS 29  29  29  LYS LYS C . n 
C 1 30  THR 30  30  30  THR THR C . n 
C 1 31  ILE 31  31  31  ILE ILE C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  ASP 33  33  33  ASP ASP C . n 
C 1 34  ASP 34  34  34  ASP ASP C . n 
C 1 35  GLN 35  35  35  GLN GLN C . n 
C 1 36  ILE 36  36  36  ILE ILE C . n 
C 1 37  GLU 37  37  37  GLU GLU C . n 
C 1 38  VAL 38  38  38  VAL VAL C . n 
C 1 39  THR 39  39  39  THR THR C . n 
C 1 40  ASN 40  40  40  ASN ASN C . n 
C 1 41  ALA 41  41  41  ALA ALA C . n 
C 1 42  THR 42  42  42  THR THR C . n 
C 1 43  GLU 43  43  43  GLU GLU C . n 
C 1 44  LEU 44  44  44  LEU LEU C . n 
C 1 45  VAL 45  45  45  VAL VAL C . n 
C 1 46  GLN 46  46  46  GLN GLN C . n 
C 1 47  ASN 47  47  47  ASN ASN C . n 
C 1 48  SER 48  48  48  SER SER C . n 
C 1 49  SER 49  49  49  SER SER C . n 
C 1 50  THR 50  50  50  THR THR C . n 
C 1 51  GLY 51  51  51  GLY GLY C . n 
C 1 52  LYS 52  52  52  LYS LYS C . n 
C 1 53  ILE 53  53  53  ILE ILE C . n 
C 1 54  CYS 54  54  54  CYS CYS C . n 
C 1 55  ASN 55  55  55  ASN ASN C . n 
C 1 56  ASN 56  56  56  ASN ASN C . n 
C 1 57  PRO 57  57  57  PRO PRO C . n 
C 1 58  HIS 58  58  58  HIS HIS C . n 
C 1 59  LYS 59  59  59  LYS LYS C . n 
C 1 60  VAL 60  60  60  VAL VAL C . n 
C 1 61  LEU 61  61  61  LEU LEU C . n 
C 1 62  ASP 62  62  62  ASP ASP C . n 
C 1 63  GLY 63  63  63  GLY GLY C . n 
C 1 64  ARG 64  64  64  ARG ARG C . n 
C 1 65  ASP 65  65  65  ASP ASP C . n 
C 1 66  CYS 66  66  66  CYS CYS C . n 
C 1 67  THR 67  67  67  THR THR C . n 
C 1 68  LEU 68  68  68  LEU LEU C . n 
C 1 69  ILE 69  69  69  ILE ILE C . n 
C 1 70  ASP 70  70  70  ASP ASP C . n 
C 1 71  ALA 71  71  71  ALA ALA C . n 
C 1 72  MET 72  72  72  MET MET C . n 
C 1 73  LEU 73  73  73  LEU LEU C . n 
C 1 74  GLY 74  74  74  GLY GLY C . n 
C 1 75  ASP 75  75  75  ASP ASP C . n 
C 1 76  PRO 76  76  76  PRO PRO C . n 
C 1 77  HIS 77  77  77  HIS HIS C . n 
C 1 78  CYS 78  78  78  CYS CYS C . n 
C 1 79  ASP 79  79  79  ASP ASP C . n 
C 1 80  VAL 80  80  80  VAL VAL C . n 
C 1 81  PHE 81  81  81  PHE PHE C . n 
C 1 82  GLN 82  82  82  GLN GLN C . n 
C 1 83  ASP 83  83  83  ASP ASP C . n 
C 1 84  GLU 84  84  84  GLU GLU C . n 
C 1 85  LYS 85  85  85  LYS LYS C . n 
C 1 86  TRP 86  86  86  TRP TRP C . n 
C 1 87  ASP 87  87  87  ASP ASP C . n 
C 1 88  LEU 88  88  88  LEU LEU C . n 
C 1 89  PHE 89  89  89  PHE PHE C . n 
C 1 90  VAL 90  90  90  VAL VAL C . n 
C 1 91  GLU 91  91  91  GLU GLU C . n 
C 1 92  ARG 92  92  92  ARG ARG C . n 
C 1 93  SER 93  93  93  SER SER C . n 
C 1 94  SER 94  94  94  SER SER C . n 
C 1 95  ALA 95  95  95  ALA ALA C . n 
C 1 96  PHE 96  96  96  PHE PHE C . n 
C 1 97  SER 97  97  97  SER SER C . n 
C 1 98  ASN 98  98  98  ASN ASN C . n 
C 1 99  CYS 99  99  99  CYS CYS C . n 
C 1 100 TYR 100 100 100 TYR TYR C . n 
C 1 101 PRO 101 101 101 PRO PRO C . n 
C 1 102 TYR 102 102 102 TYR TYR C . n 
C 1 103 ASP 103 103 103 ASP ASP C . n 
C 1 104 VAL 104 104 104 VAL VAL C . n 
C 1 105 PRO 105 105 105 PRO PRO C . n 
C 1 106 ASP 106 106 106 ASP ASP C . n 
C 1 107 TYR 107 107 107 TYR TYR C . n 
C 1 108 ALA 108 108 108 ALA ALA C . n 
C 1 109 SER 109 109 109 SER SER C . n 
C 1 110 LEU 110 110 110 LEU LEU C . n 
C 1 111 ARG 111 111 111 ARG ARG C . n 
C 1 112 SER 112 112 112 SER SER C . n 
C 1 113 LEU 113 113 113 LEU LEU C . n 
C 1 114 ILE 114 114 114 ILE ILE C . n 
C 1 115 ALA 115 115 115 ALA ALA C . n 
C 1 116 SER 116 116 116 SER SER C . n 
C 1 117 SER 117 117 117 SER SER C . n 
C 1 118 GLY 118 118 118 GLY GLY C . n 
C 1 119 THR 119 119 119 THR THR C . n 
C 1 120 LEU 120 120 120 LEU LEU C . n 
C 1 121 ASP 121 121 121 ASP ASP C . n 
C 1 122 PHE 122 122 122 PHE PHE C . n 
C 1 123 ILE 123 123 123 ILE ILE C . n 
C 1 124 THR 124 124 124 THR THR C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 SER 126 126 126 SER SER C . n 
C 1 127 PHE 127 127 127 PHE PHE C . n 
C 1 128 THR 128 128 128 THR THR C . n 
C 1 129 TRP 129 129 129 TRP TRP C . n 
C 1 130 ALA 130 130 130 ALA ALA C . n 
C 1 131 GLY 131 131 131 GLY GLY C . n 
C 1 132 VAL 132 132 132 VAL VAL C . n 
C 1 133 SER 133 133 133 SER SER C . n 
C 1 134 GLN 134 134 134 GLN GLN C . n 
C 1 135 ASN 135 135 135 ASN ASN C . n 
C 1 136 GLY 136 136 136 GLY GLY C . n 
C 1 137 GLY 137 137 137 GLY GLY C . n 
C 1 138 SER 138 138 138 SER SER C . n 
C 1 139 SER 139 139 139 SER SER C . n 
C 1 140 ALA 140 140 140 ALA ALA C . n 
C 1 141 CYS 141 141 141 CYS CYS C . n 
C 1 142 LYS 142 142 142 LYS LYS C . n 
C 1 143 ARG 143 143 143 ARG ARG C . n 
C 1 144 GLY 144 144 144 GLY GLY C . n 
C 1 145 PRO 145 145 145 PRO PRO C . n 
C 1 146 ALA 146 146 146 ALA ALA C . n 
C 1 147 ASN 147 147 147 ASN ASN C . n 
C 1 148 GLY 148 148 148 GLY GLY C . n 
C 1 149 PHE 149 149 149 PHE PHE C . n 
C 1 150 PHE 150 150 150 PHE PHE C . n 
C 1 151 SER 151 151 151 SER SER C . n 
C 1 152 ARG 152 152 152 ARG ARG C . n 
C 1 153 LEU 153 153 153 LEU LEU C . n 
C 1 154 ASN 154 154 154 ASN ASN C . n 
C 1 155 TRP 155 155 155 TRP TRP C . n 
C 1 156 LEU 156 156 156 LEU LEU C . n 
C 1 157 THR 157 157 157 THR THR C . n 
C 1 158 LYS 158 158 158 LYS LYS C . n 
C 1 159 SER 159 159 159 SER SER C . n 
C 1 160 GLY 160 160 160 GLY GLY C . n 
C 1 161 SER 161 161 161 SER SER C . n 
C 1 162 SER 162 162 162 SER SER C . n 
C 1 163 TYR 163 163 163 TYR TYR C . n 
C 1 164 PRO 164 164 164 PRO PRO C . n 
C 1 165 LEU 165 165 165 LEU LEU C . n 
C 1 166 LEU 166 166 166 LEU LEU C . n 
C 1 167 ASN 167 167 167 ASN ASN C . n 
C 1 168 VAL 168 168 168 VAL VAL C . n 
C 1 169 THR 169 169 169 THR THR C . n 
C 1 170 MET 170 170 170 MET MET C . n 
C 1 171 PRO 171 171 171 PRO PRO C . n 
C 1 172 ASN 172 172 172 ASN ASN C . n 
C 1 173 ASN 173 173 173 ASN ASN C . n 
C 1 174 TYR 174 174 174 TYR TYR C . n 
C 1 175 ASN 175 175 175 ASN ASN C . n 
C 1 176 PHE 176 176 176 PHE PHE C . n 
C 1 177 ASP 177 177 177 ASP ASP C . n 
C 1 178 LYS 178 178 178 LYS LYS C . n 
C 1 179 LEU 179 179 179 LEU LEU C . n 
C 1 180 TYR 180 180 180 TYR TYR C . n 
C 1 181 ILE 181 181 181 ILE ILE C . n 
C 1 182 TRP 182 182 182 TRP TRP C . n 
C 1 183 GLY 183 183 183 GLY GLY C . n 
C 1 184 VAL 184 184 184 VAL VAL C . n 
C 1 185 HIS 185 185 185 HIS HIS C . n 
C 1 186 HIS 186 186 186 HIS HIS C . n 
C 1 187 PRO 187 187 187 PRO PRO C . n 
C 1 188 SER 188 188 188 SER SER C . n 
C 1 189 THR 189 189 189 THR THR C . n 
C 1 190 ASN 190 190 190 ASN ASN C . n 
C 1 191 GLN 191 191 191 GLN GLN C . n 
C 1 192 GLU 192 192 192 GLU GLU C . n 
C 1 193 GLN 193 193 193 GLN GLN C . n 
C 1 194 THR 194 194 194 THR THR C . n 
C 1 195 ASN 195 195 195 ASN ASN C . n 
C 1 196 LEU 196 196 196 LEU LEU C . n 
C 1 197 TYR 197 197 197 TYR TYR C . n 
C 1 198 VAL 198 198 198 VAL VAL C . n 
C 1 199 GLN 199 199 199 GLN GLN C . n 
C 1 200 ALA 200 200 200 ALA ALA C . n 
C 1 201 SER 201 201 201 SER SER C . n 
C 1 202 GLY 202 202 202 GLY GLY C . n 
C 1 203 ARG 203 203 203 ARG ARG C . n 
C 1 204 VAL 204 204 204 VAL VAL C . n 
C 1 205 THR 205 205 205 THR THR C . n 
C 1 206 VAL 206 206 206 VAL VAL C . n 
C 1 207 SER 207 207 207 SER SER C . n 
C 1 208 THR 208 208 208 THR THR C . n 
C 1 209 ARG 209 209 209 ARG ARG C . n 
C 1 210 ARG 210 210 210 ARG ARG C . n 
C 1 211 SER 211 211 211 SER SER C . n 
C 1 212 GLN 212 212 212 GLN GLN C . n 
C 1 213 GLN 213 213 213 GLN GLN C . n 
C 1 214 THR 214 214 214 THR THR C . n 
C 1 215 ILE 215 215 215 ILE ILE C . n 
C 1 216 VAL 216 216 216 VAL VAL C . n 
C 1 217 PRO 217 217 217 PRO PRO C . n 
C 1 218 ASN 218 218 218 ASN ASN C . n 
C 1 219 ILE 219 219 219 ILE ILE C . n 
C 1 220 GLY 220 220 220 GLY GLY C . n 
C 1 221 SER 221 221 221 SER SER C . n 
C 1 222 ARG 222 222 222 ARG ARG C . n 
C 1 223 PRO 223 223 223 PRO PRO C . n 
C 1 224 TRP 224 224 224 TRP TRP C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 ARG 226 226 226 ARG ARG C . n 
C 1 227 GLY 227 227 227 GLY GLY C . n 
C 1 228 GLN 228 228 228 GLN GLN C . n 
C 1 229 SER 229 229 229 SER SER C . n 
C 1 230 SER 230 230 230 SER SER C . n 
C 1 231 ARG 231 231 231 ARG ARG C . n 
C 1 232 ILE 232 232 232 ILE ILE C . n 
C 1 233 SER 233 233 233 SER SER C . n 
C 1 234 ILE 234 234 234 ILE ILE C . n 
C 1 235 TYR 235 235 235 TYR TYR C . n 
C 1 236 TRP 236 236 236 TRP TRP C . n 
C 1 237 THR 237 237 237 THR THR C . n 
C 1 238 ILE 238 238 238 ILE ILE C . n 
C 1 239 VAL 239 239 239 VAL VAL C . n 
C 1 240 LYS 240 240 240 LYS LYS C . n 
C 1 241 PRO 241 241 241 PRO PRO C . n 
C 1 242 GLY 242 242 242 GLY GLY C . n 
C 1 243 ASP 243 243 243 ASP ASP C . n 
C 1 244 VAL 244 244 244 VAL VAL C . n 
C 1 245 LEU 245 245 245 LEU LEU C . n 
C 1 246 VAL 246 246 246 VAL VAL C . n 
C 1 247 ILE 247 247 247 ILE ILE C . n 
C 1 248 ASN 248 248 248 ASN ASN C . n 
C 1 249 SER 249 249 249 SER SER C . n 
C 1 250 ASN 250 250 250 ASN ASN C . n 
C 1 251 GLY 251 251 251 GLY GLY C . n 
C 1 252 ASN 252 252 252 ASN ASN C . n 
C 1 253 LEU 253 253 253 LEU LEU C . n 
C 1 254 ILE 254 254 254 ILE ILE C . n 
C 1 255 ALA 255 255 255 ALA ALA C . n 
C 1 256 PRO 256 256 256 PRO PRO C . n 
C 1 257 ARG 257 257 257 ARG ARG C . n 
C 1 258 GLY 258 258 258 GLY GLY C . n 
C 1 259 PHE 259 259 259 PHE PHE C . n 
C 1 260 PHE 260 260 260 PHE PHE C . n 
C 1 261 LYS 261 261 261 LYS LYS C . n 
C 1 262 ILE 262 262 262 ILE ILE C . n 
C 1 263 ARG 263 263 263 ARG ARG C . n 
C 1 264 THR 264 264 264 THR THR C . n 
C 1 265 GLY 265 265 265 GLY GLY C . n 
C 1 266 ARG 266 266 266 ARG ARG C . n 
C 1 267 SER 267 267 267 SER SER C . n 
C 1 268 SER 268 268 268 SER SER C . n 
C 1 269 ILE 269 269 269 ILE ILE C . n 
C 1 270 MET 270 270 270 MET MET C . n 
C 1 271 ARG 271 271 271 ARG ARG C . n 
C 1 272 SER 272 272 272 SER SER C . n 
C 1 273 ASP 273 273 273 ASP ASP C . n 
C 1 274 ALA 274 274 274 ALA ALA C . n 
C 1 275 PRO 275 275 275 PRO PRO C . n 
C 1 276 ILE 276 276 276 ILE ILE C . n 
C 1 277 GLU 277 277 277 GLU GLU C . n 
C 1 278 THR 278 278 278 THR THR C . n 
C 1 279 CYS 279 279 279 CYS CYS C . n 
C 1 280 ILE 280 280 280 ILE ILE C . n 
C 1 281 SER 281 281 281 SER SER C . n 
C 1 282 GLU 282 282 282 GLU GLU C . n 
C 1 283 CYS 283 283 283 CYS CYS C . n 
C 1 284 ILE 284 284 284 ILE ILE C . n 
C 1 285 THR 285 285 285 THR THR C . n 
C 1 286 PRO 286 286 286 PRO PRO C . n 
C 1 287 ASN 287 287 287 ASN ASN C . n 
C 1 288 GLY 288 288 288 GLY GLY C . n 
C 1 289 SER 289 289 289 SER SER C . n 
C 1 290 ILE 290 290 290 ILE ILE C . n 
C 1 291 PRO 291 291 291 PRO PRO C . n 
C 1 292 ASN 292 292 292 ASN ASN C . n 
C 1 293 ASP 293 293 293 ASP ASP C . n 
C 1 294 LYS 294 294 294 LYS LYS C . n 
C 1 295 PRO 295 295 295 PRO PRO C . n 
C 1 296 PHE 296 296 296 PHE PHE C . n 
C 1 297 GLN 297 297 297 GLN GLN C . n 
C 1 298 ASN 298 298 298 ASN ASN C . n 
C 1 299 VAL 299 299 299 VAL VAL C . n 
C 1 300 ASN 300 300 300 ASN ASN C . n 
C 1 301 LYS 301 301 301 LYS LYS C . n 
C 1 302 ILE 302 302 302 ILE ILE C . n 
C 1 303 THR 303 303 303 THR THR C . n 
C 1 304 TYR 304 304 304 TYR TYR C . n 
C 1 305 GLY 305 305 305 GLY GLY C . n 
C 1 306 ALA 306 306 306 ALA ALA C . n 
C 1 307 CYS 307 307 307 CYS CYS C . n 
C 1 308 PRO 308 308 308 PRO PRO C . n 
C 1 309 LYS 309 309 309 LYS LYS C . n 
C 1 310 TYR 310 310 310 TYR TYR C . n 
C 1 311 VAL 311 311 311 VAL VAL C . n 
C 1 312 LYS 312 312 312 LYS LYS C . n 
C 1 313 GLN 313 313 313 GLN GLN C . n 
C 1 314 ASN 314 314 314 ASN ASN C . n 
C 1 315 THR 315 315 315 THR THR C . n 
C 1 316 LEU 316 316 316 LEU LEU C . n 
C 1 317 LYS 317 317 317 LYS LYS C . n 
C 1 318 LEU 318 318 318 LEU LEU C . n 
C 1 319 ALA 319 319 319 ALA ALA C . n 
C 1 320 THR 320 320 320 THR THR C . n 
C 1 321 GLY 321 321 321 GLY GLY C . n 
C 1 322 MET 322 322 322 MET MET C . n 
C 1 323 ARG 323 323 323 ARG ARG C . n 
C 1 324 ASN 324 324 324 ASN ASN C . n 
C 1 325 VAL 325 325 325 VAL VAL C . n 
C 1 326 PRO 326 326 326 PRO PRO C . n 
C 1 327 GLU 327 327 327 GLU GLU C . n 
C 1 328 LYS 328 328 ?   ?   ?   C . n 
C 1 329 GLN 329 329 ?   ?   ?   C . n 
C 1 330 THR 330 330 ?   ?   ?   C . n 
C 1 331 ARG 331 331 ?   ?   ?   C . n 
C 1 332 GLY 332 332 ?   ?   ?   C . n 
C 1 333 LEU 333 333 ?   ?   ?   C . n 
C 1 334 PHE 334 334 ?   ?   ?   C . n 
C 1 335 GLY 335 335 ?   ?   ?   C . n 
C 1 336 ALA 336 336 ?   ?   ?   C . n 
C 1 337 ILE 337 337 337 ILE ILE C . n 
C 1 338 ALA 338 338 338 ALA ALA C . n 
C 1 339 GLY 339 339 339 GLY GLY C . n 
C 1 340 PHE 340 340 340 PHE PHE C . n 
C 1 341 ILE 341 341 341 ILE ILE C . n 
C 1 342 GLU 342 342 342 GLU GLU C . n 
C 1 343 ASN 343 343 343 ASN ASN C . n 
C 1 344 GLY 344 344 344 GLY GLY C . n 
C 1 345 TRP 345 345 345 TRP TRP C . n 
C 1 346 GLU 346 346 346 GLU GLU C . n 
C 1 347 GLY 347 347 347 GLY GLY C . n 
C 1 348 MET 348 348 348 MET MET C . n 
C 1 349 ILE 349 349 349 ILE ILE C . n 
C 1 350 ASP 350 350 350 ASP ASP C . n 
C 1 351 GLY 351 351 351 GLY GLY C . n 
C 1 352 TRP 352 352 352 TRP TRP C . n 
C 1 353 TYR 353 353 353 TYR TYR C . n 
C 1 354 GLY 354 354 354 GLY GLY C . n 
C 1 355 PHE 355 355 355 PHE PHE C . n 
C 1 356 ARG 356 356 356 ARG ARG C . n 
C 1 357 HIS 357 357 357 HIS HIS C . n 
C 1 358 GLN 358 358 358 GLN GLN C . n 
C 1 359 ASN 359 359 359 ASN ASN C . n 
C 1 360 SER 360 360 360 SER SER C . n 
C 1 361 GLU 361 361 361 GLU GLU C . n 
C 1 362 GLY 362 362 362 GLY GLY C . n 
C 1 363 THR 363 363 363 THR THR C . n 
C 1 364 GLY 364 364 364 GLY GLY C . n 
C 1 365 GLN 365 365 365 GLN GLN C . n 
C 1 366 ALA 366 366 366 ALA ALA C . n 
C 1 367 ALA 367 367 367 ALA ALA C . n 
C 1 368 ASP 368 368 368 ASP ASP C . n 
C 1 369 LEU 369 369 369 LEU LEU C . n 
C 1 370 LYS 370 370 370 LYS LYS C . n 
C 1 371 SER 371 371 371 SER SER C . n 
C 1 372 THR 372 372 372 THR THR C . n 
C 1 373 GLN 373 373 373 GLN GLN C . n 
C 1 374 ALA 374 374 374 ALA ALA C . n 
C 1 375 ALA 375 375 375 ALA ALA C . n 
C 1 376 ILE 376 376 376 ILE ILE C . n 
C 1 377 ASP 377 377 377 ASP ASP C . n 
C 1 378 GLN 378 378 378 GLN GLN C . n 
C 1 379 ILE 379 379 379 ILE ILE C . n 
C 1 380 ASN 380 380 380 ASN ASN C . n 
C 1 381 GLY 381 381 381 GLY GLY C . n 
C 1 382 LYS 382 382 382 LYS LYS C . n 
C 1 383 LEU 383 383 383 LEU LEU C . n 
C 1 384 ASN 384 384 384 ASN ASN C . n 
C 1 385 ARG 385 385 385 ARG ARG C . n 
C 1 386 VAL 386 386 386 VAL VAL C . n 
C 1 387 ILE 387 387 387 ILE ILE C . n 
C 1 388 GLU 388 388 388 GLU GLU C . n 
C 1 389 LYS 389 389 389 LYS LYS C . n 
C 1 390 THR 390 390 390 THR THR C . n 
C 1 391 ASN 391 391 391 ASN ASN C . n 
C 1 392 GLU 392 392 392 GLU GLU C . n 
C 1 393 LYS 393 393 393 LYS LYS C . n 
C 1 394 PHE 394 394 394 PHE PHE C . n 
C 1 395 HIS 395 395 395 HIS HIS C . n 
C 1 396 GLN 396 396 396 GLN GLN C . n 
C 1 397 ILE 397 397 397 ILE ILE C . n 
C 1 398 GLU 398 398 398 GLU GLU C . n 
C 1 399 LYS 399 399 399 LYS LYS C . n 
C 1 400 GLU 400 400 400 GLU GLU C . n 
C 1 401 PHE 401 401 401 PHE PHE C . n 
C 1 402 SER 402 402 402 SER SER C . n 
C 1 403 GLU 403 403 403 GLU GLU C . n 
C 1 404 VAL 404 404 404 VAL VAL C . n 
C 1 405 GLU 405 405 405 GLU GLU C . n 
C 1 406 GLY 406 406 406 GLY GLY C . n 
C 1 407 ARG 407 407 407 ARG ARG C . n 
C 1 408 ILE 408 408 408 ILE ILE C . n 
C 1 409 GLN 409 409 409 GLN GLN C . n 
C 1 410 ASP 410 410 410 ASP ASP C . n 
C 1 411 LEU 411 411 411 LEU LEU C . n 
C 1 412 GLU 412 412 412 GLU GLU C . n 
C 1 413 LYS 413 413 413 LYS LYS C . n 
C 1 414 TYR 414 414 414 TYR TYR C . n 
C 1 415 VAL 415 415 415 VAL VAL C . n 
C 1 416 GLU 416 416 416 GLU GLU C . n 
C 1 417 ASP 417 417 417 ASP ASP C . n 
C 1 418 THR 418 418 418 THR THR C . n 
C 1 419 LYS 419 419 419 LYS LYS C . n 
C 1 420 VAL 420 420 420 VAL VAL C . n 
C 1 421 ASP 421 421 421 ASP ASP C . n 
C 1 422 LEU 422 422 422 LEU LEU C . n 
C 1 423 TRP 423 423 423 TRP TRP C . n 
C 1 424 SER 424 424 424 SER SER C . n 
C 1 425 TYR 425 425 425 TYR TYR C . n 
C 1 426 ASN 426 426 426 ASN ASN C . n 
C 1 427 ALA 427 427 427 ALA ALA C . n 
C 1 428 GLU 428 428 428 GLU GLU C . n 
C 1 429 LEU 429 429 429 LEU LEU C . n 
C 1 430 LEU 430 430 430 LEU LEU C . n 
C 1 431 VAL 431 431 431 VAL VAL C . n 
C 1 432 ALA 432 432 432 ALA ALA C . n 
C 1 433 LEU 433 433 433 LEU LEU C . n 
C 1 434 GLU 434 434 434 GLU GLU C . n 
C 1 435 ASN 435 435 435 ASN ASN C . n 
C 1 436 GLN 436 436 436 GLN GLN C . n 
C 1 437 HIS 437 437 437 HIS HIS C . n 
C 1 438 THR 438 438 438 THR THR C . n 
C 1 439 ILE 439 439 439 ILE ILE C . n 
C 1 440 ASP 440 440 440 ASP ASP C . n 
C 1 441 LEU 441 441 441 LEU LEU C . n 
C 1 442 THR 442 442 442 THR THR C . n 
C 1 443 ASP 443 443 443 ASP ASP C . n 
C 1 444 SER 444 444 444 SER SER C . n 
C 1 445 GLU 445 445 445 GLU GLU C . n 
C 1 446 MET 446 446 446 MET MET C . n 
C 1 447 ASN 447 447 447 ASN ASN C . n 
C 1 448 LYS 448 448 448 LYS LYS C . n 
C 1 449 LEU 449 449 449 LEU LEU C . n 
C 1 450 PHE 450 450 450 PHE PHE C . n 
C 1 451 GLU 451 451 451 GLU GLU C . n 
C 1 452 LYS 452 452 452 LYS LYS C . n 
C 1 453 THR 453 453 453 THR THR C . n 
C 1 454 ARG 454 454 454 ARG ARG C . n 
C 1 455 ARG 455 455 455 ARG ARG C . n 
C 1 456 GLN 456 456 456 GLN GLN C . n 
C 1 457 LEU 457 457 457 LEU LEU C . n 
C 1 458 ARG 458 458 458 ARG ARG C . n 
C 1 459 GLU 459 459 459 GLU GLU C . n 
C 1 460 ASN 460 460 460 ASN ASN C . n 
C 1 461 ALA 461 461 461 ALA ALA C . n 
C 1 462 GLU 462 462 462 GLU GLU C . n 
C 1 463 ASP 463 463 463 ASP ASP C . n 
C 1 464 MET 464 464 464 MET MET C . n 
C 1 465 GLY 465 465 465 GLY GLY C . n 
C 1 466 ASN 466 466 466 ASN ASN C . n 
C 1 467 GLY 467 467 467 GLY GLY C . n 
C 1 468 CYS 468 468 468 CYS CYS C . n 
C 1 469 PHE 469 469 469 PHE PHE C . n 
C 1 470 LYS 470 470 470 LYS LYS C . n 
C 1 471 ILE 471 471 471 ILE ILE C . n 
C 1 472 TYR 472 472 472 TYR TYR C . n 
C 1 473 HIS 473 473 473 HIS HIS C . n 
C 1 474 LYS 474 474 474 LYS LYS C . n 
C 1 475 CYS 475 475 475 CYS CYS C . n 
C 1 476 ASP 476 476 476 ASP ASP C . n 
C 1 477 ASN 477 477 477 ASN ASN C . n 
C 1 478 ALA 478 478 478 ALA ALA C . n 
C 1 479 CYS 479 479 479 CYS CYS C . n 
C 1 480 ILE 480 480 480 ILE ILE C . n 
C 1 481 GLU 481 481 481 GLU GLU C . n 
C 1 482 SER 482 482 482 SER SER C . n 
C 1 483 ILE 483 483 483 ILE ILE C . n 
C 1 484 ARG 484 484 484 ARG ARG C . n 
C 1 485 ASN 485 485 485 ASN ASN C . n 
C 1 486 GLY 486 486 486 GLY GLY C . n 
C 1 487 THR 487 487 487 THR THR C . n 
C 1 488 TYR 488 488 488 TYR TYR C . n 
C 1 489 ASP 489 489 489 ASP ASP C . n 
C 1 490 HIS 490 490 490 HIS HIS C . n 
C 1 491 ASP 491 491 491 ASP ASP C . n 
C 1 492 ILE 492 492 492 ILE ILE C . n 
C 1 493 TYR 493 493 493 TYR TYR C . n 
C 1 494 ARG 494 494 494 ARG ARG C . n 
C 1 495 ASP 495 495 495 ASP ASP C . n 
C 1 496 GLU 496 496 496 GLU GLU C . n 
C 1 497 ALA 497 497 497 ALA ALA C . n 
C 1 498 LEU 498 498 498 LEU LEU C . n 
C 1 499 ASN 499 499 499 ASN ASN C . n 
C 1 500 ASN 500 500 500 ASN ASN C . n 
C 1 501 ARG 501 501 501 ARG ARG C . n 
C 1 502 PHE 502 502 502 PHE PHE C . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
D 2 NAG 1 D NAG 1 A NAG 611 n 
D 2 NAG 2 D NAG 2 A NAG 612 n 
D 2 BMA 3 D BMA 3 A BMA 613 n 
D 2 MAN 4 D MAN 4 A MAN 614 n 
D 2 MAN 5 D MAN 5 A MAN 615 n 
E 3 NAG 1 E NAG 1 A NAG 621 n 
E 3 NAG 2 E NAG 2 A NAG 622 n 
F 2 NAG 1 F NAG 1 B NAG 611 n 
F 2 NAG 2 F NAG 2 B NAG 612 n 
F 2 BMA 3 F BMA 3 B BMA 613 n 
F 2 MAN 4 F MAN 4 B MAN 614 n 
F 2 MAN 5 F MAN 5 B MAN 615 n 
G 3 NAG 1 G NAG 1 B NAG 621 n 
G 3 NAG 2 G NAG 2 B NAG 622 n 
H 2 NAG 1 H NAG 1 C NAG 611 n 
H 2 NAG 2 H NAG 2 C NAG 612 n 
H 2 BMA 3 H BMA 3 C BMA 613 n 
H 2 MAN 4 H MAN 4 C MAN 614 n 
H 2 MAN 5 H MAN 5 C MAN 615 n 
I 3 NAG 1 I NAG 1 C NAG 621 n 
I 3 NAG 2 I NAG 2 C NAG 622 n 
J 4 GAL 1 J GAL 1 E GAL 2   n 
J 4 SIA 2 J SIA 2 E SIA 1   n 
K 4 GAL 1 K GAL 1 D GAL 2   n 
K 4 SIA 2 K SIA 2 D SIA 1   n 
L 4 GAL 1 L GAL 1 F GAL 2   n 
L 4 SIA 2 L SIA 2 F SIA 1   n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 SIA ? ? SIA ? ? 'SUBJECT OF INVESTIGATION' ? 
2 GAL ? ? GAL ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
M 5 NAG 1 601 601 NAG NAG A . 
N 5 NAG 1 601 601 NAG NAG B . 
O 5 NAG 1 601 601 NAG NAG C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B ASP 463 ? OD1 ? B ASP 463 OD1 
2 1 Y 1 B ASP 463 ? OD2 ? B ASP 463 OD2 
3 1 Y 1 C SER 126 ? OG  ? C SER 126 OG  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZW6 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZW6 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZW6 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ZW6 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 12074 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.430 ? 16373 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.919 ? 1778  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 1874  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 2104  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZW6 
_struct.title                        
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus S228 mutant complexed with avian receptor analog LSTa' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZW6 
_struct_keywords.text            'influenza virus, H3N8, hemagglutinin, avain receptor, viral protein' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 2 ? 
G N N 3 ? 
H N N 2 ? 
I N N 3 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 5 ? 
N N N 5 ? 
O N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    8ZW6 
_struct_ref.pdbx_db_accession          8ZW6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZW6 A 1 ? 502 ? 8ZW6 1 ? 502 ? 1 502 
2 1 8ZW6 B 1 ? 502 ? 8ZW6 1 ? 502 ? 1 502 
3 1 8ZW6 C 1 ? 502 ? 8ZW6 1 ? 502 ? 1 502 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 67  ? GLY A 74  ? THR A 67  GLY A 74  1 ? 8  
HELX_P HELX_P2  AA2 ASP A 75  ? GLN A 82  ? ASP A 75  GLN A 82  5 ? 8  
HELX_P HELX_P3  AA3 ASP A 106 ? GLY A 118 ? ASP A 106 GLY A 118 1 ? 13 
HELX_P HELX_P4  AA4 THR A 189 ? TYR A 197 ? THR A 189 TYR A 197 1 ? 9  
HELX_P HELX_P5  AA5 ASP A 368 ? ASN A 380 ? ASP A 368 ASN A 380 1 ? 13 
HELX_P HELX_P6  AA6 LYS A 382 ? VAL A 386 ? LYS A 382 VAL A 386 5 ? 5  
HELX_P HELX_P7  AA7 GLY A 406 ? LEU A 457 ? GLY A 406 LEU A 457 1 ? 52 
HELX_P HELX_P8  AA8 ASP A 476 ? GLY A 486 ? ASP A 476 GLY A 486 1 ? 11 
HELX_P HELX_P9  AA9 TYR A 493 ? PHE A 502 ? TYR A 493 PHE A 502 1 ? 10 
HELX_P HELX_P10 AB1 THR B 67  ? GLY B 74  ? THR B 67  GLY B 74  1 ? 8  
HELX_P HELX_P11 AB2 ASP B 75  ? GLN B 82  ? ASP B 75  GLN B 82  5 ? 8  
HELX_P HELX_P12 AB3 ASP B 106 ? GLY B 118 ? ASP B 106 GLY B 118 1 ? 13 
HELX_P HELX_P13 AB4 THR B 189 ? TYR B 197 ? THR B 189 TYR B 197 1 ? 9  
HELX_P HELX_P14 AB5 LEU B 369 ? ASN B 380 ? LEU B 369 ASN B 380 1 ? 12 
HELX_P HELX_P15 AB6 LYS B 382 ? VAL B 386 ? LYS B 382 VAL B 386 5 ? 5  
HELX_P HELX_P16 AB7 GLY B 406 ? LEU B 457 ? GLY B 406 LEU B 457 1 ? 52 
HELX_P HELX_P17 AB8 ASP B 476 ? GLY B 486 ? ASP B 476 GLY B 486 1 ? 11 
HELX_P HELX_P18 AB9 TYR B 493 ? PHE B 502 ? TYR B 493 PHE B 502 1 ? 10 
HELX_P HELX_P19 AC1 THR C 67  ? GLY C 74  ? THR C 67  GLY C 74  1 ? 8  
HELX_P HELX_P20 AC2 ASP C 75  ? GLN C 82  ? ASP C 75  GLN C 82  5 ? 8  
HELX_P HELX_P21 AC3 ASP C 106 ? GLY C 118 ? ASP C 106 GLY C 118 1 ? 13 
HELX_P HELX_P22 AC4 THR C 189 ? TYR C 197 ? THR C 189 TYR C 197 1 ? 9  
HELX_P HELX_P23 AC5 ASP C 368 ? ASN C 380 ? ASP C 368 ASN C 380 1 ? 13 
HELX_P HELX_P24 AC6 LYS C 382 ? VAL C 386 ? LYS C 382 VAL C 386 5 ? 5  
HELX_P HELX_P25 AC7 GLY C 406 ? LEU C 457 ? GLY C 406 LEU C 457 1 ? 52 
HELX_P HELX_P26 AC8 ASP C 476 ? GLY C 486 ? ASP C 476 GLY C 486 1 ? 11 
HELX_P HELX_P27 AC9 ASP C 489 ? PHE C 502 ? ASP C 489 PHE C 502 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 16  SG  ? ? ? 1_555 A CYS 468 SG ? ? A CYS 16  A CYS 468 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf2  disulf ?    ? A CYS 54  SG  ? ? ? 1_555 A CYS 279 SG ? ? A CYS 54  A CYS 279 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf3  disulf ?    ? A CYS 66  SG  ? ? ? 1_555 A CYS 78  SG ? ? A CYS 66  A CYS 78  1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf4  disulf ?    ? A CYS 99  SG  ? ? ? 1_555 A CYS 141 SG ? ? A CYS 99  A CYS 141 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf5  disulf ?    ? A CYS 283 SG  ? ? ? 1_555 A CYS 307 SG ? ? A CYS 283 A CYS 307 1_555 ? ? ? ? ? ? ? 2.028 ? ?               
disulf6  disulf ?    ? A CYS 475 SG  ? ? ? 1_555 A CYS 479 SG ? ? A CYS 475 A CYS 479 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf7  disulf ?    ? B CYS 16  SG  ? ? ? 1_555 B CYS 468 SG ? ? B CYS 16  B CYS 468 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf8  disulf ?    ? B CYS 54  SG  ? ? ? 1_555 B CYS 279 SG ? ? B CYS 54  B CYS 279 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf9  disulf ?    ? B CYS 66  SG  ? ? ? 1_555 B CYS 78  SG ? ? B CYS 66  B CYS 78  1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf10 disulf ?    ? B CYS 99  SG  ? ? ? 1_555 B CYS 141 SG ? ? B CYS 99  B CYS 141 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf11 disulf ?    ? B CYS 283 SG  ? ? ? 1_555 B CYS 307 SG ? ? B CYS 283 B CYS 307 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf12 disulf ?    ? B CYS 475 SG  ? ? ? 1_555 B CYS 479 SG ? ? B CYS 475 B CYS 479 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf13 disulf ?    ? C CYS 16  SG  ? ? ? 1_555 C CYS 468 SG ? ? C CYS 16  C CYS 468 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf14 disulf ?    ? C CYS 54  SG  ? ? ? 1_555 C CYS 279 SG ? ? C CYS 54  C CYS 279 1_555 ? ? ? ? ? ? ? 2.027 ? ?               
disulf15 disulf ?    ? C CYS 66  SG  ? ? ? 1_555 C CYS 78  SG ? ? C CYS 66  C CYS 78  1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf16 disulf ?    ? C CYS 99  SG  ? ? ? 1_555 C CYS 141 SG ? ? C CYS 99  C CYS 141 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf17 disulf ?    ? C CYS 283 SG  ? ? ? 1_555 C CYS 307 SG ? ? C CYS 283 C CYS 307 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf18 disulf ?    ? C CYS 475 SG  ? ? ? 1_555 C CYS 479 SG ? ? C CYS 475 C CYS 479 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
covale1  covale one  ? A ASN 40  ND2 ? ? ? 1_555 M NAG .   C1 ? ? A ASN 40  A NAG 601 1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale2  covale one  ? A ASN 167 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 167 D NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale3  covale one  ? A ASN 287 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 287 E NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale4  covale one  ? B ASN 40  ND2 ? ? ? 1_555 N NAG .   C1 ? ? B ASN 40  B NAG 601 1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale5  covale one  ? B ASN 167 ND2 ? ? ? 1_555 F NAG .   C1 ? ? B ASN 167 F NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale6  covale one  ? B ASN 287 ND2 ? ? ? 1_555 G NAG .   C1 ? ? B ASN 287 G NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale7  covale one  ? C ASN 40  ND2 ? ? ? 1_555 O NAG .   C1 ? ? C ASN 40  C NAG 601 1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale8  covale one  ? C ASN 167 ND2 ? ? ? 1_555 H NAG .   C1 ? ? C ASN 167 H NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale9  covale one  ? C ASN 287 ND2 ? ? ? 1_555 I NAG .   C1 ? ? C ASN 287 I NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale10 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale11 covale both ? D NAG .   O4  ? ? ? 1_555 D BMA .   C1 ? ? D NAG 2   D BMA 3   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale12 covale both ? D BMA .   O3  ? ? ? 1_555 D MAN .   C1 ? ? D BMA 3   D MAN 4   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale13 covale both ? D BMA .   O6  ? ? ? 1_555 D MAN .   C1 ? ? D BMA 3   D MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale14 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? E NAG 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale15 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale16 covale both ? F NAG .   O4  ? ? ? 1_555 F BMA .   C1 ? ? F NAG 2   F BMA 3   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale17 covale both ? F BMA .   O3  ? ? ? 1_555 F MAN .   C1 ? ? F BMA 3   F MAN 4   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale18 covale both ? F BMA .   O6  ? ? ? 1_555 F MAN .   C1 ? ? F BMA 3   F MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale19 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale20 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale21 covale both ? H NAG .   O4  ? ? ? 1_555 H BMA .   C1 ? ? H NAG 2   H BMA 3   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale22 covale both ? H BMA .   O3  ? ? ? 1_555 H MAN .   C1 ? ? H BMA 3   H MAN 4   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale23 covale both ? H BMA .   O6  ? ? ? 1_555 H MAN .   C1 ? ? H BMA 3   H MAN 5   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale24 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? I NAG 1   I NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale25 covale both ? J GAL .   O3  ? ? ? 1_555 J SIA .   C2 ? ? J GAL 1   J SIA 2   1_555 ? ? ? ? ? ? ? 1.373 ? ?               
covale26 covale both ? K GAL .   O3  ? ? ? 1_555 K SIA .   C2 ? ? K GAL 1   K SIA 2   1_555 ? ? ? ? ? ? ? 1.373 ? ?               
covale27 covale both ? L GAL .   O3  ? ? ? 1_555 L SIA .   C2 ? ? L GAL 1   L SIA 2   1_555 ? ? ? ? ? ? ? 1.373 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG D .   ? ASN A 167 ? NAG D 1   ? 1_555 ASN A 167 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG E .   ? ASN A 287 ? NAG E 1   ? 1_555 ASN A 287 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG F .   ? ASN B 167 ? NAG F 1   ? 1_555 ASN B 167 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG G .   ? ASN B 287 ? NAG G 1   ? 1_555 ASN B 287 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG H .   ? ASN C 167 ? NAG H 1   ? 1_555 ASN C 167 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG I .   ? ASN C 287 ? NAG I 1   ? 1_555 ASN C 287 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG M .   ? ASN A 40  ? NAG A 601 ? 1_555 ASN A 40  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG N .   ? ASN B 40  ? NAG B 601 ? 1_555 ASN B 40  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  NAG O .   ? ASN C 40  ? NAG C 601 ? 1_555 ASN C 40  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
10 CYS A 16  ? CYS A 468 ? CYS A 16  ? 1_555 CYS A 468 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS A 54  ? CYS A 279 ? CYS A 54  ? 1_555 CYS A 279 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS A 66  ? CYS A 78  ? CYS A 66  ? 1_555 CYS A 78  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS A 99  ? CYS A 141 ? CYS A 99  ? 1_555 CYS A 141 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
14 CYS A 283 ? CYS A 307 ? CYS A 283 ? 1_555 CYS A 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
15 CYS A 475 ? CYS A 479 ? CYS A 475 ? 1_555 CYS A 479 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
16 CYS B 16  ? CYS B 468 ? CYS B 16  ? 1_555 CYS B 468 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS B 54  ? CYS B 279 ? CYS B 54  ? 1_555 CYS B 279 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS B 66  ? CYS B 78  ? CYS B 66  ? 1_555 CYS B 78  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
19 CYS B 99  ? CYS B 141 ? CYS B 99  ? 1_555 CYS B 141 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS B 283 ? CYS B 307 ? CYS B 283 ? 1_555 CYS B 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
21 CYS B 475 ? CYS B 479 ? CYS B 475 ? 1_555 CYS B 479 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
22 CYS C 16  ? CYS C 468 ? CYS C 16  ? 1_555 CYS C 468 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
23 CYS C 54  ? CYS C 279 ? CYS C 54  ? 1_555 CYS C 279 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
24 CYS C 66  ? CYS C 78  ? CYS C 66  ? 1_555 CYS C 78  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
25 CYS C 99  ? CYS C 141 ? CYS C 99  ? 1_555 CYS C 141 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
26 CYS C 283 ? CYS C 307 ? CYS C 283 ? 1_555 CYS C 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
27 CYS C 475 ? CYS C 479 ? CYS C 475 ? 1_555 CYS C 479 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASN 56 A . ? ASN 56 A PRO 57 A ? PRO 57 A 1 -0.92 
2 ASN 56 B . ? ASN 56 B PRO 57 B ? PRO 57 B 1 -1.34 
3 ASN 56 C . ? ASN 56 C PRO 57 C ? PRO 57 C 1 -1.14 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
AA7 ? 5 ? 
AA8 ? 4 ? 
AA9 ? 2 ? 
AB1 ? 2 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 5 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 3 ? 
AB8 ? 2 ? 
AB9 ? 3 ? 
AC1 ? 5 ? 
AC2 ? 4 ? 
AC3 ? 2 ? 
AC4 ? 2 ? 
AC5 ? 4 ? 
AC6 ? 4 ? 
AC7 ? 5 ? 
AC8 ? 2 ? 
AC9 ? 2 ? 
AD1 ? 3 ? 
AD2 ? 2 ? 
AD3 ? 3 ? 
AD4 ? 5 ? 
AD5 ? 4 ? 
AD6 ? 2 ? 
AD7 ? 2 ? 
AD8 ? 4 ? 
AD9 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA5 1 2 ? parallel      
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? parallel      
AB8 1 2 ? parallel      
AB9 1 2 ? parallel      
AB9 2 3 ? parallel      
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC1 4 5 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC7 4 5 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AD1 1 2 ? parallel      
AD1 2 3 ? parallel      
AD2 1 2 ? parallel      
AD3 1 2 ? parallel      
AD3 2 3 ? parallel      
AD4 1 2 ? anti-parallel 
AD4 2 3 ? anti-parallel 
AD4 3 4 ? anti-parallel 
AD4 4 5 ? anti-parallel 
AD5 1 2 ? anti-parallel 
AD5 2 3 ? anti-parallel 
AD5 3 4 ? anti-parallel 
AD6 1 2 ? anti-parallel 
AD7 1 2 ? anti-parallel 
AD8 1 2 ? anti-parallel 
AD8 2 3 ? anti-parallel 
AD8 3 4 ? anti-parallel 
AD9 1 2 ? anti-parallel 
AD9 2 3 ? anti-parallel 
AD9 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 364 ? GLN A 365 ? GLY A 364 GLN A 365 
AA1 2 TYR A 353 ? GLN A 358 ? TYR A 353 GLN A 358 
AA1 3 ALA A 13  ? HIS A 19  ? ALA A 13  HIS A 19  
AA1 4 CYS A 468 ? ILE A 471 ? CYS A 468 ILE A 471 
AA1 5 ALA A 461 ? ASP A 463 ? ALA A 461 ASP A 463 
AA2 1 THR A 26  ? VAL A 28  ? THR A 26  VAL A 28  
AA2 2 ILE A 36  ? VAL A 38  ? ILE A 36  VAL A 38  
AA3 1 ALA A 41  ? GLU A 43  ? ALA A 41  GLU A 43  
AA3 2 LYS A 317 ? ALA A 319 ? LYS A 317 ALA A 319 
AA4 1 VAL A 45  ? GLN A 46  ? VAL A 45  GLN A 46  
AA4 2 PHE A 296 ? GLN A 297 ? PHE A 296 GLN A 297 
AA4 3 LYS A 309 ? TYR A 310 ? LYS A 309 TYR A 310 
AA5 1 ILE A 53  ? ASN A 56  ? ILE A 53  ASN A 56  
AA5 2 ILE A 276 ? ILE A 280 ? ILE A 276 ILE A 280 
AA6 1 VAL A 60  ? GLY A 63  ? VAL A 60  GLY A 63  
AA6 2 LEU A 88  ? GLU A 91  ? LEU A 88  GLU A 91  
AA6 3 SER A 268 ? ARG A 271 ? SER A 268 ARG A 271 
AA7 1 PHE A 122 ? THR A 124 ? PHE A 122 THR A 124 
AA7 2 GLY A 258 ? LYS A 261 ? GLY A 258 LYS A 261 
AA7 3 LYS A 178 ? HIS A 186 ? LYS A 178 HIS A 186 
AA7 4 LEU A 253 ? PRO A 256 ? LEU A 253 PRO A 256 
AA7 5 LEU A 153 ? TRP A 155 ? LEU A 153 TRP A 155 
AA8 1 PHE A 122 ? THR A 124 ? PHE A 122 THR A 124 
AA8 2 GLY A 258 ? LYS A 261 ? GLY A 258 LYS A 261 
AA8 3 LYS A 178 ? HIS A 186 ? LYS A 178 HIS A 186 
AA8 4 ARG A 231 ? VAL A 239 ? ARG A 231 VAL A 239 
AA9 1 VAL A 132 ? SER A 133 ? VAL A 132 SER A 133 
AA9 2 THR A 157 ? LYS A 158 ? THR A 157 LYS A 158 
AB1 1 SER A 138 ? ARG A 143 ? SER A 138 ARG A 143 
AB1 2 ALA A 146 ? GLY A 148 ? ALA A 146 GLY A 148 
AB2 1 LEU A 166 ? PRO A 171 ? LEU A 166 PRO A 171 
AB2 2 VAL A 244 ? SER A 249 ? VAL A 244 SER A 249 
AB2 3 VAL A 204 ? SER A 207 ? VAL A 204 SER A 207 
AB2 4 GLN A 212 ? ILE A 215 ? GLN A 212 ILE A 215 
AB3 1 GLY A 288 ? SER A 289 ? GLY A 288 SER A 289 
AB3 2 CYS A 283 ? THR A 285 ? CYS A 283 THR A 285 
AB3 3 TYR A 304 ? CYS A 307 ? TYR A 304 CYS A 307 
AB3 4 ASN A 391 ? LYS A 393 ? ASN A 391 LYS A 393 
AB4 1 THR B 363 ? ASP B 368 ? THR B 363 ASP B 368 
AB4 2 TYR B 353 ? GLN B 358 ? TYR B 353 GLN B 358 
AB4 3 ALA B 13  ? HIS B 19  ? ALA B 13  HIS B 19  
AB4 4 CYS B 468 ? ILE B 471 ? CYS B 468 ILE B 471 
AB4 5 ALA B 461 ? ASP B 463 ? ALA B 461 ASP B 463 
AB5 1 THR B 26  ? VAL B 28  ? THR B 26  VAL B 28  
AB5 2 ILE B 36  ? VAL B 38  ? ILE B 36  VAL B 38  
AB6 1 ALA B 41  ? GLU B 43  ? ALA B 41  GLU B 43  
AB6 2 LYS B 317 ? ALA B 319 ? LYS B 317 ALA B 319 
AB7 1 VAL B 45  ? GLN B 46  ? VAL B 45  GLN B 46  
AB7 2 PHE B 296 ? GLN B 297 ? PHE B 296 GLN B 297 
AB7 3 LYS B 309 ? TYR B 310 ? LYS B 309 TYR B 310 
AB8 1 ILE B 53  ? ASN B 56  ? ILE B 53  ASN B 56  
AB8 2 ILE B 276 ? ILE B 280 ? ILE B 276 ILE B 280 
AB9 1 VAL B 60  ? ASP B 62  ? VAL B 60  ASP B 62  
AB9 2 LEU B 88  ? GLU B 91  ? LEU B 88  GLU B 91  
AB9 3 SER B 268 ? ARG B 271 ? SER B 268 ARG B 271 
AC1 1 PHE B 122 ? THR B 124 ? PHE B 122 THR B 124 
AC1 2 GLY B 258 ? LYS B 261 ? GLY B 258 LYS B 261 
AC1 3 LYS B 178 ? HIS B 186 ? LYS B 178 HIS B 186 
AC1 4 LEU B 253 ? PRO B 256 ? LEU B 253 PRO B 256 
AC1 5 LEU B 153 ? TRP B 155 ? LEU B 153 TRP B 155 
AC2 1 PHE B 122 ? THR B 124 ? PHE B 122 THR B 124 
AC2 2 GLY B 258 ? LYS B 261 ? GLY B 258 LYS B 261 
AC2 3 LYS B 178 ? HIS B 186 ? LYS B 178 HIS B 186 
AC2 4 ARG B 231 ? VAL B 239 ? ARG B 231 VAL B 239 
AC3 1 VAL B 132 ? SER B 133 ? VAL B 132 SER B 133 
AC3 2 THR B 157 ? LYS B 158 ? THR B 157 LYS B 158 
AC4 1 SER B 138 ? ARG B 143 ? SER B 138 ARG B 143 
AC4 2 ALA B 146 ? GLY B 148 ? ALA B 146 GLY B 148 
AC5 1 LEU B 166 ? PRO B 171 ? LEU B 166 PRO B 171 
AC5 2 VAL B 244 ? SER B 249 ? VAL B 244 SER B 249 
AC5 3 VAL B 204 ? SER B 207 ? VAL B 204 SER B 207 
AC5 4 GLN B 212 ? ILE B 215 ? GLN B 212 ILE B 215 
AC6 1 GLY B 288 ? SER B 289 ? GLY B 288 SER B 289 
AC6 2 CYS B 283 ? THR B 285 ? CYS B 283 THR B 285 
AC6 3 TYR B 304 ? CYS B 307 ? TYR B 304 CYS B 307 
AC6 4 ASN B 391 ? LYS B 393 ? ASN B 391 LYS B 393 
AC7 1 GLY C 364 ? GLN C 365 ? GLY C 364 GLN C 365 
AC7 2 TYR C 353 ? GLN C 358 ? TYR C 353 GLN C 358 
AC7 3 ALA C 13  ? HIS C 19  ? ALA C 13  HIS C 19  
AC7 4 CYS C 468 ? ILE C 471 ? CYS C 468 ILE C 471 
AC7 5 ALA C 461 ? ASP C 463 ? ALA C 461 ASP C 463 
AC8 1 THR C 26  ? VAL C 28  ? THR C 26  VAL C 28  
AC8 2 ILE C 36  ? VAL C 38  ? ILE C 36  VAL C 38  
AC9 1 ALA C 41  ? GLU C 43  ? ALA C 41  GLU C 43  
AC9 2 LYS C 317 ? ALA C 319 ? LYS C 317 ALA C 319 
AD1 1 VAL C 45  ? GLN C 46  ? VAL C 45  GLN C 46  
AD1 2 PHE C 296 ? GLN C 297 ? PHE C 296 GLN C 297 
AD1 3 LYS C 309 ? TYR C 310 ? LYS C 309 TYR C 310 
AD2 1 ILE C 53  ? ASN C 56  ? ILE C 53  ASN C 56  
AD2 2 ILE C 276 ? ILE C 280 ? ILE C 276 ILE C 280 
AD3 1 VAL C 60  ? ASP C 62  ? VAL C 60  ASP C 62  
AD3 2 LEU C 88  ? GLU C 91  ? LEU C 88  GLU C 91  
AD3 3 SER C 268 ? ARG C 271 ? SER C 268 ARG C 271 
AD4 1 PHE C 122 ? THR C 124 ? PHE C 122 THR C 124 
AD4 2 GLY C 258 ? LYS C 261 ? GLY C 258 LYS C 261 
AD4 3 LYS C 178 ? HIS C 186 ? LYS C 178 HIS C 186 
AD4 4 LEU C 253 ? PRO C 256 ? LEU C 253 PRO C 256 
AD4 5 LEU C 153 ? TRP C 155 ? LEU C 153 TRP C 155 
AD5 1 PHE C 122 ? THR C 124 ? PHE C 122 THR C 124 
AD5 2 GLY C 258 ? LYS C 261 ? GLY C 258 LYS C 261 
AD5 3 LYS C 178 ? HIS C 186 ? LYS C 178 HIS C 186 
AD5 4 ARG C 231 ? VAL C 239 ? ARG C 231 VAL C 239 
AD6 1 VAL C 132 ? SER C 133 ? VAL C 132 SER C 133 
AD6 2 THR C 157 ? LYS C 158 ? THR C 157 LYS C 158 
AD7 1 SER C 138 ? ARG C 143 ? SER C 138 ARG C 143 
AD7 2 ALA C 146 ? GLY C 148 ? ALA C 146 GLY C 148 
AD8 1 LEU C 166 ? PRO C 171 ? LEU C 166 PRO C 171 
AD8 2 VAL C 244 ? SER C 249 ? VAL C 244 SER C 249 
AD8 3 VAL C 204 ? SER C 207 ? VAL C 204 SER C 207 
AD8 4 GLN C 212 ? ILE C 215 ? GLN C 212 ILE C 215 
AD9 1 GLY C 288 ? SER C 289 ? GLY C 288 SER C 289 
AD9 2 CYS C 283 ? THR C 285 ? CYS C 283 THR C 285 
AD9 3 TYR C 304 ? CYS C 307 ? TYR C 304 CYS C 307 
AD9 4 ASN C 391 ? LYS C 393 ? ASN C 391 LYS C 393 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLY A 364 ? O GLY A 364 N HIS A 357 ? N HIS A 357 
AA1 2 3 O ARG A 356 ? O ARG A 356 N CYS A 16  ? N CYS A 16  
AA1 3 4 N LEU A 15  ? N LEU A 15  O PHE A 469 ? O PHE A 469 
AA1 4 5 O LYS A 470 ? O LYS A 470 N GLU A 462 ? N GLU A 462 
AA2 1 2 N THR A 26  ? N THR A 26  O VAL A 38  ? O VAL A 38  
AA3 1 2 N THR A 42  ? N THR A 42  O LEU A 318 ? O LEU A 318 
AA4 1 2 N GLN A 46  ? N GLN A 46  O PHE A 296 ? O PHE A 296 
AA4 2 3 N GLN A 297 ? N GLN A 297 O LYS A 309 ? O LYS A 309 
AA5 1 2 N ILE A 53  ? N ILE A 53  O GLU A 277 ? O GLU A 277 
AA6 1 2 N LEU A 61  ? N LEU A 61  O LEU A 88  ? O LEU A 88  
AA6 2 3 N PHE A 89  ? N PHE A 89  O MET A 270 ? O MET A 270 
AA7 1 2 N ILE A 123 ? N ILE A 123 O PHE A 259 ? O PHE A 259 
AA7 2 3 O PHE A 260 ? O PHE A 260 N LEU A 179 ? N LEU A 179 
AA7 3 4 N GLY A 183 ? N GLY A 183 O ILE A 254 ? O ILE A 254 
AA7 4 5 O ALA A 255 ? O ALA A 255 N ASN A 154 ? N ASN A 154 
AA8 1 2 N ILE A 123 ? N ILE A 123 O PHE A 259 ? O PHE A 259 
AA8 2 3 O PHE A 260 ? O PHE A 260 N LEU A 179 ? N LEU A 179 
AA8 3 4 N TYR A 180 ? N TYR A 180 O THR A 237 ? O THR A 237 
AA9 1 2 N SER A 133 ? N SER A 133 O THR A 157 ? O THR A 157 
AB1 1 2 N CYS A 141 ? N CYS A 141 O GLY A 148 ? O GLY A 148 
AB2 1 2 N LEU A 166 ? N LEU A 166 O SER A 249 ? O SER A 249 
AB2 2 3 O ASN A 248 ? O ASN A 248 N THR A 205 ? N THR A 205 
AB2 3 4 N VAL A 206 ? N VAL A 206 O GLN A 213 ? O GLN A 213 
AB3 1 2 O GLY A 288 ? O GLY A 288 N THR A 285 ? N THR A 285 
AB3 2 3 N ILE A 284 ? N ILE A 284 O TYR A 304 ? O TYR A 304 
AB3 3 4 N GLY A 305 ? N GLY A 305 O LYS A 393 ? O LYS A 393 
AB4 1 2 O ASP B 368 ? O ASP B 368 N TYR B 353 ? N TYR B 353 
AB4 2 3 O ARG B 356 ? O ARG B 356 N CYS B 16  ? N CYS B 16  
AB4 3 4 N LEU B 15  ? N LEU B 15  O PHE B 469 ? O PHE B 469 
AB4 4 5 O LYS B 470 ? O LYS B 470 N GLU B 462 ? N GLU B 462 
AB5 1 2 N THR B 26  ? N THR B 26  O VAL B 38  ? O VAL B 38  
AB6 1 2 N THR B 42  ? N THR B 42  O LEU B 318 ? O LEU B 318 
AB7 1 2 N GLN B 46  ? N GLN B 46  O PHE B 296 ? O PHE B 296 
AB7 2 3 N GLN B 297 ? N GLN B 297 O LYS B 309 ? O LYS B 309 
AB8 1 2 N ILE B 53  ? N ILE B 53  O GLU B 277 ? O GLU B 277 
AB9 1 2 N LEU B 61  ? N LEU B 61  O LEU B 88  ? O LEU B 88  
AB9 2 3 N PHE B 89  ? N PHE B 89  O MET B 270 ? O MET B 270 
AC1 1 2 N ILE B 123 ? N ILE B 123 O PHE B 259 ? O PHE B 259 
AC1 2 3 O PHE B 260 ? O PHE B 260 N LEU B 179 ? N LEU B 179 
AC1 3 4 N GLY B 183 ? N GLY B 183 O ILE B 254 ? O ILE B 254 
AC1 4 5 O ALA B 255 ? O ALA B 255 N ASN B 154 ? N ASN B 154 
AC2 1 2 N ILE B 123 ? N ILE B 123 O PHE B 259 ? O PHE B 259 
AC2 2 3 O PHE B 260 ? O PHE B 260 N LEU B 179 ? N LEU B 179 
AC2 3 4 N TYR B 180 ? N TYR B 180 O THR B 237 ? O THR B 237 
AC3 1 2 N SER B 133 ? N SER B 133 O THR B 157 ? O THR B 157 
AC4 1 2 N CYS B 141 ? N CYS B 141 O GLY B 148 ? O GLY B 148 
AC5 1 2 N LEU B 166 ? N LEU B 166 O SER B 249 ? O SER B 249 
AC5 2 3 O ASN B 248 ? O ASN B 248 N THR B 205 ? N THR B 205 
AC5 3 4 N VAL B 206 ? N VAL B 206 O GLN B 213 ? O GLN B 213 
AC6 1 2 O GLY B 288 ? O GLY B 288 N THR B 285 ? N THR B 285 
AC6 2 3 N ILE B 284 ? N ILE B 284 O TYR B 304 ? O TYR B 304 
AC6 3 4 N GLY B 305 ? N GLY B 305 O LYS B 393 ? O LYS B 393 
AC7 1 2 O GLY C 364 ? O GLY C 364 N HIS C 357 ? N HIS C 357 
AC7 2 3 O ARG C 356 ? O ARG C 356 N CYS C 16  ? N CYS C 16  
AC7 3 4 N LEU C 15  ? N LEU C 15  O PHE C 469 ? O PHE C 469 
AC7 4 5 O LYS C 470 ? O LYS C 470 N GLU C 462 ? N GLU C 462 
AC8 1 2 N THR C 26  ? N THR C 26  O VAL C 38  ? O VAL C 38  
AC9 1 2 N THR C 42  ? N THR C 42  O LEU C 318 ? O LEU C 318 
AD1 1 2 N GLN C 46  ? N GLN C 46  O PHE C 296 ? O PHE C 296 
AD1 2 3 N GLN C 297 ? N GLN C 297 O LYS C 309 ? O LYS C 309 
AD2 1 2 N ILE C 53  ? N ILE C 53  O GLU C 277 ? O GLU C 277 
AD3 1 2 N LEU C 61  ? N LEU C 61  O VAL C 90  ? O VAL C 90  
AD3 2 3 N PHE C 89  ? N PHE C 89  O MET C 270 ? O MET C 270 
AD4 1 2 N ILE C 123 ? N ILE C 123 O PHE C 259 ? O PHE C 259 
AD4 2 3 O PHE C 260 ? O PHE C 260 N LEU C 179 ? N LEU C 179 
AD4 3 4 N GLY C 183 ? N GLY C 183 O ILE C 254 ? O ILE C 254 
AD4 4 5 O ALA C 255 ? O ALA C 255 N ASN C 154 ? N ASN C 154 
AD5 1 2 N ILE C 123 ? N ILE C 123 O PHE C 259 ? O PHE C 259 
AD5 2 3 O PHE C 260 ? O PHE C 260 N LEU C 179 ? N LEU C 179 
AD5 3 4 N TYR C 180 ? N TYR C 180 O THR C 237 ? O THR C 237 
AD6 1 2 N SER C 133 ? N SER C 133 O THR C 157 ? O THR C 157 
AD7 1 2 N CYS C 141 ? N CYS C 141 O GLY C 148 ? O GLY C 148 
AD8 1 2 N LEU C 166 ? N LEU C 166 O SER C 249 ? O SER C 249 
AD8 2 3 O ASN C 248 ? O ASN C 248 N THR C 205 ? N THR C 205 
AD8 3 4 N VAL C 206 ? N VAL C 206 O GLN C 213 ? O GLN C 213 
AD9 1 2 O GLY C 288 ? O GLY C 288 N THR C 285 ? N THR C 285 
AD9 2 3 N ILE C 284 ? N ILE C 284 O TYR C 304 ? O TYR C 304 
AD9 3 4 N GLY C 305 ? N GLY C 305 O LYS C 393 ? O LYS C 393 
# 
_pdbx_entry_details.entry_id                   8ZW6 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OE2 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   GLU 
_pdbx_validate_close_contact.auth_seq_id_1    192 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O9 
_pdbx_validate_close_contact.auth_asym_id_2   K 
_pdbx_validate_close_contact.auth_comp_id_2   SIA 
_pdbx_validate_close_contact.auth_seq_id_2    2 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ARG B 64  ? ? 57.76   -113.17 
2 1 ASN B 135 ? ? 60.28   61.36   
3 1 ARG C 64  ? ? 58.26   -115.94 
4 1 VAL C 386 ? ? -123.06 -56.03  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZW6 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8ZW6 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.75 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               250384 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'HN/4-10 H3N8 S228 HA complexed with LSTa' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8ZW6 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8ZW6 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZW6 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A LEU 1   ? A LEU 1   
2  1 Y 1 A GLN 2   ? A GLN 2   
3  1 Y 1 A GLN 3   ? A GLN 3   
4  1 Y 1 A ASN 4   ? A ASN 4   
5  1 Y 1 A LEU 5   ? A LEU 5   
6  1 Y 1 A PRO 6   ? A PRO 6   
7  1 Y 1 A GLY 7   ? A GLY 7   
8  1 Y 1 A LYS 8   ? A LYS 8   
9  1 Y 1 A ASP 9   ? A ASP 9   
10 1 Y 1 A SER 10  ? A SER 10  
11 1 Y 1 A SER 11  ? A SER 11  
12 1 Y 1 A TYR 100 ? A TYR 100 
13 1 Y 1 A LYS 328 ? A LYS 328 
14 1 Y 1 A GLN 329 ? A GLN 329 
15 1 Y 1 A THR 330 ? A THR 330 
16 1 Y 1 A ARG 331 ? A ARG 331 
17 1 Y 1 A GLY 332 ? A GLY 332 
18 1 Y 1 A LEU 333 ? A LEU 333 
19 1 Y 1 A PHE 334 ? A PHE 334 
20 1 Y 1 A GLY 335 ? A GLY 335 
21 1 Y 1 A ALA 336 ? A ALA 336 
22 1 Y 1 B LEU 1   ? B LEU 1   
23 1 Y 1 B GLN 2   ? B GLN 2   
24 1 Y 1 B GLN 3   ? B GLN 3   
25 1 Y 1 B ASN 4   ? B ASN 4   
26 1 Y 1 B LEU 5   ? B LEU 5   
27 1 Y 1 B PRO 6   ? B PRO 6   
28 1 Y 1 B GLY 7   ? B GLY 7   
29 1 Y 1 B LYS 8   ? B LYS 8   
30 1 Y 1 B ASP 9   ? B ASP 9   
31 1 Y 1 B SER 10  ? B SER 10  
32 1 Y 1 B SER 11  ? B SER 11  
33 1 Y 1 B GLN 329 ? B GLN 329 
34 1 Y 1 B THR 330 ? B THR 330 
35 1 Y 1 B ARG 331 ? B ARG 331 
36 1 Y 1 B GLY 332 ? B GLY 332 
37 1 Y 1 B LEU 333 ? B LEU 333 
38 1 Y 1 B PHE 334 ? B PHE 334 
39 1 Y 1 B GLY 335 ? B GLY 335 
40 1 Y 1 C LEU 1   ? C LEU 1   
41 1 Y 1 C GLN 2   ? C GLN 2   
42 1 Y 1 C GLN 3   ? C GLN 3   
43 1 Y 1 C ASN 4   ? C ASN 4   
44 1 Y 1 C LEU 5   ? C LEU 5   
45 1 Y 1 C PRO 6   ? C PRO 6   
46 1 Y 1 C GLY 7   ? C GLY 7   
47 1 Y 1 C LYS 8   ? C LYS 8   
48 1 Y 1 C ASP 9   ? C ASP 9   
49 1 Y 1 C SER 10  ? C SER 10  
50 1 Y 1 C SER 11  ? C SER 11  
51 1 Y 1 C LYS 328 ? C LYS 328 
52 1 Y 1 C GLN 329 ? C GLN 329 
53 1 Y 1 C THR 330 ? C THR 330 
54 1 Y 1 C ARG 331 ? C ARG 331 
55 1 Y 1 C GLY 332 ? C GLY 332 
56 1 Y 1 C LEU 333 ? C LEU 333 
57 1 Y 1 C PHE 334 ? C PHE 334 
58 1 Y 1 C GLY 335 ? C GLY 335 
59 1 Y 1 C ALA 336 ? C ALA 336 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GAL C1   C N R 112 
GAL C2   C N R 113 
GAL C3   C N S 114 
GAL C4   C N R 115 
GAL C5   C N R 116 
GAL C6   C N N 117 
GAL O1   O N N 118 
GAL O2   O N N 119 
GAL O3   O N N 120 
GAL O4   O N N 121 
GAL O5   O N N 122 
GAL O6   O N N 123 
GAL H1   H N N 124 
GAL H2   H N N 125 
GAL H3   H N N 126 
GAL H4   H N N 127 
GAL H5   H N N 128 
GAL H61  H N N 129 
GAL H62  H N N 130 
GAL HO1  H N N 131 
GAL HO2  H N N 132 
GAL HO3  H N N 133 
GAL HO4  H N N 134 
GAL HO6  H N N 135 
GLN N    N N N 136 
GLN CA   C N S 137 
GLN C    C N N 138 
GLN O    O N N 139 
GLN CB   C N N 140 
GLN CG   C N N 141 
GLN CD   C N N 142 
GLN OE1  O N N 143 
GLN NE2  N N N 144 
GLN OXT  O N N 145 
GLN H    H N N 146 
GLN H2   H N N 147 
GLN HA   H N N 148 
GLN HB2  H N N 149 
GLN HB3  H N N 150 
GLN HG2  H N N 151 
GLN HG3  H N N 152 
GLN HE21 H N N 153 
GLN HE22 H N N 154 
GLN HXT  H N N 155 
GLU N    N N N 156 
GLU CA   C N S 157 
GLU C    C N N 158 
GLU O    O N N 159 
GLU CB   C N N 160 
GLU CG   C N N 161 
GLU CD   C N N 162 
GLU OE1  O N N 163 
GLU OE2  O N N 164 
GLU OXT  O N N 165 
GLU H    H N N 166 
GLU H2   H N N 167 
GLU HA   H N N 168 
GLU HB2  H N N 169 
GLU HB3  H N N 170 
GLU HG2  H N N 171 
GLU HG3  H N N 172 
GLU HE2  H N N 173 
GLU HXT  H N N 174 
GLY N    N N N 175 
GLY CA   C N N 176 
GLY C    C N N 177 
GLY O    O N N 178 
GLY OXT  O N N 179 
GLY H    H N N 180 
GLY H2   H N N 181 
GLY HA2  H N N 182 
GLY HA3  H N N 183 
GLY HXT  H N N 184 
HIS N    N N N 185 
HIS CA   C N S 186 
HIS C    C N N 187 
HIS O    O N N 188 
HIS CB   C N N 189 
HIS CG   C Y N 190 
HIS ND1  N Y N 191 
HIS CD2  C Y N 192 
HIS CE1  C Y N 193 
HIS NE2  N Y N 194 
HIS OXT  O N N 195 
HIS H    H N N 196 
HIS H2   H N N 197 
HIS HA   H N N 198 
HIS HB2  H N N 199 
HIS HB3  H N N 200 
HIS HD1  H N N 201 
HIS HD2  H N N 202 
HIS HE1  H N N 203 
HIS HE2  H N N 204 
HIS HXT  H N N 205 
ILE N    N N N 206 
ILE CA   C N S 207 
ILE C    C N N 208 
ILE O    O N N 209 
ILE CB   C N S 210 
ILE CG1  C N N 211 
ILE CG2  C N N 212 
ILE CD1  C N N 213 
ILE OXT  O N N 214 
ILE H    H N N 215 
ILE H2   H N N 216 
ILE HA   H N N 217 
ILE HB   H N N 218 
ILE HG12 H N N 219 
ILE HG13 H N N 220 
ILE HG21 H N N 221 
ILE HG22 H N N 222 
ILE HG23 H N N 223 
ILE HD11 H N N 224 
ILE HD12 H N N 225 
ILE HD13 H N N 226 
ILE HXT  H N N 227 
LEU N    N N N 228 
LEU CA   C N S 229 
LEU C    C N N 230 
LEU O    O N N 231 
LEU CB   C N N 232 
LEU CG   C N N 233 
LEU CD1  C N N 234 
LEU CD2  C N N 235 
LEU OXT  O N N 236 
LEU H    H N N 237 
LEU H2   H N N 238 
LEU HA   H N N 239 
LEU HB2  H N N 240 
LEU HB3  H N N 241 
LEU HG   H N N 242 
LEU HD11 H N N 243 
LEU HD12 H N N 244 
LEU HD13 H N N 245 
LEU HD21 H N N 246 
LEU HD22 H N N 247 
LEU HD23 H N N 248 
LEU HXT  H N N 249 
LYS N    N N N 250 
LYS CA   C N S 251 
LYS C    C N N 252 
LYS O    O N N 253 
LYS CB   C N N 254 
LYS CG   C N N 255 
LYS CD   C N N 256 
LYS CE   C N N 257 
LYS NZ   N N N 258 
LYS OXT  O N N 259 
LYS H    H N N 260 
LYS H2   H N N 261 
LYS HA   H N N 262 
LYS HB2  H N N 263 
LYS HB3  H N N 264 
LYS HG2  H N N 265 
LYS HG3  H N N 266 
LYS HD2  H N N 267 
LYS HD3  H N N 268 
LYS HE2  H N N 269 
LYS HE3  H N N 270 
LYS HZ1  H N N 271 
LYS HZ2  H N N 272 
LYS HZ3  H N N 273 
LYS HXT  H N N 274 
MAN C1   C N S 275 
MAN C2   C N S 276 
MAN C3   C N S 277 
MAN C4   C N S 278 
MAN C5   C N R 279 
MAN C6   C N N 280 
MAN O1   O N N 281 
MAN O2   O N N 282 
MAN O3   O N N 283 
MAN O4   O N N 284 
MAN O5   O N N 285 
MAN O6   O N N 286 
MAN H1   H N N 287 
MAN H2   H N N 288 
MAN H3   H N N 289 
MAN H4   H N N 290 
MAN H5   H N N 291 
MAN H61  H N N 292 
MAN H62  H N N 293 
MAN HO1  H N N 294 
MAN HO2  H N N 295 
MAN HO3  H N N 296 
MAN HO4  H N N 297 
MAN HO6  H N N 298 
MET N    N N N 299 
MET CA   C N S 300 
MET C    C N N 301 
MET O    O N N 302 
MET CB   C N N 303 
MET CG   C N N 304 
MET SD   S N N 305 
MET CE   C N N 306 
MET OXT  O N N 307 
MET H    H N N 308 
MET H2   H N N 309 
MET HA   H N N 310 
MET HB2  H N N 311 
MET HB3  H N N 312 
MET HG2  H N N 313 
MET HG3  H N N 314 
MET HE1  H N N 315 
MET HE2  H N N 316 
MET HE3  H N N 317 
MET HXT  H N N 318 
NAG C1   C N R 319 
NAG C2   C N R 320 
NAG C3   C N R 321 
NAG C4   C N S 322 
NAG C5   C N R 323 
NAG C6   C N N 324 
NAG C7   C N N 325 
NAG C8   C N N 326 
NAG N2   N N N 327 
NAG O1   O N N 328 
NAG O3   O N N 329 
NAG O4   O N N 330 
NAG O5   O N N 331 
NAG O6   O N N 332 
NAG O7   O N N 333 
NAG H1   H N N 334 
NAG H2   H N N 335 
NAG H3   H N N 336 
NAG H4   H N N 337 
NAG H5   H N N 338 
NAG H61  H N N 339 
NAG H62  H N N 340 
NAG H81  H N N 341 
NAG H82  H N N 342 
NAG H83  H N N 343 
NAG HN2  H N N 344 
NAG HO1  H N N 345 
NAG HO3  H N N 346 
NAG HO4  H N N 347 
NAG HO6  H N N 348 
PHE N    N N N 349 
PHE CA   C N S 350 
PHE C    C N N 351 
PHE O    O N N 352 
PHE CB   C N N 353 
PHE CG   C Y N 354 
PHE CD1  C Y N 355 
PHE CD2  C Y N 356 
PHE CE1  C Y N 357 
PHE CE2  C Y N 358 
PHE CZ   C Y N 359 
PHE OXT  O N N 360 
PHE H    H N N 361 
PHE H2   H N N 362 
PHE HA   H N N 363 
PHE HB2  H N N 364 
PHE HB3  H N N 365 
PHE HD1  H N N 366 
PHE HD2  H N N 367 
PHE HE1  H N N 368 
PHE HE2  H N N 369 
PHE HZ   H N N 370 
PHE HXT  H N N 371 
PRO N    N N N 372 
PRO CA   C N S 373 
PRO C    C N N 374 
PRO O    O N N 375 
PRO CB   C N N 376 
PRO CG   C N N 377 
PRO CD   C N N 378 
PRO OXT  O N N 379 
PRO H    H N N 380 
PRO HA   H N N 381 
PRO HB2  H N N 382 
PRO HB3  H N N 383 
PRO HG2  H N N 384 
PRO HG3  H N N 385 
PRO HD2  H N N 386 
PRO HD3  H N N 387 
PRO HXT  H N N 388 
SER N    N N N 389 
SER CA   C N S 390 
SER C    C N N 391 
SER O    O N N 392 
SER CB   C N N 393 
SER OG   O N N 394 
SER OXT  O N N 395 
SER H    H N N 396 
SER H2   H N N 397 
SER HA   H N N 398 
SER HB2  H N N 399 
SER HB3  H N N 400 
SER HG   H N N 401 
SER HXT  H N N 402 
SIA C1   C N N 403 
SIA C2   C N R 404 
SIA C3   C N N 405 
SIA C4   C N S 406 
SIA C5   C N R 407 
SIA C6   C N R 408 
SIA C7   C N R 409 
SIA C8   C N R 410 
SIA C9   C N N 411 
SIA C10  C N N 412 
SIA C11  C N N 413 
SIA N5   N N N 414 
SIA O1A  O N N 415 
SIA O1B  O N N 416 
SIA O2   O N N 417 
SIA O4   O N N 418 
SIA O6   O N N 419 
SIA O7   O N N 420 
SIA O8   O N N 421 
SIA O9   O N N 422 
SIA O10  O N N 423 
SIA H32  H N N 424 
SIA H31  H N N 425 
SIA H4   H N N 426 
SIA H5   H N N 427 
SIA H6   H N N 428 
SIA H7   H N N 429 
SIA H8   H N N 430 
SIA H92  H N N 431 
SIA H91  H N N 432 
SIA H111 H N N 433 
SIA H113 H N N 434 
SIA H112 H N N 435 
SIA HN5  H N N 436 
SIA HO1B H N N 437 
SIA HO2  H N N 438 
SIA HO4  H N N 439 
SIA HO7  H N N 440 
SIA HO8  H N N 441 
SIA HO9  H N N 442 
THR N    N N N 443 
THR CA   C N S 444 
THR C    C N N 445 
THR O    O N N 446 
THR CB   C N R 447 
THR OG1  O N N 448 
THR CG2  C N N 449 
THR OXT  O N N 450 
THR H    H N N 451 
THR H2   H N N 452 
THR HA   H N N 453 
THR HB   H N N 454 
THR HG1  H N N 455 
THR HG21 H N N 456 
THR HG22 H N N 457 
THR HG23 H N N 458 
THR HXT  H N N 459 
TRP N    N N N 460 
TRP CA   C N S 461 
TRP C    C N N 462 
TRP O    O N N 463 
TRP CB   C N N 464 
TRP CG   C Y N 465 
TRP CD1  C Y N 466 
TRP CD2  C Y N 467 
TRP NE1  N Y N 468 
TRP CE2  C Y N 469 
TRP CE3  C Y N 470 
TRP CZ2  C Y N 471 
TRP CZ3  C Y N 472 
TRP CH2  C Y N 473 
TRP OXT  O N N 474 
TRP H    H N N 475 
TRP H2   H N N 476 
TRP HA   H N N 477 
TRP HB2  H N N 478 
TRP HB3  H N N 479 
TRP HD1  H N N 480 
TRP HE1  H N N 481 
TRP HE3  H N N 482 
TRP HZ2  H N N 483 
TRP HZ3  H N N 484 
TRP HH2  H N N 485 
TRP HXT  H N N 486 
TYR N    N N N 487 
TYR CA   C N S 488 
TYR C    C N N 489 
TYR O    O N N 490 
TYR CB   C N N 491 
TYR CG   C Y N 492 
TYR CD1  C Y N 493 
TYR CD2  C Y N 494 
TYR CE1  C Y N 495 
TYR CE2  C Y N 496 
TYR CZ   C Y N 497 
TYR OH   O N N 498 
TYR OXT  O N N 499 
TYR H    H N N 500 
TYR H2   H N N 501 
TYR HA   H N N 502 
TYR HB2  H N N 503 
TYR HB3  H N N 504 
TYR HD1  H N N 505 
TYR HD2  H N N 506 
TYR HE1  H N N 507 
TYR HE2  H N N 508 
TYR HH   H N N 509 
TYR HXT  H N N 510 
VAL N    N N N 511 
VAL CA   C N S 512 
VAL C    C N N 513 
VAL O    O N N 514 
VAL CB   C N N 515 
VAL CG1  C N N 516 
VAL CG2  C N N 517 
VAL OXT  O N N 518 
VAL H    H N N 519 
VAL H2   H N N 520 
VAL HA   H N N 521 
VAL HB   H N N 522 
VAL HG11 H N N 523 
VAL HG12 H N N 524 
VAL HG13 H N N 525 
VAL HG21 H N N 526 
VAL HG22 H N N 527 
VAL HG23 H N N 528 
VAL HXT  H N N 529 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GAL C1  C2   sing N N 107 
GAL C1  O1   sing N N 108 
GAL C1  O5   sing N N 109 
GAL C1  H1   sing N N 110 
GAL C2  C3   sing N N 111 
GAL C2  O2   sing N N 112 
GAL C2  H2   sing N N 113 
GAL C3  C4   sing N N 114 
GAL C3  O3   sing N N 115 
GAL C3  H3   sing N N 116 
GAL C4  C5   sing N N 117 
GAL C4  O4   sing N N 118 
GAL C4  H4   sing N N 119 
GAL C5  C6   sing N N 120 
GAL C5  O5   sing N N 121 
GAL C5  H5   sing N N 122 
GAL C6  O6   sing N N 123 
GAL C6  H61  sing N N 124 
GAL C6  H62  sing N N 125 
GAL O1  HO1  sing N N 126 
GAL O2  HO2  sing N N 127 
GAL O3  HO3  sing N N 128 
GAL O4  HO4  sing N N 129 
GAL O6  HO6  sing N N 130 
GLN N   CA   sing N N 131 
GLN N   H    sing N N 132 
GLN N   H2   sing N N 133 
GLN CA  C    sing N N 134 
GLN CA  CB   sing N N 135 
GLN CA  HA   sing N N 136 
GLN C   O    doub N N 137 
GLN C   OXT  sing N N 138 
GLN CB  CG   sing N N 139 
GLN CB  HB2  sing N N 140 
GLN CB  HB3  sing N N 141 
GLN CG  CD   sing N N 142 
GLN CG  HG2  sing N N 143 
GLN CG  HG3  sing N N 144 
GLN CD  OE1  doub N N 145 
GLN CD  NE2  sing N N 146 
GLN NE2 HE21 sing N N 147 
GLN NE2 HE22 sing N N 148 
GLN OXT HXT  sing N N 149 
GLU N   CA   sing N N 150 
GLU N   H    sing N N 151 
GLU N   H2   sing N N 152 
GLU CA  C    sing N N 153 
GLU CA  CB   sing N N 154 
GLU CA  HA   sing N N 155 
GLU C   O    doub N N 156 
GLU C   OXT  sing N N 157 
GLU CB  CG   sing N N 158 
GLU CB  HB2  sing N N 159 
GLU CB  HB3  sing N N 160 
GLU CG  CD   sing N N 161 
GLU CG  HG2  sing N N 162 
GLU CG  HG3  sing N N 163 
GLU CD  OE1  doub N N 164 
GLU CD  OE2  sing N N 165 
GLU OE2 HE2  sing N N 166 
GLU OXT HXT  sing N N 167 
GLY N   CA   sing N N 168 
GLY N   H    sing N N 169 
GLY N   H2   sing N N 170 
GLY CA  C    sing N N 171 
GLY CA  HA2  sing N N 172 
GLY CA  HA3  sing N N 173 
GLY C   O    doub N N 174 
GLY C   OXT  sing N N 175 
GLY OXT HXT  sing N N 176 
HIS N   CA   sing N N 177 
HIS N   H    sing N N 178 
HIS N   H2   sing N N 179 
HIS CA  C    sing N N 180 
HIS CA  CB   sing N N 181 
HIS CA  HA   sing N N 182 
HIS C   O    doub N N 183 
HIS C   OXT  sing N N 184 
HIS CB  CG   sing N N 185 
HIS CB  HB2  sing N N 186 
HIS CB  HB3  sing N N 187 
HIS CG  ND1  sing Y N 188 
HIS CG  CD2  doub Y N 189 
HIS ND1 CE1  doub Y N 190 
HIS ND1 HD1  sing N N 191 
HIS CD2 NE2  sing Y N 192 
HIS CD2 HD2  sing N N 193 
HIS CE1 NE2  sing Y N 194 
HIS CE1 HE1  sing N N 195 
HIS NE2 HE2  sing N N 196 
HIS OXT HXT  sing N N 197 
ILE N   CA   sing N N 198 
ILE N   H    sing N N 199 
ILE N   H2   sing N N 200 
ILE CA  C    sing N N 201 
ILE CA  CB   sing N N 202 
ILE CA  HA   sing N N 203 
ILE C   O    doub N N 204 
ILE C   OXT  sing N N 205 
ILE CB  CG1  sing N N 206 
ILE CB  CG2  sing N N 207 
ILE CB  HB   sing N N 208 
ILE CG1 CD1  sing N N 209 
ILE CG1 HG12 sing N N 210 
ILE CG1 HG13 sing N N 211 
ILE CG2 HG21 sing N N 212 
ILE CG2 HG22 sing N N 213 
ILE CG2 HG23 sing N N 214 
ILE CD1 HD11 sing N N 215 
ILE CD1 HD12 sing N N 216 
ILE CD1 HD13 sing N N 217 
ILE OXT HXT  sing N N 218 
LEU N   CA   sing N N 219 
LEU N   H    sing N N 220 
LEU N   H2   sing N N 221 
LEU CA  C    sing N N 222 
LEU CA  CB   sing N N 223 
LEU CA  HA   sing N N 224 
LEU C   O    doub N N 225 
LEU C   OXT  sing N N 226 
LEU CB  CG   sing N N 227 
LEU CB  HB2  sing N N 228 
LEU CB  HB3  sing N N 229 
LEU CG  CD1  sing N N 230 
LEU CG  CD2  sing N N 231 
LEU CG  HG   sing N N 232 
LEU CD1 HD11 sing N N 233 
LEU CD1 HD12 sing N N 234 
LEU CD1 HD13 sing N N 235 
LEU CD2 HD21 sing N N 236 
LEU CD2 HD22 sing N N 237 
LEU CD2 HD23 sing N N 238 
LEU OXT HXT  sing N N 239 
LYS N   CA   sing N N 240 
LYS N   H    sing N N 241 
LYS N   H2   sing N N 242 
LYS CA  C    sing N N 243 
LYS CA  CB   sing N N 244 
LYS CA  HA   sing N N 245 
LYS C   O    doub N N 246 
LYS C   OXT  sing N N 247 
LYS CB  CG   sing N N 248 
LYS CB  HB2  sing N N 249 
LYS CB  HB3  sing N N 250 
LYS CG  CD   sing N N 251 
LYS CG  HG2  sing N N 252 
LYS CG  HG3  sing N N 253 
LYS CD  CE   sing N N 254 
LYS CD  HD2  sing N N 255 
LYS CD  HD3  sing N N 256 
LYS CE  NZ   sing N N 257 
LYS CE  HE2  sing N N 258 
LYS CE  HE3  sing N N 259 
LYS NZ  HZ1  sing N N 260 
LYS NZ  HZ2  sing N N 261 
LYS NZ  HZ3  sing N N 262 
LYS OXT HXT  sing N N 263 
MAN C1  C2   sing N N 264 
MAN C1  O1   sing N N 265 
MAN C1  O5   sing N N 266 
MAN C1  H1   sing N N 267 
MAN C2  C3   sing N N 268 
MAN C2  O2   sing N N 269 
MAN C2  H2   sing N N 270 
MAN C3  C4   sing N N 271 
MAN C3  O3   sing N N 272 
MAN C3  H3   sing N N 273 
MAN C4  C5   sing N N 274 
MAN C4  O4   sing N N 275 
MAN C4  H4   sing N N 276 
MAN C5  C6   sing N N 277 
MAN C5  O5   sing N N 278 
MAN C5  H5   sing N N 279 
MAN C6  O6   sing N N 280 
MAN C6  H61  sing N N 281 
MAN C6  H62  sing N N 282 
MAN O1  HO1  sing N N 283 
MAN O2  HO2  sing N N 284 
MAN O3  HO3  sing N N 285 
MAN O4  HO4  sing N N 286 
MAN O6  HO6  sing N N 287 
MET N   CA   sing N N 288 
MET N   H    sing N N 289 
MET N   H2   sing N N 290 
MET CA  C    sing N N 291 
MET CA  CB   sing N N 292 
MET CA  HA   sing N N 293 
MET C   O    doub N N 294 
MET C   OXT  sing N N 295 
MET CB  CG   sing N N 296 
MET CB  HB2  sing N N 297 
MET CB  HB3  sing N N 298 
MET CG  SD   sing N N 299 
MET CG  HG2  sing N N 300 
MET CG  HG3  sing N N 301 
MET SD  CE   sing N N 302 
MET CE  HE1  sing N N 303 
MET CE  HE2  sing N N 304 
MET CE  HE3  sing N N 305 
MET OXT HXT  sing N N 306 
NAG C1  C2   sing N N 307 
NAG C1  O1   sing N N 308 
NAG C1  O5   sing N N 309 
NAG C1  H1   sing N N 310 
NAG C2  C3   sing N N 311 
NAG C2  N2   sing N N 312 
NAG C2  H2   sing N N 313 
NAG C3  C4   sing N N 314 
NAG C3  O3   sing N N 315 
NAG C3  H3   sing N N 316 
NAG C4  C5   sing N N 317 
NAG C4  O4   sing N N 318 
NAG C4  H4   sing N N 319 
NAG C5  C6   sing N N 320 
NAG C5  O5   sing N N 321 
NAG C5  H5   sing N N 322 
NAG C6  O6   sing N N 323 
NAG C6  H61  sing N N 324 
NAG C6  H62  sing N N 325 
NAG C7  C8   sing N N 326 
NAG C7  N2   sing N N 327 
NAG C7  O7   doub N N 328 
NAG C8  H81  sing N N 329 
NAG C8  H82  sing N N 330 
NAG C8  H83  sing N N 331 
NAG N2  HN2  sing N N 332 
NAG O1  HO1  sing N N 333 
NAG O3  HO3  sing N N 334 
NAG O4  HO4  sing N N 335 
NAG O6  HO6  sing N N 336 
PHE N   CA   sing N N 337 
PHE N   H    sing N N 338 
PHE N   H2   sing N N 339 
PHE CA  C    sing N N 340 
PHE CA  CB   sing N N 341 
PHE CA  HA   sing N N 342 
PHE C   O    doub N N 343 
PHE C   OXT  sing N N 344 
PHE CB  CG   sing N N 345 
PHE CB  HB2  sing N N 346 
PHE CB  HB3  sing N N 347 
PHE CG  CD1  doub Y N 348 
PHE CG  CD2  sing Y N 349 
PHE CD1 CE1  sing Y N 350 
PHE CD1 HD1  sing N N 351 
PHE CD2 CE2  doub Y N 352 
PHE CD2 HD2  sing N N 353 
PHE CE1 CZ   doub Y N 354 
PHE CE1 HE1  sing N N 355 
PHE CE2 CZ   sing Y N 356 
PHE CE2 HE2  sing N N 357 
PHE CZ  HZ   sing N N 358 
PHE OXT HXT  sing N N 359 
PRO N   CA   sing N N 360 
PRO N   CD   sing N N 361 
PRO N   H    sing N N 362 
PRO CA  C    sing N N 363 
PRO CA  CB   sing N N 364 
PRO CA  HA   sing N N 365 
PRO C   O    doub N N 366 
PRO C   OXT  sing N N 367 
PRO CB  CG   sing N N 368 
PRO CB  HB2  sing N N 369 
PRO CB  HB3  sing N N 370 
PRO CG  CD   sing N N 371 
PRO CG  HG2  sing N N 372 
PRO CG  HG3  sing N N 373 
PRO CD  HD2  sing N N 374 
PRO CD  HD3  sing N N 375 
PRO OXT HXT  sing N N 376 
SER N   CA   sing N N 377 
SER N   H    sing N N 378 
SER N   H2   sing N N 379 
SER CA  C    sing N N 380 
SER CA  CB   sing N N 381 
SER CA  HA   sing N N 382 
SER C   O    doub N N 383 
SER C   OXT  sing N N 384 
SER CB  OG   sing N N 385 
SER CB  HB2  sing N N 386 
SER CB  HB3  sing N N 387 
SER OG  HG   sing N N 388 
SER OXT HXT  sing N N 389 
SIA C1  C2   sing N N 390 
SIA C1  O1A  doub N N 391 
SIA C1  O1B  sing N N 392 
SIA C2  C3   sing N N 393 
SIA C2  O2   sing N N 394 
SIA C2  O6   sing N N 395 
SIA C3  C4   sing N N 396 
SIA C3  H32  sing N N 397 
SIA C3  H31  sing N N 398 
SIA C4  C5   sing N N 399 
SIA C4  O4   sing N N 400 
SIA C4  H4   sing N N 401 
SIA C5  C6   sing N N 402 
SIA C5  N5   sing N N 403 
SIA C5  H5   sing N N 404 
SIA C6  C7   sing N N 405 
SIA C6  O6   sing N N 406 
SIA C6  H6   sing N N 407 
SIA C7  C8   sing N N 408 
SIA C7  O7   sing N N 409 
SIA C7  H7   sing N N 410 
SIA C8  C9   sing N N 411 
SIA C8  O8   sing N N 412 
SIA C8  H8   sing N N 413 
SIA C9  O9   sing N N 414 
SIA C9  H92  sing N N 415 
SIA C9  H91  sing N N 416 
SIA C10 C11  sing N N 417 
SIA C10 N5   sing N N 418 
SIA C10 O10  doub N N 419 
SIA C11 H111 sing N N 420 
SIA C11 H113 sing N N 421 
SIA C11 H112 sing N N 422 
SIA N5  HN5  sing N N 423 
SIA O1B HO1B sing N N 424 
SIA O2  HO2  sing N N 425 
SIA O4  HO4  sing N N 426 
SIA O7  HO7  sing N N 427 
SIA O8  HO8  sing N N 428 
SIA O9  HO9  sing N N 429 
THR N   CA   sing N N 430 
THR N   H    sing N N 431 
THR N   H2   sing N N 432 
THR CA  C    sing N N 433 
THR CA  CB   sing N N 434 
THR CA  HA   sing N N 435 
THR C   O    doub N N 436 
THR C   OXT  sing N N 437 
THR CB  OG1  sing N N 438 
THR CB  CG2  sing N N 439 
THR CB  HB   sing N N 440 
THR OG1 HG1  sing N N 441 
THR CG2 HG21 sing N N 442 
THR CG2 HG22 sing N N 443 
THR CG2 HG23 sing N N 444 
THR OXT HXT  sing N N 445 
TRP N   CA   sing N N 446 
TRP N   H    sing N N 447 
TRP N   H2   sing N N 448 
TRP CA  C    sing N N 449 
TRP CA  CB   sing N N 450 
TRP CA  HA   sing N N 451 
TRP C   O    doub N N 452 
TRP C   OXT  sing N N 453 
TRP CB  CG   sing N N 454 
TRP CB  HB2  sing N N 455 
TRP CB  HB3  sing N N 456 
TRP CG  CD1  doub Y N 457 
TRP CG  CD2  sing Y N 458 
TRP CD1 NE1  sing Y N 459 
TRP CD1 HD1  sing N N 460 
TRP CD2 CE2  doub Y N 461 
TRP CD2 CE3  sing Y N 462 
TRP NE1 CE2  sing Y N 463 
TRP NE1 HE1  sing N N 464 
TRP CE2 CZ2  sing Y N 465 
TRP CE3 CZ3  doub Y N 466 
TRP CE3 HE3  sing N N 467 
TRP CZ2 CH2  doub Y N 468 
TRP CZ2 HZ2  sing N N 469 
TRP CZ3 CH2  sing Y N 470 
TRP CZ3 HZ3  sing N N 471 
TRP CH2 HH2  sing N N 472 
TRP OXT HXT  sing N N 473 
TYR N   CA   sing N N 474 
TYR N   H    sing N N 475 
TYR N   H2   sing N N 476 
TYR CA  C    sing N N 477 
TYR CA  CB   sing N N 478 
TYR CA  HA   sing N N 479 
TYR C   O    doub N N 480 
TYR C   OXT  sing N N 481 
TYR CB  CG   sing N N 482 
TYR CB  HB2  sing N N 483 
TYR CB  HB3  sing N N 484 
TYR CG  CD1  doub Y N 485 
TYR CG  CD2  sing Y N 486 
TYR CD1 CE1  sing Y N 487 
TYR CD1 HD1  sing N N 488 
TYR CD2 CE2  doub Y N 489 
TYR CD2 HD2  sing N N 490 
TYR CE1 CZ   doub Y N 491 
TYR CE1 HE1  sing N N 492 
TYR CE2 CZ   sing Y N 493 
TYR CE2 HE2  sing N N 494 
TYR CZ  OH   sing N N 495 
TYR OH  HH   sing N N 496 
TYR OXT HXT  sing N N 497 
VAL N   CA   sing N N 498 
VAL N   H    sing N N 499 
VAL N   H2   sing N N 500 
VAL CA  C    sing N N 501 
VAL CA  CB   sing N N 502 
VAL CA  HA   sing N N 503 
VAL C   O    doub N N 504 
VAL C   OXT  sing N N 505 
VAL CB  CG1  sing N N 506 
VAL CB  CG2  sing N N 507 
VAL CB  HB   sing N N 508 
VAL CG1 HG11 sing N N 509 
VAL CG1 HG12 sing N N 510 
VAL CG1 HG13 sing N N 511 
VAL CG2 HG21 sing N N 512 
VAL CG2 HG22 sing N N 513 
VAL CG2 HG23 sing N N 514 
VAL OXT HXT  sing N N 515 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-12 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZW6 
_em_admin.last_update        2025-02-19 
_em_admin.map_release_date   2025-02-19 
_em_admin.title              
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus S228 mutant complexed with avian receptor analog LSTa' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          11320 
_em_entity_assembly_naturalsource.organism             'Influenza A virus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.0 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
2 BMA 3 n 
2 MAN 4 n 
2 MAN 5 n 
3 NAG 1 n 
3 NAG 2 n 
4 GAL 1 n 
4 SIA 2 n 
# 
_atom_sites.entry_id                    8ZW6 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . THR A 1 12  ? 153.236 137.013 201.320 1.00 90.30  ? 12  THR A N   1 
ATOM   2     C CA  . THR A 1 12  ? 152.473 137.108 200.081 1.00 90.30  ? 12  THR A CA  1 
ATOM   3     C C   . THR A 1 12  ? 153.339 136.763 198.875 1.00 90.30  ? 12  THR A C   1 
ATOM   4     O O   . THR A 1 12  ? 154.520 136.446 199.016 1.00 90.30  ? 12  THR A O   1 
ATOM   5     C CB  . THR A 1 12  ? 151.882 138.516 199.888 1.00 90.30  ? 12  THR A CB  1 
ATOM   6     O OG1 . THR A 1 12  ? 152.944 139.460 199.705 1.00 90.30  ? 12  THR A OG1 1 
ATOM   7     C CG2 . THR A 1 12  ? 151.060 138.917 201.101 1.00 90.30  ? 12  THR A CG2 1 
ATOM   8     N N   . ALA A 1 13  ? 152.742 136.828 197.688 1.00 87.27  ? 13  ALA A N   1 
ATOM   9     C CA  . ALA A 1 13  ? 153.455 136.526 196.456 1.00 87.27  ? 13  ALA A CA  1 
ATOM   10    C C   . ALA A 1 13  ? 152.752 137.221 195.301 1.00 87.27  ? 13  ALA A C   1 
ATOM   11    O O   . ALA A 1 13  ? 151.608 137.664 195.422 1.00 87.27  ? 13  ALA A O   1 
ATOM   12    C CB  . ALA A 1 13  ? 153.541 135.016 196.209 1.00 87.27  ? 13  ALA A CB  1 
ATOM   13    N N   . THR A 1 14  ? 153.459 137.313 194.177 1.00 81.87  ? 14  THR A N   1 
ATOM   14    C CA  . THR A 1 14  ? 152.938 137.927 192.966 1.00 81.87  ? 14  THR A CA  1 
ATOM   15    C C   . THR A 1 14  ? 153.179 136.993 191.790 1.00 81.87  ? 14  THR A C   1 
ATOM   16    O O   . THR A 1 14  ? 154.255 136.403 191.669 1.00 81.87  ? 14  THR A O   1 
ATOM   17    C CB  . THR A 1 14  ? 153.599 139.288 192.698 1.00 81.87  ? 14  THR A CB  1 
ATOM   18    O OG1 . THR A 1 14  ? 153.439 140.132 193.845 1.00 81.87  ? 14  THR A OG1 1 
ATOM   19    C CG2 . THR A 1 14  ? 152.967 139.963 191.491 1.00 81.87  ? 14  THR A CG2 1 
ATOM   20    N N   . LEU A 1 15  ? 152.169 136.850 190.933 1.00 76.48  ? 15  LEU A N   1 
ATOM   21    C CA  . LEU A 1 15  ? 152.262 136.022 189.737 1.00 76.48  ? 15  LEU A CA  1 
ATOM   22    C C   . LEU A 1 15  ? 151.766 136.833 188.551 1.00 76.48  ? 15  LEU A C   1 
ATOM   23    O O   . LEU A 1 15  ? 150.654 137.368 188.588 1.00 76.48  ? 15  LEU A O   1 
ATOM   24    C CB  . LEU A 1 15  ? 151.448 134.734 189.891 1.00 76.48  ? 15  LEU A CB  1 
ATOM   25    C CG  . LEU A 1 15  ? 151.569 133.705 188.767 1.00 76.48  ? 15  LEU A CG  1 
ATOM   26    C CD1 . LEU A 1 15  ? 152.957 133.090 188.752 1.00 76.48  ? 15  LEU A CD1 1 
ATOM   27    C CD2 . LEU A 1 15  ? 150.507 132.630 188.914 1.00 76.48  ? 15  LEU A CD2 1 
ATOM   28    N N   . CYS A 1 16  ? 152.582 136.917 187.504 1.00 72.95  ? 16  CYS A N   1 
ATOM   29    C CA  . CYS A 1 16  ? 152.283 137.731 186.334 1.00 72.95  ? 16  CYS A CA  1 
ATOM   30    C C   . CYS A 1 16  ? 152.336 136.878 185.075 1.00 72.95  ? 16  CYS A C   1 
ATOM   31    O O   . CYS A 1 16  ? 153.172 135.976 184.959 1.00 72.95  ? 16  CYS A O   1 
ATOM   32    C CB  . CYS A 1 16  ? 153.266 138.899 186.210 1.00 72.95  ? 16  CYS A CB  1 
ATOM   33    S SG  . CYS A 1 16  ? 153.159 140.114 187.544 1.00 72.95  ? 16  CYS A SG  1 
ATOM   34    N N   . LEU A 1 17  ? 151.440 137.169 184.136 1.00 67.13  ? 17  LEU A N   1 
ATOM   35    C CA  . LEU A 1 17  ? 151.384 136.490 182.849 1.00 67.13  ? 17  LEU A CA  1 
ATOM   36    C C   . LEU A 1 17  ? 151.680 137.489 181.741 1.00 67.13  ? 17  LEU A C   1 
ATOM   37    O O   . LEU A 1 17  ? 151.275 138.653 181.820 1.00 67.13  ? 17  LEU A O   1 
ATOM   38    C CB  . LEU A 1 17  ? 150.015 135.840 182.616 1.00 67.13  ? 17  LEU A CB  1 
ATOM   39    C CG  . LEU A 1 17  ? 149.721 134.520 183.333 1.00 67.13  ? 17  LEU A CG  1 
ATOM   40    C CD1 . LEU A 1 17  ? 149.397 134.744 184.803 1.00 67.13  ? 17  LEU A CD1 1 
ATOM   41    C CD2 . LEU A 1 17  ? 148.594 133.778 182.640 1.00 67.13  ? 17  LEU A CD2 1 
ATOM   42    N N   . GLY A 1 18  ? 152.385 137.035 180.708 1.00 63.53  ? 18  GLY A N   1 
ATOM   43    C CA  . GLY A 1 18  ? 152.771 137.934 179.639 1.00 63.53  ? 18  GLY A CA  1 
ATOM   44    C C   . GLY A 1 18  ? 153.142 137.184 178.379 1.00 63.53  ? 18  GLY A C   1 
ATOM   45    O O   . GLY A 1 18  ? 153.014 135.962 178.290 1.00 63.53  ? 18  GLY A O   1 
ATOM   46    N N   . HIS A 1 19  ? 153.610 137.950 177.395 1.00 60.13  ? 19  HIS A N   1 
ATOM   47    C CA  . HIS A 1 19  ? 153.992 137.422 176.093 1.00 60.13  ? 19  HIS A CA  1 
ATOM   48    C C   . HIS A 1 19  ? 155.282 138.094 175.646 1.00 60.13  ? 19  HIS A C   1 
ATOM   49    O O   . HIS A 1 19  ? 155.679 139.133 176.177 1.00 60.13  ? 19  HIS A O   1 
ATOM   50    C CB  . HIS A 1 19  ? 152.883 137.633 175.054 1.00 60.13  ? 19  HIS A CB  1 
ATOM   51    C CG  . HIS A 1 19  ? 152.414 139.050 174.950 1.00 60.13  ? 19  HIS A CG  1 
ATOM   52    N ND1 . HIS A 1 19  ? 153.115 140.019 174.266 1.00 60.13  ? 19  HIS A ND1 1 
ATOM   53    C CD2 . HIS A 1 19  ? 151.314 139.663 175.446 1.00 60.13  ? 19  HIS A CD2 1 
ATOM   54    C CE1 . HIS A 1 19  ? 152.467 141.167 174.343 1.00 60.13  ? 19  HIS A CE1 1 
ATOM   55    N NE2 . HIS A 1 19  ? 151.370 140.979 175.055 1.00 60.13  ? 19  HIS A NE2 1 
ATOM   56    N N   . HIS A 1 20  ? 155.937 137.489 174.657 1.00 59.75  ? 20  HIS A N   1 
ATOM   57    C CA  . HIS A 1 20  ? 157.255 137.946 174.248 1.00 59.75  ? 20  HIS A CA  1 
ATOM   58    C C   . HIS A 1 20  ? 157.146 139.209 173.397 1.00 59.75  ? 20  HIS A C   1 
ATOM   59    O O   . HIS A 1 20  ? 156.057 139.687 173.068 1.00 59.75  ? 20  HIS A O   1 
ATOM   60    C CB  . HIS A 1 20  ? 157.996 136.857 173.475 1.00 59.75  ? 20  HIS A CB  1 
ATOM   61    C CG  . HIS A 1 20  ? 157.333 136.466 172.191 1.00 59.75  ? 20  HIS A CG  1 
ATOM   62    N ND1 . HIS A 1 20  ? 156.446 135.415 172.104 1.00 59.75  ? 20  HIS A ND1 1 
ATOM   63    C CD2 . HIS A 1 20  ? 157.423 136.984 170.944 1.00 59.75  ? 20  HIS A CD2 1 
ATOM   64    C CE1 . HIS A 1 20  ? 156.019 135.302 170.860 1.00 59.75  ? 20  HIS A CE1 1 
ATOM   65    N NE2 . HIS A 1 20  ? 156.596 136.243 170.135 1.00 59.75  ? 20  HIS A NE2 1 
ATOM   66    N N   . SER A 1 21  ? 158.304 139.756 173.038 1.00 58.21  ? 21  SER A N   1 
ATOM   67    C CA  . SER A 1 21  ? 158.391 140.885 172.126 1.00 58.21  ? 21  SER A CA  1 
ATOM   68    C C   . SER A 1 21  ? 159.724 140.805 171.398 1.00 58.21  ? 21  SER A C   1 
ATOM   69    O O   . SER A 1 21  ? 160.667 140.161 171.864 1.00 58.21  ? 21  SER A O   1 
ATOM   70    C CB  . SER A 1 21  ? 158.249 142.220 172.866 1.00 58.21  ? 21  SER A CB  1 
ATOM   71    O OG  . SER A 1 21  ? 158.297 143.311 171.965 1.00 58.21  ? 21  SER A OG  1 
ATOM   72    N N   . VAL A 1 22  ? 159.794 141.462 170.245 1.00 54.62  ? 22  VAL A N   1 
ATOM   73    C CA  . VAL A 1 22  ? 161.020 141.467 169.449 1.00 54.62  ? 22  VAL A CA  1 
ATOM   74    C C   . VAL A 1 22  ? 161.486 142.907 169.269 1.00 54.62  ? 22  VAL A C   1 
ATOM   75    O O   . VAL A 1 22  ? 160.658 143.829 169.259 1.00 54.62  ? 22  VAL A O   1 
ATOM   76    C CB  . VAL A 1 22  ? 160.815 140.767 168.095 1.00 54.62  ? 22  VAL A CB  1 
ATOM   77    C CG1 . VAL A 1 22  ? 160.431 139.311 168.303 1.00 54.62  ? 22  VAL A CG1 1 
ATOM   78    C CG2 . VAL A 1 22  ? 159.765 141.487 167.269 1.00 54.62  ? 22  VAL A CG2 1 
ATOM   79    N N   . PRO A 1 23  ? 162.794 143.149 169.147 1.00 56.41  ? 23  PRO A N   1 
ATOM   80    C CA  . PRO A 1 23  ? 163.266 144.534 168.982 1.00 56.41  ? 23  PRO A CA  1 
ATOM   81    C C   . PRO A 1 23  ? 162.812 145.190 167.688 1.00 56.41  ? 23  PRO A C   1 
ATOM   82    O O   . PRO A 1 23  ? 162.762 146.424 167.620 1.00 56.41  ? 23  PRO A O   1 
ATOM   83    C CB  . PRO A 1 23  ? 164.795 144.393 169.037 1.00 56.41  ? 23  PRO A CB  1 
ATOM   84    C CG  . PRO A 1 23  ? 165.068 142.957 168.734 1.00 56.41  ? 23  PRO A CG  1 
ATOM   85    C CD  . PRO A 1 23  ? 163.905 142.191 169.270 1.00 56.41  ? 23  PRO A CD  1 
ATOM   86    N N   . ASN A 1 24  ? 162.480 144.410 166.661 1.00 55.29  ? 24  ASN A N   1 
ATOM   87    C CA  . ASN A 1 24  ? 162.099 144.950 165.360 1.00 55.29  ? 24  ASN A CA  1 
ATOM   88    C C   . ASN A 1 24  ? 160.855 144.234 164.861 1.00 55.29  ? 24  ASN A C   1 
ATOM   89    O O   . ASN A 1 24  ? 160.887 143.022 164.621 1.00 55.29  ? 24  ASN A O   1 
ATOM   90    C CB  . ASN A 1 24  ? 163.243 144.809 164.352 1.00 55.29  ? 24  ASN A CB  1 
ATOM   91    C CG  . ASN A 1 24  ? 163.861 143.425 164.362 1.00 55.29  ? 24  ASN A CG  1 
ATOM   92    O OD1 . ASN A 1 24  ? 163.617 142.630 165.269 1.00 55.29  ? 24  ASN A OD1 1 
ATOM   93    N ND2 . ASN A 1 24  ? 164.667 143.130 163.349 1.00 55.29  ? 24  ASN A ND2 1 
ATOM   94    N N   . GLY A 1 25  ? 159.765 144.982 164.695 1.00 49.58  ? 25  GLY A N   1 
ATOM   95    C CA  . GLY A 1 25  ? 158.525 144.432 164.199 1.00 49.58  ? 25  GLY A CA  1 
ATOM   96    C C   . GLY A 1 25  ? 158.303 144.733 162.723 1.00 49.58  ? 25  GLY A C   1 
ATOM   97    O O   . GLY A 1 25  ? 159.062 145.453 162.081 1.00 49.58  ? 25  GLY A O   1 
ATOM   98    N N   . THR A 1 26  ? 157.227 144.158 162.193 1.00 45.05  ? 26  THR A N   1 
ATOM   99    C CA  . THR A 1 26  ? 156.847 144.326 160.798 1.00 45.05  ? 26  THR A CA  1 
ATOM   100   C C   . THR A 1 26  ? 155.412 144.824 160.729 1.00 45.05  ? 26  THR A C   1 
ATOM   101   O O   . THR A 1 26  ? 154.551 144.365 161.485 1.00 45.05  ? 26  THR A O   1 
ATOM   102   C CB  . THR A 1 26  ? 156.993 143.010 160.020 1.00 45.05  ? 26  THR A CB  1 
ATOM   103   O OG1 . THR A 1 26  ? 158.355 142.573 160.073 1.00 45.05  ? 26  THR A OG1 1 
ATOM   104   C CG2 . THR A 1 26  ? 156.594 143.196 158.564 1.00 45.05  ? 26  THR A CG2 1 
ATOM   105   N N   . ILE A 1 27  ? 155.160 145.766 159.827 1.00 42.79  ? 27  ILE A N   1 
ATOM   106   C CA  . ILE A 1 27  ? 153.840 146.365 159.670 1.00 42.79  ? 27  ILE A CA  1 
ATOM   107   C C   . ILE A 1 27  ? 153.029 145.538 158.682 1.00 42.79  ? 27  ILE A C   1 
ATOM   108   O O   . ILE A 1 27  ? 153.491 145.247 157.572 1.00 42.79  ? 27  ILE A O   1 
ATOM   109   C CB  . ILE A 1 27  ? 153.953 147.824 159.198 1.00 42.79  ? 27  ILE A CB  1 
ATOM   110   C CG1 . ILE A 1 27  ? 154.759 148.654 160.200 1.00 42.79  ? 27  ILE A CG1 1 
ATOM   111   C CG2 . ILE A 1 27  ? 152.575 148.424 158.995 1.00 42.79  ? 27  ILE A CG2 1 
ATOM   112   C CD1 . ILE A 1 27  ? 154.145 148.718 161.578 1.00 42.79  ? 27  ILE A CD1 1 
ATOM   113   N N   . VAL A 1 28  ? 151.816 145.156 159.084 1.00 40.62  ? 28  VAL A N   1 
ATOM   114   C CA  . VAL A 1 28  ? 150.872 144.463 158.219 1.00 40.62  ? 28  VAL A CA  1 
ATOM   115   C C   . VAL A 1 28  ? 149.550 145.221 158.249 1.00 40.62  ? 28  VAL A C   1 
ATOM   116   O O   . VAL A 1 28  ? 149.371 146.175 159.005 1.00 40.62  ? 28  VAL A O   1 
ATOM   117   C CB  . VAL A 1 28  ? 150.666 142.988 158.623 1.00 40.62  ? 28  VAL A CB  1 
ATOM   118   C CG1 . VAL A 1 28  ? 151.962 142.209 158.476 1.00 40.62  ? 28  VAL A CG1 1 
ATOM   119   C CG2 . VAL A 1 28  ? 150.140 142.891 160.041 1.00 40.62  ? 28  VAL A CG2 1 
ATOM   120   N N   . LYS A 1 29  ? 148.618 144.781 157.407 1.00 40.12  ? 29  LYS A N   1 
ATOM   121   C CA  . LYS A 1 29  ? 147.318 145.421 157.267 1.00 40.12  ? 29  LYS A CA  1 
ATOM   122   C C   . LYS A 1 29  ? 146.217 144.400 157.514 1.00 40.12  ? 29  LYS A C   1 
ATOM   123   O O   . LYS A 1 29  ? 146.256 143.294 156.967 1.00 40.12  ? 29  LYS A O   1 
ATOM   124   C CB  . LYS A 1 29  ? 147.162 146.045 155.879 1.00 40.12  ? 29  LYS A CB  1 
ATOM   125   C CG  . LYS A 1 29  ? 145.901 146.873 155.709 1.00 40.12  ? 29  LYS A CG  1 
ATOM   126   C CD  . LYS A 1 29  ? 145.854 147.525 154.342 1.00 40.12  ? 29  LYS A CD  1 
ATOM   127   C CE  . LYS A 1 29  ? 145.516 146.513 153.265 1.00 40.12  ? 29  LYS A CE  1 
ATOM   128   N NZ  . LYS A 1 29  ? 145.301 147.165 151.945 1.00 40.12  ? 29  LYS A NZ  1 
ATOM   129   N N   . THR A 1 30  ? 145.240 144.775 158.333 1.00 39.81  ? 30  THR A N   1 
ATOM   130   C CA  . THR A 1 30  ? 144.113 143.919 158.677 1.00 39.81  ? 30  THR A CA  1 
ATOM   131   C C   . THR A 1 30  ? 142.813 144.575 158.211 1.00 39.81  ? 30  THR A C   1 
ATOM   132   O O   . THR A 1 30  ? 142.817 145.594 157.516 1.00 39.81  ? 30  THR A O   1 
ATOM   133   C CB  . THR A 1 30  ? 144.085 143.632 160.181 1.00 39.81  ? 30  THR A CB  1 
ATOM   134   O OG1 . THR A 1 30  ? 143.693 144.812 160.889 1.00 39.81  ? 30  THR A OG1 1 
ATOM   135   C CG2 . THR A 1 30  ? 145.454 143.187 160.669 1.00 39.81  ? 30  THR A CG2 1 
ATOM   136   N N   . ILE A 1 31  ? 141.690 143.968 158.597 1.00 39.91  ? 31  ILE A N   1 
ATOM   137   C CA  . ILE A 1 31  ? 140.384 144.504 158.228 1.00 39.91  ? 31  ILE A CA  1 
ATOM   138   C C   . ILE A 1 31  ? 140.112 145.814 158.961 1.00 39.91  ? 31  ILE A C   1 
ATOM   139   O O   . ILE A 1 31  ? 139.540 146.752 158.393 1.00 39.91  ? 31  ILE A O   1 
ATOM   140   C CB  . ILE A 1 31  ? 139.288 143.457 158.501 1.00 39.91  ? 31  ILE A CB  1 
ATOM   141   C CG1 . ILE A 1 31  ? 139.345 142.337 157.462 1.00 39.91  ? 31  ILE A CG1 1 
ATOM   142   C CG2 . ILE A 1 31  ? 137.910 144.098 158.509 1.00 39.91  ? 31  ILE A CG2 1 
ATOM   143   C CD1 . ILE A 1 31  ? 139.169 142.811 156.040 1.00 39.91  ? 31  ILE A CD1 1 
ATOM   144   N N   . THR A 1 32  ? 140.525 145.906 160.226 1.00 44.28  ? 32  THR A N   1 
ATOM   145   C CA  . THR A 1 32  ? 140.180 147.046 161.065 1.00 44.28  ? 32  THR A CA  1 
ATOM   146   C C   . THR A 1 32  ? 141.331 148.014 161.304 1.00 44.28  ? 32  THR A C   1 
ATOM   147   O O   . THR A 1 32  ? 141.101 149.090 161.864 1.00 44.28  ? 32  THR A O   1 
ATOM   148   C CB  . THR A 1 32  ? 139.659 146.565 162.426 1.00 44.28  ? 32  THR A CB  1 
ATOM   149   O OG1 . THR A 1 32  ? 140.591 145.637 162.994 1.00 44.28  ? 32  THR A OG1 1 
ATOM   150   C CG2 . THR A 1 32  ? 138.308 145.883 162.271 1.00 44.28  ? 32  THR A CG2 1 
ATOM   151   N N   . ASP A 1 33  ? 142.554 147.669 160.906 1.00 45.66  ? 33  ASP A N   1 
ATOM   152   C CA  . ASP A 1 33  ? 143.720 148.512 161.136 1.00 45.66  ? 33  ASP A CA  1 
ATOM   153   C C   . ASP A 1 33  ? 144.441 148.774 159.823 1.00 45.66  ? 33  ASP A C   1 
ATOM   154   O O   . ASP A 1 33  ? 144.697 147.843 159.053 1.00 45.66  ? 33  ASP A O   1 
ATOM   155   C CB  . ASP A 1 33  ? 144.681 147.866 162.139 1.00 45.66  ? 33  ASP A CB  1 
ATOM   156   C CG  . ASP A 1 33  ? 144.115 147.819 163.543 1.00 45.66  ? 33  ASP A CG  1 
ATOM   157   O OD1 . ASP A 1 33  ? 143.308 148.706 163.890 1.00 45.66  ? 33  ASP A OD1 1 
ATOM   158   O OD2 . ASP A 1 33  ? 144.479 146.896 164.301 1.00 45.66  ? 33  ASP A OD2 1 
ATOM   159   N N   . ASP A 1 34  ? 144.764 150.045 159.570 1.00 47.63  ? 34  ASP A N   1 
ATOM   160   C CA  . ASP A 1 34  ? 145.587 150.380 158.413 1.00 47.63  ? 34  ASP A CA  1 
ATOM   161   C C   . ASP A 1 34  ? 147.008 149.859 158.581 1.00 47.63  ? 34  ASP A C   1 
ATOM   162   O O   . ASP A 1 34  ? 147.573 149.266 157.655 1.00 47.63  ? 34  ASP A O   1 
ATOM   163   C CB  . ASP A 1 34  ? 145.599 151.893 158.196 1.00 47.63  ? 34  ASP A CB  1 
ATOM   164   C CG  . ASP A 1 34  ? 144.259 152.431 157.742 1.00 47.63  ? 34  ASP A CG  1 
ATOM   165   O OD1 . ASP A 1 34  ? 143.510 151.684 157.080 1.00 47.63  ? 34  ASP A OD1 1 
ATOM   166   O OD2 . ASP A 1 34  ? 143.953 153.602 158.048 1.00 47.63  ? 34  ASP A OD2 1 
ATOM   167   N N   . GLN A 1 35  ? 147.601 150.076 159.753 1.00 47.65  ? 35  GLN A N   1 
ATOM   168   C CA  . GLN A 1 35  ? 148.957 149.628 160.049 1.00 47.65  ? 35  GLN A CA  1 
ATOM   169   C C   . GLN A 1 35  ? 148.981 149.056 161.456 1.00 47.65  ? 35  GLN A C   1 
ATOM   170   O O   . GLN A 1 35  ? 148.567 149.727 162.405 1.00 47.65  ? 35  GLN A O   1 
ATOM   171   C CB  . GLN A 1 35  ? 149.967 150.775 159.927 1.00 47.65  ? 35  GLN A CB  1 
ATOM   172   C CG  . GLN A 1 35  ? 149.895 151.555 158.626 1.00 47.65  ? 35  GLN A CG  1 
ATOM   173   C CD  . GLN A 1 35  ? 151.259 152.008 158.143 1.00 47.65  ? 35  GLN A CD  1 
ATOM   174   O OE1 . GLN A 1 35  ? 152.179 152.201 158.936 1.00 47.65  ? 35  GLN A OE1 1 
ATOM   175   N NE2 . GLN A 1 35  ? 151.395 152.178 156.834 1.00 47.65  ? 35  GLN A NE2 1 
ATOM   176   N N   . ILE A 1 36  ? 149.459 147.822 161.589 1.00 44.99  ? 36  ILE A N   1 
ATOM   177   C CA  . ILE A 1 36  ? 149.656 147.190 162.887 1.00 44.99  ? 36  ILE A CA  1 
ATOM   178   C C   . ILE A 1 36  ? 150.979 146.437 162.856 1.00 44.99  ? 36  ILE A C   1 
ATOM   179   O O   . ILE A 1 36  ? 151.338 145.830 161.842 1.00 44.99  ? 36  ILE A O   1 
ATOM   180   C CB  . ILE A 1 36  ? 148.476 146.264 163.263 1.00 44.99  ? 36  ILE A CB  1 
ATOM   181   C CG1 . ILE A 1 36  ? 148.585 145.819 164.722 1.00 44.99  ? 36  ILE A CG1 1 
ATOM   182   C CG2 . ILE A 1 36  ? 148.382 145.072 162.327 1.00 44.99  ? 36  ILE A CG2 1 
ATOM   183   C CD1 . ILE A 1 36  ? 147.327 145.185 165.258 1.00 44.99  ? 36  ILE A CD1 1 
ATOM   184   N N   . GLU A 1 37  ? 151.716 146.503 163.960 1.00 46.98  ? 37  GLU A N   1 
ATOM   185   C CA  . GLU A 1 37  ? 153.051 145.927 164.048 1.00 46.98  ? 37  GLU A CA  1 
ATOM   186   C C   . GLU A 1 37  ? 152.977 144.547 164.687 1.00 46.98  ? 37  GLU A C   1 
ATOM   187   O O   . GLU A 1 37  ? 152.355 144.377 165.740 1.00 46.98  ? 37  GLU A O   1 
ATOM   188   C CB  . GLU A 1 37  ? 153.978 146.838 164.853 1.00 46.98  ? 37  GLU A CB  1 
ATOM   189   C CG  . GLU A 1 37  ? 155.423 146.378 164.901 1.00 46.98  ? 37  GLU A CG  1 
ATOM   190   C CD  . GLU A 1 37  ? 156.291 147.288 165.744 1.00 46.98  ? 37  GLU A CD  1 
ATOM   191   O OE1 . GLU A 1 37  ? 155.756 148.263 166.310 1.00 46.98  ? 37  GLU A OE1 1 
ATOM   192   O OE2 . GLU A 1 37  ? 157.509 147.031 165.840 1.00 46.98  ? 37  GLU A OE2 1 
ATOM   193   N N   . VAL A 1 38  ? 153.615 143.567 164.047 1.00 44.71  ? 38  VAL A N   1 
ATOM   194   C CA  . VAL A 1 38  ? 153.620 142.188 164.511 1.00 44.71  ? 38  VAL A CA  1 
ATOM   195   C C   . VAL A 1 38  ? 155.065 141.720 164.638 1.00 44.71  ? 38  VAL A C   1 
ATOM   196   O O   . VAL A 1 38  ? 155.994 142.350 164.133 1.00 44.71  ? 38  VAL A O   1 
ATOM   197   C CB  . VAL A 1 38  ? 152.824 141.251 163.578 1.00 44.71  ? 38  VAL A CB  1 
ATOM   198   C CG1 . VAL A 1 38  ? 151.343 141.575 163.644 1.00 44.71  ? 38  VAL A CG1 1 
ATOM   199   C CG2 . VAL A 1 38  ? 153.333 141.366 162.153 1.00 44.71  ? 38  VAL A CG2 1 
ATOM   200   N N   . THR A 1 39  ? 155.243 140.594 165.330 1.00 46.41  ? 39  THR A N   1 
ATOM   201   C CA  . THR A 1 39  ? 156.578 140.067 165.583 1.00 46.41  ? 39  THR A CA  1 
ATOM   202   C C   . THR A 1 39  ? 157.192 139.380 164.370 1.00 46.41  ? 39  THR A C   1 
ATOM   203   O O   . THR A 1 39  ? 158.418 139.245 164.310 1.00 46.41  ? 39  THR A O   1 
ATOM   204   C CB  . THR A 1 39  ? 156.547 139.084 166.756 1.00 46.41  ? 39  THR A CB  1 
ATOM   205   O OG1 . THR A 1 39  ? 155.647 138.010 166.459 1.00 46.41  ? 39  THR A OG1 1 
ATOM   206   C CG2 . THR A 1 39  ? 156.092 139.779 168.026 1.00 46.41  ? 39  THR A CG2 1 
ATOM   207   N N   . ASN A 1 40  ? 156.381 138.945 163.409 1.00 44.20  ? 40  ASN A N   1 
ATOM   208   C CA  . ASN A 1 40  ? 156.893 138.192 162.273 1.00 44.20  ? 40  ASN A CA  1 
ATOM   209   C C   . ASN A 1 40  ? 155.909 138.299 161.117 1.00 44.20  ? 40  ASN A C   1 
ATOM   210   O O   . ASN A 1 40  ? 154.697 138.392 161.325 1.00 44.20  ? 40  ASN A O   1 
ATOM   211   C CB  . ASN A 1 40  ? 157.127 136.725 162.650 1.00 44.20  ? 40  ASN A CB  1 
ATOM   212   C CG  . ASN A 1 40  ? 158.106 136.029 161.727 1.00 44.20  ? 40  ASN A CG  1 
ATOM   213   O OD1 . ASN A 1 40  ? 158.931 136.667 161.074 1.00 44.20  ? 40  ASN A OD1 1 
ATOM   214   N ND2 . ASN A 1 40  ? 158.018 134.705 161.674 1.00 44.20  ? 40  ASN A ND2 1 
ATOM   215   N N   . ALA A 1 41  ? 156.447 138.281 159.899 1.00 38.55  ? 41  ALA A N   1 
ATOM   216   C CA  . ALA A 1 41  ? 155.633 138.346 158.694 1.00 38.55  ? 41  ALA A CA  1 
ATOM   217   C C   . ALA A 1 41  ? 156.401 137.725 157.538 1.00 38.55  ? 41  ALA A C   1 
ATOM   218   O O   . ALA A 1 41  ? 157.626 137.584 157.585 1.00 38.55  ? 41  ALA A O   1 
ATOM   219   C CB  . ALA A 1 41  ? 155.232 139.786 158.357 1.00 38.55  ? 41  ALA A CB  1 
ATOM   220   N N   . THR A 1 42  ? 155.664 137.353 156.492 1.00 34.79  ? 42  THR A N   1 
ATOM   221   C CA  . THR A 1 42  ? 156.242 136.755 155.297 1.00 34.79  ? 42  THR A CA  1 
ATOM   222   C C   . THR A 1 42  ? 155.696 137.444 154.055 1.00 34.79  ? 42  THR A C   1 
ATOM   223   O O   . THR A 1 42  ? 154.585 137.980 154.059 1.00 34.79  ? 42  THR A O   1 
ATOM   224   C CB  . THR A 1 42  ? 155.951 135.248 155.210 1.00 34.79  ? 42  THR A CB  1 
ATOM   225   O OG1 . THR A 1 42  ? 154.537 135.033 155.144 1.00 34.79  ? 42  THR A OG1 1 
ATOM   226   C CG2 . THR A 1 42  ? 156.517 134.517 156.416 1.00 34.79  ? 42  THR A CG2 1 
ATOM   227   N N   . GLU A 1 43  ? 156.493 137.424 152.990 1.00 30.35  ? 43  GLU A N   1 
ATOM   228   C CA  . GLU A 1 43  ? 156.101 138.001 151.713 1.00 30.35  ? 43  GLU A CA  1 
ATOM   229   C C   . GLU A 1 43  ? 155.355 136.969 150.877 1.00 30.35  ? 43  GLU A C   1 
ATOM   230   O O   . GLU A 1 43  ? 155.750 135.802 150.811 1.00 30.35  ? 43  GLU A O   1 
ATOM   231   C CB  . GLU A 1 43  ? 157.329 138.507 150.954 1.00 30.35  ? 43  GLU A CB  1 
ATOM   232   C CG  . GLU A 1 43  ? 157.015 139.130 149.607 1.00 30.35  ? 43  GLU A CG  1 
ATOM   233   C CD  . GLU A 1 43  ? 156.267 140.440 149.733 1.00 30.35  ? 43  GLU A CD  1 
ATOM   234   O OE1 . GLU A 1 43  ? 156.763 141.345 150.435 1.00 30.35  ? 43  GLU A OE1 1 
ATOM   235   O OE2 . GLU A 1 43  ? 155.181 140.564 149.132 1.00 30.35  ? 43  GLU A OE2 1 
ATOM   236   N N   . LEU A 1 44  ? 154.270 137.407 150.240 1.00 28.08  ? 44  LEU A N   1 
ATOM   237   C CA  . LEU A 1 44  ? 153.406 136.521 149.474 1.00 28.08  ? 44  LEU A CA  1 
ATOM   238   C C   . LEU A 1 44  ? 153.484 136.741 147.969 1.00 28.08  ? 44  LEU A C   1 
ATOM   239   O O   . LEU A 1 44  ? 152.834 136.005 147.221 1.00 28.08  ? 44  LEU A O   1 
ATOM   240   C CB  . LEU A 1 44  ? 151.951 136.677 149.932 1.00 28.08  ? 44  LEU A CB  1 
ATOM   241   C CG  . LEU A 1 44  ? 151.570 136.103 151.298 1.00 28.08  ? 44  LEU A CG  1 
ATOM   242   C CD1 . LEU A 1 44  ? 150.063 135.966 151.409 1.00 28.08  ? 44  LEU A CD1 1 
ATOM   243   C CD2 . LEU A 1 44  ? 152.250 134.765 151.537 1.00 28.08  ? 44  LEU A CD2 1 
ATOM   244   N N   . VAL A 1 45  ? 154.253 137.721 147.502 1.00 26.43  ? 45  VAL A N   1 
ATOM   245   C CA  . VAL A 1 45  ? 154.320 138.063 146.085 1.00 26.43  ? 45  VAL A CA  1 
ATOM   246   C C   . VAL A 1 45  ? 155.759 137.920 145.609 1.00 26.43  ? 45  VAL A C   1 
ATOM   247   O O   . VAL A 1 45  ? 156.676 138.498 146.203 1.00 26.43  ? 45  VAL A O   1 
ATOM   248   C CB  . VAL A 1 45  ? 153.799 139.487 145.818 1.00 26.43  ? 45  VAL A CB  1 
ATOM   249   C CG1 . VAL A 1 45  ? 153.896 139.818 144.341 1.00 26.43  ? 45  VAL A CG1 1 
ATOM   250   C CG2 . VAL A 1 45  ? 152.369 139.627 146.302 1.00 26.43  ? 45  VAL A CG2 1 
ATOM   251   N N   . GLN A 1 46  ? 155.949 137.154 144.538 1.00 26.85  ? 46  GLN A N   1 
ATOM   252   C CA  . GLN A 1 46  ? 157.248 137.011 143.894 1.00 26.85  ? 46  GLN A CA  1 
ATOM   253   C C   . GLN A 1 46  ? 157.380 138.087 142.822 1.00 26.85  ? 46  GLN A C   1 
ATOM   254   O O   . GLN A 1 46  ? 156.539 138.177 141.922 1.00 26.85  ? 46  GLN A O   1 
ATOM   255   C CB  . GLN A 1 46  ? 157.393 135.616 143.288 1.00 26.85  ? 46  GLN A CB  1 
ATOM   256   C CG  . GLN A 1 46  ? 158.636 135.424 142.442 1.00 26.85  ? 46  GLN A CG  1 
ATOM   257   C CD  . GLN A 1 46  ? 159.863 135.133 143.276 1.00 26.85  ? 46  GLN A CD  1 
ATOM   258   O OE1 . GLN A 1 46  ? 159.812 134.350 144.222 1.00 26.85  ? 46  GLN A OE1 1 
ATOM   259   N NE2 . GLN A 1 46  ? 160.976 135.764 142.928 1.00 26.85  ? 46  GLN A NE2 1 
ATOM   260   N N   . ASN A 1 47  ? 158.434 138.902 142.915 1.00 27.76  ? 47  ASN A N   1 
ATOM   261   C CA  . ASN A 1 47  ? 158.576 140.059 142.038 1.00 27.76  ? 47  ASN A CA  1 
ATOM   262   C C   . ASN A 1 47  ? 159.969 140.171 141.428 1.00 27.76  ? 47  ASN A C   1 
ATOM   263   O O   . ASN A 1 47  ? 160.386 141.273 141.057 1.00 27.76  ? 47  ASN A O   1 
ATOM   264   C CB  . ASN A 1 47  ? 158.227 141.346 142.790 1.00 27.76  ? 47  ASN A CB  1 
ATOM   265   C CG  . ASN A 1 47  ? 159.173 141.625 143.943 1.00 27.76  ? 47  ASN A CG  1 
ATOM   266   O OD1 . ASN A 1 47  ? 159.950 140.762 144.348 1.00 27.76  ? 47  ASN A OD1 1 
ATOM   267   N ND2 . ASN A 1 47  ? 159.107 142.836 144.480 1.00 27.76  ? 47  ASN A ND2 1 
ATOM   268   N N   . SER A 1 48  ? 160.699 139.065 141.308 1.00 28.30  ? 48  SER A N   1 
ATOM   269   C CA  . SER A 1 48  ? 162.031 139.112 140.726 1.00 28.30  ? 48  SER A CA  1 
ATOM   270   C C   . SER A 1 48  ? 162.315 137.804 140.004 1.00 28.30  ? 48  SER A C   1 
ATOM   271   O O   . SER A 1 48  ? 161.673 136.780 140.251 1.00 28.30  ? 48  SER A O   1 
ATOM   272   C CB  . SER A 1 48  ? 163.104 139.383 141.788 1.00 28.30  ? 48  SER A CB  1 
ATOM   273   O OG  . SER A 1 48  ? 163.161 138.336 142.741 1.00 28.30  ? 48  SER A OG  1 
ATOM   274   N N   . SER A 1 49  ? 163.291 137.856 139.101 1.00 29.85  ? 49  SER A N   1 
ATOM   275   C CA  . SER A 1 49  ? 163.715 136.696 138.334 1.00 29.85  ? 49  SER A CA  1 
ATOM   276   C C   . SER A 1 49  ? 165.216 136.779 138.098 1.00 29.85  ? 49  SER A C   1 
ATOM   277   O O   . SER A 1 49  ? 165.817 137.854 138.166 1.00 29.85  ? 49  SER A O   1 
ATOM   278   C CB  . SER A 1 49  ? 162.970 136.598 136.997 1.00 29.85  ? 49  SER A CB  1 
ATOM   279   O OG  . SER A 1 49  ? 163.500 135.558 136.196 1.00 29.85  ? 49  SER A OG  1 
ATOM   280   N N   . THR A 1 50  ? 165.819 135.624 137.820 1.00 33.23  ? 50  THR A N   1 
ATOM   281   C CA  . THR A 1 50  ? 167.250 135.559 137.556 1.00 33.23  ? 50  THR A CA  1 
ATOM   282   C C   . THR A 1 50  ? 167.611 135.916 136.120 1.00 33.23  ? 50  THR A C   1 
ATOM   283   O O   . THR A 1 50  ? 168.791 136.147 135.837 1.00 33.23  ? 50  THR A O   1 
ATOM   284   C CB  . THR A 1 50  ? 167.785 134.161 137.877 1.00 33.23  ? 50  THR A CB  1 
ATOM   285   O OG1 . THR A 1 50  ? 167.138 133.195 137.041 1.00 33.23  ? 50  THR A OG1 1 
ATOM   286   C CG2 . THR A 1 50  ? 167.533 133.817 139.335 1.00 33.23  ? 50  THR A CG2 1 
ATOM   287   N N   . GLY A 1 51  ? 166.637 135.969 135.214 1.00 32.62  ? 51  GLY A N   1 
ATOM   288   C CA  . GLY A 1 51  ? 166.905 136.307 133.833 1.00 32.62  ? 51  GLY A CA  1 
ATOM   289   C C   . GLY A 1 51  ? 167.294 135.150 132.943 1.00 32.62  ? 51  GLY A C   1 
ATOM   290   O O   . GLY A 1 51  ? 167.545 135.365 131.753 1.00 32.62  ? 51  GLY A O   1 
ATOM   291   N N   . LYS A 1 52  ? 167.353 133.932 133.474 1.00 33.16  ? 52  LYS A N   1 
ATOM   292   C CA  . LYS A 1 52  ? 167.684 132.748 132.698 1.00 33.16  ? 52  LYS A CA  1 
ATOM   293   C C   . LYS A 1 52  ? 166.504 131.787 132.702 1.00 33.16  ? 52  LYS A C   1 
ATOM   294   O O   . LYS A 1 52  ? 165.657 131.823 133.600 1.00 33.16  ? 52  LYS A O   1 
ATOM   295   C CB  . LYS A 1 52  ? 168.925 132.040 133.253 1.00 33.16  ? 52  LYS A CB  1 
ATOM   296   C CG  . LYS A 1 52  ? 170.036 132.973 133.698 1.00 33.16  ? 52  LYS A CG  1 
ATOM   297   C CD  . LYS A 1 52  ? 170.658 133.696 132.521 1.00 33.16  ? 52  LYS A CD  1 
ATOM   298   C CE  . LYS A 1 52  ? 171.690 134.710 132.982 1.00 33.16  ? 52  LYS A CE  1 
ATOM   299   N NZ  . LYS A 1 52  ? 172.883 134.050 133.577 1.00 33.16  ? 52  LYS A NZ  1 
ATOM   300   N N   . ILE A 1 53  ? 166.455 130.925 131.691 1.00 31.00  ? 53  ILE A N   1 
ATOM   301   C CA  . ILE A 1 53  ? 165.405 129.924 131.549 1.00 31.00  ? 53  ILE A CA  1 
ATOM   302   C C   . ILE A 1 53  ? 166.018 128.556 131.813 1.00 31.00  ? 53  ILE A C   1 
ATOM   303   O O   . ILE A 1 53  ? 166.989 128.166 131.153 1.00 31.00  ? 53  ILE A O   1 
ATOM   304   C CB  . ILE A 1 53  ? 164.753 129.976 130.159 1.00 31.00  ? 53  ILE A CB  1 
ATOM   305   C CG1 . ILE A 1 53  ? 163.958 131.271 129.988 1.00 31.00  ? 53  ILE A CG1 1 
ATOM   306   C CG2 . ILE A 1 53  ? 163.854 128.770 129.943 1.00 31.00  ? 53  ILE A CG2 1 
ATOM   307   C CD1 . ILE A 1 53  ? 163.409 131.468 128.594 1.00 31.00  ? 53  ILE A CD1 1 
ATOM   308   N N   . CYS A 1 54  ? 165.459 127.834 132.780 1.00 34.73  ? 54  CYS A N   1 
ATOM   309   C CA  . CYS A 1 54  ? 165.924 126.485 133.073 1.00 34.73  ? 54  CYS A CA  1 
ATOM   310   C C   . CYS A 1 54  ? 165.497 125.521 131.973 1.00 34.73  ? 54  CYS A C   1 
ATOM   311   O O   . CYS A 1 54  ? 164.395 125.624 131.428 1.00 34.73  ? 54  CYS A O   1 
ATOM   312   C CB  . CYS A 1 54  ? 165.382 126.014 134.422 1.00 34.73  ? 54  CYS A CB  1 
ATOM   313   S SG  . CYS A 1 54  ? 166.129 126.812 135.859 1.00 34.73  ? 54  CYS A SG  1 
ATOM   314   N N   . ASN A 1 55  ? 166.376 124.575 131.652 1.00 35.23  ? 55  ASN A N   1 
ATOM   315   C CA  . ASN A 1 55  ? 166.081 123.562 130.649 1.00 35.23  ? 55  ASN A CA  1 
ATOM   316   C C   . ASN A 1 55  ? 165.478 122.295 131.242 1.00 35.23  ? 55  ASN A C   1 
ATOM   317   O O   . ASN A 1 55  ? 165.273 121.322 130.509 1.00 35.23  ? 55  ASN A O   1 
ATOM   318   C CB  . ASN A 1 55  ? 167.344 123.219 129.846 1.00 35.23  ? 55  ASN A CB  1 
ATOM   319   C CG  . ASN A 1 55  ? 168.462 122.652 130.706 1.00 35.23  ? 55  ASN A CG  1 
ATOM   320   O OD1 . ASN A 1 55  ? 168.261 122.288 131.863 1.00 35.23  ? 55  ASN A OD1 1 
ATOM   321   N ND2 . ASN A 1 55  ? 169.655 122.570 130.130 1.00 35.23  ? 55  ASN A ND2 1 
ATOM   322   N N   . ASN A 1 56  ? 165.204 122.279 132.542 1.00 33.93  ? 56  ASN A N   1 
ATOM   323   C CA  . ASN A 1 56  ? 164.569 121.162 133.219 1.00 33.93  ? 56  ASN A CA  1 
ATOM   324   C C   . ASN A 1 56  ? 163.434 121.678 134.090 1.00 33.93  ? 56  ASN A C   1 
ATOM   325   O O   . ASN A 1 56  ? 163.510 122.793 134.615 1.00 33.93  ? 56  ASN A O   1 
ATOM   326   C CB  . ASN A 1 56  ? 165.577 120.395 134.087 1.00 33.93  ? 56  ASN A CB  1 
ATOM   327   C CG  . ASN A 1 56  ? 166.347 119.355 133.301 1.00 33.93  ? 56  ASN A CG  1 
ATOM   328   O OD1 . ASN A 1 56  ? 165.761 118.479 132.667 1.00 33.93  ? 56  ASN A OD1 1 
ATOM   329   N ND2 . ASN A 1 56  ? 167.671 119.444 133.343 1.00 33.93  ? 56  ASN A ND2 1 
ATOM   330   N N   . PRO A 1 57  ? 162.363 120.886 134.268 1.00 32.26  ? 57  PRO A N   1 
ATOM   331   C CA  . PRO A 1 57  ? 162.151 119.556 133.689 1.00 32.26  ? 57  PRO A CA  1 
ATOM   332   C C   . PRO A 1 57  ? 161.508 119.585 132.303 1.00 32.26  ? 57  PRO A C   1 
ATOM   333   O O   . PRO A 1 57  ? 161.458 118.554 131.635 1.00 32.26  ? 57  PRO A O   1 
ATOM   334   C CB  . PRO A 1 57  ? 161.215 118.898 134.698 1.00 32.26  ? 57  PRO A CB  1 
ATOM   335   C CG  . PRO A 1 57  ? 160.389 120.031 135.200 1.00 32.26  ? 57  PRO A CG  1 
ATOM   336   C CD  . PRO A 1 57  ? 161.267 121.260 135.179 1.00 32.26  ? 57  PRO A CD  1 
ATOM   337   N N   . HIS A 1 58  ? 161.024 120.750 131.883 1.00 31.08  ? 58  HIS A N   1 
ATOM   338   C CA  . HIS A 1 58  ? 160.410 120.873 130.570 1.00 31.08  ? 58  HIS A CA  1 
ATOM   339   C C   . HIS A 1 58  ? 161.470 120.823 129.476 1.00 31.08  ? 58  HIS A C   1 
ATOM   340   O O   . HIS A 1 58  ? 162.634 121.166 129.691 1.00 31.08  ? 58  HIS A O   1 
ATOM   341   C CB  . HIS A 1 58  ? 159.624 122.180 130.464 1.00 31.08  ? 58  HIS A CB  1 
ATOM   342   C CG  . HIS A 1 58  ? 158.731 122.450 131.633 1.00 31.08  ? 58  HIS A CG  1 
ATOM   343   N ND1 . HIS A 1 58  ? 157.595 121.713 131.889 1.00 31.08  ? 58  HIS A ND1 1 
ATOM   344   C CD2 . HIS A 1 58  ? 158.800 123.384 132.610 1.00 31.08  ? 58  HIS A CD2 1 
ATOM   345   C CE1 . HIS A 1 58  ? 157.006 122.179 132.975 1.00 31.08  ? 58  HIS A CE1 1 
ATOM   346   N NE2 . HIS A 1 58  ? 157.717 123.193 133.432 1.00 31.08  ? 58  HIS A NE2 1 
ATOM   347   N N   . LYS A 1 59  ? 161.053 120.396 128.288 1.00 28.19  ? 59  LYS A N   1 
ATOM   348   C CA  . LYS A 1 59  ? 161.928 120.367 127.122 1.00 28.19  ? 59  LYS A CA  1 
ATOM   349   C C   . LYS A 1 59  ? 161.756 121.674 126.358 1.00 28.19  ? 59  LYS A C   1 
ATOM   350   O O   . LYS A 1 59  ? 160.720 121.900 125.725 1.00 28.19  ? 59  LYS A O   1 
ATOM   351   C CB  . LYS A 1 59  ? 161.617 119.167 126.234 1.00 28.19  ? 59  LYS A CB  1 
ATOM   352   C CG  . LYS A 1 59  ? 162.600 118.984 125.092 1.00 28.19  ? 59  LYS A CG  1 
ATOM   353   C CD  . LYS A 1 59  ? 162.169 117.872 124.157 1.00 28.19  ? 59  LYS A CD  1 
ATOM   354   C CE  . LYS A 1 59  ? 163.281 117.512 123.188 1.00 28.19  ? 59  LYS A CE  1 
ATOM   355   N NZ  . LYS A 1 59  ? 163.688 118.678 122.355 1.00 28.19  ? 59  LYS A NZ  1 
ATOM   356   N N   . VAL A 1 60  ? 162.770 122.531 126.413 1.00 27.89  ? 60  VAL A N   1 
ATOM   357   C CA  . VAL A 1 60  ? 162.729 123.847 125.789 1.00 27.89  ? 60  VAL A CA  1 
ATOM   358   C C   . VAL A 1 60  ? 163.548 123.804 124.508 1.00 27.89  ? 60  VAL A C   1 
ATOM   359   O O   . VAL A 1 60  ? 164.722 123.412 124.525 1.00 27.89  ? 60  VAL A O   1 
ATOM   360   C CB  . VAL A 1 60  ? 163.255 124.931 126.744 1.00 27.89  ? 60  VAL A CB  1 
ATOM   361   C CG1 . VAL A 1 60  ? 163.227 126.287 126.070 1.00 27.89  ? 60  VAL A CG1 1 
ATOM   362   C CG2 . VAL A 1 60  ? 162.437 124.950 128.023 1.00 27.89  ? 60  VAL A CG2 1 
ATOM   363   N N   . LEU A 1 61  ? 162.934 124.205 123.399 1.00 26.56  ? 61  LEU A N   1 
ATOM   364   C CA  . LEU A 1 61  ? 163.592 124.244 122.100 1.00 26.56  ? 61  LEU A CA  1 
ATOM   365   C C   . LEU A 1 61  ? 163.826 125.697 121.712 1.00 26.56  ? 61  LEU A C   1 
ATOM   366   O O   . LEU A 1 61  ? 162.874 126.476 121.605 1.00 26.56  ? 61  LEU A O   1 
ATOM   367   C CB  . LEU A 1 61  ? 162.756 123.530 121.038 1.00 26.56  ? 61  LEU A CB  1 
ATOM   368   C CG  . LEU A 1 61  ? 163.370 123.440 119.640 1.00 26.56  ? 61  LEU A CG  1 
ATOM   369   C CD1 . LEU A 1 61  ? 164.689 122.691 119.681 1.00 26.56  ? 61  LEU A CD1 1 
ATOM   370   C CD2 . LEU A 1 61  ? 162.405 122.775 118.678 1.00 26.56  ? 61  LEU A CD2 1 
ATOM   371   N N   . ASP A 1 62  ? 165.089 126.053 121.500 1.00 28.75  ? 62  ASP A N   1 
ATOM   372   C CA  . ASP A 1 62  ? 165.472 127.415 121.151 1.00 28.75  ? 62  ASP A CA  1 
ATOM   373   C C   . ASP A 1 62  ? 165.525 127.541 119.632 1.00 28.75  ? 62  ASP A C   1 
ATOM   374   O O   . ASP A 1 62  ? 166.346 126.891 118.977 1.00 28.75  ? 62  ASP A O   1 
ATOM   375   C CB  . ASP A 1 62  ? 166.818 127.766 121.780 1.00 28.75  ? 62  ASP A CB  1 
ATOM   376   C CG  . ASP A 1 62  ? 167.245 129.190 121.493 1.00 28.75  ? 62  ASP A CG  1 
ATOM   377   O OD1 . ASP A 1 62  ? 166.369 130.032 121.209 1.00 28.75  ? 62  ASP A OD1 1 
ATOM   378   O OD2 . ASP A 1 62  ? 168.460 129.467 121.551 1.00 28.75  ? 62  ASP A OD2 1 
ATOM   379   N N   . GLY A 1 63  ? 164.643 128.366 119.073 1.00 28.31  ? 63  GLY A N   1 
ATOM   380   C CA  . GLY A 1 63  ? 164.721 128.708 117.667 1.00 28.31  ? 63  GLY A CA  1 
ATOM   381   C C   . GLY A 1 63  ? 165.503 129.989 117.470 1.00 28.31  ? 63  GLY A C   1 
ATOM   382   O O   . GLY A 1 63  ? 164.956 131.084 117.625 1.00 28.31  ? 63  GLY A O   1 
ATOM   383   N N   . ARG A 1 64  ? 166.784 129.863 117.124 1.00 31.47  ? 64  ARG A N   1 
ATOM   384   C CA  . ARG A 1 64  ? 167.702 130.996 117.143 1.00 31.47  ? 64  ARG A CA  1 
ATOM   385   C C   . ARG A 1 64  ? 167.285 132.095 116.175 1.00 31.47  ? 64  ARG A C   1 
ATOM   386   O O   . ARG A 1 64  ? 166.923 133.198 116.596 1.00 31.47  ? 64  ARG A O   1 
ATOM   387   C CB  . ARG A 1 64  ? 169.126 130.538 116.812 1.00 31.47  ? 64  ARG A CB  1 
ATOM   388   C CG  . ARG A 1 64  ? 169.872 129.882 117.964 1.00 31.47  ? 64  ARG A CG  1 
ATOM   389   C CD  . ARG A 1 64  ? 169.387 128.470 118.235 1.00 31.47  ? 64  ARG A CD  1 
ATOM   390   N NE  . ARG A 1 64  ? 170.146 127.838 119.306 1.00 31.47  ? 64  ARG A NE  1 
ATOM   391   C CZ  . ARG A 1 64  ? 171.273 127.163 119.129 1.00 31.47  ? 64  ARG A CZ  1 
ATOM   392   N NH1 . ARG A 1 64  ? 171.812 127.019 117.930 1.00 31.47  ? 64  ARG A NH1 1 
ATOM   393   N NH2 . ARG A 1 64  ? 171.877 126.621 120.183 1.00 31.47  ? 64  ARG A NH2 1 
ATOM   394   N N   . ASP A 1 65  ? 167.328 131.803 114.877 1.00 30.81  ? 65  ASP A N   1 
ATOM   395   C CA  . ASP A 1 65  ? 166.999 132.781 113.848 1.00 30.81  ? 65  ASP A CA  1 
ATOM   396   C C   . ASP A 1 65  ? 165.784 132.370 113.031 1.00 30.81  ? 65  ASP A C   1 
ATOM   397   O O   . ASP A 1 65  ? 165.554 132.933 111.955 1.00 30.81  ? 65  ASP A O   1 
ATOM   398   C CB  . ASP A 1 65  ? 168.199 133.003 112.925 1.00 30.81  ? 65  ASP A CB  1 
ATOM   399   C CG  . ASP A 1 65  ? 169.254 133.894 113.546 1.00 30.81  ? 65  ASP A CG  1 
ATOM   400   O OD1 . ASP A 1 65  ? 168.944 134.578 114.543 1.00 30.81  ? 65  ASP A OD1 1 
ATOM   401   O OD2 . ASP A 1 65  ? 170.395 133.908 113.041 1.00 30.81  ? 65  ASP A OD2 1 
ATOM   402   N N   . CYS A 1 66  ? 165.003 131.406 113.510 1.00 28.43  ? 66  CYS A N   1 
ATOM   403   C CA  . CYS A 1 66  ? 163.885 130.849 112.768 1.00 28.43  ? 66  CYS A CA  1 
ATOM   404   C C   . CYS A 1 66  ? 162.603 130.969 113.576 1.00 28.43  ? 66  CYS A C   1 
ATOM   405   O O   . CYS A 1 66  ? 162.610 130.807 114.800 1.00 28.43  ? 66  CYS A O   1 
ATOM   406   C CB  . CYS A 1 66  ? 164.135 129.380 112.424 1.00 28.43  ? 66  CYS A CB  1 
ATOM   407   S SG  . CYS A 1 66  ? 165.470 129.104 111.248 1.00 28.43  ? 66  CYS A SG  1 
ATOM   408   N N   . THR A 1 67  ? 161.508 131.257 112.885 1.00 23.66  ? 67  THR A N   1 
ATOM   409   C CA  . THR A 1 67  ? 160.185 131.163 113.475 1.00 23.66  ? 67  THR A CA  1 
ATOM   410   C C   . THR A 1 67  ? 159.645 129.748 113.293 1.00 23.66  ? 67  THR A C   1 
ATOM   411   O O   . THR A 1 67  ? 160.190 128.939 112.540 1.00 23.66  ? 67  THR A O   1 
ATOM   412   C CB  . THR A 1 67  ? 159.238 132.190 112.854 1.00 23.66  ? 67  THR A CB  1 
ATOM   413   O OG1 . THR A 1 67  ? 159.076 131.914 111.458 1.00 23.66  ? 67  THR A OG1 1 
ATOM   414   C CG2 . THR A 1 67  ? 159.792 133.594 113.023 1.00 23.66  ? 67  THR A CG2 1 
ATOM   415   N N   . LEU A 1 68  ? 158.562 129.445 114.009 1.00 22.07  ? 68  LEU A N   1 
ATOM   416   C CA  . LEU A 1 68  ? 157.985 128.107 113.930 1.00 22.07  ? 68  LEU A CA  1 
ATOM   417   C C   . LEU A 1 68  ? 157.424 127.825 112.541 1.00 22.07  ? 68  LEU A C   1 
ATOM   418   O O   . LEU A 1 68  ? 157.564 126.711 112.024 1.00 22.07  ? 68  LEU A O   1 
ATOM   419   C CB  . LEU A 1 68  ? 156.904 127.940 114.996 1.00 22.07  ? 68  LEU A CB  1 
ATOM   420   C CG  . LEU A 1 68  ? 156.329 126.536 115.175 1.00 22.07  ? 68  LEU A CG  1 
ATOM   421   C CD1 . LEU A 1 68  ? 157.431 125.538 115.476 1.00 22.07  ? 68  LEU A CD1 1 
ATOM   422   C CD2 . LEU A 1 68  ? 155.291 126.533 116.278 1.00 22.07  ? 68  LEU A CD2 1 
ATOM   423   N N   . ILE A 1 69  ? 156.792 128.822 111.919 1.00 21.70  ? 69  ILE A N   1 
ATOM   424   C CA  . ILE A 1 69  ? 156.252 128.638 110.575 1.00 21.70  ? 69  ILE A CA  1 
ATOM   425   C C   . ILE A 1 69  ? 157.378 128.454 109.565 1.00 21.70  ? 69  ILE A C   1 
ATOM   426   O O   . ILE A 1 69  ? 157.279 127.627 108.651 1.00 21.70  ? 69  ILE A O   1 
ATOM   427   C CB  . ILE A 1 69  ? 155.340 129.822 110.202 1.00 21.70  ? 69  ILE A CB  1 
ATOM   428   C CG1 . ILE A 1 69  ? 154.189 129.943 111.203 1.00 21.70  ? 69  ILE A CG1 1 
ATOM   429   C CG2 . ILE A 1 69  ? 154.802 129.662 108.790 1.00 21.70  ? 69  ILE A CG2 1 
ATOM   430   C CD1 . ILE A 1 69  ? 153.168 128.837 111.099 1.00 21.70  ? 69  ILE A CD1 1 
ATOM   431   N N   . ASP A 1 70  ? 158.462 129.220 109.709 1.00 23.79  ? 70  ASP A N   1 
ATOM   432   C CA  . ASP A 1 70  ? 159.596 129.083 108.800 1.00 23.79  ? 70  ASP A CA  1 
ATOM   433   C C   . ASP A 1 70  ? 160.257 127.717 108.937 1.00 23.79  ? 70  ASP A C   1 
ATOM   434   O O   . ASP A 1 70  ? 160.650 127.109 107.936 1.00 23.79  ? 70  ASP A O   1 
ATOM   435   C CB  . ASP A 1 70  ? 160.612 130.194 109.056 1.00 23.79  ? 70  ASP A CB  1 
ATOM   436   C CG  . ASP A 1 70  ? 160.307 131.451 108.272 1.00 23.79  ? 70  ASP A CG  1 
ATOM   437   O OD1 . ASP A 1 70  ? 159.793 131.339 107.141 1.00 23.79  ? 70  ASP A OD1 1 
ATOM   438   O OD2 . ASP A 1 70  ? 160.586 132.553 108.787 1.00 23.79  ? 70  ASP A OD2 1 
ATOM   439   N N   . ALA A 1 71  ? 160.403 127.227 110.170 1.00 24.36  ? 71  ALA A N   1 
ATOM   440   C CA  . ALA A 1 71  ? 160.968 125.898 110.375 1.00 24.36  ? 71  ALA A CA  1 
ATOM   441   C C   . ALA A 1 71  ? 160.041 124.808 109.855 1.00 24.36  ? 71  ALA A C   1 
ATOM   442   O O   . ALA A 1 71  ? 160.514 123.783 109.352 1.00 24.36  ? 71  ALA A O   1 
ATOM   443   C CB  . ALA A 1 71  ? 161.270 125.679 111.857 1.00 24.36  ? 71  ALA A CB  1 
ATOM   444   N N   . MET A 1 72  ? 158.727 125.004 109.978 1.00 23.21  ? 72  MET A N   1 
ATOM   445   C CA  . MET A 1 72  ? 157.775 124.043 109.432 1.00 23.21  ? 72  MET A CA  1 
ATOM   446   C C   . MET A 1 72  ? 157.836 124.000 107.910 1.00 23.21  ? 72  MET A C   1 
ATOM   447   O O   . MET A 1 72  ? 157.788 122.919 107.313 1.00 23.21  ? 72  MET A O   1 
ATOM   448   C CB  . MET A 1 72  ? 156.363 124.390 109.901 1.00 23.21  ? 72  MET A CB  1 
ATOM   449   C CG  . MET A 1 72  ? 155.315 123.350 109.557 1.00 23.21  ? 72  MET A CG  1 
ATOM   450   S SD  . MET A 1 72  ? 153.661 124.058 109.477 1.00 23.21  ? 72  MET A SD  1 
ATOM   451   C CE  . MET A 1 72  ? 153.851 125.215 108.125 1.00 23.21  ? 72  MET A CE  1 
ATOM   452   N N   . LEU A 1 73  ? 157.941 125.165 107.266 1.00 22.12  ? 73  LEU A N   1 
ATOM   453   C CA  . LEU A 1 73  ? 157.911 125.213 105.807 1.00 22.12  ? 73  LEU A CA  1 
ATOM   454   C C   . LEU A 1 73  ? 159.158 124.585 105.196 1.00 22.12  ? 73  LEU A C   1 
ATOM   455   O O   . LEU A 1 73  ? 159.083 123.949 104.139 1.00 22.12  ? 73  LEU A O   1 
ATOM   456   C CB  . LEU A 1 73  ? 157.750 126.656 105.331 1.00 22.12  ? 73  LEU A CB  1 
ATOM   457   C CG  . LEU A 1 73  ? 156.331 127.226 105.375 1.00 22.12  ? 73  LEU A CG  1 
ATOM   458   C CD1 . LEU A 1 73  ? 156.315 128.661 104.882 1.00 22.12  ? 73  LEU A CD1 1 
ATOM   459   C CD2 . LEU A 1 73  ? 155.385 126.368 104.557 1.00 22.12  ? 73  LEU A CD2 1 
ATOM   460   N N   . GLY A 1 74  ? 160.311 124.749 105.839 1.00 24.11  ? 74  GLY A N   1 
ATOM   461   C CA  . GLY A 1 74  ? 161.542 124.211 105.297 1.00 24.11  ? 74  GLY A CA  1 
ATOM   462   C C   . GLY A 1 74  ? 162.491 125.258 104.751 1.00 24.11  ? 74  GLY A C   1 
ATOM   463   O O   . GLY A 1 74  ? 163.101 125.061 103.697 1.00 24.11  ? 74  GLY A O   1 
ATOM   464   N N   . ASP A 1 75  ? 162.610 126.379 105.454 1.00 26.55  ? 75  ASP A N   1 
ATOM   465   C CA  . ASP A 1 75  ? 163.571 127.404 105.074 1.00 26.55  ? 75  ASP A CA  1 
ATOM   466   C C   . ASP A 1 75  ? 164.982 126.818 105.092 1.00 26.55  ? 75  ASP A C   1 
ATOM   467   O O   . ASP A 1 75  ? 165.339 126.096 106.029 1.00 26.55  ? 75  ASP A O   1 
ATOM   468   C CB  . ASP A 1 75  ? 163.474 128.591 106.036 1.00 26.55  ? 75  ASP A CB  1 
ATOM   469   C CG  . ASP A 1 75  ? 163.875 129.907 105.398 1.00 26.55  ? 75  ASP A CG  1 
ATOM   470   O OD1 . ASP A 1 75  ? 165.020 130.021 104.917 1.00 26.55  ? 75  ASP A OD1 1 
ATOM   471   O OD2 . ASP A 1 75  ? 163.042 130.835 105.389 1.00 26.55  ? 75  ASP A OD2 1 
ATOM   472   N N   . PRO A 1 76  ? 165.800 127.090 104.071 1.00 27.79  ? 76  PRO A N   1 
ATOM   473   C CA  . PRO A 1 76  ? 167.131 126.461 104.008 1.00 27.79  ? 76  PRO A CA  1 
ATOM   474   C C   . PRO A 1 76  ? 168.005 126.725 105.221 1.00 27.79  ? 76  PRO A C   1 
ATOM   475   O O   . PRO A 1 76  ? 168.791 125.848 105.601 1.00 27.79  ? 76  PRO A O   1 
ATOM   476   C CB  . PRO A 1 76  ? 167.737 127.067 102.737 1.00 27.79  ? 76  PRO A CB  1 
ATOM   477   C CG  . PRO A 1 76  ? 166.565 127.356 101.881 1.00 27.79  ? 76  PRO A CG  1 
ATOM   478   C CD  . PRO A 1 76  ? 165.456 127.770 102.811 1.00 27.79  ? 76  PRO A CD  1 
ATOM   479   N N   . HIS A 1 77  ? 167.901 127.897 105.842 1.00 27.68  ? 77  HIS A N   1 
ATOM   480   C CA  . HIS A 1 77  ? 168.651 128.155 107.065 1.00 27.68  ? 77  HIS A CA  1 
ATOM   481   C C   . HIS A 1 77  ? 167.936 127.637 108.305 1.00 27.68  ? 77  HIS A C   1 
ATOM   482   O O   . HIS A 1 77  ? 168.465 127.777 109.412 1.00 27.68  ? 77  HIS A O   1 
ATOM   483   C CB  . HIS A 1 77  ? 168.952 129.654 107.198 1.00 27.68  ? 77  HIS A CB  1 
ATOM   484   C CG  . HIS A 1 77  ? 167.855 130.451 107.834 1.00 27.68  ? 77  HIS A CG  1 
ATOM   485   N ND1 . HIS A 1 77  ? 166.722 130.838 107.151 1.00 27.68  ? 77  HIS A ND1 1 
ATOM   486   C CD2 . HIS A 1 77  ? 167.732 130.960 109.083 1.00 27.68  ? 77  HIS A CD2 1 
ATOM   487   C CE1 . HIS A 1 77  ? 165.943 131.538 107.956 1.00 27.68  ? 77  HIS A CE1 1 
ATOM   488   N NE2 . HIS A 1 77  ? 166.533 131.626 109.134 1.00 27.68  ? 77  HIS A NE2 1 
ATOM   489   N N   . CYS A 1 78  ? 166.758 127.033 108.140 1.00 28.51  ? 78  CYS A N   1 
ATOM   490   C CA  . CYS A 1 78  ? 166.016 126.407 109.227 1.00 28.51  ? 78  CYS A CA  1 
ATOM   491   C C   . CYS A 1 78  ? 165.971 124.889 109.091 1.00 28.51  ? 78  CYS A C   1 
ATOM   492   O O   . CYS A 1 78  ? 165.078 124.246 109.650 1.00 28.51  ? 78  CYS A O   1 
ATOM   493   C CB  . CYS A 1 78  ? 164.596 126.970 109.291 1.00 28.51  ? 78  CYS A CB  1 
ATOM   494   S SG  . CYS A 1 78  ? 164.504 128.758 109.497 1.00 28.51  ? 78  CYS A SG  1 
ATOM   495   N N   . ASP A 1 79  ? 166.916 124.302 108.356 1.00 29.69  ? 79  ASP A N   1 
ATOM   496   C CA  . ASP A 1 79  ? 166.893 122.871 108.082 1.00 29.69  ? 79  ASP A CA  1 
ATOM   497   C C   . ASP A 1 79  ? 167.382 122.028 109.252 1.00 29.69  ? 79  ASP A C   1 
ATOM   498   O O   . ASP A 1 79  ? 167.266 120.799 109.197 1.00 29.69  ? 79  ASP A O   1 
ATOM   499   C CB  . ASP A 1 79  ? 167.735 122.559 106.842 1.00 29.69  ? 79  ASP A CB  1 
ATOM   500   C CG  . ASP A 1 79  ? 166.958 122.736 105.551 1.00 29.69  ? 79  ASP A CG  1 
ATOM   501   O OD1 . ASP A 1 79  ? 165.717 122.859 105.612 1.00 29.69  ? 79  ASP A OD1 1 
ATOM   502   O OD2 . ASP A 1 79  ? 167.590 122.751 104.474 1.00 29.69  ? 79  ASP A OD2 1 
ATOM   503   N N   . VAL A 1 80  ? 167.925 122.650 110.301 1.00 30.21  ? 80  VAL A N   1 
ATOM   504   C CA  . VAL A 1 80  ? 168.339 121.907 111.489 1.00 30.21  ? 80  VAL A CA  1 
ATOM   505   C C   . VAL A 1 80  ? 167.161 121.564 112.387 1.00 30.21  ? 80  VAL A C   1 
ATOM   506   O O   . VAL A 1 80  ? 167.314 120.776 113.328 1.00 30.21  ? 80  VAL A O   1 
ATOM   507   C CB  . VAL A 1 80  ? 169.404 122.717 112.255 1.00 30.21  ? 80  VAL A CB  1 
ATOM   508   C CG1 . VAL A 1 80  ? 168.779 123.933 112.923 1.00 30.21  ? 80  VAL A CG1 1 
ATOM   509   C CG2 . VAL A 1 80  ? 170.157 121.847 113.256 1.00 30.21  ? 80  VAL A CG2 1 
ATOM   510   N N   . PHE A 1 81  ? 165.979 122.113 112.106 1.00 28.50  ? 81  PHE A N   1 
ATOM   511   C CA  . PHE A 1 81  ? 164.791 121.911 112.922 1.00 28.50  ? 81  PHE A CA  1 
ATOM   512   C C   . PHE A 1 81  ? 163.870 120.834 112.359 1.00 28.50  ? 81  PHE A C   1 
ATOM   513   O O   . PHE A 1 81  ? 162.706 120.753 112.762 1.00 28.50  ? 81  PHE A O   1 
ATOM   514   C CB  . PHE A 1 81  ? 164.026 123.226 113.071 1.00 28.50  ? 81  PHE A CB  1 
ATOM   515   C CG  . PHE A 1 81  ? 164.695 124.216 113.977 1.00 28.50  ? 81  PHE A CG  1 
ATOM   516   C CD1 . PHE A 1 81  ? 164.537 124.137 115.348 1.00 28.50  ? 81  PHE A CD1 1 
ATOM   517   C CD2 . PHE A 1 81  ? 165.483 125.227 113.455 1.00 28.50  ? 81  PHE A CD2 1 
ATOM   518   C CE1 . PHE A 1 81  ? 165.152 125.046 116.182 1.00 28.50  ? 81  PHE A CE1 1 
ATOM   519   C CE2 . PHE A 1 81  ? 166.101 126.138 114.284 1.00 28.50  ? 81  PHE A CE2 1 
ATOM   520   C CZ  . PHE A 1 81  ? 165.935 126.048 115.649 1.00 28.50  ? 81  PHE A CZ  1 
ATOM   521   N N   . GLN A 1 82  ? 164.362 120.013 111.436 1.00 29.60  ? 82  GLN A N   1 
ATOM   522   C CA  . GLN A 1 82  ? 163.523 118.992 110.824 1.00 29.60  ? 82  GLN A CA  1 
ATOM   523   C C   . GLN A 1 82  ? 163.267 117.852 111.803 1.00 29.60  ? 82  GLN A C   1 
ATOM   524   O O   . GLN A 1 82  ? 164.197 117.342 112.434 1.00 29.60  ? 82  GLN A O   1 
ATOM   525   C CB  . GLN A 1 82  ? 164.179 118.458 109.553 1.00 29.60  ? 82  GLN A CB  1 
ATOM   526   C CG  . GLN A 1 82  ? 164.164 119.435 108.391 1.00 29.60  ? 82  GLN A CG  1 
ATOM   527   C CD  . GLN A 1 82  ? 164.572 118.786 107.085 1.00 29.60  ? 82  GLN A CD  1 
ATOM   528   O OE1 . GLN A 1 82  ? 165.058 117.657 107.065 1.00 29.60  ? 82  GLN A OE1 1 
ATOM   529   N NE2 . GLN A 1 82  ? 164.375 119.500 105.984 1.00 29.60  ? 82  GLN A NE2 1 
ATOM   530   N N   . ASP A 1 83  ? 161.998 117.457 111.921 1.00 31.62  ? 83  ASP A N   1 
ATOM   531   C CA  . ASP A 1 83  ? 161.578 116.344 112.775 1.00 31.62  ? 83  ASP A CA  1 
ATOM   532   C C   . ASP A 1 83  ? 161.945 116.594 114.237 1.00 31.62  ? 83  ASP A C   1 
ATOM   533   O O   . ASP A 1 83  ? 162.494 115.731 114.923 1.00 31.62  ? 83  ASP A O   1 
ATOM   534   C CB  . ASP A 1 83  ? 162.162 115.019 112.277 1.00 31.62  ? 83  ASP A CB  1 
ATOM   535   C CG  . ASP A 1 83  ? 161.536 114.560 110.974 1.00 31.62  ? 83  ASP A CG  1 
ATOM   536   O OD1 . ASP A 1 83  ? 160.362 114.901 110.724 1.00 31.62  ? 83  ASP A OD1 1 
ATOM   537   O OD2 . ASP A 1 83  ? 162.220 113.864 110.196 1.00 31.62  ? 83  ASP A OD2 1 
ATOM   538   N N   . GLU A 1 84  ? 161.629 117.793 114.714 1.00 31.82  ? 84  GLU A N   1 
ATOM   539   C CA  . GLU A 1 84  ? 161.903 118.194 116.084 1.00 31.82  ? 84  GLU A CA  1 
ATOM   540   C C   . GLU A 1 84  ? 160.650 118.080 116.944 1.00 31.82  ? 84  GLU A C   1 
ATOM   541   O O   . GLU A 1 84  ? 159.527 117.978 116.445 1.00 31.82  ? 84  GLU A O   1 
ATOM   542   C CB  . GLU A 1 84  ? 162.436 119.628 116.134 1.00 31.82  ? 84  GLU A CB  1 
ATOM   543   C CG  . GLU A 1 84  ? 163.887 119.769 115.720 1.00 31.82  ? 84  GLU A CG  1 
ATOM   544   C CD  . GLU A 1 84  ? 164.852 119.553 116.867 1.00 31.82  ? 84  GLU A CD  1 
ATOM   545   O OE1 . GLU A 1 84  ? 164.448 118.957 117.887 1.00 31.82  ? 84  GLU A OE1 1 
ATOM   546   O OE2 . GLU A 1 84  ? 166.018 119.984 116.751 1.00 31.82  ? 84  GLU A OE2 1 
ATOM   547   N N   . LYS A 1 85  ? 160.862 118.100 118.258 1.00 31.78  ? 85  LYS A N   1 
ATOM   548   C CA  . LYS A 1 85  ? 159.774 118.058 119.221 1.00 31.78  ? 85  LYS A CA  1 
ATOM   549   C C   . LYS A 1 85  ? 160.164 118.891 120.432 1.00 31.78  ? 85  LYS A C   1 
ATOM   550   O O   . LYS A 1 85  ? 161.347 119.085 120.720 1.00 31.78  ? 85  LYS A O   1 
ATOM   551   C CB  . LYS A 1 85  ? 159.435 116.619 119.624 1.00 31.78  ? 85  LYS A CB  1 
ATOM   552   C CG  . LYS A 1 85  ? 160.539 115.904 120.373 1.00 31.78  ? 85  LYS A CG  1 
ATOM   553   C CD  . LYS A 1 85  ? 160.105 114.504 120.764 1.00 31.78  ? 85  LYS A CD  1 
ATOM   554   C CE  . LYS A 1 85  ? 160.040 113.592 119.548 1.00 31.78  ? 85  LYS A CE  1 
ATOM   555   N NZ  . LYS A 1 85  ? 161.382 113.357 118.948 1.00 31.78  ? 85  LYS A NZ  1 
ATOM   556   N N   . TRP A 1 86  ? 159.153 119.386 121.140 1.00 27.93  ? 86  TRP A N   1 
ATOM   557   C CA  . TRP A 1 86  ? 159.396 120.345 122.206 1.00 27.93  ? 86  TRP A CA  1 
ATOM   558   C C   . TRP A 1 86  ? 158.234 120.326 123.186 1.00 27.93  ? 86  TRP A C   1 
ATOM   559   O O   . TRP A 1 86  ? 157.140 119.850 122.876 1.00 27.93  ? 86  TRP A O   1 
ATOM   560   C CB  . TRP A 1 86  ? 159.580 121.759 121.645 1.00 27.93  ? 86  TRP A CB  1 
ATOM   561   C CG  . TRP A 1 86  ? 158.357 122.274 120.939 1.00 27.93  ? 86  TRP A CG  1 
ATOM   562   C CD1 . TRP A 1 86  ? 157.311 122.946 121.498 1.00 27.93  ? 86  TRP A CD1 1 
ATOM   563   C CD2 . TRP A 1 86  ? 158.051 122.145 119.546 1.00 27.93  ? 86  TRP A CD2 1 
ATOM   564   N NE1 . TRP A 1 86  ? 156.376 123.248 120.542 1.00 27.93  ? 86  TRP A NE1 1 
ATOM   565   C CE2 . TRP A 1 86  ? 156.806 122.767 119.334 1.00 27.93  ? 86  TRP A CE2 1 
ATOM   566   C CE3 . TRP A 1 86  ? 158.709 121.566 118.457 1.00 27.93  ? 86  TRP A CE3 1 
ATOM   567   C CZ2 . TRP A 1 86  ? 156.208 122.827 118.079 1.00 27.93  ? 86  TRP A CZ2 1 
ATOM   568   C CZ3 . TRP A 1 86  ? 158.114 121.626 117.215 1.00 27.93  ? 86  TRP A CZ3 1 
ATOM   569   C CH2 . TRP A 1 86  ? 156.876 122.252 117.036 1.00 27.93  ? 86  TRP A CH2 1 
ATOM   570   N N   . ASP A 1 87  ? 158.497 120.852 124.380 1.00 25.20  ? 87  ASP A N   1 
ATOM   571   C CA  . ASP A 1 87  ? 157.453 121.242 125.319 1.00 25.20  ? 87  ASP A CA  1 
ATOM   572   C C   . ASP A 1 87  ? 157.151 122.730 125.246 1.00 25.20  ? 87  ASP A C   1 
ATOM   573   O O   . ASP A 1 87  ? 155.988 123.130 125.344 1.00 25.20  ? 87  ASP A O   1 
ATOM   574   C CB  . ASP A 1 87  ? 157.853 120.871 126.750 1.00 25.20  ? 87  ASP A CB  1 
ATOM   575   C CG  . ASP A 1 87  ? 157.496 119.443 127.105 1.00 25.20  ? 87  ASP A CG  1 
ATOM   576   O OD1 . ASP A 1 87  ? 156.417 118.977 126.688 1.00 25.20  ? 87  ASP A OD1 1 
ATOM   577   O OD2 . ASP A 1 87  ? 158.295 118.787 127.803 1.00 25.20  ? 87  ASP A OD2 1 
ATOM   578   N N   . LEU A 1 88  ? 158.180 123.556 125.074 1.00 24.45  ? 88  LEU A N   1 
ATOM   579   C CA  . LEU A 1 88  ? 158.022 124.984 124.843 1.00 24.45  ? 88  LEU A CA  1 
ATOM   580   C C   . LEU A 1 88  ? 158.958 125.407 123.723 1.00 24.45  ? 88  LEU A C   1 
ATOM   581   O O   . LEU A 1 88  ? 160.141 125.060 123.738 1.00 24.45  ? 88  LEU A O   1 
ATOM   582   C CB  . LEU A 1 88  ? 158.317 125.794 126.111 1.00 24.45  ? 88  LEU A CB  1 
ATOM   583   C CG  . LEU A 1 88  ? 158.000 127.290 126.041 1.00 24.45  ? 88  LEU A CG  1 
ATOM   584   C CD1 . LEU A 1 88  ? 156.504 127.530 126.101 1.00 24.45  ? 88  LEU A CD1 1 
ATOM   585   C CD2 . LEU A 1 88  ? 158.715 128.041 127.148 1.00 24.45  ? 88  LEU A CD2 1 
ATOM   586   N N   . PHE A 1 89  ? 158.425 126.146 122.755 1.00 22.60  ? 89  PHE A N   1 
ATOM   587   C CA  . PHE A 1 89  ? 159.210 126.720 121.672 1.00 22.60  ? 89  PHE A CA  1 
ATOM   588   C C   . PHE A 1 89  ? 159.465 128.189 121.980 1.00 22.60  ? 89  PHE A C   1 
ATOM   589   O O   . PHE A 1 89  ? 158.527 128.933 122.284 1.00 22.60  ? 89  PHE A O   1 
ATOM   590   C CB  . PHE A 1 89  ? 158.483 126.570 120.333 1.00 22.60  ? 89  PHE A CB  1 
ATOM   591   C CG  . PHE A 1 89  ? 159.363 126.779 119.131 1.00 22.60  ? 89  PHE A CG  1 
ATOM   592   C CD1 . PHE A 1 89  ? 159.597 128.052 118.637 1.00 22.60  ? 89  PHE A CD1 1 
ATOM   593   C CD2 . PHE A 1 89  ? 159.946 125.702 118.490 1.00 22.60  ? 89  PHE A CD2 1 
ATOM   594   C CE1 . PHE A 1 89  ? 160.402 128.246 117.534 1.00 22.60  ? 89  PHE A CE1 1 
ATOM   595   C CE2 . PHE A 1 89  ? 160.752 125.890 117.385 1.00 22.60  ? 89  PHE A CE2 1 
ATOM   596   C CZ  . PHE A 1 89  ? 160.980 127.164 116.907 1.00 22.60  ? 89  PHE A CZ  1 
ATOM   597   N N   . VAL A 1 90  ? 160.726 128.602 121.908 1.00 23.57  ? 90  VAL A N   1 
ATOM   598   C CA  . VAL A 1 90  ? 161.126 129.968 122.228 1.00 23.57  ? 90  VAL A CA  1 
ATOM   599   C C   . VAL A 1 90  ? 161.490 130.676 120.932 1.00 23.57  ? 90  VAL A C   1 
ATOM   600   O O   . VAL A 1 90  ? 162.416 130.260 120.225 1.00 23.57  ? 90  VAL A O   1 
ATOM   601   C CB  . VAL A 1 90  ? 162.296 130.001 123.223 1.00 23.57  ? 90  VAL A CB  1 
ATOM   602   C CG1 . VAL A 1 90  ? 162.697 131.434 123.516 1.00 23.57  ? 90  VAL A CG1 1 
ATOM   603   C CG2 . VAL A 1 90  ? 161.913 129.287 124.505 1.00 23.57  ? 90  VAL A CG2 1 
ATOM   604   N N   . GLU A 1 91  ? 160.764 131.747 120.624 1.00 24.98  ? 91  GLU A N   1 
ATOM   605   C CA  . GLU A 1 91  ? 160.995 132.542 119.426 1.00 24.98  ? 91  GLU A CA  1 
ATOM   606   C C   . GLU A 1 91  ? 161.742 133.812 119.810 1.00 24.98  ? 91  GLU A C   1 
ATOM   607   O O   . GLU A 1 91  ? 161.269 134.586 120.649 1.00 24.98  ? 91  GLU A O   1 
ATOM   608   C CB  . GLU A 1 91  ? 159.675 132.885 118.735 1.00 24.98  ? 91  GLU A CB  1 
ATOM   609   C CG  . GLU A 1 91  ? 159.289 131.935 117.615 1.00 24.98  ? 91  GLU A CG  1 
ATOM   610   C CD  . GLU A 1 91  ? 158.072 132.406 116.844 1.00 24.98  ? 91  GLU A CD  1 
ATOM   611   O OE1 . GLU A 1 91  ? 157.464 133.417 117.250 1.00 24.98  ? 91  GLU A OE1 1 
ATOM   612   O OE2 . GLU A 1 91  ? 157.719 131.762 115.835 1.00 24.98  ? 91  GLU A OE2 1 
ATOM   613   N N   . ARG A 1 92  ? 162.900 134.024 119.196 1.00 27.72  ? 92  ARG A N   1 
ATOM   614   C CA  . ARG A 1 92  ? 163.693 135.217 119.442 1.00 27.72  ? 92  ARG A CA  1 
ATOM   615   C C   . ARG A 1 92  ? 163.212 136.366 118.563 1.00 27.72  ? 92  ARG A C   1 
ATOM   616   O O   . ARG A 1 92  ? 162.556 136.167 117.538 1.00 27.72  ? 92  ARG A O   1 
ATOM   617   C CB  . ARG A 1 92  ? 165.175 134.944 119.187 1.00 27.72  ? 92  ARG A CB  1 
ATOM   618   C CG  . ARG A 1 92  ? 165.700 133.679 119.845 1.00 27.72  ? 92  ARG A CG  1 
ATOM   619   C CD  . ARG A 1 92  ? 165.416 133.670 121.336 1.00 27.72  ? 92  ARG A CD  1 
ATOM   620   N NE  . ARG A 1 92  ? 166.290 132.751 122.055 1.00 27.72  ? 92  ARG A NE  1 
ATOM   621   C CZ  . ARG A 1 92  ? 166.335 132.640 123.375 1.00 27.72  ? 92  ARG A CZ  1 
ATOM   622   N NH1 . ARG A 1 92  ? 165.564 133.376 124.157 1.00 27.72  ? 92  ARG A NH1 1 
ATOM   623   N NH2 . ARG A 1 92  ? 167.176 131.768 123.924 1.00 27.72  ? 92  ARG A NH2 1 
ATOM   624   N N   . SER A 1 93  ? 163.548 137.585 118.982 1.00 30.29  ? 93  SER A N   1 
ATOM   625   C CA  . SER A 1 93  ? 163.170 138.777 118.235 1.00 30.29  ? 93  SER A CA  1 
ATOM   626   C C   . SER A 1 93  ? 164.062 139.029 117.028 1.00 30.29  ? 93  SER A C   1 
ATOM   627   O O   . SER A 1 93  ? 163.737 139.895 116.209 1.00 30.29  ? 93  SER A O   1 
ATOM   628   C CB  . SER A 1 93  ? 163.192 140.002 119.152 1.00 30.29  ? 93  SER A CB  1 
ATOM   629   O OG  . SER A 1 93  ? 164.505 140.515 119.288 1.00 30.29  ? 93  SER A OG  1 
ATOM   630   N N   . SER A 1 94  ? 165.167 138.298 116.895 1.00 29.56  ? 94  SER A N   1 
ATOM   631   C CA  . SER A 1 94  ? 166.100 138.470 115.793 1.00 29.56  ? 94  SER A CA  1 
ATOM   632   C C   . SER A 1 94  ? 165.867 137.474 114.663 1.00 29.56  ? 94  SER A C   1 
ATOM   633   O O   . SER A 1 94  ? 166.713 137.357 113.771 1.00 29.56  ? 94  SER A O   1 
ATOM   634   C CB  . SER A 1 94  ? 167.538 138.359 116.303 1.00 29.56  ? 94  SER A CB  1 
ATOM   635   O OG  . SER A 1 94  ? 167.721 137.175 117.058 1.00 29.56  ? 94  SER A OG  1 
ATOM   636   N N   . ALA A 1 95  ? 164.748 136.756 114.682 1.00 28.34  ? 95  ALA A N   1 
ATOM   637   C CA  . ALA A 1 95  ? 164.435 135.814 113.618 1.00 28.34  ? 95  ALA A CA  1 
ATOM   638   C C   . ALA A 1 95  ? 164.120 136.547 112.318 1.00 28.34  ? 95  ALA A C   1 
ATOM   639   O O   . ALA A 1 95  ? 163.589 137.661 112.317 1.00 28.34  ? 95  ALA A O   1 
ATOM   640   C CB  . ALA A 1 95  ? 163.255 134.931 114.019 1.00 28.34  ? 95  ALA A CB  1 
ATOM   641   N N   . PHE A 1 96  ? 164.452 135.906 111.199 1.00 26.79  ? 96  PHE A N   1 
ATOM   642   C CA  . PHE A 1 96  ? 164.241 136.498 109.887 1.00 26.79  ? 96  PHE A CA  1 
ATOM   643   C C   . PHE A 1 96  ? 163.934 135.398 108.880 1.00 26.79  ? 96  PHE A C   1 
ATOM   644   O O   . PHE A 1 96  ? 164.148 134.211 109.136 1.00 26.79  ? 96  PHE A O   1 
ATOM   645   C CB  . PHE A 1 96  ? 165.453 137.328 109.444 1.00 26.79  ? 96  PHE A CB  1 
ATOM   646   C CG  . PHE A 1 96  ? 166.729 136.541 109.340 1.00 26.79  ? 96  PHE A CG  1 
ATOM   647   C CD1 . PHE A 1 96  ? 167.557 136.391 110.438 1.00 26.79  ? 96  PHE A CD1 1 
ATOM   648   C CD2 . PHE A 1 96  ? 167.108 135.964 108.140 1.00 26.79  ? 96  PHE A CD2 1 
ATOM   649   C CE1 . PHE A 1 96  ? 168.731 135.672 110.344 1.00 26.79  ? 96  PHE A CE1 1 
ATOM   650   C CE2 . PHE A 1 96  ? 168.280 135.243 108.041 1.00 26.79  ? 96  PHE A CE2 1 
ATOM   651   C CZ  . PHE A 1 96  ? 169.093 135.098 109.144 1.00 26.79  ? 96  PHE A CZ  1 
ATOM   652   N N   . SER A 1 97  ? 163.420 135.812 107.724 1.00 25.57  ? 97  SER A N   1 
ATOM   653   C CA  . SER A 1 97  ? 163.096 134.915 106.625 1.00 25.57  ? 97  SER A CA  1 
ATOM   654   C C   . SER A 1 97  ? 164.083 135.125 105.486 1.00 25.57  ? 97  SER A C   1 
ATOM   655   O O   . SER A 1 97  ? 164.465 136.259 105.185 1.00 25.57  ? 97  SER A O   1 
ATOM   656   C CB  . SER A 1 97  ? 161.667 135.150 106.128 1.00 25.57  ? 97  SER A CB  1 
ATOM   657   O OG  . SER A 1 97  ? 160.715 134.634 107.041 1.00 25.57  ? 97  SER A OG  1 
ATOM   658   N N   . ASN A 1 98  ? 164.501 134.027 104.858 1.00 26.05  ? 98  ASN A N   1 
ATOM   659   C CA  . ASN A 1 98  ? 165.508 134.069 103.803 1.00 26.05  ? 98  ASN A CA  1 
ATOM   660   C C   . ASN A 1 98  ? 165.131 133.138 102.657 1.00 26.05  ? 98  ASN A C   1 
ATOM   661   O O   . ASN A 1 98  ? 165.971 132.399 102.132 1.00 26.05  ? 98  ASN A O   1 
ATOM   662   C CB  . ASN A 1 98  ? 166.890 133.716 104.353 1.00 26.05  ? 98  ASN A CB  1 
ATOM   663   C CG  . ASN A 1 98  ? 168.013 134.346 103.558 1.00 26.05  ? 98  ASN A CG  1 
ATOM   664   O OD1 . ASN A 1 98  ? 167.860 135.430 103.000 1.00 26.05  ? 98  ASN A OD1 1 
ATOM   665   N ND2 . ASN A 1 98  ? 169.152 133.669 103.507 1.00 26.05  ? 98  ASN A ND2 1 
ATOM   666   N N   . CYS A 1 99  ? 163.868 133.160 102.250 1.00 24.80  ? 99  CYS A N   1 
ATOM   667   C CA  . CYS A 1 99  ? 163.389 132.310 101.164 1.00 24.80  ? 99  CYS A CA  1 
ATOM   668   C C   . CYS A 1 99  ? 162.403 133.124 100.332 1.00 24.80  ? 99  CYS A C   1 
ATOM   669   O O   . CYS A 1 99  ? 162.356 134.356 100.413 1.00 24.80  ? 99  CYS A O   1 
ATOM   670   C CB  . CYS A 1 99  ? 162.788 131.008 101.716 1.00 24.80  ? 99  CYS A CB  1 
ATOM   671   S SG  . CYS A 1 99  ? 162.548 129.698 100.483 1.00 24.80  ? 99  CYS A SG  1 
ATOM   672   N N   . PRO A 1 101 ? 159.291 135.090 99.158  1.00 21.22  ? 101 PRO A N   1 
ATOM   673   C CA  . PRO A 1 101 ? 158.282 135.826 99.931  1.00 21.22  ? 101 PRO A CA  1 
ATOM   674   C C   . PRO A 1 101 ? 156.935 135.117 99.909  1.00 21.22  ? 101 PRO A C   1 
ATOM   675   O O   . PRO A 1 101 ? 156.520 134.560 98.891  1.00 21.22  ? 101 PRO A O   1 
ATOM   676   C CB  . PRO A 1 101 ? 158.215 137.187 99.226  1.00 21.22  ? 101 PRO A CB  1 
ATOM   677   C CG  . PRO A 1 101 ? 158.868 136.981 97.897  1.00 21.22  ? 101 PRO A CG  1 
ATOM   678   C CD  . PRO A 1 101 ? 159.889 135.918 98.099  1.00 21.22  ? 101 PRO A CD  1 
ATOM   679   N N   . TYR A 1 102 ? 156.248 135.150 101.047 1.00 19.88  ? 102 TYR A N   1 
ATOM   680   C CA  . TYR A 1 102 ? 154.993 134.432 101.201 1.00 19.88  ? 102 TYR A CA  1 
ATOM   681   C C   . TYR A 1 102 ? 154.121 135.153 102.218 1.00 19.88  ? 102 TYR A C   1 
ATOM   682   O O   . TYR A 1 102 ? 154.574 136.045 102.938 1.00 19.88  ? 102 TYR A O   1 
ATOM   683   C CB  . TYR A 1 102 ? 155.230 132.976 101.625 1.00 19.88  ? 102 TYR A CB  1 
ATOM   684   C CG  . TYR A 1 102 ? 155.704 132.813 103.055 1.00 19.88  ? 102 TYR A CG  1 
ATOM   685   C CD1 . TYR A 1 102 ? 157.054 132.871 103.369 1.00 19.88  ? 102 TYR A CD1 1 
ATOM   686   C CD2 . TYR A 1 102 ? 154.802 132.596 104.089 1.00 19.88  ? 102 TYR A CD2 1 
ATOM   687   C CE1 . TYR A 1 102 ? 157.491 132.724 104.670 1.00 19.88  ? 102 TYR A CE1 1 
ATOM   688   C CE2 . TYR A 1 102 ? 155.230 132.450 105.392 1.00 19.88  ? 102 TYR A CE2 1 
ATOM   689   C CZ  . TYR A 1 102 ? 156.576 132.513 105.677 1.00 19.88  ? 102 TYR A CZ  1 
ATOM   690   O OH  . TYR A 1 102 ? 157.010 132.365 106.973 1.00 19.88  ? 102 TYR A OH  1 
ATOM   691   N N   . ASP A 1 103 ? 152.853 134.754 102.265 1.00 20.04  ? 103 ASP A N   1 
ATOM   692   C CA  . ASP A 1 103 ? 151.934 135.219 103.291 1.00 20.04  ? 103 ASP A CA  1 
ATOM   693   C C   . ASP A 1 103 ? 151.011 134.072 103.670 1.00 20.04  ? 103 ASP A C   1 
ATOM   694   O O   . ASP A 1 103 ? 150.725 133.192 102.854 1.00 20.04  ? 103 ASP A O   1 
ATOM   695   C CB  . ASP A 1 103 ? 151.118 136.431 102.827 1.00 20.04  ? 103 ASP A CB  1 
ATOM   696   C CG  . ASP A 1 103 ? 150.175 136.100 101.689 1.00 20.04  ? 103 ASP A CG  1 
ATOM   697   O OD1 . ASP A 1 103 ? 150.636 136.045 100.529 1.00 20.04  ? 103 ASP A OD1 1 
ATOM   698   O OD2 . ASP A 1 103 ? 148.971 135.899 101.952 1.00 20.04  ? 103 ASP A OD2 1 
ATOM   699   N N   . VAL A 1 104 ? 150.554 134.085 104.917 1.00 18.88  ? 104 VAL A N   1 
ATOM   700   C CA  . VAL A 1 104 ? 149.671 133.039 105.427 1.00 18.88  ? 104 VAL A CA  1 
ATOM   701   C C   . VAL A 1 104 ? 148.348 133.662 105.851 1.00 18.88  ? 104 VAL A C   1 
ATOM   702   O O   . VAL A 1 104 ? 148.301 134.379 106.860 1.00 18.88  ? 104 VAL A O   1 
ATOM   703   C CB  . VAL A 1 104 ? 150.318 132.281 106.597 1.00 18.88  ? 104 VAL A CB  1 
ATOM   704   C CG1 . VAL A 1 104 ? 149.415 131.151 107.059 1.00 18.88  ? 104 VAL A CG1 1 
ATOM   705   C CG2 . VAL A 1 104 ? 151.682 131.747 106.199 1.00 18.88  ? 104 VAL A CG2 1 
ATOM   706   N N   . PRO A 1 105 ? 147.261 133.440 105.115 1.00 20.85  ? 105 PRO A N   1 
ATOM   707   C CA  . PRO A 1 105 ? 145.948 133.881 105.602 1.00 20.85  ? 105 PRO A CA  1 
ATOM   708   C C   . PRO A 1 105 ? 145.597 133.171 106.901 1.00 20.85  ? 105 PRO A C   1 
ATOM   709   O O   . PRO A 1 105 ? 145.644 131.942 106.988 1.00 20.85  ? 105 PRO A O   1 
ATOM   710   C CB  . PRO A 1 105 ? 144.998 133.497 104.462 1.00 20.85  ? 105 PRO A CB  1 
ATOM   711   C CG  . PRO A 1 105 ? 145.872 133.372 103.258 1.00 20.85  ? 105 PRO A CG  1 
ATOM   712   C CD  . PRO A 1 105 ? 147.187 132.870 103.760 1.00 20.85  ? 105 PRO A CD  1 
ATOM   713   N N   . ASP A 1 106 ? 145.247 133.964 107.914 1.00 21.91  ? 106 ASP A N   1 
ATOM   714   C CA  . ASP A 1 106 ? 145.010 133.479 109.275 1.00 21.91  ? 106 ASP A CA  1 
ATOM   715   C C   . ASP A 1 106 ? 146.275 132.810 109.824 1.00 21.91  ? 106 ASP A C   1 
ATOM   716   O O   . ASP A 1 106 ? 146.308 131.619 110.137 1.00 21.91  ? 106 ASP A O   1 
ATOM   717   C CB  . ASP A 1 106 ? 143.799 132.539 109.322 1.00 21.91  ? 106 ASP A CB  1 
ATOM   718   C CG  . ASP A 1 106 ? 143.383 132.187 110.736 1.00 21.91  ? 106 ASP A CG  1 
ATOM   719   O OD1 . ASP A 1 106 ? 144.045 132.643 111.692 1.00 21.91  ? 106 ASP A OD1 1 
ATOM   720   O OD2 . ASP A 1 106 ? 142.388 131.448 110.893 1.00 21.91  ? 106 ASP A OD2 1 
ATOM   721   N N   . TYR A 1 107 ? 147.331 133.622 109.921 1.00 20.66  ? 107 TYR A N   1 
ATOM   722   C CA  . TYR A 1 107 ? 148.636 133.143 110.371 1.00 20.66  ? 107 TYR A CA  1 
ATOM   723   C C   . TYR A 1 107 ? 148.589 132.651 111.814 1.00 20.66  ? 107 TYR A C   1 
ATOM   724   O O   . TYR A 1 107 ? 149.220 131.641 112.158 1.00 20.66  ? 107 TYR A O   1 
ATOM   725   C CB  . TYR A 1 107 ? 149.657 134.273 110.203 1.00 20.66  ? 107 TYR A CB  1 
ATOM   726   C CG  . TYR A 1 107 ? 151.053 134.001 110.716 1.00 20.66  ? 107 TYR A CG  1 
ATOM   727   C CD1 . TYR A 1 107 ? 151.389 134.245 112.042 1.00 20.66  ? 107 TYR A CD1 1 
ATOM   728   C CD2 . TYR A 1 107 ? 152.044 133.533 109.867 1.00 20.66  ? 107 TYR A CD2 1 
ATOM   729   C CE1 . TYR A 1 107 ? 152.664 134.009 112.510 1.00 20.66  ? 107 TYR A CE1 1 
ATOM   730   C CE2 . TYR A 1 107 ? 153.323 133.296 110.326 1.00 20.66  ? 107 TYR A CE2 1 
ATOM   731   C CZ  . TYR A 1 107 ? 153.627 133.535 111.648 1.00 20.66  ? 107 TYR A CZ  1 
ATOM   732   O OH  . TYR A 1 107 ? 154.900 133.300 112.110 1.00 20.66  ? 107 TYR A OH  1 
ATOM   733   N N   . ALA A 1 108 ? 147.848 133.358 112.671 1.00 20.04  ? 108 ALA A N   1 
ATOM   734   C CA  . ALA A 1 108 ? 147.847 133.050 114.097 1.00 20.04  ? 108 ALA A CA  1 
ATOM   735   C C   . ALA A 1 108 ? 147.283 131.662 114.376 1.00 20.04  ? 108 ALA A C   1 
ATOM   736   O O   . ALA A 1 108 ? 147.794 130.946 115.242 1.00 20.04  ? 108 ALA A O   1 
ATOM   737   C CB  . ALA A 1 108 ? 147.057 134.113 114.859 1.00 20.04  ? 108 ALA A CB  1 
ATOM   738   N N   . SER A 1 109 ? 146.225 131.268 113.665 1.00 21.33  ? 109 SER A N   1 
ATOM   739   C CA  . SER A 1 109 ? 145.616 129.961 113.905 1.00 21.33  ? 109 SER A CA  1 
ATOM   740   C C   . SER A 1 109 ? 146.582 128.831 113.568 1.00 21.33  ? 109 SER A C   1 
ATOM   741   O O   . SER A 1 109 ? 146.723 127.867 114.331 1.00 21.33  ? 109 SER A O   1 
ATOM   742   C CB  . SER A 1 109 ? 144.330 129.824 113.093 1.00 21.33  ? 109 SER A CB  1 
ATOM   743   O OG  . SER A 1 109 ? 143.291 130.610 113.647 1.00 21.33  ? 109 SER A OG  1 
ATOM   744   N N   . LEU A 1 110 ? 147.254 128.932 112.418 1.00 19.94  ? 110 LEU A N   1 
ATOM   745   C CA  . LEU A 1 110 ? 148.218 127.908 112.035 1.00 19.94  ? 110 LEU A CA  1 
ATOM   746   C C   . LEU A 1 110 ? 149.384 127.861 113.011 1.00 19.94  ? 110 LEU A C   1 
ATOM   747   O O   . LEU A 1 110 ? 149.817 126.776 113.421 1.00 19.94  ? 110 LEU A O   1 
ATOM   748   C CB  . LEU A 1 110 ? 148.718 128.163 110.614 1.00 19.94  ? 110 LEU A CB  1 
ATOM   749   C CG  . LEU A 1 110 ? 149.698 127.138 110.043 1.00 19.94  ? 110 LEU A CG  1 
ATOM   750   C CD1 . LEU A 1 110 ? 149.081 125.749 110.040 1.00 19.94  ? 110 LEU A CD1 1 
ATOM   751   C CD2 . LEU A 1 110 ? 150.135 127.534 108.645 1.00 19.94  ? 110 LEU A CD2 1 
ATOM   752   N N   . ARG A 1 111 ? 149.899 129.030 113.404 1.00 20.75  ? 111 ARG A N   1 
ATOM   753   C CA  . ARG A 1 111 ? 150.988 129.064 114.375 1.00 20.75  ? 111 ARG A CA  1 
ATOM   754   C C   . ARG A 1 111 ? 150.572 128.415 115.690 1.00 20.75  ? 111 ARG A C   1 
ATOM   755   O O   . ARG A 1 111 ? 151.319 127.611 116.261 1.00 20.75  ? 111 ARG A O   1 
ATOM   756   C CB  . ARG A 1 111 ? 151.431 130.509 114.602 1.00 20.75  ? 111 ARG A CB  1 
ATOM   757   C CG  . ARG A 1 111 ? 152.564 130.684 115.598 1.00 20.75  ? 111 ARG A CG  1 
ATOM   758   C CD  . ARG A 1 111 ? 152.840 132.159 115.828 1.00 20.75  ? 111 ARG A CD  1 
ATOM   759   N NE  . ARG A 1 111 ? 153.953 132.388 116.740 1.00 20.75  ? 111 ARG A NE  1 
ATOM   760   C CZ  . ARG A 1 111 ? 153.826 132.599 118.043 1.00 20.75  ? 111 ARG A CZ  1 
ATOM   761   N NH1 . ARG A 1 111 ? 152.641 132.602 118.629 1.00 20.75  ? 111 ARG A NH1 1 
ATOM   762   N NH2 . ARG A 1 111 ? 154.914 132.809 118.776 1.00 20.75  ? 111 ARG A NH2 1 
ATOM   763   N N   . SER A 1 112 ? 149.366 128.732 116.167 1.00 22.36  ? 112 SER A N   1 
ATOM   764   C CA  . SER A 1 112 ? 148.890 128.190 117.433 1.00 22.36  ? 112 SER A CA  1 
ATOM   765   C C   . SER A 1 112 ? 148.718 126.679 117.365 1.00 22.36  ? 112 SER A C   1 
ATOM   766   O O   . SER A 1 112 ? 149.115 125.964 118.292 1.00 22.36  ? 112 SER A O   1 
ATOM   767   C CB  . SER A 1 112 ? 147.575 128.863 117.823 1.00 22.36  ? 112 SER A CB  1 
ATOM   768   O OG  . SER A 1 112 ? 146.882 128.110 118.801 1.00 22.36  ? 112 SER A OG  1 
ATOM   769   N N   . LEU A 1 113 ? 148.133 126.167 116.278 1.00 22.31  ? 113 LEU A N   1 
ATOM   770   C CA  . LEU A 1 113 ? 147.906 124.726 116.214 1.00 22.31  ? 113 LEU A CA  1 
ATOM   771   C C   . LEU A 1 113 ? 149.210 123.960 116.028 1.00 22.31  ? 113 LEU A C   1 
ATOM   772   O O   . LEU A 1 113 ? 149.371 122.873 116.598 1.00 22.31  ? 113 LEU A O   1 
ATOM   773   C CB  . LEU A 1 113 ? 146.898 124.382 115.111 1.00 22.31  ? 113 LEU A CB  1 
ATOM   774   C CG  . LEU A 1 113 ? 147.157 124.595 113.618 1.00 22.31  ? 113 LEU A CG  1 
ATOM   775   C CD1 . LEU A 1 113 ? 147.875 123.404 113.002 1.00 22.31  ? 113 LEU A CD1 1 
ATOM   776   C CD2 . LEU A 1 113 ? 145.846 124.852 112.899 1.00 22.31  ? 113 LEU A CD2 1 
ATOM   777   N N   . ILE A 1 114 ? 150.159 124.507 115.263 1.00 21.71  ? 114 ILE A N   1 
ATOM   778   C CA  . ILE A 1 114 ? 151.460 123.857 115.138 1.00 21.71  ? 114 ILE A CA  1 
ATOM   779   C C   . ILE A 1 114 ? 152.185 123.847 116.478 1.00 21.71  ? 114 ILE A C   1 
ATOM   780   O O   . ILE A 1 114 ? 152.792 122.839 116.860 1.00 21.71  ? 114 ILE A O   1 
ATOM   781   C CB  . ILE A 1 114 ? 152.298 124.534 114.039 1.00 21.71  ? 114 ILE A CB  1 
ATOM   782   C CG1 . ILE A 1 114 ? 151.653 124.314 112.672 1.00 21.71  ? 114 ILE A CG1 1 
ATOM   783   C CG2 . ILE A 1 114 ? 153.714 123.985 114.028 1.00 21.71  ? 114 ILE A CG2 1 
ATOM   784   C CD1 . ILE A 1 114 ? 151.620 122.869 112.252 1.00 21.71  ? 114 ILE A CD1 1 
ATOM   785   N N   . ALA A 1 115 ? 152.138 124.962 117.214 1.00 22.59  ? 115 ALA A N   1 
ATOM   786   C CA  . ALA A 1 115 ? 152.790 125.010 118.519 1.00 22.59  ? 115 ALA A CA  1 
ATOM   787   C C   . ALA A 1 115 ? 152.148 124.038 119.499 1.00 22.59  ? 115 ALA A C   1 
ATOM   788   O O   . ALA A 1 115 ? 152.847 123.362 120.262 1.00 22.59  ? 115 ALA A O   1 
ATOM   789   C CB  . ALA A 1 115 ? 152.749 126.433 119.072 1.00 22.59  ? 115 ALA A CB  1 
ATOM   790   N N   . SER A 1 116 ? 150.815 123.951 119.493 1.00 24.08  ? 116 SER A N   1 
ATOM   791   C CA  . SER A 1 116 ? 150.126 123.053 120.412 1.00 24.08  ? 116 SER A CA  1 
ATOM   792   C C   . SER A 1 116 ? 150.334 121.591 120.041 1.00 24.08  ? 116 SER A C   1 
ATOM   793   O O   . SER A 1 116 ? 150.259 120.719 120.914 1.00 24.08  ? 116 SER A O   1 
ATOM   794   C CB  . SER A 1 116 ? 148.637 123.386 120.449 1.00 24.08  ? 116 SER A CB  1 
ATOM   795   O OG  . SER A 1 116 ? 147.925 122.436 121.219 1.00 24.08  ? 116 SER A OG  1 
ATOM   796   N N   . SER A 1 117 ? 150.584 121.298 118.762 1.00 25.26  ? 117 SER A N   1 
ATOM   797   C CA  . SER A 1 117 ? 150.872 119.922 118.366 1.00 25.26  ? 117 SER A CA  1 
ATOM   798   C C   . SER A 1 117 ? 152.140 119.410 119.041 1.00 25.26  ? 117 SER A C   1 
ATOM   799   O O   . SER A 1 117 ? 152.176 118.283 119.548 1.00 25.26  ? 117 SER A O   1 
ATOM   800   C CB  . SER A 1 117 ? 150.993 119.826 116.846 1.00 25.26  ? 117 SER A CB  1 
ATOM   801   O OG  . SER A 1 117 ? 151.253 118.495 116.442 1.00 25.26  ? 117 SER A OG  1 
ATOM   802   N N   . GLY A 1 118 ? 153.192 120.223 119.058 1.00 24.48  ? 118 GLY A N   1 
ATOM   803   C CA  . GLY A 1 118 ? 154.402 119.879 119.774 1.00 24.48  ? 118 GLY A CA  1 
ATOM   804   C C   . GLY A 1 118 ? 155.416 119.062 119.008 1.00 24.48  ? 118 GLY A C   1 
ATOM   805   O O   . GLY A 1 118 ? 156.373 118.572 119.618 1.00 24.48  ? 118 GLY A O   1 
ATOM   806   N N   . THR A 1 119 ? 155.252 118.904 117.698 1.00 25.66  ? 119 THR A N   1 
ATOM   807   C CA  . THR A 1 119 ? 156.171 118.080 116.928 1.00 25.66  ? 119 THR A CA  1 
ATOM   808   C C   . THR A 1 119 ? 156.219 118.573 115.489 1.00 25.66  ? 119 THR A C   1 
ATOM   809   O O   . THR A 1 119 ? 155.307 119.251 115.011 1.00 25.66  ? 119 THR A O   1 
ATOM   810   C CB  . THR A 1 119 ? 155.767 116.599 116.987 1.00 25.66  ? 119 THR A CB  1 
ATOM   811   O OG1 . THR A 1 119 ? 156.787 115.794 116.385 1.00 25.66  ? 119 THR A OG1 1 
ATOM   812   C CG2 . THR A 1 119 ? 154.439 116.370 116.276 1.00 25.66  ? 119 THR A CG2 1 
ATOM   813   N N   . LEU A 1 120 ? 157.312 118.234 114.808 1.00 25.82  ? 120 LEU A N   1 
ATOM   814   C CA  . LEU A 1 120 ? 157.507 118.532 113.395 1.00 25.82  ? 120 LEU A CA  1 
ATOM   815   C C   . LEU A 1 120 ? 157.813 117.261 112.614 1.00 25.82  ? 120 LEU A C   1 
ATOM   816   O O   . LEU A 1 120 ? 158.671 117.242 111.730 1.00 25.82  ? 120 LEU A O   1 
ATOM   817   C CB  . LEU A 1 120 ? 158.619 119.559 113.191 1.00 25.82  ? 120 LEU A CB  1 
ATOM   818   C CG  . LEU A 1 120 ? 158.251 121.043 113.263 1.00 25.82  ? 120 LEU A CG  1 
ATOM   819   C CD1 . LEU A 1 120 ? 159.486 121.909 113.080 1.00 25.82  ? 120 LEU A CD1 1 
ATOM   820   C CD2 . LEU A 1 120 ? 157.182 121.400 112.242 1.00 25.82  ? 120 LEU A CD2 1 
ATOM   821   N N   . ASP A 1 121 ? 157.105 116.180 112.930 1.00 27.96  ? 121 ASP A N   1 
ATOM   822   C CA  . ASP A 1 121 ? 157.339 114.896 112.283 1.00 27.96  ? 121 ASP A CA  1 
ATOM   823   C C   . ASP A 1 121 ? 156.661 114.880 110.918 1.00 27.96  ? 121 ASP A C   1 
ATOM   824   O O   . ASP A 1 121 ? 155.437 115.014 110.823 1.00 27.96  ? 121 ASP A O   1 
ATOM   825   C CB  . ASP A 1 121 ? 156.822 113.759 113.159 1.00 27.96  ? 121 ASP A CB  1 
ATOM   826   C CG  . ASP A 1 121 ? 157.164 112.394 112.602 1.00 27.96  ? 121 ASP A CG  1 
ATOM   827   O OD1 . ASP A 1 121 ? 158.343 111.993 112.694 1.00 27.96  ? 121 ASP A OD1 1 
ATOM   828   O OD2 . ASP A 1 121 ? 156.256 111.720 112.074 1.00 27.96  ? 121 ASP A OD2 1 
ATOM   829   N N   . PHE A 1 122 ? 157.457 114.711 109.865 1.00 21.34  ? 122 PHE A N   1 
ATOM   830   C CA  . PHE A 1 122 ? 156.987 114.781 108.489 1.00 21.34  ? 122 PHE A CA  1 
ATOM   831   C C   . PHE A 1 122 ? 157.204 113.437 107.810 1.00 21.34  ? 122 PHE A C   1 
ATOM   832   O O   . PHE A 1 122 ? 158.301 112.872 107.880 1.00 21.34  ? 122 PHE A O   1 
ATOM   833   C CB  . PHE A 1 122 ? 157.715 115.892 107.728 1.00 21.34  ? 122 PHE A CB  1 
ATOM   834   C CG  . PHE A 1 122 ? 157.188 116.132 106.343 1.00 21.34  ? 122 PHE A CG  1 
ATOM   835   C CD1 . PHE A 1 122 ? 156.134 117.001 106.132 1.00 21.34  ? 122 PHE A CD1 1 
ATOM   836   C CD2 . PHE A 1 122 ? 157.758 115.502 105.251 1.00 21.34  ? 122 PHE A CD2 1 
ATOM   837   C CE1 . PHE A 1 122 ? 155.654 117.229 104.862 1.00 21.34  ? 122 PHE A CE1 1 
ATOM   838   C CE2 . PHE A 1 122 ? 157.280 115.725 103.979 1.00 21.34  ? 122 PHE A CE2 1 
ATOM   839   C CZ  . PHE A 1 122 ? 156.229 116.591 103.785 1.00 21.34  ? 122 PHE A CZ  1 
ATOM   840   N N   . ILE A 1 123 ? 156.163 112.934 107.150 1.00 21.81  ? 123 ILE A N   1 
ATOM   841   C CA  . ILE A 1 123 ? 156.207 111.670 106.426 1.00 21.81  ? 123 ILE A CA  1 
ATOM   842   C C   . ILE A 1 123 ? 155.992 111.957 104.947 1.00 21.81  ? 123 ILE A C   1 
ATOM   843   O O   . ILE A 1 123 ? 155.034 112.645 104.577 1.00 21.81  ? 123 ILE A O   1 
ATOM   844   C CB  . ILE A 1 123 ? 155.153 110.675 106.947 1.00 21.81  ? 123 ILE A CB  1 
ATOM   845   C CG1 . ILE A 1 123 ? 155.243 110.542 108.469 1.00 21.81  ? 123 ILE A CG1 1 
ATOM   846   C CG2 . ILE A 1 123 ? 155.314 109.324 106.270 1.00 21.81  ? 123 ILE A CG2 1 
ATOM   847   C CD1 . ILE A 1 123 ? 156.378 109.665 108.941 1.00 21.81  ? 123 ILE A CD1 1 
ATOM   848   N N   . THR A 1 124 ? 156.878 111.428 104.108 1.00 25.21  ? 124 THR A N   1 
ATOM   849   C CA  . THR A 1 124 ? 156.810 111.666 102.673 1.00 25.21  ? 124 THR A CA  1 
ATOM   850   C C   . THR A 1 124 ? 155.852 110.688 102.005 1.00 25.21  ? 124 THR A C   1 
ATOM   851   O O   . THR A 1 124 ? 155.898 109.480 102.253 1.00 25.21  ? 124 THR A O   1 
ATOM   852   C CB  . THR A 1 124 ? 158.200 111.542 102.047 1.00 25.21  ? 124 THR A CB  1 
ATOM   853   O OG1 . THR A 1 124 ? 159.098 112.455 102.688 1.00 25.21  ? 124 THR A OG1 1 
ATOM   854   C CG2 . THR A 1 124 ? 158.151 111.852 100.561 1.00 25.21  ? 124 THR A CG2 1 
ATOM   855   N N   . GLU A 1 125 ? 154.982 111.220 101.150 1.00 24.59  ? 125 GLU A N   1 
ATOM   856   C CA  . GLU A 1 125 ? 154.025 110.427 100.395 1.00 24.59  ? 125 GLU A CA  1 
ATOM   857   C C   . GLU A 1 125 ? 154.321 110.551 98.907  1.00 24.59  ? 125 GLU A C   1 
ATOM   858   O O   . GLU A 1 125 ? 154.862 111.561 98.448  1.00 24.59  ? 125 GLU A O   1 
ATOM   859   C CB  . GLU A 1 125 ? 152.587 110.864 100.688 1.00 24.59  ? 125 GLU A CB  1 
ATOM   860   C CG  . GLU A 1 125 ? 152.069 110.380 102.029 1.00 24.59  ? 125 GLU A CG  1 
ATOM   861   C CD  . GLU A 1 125 ? 150.642 110.803 102.296 1.00 24.59  ? 125 GLU A CD  1 
ATOM   862   O OE1 . GLU A 1 125 ? 150.286 111.952 101.963 1.00 24.59  ? 125 GLU A OE1 1 
ATOM   863   O OE2 . GLU A 1 125 ? 149.874 109.984 102.841 1.00 24.59  ? 125 GLU A OE2 1 
ATOM   864   N N   . SER A 1 126 ? 153.962 109.513 98.156  1.00 25.98  ? 126 SER A N   1 
ATOM   865   C CA  . SER A 1 126 ? 154.301 109.424 96.735  1.00 25.98  ? 126 SER A CA  1 
ATOM   866   C C   . SER A 1 126 ? 153.162 110.004 95.907  1.00 25.98  ? 126 SER A C   1 
ATOM   867   O O   . SER A 1 126 ? 152.255 109.295 95.471  1.00 25.98  ? 126 SER A O   1 
ATOM   868   C CB  . SER A 1 126 ? 154.596 107.982 96.346  1.00 25.98  ? 126 SER A CB  1 
ATOM   869   O OG  . SER A 1 126 ? 153.435 107.179 96.455  1.00 25.98  ? 126 SER A OG  1 
ATOM   870   N N   . PHE A 1 127 ? 153.212 111.315 95.687  1.00 25.26  ? 127 PHE A N   1 
ATOM   871   C CA  . PHE A 1 127 ? 152.280 111.974 94.784  1.00 25.26  ? 127 PHE A CA  1 
ATOM   872   C C   . PHE A 1 127 ? 152.770 111.850 93.347  1.00 25.26  ? 127 PHE A C   1 
ATOM   873   O O   . PHE A 1 127 ? 153.973 111.920 93.079  1.00 25.26  ? 127 PHE A O   1 
ATOM   874   C CB  . PHE A 1 127 ? 152.125 113.449 95.153  1.00 25.26  ? 127 PHE A CB  1 
ATOM   875   C CG  . PHE A 1 127 ? 151.333 113.685 96.407  1.00 25.26  ? 127 PHE A CG  1 
ATOM   876   C CD1 . PHE A 1 127 ? 149.950 113.723 96.372  1.00 25.26  ? 127 PHE A CD1 1 
ATOM   877   C CD2 . PHE A 1 127 ? 151.973 113.878 97.619  1.00 25.26  ? 127 PHE A CD2 1 
ATOM   878   C CE1 . PHE A 1 127 ? 149.221 113.945 97.523  1.00 25.26  ? 127 PHE A CE1 1 
ATOM   879   C CE2 . PHE A 1 127 ? 151.249 114.098 98.772  1.00 25.26  ? 127 PHE A CE2 1 
ATOM   880   C CZ  . PHE A 1 127 ? 149.872 114.132 98.724  1.00 25.26  ? 127 PHE A CZ  1 
ATOM   881   N N   . THR A 1 128 ? 151.833 111.666 92.423  1.00 27.97  ? 128 THR A N   1 
ATOM   882   C CA  . THR A 1 128 ? 152.139 111.530 91.004  1.00 27.97  ? 128 THR A CA  1 
ATOM   883   C C   . THR A 1 128 ? 151.557 112.720 90.253  1.00 27.97  ? 128 THR A C   1 
ATOM   884   O O   . THR A 1 128 ? 150.334 112.881 90.191  1.00 27.97  ? 128 THR A O   1 
ATOM   885   C CB  . THR A 1 128 ? 151.585 110.221 90.443  1.00 27.97  ? 128 THR A CB  1 
ATOM   886   O OG1 . THR A 1 128 ? 152.096 109.118 91.202  1.00 27.97  ? 128 THR A OG1 1 
ATOM   887   C CG2 . THR A 1 128 ? 151.989 110.055 88.987  1.00 27.97  ? 128 THR A CG2 1 
ATOM   888   N N   . TRP A 1 129 ? 152.432 113.544 89.684  1.00 26.34  ? 129 TRP A N   1 
ATOM   889   C CA  . TRP A 1 129 ? 152.038 114.718 88.908  1.00 26.34  ? 129 TRP A CA  1 
ATOM   890   C C   . TRP A 1 129 ? 152.453 114.469 87.462  1.00 26.34  ? 129 TRP A C   1 
ATOM   891   O O   . TRP A 1 129 ? 153.631 114.601 87.114  1.00 26.34  ? 129 TRP A O   1 
ATOM   892   C CB  . TRP A 1 129 ? 152.675 115.984 89.472  1.00 26.34  ? 129 TRP A CB  1 
ATOM   893   C CG  . TRP A 1 129 ? 152.568 116.087 90.962  1.00 26.34  ? 129 TRP A CG  1 
ATOM   894   C CD1 . TRP A 1 129 ? 153.557 115.858 91.871  1.00 26.34  ? 129 TRP A CD1 1 
ATOM   895   C CD2 . TRP A 1 129 ? 151.404 116.440 91.717  1.00 26.34  ? 129 TRP A CD2 1 
ATOM   896   N NE1 . TRP A 1 129 ? 153.083 116.049 93.144  1.00 26.34  ? 129 TRP A NE1 1 
ATOM   897   C CE2 . TRP A 1 129 ? 151.763 116.406 93.077  1.00 26.34  ? 129 TRP A CE2 1 
ATOM   898   C CE3 . TRP A 1 129 ? 150.093 116.781 91.374  1.00 26.34  ? 129 TRP A CE3 1 
ATOM   899   C CZ2 . TRP A 1 129 ? 150.859 116.699 94.094  1.00 26.34  ? 129 TRP A CZ2 1 
ATOM   900   C CZ3 . TRP A 1 129 ? 149.199 117.074 92.385  1.00 26.34  ? 129 TRP A CZ3 1 
ATOM   901   C CH2 . TRP A 1 129 ? 149.586 117.032 93.728  1.00 26.34  ? 129 TRP A CH2 1 
ATOM   902   N N   . ALA A 1 130 ? 151.486 114.112 86.622  1.00 30.52  ? 130 ALA A N   1 
ATOM   903   C CA  . ALA A 1 130 ? 151.758 113.702 85.252  1.00 30.52  ? 130 ALA A CA  1 
ATOM   904   C C   . ALA A 1 130 ? 151.598 114.880 84.300  1.00 30.52  ? 130 ALA A C   1 
ATOM   905   O O   . ALA A 1 130 ? 150.605 115.611 84.365  1.00 30.52  ? 130 ALA A O   1 
ATOM   906   C CB  . ALA A 1 130 ? 150.826 112.563 84.840  1.00 30.52  ? 130 ALA A CB  1 
ATOM   907   N N   . GLY A 1 131 ? 152.577 115.056 83.416  1.00 30.33  ? 131 GLY A N   1 
ATOM   908   C CA  . GLY A 1 131 ? 152.525 116.091 82.406  1.00 30.33  ? 131 GLY A CA  1 
ATOM   909   C C   . GLY A 1 131 ? 153.085 117.434 82.812  1.00 30.33  ? 131 GLY A C   1 
ATOM   910   O O   . GLY A 1 131 ? 152.961 118.392 82.040  1.00 30.33  ? 131 GLY A O   1 
ATOM   911   N N   . VAL A 1 132 ? 153.698 117.540 83.990  1.00 29.20  ? 132 VAL A N   1 
ATOM   912   C CA  . VAL A 1 132 ? 154.267 118.789 84.475  1.00 29.20  ? 132 VAL A CA  1 
ATOM   913   C C   . VAL A 1 132 ? 155.697 118.531 84.933  1.00 29.20  ? 132 VAL A C   1 
ATOM   914   O O   . VAL A 1 132 ? 156.127 117.389 85.094  1.00 29.20  ? 132 VAL A O   1 
ATOM   915   C CB  . VAL A 1 132 ? 153.438 119.408 85.619  1.00 29.20  ? 132 VAL A CB  1 
ATOM   916   C CG1 . VAL A 1 132 ? 152.079 119.857 85.110  1.00 29.20  ? 132 VAL A CG1 1 
ATOM   917   C CG2 . VAL A 1 132 ? 153.287 118.418 86.760  1.00 29.20  ? 132 VAL A CG2 1 
ATOM   918   N N   . SER A 1 133 ? 156.433 119.618 85.136  1.00 28.58  ? 133 SER A N   1 
ATOM   919   C CA  . SER A 1 133 ? 157.788 119.562 85.664  1.00 28.58  ? 133 SER A CA  1 
ATOM   920   C C   . SER A 1 133 ? 157.783 119.929 87.142  1.00 28.58  ? 133 SER A C   1 
ATOM   921   O O   . SER A 1 133 ? 157.015 120.786 87.585  1.00 28.58  ? 133 SER A O   1 
ATOM   922   C CB  . SER A 1 133 ? 158.717 120.501 84.893  1.00 28.58  ? 133 SER A CB  1 
ATOM   923   O OG  . SER A 1 133 ? 158.158 121.795 84.785  1.00 28.58  ? 133 SER A OG  1 
ATOM   924   N N   . GLN A 1 134 ? 158.650 119.270 87.903  1.00 27.43  ? 134 GLN A N   1 
ATOM   925   C CA  . GLN A 1 134 ? 158.675 119.391 89.352  1.00 27.43  ? 134 GLN A CA  1 
ATOM   926   C C   . GLN A 1 134 ? 159.975 120.034 89.816  1.00 27.43  ? 134 GLN A C   1 
ATOM   927   O O   . GLN A 1 134 ? 160.903 120.259 89.035  1.00 27.43  ? 134 GLN A O   1 
ATOM   928   C CB  . GLN A 1 134 ? 158.503 118.020 90.016  1.00 27.43  ? 134 GLN A CB  1 
ATOM   929   C CG  . GLN A 1 134 ? 157.497 117.117 89.328  1.00 27.43  ? 134 GLN A CG  1 
ATOM   930   C CD  . GLN A 1 134 ? 157.238 115.843 90.100  1.00 27.43  ? 134 GLN A CD  1 
ATOM   931   O OE1 . GLN A 1 134 ? 157.668 115.698 91.243  1.00 27.43  ? 134 GLN A OE1 1 
ATOM   932   N NE2 . GLN A 1 134 ? 156.531 114.909 89.478  1.00 27.43  ? 134 GLN A NE2 1 
ATOM   933   N N   . ASN A 1 135 ? 160.018 120.334 91.115  1.00 26.89  ? 135 ASN A N   1 
ATOM   934   C CA  . ASN A 1 135 ? 161.218 120.813 91.802  1.00 26.89  ? 135 ASN A CA  1 
ATOM   935   C C   . ASN A 1 135 ? 161.715 122.136 91.215  1.00 26.89  ? 135 ASN A C   1 
ATOM   936   O O   . ASN A 1 135 ? 162.857 122.265 90.771  1.00 26.89  ? 135 ASN A O   1 
ATOM   937   C CB  . ASN A 1 135 ? 162.320 119.747 91.781  1.00 26.89  ? 135 ASN A CB  1 
ATOM   938   C CG  . ASN A 1 135 ? 161.908 118.470 92.484  1.00 26.89  ? 135 ASN A CG  1 
ATOM   939   O OD1 . ASN A 1 135 ? 161.518 118.488 93.651  1.00 26.89  ? 135 ASN A OD1 1 
ATOM   940   N ND2 . ASN A 1 135 ? 161.992 117.351 91.777  1.00 26.89  ? 135 ASN A ND2 1 
ATOM   941   N N   . GLY A 1 136 ? 160.829 123.130 91.229  1.00 26.76  ? 136 GLY A N   1 
ATOM   942   C CA  . GLY A 1 136 ? 161.214 124.465 90.817  1.00 26.76  ? 136 GLY A CA  1 
ATOM   943   C C   . GLY A 1 136 ? 161.858 125.245 91.949  1.00 26.76  ? 136 GLY A C   1 
ATOM   944   O O   . GLY A 1 136 ? 161.596 125.013 93.128  1.00 26.76  ? 136 GLY A O   1 
ATOM   945   N N   . GLY A 1 137 ? 162.718 126.194 91.574  1.00 28.37  ? 137 GLY A N   1 
ATOM   946   C CA  . GLY A 1 137 ? 163.460 126.976 92.540  1.00 28.37  ? 137 GLY A CA  1 
ATOM   947   C C   . GLY A 1 137 ? 163.577 128.425 92.111  1.00 28.37  ? 137 GLY A C   1 
ATOM   948   O O   . GLY A 1 137 ? 163.109 128.817 91.042  1.00 28.37  ? 137 GLY A O   1 
ATOM   949   N N   . SER A 1 138 ? 164.215 129.214 92.972  1.00 29.65  ? 138 SER A N   1 
ATOM   950   C CA  . SER A 1 138 ? 164.398 130.636 92.725  1.00 29.65  ? 138 SER A CA  1 
ATOM   951   C C   . SER A 1 138 ? 165.692 131.093 93.380  1.00 29.65  ? 138 SER A C   1 
ATOM   952   O O   . SER A 1 138 ? 166.212 130.446 94.292  1.00 29.65  ? 138 SER A O   1 
ATOM   953   C CB  . SER A 1 138 ? 163.213 131.455 93.250  1.00 29.65  ? 138 SER A CB  1 
ATOM   954   O OG  . SER A 1 138 ? 163.305 132.807 92.837  1.00 29.65  ? 138 SER A OG  1 
ATOM   955   N N   . SER A 1 139 ? 166.211 132.224 92.898  1.00 29.46  ? 139 SER A N   1 
ATOM   956   C CA  . SER A 1 139 ? 167.429 132.790 93.463  1.00 29.46  ? 139 SER A CA  1 
ATOM   957   C C   . SER A 1 139 ? 167.187 133.485 94.795  1.00 29.46  ? 139 SER A C   1 
ATOM   958   O O   . SER A 1 139 ? 168.148 133.741 95.528  1.00 29.46  ? 139 SER A O   1 
ATOM   959   C CB  . SER A 1 139 ? 168.061 133.774 92.477  1.00 29.46  ? 139 SER A CB  1 
ATOM   960   O OG  . SER A 1 139 ? 167.239 134.913 92.295  1.00 29.46  ? 139 SER A OG  1 
ATOM   961   N N   . ALA A 1 140 ? 165.933 133.797 95.122  1.00 29.22  ? 140 ALA A N   1 
ATOM   962   C CA  . ALA A 1 140 ? 165.610 134.376 96.419  1.00 29.22  ? 140 ALA A CA  1 
ATOM   963   C C   . ALA A 1 140 ? 165.720 133.369 97.553  1.00 29.22  ? 140 ALA A C   1 
ATOM   964   O O   . ALA A 1 140 ? 165.675 133.769 98.720  1.00 29.22  ? 140 ALA A O   1 
ATOM   965   C CB  . ALA A 1 140 ? 164.201 134.969 96.394  1.00 29.22  ? 140 ALA A CB  1 
ATOM   966   N N   . CYS A 1 141 ? 165.864 132.083 97.240  1.00 30.71  ? 141 CYS A N   1 
ATOM   967   C CA  . CYS A 1 141 ? 165.944 131.020 98.238  1.00 30.71  ? 141 CYS A CA  1 
ATOM   968   C C   . CYS A 1 141 ? 167.078 130.094 97.805  1.00 30.71  ? 141 CYS A C   1 
ATOM   969   O O   . CYS A 1 141 ? 166.861 129.160 97.029  1.00 30.71  ? 141 CYS A O   1 
ATOM   970   C CB  . CYS A 1 141 ? 164.614 130.280 98.346  1.00 30.71  ? 141 CYS A CB  1 
ATOM   971   S SG  . CYS A 1 141 ? 164.414 129.252 99.812  1.00 30.71  ? 141 CYS A SG  1 
ATOM   972   N N   . LYS A 1 142 ? 168.285 130.356 98.298  1.00 33.03  ? 142 LYS A N   1 
ATOM   973   C CA  . LYS A 1 142 ? 169.486 129.655 97.860  1.00 33.03  ? 142 LYS A CA  1 
ATOM   974   C C   . LYS A 1 142 ? 169.803 128.517 98.822  1.00 33.03  ? 142 LYS A C   1 
ATOM   975   O O   . LYS A 1 142 ? 169.899 128.732 100.035 1.00 33.03  ? 142 LYS A O   1 
ATOM   976   C CB  . LYS A 1 142 ? 170.674 130.613 97.768  1.00 33.03  ? 142 LYS A CB  1 
ATOM   977   C CG  . LYS A 1 142 ? 170.467 131.783 96.824  1.00 33.03  ? 142 LYS A CG  1 
ATOM   978   C CD  . LYS A 1 142 ? 170.456 131.327 95.378  1.00 33.03  ? 142 LYS A CD  1 
ATOM   979   C CE  . LYS A 1 142 ? 171.849 130.951 94.911  1.00 33.03  ? 142 LYS A CE  1 
ATOM   980   N NZ  . LYS A 1 142 ? 172.753 132.132 94.868  1.00 33.03  ? 142 LYS A NZ  1 
ATOM   981   N N   . ARG A 1 143 ? 169.972 127.316 98.279  1.00 31.80  ? 143 ARG A N   1 
ATOM   982   C CA  . ARG A 1 143 ? 170.413 126.145 99.033  1.00 31.80  ? 143 ARG A CA  1 
ATOM   983   C C   . ARG A 1 143 ? 171.848 125.858 98.601  1.00 31.80  ? 143 ARG A C   1 
ATOM   984   O O   . ARG A 1 143 ? 172.093 125.054 97.701  1.00 31.80  ? 143 ARG A O   1 
ATOM   985   C CB  . ARG A 1 143 ? 169.498 124.952 98.789  1.00 31.80  ? 143 ARG A CB  1 
ATOM   986   C CG  . ARG A 1 143 ? 168.152 125.067 99.471  1.00 31.80  ? 143 ARG A CG  1 
ATOM   987   C CD  . ARG A 1 143 ? 167.355 123.782 99.361  1.00 31.80  ? 143 ARG A CD  1 
ATOM   988   N NE  . ARG A 1 143 ? 166.112 123.864 100.116 1.00 31.80  ? 143 ARG A NE  1 
ATOM   989   C CZ  . ARG A 1 143 ? 166.010 123.621 101.414 1.00 31.80  ? 143 ARG A CZ  1 
ATOM   990   N NH1 . ARG A 1 143 ? 167.058 123.251 102.132 1.00 31.80  ? 143 ARG A NH1 1 
ATOM   991   N NH2 . ARG A 1 143 ? 164.829 123.754 102.009 1.00 31.80  ? 143 ARG A NH2 1 
ATOM   992   N N   . GLY A 1 144 ? 172.797 126.519 99.255  1.00 34.58  ? 144 GLY A N   1 
ATOM   993   C CA  . GLY A 1 144 ? 174.176 126.473 98.837  1.00 34.58  ? 144 GLY A CA  1 
ATOM   994   C C   . GLY A 1 144 ? 174.434 127.460 97.718  1.00 34.58  ? 144 GLY A C   1 
ATOM   995   O O   . GLY A 1 144 ? 174.031 128.626 97.782  1.00 34.58  ? 144 GLY A O   1 
ATOM   996   N N   . PRO A 1 145 ? 175.122 127.012 96.664  1.00 36.89  ? 145 PRO A N   1 
ATOM   997   C CA  . PRO A 1 145 ? 175.333 127.881 95.499  1.00 36.89  ? 145 PRO A CA  1 
ATOM   998   C C   . PRO A 1 145 ? 174.236 127.788 94.451  1.00 36.89  ? 145 PRO A C   1 
ATOM   999   O O   . PRO A 1 145 ? 174.274 128.552 93.476  1.00 36.89  ? 145 PRO A O   1 
ATOM   1000  C CB  . PRO A 1 145 ? 176.672 127.387 94.934  1.00 36.89  ? 145 PRO A CB  1 
ATOM   1001  C CG  . PRO A 1 145 ? 176.819 125.973 95.432  1.00 36.89  ? 145 PRO A CG  1 
ATOM   1002  C CD  . PRO A 1 145 ? 175.829 125.727 96.540  1.00 36.89  ? 145 PRO A CD  1 
ATOM   1003  N N   . ALA A 1 146 ? 173.269 126.892 94.616  1.00 34.73  ? 146 ALA A N   1 
ATOM   1004  C CA  . ALA A 1 146 ? 172.222 126.690 93.628  1.00 34.73  ? 146 ALA A CA  1 
ATOM   1005  C C   . ALA A 1 146 ? 170.890 127.253 94.114  1.00 34.73  ? 146 ALA A C   1 
ATOM   1006  O O   . ALA A 1 146 ? 170.682 127.492 95.306  1.00 34.73  ? 146 ALA A O   1 
ATOM   1007  C CB  . ALA A 1 146 ? 172.072 125.204 93.302  1.00 34.73  ? 146 ALA A CB  1 
ATOM   1008  N N   . ASN A 1 147 ? 169.984 127.468 93.163  1.00 33.29  ? 147 ASN A N   1 
ATOM   1009  C CA  . ASN A 1 147 ? 168.642 127.929 93.488  1.00 33.29  ? 147 ASN A CA  1 
ATOM   1010  C C   . ASN A 1 147 ? 167.861 126.831 94.198  1.00 33.29  ? 147 ASN A C   1 
ATOM   1011  O O   . ASN A 1 147 ? 167.970 125.650 93.860  1.00 33.29  ? 147 ASN A O   1 
ATOM   1012  C CB  . ASN A 1 147 ? 167.906 128.356 92.219  1.00 33.29  ? 147 ASN A CB  1 
ATOM   1013  C CG  . ASN A 1 147 ? 168.564 129.532 91.531  1.00 33.29  ? 147 ASN A CG  1 
ATOM   1014  O OD1 . ASN A 1 147 ? 169.547 130.083 92.024  1.00 33.29  ? 147 ASN A OD1 1 
ATOM   1015  N ND2 . ASN A 1 147 ? 168.024 129.925 90.384  1.00 33.29  ? 147 ASN A ND2 1 
ATOM   1016  N N   . GLY A 1 148 ? 167.064 127.227 95.186  1.00 28.08  ? 148 GLY A N   1 
ATOM   1017  C CA  . GLY A 1 148 ? 166.294 126.265 95.948  1.00 28.08  ? 148 GLY A CA  1 
ATOM   1018  C C   . GLY A 1 148 ? 164.871 126.698 96.229  1.00 28.08  ? 148 GLY A C   1 
ATOM   1019  O O   . GLY A 1 148 ? 164.369 127.654 95.631  1.00 28.08  ? 148 GLY A O   1 
ATOM   1020  N N   . PHE A 1 149 ? 164.215 125.995 97.145  1.00 23.28  ? 149 PHE A N   1 
ATOM   1021  C CA  . PHE A 1 149 ? 162.833 126.268 97.513  1.00 23.28  ? 149 PHE A CA  1 
ATOM   1022  C C   . PHE A 1 149 ? 162.599 125.668 98.893  1.00 23.28  ? 149 PHE A C   1 
ATOM   1023  O O   . PHE A 1 149 ? 163.510 125.106 99.507  1.00 23.28  ? 149 PHE A O   1 
ATOM   1024  C CB  . PHE A 1 149 ? 161.865 125.700 96.469  1.00 23.28  ? 149 PHE A CB  1 
ATOM   1025  C CG  . PHE A 1 149 ? 160.505 126.341 96.480  1.00 23.28  ? 149 PHE A CG  1 
ATOM   1026  C CD1 . PHE A 1 149 ? 160.356 127.688 96.201  1.00 23.28  ? 149 PHE A CD1 1 
ATOM   1027  C CD2 . PHE A 1 149 ? 159.376 125.592 96.762  1.00 23.28  ? 149 PHE A CD2 1 
ATOM   1028  C CE1 . PHE A 1 149 ? 159.108 128.275 96.207  1.00 23.28  ? 149 PHE A CE1 1 
ATOM   1029  C CE2 . PHE A 1 149 ? 158.125 126.173 96.771  1.00 23.28  ? 149 PHE A CE2 1 
ATOM   1030  C CZ  . PHE A 1 149 ? 157.991 127.517 96.493  1.00 23.28  ? 149 PHE A CZ  1 
ATOM   1031  N N   . PHE A 1 150 ? 161.370 125.800 99.386  1.00 22.28  ? 150 PHE A N   1 
ATOM   1032  C CA  . PHE A 1 150 ? 161.000 125.142 100.630 1.00 22.28  ? 150 PHE A CA  1 
ATOM   1033  C C   . PHE A 1 150 ? 161.106 123.631 100.471 1.00 22.28  ? 150 PHE A C   1 
ATOM   1034  O O   . PHE A 1 150 ? 160.715 123.070 99.444  1.00 22.28  ? 150 PHE A O   1 
ATOM   1035  C CB  . PHE A 1 150 ? 159.580 125.533 101.039 1.00 22.28  ? 150 PHE A CB  1 
ATOM   1036  C CG  . PHE A 1 150 ? 159.397 127.005 101.265 1.00 22.28  ? 150 PHE A CG  1 
ATOM   1037  C CD1 . PHE A 1 150 ? 159.800 127.592 102.452 1.00 22.28  ? 150 PHE A CD1 1 
ATOM   1038  C CD2 . PHE A 1 150 ? 158.816 127.802 100.294 1.00 22.28  ? 150 PHE A CD2 1 
ATOM   1039  C CE1 . PHE A 1 150 ? 159.630 128.944 102.664 1.00 22.28  ? 150 PHE A CE1 1 
ATOM   1040  C CE2 . PHE A 1 150 ? 158.643 129.156 100.500 1.00 22.28  ? 150 PHE A CE2 1 
ATOM   1041  C CZ  . PHE A 1 150 ? 159.050 129.727 101.686 1.00 22.28  ? 150 PHE A CZ  1 
ATOM   1042  N N   . SER A 1 151 ? 161.644 122.970 101.495 1.00 23.03  ? 151 SER A N   1 
ATOM   1043  C CA  . SER A 1 151 ? 161.902 121.539 101.405 1.00 23.03  ? 151 SER A CA  1 
ATOM   1044  C C   . SER A 1 151 ? 160.642 120.696 101.539 1.00 23.03  ? 151 SER A C   1 
ATOM   1045  O O   . SER A 1 151 ? 160.658 119.523 101.153 1.00 23.03  ? 151 SER A O   1 
ATOM   1046  C CB  . SER A 1 151 ? 162.919 121.119 102.469 1.00 23.03  ? 151 SER A CB  1 
ATOM   1047  O OG  . SER A 1 151 ? 162.336 121.096 103.759 1.00 23.03  ? 151 SER A OG  1 
ATOM   1048  N N   . ARG A 1 152 ? 159.557 121.259 102.067 1.00 21.68  ? 152 ARG A N   1 
ATOM   1049  C CA  . ARG A 1 152 ? 158.315 120.524 102.263 1.00 21.68  ? 152 ARG A CA  1 
ATOM   1050  C C   . ARG A 1 152 ? 157.265 120.843 101.208 1.00 21.68  ? 152 ARG A C   1 
ATOM   1051  O O   . ARG A 1 152 ? 156.126 120.382 101.326 1.00 21.68  ? 152 ARG A O   1 
ATOM   1052  C CB  . ARG A 1 152 ? 157.753 120.803 103.658 1.00 21.68  ? 152 ARG A CB  1 
ATOM   1053  C CG  . ARG A 1 152 ? 158.705 120.466 104.792 1.00 21.68  ? 152 ARG A CG  1 
ATOM   1054  C CD  . ARG A 1 152 ? 159.230 119.050 104.669 1.00 21.68  ? 152 ARG A CD  1 
ATOM   1055  N NE  . ARG A 1 152 ? 159.819 118.574 105.913 1.00 21.68  ? 152 ARG A NE  1 
ATOM   1056  C CZ  . ARG A 1 152 ? 160.691 117.579 105.995 1.00 21.68  ? 152 ARG A CZ  1 
ATOM   1057  N NH1 . ARG A 1 152 ? 161.110 116.937 104.918 1.00 21.68  ? 152 ARG A NH1 1 
ATOM   1058  N NH2 . ARG A 1 152 ? 161.155 117.218 107.188 1.00 21.68  ? 152 ARG A NH2 1 
ATOM   1059  N N   . LEU A 1 153 ? 157.618 121.612 100.182 1.00 20.93  ? 153 LEU A N   1 
ATOM   1060  C CA  . LEU A 1 153 ? 156.685 122.009 99.140  1.00 20.93  ? 153 LEU A CA  1 
ATOM   1061  C C   . LEU A 1 153 ? 157.292 121.727 97.773  1.00 20.93  ? 153 LEU A C   1 
ATOM   1062  O O   . LEU A 1 153 ? 158.514 121.669 97.613  1.00 20.93  ? 153 LEU A O   1 
ATOM   1063  C CB  . LEU A 1 153 ? 156.311 123.492 99.258  1.00 20.93  ? 153 LEU A CB  1 
ATOM   1064  C CG  . LEU A 1 153 ? 155.497 123.881 100.493 1.00 20.93  ? 153 LEU A CG  1 
ATOM   1065  C CD1 . LEU A 1 153 ? 155.614 125.368 100.769 1.00 20.93  ? 153 LEU A CD1 1 
ATOM   1066  C CD2 . LEU A 1 153 ? 154.043 123.480 100.324 1.00 20.93  ? 153 LEU A CD2 1 
ATOM   1067  N N   . ASN A 1 154 ? 156.420 121.550 96.783  1.00 22.71  ? 154 ASN A N   1 
ATOM   1068  C CA  . ASN A 1 154 ? 156.820 121.221 95.420  1.00 22.71  ? 154 ASN A CA  1 
ATOM   1069  C C   . ASN A 1 154 ? 156.246 122.260 94.467  1.00 22.71  ? 154 ASN A C   1 
ATOM   1070  O O   . ASN A 1 154 ? 155.027 122.454 94.417  1.00 22.71  ? 154 ASN A O   1 
ATOM   1071  C CB  . ASN A 1 154 ? 156.347 119.816 95.042  1.00 22.71  ? 154 ASN A CB  1 
ATOM   1072  C CG  . ASN A 1 154 ? 157.099 119.243 93.861  1.00 22.71  ? 154 ASN A CG  1 
ATOM   1073  O OD1 . ASN A 1 154 ? 157.916 119.920 93.242  1.00 22.71  ? 154 ASN A OD1 1 
ATOM   1074  N ND2 . ASN A 1 154 ? 156.830 117.985 93.545  1.00 22.71  ? 154 ASN A ND2 1 
ATOM   1075  N N   . TRP A 1 155 ? 157.121 122.919 93.711  1.00 25.56  ? 155 TRP A N   1 
ATOM   1076  C CA  . TRP A 1 155 ? 156.716 123.931 92.741  1.00 25.56  ? 155 TRP A CA  1 
ATOM   1077  C C   . TRP A 1 155 ? 156.566 123.266 91.377  1.00 25.56  ? 155 TRP A C   1 
ATOM   1078  O O   . TRP A 1 155 ? 157.548 122.789 90.799  1.00 25.56  ? 155 TRP A O   1 
ATOM   1079  C CB  . TRP A 1 155 ? 157.738 125.064 92.694  1.00 25.56  ? 155 TRP A CB  1 
ATOM   1080  C CG  . TRP A 1 155 ? 157.238 126.324 92.052  1.00 25.56  ? 155 TRP A CG  1 
ATOM   1081  C CD1 . TRP A 1 155 ? 156.094 126.478 91.327  1.00 25.56  ? 155 TRP A CD1 1 
ATOM   1082  C CD2 . TRP A 1 155 ? 157.871 127.608 92.079  1.00 25.56  ? 155 TRP A CD2 1 
ATOM   1083  N NE1 . TRP A 1 155 ? 155.975 127.777 90.900  1.00 25.56  ? 155 TRP A NE1 1 
ATOM   1084  C CE2 . TRP A 1 155 ? 157.053 128.492 91.350  1.00 25.56  ? 155 TRP A CE2 1 
ATOM   1085  C CE3 . TRP A 1 155 ? 159.049 128.096 92.650  1.00 25.56  ? 155 TRP A CE3 1 
ATOM   1086  C CZ2 . TRP A 1 155 ? 157.376 129.835 91.176  1.00 25.56  ? 155 TRP A CZ2 1 
ATOM   1087  C CZ3 . TRP A 1 155 ? 159.367 129.430 92.476  1.00 25.56  ? 155 TRP A CZ3 1 
ATOM   1088  C CH2 . TRP A 1 155 ? 158.534 130.283 91.746  1.00 25.56  ? 155 TRP A CH2 1 
ATOM   1089  N N   . LEU A 1 156 ? 155.341 123.240 90.859  1.00 26.04  ? 156 LEU A N   1 
ATOM   1090  C CA  . LEU A 1 156 ? 155.029 122.597 89.590  1.00 26.04  ? 156 LEU A CA  1 
ATOM   1091  C C   . LEU A 1 156 ? 154.795 123.656 88.521  1.00 26.04  ? 156 LEU A C   1 
ATOM   1092  O O   . LEU A 1 156 ? 154.031 124.602 88.737  1.00 26.04  ? 156 LEU A O   1 
ATOM   1093  C CB  . LEU A 1 156 ? 153.794 121.702 89.717  1.00 26.04  ? 156 LEU A CB  1 
ATOM   1094  C CG  . LEU A 1 156 ? 153.714 120.760 90.919  1.00 26.04  ? 156 LEU A CG  1 
ATOM   1095  C CD1 . LEU A 1 156 ? 152.315 120.190 91.040  1.00 26.04  ? 156 LEU A CD1 1 
ATOM   1096  C CD2 . LEU A 1 156 ? 154.737 119.647 90.803  1.00 26.04  ? 156 LEU A CD2 1 
ATOM   1097  N N   . THR A 1 157 ? 155.450 123.493 87.375  1.00 28.29  ? 157 THR A N   1 
ATOM   1098  C CA  . THR A 1 157 ? 155.277 124.373 86.228  1.00 28.29  ? 157 THR A CA  1 
ATOM   1099  C C   . THR A 1 157 ? 154.985 123.527 84.994  1.00 28.29  ? 157 THR A C   1 
ATOM   1100  O O   . THR A 1 157 ? 154.861 122.302 85.068  1.00 28.29  ? 157 THR A O   1 
ATOM   1101  C CB  . THR A 1 157 ? 156.510 125.261 86.003  1.00 28.29  ? 157 THR A CB  1 
ATOM   1102  O OG1 . THR A 1 157 ? 157.687 124.448 85.935  1.00 28.29  ? 157 THR A OG1 1 
ATOM   1103  C CG2 . THR A 1 157 ? 156.659 126.268 87.132  1.00 28.29  ? 157 THR A CG2 1 
ATOM   1104  N N   . LYS A 1 158 ? 154.872 124.192 83.849  1.00 30.48  ? 158 LYS A N   1 
ATOM   1105  C CA  . LYS A 1 158 ? 154.557 123.501 82.608  1.00 30.48  ? 158 LYS A CA  1 
ATOM   1106  C C   . LYS A 1 158 ? 155.724 122.630 82.156  1.00 30.48  ? 158 LYS A C   1 
ATOM   1107  O O   . LYS A 1 158 ? 156.884 122.876 82.496  1.00 30.48  ? 158 LYS A O   1 
ATOM   1108  C CB  . LYS A 1 158 ? 154.201 124.506 81.513  1.00 30.48  ? 158 LYS A CB  1 
ATOM   1109  C CG  . LYS A 1 158 ? 155.405 125.145 80.844  1.00 30.48  ? 158 LYS A CG  1 
ATOM   1110  C CD  . LYS A 1 158 ? 154.999 125.995 79.656  1.00 30.48  ? 158 LYS A CD  1 
ATOM   1111  C CE  . LYS A 1 158 ? 156.196 126.732 79.081  1.00 30.48  ? 158 LYS A CE  1 
ATOM   1112  N NZ  . LYS A 1 158 ? 155.802 127.672 77.999  1.00 30.48  ? 158 LYS A NZ  1 
ATOM   1113  N N   . SER A 1 159 ? 155.401 121.593 81.388  1.00 32.66  ? 159 SER A N   1 
ATOM   1114  C CA  . SER A 1 159 ? 156.392 120.707 80.792  1.00 32.66  ? 159 SER A CA  1 
ATOM   1115  C C   . SER A 1 159 ? 156.288 120.827 79.280  1.00 32.66  ? 159 SER A C   1 
ATOM   1116  O O   . SER A 1 159 ? 155.277 120.431 78.691  1.00 32.66  ? 159 SER A O   1 
ATOM   1117  C CB  . SER A 1 159 ? 156.180 119.258 81.235  1.00 32.66  ? 159 SER A CB  1 
ATOM   1118  O OG  . SER A 1 159 ? 157.218 118.423 80.753  1.00 32.66  ? 159 SER A OG  1 
ATOM   1119  N N   . GLY A 1 160 ? 157.329 121.368 78.655  1.00 34.66  ? 160 GLY A N   1 
ATOM   1120  C CA  . GLY A 1 160 ? 157.285 121.612 77.229  1.00 34.66  ? 160 GLY A CA  1 
ATOM   1121  C C   . GLY A 1 160 ? 156.477 122.849 76.903  1.00 34.66  ? 160 GLY A C   1 
ATOM   1122  O O   . GLY A 1 160 ? 156.946 123.974 77.095  1.00 34.66  ? 160 GLY A O   1 
ATOM   1123  N N   . SER A 1 161 ? 155.254 122.653 76.403  1.00 35.01  ? 161 SER A N   1 
ATOM   1124  C CA  . SER A 1 161 ? 154.372 123.776 76.111  1.00 35.01  ? 161 SER A CA  1 
ATOM   1125  C C   . SER A 1 161 ? 152.939 123.520 76.568  1.00 35.01  ? 161 SER A C   1 
ATOM   1126  O O   . SER A 1 161 ? 152.009 124.127 76.023  1.00 35.01  ? 161 SER A O   1 
ATOM   1127  C CB  . SER A 1 161 ? 154.383 124.099 74.615  1.00 35.01  ? 161 SER A CB  1 
ATOM   1128  O OG  . SER A 1 161 ? 153.448 123.298 73.915  1.00 35.01  ? 161 SER A OG  1 
ATOM   1129  N N   . SER A 1 162 ? 152.731 122.644 77.550  1.00 32.16  ? 162 SER A N   1 
ATOM   1130  C CA  . SER A 1 162 ? 151.392 122.306 78.006  1.00 32.16  ? 162 SER A CA  1 
ATOM   1131  C C   . SER A 1 162 ? 151.380 122.156 79.519  1.00 32.16  ? 162 SER A C   1 
ATOM   1132  O O   . SER A 1 162 ? 152.383 121.783 80.133  1.00 32.16  ? 162 SER A O   1 
ATOM   1133  C CB  . SER A 1 162 ? 150.884 121.015 77.352  1.00 32.16  ? 162 SER A CB  1 
ATOM   1134  O OG  . SER A 1 162 ? 151.658 119.901 77.759  1.00 32.16  ? 162 SER A OG  1 
ATOM   1135  N N   . TYR A 1 163 ? 150.226 122.452 80.112  1.00 28.14  ? 163 TYR A N   1 
ATOM   1136  C CA  . TYR A 1 163 ? 149.990 122.268 81.543  1.00 28.14  ? 163 TYR A CA  1 
ATOM   1137  C C   . TYR A 1 163 ? 148.632 121.596 81.689  1.00 28.14  ? 163 TYR A C   1 
ATOM   1138  O O   . TYR A 1 163 ? 147.593 122.279 81.674  1.00 28.14  ? 163 TYR A O   1 
ATOM   1139  C CB  . TYR A 1 163 ? 150.035 123.597 82.291  1.00 28.14  ? 163 TYR A CB  1 
ATOM   1140  C CG  . TYR A 1 163 ? 150.113 123.479 83.801  1.00 28.14  ? 163 TYR A CG  1 
ATOM   1141  C CD1 . TYR A 1 163 ? 149.023 123.048 84.545  1.00 28.14  ? 163 TYR A CD1 1 
ATOM   1142  C CD2 . TYR A 1 163 ? 151.275 123.814 84.481  1.00 28.14  ? 163 TYR A CD2 1 
ATOM   1143  C CE1 . TYR A 1 163 ? 149.093 122.944 85.920  1.00 28.14  ? 163 TYR A CE1 1 
ATOM   1144  C CE2 . TYR A 1 163 ? 151.352 123.715 85.855  1.00 28.14  ? 163 TYR A CE2 1 
ATOM   1145  C CZ  . TYR A 1 163 ? 150.259 123.280 86.570  1.00 28.14  ? 163 TYR A CZ  1 
ATOM   1146  O OH  . TYR A 1 163 ? 150.332 123.180 87.939  1.00 28.14  ? 163 TYR A OH  1 
ATOM   1147  N N   . PRO A 1 164 ? 148.592 120.274 81.826  1.00 28.85  ? 164 PRO A N   1 
ATOM   1148  C CA  . PRO A 1 164 ? 147.305 119.570 81.852  1.00 28.85  ? 164 PRO A CA  1 
ATOM   1149  C C   . PRO A 1 164 ? 146.587 119.771 83.178  1.00 28.85  ? 164 PRO A C   1 
ATOM   1150  O O   . PRO A 1 164 ? 147.098 120.377 84.121  1.00 28.85  ? 164 PRO A O   1 
ATOM   1151  C CB  . PRO A 1 164 ? 147.689 118.100 81.645  1.00 28.85  ? 164 PRO A CB  1 
ATOM   1152  C CG  . PRO A 1 164 ? 149.174 118.092 81.362  1.00 28.85  ? 164 PRO A CG  1 
ATOM   1153  C CD  . PRO A 1 164 ? 149.726 119.347 81.942  1.00 28.85  ? 164 PRO A CD  1 
ATOM   1154  N N   . LEU A 1 165 ? 145.368 119.243 83.234  1.00 25.05  ? 165 LEU A N   1 
ATOM   1155  C CA  . LEU A 1 165 ? 144.580 119.276 84.457  1.00 25.05  ? 165 LEU A CA  1 
ATOM   1156  C C   . LEU A 1 165 ? 145.076 118.201 85.415  1.00 25.05  ? 165 LEU A C   1 
ATOM   1157  O O   . LEU A 1 165 ? 145.202 117.032 85.039  1.00 25.05  ? 165 LEU A O   1 
ATOM   1158  C CB  . LEU A 1 165 ? 143.099 119.070 84.146  1.00 25.05  ? 165 LEU A CB  1 
ATOM   1159  C CG  . LEU A 1 165 ? 142.149 119.003 85.344  1.00 25.05  ? 165 LEU A CG  1 
ATOM   1160  C CD1 . LEU A 1 165 ? 141.832 120.396 85.861  1.00 25.05  ? 165 LEU A CD1 1 
ATOM   1161  C CD2 . LEU A 1 165 ? 140.877 118.261 84.978  1.00 25.05  ? 165 LEU A CD2 1 
ATOM   1162  N N   . LEU A 1 166 ? 145.360 118.599 86.650  1.00 24.73  ? 166 LEU A N   1 
ATOM   1163  C CA  . LEU A 1 166 ? 145.872 117.692 87.667  1.00 24.73  ? 166 LEU A CA  1 
ATOM   1164  C C   . LEU A 1 166 ? 144.721 117.200 88.533  1.00 24.73  ? 166 LEU A C   1 
ATOM   1165  O O   . LEU A 1 166 ? 143.880 117.993 88.966  1.00 24.73  ? 166 LEU A O   1 
ATOM   1166  C CB  . LEU A 1 166 ? 146.930 118.380 88.531  1.00 24.73  ? 166 LEU A CB  1 
ATOM   1167  C CG  . LEU A 1 166 ? 148.120 118.999 87.798  1.00 24.73  ? 166 LEU A CG  1 
ATOM   1168  C CD1 . LEU A 1 166 ? 148.881 119.932 88.720  1.00 24.73  ? 166 LEU A CD1 1 
ATOM   1169  C CD2 . LEU A 1 166 ? 149.038 117.923 87.248  1.00 24.73  ? 166 LEU A CD2 1 
ATOM   1170  N N   . ASN A 1 167 ? 144.690 115.891 88.781  1.00 27.76  ? 167 ASN A N   1 
ATOM   1171  C CA  . ASN A 1 167 ? 143.617 115.277 89.562  1.00 27.76  ? 167 ASN A CA  1 
ATOM   1172  C C   . ASN A 1 167 ? 144.209 114.055 90.260  1.00 27.76  ? 167 ASN A C   1 
ATOM   1173  O O   . ASN A 1 167 ? 144.362 112.999 89.641  1.00 27.76  ? 167 ASN A O   1 
ATOM   1174  C CB  . ASN A 1 167 ? 142.440 114.907 88.668  1.00 27.76  ? 167 ASN A CB  1 
ATOM   1175  C CG  . ASN A 1 167 ? 141.228 114.454 89.453  1.00 27.76  ? 167 ASN A CG  1 
ATOM   1176  O OD1 . ASN A 1 167 ? 140.739 115.166 90.328  1.00 27.76  ? 167 ASN A OD1 1 
ATOM   1177  N ND2 . ASN A 1 167 ? 140.735 113.262 89.141  1.00 27.76  ? 167 ASN A ND2 1 
ATOM   1178  N N   . VAL A 1 168 ? 144.539 114.207 91.544  1.00 26.04  ? 168 VAL A N   1 
ATOM   1179  C CA  . VAL A 1 168 ? 145.185 113.159 92.321  1.00 26.04  ? 168 VAL A CA  1 
ATOM   1180  C C   . VAL A 1 168 ? 144.394 112.930 93.601  1.00 26.04  ? 168 VAL A C   1 
ATOM   1181  O O   . VAL A 1 168 ? 143.604 113.771 94.033  1.00 26.04  ? 168 VAL A O   1 
ATOM   1182  C CB  . VAL A 1 168 ? 146.657 113.493 92.656  1.00 26.04  ? 168 VAL A CB  1 
ATOM   1183  C CG1 . VAL A 1 168 ? 147.416 113.897 91.403  1.00 26.04  ? 168 VAL A CG1 1 
ATOM   1184  C CG2 . VAL A 1 168 ? 146.728 114.589 93.703  1.00 26.04  ? 168 VAL A CG2 1 
ATOM   1185  N N   . THR A 1 169 ? 144.616 111.765 94.207  1.00 27.64  ? 169 THR A N   1 
ATOM   1186  C CA  . THR A 1 169 ? 143.930 111.389 95.434  1.00 27.64  ? 169 THR A CA  1 
ATOM   1187  C C   . THR A 1 169 ? 144.893 110.653 96.356  1.00 27.64  ? 169 THR A C   1 
ATOM   1188  O O   . THR A 1 169 ? 145.882 110.062 95.916  1.00 27.64  ? 169 THR A O   1 
ATOM   1189  C CB  . THR A 1 169 ? 142.693 110.523 95.148  1.00 27.64  ? 169 THR A CB  1 
ATOM   1190  O OG1 . THR A 1 169 ? 141.939 110.348 96.352  1.00 27.64  ? 169 THR A OG1 1 
ATOM   1191  C CG2 . THR A 1 169 ? 143.098 109.162 94.610  1.00 27.64  ? 169 THR A CG2 1 
ATOM   1192  N N   . MET A 1 170 ? 144.593 110.708 97.653  1.00 28.76  ? 170 MET A N   1 
ATOM   1193  C CA  . MET A 1 170 ? 145.359 110.014 98.681  1.00 28.76  ? 170 MET A CA  1 
ATOM   1194  C C   . MET A 1 170 ? 144.479 109.735 99.894  1.00 28.76  ? 170 MET A C   1 
ATOM   1195  O O   . MET A 1 170 ? 144.027 110.673 100.562 1.00 28.76  ? 170 MET A O   1 
ATOM   1196  C CB  . MET A 1 170 ? 146.590 110.828 99.090  1.00 28.76  ? 170 MET A CB  1 
ATOM   1197  C CG  . MET A 1 170 ? 147.679 110.006 99.771  1.00 28.76  ? 170 MET A CG  1 
ATOM   1198  S SD  . MET A 1 170 ? 148.752 109.097 98.644  1.00 28.76  ? 170 MET A SD  1 
ATOM   1199  C CE  . MET A 1 170 ? 149.582 110.432 97.793  1.00 28.76  ? 170 MET A CE  1 
ATOM   1200  N N   . PRO A 1 171 ? 144.215 108.471 100.210 1.00 28.54  ? 171 PRO A N   1 
ATOM   1201  C CA  . PRO A 1 171 ? 143.369 108.144 101.359 1.00 28.54  ? 171 PRO A CA  1 
ATOM   1202  C C   . PRO A 1 171 ? 144.156 108.068 102.661 1.00 28.54  ? 171 PRO A C   1 
ATOM   1203  O O   . PRO A 1 171 ? 145.377 107.906 102.681 1.00 28.54  ? 171 PRO A O   1 
ATOM   1204  C CB  . PRO A 1 171 ? 142.792 106.767 100.993 1.00 28.54  ? 171 PRO A CB  1 
ATOM   1205  C CG  . PRO A 1 171 ? 143.629 106.252 99.844  1.00 28.54  ? 171 PRO A CG  1 
ATOM   1206  C CD  . PRO A 1 171 ? 144.673 107.267 99.501  1.00 28.54  ? 171 PRO A CD  1 
ATOM   1207  N N   . ASN A 1 172 ? 143.418 108.191 103.762 1.00 27.57  ? 172 ASN A N   1 
ATOM   1208  C CA  . ASN A 1 172 ? 143.979 108.113 105.109 1.00 27.57  ? 172 ASN A CA  1 
ATOM   1209  C C   . ASN A 1 172 ? 143.637 106.741 105.679 1.00 27.57  ? 172 ASN A C   1 
ATOM   1210  O O   . ASN A 1 172 ? 142.549 106.536 106.223 1.00 27.57  ? 172 ASN A O   1 
ATOM   1211  C CB  . ASN A 1 172 ? 143.439 109.238 105.987 1.00 27.57  ? 172 ASN A CB  1 
ATOM   1212  C CG  . ASN A 1 172 ? 144.138 109.320 107.331 1.00 27.57  ? 172 ASN A CG  1 
ATOM   1213  O OD1 . ASN A 1 172 ? 145.018 108.520 107.638 1.00 27.57  ? 172 ASN A OD1 1 
ATOM   1214  N ND2 . ASN A 1 172 ? 143.745 110.293 108.140 1.00 27.57  ? 172 ASN A ND2 1 
ATOM   1215  N N   . ASN A 1 173 ? 144.572 105.802 105.556 1.00 31.36  ? 173 ASN A N   1 
ATOM   1216  C CA  . ASN A 1 173 ? 144.386 104.442 106.039 1.00 31.36  ? 173 ASN A CA  1 
ATOM   1217  C C   . ASN A 1 173 ? 144.985 104.225 107.423 1.00 31.36  ? 173 ASN A C   1 
ATOM   1218  O O   . ASN A 1 173 ? 145.027 103.085 107.897 1.00 31.36  ? 173 ASN A O   1 
ATOM   1219  C CB  . ASN A 1 173 ? 144.985 103.444 105.046 1.00 31.36  ? 173 ASN A CB  1 
ATOM   1220  C CG  . ASN A 1 173 ? 144.183 103.346 103.763 1.00 31.36  ? 173 ASN A CG  1 
ATOM   1221  O OD1 . ASN A 1 173 ? 142.953 103.358 103.784 1.00 31.36  ? 173 ASN A OD1 1 
ATOM   1222  N ND2 . ASN A 1 173 ? 144.879 103.247 102.637 1.00 31.36  ? 173 ASN A ND2 1 
ATOM   1223  N N   . TYR A 1 174 ? 145.449 105.285 108.076 1.00 32.78  ? 174 TYR A N   1 
ATOM   1224  C CA  . TYR A 1 174 ? 145.997 105.195 109.420 1.00 32.78  ? 174 TYR A CA  1 
ATOM   1225  C C   . TYR A 1 174 ? 144.882 105.420 110.440 1.00 32.78  ? 174 TYR A C   1 
ATOM   1226  O O   . TYR A 1 174 ? 143.697 105.460 110.100 1.00 32.78  ? 174 TYR A O   1 
ATOM   1227  C CB  . TYR A 1 174 ? 147.132 106.201 109.597 1.00 32.78  ? 174 TYR A CB  1 
ATOM   1228  C CG  . TYR A 1 174 ? 148.257 106.049 108.602 1.00 32.78  ? 174 TYR A CG  1 
ATOM   1229  C CD1 . TYR A 1 174 ? 148.926 104.842 108.458 1.00 32.78  ? 174 TYR A CD1 1 
ATOM   1230  C CD2 . TYR A 1 174 ? 148.653 107.115 107.809 1.00 32.78  ? 174 TYR A CD2 1 
ATOM   1231  C CE1 . TYR A 1 174 ? 149.958 104.701 107.550 1.00 32.78  ? 174 TYR A CE1 1 
ATOM   1232  C CE2 . TYR A 1 174 ? 149.683 106.985 106.899 1.00 32.78  ? 174 TYR A CE2 1 
ATOM   1233  C CZ  . TYR A 1 174 ? 150.332 105.776 106.773 1.00 32.78  ? 174 TYR A CZ  1 
ATOM   1234  O OH  . TYR A 1 174 ? 151.358 105.643 105.867 1.00 32.78  ? 174 TYR A OH  1 
ATOM   1235  N N   . ASN A 1 175 ? 145.255 105.571 111.712 1.00 33.65  ? 175 ASN A N   1 
ATOM   1236  C CA  . ASN A 1 175 ? 144.298 105.850 112.777 1.00 33.65  ? 175 ASN A CA  1 
ATOM   1237  C C   . ASN A 1 175 ? 144.554 107.198 113.446 1.00 33.65  ? 175 ASN A C   1 
ATOM   1238  O O   . ASN A 1 175 ? 144.045 107.449 114.543 1.00 33.65  ? 175 ASN A O   1 
ATOM   1239  C CB  . ASN A 1 175 ? 144.290 104.702 113.796 1.00 33.65  ? 175 ASN A CB  1 
ATOM   1240  C CG  . ASN A 1 175 ? 145.530 104.668 114.691 1.00 33.65  ? 175 ASN A CG  1 
ATOM   1241  O OD1 . ASN A 1 175 ? 145.891 105.648 115.342 1.00 33.65  ? 175 ASN A OD1 1 
ATOM   1242  N ND2 . ASN A 1 175 ? 146.185 103.514 114.723 1.00 33.65  ? 175 ASN A ND2 1 
ATOM   1243  N N   . PHE A 1 176 ? 145.309 108.080 112.795 1.00 30.60  ? 176 PHE A N   1 
ATOM   1244  C CA  . PHE A 1 176 ? 145.591 109.405 113.325 1.00 30.60  ? 176 PHE A CA  1 
ATOM   1245  C C   . PHE A 1 176 ? 145.353 110.440 112.236 1.00 30.60  ? 176 PHE A C   1 
ATOM   1246  O O   . PHE A 1 176 ? 145.335 110.126 111.044 1.00 30.60  ? 176 PHE A O   1 
ATOM   1247  C CB  . PHE A 1 176 ? 147.027 109.512 113.861 1.00 30.60  ? 176 PHE A CB  1 
ATOM   1248  C CG  . PHE A 1 176 ? 148.072 108.988 112.915 1.00 30.60  ? 176 PHE A CG  1 
ATOM   1249  C CD1 . PHE A 1 176 ? 148.577 109.789 111.904 1.00 30.60  ? 176 PHE A CD1 1 
ATOM   1250  C CD2 . PHE A 1 176 ? 148.554 107.697 113.040 1.00 30.60  ? 176 PHE A CD2 1 
ATOM   1251  C CE1 . PHE A 1 176 ? 149.536 109.311 111.036 1.00 30.60  ? 176 PHE A CE1 1 
ATOM   1252  C CE2 . PHE A 1 176 ? 149.514 107.215 112.175 1.00 30.60  ? 176 PHE A CE2 1 
ATOM   1253  C CZ  . PHE A 1 176 ? 150.005 108.022 111.172 1.00 30.60  ? 176 PHE A CZ  1 
ATOM   1254  N N   . ASP A 1 177 ? 145.166 111.686 112.665 1.00 29.43  ? 177 ASP A N   1 
ATOM   1255  C CA  . ASP A 1 177 ? 144.907 112.774 111.735 1.00 29.43  ? 177 ASP A CA  1 
ATOM   1256  C C   . ASP A 1 177 ? 146.163 113.140 110.952 1.00 29.43  ? 177 ASP A C   1 
ATOM   1257  O O   . ASP A 1 177 ? 147.289 113.024 111.443 1.00 29.43  ? 177 ASP A O   1 
ATOM   1258  C CB  . ASP A 1 177 ? 144.395 114.006 112.480 1.00 29.43  ? 177 ASP A CB  1 
ATOM   1259  C CG  . ASP A 1 177 ? 143.098 113.747 113.213 1.00 29.43  ? 177 ASP A CG  1 
ATOM   1260  O OD1 . ASP A 1 177 ? 142.477 112.694 112.971 1.00 29.43  ? 177 ASP A OD1 1 
ATOM   1261  O OD2 . ASP A 1 177 ? 142.699 114.600 114.031 1.00 29.43  ? 177 ASP A OD2 1 
ATOM   1262  N N   . LYS A 1 178 ? 145.955 113.596 109.721 1.00 22.37  ? 178 LYS A N   1 
ATOM   1263  C CA  . LYS A 1 178 ? 147.015 114.096 108.863 1.00 22.37  ? 178 LYS A CA  1 
ATOM   1264  C C   . LYS A 1 178 ? 146.854 115.598 108.669 1.00 22.37  ? 178 LYS A C   1 
ATOM   1265  O O   . LYS A 1 178 ? 145.737 116.118 108.636 1.00 22.37  ? 178 LYS A O   1 
ATOM   1266  C CB  . LYS A 1 178 ? 147.000 113.404 107.498 1.00 22.37  ? 178 LYS A CB  1 
ATOM   1267  C CG  . LYS A 1 178 ? 147.373 111.939 107.520 1.00 22.37  ? 178 LYS A CG  1 
ATOM   1268  C CD  . LYS A 1 178 ? 147.141 111.316 106.157 1.00 22.37  ? 178 LYS A CD  1 
ATOM   1269  C CE  . LYS A 1 178 ? 147.868 109.997 106.016 1.00 22.37  ? 178 LYS A CE  1 
ATOM   1270  N NZ  . LYS A 1 178 ? 147.859 109.510 104.612 1.00 22.37  ? 178 LYS A NZ  1 
ATOM   1271  N N   . LEU A 1 179 ? 147.981 116.292 108.546 1.00 19.65  ? 179 LEU A N   1 
ATOM   1272  C CA  . LEU A 1 179 ? 147.997 117.720 108.260 1.00 19.65  ? 179 LEU A CA  1 
ATOM   1273  C C   . LEU A 1 179 ? 148.764 117.956 106.968 1.00 19.65  ? 179 LEU A C   1 
ATOM   1274  O O   . LEU A 1 179 ? 149.910 117.517 106.835 1.00 19.65  ? 179 LEU A O   1 
ATOM   1275  C CB  . LEU A 1 179 ? 148.627 118.508 109.408 1.00 19.65  ? 179 LEU A CB  1 
ATOM   1276  C CG  . LEU A 1 179 ? 148.764 120.017 109.202 1.00 19.65  ? 179 LEU A CG  1 
ATOM   1277  C CD1 . LEU A 1 179 ? 147.411 120.700 109.264 1.00 19.65  ? 179 LEU A CD1 1 
ATOM   1278  C CD2 . LEU A 1 179 ? 149.703 120.600 110.234 1.00 19.65  ? 179 LEU A CD2 1 
ATOM   1279  N N   . TYR A 1 180 ? 148.134 118.650 106.025 1.00 19.02  ? 180 TYR A N   1 
ATOM   1280  C CA  . TYR A 1 180 ? 148.711 118.917 104.715 1.00 19.02  ? 180 TYR A CA  1 
ATOM   1281  C C   . TYR A 1 180 ? 148.908 120.415 104.549 1.00 19.02  ? 180 TYR A C   1 
ATOM   1282  O O   . TYR A 1 180 ? 148.004 121.198 104.851 1.00 19.02  ? 180 TYR A O   1 
ATOM   1283  C CB  . TYR A 1 180 ? 147.813 118.379 103.597 1.00 19.02  ? 180 TYR A CB  1 
ATOM   1284  C CG  . TYR A 1 180 ? 147.899 116.885 103.395 1.00 19.02  ? 180 TYR A CG  1 
ATOM   1285  C CD1 . TYR A 1 180 ? 148.882 116.331 102.589 1.00 19.02  ? 180 TYR A CD1 1 
ATOM   1286  C CD2 . TYR A 1 180 ? 146.993 116.029 104.004 1.00 19.02  ? 180 TYR A CD2 1 
ATOM   1287  C CE1 . TYR A 1 180 ? 148.962 114.969 102.398 1.00 19.02  ? 180 TYR A CE1 1 
ATOM   1288  C CE2 . TYR A 1 180 ? 147.067 114.665 103.819 1.00 19.02  ? 180 TYR A CE2 1 
ATOM   1289  C CZ  . TYR A 1 180 ? 148.053 114.141 103.015 1.00 19.02  ? 180 TYR A CZ  1 
ATOM   1290  O OH  . TYR A 1 180 ? 148.133 112.782 102.827 1.00 19.02  ? 180 TYR A OH  1 
ATOM   1291  N N   . ILE A 1 181 ? 150.085 120.807 104.071 1.00 18.05  ? 181 ILE A N   1 
ATOM   1292  C CA  . ILE A 1 181 ? 150.409 122.204 103.805 1.00 18.05  ? 181 ILE A CA  1 
ATOM   1293  C C   . ILE A 1 181 ? 150.629 122.353 102.306 1.00 18.05  ? 181 ILE A C   1 
ATOM   1294  O O   . ILE A 1 181 ? 151.480 121.668 101.726 1.00 18.05  ? 181 ILE A O   1 
ATOM   1295  C CB  . ILE A 1 181 ? 151.645 122.662 104.596 1.00 18.05  ? 181 ILE A CB  1 
ATOM   1296  C CG1 . ILE A 1 181 ? 151.509 122.289 106.075 1.00 18.05  ? 181 ILE A CG1 1 
ATOM   1297  C CG2 . ILE A 1 181 ? 151.860 124.158 104.434 1.00 18.05  ? 181 ILE A CG2 1 
ATOM   1298  C CD1 . ILE A 1 181 ? 150.576 123.182 106.855 1.00 18.05  ? 181 ILE A CD1 1 
ATOM   1299  N N   . TRP A 1 182 ? 149.864 123.245 101.681 1.00 17.26  ? 182 TRP A N   1 
ATOM   1300  C CA  . TRP A 1 182 ? 149.960 123.499 100.250 1.00 17.26  ? 182 TRP A CA  1 
ATOM   1301  C C   . TRP A 1 182 ? 149.918 125.004 100.023 1.00 17.26  ? 182 TRP A C   1 
ATOM   1302  O O   . TRP A 1 182 ? 149.739 125.788 100.960 1.00 17.26  ? 182 TRP A O   1 
ATOM   1303  C CB  . TRP A 1 182 ? 148.846 122.779 99.480  1.00 17.26  ? 182 TRP A CB  1 
ATOM   1304  C CG  . TRP A 1 182 ? 147.483 122.929 100.087 1.00 17.26  ? 182 TRP A CG  1 
ATOM   1305  C CD1 . TRP A 1 182 ? 146.986 122.251 101.160 1.00 17.26  ? 182 TRP A CD1 1 
ATOM   1306  C CD2 . TRP A 1 182 ? 146.439 123.805 99.648  1.00 17.26  ? 182 TRP A CD2 1 
ATOM   1307  N NE1 . TRP A 1 182 ? 145.701 122.655 101.422 1.00 17.26  ? 182 TRP A NE1 1 
ATOM   1308  C CE2 . TRP A 1 182 ? 145.341 123.608 100.507 1.00 17.26  ? 182 TRP A CE2 1 
ATOM   1309  C CE3 . TRP A 1 182 ? 146.326 124.739 98.614  1.00 17.26  ? 182 TRP A CE3 1 
ATOM   1310  C CZ2 . TRP A 1 182 ? 144.147 124.308 100.363 1.00 17.26  ? 182 TRP A CZ2 1 
ATOM   1311  C CZ3 . TRP A 1 182 ? 145.142 125.433 98.474  1.00 17.26  ? 182 TRP A CZ3 1 
ATOM   1312  C CH2 . TRP A 1 182 ? 144.067 125.214 99.343  1.00 17.26  ? 182 TRP A CH2 1 
ATOM   1313  N N   . GLY A 1 183 ? 150.081 125.416 98.766  1.00 18.96  ? 183 GLY A N   1 
ATOM   1314  C CA  . GLY A 1 183 ? 150.152 126.830 98.463  1.00 18.96  ? 183 GLY A CA  1 
ATOM   1315  C C   . GLY A 1 183 ? 149.655 127.171 97.075  1.00 18.96  ? 183 GLY A C   1 
ATOM   1316  O O   . GLY A 1 183 ? 149.386 126.299 96.247  1.00 18.96  ? 183 GLY A O   1 
ATOM   1317  N N   . VAL A 1 184 ? 149.535 128.477 96.838  1.00 20.51  ? 184 VAL A N   1 
ATOM   1318  C CA  . VAL A 1 184 ? 149.125 129.039 95.557  1.00 20.51  ? 184 VAL A CA  1 
ATOM   1319  C C   . VAL A 1 184 ? 150.093 130.156 95.198  1.00 20.51  ? 184 VAL A C   1 
ATOM   1320  O O   . VAL A 1 184 ? 150.451 130.974 96.053  1.00 20.51  ? 184 VAL A O   1 
ATOM   1321  C CB  . VAL A 1 184 ? 147.675 129.572 95.599  1.00 20.51  ? 184 VAL A CB  1 
ATOM   1322  C CG1 . VAL A 1 184 ? 147.258 130.103 94.236  1.00 20.51  ? 184 VAL A CG1 1 
ATOM   1323  C CG2 . VAL A 1 184 ? 146.714 128.491 96.063  1.00 20.51  ? 184 VAL A CG2 1 
ATOM   1324  N N   . HIS A 1 185 ? 150.513 130.196 93.937  1.00 21.14  ? 185 HIS A N   1 
ATOM   1325  C CA  . HIS A 1 185 ? 151.465 131.192 93.460  1.00 21.14  ? 185 HIS A CA  1 
ATOM   1326  C C   . HIS A 1 185 ? 150.728 132.338 92.779  1.00 21.14  ? 185 HIS A C   1 
ATOM   1327  O O   . HIS A 1 185 ? 149.903 132.111 91.889  1.00 21.14  ? 185 HIS A O   1 
ATOM   1328  C CB  . HIS A 1 185 ? 152.469 130.565 92.492  1.00 21.14  ? 185 HIS A CB  1 
ATOM   1329  C CG  . HIS A 1 185 ? 153.506 131.524 91.995  1.00 21.14  ? 185 HIS A CG  1 
ATOM   1330  N ND1 . HIS A 1 185 ? 153.735 131.743 90.654  1.00 21.14  ? 185 HIS A ND1 1 
ATOM   1331  C CD2 . HIS A 1 185 ? 154.375 132.322 92.659  1.00 21.14  ? 185 HIS A CD2 1 
ATOM   1332  C CE1 . HIS A 1 185 ? 154.700 132.634 90.514  1.00 21.14  ? 185 HIS A CE1 1 
ATOM   1333  N NE2 . HIS A 1 185 ? 155.105 133.001 91.715  1.00 21.14  ? 185 HIS A NE2 1 
ATOM   1334  N N   . HIS A 1 186 ? 151.034 133.567 93.198  1.00 22.46  ? 186 HIS A N   1 
ATOM   1335  C CA  . HIS A 1 186 ? 150.433 134.755 92.613  1.00 22.46  ? 186 HIS A CA  1 
ATOM   1336  C C   . HIS A 1 186 ? 151.443 135.430 91.699  1.00 22.46  ? 186 HIS A C   1 
ATOM   1337  O O   . HIS A 1 186 ? 152.402 136.036 92.198  1.00 22.46  ? 186 HIS A O   1 
ATOM   1338  C CB  . HIS A 1 186 ? 149.981 135.722 93.705  1.00 22.46  ? 186 HIS A CB  1 
ATOM   1339  C CG  . HIS A 1 186 ? 149.032 135.122 94.694  1.00 22.46  ? 186 HIS A CG  1 
ATOM   1340  N ND1 . HIS A 1 186 ? 147.715 134.853 94.393  1.00 22.46  ? 186 HIS A ND1 1 
ATOM   1341  C CD2 . HIS A 1 186 ? 149.207 134.747 95.983  1.00 22.46  ? 186 HIS A CD2 1 
ATOM   1342  C CE1 . HIS A 1 186 ? 147.120 134.332 95.451  1.00 22.46  ? 186 HIS A CE1 1 
ATOM   1343  N NE2 . HIS A 1 186 ? 148.004 134.258 96.430  1.00 22.46  ? 186 HIS A NE2 1 
ATOM   1344  N N   . PRO A 1 187 ? 151.280 135.367 90.381  1.00 24.07  ? 187 PRO A N   1 
ATOM   1345  C CA  . PRO A 1 187 ? 152.227 136.038 89.483  1.00 24.07  ? 187 PRO A CA  1 
ATOM   1346  C C   . PRO A 1 187 ? 152.043 137.548 89.513  1.00 24.07  ? 187 PRO A C   1 
ATOM   1347  O O   . PRO A 1 187 ? 151.078 138.082 90.062  1.00 24.07  ? 187 PRO A O   1 
ATOM   1348  C CB  . PRO A 1 187 ? 151.893 135.459 88.104  1.00 24.07  ? 187 PRO A CB  1 
ATOM   1349  C CG  . PRO A 1 187 ? 151.019 134.269 88.370  1.00 24.07  ? 187 PRO A CG  1 
ATOM   1350  C CD  . PRO A 1 187 ? 150.293 134.573 89.636  1.00 24.07  ? 187 PRO A CD  1 
ATOM   1351  N N   . SER A 1 188 ? 153.005 138.245 88.907  1.00 27.60  ? 188 SER A N   1 
ATOM   1352  C CA  . SER A 1 188 ? 152.994 139.701 88.885  1.00 27.60  ? 188 SER A CA  1 
ATOM   1353  C C   . SER A 1 188 ? 152.495 140.289 87.571  1.00 27.60  ? 188 SER A C   1 
ATOM   1354  O O   . SER A 1 188 ? 152.044 141.439 87.562  1.00 27.60  ? 188 SER A O   1 
ATOM   1355  C CB  . SER A 1 188 ? 154.396 140.247 89.179  1.00 27.60  ? 188 SER A CB  1 
ATOM   1356  O OG  . SER A 1 188 ? 155.371 139.617 88.370  1.00 27.60  ? 188 SER A OG  1 
ATOM   1357  N N   . THR A 1 189 ? 152.561 139.542 86.471  1.00 29.70  ? 189 THR A N   1 
ATOM   1358  C CA  . THR A 1 189 ? 152.076 140.013 85.181  1.00 29.70  ? 189 THR A CA  1 
ATOM   1359  C C   . THR A 1 189 ? 151.327 138.885 84.485  1.00 29.70  ? 189 THR A C   1 
ATOM   1360  O O   . THR A 1 189 ? 151.442 137.713 84.850  1.00 29.70  ? 189 THR A O   1 
ATOM   1361  C CB  . THR A 1 189 ? 153.217 140.518 84.284  1.00 29.70  ? 189 THR A CB  1 
ATOM   1362  O OG1 . THR A 1 189 ? 154.232 139.513 84.179  1.00 29.70  ? 189 THR A OG1 1 
ATOM   1363  C CG2 . THR A 1 189 ? 153.826 141.795 84.842  1.00 29.70  ? 189 THR A CG2 1 
ATOM   1364  N N   . ASN A 1 190 ? 150.541 139.257 83.473  1.00 31.21  ? 190 ASN A N   1 
ATOM   1365  C CA  . ASN A 1 190 ? 149.857 138.256 82.660  1.00 31.21  ? 190 ASN A CA  1 
ATOM   1366  C C   . ASN A 1 190 ? 150.846 137.471 81.808  1.00 31.21  ? 190 ASN A C   1 
ATOM   1367  O O   . ASN A 1 190 ? 150.666 136.267 81.587  1.00 31.21  ? 190 ASN A O   1 
ATOM   1368  C CB  . ASN A 1 190 ? 148.804 138.925 81.777  1.00 31.21  ? 190 ASN A CB  1 
ATOM   1369  C CG  . ASN A 1 190 ? 147.575 139.351 82.554  1.00 31.21  ? 190 ASN A CG  1 
ATOM   1370  O OD1 . ASN A 1 190 ? 146.918 138.533 83.196  1.00 31.21  ? 190 ASN A OD1 1 
ATOM   1371  N ND2 . ASN A 1 190 ? 147.257 140.637 82.495  1.00 31.21  ? 190 ASN A ND2 1 
ATOM   1372  N N   . GLN A 1 191 ? 151.890 138.140 81.314  1.00 33.27  ? 191 GLN A N   1 
ATOM   1373  C CA  . GLN A 1 191 ? 152.898 137.458 80.510  1.00 33.27  ? 191 GLN A CA  1 
ATOM   1374  C C   . GLN A 1 191 ? 153.618 136.391 81.325  1.00 33.27  ? 191 GLN A C   1 
ATOM   1375  O O   . GLN A 1 191 ? 153.842 135.277 80.840  1.00 33.27  ? 191 GLN A O   1 
ATOM   1376  C CB  . GLN A 1 191 ? 153.887 138.479 79.942  1.00 33.27  ? 191 GLN A CB  1 
ATOM   1377  C CG  . GLN A 1 191 ? 154.880 137.925 78.926  1.00 33.27  ? 191 GLN A CG  1 
ATOM   1378  C CD  . GLN A 1 191 ? 156.117 137.327 79.568  1.00 33.27  ? 191 GLN A CD  1 
ATOM   1379  O OE1 . GLN A 1 191 ? 156.536 137.748 80.646  1.00 33.27  ? 191 GLN A OE1 1 
ATOM   1380  N NE2 . GLN A 1 191 ? 156.710 136.341 78.905  1.00 33.27  ? 191 GLN A NE2 1 
ATOM   1381  N N   . GLU A 1 192 ? 153.975 136.708 82.571  1.00 31.78  ? 192 GLU A N   1 
ATOM   1382  C CA  . GLU A 1 192 ? 154.594 135.713 83.442  1.00 31.78  ? 192 GLU A CA  1 
ATOM   1383  C C   . GLU A 1 192 ? 153.634 134.570 83.745  1.00 31.78  ? 192 GLU A C   1 
ATOM   1384  O O   . GLU A 1 192 ? 154.042 133.402 83.787  1.00 31.78  ? 192 GLU A O   1 
ATOM   1385  C CB  . GLU A 1 192 ? 155.065 136.371 84.737  1.00 31.78  ? 192 GLU A CB  1 
ATOM   1386  C CG  . GLU A 1 192 ? 155.743 135.418 85.703  1.00 31.78  ? 192 GLU A CG  1 
ATOM   1387  C CD  . GLU A 1 192 ? 155.903 136.011 87.086  1.00 31.78  ? 192 GLU A CD  1 
ATOM   1388  O OE1 . GLU A 1 192 ? 154.922 136.582 87.605  1.00 31.78  ? 192 GLU A OE1 1 
ATOM   1389  O OE2 . GLU A 1 192 ? 157.009 135.908 87.654  1.00 31.78  ? 192 GLU A OE2 1 
ATOM   1390  N N   . GLN A 1 193 ? 152.356 134.890 83.964  1.00 28.45  ? 193 GLN A N   1 
ATOM   1391  C CA  . GLN A 1 193 ? 151.365 133.856 84.237  1.00 28.45  ? 193 GLN A CA  1 
ATOM   1392  C C   . GLN A 1 193 ? 151.257 132.883 83.072  1.00 28.45  ? 193 GLN A C   1 
ATOM   1393  O O   . GLN A 1 193 ? 151.229 131.664 83.270  1.00 28.45  ? 193 GLN A O   1 
ATOM   1394  C CB  . GLN A 1 193 ? 150.008 134.496 84.533  1.00 28.45  ? 193 GLN A CB  1 
ATOM   1395  C CG  . GLN A 1 193 ? 148.814 133.604 84.230  1.00 28.45  ? 193 GLN A CG  1 
ATOM   1396  C CD  . GLN A 1 193 ? 148.502 132.634 85.351  1.00 28.45  ? 193 GLN A CD  1 
ATOM   1397  O OE1 . GLN A 1 193 ? 148.646 132.961 86.527  1.00 28.45  ? 193 GLN A OE1 1 
ATOM   1398  N NE2 . GLN A 1 193 ? 148.069 131.433 84.991  1.00 28.45  ? 193 GLN A NE2 1 
ATOM   1399  N N   . THR A 1 194 ? 151.212 133.404 81.844  1.00 30.05  ? 194 THR A N   1 
ATOM   1400  C CA  . THR A 1 194 ? 151.107 132.526 80.683  1.00 30.05  ? 194 THR A CA  1 
ATOM   1401  C C   . THR A 1 194 ? 152.418 131.805 80.398  1.00 30.05  ? 194 THR A C   1 
ATOM   1402  O O   . THR A 1 194 ? 152.406 130.701 79.842  1.00 30.05  ? 194 THR A O   1 
ATOM   1403  C CB  . THR A 1 194 ? 150.661 133.317 79.454  1.00 30.05  ? 194 THR A CB  1 
ATOM   1404  O OG1 . THR A 1 194 ? 151.446 134.509 79.338  1.00 30.05  ? 194 THR A OG1 1 
ATOM   1405  C CG2 . THR A 1 194 ? 149.191 133.688 79.566  1.00 30.05  ? 194 THR A CG2 1 
ATOM   1406  N N   . ASN A 1 195 ? 153.553 132.405 80.762  1.00 33.21  ? 195 ASN A N   1 
ATOM   1407  C CA  . ASN A 1 195 ? 154.838 131.752 80.544  1.00 33.21  ? 195 ASN A CA  1 
ATOM   1408  C C   . ASN A 1 195 ? 155.009 130.558 81.475  1.00 33.21  ? 195 ASN A C   1 
ATOM   1409  O O   . ASN A 1 195 ? 155.418 129.474 81.042  1.00 33.21  ? 195 ASN A O   1 
ATOM   1410  C CB  . ASN A 1 195 ? 155.971 132.762 80.740  1.00 33.21  ? 195 ASN A CB  1 
ATOM   1411  C CG  . ASN A 1 195 ? 157.325 132.216 80.329  1.00 33.21  ? 195 ASN A CG  1 
ATOM   1412  O OD1 . ASN A 1 195 ? 157.450 131.065 79.913  1.00 33.21  ? 195 ASN A OD1 1 
ATOM   1413  N ND2 . ASN A 1 195 ? 158.353 133.048 80.445  1.00 33.21  ? 195 ASN A ND2 1 
ATOM   1414  N N   . LEU A 1 196 ? 154.703 130.737 82.762  1.00 29.64  ? 196 LEU A N   1 
ATOM   1415  C CA  . LEU A 1 196 ? 154.846 129.631 83.704  1.00 29.64  ? 196 LEU A CA  1 
ATOM   1416  C C   . LEU A 1 196 ? 153.740 128.599 83.522  1.00 29.64  ? 196 LEU A C   1 
ATOM   1417  O O   . LEU A 1 196 ? 154.005 127.392 83.513  1.00 29.64  ? 196 LEU A O   1 
ATOM   1418  C CB  . LEU A 1 196 ? 154.858 130.158 85.138  1.00 29.64  ? 196 LEU A CB  1 
ATOM   1419  C CG  . LEU A 1 196 ? 156.069 130.993 85.556  1.00 29.64  ? 196 LEU A CG  1 
ATOM   1420  C CD1 . LEU A 1 196 ? 156.124 131.128 87.066  1.00 29.64  ? 196 LEU A CD1 1 
ATOM   1421  C CD2 . LEU A 1 196 ? 157.355 130.385 85.024  1.00 29.64  ? 196 LEU A CD2 1 
ATOM   1422  N N   . TYR A 1 197 ? 152.498 129.052 83.375  1.00 28.38  ? 197 TYR A N   1 
ATOM   1423  C CA  . TYR A 1 197 ? 151.341 128.174 83.271  1.00 28.38  ? 197 TYR A CA  1 
ATOM   1424  C C   . TYR A 1 197 ? 150.583 128.537 82.004  1.00 28.38  ? 197 TYR A C   1 
ATOM   1425  O O   . TYR A 1 197 ? 150.232 129.702 81.806  1.00 28.38  ? 197 TYR A O   1 
ATOM   1426  C CB  . TYR A 1 197 ? 150.441 128.317 84.501  1.00 28.38  ? 197 TYR A CB  1 
ATOM   1427  C CG  . TYR A 1 197 ? 151.220 128.411 85.793  1.00 28.38  ? 197 TYR A CG  1 
ATOM   1428  C CD1 . TYR A 1 197 ? 151.832 127.295 86.344  1.00 28.38  ? 197 TYR A CD1 1 
ATOM   1429  C CD2 . TYR A 1 197 ? 151.358 129.625 86.452  1.00 28.38  ? 197 TYR A CD2 1 
ATOM   1430  C CE1 . TYR A 1 197 ? 152.553 127.386 87.520  1.00 28.38  ? 197 TYR A CE1 1 
ATOM   1431  C CE2 . TYR A 1 197 ? 152.074 129.724 87.625  1.00 28.38  ? 197 TYR A CE2 1 
ATOM   1432  C CZ  . TYR A 1 197 ? 152.669 128.603 88.156  1.00 28.38  ? 197 TYR A CZ  1 
ATOM   1433  O OH  . TYR A 1 197 ? 153.382 128.703 89.326  1.00 28.38  ? 197 TYR A OH  1 
ATOM   1434  N N   . VAL A 1 198 ? 150.328 127.543 81.153  1.00 30.02  ? 198 VAL A N   1 
ATOM   1435  C CA  . VAL A 1 198 ? 149.775 127.828 79.830  1.00 30.02  ? 198 VAL A CA  1 
ATOM   1436  C C   . VAL A 1 198 ? 148.421 128.520 79.941  1.00 30.02  ? 198 VAL A C   1 
ATOM   1437  O O   . VAL A 1 198 ? 148.098 129.412 79.147  1.00 30.02  ? 198 VAL A O   1 
ATOM   1438  C CB  . VAL A 1 198 ? 149.689 126.534 79.002  1.00 30.02  ? 198 VAL A CB  1 
ATOM   1439  C CG1 . VAL A 1 198 ? 149.325 126.848 77.564  1.00 30.02  ? 198 VAL A CG1 1 
ATOM   1440  C CG2 . VAL A 1 198 ? 151.010 125.794 79.064  1.00 30.02  ? 198 VAL A CG2 1 
ATOM   1441  N N   . GLN A 1 199 ? 147.614 128.130 80.922  1.00 30.98  ? 199 GLN A N   1 
ATOM   1442  C CA  . GLN A 1 199 ? 146.302 128.739 81.095  1.00 30.98  ? 199 GLN A CA  1 
ATOM   1443  C C   . GLN A 1 199 ? 146.436 130.176 81.585  1.00 30.98  ? 199 GLN A C   1 
ATOM   1444  O O   . GLN A 1 199 ? 147.331 130.503 82.368  1.00 30.98  ? 199 GLN A O   1 
ATOM   1445  C CB  . GLN A 1 199 ? 145.461 127.924 82.076  1.00 30.98  ? 199 GLN A CB  1 
ATOM   1446  C CG  . GLN A 1 199 ? 144.839 126.677 81.472  1.00 30.98  ? 199 GLN A CG  1 
ATOM   1447  C CD  . GLN A 1 199 ? 145.857 125.590 81.199  1.00 30.98  ? 199 GLN A CD  1 
ATOM   1448  O OE1 . GLN A 1 199 ? 146.412 124.998 82.123  1.00 30.98  ? 199 GLN A OE1 1 
ATOM   1449  N NE2 . GLN A 1 199 ? 146.114 125.327 79.924  1.00 30.98  ? 199 GLN A NE2 1 
ATOM   1450  N N   . ALA A 1 200 ? 145.531 131.037 81.119  1.00 31.57  ? 200 ALA A N   1 
ATOM   1451  C CA  . ALA A 1 200 ? 145.548 132.445 81.492  1.00 31.57  ? 200 ALA A CA  1 
ATOM   1452  C C   . ALA A 1 200 ? 144.912 132.710 82.849  1.00 31.57  ? 200 ALA A C   1 
ATOM   1453  O O   . ALA A 1 200 ? 144.993 133.840 83.341  1.00 31.57  ? 200 ALA A O   1 
ATOM   1454  C CB  . ALA A 1 200 ? 144.839 133.281 80.425  1.00 31.57  ? 200 ALA A CB  1 
ATOM   1455  N N   . SER A 1 201 ? 144.287 131.707 83.461  1.00 29.73  ? 201 SER A N   1 
ATOM   1456  C CA  . SER A 1 201 ? 143.667 131.871 84.773  1.00 29.73  ? 201 SER A CA  1 
ATOM   1457  C C   . SER A 1 201 ? 143.712 130.525 85.479  1.00 29.73  ? 201 SER A C   1 
ATOM   1458  O O   . SER A 1 201 ? 142.993 129.599 85.093  1.00 29.73  ? 201 SER A O   1 
ATOM   1459  C CB  . SER A 1 201 ? 142.233 132.379 84.644  1.00 29.73  ? 201 SER A CB  1 
ATOM   1460  O OG  . SER A 1 201 ? 141.622 132.514 85.915  1.00 29.73  ? 201 SER A OG  1 
ATOM   1461  N N   . GLY A 1 202 ? 144.557 130.415 86.502  1.00 25.73  ? 202 GLY A N   1 
ATOM   1462  C CA  . GLY A 1 202 ? 144.696 129.181 87.241  1.00 25.73  ? 202 GLY A CA  1 
ATOM   1463  C C   . GLY A 1 202 ? 143.617 129.007 88.290  1.00 25.73  ? 202 GLY A C   1 
ATOM   1464  O O   . GLY A 1 202 ? 142.789 129.883 88.536  1.00 25.73  ? 202 GLY A O   1 
ATOM   1465  N N   . ARG A 1 203 ? 143.640 127.838 88.926  1.00 25.01  ? 203 ARG A N   1 
ATOM   1466  C CA  . ARG A 1 203 ? 142.639 127.480 89.920  1.00 25.01  ? 203 ARG A CA  1 
ATOM   1467  C C   . ARG A 1 203 ? 143.119 126.254 90.681  1.00 25.01  ? 203 ARG A C   1 
ATOM   1468  O O   . ARG A 1 203 ? 143.612 125.301 90.074  1.00 25.01  ? 203 ARG A O   1 
ATOM   1469  C CB  . ARG A 1 203 ? 141.283 127.203 89.258  1.00 25.01  ? 203 ARG A CB  1 
ATOM   1470  C CG  . ARG A 1 203 ? 140.218 126.686 90.198  1.00 25.01  ? 203 ARG A CG  1 
ATOM   1471  C CD  . ARG A 1 203 ? 139.063 126.072 89.427  1.00 25.01  ? 203 ARG A CD  1 
ATOM   1472  N NE  . ARG A 1 203 ? 139.503 125.054 88.479  1.00 25.01  ? 203 ARG A NE  1 
ATOM   1473  C CZ  . ARG A 1 203 ? 139.882 123.828 88.814  1.00 25.01  ? 203 ARG A CZ  1 
ATOM   1474  N NH1 . ARG A 1 203 ? 139.899 123.429 90.075  1.00 25.01  ? 203 ARG A NH1 1 
ATOM   1475  N NH2 . ARG A 1 203 ? 140.250 122.979 87.859  1.00 25.01  ? 203 ARG A NH2 1 
ATOM   1476  N N   . VAL A 1 204 ? 142.978 126.287 92.005  1.00 23.19  ? 204 VAL A N   1 
ATOM   1477  C CA  . VAL A 1 204 ? 143.392 125.192 92.874  1.00 23.19  ? 204 VAL A CA  1 
ATOM   1478  C C   . VAL A 1 204 ? 142.225 124.821 93.776  1.00 23.19  ? 204 VAL A C   1 
ATOM   1479  O O   . VAL A 1 204 ? 141.666 125.685 94.460  1.00 23.19  ? 204 VAL A O   1 
ATOM   1480  C CB  . VAL A 1 204 ? 144.626 125.562 93.721  1.00 23.19  ? 204 VAL A CB  1 
ATOM   1481  C CG1 . VAL A 1 204 ? 145.048 124.383 94.579  1.00 23.19  ? 204 VAL A CG1 1 
ATOM   1482  C CG2 . VAL A 1 204 ? 145.773 126.013 92.831  1.00 23.19  ? 204 VAL A CG2 1 
ATOM   1483  N N   . THR A 1 205 ? 141.863 123.539 93.783  1.00 23.90  ? 205 THR A N   1 
ATOM   1484  C CA  . THR A 1 205 ? 140.806 123.021 94.645  1.00 23.90  ? 205 THR A CA  1 
ATOM   1485  C C   . THR A 1 205 ? 141.361 121.860 95.455  1.00 23.90  ? 205 THR A C   1 
ATOM   1486  O O   . THR A 1 205 ? 141.877 120.894 94.885  1.00 23.90  ? 205 THR A O   1 
ATOM   1487  C CB  . THR A 1 205 ? 139.592 122.568 93.828  1.00 23.90  ? 205 THR A CB  1 
ATOM   1488  O OG1 . THR A 1 205 ? 139.265 123.567 92.855  1.00 23.90  ? 205 THR A OG1 1 
ATOM   1489  C CG2 . THR A 1 205 ? 138.391 122.343 94.736  1.00 23.90  ? 205 THR A CG2 1 
ATOM   1490  N N   . VAL A 1 206 ? 141.257 121.955 96.779  1.00 21.86  ? 206 VAL A N   1 
ATOM   1491  C CA  . VAL A 1 206 ? 141.664 120.890 97.690  1.00 21.86  ? 206 VAL A CA  1 
ATOM   1492  C C   . VAL A 1 206 ? 140.492 120.610 98.618  1.00 21.86  ? 206 VAL A C   1 
ATOM   1493  O O   . VAL A 1 206 ? 140.020 121.516 99.315  1.00 21.86  ? 206 VAL A O   1 
ATOM   1494  C CB  . VAL A 1 206 ? 142.920 121.261 98.496  1.00 21.86  ? 206 VAL A CB  1 
ATOM   1495  C CG1 . VAL A 1 206 ? 143.285 120.142 99.452  1.00 21.86  ? 206 VAL A CG1 1 
ATOM   1496  C CG2 . VAL A 1 206 ? 144.081 121.560 97.565  1.00 21.86  ? 206 VAL A CG2 1 
ATOM   1497  N N   . SER A 1 207 ? 140.027 119.363 98.635  1.00 25.18  ? 207 SER A N   1 
ATOM   1498  C CA  . SER A 1 207 ? 138.802 119.034 99.348  1.00 25.18  ? 207 SER A CA  1 
ATOM   1499  C C   . SER A 1 207 ? 138.888 117.631 99.929  1.00 25.18  ? 207 SER A C   1 
ATOM   1500  O O   . SER A 1 207 ? 139.682 116.797 99.488  1.00 25.18  ? 207 SER A O   1 
ATOM   1501  C CB  . SER A 1 207 ? 137.581 119.143 98.429  1.00 25.18  ? 207 SER A CB  1 
ATOM   1502  O OG  . SER A 1 207 ? 137.780 118.403 97.239  1.00 25.18  ? 207 SER A OG  1 
ATOM   1503  N N   . THR A 1 208 ? 138.053 117.389 100.932 1.00 28.18  ? 208 THR A N   1 
ATOM   1504  C CA  . THR A 1 208 ? 137.825 116.076 101.518 1.00 28.18  ? 208 THR A CA  1 
ATOM   1505  C C   . THR A 1 208 ? 136.334 115.753 101.413 1.00 28.18  ? 208 THR A C   1 
ATOM   1506  O O   . THR A 1 208 ? 135.568 116.465 100.759 1.00 28.18  ? 208 THR A O   1 
ATOM   1507  C CB  . THR A 1 208 ? 138.315 116.027 102.968 1.00 28.18  ? 208 THR A CB  1 
ATOM   1508  O OG1 . THR A 1 208 ? 137.589 116.978 103.754 1.00 28.18  ? 208 THR A OG1 1 
ATOM   1509  C CG2 . THR A 1 208 ? 139.797 116.345 103.045 1.00 28.18  ? 208 THR A CG2 1 
ATOM   1510  N N   . ARG A 1 209 ? 135.922 114.663 102.061 1.00 29.53  ? 209 ARG A N   1 
ATOM   1511  C CA  . ARG A 1 209 ? 134.513 114.290 102.057 1.00 29.53  ? 209 ARG A CA  1 
ATOM   1512  C C   . ARG A 1 209 ? 133.641 115.247 102.859 1.00 29.53  ? 209 ARG A C   1 
ATOM   1513  O O   . ARG A 1 209 ? 132.413 115.164 102.759 1.00 29.53  ? 209 ARG A O   1 
ATOM   1514  C CB  . ARG A 1 209 ? 134.337 112.873 102.601 1.00 29.53  ? 209 ARG A CB  1 
ATOM   1515  C CG  . ARG A 1 209 ? 134.861 111.784 101.687 1.00 29.53  ? 209 ARG A CG  1 
ATOM   1516  C CD  . ARG A 1 209 ? 133.988 110.545 101.764 1.00 29.53  ? 209 ARG A CD  1 
ATOM   1517  N NE  . ARG A 1 209 ? 134.671 109.361 101.259 1.00 29.53  ? 209 ARG A NE  1 
ATOM   1518  C CZ  . ARG A 1 209 ? 135.424 108.560 102.000 1.00 29.53  ? 209 ARG A CZ  1 
ATOM   1519  N NH1 . ARG A 1 209 ? 135.610 108.784 103.290 1.00 29.53  ? 209 ARG A NH1 1 
ATOM   1520  N NH2 . ARG A 1 209 ? 136.003 107.506 101.432 1.00 29.53  ? 209 ARG A NH2 1 
ATOM   1521  N N   . ARG A 1 210 ? 134.235 116.146 103.646 1.00 30.65  ? 210 ARG A N   1 
ATOM   1522  C CA  . ARG A 1 210 ? 133.469 117.031 104.509 1.00 30.65  ? 210 ARG A CA  1 
ATOM   1523  C C   . ARG A 1 210 ? 133.870 118.497 104.415 1.00 30.65  ? 210 ARG A C   1 
ATOM   1524  O O   . ARG A 1 210 ? 133.238 119.332 105.070 1.00 30.65  ? 210 ARG A O   1 
ATOM   1525  C CB  . ARG A 1 210 ? 133.585 116.574 105.971 1.00 30.65  ? 210 ARG A CB  1 
ATOM   1526  C CG  . ARG A 1 210 ? 135.015 116.467 106.471 1.00 30.65  ? 210 ARG A CG  1 
ATOM   1527  C CD  . ARG A 1 210 ? 135.063 116.322 107.982 1.00 30.65  ? 210 ARG A CD  1 
ATOM   1528  N NE  . ARG A 1 210 ? 135.061 117.612 108.661 1.00 30.65  ? 210 ARG A NE  1 
ATOM   1529  C CZ  . ARG A 1 210 ? 136.095 118.442 108.705 1.00 30.65  ? 210 ARG A CZ  1 
ATOM   1530  N NH1 . ARG A 1 210 ? 137.248 118.143 108.129 1.00 30.65  ? 210 ARG A NH1 1 
ATOM   1531  N NH2 . ARG A 1 210 ? 135.970 119.600 109.347 1.00 30.65  ? 210 ARG A NH2 1 
ATOM   1532  N N   . SER A 1 211 ? 134.888 118.839 103.628 1.00 28.90  ? 211 SER A N   1 
ATOM   1533  C CA  . SER A 1 211 ? 135.338 120.220 103.528 1.00 28.90  ? 211 SER A CA  1 
ATOM   1534  C C   . SER A 1 211 ? 135.929 120.459 102.147 1.00 28.90  ? 211 SER A C   1 
ATOM   1535  O O   . SER A 1 211 ? 136.282 119.520 101.430 1.00 28.90  ? 211 SER A O   1 
ATOM   1536  C CB  . SER A 1 211 ? 136.364 120.557 104.616 1.00 28.90  ? 211 SER A CB  1 
ATOM   1537  O OG  . SER A 1 211 ? 137.677 120.221 104.201 1.00 28.90  ? 211 SER A OG  1 
ATOM   1538  N N   . GLN A 1 212 ? 136.032 121.736 101.780 1.00 25.63  ? 212 GLN A N   1 
ATOM   1539  C CA  . GLN A 1 212 ? 136.573 122.120 100.485 1.00 25.63  ? 212 GLN A CA  1 
ATOM   1540  C C   . GLN A 1 212 ? 137.184 123.511 100.578 1.00 25.63  ? 212 GLN A C   1 
ATOM   1541  O O   . GLN A 1 212 ? 136.772 124.332 101.401 1.00 25.63  ? 212 GLN A O   1 
ATOM   1542  C CB  . GLN A 1 212 ? 135.495 122.098 99.396  1.00 25.63  ? 212 GLN A CB  1 
ATOM   1543  C CG  . GLN A 1 212 ? 134.425 123.163 99.576  1.00 25.63  ? 212 GLN A CG  1 
ATOM   1544  C CD  . GLN A 1 212 ? 133.394 123.149 98.470  1.00 25.63  ? 212 GLN A CD  1 
ATOM   1545  O OE1 . GLN A 1 212 ? 133.469 122.342 97.547  1.00 25.63  ? 212 GLN A OE1 1 
ATOM   1546  N NE2 . GLN A 1 212 ? 132.423 124.047 98.557  1.00 25.63  ? 212 GLN A NE2 1 
ATOM   1547  N N   . GLN A 1 213 ? 138.176 123.761 99.724  1.00 22.91  ? 213 GLN A N   1 
ATOM   1548  C CA  . GLN A 1 213 ? 138.788 125.077 99.588  1.00 22.91  ? 213 GLN A CA  1 
ATOM   1549  C C   . GLN A 1 213 ? 139.163 125.287 98.130  1.00 22.91  ? 213 GLN A C   1 
ATOM   1550  O O   . GLN A 1 213 ? 139.791 124.416 97.523  1.00 22.91  ? 213 GLN A O   1 
ATOM   1551  C CB  . GLN A 1 213 ? 140.035 125.220 100.470 1.00 22.91  ? 213 GLN A CB  1 
ATOM   1552  C CG  . GLN A 1 213 ? 139.772 125.243 101.964 1.00 22.91  ? 213 GLN A CG  1 
ATOM   1553  C CD  . GLN A 1 213 ? 141.011 124.924 102.775 1.00 22.91  ? 213 GLN A CD  1 
ATOM   1554  O OE1 . GLN A 1 213 ? 141.282 123.765 103.086 1.00 22.91  ? 213 GLN A OE1 1 
ATOM   1555  N NE2 . GLN A 1 213 ? 141.771 125.954 103.124 1.00 22.91  ? 213 GLN A NE2 1 
ATOM   1556  N N   . THR A 1 214 ? 138.780 126.434 97.574  1.00 24.40  ? 214 THR A N   1 
ATOM   1557  C CA  . THR A 1 214 ? 139.155 126.805 96.215  1.00 24.40  ? 214 THR A CA  1 
ATOM   1558  C C   . THR A 1 214 ? 139.746 128.205 96.226  1.00 24.40  ? 214 THR A C   1 
ATOM   1559  O O   . THR A 1 214 ? 139.156 129.127 96.798  1.00 24.40  ? 214 THR A O   1 
ATOM   1560  C CB  . THR A 1 214 ? 137.961 126.746 95.259  1.00 24.40  ? 214 THR A CB  1 
ATOM   1561  O OG1 . THR A 1 214 ? 137.180 125.577 95.537  1.00 24.40  ? 214 THR A OG1 1 
ATOM   1562  C CG2 . THR A 1 214 ? 138.442 126.697 93.814  1.00 24.40  ? 214 THR A CG2 1 
ATOM   1563  N N   . ILE A 1 215 ? 140.906 128.360 95.592  1.00 22.56  ? 215 ILE A N   1 
ATOM   1564  C CA  . ILE A 1 215 ? 141.643 129.617 95.575  1.00 22.56  ? 215 ILE A CA  1 
ATOM   1565  C C   . ILE A 1 215 ? 141.900 130.011 94.129  1.00 22.56  ? 215 ILE A C   1 
ATOM   1566  O O   . ILE A 1 215 ? 142.302 129.173 93.315  1.00 22.56  ? 215 ILE A O   1 
ATOM   1567  C CB  . ILE A 1 215 ? 142.973 129.512 96.347  1.00 22.56  ? 215 ILE A CB  1 
ATOM   1568  C CG1 . ILE A 1 215 ? 142.774 128.766 97.667  1.00 22.56  ? 215 ILE A CG1 1 
ATOM   1569  C CG2 . ILE A 1 215 ? 143.557 130.891 96.595  1.00 22.56  ? 215 ILE A CG2 1 
ATOM   1570  C CD1 . ILE A 1 215 ? 141.950 129.525 98.679  1.00 22.56  ? 215 ILE A CD1 1 
ATOM   1571  N N   . VAL A 1 216 ? 141.667 131.275 93.812  1.00 24.20  ? 216 VAL A N   1 
ATOM   1572  C CA  . VAL A 1 216 ? 141.960 131.843 92.498  1.00 24.20  ? 216 VAL A CA  1 
ATOM   1573  C C   . VAL A 1 216 ? 143.156 132.774 92.646  1.00 24.20  ? 216 VAL A C   1 
ATOM   1574  O O   . VAL A 1 216 ? 143.127 133.668 93.499  1.00 24.20  ? 216 VAL A O   1 
ATOM   1575  C CB  . VAL A 1 216 ? 140.751 132.601 91.915  1.00 24.20  ? 216 VAL A CB  1 
ATOM   1576  C CG1 . VAL A 1 216 ? 141.047 133.055 90.496  1.00 24.20  ? 216 VAL A CG1 1 
ATOM   1577  C CG2 . VAL A 1 216 ? 139.512 131.726 91.948  1.00 24.20  ? 216 VAL A CG2 1 
ATOM   1578  N N   . PRO A 1 217 ? 144.217 132.596 91.862  1.00 24.36  ? 217 PRO A N   1 
ATOM   1579  C CA  . PRO A 1 217 ? 145.391 133.464 92.002  1.00 24.36  ? 217 PRO A CA  1 
ATOM   1580  C C   . PRO A 1 217 ? 145.095 134.901 91.599  1.00 24.36  ? 217 PRO A C   1 
ATOM   1581  O O   . PRO A 1 217 ? 144.222 135.177 90.774  1.00 24.36  ? 217 PRO A O   1 
ATOM   1582  C CB  . PRO A 1 217 ? 146.419 132.827 91.059  1.00 24.36  ? 217 PRO A CB  1 
ATOM   1583  C CG  . PRO A 1 217 ? 145.614 132.011 90.107  1.00 24.36  ? 217 PRO A CG  1 
ATOM   1584  C CD  . PRO A 1 217 ? 144.431 131.525 90.878  1.00 24.36  ? 217 PRO A CD  1 
ATOM   1585  N N   . ASN A 1 218 ? 145.846 135.820 92.199  1.00 27.52  ? 218 ASN A N   1 
ATOM   1586  C CA  . ASN A 1 218 ? 145.734 137.245 91.925  1.00 27.52  ? 218 ASN A CA  1 
ATOM   1587  C C   . ASN A 1 218 ? 147.002 137.736 91.239  1.00 27.52  ? 218 ASN A C   1 
ATOM   1588  O O   . ASN A 1 218 ? 148.114 137.429 91.678  1.00 27.52  ? 218 ASN A O   1 
ATOM   1589  C CB  . ASN A 1 218 ? 145.502 138.035 93.215  1.00 27.52  ? 218 ASN A CB  1 
ATOM   1590  C CG  . ASN A 1 218 ? 144.374 137.468 94.053  1.00 27.52  ? 218 ASN A CG  1 
ATOM   1591  O OD1 . ASN A 1 218 ? 144.606 136.885 95.112  1.00 27.52  ? 218 ASN A OD1 1 
ATOM   1592  N ND2 . ASN A 1 218 ? 143.144 137.636 93.584  1.00 27.52  ? 218 ASN A ND2 1 
ATOM   1593  N N   . ILE A 1 219 ? 146.832 138.504 90.167  1.00 26.80  ? 219 ILE A N   1 
ATOM   1594  C CA  . ILE A 1 219 ? 147.940 139.000 89.358  1.00 26.80  ? 219 ILE A CA  1 
ATOM   1595  C C   . ILE A 1 219 ? 148.115 140.486 89.637  1.00 26.80  ? 219 ILE A C   1 
ATOM   1596  O O   . ILE A 1 219 ? 147.133 141.236 89.673  1.00 26.80  ? 219 ILE A O   1 
ATOM   1597  C CB  . ILE A 1 219 ? 147.701 138.740 87.861  1.00 26.80  ? 219 ILE A CB  1 
ATOM   1598  C CG1 . ILE A 1 219 ? 147.836 137.249 87.552  1.00 26.80  ? 219 ILE A CG1 1 
ATOM   1599  C CG2 . ILE A 1 219 ? 148.670 139.544 87.012  1.00 26.80  ? 219 ILE A CG2 1 
ATOM   1600  C CD1 . ILE A 1 219 ? 147.173 136.831 86.264  1.00 26.80  ? 219 ILE A CD1 1 
ATOM   1601  N N   . GLY A 1 220 ? 149.360 140.907 89.846  1.00 26.21  ? 220 GLY A N   1 
ATOM   1602  C CA  . GLY A 1 220 ? 149.657 142.303 90.097  1.00 26.21  ? 220 GLY A CA  1 
ATOM   1603  C C   . GLY A 1 220 ? 151.039 142.520 90.673  1.00 26.21  ? 220 GLY A C   1 
ATOM   1604  O O   . GLY A 1 220 ? 151.588 141.633 91.332  1.00 26.21  ? 220 GLY A O   1 
ATOM   1605  N N   . SER A 1 221 ? 151.613 143.696 90.434  1.00 26.60  ? 221 SER A N   1 
ATOM   1606  C CA  . SER A 1 221 ? 152.950 143.989 90.927  1.00 26.60  ? 221 SER A CA  1 
ATOM   1607  C C   . SER A 1 221 ? 152.934 144.236 92.431  1.00 26.60  ? 221 SER A C   1 
ATOM   1608  O O   . SER A 1 221 ? 151.964 144.749 92.993  1.00 26.60  ? 221 SER A O   1 
ATOM   1609  C CB  . SER A 1 221 ? 153.533 145.203 90.206  1.00 26.60  ? 221 SER A CB  1 
ATOM   1610  O OG  . SER A 1 221 ? 153.879 144.882 88.871  1.00 26.60  ? 221 SER A OG  1 
ATOM   1611  N N   . ARG A 1 222 ? 154.029 143.862 93.077  1.00 24.40  ? 222 ARG A N   1 
ATOM   1612  C CA  . ARG A 1 222 ? 154.203 143.985 94.514  1.00 24.40  ? 222 ARG A CA  1 
ATOM   1613  C C   . ARG A 1 222 ? 155.607 144.499 94.786  1.00 24.40  ? 222 ARG A C   1 
ATOM   1614  O O   . ARG A 1 222 ? 156.476 144.434 93.910  1.00 24.40  ? 222 ARG A O   1 
ATOM   1615  C CB  . ARG A 1 222 ? 153.974 142.639 95.216  1.00 24.40  ? 222 ARG A CB  1 
ATOM   1616  C CG  . ARG A 1 222 ? 152.510 142.267 95.369  1.00 24.40  ? 222 ARG A CG  1 
ATOM   1617  C CD  . ARG A 1 222 ? 152.298 140.785 95.152  1.00 24.40  ? 222 ARG A CD  1 
ATOM   1618  N NE  . ARG A 1 222 ? 150.900 140.450 94.916  1.00 24.40  ? 222 ARG A NE  1 
ATOM   1619  C CZ  . ARG A 1 222 ? 150.458 139.787 93.857  1.00 24.40  ? 222 ARG A CZ  1 
ATOM   1620  N NH1 . ARG A 1 222 ? 151.280 139.386 92.902  1.00 24.40  ? 222 ARG A NH1 1 
ATOM   1621  N NH2 . ARG A 1 222 ? 149.160 139.519 93.753  1.00 24.40  ? 222 ARG A NH2 1 
ATOM   1622  N N   . PRO A 1 223 ? 155.854 145.043 95.980  1.00 25.60  ? 223 PRO A N   1 
ATOM   1623  C CA  . PRO A 1 223 ? 157.212 145.493 96.310  1.00 25.60  ? 223 PRO A CA  1 
ATOM   1624  C C   . PRO A 1 223 ? 158.209 144.346 96.252  1.00 25.60  ? 223 PRO A C   1 
ATOM   1625  O O   . PRO A 1 223 ? 157.899 143.210 96.612  1.00 25.60  ? 223 PRO A O   1 
ATOM   1626  C CB  . PRO A 1 223 ? 157.069 146.041 97.733  1.00 25.60  ? 223 PRO A CB  1 
ATOM   1627  C CG  . PRO A 1 223 ? 155.634 146.377 97.873  1.00 25.60  ? 223 PRO A CG  1 
ATOM   1628  C CD  . PRO A 1 223 ? 154.885 145.393 97.033  1.00 25.60  ? 223 PRO A CD  1 
ATOM   1629  N N   . TRP A 1 224 ? 159.418 144.656 95.791  1.00 27.97  ? 224 TRP A N   1 
ATOM   1630  C CA  . TRP A 1 224 ? 160.453 143.640 95.665  1.00 27.97  ? 224 TRP A CA  1 
ATOM   1631  C C   . TRP A 1 224 ? 160.922 143.173 97.037  1.00 27.97  ? 224 TRP A C   1 
ATOM   1632  O O   . TRP A 1 224 ? 161.272 143.986 97.897  1.00 27.97  ? 224 TRP A O   1 
ATOM   1633  C CB  . TRP A 1 224 ? 161.639 144.178 94.867  1.00 27.97  ? 224 TRP A CB  1 
ATOM   1634  C CG  . TRP A 1 224 ? 161.509 143.996 93.393  1.00 27.97  ? 224 TRP A CG  1 
ATOM   1635  C CD1 . TRP A 1 224 ? 160.356 143.981 92.666  1.00 27.97  ? 224 TRP A CD1 1 
ATOM   1636  C CD2 . TRP A 1 224 ? 162.573 143.776 92.463  1.00 27.97  ? 224 TRP A CD2 1 
ATOM   1637  N NE1 . TRP A 1 224 ? 160.637 143.780 91.338  1.00 27.97  ? 224 TRP A NE1 1 
ATOM   1638  C CE2 . TRP A 1 224 ? 161.992 143.650 91.187  1.00 27.97  ? 224 TRP A CE2 1 
ATOM   1639  C CE3 . TRP A 1 224 ? 163.961 143.680 92.584  1.00 27.97  ? 224 TRP A CE3 1 
ATOM   1640  C CZ2 . TRP A 1 224 ? 162.751 143.430 90.040  1.00 27.97  ? 224 TRP A CZ2 1 
ATOM   1641  C CZ3 . TRP A 1 224 ? 164.712 143.463 91.445  1.00 27.97  ? 224 TRP A CZ3 1 
ATOM   1642  C CH2 . TRP A 1 224 ? 164.106 143.340 90.190  1.00 27.97  ? 224 TRP A CH2 1 
ATOM   1643  N N   . VAL A 1 225 ? 160.936 141.858 97.234  1.00 24.54  ? 225 VAL A N   1 
ATOM   1644  C CA  . VAL A 1 225 ? 161.466 141.235 98.440  1.00 24.54  ? 225 VAL A CA  1 
ATOM   1645  C C   . VAL A 1 225 ? 162.447 140.163 97.989  1.00 24.54  ? 225 VAL A C   1 
ATOM   1646  O O   . VAL A 1 225 ? 162.035 139.129 97.449  1.00 24.54  ? 225 VAL A O   1 
ATOM   1647  C CB  . VAL A 1 225 ? 160.366 140.635 99.325  1.00 24.54  ? 225 VAL A CB  1 
ATOM   1648  C CG1 . VAL A 1 225 ? 160.979 139.927 100.517 1.00 24.54  ? 225 VAL A CG1 1 
ATOM   1649  C CG2 . VAL A 1 225 ? 159.409 141.718 99.787  1.00 24.54  ? 225 VAL A CG2 1 
ATOM   1650  N N   . ARG A 1 226 ? 163.740 140.409 98.206  1.00 24.58  ? 226 ARG A N   1 
ATOM   1651  C CA  . ARG A 1 226 ? 164.810 139.520 97.755  1.00 24.58  ? 226 ARG A CA  1 
ATOM   1652  C C   . ARG A 1 226 ? 164.763 139.298 96.246  1.00 24.58  ? 226 ARG A C   1 
ATOM   1653  O O   . ARG A 1 226 ? 165.104 138.220 95.755  1.00 24.58  ? 226 ARG A O   1 
ATOM   1654  C CB  . ARG A 1 226 ? 164.777 138.181 98.499  1.00 24.58  ? 226 ARG A CB  1 
ATOM   1655  C CG  . ARG A 1 226 ? 165.165 138.282 99.965  1.00 24.58  ? 226 ARG A CG  1 
ATOM   1656  C CD  . ARG A 1 226 ? 165.028 136.946 100.674 1.00 24.58  ? 226 ARG A CD  1 
ATOM   1657  N NE  . ARG A 1 226 ? 163.644 136.643 101.018 1.00 24.58  ? 226 ARG A NE  1 
ATOM   1658  C CZ  . ARG A 1 226 ? 162.983 137.191 102.028 1.00 24.58  ? 226 ARG A CZ  1 
ATOM   1659  N NH1 . ARG A 1 226 ? 163.551 138.082 102.822 1.00 24.58  ? 226 ARG A NH1 1 
ATOM   1660  N NH2 . ARG A 1 226 ? 161.722 136.833 102.249 1.00 24.58  ? 226 ARG A NH2 1 
ATOM   1661  N N   . GLY A 1 227 ? 164.342 140.317 95.502  1.00 27.07  ? 227 GLY A N   1 
ATOM   1662  C CA  . GLY A 1 227 ? 164.343 140.266 94.056  1.00 27.07  ? 227 GLY A CA  1 
ATOM   1663  C C   . GLY A 1 227 ? 163.074 139.759 93.409  1.00 27.07  ? 227 GLY A C   1 
ATOM   1664  O O   . GLY A 1 227 ? 163.042 139.625 92.180  1.00 27.07  ? 227 GLY A O   1 
ATOM   1665  N N   . GLN A 1 228 ? 162.030 139.477 94.183  1.00 25.50  ? 228 GLN A N   1 
ATOM   1666  C CA  . GLN A 1 228 ? 160.807 138.880 93.662  1.00 25.50  ? 228 GLN A CA  1 
ATOM   1667  C C   . GLN A 1 228 ? 159.640 139.840 93.837  1.00 25.50  ? 228 GLN A C   1 
ATOM   1668  O O   . GLN A 1 228 ? 159.433 140.383 94.927  1.00 25.50  ? 228 GLN A O   1 
ATOM   1669  C CB  . GLN A 1 228 ? 160.500 137.554 94.362  1.00 25.50  ? 228 GLN A CB  1 
ATOM   1670  C CG  . GLN A 1 228 ? 161.627 136.542 94.300  1.00 25.50  ? 228 GLN A CG  1 
ATOM   1671  C CD  . GLN A 1 228 ? 162.012 136.182 92.880  1.00 25.50  ? 228 GLN A CD  1 
ATOM   1672  O OE1 . GLN A 1 228 ? 161.158 136.069 92.003  1.00 25.50  ? 228 GLN A OE1 1 
ATOM   1673  N NE2 . GLN A 1 228 ? 163.305 135.999 92.648  1.00 25.50  ? 228 GLN A NE2 1 
ATOM   1674  N N   . SER A 1 229 ? 158.882 140.042 92.763  1.00 24.60  ? 229 SER A N   1 
ATOM   1675  C CA  . SER A 1 229 ? 157.660 140.832 92.797  1.00 24.60  ? 229 SER A CA  1 
ATOM   1676  C C   . SER A 1 229 ? 156.409 139.976 92.947  1.00 24.60  ? 229 SER A C   1 
ATOM   1677  O O   . SER A 1 229 ? 155.301 140.518 92.944  1.00 24.60  ? 229 SER A O   1 
ATOM   1678  C CB  . SER A 1 229 ? 157.550 141.687 91.533  1.00 24.60  ? 229 SER A CB  1 
ATOM   1679  O OG  . SER A 1 229 ? 156.331 142.405 91.511  1.00 24.60  ? 229 SER A OG  1 
ATOM   1680  N N   . SER A 1 230 ? 156.560 138.663 93.077  1.00 23.06  ? 230 SER A N   1 
ATOM   1681  C CA  . SER A 1 230 ? 155.445 137.744 93.250  1.00 23.06  ? 230 SER A CA  1 
ATOM   1682  C C   . SER A 1 230 ? 155.379 137.259 94.694  1.00 23.06  ? 230 SER A C   1 
ATOM   1683  O O   . SER A 1 230 ? 156.301 137.454 95.487  1.00 23.06  ? 230 SER A O   1 
ATOM   1684  C CB  . SER A 1 230 ? 155.578 136.557 92.293  1.00 23.06  ? 230 SER A CB  1 
ATOM   1685  O OG  . SER A 1 230 ? 155.677 136.991 90.951  1.00 23.06  ? 230 SER A OG  1 
ATOM   1686  N N   . ARG A 1 231 ? 154.264 136.611 95.029  1.00 21.70  ? 231 ARG A N   1 
ATOM   1687  C CA  . ARG A 1 231 ? 154.046 136.099 96.374  1.00 21.70  ? 231 ARG A CA  1 
ATOM   1688  C C   . ARG A 1 231 ? 153.501 134.680 96.294  1.00 21.70  ? 231 ARG A C   1 
ATOM   1689  O O   . ARG A 1 231 ? 153.194 134.164 95.217  1.00 21.70  ? 231 ARG A O   1 
ATOM   1690  C CB  . ARG A 1 231 ? 153.085 136.990 97.171  1.00 21.70  ? 231 ARG A CB  1 
ATOM   1691  C CG  . ARG A 1 231 ? 153.582 138.406 97.395  1.00 21.70  ? 231 ARG A CG  1 
ATOM   1692  C CD  . ARG A 1 231 ? 154.779 138.455 98.321  1.00 21.70  ? 231 ARG A CD  1 
ATOM   1693  N NE  . ARG A 1 231 ? 155.164 139.828 98.625  1.00 21.70  ? 231 ARG A NE  1 
ATOM   1694  C CZ  . ARG A 1 231 ? 156.065 140.524 97.945  1.00 21.70  ? 231 ARG A CZ  1 
ATOM   1695  N NH1 . ARG A 1 231 ? 156.699 140.007 96.906  1.00 21.70  ? 231 ARG A NH1 1 
ATOM   1696  N NH2 . ARG A 1 231 ? 156.336 141.772 98.316  1.00 21.70  ? 231 ARG A NH2 1 
ATOM   1697  N N   . ILE A 1 232 ? 153.391 134.048 97.461  1.00 19.35  ? 232 ILE A N   1 
ATOM   1698  C CA  . ILE A 1 232 ? 152.830 132.709 97.600  1.00 19.35  ? 232 ILE A CA  1 
ATOM   1699  C C   . ILE A 1 232 ? 151.967 132.690 98.854  1.00 19.35  ? 232 ILE A C   1 
ATOM   1700  O O   . ILE A 1 232 ? 152.386 133.186 99.905  1.00 19.35  ? 232 ILE A O   1 
ATOM   1701  C CB  . ILE A 1 232 ? 153.933 131.633 97.677  1.00 19.35  ? 232 ILE A CB  1 
ATOM   1702  C CG1 . ILE A 1 232 ? 154.481 131.327 96.283  1.00 19.35  ? 232 ILE A CG1 1 
ATOM   1703  C CG2 . ILE A 1 232 ? 153.416 130.362 98.328  1.00 19.35  ? 232 ILE A CG2 1 
ATOM   1704  C CD1 . ILE A 1 232 ? 155.590 130.305 96.276  1.00 19.35  ? 232 ILE A CD1 1 
ATOM   1705  N N   . SER A 1 233 ? 150.766 132.130 98.749  1.00 19.08  ? 233 SER A N   1 
ATOM   1706  C CA  . SER A 1 233 ? 149.856 132.003 99.879  1.00 19.08  ? 233 SER A CA  1 
ATOM   1707  C C   . SER A 1 233 ? 149.885 130.572 100.397 1.00 19.08  ? 233 SER A C   1 
ATOM   1708  O O   . SER A 1 233 ? 150.020 129.627 99.617  1.00 19.08  ? 233 SER A O   1 
ATOM   1709  C CB  . SER A 1 233 ? 148.430 132.391 99.487  1.00 19.08  ? 233 SER A CB  1 
ATOM   1710  O OG  . SER A 1 233 ? 148.323 133.786 99.276  1.00 19.08  ? 233 SER A OG  1 
ATOM   1711  N N   . ILE A 1 234 ? 149.758 130.415 101.712 1.00 17.62  ? 234 ILE A N   1 
ATOM   1712  C CA  . ILE A 1 234 ? 149.904 129.125 102.377 1.00 17.62  ? 234 ILE A CA  1 
ATOM   1713  C C   . ILE A 1 234 ? 148.569 128.732 102.993 1.00 17.62  ? 234 ILE A C   1 
ATOM   1714  O O   . ILE A 1 234 ? 147.955 129.523 103.720 1.00 17.62  ? 234 ILE A O   1 
ATOM   1715  C CB  . ILE A 1 234 ? 151.012 129.165 103.445 1.00 17.62  ? 234 ILE A CB  1 
ATOM   1716  C CG1 . ILE A 1 234 ? 152.357 129.515 102.806 1.00 17.62  ? 234 ILE A CG1 1 
ATOM   1717  C CG2 . ILE A 1 234 ? 151.100 127.838 104.178 1.00 17.62  ? 234 ILE A CG2 1 
ATOM   1718  C CD1 . ILE A 1 234 ? 152.910 128.434 101.907 1.00 17.62  ? 234 ILE A CD1 1 
ATOM   1719  N N   . TYR A 1 235 ? 148.123 127.510 102.703 1.00 18.16  ? 235 TYR A N   1 
ATOM   1720  C CA  . TYR A 1 235 ? 146.881 126.967 103.232 1.00 18.16  ? 235 TYR A CA  1 
ATOM   1721  C C   . TYR A 1 235 ? 147.147 125.590 103.824 1.00 18.16  ? 235 TYR A C   1 
ATOM   1722  O O   . TYR A 1 235 ? 148.172 124.963 103.548 1.00 18.16  ? 235 TYR A O   1 
ATOM   1723  C CB  . TYR A 1 235 ? 145.801 126.880 102.146 1.00 18.16  ? 235 TYR A CB  1 
ATOM   1724  C CG  . TYR A 1 235 ? 145.504 128.203 101.479 1.00 18.16  ? 235 TYR A CG  1 
ATOM   1725  C CD1 . TYR A 1 235 ? 144.541 129.059 101.991 1.00 18.16  ? 235 TYR A CD1 1 
ATOM   1726  C CD2 . TYR A 1 235 ? 146.192 128.599 100.340 1.00 18.16  ? 235 TYR A CD2 1 
ATOM   1727  C CE1 . TYR A 1 235 ? 144.271 130.269 101.390 1.00 18.16  ? 235 TYR A CE1 1 
ATOM   1728  C CE2 . TYR A 1 235 ? 145.927 129.807 99.732  1.00 18.16  ? 235 TYR A CE2 1 
ATOM   1729  C CZ  . TYR A 1 235 ? 144.966 130.638 100.262 1.00 18.16  ? 235 TYR A CZ  1 
ATOM   1730  O OH  . TYR A 1 235 ? 144.694 131.844 99.661  1.00 18.16  ? 235 TYR A OH  1 
ATOM   1731  N N   . TRP A 1 236 ? 146.215 125.122 104.653 1.00 19.88  ? 236 TRP A N   1 
ATOM   1732  C CA  . TRP A 1 236 ? 146.369 123.836 105.318 1.00 19.88  ? 236 TRP A CA  1 
ATOM   1733  C C   . TRP A 1 236 ? 145.042 123.090 105.328 1.00 19.88  ? 236 TRP A C   1 
ATOM   1734  O O   . TRP A 1 236 ? 143.966 123.687 105.267 1.00 19.88  ? 236 TRP A O   1 
ATOM   1735  C CB  . TRP A 1 236 ? 146.914 124.001 106.746 1.00 19.88  ? 236 TRP A CB  1 
ATOM   1736  C CG  . TRP A 1 236 ? 145.905 124.423 107.773 1.00 19.88  ? 236 TRP A CG  1 
ATOM   1737  C CD1 . TRP A 1 236 ? 145.054 123.616 108.471 1.00 19.88  ? 236 TRP A CD1 1 
ATOM   1738  C CD2 . TRP A 1 236 ? 145.659 125.756 108.236 1.00 19.88  ? 236 TRP A CD2 1 
ATOM   1739  N NE1 . TRP A 1 236 ? 144.287 124.363 109.329 1.00 19.88  ? 236 TRP A NE1 1 
ATOM   1740  C CE2 . TRP A 1 236 ? 144.640 125.681 109.205 1.00 19.88  ? 236 TRP A CE2 1 
ATOM   1741  C CE3 . TRP A 1 236 ? 146.198 127.007 107.921 1.00 19.88  ? 236 TRP A CE3 1 
ATOM   1742  C CZ2 . TRP A 1 236 ? 144.150 126.807 109.861 1.00 19.88  ? 236 TRP A CZ2 1 
ATOM   1743  C CZ3 . TRP A 1 236 ? 145.710 128.122 108.574 1.00 19.88  ? 236 TRP A CZ3 1 
ATOM   1744  C CH2 . TRP A 1 236 ? 144.696 128.015 109.531 1.00 19.88  ? 236 TRP A CH2 1 
ATOM   1745  N N   . THR A 1 237 ? 145.140 121.762 105.400 1.00 20.61  ? 237 THR A N   1 
ATOM   1746  C CA  . THR A 1 237 ? 143.986 120.872 105.394 1.00 20.61  ? 237 THR A CA  1 
ATOM   1747  C C   . THR A 1 237 ? 144.252 119.701 106.329 1.00 20.61  ? 237 THR A C   1 
ATOM   1748  O O   . THR A 1 237 ? 145.375 119.194 106.392 1.00 20.61  ? 237 THR A O   1 
ATOM   1749  C CB  . THR A 1 237 ? 143.686 120.352 103.980 1.00 20.61  ? 237 THR A CB  1 
ATOM   1750  O OG1 . THR A 1 237 ? 143.649 121.450 103.062 1.00 20.61  ? 237 THR A OG1 1 
ATOM   1751  C CG2 . THR A 1 237 ? 142.351 119.629 103.941 1.00 20.61  ? 237 THR A CG2 1 
ATOM   1752  N N   . ILE A 1 238 ? 143.218 119.273 107.049 1.00 24.12  ? 238 ILE A N   1 
ATOM   1753  C CA  . ILE A 1 238 ? 143.303 118.151 107.978 1.00 24.12  ? 238 ILE A CA  1 
ATOM   1754  C C   . ILE A 1 238 ? 142.391 117.039 107.477 1.00 24.12  ? 238 ILE A C   1 
ATOM   1755  O O   . ILE A 1 238 ? 141.233 117.291 107.126 1.00 24.12  ? 238 ILE A O   1 
ATOM   1756  C CB  . ILE A 1 238 ? 142.924 118.567 109.410 1.00 24.12  ? 238 ILE A CB  1 
ATOM   1757  C CG1 . ILE A 1 238 ? 144.039 119.410 110.027 1.00 24.12  ? 238 ILE A CG1 1 
ATOM   1758  C CG2 . ILE A 1 238 ? 142.655 117.347 110.274 1.00 24.12  ? 238 ILE A CG2 1 
ATOM   1759  C CD1 . ILE A 1 238 ? 143.671 120.030 111.346 1.00 24.12  ? 238 ILE A CD1 1 
ATOM   1760  N N   . VAL A 1 239 ? 142.916 115.816 107.440 1.00 25.11  ? 239 VAL A N   1 
ATOM   1761  C CA  . VAL A 1 239 ? 142.181 114.645 106.971 1.00 25.11  ? 239 VAL A CA  1 
ATOM   1762  C C   . VAL A 1 239 ? 142.025 113.680 108.138 1.00 25.11  ? 239 VAL A C   1 
ATOM   1763  O O   . VAL A 1 239 ? 143.021 113.241 108.726 1.00 25.11  ? 239 VAL A O   1 
ATOM   1764  C CB  . VAL A 1 239 ? 142.889 113.965 105.788 1.00 25.11  ? 239 VAL A CB  1 
ATOM   1765  C CG1 . VAL A 1 239 ? 141.998 112.902 105.176 1.00 25.11  ? 239 VAL A CG1 1 
ATOM   1766  C CG2 . VAL A 1 239 ? 143.290 114.994 104.745 1.00 25.11  ? 239 VAL A CG2 1 
ATOM   1767  N N   . LYS A 1 240 ? 140.779 113.350 108.470 1.00 29.07  ? 240 LYS A N   1 
ATOM   1768  C CA  . LYS A 1 240 ? 140.470 112.406 109.531 1.00 29.07  ? 240 LYS A CA  1 
ATOM   1769  C C   . LYS A 1 240 ? 140.710 110.972 109.066 1.00 29.07  ? 240 LYS A C   1 
ATOM   1770  O O   . LYS A 1 240 ? 140.717 110.693 107.866 1.00 29.07  ? 240 LYS A O   1 
ATOM   1771  C CB  . LYS A 1 240 ? 139.021 112.579 109.974 1.00 29.07  ? 240 LYS A CB  1 
ATOM   1772  C CG  . LYS A 1 240 ? 138.771 113.814 110.818 1.00 29.07  ? 240 LYS A CG  1 
ATOM   1773  C CD  . LYS A 1 240 ? 139.406 113.669 112.189 1.00 29.07  ? 240 LYS A CD  1 
ATOM   1774  C CE  . LYS A 1 240 ? 139.023 114.818 113.101 1.00 29.07  ? 240 LYS A CE  1 
ATOM   1775  N NZ  . LYS A 1 240 ? 137.577 114.789 113.452 1.00 29.07  ? 240 LYS A NZ  1 
ATOM   1776  N N   . PRO A 1 241 ? 140.927 110.043 110.000 1.00 29.94  ? 241 PRO A N   1 
ATOM   1777  C CA  . PRO A 1 241 ? 141.092 108.637 109.608 1.00 29.94  ? 241 PRO A CA  1 
ATOM   1778  C C   . PRO A 1 241 ? 139.858 108.115 108.889 1.00 29.94  ? 241 PRO A C   1 
ATOM   1779  O O   . PRO A 1 241 ? 138.723 108.411 109.266 1.00 29.94  ? 241 PRO A O   1 
ATOM   1780  C CB  . PRO A 1 241 ? 141.313 107.918 110.943 1.00 29.94  ? 241 PRO A CB  1 
ATOM   1781  C CG  . PRO A 1 241 ? 141.796 108.971 111.869 1.00 29.94  ? 241 PRO A CG  1 
ATOM   1782  C CD  . PRO A 1 241 ? 141.116 110.234 111.448 1.00 29.94  ? 241 PRO A CD  1 
ATOM   1783  N N   . GLY A 1 242 ? 140.092 107.324 107.845 1.00 29.16  ? 242 GLY A N   1 
ATOM   1784  C CA  . GLY A 1 242 ? 139.017 106.824 107.018 1.00 29.16  ? 242 GLY A CA  1 
ATOM   1785  C C   . GLY A 1 242 ? 138.531 107.780 105.953 1.00 29.16  ? 242 GLY A C   1 
ATOM   1786  O O   . GLY A 1 242 ? 137.619 107.424 105.196 1.00 29.16  ? 242 GLY A O   1 
ATOM   1787  N N   . ASP A 1 243 ? 139.105 108.976 105.866 1.00 30.24  ? 243 ASP A N   1 
ATOM   1788  C CA  . ASP A 1 243 ? 138.723 109.968 104.876 1.00 30.24  ? 243 ASP A CA  1 
ATOM   1789  C C   . ASP A 1 243 ? 139.691 109.921 103.696 1.00 30.24  ? 243 ASP A C   1 
ATOM   1790  O O   . ASP A 1 243 ? 140.577 109.068 103.615 1.00 30.24  ? 243 ASP A O   1 
ATOM   1791  C CB  . ASP A 1 243 ? 138.678 111.360 105.507 1.00 30.24  ? 243 ASP A CB  1 
ATOM   1792  C CG  . ASP A 1 243 ? 137.670 112.270 104.841 1.00 30.24  ? 243 ASP A CG  1 
ATOM   1793  O OD1 . ASP A 1 243 ? 137.533 112.199 103.603 1.00 30.24  ? 243 ASP A OD1 1 
ATOM   1794  O OD2 . ASP A 1 243 ? 137.016 113.058 105.555 1.00 30.24  ? 243 ASP A OD2 1 
ATOM   1795  N N   . VAL A 1 244 ? 139.518 110.860 102.767 1.00 28.26  ? 244 VAL A N   1 
ATOM   1796  C CA  . VAL A 1 244 ? 140.298 110.894 101.537 1.00 28.26  ? 244 VAL A CA  1 
ATOM   1797  C C   . VAL A 1 244 ? 140.565 112.345 101.159 1.00 28.26  ? 244 VAL A C   1 
ATOM   1798  O O   . VAL A 1 244 ? 139.762 113.240 101.442 1.00 28.26  ? 244 VAL A O   1 
ATOM   1799  C CB  . VAL A 1 244 ? 139.575 110.135 100.398 1.00 28.26  ? 244 VAL A CB  1 
ATOM   1800  C CG1 . VAL A 1 244 ? 138.282 110.833 100.022 1.00 28.26  ? 244 VAL A CG1 1 
ATOM   1801  C CG2 . VAL A 1 244 ? 140.479 109.967 99.188  1.00 28.26  ? 244 VAL A CG2 1 
ATOM   1802  N N   . LEU A 1 245 ? 141.715 112.577 100.533 1.00 25.45  ? 245 LEU A N   1 
ATOM   1803  C CA  . LEU A 1 245 ? 142.122 113.897 100.069 1.00 25.45  ? 245 LEU A CA  1 
ATOM   1804  C C   . LEU A 1 245 ? 142.181 113.900 98.548  1.00 25.45  ? 245 LEU A C   1 
ATOM   1805  O O   . LEU A 1 245 ? 142.778 113.002 97.947  1.00 25.45  ? 245 LEU A O   1 
ATOM   1806  C CB  . LEU A 1 245 ? 143.487 114.284 100.641 1.00 25.45  ? 245 LEU A CB  1 
ATOM   1807  C CG  . LEU A 1 245 ? 144.008 115.681 100.294 1.00 25.45  ? 245 LEU A CG  1 
ATOM   1808  C CD1 . LEU A 1 245 ? 143.163 116.757 100.955 1.00 25.45  ? 245 LEU A CD1 1 
ATOM   1809  C CD2 . LEU A 1 245 ? 145.470 115.827 100.666 1.00 25.45  ? 245 LEU A CD2 1 
ATOM   1810  N N   . VAL A 1 246 ? 141.567 114.906 97.933  1.00 24.40  ? 246 VAL A N   1 
ATOM   1811  C CA  . VAL A 1 246 ? 141.586 115.085 96.486  1.00 24.40  ? 246 VAL A CA  1 
ATOM   1812  C C   . VAL A 1 246 ? 142.097 116.487 96.187  1.00 24.40  ? 246 VAL A C   1 
ATOM   1813  O O   . VAL A 1 246 ? 141.654 117.459 96.809  1.00 24.40  ? 246 VAL A O   1 
ATOM   1814  C CB  . VAL A 1 246 ? 140.195 114.862 95.862  1.00 24.40  ? 246 VAL A CB  1 
ATOM   1815  C CG1 . VAL A 1 246 ? 140.230 115.136 94.368  1.00 24.40  ? 246 VAL A CG1 1 
ATOM   1816  C CG2 . VAL A 1 246 ? 139.720 113.445 96.124  1.00 24.40  ? 246 VAL A CG2 1 
ATOM   1817  N N   . ILE A 1 247 ? 143.034 116.587 95.249  1.00 23.32  ? 247 ILE A N   1 
ATOM   1818  C CA  . ILE A 1 247 ? 143.582 117.864 94.807  1.00 23.32  ? 247 ILE A CA  1 
ATOM   1819  C C   . ILE A 1 247 ? 143.294 118.007 93.321  1.00 23.32  ? 247 ILE A C   1 
ATOM   1820  O O   . ILE A 1 247 ? 143.707 117.162 92.518  1.00 23.32  ? 247 ILE A O   1 
ATOM   1821  C CB  . ILE A 1 247 ? 145.089 117.972 95.086  1.00 23.32  ? 247 ILE A CB  1 
ATOM   1822  C CG1 . ILE A 1 247 ? 145.370 117.811 96.581  1.00 23.32  ? 247 ILE A CG1 1 
ATOM   1823  C CG2 . ILE A 1 247 ? 145.630 119.300 94.584  1.00 23.32  ? 247 ILE A CG2 1 
ATOM   1824  C CD1 . ILE A 1 247 ? 146.818 117.534 96.900  1.00 23.32  ? 247 ILE A CD1 1 
ATOM   1825  N N   . ASN A 1 248 ? 142.589 119.075 92.958  1.00 25.35  ? 248 ASN A N   1 
ATOM   1826  C CA  . ASN A 1 248 ? 142.263 119.386 91.572  1.00 25.35  ? 248 ASN A CA  1 
ATOM   1827  C C   . ASN A 1 248 ? 142.820 120.767 91.263  1.00 25.35  ? 248 ASN A C   1 
ATOM   1828  O O   . ASN A 1 248 ? 142.503 121.734 91.962  1.00 25.35  ? 248 ASN A O   1 
ATOM   1829  C CB  . ASN A 1 248 ? 140.751 119.341 91.341  1.00 25.35  ? 248 ASN A CB  1 
ATOM   1830  C CG  . ASN A 1 248 ? 140.384 119.294 89.873  1.00 25.35  ? 248 ASN A CG  1 
ATOM   1831  O OD1 . ASN A 1 248 ? 140.188 120.328 89.238  1.00 25.35  ? 248 ASN A OD1 1 
ATOM   1832  N ND2 . ASN A 1 248 ? 140.283 118.090 89.327  1.00 25.35  ? 248 ASN A ND2 1 
ATOM   1833  N N   . SER A 1 249 ? 143.650 120.860 90.227  1.00 25.37  ? 249 SER A N   1 
ATOM   1834  C CA  . SER A 1 249 ? 144.348 122.103 89.939  1.00 25.37  ? 249 SER A CA  1 
ATOM   1835  C C   . SER A 1 249 ? 144.408 122.356 88.442  1.00 25.37  ? 249 SER A C   1 
ATOM   1836  O O   . SER A 1 249 ? 144.572 121.427 87.647  1.00 25.37  ? 249 SER A O   1 
ATOM   1837  C CB  . SER A 1 249 ? 145.770 122.087 90.511  1.00 25.37  ? 249 SER A CB  1 
ATOM   1838  O OG  . SER A 1 249 ? 146.472 123.263 90.154  1.00 25.37  ? 249 SER A OG  1 
ATOM   1839  N N   . ASN A 1 250 ? 144.274 123.630 88.071  1.00 28.73  ? 250 ASN A N   1 
ATOM   1840  C CA  . ASN A 1 250 ? 144.480 124.087 86.706  1.00 28.73  ? 250 ASN A CA  1 
ATOM   1841  C C   . ASN A 1 250 ? 145.790 124.839 86.523  1.00 28.73  ? 250 ASN A C   1 
ATOM   1842  O O   . ASN A 1 250 ? 146.207 125.053 85.381  1.00 28.73  ? 250 ASN A O   1 
ATOM   1843  C CB  . ASN A 1 250 ? 143.319 124.994 86.271  1.00 28.73  ? 250 ASN A CB  1 
ATOM   1844  C CG  . ASN A 1 250 ? 142.982 124.850 84.806  1.00 28.73  ? 250 ASN A CG  1 
ATOM   1845  O OD1 . ASN A 1 250 ? 143.309 123.844 84.178  1.00 28.73  ? 250 ASN A OD1 1 
ATOM   1846  N ND2 . ASN A 1 250 ? 142.319 125.856 84.251  1.00 28.73  ? 250 ASN A ND2 1 
ATOM   1847  N N   . GLY A 1 251 ? 146.435 125.237 87.609  1.00 24.63  ? 251 GLY A N   1 
ATOM   1848  C CA  . GLY A 1 251 ? 147.678 125.978 87.549  1.00 24.63  ? 251 GLY A CA  1 
ATOM   1849  C C   . GLY A 1 251 ? 147.937 126.680 88.860  1.00 24.63  ? 251 GLY A C   1 
ATOM   1850  O O   . GLY A 1 251 ? 147.073 126.760 89.733  1.00 24.63  ? 251 GLY A O   1 
ATOM   1851  N N   . ASN A 1 252 ? 149.168 127.182 88.989  1.00 23.90  ? 252 ASN A N   1 
ATOM   1852  C CA  . ASN A 1 252 ? 149.603 127.971 90.143  1.00 23.90  ? 252 ASN A CA  1 
ATOM   1853  C C   . ASN A 1 252 ? 149.601 127.167 91.441  1.00 23.90  ? 252 ASN A C   1 
ATOM   1854  O O   . ASN A 1 252 ? 149.434 127.733 92.522  1.00 23.90  ? 252 ASN A O   1 
ATOM   1855  C CB  . ASN A 1 252 ? 148.749 129.233 90.317  1.00 23.90  ? 252 ASN A CB  1 
ATOM   1856  C CG  . ASN A 1 252 ? 148.730 130.102 89.080  1.00 23.90  ? 252 ASN A CG  1 
ATOM   1857  O OD1 . ASN A 1 252 ? 148.071 129.781 88.093  1.00 23.90  ? 252 ASN A OD1 1 
ATOM   1858  N ND2 . ASN A 1 252 ? 149.450 131.213 89.128  1.00 23.90  ? 252 ASN A ND2 1 
ATOM   1859  N N   . LEU A 1 253 ? 149.799 125.855 91.362  1.00 22.33  ? 253 LEU A N   1 
ATOM   1860  C CA  . LEU A 1 253 ? 149.737 124.986 92.531  1.00 22.33  ? 253 LEU A CA  1 
ATOM   1861  C C   . LEU A 1 253 ? 151.132 124.745 93.093  1.00 22.33  ? 253 LEU A C   1 
ATOM   1862  O O   . LEU A 1 253 ? 152.052 124.381 92.353  1.00 22.33  ? 253 LEU A O   1 
ATOM   1863  C CB  . LEU A 1 253 ? 149.077 123.651 92.183  1.00 22.33  ? 253 LEU A CB  1 
ATOM   1864  C CG  . LEU A 1 253 ? 149.244 122.524 93.206  1.00 22.33  ? 253 LEU A CG  1 
ATOM   1865  C CD1 . LEU A 1 253 ? 148.339 122.731 94.408  1.00 22.33  ? 253 LEU A CD1 1 
ATOM   1866  C CD2 . LEU A 1 253 ? 148.985 121.171 92.567  1.00 22.33  ? 253 LEU A CD2 1 
ATOM   1867  N N   . ILE A 1 254 ? 151.281 124.950 94.398  1.00 20.70  ? 254 ILE A N   1 
ATOM   1868  C CA  . ILE A 1 254 ? 152.482 124.572 95.133  1.00 20.70  ? 254 ILE A CA  1 
ATOM   1869  C C   . ILE A 1 254 ? 152.135 123.290 95.881  1.00 20.70  ? 254 ILE A C   1 
ATOM   1870  O O   . ILE A 1 254 ? 151.521 123.325 96.950  1.00 20.70  ? 254 ILE A O   1 
ATOM   1871  C CB  . ILE A 1 254 ? 152.948 125.681 96.080  1.00 20.70  ? 254 ILE A CB  1 
ATOM   1872  C CG1 . ILE A 1 254 ? 152.980 127.030 95.356  1.00 20.70  ? 254 ILE A CG1 1 
ATOM   1873  C CG2 . ILE A 1 254 ? 154.313 125.348 96.662  1.00 20.70  ? 254 ILE A CG2 1 
ATOM   1874  C CD1 . ILE A 1 254 ? 154.075 127.152 94.326  1.00 20.70  ? 254 ILE A CD1 1 
ATOM   1875  N N   . ALA A 1 255 ? 152.526 122.156 95.318  1.00 21.69  ? 255 ALA A N   1 
ATOM   1876  C CA  . ALA A 1 255 ? 152.068 120.864 95.796  1.00 21.69  ? 255 ALA A CA  1 
ATOM   1877  C C   . ALA A 1 255 ? 152.760 120.467 97.098  1.00 21.69  ? 255 ALA A C   1 
ATOM   1878  O O   . ALA A 1 255 ? 153.936 120.777 97.307  1.00 21.69  ? 255 ALA A O   1 
ATOM   1879  C CB  . ALA A 1 255 ? 152.319 119.795 94.741  1.00 21.69  ? 255 ALA A CB  1 
ATOM   1880  N N   . PRO A 1 256 ? 152.051 119.779 97.987  1.00 22.11  ? 256 PRO A N   1 
ATOM   1881  C CA  . PRO A 1 256 ? 152.694 119.215 99.175  1.00 22.11  ? 256 PRO A CA  1 
ATOM   1882  C C   . PRO A 1 256 ? 153.512 117.979 98.832  1.00 22.11  ? 256 PRO A C   1 
ATOM   1883  O O   . PRO A 1 256 ? 153.290 117.305 97.825  1.00 22.11  ? 256 PRO A O   1 
ATOM   1884  C CB  . PRO A 1 256 ? 151.512 118.858 100.081 1.00 22.11  ? 256 PRO A CB  1 
ATOM   1885  C CG  . PRO A 1 256 ? 150.393 118.602 99.143  1.00 22.11  ? 256 PRO A CG  1 
ATOM   1886  C CD  . PRO A 1 256 ? 150.603 119.504 97.957  1.00 22.11  ? 256 PRO A CD  1 
ATOM   1887  N N   . ARG A 1 257 ? 154.478 117.691 99.700  1.00 20.55  ? 257 ARG A N   1 
ATOM   1888  C CA  . ARG A 1 257 ? 155.323 116.514 99.560  1.00 20.55  ? 257 ARG A CA  1 
ATOM   1889  C C   . ARG A 1 257 ? 154.954 115.406 100.536 1.00 20.55  ? 257 ARG A C   1 
ATOM   1890  O O   . ARG A 1 257 ? 155.552 114.328 100.485 1.00 20.55  ? 257 ARG A O   1 
ATOM   1891  C CB  . ARG A 1 257 ? 156.793 116.898 99.746  1.00 20.55  ? 257 ARG A CB  1 
ATOM   1892  C CG  . ARG A 1 257 ? 157.366 117.728 98.615  1.00 20.55  ? 257 ARG A CG  1 
ATOM   1893  C CD  . ARG A 1 257 ? 158.870 117.843 98.733  1.00 20.55  ? 257 ARG A CD  1 
ATOM   1894  N NE  . ARG A 1 257 ? 159.433 118.752 97.744  1.00 20.55  ? 257 ARG A NE  1 
ATOM   1895  C CZ  . ARG A 1 257 ? 159.869 118.380 96.549  1.00 20.55  ? 257 ARG A CZ  1 
ATOM   1896  N NH1 . ARG A 1 257 ? 159.801 117.121 96.150  1.00 20.55  ? 257 ARG A NH1 1 
ATOM   1897  N NH2 . ARG A 1 257 ? 160.387 119.293 95.735  1.00 20.55  ? 257 ARG A NH2 1 
ATOM   1898  N N   . GLY A 1 258 ? 153.982 115.643 101.411 1.00 19.24  ? 258 GLY A N   1 
ATOM   1899  C CA  . GLY A 1 258 ? 153.625 114.666 102.422 1.00 19.24  ? 258 GLY A CA  1 
ATOM   1900  C C   . GLY A 1 258 ? 152.694 115.290 103.441 1.00 19.24  ? 258 GLY A C   1 
ATOM   1901  O O   . GLY A 1 258 ? 152.020 116.279 103.155 1.00 19.24  ? 258 GLY A O   1 
ATOM   1902  N N   . PHE A 1 259 ? 152.675 114.703 104.635 1.00 20.06  ? 259 PHE A N   1 
ATOM   1903  C CA  . PHE A 1 259 ? 151.805 115.168 105.703 1.00 20.06  ? 259 PHE A CA  1 
ATOM   1904  C C   . PHE A 1 259 ? 152.588 115.297 107.003 1.00 20.06  ? 259 PHE A C   1 
ATOM   1905  O O   . PHE A 1 259 ? 153.645 114.690 107.184 1.00 20.06  ? 259 PHE A O   1 
ATOM   1906  C CB  . PHE A 1 259 ? 150.600 114.232 105.903 1.00 20.06  ? 259 PHE A CB  1 
ATOM   1907  C CG  . PHE A 1 259 ? 150.966 112.851 106.373 1.00 20.06  ? 259 PHE A CG  1 
ATOM   1908  C CD1 . PHE A 1 259 ? 151.295 111.860 105.465 1.00 20.06  ? 259 PHE A CD1 1 
ATOM   1909  C CD2 . PHE A 1 259 ? 150.963 112.539 107.722 1.00 20.06  ? 259 PHE A CD2 1 
ATOM   1910  C CE1 . PHE A 1 259 ? 151.625 110.591 105.894 1.00 20.06  ? 259 PHE A CE1 1 
ATOM   1911  C CE2 . PHE A 1 259 ? 151.293 111.273 108.156 1.00 20.06  ? 259 PHE A CE2 1 
ATOM   1912  C CZ  . PHE A 1 259 ? 151.622 110.297 107.240 1.00 20.06  ? 259 PHE A CZ  1 
ATOM   1913  N N   . PHE A 1 260 ? 152.048 116.112 107.904 1.00 22.19  ? 260 PHE A N   1 
ATOM   1914  C CA  . PHE A 1 260 ? 152.581 116.282 109.248 1.00 22.19  ? 260 PHE A CA  1 
ATOM   1915  C C   . PHE A 1 260 ? 151.724 115.494 110.229 1.00 22.19  ? 260 PHE A C   1 
ATOM   1916  O O   . PHE A 1 260 ? 150.494 115.602 110.209 1.00 22.19  ? 260 PHE A O   1 
ATOM   1917  C CB  . PHE A 1 260 ? 152.603 117.757 109.652 1.00 22.19  ? 260 PHE A CB  1 
ATOM   1918  C CG  . PHE A 1 260 ? 153.737 118.538 109.057 1.00 22.19  ? 260 PHE A CG  1 
ATOM   1919  C CD1 . PHE A 1 260 ? 154.992 118.511 109.637 1.00 22.19  ? 260 PHE A CD1 1 
ATOM   1920  C CD2 . PHE A 1 260 ? 153.543 119.310 107.926 1.00 22.19  ? 260 PHE A CD2 1 
ATOM   1921  C CE1 . PHE A 1 260 ? 156.034 119.232 109.094 1.00 22.19  ? 260 PHE A CE1 1 
ATOM   1922  C CE2 . PHE A 1 260 ? 154.581 120.032 107.379 1.00 22.19  ? 260 PHE A CE2 1 
ATOM   1923  C CZ  . PHE A 1 260 ? 155.828 119.994 107.964 1.00 22.19  ? 260 PHE A CZ  1 
ATOM   1924  N N   . LYS A 1 261 ? 152.372 114.709 111.082 1.00 26.81  ? 261 LYS A N   1 
ATOM   1925  C CA  . LYS A 1 261 ? 151.665 113.968 112.119 1.00 26.81  ? 261 LYS A CA  1 
ATOM   1926  C C   . LYS A 1 261 ? 151.327 114.916 113.263 1.00 26.81  ? 261 LYS A C   1 
ATOM   1927  O O   . LYS A 1 261 ? 152.226 115.477 113.898 1.00 26.81  ? 261 LYS A O   1 
ATOM   1928  C CB  . LYS A 1 261 ? 152.515 112.800 112.611 1.00 26.81  ? 261 LYS A CB  1 
ATOM   1929  C CG  . LYS A 1 261 ? 151.745 111.766 113.407 1.00 26.81  ? 261 LYS A CG  1 
ATOM   1930  C CD  . LYS A 1 261 ? 152.618 110.571 113.740 1.00 26.81  ? 261 LYS A CD  1 
ATOM   1931  C CE  . LYS A 1 261 ? 152.958 109.775 112.493 1.00 26.81  ? 261 LYS A CE  1 
ATOM   1932  N NZ  . LYS A 1 261 ? 153.736 108.548 112.814 1.00 26.81  ? 261 LYS A NZ  1 
ATOM   1933  N N   . ILE A 1 262 ? 150.036 115.095 113.527 1.00 28.08  ? 262 ILE A N   1 
ATOM   1934  C CA  . ILE A 1 262 ? 149.559 116.040 114.529 1.00 28.08  ? 262 ILE A CA  1 
ATOM   1935  C C   . ILE A 1 262 ? 149.102 115.270 115.760 1.00 28.08  ? 262 ILE A C   1 
ATOM   1936  O O   . ILE A 1 262 ? 148.343 114.299 115.658 1.00 28.08  ? 262 ILE A O   1 
ATOM   1937  C CB  . ILE A 1 262 ? 148.433 116.935 113.969 1.00 28.08  ? 262 ILE A CB  1 
ATOM   1938  C CG1 . ILE A 1 262 ? 147.899 117.875 115.053 1.00 28.08  ? 262 ILE A CG1 1 
ATOM   1939  C CG2 . ILE A 1 262 ? 147.316 116.103 113.353 1.00 28.08  ? 262 ILE A CG2 1 
ATOM   1940  C CD1 . ILE A 1 262 ? 147.043 119.000 114.515 1.00 28.08  ? 262 ILE A CD1 1 
ATOM   1941  N N   . ARG A 1 263 ? 149.585 115.695 116.922 1.00 31.11  ? 263 ARG A N   1 
ATOM   1942  C CA  . ARG A 1 263 ? 149.285 115.068 118.201 1.00 31.11  ? 263 ARG A CA  1 
ATOM   1943  C C   . ARG A 1 263 ? 148.525 116.043 119.097 1.00 31.11  ? 263 ARG A C   1 
ATOM   1944  O O   . ARG A 1 263 ? 148.273 117.195 118.735 1.00 31.11  ? 263 ARG A O   1 
ATOM   1945  C CB  . ARG A 1 263 ? 150.567 114.587 118.890 1.00 31.11  ? 263 ARG A CB  1 
ATOM   1946  C CG  . ARG A 1 263 ? 151.267 113.430 118.192 1.00 31.11  ? 263 ARG A CG  1 
ATOM   1947  C CD  . ARG A 1 263 ? 152.528 113.019 118.940 1.00 31.11  ? 263 ARG A CD  1 
ATOM   1948  N NE  . ARG A 1 263 ? 153.206 111.890 118.312 1.00 31.11  ? 263 ARG A NE  1 
ATOM   1949  C CZ  . ARG A 1 263 ? 154.151 111.992 117.388 1.00 31.11  ? 263 ARG A CZ  1 
ATOM   1950  N NH1 . ARG A 1 263 ? 154.570 113.168 116.953 1.00 31.11  ? 263 ARG A NH1 1 
ATOM   1951  N NH2 . ARG A 1 263 ? 154.695 110.884 116.892 1.00 31.11  ? 263 ARG A NH2 1 
ATOM   1952  N N   . THR A 1 264 ? 148.154 115.557 120.279 1.00 32.63  ? 264 THR A N   1 
ATOM   1953  C CA  . THR A 1 264 ? 147.480 116.348 121.300 1.00 32.63  ? 264 THR A CA  1 
ATOM   1954  C C   . THR A 1 264 ? 148.311 116.302 122.573 1.00 32.63  ? 264 THR A C   1 
ATOM   1955  O O   . THR A 1 264 ? 148.674 115.218 123.040 1.00 32.63  ? 264 THR A O   1 
ATOM   1956  C CB  . THR A 1 264 ? 146.068 115.820 121.573 1.00 32.63  ? 264 THR A CB  1 
ATOM   1957  O OG1 . THR A 1 264 ? 145.376 115.633 120.332 1.00 32.63  ? 264 THR A OG1 1 
ATOM   1958  C CG2 . THR A 1 264 ? 145.290 116.794 122.441 1.00 32.63  ? 264 THR A CG2 1 
ATOM   1959  N N   . GLY A 1 265 ? 148.606 117.466 123.131 1.00 30.88  ? 265 GLY A N   1 
ATOM   1960  C CA  . GLY A 1 265 ? 149.465 117.514 124.291 1.00 30.88  ? 265 GLY A CA  1 
ATOM   1961  C C   . GLY A 1 265 ? 149.488 118.881 124.931 1.00 30.88  ? 265 GLY A C   1 
ATOM   1962  O O   . GLY A 1 265 ? 148.617 119.717 124.687 1.00 30.88  ? 265 GLY A O   1 
ATOM   1963  N N   . ARG A 1 266 ? 150.507 119.096 125.758 1.00 31.55  ? 266 ARG A N   1 
ATOM   1964  C CA  . ARG A 1 266 ? 150.646 120.300 126.569 1.00 31.55  ? 266 ARG A CA  1 
ATOM   1965  C C   . ARG A 1 266 ? 151.807 121.176 126.104 1.00 31.55  ? 266 ARG A C   1 
ATOM   1966  O O   . ARG A 1 266 ? 152.539 121.745 126.915 1.00 31.55  ? 266 ARG A O   1 
ATOM   1967  C CB  . ARG A 1 266 ? 150.813 119.928 128.038 1.00 31.55  ? 266 ARG A CB  1 
ATOM   1968  C CG  . ARG A 1 266 ? 151.743 118.751 128.269 1.00 31.55  ? 266 ARG A CG  1 
ATOM   1969  C CD  . ARG A 1 266 ? 152.103 118.608 129.735 1.00 31.55  ? 266 ARG A CD  1 
ATOM   1970  N NE  . ARG A 1 266 ? 153.272 119.404 130.084 1.00 31.55  ? 266 ARG A NE  1 
ATOM   1971  C CZ  . ARG A 1 266 ? 154.500 118.918 130.203 1.00 31.55  ? 266 ARG A CZ  1 
ATOM   1972  N NH1 . ARG A 1 266 ? 154.757 117.635 130.007 1.00 31.55  ? 266 ARG A NH1 1 
ATOM   1973  N NH2 . ARG A 1 266 ? 155.494 119.739 130.527 1.00 31.55  ? 266 ARG A NH2 1 
ATOM   1974  N N   . SER A 1 267 ? 151.988 121.295 124.793 1.00 25.83  ? 267 SER A N   1 
ATOM   1975  C CA  . SER A 1 267 ? 153.044 122.122 124.234 1.00 25.83  ? 267 SER A CA  1 
ATOM   1976  C C   . SER A 1 267 ? 152.527 123.528 123.941 1.00 25.83  ? 267 SER A C   1 
ATOM   1977  O O   . SER A 1 267 ? 151.321 123.770 123.864 1.00 25.83  ? 267 SER A O   1 
ATOM   1978  C CB  . SER A 1 267 ? 153.603 121.489 122.961 1.00 25.83  ? 267 SER A CB  1 
ATOM   1979  O OG  . SER A 1 267 ? 154.263 120.269 123.250 1.00 25.83  ? 267 SER A OG  1 
ATOM   1980  N N   . SER A 1 268 ? 153.463 124.460 123.776 1.00 23.40  ? 268 SER A N   1 
ATOM   1981  C CA  . SER A 1 268 ? 153.121 125.858 123.541 1.00 23.40  ? 268 SER A CA  1 
ATOM   1982  C C   . SER A 1 268 ? 154.321 126.561 122.917 1.00 23.40  ? 268 SER A C   1 
ATOM   1983  O O   . SER A 1 268 ? 155.337 125.939 122.596 1.00 23.40  ? 268 SER A O   1 
ATOM   1984  C CB  . SER A 1 268 ? 152.686 126.544 124.838 1.00 23.40  ? 268 SER A CB  1 
ATOM   1985  O OG  . SER A 1 268 ? 152.085 127.798 124.575 1.00 23.40  ? 268 SER A OG  1 
ATOM   1986  N N   . ILE A 1 269 ? 154.190 127.877 122.745 1.00 20.88  ? 269 ILE A N   1 
ATOM   1987  C CA  . ILE A 1 269 ? 155.231 128.713 122.162 1.00 20.88  ? 269 ILE A CA  1 
ATOM   1988  C C   . ILE A 1 269 ? 155.289 130.023 122.936 1.00 20.88  ? 269 ILE A C   1 
ATOM   1989  O O   . ILE A 1 269 ? 154.267 130.543 123.394 1.00 20.88  ? 269 ILE A O   1 
ATOM   1990  C CB  . ILE A 1 269 ? 154.987 128.959 120.652 1.00 20.88  ? 269 ILE A CB  1 
ATOM   1991  C CG1 . ILE A 1 269 ? 156.171 129.691 120.017 1.00 20.88  ? 269 ILE A CG1 1 
ATOM   1992  C CG2 . ILE A 1 269 ? 153.686 129.717 120.425 1.00 20.88  ? 269 ILE A CG2 1 
ATOM   1993  C CD1 . ILE A 1 269 ? 156.273 129.494 118.528 1.00 20.88  ? 269 ILE A CD1 1 
ATOM   1994  N N   . MET A 1 270 ? 156.502 130.549 123.099 1.00 22.14  ? 270 MET A N   1 
ATOM   1995  C CA  . MET A 1 270 ? 156.726 131.765 123.866 1.00 22.14  ? 270 MET A CA  1 
ATOM   1996  C C   . MET A 1 270 ? 157.733 132.645 123.139 1.00 22.14  ? 270 MET A C   1 
ATOM   1997  O O   . MET A 1 270 ? 158.657 132.150 122.490 1.00 22.14  ? 270 MET A O   1 
ATOM   1998  C CB  . MET A 1 270 ? 157.222 131.435 125.284 1.00 22.14  ? 270 MET A CB  1 
ATOM   1999  C CG  . MET A 1 270 ? 157.706 132.624 126.097 1.00 22.14  ? 270 MET A CG  1 
ATOM   2000  S SD  . MET A 1 270 ? 158.035 132.206 127.817 1.00 22.14  ? 270 MET A SD  1 
ATOM   2001  C CE  . MET A 1 270 ? 156.403 131.729 128.373 1.00 22.14  ? 270 MET A CE  1 
ATOM   2002  N N   . ARG A 1 271 ? 157.543 133.959 123.248 1.00 21.91  ? 271 ARG A N   1 
ATOM   2003  C CA  . ARG A 1 271 ? 158.489 134.940 122.730 1.00 21.91  ? 271 ARG A CA  1 
ATOM   2004  C C   . ARG A 1 271 ? 159.322 135.472 123.889 1.00 21.91  ? 271 ARG A C   1 
ATOM   2005  O O   . ARG A 1 271 ? 158.772 136.004 124.859 1.00 21.91  ? 271 ARG A O   1 
ATOM   2006  C CB  . ARG A 1 271 ? 157.769 136.093 122.030 1.00 21.91  ? 271 ARG A CB  1 
ATOM   2007  C CG  . ARG A 1 271 ? 156.949 135.710 120.815 1.00 21.91  ? 271 ARG A CG  1 
ATOM   2008  C CD  . ARG A 1 271 ? 156.372 136.956 120.163 1.00 21.91  ? 271 ARG A CD  1 
ATOM   2009  N NE  . ARG A 1 271 ? 155.470 136.652 119.058 1.00 21.91  ? 271 ARG A NE  1 
ATOM   2010  C CZ  . ARG A 1 271 ? 154.149 136.606 119.161 1.00 21.91  ? 271 ARG A CZ  1 
ATOM   2011  N NH1 . ARG A 1 271 ? 153.537 136.837 120.310 1.00 21.91  ? 271 ARG A NH1 1 
ATOM   2012  N NH2 . ARG A 1 271 ? 153.424 136.324 118.083 1.00 21.91  ? 271 ARG A NH2 1 
ATOM   2013  N N   . SER A 1 272 ? 160.642 135.337 123.785 1.00 25.83  ? 272 SER A N   1 
ATOM   2014  C CA  . SER A 1 272 ? 161.528 135.784 124.849 1.00 25.83  ? 272 SER A CA  1 
ATOM   2015  C C   . SER A 1 272 ? 162.939 135.926 124.299 1.00 25.83  ? 272 SER A C   1 
ATOM   2016  O O   . SER A 1 272 ? 163.297 135.296 123.302 1.00 25.83  ? 272 SER A O   1 
ATOM   2017  C CB  . SER A 1 272 ? 161.514 134.810 126.033 1.00 25.83  ? 272 SER A CB  1 
ATOM   2018  O OG  . SER A 1 272 ? 162.440 135.201 127.030 1.00 25.83  ? 272 SER A OG  1 
ATOM   2019  N N   . ASP A 1 273 ? 163.733 136.765 124.964 1.00 30.60  ? 273 ASP A N   1 
ATOM   2020  C CA  . ASP A 1 273 ? 165.142 136.941 124.636 1.00 30.60  ? 273 ASP A CA  1 
ATOM   2021  C C   . ASP A 1 273 ? 166.062 136.511 125.771 1.00 30.60  ? 273 ASP A C   1 
ATOM   2022  O O   . ASP A 1 273 ? 167.268 136.768 125.710 1.00 30.60  ? 273 ASP A O   1 
ATOM   2023  C CB  . ASP A 1 273 ? 165.424 138.396 124.258 1.00 30.60  ? 273 ASP A CB  1 
ATOM   2024  C CG  . ASP A 1 273 ? 165.239 138.661 122.778 1.00 30.60  ? 273 ASP A CG  1 
ATOM   2025  O OD1 . ASP A 1 273 ? 165.652 137.811 121.963 1.00 30.60  ? 273 ASP A OD1 1 
ATOM   2026  O OD2 . ASP A 1 273 ? 164.684 139.723 122.427 1.00 30.60  ? 273 ASP A OD2 1 
ATOM   2027  N N   . ALA A 1 274 ? 165.524 135.867 126.803 1.00 29.02  ? 274 ALA A N   1 
ATOM   2028  C CA  . ALA A 1 274 ? 166.353 135.402 127.903 1.00 29.02  ? 274 ALA A CA  1 
ATOM   2029  C C   . ALA A 1 274 ? 167.144 134.165 127.482 1.00 29.02  ? 274 ALA A C   1 
ATOM   2030  O O   . ALA A 1 274 ? 166.622 133.307 126.764 1.00 29.02  ? 274 ALA A O   1 
ATOM   2031  C CB  . ALA A 1 274 ? 165.493 135.083 129.123 1.00 29.02  ? 274 ALA A CB  1 
ATOM   2032  N N   . PRO A 1 275 ? 168.399 134.045 127.907 1.00 30.41  ? 275 PRO A N   1 
ATOM   2033  C CA  . PRO A 1 275 ? 169.182 132.851 127.572 1.00 30.41  ? 275 PRO A CA  1 
ATOM   2034  C C   . PRO A 1 275 ? 168.727 131.637 128.368 1.00 30.41  ? 275 PRO A C   1 
ATOM   2035  O O   . PRO A 1 275 ? 168.042 131.742 129.387 1.00 30.41  ? 275 PRO A O   1 
ATOM   2036  C CB  . PRO A 1 275 ? 170.615 133.249 127.937 1.00 30.41  ? 275 PRO A CB  1 
ATOM   2037  C CG  . PRO A 1 275 ? 170.461 134.321 128.953 1.00 30.41  ? 275 PRO A CG  1 
ATOM   2038  C CD  . PRO A 1 275 ? 169.204 135.060 128.607 1.00 30.41  ? 275 PRO A CD  1 
ATOM   2039  N N   . ILE A 1 276 ? 169.128 130.465 127.882 1.00 34.04  ? 276 ILE A N   1 
ATOM   2040  C CA  . ILE A 1 276 ? 168.754 129.183 128.470 1.00 34.04  ? 276 ILE A CA  1 
ATOM   2041  C C   . ILE A 1 276 ? 169.977 128.593 129.157 1.00 34.04  ? 276 ILE A C   1 
ATOM   2042  O O   . ILE A 1 276 ? 171.056 128.515 128.557 1.00 34.04  ? 276 ILE A O   1 
ATOM   2043  C CB  . ILE A 1 276 ? 168.196 128.219 127.409 1.00 34.04  ? 276 ILE A CB  1 
ATOM   2044  C CG1 . ILE A 1 276 ? 167.079 128.896 126.613 1.00 34.04  ? 276 ILE A CG1 1 
ATOM   2045  C CG2 . ILE A 1 276 ? 167.690 126.944 128.060 1.00 34.04  ? 276 ILE A CG2 1 
ATOM   2046  C CD1 . ILE A 1 276 ? 166.489 128.030 125.530 1.00 34.04  ? 276 ILE A CD1 1 
ATOM   2047  N N   . GLU A 1 277 ? 169.809 128.176 130.410 1.00 38.67  ? 277 GLU A N   1 
ATOM   2048  C CA  . GLU A 1 277 ? 170.909 127.697 131.234 1.00 38.67  ? 277 GLU A CA  1 
ATOM   2049  C C   . GLU A 1 277 ? 170.569 126.326 131.802 1.00 38.67  ? 277 GLU A C   1 
ATOM   2050  O O   . GLU A 1 277 ? 169.429 125.862 131.733 1.00 38.67  ? 277 GLU A O   1 
ATOM   2051  C CB  . GLU A 1 277 ? 171.220 128.680 132.370 1.00 38.67  ? 277 GLU A CB  1 
ATOM   2052  C CG  . GLU A 1 277 ? 171.753 130.024 131.901 1.00 38.67  ? 277 GLU A CG  1 
ATOM   2053  C CD  . GLU A 1 277 ? 173.119 129.922 131.255 1.00 38.67  ? 277 GLU A CD  1 
ATOM   2054  O OE1 . GLU A 1 277 ? 173.907 129.041 131.659 1.00 38.67  ? 277 GLU A OE1 1 
ATOM   2055  O OE2 . GLU A 1 277 ? 173.404 130.724 130.340 1.00 38.67  ? 277 GLU A OE2 1 
ATOM   2056  N N   . THR A 1 278 ? 171.580 125.677 132.378 1.00 40.57  ? 278 THR A N   1 
ATOM   2057  C CA  . THR A 1 278 ? 171.421 124.355 132.982 1.00 40.57  ? 278 THR A CA  1 
ATOM   2058  C C   . THR A 1 278 ? 170.988 124.542 134.430 1.00 40.57  ? 278 THR A C   1 
ATOM   2059  O O   . THR A 1 278 ? 171.796 124.886 135.295 1.00 40.57  ? 278 THR A O   1 
ATOM   2060  C CB  . THR A 1 278 ? 172.715 123.555 132.884 1.00 40.57  ? 278 THR A CB  1 
ATOM   2061  O OG1 . THR A 1 278 ? 173.049 123.351 131.505 1.00 40.57  ? 278 THR A OG1 1 
ATOM   2062  C CG2 . THR A 1 278 ? 172.556 122.203 133.562 1.00 40.57  ? 278 THR A CG2 1 
ATOM   2063  N N   . CYS A 1 279 ? 169.708 124.301 134.693 1.00 39.19  ? 279 CYS A N   1 
ATOM   2064  C CA  . CYS A 1 279 ? 169.095 124.517 135.998 1.00 39.19  ? 279 CYS A CA  1 
ATOM   2065  C C   . CYS A 1 279 ? 167.706 123.897 135.976 1.00 39.19  ? 279 CYS A C   1 
ATOM   2066  O O   . CYS A 1 279 ? 167.237 123.419 134.939 1.00 39.19  ? 279 CYS A O   1 
ATOM   2067  C CB  . CYS A 1 279 ? 169.066 126.009 136.358 1.00 39.19  ? 279 CYS A CB  1 
ATOM   2068  S SG  . CYS A 1 279 ? 168.058 127.080 135.288 1.00 39.19  ? 279 CYS A SG  1 
ATOM   2069  N N   . ILE A 1 280 ? 167.057 123.892 137.139 1.00 36.24  ? 280 ILE A N   1 
ATOM   2070  C CA  . ILE A 1 280 ? 165.760 123.249 137.318 1.00 36.24  ? 280 ILE A CA  1 
ATOM   2071  C C   . ILE A 1 280 ? 164.766 124.276 137.838 1.00 36.24  ? 280 ILE A C   1 
ATOM   2072  O O   . ILE A 1 280 ? 165.010 124.920 138.866 1.00 36.24  ? 280 ILE A O   1 
ATOM   2073  C CB  . ILE A 1 280 ? 165.851 122.047 138.277 1.00 36.24  ? 280 ILE A CB  1 
ATOM   2074  C CG1 . ILE A 1 280 ? 166.724 120.948 137.672 1.00 36.24  ? 280 ILE A CG1 1 
ATOM   2075  C CG2 . ILE A 1 280 ? 164.466 121.507 138.586 1.00 36.24  ? 280 ILE A CG2 1 
ATOM   2076  C CD1 . ILE A 1 280 ? 166.883 119.737 138.561 1.00 36.24  ? 280 ILE A CD1 1 
ATOM   2077  N N   . SER A 1 281 ? 163.646 124.423 137.132 1.00 32.97  ? 281 SER A N   1 
ATOM   2078  C CA  . SER A 1 281 ? 162.561 125.291 137.564 1.00 32.97  ? 281 SER A CA  1 
ATOM   2079  C C   . SER A 1 281 ? 161.293 124.880 136.831 1.00 32.97  ? 281 SER A C   1 
ATOM   2080  O O   . SER A 1 281 ? 161.337 124.558 135.642 1.00 32.97  ? 281 SER A O   1 
ATOM   2081  C CB  . SER A 1 281 ? 162.873 126.767 137.298 1.00 32.97  ? 281 SER A CB  1 
ATOM   2082  O OG  . SER A 1 281 ? 162.009 127.611 138.039 1.00 32.97  ? 281 SER A OG  1 
ATOM   2083  N N   . GLU A 1 282 ? 160.171 124.895 137.546 1.00 33.39  ? 282 GLU A N   1 
ATOM   2084  C CA  . GLU A 1 282 ? 158.900 124.453 136.990 1.00 33.39  ? 282 GLU A CA  1 
ATOM   2085  C C   . GLU A 1 282 ? 158.096 125.574 136.345 1.00 33.39  ? 282 GLU A C   1 
ATOM   2086  O O   . GLU A 1 282 ? 157.096 125.289 135.680 1.00 33.39  ? 282 GLU A O   1 
ATOM   2087  C CB  . GLU A 1 282 ? 158.051 123.790 138.078 1.00 33.39  ? 282 GLU A CB  1 
ATOM   2088  C CG  . GLU A 1 282 ? 158.618 122.483 138.595 1.00 33.39  ? 282 GLU A CG  1 
ATOM   2089  C CD  . GLU A 1 282 ? 157.761 121.869 139.682 1.00 33.39  ? 282 GLU A CD  1 
ATOM   2090  O OE1 . GLU A 1 282 ? 156.793 122.525 140.120 1.00 33.39  ? 282 GLU A OE1 1 
ATOM   2091  O OE2 . GLU A 1 282 ? 158.056 120.731 140.102 1.00 33.39  ? 282 GLU A OE2 1 
ATOM   2092  N N   . CYS A 1 283 ? 158.498 126.830 136.519 1.00 30.07  ? 283 CYS A N   1 
ATOM   2093  C CA  . CYS A 1 283 ? 157.767 127.970 135.985 1.00 30.07  ? 283 CYS A CA  1 
ATOM   2094  C C   . CYS A 1 283 ? 158.665 128.746 135.034 1.00 30.07  ? 283 CYS A C   1 
ATOM   2095  O O   . CYS A 1 283 ? 159.823 129.027 135.358 1.00 30.07  ? 283 CYS A O   1 
ATOM   2096  C CB  . CYS A 1 283 ? 157.271 128.880 137.110 1.00 30.07  ? 283 CYS A CB  1 
ATOM   2097  S SG  . CYS A 1 283 ? 156.304 130.292 136.547 1.00 30.07  ? 283 CYS A SG  1 
ATOM   2098  N N   . ILE A 1 284 ? 158.130 129.090 133.865 1.00 26.68  ? 284 ILE A N   1 
ATOM   2099  C CA  . ILE A 1 284 ? 158.855 129.838 132.845 1.00 26.68  ? 284 ILE A CA  1 
ATOM   2100  C C   . ILE A 1 284 ? 158.051 131.082 132.497 1.00 26.68  ? 284 ILE A C   1 
ATOM   2101  O O   . ILE A 1 284 ? 156.835 131.004 132.293 1.00 26.68  ? 284 ILE A O   1 
ATOM   2102  C CB  . ILE A 1 284 ? 159.115 128.988 131.588 1.00 26.68  ? 284 ILE A CB  1 
ATOM   2103  C CG1 . ILE A 1 284 ? 159.848 127.697 131.951 1.00 26.68  ? 284 ILE A CG1 1 
ATOM   2104  C CG2 . ILE A 1 284 ? 159.917 129.776 130.568 1.00 26.68  ? 284 ILE A CG2 1 
ATOM   2105  C CD1 . ILE A 1 284 ? 159.746 126.625 130.896 1.00 26.68  ? 284 ILE A CD1 1 
ATOM   2106  N N   . THR A 1 285 ? 158.729 132.219 132.439 1.00 25.98  ? 285 THR A N   1 
ATOM   2107  C CA  . THR A 1 285 ? 158.176 133.497 132.023 1.00 25.98  ? 285 THR A CA  1 
ATOM   2108  C C   . THR A 1 285 ? 159.093 134.094 130.969 1.00 25.98  ? 285 THR A C   1 
ATOM   2109  O O   . THR A 1 285 ? 160.253 133.687 130.846 1.00 25.98  ? 285 THR A O   1 
ATOM   2110  C CB  . THR A 1 285 ? 158.035 134.469 133.206 1.00 25.98  ? 285 THR A CB  1 
ATOM   2111  O OG1 . THR A 1 285 ? 159.331 134.798 133.718 1.00 25.98  ? 285 THR A OG1 1 
ATOM   2112  C CG2 . THR A 1 285 ? 157.193 133.860 134.315 1.00 25.98  ? 285 THR A CG2 1 
ATOM   2113  N N   . PRO A 1 286 ? 158.599 135.045 130.169 1.00 24.99  ? 286 PRO A N   1 
ATOM   2114  C CA  . PRO A 1 286 ? 159.490 135.710 129.205 1.00 24.99  ? 286 PRO A CA  1 
ATOM   2115  C C   . PRO A 1 286 ? 160.671 136.407 129.856 1.00 24.99  ? 286 PRO A C   1 
ATOM   2116  O O   . PRO A 1 286 ? 161.710 136.579 129.207 1.00 24.99  ? 286 PRO A O   1 
ATOM   2117  C CB  . PRO A 1 286 ? 158.559 136.707 128.503 1.00 24.99  ? 286 PRO A CB  1 
ATOM   2118  C CG  . PRO A 1 286 ? 157.212 136.108 128.631 1.00 24.99  ? 286 PRO A CG  1 
ATOM   2119  C CD  . PRO A 1 286 ? 157.191 135.428 129.966 1.00 24.99  ? 286 PRO A CD  1 
ATOM   2120  N N   . ASN A 1 287 ? 160.543 136.821 131.118 1.00 28.36  ? 287 ASN A N   1 
ATOM   2121  C CA  . ASN A 1 287 ? 161.671 137.386 131.847 1.00 28.36  ? 287 ASN A CA  1 
ATOM   2122  C C   . ASN A 1 287 ? 162.659 136.325 132.310 1.00 28.36  ? 287 ASN A C   1 
ATOM   2123  O O   . ASN A 1 287 ? 163.813 136.656 132.600 1.00 28.36  ? 287 ASN A O   1 
ATOM   2124  C CB  . ASN A 1 287 ? 161.177 138.175 133.061 1.00 28.36  ? 287 ASN A CB  1 
ATOM   2125  C CG  . ASN A 1 287 ? 160.088 139.167 132.712 1.00 28.36  ? 287 ASN A CG  1 
ATOM   2126  O OD1 . ASN A 1 287 ? 159.060 138.803 132.145 1.00 28.36  ? 287 ASN A OD1 1 
ATOM   2127  N ND2 . ASN A 1 287 ? 160.306 140.430 133.058 1.00 28.36  ? 287 ASN A ND2 1 
ATOM   2128  N N   . GLY A 1 288 ? 162.237 135.068 132.383 1.00 27.29  ? 288 GLY A N   1 
ATOM   2129  C CA  . GLY A 1 288 ? 163.043 133.981 132.890 1.00 27.29  ? 288 GLY A CA  1 
ATOM   2130  C C   . GLY A 1 288 ? 162.250 133.105 133.834 1.00 27.29  ? 288 GLY A C   1 
ATOM   2131  O O   . GLY A 1 288 ? 161.057 133.301 134.061 1.00 27.29  ? 288 GLY A O   1 
ATOM   2132  N N   . SER A 1 289 ? 162.940 132.116 134.394 1.00 29.69  ? 289 SER A N   1 
ATOM   2133  C CA  . SER A 1 289 ? 162.317 131.202 135.340 1.00 29.69  ? 289 SER A CA  1 
ATOM   2134  C C   . SER A 1 289 ? 162.192 131.853 136.712 1.00 29.69  ? 289 SER A C   1 
ATOM   2135  O O   . SER A 1 289 ? 163.078 132.594 137.146 1.00 29.69  ? 289 SER A O   1 
ATOM   2136  C CB  . SER A 1 289 ? 163.127 129.911 135.447 1.00 29.69  ? 289 SER A CB  1 
ATOM   2137  O OG  . SER A 1 289 ? 162.994 129.125 134.276 1.00 29.69  ? 289 SER A OG  1 
ATOM   2138  N N   . ILE A 1 290 ? 161.082 131.576 137.391 1.00 28.99  ? 290 ILE A N   1 
ATOM   2139  C CA  . ILE A 1 290 ? 160.847 132.098 138.736 1.00 28.99  ? 290 ILE A CA  1 
ATOM   2140  C C   . ILE A 1 290 ? 160.453 130.950 139.659 1.00 28.99  ? 290 ILE A C   1 
ATOM   2141  O O   . ILE A 1 290 ? 159.850 129.967 139.203 1.00 28.99  ? 290 ILE A O   1 
ATOM   2142  C CB  . ILE A 1 290 ? 159.770 133.196 138.735 1.00 28.99  ? 290 ILE A CB  1 
ATOM   2143  C CG1 . ILE A 1 290 ? 158.434 132.645 138.236 1.00 28.99  ? 290 ILE A CG1 1 
ATOM   2144  C CG2 . ILE A 1 290 ? 160.205 134.379 137.891 1.00 28.99  ? 290 ILE A CG2 1 
ATOM   2145  C CD1 . ILE A 1 290 ? 157.255 133.536 138.546 1.00 28.99  ? 290 ILE A CD1 1 
ATOM   2146  N N   . PRO A 1 291 ? 160.781 131.017 140.948 1.00 29.89  ? 291 PRO A N   1 
ATOM   2147  C CA  . PRO A 1 291 ? 160.329 129.977 141.877 1.00 29.89  ? 291 PRO A CA  1 
ATOM   2148  C C   . PRO A 1 291 ? 158.835 130.073 142.138 1.00 29.89  ? 291 PRO A C   1 
ATOM   2149  O O   . PRO A 1 291 ? 158.230 131.144 142.046 1.00 29.89  ? 291 PRO A O   1 
ATOM   2150  C CB  . PRO A 1 291 ? 161.137 130.259 143.148 1.00 29.89  ? 291 PRO A CB  1 
ATOM   2151  C CG  . PRO A 1 291 ? 161.501 131.695 143.054 1.00 29.89  ? 291 PRO A CG  1 
ATOM   2152  C CD  . PRO A 1 291 ? 161.664 132.000 141.598 1.00 29.89  ? 291 PRO A CD  1 
ATOM   2153  N N   . ASN A 1 292 ? 158.238 128.929 142.474 1.00 31.17  ? 292 ASN A N   1 
ATOM   2154  C CA  . ASN A 1 292 ? 156.801 128.832 142.697 1.00 31.17  ? 292 ASN A CA  1 
ATOM   2155  C C   . ASN A 1 292 ? 156.473 128.481 144.145 1.00 31.17  ? 292 ASN A C   1 
ATOM   2156  O O   . ASN A 1 292 ? 155.514 127.756 144.414 1.00 31.17  ? 292 ASN A O   1 
ATOM   2157  C CB  . ASN A 1 292 ? 156.173 127.815 141.743 1.00 31.17  ? 292 ASN A CB  1 
ATOM   2158  C CG  . ASN A 1 292 ? 156.808 126.442 141.849 1.00 31.17  ? 292 ASN A CG  1 
ATOM   2159  O OD1 . ASN A 1 292 ? 157.772 126.244 142.586 1.00 31.17  ? 292 ASN A OD1 1 
ATOM   2160  N ND2 . ASN A 1 292 ? 156.267 125.485 141.108 1.00 31.17  ? 292 ASN A ND2 1 
ATOM   2161  N N   . ASP A 1 293 ? 157.262 128.993 145.089 1.00 33.03  ? 293 ASP A N   1 
ATOM   2162  C CA  . ASP A 1 293 ? 157.006 128.759 146.504 1.00 33.03  ? 293 ASP A CA  1 
ATOM   2163  C C   . ASP A 1 293 ? 156.030 129.762 147.105 1.00 33.03  ? 293 ASP A C   1 
ATOM   2164  O O   . ASP A 1 293 ? 155.658 129.614 148.273 1.00 33.03  ? 293 ASP A O   1 
ATOM   2165  C CB  . ASP A 1 293 ? 158.321 128.788 147.286 1.00 33.03  ? 293 ASP A CB  1 
ATOM   2166  C CG  . ASP A 1 293 ? 159.164 130.005 146.965 1.00 33.03  ? 293 ASP A CG  1 
ATOM   2167  O OD1 . ASP A 1 293 ? 158.765 130.792 146.082 1.00 33.03  ? 293 ASP A OD1 1 
ATOM   2168  O OD2 . ASP A 1 293 ? 160.228 130.175 147.594 1.00 33.03  ? 293 ASP A OD2 1 
ATOM   2169  N N   . LYS A 1 294 ? 155.609 130.769 146.342 1.00 27.74  ? 294 LYS A N   1 
ATOM   2170  C CA  . LYS A 1 294 ? 154.647 131.765 146.777 1.00 27.74  ? 294 LYS A CA  1 
ATOM   2171  C C   . LYS A 1 294 ? 153.356 131.643 145.971 1.00 27.74  ? 294 LYS A C   1 
ATOM   2172  O O   . LYS A 1 294 ? 153.376 131.184 144.826 1.00 27.74  ? 294 LYS A O   1 
ATOM   2173  C CB  . LYS A 1 294 ? 155.217 133.180 146.622 1.00 27.74  ? 294 LYS A CB  1 
ATOM   2174  C CG  . LYS A 1 294 ? 156.263 133.534 147.663 1.00 27.74  ? 294 LYS A CG  1 
ATOM   2175  C CD  . LYS A 1 294 ? 156.984 134.820 147.313 1.00 27.74  ? 294 LYS A CD  1 
ATOM   2176  C CE  . LYS A 1 294 ? 158.378 134.843 147.911 1.00 27.74  ? 294 LYS A CE  1 
ATOM   2177  N NZ  . LYS A 1 294 ? 158.939 136.219 147.958 1.00 27.74  ? 294 LYS A NZ  1 
ATOM   2178  N N   . PRO A 1 295 ? 152.212 132.034 146.541 1.00 24.89  ? 295 PRO A N   1 
ATOM   2179  C CA  . PRO A 1 295 ? 150.941 131.880 145.819 1.00 24.89  ? 295 PRO A CA  1 
ATOM   2180  C C   . PRO A 1 295 ? 150.689 132.932 144.750 1.00 24.89  ? 295 PRO A C   1 
ATOM   2181  O O   . PRO A 1 295 ? 149.802 132.725 143.910 1.00 24.89  ? 295 PRO A O   1 
ATOM   2182  C CB  . PRO A 1 295 ? 149.896 131.978 146.938 1.00 24.89  ? 295 PRO A CB  1 
ATOM   2183  C CG  . PRO A 1 295 ? 150.540 132.825 147.969 1.00 24.89  ? 295 PRO A CG  1 
ATOM   2184  C CD  . PRO A 1 295 ? 152.011 132.528 147.915 1.00 24.89  ? 295 PRO A CD  1 
ATOM   2185  N N   . PHE A 1 296 ? 151.427 134.039 144.746 1.00 23.81  ? 296 PHE A N   1 
ATOM   2186  C CA  . PHE A 1 296 ? 151.222 135.115 143.787 1.00 23.81  ? 296 PHE A CA  1 
ATOM   2187  C C   . PHE A 1 296 ? 152.564 135.564 143.225 1.00 23.81  ? 296 PHE A C   1 
ATOM   2188  O O   . PHE A 1 296 ? 153.612 135.380 143.847 1.00 23.81  ? 296 PHE A O   1 
ATOM   2189  C CB  . PHE A 1 296 ? 150.494 136.306 144.425 1.00 23.81  ? 296 PHE A CB  1 
ATOM   2190  C CG  . PHE A 1 296 ? 149.236 135.929 145.154 1.00 23.81  ? 296 PHE A CG  1 
ATOM   2191  C CD1 . PHE A 1 296 ? 148.149 135.416 144.466 1.00 23.81  ? 296 PHE A CD1 1 
ATOM   2192  C CD2 . PHE A 1 296 ? 149.142 136.083 146.526 1.00 23.81  ? 296 PHE A CD2 1 
ATOM   2193  C CE1 . PHE A 1 296 ? 146.992 135.065 145.134 1.00 23.81  ? 296 PHE A CE1 1 
ATOM   2194  C CE2 . PHE A 1 296 ? 147.988 135.733 147.199 1.00 23.81  ? 296 PHE A CE2 1 
ATOM   2195  C CZ  . PHE A 1 296 ? 146.913 135.223 146.502 1.00 23.81  ? 296 PHE A CZ  1 
ATOM   2196  N N   . GLN A 1 297 ? 152.522 136.155 142.031 1.00 23.35  ? 297 GLN A N   1 
ATOM   2197  C CA  . GLN A 1 297 ? 153.722 136.667 141.386 1.00 23.35  ? 297 GLN A CA  1 
ATOM   2198  C C   . GLN A 1 297 ? 153.384 137.935 140.615 1.00 23.35  ? 297 GLN A C   1 
ATOM   2199  O O   . GLN A 1 297 ? 152.232 138.181 140.251 1.00 23.35  ? 297 GLN A O   1 
ATOM   2200  C CB  . GLN A 1 297 ? 154.372 135.607 140.477 1.00 23.35  ? 297 GLN A CB  1 
ATOM   2201  C CG  . GLN A 1 297 ? 153.541 135.119 139.292 1.00 23.35  ? 297 GLN A CG  1 
ATOM   2202  C CD  . GLN A 1 297 ? 153.673 135.992 138.060 1.00 23.35  ? 297 GLN A CD  1 
ATOM   2203  O OE1 . GLN A 1 297 ? 154.707 136.616 137.836 1.00 23.35  ? 297 GLN A OE1 1 
ATOM   2204  N NE2 . GLN A 1 297 ? 152.634 136.015 137.240 1.00 23.35  ? 297 GLN A NE2 1 
ATOM   2205  N N   . ASN A 1 298 ? 154.418 138.747 140.376 1.00 24.19  ? 298 ASN A N   1 
ATOM   2206  C CA  . ASN A 1 298 ? 154.270 140.065 139.768 1.00 24.19  ? 298 ASN A CA  1 
ATOM   2207  C C   . ASN A 1 298 ? 155.244 140.272 138.611 1.00 24.19  ? 298 ASN A C   1 
ATOM   2208  O O   . ASN A 1 298 ? 155.491 141.413 138.211 1.00 24.19  ? 298 ASN A O   1 
ATOM   2209  C CB  . ASN A 1 298 ? 154.463 141.157 140.827 1.00 24.19  ? 298 ASN A CB  1 
ATOM   2210  C CG  . ASN A 1 298 ? 153.925 142.503 140.390 1.00 24.19  ? 298 ASN A CG  1 
ATOM   2211  O OD1 . ASN A 1 298 ? 152.911 142.587 139.701 1.00 24.19  ? 298 ASN A OD1 1 
ATOM   2212  N ND2 . ASN A 1 298 ? 154.608 143.568 140.790 1.00 24.19  ? 298 ASN A ND2 1 
ATOM   2213  N N   . VAL A 1 299 ? 155.798 139.197 138.061 1.00 24.38  ? 299 VAL A N   1 
ATOM   2214  C CA  . VAL A 1 299 ? 156.834 139.313 137.039 1.00 24.38  ? 299 VAL A CA  1 
ATOM   2215  C C   . VAL A 1 299 ? 156.232 139.475 135.649 1.00 24.38  ? 299 VAL A C   1 
ATOM   2216  O O   . VAL A 1 299 ? 156.534 140.436 134.939 1.00 24.38  ? 299 VAL A O   1 
ATOM   2217  C CB  . VAL A 1 299 ? 157.775 138.092 137.109 1.00 24.38  ? 299 VAL A CB  1 
ATOM   2218  C CG1 . VAL A 1 299 ? 158.889 138.220 136.086 1.00 24.38  ? 299 VAL A CG1 1 
ATOM   2219  C CG2 . VAL A 1 299 ? 158.343 137.945 138.508 1.00 24.38  ? 299 VAL A CG2 1 
ATOM   2220  N N   . ASN A 1 300 ? 155.372 138.546 135.240 1.00 23.68  ? 300 ASN A N   1 
ATOM   2221  C CA  . ASN A 1 300 ? 154.792 138.579 133.906 1.00 23.68  ? 300 ASN A CA  1 
ATOM   2222  C C   . ASN A 1 300 ? 153.466 137.836 133.929 1.00 23.68  ? 300 ASN A C   1 
ATOM   2223  O O   . ASN A 1 300 ? 153.315 136.856 134.661 1.00 23.68  ? 300 ASN A O   1 
ATOM   2224  C CB  . ASN A 1 300 ? 155.737 137.948 132.876 1.00 23.68  ? 300 ASN A CB  1 
ATOM   2225  C CG  . ASN A 1 300 ? 155.632 138.594 131.510 1.00 23.68  ? 300 ASN A CG  1 
ATOM   2226  O OD1 . ASN A 1 300 ? 154.551 138.682 130.932 1.00 23.68  ? 300 ASN A OD1 1 
ATOM   2227  N ND2 . ASN A 1 300 ? 156.760 139.051 130.986 1.00 23.68  ? 300 ASN A ND2 1 
ATOM   2228  N N   . LYS A 1 301 ? 152.513 138.306 133.127 1.00 24.05  ? 301 LYS A N   1 
ATOM   2229  C CA  . LYS A 1 301 ? 151.237 137.617 132.993 1.00 24.05  ? 301 LYS A CA  1 
ATOM   2230  C C   . LYS A 1 301 ? 151.278 136.498 131.960 1.00 24.05  ? 301 LYS A C   1 
ATOM   2231  O O   . LYS A 1 301 ? 150.278 135.793 131.795 1.00 24.05  ? 301 LYS A O   1 
ATOM   2232  C CB  . LYS A 1 301 ? 150.129 138.614 132.645 1.00 24.05  ? 301 LYS A CB  1 
ATOM   2233  C CG  . LYS A 1 301 ? 150.294 139.307 131.311 1.00 24.05  ? 301 LYS A CG  1 
ATOM   2234  C CD  . LYS A 1 301 ? 149.305 140.451 131.171 1.00 24.05  ? 301 LYS A CD  1 
ATOM   2235  C CE  . LYS A 1 301 ? 149.264 140.977 129.747 1.00 24.05  ? 301 LYS A CE  1 
ATOM   2236  N NZ  . LYS A 1 301 ? 150.036 142.239 129.592 1.00 24.05  ? 301 LYS A NZ  1 
ATOM   2237  N N   . ILE A 1 302 ? 152.400 136.320 131.270 1.00 24.35  ? 302 ILE A N   1 
ATOM   2238  C CA  . ILE A 1 302 ? 152.616 135.192 130.372 1.00 24.35  ? 302 ILE A CA  1 
ATOM   2239  C C   . ILE A 1 302 ? 153.465 134.170 131.115 1.00 24.35  ? 302 ILE A C   1 
ATOM   2240  O O   . ILE A 1 302 ? 154.587 134.474 131.535 1.00 24.35  ? 302 ILE A O   1 
ATOM   2241  C CB  . ILE A 1 302 ? 153.293 135.634 129.066 1.00 24.35  ? 302 ILE A CB  1 
ATOM   2242  C CG1 . ILE A 1 302 ? 152.383 136.586 128.288 1.00 24.35  ? 302 ILE A CG1 1 
ATOM   2243  C CG2 . ILE A 1 302 ? 153.662 134.428 128.219 1.00 24.35  ? 302 ILE A CG2 1 
ATOM   2244  C CD1 . ILE A 1 302 ? 153.126 137.554 127.402 1.00 24.35  ? 302 ILE A CD1 1 
ATOM   2245  N N   . THR A 1 303 ? 152.934 132.961 131.286 1.00 27.67  ? 303 THR A N   1 
ATOM   2246  C CA  . THR A 1 303 ? 153.596 131.928 132.070 1.00 27.67  ? 303 THR A CA  1 
ATOM   2247  C C   . THR A 1 303 ? 153.401 130.572 131.406 1.00 27.67  ? 303 THR A C   1 
ATOM   2248  O O   . THR A 1 303 ? 152.497 130.379 130.590 1.00 27.67  ? 303 THR A O   1 
ATOM   2249  C CB  . THR A 1 303 ? 153.068 131.873 133.515 1.00 27.67  ? 303 THR A CB  1 
ATOM   2250  O OG1 . THR A 1 303 ? 151.646 131.696 133.502 1.00 27.67  ? 303 THR A OG1 1 
ATOM   2251  C CG2 . THR A 1 303 ? 153.417 133.142 134.283 1.00 27.67  ? 303 THR A CG2 1 
ATOM   2252  N N   . TYR A 1 304 ? 154.269 129.630 131.770 1.00 26.01  ? 304 TYR A N   1 
ATOM   2253  C CA  . TYR A 1 304 ? 154.166 128.253 131.303 1.00 26.01  ? 304 TYR A CA  1 
ATOM   2254  C C   . TYR A 1 304 ? 154.604 127.318 132.418 1.00 26.01  ? 304 TYR A C   1 
ATOM   2255  O O   . TYR A 1 304 ? 155.732 127.422 132.909 1.00 26.01  ? 304 TYR A O   1 
ATOM   2256  C CB  . TYR A 1 304 ? 155.020 128.021 130.051 1.00 26.01  ? 304 TYR A CB  1 
ATOM   2257  C CG  . TYR A 1 304 ? 154.953 126.602 129.532 1.00 26.01  ? 304 TYR A CG  1 
ATOM   2258  C CD1 . TYR A 1 304 ? 153.875 126.170 128.774 1.00 26.01  ? 304 TYR A CD1 1 
ATOM   2259  C CD2 . TYR A 1 304 ? 155.965 125.692 129.806 1.00 26.01  ? 304 TYR A CD2 1 
ATOM   2260  C CE1 . TYR A 1 304 ? 153.807 124.876 128.303 1.00 26.01  ? 304 TYR A CE1 1 
ATOM   2261  C CE2 . TYR A 1 304 ? 155.905 124.395 129.338 1.00 26.01  ? 304 TYR A CE2 1 
ATOM   2262  C CZ  . TYR A 1 304 ? 154.823 123.993 128.588 1.00 26.01  ? 304 TYR A CZ  1 
ATOM   2263  O OH  . TYR A 1 304 ? 154.756 122.703 128.118 1.00 26.01  ? 304 TYR A OH  1 
ATOM   2264  N N   . GLY A 1 305 ? 153.716 126.408 132.811 1.00 30.09  ? 305 GLY A N   1 
ATOM   2265  C CA  . GLY A 1 305 ? 154.037 125.432 133.835 1.00 30.09  ? 305 GLY A CA  1 
ATOM   2266  C C   . GLY A 1 305 ? 153.246 125.617 135.112 1.00 30.09  ? 305 GLY A C   1 
ATOM   2267  O O   . GLY A 1 305 ? 152.115 126.108 135.083 1.00 30.09  ? 305 GLY A O   1 
ATOM   2268  N N   . ALA A 1 306 ? 153.829 125.221 136.242 1.00 31.93  ? 306 ALA A N   1 
ATOM   2269  C CA  . ALA A 1 306 ? 153.213 125.416 137.553 1.00 31.93  ? 306 ALA A CA  1 
ATOM   2270  C C   . ALA A 1 306 ? 153.704 126.750 138.099 1.00 31.93  ? 306 ALA A C   1 
ATOM   2271  O O   . ALA A 1 306 ? 154.821 126.852 138.611 1.00 31.93  ? 306 ALA A O   1 
ATOM   2272  C CB  . ALA A 1 306 ? 153.554 124.264 138.490 1.00 31.93  ? 306 ALA A CB  1 
ATOM   2273  N N   . CYS A 1 307 ? 152.865 127.775 137.998 1.00 31.63  ? 307 CYS A N   1 
ATOM   2274  C CA  . CYS A 1 307 ? 153.272 129.137 138.295 1.00 31.63  ? 307 CYS A CA  1 
ATOM   2275  C C   . CYS A 1 307 ? 152.307 129.788 139.273 1.00 31.63  ? 307 CYS A C   1 
ATOM   2276  O O   . CYS A 1 307 ? 151.126 129.430 139.320 1.00 31.63  ? 307 CYS A O   1 
ATOM   2277  C CB  . CYS A 1 307 ? 153.335 129.979 137.012 1.00 31.63  ? 307 CYS A CB  1 
ATOM   2278  S SG  . CYS A 1 307 ? 154.597 129.460 135.835 1.00 31.63  ? 307 CYS A SG  1 
ATOM   2279  N N   . PRO A 1 308 ? 152.784 130.743 140.066 1.00 26.40  ? 308 PRO A N   1 
ATOM   2280  C CA  . PRO A 1 308 ? 151.877 131.520 140.915 1.00 26.40  ? 308 PRO A CA  1 
ATOM   2281  C C   . PRO A 1 308 ? 150.986 132.428 140.081 1.00 26.40  ? 308 PRO A C   1 
ATOM   2282  O O   . PRO A 1 308 ? 151.296 132.778 138.940 1.00 26.40  ? 308 PRO A O   1 
ATOM   2283  C CB  . PRO A 1 308 ? 152.821 132.336 141.805 1.00 26.40  ? 308 PRO A CB  1 
ATOM   2284  C CG  . PRO A 1 308 ? 154.168 131.710 141.649 1.00 26.40  ? 308 PRO A CG  1 
ATOM   2285  C CD  . PRO A 1 308 ? 154.195 131.092 140.295 1.00 26.40  ? 308 PRO A CD  1 
ATOM   2286  N N   . LYS A 1 309 ? 149.856 132.805 140.669 1.00 23.68  ? 309 LYS A N   1 
ATOM   2287  C CA  . LYS A 1 309 ? 148.905 133.662 139.978 1.00 23.68  ? 309 LYS A CA  1 
ATOM   2288  C C   . LYS A 1 309 ? 149.427 135.092 139.890 1.00 23.68  ? 309 LYS A C   1 
ATOM   2289  O O   . LYS A 1 309 ? 150.121 135.582 140.783 1.00 23.68  ? 309 LYS A O   1 
ATOM   2290  C CB  . LYS A 1 309 ? 147.554 133.637 140.687 1.00 23.68  ? 309 LYS A CB  1 
ATOM   2291  C CG  . LYS A 1 309 ? 146.981 132.244 140.840 1.00 23.68  ? 309 LYS A CG  1 
ATOM   2292  C CD  . LYS A 1 309 ? 145.545 132.279 141.310 1.00 23.68  ? 309 LYS A CD  1 
ATOM   2293  C CE  . LYS A 1 309 ? 145.051 130.883 141.634 1.00 23.68  ? 309 LYS A CE  1 
ATOM   2294  N NZ  . LYS A 1 309 ? 145.598 130.394 142.927 1.00 23.68  ? 309 LYS A NZ  1 
ATOM   2295  N N   . TYR A 1 310 ? 149.084 135.762 138.794 1.00 21.06  ? 310 TYR A N   1 
ATOM   2296  C CA  . TYR A 1 310 ? 149.543 137.120 138.542 1.00 21.06  ? 310 TYR A CA  1 
ATOM   2297  C C   . TYR A 1 310 ? 148.626 138.124 139.227 1.00 21.06  ? 310 TYR A C   1 
ATOM   2298  O O   . TYR A 1 310 ? 147.400 138.045 139.100 1.00 21.06  ? 310 TYR A O   1 
ATOM   2299  C CB  . TYR A 1 310 ? 149.600 137.402 137.040 1.00 21.06  ? 310 TYR A CB  1 
ATOM   2300  C CG  . TYR A 1 310 ? 150.107 138.784 136.709 1.00 21.06  ? 310 TYR A CG  1 
ATOM   2301  C CD1 . TYR A 1 310 ? 151.450 139.102 136.847 1.00 21.06  ? 310 TYR A CD1 1 
ATOM   2302  C CD2 . TYR A 1 310 ? 149.242 139.776 136.270 1.00 21.06  ? 310 TYR A CD2 1 
ATOM   2303  C CE1 . TYR A 1 310 ? 151.918 140.363 136.551 1.00 21.06  ? 310 TYR A CE1 1 
ATOM   2304  C CE2 . TYR A 1 310 ? 149.702 141.042 135.974 1.00 21.06  ? 310 TYR A CE2 1 
ATOM   2305  C CZ  . TYR A 1 310 ? 151.041 141.329 136.115 1.00 21.06  ? 310 TYR A CZ  1 
ATOM   2306  O OH  . TYR A 1 310 ? 151.506 142.587 135.821 1.00 21.06  ? 310 TYR A OH  1 
ATOM   2307  N N   . VAL A 1 311 ? 149.227 139.070 139.950 1.00 21.68  ? 311 VAL A N   1 
ATOM   2308  C CA  . VAL A 1 311 ? 148.499 140.139 140.618 1.00 21.68  ? 311 VAL A CA  1 
ATOM   2309  C C   . VAL A 1 311 ? 149.183 141.461 140.298 1.00 21.68  ? 311 VAL A C   1 
ATOM   2310  O O   . VAL A 1 311 ? 150.357 141.508 139.930 1.00 21.68  ? 311 VAL A O   1 
ATOM   2311  C CB  . VAL A 1 311 ? 148.414 139.930 142.146 1.00 21.68  ? 311 VAL A CB  1 
ATOM   2312  C CG1 . VAL A 1 311 ? 147.536 138.734 142.473 1.00 21.68  ? 311 VAL A CG1 1 
ATOM   2313  C CG2 . VAL A 1 311 ? 149.802 139.756 142.740 1.00 21.68  ? 311 VAL A CG2 1 
ATOM   2314  N N   . LYS A 1 312 ? 148.423 142.548 140.442 1.00 23.24  ? 312 LYS A N   1 
ATOM   2315  C CA  . LYS A 1 312 ? 148.955 143.879 140.175 1.00 23.24  ? 312 LYS A CA  1 
ATOM   2316  C C   . LYS A 1 312 ? 149.804 144.421 141.316 1.00 23.24  ? 312 LYS A C   1 
ATOM   2317  O O   . LYS A 1 312 ? 150.562 145.373 141.106 1.00 23.24  ? 312 LYS A O   1 
ATOM   2318  C CB  . LYS A 1 312 ? 147.814 144.858 139.890 1.00 23.24  ? 312 LYS A CB  1 
ATOM   2319  C CG  . LYS A 1 312 ? 147.149 144.669 138.542 1.00 23.24  ? 312 LYS A CG  1 
ATOM   2320  C CD  . LYS A 1 312 ? 146.048 145.693 138.329 1.00 23.24  ? 312 LYS A CD  1 
ATOM   2321  C CE  . LYS A 1 312 ? 144.812 145.350 139.141 1.00 23.24  ? 312 LYS A CE  1 
ATOM   2322  N NZ  . LYS A 1 312 ? 143.699 146.301 138.883 1.00 23.24  ? 312 LYS A NZ  1 
ATOM   2323  N N   . GLN A 1 313 ? 149.695 143.846 142.509 1.00 24.61  ? 313 GLN A N   1 
ATOM   2324  C CA  . GLN A 1 313 ? 150.442 144.335 143.657 1.00 24.61  ? 313 GLN A CA  1 
ATOM   2325  C C   . GLN A 1 313 ? 151.863 143.787 143.651 1.00 24.61  ? 313 GLN A C   1 
ATOM   2326  O O   . GLN A 1 313 ? 152.127 142.685 143.163 1.00 24.61  ? 313 GLN A O   1 
ATOM   2327  C CB  . GLN A 1 313 ? 149.741 143.946 144.959 1.00 24.61  ? 313 GLN A CB  1 
ATOM   2328  C CG  . GLN A 1 313 ? 148.344 144.522 145.104 1.00 24.61  ? 313 GLN A CG  1 
ATOM   2329  C CD  . GLN A 1 313 ? 147.262 143.493 144.860 1.00 24.61  ? 313 GLN A CD  1 
ATOM   2330  O OE1 . GLN A 1 313 ? 147.407 142.614 144.013 1.00 24.61  ? 313 GLN A OE1 1 
ATOM   2331  N NE2 . GLN A 1 313 ? 146.169 143.597 145.602 1.00 24.61  ? 313 GLN A NE2 1 
ATOM   2332  N N   . ASN A 1 314 ? 152.785 144.577 144.201 1.00 28.34  ? 314 ASN A N   1 
ATOM   2333  C CA  . ASN A 1 314 ? 154.181 144.175 144.294 1.00 28.34  ? 314 ASN A CA  1 
ATOM   2334  C C   . ASN A 1 314 ? 154.581 143.664 145.672 1.00 28.34  ? 314 ASN A C   1 
ATOM   2335  O O   . ASN A 1 314 ? 155.625 143.013 145.790 1.00 28.34  ? 314 ASN A O   1 
ATOM   2336  C CB  . ASN A 1 314 ? 155.097 145.338 143.881 1.00 28.34  ? 314 ASN A CB  1 
ATOM   2337  C CG  . ASN A 1 314 ? 154.985 146.541 144.803 1.00 28.34  ? 314 ASN A CG  1 
ATOM   2338  O OD1 . ASN A 1 314 ? 154.317 146.499 145.835 1.00 28.34  ? 314 ASN A OD1 1 
ATOM   2339  N ND2 . ASN A 1 314 ? 155.646 147.629 144.426 1.00 28.34  ? 314 ASN A ND2 1 
ATOM   2340  N N   . THR A 1 315 ? 153.788 143.932 146.706 1.00 27.94  ? 315 THR A N   1 
ATOM   2341  C CA  . THR A 1 315 ? 154.088 143.431 148.039 1.00 27.94  ? 315 THR A CA  1 
ATOM   2342  C C   . THR A 1 315 ? 152.791 143.102 148.768 1.00 27.94  ? 315 THR A C   1 
ATOM   2343  O O   . THR A 1 315 ? 151.813 143.848 148.686 1.00 27.94  ? 315 THR A O   1 
ATOM   2344  C CB  . THR A 1 315 ? 154.926 144.438 148.845 1.00 27.94  ? 315 THR A CB  1 
ATOM   2345  O OG1 . THR A 1 315 ? 155.224 143.895 150.138 1.00 27.94  ? 315 THR A OG1 1 
ATOM   2346  C CG2 . THR A 1 315 ? 154.201 145.766 149.004 1.00 27.94  ? 315 THR A CG2 1 
ATOM   2347  N N   . LEU A 1 316 ? 152.791 141.963 149.460 1.00 28.23  ? 316 LEU A N   1 
ATOM   2348  C CA  . LEU A 1 316 ? 151.668 141.552 150.301 1.00 28.23  ? 316 LEU A CA  1 
ATOM   2349  C C   . LEU A 1 316 ? 152.245 140.767 151.469 1.00 28.23  ? 316 LEU A C   1 
ATOM   2350  O O   . LEU A 1 316 ? 152.772 139.668 151.274 1.00 28.23  ? 316 LEU A O   1 
ATOM   2351  C CB  . LEU A 1 316 ? 150.659 140.711 149.522 1.00 28.23  ? 316 LEU A CB  1 
ATOM   2352  C CG  . LEU A 1 316 ? 149.646 141.423 148.621 1.00 28.23  ? 316 LEU A CG  1 
ATOM   2353  C CD1 . LEU A 1 316 ? 149.019 140.440 147.649 1.00 28.23  ? 316 LEU A CD1 1 
ATOM   2354  C CD2 . LEU A 1 316 ? 148.576 142.116 149.445 1.00 28.23  ? 316 LEU A CD2 1 
ATOM   2355  N N   . LYS A 1 317 ? 152.144 141.321 152.673 1.00 32.63  ? 317 LYS A N   1 
ATOM   2356  C CA  . LYS A 1 317 ? 152.741 140.728 153.863 1.00 32.63  ? 317 LYS A CA  1 
ATOM   2357  C C   . LYS A 1 317 ? 151.685 139.969 154.655 1.00 32.63  ? 317 LYS A C   1 
ATOM   2358  O O   . LYS A 1 317 ? 150.590 140.487 154.896 1.00 32.63  ? 317 LYS A O   1 
ATOM   2359  C CB  . LYS A 1 317 ? 153.384 141.803 154.739 1.00 32.63  ? 317 LYS A CB  1 
ATOM   2360  C CG  . LYS A 1 317 ? 154.322 142.732 153.991 1.00 32.63  ? 317 LYS A CG  1 
ATOM   2361  C CD  . LYS A 1 317 ? 155.629 142.041 153.656 1.00 32.63  ? 317 LYS A CD  1 
ATOM   2362  C CE  . LYS A 1 317 ? 156.557 142.011 154.855 1.00 32.63  ? 317 LYS A CE  1 
ATOM   2363  N NZ  . LYS A 1 317 ? 157.540 140.898 154.767 1.00 32.63  ? 317 LYS A NZ  1 
ATOM   2364  N N   . LEU A 1 318 ? 152.020 138.747 155.060 1.00 33.58  ? 318 LEU A N   1 
ATOM   2365  C CA  . LEU A 1 318 ? 151.137 137.899 155.850 1.00 33.58  ? 318 LEU A CA  1 
ATOM   2366  C C   . LEU A 1 318 ? 151.721 137.746 157.247 1.00 33.58  ? 318 LEU A C   1 
ATOM   2367  O O   . LEU A 1 318 ? 152.860 137.292 157.400 1.00 33.58  ? 318 LEU A O   1 
ATOM   2368  C CB  . LEU A 1 318 ? 150.957 136.533 155.187 1.00 33.58  ? 318 LEU A CB  1 
ATOM   2369  C CG  . LEU A 1 318 ? 149.960 135.578 155.844 1.00 33.58  ? 318 LEU A CG  1 
ATOM   2370  C CD1 . LEU A 1 318 ? 148.545 135.898 155.400 1.00 33.58  ? 318 LEU A CD1 1 
ATOM   2371  C CD2 . LEU A 1 318 ? 150.312 134.136 155.527 1.00 33.58  ? 318 LEU A CD2 1 
ATOM   2372  N N   . ALA A 1 319 ? 150.941 138.115 158.260 1.00 38.79  ? 319 ALA A N   1 
ATOM   2373  C CA  . ALA A 1 319 ? 151.415 138.053 159.636 1.00 38.79  ? 319 ALA A CA  1 
ATOM   2374  C C   . ALA A 1 319 ? 151.519 136.607 160.103 1.00 38.79  ? 319 ALA A C   1 
ATOM   2375  O O   . ALA A 1 319 ? 150.597 135.810 159.905 1.00 38.79  ? 319 ALA A O   1 
ATOM   2376  C CB  . ALA A 1 319 ? 150.481 138.837 160.555 1.00 38.79  ? 319 ALA A CB  1 
ATOM   2377  N N   . THR A 1 320 ? 152.650 136.269 160.725 1.00 42.22  ? 320 THR A N   1 
ATOM   2378  C CA  . THR A 1 320 ? 152.871 134.941 161.288 1.00 42.22  ? 320 THR A CA  1 
ATOM   2379  C C   . THR A 1 320 ? 153.212 135.003 162.773 1.00 42.22  ? 320 THR A C   1 
ATOM   2380  O O   . THR A 1 320 ? 153.837 134.079 163.302 1.00 42.22  ? 320 THR A O   1 
ATOM   2381  C CB  . THR A 1 320 ? 153.973 134.203 160.523 1.00 42.22  ? 320 THR A CB  1 
ATOM   2382  O OG1 . THR A 1 320 ? 155.235 134.835 160.764 1.00 42.22  ? 320 THR A OG1 1 
ATOM   2383  C CG2 . THR A 1 320 ? 153.689 134.208 159.030 1.00 42.22  ? 320 THR A CG2 1 
ATOM   2384  N N   . GLY A 1 321 ? 152.816 136.075 163.457 1.00 43.92  ? 321 GLY A N   1 
ATOM   2385  C CA  . GLY A 1 321 ? 153.072 136.229 164.872 1.00 43.92  ? 321 GLY A CA  1 
ATOM   2386  C C   . GLY A 1 321 ? 152.035 137.131 165.503 1.00 43.92  ? 321 GLY A C   1 
ATOM   2387  O O   . GLY A 1 321 ? 151.099 137.591 164.847 1.00 43.92  ? 321 GLY A O   1 
ATOM   2388  N N   . MET A 1 322 ? 152.210 137.384 166.798 1.00 46.12  ? 322 MET A N   1 
ATOM   2389  C CA  . MET A 1 322 ? 151.300 138.235 167.545 1.00 46.12  ? 322 MET A CA  1 
ATOM   2390  C C   . MET A 1 322 ? 151.737 139.694 167.439 1.00 46.12  ? 322 MET A C   1 
ATOM   2391  O O   . MET A 1 322 ? 152.698 140.035 166.748 1.00 46.12  ? 322 MET A O   1 
ATOM   2392  C CB  . MET A 1 322 ? 151.232 137.796 169.007 1.00 46.12  ? 322 MET A CB  1 
ATOM   2393  C CG  . MET A 1 322 ? 152.542 137.953 169.760 1.00 46.12  ? 322 MET A CG  1 
ATOM   2394  S SD  . MET A 1 322 ? 152.463 137.337 171.450 1.00 46.12  ? 322 MET A SD  1 
ATOM   2395  C CE  . MET A 1 322 ? 152.450 135.573 171.164 1.00 46.12  ? 322 MET A CE  1 
ATOM   2396  N N   . ARG A 1 323 ? 151.019 140.569 168.139 1.00 48.94  ? 323 ARG A N   1 
ATOM   2397  C CA  . ARG A 1 323 ? 151.366 141.983 168.150 1.00 48.94  ? 323 ARG A CA  1 
ATOM   2398  C C   . ARG A 1 323 ? 152.710 142.203 168.833 1.00 48.94  ? 323 ARG A C   1 
ATOM   2399  O O   . ARG A 1 323 ? 153.119 141.442 169.714 1.00 48.94  ? 323 ARG A O   1 
ATOM   2400  C CB  . ARG A 1 323 ? 150.292 142.797 168.870 1.00 48.94  ? 323 ARG A CB  1 
ATOM   2401  C CG  . ARG A 1 323 ? 148.958 142.855 168.162 1.00 48.94  ? 323 ARG A CG  1 
ATOM   2402  C CD  . ARG A 1 323 ? 147.970 143.684 168.963 1.00 48.94  ? 323 ARG A CD  1 
ATOM   2403  N NE  . ARG A 1 323 ? 146.662 143.747 168.324 1.00 48.94  ? 323 ARG A NE  1 
ATOM   2404  C CZ  . ARG A 1 323 ? 145.607 144.360 168.841 1.00 48.94  ? 323 ARG A CZ  1 
ATOM   2405  N NH1 . ARG A 1 323 ? 145.673 144.982 170.007 1.00 48.94  ? 323 ARG A NH1 1 
ATOM   2406  N NH2 . ARG A 1 323 ? 144.458 144.350 168.172 1.00 48.94  ? 323 ARG A NH2 1 
ATOM   2407  N N   . ASN A 1 324 ? 153.400 143.259 168.415 1.00 52.50  ? 324 ASN A N   1 
ATOM   2408  C CA  . ASN A 1 324 ? 154.651 143.677 169.035 1.00 52.50  ? 324 ASN A CA  1 
ATOM   2409  C C   . ASN A 1 324 ? 154.363 144.898 169.900 1.00 52.50  ? 324 ASN A C   1 
ATOM   2410  O O   . ASN A 1 324 ? 154.058 145.977 169.382 1.00 52.50  ? 324 ASN A O   1 
ATOM   2411  C CB  . ASN A 1 324 ? 155.710 143.980 167.979 1.00 52.50  ? 324 ASN A CB  1 
ATOM   2412  C CG  . ASN A 1 324 ? 157.114 143.736 168.481 1.00 52.50  ? 324 ASN A CG  1 
ATOM   2413  O OD1 . ASN A 1 324 ? 157.398 142.700 169.079 1.00 52.50  ? 324 ASN A OD1 1 
ATOM   2414  N ND2 . ASN A 1 324 ? 158.004 144.690 168.242 1.00 52.50  ? 324 ASN A ND2 1 
ATOM   2415  N N   . VAL A 1 325 ? 154.455 144.725 171.215 1.00 61.06  ? 325 VAL A N   1 
ATOM   2416  C CA  . VAL A 1 325 ? 154.145 145.769 172.182 1.00 61.06  ? 325 VAL A CA  1 
ATOM   2417  C C   . VAL A 1 325 ? 155.412 146.062 172.974 1.00 61.06  ? 325 VAL A C   1 
ATOM   2418  O O   . VAL A 1 325 ? 155.985 145.144 173.564 1.00 61.06  ? 325 VAL A O   1 
ATOM   2419  C CB  . VAL A 1 325 ? 153.002 145.369 173.132 1.00 61.06  ? 325 VAL A CB  1 
ATOM   2420  C CG1 . VAL A 1 325 ? 152.950 146.305 174.328 1.00 61.06  ? 325 VAL A CG1 1 
ATOM   2421  C CG2 . VAL A 1 325 ? 151.675 145.366 172.392 1.00 61.06  ? 325 VAL A CG2 1 
ATOM   2422  N N   . PRO A 1 326 ? 155.886 147.305 173.009 1.00 63.77  ? 326 PRO A N   1 
ATOM   2423  C CA  . PRO A 1 326 ? 157.086 147.615 173.793 1.00 63.77  ? 326 PRO A CA  1 
ATOM   2424  C C   . PRO A 1 326 ? 156.835 147.460 175.284 1.00 63.77  ? 326 PRO A C   1 
ATOM   2425  O O   . PRO A 1 326 ? 155.719 147.640 175.775 1.00 63.77  ? 326 PRO A O   1 
ATOM   2426  C CB  . PRO A 1 326 ? 157.386 149.076 173.431 1.00 63.77  ? 326 PRO A CB  1 
ATOM   2427  C CG  . PRO A 1 326 ? 156.531 149.381 172.230 1.00 63.77  ? 326 PRO A CG  1 
ATOM   2428  C CD  . PRO A 1 326 ? 155.338 148.495 172.341 1.00 63.77  ? 326 PRO A CD  1 
ATOM   2429  N N   . GLU A 1 327 ? 157.899 147.122 176.007 1.00 66.61  ? 327 GLU A N   1 
ATOM   2430  C CA  . GLU A 1 327 ? 157.811 146.941 177.451 1.00 66.61  ? 327 GLU A CA  1 
ATOM   2431  C C   . GLU A 1 327 ? 157.593 148.274 178.161 1.00 66.61  ? 327 GLU A C   1 
ATOM   2432  O O   . GLU A 1 327 ? 158.548 148.966 178.512 1.00 66.61  ? 327 GLU A O   1 
ATOM   2433  C CB  . GLU A 1 327 ? 159.072 146.260 177.987 1.00 66.61  ? 327 GLU A CB  1 
ATOM   2434  C CG  . GLU A 1 327 ? 158.947 145.783 179.427 1.00 66.61  ? 327 GLU A CG  1 
ATOM   2435  C CD  . GLU A 1 327 ? 159.902 144.652 179.755 1.00 66.61  ? 327 GLU A CD  1 
ATOM   2436  O OE1 . GLU A 1 327 ? 160.767 144.339 178.912 1.00 66.61  ? 327 GLU A OE1 1 
ATOM   2437  O OE2 . GLU A 1 327 ? 159.785 144.073 180.855 1.00 66.61  ? 327 GLU A OE2 1 
ATOM   2438  N N   . ILE A 1 337 ? 157.419 143.797 188.794 1.00 77.14  ? 337 ILE A N   1 
ATOM   2439  C CA  . ILE A 1 337 ? 157.022 143.044 187.612 1.00 77.14  ? 337 ILE A CA  1 
ATOM   2440  C C   . ILE A 1 337 ? 155.606 143.419 187.193 1.00 77.14  ? 337 ILE A C   1 
ATOM   2441  O O   . ILE A 1 337 ? 154.762 143.736 188.031 1.00 77.14  ? 337 ILE A O   1 
ATOM   2442  C CB  . ILE A 1 337 ? 157.140 141.528 187.854 1.00 77.14  ? 337 ILE A CB  1 
ATOM   2443  C CG1 . ILE A 1 337 ? 156.367 141.123 189.110 1.00 77.14  ? 337 ILE A CG1 1 
ATOM   2444  C CG2 . ILE A 1 337 ? 158.600 141.117 187.970 1.00 77.14  ? 337 ILE A CG2 1 
ATOM   2445  C CD1 . ILE A 1 337 ? 156.341 139.632 189.351 1.00 77.14  ? 337 ILE A CD1 1 
ATOM   2446  N N   . ALA A 1 338 ? 155.353 143.380 185.887 1.00 74.47  ? 338 ALA A N   1 
ATOM   2447  C CA  . ALA A 1 338 ? 154.056 143.712 185.318 1.00 74.47  ? 338 ALA A CA  1 
ATOM   2448  C C   . ALA A 1 338 ? 153.643 142.619 184.343 1.00 74.47  ? 338 ALA A C   1 
ATOM   2449  O O   . ALA A 1 338 ? 154.474 141.865 183.830 1.00 74.47  ? 338 ALA A O   1 
ATOM   2450  C CB  . ALA A 1 338 ? 154.082 145.076 184.618 1.00 74.47  ? 338 ALA A CB  1 
ATOM   2451  N N   . GLY A 1 339 ? 152.345 142.540 184.086 1.00 70.37  ? 339 GLY A N   1 
ATOM   2452  C CA  . GLY A 1 339 ? 151.761 141.509 183.255 1.00 70.37  ? 339 GLY A CA  1 
ATOM   2453  C C   . GLY A 1 339 ? 151.694 141.895 181.793 1.00 70.37  ? 339 GLY A C   1 
ATOM   2454  O O   . GLY A 1 339 ? 152.526 142.656 181.287 1.00 70.37  ? 339 GLY A O   1 
ATOM   2455  N N   . PHE A 1 340 ? 150.688 141.362 181.103 1.00 66.78  ? 340 PHE A N   1 
ATOM   2456  C CA  . PHE A 1 340 ? 150.537 141.542 179.665 1.00 66.78  ? 340 PHE A CA  1 
ATOM   2457  C C   . PHE A 1 340 ? 149.650 142.722 179.292 1.00 66.78  ? 340 PHE A C   1 
ATOM   2458  O O   . PHE A 1 340 ? 149.429 142.955 178.099 1.00 66.78  ? 340 PHE A O   1 
ATOM   2459  C CB  . PHE A 1 340 ? 149.977 140.264 179.031 1.00 66.78  ? 340 PHE A CB  1 
ATOM   2460  C CG  . PHE A 1 340 ? 148.553 139.967 179.413 1.00 66.78  ? 340 PHE A CG  1 
ATOM   2461  C CD1 . PHE A 1 340 ? 148.259 139.352 180.618 1.00 66.78  ? 340 PHE A CD1 1 
ATOM   2462  C CD2 . PHE A 1 340 ? 147.510 140.296 178.564 1.00 66.78  ? 340 PHE A CD2 1 
ATOM   2463  C CE1 . PHE A 1 340 ? 146.954 139.077 180.970 1.00 66.78  ? 340 PHE A CE1 1 
ATOM   2464  C CE2 . PHE A 1 340 ? 146.203 140.023 178.912 1.00 66.78  ? 340 PHE A CE2 1 
ATOM   2465  C CZ  . PHE A 1 340 ? 145.925 139.412 180.116 1.00 66.78  ? 340 PHE A CZ  1 
ATOM   2466  N N   . ILE A 1 341 ? 149.140 143.470 180.268 1.00 70.70  ? 341 ILE A N   1 
ATOM   2467  C CA  . ILE A 1 341 ? 148.253 144.593 179.984 1.00 70.70  ? 341 ILE A CA  1 
ATOM   2468  C C   . ILE A 1 341 ? 149.081 145.744 179.427 1.00 70.70  ? 341 ILE A C   1 
ATOM   2469  O O   . ILE A 1 341 ? 149.706 146.497 180.183 1.00 70.70  ? 341 ILE A O   1 
ATOM   2470  C CB  . ILE A 1 341 ? 147.473 145.011 181.245 1.00 70.70  ? 341 ILE A CB  1 
ATOM   2471  C CG1 . ILE A 1 341 ? 146.587 143.860 181.725 1.00 70.70  ? 341 ILE A CG1 1 
ATOM   2472  C CG2 . ILE A 1 341 ? 146.625 146.239 180.978 1.00 70.70  ? 341 ILE A CG2 1 
ATOM   2473  C CD1 . ILE A 1 341 ? 145.467 143.511 180.770 1.00 70.70  ? 341 ILE A CD1 1 
ATOM   2474  N N   . GLU A 1 342 ? 149.084 145.882 178.099 1.00 71.91  ? 342 GLU A N   1 
ATOM   2475  C CA  . GLU A 1 342 ? 149.925 146.851 177.392 1.00 71.91  ? 342 GLU A CA  1 
ATOM   2476  C C   . GLU A 1 342 ? 151.374 146.781 177.870 1.00 71.91  ? 342 GLU A C   1 
ATOM   2477  O O   . GLU A 1 342 ? 151.951 147.762 178.343 1.00 71.91  ? 342 GLU A O   1 
ATOM   2478  C CB  . GLU A 1 342 ? 149.368 148.269 177.521 1.00 71.91  ? 342 GLU A CB  1 
ATOM   2479  C CG  . GLU A 1 342 ? 148.233 148.579 176.554 1.00 71.91  ? 342 GLU A CG  1 
ATOM   2480  C CD  . GLU A 1 342 ? 146.879 148.138 177.066 1.00 71.91  ? 342 GLU A CD  1 
ATOM   2481  O OE1 . GLU A 1 342 ? 146.809 147.649 178.210 1.00 71.91  ? 342 GLU A OE1 1 
ATOM   2482  O OE2 . GLU A 1 342 ? 145.885 148.280 176.324 1.00 71.91  ? 342 GLU A OE2 1 
ATOM   2483  N N   . ASN A 1 343 ? 151.965 145.595 177.737 1.00 68.05  ? 343 ASN A N   1 
ATOM   2484  C CA  . ASN A 1 343 ? 153.340 145.376 178.167 1.00 68.05  ? 343 ASN A CA  1 
ATOM   2485  C C   . ASN A 1 343 ? 153.853 144.091 177.538 1.00 68.05  ? 343 ASN A C   1 
ATOM   2486  O O   . ASN A 1 343 ? 153.227 143.037 177.680 1.00 68.05  ? 343 ASN A O   1 
ATOM   2487  C CB  . ASN A 1 343 ? 153.430 145.300 179.695 1.00 68.05  ? 343 ASN A CB  1 
ATOM   2488  C CG  . ASN A 1 343 ? 154.857 145.331 180.197 1.00 68.05  ? 343 ASN A CG  1 
ATOM   2489  O OD1 . ASN A 1 343 ? 155.630 146.222 179.849 1.00 68.05  ? 343 ASN A OD1 1 
ATOM   2490  N ND2 . ASN A 1 343 ? 155.214 144.358 181.025 1.00 68.05  ? 343 ASN A ND2 1 
ATOM   2491  N N   . GLY A 1 344 ? 154.986 144.182 176.847 1.00 66.39  ? 344 GLY A N   1 
ATOM   2492  C CA  . GLY A 1 344 ? 155.625 143.011 176.281 1.00 66.39  ? 344 GLY A CA  1 
ATOM   2493  C C   . GLY A 1 344 ? 156.872 142.627 177.048 1.00 66.39  ? 344 GLY A C   1 
ATOM   2494  O O   . GLY A 1 344 ? 157.455 143.461 177.744 1.00 66.39  ? 344 GLY A O   1 
ATOM   2495  N N   . TRP A 1 345 ? 157.291 141.371 176.938 1.00 66.03  ? 345 TRP A N   1 
ATOM   2496  C CA  . TRP A 1 345 ? 158.462 140.863 177.648 1.00 66.03  ? 345 TRP A CA  1 
ATOM   2497  C C   . TRP A 1 345 ? 159.534 140.524 176.618 1.00 66.03  ? 345 TRP A C   1 
ATOM   2498  O O   . TRP A 1 345 ? 159.494 139.460 175.996 1.00 66.03  ? 345 TRP A O   1 
ATOM   2499  C CB  . TRP A 1 345 ? 158.100 139.647 178.495 1.00 66.03  ? 345 TRP A CB  1 
ATOM   2500  C CG  . TRP A 1 345 ? 157.219 139.963 179.665 1.00 66.03  ? 345 TRP A CG  1 
ATOM   2501  C CD1 . TRP A 1 345 ? 156.840 141.200 180.097 1.00 66.03  ? 345 TRP A CD1 1 
ATOM   2502  C CD2 . TRP A 1 345 ? 156.604 139.023 180.552 1.00 66.03  ? 345 TRP A CD2 1 
ATOM   2503  N NE1 . TRP A 1 345 ? 156.028 141.088 181.198 1.00 66.03  ? 345 TRP A NE1 1 
ATOM   2504  C CE2 . TRP A 1 345 ? 155.868 139.761 181.498 1.00 66.03  ? 345 TRP A CE2 1 
ATOM   2505  C CE3 . TRP A 1 345 ? 156.605 137.628 180.640 1.00 66.03  ? 345 TRP A CE3 1 
ATOM   2506  C CZ2 . TRP A 1 345 ? 155.141 139.152 182.516 1.00 66.03  ? 345 TRP A CZ2 1 
ATOM   2507  C CZ3 . TRP A 1 345 ? 155.884 137.026 181.650 1.00 66.03  ? 345 TRP A CZ3 1 
ATOM   2508  C CH2 . TRP A 1 345 ? 155.162 137.787 182.575 1.00 66.03  ? 345 TRP A CH2 1 
ATOM   2509  N N   . GLU A 1 346 ? 160.499 141.427 176.448 1.00 70.50  ? 346 GLU A N   1 
ATOM   2510  C CA  . GLU A 1 346 ? 161.585 141.194 175.506 1.00 70.50  ? 346 GLU A CA  1 
ATOM   2511  C C   . GLU A 1 346 ? 162.613 140.197 176.023 1.00 70.50  ? 346 GLU A C   1 
ATOM   2512  O O   . GLU A 1 346 ? 163.484 139.777 175.254 1.00 70.50  ? 346 GLU A O   1 
ATOM   2513  C CB  . GLU A 1 346 ? 162.277 142.515 175.159 1.00 70.50  ? 346 GLU A CB  1 
ATOM   2514  C CG  . GLU A 1 346 ? 162.481 143.442 176.342 1.00 70.50  ? 346 GLU A CG  1 
ATOM   2515  C CD  . GLU A 1 346 ? 163.233 144.704 175.970 1.00 70.50  ? 346 GLU A CD  1 
ATOM   2516  O OE1 . GLU A 1 346 ? 162.993 145.238 174.867 1.00 70.50  ? 346 GLU A OE1 1 
ATOM   2517  O OE2 . GLU A 1 346 ? 164.064 145.164 176.781 1.00 70.50  ? 346 GLU A OE2 1 
ATOM   2518  N N   . GLY A 1 347 ? 162.533 139.810 177.290 1.00 72.72  ? 347 GLY A N   1 
ATOM   2519  C CA  . GLY A 1 347 ? 163.427 138.835 177.873 1.00 72.72  ? 347 GLY A CA  1 
ATOM   2520  C C   . GLY A 1 347 ? 162.949 137.402 177.804 1.00 72.72  ? 347 GLY A C   1 
ATOM   2521  O O   . GLY A 1 347 ? 163.487 136.550 178.519 1.00 72.72  ? 347 GLY A O   1 
ATOM   2522  N N   . MET A 1 348 ? 161.956 137.105 176.969 1.00 69.74  ? 348 MET A N   1 
ATOM   2523  C CA  . MET A 1 348 ? 161.421 135.757 176.830 1.00 69.74  ? 348 MET A CA  1 
ATOM   2524  C C   . MET A 1 348 ? 161.909 135.155 175.519 1.00 69.74  ? 348 MET A C   1 
ATOM   2525  O O   . MET A 1 348 ? 161.580 135.656 174.439 1.00 69.74  ? 348 MET A O   1 
ATOM   2526  C CB  . MET A 1 348 ? 159.893 135.767 176.877 1.00 69.74  ? 348 MET A CB  1 
ATOM   2527  C CG  . MET A 1 348 ? 159.273 134.380 176.855 1.00 69.74  ? 348 MET A CG  1 
ATOM   2528  S SD  . MET A 1 348 ? 157.473 134.409 176.922 1.00 69.74  ? 348 MET A SD  1 
ATOM   2529  C CE  . MET A 1 348 ? 157.209 134.904 178.618 1.00 69.74  ? 348 MET A CE  1 
ATOM   2530  N N   . ILE A 1 349 ? 162.690 134.080 175.618 1.00 72.60  ? 349 ILE A N   1 
ATOM   2531  C CA  . ILE A 1 349 ? 163.226 133.382 174.457 1.00 72.60  ? 349 ILE A CA  1 
ATOM   2532  C C   . ILE A 1 349 ? 162.845 131.911 174.432 1.00 72.60  ? 349 ILE A C   1 
ATOM   2533  O O   . ILE A 1 349 ? 163.167 131.217 173.462 1.00 72.60  ? 349 ILE A O   1 
ATOM   2534  C CB  . ILE A 1 349 ? 164.759 133.533 174.370 1.00 72.60  ? 349 ILE A CB  1 
ATOM   2535  C CG1 . ILE A 1 349 ? 165.423 132.930 175.610 1.00 72.60  ? 349 ILE A CG1 1 
ATOM   2536  C CG2 . ILE A 1 349 ? 165.144 134.996 174.211 1.00 72.60  ? 349 ILE A CG2 1 
ATOM   2537  C CD1 . ILE A 1 349 ? 166.921 132.770 175.484 1.00 72.60  ? 349 ILE A CD1 1 
ATOM   2538  N N   . ASP A 1 350 ? 162.171 131.410 175.468 1.00 72.18  ? 350 ASP A N   1 
ATOM   2539  C CA  . ASP A 1 350 ? 161.814 130.001 175.552 1.00 72.18  ? 350 ASP A CA  1 
ATOM   2540  C C   . ASP A 1 350 ? 160.461 129.682 174.931 1.00 72.18  ? 350 ASP A C   1 
ATOM   2541  O O   . ASP A 1 350 ? 160.251 128.546 174.493 1.00 72.18  ? 350 ASP A O   1 
ATOM   2542  C CB  . ASP A 1 350 ? 161.813 129.547 177.018 1.00 72.18  ? 350 ASP A CB  1 
ATOM   2543  C CG  . ASP A 1 350 ? 162.174 128.081 177.180 1.00 72.18  ? 350 ASP A CG  1 
ATOM   2544  O OD1 . ASP A 1 350 ? 161.850 127.274 176.285 1.00 72.18  ? 350 ASP A OD1 1 
ATOM   2545  O OD2 . ASP A 1 350 ? 162.789 127.735 178.211 1.00 72.18  ? 350 ASP A OD2 1 
ATOM   2546  N N   . GLY A 1 351 ? 159.552 130.646 174.871 1.00 67.34  ? 351 GLY A N   1 
ATOM   2547  C CA  . GLY A 1 351 ? 158.229 130.384 174.335 1.00 67.34  ? 351 GLY A CA  1 
ATOM   2548  C C   . GLY A 1 351 ? 157.497 131.682 174.083 1.00 67.34  ? 351 GLY A C   1 
ATOM   2549  O O   . GLY A 1 351 ? 158.045 132.776 174.245 1.00 67.34  ? 351 GLY A O   1 
ATOM   2550  N N   . TRP A 1 352 ? 156.238 131.541 173.670 1.00 58.59  ? 352 TRP A N   1 
ATOM   2551  C CA  . TRP A 1 352 ? 155.409 132.698 173.356 1.00 58.59  ? 352 TRP A CA  1 
ATOM   2552  C C   . TRP A 1 352 ? 154.714 133.271 174.585 1.00 58.59  ? 352 TRP A C   1 
ATOM   2553  O O   . TRP A 1 352 ? 154.563 134.492 174.695 1.00 58.59  ? 352 TRP A O   1 
ATOM   2554  C CB  . TRP A 1 352 ? 154.374 132.331 172.288 1.00 58.59  ? 352 TRP A CB  1 
ATOM   2555  C CG  . TRP A 1 352 ? 154.959 132.193 170.912 1.00 58.59  ? 352 TRP A CG  1 
ATOM   2556  C CD1 . TRP A 1 352 ? 156.257 131.916 170.597 1.00 58.59  ? 352 TRP A CD1 1 
ATOM   2557  C CD2 . TRP A 1 352 ? 154.265 132.329 169.665 1.00 58.59  ? 352 TRP A CD2 1 
ATOM   2558  N NE1 . TRP A 1 352 ? 156.415 131.870 169.233 1.00 58.59  ? 352 TRP A NE1 1 
ATOM   2559  C CE2 . TRP A 1 352 ? 155.207 132.120 168.638 1.00 58.59  ? 352 TRP A CE2 1 
ATOM   2560  C CE3 . TRP A 1 352 ? 152.940 132.606 169.317 1.00 58.59  ? 352 TRP A CE3 1 
ATOM   2561  C CZ2 . TRP A 1 352 ? 154.867 132.181 167.289 1.00 58.59  ? 352 TRP A CZ2 1 
ATOM   2562  C CZ3 . TRP A 1 352 ? 152.604 132.665 167.978 1.00 58.59  ? 352 TRP A CZ3 1 
ATOM   2563  C CH2 . TRP A 1 352 ? 153.563 132.454 166.980 1.00 58.59  ? 352 TRP A CH2 1 
ATOM   2564  N N   . TYR A 1 353 ? 154.290 132.415 175.513 1.00 59.15  ? 353 TYR A N   1 
ATOM   2565  C CA  . TYR A 1 353 ? 153.624 132.842 176.734 1.00 59.15  ? 353 TYR A CA  1 
ATOM   2566  C C   . TYR A 1 353 ? 154.288 132.174 177.929 1.00 59.15  ? 353 TYR A C   1 
ATOM   2567  O O   . TYR A 1 353 ? 154.831 131.072 177.820 1.00 59.15  ? 353 TYR A O   1 
ATOM   2568  C CB  . TYR A 1 353 ? 152.125 132.505 176.705 1.00 59.15  ? 353 TYR A CB  1 
ATOM   2569  C CG  . TYR A 1 353 ? 151.435 132.881 175.412 1.00 59.15  ? 353 TYR A CG  1 
ATOM   2570  C CD1 . TYR A 1 353 ? 150.910 134.152 175.227 1.00 59.15  ? 353 TYR A CD1 1 
ATOM   2571  C CD2 . TYR A 1 353 ? 151.310 131.965 174.376 1.00 59.15  ? 353 TYR A CD2 1 
ATOM   2572  C CE1 . TYR A 1 353 ? 150.280 134.500 174.049 1.00 59.15  ? 353 TYR A CE1 1 
ATOM   2573  C CE2 . TYR A 1 353 ? 150.684 132.305 173.194 1.00 59.15  ? 353 TYR A CE2 1 
ATOM   2574  C CZ  . TYR A 1 353 ? 150.170 133.573 173.036 1.00 59.15  ? 353 TYR A CZ  1 
ATOM   2575  O OH  . TYR A 1 353 ? 149.545 133.915 171.861 1.00 59.15  ? 353 TYR A OH  1 
ATOM   2576  N N   . GLY A 1 354 ? 154.241 132.850 179.074 1.00 66.06  ? 354 GLY A N   1 
ATOM   2577  C CA  . GLY A 1 354 ? 154.881 132.321 180.262 1.00 66.06  ? 354 GLY A CA  1 
ATOM   2578  C C   . GLY A 1 354 ? 154.456 133.070 181.505 1.00 66.06  ? 354 GLY A C   1 
ATOM   2579  O O   . GLY A 1 354 ? 153.595 133.952 181.467 1.00 66.06  ? 354 GLY A O   1 
ATOM   2580  N N   . PHE A 1 355 ? 155.081 132.701 182.621 1.00 69.95  ? 355 PHE A N   1 
ATOM   2581  C CA  . PHE A 1 355 ? 154.778 133.267 183.926 1.00 69.95  ? 355 PHE A CA  1 
ATOM   2582  C C   . PHE A 1 355 ? 156.011 133.945 184.509 1.00 69.95  ? 355 PHE A C   1 
ATOM   2583  O O   . PHE A 1 355 ? 157.146 133.528 184.263 1.00 69.95  ? 355 PHE A O   1 
ATOM   2584  C CB  . PHE A 1 355 ? 154.289 132.192 184.910 1.00 69.95  ? 355 PHE A CB  1 
ATOM   2585  C CG  . PHE A 1 355 ? 153.097 131.416 184.429 1.00 69.95  ? 355 PHE A CG  1 
ATOM   2586  C CD1 . PHE A 1 355 ? 153.253 130.321 183.596 1.00 69.95  ? 355 PHE A CD1 1 
ATOM   2587  C CD2 . PHE A 1 355 ? 151.820 131.771 184.825 1.00 69.95  ? 355 PHE A CD2 1 
ATOM   2588  C CE1 . PHE A 1 355 ? 152.159 129.604 183.159 1.00 69.95  ? 355 PHE A CE1 1 
ATOM   2589  C CE2 . PHE A 1 355 ? 150.723 131.057 184.392 1.00 69.95  ? 355 PHE A CE2 1 
ATOM   2590  C CZ  . PHE A 1 355 ? 150.893 129.972 183.558 1.00 69.95  ? 355 PHE A CZ  1 
ATOM   2591  N N   . ARG A 1 356 ? 155.772 134.997 185.289 1.00 70.39  ? 356 ARG A N   1 
ATOM   2592  C CA  . ARG A 1 356 ? 156.804 135.653 186.081 1.00 70.39  ? 356 ARG A CA  1 
ATOM   2593  C C   . ARG A 1 356 ? 156.275 135.833 187.494 1.00 70.39  ? 356 ARG A C   1 
ATOM   2594  O O   . ARG A 1 356 ? 155.142 136.288 187.678 1.00 70.39  ? 356 ARG A O   1 
ATOM   2595  C CB  . ARG A 1 356 ? 157.199 137.009 185.488 1.00 70.39  ? 356 ARG A CB  1 
ATOM   2596  C CG  . ARG A 1 356 ? 158.324 136.951 184.474 1.00 70.39  ? 356 ARG A CG  1 
ATOM   2597  C CD  . ARG A 1 356 ? 158.766 138.351 184.082 1.00 70.39  ? 356 ARG A CD  1 
ATOM   2598  N NE  . ARG A 1 356 ? 159.625 138.348 182.904 1.00 70.39  ? 356 ARG A NE  1 
ATOM   2599  C CZ  . ARG A 1 356 ? 159.999 139.439 182.250 1.00 70.39  ? 356 ARG A CZ  1 
ATOM   2600  N NH1 . ARG A 1 356 ? 159.613 140.643 182.637 1.00 70.39  ? 356 ARG A NH1 1 
ATOM   2601  N NH2 . ARG A 1 356 ? 160.779 139.318 181.180 1.00 70.39  ? 356 ARG A NH2 1 
ATOM   2602  N N   . HIS A 1 357 ? 157.088 135.483 188.486 1.00 79.02  ? 357 HIS A N   1 
ATOM   2603  C CA  . HIS A 1 357 ? 156.656 135.523 189.875 1.00 79.02  ? 357 HIS A CA  1 
ATOM   2604  C C   . HIS A 1 357 ? 157.675 136.259 190.730 1.00 79.02  ? 357 HIS A C   1 
ATOM   2605  O O   . HIS A 1 357 ? 158.882 136.176 190.488 1.00 79.02  ? 357 HIS A O   1 
ATOM   2606  C CB  . HIS A 1 357 ? 156.433 134.108 190.430 1.00 79.02  ? 357 HIS A CB  1 
ATOM   2607  C CG  . HIS A 1 357 ? 157.686 133.300 190.558 1.00 79.02  ? 357 HIS A CG  1 
ATOM   2608  N ND1 . HIS A 1 357 ? 158.081 132.384 189.608 1.00 79.02  ? 357 HIS A ND1 1 
ATOM   2609  C CD2 . HIS A 1 357 ? 158.626 133.260 191.532 1.00 79.02  ? 357 HIS A CD2 1 
ATOM   2610  C CE1 . HIS A 1 357 ? 159.214 131.820 189.986 1.00 79.02  ? 357 HIS A CE1 1 
ATOM   2611  N NE2 . HIS A 1 357 ? 159.566 132.334 191.151 1.00 79.02  ? 357 HIS A NE2 1 
ATOM   2612  N N   . GLN A 1 358 ? 157.175 136.983 191.728 1.00 83.84  ? 358 GLN A N   1 
ATOM   2613  C CA  . GLN A 1 358 ? 157.996 137.640 192.736 1.00 83.84  ? 358 GLN A CA  1 
ATOM   2614  C C   . GLN A 1 358 ? 157.737 136.957 194.072 1.00 83.84  ? 358 GLN A C   1 
ATOM   2615  O O   . GLN A 1 358 ? 156.612 136.991 194.581 1.00 83.84  ? 358 GLN A O   1 
ATOM   2616  C CB  . GLN A 1 358 ? 157.680 139.133 192.817 1.00 83.84  ? 358 GLN A CB  1 
ATOM   2617  C CG  . GLN A 1 358 ? 158.753 139.961 193.505 1.00 83.84  ? 358 GLN A CG  1 
ATOM   2618  C CD  . GLN A 1 358 ? 158.974 141.301 192.832 1.00 83.84  ? 358 GLN A CD  1 
ATOM   2619  O OE1 . GLN A 1 358 ? 158.091 141.820 192.150 1.00 83.84  ? 358 GLN A OE1 1 
ATOM   2620  N NE2 . GLN A 1 358 ? 160.159 141.869 193.020 1.00 83.84  ? 358 GLN A NE2 1 
ATOM   2621  N N   . ASN A 1 359 ? 158.774 136.346 194.636 1.00 91.14  ? 359 ASN A N   1 
ATOM   2622  C CA  . ASN A 1 359 ? 158.643 135.522 195.826 1.00 91.14  ? 359 ASN A CA  1 
ATOM   2623  C C   . ASN A 1 359 ? 159.682 135.938 196.857 1.00 91.14  ? 359 ASN A C   1 
ATOM   2624  O O   . ASN A 1 359 ? 160.571 136.751 196.588 1.00 91.14  ? 359 ASN A O   1 
ATOM   2625  C CB  . ASN A 1 359 ? 158.794 134.034 195.483 1.00 91.14  ? 359 ASN A CB  1 
ATOM   2626  C CG  . ASN A 1 359 ? 158.122 133.130 196.493 1.00 91.14  ? 359 ASN A CG  1 
ATOM   2627  O OD1 . ASN A 1 359 ? 157.424 133.596 197.393 1.00 91.14  ? 359 ASN A OD1 1 
ATOM   2628  N ND2 . ASN A 1 359 ? 158.330 131.828 196.350 1.00 91.14  ? 359 ASN A ND2 1 
ATOM   2629  N N   . SER A 1 360 ? 159.554 135.371 198.059 1.00 93.51  ? 360 SER A N   1 
ATOM   2630  C CA  . SER A 1 360 ? 160.531 135.634 199.110 1.00 93.51  ? 360 SER A CA  1 
ATOM   2631  C C   . SER A 1 360 ? 161.907 135.108 198.725 1.00 93.51  ? 360 SER A C   1 
ATOM   2632  O O   . SER A 1 360 ? 162.925 135.762 198.981 1.00 93.51  ? 360 SER A O   1 
ATOM   2633  C CB  . SER A 1 360 ? 160.065 135.013 200.427 1.00 93.51  ? 360 SER A CB  1 
ATOM   2634  O OG  . SER A 1 360 ? 159.987 133.602 200.325 1.00 93.51  ? 360 SER A OG  1 
ATOM   2635  N N   . GLU A 1 361 ? 161.959 133.922 198.114 1.00 92.82  ? 361 GLU A N   1 
ATOM   2636  C CA  . GLU A 1 361 ? 163.234 133.380 197.657 1.00 92.82  ? 361 GLU A CA  1 
ATOM   2637  C C   . GLU A 1 361 ? 163.839 134.242 196.556 1.00 92.82  ? 361 GLU A C   1 
ATOM   2638  O O   . GLU A 1 361 ? 165.054 134.471 196.536 1.00 92.82  ? 361 GLU A O   1 
ATOM   2639  C CB  . GLU A 1 361 ? 163.051 131.941 197.176 1.00 92.82  ? 361 GLU A CB  1 
ATOM   2640  C CG  . GLU A 1 361 ? 162.583 130.983 198.260 1.00 92.82  ? 361 GLU A CG  1 
ATOM   2641  C CD  . GLU A 1 361 ? 162.633 129.534 197.819 1.00 92.82  ? 361 GLU A CD  1 
ATOM   2642  O OE1 . GLU A 1 361 ? 162.946 129.281 196.638 1.00 92.82  ? 361 GLU A OE1 1 
ATOM   2643  O OE2 . GLU A 1 361 ? 162.359 128.648 198.655 1.00 92.82  ? 361 GLU A OE2 1 
ATOM   2644  N N   . GLY A 1 362 ? 163.018 134.724 195.641 1.00 89.90  ? 362 GLY A N   1 
ATOM   2645  C CA  . GLY A 1 362 ? 163.489 135.584 194.572 1.00 89.90  ? 362 GLY A CA  1 
ATOM   2646  C C   . GLY A 1 362 ? 162.588 135.488 193.361 1.00 89.90  ? 362 GLY A C   1 
ATOM   2647  O O   . GLY A 1 362 ? 161.685 134.658 193.283 1.00 89.90  ? 362 GLY A O   1 
ATOM   2648  N N   . THR A 1 363 ? 162.856 136.367 192.400 1.00 83.54  ? 363 THR A N   1 
ATOM   2649  C CA  . THR A 1 363 ? 162.081 136.409 191.170 1.00 83.54  ? 363 THR A CA  1 
ATOM   2650  C C   . THR A 1 363 ? 162.492 135.281 190.232 1.00 83.54  ? 363 THR A C   1 
ATOM   2651  O O   . THR A 1 363 ? 163.645 134.840 190.222 1.00 83.54  ? 363 THR A O   1 
ATOM   2652  C CB  . THR A 1 363 ? 162.256 137.756 190.467 1.00 83.54  ? 363 THR A CB  1 
ATOM   2653  O OG1 . THR A 1 363 ? 163.614 137.898 190.036 1.00 83.54  ? 363 THR A OG1 1 
ATOM   2654  C CG2 . THR A 1 363 ? 161.905 138.897 191.409 1.00 83.54  ? 363 THR A CG2 1 
ATOM   2655  N N   . GLY A 1 364 ? 161.531 134.817 189.439 1.00 79.17  ? 364 GLY A N   1 
ATOM   2656  C CA  . GLY A 1 364 ? 161.787 133.750 188.489 1.00 79.17  ? 364 GLY A CA  1 
ATOM   2657  C C   . GLY A 1 364 ? 160.911 133.897 187.265 1.00 79.17  ? 364 GLY A C   1 
ATOM   2658  O O   . GLY A 1 364 ? 159.921 134.635 187.264 1.00 79.17  ? 364 GLY A O   1 
ATOM   2659  N N   . GLN A 1 365 ? 161.293 133.178 186.212 1.00 72.97  ? 365 GLN A N   1 
ATOM   2660  C CA  . GLN A 1 365 ? 160.580 133.217 184.945 1.00 72.97  ? 365 GLN A CA  1 
ATOM   2661  C C   . GLN A 1 365 ? 160.452 131.800 184.404 1.00 72.97  ? 365 GLN A C   1 
ATOM   2662  O O   . GLN A 1 365 ? 161.303 130.944 184.656 1.00 72.97  ? 365 GLN A O   1 
ATOM   2663  C CB  . GLN A 1 365 ? 161.301 134.127 183.934 1.00 72.97  ? 365 GLN A CB  1 
ATOM   2664  C CG  . GLN A 1 365 ? 160.761 134.074 182.513 1.00 72.97  ? 365 GLN A CG  1 
ATOM   2665  C CD  . GLN A 1 365 ? 161.062 135.332 181.727 1.00 72.97  ? 365 GLN A CD  1 
ATOM   2666  O OE1 . GLN A 1 365 ? 161.579 136.308 182.268 1.00 72.97  ? 365 GLN A OE1 1 
ATOM   2667  N NE2 . GLN A 1 365 ? 160.739 135.315 180.439 1.00 72.97  ? 365 GLN A NE2 1 
ATOM   2668  N N   . ALA A 1 366 ? 159.374 131.558 183.665 1.00 72.06  ? 366 ALA A N   1 
ATOM   2669  C CA  . ALA A 1 366 ? 159.140 130.267 183.032 1.00 72.06  ? 366 ALA A CA  1 
ATOM   2670  C C   . ALA A 1 366 ? 158.336 130.502 181.759 1.00 72.06  ? 366 ALA A C   1 
ATOM   2671  O O   . ALA A 1 366 ? 157.986 131.637 181.423 1.00 72.06  ? 366 ALA A O   1 
ATOM   2672  C CB  . ALA A 1 366 ? 158.427 129.302 183.981 1.00 72.06  ? 366 ALA A CB  1 
ATOM   2673  N N   . ALA A 1 367 ? 158.049 129.416 181.048 1.00 69.54  ? 367 ALA A N   1 
ATOM   2674  C CA  . ALA A 1 367 ? 157.305 129.476 179.801 1.00 69.54  ? 367 ALA A CA  1 
ATOM   2675  C C   . ALA A 1 367 ? 156.215 128.416 179.799 1.00 69.54  ? 367 ALA A C   1 
ATOM   2676  O O   . ALA A 1 367 ? 156.359 127.350 180.403 1.00 69.54  ? 367 ALA A O   1 
ATOM   2677  C CB  . ALA A 1 367 ? 158.223 129.282 178.587 1.00 69.54  ? 367 ALA A CB  1 
ATOM   2678  N N   . ASP A 1 368 ? 155.119 128.723 179.112 1.00 67.39  ? 368 ASP A N   1 
ATOM   2679  C CA  . ASP A 1 368 ? 154.009 127.796 178.947 1.00 67.39  ? 368 ASP A CA  1 
ATOM   2680  C C   . ASP A 1 368 ? 154.057 127.208 177.544 1.00 67.39  ? 368 ASP A C   1 
ATOM   2681  O O   . ASP A 1 368 ? 154.090 127.948 176.556 1.00 67.39  ? 368 ASP A O   1 
ATOM   2682  C CB  . ASP A 1 368 ? 152.670 128.494 179.189 1.00 67.39  ? 368 ASP A CB  1 
ATOM   2683  C CG  . ASP A 1 368 ? 151.544 127.517 179.468 1.00 67.39  ? 368 ASP A CG  1 
ATOM   2684  O OD1 . ASP A 1 368 ? 151.339 126.590 178.657 1.00 67.39  ? 368 ASP A OD1 1 
ATOM   2685  O OD2 . ASP A 1 368 ? 150.864 127.672 180.503 1.00 67.39  ? 368 ASP A OD2 1 
ATOM   2686  N N   . LEU A 1 369 ? 154.065 125.879 177.463 1.00 67.68  ? 369 LEU A N   1 
ATOM   2687  C CA  . LEU A 1 369 ? 154.172 125.199 176.179 1.00 67.68  ? 369 LEU A CA  1 
ATOM   2688  C C   . LEU A 1 369 ? 152.822 124.939 175.529 1.00 67.68  ? 369 LEU A C   1 
ATOM   2689  O O   . LEU A 1 369 ? 152.739 124.897 174.296 1.00 67.68  ? 369 LEU A O   1 
ATOM   2690  C CB  . LEU A 1 369 ? 154.917 123.872 176.344 1.00 67.68  ? 369 LEU A CB  1 
ATOM   2691  C CG  . LEU A 1 369 ? 156.184 123.875 177.204 1.00 67.68  ? 369 LEU A CG  1 
ATOM   2692  C CD1 . LEU A 1 369 ? 156.834 122.501 177.191 1.00 67.68  ? 369 LEU A CD1 1 
ATOM   2693  C CD2 . LEU A 1 369 ? 157.164 124.936 176.728 1.00 67.68  ? 369 LEU A CD2 1 
ATOM   2694  N N   . LYS A 1 370 ? 151.764 124.766 176.324 1.00 67.13  ? 370 LYS A N   1 
ATOM   2695  C CA  . LYS A 1 370 ? 150.462 124.414 175.762 1.00 67.13  ? 370 LYS A CA  1 
ATOM   2696  C C   . LYS A 1 370 ? 149.935 125.518 174.854 1.00 67.13  ? 370 LYS A C   1 
ATOM   2697  O O   . LYS A 1 370 ? 149.596 125.273 173.689 1.00 67.13  ? 370 LYS A O   1 
ATOM   2698  C CB  . LYS A 1 370 ? 149.470 124.132 176.891 1.00 67.13  ? 370 LYS A CB  1 
ATOM   2699  C CG  . LYS A 1 370 ? 149.837 122.950 177.772 1.00 67.13  ? 370 LYS A CG  1 
ATOM   2700  C CD  . LYS A 1 370 ? 148.830 122.781 178.900 1.00 67.13  ? 370 LYS A CD  1 
ATOM   2701  C CE  . LYS A 1 370 ? 149.144 121.560 179.751 1.00 67.13  ? 370 LYS A CE  1 
ATOM   2702  N NZ  . LYS A 1 370 ? 148.129 121.356 180.822 1.00 67.13  ? 370 LYS A NZ  1 
ATOM   2703  N N   . SER A 1 371 ? 149.880 126.750 175.366 1.00 63.78  ? 371 SER A N   1 
ATOM   2704  C CA  . SER A 1 371 ? 149.354 127.862 174.580 1.00 63.78  ? 371 SER A CA  1 
ATOM   2705  C C   . SER A 1 371 ? 150.266 128.194 173.407 1.00 63.78  ? 371 SER A C   1 
ATOM   2706  O O   . SER A 1 371 ? 149.787 128.500 172.308 1.00 63.78  ? 371 SER A O   1 
ATOM   2707  C CB  . SER A 1 371 ? 149.158 129.085 175.474 1.00 63.78  ? 371 SER A CB  1 
ATOM   2708  O OG  . SER A 1 371 ? 150.321 129.342 176.242 1.00 63.78  ? 371 SER A OG  1 
ATOM   2709  N N   . THR A 1 372 ? 151.582 128.142 173.624 1.00 61.82  ? 372 THR A N   1 
ATOM   2710  C CA  . THR A 1 372 ? 152.528 128.410 172.545 1.00 61.82  ? 372 THR A CA  1 
ATOM   2711  C C   . THR A 1 372 ? 152.341 127.424 171.399 1.00 61.82  ? 372 THR A C   1 
ATOM   2712  O O   . THR A 1 372 ? 152.263 127.818 170.228 1.00 61.82  ? 372 THR A O   1 
ATOM   2713  C CB  . THR A 1 372 ? 153.960 128.344 173.078 1.00 61.82  ? 372 THR A CB  1 
ATOM   2714  O OG1 . THR A 1 372 ? 154.130 129.309 174.123 1.00 61.82  ? 372 THR A OG1 1 
ATOM   2715  C CG2 . THR A 1 372 ? 154.957 128.626 171.965 1.00 61.82  ? 372 THR A CG2 1 
ATOM   2716  N N   . GLN A 1 373 ? 152.246 126.133 171.722 1.00 60.79  ? 373 GLN A N   1 
ATOM   2717  C CA  . GLN A 1 373 ? 152.096 125.125 170.682 1.00 60.79  ? 373 GLN A CA  1 
ATOM   2718  C C   . GLN A 1 373 ? 150.728 125.216 170.019 1.00 60.79  ? 373 GLN A C   1 
ATOM   2719  O O   . GLN A 1 373 ? 150.606 124.984 168.812 1.00 60.79  ? 373 GLN A O   1 
ATOM   2720  C CB  . GLN A 1 373 ? 152.327 123.731 171.263 1.00 60.79  ? 373 GLN A CB  1 
ATOM   2721  C CG  . GLN A 1 373 ? 152.266 122.614 170.235 1.00 60.79  ? 373 GLN A CG  1 
ATOM   2722  C CD  . GLN A 1 373 ? 153.337 122.748 169.170 1.00 60.79  ? 373 GLN A CD  1 
ATOM   2723  O OE1 . GLN A 1 373 ? 153.058 123.141 168.037 1.00 60.79  ? 373 GLN A OE1 1 
ATOM   2724  N NE2 . GLN A 1 373 ? 154.573 122.426 169.530 1.00 60.79  ? 373 GLN A NE2 1 
ATOM   2725  N N   . ALA A 1 374 ? 149.688 125.564 170.781 1.00 60.33  ? 374 ALA A N   1 
ATOM   2726  C CA  . ALA A 1 374 ? 148.368 125.741 170.183 1.00 60.33  ? 374 ALA A CA  1 
ATOM   2727  C C   . ALA A 1 374 ? 148.374 126.882 169.172 1.00 60.33  ? 374 ALA A C   1 
ATOM   2728  O O   . ALA A 1 374 ? 147.846 126.747 168.060 1.00 60.33  ? 374 ALA A O   1 
ATOM   2729  C CB  . ALA A 1 374 ? 147.327 125.990 171.274 1.00 60.33  ? 374 ALA A CB  1 
ATOM   2730  N N   . ALA A 1 375 ? 148.977 128.015 169.540 1.00 58.59  ? 375 ALA A N   1 
ATOM   2731  C CA  . ALA A 1 375 ? 149.063 129.141 168.616 1.00 58.59  ? 375 ALA A CA  1 
ATOM   2732  C C   . ALA A 1 375 ? 149.896 128.788 167.390 1.00 58.59  ? 375 ALA A C   1 
ATOM   2733  O O   . ALA A 1 375 ? 149.538 129.148 166.262 1.00 58.59  ? 375 ALA A O   1 
ATOM   2734  C CB  . ALA A 1 375 ? 149.645 130.361 169.329 1.00 58.59  ? 375 ALA A CB  1 
ATOM   2735  N N   . ILE A 1 376 ? 151.009 128.078 167.591 1.00 58.26  ? 376 ILE A N   1 
ATOM   2736  C CA  . ILE A 1 376 ? 151.859 127.693 166.466 1.00 58.26  ? 376 ILE A CA  1 
ATOM   2737  C C   . ILE A 1 376 ? 151.105 126.767 165.519 1.00 58.26  ? 376 ILE A C   1 
ATOM   2738  O O   . ILE A 1 376 ? 151.189 126.907 164.292 1.00 58.26  ? 376 ILE A O   1 
ATOM   2739  C CB  . ILE A 1 376 ? 153.161 127.053 166.982 1.00 58.26  ? 376 ILE A CB  1 
ATOM   2740  C CG1 . ILE A 1 376 ? 154.161 128.139 167.383 1.00 58.26  ? 376 ILE A CG1 1 
ATOM   2741  C CG2 . ILE A 1 376 ? 153.767 126.131 165.934 1.00 58.26  ? 376 ILE A CG2 1 
ATOM   2742  C CD1 . ILE A 1 376 ? 155.359 127.618 168.140 1.00 58.26  ? 376 ILE A CD1 1 
ATOM   2743  N N   . ASP A 1 377 ? 150.355 125.810 166.069 1.00 57.80  ? 377 ASP A N   1 
ATOM   2744  C CA  . ASP A 1 377 ? 149.573 124.903 165.235 1.00 57.80  ? 377 ASP A CA  1 
ATOM   2745  C C   . ASP A 1 377 ? 148.487 125.649 164.471 1.00 57.80  ? 377 ASP A C   1 
ATOM   2746  O O   . ASP A 1 377 ? 148.249 125.372 163.290 1.00 57.80  ? 377 ASP A O   1 
ATOM   2747  C CB  . ASP A 1 377 ? 148.959 123.798 166.094 1.00 57.80  ? 377 ASP A CB  1 
ATOM   2748  C CG  . ASP A 1 377 ? 149.998 122.841 166.642 1.00 57.80  ? 377 ASP A CG  1 
ATOM   2749  O OD1 . ASP A 1 377 ? 151.043 122.655 165.984 1.00 57.80  ? 377 ASP A OD1 1 
ATOM   2750  O OD2 . ASP A 1 377 ? 149.770 122.276 167.732 1.00 57.80  ? 377 ASP A OD2 1 
ATOM   2751  N N   . GLN A 1 378 ? 147.813 126.597 165.127 1.00 54.67  ? 378 GLN A N   1 
ATOM   2752  C CA  . GLN A 1 378 ? 146.768 127.353 164.445 1.00 54.67  ? 378 GLN A CA  1 
ATOM   2753  C C   . GLN A 1 378 ? 147.327 128.307 163.399 1.00 54.67  ? 378 GLN A C   1 
ATOM   2754  O O   . GLN A 1 378 ? 146.608 128.666 162.461 1.00 54.67  ? 378 GLN A O   1 
ATOM   2755  C CB  . GLN A 1 378 ? 145.927 128.134 165.456 1.00 54.67  ? 378 GLN A CB  1 
ATOM   2756  C CG  . GLN A 1 378 ? 145.103 127.263 166.386 1.00 54.67  ? 378 GLN A CG  1 
ATOM   2757  C CD  . GLN A 1 378 ? 144.300 128.073 167.382 1.00 54.67  ? 378 GLN A CD  1 
ATOM   2758  O OE1 . GLN A 1 378 ? 144.402 129.298 167.429 1.00 54.67  ? 378 GLN A OE1 1 
ATOM   2759  N NE2 . GLN A 1 378 ? 143.498 127.391 168.189 1.00 54.67  ? 378 GLN A NE2 1 
ATOM   2760  N N   . ILE A 1 379 ? 148.583 128.722 163.532 1.00 52.78  ? 379 ILE A N   1 
ATOM   2761  C CA  . ILE A 1 379 ? 149.180 129.657 162.581 1.00 52.78  ? 379 ILE A CA  1 
ATOM   2762  C C   . ILE A 1 379 ? 149.777 128.930 161.383 1.00 52.78  ? 379 ILE A C   1 
ATOM   2763  O O   . ILE A 1 379 ? 149.602 129.353 160.237 1.00 52.78  ? 379 ILE A O   1 
ATOM   2764  C CB  . ILE A 1 379 ? 150.232 130.533 163.297 1.00 52.78  ? 379 ILE A CB  1 
ATOM   2765  C CG1 . ILE A 1 379 ? 149.551 131.692 164.026 1.00 52.78  ? 379 ILE A CG1 1 
ATOM   2766  C CG2 . ILE A 1 379 ? 151.265 131.058 162.312 1.00 52.78  ? 379 ILE A CG2 1 
ATOM   2767  C CD1 . ILE A 1 379 ? 150.505 132.585 164.779 1.00 52.78  ? 379 ILE A CD1 1 
ATOM   2768  N N   . ASN A 1 380 ? 150.480 127.826 161.622 1.00 53.84  ? 380 ASN A N   1 
ATOM   2769  C CA  . ASN A 1 380 ? 151.181 127.131 160.550 1.00 53.84  ? 380 ASN A CA  1 
ATOM   2770  C C   . ASN A 1 380 ? 150.201 126.521 159.554 1.00 53.84  ? 380 ASN A C   1 
ATOM   2771  O O   . ASN A 1 380 ? 149.192 125.921 159.934 1.00 53.84  ? 380 ASN A O   1 
ATOM   2772  C CB  . ASN A 1 380 ? 152.081 126.039 161.127 1.00 53.84  ? 380 ASN A CB  1 
ATOM   2773  C CG  . ASN A 1 380 ? 153.439 126.564 161.546 1.00 53.84  ? 380 ASN A CG  1 
ATOM   2774  O OD1 . ASN A 1 380 ? 153.594 127.747 161.848 1.00 53.84  ? 380 ASN A OD1 1 
ATOM   2775  N ND2 . ASN A 1 380 ? 154.433 125.684 161.567 1.00 53.84  ? 380 ASN A ND2 1 
ATOM   2776  N N   . GLY A 1 381 ? 150.512 126.675 158.267 1.00 50.95  ? 381 GLY A N   1 
ATOM   2777  C CA  . GLY A 1 381 ? 149.701 126.090 157.218 1.00 50.95  ? 381 GLY A CA  1 
ATOM   2778  C C   . GLY A 1 381 ? 148.346 126.729 157.024 1.00 50.95  ? 381 GLY A C   1 
ATOM   2779  O O   . GLY A 1 381 ? 147.450 126.095 156.462 1.00 50.95  ? 381 GLY A O   1 
ATOM   2780  N N   . LYS A 1 382 ? 148.171 127.974 157.469 1.00 46.56  ? 382 LYS A N   1 
ATOM   2781  C CA  . LYS A 1 382 ? 146.852 128.598 157.423 1.00 46.56  ? 382 LYS A CA  1 
ATOM   2782  C C   . LYS A 1 382 ? 146.440 128.941 155.997 1.00 46.56  ? 382 LYS A C   1 
ATOM   2783  O O   . LYS A 1 382 ? 145.257 128.852 155.650 1.00 46.56  ? 382 LYS A O   1 
ATOM   2784  C CB  . LYS A 1 382 ? 146.835 129.848 158.301 1.00 46.56  ? 382 LYS A CB  1 
ATOM   2785  C CG  . LYS A 1 382 ? 145.440 130.359 158.613 1.00 46.56  ? 382 LYS A CG  1 
ATOM   2786  C CD  . LYS A 1 382 ? 145.488 131.723 159.273 1.00 46.56  ? 382 LYS A CD  1 
ATOM   2787  C CE  . LYS A 1 382 ? 145.857 131.614 160.736 1.00 46.56  ? 382 LYS A CE  1 
ATOM   2788  N NZ  . LYS A 1 382 ? 145.850 132.946 161.388 1.00 46.56  ? 382 LYS A NZ  1 
ATOM   2789  N N   . LEU A 1 383 ? 147.398 129.338 155.156 1.00 45.72  ? 383 LEU A N   1 
ATOM   2790  C CA  . LEU A 1 383 ? 147.052 129.785 153.811 1.00 45.72  ? 383 LEU A CA  1 
ATOM   2791  C C   . LEU A 1 383 ? 146.669 128.622 152.905 1.00 45.72  ? 383 LEU A C   1 
ATOM   2792  O O   . LEU A 1 383 ? 145.936 128.814 151.929 1.00 45.72  ? 383 LEU A O   1 
ATOM   2793  C CB  . LEU A 1 383 ? 148.214 130.569 153.203 1.00 45.72  ? 383 LEU A CB  1 
ATOM   2794  C CG  . LEU A 1 383 ? 147.873 131.478 152.023 1.00 45.72  ? 383 LEU A CG  1 
ATOM   2795  C CD1 . LEU A 1 383 ? 147.061 132.671 152.496 1.00 45.72  ? 383 LEU A CD1 1 
ATOM   2796  C CD2 . LEU A 1 383 ? 149.134 131.932 151.313 1.00 45.72  ? 383 LEU A CD2 1 
ATOM   2797  N N   . ASN A 1 384 ? 147.147 127.414 153.208 1.00 48.79  ? 384 ASN A N   1 
ATOM   2798  C CA  . ASN A 1 384 ? 146.836 126.253 152.384 1.00 48.79  ? 384 ASN A CA  1 
ATOM   2799  C C   . ASN A 1 384 ? 145.403 125.769 152.556 1.00 48.79  ? 384 ASN A C   1 
ATOM   2800  O O   . ASN A 1 384 ? 144.946 124.951 151.752 1.00 48.79  ? 384 ASN A O   1 
ATOM   2801  C CB  . ASN A 1 384 ? 147.804 125.112 152.703 1.00 48.79  ? 384 ASN A CB  1 
ATOM   2802  C CG  . ASN A 1 384 ? 149.240 125.454 152.363 1.00 48.79  ? 384 ASN A CG  1 
ATOM   2803  O OD1 . ASN A 1 384 ? 150.092 125.553 153.245 1.00 48.79  ? 384 ASN A OD1 1 
ATOM   2804  N ND2 . ASN A 1 384 ? 149.516 125.637 151.077 1.00 48.79  ? 384 ASN A ND2 1 
ATOM   2805  N N   . ARG A 1 385 ? 144.689 126.244 153.577 1.00 45.73  ? 385 ARG A N   1 
ATOM   2806  C CA  . ARG A 1 385 ? 143.321 125.800 153.811 1.00 45.73  ? 385 ARG A CA  1 
ATOM   2807  C C   . ARG A 1 385 ? 142.319 126.422 152.847 1.00 45.73  ? 385 ARG A C   1 
ATOM   2808  O O   . ARG A 1 385 ? 141.214 125.890 152.698 1.00 45.73  ? 385 ARG A O   1 
ATOM   2809  C CB  . ARG A 1 385 ? 142.902 126.114 155.249 1.00 45.73  ? 385 ARG A CB  1 
ATOM   2810  C CG  . ARG A 1 385 ? 143.436 125.137 156.282 1.00 45.73  ? 385 ARG A CG  1 
ATOM   2811  C CD  . ARG A 1 385 ? 143.610 125.808 157.635 1.00 45.73  ? 385 ARG A CD  1 
ATOM   2812  N NE  . ARG A 1 385 ? 144.720 125.239 158.390 1.00 45.73  ? 385 ARG A NE  1 
ATOM   2813  C CZ  . ARG A 1 385 ? 145.333 125.849 159.395 1.00 45.73  ? 385 ARG A CZ  1 
ATOM   2814  N NH1 . ARG A 1 385 ? 144.967 127.053 159.800 1.00 45.73  ? 385 ARG A NH1 1 
ATOM   2815  N NH2 . ARG A 1 385 ? 146.338 125.234 160.011 1.00 45.73  ? 385 ARG A NH2 1 
ATOM   2816  N N   . VAL A 1 386 ? 142.671 127.525 152.193 1.00 43.83  ? 386 VAL A N   1 
ATOM   2817  C CA  . VAL A 1 386 ? 141.759 128.251 151.318 1.00 43.83  ? 386 VAL A CA  1 
ATOM   2818  C C   . VAL A 1 386 ? 142.210 128.188 149.863 1.00 43.83  ? 386 VAL A C   1 
ATOM   2819  O O   . VAL A 1 386 ? 141.468 127.727 148.994 1.00 43.83  ? 386 VAL A O   1 
ATOM   2820  C CB  . VAL A 1 386 ? 141.593 129.715 151.783 1.00 43.83  ? 386 VAL A CB  1 
ATOM   2821  C CG1 . VAL A 1 386 ? 140.922 130.542 150.700 1.00 43.83  ? 386 VAL A CG1 1 
ATOM   2822  C CG2 . VAL A 1 386 ? 140.791 129.773 153.072 1.00 43.83  ? 386 VAL A CG2 1 
ATOM   2823  N N   . ILE A 1 387 ? 143.423 128.646 149.578 1.00 46.50  ? 387 ILE A N   1 
ATOM   2824  C CA  . ILE A 1 387 ? 143.928 128.734 148.213 1.00 46.50  ? 387 ILE A CA  1 
ATOM   2825  C C   . ILE A 1 387 ? 144.639 127.436 147.857 1.00 46.50  ? 387 ILE A C   1 
ATOM   2826  O O   . ILE A 1 387 ? 145.313 126.826 148.698 1.00 46.50  ? 387 ILE A O   1 
ATOM   2827  C CB  . ILE A 1 387 ? 144.853 129.955 148.035 1.00 46.50  ? 387 ILE A CB  1 
ATOM   2828  C CG1 . ILE A 1 387 ? 145.141 130.202 146.552 1.00 46.50  ? 387 ILE A CG1 1 
ATOM   2829  C CG2 . ILE A 1 387 ? 146.145 129.792 148.822 1.00 46.50  ? 387 ILE A CG2 1 
ATOM   2830  C CD1 . ILE A 1 387 ? 145.322 131.660 146.201 1.00 46.50  ? 387 ILE A CD1 1 
ATOM   2831  N N   . GLU A 1 388 ? 144.463 126.997 146.614 1.00 52.81  ? 388 GLU A N   1 
ATOM   2832  C CA  . GLU A 1 388 ? 145.130 125.799 146.133 1.00 52.81  ? 388 GLU A CA  1 
ATOM   2833  C C   . GLU A 1 388 ? 146.618 126.070 145.928 1.00 52.81  ? 388 GLU A C   1 
ATOM   2834  O O   . GLU A 1 388 ? 147.065 127.218 145.858 1.00 52.81  ? 388 GLU A O   1 
ATOM   2835  C CB  . GLU A 1 388 ? 144.486 125.314 144.834 1.00 52.81  ? 388 GLU A CB  1 
ATOM   2836  C CG  . GLU A 1 388 ? 143.044 124.836 144.987 1.00 52.81  ? 388 GLU A CG  1 
ATOM   2837  C CD  . GLU A 1 388 ? 142.038 125.976 145.040 1.00 52.81  ? 388 GLU A CD  1 
ATOM   2838  O OE1 . GLU A 1 388 ? 142.454 127.150 144.947 1.00 52.81  ? 388 GLU A OE1 1 
ATOM   2839  O OE2 . GLU A 1 388 ? 140.827 125.695 145.174 1.00 52.81  ? 388 GLU A OE2 1 
ATOM   2840  N N   . LYS A 1 389 ? 147.391 124.988 145.832 1.00 57.60  ? 389 LYS A N   1 
ATOM   2841  C CA  . LYS A 1 389 ? 148.844 125.105 145.818 1.00 57.60  ? 389 LYS A CA  1 
ATOM   2842  C C   . LYS A 1 389 ? 149.351 125.751 144.534 1.00 57.60  ? 389 LYS A C   1 
ATOM   2843  O O   . LYS A 1 389 ? 149.916 126.849 144.569 1.00 57.60  ? 389 LYS A O   1 
ATOM   2844  C CB  . LYS A 1 389 ? 149.486 123.729 146.003 1.00 57.60  ? 389 LYS A CB  1 
ATOM   2845  C CG  . LYS A 1 389 ? 150.867 123.767 146.637 1.00 57.60  ? 389 LYS A CG  1 
ATOM   2846  C CD  . LYS A 1 389 ? 151.329 122.374 147.027 1.00 57.60  ? 389 LYS A CD  1 
ATOM   2847  C CE  . LYS A 1 389 ? 152.664 122.417 147.752 1.00 57.60  ? 389 LYS A CE  1 
ATOM   2848  N NZ  . LYS A 1 389 ? 153.095 121.063 148.196 1.00 57.60  ? 389 LYS A NZ  1 
ATOM   2849  N N   . THR A 1 390 ? 149.145 125.088 143.397 1.00 51.90  ? 390 THR A N   1 
ATOM   2850  C CA  . THR A 1 390 ? 149.579 125.601 142.105 1.00 51.90  ? 390 THR A CA  1 
ATOM   2851  C C   . THR A 1 390 ? 148.546 125.246 141.048 1.00 51.90  ? 390 THR A C   1 
ATOM   2852  O O   . THR A 1 390 ? 147.736 124.332 141.220 1.00 51.90  ? 390 THR A O   1 
ATOM   2853  C CB  . THR A 1 390 ? 150.949 125.044 141.673 1.00 51.90  ? 390 THR A CB  1 
ATOM   2854  O OG1 . THR A 1 390 ? 150.873 123.618 141.545 1.00 51.90  ? 390 THR A OG1 1 
ATOM   2855  C CG2 . THR A 1 390 ? 152.049 125.416 142.660 1.00 51.90  ? 390 THR A CG2 1 
ATOM   2856  N N   . ASN A 1 391 ? 148.584 125.989 139.945 1.00 43.13  ? 391 ASN A N   1 
ATOM   2857  C CA  . ASN A 1 391 ? 147.795 125.690 138.758 1.00 43.13  ? 391 ASN A CA  1 
ATOM   2858  C C   . ASN A 1 391 ? 148.743 125.484 137.585 1.00 43.13  ? 391 ASN A C   1 
ATOM   2859  O O   . ASN A 1 391 ? 149.629 126.311 137.345 1.00 43.13  ? 391 ASN A O   1 
ATOM   2860  C CB  . ASN A 1 391 ? 146.784 126.804 138.465 1.00 43.13  ? 391 ASN A CB  1 
ATOM   2861  C CG  . ASN A 1 391 ? 147.402 128.192 138.510 1.00 43.13  ? 391 ASN A CG  1 
ATOM   2862  O OD1 . ASN A 1 391 ? 148.593 128.351 138.766 1.00 43.13  ? 391 ASN A OD1 1 
ATOM   2863  N ND2 . ASN A 1 391 ? 146.586 129.207 138.254 1.00 43.13  ? 391 ASN A ND2 1 
ATOM   2864  N N   . GLU A 1 392 ? 148.568 124.378 136.868 1.00 36.69  ? 392 GLU A N   1 
ATOM   2865  C CA  . GLU A 1 392 ? 149.405 124.046 135.721 1.00 36.69  ? 392 GLU A CA  1 
ATOM   2866  C C   . GLU A 1 392 ? 148.664 124.439 134.449 1.00 36.69  ? 392 GLU A C   1 
ATOM   2867  O O   . GLU A 1 392 ? 147.689 123.787 134.062 1.00 36.69  ? 392 GLU A O   1 
ATOM   2868  C CB  . GLU A 1 392 ? 149.761 122.562 135.716 1.00 36.69  ? 392 GLU A CB  1 
ATOM   2869  C CG  . GLU A 1 392 ? 151.102 122.253 136.355 1.00 36.69  ? 392 GLU A CG  1 
ATOM   2870  C CD  . GLU A 1 392 ? 151.612 120.869 136.009 1.00 36.69  ? 392 GLU A CD  1 
ATOM   2871  O OE1 . GLU A 1 392 ? 150.865 119.890 136.214 1.00 36.69  ? 392 GLU A OE1 1 
ATOM   2872  O OE2 . GLU A 1 392 ? 152.763 120.760 135.538 1.00 36.69  ? 392 GLU A OE2 1 
ATOM   2873  N N   . LYS A 1 393 ? 149.127 125.506 133.804 1.00 31.74  ? 393 LYS A N   1 
ATOM   2874  C CA  . LYS A 1 393 ? 148.576 125.976 132.542 1.00 31.74  ? 393 LYS A CA  1 
ATOM   2875  C C   . LYS A 1 393 ? 149.669 125.919 131.488 1.00 31.74  ? 393 LYS A C   1 
ATOM   2876  O O   . LYS A 1 393 ? 150.794 126.367 131.733 1.00 31.74  ? 393 LYS A O   1 
ATOM   2877  C CB  . LYS A 1 393 ? 148.029 127.399 132.674 1.00 31.74  ? 393 LYS A CB  1 
ATOM   2878  C CG  . LYS A 1 393 ? 147.232 127.638 133.943 1.00 31.74  ? 393 LYS A CG  1 
ATOM   2879  C CD  . LYS A 1 393 ? 145.762 127.326 133.736 1.00 31.74  ? 393 LYS A CD  1 
ATOM   2880  C CE  . LYS A 1 393 ? 145.013 127.296 135.056 1.00 31.74  ? 393 LYS A CE  1 
ATOM   2881  N NZ  . LYS A 1 393 ? 143.755 126.509 134.959 1.00 31.74  ? 393 LYS A NZ  1 
ATOM   2882  N N   . PHE A 1 394 ? 149.343 125.364 130.320 1.00 30.21  ? 394 PHE A N   1 
ATOM   2883  C CA  . PHE A 1 394 ? 150.345 125.114 129.291 1.00 30.21  ? 394 PHE A CA  1 
ATOM   2884  C C   . PHE A 1 394 ? 150.119 125.947 128.037 1.00 30.21  ? 394 PHE A C   1 
ATOM   2885  O O   . PHE A 1 394 ? 151.009 126.706 127.645 1.00 30.21  ? 394 PHE A O   1 
ATOM   2886  C CB  . PHE A 1 394 ? 150.369 123.617 128.967 1.00 30.21  ? 394 PHE A CB  1 
ATOM   2887  C CG  . PHE A 1 394 ? 150.638 122.752 130.164 1.00 30.21  ? 394 PHE A CG  1 
ATOM   2888  C CD1 . PHE A 1 394 ? 151.868 122.791 130.798 1.00 30.21  ? 394 PHE A CD1 1 
ATOM   2889  C CD2 . PHE A 1 394 ? 149.656 121.917 130.669 1.00 30.21  ? 394 PHE A CD2 1 
ATOM   2890  C CE1 . PHE A 1 394 ? 152.119 122.005 131.901 1.00 30.21  ? 394 PHE A CE1 1 
ATOM   2891  C CE2 . PHE A 1 394 ? 149.902 121.128 131.774 1.00 30.21  ? 394 PHE A CE2 1 
ATOM   2892  C CZ  . PHE A 1 394 ? 151.135 121.172 132.391 1.00 30.21  ? 394 PHE A CZ  1 
ATOM   2893  N N   . HIS A 1 395 ? 148.957 125.846 127.399 1.00 27.39  ? 395 HIS A N   1 
ATOM   2894  C CA  . HIS A 1 395 ? 148.646 126.634 126.214 1.00 27.39  ? 395 HIS A CA  1 
ATOM   2895  C C   . HIS A 1 395 ? 147.490 127.568 126.532 1.00 27.39  ? 395 HIS A C   1 
ATOM   2896  O O   . HIS A 1 395 ? 146.462 127.132 127.061 1.00 27.39  ? 395 HIS A O   1 
ATOM   2897  C CB  . HIS A 1 395 ? 148.299 125.742 125.021 1.00 27.39  ? 395 HIS A CB  1 
ATOM   2898  C CG  . HIS A 1 395 ? 148.346 126.453 123.704 1.00 27.39  ? 395 HIS A CG  1 
ATOM   2899  N ND1 . HIS A 1 395 ? 149.508 126.978 123.183 1.00 27.39  ? 395 HIS A ND1 1 
ATOM   2900  C CD2 . HIS A 1 395 ? 147.372 126.733 122.805 1.00 27.39  ? 395 HIS A CD2 1 
ATOM   2901  C CE1 . HIS A 1 395 ? 149.250 127.547 122.020 1.00 27.39  ? 395 HIS A CE1 1 
ATOM   2902  N NE2 . HIS A 1 395 ? 147.961 127.413 121.768 1.00 27.39  ? 395 HIS A NE2 1 
ATOM   2903  N N   . GLN A 1 396 ? 147.660 128.847 126.208 1.00 27.54  ? 396 GLN A N   1 
ATOM   2904  C CA  . GLN A 1 396 ? 146.676 129.871 126.528 1.00 27.54  ? 396 GLN A CA  1 
ATOM   2905  C C   . GLN A 1 396 ? 146.571 130.820 125.340 1.00 27.54  ? 396 GLN A C   1 
ATOM   2906  O O   . GLN A 1 396 ? 147.035 130.521 124.236 1.00 27.54  ? 396 GLN A O   1 
ATOM   2907  C CB  . GLN A 1 396 ? 147.056 130.599 127.825 1.00 27.54  ? 396 GLN A CB  1 
ATOM   2908  C CG  . GLN A 1 396 ? 146.954 129.736 129.072 1.00 27.54  ? 396 GLN A CG  1 
ATOM   2909  C CD  . GLN A 1 396 ? 147.938 130.145 130.147 1.00 27.54  ? 396 GLN A CD  1 
ATOM   2910  O OE1 . GLN A 1 396 ? 147.691 131.079 130.908 1.00 27.54  ? 396 GLN A OE1 1 
ATOM   2911  N NE2 . GLN A 1 396 ? 149.064 129.446 130.213 1.00 27.54  ? 396 GLN A NE2 1 
ATOM   2912  N N   . ILE A 1 397 ? 145.948 131.974 125.570 1.00 24.78  ? 397 ILE A N   1 
ATOM   2913  C CA  . ILE A 1 397 ? 145.766 132.983 124.533 1.00 24.78  ? 397 ILE A CA  1 
ATOM   2914  C C   . ILE A 1 397 ? 147.002 133.868 124.457 1.00 24.78  ? 397 ILE A C   1 
ATOM   2915  O O   . ILE A 1 397 ? 147.840 133.863 125.365 1.00 24.78  ? 397 ILE A O   1 
ATOM   2916  C CB  . ILE A 1 397 ? 144.504 133.824 124.796 1.00 24.78  ? 397 ILE A CB  1 
ATOM   2917  C CG1 . ILE A 1 397 ? 144.603 134.512 126.158 1.00 24.78  ? 397 ILE A CG1 1 
ATOM   2918  C CG2 . ILE A 1 397 ? 143.264 132.955 124.721 1.00 24.78  ? 397 ILE A CG2 1 
ATOM   2919  C CD1 . ILE A 1 397 ? 143.666 135.684 126.325 1.00 24.78  ? 397 ILE A CD1 1 
ATOM   2920  N N   . GLU A 1 398 ? 147.128 134.625 123.371 1.00 27.19  ? 398 GLU A N   1 
ATOM   2921  C CA  . GLU A 1 398 ? 148.196 135.607 123.250 1.00 27.19  ? 398 GLU A CA  1 
ATOM   2922  C C   . GLU A 1 398 ? 147.847 136.854 124.050 1.00 27.19  ? 398 GLU A C   1 
ATOM   2923  O O   . GLU A 1 398 ? 146.687 137.271 124.102 1.00 27.19  ? 398 GLU A O   1 
ATOM   2924  C CB  . GLU A 1 398 ? 148.429 135.970 121.784 1.00 27.19  ? 398 GLU A CB  1 
ATOM   2925  C CG  . GLU A 1 398 ? 148.955 134.828 120.932 1.00 27.19  ? 398 GLU A CG  1 
ATOM   2926  C CD  . GLU A 1 398 ? 150.306 134.323 121.398 1.00 27.19  ? 398 GLU A CD  1 
ATOM   2927  O OE1 . GLU A 1 398 ? 151.229 135.148 121.550 1.00 27.19  ? 398 GLU A OE1 1 
ATOM   2928  O OE2 . GLU A 1 398 ? 150.445 133.101 121.609 1.00 27.19  ? 398 GLU A OE2 1 
ATOM   2929  N N   . LYS A 1 399 ? 148.861 137.453 124.674 1.00 25.55  ? 399 LYS A N   1 
ATOM   2930  C CA  . LYS A 1 399 ? 148.647 138.600 125.543 1.00 25.55  ? 399 LYS A CA  1 
ATOM   2931  C C   . LYS A 1 399 ? 149.458 139.828 125.156 1.00 25.55  ? 399 LYS A C   1 
ATOM   2932  O O   . LYS A 1 399 ? 149.326 140.865 125.813 1.00 25.55  ? 399 LYS A O   1 
ATOM   2933  C CB  . LYS A 1 399 ? 148.948 138.222 127.001 1.00 25.55  ? 399 LYS A CB  1 
ATOM   2934  C CG  . LYS A 1 399 ? 147.943 137.240 127.577 1.00 25.55  ? 399 LYS A CG  1 
ATOM   2935  C CD  . LYS A 1 399 ? 148.493 136.492 128.771 1.00 25.55  ? 399 LYS A CD  1 
ATOM   2936  C CE  . LYS A 1 399 ? 147.602 135.313 129.120 1.00 25.55  ? 399 LYS A CE  1 
ATOM   2937  N NZ  . LYS A 1 399 ? 148.031 134.634 130.369 1.00 25.55  ? 399 LYS A NZ  1 
ATOM   2938  N N   . GLU A 1 400 ? 150.286 139.747 124.118 1.00 28.55  ? 400 GLU A N   1 
ATOM   2939  C CA  . GLU A 1 400 ? 150.987 140.903 123.580 1.00 28.55  ? 400 GLU A CA  1 
ATOM   2940  C C   . GLU A 1 400 ? 150.881 140.883 122.064 1.00 28.55  ? 400 GLU A C   1 
ATOM   2941  O O   . GLU A 1 400 ? 151.009 139.827 121.438 1.00 28.55  ? 400 GLU A O   1 
ATOM   2942  C CB  . GLU A 1 400 ? 152.458 140.924 124.008 1.00 28.55  ? 400 GLU A CB  1 
ATOM   2943  C CG  . GLU A 1 400 ? 152.680 141.422 125.424 1.00 28.55  ? 400 GLU A CG  1 
ATOM   2944  C CD  . GLU A 1 400 ? 154.143 141.666 125.732 1.00 28.55  ? 400 GLU A CD  1 
ATOM   2945  O OE1 . GLU A 1 400 ? 154.869 142.135 124.831 1.00 28.55  ? 400 GLU A OE1 1 
ATOM   2946  O OE2 . GLU A 1 400 ? 154.567 141.392 126.873 1.00 28.55  ? 400 GLU A OE2 1 
ATOM   2947  N N   . PHE A 1 401 ? 150.646 142.053 121.477 1.00 28.99  ? 401 PHE A N   1 
ATOM   2948  C CA  . PHE A 1 401 ? 150.418 142.177 120.046 1.00 28.99  ? 401 PHE A CA  1 
ATOM   2949  C C   . PHE A 1 401 ? 151.289 143.287 119.478 1.00 28.99  ? 401 PHE A C   1 
ATOM   2950  O O   . PHE A 1 401 ? 151.530 144.306 120.130 1.00 28.99  ? 401 PHE A O   1 
ATOM   2951  C CB  . PHE A 1 401 ? 148.940 142.461 119.740 1.00 28.99  ? 401 PHE A CB  1 
ATOM   2952  C CG  . PHE A 1 401 ? 147.982 141.565 120.476 1.00 28.99  ? 401 PHE A CG  1 
ATOM   2953  C CD1 . PHE A 1 401 ? 147.570 140.365 119.922 1.00 28.99  ? 401 PHE A CD1 1 
ATOM   2954  C CD2 . PHE A 1 401 ? 147.492 141.924 121.721 1.00 28.99  ? 401 PHE A CD2 1 
ATOM   2955  C CE1 . PHE A 1 401 ? 146.690 139.541 120.596 1.00 28.99  ? 401 PHE A CE1 1 
ATOM   2956  C CE2 . PHE A 1 401 ? 146.613 141.103 122.399 1.00 28.99  ? 401 PHE A CE2 1 
ATOM   2957  C CZ  . PHE A 1 401 ? 146.211 139.911 121.835 1.00 28.99  ? 401 PHE A CZ  1 
ATOM   2958  N N   . SER A 1 402 ? 151.760 143.078 118.248 1.00 33.78  ? 402 SER A N   1 
ATOM   2959  C CA  . SER A 1 402 ? 152.589 144.053 117.555 1.00 33.78  ? 402 SER A CA  1 
ATOM   2960  C C   . SER A 1 402 ? 151.865 144.768 116.424 1.00 33.78  ? 402 SER A C   1 
ATOM   2961  O O   . SER A 1 402 ? 152.407 145.735 115.879 1.00 33.78  ? 402 SER A O   1 
ATOM   2962  C CB  . SER A 1 402 ? 153.851 143.378 116.999 1.00 33.78  ? 402 SER A CB  1 
ATOM   2963  O OG  . SER A 1 402 ? 153.524 142.431 115.997 1.00 33.78  ? 402 SER A OG  1 
ATOM   2964  N N   . GLU A 1 403 ? 150.666 144.323 116.060 1.00 37.17  ? 403 GLU A N   1 
ATOM   2965  C CA  . GLU A 1 403 ? 149.882 144.930 114.996 1.00 37.17  ? 403 GLU A CA  1 
ATOM   2966  C C   . GLU A 1 403 ? 148.461 145.149 115.493 1.00 37.17  ? 403 GLU A C   1 
ATOM   2967  O O   . GLU A 1 403 ? 147.946 144.375 116.304 1.00 37.17  ? 403 GLU A O   1 
ATOM   2968  C CB  . GLU A 1 403 ? 149.881 144.044 113.737 1.00 37.17  ? 403 GLU A CB  1 
ATOM   2969  C CG  . GLU A 1 403 ? 149.121 144.607 112.542 1.00 37.17  ? 403 GLU A CG  1 
ATOM   2970  C CD  . GLU A 1 403 ? 149.741 145.876 111.986 1.00 37.17  ? 403 GLU A CD  1 
ATOM   2971  O OE1 . GLU A 1 403 ? 150.962 146.073 112.159 1.00 37.17  ? 403 GLU A OE1 1 
ATOM   2972  O OE2 . GLU A 1 403 ? 149.005 146.675 111.370 1.00 37.17  ? 403 GLU A OE2 1 
ATOM   2973  N N   . VAL A 1 404 ? 147.831 146.216 115.010 1.00 36.06  ? 404 VAL A N   1 
ATOM   2974  C CA  . VAL A 1 404 ? 146.447 146.503 115.371 1.00 36.06  ? 404 VAL A CA  1 
ATOM   2975  C C   . VAL A 1 404 ? 145.520 145.713 114.455 1.00 36.06  ? 404 VAL A C   1 
ATOM   2976  O O   . VAL A 1 404 ? 145.728 145.651 113.236 1.00 36.06  ? 404 VAL A O   1 
ATOM   2977  C CB  . VAL A 1 404 ? 146.166 148.015 115.316 1.00 36.06  ? 404 VAL A CB  1 
ATOM   2978  C CG1 . VAL A 1 404 ? 147.198 148.770 116.136 1.00 36.06  ? 404 VAL A CG1 1 
ATOM   2979  C CG2 . VAL A 1 404 ? 146.170 148.532 113.889 1.00 36.06  ? 404 VAL A CG2 1 
ATOM   2980  N N   . GLU A 1 405 ? 144.529 145.062 115.044 1.00 33.61  ? 405 GLU A N   1 
ATOM   2981  C CA  . GLU A 1 405 ? 143.620 144.220 114.274 1.00 33.61  ? 405 GLU A CA  1 
ATOM   2982  C C   . GLU A 1 405 ? 142.156 144.574 114.472 1.00 33.61  ? 405 GLU A C   1 
ATOM   2983  O O   . GLU A 1 405 ? 141.395 144.571 113.502 1.00 33.61  ? 405 GLU A O   1 
ATOM   2984  C CB  . GLU A 1 405 ? 143.853 142.746 114.631 1.00 33.61  ? 405 GLU A CB  1 
ATOM   2985  C CG  . GLU A 1 405 ? 145.278 142.278 114.397 1.00 33.61  ? 405 GLU A CG  1 
ATOM   2986  C CD  . GLU A 1 405 ? 145.480 140.823 114.753 1.00 33.61  ? 405 GLU A CD  1 
ATOM   2987  O OE1 . GLU A 1 405 ? 144.945 139.955 114.033 1.00 33.61  ? 405 GLU A OE1 1 
ATOM   2988  O OE2 . GLU A 1 405 ? 146.176 140.546 115.752 1.00 33.61  ? 405 GLU A OE2 1 
ATOM   2989  N N   . GLY A 1 406 ? 141.739 144.882 115.698 1.00 29.13  ? 406 GLY A N   1 
ATOM   2990  C CA  . GLY A 1 406 ? 140.364 145.273 115.934 1.00 29.13  ? 406 GLY A CA  1 
ATOM   2991  C C   . GLY A 1 406 ? 139.615 144.450 116.962 1.00 29.13  ? 406 GLY A C   1 
ATOM   2992  O O   . GLY A 1 406 ? 139.963 144.448 118.145 1.00 29.13  ? 406 GLY A O   1 
ATOM   2993  N N   . ARG A 1 407 ? 138.583 143.736 116.506 1.00 28.04  ? 407 ARG A N   1 
ATOM   2994  C CA  . ARG A 1 407 ? 137.586 143.164 117.409 1.00 28.04  ? 407 ARG A CA  1 
ATOM   2995  C C   . ARG A 1 407 ? 138.172 142.062 118.292 1.00 28.04  ? 407 ARG A C   1 
ATOM   2996  O O   . ARG A 1 407 ? 138.009 142.082 119.520 1.00 28.04  ? 407 ARG A O   1 
ATOM   2997  C CB  . ARG A 1 407 ? 136.415 142.632 116.583 1.00 28.04  ? 407 ARG A CB  1 
ATOM   2998  C CG  . ARG A 1 407 ? 135.048 142.828 117.199 1.00 28.04  ? 407 ARG A CG  1 
ATOM   2999  C CD  . ARG A 1 407 ? 133.967 142.378 116.234 1.00 28.04  ? 407 ARG A CD  1 
ATOM   3000  N NE  . ARG A 1 407 ? 132.722 142.044 116.912 1.00 28.04  ? 407 ARG A NE  1 
ATOM   3001  C CZ  . ARG A 1 407 ? 131.564 141.851 116.295 1.00 28.04  ? 407 ARG A CZ  1 
ATOM   3002  N NH1 . ARG A 1 407 ? 131.456 141.960 114.982 1.00 28.04  ? 407 ARG A NH1 1 
ATOM   3003  N NH2 . ARG A 1 407 ? 130.490 141.540 117.014 1.00 28.04  ? 407 ARG A NH2 1 
ATOM   3004  N N   . ILE A 1 408 ? 138.854 141.089 117.684 1.00 27.43  ? 408 ILE A N   1 
ATOM   3005  C CA  . ILE A 1 408 ? 139.331 139.929 118.435 1.00 27.43  ? 408 ILE A CA  1 
ATOM   3006  C C   . ILE A 1 408 ? 140.409 140.337 119.431 1.00 27.43  ? 408 ILE A C   1 
ATOM   3007  O O   . ILE A 1 408 ? 140.446 139.845 120.567 1.00 27.43  ? 408 ILE A O   1 
ATOM   3008  C CB  . ILE A 1 408 ? 139.834 138.840 117.471 1.00 27.43  ? 408 ILE A CB  1 
ATOM   3009  C CG1 . ILE A 1 408 ? 138.845 138.644 116.322 1.00 27.43  ? 408 ILE A CG1 1 
ATOM   3010  C CG2 . ILE A 1 408 ? 140.047 137.532 118.211 1.00 27.43  ? 408 ILE A CG2 1 
ATOM   3011  C CD1 . ILE A 1 408 ? 137.496 138.121 116.756 1.00 27.43  ? 408 ILE A CD1 1 
ATOM   3012  N N   . GLN A 1 409 ? 141.307 141.233 119.019 1.00 27.63  ? 409 GLN A N   1 
ATOM   3013  C CA  . GLN A 1 409 ? 142.348 141.712 119.920 1.00 27.63  ? 409 GLN A CA  1 
ATOM   3014  C C   . GLN A 1 409 ? 141.747 142.448 121.110 1.00 27.63  ? 409 GLN A C   1 
ATOM   3015  O O   . GLN A 1 409 ? 142.196 142.275 122.252 1.00 27.63  ? 409 GLN A O   1 
ATOM   3016  C CB  . GLN A 1 409 ? 143.314 142.613 119.153 1.00 27.63  ? 409 GLN A CB  1 
ATOM   3017  C CG  . GLN A 1 409 ? 144.629 142.857 119.853 1.00 27.63  ? 409 GLN A CG  1 
ATOM   3018  C CD  . GLN A 1 409 ? 145.566 143.713 119.033 1.00 27.63  ? 409 GLN A CD  1 
ATOM   3019  O OE1 . GLN A 1 409 ? 145.972 144.792 119.460 1.00 27.63  ? 409 GLN A OE1 1 
ATOM   3020  N NE2 . GLN A 1 409 ? 145.918 143.235 117.847 1.00 27.63  ? 409 GLN A NE2 1 
ATOM   3021  N N   . ASP A 1 410 ? 140.724 143.269 120.861 1.00 26.17  ? 410 ASP A N   1 
ATOM   3022  C CA  . ASP A 1 410 ? 140.042 143.962 121.947 1.00 26.17  ? 410 ASP A CA  1 
ATOM   3023  C C   . ASP A 1 410 ? 139.401 142.976 122.913 1.00 26.17  ? 410 ASP A C   1 
ATOM   3024  O O   . ASP A 1 410 ? 139.485 143.150 124.135 1.00 26.17  ? 410 ASP A O   1 
ATOM   3025  C CB  . ASP A 1 410 ? 138.987 144.913 121.383 1.00 26.17  ? 410 ASP A CB  1 
ATOM   3026  C CG  . ASP A 1 410 ? 139.592 146.063 120.610 1.00 26.17  ? 410 ASP A CG  1 
ATOM   3027  O OD1 . ASP A 1 410 ? 140.833 146.206 120.629 1.00 26.17  ? 410 ASP A OD1 1 
ATOM   3028  O OD2 . ASP A 1 410 ? 138.828 146.822 119.979 1.00 26.17  ? 410 ASP A OD2 1 
ATOM   3029  N N   . LEU A 1 411 ? 138.757 141.933 122.384 1.00 24.30  ? 411 LEU A N   1 
ATOM   3030  C CA  . LEU A 1 411 ? 138.135 140.938 123.254 1.00 24.30  ? 411 LEU A CA  1 
ATOM   3031  C C   . LEU A 1 411 ? 139.174 140.223 124.112 1.00 24.30  ? 411 LEU A C   1 
ATOM   3032  O O   . LEU A 1 411 ? 138.962 140.014 125.315 1.00 24.30  ? 411 LEU A O   1 
ATOM   3033  C CB  . LEU A 1 411 ? 137.342 139.936 122.415 1.00 24.30  ? 411 LEU A CB  1 
ATOM   3034  C CG  . LEU A 1 411 ? 136.331 139.055 123.151 1.00 24.30  ? 411 LEU A CG  1 
ATOM   3035  C CD1 . LEU A 1 411 ? 135.466 139.883 124.085 1.00 24.30  ? 411 LEU A CD1 1 
ATOM   3036  C CD2 . LEU A 1 411 ? 135.473 138.293 122.159 1.00 24.30  ? 411 LEU A CD2 1 
ATOM   3037  N N   . GLU A 1 412 ? 140.305 139.843 123.511 1.00 25.08  ? 412 GLU A N   1 
ATOM   3038  C CA  . GLU A 1 412 ? 141.350 139.157 124.267 1.00 25.08  ? 412 GLU A CA  1 
ATOM   3039  C C   . GLU A 1 412 ? 141.913 140.048 125.370 1.00 25.08  ? 412 GLU A C   1 
ATOM   3040  O O   . GLU A 1 412 ? 142.098 139.602 126.515 1.00 25.08  ? 412 GLU A O   1 
ATOM   3041  C CB  . GLU A 1 412 ? 142.459 138.705 123.319 1.00 25.08  ? 412 GLU A CB  1 
ATOM   3042  C CG  . GLU A 1 412 ? 142.066 137.540 122.428 1.00 25.08  ? 412 GLU A CG  1 
ATOM   3043  C CD  . GLU A 1 412 ? 142.827 137.514 121.119 1.00 25.08  ? 412 GLU A CD  1 
ATOM   3044  O OE1 . GLU A 1 412 ? 143.449 138.538 120.769 1.00 25.08  ? 412 GLU A OE1 1 
ATOM   3045  O OE2 . GLU A 1 412 ? 142.800 136.471 120.435 1.00 25.08  ? 412 GLU A OE2 1 
ATOM   3046  N N   . LYS A 1 413 ? 142.181 141.316 125.046 1.00 24.09  ? 413 LYS A N   1 
ATOM   3047  C CA  . LYS A 1 413 ? 142.688 142.248 126.047 1.00 24.09  ? 413 LYS A CA  1 
ATOM   3048  C C   . LYS A 1 413 ? 141.686 142.437 127.179 1.00 24.09  ? 413 LYS A C   1 
ATOM   3049  O O   . LYS A 1 413 ? 142.066 142.483 128.356 1.00 24.09  ? 413 LYS A O   1 
ATOM   3050  C CB  . LYS A 1 413 ? 143.016 143.586 125.387 1.00 24.09  ? 413 LYS A CB  1 
ATOM   3051  C CG  . LYS A 1 413 ? 144.310 143.585 124.596 1.00 24.09  ? 413 LYS A CG  1 
ATOM   3052  C CD  . LYS A 1 413 ? 144.424 144.824 123.730 1.00 24.09  ? 413 LYS A CD  1 
ATOM   3053  C CE  . LYS A 1 413 ? 145.846 145.024 123.240 1.00 24.09  ? 413 LYS A CE  1 
ATOM   3054  N NZ  . LYS A 1 413 ? 146.067 146.402 122.725 1.00 24.09  ? 413 LYS A NZ  1 
ATOM   3055  N N   . TYR A 1 414 ? 140.399 142.545 126.838 1.00 22.77  ? 414 TYR A N   1 
ATOM   3056  C CA  . TYR A 1 414 ? 139.363 142.702 127.853 1.00 22.77  ? 414 TYR A CA  1 
ATOM   3057  C C   . TYR A 1 414 ? 139.321 141.503 128.792 1.00 22.77  ? 414 TYR A C   1 
ATOM   3058  O O   . TYR A 1 414 ? 139.233 141.664 130.018 1.00 22.77  ? 414 TYR A O   1 
ATOM   3059  C CB  . TYR A 1 414 ? 138.010 142.899 127.169 1.00 22.77  ? 414 TYR A CB  1 
ATOM   3060  C CG  . TYR A 1 414 ? 136.910 143.396 128.075 1.00 22.77  ? 414 TYR A CG  1 
ATOM   3061  C CD1 . TYR A 1 414 ? 136.865 144.720 128.480 1.00 22.77  ? 414 TYR A CD1 1 
ATOM   3062  C CD2 . TYR A 1 414 ? 135.911 142.542 128.516 1.00 22.77  ? 414 TYR A CD2 1 
ATOM   3063  C CE1 . TYR A 1 414 ? 135.862 145.179 129.304 1.00 22.77  ? 414 TYR A CE1 1 
ATOM   3064  C CE2 . TYR A 1 414 ? 134.903 142.992 129.340 1.00 22.77  ? 414 TYR A CE2 1 
ATOM   3065  C CZ  . TYR A 1 414 ? 134.884 144.311 129.732 1.00 22.77  ? 414 TYR A CZ  1 
ATOM   3066  O OH  . TYR A 1 414 ? 133.880 144.765 130.554 1.00 22.77  ? 414 TYR A OH  1 
ATOM   3067  N N   . VAL A 1 415 ? 139.387 140.291 128.234 1.00 22.78  ? 415 VAL A N   1 
ATOM   3068  C CA  . VAL A 1 415 ? 139.339 139.086 129.060 1.00 22.78  ? 415 VAL A CA  1 
ATOM   3069  C C   . VAL A 1 415 ? 140.524 139.050 130.018 1.00 22.78  ? 415 VAL A C   1 
ATOM   3070  O O   . VAL A 1 415 ? 140.372 138.781 131.222 1.00 22.78  ? 415 VAL A O   1 
ATOM   3071  C CB  . VAL A 1 415 ? 139.292 137.830 128.172 1.00 22.78  ? 415 VAL A CB  1 
ATOM   3072  C CG1 . VAL A 1 415 ? 139.476 136.576 129.009 1.00 22.78  ? 415 VAL A CG1 1 
ATOM   3073  C CG2 . VAL A 1 415 ? 137.985 137.770 127.404 1.00 22.78  ? 415 VAL A CG2 1 
ATOM   3074  N N   . GLU A 1 416 ? 141.724 139.330 129.499 1.00 23.81  ? 416 GLU A N   1 
ATOM   3075  C CA  . GLU A 1 416 ? 142.911 139.291 130.350 1.00 23.81  ? 416 GLU A CA  1 
ATOM   3076  C C   . GLU A 1 416 ? 142.833 140.332 131.463 1.00 23.81  ? 416 GLU A C   1 
ATOM   3077  O O   . GLU A 1 416 ? 143.167 140.043 132.622 1.00 23.81  ? 416 GLU A O   1 
ATOM   3078  C CB  . GLU A 1 416 ? 144.169 139.491 129.505 1.00 23.81  ? 416 GLU A CB  1 
ATOM   3079  C CG  . GLU A 1 416 ? 145.480 139.199 130.230 1.00 23.81  ? 416 GLU A CG  1 
ATOM   3080  C CD  . GLU A 1 416 ? 145.509 137.838 130.908 1.00 23.81  ? 416 GLU A CD  1 
ATOM   3081  O OE1 . GLU A 1 416 ? 144.840 136.902 130.422 1.00 23.81  ? 416 GLU A OE1 1 
ATOM   3082  O OE2 . GLU A 1 416 ? 146.206 137.703 131.935 1.00 23.81  ? 416 GLU A OE2 1 
ATOM   3083  N N   . ASP A 1 417 ? 142.385 141.547 131.133 1.00 24.92  ? 417 ASP A N   1 
ATOM   3084  C CA  . ASP A 1 417 ? 142.286 142.598 132.141 1.00 24.92  ? 417 ASP A CA  1 
ATOM   3085  C C   . ASP A 1 417 ? 141.283 142.233 133.230 1.00 24.92  ? 417 ASP A C   1 
ATOM   3086  O O   . ASP A 1 417 ? 141.537 142.457 134.423 1.00 24.92  ? 417 ASP A O   1 
ATOM   3087  C CB  . ASP A 1 417 ? 141.902 143.918 131.474 1.00 24.92  ? 417 ASP A CB  1 
ATOM   3088  C CG  . ASP A 1 417 ? 142.431 145.123 132.219 1.00 24.92  ? 417 ASP A CG  1 
ATOM   3089  O OD1 . ASP A 1 417 ? 143.358 144.956 133.038 1.00 24.92  ? 417 ASP A OD1 1 
ATOM   3090  O OD2 . ASP A 1 417 ? 141.922 146.238 131.983 1.00 24.92  ? 417 ASP A OD2 1 
ATOM   3091  N N   . THR A 1 418 ? 140.136 141.668 132.839 1.00 22.34  ? 418 THR A N   1 
ATOM   3092  C CA  . THR A 1 418 ? 139.136 141.262 133.822 1.00 22.34  ? 418 THR A CA  1 
ATOM   3093  C C   . THR A 1 418 ? 139.696 140.208 134.769 1.00 22.34  ? 418 THR A C   1 
ATOM   3094  O O   . THR A 1 418 ? 139.525 140.295 135.996 1.00 22.34  ? 418 THR A O   1 
ATOM   3095  C CB  . THR A 1 418 ? 137.891 140.735 133.105 1.00 22.34  ? 418 THR A CB  1 
ATOM   3096  O OG1 . THR A 1 418 ? 137.375 141.748 132.233 1.00 22.34  ? 418 THR A OG1 1 
ATOM   3097  C CG2 . THR A 1 418 ? 136.820 140.341 134.109 1.00 22.34  ? 418 THR A CG2 1 
ATOM   3098  N N   . LYS A 1 419 ? 140.383 139.205 134.213 1.00 20.85  ? 419 LYS A N   1 
ATOM   3099  C CA  . LYS A 1 419 ? 140.970 138.161 135.048 1.00 20.85  ? 419 LYS A CA  1 
ATOM   3100  C C   . LYS A 1 419 ? 141.975 138.742 136.037 1.00 20.85  ? 419 LYS A C   1 
ATOM   3101  O O   . LYS A 1 419 ? 141.964 138.395 137.230 1.00 20.85  ? 419 LYS A O   1 
ATOM   3102  C CB  . LYS A 1 419 ? 141.631 137.107 134.160 1.00 20.85  ? 419 LYS A CB  1 
ATOM   3103  C CG  . LYS A 1 419 ? 142.352 136.005 134.908 1.00 20.85  ? 419 LYS A CG  1 
ATOM   3104  C CD  . LYS A 1 419 ? 143.031 135.060 133.936 1.00 20.85  ? 419 LYS A CD  1 
ATOM   3105  C CE  . LYS A 1 419 ? 143.311 133.713 134.570 1.00 20.85  ? 419 LYS A CE  1 
ATOM   3106  N NZ  . LYS A 1 419 ? 144.701 133.260 134.306 1.00 20.85  ? 419 LYS A NZ  1 
ATOM   3107  N N   . VAL A 1 420 ? 142.841 139.642 135.561 1.00 21.71  ? 420 VAL A N   1 
ATOM   3108  C CA  . VAL A 1 420 ? 143.872 140.216 136.424 1.00 21.71  ? 420 VAL A CA  1 
ATOM   3109  C C   . VAL A 1 420 ? 143.237 141.000 137.567 1.00 21.71  ? 420 VAL A C   1 
ATOM   3110  O O   . VAL A 1 420 ? 143.640 140.872 138.732 1.00 21.71  ? 420 VAL A O   1 
ATOM   3111  C CB  . VAL A 1 420 ? 144.833 141.092 135.601 1.00 21.71  ? 420 VAL A CB  1 
ATOM   3112  C CG1 . VAL A 1 420 ? 145.714 141.923 136.518 1.00 21.71  ? 420 VAL A CG1 1 
ATOM   3113  C CG2 . VAL A 1 420 ? 145.681 140.229 134.685 1.00 21.71  ? 420 VAL A CG2 1 
ATOM   3114  N N   . ASP A 1 421 ? 142.233 141.825 137.252 1.00 22.99  ? 421 ASP A N   1 
ATOM   3115  C CA  . ASP A 1 421 ? 141.596 142.632 138.289 1.00 22.99  ? 421 ASP A CA  1 
ATOM   3116  C C   . ASP A 1 421 ? 140.924 141.757 139.341 1.00 22.99  ? 421 ASP A C   1 
ATOM   3117  O O   . ASP A 1 421 ? 141.054 142.007 140.552 1.00 22.99  ? 421 ASP A O   1 
ATOM   3118  C CB  . ASP A 1 421 ? 140.580 143.585 137.662 1.00 22.99  ? 421 ASP A CB  1 
ATOM   3119  C CG  . ASP A 1 421 ? 141.229 144.636 136.787 1.00 22.99  ? 421 ASP A CG  1 
ATOM   3120  O OD1 . ASP A 1 421 ? 142.463 144.802 136.867 1.00 22.99  ? 421 ASP A OD1 1 
ATOM   3121  O OD2 . ASP A 1 421 ? 140.504 145.299 136.017 1.00 22.99  ? 421 ASP A OD2 1 
ATOM   3122  N N   . LEU A 1 422 ? 140.208 140.717 138.900 1.00 21.04  ? 422 LEU A N   1 
ATOM   3123  C CA  . LEU A 1 422 ? 139.521 139.851 139.852 1.00 21.04  ? 422 LEU A CA  1 
ATOM   3124  C C   . LEU A 1 422 ? 140.509 139.144 140.774 1.00 21.04  ? 422 LEU A C   1 
ATOM   3125  O O   . LEU A 1 422 ? 140.291 139.068 141.992 1.00 21.04  ? 422 LEU A O   1 
ATOM   3126  C CB  . LEU A 1 422 ? 138.652 138.840 139.105 1.00 21.04  ? 422 LEU A CB  1 
ATOM   3127  C CG  . LEU A 1 422 ? 137.289 139.364 138.643 1.00 21.04  ? 422 LEU A CG  1 
ATOM   3128  C CD1 . LEU A 1 422 ? 136.747 138.525 137.500 1.00 21.04  ? 422 LEU A CD1 1 
ATOM   3129  C CD2 . LEU A 1 422 ? 136.302 139.400 139.796 1.00 21.04  ? 422 LEU A CD2 1 
ATOM   3130  N N   . TRP A 1 423 ? 141.617 138.639 140.220 1.00 20.49  ? 423 TRP A N   1 
ATOM   3131  C CA  . TRP A 1 423 ? 142.569 137.934 141.072 1.00 20.49  ? 423 TRP A CA  1 
ATOM   3132  C C   . TRP A 1 423 ? 143.292 138.880 142.027 1.00 20.49  ? 423 TRP A C   1 
ATOM   3133  O O   . TRP A 1 423 ? 143.595 138.494 143.166 1.00 20.49  ? 423 TRP A O   1 
ATOM   3134  C CB  . TRP A 1 423 ? 143.564 137.147 140.220 1.00 20.49  ? 423 TRP A CB  1 
ATOM   3135  C CG  . TRP A 1 423 ? 143.040 135.793 139.852 1.00 20.49  ? 423 TRP A CG  1 
ATOM   3136  C CD1 . TRP A 1 423 ? 142.764 135.333 138.599 1.00 20.49  ? 423 TRP A CD1 1 
ATOM   3137  C CD2 . TRP A 1 423 ? 142.694 134.733 140.752 1.00 20.49  ? 423 TRP A CD2 1 
ATOM   3138  N NE1 . TRP A 1 423 ? 142.284 134.049 138.660 1.00 20.49  ? 423 TRP A NE1 1 
ATOM   3139  C CE2 . TRP A 1 423 ? 142.229 133.658 139.971 1.00 20.49  ? 423 TRP A CE2 1 
ATOM   3140  C CE3 . TRP A 1 423 ? 142.739 134.586 142.142 1.00 20.49  ? 423 TRP A CE3 1 
ATOM   3141  C CZ2 . TRP A 1 423 ? 141.813 132.453 140.533 1.00 20.49  ? 423 TRP A CZ2 1 
ATOM   3142  C CZ3 . TRP A 1 423 ? 142.325 133.392 142.697 1.00 20.49  ? 423 TRP A CZ3 1 
ATOM   3143  C CH2 . TRP A 1 423 ? 141.867 132.341 141.895 1.00 20.49  ? 423 TRP A CH2 1 
ATOM   3144  N N   . SER A 1 424 ? 143.565 140.117 141.600 1.00 21.39  ? 424 SER A N   1 
ATOM   3145  C CA  . SER A 1 424 ? 144.164 141.086 142.515 1.00 21.39  ? 424 SER A CA  1 
ATOM   3146  C C   . SER A 1 424 ? 143.239 141.379 143.692 1.00 21.39  ? 424 SER A C   1 
ATOM   3147  O O   . SER A 1 424 ? 143.683 141.427 144.852 1.00 21.39  ? 424 SER A O   1 
ATOM   3148  C CB  . SER A 1 424 ? 144.502 142.373 141.766 1.00 21.39  ? 424 SER A CB  1 
ATOM   3149  O OG  . SER A 1 424 ? 145.330 142.109 140.649 1.00 21.39  ? 424 SER A OG  1 
ATOM   3150  N N   . TYR A 1 425 ? 141.944 141.570 143.414 1.00 22.13  ? 425 TYR A N   1 
ATOM   3151  C CA  . TYR A 1 425 ? 140.993 141.786 144.502 1.00 22.13  ? 425 TYR A CA  1 
ATOM   3152  C C   . TYR A 1 425 ? 140.964 140.593 145.451 1.00 22.13  ? 425 TYR A C   1 
ATOM   3153  O O   . TYR A 1 425 ? 140.935 140.761 146.682 1.00 22.13  ? 425 TYR A O   1 
ATOM   3154  C CB  . TYR A 1 425 ? 139.598 142.057 143.937 1.00 22.13  ? 425 TYR A CB  1 
ATOM   3155  C CG  . TYR A 1 425 ? 138.519 142.142 144.994 1.00 22.13  ? 425 TYR A CG  1 
ATOM   3156  C CD1 . TYR A 1 425 ? 138.242 143.340 145.635 1.00 22.13  ? 425 TYR A CD1 1 
ATOM   3157  C CD2 . TYR A 1 425 ? 137.777 141.023 145.350 1.00 22.13  ? 425 TYR A CD2 1 
ATOM   3158  C CE1 . TYR A 1 425 ? 137.261 143.420 146.603 1.00 22.13  ? 425 TYR A CE1 1 
ATOM   3159  C CE2 . TYR A 1 425 ? 136.799 141.094 146.315 1.00 22.13  ? 425 TYR A CE2 1 
ATOM   3160  C CZ  . TYR A 1 425 ? 136.544 142.294 146.938 1.00 22.13  ? 425 TYR A CZ  1 
ATOM   3161  O OH  . TYR A 1 425 ? 135.565 142.366 147.899 1.00 22.13  ? 425 TYR A OH  1 
ATOM   3162  N N   . ASN A 1 426 ? 140.963 139.378 144.893 1.00 22.20  ? 426 ASN A N   1 
ATOM   3163  C CA  . ASN A 1 426 ? 140.933 138.181 145.727 1.00 22.20  ? 426 ASN A CA  1 
ATOM   3164  C C   . ASN A 1 426 ? 142.137 138.131 146.658 1.00 22.20  ? 426 ASN A C   1 
ATOM   3165  O O   . ASN A 1 426 ? 142.003 137.846 147.856 1.00 22.20  ? 426 ASN A O   1 
ATOM   3166  C CB  . ASN A 1 426 ? 140.885 136.932 144.847 1.00 22.20  ? 426 ASN A CB  1 
ATOM   3167  C CG  . ASN A 1 426 ? 139.489 136.614 144.362 1.00 22.20  ? 426 ASN A CG  1 
ATOM   3168  O OD1 . ASN A 1 426 ? 138.507 137.172 144.848 1.00 22.20  ? 426 ASN A OD1 1 
ATOM   3169  N ND2 . ASN A 1 426 ? 139.393 135.708 143.399 1.00 22.20  ? 426 ASN A ND2 1 
ATOM   3170  N N   . ALA A 1 427 ? 143.327 138.412 146.120 1.00 24.43  ? 427 ALA A N   1 
ATOM   3171  C CA  . ALA A 1 427 ? 144.540 138.364 146.934 1.00 24.43  ? 427 ALA A CA  1 
ATOM   3172  C C   . ALA A 1 427 ? 144.488 139.385 148.066 1.00 24.43  ? 427 ALA A C   1 
ATOM   3173  O O   . ALA A 1 427 ? 144.816 139.071 149.221 1.00 24.43  ? 427 ALA A O   1 
ATOM   3174  C CB  . ALA A 1 427 ? 145.768 138.597 146.055 1.00 24.43  ? 427 ALA A CB  1 
ATOM   3175  N N   . GLU A 1 428 ? 144.069 140.615 147.752 1.00 29.03  ? 428 GLU A N   1 
ATOM   3176  C CA  . GLU A 1 428 ? 144.002 141.652 148.781 1.00 29.03  ? 428 GLU A CA  1 
ATOM   3177  C C   . GLU A 1 428 ? 143.064 141.245 149.916 1.00 29.03  ? 428 GLU A C   1 
ATOM   3178  O O   . GLU A 1 428 ? 143.432 141.301 151.103 1.00 29.03  ? 428 GLU A O   1 
ATOM   3179  C CB  . GLU A 1 428 ? 143.552 142.972 148.156 1.00 29.03  ? 428 GLU A CB  1 
ATOM   3180  C CG  . GLU A 1 428 ? 143.746 144.191 149.041 1.00 29.03  ? 428 GLU A CG  1 
ATOM   3181  C CD  . GLU A 1 428 ? 145.159 144.737 148.980 1.00 29.03  ? 428 GLU A CD  1 
ATOM   3182  O OE1 . GLU A 1 428 ? 145.695 145.126 150.038 1.00 29.03  ? 428 GLU A OE1 1 
ATOM   3183  O OE2 . GLU A 1 428 ? 145.733 144.781 147.873 1.00 29.03  ? 428 GLU A OE2 1 
ATOM   3184  N N   . LEU A 1 429 ? 141.845 140.820 149.565 1.00 27.46  ? 429 LEU A N   1 
ATOM   3185  C CA  . LEU A 1 429 ? 140.872 140.467 150.595 1.00 27.46  ? 429 LEU A CA  1 
ATOM   3186  C C   . LEU A 1 429 ? 141.352 139.285 151.429 1.00 27.46  ? 429 LEU A C   1 
ATOM   3187  O O   . LEU A 1 429 ? 141.195 139.278 152.660 1.00 27.46  ? 429 LEU A O   1 
ATOM   3188  C CB  . LEU A 1 429 ? 139.516 140.162 149.959 1.00 27.46  ? 429 LEU A CB  1 
ATOM   3189  C CG  . LEU A 1 429 ? 138.416 139.718 150.925 1.00 27.46  ? 429 LEU A CG  1 
ATOM   3190  C CD1 . LEU A 1 429 ? 137.997 140.864 151.830 1.00 27.46  ? 429 LEU A CD1 1 
ATOM   3191  C CD2 . LEU A 1 429 ? 137.222 139.166 150.171 1.00 27.46  ? 429 LEU A CD2 1 
ATOM   3192  N N   . LEU A 1 430 ? 141.940 138.275 150.780 1.00 28.52  ? 430 LEU A N   1 
ATOM   3193  C CA  . LEU A 1 430 ? 142.416 137.105 151.509 1.00 28.52  ? 430 LEU A CA  1 
ATOM   3194  C C   . LEU A 1 430 ? 143.486 137.486 152.522 1.00 28.52  ? 430 LEU A C   1 
ATOM   3195  O O   . LEU A 1 430 ? 143.446 137.047 153.680 1.00 28.52  ? 430 LEU A O   1 
ATOM   3196  C CB  . LEU A 1 430 ? 142.952 136.062 150.529 1.00 28.52  ? 430 LEU A CB  1 
ATOM   3197  C CG  . LEU A 1 430 ? 143.561 134.801 151.143 1.00 28.52  ? 430 LEU A CG  1 
ATOM   3198  C CD1 . LEU A 1 430 ? 142.481 133.932 151.763 1.00 28.52  ? 430 LEU A CD1 1 
ATOM   3199  C CD2 . LEU A 1 430 ? 144.347 134.026 150.101 1.00 28.52  ? 430 LEU A CD2 1 
ATOM   3200  N N   . VAL A 1 431 ? 144.453 138.309 152.106 1.00 29.16  ? 431 VAL A N   1 
ATOM   3201  C CA  . VAL A 1 431 ? 145.531 138.685 153.018 1.00 29.16  ? 431 VAL A CA  1 
ATOM   3202  C C   . VAL A 1 431 ? 144.976 139.444 154.217 1.00 29.16  ? 431 VAL A C   1 
ATOM   3203  O O   . VAL A 1 431 ? 145.350 139.176 155.371 1.00 29.16  ? 431 VAL A O   1 
ATOM   3204  C CB  . VAL A 1 431 ? 146.605 139.497 152.272 1.00 29.16  ? 431 VAL A CB  1 
ATOM   3205  C CG1 . VAL A 1 431 ? 147.583 140.116 153.252 1.00 29.16  ? 431 VAL A CG1 1 
ATOM   3206  C CG2 . VAL A 1 431 ? 147.340 138.610 151.283 1.00 29.16  ? 431 VAL A CG2 1 
ATOM   3207  N N   . ALA A 1 432 ? 144.062 140.390 153.971 1.00 31.76  ? 432 ALA A N   1 
ATOM   3208  C CA  . ALA A 1 432 ? 143.500 141.160 155.080 1.00 31.76  ? 432 ALA A CA  1 
ATOM   3209  C C   . ALA A 1 432 ? 142.761 140.257 156.068 1.00 31.76  ? 432 ALA A C   1 
ATOM   3210  O O   . ALA A 1 432 ? 142.935 140.374 157.292 1.00 31.76  ? 432 ALA A O   1 
ATOM   3211  C CB  . ALA A 1 432 ? 142.571 142.249 154.544 1.00 31.76  ? 432 ALA A CB  1 
ATOM   3212  N N   . LEU A 1 433 ? 141.938 139.339 155.550 1.00 32.34  ? 433 LEU A N   1 
ATOM   3213  C CA  . LEU A 1 433 ? 141.172 138.456 156.426 1.00 32.34  ? 433 LEU A CA  1 
ATOM   3214  C C   . LEU A 1 433 ? 142.086 137.568 157.263 1.00 32.34  ? 433 LEU A C   1 
ATOM   3215  O O   . LEU A 1 433 ? 141.862 137.390 158.470 1.00 32.34  ? 433 LEU A O   1 
ATOM   3216  C CB  . LEU A 1 433 ? 140.213 137.602 155.597 1.00 32.34  ? 433 LEU A CB  1 
ATOM   3217  C CG  . LEU A 1 433 ? 138.794 138.134 155.400 1.00 32.34  ? 433 LEU A CG  1 
ATOM   3218  C CD1 . LEU A 1 433 ? 137.973 137.152 154.583 1.00 32.34  ? 433 LEU A CD1 1 
ATOM   3219  C CD2 . LEU A 1 433 ? 138.131 138.409 156.737 1.00 32.34  ? 433 LEU A CD2 1 
ATOM   3220  N N   . GLU A 1 434 ? 143.121 136.998 156.638 1.00 35.81  ? 434 GLU A N   1 
ATOM   3221  C CA  . GLU A 1 434 ? 144.027 136.124 157.377 1.00 35.81  ? 434 GLU A CA  1 
ATOM   3222  C C   . GLU A 1 434 ? 144.763 136.883 158.474 1.00 35.81  ? 434 GLU A C   1 
ATOM   3223  O O   . GLU A 1 434 ? 144.931 136.367 159.587 1.00 35.81  ? 434 GLU A O   1 
ATOM   3224  C CB  . GLU A 1 434 ? 145.016 135.456 156.422 1.00 35.81  ? 434 GLU A CB  1 
ATOM   3225  C CG  . GLU A 1 434 ? 144.357 134.641 155.326 1.00 35.81  ? 434 GLU A CG  1 
ATOM   3226  C CD  . GLU A 1 434 ? 144.104 133.206 155.734 1.00 35.81  ? 434 GLU A CD  1 
ATOM   3227  O OE1 . GLU A 1 434 ? 145.043 132.563 156.243 1.00 35.81  ? 434 GLU A OE1 1 
ATOM   3228  O OE2 . GLU A 1 434 ? 142.968 132.723 155.550 1.00 35.81  ? 434 GLU A OE2 1 
ATOM   3229  N N   . ASN A 1 435 ? 145.212 138.109 158.185 1.00 35.37  ? 435 ASN A N   1 
ATOM   3230  C CA  . ASN A 1 435 ? 145.892 138.887 159.219 1.00 35.37  ? 435 ASN A CA  1 
ATOM   3231  C C   . ASN A 1 435 ? 144.965 139.179 160.395 1.00 35.37  ? 435 ASN A C   1 
ATOM   3232  O O   . ASN A 1 435 ? 145.363 139.047 161.566 1.00 35.37  ? 435 ASN A O   1 
ATOM   3233  C CB  . ASN A 1 435 ? 146.433 140.188 158.627 1.00 35.37  ? 435 ASN A CB  1 
ATOM   3234  C CG  . ASN A 1 435 ? 147.663 139.972 157.776 1.00 35.37  ? 435 ASN A CG  1 
ATOM   3235  O OD1 . ASN A 1 435 ? 148.254 138.894 157.785 1.00 35.37  ? 435 ASN A OD1 1 
ATOM   3236  N ND2 . ASN A 1 435 ? 148.057 140.997 157.036 1.00 35.37  ? 435 ASN A ND2 1 
ATOM   3237  N N   . GLN A 1 436 ? 143.719 139.566 160.102 1.00 38.67  ? 436 GLN A N   1 
ATOM   3238  C CA  . GLN A 1 436 ? 142.767 139.847 161.173 1.00 38.67  ? 436 GLN A CA  1 
ATOM   3239  C C   . GLN A 1 436 ? 142.547 138.617 162.049 1.00 38.67  ? 436 GLN A C   1 
ATOM   3240  O O   . GLN A 1 436 ? 142.556 138.706 163.286 1.00 38.67  ? 436 GLN A O   1 
ATOM   3241  C CB  . GLN A 1 436 ? 141.444 140.332 160.579 1.00 38.67  ? 436 GLN A CB  1 
ATOM   3242  C CG  . GLN A 1 436 ? 140.329 140.507 161.595 1.00 38.67  ? 436 GLN A CG  1 
ATOM   3243  C CD  . GLN A 1 436 ? 140.331 141.881 162.232 1.00 38.67  ? 436 GLN A CD  1 
ATOM   3244  O OE1 . GLN A 1 436 ? 140.708 142.868 161.604 1.00 38.67  ? 436 GLN A OE1 1 
ATOM   3245  N NE2 . GLN A 1 436 ? 139.911 141.951 163.488 1.00 38.67  ? 436 GLN A NE2 1 
ATOM   3246  N N   . HIS A 1 437 ? 142.367 137.452 161.421 1.00 39.90  ? 437 HIS A N   1 
ATOM   3247  C CA  . HIS A 1 437 ? 142.120 136.244 162.203 1.00 39.90  ? 437 HIS A CA  1 
ATOM   3248  C C   . HIS A 1 437 ? 143.343 135.824 163.012 1.00 39.90  ? 437 HIS A C   1 
ATOM   3249  O O   . HIS A 1 437 ? 143.193 135.307 164.126 1.00 39.90  ? 437 HIS A O   1 
ATOM   3250  C CB  . HIS A 1 437 ? 141.657 135.111 161.291 1.00 39.90  ? 437 HIS A CB  1 
ATOM   3251  C CG  . HIS A 1 437 ? 140.190 135.140 160.998 1.00 39.90  ? 437 HIS A CG  1 
ATOM   3252  N ND1 . HIS A 1 437 ? 139.246 134.662 161.880 1.00 39.90  ? 437 HIS A ND1 1 
ATOM   3253  C CD2 . HIS A 1 437 ? 139.503 135.599 159.925 1.00 39.90  ? 437 HIS A CD2 1 
ATOM   3254  C CE1 . HIS A 1 437 ? 138.041 134.821 161.363 1.00 39.90  ? 437 HIS A CE1 1 
ATOM   3255  N NE2 . HIS A 1 437 ? 138.169 135.387 160.177 1.00 39.90  ? 437 HIS A NE2 1 
ATOM   3256  N N   . THR A 1 438 ? 144.551 136.035 162.484 1.00 40.60  ? 438 THR A N   1 
ATOM   3257  C CA  . THR A 1 438 ? 145.755 135.728 163.254 1.00 40.60  ? 438 THR A CA  1 
ATOM   3258  C C   . THR A 1 438 ? 145.828 136.576 164.519 1.00 40.60  ? 438 THR A C   1 
ATOM   3259  O O   . THR A 1 438 ? 146.100 136.065 165.618 1.00 40.60  ? 438 THR A O   1 
ATOM   3260  C CB  . THR A 1 438 ? 147.000 135.946 162.391 1.00 40.60  ? 438 THR A CB  1 
ATOM   3261  O OG1 . THR A 1 438 ? 147.019 134.989 161.325 1.00 40.60  ? 438 THR A OG1 1 
ATOM   3262  C CG2 . THR A 1 438 ? 148.262 135.791 163.223 1.00 40.60  ? 438 THR A CG2 1 
ATOM   3263  N N   . ILE A 1 439 ? 145.577 137.882 164.382 1.00 42.36  ? 439 ILE A N   1 
ATOM   3264  C CA  . ILE A 1 439 ? 145.602 138.755 165.555 1.00 42.36  ? 439 ILE A CA  1 
ATOM   3265  C C   . ILE A 1 439 ? 144.552 138.313 166.569 1.00 42.36  ? 439 ILE A C   1 
ATOM   3266  O O   . ILE A 1 439 ? 144.820 138.236 167.782 1.00 42.36  ? 439 ILE A O   1 
ATOM   3267  C CB  . ILE A 1 439 ? 145.405 140.223 165.135 1.00 42.36  ? 439 ILE A CB  1 
ATOM   3268  C CG1 . ILE A 1 439 ? 146.541 140.670 164.213 1.00 42.36  ? 439 ILE A CG1 1 
ATOM   3269  C CG2 . ILE A 1 439 ? 145.331 141.123 166.355 1.00 42.36  ? 439 ILE A CG2 1 
ATOM   3270  C CD1 . ILE A 1 439 ? 147.902 140.628 164.863 1.00 42.36  ? 439 ILE A CD1 1 
ATOM   3271  N N   . ASP A 1 440 ? 143.345 137.997 166.086 1.00 45.27  ? 440 ASP A N   1 
ATOM   3272  C CA  . ASP A 1 440 ? 142.279 137.572 166.987 1.00 45.27  ? 440 ASP A CA  1 
ATOM   3273  C C   . ASP A 1 440 ? 142.653 136.300 167.739 1.00 45.27  ? 440 ASP A C   1 
ATOM   3274  O O   . ASP A 1 440 ? 142.423 136.201 168.951 1.00 45.27  ? 440 ASP A O   1 
ATOM   3275  C CB  . ASP A 1 440 ? 140.980 137.369 166.207 1.00 45.27  ? 440 ASP A CB  1 
ATOM   3276  C CG  . ASP A 1 440 ? 140.270 138.673 165.907 1.00 45.27  ? 440 ASP A CG  1 
ATOM   3277  O OD1 . ASP A 1 440 ? 140.697 139.720 166.438 1.00 45.27  ? 440 ASP A OD1 1 
ATOM   3278  O OD2 . ASP A 1 440 ? 139.283 138.651 165.143 1.00 45.27  ? 440 ASP A OD2 1 
ATOM   3279  N N   . LEU A 1 441 ? 143.229 135.315 167.044 1.00 44.89  ? 441 LEU A N   1 
ATOM   3280  C CA  . LEU A 1 441 ? 143.533 134.049 167.706 1.00 44.89  ? 441 LEU A CA  1 
ATOM   3281  C C   . LEU A 1 441 ? 144.647 134.214 168.733 1.00 44.89  ? 441 LEU A C   1 
ATOM   3282  O O   . LEU A 1 441 ? 144.603 133.592 169.802 1.00 44.89  ? 441 LEU A O   1 
ATOM   3283  C CB  . LEU A 1 441 ? 143.886 132.967 166.680 1.00 44.89  ? 441 LEU A CB  1 
ATOM   3284  C CG  . LEU A 1 441 ? 145.138 133.010 165.798 1.00 44.89  ? 441 LEU A CG  1 
ATOM   3285  C CD1 . LEU A 1 441 ? 146.347 132.411 166.504 1.00 44.89  ? 441 LEU A CD1 1 
ATOM   3286  C CD2 . LEU A 1 441 ? 144.879 132.281 164.494 1.00 44.89  ? 441 LEU A CD2 1 
ATOM   3287  N N   . THR A 1 442 ? 145.651 135.047 168.440 1.00 46.26  ? 442 THR A N   1 
ATOM   3288  C CA  . THR A 1 442 ? 146.701 135.270 169.434 1.00 46.26  ? 442 THR A CA  1 
ATOM   3289  C C   . THR A 1 442 ? 146.145 135.945 170.687 1.00 46.26  ? 442 THR A C   1 
ATOM   3290  O O   . THR A 1 442 ? 146.462 135.541 171.821 1.00 46.26  ? 442 THR A O   1 
ATOM   3291  C CB  . THR A 1 442 ? 147.834 136.098 168.831 1.00 46.26  ? 442 THR A CB  1 
ATOM   3292  O OG1 . THR A 1 442 ? 147.288 137.178 168.066 1.00 46.26  ? 442 THR A OG1 1 
ATOM   3293  C CG2 . THR A 1 442 ? 148.702 135.231 167.931 1.00 46.26  ? 442 THR A CG2 1 
ATOM   3294  N N   . ASP A 1 443 ? 145.295 136.964 170.505 1.00 49.28  ? 443 ASP A N   1 
ATOM   3295  C CA  . ASP A 1 443 ? 144.685 137.613 171.664 1.00 49.28  ? 443 ASP A CA  1 
ATOM   3296  C C   . ASP A 1 443 ? 143.832 136.633 172.462 1.00 49.28  ? 443 ASP A C   1 
ATOM   3297  O O   . ASP A 1 443 ? 143.858 136.636 173.701 1.00 49.28  ? 443 ASP A O   1 
ATOM   3298  C CB  . ASP A 1 443 ? 143.849 138.812 171.220 1.00 49.28  ? 443 ASP A CB  1 
ATOM   3299  C CG  . ASP A 1 443 ? 144.699 140.003 170.836 1.00 49.28  ? 443 ASP A CG  1 
ATOM   3300  O OD1 . ASP A 1 443 ? 145.818 140.132 171.373 1.00 49.28  ? 443 ASP A OD1 1 
ATOM   3301  O OD2 . ASP A 1 443 ? 144.248 140.813 170.000 1.00 49.28  ? 443 ASP A OD2 1 
ATOM   3302  N N   . SER A 1 444 ? 143.067 135.786 171.767 1.00 51.68  ? 444 SER A N   1 
ATOM   3303  C CA  . SER A 1 444 ? 142.225 134.813 172.453 1.00 51.68  ? 444 SER A CA  1 
ATOM   3304  C C   . SER A 1 444 ? 143.061 133.813 173.239 1.00 51.68  ? 444 SER A C   1 
ATOM   3305  O O   . SER A 1 444 ? 142.682 133.417 174.345 1.00 51.68  ? 444 SER A O   1 
ATOM   3306  C CB  . SER A 1 444 ? 141.330 134.090 171.448 1.00 51.68  ? 444 SER A CB  1 
ATOM   3307  O OG  . SER A 1 444 ? 140.254 134.915 171.040 1.00 51.68  ? 444 SER A OG  1 
ATOM   3308  N N   . GLU A 1 445 ? 144.196 133.383 172.683 1.00 54.69  ? 445 GLU A N   1 
ATOM   3309  C CA  . GLU A 1 445 ? 145.071 132.466 173.409 1.00 54.69  ? 445 GLU A CA  1 
ATOM   3310  C C   . GLU A 1 445 ? 145.583 133.098 174.697 1.00 54.69  ? 445 GLU A C   1 
ATOM   3311  O O   . GLU A 1 445 ? 145.561 132.470 175.768 1.00 54.69  ? 445 GLU A O   1 
ATOM   3312  C CB  . GLU A 1 445 ? 146.238 132.040 172.518 1.00 54.69  ? 445 GLU A CB  1 
ATOM   3313  C CG  . GLU A 1 445 ? 146.690 130.606 172.726 1.00 54.69  ? 445 GLU A CG  1 
ATOM   3314  C CD  . GLU A 1 445 ? 145.638 129.597 172.311 1.00 54.69  ? 445 GLU A CD  1 
ATOM   3315  O OE1 . GLU A 1 445 ? 145.033 129.776 171.233 1.00 54.69  ? 445 GLU A OE1 1 
ATOM   3316  O OE2 . GLU A 1 445 ? 145.416 128.625 173.062 1.00 54.69  ? 445 GLU A OE2 1 
ATOM   3317  N N   . MET A 1 446 ? 146.044 134.350 174.617 1.00 56.59  ? 446 MET A N   1 
ATOM   3318  C CA  . MET A 1 446 ? 146.534 135.017 175.823 1.00 56.59  ? 446 MET A CA  1 
ATOM   3319  C C   . MET A 1 446 ? 145.430 135.149 176.869 1.00 56.59  ? 446 MET A C   1 
ATOM   3320  O O   . MET A 1 446 ? 145.641 134.869 178.060 1.00 56.59  ? 446 MET A O   1 
ATOM   3321  C CB  . MET A 1 446 ? 147.109 136.389 175.474 1.00 56.59  ? 446 MET A CB  1 
ATOM   3322  C CG  . MET A 1 446 ? 147.611 137.165 176.682 1.00 56.59  ? 446 MET A CG  1 
ATOM   3323  S SD  . MET A 1 446 ? 149.349 136.860 177.050 1.00 56.59  ? 446 MET A SD  1 
ATOM   3324  C CE  . MET A 1 446 ? 149.221 136.011 178.620 1.00 56.59  ? 446 MET A CE  1 
ATOM   3325  N N   . ASN A 1 447 ? 144.235 135.562 176.437 1.00 57.73  ? 447 ASN A N   1 
ATOM   3326  C CA  . ASN A 1 447 ? 143.138 135.744 177.381 1.00 57.73  ? 447 ASN A CA  1 
ATOM   3327  C C   . ASN A 1 447 ? 142.700 134.418 177.992 1.00 57.73  ? 447 ASN A C   1 
ATOM   3328  O O   . ASN A 1 447 ? 142.350 134.362 179.175 1.00 57.73  ? 447 ASN A O   1 
ATOM   3329  C CB  . ASN A 1 447 ? 141.963 136.439 176.696 1.00 57.73  ? 447 ASN A CB  1 
ATOM   3330  C CG  . ASN A 1 447 ? 142.169 137.933 176.569 1.00 57.73  ? 447 ASN A CG  1 
ATOM   3331  O OD1 . ASN A 1 447 ? 142.535 138.604 177.533 1.00 57.73  ? 447 ASN A OD1 1 
ATOM   3332  N ND2 . ASN A 1 447 ? 141.937 138.463 175.376 1.00 57.73  ? 447 ASN A ND2 1 
ATOM   3333  N N   . LYS A 1 448 ? 142.706 133.341 177.203 1.00 59.78  ? 448 LYS A N   1 
ATOM   3334  C CA  . LYS A 1 448 ? 142.343 132.033 177.734 1.00 59.78  ? 448 LYS A CA  1 
ATOM   3335  C C   . LYS A 1 448 ? 143.345 131.564 178.779 1.00 59.78  ? 448 LYS A C   1 
ATOM   3336  O O   . LYS A 1 448 ? 142.955 130.993 179.803 1.00 59.78  ? 448 LYS A O   1 
ATOM   3337  C CB  . LYS A 1 448 ? 142.232 131.013 176.603 1.00 59.78  ? 448 LYS A CB  1 
ATOM   3338  C CG  . LYS A 1 448 ? 140.835 130.887 176.020 1.00 59.78  ? 448 LYS A CG  1 
ATOM   3339  C CD  . LYS A 1 448 ? 140.862 130.325 174.607 1.00 59.78  ? 448 LYS A CD  1 
ATOM   3340  C CE  . LYS A 1 448 ? 141.881 129.206 174.470 1.00 59.78  ? 448 LYS A CE  1 
ATOM   3341  N NZ  . LYS A 1 448 ? 141.801 128.550 173.136 1.00 59.78  ? 448 LYS A NZ  1 
ATOM   3342  N N   . LEU A 1 449 ? 144.640 131.786 178.538 1.00 63.11  ? 449 LEU A N   1 
ATOM   3343  C CA  . LEU A 1 449 ? 145.628 131.417 179.550 1.00 63.11  ? 449 LEU A CA  1 
ATOM   3344  C C   . LEU A 1 449 ? 145.424 132.216 180.833 1.00 63.11  ? 449 LEU A C   1 
ATOM   3345  O O   . LEU A 1 449 ? 145.476 131.658 181.940 1.00 63.11  ? 449 LEU A O   1 
ATOM   3346  C CB  . LEU A 1 449 ? 147.045 131.614 179.011 1.00 63.11  ? 449 LEU A CB  1 
ATOM   3347  C CG  . LEU A 1 449 ? 148.157 131.110 179.936 1.00 63.11  ? 449 LEU A CG  1 
ATOM   3348  C CD1 . LEU A 1 449 ? 147.901 129.667 180.340 1.00 63.11  ? 449 LEU A CD1 1 
ATOM   3349  C CD2 . LEU A 1 449 ? 149.521 131.251 179.283 1.00 63.11  ? 449 LEU A CD2 1 
ATOM   3350  N N   . PHE A 1 450 ? 145.174 133.524 180.707 1.00 67.57  ? 450 PHE A N   1 
ATOM   3351  C CA  . PHE A 1 450 ? 144.934 134.333 181.902 1.00 67.57  ? 450 PHE A CA  1 
ATOM   3352  C C   . PHE A 1 450 ? 143.690 133.865 182.651 1.00 67.57  ? 450 PHE A C   1 
ATOM   3353  O O   . PHE A 1 450 ? 143.683 133.815 183.887 1.00 67.57  ? 450 PHE A O   1 
ATOM   3354  C CB  . PHE A 1 450 ? 144.808 135.812 181.538 1.00 67.57  ? 450 PHE A CB  1 
ATOM   3355  C CG  . PHE A 1 450 ? 144.601 136.708 182.730 1.00 67.57  ? 450 PHE A CG  1 
ATOM   3356  C CD1 . PHE A 1 450 ? 145.679 137.140 183.485 1.00 67.57  ? 450 PHE A CD1 1 
ATOM   3357  C CD2 . PHE A 1 450 ? 143.329 137.109 183.100 1.00 67.57  ? 450 PHE A CD2 1 
ATOM   3358  C CE1 . PHE A 1 450 ? 145.491 137.960 184.581 1.00 67.57  ? 450 PHE A CE1 1 
ATOM   3359  C CE2 . PHE A 1 450 ? 143.135 137.928 184.196 1.00 67.57  ? 450 PHE A CE2 1 
ATOM   3360  C CZ  . PHE A 1 450 ? 144.217 138.354 184.937 1.00 67.57  ? 450 PHE A CZ  1 
ATOM   3361  N N   . GLU A 1 451 ? 142.623 133.531 181.922 1.00 68.77  ? 451 GLU A N   1 
ATOM   3362  C CA  . GLU A 1 451 ? 141.391 133.093 182.571 1.00 68.77  ? 451 GLU A CA  1 
ATOM   3363  C C   . GLU A 1 451 ? 141.566 131.739 183.246 1.00 68.77  ? 451 GLU A C   1 
ATOM   3364  O O   . GLU A 1 451 ? 141.006 131.505 184.321 1.00 68.77  ? 451 GLU A O   1 
ATOM   3365  C CB  . GLU A 1 451 ? 140.246 133.050 181.561 1.00 68.77  ? 451 GLU A CB  1 
ATOM   3366  C CG  . GLU A 1 451 ? 139.701 134.418 181.187 1.00 68.77  ? 451 GLU A CG  1 
ATOM   3367  C CD  . GLU A 1 451 ? 139.224 135.208 182.392 1.00 68.77  ? 451 GLU A CD  1 
ATOM   3368  O OE1 . GLU A 1 451 ? 138.557 134.617 183.267 1.00 68.77  ? 451 GLU A OE1 1 
ATOM   3369  O OE2 . GLU A 1 451 ? 139.515 136.420 182.465 1.00 68.77  ? 451 GLU A OE2 1 
ATOM   3370  N N   . LYS A 1 452 ? 142.330 130.830 182.633 1.00 69.29  ? 452 LYS A N   1 
ATOM   3371  C CA  . LYS A 1 452 ? 142.617 129.558 183.289 1.00 69.29  ? 452 LYS A CA  1 
ATOM   3372  C C   . LYS A 1 452 ? 143.401 129.772 184.578 1.00 69.29  ? 452 LYS A C   1 
ATOM   3373  O O   . LYS A 1 452 ? 143.106 129.147 185.607 1.00 69.29  ? 452 LYS A O   1 
ATOM   3374  C CB  . LYS A 1 452 ? 143.385 128.633 182.346 1.00 69.29  ? 452 LYS A CB  1 
ATOM   3375  C CG  . LYS A 1 452 ? 143.665 127.262 182.937 1.00 69.29  ? 452 LYS A CG  1 
ATOM   3376  C CD  . LYS A 1 452 ? 144.119 126.278 181.875 1.00 69.29  ? 452 LYS A CD  1 
ATOM   3377  C CE  . LYS A 1 452 ? 145.627 126.106 181.888 1.00 69.29  ? 452 LYS A CE  1 
ATOM   3378  N NZ  . LYS A 1 452 ? 146.060 125.123 182.920 1.00 69.29  ? 452 LYS A NZ  1 
ATOM   3379  N N   . THR A 1 453 ? 144.400 130.659 184.543 1.00 72.58  ? 453 THR A N   1 
ATOM   3380  C CA  . THR A 1 453 ? 145.164 130.949 185.754 1.00 72.58  ? 453 THR A CA  1 
ATOM   3381  C C   . THR A 1 453 ? 144.277 131.559 186.834 1.00 72.58  ? 453 THR A C   1 
ATOM   3382  O O   . THR A 1 453 ? 144.406 131.222 188.017 1.00 72.58  ? 453 THR A O   1 
ATOM   3383  C CB  . THR A 1 453 ? 146.335 131.876 185.434 1.00 72.58  ? 453 THR A CB  1 
ATOM   3384  O OG1 . THR A 1 453 ? 147.120 131.307 184.378 1.00 72.58  ? 453 THR A OG1 1 
ATOM   3385  C CG2 . THR A 1 453 ? 147.212 132.068 186.661 1.00 72.58  ? 453 THR A CG2 1 
ATOM   3386  N N   . ARG A 1 454 ? 143.372 132.462 186.447 1.00 75.49  ? 454 ARG A N   1 
ATOM   3387  C CA  . ARG A 1 454 ? 142.438 133.035 187.413 1.00 75.49  ? 454 ARG A CA  1 
ATOM   3388  C C   . ARG A 1 454 ? 141.521 131.971 187.998 1.00 75.49  ? 454 ARG A C   1 
ATOM   3389  O O   . ARG A 1 454 ? 141.252 131.963 189.203 1.00 75.49  ? 454 ARG A O   1 
ATOM   3390  C CB  . ARG A 1 454 ? 141.601 134.132 186.759 1.00 75.49  ? 454 ARG A CB  1 
ATOM   3391  C CG  . ARG A 1 454 ? 140.541 134.710 187.683 1.00 75.49  ? 454 ARG A CG  1 
ATOM   3392  C CD  . ARG A 1 454 ? 139.497 135.506 186.926 1.00 75.49  ? 454 ARG A CD  1 
ATOM   3393  N NE  . ARG A 1 454 ? 140.028 136.779 186.456 1.00 75.49  ? 454 ARG A NE  1 
ATOM   3394  C CZ  . ARG A 1 454 ? 140.087 137.882 187.190 1.00 75.49  ? 454 ARG A CZ  1 
ATOM   3395  N NH1 . ARG A 1 454 ? 139.674 137.899 188.447 1.00 75.49  ? 454 ARG A NH1 1 
ATOM   3396  N NH2 . ARG A 1 454 ? 140.578 138.994 186.651 1.00 75.49  ? 454 ARG A NH2 1 
ATOM   3397  N N   . ARG A 1 455 ? 141.017 131.076 187.152 1.00 76.76  ? 455 ARG A N   1 
ATOM   3398  C CA  . ARG A 1 455 ? 140.063 130.071 187.597 1.00 76.76  ? 455 ARG A CA  1 
ATOM   3399  C C   . ARG A 1 455 ? 140.710 129.051 188.523 1.00 76.76  ? 455 ARG A C   1 
ATOM   3400  O O   . ARG A 1 455 ? 140.043 128.517 189.418 1.00 76.76  ? 455 ARG A O   1 
ATOM   3401  C CB  . ARG A 1 455 ? 139.436 129.402 186.372 1.00 76.76  ? 455 ARG A CB  1 
ATOM   3402  C CG  . ARG A 1 455 ? 138.327 128.416 186.681 1.00 76.76  ? 455 ARG A CG  1 
ATOM   3403  C CD  . ARG A 1 455 ? 137.700 127.847 185.406 1.00 76.76  ? 455 ARG A CD  1 
ATOM   3404  N NE  . ARG A 1 455 ? 138.643 127.053 184.629 1.00 76.76  ? 455 ARG A NE  1 
ATOM   3405  C CZ  . ARG A 1 455 ? 139.097 127.382 183.426 1.00 76.76  ? 455 ARG A CZ  1 
ATOM   3406  N NH1 . ARG A 1 455 ? 138.667 128.466 182.797 1.00 76.76  ? 455 ARG A NH1 1 
ATOM   3407  N NH2 . ARG A 1 455 ? 139.991 126.595 182.833 1.00 76.76  ? 455 ARG A NH2 1 
ATOM   3408  N N   . GLN A 1 456 ? 142.001 128.773 188.327 1.00 82.06  ? 456 GLN A N   1 
ATOM   3409  C CA  . GLN A 1 456 ? 142.698 127.851 189.218 1.00 82.06  ? 456 GLN A CA  1 
ATOM   3410  C C   . GLN A 1 456 ? 142.808 128.417 190.632 1.00 82.06  ? 456 GLN A C   1 
ATOM   3411  O O   . GLN A 1 456 ? 142.648 127.685 191.615 1.00 82.06  ? 456 GLN A O   1 
ATOM   3412  C CB  . GLN A 1 456 ? 144.079 127.524 188.651 1.00 82.06  ? 456 GLN A CB  1 
ATOM   3413  C CG  . GLN A 1 456 ? 144.832 126.470 189.441 1.00 82.06  ? 456 GLN A CG  1 
ATOM   3414  C CD  . GLN A 1 456 ? 146.139 126.066 188.793 1.00 82.06  ? 456 GLN A CD  1 
ATOM   3415  O OE1 . GLN A 1 456 ? 146.852 125.202 189.299 1.00 82.06  ? 456 GLN A OE1 1 
ATOM   3416  N NE2 . GLN A 1 456 ? 146.455 126.682 187.662 1.00 82.06  ? 456 GLN A NE2 1 
ATOM   3417  N N   . LEU A 1 457 ? 143.078 129.717 190.755 1.00 86.09  ? 457 LEU A N   1 
ATOM   3418  C CA  . LEU A 1 457 ? 143.143 130.387 192.054 1.00 86.09  ? 457 LEU A CA  1 
ATOM   3419  C C   . LEU A 1 457 ? 141.750 130.913 192.376 1.00 86.09  ? 457 LEU A C   1 
ATOM   3420  O O   . LEU A 1 457 ? 141.330 131.950 191.860 1.00 86.09  ? 457 LEU A O   1 
ATOM   3421  C CB  . LEU A 1 457 ? 144.169 131.514 192.030 1.00 86.09  ? 457 LEU A CB  1 
ATOM   3422  C CG  . LEU A 1 457 ? 145.625 131.149 191.734 1.00 86.09  ? 457 LEU A CG  1 
ATOM   3423  C CD1 . LEU A 1 457 ? 146.426 132.401 191.449 1.00 86.09  ? 457 LEU A CD1 1 
ATOM   3424  C CD2 . LEU A 1 457 ? 146.234 130.383 192.893 1.00 86.09  ? 457 LEU A CD2 1 
ATOM   3425  N N   . ARG A 1 458 ? 141.035 130.214 193.256 1.00 90.03  ? 458 ARG A N   1 
ATOM   3426  C CA  . ARG A 1 458 ? 139.627 130.531 193.462 1.00 90.03  ? 458 ARG A CA  1 
ATOM   3427  C C   . ARG A 1 458 ? 139.458 131.748 194.368 1.00 90.03  ? 458 ARG A C   1 
ATOM   3428  O O   . ARG A 1 458 ? 138.920 132.778 193.947 1.00 90.03  ? 458 ARG A O   1 
ATOM   3429  C CB  . ARG A 1 458 ? 138.901 129.311 194.035 1.00 90.03  ? 458 ARG A CB  1 
ATOM   3430  C CG  . ARG A 1 458 ? 138.814 128.122 193.094 1.00 90.03  ? 458 ARG A CG  1 
ATOM   3431  C CD  . ARG A 1 458 ? 138.104 126.938 193.746 1.00 90.03  ? 458 ARG A CD  1 
ATOM   3432  N NE  . ARG A 1 458 ? 136.696 127.209 194.010 1.00 90.03  ? 458 ARG A NE  1 
ATOM   3433  C CZ  . ARG A 1 458 ? 135.897 126.413 194.708 1.00 90.03  ? 458 ARG A CZ  1 
ATOM   3434  N NH1 . ARG A 1 458 ? 136.334 125.278 195.226 1.00 90.03  ? 458 ARG A NH1 1 
ATOM   3435  N NH2 . ARG A 1 458 ? 134.628 126.762 194.888 1.00 90.03  ? 458 ARG A NH2 1 
ATOM   3436  N N   . GLU A 1 459 ? 139.928 131.657 195.614 1.00 95.67  ? 459 GLU A N   1 
ATOM   3437  C CA  . GLU A 1 459 ? 139.824 132.761 196.559 1.00 95.67  ? 459 GLU A CA  1 
ATOM   3438  C C   . GLU A 1 459 ? 141.148 133.171 197.192 1.00 95.67  ? 459 GLU A C   1 
ATOM   3439  O O   . GLU A 1 459 ? 141.161 134.102 198.005 1.00 95.67  ? 459 GLU A O   1 
ATOM   3440  C CB  . GLU A 1 459 ? 138.819 132.425 197.672 1.00 95.67  ? 459 GLU A CB  1 
ATOM   3441  C CG  . GLU A 1 459 ? 139.272 131.327 198.624 1.00 95.67  ? 459 GLU A CG  1 
ATOM   3442  C CD  . GLU A 1 459 ? 138.953 129.939 198.097 1.00 95.67  ? 459 GLU A CD  1 
ATOM   3443  O OE1 . GLU A 1 459 ? 138.661 129.818 196.898 1.00 95.67  ? 459 GLU A OE1 1 
ATOM   3444  O OE2 . GLU A 1 459 ? 139.002 128.967 198.877 1.00 95.67  ? 459 GLU A OE2 1 
ATOM   3445  N N   . ASN A 1 460 ? 142.260 132.522 196.846 1.00 96.00  ? 460 ASN A N   1 
ATOM   3446  C CA  . ASN A 1 460 ? 143.529 132.831 197.492 1.00 96.00  ? 460 ASN A CA  1 
ATOM   3447  C C   . ASN A 1 460 ? 144.272 133.996 196.851 1.00 96.00  ? 460 ASN A C   1 
ATOM   3448  O O   . ASN A 1 460 ? 145.335 134.374 197.353 1.00 96.00  ? 460 ASN A O   1 
ATOM   3449  C CB  . ASN A 1 460 ? 144.433 131.596 197.502 1.00 96.00  ? 460 ASN A CB  1 
ATOM   3450  C CG  . ASN A 1 460 ? 143.796 130.413 198.201 1.00 96.00  ? 460 ASN A CG  1 
ATOM   3451  O OD1 . ASN A 1 460 ? 142.777 130.552 198.877 1.00 96.00  ? 460 ASN A OD1 1 
ATOM   3452  N ND2 . ASN A 1 460 ? 144.399 129.241 198.051 1.00 96.00  ? 460 ASN A ND2 1 
ATOM   3453  N N   . ALA A 1 461 ? 143.752 134.576 195.771 1.00 93.37  ? 461 ALA A N   1 
ATOM   3454  C CA  . ALA A 1 461 ? 144.457 135.643 195.077 1.00 93.37  ? 461 ALA A CA  1 
ATOM   3455  C C   . ALA A 1 461 ? 143.473 136.709 194.618 1.00 93.37  ? 461 ALA A C   1 
ATOM   3456  O O   . ALA A 1 461 ? 142.283 136.449 194.427 1.00 93.37  ? 461 ALA A O   1 
ATOM   3457  C CB  . ALA A 1 461 ? 145.249 135.108 193.876 1.00 93.37  ? 461 ALA A CB  1 
ATOM   3458  N N   . GLU A 1 462 ? 143.994 137.920 194.438 1.00 91.20  ? 462 GLU A N   1 
ATOM   3459  C CA  . GLU A 1 462 ? 143.235 139.048 193.917 1.00 91.20  ? 462 GLU A CA  1 
ATOM   3460  C C   . GLU A 1 462 ? 143.926 139.594 192.675 1.00 91.20  ? 462 GLU A C   1 
ATOM   3461  O O   . GLU A 1 462 ? 145.158 139.612 192.597 1.00 91.20  ? 462 GLU A O   1 
ATOM   3462  C CB  . GLU A 1 462 ? 143.089 140.160 194.962 1.00 91.20  ? 462 GLU A CB  1 
ATOM   3463  C CG  . GLU A 1 462 ? 142.231 139.786 196.159 1.00 91.20  ? 462 GLU A CG  1 
ATOM   3464  C CD  . GLU A 1 462 ? 142.128 140.908 197.176 1.00 91.20  ? 462 GLU A CD  1 
ATOM   3465  O OE1 . GLU A 1 462 ? 142.826 141.929 197.007 1.00 91.20  ? 462 GLU A OE1 1 
ATOM   3466  O OE2 . GLU A 1 462 ? 141.347 140.771 198.140 1.00 91.20  ? 462 GLU A OE2 1 
ATOM   3467  N N   . ASP A 1 463 ? 143.127 140.043 191.711 1.00 85.49  ? 463 ASP A N   1 
ATOM   3468  C CA  . ASP A 1 463 ? 143.655 140.572 190.460 1.00 85.49  ? 463 ASP A CA  1 
ATOM   3469  C C   . ASP A 1 463 ? 144.235 141.954 190.739 1.00 85.49  ? 463 ASP A C   1 
ATOM   3470  O O   . ASP A 1 463 ? 143.537 142.836 191.249 1.00 85.49  ? 463 ASP A O   1 
ATOM   3471  C CB  . ASP A 1 463 ? 142.543 140.617 189.407 1.00 85.49  ? 463 ASP A CB  1 
ATOM   3472  C CG  . ASP A 1 463 ? 142.938 141.348 188.117 1.00 85.49  ? 463 ASP A CG  1 
ATOM   3473  O OD1 . ASP A 1 463 ? 143.937 142.094 188.070 1.00 85.49  ? 463 ASP A OD1 1 
ATOM   3474  O OD2 . ASP A 1 463 ? 142.215 141.164 187.116 1.00 85.49  ? 463 ASP A OD2 1 
ATOM   3475  N N   . MET A 1 464 ? 145.510 142.144 190.395 1.00 83.12  ? 464 MET A N   1 
ATOM   3476  C CA  . MET A 1 464 ? 146.209 143.388 190.688 1.00 83.12  ? 464 MET A CA  1 
ATOM   3477  C C   . MET A 1 464 ? 145.921 144.492 189.679 1.00 83.12  ? 464 MET A C   1 
ATOM   3478  O O   . MET A 1 464 ? 146.355 145.629 189.894 1.00 83.12  ? 464 MET A O   1 
ATOM   3479  C CB  . MET A 1 464 ? 147.717 143.139 190.756 1.00 83.12  ? 464 MET A CB  1 
ATOM   3480  C CG  . MET A 1 464 ? 148.219 142.771 192.141 1.00 83.12  ? 464 MET A CG  1 
ATOM   3481  S SD  . MET A 1 464 ? 150.017 142.773 192.258 1.00 83.12  ? 464 MET A SD  1 
ATOM   3482  C CE  . MET A 1 464 ? 150.424 144.177 191.223 1.00 83.12  ? 464 MET A CE  1 
ATOM   3483  N N   . GLY A 1 465 ? 145.213 144.194 188.592 1.00 81.40  ? 465 GLY A N   1 
ATOM   3484  C CA  . GLY A 1 465 ? 144.829 145.204 187.630 1.00 81.40  ? 465 GLY A CA  1 
ATOM   3485  C C   . GLY A 1 465 ? 145.751 145.373 186.443 1.00 81.40  ? 465 GLY A C   1 
ATOM   3486  O O   . GLY A 1 465 ? 145.408 146.121 185.519 1.00 81.40  ? 465 GLY A O   1 
ATOM   3487  N N   . ASN A 1 466 ? 146.905 144.708 186.429 1.00 77.57  ? 466 ASN A N   1 
ATOM   3488  C CA  . ASN A 1 466 ? 147.863 144.828 185.336 1.00 77.57  ? 466 ASN A CA  1 
ATOM   3489  C C   . ASN A 1 466 ? 148.240 143.464 184.768 1.00 77.57  ? 466 ASN A C   1 
ATOM   3490  O O   . ASN A 1 466 ? 149.364 143.267 184.307 1.00 77.57  ? 466 ASN A O   1 
ATOM   3491  C CB  . ASN A 1 466 ? 149.114 145.577 185.795 1.00 77.57  ? 466 ASN A CB  1 
ATOM   3492  C CG  . ASN A 1 466 ? 149.722 144.983 187.049 1.00 77.57  ? 466 ASN A CG  1 
ATOM   3493  O OD1 . ASN A 1 466 ? 149.136 144.104 187.681 1.00 77.57  ? 466 ASN A OD1 1 
ATOM   3494  N ND2 . ASN A 1 466 ? 150.906 145.459 187.415 1.00 77.57  ? 466 ASN A ND2 1 
ATOM   3495  N N   . GLY A 1 467 ? 147.307 142.516 184.792 1.00 75.37  ? 467 GLY A N   1 
ATOM   3496  C CA  . GLY A 1 467 ? 147.605 141.173 184.343 1.00 75.37  ? 467 GLY A CA  1 
ATOM   3497  C C   . GLY A 1 467 ? 148.358 140.330 185.343 1.00 75.37  ? 467 GLY A C   1 
ATOM   3498  O O   . GLY A 1 467 ? 148.853 139.258 184.985 1.00 75.37  ? 467 GLY A O   1 
ATOM   3499  N N   . CYS A 1 468 ? 148.457 140.779 186.591 1.00 77.99  ? 468 CYS A N   1 
ATOM   3500  C CA  . CYS A 1 468 ? 149.172 140.068 187.636 1.00 77.99  ? 468 CYS A CA  1 
ATOM   3501  C C   . CYS A 1 468 ? 148.213 139.678 188.752 1.00 77.99  ? 468 CYS A C   1 
ATOM   3502  O O   . CYS A 1 468 ? 147.114 140.224 188.878 1.00 77.99  ? 468 CYS A O   1 
ATOM   3503  C CB  . CYS A 1 468 ? 150.317 140.917 188.204 1.00 77.99  ? 468 CYS A CB  1 
ATOM   3504  S SG  . CYS A 1 468 ? 151.612 141.316 187.010 1.00 77.99  ? 468 CYS A SG  1 
ATOM   3505  N N   . PHE A 1 469 ? 148.644 138.716 189.564 1.00 79.40  ? 469 PHE A N   1 
ATOM   3506  C CA  . PHE A 1 469 ? 147.858 138.202 190.676 1.00 79.40  ? 469 PHE A CA  1 
ATOM   3507  C C   . PHE A 1 469 ? 148.632 138.372 191.974 1.00 79.40  ? 469 PHE A C   1 
ATOM   3508  O O   . PHE A 1 469 ? 149.844 138.138 192.019 1.00 79.40  ? 469 PHE A O   1 
ATOM   3509  C CB  . PHE A 1 469 ? 147.515 136.725 190.471 1.00 79.40  ? 469 PHE A CB  1 
ATOM   3510  C CG  . PHE A 1 469 ? 146.372 136.496 189.530 1.00 79.40  ? 469 PHE A CG  1 
ATOM   3511  C CD1 . PHE A 1 469 ? 145.091 136.897 189.864 1.00 79.40  ? 469 PHE A CD1 1 
ATOM   3512  C CD2 . PHE A 1 469 ? 146.579 135.878 188.309 1.00 79.40  ? 469 PHE A CD2 1 
ATOM   3513  C CE1 . PHE A 1 469 ? 144.039 136.686 188.998 1.00 79.40  ? 469 PHE A CE1 1 
ATOM   3514  C CE2 . PHE A 1 469 ? 145.532 135.664 187.440 1.00 79.40  ? 469 PHE A CE2 1 
ATOM   3515  C CZ  . PHE A 1 469 ? 144.262 136.071 187.784 1.00 79.40  ? 469 PHE A CZ  1 
ATOM   3516  N N   . LYS A 1 470 ? 147.931 138.776 193.030 1.00 89.16  ? 470 LYS A N   1 
ATOM   3517  C CA  . LYS A 1 470 ? 148.517 138.910 194.359 1.00 89.16  ? 470 LYS A CA  1 
ATOM   3518  C C   . LYS A 1 470 ? 148.001 137.768 195.227 1.00 89.16  ? 470 LYS A C   1 
ATOM   3519  O O   . LYS A 1 470 ? 146.846 137.784 195.663 1.00 89.16  ? 470 LYS A O   1 
ATOM   3520  C CB  . LYS A 1 470 ? 148.177 140.265 194.976 1.00 89.16  ? 470 LYS A CB  1 
ATOM   3521  C CG  . LYS A 1 470 ? 148.655 140.425 196.411 1.00 89.16  ? 470 LYS A CG  1 
ATOM   3522  C CD  . LYS A 1 470 ? 148.241 141.770 196.992 1.00 89.16  ? 470 LYS A CD  1 
ATOM   3523  C CE  . LYS A 1 470 ? 148.748 141.934 198.417 1.00 89.16  ? 470 LYS A CE  1 
ATOM   3524  N NZ  . LYS A 1 470 ? 148.739 143.357 198.855 1.00 89.16  ? 470 LYS A NZ  1 
ATOM   3525  N N   . ILE A 1 471 ? 148.857 136.784 195.479 1.00 90.89  ? 471 ILE A N   1 
ATOM   3526  C CA  . ILE A 1 471 ? 148.505 135.638 196.307 1.00 90.89  ? 471 ILE A CA  1 
ATOM   3527  C C   . ILE A 1 471 ? 148.751 136.000 197.765 1.00 90.89  ? 471 ILE A C   1 
ATOM   3528  O O   . ILE A 1 471 ? 149.842 136.457 198.126 1.00 90.89  ? 471 ILE A O   1 
ATOM   3529  C CB  . ILE A 1 471 ? 149.310 134.395 195.897 1.00 90.89  ? 471 ILE A CB  1 
ATOM   3530  C CG1 . ILE A 1 471 ? 149.322 134.250 194.374 1.00 90.89  ? 471 ILE A CG1 1 
ATOM   3531  C CG2 . ILE A 1 471 ? 148.728 133.151 196.537 1.00 90.89  ? 471 ILE A CG2 1 
ATOM   3532  C CD1 . ILE A 1 471 ? 150.463 133.414 193.847 1.00 90.89  ? 471 ILE A CD1 1 
ATOM   3533  N N   . TYR A 1 472 ? 147.739 135.795 198.603 1.00 94.79  ? 472 TYR A N   1 
ATOM   3534  C CA  . TYR A 1 472 ? 147.745 136.303 199.968 1.00 94.79  ? 472 TYR A CA  1 
ATOM   3535  C C   . TYR A 1 472 ? 148.319 135.325 200.985 1.00 94.79  ? 472 TYR A C   1 
ATOM   3536  O O   . TYR A 1 472 ? 148.328 135.638 202.179 1.00 94.79  ? 472 TYR A O   1 
ATOM   3537  C CB  . TYR A 1 472 ? 146.325 136.702 200.380 1.00 94.79  ? 472 TYR A CB  1 
ATOM   3538  C CG  . TYR A 1 472 ? 145.971 138.123 200.010 1.00 94.79  ? 472 TYR A CG  1 
ATOM   3539  C CD1 . TYR A 1 472 ? 146.237 139.172 200.878 1.00 94.79  ? 472 TYR A CD1 1 
ATOM   3540  C CD2 . TYR A 1 472 ? 145.375 138.416 198.791 1.00 94.79  ? 472 TYR A CD2 1 
ATOM   3541  C CE1 . TYR A 1 472 ? 145.917 140.473 200.544 1.00 94.79  ? 472 TYR A CE1 1 
ATOM   3542  C CE2 . TYR A 1 472 ? 145.052 139.714 198.449 1.00 94.79  ? 472 TYR A CE2 1 
ATOM   3543  C CZ  . TYR A 1 472 ? 145.325 140.738 199.329 1.00 94.79  ? 472 TYR A CZ  1 
ATOM   3544  O OH  . TYR A 1 472 ? 145.006 142.033 198.994 1.00 94.79  ? 472 TYR A OH  1 
ATOM   3545  N N   . HIS A 1 473 ? 148.797 134.165 200.557 1.00 96.21  ? 473 HIS A N   1 
ATOM   3546  C CA  . HIS A 1 473 ? 149.425 133.207 201.455 1.00 96.21  ? 473 HIS A CA  1 
ATOM   3547  C C   . HIS A 1 473 ? 150.882 133.006 201.048 1.00 96.21  ? 473 HIS A C   1 
ATOM   3548  O O   . HIS A 1 473 ? 151.342 133.515 200.023 1.00 96.21  ? 473 HIS A O   1 
ATOM   3549  C CB  . HIS A 1 473 ? 148.660 131.880 201.465 1.00 96.21  ? 473 HIS A CB  1 
ATOM   3550  C CG  . HIS A 1 473 ? 148.746 131.118 200.179 1.00 96.21  ? 473 HIS A CG  1 
ATOM   3551  N ND1 . HIS A 1 473 ? 149.791 130.270 199.884 1.00 96.21  ? 473 HIS A ND1 1 
ATOM   3552  C CD2 . HIS A 1 473 ? 147.909 131.068 199.116 1.00 96.21  ? 473 HIS A CD2 1 
ATOM   3553  C CE1 . HIS A 1 473 ? 149.598 129.736 198.692 1.00 96.21  ? 473 HIS A CE1 1 
ATOM   3554  N NE2 . HIS A 1 473 ? 148.464 130.204 198.204 1.00 96.21  ? 473 HIS A NE2 1 
ATOM   3555  N N   . LYS A 1 474 ? 151.612 132.256 201.869 1.00 99.55  ? 474 LYS A N   1 
ATOM   3556  C CA  . LYS A 1 474 ? 153.026 132.000 201.617 1.00 99.55  ? 474 LYS A CA  1 
ATOM   3557  C C   . LYS A 1 474 ? 153.143 130.944 200.527 1.00 99.55  ? 474 LYS A C   1 
ATOM   3558  O O   . LYS A 1 474 ? 152.846 129.766 200.755 1.00 99.55  ? 474 LYS A O   1 
ATOM   3559  C CB  . LYS A 1 474 ? 153.727 131.558 202.899 1.00 99.55  ? 474 LYS A CB  1 
ATOM   3560  C CG  . LYS A 1 474 ? 155.240 131.473 202.779 1.00 99.55  ? 474 LYS A CG  1 
ATOM   3561  C CD  . LYS A 1 474 ? 155.878 131.101 204.106 1.00 99.55  ? 474 LYS A CD  1 
ATOM   3562  C CE  . LYS A 1 474 ? 155.778 132.244 205.102 1.00 99.55  ? 474 LYS A CE  1 
ATOM   3563  N NZ  . LYS A 1 474 ? 156.564 133.430 204.665 1.00 99.55  ? 474 LYS A NZ  1 
ATOM   3564  N N   . CYS A 1 475 ? 153.575 131.364 199.341 1.00 96.08  ? 475 CYS A N   1 
ATOM   3565  C CA  . CYS A 1 475 ? 153.633 130.511 198.159 1.00 96.08  ? 475 CYS A CA  1 
ATOM   3566  C C   . CYS A 1 475 ? 155.089 130.416 197.717 1.00 96.08  ? 475 CYS A C   1 
ATOM   3567  O O   . CYS A 1 475 ? 155.637 131.375 197.164 1.00 96.08  ? 475 CYS A O   1 
ATOM   3568  C CB  . CYS A 1 475 ? 152.740 131.076 197.053 1.00 96.08  ? 475 CYS A CB  1 
ATOM   3569  S SG  . CYS A 1 475 ? 152.501 130.043 195.589 1.00 96.08  ? 475 CYS A SG  1 
ATOM   3570  N N   . ASP A 1 476 ? 155.711 129.264 197.962 1.00 93.27  ? 476 ASP A N   1 
ATOM   3571  C CA  . ASP A 1 476 ? 157.126 129.067 197.680 1.00 93.27  ? 476 ASP A CA  1 
ATOM   3572  C C   . ASP A 1 476 ? 157.318 128.626 196.228 1.00 93.27  ? 476 ASP A C   1 
ATOM   3573  O O   . ASP A 1 476 ? 156.396 128.678 195.411 1.00 93.27  ? 476 ASP A O   1 
ATOM   3574  C CB  . ASP A 1 476 ? 157.723 128.064 198.666 1.00 93.27  ? 476 ASP A CB  1 
ATOM   3575  C CG  . ASP A 1 476 ? 157.063 126.701 198.586 1.00 93.27  ? 476 ASP A CG  1 
ATOM   3576  O OD1 . ASP A 1 476 ? 155.844 126.614 198.844 1.00 93.27  ? 476 ASP A OD1 1 
ATOM   3577  O OD2 . ASP A 1 476 ? 157.762 125.718 198.264 1.00 93.27  ? 476 ASP A OD2 1 
ATOM   3578  N N   . ASN A 1 477 ? 158.538 128.195 195.891 1.00 91.31  ? 477 ASN A N   1 
ATOM   3579  C CA  . ASN A 1 477 ? 158.832 127.795 194.517 1.00 91.31  ? 477 ASN A CA  1 
ATOM   3580  C C   . ASN A 1 477 ? 158.048 126.552 194.115 1.00 91.31  ? 477 ASN A C   1 
ATOM   3581  O O   . ASN A 1 477 ? 157.568 126.458 192.980 1.00 91.31  ? 477 ASN A O   1 
ATOM   3582  C CB  . ASN A 1 477 ? 160.333 127.563 194.345 1.00 91.31  ? 477 ASN A CB  1 
ATOM   3583  C CG  . ASN A 1 477 ? 161.113 128.858 194.248 1.00 91.31  ? 477 ASN A CG  1 
ATOM   3584  O OD1 . ASN A 1 477 ? 160.536 129.933 194.089 1.00 91.31  ? 477 ASN A OD1 1 
ATOM   3585  N ND2 . ASN A 1 477 ? 162.434 128.761 194.338 1.00 91.31  ? 477 ASN A ND2 1 
ATOM   3586  N N   . ALA A 1 478 ? 157.916 125.584 195.025 1.00 92.30  ? 478 ALA A N   1 
ATOM   3587  C CA  . ALA A 1 478 ? 157.079 124.422 194.740 1.00 92.30  ? 478 ALA A CA  1 
ATOM   3588  C C   . ALA A 1 478 ? 155.622 124.831 194.572 1.00 92.30  ? 478 ALA A C   1 
ATOM   3589  O O   . ALA A 1 478 ? 154.906 124.283 193.728 1.00 92.30  ? 478 ALA A O   1 
ATOM   3590  C CB  . ALA A 1 478 ? 157.226 123.382 195.850 1.00 92.30  ? 478 ALA A CB  1 
ATOM   3591  N N   . CYS A 1 479 ? 155.171 125.803 195.367 1.00 90.83  ? 479 CYS A N   1 
ATOM   3592  C CA  . CYS A 1 479 ? 153.829 126.356 195.210 1.00 90.83  ? 479 CYS A CA  1 
ATOM   3593  C C   . CYS A 1 479 ? 153.629 126.981 193.832 1.00 90.83  ? 479 CYS A C   1 
ATOM   3594  O O   . CYS A 1 479 ? 152.609 126.734 193.172 1.00 90.83  ? 479 CYS A O   1 
ATOM   3595  C CB  . CYS A 1 479 ? 153.585 127.380 196.316 1.00 90.83  ? 479 CYS A CB  1 
ATOM   3596  S SG  . CYS A 1 479 ? 151.998 128.209 196.303 1.00 90.83  ? 479 CYS A SG  1 
ATOM   3597  N N   . ILE A 1 480 ? 154.590 127.788 193.377 1.00 87.57  ? 480 ILE A N   1 
ATOM   3598  C CA  . ILE A 1 480 ? 154.473 128.419 192.064 1.00 87.57  ? 480 ILE A CA  1 
ATOM   3599  C C   . ILE A 1 480 ? 154.496 127.365 190.964 1.00 87.57  ? 480 ILE A C   1 
ATOM   3600  O O   . ILE A 1 480 ? 153.747 127.452 189.982 1.00 87.57  ? 480 ILE A O   1 
ATOM   3601  C CB  . ILE A 1 480 ? 155.586 129.466 191.873 1.00 87.57  ? 480 ILE A CB  1 
ATOM   3602  C CG1 . ILE A 1 480 ? 155.479 130.560 192.937 1.00 87.57  ? 480 ILE A CG1 1 
ATOM   3603  C CG2 . ILE A 1 480 ? 155.521 130.070 190.480 1.00 87.57  ? 480 ILE A CG2 1 
ATOM   3604  C CD1 . ILE A 1 480 ? 154.360 131.548 192.693 1.00 87.57  ? 480 ILE A CD1 1 
ATOM   3605  N N   . GLU A 1 481 ? 155.356 126.356 191.110 1.00 87.48  ? 481 GLU A N   1 
ATOM   3606  C CA  . GLU A 1 481 ? 155.421 125.288 190.119 1.00 87.48  ? 481 GLU A CA  1 
ATOM   3607  C C   . GLU A 1 481 ? 154.110 124.513 190.062 1.00 87.48  ? 481 GLU A C   1 
ATOM   3608  O O   . GLU A 1 481 ? 153.656 124.125 188.980 1.00 87.48  ? 481 GLU A O   1 
ATOM   3609  C CB  . GLU A 1 481 ? 156.592 124.353 190.437 1.00 87.48  ? 481 GLU A CB  1 
ATOM   3610  C CG  . GLU A 1 481 ? 156.666 123.034 189.648 1.00 87.48  ? 481 GLU A CG  1 
ATOM   3611  C CD  . GLU A 1 481 ? 156.547 123.168 188.126 1.00 87.48  ? 481 GLU A CD  1 
ATOM   3612  O OE1 . GLU A 1 481 ? 156.494 124.293 187.585 1.00 87.48  ? 481 GLU A OE1 1 
ATOM   3613  O OE2 . GLU A 1 481 ? 156.505 122.113 187.459 1.00 87.48  ? 481 GLU A OE2 1 
ATOM   3614  N N   . SER A 1 482 ? 153.490 124.273 191.220 1.00 88.47  ? 482 SER A N   1 
ATOM   3615  C CA  . SER A 1 482 ? 152.196 123.599 191.248 1.00 88.47  ? 482 SER A CA  1 
ATOM   3616  C C   . SER A 1 482 ? 151.116 124.446 190.588 1.00 88.47  ? 482 SER A C   1 
ATOM   3617  O O   . SER A 1 482 ? 150.240 123.913 189.896 1.00 88.47  ? 482 SER A O   1 
ATOM   3618  C CB  . SER A 1 482 ? 151.809 123.264 192.688 1.00 88.47  ? 482 SER A CB  1 
ATOM   3619  O OG  . SER A 1 482 ? 151.586 124.443 193.441 1.00 88.47  ? 482 SER A OG  1 
ATOM   3620  N N   . ILE A 1 483 ? 151.149 125.763 190.804 1.00 86.55  ? 483 ILE A N   1 
ATOM   3621  C CA  . ILE A 1 483 ? 150.196 126.645 190.130 1.00 86.55  ? 483 ILE A CA  1 
ATOM   3622  C C   . ILE A 1 483 ? 150.374 126.556 188.619 1.00 86.55  ? 483 ILE A C   1 
ATOM   3623  O O   . ILE A 1 483 ? 149.402 126.438 187.864 1.00 86.55  ? 483 ILE A O   1 
ATOM   3624  C CB  . ILE A 1 483 ? 150.349 128.094 190.625 1.00 86.55  ? 483 ILE A CB  1 
ATOM   3625  C CG1 . ILE A 1 483 ? 149.790 128.243 192.038 1.00 86.55  ? 483 ILE A CG1 1 
ATOM   3626  C CG2 . ILE A 1 483 ? 149.649 129.059 189.681 1.00 86.55  ? 483 ILE A CG2 1 
ATOM   3627  C CD1 . ILE A 1 483 ? 150.444 129.345 192.827 1.00 86.55  ? 483 ILE A CD1 1 
ATOM   3628  N N   . ARG A 1 484 ? 151.625 126.608 188.159 1.00 83.07  ? 484 ARG A N   1 
ATOM   3629  C CA  . ARG A 1 484 ? 151.895 126.558 186.724 1.00 83.07  ? 484 ARG A CA  1 
ATOM   3630  C C   . ARG A 1 484 ? 151.475 125.221 186.121 1.00 83.07  ? 484 ARG A C   1 
ATOM   3631  O O   . ARG A 1 484 ? 150.927 125.181 185.013 1.00 83.07  ? 484 ARG A O   1 
ATOM   3632  C CB  . ARG A 1 484 ? 153.376 126.829 186.466 1.00 83.07  ? 484 ARG A CB  1 
ATOM   3633  C CG  . ARG A 1 484 ? 153.830 128.210 186.912 1.00 83.07  ? 484 ARG A CG  1 
ATOM   3634  C CD  . ARG A 1 484 ? 155.118 128.626 186.230 1.00 83.07  ? 484 ARG A CD  1 
ATOM   3635  N NE  . ARG A 1 484 ? 156.156 127.614 186.382 1.00 83.07  ? 484 ARG A NE  1 
ATOM   3636  C CZ  . ARG A 1 484 ? 157.317 127.818 186.989 1.00 83.07  ? 484 ARG A CZ  1 
ATOM   3637  N NH1 . ARG A 1 484 ? 157.623 128.991 187.520 1.00 83.07  ? 484 ARG A NH1 1 
ATOM   3638  N NH2 . ARG A 1 484 ? 158.192 126.820 187.068 1.00 83.07  ? 484 ARG A NH2 1 
ATOM   3639  N N   . ASN A 1 485 ? 151.728 124.117 186.829 1.00 86.35  ? 485 ASN A N   1 
ATOM   3640  C CA  . ASN A 1 485 ? 151.359 122.801 186.315 1.00 86.35  ? 485 ASN A CA  1 
ATOM   3641  C C   . ASN A 1 485 ? 149.848 122.641 186.210 1.00 86.35  ? 485 ASN A C   1 
ATOM   3642  O O   . ASN A 1 485 ? 149.345 122.072 185.235 1.00 86.35  ? 485 ASN A O   1 
ATOM   3643  C CB  . ASN A 1 485 ? 151.935 121.702 187.206 1.00 86.35  ? 485 ASN A CB  1 
ATOM   3644  C CG  . ASN A 1 485 ? 153.438 121.594 187.105 1.00 86.35  ? 485 ASN A CG  1 
ATOM   3645  O OD1 . ASN A 1 485 ? 154.009 121.681 186.018 1.00 86.35  ? 485 ASN A OD1 1 
ATOM   3646  N ND2 . ASN A 1 485 ? 154.090 121.383 188.241 1.00 86.35  ? 485 ASN A ND2 1 
ATOM   3647  N N   . GLY A 1 486 ? 149.112 123.127 187.204 1.00 88.05  ? 486 GLY A N   1 
ATOM   3648  C CA  . GLY A 1 486 ? 147.686 122.900 187.290 1.00 88.05  ? 486 GLY A CA  1 
ATOM   3649  C C   . GLY A 1 486 ? 147.249 121.988 188.415 1.00 88.05  ? 486 GLY A C   1 
ATOM   3650  O O   . GLY A 1 486 ? 146.084 121.575 188.434 1.00 88.05  ? 486 GLY A O   1 
ATOM   3651  N N   . THR A 1 487 ? 148.142 121.655 189.348 1.00 90.91  ? 487 THR A N   1 
ATOM   3652  C CA  . THR A 1 487 ? 147.832 120.788 190.477 1.00 90.91  ? 487 THR A CA  1 
ATOM   3653  C C   . THR A 1 487 ? 147.727 121.571 191.784 1.00 90.91  ? 487 THR A C   1 
ATOM   3654  O O   . THR A 1 487 ? 148.009 121.040 192.861 1.00 90.91  ? 487 THR A O   1 
ATOM   3655  C CB  . THR A 1 487 ? 148.878 119.679 190.599 1.00 90.91  ? 487 THR A CB  1 
ATOM   3656  O OG1 . THR A 1 487 ? 148.567 118.843 191.721 1.00 90.91  ? 487 THR A OG1 1 
ATOM   3657  C CG2 . THR A 1 487 ? 150.273 120.268 190.773 1.00 90.91  ? 487 THR A CG2 1 
ATOM   3658  N N   . TYR A 1 488 ? 147.315 122.833 191.701 1.00 91.38  ? 488 TYR A N   1 
ATOM   3659  C CA  . TYR A 1 488 ? 147.184 123.674 192.882 1.00 91.38  ? 488 TYR A CA  1 
ATOM   3660  C C   . TYR A 1 488 ? 145.910 123.339 193.645 1.00 91.38  ? 488 TYR A C   1 
ATOM   3661  O O   . TYR A 1 488 ? 144.841 123.164 193.054 1.00 91.38  ? 488 TYR A O   1 
ATOM   3662  C CB  . TYR A 1 488 ? 147.184 125.150 192.482 1.00 91.38  ? 488 TYR A CB  1 
ATOM   3663  C CG  . TYR A 1 488 ? 146.956 126.112 193.626 1.00 91.38  ? 488 TYR A CG  1 
ATOM   3664  C CD1 . TYR A 1 488 ? 147.993 126.471 194.474 1.00 91.38  ? 488 TYR A CD1 1 
ATOM   3665  C CD2 . TYR A 1 488 ? 145.706 126.676 193.846 1.00 91.38  ? 488 TYR A CD2 1 
ATOM   3666  C CE1 . TYR A 1 488 ? 147.790 127.354 195.516 1.00 91.38  ? 488 TYR A CE1 1 
ATOM   3667  C CE2 . TYR A 1 488 ? 145.493 127.559 194.885 1.00 91.38  ? 488 TYR A CE2 1 
ATOM   3668  C CZ  . TYR A 1 488 ? 146.539 127.896 195.716 1.00 91.38  ? 488 TYR A CZ  1 
ATOM   3669  O OH  . TYR A 1 488 ? 146.335 128.776 196.753 1.00 91.38  ? 488 TYR A OH  1 
ATOM   3670  N N   . ASP A 1 489 ? 146.032 123.248 194.966 1.00 96.67  ? 489 ASP A N   1 
ATOM   3671  C CA  . ASP A 1 489 ? 144.908 122.972 195.852 1.00 96.67  ? 489 ASP A CA  1 
ATOM   3672  C C   . ASP A 1 489 ? 144.672 124.194 196.731 1.00 96.67  ? 489 ASP A C   1 
ATOM   3673  O O   . ASP A 1 489 ? 145.572 124.622 197.460 1.00 96.67  ? 489 ASP A O   1 
ATOM   3674  C CB  . ASP A 1 489 ? 145.179 121.731 196.702 1.00 96.67  ? 489 ASP A CB  1 
ATOM   3675  C CG  . ASP A 1 489 ? 143.942 121.232 197.424 1.00 96.67  ? 489 ASP A CG  1 
ATOM   3676  O OD1 . ASP A 1 489 ? 142.883 121.887 197.327 1.00 96.67  ? 489 ASP A OD1 1 
ATOM   3677  O OD2 . ASP A 1 489 ? 144.028 120.177 198.086 1.00 96.67  ? 489 ASP A OD2 1 
ATOM   3678  N N   . HIS A 1 490 ? 143.461 124.752 196.657 1.00 96.39  ? 490 HIS A N   1 
ATOM   3679  C CA  . HIS A 1 490 ? 143.138 125.950 197.424 1.00 96.39  ? 490 HIS A CA  1 
ATOM   3680  C C   . HIS A 1 490 ? 142.811 125.637 198.879 1.00 96.39  ? 490 HIS A C   1 
ATOM   3681  O O   . HIS A 1 490 ? 142.969 126.507 199.745 1.00 96.39  ? 490 HIS A O   1 
ATOM   3682  C CB  . HIS A 1 490 ? 141.964 126.683 196.775 1.00 96.39  ? 490 HIS A CB  1 
ATOM   3683  C CG  . HIS A 1 490 ? 140.688 125.901 196.781 1.00 96.39  ? 490 HIS A CG  1 
ATOM   3684  N ND1 . HIS A 1 490 ? 140.487 124.798 195.980 1.00 96.39  ? 490 HIS A ND1 1 
ATOM   3685  C CD2 . HIS A 1 490 ? 139.550 126.057 197.498 1.00 96.39  ? 490 HIS A CD2 1 
ATOM   3686  C CE1 . HIS A 1 490 ? 139.279 124.310 196.200 1.00 96.39  ? 490 HIS A CE1 1 
ATOM   3687  N NE2 . HIS A 1 490 ? 138.690 125.056 197.118 1.00 96.39  ? 490 HIS A NE2 1 
ATOM   3688  N N   . ASP A 1 491 ? 142.356 124.414 199.164 1.00 98.70  ? 491 ASP A N   1 
ATOM   3689  C CA  . ASP A 1 491 ? 141.944 124.067 200.520 1.00 98.70  ? 491 ASP A CA  1 
ATOM   3690  C C   . ASP A 1 491 ? 143.119 124.063 201.489 1.00 98.70  ? 491 ASP A C   1 
ATOM   3691  O O   . ASP A 1 491 ? 142.923 124.230 202.699 1.00 98.70  ? 491 ASP A O   1 
ATOM   3692  C CB  . ASP A 1 491 ? 141.255 122.703 200.526 1.00 98.70  ? 491 ASP A CB  1 
ATOM   3693  C CG  . ASP A 1 491 ? 139.802 122.783 200.109 1.00 98.70  ? 491 ASP A CG  1 
ATOM   3694  O OD1 . ASP A 1 491 ? 139.184 123.851 200.305 1.00 98.70  ? 491 ASP A OD1 1 
ATOM   3695  O OD2 . ASP A 1 491 ? 139.277 121.777 199.590 1.00 98.70  ? 491 ASP A OD2 1 
ATOM   3696  N N   . ILE A 1 492 ? 144.337 123.861 200.986 1.00 99.22  ? 492 ILE A N   1 
ATOM   3697  C CA  . ILE A 1 492 ? 145.507 123.849 201.859 1.00 99.22  ? 492 ILE A CA  1 
ATOM   3698  C C   . ILE A 1 492 ? 145.734 125.226 202.469 1.00 99.22  ? 492 ILE A C   1 
ATOM   3699  O O   . ILE A 1 492 ? 146.042 125.352 203.660 1.00 99.22  ? 492 ILE A O   1 
ATOM   3700  C CB  . ILE A 1 492 ? 146.746 123.359 201.087 1.00 99.22  ? 492 ILE A CB  1 
ATOM   3701  C CG1 . ILE A 1 492 ? 146.535 121.925 200.594 1.00 99.22  ? 492 ILE A CG1 1 
ATOM   3702  C CG2 . ILE A 1 492 ? 147.985 123.436 201.960 1.00 99.22  ? 492 ILE A CG2 1 
ATOM   3703  C CD1 . ILE A 1 492 ? 147.563 121.469 199.581 1.00 99.22  ? 492 ILE A CD1 1 
ATOM   3704  N N   . TYR A 1 493 ? 145.579 126.280 201.668 1.00 98.94  ? 493 TYR A N   1 
ATOM   3705  C CA  . TYR A 1 493 ? 145.861 127.642 202.100 1.00 98.94  ? 493 TYR A CA  1 
ATOM   3706  C C   . TYR A 1 493 ? 144.600 128.482 202.266 1.00 98.94  ? 493 TYR A C   1 
ATOM   3707  O O   . TYR A 1 493 ? 144.696 129.711 202.345 1.00 98.94  ? 493 TYR A O   1 
ATOM   3708  C CB  . TYR A 1 493 ? 146.807 128.320 201.107 1.00 98.94  ? 493 TYR A CB  1 
ATOM   3709  C CG  . TYR A 1 493 ? 147.880 127.410 200.551 1.00 98.94  ? 493 TYR A CG  1 
ATOM   3710  C CD1 . TYR A 1 493 ? 149.067 127.199 201.238 1.00 98.94  ? 493 TYR A CD1 1 
ATOM   3711  C CD2 . TYR A 1 493 ? 147.711 126.776 199.325 1.00 98.94  ? 493 TYR A CD2 1 
ATOM   3712  C CE1 . TYR A 1 493 ? 150.050 126.370 200.727 1.00 98.94  ? 493 TYR A CE1 1 
ATOM   3713  C CE2 . TYR A 1 493 ? 148.688 125.947 198.808 1.00 98.94  ? 493 TYR A CE2 1 
ATOM   3714  C CZ  . TYR A 1 493 ? 149.854 125.748 199.511 1.00 98.94  ? 493 TYR A CZ  1 
ATOM   3715  O OH  . TYR A 1 493 ? 150.827 124.923 198.993 1.00 98.94  ? 493 TYR A OH  1 
ATOM   3716  N N   . ARG A 1 494 ? 143.423 127.848 202.306 1.00 100.19 ? 494 ARG A N   1 
ATOM   3717  C CA  . ARG A 1 494 ? 142.162 128.587 202.338 1.00 100.19 ? 494 ARG A CA  1 
ATOM   3718  C C   . ARG A 1 494 ? 142.068 129.503 203.555 1.00 100.19 ? 494 ARG A C   1 
ATOM   3719  O O   . ARG A 1 494 ? 141.821 130.708 203.420 1.00 100.19 ? 494 ARG A O   1 
ATOM   3720  C CB  . ARG A 1 494 ? 140.991 127.604 202.322 1.00 100.19 ? 494 ARG A CB  1 
ATOM   3721  C CG  . ARG A 1 494 ? 139.687 128.181 201.800 1.00 100.19 ? 494 ARG A CG  1 
ATOM   3722  C CD  . ARG A 1 494 ? 138.472 127.417 202.308 1.00 100.19 ? 494 ARG A CD  1 
ATOM   3723  N NE  . ARG A 1 494 ? 137.329 127.563 201.412 1.00 100.19 ? 494 ARG A NE  1 
ATOM   3724  C CZ  . ARG A 1 494 ? 136.484 128.585 201.422 1.00 100.19 ? 494 ARG A CZ  1 
ATOM   3725  N NH1 . ARG A 1 494 ? 136.613 129.580 202.283 1.00 100.19 ? 494 ARG A NH1 1 
ATOM   3726  N NH2 . ARG A 1 494 ? 135.488 128.612 200.540 1.00 100.19 ? 494 ARG A NH2 1 
ATOM   3727  N N   . ASP A 1 495 ? 142.264 128.949 204.754 1.00 103.96 ? 495 ASP A N   1 
ATOM   3728  C CA  . ASP A 1 495 ? 142.095 129.745 205.967 1.00 103.96 ? 495 ASP A CA  1 
ATOM   3729  C C   . ASP A 1 495 ? 143.160 130.828 206.076 1.00 103.96 ? 495 ASP A C   1 
ATOM   3730  O O   . ASP A 1 495 ? 142.862 131.957 206.481 1.00 103.96 ? 495 ASP A O   1 
ATOM   3731  C CB  . ASP A 1 495 ? 142.114 128.842 207.199 1.00 103.96 ? 495 ASP A CB  1 
ATOM   3732  C CG  . ASP A 1 495 ? 141.156 127.673 207.081 1.00 103.96 ? 495 ASP A CG  1 
ATOM   3733  O OD1 . ASP A 1 495 ? 139.948 127.913 206.877 1.00 103.96 ? 495 ASP A OD1 1 
ATOM   3734  O OD2 . ASP A 1 495 ? 141.609 126.516 207.203 1.00 103.96 ? 495 ASP A OD2 1 
ATOM   3735  N N   . GLU A 1 496 ? 144.406 130.503 205.726 1.00 103.16 ? 496 GLU A N   1 
ATOM   3736  C CA  . GLU A 1 496 ? 145.470 131.500 205.787 1.00 103.16 ? 496 GLU A CA  1 
ATOM   3737  C C   . GLU A 1 496 ? 145.206 132.648 204.820 1.00 103.16 ? 496 GLU A C   1 
ATOM   3738  O O   . GLU A 1 496 ? 145.381 133.822 205.175 1.00 103.16 ? 496 GLU A O   1 
ATOM   3739  C CB  . GLU A 1 496 ? 146.819 130.843 205.497 1.00 103.16 ? 496 GLU A CB  1 
ATOM   3740  C CG  . GLU A 1 496 ? 148.010 131.776 205.638 1.00 103.16 ? 496 GLU A CG  1 
ATOM   3741  C CD  . GLU A 1 496 ? 149.294 131.171 205.104 1.00 103.16 ? 496 GLU A CD  1 
ATOM   3742  O OE1 . GLU A 1 496 ? 150.219 131.939 204.770 1.00 103.16 ? 496 GLU A OE1 1 
ATOM   3743  O OE2 . GLU A 1 496 ? 149.380 129.927 205.024 1.00 103.16 ? 496 GLU A OE2 1 
ATOM   3744  N N   . ALA A 1 497 ? 144.769 132.333 203.597 1.00 102.40 ? 497 ALA A N   1 
ATOM   3745  C CA  . ALA A 1 497 ? 144.454 133.381 202.634 1.00 102.40 ? 497 ALA A CA  1 
ATOM   3746  C C   . ALA A 1 497 ? 143.278 134.227 203.101 1.00 102.40 ? 497 ALA A C   1 
ATOM   3747  O O   . ALA A 1 497 ? 143.295 135.454 202.950 1.00 102.40 ? 497 ALA A O   1 
ATOM   3748  C CB  . ALA A 1 497 ? 144.167 132.767 201.265 1.00 102.40 ? 497 ALA A CB  1 
ATOM   3749  N N   . LEU A 1 498 ? 142.247 133.595 203.670 1.00 104.08 ? 498 LEU A N   1 
ATOM   3750  C CA  . LEU A 1 498 ? 141.110 134.361 204.172 1.00 104.08 ? 498 LEU A CA  1 
ATOM   3751  C C   . LEU A 1 498 ? 141.527 135.284 205.309 1.00 104.08 ? 498 LEU A C   1 
ATOM   3752  O O   . LEU A 1 498 ? 141.076 136.433 205.384 1.00 104.08 ? 498 LEU A O   1 
ATOM   3753  C CB  . LEU A 1 498 ? 139.993 133.423 204.629 1.00 104.08 ? 498 LEU A CB  1 
ATOM   3754  C CG  . LEU A 1 498 ? 139.250 132.650 203.540 1.00 104.08 ? 498 LEU A CG  1 
ATOM   3755  C CD1 . LEU A 1 498 ? 138.318 131.626 204.166 1.00 104.08 ? 498 LEU A CD1 1 
ATOM   3756  C CD2 . LEU A 1 498 ? 138.484 133.599 202.633 1.00 104.08 ? 498 LEU A CD2 1 
ATOM   3757  N N   . ASN A 1 499 ? 142.383 134.797 206.209 1.00 104.65 ? 499 ASN A N   1 
ATOM   3758  C CA  . ASN A 1 499 ? 142.856 135.632 207.307 1.00 104.65 ? 499 ASN A CA  1 
ATOM   3759  C C   . ASN A 1 499 ? 143.687 136.801 206.794 1.00 104.65 ? 499 ASN A C   1 
ATOM   3760  O O   . ASN A 1 499 ? 143.578 137.920 207.309 1.00 104.65 ? 499 ASN A O   1 
ATOM   3761  C CB  . ASN A 1 499 ? 143.661 134.790 208.296 1.00 104.65 ? 499 ASN A CB  1 
ATOM   3762  C CG  . ASN A 1 499 ? 142.781 133.908 209.159 1.00 104.65 ? 499 ASN A CG  1 
ATOM   3763  O OD1 . ASN A 1 499 ? 141.600 134.194 209.356 1.00 104.65 ? 499 ASN A OD1 1 
ATOM   3764  N ND2 . ASN A 1 499 ? 143.353 132.828 209.678 1.00 104.65 ? 499 ASN A ND2 1 
ATOM   3765  N N   . ASN A 1 500 ? 144.527 136.564 205.783 1.00 102.03 ? 500 ASN A N   1 
ATOM   3766  C CA  . ASN A 1 500 ? 145.348 137.644 205.246 1.00 102.03 ? 500 ASN A CA  1 
ATOM   3767  C C   . ASN A 1 500 ? 144.505 138.680 204.508 1.00 102.03 ? 500 ASN A C   1 
ATOM   3768  O O   . ASN A 1 500 ? 144.753 139.886 204.628 1.00 102.03 ? 500 ASN A O   1 
ATOM   3769  C CB  . ASN A 1 500 ? 146.426 137.075 204.325 1.00 102.03 ? 500 ASN A CB  1 
ATOM   3770  C CG  . ASN A 1 500 ? 147.568 136.438 205.091 1.00 102.03 ? 500 ASN A CG  1 
ATOM   3771  O OD1 . ASN A 1 500 ? 147.972 135.312 204.803 1.00 102.03 ? 500 ASN A OD1 1 
ATOM   3772  N ND2 . ASN A 1 500 ? 148.096 137.159 206.073 1.00 102.03 ? 500 ASN A ND2 1 
ATOM   3773  N N   . ARG A 1 501 ? 143.507 138.232 203.741 1.00 100.71 ? 501 ARG A N   1 
ATOM   3774  C CA  . ARG A 1 501 ? 142.711 139.165 202.946 1.00 100.71 ? 501 ARG A CA  1 
ATOM   3775  C C   . ARG A 1 501 ? 141.829 140.044 203.824 1.00 100.71 ? 501 ARG A C   1 
ATOM   3776  O O   . ARG A 1 501 ? 141.708 141.250 203.580 1.00 100.71 ? 501 ARG A O   1 
ATOM   3777  C CB  . ARG A 1 501 ? 141.855 138.403 201.934 1.00 100.71 ? 501 ARG A CB  1 
ATOM   3778  C CG  . ARG A 1 501 ? 142.647 137.709 200.843 1.00 100.71 ? 501 ARG A CG  1 
ATOM   3779  C CD  . ARG A 1 501 ? 141.740 136.941 199.896 1.00 100.71 ? 501 ARG A CD  1 
ATOM   3780  N NE  . ARG A 1 501 ? 140.870 137.825 199.131 1.00 100.71 ? 501 ARG A NE  1 
ATOM   3781  C CZ  . ARG A 1 501 ? 139.883 137.411 198.349 1.00 100.71 ? 501 ARG A CZ  1 
ATOM   3782  N NH1 . ARG A 1 501 ? 139.615 136.124 198.198 1.00 100.71 ? 501 ARG A NH1 1 
ATOM   3783  N NH2 . ARG A 1 501 ? 139.146 138.309 197.702 1.00 100.71 ? 501 ARG A NH2 1 
ATOM   3784  N N   . PHE A 1 502 ? 141.206 139.463 204.844 1.00 103.14 ? 502 PHE A N   1 
ATOM   3785  C CA  . PHE A 1 502 ? 140.252 140.198 205.665 1.00 103.14 ? 502 PHE A CA  1 
ATOM   3786  C C   . PHE A 1 502 ? 140.820 140.489 207.049 1.00 103.14 ? 502 PHE A C   1 
ATOM   3787  O O   . PHE A 1 502 ? 141.103 141.639 207.385 1.00 103.14 ? 502 PHE A O   1 
ATOM   3788  C CB  . PHE A 1 502 ? 138.943 139.415 205.781 1.00 103.14 ? 502 PHE A CB  1 
ATOM   3789  C CG  . PHE A 1 502 ? 138.293 139.124 204.459 1.00 103.14 ? 502 PHE A CG  1 
ATOM   3790  C CD1 . PHE A 1 502 ? 138.225 140.097 203.476 1.00 103.14 ? 502 PHE A CD1 1 
ATOM   3791  C CD2 . PHE A 1 502 ? 137.758 137.874 204.194 1.00 103.14 ? 502 PHE A CD2 1 
ATOM   3792  C CE1 . PHE A 1 502 ? 137.631 139.831 202.256 1.00 103.14 ? 502 PHE A CE1 1 
ATOM   3793  C CE2 . PHE A 1 502 ? 137.163 137.602 202.977 1.00 103.14 ? 502 PHE A CE2 1 
ATOM   3794  C CZ  . PHE A 1 502 ? 137.099 138.582 202.007 1.00 103.14 ? 502 PHE A CZ  1 
ATOM   3795  N N   . THR B 1 12  ? 126.568 154.744 200.405 1.00 94.05  ? 12  THR B N   1 
ATOM   3796  C CA  . THR B 1 12  ? 126.741 153.938 199.203 1.00 94.05  ? 12  THR B CA  1 
ATOM   3797  C C   . THR B 1 12  ? 126.474 154.757 197.944 1.00 94.05  ? 12  THR B C   1 
ATOM   3798  O O   . THR B 1 12  ? 125.758 155.757 197.983 1.00 94.05  ? 12  THR B O   1 
ATOM   3799  C CB  . THR B 1 12  ? 125.813 152.708 199.208 1.00 94.05  ? 12  THR B CB  1 
ATOM   3800  O OG1 . THR B 1 12  ? 124.446 153.136 199.238 1.00 94.05  ? 12  THR B OG1 1 
ATOM   3801  C CG2 . THR B 1 12  ? 126.094 151.833 200.419 1.00 94.05  ? 12  THR B CG2 1 
ATOM   3802  N N   . ALA B 1 13  ? 127.054 154.323 196.826 1.00 90.57  ? 13  ALA B N   1 
ATOM   3803  C CA  . ALA B 1 13  ? 126.892 155.003 195.551 1.00 90.57  ? 13  ALA B CA  1 
ATOM   3804  C C   . ALA B 1 13  ? 126.749 153.967 194.446 1.00 90.57  ? 13  ALA B C   1 
ATOM   3805  O O   . ALA B 1 13  ? 127.137 152.807 194.601 1.00 90.57  ? 13  ALA B O   1 
ATOM   3806  C CB  . ALA B 1 13  ? 128.071 155.939 195.253 1.00 90.57  ? 13  ALA B CB  1 
ATOM   3807  N N   . THR B 1 14  ? 126.182 154.401 193.324 1.00 85.86  ? 14  THR B N   1 
ATOM   3808  C CA  . THR B 1 14  ? 125.944 153.546 192.169 1.00 85.86  ? 14  THR B CA  1 
ATOM   3809  C C   . THR B 1 14  ? 126.625 154.138 190.943 1.00 85.86  ? 14  THR B C   1 
ATOM   3810  O O   . THR B 1 14  ? 126.609 155.356 190.743 1.00 85.86  ? 14  THR B O   1 
ATOM   3811  C CB  . THR B 1 14  ? 124.442 153.381 191.902 1.00 85.86  ? 14  THR B CB  1 
ATOM   3812  O OG1 . THR B 1 14  ? 123.769 153.065 193.127 1.00 85.86  ? 14  THR B OG1 1 
ATOM   3813  C CG2 . THR B 1 14  ? 124.194 152.273 190.893 1.00 85.86  ? 14  THR B CG2 1 
ATOM   3814  N N   . LEU B 1 15  ? 127.234 153.275 190.133 1.00 79.22  ? 15  LEU B N   1 
ATOM   3815  C CA  . LEU B 1 15  ? 127.881 153.680 188.892 1.00 79.22  ? 15  LEU B CA  1 
ATOM   3816  C C   . LEU B 1 15  ? 127.436 152.750 187.773 1.00 79.22  ? 15  LEU B C   1 
ATOM   3817  O O   . LEU B 1 15  ? 127.491 151.526 187.923 1.00 79.22  ? 15  LEU B O   1 
ATOM   3818  C CB  . LEU B 1 15  ? 129.407 153.657 189.028 1.00 79.22  ? 15  LEU B CB  1 
ATOM   3819  C CG  . LEU B 1 15  ? 130.201 154.229 187.851 1.00 79.22  ? 15  LEU B CG  1 
ATOM   3820  C CD1 . LEU B 1 15  ? 129.975 155.726 187.729 1.00 79.22  ? 15  LEU B CD1 1 
ATOM   3821  C CD2 . LEU B 1 15  ? 131.682 153.921 187.999 1.00 79.22  ? 15  LEU B CD2 1 
ATOM   3822  N N   . CYS B 1 16  ? 127.003 153.329 186.657 1.00 75.48  ? 16  CYS B N   1 
ATOM   3823  C CA  . CYS B 1 16  ? 126.498 152.570 185.523 1.00 75.48  ? 16  CYS B CA  1 
ATOM   3824  C C   . CYS B 1 16  ? 127.270 152.920 184.259 1.00 75.48  ? 16  CYS B C   1 
ATOM   3825  O O   . CYS B 1 16  ? 127.816 154.019 184.126 1.00 75.48  ? 16  CYS B O   1 
ATOM   3826  C CB  . CYS B 1 16  ? 125.004 152.829 185.298 1.00 75.48  ? 16  CYS B CB  1 
ATOM   3827  S SG  . CYS B 1 16  ? 123.924 152.110 186.548 1.00 75.48  ? 16  CYS B SG  1 
ATOM   3828  N N   . LEU B 1 17  ? 127.309 151.967 183.332 1.00 69.94  ? 17  LEU B N   1 
ATOM   3829  C CA  . LEU B 1 17  ? 127.943 152.140 182.034 1.00 69.94  ? 17  LEU B CA  1 
ATOM   3830  C C   . LEU B 1 17  ? 126.925 151.856 180.939 1.00 69.94  ? 17  LEU B C   1 
ATOM   3831  O O   . LEU B 1 17  ? 126.118 150.929 181.056 1.00 69.94  ? 17  LEU B O   1 
ATOM   3832  C CB  . LEU B 1 17  ? 129.154 151.215 181.877 1.00 69.94  ? 17  LEU B CB  1 
ATOM   3833  C CG  . LEU B 1 17  ? 130.439 151.623 182.600 1.00 69.94  ? 17  LEU B CG  1 
ATOM   3834  C CD1 . LEU B 1 17  ? 130.408 151.190 184.056 1.00 69.94  ? 17  LEU B CD1 1 
ATOM   3835  C CD2 . LEU B 1 17  ? 131.650 151.043 181.896 1.00 69.94  ? 17  LEU B CD2 1 
ATOM   3836  N N   . GLY B 1 18  ? 126.965 152.653 179.875 1.00 68.39  ? 18  GLY B N   1 
ATOM   3837  C CA  . GLY B 1 18  ? 126.006 152.493 178.801 1.00 68.39  ? 18  GLY B CA  1 
ATOM   3838  C C   . GLY B 1 18  ? 126.476 153.182 177.539 1.00 68.39  ? 18  GLY B C   1 
ATOM   3839  O O   . GLY B 1 18  ? 127.541 153.800 177.499 1.00 68.39  ? 18  GLY B O   1 
ATOM   3840  N N   . HIS B 1 19  ? 125.653 153.067 176.500 1.00 65.04  ? 19  HIS B N   1 
ATOM   3841  C CA  . HIS B 1 19  ? 125.959 153.627 175.193 1.00 65.04  ? 19  HIS B CA  1 
ATOM   3842  C C   . HIS B 1 19  ? 124.748 154.393 174.680 1.00 65.04  ? 19  HIS B C   1 
ATOM   3843  O O   . HIS B 1 19  ? 123.645 154.293 175.222 1.00 65.04  ? 19  HIS B O   1 
ATOM   3844  C CB  . HIS B 1 19  ? 126.377 152.535 174.200 1.00 65.04  ? 19  HIS B CB  1 
ATOM   3845  C CG  . HIS B 1 19  ? 125.407 151.399 174.106 1.00 65.04  ? 19  HIS B CG  1 
ATOM   3846  N ND1 . HIS B 1 19  ? 124.206 151.498 173.438 1.00 65.04  ? 19  HIS B ND1 1 
ATOM   3847  C CD2 . HIS B 1 19  ? 125.461 150.138 174.597 1.00 65.04  ? 19  HIS B CD2 1 
ATOM   3848  C CE1 . HIS B 1 19  ? 123.562 150.348 173.522 1.00 65.04  ? 19  HIS B CE1 1 
ATOM   3849  N NE2 . HIS B 1 19  ? 124.302 149.506 174.220 1.00 65.04  ? 19  HIS B NE2 1 
ATOM   3850  N N   . HIS B 1 20  ? 124.967 155.166 173.621 1.00 65.10  ? 20  HIS B N   1 
ATOM   3851  C CA  . HIS B 1 20  ? 123.935 156.040 173.087 1.00 65.10  ? 20  HIS B CA  1 
ATOM   3852  C C   . HIS B 1 20  ? 123.031 155.289 172.111 1.00 65.10  ? 20  HIS B C   1 
ATOM   3853  O O   . HIS B 1 20  ? 123.330 154.180 171.661 1.00 65.10  ? 20  HIS B O   1 
ATOM   3854  C CB  . HIS B 1 20  ? 124.566 157.249 172.397 1.00 65.10  ? 20  HIS B CB  1 
ATOM   3855  C CG  . HIS B 1 20  ? 125.073 156.964 171.018 1.00 65.10  ? 20  HIS B CG  1 
ATOM   3856  N ND1 . HIS B 1 20  ? 126.316 156.420 170.779 1.00 65.10  ? 20  HIS B ND1 1 
ATOM   3857  C CD2 . HIS B 1 20  ? 124.509 157.158 169.802 1.00 65.10  ? 20  HIS B CD2 1 
ATOM   3858  C CE1 . HIS B 1 20  ? 126.494 156.285 169.477 1.00 65.10  ? 20  HIS B CE1 1 
ATOM   3859  N NE2 . HIS B 1 20  ? 125.412 156.725 168.862 1.00 65.10  ? 20  HIS B NE2 1 
ATOM   3860  N N   . SER B 1 21  ? 121.903 155.916 171.790 1.00 66.81  ? 21  SER B N   1 
ATOM   3861  C CA  . SER B 1 21  ? 120.986 155.404 170.783 1.00 66.81  ? 21  SER B CA  1 
ATOM   3862  C C   . SER B 1 21  ? 120.277 156.584 170.136 1.00 66.81  ? 21  SER B C   1 
ATOM   3863  O O   . SER B 1 21  ? 120.230 157.684 170.691 1.00 66.81  ? 21  SER B O   1 
ATOM   3864  C CB  . SER B 1 21  ? 119.974 154.420 171.380 1.00 66.81  ? 21  SER B CB  1 
ATOM   3865  O OG  . SER B 1 21  ? 119.085 155.075 172.264 1.00 66.81  ? 21  SER B OG  1 
ATOM   3866  N N   . VAL B 1 22  ? 119.726 156.344 168.952 1.00 63.87  ? 22  VAL B N   1 
ATOM   3867  C CA  . VAL B 1 22  ? 119.075 157.404 168.185 1.00 63.87  ? 22  VAL B CA  1 
ATOM   3868  C C   . VAL B 1 22  ? 117.594 157.082 168.028 1.00 63.87  ? 22  VAL B C   1 
ATOM   3869  O O   . VAL B 1 22  ? 117.213 155.903 168.026 1.00 63.87  ? 22  VAL B O   1 
ATOM   3870  C CB  . VAL B 1 22  ? 119.754 157.594 166.819 1.00 63.87  ? 22  VAL B CB  1 
ATOM   3871  C CG1 . VAL B 1 22  ? 121.170 158.114 167.004 1.00 63.87  ? 22  VAL B CG1 1 
ATOM   3872  C CG2 . VAL B 1 22  ? 119.770 156.286 166.049 1.00 63.87  ? 22  VAL B CG2 1 
ATOM   3873  N N   . PRO B 1 23  ? 116.726 158.092 167.916 1.00 65.13  ? 23  PRO B N   1 
ATOM   3874  C CA  . PRO B 1 23  ? 115.293 157.813 167.728 1.00 65.13  ? 23  PRO B CA  1 
ATOM   3875  C C   . PRO B 1 23  ? 114.985 157.004 166.482 1.00 65.13  ? 23  PRO B C   1 
ATOM   3876  O O   . PRO B 1 23  ? 114.052 156.191 166.500 1.00 65.13  ? 23  PRO B O   1 
ATOM   3877  C CB  . PRO B 1 23  ? 114.679 159.222 167.642 1.00 65.13  ? 23  PRO B CB  1 
ATOM   3878  C CG  . PRO B 1 23  ? 115.881 160.156 167.484 1.00 65.13  ? 23  PRO B CG  1 
ATOM   3879  C CD  . PRO B 1 23  ? 116.926 159.496 168.296 1.00 65.13  ? 23  PRO B CD  1 
ATOM   3880  N N   . ASN B 1 24  ? 115.730 157.201 165.396 1.00 62.86  ? 24  ASN B N   1 
ATOM   3881  C CA  . ASN B 1 24  ? 115.468 156.515 164.137 1.00 62.86  ? 24  ASN B CA  1 
ATOM   3882  C C   . ASN B 1 24  ? 116.726 155.791 163.683 1.00 62.86  ? 24  ASN B C   1 
ATOM   3883  O O   . ASN B 1 24  ? 117.781 156.411 163.518 1.00 62.86  ? 24  ASN B O   1 
ATOM   3884  C CB  . ASN B 1 24  ? 114.984 157.495 163.064 1.00 62.86  ? 24  ASN B CB  1 
ATOM   3885  C CG  . ASN B 1 24  ? 115.957 158.633 162.828 1.00 62.86  ? 24  ASN B CG  1 
ATOM   3886  O OD1 . ASN B 1 24  ? 116.774 158.955 163.690 1.00 62.86  ? 24  ASN B OD1 1 
ATOM   3887  N ND2 . ASN B 1 24  ? 115.874 159.245 161.654 1.00 62.86  ? 24  ASN B ND2 1 
ATOM   3888  N N   . GLY B 1 25  ? 116.611 154.478 163.483 1.00 56.38  ? 25  GLY B N   1 
ATOM   3889  C CA  . GLY B 1 25  ? 117.711 153.657 163.039 1.00 56.38  ? 25  GLY B CA  1 
ATOM   3890  C C   . GLY B 1 25  ? 117.528 153.166 161.612 1.00 56.38  ? 25  GLY B C   1 
ATOM   3891  O O   . GLY B 1 25  ? 116.533 153.430 160.942 1.00 56.38  ? 25  GLY B O   1 
ATOM   3892  N N   . THR B 1 26  ? 118.537 152.432 161.157 1.00 49.97  ? 26  THR B N   1 
ATOM   3893  C CA  . THR B 1 26  ? 118.565 151.877 159.813 1.00 49.97  ? 26  THR B CA  1 
ATOM   3894  C C   . THR B 1 26  ? 118.958 150.409 159.884 1.00 49.97  ? 26  THR B C   1 
ATOM   3895  O O   . THR B 1 26  ? 119.752 150.010 160.740 1.00 49.97  ? 26  THR B O   1 
ATOM   3896  C CB  . THR B 1 26  ? 119.532 152.664 158.911 1.00 49.97  ? 26  THR B CB  1 
ATOM   3897  O OG1 . THR B 1 26  ? 119.516 152.121 157.585 1.00 49.97  ? 26  THR B OG1 1 
ATOM   3898  C CG2 . THR B 1 26  ? 120.943 152.639 159.468 1.00 49.97  ? 26  THR B CG2 1 
ATOM   3899  N N   . ILE B 1 27  ? 118.390 149.609 158.988 1.00 47.13  ? 27  ILE B N   1 
ATOM   3900  C CA  . ILE B 1 27  ? 118.561 148.162 159.000 1.00 47.13  ? 27  ILE B CA  1 
ATOM   3901  C C   . ILE B 1 27  ? 119.661 147.784 158.019 1.00 47.13  ? 27  ILE B C   1 
ATOM   3902  O O   . ILE B 1 27  ? 119.660 148.236 156.868 1.00 47.13  ? 27  ILE B O   1 
ATOM   3903  C CB  . ILE B 1 27  ? 117.249 147.443 158.647 1.00 47.13  ? 27  ILE B CB  1 
ATOM   3904  C CG1 . ILE B 1 27  ? 116.130 147.881 159.591 1.00 47.13  ? 27  ILE B CG1 1 
ATOM   3905  C CG2 . ILE B 1 27  ? 117.444 145.945 158.735 1.00 47.13  ? 27  ILE B CG2 1 
ATOM   3906  C CD1 . ILE B 1 27  ? 116.127 147.158 160.919 1.00 47.13  ? 27  ILE B CD1 1 
ATOM   3907  N N   . VAL B 1 28  ? 120.596 146.949 158.472 1.00 44.74  ? 28  VAL B N   1 
ATOM   3908  C CA  . VAL B 1 28  ? 121.662 146.425 157.632 1.00 44.74  ? 28  VAL B CA  1 
ATOM   3909  C C   . VAL B 1 28  ? 121.643 144.904 157.730 1.00 44.74  ? 28  VAL B C   1 
ATOM   3910  O O   . VAL B 1 28  ? 120.885 144.318 158.503 1.00 44.74  ? 28  VAL B O   1 
ATOM   3911  C CB  . VAL B 1 28  ? 123.048 146.978 158.024 1.00 44.74  ? 28  VAL B CB  1 
ATOM   3912  C CG1 . VAL B 1 28  ? 123.074 148.490 157.885 1.00 44.74  ? 28  VAL B CG1 1 
ATOM   3913  C CG2 . VAL B 1 28  ? 123.411 146.556 159.431 1.00 44.74  ? 28  VAL B CG2 1 
ATOM   3914  N N   . LYS B 1 29  ? 122.492 144.268 156.928 1.00 42.03  ? 29  LYS B N   1 
ATOM   3915  C CA  . LYS B 1 29  ? 122.581 142.816 156.858 1.00 42.03  ? 29  LYS B CA  1 
ATOM   3916  C C   . LYS B 1 29  ? 124.000 142.380 157.189 1.00 42.03  ? 29  LYS B C   1 
ATOM   3917  O O   . LYS B 1 29  ? 124.965 142.937 156.657 1.00 42.03  ? 29  LYS B O   1 
ATOM   3918  C CB  . LYS B 1 29  ? 122.181 142.310 155.470 1.00 42.03  ? 29  LYS B CB  1 
ATOM   3919  C CG  . LYS B 1 29  ? 122.235 140.801 155.321 1.00 42.03  ? 29  LYS B CG  1 
ATOM   3920  C CD  . LYS B 1 29  ? 121.465 140.338 154.098 1.00 42.03  ? 29  LYS B CD  1 
ATOM   3921  C CE  . LYS B 1 29  ? 122.177 140.735 152.817 1.00 42.03  ? 29  LYS B CE  1 
ATOM   3922  N NZ  . LYS B 1 29  ? 121.477 140.231 151.604 1.00 42.03  ? 29  LYS B NZ  1 
ATOM   3923  N N   . THR B 1 30  ? 124.122 141.387 158.062 1.00 41.53  ? 30  THR B N   1 
ATOM   3924  C CA  . THR B 1 30  ? 125.409 140.848 158.479 1.00 41.53  ? 30  THR B CA  1 
ATOM   3925  C C   . THR B 1 30  ? 125.494 139.374 158.082 1.00 41.53  ? 30  THR B C   1 
ATOM   3926  O O   . THR B 1 30  ? 124.612 138.837 157.407 1.00 41.53  ? 30  THR B O   1 
ATOM   3927  C CB  . THR B 1 30  ? 125.612 141.035 159.985 1.00 41.53  ? 30  THR B CB  1 
ATOM   3928  O OG1 . THR B 1 30  ? 124.709 140.185 160.701 1.00 41.53  ? 30  THR B OG1 1 
ATOM   3929  C CG2 . THR B 1 30  ? 125.358 142.477 160.385 1.00 41.53  ? 30  THR B CG2 1 
ATOM   3930  N N   . ILE B 1 31  ? 126.580 138.724 158.504 1.00 41.58  ? 31  ILE B N   1 
ATOM   3931  C CA  . ILE B 1 31  ? 126.769 137.309 158.200 1.00 41.58  ? 31  ILE B CA  1 
ATOM   3932  C C   . ILE B 1 31  ? 125.784 136.452 158.987 1.00 41.58  ? 31  ILE B C   1 
ATOM   3933  O O   . ILE B 1 31  ? 125.224 135.483 158.460 1.00 41.58  ? 31  ILE B O   1 
ATOM   3934  C CB  . ILE B 1 31  ? 128.229 136.899 158.475 1.00 41.58  ? 31  ILE B CB  1 
ATOM   3935  C CG1 . ILE B 1 31  ? 129.148 137.404 157.361 1.00 41.58  ? 31  ILE B CG1 1 
ATOM   3936  C CG2 . ILE B 1 31  ? 128.352 135.390 158.626 1.00 41.58  ? 31  ILE B CG2 1 
ATOM   3937  C CD1 . ILE B 1 31  ? 128.976 136.676 156.047 1.00 41.58  ? 31  ILE B CD1 1 
ATOM   3938  N N   . THR B 1 32  ? 125.546 136.795 160.254 1.00 45.09  ? 32  THR B N   1 
ATOM   3939  C CA  . THR B 1 32  ? 124.729 135.966 161.130 1.00 45.09  ? 32  THR B CA  1 
ATOM   3940  C C   . THR B 1 32  ? 123.316 136.492 161.343 1.00 45.09  ? 32  THR B C   1 
ATOM   3941  O O   . THR B 1 32  ? 122.512 135.804 161.980 1.00 45.09  ? 32  THR B O   1 
ATOM   3942  C CB  . THR B 1 32  ? 125.404 135.809 162.499 1.00 45.09  ? 32  THR B CB  1 
ATOM   3943  O OG1 . THR B 1 32  ? 125.615 137.101 163.079 1.00 45.09  ? 32  THR B OG1 1 
ATOM   3944  C CG2 . THR B 1 32  ? 126.741 135.097 162.357 1.00 45.09  ? 32  THR B CG2 1 
ATOM   3945  N N   . ASP B 1 33  ? 122.989 137.679 160.840 1.00 47.24  ? 33  ASP B N   1 
ATOM   3946  C CA  . ASP B 1 33  ? 121.664 138.259 161.008 1.00 47.24  ? 33  ASP B CA  1 
ATOM   3947  C C   . ASP B 1 33  ? 121.110 138.708 159.664 1.00 47.24  ? 33  ASP B C   1 
ATOM   3948  O O   . ASP B 1 33  ? 121.818 139.327 158.864 1.00 47.24  ? 33  ASP B O   1 
ATOM   3949  C CB  . ASP B 1 33  ? 121.694 139.445 161.978 1.00 47.24  ? 33  ASP B CB  1 
ATOM   3950  C CG  . ASP B 1 33  ? 121.975 139.024 163.406 1.00 47.24  ? 33  ASP B CG  1 
ATOM   3951  O OD1 . ASP B 1 33  ? 121.612 137.887 163.775 1.00 47.24  ? 33  ASP B OD1 1 
ATOM   3952  O OD2 . ASP B 1 33  ? 122.558 139.830 164.162 1.00 47.24  ? 33  ASP B OD2 1 
ATOM   3953  N N   . ASP B 1 34  ? 119.838 138.385 159.421 1.00 49.46  ? 34  ASP B N   1 
ATOM   3954  C CA  . ASP B 1 34  ? 119.176 138.831 158.199 1.00 49.46  ? 34  ASP B CA  1 
ATOM   3955  C C   . ASP B 1 34  ? 118.900 140.329 158.239 1.00 49.46  ? 34  ASP B C   1 
ATOM   3956  O O   . ASP B 1 34  ? 119.211 141.054 157.287 1.00 49.46  ? 34  ASP B O   1 
ATOM   3957  C CB  . ASP B 1 34  ? 117.871 138.056 158.000 1.00 49.46  ? 34  ASP B CB  1 
ATOM   3958  C CG  . ASP B 1 34  ? 118.058 136.786 157.193 1.00 49.46  ? 34  ASP B CG  1 
ATOM   3959  O OD1 . ASP B 1 34  ? 118.869 136.789 156.244 1.00 49.46  ? 34  ASP B OD1 1 
ATOM   3960  O OD2 . ASP B 1 34  ? 117.386 135.781 157.506 1.00 49.46  ? 34  ASP B OD2 1 
ATOM   3961  N N   . GLN B 1 35  ? 118.329 140.811 159.341 1.00 50.92  ? 35  GLN B N   1 
ATOM   3962  C CA  . GLN B 1 35  ? 117.891 142.197 159.462 1.00 50.92  ? 35  GLN B CA  1 
ATOM   3963  C C   . GLN B 1 35  ? 118.268 142.692 160.849 1.00 50.92  ? 35  GLN B C   1 
ATOM   3964  O O   . GLN B 1 35  ? 117.716 142.217 161.845 1.00 50.92  ? 35  GLN B O   1 
ATOM   3965  C CB  . GLN B 1 35  ? 116.376 142.309 159.250 1.00 50.92  ? 35  GLN B CB  1 
ATOM   3966  C CG  . GLN B 1 35  ? 115.881 141.940 157.850 1.00 50.92  ? 35  GLN B CG  1 
ATOM   3967  C CD  . GLN B 1 35  ? 116.417 142.840 156.756 1.00 50.92  ? 35  GLN B CD  1 
ATOM   3968  O OE1 . GLN B 1 35  ? 116.035 144.007 156.650 1.00 50.92  ? 35  GLN B OE1 1 
ATOM   3969  N NE2 . GLN B 1 35  ? 117.341 142.314 155.959 1.00 50.92  ? 35  GLN B NE2 1 
ATOM   3970  N N   . ILE B 1 36  ? 119.196 143.643 160.919 1.00 48.63  ? 36  ILE B N   1 
ATOM   3971  C CA  . ILE B 1 36  ? 119.660 144.193 162.189 1.00 48.63  ? 36  ILE B CA  1 
ATOM   3972  C C   . ILE B 1 36  ? 119.703 145.712 162.086 1.00 48.63  ? 36  ILE B C   1 
ATOM   3973  O O   . ILE B 1 36  ? 120.152 146.267 161.077 1.00 48.63  ? 36  ILE B O   1 
ATOM   3974  C CB  . ILE B 1 36  ? 121.036 143.614 162.591 1.00 48.63  ? 36  ILE B CB  1 
ATOM   3975  C CG1 . ILE B 1 36  ? 121.493 144.188 163.934 1.00 48.63  ? 36  ILE B CG1 1 
ATOM   3976  C CG2 . ILE B 1 36  ? 122.071 143.837 161.500 1.00 48.63  ? 36  ILE B CG2 1 
ATOM   3977  C CD1 . ILE B 1 36  ? 122.681 143.476 164.528 1.00 48.63  ? 36  ILE B CD1 1 
ATOM   3978  N N   . GLU B 1 37  ? 119.234 146.383 163.134 1.00 51.65  ? 37  GLU B N   1 
ATOM   3979  C CA  . GLU B 1 37  ? 119.117 147.836 163.159 1.00 51.65  ? 37  GLU B CA  1 
ATOM   3980  C C   . GLU B 1 37  ? 120.353 148.448 163.804 1.00 51.65  ? 37  GLU B C   1 
ATOM   3981  O O   . GLU B 1 37  ? 120.774 148.017 164.882 1.00 51.65  ? 37  GLU B O   1 
ATOM   3982  C CB  . GLU B 1 37  ? 117.859 148.259 163.917 1.00 51.65  ? 37  GLU B CB  1 
ATOM   3983  C CG  . GLU B 1 37  ? 117.412 149.684 163.653 1.00 51.65  ? 37  GLU B CG  1 
ATOM   3984  C CD  . GLU B 1 37  ? 116.353 150.143 164.633 1.00 51.65  ? 37  GLU B CD  1 
ATOM   3985  O OE1 . GLU B 1 37  ? 115.376 149.395 164.842 1.00 51.65  ? 37  GLU B OE1 1 
ATOM   3986  O OE2 . GLU B 1 37  ? 116.498 151.248 165.197 1.00 51.65  ? 37  GLU B OE2 1 
ATOM   3987  N N   . VAL B 1 38  ? 120.928 149.451 163.142 1.00 50.50  ? 38  VAL B N   1 
ATOM   3988  C CA  . VAL B 1 38  ? 122.099 150.159 163.638 1.00 50.50  ? 38  VAL B CA  1 
ATOM   3989  C C   . VAL B 1 38  ? 121.774 151.648 163.719 1.00 50.50  ? 38  VAL B C   1 
ATOM   3990  O O   . VAL B 1 38  ? 120.705 152.098 163.310 1.00 50.50  ? 38  VAL B O   1 
ATOM   3991  C CB  . VAL B 1 38  ? 123.347 149.915 162.767 1.00 50.50  ? 38  VAL B CB  1 
ATOM   3992  C CG1 . VAL B 1 38  ? 123.786 148.464 162.866 1.00 50.50  ? 38  VAL B CG1 1 
ATOM   3993  C CG2 . VAL B 1 38  ? 123.071 150.295 161.324 1.00 50.50  ? 38  VAL B CG2 1 
ATOM   3994  N N   . THR B 1 39  ? 122.721 152.413 164.265 1.00 51.88  ? 39  THR B N   1 
ATOM   3995  C CA  . THR B 1 39  ? 122.502 153.841 164.465 1.00 51.88  ? 39  THR B CA  1 
ATOM   3996  C C   . THR B 1 39  ? 122.825 154.678 163.233 1.00 51.88  ? 39  THR B C   1 
ATOM   3997  O O   . THR B 1 39  ? 122.388 155.831 163.159 1.00 51.88  ? 39  THR B O   1 
ATOM   3998  C CB  . THR B 1 39  ? 123.335 154.350 165.646 1.00 51.88  ? 39  THR B CB  1 
ATOM   3999  O OG1 . THR B 1 39  ? 124.728 154.226 165.341 1.00 51.88  ? 39  THR B OG1 1 
ATOM   4000  C CG2 . THR B 1 39  ? 123.028 153.551 166.900 1.00 51.88  ? 39  THR B CG2 1 
ATOM   4001  N N   . ASN B 1 40  ? 123.563 154.133 162.269 1.00 48.92  ? 40  ASN B N   1 
ATOM   4002  C CA  . ASN B 1 40  ? 123.990 154.908 161.112 1.00 48.92  ? 40  ASN B CA  1 
ATOM   4003  C C   . ASN B 1 40  ? 124.494 153.956 160.036 1.00 48.92  ? 40  ASN B C   1 
ATOM   4004  O O   . ASN B 1 40  ? 125.062 152.905 160.341 1.00 48.92  ? 40  ASN B O   1 
ATOM   4005  C CB  . ASN B 1 40  ? 125.085 155.912 161.494 1.00 48.92  ? 40  ASN B CB  1 
ATOM   4006  C CG  . ASN B 1 40  ? 125.205 157.054 160.507 1.00 48.92  ? 40  ASN B CG  1 
ATOM   4007  O OD1 . ASN B 1 40  ? 124.258 157.372 159.789 1.00 48.92  ? 40  ASN B OD1 1 
ATOM   4008  N ND2 . ASN B 1 40  ? 126.377 157.679 160.469 1.00 48.92  ? 40  ASN B ND2 1 
ATOM   4009  N N   . ALA B 1 41  ? 124.277 154.337 158.778 1.00 41.53  ? 41  ALA B N   1 
ATOM   4010  C CA  . ALA B 1 41  ? 124.748 153.551 157.645 1.00 41.53  ? 41  ALA B CA  1 
ATOM   4011  C C   . ALA B 1 41  ? 124.871 154.456 156.429 1.00 41.53  ? 41  ALA B C   1 
ATOM   4012  O O   . ALA B 1 41  ? 124.331 155.565 156.400 1.00 41.53  ? 41  ALA B O   1 
ATOM   4013  C CB  . ALA B 1 41  ? 123.816 152.374 157.344 1.00 41.53  ? 41  ALA B CB  1 
ATOM   4014  N N   . THR B 1 42  ? 125.595 153.966 155.423 1.00 36.06  ? 42  THR B N   1 
ATOM   4015  C CA  . THR B 1 42  ? 125.801 154.687 154.176 1.00 36.06  ? 42  THR B CA  1 
ATOM   4016  C C   . THR B 1 42  ? 125.463 153.787 152.995 1.00 36.06  ? 42  THR B C   1 
ATOM   4017  O O   . THR B 1 42  ? 125.642 152.568 153.050 1.00 36.06  ? 42  THR B O   1 
ATOM   4018  C CB  . THR B 1 42  ? 127.249 155.189 154.028 1.00 36.06  ? 42  THR B CB  1 
ATOM   4019  O OG1 . THR B 1 42  ? 128.133 154.072 153.873 1.00 36.06  ? 42  THR B OG1 1 
ATOM   4020  C CG2 . THR B 1 42  ? 127.669 155.999 155.242 1.00 36.06  ? 42  THR B CG2 1 
ATOM   4021  N N   . GLU B 1 43  ? 124.975 154.406 151.923 1.00 31.89  ? 43  GLU B N   1 
ATOM   4022  C CA  . GLU B 1 43  ? 124.661 153.698 150.691 1.00 31.89  ? 43  GLU B CA  1 
ATOM   4023  C C   . GLU B 1 43  ? 125.914 153.556 149.836 1.00 31.89  ? 43  GLU B C   1 
ATOM   4024  O O   . GLU B 1 43  ? 126.695 154.501 149.698 1.00 31.89  ? 43  GLU B O   1 
ATOM   4025  C CB  . GLU B 1 43  ? 123.569 154.435 149.912 1.00 31.89  ? 43  GLU B CB  1 
ATOM   4026  C CG  . GLU B 1 43  ? 123.212 153.796 148.584 1.00 31.89  ? 43  GLU B CG  1 
ATOM   4027  C CD  . GLU B 1 43  ? 122.587 152.426 148.747 1.00 31.89  ? 43  GLU B CD  1 
ATOM   4028  O OE1 . GLU B 1 43  ? 121.566 152.314 149.456 1.00 31.89  ? 43  GLU B OE1 1 
ATOM   4029  O OE2 . GLU B 1 43  ? 123.121 151.458 148.167 1.00 31.89  ? 43  GLU B OE2 1 
ATOM   4030  N N   . LEU B 1 44  ? 126.099 152.368 149.261 1.00 28.84  ? 44  LEU B N   1 
ATOM   4031  C CA  . LEU B 1 44  ? 127.309 152.041 148.520 1.00 28.84  ? 44  LEU B CA  1 
ATOM   4032  C C   . LEU B 1 44  ? 127.092 151.909 147.019 1.00 28.84  ? 44  LEU B C   1 
ATOM   4033  O O   . LEU B 1 44  ? 128.055 151.638 146.295 1.00 28.84  ? 44  LEU B O   1 
ATOM   4034  C CB  . LEU B 1 44  ? 127.918 150.741 149.057 1.00 28.84  ? 44  LEU B CB  1 
ATOM   4035  C CG  . LEU B 1 44  ? 128.506 150.770 150.467 1.00 28.84  ? 44  LEU B CG  1 
ATOM   4036  C CD1 . LEU B 1 44  ? 129.243 149.476 150.755 1.00 28.84  ? 44  LEU B CD1 1 
ATOM   4037  C CD2 . LEU B 1 44  ? 129.426 151.964 150.643 1.00 28.84  ? 44  LEU B CD2 1 
ATOM   4038  N N   . VAL B 1 45  ? 125.868 152.087 146.529 1.00 27.42  ? 45  VAL B N   1 
ATOM   4039  C CA  . VAL B 1 45  ? 125.551 151.924 145.115 1.00 27.42  ? 45  VAL B CA  1 
ATOM   4040  C C   . VAL B 1 45  ? 124.977 153.231 144.588 1.00 27.42  ? 45  VAL B C   1 
ATOM   4041  O O   . VAL B 1 45  ? 124.047 153.790 145.180 1.00 27.42  ? 45  VAL B O   1 
ATOM   4042  C CB  . VAL B 1 45  ? 124.565 150.763 144.883 1.00 27.42  ? 45  VAL B CB  1 
ATOM   4043  C CG1 . VAL B 1 45  ? 124.217 150.644 143.411 1.00 27.42  ? 45  VAL B CG1 1 
ATOM   4044  C CG2 . VAL B 1 45  ? 125.150 149.461 145.398 1.00 27.42  ? 45  VAL B CG2 1 
ATOM   4045  N N   . GLN B 1 46  ? 125.535 153.716 143.480 1.00 26.52  ? 46  GLN B N   1 
ATOM   4046  C CA  . GLN B 1 46  ? 125.027 154.898 142.792 1.00 26.52  ? 46  GLN B CA  1 
ATOM   4047  C C   . GLN B 1 46  ? 124.061 154.439 141.705 1.00 26.52  ? 46  GLN B C   1 
ATOM   4048  O O   . GLN B 1 46  ? 124.469 153.789 140.738 1.00 26.52  ? 46  GLN B O   1 
ATOM   4049  C CB  . GLN B 1 46  ? 126.177 155.710 142.204 1.00 26.52  ? 46  GLN B CB  1 
ATOM   4050  C CG  . GLN B 1 46  ? 125.744 156.861 141.316 1.00 26.52  ? 46  GLN B CG  1 
ATOM   4051  C CD  . GLN B 1 46  ? 125.390 158.100 142.106 1.00 26.52  ? 46  GLN B CD  1 
ATOM   4052  O OE1 . GLN B 1 46  ? 126.151 158.538 142.967 1.00 26.52  ? 46  GLN B OE1 1 
ATOM   4053  N NE2 . GLN B 1 46  ? 124.229 158.674 141.820 1.00 26.52  ? 46  GLN B NE2 1 
ATOM   4054  N N   . ASN B 1 47  ? 122.780 154.781 141.855 1.00 29.12  ? 47  ASN B N   1 
ATOM   4055  C CA  . ASN B 1 47  ? 121.737 154.264 140.976 1.00 29.12  ? 47  ASN B CA  1 
ATOM   4056  C C   . ASN B 1 47  ? 120.970 155.364 140.250 1.00 29.12  ? 47  ASN B C   1 
ATOM   4057  O O   . ASN B 1 47  ? 119.873 155.112 139.743 1.00 29.12  ? 47  ASN B O   1 
ATOM   4058  C CB  . ASN B 1 47  ? 120.768 153.382 141.768 1.00 29.12  ? 47  ASN B CB  1 
ATOM   4059  C CG  . ASN B 1 47  ? 119.959 154.166 142.781 1.00 29.12  ? 47  ASN B CG  1 
ATOM   4060  O OD1 . ASN B 1 47  ? 120.339 155.265 143.183 1.00 29.12  ? 47  ASN B OD1 1 
ATOM   4061  N ND2 . ASN B 1 47  ? 118.834 153.603 143.200 1.00 29.12  ? 47  ASN B ND2 1 
ATOM   4062  N N   . SER B 1 48  ? 121.517 156.575 140.176 1.00 29.95  ? 48  SER B N   1 
ATOM   4063  C CA  . SER B 1 48  ? 120.824 157.677 139.528 1.00 29.95  ? 48  SER B CA  1 
ATOM   4064  C C   . SER B 1 48  ? 121.811 158.505 138.720 1.00 29.95  ? 48  SER B C   1 
ATOM   4065  O O   . SER B 1 48  ? 123.022 158.474 138.952 1.00 29.95  ? 48  SER B O   1 
ATOM   4066  C CB  . SER B 1 48  ? 120.101 158.569 140.546 1.00 29.95  ? 48  SER B CB  1 
ATOM   4067  O OG  . SER B 1 48  ? 121.014 159.142 141.463 1.00 29.95  ? 48  SER B OG  1 
ATOM   4068  N N   . SER B 1 49  ? 121.270 159.250 137.758 1.00 32.25  ? 49  SER B N   1 
ATOM   4069  C CA  . SER B 1 49  ? 122.051 160.146 136.922 1.00 32.25  ? 49  SER B CA  1 
ATOM   4070  C C   . SER B 1 49  ? 121.238 161.404 136.650 1.00 32.25  ? 49  SER B C   1 
ATOM   4071  O O   . SER B 1 49  ? 120.015 161.421 136.801 1.00 32.25  ? 49  SER B O   1 
ATOM   4072  C CB  . SER B 1 49  ? 122.457 159.479 135.602 1.00 32.25  ? 49  SER B CB  1 
ATOM   4073  O OG  . SER B 1 49  ? 123.222 160.362 134.803 1.00 32.25  ? 49  SER B OG  1 
ATOM   4074  N N   . THR B 1 50  ? 121.936 162.467 136.250 1.00 35.77  ? 50  THR B N   1 
ATOM   4075  C CA  . THR B 1 50  ? 121.274 163.725 135.932 1.00 35.77  ? 50  THR B CA  1 
ATOM   4076  C C   . THR B 1 50  ? 120.784 163.795 134.492 1.00 35.77  ? 50  THR B C   1 
ATOM   4077  O O   . THR B 1 50  ? 119.991 164.687 134.169 1.00 35.77  ? 50  THR B O   1 
ATOM   4078  C CB  . THR B 1 50  ? 122.210 164.905 136.206 1.00 35.77  ? 50  THR B CB  1 
ATOM   4079  O OG1 . THR B 1 50  ? 123.355 164.822 135.347 1.00 35.77  ? 50  THR B OG1 1 
ATOM   4080  C CG2 . THR B 1 50  ? 122.667 164.896 137.655 1.00 35.77  ? 50  THR B CG2 1 
ATOM   4081  N N   . GLY B 1 51  ? 121.223 162.885 133.627 1.00 35.00  ? 51  GLY B N   1 
ATOM   4082  C CA  . GLY B 1 51  ? 120.803 162.892 132.242 1.00 35.00  ? 51  GLY B CA  1 
ATOM   4083  C C   . GLY B 1 51  ? 121.599 163.793 131.328 1.00 35.00  ? 51  GLY B C   1 
ATOM   4084  O O   . GLY B 1 51  ? 121.191 163.997 130.180 1.00 35.00  ? 51  GLY B O   1 
ATOM   4085  N N   . LYS B 1 52  ? 122.719 164.339 131.796 1.00 35.09  ? 52  LYS B N   1 
ATOM   4086  C CA  . LYS B 1 52  ? 123.554 165.226 131.002 1.00 35.09  ? 52  LYS B CA  1 
ATOM   4087  C C   . LYS B 1 52  ? 124.987 164.716 131.010 1.00 35.09  ? 52  LYS B C   1 
ATOM   4088  O O   . LYS B 1 52  ? 125.407 164.013 131.933 1.00 35.09  ? 52  LYS B O   1 
ATOM   4089  C CB  . LYS B 1 52  ? 123.520 166.664 131.533 1.00 35.09  ? 52  LYS B CB  1 
ATOM   4090  C CG  . LYS B 1 52  ? 122.141 167.156 131.936 1.00 35.09  ? 52  LYS B CG  1 
ATOM   4091  C CD  . LYS B 1 52  ? 121.262 167.393 130.725 1.00 35.09  ? 52  LYS B CD  1 
ATOM   4092  C CE  . LYS B 1 52  ? 119.885 167.880 131.133 1.00 35.09  ? 52  LYS B CE  1 
ATOM   4093  N NZ  . LYS B 1 52  ? 119.934 169.260 131.687 1.00 35.09  ? 52  LYS B NZ  1 
ATOM   4094  N N   . ILE B 1 53  ? 125.736 165.081 129.974 1.00 32.48  ? 53  ILE B N   1 
ATOM   4095  C CA  . ILE B 1 53  ? 127.137 164.704 129.830 1.00 32.48  ? 53  ILE B CA  1 
ATOM   4096  C C   . ILE B 1 53  ? 127.992 165.940 130.070 1.00 32.48  ? 53  ILE B C   1 
ATOM   4097  O O   . ILE B 1 53  ? 127.756 166.993 129.468 1.00 32.48  ? 53  ILE B O   1 
ATOM   4098  C CB  . ILE B 1 53  ? 127.421 164.098 128.445 1.00 32.48  ? 53  ILE B CB  1 
ATOM   4099  C CG1 . ILE B 1 53  ? 126.709 162.753 128.295 1.00 32.48  ? 53  ILE B CG1 1 
ATOM   4100  C CG2 . ILE B 1 53  ? 128.915 163.933 128.230 1.00 32.48  ? 53  ILE B CG2 1 
ATOM   4101  C CD1 . ILE B 1 53  ? 126.759 162.190 126.894 1.00 32.48  ? 53  ILE B CD1 1 
ATOM   4102  N N   . CYS B 1 54  ? 128.977 165.812 130.954 1.00 36.54  ? 54  CYS B N   1 
ATOM   4103  C CA  . CYS B 1 54  ? 129.885 166.910 131.248 1.00 36.54  ? 54  CYS B CA  1 
ATOM   4104  C C   . CYS B 1 54  ? 131.016 166.949 130.230 1.00 36.54  ? 54  CYS B C   1 
ATOM   4105  O O   . CYS B 1 54  ? 131.574 165.913 129.860 1.00 36.54  ? 54  CYS B O   1 
ATOM   4106  C CB  . CYS B 1 54  ? 130.455 166.765 132.659 1.00 36.54  ? 54  CYS B CB  1 
ATOM   4107  S SG  . CYS B 1 54  ? 129.255 167.034 133.984 1.00 36.54  ? 54  CYS B SG  1 
ATOM   4108  N N   . ASN B 1 55  ? 131.359 168.154 129.782 1.00 36.54  ? 55  ASN B N   1 
ATOM   4109  C CA  . ASN B 1 55  ? 132.407 168.343 128.789 1.00 36.54  ? 55  ASN B CA  1 
ATOM   4110  C C   . ASN B 1 55  ? 133.782 168.549 129.413 1.00 36.54  ? 55  ASN B C   1 
ATOM   4111  O O   . ASN B 1 55  ? 134.738 168.848 128.691 1.00 36.54  ? 55  ASN B O   1 
ATOM   4112  C CB  . ASN B 1 55  ? 132.065 169.523 127.876 1.00 36.54  ? 55  ASN B CB  1 
ATOM   4113  C CG  . ASN B 1 55  ? 132.049 170.843 128.612 1.00 36.54  ? 55  ASN B CG  1 
ATOM   4114  O OD1 . ASN B 1 55  ? 131.327 171.008 129.591 1.00 36.54  ? 55  ASN B OD1 1 
ATOM   4115  N ND2 . ASN B 1 55  ? 132.845 171.794 128.142 1.00 36.54  ? 55  ASN B ND2 1 
ATOM   4116  N N   . ASN B 1 56  ? 133.900 168.409 130.729 1.00 35.24  ? 56  ASN B N   1 
ATOM   4117  C CA  . ASN B 1 56  ? 135.168 168.490 131.433 1.00 35.24  ? 56  ASN B CA  1 
ATOM   4118  C C   . ASN B 1 56  ? 135.299 167.311 132.384 1.00 35.24  ? 56  ASN B C   1 
ATOM   4119  O O   . ASN B 1 56  ? 134.298 166.842 132.934 1.00 35.24  ? 56  ASN B O   1 
ATOM   4120  C CB  . ASN B 1 56  ? 135.281 169.803 132.222 1.00 35.24  ? 56  ASN B CB  1 
ATOM   4121  C CG  . ASN B 1 56  ? 135.877 170.927 131.401 1.00 35.24  ? 56  ASN B CG  1 
ATOM   4122  O OD1 . ASN B 1 56  ? 136.999 170.823 130.906 1.00 35.24  ? 56  ASN B OD1 1 
ATOM   4123  N ND2 . ASN B 1 56  ? 135.128 172.013 131.254 1.00 35.24  ? 56  ASN B ND2 1 
ATOM   4124  N N   . PRO B 1 57  ? 136.525 166.807 132.603 1.00 32.23  ? 57  PRO B N   1 
ATOM   4125  C CA  . PRO B 1 57  ? 137.778 167.261 131.992 1.00 32.23  ? 57  PRO B CA  1 
ATOM   4126  C C   . PRO B 1 57  ? 138.076 166.607 130.644 1.00 32.23  ? 57  PRO B C   1 
ATOM   4127  O O   . PRO B 1 57  ? 138.990 167.043 129.946 1.00 32.23  ? 57  PRO B O   1 
ATOM   4128  C CB  . PRO B 1 57  ? 138.822 166.852 133.025 1.00 32.23  ? 57  PRO B CB  1 
ATOM   4129  C CG  . PRO B 1 57  ? 138.265 165.607 133.614 1.00 32.23  ? 57  PRO B CG  1 
ATOM   4130  C CD  . PRO B 1 57  ? 136.763 165.755 133.606 1.00 32.23  ? 57  PRO B CD  1 
ATOM   4131  N N   . HIS B 1 58  ? 137.318 165.574 130.290 1.00 31.18  ? 58  HIS B N   1 
ATOM   4132  C CA  . HIS B 1 58  ? 137.515 164.892 129.021 1.00 31.18  ? 58  HIS B CA  1 
ATOM   4133  C C   . HIS B 1 58  ? 137.001 165.744 127.868 1.00 31.18  ? 58  HIS B C   1 
ATOM   4134  O O   . HIS B 1 58  ? 136.009 166.466 127.994 1.00 31.18  ? 58  HIS B O   1 
ATOM   4135  C CB  . HIS B 1 58  ? 136.803 163.540 129.016 1.00 31.18  ? 58  HIS B CB  1 
ATOM   4136  C CG  . HIS B 1 58  ? 137.064 162.709 130.233 1.00 31.18  ? 58  HIS B CG  1 
ATOM   4137  N ND1 . HIS B 1 58  ? 138.308 162.197 130.532 1.00 31.18  ? 58  HIS B ND1 1 
ATOM   4138  C CD2 . HIS B 1 58  ? 136.239 162.295 131.223 1.00 31.18  ? 58  HIS B CD2 1 
ATOM   4139  C CE1 . HIS B 1 58  ? 138.238 161.505 131.655 1.00 31.18  ? 58  HIS B CE1 1 
ATOM   4140  N NE2 . HIS B 1 58  ? 136.994 161.549 132.095 1.00 31.18  ? 58  HIS B NE2 1 
ATOM   4141  N N   . LYS B 1 59  ? 137.686 165.649 126.731 1.00 28.23  ? 59  LYS B N   1 
ATOM   4142  C CA  . LYS B 1 59  ? 137.268 166.357 125.526 1.00 28.23  ? 59  LYS B CA  1 
ATOM   4143  C C   . LYS B 1 59  ? 136.224 165.517 124.801 1.00 28.23  ? 59  LYS B C   1 
ATOM   4144  O O   . LYS B 1 59  ? 136.554 164.503 124.178 1.00 28.23  ? 59  LYS B O   1 
ATOM   4145  C CB  . LYS B 1 59  ? 138.463 166.642 124.622 1.00 28.23  ? 59  LYS B CB  1 
ATOM   4146  C CG  . LYS B 1 59  ? 138.103 167.455 123.394 1.00 28.23  ? 59  LYS B CG  1 
ATOM   4147  C CD  . LYS B 1 59  ? 139.266 167.566 122.430 1.00 28.23  ? 59  LYS B CD  1 
ATOM   4148  C CE  . LYS B 1 59  ? 138.979 168.606 121.361 1.00 28.23  ? 59  LYS B CE  1 
ATOM   4149  N NZ  . LYS B 1 59  ? 137.708 168.314 120.641 1.00 28.23  ? 59  LYS B NZ  1 
ATOM   4150  N N   . VAL B 1 60  ? 134.967 165.940 124.876 1.00 29.42  ? 60  VAL B N   1 
ATOM   4151  C CA  . VAL B 1 60  ? 133.852 165.223 124.271 1.00 29.42  ? 60  VAL B CA  1 
ATOM   4152  C C   . VAL B 1 60  ? 133.505 165.895 122.952 1.00 29.42  ? 60  VAL B C   1 
ATOM   4153  O O   . VAL B 1 60  ? 133.333 167.119 122.895 1.00 29.42  ? 60  VAL B O   1 
ATOM   4154  C CB  . VAL B 1 60  ? 132.637 165.191 125.213 1.00 29.42  ? 60  VAL B CB  1 
ATOM   4155  C CG1 . VAL B 1 60  ? 131.475 164.477 124.554 1.00 29.42  ? 60  VAL B CG1 1 
ATOM   4156  C CG2 . VAL B 1 60  ? 133.003 164.519 126.524 1.00 29.42  ? 60  VAL B CG2 1 
ATOM   4157  N N   . LEU B 1 61  ? 133.408 165.100 121.890 1.00 26.82  ? 61  LEU B N   1 
ATOM   4158  C CA  . LEU B 1 61  ? 133.065 165.588 120.561 1.00 26.82  ? 61  LEU B CA  1 
ATOM   4159  C C   . LEU B 1 61  ? 131.694 165.047 120.180 1.00 26.82  ? 61  LEU B C   1 
ATOM   4160  O O   . LEU B 1 61  ? 131.482 163.830 120.177 1.00 26.82  ? 61  LEU B O   1 
ATOM   4161  C CB  . LEU B 1 61  ? 134.118 165.169 119.535 1.00 26.82  ? 61  LEU B CB  1 
ATOM   4162  C CG  . LEU B 1 61  ? 133.933 165.676 118.104 1.00 26.82  ? 61  LEU B CG  1 
ATOM   4163  C CD1 . LEU B 1 61  ? 133.853 167.191 118.075 1.00 26.82  ? 61  LEU B CD1 1 
ATOM   4164  C CD2 . LEU B 1 61  ? 135.058 165.182 117.214 1.00 26.82  ? 61  LEU B CD2 1 
ATOM   4165  N N   . ASP B 1 62  ? 130.773 165.949 119.858 1.00 28.92  ? 62  ASP B N   1 
ATOM   4166  C CA  . ASP B 1 62  ? 129.414 165.578 119.493 1.00 28.92  ? 62  ASP B CA  1 
ATOM   4167  C C   . ASP B 1 62  ? 129.347 165.267 118.003 1.00 28.92  ? 62  ASP B C   1 
ATOM   4168  O O   . ASP B 1 62  ? 129.744 166.090 117.173 1.00 28.92  ? 62  ASP B O   1 
ATOM   4169  C CB  . ASP B 1 62  ? 128.441 166.702 119.846 1.00 28.92  ? 62  ASP B CB  1 
ATOM   4170  C CG  . ASP B 1 62  ? 126.999 166.247 119.850 1.00 28.92  ? 62  ASP B CG  1 
ATOM   4171  O OD1 . ASP B 1 62  ? 126.748 165.053 119.592 1.00 28.92  ? 62  ASP B OD1 1 
ATOM   4172  O OD2 . ASP B 1 62  ? 126.113 167.087 120.110 1.00 28.92  ? 62  ASP B OD2 1 
ATOM   4173  N N   . GLY B 1 63  ? 128.843 164.076 117.670 1.00 28.58  ? 63  GLY B N   1 
ATOM   4174  C CA  . GLY B 1 63  ? 128.713 163.689 116.277 1.00 28.58  ? 63  GLY B CA  1 
ATOM   4175  C C   . GLY B 1 63  ? 127.493 164.246 115.580 1.00 28.58  ? 63  GLY B C   1 
ATOM   4176  O O   . GLY B 1 63  ? 127.499 164.360 114.351 1.00 28.58  ? 63  GLY B O   1 
ATOM   4177  N N   . ARG B 1 64  ? 126.452 164.593 116.338 1.00 30.04  ? 64  ARG B N   1 
ATOM   4178  C CA  . ARG B 1 64  ? 125.218 165.153 115.797 1.00 30.04  ? 64  ARG B CA  1 
ATOM   4179  C C   . ARG B 1 64  ? 124.576 164.221 114.776 1.00 30.04  ? 64  ARG B C   1 
ATOM   4180  O O   . ARG B 1 64  ? 124.112 163.133 115.131 1.00 30.04  ? 64  ARG B O   1 
ATOM   4181  C CB  . ARG B 1 64  ? 125.482 166.531 115.186 1.00 30.04  ? 64  ARG B CB  1 
ATOM   4182  C CG  . ARG B 1 64  ? 125.775 167.594 116.227 1.00 30.04  ? 64  ARG B CG  1 
ATOM   4183  C CD  . ARG B 1 64  ? 126.610 168.728 115.670 1.00 30.04  ? 64  ARG B CD  1 
ATOM   4184  N NE  . ARG B 1 64  ? 126.634 169.862 116.585 1.00 30.04  ? 64  ARG B NE  1 
ATOM   4185  C CZ  . ARG B 1 64  ? 127.640 170.146 117.401 1.00 30.04  ? 64  ARG B CZ  1 
ATOM   4186  N NH1 . ARG B 1 64  ? 128.733 169.402 117.435 1.00 30.04  ? 64  ARG B NH1 1 
ATOM   4187  N NH2 . ARG B 1 64  ? 127.545 171.202 118.204 1.00 30.04  ? 64  ARG B NH2 1 
ATOM   4188  N N   . ASP B 1 65  ? 124.540 164.635 113.510 1.00 30.08  ? 65  ASP B N   1 
ATOM   4189  C CA  . ASP B 1 65  ? 123.908 163.856 112.454 1.00 30.08  ? 65  ASP B CA  1 
ATOM   4190  C C   . ASP B 1 65  ? 124.921 163.125 111.581 1.00 30.08  ? 65  ASP B C   1 
ATOM   4191  O O   . ASP B 1 65  ? 124.618 162.804 110.428 1.00 30.08  ? 65  ASP B O   1 
ATOM   4192  C CB  . ASP B 1 65  ? 123.019 164.757 111.595 1.00 30.08  ? 65  ASP B CB  1 
ATOM   4193  C CG  . ASP B 1 65  ? 123.723 166.024 111.155 1.00 30.08  ? 65  ASP B CG  1 
ATOM   4194  O OD1 . ASP B 1 65  ? 124.684 166.441 111.835 1.00 30.08  ? 65  ASP B OD1 1 
ATOM   4195  O OD2 . ASP B 1 65  ? 123.314 166.606 110.130 1.00 30.08  ? 65  ASP B OD2 1 
ATOM   4196  N N   . CYS B 1 66  ? 126.111 162.850 112.110 1.00 28.80  ? 66  CYS B N   1 
ATOM   4197  C CA  . CYS B 1 66  ? 127.168 162.175 111.373 1.00 28.80  ? 66  CYS B CA  1 
ATOM   4198  C C   . CYS B 1 66  ? 127.736 161.041 112.212 1.00 28.80  ? 66  CYS B C   1 
ATOM   4199  O O   . CYS B 1 66  ? 127.793 161.136 113.441 1.00 28.80  ? 66  CYS B O   1 
ATOM   4200  C CB  . CYS B 1 66  ? 128.293 163.147 110.999 1.00 28.80  ? 66  CYS B CB  1 
ATOM   4201  S SG  . CYS B 1 66  ? 127.915 164.241 109.619 1.00 28.80  ? 66  CYS B SG  1 
ATOM   4202  N N   . THR B 1 67  ? 128.152 159.971 111.543 1.00 24.58  ? 67  THR B N   1 
ATOM   4203  C CA  . THR B 1 67  ? 128.868 158.890 112.200 1.00 24.58  ? 67  THR B CA  1 
ATOM   4204  C C   . THR B 1 67  ? 130.371 159.068 112.006 1.00 24.58  ? 67  THR B C   1 
ATOM   4205  O O   . THR B 1 67  ? 130.829 159.894 111.215 1.00 24.58  ? 67  THR B O   1 
ATOM   4206  C CB  . THR B 1 67  ? 128.414 157.530 111.666 1.00 24.58  ? 67  THR B CB  1 
ATOM   4207  O OG1 . THR B 1 67  ? 128.693 157.444 110.263 1.00 24.58  ? 67  THR B OG1 1 
ATOM   4208  C CG2 . THR B 1 67  ? 126.925 157.333 111.896 1.00 24.58  ? 67  THR B CG2 1 
ATOM   4209  N N   . LEU B 1 68  ? 131.147 158.280 112.752 1.00 21.91  ? 68  LEU B N   1 
ATOM   4210  C CA  . LEU B 1 68  ? 132.600 158.393 112.674 1.00 21.91  ? 68  LEU B CA  1 
ATOM   4211  C C   . LEU B 1 68  ? 133.119 157.971 111.304 1.00 21.91  ? 68  LEU B C   1 
ATOM   4212  O O   . LEU B 1 68  ? 134.030 158.604 110.760 1.00 21.91  ? 68  LEU B O   1 
ATOM   4213  C CB  . LEU B 1 68  ? 133.248 157.562 113.780 1.00 21.91  ? 68  LEU B CB  1 
ATOM   4214  C CG  . LEU B 1 68  ? 134.766 157.680 113.918 1.00 21.91  ? 68  LEU B CG  1 
ATOM   4215  C CD1 . LEU B 1 68  ? 135.178 159.132 114.066 1.00 21.91  ? 68  LEU B CD1 1 
ATOM   4216  C CD2 . LEU B 1 68  ? 135.248 156.866 115.100 1.00 21.91  ? 68  LEU B CD2 1 
ATOM   4217  N N   . ILE B 1 69  ? 132.551 156.909 110.730 1.00 21.58  ? 69  ILE B N   1 
ATOM   4218  C CA  . ILE B 1 69  ? 132.977 156.462 109.407 1.00 21.58  ? 69  ILE B CA  1 
ATOM   4219  C C   . ILE B 1 69  ? 132.585 157.483 108.345 1.00 21.58  ? 69  ILE B C   1 
ATOM   4220  O O   . ILE B 1 69  ? 133.350 157.755 107.412 1.00 21.58  ? 69  ILE B O   1 
ATOM   4221  C CB  . ILE B 1 69  ? 132.394 155.070 109.103 1.00 21.58  ? 69  ILE B CB  1 
ATOM   4222  C CG1 . ILE B 1 69  ? 132.918 154.043 110.109 1.00 21.58  ? 69  ILE B CG1 1 
ATOM   4223  C CG2 . ILE B 1 69  ? 132.727 154.642 107.683 1.00 21.58  ? 69  ILE B CG2 1 
ATOM   4224  C CD1 . ILE B 1 69  ? 134.379 153.703 109.934 1.00 21.58  ? 69  ILE B CD1 1 
ATOM   4225  N N   . ASP B 1 70  ? 131.389 158.065 108.468 1.00 24.71  ? 70  ASP B N   1 
ATOM   4226  C CA  . ASP B 1 70  ? 130.964 159.099 107.530 1.00 24.71  ? 70  ASP B CA  1 
ATOM   4227  C C   . ASP B 1 70  ? 131.849 160.333 107.631 1.00 24.71  ? 70  ASP B C   1 
ATOM   4228  O O   . ASP B 1 70  ? 132.174 160.959 106.616 1.00 24.71  ? 70  ASP B O   1 
ATOM   4229  C CB  . ASP B 1 70  ? 129.504 159.470 107.784 1.00 24.71  ? 70  ASP B CB  1 
ATOM   4230  C CG  . ASP B 1 70  ? 128.538 158.585 107.030 1.00 24.71  ? 70  ASP B CG  1 
ATOM   4231  O OD1 . ASP B 1 70  ? 128.916 158.063 105.961 1.00 24.71  ? 70  ASP B OD1 1 
ATOM   4232  O OD2 . ASP B 1 70  ? 127.399 158.411 107.508 1.00 24.71  ? 70  ASP B OD2 1 
ATOM   4233  N N   . ALA B 1 71  ? 132.237 160.707 108.852 1.00 23.38  ? 71  ALA B N   1 
ATOM   4234  C CA  . ALA B 1 71  ? 133.121 161.853 109.030 1.00 23.38  ? 71  ALA B CA  1 
ATOM   4235  C C   . ALA B 1 71  ? 134.514 161.566 108.486 1.00 23.38  ? 71  ALA B C   1 
ATOM   4236  O O   . ALA B 1 71  ? 135.177 162.464 107.955 1.00 23.38  ? 71  ALA B O   1 
ATOM   4237  C CB  . ALA B 1 71  ? 133.188 162.240 110.506 1.00 23.38  ? 71  ALA B CB  1 
ATOM   4238  N N   . MET B 1 72  ? 134.978 160.321 108.616 1.00 22.28  ? 72  MET B N   1 
ATOM   4239  C CA  . MET B 1 72  ? 136.291 159.963 108.092 1.00 22.28  ? 72  MET B CA  1 
ATOM   4240  C C   . MET B 1 72  ? 136.299 159.943 106.568 1.00 22.28  ? 72  MET B C   1 
ATOM   4241  O O   . MET B 1 72  ? 137.258 160.408 105.942 1.00 22.28  ? 72  MET B O   1 
ATOM   4242  C CB  . MET B 1 72  ? 136.723 158.606 108.649 1.00 22.28  ? 72  MET B CB  1 
ATOM   4243  C CG  . MET B 1 72  ? 137.956 158.021 107.980 1.00 22.28  ? 72  MET B CG  1 
ATOM   4244  S SD  . MET B 1 72  ? 138.105 156.241 108.206 1.00 22.28  ? 72  MET B SD  1 
ATOM   4245  C CE  . MET B 1 72  ? 136.849 155.643 107.081 1.00 22.28  ? 72  MET B CE  1 
ATOM   4246  N N   . LEU B 1 73  ? 135.239 159.412 105.951 1.00 21.57  ? 73  LEU B N   1 
ATOM   4247  C CA  . LEU B 1 73  ? 135.219 159.277 104.497 1.00 21.57  ? 73  LEU B CA  1 
ATOM   4248  C C   . LEU B 1 73  ? 135.148 160.632 103.804 1.00 21.57  ? 73  LEU B C   1 
ATOM   4249  O O   . LEU B 1 73  ? 135.764 160.827 102.751 1.00 21.57  ? 73  LEU B O   1 
ATOM   4250  C CB  . LEU B 1 73  ? 134.049 158.394 104.064 1.00 21.57  ? 73  LEU B CB  1 
ATOM   4251  C CG  . LEU B 1 73  ? 134.212 156.889 104.275 1.00 21.57  ? 73  LEU B CG  1 
ATOM   4252  C CD1 . LEU B 1 73  ? 133.025 156.139 103.699 1.00 21.57  ? 73  LEU B CD1 1 
ATOM   4253  C CD2 . LEU B 1 73  ? 135.510 156.399 103.660 1.00 21.57  ? 73  LEU B CD2 1 
ATOM   4254  N N   . GLY B 1 74  ? 134.406 161.579 104.373 1.00 23.00  ? 74  GLY B N   1 
ATOM   4255  C CA  . GLY B 1 74  ? 134.248 162.873 103.740 1.00 23.00  ? 74  GLY B CA  1 
ATOM   4256  C C   . GLY B 1 74  ? 132.857 163.140 103.202 1.00 23.00  ? 74  GLY B C   1 
ATOM   4257  O O   . GLY B 1 74  ? 132.704 163.721 102.124 1.00 23.00  ? 74  GLY B O   1 
ATOM   4258  N N   . ASP B 1 75  ? 131.838 162.706 103.937 1.00 26.72  ? 75  ASP B N   1 
ATOM   4259  C CA  . ASP B 1 75  ? 130.463 162.998 103.561 1.00 26.72  ? 75  ASP B CA  1 
ATOM   4260  C C   . ASP B 1 75  ? 130.251 164.511 103.511 1.00 26.72  ? 75  ASP B C   1 
ATOM   4261  O O   . ASP B 1 75  ? 130.707 165.230 104.408 1.00 26.72  ? 75  ASP B O   1 
ATOM   4262  C CB  . ASP B 1 75  ? 129.499 162.357 104.562 1.00 26.72  ? 75  ASP B CB  1 
ATOM   4263  C CG  . ASP B 1 75  ? 128.142 162.044 103.963 1.00 26.72  ? 75  ASP B CG  1 
ATOM   4264  O OD1 . ASP B 1 75  ? 127.444 162.981 103.529 1.00 26.72  ? 75  ASP B OD1 1 
ATOM   4265  O OD2 . ASP B 1 75  ? 127.768 160.854 103.933 1.00 26.72  ? 75  ASP B OD2 1 
ATOM   4266  N N   . PRO B 1 76  ? 129.581 165.028 102.476 1.00 27.93  ? 76  PRO B N   1 
ATOM   4267  C CA  . PRO B 1 76  ? 129.462 166.489 102.331 1.00 27.93  ? 76  PRO B CA  1 
ATOM   4268  C C   . PRO B 1 76  ? 128.811 167.187 103.511 1.00 27.93  ? 76  PRO B C   1 
ATOM   4269  O O   . PRO B 1 76  ? 129.176 168.330 103.812 1.00 27.93  ? 76  PRO B O   1 
ATOM   4270  C CB  . PRO B 1 76  ? 128.617 166.639 101.060 1.00 27.93  ? 76  PRO B CB  1 
ATOM   4271  C CG  . PRO B 1 76  ? 128.913 165.423 100.280 1.00 27.93  ? 76  PRO B CG  1 
ATOM   4272  C CD  . PRO B 1 76  ? 129.113 164.317 101.275 1.00 27.93  ? 76  PRO B CD  1 
ATOM   4273  N N   . HIS B 1 77  ? 127.858 166.552 104.186 1.00 28.16  ? 77  HIS B N   1 
ATOM   4274  C CA  . HIS B 1 77  ? 127.258 167.146 105.372 1.00 28.16  ? 77  HIS B CA  1 
ATOM   4275  C C   . HIS B 1 77  ? 128.056 166.854 106.635 1.00 28.16  ? 77  HIS B C   1 
ATOM   4276  O O   . HIS B 1 77  ? 127.685 167.330 107.712 1.00 28.16  ? 77  HIS B O   1 
ATOM   4277  C CB  . HIS B 1 77  ? 125.805 166.674 105.528 1.00 28.16  ? 77  HIS B CB  1 
ATOM   4278  C CG  . HIS B 1 77  ? 125.658 165.335 106.182 1.00 28.16  ? 77  HIS B CG  1 
ATOM   4279  N ND1 . HIS B 1 77  ? 125.872 164.150 105.512 1.00 28.16  ? 77  HIS B ND1 1 
ATOM   4280  C CD2 . HIS B 1 77  ? 125.289 164.994 107.439 1.00 28.16  ? 77  HIS B CD2 1 
ATOM   4281  C CE1 . HIS B 1 77  ? 125.658 163.137 106.332 1.00 28.16  ? 77  HIS B CE1 1 
ATOM   4282  N NE2 . HIS B 1 77  ? 125.302 163.622 107.508 1.00 28.16  ? 77  HIS B NE2 1 
ATOM   4283  N N   . CYS B 1 78  ? 129.146 166.094 106.521 1.00 29.46  ? 78  CYS B N   1 
ATOM   4284  C CA  . CYS B 1 78  ? 130.070 165.844 107.620 1.00 29.46  ? 78  CYS B CA  1 
ATOM   4285  C C   . CYS B 1 78  ? 131.394 166.576 107.427 1.00 29.46  ? 78  CYS B C   1 
ATOM   4286  O O   . CYS B 1 78  ? 132.403 166.194 108.026 1.00 29.46  ? 78  CYS B O   1 
ATOM   4287  C CB  . CYS B 1 78  ? 130.315 164.343 107.774 1.00 29.46  ? 78  CYS B CB  1 
ATOM   4288  S SG  . CYS B 1 78  ? 128.827 163.357 108.035 1.00 29.46  ? 78  CYS B SG  1 
ATOM   4289  N N   . ASP B 1 79  ? 131.410 167.620 106.595 1.00 30.68  ? 79  ASP B N   1 
ATOM   4290  C CA  . ASP B 1 79  ? 132.646 168.312 106.250 1.00 30.68  ? 79  ASP B CA  1 
ATOM   4291  C C   . ASP B 1 79  ? 133.197 169.158 107.389 1.00 30.68  ? 79  ASP B C   1 
ATOM   4292  O O   . ASP B 1 79  ? 134.339 169.619 107.294 1.00 30.68  ? 79  ASP B O   1 
ATOM   4293  C CB  . ASP B 1 79  ? 132.423 169.194 105.021 1.00 30.68  ? 79  ASP B CB  1 
ATOM   4294  C CG  . ASP B 1 79  ? 132.605 168.438 103.719 1.00 30.68  ? 79  ASP B CG  1 
ATOM   4295  O OD1 . ASP B 1 79  ? 133.253 167.370 103.732 1.00 30.68  ? 79  ASP B OD1 1 
ATOM   4296  O OD2 . ASP B 1 79  ? 132.098 168.912 102.682 1.00 30.68  ? 79  ASP B OD2 1 
ATOM   4297  N N   . VAL B 1 80  ? 132.422 169.377 108.454 1.00 29.52  ? 80  VAL B N   1 
ATOM   4298  C CA  . VAL B 1 80  ? 132.897 170.177 109.581 1.00 29.52  ? 80  VAL B CA  1 
ATOM   4299  C C   . VAL B 1 80  ? 133.803 169.385 110.509 1.00 29.52  ? 80  VAL B C   1 
ATOM   4300  O O   . VAL B 1 80  ? 134.505 169.980 111.336 1.00 29.52  ? 80  VAL B O   1 
ATOM   4301  C CB  . VAL B 1 80  ? 131.690 170.750 110.350 1.00 29.52  ? 80  VAL B CB  1 
ATOM   4302  C CG1 . VAL B 1 80  ? 130.960 169.648 111.104 1.00 29.52  ? 80  VAL B CG1 1 
ATOM   4303  C CG2 . VAL B 1 80  ? 132.110 171.884 111.279 1.00 29.52  ? 80  VAL B CG2 1 
ATOM   4304  N N   . PHE B 1 81  ? 133.832 168.061 110.379 1.00 27.66  ? 81  PHE B N   1 
ATOM   4305  C CA  . PHE B 1 81  ? 134.624 167.199 111.243 1.00 27.66  ? 81  PHE B CA  1 
ATOM   4306  C C   . PHE B 1 81  ? 136.023 166.936 110.699 1.00 27.66  ? 81  PHE B C   1 
ATOM   4307  O O   . PHE B 1 81  ? 136.682 165.997 111.155 1.00 27.66  ? 81  PHE B O   1 
ATOM   4308  C CB  . PHE B 1 81  ? 133.900 165.869 111.462 1.00 27.66  ? 81  PHE B CB  1 
ATOM   4309  C CG  . PHE B 1 81  ? 132.691 165.976 112.344 1.00 27.66  ? 81  PHE B CG  1 
ATOM   4310  C CD1 . PHE B 1 81  ? 132.818 165.943 113.721 1.00 27.66  ? 81  PHE B CD1 1 
ATOM   4311  C CD2 . PHE B 1 81  ? 131.429 166.113 111.796 1.00 27.66  ? 81  PHE B CD2 1 
ATOM   4312  C CE1 . PHE B 1 81  ? 131.708 166.043 114.534 1.00 27.66  ? 81  PHE B CE1 1 
ATOM   4313  C CE2 . PHE B 1 81  ? 130.316 166.214 112.603 1.00 27.66  ? 81  PHE B CE2 1 
ATOM   4314  C CZ  . PHE B 1 81  ? 130.455 166.179 113.973 1.00 27.66  ? 81  PHE B CZ  1 
ATOM   4315  N N   . GLN B 1 82  ? 136.487 167.732 109.741 1.00 28.48  ? 82  GLN B N   1 
ATOM   4316  C CA  . GLN B 1 82  ? 137.810 167.520 109.170 1.00 28.48  ? 82  GLN B CA  1 
ATOM   4317  C C   . GLN B 1 82  ? 138.890 167.943 110.157 1.00 28.48  ? 82  GLN B C   1 
ATOM   4318  O O   . GLN B 1 82  ? 138.840 169.045 110.713 1.00 28.48  ? 82  GLN B O   1 
ATOM   4319  C CB  . GLN B 1 82  ? 137.954 168.296 107.862 1.00 28.48  ? 82  GLN B CB  1 
ATOM   4320  C CG  . GLN B 1 82  ? 137.158 167.713 106.710 1.00 28.48  ? 82  GLN B CG  1 
ATOM   4321  C CD  . GLN B 1 82  ? 137.453 168.400 105.395 1.00 28.48  ? 82  GLN B CD  1 
ATOM   4322  O OE1 . GLN B 1 82  ? 138.151 169.412 105.353 1.00 28.48  ? 82  GLN B OE1 1 
ATOM   4323  N NE2 . GLN B 1 82  ? 136.919 167.854 104.310 1.00 28.48  ? 82  GLN B NE2 1 
ATOM   4324  N N   . ASP B 1 83  ? 139.869 167.060 110.369 1.00 29.81  ? 83  ASP B N   1 
ATOM   4325  C CA  . ASP B 1 83  ? 141.002 167.317 111.259 1.00 29.81  ? 83  ASP B CA  1 
ATOM   4326  C C   . ASP B 1 83  ? 140.532 167.631 112.680 1.00 29.81  ? 83  ASP B C   1 
ATOM   4327  O O   . ASP B 1 83  ? 140.831 168.686 113.241 1.00 29.81  ? 83  ASP B O   1 
ATOM   4328  C CB  . ASP B 1 83  ? 141.888 168.438 110.712 1.00 29.81  ? 83  ASP B CB  1 
ATOM   4329  C CG  . ASP B 1 83  ? 142.665 168.019 109.479 1.00 29.81  ? 83  ASP B CG  1 
ATOM   4330  O OD1 . ASP B 1 83  ? 142.863 166.803 109.285 1.00 29.81  ? 83  ASP B OD1 1 
ATOM   4331  O OD2 . ASP B 1 83  ? 143.074 168.905 108.702 1.00 29.81  ? 83  ASP B OD2 1 
ATOM   4332  N N   . GLU B 1 84  ? 139.791 166.696 113.262 1.00 29.55  ? 84  GLU B N   1 
ATOM   4333  C CA  . GLU B 1 84  ? 139.251 166.845 114.604 1.00 29.55  ? 84  GLU B CA  1 
ATOM   4334  C C   . GLU B 1 84  ? 139.950 165.902 115.576 1.00 29.55  ? 84  GLU B C   1 
ATOM   4335  O O   . GLU B 1 84  ? 140.540 164.892 115.188 1.00 29.55  ? 84  GLU B O   1 
ATOM   4336  C CB  . GLU B 1 84  ? 137.744 166.580 114.616 1.00 29.55  ? 84  GLU B CB  1 
ATOM   4337  C CG  . GLU B 1 84  ? 136.902 167.730 114.096 1.00 29.55  ? 84  GLU B CG  1 
ATOM   4338  C CD  . GLU B 1 84  ? 136.526 168.721 115.179 1.00 29.55  ? 84  GLU B CD  1 
ATOM   4339  O OE1 . GLU B 1 84  ? 137.133 168.679 116.268 1.00 29.55  ? 84  GLU B OE1 1 
ATOM   4340  O OE2 . GLU B 1 84  ? 135.617 169.543 114.940 1.00 29.55  ? 84  GLU B OE2 1 
ATOM   4341  N N   . LYS B 1 85  ? 139.871 166.252 116.857 1.00 28.23  ? 85  LYS B N   1 
ATOM   4342  C CA  . LYS B 1 85  ? 140.428 165.452 117.936 1.00 28.23  ? 85  LYS B CA  1 
ATOM   4343  C C   . LYS B 1 85  ? 139.368 165.263 119.009 1.00 28.23  ? 85  LYS B C   1 
ATOM   4344  O O   . LYS B 1 85  ? 138.478 166.101 119.175 1.00 28.23  ? 85  LYS B O   1 
ATOM   4345  C CB  . LYS B 1 85  ? 141.676 166.108 118.544 1.00 28.23  ? 85  LYS B CB  1 
ATOM   4346  C CG  . LYS B 1 85  ? 142.859 166.207 117.597 1.00 28.23  ? 85  LYS B CG  1 
ATOM   4347  C CD  . LYS B 1 85  ? 142.905 167.560 116.906 1.00 28.23  ? 85  LYS B CD  1 
ATOM   4348  C CE  . LYS B 1 85  ? 143.762 167.512 115.651 1.00 28.23  ? 85  LYS B CE  1 
ATOM   4349  N NZ  . LYS B 1 85  ? 143.674 168.777 114.871 1.00 28.23  ? 85  LYS B NZ  1 
ATOM   4350  N N   . TRP B 1 86  ? 139.466 164.154 119.736 1.00 27.93  ? 86  TRP B N   1 
ATOM   4351  C CA  . TRP B 1 86  ? 138.474 163.852 120.758 1.00 27.93  ? 86  TRP B CA  1 
ATOM   4352  C C   . TRP B 1 86  ? 139.074 162.906 121.785 1.00 27.93  ? 86  TRP B C   1 
ATOM   4353  O O   . TRP B 1 86  ? 140.051 162.202 121.517 1.00 27.93  ? 86  TRP B O   1 
ATOM   4354  C CB  . TRP B 1 86  ? 137.211 163.235 120.145 1.00 27.93  ? 86  TRP B CB  1 
ATOM   4355  C CG  . TRP B 1 86  ? 137.452 161.924 119.448 1.00 27.93  ? 86  TRP B CG  1 
ATOM   4356  C CD1 . TRP B 1 86  ? 137.477 160.686 120.019 1.00 27.93  ? 86  TRP B CD1 1 
ATOM   4357  C CD2 . TRP B 1 86  ? 137.700 161.724 118.052 1.00 27.93  ? 86  TRP B CD2 1 
ATOM   4358  N NE1 . TRP B 1 86  ? 137.726 159.730 119.069 1.00 27.93  ? 86  TRP B NE1 1 
ATOM   4359  C CE2 . TRP B 1 86  ? 137.867 160.341 117.851 1.00 27.93  ? 86  TRP B CE2 1 
ATOM   4360  C CE3 . TRP B 1 86  ? 137.797 162.581 116.951 1.00 27.93  ? 86  TRP B CE3 1 
ATOM   4361  C CZ2 . TRP B 1 86  ? 138.127 159.796 116.598 1.00 27.93  ? 86  TRP B CZ2 1 
ATOM   4362  C CZ3 . TRP B 1 86  ? 138.054 162.037 115.710 1.00 27.93  ? 86  TRP B CZ3 1 
ATOM   4363  C CH2 . TRP B 1 86  ? 138.216 160.659 115.543 1.00 27.93  ? 86  TRP B CH2 1 
ATOM   4364  N N   . ASP B 1 87  ? 138.474 162.909 122.973 1.00 25.85  ? 87  ASP B N   1 
ATOM   4365  C CA  . ASP B 1 87  ? 138.677 161.860 123.964 1.00 25.85  ? 87  ASP B CA  1 
ATOM   4366  C C   . ASP B 1 87  ? 137.549 160.841 123.950 1.00 25.85  ? 87  ASP B C   1 
ATOM   4367  O O   . ASP B 1 87  ? 137.797 159.642 124.100 1.00 25.85  ? 87  ASP B O   1 
ATOM   4368  C CB  . ASP B 1 87  ? 138.804 162.460 125.368 1.00 25.85  ? 87  ASP B CB  1 
ATOM   4369  C CG  . ASP B 1 87  ? 140.224 162.864 125.704 1.00 25.85  ? 87  ASP B CG  1 
ATOM   4370  O OD1 . ASP B 1 87  ? 141.161 162.155 125.282 1.00 25.85  ? 87  ASP B OD1 1 
ATOM   4371  O OD2 . ASP B 1 87  ? 140.404 163.889 126.392 1.00 25.85  ? 87  ASP B OD2 1 
ATOM   4372  N N   . LEU B 1 88  ? 136.313 161.300 123.769 1.00 23.33  ? 88  LEU B N   1 
ATOM   4373  C CA  . LEU B 1 88  ? 135.164 160.428 123.581 1.00 23.33  ? 88  LEU B CA  1 
ATOM   4374  C C   . LEU B 1 88  ? 134.324 160.969 122.436 1.00 23.33  ? 88  LEU B C   1 
ATOM   4375  O O   . LEU B 1 88  ? 133.999 162.159 122.411 1.00 23.33  ? 88  LEU B O   1 
ATOM   4376  C CB  . LEU B 1 88  ? 134.323 160.325 124.858 1.00 23.33  ? 88  LEU B CB  1 
ATOM   4377  C CG  . LEU B 1 88  ? 133.210 159.277 124.844 1.00 23.33  ? 88  LEU B CG  1 
ATOM   4378  C CD1 . LEU B 1 88  ? 133.783 157.880 124.983 1.00 23.33  ? 88  LEU B CD1 1 
ATOM   4379  C CD2 . LEU B 1 88  ? 132.202 159.557 125.941 1.00 23.33  ? 88  LEU B CD2 1 
ATOM   4380  N N   . PHE B 1 89  ? 133.984 160.098 121.491 1.00 22.55  ? 89  PHE B N   1 
ATOM   4381  C CA  . PHE B 1 89  ? 133.119 160.443 120.371 1.00 22.55  ? 89  PHE B CA  1 
ATOM   4382  C C   . PHE B 1 89  ? 131.711 159.947 120.670 1.00 22.55  ? 89  PHE B C   1 
ATOM   4383  O O   . PHE B 1 89  ? 131.521 158.774 121.006 1.00 22.55  ? 89  PHE B O   1 
ATOM   4384  C CB  . PHE B 1 89  ? 133.642 159.829 119.071 1.00 22.55  ? 89  PHE B CB  1 
ATOM   4385  C CG  . PHE B 1 89  ? 133.033 160.417 117.828 1.00 22.55  ? 89  PHE B CG  1 
ATOM   4386  C CD1 . PHE B 1 89  ? 131.834 159.936 117.330 1.00 22.55  ? 89  PHE B CD1 1 
ATOM   4387  C CD2 . PHE B 1 89  ? 133.665 161.446 117.153 1.00 22.55  ? 89  PHE B CD2 1 
ATOM   4388  C CE1 . PHE B 1 89  ? 131.273 160.474 116.190 1.00 22.55  ? 89  PHE B CE1 1 
ATOM   4389  C CE2 . PHE B 1 89  ? 133.109 161.987 116.011 1.00 22.55  ? 89  PHE B CE2 1 
ATOM   4390  C CZ  . PHE B 1 89  ? 131.911 161.500 115.530 1.00 22.55  ? 89  PHE B CZ  1 
ATOM   4391  N N   . VAL B 1 90  ? 130.730 160.836 120.549 1.00 23.56  ? 90  VAL B N   1 
ATOM   4392  C CA  . VAL B 1 90  ? 129.341 160.526 120.866 1.00 23.56  ? 90  VAL B CA  1 
ATOM   4393  C C   . VAL B 1 90  ? 128.567 160.411 119.561 1.00 23.56  ? 90  VAL B C   1 
ATOM   4394  O O   . VAL B 1 90  ? 128.475 161.379 118.796 1.00 23.56  ? 90  VAL B O   1 
ATOM   4395  C CB  . VAL B 1 90  ? 128.716 161.586 121.785 1.00 23.56  ? 90  VAL B CB  1 
ATOM   4396  C CG1 . VAL B 1 90  ? 127.295 161.199 122.146 1.00 23.56  ? 90  VAL B CG1 1 
ATOM   4397  C CG2 . VAL B 1 90  ? 129.554 161.758 123.038 1.00 23.56  ? 90  VAL B CG2 1 
ATOM   4398  N N   . GLU B 1 91  ? 128.004 159.232 119.313 1.00 24.05  ? 91  GLU B N   1 
ATOM   4399  C CA  . GLU B 1 91  ? 127.201 158.974 118.126 1.00 24.05  ? 91  GLU B CA  1 
ATOM   4400  C C   . GLU B 1 91  ? 125.725 158.995 118.496 1.00 24.05  ? 91  GLU B C   1 
ATOM   4401  O O   . GLU B 1 91  ? 125.298 158.287 119.413 1.00 24.05  ? 91  GLU B O   1 
ATOM   4402  C CB  . GLU B 1 91  ? 127.569 157.628 117.501 1.00 24.05  ? 91  GLU B CB  1 
ATOM   4403  C CG  . GLU B 1 91  ? 128.616 157.721 116.407 1.00 24.05  ? 91  GLU B CG  1 
ATOM   4404  C CD  . GLU B 1 91  ? 128.904 156.383 115.762 1.00 24.05  ? 91  GLU B CD  1 
ATOM   4405  O OE1 . GLU B 1 91  ? 128.407 155.357 116.271 1.00 24.05  ? 91  GLU B OE1 1 
ATOM   4406  O OE2 . GLU B 1 91  ? 129.632 156.354 114.748 1.00 24.05  ? 91  GLU B OE2 1 
ATOM   4407  N N   . ARG B 1 92  ? 124.952 159.805 117.782 1.00 26.60  ? 92  ARG B N   1 
ATOM   4408  C CA  . ARG B 1 92  ? 123.524 159.926 118.024 1.00 26.60  ? 92  ARG B CA  1 
ATOM   4409  C C   . ARG B 1 92  ? 122.748 158.956 117.139 1.00 26.60  ? 92  ARG B C   1 
ATOM   4410  O O   . ARG B 1 92  ? 123.229 158.500 116.099 1.00 26.60  ? 92  ARG B O   1 
ATOM   4411  C CB  . ARG B 1 92  ? 123.055 161.359 117.772 1.00 26.60  ? 92  ARG B CB  1 
ATOM   4412  C CG  . ARG B 1 92  ? 123.956 162.424 118.375 1.00 26.60  ? 92  ARG B CG  1 
ATOM   4413  C CD  . ARG B 1 92  ? 124.088 162.252 119.876 1.00 26.60  ? 92  ARG B CD  1 
ATOM   4414  N NE  . ARG B 1 92  ? 124.455 163.495 120.542 1.00 26.60  ? 92  ARG B NE  1 
ATOM   4415  C CZ  . ARG B 1 92  ? 124.451 163.669 121.856 1.00 26.60  ? 92  ARG B CZ  1 
ATOM   4416  N NH1 . ARG B 1 92  ? 124.102 162.696 122.680 1.00 26.60  ? 92  ARG B NH1 1 
ATOM   4417  N NH2 . ARG B 1 92  ? 124.806 164.849 122.355 1.00 26.60  ? 92  ARG B NH2 1 
ATOM   4418  N N   . SER B 1 93  ? 121.528 158.640 117.571 1.00 27.52  ? 93  SER B N   1 
ATOM   4419  C CA  . SER B 1 93  ? 120.677 157.713 116.837 1.00 27.52  ? 93  SER B CA  1 
ATOM   4420  C C   . SER B 1 93  ? 120.004 158.351 115.629 1.00 27.52  ? 93  SER B C   1 
ATOM   4421  O O   . SER B 1 93  ? 119.365 157.637 114.850 1.00 27.52  ? 93  SER B O   1 
ATOM   4422  C CB  . SER B 1 93  ? 119.614 157.128 117.769 1.00 27.52  ? 93  SER B CB  1 
ATOM   4423  O OG  . SER B 1 93  ? 118.564 158.052 117.994 1.00 27.52  ? 93  SER B OG  1 
ATOM   4424  N N   . SER B 1 94  ? 120.132 159.664 115.453 1.00 27.50  ? 94  SER B N   1 
ATOM   4425  C CA  . SER B 1 94  ? 119.534 160.371 114.331 1.00 27.50  ? 94  SER B CA  1 
ATOM   4426  C C   . SER B 1 94  ? 120.514 160.591 113.185 1.00 27.50  ? 94  SER B C   1 
ATOM   4427  O O   . SER B 1 94  ? 120.204 161.338 112.253 1.00 27.50  ? 94  SER B O   1 
ATOM   4428  C CB  . SER B 1 94  ? 118.967 161.713 114.798 1.00 27.50  ? 94  SER B CB  1 
ATOM   4429  O OG  . SER B 1 94  ? 119.967 162.502 115.417 1.00 27.50  ? 94  SER B OG  1 
ATOM   4430  N N   . ALA B 1 95  ? 121.686 159.964 113.236 1.00 26.84  ? 95  ALA B N   1 
ATOM   4431  C CA  . ALA B 1 95  ? 122.669 160.114 112.175 1.00 26.84  ? 95  ALA B CA  1 
ATOM   4432  C C   . ALA B 1 95  ? 122.225 159.376 110.916 1.00 26.84  ? 95  ALA B C   1 
ATOM   4433  O O   . ALA B 1 95  ? 121.549 158.346 110.977 1.00 26.84  ? 95  ALA B O   1 
ATOM   4434  C CB  . ALA B 1 95  ? 124.030 159.598 112.635 1.00 26.84  ? 95  ALA B CB  1 
ATOM   4435  N N   . PHE B 1 96  ? 122.619 159.914 109.763 1.00 25.73  ? 96  PHE B N   1 
ATOM   4436  C CA  . PHE B 1 96  ? 122.242 159.342 108.479 1.00 25.73  ? 96  PHE B CA  1 
ATOM   4437  C C   . PHE B 1 96  ? 123.362 159.582 107.476 1.00 25.73  ? 96  PHE B C   1 
ATOM   4438  O O   . PHE B 1 96  ? 124.303 160.337 107.731 1.00 25.73  ? 96  PHE B O   1 
ATOM   4439  C CB  . PHE B 1 96  ? 120.917 159.929 107.973 1.00 25.73  ? 96  PHE B CB  1 
ATOM   4440  C CG  . PHE B 1 96  ? 120.954 161.415 107.752 1.00 25.73  ? 96  PHE B CG  1 
ATOM   4441  C CD1 . PHE B 1 96  ? 120.668 162.289 108.785 1.00 25.73  ? 96  PHE B CD1 1 
ATOM   4442  C CD2 . PHE B 1 96  ? 121.265 161.937 106.508 1.00 25.73  ? 96  PHE B CD2 1 
ATOM   4443  C CE1 . PHE B 1 96  ? 120.700 163.654 108.585 1.00 25.73  ? 96  PHE B CE1 1 
ATOM   4444  C CE2 . PHE B 1 96  ? 121.299 163.300 106.301 1.00 25.73  ? 96  PHE B CE2 1 
ATOM   4445  C CZ  . PHE B 1 96  ? 121.015 164.159 107.341 1.00 25.73  ? 96  PHE B CZ  1 
ATOM   4446  N N   . SER B 1 97  ? 123.249 158.924 106.325 1.00 24.45  ? 97  SER B N   1 
ATOM   4447  C CA  . SER B 1 97  ? 124.196 159.063 105.229 1.00 24.45  ? 97  SER B CA  1 
ATOM   4448  C C   . SER B 1 97  ? 123.521 159.751 104.050 1.00 24.45  ? 97  SER B C   1 
ATOM   4449  O O   . SER B 1 97  ? 122.345 159.506 103.768 1.00 24.45  ? 97  SER B O   1 
ATOM   4450  C CB  . SER B 1 97  ? 124.742 157.701 104.794 1.00 24.45  ? 97  SER B CB  1 
ATOM   4451  O OG  . SER B 1 97  ? 125.658 157.187 105.745 1.00 24.45  ? 97  SER B OG  1 
ATOM   4452  N N   . ASN B 1 98  ? 124.268 160.615 103.367 1.00 25.03  ? 98  ASN B N   1 
ATOM   4453  C CA  . ASN B 1 98  ? 123.734 161.393 102.254 1.00 25.03  ? 98  ASN B CA  1 
ATOM   4454  C C   . ASN B 1 98  ? 124.733 161.447 101.104 1.00 25.03  ? 98  ASN B C   1 
ATOM   4455  O O   . ASN B 1 98  ? 124.937 162.496 100.485 1.00 25.03  ? 98  ASN B O   1 
ATOM   4456  C CB  . ASN B 1 98  ? 123.352 162.801 102.707 1.00 25.03  ? 98  ASN B CB  1 
ATOM   4457  C CG  . ASN B 1 98  ? 122.125 163.329 101.996 1.00 25.03  ? 98  ASN B CG  1 
ATOM   4458  O OD1 . ASN B 1 98  ? 121.205 162.577 101.679 1.00 25.03  ? 98  ASN B OD1 1 
ATOM   4459  N ND2 . ASN B 1 98  ? 122.102 164.632 101.746 1.00 25.03  ? 98  ASN B ND2 1 
ATOM   4460  N N   . CYS B 1 99  ? 125.365 160.320 100.798 1.00 23.53  ? 99  CYS B N   1 
ATOM   4461  C CA  . CYS B 1 99  ? 126.347 160.250 99.720  1.00 23.53  ? 99  CYS B CA  1 
ATOM   4462  C C   . CYS B 1 99  ? 126.146 158.928 98.985  1.00 23.53  ? 99  CYS B C   1 
ATOM   4463  O O   . CYS B 1 99  ? 125.111 158.267 99.121  1.00 23.53  ? 99  CYS B O   1 
ATOM   4464  C CB  . CYS B 1 99  ? 127.772 160.427 100.267 1.00 23.53  ? 99  CYS B CB  1 
ATOM   4465  S SG  . CYS B 1 99  ? 129.027 160.763 99.002  1.00 23.53  ? 99  CYS B SG  1 
ATOM   4466  N N   . TYR B 1 100 ? 127.135 158.546 98.183  1.00 21.41  ? 100 TYR B N   1 
ATOM   4467  C CA  . TYR B 1 100 ? 127.049 157.323 97.397  1.00 21.41  ? 100 TYR B CA  1 
ATOM   4468  C C   . TYR B 1 100 ? 126.900 156.113 98.315  1.00 21.41  ? 100 TYR B C   1 
ATOM   4469  O O   . TYR B 1 100 ? 127.601 156.025 99.332  1.00 21.41  ? 100 TYR B O   1 
ATOM   4470  C CB  . TYR B 1 100 ? 128.297 157.173 96.526  1.00 21.41  ? 100 TYR B CB  1 
ATOM   4471  C CG  . TYR B 1 100 ? 128.082 156.394 95.249  1.00 21.41  ? 100 TYR B CG  1 
ATOM   4472  C CD1 . TYR B 1 100 ? 127.681 157.030 94.084  1.00 21.41  ? 100 TYR B CD1 1 
ATOM   4473  C CD2 . TYR B 1 100 ? 128.287 155.022 95.207  1.00 21.41  ? 100 TYR B CD2 1 
ATOM   4474  C CE1 . TYR B 1 100 ? 127.487 156.323 92.916  1.00 21.41  ? 100 TYR B CE1 1 
ATOM   4475  C CE2 . TYR B 1 100 ? 128.093 154.307 94.045  1.00 21.41  ? 100 TYR B CE2 1 
ATOM   4476  C CZ  . TYR B 1 100 ? 127.693 154.962 92.903  1.00 21.41  ? 100 TYR B CZ  1 
ATOM   4477  O OH  . TYR B 1 100 ? 127.500 154.253 91.742  1.00 21.41  ? 100 TYR B OH  1 
ATOM   4478  N N   . PRO B 1 101 ? 125.998 155.179 98.010  1.00 20.51  ? 101 PRO B N   1 
ATOM   4479  C CA  . PRO B 1 101 ? 125.845 153.994 98.865  1.00 20.51  ? 101 PRO B CA  1 
ATOM   4480  C C   . PRO B 1 101 ? 127.123 153.169 98.911  1.00 20.51  ? 101 PRO B C   1 
ATOM   4481  O O   . PRO B 1 101 ? 127.830 153.026 97.913  1.00 20.51  ? 101 PRO B O   1 
ATOM   4482  C CB  . PRO B 1 101 ? 124.697 153.221 98.203  1.00 20.51  ? 101 PRO B CB  1 
ATOM   4483  C CG  . PRO B 1 101 ? 124.574 153.790 96.828  1.00 20.51  ? 101 PRO B CG  1 
ATOM   4484  C CD  . PRO B 1 101 ? 125.005 155.211 96.925  1.00 20.51  ? 101 PRO B CD  1 
ATOM   4485  N N   . TYR B 1 102 ? 127.410 152.616 100.087 1.00 20.18  ? 102 TYR B N   1 
ATOM   4486  C CA  . TYR B 1 102 ? 128.656 151.898 100.301 1.00 20.18  ? 102 TYR B CA  1 
ATOM   4487  C C   . TYR B 1 102 ? 128.469 150.860 101.396 1.00 20.18  ? 102 TYR B C   1 
ATOM   4488  O O   . TYR B 1 102 ? 127.501 150.897 102.159 1.00 20.18  ? 102 TYR B O   1 
ATOM   4489  C CB  . TYR B 1 102 ? 129.801 152.857 100.663 1.00 20.18  ? 102 TYR B CB  1 
ATOM   4490  C CG  . TYR B 1 102 ? 129.671 153.504 102.026 1.00 20.18  ? 102 TYR B CG  1 
ATOM   4491  C CD1 . TYR B 1 102 ? 129.004 154.710 102.179 1.00 20.18  ? 102 TYR B CD1 1 
ATOM   4492  C CD2 . TYR B 1 102 ? 130.226 152.917 103.156 1.00 20.18  ? 102 TYR B CD2 1 
ATOM   4493  C CE1 . TYR B 1 102 ? 128.883 155.307 103.417 1.00 20.18  ? 102 TYR B CE1 1 
ATOM   4494  C CE2 . TYR B 1 102 ? 130.108 153.506 104.398 1.00 20.18  ? 102 TYR B CE2 1 
ATOM   4495  C CZ  . TYR B 1 102 ? 129.437 154.702 104.522 1.00 20.18  ? 102 TYR B CZ  1 
ATOM   4496  O OH  . TYR B 1 102 ? 129.319 155.296 105.757 1.00 20.18  ? 102 TYR B OH  1 
ATOM   4497  N N   . ASP B 1 103 ? 129.415 149.926 101.459 1.00 20.61  ? 103 ASP B N   1 
ATOM   4498  C CA  . ASP B 1 103 ? 129.482 148.950 102.536 1.00 20.61  ? 103 ASP B CA  1 
ATOM   4499  C C   . ASP B 1 103 ? 130.937 148.739 102.921 1.00 20.61  ? 103 ASP B C   1 
ATOM   4500  O O   . ASP B 1 103 ? 131.834 148.804 102.078 1.00 20.61  ? 103 ASP B O   1 
ATOM   4501  C CB  . ASP B 1 103 ? 128.839 147.613 102.141 1.00 20.61  ? 103 ASP B CB  1 
ATOM   4502  C CG  . ASP B 1 103 ? 129.604 146.895 101.049 1.00 20.61  ? 103 ASP B CG  1 
ATOM   4503  O OD1 . ASP B 1 103 ? 129.445 147.266 99.867  1.00 20.61  ? 103 ASP B OD1 1 
ATOM   4504  O OD2 . ASP B 1 103 ? 130.360 145.955 101.371 1.00 20.61  ? 103 ASP B OD2 1 
ATOM   4505  N N   . VAL B 1 104 ? 131.163 148.495 104.207 1.00 18.88  ? 104 VAL B N   1 
ATOM   4506  C CA  . VAL B 1 104 ? 132.508 148.262 104.728 1.00 18.88  ? 104 VAL B CA  1 
ATOM   4507  C C   . VAL B 1 104 ? 132.600 146.829 105.238 1.00 18.88  ? 104 VAL B C   1 
ATOM   4508  O O   . VAL B 1 104 ? 131.994 146.503 106.268 1.00 18.88  ? 104 VAL B O   1 
ATOM   4509  C CB  . VAL B 1 104 ? 132.859 149.264 105.841 1.00 18.88  ? 104 VAL B CB  1 
ATOM   4510  C CG1 . VAL B 1 104 ? 134.321 149.134 106.227 1.00 18.88  ? 104 VAL B CG1 1 
ATOM   4511  C CG2 . VAL B 1 104 ? 132.546 150.681 105.400 1.00 18.88  ? 104 VAL B CG2 1 
ATOM   4512  N N   . PRO B 1 105 ? 133.317 145.941 104.552 1.00 19.95  ? 105 PRO B N   1 
ATOM   4513  C CA  . PRO B 1 105 ? 133.542 144.601 105.106 1.00 19.95  ? 105 PRO B CA  1 
ATOM   4514  C C   . PRO B 1 105 ? 134.336 144.686 106.402 1.00 19.95  ? 105 PRO B C   1 
ATOM   4515  O O   . PRO B 1 105 ? 135.381 145.338 106.468 1.00 19.95  ? 105 PRO B O   1 
ATOM   4516  C CB  . PRO B 1 105 ? 134.326 143.883 104.001 1.00 19.95  ? 105 PRO B CB  1 
ATOM   4517  C CG  . PRO B 1 105 ? 134.078 144.680 102.763 1.00 19.95  ? 105 PRO B CG  1 
ATOM   4518  C CD  . PRO B 1 105 ? 133.893 146.093 103.206 1.00 19.95  ? 105 PRO B CD  1 
ATOM   4519  N N   . ASP B 1 106 ? 133.823 144.020 107.437 1.00 22.68  ? 106 ASP B N   1 
ATOM   4520  C CA  . ASP B 1 106 ? 134.365 144.099 108.794 1.00 22.68  ? 106 ASP B CA  1 
ATOM   4521  C C   . ASP B 1 106 ? 134.328 145.549 109.290 1.00 22.68  ? 106 ASP B C   1 
ATOM   4522  O O   . ASP B 1 106 ? 135.349 146.168 109.593 1.00 22.68  ? 106 ASP B O   1 
ATOM   4523  C CB  . ASP B 1 106 ? 135.779 143.507 108.857 1.00 22.68  ? 106 ASP B CB  1 
ATOM   4524  C CG  . ASP B 1 106 ? 136.297 143.365 110.275 1.00 22.68  ? 106 ASP B CG  1 
ATOM   4525  O OD1 . ASP B 1 106 ? 135.579 143.750 111.222 1.00 22.68  ? 106 ASP B OD1 1 
ATOM   4526  O OD2 . ASP B 1 106 ? 137.429 142.863 110.443 1.00 22.68  ? 106 ASP B OD2 1 
ATOM   4527  N N   . TYR B 1 107 ? 133.104 146.079 109.353 1.00 19.98  ? 107 TYR B N   1 
ATOM   4528  C CA  . TYR B 1 107 ? 132.885 147.482 109.697 1.00 19.98  ? 107 TYR B CA  1 
ATOM   4529  C C   . TYR B 1 107 ? 133.317 147.785 111.128 1.00 19.98  ? 107 TYR B C   1 
ATOM   4530  O O   . TYR B 1 107 ? 133.885 148.851 111.405 1.00 19.98  ? 107 TYR B O   1 
ATOM   4531  C CB  . TYR B 1 107 ? 131.405 147.814 109.482 1.00 19.98  ? 107 TYR B CB  1 
ATOM   4532  C CG  . TYR B 1 107 ? 130.941 149.183 109.931 1.00 19.98  ? 107 TYR B CG  1 
ATOM   4533  C CD1 . TYR B 1 107 ? 130.507 149.400 111.232 1.00 19.98  ? 107 TYR B CD1 1 
ATOM   4534  C CD2 . TYR B 1 107 ? 130.899 150.247 109.043 1.00 19.98  ? 107 TYR B CD2 1 
ATOM   4535  C CE1 . TYR B 1 107 ? 130.070 150.643 111.641 1.00 19.98  ? 107 TYR B CE1 1 
ATOM   4536  C CE2 . TYR B 1 107 ? 130.460 151.494 109.443 1.00 19.98  ? 107 TYR B CE2 1 
ATOM   4537  C CZ  . TYR B 1 107 ? 130.048 151.686 110.742 1.00 19.98  ? 107 TYR B CZ  1 
ATOM   4538  O OH  . TYR B 1 107 ? 129.611 152.926 111.147 1.00 19.98  ? 107 TYR B OH  1 
ATOM   4539  N N   . ALA B 1 108 ? 133.055 146.856 112.050 1.00 20.13  ? 108 ALA B N   1 
ATOM   4540  C CA  . ALA B 1 108 ? 133.316 147.102 113.464 1.00 20.13  ? 108 ALA B CA  1 
ATOM   4541  C C   . ALA B 1 108 ? 134.803 147.280 113.743 1.00 20.13  ? 108 ALA B C   1 
ATOM   4542  O O   . ALA B 1 108 ? 135.185 148.101 114.584 1.00 20.13  ? 108 ALA B O   1 
ATOM   4543  C CB  . ALA B 1 108 ? 132.744 145.963 114.305 1.00 20.13  ? 108 ALA B CB  1 
ATOM   4544  N N   . SER B 1 109 ? 135.659 146.517 113.058 1.00 20.70  ? 109 SER B N   1 
ATOM   4545  C CA  . SER B 1 109 ? 137.097 146.636 113.281 1.00 20.70  ? 109 SER B CA  1 
ATOM   4546  C C   . SER B 1 109 ? 137.604 148.018 112.886 1.00 20.70  ? 109 SER B C   1 
ATOM   4547  O O   . SER B 1 109 ? 138.376 148.642 113.622 1.00 20.70  ? 109 SER B O   1 
ATOM   4548  C CB  . SER B 1 109 ? 137.840 145.549 112.507 1.00 20.70  ? 109 SER B CB  1 
ATOM   4549  O OG  . SER B 1 109 ? 137.692 144.288 113.132 1.00 20.70  ? 109 SER B OG  1 
ATOM   4550  N N   . LEU B 1 110 ? 137.175 148.514 111.723 1.00 18.98  ? 110 LEU B N   1 
ATOM   4551  C CA  . LEU B 1 110 ? 137.592 149.844 111.291 1.00 18.98  ? 110 LEU B CA  1 
ATOM   4552  C C   . LEU B 1 110 ? 137.030 150.923 112.206 1.00 18.98  ? 110 LEU B C   1 
ATOM   4553  O O   . LEU B 1 110 ? 137.724 151.897 112.527 1.00 18.98  ? 110 LEU B O   1 
ATOM   4554  C CB  . LEU B 1 110 ? 137.161 150.087 109.845 1.00 18.98  ? 110 LEU B CB  1 
ATOM   4555  C CG  . LEU B 1 110 ? 137.644 151.391 109.206 1.00 18.98  ? 110 LEU B CG  1 
ATOM   4556  C CD1 . LEU B 1 110 ? 139.161 151.449 109.181 1.00 18.98  ? 110 LEU B CD1 1 
ATOM   4557  C CD2 . LEU B 1 110 ? 137.078 151.544 107.806 1.00 18.98  ? 110 LEU B CD2 1 
ATOM   4558  N N   . ARG B 1 111 ? 135.774 150.771 112.636 1.00 19.69  ? 111 ARG B N   1 
ATOM   4559  C CA  . ARG B 1 111 ? 135.196 151.746 113.555 1.00 19.69  ? 111 ARG B CA  1 
ATOM   4560  C C   . ARG B 1 111 ? 135.977 151.796 114.863 1.00 19.69  ? 111 ARG B C   1 
ATOM   4561  O O   . ARG B 1 111 ? 136.288 152.881 115.368 1.00 19.69  ? 111 ARG B O   1 
ATOM   4562  C CB  . ARG B 1 111 ? 133.726 151.413 113.811 1.00 19.69  ? 111 ARG B CB  1 
ATOM   4563  C CG  . ARG B 1 111 ? 133.019 152.368 114.757 1.00 19.69  ? 111 ARG B CG  1 
ATOM   4564  C CD  . ARG B 1 111 ? 131.563 151.973 114.932 1.00 19.69  ? 111 ARG B CD  1 
ATOM   4565  N NE  . ARG B 1 111 ? 130.906 152.724 115.995 1.00 19.69  ? 111 ARG B NE  1 
ATOM   4566  C CZ  . ARG B 1 111 ? 130.883 152.355 117.268 1.00 19.69  ? 111 ARG B CZ  1 
ATOM   4567  N NH1 . ARG B 1 111 ? 131.494 151.258 117.680 1.00 19.69  ? 111 ARG B NH1 1 
ATOM   4568  N NH2 . ARG B 1 111 ? 130.230 153.106 118.150 1.00 19.69  ? 111 ARG B NH2 1 
ATOM   4569  N N   . SER B 1 112 ? 136.320 150.629 115.414 1.00 20.70  ? 112 SER B N   1 
ATOM   4570  C CA  . SER B 1 112 ? 137.101 150.579 116.647 1.00 20.70  ? 112 SER B CA  1 
ATOM   4571  C C   . SER B 1 112 ? 138.489 151.175 116.451 1.00 20.70  ? 112 SER B C   1 
ATOM   4572  O O   . SER B 1 112 ? 138.991 151.894 117.322 1.00 20.70  ? 112 SER B O   1 
ATOM   4573  C CB  . SER B 1 112 ? 137.201 149.136 117.139 1.00 20.70  ? 112 SER B CB  1 
ATOM   4574  O OG  . SER B 1 112 ? 138.001 149.046 118.303 1.00 20.70  ? 112 SER B OG  1 
ATOM   4575  N N   . LEU B 1 113 ? 139.127 150.879 115.317 1.00 21.55  ? 113 LEU B N   1 
ATOM   4576  C CA  . LEU B 1 113 ? 140.454 151.417 115.037 1.00 21.55  ? 113 LEU B CA  1 
ATOM   4577  C C   . LEU B 1 113 ? 140.433 152.940 114.995 1.00 21.55  ? 113 LEU B C   1 
ATOM   4578  O O   . LEU B 1 113 ? 141.266 153.605 115.624 1.00 21.55  ? 113 LEU B O   1 
ATOM   4579  C CB  . LEU B 1 113 ? 140.967 150.834 113.717 1.00 21.55  ? 113 LEU B CB  1 
ATOM   4580  C CG  . LEU B 1 113 ? 142.397 151.069 113.227 1.00 21.55  ? 113 LEU B CG  1 
ATOM   4581  C CD1 . LEU B 1 113 ? 142.812 149.918 112.335 1.00 21.55  ? 113 LEU B CD1 1 
ATOM   4582  C CD2 . LEU B 1 113 ? 142.521 152.376 112.464 1.00 21.55  ? 113 LEU B CD2 1 
ATOM   4583  N N   . ILE B 1 114 ? 139.475 153.513 114.263 1.00 21.60  ? 114 ILE B N   1 
ATOM   4584  C CA  . ILE B 1 114 ? 139.412 154.967 114.145 1.00 21.60  ? 114 ILE B CA  1 
ATOM   4585  C C   . ILE B 1 114 ? 139.032 155.602 115.478 1.00 21.60  ? 114 ILE B C   1 
ATOM   4586  O O   . ILE B 1 114 ? 139.538 156.673 115.833 1.00 21.60  ? 114 ILE B O   1 
ATOM   4587  C CB  . ILE B 1 114 ? 138.446 155.377 113.019 1.00 21.60  ? 114 ILE B CB  1 
ATOM   4588  C CG1 . ILE B 1 114 ? 138.848 154.698 111.711 1.00 21.60  ? 114 ILE B CG1 1 
ATOM   4589  C CG2 . ILE B 1 114 ? 138.429 156.887 112.849 1.00 21.60  ? 114 ILE B CG2 1 
ATOM   4590  C CD1 . ILE B 1 114 ? 140.060 155.315 111.054 1.00 21.60  ? 114 ILE B CD1 1 
ATOM   4591  N N   . ALA B 1 115 ? 138.136 154.963 116.237 1.00 21.82  ? 115 ALA B N   1 
ATOM   4592  C CA  . ALA B 1 115 ? 137.768 155.500 117.543 1.00 21.82  ? 115 ALA B CA  1 
ATOM   4593  C C   . ALA B 1 115 ? 138.958 155.514 118.492 1.00 21.82  ? 115 ALA B C   1 
ATOM   4594  O O   . ALA B 1 115 ? 139.185 156.501 119.200 1.00 21.82  ? 115 ALA B O   1 
ATOM   4595  C CB  . ALA B 1 115 ? 136.620 154.689 118.137 1.00 21.82  ? 115 ALA B CB  1 
ATOM   4596  N N   . SER B 1 116 ? 139.733 154.428 118.518 1.00 23.34  ? 116 SER B N   1 
ATOM   4597  C CA  . SER B 1 116 ? 140.878 154.344 119.415 1.00 23.34  ? 116 SER B CA  1 
ATOM   4598  C C   . SER B 1 116 ? 142.040 155.216 118.960 1.00 23.34  ? 116 SER B C   1 
ATOM   4599  O O   . SER B 1 116 ? 142.882 155.579 119.788 1.00 23.34  ? 116 SER B O   1 
ATOM   4600  C CB  . SER B 1 116 ? 141.332 152.891 119.543 1.00 23.34  ? 116 SER B CB  1 
ATOM   4601  O OG  . SER B 1 116 ? 142.453 152.779 120.399 1.00 23.34  ? 116 SER B OG  1 
ATOM   4602  N N   . SER B 1 117 ? 142.115 155.551 117.669 1.00 25.23  ? 117 SER B N   1 
ATOM   4603  C CA  . SER B 1 117 ? 143.175 156.444 117.206 1.00 25.23  ? 117 SER B CA  1 
ATOM   4604  C C   . SER B 1 117 ? 143.047 157.828 117.834 1.00 25.23  ? 117 SER B C   1 
ATOM   4605  O O   . SER B 1 117 ? 144.044 158.415 118.268 1.00 25.23  ? 117 SER B O   1 
ATOM   4606  C CB  . SER B 1 117 ? 143.154 156.540 115.682 1.00 25.23  ? 117 SER B CB  1 
ATOM   4607  O OG  . SER B 1 117 ? 144.150 157.433 115.217 1.00 25.23  ? 117 SER B OG  1 
ATOM   4608  N N   . GLY B 1 118 ? 141.831 158.365 117.889 1.00 24.10  ? 118 GLY B N   1 
ATOM   4609  C CA  . GLY B 1 118 ? 141.573 159.610 118.582 1.00 24.10  ? 118 GLY B CA  1 
ATOM   4610  C C   . GLY B 1 118 ? 141.736 160.875 117.771 1.00 24.10  ? 118 GLY B C   1 
ATOM   4611  O O   . GLY B 1 118 ? 141.637 161.967 118.342 1.00 24.10  ? 118 GLY B O   1 
ATOM   4612  N N   . THR B 1 119 ? 141.976 160.774 116.467 1.00 25.46  ? 119 THR B N   1 
ATOM   4613  C CA  . THR B 1 119 ? 142.165 161.963 115.648 1.00 25.46  ? 119 THR B CA  1 
ATOM   4614  C C   . THR B 1 119 ? 141.782 161.646 114.210 1.00 25.46  ? 119 THR B C   1 
ATOM   4615  O O   . THR B 1 119 ? 141.753 160.485 113.797 1.00 25.46  ? 119 THR B O   1 
ATOM   4616  C CB  . THR B 1 119 ? 143.609 162.473 115.723 1.00 25.46  ? 119 THR B CB  1 
ATOM   4617  O OG1 . THR B 1 119 ? 143.737 163.674 114.953 1.00 25.46  ? 119 THR B OG1 1 
ATOM   4618  C CG2 . THR B 1 119 ? 144.575 161.428 115.191 1.00 25.46  ? 119 THR B CG2 1 
ATOM   4619  N N   . LEU B 1 120 ? 141.484 162.702 113.456 1.00 24.46  ? 120 LEU B N   1 
ATOM   4620  C CA  . LEU B 1 120 ? 141.130 162.610 112.045 1.00 24.46  ? 120 LEU B CA  1 
ATOM   4621  C C   . LEU B 1 120 ? 142.083 163.436 111.189 1.00 24.46  ? 120 LEU B C   1 
ATOM   4622  O O   . LEU B 1 120 ? 141.683 164.052 110.200 1.00 24.46  ? 120 LEU B O   1 
ATOM   4623  C CB  . LEU B 1 120 ? 139.688 163.055 111.810 1.00 24.46  ? 120 LEU B CB  1 
ATOM   4624  C CG  . LEU B 1 120 ? 138.564 162.041 112.029 1.00 24.46  ? 120 LEU B CG  1 
ATOM   4625  C CD1 . LEU B 1 120 ? 137.223 162.667 111.695 1.00 24.46  ? 120 LEU B CD1 1 
ATOM   4626  C CD2 . LEU B 1 120 ? 138.790 160.789 111.202 1.00 24.46  ? 120 LEU B CD2 1 
ATOM   4627  N N   . ASP B 1 121 ? 143.360 163.460 111.565 1.00 26.53  ? 121 ASP B N   1 
ATOM   4628  C CA  . ASP B 1 121 ? 144.346 164.238 110.828 1.00 26.53  ? 121 ASP B CA  1 
ATOM   4629  C C   . ASP B 1 121 ? 144.645 163.579 109.488 1.00 26.53  ? 121 ASP B C   1 
ATOM   4630  O O   . ASP B 1 121 ? 144.926 162.379 109.423 1.00 26.53  ? 121 ASP B O   1 
ATOM   4631  C CB  . ASP B 1 121 ? 145.627 164.380 111.647 1.00 26.53  ? 121 ASP B CB  1 
ATOM   4632  C CG  . ASP B 1 121 ? 146.382 165.656 111.331 1.00 26.53  ? 121 ASP B CG  1 
ATOM   4633  O OD1 . ASP B 1 121 ? 145.755 166.736 111.339 1.00 26.53  ? 121 ASP B OD1 1 
ATOM   4634  O OD2 . ASP B 1 121 ? 147.602 165.581 111.077 1.00 26.53  ? 121 ASP B OD2 1 
ATOM   4635  N N   . PHE B 1 122 ? 144.592 164.368 108.417 1.00 20.05  ? 122 PHE B N   1 
ATOM   4636  C CA  . PHE B 1 122 ? 144.762 163.868 107.059 1.00 20.05  ? 122 PHE B CA  1 
ATOM   4637  C C   . PHE B 1 122 ? 145.844 164.671 106.354 1.00 20.05  ? 122 PHE B C   1 
ATOM   4638  O O   . PHE B 1 122 ? 145.808 165.905 106.359 1.00 20.05  ? 122 PHE B O   1 
ATOM   4639  C CB  . PHE B 1 122 ? 143.442 163.948 106.284 1.00 20.05  ? 122 PHE B CB  1 
ATOM   4640  C CG  . PHE B 1 122 ? 143.491 163.311 104.926 1.00 20.05  ? 122 PHE B CG  1 
ATOM   4641  C CD1 . PHE B 1 122 ? 143.352 161.943 104.783 1.00 20.05  ? 122 PHE B CD1 1 
ATOM   4642  C CD2 . PHE B 1 122 ? 143.655 164.083 103.790 1.00 20.05  ? 122 PHE B CD2 1 
ATOM   4643  C CE1 . PHE B 1 122 ? 143.390 161.358 103.537 1.00 20.05  ? 122 PHE B CE1 1 
ATOM   4644  C CE2 . PHE B 1 122 ? 143.692 163.502 102.542 1.00 20.05  ? 122 PHE B CE2 1 
ATOM   4645  C CZ  . PHE B 1 122 ? 143.559 162.139 102.416 1.00 20.05  ? 122 PHE B CZ  1 
ATOM   4646  N N   . ILE B 1 123 ? 146.797 163.970 105.745 1.00 21.14  ? 123 ILE B N   1 
ATOM   4647  C CA  . ILE B 1 123 ? 147.893 164.586 105.004 1.00 21.14  ? 123 ILE B CA  1 
ATOM   4648  C C   . ILE B 1 123 ? 147.746 164.193 103.541 1.00 21.14  ? 123 ILE B C   1 
ATOM   4649  O O   . ILE B 1 123 ? 147.713 163.001 103.214 1.00 21.14  ? 123 ILE B O   1 
ATOM   4650  C CB  . ILE B 1 123 ? 149.265 164.160 105.548 1.00 21.14  ? 123 ILE B CB  1 
ATOM   4651  C CG1 . ILE B 1 123 ? 149.408 164.539 107.023 1.00 21.14  ? 123 ILE B CG1 1 
ATOM   4652  C CG2 . ILE B 1 123 ? 150.380 164.793 104.732 1.00 21.14  ? 123 ILE B CG2 1 
ATOM   4653  C CD1 . ILE B 1 123 ? 149.322 166.022 107.284 1.00 21.14  ? 123 ILE B CD1 1 
ATOM   4654  N N   . THR B 1 124 ? 147.663 165.191 102.665 1.00 23.45  ? 124 THR B N   1 
ATOM   4655  C CA  . THR B 1 124 ? 147.498 164.942 101.240 1.00 23.45  ? 124 THR B CA  1 
ATOM   4656  C C   . THR B 1 124 ? 148.828 164.552 100.608 1.00 23.45  ? 124 THR B C   1 
ATOM   4657  O O   . THR B 1 124 ? 149.873 165.132 100.913 1.00 23.45  ? 124 THR B O   1 
ATOM   4658  C CB  . THR B 1 124 ? 146.933 166.181 100.544 1.00 23.45  ? 124 THR B CB  1 
ATOM   4659  O OG1 . THR B 1 124 ? 145.749 166.616 101.223 1.00 23.45  ? 124 THR B OG1 1 
ATOM   4660  C CG2 . THR B 1 124 ? 146.585 165.873 99.097  1.00 23.45  ? 124 THR B CG2 1 
ATOM   4661  N N   . GLU B 1 125 ? 148.782 163.563 99.719  1.00 24.67  ? 125 GLU B N   1 
ATOM   4662  C CA  . GLU B 1 125 ? 149.956 163.087 99.006  1.00 24.67  ? 125 GLU B CA  1 
ATOM   4663  C C   . GLU B 1 125 ? 149.727 163.202 97.506  1.00 24.67  ? 125 GLU B C   1 
ATOM   4664  O O   . GLU B 1 125 ? 148.587 163.199 97.034  1.00 24.67  ? 125 GLU B O   1 
ATOM   4665  C CB  . GLU B 1 125 ? 150.287 161.638 99.379  1.00 24.67  ? 125 GLU B CB  1 
ATOM   4666  C CG  . GLU B 1 125 ? 151.006 161.503 100.708 1.00 24.67  ? 125 GLU B CG  1 
ATOM   4667  C CD  . GLU B 1 125 ? 151.298 160.064 101.070 1.00 24.67  ? 125 GLU B CD  1 
ATOM   4668  O OE1 . GLU B 1 125 ? 150.441 159.197 100.806 1.00 24.67  ? 125 GLU B OE1 1 
ATOM   4669  O OE2 . GLU B 1 125 ? 152.388 159.800 101.619 1.00 24.67  ? 125 GLU B OE2 1 
ATOM   4670  N N   . SER B 1 126 ? 150.824 163.307 96.759  1.00 26.14  ? 126 SER B N   1 
ATOM   4671  C CA  . SER B 1 126 ? 150.766 163.570 95.322  1.00 26.14  ? 126 SER B CA  1 
ATOM   4672  C C   . SER B 1 126 ? 150.846 162.249 94.567  1.00 26.14  ? 126 SER B C   1 
ATOM   4673  O O   . SER B 1 126 ? 151.917 161.809 94.148  1.00 26.14  ? 126 SER B O   1 
ATOM   4674  C CB  . SER B 1 126 ? 151.881 164.520 94.906  1.00 26.14  ? 126 SER B CB  1 
ATOM   4675  O OG  . SER B 1 126 ? 153.152 163.991 95.237  1.00 26.14  ? 126 SER B OG  1 
ATOM   4676  N N   . PHE B 1 127 ? 149.695 161.607 94.394  1.00 25.89  ? 127 PHE B N   1 
ATOM   4677  C CA  . PHE B 1 127 ? 149.602 160.430 93.543  1.00 25.89  ? 127 PHE B CA  1 
ATOM   4678  C C   . PHE B 1 127 ? 149.444 160.853 92.090  1.00 25.89  ? 127 PHE B C   1 
ATOM   4679  O O   . PHE B 1 127 ? 148.759 161.833 91.784  1.00 25.89  ? 127 PHE B O   1 
ATOM   4680  C CB  . PHE B 1 127 ? 148.420 159.554 93.956  1.00 25.89  ? 127 PHE B CB  1 
ATOM   4681  C CG  . PHE B 1 127 ? 148.563 158.930 95.313  1.00 25.89  ? 127 PHE B CG  1 
ATOM   4682  C CD1 . PHE B 1 127 ? 149.211 157.718 95.468  1.00 25.89  ? 127 PHE B CD1 1 
ATOM   4683  C CD2 . PHE B 1 127 ? 148.027 159.544 96.431  1.00 25.89  ? 127 PHE B CD2 1 
ATOM   4684  C CE1 . PHE B 1 127 ? 149.334 157.138 96.713  1.00 25.89  ? 127 PHE B CE1 1 
ATOM   4685  C CE2 . PHE B 1 127 ? 148.147 158.968 97.678  1.00 25.89  ? 127 PHE B CE2 1 
ATOM   4686  C CZ  . PHE B 1 127 ? 148.800 157.764 97.819  1.00 25.89  ? 127 PHE B CZ  1 
ATOM   4687  N N   . THR B 1 128 ? 150.080 160.107 91.191  1.00 28.65  ? 128 THR B N   1 
ATOM   4688  C CA  . THR B 1 128 ? 150.014 160.374 89.759  1.00 28.65  ? 128 THR B CA  1 
ATOM   4689  C C   . THR B 1 128 ? 149.264 159.238 89.082  1.00 28.65  ? 128 THR B C   1 
ATOM   4690  O O   . THR B 1 128 ? 149.699 158.083 89.137  1.00 28.65  ? 128 THR B O   1 
ATOM   4691  C CB  . THR B 1 128 ? 151.412 160.525 89.158  1.00 28.65  ? 128 THR B CB  1 
ATOM   4692  O OG1 . THR B 1 128 ? 152.190 161.412 89.970  1.00 28.65  ? 128 THR B OG1 1 
ATOM   4693  C CG2 . THR B 1 128 ? 151.325 161.084 87.747  1.00 28.65  ? 128 THR B CG2 1 
ATOM   4694  N N   . TRP B 1 129 ? 148.143 159.566 88.443  1.00 26.63  ? 129 TRP B N   1 
ATOM   4695  C CA  . TRP B 1 129 ? 147.331 158.602 87.709  1.00 26.63  ? 129 TRP B CA  1 
ATOM   4696  C C   . TRP B 1 129 ? 147.349 159.001 86.240  1.00 26.63  ? 129 TRP B C   1 
ATOM   4697  O O   . TRP B 1 129 ? 146.695 159.974 85.849  1.00 26.63  ? 129 TRP B O   1 
ATOM   4698  C CB  . TRP B 1 129 ? 145.906 158.553 88.257  1.00 26.63  ? 129 TRP B CB  1 
ATOM   4699  C CG  . TRP B 1 129 ? 145.845 158.533 89.754  1.00 26.63  ? 129 TRP B CG  1 
ATOM   4700  C CD1 . TRP B 1 129 ? 145.512 159.569 90.574  1.00 26.63  ? 129 TRP B CD1 1 
ATOM   4701  C CD2 . TRP B 1 129 ? 146.132 157.420 90.610  1.00 26.63  ? 129 TRP B CD2 1 
ATOM   4702  N NE1 . TRP B 1 129 ? 145.570 159.171 91.887  1.00 26.63  ? 129 TRP B NE1 1 
ATOM   4703  C CE2 . TRP B 1 129 ? 145.949 157.856 91.935  1.00 26.63  ? 129 TRP B CE2 1 
ATOM   4704  C CE3 . TRP B 1 129 ? 146.523 156.098 90.383  1.00 26.63  ? 129 TRP B CE3 1 
ATOM   4705  C CZ2 . TRP B 1 129 ? 146.145 157.018 93.029  1.00 26.63  ? 129 TRP B CZ2 1 
ATOM   4706  C CZ3 . TRP B 1 129 ? 146.716 155.269 91.470  1.00 26.63  ? 129 TRP B CZ3 1 
ATOM   4707  C CH2 . TRP B 1 129 ? 146.526 155.731 92.776  1.00 26.63  ? 129 TRP B CH2 1 
ATOM   4708  N N   . ALA B 1 130 ? 148.093 158.252 85.432  1.00 29.97  ? 130 ALA B N   1 
ATOM   4709  C CA  . ALA B 1 130 ? 148.335 158.597 84.039  1.00 29.97  ? 130 ALA B CA  1 
ATOM   4710  C C   . ALA B 1 130 ? 147.352 157.868 83.134  1.00 29.97  ? 130 ALA B C   1 
ATOM   4711  O O   . ALA B 1 130 ? 147.132 156.663 83.290  1.00 29.97  ? 130 ALA B O   1 
ATOM   4712  C CB  . ALA B 1 130 ? 149.771 158.254 83.640  1.00 29.97  ? 130 ALA B CB  1 
ATOM   4713  N N   . GLY B 1 131 ? 146.767 158.602 82.190  1.00 30.53  ? 131 GLY B N   1 
ATOM   4714  C CA  . GLY B 1 131 ? 145.882 158.017 81.206  1.00 30.53  ? 131 GLY B CA  1 
ATOM   4715  C C   . GLY B 1 131 ? 144.443 157.854 81.632  1.00 30.53  ? 131 GLY B C   1 
ATOM   4716  O O   . GLY B 1 131 ? 143.662 157.250 80.889  1.00 30.53  ? 131 GLY B O   1 
ATOM   4717  N N   . VAL B 1 132 ? 144.061 158.370 82.801  1.00 28.74  ? 132 VAL B N   1 
ATOM   4718  C CA  . VAL B 1 132 ? 142.695 158.270 83.292  1.00 28.74  ? 132 VAL B CA  1 
ATOM   4719  C C   . VAL B 1 132 ? 142.213 159.658 83.691  1.00 28.74  ? 132 VAL B C   1 
ATOM   4720  O O   . VAL B 1 132 ? 143.001 160.586 83.883  1.00 28.74  ? 132 VAL B O   1 
ATOM   4721  C CB  . VAL B 1 132 ? 142.565 157.297 84.483  1.00 28.74  ? 132 VAL B CB  1 
ATOM   4722  C CG1 . VAL B 1 132 ? 142.814 155.866 84.034  1.00 28.74  ? 132 VAL B CG1 1 
ATOM   4723  C CG2 . VAL B 1 132 ? 143.521 157.688 85.594  1.00 28.74  ? 132 VAL B CG2 1 
ATOM   4724  N N   . SER B 1 133 ? 140.895 159.789 83.809  1.00 27.94  ? 133 SER B N   1 
ATOM   4725  C CA  . SER B 1 133 ? 140.266 161.022 84.257  1.00 27.94  ? 133 SER B CA  1 
ATOM   4726  C C   . SER B 1 133 ? 139.887 160.897 85.726  1.00 27.94  ? 133 SER B C   1 
ATOM   4727  O O   . SER B 1 133 ? 139.400 159.852 86.166  1.00 27.94  ? 133 SER B O   1 
ATOM   4728  C CB  . SER B 1 133 ? 139.030 161.347 83.417  1.00 27.94  ? 133 SER B CB  1 
ATOM   4729  O OG  . SER B 1 133 ? 138.158 160.236 83.343  1.00 27.94  ? 133 SER B OG  1 
ATOM   4730  N N   . GLN B 1 134 ? 140.115 161.966 86.480  1.00 26.26  ? 134 GLN B N   1 
ATOM   4731  C CA  . GLN B 1 134 ? 139.960 161.965 87.927  1.00 26.26  ? 134 GLN B CA  1 
ATOM   4732  C C   . GLN B 1 134 ? 138.763 162.809 88.345  1.00 26.26  ? 134 GLN B C   1 
ATOM   4733  O O   . GLN B 1 134 ? 138.118 163.473 87.530  1.00 26.26  ? 134 GLN B O   1 
ATOM   4734  C CB  . GLN B 1 134 ? 141.231 162.488 88.604  1.00 26.26  ? 134 GLN B CB  1 
ATOM   4735  C CG  . GLN B 1 134 ? 142.520 162.013 87.964  1.00 26.26  ? 134 GLN B CG  1 
ATOM   4736  C CD  . GLN B 1 134 ? 143.745 162.513 88.698  1.00 26.26  ? 134 GLN B CD  1 
ATOM   4737  O OE1 . GLN B 1 134 ? 143.645 163.050 89.800  1.00 26.26  ? 134 GLN B OE1 1 
ATOM   4738  N NE2 . GLN B 1 134 ? 144.910 162.345 88.086  1.00 26.26  ? 134 GLN B NE2 1 
ATOM   4739  N N   . ASN B 1 135 ? 138.476 162.763 89.648  1.00 25.64  ? 135 ASN B N   1 
ATOM   4740  C CA  . ASN B 1 135 ? 137.449 163.589 90.283  1.00 25.64  ? 135 ASN B CA  1 
ATOM   4741  C C   . ASN B 1 135 ? 136.065 163.322 89.687  1.00 25.64  ? 135 ASN B C   1 
ATOM   4742  O O   . ASN B 1 135 ? 135.415 164.205 89.124  1.00 25.64  ? 135 ASN B O   1 
ATOM   4743  C CB  . ASN B 1 135 ? 137.814 165.075 90.197  1.00 25.64  ? 135 ASN B CB  1 
ATOM   4744  C CG  . ASN B 1 135 ? 139.155 165.383 90.833  1.00 25.64  ? 135 ASN B CG  1 
ATOM   4745  O OD1 . ASN B 1 135 ? 139.412 165.010 91.976  1.00 25.64  ? 135 ASN B OD1 1 
ATOM   4746  N ND2 . ASN B 1 135 ? 140.018 166.068 90.094  1.00 25.64  ? 135 ASN B ND2 1 
ATOM   4747  N N   . GLY B 1 136 ? 135.619 162.076 89.828  1.00 25.41  ? 136 GLY B N   1 
ATOM   4748  C CA  . GLY B 1 136 ? 134.280 161.719 89.405  1.00 25.41  ? 136 GLY B CA  1 
ATOM   4749  C C   . GLY B 1 136 ? 133.259 161.935 90.508  1.00 25.41  ? 136 GLY B C   1 
ATOM   4750  O O   . GLY B 1 136 ? 133.560 161.849 91.697  1.00 25.41  ? 136 GLY B O   1 
ATOM   4751  N N   . GLY B 1 137 ? 132.022 162.219 90.097  1.00 26.73  ? 137 GLY B N   1 
ATOM   4752  C CA  . GLY B 1 137 ? 130.959 162.519 91.032  1.00 26.73  ? 137 GLY B CA  1 
ATOM   4753  C C   . GLY B 1 137 ? 129.659 161.853 90.630  1.00 26.73  ? 137 GLY B C   1 
ATOM   4754  O O   . GLY B 1 137 ? 129.580 161.159 89.616  1.00 26.73  ? 137 GLY B O   1 
ATOM   4755  N N   . SER B 1 138 ? 128.636 162.082 91.451  1.00 28.29  ? 138 SER B N   1 
ATOM   4756  C CA  . SER B 1 138 ? 127.324 161.496 91.229  1.00 28.29  ? 138 SER B CA  1 
ATOM   4757  C C   . SER B 1 138 ? 126.263 162.412 91.818  1.00 28.29  ? 138 SER B C   1 
ATOM   4758  O O   . SER B 1 138 ? 126.551 163.265 92.661  1.00 28.29  ? 138 SER B O   1 
ATOM   4759  C CB  . SER B 1 138 ? 127.221 160.096 91.846  1.00 28.29  ? 138 SER B CB  1 
ATOM   4760  O OG  . SER B 1 138 ? 126.013 159.461 91.470  1.00 28.29  ? 138 SER B OG  1 
ATOM   4761  N N   . SER B 1 139 ? 125.025 162.227 91.360  1.00 28.31  ? 139 SER B N   1 
ATOM   4762  C CA  . SER B 1 139 ? 123.902 162.991 91.888  1.00 28.31  ? 139 SER B CA  1 
ATOM   4763  C C   . SER B 1 139 ? 123.455 162.510 93.261  1.00 28.31  ? 139 SER B C   1 
ATOM   4764  O O   . SER B 1 139 ? 122.702 163.221 93.933  1.00 28.31  ? 139 SER B O   1 
ATOM   4765  C CB  . SER B 1 139 ? 122.721 162.935 90.917  1.00 28.31  ? 139 SER B CB  1 
ATOM   4766  O OG  . SER B 1 139 ? 122.184 161.627 90.841  1.00 28.31  ? 139 SER B OG  1 
ATOM   4767  N N   . ALA B 1 140 ? 123.895 161.326 93.690  1.00 28.05  ? 140 ALA B N   1 
ATOM   4768  C CA  . ALA B 1 140 ? 123.607 160.851 95.036  1.00 28.05  ? 140 ALA B CA  1 
ATOM   4769  C C   . ALA B 1 140 ? 124.436 161.561 96.095  1.00 28.05  ? 140 ALA B C   1 
ATOM   4770  O O   . ALA B 1 140 ? 124.164 161.392 97.288  1.00 28.05  ? 140 ALA B O   1 
ATOM   4771  C CB  . ALA B 1 140 ? 123.843 159.343 95.123  1.00 28.05  ? 140 ALA B CB  1 
ATOM   4772  N N   . CYS B 1 141 ? 125.430 162.349 95.690  1.00 29.89  ? 141 CYS B N   1 
ATOM   4773  C CA  . CYS B 1 141 ? 126.329 163.037 96.615  1.00 29.89  ? 141 CYS B CA  1 
ATOM   4774  C C   . CYS B 1 141 ? 126.547 164.438 96.051  1.00 29.89  ? 141 CYS B C   1 
ATOM   4775  O O   . CYS B 1 141 ? 127.288 164.612 95.081  1.00 29.89  ? 141 CYS B O   1 
ATOM   4776  C CB  . CYS B 1 141 ? 127.641 162.275 96.763  1.00 29.89  ? 141 CYS B CB  1 
ATOM   4777  S SG  . CYS B 1 141 ? 128.554 162.603 98.280  1.00 29.89  ? 141 CYS B SG  1 
ATOM   4778  N N   . LYS B 1 142 ? 125.894 165.430 96.650  1.00 33.03  ? 142 LYS B N   1 
ATOM   4779  C CA  . LYS B 1 142 ? 125.875 166.787 96.119  1.00 33.03  ? 142 LYS B CA  1 
ATOM   4780  C C   . LYS B 1 142 ? 126.725 167.715 96.977  1.00 33.03  ? 142 LYS B C   1 
ATOM   4781  O O   . LYS B 1 142 ? 126.569 167.754 98.202  1.00 33.03  ? 142 LYS B O   1 
ATOM   4782  C CB  . LYS B 1 142 ? 124.443 167.317 96.044  1.00 33.03  ? 142 LYS B CB  1 
ATOM   4783  C CG  . LYS B 1 142 ? 123.502 166.462 95.218  1.00 33.03  ? 142 LYS B CG  1 
ATOM   4784  C CD  . LYS B 1 142 ? 123.795 166.592 93.735  1.00 33.03  ? 142 LYS B CD  1 
ATOM   4785  C CE  . LYS B 1 142 ? 123.252 167.897 93.182  1.00 33.03  ? 142 LYS B CE  1 
ATOM   4786  N NZ  . LYS B 1 142 ? 123.308 167.932 91.695  1.00 33.03  ? 142 LYS B NZ  1 
ATOM   4787  N N   . ARG B 1 143 ? 127.616 168.460 96.330  1.00 34.08  ? 143 ARG B N   1 
ATOM   4788  C CA  . ARG B 1 143 ? 128.370 169.547 96.953  1.00 34.08  ? 143 ARG B CA  1 
ATOM   4789  C C   . ARG B 1 143 ? 127.718 170.855 96.512  1.00 34.08  ? 143 ARG B C   1 
ATOM   4790  O O   . ARG B 1 143 ? 128.136 171.476 95.533  1.00 34.08  ? 143 ARG B O   1 
ATOM   4791  C CB  . ARG B 1 143 ? 129.847 169.503 96.567  1.00 34.08  ? 143 ARG B CB  1 
ATOM   4792  C CG  . ARG B 1 143 ? 130.571 168.241 96.985  1.00 34.08  ? 143 ARG B CG  1 
ATOM   4793  C CD  . ARG B 1 143 ? 130.699 168.186 98.495  1.00 34.08  ? 143 ARG B CD  1 
ATOM   4794  N NE  . ARG B 1 143 ? 131.379 166.982 98.953  1.00 34.08  ? 143 ARG B NE  1 
ATOM   4795  C CZ  . ARG B 1 143 ? 132.688 166.879 99.128  1.00 34.08  ? 143 ARG B CZ  1 
ATOM   4796  N NH1 . ARG B 1 143 ? 133.497 167.897 98.893  1.00 34.08  ? 143 ARG B NH1 1 
ATOM   4797  N NH2 . ARG B 1 143 ? 133.196 165.728 99.556  1.00 34.08  ? 143 ARG B NH2 1 
ATOM   4798  N N   . GLY B 1 144 ? 126.691 171.271 97.244  1.00 37.33  ? 144 GLY B N   1 
ATOM   4799  C CA  . GLY B 1 144 ? 125.936 172.447 96.890  1.00 37.33  ? 144 GLY B CA  1 
ATOM   4800  C C   . GLY B 1 144 ? 125.012 172.188 95.718  1.00 37.33  ? 144 GLY B C   1 
ATOM   4801  O O   . GLY B 1 144 ? 124.100 171.359 95.788  1.00 37.33  ? 144 GLY B O   1 
ATOM   4802  N N   . PRO B 1 145 ? 125.227 172.903 94.614  1.00 39.84  ? 145 PRO B N   1 
ATOM   4803  C CA  . PRO B 1 145 ? 124.384 172.698 93.430  1.00 39.84  ? 145 PRO B CA  1 
ATOM   4804  C C   . PRO B 1 145 ? 124.918 171.631 92.485  1.00 39.84  ? 145 PRO B C   1 
ATOM   4805  O O   . PRO B 1 145 ? 124.180 171.130 91.632  1.00 39.84  ? 145 PRO B O   1 
ATOM   4806  C CB  . PRO B 1 145 ? 124.386 174.080 92.767  1.00 39.84  ? 145 PRO B CB  1 
ATOM   4807  C CG  . PRO B 1 145 ? 125.713 174.670 93.145  1.00 39.84  ? 145 PRO B CG  1 
ATOM   4808  C CD  . PRO B 1 145 ? 126.170 174.022 94.436  1.00 39.84  ? 145 PRO B CD  1 
ATOM   4809  N N   . ALA B 1 146 ? 126.190 171.274 92.626  1.00 34.91  ? 146 ALA B N   1 
ATOM   4810  C CA  . ALA B 1 146 ? 126.860 170.382 91.692  1.00 34.91  ? 146 ALA B CA  1 
ATOM   4811  C C   . ALA B 1 146 ? 127.049 168.992 92.289  1.00 34.91  ? 146 ALA B C   1 
ATOM   4812  O O   . ALA B 1 146 ? 126.957 168.787 93.501  1.00 34.91  ? 146 ALA B O   1 
ATOM   4813  C CB  . ALA B 1 146 ? 128.216 170.958 91.278  1.00 34.91  ? 146 ALA B CB  1 
ATOM   4814  N N   . ASN B 1 147 ? 127.315 168.031 91.407  1.00 31.68  ? 147 ASN B N   1 
ATOM   4815  C CA  . ASN B 1 147 ? 127.554 166.658 91.828  1.00 31.68  ? 147 ASN B CA  1 
ATOM   4816  C C   . ASN B 1 147 ? 128.913 166.535 92.503  1.00 31.68  ? 147 ASN B C   1 
ATOM   4817  O O   . ASN B 1 147 ? 129.881 167.193 92.113  1.00 31.68  ? 147 ASN B O   1 
ATOM   4818  C CB  . ASN B 1 147 ? 127.481 165.716 90.627  1.00 31.68  ? 147 ASN B CB  1 
ATOM   4819  C CG  . ASN B 1 147 ? 126.094 165.650 90.021  1.00 31.68  ? 147 ASN B CG  1 
ATOM   4820  O OD1 . ASN B 1 147 ? 125.141 166.208 90.561  1.00 31.68  ? 147 ASN B OD1 1 
ATOM   4821  N ND2 . ASN B 1 147 ? 125.976 164.966 88.890  1.00 31.68  ? 147 ASN B ND2 1 
ATOM   4822  N N   . GLY B 1 148 ? 128.986 165.681 93.520  1.00 27.70  ? 148 GLY B N   1 
ATOM   4823  C CA  . GLY B 1 148 ? 130.222 165.507 94.256  1.00 27.70  ? 148 GLY B CA  1 
ATOM   4824  C C   . GLY B 1 148 ? 130.532 164.072 94.625  1.00 27.70  ? 148 GLY B C   1 
ATOM   4825  O O   . GLY B 1 148 ? 129.952 163.135 94.070  1.00 27.70  ? 148 GLY B O   1 
ATOM   4826  N N   . PHE B 1 149 ? 131.449 163.894 95.569  1.00 23.02  ? 149 PHE B N   1 
ATOM   4827  C CA  . PHE B 1 149 ? 131.884 162.578 96.017  1.00 23.02  ? 149 PHE B CA  1 
ATOM   4828  C C   . PHE B 1 149 ? 132.507 162.743 97.397  1.00 23.02  ? 149 PHE B C   1 
ATOM   4829  O O   . PHE B 1 149 ? 132.514 163.837 97.966  1.00 23.02  ? 149 PHE B O   1 
ATOM   4830  C CB  . PHE B 1 149 ? 132.863 161.956 95.015  1.00 23.02  ? 149 PHE B CB  1 
ATOM   4831  C CG  . PHE B 1 149 ? 132.961 160.459 95.100  1.00 23.02  ? 149 PHE B CG  1 
ATOM   4832  C CD1 . PHE B 1 149 ? 131.831 159.668 95.000  1.00 23.02  ? 149 PHE B CD1 1 
ATOM   4833  C CD2 . PHE B 1 149 ? 134.191 159.843 95.268  1.00 23.02  ? 149 PHE B CD2 1 
ATOM   4834  C CE1 . PHE B 1 149 ? 131.924 158.292 95.074  1.00 23.02  ? 149 PHE B CE1 1 
ATOM   4835  C CE2 . PHE B 1 149 ? 134.290 158.469 95.342  1.00 23.02  ? 149 PHE B CE2 1 
ATOM   4836  C CZ  . PHE B 1 149 ? 133.156 157.693 95.245  1.00 23.02  ? 149 PHE B CZ  1 
ATOM   4837  N N   . PHE B 1 150 ? 133.022 161.642 97.940  1.00 21.42  ? 150 PHE B N   1 
ATOM   4838  C CA  . PHE B 1 150 ? 133.758 161.714 99.194  1.00 21.42  ? 150 PHE B CA  1 
ATOM   4839  C C   . PHE B 1 150 ? 135.015 162.556 99.013  1.00 21.42  ? 150 PHE B C   1 
ATOM   4840  O O   . PHE B 1 150 ? 135.692 162.477 97.985  1.00 21.42  ? 150 PHE B O   1 
ATOM   4841  C CB  . PHE B 1 150 ? 134.123 160.312 99.678  1.00 21.42  ? 150 PHE B CB  1 
ATOM   4842  C CG  . PHE B 1 150 ? 132.937 159.440 99.967  1.00 21.42  ? 150 PHE B CG  1 
ATOM   4843  C CD1 . PHE B 1 150 ? 132.221 159.589 101.141 1.00 21.42  ? 150 PHE B CD1 1 
ATOM   4844  C CD2 . PHE B 1 150 ? 132.541 158.467 99.067  1.00 21.42  ? 150 PHE B CD2 1 
ATOM   4845  C CE1 . PHE B 1 150 ? 131.132 158.786 101.411 1.00 21.42  ? 150 PHE B CE1 1 
ATOM   4846  C CE2 . PHE B 1 150 ? 131.452 157.661 99.331  1.00 21.42  ? 150 PHE B CE2 1 
ATOM   4847  C CZ  . PHE B 1 150 ? 130.747 157.821 100.504 1.00 21.42  ? 150 PHE B CZ  1 
ATOM   4848  N N   . SER B 1 151 ? 135.324 163.372 100.021 1.00 22.77  ? 151 SER B N   1 
ATOM   4849  C CA  . SER B 1 151 ? 136.433 164.311 99.907  1.00 22.77  ? 151 SER B CA  1 
ATOM   4850  C C   . SER B 1 151 ? 137.797 163.648 100.045 1.00 22.77  ? 151 SER B C   1 
ATOM   4851  O O   . SER B 1 151 ? 138.792 164.215 99.582  1.00 22.77  ? 151 SER B O   1 
ATOM   4852  C CB  . SER B 1 151 ? 136.294 165.419 100.953 1.00 22.77  ? 151 SER B CB  1 
ATOM   4853  O OG  . SER B 1 151 ? 136.590 164.939 102.251 1.00 22.77  ? 151 SER B OG  1 
ATOM   4854  N N   . ARG B 1 152 ? 137.870 162.470 100.660 1.00 21.11  ? 152 ARG B N   1 
ATOM   4855  C CA  . ARG B 1 152 ? 139.135 161.782 100.876 1.00 21.11  ? 152 ARG B CA  1 
ATOM   4856  C C   . ARG B 1 152 ? 139.376 160.657 99.878  1.00 21.11  ? 152 ARG B C   1 
ATOM   4857  O O   . ARG B 1 152 ? 140.347 159.909 100.028 1.00 21.11  ? 152 ARG B O   1 
ATOM   4858  C CB  . ARG B 1 152 ? 139.202 161.234 102.303 1.00 21.11  ? 152 ARG B CB  1 
ATOM   4859  C CG  . ARG B 1 152 ? 138.956 162.272 103.383 1.00 21.11  ? 152 ARG B CG  1 
ATOM   4860  C CD  . ARG B 1 152 ? 139.867 163.469 103.215 1.00 21.11  ? 152 ARG B CD  1 
ATOM   4861  N NE  . ARG B 1 152 ? 139.987 164.242 104.444 1.00 21.11  ? 152 ARG B NE  1 
ATOM   4862  C CZ  . ARG B 1 152 ? 140.379 165.507 104.497 1.00 21.11  ? 152 ARG B CZ  1 
ATOM   4863  N NH1 . ARG B 1 152 ? 140.684 166.182 103.401 1.00 21.11  ? 152 ARG B NH1 1 
ATOM   4864  N NH2 . ARG B 1 152 ? 140.472 166.109 105.678 1.00 21.11  ? 152 ARG B NH2 1 
ATOM   4865  N N   . LEU B 1 153 ? 138.524 160.520 98.865  1.00 19.99  ? 153 LEU B N   1 
ATOM   4866  C CA  . LEU B 1 153 ? 138.639 159.453 97.884  1.00 19.99  ? 153 LEU B CA  1 
ATOM   4867  C C   . LEU B 1 153 ? 138.557 160.032 96.479  1.00 19.99  ? 153 LEU B C   1 
ATOM   4868  O O   . LEU B 1 153 ? 137.912 161.057 96.249  1.00 19.99  ? 153 LEU B O   1 
ATOM   4869  C CB  . LEU B 1 153 ? 137.546 158.393 98.078  1.00 19.99  ? 153 LEU B CB  1 
ATOM   4870  C CG  . LEU B 1 153 ? 137.539 157.648 99.414  1.00 19.99  ? 153 LEU B CG  1 
ATOM   4871  C CD1 . LEU B 1 153 ? 136.148 157.125 99.724  1.00 19.99  ? 153 LEU B CD1 1 
ATOM   4872  C CD2 . LEU B 1 153 ? 138.550 156.514 99.410  1.00 19.99  ? 153 LEU B CD2 1 
ATOM   4873  N N   . ASN B 1 154 ? 139.221 159.361 95.539  1.00 21.73  ? 154 ASN B N   1 
ATOM   4874  C CA  . ASN B 1 154 ? 139.288 159.792 94.148  1.00 21.73  ? 154 ASN B CA  1 
ATOM   4875  C C   . ASN B 1 154 ? 138.686 158.710 93.264  1.00 21.73  ? 154 ASN B C   1 
ATOM   4876  O O   . ASN B 1 154 ? 139.120 157.554 93.311  1.00 21.73  ? 154 ASN B O   1 
ATOM   4877  C CB  . ASN B 1 154 ? 140.734 160.082 93.738  1.00 21.73  ? 154 ASN B CB  1 
ATOM   4878  C CG  . ASN B 1 154 ? 140.829 160.990 92.531  1.00 21.73  ? 154 ASN B CG  1 
ATOM   4879  O OD1 . ASN B 1 154 ? 139.820 161.362 91.939  1.00 21.73  ? 154 ASN B OD1 1 
ATOM   4880  N ND2 . ASN B 1 154 ? 142.049 161.355 92.162  1.00 21.73  ? 154 ASN B ND2 1 
ATOM   4881  N N   . TRP B 1 155 ? 137.693 159.084 92.459  1.00 24.23  ? 155 TRP B N   1 
ATOM   4882  C CA  . TRP B 1 155 ? 137.016 158.162 91.553  1.00 24.23  ? 155 TRP B CA  1 
ATOM   4883  C C   . TRP B 1 155 ? 137.659 158.280 90.175  1.00 24.23  ? 155 TRP B C   1 
ATOM   4884  O O   . TRP B 1 155 ? 137.490 159.292 89.489  1.00 24.23  ? 155 TRP B O   1 
ATOM   4885  C CB  . TRP B 1 155 ? 135.519 158.465 91.494  1.00 24.23  ? 155 TRP B CB  1 
ATOM   4886  C CG  . TRP B 1 155 ? 134.690 157.379 90.869  1.00 24.23  ? 155 TRP B CG  1 
ATOM   4887  C CD1 . TRP B 1 155 ? 135.143 156.272 90.213  1.00 24.23  ? 155 TRP B CD1 1 
ATOM   4888  C CD2 . TRP B 1 155 ? 133.259 157.300 90.843  1.00 24.23  ? 155 TRP B CD2 1 
ATOM   4889  N NE1 . TRP B 1 155 ? 134.087 155.511 89.780  1.00 24.23  ? 155 TRP B NE1 1 
ATOM   4890  C CE2 . TRP B 1 155 ? 132.919 156.120 90.154  1.00 24.23  ? 155 TRP B CE2 1 
ATOM   4891  C CE3 . TRP B 1 155 ? 132.234 158.113 91.335  1.00 24.23  ? 155 TRP B CE3 1 
ATOM   4892  C CZ2 . TRP B 1 155 ? 131.597 155.732 89.947  1.00 24.23  ? 155 TRP B CZ2 1 
ATOM   4893  C CZ3 . TRP B 1 155 ? 130.923 157.726 91.127  1.00 24.23  ? 155 TRP B CZ3 1 
ATOM   4894  C CH2 . TRP B 1 155 ? 130.617 156.547 90.440  1.00 24.23  ? 155 TRP B CH2 1 
ATOM   4895  N N   . LEU B 1 156 ? 138.386 157.243 89.770  1.00 25.35  ? 156 LEU B N   1 
ATOM   4896  C CA  . LEU B 1 156 ? 139.113 157.237 88.508  1.00 25.35  ? 156 LEU B CA  1 
ATOM   4897  C C   . LEU B 1 156 ? 138.309 156.513 87.437  1.00 25.35  ? 156 LEU B C   1 
ATOM   4898  O O   . LEU B 1 156 ? 137.801 155.411 87.663  1.00 25.35  ? 156 LEU B O   1 
ATOM   4899  C CB  . LEU B 1 156 ? 140.481 156.573 88.670  1.00 25.35  ? 156 LEU B CB  1 
ATOM   4900  C CG  . LEU B 1 156 ? 141.383 157.104 89.785  1.00 25.35  ? 156 LEU B CG  1 
ATOM   4901  C CD1 . LEU B 1 156 ? 142.599 156.212 89.945  1.00 25.35  ? 156 LEU B CD1 1 
ATOM   4902  C CD2 . LEU B 1 156 ? 141.802 158.535 89.503  1.00 25.35  ? 156 LEU B CD2 1 
ATOM   4903  N N   . THR B 1 157 ? 138.207 157.138 86.266  1.00 29.45  ? 157 THR B N   1 
ATOM   4904  C CA  . THR B 1 157 ? 137.432 156.610 85.154  1.00 29.45  ? 157 THR B CA  1 
ATOM   4905  C C   . THR B 1 157 ? 138.280 156.716 83.892  1.00 29.45  ? 157 THR B C   1 
ATOM   4906  O O   . THR B 1 157 ? 139.309 157.394 83.871  1.00 29.45  ? 157 THR B O   1 
ATOM   4907  C CB  . THR B 1 157 ? 136.098 157.366 85.000  1.00 29.45  ? 157 THR B CB  1 
ATOM   4908  O OG1 . THR B 1 157 ? 135.494 157.527 86.288  1.00 29.45  ? 157 THR B OG1 1 
ATOM   4909  C CG2 . THR B 1 157 ? 135.124 156.600 84.121  1.00 29.45  ? 157 THR B CG2 1 
ATOM   4910  N N   . LYS B 1 158 ? 137.846 156.025 82.840  1.00 31.70  ? 158 LYS B N   1 
ATOM   4911  C CA  . LYS B 1 158 ? 138.599 156.000 81.594  1.00 31.70  ? 158 LYS B CA  1 
ATOM   4912  C C   . LYS B 1 158 ? 138.696 157.396 80.987  1.00 31.70  ? 158 LYS B C   1 
ATOM   4913  O O   . LYS B 1 158 ? 137.799 158.230 81.131  1.00 31.70  ? 158 LYS B O   1 
ATOM   4914  C CB  . LYS B 1 158 ? 137.948 155.036 80.599  1.00 31.70  ? 158 LYS B CB  1 
ATOM   4915  C CG  . LYS B 1 158 ? 136.754 155.615 79.860  1.00 31.70  ? 158 LYS B CG  1 
ATOM   4916  C CD  . LYS B 1 158 ? 136.290 154.708 78.738  1.00 31.70  ? 158 LYS B CD  1 
ATOM   4917  C CE  . LYS B 1 158 ? 135.056 155.276 78.060  1.00 31.70  ? 158 LYS B CE  1 
ATOM   4918  N NZ  . LYS B 1 158 ? 134.510 154.351 77.031  1.00 31.70  ? 158 LYS B NZ  1 
ATOM   4919  N N   . SER B 1 159 ? 139.817 157.651 80.318  1.00 33.70  ? 159 SER B N   1 
ATOM   4920  C CA  . SER B 1 159 ? 140.062 158.905 79.618  1.00 33.70  ? 159 SER B CA  1 
ATOM   4921  C C   . SER B 1 159 ? 140.004 158.636 78.122  1.00 33.70  ? 159 SER B C   1 
ATOM   4922  O O   . SER B 1 159 ? 140.721 157.765 77.618  1.00 33.70  ? 159 SER B O   1 
ATOM   4923  C CB  . SER B 1 159 ? 141.414 159.500 80.007  1.00 33.70  ? 159 SER B CB  1 
ATOM   4924  O OG  . SER B 1 159 ? 141.667 160.698 79.296  1.00 33.70  ? 159 SER B OG  1 
ATOM   4925  N N   . GLY B 1 160 ? 139.160 159.382 77.418  1.00 35.62  ? 160 GLY B N   1 
ATOM   4926  C CA  . GLY B 1 160 ? 138.953 159.124 76.009  1.00 35.62  ? 160 GLY B CA  1 
ATOM   4927  C C   . GLY B 1 160 ? 138.258 157.799 75.786  1.00 35.62  ? 160 GLY B C   1 
ATOM   4928  O O   . GLY B 1 160 ? 137.059 157.666 76.051  1.00 35.62  ? 160 GLY B O   1 
ATOM   4929  N N   . SER B 1 161 ? 139.003 156.804 75.300  1.00 35.90  ? 161 SER B N   1 
ATOM   4930  C CA  . SER B 1 161 ? 138.452 155.477 75.054  1.00 35.90  ? 161 SER B CA  1 
ATOM   4931  C C   . SER B 1 161 ? 139.357 154.370 75.584  1.00 35.90  ? 161 SER B C   1 
ATOM   4932  O O   . SER B 1 161 ? 139.258 153.228 75.126  1.00 35.90  ? 161 SER B O   1 
ATOM   4933  C CB  . SER B 1 161 ? 138.192 155.271 73.560  1.00 35.90  ? 161 SER B CB  1 
ATOM   4934  O OG  . SER B 1 161 ? 139.371 154.858 72.892  1.00 35.90  ? 161 SER B OG  1 
ATOM   4935  N N   . SER B 1 162 ? 140.235 154.677 76.537  1.00 33.19  ? 162 SER B N   1 
ATOM   4936  C CA  . SER B 1 162 ? 141.181 153.696 77.047  1.00 33.19  ? 162 SER B CA  1 
ATOM   4937  C C   . SER B 1 162 ? 141.316 153.836 78.556  1.00 33.19  ? 162 SER B C   1 
ATOM   4938  O O   . SER B 1 162 ? 141.164 154.925 79.113  1.00 33.19  ? 162 SER B O   1 
ATOM   4939  C CB  . SER B 1 162 ? 142.556 153.846 76.383  1.00 33.19  ? 162 SER B CB  1 
ATOM   4940  O OG  . SER B 1 162 ? 143.101 155.131 76.624  1.00 33.19  ? 162 SER B OG  1 
ATOM   4941  N N   . TYR B 1 163 ? 141.602 152.712 79.209  1.00 28.19  ? 163 TYR B N   1 
ATOM   4942  C CA  . TYR B 1 163 ? 141.889 152.669 80.642  1.00 28.19  ? 163 TYR B CA  1 
ATOM   4943  C C   . TYR B 1 163 ? 143.177 151.878 80.826  1.00 28.19  ? 163 TYR B C   1 
ATOM   4944  O O   . TYR B 1 163 ? 143.141 150.636 80.893  1.00 28.19  ? 163 TYR B O   1 
ATOM   4945  C CB  . TYR B 1 163 ? 140.739 152.042 81.423  1.00 28.19  ? 163 TYR B CB  1 
ATOM   4946  C CG  . TYR B 1 163 ? 140.814 152.228 82.926  1.00 28.19  ? 163 TYR B CG  1 
ATOM   4947  C CD1 . TYR B 1 163 ? 141.775 151.572 83.685  1.00 28.19  ? 163 TYR B CD1 1 
ATOM   4948  C CD2 . TYR B 1 163 ? 139.917 153.054 83.587  1.00 28.19  ? 163 TYR B CD2 1 
ATOM   4949  C CE1 . TYR B 1 163 ? 141.844 151.739 85.053  1.00 28.19  ? 163 TYR B CE1 1 
ATOM   4950  C CE2 . TYR B 1 163 ? 139.977 153.225 84.955  1.00 28.19  ? 163 TYR B CE2 1 
ATOM   4951  C CZ  . TYR B 1 163 ? 140.942 152.566 85.683  1.00 28.19  ? 163 TYR B CZ  1 
ATOM   4952  O OH  . TYR B 1 163 ? 141.007 152.734 87.047  1.00 28.19  ? 163 TYR B OH  1 
ATOM   4953  N N   . PRO B 1 164 ? 144.324 152.545 80.909  1.00 28.53  ? 164 PRO B N   1 
ATOM   4954  C CA  . PRO B 1 164 ? 145.592 151.821 81.020  1.00 28.53  ? 164 PRO B CA  1 
ATOM   4955  C C   . PRO B 1 164 ? 145.778 151.216 82.403  1.00 28.53  ? 164 PRO B C   1 
ATOM   4956  O O   . PRO B 1 164 ? 145.104 151.574 83.371  1.00 28.53  ? 164 PRO B O   1 
ATOM   4957  C CB  . PRO B 1 164 ? 146.651 152.897 80.742  1.00 28.53  ? 164 PRO B CB  1 
ATOM   4958  C CG  . PRO B 1 164 ? 145.891 154.139 80.349  1.00 28.53  ? 164 PRO B CG  1 
ATOM   4959  C CD  . PRO B 1 164 ? 144.520 154.001 80.909  1.00 28.53  ? 164 PRO B CD  1 
ATOM   4960  N N   . LEU B 1 165 ? 146.717 150.276 82.480  1.00 26.22  ? 165 LEU B N   1 
ATOM   4961  C CA  . LEU B 1 165 ? 147.062 149.665 83.755  1.00 26.22  ? 165 LEU B CA  1 
ATOM   4962  C C   . LEU B 1 165 ? 147.784 150.677 84.636  1.00 26.22  ? 165 LEU B C   1 
ATOM   4963  O O   . LEU B 1 165 ? 148.721 151.347 84.191  1.00 26.22  ? 165 LEU B O   1 
ATOM   4964  C CB  . LEU B 1 165 ? 147.937 148.433 83.532  1.00 26.22  ? 165 LEU B CB  1 
ATOM   4965  C CG  . LEU B 1 165 ? 148.508 147.748 84.775  1.00 26.22  ? 165 LEU B CG  1 
ATOM   4966  C CD1 . LEU B 1 165 ? 147.489 146.807 85.392  1.00 26.22  ? 165 LEU B CD1 1 
ATOM   4967  C CD2 . LEU B 1 165 ? 149.786 147.005 84.433  1.00 26.22  ? 165 LEU B CD2 1 
ATOM   4968  N N   . LEU B 1 166 ? 147.349 150.786 85.887  1.00 24.82  ? 166 LEU B N   1 
ATOM   4969  C CA  . LEU B 1 166 ? 147.894 151.755 86.827  1.00 24.82  ? 166 LEU B CA  1 
ATOM   4970  C C   . LEU B 1 166 ? 148.842 151.056 87.791  1.00 24.82  ? 166 LEU B C   1 
ATOM   4971  O O   . LEU B 1 166 ? 148.485 150.039 88.393  1.00 24.82  ? 166 LEU B O   1 
ATOM   4972  C CB  . LEU B 1 166 ? 146.776 152.455 87.600  1.00 24.82  ? 166 LEU B CB  1 
ATOM   4973  C CG  . LEU B 1 166 ? 145.722 153.185 86.767  1.00 24.82  ? 166 LEU B CG  1 
ATOM   4974  C CD1 . LEU B 1 166 ? 144.462 153.407 87.583  1.00 24.82  ? 166 LEU B CD1 1 
ATOM   4975  C CD2 . LEU B 1 166 ? 146.262 154.504 86.245  1.00 24.82  ? 166 LEU B CD2 1 
ATOM   4976  N N   . ASN B 1 167 ? 150.046 151.608 87.936  1.00 27.57  ? 167 ASN B N   1 
ATOM   4977  C CA  . ASN B 1 167 ? 151.077 151.039 88.806  1.00 27.57  ? 167 ASN B CA  1 
ATOM   4978  C C   . ASN B 1 167 ? 151.822 152.202 89.454  1.00 27.57  ? 167 ASN B C   1 
ATOM   4979  O O   . ASN B 1 167 ? 152.661 152.841 88.813  1.00 27.57  ? 167 ASN B O   1 
ATOM   4980  C CB  . ASN B 1 167 ? 152.022 150.138 88.020  1.00 27.57  ? 167 ASN B CB  1 
ATOM   4981  C CG  . ASN B 1 167 ? 153.062 149.477 88.898  1.00 27.57  ? 167 ASN B CG  1 
ATOM   4982  O OD1 . ASN B 1 167 ? 152.781 149.097 90.034  1.00 27.57  ? 167 ASN B OD1 1 
ATOM   4983  N ND2 . ASN B 1 167 ? 154.276 149.343 88.378  1.00 27.57  ? 167 ASN B ND2 1 
ATOM   4984  N N   . VAL B 1 168 ? 151.517 152.473 90.724  1.00 26.09  ? 168 VAL B N   1 
ATOM   4985  C CA  . VAL B 1 168 ? 152.109 153.587 91.452  1.00 26.09  ? 168 VAL B CA  1 
ATOM   4986  C C   . VAL B 1 168 ? 152.689 153.075 92.763  1.00 26.09  ? 168 VAL B C   1 
ATOM   4987  O O   . VAL B 1 168 ? 152.318 152.011 93.264  1.00 26.09  ? 168 VAL B O   1 
ATOM   4988  C CB  . VAL B 1 168 ? 151.095 154.720 91.722  1.00 26.09  ? 168 VAL B CB  1 
ATOM   4989  C CG1 . VAL B 1 168 ? 150.449 155.180 90.428  1.00 26.09  ? 168 VAL B CG1 1 
ATOM   4990  C CG2 . VAL B 1 168 ? 150.042 154.265 92.714  1.00 26.09  ? 168 VAL B CG2 1 
ATOM   4991  N N   . THR B 1 169 ? 153.616 153.854 93.315  1.00 27.87  ? 169 THR B N   1 
ATOM   4992  C CA  . THR B 1 169 ? 154.289 153.503 94.557  1.00 27.87  ? 169 THR B CA  1 
ATOM   4993  C C   . THR B 1 169 ? 154.374 154.729 95.455  1.00 27.87  ? 169 THR B C   1 
ATOM   4994  O O   . THR B 1 169 ? 154.351 155.868 94.982  1.00 27.87  ? 169 THR B O   1 
ATOM   4995  C CB  . THR B 1 169 ? 155.695 152.939 94.300  1.00 27.87  ? 169 THR B CB  1 
ATOM   4996  O OG1 . THR B 1 169 ? 156.297 152.560 95.543  1.00 27.87  ? 169 THR B OG1 1 
ATOM   4997  C CG2 . THR B 1 169 ? 156.571 153.970 93.611  1.00 27.87  ? 169 THR B CG2 1 
ATOM   4998  N N   . MET B 1 170 ? 154.463 154.482 96.761  1.00 28.08  ? 170 MET B N   1 
ATOM   4999  C CA  . MET B 1 170 ? 154.567 155.550 97.748  1.00 28.08  ? 170 MET B CA  1 
ATOM   5000  C C   . MET B 1 170 ? 155.305 155.053 98.985  1.00 28.08  ? 170 MET B C   1 
ATOM   5001  O O   . MET B 1 170 ? 154.755 154.259 99.760  1.00 28.08  ? 170 MET B O   1 
ATOM   5002  C CB  . MET B 1 170 ? 153.179 156.072 98.125  1.00 28.08  ? 170 MET B CB  1 
ATOM   5003  C CG  . MET B 1 170 ? 153.195 157.370 98.917  1.00 28.08  ? 170 MET B CG  1 
ATOM   5004  S SD  . MET B 1 170 ? 153.818 158.774 97.973  1.00 28.08  ? 170 MET B SD  1 
ATOM   5005  C CE  . MET B 1 170 ? 152.391 159.172 96.969  1.00 28.08  ? 170 MET B CE  1 
ATOM   5006  N N   . PRO B 1 171 ? 156.539 155.496 99.209  1.00 27.80  ? 171 PRO B N   1 
ATOM   5007  C CA  . PRO B 1 171 ? 157.309 155.022 100.362 1.00 27.80  ? 171 PRO B CA  1 
ATOM   5008  C C   . PRO B 1 171 ? 157.013 155.804 101.632 1.00 27.80  ? 171 PRO B C   1 
ATOM   5009  O O   . PRO B 1 171 ? 156.624 156.973 101.609 1.00 27.80  ? 171 PRO B O   1 
ATOM   5010  C CB  . PRO B 1 171 ? 158.765 155.235 99.920  1.00 27.80  ? 171 PRO B CB  1 
ATOM   5011  C CG  . PRO B 1 171 ? 158.712 156.174 98.736  1.00 27.80  ? 171 PRO B CG  1 
ATOM   5012  C CD  . PRO B 1 171 ? 157.284 156.483 98.414  1.00 27.80  ? 171 PRO B CD  1 
ATOM   5013  N N   . ASN B 1 172 ? 157.210 155.126 102.761 1.00 27.54  ? 172 ASN B N   1 
ATOM   5014  C CA  . ASN B 1 172 ? 157.014 155.714 104.084 1.00 27.54  ? 172 ASN B CA  1 
ATOM   5015  C C   . ASN B 1 172 ? 158.382 156.120 104.619 1.00 27.54  ? 172 ASN B C   1 
ATOM   5016  O O   . ASN B 1 172 ? 159.160 155.278 105.074 1.00 27.54  ? 172 ASN B O   1 
ATOM   5017  C CB  . ASN B 1 172 ? 156.314 154.730 105.017 1.00 27.54  ? 172 ASN B CB  1 
ATOM   5018  C CG  . ASN B 1 172 ? 155.912 155.358 106.339 1.00 27.54  ? 172 ASN B CG  1 
ATOM   5019  O OD1 . ASN B 1 172 ? 156.294 156.484 106.651 1.00 27.54  ? 172 ASN B OD1 1 
ATOM   5020  N ND2 . ASN B 1 172 ? 155.135 154.627 107.125 1.00 27.54  ? 172 ASN B ND2 1 
ATOM   5021  N N   . ASN B 1 173 ? 158.674 157.418 104.565 1.00 30.89  ? 173 ASN B N   1 
ATOM   5022  C CA  . ASN B 1 173 ? 159.945 157.955 105.029 1.00 30.89  ? 173 ASN B CA  1 
ATOM   5023  C C   . ASN B 1 173 ? 159.829 158.656 106.376 1.00 30.89  ? 173 ASN B C   1 
ATOM   5024  O O   . ASN B 1 173 ? 160.792 159.291 106.817 1.00 30.89  ? 173 ASN B O   1 
ATOM   5025  C CB  . ASN B 1 173 ? 160.521 158.913 103.986 1.00 30.89  ? 173 ASN B CB  1 
ATOM   5026  C CG  . ASN B 1 173 ? 160.959 158.200 102.723 1.00 30.89  ? 173 ASN B CG  1 
ATOM   5027  O OD1 . ASN B 1 173 ? 161.508 157.100 102.776 1.00 30.89  ? 173 ASN B OD1 1 
ATOM   5028  N ND2 . ASN B 1 173 ? 160.718 158.825 101.577 1.00 30.89  ? 173 ASN B ND2 1 
ATOM   5029  N N   . TYR B 1 174 ? 158.679 158.558 107.035 1.00 30.61  ? 174 TYR B N   1 
ATOM   5030  C CA  . TYR B 1 174 ? 158.479 159.159 108.343 1.00 30.61  ? 174 TYR B CA  1 
ATOM   5031  C C   . TYR B 1 174 ? 158.816 158.142 109.432 1.00 30.61  ? 174 TYR B C   1 
ATOM   5032  O O   . TYR B 1 174 ? 159.373 157.073 109.168 1.00 30.61  ? 174 TYR B O   1 
ATOM   5033  C CB  . TYR B 1 174 ? 157.047 159.672 108.478 1.00 30.61  ? 174 TYR B CB  1 
ATOM   5034  C CG  . TYR B 1 174 ? 156.656 160.699 107.442 1.00 30.61  ? 174 TYR B CG  1 
ATOM   5035  C CD1 . TYR B 1 174 ? 157.469 161.792 107.176 1.00 30.61  ? 174 TYR B CD1 1 
ATOM   5036  C CD2 . TYR B 1 174 ? 155.469 160.579 106.734 1.00 30.61  ? 174 TYR B CD2 1 
ATOM   5037  C CE1 . TYR B 1 174 ? 157.112 162.733 106.232 1.00 30.61  ? 174 TYR B CE1 1 
ATOM   5038  C CE2 . TYR B 1 174 ? 155.104 161.515 105.789 1.00 30.61  ? 174 TYR B CE2 1 
ATOM   5039  C CZ  . TYR B 1 174 ? 155.928 162.589 105.542 1.00 30.61  ? 174 TYR B CZ  1 
ATOM   5040  O OH  . TYR B 1 174 ? 155.566 163.523 104.600 1.00 30.61  ? 174 TYR B OH  1 
ATOM   5041  N N   . ASN B 1 175 ? 158.480 158.471 110.680 1.00 31.29  ? 175 ASN B N   1 
ATOM   5042  C CA  . ASN B 1 175 ? 158.684 157.572 111.809 1.00 31.29  ? 175 ASN B CA  1 
ATOM   5043  C C   . ASN B 1 175 ? 157.376 157.230 112.516 1.00 31.29  ? 175 ASN B C   1 
ATOM   5044  O O   . ASN B 1 175 ? 157.389 156.845 113.689 1.00 31.29  ? 175 ASN B O   1 
ATOM   5045  C CB  . ASN B 1 175 ? 159.701 158.166 112.790 1.00 31.29  ? 175 ASN B CB  1 
ATOM   5046  C CG  . ASN B 1 175 ? 159.230 159.467 113.423 1.00 31.29  ? 175 ASN B CG  1 
ATOM   5047  O OD1 . ASN B 1 175 ? 158.091 159.894 113.240 1.00 31.29  ? 175 ASN B OD1 1 
ATOM   5048  N ND2 . ASN B 1 175 ? 160.118 160.103 114.176 1.00 31.29  ? 175 ASN B ND2 1 
ATOM   5049  N N   . PHE B 1 176 ? 156.248 157.364 111.823 1.00 29.41  ? 176 PHE B N   1 
ATOM   5050  C CA  . PHE B 1 176 ? 154.946 156.999 112.355 1.00 29.41  ? 176 PHE B CA  1 
ATOM   5051  C C   . PHE B 1 176 ? 154.185 156.195 111.310 1.00 29.41  ? 176 PHE B C   1 
ATOM   5052  O O   . PHE B 1 176 ? 154.448 156.291 110.109 1.00 29.41  ? 176 PHE B O   1 
ATOM   5053  C CB  . PHE B 1 176 ? 154.134 158.235 112.774 1.00 29.41  ? 176 PHE B CB  1 
ATOM   5054  C CG  . PHE B 1 176 ? 154.117 159.333 111.747 1.00 29.41  ? 176 PHE B CG  1 
ATOM   5055  C CD1 . PHE B 1 176 ? 153.238 159.288 110.677 1.00 29.41  ? 176 PHE B CD1 1 
ATOM   5056  C CD2 . PHE B 1 176 ? 154.974 160.414 111.857 1.00 29.41  ? 176 PHE B CD2 1 
ATOM   5057  C CE1 . PHE B 1 176 ? 153.221 160.296 109.734 1.00 29.41  ? 176 PHE B CE1 1 
ATOM   5058  C CE2 . PHE B 1 176 ? 154.959 161.425 110.918 1.00 29.41  ? 176 PHE B CE2 1 
ATOM   5059  C CZ  . PHE B 1 176 ? 154.082 161.365 109.855 1.00 29.41  ? 176 PHE B CZ  1 
ATOM   5060  N N   . ASP B 1 177 ? 153.237 155.391 111.786 1.00 28.39  ? 177 ASP B N   1 
ATOM   5061  C CA  . ASP B 1 177 ? 152.443 154.558 110.896 1.00 28.39  ? 177 ASP B CA  1 
ATOM   5062  C C   . ASP B 1 177 ? 151.487 155.405 110.063 1.00 28.39  ? 177 ASP B C   1 
ATOM   5063  O O   . ASP B 1 177 ? 151.003 156.452 110.500 1.00 28.39  ? 177 ASP B O   1 
ATOM   5064  C CB  . ASP B 1 177 ? 151.651 153.525 111.696 1.00 28.39  ? 177 ASP B CB  1 
ATOM   5065  C CG  . ASP B 1 177 ? 152.532 152.455 112.304 1.00 28.39  ? 177 ASP B CG  1 
ATOM   5066  O OD1 . ASP B 1 177 ? 153.769 152.605 112.255 1.00 28.39  ? 177 ASP B OD1 1 
ATOM   5067  O OD2 . ASP B 1 177 ? 151.987 151.464 112.832 1.00 28.39  ? 177 ASP B OD2 1 
ATOM   5068  N N   . LYS B 1 178 ? 151.215 154.934 108.850 1.00 21.86  ? 178 LYS B N   1 
ATOM   5069  C CA  . LYS B 1 178 ? 150.270 155.565 107.942 1.00 21.86  ? 178 LYS B CA  1 
ATOM   5070  C C   . LYS B 1 178 ? 149.045 154.677 107.782 1.00 21.86  ? 178 LYS B C   1 
ATOM   5071  O O   . LYS B 1 178 ? 149.155 153.449 107.799 1.00 21.86  ? 178 LYS B O   1 
ATOM   5072  C CB  . LYS B 1 178 ? 150.899 155.814 106.570 1.00 21.86  ? 178 LYS B CB  1 
ATOM   5073  C CG  . LYS B 1 178 ? 152.021 156.830 106.552 1.00 21.86  ? 178 LYS B CG  1 
ATOM   5074  C CD  . LYS B 1 178 ? 152.607 156.936 105.158 1.00 21.86  ? 178 LYS B CD  1 
ATOM   5075  C CE  . LYS B 1 178 ? 153.512 158.140 105.018 1.00 21.86  ? 178 LYS B CE  1 
ATOM   5076  N NZ  . LYS B 1 178 ? 153.901 158.357 103.600 1.00 21.86  ? 178 LYS B NZ  1 
ATOM   5077  N N   . LEU B 1 179 ? 147.880 155.300 107.633 1.00 19.20  ? 179 LEU B N   1 
ATOM   5078  C CA  . LEU B 1 179 ? 146.636 154.589 107.372 1.00 19.20  ? 179 LEU B CA  1 
ATOM   5079  C C   . LEU B 1 179 ? 146.057 155.072 106.052 1.00 19.20  ? 179 LEU B C   1 
ATOM   5080  O O   . LEU B 1 179 ? 145.872 156.277 105.855 1.00 19.20  ? 179 LEU B O   1 
ATOM   5081  C CB  . LEU B 1 179 ? 145.630 154.795 108.507 1.00 19.20  ? 179 LEU B CB  1 
ATOM   5082  C CG  . LEU B 1 179 ? 144.226 154.227 108.295 1.00 19.20  ? 179 LEU B CG  1 
ATOM   5083  C CD1 . LEU B 1 179 ? 144.240 152.710 108.350 1.00 19.20  ? 179 LEU B CD1 1 
ATOM   5084  C CD2 . LEU B 1 179 ? 143.268 154.788 109.327 1.00 19.20  ? 179 LEU B CD2 1 
ATOM   5085  N N   . TYR B 1 180 ? 145.772 154.134 105.154 1.00 18.24  ? 180 TYR B N   1 
ATOM   5086  C CA  . TYR B 1 180 ? 145.259 154.434 103.825 1.00 18.24  ? 180 TYR B CA  1 
ATOM   5087  C C   . TYR B 1 180 ? 143.865 153.846 103.667 1.00 18.24  ? 180 TYR B C   1 
ATOM   5088  O O   . TYR B 1 180 ? 143.620 152.701 104.053 1.00 18.24  ? 180 TYR B O   1 
ATOM   5089  C CB  . TYR B 1 180 ? 146.181 153.875 102.738 1.00 18.24  ? 180 TYR B CB  1 
ATOM   5090  C CG  . TYR B 1 180 ? 147.403 154.721 102.464 1.00 18.24  ? 180 TYR B CG  1 
ATOM   5091  C CD1 . TYR B 1 180 ? 147.351 155.774 101.564 1.00 18.24  ? 180 TYR B CD1 1 
ATOM   5092  C CD2 . TYR B 1 180 ? 148.608 154.463 103.100 1.00 18.24  ? 180 TYR B CD2 1 
ATOM   5093  C CE1 . TYR B 1 180 ? 148.462 156.548 101.308 1.00 18.24  ? 180 TYR B CE1 1 
ATOM   5094  C CE2 . TYR B 1 180 ? 149.725 155.233 102.850 1.00 18.24  ? 180 TYR B CE2 1 
ATOM   5095  C CZ  . TYR B 1 180 ? 149.645 156.273 101.954 1.00 18.24  ? 180 TYR B CZ  1 
ATOM   5096  O OH  . TYR B 1 180 ? 150.754 157.044 101.698 1.00 18.24  ? 180 TYR B OH  1 
ATOM   5097  N N   . ILE B 1 181 ? 142.956 154.633 103.100 1.00 18.59  ? 181 ILE B N   1 
ATOM   5098  C CA  . ILE B 1 181 ? 141.590 154.203 102.827 1.00 18.59  ? 181 ILE B CA  1 
ATOM   5099  C C   . ILE B 1 181 ? 141.369 154.251 101.322 1.00 18.59  ? 181 ILE B C   1 
ATOM   5100  O O   . ILE B 1 181 ? 141.609 155.284 100.688 1.00 18.59  ? 181 ILE B O   1 
ATOM   5101  C CB  . ILE B 1 181 ? 140.556 155.078 103.560 1.00 18.59  ? 181 ILE B CB  1 
ATOM   5102  C CG1 . ILE B 1 181 ? 140.917 155.212 105.042 1.00 18.59  ? 181 ILE B CG1 1 
ATOM   5103  C CG2 . ILE B 1 181 ? 139.159 154.507 103.394 1.00 18.59  ? 181 ILE B CG2 1 
ATOM   5104  C CD1 . ILE B 1 181 ? 140.533 154.016 105.882 1.00 18.59  ? 181 ILE B CD1 1 
ATOM   5105  N N   . TRP B 1 182 ? 140.915 153.135 100.754 1.00 16.66  ? 182 TRP B N   1 
ATOM   5106  C CA  . TRP B 1 182 ? 140.647 153.035 99.326  1.00 16.66  ? 182 TRP B CA  1 
ATOM   5107  C C   . TRP B 1 182 ? 139.366 152.234 99.130  1.00 16.66  ? 182 TRP B C   1 
ATOM   5108  O O   . TRP B 1 182 ? 138.737 151.787 100.094 1.00 16.66  ? 182 TRP B O   1 
ATOM   5109  C CB  . TRP B 1 182 ? 141.830 152.405 98.581  1.00 16.66  ? 182 TRP B CB  1 
ATOM   5110  C CG  . TRP B 1 182 ? 142.399 151.189 99.249  1.00 16.66  ? 182 TRP B CG  1 
ATOM   5111  C CD1 . TRP B 1 182 ? 143.262 151.162 100.304 1.00 16.66  ? 182 TRP B CD1 1 
ATOM   5112  C CD2 . TRP B 1 182 ? 142.151 149.823 98.900  1.00 16.66  ? 182 TRP B CD2 1 
ATOM   5113  N NE1 . TRP B 1 182 ? 143.562 149.866 100.638 1.00 16.66  ? 182 TRP B NE1 1 
ATOM   5114  C CE2 . TRP B 1 182 ? 142.893 149.024 99.790  1.00 16.66  ? 182 TRP B CE2 1 
ATOM   5115  C CE3 . TRP B 1 182 ? 141.373 149.198 97.922  1.00 16.66  ? 182 TRP B CE3 1 
ATOM   5116  C CZ2 . TRP B 1 182 ? 142.881 147.633 99.730  1.00 16.66  ? 182 TRP B CZ2 1 
ATOM   5117  C CZ3 . TRP B 1 182 ? 141.361 147.820 97.865  1.00 16.66  ? 182 TRP B CZ3 1 
ATOM   5118  C CH2 . TRP B 1 182 ? 142.110 147.051 98.763  1.00 16.66  ? 182 TRP B CH2 1 
ATOM   5119  N N   . GLY B 1 183 ? 138.973 152.050 97.872  1.00 19.87  ? 183 GLY B N   1 
ATOM   5120  C CA  . GLY B 1 183 ? 137.721 151.369 97.601  1.00 19.87  ? 183 GLY B CA  1 
ATOM   5121  C C   . GLY B 1 183 ? 137.687 150.721 96.236  1.00 19.87  ? 183 GLY B C   1 
ATOM   5122  O O   . GLY B 1 183 ? 138.593 150.881 95.415  1.00 19.87  ? 183 GLY B O   1 
ATOM   5123  N N   . VAL B 1 184 ? 136.608 149.972 96.010  1.00 20.77  ? 184 VAL B N   1 
ATOM   5124  C CA  . VAL B 1 184 ? 136.347 149.279 94.753  1.00 20.77  ? 184 VAL B CA  1 
ATOM   5125  C C   . VAL B 1 184 ? 134.900 149.540 94.358  1.00 20.77  ? 184 VAL B C   1 
ATOM   5126  O O   . VAL B 1 184 ? 134.002 149.506 95.206  1.00 20.77  ? 184 VAL B O   1 
ATOM   5127  C CB  . VAL B 1 184 ? 136.613 147.761 94.868  1.00 20.77  ? 184 VAL B CB  1 
ATOM   5128  C CG1 . VAL B 1 184 ? 136.366 147.068 93.538  1.00 20.77  ? 184 VAL B CG1 1 
ATOM   5129  C CG2 . VAL B 1 184 ? 138.030 147.494 95.346  1.00 20.77  ? 184 VAL B CG2 1 
ATOM   5130  N N   . HIS B 1 185 ? 134.672 149.798 93.074  1.00 21.60  ? 185 HIS B N   1 
ATOM   5131  C CA  . HIS B 1 185 ? 133.341 150.085 92.555  1.00 21.60  ? 185 HIS B CA  1 
ATOM   5132  C C   . HIS B 1 185 ? 132.725 148.821 91.970  1.00 21.60  ? 185 HIS B C   1 
ATOM   5133  O O   . HIS B 1 185 ? 133.376 148.103 91.204  1.00 21.60  ? 185 HIS B O   1 
ATOM   5134  C CB  . HIS B 1 185 ? 133.394 151.183 91.492  1.00 21.60  ? 185 HIS B CB  1 
ATOM   5135  C CG  . HIS B 1 185 ? 132.048 151.599 90.987  1.00 21.60  ? 185 HIS B CG  1 
ATOM   5136  N ND1 . HIS B 1 185 ? 131.706 151.549 89.653  1.00 21.60  ? 185 HIS B ND1 1 
ATOM   5137  C CD2 . HIS B 1 185 ? 130.958 152.070 91.637  1.00 21.60  ? 185 HIS B CD2 1 
ATOM   5138  C CE1 . HIS B 1 185 ? 130.464 151.972 89.503  1.00 21.60  ? 185 HIS B CE1 1 
ATOM   5139  N NE2 . HIS B 1 185 ? 129.987 152.294 90.692  1.00 21.60  ? 185 HIS B NE2 1 
ATOM   5140  N N   . HIS B 1 186 ? 131.471 148.556 92.331  1.00 22.31  ? 186 HIS B N   1 
ATOM   5141  C CA  . HIS B 1 186 ? 130.733 147.408 91.818  1.00 22.31  ? 186 HIS B CA  1 
ATOM   5142  C C   . HIS B 1 186 ? 129.640 147.888 90.874  1.00 22.31  ? 186 HIS B C   1 
ATOM   5143  O O   . HIS B 1 186 ? 128.611 148.400 91.341  1.00 22.31  ? 186 HIS B O   1 
ATOM   5144  C CB  . HIS B 1 186 ? 130.121 146.601 92.964  1.00 22.31  ? 186 HIS B CB  1 
ATOM   5145  C CG  . HIS B 1 186 ? 131.117 146.124 93.974  1.00 22.31  ? 186 HIS B CG  1 
ATOM   5146  N ND1 . HIS B 1 186 ? 132.078 145.181 93.685  1.00 22.31  ? 186 HIS B ND1 1 
ATOM   5147  C CD2 . HIS B 1 186 ? 131.292 146.451 95.276  1.00 22.31  ? 186 HIS B CD2 1 
ATOM   5148  C CE1 . HIS B 1 186 ? 132.806 144.952 94.762  1.00 22.31  ? 186 HIS B CE1 1 
ATOM   5149  N NE2 . HIS B 1 186 ? 132.351 145.711 95.741  1.00 22.31  ? 186 HIS B NE2 1 
ATOM   5150  N N   . PRO B 1 187 ? 129.798 147.746 89.561  1.00 23.82  ? 187 PRO B N   1 
ATOM   5151  C CA  . PRO B 1 187 ? 128.740 148.172 88.640  1.00 23.82  ? 187 PRO B CA  1 
ATOM   5152  C C   . PRO B 1 187 ? 127.547 147.229 88.681  1.00 23.82  ? 187 PRO B C   1 
ATOM   5153  O O   . PRO B 1 187 ? 127.625 146.095 89.158  1.00 23.82  ? 187 PRO B O   1 
ATOM   5154  C CB  . PRO B 1 187 ? 129.424 148.144 87.267  1.00 23.82  ? 187 PRO B CB  1 
ATOM   5155  C CG  . PRO B 1 187 ? 130.892 147.996 87.550  1.00 23.82  ? 187 PRO B CG  1 
ATOM   5156  C CD  . PRO B 1 187 ? 130.985 147.263 88.841  1.00 23.82  ? 187 PRO B CD  1 
ATOM   5157  N N   . SER B 1 188 ? 126.421 147.724 88.167  1.00 26.68  ? 188 SER B N   1 
ATOM   5158  C CA  . SER B 1 188 ? 125.179 146.963 88.169  1.00 26.68  ? 188 SER B CA  1 
ATOM   5159  C C   . SER B 1 188 ? 124.951 146.160 86.895  1.00 26.68  ? 188 SER B C   1 
ATOM   5160  O O   . SER B 1 188 ? 124.189 145.188 86.928  1.00 26.68  ? 188 SER B O   1 
ATOM   5161  C CB  . SER B 1 188 ? 123.985 147.900 88.390  1.00 26.68  ? 188 SER B CB  1 
ATOM   5162  O OG  . SER B 1 188 ? 124.068 149.038 87.552  1.00 26.68  ? 188 SER B OG  1 
ATOM   5163  N N   . THR B 1 189 ? 125.582 146.535 85.784  1.00 29.82  ? 189 THR B N   1 
ATOM   5164  C CA  . THR B 1 189 ? 125.430 145.822 84.524  1.00 29.82  ? 189 THR B CA  1 
ATOM   5165  C C   . THR B 1 189 ? 126.787 145.700 83.848  1.00 29.82  ? 189 THR B C   1 
ATOM   5166  O O   . THR B 1 189 ? 127.724 146.442 84.150  1.00 29.82  ? 189 THR B O   1 
ATOM   5167  C CB  . THR B 1 189 ? 124.444 146.523 83.574  1.00 29.82  ? 189 THR B CB  1 
ATOM   5168  O OG1 . THR B 1 189 ? 124.875 147.869 83.339  1.00 29.82  ? 189 THR B OG1 1 
ATOM   5169  C CG2 . THR B 1 189 ? 123.038 146.538 84.156  1.00 29.82  ? 189 THR B CG2 1 
ATOM   5170  N N   . ASN B 1 190 ? 126.884 144.739 82.925  1.00 32.66  ? 190 ASN B N   1 
ATOM   5171  C CA  . ASN B 1 190 ? 128.103 144.588 82.137  1.00 32.66  ? 190 ASN B CA  1 
ATOM   5172  C C   . ASN B 1 190 ? 128.306 145.776 81.204  1.00 32.66  ? 190 ASN B C   1 
ATOM   5173  O O   . ASN B 1 190 ? 129.445 146.189 80.953  1.00 32.66  ? 190 ASN B O   1 
ATOM   5174  C CB  . ASN B 1 190 ? 128.059 143.285 81.339  1.00 32.66  ? 190 ASN B CB  1 
ATOM   5175  C CG  . ASN B 1 190 ? 128.349 142.069 82.193  1.00 32.66  ? 190 ASN B CG  1 
ATOM   5176  O OD1 . ASN B 1 190 ? 127.538 141.149 82.278  1.00 32.66  ? 190 ASN B OD1 1 
ATOM   5177  N ND2 . ASN B 1 190 ? 129.515 142.055 82.827  1.00 32.66  ? 190 ASN B ND2 1 
ATOM   5178  N N   . GLN B 1 191 ? 127.214 146.329 80.673  1.00 34.76  ? 191 GLN B N   1 
ATOM   5179  C CA  . GLN B 1 191 ? 127.326 147.491 79.798  1.00 34.76  ? 191 GLN B CA  1 
ATOM   5180  C C   . GLN B 1 191 ? 127.886 148.690 80.551  1.00 34.76  ? 191 GLN B C   1 
ATOM   5181  O O   . GLN B 1 191 ? 128.720 149.430 80.020  1.00 34.76  ? 191 GLN B O   1 
ATOM   5182  C CB  . GLN B 1 191 ? 125.965 147.820 79.186  1.00 34.76  ? 191 GLN B CB  1 
ATOM   5183  C CG  . GLN B 1 191 ? 126.030 148.764 77.997  1.00 34.76  ? 191 GLN B CG  1 
ATOM   5184  C CD  . GLN B 1 191 ? 125.823 150.212 78.386  1.00 34.76  ? 191 GLN B CD  1 
ATOM   5185  O OE1 . GLN B 1 191 ? 125.075 150.517 79.315  1.00 34.76  ? 191 GLN B OE1 1 
ATOM   5186  N NE2 . GLN B 1 191 ? 126.488 151.116 77.676  1.00 34.76  ? 191 GLN B NE2 1 
ATOM   5187  N N   . GLU B 1 192 ? 127.438 148.899 81.791  1.00 31.68  ? 192 GLU B N   1 
ATOM   5188  C CA  . GLU B 1 192 ? 128.002 149.962 82.618  1.00 31.68  ? 192 GLU B CA  1 
ATOM   5189  C C   . GLU B 1 192 ? 129.469 149.695 82.932  1.00 31.68  ? 192 GLU B C   1 
ATOM   5190  O O   . GLU B 1 192 ? 130.293 150.618 82.924  1.00 31.68  ? 192 GLU B O   1 
ATOM   5191  C CB  . GLU B 1 192 ? 127.190 150.103 83.904  1.00 31.68  ? 192 GLU B CB  1 
ATOM   5192  C CG  . GLU B 1 192 ? 127.810 151.012 84.944  1.00 31.68  ? 192 GLU B CG  1 
ATOM   5193  C CD  . GLU B 1 192 ? 127.028 151.017 86.239  1.00 31.68  ? 192 GLU B CD  1 
ATOM   5194  O OE1 . GLU B 1 192 ? 125.940 150.409 86.277  1.00 31.68  ? 192 GLU B OE1 1 
ATOM   5195  O OE2 . GLU B 1 192 ? 127.502 151.624 87.220  1.00 31.68  ? 192 GLU B OE2 1 
ATOM   5196  N N   . GLN B 1 193 ? 129.809 148.435 83.218  1.00 28.80  ? 193 GLN B N   1 
ATOM   5197  C CA  . GLN B 1 193 ? 131.203 148.062 83.436  1.00 28.80  ? 193 GLN B CA  1 
ATOM   5198  C C   . GLN B 1 193 ? 132.070 148.443 82.245  1.00 28.80  ? 193 GLN B C   1 
ATOM   5199  O O   . GLN B 1 193 ? 133.160 148.997 82.416  1.00 28.80  ? 193 GLN B O   1 
ATOM   5200  C CB  . GLN B 1 193 ? 131.303 146.561 83.711  1.00 28.80  ? 193 GLN B CB  1 
ATOM   5201  C CG  . GLN B 1 193 ? 132.713 145.987 83.642  1.00 28.80  ? 193 GLN B CG  1 
ATOM   5202  C CD  . GLN B 1 193 ? 133.616 146.464 84.758  1.00 28.80  ? 193 GLN B CD  1 
ATOM   5203  O OE1 . GLN B 1 193 ? 133.206 146.543 85.913  1.00 28.80  ? 193 GLN B OE1 1 
ATOM   5204  N NE2 . GLN B 1 193 ? 134.859 146.778 84.418  1.00 28.80  ? 193 GLN B NE2 1 
ATOM   5205  N N   . THR B 1 194 ? 131.599 148.161 81.030  1.00 31.71  ? 194 THR B N   1 
ATOM   5206  C CA  . THR B 1 194 ? 132.389 148.462 79.840  1.00 31.71  ? 194 THR B CA  1 
ATOM   5207  C C   . THR B 1 194 ? 132.421 149.961 79.556  1.00 31.71  ? 194 THR B C   1 
ATOM   5208  O O   . THR B 1 194 ? 133.442 150.492 79.103  1.00 31.71  ? 194 THR B O   1 
ATOM   5209  C CB  . THR B 1 194 ? 131.838 147.691 78.641  1.00 31.71  ? 194 THR B CB  1 
ATOM   5210  O OG1 . THR B 1 194 ? 131.964 146.284 78.881  1.00 31.71  ? 194 THR B OG1 1 
ATOM   5211  C CG2 . THR B 1 194 ? 132.598 148.043 77.373  1.00 31.71  ? 194 THR B CG2 1 
ATOM   5212  N N   . ASN B 1 195 ? 131.316 150.662 79.819  1.00 33.99  ? 195 ASN B N   1 
ATOM   5213  C CA  . ASN B 1 195 ? 131.260 152.092 79.535  1.00 33.99  ? 195 ASN B CA  1 
ATOM   5214  C C   . ASN B 1 195 ? 132.173 152.879 80.467  1.00 33.99  ? 195 ASN B C   1 
ATOM   5215  O O   . ASN B 1 195 ? 132.909 153.768 80.024  1.00 33.99  ? 195 ASN B O   1 
ATOM   5216  C CB  . ASN B 1 195 ? 129.818 152.589 79.642  1.00 33.99  ? 195 ASN B CB  1 
ATOM   5217  C CG  . ASN B 1 195 ? 129.655 154.014 79.153  1.00 33.99  ? 195 ASN B CG  1 
ATOM   5218  O OD1 . ASN B 1 195 ? 129.215 154.891 79.896  1.00 33.99  ? 195 ASN B OD1 1 
ATOM   5219  N ND2 . ASN B 1 195 ? 130.011 154.253 77.896  1.00 33.99  ? 195 ASN B ND2 1 
ATOM   5220  N N   . LEU B 1 196 ? 132.135 152.573 81.766  1.00 30.06  ? 196 LEU B N   1 
ATOM   5221  C CA  . LEU B 1 196 ? 132.990 153.290 82.707  1.00 30.06  ? 196 LEU B CA  1 
ATOM   5222  C C   . LEU B 1 196 ? 134.448 152.871 82.566  1.00 30.06  ? 196 LEU B C   1 
ATOM   5223  O O   . LEU B 1 196 ? 135.346 153.720 82.550  1.00 30.06  ? 196 LEU B O   1 
ATOM   5224  C CB  . LEU B 1 196 ? 132.503 153.064 84.138  1.00 30.06  ? 196 LEU B CB  1 
ATOM   5225  C CG  . LEU B 1 196 ? 131.224 153.799 84.541  1.00 30.06  ? 196 LEU B CG  1 
ATOM   5226  C CD1 . LEU B 1 196 ? 130.988 153.682 86.034  1.00 30.06  ? 196 LEU B CD1 1 
ATOM   5227  C CD2 . LEU B 1 196 ? 131.296 155.256 84.124  1.00 30.06  ? 196 LEU B CD2 1 
ATOM   5228  N N   . TYR B 1 197 ? 134.702 151.570 82.460  1.00 28.28  ? 197 TYR B N   1 
ATOM   5229  C CA  . TYR B 1 197 ? 136.050 151.027 82.379  1.00 28.28  ? 197 TYR B CA  1 
ATOM   5230  C C   . TYR B 1 197 ? 136.142 150.166 81.128  1.00 28.28  ? 197 TYR B C   1 
ATOM   5231  O O   . TYR B 1 197 ? 135.261 149.340 80.878  1.00 28.28  ? 197 TYR B O   1 
ATOM   5232  C CB  . TYR B 1 197 ? 136.375 150.207 83.628  1.00 28.28  ? 197 TYR B CB  1 
ATOM   5233  C CG  . TYR B 1 197 ? 135.913 150.873 84.904  1.00 28.28  ? 197 TYR B CG  1 
ATOM   5234  C CD1 . TYR B 1 197 ? 136.596 151.957 85.435  1.00 28.28  ? 197 TYR B CD1 1 
ATOM   5235  C CD2 . TYR B 1 197 ? 134.778 150.427 85.566  1.00 28.28  ? 197 TYR B CD2 1 
ATOM   5236  C CE1 . TYR B 1 197 ? 136.165 152.571 86.595  1.00 28.28  ? 197 TYR B CE1 1 
ATOM   5237  C CE2 . TYR B 1 197 ? 134.341 151.033 86.725  1.00 28.28  ? 197 TYR B CE2 1 
ATOM   5238  C CZ  . TYR B 1 197 ? 135.038 152.104 87.235  1.00 28.28  ? 197 TYR B CZ  1 
ATOM   5239  O OH  . TYR B 1 197 ? 134.603 152.707 88.390  1.00 28.28  ? 197 TYR B OH  1 
ATOM   5240  N N   . VAL B 1 198 ? 137.203 150.355 80.345  1.00 29.93  ? 198 VAL B N   1 
ATOM   5241  C CA  . VAL B 1 198 ? 137.282 149.691 79.046  1.00 29.93  ? 198 VAL B CA  1 
ATOM   5242  C C   . VAL B 1 198 ? 137.296 148.175 79.212  1.00 29.93  ? 198 VAL B C   1 
ATOM   5243  O O   . VAL B 1 198 ? 136.625 147.449 78.469  1.00 29.93  ? 198 VAL B O   1 
ATOM   5244  C CB  . VAL B 1 198 ? 138.508 150.194 78.265  1.00 29.93  ? 198 VAL B CB  1 
ATOM   5245  C CG1 . VAL B 1 198 ? 138.681 149.406 76.979  1.00 29.93  ? 198 VAL B CG1 1 
ATOM   5246  C CG2 . VAL B 1 198 ? 138.354 151.669 77.965  1.00 29.93  ? 198 VAL B CG2 1 
ATOM   5247  N N   . GLN B 1 199 ? 138.047 147.676 80.190  1.00 30.41  ? 199 GLN B N   1 
ATOM   5248  C CA  . GLN B 1 199 ? 138.140 146.239 80.402  1.00 30.41  ? 199 GLN B CA  1 
ATOM   5249  C C   . GLN B 1 199 ? 136.822 145.682 80.930  1.00 30.41  ? 199 GLN B C   1 
ATOM   5250  O O   . GLN B 1 199 ? 136.087 146.348 81.662  1.00 30.41  ? 199 GLN B O   1 
ATOM   5251  C CB  . GLN B 1 199 ? 139.273 145.915 81.375  1.00 30.41  ? 199 GLN B CB  1 
ATOM   5252  C CG  . GLN B 1 199 ? 140.663 146.022 80.768  1.00 30.41  ? 199 GLN B CG  1 
ATOM   5253  C CD  . GLN B 1 199 ? 141.098 147.459 80.555  1.00 30.41  ? 199 GLN B CD  1 
ATOM   5254  O OE1 . GLN B 1 199 ? 141.310 148.203 81.511  1.00 30.41  ? 199 GLN B OE1 1 
ATOM   5255  N NE2 . GLN B 1 199 ? 141.228 147.856 79.297  1.00 30.41  ? 199 GLN B NE2 1 
ATOM   5256  N N   . ALA B 1 200 ? 136.530 144.439 80.548  1.00 31.04  ? 200 ALA B N   1 
ATOM   5257  C CA  . ALA B 1 200 ? 135.292 143.784 80.947  1.00 31.04  ? 200 ALA B CA  1 
ATOM   5258  C C   . ALA B 1 200 ? 135.349 143.204 82.353  1.00 31.04  ? 200 ALA B C   1 
ATOM   5259  O O   . ALA B 1 200 ? 134.321 142.737 82.854  1.00 31.04  ? 200 ALA B O   1 
ATOM   5260  C CB  . ALA B 1 200 ? 134.939 142.676 79.953  1.00 31.04  ? 200 ALA B CB  1 
ATOM   5261  N N   . SER B 1 201 ? 136.513 143.221 82.997  1.00 30.31  ? 201 SER B N   1 
ATOM   5262  C CA  . SER B 1 201 ? 136.652 142.706 84.355  1.00 30.31  ? 201 SER B CA  1 
ATOM   5263  C C   . SER B 1 201 ? 137.784 143.457 85.035  1.00 30.31  ? 201 SER B C   1 
ATOM   5264  O O   . SER B 1 201 ? 138.934 143.374 84.595  1.00 30.31  ? 201 SER B O   1 
ATOM   5265  C CB  . SER B 1 201 ? 136.925 141.201 84.348  1.00 30.31  ? 201 SER B CB  1 
ATOM   5266  O OG  . SER B 1 201 ? 136.852 140.663 85.656  1.00 30.31  ? 201 SER B OG  1 
ATOM   5267  N N   . GLY B 1 202 ? 137.458 144.190 86.101  1.00 26.81  ? 202 GLY B N   1 
ATOM   5268  C CA  . GLY B 1 202 ? 138.441 144.971 86.818  1.00 26.81  ? 202 GLY B CA  1 
ATOM   5269  C C   . GLY B 1 202 ? 139.187 144.159 87.861  1.00 26.81  ? 202 GLY B C   1 
ATOM   5270  O O   . GLY B 1 202 ? 138.910 142.986 88.103  1.00 26.81  ? 202 GLY B O   1 
ATOM   5271  N N   . ARG B 1 203 ? 140.155 144.818 88.492  1.00 24.99  ? 203 ARG B N   1 
ATOM   5272  C CA  . ARG B 1 203 ? 141.002 144.190 89.496  1.00 24.99  ? 203 ARG B CA  1 
ATOM   5273  C C   . ARG B 1 203 ? 141.764 145.276 90.237  1.00 24.99  ? 203 ARG B C   1 
ATOM   5274  O O   . ARG B 1 203 ? 142.285 146.203 89.613  1.00 24.99  ? 203 ARG B O   1 
ATOM   5275  C CB  . ARG B 1 203 ? 141.975 143.195 88.850  1.00 24.99  ? 203 ARG B CB  1 
ATOM   5276  C CG  . ARG B 1 203 ? 142.913 142.513 89.820  1.00 24.99  ? 203 ARG B CG  1 
ATOM   5277  C CD  . ARG B 1 203 ? 144.037 141.810 89.081  1.00 24.99  ? 203 ARG B CD  1 
ATOM   5278  N NE  . ARG B 1 203 ? 144.726 142.690 88.144  1.00 24.99  ? 203 ARG B NE  1 
ATOM   5279  C CZ  . ARG B 1 203 ? 145.604 143.620 88.493  1.00 24.99  ? 203 ARG B CZ  1 
ATOM   5280  N NH1 . ARG B 1 203 ? 145.919 143.834 89.760  1.00 24.99  ? 203 ARG B NH1 1 
ATOM   5281  N NH2 . ARG B 1 203 ? 146.185 144.351 87.546  1.00 24.99  ? 203 ARG B NH2 1 
ATOM   5282  N N   . VAL B 1 204 ? 141.820 145.161 91.562  1.00 23.02  ? 204 VAL B N   1 
ATOM   5283  C CA  . VAL B 1 204 ? 142.503 146.130 92.413  1.00 23.02  ? 204 VAL B CA  1 
ATOM   5284  C C   . VAL B 1 204 ? 143.436 145.372 93.345  1.00 23.02  ? 204 VAL B C   1 
ATOM   5285  O O   . VAL B 1 204 ? 142.989 144.504 94.102  1.00 23.02  ? 204 VAL B O   1 
ATOM   5286  C CB  . VAL B 1 204 ? 141.514 146.987 93.223  1.00 23.02  ? 204 VAL B CB  1 
ATOM   5287  C CG1 . VAL B 1 204 ? 142.266 147.903 94.172  1.00 23.02  ? 204 VAL B CG1 1 
ATOM   5288  C CG2 . VAL B 1 204 ? 140.625 147.796 92.296  1.00 23.02  ? 204 VAL B CG2 1 
ATOM   5289  N N   . THR B 1 205 ? 144.725 145.702 93.295  1.00 23.25  ? 205 THR B N   1 
ATOM   5290  C CA  . THR B 1 205 ? 145.737 145.089 94.149  1.00 23.25  ? 205 THR B CA  1 
ATOM   5291  C C   . THR B 1 205 ? 146.459 146.182 94.923  1.00 23.25  ? 205 THR B C   1 
ATOM   5292  O O   . THR B 1 205 ? 147.056 147.080 94.321  1.00 23.25  ? 205 THR B O   1 
ATOM   5293  C CB  . THR B 1 205 ? 146.735 144.272 93.324  1.00 23.25  ? 205 THR B CB  1 
ATOM   5294  O OG1 . THR B 1 205 ? 146.028 143.407 92.427  1.00 23.25  ? 205 THR B OG1 1 
ATOM   5295  C CG2 . THR B 1 205 ? 147.623 143.435 94.233  1.00 23.25  ? 205 THR B CG2 1 
ATOM   5296  N N   . VAL B 1 206 ? 146.404 146.104 96.250  1.00 21.60  ? 206 VAL B N   1 
ATOM   5297  C CA  . VAL B 1 206 ? 147.119 147.018 97.134  1.00 21.60  ? 206 VAL B CA  1 
ATOM   5298  C C   . VAL B 1 206 ? 147.922 146.181 98.118  1.00 21.60  ? 206 VAL B C   1 
ATOM   5299  O O   . VAL B 1 206 ? 147.363 145.317 98.801  1.00 21.60  ? 206 VAL B O   1 
ATOM   5300  C CB  . VAL B 1 206 ? 146.161 147.965 97.882  1.00 21.60  ? 206 VAL B CB  1 
ATOM   5301  C CG1 . VAL B 1 206 ? 146.936 148.870 98.822  1.00 21.60  ? 206 VAL B CG1 1 
ATOM   5302  C CG2 . VAL B 1 206 ? 145.351 148.790 96.898  1.00 21.60  ? 206 VAL B CG2 1 
ATOM   5303  N N   . SER B 1 207 ? 149.226 146.438 98.198  1.00 23.99  ? 207 SER B N   1 
ATOM   5304  C CA  . SER B 1 207 ? 150.102 145.579 98.979  1.00 23.99  ? 207 SER B CA  1 
ATOM   5305  C C   . SER B 1 207 ? 151.270 146.376 99.539  1.00 23.99  ? 207 SER B C   1 
ATOM   5306  O O   . SER B 1 207 ? 151.631 147.438 99.027  1.00 23.99  ? 207 SER B O   1 
ATOM   5307  C CB  . SER B 1 207 ? 150.626 144.411 98.138  1.00 23.99  ? 207 SER B CB  1 
ATOM   5308  O OG  . SER B 1 207 ? 151.222 144.879 96.942  1.00 23.99  ? 207 SER B OG  1 
ATOM   5309  N N   . THR B 1 208 ? 151.852 145.841 100.605 1.00 26.70  ? 208 THR B N   1 
ATOM   5310  C CA  . THR B 1 208 ? 153.108 146.299 101.182 1.00 26.70  ? 208 THR B CA  1 
ATOM   5311  C C   . THR B 1 208 ? 154.112 145.147 101.125 1.00 26.70  ? 208 THR B C   1 
ATOM   5312  O O   . THR B 1 208 ? 153.862 144.109 100.508 1.00 26.70  ? 208 THR B O   1 
ATOM   5313  C CB  . THR B 1 208 ? 152.908 146.804 102.614 1.00 26.70  ? 208 THR B CB  1 
ATOM   5314  O OG1 . THR B 1 208 ? 152.301 145.777 103.407 1.00 26.70  ? 208 THR B OG1 1 
ATOM   5315  C CG2 . THR B 1 208 ? 152.024 148.039 102.630 1.00 26.70  ? 208 THR B CG2 1 
ATOM   5316  N N   . ARG B 1 209 ? 155.263 145.337 101.771 1.00 28.94  ? 209 ARG B N   1 
ATOM   5317  C CA  . ARG B 1 209 ? 156.263 144.277 101.817 1.00 28.94  ? 209 ARG B CA  1 
ATOM   5318  C C   . ARG B 1 209 ? 155.854 143.114 102.711 1.00 28.94  ? 209 ARG B C   1 
ATOM   5319  O O   . ARG B 1 209 ? 156.531 142.081 102.695 1.00 28.94  ? 209 ARG B O   1 
ATOM   5320  C CB  . ARG B 1 209 ? 157.606 144.833 102.289 1.00 28.94  ? 209 ARG B CB  1 
ATOM   5321  C CG  . ARG B 1 209 ? 158.248 145.820 101.332 1.00 28.94  ? 209 ARG B CG  1 
ATOM   5322  C CD  . ARG B 1 209 ? 159.760 145.710 101.370 1.00 28.94  ? 209 ARG B CD  1 
ATOM   5323  N NE  . ARG B 1 209 ? 160.408 146.887 100.806 1.00 28.94  ? 209 ARG B NE  1 
ATOM   5324  C CZ  . ARG B 1 209 ? 160.811 147.932 101.516 1.00 28.94  ? 209 ARG B CZ  1 
ATOM   5325  N NH1 . ARG B 1 209 ? 160.651 147.978 102.828 1.00 28.94  ? 209 ARG B NH1 1 
ATOM   5326  N NH2 . ARG B 1 209 ? 161.390 148.955 100.894 1.00 28.94  ? 209 ARG B NH2 1 
ATOM   5327  N N   . ARG B 1 210 ? 154.775 143.250 103.484 1.00 30.90  ? 210 ARG B N   1 
ATOM   5328  C CA  . ARG B 1 210 ? 154.360 142.207 104.409 1.00 30.90  ? 210 ARG B CA  1 
ATOM   5329  C C   . ARG B 1 210 ? 152.889 141.827 104.301 1.00 30.90  ? 210 ARG B C   1 
ATOM   5330  O O   . ARG B 1 210 ? 152.432 140.983 105.079 1.00 30.90  ? 210 ARG B O   1 
ATOM   5331  C CB  . ARG B 1 210 ? 154.660 142.630 105.854 1.00 30.90  ? 210 ARG B CB  1 
ATOM   5332  C CG  . ARG B 1 210 ? 153.881 143.847 106.313 1.00 30.90  ? 210 ARG B CG  1 
ATOM   5333  C CD  . ARG B 1 210 ? 154.166 144.171 107.772 1.00 30.90  ? 210 ARG B CD  1 
ATOM   5334  N NE  . ARG B 1 210 ? 153.132 145.012 108.367 1.00 30.90  ? 210 ARG B NE  1 
ATOM   5335  C CZ  . ARG B 1 210 ? 152.921 146.285 108.059 1.00 30.90  ? 210 ARG B CZ  1 
ATOM   5336  N NH1 . ARG B 1 210 ? 153.671 146.917 107.170 1.00 30.90  ? 210 ARG B NH1 1 
ATOM   5337  N NH2 . ARG B 1 210 ? 151.937 146.943 108.664 1.00 30.90  ? 210 ARG B NH2 1 
ATOM   5338  N N   . SER B 1 211 ? 152.137 142.409 103.369 1.00 27.54  ? 211 SER B N   1 
ATOM   5339  C CA  . SER B 1 211 ? 150.714 142.126 103.255 1.00 27.54  ? 211 SER B CA  1 
ATOM   5340  C C   . SER B 1 211 ? 150.264 142.385 101.824 1.00 27.54  ? 211 SER B C   1 
ATOM   5341  O O   . SER B 1 211 ? 150.964 143.024 101.036 1.00 27.54  ? 211 SER B O   1 
ATOM   5342  C CB  . SER B 1 211 ? 149.897 142.967 104.242 1.00 27.54  ? 211 SER B CB  1 
ATOM   5343  O OG  . SER B 1 211 ? 149.569 144.228 103.687 1.00 27.54  ? 211 SER B OG  1 
ATOM   5344  N N   . GLN B 1 212 ? 149.080 141.873 101.494 1.00 25.86  ? 212 GLN B N   1 
ATOM   5345  C CA  . GLN B 1 212 ? 148.509 142.053 100.167 1.00 25.86  ? 212 GLN B CA  1 
ATOM   5346  C C   . GLN B 1 212 ? 146.998 141.894 100.244 1.00 25.86  ? 212 GLN B C   1 
ATOM   5347  O O   . GLN B 1 212 ? 146.481 141.139 101.071 1.00 25.86  ? 212 GLN B O   1 
ATOM   5348  C CB  . GLN B 1 212 ? 149.095 141.057 99.161  1.00 25.86  ? 212 GLN B CB  1 
ATOM   5349  C CG  . GLN B 1 212 ? 148.776 139.605 99.473  1.00 25.86  ? 212 GLN B CG  1 
ATOM   5350  C CD  . GLN B 1 212 ? 149.255 138.656 98.395  1.00 25.86  ? 212 GLN B CD  1 
ATOM   5351  O OE1 . GLN B 1 212 ? 149.717 139.081 97.339  1.00 25.86  ? 212 GLN B OE1 1 
ATOM   5352  N NE2 . GLN B 1 212 ? 149.147 137.360 98.659  1.00 25.86  ? 212 GLN B NE2 1 
ATOM   5353  N N   . GLN B 1 213 ? 146.299 142.619 99.371  1.00 23.16  ? 213 GLN B N   1 
ATOM   5354  C CA  . GLN B 1 213 ? 144.852 142.502 99.230  1.00 23.16  ? 213 GLN B CA  1 
ATOM   5355  C C   . GLN B 1 213 ? 144.490 142.698 97.767  1.00 23.16  ? 213 GLN B C   1 
ATOM   5356  O O   . GLN B 1 213 ? 144.906 143.685 97.155  1.00 23.16  ? 213 GLN B O   1 
ATOM   5357  C CB  . GLN B 1 213 ? 144.111 143.532 100.092 1.00 23.16  ? 213 GLN B CB  1 
ATOM   5358  C CG  . GLN B 1 213 ? 144.228 143.320 101.590 1.00 23.16  ? 213 GLN B CG  1 
ATOM   5359  C CD  . GLN B 1 213 ? 143.717 144.503 102.386 1.00 23.16  ? 213 GLN B CD  1 
ATOM   5360  O OE1 . GLN B 1 213 ? 144.470 145.421 102.705 1.00 23.16  ? 213 GLN B OE1 1 
ATOM   5361  N NE2 . GLN B 1 213 ? 142.433 144.485 102.714 1.00 23.16  ? 213 GLN B NE2 1 
ATOM   5362  N N   . THR B 1 214 ? 143.722 141.764 97.212  1.00 24.05  ? 214 THR B N   1 
ATOM   5363  C CA  . THR B 1 214 ? 143.225 141.871 95.846  1.00 24.05  ? 214 THR B CA  1 
ATOM   5364  C C   . THR B 1 214 ? 141.719 141.666 95.849  1.00 24.05  ? 214 THR B C   1 
ATOM   5365  O O   . THR B 1 214 ? 141.223 140.698 96.432  1.00 24.05  ? 214 THR B O   1 
ATOM   5366  C CB  . THR B 1 214 ? 143.896 140.854 94.917  1.00 24.05  ? 214 THR B CB  1 
ATOM   5367  O OG1 . THR B 1 214 ? 145.312 141.074 94.907  1.00 24.05  ? 214 THR B OG1 1 
ATOM   5368  C CG2 . THR B 1 214 ? 143.364 140.996 93.499  1.00 24.05  ? 214 THR B CG2 1 
ATOM   5369  N N   . ILE B 1 215 ? 140.998 142.576 95.198  1.00 21.87  ? 215 ILE B N   1 
ATOM   5370  C CA  . ILE B 1 215 ? 139.541 142.556 95.151  1.00 21.87  ? 215 ILE B CA  1 
ATOM   5371  C C   . ILE B 1 215 ? 139.103 142.519 93.695  1.00 21.87  ? 215 ILE B C   1 
ATOM   5372  O O   . ILE B 1 215 ? 139.568 143.325 92.881  1.00 21.87  ? 215 ILE B O   1 
ATOM   5373  C CB  . ILE B 1 215 ? 138.930 143.775 95.867  1.00 21.87  ? 215 ILE B CB  1 
ATOM   5374  C CG1 . ILE B 1 215 ? 139.702 144.096 97.149  1.00 21.87  ? 215 ILE B CG1 1 
ATOM   5375  C CG2 . ILE B 1 215 ? 137.460 143.536 96.165  1.00 21.87  ? 215 ILE B CG2 1 
ATOM   5376  C CD1 . ILE B 1 215 ? 139.536 143.065 98.239  1.00 21.87  ? 215 ILE B CD1 1 
ATOM   5377  N N   . VAL B 1 216 ? 138.215 141.589 93.371  1.00 23.44  ? 216 VAL B N   1 
ATOM   5378  C CA  . VAL B 1 216 ? 137.601 141.499 92.049  1.00 23.44  ? 216 VAL B CA  1 
ATOM   5379  C C   . VAL B 1 216 ? 136.179 142.038 92.158  1.00 23.44  ? 216 VAL B C   1 
ATOM   5380  O O   . VAL B 1 216 ? 135.406 141.540 92.990  1.00 23.44  ? 216 VAL B O   1 
ATOM   5381  C CB  . VAL B 1 216 ? 137.606 140.059 91.516  1.00 23.44  ? 216 VAL B CB  1 
ATOM   5382  C CG1 . VAL B 1 216 ? 137.062 140.020 90.098  1.00 23.44  ? 216 VAL B CG1 1 
ATOM   5383  C CG2 . VAL B 1 216 ? 139.008 139.481 91.567  1.00 23.44  ? 216 VAL B CG2 1 
ATOM   5384  N N   . PRO B 1 217 ? 135.801 143.041 91.370  1.00 23.44  ? 217 PRO B N   1 
ATOM   5385  C CA  . PRO B 1 217 ? 134.470 143.639 91.522  1.00 23.44  ? 217 PRO B CA  1 
ATOM   5386  C C   . PRO B 1 217 ? 133.351 142.675 91.160  1.00 23.44  ? 217 PRO B C   1 
ATOM   5387  O O   . PRO B 1 217 ? 133.505 141.782 90.324  1.00 23.44  ? 217 PRO B O   1 
ATOM   5388  C CB  . PRO B 1 217 ? 134.503 144.829 90.557  1.00 23.44  ? 217 PRO B CB  1 
ATOM   5389  C CG  . PRO B 1 217 ? 135.580 144.501 89.582  1.00 23.44  ? 217 PRO B CG  1 
ATOM   5390  C CD  . PRO B 1 217 ? 136.602 143.723 90.342  1.00 23.44  ? 217 PRO B CD  1 
ATOM   5391  N N   . ASN B 1 218 ? 132.209 142.874 91.810  1.00 26.07  ? 218 ASN B N   1 
ATOM   5392  C CA  . ASN B 1 218 ? 130.998 142.109 91.562  1.00 26.07  ? 218 ASN B CA  1 
ATOM   5393  C C   . ASN B 1 218 ? 130.040 142.924 90.702  1.00 26.07  ? 218 ASN B C   1 
ATOM   5394  O O   . ASN B 1 218 ? 129.989 144.153 90.792  1.00 26.07  ? 218 ASN B O   1 
ATOM   5395  C CB  . ASN B 1 218 ? 130.317 141.728 92.877  1.00 26.07  ? 218 ASN B CB  1 
ATOM   5396  C CG  . ASN B 1 218 ? 131.293 141.191 93.905  1.00 26.07  ? 218 ASN B CG  1 
ATOM   5397  O OD1 . ASN B 1 218 ? 132.294 140.566 93.560  1.00 26.07  ? 218 ASN B OD1 1 
ATOM   5398  N ND2 . ASN B 1 218 ? 131.004 141.435 95.178  1.00 26.07  ? 218 ASN B ND2 1 
ATOM   5399  N N   . ILE B 1 219 ? 129.276 142.229 89.864  1.00 25.51  ? 219 ILE B N   1 
ATOM   5400  C CA  . ILE B 1 219 ? 128.343 142.860 88.937  1.00 25.51  ? 219 ILE B CA  1 
ATOM   5401  C C   . ILE B 1 219 ? 126.951 142.302 89.197  1.00 25.51  ? 219 ILE B C   1 
ATOM   5402  O O   . ILE B 1 219 ? 126.779 141.085 89.320  1.00 25.51  ? 219 ILE B O   1 
ATOM   5403  C CB  . ILE B 1 219 ? 128.765 142.639 87.473  1.00 25.51  ? 219 ILE B CB  1 
ATOM   5404  C CG1 . ILE B 1 219 ? 129.885 143.611 87.094  1.00 25.51  ? 219 ILE B CG1 1 
ATOM   5405  C CG2 . ILE B 1 219 ? 127.580 142.803 86.536  1.00 25.51  ? 219 ILE B CG2 1 
ATOM   5406  C CD1 . ILE B 1 219 ? 130.667 143.199 85.870  1.00 25.51  ? 219 ILE B CD1 1 
ATOM   5407  N N   . GLY B 1 220 ? 125.965 143.192 89.292  1.00 24.86  ? 220 GLY B N   1 
ATOM   5408  C CA  . GLY B 1 220 ? 124.591 142.782 89.500  1.00 24.86  ? 220 GLY B CA  1 
ATOM   5409  C C   . GLY B 1 220 ? 123.709 143.894 90.028  1.00 24.86  ? 220 GLY B C   1 
ATOM   5410  O O   . GLY B 1 220 ? 124.192 144.808 90.701  1.00 24.86  ? 220 GLY B O   1 
ATOM   5411  N N   . SER B 1 221 ? 122.415 143.827 89.729  1.00 24.72  ? 221 SER B N   1 
ATOM   5412  C CA  . SER B 1 221 ? 121.487 144.853 90.182  1.00 24.72  ? 221 SER B CA  1 
ATOM   5413  C C   . SER B 1 221 ? 121.268 144.761 91.687  1.00 24.72  ? 221 SER B C   1 
ATOM   5414  O O   . SER B 1 221 ? 121.314 143.683 92.284  1.00 24.72  ? 221 SER B O   1 
ATOM   5415  C CB  . SER B 1 221 ? 120.151 144.727 89.453  1.00 24.72  ? 221 SER B CB  1 
ATOM   5416  O OG  . SER B 1 221 ? 120.270 145.125 88.099  1.00 24.72  ? 221 SER B OG  1 
ATOM   5417  N N   . ARG B 1 222 ? 121.027 145.913 92.296  1.00 23.60  ? 222 ARG B N   1 
ATOM   5418  C CA  . ARG B 1 222 ? 120.846 146.049 93.731  1.00 23.60  ? 222 ARG B CA  1 
ATOM   5419  C C   . ARG B 1 222 ? 119.740 147.062 93.981  1.00 23.60  ? 222 ARG B C   1 
ATOM   5420  O O   . ARG B 1 222 ? 119.406 147.852 93.091  1.00 23.60  ? 222 ARG B O   1 
ATOM   5421  C CB  . ARG B 1 222 ? 122.152 146.483 94.410  1.00 23.60  ? 222 ARG B CB  1 
ATOM   5422  C CG  . ARG B 1 222 ? 123.264 145.454 94.282  1.00 23.60  ? 222 ARG B CG  1 
ATOM   5423  C CD  . ARG B 1 222 ? 124.584 145.972 94.797  1.00 23.60  ? 222 ARG B CD  1 
ATOM   5424  N NE  . ARG B 1 222 ? 125.655 145.001 94.608  1.00 23.60  ? 222 ARG B NE  1 
ATOM   5425  C CZ  . ARG B 1 222 ? 126.398 144.907 93.514  1.00 23.60  ? 222 ARG B CZ  1 
ATOM   5426  N NH1 . ARG B 1 222 ? 126.205 145.706 92.478  1.00 23.60  ? 222 ARG B NH1 1 
ATOM   5427  N NH2 . ARG B 1 222 ? 127.357 143.989 93.458  1.00 23.60  ? 222 ARG B NH2 1 
ATOM   5428  N N   . PRO B 1 223 ? 119.132 147.046 95.168  1.00 25.26  ? 223 PRO B N   1 
ATOM   5429  C CA  . PRO B 1 223 ? 118.062 148.010 95.455  1.00 25.26  ? 223 PRO B CA  1 
ATOM   5430  C C   . PRO B 1 223 ? 118.554 149.445 95.337  1.00 25.26  ? 223 PRO B C   1 
ATOM   5431  O O   . PRO B 1 223 ? 119.688 149.766 95.696  1.00 25.26  ? 223 PRO B O   1 
ATOM   5432  C CB  . PRO B 1 223 ? 117.652 147.671 96.892  1.00 25.26  ? 223 PRO B CB  1 
ATOM   5433  C CG  . PRO B 1 223 ? 118.066 146.263 97.083  1.00 25.26  ? 223 PRO B CG  1 
ATOM   5434  C CD  . PRO B 1 223 ? 119.299 146.071 96.260  1.00 25.26  ? 223 PRO B CD  1 
ATOM   5435  N N   . TRP B 1 224 ? 117.681 150.310 94.825  1.00 26.91  ? 224 TRP B N   1 
ATOM   5436  C CA  . TRP B 1 224 ? 118.041 151.703 94.606  1.00 26.91  ? 224 TRP B CA  1 
ATOM   5437  C C   . TRP B 1 224 ? 118.217 152.429 95.932  1.00 26.91  ? 224 TRP B C   1 
ATOM   5438  O O   . TRP B 1 224 ? 117.354 152.359 96.812  1.00 26.91  ? 224 TRP B O   1 
ATOM   5439  C CB  . TRP B 1 224 ? 116.969 152.400 93.771  1.00 26.91  ? 224 TRP B CB  1 
ATOM   5440  C CG  . TRP B 1 224 ? 117.219 152.363 92.301  1.00 26.91  ? 224 TRP B CG  1 
ATOM   5441  C CD1 . TRP B 1 224 ? 117.796 151.353 91.592  1.00 26.91  ? 224 TRP B CD1 1 
ATOM   5442  C CD2 . TRP B 1 224 ? 116.895 153.385 91.354  1.00 26.91  ? 224 TRP B CD2 1 
ATOM   5443  N NE1 . TRP B 1 224 ? 117.852 151.683 90.260  1.00 26.91  ? 224 TRP B NE1 1 
ATOM   5444  C CE2 . TRP B 1 224 ? 117.305 152.926 90.088  1.00 26.91  ? 224 TRP B CE2 1 
ATOM   5445  C CE3 . TRP B 1 224 ? 116.298 154.645 91.453  1.00 26.91  ? 224 TRP B CE3 1 
ATOM   5446  C CZ2 . TRP B 1 224 ? 117.140 153.683 88.932  1.00 26.91  ? 224 TRP B CZ2 1 
ATOM   5447  C CZ3 . TRP B 1 224 ? 116.133 155.393 90.305  1.00 26.91  ? 224 TRP B CZ3 1 
ATOM   5448  C CH2 . TRP B 1 224 ? 116.551 154.910 89.061  1.00 26.91  ? 224 TRP B CH2 1 
ATOM   5449  N N   . VAL B 1 225 ? 119.338 153.131 96.072  1.00 23.87  ? 225 VAL B N   1 
ATOM   5450  C CA  . VAL B 1 225 ? 119.600 154.002 97.211  1.00 23.87  ? 225 VAL B CA  1 
ATOM   5451  C C   . VAL B 1 225 ? 120.033 155.346 96.645  1.00 23.87  ? 225 VAL B C   1 
ATOM   5452  O O   . VAL B 1 225 ? 121.132 155.463 96.090  1.00 23.87  ? 225 VAL B O   1 
ATOM   5453  C CB  . VAL B 1 225 ? 120.668 153.434 98.155  1.00 23.87  ? 225 VAL B CB  1 
ATOM   5454  C CG1 . VAL B 1 225 ? 120.958 154.418 99.271  1.00 23.87  ? 225 VAL B CG1 1 
ATOM   5455  C CG2 . VAL B 1 225 ? 120.215 152.105 98.729  1.00 23.87  ? 225 VAL B CG2 1 
ATOM   5456  N N   . ARG B 1 226 ? 119.173 156.356 96.784  1.00 23.80  ? 226 ARG B N   1 
ATOM   5457  C CA  . ARG B 1 226 ? 119.413 157.688 96.226  1.00 23.80  ? 226 ARG B CA  1 
ATOM   5458  C C   . ARG B 1 226 ? 119.675 157.625 94.722  1.00 23.80  ? 226 ARG B C   1 
ATOM   5459  O O   . ARG B 1 226 ? 120.522 158.344 94.189  1.00 23.80  ? 226 ARG B O   1 
ATOM   5460  C CB  . ARG B 1 226 ? 120.559 158.397 96.950  1.00 23.80  ? 226 ARG B CB  1 
ATOM   5461  C CG  . ARG B 1 226 ? 120.216 158.839 98.362  1.00 23.80  ? 226 ARG B CG  1 
ATOM   5462  C CD  . ARG B 1 226 ? 121.398 159.517 99.032  1.00 23.80  ? 226 ARG B CD  1 
ATOM   5463  N NE  . ARG B 1 226 ? 122.402 158.558 99.476  1.00 23.80  ? 226 ARG B NE  1 
ATOM   5464  C CZ  . ARG B 1 226 ? 122.280 157.786 100.547 1.00 23.80  ? 226 ARG B CZ  1 
ATOM   5465  N NH1 . ARG B 1 226 ? 121.205 157.833 101.314 1.00 23.80  ? 226 ARG B NH1 1 
ATOM   5466  N NH2 . ARG B 1 226 ? 123.264 156.947 100.856 1.00 23.80  ? 226 ARG B NH2 1 
ATOM   5467  N N   . GLY B 1 227 ? 118.939 156.757 94.031  1.00 25.67  ? 227 GLY B N   1 
ATOM   5468  C CA  . GLY B 1 227 ? 118.999 156.667 92.589  1.00 25.67  ? 227 GLY B CA  1 
ATOM   5469  C C   . GLY B 1 227 ? 120.059 155.746 92.026  1.00 25.67  ? 227 GLY B C   1 
ATOM   5470  O O   . GLY B 1 227 ? 120.178 155.651 90.798  1.00 25.67  ? 227 GLY B O   1 
ATOM   5471  N N   . GLN B 1 228 ? 120.826 155.062 92.869  1.00 24.45  ? 228 GLN B N   1 
ATOM   5472  C CA  . GLN B 1 228 ? 121.943 154.239 92.425  1.00 24.45  ? 228 GLN B CA  1 
ATOM   5473  C C   . GLN B 1 228 ? 121.701 152.785 92.797  1.00 24.45  ? 228 GLN B C   1 
ATOM   5474  O O   . GLN B 1 228 ? 121.330 152.484 93.936  1.00 24.45  ? 228 GLN B O   1 
ATOM   5475  C CB  . GLN B 1 228 ? 123.261 154.722 93.039  1.00 24.45  ? 228 GLN B CB  1 
ATOM   5476  C CG  . GLN B 1 228 ? 123.469 156.225 92.981  1.00 24.45  ? 228 GLN B CG  1 
ATOM   5477  C CD  . GLN B 1 228 ? 123.557 156.752 91.564  1.00 24.45  ? 228 GLN B CD  1 
ATOM   5478  O OE1 . GLN B 1 228 ? 124.100 156.095 90.678  1.00 24.45  ? 228 GLN B OE1 1 
ATOM   5479  N NE2 . GLN B 1 228 ? 123.024 157.945 91.343  1.00 24.45  ? 228 GLN B NE2 1 
ATOM   5480  N N   . SER B 1 229 ? 121.913 151.888 91.835  1.00 23.43  ? 229 SER B N   1 
ATOM   5481  C CA  . SER B 1 229 ? 121.882 150.452 92.074  1.00 23.43  ? 229 SER B CA  1 
ATOM   5482  C C   . SER B 1 229 ? 123.278 149.855 92.197  1.00 23.43  ? 229 SER B C   1 
ATOM   5483  O O   . SER B 1 229 ? 123.415 148.630 92.259  1.00 23.43  ? 229 SER B O   1 
ATOM   5484  C CB  . SER B 1 229 ? 121.106 149.746 90.962  1.00 23.43  ? 229 SER B CB  1 
ATOM   5485  O OG  . SER B 1 229 ? 121.557 150.157 89.685  1.00 23.43  ? 229 SER B OG  1 
ATOM   5486  N N   . SER B 1 230 ? 124.312 150.690 92.226  1.00 22.45  ? 230 SER B N   1 
ATOM   5487  C CA  . SER B 1 230 ? 125.689 150.258 92.400  1.00 22.45  ? 230 SER B CA  1 
ATOM   5488  C C   . SER B 1 230 ? 126.166 150.581 93.810  1.00 22.45  ? 230 SER B C   1 
ATOM   5489  O O   . SER B 1 230 ? 125.577 151.400 94.517  1.00 22.45  ? 230 SER B O   1 
ATOM   5490  C CB  . SER B 1 230 ? 126.600 150.931 91.371  1.00 22.45  ? 230 SER B CB  1 
ATOM   5491  O OG  . SER B 1 230 ? 126.118 150.729 90.056  1.00 22.45  ? 230 SER B OG  1 
ATOM   5492  N N   . ARG B 1 231 ? 127.251 149.925 94.214  1.00 21.11  ? 231 ARG B N   1 
ATOM   5493  C CA  . ARG B 1 231 ? 127.810 150.096 95.546  1.00 21.11  ? 231 ARG B CA  1 
ATOM   5494  C C   . ARG B 1 231 ? 129.315 150.303 95.453  1.00 21.11  ? 231 ARG B C   1 
ATOM   5495  O O   . ARG B 1 231 ? 129.925 150.153 94.392  1.00 21.11  ? 231 ARG B O   1 
ATOM   5496  C CB  . ARG B 1 231 ? 127.500 148.891 96.447  1.00 21.11  ? 231 ARG B CB  1 
ATOM   5497  C CG  . ARG B 1 231 ? 126.023 148.592 96.609  1.00 21.11  ? 231 ARG B CG  1 
ATOM   5498  C CD  . ARG B 1 231 ? 125.314 149.640 97.442  1.00 21.11  ? 231 ARG B CD  1 
ATOM   5499  N NE  . ARG B 1 231 ? 123.926 149.274 97.698  1.00 21.11  ? 231 ARG B NE  1 
ATOM   5500  C CZ  . ARG B 1 231 ? 122.894 149.702 96.985  1.00 21.11  ? 231 ARG B CZ  1 
ATOM   5501  N NH1 . ARG B 1 231 ? 123.055 150.510 95.951  1.00 21.11  ? 231 ARG B NH1 1 
ATOM   5502  N NH2 . ARG B 1 231 ? 121.668 149.309 97.317  1.00 21.11  ? 231 ARG B NH2 1 
ATOM   5503  N N   . ILE B 1 232 ? 129.908 150.661 96.589  1.00 19.20  ? 232 ILE B N   1 
ATOM   5504  C CA  . ILE B 1 232 ? 131.351 150.822 96.724  1.00 19.20  ? 232 ILE B CA  1 
ATOM   5505  C C   . ILE B 1 232 ? 131.777 150.169 98.031  1.00 19.20  ? 232 ILE B C   1 
ATOM   5506  O O   . ILE B 1 232 ? 131.173 150.418 99.078  1.00 19.20  ? 232 ILE B O   1 
ATOM   5507  C CB  . ILE B 1 232 ? 131.767 152.307 96.692  1.00 19.20  ? 232 ILE B CB  1 
ATOM   5508  C CG1 . ILE B 1 232 ? 131.748 152.835 95.257  1.00 19.20  ? 232 ILE B CG1 1 
ATOM   5509  C CG2 . ILE B 1 232 ? 133.144 152.500 97.301  1.00 19.20  ? 232 ILE B CG2 1 
ATOM   5510  C CD1 . ILE B 1 232 ? 131.846 154.336 95.158  1.00 19.20  ? 232 ILE B CD1 1 
ATOM   5511  N N   . SER B 1 233 ? 132.808 149.331 97.974  1.00 19.42  ? 233 SER B N   1 
ATOM   5512  C CA  . SER B 1 233 ? 133.332 148.657 99.155  1.00 19.42  ? 233 SER B CA  1 
ATOM   5513  C C   . SER B 1 233 ? 134.585 149.371 99.642  1.00 19.42  ? 233 SER B C   1 
ATOM   5514  O O   . SER B 1 233 ? 135.401 149.825 98.838  1.00 19.42  ? 233 SER B O   1 
ATOM   5515  C CB  . SER B 1 233 ? 133.645 147.191 98.857  1.00 19.42  ? 233 SER B CB  1 
ATOM   5516  O OG  . SER B 1 233 ? 132.457 146.444 98.672  1.00 19.42  ? 233 SER B OG  1 
ATOM   5517  N N   . ILE B 1 234 ? 134.735 149.459 100.961 1.00 17.22  ? 234 ILE B N   1 
ATOM   5518  C CA  . ILE B 1 234 ? 135.795 150.237 101.595 1.00 17.22  ? 234 ILE B CA  1 
ATOM   5519  C C   . ILE B 1 234 ? 136.807 149.283 102.216 1.00 17.22  ? 234 ILE B C   1 
ATOM   5520  O O   . ILE B 1 234 ? 136.431 148.349 102.933 1.00 17.22  ? 234 ILE B O   1 
ATOM   5521  C CB  . ILE B 1 234 ? 135.226 151.201 102.650 1.00 17.22  ? 234 ILE B CB  1 
ATOM   5522  C CG1 . ILE B 1 234 ? 134.196 152.137 102.015 1.00 17.22  ? 234 ILE B CG1 1 
ATOM   5523  C CG2 . ILE B 1 234 ? 136.338 152.005 103.300 1.00 17.22  ? 234 ILE B CG2 1 
ATOM   5524  C CD1 . ILE B 1 234 ? 134.755 153.000 100.908 1.00 17.22  ? 234 ILE B CD1 1 
ATOM   5525  N N   . TYR B 1 235 ? 138.088 149.522 101.938 1.00 19.55  ? 235 TYR B N   1 
ATOM   5526  C CA  . TYR B 1 235 ? 139.186 148.741 102.489 1.00 19.55  ? 235 TYR B CA  1 
ATOM   5527  C C   . TYR B 1 235 ? 140.254 149.688 103.017 1.00 19.55  ? 235 TYR B C   1 
ATOM   5528  O O   . TYR B 1 235 ? 140.308 150.861 102.642 1.00 19.55  ? 235 TYR B O   1 
ATOM   5529  C CB  . TYR B 1 235 ? 139.786 147.793 101.440 1.00 19.55  ? 235 TYR B CB  1 
ATOM   5530  C CG  . TYR B 1 235 ? 138.784 146.837 100.836 1.00 19.55  ? 235 TYR B CG  1 
ATOM   5531  C CD1 . TYR B 1 235 ? 138.067 147.178 99.699  1.00 19.55  ? 235 TYR B CD1 1 
ATOM   5532  C CD2 . TYR B 1 235 ? 138.554 145.594 101.406 1.00 19.55  ? 235 TYR B CD2 1 
ATOM   5533  C CE1 . TYR B 1 235 ? 137.149 146.310 99.148  1.00 19.55  ? 235 TYR B CE1 1 
ATOM   5534  C CE2 . TYR B 1 235 ? 137.638 144.719 100.862 1.00 19.55  ? 235 TYR B CE2 1 
ATOM   5535  C CZ  . TYR B 1 235 ? 136.938 145.082 99.734  1.00 19.55  ? 235 TYR B CZ  1 
ATOM   5536  O OH  . TYR B 1 235 ? 136.026 144.211 99.188  1.00 19.55  ? 235 TYR B OH  1 
ATOM   5537  N N   . TRP B 1 236 ? 141.108 149.172 103.901 1.00 17.89  ? 236 TRP B N   1 
ATOM   5538  C CA  . TRP B 1 236 ? 142.141 149.989 104.524 1.00 17.89  ? 236 TRP B CA  1 
ATOM   5539  C C   . TRP B 1 236 ? 143.456 149.221 104.585 1.00 17.89  ? 236 TRP B C   1 
ATOM   5540  O O   . TRP B 1 236 ? 143.486 147.989 104.550 1.00 17.89  ? 236 TRP B O   1 
ATOM   5541  C CB  . TRP B 1 236 ? 141.720 150.461 105.926 1.00 17.89  ? 236 TRP B CB  1 
ATOM   5542  C CG  . TRP B 1 236 ? 141.846 149.433 107.014 1.00 17.89  ? 236 TRP B CG  1 
ATOM   5543  C CD1 . TRP B 1 236 ? 142.957 149.151 107.754 1.00 17.89  ? 236 TRP B CD1 1 
ATOM   5544  C CD2 . TRP B 1 236 ? 140.813 148.568 107.498 1.00 17.89  ? 236 TRP B CD2 1 
ATOM   5545  N NE1 . TRP B 1 236 ? 142.683 148.157 108.659 1.00 17.89  ? 236 TRP B NE1 1 
ATOM   5546  C CE2 . TRP B 1 236 ? 141.372 147.783 108.523 1.00 17.89  ? 236 TRP B CE2 1 
ATOM   5547  C CE3 . TRP B 1 236 ? 139.470 148.378 107.159 1.00 17.89  ? 236 TRP B CE3 1 
ATOM   5548  C CZ2 . TRP B 1 236 ? 140.637 146.823 109.212 1.00 17.89  ? 236 TRP B CZ2 1 
ATOM   5549  C CZ3 . TRP B 1 236 ? 138.743 147.425 107.845 1.00 17.89  ? 236 TRP B CZ3 1 
ATOM   5550  C CH2 . TRP B 1 236 ? 139.327 146.660 108.859 1.00 17.89  ? 236 TRP B CH2 1 
ATOM   5551  N N   . THR B 1 237 ? 144.549 149.979 104.674 1.00 19.72  ? 237 THR B N   1 
ATOM   5552  C CA  . THR B 1 237 ? 145.898 149.430 104.719 1.00 19.72  ? 237 THR B CA  1 
ATOM   5553  C C   . THR B 1 237 ? 146.755 150.303 105.626 1.00 19.72  ? 237 THR B C   1 
ATOM   5554  O O   . THR B 1 237 ? 146.577 151.523 105.667 1.00 19.72  ? 237 THR B O   1 
ATOM   5555  C CB  . THR B 1 237 ? 146.516 149.354 103.317 1.00 19.72  ? 237 THR B CB  1 
ATOM   5556  O OG1 . THR B 1 237 ? 145.607 148.699 102.426 1.00 19.72  ? 237 THR B OG1 1 
ATOM   5557  C CG2 . THR B 1 237 ? 147.825 148.582 103.340 1.00 19.72  ? 237 THR B CG2 1 
ATOM   5558  N N   . ILE B 1 238 ? 147.683 149.676 106.346 1.00 23.69  ? 238 ILE B N   1 
ATOM   5559  C CA  . ILE B 1 238 ? 148.577 150.367 107.270 1.00 23.69  ? 238 ILE B CA  1 
ATOM   5560  C C   . ILE B 1 238 ? 150.015 150.119 106.833 1.00 23.69  ? 238 ILE B C   1 
ATOM   5561  O O   . ILE B 1 238 ? 150.405 148.972 106.587 1.00 23.69  ? 238 ILE B O   1 
ATOM   5562  C CB  . ILE B 1 238 ? 148.357 149.909 108.723 1.00 23.69  ? 238 ILE B CB  1 
ATOM   5563  C CG1 . ILE B 1 238 ? 147.074 150.524 109.282 1.00 23.69  ? 238 ILE B CG1 1 
ATOM   5564  C CG2 . ILE B 1 238 ? 149.542 150.289 109.595 1.00 23.69  ? 238 ILE B CG2 1 
ATOM   5565  C CD1 . ILE B 1 238 ? 146.660 149.963 110.612 1.00 23.69  ? 238 ILE B CD1 1 
ATOM   5566  N N   . VAL B 1 239 ? 150.799 151.192 106.743 1.00 25.23  ? 239 VAL B N   1 
ATOM   5567  C CA  . VAL B 1 239 ? 152.186 151.134 106.292 1.00 25.23  ? 239 VAL B CA  1 
ATOM   5568  C C   . VAL B 1 239 ? 153.088 151.533 107.453 1.00 25.23  ? 239 VAL B C   1 
ATOM   5569  O O   . VAL B 1 239 ? 152.968 152.642 107.988 1.00 25.23  ? 239 VAL B O   1 
ATOM   5570  C CB  . VAL B 1 239 ? 152.424 152.044 105.077 1.00 25.23  ? 239 VAL B CB  1 
ATOM   5571  C CG1 . VAL B 1 239 ? 153.832 151.861 104.544 1.00 25.23  ? 239 VAL B CG1 1 
ATOM   5572  C CG2 . VAL B 1 239 ? 151.400 151.756 103.994 1.00 25.23  ? 239 VAL B CG2 1 
ATOM   5573  N N   . LYS B 1 240 ? 153.992 150.634 107.834 1.00 29.77  ? 240 LYS B N   1 
ATOM   5574  C CA  . LYS B 1 240 ? 154.953 150.884 108.896 1.00 29.77  ? 240 LYS B CA  1 
ATOM   5575  C C   . LYS B 1 240 ? 156.104 151.749 108.391 1.00 29.77  ? 240 LYS B C   1 
ATOM   5576  O O   . LYS B 1 240 ? 156.355 151.820 107.186 1.00 29.77  ? 240 LYS B O   1 
ATOM   5577  C CB  . LYS B 1 240 ? 155.489 149.561 109.436 1.00 29.77  ? 240 LYS B CB  1 
ATOM   5578  C CG  . LYS B 1 240 ? 154.464 148.731 110.188 1.00 29.77  ? 240 LYS B CG  1 
ATOM   5579  C CD  . LYS B 1 240 ? 154.594 148.928 111.688 1.00 29.77  ? 240 LYS B CD  1 
ATOM   5580  C CE  . LYS B 1 240 ? 153.742 147.930 112.455 1.00 29.77  ? 240 LYS B CE  1 
ATOM   5581  N NZ  . LYS B 1 240 ? 153.404 148.419 113.820 1.00 29.77  ? 240 LYS B NZ  1 
ATOM   5582  N N   . PRO B 1 241 ? 156.810 152.436 109.291 1.00 29.60  ? 241 PRO B N   1 
ATOM   5583  C CA  . PRO B 1 241 ? 157.971 153.224 108.862 1.00 29.60  ? 241 PRO B CA  1 
ATOM   5584  C C   . PRO B 1 241 ? 159.019 152.347 108.191 1.00 29.60  ? 241 PRO B C   1 
ATOM   5585  O O   . PRO B 1 241 ? 159.310 151.238 108.642 1.00 29.60  ? 241 PRO B O   1 
ATOM   5586  C CB  . PRO B 1 241 ? 158.494 153.829 110.169 1.00 29.60  ? 241 PRO B CB  1 
ATOM   5587  C CG  . PRO B 1 241 ? 157.323 153.833 111.077 1.00 29.60  ? 241 PRO B CG  1 
ATOM   5588  C CD  . PRO B 1 241 ? 156.525 152.618 110.724 1.00 29.60  ? 241 PRO B CD  1 
ATOM   5589  N N   . GLY B 1 242 ? 159.591 152.863 107.107 1.00 30.35  ? 242 GLY B N   1 
ATOM   5590  C CA  . GLY B 1 242 ? 160.533 152.108 106.313 1.00 30.35  ? 242 GLY B CA  1 
ATOM   5591  C C   . GLY B 1 242 ? 159.914 151.164 105.307 1.00 30.35  ? 242 GLY B C   1 
ATOM   5592  O O   . GLY B 1 242 ? 160.655 150.474 104.595 1.00 30.35  ? 242 GLY B O   1 
ATOM   5593  N N   . ASP B 1 243 ? 158.587 151.107 105.223 1.00 29.80  ? 243 ASP B N   1 
ATOM   5594  C CA  . ASP B 1 243 ? 157.891 150.252 104.278 1.00 29.80  ? 243 ASP B CA  1 
ATOM   5595  C C   . ASP B 1 243 ? 157.472 151.065 103.055 1.00 29.80  ? 243 ASP B C   1 
ATOM   5596  O O   . ASP B 1 243 ? 157.713 152.271 102.962 1.00 29.80  ? 243 ASP B O   1 
ATOM   5597  C CB  . ASP B 1 243 ? 156.684 149.591 104.946 1.00 29.80  ? 243 ASP B CB  1 
ATOM   5598  C CG  . ASP B 1 243 ? 156.460 148.172 104.473 1.00 29.80  ? 243 ASP B CG  1 
ATOM   5599  O OD1 . ASP B 1 243 ? 156.745 147.887 103.293 1.00 29.80  ? 243 ASP B OD1 1 
ATOM   5600  O OD2 . ASP B 1 243 ? 155.993 147.341 105.280 1.00 29.80  ? 243 ASP B OD2 1 
ATOM   5601  N N   . VAL B 1 244 ? 156.833 150.392 102.102 1.00 28.26  ? 244 VAL B N   1 
ATOM   5602  C CA  . VAL B 1 244 ? 156.437 151.007 100.840 1.00 28.26  ? 244 VAL B CA  1 
ATOM   5603  C C   . VAL B 1 244 ? 155.052 150.497 100.460 1.00 28.26  ? 244 VAL B C   1 
ATOM   5604  O O   . VAL B 1 244 ? 154.685 149.363 100.783 1.00 28.26  ? 244 VAL B O   1 
ATOM   5605  C CB  . VAL B 1 244 ? 157.473 150.717 99.730  1.00 28.26  ? 244 VAL B CB  1 
ATOM   5606  C CG1 . VAL B 1 244 ? 157.518 149.234 99.407  1.00 28.26  ? 244 VAL B CG1 1 
ATOM   5607  C CG2 . VAL B 1 244 ? 157.186 151.538 98.485  1.00 28.26  ? 244 VAL B CG2 1 
ATOM   5608  N N   . LEU B 1 245 ? 154.279 151.346 99.789  1.00 24.51  ? 245 LEU B N   1 
ATOM   5609  C CA  . LEU B 1 245 ? 152.936 151.015 99.330  1.00 24.51  ? 245 LEU B CA  1 
ATOM   5610  C C   . LEU B 1 245 ? 152.921 150.963 97.810  1.00 24.51  ? 245 LEU B C   1 
ATOM   5611  O O   . LEU B 1 245 ? 153.455 151.860 97.151  1.00 24.51  ? 245 LEU B O   1 
ATOM   5612  C CB  . LEU B 1 245 ? 151.919 152.046 99.824  1.00 24.51  ? 245 LEU B CB  1 
ATOM   5613  C CG  . LEU B 1 245 ? 150.452 151.783 99.478  1.00 24.51  ? 245 LEU B CG  1 
ATOM   5614  C CD1 . LEU B 1 245 ? 149.930 150.562 100.216 1.00 24.51  ? 245 LEU B CD1 1 
ATOM   5615  C CD2 . LEU B 1 245 ? 149.600 153.002 99.768  1.00 24.51  ? 245 LEU B CD2 1 
ATOM   5616  N N   . VAL B 1 246 ? 152.311 149.917 97.257  1.00 23.48  ? 246 VAL B N   1 
ATOM   5617  C CA  . VAL B 1 246 ? 152.150 149.766 95.816  1.00 23.48  ? 246 VAL B CA  1 
ATOM   5618  C C   . VAL B 1 246 ? 150.679 149.514 95.524  1.00 23.48  ? 246 VAL B C   1 
ATOM   5619  O O   . VAL B 1 246 ? 150.046 148.677 96.176  1.00 23.48  ? 246 VAL B O   1 
ATOM   5620  C CB  . VAL B 1 246 ? 153.018 148.624 95.252  1.00 23.48  ? 246 VAL B CB  1 
ATOM   5621  C CG1 . VAL B 1 246 ? 152.792 148.472 93.757  1.00 23.48  ? 246 VAL B CG1 1 
ATOM   5622  C CG2 . VAL B 1 246 ? 154.486 148.883 95.535  1.00 23.48  ? 246 VAL B CG2 1 
ATOM   5623  N N   . ILE B 1 247 ? 150.135 150.242 94.553  1.00 23.57  ? 247 ILE B N   1 
ATOM   5624  C CA  . ILE B 1 247 ? 148.759 150.067 94.103  1.00 23.57  ? 247 ILE B CA  1 
ATOM   5625  C C   . ILE B 1 247 ? 148.795 149.670 92.636  1.00 23.57  ? 247 ILE B C   1 
ATOM   5626  O O   . ILE B 1 247 ? 149.353 150.396 91.804  1.00 23.57  ? 247 ILE B O   1 
ATOM   5627  C CB  . ILE B 1 247 ? 147.920 151.338 94.307  1.00 23.57  ? 247 ILE B CB  1 
ATOM   5628  C CG1 . ILE B 1 247 ? 147.840 151.690 95.793  1.00 23.57  ? 247 ILE B CG1 1 
ATOM   5629  C CG2 . ILE B 1 247 ? 146.529 151.158 93.724  1.00 23.57  ? 247 ILE B CG2 1 
ATOM   5630  C CD1 . ILE B 1 247 ? 147.391 153.104 96.058  1.00 23.57  ? 247 ILE B CD1 1 
ATOM   5631  N N   . ASN B 1 248 ? 148.203 148.521 92.320  1.00 25.60  ? 248 ASN B N   1 
ATOM   5632  C CA  . ASN B 1 248 ? 148.136 148.011 90.959  1.00 25.60  ? 248 ASN B CA  1 
ATOM   5633  C C   . ASN B 1 248 ? 146.680 147.736 90.622  1.00 25.60  ? 248 ASN B C   1 
ATOM   5634  O O   . ASN B 1 248 ? 145.979 147.071 91.391  1.00 25.60  ? 248 ASN B O   1 
ATOM   5635  C CB  . ASN B 1 248 ? 148.980 146.740 90.807  1.00 25.60  ? 248 ASN B CB  1 
ATOM   5636  C CG  . ASN B 1 248 ? 149.134 146.309 89.365  1.00 25.60  ? 248 ASN B CG  1 
ATOM   5637  O OD1 . ASN B 1 248 ? 148.337 145.527 88.850  1.00 25.60  ? 248 ASN B OD1 1 
ATOM   5638  N ND2 . ASN B 1 248 ? 150.166 146.816 88.704  1.00 25.60  ? 248 ASN B ND2 1 
ATOM   5639  N N   . SER B 1 249 ? 146.224 148.248 89.481  1.00 25.92  ? 249 SER B N   1 
ATOM   5640  C CA  . SER B 1 249 ? 144.820 148.123 89.121  1.00 25.92  ? 249 SER B CA  1 
ATOM   5641  C C   . SER B 1 249 ? 144.659 148.304 87.620  1.00 25.92  ? 249 SER B C   1 
ATOM   5642  O O   . SER B 1 249 ? 145.493 148.924 86.956  1.00 25.92  ? 249 SER B O   1 
ATOM   5643  C CB  . SER B 1 249 ? 143.959 149.140 89.877  1.00 25.92  ? 249 SER B CB  1 
ATOM   5644  O OG  . SER B 1 249 ? 142.666 149.241 89.308  1.00 25.92  ? 249 SER B OG  1 
ATOM   5645  N N   . ASN B 1 250 ? 143.565 147.747 87.095  1.00 26.93  ? 250 ASN B N   1 
ATOM   5646  C CA  . ASN B 1 250 ? 143.190 147.966 85.703  1.00 26.93  ? 250 ASN B CA  1 
ATOM   5647  C C   . ASN B 1 250 ? 141.700 148.263 85.559  1.00 26.93  ? 250 ASN B C   1 
ATOM   5648  O O   . ASN B 1 250 ? 141.126 148.007 84.494  1.00 26.93  ? 250 ASN B O   1 
ATOM   5649  C CB  . ASN B 1 250 ? 143.577 146.762 84.835  1.00 26.93  ? 250 ASN B CB  1 
ATOM   5650  C CG  . ASN B 1 250 ? 142.795 145.515 85.183  1.00 26.93  ? 250 ASN B CG  1 
ATOM   5651  O OD1 . ASN B 1 250 ? 142.513 145.253 86.350  1.00 26.93  ? 250 ASN B OD1 1 
ATOM   5652  N ND2 . ASN B 1 250 ? 142.445 144.734 84.169  1.00 26.93  ? 250 ASN B ND2 1 
ATOM   5653  N N   . GLY B 1 251 ? 141.069 148.793 86.591  1.00 25.39  ? 251 GLY B N   1 
ATOM   5654  C CA  . GLY B 1 251 ? 139.666 149.160 86.562  1.00 25.39  ? 251 GLY B CA  1 
ATOM   5655  C C   . GLY B 1 251 ? 139.049 149.038 87.943  1.00 25.39  ? 251 GLY B C   1 
ATOM   5656  O O   . GLY B 1 251 ? 139.505 148.283 88.797  1.00 25.39  ? 251 GLY B O   1 
ATOM   5657  N N   . ASN B 1 252 ? 137.994 149.827 88.168  1.00 24.17  ? 252 ASN B N   1 
ATOM   5658  C CA  . ASN B 1 252 ? 137.153 149.739 89.366  1.00 24.17  ? 252 ASN B CA  1 
ATOM   5659  C C   . ASN B 1 252 ? 137.901 150.158 90.632  1.00 24.17  ? 252 ASN B C   1 
ATOM   5660  O O   . ASN B 1 252 ? 137.713 149.569 91.696  1.00 24.17  ? 252 ASN B O   1 
ATOM   5661  C CB  . ASN B 1 252 ? 136.566 148.334 89.535  1.00 24.17  ? 252 ASN B CB  1 
ATOM   5662  C CG  . ASN B 1 252 ? 135.648 147.944 88.400  1.00 24.17  ? 252 ASN B CG  1 
ATOM   5663  O OD1 . ASN B 1 252 ? 136.097 147.684 87.286  1.00 24.17  ? 252 ASN B OD1 1 
ATOM   5664  N ND2 . ASN B 1 252 ? 134.353 147.900 88.676  1.00 24.17  ? 252 ASN B ND2 1 
ATOM   5665  N N   . LEU B 1 253 ? 138.744 151.181 90.529  1.00 21.85  ? 253 LEU B N   1 
ATOM   5666  C CA  . LEU B 1 253 ? 139.539 151.653 91.656  1.00 21.85  ? 253 LEU B CA  1 
ATOM   5667  C C   . LEU B 1 253 ? 139.017 152.997 92.145  1.00 21.85  ? 253 LEU B C   1 
ATOM   5668  O O   . LEU B 1 253 ? 138.834 153.925 91.350  1.00 21.85  ? 253 LEU B O   1 
ATOM   5669  C CB  . LEU B 1 253 ? 141.016 151.775 91.276  1.00 21.85  ? 253 LEU B CB  1 
ATOM   5670  C CG  . LEU B 1 253 ? 141.913 152.492 92.291  1.00 21.85  ? 253 LEU B CG  1 
ATOM   5671  C CD1 . LEU B 1 253 ? 142.228 151.594 93.475  1.00 21.85  ? 253 LEU B CD1 1 
ATOM   5672  C CD2 . LEU B 1 253 ? 143.193 152.981 91.637  1.00 21.85  ? 253 LEU B CD2 1 
ATOM   5673  N N   . ILE B 1 254 ? 138.776 153.094 93.449  1.00 20.14  ? 254 ILE B N   1 
ATOM   5674  C CA  . ILE B 1 254 ? 138.512 154.361 94.120  1.00 20.14  ? 254 ILE B CA  1 
ATOM   5675  C C   . ILE B 1 254 ? 139.795 154.721 94.861  1.00 20.14  ? 254 ILE B C   1 
ATOM   5676  O O   . ILE B 1 254 ? 140.073 154.196 95.942  1.00 20.14  ? 254 ILE B O   1 
ATOM   5677  C CB  . ILE B 1 254 ? 137.308 154.273 95.062  1.00 20.14  ? 254 ILE B CB  1 
ATOM   5678  C CG1 . ILE B 1 254 ? 136.117 153.621 94.354  1.00 20.14  ? 254 ILE B CG1 1 
ATOM   5679  C CG2 . ILE B 1 254 ? 136.934 155.652 95.579  1.00 20.14  ? 254 ILE B CG2 1 
ATOM   5680  C CD1 . ILE B 1 254 ? 135.447 154.504 93.331  1.00 20.14  ? 254 ILE B CD1 1 
ATOM   5681  N N   . ALA B 1 255 ? 140.579 155.620 94.277  1.00 19.96  ? 255 ALA B N   1 
ATOM   5682  C CA  . ALA B 1 255 ? 141.935 155.849 94.745  1.00 19.96  ? 255 ALA B CA  1 
ATOM   5683  C C   . ALA B 1 255 ? 141.950 156.696 96.017  1.00 19.96  ? 255 ALA B C   1 
ATOM   5684  O O   . ALA B 1 255 ? 141.054 157.513 96.241  1.00 19.96  ? 255 ALA B O   1 
ATOM   5685  C CB  . ALA B 1 255 ? 142.755 156.536 93.659  1.00 19.96  ? 255 ALA B CB  1 
ATOM   5686  N N   . PRO B 1 256 ? 142.956 156.515 96.867  1.00 20.03  ? 256 PRO B N   1 
ATOM   5687  C CA  . PRO B 1 256 ? 143.119 157.397 98.024  1.00 20.03  ? 256 PRO B CA  1 
ATOM   5688  C C   . PRO B 1 256 ? 143.767 158.719 97.637  1.00 20.03  ? 256 PRO B C   1 
ATOM   5689  O O   . PRO B 1 256 ? 144.467 158.836 96.630  1.00 20.03  ? 256 PRO B O   1 
ATOM   5690  C CB  . PRO B 1 256 ? 144.032 156.592 98.955  1.00 20.03  ? 256 PRO B CB  1 
ATOM   5691  C CG  . PRO B 1 256 ? 144.815 155.725 98.046  1.00 20.03  ? 256 PRO B CG  1 
ATOM   5692  C CD  . PRO B 1 256 ? 143.935 155.413 96.866  1.00 20.03  ? 256 PRO B CD  1 
ATOM   5693  N N   . ARG B 1 257 ? 143.514 159.728 98.469  1.00 20.37  ? 257 ARG B N   1 
ATOM   5694  C CA  . ARG B 1 257 ? 144.096 161.049 98.285  1.00 20.37  ? 257 ARG B CA  1 
ATOM   5695  C C   . ARG B 1 257 ? 145.232 161.343 99.253  1.00 20.37  ? 257 ARG B C   1 
ATOM   5696  O O   . ARG B 1 257 ? 145.860 162.401 99.141  1.00 20.37  ? 257 ARG B O   1 
ATOM   5697  C CB  . ARG B 1 257 ? 143.016 162.130 98.430  1.00 20.37  ? 257 ARG B CB  1 
ATOM   5698  C CG  . ARG B 1 257 ? 142.056 162.213 97.258  1.00 20.37  ? 257 ARG B CG  1 
ATOM   5699  C CD  . ARG B 1 257 ? 141.204 163.462 97.342  1.00 20.37  ? 257 ARG B CD  1 
ATOM   5700  N NE  . ARG B 1 257 ? 140.157 163.488 96.329  1.00 20.37  ? 257 ARG B NE  1 
ATOM   5701  C CZ  . ARG B 1 257 ? 140.290 164.033 95.128  1.00 20.37  ? 257 ARG B CZ  1 
ATOM   5702  N NH1 . ARG B 1 257 ? 141.426 164.588 94.743  1.00 20.37  ? 257 ARG B NH1 1 
ATOM   5703  N NH2 . ARG B 1 257 ? 139.257 164.018 94.291  1.00 20.37  ? 257 ARG B NH2 1 
ATOM   5704  N N   . GLY B 1 258 ? 145.513 160.441 100.187 1.00 19.34  ? 258 GLY B N   1 
ATOM   5705  C CA  . GLY B 1 258 ? 146.529 160.688 101.192 1.00 19.34  ? 258 GLY B CA  1 
ATOM   5706  C C   . GLY B 1 258 ? 146.446 159.635 102.278 1.00 19.34  ? 258 GLY B C   1 
ATOM   5707  O O   . GLY B 1 258 ? 145.898 158.553 102.064 1.00 19.34  ? 258 GLY B O   1 
ATOM   5708  N N   . PHE B 1 259 ? 146.987 159.970 103.446 1.00 19.14  ? 259 PHE B N   1 
ATOM   5709  C CA  . PHE B 1 259 ? 146.993 159.052 104.574 1.00 19.14  ? 259 PHE B CA  1 
ATOM   5710  C C   . PHE B 1 259 ? 146.485 159.750 105.828 1.00 19.14  ? 259 PHE B C   1 
ATOM   5711  O O   . PHE B 1 259 ? 146.477 160.979 105.925 1.00 19.14  ? 259 PHE B O   1 
ATOM   5712  C CB  . PHE B 1 259 ? 148.395 158.465 104.821 1.00 19.14  ? 259 PHE B CB  1 
ATOM   5713  C CG  . PHE B 1 259 ? 149.421 159.481 105.240 1.00 19.14  ? 259 PHE B CG  1 
ATOM   5714  C CD1 . PHE B 1 259 ? 150.157 160.171 104.293 1.00 19.14  ? 259 PHE B CD1 1 
ATOM   5715  C CD2 . PHE B 1 259 ? 149.663 159.732 106.580 1.00 19.14  ? 259 PHE B CD2 1 
ATOM   5716  C CE1 . PHE B 1 259 ? 151.103 161.099 104.673 1.00 19.14  ? 259 PHE B CE1 1 
ATOM   5717  C CE2 . PHE B 1 259 ? 150.606 160.659 106.965 1.00 19.14  ? 259 PHE B CE2 1 
ATOM   5718  C CZ  . PHE B 1 259 ? 151.328 161.343 106.011 1.00 19.14  ? 259 PHE B CZ  1 
ATOM   5719  N N   . PHE B 1 260 ? 146.049 158.938 106.785 1.00 20.63  ? 260 PHE B N   1 
ATOM   5720  C CA  . PHE B 1 260 ? 145.637 159.399 108.102 1.00 20.63  ? 260 PHE B CA  1 
ATOM   5721  C C   . PHE B 1 260 ? 146.734 159.103 109.115 1.00 20.63  ? 260 PHE B C   1 
ATOM   5722  O O   . PHE B 1 260 ? 147.303 158.008 109.125 1.00 20.63  ? 260 PHE B O   1 
ATOM   5723  C CB  . PHE B 1 260 ? 144.342 158.717 108.550 1.00 20.63  ? 260 PHE B CB  1 
ATOM   5724  C CG  . PHE B 1 260 ? 143.110 159.224 107.862 1.00 20.63  ? 260 PHE B CG  1 
ATOM   5725  C CD1 . PHE B 1 260 ? 142.410 160.302 108.374 1.00 20.63  ? 260 PHE B CD1 1 
ATOM   5726  C CD2 . PHE B 1 260 ? 142.642 158.613 106.712 1.00 20.63  ? 260 PHE B CD2 1 
ATOM   5727  C CE1 . PHE B 1 260 ? 141.274 160.767 107.747 1.00 20.63  ? 260 PHE B CE1 1 
ATOM   5728  C CE2 . PHE B 1 260 ? 141.507 159.075 106.081 1.00 20.63  ? 260 PHE B CE2 1 
ATOM   5729  C CZ  . PHE B 1 260 ? 140.822 160.153 106.599 1.00 20.63  ? 260 PHE B CZ  1 
ATOM   5730  N N   . LYS B 1 261 ? 147.030 160.082 109.966 1.00 25.92  ? 261 LYS B N   1 
ATOM   5731  C CA  . LYS B 1 261 ? 147.935 159.838 111.080 1.00 25.92  ? 261 LYS B CA  1 
ATOM   5732  C C   . LYS B 1 261 ? 147.229 159.001 112.137 1.00 25.92  ? 261 LYS B C   1 
ATOM   5733  O O   . LYS B 1 261 ? 146.172 159.386 112.645 1.00 25.92  ? 261 LYS B O   1 
ATOM   5734  C CB  . LYS B 1 261 ? 148.412 161.156 111.686 1.00 25.92  ? 261 LYS B CB  1 
ATOM   5735  C CG  . LYS B 1 261 ? 149.373 161.946 110.819 1.00 25.92  ? 261 LYS B CG  1 
ATOM   5736  C CD  . LYS B 1 261 ? 149.798 163.219 111.529 1.00 25.92  ? 261 LYS B CD  1 
ATOM   5737  C CE  . LYS B 1 261 ? 150.588 164.140 110.617 1.00 25.92  ? 261 LYS B CE  1 
ATOM   5738  N NZ  . LYS B 1 261 ? 151.982 163.668 110.421 1.00 25.92  ? 261 LYS B NZ  1 
ATOM   5739  N N   . ILE B 1 262 ? 147.815 157.856 112.471 1.00 26.59  ? 262 ILE B N   1 
ATOM   5740  C CA  . ILE B 1 262 ? 147.248 156.931 113.443 1.00 26.59  ? 262 ILE B CA  1 
ATOM   5741  C C   . ILE B 1 262 ? 148.116 156.958 114.695 1.00 26.59  ? 262 ILE B C   1 
ATOM   5742  O O   . ILE B 1 262 ? 149.345 156.849 114.612 1.00 26.59  ? 262 ILE B O   1 
ATOM   5743  C CB  . ILE B 1 262 ? 147.114 155.506 112.866 1.00 26.59  ? 262 ILE B CB  1 
ATOM   5744  C CG1 . ILE B 1 262 ? 146.391 154.586 113.850 1.00 26.59  ? 262 ILE B CG1 1 
ATOM   5745  C CG2 . ILE B 1 262 ? 148.459 154.940 112.434 1.00 26.59  ? 262 ILE B CG2 1 
ATOM   5746  C CD1 . ILE B 1 262 ? 145.970 153.270 113.246 1.00 26.59  ? 262 ILE B CD1 1 
ATOM   5747  N N   . ARG B 1 263 ? 147.477 157.140 115.846 1.00 30.08  ? 263 ARG B N   1 
ATOM   5748  C CA  . ARG B 1 263 ? 148.162 157.326 117.114 1.00 30.08  ? 263 ARG B CA  1 
ATOM   5749  C C   . ARG B 1 263 ? 147.696 156.285 118.122 1.00 30.08  ? 263 ARG B C   1 
ATOM   5750  O O   . ARG B 1 263 ? 146.768 155.511 117.877 1.00 30.08  ? 263 ARG B O   1 
ATOM   5751  C CB  . ARG B 1 263 ? 147.918 158.735 117.668 1.00 30.08  ? 263 ARG B CB  1 
ATOM   5752  C CG  . ARG B 1 263 ? 148.536 159.847 116.845 1.00 30.08  ? 263 ARG B CG  1 
ATOM   5753  C CD  . ARG B 1 263 ? 147.871 161.178 117.144 1.00 30.08  ? 263 ARG B CD  1 
ATOM   5754  N NE  . ARG B 1 263 ? 148.766 162.305 116.913 1.00 30.08  ? 263 ARG B NE  1 
ATOM   5755  C CZ  . ARG B 1 263 ? 148.758 163.055 115.820 1.00 30.08  ? 263 ARG B CZ  1 
ATOM   5756  N NH1 . ARG B 1 263 ? 147.914 162.824 114.829 1.00 30.08  ? 263 ARG B NH1 1 
ATOM   5757  N NH2 . ARG B 1 263 ? 149.621 164.062 115.718 1.00 30.08  ? 263 ARG B NH2 1 
ATOM   5758  N N   . THR B 1 264 ? 148.363 156.278 119.272 1.00 33.98  ? 264 THR B N   1 
ATOM   5759  C CA  . THR B 1 264 ? 148.008 155.424 120.396 1.00 33.98  ? 264 THR B CA  1 
ATOM   5760  C C   . THR B 1 264 ? 147.614 156.306 121.571 1.00 33.98  ? 264 THR B C   1 
ATOM   5761  O O   . THR B 1 264 ? 148.287 157.303 121.855 1.00 33.98  ? 264 THR B O   1 
ATOM   5762  C CB  . THR B 1 264 ? 149.172 154.508 120.782 1.00 33.98  ? 264 THR B CB  1 
ATOM   5763  O OG1 . THR B 1 264 ? 149.649 153.822 119.619 1.00 33.98  ? 264 THR B OG1 1 
ATOM   5764  C CG2 . THR B 1 264 ? 148.726 153.485 121.813 1.00 33.98  ? 264 THR B CG2 1 
ATOM   5765  N N   . GLY B 1 265 ? 146.526 155.947 122.245 1.00 33.65  ? 265 GLY B N   1 
ATOM   5766  C CA  . GLY B 1 265 ? 146.044 156.754 123.347 1.00 33.65  ? 265 GLY B CA  1 
ATOM   5767  C C   . GLY B 1 265 ? 144.888 156.139 124.106 1.00 33.65  ? 265 GLY B C   1 
ATOM   5768  O O   . GLY B 1 265 ? 144.760 154.914 124.175 1.00 33.65  ? 265 GLY B O   1 
ATOM   5769  N N   . ARG B 1 266 ? 144.035 156.988 124.678 1.00 32.64  ? 266 ARG B N   1 
ATOM   5770  C CA  . ARG B 1 266 ? 142.937 156.553 125.531 1.00 32.64  ? 266 ARG B CA  1 
ATOM   5771  C C   . ARG B 1 266 ? 141.585 157.046 125.020 1.00 32.64  ? 266 ARG B C   1 
ATOM   5772  O O   . ARG B 1 266 ? 140.668 157.293 125.805 1.00 32.64  ? 266 ARG B O   1 
ATOM   5773  C CB  . ARG B 1 266 ? 143.175 157.011 126.969 1.00 32.64  ? 266 ARG B CB  1 
ATOM   5774  C CG  . ARG B 1 266 ? 143.172 158.518 127.154 1.00 32.64  ? 266 ARG B CG  1 
ATOM   5775  C CD  . ARG B 1 266 ? 143.385 158.899 128.606 1.00 32.64  ? 266 ARG B CD  1 
ATOM   5776  N NE  . ARG B 1 266 ? 143.463 160.344 128.781 1.00 32.64  ? 266 ARG B NE  1 
ATOM   5777  C CZ  . ARG B 1 266 ? 142.414 161.132 128.973 1.00 32.64  ? 266 ARG B CZ  1 
ATOM   5778  N NH1 . ARG B 1 266 ? 141.184 160.646 129.016 1.00 32.64  ? 266 ARG B NH1 1 
ATOM   5779  N NH2 . ARG B 1 266 ? 142.603 162.439 129.125 1.00 32.64  ? 266 ARG B NH2 1 
ATOM   5780  N N   . SER B 1 267 ? 141.441 157.176 123.706 1.00 25.05  ? 267 SER B N   1 
ATOM   5781  C CA  . SER B 1 267 ? 140.194 157.627 123.108 1.00 25.05  ? 267 SER B CA  1 
ATOM   5782  C C   . SER B 1 267 ? 139.250 156.450 122.876 1.00 25.05  ? 267 SER B C   1 
ATOM   5783  O O   . SER B 1 267 ? 139.662 155.289 122.835 1.00 25.05  ? 267 SER B O   1 
ATOM   5784  C CB  . SER B 1 267 ? 140.463 158.352 121.791 1.00 25.05  ? 267 SER B CB  1 
ATOM   5785  O OG  . SER B 1 267 ? 141.100 159.596 122.016 1.00 25.05  ? 267 SER B OG  1 
ATOM   5786  N N   . SER B 1 268 ? 137.967 156.767 122.723 1.00 22.40  ? 268 SER B N   1 
ATOM   5787  C CA  . SER B 1 268 ? 136.942 155.751 122.513 1.00 22.40  ? 268 SER B CA  1 
ATOM   5788  C C   . SER B 1 268 ? 135.724 156.406 121.872 1.00 22.40  ? 268 SER B C   1 
ATOM   5789  O O   . SER B 1 268 ? 135.732 157.596 121.546 1.00 22.40  ? 268 SER B O   1 
ATOM   5790  C CB  . SER B 1 268 ? 136.576 155.057 123.827 1.00 22.40  ? 268 SER B CB  1 
ATOM   5791  O OG  . SER B 1 268 ? 135.871 153.853 123.587 1.00 22.40  ? 268 SER B OG  1 
ATOM   5792  N N   . ILE B 1 269 ? 134.670 155.611 121.695 1.00 20.72  ? 269 ILE B N   1 
ATOM   5793  C CA  . ILE B 1 269 ? 133.425 156.061 121.084 1.00 20.72  ? 269 ILE B CA  1 
ATOM   5794  C C   . ILE B 1 269 ? 132.262 155.515 121.902 1.00 20.72  ? 269 ILE B C   1 
ATOM   5795  O O   . ILE B 1 269 ? 132.360 154.451 122.520 1.00 20.72  ? 269 ILE B O   1 
ATOM   5796  C CB  . ILE B 1 269 ? 133.329 155.619 119.603 1.00 20.72  ? 269 ILE B CB  1 
ATOM   5797  C CG1 . ILE B 1 269 ? 132.106 156.234 118.920 1.00 20.72  ? 269 ILE B CG1 1 
ATOM   5798  C CG2 . ILE B 1 269 ? 133.305 154.103 119.495 1.00 20.72  ? 269 ILE B CG2 1 
ATOM   5799  C CD1 . ILE B 1 269 ? 132.207 156.273 117.419 1.00 20.72  ? 269 ILE B CD1 1 
ATOM   5800  N N   . MET B 1 270 ? 131.155 156.256 121.912 1.00 21.90  ? 270 MET B N   1 
ATOM   5801  C CA  . MET B 1 270 ? 129.990 155.874 122.696 1.00 21.90  ? 270 MET B CA  1 
ATOM   5802  C C   . MET B 1 270 ? 128.722 156.271 121.955 1.00 21.90  ? 270 MET B C   1 
ATOM   5803  O O   . MET B 1 270 ? 128.679 157.298 121.273 1.00 21.90  ? 270 MET B O   1 
ATOM   5804  C CB  . MET B 1 270 ? 130.021 156.526 124.083 1.00 21.90  ? 270 MET B CB  1 
ATOM   5805  C CG  . MET B 1 270 ? 128.921 156.067 125.023 1.00 21.90  ? 270 MET B CG  1 
ATOM   5806  S SD  . MET B 1 270 ? 128.895 157.011 126.556 1.00 21.90  ? 270 MET B SD  1 
ATOM   5807  C CE  . MET B 1 270 ? 130.112 156.117 127.516 1.00 21.90  ? 270 MET B CE  1 
ATOM   5808  N N   . ARG B 1 271 ? 127.688 155.445 122.097 1.00 22.39  ? 271 ARG B N   1 
ATOM   5809  C CA  . ARG B 1 271 ? 126.364 155.729 121.556 1.00 22.39  ? 271 ARG B CA  1 
ATOM   5810  C C   . ARG B 1 271 ? 125.479 156.249 122.681 1.00 22.39  ? 271 ARG B C   1 
ATOM   5811  O O   . ARG B 1 271 ? 125.261 155.548 123.675 1.00 22.39  ? 271 ARG B O   1 
ATOM   5812  C CB  . ARG B 1 271 ? 125.743 154.481 120.930 1.00 22.39  ? 271 ARG B CB  1 
ATOM   5813  C CG  . ARG B 1 271 ? 126.514 153.888 119.768 1.00 22.39  ? 271 ARG B CG  1 
ATOM   5814  C CD  . ARG B 1 271 ? 125.768 152.696 119.192 1.00 22.39  ? 271 ARG B CD  1 
ATOM   5815  N NE  . ARG B 1 271 ? 126.472 152.077 118.075 1.00 22.39  ? 271 ARG B NE  1 
ATOM   5816  C CZ  . ARG B 1 271 ? 127.214 150.983 118.171 1.00 22.39  ? 271 ARG B CZ  1 
ATOM   5817  N NH1 . ARG B 1 271 ? 127.383 150.361 119.326 1.00 22.39  ? 271 ARG B NH1 1 
ATOM   5818  N NH2 . ARG B 1 271 ? 127.801 150.499 117.081 1.00 22.39  ? 271 ARG B NH2 1 
ATOM   5819  N N   . SER B 1 272 ? 124.964 157.465 122.522 1.00 25.90  ? 272 SER B N   1 
ATOM   5820  C CA  . SER B 1 272 ? 124.131 158.070 123.552 1.00 25.90  ? 272 SER B CA  1 
ATOM   5821  C C   . SER B 1 272 ? 123.275 159.158 122.925 1.00 25.90  ? 272 SER B C   1 
ATOM   5822  O O   . SER B 1 272 ? 123.568 159.653 121.834 1.00 25.90  ? 272 SER B O   1 
ATOM   5823  C CB  . SER B 1 272 ? 124.980 158.642 124.693 1.00 25.90  ? 272 SER B CB  1 
ATOM   5824  O OG  . SER B 1 272 ? 124.177 159.328 125.636 1.00 25.90  ? 272 SER B OG  1 
ATOM   5825  N N   . ASP B 1 273 ? 122.208 159.524 123.634 1.00 29.32  ? 273 ASP B N   1 
ATOM   5826  C CA  . ASP B 1 273 ? 121.322 160.604 123.217 1.00 29.32  ? 273 ASP B CA  1 
ATOM   5827  C C   . ASP B 1 273 ? 121.223 161.713 124.258 1.00 29.32  ? 273 ASP B C   1 
ATOM   5828  O O   . ASP B 1 273 ? 120.370 162.597 124.126 1.00 29.32  ? 273 ASP B O   1 
ATOM   5829  C CB  . ASP B 1 273 ? 119.924 160.061 122.905 1.00 29.32  ? 273 ASP B CB  1 
ATOM   5830  C CG  . ASP B 1 273 ? 119.808 159.527 121.492 1.00 29.32  ? 273 ASP B CG  1 
ATOM   5831  O OD1 . ASP B 1 273 ? 120.448 160.094 120.583 1.00 29.32  ? 273 ASP B OD1 1 
ATOM   5832  O OD2 . ASP B 1 273 ? 119.070 158.541 121.289 1.00 29.32  ? 273 ASP B OD2 1 
ATOM   5833  N N   . ALA B 1 274 ? 122.067 161.688 125.287 1.00 29.53  ? 274 ALA B N   1 
ATOM   5834  C CA  . ALA B 1 274 ? 122.021 162.696 126.337 1.00 29.53  ? 274 ALA B CA  1 
ATOM   5835  C C   . ALA B 1 274 ? 122.679 163.992 125.863 1.00 29.53  ? 274 ALA B C   1 
ATOM   5836  O O   . ALA B 1 274 ? 123.700 163.954 125.172 1.00 29.53  ? 274 ALA B O   1 
ATOM   5837  C CB  . ALA B 1 274 ? 122.720 162.192 127.595 1.00 29.53  ? 274 ALA B CB  1 
ATOM   5838  N N   . PRO B 1 275 ? 122.116 165.144 126.216 1.00 30.23  ? 275 PRO B N   1 
ATOM   5839  C CA  . PRO B 1 275 ? 122.743 166.417 125.848 1.00 30.23  ? 275 PRO B CA  1 
ATOM   5840  C C   . PRO B 1 275 ? 124.018 166.665 126.640 1.00 30.23  ? 275 PRO B C   1 
ATOM   5841  O O   . PRO B 1 275 ? 124.262 166.072 127.692 1.00 30.23  ? 275 PRO B O   1 
ATOM   5842  C CB  . PRO B 1 275 ? 121.670 167.457 126.186 1.00 30.23  ? 275 PRO B CB  1 
ATOM   5843  C CG  . PRO B 1 275 ? 120.785 166.788 127.175 1.00 30.23  ? 275 PRO B CG  1 
ATOM   5844  C CD  . PRO B 1 275 ? 120.795 165.333 126.837 1.00 30.23  ? 275 PRO B CD  1 
ATOM   5845  N N   . ILE B 1 276 ? 124.841 167.566 126.108 1.00 33.36  ? 276 ILE B N   1 
ATOM   5846  C CA  . ILE B 1 276 ? 126.130 167.918 126.693 1.00 33.36  ? 276 ILE B CA  1 
ATOM   5847  C C   . ILE B 1 276 ? 126.034 169.327 127.260 1.00 33.36  ? 276 ILE B C   1 
ATOM   5848  O O   . ILE B 1 276 ? 125.667 170.266 126.544 1.00 33.36  ? 276 ILE B O   1 
ATOM   5849  C CB  . ILE B 1 276 ? 127.262 167.821 125.655 1.00 33.36  ? 276 ILE B CB  1 
ATOM   5850  C CG1 . ILE B 1 276 ? 127.320 166.414 125.058 1.00 33.36  ? 276 ILE B CG1 1 
ATOM   5851  C CG2 . ILE B 1 276 ? 128.594 168.198 126.280 1.00 33.36  ? 276 ILE B CG2 1 
ATOM   5852  C CD1 . ILE B 1 276 ? 128.336 166.262 123.956 1.00 33.36  ? 276 ILE B CD1 1 
ATOM   5853  N N   . GLU B 1 277 ? 126.367 169.475 128.539 1.00 38.86  ? 277 GLU B N   1 
ATOM   5854  C CA  . GLU B 1 277 ? 126.341 170.764 129.214 1.00 38.86  ? 277 GLU B CA  1 
ATOM   5855  C C   . GLU B 1 277 ? 127.700 171.054 129.837 1.00 38.86  ? 277 GLU B C   1 
ATOM   5856  O O   . GLU B 1 277 ? 128.610 170.222 129.823 1.00 38.86  ? 277 GLU B O   1 
ATOM   5857  C CB  . GLU B 1 277 ? 125.251 170.810 130.291 1.00 38.86  ? 277 GLU B CB  1 
ATOM   5858  C CG  . GLU B 1 277 ? 125.488 169.858 131.449 1.00 38.86  ? 277 GLU B CG  1 
ATOM   5859  C CD  . GLU B 1 277 ? 124.364 169.884 132.464 1.00 38.86  ? 277 GLU B CD  1 
ATOM   5860  O OE1 . GLU B 1 277 ? 123.386 170.631 132.251 1.00 38.86  ? 277 GLU B OE1 1 
ATOM   5861  O OE2 . GLU B 1 277 ? 124.460 169.160 133.477 1.00 38.86  ? 277 GLU B OE2 1 
ATOM   5862  N N   . THR B 1 278 ? 127.824 172.256 130.396 1.00 40.30  ? 278 THR B N   1 
ATOM   5863  C CA  . THR B 1 278 ? 129.064 172.710 131.018 1.00 40.30  ? 278 THR B CA  1 
ATOM   5864  C C   . THR B 1 278 ? 129.075 172.284 132.483 1.00 40.30  ? 278 THR B C   1 
ATOM   5865  O O   . THR B 1 278 ? 128.350 172.850 133.307 1.00 40.30  ? 278 THR B O   1 
ATOM   5866  C CB  . THR B 1 278 ? 129.211 174.224 130.887 1.00 40.30  ? 278 THR B CB  1 
ATOM   5867  O OG1 . THR B 1 278 ? 129.195 174.588 129.502 1.00 40.30  ? 278 THR B OG1 1 
ATOM   5868  C CG2 . THR B 1 278 ? 130.518 174.687 131.510 1.00 40.30  ? 278 THR B CG2 1 
ATOM   5869  N N   . CYS B 1 279 ? 129.900 171.294 132.803 1.00 39.75  ? 279 CYS B N   1 
ATOM   5870  C CA  . CYS B 1 279 ? 130.036 170.771 134.159 1.00 39.75  ? 279 CYS B CA  1 
ATOM   5871  C C   . CYS B 1 279 ? 131.300 169.917 134.202 1.00 39.75  ? 279 CYS B C   1 
ATOM   5872  O O   . CYS B 1 279 ? 131.957 169.698 133.180 1.00 39.75  ? 279 CYS B O   1 
ATOM   5873  C CB  . CYS B 1 279 ? 128.795 169.982 134.583 1.00 39.75  ? 279 CYS B CB  1 
ATOM   5874  S SG  . CYS B 1 279 ? 128.265 168.710 133.413 1.00 39.75  ? 279 CYS B SG  1 
ATOM   5875  N N   . ILE B 1 280 ? 131.639 169.441 135.398 1.00 36.35  ? 280 ILE B N   1 
ATOM   5876  C CA  . ILE B 1 280 ? 132.840 168.645 135.626 1.00 36.35  ? 280 ILE B CA  1 
ATOM   5877  C C   . ILE B 1 280 ? 132.428 167.290 136.181 1.00 36.35  ? 280 ILE B C   1 
ATOM   5878  O O   . ILE B 1 280 ? 131.701 167.217 137.179 1.00 36.35  ? 280 ILE B O   1 
ATOM   5879  C CB  . ILE B 1 280 ? 133.817 169.349 136.585 1.00 36.35  ? 280 ILE B CB  1 
ATOM   5880  C CG1 . ILE B 1 280 ? 134.157 170.749 136.072 1.00 36.35  ? 280 ILE B CG1 1 
ATOM   5881  C CG2 . ILE B 1 280 ? 135.080 168.522 136.760 1.00 36.35  ? 280 ILE B CG2 1 
ATOM   5882  C CD1 . ILE B 1 280 ? 135.305 171.403 136.802 1.00 36.35  ? 280 ILE B CD1 1 
ATOM   5883  N N   . SER B 1 281 ? 132.895 166.222 135.538 1.00 33.77  ? 281 SER B N   1 
ATOM   5884  C CA  . SER B 1 281 ? 132.630 164.866 135.996 1.00 33.77  ? 281 SER B CA  1 
ATOM   5885  C C   . SER B 1 281 ? 133.654 163.932 135.371 1.00 33.77  ? 281 SER B C   1 
ATOM   5886  O O   . SER B 1 281 ? 133.984 164.068 134.191 1.00 33.77  ? 281 SER B O   1 
ATOM   5887  C CB  . SER B 1 281 ? 131.209 164.419 135.638 1.00 33.77  ? 281 SER B CB  1 
ATOM   5888  O OG  . SER B 1 281 ? 130.836 163.269 136.375 1.00 33.77  ? 281 SER B OG  1 
ATOM   5889  N N   . GLU B 1 282 ? 134.147 162.985 136.166 1.00 32.65  ? 282 GLU B N   1 
ATOM   5890  C CA  . GLU B 1 282 ? 135.182 162.062 135.719 1.00 32.65  ? 282 GLU B CA  1 
ATOM   5891  C C   . GLU B 1 282 ? 134.630 160.791 135.088 1.00 32.65  ? 282 GLU B C   1 
ATOM   5892  O O   . GLU B 1 282 ? 135.410 160.008 134.538 1.00 32.65  ? 282 GLU B O   1 
ATOM   5893  C CB  . GLU B 1 282 ? 136.093 161.686 136.892 1.00 32.65  ? 282 GLU B CB  1 
ATOM   5894  C CG  . GLU B 1 282 ? 136.819 162.864 137.514 1.00 32.65  ? 282 GLU B CG  1 
ATOM   5895  C CD  . GLU B 1 282 ? 138.187 163.091 136.906 1.00 32.65  ? 282 GLU B CD  1 
ATOM   5896  O OE1 . GLU B 1 282 ? 138.605 162.276 136.057 1.00 32.65  ? 282 GLU B OE1 1 
ATOM   5897  O OE2 . GLU B 1 282 ? 138.844 164.087 137.275 1.00 32.65  ? 282 GLU B OE2 1 
ATOM   5898  N N   . CYS B 1 283 ? 133.321 160.565 135.150 1.00 30.40  ? 283 CYS B N   1 
ATOM   5899  C CA  . CYS B 1 283 ? 132.711 159.359 134.612 1.00 30.40  ? 283 CYS B CA  1 
ATOM   5900  C C   . CYS B 1 283 ? 131.610 159.735 133.633 1.00 30.40  ? 283 CYS B C   1 
ATOM   5901  O O   . CYS B 1 283 ? 130.830 160.656 133.888 1.00 30.40  ? 283 CYS B O   1 
ATOM   5902  C CB  . CYS B 1 283 ? 132.140 158.480 135.730 1.00 30.40  ? 283 CYS B CB  1 
ATOM   5903  S SG  . CYS B 1 283 ? 131.403 156.937 135.160 1.00 30.40  ? 283 CYS B SG  1 
ATOM   5904  N N   . ILE B 1 284 ? 131.552 159.018 132.512 1.00 27.23  ? 284 ILE B N   1 
ATOM   5905  C CA  . ILE B 1 284 ? 130.546 159.242 131.481 1.00 27.23  ? 284 ILE B CA  1 
ATOM   5906  C C   . ILE B 1 284 ? 129.866 157.918 131.168 1.00 27.23  ? 284 ILE B C   1 
ATOM   5907  O O   . ILE B 1 284 ? 130.539 156.916 130.905 1.00 27.23  ? 284 ILE B O   1 
ATOM   5908  C CB  . ILE B 1 284 ? 131.158 159.850 130.204 1.00 27.23  ? 284 ILE B CB  1 
ATOM   5909  C CG1 . ILE B 1 284 ? 131.835 161.186 130.517 1.00 27.23  ? 284 ILE B CG1 1 
ATOM   5910  C CG2 . ILE B 1 284 ? 130.093 160.035 129.138 1.00 27.23  ? 284 ILE B CG2 1 
ATOM   5911  C CD1 . ILE B 1 284 ? 132.933 161.552 129.550 1.00 27.23  ? 284 ILE B CD1 1 
ATOM   5912  N N   . THR B 1 285 ? 128.540 157.916 131.199 1.00 26.26  ? 285 THR B N   1 
ATOM   5913  C CA  . THR B 1 285 ? 127.707 156.782 130.839 1.00 26.26  ? 285 THR B CA  1 
ATOM   5914  C C   . THR B 1 285 ? 126.717 157.207 129.762 1.00 26.26  ? 285 THR B C   1 
ATOM   5915  O O   . THR B 1 285 ? 126.470 158.404 129.577 1.00 26.26  ? 285 THR B O   1 
ATOM   5916  C CB  . THR B 1 285 ? 126.946 156.236 132.059 1.00 26.26  ? 285 THR B CB  1 
ATOM   5917  O OG1 . THR B 1 285 ? 125.893 157.139 132.417 1.00 26.26  ? 285 THR B OG1 1 
ATOM   5918  C CG2 . THR B 1 285 ? 127.878 156.058 133.246 1.00 26.26  ? 285 THR B CG2 1 
ATOM   5919  N N   . PRO B 1 286 ? 126.148 156.257 129.013 1.00 24.51  ? 286 PRO B N   1 
ATOM   5920  C CA  . PRO B 1 286 ? 125.105 156.624 128.041 1.00 24.51  ? 286 PRO B CA  1 
ATOM   5921  C C   . PRO B 1 286 ? 123.911 157.319 128.669 1.00 24.51  ? 286 PRO B C   1 
ATOM   5922  O O   . PRO B 1 286 ? 123.239 158.101 127.986 1.00 24.51  ? 286 PRO B O   1 
ATOM   5923  C CB  . PRO B 1 286 ? 124.711 155.276 127.426 1.00 24.51  ? 286 PRO B CB  1 
ATOM   5924  C CG  . PRO B 1 286 ? 125.922 154.440 127.570 1.00 24.51  ? 286 PRO B CG  1 
ATOM   5925  C CD  . PRO B 1 286 ? 126.564 154.852 128.863 1.00 24.51  ? 286 PRO B CD  1 
ATOM   5926  N N   . ASN B 1 287 ? 123.621 157.054 129.944 1.00 28.05  ? 287 ASN B N   1 
ATOM   5927  C CA  . ASN B 1 287 ? 122.574 157.781 130.651 1.00 28.05  ? 287 ASN B CA  1 
ATOM   5928  C C   . ASN B 1 287 ? 122.980 159.215 130.959 1.00 28.05  ? 287 ASN B C   1 
ATOM   5929  O O   . ASN B 1 287 ? 122.108 160.076 131.107 1.00 28.05  ? 287 ASN B O   1 
ATOM   5930  C CB  . ASN B 1 287 ? 122.233 157.065 131.956 1.00 28.05  ? 287 ASN B CB  1 
ATOM   5931  C CG  . ASN B 1 287 ? 121.903 155.604 131.754 1.00 28.05  ? 287 ASN B CG  1 
ATOM   5932  O OD1 . ASN B 1 287 ? 122.798 154.769 131.641 1.00 28.05  ? 287 ASN B OD1 1 
ATOM   5933  N ND2 . ASN B 1 287 ? 120.619 155.280 131.731 1.00 28.05  ? 287 ASN B ND2 1 
ATOM   5934  N N   . GLY B 1 288 ? 124.278 159.485 131.064 1.00 27.94  ? 288 GLY B N   1 
ATOM   5935  C CA  . GLY B 1 288 ? 124.832 160.758 131.460 1.00 27.94  ? 288 GLY B CA  1 
ATOM   5936  C C   . GLY B 1 288 ? 125.956 160.556 132.448 1.00 27.94  ? 288 GLY B C   1 
ATOM   5937  O O   . GLY B 1 288 ? 126.356 159.429 132.754 1.00 27.94  ? 288 GLY B O   1 
ATOM   5938  N N   . SER B 1 289 ? 126.478 161.663 132.964 1.00 29.61  ? 289 SER B N   1 
ATOM   5939  C CA  . SER B 1 289 ? 127.577 161.605 133.916 1.00 29.61  ? 289 SER B CA  1 
ATOM   5940  C C   . SER B 1 289 ? 127.065 161.279 135.315 1.00 29.61  ? 289 SER B C   1 
ATOM   5941  O O   . SER B 1 289 ? 125.982 161.711 135.720 1.00 29.61  ? 289 SER B O   1 
ATOM   5942  C CB  . SER B 1 289 ? 128.338 162.929 133.935 1.00 29.61  ? 289 SER B CB  1 
ATOM   5943  O OG  . SER B 1 289 ? 128.996 163.158 132.702 1.00 29.61  ? 289 SER B OG  1 
ATOM   5944  N N   . ILE B 1 290 ? 127.856 160.505 136.053 1.00 29.29  ? 290 ILE B N   1 
ATOM   5945  C CA  . ILE B 1 290 ? 127.514 160.133 137.425 1.00 29.29  ? 290 ILE B CA  1 
ATOM   5946  C C   . ILE B 1 290 ? 128.712 160.392 138.332 1.00 29.29  ? 290 ILE B C   1 
ATOM   5947  O O   . ILE B 1 290 ? 129.862 160.297 137.880 1.00 29.29  ? 290 ILE B O   1 
ATOM   5948  C CB  . ILE B 1 290 ? 127.068 158.664 137.517 1.00 29.29  ? 290 ILE B CB  1 
ATOM   5949  C CG1 . ILE B 1 290 ? 128.161 157.734 136.989 1.00 29.29  ? 290 ILE B CG1 1 
ATOM   5950  C CG2 . ILE B 1 290 ? 125.771 158.445 136.761 1.00 29.29  ? 290 ILE B CG2 1 
ATOM   5951  C CD1 . ILE B 1 290 ? 127.969 156.293 137.385 1.00 29.29  ? 290 ILE B CD1 1 
ATOM   5952  N N   . PRO B 1 291 ? 128.498 160.731 139.602 1.00 29.33  ? 291 PRO B N   1 
ATOM   5953  C CA  . PRO B 1 291 ? 129.628 160.870 140.526 1.00 29.33  ? 291 PRO B CA  1 
ATOM   5954  C C   . PRO B 1 291 ? 130.258 159.522 140.840 1.00 29.33  ? 291 PRO B C   1 
ATOM   5955  O O   . PRO B 1 291 ? 129.609 158.476 140.784 1.00 29.33  ? 291 PRO B O   1 
ATOM   5956  C CB  . PRO B 1 291 ? 128.998 161.495 141.776 1.00 29.33  ? 291 PRO B CB  1 
ATOM   5957  C CG  . PRO B 1 291 ? 127.541 161.212 141.662 1.00 29.33  ? 291 PRO B CG  1 
ATOM   5958  C CD  . PRO B 1 291 ? 127.226 161.163 140.204 1.00 29.33  ? 291 PRO B CD  1 
ATOM   5959  N N   . ASN B 1 292 ? 131.547 159.559 141.178 1.00 30.30  ? 292 ASN B N   1 
ATOM   5960  C CA  . ASN B 1 292 ? 132.314 158.353 141.468 1.00 30.30  ? 292 ASN B CA  1 
ATOM   5961  C C   . ASN B 1 292 ? 132.787 158.319 142.917 1.00 30.30  ? 292 ASN B C   1 
ATOM   5962  O O   . ASN B 1 292 ? 133.865 157.800 143.213 1.00 30.30  ? 292 ASN B O   1 
ATOM   5963  C CB  . ASN B 1 292 ? 133.501 158.223 140.514 1.00 30.30  ? 292 ASN B CB  1 
ATOM   5964  C CG  . ASN B 1 292 ? 134.381 159.456 140.503 1.00 30.30  ? 292 ASN B CG  1 
ATOM   5965  O OD1 . ASN B 1 292 ? 134.051 160.475 141.107 1.00 30.30  ? 292 ASN B OD1 1 
ATOM   5966  N ND2 . ASN B 1 292 ? 135.511 159.368 139.813 1.00 30.30  ? 292 ASN B ND2 1 
ATOM   5967  N N   . ASP B 1 293 ? 131.989 158.867 143.833 1.00 31.93  ? 293 ASP B N   1 
ATOM   5968  C CA  . ASP B 1 293 ? 132.327 158.834 145.249 1.00 31.93  ? 293 ASP B CA  1 
ATOM   5969  C C   . ASP B 1 293 ? 131.926 157.528 145.923 1.00 31.93  ? 293 ASP B C   1 
ATOM   5970  O O   . ASP B 1 293 ? 132.240 157.338 147.103 1.00 31.93  ? 293 ASP B O   1 
ATOM   5971  C CB  . ASP B 1 293 ? 131.672 160.013 145.974 1.00 31.93  ? 293 ASP B CB  1 
ATOM   5972  C CG  . ASP B 1 293 ? 130.173 159.848 146.123 1.00 31.93  ? 293 ASP B CG  1 
ATOM   5973  O OD1 . ASP B 1 293 ? 129.467 159.846 145.094 1.00 31.93  ? 293 ASP B OD1 1 
ATOM   5974  O OD2 . ASP B 1 293 ? 129.700 159.723 147.271 1.00 31.93  ? 293 ASP B OD2 1 
ATOM   5975  N N   . LYS B 1 294 ? 131.247 156.631 145.209 1.00 27.77  ? 294 LYS B N   1 
ATOM   5976  C CA  . LYS B 1 294 ? 130.852 155.326 145.708 1.00 27.77  ? 294 LYS B CA  1 
ATOM   5977  C C   . LYS B 1 294 ? 131.598 154.225 144.959 1.00 27.77  ? 294 LYS B C   1 
ATOM   5978  O O   . LYS B 1 294 ? 132.017 154.422 143.815 1.00 27.77  ? 294 LYS B O   1 
ATOM   5979  C CB  . LYS B 1 294 ? 129.341 155.112 145.560 1.00 27.77  ? 294 LYS B CB  1 
ATOM   5980  C CG  . LYS B 1 294 ? 128.508 155.913 146.542 1.00 27.77  ? 294 LYS B CG  1 
ATOM   5981  C CD  . LYS B 1 294 ? 127.042 155.915 146.154 1.00 27.77  ? 294 LYS B CD  1 
ATOM   5982  C CE  . LYS B 1 294 ? 126.321 157.115 146.736 1.00 27.77  ? 294 LYS B CE  1 
ATOM   5983  N NZ  . LYS B 1 294 ? 124.847 156.927 146.738 1.00 27.77  ? 294 LYS B NZ  1 
ATOM   5984  N N   . PRO B 1 295 ? 131.793 153.055 145.578 1.00 24.11  ? 295 PRO B N   1 
ATOM   5985  C CA  . PRO B 1 295 ? 132.545 151.989 144.899 1.00 24.11  ? 295 PRO B CA  1 
ATOM   5986  C C   . PRO B 1 295 ? 131.756 151.236 143.840 1.00 24.11  ? 295 PRO B C   1 
ATOM   5987  O O   . PRO B 1 295 ? 132.376 150.581 142.992 1.00 24.11  ? 295 PRO B O   1 
ATOM   5988  C CB  . PRO B 1 295 ? 132.943 151.057 146.051 1.00 24.11  ? 295 PRO B CB  1 
ATOM   5989  C CG  . PRO B 1 295 ? 131.890 151.269 147.075 1.00 24.11  ? 295 PRO B CG  1 
ATOM   5990  C CD  . PRO B 1 295 ? 131.496 152.714 146.980 1.00 24.11  ? 295 PRO B CD  1 
ATOM   5991  N N   . PHE B 1 296 ? 130.426 151.300 143.854 1.00 23.16  ? 296 PHE B N   1 
ATOM   5992  C CA  . PHE B 1 296 ? 129.599 150.542 142.928 1.00 23.16  ? 296 PHE B CA  1 
ATOM   5993  C C   . PHE B 1 296 ? 128.526 151.441 142.333 1.00 23.16  ? 296 PHE B C   1 
ATOM   5994  O O   . PHE B 1 296 ? 128.174 152.481 142.895 1.00 23.16  ? 296 PHE B O   1 
ATOM   5995  C CB  . PHE B 1 296 ? 128.946 149.334 143.615 1.00 23.16  ? 296 PHE B CB  1 
ATOM   5996  C CG  . PHE B 1 296 ? 129.903 148.506 144.420 1.00 23.16  ? 296 PHE B CG  1 
ATOM   5997  C CD1 . PHE B 1 296 ? 130.920 147.803 143.800 1.00 23.16  ? 296 PHE B CD1 1 
ATOM   5998  C CD2 . PHE B 1 296 ? 129.785 148.429 145.796 1.00 23.16  ? 296 PHE B CD2 1 
ATOM   5999  C CE1 . PHE B 1 296 ? 131.802 147.041 144.537 1.00 23.16  ? 296 PHE B CE1 1 
ATOM   6000  C CE2 . PHE B 1 296 ? 130.665 147.670 146.538 1.00 23.16  ? 296 PHE B CE2 1 
ATOM   6001  C CZ  . PHE B 1 296 ? 131.673 146.976 145.908 1.00 23.16  ? 296 PHE B CZ  1 
ATOM   6002  N N   . GLN B 1 297 ? 128.009 151.028 141.177 1.00 22.59  ? 297 GLN B N   1 
ATOM   6003  C CA  . GLN B 1 297 ? 126.951 151.761 140.498 1.00 22.59  ? 297 GLN B CA  1 
ATOM   6004  C C   . GLN B 1 297 ? 126.008 150.779 139.817 1.00 22.59  ? 297 GLN B C   1 
ATOM   6005  O O   . GLN B 1 297 ? 126.344 149.614 139.591 1.00 22.59  ? 297 GLN B O   1 
ATOM   6006  C CB  . GLN B 1 297 ? 127.513 152.765 139.479 1.00 22.59  ? 297 GLN B CB  1 
ATOM   6007  C CG  . GLN B 1 297 ? 128.483 152.177 138.469 1.00 22.59  ? 297 GLN B CG  1 
ATOM   6008  C CD  . GLN B 1 297 ? 127.855 151.965 137.108 1.00 22.59  ? 297 GLN B CD  1 
ATOM   6009  O OE1 . GLN B 1 297 ? 126.895 152.640 136.745 1.00 22.59  ? 297 GLN B OE1 1 
ATOM   6010  N NE2 . GLN B 1 297 ? 128.401 151.030 136.344 1.00 22.59  ? 297 GLN B NE2 1 
ATOM   6011  N N   . ASN B 1 298 ? 124.809 151.272 139.495 1.00 24.09  ? 298 ASN B N   1 
ATOM   6012  C CA  . ASN B 1 298 ? 123.750 150.460 138.907 1.00 24.09  ? 298 ASN B CA  1 
ATOM   6013  C C   . ASN B 1 298 ? 123.131 151.131 137.686 1.00 24.09  ? 298 ASN B C   1 
ATOM   6014  O O   . ASN B 1 298 ? 122.006 150.795 137.304 1.00 24.09  ? 298 ASN B O   1 
ATOM   6015  C CB  . ASN B 1 298 ? 122.670 150.161 139.951 1.00 24.09  ? 298 ASN B CB  1 
ATOM   6016  C CG  . ASN B 1 298 ? 121.846 148.939 139.609 1.00 24.09  ? 298 ASN B CG  1 
ATOM   6017  O OD1 . ASN B 1 298 ? 122.359 147.960 139.074 1.00 24.09  ? 298 ASN B OD1 1 
ATOM   6018  N ND2 . ASN B 1 298 ? 120.558 148.990 139.921 1.00 24.09  ? 298 ASN B ND2 1 
ATOM   6019  N N   . VAL B 1 299 ? 123.838 152.070 137.062 1.00 23.79  ? 299 VAL B N   1 
ATOM   6020  C CA  . VAL B 1 299 ? 123.275 152.869 135.980 1.00 23.79  ? 299 VAL B CA  1 
ATOM   6021  C C   . VAL B 1 299 ? 123.453 152.155 134.646 1.00 23.79  ? 299 VAL B C   1 
ATOM   6022  O O   . VAL B 1 299 ? 122.473 151.832 133.967 1.00 23.79  ? 299 VAL B O   1 
ATOM   6023  C CB  . VAL B 1 299 ? 123.915 154.268 135.946 1.00 23.79  ? 299 VAL B CB  1 
ATOM   6024  C CG1 . VAL B 1 299 ? 123.168 155.170 134.986 1.00 23.79  ? 299 VAL B CG1 1 
ATOM   6025  C CG2 . VAL B 1 299 ? 123.939 154.870 137.339 1.00 23.79  ? 299 VAL B CG2 1 
ATOM   6026  N N   . ASN B 1 300 ? 124.702 151.903 134.263 1.00 22.32  ? 300 ASN B N   1 
ATOM   6027  C CA  . ASN B 1 300 ? 124.999 151.300 132.972 1.00 22.32  ? 300 ASN B CA  1 
ATOM   6028  C C   . ASN B 1 300 ? 126.317 150.549 133.069 1.00 22.32  ? 300 ASN B C   1 
ATOM   6029  O O   . ASN B 1 300 ? 127.227 150.962 133.791 1.00 22.32  ? 300 ASN B O   1 
ATOM   6030  C CB  . ASN B 1 300 ? 125.071 152.360 131.867 1.00 22.32  ? 300 ASN B CB  1 
ATOM   6031  C CG  . ASN B 1 300 ? 124.524 151.867 130.545 1.00 22.32  ? 300 ASN B CG  1 
ATOM   6032  O OD1 . ASN B 1 300 ? 124.950 150.837 130.029 1.00 22.32  ? 300 ASN B OD1 1 
ATOM   6033  N ND2 . ASN B 1 300 ? 123.575 152.606 129.989 1.00 22.32  ? 300 ASN B ND2 1 
ATOM   6034  N N   . LYS B 1 301 ? 126.411 149.447 132.330 1.00 23.40  ? 301 LYS B N   1 
ATOM   6035  C CA  . LYS B 1 301 ? 127.653 148.692 132.239 1.00 23.40  ? 301 LYS B CA  1 
ATOM   6036  C C   . LYS B 1 301 ? 128.599 149.244 131.181 1.00 23.40  ? 301 LYS B C   1 
ATOM   6037  O O   . LYS B 1 301 ? 129.729 148.759 131.068 1.00 23.40  ? 301 LYS B O   1 
ATOM   6038  C CB  . LYS B 1 301 ? 127.362 147.214 131.960 1.00 23.40  ? 301 LYS B CB  1 
ATOM   6039  C CG  . LYS B 1 301 ? 126.635 146.946 130.661 1.00 23.40  ? 301 LYS B CG  1 
ATOM   6040  C CD  . LYS B 1 301 ? 126.174 145.500 130.589 1.00 23.40  ? 301 LYS B CD  1 
ATOM   6041  C CE  . LYS B 1 301 ? 125.720 145.132 129.186 1.00 23.40  ? 301 LYS B CE  1 
ATOM   6042  N NZ  . LYS B 1 301 ? 124.240 145.181 129.043 1.00 23.40  ? 301 LYS B NZ  1 
ATOM   6043  N N   . ILE B 1 302 ? 128.168 150.238 130.410 1.00 23.43  ? 302 ILE B N   1 
ATOM   6044  C CA  . ILE B 1 302 ? 129.028 150.960 129.482 1.00 23.43  ? 302 ILE B CA  1 
ATOM   6045  C C   . ILE B 1 302 ? 129.463 152.247 130.167 1.00 23.43  ? 302 ILE B C   1 
ATOM   6046  O O   . ILE B 1 302 ? 128.622 153.069 130.550 1.00 23.43  ? 302 ILE B O   1 
ATOM   6047  C CB  . ILE B 1 302 ? 128.306 151.253 128.157 1.00 23.43  ? 302 ILE B CB  1 
ATOM   6048  C CG1 . ILE B 1 302 ? 127.961 149.950 127.435 1.00 23.43  ? 302 ILE B CG1 1 
ATOM   6049  C CG2 . ILE B 1 302 ? 129.154 152.150 127.272 1.00 23.43  ? 302 ILE B CG2 1 
ATOM   6050  C CD1 . ILE B 1 302 ? 126.759 150.056 126.527 1.00 23.43  ? 302 ILE B CD1 1 
ATOM   6051  N N   . THR B 1 303 ? 130.773 152.427 130.328 1.00 27.02  ? 303 THR B N   1 
ATOM   6052  C CA  . THR B 1 303 ? 131.313 153.556 131.071 1.00 27.02  ? 303 THR B CA  1 
ATOM   6053  C C   . THR B 1 303 ? 132.610 154.023 130.426 1.00 27.02  ? 303 THR B C   1 
ATOM   6054  O O   . THR B 1 303 ? 133.262 153.285 129.684 1.00 27.02  ? 303 THR B O   1 
ATOM   6055  C CB  . THR B 1 303 ? 131.568 153.198 132.544 1.00 27.02  ? 303 THR B CB  1 
ATOM   6056  O OG1 . THR B 1 303 ? 132.157 151.894 132.627 1.00 27.02  ? 303 THR B OG1 1 
ATOM   6057  C CG2 . THR B 1 303 ? 130.273 153.216 133.341 1.00 27.02  ? 303 THR B CG2 1 
ATOM   6058  N N   . TYR B 1 304 ? 132.977 155.269 130.720 1.00 25.76  ? 304 TYR B N   1 
ATOM   6059  C CA  . TYR B 1 304 ? 134.225 155.852 130.245 1.00 25.76  ? 304 TYR B CA  1 
ATOM   6060  C C   . TYR B 1 304 ? 134.808 156.742 131.332 1.00 25.76  ? 304 TYR B C   1 
ATOM   6061  O O   . TYR B 1 304 ? 134.151 157.685 131.780 1.00 25.76  ? 304 TYR B O   1 
ATOM   6062  C CB  . TYR B 1 304 ? 134.013 156.661 128.960 1.00 25.76  ? 304 TYR B CB  1 
ATOM   6063  C CG  . TYR B 1 304 ? 135.283 157.273 128.412 1.00 25.76  ? 304 TYR B CG  1 
ATOM   6064  C CD1 . TYR B 1 304 ? 136.146 156.532 127.618 1.00 25.76  ? 304 TYR B CD1 1 
ATOM   6065  C CD2 . TYR B 1 304 ? 135.620 158.590 128.694 1.00 25.76  ? 304 TYR B CD2 1 
ATOM   6066  C CE1 . TYR B 1 304 ? 137.307 157.084 127.120 1.00 25.76  ? 304 TYR B CE1 1 
ATOM   6067  C CE2 . TYR B 1 304 ? 136.780 159.150 128.202 1.00 25.76  ? 304 TYR B CE2 1 
ATOM   6068  C CZ  . TYR B 1 304 ? 137.619 158.392 127.416 1.00 25.76  ? 304 TYR B CZ  1 
ATOM   6069  O OH  . TYR B 1 304 ? 138.776 158.945 126.920 1.00 25.76  ? 304 TYR B OH  1 
ATOM   6070  N N   . GLY B 1 305 ? 136.036 156.444 131.747 1.00 28.64  ? 305 GLY B N   1 
ATOM   6071  C CA  . GLY B 1 305 ? 136.709 157.247 132.749 1.00 28.64  ? 305 GLY B CA  1 
ATOM   6072  C C   . GLY B 1 305 ? 136.891 156.528 134.068 1.00 28.64  ? 305 GLY B C   1 
ATOM   6073  O O   . GLY B 1 305 ? 136.972 155.297 134.105 1.00 28.64  ? 305 GLY B O   1 
ATOM   6074  N N   . ALA B 1 306 ? 136.960 157.285 135.160 1.00 31.18  ? 306 ALA B N   1 
ATOM   6075  C CA  . ALA B 1 306 ? 137.071 156.716 136.502 1.00 31.18  ? 306 ALA B CA  1 
ATOM   6076  C C   . ALA B 1 306 ? 135.660 156.513 137.036 1.00 31.18  ? 306 ALA B C   1 
ATOM   6077  O O   . ALA B 1 306 ? 135.018 157.456 137.505 1.00 31.18  ? 306 ALA B O   1 
ATOM   6078  C CB  . ALA B 1 306 ? 137.893 157.623 137.410 1.00 31.18  ? 306 ALA B CB  1 
ATOM   6079  N N   . CYS B 1 307 ? 135.178 155.277 136.976 1.00 31.83  ? 307 CYS B N   1 
ATOM   6080  C CA  . CYS B 1 307 ? 133.794 154.974 137.292 1.00 31.83  ? 307 CYS B CA  1 
ATOM   6081  C C   . CYS B 1 307 ? 133.711 153.869 138.333 1.00 31.83  ? 307 CYS B C   1 
ATOM   6082  O O   . CYS B 1 307 ? 134.615 153.035 138.436 1.00 31.83  ? 307 CYS B O   1 
ATOM   6083  C CB  . CYS B 1 307 ? 133.028 154.541 136.032 1.00 31.83  ? 307 CYS B CB  1 
ATOM   6084  S SG  . CYS B 1 307 ? 132.998 155.766 134.711 1.00 31.83  ? 307 CYS B SG  1 
ATOM   6085  N N   . PRO B 1 308 ? 132.641 153.846 139.122 1.00 26.59  ? 308 PRO B N   1 
ATOM   6086  C CA  . PRO B 1 308 ? 132.418 152.718 140.030 1.00 26.59  ? 308 PRO B CA  1 
ATOM   6087  C C   . PRO B 1 308 ? 132.097 151.447 139.259 1.00 26.59  ? 308 PRO B C   1 
ATOM   6088  O O   . PRO B 1 308 ? 131.645 151.475 138.113 1.00 26.59  ? 308 PRO B O   1 
ATOM   6089  C CB  . PRO B 1 308 ? 131.223 153.167 140.879 1.00 26.59  ? 308 PRO B CB  1 
ATOM   6090  C CG  . PRO B 1 308 ? 131.119 154.641 140.678 1.00 26.59  ? 308 PRO B CG  1 
ATOM   6091  C CD  . PRO B 1 308 ? 131.652 154.919 139.314 1.00 26.59  ? 308 PRO B CD  1 
ATOM   6092  N N   . LYS B 1 309 ? 132.351 150.315 139.908 1.00 23.33  ? 309 LYS B N   1 
ATOM   6093  C CA  . LYS B 1 309 ? 132.091 149.024 139.288 1.00 23.33  ? 309 LYS B CA  1 
ATOM   6094  C C   . LYS B 1 309 ? 130.593 148.772 139.166 1.00 23.33  ? 309 LYS B C   1 
ATOM   6095  O O   . LYS B 1 309 ? 129.791 149.248 139.972 1.00 23.33  ? 309 LYS B O   1 
ATOM   6096  C CB  . LYS B 1 309 ? 132.751 147.907 140.092 1.00 23.33  ? 309 LYS B CB  1 
ATOM   6097  C CG  . LYS B 1 309 ? 134.248 148.076 140.232 1.00 23.33  ? 309 LYS B CG  1 
ATOM   6098  C CD  . LYS B 1 309 ? 134.880 146.897 140.933 1.00 23.33  ? 309 LYS B CD  1 
ATOM   6099  C CE  . LYS B 1 309 ? 136.360 147.135 141.153 1.00 23.33  ? 309 LYS B CE  1 
ATOM   6100  N NZ  . LYS B 1 309 ? 136.599 148.167 142.195 1.00 23.33  ? 309 LYS B NZ  1 
ATOM   6101  N N   . TYR B 1 310 ? 130.218 148.012 138.141 1.00 21.10  ? 310 TYR B N   1 
ATOM   6102  C CA  . TYR B 1 310 ? 128.817 147.736 137.860 1.00 21.10  ? 310 TYR B CA  1 
ATOM   6103  C C   . TYR B 1 310 ? 128.378 146.464 138.573 1.00 21.10  ? 310 TYR B C   1 
ATOM   6104  O O   . TYR B 1 310 ? 129.018 145.416 138.442 1.00 21.10  ? 310 TYR B O   1 
ATOM   6105  C CB  . TYR B 1 310 ? 128.579 147.604 136.355 1.00 21.10  ? 310 TYR B CB  1 
ATOM   6106  C CG  . TYR B 1 310 ? 127.128 147.386 135.999 1.00 21.10  ? 310 TYR B CG  1 
ATOM   6107  C CD1 . TYR B 1 310 ? 126.215 148.426 136.068 1.00 21.10  ? 310 TYR B CD1 1 
ATOM   6108  C CD2 . TYR B 1 310 ? 126.669 146.137 135.605 1.00 21.10  ? 310 TYR B CD2 1 
ATOM   6109  C CE1 . TYR B 1 310 ? 124.889 148.233 135.751 1.00 21.10  ? 310 TYR B CE1 1 
ATOM   6110  C CE2 . TYR B 1 310 ? 125.342 145.935 135.287 1.00 21.10  ? 310 TYR B CE2 1 
ATOM   6111  C CZ  . TYR B 1 310 ? 124.457 146.987 135.362 1.00 21.10  ? 310 TYR B CZ  1 
ATOM   6112  O OH  . TYR B 1 310 ? 123.133 146.795 135.046 1.00 21.10  ? 310 TYR B OH  1 
ATOM   6113  N N   . VAL B 1 311 ? 127.281 146.561 139.324 1.00 21.56  ? 311 VAL B N   1 
ATOM   6114  C CA  . VAL B 1 311 ? 126.712 145.435 140.048 1.00 21.56  ? 311 VAL B CA  1 
ATOM   6115  C C   . VAL B 1 311 ? 125.224 145.367 139.740 1.00 21.56  ? 311 VAL B C   1 
ATOM   6116  O O   . VAL B 1 311 ? 124.607 146.346 139.318 1.00 21.56  ? 311 VAL B O   1 
ATOM   6117  C CB  . VAL B 1 311 ? 126.945 145.537 141.572 1.00 21.56  ? 311 VAL B CB  1 
ATOM   6118  C CG1 . VAL B 1 311 ? 128.418 145.361 141.899 1.00 21.56  ? 311 VAL B CG1 1 
ATOM   6119  C CG2 . VAL B 1 311 ? 126.433 146.866 142.100 1.00 21.56  ? 311 VAL B CG2 1 
ATOM   6120  N N   . LYS B 1 312 ? 124.649 144.182 139.951 1.00 24.47  ? 312 LYS B N   1 
ATOM   6121  C CA  . LYS B 1 312 ? 123.230 143.977 139.689 1.00 24.47  ? 312 LYS B CA  1 
ATOM   6122  C C   . LYS B 1 312 ? 122.337 144.508 140.801 1.00 24.47  ? 312 LYS B C   1 
ATOM   6123  O O   . LYS B 1 312 ? 121.163 144.797 140.548 1.00 24.47  ? 312 LYS B O   1 
ATOM   6124  C CB  . LYS B 1 312 ? 122.940 142.491 139.477 1.00 24.47  ? 312 LYS B CB  1 
ATOM   6125  C CG  . LYS B 1 312 ? 123.471 141.933 138.174 1.00 24.47  ? 312 LYS B CG  1 
ATOM   6126  C CD  . LYS B 1 312 ? 123.054 140.487 137.997 1.00 24.47  ? 312 LYS B CD  1 
ATOM   6127  C CE  . LYS B 1 312 ? 123.846 139.574 138.915 1.00 24.47  ? 312 LYS B CE  1 
ATOM   6128  N NZ  . LYS B 1 312 ? 123.519 138.142 138.689 1.00 24.47  ? 312 LYS B NZ  1 
ATOM   6129  N N   . GLN B 1 313 ? 122.857 144.635 142.019 1.00 25.44  ? 313 GLN B N   1 
ATOM   6130  C CA  . GLN B 1 313 ? 122.059 145.143 143.124 1.00 25.44  ? 313 GLN B CA  1 
ATOM   6131  C C   . GLN B 1 313 ? 121.827 146.641 142.977 1.00 25.44  ? 313 GLN B C   1 
ATOM   6132  O O   . GLN B 1 313 ? 122.642 147.367 142.403 1.00 25.44  ? 313 GLN B O   1 
ATOM   6133  C CB  . GLN B 1 313 ? 122.745 144.849 144.457 1.00 25.44  ? 313 GLN B CB  1 
ATOM   6134  C CG  . GLN B 1 313 ? 123.054 143.382 144.683 1.00 25.44  ? 313 GLN B CG  1 
ATOM   6135  C CD  . GLN B 1 313 ? 124.522 143.063 144.506 1.00 25.44  ? 313 GLN B CD  1 
ATOM   6136  O OE1 . GLN B 1 313 ? 125.192 143.631 143.647 1.00 25.44  ? 313 GLN B OE1 1 
ATOM   6137  N NE2 . GLN B 1 313 ? 125.031 142.148 145.320 1.00 25.44  ? 313 GLN B NE2 1 
ATOM   6138  N N   . ASN B 1 314 ? 120.695 147.102 143.505 1.00 30.04  ? 314 ASN B N   1 
ATOM   6139  C CA  . ASN B 1 314 ? 120.351 148.516 143.476 1.00 30.04  ? 314 ASN B CA  1 
ATOM   6140  C C   . ASN B 1 314 ? 120.574 149.224 144.806 1.00 30.04  ? 314 ASN B C   1 
ATOM   6141  O O   . ASN B 1 314 ? 120.498 150.456 144.851 1.00 30.04  ? 314 ASN B O   1 
ATOM   6142  C CB  . ASN B 1 314 ? 118.894 148.698 143.018 1.00 30.04  ? 314 ASN B CB  1 
ATOM   6143  C CG  . ASN B 1 314 ? 117.887 148.080 143.975 1.00 30.04  ? 314 ASN B CG  1 
ATOM   6144  O OD1 . ASN B 1 314 ? 118.235 147.608 145.056 1.00 30.04  ? 314 ASN B OD1 1 
ATOM   6145  N ND2 . ASN B 1 314 ? 116.621 148.084 143.573 1.00 30.04  ? 314 ASN B ND2 1 
ATOM   6146  N N   . THR B 1 315 ? 120.850 148.486 145.879 1.00 30.09  ? 315 THR B N   1 
ATOM   6147  C CA  . THR B 1 315 ? 121.123 149.095 147.172 1.00 30.09  ? 315 THR B CA  1 
ATOM   6148  C C   . THR B 1 315 ? 122.019 148.173 147.989 1.00 30.09  ? 315 THR B C   1 
ATOM   6149  O O   . THR B 1 315 ? 121.858 146.950 147.962 1.00 30.09  ? 315 THR B O   1 
ATOM   6150  C CB  . THR B 1 315 ? 119.823 149.406 147.932 1.00 30.09  ? 315 THR B CB  1 
ATOM   6151  O OG1 . THR B 1 315 ? 120.132 150.026 149.186 1.00 30.09  ? 315 THR B OG1 1 
ATOM   6152  C CG2 . THR B 1 315 ? 119.008 148.144 148.175 1.00 30.09  ? 315 THR B CG2 1 
ATOM   6153  N N   . LEU B 1 316 ? 122.975 148.774 148.697 1.00 29.95  ? 316 LEU B N   1 
ATOM   6154  C CA  . LEU B 1 316 ? 123.879 148.042 149.583 1.00 29.95  ? 316 LEU B CA  1 
ATOM   6155  C C   . LEU B 1 316 ? 124.255 148.985 150.716 1.00 29.95  ? 316 LEU B C   1 
ATOM   6156  O O   . LEU B 1 316 ? 124.916 150.000 150.480 1.00 29.95  ? 316 LEU B O   1 
ATOM   6157  C CB  . LEU B 1 316 ? 125.124 147.558 148.842 1.00 29.95  ? 316 LEU B CB  1 
ATOM   6158  C CG  . LEU B 1 316 ? 125.027 146.319 147.949 1.00 29.95  ? 316 LEU B CG  1 
ATOM   6159  C CD1 . LEU B 1 316 ? 126.250 146.218 147.053 1.00 29.95  ? 316 LEU B CD1 1 
ATOM   6160  C CD2 . LEU B 1 316 ? 124.864 145.056 148.776 1.00 29.95  ? 316 LEU B CD2 1 
ATOM   6161  N N   . LYS B 1 317 ? 123.846 148.653 151.936 1.00 33.75  ? 317 LYS B N   1 
ATOM   6162  C CA  . LYS B 1 317 ? 124.025 149.527 153.088 1.00 33.75  ? 317 LYS B CA  1 
ATOM   6163  C C   . LYS B 1 317 ? 125.189 149.039 153.940 1.00 33.75  ? 317 LYS B C   1 
ATOM   6164  O O   . LYS B 1 317 ? 125.222 147.873 154.344 1.00 33.75  ? 317 LYS B O   1 
ATOM   6165  C CB  . LYS B 1 317 ? 122.749 149.586 153.927 1.00 33.75  ? 317 LYS B CB  1 
ATOM   6166  C CG  . LYS B 1 317 ? 121.506 149.972 153.147 1.00 33.75  ? 317 LYS B CG  1 
ATOM   6167  C CD  . LYS B 1 317 ? 121.561 151.419 152.695 1.00 33.75  ? 317 LYS B CD  1 
ATOM   6168  C CE  . LYS B 1 317 ? 121.363 152.365 153.863 1.00 33.75  ? 317 LYS B CE  1 
ATOM   6169  N NZ  . LYS B 1 317 ? 121.394 153.789 153.435 1.00 33.75  ? 317 LYS B NZ  1 
ATOM   6170  N N   . LEU B 1 318 ? 126.133 149.935 154.214 1.00 34.64  ? 318 LEU B N   1 
ATOM   6171  C CA  . LEU B 1 318 ? 127.291 149.648 155.051 1.00 34.64  ? 318 LEU B CA  1 
ATOM   6172  C C   . LEU B 1 318 ? 127.092 150.318 156.403 1.00 34.64  ? 318 LEU B C   1 
ATOM   6173  O O   . LEU B 1 318 ? 126.940 151.542 156.474 1.00 34.64  ? 318 LEU B O   1 
ATOM   6174  C CB  . LEU B 1 318 ? 128.577 150.140 154.387 1.00 34.64  ? 318 LEU B CB  1 
ATOM   6175  C CG  . LEU B 1 318 ? 129.901 149.850 155.095 1.00 34.64  ? 318 LEU B CG  1 
ATOM   6176  C CD1 . LEU B 1 318 ? 130.435 148.487 154.700 1.00 34.64  ? 318 LEU B CD1 1 
ATOM   6177  C CD2 . LEU B 1 318 ? 130.916 150.934 154.778 1.00 34.64  ? 318 LEU B CD2 1 
ATOM   6178  N N   . ALA B 1 319 ? 127.101 149.520 157.468 1.00 41.86  ? 319 ALA B N   1 
ATOM   6179  C CA  . ALA B 1 319 ? 126.847 150.045 158.802 1.00 41.86  ? 319 ALA B CA  1 
ATOM   6180  C C   . ALA B 1 319 ? 127.979 150.960 159.253 1.00 41.86  ? 319 ALA B C   1 
ATOM   6181  O O   . ALA B 1 319 ? 129.158 150.684 159.015 1.00 41.86  ? 319 ALA B O   1 
ATOM   6182  C CB  . ALA B 1 319 ? 126.671 148.901 159.799 1.00 41.86  ? 319 ALA B CB  1 
ATOM   6183  N N   . THR B 1 320 ? 127.611 152.058 159.911 1.00 47.11  ? 320 THR B N   1 
ATOM   6184  C CA  . THR B 1 320 ? 128.572 153.034 160.406 1.00 47.11  ? 320 THR B CA  1 
ATOM   6185  C C   . THR B 1 320 ? 128.627 153.109 161.924 1.00 47.11  ? 320 THR B C   1 
ATOM   6186  O O   . THR B 1 320 ? 129.711 153.291 162.480 1.00 47.11  ? 320 THR B O   1 
ATOM   6187  C CB  . THR B 1 320 ? 128.249 154.426 159.841 1.00 47.11  ? 320 THR B CB  1 
ATOM   6188  O OG1 . THR B 1 320 ? 128.435 154.421 158.421 1.00 47.11  ? 320 THR B OG1 1 
ATOM   6189  C CG2 . THR B 1 320 ? 129.153 155.489 160.446 1.00 47.11  ? 320 THR B CG2 1 
ATOM   6190  N N   . GLY B 1 321 ? 127.496 152.944 162.609 1.00 49.64  ? 321 GLY B N   1 
ATOM   6191  C CA  . GLY B 1 321 ? 127.445 152.986 164.049 1.00 49.64  ? 321 GLY B CA  1 
ATOM   6192  C C   . GLY B 1 321 ? 127.264 151.616 164.676 1.00 49.64  ? 321 GLY B C   1 
ATOM   6193  O O   . GLY B 1 321 ? 127.439 150.574 164.041 1.00 49.64  ? 321 GLY B O   1 
ATOM   6194  N N   . MET B 1 322 ? 126.907 151.635 165.957 1.00 51.83  ? 322 MET B N   1 
ATOM   6195  C CA  . MET B 1 322 ? 126.689 150.419 166.722 1.00 51.83  ? 322 MET B CA  1 
ATOM   6196  C C   . MET B 1 322 ? 125.233 149.974 166.607 1.00 51.83  ? 322 MET B C   1 
ATOM   6197  O O   . MET B 1 322 ? 124.438 150.540 165.853 1.00 51.83  ? 322 MET B O   1 
ATOM   6198  C CB  . MET B 1 322 ? 127.081 150.638 168.181 1.00 51.83  ? 322 MET B CB  1 
ATOM   6199  C CG  . MET B 1 322 ? 126.220 151.662 168.901 1.00 51.83  ? 322 MET B CG  1 
ATOM   6200  S SD  . MET B 1 322 ? 126.757 151.985 170.590 1.00 51.83  ? 322 MET B SD  1 
ATOM   6201  C CE  . MET B 1 322 ? 128.238 152.944 170.299 1.00 51.83  ? 322 MET B CE  1 
ATOM   6202  N N   . ARG B 1 323 ? 124.876 148.942 167.367 1.00 53.01  ? 323 ARG B N   1 
ATOM   6203  C CA  . ARG B 1 323 ? 123.493 148.491 167.413 1.00 53.01  ? 323 ARG B CA  1 
ATOM   6204  C C   . ARG B 1 323 ? 122.606 149.543 168.066 1.00 53.01  ? 323 ARG B C   1 
ATOM   6205  O O   . ARG B 1 323 ? 123.041 150.311 168.928 1.00 53.01  ? 323 ARG B O   1 
ATOM   6206  C CB  . ARG B 1 323 ? 123.375 147.177 168.185 1.00 53.01  ? 323 ARG B CB  1 
ATOM   6207  C CG  . ARG B 1 323 ? 124.019 145.980 167.517 1.00 53.01  ? 323 ARG B CG  1 
ATOM   6208  C CD  . ARG B 1 323 ? 123.838 144.738 168.375 1.00 53.01  ? 323 ARG B CD  1 
ATOM   6209  N NE  . ARG B 1 323 ? 124.460 143.559 167.785 1.00 53.01  ? 323 ARG B NE  1 
ATOM   6210  C CZ  . ARG B 1 323 ? 124.492 142.365 168.359 1.00 53.01  ? 323 ARG B CZ  1 
ATOM   6211  N NH1 . ARG B 1 323 ? 123.942 142.152 169.542 1.00 53.01  ? 323 ARG B NH1 1 
ATOM   6212  N NH2 . ARG B 1 323 ? 125.092 141.358 167.729 1.00 53.01  ? 323 ARG B NH2 1 
ATOM   6213  N N   . ASN B 1 324 ? 121.345 149.571 167.647 1.00 56.06  ? 324 ASN B N   1 
ATOM   6214  C CA  . ASN B 1 324 ? 120.351 150.474 168.210 1.00 56.06  ? 324 ASN B CA  1 
ATOM   6215  C C   . ASN B 1 324 ? 119.453 149.688 169.156 1.00 56.06  ? 324 ASN B C   1 
ATOM   6216  O O   . ASN B 1 324 ? 118.804 148.721 168.743 1.00 56.06  ? 324 ASN B O   1 
ATOM   6217  C CB  . ASN B 1 324 ? 119.528 151.134 167.104 1.00 56.06  ? 324 ASN B CB  1 
ATOM   6218  C CG  . ASN B 1 324 ? 119.101 152.542 167.458 1.00 56.06  ? 324 ASN B CG  1 
ATOM   6219  O OD1 . ASN B 1 324 ? 119.913 153.357 167.892 1.00 56.06  ? 324 ASN B OD1 1 
ATOM   6220  N ND2 . ASN B 1 324 ? 117.821 152.837 167.274 1.00 56.06  ? 324 ASN B ND2 1 
ATOM   6221  N N   . VAL B 1 325 ? 119.420 150.100 170.418 1.00 65.23  ? 325 VAL B N   1 
ATOM   6222  C CA  . VAL B 1 325 ? 118.618 149.458 171.449 1.00 65.23  ? 325 VAL B CA  1 
ATOM   6223  C C   . VAL B 1 325 ? 117.741 150.524 172.096 1.00 65.23  ? 325 VAL B C   1 
ATOM   6224  O O   . VAL B 1 325 ? 118.256 151.536 172.580 1.00 65.23  ? 325 VAL B O   1 
ATOM   6225  C CB  . VAL B 1 325 ? 119.484 148.754 172.508 1.00 65.23  ? 325 VAL B CB  1 
ATOM   6226  C CG1 . VAL B 1 325 ? 118.620 147.883 173.401 1.00 65.23  ? 325 VAL B CG1 1 
ATOM   6227  C CG2 . VAL B 1 325 ? 120.570 147.922 171.844 1.00 65.23  ? 325 VAL B CG2 1 
ATOM   6228  N N   . PRO B 1 326 ? 116.421 150.354 172.122 1.00 70.73  ? 326 PRO B N   1 
ATOM   6229  C CA  . PRO B 1 326 ? 115.561 151.358 172.758 1.00 70.73  ? 326 PRO B CA  1 
ATOM   6230  C C   . PRO B 1 326 ? 115.760 151.403 174.265 1.00 70.73  ? 326 PRO B C   1 
ATOM   6231  O O   . PRO B 1 326 ? 116.074 150.398 174.907 1.00 70.73  ? 326 PRO B O   1 
ATOM   6232  C CB  . PRO B 1 326 ? 114.145 150.894 172.399 1.00 70.73  ? 326 PRO B CB  1 
ATOM   6233  C CG  . PRO B 1 326 ? 114.277 149.441 172.102 1.00 70.73  ? 326 PRO B CG  1 
ATOM   6234  C CD  . PRO B 1 326 ? 115.656 149.229 171.558 1.00 70.73  ? 326 PRO B CD  1 
ATOM   6235  N N   . GLU B 1 327 ? 115.563 152.593 174.827 1.00 75.16  ? 327 GLU B N   1 
ATOM   6236  C CA  . GLU B 1 327 ? 115.693 152.788 176.264 1.00 75.16  ? 327 GLU B CA  1 
ATOM   6237  C C   . GLU B 1 327 ? 114.426 152.330 176.974 1.00 75.16  ? 327 GLU B C   1 
ATOM   6238  O O   . GLU B 1 327 ? 113.318 152.732 176.605 1.00 75.16  ? 327 GLU B O   1 
ATOM   6239  C CB  . GLU B 1 327 ? 115.973 154.256 176.582 1.00 75.16  ? 327 GLU B CB  1 
ATOM   6240  C CG  . GLU B 1 327 ? 116.142 154.547 178.067 1.00 75.16  ? 327 GLU B CG  1 
ATOM   6241  C CD  . GLU B 1 327 ? 117.047 155.734 178.333 1.00 75.16  ? 327 GLU B CD  1 
ATOM   6242  O OE1 . GLU B 1 327 ? 117.299 156.515 177.391 1.00 75.16  ? 327 GLU B OE1 1 
ATOM   6243  O OE2 . GLU B 1 327 ? 117.506 155.888 179.484 1.00 75.16  ? 327 GLU B OE2 1 
ATOM   6244  N N   . LYS B 1 328 ? 114.590 151.495 177.994 1.00 79.17  ? 328 LYS B N   1 
ATOM   6245  C CA  . LYS B 1 328 ? 113.455 151.001 178.765 1.00 79.17  ? 328 LYS B CA  1 
ATOM   6246  C C   . LYS B 1 328 ? 113.260 151.816 180.038 1.00 79.17  ? 328 LYS B C   1 
ATOM   6247  O O   . LYS B 1 328 ? 113.787 152.921 180.166 1.00 79.17  ? 328 LYS B O   1 
ATOM   6248  C CB  . LYS B 1 328 ? 113.641 149.523 179.112 1.00 79.17  ? 328 LYS B CB  1 
ATOM   6249  C CG  . LYS B 1 328 ? 114.801 149.247 180.052 1.00 79.17  ? 328 LYS B CG  1 
ATOM   6250  C CD  . LYS B 1 328 ? 114.785 147.806 180.533 1.00 79.17  ? 328 LYS B CD  1 
ATOM   6251  C CE  . LYS B 1 328 ? 115.046 146.839 179.392 1.00 79.17  ? 328 LYS B CE  1 
ATOM   6252  N NZ  . LYS B 1 328 ? 115.159 145.435 179.874 1.00 79.17  ? 328 LYS B NZ  1 
ATOM   6253  N N   . ALA B 1 336 ? 116.309 155.053 190.019 1.00 84.81  ? 336 ALA B N   1 
ATOM   6254  C CA  . ALA B 1 336 ? 117.045 153.832 189.716 1.00 84.81  ? 336 ALA B CA  1 
ATOM   6255  C C   . ALA B 1 336 ? 117.535 153.834 188.271 1.00 84.81  ? 336 ALA B C   1 
ATOM   6256  O O   . ALA B 1 336 ? 116.763 153.602 187.342 1.00 84.81  ? 336 ALA B O   1 
ATOM   6257  C CB  . ALA B 1 336 ? 116.178 152.610 189.981 1.00 84.81  ? 336 ALA B CB  1 
ATOM   6258  N N   . ILE B 1 337 ? 118.829 154.100 188.092 1.00 80.72  ? 337 ILE B N   1 
ATOM   6259  C CA  . ILE B 1 337 ? 119.416 154.127 186.760 1.00 80.72  ? 337 ILE B CA  1 
ATOM   6260  C C   . ILE B 1 337 ? 119.834 152.719 186.344 1.00 80.72  ? 337 ILE B C   1 
ATOM   6261  O O   . ILE B 1 337 ? 119.969 151.809 187.166 1.00 80.72  ? 337 ILE B O   1 
ATOM   6262  C CB  . ILE B 1 337 ? 120.601 155.107 186.705 1.00 80.72  ? 337 ILE B CB  1 
ATOM   6263  C CG1 . ILE B 1 337 ? 121.706 154.665 187.665 1.00 80.72  ? 337 ILE B CG1 1 
ATOM   6264  C CG2 . ILE B 1 337 ? 120.141 156.518 187.036 1.00 80.72  ? 337 ILE B CG2 1 
ATOM   6265  C CD1 . ILE B 1 337 ? 122.996 155.438 187.507 1.00 80.72  ? 337 ILE B CD1 1 
ATOM   6266  N N   . ALA B 1 338 ? 120.041 152.542 185.040 1.00 75.09  ? 338 ALA B N   1 
ATOM   6267  C CA  . ALA B 1 338 ? 120.329 151.238 184.462 1.00 75.09  ? 338 ALA B CA  1 
ATOM   6268  C C   . ALA B 1 338 ? 121.515 151.336 183.513 1.00 75.09  ? 338 ALA B C   1 
ATOM   6269  O O   . ALA B 1 338 ? 121.866 152.414 183.028 1.00 75.09  ? 338 ALA B O   1 
ATOM   6270  C CB  . ALA B 1 338 ? 119.111 150.669 183.722 1.00 75.09  ? 338 ALA B CB  1 
ATOM   6271  N N   . GLY B 1 339 ? 122.127 150.189 183.252 1.00 73.11  ? 339 GLY B N   1 
ATOM   6272  C CA  . GLY B 1 339 ? 123.326 150.083 182.446 1.00 73.11  ? 339 GLY B CA  1 
ATOM   6273  C C   . GLY B 1 339 ? 123.047 149.688 181.011 1.00 73.11  ? 339 GLY B C   1 
ATOM   6274  O O   . GLY B 1 339 ? 121.964 149.937 180.470 1.00 73.11  ? 339 GLY B O   1 
ATOM   6275  N N   . PHE B 1 340 ? 124.040 149.060 180.386 1.00 70.57  ? 340 PHE B N   1 
ATOM   6276  C CA  . PHE B 1 340 ? 124.001 148.743 178.964 1.00 70.57  ? 340 PHE B CA  1 
ATOM   6277  C C   . PHE B 1 340 ? 123.395 147.379 178.662 1.00 70.57  ? 340 PHE B C   1 
ATOM   6278  O O   . PHE B 1 340 ? 123.330 146.998 177.489 1.00 70.57  ? 340 PHE B O   1 
ATOM   6279  C CB  . PHE B 1 340 ? 125.413 148.815 178.372 1.00 70.57  ? 340 PHE B CB  1 
ATOM   6280  C CG  . PHE B 1 340 ? 126.336 147.733 178.863 1.00 70.57  ? 340 PHE B CG  1 
ATOM   6281  C CD1 . PHE B 1 340 ? 126.992 147.860 180.076 1.00 70.57  ? 340 PHE B CD1 1 
ATOM   6282  C CD2 . PHE B 1 340 ? 126.562 146.598 178.103 1.00 70.57  ? 340 PHE B CD2 1 
ATOM   6283  C CE1 . PHE B 1 340 ? 127.844 146.872 180.525 1.00 70.57  ? 340 PHE B CE1 1 
ATOM   6284  C CE2 . PHE B 1 340 ? 127.413 145.606 178.547 1.00 70.57  ? 340 PHE B CE2 1 
ATOM   6285  C CZ  . PHE B 1 340 ? 128.055 145.744 179.759 1.00 70.57  ? 340 PHE B CZ  1 
ATOM   6286  N N   . ILE B 1 341 ? 122.957 146.636 179.675 1.00 73.85  ? 341 ILE B N   1 
ATOM   6287  C CA  . ILE B 1 341 ? 122.389 145.306 179.464 1.00 73.85  ? 341 ILE B CA  1 
ATOM   6288  C C   . ILE B 1 341 ? 120.976 145.496 178.916 1.00 73.85  ? 341 ILE B C   1 
ATOM   6289  O O   . ILE B 1 341 ? 120.039 145.781 179.664 1.00 73.85  ? 341 ILE B O   1 
ATOM   6290  C CB  . ILE B 1 341 ? 122.395 144.468 180.744 1.00 73.85  ? 341 ILE B CB  1 
ATOM   6291  C CG1 . ILE B 1 341 ? 123.833 144.202 181.193 1.00 73.85  ? 341 ILE B CG1 1 
ATOM   6292  C CG2 . ILE B 1 341 ? 121.663 143.152 180.526 1.00 73.85  ? 341 ILE B CG2 1 
ATOM   6293  C CD1 . ILE B 1 341 ? 124.558 143.181 180.345 1.00 73.85  ? 341 ILE B CD1 1 
ATOM   6294  N N   . GLU B 1 342 ? 120.827 145.343 177.597 1.00 76.59  ? 342 GLU B N   1 
ATOM   6295  C CA  . GLU B 1 342 ? 119.538 145.472 176.915 1.00 76.59  ? 342 GLU B CA  1 
ATOM   6296  C C   . GLU B 1 342 ? 118.884 146.823 177.199 1.00 76.59  ? 342 GLU B C   1 
ATOM   6297  O O   . GLU B 1 342 ? 117.685 146.908 177.468 1.00 76.59  ? 342 GLU B O   1 
ATOM   6298  C CB  . GLU B 1 342 ? 118.597 144.325 177.292 1.00 76.59  ? 342 GLU B CB  1 
ATOM   6299  C CG  . GLU B 1 342 ? 119.153 142.940 177.004 1.00 76.59  ? 342 GLU B CG  1 
ATOM   6300  C CD  . GLU B 1 342 ? 119.316 142.671 175.521 1.00 76.59  ? 342 GLU B CD  1 
ATOM   6301  O OE1 . GLU B 1 342 ? 118.559 143.259 174.720 1.00 76.59  ? 342 GLU B OE1 1 
ATOM   6302  O OE2 . GLU B 1 342 ? 120.200 141.868 175.156 1.00 76.59  ? 342 GLU B OE2 1 
ATOM   6303  N N   . ASN B 1 343 ? 119.677 147.892 177.133 1.00 73.31  ? 343 ASN B N   1 
ATOM   6304  C CA  . ASN B 1 343 ? 119.169 149.225 177.431 1.00 73.31  ? 343 ASN B CA  1 
ATOM   6305  C C   . ASN B 1 343 ? 120.096 150.263 176.818 1.00 73.31  ? 343 ASN B C   1 
ATOM   6306  O O   . ASN B 1 343 ? 121.305 150.239 177.066 1.00 73.31  ? 343 ASN B O   1 
ATOM   6307  C CB  . ASN B 1 343 ? 119.051 149.439 178.946 1.00 73.31  ? 343 ASN B CB  1 
ATOM   6308  C CG  . ASN B 1 343 ? 118.620 150.846 179.305 1.00 73.31  ? 343 ASN B CG  1 
ATOM   6309  O OD1 . ASN B 1 343 ? 117.505 151.263 178.997 1.00 73.31  ? 343 ASN B OD1 1 
ATOM   6310  N ND2 . ASN B 1 343 ? 119.504 151.585 179.964 1.00 73.31  ? 343 ASN B ND2 1 
ATOM   6311  N N   . GLY B 1 344 ? 119.526 151.167 176.020 1.00 72.13  ? 344 GLY B N   1 
ATOM   6312  C CA  . GLY B 1 344 ? 120.266 152.274 175.457 1.00 72.13  ? 344 GLY B CA  1 
ATOM   6313  C C   . GLY B 1 344 ? 119.989 153.576 176.196 1.00 72.13  ? 344 GLY B C   1 
ATOM   6314  O O   . GLY B 1 344 ? 119.103 153.672 177.038 1.00 72.13  ? 344 GLY B O   1 
ATOM   6315  N N   . TRP B 1 345 ? 120.781 154.591 175.862 1.00 70.97  ? 345 TRP B N   1 
ATOM   6316  C CA  . TRP B 1 345 ? 120.676 155.914 176.477 1.00 70.97  ? 345 TRP B CA  1 
ATOM   6317  C C   . TRP B 1 345 ? 120.344 156.929 175.389 1.00 70.97  ? 345 TRP B C   1 
ATOM   6318  O O   . TRP B 1 345 ? 121.238 157.410 174.685 1.00 70.97  ? 345 TRP B O   1 
ATOM   6319  C CB  . TRP B 1 345 ? 121.965 156.285 177.206 1.00 70.97  ? 345 TRP B CB  1 
ATOM   6320  C CG  . TRP B 1 345 ? 122.204 155.499 178.458 1.00 70.97  ? 345 TRP B CG  1 
ATOM   6321  C CD1 . TRP B 1 345 ? 121.361 154.592 179.032 1.00 70.97  ? 345 TRP B CD1 1 
ATOM   6322  C CD2 . TRP B 1 345 ? 123.366 155.550 179.293 1.00 70.97  ? 345 TRP B CD2 1 
ATOM   6323  N NE1 . TRP B 1 345 ? 121.927 154.075 180.172 1.00 70.97  ? 345 TRP B NE1 1 
ATOM   6324  C CE2 . TRP B 1 345 ? 123.158 154.647 180.354 1.00 70.97  ? 345 TRP B CE2 1 
ATOM   6325  C CE3 . TRP B 1 345 ? 124.562 156.271 179.246 1.00 70.97  ? 345 TRP B CE3 1 
ATOM   6326  C CZ2 . TRP B 1 345 ? 124.100 154.448 181.359 1.00 70.97  ? 345 TRP B CZ2 1 
ATOM   6327  C CZ3 . TRP B 1 345 ? 125.496 156.071 180.244 1.00 70.97  ? 345 TRP B CZ3 1 
ATOM   6328  C CH2 . TRP B 1 345 ? 125.260 155.167 181.286 1.00 70.97  ? 345 TRP B CH2 1 
ATOM   6329  N N   . GLU B 1 346 ? 119.057 157.257 175.253 1.00 76.09  ? 346 GLU B N   1 
ATOM   6330  C CA  . GLU B 1 346 ? 118.642 158.251 174.270 1.00 76.09  ? 346 GLU B CA  1 
ATOM   6331  C C   . GLU B 1 346 ? 119.025 159.666 174.680 1.00 76.09  ? 346 GLU B C   1 
ATOM   6332  O O   . GLU B 1 346 ? 119.110 160.545 173.816 1.00 76.09  ? 346 GLU B O   1 
ATOM   6333  C CB  . GLU B 1 346 ? 117.132 158.169 174.040 1.00 76.09  ? 346 GLU B CB  1 
ATOM   6334  C CG  . GLU B 1 346 ? 116.698 156.965 173.222 1.00 76.09  ? 346 GLU B CG  1 
ATOM   6335  C CD  . GLU B 1 346 ? 115.199 156.907 173.015 1.00 76.09  ? 346 GLU B CD  1 
ATOM   6336  O OE1 . GLU B 1 346 ? 114.476 157.692 173.662 1.00 76.09  ? 346 GLU B OE1 1 
ATOM   6337  O OE2 . GLU B 1 346 ? 114.744 156.075 172.202 1.00 76.09  ? 346 GLU B OE2 1 
ATOM   6338  N N   . GLY B 1 347 ? 119.260 159.904 175.965 1.00 77.79  ? 347 GLY B N   1 
ATOM   6339  C CA  . GLY B 1 347 ? 119.640 161.207 176.462 1.00 77.79  ? 347 GLY B CA  1 
ATOM   6340  C C   . GLY B 1 347 ? 121.115 161.523 176.372 1.00 77.79  ? 347 GLY B C   1 
ATOM   6341  O O   . GLY B 1 347 ? 121.535 162.593 176.825 1.00 77.79  ? 347 GLY B O   1 
ATOM   6342  N N   . MET B 1 348 ? 121.919 160.629 175.804 1.00 74.43  ? 348 MET B N   1 
ATOM   6343  C CA  . MET B 1 348 ? 123.358 160.825 175.682 1.00 74.43  ? 348 MET B CA  1 
ATOM   6344  C C   . MET B 1 348 ? 123.666 161.326 174.276 1.00 74.43  ? 348 MET B C   1 
ATOM   6345  O O   . MET B 1 348 ? 123.444 160.612 173.293 1.00 74.43  ? 348 MET B O   1 
ATOM   6346  C CB  . MET B 1 348 ? 124.111 159.532 175.980 1.00 74.43  ? 348 MET B CB  1 
ATOM   6347  C CG  . MET B 1 348 ? 125.607 159.650 175.781 1.00 74.43  ? 348 MET B CG  1 
ATOM   6348  S SD  . MET B 1 348 ? 126.548 158.395 176.660 1.00 74.43  ? 348 MET B SD  1 
ATOM   6349  C CE  . MET B 1 348 ? 128.145 159.195 176.721 1.00 74.43  ? 348 MET B CE  1 
ATOM   6350  N N   . ILE B 1 349 ? 124.182 162.550 174.184 1.00 77.29  ? 349 ILE B N   1 
ATOM   6351  C CA  . ILE B 1 349 ? 124.497 163.165 172.900 1.00 77.29  ? 349 ILE B CA  1 
ATOM   6352  C C   . ILE B 1 349 ? 125.933 163.670 172.915 1.00 77.29  ? 349 ILE B C   1 
ATOM   6353  O O   . ILE B 1 349 ? 126.392 164.296 171.953 1.00 77.29  ? 349 ILE B O   1 
ATOM   6354  C CB  . ILE B 1 349 ? 123.518 164.308 172.575 1.00 77.29  ? 349 ILE B CB  1 
ATOM   6355  C CG1 . ILE B 1 349 ? 123.506 165.334 173.709 1.00 77.29  ? 349 ILE B CG1 1 
ATOM   6356  C CG2 . ILE B 1 349 ? 122.121 163.761 172.321 1.00 77.29  ? 349 ILE B CG2 1 
ATOM   6357  C CD1 . ILE B 1 349 ? 122.765 166.608 173.374 1.00 77.29  ? 349 ILE B CD1 1 
ATOM   6358  N N   . ASP B 1 350 ? 126.650 163.403 174.005 1.00 75.90  ? 350 ASP B N   1 
ATOM   6359  C CA  . ASP B 1 350 ? 128.021 163.868 174.164 1.00 75.90  ? 350 ASP B CA  1 
ATOM   6360  C C   . ASP B 1 350 ? 129.057 162.876 173.653 1.00 75.90  ? 350 ASP B C   1 
ATOM   6361  O O   . ASP B 1 350 ? 130.221 163.255 173.485 1.00 75.90  ? 350 ASP B O   1 
ATOM   6362  C CB  . ASP B 1 350 ? 128.304 164.179 175.640 1.00 75.90  ? 350 ASP B CB  1 
ATOM   6363  C CG  . ASP B 1 350 ? 129.349 165.262 175.816 1.00 75.90  ? 350 ASP B CG  1 
ATOM   6364  O OD1 . ASP B 1 350 ? 129.398 166.185 174.976 1.00 75.90  ? 350 ASP B OD1 1 
ATOM   6365  O OD2 . ASP B 1 350 ? 130.123 165.190 176.794 1.00 75.90  ? 350 ASP B OD2 1 
ATOM   6366  N N   . GLY B 1 351 ? 128.670 161.632 173.400 1.00 72.74  ? 351 GLY B N   1 
ATOM   6367  C CA  . GLY B 1 351 ? 129.624 160.645 172.937 1.00 72.74  ? 351 GLY B CA  1 
ATOM   6368  C C   . GLY B 1 351 ? 128.954 159.304 172.741 1.00 72.74  ? 351 GLY B C   1 
ATOM   6369  O O   . GLY B 1 351 ? 127.734 159.173 172.854 1.00 72.74  ? 351 GLY B O   1 
ATOM   6370  N N   . TRP B 1 352 ? 129.779 158.300 172.444 1.00 63.00  ? 352 TRP B N   1 
ATOM   6371  C CA  . TRP B 1 352 ? 129.287 156.948 172.212 1.00 63.00  ? 352 TRP B CA  1 
ATOM   6372  C C   . TRP B 1 352 ? 129.186 156.140 173.499 1.00 63.00  ? 352 TRP B C   1 
ATOM   6373  O O   . TRP B 1 352 ? 128.207 155.413 173.696 1.00 63.00  ? 352 TRP B O   1 
ATOM   6374  C CB  . TRP B 1 352 ? 130.191 156.220 171.213 1.00 63.00  ? 352 TRP B CB  1 
ATOM   6375  C CG  . TRP B 1 352 ? 130.055 156.705 169.798 1.00 63.00  ? 352 TRP B CG  1 
ATOM   6376  C CD1 . TRP B 1 352 ? 129.623 157.933 169.389 1.00 63.00  ? 352 TRP B CD1 1 
ATOM   6377  C CD2 . TRP B 1 352 ? 130.357 155.969 168.607 1.00 63.00  ? 352 TRP B CD2 1 
ATOM   6378  N NE1 . TRP B 1 352 ? 129.636 158.007 168.018 1.00 63.00  ? 352 TRP B NE1 1 
ATOM   6379  C CE2 . TRP B 1 352 ? 130.082 156.814 167.513 1.00 63.00  ? 352 TRP B CE2 1 
ATOM   6380  C CE3 . TRP B 1 352 ? 130.832 154.678 168.358 1.00 63.00  ? 352 TRP B CE3 1 
ATOM   6381  C CZ2 . TRP B 1 352 ? 130.267 156.410 166.193 1.00 63.00  ? 352 TRP B CZ2 1 
ATOM   6382  C CZ3 . TRP B 1 352 ? 131.014 154.279 167.047 1.00 63.00  ? 352 TRP B CZ3 1 
ATOM   6383  C CH2 . TRP B 1 352 ? 130.733 155.142 165.982 1.00 63.00  ? 352 TRP B CH2 1 
ATOM   6384  N N   . TYR B 1 353 ? 130.178 156.249 174.379 1.00 63.44  ? 353 TYR B N   1 
ATOM   6385  C CA  . TYR B 1 353 ? 130.192 155.533 175.645 1.00 63.44  ? 353 TYR B CA  1 
ATOM   6386  C C   . TYR B 1 353 ? 130.397 156.522 176.781 1.00 63.44  ? 353 TYR B C   1 
ATOM   6387  O O   . TYR B 1 353 ? 131.061 157.549 176.616 1.00 63.44  ? 353 TYR B O   1 
ATOM   6388  C CB  . TYR B 1 353 ? 131.295 154.465 175.674 1.00 63.44  ? 353 TYR B CB  1 
ATOM   6389  C CG  . TYR B 1 353 ? 131.355 153.608 174.430 1.00 63.44  ? 353 TYR B CG  1 
ATOM   6390  C CD1 . TYR B 1 353 ? 130.499 152.530 174.264 1.00 63.44  ? 353 TYR B CD1 1 
ATOM   6391  C CD2 . TYR B 1 353 ? 132.275 153.872 173.425 1.00 63.44  ? 353 TYR B CD2 1 
ATOM   6392  C CE1 . TYR B 1 353 ? 130.551 151.743 173.132 1.00 63.44  ? 353 TYR B CE1 1 
ATOM   6393  C CE2 . TYR B 1 353 ? 132.334 153.090 172.289 1.00 63.44  ? 353 TYR B CE2 1 
ATOM   6394  C CZ  . TYR B 1 353 ? 131.470 152.027 172.148 1.00 63.44  ? 353 TYR B CZ  1 
ATOM   6395  O OH  . TYR B 1 353 ? 131.525 151.245 171.019 1.00 63.44  ? 353 TYR B OH  1 
ATOM   6396  N N   . GLY B 1 354 ? 129.824 156.208 177.938 1.00 71.08  ? 354 GLY B N   1 
ATOM   6397  C CA  . GLY B 1 354 ? 129.926 157.115 179.066 1.00 71.08  ? 354 GLY B CA  1 
ATOM   6398  C C   . GLY B 1 354 ? 129.491 156.449 180.352 1.00 71.08  ? 354 GLY B C   1 
ATOM   6399  O O   . GLY B 1 354 ? 129.211 155.248 180.396 1.00 71.08  ? 354 GLY B O   1 
ATOM   6400  N N   . PHE B 1 355 ? 129.439 157.259 181.407 1.00 74.36  ? 355 PHE B N   1 
ATOM   6401  C CA  . PHE B 1 355 ? 129.094 156.806 182.745 1.00 74.36  ? 355 PHE B CA  1 
ATOM   6402  C C   . PHE B 1 355 ? 127.860 157.543 183.248 1.00 74.36  ? 355 PHE B C   1 
ATOM   6403  O O   . PHE B 1 355 ? 127.606 158.691 182.875 1.00 74.36  ? 355 PHE B O   1 
ATOM   6404  C CB  . PHE B 1 355 ? 130.246 157.034 183.735 1.00 74.36  ? 355 PHE B CB  1 
ATOM   6405  C CG  . PHE B 1 355 ? 131.533 156.363 183.348 1.00 74.36  ? 355 PHE B CG  1 
ATOM   6406  C CD1 . PHE B 1 355 ? 132.409 156.968 182.463 1.00 74.36  ? 355 PHE B CD1 1 
ATOM   6407  C CD2 . PHE B 1 355 ? 131.878 155.136 183.888 1.00 74.36  ? 355 PHE B CD2 1 
ATOM   6408  C CE1 . PHE B 1 355 ? 133.596 156.357 182.113 1.00 74.36  ? 355 PHE B CE1 1 
ATOM   6409  C CE2 . PHE B 1 355 ? 133.063 154.520 183.543 1.00 74.36  ? 355 PHE B CE2 1 
ATOM   6410  C CZ  . PHE B 1 355 ? 133.923 155.131 182.654 1.00 74.36  ? 355 PHE B CZ  1 
ATOM   6411  N N   . ARG B 1 356 ? 127.095 156.867 184.102 1.00 76.32  ? 356 ARG B N   1 
ATOM   6412  C CA  . ARG B 1 356 ? 126.000 157.478 184.844 1.00 76.32  ? 356 ARG B CA  1 
ATOM   6413  C C   . ARG B 1 356 ? 126.093 157.027 186.292 1.00 76.32  ? 356 ARG B C   1 
ATOM   6414  O O   . ARG B 1 356 ? 126.194 155.827 186.563 1.00 76.32  ? 356 ARG B O   1 
ATOM   6415  C CB  . ARG B 1 356 ? 124.635 157.101 184.261 1.00 76.32  ? 356 ARG B CB  1 
ATOM   6416  C CG  . ARG B 1 356 ? 124.121 158.051 183.196 1.00 76.32  ? 356 ARG B CG  1 
ATOM   6417  C CD  . ARG B 1 356 ? 122.688 157.716 182.822 1.00 76.32  ? 356 ARG B CD  1 
ATOM   6418  N NE  . ARG B 1 356 ? 122.244 158.432 181.633 1.00 76.32  ? 356 ARG B NE  1 
ATOM   6419  C CZ  . ARG B 1 356 ? 121.091 158.211 181.016 1.00 76.32  ? 356 ARG B CZ  1 
ATOM   6420  N NH1 . ARG B 1 356 ? 120.236 157.303 181.454 1.00 76.32  ? 356 ARG B NH1 1 
ATOM   6421  N NH2 . ARG B 1 356 ? 120.790 158.919 179.932 1.00 76.32  ? 356 ARG B NH2 1 
ATOM   6422  N N   . HIS B 1 357 ? 126.059 157.982 187.217 1.00 86.32  ? 357 HIS B N   1 
ATOM   6423  C CA  . HIS B 1 357 ? 126.186 157.683 188.635 1.00 86.32  ? 357 HIS B CA  1 
ATOM   6424  C C   . HIS B 1 357 ? 125.055 158.342 189.407 1.00 86.32  ? 357 HIS B C   1 
ATOM   6425  O O   . HIS B 1 357 ? 124.664 159.475 189.111 1.00 86.32  ? 357 HIS B O   1 
ATOM   6426  C CB  . HIS B 1 357 ? 127.543 158.149 189.188 1.00 86.32  ? 357 HIS B CB  1 
ATOM   6427  C CG  . HIS B 1 357 ? 127.632 159.625 189.422 1.00 86.32  ? 357 HIS B CG  1 
ATOM   6428  N ND1 . HIS B 1 357 ? 128.117 160.501 188.475 1.00 86.32  ? 357 HIS B ND1 1 
ATOM   6429  C CD2 . HIS B 1 357 ? 127.309 160.379 190.500 1.00 86.32  ? 357 HIS B CD2 1 
ATOM   6430  C CE1 . HIS B 1 357 ? 128.083 161.731 188.956 1.00 86.32  ? 357 HIS B CE1 1 
ATOM   6431  N NE2 . HIS B 1 357 ? 127.596 161.684 190.183 1.00 86.32  ? 357 HIS B NE2 1 
ATOM   6432  N N   . GLN B 1 358 ? 124.525 157.621 190.390 1.00 91.22  ? 358 GLN B N   1 
ATOM   6433  C CA  . GLN B 1 358 ? 123.538 158.154 191.317 1.00 91.22  ? 358 GLN B CA  1 
ATOM   6434  C C   . GLN B 1 358 ? 124.152 158.217 192.708 1.00 91.22  ? 358 GLN B C   1 
ATOM   6435  O O   . GLN B 1 358 ? 124.598 157.196 193.242 1.00 91.22  ? 358 GLN B O   1 
ATOM   6436  C CB  . GLN B 1 358 ? 122.271 157.297 191.334 1.00 91.22  ? 358 GLN B CB  1 
ATOM   6437  C CG  . GLN B 1 358 ? 121.170 157.855 192.218 1.00 91.22  ? 358 GLN B CG  1 
ATOM   6438  C CD  . GLN B 1 358 ? 119.906 157.023 192.173 1.00 91.22  ? 358 GLN B CD  1 
ATOM   6439  O OE1 . GLN B 1 358 ? 119.852 155.992 191.503 1.00 91.22  ? 358 GLN B OE1 1 
ATOM   6440  N NE2 . GLN B 1 358 ? 118.881 157.466 192.891 1.00 91.22  ? 358 GLN B NE2 1 
ATOM   6441  N N   . ASN B 1 359 ? 124.171 159.412 193.288 1.00 99.01  ? 359 ASN B N   1 
ATOM   6442  C CA  . ASN B 1 359 ? 124.783 159.651 194.586 1.00 99.01  ? 359 ASN B CA  1 
ATOM   6443  C C   . ASN B 1 359 ? 123.773 160.343 195.492 1.00 99.01  ? 359 ASN B C   1 
ATOM   6444  O O   . ASN B 1 359 ? 122.663 160.687 195.075 1.00 99.01  ? 359 ASN B O   1 
ATOM   6445  C CB  . ASN B 1 359 ? 126.062 160.487 194.444 1.00 99.01  ? 359 ASN B CB  1 
ATOM   6446  C CG  . ASN B 1 359 ? 127.061 160.217 195.549 1.00 99.01  ? 359 ASN B CG  1 
ATOM   6447  O OD1 . ASN B 1 359 ? 126.885 159.300 196.350 1.00 99.01  ? 359 ASN B OD1 1 
ATOM   6448  N ND2 . ASN B 1 359 ? 128.121 161.014 195.596 1.00 99.01  ? 359 ASN B ND2 1 
ATOM   6449  N N   . SER B 1 360 ? 124.166 160.540 196.753 1.00 102.43 ? 360 SER B N   1 
ATOM   6450  C CA  . SER B 1 360 ? 123.318 161.278 197.682 1.00 102.43 ? 360 SER B CA  1 
ATOM   6451  C C   . SER B 1 360 ? 123.132 162.719 197.224 1.00 102.43 ? 360 SER B C   1 
ATOM   6452  O O   . SER B 1 360 ? 122.062 163.308 197.416 1.00 102.43 ? 360 SER B O   1 
ATOM   6453  C CB  . SER B 1 360 ? 123.916 161.233 199.087 1.00 102.43 ? 360 SER B CB  1 
ATOM   6454  O OG  . SER B 1 360 ? 125.187 161.858 199.118 1.00 102.43 ? 360 SER B OG  1 
ATOM   6455  N N   . GLU B 1 361 ? 124.168 163.301 196.618 1.00 102.33 ? 361 GLU B N   1 
ATOM   6456  C CA  . GLU B 1 361 ? 124.070 164.672 196.130 1.00 102.33 ? 361 GLU B CA  1 
ATOM   6457  C C   . GLU B 1 361 ? 123.161 164.764 194.910 1.00 102.33 ? 361 GLU B C   1 
ATOM   6458  O O   . GLU B 1 361 ? 122.470 165.772 194.720 1.00 102.33 ? 361 GLU B O   1 
ATOM   6459  C CB  . GLU B 1 361 ? 125.465 165.204 195.809 1.00 102.33 ? 361 GLU B CB  1 
ATOM   6460  C CG  . GLU B 1 361 ? 126.412 165.180 196.997 1.00 102.33 ? 361 GLU B CG  1 
ATOM   6461  C CD  . GLU B 1 361 ? 127.834 165.519 196.610 1.00 102.33 ? 361 GLU B CD  1 
ATOM   6462  O OE1 . GLU B 1 361 ? 128.099 165.639 195.398 1.00 102.33 ? 361 GLU B OE1 1 
ATOM   6463  O OE2 . GLU B 1 361 ? 128.685 165.664 197.512 1.00 102.33 ? 361 GLU B OE2 1 
ATOM   6464  N N   . GLY B 1 362 ? 123.150 163.738 194.078 1.00 98.63  ? 362 GLY B N   1 
ATOM   6465  C CA  . GLY B 1 362 ? 122.282 163.715 192.917 1.00 98.63  ? 362 GLY B CA  1 
ATOM   6466  C C   . GLY B 1 362 ? 122.876 162.858 191.818 1.00 98.63  ? 362 GLY B C   1 
ATOM   6467  O O   . GLY B 1 362 ? 124.011 162.396 191.898 1.00 98.63  ? 362 GLY B O   1 
ATOM   6468  N N   . THR B 1 363 ? 122.070 162.656 190.780 1.00 93.33  ? 363 THR B N   1 
ATOM   6469  C CA  . THR B 1 363 ? 122.509 161.883 189.628 1.00 93.33  ? 363 THR B CA  1 
ATOM   6470  C C   . THR B 1 363 ? 123.462 162.701 188.764 1.00 93.33  ? 363 THR B C   1 
ATOM   6471  O O   . THR B 1 363 ? 123.466 163.934 188.795 1.00 93.33  ? 363 THR B O   1 
ATOM   6472  C CB  . THR B 1 363 ? 121.311 161.430 188.793 1.00 93.33  ? 363 THR B CB  1 
ATOM   6473  O OG1 . THR B 1 363 ? 120.766 162.551 188.087 1.00 93.33  ? 363 THR B OG1 1 
ATOM   6474  C CG2 . THR B 1 363 ? 120.235 160.830 189.686 1.00 93.33  ? 363 THR B CG2 1 
ATOM   6475  N N   . GLY B 1 364 ? 124.278 161.997 187.985 1.00 86.67  ? 364 GLY B N   1 
ATOM   6476  C CA  . GLY B 1 364 ? 125.226 162.649 187.101 1.00 86.67  ? 364 GLY B CA  1 
ATOM   6477  C C   . GLY B 1 364 ? 125.532 161.777 185.904 1.00 86.67  ? 364 GLY B C   1 
ATOM   6478  O O   . GLY B 1 364 ? 125.338 160.558 185.929 1.00 86.67  ? 364 GLY B O   1 
ATOM   6479  N N   . GLN B 1 365 ? 126.015 162.424 184.846 1.00 77.78  ? 365 GLN B N   1 
ATOM   6480  C CA  . GLN B 1 365 ? 126.347 161.743 183.604 1.00 77.78  ? 365 GLN B CA  1 
ATOM   6481  C C   . GLN B 1 365 ? 127.617 162.346 183.023 1.00 77.78  ? 365 GLN B C   1 
ATOM   6482  O O   . GLN B 1 365 ? 127.890 163.537 183.190 1.00 77.78  ? 365 GLN B O   1 
ATOM   6483  C CB  . GLN B 1 365 ? 125.197 161.841 182.589 1.00 77.78  ? 365 GLN B CB  1 
ATOM   6484  C CG  . GLN B 1 365 ? 125.415 161.048 181.310 1.00 77.78  ? 365 GLN B CG  1 
ATOM   6485  C CD  . GLN B 1 365 ? 124.172 160.977 180.447 1.00 77.78  ? 365 GLN B CD  1 
ATOM   6486  O OE1 . GLN B 1 365 ? 123.060 161.220 180.916 1.00 77.78  ? 365 GLN B OE1 1 
ATOM   6487  N NE2 . GLN B 1 365 ? 124.355 160.647 179.175 1.00 77.78  ? 365 GLN B NE2 1 
ATOM   6488  N N   . ALA B 1 366 ? 128.391 161.508 182.338 1.00 77.01  ? 366 ALA B N   1 
ATOM   6489  C CA  . ALA B 1 366 ? 129.603 161.949 181.664 1.00 77.01  ? 366 ALA B CA  1 
ATOM   6490  C C   . ALA B 1 366 ? 129.836 161.057 180.454 1.00 77.01  ? 366 ALA B C   1 
ATOM   6491  O O   . ALA B 1 366 ? 129.084 160.114 180.197 1.00 77.01  ? 366 ALA B O   1 
ATOM   6492  C CB  . ALA B 1 366 ? 130.812 161.927 182.603 1.00 77.01  ? 366 ALA B CB  1 
ATOM   6493  N N   . ALA B 1 367 ? 130.890 161.368 179.707 1.00 73.24  ? 367 ALA B N   1 
ATOM   6494  C CA  . ALA B 1 367 ? 131.229 160.644 178.494 1.00 73.24  ? 367 ALA B CA  1 
ATOM   6495  C C   . ALA B 1 367 ? 132.682 160.194 178.539 1.00 73.24  ? 367 ALA B C   1 
ATOM   6496  O O   . ALA B 1 367 ? 133.525 160.820 179.189 1.00 73.24  ? 367 ALA B O   1 
ATOM   6497  C CB  . ALA B 1 367 ? 130.990 161.503 177.247 1.00 73.24  ? 367 ALA B CB  1 
ATOM   6498  N N   . ASP B 1 368 ? 132.966 159.099 177.840 1.00 71.75  ? 368 ASP B N   1 
ATOM   6499  C CA  . ASP B 1 368 ? 134.311 158.551 177.733 1.00 71.75  ? 368 ASP B CA  1 
ATOM   6500  C C   . ASP B 1 368 ? 134.836 158.805 176.327 1.00 71.75  ? 368 ASP B C   1 
ATOM   6501  O O   . ASP B 1 368 ? 134.188 158.435 175.342 1.00 71.75  ? 368 ASP B O   1 
ATOM   6502  C CB  . ASP B 1 368 ? 134.321 157.054 178.048 1.00 71.75  ? 368 ASP B CB  1 
ATOM   6503  C CG  . ASP B 1 368 ? 135.703 156.542 178.404 1.00 71.75  ? 368 ASP B CG  1 
ATOM   6504  O OD1 . ASP B 1 368 ? 136.643 156.755 177.611 1.00 71.75  ? 368 ASP B OD1 1 
ATOM   6505  O OD2 . ASP B 1 368 ? 135.852 155.929 179.481 1.00 71.75  ? 368 ASP B OD2 1 
ATOM   6506  N N   . LEU B 1 369 ? 136.007 159.432 176.239 1.00 70.37  ? 369 LEU B N   1 
ATOM   6507  C CA  . LEU B 1 369 ? 136.552 159.846 174.953 1.00 70.37  ? 369 LEU B CA  1 
ATOM   6508  C C   . LEU B 1 369 ? 137.440 158.792 174.307 1.00 70.37  ? 369 LEU B C   1 
ATOM   6509  O O   . LEU B 1 369 ? 137.452 158.682 173.077 1.00 70.37  ? 369 LEU B O   1 
ATOM   6510  C CB  . LEU B 1 369 ? 137.346 161.148 175.104 1.00 70.37  ? 369 LEU B CB  1 
ATOM   6511  C CG  . LEU B 1 369 ? 136.583 162.473 175.220 1.00 70.37  ? 369 LEU B CG  1 
ATOM   6512  C CD1 . LEU B 1 369 ? 135.876 162.618 176.562 1.00 70.37  ? 369 LEU B CD1 1 
ATOM   6513  C CD2 . LEU B 1 369 ? 137.523 163.644 174.981 1.00 70.37  ? 369 LEU B CD2 1 
ATOM   6514  N N   . LYS B 1 370 ? 138.184 158.017 175.099 1.00 70.01  ? 370 LYS B N   1 
ATOM   6515  C CA  . LYS B 1 370 ? 139.139 157.074 174.521 1.00 70.01  ? 370 LYS B CA  1 
ATOM   6516  C C   . LYS B 1 370 ? 138.433 155.951 173.769 1.00 70.01  ? 370 LYS B C   1 
ATOM   6517  O O   . LYS B 1 370 ? 138.799 155.628 172.633 1.00 70.01  ? 370 LYS B O   1 
ATOM   6518  C CB  . LYS B 1 370 ? 140.046 156.510 175.614 1.00 70.01  ? 370 LYS B CB  1 
ATOM   6519  C CG  . LYS B 1 370 ? 141.027 157.524 176.178 1.00 70.01  ? 370 LYS B CG  1 
ATOM   6520  C CD  . LYS B 1 370 ? 142.010 156.875 177.136 1.00 70.01  ? 370 LYS B CD  1 
ATOM   6521  C CE  . LYS B 1 370 ? 143.113 157.846 177.530 1.00 70.01  ? 370 LYS B CE  1 
ATOM   6522  N NZ  . LYS B 1 370 ? 144.151 157.198 178.377 1.00 70.01  ? 370 LYS B NZ  1 
ATOM   6523  N N   . SER B 1 371 ? 137.420 155.339 174.388 1.00 67.43  ? 371 SER B N   1 
ATOM   6524  C CA  . SER B 1 371 ? 136.707 154.246 173.734 1.00 67.43  ? 371 SER B CA  1 
ATOM   6525  C C   . SER B 1 371 ? 135.966 154.728 172.492 1.00 67.43  ? 371 SER B C   1 
ATOM   6526  O O   . SER B 1 371 ? 135.991 154.064 171.447 1.00 67.43  ? 371 SER B O   1 
ATOM   6527  C CB  . SER B 1 371 ? 135.739 153.592 174.718 1.00 67.43  ? 371 SER B CB  1 
ATOM   6528  O OG  . SER B 1 371 ? 134.960 154.566 175.388 1.00 67.43  ? 371 SER B OG  1 
ATOM   6529  N N   . THR B 1 372 ? 135.303 155.883 172.589 1.00 65.69  ? 372 THR B N   1 
ATOM   6530  C CA  . THR B 1 372 ? 134.606 156.443 171.437 1.00 65.69  ? 372 THR B CA  1 
ATOM   6531  C C   . THR B 1 372 ? 135.576 156.750 170.305 1.00 65.69  ? 372 THR B C   1 
ATOM   6532  O O   . THR B 1 372 ? 135.296 156.454 169.137 1.00 65.69  ? 372 THR B O   1 
ATOM   6533  C CB  . THR B 1 372 ? 133.851 157.708 171.846 1.00 65.69  ? 372 THR B CB  1 
ATOM   6534  O OG1 . THR B 1 372 ? 132.878 157.385 172.847 1.00 65.69  ? 372 THR B OG1 1 
ATOM   6535  C CG2 . THR B 1 372 ? 133.152 158.327 170.647 1.00 65.69  ? 372 THR B CG2 1 
ATOM   6536  N N   . GLN B 1 373 ? 136.726 157.342 170.634 1.00 65.30  ? 373 GLN B N   1 
ATOM   6537  C CA  . GLN B 1 373 ? 137.714 157.659 169.613 1.00 65.30  ? 373 GLN B CA  1 
ATOM   6538  C C   . GLN B 1 373 ? 138.255 156.395 168.961 1.00 65.30  ? 373 GLN B C   1 
ATOM   6539  O O   . GLN B 1 373 ? 138.436 156.351 167.741 1.00 65.30  ? 373 GLN B O   1 
ATOM   6540  C CB  . GLN B 1 373 ? 138.849 158.485 170.219 1.00 65.30  ? 373 GLN B CB  1 
ATOM   6541  C CG  . GLN B 1 373 ? 139.833 159.025 169.196 1.00 65.30  ? 373 GLN B CG  1 
ATOM   6542  C CD  . GLN B 1 373 ? 139.177 159.955 168.196 1.00 65.30  ? 373 GLN B CD  1 
ATOM   6543  O OE1 . GLN B 1 373 ? 138.294 160.739 168.545 1.00 65.30  ? 373 GLN B OE1 1 
ATOM   6544  N NE2 . GLN B 1 373 ? 139.603 159.870 166.942 1.00 65.30  ? 373 GLN B NE2 1 
ATOM   6545  N N   . ALA B 1 374 ? 138.516 155.354 169.755 1.00 63.29  ? 374 ALA B N   1 
ATOM   6546  C CA  . ALA B 1 374 ? 138.998 154.100 169.186 1.00 63.29  ? 374 ALA B CA  1 
ATOM   6547  C C   . ALA B 1 374 ? 137.971 153.495 168.238 1.00 63.29  ? 374 ALA B C   1 
ATOM   6548  O O   . ALA B 1 374 ? 138.319 153.038 167.140 1.00 63.29  ? 374 ALA B O   1 
ATOM   6549  C CB  . ALA B 1 374 ? 139.343 153.116 170.303 1.00 63.29  ? 374 ALA B CB  1 
ATOM   6550  N N   . ALA B 1 375 ? 136.697 153.496 168.639 1.00 62.04  ? 375 ALA B N   1 
ATOM   6551  C CA  . ALA B 1 375 ? 135.648 152.967 167.774 1.00 62.04  ? 375 ALA B CA  1 
ATOM   6552  C C   . ALA B 1 375 ? 135.549 153.762 166.477 1.00 62.04  ? 375 ALA B C   1 
ATOM   6553  O O   . ALA B 1 375 ? 135.427 153.186 165.390 1.00 62.04  ? 375 ALA B O   1 
ATOM   6554  C CB  . ALA B 1 375 ? 134.310 152.969 168.512 1.00 62.04  ? 375 ALA B CB  1 
ATOM   6555  N N   . ILE B 1 376 ? 135.606 155.093 166.573 1.00 60.96  ? 376 ILE B N   1 
ATOM   6556  C CA  . ILE B 1 376 ? 135.479 155.926 165.381 1.00 60.96  ? 376 ILE B CA  1 
ATOM   6557  C C   . ILE B 1 376 ? 136.668 155.721 164.448 1.00 60.96  ? 376 ILE B C   1 
ATOM   6558  O O   . ILE B 1 376 ? 136.502 155.625 163.226 1.00 60.96  ? 376 ILE B O   1 
ATOM   6559  C CB  . ILE B 1 376 ? 135.312 157.404 165.777 1.00 60.96  ? 376 ILE B CB  1 
ATOM   6560  C CG1 . ILE B 1 376 ? 133.966 157.618 166.472 1.00 60.96  ? 376 ILE B CG1 1 
ATOM   6561  C CG2 . ILE B 1 376 ? 135.421 158.302 164.557 1.00 60.96  ? 376 ILE B CG2 1 
ATOM   6562  C CD1 . ILE B 1 376 ? 133.779 159.012 167.024 1.00 60.96  ? 376 ILE B CD1 1 
ATOM   6563  N N   . ASP B 1 377 ? 137.881 155.644 165.001 1.00 61.26  ? 377 ASP B N   1 
ATOM   6564  C CA  . ASP B 1 377 ? 139.060 155.427 164.168 1.00 61.26  ? 377 ASP B CA  1 
ATOM   6565  C C   . ASP B 1 377 ? 139.024 154.062 163.494 1.00 61.26  ? 377 ASP B C   1 
ATOM   6566  O O   . ASP B 1 377 ? 139.433 153.927 162.335 1.00 61.26  ? 377 ASP B O   1 
ATOM   6567  C CB  . ASP B 1 377 ? 140.335 155.584 164.997 1.00 61.26  ? 377 ASP B CB  1 
ATOM   6568  C CG  . ASP B 1 377 ? 140.421 156.931 165.685 1.00 61.26  ? 377 ASP B CG  1 
ATOM   6569  O OD1 . ASP B 1 377 ? 139.461 157.721 165.571 1.00 61.26  ? 377 ASP B OD1 1 
ATOM   6570  O OD2 . ASP B 1 377 ? 141.453 157.203 166.334 1.00 61.26  ? 377 ASP B OD2 1 
ATOM   6571  N N   . GLN B 1 378 ? 138.554 153.033 164.203 1.00 57.52  ? 378 GLN B N   1 
ATOM   6572  C CA  . GLN B 1 378 ? 138.422 151.724 163.571 1.00 57.52  ? 378 GLN B CA  1 
ATOM   6573  C C   . GLN B 1 378 ? 137.375 151.748 162.463 1.00 57.52  ? 378 GLN B C   1 
ATOM   6574  O O   . GLN B 1 378 ? 137.578 151.157 161.397 1.00 57.52  ? 378 GLN B O   1 
ATOM   6575  C CB  . GLN B 1 378 ? 138.074 150.664 164.614 1.00 57.52  ? 378 GLN B CB  1 
ATOM   6576  C CG  . GLN B 1 378 ? 139.245 150.238 165.480 1.00 57.52  ? 378 GLN B CG  1 
ATOM   6577  C CD  . GLN B 1 378 ? 138.845 149.239 166.545 1.00 57.52  ? 378 GLN B CD  1 
ATOM   6578  O OE1 . GLN B 1 378 ? 138.541 148.085 166.245 1.00 57.52  ? 378 GLN B OE1 1 
ATOM   6579  N NE2 . GLN B 1 378 ? 138.842 149.678 167.798 1.00 57.52  ? 378 GLN B NE2 1 
ATOM   6580  N N   . ILE B 1 379 ? 136.249 152.422 162.699 1.00 54.82  ? 379 ILE B N   1 
ATOM   6581  C CA  . ILE B 1 379 ? 135.175 152.452 161.710 1.00 54.82  ? 379 ILE B CA  1 
ATOM   6582  C C   . ILE B 1 379 ? 135.561 153.311 160.510 1.00 54.82  ? 379 ILE B C   1 
ATOM   6583  O O   . ILE B 1 379 ? 135.303 152.941 159.358 1.00 54.82  ? 379 ILE B O   1 
ATOM   6584  C CB  . ILE B 1 379 ? 133.870 152.933 162.370 1.00 54.82  ? 379 ILE B CB  1 
ATOM   6585  C CG1 . ILE B 1 379 ? 133.270 151.809 163.217 1.00 54.82  ? 379 ILE B CG1 1 
ATOM   6586  C CG2 . ILE B 1 379 ? 132.876 153.408 161.323 1.00 54.82  ? 379 ILE B CG2 1 
ATOM   6587  C CD1 . ILE B 1 379 ? 132.192 152.264 164.166 1.00 54.82  ? 379 ILE B CD1 1 
ATOM   6588  N N   . ASN B 1 380 ? 136.185 154.461 160.755 1.00 57.74  ? 380 ASN B N   1 
ATOM   6589  C CA  . ASN B 1 380 ? 136.502 155.394 159.679 1.00 57.74  ? 380 ASN B CA  1 
ATOM   6590  C C   . ASN B 1 380 ? 137.520 154.786 158.720 1.00 57.74  ? 380 ASN B C   1 
ATOM   6591  O O   . ASN B 1 380 ? 138.527 154.212 159.146 1.00 57.74  ? 380 ASN B O   1 
ATOM   6592  C CB  . ASN B 1 380 ? 137.036 156.702 160.261 1.00 57.74  ? 380 ASN B CB  1 
ATOM   6593  C CG  . ASN B 1 380 ? 137.191 157.793 159.216 1.00 57.74  ? 380 ASN B CG  1 
ATOM   6594  O OD1 . ASN B 1 380 ? 136.926 157.583 158.032 1.00 57.74  ? 380 ASN B OD1 1 
ATOM   6595  N ND2 . ASN B 1 380 ? 137.623 158.969 159.653 1.00 57.74  ? 380 ASN B ND2 1 
ATOM   6596  N N   . GLY B 1 381 ? 137.255 154.918 157.421 1.00 53.19  ? 381 GLY B N   1 
ATOM   6597  C CA  . GLY B 1 381 ? 138.166 154.416 156.411 1.00 53.19  ? 381 GLY B CA  1 
ATOM   6598  C C   . GLY B 1 381 ? 138.219 152.911 156.290 1.00 53.19  ? 381 GLY B C   1 
ATOM   6599  O O   . GLY B 1 381 ? 139.218 152.374 155.805 1.00 53.19  ? 381 GLY B O   1 
ATOM   6600  N N   . LYS B 1 382 ? 137.166 152.211 156.716 1.00 48.52  ? 382 LYS B N   1 
ATOM   6601  C CA  . LYS B 1 382 ? 137.211 150.753 156.758 1.00 48.52  ? 382 LYS B CA  1 
ATOM   6602  C C   . LYS B 1 382 ? 137.179 150.145 155.361 1.00 48.52  ? 382 LYS B C   1 
ATOM   6603  O O   . LYS B 1 382 ? 137.897 149.177 155.085 1.00 48.52  ? 382 LYS B O   1 
ATOM   6604  C CB  . LYS B 1 382 ? 136.053 150.223 157.602 1.00 48.52  ? 382 LYS B CB  1 
ATOM   6605  C CG  . LYS B 1 382 ? 136.141 148.741 157.910 1.00 48.52  ? 382 LYS B CG  1 
ATOM   6606  C CD  . LYS B 1 382 ? 134.881 148.244 158.594 1.00 48.52  ? 382 LYS B CD  1 
ATOM   6607  C CE  . LYS B 1 382 ? 134.917 148.533 160.080 1.00 48.52  ? 382 LYS B CE  1 
ATOM   6608  N NZ  . LYS B 1 382 ? 135.922 147.681 160.766 1.00 48.52  ? 382 LYS B NZ  1 
ATOM   6609  N N   . LEU B 1 383 ? 136.356 150.693 154.465 1.00 45.80  ? 383 LEU B N   1 
ATOM   6610  C CA  . LEU B 1 383 ? 136.192 150.103 153.142 1.00 45.80  ? 383 LEU B CA  1 
ATOM   6611  C C   . LEU B 1 383 ? 137.374 150.368 152.219 1.00 45.80  ? 383 LEU B C   1 
ATOM   6612  O O   . LEU B 1 383 ? 137.567 149.620 151.255 1.00 45.80  ? 383 LEU B O   1 
ATOM   6613  C CB  . LEU B 1 383 ? 134.908 150.618 152.490 1.00 45.80  ? 383 LEU B CB  1 
ATOM   6614  C CG  . LEU B 1 383 ? 134.249 149.670 151.489 1.00 45.80  ? 383 LEU B CG  1 
ATOM   6615  C CD1 . LEU B 1 383 ? 133.798 148.397 152.182 1.00 45.80  ? 383 LEU B CD1 1 
ATOM   6616  C CD2 . LEU B 1 383 ? 133.081 150.351 150.798 1.00 45.80  ? 383 LEU B CD2 1 
ATOM   6617  N N   . ASN B 1 384 ? 138.167 151.405 152.487 1.00 49.24  ? 384 ASN B N   1 
ATOM   6618  C CA  . ASN B 1 384 ? 139.331 151.694 151.660 1.00 49.24  ? 384 ASN B CA  1 
ATOM   6619  C C   . ASN B 1 384 ? 140.461 150.694 151.859 1.00 49.24  ? 384 ASN B C   1 
ATOM   6620  O O   . ASN B 1 384 ? 141.433 150.726 151.096 1.00 49.24  ? 384 ASN B O   1 
ATOM   6621  C CB  . ASN B 1 384 ? 139.841 153.108 151.949 1.00 49.24  ? 384 ASN B CB  1 
ATOM   6622  C CG  . ASN B 1 384 ? 138.828 154.176 151.592 1.00 49.24  ? 384 ASN B CG  1 
ATOM   6623  O OD1 . ASN B 1 384 ? 138.075 154.037 150.629 1.00 49.24  ? 384 ASN B OD1 1 
ATOM   6624  N ND2 . ASN B 1 384 ? 138.806 155.252 152.368 1.00 49.24  ? 384 ASN B ND2 1 
ATOM   6625  N N   . ARG B 1 385 ? 140.363 149.819 152.859 1.00 47.20  ? 385 ARG B N   1 
ATOM   6626  C CA  . ARG B 1 385 ? 141.441 148.887 153.165 1.00 47.20  ? 385 ARG B CA  1 
ATOM   6627  C C   . ARG B 1 385 ? 141.482 147.686 152.230 1.00 47.20  ? 385 ARG B C   1 
ATOM   6628  O O   . ARG B 1 385 ? 142.521 147.022 152.149 1.00 47.20  ? 385 ARG B O   1 
ATOM   6629  C CB  . ARG B 1 385 ? 141.313 148.397 154.608 1.00 47.20  ? 385 ARG B CB  1 
ATOM   6630  C CG  . ARG B 1 385 ? 141.962 149.308 155.632 1.00 47.20  ? 385 ARG B CG  1 
ATOM   6631  C CD  . ARG B 1 385 ? 141.273 149.204 156.981 1.00 47.20  ? 385 ARG B CD  1 
ATOM   6632  N NE  . ARG B 1 385 ? 141.378 150.440 157.747 1.00 47.20  ? 385 ARG B NE  1 
ATOM   6633  C CZ  . ARG B 1 385 ? 140.565 150.779 158.737 1.00 47.20  ? 385 ARG B CZ  1 
ATOM   6634  N NH1 . ARG B 1 385 ? 139.567 149.995 159.111 1.00 47.20  ? 385 ARG B NH1 1 
ATOM   6635  N NH2 . ARG B 1 385 ? 140.757 151.933 159.368 1.00 47.20  ? 385 ARG B NH2 1 
ATOM   6636  N N   . VAL B 1 386 ? 140.390 147.386 151.525 1.00 47.23  ? 386 VAL B N   1 
ATOM   6637  C CA  . VAL B 1 386 ? 140.278 146.178 150.716 1.00 47.23  ? 386 VAL B CA  1 
ATOM   6638  C C   . VAL B 1 386 ? 140.037 146.502 149.245 1.00 47.23  ? 386 VAL B C   1 
ATOM   6639  O O   . VAL B 1 386 ? 140.634 145.885 148.358 1.00 47.23  ? 386 VAL B O   1 
ATOM   6640  C CB  . VAL B 1 386 ? 139.181 145.235 151.259 1.00 47.23  ? 386 VAL B CB  1 
ATOM   6641  C CG1 . VAL B 1 386 ? 139.620 144.624 152.577 1.00 47.23  ? 386 VAL B CG1 1 
ATOM   6642  C CG2 . VAL B 1 386 ? 137.875 145.987 151.450 1.00 47.23  ? 386 VAL B CG2 1 
ATOM   6643  N N   . ILE B 1 387 ? 139.164 147.464 148.966 1.00 49.15  ? 387 ILE B N   1 
ATOM   6644  C CA  . ILE B 1 387 ? 138.771 147.782 147.597 1.00 49.15  ? 387 ILE B CA  1 
ATOM   6645  C C   . ILE B 1 387 ? 139.450 149.075 147.167 1.00 49.15  ? 387 ILE B C   1 
ATOM   6646  O O   . ILE B 1 387 ? 139.606 150.011 147.961 1.00 49.15  ? 387 ILE B O   1 
ATOM   6647  C CB  . ILE B 1 387 ? 137.236 147.870 147.458 1.00 49.15  ? 387 ILE B CB  1 
ATOM   6648  C CG1 . ILE B 1 387 ? 136.832 147.838 145.983 1.00 49.15  ? 387 ILE B CG1 1 
ATOM   6649  C CG2 . ILE B 1 387 ? 136.682 149.108 148.150 1.00 49.15  ? 387 ILE B CG2 1 
ATOM   6650  C CD1 . ILE B 1 387 ? 135.381 147.485 145.755 1.00 49.15  ? 387 ILE B CD1 1 
ATOM   6651  N N   . GLU B 1 388 ? 139.886 149.110 145.912 1.00 55.35  ? 388 GLU B N   1 
ATOM   6652  C CA  . GLU B 1 388 ? 140.566 150.276 145.373 1.00 55.35  ? 388 GLU B CA  1 
ATOM   6653  C C   . GLU B 1 388 ? 139.575 151.416 145.154 1.00 55.35  ? 388 GLU B C   1 
ATOM   6654  O O   . GLU B 1 388 ? 138.357 151.221 145.119 1.00 55.35  ? 388 GLU B O   1 
ATOM   6655  C CB  . GLU B 1 388 ? 141.273 149.925 144.062 1.00 55.35  ? 388 GLU B CB  1 
ATOM   6656  C CG  . GLU B 1 388 ? 142.299 148.802 144.180 1.00 55.35  ? 388 GLU B CG  1 
ATOM   6657  C CD  . GLU B 1 388 ? 141.668 147.418 144.194 1.00 55.35  ? 388 GLU B CD  1 
ATOM   6658  O OE1 . GLU B 1 388 ? 140.438 147.321 144.000 1.00 55.35  ? 388 GLU B OE1 1 
ATOM   6659  O OE2 . GLU B 1 388 ? 142.402 146.429 144.405 1.00 55.35  ? 388 GLU B OE2 1 
ATOM   6660  N N   . LYS B 1 389 ? 140.117 152.626 145.006 1.00 60.17  ? 389 LYS B N   1 
ATOM   6661  C CA  . LYS B 1 389 ? 139.269 153.811 144.914 1.00 60.17  ? 389 LYS B CA  1 
ATOM   6662  C C   . LYS B 1 389 ? 138.490 153.832 143.605 1.00 60.17  ? 389 LYS B C   1 
ATOM   6663  O O   . LYS B 1 389 ? 137.256 153.753 143.601 1.00 60.17  ? 389 LYS B O   1 
ATOM   6664  C CB  . LYS B 1 389 ? 140.123 155.072 145.059 1.00 60.17  ? 389 LYS B CB  1 
ATOM   6665  C CG  . LYS B 1 389 ? 139.374 156.274 145.608 1.00 60.17  ? 389 LYS B CG  1 
ATOM   6666  C CD  . LYS B 1 389 ? 140.338 157.381 146.002 1.00 60.17  ? 389 LYS B CD  1 
ATOM   6667  C CE  . LYS B 1 389 ? 139.614 158.535 146.675 1.00 60.17  ? 389 LYS B CE  1 
ATOM   6668  N NZ  . LYS B 1 389 ? 140.564 159.559 147.191 1.00 60.17  ? 389 LYS B NZ  1 
ATOM   6669  N N   . THR B 1 390 ? 139.195 153.927 142.478 1.00 53.51  ? 390 THR B N   1 
ATOM   6670  C CA  . THR B 1 390 ? 138.571 153.926 141.163 1.00 53.51  ? 390 THR B CA  1 
ATOM   6671  C C   . THR B 1 390 ? 139.437 153.139 140.192 1.00 53.51  ? 390 THR B C   1 
ATOM   6672  O O   . THR B 1 390 ? 140.644 152.985 140.395 1.00 53.51  ? 390 THR B O   1 
ATOM   6673  C CB  . THR B 1 390 ? 138.360 155.346 140.603 1.00 53.51  ? 390 THR B CB  1 
ATOM   6674  O OG1 . THR B 1 390 ? 139.627 156.001 140.456 1.00 53.51  ? 390 THR B OG1 1 
ATOM   6675  C CG2 . THR B 1 390 ? 137.452 156.175 141.501 1.00 53.51  ? 390 THR B CG2 1 
ATOM   6676  N N   . ASN B 1 391 ? 138.804 152.642 139.133 1.00 42.29  ? 391 ASN B N   1 
ATOM   6677  C CA  . ASN B 1 391 ? 139.495 152.002 138.022 1.00 42.29  ? 391 ASN B CA  1 
ATOM   6678  C C   . ASN B 1 391 ? 139.224 152.803 136.757 1.00 42.29  ? 391 ASN B C   1 
ATOM   6679  O O   . ASN B 1 391 ? 138.064 153.050 136.409 1.00 42.29  ? 391 ASN B O   1 
ATOM   6680  C CB  . ASN B 1 391 ? 139.056 150.542 137.862 1.00 42.29  ? 391 ASN B CB  1 
ATOM   6681  C CG  . ASN B 1 391 ? 137.546 150.371 137.900 1.00 42.29  ? 391 ASN B CG  1 
ATOM   6682  O OD1 . ASN B 1 391 ? 136.799 151.337 138.034 1.00 42.29  ? 391 ASN B OD1 1 
ATOM   6683  N ND2 . ASN B 1 391 ? 137.092 149.130 137.779 1.00 42.29  ? 391 ASN B ND2 1 
ATOM   6684  N N   . GLU B 1 392 ? 140.290 153.215 136.077 1.00 36.36  ? 392 GLU B N   1 
ATOM   6685  C CA  . GLU B 1 392 ? 140.187 154.044 134.881 1.00 36.36  ? 392 GLU B CA  1 
ATOM   6686  C C   . GLU B 1 392 ? 140.252 153.147 133.651 1.00 36.36  ? 392 GLU B C   1 
ATOM   6687  O O   . GLU B 1 392 ? 141.310 152.598 133.328 1.00 36.36  ? 392 GLU B O   1 
ATOM   6688  C CB  . GLU B 1 392 ? 141.292 155.097 134.855 1.00 36.36  ? 392 GLU B CB  1 
ATOM   6689  C CG  . GLU B 1 392 ? 140.916 156.395 135.546 1.00 36.36  ? 392 GLU B CG  1 
ATOM   6690  C CD  . GLU B 1 392 ? 141.693 157.583 135.020 1.00 36.36  ? 392 GLU B CD  1 
ATOM   6691  O OE1 . GLU B 1 392 ? 142.939 157.567 135.105 1.00 36.36  ? 392 GLU B OE1 1 
ATOM   6692  O OE2 . GLU B 1 392 ? 141.057 158.536 134.521 1.00 36.36  ? 392 GLU B OE2 1 
ATOM   6693  N N   . LYS B 1 393 ? 139.119 153.001 132.970 1.00 30.28  ? 393 LYS B N   1 
ATOM   6694  C CA  . LYS B 1 393 ? 139.020 152.225 131.743 1.00 30.28  ? 393 LYS B CA  1 
ATOM   6695  C C   . LYS B 1 393 ? 138.534 153.134 130.625 1.00 30.28  ? 393 LYS B C   1 
ATOM   6696  O O   . LYS B 1 393 ? 137.593 153.911 130.811 1.00 30.28  ? 393 LYS B O   1 
ATOM   6697  C CB  . LYS B 1 393 ? 138.068 151.038 131.915 1.00 30.28  ? 393 LYS B CB  1 
ATOM   6698  C CG  . LYS B 1 393 ? 138.291 150.247 133.193 1.00 30.28  ? 393 LYS B CG  1 
ATOM   6699  C CD  . LYS B 1 393 ? 139.334 149.160 133.000 1.00 30.28  ? 393 LYS B CD  1 
ATOM   6700  C CE  . LYS B 1 393 ? 139.697 148.506 134.323 1.00 30.28  ? 393 LYS B CE  1 
ATOM   6701  N NZ  . LYS B 1 393 ? 140.959 147.724 134.231 1.00 30.28  ? 393 LYS B NZ  1 
ATOM   6702  N N   . PHE B 1 394 ? 139.181 153.042 129.462 1.00 29.49  ? 394 PHE B N   1 
ATOM   6703  C CA  . PHE B 1 394 ? 138.919 153.979 128.375 1.00 29.49  ? 394 PHE B CA  1 
ATOM   6704  C C   . PHE B 1 394 ? 138.298 153.309 127.157 1.00 29.49  ? 394 PHE B C   1 
ATOM   6705  O O   . PHE B 1 394 ? 137.203 153.701 126.744 1.00 29.49  ? 394 PHE B O   1 
ATOM   6706  C CB  . PHE B 1 394 ? 140.222 154.698 128.006 1.00 29.49  ? 394 PHE B CB  1 
ATOM   6707  C CG  . PHE B 1 394 ? 140.863 155.403 129.165 1.00 29.49  ? 394 PHE B CG  1 
ATOM   6708  C CD1 . PHE B 1 394 ? 140.237 156.481 129.766 1.00 29.49  ? 394 PHE B CD1 1 
ATOM   6709  C CD2 . PHE B 1 394 ? 142.080 154.978 129.665 1.00 29.49  ? 394 PHE B CD2 1 
ATOM   6710  C CE1 . PHE B 1 394 ? 140.818 157.129 130.835 1.00 29.49  ? 394 PHE B CE1 1 
ATOM   6711  C CE2 . PHE B 1 394 ? 142.666 155.622 130.734 1.00 29.49  ? 394 PHE B CE2 1 
ATOM   6712  C CZ  . PHE B 1 394 ? 142.033 156.698 131.320 1.00 29.49  ? 394 PHE B CZ  1 
ATOM   6713  N N   . HIS B 1 395 ? 138.947 152.308 126.573 1.00 25.79  ? 395 HIS B N   1 
ATOM   6714  C CA  . HIS B 1 395 ? 138.420 151.607 125.410 1.00 25.79  ? 395 HIS B CA  1 
ATOM   6715  C C   . HIS B 1 395 ? 138.200 150.148 125.774 1.00 25.79  ? 395 HIS B C   1 
ATOM   6716  O O   . HIS B 1 395 ? 139.090 149.505 126.341 1.00 25.79  ? 395 HIS B O   1 
ATOM   6717  C CB  . HIS B 1 395 ? 139.365 151.725 124.211 1.00 25.79  ? 395 HIS B CB  1 
ATOM   6718  C CG  . HIS B 1 395 ? 138.720 151.396 122.900 1.00 25.79  ? 395 HIS B CG  1 
ATOM   6719  N ND1 . HIS B 1 395 ? 137.697 152.148 122.364 1.00 25.79  ? 395 HIS B ND1 1 
ATOM   6720  C CD2 . HIS B 1 395 ? 138.951 150.394 122.019 1.00 25.79  ? 395 HIS B CD2 1 
ATOM   6721  C CE1 . HIS B 1 395 ? 137.326 151.624 121.209 1.00 25.79  ? 395 HIS B CE1 1 
ATOM   6722  N NE2 . HIS B 1 395 ? 138.071 150.559 120.977 1.00 25.79  ? 395 HIS B NE2 1 
ATOM   6723  N N   . GLN B 1 396 ? 137.019 149.630 125.446 1.00 26.64  ? 396 GLN B N   1 
ATOM   6724  C CA  . GLN B 1 396 ? 136.622 148.283 125.832 1.00 26.64  ? 396 GLN B CA  1 
ATOM   6725  C C   . GLN B 1 396 ? 135.893 147.641 124.656 1.00 26.64  ? 396 GLN B C   1 
ATOM   6726  O O   . GLN B 1 396 ? 135.949 148.127 123.523 1.00 26.64  ? 396 GLN B O   1 
ATOM   6727  C CB  . GLN B 1 396 ? 135.758 148.315 127.100 1.00 26.64  ? 396 GLN B CB  1 
ATOM   6728  C CG  . GLN B 1 396 ? 136.495 148.771 128.349 1.00 26.64  ? 396 GLN B CG  1 
ATOM   6729  C CD  . GLN B 1 396 ? 135.596 149.509 129.318 1.00 26.64  ? 396 GLN B CD  1 
ATOM   6730  O OE1 . GLN B 1 396 ? 134.825 148.897 130.056 1.00 26.64  ? 396 GLN B OE1 1 
ATOM   6731  N NE2 . GLN B 1 396 ? 135.690 150.832 129.321 1.00 26.64  ? 396 GLN B NE2 1 
ATOM   6732  N N   . ILE B 1 397 ? 135.215 146.529 124.931 1.00 25.00  ? 397 ILE B N   1 
ATOM   6733  C CA  . ILE B 1 397 ? 134.442 145.810 123.925 1.00 25.00  ? 397 ILE B CA  1 
ATOM   6734  C C   . ILE B 1 397 ? 133.042 146.401 123.831 1.00 25.00  ? 397 ILE B C   1 
ATOM   6735  O O   . ILE B 1 397 ? 132.613 147.155 124.711 1.00 25.00  ? 397 ILE B O   1 
ATOM   6736  C CB  . ILE B 1 397 ? 134.381 144.306 124.245 1.00 25.00  ? 397 ILE B CB  1 
ATOM   6737  C CG1 . ILE B 1 397 ? 133.679 144.078 125.585 1.00 25.00  ? 397 ILE B CG1 1 
ATOM   6738  C CG2 . ILE B 1 397 ? 135.775 143.712 124.260 1.00 25.00  ? 397 ILE B CG2 1 
ATOM   6739  C CD1 . ILE B 1 397 ? 133.109 142.691 125.751 1.00 25.00  ? 397 ILE B CD1 1 
ATOM   6740  N N   . GLU B 1 398 ? 132.325 146.070 122.760 1.00 26.04  ? 398 GLU B N   1 
ATOM   6741  C CA  . GLU B 1 398 ? 130.937 146.484 122.616 1.00 26.04  ? 398 GLU B CA  1 
ATOM   6742  C C   . GLU B 1 398 ? 130.037 145.617 123.484 1.00 26.04  ? 398 GLU B C   1 
ATOM   6743  O O   . GLU B 1 398 ? 130.275 144.418 123.649 1.00 26.04  ? 398 GLU B O   1 
ATOM   6744  C CB  . GLU B 1 398 ? 130.498 146.397 121.156 1.00 26.04  ? 398 GLU B CB  1 
ATOM   6745  C CG  . GLU B 1 398 ? 131.212 147.368 120.235 1.00 26.04  ? 398 GLU B CG  1 
ATOM   6746  C CD  . GLU B 1 398 ? 130.914 148.811 120.571 1.00 26.04  ? 398 GLU B CD  1 
ATOM   6747  O OE1 . GLU B 1 398 ? 129.722 149.157 120.700 1.00 26.04  ? 398 GLU B OE1 1 
ATOM   6748  O OE2 . GLU B 1 398 ? 131.870 149.602 120.704 1.00 26.04  ? 398 GLU B OE2 1 
ATOM   6749  N N   . LYS B 1 399 ? 128.992 146.231 124.038 1.00 24.86  ? 399 LYS B N   1 
ATOM   6750  C CA  . LYS B 1 399 ? 128.091 145.546 124.952 1.00 24.86  ? 399 LYS B CA  1 
ATOM   6751  C C   . LYS B 1 399 ? 126.636 145.580 124.509 1.00 24.86  ? 399 LYS B C   1 
ATOM   6752  O O   . LYS B 1 399 ? 125.793 144.954 125.162 1.00 24.86  ? 399 LYS B O   1 
ATOM   6753  C CB  . LYS B 1 399 ? 128.223 146.140 126.361 1.00 24.86  ? 399 LYS B CB  1 
ATOM   6754  C CG  . LYS B 1 399 ? 129.535 145.780 127.037 1.00 24.86  ? 399 LYS B CG  1 
ATOM   6755  C CD  . LYS B 1 399 ? 129.878 146.731 128.162 1.00 24.86  ? 399 LYS B CD  1 
ATOM   6756  C CE  . LYS B 1 399 ? 131.327 146.559 128.586 1.00 24.86  ? 399 LYS B CE  1 
ATOM   6757  N NZ  . LYS B 1 399 ? 131.671 147.393 129.767 1.00 24.86  ? 399 LYS B NZ  1 
ATOM   6758  N N   . GLU B 1 400 ? 126.313 146.286 123.428 1.00 26.60  ? 400 GLU B N   1 
ATOM   6759  C CA  . GLU B 1 400 ? 124.969 146.291 122.872 1.00 26.60  ? 400 GLU B CA  1 
ATOM   6760  C C   . GLU B 1 400 ? 125.063 146.163 121.360 1.00 26.60  ? 400 GLU B C   1 
ATOM   6761  O O   . GLU B 1 400 ? 125.953 146.745 120.735 1.00 26.60  ? 400 GLU B O   1 
ATOM   6762  C CB  . GLU B 1 400 ? 124.202 147.563 123.254 1.00 26.60  ? 400 GLU B CB  1 
ATOM   6763  C CG  . GLU B 1 400 ? 123.623 147.529 124.658 1.00 26.60  ? 400 GLU B CG  1 
ATOM   6764  C CD  . GLU B 1 400 ? 122.858 148.788 125.008 1.00 26.60  ? 400 GLU B CD  1 
ATOM   6765  O OE1 . GLU B 1 400 ? 122.201 149.356 124.111 1.00 26.60  ? 400 GLU B OE1 1 
ATOM   6766  O OE2 . GLU B 1 400 ? 122.911 149.210 126.181 1.00 26.60  ? 400 GLU B OE2 1 
ATOM   6767  N N   . PHE B 1 401 ? 124.144 145.395 120.779 1.00 27.52  ? 401 PHE B N   1 
ATOM   6768  C CA  . PHE B 1 401 ? 124.182 145.062 119.363 1.00 27.52  ? 401 PHE B CA  1 
ATOM   6769  C C   . PHE B 1 401 ? 122.799 145.241 118.756 1.00 27.52  ? 401 PHE B C   1 
ATOM   6770  O O   . PHE B 1 401 ? 121.790 144.898 119.376 1.00 27.52  ? 401 PHE B O   1 
ATOM   6771  C CB  . PHE B 1 401 ? 124.670 143.624 119.148 1.00 27.52  ? 401 PHE B CB  1 
ATOM   6772  C CG  . PHE B 1 401 ? 125.868 143.259 119.982 1.00 27.52  ? 401 PHE B CG  1 
ATOM   6773  C CD1 . PHE B 1 401 ? 125.711 142.734 121.254 1.00 27.52  ? 401 PHE B CD1 1 
ATOM   6774  C CD2 . PHE B 1 401 ? 127.150 143.444 119.494 1.00 27.52  ? 401 PHE B CD2 1 
ATOM   6775  C CE1 . PHE B 1 401 ? 126.808 142.401 122.022 1.00 27.52  ? 401 PHE B CE1 1 
ATOM   6776  C CE2 . PHE B 1 401 ? 128.250 143.111 120.258 1.00 27.52  ? 401 PHE B CE2 1 
ATOM   6777  C CZ  . PHE B 1 401 ? 128.077 142.590 121.523 1.00 27.52  ? 401 PHE B CZ  1 
ATOM   6778  N N   . SER B 1 402 ? 122.760 145.781 117.538 1.00 33.27  ? 402 SER B N   1 
ATOM   6779  C CA  . SER B 1 402 ? 121.507 146.040 116.844 1.00 33.27  ? 402 SER B CA  1 
ATOM   6780  C C   . SER B 1 402 ? 121.153 144.974 115.816 1.00 33.27  ? 402 SER B C   1 
ATOM   6781  O O   . SER B 1 402 ? 120.137 145.117 115.126 1.00 33.27  ? 402 SER B O   1 
ATOM   6782  C CB  . SER B 1 402 ? 121.556 147.411 116.158 1.00 33.27  ? 402 SER B CB  1 
ATOM   6783  O OG  . SER B 1 402 ? 122.429 147.392 115.043 1.00 33.27  ? 402 SER B OG  1 
ATOM   6784  N N   . GLU B 1 403 ? 121.953 143.918 115.695 1.00 37.72  ? 403 GLU B N   1 
ATOM   6785  C CA  . GLU B 1 403 ? 121.674 142.836 114.763 1.00 37.72  ? 403 GLU B CA  1 
ATOM   6786  C C   . GLU B 1 403 ? 122.309 141.554 115.281 1.00 37.72  ? 403 GLU B C   1 
ATOM   6787  O O   . GLU B 1 403 ? 123.211 141.579 116.122 1.00 37.72  ? 403 GLU B O   1 
ATOM   6788  C CB  . GLU B 1 403 ? 122.189 143.154 113.355 1.00 37.72  ? 403 GLU B CB  1 
ATOM   6789  C CG  . GLU B 1 403 ? 123.699 143.216 113.246 1.00 37.72  ? 403 GLU B CG  1 
ATOM   6790  C CD  . GLU B 1 403 ? 124.161 143.694 111.886 1.00 37.72  ? 403 GLU B CD  1 
ATOM   6791  O OE1 . GLU B 1 403 ? 123.414 144.459 111.241 1.00 37.72  ? 403 GLU B OE1 1 
ATOM   6792  O OE2 . GLU B 1 403 ? 125.270 143.305 111.462 1.00 37.72  ? 403 GLU B OE2 1 
ATOM   6793  N N   . VAL B 1 404 ? 121.827 140.428 114.767 1.00 34.81  ? 404 VAL B N   1 
ATOM   6794  C CA  . VAL B 1 404 ? 122.315 139.116 115.173 1.00 34.81  ? 404 VAL B CA  1 
ATOM   6795  C C   . VAL B 1 404 ? 123.451 138.699 114.248 1.00 34.81  ? 404 VAL B C   1 
ATOM   6796  O O   . VAL B 1 404 ? 123.331 138.779 113.020 1.00 34.81  ? 404 VAL B O   1 
ATOM   6797  C CB  . VAL B 1 404 ? 121.178 138.079 115.172 1.00 34.81  ? 404 VAL B CB  1 
ATOM   6798  C CG1 . VAL B 1 404 ? 120.215 138.356 116.312 1.00 34.81  ? 404 VAL B CG1 1 
ATOM   6799  C CG2 . VAL B 1 404 ? 120.434 138.097 113.850 1.00 34.81  ? 404 VAL B CG2 1 
ATOM   6800  N N   . GLU B 1 405 ? 124.564 138.274 114.839 1.00 33.59  ? 405 GLU B N   1 
ATOM   6801  C CA  . GLU B 1 405 ? 125.750 137.874 114.093 1.00 33.59  ? 405 GLU B CA  1 
ATOM   6802  C C   . GLU B 1 405 ? 126.173 136.439 114.354 1.00 33.59  ? 405 GLU B C   1 
ATOM   6803  O O   . GLU B 1 405 ? 126.514 135.724 113.410 1.00 33.59  ? 405 GLU B O   1 
ATOM   6804  C CB  . GLU B 1 405 ? 126.917 138.814 114.419 1.00 33.59  ? 405 GLU B CB  1 
ATOM   6805  C CG  . GLU B 1 405 ? 126.641 140.271 114.101 1.00 33.59  ? 405 GLU B CG  1 
ATOM   6806  C CD  . GLU B 1 405 ? 127.657 141.204 114.724 1.00 33.59  ? 405 GLU B CD  1 
ATOM   6807  O OE1 . GLU B 1 405 ? 128.833 141.166 114.308 1.00 33.59  ? 405 GLU B OE1 1 
ATOM   6808  O OE2 . GLU B 1 405 ? 127.278 141.976 115.628 1.00 33.59  ? 405 GLU B OE2 1 
ATOM   6809  N N   . GLY B 1 406 ? 126.163 135.994 115.608 1.00 28.02  ? 406 GLY B N   1 
ATOM   6810  C CA  . GLY B 1 406 ? 126.506 134.618 115.907 1.00 28.02  ? 406 GLY B CA  1 
ATOM   6811  C C   . GLY B 1 406 ? 127.580 134.416 116.957 1.00 28.02  ? 406 GLY B C   1 
ATOM   6812  O O   . GLY B 1 406 ? 127.392 134.758 118.127 1.00 28.02  ? 406 GLY B O   1 
ATOM   6813  N N   . ARG B 1 407 ? 128.718 133.861 116.534 1.00 26.80  ? 407 ARG B N   1 
ATOM   6814  C CA  . ARG B 1 407 ? 129.703 133.323 117.470 1.00 26.80  ? 407 ARG B CA  1 
ATOM   6815  C C   . ARG B 1 407 ? 130.356 134.417 118.313 1.00 26.80  ? 407 ARG B C   1 
ATOM   6816  O O   . ARG B 1 407 ? 130.416 134.314 119.546 1.00 26.80  ? 407 ARG B O   1 
ATOM   6817  C CB  . ARG B 1 407 ? 130.756 132.538 116.686 1.00 26.80  ? 407 ARG B CB  1 
ATOM   6818  C CG  . ARG B 1 407 ? 131.252 131.277 117.358 1.00 26.80  ? 407 ARG B CG  1 
ATOM   6819  C CD  . ARG B 1 407 ? 132.243 130.556 116.462 1.00 26.80  ? 407 ARG B CD  1 
ATOM   6820  N NE  . ARG B 1 407 ? 133.109 129.655 117.212 1.00 26.80  ? 407 ARG B NE  1 
ATOM   6821  C CZ  . ARG B 1 407 ? 133.915 128.761 116.658 1.00 26.80  ? 407 ARG B CZ  1 
ATOM   6822  N NH1 . ARG B 1 407 ? 133.987 128.615 115.345 1.00 26.80  ? 407 ARG B NH1 1 
ATOM   6823  N NH2 . ARG B 1 407 ? 134.668 127.994 117.440 1.00 26.80  ? 407 ARG B NH2 1 
ATOM   6824  N N   . ILE B 1 408 ? 130.855 135.473 117.666 1.00 27.33  ? 408 ILE B N   1 
ATOM   6825  C CA  . ILE B 1 408 ? 131.619 136.495 118.379 1.00 27.33  ? 408 ILE B CA  1 
ATOM   6826  C C   . ILE B 1 408 ? 130.719 137.282 119.324 1.00 27.33  ? 408 ILE B C   1 
ATOM   6827  O O   . ILE B 1 408 ? 131.116 137.620 120.448 1.00 27.33  ? 408 ILE B O   1 
ATOM   6828  C CB  . ILE B 1 408 ? 132.335 137.419 117.378 1.00 27.33  ? 408 ILE B CB  1 
ATOM   6829  C CG1 . ILE B 1 408 ? 132.961 136.601 116.248 1.00 27.33  ? 408 ILE B CG1 1 
ATOM   6830  C CG2 . ILE B 1 408 ? 133.398 138.244 118.081 1.00 27.33  ? 408 ILE B CG2 1 
ATOM   6831  C CD1 . ILE B 1 408 ? 134.053 135.661 116.705 1.00 27.33  ? 408 ILE B CD1 1 
ATOM   6832  N N   . GLN B 1 409 ? 129.499 137.592 118.883 1.00 27.51  ? 409 GLN B N   1 
ATOM   6833  C CA  . GLN B 1 409 ? 128.549 138.285 119.745 1.00 27.51  ? 409 GLN B CA  1 
ATOM   6834  C C   . GLN B 1 409 ? 128.214 137.447 120.972 1.00 27.51  ? 409 GLN B C   1 
ATOM   6835  O O   . GLN B 1 409 ? 128.128 137.971 122.091 1.00 27.51  ? 409 GLN B O   1 
ATOM   6836  C CB  . GLN B 1 409 ? 127.286 138.615 118.951 1.00 27.51  ? 409 GLN B CB  1 
ATOM   6837  C CG  . GLN B 1 409 ? 126.366 139.617 119.610 1.00 27.51  ? 409 GLN B CG  1 
ATOM   6838  C CD  . GLN B 1 409 ? 125.293 140.116 118.668 1.00 27.51  ? 409 GLN B CD  1 
ATOM   6839  O OE1 . GLN B 1 409 ? 124.109 140.112 118.998 1.00 27.51  ? 409 GLN B OE1 1 
ATOM   6840  N NE2 . GLN B 1 409 ? 125.703 140.549 117.483 1.00 27.51  ? 409 GLN B NE2 1 
ATOM   6841  N N   . ASP B 1 410 ? 128.031 136.139 120.779 1.00 26.25  ? 410 ASP B N   1 
ATOM   6842  C CA  . ASP B 1 410 ? 127.767 135.245 121.900 1.00 26.25  ? 410 ASP B CA  1 
ATOM   6843  C C   . ASP B 1 410 ? 128.929 135.237 122.883 1.00 26.25  ? 410 ASP B C   1 
ATOM   6844  O O   . ASP B 1 410 ? 128.721 135.281 124.102 1.00 26.25  ? 410 ASP B O   1 
ATOM   6845  C CB  . ASP B 1 410 ? 127.493 133.832 121.389 1.00 26.25  ? 410 ASP B CB  1 
ATOM   6846  C CG  . ASP B 1 410 ? 126.169 133.720 120.664 1.00 26.25  ? 410 ASP B CG  1 
ATOM   6847  O OD1 . ASP B 1 410 ? 125.356 134.664 120.754 1.00 26.25  ? 410 ASP B OD1 1 
ATOM   6848  O OD2 . ASP B 1 410 ? 125.944 132.689 119.997 1.00 26.25  ? 410 ASP B OD2 1 
ATOM   6849  N N   . LEU B 1 411 ? 130.162 135.176 122.371 1.00 24.16  ? 411 LEU B N   1 
ATOM   6850  C CA  . LEU B 1 411 ? 131.324 135.178 123.256 1.00 24.16  ? 411 LEU B CA  1 
ATOM   6851  C C   . LEU B 1 411 ? 131.417 136.476 124.052 1.00 24.16  ? 411 LEU B C   1 
ATOM   6852  O O   . LEU B 1 411 ? 131.707 136.457 125.256 1.00 24.16  ? 411 LEU B O   1 
ATOM   6853  C CB  . LEU B 1 411 ? 132.600 134.949 122.445 1.00 24.16  ? 411 LEU B CB  1 
ATOM   6854  C CG  . LEU B 1 411 ? 133.872 134.628 123.235 1.00 24.16  ? 411 LEU B CG  1 
ATOM   6855  C CD1 . LEU B 1 411 ? 133.637 133.487 124.209 1.00 24.16  ? 411 LEU B CD1 1 
ATOM   6856  C CD2 . LEU B 1 411 ? 135.015 134.300 122.293 1.00 24.16  ? 411 LEU B CD2 1 
ATOM   6857  N N   . GLU B 1 412 ? 131.169 137.614 123.398 1.00 25.35  ? 412 GLU B N   1 
ATOM   6858  C CA  . GLU B 1 412 ? 131.228 138.895 124.098 1.00 25.35  ? 412 GLU B CA  1 
ATOM   6859  C C   . GLU B 1 412 ? 130.161 138.985 125.184 1.00 25.35  ? 412 GLU B C   1 
ATOM   6860  O O   . GLU B 1 412 ? 130.437 139.437 126.307 1.00 25.35  ? 412 GLU B O   1 
ATOM   6861  C CB  . GLU B 1 412 ? 131.075 140.040 123.098 1.00 25.35  ? 412 GLU B CB  1 
ATOM   6862  C CG  . GLU B 1 412 ? 132.287 140.243 122.210 1.00 25.35  ? 412 GLU B CG  1 
ATOM   6863  C CD  . GLU B 1 412 ? 131.949 140.949 120.916 1.00 25.35  ? 412 GLU B CD  1 
ATOM   6864  O OE1 . GLU B 1 412 ? 130.747 141.122 120.629 1.00 25.35  ? 412 GLU B OE1 1 
ATOM   6865  O OE2 . GLU B 1 412 ? 132.885 141.328 120.181 1.00 25.35  ? 412 GLU B OE2 1 
ATOM   6866  N N   . LYS B 1 413 ? 128.937 138.551 124.869 1.00 23.63  ? 413 LYS B N   1 
ATOM   6867  C CA  . LYS B 1 413 ? 127.870 138.558 125.864 1.00 23.63  ? 413 LYS B CA  1 
ATOM   6868  C C   . LYS B 1 413 ? 128.216 137.661 127.045 1.00 23.63  ? 413 LYS B C   1 
ATOM   6869  O O   . LYS B 1 413 ? 127.985 138.029 128.205 1.00 23.63  ? 413 LYS B O   1 
ATOM   6870  C CB  . LYS B 1 413 ? 126.557 138.117 125.221 1.00 23.63  ? 413 LYS B CB  1 
ATOM   6871  C CG  . LYS B 1 413 ? 125.925 139.164 124.324 1.00 23.63  ? 413 LYS B CG  1 
ATOM   6872  C CD  . LYS B 1 413 ? 124.792 138.573 123.508 1.00 23.63  ? 413 LYS B CD  1 
ATOM   6873  C CE  . LYS B 1 413 ? 123.953 139.661 122.865 1.00 23.63  ? 413 LYS B CE  1 
ATOM   6874  N NZ  . LYS B 1 413 ? 122.639 139.145 122.401 1.00 23.63  ? 413 LYS B NZ  1 
ATOM   6875  N N   . TYR B 1 414 ? 128.773 136.480 126.767 1.00 22.90  ? 414 TYR B N   1 
ATOM   6876  C CA  . TYR B 1 414 ? 129.163 135.562 127.832 1.00 22.90  ? 414 TYR B CA  1 
ATOM   6877  C C   . TYR B 1 414 ? 130.215 136.185 128.742 1.00 22.90  ? 414 TYR B C   1 
ATOM   6878  O O   . TYR B 1 414 ? 130.116 136.096 129.974 1.00 22.90  ? 414 TYR B O   1 
ATOM   6879  C CB  . TYR B 1 414 ? 129.679 134.262 127.216 1.00 22.90  ? 414 TYR B CB  1 
ATOM   6880  C CG  . TYR B 1 414 ? 129.857 133.123 128.190 1.00 22.90  ? 414 TYR B CG  1 
ATOM   6881  C CD1 . TYR B 1 414 ? 128.762 132.436 128.693 1.00 22.90  ? 414 TYR B CD1 1 
ATOM   6882  C CD2 . TYR B 1 414 ? 131.122 132.723 128.595 1.00 22.90  ? 414 TYR B CD2 1 
ATOM   6883  C CE1 . TYR B 1 414 ? 128.921 131.392 129.577 1.00 22.90  ? 414 TYR B CE1 1 
ATOM   6884  C CE2 . TYR B 1 414 ? 131.292 131.681 129.480 1.00 22.90  ? 414 TYR B CE2 1 
ATOM   6885  C CZ  . TYR B 1 414 ? 130.188 131.019 129.967 1.00 22.90  ? 414 TYR B CZ  1 
ATOM   6886  O OH  . TYR B 1 414 ? 130.354 129.977 130.849 1.00 22.90  ? 414 TYR B OH  1 
ATOM   6887  N N   . VAL B 1 415 ? 131.225 136.828 128.150 1.00 23.01  ? 415 VAL B N   1 
ATOM   6888  C CA  . VAL B 1 415 ? 132.289 137.442 128.944 1.00 23.01  ? 415 VAL B CA  1 
ATOM   6889  C C   . VAL B 1 415 ? 131.718 138.527 129.850 1.00 23.01  ? 415 VAL B C   1 
ATOM   6890  O O   . VAL B 1 415 ? 132.014 138.582 131.056 1.00 23.01  ? 415 VAL B O   1 
ATOM   6891  C CB  . VAL B 1 415 ? 133.388 137.998 128.020 1.00 23.01  ? 415 VAL B CB  1 
ATOM   6892  C CG1 . VAL B 1 415 ? 134.333 138.905 128.791 1.00 23.01  ? 415 VAL B CG1 1 
ATOM   6893  C CG2 . VAL B 1 415 ? 134.153 136.864 127.361 1.00 23.01  ? 415 VAL B CG2 1 
ATOM   6894  N N   . GLU B 1 416 ? 130.876 139.399 129.286 1.00 24.21  ? 416 GLU B N   1 
ATOM   6895  C CA  . GLU B 1 416 ? 130.322 140.493 130.079 1.00 24.21  ? 416 GLU B CA  1 
ATOM   6896  C C   . GLU B 1 416 ? 129.440 139.971 131.210 1.00 24.21  ? 416 GLU B C   1 
ATOM   6897  O O   . GLU B 1 416 ? 129.510 140.468 132.343 1.00 24.21  ? 416 GLU B O   1 
ATOM   6898  C CB  . GLU B 1 416 ? 129.540 141.450 129.180 1.00 24.21  ? 416 GLU B CB  1 
ATOM   6899  C CG  . GLU B 1 416 ? 129.093 142.731 129.870 1.00 24.21  ? 416 GLU B CG  1 
ATOM   6900  C CD  . GLU B 1 416 ? 130.233 143.465 130.551 1.00 24.21  ? 416 GLU B CD  1 
ATOM   6901  O OE1 . GLU B 1 416 ? 131.349 143.489 129.992 1.00 24.21  ? 416 GLU B OE1 1 
ATOM   6902  O OE2 . GLU B 1 416 ? 130.015 144.017 131.650 1.00 24.21  ? 416 GLU B OE2 1 
ATOM   6903  N N   . ASP B 1 417 ? 128.610 138.964 130.924 1.00 24.83  ? 417 ASP B N   1 
ATOM   6904  C CA  . ASP B 1 417 ? 127.728 138.419 131.952 1.00 24.83  ? 417 ASP B CA  1 
ATOM   6905  C C   . ASP B 1 417 ? 128.523 137.773 133.082 1.00 24.83  ? 417 ASP B C   1 
ATOM   6906  O O   . ASP B 1 417 ? 128.192 137.944 134.265 1.00 24.83  ? 417 ASP B O   1 
ATOM   6907  C CB  . ASP B 1 417 ? 126.762 137.416 131.322 1.00 24.83  ? 417 ASP B CB  1 
ATOM   6908  C CG  . ASP B 1 417 ? 125.722 136.914 132.300 1.00 24.83  ? 417 ASP B CG  1 
ATOM   6909  O OD1 . ASP B 1 417 ? 124.791 137.681 132.621 1.00 24.83  ? 417 ASP B OD1 1 
ATOM   6910  O OD2 . ASP B 1 417 ? 125.829 135.749 132.738 1.00 24.83  ? 417 ASP B OD2 1 
ATOM   6911  N N   . THR B 1 418 ? 129.580 137.031 132.736 1.00 22.08  ? 418 THR B N   1 
ATOM   6912  C CA  . THR B 1 418 ? 130.421 136.416 133.759 1.00 22.08  ? 418 THR B CA  1 
ATOM   6913  C C   . THR B 1 418 ? 131.053 137.474 134.656 1.00 22.08  ? 418 THR B C   1 
ATOM   6914  O O   . THR B 1 418 ? 131.056 137.345 135.891 1.00 22.08  ? 418 THR B O   1 
ATOM   6915  C CB  . THR B 1 418 ? 131.500 135.560 133.094 1.00 22.08  ? 418 THR B CB  1 
ATOM   6916  O OG1 . THR B 1 418 ? 130.882 134.551 132.286 1.00 22.08  ? 418 THR B OG1 1 
ATOM   6917  C CG2 . THR B 1 418 ? 132.379 134.895 134.139 1.00 22.08  ? 418 THR B CG2 1 
ATOM   6918  N N   . LYS B 1 419 ? 131.582 138.540 134.047 1.00 20.53  ? 419 LYS B N   1 
ATOM   6919  C CA  . LYS B 1 419 ? 132.197 139.607 134.832 1.00 20.53  ? 419 LYS B CA  1 
ATOM   6920  C C   . LYS B 1 419 ? 131.190 140.248 135.782 1.00 20.53  ? 419 LYS B C   1 
ATOM   6921  O O   . LYS B 1 419 ? 131.491 140.471 136.967 1.00 20.53  ? 419 LYS B O   1 
ATOM   6922  C CB  . LYS B 1 419 ? 132.798 140.653 133.893 1.00 20.53  ? 419 LYS B CB  1 
ATOM   6923  C CG  . LYS B 1 419 ? 133.231 141.938 134.566 1.00 20.53  ? 419 LYS B CG  1 
ATOM   6924  C CD  . LYS B 1 419 ? 133.857 142.882 133.560 1.00 20.53  ? 419 LYS B CD  1 
ATOM   6925  C CE  . LYS B 1 419 ? 134.652 143.976 134.244 1.00 20.53  ? 419 LYS B CE  1 
ATOM   6926  N NZ  . LYS B 1 419 ? 134.359 145.310 133.658 1.00 20.53  ? 419 LYS B NZ  1 
ATOM   6927  N N   . VAL B 1 420 ? 129.984 140.536 135.283 1.00 20.94  ? 420 VAL B N   1 
ATOM   6928  C CA  . VAL B 1 420 ? 128.971 141.185 136.113 1.00 20.94  ? 420 VAL B CA  1 
ATOM   6929  C C   . VAL B 1 420 ? 128.597 140.302 137.298 1.00 20.94  ? 420 VAL B C   1 
ATOM   6930  O O   . VAL B 1 420 ? 128.505 140.776 138.440 1.00 20.94  ? 420 VAL B O   1 
ATOM   6931  C CB  . VAL B 1 420 ? 127.738 141.548 135.263 1.00 20.94  ? 420 VAL B CB  1 
ATOM   6932  C CG1 . VAL B 1 420 ? 126.590 141.997 136.151 1.00 20.94  ? 420 VAL B CG1 1 
ATOM   6933  C CG2 . VAL B 1 420 ? 128.088 142.634 134.261 1.00 20.94  ? 420 VAL B CG2 1 
ATOM   6934  N N   . ASP B 1 421 ? 128.382 139.006 137.049 1.00 22.30  ? 421 ASP B N   1 
ATOM   6935  C CA  . ASP B 1 421 ? 127.999 138.106 138.134 1.00 22.30  ? 421 ASP B CA  1 
ATOM   6936  C C   . ASP B 1 421 ? 129.087 138.020 139.199 1.00 22.30  ? 421 ASP B C   1 
ATOM   6937  O O   . ASP B 1 421 ? 128.800 138.086 140.406 1.00 22.30  ? 421 ASP B O   1 
ATOM   6938  C CB  . ASP B 1 421 ? 127.691 136.718 137.576 1.00 22.30  ? 421 ASP B CB  1 
ATOM   6939  C CG  . ASP B 1 421 ? 126.372 136.666 136.835 1.00 22.30  ? 421 ASP B CG  1 
ATOM   6940  O OD1 . ASP B 1 421 ? 125.576 137.617 136.968 1.00 22.30  ? 421 ASP B OD1 1 
ATOM   6941  O OD2 . ASP B 1 421 ? 126.130 135.673 136.119 1.00 22.30  ? 421 ASP B OD2 1 
ATOM   6942  N N   . LEU B 1 422 ? 130.347 137.880 138.771 1.00 20.95  ? 422 LEU B N   1 
ATOM   6943  C CA  . LEU B 1 422 ? 131.433 137.760 139.738 1.00 20.95  ? 422 LEU B CA  1 
ATOM   6944  C C   . LEU B 1 422 ? 131.554 139.016 140.594 1.00 20.95  ? 422 LEU B C   1 
ATOM   6945  O O   . LEU B 1 422 ? 131.710 138.931 141.822 1.00 20.95  ? 422 LEU B O   1 
ATOM   6946  C CB  . LEU B 1 422 ? 132.746 137.464 139.015 1.00 20.95  ? 422 LEU B CB  1 
ATOM   6947  C CG  . LEU B 1 422 ? 132.970 136.005 138.610 1.00 20.95  ? 422 LEU B CG  1 
ATOM   6948  C CD1 . LEU B 1 422 ? 133.956 135.909 137.461 1.00 20.95  ? 422 LEU B CD1 1 
ATOM   6949  C CD2 . LEU B 1 422 ? 133.446 135.179 139.792 1.00 20.95  ? 422 LEU B CD2 1 
ATOM   6950  N N   . TRP B 1 423 ? 131.460 140.196 139.972 1.00 20.96  ? 423 TRP B N   1 
ATOM   6951  C CA  . TRP B 1 423 ? 131.605 141.418 140.758 1.00 20.96  ? 423 TRP B CA  1 
ATOM   6952  C C   . TRP B 1 423 ? 130.423 141.636 141.699 1.00 20.96  ? 423 TRP B C   1 
ATOM   6953  O O   . TRP B 1 423 ? 130.607 142.146 142.813 1.00 20.96  ? 423 TRP B O   1 
ATOM   6954  C CB  . TRP B 1 423 ? 131.805 142.621 139.839 1.00 20.96  ? 423 TRP B CB  1 
ATOM   6955  C CG  . TRP B 1 423 ? 133.250 142.834 139.493 1.00 20.96  ? 423 TRP B CG  1 
ATOM   6956  C CD1 . TRP B 1 423 ? 133.816 142.754 138.256 1.00 20.96  ? 423 TRP B CD1 1 
ATOM   6957  C CD2 . TRP B 1 423 ? 134.318 143.124 140.404 1.00 20.96  ? 423 TRP B CD2 1 
ATOM   6958  N NE1 . TRP B 1 423 ? 135.165 142.993 138.336 1.00 20.96  ? 423 TRP B NE1 1 
ATOM   6959  C CE2 . TRP B 1 423 ? 135.499 143.222 139.644 1.00 20.96  ? 423 TRP B CE2 1 
ATOM   6960  C CE3 . TRP B 1 423 ? 134.388 143.319 141.787 1.00 20.96  ? 423 TRP B CE3 1 
ATOM   6961  C CZ2 . TRP B 1 423 ? 136.735 143.505 140.220 1.00 20.96  ? 423 TRP B CZ2 1 
ATOM   6962  C CZ3 . TRP B 1 423 ? 135.615 143.600 142.355 1.00 20.96  ? 423 TRP B CZ3 1 
ATOM   6963  C CH2 . TRP B 1 423 ? 136.772 143.688 141.574 1.00 20.96  ? 423 TRP B CH2 1 
ATOM   6964  N N   . SER B 1 424 ? 129.211 141.248 141.286 1.00 21.71  ? 424 SER B N   1 
ATOM   6965  C CA  . SER B 1 424 ? 128.067 141.359 142.188 1.00 21.71  ? 424 SER B CA  1 
ATOM   6966  C C   . SER B 1 424 ? 128.242 140.473 143.418 1.00 21.71  ? 424 SER B C   1 
ATOM   6967  O O   . SER B 1 424 ? 127.969 140.902 144.552 1.00 21.71  ? 424 SER B O   1 
ATOM   6968  C CB  . SER B 1 424 ? 126.780 141.003 141.446 1.00 21.71  ? 424 SER B CB  1 
ATOM   6969  O OG  . SER B 1 424 ? 126.631 141.791 140.280 1.00 21.71  ? 424 SER B OG  1 
ATOM   6970  N N   . TYR B 1 425 ? 128.706 139.235 143.214 1.00 22.64  ? 425 TYR B N   1 
ATOM   6971  C CA  . TYR B 1 425 ? 128.965 138.363 144.358 1.00 22.64  ? 425 TYR B CA  1 
ATOM   6972  C C   . TYR B 1 425 ? 130.018 138.965 145.282 1.00 22.64  ? 425 TYR B C   1 
ATOM   6973  O O   . TYR B 1 425 ? 129.872 138.934 146.516 1.00 22.64  ? 425 TYR B O   1 
ATOM   6974  C CB  . TYR B 1 425 ? 129.404 136.979 143.879 1.00 22.64  ? 425 TYR B CB  1 
ATOM   6975  C CG  . TYR B 1 425 ? 129.844 136.059 144.997 1.00 22.64  ? 425 TYR B CG  1 
ATOM   6976  C CD1 . TYR B 1 425 ? 128.925 135.279 145.683 1.00 22.64  ? 425 TYR B CD1 1 
ATOM   6977  C CD2 . TYR B 1 425 ? 131.181 135.971 145.367 1.00 22.64  ? 425 TYR B CD2 1 
ATOM   6978  C CE1 . TYR B 1 425 ? 129.322 134.442 146.706 1.00 22.64  ? 425 TYR B CE1 1 
ATOM   6979  C CE2 . TYR B 1 425 ? 131.585 135.140 146.388 1.00 22.64  ? 425 TYR B CE2 1 
ATOM   6980  C CZ  . TYR B 1 425 ? 130.653 134.376 147.053 1.00 22.64  ? 425 TYR B CZ  1 
ATOM   6981  O OH  . TYR B 1 425 ? 131.054 133.543 148.070 1.00 22.64  ? 425 TYR B OH  1 
ATOM   6982  N N   . ASN B 1 426 ? 131.092 139.510 144.701 1.00 23.21  ? 426 ASN B N   1 
ATOM   6983  C CA  . ASN B 1 426 ? 132.141 140.123 145.511 1.00 23.21  ? 426 ASN B CA  1 
ATOM   6984  C C   . ASN B 1 426 ? 131.582 141.248 146.372 1.00 23.21  ? 426 ASN B C   1 
ATOM   6985  O O   . ASN B 1 426 ? 131.870 141.331 147.574 1.00 23.21  ? 426 ASN B O   1 
ATOM   6986  C CB  . ASN B 1 426 ? 133.260 140.645 144.609 1.00 23.21  ? 426 ASN B CB  1 
ATOM   6987  C CG  . ASN B 1 426 ? 134.206 139.553 144.162 1.00 23.21  ? 426 ASN B CG  1 
ATOM   6988  O OD1 . ASN B 1 426 ? 134.200 138.450 144.704 1.00 23.21  ? 426 ASN B OD1 1 
ATOM   6989  N ND2 . ASN B 1 426 ? 135.029 139.857 143.167 1.00 23.21  ? 426 ASN B ND2 1 
ATOM   6990  N N   . ALA B 1 427 ? 130.771 142.123 145.771 1.00 25.50  ? 427 ALA B N   1 
ATOM   6991  C CA  . ALA B 1 427 ? 130.213 143.253 146.511 1.00 25.50  ? 427 ALA B CA  1 
ATOM   6992  C C   . ALA B 1 427 ? 129.339 142.781 147.668 1.00 25.50  ? 427 ALA B C   1 
ATOM   6993  O O   . ALA B 1 427 ? 129.449 143.288 148.794 1.00 25.50  ? 427 ALA B O   1 
ATOM   6994  C CB  . ALA B 1 427 ? 129.416 144.152 145.566 1.00 25.50  ? 427 ALA B CB  1 
ATOM   6995  N N   . GLU B 1 428 ? 128.465 141.803 147.408 1.00 29.84  ? 428 GLU B N   1 
ATOM   6996  C CA  . GLU B 1 428 ? 127.573 141.318 148.460 1.00 29.84  ? 428 GLU B CA  1 
ATOM   6997  C C   . GLU B 1 428 ? 128.360 140.741 149.634 1.00 29.84  ? 428 GLU B C   1 
ATOM   6998  O O   . GLU B 1 428 ? 128.110 141.084 150.804 1.00 29.84  ? 428 GLU B O   1 
ATOM   6999  C CB  . GLU B 1 428 ? 126.616 140.274 147.884 1.00 29.84  ? 428 GLU B CB  1 
ATOM   7000  C CG  . GLU B 1 428 ? 125.595 139.751 148.874 1.00 29.84  ? 428 GLU B CG  1 
ATOM   7001  C CD  . GLU B 1 428 ? 124.278 140.494 148.796 1.00 29.84  ? 428 GLU B CD  1 
ATOM   7002  O OE1 . GLU B 1 428 ? 124.020 141.143 147.762 1.00 29.84  ? 428 GLU B OE1 1 
ATOM   7003  O OE2 . GLU B 1 428 ? 123.500 140.429 149.769 1.00 29.84  ? 428 GLU B OE2 1 
ATOM   7004  N N   . LEU B 1 429 ? 129.328 139.866 149.338 1.00 29.41  ? 429 LEU B N   1 
ATOM   7005  C CA  . LEU B 1 429 ? 130.099 139.244 150.411 1.00 29.41  ? 429 LEU B CA  1 
ATOM   7006  C C   . LEU B 1 429 ? 130.883 140.283 151.203 1.00 29.41  ? 429 LEU B C   1 
ATOM   7007  O O   . LEU B 1 429 ? 130.954 140.212 152.439 1.00 29.41  ? 429 LEU B O   1 
ATOM   7008  C CB  . LEU B 1 429 ? 131.037 138.182 149.839 1.00 29.41  ? 429 LEU B CB  1 
ATOM   7009  C CG  . LEU B 1 429 ? 131.922 137.463 150.859 1.00 29.41  ? 429 LEU B CG  1 
ATOM   7010  C CD1 . LEU B 1 429 ? 131.094 136.529 151.726 1.00 29.41  ? 429 LEU B CD1 1 
ATOM   7011  C CD2 . LEU B 1 429 ? 133.043 136.705 150.171 1.00 29.41  ? 429 LEU B CD2 1 
ATOM   7012  N N   . LEU B 1 430 ? 131.476 141.260 150.509 1.00 29.63  ? 430 LEU B N   1 
ATOM   7013  C CA  . LEU B 1 430 ? 132.247 142.290 151.196 1.00 29.63  ? 430 LEU B CA  1 
ATOM   7014  C C   . LEU B 1 430 ? 131.372 143.086 152.155 1.00 29.63  ? 430 LEU B C   1 
ATOM   7015  O O   . LEU B 1 430 ? 131.760 143.339 153.303 1.00 29.63  ? 430 LEU B O   1 
ATOM   7016  C CB  . LEU B 1 430 ? 132.904 143.216 150.173 1.00 29.63  ? 430 LEU B CB  1 
ATOM   7017  C CG  . LEU B 1 430 ? 133.681 144.402 150.743 1.00 29.63  ? 430 LEU B CG  1 
ATOM   7018  C CD1 . LEU B 1 430 ? 134.889 143.914 151.519 1.00 29.63  ? 430 LEU B CD1 1 
ATOM   7019  C CD2 . LEU B 1 430 ? 134.097 145.350 149.633 1.00 29.63  ? 430 LEU B CD2 1 
ATOM   7020  N N   . VAL B 1 431 ? 130.180 143.486 151.701 1.00 30.03  ? 431 VAL B N   1 
ATOM   7021  C CA  . VAL B 1 431 ? 129.297 144.266 152.566 1.00 30.03  ? 431 VAL B CA  1 
ATOM   7022  C C   . VAL B 1 431 ? 128.924 143.467 153.809 1.00 30.03  ? 431 VAL B C   1 
ATOM   7023  O O   . VAL B 1 431 ? 128.962 143.986 154.936 1.00 30.03  ? 431 VAL B O   1 
ATOM   7024  C CB  . VAL B 1 431 ? 128.049 144.726 151.789 1.00 30.03  ? 431 VAL B CB  1 
ATOM   7025  C CG1 . VAL B 1 431 ? 127.066 145.406 152.722 1.00 30.03  ? 431 VAL B CG1 1 
ATOM   7026  C CG2 . VAL B 1 431 ? 128.444 145.668 150.668 1.00 30.03  ? 431 VAL B CG2 1 
ATOM   7027  N N   . ALA B 1 432 ? 128.569 142.189 153.628 1.00 32.69  ? 432 ALA B N   1 
ATOM   7028  C CA  . ALA B 1 432 ? 128.168 141.377 154.777 1.00 32.69  ? 432 ALA B CA  1 
ATOM   7029  C C   . ALA B 1 432 ? 129.305 141.241 155.788 1.00 32.69  ? 432 ALA B C   1 
ATOM   7030  O O   . ALA B 1 432 ? 129.103 141.406 157.002 1.00 32.69  ? 432 ALA B O   1 
ATOM   7031  C CB  . ALA B 1 432 ? 127.695 140.003 154.306 1.00 32.69  ? 432 ALA B CB  1 
ATOM   7032  N N   . LEU B 1 433 ? 130.517 140.951 155.301 1.00 34.77  ? 433 LEU B N   1 
ATOM   7033  C CA  . LEU B 1 433 ? 131.652 140.778 156.204 1.00 34.77  ? 433 LEU B CA  1 
ATOM   7034  C C   . LEU B 1 433 ? 131.962 142.063 156.963 1.00 34.77  ? 433 LEU B C   1 
ATOM   7035  O O   . LEU B 1 433 ? 132.230 142.033 158.174 1.00 34.77  ? 433 LEU B O   1 
ATOM   7036  C CB  . LEU B 1 433 ? 132.880 140.316 155.420 1.00 34.77  ? 433 LEU B CB  1 
ATOM   7037  C CG  . LEU B 1 433 ? 133.085 138.812 155.247 1.00 34.77  ? 433 LEU B CG  1 
ATOM   7038  C CD1 . LEU B 1 433 ? 134.289 138.548 154.360 1.00 34.77  ? 433 LEU B CD1 1 
ATOM   7039  C CD2 . LEU B 1 433 ? 133.251 138.129 156.594 1.00 34.77  ? 433 LEU B CD2 1 
ATOM   7040  N N   . GLU B 1 434 ? 131.936 143.203 156.266 1.00 37.93  ? 434 GLU B N   1 
ATOM   7041  C CA  . GLU B 1 434 ? 132.236 144.470 156.924 1.00 37.93  ? 434 GLU B CA  1 
ATOM   7042  C C   . GLU B 1 434 ? 131.211 144.790 158.005 1.00 37.93  ? 434 GLU B C   1 
ATOM   7043  O O   . GLU B 1 434 ? 131.573 145.258 159.093 1.00 37.93  ? 434 GLU B O   1 
ATOM   7044  C CB  . GLU B 1 434 ? 132.303 145.592 155.890 1.00 37.93  ? 434 GLU B CB  1 
ATOM   7045  C CG  . GLU B 1 434 ? 133.433 145.431 154.890 1.00 37.93  ? 434 GLU B CG  1 
ATOM   7046  C CD  . GLU B 1 434 ? 134.707 146.111 155.332 1.00 37.93  ? 434 GLU B CD  1 
ATOM   7047  O OE1 . GLU B 1 434 ? 134.694 147.350 155.475 1.00 37.93  ? 434 GLU B OE1 1 
ATOM   7048  O OE2 . GLU B 1 434 ? 135.720 145.411 155.539 1.00 37.93  ? 434 GLU B OE2 1 
ATOM   7049  N N   . ASN B 1 435 ? 129.926 144.545 157.728 1.00 36.46  ? 435 ASN B N   1 
ATOM   7050  C CA  . ASN B 1 435 ? 128.907 144.797 158.744 1.00 36.46  ? 435 ASN B CA  1 
ATOM   7051  C C   . ASN B 1 435 ? 129.122 143.920 159.972 1.00 36.46  ? 435 ASN B C   1 
ATOM   7052  O O   . ASN B 1 435 ? 129.031 144.397 161.117 1.00 36.46  ? 435 ASN B O   1 
ATOM   7053  C CB  . ASN B 1 435 ? 127.514 144.565 158.160 1.00 36.46  ? 435 ASN B CB  1 
ATOM   7054  C CG  . ASN B 1 435 ? 127.094 145.662 157.210 1.00 36.46  ? 435 ASN B CG  1 
ATOM   7055  O OD1 . ASN B 1 435 ? 127.724 146.715 157.143 1.00 36.46  ? 435 ASN B OD1 1 
ATOM   7056  N ND2 . ASN B 1 435 ? 126.021 145.422 156.468 1.00 36.46  ? 435 ASN B ND2 1 
ATOM   7057  N N   . GLN B 1 436 ? 129.417 142.634 159.753 1.00 40.53  ? 436 GLN B N   1 
ATOM   7058  C CA  . GLN B 1 436 ? 129.662 141.733 160.876 1.00 40.53  ? 436 GLN B CA  1 
ATOM   7059  C C   . GLN B 1 436 ? 130.821 142.228 161.734 1.00 40.53  ? 436 GLN B C   1 
ATOM   7060  O O   . GLN B 1 436 ? 130.725 142.277 162.970 1.00 40.53  ? 436 GLN B O   1 
ATOM   7061  C CB  . GLN B 1 436 ? 129.939 140.321 160.359 1.00 40.53  ? 436 GLN B CB  1 
ATOM   7062  C CG  . GLN B 1 436 ? 130.349 139.336 161.437 1.00 40.53  ? 436 GLN B CG  1 
ATOM   7063  C CD  . GLN B 1 436 ? 129.163 138.654 162.083 1.00 40.53  ? 436 GLN B CD  1 
ATOM   7064  O OE1 . GLN B 1 436 ? 128.075 138.606 161.513 1.00 40.53  ? 436 GLN B OE1 1 
ATOM   7065  N NE2 . GLN B 1 436 ? 129.366 138.127 163.283 1.00 40.53  ? 436 GLN B NE2 1 
ATOM   7066  N N   . HIS B 1 437 ? 131.924 142.621 161.091 1.00 42.73  ? 437 HIS B N   1 
ATOM   7067  C CA  . HIS B 1 437 ? 133.088 143.056 161.856 1.00 42.73  ? 437 HIS B CA  1 
ATOM   7068  C C   . HIS B 1 437 ? 132.831 144.366 162.595 1.00 42.73  ? 437 HIS B C   1 
ATOM   7069  O O   . HIS B 1 437 ? 133.335 144.550 163.710 1.00 42.73  ? 437 HIS B O   1 
ATOM   7070  C CB  . HIS B 1 437 ? 134.306 143.177 160.942 1.00 42.73  ? 437 HIS B CB  1 
ATOM   7071  C CG  . HIS B 1 437 ? 134.991 141.871 160.682 1.00 42.73  ? 437 HIS B CG  1 
ATOM   7072  N ND1 . HIS B 1 437 ? 135.850 141.289 161.589 1.00 42.73  ? 437 HIS B ND1 1 
ATOM   7073  C CD2 . HIS B 1 437 ? 134.940 141.031 159.621 1.00 42.73  ? 437 HIS B CD2 1 
ATOM   7074  C CE1 . HIS B 1 437 ? 136.300 140.148 161.098 1.00 42.73  ? 437 HIS B CE1 1 
ATOM   7075  N NE2 . HIS B 1 437 ? 135.764 139.969 159.904 1.00 42.73  ? 437 HIS B NE2 1 
ATOM   7076  N N   . THR B 1 438 ? 132.055 145.280 162.007 1.00 43.23  ? 438 THR B N   1 
ATOM   7077  C CA  . THR B 1 438 ? 131.723 146.521 162.707 1.00 43.23  ? 438 THR B CA  1 
ATOM   7078  C C   . THR B 1 438 ? 130.922 146.241 163.976 1.00 43.23  ? 438 THR B C   1 
ATOM   7079  O O   . THR B 1 438 ? 131.216 146.788 165.052 1.00 43.23  ? 438 THR B O   1 
ATOM   7080  C CB  . THR B 1 438 ? 130.945 147.455 161.780 1.00 43.23  ? 438 THR B CB  1 
ATOM   7081  O OG1 . THR B 1 438 ? 131.783 147.857 160.690 1.00 43.23  ? 438 THR B OG1 1 
ATOM   7082  C CG2 . THR B 1 438 ? 130.477 148.689 162.533 1.00 43.23  ? 438 THR B CG2 1 
ATOM   7083  N N   . ILE B 1 439 ? 129.903 145.382 163.867 1.00 45.19  ? 439 ILE B N   1 
ATOM   7084  C CA  . ILE B 1 439 ? 129.114 145.032 165.047 1.00 45.19  ? 439 ILE B CA  1 
ATOM   7085  C C   . ILE B 1 439 ? 130.005 144.406 166.115 1.00 45.19  ? 439 ILE B C   1 
ATOM   7086  O O   . ILE B 1 439 ? 129.923 144.753 167.307 1.00 45.19  ? 439 ILE B O   1 
ATOM   7087  C CB  . ILE B 1 439 ? 127.955 144.097 164.657 1.00 45.19  ? 439 ILE B CB  1 
ATOM   7088  C CG1 . ILE B 1 439 ? 127.022 144.784 163.659 1.00 45.19  ? 439 ILE B CG1 1 
ATOM   7089  C CG2 . ILE B 1 439 ? 127.191 143.652 165.890 1.00 45.19  ? 439 ILE B CG2 1 
ATOM   7090  C CD1 . ILE B 1 439 ? 126.390 146.048 164.186 1.00 45.19  ? 439 ILE B CD1 1 
ATOM   7091  N N   . ASP B 1 440 ? 130.880 143.485 165.700 1.00 48.12  ? 440 ASP B N   1 
ATOM   7092  C CA  . ASP B 1 440 ? 131.764 142.823 166.653 1.00 48.12  ? 440 ASP B CA  1 
ATOM   7093  C C   . ASP B 1 440 ? 132.669 143.822 167.365 1.00 48.12  ? 440 ASP B C   1 
ATOM   7094  O O   . ASP B 1 440 ? 132.847 143.743 168.586 1.00 48.12  ? 440 ASP B O   1 
ATOM   7095  C CB  . ASP B 1 440 ? 132.599 141.759 165.942 1.00 48.12  ? 440 ASP B CB  1 
ATOM   7096  C CG  . ASP B 1 440 ? 131.875 140.434 165.823 1.00 48.12  ? 440 ASP B CG  1 
ATOM   7097  O OD1 . ASP B 1 440 ? 130.770 140.306 166.391 1.00 48.12  ? 440 ASP B OD1 1 
ATOM   7098  O OD2 . ASP B 1 440 ? 132.411 139.520 165.162 1.00 48.12  ? 440 ASP B OD2 1 
ATOM   7099  N N   . LEU B 1 441 ? 133.254 144.767 166.621 1.00 48.65  ? 441 LEU B N   1 
ATOM   7100  C CA  . LEU B 1 441 ? 134.191 145.698 167.246 1.00 48.65  ? 441 LEU B CA  1 
ATOM   7101  C C   . LEU B 1 441 ? 133.481 146.622 168.229 1.00 48.65  ? 441 LEU B C   1 
ATOM   7102  O O   . LEU B 1 441 ? 134.021 146.919 169.302 1.00 48.65  ? 441 LEU B O   1 
ATOM   7103  C CB  . LEU B 1 441 ? 134.953 146.500 166.185 1.00 48.65  ? 441 LEU B CB  1 
ATOM   7104  C CG  . LEU B 1 441 ? 134.306 147.551 165.278 1.00 48.65  ? 441 LEU B CG  1 
ATOM   7105  C CD1 . LEU B 1 441 ? 134.282 148.921 165.937 1.00 48.65  ? 441 LEU B CD1 1 
ATOM   7106  C CD2 . LEU B 1 441 ? 135.042 147.622 163.955 1.00 48.65  ? 441 LEU B CD2 1 
ATOM   7107  N N   . THR B 1 442 ? 132.271 147.083 167.893 1.00 51.09  ? 442 THR B N   1 
ATOM   7108  C CA  . THR B 1 442 ? 131.549 147.936 168.838 1.00 51.09  ? 442 THR B CA  1 
ATOM   7109  C C   . THR B 1 442 ? 131.211 147.183 170.123 1.00 51.09  ? 442 THR B C   1 
ATOM   7110  O O   . THR B 1 442 ? 131.397 147.710 171.236 1.00 51.09  ? 442 THR B O   1 
ATOM   7111  C CB  . THR B 1 442 ? 130.282 148.495 168.192 1.00 51.09  ? 442 THR B CB  1 
ATOM   7112  O OG1 . THR B 1 442 ? 129.429 147.416 167.790 1.00 51.09  ? 442 THR B OG1 1 
ATOM   7113  C CG2 . THR B 1 442 ? 130.632 149.346 166.983 1.00 51.09  ? 442 THR B CG2 1 
ATOM   7114  N N   . ASP B 1 443 ? 130.728 145.942 169.994 1.00 54.03  ? 443 ASP B N   1 
ATOM   7115  C CA  . ASP B 1 443 ? 130.419 145.160 171.189 1.00 54.03  ? 443 ASP B CA  1 
ATOM   7116  C C   . ASP B 1 443 ? 131.668 144.920 172.031 1.00 54.03  ? 443 ASP B C   1 
ATOM   7117  O O   . ASP B 1 443 ? 131.627 145.020 173.266 1.00 54.03  ? 443 ASP B O   1 
ATOM   7118  C CB  . ASP B 1 443 ? 129.769 143.833 170.797 1.00 54.03  ? 443 ASP B CB  1 
ATOM   7119  C CG  . ASP B 1 443 ? 128.312 143.990 170.413 1.00 54.03  ? 443 ASP B CG  1 
ATOM   7120  O OD1 . ASP B 1 443 ? 127.710 145.024 170.768 1.00 54.03  ? 443 ASP B OD1 1 
ATOM   7121  O OD2 . ASP B 1 443 ? 127.767 143.079 169.757 1.00 54.03  ? 443 ASP B OD2 1 
ATOM   7122  N N   . SER B 1 444 ? 132.792 144.611 171.377 1.00 55.08  ? 444 SER B N   1 
ATOM   7123  C CA  . SER B 1 444 ? 134.031 144.371 172.107 1.00 55.08  ? 444 SER B CA  1 
ATOM   7124  C C   . SER B 1 444 ? 134.497 145.625 172.834 1.00 55.08  ? 444 SER B C   1 
ATOM   7125  O O   . SER B 1 444 ? 135.009 145.543 173.954 1.00 55.08  ? 444 SER B O   1 
ATOM   7126  C CB  . SER B 1 444 ? 135.117 143.873 171.155 1.00 55.08  ? 444 SER B CB  1 
ATOM   7127  O OG  . SER B 1 444 ? 135.815 144.956 170.568 1.00 55.08  ? 444 SER B OG  1 
ATOM   7128  N N   . GLU B 1 445 ? 134.338 146.796 172.211 1.00 58.64  ? 445 GLU B N   1 
ATOM   7129  C CA  . GLU B 1 445 ? 134.731 148.039 172.869 1.00 58.64  ? 445 GLU B CA  1 
ATOM   7130  C C   . GLU B 1 445 ? 133.909 148.278 174.130 1.00 58.64  ? 445 GLU B C   1 
ATOM   7131  O O   . GLU B 1 445 ? 134.454 148.634 175.186 1.00 58.64  ? 445 GLU B O   1 
ATOM   7132  C CB  . GLU B 1 445 ? 134.586 149.212 171.900 1.00 58.64  ? 445 GLU B CB  1 
ATOM   7133  C CG  . GLU B 1 445 ? 135.601 150.322 172.112 1.00 58.64  ? 445 GLU B CG  1 
ATOM   7134  C CD  . GLU B 1 445 ? 137.013 149.894 171.769 1.00 58.64  ? 445 GLU B CD  1 
ATOM   7135  O OE1 . GLU B 1 445 ? 137.194 149.211 170.740 1.00 58.64  ? 445 GLU B OE1 1 
ATOM   7136  O OE2 . GLU B 1 445 ? 137.941 150.241 172.528 1.00 58.64  ? 445 GLU B OE2 1 
ATOM   7137  N N   . MET B 1 446 ? 132.589 148.081 174.041 1.00 60.97  ? 446 MET B N   1 
ATOM   7138  C CA  . MET B 1 446 ? 131.759 148.268 175.231 1.00 60.97  ? 446 MET B CA  1 
ATOM   7139  C C   . MET B 1 446 ? 132.147 147.289 176.337 1.00 60.97  ? 446 MET B C   1 
ATOM   7140  O O   . MET B 1 446 ? 132.263 147.672 177.514 1.00 60.97  ? 446 MET B O   1 
ATOM   7141  C CB  . MET B 1 446 ? 130.279 148.120 174.879 1.00 60.97  ? 446 MET B CB  1 
ATOM   7142  C CG  . MET B 1 446 ? 129.345 148.456 176.031 1.00 60.97  ? 446 MET B CG  1 
ATOM   7143  S SD  . MET B 1 446 ? 129.431 150.198 176.489 1.00 60.97  ? 446 MET B SD  1 
ATOM   7144  C CE  . MET B 1 446 ? 128.870 150.146 178.185 1.00 60.97  ? 446 MET B CE  1 
ATOM   7145  N N   . ASN B 1 447 ? 132.369 146.022 175.974 1.00 60.66  ? 447 ASN B N   1 
ATOM   7146  C CA  . ASN B 1 447 ? 132.737 145.027 176.976 1.00 60.66  ? 447 ASN B CA  1 
ATOM   7147  C C   . ASN B 1 447 ? 134.086 145.347 177.610 1.00 60.66  ? 447 ASN B C   1 
ATOM   7148  O O   . ASN B 1 447 ? 134.273 145.154 178.816 1.00 60.66  ? 447 ASN B O   1 
ATOM   7149  C CB  . ASN B 1 447 ? 132.749 143.632 176.353 1.00 60.66  ? 447 ASN B CB  1 
ATOM   7150  C CG  . ASN B 1 447 ? 131.404 142.941 176.453 1.00 60.66  ? 447 ASN B CG  1 
ATOM   7151  O OD1 . ASN B 1 447 ? 130.837 142.817 177.539 1.00 60.66  ? 447 ASN B OD1 1 
ATOM   7152  N ND2 . ASN B 1 447 ? 130.886 142.487 175.319 1.00 60.66  ? 447 ASN B ND2 1 
ATOM   7153  N N   . LYS B 1 448 ? 135.042 145.829 176.811 1.00 62.50  ? 448 LYS B N   1 
ATOM   7154  C CA  . LYS B 1 448 ? 136.350 146.189 177.350 1.00 62.50  ? 448 LYS B CA  1 
ATOM   7155  C C   . LYS B 1 448 ? 136.244 147.346 178.333 1.00 62.50  ? 448 LYS B C   1 
ATOM   7156  O O   . LYS B 1 448 ? 136.907 147.343 179.378 1.00 62.50  ? 448 LYS B O   1 
ATOM   7157  C CB  . LYS B 1 448 ? 137.309 146.544 176.215 1.00 62.50  ? 448 LYS B CB  1 
ATOM   7158  C CG  . LYS B 1 448 ? 137.865 145.346 175.472 1.00 62.50  ? 448 LYS B CG  1 
ATOM   7159  C CD  . LYS B 1 448 ? 139.040 145.746 174.601 1.00 62.50  ? 448 LYS B CD  1 
ATOM   7160  C CE  . LYS B 1 448 ? 138.581 146.518 173.378 1.00 62.50  ? 448 LYS B CE  1 
ATOM   7161  N NZ  . LYS B 1 448 ? 139.709 146.800 172.451 1.00 62.50  ? 448 LYS B NZ  1 
ATOM   7162  N N   . LEU B 1 449 ? 135.425 148.352 178.012 1.00 65.38  ? 449 LEU B N   1 
ATOM   7163  C CA  . LEU B 1 449 ? 135.237 149.451 178.955 1.00 65.38  ? 449 LEU B CA  1 
ATOM   7164  C C   . LEU B 1 449 ? 134.644 148.952 180.268 1.00 65.38  ? 449 LEU B C   1 
ATOM   7165  O O   . LEU B 1 449 ? 135.110 149.328 181.355 1.00 65.38  ? 449 LEU B O   1 
ATOM   7166  C CB  . LEU B 1 449 ? 134.349 150.533 178.343 1.00 65.38  ? 449 LEU B CB  1 
ATOM   7167  C CG  . LEU B 1 449 ? 134.110 151.757 179.231 1.00 65.38  ? 449 LEU B CG  1 
ATOM   7168  C CD1 . LEU B 1 449 ? 135.428 152.340 179.715 1.00 65.38  ? 449 LEU B CD1 1 
ATOM   7169  C CD2 . LEU B 1 449 ? 133.294 152.808 178.496 1.00 65.38  ? 449 LEU B CD2 1 
ATOM   7170  N N   . PHE B 1 450 ? 133.626 148.090 180.189 1.00 69.28  ? 450 PHE B N   1 
ATOM   7171  C CA  . PHE B 1 450 ? 133.029 147.563 181.415 1.00 69.28  ? 450 PHE B CA  1 
ATOM   7172  C C   . PHE B 1 450 ? 134.038 146.751 182.222 1.00 69.28  ? 450 PHE B C   1 
ATOM   7173  O O   . PHE B 1 450 ? 134.085 146.850 183.455 1.00 69.28  ? 450 PHE B O   1 
ATOM   7174  C CB  . PHE B 1 450 ? 131.800 146.717 181.090 1.00 69.28  ? 450 PHE B CB  1 
ATOM   7175  C CG  . PHE B 1 450 ? 131.085 146.200 182.305 1.00 69.28  ? 450 PHE B CG  1 
ATOM   7176  C CD1 . PHE B 1 450 ? 130.222 147.016 183.017 1.00 69.28  ? 450 PHE B CD1 1 
ATOM   7177  C CD2 . PHE B 1 450 ? 131.276 144.899 182.738 1.00 69.28  ? 450 PHE B CD2 1 
ATOM   7178  C CE1 . PHE B 1 450 ? 129.563 146.545 184.135 1.00 69.28  ? 450 PHE B CE1 1 
ATOM   7179  C CE2 . PHE B 1 450 ? 130.620 144.423 183.856 1.00 69.28  ? 450 PHE B CE2 1 
ATOM   7180  C CZ  . PHE B 1 450 ? 129.762 145.247 184.554 1.00 69.28  ? 450 PHE B CZ  1 
ATOM   7181  N N   . GLU B 1 451 ? 134.851 145.937 181.544 1.00 70.33  ? 451 GLU B N   1 
ATOM   7182  C CA  . GLU B 1 451 ? 135.824 145.110 182.250 1.00 70.33  ? 451 GLU B CA  1 
ATOM   7183  C C   . GLU B 1 451 ? 136.900 145.957 182.917 1.00 70.33  ? 451 GLU B C   1 
ATOM   7184  O O   . GLU B 1 451 ? 137.332 145.649 184.032 1.00 70.33  ? 451 GLU B O   1 
ATOM   7185  C CB  . GLU B 1 451 ? 136.448 144.096 181.294 1.00 70.33  ? 451 GLU B CB  1 
ATOM   7186  C CG  . GLU B 1 451 ? 135.620 142.834 181.128 1.00 70.33  ? 451 GLU B CG  1 
ATOM   7187  C CD  . GLU B 1 451 ? 135.259 142.196 182.457 1.00 70.33  ? 451 GLU B CD  1 
ATOM   7188  O OE1 . GLU B 1 451 ? 136.172 141.967 183.277 1.00 70.33  ? 451 GLU B OE1 1 
ATOM   7189  O OE2 . GLU B 1 451 ? 134.061 141.928 182.684 1.00 70.33  ? 451 GLU B OE2 1 
ATOM   7190  N N   . LYS B 1 452 ? 137.352 147.024 182.253 1.00 71.33  ? 452 LYS B N   1 
ATOM   7191  C CA  . LYS B 1 452 ? 138.318 147.917 182.887 1.00 71.33  ? 452 LYS B CA  1 
ATOM   7192  C C   . LYS B 1 452 ? 137.717 148.595 184.113 1.00 71.33  ? 452 LYS B C   1 
ATOM   7193  O O   . LYS B 1 452 ? 138.377 148.717 185.156 1.00 71.33  ? 452 LYS B O   1 
ATOM   7194  C CB  . LYS B 1 452 ? 138.816 148.958 181.887 1.00 71.33  ? 452 LYS B CB  1 
ATOM   7195  C CG  . LYS B 1 452 ? 139.972 149.795 182.405 1.00 71.33  ? 452 LYS B CG  1 
ATOM   7196  C CD  . LYS B 1 452 ? 140.539 150.697 181.324 1.00 71.33  ? 452 LYS B CD  1 
ATOM   7197  C CE  . LYS B 1 452 ? 139.661 151.914 181.102 1.00 71.33  ? 452 LYS B CE  1 
ATOM   7198  N NZ  . LYS B 1 452 ? 140.302 152.894 180.185 1.00 71.33  ? 452 LYS B NZ  1 
ATOM   7199  N N   . THR B 1 453 ? 136.459 149.039 184.009 1.00 72.89  ? 453 THR B N   1 
ATOM   7200  C CA  . THR B 1 453 ? 135.804 149.649 185.163 1.00 72.89  ? 453 THR B CA  1 
ATOM   7201  C C   . THR B 1 453 ? 135.708 148.663 186.323 1.00 72.89  ? 453 THR B C   1 
ATOM   7202  O O   . THR B 1 453 ? 135.934 149.033 187.481 1.00 72.89  ? 453 THR B O   1 
ATOM   7203  C CB  . THR B 1 453 ? 134.419 150.165 184.775 1.00 72.89  ? 453 THR B CB  1 
ATOM   7204  O OG1 . THR B 1 453 ? 134.557 151.280 183.885 1.00 72.89  ? 453 THR B OG1 1 
ATOM   7205  C CG2 . THR B 1 453 ? 133.648 150.610 186.008 1.00 72.89  ? 453 THR B CG2 1 
ATOM   7206  N N   . ARG B 1 454 ? 135.382 147.401 186.030 1.00 74.92  ? 454 ARG B N   1 
ATOM   7207  C CA  . ARG B 1 454 ? 135.388 146.379 187.075 1.00 74.92  ? 454 ARG B CA  1 
ATOM   7208  C C   . ARG B 1 454 ? 136.781 146.199 187.664 1.00 74.92  ? 454 ARG B C   1 
ATOM   7209  O O   . ARG B 1 454 ? 136.934 146.043 188.881 1.00 74.92  ? 454 ARG B O   1 
ATOM   7210  C CB  . ARG B 1 454 ? 134.877 145.048 186.527 1.00 74.92  ? 454 ARG B CB  1 
ATOM   7211  C CG  . ARG B 1 454 ? 134.955 143.910 187.538 1.00 74.92  ? 454 ARG B CG  1 
ATOM   7212  C CD  . ARG B 1 454 ? 134.365 142.621 186.995 1.00 74.92  ? 454 ARG B CD  1 
ATOM   7213  N NE  . ARG B 1 454 ? 132.914 142.696 186.876 1.00 74.92  ? 454 ARG B NE  1 
ATOM   7214  C CZ  . ARG B 1 454 ? 132.164 141.778 186.283 1.00 74.92  ? 454 ARG B CZ  1 
ATOM   7215  N NH1 . ARG B 1 454 ? 132.696 140.696 185.739 1.00 74.92  ? 454 ARG B NH1 1 
ATOM   7216  N NH2 . ARG B 1 454 ? 130.846 141.949 186.237 1.00 74.92  ? 454 ARG B NH2 1 
ATOM   7217  N N   . ARG B 1 455 ? 137.807 146.211 186.812 1.00 77.11  ? 455 ARG B N   1 
ATOM   7218  C CA  . ARG B 1 455 ? 139.170 145.983 187.277 1.00 77.11  ? 455 ARG B CA  1 
ATOM   7219  C C   . ARG B 1 455 ? 139.616 147.072 188.243 1.00 77.11  ? 455 ARG B C   1 
ATOM   7220  O O   . ARG B 1 455 ? 140.324 146.793 189.219 1.00 77.11  ? 455 ARG B O   1 
ATOM   7221  C CB  . ARG B 1 455 ? 140.121 145.902 186.084 1.00 77.11  ? 455 ARG B CB  1 
ATOM   7222  C CG  . ARG B 1 455 ? 141.494 145.363 186.425 1.00 77.11  ? 455 ARG B CG  1 
ATOM   7223  C CD  . ARG B 1 455 ? 142.141 144.696 185.223 1.00 77.11  ? 455 ARG B CD  1 
ATOM   7224  N NE  . ARG B 1 455 ? 142.405 145.646 184.149 1.00 77.11  ? 455 ARG B NE  1 
ATOM   7225  C CZ  . ARG B 1 455 ? 141.887 145.563 182.931 1.00 77.11  ? 455 ARG B CZ  1 
ATOM   7226  N NH1 . ARG B 1 455 ? 141.065 144.582 182.595 1.00 77.11  ? 455 ARG B NH1 1 
ATOM   7227  N NH2 . ARG B 1 455 ? 142.203 146.486 182.028 1.00 77.11  ? 455 ARG B NH2 1 
ATOM   7228  N N   . GLN B 1 456 ? 139.224 148.323 187.984 1.00 81.97  ? 456 GLN B N   1 
ATOM   7229  C CA  . GLN B 1 456 ? 139.617 149.410 188.879 1.00 81.97  ? 456 GLN B CA  1 
ATOM   7230  C C   . GLN B 1 456 ? 139.074 149.201 190.290 1.00 81.97  ? 456 GLN B C   1 
ATOM   7231  O O   . GLN B 1 456 ? 139.795 149.400 191.275 1.00 81.97  ? 456 GLN B O   1 
ATOM   7232  C CB  . GLN B 1 456 ? 139.150 150.752 188.320 1.00 81.97  ? 456 GLN B CB  1 
ATOM   7233  C CG  . GLN B 1 456 ? 140.113 151.374 187.327 1.00 81.97  ? 456 GLN B CG  1 
ATOM   7234  C CD  . GLN B 1 456 ? 139.859 152.852 187.123 1.00 81.97  ? 456 GLN B CD  1 
ATOM   7235  O OE1 . GLN B 1 456 ? 139.721 153.320 185.994 1.00 81.97  ? 456 GLN B OE1 1 
ATOM   7236  N NE2 . GLN B 1 456 ? 139.795 153.597 188.219 1.00 81.97  ? 456 GLN B NE2 1 
ATOM   7237  N N   . LEU B 1 457 ? 137.808 148.802 190.410 1.00 85.74  ? 457 LEU B N   1 
ATOM   7238  C CA  . LEU B 1 457 ? 137.183 148.552 191.710 1.00 85.74  ? 457 LEU B CA  1 
ATOM   7239  C C   . LEU B 1 457 ? 137.383 147.082 192.056 1.00 85.74  ? 457 LEU B C   1 
ATOM   7240  O O   . LEU B 1 457 ? 136.616 146.212 191.642 1.00 85.74  ? 457 LEU B O   1 
ATOM   7241  C CB  . LEU B 1 457 ? 135.706 148.925 191.679 1.00 85.74  ? 457 LEU B CB  1 
ATOM   7242  C CG  . LEU B 1 457 ? 135.360 150.374 191.338 1.00 85.74  ? 457 LEU B CG  1 
ATOM   7243  C CD1 . LEU B 1 457 ? 134.000 150.451 190.666 1.00 85.74  ? 457 LEU B CD1 1 
ATOM   7244  C CD2 . LEU B 1 457 ? 135.389 151.236 192.586 1.00 85.74  ? 457 LEU B CD2 1 
ATOM   7245  N N   . ARG B 1 458 ? 138.423 146.799 192.841 1.00 90.50  ? 458 ARG B N   1 
ATOM   7246  C CA  . ARG B 1 458 ? 138.808 145.413 193.089 1.00 90.50  ? 458 ARG B CA  1 
ATOM   7247  C C   . ARG B 1 458 ? 137.851 144.731 194.060 1.00 90.50  ? 458 ARG B C   1 
ATOM   7248  O O   . ARG B 1 458 ? 137.196 143.741 193.713 1.00 90.50  ? 458 ARG B O   1 
ATOM   7249  C CB  . ARG B 1 458 ? 140.246 145.354 193.607 1.00 90.50  ? 458 ARG B CB  1 
ATOM   7250  C CG  . ARG B 1 458 ? 141.288 145.467 192.508 1.00 90.50  ? 458 ARG B CG  1 
ATOM   7251  C CD  . ARG B 1 458 ? 142.695 145.522 193.072 1.00 90.50  ? 458 ARG B CD  1 
ATOM   7252  N NE  . ARG B 1 458 ? 142.854 144.663 194.238 1.00 90.50  ? 458 ARG B NE  1 
ATOM   7253  C CZ  . ARG B 1 458 ? 144.015 144.410 194.826 1.00 90.50  ? 458 ARG B CZ  1 
ATOM   7254  N NH1 . ARG B 1 458 ? 145.145 144.924 194.371 1.00 90.50  ? 458 ARG B NH1 1 
ATOM   7255  N NH2 . ARG B 1 458 ? 144.042 143.622 195.897 1.00 90.50  ? 458 ARG B NH2 1 
ATOM   7256  N N   . GLU B 1 459 ? 137.755 145.243 195.289 1.00 95.56  ? 459 GLU B N   1 
ATOM   7257  C CA  . GLU B 1 459 ? 136.949 144.600 196.320 1.00 95.56  ? 459 GLU B CA  1 
ATOM   7258  C C   . GLU B 1 459 ? 135.970 145.577 196.967 1.00 95.56  ? 459 GLU B C   1 
ATOM   7259  O O   . GLU B 1 459 ? 135.282 145.216 197.928 1.00 95.56  ? 459 GLU B O   1 
ATOM   7260  C CB  . GLU B 1 459 ? 137.855 143.962 197.379 1.00 95.56  ? 459 GLU B CB  1 
ATOM   7261  C CG  . GLU B 1 459 ? 137.194 142.890 198.236 1.00 95.56  ? 459 GLU B CG  1 
ATOM   7262  C CD  . GLU B 1 459 ? 136.797 141.663 197.438 1.00 95.56  ? 459 GLU B CD  1 
ATOM   7263  O OE1 . GLU B 1 459 ? 137.480 141.355 196.438 1.00 95.56  ? 459 GLU B OE1 1 
ATOM   7264  O OE2 . GLU B 1 459 ? 135.801 141.007 197.808 1.00 95.56  ? 459 GLU B OE2 1 
ATOM   7265  N N   . ASN B 1 460 ? 135.877 146.801 196.453 1.00 96.92  ? 460 ASN B N   1 
ATOM   7266  C CA  . ASN B 1 460 ? 135.028 147.817 197.058 1.00 96.92  ? 460 ASN B CA  1 
ATOM   7267  C C   . ASN B 1 460 ? 133.621 147.853 196.477 1.00 96.92  ? 460 ASN B C   1 
ATOM   7268  O O   . ASN B 1 460 ? 132.789 148.626 196.965 1.00 96.92  ? 460 ASN B O   1 
ATOM   7269  C CB  . ASN B 1 460 ? 135.672 149.198 196.904 1.00 96.92  ? 460 ASN B CB  1 
ATOM   7270  C CG  . ASN B 1 460 ? 137.116 149.219 197.356 1.00 96.92  ? 460 ASN B CG  1 
ATOM   7271  O OD1 . ASN B 1 460 ? 138.024 149.413 196.552 1.00 96.92  ? 460 ASN B OD1 1 
ATOM   7272  N ND2 . ASN B 1 460 ? 137.337 149.016 198.648 1.00 96.92  ? 460 ASN B ND2 1 
ATOM   7273  N N   . ALA B 1 461 ? 133.332 147.044 195.461 1.00 94.79  ? 461 ALA B N   1 
ATOM   7274  C CA  . ALA B 1 461 ? 132.010 147.038 194.852 1.00 94.79  ? 461 ALA B CA  1 
ATOM   7275  C C   . ALA B 1 461 ? 131.792 145.706 194.153 1.00 94.79  ? 461 ALA B C   1 
ATOM   7276  O O   . ALA B 1 461 ? 132.743 144.991 193.829 1.00 94.79  ? 461 ALA B O   1 
ATOM   7277  C CB  . ALA B 1 461 ? 131.841 148.198 193.865 1.00 94.79  ? 461 ALA B CB  1 
ATOM   7278  N N   . GLU B 1 462 ? 130.521 145.383 193.926 1.00 91.49  ? 462 GLU B N   1 
ATOM   7279  C CA  . GLU B 1 462 ? 130.132 144.179 193.208 1.00 91.49  ? 462 GLU B CA  1 
ATOM   7280  C C   . GLU B 1 462 ? 129.079 144.526 192.167 1.00 91.49  ? 462 GLU B C   1 
ATOM   7281  O O   . GLU B 1 462 ? 128.206 145.366 192.407 1.00 91.49  ? 462 GLU B O   1 
ATOM   7282  C CB  . GLU B 1 462 ? 129.598 143.104 194.164 1.00 91.49  ? 462 GLU B CB  1 
ATOM   7283  C CG  . GLU B 1 462 ? 128.600 143.613 195.187 1.00 91.49  ? 462 GLU B CG  1 
ATOM   7284  C CD  . GLU B 1 462 ? 128.351 142.616 196.302 1.00 91.49  ? 462 GLU B CD  1 
ATOM   7285  O OE1 . GLU B 1 462 ? 127.482 142.883 197.158 1.00 91.49  ? 462 GLU B OE1 1 
ATOM   7286  O OE2 . GLU B 1 462 ? 129.024 141.563 196.324 1.00 91.49  ? 462 GLU B OE2 1 
ATOM   7287  N N   . ASP B 1 463 ? 129.168 143.874 191.010 1.00 85.61  ? 463 ASP B N   1 
ATOM   7288  C CA  . ASP B 1 463 ? 128.249 144.148 189.913 1.00 85.61  ? 463 ASP B CA  1 
ATOM   7289  C C   . ASP B 1 463 ? 126.843 143.669 190.255 1.00 85.61  ? 463 ASP B C   1 
ATOM   7290  O O   . ASP B 1 463 ? 126.662 142.568 190.785 1.00 85.61  ? 463 ASP B O   1 
ATOM   7291  C CB  . ASP B 1 463 ? 128.744 143.473 188.635 1.00 85.61  ? 463 ASP B CB  1 
ATOM   7292  C CG  . ASP B 1 463 ? 127.688 143.432 187.549 1.00 85.61  ? 463 ASP B CG  1 
ATOM   7293  N N   . MET B 1 464 ? 125.845 144.497 189.948 1.00 83.38  ? 464 MET B N   1 
ATOM   7294  C CA  . MET B 1 464 ? 124.451 144.142 190.182 1.00 83.38  ? 464 MET B CA  1 
ATOM   7295  C C   . MET B 1 464 ? 123.842 143.326 189.050 1.00 83.38  ? 464 MET B C   1 
ATOM   7296  O O   . MET B 1 464 ? 122.728 142.815 189.208 1.00 83.38  ? 464 MET B O   1 
ATOM   7297  C CB  . MET B 1 464 ? 123.606 145.401 190.401 1.00 83.38  ? 464 MET B CB  1 
ATOM   7298  C CG  . MET B 1 464 ? 123.937 146.162 191.667 1.00 83.38  ? 464 MET B CG  1 
ATOM   7299  S SD  . MET B 1 464 ? 122.863 147.590 191.896 1.00 83.38  ? 464 MET B SD  1 
ATOM   7300  C CE  . MET B 1 464 ? 123.524 148.706 190.666 1.00 83.38  ? 464 MET B CE  1 
ATOM   7301  N N   . GLY B 1 465 ? 124.532 143.194 187.920 1.00 80.83  ? 465 GLY B N   1 
ATOM   7302  C CA  . GLY B 1 465 ? 124.063 142.377 186.826 1.00 80.83  ? 465 GLY B CA  1 
ATOM   7303  C C   . GLY B 1 465 ? 123.395 143.119 185.689 1.00 80.83  ? 465 GLY B C   1 
ATOM   7304  O O   . GLY B 1 465 ? 123.240 142.544 184.605 1.00 80.83  ? 465 GLY B O   1 
ATOM   7305  N N   . ASN B 1 466 ? 122.997 144.374 185.891 1.00 77.66  ? 466 ASN B N   1 
ATOM   7306  C CA  . ASN B 1 466 ? 122.366 145.168 184.844 1.00 77.66  ? 466 ASN B CA  1 
ATOM   7307  C C   . ASN B 1 466 ? 123.360 146.091 184.149 1.00 77.66  ? 466 ASN B C   1 
ATOM   7308  O O   . ASN B 1 466 ? 122.967 147.125 183.599 1.00 77.66  ? 466 ASN B O   1 
ATOM   7309  C CB  . ASN B 1 466 ? 121.202 145.976 185.417 1.00 77.66  ? 466 ASN B CB  1 
ATOM   7310  C CG  . ASN B 1 466 ? 121.601 146.797 186.626 1.00 77.66  ? 466 ASN B CG  1 
ATOM   7311  O OD1 . ASN B 1 466 ? 122.696 146.639 187.163 1.00 77.66  ? 466 ASN B OD1 1 
ATOM   7312  N ND2 . ASN B 1 466 ? 120.710 147.679 187.061 1.00 77.66  ? 466 ASN B ND2 1 
ATOM   7313  N N   . GLY B 1 467 ? 124.641 145.733 184.160 1.00 75.70  ? 467 GLY B N   1 
ATOM   7314  C CA  . GLY B 1 467 ? 125.664 146.606 183.624 1.00 75.70  ? 467 GLY B CA  1 
ATOM   7315  C C   . GLY B 1 467 ? 126.071 147.729 184.546 1.00 75.70  ? 467 GLY B C   1 
ATOM   7316  O O   . GLY B 1 467 ? 126.648 148.717 184.083 1.00 75.70  ? 467 GLY B O   1 
ATOM   7317  N N   . CYS B 1 468 ? 125.791 147.608 185.841 1.00 78.21  ? 468 CYS B N   1 
ATOM   7318  C CA  . CYS B 1 468 ? 126.041 148.671 186.801 1.00 78.21  ? 468 CYS B CA  1 
ATOM   7319  C C   . CYS B 1 468 ? 126.810 148.136 187.998 1.00 78.21  ? 468 CYS B C   1 
ATOM   7320  O O   . CYS B 1 468 ? 126.701 146.961 188.355 1.00 78.21  ? 468 CYS B O   1 
ATOM   7321  C CB  . CYS B 1 468 ? 124.735 149.308 187.288 1.00 78.21  ? 468 CYS B CB  1 
ATOM   7322  S SG  . CYS B 1 468 ? 123.789 150.157 186.016 1.00 78.21  ? 468 CYS B SG  1 
ATOM   7323  N N   . PHE B 1 469 ? 127.592 149.019 188.610 1.00 79.55  ? 469 PHE B N   1 
ATOM   7324  C CA  . PHE B 1 469 ? 128.257 148.755 189.876 1.00 79.55  ? 469 PHE B CA  1 
ATOM   7325  C C   . PHE B 1 469 ? 127.657 149.657 190.942 1.00 79.55  ? 469 PHE B C   1 
ATOM   7326  O O   . PHE B 1 469 ? 127.389 150.835 190.687 1.00 79.55  ? 469 PHE B O   1 
ATOM   7327  C CB  . PHE B 1 469 ? 129.762 149.017 189.783 1.00 79.55  ? 469 PHE B CB  1 
ATOM   7328  C CG  . PHE B 1 469 ? 130.479 148.119 188.826 1.00 79.55  ? 469 PHE B CG  1 
ATOM   7329  C CD1 . PHE B 1 469 ? 130.775 146.813 189.170 1.00 79.55  ? 469 PHE B CD1 1 
ATOM   7330  C CD2 . PHE B 1 469 ? 130.869 148.586 187.584 1.00 79.55  ? 469 PHE B CD2 1 
ATOM   7331  C CE1 . PHE B 1 469 ? 131.440 145.987 188.288 1.00 79.55  ? 469 PHE B CE1 1 
ATOM   7332  C CE2 . PHE B 1 469 ? 131.533 147.765 186.701 1.00 79.55  ? 469 PHE B CE2 1 
ATOM   7333  C CZ  . PHE B 1 469 ? 131.816 146.464 187.053 1.00 79.55  ? 469 PHE B CZ  1 
ATOM   7334  N N   . LYS B 1 470 ? 127.447 149.114 192.136 1.00 89.98  ? 470 LYS B N   1 
ATOM   7335  C CA  . LYS B 1 470 ? 127.047 149.921 193.278 1.00 89.98  ? 470 LYS B CA  1 
ATOM   7336  C C   . LYS B 1 470 ? 128.109 149.776 194.357 1.00 89.98  ? 470 LYS B C   1 
ATOM   7337  O O   . LYS B 1 470 ? 128.489 148.657 194.720 1.00 89.98  ? 470 LYS B O   1 
ATOM   7338  C CB  . LYS B 1 470 ? 125.639 149.543 193.770 1.00 89.98  ? 470 LYS B CB  1 
ATOM   7339  C CG  . LYS B 1 470 ? 125.432 148.158 194.365 1.00 89.98  ? 470 LYS B CG  1 
ATOM   7340  C CD  . LYS B 1 470 ? 125.581 148.181 195.876 1.00 89.98  ? 470 LYS B CD  1 
ATOM   7341  C CE  . LYS B 1 470 ? 125.246 146.834 196.485 1.00 89.98  ? 470 LYS B CE  1 
ATOM   7342  N NZ  . LYS B 1 470 ? 125.375 146.863 197.964 1.00 89.98  ? 470 LYS B NZ  1 
ATOM   7343  N N   . ILE B 1 471 ? 128.607 150.910 194.840 1.00 94.67  ? 471 ILE B N   1 
ATOM   7344  C CA  . ILE B 1 471 ? 129.809 150.970 195.660 1.00 94.67  ? 471 ILE B CA  1 
ATOM   7345  C C   . ILE B 1 471 ? 129.401 151.153 197.114 1.00 94.67  ? 471 ILE B C   1 
ATOM   7346  O O   . ILE B 1 471 ? 128.530 151.974 197.425 1.00 94.67  ? 471 ILE B O   1 
ATOM   7347  C CB  . ILE B 1 471 ? 130.736 152.104 195.194 1.00 94.67  ? 471 ILE B CB  1 
ATOM   7348  C CG1 . ILE B 1 471 ? 131.042 151.951 193.703 1.00 94.67  ? 471 ILE B CG1 1 
ATOM   7349  C CG2 . ILE B 1 471 ? 132.022 152.094 195.982 1.00 94.67  ? 471 ILE B CG2 1 
ATOM   7350  C CD1 . ILE B 1 471 ? 131.749 153.139 193.097 1.00 94.67  ? 471 ILE B CD1 1 
ATOM   7351  N N   . TYR B 1 472 ? 130.030 150.385 198.006 1.00 97.68  ? 472 TYR B N   1 
ATOM   7352  C CA  . TYR B 1 472 ? 129.596 150.339 199.398 1.00 97.68  ? 472 TYR B CA  1 
ATOM   7353  C C   . TYR B 1 472 ? 130.037 151.566 200.189 1.00 97.68  ? 472 TYR B C   1 
ATOM   7354  O O   . TYR B 1 472 ? 129.311 152.020 201.081 1.00 97.68  ? 472 TYR B O   1 
ATOM   7355  C CB  . TYR B 1 472 ? 130.115 149.061 200.055 1.00 97.68  ? 472 TYR B CB  1 
ATOM   7356  C CG  . TYR B 1 472 ? 129.315 147.835 199.684 1.00 97.68  ? 472 TYR B CG  1 
ATOM   7357  C CD1 . TYR B 1 472 ? 129.499 147.207 198.459 1.00 97.68  ? 472 TYR B CD1 1 
ATOM   7358  C CD2 . TYR B 1 472 ? 128.374 147.308 200.555 1.00 97.68  ? 472 TYR B CD2 1 
ATOM   7359  C CE1 . TYR B 1 472 ? 128.768 146.088 198.114 1.00 97.68  ? 472 TYR B CE1 1 
ATOM   7360  C CE2 . TYR B 1 472 ? 127.640 146.189 200.220 1.00 97.68  ? 472 TYR B CE2 1 
ATOM   7361  C CZ  . TYR B 1 472 ? 127.843 145.582 199.000 1.00 97.68  ? 472 TYR B CZ  1 
ATOM   7362  O OH  . TYR B 1 472 ? 127.109 144.469 198.665 1.00 97.68  ? 472 TYR B OH  1 
ATOM   7363  N N   . HIS B 1 473 ? 131.211 152.118 199.892 1.00 98.56  ? 473 HIS B N   1 
ATOM   7364  C CA  . HIS B 1 473 ? 131.672 153.282 200.631 1.00 98.56  ? 473 HIS B CA  1 
ATOM   7365  C C   . HIS B 1 473 ? 131.048 154.553 200.057 1.00 98.56  ? 473 HIS B C   1 
ATOM   7366  O O   . HIS B 1 473 ? 130.228 154.518 199.135 1.00 98.56  ? 473 HIS B O   1 
ATOM   7367  C CB  . HIS B 1 473 ? 133.198 153.356 200.624 1.00 98.56  ? 473 HIS B CB  1 
ATOM   7368  C CG  . HIS B 1 473 ? 133.793 153.569 199.267 1.00 98.56  ? 473 HIS B CG  1 
ATOM   7369  N ND1 . HIS B 1 473 ? 133.930 154.818 198.702 1.00 98.56  ? 473 HIS B ND1 1 
ATOM   7370  C CD2 . HIS B 1 473 ? 134.312 152.694 198.375 1.00 98.56  ? 473 HIS B CD2 1 
ATOM   7371  C CE1 . HIS B 1 473 ? 134.492 154.702 197.513 1.00 98.56  ? 473 HIS B CE1 1 
ATOM   7372  N NE2 . HIS B 1 473 ? 134.735 153.423 197.290 1.00 98.56  ? 473 HIS B NE2 1 
ATOM   7373  N N   . LYS B 1 474 ? 131.439 155.696 200.616 1.00 101.63 ? 474 LYS B N   1 
ATOM   7374  C CA  . LYS B 1 474 ? 130.901 156.990 200.208 1.00 101.63 ? 474 LYS B CA  1 
ATOM   7375  C C   . LYS B 1 474 ? 131.764 157.539 199.078 1.00 101.63 ? 474 LYS B C   1 
ATOM   7376  O O   . LYS B 1 474 ? 132.943 157.847 199.279 1.00 101.63 ? 474 LYS B O   1 
ATOM   7377  C CB  . LYS B 1 474 ? 130.859 157.951 201.393 1.00 101.63 ? 474 LYS B CB  1 
ATOM   7378  C CG  . LYS B 1 474 ? 130.127 159.251 201.113 1.00 101.63 ? 474 LYS B CG  1 
ATOM   7379  C CD  . LYS B 1 474 ? 130.083 160.133 202.349 1.00 101.63 ? 474 LYS B CD  1 
ATOM   7380  C CE  . LYS B 1 474 ? 129.192 159.528 203.423 1.00 101.63 ? 474 LYS B CE  1 
ATOM   7381  N NZ  . LYS B 1 474 ? 127.767 159.464 202.999 1.00 101.63 ? 474 LYS B NZ  1 
ATOM   7382  N N   . CYS B 1 475 ? 131.176 157.664 197.892 1.00 99.52  ? 475 CYS B N   1 
ATOM   7383  C CA  . CYS B 1 475 ? 131.899 158.031 196.677 1.00 99.52  ? 475 CYS B CA  1 
ATOM   7384  C C   . CYS B 1 475 ? 131.271 159.307 196.119 1.00 99.52  ? 475 CYS B C   1 
ATOM   7385  O O   . CYS B 1 475 ? 130.208 159.266 195.492 1.00 99.52  ? 475 CYS B O   1 
ATOM   7386  C CB  . CYS B 1 475 ? 131.857 156.879 195.674 1.00 99.52  ? 475 CYS B CB  1 
ATOM   7387  S SG  . CYS B 1 475 ? 132.933 157.028 194.226 1.00 99.52  ? 475 CYS B SG  1 
ATOM   7388  N N   . ASP B 1 476 ? 131.931 160.441 196.354 1.00 98.19  ? 476 ASP B N   1 
ATOM   7389  C CA  . ASP B 1 476 ? 131.431 161.745 195.943 1.00 98.19  ? 476 ASP B CA  1 
ATOM   7390  C C   . ASP B 1 476 ? 131.970 162.102 194.556 1.00 98.19  ? 476 ASP B C   1 
ATOM   7391  O O   . ASP B 1 476 ? 132.503 161.254 193.836 1.00 98.19  ? 476 ASP B O   1 
ATOM   7392  C CB  . ASP B 1 476 ? 131.792 162.800 196.988 1.00 98.19  ? 476 ASP B CB  1 
ATOM   7393  C CG  . ASP B 1 476 ? 133.285 163.043 197.081 1.00 98.19  ? 476 ASP B CG  1 
ATOM   7394  O OD1 . ASP B 1 476 ? 134.039 162.064 197.260 1.00 98.19  ? 476 ASP B OD1 1 
ATOM   7395  O OD2 . ASP B 1 476 ? 133.704 164.215 196.975 1.00 98.19  ? 476 ASP B OD2 1 
ATOM   7396  N N   . ASN B 1 477 ? 131.824 163.374 194.165 1.00 96.71  ? 477 ASN B N   1 
ATOM   7397  C CA  . ASN B 1 477 ? 132.210 163.790 192.817 1.00 96.71  ? 477 ASN B CA  1 
ATOM   7398  C C   . ASN B 1 477 ? 133.701 163.599 192.572 1.00 96.71  ? 477 ASN B C   1 
ATOM   7399  O O   . ASN B 1 477 ? 134.106 163.195 191.477 1.00 96.71  ? 477 ASN B O   1 
ATOM   7400  C CB  . ASN B 1 477 ? 131.820 165.247 192.574 1.00 96.71  ? 477 ASN B CB  1 
ATOM   7401  C CG  . ASN B 1 477 ? 130.323 165.459 192.573 1.00 96.71  ? 477 ASN B CG  1 
ATOM   7402  O OD1 . ASN B 1 477 ? 129.792 166.200 193.395 1.00 96.71  ? 477 ASN B OD1 1 
ATOM   7403  N ND2 . ASN B 1 477 ? 129.632 164.802 191.648 1.00 96.71  ? 477 ASN B ND2 1 
ATOM   7404  N N   . ALA B 1 478 ? 134.537 163.907 193.566 1.00 96.30  ? 478 ALA B N   1 
ATOM   7405  C CA  . ALA B 1 478 ? 135.966 163.643 193.424 1.00 96.30  ? 478 ALA B CA  1 
ATOM   7406  C C   . ALA B 1 478 ? 136.225 162.153 193.246 1.00 96.30  ? 478 ALA B C   1 
ATOM   7407  O O   . ALA B 1 478 ? 137.031 161.748 192.400 1.00 96.30  ? 478 ALA B O   1 
ATOM   7408  C CB  . ALA B 1 478 ? 136.725 164.182 194.635 1.00 96.30  ? 478 ALA B CB  1 
ATOM   7409  N N   . CYS B 1 479 ? 135.531 161.323 194.026 1.00 95.00  ? 479 CYS B N   1 
ATOM   7410  C CA  . CYS B 1 479 ? 135.641 159.874 193.891 1.00 95.00  ? 479 CYS B CA  1 
ATOM   7411  C C   . CYS B 1 479 ? 135.207 159.397 192.508 1.00 95.00  ? 479 CYS B C   1 
ATOM   7412  O O   . CYS B 1 479 ? 135.900 158.589 191.876 1.00 95.00  ? 479 CYS B O   1 
ATOM   7413  C CB  . CYS B 1 479 ? 134.802 159.212 194.981 1.00 95.00  ? 479 CYS B CB  1 
ATOM   7414  S SG  . CYS B 1 479 ? 134.778 157.421 194.980 1.00 95.00  ? 479 CYS B SG  1 
ATOM   7415  N N   . ILE B 1 480 ? 134.063 159.883 192.024 1.00 91.98  ? 480 ILE B N   1 
ATOM   7416  C CA  . ILE B 1 480 ? 133.560 159.445 190.724 1.00 91.98  ? 480 ILE B CA  1 
ATOM   7417  C C   . ILE B 1 480 ? 134.501 159.889 189.611 1.00 91.98  ? 480 ILE B C   1 
ATOM   7418  O O   . ILE B 1 480 ? 134.769 159.138 188.665 1.00 91.98  ? 480 ILE B O   1 
ATOM   7419  C CB  . ILE B 1 480 ? 132.129 159.968 190.506 1.00 91.98  ? 480 ILE B CB  1 
ATOM   7420  C CG1 . ILE B 1 480 ? 131.163 159.295 191.484 1.00 91.98  ? 480 ILE B CG1 1 
ATOM   7421  C CG2 . ILE B 1 480 ? 131.684 159.727 189.074 1.00 91.98  ? 480 ILE B CG2 1 
ATOM   7422  C CD1 . ILE B 1 480 ? 130.900 157.837 191.181 1.00 91.98  ? 480 ILE B CD1 1 
ATOM   7423  N N   . GLU B 1 481 ? 135.016 161.116 189.706 1.00 92.00  ? 481 GLU B N   1 
ATOM   7424  C CA  . GLU B 1 481 ? 135.959 161.606 188.708 1.00 92.00  ? 481 GLU B CA  1 
ATOM   7425  C C   . GLU B 1 481 ? 137.256 160.807 188.735 1.00 92.00  ? 481 GLU B C   1 
ATOM   7426  O O   . GLU B 1 481 ? 137.855 160.551 187.686 1.00 92.00  ? 481 GLU B O   1 
ATOM   7427  C CB  . GLU B 1 481 ? 136.232 163.093 188.934 1.00 92.00  ? 481 GLU B CB  1 
ATOM   7428  C CG  . GLU B 1 481 ? 137.086 163.741 187.857 1.00 92.00  ? 481 GLU B CG  1 
ATOM   7429  C CD  . GLU B 1 481 ? 137.734 165.030 188.323 1.00 92.00  ? 481 GLU B CD  1 
ATOM   7430  O OE1 . GLU B 1 481 ? 137.223 165.640 189.286 1.00 92.00  ? 481 GLU B OE1 1 
ATOM   7431  O OE2 . GLU B 1 481 ? 138.752 165.436 187.724 1.00 92.00  ? 481 GLU B OE2 1 
ATOM   7432  N N   . SER B 1 482 ? 137.711 160.412 189.927 1.00 92.25  ? 482 SER B N   1 
ATOM   7433  C CA  . SER B 1 482 ? 138.901 159.572 190.018 1.00 92.25  ? 482 SER B CA  1 
ATOM   7434  C C   . SER B 1 482 ? 138.660 158.209 189.383 1.00 92.25  ? 482 SER B C   1 
ATOM   7435  O O   . SER B 1 482 ? 139.551 157.655 188.727 1.00 92.25  ? 482 SER B O   1 
ATOM   7436  C CB  . SER B 1 482 ? 139.327 159.418 191.478 1.00 92.25  ? 482 SER B CB  1 
ATOM   7437  O OG  . SER B 1 482 ? 138.611 158.373 192.112 1.00 92.25  ? 482 SER B OG  1 
ATOM   7438  N N   . ILE B 1 483 ? 137.465 157.645 189.578 1.00 89.21  ? 483 ILE B N   1 
ATOM   7439  C CA  . ILE B 1 483 ? 137.133 156.378 188.928 1.00 89.21  ? 483 ILE B CA  1 
ATOM   7440  C C   . ILE B 1 483 ? 137.134 156.539 187.413 1.00 89.21  ? 483 ILE B C   1 
ATOM   7441  O O   . ILE B 1 483 ? 137.671 155.696 186.683 1.00 89.21  ? 483 ILE B O   1 
ATOM   7442  C CB  . ILE B 1 483 ? 135.781 155.844 189.437 1.00 89.21  ? 483 ILE B CB  1 
ATOM   7443  C CG1 . ILE B 1 483 ? 135.850 155.536 190.932 1.00 89.21  ? 483 ILE B CG1 1 
ATOM   7444  C CG2 . ILE B 1 483 ? 135.370 154.604 188.660 1.00 89.21  ? 483 ILE B CG2 1 
ATOM   7445  C CD1 . ILE B 1 483 ? 134.504 155.254 191.554 1.00 89.21  ? 483 ILE B CD1 1 
ATOM   7446  N N   . ARG B 1 484 ? 136.529 157.621 186.915 1.00 85.99  ? 484 ARG B N   1 
ATOM   7447  C CA  . ARG B 1 484 ? 136.461 157.834 185.472 1.00 85.99  ? 484 ARG B CA  1 
ATOM   7448  C C   . ARG B 1 484 ? 137.846 158.042 184.869 1.00 85.99  ? 484 ARG B C   1 
ATOM   7449  O O   . ARG B 1 484 ? 138.149 157.507 183.796 1.00 85.99  ? 484 ARG B O   1 
ATOM   7450  C CB  . ARG B 1 484 ? 135.561 159.027 185.156 1.00 85.99  ? 484 ARG B CB  1 
ATOM   7451  C CG  . ARG B 1 484 ? 134.089 158.796 185.437 1.00 85.99  ? 484 ARG B CG  1 
ATOM   7452  C CD  . ARG B 1 484 ? 133.285 160.054 185.164 1.00 85.99  ? 484 ARG B CD  1 
ATOM   7453  N NE  . ARG B 1 484 ? 131.869 159.877 185.459 1.00 85.99  ? 484 ARG B NE  1 
ATOM   7454  C CZ  . ARG B 1 484 ? 131.058 160.850 185.851 1.00 85.99  ? 484 ARG B CZ  1 
ATOM   7455  N NH1 . ARG B 1 484 ? 131.495 162.088 186.022 1.00 85.99  ? 484 ARG B NH1 1 
ATOM   7456  N NH2 . ARG B 1 484 ? 129.776 160.576 186.073 1.00 85.99  ? 484 ARG B NH2 1 
ATOM   7457  N N   . ASN B 1 485 ? 138.697 158.822 185.539 1.00 88.89  ? 485 ASN B N   1 
ATOM   7458  C CA  . ASN B 1 485 ? 140.030 159.094 185.009 1.00 88.89  ? 485 ASN B CA  1 
ATOM   7459  C C   . ASN B 1 485 ? 140.910 157.852 185.043 1.00 88.89  ? 485 ASN B C   1 
ATOM   7460  O O   . ASN B 1 485 ? 141.643 157.577 184.086 1.00 88.89  ? 485 ASN B O   1 
ATOM   7461  C CB  . ASN B 1 485 ? 140.685 160.232 185.792 1.00 88.89  ? 485 ASN B CB  1 
ATOM   7462  C CG  . ASN B 1 485 ? 139.936 161.541 185.656 1.00 88.89  ? 485 ASN B CG  1 
ATOM   7463  O OD1 . ASN B 1 485 ? 138.797 161.572 185.190 1.00 88.89  ? 485 ASN B OD1 1 
ATOM   7464  N ND2 . ASN B 1 485 ? 140.573 162.632 186.063 1.00 88.89  ? 485 ASN B ND2 1 
ATOM   7465  N N   . GLY B 1 486 ? 140.854 157.091 186.132 1.00 90.18  ? 486 GLY B N   1 
ATOM   7466  C CA  . GLY B 1 486 ? 141.698 155.930 186.306 1.00 90.18  ? 486 GLY B CA  1 
ATOM   7467  C C   . GLY B 1 486 ? 142.673 156.005 187.461 1.00 90.18  ? 486 GLY B C   1 
ATOM   7468  O O   . GLY B 1 486 ? 143.468 155.074 187.636 1.00 90.18  ? 486 GLY B O   1 
ATOM   7469  N N   . THR B 1 487 ? 142.641 157.076 188.254 1.00 92.72  ? 487 THR B N   1 
ATOM   7470  C CA  . THR B 1 487 ? 143.524 157.238 189.403 1.00 92.72  ? 487 THR B CA  1 
ATOM   7471  C C   . THR B 1 487 ? 142.832 156.886 190.715 1.00 92.72  ? 487 THR B C   1 
ATOM   7472  O O   . THR B 1 487 ? 143.213 157.392 191.776 1.00 92.72  ? 487 THR B O   1 
ATOM   7473  C CB  . THR B 1 487 ? 144.068 158.666 189.457 1.00 92.72  ? 487 THR B CB  1 
ATOM   7474  O OG1 . THR B 1 487 ? 142.982 159.588 189.603 1.00 92.72  ? 487 THR B OG1 1 
ATOM   7475  C CG2 . THR B 1 487 ? 144.833 158.990 188.183 1.00 92.72  ? 487 THR B CG2 1 
ATOM   7476  N N   . TYR B 1 488 ? 141.817 156.027 190.661 1.00 93.42  ? 488 TYR B N   1 
ATOM   7477  C CA  . TYR B 1 488 ? 141.119 155.602 191.866 1.00 93.42  ? 488 TYR B CA  1 
ATOM   7478  C C   . TYR B 1 488 ? 142.013 154.688 192.696 1.00 93.42  ? 488 TYR B C   1 
ATOM   7479  O O   . TYR B 1 488 ? 142.666 153.787 192.161 1.00 93.42  ? 488 TYR B O   1 
ATOM   7480  C CB  . TYR B 1 488 ? 139.820 154.888 191.493 1.00 93.42  ? 488 TYR B CB  1 
ATOM   7481  C CG  . TYR B 1 488 ? 139.073 154.286 192.662 1.00 93.42  ? 488 TYR B CG  1 
ATOM   7482  C CD1 . TYR B 1 488 ? 138.254 155.068 193.464 1.00 93.42  ? 488 TYR B CD1 1 
ATOM   7483  C CD2 . TYR B 1 488 ? 139.175 152.933 192.953 1.00 93.42  ? 488 TYR B CD2 1 
ATOM   7484  C CE1 . TYR B 1 488 ? 137.565 154.522 194.528 1.00 93.42  ? 488 TYR B CE1 1 
ATOM   7485  C CE2 . TYR B 1 488 ? 138.491 152.378 194.016 1.00 93.42  ? 488 TYR B CE2 1 
ATOM   7486  C CZ  . TYR B 1 488 ? 137.686 153.177 194.799 1.00 93.42  ? 488 TYR B CZ  1 
ATOM   7487  O OH  . TYR B 1 488 ? 137.001 152.629 195.859 1.00 93.42  ? 488 TYR B OH  1 
ATOM   7488  N N   . ASP B 1 489 ? 142.041 154.921 194.005 1.00 99.93  ? 489 ASP B N   1 
ATOM   7489  C CA  . ASP B 1 489 ? 142.838 154.130 194.934 1.00 99.93  ? 489 ASP B CA  1 
ATOM   7490  C C   . ASP B 1 489 ? 141.897 153.337 195.830 1.00 99.93  ? 489 ASP B C   1 
ATOM   7491  O O   . ASP B 1 489 ? 141.009 153.913 196.467 1.00 99.93  ? 489 ASP B O   1 
ATOM   7492  C CB  . ASP B 1 489 ? 143.757 155.023 195.767 1.00 99.93  ? 489 ASP B CB  1 
ATOM   7493  C CG  . ASP B 1 489 ? 144.863 154.244 196.451 1.00 99.93  ? 489 ASP B CG  1 
ATOM   7494  O OD1 . ASP B 1 489 ? 145.274 153.195 195.912 1.00 99.93  ? 489 ASP B OD1 1 
ATOM   7495  O OD2 . ASP B 1 489 ? 145.323 154.681 197.526 1.00 99.93  ? 489 ASP B OD2 1 
ATOM   7496  N N   . HIS B 1 490 ? 142.093 152.018 195.876 1.00 100.22 ? 490 HIS B N   1 
ATOM   7497  C CA  . HIS B 1 490 ? 141.179 151.154 196.614 1.00 100.22 ? 490 HIS B CA  1 
ATOM   7498  C C   . HIS B 1 490 ? 141.585 150.986 198.073 1.00 100.22 ? 490 HIS B C   1 
ATOM   7499  O O   . HIS B 1 490 ? 140.724 150.730 198.923 1.00 100.22 ? 490 HIS B O   1 
ATOM   7500  C CB  . HIS B 1 490 ? 141.090 149.786 195.934 1.00 100.22 ? 490 HIS B CB  1 
ATOM   7501  C CG  . HIS B 1 490 ? 142.332 148.961 196.067 1.00 100.22 ? 490 HIS B CG  1 
ATOM   7502  N ND1 . HIS B 1 490 ? 143.551 149.363 195.564 1.00 100.22 ? 490 HIS B ND1 1 
ATOM   7503  C CD2 . HIS B 1 490 ? 142.542 147.753 196.641 1.00 100.22 ? 490 HIS B CD2 1 
ATOM   7504  C CE1 . HIS B 1 490 ? 144.458 148.439 195.826 1.00 100.22 ? 490 HIS B CE1 1 
ATOM   7505  N NE2 . HIS B 1 490 ? 143.872 147.452 196.479 1.00 100.22 ? 490 HIS B NE2 1 
ATOM   7506  N N   . ASP B 1 491 ? 142.877 151.121 198.381 1.00 102.13 ? 491 ASP B N   1 
ATOM   7507  C CA  . ASP B 1 491 ? 143.344 150.943 199.751 1.00 102.13 ? 491 ASP B CA  1 
ATOM   7508  C C   . ASP B 1 491 ? 142.777 151.990 200.700 1.00 102.13 ? 491 ASP B C   1 
ATOM   7509  O O   . ASP B 1 491 ? 142.713 151.744 201.909 1.00 102.13 ? 491 ASP B O   1 
ATOM   7510  C CB  . ASP B 1 491 ? 144.872 150.978 199.793 1.00 102.13 ? 491 ASP B CB  1 
ATOM   7511  C CG  . ASP B 1 491 ? 145.495 149.632 199.482 1.00 102.13 ? 491 ASP B CG  1 
ATOM   7512  O OD1 . ASP B 1 491 ? 144.852 148.599 199.762 1.00 102.13 ? 491 ASP B OD1 1 
ATOM   7513  O OD2 . ASP B 1 491 ? 146.628 149.607 198.957 1.00 102.13 ? 491 ASP B OD2 1 
ATOM   7514  N N   . ILE B 1 492 ? 142.373 153.152 200.183 1.00 102.98 ? 492 ILE B N   1 
ATOM   7515  C CA  . ILE B 1 492 ? 141.807 154.193 201.038 1.00 102.98 ? 492 ILE B CA  1 
ATOM   7516  C C   . ILE B 1 492 ? 140.467 153.742 201.607 1.00 102.98 ? 492 ILE B C   1 
ATOM   7517  O O   . ILE B 1 492 ? 140.196 153.894 202.804 1.00 102.98 ? 492 ILE B O   1 
ATOM   7518  C CB  . ILE B 1 492 ? 141.671 155.512 200.257 1.00 102.98 ? 492 ILE B CB  1 
ATOM   7519  C CG1 . ILE B 1 492 ? 143.043 156.008 199.801 1.00 102.98 ? 492 ILE B CG1 1 
ATOM   7520  C CG2 . ILE B 1 492 ? 140.977 156.565 201.105 1.00 102.98 ? 492 ILE B CG2 1 
ATOM   7521  C CD1 . ILE B 1 492 ? 142.977 157.092 198.749 1.00 102.98 ? 492 ILE B CD1 1 
ATOM   7522  N N   . TYR B 1 493 ? 139.611 153.178 200.757 1.00 102.05 ? 493 TYR B N   1 
ATOM   7523  C CA  . TYR B 1 493 ? 138.257 152.802 201.136 1.00 102.05 ? 493 TYR B CA  1 
ATOM   7524  C C   . TYR B 1 493 ? 138.103 151.307 201.384 1.00 102.05 ? 493 TYR B C   1 
ATOM   7525  O O   . TYR B 1 493 ? 136.972 150.831 201.535 1.00 102.05 ? 493 TYR B O   1 
ATOM   7526  C CB  . TYR B 1 493 ? 137.272 153.244 200.053 1.00 102.05 ? 493 TYR B CB  1 
ATOM   7527  C CG  . TYR B 1 493 ? 137.140 154.741 199.898 1.00 102.05 ? 493 TYR B CG  1 
ATOM   7528  C CD1 . TYR B 1 493 ? 136.341 155.482 200.759 1.00 102.05 ? 493 TYR B CD1 1 
ATOM   7529  C CD2 . TYR B 1 493 ? 137.810 155.414 198.885 1.00 102.05 ? 493 TYR B CD2 1 
ATOM   7530  C CE1 . TYR B 1 493 ? 136.215 156.850 200.617 1.00 102.05 ? 493 TYR B CE1 1 
ATOM   7531  C CE2 . TYR B 1 493 ? 137.691 156.782 198.735 1.00 102.05 ? 493 TYR B CE2 1 
ATOM   7532  C CZ  . TYR B 1 493 ? 136.893 157.495 199.604 1.00 102.05 ? 493 TYR B CZ  1 
ATOM   7533  O OH  . TYR B 1 493 ? 136.772 158.858 199.459 1.00 102.05 ? 493 TYR B OH  1 
ATOM   7534  N N   . ARG B 1 494 ? 139.208 150.555 201.408 1.00 101.97 ? 494 ARG B N   1 
ATOM   7535  C CA  . ARG B 1 494 ? 139.121 149.102 201.527 1.00 101.97 ? 494 ARG B CA  1 
ATOM   7536  C C   . ARG B 1 494 ? 138.454 148.682 202.831 1.00 101.97 ? 494 ARG B C   1 
ATOM   7537  O O   . ARG B 1 494 ? 137.568 147.820 202.836 1.00 101.97 ? 494 ARG B O   1 
ATOM   7538  C CB  . ARG B 1 494 ? 140.516 148.486 201.418 1.00 101.97 ? 494 ARG B CB  1 
ATOM   7539  C CG  . ARG B 1 494 ? 140.521 146.967 201.431 1.00 101.97 ? 494 ARG B CG  1 
ATOM   7540  C CD  . ARG B 1 494 ? 141.782 146.410 200.792 1.00 101.97 ? 494 ARG B CD  1 
ATOM   7541  N NE  . ARG B 1 494 ? 141.968 144.997 201.102 1.00 101.97 ? 494 ARG B NE  1 
ATOM   7542  C CZ  . ARG B 1 494 ? 141.511 144.000 200.357 1.00 101.97 ? 494 ARG B CZ  1 
ATOM   7543  N NH1 . ARG B 1 494 ? 140.835 144.225 199.242 1.00 101.97 ? 494 ARG B NH1 1 
ATOM   7544  N NH2 . ARG B 1 494 ? 141.737 142.747 200.739 1.00 101.97 ? 494 ARG B NH2 1 
ATOM   7545  N N   . ASP B 1 495 ? 138.874 149.274 203.952 1.00 105.75 ? 495 ASP B N   1 
ATOM   7546  C CA  . ASP B 1 495 ? 138.328 148.872 205.244 1.00 105.75 ? 495 ASP B CA  1 
ATOM   7547  C C   . ASP B 1 495 ? 136.842 149.196 205.344 1.00 105.75 ? 495 ASP B C   1 
ATOM   7548  O O   . ASP B 1 495 ? 136.049 148.371 205.814 1.00 105.75 ? 495 ASP B O   1 
ATOM   7549  C CB  . ASP B 1 495 ? 139.102 149.549 206.375 1.00 105.75 ? 495 ASP B CB  1 
ATOM   7550  C CG  . ASP B 1 495 ? 140.600 149.539 206.141 1.00 105.75 ? 495 ASP B CG  1 
ATOM   7551  O OD1 . ASP B 1 495 ? 141.160 148.446 205.913 1.00 105.75 ? 495 ASP B OD1 1 
ATOM   7552  O OD2 . ASP B 1 495 ? 141.217 150.623 206.188 1.00 105.75 ? 495 ASP B OD2 1 
ATOM   7553  N N   . GLU B 1 496 ? 136.447 150.391 204.899 1.00 104.06 ? 496 GLU B N   1 
ATOM   7554  C CA  . GLU B 1 496 ? 135.038 150.768 204.937 1.00 104.06 ? 496 GLU B CA  1 
ATOM   7555  C C   . GLU B 1 496 ? 134.200 149.863 204.042 1.00 104.06 ? 496 GLU B C   1 
ATOM   7556  O O   . GLU B 1 496 ? 133.101 149.443 204.427 1.00 104.06 ? 496 GLU B O   1 
ATOM   7557  C CB  . GLU B 1 496 ? 134.877 152.232 204.530 1.00 104.06 ? 496 GLU B CB  1 
ATOM   7558  C CG  . GLU B 1 496 ? 133.452 152.749 204.613 1.00 104.06 ? 496 GLU B CG  1 
ATOM   7559  C CD  . GLU B 1 496 ? 133.344 154.217 204.250 1.00 104.06 ? 496 GLU B CD  1 
ATOM   7560  O OE1 . GLU B 1 496 ? 134.381 154.826 203.913 1.00 104.06 ? 496 GLU B OE1 1 
ATOM   7561  O OE2 . GLU B 1 496 ? 132.222 154.764 204.301 1.00 104.06 ? 496 GLU B OE2 1 
ATOM   7562  N N   . ALA B 1 497 ? 134.702 149.549 202.845 1.00 104.29 ? 497 ALA B N   1 
ATOM   7563  C CA  . ALA B 1 497 ? 133.961 148.675 201.943 1.00 104.29 ? 497 ALA B CA  1 
ATOM   7564  C C   . ALA B 1 497 ? 133.816 147.272 202.521 1.00 104.29 ? 497 ALA B C   1 
ATOM   7565  O O   . ALA B 1 497 ? 132.742 146.667 202.428 1.00 104.29 ? 497 ALA B O   1 
ATOM   7566  C CB  . ALA B 1 497 ? 134.645 148.628 200.579 1.00 104.29 ? 497 ALA B CB  1 
ATOM   7567  N N   . LEU B 1 498 ? 134.885 146.737 203.118 1.00 103.46 ? 498 LEU B N   1 
ATOM   7568  C CA  . LEU B 1 498 ? 134.800 145.413 203.725 1.00 103.46 ? 498 LEU B CA  1 
ATOM   7569  C C   . LEU B 1 498 ? 133.834 145.408 204.902 1.00 103.46 ? 498 LEU B C   1 
ATOM   7570  O O   . LEU B 1 498 ? 133.090 144.439 205.100 1.00 103.46 ? 498 LEU B O   1 
ATOM   7571  C CB  . LEU B 1 498 ? 136.186 144.942 204.164 1.00 103.46 ? 498 LEU B CB  1 
ATOM   7572  C CG  . LEU B 1 498 ? 137.185 144.627 203.049 1.00 103.46 ? 498 LEU B CG  1 
ATOM   7573  C CD1 . LEU B 1 498 ? 138.536 144.245 203.633 1.00 103.46 ? 498 LEU B CD1 1 
ATOM   7574  C CD2 . LEU B 1 498 ? 136.655 143.526 202.146 1.00 103.46 ? 498 LEU B CD2 1 
ATOM   7575  N N   . ASN B 1 499 ? 133.834 146.478 205.701 1.00 104.18 ? 499 ASN B N   1 
ATOM   7576  C CA  . ASN B 1 499 ? 132.896 146.562 206.816 1.00 104.18 ? 499 ASN B CA  1 
ATOM   7577  C C   . ASN B 1 499 ? 131.455 146.629 206.325 1.00 104.18 ? 499 ASN B C   1 
ATOM   7578  O O   . ASN B 1 499 ? 130.563 146.013 206.919 1.00 104.18 ? 499 ASN B O   1 
ATOM   7579  C CB  . ASN B 1 499 ? 133.223 147.774 207.687 1.00 104.18 ? 499 ASN B CB  1 
ATOM   7580  C CG  . ASN B 1 499 ? 134.448 147.556 208.553 1.00 104.18 ? 499 ASN B CG  1 
ATOM   7581  O OD1 . ASN B 1 499 ? 134.757 146.428 208.937 1.00 104.18 ? 499 ASN B OD1 1 
ATOM   7582  N ND2 . ASN B 1 499 ? 135.152 148.637 208.866 1.00 104.18 ? 499 ASN B ND2 1 
ATOM   7583  N N   . ASN B 1 500 ? 131.206 147.374 205.245 1.00 103.02 ? 500 ASN B N   1 
ATOM   7584  C CA  . ASN B 1 500 ? 129.840 147.506 204.745 1.00 103.02 ? 500 ASN B CA  1 
ATOM   7585  C C   . ASN B 1 500 ? 129.356 146.221 204.083 1.00 103.02 ? 500 ASN B C   1 
ATOM   7586  O O   . ASN B 1 500 ? 128.190 145.839 204.240 1.00 103.02 ? 500 ASN B O   1 
ATOM   7587  C CB  . ASN B 1 500 ? 129.749 148.679 203.770 1.00 103.02 ? 500 ASN B CB  1 
ATOM   7588  C CG  . ASN B 1 500 ? 129.624 150.013 204.476 1.00 103.02 ? 500 ASN B CG  1 
ATOM   7589  O OD1 . ASN B 1 500 ? 128.865 150.153 205.434 1.00 103.02 ? 500 ASN B OD1 1 
ATOM   7590  N ND2 . ASN B 1 500 ? 130.373 151.004 204.006 1.00 103.02 ? 500 ASN B ND2 1 
ATOM   7591  N N   . ARG B 1 501 ? 130.230 145.542 203.335 1.00 100.08 ? 501 ARG B N   1 
ATOM   7592  C CA  . ARG B 1 501 ? 129.817 144.328 202.637 1.00 100.08 ? 501 ARG B CA  1 
ATOM   7593  C C   . ARG B 1 501 ? 129.514 143.198 203.612 1.00 100.08 ? 501 ARG B C   1 
ATOM   7594  O O   . ARG B 1 501 ? 128.502 142.502 203.470 1.00 100.08 ? 501 ARG B O   1 
ATOM   7595  C CB  . ARG B 1 501 ? 130.896 143.897 201.643 1.00 100.08 ? 501 ARG B CB  1 
ATOM   7596  C CG  . ARG B 1 501 ? 131.049 144.825 200.454 1.00 100.08 ? 501 ARG B CG  1 
ATOM   7597  C CD  . ARG B 1 501 ? 132.137 144.351 199.504 1.00 100.08 ? 501 ARG B CD  1 
ATOM   7598  N NE  . ARG B 1 501 ? 131.700 143.221 198.693 1.00 100.08 ? 501 ARG B NE  1 
ATOM   7599  C CZ  . ARG B 1 501 ? 132.501 142.503 197.919 1.00 100.08 ? 501 ARG B CZ  1 
ATOM   7600  N NH1 . ARG B 1 501 ? 133.794 142.767 197.828 1.00 100.08 ? 501 ARG B NH1 1 
ATOM   7601  N NH2 . ARG B 1 501 ? 131.992 141.493 197.218 1.00 100.08 ? 501 ARG B NH2 1 
ATOM   7602  N N   . PHE B 1 502 ? 130.374 143.001 204.606 1.00 101.85 ? 502 PHE B N   1 
ATOM   7603  C CA  . PHE B 1 502 ? 130.229 141.884 205.531 1.00 101.85 ? 502 PHE B CA  1 
ATOM   7604  C C   . PHE B 1 502 ? 129.760 142.359 206.902 1.00 101.85 ? 502 PHE B C   1 
ATOM   7605  O O   . PHE B 1 502 ? 128.634 142.832 207.053 1.00 101.85 ? 502 PHE B O   1 
ATOM   7606  C CB  . PHE B 1 502 ? 131.552 141.126 205.657 1.00 101.85 ? 502 PHE B CB  1 
ATOM   7607  C CG  . PHE B 1 502 ? 132.114 140.665 204.341 1.00 101.85 ? 502 PHE B CG  1 
ATOM   7608  C CD1 . PHE B 1 502 ? 131.275 140.245 203.322 1.00 101.85 ? 502 PHE B CD1 1 
ATOM   7609  C CD2 . PHE B 1 502 ? 133.481 140.655 204.122 1.00 101.85 ? 502 PHE B CD2 1 
ATOM   7610  C CE1 . PHE B 1 502 ? 131.788 139.822 202.111 1.00 101.85 ? 502 PHE B CE1 1 
ATOM   7611  C CE2 . PHE B 1 502 ? 134.000 140.234 202.913 1.00 101.85 ? 502 PHE B CE2 1 
ATOM   7612  C CZ  . PHE B 1 502 ? 133.153 139.817 201.906 1.00 101.85 ? 502 PHE B CZ  1 
ATOM   7613  N N   . THR C 1 12  ? 124.369 122.760 201.173 1.00 89.15  ? 12  THR C N   1 
ATOM   7614  C CA  . THR C 1 12  ? 125.089 123.121 199.959 1.00 89.15  ? 12  THR C CA  1 
ATOM   7615  C C   . THR C 1 12  ? 124.475 122.441 198.739 1.00 89.15  ? 12  THR C C   1 
ATOM   7616  O O   . THR C 1 12  ? 123.684 121.505 198.871 1.00 89.15  ? 12  THR C O   1 
ATOM   7617  C CB  . THR C 1 12  ? 126.577 122.748 200.053 1.00 89.15  ? 12  THR C CB  1 
ATOM   7618  O OG1 . THR C 1 12  ? 126.704 121.336 200.261 1.00 89.15  ? 12  THR C OG1 1 
ATOM   7619  C CG2 . THR C 1 12  ? 127.234 123.486 201.210 1.00 89.15  ? 12  THR C CG2 1 
ATOM   7620  N N   . ALA C 1 13  ? 124.843 122.918 197.554 1.00 85.71  ? 13  ALA C N   1 
ATOM   7621  C CA  . ALA C 1 13  ? 124.286 122.400 196.312 1.00 85.71  ? 13  ALA C CA  1 
ATOM   7622  C C   . ALA C 1 13  ? 125.279 122.649 195.185 1.00 85.71  ? 13  ALA C C   1 
ATOM   7623  O O   . ALA C 1 13  ? 126.265 123.371 195.344 1.00 85.71  ? 13  ALA C O   1 
ATOM   7624  C CB  . ALA C 1 13  ? 122.929 123.037 196.000 1.00 85.71  ? 13  ALA C CB  1 
ATOM   7625  N N   . THR C 1 14  ? 124.998 122.038 194.036 1.00 81.04  ? 14  THR C N   1 
ATOM   7626  C CA  . THR C 1 14  ? 125.855 122.115 192.862 1.00 81.04  ? 14  THR C CA  1 
ATOM   7627  C C   . THR C 1 14  ? 124.995 122.358 191.630 1.00 81.04  ? 14  THR C C   1 
ATOM   7628  O O   . THR C 1 14  ? 123.952 121.723 191.458 1.00 81.04  ? 14  THR C O   1 
ATOM   7629  C CB  . THR C 1 14  ? 126.677 120.826 192.699 1.00 81.04  ? 14  THR C CB  1 
ATOM   7630  O OG1 . THR C 1 14  ? 127.738 120.806 193.661 1.00 81.04  ? 14  THR C OG1 1 
ATOM   7631  C CG2 . THR C 1 14  ? 127.272 120.729 191.310 1.00 81.04  ? 14  THR C CG2 1 
ATOM   7632  N N   . LEU C 1 15  ? 125.431 123.284 190.776 1.00 75.94  ? 15  LEU C N   1 
ATOM   7633  C CA  . LEU C 1 15  ? 124.717 123.627 189.549 1.00 75.94  ? 15  LEU C CA  1 
ATOM   7634  C C   . LEU C 1 15  ? 125.721 123.720 188.410 1.00 75.94  ? 15  LEU C C   1 
ATOM   7635  O O   . LEU C 1 15  ? 126.539 124.645 188.374 1.00 75.94  ? 15  LEU C O   1 
ATOM   7636  C CB  . LEU C 1 15  ? 123.957 124.942 189.703 1.00 75.94  ? 15  LEU C CB  1 
ATOM   7637  C CG  . LEU C 1 15  ? 123.049 125.324 188.534 1.00 75.94  ? 15  LEU C CG  1 
ATOM   7638  C CD1 . LEU C 1 15  ? 121.892 124.346 188.408 1.00 75.94  ? 15  LEU C CD1 1 
ATOM   7639  C CD2 . LEU C 1 15  ? 122.541 126.746 188.692 1.00 75.94  ? 15  LEU C CD2 1 
ATOM   7640  N N   . CYS C 1 16  ? 125.653 122.774 187.478 1.00 71.93  ? 16  CYS C N   1 
ATOM   7641  C CA  . CYS C 1 16  ? 126.576 122.706 186.355 1.00 71.93  ? 16  CYS C CA  1 
ATOM   7642  C C   . CYS C 1 16  ? 125.882 123.128 185.065 1.00 71.93  ? 16  CYS C C   1 
ATOM   7643  O O   . CYS C 1 16  ? 124.653 123.103 184.965 1.00 71.93  ? 16  CYS C O   1 
ATOM   7644  C CB  . CYS C 1 16  ? 127.144 121.292 186.199 1.00 71.93  ? 16  CYS C CB  1 
ATOM   7645  S SG  . CYS C 1 16  ? 128.118 120.684 187.603 1.00 71.93  ? 16  CYS C SG  1 
ATOM   7646  N N   . LEU C 1 17  ? 126.684 123.525 184.079 1.00 66.46  ? 17  LEU C N   1 
ATOM   7647  C CA  . LEU C 1 17  ? 126.198 123.902 182.759 1.00 66.46  ? 17  LEU C CA  1 
ATOM   7648  C C   . LEU C 1 17  ? 126.943 123.104 181.698 1.00 66.46  ? 17  LEU C C   1 
ATOM   7649  O O   . LEU C 1 17  ? 128.145 122.859 181.828 1.00 66.46  ? 17  LEU C O   1 
ATOM   7650  C CB  . LEU C 1 17  ? 126.379 125.402 182.501 1.00 66.46  ? 17  LEU C CB  1 
ATOM   7651  C CG  . LEU C 1 17  ? 125.369 126.357 183.137 1.00 66.46  ? 17  LEU C CG  1 
ATOM   7652  C CD1 . LEU C 1 17  ? 125.713 126.631 184.594 1.00 66.46  ? 17  LEU C CD1 1 
ATOM   7653  C CD2 . LEU C 1 17  ? 125.299 127.654 182.353 1.00 66.46  ? 17  LEU C CD2 1 
ATOM   7654  N N   . GLY C 1 18  ? 126.231 122.701 180.649 1.00 63.04  ? 18  GLY C N   1 
ATOM   7655  C CA  . GLY C 1 18  ? 126.843 121.873 179.628 1.00 63.04  ? 18  GLY C CA  1 
ATOM   7656  C C   . GLY C 1 18  ? 126.067 121.917 178.330 1.00 63.04  ? 18  GLY C C   1 
ATOM   7657  O O   . GLY C 1 18  ? 125.026 122.568 178.221 1.00 63.04  ? 18  GLY C O   1 
ATOM   7658  N N   . HIS C 1 19  ? 126.598 121.206 177.337 1.00 59.42  ? 19  HIS C N   1 
ATOM   7659  C CA  . HIS C 1 19  ? 126.007 121.150 176.008 1.00 59.42  ? 19  HIS C CA  1 
ATOM   7660  C C   . HIS C 1 19  ? 125.959 119.705 175.534 1.00 59.42  ? 19  HIS C C   1 
ATOM   7661  O O   . HIS C 1 19  ? 126.625 118.825 176.085 1.00 59.42  ? 19  HIS C O   1 
ATOM   7662  C CB  . HIS C 1 19  ? 126.780 122.018 175.003 1.00 59.42  ? 19  HIS C CB  1 
ATOM   7663  C CG  . HIS C 1 19  ? 128.242 121.707 174.930 1.00 59.42  ? 19  HIS C CG  1 
ATOM   7664  N ND1 . HIS C 1 19  ? 128.736 120.587 174.296 1.00 59.42  ? 19  HIS C ND1 1 
ATOM   7665  C CD2 . HIS C 1 19  ? 129.319 122.376 175.404 1.00 59.42  ? 19  HIS C CD2 1 
ATOM   7666  C CE1 . HIS C 1 19  ? 130.054 120.577 174.388 1.00 59.42  ? 19  HIS C CE1 1 
ATOM   7667  N NE2 . HIS C 1 19  ? 130.433 121.651 175.056 1.00 59.42  ? 19  HIS C NE2 1 
ATOM   7668  N N   . HIS C 1 20  ? 125.160 119.470 174.496 1.00 60.38  ? 20  HIS C N   1 
ATOM   7669  C CA  . HIS C 1 20  ? 124.897 118.123 174.015 1.00 60.38  ? 20  HIS C CA  1 
ATOM   7670  C C   . HIS C 1 20  ? 126.013 117.639 173.090 1.00 60.38  ? 20  HIS C C   1 
ATOM   7671  O O   . HIS C 1 20  ? 126.831 118.413 172.589 1.00 60.38  ? 20  HIS C O   1 
ATOM   7672  C CB  . HIS C 1 20  ? 123.552 118.068 173.292 1.00 60.38  ? 20  HIS C CB  1 
ATOM   7673  C CG  . HIS C 1 20  ? 123.607 118.543 171.873 1.00 60.38  ? 20  HIS C CG  1 
ATOM   7674  N ND1 . HIS C 1 20  ? 123.647 119.879 171.535 1.00 60.38  ? 20  HIS C ND1 1 
ATOM   7675  C CD2 . HIS C 1 20  ? 123.622 117.860 170.704 1.00 60.38  ? 20  HIS C CD2 1 
ATOM   7676  C CE1 . HIS C 1 20  ? 123.688 119.998 170.221 1.00 60.38  ? 20  HIS C CE1 1 
ATOM   7677  N NE2 . HIS C 1 20  ? 123.674 118.788 169.692 1.00 60.38  ? 20  HIS C NE2 1 
ATOM   7678  N N   . SER C 1 21  ? 126.036 116.326 172.872 1.00 61.01  ? 21  SER C N   1 
ATOM   7679  C CA  . SER C 1 21  ? 126.971 115.701 171.948 1.00 61.01  ? 21  SER C CA  1 
ATOM   7680  C C   . SER C 1 21  ? 126.293 114.493 171.322 1.00 61.01  ? 21  SER C C   1 
ATOM   7681  O O   . SER C 1 21  ? 125.295 113.983 171.836 1.00 61.01  ? 21  SER C O   1 
ATOM   7682  C CB  . SER C 1 21  ? 128.274 115.292 172.645 1.00 61.01  ? 21  SER C CB  1 
ATOM   7683  O OG  . SER C 1 21  ? 128.056 114.216 173.540 1.00 61.01  ? 21  SER C OG  1 
ATOM   7684  N N   . VAL C 1 22  ? 126.845 114.037 170.202 1.00 58.41  ? 22  VAL C N   1 
ATOM   7685  C CA  . VAL C 1 22  ? 126.253 112.931 169.451 1.00 58.41  ? 22  VAL C CA  1 
ATOM   7686  C C   . VAL C 1 22  ? 127.270 111.802 169.324 1.00 58.41  ? 22  VAL C C   1 
ATOM   7687  O O   . VAL C 1 22  ? 128.483 112.059 169.320 1.00 58.41  ? 22  VAL C O   1 
ATOM   7688  C CB  . VAL C 1 22  ? 125.759 113.399 168.072 1.00 58.41  ? 22  VAL C CB  1 
ATOM   7689  C CG1 . VAL C 1 22  ? 124.684 114.463 168.229 1.00 58.41  ? 22  VAL C CG1 1 
ATOM   7690  C CG2 . VAL C 1 22  ? 126.915 113.928 167.242 1.00 58.41  ? 22  VAL C CG2 1 
ATOM   7691  N N   . PRO C 1 23  ? 126.828 110.544 169.240 1.00 60.39  ? 23  PRO C N   1 
ATOM   7692  C CA  . PRO C 1 23  ? 127.794 109.435 169.138 1.00 60.39  ? 23  PRO C CA  1 
ATOM   7693  C C   . PRO C 1 23  ? 128.657 109.484 167.890 1.00 60.39  ? 23  PRO C C   1 
ATOM   7694  O O   . PRO C 1 23  ? 129.825 109.078 167.944 1.00 60.39  ? 23  PRO C O   1 
ATOM   7695  C CB  . PRO C 1 23  ? 126.899 108.188 169.158 1.00 60.39  ? 23  PRO C CB  1 
ATOM   7696  C CG  . PRO C 1 23  ? 125.544 108.670 168.764 1.00 60.39  ? 23  PRO C CG  1 
ATOM   7697  C CD  . PRO C 1 23  ? 125.437 110.066 169.286 1.00 60.39  ? 23  PRO C CD  1 
ATOM   7698  N N   . ASN C 1 24  ? 128.126 109.962 166.767 1.00 58.20  ? 24  ASN C N   1 
ATOM   7699  C CA  . ASN C 1 24  ? 128.872 110.031 165.516 1.00 58.20  ? 24  ASN C CA  1 
ATOM   7700  C C   . ASN C 1 24  ? 128.780 111.437 164.940 1.00 58.20  ? 24  ASN C C   1 
ATOM   7701  O O   . ASN C 1 24  ? 127.681 111.973 164.768 1.00 58.20  ? 24  ASN C O   1 
ATOM   7702  C CB  . ASN C 1 24  ? 128.370 108.984 164.514 1.00 58.20  ? 24  ASN C CB  1 
ATOM   7703  C CG  . ASN C 1 24  ? 126.879 109.086 164.243 1.00 58.20  ? 24  ASN C CG  1 
ATOM   7704  O OD1 . ASN C 1 24  ? 126.156 109.819 164.918 1.00 58.20  ? 24  ASN C OD1 1 
ATOM   7705  N ND2 . ASN C 1 24  ? 126.411 108.345 163.246 1.00 58.20  ? 24  ASN C ND2 1 
ATOM   7706  N N   . GLY C 1 25  ? 129.935 112.033 164.648 1.00 51.04  ? 25  GLY C N   1 
ATOM   7707  C CA  . GLY C 1 25  ? 130.010 113.367 164.103 1.00 51.04  ? 25  GLY C CA  1 
ATOM   7708  C C   . GLY C 1 25  ? 130.650 113.403 162.724 1.00 51.04  ? 25  GLY C C   1 
ATOM   7709  O O   . GLY C 1 25  ? 131.071 112.395 162.163 1.00 51.04  ? 25  GLY C O   1 
ATOM   7710  N N   . THR C 1 26  ? 130.715 114.616 162.184 1.00 44.54  ? 26  THR C N   1 
ATOM   7711  C CA  . THR C 1 26  ? 131.286 114.870 160.871 1.00 44.54  ? 26  THR C CA  1 
ATOM   7712  C C   . THR C 1 26  ? 132.441 115.854 160.994 1.00 44.54  ? 26  THR C C   1 
ATOM   7713  O O   . THR C 1 26  ? 132.441 116.730 161.862 1.00 44.54  ? 26  THR C O   1 
ATOM   7714  C CB  . THR C 1 26  ? 130.234 115.424 159.904 1.00 44.54  ? 26  THR C CB  1 
ATOM   7715  O OG1 . THR C 1 26  ? 129.709 116.650 160.423 1.00 44.54  ? 26  THR C OG1 1 
ATOM   7716  C CG2 . THR C 1 26  ? 129.099 114.431 159.728 1.00 44.54  ? 26  THR C CG2 1 
ATOM   7717  N N   . ILE C 1 27  ? 133.426 115.704 160.114 1.00 41.64  ? 27  ILE C N   1 
ATOM   7718  C CA  . ILE C 1 27  ? 134.626 116.533 160.122 1.00 41.64  ? 27  ILE C CA  1 
ATOM   7719  C C   . ILE C 1 27  ? 134.504 117.590 159.034 1.00 41.64  ? 27  ILE C C   1 
ATOM   7720  O O   . ILE C 1 27  ? 134.290 117.264 157.860 1.00 41.64  ? 27  ILE C O   1 
ATOM   7721  C CB  . ILE C 1 27  ? 135.891 115.680 159.927 1.00 41.64  ? 27  ILE C CB  1 
ATOM   7722  C CG1 . ILE C 1 27  ? 136.204 114.896 161.202 1.00 41.64  ? 27  ILE C CG1 1 
ATOM   7723  C CG2 . ILE C 1 27  ? 137.070 116.552 159.536 1.00 41.64  ? 27  ILE C CG2 1 
ATOM   7724  C CD1 . ILE C 1 27  ? 137.342 113.919 161.052 1.00 41.64  ? 27  ILE C CD1 1 
ATOM   7725  N N   . VAL C 1 28  ? 134.639 118.857 159.424 1.00 39.93  ? 28  VAL C N   1 
ATOM   7726  C CA  . VAL C 1 28  ? 134.595 119.974 158.487 1.00 39.93  ? 28  VAL C CA  1 
ATOM   7727  C C   . VAL C 1 28  ? 135.905 120.745 158.576 1.00 39.93  ? 28  VAL C C   1 
ATOM   7728  O O   . VAL C 1 28  ? 136.778 120.414 159.385 1.00 39.93  ? 28  VAL C O   1 
ATOM   7729  C CB  . VAL C 1 28  ? 133.390 120.893 158.761 1.00 39.93  ? 28  VAL C CB  1 
ATOM   7730  C CG1 . VAL C 1 28  ? 132.093 120.101 158.716 1.00 39.93  ? 28  VAL C CG1 1 
ATOM   7731  C CG2 . VAL C 1 28  ? 133.545 121.591 160.100 1.00 39.93  ? 28  VAL C CG2 1 
ATOM   7732  N N   . LYS C 1 29  ? 136.052 121.775 157.746 1.00 39.46  ? 29  LYS C N   1 
ATOM   7733  C CA  . LYS C 1 29  ? 137.264 122.582 157.700 1.00 39.46  ? 29  LYS C CA  1 
ATOM   7734  C C   . LYS C 1 29  ? 136.914 124.050 157.891 1.00 39.46  ? 29  LYS C C   1 
ATOM   7735  O O   . LYS C 1 29  ? 135.987 124.563 157.258 1.00 39.46  ? 29  LYS C O   1 
ATOM   7736  C CB  . LYS C 1 29  ? 138.010 122.389 156.375 1.00 39.46  ? 29  LYS C CB  1 
ATOM   7737  C CG  . LYS C 1 29  ? 139.266 123.231 156.244 1.00 39.46  ? 29  LYS C CG  1 
ATOM   7738  C CD  . LYS C 1 29  ? 140.091 122.811 155.043 1.00 39.46  ? 29  LYS C CD  1 
ATOM   7739  C CE  . LYS C 1 29  ? 139.439 123.250 153.745 1.00 39.46  ? 29  LYS C CE  1 
ATOM   7740  N NZ  . LYS C 1 29  ? 140.310 122.972 152.570 1.00 39.46  ? 29  LYS C NZ  1 
ATOM   7741  N N   . THR C 1 30  ? 137.662 124.720 158.760 1.00 39.76  ? 30  THR C N   1 
ATOM   7742  C CA  . THR C 1 30  ? 137.464 126.129 159.072 1.00 39.76  ? 30  THR C CA  1 
ATOM   7743  C C   . THR C 1 30  ? 138.710 126.920 158.669 1.00 39.76  ? 30  THR C C   1 
ATOM   7744  O O   . THR C 1 30  ? 139.630 126.393 158.038 1.00 39.76  ? 30  THR C O   1 
ATOM   7745  C CB  . THR C 1 30  ? 137.138 126.313 160.557 1.00 39.76  ? 30  THR C CB  1 
ATOM   7746  O OG1 . THR C 1 30  ? 138.294 126.009 161.345 1.00 39.76  ? 30  THR C OG1 1 
ATOM   7747  C CG2 . THR C 1 30  ? 135.999 125.397 160.972 1.00 39.76  ? 30  THR C CG2 1 
ATOM   7748  N N   . ILE C 1 31  ? 138.726 128.204 159.031 1.00 39.88  ? 31  ILE C N   1 
ATOM   7749  C CA  . ILE C 1 31  ? 139.859 129.061 158.693 1.00 39.88  ? 31  ILE C CA  1 
ATOM   7750  C C   . ILE C 1 31  ? 141.101 128.647 159.474 1.00 39.88  ? 31  ILE C C   1 
ATOM   7751  O O   . ILE C 1 31  ? 142.198 128.537 158.915 1.00 39.88  ? 31  ILE C O   1 
ATOM   7752  C CB  . ILE C 1 31  ? 139.505 130.539 158.939 1.00 39.88  ? 31  ILE C CB  1 
ATOM   7753  C CG1 . ILE C 1 31  ? 138.526 131.039 157.877 1.00 39.88  ? 31  ILE C CG1 1 
ATOM   7754  C CG2 . ILE C 1 31  ? 140.758 131.398 158.950 1.00 39.88  ? 31  ILE C CG2 1 
ATOM   7755  C CD1 . ILE C 1 31  ? 139.096 131.047 156.481 1.00 39.88  ? 31  ILE C CD1 1 
ATOM   7756  N N   . THR C 1 32  ? 140.950 128.408 160.777 1.00 43.89  ? 32  THR C N   1 
ATOM   7757  C CA  . THR C 1 32  ? 142.088 128.092 161.631 1.00 43.89  ? 32  THR C CA  1 
ATOM   7758  C C   . THR C 1 32  ? 142.282 126.601 161.867 1.00 43.89  ? 32  THR C C   1 
ATOM   7759  O O   . THR C 1 32  ? 143.319 126.209 162.413 1.00 43.89  ? 32  THR C O   1 
ATOM   7760  C CB  . THR C 1 32  ? 141.949 128.793 162.989 1.00 43.89  ? 32  THR C CB  1 
ATOM   7761  O OG1 . THR C 1 32  ? 140.734 128.377 163.623 1.00 43.89  ? 32  THR C OG1 1 
ATOM   7762  C CG2 . THR C 1 32  ? 141.936 130.304 162.811 1.00 43.89  ? 32  THR C CG2 1 
ATOM   7763  N N   . ASP C 1 33  ? 141.325 125.765 161.476 1.00 46.49  ? 33  ASP C N   1 
ATOM   7764  C CA  . ASP C 1 33  ? 141.425 124.323 161.644 1.00 46.49  ? 33  ASP C CA  1 
ATOM   7765  C C   . ASP C 1 33  ? 141.247 123.635 160.300 1.00 46.49  ? 33  ASP C C   1 
ATOM   7766  O O   . ASP C 1 33  ? 140.382 124.018 159.506 1.00 46.49  ? 33  ASP C O   1 
ATOM   7767  C CB  . ASP C 1 33  ? 140.377 123.803 162.634 1.00 46.49  ? 33  ASP C CB  1 
ATOM   7768  C CG  . ASP C 1 33  ? 140.646 124.248 164.056 1.00 46.49  ? 33  ASP C CG  1 
ATOM   7769  O OD1 . ASP C 1 33  ? 141.828 124.453 164.404 1.00 46.49  ? 33  ASP C OD1 1 
ATOM   7770  O OD2 . ASP C 1 33  ? 139.675 124.395 164.827 1.00 46.49  ? 33  ASP C OD2 1 
ATOM   7771  N N   . ASP C 1 34  ? 142.068 122.617 160.048 1.00 49.72  ? 34  ASP C N   1 
ATOM   7772  C CA  . ASP C 1 34  ? 141.930 121.816 158.840 1.00 49.72  ? 34  ASP C CA  1 
ATOM   7773  C C   . ASP C 1 34  ? 140.997 120.627 159.017 1.00 49.72  ? 34  ASP C C   1 
ATOM   7774  O O   . ASP C 1 34  ? 140.404 120.172 158.033 1.00 49.72  ? 34  ASP C O   1 
ATOM   7775  C CB  . ASP C 1 34  ? 143.307 121.337 158.362 1.00 49.72  ? 34  ASP C CB  1 
ATOM   7776  C CG  . ASP C 1 34  ? 144.001 120.431 159.364 1.00 49.72  ? 34  ASP C CG  1 
ATOM   7777  O OD1 . ASP C 1 34  ? 143.449 120.193 160.459 1.00 49.72  ? 34  ASP C OD1 1 
ATOM   7778  O OD2 . ASP C 1 34  ? 145.112 119.952 159.052 1.00 49.72  ? 34  ASP C OD2 1 
ATOM   7779  N N   . GLN C 1 35  ? 140.853 120.118 160.240 1.00 48.98  ? 35  GLN C N   1 
ATOM   7780  C CA  . GLN C 1 35  ? 139.891 119.065 160.550 1.00 48.98  ? 35  GLN C CA  1 
ATOM   7781  C C   . GLN C 1 35  ? 139.329 119.320 161.938 1.00 48.98  ? 35  GLN C C   1 
ATOM   7782  O O   . GLN C 1 35  ? 140.074 119.305 162.923 1.00 48.98  ? 35  GLN C O   1 
ATOM   7783  C CB  . GLN C 1 35  ? 140.527 117.672 160.485 1.00 48.98  ? 35  GLN C CB  1 
ATOM   7784  C CG  . GLN C 1 35  ? 140.964 117.234 159.100 1.00 48.98  ? 35  GLN C CG  1 
ATOM   7785  C CD  . GLN C 1 35  ? 141.599 115.860 159.101 1.00 48.98  ? 35  GLN C CD  1 
ATOM   7786  O OE1 . GLN C 1 35  ? 141.780 115.248 160.153 1.00 48.98  ? 35  GLN C OE1 1 
ATOM   7787  N NE2 . GLN C 1 35  ? 141.939 115.365 157.917 1.00 48.98  ? 35  GLN C NE2 1 
ATOM   7788  N N   . ILE C 1 36  ? 138.023 119.557 162.014 1.00 44.22  ? 36  ILE C N   1 
ATOM   7789  C CA  . ILE C 1 36  ? 137.324 119.724 163.282 1.00 44.22  ? 36  ILE C CA  1 
ATOM   7790  C C   . ILE C 1 36  ? 136.001 118.975 163.196 1.00 44.22  ? 36  ILE C C   1 
ATOM   7791  O O   . ILE C 1 36  ? 135.332 118.987 162.157 1.00 44.22  ? 36  ILE C O   1 
ATOM   7792  C CB  . ILE C 1 36  ? 137.123 121.216 163.634 1.00 44.22  ? 36  ILE C CB  1 
ATOM   7793  C CG1 . ILE C 1 36  ? 136.713 121.375 165.099 1.00 44.22  ? 36  ILE C CG1 1 
ATOM   7794  C CG2 . ILE C 1 36  ? 136.124 121.884 162.702 1.00 44.22  ? 36  ILE C CG2 1 
ATOM   7795  C CD1 . ILE C 1 36  ? 136.726 122.807 165.581 1.00 44.22  ? 36  ILE C CD1 1 
ATOM   7796  N N   . GLU C 1 37  ? 135.637 118.297 164.280 1.00 47.51  ? 37  GLU C N   1 
ATOM   7797  C CA  . GLU C 1 37  ? 134.456 117.446 164.310 1.00 47.51  ? 37  GLU C CA  1 
ATOM   7798  C C   . GLU C 1 37  ? 133.270 118.224 164.862 1.00 47.51  ? 37  GLU C C   1 
ATOM   7799  O O   . GLU C 1 37  ? 133.383 118.887 165.898 1.00 47.51  ? 37  GLU C O   1 
ATOM   7800  C CB  . GLU C 1 37  ? 134.708 116.196 165.153 1.00 47.51  ? 37  GLU C CB  1 
ATOM   7801  C CG  . GLU C 1 37  ? 133.710 115.078 164.912 1.00 47.51  ? 37  GLU C CG  1 
ATOM   7802  C CD  . GLU C 1 37  ? 133.886 113.921 165.873 1.00 47.51  ? 37  GLU C CD  1 
ATOM   7803  O OE1 . GLU C 1 37  ? 135.032 113.453 166.037 1.00 47.51  ? 37  GLU C OE1 1 
ATOM   7804  O OE2 . GLU C 1 37  ? 132.880 113.479 166.465 1.00 47.51  ? 37  GLU C OE2 1 
ATOM   7805  N N   . VAL C 1 38  ? 132.136 118.139 164.167 1.00 44.66  ? 38  VAL C N   1 
ATOM   7806  C CA  . VAL C 1 38  ? 130.912 118.820 164.560 1.00 44.66  ? 38  VAL C CA  1 
ATOM   7807  C C   . VAL C 1 38  ? 129.794 117.791 164.669 1.00 44.66  ? 38  VAL C C   1 
ATOM   7808  O O   . VAL C 1 38  ? 129.920 116.651 164.222 1.00 44.66  ? 38  VAL C O   1 
ATOM   7809  C CB  . VAL C 1 38  ? 130.523 119.946 163.579 1.00 44.66  ? 38  VAL C CB  1 
ATOM   7810  C CG1 . VAL C 1 38  ? 131.548 121.065 163.624 1.00 44.66  ? 38  VAL C CG1 1 
ATOM   7811  C CG2 . VAL C 1 38  ? 130.389 119.400 162.169 1.00 44.66  ? 38  VAL C CG2 1 
ATOM   7812  N N   . THR C 1 39  ? 128.687 118.211 165.281 1.00 45.28  ? 39  THR C N   1 
ATOM   7813  C CA  . THR C 1 39  ? 127.567 117.308 165.509 1.00 45.28  ? 39  THR C CA  1 
ATOM   7814  C C   . THR C 1 39  ? 126.706 117.095 164.270 1.00 45.28  ? 39  THR C C   1 
ATOM   7815  O O   . THR C 1 39  ? 125.962 116.109 164.216 1.00 45.28  ? 39  THR C O   1 
ATOM   7816  C CB  . THR C 1 39  ? 126.685 117.830 166.647 1.00 45.28  ? 39  THR C CB  1 
ATOM   7817  O OG1 . THR C 1 39  ? 126.071 119.063 166.254 1.00 45.28  ? 39  THR C OG1 1 
ATOM   7818  C CG2 . THR C 1 39  ? 127.509 118.061 167.902 1.00 45.28  ? 39  THR C CG2 1 
ATOM   7819  N N   . ASN C 1 40  ? 126.790 117.979 163.278 1.00 44.26  ? 40  ASN C N   1 
ATOM   7820  C CA  . ASN C 1 40  ? 125.896 117.911 162.131 1.00 44.26  ? 40  ASN C CA  1 
ATOM   7821  C C   . ASN C 1 40  ? 126.464 118.761 161.004 1.00 44.26  ? 40  ASN C C   1 
ATOM   7822  O O   . ASN C 1 40  ? 126.998 119.845 161.248 1.00 44.26  ? 40  ASN C O   1 
ATOM   7823  C CB  . ASN C 1 40  ? 124.491 118.390 162.515 1.00 44.26  ? 40  ASN C CB  1 
ATOM   7824  C CG  . ASN C 1 40  ? 123.441 118.016 161.491 1.00 44.26  ? 40  ASN C CG  1 
ATOM   7825  O OD1 . ASN C 1 40  ? 123.626 117.097 160.694 1.00 44.26  ? 40  ASN C OD1 1 
ATOM   7826  N ND2 . ASN C 1 40  ? 122.324 118.731 161.514 1.00 44.26  ? 40  ASN C ND2 1 
ATOM   7827  N N   . ALA C 1 41  ? 126.342 118.263 159.774 1.00 38.79  ? 41  ALA C N   1 
ATOM   7828  C CA  . ALA C 1 41  ? 126.824 118.980 158.602 1.00 38.79  ? 41  ALA C CA  1 
ATOM   7829  C C   . ALA C 1 41  ? 125.987 118.590 157.393 1.00 38.79  ? 41  ALA C C   1 
ATOM   7830  O O   . ALA C 1 41  ? 125.312 117.558 157.386 1.00 38.79  ? 41  ALA C O   1 
ATOM   7831  C CB  . ALA C 1 41  ? 128.307 118.701 158.336 1.00 38.79  ? 41  ALA C CB  1 
ATOM   7832  N N   . THR C 1 42  ? 126.042 119.433 156.363 1.00 33.63  ? 42  THR C N   1 
ATOM   7833  C CA  . THR C 1 42  ? 125.299 119.219 155.130 1.00 33.63  ? 42  THR C CA  1 
ATOM   7834  C C   . THR C 1 42  ? 126.236 119.316 153.934 1.00 33.63  ? 42  THR C C   1 
ATOM   7835  O O   . THR C 1 42  ? 127.266 119.994 153.983 1.00 33.63  ? 42  THR C O   1 
ATOM   7836  C CB  . THR C 1 42  ? 124.148 120.229 154.978 1.00 33.63  ? 42  THR C CB  1 
ATOM   7837  O OG1 . THR C 1 42  ? 123.341 119.872 153.850 1.00 33.63  ? 42  THR C OG1 1 
ATOM   7838  C CG2 . THR C 1 42  ? 124.684 121.637 154.787 1.00 33.63  ? 42  THR C CG2 1 
ATOM   7839  N N   . GLU C 1 43  ? 125.873 118.619 152.861 1.00 30.15  ? 43  GLU C N   1 
ATOM   7840  C CA  . GLU C 1 43  ? 126.657 118.610 151.633 1.00 30.15  ? 43  GLU C CA  1 
ATOM   7841  C C   . GLU C 1 43  ? 126.174 119.717 150.706 1.00 30.15  ? 43  GLU C C   1 
ATOM   7842  O O   . GLU C 1 43  ? 124.967 119.897 150.519 1.00 30.15  ? 43  GLU C O   1 
ATOM   7843  C CB  . GLU C 1 43  ? 126.556 117.250 150.942 1.00 30.15  ? 43  GLU C CB  1 
ATOM   7844  C CG  . GLU C 1 43  ? 127.244 117.184 149.591 1.00 30.15  ? 43  GLU C CG  1 
ATOM   7845  C CD  . GLU C 1 43  ? 128.752 117.255 149.702 1.00 30.15  ? 43  GLU C CD  1 
ATOM   7846  O OE1 . GLU C 1 43  ? 129.342 116.386 150.377 1.00 30.15  ? 43  GLU C OE1 1 
ATOM   7847  O OE2 . GLU C 1 43  ? 129.350 118.179 149.114 1.00 30.15  ? 43  GLU C OE2 1 
ATOM   7848  N N   . LEU C 1 44  ? 127.120 120.456 150.125 1.00 27.38  ? 44  LEU C N   1 
ATOM   7849  C CA  . LEU C 1 44  ? 126.803 121.614 149.302 1.00 27.38  ? 44  LEU C CA  1 
ATOM   7850  C C   . LEU C 1 44  ? 127.012 121.392 147.811 1.00 27.38  ? 44  LEU C C   1 
ATOM   7851  O O   . LEU C 1 44  ? 126.661 122.275 147.021 1.00 27.38  ? 44  LEU C O   1 
ATOM   7852  C CB  . LEU C 1 44  ? 127.642 122.823 149.744 1.00 27.38  ? 44  LEU C CB  1 
ATOM   7853  C CG  . LEU C 1 44  ? 127.347 123.433 151.115 1.00 27.38  ? 44  LEU C CG  1 
ATOM   7854  C CD1 . LEU C 1 44  ? 128.145 124.710 151.300 1.00 27.38  ? 44  LEU C CD1 1 
ATOM   7855  C CD2 . LEU C 1 44  ? 125.862 123.699 151.289 1.00 27.38  ? 44  LEU C CD2 1 
ATOM   7856  N N   . VAL C 1 45  ? 127.567 120.254 147.401 1.00 25.90  ? 45  VAL C N   1 
ATOM   7857  C CA  . VAL C 1 45  ? 127.896 119.991 146.004 1.00 25.90  ? 45  VAL C CA  1 
ATOM   7858  C C   . VAL C 1 45  ? 127.078 118.803 145.520 1.00 25.90  ? 45  VAL C C   1 
ATOM   7859  O O   . VAL C 1 45  ? 127.085 117.740 146.151 1.00 25.90  ? 45  VAL C O   1 
ATOM   7860  C CB  . VAL C 1 45  ? 129.402 119.730 145.815 1.00 25.90  ? 45  VAL C CB  1 
ATOM   7861  C CG1 . VAL C 1 45  ? 129.700 119.346 144.378 1.00 25.90  ? 45  VAL C CG1 1 
ATOM   7862  C CG2 . VAL C 1 45  ? 130.206 120.952 146.215 1.00 25.90  ? 45  VAL C CG2 1 
ATOM   7863  N N   . GLN C 1 46  ? 126.376 118.986 144.404 1.00 26.57  ? 46  GLN C N   1 
ATOM   7864  C CA  . GLN C 1 46  ? 125.640 117.911 143.753 1.00 26.57  ? 46  GLN C CA  1 
ATOM   7865  C C   . GLN C 1 46  ? 126.552 117.219 142.748 1.00 26.57  ? 46  GLN C C   1 
ATOM   7866  O O   . GLN C 1 46  ? 127.125 117.872 141.871 1.00 26.57  ? 46  GLN C O   1 
ATOM   7867  C CB  . GLN C 1 46  ? 124.392 118.457 143.058 1.00 26.57  ? 46  GLN C CB  1 
ATOM   7868  C CG  . GLN C 1 46  ? 123.634 117.439 142.223 1.00 26.57  ? 46  GLN C CG  1 
ATOM   7869  C CD  . GLN C 1 46  ? 122.730 116.556 143.056 1.00 26.57  ? 46  GLN C CD  1 
ATOM   7870  O OE1 . GLN C 1 46  ? 122.090 117.017 143.998 1.00 26.57  ? 46  GLN C OE1 1 
ATOM   7871  N NE2 . GLN C 1 46  ? 122.669 115.277 142.709 1.00 26.57  ? 46  GLN C NE2 1 
ATOM   7872  N N   . ASN C 1 47  ? 126.684 115.896 142.873 1.00 28.29  ? 47  ASN C N   1 
ATOM   7873  C CA  . ASN C 1 47  ? 127.677 115.156 142.104 1.00 28.29  ? 47  ASN C CA  1 
ATOM   7874  C C   . ASN C 1 47  ? 127.111 113.897 141.456 1.00 28.29  ? 47  ASN C C   1 
ATOM   7875  O O   . ASN C 1 47  ? 127.869 112.965 141.172 1.00 28.29  ? 47  ASN C O   1 
ATOM   7876  C CB  . ASN C 1 47  ? 128.871 114.790 142.989 1.00 28.29  ? 47  ASN C CB  1 
ATOM   7877  C CG  . ASN C 1 47  ? 128.474 113.931 144.172 1.00 28.29  ? 47  ASN C CG  1 
ATOM   7878  O OD1 . ASN C 1 47  ? 127.443 114.161 144.801 1.00 28.29  ? 47  ASN C OD1 1 
ATOM   7879  N ND2 . ASN C 1 47  ? 129.292 112.933 144.481 1.00 28.29  ? 47  ASN C ND2 1 
ATOM   7880  N N   . SER C 1 48  ? 125.805 113.842 141.206 1.00 29.15  ? 48  SER C N   1 
ATOM   7881  C CA  . SER C 1 48  ? 125.217 112.651 140.612 1.00 29.15  ? 48  SER C CA  1 
ATOM   7882  C C   . SER C 1 48  ? 124.004 113.036 139.780 1.00 29.15  ? 48  SER C C   1 
ATOM   7883  O O   . SER C 1 48  ? 123.436 114.120 139.933 1.00 29.15  ? 48  SER C O   1 
ATOM   7884  C CB  . SER C 1 48  ? 124.828 111.623 141.682 1.00 29.15  ? 48  SER C CB  1 
ATOM   7885  O OG  . SER C 1 48  ? 123.945 112.185 142.635 1.00 29.15  ? 48  SER C OG  1 
ATOM   7886  N N   . SER C 1 49  ? 123.617 112.124 138.890 1.00 30.29  ? 49  SER C N   1 
ATOM   7887  C CA  . SER C 1 49  ? 122.447 112.297 138.044 1.00 30.29  ? 49  SER C CA  1 
ATOM   7888  C C   . SER C 1 49  ? 121.821 110.936 137.778 1.00 30.29  ? 49  SER C C   1 
ATOM   7889  O O   . SER C 1 49  ? 122.467 109.894 137.915 1.00 30.29  ? 49  SER C O   1 
ATOM   7890  C CB  . SER C 1 49  ? 122.800 112.988 136.721 1.00 30.29  ? 49  SER C CB  1 
ATOM   7891  O OG  . SER C 1 49  ? 121.669 113.063 135.873 1.00 30.29  ? 49  SER C OG  1 
ATOM   7892  N N   . THR C 1 50  ? 120.544 110.955 137.394 1.00 33.22  ? 50  THR C N   1 
ATOM   7893  C CA  . THR C 1 50  ? 119.824 109.725 137.090 1.00 33.22  ? 50  THR C CA  1 
ATOM   7894  C C   . THR C 1 50  ? 119.986 109.275 135.644 1.00 33.22  ? 50  THR C C   1 
ATOM   7895  O O   . THR C 1 50  ? 119.581 108.156 135.315 1.00 33.22  ? 50  THR C O   1 
ATOM   7896  C CB  . THR C 1 50  ? 118.335 109.893 137.403 1.00 33.22  ? 50  THR C CB  1 
ATOM   7897  O OG1 . THR C 1 50  ? 117.865 111.129 136.850 1.00 33.22  ? 50  THR C OG1 1 
ATOM   7898  C CG2 . THR C 1 50  ? 118.106 109.895 138.905 1.00 33.22  ? 50  THR C CG2 1 
ATOM   7899  N N   . GLY C 1 51  ? 120.565 110.106 134.781 1.00 31.67  ? 51  GLY C N   1 
ATOM   7900  C CA  . GLY C 1 51  ? 120.759 109.737 133.395 1.00 31.67  ? 51  GLY C CA  1 
ATOM   7901  C C   . GLY C 1 51  ? 119.562 109.934 132.495 1.00 31.67  ? 51  GLY C C   1 
ATOM   7902  O O   . GLY C 1 51  ? 119.571 109.434 131.366 1.00 31.67  ? 51  GLY C O   1 
ATOM   7903  N N   . LYS C 1 52  ? 118.534 110.644 132.952 1.00 31.99  ? 52  LYS C N   1 
ATOM   7904  C CA  . LYS C 1 52  ? 117.344 110.906 132.159 1.00 31.99  ? 52  LYS C CA  1 
ATOM   7905  C C   . LYS C 1 52  ? 117.108 112.408 132.088 1.00 31.99  ? 52  LYS C C   1 
ATOM   7906  O O   . LYS C 1 52  ? 117.550 113.167 132.953 1.00 31.99  ? 52  LYS C O   1 
ATOM   7907  C CB  . LYS C 1 52  ? 116.107 110.211 132.743 1.00 31.99  ? 52  LYS C CB  1 
ATOM   7908  C CG  . LYS C 1 52  ? 116.345 108.783 133.200 1.00 31.99  ? 52  LYS C CG  1 
ATOM   7909  C CD  . LYS C 1 52  ? 116.526 107.849 132.021 1.00 31.99  ? 52  LYS C CD  1 
ATOM   7910  C CE  . LYS C 1 52  ? 116.648 106.404 132.473 1.00 31.99  ? 52  LYS C CE  1 
ATOM   7911  N NZ  . LYS C 1 52  ? 117.955 106.141 133.136 1.00 31.99  ? 52  LYS C NZ  1 
ATOM   7912  N N   . ILE C 1 53  ? 116.401 112.830 131.044 1.00 30.28  ? 53  ILE C N   1 
ATOM   7913  C CA  . ILE C 1 53  ? 116.076 114.235 130.822 1.00 30.28  ? 53  ILE C CA  1 
ATOM   7914  C C   . ILE C 1 53  ? 114.583 114.419 131.052 1.00 30.28  ? 53  ILE C C   1 
ATOM   7915  O O   . ILE C 1 53  ? 113.761 113.755 130.410 1.00 30.28  ? 53  ILE C O   1 
ATOM   7916  C CB  . ILE C 1 53  ? 116.478 114.696 129.412 1.00 30.28  ? 53  ILE C CB  1 
ATOM   7917  C CG1 . ILE C 1 53  ? 117.996 114.630 129.241 1.00 30.28  ? 53  ILE C CG1 1 
ATOM   7918  C CG2 . ILE C 1 53  ? 115.977 116.104 129.149 1.00 30.28  ? 53  ILE C CG2 1 
ATOM   7919  C CD1 . ILE C 1 53  ? 118.459 114.859 127.821 1.00 30.28  ? 53  ILE C CD1 1 
ATOM   7920  N N   . CYS C 1 54  ? 114.235 115.318 131.970 1.00 35.31  ? 54  CYS C N   1 
ATOM   7921  C CA  . CYS C 1 54  ? 112.840 115.621 132.254 1.00 35.31  ? 54  CYS C CA  1 
ATOM   7922  C C   . CYS C 1 54  ? 112.255 116.516 131.170 1.00 35.31  ? 54  CYS C C   1 
ATOM   7923  O O   . CYS C 1 54  ? 112.869 117.505 130.762 1.00 35.31  ? 54  CYS C O   1 
ATOM   7924  C CB  . CYS C 1 54  ? 112.709 116.300 133.617 1.00 35.31  ? 54  CYS C CB  1 
ATOM   7925  S SG  . CYS C 1 54  ? 112.982 115.205 135.023 1.00 35.31  ? 54  CYS C SG  1 
ATOM   7926  N N   . ASN C 1 55  ? 111.055 116.168 130.709 1.00 35.32  ? 55  ASN C N   1 
ATOM   7927  C CA  . ASN C 1 55  ? 110.371 116.932 129.676 1.00 35.32  ? 55  ASN C CA  1 
ATOM   7928  C C   . ASN C 1 55  ? 109.457 118.008 130.248 1.00 35.32  ? 55  ASN C C   1 
ATOM   7929  O O   . ASN C 1 55  ? 108.702 118.627 129.493 1.00 35.32  ? 55  ASN C O   1 
ATOM   7930  C CB  . ASN C 1 55  ? 109.571 115.999 128.762 1.00 35.32  ? 55  ASN C CB  1 
ATOM   7931  C CG  . ASN C 1 55  ? 108.573 115.153 129.520 1.00 35.32  ? 55  ASN C CG  1 
ATOM   7932  O OD1 . ASN C 1 55  ? 108.949 114.293 130.311 1.00 35.32  ? 55  ASN C OD1 1 
ATOM   7933  N ND2 . ASN C 1 55  ? 107.290 115.390 129.277 1.00 35.32  ? 55  ASN C ND2 1 
ATOM   7934  N N   . ASN C 1 56  ? 109.496 118.231 131.561 1.00 34.27  ? 56  ASN C N   1 
ATOM   7935  C CA  . ASN C 1 56  ? 108.773 119.320 132.195 1.00 34.27  ? 56  ASN C CA  1 
ATOM   7936  C C   . ASN C 1 56  ? 109.715 120.084 133.115 1.00 34.27  ? 56  ASN C C   1 
ATOM   7937  O O   . ASN C 1 56  ? 110.605 119.482 133.726 1.00 34.27  ? 56  ASN C O   1 
ATOM   7938  C CB  . ASN C 1 56  ? 107.574 118.794 132.997 1.00 34.27  ? 56  ASN C CB  1 
ATOM   7939  C CG  . ASN C 1 56  ? 106.297 118.764 132.183 1.00 34.27  ? 56  ASN C CG  1 
ATOM   7940  O OD1 . ASN C 1 56  ? 105.849 119.790 131.673 1.00 34.27  ? 56  ASN C OD1 1 
ATOM   7941  N ND2 . ASN C 1 56  ? 105.703 117.584 132.058 1.00 34.27  ? 56  ASN C ND2 1 
ATOM   7942  N N   . PRO C 1 57  ? 109.550 121.411 133.241 1.00 31.76  ? 57  PRO C N   1 
ATOM   7943  C CA  . PRO C 1 57  ? 108.548 122.228 132.552 1.00 31.76  ? 57  PRO C CA  1 
ATOM   7944  C C   . PRO C 1 57  ? 109.010 122.759 131.195 1.00 31.76  ? 57  PRO C C   1 
ATOM   7945  O O   . PRO C 1 57  ? 108.236 123.426 130.511 1.00 31.76  ? 57  PRO C O   1 
ATOM   7946  C CB  . PRO C 1 57  ? 108.328 123.379 133.528 1.00 31.76  ? 57  PRO C CB  1 
ATOM   7947  C CG  . PRO C 1 57  ? 109.665 123.567 134.157 1.00 31.76  ? 57  PRO C CG  1 
ATOM   7948  C CD  . PRO C 1 57  ? 110.324 122.208 134.209 1.00 31.76  ? 57  PRO C CD  1 
ATOM   7949  N N   . HIS C 1 58  ? 110.251 122.470 130.816 1.00 30.34  ? 58  HIS C N   1 
ATOM   7950  C CA  . HIS C 1 58  ? 110.773 122.926 129.537 1.00 30.34  ? 58  HIS C CA  1 
ATOM   7951  C C   . HIS C 1 58  ? 110.316 122.005 128.413 1.00 30.34  ? 58  HIS C C   1 
ATOM   7952  O O   . HIS C 1 58  ? 110.145 120.798 128.601 1.00 30.34  ? 58  HIS C O   1 
ATOM   7953  C CB  . HIS C 1 58  ? 112.301 122.983 129.562 1.00 30.34  ? 58  HIS C CB  1 
ATOM   7954  C CG  . HIS C 1 58  ? 112.864 123.751 130.717 1.00 30.34  ? 58  HIS C CG  1 
ATOM   7955  N ND1 . HIS C 1 58  ? 112.678 125.107 130.870 1.00 30.34  ? 58  HIS C ND1 1 
ATOM   7956  C CD2 . HIS C 1 58  ? 113.620 123.354 131.767 1.00 30.34  ? 58  HIS C CD2 1 
ATOM   7957  C CE1 . HIS C 1 58  ? 113.289 125.512 131.969 1.00 30.34  ? 58  HIS C CE1 1 
ATOM   7958  N NE2 . HIS C 1 58  ? 113.869 124.467 132.531 1.00 30.34  ? 58  HIS C NE2 1 
ATOM   7959  N N   . LYS C 1 59  ? 110.126 122.587 127.232 1.00 27.52  ? 59  LYS C N   1 
ATOM   7960  C CA  . LYS C 1 59  ? 109.742 121.818 126.053 1.00 27.52  ? 59  LYS C CA  1 
ATOM   7961  C C   . LYS C 1 59  ? 111.003 121.282 125.387 1.00 27.52  ? 59  LYS C C   1 
ATOM   7962  O O   . LYS C 1 59  ? 111.811 122.051 124.859 1.00 27.52  ? 59  LYS C O   1 
ATOM   7963  C CB  . LYS C 1 59  ? 108.934 122.678 125.086 1.00 27.52  ? 59  LYS C CB  1 
ATOM   7964  C CG  . LYS C 1 59  ? 108.413 121.913 123.886 1.00 27.52  ? 59  LYS C CG  1 
ATOM   7965  C CD  . LYS C 1 59  ? 107.675 122.821 122.920 1.00 27.52  ? 59  LYS C CD  1 
ATOM   7966  C CE  . LYS C 1 59  ? 106.923 122.008 121.880 1.00 27.52  ? 59  LYS C CE  1 
ATOM   7967  N NZ  . LYS C 1 59  ? 107.827 121.076 121.152 1.00 27.52  ? 59  LYS C NZ  1 
ATOM   7968  N N   . VAL C 1 60  ? 111.170 119.963 125.407 1.00 27.33  ? 60  VAL C N   1 
ATOM   7969  C CA  . VAL C 1 60  ? 112.356 119.301 124.880 1.00 27.33  ? 60  VAL C CA  1 
ATOM   7970  C C   . VAL C 1 60  ? 111.970 118.572 123.602 1.00 27.33  ? 60  VAL C C   1 
ATOM   7971  O O   . VAL C 1 60  ? 111.015 117.785 123.593 1.00 27.33  ? 60  VAL C O   1 
ATOM   7972  C CB  . VAL C 1 60  ? 112.960 118.330 125.909 1.00 27.33  ? 60  VAL C CB  1 
ATOM   7973  C CG1 . VAL C 1 60  ? 114.218 117.689 125.358 1.00 27.33  ? 60  VAL C CG1 1 
ATOM   7974  C CG2 . VAL C 1 60  ? 113.253 119.053 127.211 1.00 27.33  ? 60  VAL C CG2 1 
ATOM   7975  N N   . LEU C 1 61  ? 112.707 118.834 122.527 1.00 25.82  ? 61  LEU C N   1 
ATOM   7976  C CA  . LEU C 1 61  ? 112.475 118.204 121.234 1.00 25.82  ? 61  LEU C CA  1 
ATOM   7977  C C   . LEU C 1 61  ? 113.649 117.288 120.919 1.00 25.82  ? 61  LEU C C   1 
ATOM   7978  O O   . LEU C 1 61  ? 114.800 117.736 120.893 1.00 25.82  ? 61  LEU C O   1 
ATOM   7979  C CB  . LEU C 1 61  ? 112.297 119.254 120.137 1.00 25.82  ? 61  LEU C CB  1 
ATOM   7980  C CG  . LEU C 1 61  ? 111.967 118.740 118.735 1.00 25.82  ? 61  LEU C CG  1 
ATOM   7981  C CD1 . LEU C 1 61  ? 110.630 118.024 118.726 1.00 25.82  ? 61  LEU C CD1 1 
ATOM   7982  C CD2 . LEU C 1 61  ? 111.967 119.881 117.734 1.00 25.82  ? 61  LEU C CD2 1 
ATOM   7983  N N   . ASP C 1 62  ? 113.355 116.014 120.679 1.00 29.06  ? 62  ASP C N   1 
ATOM   7984  C CA  . ASP C 1 62  ? 114.379 115.018 120.391 1.00 29.06  ? 62  ASP C CA  1 
ATOM   7985  C C   . ASP C 1 62  ? 114.697 115.038 118.901 1.00 29.06  ? 62  ASP C C   1 
ATOM   7986  O O   . ASP C 1 62  ? 113.812 114.815 118.069 1.00 29.06  ? 62  ASP C O   1 
ATOM   7987  C CB  . ASP C 1 62  ? 113.913 113.629 120.824 1.00 29.06  ? 62  ASP C CB  1 
ATOM   7988  C CG  . ASP C 1 62  ? 115.038 112.615 120.836 1.00 29.06  ? 62  ASP C CG  1 
ATOM   7989  O OD1 . ASP C 1 62  ? 116.209 113.021 120.699 1.00 29.06  ? 62  ASP C OD1 1 
ATOM   7990  O OD2 . ASP C 1 62  ? 114.750 111.409 120.982 1.00 29.06  ? 62  ASP C OD2 1 
ATOM   7991  N N   . GLY C 1 63  ? 115.963 115.300 118.568 1.00 28.86  ? 63  GLY C N   1 
ATOM   7992  C CA  . GLY C 1 63  ? 116.371 115.331 117.176 1.00 28.86  ? 63  GLY C CA  1 
ATOM   7993  C C   . GLY C 1 63  ? 116.459 113.974 116.516 1.00 28.86  ? 63  GLY C C   1 
ATOM   7994  O O   . GLY C 1 63  ? 116.416 113.896 115.285 1.00 28.86  ? 63  GLY C O   1 
ATOM   7995  N N   . ARG C 1 64  ? 116.584 112.908 117.308 1.00 31.20  ? 64  ARG C N   1 
ATOM   7996  C CA  . ARG C 1 64  ? 116.678 111.542 116.805 1.00 31.20  ? 64  ARG C CA  1 
ATOM   7997  C C   . ARG C 1 64  ? 117.864 111.383 115.862 1.00 31.20  ? 64  ARG C C   1 
ATOM   7998  O O   . ARG C 1 64  ? 119.017 111.535 116.277 1.00 31.20  ? 64  ARG C O   1 
ATOM   7999  C CB  . ARG C 1 64  ? 115.375 111.137 116.112 1.00 31.20  ? 64  ARG C CB  1 
ATOM   8000  C CG  . ARG C 1 64  ? 114.363 110.494 117.042 1.00 31.20  ? 64  ARG C CG  1 
ATOM   8001  C CD  . ARG C 1 64  ? 112.965 110.543 116.457 1.00 31.20  ? 64  ARG C CD  1 
ATOM   8002  N NE  . ARG C 1 64  ? 112.274 111.773 116.822 1.00 31.20  ? 64  ARG C NE  1 
ATOM   8003  C CZ  . ARG C 1 64  ? 111.533 111.921 117.911 1.00 31.20  ? 64  ARG C CZ  1 
ATOM   8004  N NH1 . ARG C 1 64  ? 111.353 110.927 118.765 1.00 31.20  ? 64  ARG C NH1 1 
ATOM   8005  N NH2 . ARG C 1 64  ? 110.958 113.096 118.150 1.00 31.20  ? 64  ARG C NH2 1 
ATOM   8006  N N   . ASP C 1 65  ? 117.596 111.081 114.592 1.00 31.78  ? 65  ASP C N   1 
ATOM   8007  C CA  . ASP C 1 65  ? 118.641 110.892 113.596 1.00 31.78  ? 65  ASP C CA  1 
ATOM   8008  C C   . ASP C 1 65  ? 118.816 112.110 112.697 1.00 31.78  ? 65  ASP C C   1 
ATOM   8009  O O   . ASP C 1 65  ? 119.331 111.980 111.582 1.00 31.78  ? 65  ASP C O   1 
ATOM   8010  C CB  . ASP C 1 65  ? 118.348 109.649 112.754 1.00 31.78  ? 65  ASP C CB  1 
ATOM   8011  C CG  . ASP C 1 65  ? 116.948 109.654 112.176 1.00 31.78  ? 65  ASP C CG  1 
ATOM   8012  O OD1 . ASP C 1 65  ? 116.106 110.441 112.658 1.00 31.78  ? 65  ASP C OD1 1 
ATOM   8013  O OD2 . ASP C 1 65  ? 116.687 108.871 111.239 1.00 31.78  ? 65  ASP C OD2 1 
ATOM   8014  N N   . CYS C 1 66  ? 118.406 113.287 113.161 1.00 28.86  ? 66  CYS C N   1 
ATOM   8015  C CA  . CYS C 1 66  ? 118.475 114.514 112.383 1.00 28.86  ? 66  CYS C CA  1 
ATOM   8016  C C   . CYS C 1 66  ? 119.195 115.598 113.171 1.00 28.86  ? 66  CYS C C   1 
ATOM   8017  O O   . CYS C 1 66  ? 119.124 115.636 114.403 1.00 28.86  ? 66  CYS C O   1 
ATOM   8018  C CB  . CYS C 1 66  ? 117.076 115.004 112.004 1.00 28.86  ? 66  CYS C CB  1 
ATOM   8019  S SG  . CYS C 1 66  ? 116.255 114.019 110.740 1.00 28.86  ? 66  CYS C SG  1 
ATOM   8020  N N   . THR C 1 67  ? 119.891 116.473 112.453 1.00 24.09  ? 67  THR C N   1 
ATOM   8021  C CA  . THR C 1 67  ? 120.458 117.675 113.039 1.00 24.09  ? 67  THR C CA  1 
ATOM   8022  C C   . THR C 1 67  ? 119.536 118.863 112.779 1.00 24.09  ? 67  THR C C   1 
ATOM   8023  O O   . THR C 1 67  ? 118.565 118.777 112.026 1.00 24.09  ? 67  THR C O   1 
ATOM   8024  C CB  . THR C 1 67  ? 121.855 117.949 112.482 1.00 24.09  ? 67  THR C CB  1 
ATOM   8025  O OG1 . THR C 1 67  ? 121.790 118.077 111.057 1.00 24.09  ? 67  THR C OG1 1 
ATOM   8026  C CG2 . THR C 1 67  ? 122.804 116.819 112.839 1.00 24.09  ? 67  THR C CG2 1 
ATOM   8027  N N   . LEU C 1 68  ? 119.847 119.988 113.424 1.00 21.87  ? 68  LEU C N   1 
ATOM   8028  C CA  . LEU C 1 68  ? 119.007 121.172 113.275 1.00 21.87  ? 68  LEU C CA  1 
ATOM   8029  C C   . LEU C 1 68  ? 119.121 121.761 111.873 1.00 21.87  ? 68  LEU C C   1 
ATOM   8030  O O   . LEU C 1 68  ? 118.123 122.213 111.302 1.00 21.87  ? 68  LEU C O   1 
ATOM   8031  C CB  . LEU C 1 68  ? 119.377 122.210 114.332 1.00 21.87  ? 68  LEU C CB  1 
ATOM   8032  C CG  . LEU C 1 68  ? 118.434 123.404 114.481 1.00 21.87  ? 68  LEU C CG  1 
ATOM   8033  C CD1 . LEU C 1 68  ? 117.010 122.936 114.724 1.00 21.87  ? 68  LEU C CD1 1 
ATOM   8034  C CD2 . LEU C 1 68  ? 118.900 124.304 115.607 1.00 21.87  ? 68  LEU C CD2 1 
ATOM   8035  N N   . ILE C 1 69  ? 120.326 121.756 111.300 1.00 22.31  ? 69  ILE C N   1 
ATOM   8036  C CA  . ILE C 1 69  ? 120.514 122.302 109.959 1.00 22.31  ? 69  ILE C CA  1 
ATOM   8037  C C   . ILE C 1 69  ? 119.850 121.408 108.918 1.00 22.31  ? 69  ILE C C   1 
ATOM   8038  O O   . ILE C 1 69  ? 119.233 121.896 107.964 1.00 22.31  ? 69  ILE C O   1 
ATOM   8039  C CB  . ILE C 1 69  ? 122.013 122.498 109.671 1.00 22.31  ? 69  ILE C CB  1 
ATOM   8040  C CG1 . ILE C 1 69  ? 122.633 123.439 110.707 1.00 22.31  ? 69  ILE C CG1 1 
ATOM   8041  C CG2 . ILE C 1 69  ? 122.225 123.039 108.267 1.00 22.31  ? 69  ILE C CG2 1 
ATOM   8042  C CD1 . ILE C 1 69  ? 122.171 124.872 110.593 1.00 22.31  ? 69  ILE C CD1 1 
ATOM   8043  N N   . ASP C 1 70  ? 119.966 120.088 109.081 1.00 24.31  ? 70  ASP C N   1 
ATOM   8044  C CA  . ASP C 1 70  ? 119.311 119.166 108.159 1.00 24.31  ? 70  ASP C CA  1 
ATOM   8045  C C   . ASP C 1 70  ? 117.795 119.287 108.241 1.00 24.31  ? 70  ASP C C   1 
ATOM   8046  O O   . ASP C 1 70  ? 117.103 119.224 107.219 1.00 24.31  ? 70  ASP C O   1 
ATOM   8047  C CB  . ASP C 1 70  ? 119.749 117.732 108.452 1.00 24.31  ? 70  ASP C CB  1 
ATOM   8048  C CG  . ASP C 1 70  ? 120.982 117.327 107.671 1.00 24.31  ? 70  ASP C CG  1 
ATOM   8049  O OD1 . ASP C 1 70  ? 121.104 117.727 106.495 1.00 24.31  ? 70  ASP C OD1 1 
ATOM   8050  O OD2 . ASP C 1 70  ? 121.832 116.608 108.234 1.00 24.31  ? 70  ASP C OD2 1 
ATOM   8051  N N   . ALA C 1 71  ? 117.260 119.451 109.454 1.00 24.86  ? 71  ALA C N   1 
ATOM   8052  C CA  . ALA C 1 71  ? 115.821 119.624 109.614 1.00 24.86  ? 71  ALA C CA  1 
ATOM   8053  C C   . ALA C 1 71  ? 115.351 120.965 109.068 1.00 24.86  ? 71  ALA C C   1 
ATOM   8054  O O   . ALA C 1 71  ? 114.218 121.073 108.589 1.00 24.86  ? 71  ALA C O   1 
ATOM   8055  C CB  . ALA C 1 71  ? 115.436 119.489 111.086 1.00 24.86  ? 71  ALA C CB  1 
ATOM   8056  N N   . MET C 1 72  ? 116.198 121.994 109.139 1.00 23.01  ? 72  MET C N   1 
ATOM   8057  C CA  . MET C 1 72  ? 115.822 123.297 108.603 1.00 23.01  ? 72  MET C CA  1 
ATOM   8058  C C   . MET C 1 72  ? 115.856 123.301 107.080 1.00 23.01  ? 72  MET C C   1 
ATOM   8059  O O   . MET C 1 72  ? 114.998 123.916 106.437 1.00 23.01  ? 72  MET C O   1 
ATOM   8060  C CB  . MET C 1 72  ? 116.745 124.377 109.170 1.00 23.01  ? 72  MET C CB  1 
ATOM   8061  C CG  . MET C 1 72  ? 116.500 125.770 108.619 1.00 23.01  ? 72  MET C CG  1 
ATOM   8062  S SD  . MET C 1 72  ? 117.986 126.789 108.623 1.00 23.01  ? 72  MET C SD  1 
ATOM   8063  C CE  . MET C 1 72  ? 119.040 125.863 107.512 1.00 23.01  ? 72  MET C CE  1 
ATOM   8064  N N   . LEU C 1 73  ? 116.838 122.619 106.484 1.00 22.84  ? 73  LEU C N   1 
ATOM   8065  C CA  . LEU C 1 73  ? 116.954 122.604 105.030 1.00 22.84  ? 73  LEU C CA  1 
ATOM   8066  C C   . LEU C 1 73  ? 115.822 121.824 104.372 1.00 22.84  ? 73  LEU C C   1 
ATOM   8067  O O   . LEU C 1 73  ? 115.382 122.186 103.276 1.00 22.84  ? 73  LEU C O   1 
ATOM   8068  C CB  . LEU C 1 73  ? 118.304 122.023 104.614 1.00 22.84  ? 73  LEU C CB  1 
ATOM   8069  C CG  . LEU C 1 73  ? 119.507 122.960 104.728 1.00 22.84  ? 73  LEU C CG  1 
ATOM   8070  C CD1 . LEU C 1 73  ? 120.785 122.239 104.348 1.00 22.84  ? 73  LEU C CD1 1 
ATOM   8071  C CD2 . LEU C 1 73  ? 119.307 124.193 103.865 1.00 22.84  ? 73  LEU C CD2 1 
ATOM   8072  N N   . GLY C 1 74  ? 115.338 120.765 105.015 1.00 24.35  ? 74  GLY C N   1 
ATOM   8073  C CA  . GLY C 1 74  ? 114.293 119.951 104.426 1.00 24.35  ? 74  GLY C CA  1 
ATOM   8074  C C   . GLY C 1 74  ? 114.766 118.592 103.955 1.00 24.35  ? 74  GLY C C   1 
ATOM   8075  O O   . GLY C 1 74  ? 114.368 118.126 102.884 1.00 24.35  ? 74  GLY C O   1 
ATOM   8076  N N   . ASP C 1 75  ? 115.627 117.955 104.743 1.00 27.64  ? 75  ASP C N   1 
ATOM   8077  C CA  . ASP C 1 75  ? 116.099 116.619 104.413 1.00 27.64  ? 75  ASP C CA  1 
ATOM   8078  C C   . ASP C 1 75  ? 114.917 115.652 104.361 1.00 27.64  ? 75  ASP C C   1 
ATOM   8079  O O   . ASP C 1 75  ? 114.017 115.729 105.206 1.00 27.64  ? 75  ASP C O   1 
ATOM   8080  C CB  . ASP C 1 75  ? 117.124 116.157 105.451 1.00 27.64  ? 75  ASP C CB  1 
ATOM   8081  C CG  . ASP C 1 75  ? 118.104 115.138 104.903 1.00 27.64  ? 75  ASP C CG  1 
ATOM   8082  O OD1 . ASP C 1 75  ? 117.684 114.008 104.582 1.00 27.64  ? 75  ASP C OD1 1 
ATOM   8083  O OD2 . ASP C 1 75  ? 119.303 115.467 104.799 1.00 27.64  ? 75  ASP C OD2 1 
ATOM   8084  N N   . PRO C 1 76  ? 114.876 114.745 103.378 1.00 29.56  ? 76  PRO C N   1 
ATOM   8085  C CA  . PRO C 1 76  ? 113.711 113.850 103.257 1.00 29.56  ? 76  PRO C CA  1 
ATOM   8086  C C   . PRO C 1 76  ? 113.426 113.028 104.501 1.00 29.56  ? 76  PRO C C   1 
ATOM   8087  O O   . PRO C 1 76  ? 112.255 112.816 104.837 1.00 29.56  ? 76  PRO C O   1 
ATOM   8088  C CB  . PRO C 1 76  ? 114.088 112.957 102.069 1.00 29.56  ? 76  PRO C CB  1 
ATOM   8089  C CG  . PRO C 1 76  ? 114.997 113.790 101.257 1.00 29.56  ? 76  PRO C CG  1 
ATOM   8090  C CD  . PRO C 1 76  ? 115.774 114.642 102.217 1.00 29.56  ? 76  PRO C CD  1 
ATOM   8091  N N   . HIS C 1 77  ? 114.458 112.557 105.198 1.00 29.54  ? 77  HIS C N   1 
ATOM   8092  C CA  . HIS C 1 77  ? 114.241 111.792 106.418 1.00 29.54  ? 77  HIS C CA  1 
ATOM   8093  C C   . HIS C 1 77  ? 114.060 112.682 107.639 1.00 29.54  ? 77  HIS C C   1 
ATOM   8094  O O   . HIS C 1 77  ? 113.866 112.163 108.743 1.00 29.54  ? 77  HIS C O   1 
ATOM   8095  C CB  . HIS C 1 77  ? 115.392 110.800 106.632 1.00 29.54  ? 77  HIS C CB  1 
ATOM   8096  C CG  . HIS C 1 77  ? 116.572 111.370 107.357 1.00 29.54  ? 77  HIS C CG  1 
ATOM   8097  N ND1 . HIS C 1 77  ? 117.502 112.183 106.745 1.00 29.54  ? 77  HIS C ND1 1 
ATOM   8098  C CD2 . HIS C 1 77  ? 116.990 111.220 108.636 1.00 29.54  ? 77  HIS C CD2 1 
ATOM   8099  C CE1 . HIS C 1 77  ? 118.432 112.521 107.619 1.00 29.54  ? 77  HIS C CE1 1 
ATOM   8100  N NE2 . HIS C 1 77  ? 118.145 111.949 108.774 1.00 29.54  ? 77  HIS C NE2 1 
ATOM   8101  N N   . CYS C 1 78  ? 114.110 114.002 107.463 1.00 29.49  ? 78  CYS C N   1 
ATOM   8102  C CA  . CYS C 1 78  ? 113.842 114.967 108.521 1.00 29.49  ? 78  CYS C CA  1 
ATOM   8103  C C   . CYS C 1 78  ? 112.581 115.777 108.238 1.00 29.49  ? 78  CYS C C   1 
ATOM   8104  O O   . CYS C 1 78  ? 112.473 116.933 108.652 1.00 29.49  ? 78  CYS C O   1 
ATOM   8105  C CB  . CYS C 1 78  ? 115.037 115.899 108.707 1.00 29.49  ? 78  CYS C CB  1 
ATOM   8106  S SG  . CYS C 1 78  ? 116.596 115.060 109.031 1.00 29.49  ? 78  CYS C SG  1 
ATOM   8107  N N   . ASP C 1 79  ? 111.620 115.185 107.528 1.00 29.82  ? 79  ASP C N   1 
ATOM   8108  C CA  . ASP C 1 79  ? 110.410 115.894 107.136 1.00 29.82  ? 79  ASP C CA  1 
ATOM   8109  C C   . ASP C 1 79  ? 109.381 115.984 108.253 1.00 29.82  ? 79  ASP C C   1 
ATOM   8110  O O   . ASP C 1 79  ? 108.404 116.726 108.112 1.00 29.82  ? 79  ASP C O   1 
ATOM   8111  C CB  . ASP C 1 79  ? 109.777 115.223 105.915 1.00 29.82  ? 79  ASP C CB  1 
ATOM   8112  C CG  . ASP C 1 79  ? 110.341 115.741 104.607 1.00 29.82  ? 79  ASP C CG  1 
ATOM   8113  O OD1 . ASP C 1 79  ? 110.946 116.833 104.607 1.00 29.82  ? 79  ASP C OD1 1 
ATOM   8114  O OD2 . ASP C 1 79  ? 110.177 115.056 103.576 1.00 29.82  ? 79  ASP C OD2 1 
ATOM   8115  N N   . VAL C 1 80  ? 109.570 115.249 109.351 1.00 29.80  ? 80  VAL C N   1 
ATOM   8116  C CA  . VAL C 1 80  ? 108.643 115.322 110.478 1.00 29.80  ? 80  VAL C CA  1 
ATOM   8117  C C   . VAL C 1 80  ? 108.904 116.536 111.355 1.00 29.80  ? 80  VAL C C   1 
ATOM   8118  O O   . VAL C 1 80  ? 108.085 116.853 112.226 1.00 29.80  ? 80  VAL C O   1 
ATOM   8119  C CB  . VAL C 1 80  ? 108.727 114.019 111.297 1.00 29.80  ? 80  VAL C CB  1 
ATOM   8120  C CG1 . VAL C 1 80  ? 110.046 113.940 112.053 1.00 29.80  ? 80  VAL C CG1 1 
ATOM   8121  C CG2 . VAL C 1 80  ? 107.530 113.867 112.230 1.00 29.80  ? 80  VAL C CG2 1 
ATOM   8122  N N   . PHE C 1 81  ? 110.011 117.244 111.130 1.00 27.11  ? 81  PHE C N   1 
ATOM   8123  C CA  . PHE C 1 81  ? 110.391 118.398 111.932 1.00 27.11  ? 81  PHE C CA  1 
ATOM   8124  C C   . PHE C 1 81  ? 109.964 119.717 111.297 1.00 27.11  ? 81  PHE C C   1 
ATOM   8125  O O   . PHE C 1 81  ? 110.501 120.771 111.652 1.00 27.11  ? 81  PHE C O   1 
ATOM   8126  C CB  . PHE C 1 81  ? 111.900 118.393 112.175 1.00 27.11  ? 81  PHE C CB  1 
ATOM   8127  C CG  . PHE C 1 81  ? 112.360 117.298 113.090 1.00 27.11  ? 81  PHE C CG  1 
ATOM   8128  C CD1 . PHE C 1 81  ? 112.222 117.419 114.461 1.00 27.11  ? 81  PHE C CD1 1 
ATOM   8129  C CD2 . PHE C 1 81  ? 112.926 116.143 112.579 1.00 27.11  ? 81  PHE C CD2 1 
ATOM   8130  C CE1 . PHE C 1 81  ? 112.641 116.413 115.304 1.00 27.11  ? 81  PHE C CE1 1 
ATOM   8131  C CE2 . PHE C 1 81  ? 113.347 115.133 113.418 1.00 27.11  ? 81  PHE C CE2 1 
ATOM   8132  C CZ  . PHE C 1 81  ? 113.205 115.268 114.782 1.00 27.11  ? 81  PHE C CZ  1 
ATOM   8133  N N   . GLN C 1 82  ? 109.014 119.682 110.368 1.00 27.85  ? 82  GLN C N   1 
ATOM   8134  C CA  . GLN C 1 82  ? 108.552 120.903 109.724 1.00 27.85  ? 82  GLN C CA  1 
ATOM   8135  C C   . GLN C 1 82  ? 107.643 121.685 110.664 1.00 27.85  ? 82  GLN C C   1 
ATOM   8136  O O   . GLN C 1 82  ? 106.713 121.124 111.252 1.00 27.85  ? 82  GLN C O   1 
ATOM   8137  C CB  . GLN C 1 82  ? 107.814 120.573 108.428 1.00 27.85  ? 82  GLN C CB  1 
ATOM   8138  C CG  . GLN C 1 82  ? 108.722 120.169 107.281 1.00 27.85  ? 82  GLN C CG  1 
ATOM   8139  C CD  . GLN C 1 82  ? 107.961 119.937 105.992 1.00 27.85  ? 82  GLN C CD  1 
ATOM   8140  O OE1 . GLN C 1 82  ? 106.732 119.885 105.985 1.00 27.85  ? 82  GLN C OE1 1 
ATOM   8141  N NE2 . GLN C 1 82  ? 108.689 119.795 104.893 1.00 27.85  ? 82  GLN C NE2 1 
ATOM   8142  N N   . ASP C 1 83  ? 107.917 122.985 110.801 1.00 28.11  ? 83  ASP C N   1 
ATOM   8143  C CA  . ASP C 1 83  ? 107.124 123.885 111.640 1.00 28.11  ? 83  ASP C CA  1 
ATOM   8144  C C   . ASP C 1 83  ? 107.093 123.406 113.091 1.00 28.11  ? 83  ASP C C   1 
ATOM   8145  O O   . ASP C 1 83  ? 106.032 123.167 113.669 1.00 28.11  ? 83  ASP C O   1 
ATOM   8146  C CB  . ASP C 1 83  ? 105.707 124.046 111.083 1.00 28.11  ? 83  ASP C CB  1 
ATOM   8147  C CG  . ASP C 1 83  ? 105.675 124.827 109.783 1.00 28.11  ? 83  ASP C CG  1 
ATOM   8148  O OD1 . ASP C 1 83  ? 106.041 126.019 109.793 1.00 28.11  ? 83  ASP C OD1 1 
ATOM   8149  O OD2 . ASP C 1 83  ? 105.283 124.248 108.749 1.00 28.11  ? 83  ASP C OD2 1 
ATOM   8150  N N   . GLU C 1 84  ? 108.275 123.270 113.682 1.00 28.10  ? 84  GLU C N   1 
ATOM   8151  C CA  . GLU C 1 84  ? 108.417 122.758 115.036 1.00 28.10  ? 84  GLU C CA  1 
ATOM   8152  C C   . GLU C 1 84  ? 108.844 123.861 115.998 1.00 28.10  ? 84  GLU C C   1 
ATOM   8153  O O   . GLU C 1 84  ? 109.447 124.864 115.609 1.00 28.10  ? 84  GLU C O   1 
ATOM   8154  C CB  . GLU C 1 84  ? 109.429 121.611 115.077 1.00 28.10  ? 84  GLU C CB  1 
ATOM   8155  C CG  . GLU C 1 84  ? 108.852 120.257 114.703 1.00 28.10  ? 84  GLU C CG  1 
ATOM   8156  C CD  . GLU C 1 84  ? 108.220 119.538 115.879 1.00 28.10  ? 84  GLU C CD  1 
ATOM   8157  O OE1 . GLU C 1 84  ? 107.996 120.180 116.926 1.00 28.10  ? 84  GLU C OE1 1 
ATOM   8158  O OE2 . GLU C 1 84  ? 107.948 118.326 115.756 1.00 28.10  ? 84  GLU C OE2 1 
ATOM   8159  N N   . LYS C 1 85  ? 108.520 123.655 117.273 1.00 26.25  ? 85  LYS C N   1 
ATOM   8160  C CA  . LYS C 1 85  ? 108.872 124.575 118.343 1.00 26.25  ? 85  LYS C CA  1 
ATOM   8161  C C   . LYS C 1 85  ? 109.630 123.817 119.421 1.00 26.25  ? 85  LYS C C   1 
ATOM   8162  O O   . LYS C 1 85  ? 109.396 122.626 119.641 1.00 26.25  ? 85  LYS C O   1 
ATOM   8163  C CB  . LYS C 1 85  ? 107.630 125.240 118.960 1.00 26.25  ? 85  LYS C CB  1 
ATOM   8164  C CG  . LYS C 1 85  ? 107.034 126.373 118.141 1.00 26.25  ? 85  LYS C CG  1 
ATOM   8165  C CD  . LYS C 1 85  ? 106.158 125.845 117.016 1.00 26.25  ? 85  LYS C CD  1 
ATOM   8166  C CE  . LYS C 1 85  ? 105.537 126.976 116.217 1.00 26.25  ? 85  LYS C CE  1 
ATOM   8167  N NZ  . LYS C 1 85  ? 104.828 126.473 115.009 1.00 26.25  ? 85  LYS C NZ  1 
ATOM   8168  N N   . TRP C 1 86  ? 110.541 124.514 120.094 1.00 22.36  ? 86  TRP C N   1 
ATOM   8169  C CA  . TRP C 1 86  ? 111.313 123.888 121.157 1.00 22.36  ? 86  TRP C CA  1 
ATOM   8170  C C   . TRP C 1 86  ? 111.837 124.958 122.101 1.00 22.36  ? 86  TRP C C   1 
ATOM   8171  O O   . TRP C 1 86  ? 112.001 126.121 121.725 1.00 22.36  ? 86  TRP C O   1 
ATOM   8172  C CB  . TRP C 1 86  ? 112.480 123.064 120.600 1.00 22.36  ? 86  TRP C CB  1 
ATOM   8173  C CG  . TRP C 1 86  ? 113.506 123.885 119.873 1.00 22.36  ? 86  TRP C CG  1 
ATOM   8174  C CD1 . TRP C 1 86  ? 114.569 124.543 120.420 1.00 22.36  ? 86  TRP C CD1 1 
ATOM   8175  C CD2 . TRP C 1 86  ? 113.568 124.131 118.464 1.00 22.36  ? 86  TRP C CD2 1 
ATOM   8176  N NE1 . TRP C 1 86  ? 115.284 125.186 119.443 1.00 22.36  ? 86  TRP C NE1 1 
ATOM   8177  C CE2 . TRP C 1 86  ? 114.691 124.946 118.231 1.00 22.36  ? 86  TRP C CE2 1 
ATOM   8178  C CE3 . TRP C 1 86  ? 112.781 123.741 117.377 1.00 22.36  ? 86  TRP C CE3 1 
ATOM   8179  C CZ2 . TRP C 1 86  ? 115.045 125.381 116.957 1.00 22.36  ? 86  TRP C CZ2 1 
ATOM   8180  C CZ3 . TRP C 1 86  ? 113.134 124.172 116.116 1.00 22.36  ? 86  TRP C CZ3 1 
ATOM   8181  C CH2 . TRP C 1 86  ? 114.256 124.983 115.916 1.00 22.36  ? 86  TRP C CH2 1 
ATOM   8182  N N   . ASP C 1 87  ? 112.093 124.542 123.339 1.00 24.23  ? 87  ASP C N   1 
ATOM   8183  C CA  . ASP C 1 87  ? 112.900 125.305 124.280 1.00 24.23  ? 87  ASP C CA  1 
ATOM   8184  C C   . ASP C 1 87  ? 114.340 124.819 124.316 1.00 24.23  ? 87  ASP C C   1 
ATOM   8185  O O   . ASP C 1 87  ? 115.262 125.623 124.464 1.00 24.23  ? 87  ASP C O   1 
ATOM   8186  C CB  . ASP C 1 87  ? 112.300 125.230 125.687 1.00 24.23  ? 87  ASP C CB  1 
ATOM   8187  C CG  . ASP C 1 87  ? 111.183 126.229 125.898 1.00 24.23  ? 87  ASP C CG  1 
ATOM   8188  O OD1 . ASP C 1 87  ? 111.276 127.350 125.357 1.00 24.23  ? 87  ASP C OD1 1 
ATOM   8189  O OD2 . ASP C 1 87  ? 110.211 125.896 126.607 1.00 24.23  ? 87  ASP C OD2 1 
ATOM   8190  N N   . LEU C 1 88  ? 114.544 123.511 124.180 1.00 22.69  ? 88  LEU C N   1 
ATOM   8191  C CA  . LEU C 1 88  ? 115.869 122.921 124.061 1.00 22.69  ? 88  LEU C CA  1 
ATOM   8192  C C   . LEU C 1 88  ? 115.827 121.850 122.985 1.00 22.69  ? 88  LEU C C   1 
ATOM   8193  O O   . LEU C 1 88  ? 114.975 120.959 123.027 1.00 22.69  ? 88  LEU C O   1 
ATOM   8194  C CB  . LEU C 1 88  ? 116.334 122.323 125.393 1.00 22.69  ? 88  LEU C CB  1 
ATOM   8195  C CG  . LEU C 1 88  ? 117.754 121.755 125.434 1.00 22.69  ? 88  LEU C CG  1 
ATOM   8196  C CD1 . LEU C 1 88  ? 118.784 122.868 125.497 1.00 22.69  ? 88  LEU C CD1 1 
ATOM   8197  C CD2 . LEU C 1 88  ? 117.912 120.807 126.608 1.00 22.69  ? 88  LEU C CD2 1 
ATOM   8198  N N   . PHE C 1 89  ? 116.738 121.945 122.022 1.00 22.36  ? 89  PHE C N   1 
ATOM   8199  C CA  . PHE C 1 89  ? 116.890 120.947 120.972 1.00 22.36  ? 89  PHE C CA  1 
ATOM   8200  C C   . PHE C 1 89  ? 118.024 120.006 121.352 1.00 22.36  ? 89  PHE C C   1 
ATOM   8201  O O   . PHE C 1 89  ? 119.120 120.459 121.698 1.00 22.36  ? 89  PHE C O   1 
ATOM   8202  C CB  . PHE C 1 89  ? 117.172 121.614 119.624 1.00 22.36  ? 89  PHE C CB  1 
ATOM   8203  C CG  . PHE C 1 89  ? 117.006 120.700 118.442 1.00 22.36  ? 89  PHE C CG  1 
ATOM   8204  C CD1 . PHE C 1 89  ? 118.057 119.909 118.006 1.00 22.36  ? 89  PHE C CD1 1 
ATOM   8205  C CD2 . PHE C 1 89  ? 115.804 120.640 117.760 1.00 22.36  ? 89  PHE C CD2 1 
ATOM   8206  C CE1 . PHE C 1 89  ? 117.908 119.071 116.920 1.00 22.36  ? 89  PHE C CE1 1 
ATOM   8207  C CE2 . PHE C 1 89  ? 115.650 119.803 116.673 1.00 22.36  ? 89  PHE C CE2 1 
ATOM   8208  C CZ  . PHE C 1 89  ? 116.704 119.017 116.253 1.00 22.36  ? 89  PHE C CZ  1 
ATOM   8209  N N   . VAL C 1 90  ? 117.761 118.705 121.293 1.00 24.37  ? 90  VAL C N   1 
ATOM   8210  C CA  . VAL C 1 90  ? 118.730 117.685 121.679 1.00 24.37  ? 90  VAL C CA  1 
ATOM   8211  C C   . VAL C 1 90  ? 119.210 116.984 120.417 1.00 24.37  ? 90  VAL C C   1 
ATOM   8212  O O   . VAL C 1 90  ? 118.405 116.428 119.661 1.00 24.37  ? 90  VAL C O   1 
ATOM   8213  C CB  . VAL C 1 90  ? 118.132 116.681 122.677 1.00 24.37  ? 90  VAL C CB  1 
ATOM   8214  C CG1 . VAL C 1 90  ? 119.189 115.689 123.125 1.00 24.37  ? 90  VAL C CG1 1 
ATOM   8215  C CG2 . VAL C 1 90  ? 117.548 117.411 123.872 1.00 24.37  ? 90  VAL C CG2 1 
ATOM   8216  N N   . GLU C 1 91  ? 120.521 117.007 120.195 1.00 25.62  ? 91  GLU C N   1 
ATOM   8217  C CA  . GLU C 1 91  ? 121.139 116.379 119.035 1.00 25.62  ? 91  GLU C CA  1 
ATOM   8218  C C   . GLU C 1 91  ? 121.850 115.104 119.463 1.00 25.62  ? 91  GLU C C   1 
ATOM   8219  O O   . GLU C 1 91  ? 122.647 115.119 120.406 1.00 25.62  ? 91  GLU C O   1 
ATOM   8220  C CB  . GLU C 1 91  ? 122.129 117.331 118.362 1.00 25.62  ? 91  GLU C CB  1 
ATOM   8221  C CG  . GLU C 1 91  ? 121.536 118.152 117.231 1.00 25.62  ? 91  GLU C CG  1 
ATOM   8222  C CD  . GLU C 1 91  ? 122.583 118.952 116.482 1.00 25.62  ? 91  GLU C CD  1 
ATOM   8223  O OE1 . GLU C 1 91  ? 123.765 118.907 116.879 1.00 25.62  ? 91  GLU C OE1 1 
ATOM   8224  O OE2 . GLU C 1 91  ? 122.224 119.629 115.497 1.00 25.62  ? 91  GLU C OE2 1 
ATOM   8225  N N   . ARG C 1 92  ? 121.563 114.008 118.769 1.00 27.66  ? 92  ARG C N   1 
ATOM   8226  C CA  . ARG C 1 92  ? 122.190 112.727 119.057 1.00 27.66  ? 92  ARG C CA  1 
ATOM   8227  C C   . ARG C 1 92  ? 123.405 112.516 118.163 1.00 27.66  ? 92  ARG C C   1 
ATOM   8228  O O   . ARG C 1 92  ? 123.485 113.047 117.052 1.00 27.66  ? 92  ARG C O   1 
ATOM   8229  C CB  . ARG C 1 92  ? 121.195 111.581 118.865 1.00 27.66  ? 92  ARG C CB  1 
ATOM   8230  C CG  . ARG C 1 92  ? 119.810 111.851 119.431 1.00 27.66  ? 92  ARG C CG  1 
ATOM   8231  C CD  . ARG C 1 92  ? 119.861 112.159 120.915 1.00 27.66  ? 92  ARG C CD  1 
ATOM   8232  N NE  . ARG C 1 92  ? 118.627 111.778 121.591 1.00 27.66  ? 92  ARG C NE  1 
ATOM   8233  C CZ  . ARG C 1 92  ? 118.454 111.804 122.905 1.00 27.66  ? 92  ARG C CZ  1 
ATOM   8234  N NH1 . ARG C 1 92  ? 119.416 112.200 123.721 1.00 27.66  ? 92  ARG C NH1 1 
ATOM   8235  N NH2 . ARG C 1 92  ? 117.286 111.422 123.413 1.00 27.66  ? 92  ARG C NH2 1 
ATOM   8236  N N   . SER C 1 93  ? 124.359 111.730 118.663 1.00 30.94  ? 93  SER C N   1 
ATOM   8237  C CA  . SER C 1 93  ? 125.587 111.457 117.927 1.00 30.94  ? 93  SER C CA  1 
ATOM   8238  C C   . SER C 1 93  ? 125.386 110.493 116.766 1.00 30.94  ? 93  SER C C   1 
ATOM   8239  O O   . SER C 1 93  ? 126.306 110.321 115.960 1.00 30.94  ? 93  SER C O   1 
ATOM   8240  C CB  . SER C 1 93  ? 126.655 110.903 118.873 1.00 30.94  ? 93  SER C CB  1 
ATOM   8241  O OG  . SER C 1 93  ? 126.486 109.511 119.075 1.00 30.94  ? 93  SER C OG  1 
ATOM   8242  N N   . SER C 1 94  ? 124.218 109.866 116.659 1.00 30.88  ? 94  SER C N   1 
ATOM   8243  C CA  . SER C 1 94  ? 123.916 108.945 115.574 1.00 30.88  ? 94  SER C CA  1 
ATOM   8244  C C   . SER C 1 94  ? 123.231 109.626 114.395 1.00 30.88  ? 94  SER C C   1 
ATOM   8245  O O   . SER C 1 94  ? 122.813 108.940 113.457 1.00 30.88  ? 94  SER C O   1 
ATOM   8246  C CB  . SER C 1 94  ? 123.047 107.795 116.088 1.00 30.88  ? 94  SER C CB  1 
ATOM   8247  O OG  . SER C 1 94  ? 121.873 108.284 116.712 1.00 30.88  ? 94  SER C OG  1 
ATOM   8248  N N   . ALA C 1 95  ? 123.100 110.949 114.426 1.00 29.83  ? 95  ALA C N   1 
ATOM   8249  C CA  . ALA C 1 95  ? 122.480 111.674 113.328 1.00 29.83  ? 95  ALA C CA  1 
ATOM   8250  C C   . ALA C 1 95  ? 123.342 111.598 112.072 1.00 29.83  ? 95  ALA C C   1 
ATOM   8251  O O   . ALA C 1 95  ? 124.573 111.565 112.136 1.00 29.83  ? 95  ALA C O   1 
ATOM   8252  C CB  . ALA C 1 95  ? 122.250 113.133 113.717 1.00 29.83  ? 95  ALA C CB  1 
ATOM   8253  N N   . PHE C 1 96  ? 122.678 111.573 110.918 1.00 28.56  ? 96  PHE C N   1 
ATOM   8254  C CA  . PHE C 1 96  ? 123.367 111.470 109.640 1.00 28.56  ? 96  PHE C CA  1 
ATOM   8255  C C   . PHE C 1 96  ? 122.609 112.274 108.592 1.00 28.56  ? 96  PHE C C   1 
ATOM   8256  O O   . PHE C 1 96  ? 121.482 112.722 108.815 1.00 28.56  ? 96  PHE C O   1 
ATOM   8257  C CB  . PHE C 1 96  ? 123.522 110.007 109.205 1.00 28.56  ? 96  PHE C CB  1 
ATOM   8258  C CG  . PHE C 1 96  ? 122.217 109.287 109.009 1.00 28.56  ? 96  PHE C CG  1 
ATOM   8259  C CD1 . PHE C 1 96  ? 121.603 108.641 110.068 1.00 28.56  ? 96  PHE C CD1 1 
ATOM   8260  C CD2 . PHE C 1 96  ? 121.611 109.246 107.765 1.00 28.56  ? 96  PHE C CD2 1 
ATOM   8261  C CE1 . PHE C 1 96  ? 120.406 107.976 109.890 1.00 28.56  ? 96  PHE C CE1 1 
ATOM   8262  C CE2 . PHE C 1 96  ? 120.415 108.583 107.584 1.00 28.56  ? 96  PHE C CE2 1 
ATOM   8263  C CZ  . PHE C 1 96  ? 119.813 107.948 108.647 1.00 28.56  ? 96  PHE C CZ  1 
ATOM   8264  N N   . SER C 1 97  ? 123.250 112.455 107.441 1.00 26.19  ? 97  SER C N   1 
ATOM   8265  C CA  . SER C 1 97  ? 122.679 113.168 106.308 1.00 26.19  ? 97  SER C CA  1 
ATOM   8266  C C   . SER C 1 97  ? 122.414 112.192 105.170 1.00 26.19  ? 97  SER C C   1 
ATOM   8267  O O   . SER C 1 97  ? 123.214 111.286 104.919 1.00 26.19  ? 97  SER C O   1 
ATOM   8268  C CB  . SER C 1 97  ? 123.614 114.281 105.831 1.00 26.19  ? 97  SER C CB  1 
ATOM   8269  O OG  . SER C 1 97  ? 123.703 115.321 106.788 1.00 26.19  ? 97  SER C OG  1 
ATOM   8270  N N   . ASN C 1 98  ? 121.287 112.375 104.484 1.00 26.52  ? 98  ASN C N   1 
ATOM   8271  C CA  . ASN C 1 98  ? 120.879 111.475 103.410 1.00 26.52  ? 98  ASN C CA  1 
ATOM   8272  C C   . ASN C 1 98  ? 120.317 112.260 102.230 1.00 26.52  ? 98  ASN C C   1 
ATOM   8273  O O   . ASN C 1 98  ? 119.281 111.902 101.661 1.00 26.52  ? 98  ASN C O   1 
ATOM   8274  C CB  . ASN C 1 98  ? 119.862 110.450 103.911 1.00 26.52  ? 98  ASN C CB  1 
ATOM   8275  C CG  . ASN C 1 98  ? 119.972 109.121 103.193 1.00 26.52  ? 98  ASN C CG  1 
ATOM   8276  O OD1 . ASN C 1 98  ? 121.061 108.696 102.812 1.00 26.52  ? 98  ASN C OD1 1 
ATOM   8277  N ND2 . ASN C 1 98  ? 118.840 108.455 103.010 1.00 26.52  ? 98  ASN C ND2 1 
ATOM   8278  N N   . CYS C 1 99  ? 120.990 113.338 101.845 1.00 25.07  ? 99  CYS C N   1 
ATOM   8279  C CA  . CYS C 1 99  ? 120.558 114.163 100.721 1.00 25.07  ? 99  CYS C CA  1 
ATOM   8280  C C   . CYS C 1 99  ? 121.802 114.591 99.948  1.00 25.07  ? 99  CYS C C   1 
ATOM   8281  O O   . CYS C 1 99  ? 122.881 114.006 100.092 1.00 25.07  ? 99  CYS C O   1 
ATOM   8282  C CB  . CYS C 1 99  ? 119.709 115.348 101.208 1.00 25.07  ? 99  CYS C CB  1 
ATOM   8283  S SG  . CYS C 1 99  ? 118.838 116.249 99.896  1.00 25.07  ? 99  CYS C SG  1 
ATOM   8284  N N   . TYR C 1 100 ? 121.649 115.603 99.100  1.00 22.59  ? 100 TYR C N   1 
ATOM   8285  C CA  . TYR C 1 100 ? 122.763 116.092 98.301  1.00 22.59  ? 100 TYR C CA  1 
ATOM   8286  C C   . TYR C 1 100 ? 123.875 116.615 99.209  1.00 22.59  ? 100 TYR C C   1 
ATOM   8287  O O   . TYR C 1 100 ? 123.596 117.309 100.193 1.00 22.59  ? 100 TYR C O   1 
ATOM   8288  C CB  . TYR C 1 100 ? 122.290 117.201 97.360  1.00 22.59  ? 100 TYR C CB  1 
ATOM   8289  C CG  . TYR C 1 100 ? 123.068 117.300 96.069  1.00 22.59  ? 100 TYR C CG  1 
ATOM   8290  C CD1 . TYR C 1 100 ? 124.190 118.112 95.972  1.00 22.59  ? 100 TYR C CD1 1 
ATOM   8291  C CD2 . TYR C 1 100 ? 122.677 116.589 94.945  1.00 22.59  ? 100 TYR C CD2 1 
ATOM   8292  C CE1 . TYR C 1 100 ? 124.902 118.206 94.795  1.00 22.59  ? 100 TYR C CE1 1 
ATOM   8293  C CE2 . TYR C 1 100 ? 123.382 116.678 93.764  1.00 22.59  ? 100 TYR C CE2 1 
ATOM   8294  C CZ  . TYR C 1 100 ? 124.493 117.487 93.694  1.00 22.59  ? 100 TYR C CZ  1 
ATOM   8295  O OH  . TYR C 1 100 ? 125.198 117.577 92.518  1.00 22.59  ? 100 TYR C OH  1 
ATOM   8296  N N   . PRO C 1 101 ? 125.137 116.292 98.920  1.00 21.93  ? 101 PRO C N   1 
ATOM   8297  C CA  . PRO C 1 101 ? 126.237 116.806 99.746  1.00 21.93  ? 101 PRO C CA  1 
ATOM   8298  C C   . PRO C 1 101 ? 126.309 118.325 99.701  1.00 21.93  ? 101 PRO C C   1 
ATOM   8299  O O   . PRO C 1 101 ? 126.072 118.948 98.665  1.00 21.93  ? 101 PRO C O   1 
ATOM   8300  C CB  . PRO C 1 101 ? 127.482 116.163 99.122  1.00 21.93  ? 101 PRO C CB  1 
ATOM   8301  C CG  . PRO C 1 101 ? 127.053 115.704 97.767  1.00 21.93  ? 101 PRO C CG  1 
ATOM   8302  C CD  . PRO C 1 101 ? 125.610 115.356 97.889  1.00 21.93  ? 101 PRO C CD  1 
ATOM   8303  N N   . TYR C 1 102 ? 126.650 118.919 100.842 1.00 20.40  ? 102 TYR C N   1 
ATOM   8304  C CA  . TYR C 1 102 ? 126.671 120.367 100.972 1.00 20.40  ? 102 TYR C CA  1 
ATOM   8305  C C   . TYR C 1 102 ? 127.665 120.761 102.053 1.00 20.40  ? 102 TYR C C   1 
ATOM   8306  O O   . TYR C 1 102 ? 128.105 119.936 102.856 1.00 20.40  ? 102 TYR C O   1 
ATOM   8307  C CB  . TYR C 1 102 ? 125.276 120.921 101.292 1.00 20.40  ? 102 TYR C CB  1 
ATOM   8308  C CG  . TYR C 1 102 ? 124.789 120.606 102.690 1.00 20.40  ? 102 TYR C CG  1 
ATOM   8309  C CD1 . TYR C 1 102 ? 124.145 119.409 102.967 1.00 20.40  ? 102 TYR C CD1 1 
ATOM   8310  C CD2 . TYR C 1 102 ? 124.968 121.508 103.731 1.00 20.40  ? 102 TYR C CD2 1 
ATOM   8311  C CE1 . TYR C 1 102 ? 123.700 119.117 104.240 1.00 20.40  ? 102 TYR C CE1 1 
ATOM   8312  C CE2 . TYR C 1 102 ? 124.527 121.223 105.007 1.00 20.40  ? 102 TYR C CE2 1 
ATOM   8313  C CZ  . TYR C 1 102 ? 123.892 120.026 105.255 1.00 20.40  ? 102 TYR C CZ  1 
ATOM   8314  O OH  . TYR C 1 102 ? 123.448 119.738 106.524 1.00 20.40  ? 102 TYR C OH  1 
ATOM   8315  N N   . ASP C 1 103 ? 128.021 122.043 102.059 1.00 19.79  ? 103 ASP C N   1 
ATOM   8316  C CA  . ASP C 1 103 ? 128.818 122.626 103.127 1.00 19.79  ? 103 ASP C CA  1 
ATOM   8317  C C   . ASP C 1 103 ? 128.288 124.018 103.433 1.00 19.79  ? 103 ASP C C   1 
ATOM   8318  O O   . ASP C 1 103 ? 127.760 124.704 102.555 1.00 19.79  ? 103 ASP C O   1 
ATOM   8319  C CB  . ASP C 1 103 ? 130.310 122.689 102.765 1.00 19.79  ? 103 ASP C CB  1 
ATOM   8320  C CG  . ASP C 1 103 ? 130.597 123.645 101.626 1.00 19.79  ? 103 ASP C CG  1 
ATOM   8321  O OD1 . ASP C 1 103 ? 130.374 123.263 100.458 1.00 19.79  ? 103 ASP C OD1 1 
ATOM   8322  O OD2 . ASP C 1 103 ? 131.052 124.775 101.896 1.00 19.79  ? 103 ASP C OD2 1 
ATOM   8323  N N   . VAL C 1 104 ? 128.423 124.424 104.690 1.00 19.18  ? 104 VAL C N   1 
ATOM   8324  C CA  . VAL C 1 104 ? 127.953 125.733 105.134 1.00 19.18  ? 104 VAL C CA  1 
ATOM   8325  C C   . VAL C 1 104 ? 129.144 126.551 105.619 1.00 19.18  ? 104 VAL C C   1 
ATOM   8326  O O   . VAL C 1 104 ? 129.744 126.211 106.649 1.00 19.18  ? 104 VAL C O   1 
ATOM   8327  C CB  . VAL C 1 104 ? 126.891 125.604 106.237 1.00 19.18  ? 104 VAL C CB  1 
ATOM   8328  C CG1 . VAL C 1 104 ? 126.307 126.964 106.572 1.00 19.18  ? 104 VAL C CG1 1 
ATOM   8329  C CG2 . VAL C 1 104 ? 125.797 124.640 105.816 1.00 19.18  ? 104 VAL C CG2 1 
ATOM   8330  N N   . PRO C 1 105 ? 129.534 127.611 104.916 1.00 20.97  ? 105 PRO C N   1 
ATOM   8331  C CA  . PRO C 1 105 ? 130.549 128.516 105.467 1.00 20.97  ? 105 PRO C CA  1 
ATOM   8332  C C   . PRO C 1 105 ? 130.027 129.195 106.724 1.00 20.97  ? 105 PRO C C   1 
ATOM   8333  O O   . PRO C 1 105 ? 128.924 129.748 106.738 1.00 20.97  ? 105 PRO C O   1 
ATOM   8334  C CB  . PRO C 1 105 ? 130.790 129.518 104.331 1.00 20.97  ? 105 PRO C CB  1 
ATOM   8335  C CG  . PRO C 1 105 ? 130.281 128.842 103.099 1.00 20.97  ? 105 PRO C CG  1 
ATOM   8336  C CD  . PRO C 1 105 ? 129.150 127.975 103.543 1.00 20.97  ? 105 PRO C CD  1 
ATOM   8337  N N   . ASP C 1 106 ? 130.831 129.143 107.786 1.00 21.98  ? 106 ASP C N   1 
ATOM   8338  C CA  . ASP C 1 106 ? 130.438 129.613 109.116 1.00 21.98  ? 106 ASP C CA  1 
ATOM   8339  C C   . ASP C 1 106 ? 129.207 128.846 109.609 1.00 21.98  ? 106 ASP C C   1 
ATOM   8340  O O   . ASP C 1 106 ? 128.143 129.409 109.873 1.00 21.98  ? 106 ASP C O   1 
ATOM   8341  C CB  . ASP C 1 106 ? 130.200 131.127 109.119 1.00 21.98  ? 106 ASP C CB  1 
ATOM   8342  C CG  . ASP C 1 106 ? 130.257 131.723 110.511 1.00 21.98  ? 106 ASP C CG  1 
ATOM   8343  O OD1 . ASP C 1 106 ? 130.478 130.963 111.478 1.00 21.98  ? 106 ASP C OD1 1 
ATOM   8344  O OD2 . ASP C 1 106 ? 130.085 132.953 110.637 1.00 21.98  ? 106 ASP C OD2 1 
ATOM   8345  N N   . TYR C 1 107 ? 129.384 127.527 109.720 1.00 20.52  ? 107 TYR C N   1 
ATOM   8346  C CA  . TYR C 1 107 ? 128.297 126.637 110.120 1.00 20.52  ? 107 TYR C CA  1 
ATOM   8347  C C   . TYR C 1 107 ? 127.835 126.922 111.544 1.00 20.52  ? 107 TYR C C   1 
ATOM   8348  O O   . TYR C 1 107 ? 126.633 126.875 111.840 1.00 20.52  ? 107 TYR C O   1 
ATOM   8349  C CB  . TYR C 1 107 ? 128.764 125.186 109.971 1.00 20.52  ? 107 TYR C CB  1 
ATOM   8350  C CG  . TYR C 1 107 ? 127.811 124.124 110.472 1.00 20.52  ? 107 TYR C CG  1 
ATOM   8351  C CD1 . TYR C 1 107 ? 126.858 123.567 109.632 1.00 20.52  ? 107 TYR C CD1 1 
ATOM   8352  C CD2 . TYR C 1 107 ? 127.888 123.652 111.776 1.00 20.52  ? 107 TYR C CD2 1 
ATOM   8353  C CE1 . TYR C 1 107 ? 125.996 122.588 110.081 1.00 20.52  ? 107 TYR C CE1 1 
ATOM   8354  C CE2 . TYR C 1 107 ? 127.028 122.675 112.233 1.00 20.52  ? 107 TYR C CE2 1 
ATOM   8355  C CZ  . TYR C 1 107 ? 126.085 122.146 111.382 1.00 20.52  ? 107 TYR C CZ  1 
ATOM   8356  O OH  . TYR C 1 107 ? 125.229 121.171 111.836 1.00 20.52  ? 107 TYR C OH  1 
ATOM   8357  N N   . ALA C 1 108 ? 128.779 127.221 112.441 1.00 20.75  ? 108 ALA C N   1 
ATOM   8358  C CA  . ALA C 1 108 ? 128.443 127.420 113.847 1.00 20.75  ? 108 ALA C CA  1 
ATOM   8359  C C   . ALA C 1 108 ? 127.540 128.631 114.043 1.00 20.75  ? 108 ALA C C   1 
ATOM   8360  O O   . ALA C 1 108 ? 126.625 128.600 114.872 1.00 20.75  ? 108 ALA C O   1 
ATOM   8361  C CB  . ALA C 1 108 ? 129.721 127.564 114.672 1.00 20.75  ? 108 ALA C CB  1 
ATOM   8362  N N   . SER C 1 109 ? 127.786 129.711 113.298 1.00 20.49  ? 109 SER C N   1 
ATOM   8363  C CA  . SER C 1 109 ? 126.973 130.914 113.446 1.00 20.49  ? 109 SER C CA  1 
ATOM   8364  C C   . SER C 1 109 ? 125.523 130.653 113.058 1.00 20.49  ? 109 SER C C   1 
ATOM   8365  O O   . SER C 1 109 ? 124.595 131.050 113.772 1.00 20.49  ? 109 SER C O   1 
ATOM   8366  C CB  . SER C 1 109 ? 127.559 132.048 112.607 1.00 20.49  ? 109 SER C CB  1 
ATOM   8367  O OG  . SER C 1 109 ? 128.705 132.601 113.228 1.00 20.49  ? 109 SER C OG  1 
ATOM   8368  N N   . LEU C 1 110 ? 125.307 129.978 111.926 1.00 19.08  ? 110 LEU C N   1 
ATOM   8369  C CA  . LEU C 1 110 ? 123.946 129.671 111.499 1.00 19.08  ? 110 LEU C CA  1 
ATOM   8370  C C   . LEU C 1 110 ? 123.274 128.693 112.454 1.00 19.08  ? 110 LEU C C   1 
ATOM   8371  O O   . LEU C 1 110 ? 122.082 128.833 112.757 1.00 19.08  ? 110 LEU C O   1 
ATOM   8372  C CB  . LEU C 1 110 ? 123.951 129.115 110.076 1.00 19.08  ? 110 LEU C CB  1 
ATOM   8373  C CG  . LEU C 1 110 ? 122.578 128.802 109.477 1.00 19.08  ? 110 LEU C CG  1 
ATOM   8374  C CD1 . LEU C 1 110 ? 121.705 130.046 109.447 1.00 19.08  ? 110 LEU C CD1 1 
ATOM   8375  C CD2 . LEU C 1 110 ? 122.718 128.207 108.086 1.00 19.08  ? 110 LEU C CD2 1 
ATOM   8376  N N   . ARG C 1 111 ? 124.019 127.695 112.936 1.00 20.41  ? 111 ARG C N   1 
ATOM   8377  C CA  . ARG C 1 111 ? 123.450 126.758 113.899 1.00 20.41  ? 111 ARG C CA  1 
ATOM   8378  C C   . ARG C 1 111 ? 123.012 127.477 115.169 1.00 20.41  ? 111 ARG C C   1 
ATOM   8379  O O   . ARG C 1 111 ? 121.910 127.241 115.678 1.00 20.41  ? 111 ARG C O   1 
ATOM   8380  C CB  . ARG C 1 111 ? 124.464 125.660 114.218 1.00 20.41  ? 111 ARG C CB  1 
ATOM   8381  C CG  . ARG C 1 111 ? 123.972 124.599 115.186 1.00 20.41  ? 111 ARG C CG  1 
ATOM   8382  C CD  . ARG C 1 111 ? 125.053 123.566 115.442 1.00 20.41  ? 111 ARG C CD  1 
ATOM   8383  N NE  . ARG C 1 111 ? 124.702 122.642 116.513 1.00 20.41  ? 111 ARG C NE  1 
ATOM   8384  C CZ  . ARG C 1 111 ? 125.016 122.820 117.789 1.00 20.41  ? 111 ARG C CZ  1 
ATOM   8385  N NH1 . ARG C 1 111 ? 125.674 123.893 118.194 1.00 20.41  ? 111 ARG C NH1 1 
ATOM   8386  N NH2 . ARG C 1 111 ? 124.662 121.899 118.679 1.00 20.41  ? 111 ARG C NH2 1 
ATOM   8387  N N   . SER C 1 112 ? 123.856 128.378 115.680 1.00 21.72  ? 112 SER C N   1 
ATOM   8388  C CA  . SER C 1 112 ? 123.509 129.147 116.869 1.00 21.72  ? 112 SER C CA  1 
ATOM   8389  C C   . SER C 1 112 ? 122.302 130.041 116.621 1.00 21.72  ? 112 SER C C   1 
ATOM   8390  O O   . SER C 1 112 ? 121.421 130.157 117.480 1.00 21.72  ? 112 SER C O   1 
ATOM   8391  C CB  . SER C 1 112 ? 124.709 129.982 117.314 1.00 21.72  ? 112 SER C CB  1 
ATOM   8392  O OG  . SER C 1 112 ? 124.396 130.768 118.449 1.00 21.72  ? 112 SER C OG  1 
ATOM   8393  N N   . LEU C 1 113 ? 122.247 130.684 115.453 1.00 22.07  ? 113 LEU C N   1 
ATOM   8394  C CA  . LEU C 1 113 ? 121.125 131.560 115.129 1.00 22.07  ? 113 LEU C CA  1 
ATOM   8395  C C   . LEU C 1 113 ? 119.812 130.785 115.109 1.00 22.07  ? 113 LEU C C   1 
ATOM   8396  O O   . LEU C 1 113 ? 118.819 131.203 115.719 1.00 22.07  ? 113 LEU C O   1 
ATOM   8397  C CB  . LEU C 1 113 ? 121.386 132.238 113.782 1.00 22.07  ? 113 LEU C CB  1 
ATOM   8398  C CG  . LEU C 1 113 ? 120.491 133.366 113.268 1.00 22.07  ? 113 LEU C CG  1 
ATOM   8399  C CD1 . LEU C 1 113 ? 121.301 134.269 112.361 1.00 22.07  ? 113 LEU C CD1 1 
ATOM   8400  C CD2 . LEU C 1 113 ? 119.290 132.823 112.513 1.00 22.07  ? 113 LEU C CD2 1 
ATOM   8401  N N   . ILE C 1 114 ? 119.794 129.642 114.420 1.00 21.31  ? 114 ILE C N   1 
ATOM   8402  C CA  . ILE C 1 114 ? 118.572 128.848 114.339 1.00 21.31  ? 114 ILE C CA  1 
ATOM   8403  C C   . ILE C 1 114 ? 118.185 128.310 115.711 1.00 21.31  ? 114 ILE C C   1 
ATOM   8404  O O   . ILE C 1 114 ? 117.004 128.306 116.076 1.00 21.31  ? 114 ILE C O   1 
ATOM   8405  C CB  . ILE C 1 114 ? 118.730 127.715 113.309 1.00 21.31  ? 114 ILE C CB  1 
ATOM   8406  C CG1 . ILE C 1 114 ? 119.112 128.286 111.945 1.00 21.31  ? 114 ILE C CG1 1 
ATOM   8407  C CG2 . ILE C 1 114 ? 117.442 126.919 113.193 1.00 21.31  ? 114 ILE C CG2 1 
ATOM   8408  C CD1 . ILE C 1 114 ? 118.102 129.254 111.393 1.00 21.31  ? 114 ILE C CD1 1 
ATOM   8409  N N   . ALA C 1 115 ? 119.165 127.843 116.492 1.00 21.56  ? 115 ALA C N   1 
ATOM   8410  C CA  . ALA C 1 115 ? 118.861 127.312 117.817 1.00 21.56  ? 115 ALA C CA  1 
ATOM   8411  C C   . ALA C 1 115 ? 118.283 128.385 118.729 1.00 21.56  ? 115 ALA C C   1 
ATOM   8412  O O   . ALA C 1 115 ? 117.321 128.133 119.464 1.00 21.56  ? 115 ALA C O   1 
ATOM   8413  C CB  . ALA C 1 115 ? 120.115 126.702 118.437 1.00 21.56  ? 115 ALA C CB  1 
ATOM   8414  N N   . SER C 1 116 ? 118.853 129.592 118.696 1.00 23.43  ? 116 SER C N   1 
ATOM   8415  C CA  . SER C 1 116 ? 118.366 130.662 119.556 1.00 23.43  ? 116 SER C CA  1 
ATOM   8416  C C   . SER C 1 116 ? 117.024 131.204 119.081 1.00 23.43  ? 116 SER C C   1 
ATOM   8417  O O   . SER C 1 116 ? 116.263 131.750 119.887 1.00 23.43  ? 116 SER C O   1 
ATOM   8418  C CB  . SER C 1 116 ? 119.401 131.784 119.628 1.00 23.43  ? 116 SER C CB  1 
ATOM   8419  O OG  . SER C 1 116 ? 118.954 132.837 120.461 1.00 23.43  ? 116 SER C OG  1 
ATOM   8420  N N   . SER C 1 117 ? 116.718 131.072 117.787 1.00 23.51  ? 117 SER C N   1 
ATOM   8421  C CA  . SER C 1 117 ? 115.415 131.509 117.294 1.00 23.51  ? 117 SER C CA  1 
ATOM   8422  C C   . SER C 1 117 ? 114.287 130.712 117.941 1.00 23.51  ? 117 SER C C   1 
ATOM   8423  O O   . SER C 1 117 ? 113.272 131.279 118.363 1.00 23.51  ? 117 SER C O   1 
ATOM   8424  C CB  . SER C 1 117 ? 115.362 131.386 115.772 1.00 23.51  ? 117 SER C CB  1 
ATOM   8425  O OG  . SER C 1 117 ? 114.085 131.748 115.278 1.00 23.51  ? 117 SER C OG  1 
ATOM   8426  N N   . GLY C 1 118 ? 114.445 129.394 118.027 1.00 21.40  ? 118 GLY C N   1 
ATOM   8427  C CA  . GLY C 1 118 ? 113.509 128.555 118.745 1.00 21.40  ? 118 GLY C CA  1 
ATOM   8428  C C   . GLY C 1 118 ? 112.311 128.064 117.965 1.00 21.40  ? 118 GLY C C   1 
ATOM   8429  O O   . GLY C 1 118 ? 111.393 127.500 118.571 1.00 21.40  ? 118 GLY C O   1 
ATOM   8430  N N   . THR C 1 119 ? 112.283 128.253 116.649 1.00 23.82  ? 119 THR C N   1 
ATOM   8431  C CA  . THR C 1 119 ? 111.150 127.803 115.851 1.00 23.82  ? 119 THR C CA  1 
ATOM   8432  C C   . THR C 1 119 ? 111.614 127.546 114.425 1.00 23.82  ? 119 THR C C   1 
ATOM   8433  O O   . THR C 1 119 ? 112.633 128.078 113.978 1.00 23.82  ? 119 THR C O   1 
ATOM   8434  C CB  . THR C 1 119 ? 110.005 128.823 115.874 1.00 23.82  ? 119 THR C CB  1 
ATOM   8435  O OG1 . THR C 1 119 ? 108.853 128.271 115.226 1.00 23.82  ? 119 THR C OG1 1 
ATOM   8436  C CG2 . THR C 1 119 ? 110.414 130.108 115.171 1.00 23.82  ? 119 THR C CG2 1 
ATOM   8437  N N   . LEU C 1 120 ? 110.851 126.714 113.721 1.00 24.23  ? 120 LEU C N   1 
ATOM   8438  C CA  . LEU C 1 120 ? 111.105 126.371 112.327 1.00 24.23  ? 120 LEU C CA  1 
ATOM   8439  C C   . LEU C 1 120 ? 109.896 126.695 111.458 1.00 24.23  ? 120 LEU C C   1 
ATOM   8440  O O   . LEU C 1 120 ? 109.501 125.910 110.595 1.00 24.23  ? 120 LEU C O   1 
ATOM   8441  C CB  . LEU C 1 120 ? 111.479 124.897 112.185 1.00 24.23  ? 120 LEU C CB  1 
ATOM   8442  C CG  . LEU C 1 120 ? 112.950 124.505 112.331 1.00 24.23  ? 120 LEU C CG  1 
ATOM   8443  C CD1 . LEU C 1 120 ? 113.110 123.009 112.134 1.00 24.23  ? 120 LEU C CD1 1 
ATOM   8444  C CD2 . LEU C 1 120 ? 113.822 125.272 111.355 1.00 24.23  ? 120 LEU C CD2 1 
ATOM   8445  N N   . ASP C 1 121 ? 109.296 127.863 111.674 1.00 25.76  ? 121 ASP C N   1 
ATOM   8446  C CA  . ASP C 1 121 ? 108.088 128.240 110.954 1.00 25.76  ? 121 ASP C CA  1 
ATOM   8447  C C   . ASP C 1 121 ? 108.452 128.850 109.606 1.00 25.76  ? 121 ASP C C   1 
ATOM   8448  O O   . ASP C 1 121 ? 109.239 129.798 109.535 1.00 25.76  ? 121 ASP C O   1 
ATOM   8449  C CB  . ASP C 1 121 ? 107.259 129.221 111.781 1.00 25.76  ? 121 ASP C CB  1 
ATOM   8450  C CG  . ASP C 1 121 ? 105.923 129.536 111.142 1.00 25.76  ? 121 ASP C CG  1 
ATOM   8451  O OD1 . ASP C 1 121 ? 105.026 128.669 111.184 1.00 25.76  ? 121 ASP C OD1 1 
ATOM   8452  O OD2 . ASP C 1 121 ? 105.765 130.648 110.598 1.00 25.76  ? 121 ASP C OD2 1 
ATOM   8453  N N   . PHE C 1 122 ? 107.872 128.305 108.539 1.00 21.06  ? 122 PHE C N   1 
ATOM   8454  C CA  . PHE C 1 122 ? 108.231 128.648 107.170 1.00 21.06  ? 122 PHE C CA  1 
ATOM   8455  C C   . PHE C 1 122 ? 107.002 129.159 106.432 1.00 21.06  ? 122 PHE C C   1 
ATOM   8456  O O   . PHE C 1 122 ? 105.930 128.550 106.509 1.00 21.06  ? 122 PHE C O   1 
ATOM   8457  C CB  . PHE C 1 122 ? 108.821 127.429 106.455 1.00 21.06  ? 122 PHE C CB  1 
ATOM   8458  C CG  . PHE C 1 122 ? 109.425 127.735 105.116 1.00 21.06  ? 122 PHE C CG  1 
ATOM   8459  C CD1 . PHE C 1 122 ? 110.730 128.182 105.017 1.00 21.06  ? 122 PHE C CD1 1 
ATOM   8460  C CD2 . PHE C 1 122 ? 108.695 127.554 103.955 1.00 21.06  ? 122 PHE C CD2 1 
ATOM   8461  C CE1 . PHE C 1 122 ? 111.289 128.454 103.789 1.00 21.06  ? 122 PHE C CE1 1 
ATOM   8462  C CE2 . PHE C 1 122 ? 109.250 127.827 102.724 1.00 21.06  ? 122 PHE C CE2 1 
ATOM   8463  C CZ  . PHE C 1 122 ? 110.549 128.277 102.642 1.00 21.06  ? 122 PHE C CZ  1 
ATOM   8464  N N   . ILE C 1 123 ? 107.160 130.273 105.720 1.00 22.07  ? 123 ILE C N   1 
ATOM   8465  C CA  . ILE C 1 123 ? 106.092 130.874 104.929 1.00 22.07  ? 123 ILE C CA  1 
ATOM   8466  C C   . ILE C 1 123 ? 106.513 130.864 103.467 1.00 22.07  ? 123 ILE C C   1 
ATOM   8467  O O   . ILE C 1 123 ? 107.594 131.354 103.124 1.00 22.07  ? 123 ILE C O   1 
ATOM   8468  C CB  . ILE C 1 123 ? 105.774 132.307 105.393 1.00 22.07  ? 123 ILE C CB  1 
ATOM   8469  C CG1 . ILE C 1 123 ? 105.458 132.334 106.891 1.00 22.07  ? 123 ILE C CG1 1 
ATOM   8470  C CG2 . ILE C 1 123 ? 104.625 132.889 104.583 1.00 22.07  ? 123 ILE C CG2 1 
ATOM   8471  C CD1 . ILE C 1 123 ? 104.048 131.913 107.229 1.00 22.07  ? 123 ILE C CD1 1 
ATOM   8472  N N   . THR C 1 124 ? 105.659 130.311 102.611 1.00 24.79  ? 124 THR C N   1 
ATOM   8473  C CA  . THR C 1 124 ? 105.941 130.243 101.184 1.00 24.79  ? 124 THR C CA  1 
ATOM   8474  C C   . THR C 1 124 ? 105.608 131.568 100.508 1.00 24.79  ? 124 THR C C   1 
ATOM   8475  O O   . THR C 1 124 ? 104.604 132.211 100.828 1.00 24.79  ? 124 THR C O   1 
ATOM   8476  C CB  . THR C 1 124 ? 105.144 129.109 100.537 1.00 24.79  ? 124 THR C CB  1 
ATOM   8477  O OG1 . THR C 1 124 ? 105.400 127.885 101.238 1.00 24.79  ? 124 THR C OG1 1 
ATOM   8478  C CG2 . THR C 1 124 ? 105.534 128.933 99.080  1.00 24.79  ? 124 THR C CG2 1 
ATOM   8479  N N   . GLU C 1 125 ? 106.458 131.973 99.569  1.00 23.42  ? 125 GLU C N   1 
ATOM   8480  C CA  . GLU C 1 125 ? 106.288 133.212 98.828  1.00 23.42  ? 125 GLU C CA  1 
ATOM   8481  C C   . GLU C 1 125 ? 106.268 132.923 97.333  1.00 23.42  ? 125 GLU C C   1 
ATOM   8482  O O   . GLU C 1 125 ? 106.783 131.903 96.868  1.00 23.42  ? 125 GLU C O   1 
ATOM   8483  C CB  . GLU C 1 125 ? 107.402 134.212 99.154  1.00 23.42  ? 125 GLU C CB  1 
ATOM   8484  C CG  . GLU C 1 125 ? 107.292 134.819 100.537 1.00 23.42  ? 125 GLU C CG  1 
ATOM   8485  C CD  . GLU C 1 125 ? 108.411 135.789 100.834 1.00 23.42  ? 125 GLU C CD  1 
ATOM   8486  O OE1 . GLU C 1 125 ? 109.557 135.520 100.420 1.00 23.42  ? 125 GLU C OE1 1 
ATOM   8487  O OE2 . GLU C 1 125 ? 108.145 136.822 101.482 1.00 23.42  ? 125 GLU C OE2 1 
ATOM   8488  N N   . SER C 1 126 ? 105.663 133.840 96.581  1.00 23.83  ? 126 SER C N   1 
ATOM   8489  C CA  . SER C 1 126 ? 105.472 133.668 95.141  1.00 23.83  ? 126 SER C CA  1 
ATOM   8490  C C   . SER C 1 126 ? 106.673 134.249 94.407  1.00 23.83  ? 126 SER C C   1 
ATOM   8491  O O   . SER C 1 126 ? 106.701 135.426 94.048  1.00 23.83  ? 126 SER C O   1 
ATOM   8492  C CB  . SER C 1 126 ? 104.171 134.321 94.691  1.00 23.83  ? 126 SER C CB  1 
ATOM   8493  N N   . PHE C 1 127 ? 107.680 133.411 94.184  1.00 23.86  ? 127 PHE C N   1 
ATOM   8494  C CA  . PHE C 1 127 ? 108.828 133.776 93.369  1.00 23.86  ? 127 PHE C CA  1 
ATOM   8495  C C   . PHE C 1 127 ? 108.585 133.362 91.924  1.00 23.86  ? 127 PHE C C   1 
ATOM   8496  O O   . PHE C 1 127 ? 108.120 132.252 91.655  1.00 23.86  ? 127 PHE C O   1 
ATOM   8497  C CB  . PHE C 1 127 ? 110.104 133.113 93.889  1.00 23.86  ? 127 PHE C CB  1 
ATOM   8498  C CG  . PHE C 1 127 ? 110.678 133.767 95.112  1.00 23.86  ? 127 PHE C CG  1 
ATOM   8499  C CD1 . PHE C 1 127 ? 111.460 134.904 95.002  1.00 23.86  ? 127 PHE C CD1 1 
ATOM   8500  C CD2 . PHE C 1 127 ? 110.451 133.236 96.369  1.00 23.86  ? 127 PHE C CD2 1 
ATOM   8501  C CE1 . PHE C 1 127 ? 111.995 135.503 96.123  1.00 23.86  ? 127 PHE C CE1 1 
ATOM   8502  C CE2 . PHE C 1 127 ? 110.984 133.832 97.494  1.00 23.86  ? 127 PHE C CE2 1 
ATOM   8503  C CZ  . PHE C 1 127 ? 111.757 134.966 97.371  1.00 23.86  ? 127 PHE C CZ  1 
ATOM   8504  N N   . THR C 1 128 ? 108.902 134.261 90.997  1.00 27.08  ? 128 THR C N   1 
ATOM   8505  C CA  . THR C 1 128 ? 108.746 134.009 89.570  1.00 27.08  ? 128 THR C CA  1 
ATOM   8506  C C   . THR C 1 128 ? 110.125 133.933 88.930  1.00 27.08  ? 128 THR C C   1 
ATOM   8507  O O   . THR C 1 128 ? 110.908 134.884 89.020  1.00 27.08  ? 128 THR C O   1 
ATOM   8508  C CB  . THR C 1 128 ? 107.905 135.099 88.906  1.00 27.08  ? 128 THR C CB  1 
ATOM   8509  O OG1 . THR C 1 128 ? 106.604 135.134 89.505  1.00 27.08  ? 128 THR C OG1 1 
ATOM   8510  C CG2 . THR C 1 128 ? 107.762 134.827 87.418  1.00 27.08  ? 128 THR C CG2 1 
ATOM   8511  N N   . TRP C 1 129 ? 110.416 132.806 88.286  1.00 25.41  ? 129 TRP C N   1 
ATOM   8512  C CA  . TRP C 1 129 ? 111.685 132.582 87.597  1.00 25.41  ? 129 TRP C CA  1 
ATOM   8513  C C   . TRP C 1 129 ? 111.367 132.310 86.130  1.00 25.41  ? 129 TRP C C   1 
ATOM   8514  O O   . TRP C 1 129 ? 111.006 131.188 85.763  1.00 25.41  ? 129 TRP C O   1 
ATOM   8515  C CB  . TRP C 1 129 ? 112.456 131.426 88.227  1.00 25.41  ? 129 TRP C CB  1 
ATOM   8516  C CG  . TRP C 1 129 ? 112.500 131.476 89.724  1.00 25.41  ? 129 TRP C CG  1 
ATOM   8517  C CD1 . TRP C 1 129 ? 111.748 130.739 90.589  1.00 25.41  ? 129 TRP C CD1 1 
ATOM   8518  C CD2 . TRP C 1 129 ? 113.342 132.306 90.532  1.00 25.41  ? 129 TRP C CD2 1 
ATOM   8519  N NE1 . TRP C 1 129 ? 112.068 131.057 91.885  1.00 25.41  ? 129 TRP C NE1 1 
ATOM   8520  C CE2 . TRP C 1 129 ? 113.044 132.018 91.877  1.00 25.41  ? 129 TRP C CE2 1 
ATOM   8521  C CE3 . TRP C 1 129 ? 114.319 133.264 90.248  1.00 25.41  ? 129 TRP C CE3 1 
ATOM   8522  C CZ2 . TRP C 1 129 ? 113.686 132.654 92.935  1.00 25.41  ? 129 TRP C CZ2 1 
ATOM   8523  C CZ3 . TRP C 1 129 ? 114.954 133.894 91.301  1.00 25.41  ? 129 TRP C CZ3 1 
ATOM   8524  C CH2 . TRP C 1 129 ? 114.636 133.586 92.627  1.00 25.41  ? 129 TRP C CH2 1 
ATOM   8525  N N   . ALA C 1 130 ? 111.503 133.335 85.294  1.00 28.91  ? 130 ALA C N   1 
ATOM   8526  C CA  . ALA C 1 130 ? 111.112 133.250 83.894  1.00 28.91  ? 130 ALA C CA  1 
ATOM   8527  C C   . ALA C 1 130 ? 112.274 132.762 83.040  1.00 28.91  ? 130 ALA C C   1 
ATOM   8528  O O   . ALA C 1 130 ? 113.364 133.342 83.071  1.00 28.91  ? 130 ALA C O   1 
ATOM   8529  C CB  . ALA C 1 130 ? 110.623 134.609 83.393  1.00 28.91  ? 130 ALA C CB  1 
ATOM   8530  N N   . GLY C 1 131 ? 112.035 131.698 82.279  1.00 30.04  ? 131 GLY C N   1 
ATOM   8531  C CA  . GLY C 1 131 ? 112.998 131.202 81.320  1.00 30.04  ? 131 GLY C CA  1 
ATOM   8532  C C   . GLY C 1 131 ? 113.887 130.072 81.788  1.00 30.04  ? 131 GLY C C   1 
ATOM   8533  O O   . GLY C 1 131 ? 114.819 129.708 81.063  1.00 30.04  ? 131 GLY C O   1 
ATOM   8534  N N   . VAL C 1 132 ? 113.634 129.503 82.967  1.00 28.01  ? 132 VAL C N   1 
ATOM   8535  C CA  . VAL C 1 132 ? 114.459 128.432 83.506  1.00 28.01  ? 132 VAL C CA  1 
ATOM   8536  C C   . VAL C 1 132 ? 113.559 127.308 83.999  1.00 28.01  ? 132 VAL C C   1 
ATOM   8537  O O   . VAL C 1 132 ? 112.368 127.497 84.256  1.00 28.01  ? 132 VAL C O   1 
ATOM   8538  C CB  . VAL C 1 132 ? 115.380 128.918 84.647  1.00 28.01  ? 132 VAL C CB  1 
ATOM   8539  C CG1 . VAL C 1 132 ? 116.419 129.892 84.118  1.00 28.01  ? 132 VAL C CG1 1 
ATOM   8540  C CG2 . VAL C 1 132 ? 114.562 129.549 85.760  1.00 28.01  ? 132 VAL C CG2 1 
ATOM   8541  N N   . SER C 1 133 ? 114.149 126.124 84.122  1.00 28.32  ? 133 SER C N   1 
ATOM   8542  C CA  . SER C 1 133 ? 113.470 124.965 84.678  1.00 28.32  ? 133 SER C CA  1 
ATOM   8543  C C   . SER C 1 133 ? 113.523 125.003 86.201  1.00 28.32  ? 133 SER C C   1 
ATOM   8544  O O   . SER C 1 133 ? 114.403 125.622 86.801  1.00 28.32  ? 133 SER C O   1 
ATOM   8545  C CB  . SER C 1 133 ? 114.097 123.671 84.161  1.00 28.32  ? 133 SER C CB  1 
ATOM   8546  O OG  . SER C 1 133 ? 113.743 123.436 82.810  1.00 28.32  ? 133 SER C OG  1 
ATOM   8547  N N   . GLN C 1 134 ? 112.561 124.329 86.826  1.00 27.49  ? 134 GLN C N   1 
ATOM   8548  C CA  . GLN C 1 134 ? 112.421 124.333 88.273  1.00 27.49  ? 134 GLN C CA  1 
ATOM   8549  C C   . GLN C 1 134 ? 112.321 122.905 88.791  1.00 27.49  ? 134 GLN C C   1 
ATOM   8550  O O   . GLN C 1 134 ? 112.164 121.949 88.028  1.00 27.49  ? 134 GLN C O   1 
ATOM   8551  C CB  . GLN C 1 134 ? 111.190 125.138 88.713  1.00 27.49  ? 134 GLN C CB  1 
ATOM   8552  C CG  . GLN C 1 134 ? 111.136 126.550 88.165  1.00 27.49  ? 134 GLN C CG  1 
ATOM   8553  C CD  . GLN C 1 134 ? 110.091 127.397 88.856  1.00 27.49  ? 134 GLN C CD  1 
ATOM   8554  O OE1 . GLN C 1 134 ? 109.565 127.019 89.902  1.00 27.49  ? 134 GLN C OE1 1 
ATOM   8555  N NE2 . GLN C 1 134 ? 109.784 128.549 88.276  1.00 27.49  ? 134 GLN C NE2 1 
ATOM   8556  N N   . ASN C 1 135 ? 112.424 122.779 90.116  1.00 26.80  ? 135 ASN C N   1 
ATOM   8557  C CA  . ASN C 1 135 ? 112.230 121.512 90.823  1.00 26.80  ? 135 ASN C CA  1 
ATOM   8558  C C   . ASN C 1 135 ? 113.219 120.445 90.353  1.00 26.80  ? 135 ASN C C   1 
ATOM   8559  O O   . ASN C 1 135 ? 112.839 119.346 89.946  1.00 26.80  ? 135 ASN C O   1 
ATOM   8560  C CB  . ASN C 1 135 ? 110.786 121.022 90.679  1.00 26.80  ? 135 ASN C CB  1 
ATOM   8561  C CG  . ASN C 1 135 ? 109.771 122.087 91.040  1.00 26.80  ? 135 ASN C CG  1 
ATOM   8562  O OD1 . ASN C 1 135 ? 109.843 122.692 92.108  1.00 26.80  ? 135 ASN C OD1 1 
ATOM   8563  N ND2 . ASN C 1 135 ? 108.815 122.318 90.150  1.00 26.80  ? 135 ASN C ND2 1 
ATOM   8564  N N   . GLY C 1 136 ? 114.506 120.780 90.415  1.00 27.04  ? 136 GLY C N   1 
ATOM   8565  C CA  . GLY C 1 136 ? 115.535 119.814 90.084  1.00 27.04  ? 136 GLY C CA  1 
ATOM   8566  C C   . GLY C 1 136 ? 115.779 118.830 91.214  1.00 27.04  ? 136 GLY C C   1 
ATOM   8567  O O   . GLY C 1 136 ? 115.602 119.137 92.391  1.00 27.04  ? 136 GLY C O   1 
ATOM   8568  N N   . GLY C 1 137 ? 116.203 117.620 90.839  1.00 29.24  ? 137 GLY C N   1 
ATOM   8569  C CA  . GLY C 1 137 ? 116.418 116.566 91.806  1.00 29.24  ? 137 GLY C CA  1 
ATOM   8570  C C   . GLY C 1 137 ? 117.626 115.724 91.449  1.00 29.24  ? 137 GLY C C   1 
ATOM   8571  O O   . GLY C 1 137 ? 118.196 115.844 90.364  1.00 29.24  ? 137 GLY C O   1 
ATOM   8572  N N   . SER C 1 138 ? 118.006 114.864 92.391  1.00 29.69  ? 138 SER C N   1 
ATOM   8573  C CA  . SER C 1 138 ? 119.157 113.994 92.215  1.00 29.69  ? 138 SER C CA  1 
ATOM   8574  C C   . SER C 1 138 ? 118.872 112.650 92.868  1.00 29.69  ? 138 SER C C   1 
ATOM   8575  O O   . SER C 1 138 ? 118.027 112.538 93.759  1.00 29.69  ? 138 SER C O   1 
ATOM   8576  C CB  . SER C 1 138 ? 120.427 114.616 92.806  1.00 29.69  ? 138 SER C CB  1 
ATOM   8577  O OG  . SER C 1 138 ? 121.565 113.824 92.518  1.00 29.69  ? 138 SER C OG  1 
ATOM   8578  N N   . SER C 1 139 ? 119.592 111.625 92.410  1.00 29.24  ? 139 SER C N   1 
ATOM   8579  C CA  . SER C 1 139 ? 119.461 110.297 92.997  1.00 29.24  ? 139 SER C CA  1 
ATOM   8580  C C   . SER C 1 139 ? 120.102 110.198 94.373  1.00 29.24  ? 139 SER C C   1 
ATOM   8581  O O   . SER C 1 139 ? 119.873 109.207 95.074  1.00 29.24  ? 139 SER C O   1 
ATOM   8582  C CB  . SER C 1 139 ? 120.073 109.247 92.068  1.00 29.24  ? 139 SER C CB  1 
ATOM   8583  O OG  . SER C 1 139 ? 121.485 109.350 92.043  1.00 29.24  ? 139 SER C OG  1 
ATOM   8584  N N   . ALA C 1 140 ? 120.896 111.190 94.773  1.00 28.58  ? 140 ALA C N   1 
ATOM   8585  C CA  . ALA C 1 140 ? 121.488 111.214 96.103  1.00 28.58  ? 140 ALA C CA  1 
ATOM   8586  C C   . ALA C 1 140 ? 120.512 111.675 97.174  1.00 28.58  ? 140 ALA C C   1 
ATOM   8587  O O   . ALA C 1 140 ? 120.850 111.620 98.361  1.00 28.58  ? 140 ALA C O   1 
ATOM   8588  C CB  . ALA C 1 140 ? 122.723 112.118 96.113  1.00 28.58  ? 140 ALA C CB  1 
ATOM   8589  N N   . CYS C 1 141 ? 119.319 112.123 96.788  1.00 30.44  ? 141 CYS C N   1 
ATOM   8590  C CA  . CYS C 1 141 ? 118.311 112.639 97.713  1.00 30.44  ? 141 CYS C CA  1 
ATOM   8591  C C   . CYS C 1 141 ? 116.966 112.103 97.229  1.00 30.44  ? 141 CYS C C   1 
ATOM   8592  O O   . CYS C 1 141 ? 116.333 112.695 96.352  1.00 30.44  ? 141 CYS C O   1 
ATOM   8593  C CB  . CYS C 1 141 ? 118.350 114.165 97.752  1.00 30.44  ? 141 CYS C CB  1 
ATOM   8594  S SG  . CYS C 1 141 ? 117.495 114.922 99.143  1.00 30.44  ? 141 CYS C SG  1 
ATOM   8595  N N   . LYS C 1 142 ? 116.535 110.979 97.795  1.00 34.03  ? 142 LYS C N   1 
ATOM   8596  C CA  . LYS C 1 142 ? 115.369 110.250 97.312  1.00 34.03  ? 142 LYS C CA  1 
ATOM   8597  C C   . LYS C 1 142 ? 114.139 110.577 98.149  1.00 34.03  ? 142 LYS C C   1 
ATOM   8598  O O   . LYS C 1 142 ? 114.183 110.508 99.381  1.00 34.03  ? 142 LYS C O   1 
ATOM   8599  C CB  . LYS C 1 142 ? 115.624 108.742 97.341  1.00 34.03  ? 142 LYS C CB  1 
ATOM   8600  C CG  . LYS C 1 142 ? 116.886 108.301 96.624  1.00 34.03  ? 142 LYS C CG  1 
ATOM   8601  C CD  . LYS C 1 142 ? 116.719 108.365 95.118  1.00 34.03  ? 142 LYS C CD  1 
ATOM   8602  C CE  . LYS C 1 142 ? 115.970 107.154 94.596  1.00 34.03  ? 142 LYS C CE  1 
ATOM   8603  N NZ  . LYS C 1 142 ? 115.974 107.105 93.109  1.00 34.03  ? 142 LYS C NZ  1 
ATOM   8604  N N   . ARG C 1 143 ? 113.045 110.927 97.474  1.00 34.13  ? 143 ARG C N   1 
ATOM   8605  C CA  . ARG C 1 143 ? 111.722 111.033 98.091  1.00 34.13  ? 143 ARG C CA  1 
ATOM   8606  C C   . ARG C 1 143 ? 110.943 109.782 97.701  1.00 34.13  ? 143 ARG C C   1 
ATOM   8607  O O   . ARG C 1 143 ? 110.186 109.775 96.731  1.00 34.13  ? 143 ARG C O   1 
ATOM   8608  C CB  . ARG C 1 143 ? 111.000 112.302 97.652  1.00 34.13  ? 143 ARG C CB  1 
ATOM   8609  C CG  . ARG C 1 143 ? 111.699 113.595 98.018  1.00 34.13  ? 143 ARG C CG  1 
ATOM   8610  C CD  . ARG C 1 143 ? 111.670 113.792 99.522  1.00 34.13  ? 143 ARG C CD  1 
ATOM   8611  N NE  . ARG C 1 143 ? 112.338 115.018 99.940  1.00 34.13  ? 143 ARG C NE  1 
ATOM   8612  C CZ  . ARG C 1 143 ? 111.736 116.191 100.069 1.00 34.13  ? 143 ARG C CZ  1 
ATOM   8613  N NH1 . ARG C 1 143 ? 110.445 116.335 99.824  1.00 34.13  ? 143 ARG C NH1 1 
ATOM   8614  N NH2 . ARG C 1 143 ? 112.446 117.244 100.461 1.00 34.13  ? 143 ARG C NH2 1 
ATOM   8615  N N   . GLY C 1 144 ? 111.131 108.716 98.472  1.00 37.36  ? 144 GLY C N   1 
ATOM   8616  C CA  . GLY C 1 144 ? 110.530 107.443 98.159  1.00 37.36  ? 144 GLY C CA  1 
ATOM   8617  C C   . GLY C 1 144 ? 111.262 106.744 97.033  1.00 37.36  ? 144 GLY C C   1 
ATOM   8618  O O   . GLY C 1 144 ? 112.455 106.438 97.131  1.00 37.36  ? 144 GLY C O   1 
ATOM   8619  N N   . PRO C 1 145 ? 110.555 106.470 95.934  1.00 38.85  ? 145 PRO C N   1 
ATOM   8620  C CA  . PRO C 1 145 ? 111.194 105.837 94.775  1.00 38.85  ? 145 PRO C CA  1 
ATOM   8621  C C   . PRO C 1 145 ? 111.753 106.802 93.742  1.00 38.85  ? 145 PRO C C   1 
ATOM   8622  O O   . PRO C 1 145 ? 112.511 106.362 92.866  1.00 38.85  ? 145 PRO C O   1 
ATOM   8623  C CB  . PRO C 1 145 ? 110.049 105.005 94.171  1.00 38.85  ? 145 PRO C CB  1 
ATOM   8624  C CG  . PRO C 1 145 ? 108.777 105.668 94.645  1.00 38.85  ? 145 PRO C CG  1 
ATOM   8625  C CD  . PRO C 1 145 ? 109.107 106.647 95.742  1.00 38.85  ? 145 PRO C CD  1 
ATOM   8626  N N   . ALA C 1 146 ? 111.412 108.085 93.811  1.00 36.14  ? 146 ALA C N   1 
ATOM   8627  C CA  . ALA C 1 146 ? 111.809 109.064 92.811  1.00 36.14  ? 146 ALA C CA  1 
ATOM   8628  C C   . ALA C 1 146 ? 112.870 110.006 93.368  1.00 36.14  ? 146 ALA C C   1 
ATOM   8629  O O   . ALA C 1 146 ? 113.072 110.115 94.580  1.00 36.14  ? 146 ALA C O   1 
ATOM   8630  C CB  . ALA C 1 146 ? 110.594 109.860 92.323  1.00 36.14  ? 146 ALA C CB  1 
ATOM   8631  N N   . ASN C 1 147 ? 113.552 110.689 92.452  1.00 33.36  ? 147 ASN C N   1 
ATOM   8632  C CA  . ASN C 1 147 ? 114.578 111.653 92.820  1.00 33.36  ? 147 ASN C CA  1 
ATOM   8633  C C   . ASN C 1 147 ? 113.951 112.868 93.489  1.00 33.36  ? 147 ASN C C   1 
ATOM   8634  O O   . ASN C 1 147 ? 112.811 113.238 93.197  1.00 33.36  ? 147 ASN C O   1 
ATOM   8635  C CB  . ASN C 1 147 ? 115.368 112.089 91.586  1.00 33.36  ? 147 ASN C CB  1 
ATOM   8636  C CG  . ASN C 1 147 ? 116.173 110.959 90.981  1.00 33.36  ? 147 ASN C CG  1 
ATOM   8637  O OD1 . ASN C 1 147 ? 116.339 109.904 91.590  1.00 33.36  ? 147 ASN C OD1 1 
ATOM   8638  N ND2 . ASN C 1 147 ? 116.679 111.176 89.773  1.00 33.36  ? 147 ASN C ND2 1 
ATOM   8639  N N   . GLY C 1 148 ? 114.705 113.491 94.390  1.00 27.69  ? 148 GLY C N   1 
ATOM   8640  C CA  . GLY C 1 148 ? 114.211 114.655 95.096  1.00 27.69  ? 148 GLY C CA  1 
ATOM   8641  C C   . GLY C 1 148 ? 115.290 115.657 95.446  1.00 27.69  ? 148 GLY C C   1 
ATOM   8642  O O   . GLY C 1 148 ? 116.403 115.597 94.918  1.00 27.69  ? 148 GLY C O   1 
ATOM   8643  N N   . PHE C 1 149 ? 114.966 116.583 96.340  1.00 22.97  ? 149 PHE C N   1 
ATOM   8644  C CA  . PHE C 1 149 ? 115.885 117.632 96.758  1.00 22.97  ? 149 PHE C CA  1 
ATOM   8645  C C   . PHE C 1 149 ? 115.406 118.155 98.106  1.00 22.97  ? 149 PHE C C   1 
ATOM   8646  O O   . PHE C 1 149 ? 114.407 117.683 98.655  1.00 22.97  ? 149 PHE C O   1 
ATOM   8647  C CB  . PHE C 1 149 ? 115.963 118.742 95.705  1.00 22.97  ? 149 PHE C CB  1 
ATOM   8648  C CG  . PHE C 1 149 ? 117.211 119.575 95.783  1.00 22.97  ? 149 PHE C CG  1 
ATOM   8649  C CD1 . PHE C 1 149 ? 118.459 118.995 95.647  1.00 22.97  ? 149 PHE C CD1 1 
ATOM   8650  C CD2 . PHE C 1 149 ? 117.133 120.943 95.982  1.00 22.97  ? 149 PHE C CD2 1 
ATOM   8651  C CE1 . PHE C 1 149 ? 119.605 119.761 95.715  1.00 22.97  ? 149 PHE C CE1 1 
ATOM   8652  C CE2 . PHE C 1 149 ? 118.274 121.714 96.050  1.00 22.97  ? 149 PHE C CE2 1 
ATOM   8653  C CZ  . PHE C 1 149 ? 119.512 121.122 95.917  1.00 22.97  ? 149 PHE C CZ  1 
ATOM   8654  N N   . PHE C 1 150 ? 116.136 119.128 98.647  1.00 22.05  ? 150 PHE C N   1 
ATOM   8655  C CA  . PHE C 1 150 ? 115.692 119.797 99.861  1.00 22.05  ? 150 PHE C CA  1 
ATOM   8656  C C   . PHE C 1 150 ? 114.340 120.458 99.626  1.00 22.05  ? 150 PHE C C   1 
ATOM   8657  O O   . PHE C 1 150 ? 114.098 121.058 98.575  1.00 22.05  ? 150 PHE C O   1 
ATOM   8658  C CB  . PHE C 1 150 ? 116.721 120.836 100.305 1.00 22.05  ? 150 PHE C CB  1 
ATOM   8659  C CG  . PHE C 1 150 ? 118.078 120.262 100.593 1.00 22.05  ? 150 PHE C CG  1 
ATOM   8660  C CD1 . PHE C 1 150 ? 118.333 119.619 101.792 1.00 22.05  ? 150 PHE C CD1 1 
ATOM   8661  C CD2 . PHE C 1 150 ? 119.103 120.374 99.669  1.00 22.05  ? 150 PHE C CD2 1 
ATOM   8662  C CE1 . PHE C 1 150 ? 119.581 119.093 102.061 1.00 22.05  ? 150 PHE C CE1 1 
ATOM   8663  C CE2 . PHE C 1 150 ? 120.353 119.851 99.933  1.00 22.05  ? 150 PHE C CE2 1 
ATOM   8664  C CZ  . PHE C 1 150 ? 120.592 119.210 101.130 1.00 22.05  ? 150 PHE C CZ  1 
ATOM   8665  N N   . SER C 1 151 ? 113.449 120.339 100.610 1.00 23.65  ? 151 SER C N   1 
ATOM   8666  C CA  . SER C 1 151 ? 112.085 120.825 100.444 1.00 23.65  ? 151 SER C CA  1 
ATOM   8667  C C   . SER C 1 151 ? 111.973 122.339 100.553 1.00 23.65  ? 151 SER C C   1 
ATOM   8668  O O   . SER C 1 151 ? 110.966 122.902 100.112 1.00 23.65  ? 151 SER C O   1 
ATOM   8669  C CB  . SER C 1 151 ? 111.163 120.165 101.471 1.00 23.65  ? 151 SER C CB  1 
ATOM   8670  O OG  . SER C 1 151 ? 111.348 120.720 102.759 1.00 23.65  ? 151 SER C OG  1 
ATOM   8671  N N   . ARG C 1 152 ? 112.970 123.010 101.125 1.00 22.21  ? 152 ARG C N   1 
ATOM   8672  C CA  . ARG C 1 152 ? 112.950 124.458 101.269 1.00 22.21  ? 152 ARG C CA  1 
ATOM   8673  C C   . ARG C 1 152 ? 113.795 125.175 100.225 1.00 22.21  ? 152 ARG C C   1 
ATOM   8674  O O   . ARG C 1 152 ? 113.936 126.398 100.299 1.00 22.21  ? 152 ARG C O   1 
ATOM   8675  C CB  . ARG C 1 152 ? 113.421 124.858 102.671 1.00 22.21  ? 152 ARG C CB  1 
ATOM   8676  C CG  . ARG C 1 152 ? 112.641 124.211 103.799 1.00 22.21  ? 152 ARG C CG  1 
ATOM   8677  C CD  . ARG C 1 152 ? 111.150 124.390 103.608 1.00 22.21  ? 152 ARG C CD  1 
ATOM   8678  N NE  . ARG C 1 152 ? 110.401 124.100 104.823 1.00 22.21  ? 152 ARG C NE  1 
ATOM   8679  C CZ  . ARG C 1 152 ? 109.091 123.903 104.864 1.00 22.21  ? 152 ARG C CZ  1 
ATOM   8680  N NH1 . ARG C 1 152 ? 108.352 123.942 103.768 1.00 22.21  ? 152 ARG C NH1 1 
ATOM   8681  N NH2 . ARG C 1 152 ? 108.507 123.663 106.034 1.00 22.21  ? 152 ARG C NH2 1 
ATOM   8682  N N   . LEU C 1 153 ? 114.351 124.451 99.256  1.00 20.90  ? 153 LEU C N   1 
ATOM   8683  C CA  . LEU C 1 153 ? 115.214 125.032 98.240  1.00 20.90  ? 153 LEU C CA  1 
ATOM   8684  C C   . LEU C 1 153 ? 114.731 124.620 96.858  1.00 20.90  ? 153 LEU C C   1 
ATOM   8685  O O   . LEU C 1 153 ? 114.089 123.581 96.691  1.00 20.90  ? 153 LEU C O   1 
ATOM   8686  C CB  . LEU C 1 153 ? 116.673 124.603 98.432  1.00 20.90  ? 153 LEU C CB  1 
ATOM   8687  C CG  . LEU C 1 153 ? 117.338 125.027 99.743  1.00 20.90  ? 153 LEU C CG  1 
ATOM   8688  C CD1 . LEU C 1 153 ? 118.550 124.160 100.031 1.00 20.90  ? 153 LEU C CD1 1 
ATOM   8689  C CD2 . LEU C 1 153 ? 117.725 126.494 99.697  1.00 20.90  ? 153 LEU C CD2 1 
ATOM   8690  N N   . ASN C 1 154 ? 115.048 125.449 95.865  1.00 22.98  ? 154 ASN C N   1 
ATOM   8691  C CA  . ASN C 1 154 ? 114.625 125.232 94.486  1.00 22.98  ? 154 ASN C CA  1 
ATOM   8692  C C   . ASN C 1 154 ? 115.854 125.208 93.591  1.00 22.98  ? 154 ASN C C   1 
ATOM   8693  O O   . ASN C 1 154 ? 116.632 126.167 93.577  1.00 22.98  ? 154 ASN C O   1 
ATOM   8694  C CB  . ASN C 1 154 ? 113.649 126.323 94.037  1.00 22.98  ? 154 ASN C CB  1 
ATOM   8695  C CG  . ASN C 1 154 ? 112.851 125.927 92.813  1.00 22.98  ? 154 ASN C CG  1 
ATOM   8696  O OD1 . ASN C 1 154 ? 113.082 124.877 92.219  1.00 22.98  ? 154 ASN C OD1 1 
ATOM   8697  N ND2 . ASN C 1 154 ? 111.899 126.767 92.433  1.00 22.98  ? 154 ASN C ND2 1 
ATOM   8698  N N   . TRP C 1 155 ? 116.026 124.120 92.845  1.00 24.63  ? 155 TRP C N   1 
ATOM   8699  C CA  . TRP C 1 155 ? 117.160 123.961 91.940  1.00 24.63  ? 155 TRP C CA  1 
ATOM   8700  C C   . TRP C 1 155 ? 116.727 124.381 90.540  1.00 24.63  ? 155 TRP C C   1 
ATOM   8701  O O   . TRP C 1 155 ? 115.892 123.719 89.916  1.00 24.63  ? 155 TRP C O   1 
ATOM   8702  C CB  . TRP C 1 155 ? 117.659 122.518 91.958  1.00 24.63  ? 155 TRP C CB  1 
ATOM   8703  C CG  . TRP C 1 155 ? 119.001 122.313 91.314  1.00 24.63  ? 155 TRP C CG  1 
ATOM   8704  C CD1 . TRP C 1 155 ? 119.694 123.207 90.552  1.00 24.63  ? 155 TRP C CD1 1 
ATOM   8705  C CD2 . TRP C 1 155 ? 119.808 121.131 91.377  1.00 24.63  ? 155 TRP C CD2 1 
ATOM   8706  N NE1 . TRP C 1 155 ? 120.881 122.656 90.137  1.00 24.63  ? 155 TRP C NE1 1 
ATOM   8707  C CE2 . TRP C 1 155 ? 120.975 121.382 90.631  1.00 24.63  ? 155 TRP C CE2 1 
ATOM   8708  C CE3 . TRP C 1 155 ? 119.657 119.886 91.993  1.00 24.63  ? 155 TRP C CE3 1 
ATOM   8709  C CZ2 . TRP C 1 155 ? 121.985 120.435 90.485  1.00 24.63  ? 155 TRP C CZ2 1 
ATOM   8710  C CZ3 . TRP C 1 155 ? 120.660 118.947 91.847  1.00 24.63  ? 155 TRP C CZ3 1 
ATOM   8711  C CH2 . TRP C 1 155 ? 121.809 119.227 91.099  1.00 24.63  ? 155 TRP C CH2 1 
ATOM   8712  N N   . LEU C 1 156 ? 117.300 125.474 90.045  1.00 24.77  ? 156 LEU C N   1 
ATOM   8713  C CA  . LEU C 1 156 ? 116.962 126.018 88.737  1.00 24.77  ? 156 LEU C CA  1 
ATOM   8714  C C   . LEU C 1 156 ? 118.072 125.705 87.744  1.00 24.77  ? 156 LEU C C   1 
ATOM   8715  O O   . LEU C 1 156 ? 119.251 125.935 88.029  1.00 24.77  ? 156 LEU C O   1 
ATOM   8716  C CB  . LEU C 1 156 ? 116.743 127.530 88.815  1.00 24.77  ? 156 LEU C CB  1 
ATOM   8717  C CG  . LEU C 1 156 ? 115.871 128.068 89.948  1.00 24.77  ? 156 LEU C CG  1 
ATOM   8718  C CD1 . LEU C 1 156 ? 116.084 129.560 90.100  1.00 24.77  ? 156 LEU C CD1 1 
ATOM   8719  C CD2 . LEU C 1 156 ? 114.409 127.758 89.693  1.00 24.77  ? 156 LEU C CD2 1 
ATOM   8720  N N   . THR C 1 157 ? 117.691 125.181 86.581  1.00 27.09  ? 157 THR C N   1 
ATOM   8721  C CA  . THR C 1 157 ? 118.618 124.874 85.501  1.00 27.09  ? 157 THR C CA  1 
ATOM   8722  C C   . THR C 1 157 ? 118.094 125.489 84.208  1.00 27.09  ? 157 THR C C   1 
ATOM   8723  O O   . THR C 1 157 ? 117.075 126.184 84.194  1.00 27.09  ? 157 THR C O   1 
ATOM   8724  C CB  . THR C 1 157 ? 118.819 123.360 85.344  1.00 27.09  ? 157 THR C CB  1 
ATOM   8725  O OG1 . THR C 1 157 ? 117.546 122.713 85.233  1.00 27.09  ? 157 THR C OG1 1 
ATOM   8726  C CG2 . THR C 1 157 ? 119.572 122.793 86.537  1.00 27.09  ? 157 THR C CG2 1 
ATOM   8727  N N   . LYS C 1 158 ? 118.802 125.232 83.113  1.00 30.00  ? 158 LYS C N   1 
ATOM   8728  C CA  . LYS C 1 158 ? 118.434 125.808 81.828  1.00 30.00  ? 158 LYS C CA  1 
ATOM   8729  C C   . LYS C 1 158 ? 117.111 125.235 81.331  1.00 30.00  ? 158 LYS C C   1 
ATOM   8730  O O   . LYS C 1 158 ? 116.736 124.102 81.644  1.00 30.00  ? 158 LYS C O   1 
ATOM   8731  C CB  . LYS C 1 158 ? 119.533 125.556 80.795  1.00 30.00  ? 158 LYS C CB  1 
ATOM   8732  C CG  . LYS C 1 158 ? 119.492 124.177 80.162  1.00 30.00  ? 158 LYS C CG  1 
ATOM   8733  C CD  . LYS C 1 158 ? 120.516 124.035 79.051  1.00 30.00  ? 158 LYS C CD  1 
ATOM   8734  C CE  . LYS C 1 158 ? 120.528 122.618 78.502  1.00 30.00  ? 158 LYS C CE  1 
ATOM   8735  N NZ  . LYS C 1 158 ? 121.628 122.400 77.525  1.00 30.00  ? 158 LYS C NZ  1 
ATOM   8736  N N   . SER C 1 159 ? 116.392 126.045 80.558  1.00 32.65  ? 159 SER C N   1 
ATOM   8737  C CA  . SER C 1 159 ? 115.149 125.637 79.916  1.00 32.65  ? 159 SER C CA  1 
ATOM   8738  C C   . SER C 1 159 ? 115.351 125.696 78.411  1.00 32.65  ? 159 SER C C   1 
ATOM   8739  O O   . SER C 1 159 ? 115.645 126.764 77.864  1.00 32.65  ? 159 SER C O   1 
ATOM   8740  C CB  . SER C 1 159 ? 113.984 126.533 80.339  1.00 32.65  ? 159 SER C CB  1 
ATOM   8741  O OG  . SER C 1 159 ? 112.767 126.087 79.769  1.00 32.65  ? 159 SER C OG  1 
ATOM   8742  N N   . GLY C 1 160 ? 115.189 124.558 77.745  1.00 33.83  ? 160 GLY C N   1 
ATOM   8743  C CA  . GLY C 1 160 ? 115.483 124.491 76.330  1.00 33.83  ? 160 GLY C CA  1 
ATOM   8744  C C   . GLY C 1 160 ? 116.975 124.521 76.079  1.00 33.83  ? 160 GLY C C   1 
ATOM   8745  O O   . GLY C 1 160 ? 117.674 123.538 76.338  1.00 33.83  ? 160 GLY C O   1 
ATOM   8746  N N   . SER C 1 161 ? 117.476 125.649 75.573  1.00 34.90  ? 161 SER C N   1 
ATOM   8747  C CA  . SER C 1 161 ? 118.903 125.817 75.326  1.00 34.90  ? 161 SER C CA  1 
ATOM   8748  C C   . SER C 1 161 ? 119.406 127.180 75.789  1.00 34.90  ? 161 SER C C   1 
ATOM   8749  O O   . SER C 1 161 ? 120.436 127.651 75.297  1.00 34.90  ? 161 SER C O   1 
ATOM   8750  C CB  . SER C 1 161 ? 119.221 125.616 73.843  1.00 34.90  ? 161 SER C CB  1 
ATOM   8751  O OG  . SER C 1 161 ? 118.593 126.608 73.050  1.00 34.90  ? 161 SER C OG  1 
ATOM   8752  N N   . SER C 1 162 ? 118.708 127.823 76.723  1.00 32.21  ? 162 SER C N   1 
ATOM   8753  C CA  . SER C 1 162 ? 119.080 129.153 77.179  1.00 32.21  ? 162 SER C CA  1 
ATOM   8754  C C   . SER C 1 162 ? 118.882 129.265 78.683  1.00 32.21  ? 162 SER C C   1 
ATOM   8755  O O   . SER C 1 162 ? 117.988 128.640 79.258  1.00 32.21  ? 162 SER C O   1 
ATOM   8756  C CB  . SER C 1 162 ? 118.265 130.239 76.466  1.00 32.21  ? 162 SER C CB  1 
ATOM   8757  O OG  . SER C 1 162 ? 116.879 130.077 76.709  1.00 32.21  ? 162 SER C OG  1 
ATOM   8758  N N   . TYR C 1 163 ? 119.731 130.074 79.311  1.00 27.16  ? 163 TYR C N   1 
ATOM   8759  C CA  . TYR C 1 163 ? 119.612 130.417 80.727  1.00 27.16  ? 163 TYR C CA  1 
ATOM   8760  C C   . TYR C 1 163 ? 119.632 131.936 80.828  1.00 27.16  ? 163 TYR C C   1 
ATOM   8761  O O   . TYR C 1 163 ? 120.716 132.543 80.881  1.00 27.16  ? 163 TYR C O   1 
ATOM   8762  C CB  . TYR C 1 163 ? 120.733 129.795 81.553  1.00 27.16  ? 163 TYR C CB  1 
ATOM   8763  C CG  . TYR C 1 163 ? 120.505 129.831 83.050  1.00 27.16  ? 163 TYR C CG  1 
ATOM   8764  C CD1 . TYR C 1 163 ? 120.649 131.010 83.770  1.00 27.16  ? 163 TYR C CD1 1 
ATOM   8765  C CD2 . TYR C 1 163 ? 120.149 128.684 83.744  1.00 27.16  ? 163 TYR C CD2 1 
ATOM   8766  C CE1 . TYR C 1 163 ? 120.440 131.044 85.135  1.00 27.16  ? 163 TYR C CE1 1 
ATOM   8767  C CE2 . TYR C 1 163 ? 119.940 128.709 85.108  1.00 27.16  ? 163 TYR C CE2 1 
ATOM   8768  C CZ  . TYR C 1 163 ? 120.087 129.891 85.799  1.00 27.16  ? 163 TYR C CZ  1 
ATOM   8769  O OH  . TYR C 1 163 ? 119.880 129.919 87.157  1.00 27.16  ? 163 TYR C OH  1 
ATOM   8770  N N   . PRO C 1 164 ? 118.471 132.585 80.849  1.00 28.69  ? 164 PRO C N   1 
ATOM   8771  C CA  . PRO C 1 164 ? 118.441 134.050 80.881  1.00 28.69  ? 164 PRO C CA  1 
ATOM   8772  C C   . PRO C 1 164 ? 118.879 134.585 82.235  1.00 28.69  ? 164 PRO C C   1 
ATOM   8773  O O   . PRO C 1 164 ? 118.990 133.861 83.226  1.00 28.69  ? 164 PRO C O   1 
ATOM   8774  C CB  . PRO C 1 164 ? 116.975 134.395 80.593  1.00 28.69  ? 164 PRO C CB  1 
ATOM   8775  C CG  . PRO C 1 164 ? 116.313 133.099 80.208  1.00 28.69  ? 164 PRO C CG  1 
ATOM   8776  C CD  . PRO C 1 164 ? 117.120 132.007 80.821  1.00 28.69  ? 164 PRO C CD  1 
ATOM   8777  N N   . LEU C 1 165 ? 119.135 135.890 82.261  1.00 25.87  ? 165 LEU C N   1 
ATOM   8778  C CA  . LEU C 1 165 ? 119.530 136.553 83.496  1.00 25.87  ? 165 LEU C CA  1 
ATOM   8779  C C   . LEU C 1 165 ? 118.321 136.713 84.409  1.00 25.87  ? 165 LEU C C   1 
ATOM   8780  O O   . LEU C 1 165 ? 117.289 137.254 84.002  1.00 25.87  ? 165 LEU C O   1 
ATOM   8781  C CB  . LEU C 1 165 ? 120.152 137.913 83.187  1.00 25.87  ? 165 LEU C CB  1 
ATOM   8782  C CG  . LEU C 1 165 ? 120.528 138.809 84.369  1.00 25.87  ? 165 LEU C CG  1 
ATOM   8783  C CD1 . LEU C 1 165 ? 121.828 138.350 85.002  1.00 25.87  ? 165 LEU C CD1 1 
ATOM   8784  C CD2 . LEU C 1 165 ? 120.631 140.257 83.926  1.00 25.87  ? 165 LEU C CD2 1 
ATOM   8785  N N   . LEU C 1 166 ? 118.450 136.241 85.645  1.00 25.53  ? 166 LEU C N   1 
ATOM   8786  C CA  . LEU C 1 166 ? 117.370 136.285 86.620  1.00 25.53  ? 166 LEU C CA  1 
ATOM   8787  C C   . LEU C 1 166 ? 117.517 137.525 87.489  1.00 25.53  ? 166 LEU C C   1 
ATOM   8788  O O   . LEU C 1 166 ? 118.600 137.793 88.020  1.00 25.53  ? 166 LEU C O   1 
ATOM   8789  C CB  . LEU C 1 166 ? 117.368 135.027 87.489  1.00 25.53  ? 166 LEU C CB  1 
ATOM   8790  C CG  . LEU C 1 166 ? 117.213 133.695 86.753  1.00 25.53  ? 166 LEU C CG  1 
ATOM   8791  C CD1 . LEU C 1 166 ? 117.580 132.541 87.665  1.00 25.53  ? 166 LEU C CD1 1 
ATOM   8792  C CD2 . LEU C 1 166 ? 115.798 133.535 86.225  1.00 25.53  ? 166 LEU C CD2 1 
ATOM   8793  N N   . ASN C 1 167 ? 116.426 138.277 87.633  1.00 27.61  ? 167 ASN C N   1 
ATOM   8794  C CA  . ASN C 1 167 ? 116.434 139.508 88.422  1.00 27.61  ? 167 ASN C CA  1 
ATOM   8795  C C   . ASN C 1 167 ? 115.040 139.670 89.022  1.00 27.61  ? 167 ASN C C   1 
ATOM   8796  O O   . ASN C 1 167 ? 114.113 140.105 88.333  1.00 27.61  ? 167 ASN C O   1 
ATOM   8797  C CB  . ASN C 1 167 ? 116.823 140.704 87.563  1.00 27.61  ? 167 ASN C CB  1 
ATOM   8798  C CG  . ASN C 1 167 ? 116.907 141.990 88.358  1.00 27.61  ? 167 ASN C CG  1 
ATOM   8799  O OD1 . ASN C 1 167 ? 117.606 142.065 89.367  1.00 27.61  ? 167 ASN C OD1 1 
ATOM   8800  N ND2 . ASN C 1 167 ? 116.193 143.012 87.905  1.00 27.61  ? 167 ASN C ND2 1 
ATOM   8801  N N   . VAL C 1 168 ? 114.901 139.319 90.302  1.00 25.63  ? 168 VAL C N   1 
ATOM   8802  C CA  . VAL C 1 168 ? 113.620 139.354 90.994  1.00 25.63  ? 168 VAL C CA  1 
ATOM   8803  C C   . VAL C 1 168 ? 113.763 140.185 92.262  1.00 25.63  ? 168 VAL C C   1 
ATOM   8804  O O   . VAL C 1 168 ? 114.867 140.458 92.737  1.00 25.63  ? 168 VAL C O   1 
ATOM   8805  C CB  . VAL C 1 168 ? 113.096 137.941 91.339  1.00 25.63  ? 168 VAL C CB  1 
ATOM   8806  C CG1 . VAL C 1 168 ? 113.148 137.035 90.121  1.00 25.63  ? 168 VAL C CG1 1 
ATOM   8807  C CG2 . VAL C 1 168 ? 113.892 137.345 92.487  1.00 25.63  ? 168 VAL C CG2 1 
ATOM   8808  N N   . THR C 1 169 ? 112.617 140.592 92.806  1.00 27.25  ? 169 THR C N   1 
ATOM   8809  C CA  . THR C 1 169 ? 112.577 141.401 94.016  1.00 27.25  ? 169 THR C CA  1 
ATOM   8810  C C   . THR C 1 169 ? 111.456 140.910 94.922  1.00 27.25  ? 169 THR C C   1 
ATOM   8811  O O   . THR C 1 169 ? 110.496 140.277 94.475  1.00 27.25  ? 169 THR C O   1 
ATOM   8812  C CB  . THR C 1 169 ? 112.387 142.890 93.696  1.00 27.25  ? 169 THR C CB  1 
ATOM   8813  O OG1 . THR C 1 169 ? 112.447 143.653 94.906  1.00 27.25  ? 169 THR C OG1 1 
ATOM   8814  C CG2 . THR C 1 169 ? 111.047 143.127 93.021  1.00 27.25  ? 169 THR C CG2 1 
ATOM   8815  N N   . MET C 1 170 ? 111.597 141.203 96.215  1.00 26.69  ? 170 MET C N   1 
ATOM   8816  C CA  . MET C 1 170 ? 110.606 140.830 97.217  1.00 26.69  ? 170 MET C CA  1 
ATOM   8817  C C   . MET C 1 170 ? 110.682 141.780 98.407  1.00 26.69  ? 170 MET C C   1 
ATOM   8818  O O   . MET C 1 170 ? 111.687 141.789 99.129  1.00 26.69  ? 170 MET C O   1 
ATOM   8819  C CB  . MET C 1 170 ? 110.818 139.384 97.668  1.00 26.69  ? 170 MET C CB  1 
ATOM   8820  C CG  . MET C 1 170 ? 109.735 138.848 98.592  1.00 26.69  ? 170 MET C CG  1 
ATOM   8821  S SD  . MET C 1 170 ? 108.169 138.553 97.750  1.00 26.69  ? 170 MET C SD  1 
ATOM   8822  C CE  . MET C 1 170 ? 108.618 137.221 96.643  1.00 26.69  ? 170 MET C CE  1 
ATOM   8823  N N   . PRO C 1 171 ? 109.651 142.586 98.648  1.00 27.07  ? 171 PRO C N   1 
ATOM   8824  C CA  . PRO C 1 171 ? 109.690 143.541 99.757  1.00 27.07  ? 171 PRO C CA  1 
ATOM   8825  C C   . PRO C 1 171 ? 109.168 142.960 101.061 1.00 27.07  ? 171 PRO C C   1 
ATOM   8826  O O   . PRO C 1 171 ? 108.340 142.048 101.090 1.00 27.07  ? 171 PRO C O   1 
ATOM   8827  C CB  . PRO C 1 171 ? 108.779 144.677 99.266  1.00 27.07  ? 171 PRO C CB  1 
ATOM   8828  C CG  . PRO C 1 171 ? 107.966 144.097 98.123  1.00 27.07  ? 171 PRO C CG  1 
ATOM   8829  C CD  . PRO C 1 171 ? 108.396 142.681 97.888  1.00 27.07  ? 171 PRO C CD  1 
ATOM   8830  N N   . ASN C 1 172 ? 109.674 143.517 102.160 1.00 26.68  ? 172 ASN C N   1 
ATOM   8831  C CA  . ASN C 1 172 ? 109.275 143.122 103.509 1.00 26.68  ? 172 ASN C CA  1 
ATOM   8832  C C   . ASN C 1 172 ? 108.224 144.114 103.994 1.00 26.68  ? 172 ASN C C   1 
ATOM   8833  O O   . ASN C 1 172 ? 108.555 145.190 104.498 1.00 26.68  ? 172 ASN C O   1 
ATOM   8834  C CB  . ASN C 1 172 ? 110.482 143.079 104.442 1.00 26.68  ? 172 ASN C CB  1 
ATOM   8835  C CG  . ASN C 1 172 ? 110.158 142.467 105.794 1.00 26.68  ? 172 ASN C CG  1 
ATOM   8836  O OD1 . ASN C 1 172 ? 109.005 142.168 106.096 1.00 26.68  ? 172 ASN C OD1 1 
ATOM   8837  N ND2 . ASN C 1 172 ? 111.182 142.276 106.614 1.00 26.68  ? 172 ASN C ND2 1 
ATOM   8838  N N   . ASN C 1 173 ? 106.953 143.748 103.841 1.00 31.12  ? 173 ASN C N   1 
ATOM   8839  C CA  . ASN C 1 173 ? 105.840 144.600 104.235 1.00 31.12  ? 173 ASN C CA  1 
ATOM   8840  C C   . ASN C 1 173 ? 105.242 144.205 105.579 1.00 31.12  ? 173 ASN C C   1 
ATOM   8841  O O   . ASN C 1 173 ? 104.202 144.747 105.966 1.00 31.12  ? 173 ASN C O   1 
ATOM   8842  C CB  . ASN C 1 173 ? 104.758 144.583 103.155 1.00 31.12  ? 173 ASN C CB  1 
ATOM   8843  C CG  . ASN C 1 173 ? 105.188 145.296 101.888 1.00 31.12  ? 173 ASN C CG  1 
ATOM   8844  O OD1 . ASN C 1 173 ? 105.876 146.313 101.938 1.00 31.12  ? 173 ASN C OD1 1 
ATOM   8845  N ND2 . ASN C 1 173 ? 104.780 144.763 100.742 1.00 31.12  ? 173 ASN C ND2 1 
ATOM   8846  N N   . TYR C 1 174 ? 105.867 143.274 106.294 1.00 31.88  ? 174 TYR C N   1 
ATOM   8847  C CA  . TYR C 1 174 ? 105.409 142.875 107.615 1.00 31.88  ? 174 TYR C CA  1 
ATOM   8848  C C   . TYR C 1 174 ? 106.108 143.726 108.673 1.00 31.88  ? 174 TYR C C   1 
ATOM   8849  O O   . TYR C 1 174 ? 106.766 144.724 108.367 1.00 31.88  ? 174 TYR C O   1 
ATOM   8850  C CB  . TYR C 1 174 ? 105.657 141.386 107.840 1.00 31.88  ? 174 TYR C CB  1 
ATOM   8851  C CG  . TYR C 1 174 ? 105.011 140.482 106.817 1.00 31.88  ? 174 TYR C CG  1 
ATOM   8852  C CD1 . TYR C 1 174 ? 103.681 140.642 106.457 1.00 31.88  ? 174 TYR C CD1 1 
ATOM   8853  C CD2 . TYR C 1 174 ? 105.733 139.463 106.214 1.00 31.88  ? 174 TYR C CD2 1 
ATOM   8854  C CE1 . TYR C 1 174 ? 103.091 139.814 105.523 1.00 31.88  ? 174 TYR C CE1 1 
ATOM   8855  C CE2 . TYR C 1 174 ? 105.153 138.631 105.280 1.00 31.88  ? 174 TYR C CE2 1 
ATOM   8856  C CZ  . TYR C 1 174 ? 103.832 138.810 104.938 1.00 31.88  ? 174 TYR C CZ  1 
ATOM   8857  O OH  . TYR C 1 174 ? 103.253 137.980 104.006 1.00 31.88  ? 174 TYR C OH  1 
ATOM   8858  N N   . ASN C 1 175 ? 105.974 143.334 109.941 1.00 33.38  ? 175 ASN C N   1 
ATOM   8859  C CA  . ASN C 1 175 ? 106.620 144.032 111.047 1.00 33.38  ? 175 ASN C CA  1 
ATOM   8860  C C   . ASN C 1 175 ? 107.583 143.132 111.816 1.00 33.38  ? 175 ASN C C   1 
ATOM   8861  O O   . ASN C 1 175 ? 107.816 143.355 113.008 1.00 33.38  ? 175 ASN C O   1 
ATOM   8862  C CB  . ASN C 1 175 ? 105.569 144.637 111.983 1.00 33.38  ? 175 ASN C CB  1 
ATOM   8863  C CG  . ASN C 1 175 ? 104.694 143.588 112.658 1.00 33.38  ? 175 ASN C CG  1 
ATOM   8864  O OD1 . ASN C 1 175 ? 104.926 142.385 112.538 1.00 33.38  ? 175 ASN C OD1 1 
ATOM   8865  N ND2 . ASN C 1 175 ? 103.677 144.049 113.374 1.00 33.38  ? 175 ASN C ND2 1 
ATOM   8866  N N   . PHE C 1 176 ? 108.150 142.124 111.157 1.00 29.31  ? 176 PHE C N   1 
ATOM   8867  C CA  . PHE C 1 176 ? 109.120 141.232 111.775 1.00 29.31  ? 176 PHE C CA  1 
ATOM   8868  C C   . PHE C 1 176 ? 110.226 140.932 110.773 1.00 29.31  ? 176 PHE C C   1 
ATOM   8869  O O   . PHE C 1 176 ? 110.074 141.134 109.565 1.00 29.31  ? 176 PHE C O   1 
ATOM   8870  C CB  . PHE C 1 176 ? 108.463 139.935 112.268 1.00 29.31  ? 176 PHE C CB  1 
ATOM   8871  C CG  . PHE C 1 176 ? 107.536 139.302 111.269 1.00 29.31  ? 176 PHE C CG  1 
ATOM   8872  C CD1 . PHE C 1 176 ? 108.031 138.504 110.251 1.00 29.31  ? 176 PHE C CD1 1 
ATOM   8873  C CD2 . PHE C 1 176 ? 106.169 139.498 111.353 1.00 29.31  ? 176 PHE C CD2 1 
ATOM   8874  C CE1 . PHE C 1 176 ? 107.181 137.921 109.334 1.00 29.31  ? 176 PHE C CE1 1 
ATOM   8875  C CE2 . PHE C 1 176 ? 105.314 138.917 110.440 1.00 29.31  ? 176 PHE C CE2 1 
ATOM   8876  C CZ  . PHE C 1 176 ? 105.822 138.128 109.429 1.00 29.31  ? 176 PHE C CZ  1 
ATOM   8877  N N   . ASP C 1 177 ? 111.352 140.448 111.289 1.00 26.77  ? 177 ASP C N   1 
ATOM   8878  C CA  . ASP C 1 177 ? 112.490 140.107 110.450 1.00 26.77  ? 177 ASP C CA  1 
ATOM   8879  C C   . ASP C 1 177 ? 112.212 138.842 109.645 1.00 26.77  ? 177 ASP C C   1 
ATOM   8880  O O   . ASP C 1 177 ? 111.451 137.965 110.064 1.00 26.77  ? 177 ASP C O   1 
ATOM   8881  C CB  . ASP C 1 177 ? 113.745 139.907 111.300 1.00 26.77  ? 177 ASP C CB  1 
ATOM   8882  C CG  . ASP C 1 177 ? 114.190 141.177 111.992 1.00 26.77  ? 177 ASP C CG  1 
ATOM   8883  O OD1 . ASP C 1 177 ? 113.480 142.196 111.887 1.00 26.77  ? 177 ASP C OD1 1 
ATOM   8884  O OD2 . ASP C 1 177 ? 115.251 141.153 112.649 1.00 26.77  ? 177 ASP C OD2 1 
ATOM   8885  N N   . LYS C 1 178 ? 112.846 138.754 108.478 1.00 22.17  ? 178 LYS C N   1 
ATOM   8886  C CA  . LYS C 1 178 ? 112.739 137.601 107.596 1.00 22.17  ? 178 LYS C CA  1 
ATOM   8887  C C   . LYS C 1 178 ? 114.110 136.965 107.421 1.00 22.17  ? 178 LYS C C   1 
ATOM   8888  O O   . LYS C 1 178 ? 115.113 137.668 107.273 1.00 22.17  ? 178 LYS C O   1 
ATOM   8889  C CB  . LYS C 1 178 ? 112.187 137.995 106.224 1.00 22.17  ? 178 LYS C CB  1 
ATOM   8890  C CG  . LYS C 1 178 ? 110.737 138.427 106.214 1.00 22.17  ? 178 LYS C CG  1 
ATOM   8891  C CD  . LYS C 1 178 ? 110.324 138.836 104.814 1.00 22.17  ? 178 LYS C CD  1 
ATOM   8892  C CE  . LYS C 1 178 ? 108.819 138.898 104.669 1.00 22.17  ? 178 LYS C CE  1 
ATOM   8893  N NZ  . LYS C 1 178 ? 108.418 139.118 103.254 1.00 22.17  ? 178 LYS C NZ  1 
ATOM   8894  N N   . LEU C 1 179 ? 114.151 135.636 107.435 1.00 19.00  ? 179 LEU C N   1 
ATOM   8895  C CA  . LEU C 1 179 ? 115.382 134.885 107.225 1.00 19.00  ? 179 LEU C CA  1 
ATOM   8896  C C   . LEU C 1 179 ? 115.256 134.079 105.940 1.00 19.00  ? 179 LEU C C   1 
ATOM   8897  O O   . LEU C 1 179 ? 114.335 133.269 105.801 1.00 19.00  ? 179 LEU C O   1 
ATOM   8898  C CB  . LEU C 1 179 ? 115.675 133.966 108.412 1.00 19.00  ? 179 LEU C CB  1 
ATOM   8899  C CG  . LEU C 1 179 ? 116.908 133.071 108.292 1.00 19.00  ? 179 LEU C CG  1 
ATOM   8900  C CD1 . LEU C 1 179 ? 118.182 133.893 108.355 1.00 19.00  ? 179 LEU C CD1 1 
ATOM   8901  C CD2 . LEU C 1 179 ? 116.898 132.018 109.379 1.00 19.00  ? 179 LEU C CD2 1 
ATOM   8902  N N   . TYR C 1 180 ? 116.183 134.297 105.012 1.00 18.45  ? 180 TYR C N   1 
ATOM   8903  C CA  . TYR C 1 180 ? 116.198 133.612 103.728 1.00 18.45  ? 180 TYR C CA  1 
ATOM   8904  C C   . TYR C 1 180 ? 117.410 132.695 103.647 1.00 18.45  ? 180 TYR C C   1 
ATOM   8905  O O   . TYR C 1 180 ? 118.510 133.072 104.055 1.00 18.45  ? 180 TYR C O   1 
ATOM   8906  C CB  . TYR C 1 180 ? 116.233 134.612 102.569 1.00 18.45  ? 180 TYR C CB  1 
ATOM   8907  C CG  . TYR C 1 180 ? 114.913 135.286 102.285 1.00 18.45  ? 180 TYR C CG  1 
ATOM   8908  C CD1 . TYR C 1 180 ? 113.995 134.716 101.417 1.00 18.45  ? 180 TYR C CD1 1 
ATOM   8909  C CD2 . TYR C 1 180 ? 114.587 136.497 102.879 1.00 18.45  ? 180 TYR C CD2 1 
ATOM   8910  C CE1 . TYR C 1 180 ? 112.790 135.329 101.150 1.00 18.45  ? 180 TYR C CE1 1 
ATOM   8911  C CE2 . TYR C 1 180 ? 113.384 137.117 102.618 1.00 18.45  ? 180 TYR C CE2 1 
ATOM   8912  C CZ  . TYR C 1 180 ? 112.489 136.529 101.754 1.00 18.45  ? 180 TYR C CZ  1 
ATOM   8913  O OH  . TYR C 1 180 ? 111.288 137.141 101.489 1.00 18.45  ? 180 TYR C OH  1 
ATOM   8914  N N   . ILE C 1 181 ? 117.203 131.491 103.120 1.00 17.51  ? 181 ILE C N   1 
ATOM   8915  C CA  . ILE C 1 181 ? 118.268 130.517 102.918 1.00 17.51  ? 181 ILE C CA  1 
ATOM   8916  C C   . ILE C 1 181 ? 118.365 130.222 101.428 1.00 17.51  ? 181 ILE C C   1 
ATOM   8917  O O   . ILE C 1 181 ? 117.369 129.848 100.800 1.00 17.51  ? 181 ILE C O   1 
ATOM   8918  C CB  . ILE C 1 181 ? 118.022 129.224 103.717 1.00 17.51  ? 181 ILE C CB  1 
ATOM   8919  C CG1 . ILE C 1 181 ? 117.665 129.545 105.171 1.00 17.51  ? 181 ILE C CG1 1 
ATOM   8920  C CG2 . ILE C 1 181 ? 119.236 128.313 103.647 1.00 17.51  ? 181 ILE C CG2 1 
ATOM   8921  C CD1 . ILE C 1 181 ? 118.840 129.975 106.016 1.00 17.51  ? 181 ILE C CD1 1 
ATOM   8922  N N   . TRP C 1 182 ? 119.562 130.387 100.869 1.00 16.49  ? 182 TRP C N   1 
ATOM   8923  C CA  . TRP C 1 182 ? 119.809 130.150 99.454  1.00 16.49  ? 182 TRP C CA  1 
ATOM   8924  C C   . TRP C 1 182 ? 121.144 129.430 99.311  1.00 16.49  ? 182 TRP C C   1 
ATOM   8925  O O   . TRP C 1 182 ? 121.855 129.200 100.293 1.00 16.49  ? 182 TRP C O   1 
ATOM   8926  C CB  . TRP C 1 182 ? 119.779 131.461 98.657  1.00 16.49  ? 182 TRP C CB  1 
ATOM   8927  C CG  . TRP C 1 182 ? 120.546 132.585 99.290  1.00 16.49  ? 182 TRP C CG  1 
ATOM   8928  C CD1 . TRP C 1 182 ? 120.142 133.371 100.328 1.00 16.49  ? 182 TRP C CD1 1 
ATOM   8929  C CD2 . TRP C 1 182 ? 121.844 133.055 98.914  1.00 16.49  ? 182 TRP C CD2 1 
ATOM   8930  N NE1 . TRP C 1 182 ? 121.110 134.295 100.628 1.00 16.49  ? 182 TRP C NE1 1 
ATOM   8931  C CE2 . TRP C 1 182 ? 122.167 134.123 99.773  1.00 16.49  ? 182 TRP C CE2 1 
ATOM   8932  C CE3 . TRP C 1 182 ? 122.768 132.674 97.936  1.00 16.49  ? 182 TRP C CE3 1 
ATOM   8933  C CZ2 . TRP C 1 182 ? 123.371 134.815 99.683  1.00 16.49  ? 182 TRP C CZ2 1 
ATOM   8934  C CZ3 . TRP C 1 182 ? 123.961 133.362 97.848  1.00 16.49  ? 182 TRP C CZ3 1 
ATOM   8935  C CH2 . TRP C 1 182 ? 124.253 134.420 98.717  1.00 16.49  ? 182 TRP C CH2 1 
ATOM   8936  N N   . GLY C 1 183 ? 121.491 129.071 98.074  1.00 18.35  ? 183 GLY C N   1 
ATOM   8937  C CA  . GLY C 1 183 ? 122.698 128.305 97.846  1.00 18.35  ? 183 GLY C CA  1 
ATOM   8938  C C   . GLY C 1 183 ? 123.289 128.516 96.469  1.00 18.35  ? 183 GLY C C   1 
ATOM   8939  O O   . GLY C 1 183 ? 122.680 129.125 95.587  1.00 18.35  ? 183 GLY C O   1 
ATOM   8940  N N   . VAL C 1 184 ? 124.507 128.000 96.305  1.00 20.03  ? 184 VAL C N   1 
ATOM   8941  C CA  . VAL C 1 184 ? 125.245 128.044 95.048  1.00 20.03  ? 184 VAL C CA  1 
ATOM   8942  C C   . VAL C 1 184 ? 125.760 126.643 94.747  1.00 20.03  ? 184 VAL C C   1 
ATOM   8943  O O   . VAL C 1 184 ? 126.289 125.965 95.634  1.00 20.03  ? 184 VAL C O   1 
ATOM   8944  C CB  . VAL C 1 184 ? 126.416 129.051 95.101  1.00 20.03  ? 184 VAL C CB  1 
ATOM   8945  C CG1 . VAL C 1 184 ? 127.083 129.169 93.741  1.00 20.03  ? 184 VAL C CG1 1 
ATOM   8946  C CG2 . VAL C 1 184 ? 125.937 130.412 95.576  1.00 20.03  ? 184 VAL C CG2 1 
ATOM   8947  N N   . HIS C 1 185 ? 125.608 126.211 93.498  1.00 21.17  ? 185 HIS C N   1 
ATOM   8948  C CA  . HIS C 1 185 ? 126.034 124.885 93.067  1.00 21.17  ? 185 HIS C CA  1 
ATOM   8949  C C   . HIS C 1 185 ? 127.428 124.957 92.458  1.00 21.17  ? 185 HIS C C   1 
ATOM   8950  O O   . HIS C 1 185 ? 127.695 125.810 91.605  1.00 21.17  ? 185 HIS C O   1 
ATOM   8951  C CB  . HIS C 1 185 ? 125.048 124.297 92.056  1.00 21.17  ? 185 HIS C CB  1 
ATOM   8952  C CG  . HIS C 1 185 ? 125.376 122.898 91.634  1.00 21.17  ? 185 HIS C CG  1 
ATOM   8953  N ND1 . HIS C 1 185 ? 125.493 122.528 90.312  1.00 21.17  ? 185 HIS C ND1 1 
ATOM   8954  C CD2 . HIS C 1 185 ? 125.611 121.779 92.359  1.00 21.17  ? 185 HIS C CD2 1 
ATOM   8955  C CE1 . HIS C 1 185 ? 125.788 121.242 90.241  1.00 21.17  ? 185 HIS C CE1 1 
ATOM   8956  N NE2 . HIS C 1 185 ? 125.864 120.764 91.469  1.00 21.17  ? 185 HIS C NE2 1 
ATOM   8957  N N   . HIS C 1 186 ? 128.311 124.059 92.895  1.00 21.95  ? 186 HIS C N   1 
ATOM   8958  C CA  . HIS C 1 186 ? 129.679 123.987 92.389  1.00 21.95  ? 186 HIS C CA  1 
ATOM   8959  C C   . HIS C 1 186 ? 129.842 122.735 91.537  1.00 21.95  ? 186 HIS C C   1 
ATOM   8960  O O   . HIS C 1 186 ? 129.959 121.627 92.081  1.00 21.95  ? 186 HIS C O   1 
ATOM   8961  C CB  . HIS C 1 186 ? 130.685 123.979 93.544  1.00 21.95  ? 186 HIS C CB  1 
ATOM   8962  C CG  . HIS C 1 186 ? 130.528 125.124 94.495  1.00 21.95  ? 186 HIS C CG  1 
ATOM   8963  N ND1 . HIS C 1 186 ? 130.900 126.411 94.178  1.00 21.95  ? 186 HIS C ND1 1 
ATOM   8964  C CD2 . HIS C 1 186 ? 130.050 125.172 95.761  1.00 21.95  ? 186 HIS C CD2 1 
ATOM   8965  C CE1 . HIS C 1 186 ? 130.653 127.205 95.204  1.00 21.95  ? 186 HIS C CE1 1 
ATOM   8966  N NE2 . HIS C 1 186 ? 130.135 126.478 96.177  1.00 21.95  ? 186 HIS C NE2 1 
ATOM   8967  N N   . PRO C 1 187 ? 129.865 122.850 90.212  1.00 23.82  ? 187 PRO C N   1 
ATOM   8968  C CA  . PRO C 1 187 ? 130.011 121.660 89.366  1.00 23.82  ? 187 PRO C CA  1 
ATOM   8969  C C   . PRO C 1 187 ? 131.415 121.079 89.458  1.00 23.82  ? 187 PRO C C   1 
ATOM   8970  O O   . PRO C 1 187 ? 132.342 121.679 90.001  1.00 23.82  ? 187 PRO C O   1 
ATOM   8971  C CB  . PRO C 1 187 ? 129.711 122.181 87.955  1.00 23.82  ? 187 PRO C CB  1 
ATOM   8972  C CG  . PRO C 1 187 ? 129.041 123.503 88.156  1.00 23.82  ? 187 PRO C CG  1 
ATOM   8973  C CD  . PRO C 1 187 ? 129.614 124.060 89.415  1.00 23.82  ? 187 PRO C CD  1 
ATOM   8974  N N   . SER C 1 188 ? 131.558 119.871 88.910  1.00 25.86  ? 188 SER C N   1 
ATOM   8975  C CA  . SER C 1 188 ? 132.823 119.152 88.960  1.00 25.86  ? 188 SER C CA  1 
ATOM   8976  C C   . SER C 1 188 ? 133.645 119.273 87.684  1.00 25.86  ? 188 SER C C   1 
ATOM   8977  O O   . SER C 1 188 ? 134.865 119.087 87.737  1.00 25.86  ? 188 SER C O   1 
ATOM   8978  C CB  . SER C 1 188 ? 132.578 117.668 89.259  1.00 25.86  ? 188 SER C CB  1 
ATOM   8979  O OG  . SER C 1 188 ? 131.686 117.098 88.319  1.00 25.86  ? 188 SER C OG  1 
ATOM   8980  N N   . THR C 1 189 ? 133.020 119.577 86.549  1.00 28.05  ? 189 THR C N   1 
ATOM   8981  C CA  . THR C 1 189 ? 133.735 119.738 85.291  1.00 28.05  ? 189 THR C CA  1 
ATOM   8982  C C   . THR C 1 189 ? 133.192 120.952 84.554  1.00 28.05  ? 189 THR C C   1 
ATOM   8983  O O   . THR C 1 189 ? 132.105 121.453 84.853  1.00 28.05  ? 189 THR C O   1 
ATOM   8984  C CB  . THR C 1 189 ? 133.622 118.494 84.393  1.00 28.05  ? 189 THR C CB  1 
ATOM   8985  O OG1 . THR C 1 189 ? 132.242 118.185 84.166  1.00 28.05  ? 189 THR C OG1 1 
ATOM   8986  C CG2 . THR C 1 189 ? 134.310 117.296 85.030  1.00 28.05  ? 189 THR C CG2 1 
ATOM   8987  N N   . ASN C 1 190 ? 133.975 121.429 83.584  1.00 29.44  ? 190 ASN C N   1 
ATOM   8988  C CA  . ASN C 1 190 ? 133.521 122.525 82.733  1.00 29.44  ? 190 ASN C CA  1 
ATOM   8989  C C   . ASN C 1 190 ? 132.368 122.086 81.839  1.00 29.44  ? 190 ASN C C   1 
ATOM   8990  O O   . ASN C 1 190 ? 131.433 122.859 81.595  1.00 29.44  ? 190 ASN C O   1 
ATOM   8991  C CB  . ASN C 1 190 ? 134.684 123.049 81.891  1.00 29.44  ? 190 ASN C CB  1 
ATOM   8992  C CG  . ASN C 1 190 ? 135.493 124.109 82.610  1.00 29.44  ? 190 ASN C CG  1 
ATOM   8993  O OD1 . ASN C 1 190 ? 135.364 124.293 83.818  1.00 29.44  ? 190 ASN C OD1 1 
ATOM   8994  N ND2 . ASN C 1 190 ? 136.340 124.810 81.867  1.00 29.44  ? 190 ASN C ND2 1 
ATOM   8995  N N   . GLN C 1 191 ? 132.423 120.851 81.336  1.00 32.12  ? 191 GLN C N   1 
ATOM   8996  C CA  . GLN C 1 191 ? 131.348 120.344 80.490  1.00 32.12  ? 191 GLN C CA  1 
ATOM   8997  C C   . GLN C 1 191 ? 130.034 120.269 81.255  1.00 32.12  ? 191 GLN C C   1 
ATOM   8998  O O   . GLN C 1 191 ? 128.978 120.618 80.721  1.00 32.12  ? 191 GLN C O   1 
ATOM   8999  C CB  . GLN C 1 191 ? 131.725 118.973 79.930  1.00 32.12  ? 191 GLN C CB  1 
ATOM   9000  C CG  . GLN C 1 191 ? 130.700 118.386 78.974  1.00 32.12  ? 191 GLN C CG  1 
ATOM   9001  C CD  . GLN C 1 191 ? 130.504 119.236 77.733  1.00 32.12  ? 191 GLN C CD  1 
ATOM   9002  O OE1 . GLN C 1 191 ? 129.501 119.936 77.598  1.00 32.12  ? 191 GLN C OE1 1 
ATOM   9003  N NE2 . GLN C 1 191 ? 131.465 119.179 76.819  1.00 32.12  ? 191 GLN C NE2 1 
ATOM   9004  N N   . GLU C 1 192 ? 130.081 119.817 82.511  1.00 29.18  ? 192 GLU C N   1 
ATOM   9005  C CA  . GLU C 1 192 ? 128.874 119.787 83.332  1.00 29.18  ? 192 GLU C CA  1 
ATOM   9006  C C   . GLU C 1 192 ? 128.344 121.192 83.586  1.00 29.18  ? 192 GLU C C   1 
ATOM   9007  O O   . GLU C 1 192 ? 127.129 121.421 83.556  1.00 29.18  ? 192 GLU C O   1 
ATOM   9008  C CB  . GLU C 1 192 ? 129.160 119.075 84.654  1.00 29.18  ? 192 GLU C CB  1 
ATOM   9009  C CG  . GLU C 1 192 ? 127.950 118.928 85.555  1.00 29.18  ? 192 GLU C CG  1 
ATOM   9010  C CD  . GLU C 1 192 ? 128.325 118.896 87.022  1.00 29.18  ? 192 GLU C CD  1 
ATOM   9011  O OE1 . GLU C 1 192 ? 129.530 118.796 87.325  1.00 29.18  ? 192 GLU C OE1 1 
ATOM   9012  O OE2 . GLU C 1 192 ? 127.415 118.973 87.871  1.00 29.18  ? 192 GLU C OE2 1 
ATOM   9013  N N   . GLN C 1 193 ? 129.244 122.144 83.845  1.00 27.40  ? 193 GLN C N   1 
ATOM   9014  C CA  . GLN C 1 193 ? 128.825 123.523 84.070  1.00 27.40  ? 193 GLN C CA  1 
ATOM   9015  C C   . GLN C 1 193 ? 128.128 124.093 82.842  1.00 27.40  ? 193 GLN C C   1 
ATOM   9016  O O   . GLN C 1 193 ? 127.101 124.769 82.962  1.00 27.40  ? 193 GLN C O   1 
ATOM   9017  C CB  . GLN C 1 193 ? 130.032 124.380 84.451  1.00 27.40  ? 193 GLN C CB  1 
ATOM   9018  C CG  . GLN C 1 193 ? 129.896 125.850 84.091  1.00 27.40  ? 193 GLN C CG  1 
ATOM   9019  C CD  . GLN C 1 193 ? 129.163 126.647 85.149  1.00 27.40  ? 193 GLN C CD  1 
ATOM   9020  O OE1 . GLN C 1 193 ? 129.370 126.451 86.344  1.00 27.40  ? 193 GLN C OE1 1 
ATOM   9021  N NE2 . GLN C 1 193 ? 128.299 127.554 84.713  1.00 27.40  ? 193 GLN C NE2 1 
ATOM   9022  N N   . THR C 1 194 ? 128.668 123.823 81.651  1.00 29.60  ? 194 THR C N   1 
ATOM   9023  C CA  . THR C 1 194 ? 128.042 124.317 80.429  1.00 29.60  ? 194 THR C CA  1 
ATOM   9024  C C   . THR C 1 194 ? 126.743 123.578 80.121  1.00 29.60  ? 194 THR C C   1 
ATOM   9025  O O   . THR C 1 194 ? 125.808 124.171 79.570  1.00 29.60  ? 194 THR C O   1 
ATOM   9026  C CB  . THR C 1 194 ? 129.020 124.200 79.258  1.00 29.60  ? 194 THR C CB  1 
ATOM   9027  O OG1 . THR C 1 194 ? 130.204 124.952 79.550  1.00 29.60  ? 194 THR C OG1 1 
ATOM   9028  C CG2 . THR C 1 194 ? 128.402 124.738 77.978  1.00 29.60  ? 194 THR C CG2 1 
ATOM   9029  N N   . ASN C 1 195 ? 126.655 122.295 80.479  1.00 31.18  ? 195 ASN C N   1 
ATOM   9030  C CA  . ASN C 1 195 ? 125.459 121.521 80.168  1.00 31.18  ? 195 ASN C CA  1 
ATOM   9031  C C   . ASN C 1 195 ? 124.294 121.919 81.067  1.00 31.18  ? 195 ASN C C   1 
ATOM   9032  O O   . ASN C 1 195 ? 123.160 122.060 80.594  1.00 31.18  ? 195 ASN C O   1 
ATOM   9033  C CB  . ASN C 1 195 ? 125.766 120.028 80.301  1.00 31.18  ? 195 ASN C CB  1 
ATOM   9034  C CG  . ASN C 1 195 ? 124.642 119.144 79.793  1.00 31.18  ? 195 ASN C CG  1 
ATOM   9035  O OD1 . ASN C 1 195 ? 123.599 119.626 79.354  1.00 31.18  ? 195 ASN C OD1 1 
ATOM   9036  N ND2 . ASN C 1 195 ? 124.854 117.836 79.852  1.00 31.18  ? 195 ASN C ND2 1 
ATOM   9037  N N   . LEU C 1 196 ? 124.548 122.110 82.364  1.00 27.18  ? 196 LEU C N   1 
ATOM   9038  C CA  . LEU C 1 196 ? 123.473 122.511 83.266  1.00 27.18  ? 196 LEU C CA  1 
ATOM   9039  C C   . LEU C 1 196 ? 123.099 123.974 83.070  1.00 27.18  ? 196 LEU C C   1 
ATOM   9040  O O   . LEU C 1 196 ? 121.914 124.326 83.089  1.00 27.18  ? 196 LEU C O   1 
ATOM   9041  C CB  . LEU C 1 196 ? 123.874 122.252 84.718  1.00 27.18  ? 196 LEU C CB  1 
ATOM   9042  C CG  . LEU C 1 196 ? 124.046 120.794 85.145  1.00 27.18  ? 196 LEU C CG  1 
ATOM   9043  C CD1 . LEU C 1 196 ? 124.150 120.696 86.655  1.00 27.18  ? 196 LEU C CD1 1 
ATOM   9044  C CD2 . LEU C 1 196 ? 122.897 119.944 84.629  1.00 27.18  ? 196 LEU C CD2 1 
ATOM   9045  N N   . TYR C 1 197 ? 124.092 124.840 82.884  1.00 26.27  ? 197 TYR C N   1 
ATOM   9046  C CA  . TYR C 1 197 ? 123.879 126.270 82.717  1.00 26.27  ? 197 TYR C CA  1 
ATOM   9047  C C   . TYR C 1 197 ? 124.607 126.705 81.456  1.00 26.27  ? 197 TYR C C   1 
ATOM   9048  O O   . TYR C 1 197 ? 125.779 126.369 81.272  1.00 26.27  ? 197 TYR C O   1 
ATOM   9049  C CB  . TYR C 1 197 ? 124.397 127.044 83.932  1.00 26.27  ? 197 TYR C CB  1 
ATOM   9050  C CG  . TYR C 1 197 ? 124.059 126.375 85.244  1.00 26.27  ? 197 TYR C CG  1 
ATOM   9051  C CD1 . TYR C 1 197 ? 122.779 126.440 85.775  1.00 26.27  ? 197 TYR C CD1 1 
ATOM   9052  C CD2 . TYR C 1 197 ? 125.021 125.656 85.940  1.00 26.27  ? 197 TYR C CD2 1 
ATOM   9053  C CE1 . TYR C 1 197 ? 122.471 125.818 86.969  1.00 26.27  ? 197 TYR C CE1 1 
ATOM   9054  C CE2 . TYR C 1 197 ? 124.722 125.031 87.132  1.00 26.27  ? 197 TYR C CE2 1 
ATOM   9055  C CZ  . TYR C 1 197 ? 123.447 125.115 87.642  1.00 26.27  ? 197 TYR C CZ  1 
ATOM   9056  O OH  . TYR C 1 197 ? 123.152 124.494 88.832  1.00 26.27  ? 197 TYR C OH  1 
ATOM   9057  N N   . VAL C 1 198 ? 123.920 127.453 80.592  1.00 28.50  ? 198 VAL C N   1 
ATOM   9058  C CA  . VAL C 1 198 ? 124.483 127.764 79.280  1.00 28.50  ? 198 VAL C CA  1 
ATOM   9059  C C   . VAL C 1 198 ? 125.773 128.565 79.419  1.00 28.50  ? 198 VAL C C   1 
ATOM   9060  O O   . VAL C 1 198 ? 126.736 128.352 78.673  1.00 28.50  ? 198 VAL C O   1 
ATOM   9061  C CB  . VAL C 1 198 ? 123.441 128.497 78.416  1.00 28.50  ? 198 VAL C CB  1 
ATOM   9062  C CG1 . VAL C 1 198 ? 124.038 128.892 77.077  1.00 28.50  ? 198 VAL C CG1 1 
ATOM   9063  C CG2 . VAL C 1 198 ? 122.224 127.615 78.218  1.00 28.50  ? 198 VAL C CG2 1 
ATOM   9064  N N   . GLN C 1 199 ? 125.819 129.483 80.380  1.00 29.87  ? 199 GLN C N   1 
ATOM   9065  C CA  . GLN C 1 199 ? 127.007 130.299 80.579  1.00 29.87  ? 199 GLN C CA  1 
ATOM   9066  C C   . GLN C 1 199 ? 128.150 129.465 81.148  1.00 29.87  ? 199 GLN C C   1 
ATOM   9067  O O   . GLN C 1 199 ? 127.942 128.522 81.914  1.00 29.87  ? 199 GLN C O   1 
ATOM   9068  C CB  . GLN C 1 199 ? 126.700 131.471 81.511  1.00 29.87  ? 199 GLN C CB  1 
ATOM   9069  C CG  . GLN C 1 199 ? 125.914 132.595 80.857  1.00 29.87  ? 199 GLN C CG  1 
ATOM   9070  C CD  . GLN C 1 199 ? 124.460 132.236 80.629  1.00 29.87  ? 199 GLN C CD  1 
ATOM   9071  O OE1 . GLN C 1 199 ? 123.692 132.077 81.577  1.00 29.87  ? 199 GLN C OE1 1 
ATOM   9072  N NE2 . GLN C 1 199 ? 124.077 132.099 79.366  1.00 29.87  ? 199 GLN C NE2 1 
ATOM   9073  N N   . ALA C 1 200 ? 129.373 129.828 80.763  1.00 30.61  ? 200 ALA C N   1 
ATOM   9074  C CA  . ALA C 1 200 ? 130.563 129.125 81.223  1.00 30.61  ? 200 ALA C CA  1 
ATOM   9075  C C   . ALA C 1 200 ? 131.025 129.573 82.602  1.00 30.61  ? 200 ALA C C   1 
ATOM   9076  O O   . ALA C 1 200 ? 131.943 128.961 83.157  1.00 30.61  ? 200 ALA C O   1 
ATOM   9077  C CB  . ALA C 1 200 ? 131.704 129.305 80.220  1.00 30.61  ? 200 ALA C CB  1 
ATOM   9078  N N   . SER C 1 201 ? 130.421 130.617 83.165  1.00 29.60  ? 201 SER C N   1 
ATOM   9079  C CA  . SER C 1 201 ? 130.807 131.107 84.485  1.00 29.60  ? 201 SER C CA  1 
ATOM   9080  C C   . SER C 1 201 ? 129.588 131.762 85.118  1.00 29.60  ? 201 SER C C   1 
ATOM   9081  O O   . SER C 1 201 ? 129.165 132.836 84.682  1.00 29.60  ? 201 SER C O   1 
ATOM   9082  C CB  . SER C 1 201 ? 131.971 132.089 84.387  1.00 29.60  ? 201 SER C CB  1 
ATOM   9083  O OG  . SER C 1 201 ? 132.325 132.590 85.663  1.00 29.60  ? 201 SER C OG  1 
ATOM   9084  N N   . GLY C 1 202 ? 129.027 131.115 86.138  1.00 25.83  ? 202 GLY C N   1 
ATOM   9085  C CA  . GLY C 1 202 ? 127.870 131.655 86.816  1.00 25.83  ? 202 GLY C CA  1 
ATOM   9086  C C   . GLY C 1 202 ? 128.233 132.665 87.888  1.00 25.83  ? 202 GLY C C   1 
ATOM   9087  O O   . GLY C 1 202 ? 129.398 132.886 88.213  1.00 25.83  ? 202 GLY C O   1 
ATOM   9088  N N   . ARG C 1 203 ? 127.194 133.283 88.447  1.00 24.66  ? 203 ARG C N   1 
ATOM   9089  C CA  . ARG C 1 203 ? 127.358 134.312 89.466  1.00 24.66  ? 203 ARG C CA  1 
ATOM   9090  C C   . ARG C 1 203 ? 126.035 134.567 90.175  1.00 24.66  ? 203 ARG C C   1 
ATOM   9091  O O   . ARG C 1 203 ? 124.997 134.704 89.522  1.00 24.66  ? 203 ARG C O   1 
ATOM   9092  C CB  . ARG C 1 203 ? 127.885 135.603 88.837  1.00 24.66  ? 203 ARG C CB  1 
ATOM   9093  C CG  . ARG C 1 203 ? 127.891 136.798 89.768  1.00 24.66  ? 203 ARG C CG  1 
ATOM   9094  C CD  . ARG C 1 203 ? 128.021 138.097 88.991  1.00 24.66  ? 203 ARG C CD  1 
ATOM   9095  N NE  . ARG C 1 203 ? 127.036 138.206 87.922  1.00 24.66  ? 203 ARG C NE  1 
ATOM   9096  C CZ  . ARG C 1 203 ? 125.756 138.503 88.106  1.00 24.66  ? 203 ARG C CZ  1 
ATOM   9097  N NH1 . ARG C 1 203 ? 125.264 138.723 89.314  1.00 24.66  ? 203 ARG C NH1 1 
ATOM   9098  N NH2 . ARG C 1 203 ? 124.951 138.584 87.051  1.00 24.66  ? 203 ARG C NH2 1 
ATOM   9099  N N   . VAL C 1 204 ? 126.055 134.633 91.504  1.00 22.23  ? 204 VAL C N   1 
ATOM   9100  C CA  . VAL C 1 204 ? 124.852 134.852 92.301  1.00 22.23  ? 204 VAL C CA  1 
ATOM   9101  C C   . VAL C 1 204 ? 125.076 136.074 93.180  1.00 22.23  ? 204 VAL C C   1 
ATOM   9102  O O   . VAL C 1 204 ? 126.039 136.116 93.954  1.00 22.23  ? 204 VAL C O   1 
ATOM   9103  C CB  . VAL C 1 204 ? 124.496 133.629 93.162  1.00 22.23  ? 204 VAL C CB  1 
ATOM   9104  C CG1 . VAL C 1 204 ? 123.270 133.919 94.010  1.00 22.23  ? 204 VAL C CG1 1 
ATOM   9105  C CG2 . VAL C 1 204 ? 124.263 132.411 92.286  1.00 22.23  ? 204 VAL C CG2 1 
ATOM   9106  N N   . THR C 1 205 ? 124.189 137.060 93.067  1.00 22.47  ? 205 THR C N   1 
ATOM   9107  C CA  . THR C 1 205 ? 124.237 138.270 93.878  1.00 22.47  ? 205 THR C CA  1 
ATOM   9108  C C   . THR C 1 205 ? 122.924 138.409 94.634  1.00 22.47  ? 205 THR C C   1 
ATOM   9109  O O   . THR C 1 205 ? 121.859 138.523 94.017  1.00 22.47  ? 205 THR C O   1 
ATOM   9110  C CB  . THR C 1 205 ? 124.489 139.509 93.013  1.00 22.47  ? 205 THR C CB  1 
ATOM   9111  O OG1 . THR C 1 205 ? 125.573 139.256 92.111  1.00 22.47  ? 205 THR C OG1 1 
ATOM   9112  C CG2 . THR C 1 205 ? 124.831 140.707 93.883  1.00 22.47  ? 205 THR C CG2 1 
ATOM   9113  N N   . VAL C 1 206 ? 122.999 138.401 95.962  1.00 21.14  ? 206 VAL C N   1 
ATOM   9114  C CA  . VAL C 1 206 ? 121.844 138.606 96.830  1.00 21.14  ? 206 VAL C CA  1 
ATOM   9115  C C   . VAL C 1 206 ? 122.167 139.773 97.751  1.00 21.14  ? 206 VAL C C   1 
ATOM   9116  O O   . VAL C 1 206 ? 123.182 139.748 98.458  1.00 21.14  ? 206 VAL C O   1 
ATOM   9117  C CB  . VAL C 1 206 ? 121.500 137.345 97.637  1.00 21.14  ? 206 VAL C CB  1 
ATOM   9118  C CG1 . VAL C 1 206 ? 120.363 137.628 98.601  1.00 21.14  ? 206 VAL C CG1 1 
ATOM   9119  C CG2 . VAL C 1 206 ? 121.138 136.201 96.707  1.00 21.14  ? 206 VAL C CG2 1 
ATOM   9120  N N   . SER C 1 207 ? 121.306 140.789 97.750  1.00 24.05  ? 207 SER C N   1 
ATOM   9121  C CA  . SER C 1 207 ? 121.610 142.022 98.460  1.00 24.05  ? 207 SER C CA  1 
ATOM   9122  C C   . SER C 1 207 ? 120.331 142.675 98.961  1.00 24.05  ? 207 SER C C   1 
ATOM   9123  O O   . SER C 1 207 ? 119.239 142.442 98.437  1.00 24.05  ? 207 SER C O   1 
ATOM   9124  C CB  . SER C 1 207 ? 122.379 142.998 97.563  1.00 24.05  ? 207 SER C CB  1 
ATOM   9125  O OG  . SER C 1 207 ? 121.760 143.112 96.294  1.00 24.05  ? 207 SER C OG  1 
ATOM   9126  N N   . THR C 1 208 ? 120.489 143.500 99.989  1.00 26.65  ? 208 THR C N   1 
ATOM   9127  C CA  . THR C 1 208 ? 119.446 144.366 100.521 1.00 26.65  ? 208 THR C CA  1 
ATOM   9128  C C   . THR C 1 208 ? 119.910 145.818 100.397 1.00 26.65  ? 208 THR C C   1 
ATOM   9129  O O   . THR C 1 208 ? 120.925 146.115 99.761  1.00 26.65  ? 208 THR C O   1 
ATOM   9130  C CB  . THR C 1 208 ? 119.112 144.002 101.971 1.00 26.65  ? 208 THR C CB  1 
ATOM   9131  O OG1 . THR C 1 208 ? 120.238 144.285 102.810 1.00 26.65  ? 208 THR C OG1 1 
ATOM   9132  C CG2 . THR C 1 208 ? 118.757 142.529 102.088 1.00 26.65  ? 208 THR C CG2 1 
ATOM   9133  N N   . ARG C 1 209 ? 119.154 146.731 101.006 1.00 28.69  ? 209 ARG C N   1 
ATOM   9134  C CA  . ARG C 1 209 ? 119.534 148.139 100.981 1.00 28.69  ? 209 ARG C CA  1 
ATOM   9135  C C   . ARG C 1 209 ? 120.733 148.448 101.867 1.00 28.69  ? 209 ARG C C   1 
ATOM   9136  O O   . ARG C 1 209 ? 121.250 149.568 101.805 1.00 28.69  ? 209 ARG C O   1 
ATOM   9137  C CB  . ARG C 1 209 ? 118.355 149.018 101.398 1.00 28.69  ? 209 ARG C CB  1 
ATOM   9138  C CG  . ARG C 1 209 ? 117.229 149.077 100.385 1.00 28.69  ? 209 ARG C CG  1 
ATOM   9139  C CD  . ARG C 1 209 ? 116.613 150.463 100.340 1.00 28.69  ? 209 ARG C CD  1 
ATOM   9140  N NE  . ARG C 1 209 ? 115.290 150.458 99.729  1.00 28.69  ? 209 ARG C NE  1 
ATOM   9141  C CZ  . ARG C 1 209 ? 114.155 150.347 100.404 1.00 28.69  ? 209 ARG C CZ  1 
ATOM   9142  N NH1 . ARG C 1 209 ? 114.143 150.228 101.721 1.00 28.69  ? 209 ARG C NH1 1 
ATOM   9143  N NH2 . ARG C 1 209 ? 113.002 150.360 99.742  1.00 28.69  ? 209 ARG C NH2 1 
ATOM   9144  N N   . ARG C 1 210 ? 121.186 147.498 102.687 1.00 29.25  ? 210 ARG C N   1 
ATOM   9145  C CA  . ARG C 1 210 ? 122.289 147.742 103.603 1.00 29.25  ? 210 ARG C CA  1 
ATOM   9146  C C   . ARG C 1 210 ? 123.388 146.689 103.553 1.00 29.25  ? 210 ARG C C   1 
ATOM   9147  O O   . ARG C 1 210 ? 124.390 146.838 104.261 1.00 29.25  ? 210 ARG C O   1 
ATOM   9148  C CB  . ARG C 1 210 ? 121.768 147.852 105.043 1.00 29.25  ? 210 ARG C CB  1 
ATOM   9149  C CG  . ARG C 1 210 ? 120.671 146.858 105.382 1.00 29.25  ? 210 ARG C CG  1 
ATOM   9150  C CD  . ARG C 1 210 ? 120.439 146.788 106.881 1.00 29.25  ? 210 ARG C CD  1 
ATOM   9151  N NE  . ARG C 1 210 ? 121.547 146.138 107.570 1.00 29.25  ? 210 ARG C NE  1 
ATOM   9152  C CZ  . ARG C 1 210 ? 121.547 144.872 107.963 1.00 29.25  ? 210 ARG C CZ  1 
ATOM   9153  N NH1 . ARG C 1 210 ? 120.504 144.084 107.758 1.00 29.25  ? 210 ARG C NH1 1 
ATOM   9154  N NH2 . ARG C 1 210 ? 122.621 144.384 108.578 1.00 29.25  ? 210 ARG C NH2 1 
ATOM   9155  N N   . SER C 1 211 ? 123.243 145.642 102.746 1.00 27.56  ? 211 SER C N   1 
ATOM   9156  C CA  . SER C 1 211 ? 124.241 144.582 102.691 1.00 27.56  ? 211 SER C CA  1 
ATOM   9157  C C   . SER C 1 211 ? 124.171 143.908 101.328 1.00 27.56  ? 211 SER C C   1 
ATOM   9158  O O   . SER C 1 211 ? 123.204 144.073 100.581 1.00 27.56  ? 211 SER C O   1 
ATOM   9159  C CB  . SER C 1 211 ? 124.038 143.566 103.819 1.00 27.56  ? 211 SER C CB  1 
ATOM   9160  O OG  . SER C 1 211 ? 122.819 142.863 103.658 1.00 27.56  ? 211 SER C OG  1 
ATOM   9161  N N   . GLN C 1 212 ? 125.218 143.147 101.012 1.00 24.84  ? 212 GLN C N   1 
ATOM   9162  C CA  . GLN C 1 212 ? 125.303 142.448 99.738  1.00 24.84  ? 212 GLN C CA  1 
ATOM   9163  C C   . GLN C 1 212 ? 126.202 141.230 99.884  1.00 24.84  ? 212 GLN C C   1 
ATOM   9164  O O   . GLN C 1 212 ? 127.106 141.203 100.723 1.00 24.84  ? 212 GLN C O   1 
ATOM   9165  C CB  . GLN C 1 212 ? 125.838 143.362 98.630  1.00 24.84  ? 212 GLN C CB  1 
ATOM   9166  C CG  . GLN C 1 212 ? 127.267 143.826 98.853  1.00 24.84  ? 212 GLN C CG  1 
ATOM   9167  C CD  . GLN C 1 212 ? 127.797 144.655 97.703  1.00 24.84  ? 212 GLN C CD  1 
ATOM   9168  O OE1 . GLN C 1 212 ? 127.124 144.832 96.690  1.00 24.84  ? 212 GLN C OE1 1 
ATOM   9169  N NE2 . GLN C 1 212 ? 129.010 145.169 97.855  1.00 24.84  ? 212 GLN C NE2 1 
ATOM   9170  N N   . GLN C 1 213 ? 125.943 140.219 99.055  1.00 22.07  ? 213 GLN C N   1 
ATOM   9171  C CA  . GLN C 1 213 ? 126.769 139.020 98.982  1.00 22.07  ? 213 GLN C CA  1 
ATOM   9172  C C   . GLN C 1 213 ? 126.818 138.540 97.541  1.00 22.07  ? 213 GLN C C   1 
ATOM   9173  O O   . GLN C 1 213 ? 125.772 138.348 96.916  1.00 22.07  ? 213 GLN C O   1 
ATOM   9174  C CB  . GLN C 1 213 ? 126.230 137.898 99.879  1.00 22.07  ? 213 GLN C CB  1 
ATOM   9175  C CG  . GLN C 1 213 ? 126.288 138.180 101.367 1.00 22.07  ? 213 GLN C CG  1 
ATOM   9176  C CD  . GLN C 1 213 ? 125.373 137.274 102.163 1.00 22.07  ? 213 GLN C CD  1 
ATOM   9177  O OE1 . GLN C 1 213 ? 124.219 137.611 102.420 1.00 22.07  ? 213 GLN C OE1 1 
ATOM   9178  N NE2 . GLN C 1 213 ? 125.885 136.117 102.559 1.00 22.07  ? 213 GLN C NE2 1 
ATOM   9179  N N   . THR C 1 214 ? 128.027 138.344 97.020  1.00 24.28  ? 214 THR C N   1 
ATOM   9180  C CA  . THR C 1 214 ? 128.226 137.812 95.678  1.00 24.28  ? 214 THR C CA  1 
ATOM   9181  C C   . THR C 1 214 ? 129.126 136.591 95.763  1.00 24.28  ? 214 THR C C   1 
ATOM   9182  O O   . THR C 1 214 ? 130.185 136.640 96.396  1.00 24.28  ? 214 THR C O   1 
ATOM   9183  C CB  . THR C 1 214 ? 128.838 138.859 94.742  1.00 24.28  ? 214 THR C CB  1 
ATOM   9184  O OG1 . THR C 1 214 ? 127.965 139.991 94.652  1.00 24.28  ? 214 THR C OG1 1 
ATOM   9185  C CG2 . THR C 1 214 ? 129.040 138.278 93.351  1.00 24.28  ? 214 THR C CG2 1 
ATOM   9186  N N   . ILE C 1 215 ? 128.706 135.501 95.124  1.00 22.18  ? 215 ILE C N   1 
ATOM   9187  C CA  . ILE C 1 215 ? 129.409 134.226 95.179  1.00 22.18  ? 215 ILE C CA  1 
ATOM   9188  C C   . ILE C 1 215 ? 129.688 133.766 93.756  1.00 22.18  ? 215 ILE C C   1 
ATOM   9189  O O   . ILE C 1 215 ? 128.788 133.777 92.910  1.00 22.18  ? 215 ILE C O   1 
ATOM   9190  C CB  . ILE C 1 215 ? 128.597 133.158 95.938  1.00 22.18  ? 215 ILE C CB  1 
ATOM   9191  C CG1 . ILE C 1 215 ? 128.151 133.685 97.304  1.00 22.18  ? 215 ILE C CG1 1 
ATOM   9192  C CG2 . ILE C 1 215 ? 129.412 131.886 96.100  1.00 22.18  ? 215 ILE C CG2 1 
ATOM   9193  C CD1 . ILE C 1 215 ? 129.288 134.048 98.226  1.00 22.18  ? 215 ILE C CD1 1 
ATOM   9194  N N   . VAL C 1 216 ? 130.924 133.366 93.495  1.00 23.10  ? 216 VAL C N   1 
ATOM   9195  C CA  . VAL C 1 216 ? 131.338 132.813 92.209  1.00 23.10  ? 216 VAL C CA  1 
ATOM   9196  C C   . VAL C 1 216 ? 131.569 131.317 92.397  1.00 23.10  ? 216 VAL C C   1 
ATOM   9197  O O   . VAL C 1 216 ? 132.358 130.926 93.268  1.00 23.10  ? 216 VAL C O   1 
ATOM   9198  C CB  . VAL C 1 216 ? 132.599 133.503 91.668  1.00 23.10  ? 216 VAL C CB  1 
ATOM   9199  C CG1 . VAL C 1 216 ? 132.993 132.909 90.327  1.00 23.10  ? 216 VAL C CG1 1 
ATOM   9200  C CG2 . VAL C 1 216 ? 132.369 134.998 91.540  1.00 23.10  ? 216 VAL C CG2 1 
ATOM   9201  N N   . PRO C 1 217 ? 130.907 130.455 91.629  1.00 23.13  ? 217 PRO C N   1 
ATOM   9202  C CA  . PRO C 1 217 ? 131.076 129.011 91.824  1.00 23.13  ? 217 PRO C CA  1 
ATOM   9203  C C   . PRO C 1 217 ? 132.477 128.538 91.470  1.00 23.13  ? 217 PRO C C   1 
ATOM   9204  O O   . PRO C 1 217 ? 133.179 129.139 90.654  1.00 23.13  ? 217 PRO C O   1 
ATOM   9205  C CB  . PRO C 1 217 ? 130.033 128.401 90.880  1.00 23.13  ? 217 PRO C CB  1 
ATOM   9206  C CG  . PRO C 1 217 ? 129.744 129.468 89.884  1.00 23.13  ? 217 PRO C CG  1 
ATOM   9207  C CD  . PRO C 1 217 ? 129.894 130.764 90.609  1.00 23.13  ? 217 PRO C CD  1 
ATOM   9208  N N   . ASN C 1 218 ? 132.875 127.437 92.101  1.00 26.02  ? 218 ASN C N   1 
ATOM   9209  C CA  . ASN C 1 218 ? 134.179 126.822 91.895  1.00 26.02  ? 218 ASN C CA  1 
ATOM   9210  C C   . ASN C 1 218 ? 134.001 125.469 91.221  1.00 26.02  ? 218 ASN C C   1 
ATOM   9211  O O   . ASN C 1 218 ? 133.232 124.630 91.700  1.00 26.02  ? 218 ASN C O   1 
ATOM   9212  C CB  . ASN C 1 218 ? 134.918 126.651 93.222  1.00 26.02  ? 218 ASN C CB  1 
ATOM   9213  C CG  . ASN C 1 218 ? 134.764 127.849 94.136  1.00 26.02  ? 218 ASN C CG  1 
ATOM   9214  O OD1 . ASN C 1 218 ? 134.296 127.724 95.267  1.00 26.02  ? 218 ASN C OD1 1 
ATOM   9215  N ND2 . ASN C 1 218 ? 135.162 129.019 93.651  1.00 26.02  ? 218 ASN C ND2 1 
ATOM   9216  N N   . ILE C 1 219 ? 134.719 125.254 90.123  1.00 26.47  ? 219 ILE C N   1 
ATOM   9217  C CA  . ILE C 1 219 ? 134.639 124.022 89.348  1.00 26.47  ? 219 ILE C CA  1 
ATOM   9218  C C   . ILE C 1 219 ? 135.830 123.147 89.712  1.00 26.47  ? 219 ILE C C   1 
ATOM   9219  O O   . ILE C 1 219 ? 136.970 123.623 89.746  1.00 26.47  ? 219 ILE C O   1 
ATOM   9220  C CB  . ILE C 1 219 ? 134.604 124.310 87.837  1.00 26.47  ? 219 ILE C CB  1 
ATOM   9221  C CG1 . ILE C 1 219 ? 133.268 124.941 87.446  1.00 26.47  ? 219 ILE C CG1 1 
ATOM   9222  C CG2 . ILE C 1 219 ? 134.838 123.039 87.042  1.00 26.47  ? 219 ILE C CG2 1 
ATOM   9223  C CD1 . ILE C 1 219 ? 133.317 125.717 86.153  1.00 26.47  ? 219 ILE C CD1 1 
ATOM   9224  N N   . GLY C 1 220 ? 135.565 121.873 89.992  1.00 25.39  ? 220 GLY C N   1 
ATOM   9225  C CA  . GLY C 1 220 ? 136.618 120.942 90.342  1.00 25.39  ? 220 GLY C CA  1 
ATOM   9226  C C   . GLY C 1 220 ? 136.093 119.650 90.930  1.00 25.39  ? 220 GLY C C   1 
ATOM   9227  O O   . GLY C 1 220 ? 135.024 119.631 91.545  1.00 25.39  ? 220 GLY C O   1 
ATOM   9228  N N   . SER C 1 221 ? 136.837 118.562 90.749  1.00 25.10  ? 221 SER C N   1 
ATOM   9229  C CA  . SER C 1 221 ? 136.404 117.266 91.251  1.00 25.10  ? 221 SER C CA  1 
ATOM   9230  C C   . SER C 1 221 ? 136.564 117.185 92.764  1.00 25.10  ? 221 SER C C   1 
ATOM   9231  O O   . SER C 1 221 ? 137.450 117.806 93.356  1.00 25.10  ? 221 SER C O   1 
ATOM   9232  C CB  . SER C 1 221 ? 137.192 116.142 90.582  1.00 25.10  ? 221 SER C CB  1 
ATOM   9233  O OG  . SER C 1 221 ? 136.848 116.024 89.213  1.00 25.10  ? 221 SER C OG  1 
ATOM   9234  N N   . ARG C 1 222 ? 135.693 116.403 93.384  1.00 23.21  ? 222 ARG C N   1 
ATOM   9235  C CA  . ARG C 1 222 ? 135.649 116.212 94.824  1.00 23.21  ? 222 ARG C CA  1 
ATOM   9236  C C   . ARG C 1 222 ? 135.391 114.741 95.102  1.00 23.21  ? 222 ARG C C   1 
ATOM   9237  O O   . ARG C 1 222 ? 134.951 114.005 94.212  1.00 23.21  ? 222 ARG C O   1 
ATOM   9238  C CB  . ARG C 1 222 ? 134.558 117.081 95.464  1.00 23.21  ? 222 ARG C CB  1 
ATOM   9239  C CG  . ARG C 1 222 ? 134.936 118.542 95.612  1.00 23.21  ? 222 ARG C CG  1 
ATOM   9240  C CD  . ARG C 1 222 ? 133.762 119.440 95.283  1.00 23.21  ? 222 ARG C CD  1 
ATOM   9241  N NE  . ARG C 1 222 ? 134.154 120.834 95.122  1.00 23.21  ? 222 ARG C NE  1 
ATOM   9242  C CZ  . ARG C 1 222 ? 133.916 121.558 94.038  1.00 23.21  ? 222 ARG C CZ  1 
ATOM   9243  N NH1 . ARG C 1 222 ? 133.303 121.042 92.986  1.00 23.21  ? 222 ARG C NH1 1 
ATOM   9244  N NH2 . ARG C 1 222 ? 134.300 122.830 94.009  1.00 23.21  ? 222 ARG C NH2 1 
ATOM   9245  N N   . PRO C 1 223 ? 135.679 114.273 96.318  1.00 25.39  ? 223 PRO C N   1 
ATOM   9246  C CA  . PRO C 1 223 ? 135.378 112.876 96.652  1.00 25.39  ? 223 PRO C CA  1 
ATOM   9247  C C   . PRO C 1 223 ? 133.892 112.576 96.520  1.00 25.39  ? 223 PRO C C   1 
ATOM   9248  O O   . PRO C 1 223 ? 133.037 113.420 96.794  1.00 25.39  ? 223 PRO C O   1 
ATOM   9249  C CB  . PRO C 1 223 ? 135.847 112.746 98.105  1.00 25.39  ? 223 PRO C CB  1 
ATOM   9250  C CG  . PRO C 1 223 ? 136.849 113.821 98.280  1.00 25.39  ? 223 PRO C CG  1 
ATOM   9251  C CD  . PRO C 1 223 ? 136.418 114.950 97.398  1.00 25.39  ? 223 PRO C CD  1 
ATOM   9252  N N   . TRP C 1 224 ? 133.593 111.353 96.089  1.00 27.29  ? 224 TRP C N   1 
ATOM   9253  C CA  . TRP C 1 224 ? 132.210 110.943 95.887  1.00 27.29  ? 224 TRP C CA  1 
ATOM   9254  C C   . TRP C 1 224 ? 131.481 110.831 97.218  1.00 27.29  ? 224 TRP C C   1 
ATOM   9255  O O   . TRP C 1 224 ? 131.968 110.194 98.157  1.00 27.29  ? 224 TRP C O   1 
ATOM   9256  C CB  . TRP C 1 224 ? 132.156 109.606 95.151  1.00 27.29  ? 224 TRP C CB  1 
ATOM   9257  C CG  . TRP C 1 224 ? 132.064 109.730 93.666  1.00 27.29  ? 224 TRP C CG  1 
ATOM   9258  C CD1 . TRP C 1 224 ? 132.645 110.683 92.885  1.00 27.29  ? 224 TRP C CD1 1 
ATOM   9259  C CD2 . TRP C 1 224 ? 131.346 108.866 92.780  1.00 27.29  ? 224 TRP C CD2 1 
ATOM   9260  N NE1 . TRP C 1 224 ? 132.333 110.467 91.565  1.00 27.29  ? 224 TRP C NE1 1 
ATOM   9261  C CE2 . TRP C 1 224 ? 131.536 109.357 91.474  1.00 27.29  ? 224 TRP C CE2 1 
ATOM   9262  C CE3 . TRP C 1 224 ? 130.560 107.725 92.963  1.00 27.29  ? 224 TRP C CE3 1 
ATOM   9263  C CZ2 . TRP C 1 224 ? 130.969 108.747 90.358  1.00 27.29  ? 224 TRP C CZ2 1 
ATOM   9264  C CZ3 . TRP C 1 224 ? 129.998 107.122 91.855  1.00 27.29  ? 224 TRP C CZ3 1 
ATOM   9265  C CH2 . TRP C 1 224 ? 130.206 107.633 90.569  1.00 27.29  ? 224 TRP C CH2 1 
ATOM   9266  N N   . VAL C 1 225 ? 130.306 111.450 97.296  1.00 24.87  ? 225 VAL C N   1 
ATOM   9267  C CA  . VAL C 1 225 ? 129.415 111.334 98.444  1.00 24.87  ? 225 VAL C CA  1 
ATOM   9268  C C   . VAL C 1 225 ? 128.033 111.018 97.895  1.00 24.87  ? 225 VAL C C   1 
ATOM   9269  O O   . VAL C 1 225 ? 127.386 111.887 97.297  1.00 24.87  ? 225 VAL C O   1 
ATOM   9270  C CB  . VAL C 1 225 ? 129.388 112.606 99.301  1.00 24.87  ? 225 VAL C CB  1 
ATOM   9271  C CG1 . VAL C 1 225 ? 128.328 112.490 100.379 1.00 24.87  ? 225 VAL C CG1 1 
ATOM   9272  C CG2 . VAL C 1 225 ? 130.750 112.858 99.922  1.00 24.87  ? 225 VAL C CG2 1 
ATOM   9273  N N   . ARG C 1 226 ? 127.582 109.778 98.091  1.00 24.71  ? 226 ARG C N   1 
ATOM   9274  C CA  . ARG C 1 226 ? 126.306 109.301 97.556  1.00 24.71  ? 226 ARG C CA  1 
ATOM   9275  C C   . ARG C 1 226 ? 126.248 109.458 96.037  1.00 24.71  ? 226 ARG C C   1 
ATOM   9276  O O   . ARG C 1 226 ? 125.197 109.748 95.463  1.00 24.71  ? 226 ARG C O   1 
ATOM   9277  C CB  . ARG C 1 226 ? 125.123 110.001 98.228  1.00 24.71  ? 226 ARG C CB  1 
ATOM   9278  C CG  . ARG C 1 226 ? 124.957 109.648 99.698  1.00 24.71  ? 226 ARG C CG  1 
ATOM   9279  C CD  . ARG C 1 226 ? 123.775 110.370 100.323 1.00 24.71  ? 226 ARG C CD  1 
ATOM   9280  N NE  . ARG C 1 226 ? 124.091 111.749 100.676 1.00 24.71  ? 226 ARG C NE  1 
ATOM   9281  C CZ  . ARG C 1 226 ? 124.794 112.110 101.740 1.00 24.71  ? 226 ARG C CZ  1 
ATOM   9282  N NH1 . ARG C 1 226 ? 125.281 111.215 102.583 1.00 24.71  ? 226 ARG C NH1 1 
ATOM   9283  N NH2 . ARG C 1 226 ? 125.010 113.402 101.967 1.00 24.71  ? 226 ARG C NH2 1 
ATOM   9284  N N   . GLY C 1 227 ? 127.389 109.259 95.381  1.00 26.04  ? 227 GLY C N   1 
ATOM   9285  C CA  . GLY C 1 227 ? 127.460 109.262 93.936  1.00 26.04  ? 227 GLY C CA  1 
ATOM   9286  C C   . GLY C 1 227 ? 127.712 110.604 93.287  1.00 26.04  ? 227 GLY C C   1 
ATOM   9287  O O   . GLY C 1 227 ? 127.765 110.672 92.053  1.00 26.04  ? 227 GLY C O   1 
ATOM   9288  N N   . GLN C 1 228 ? 127.874 111.671 94.065  1.00 25.30  ? 228 GLN C N   1 
ATOM   9289  C CA  . GLN C 1 228 ? 128.032 113.017 93.532  1.00 25.30  ? 228 GLN C CA  1 
ATOM   9290  C C   . GLN C 1 228 ? 129.405 113.559 93.895  1.00 25.30  ? 228 GLN C C   1 
ATOM   9291  O O   . GLN C 1 228 ? 129.824 113.475 95.054  1.00 25.30  ? 228 GLN C O   1 
ATOM   9292  C CB  . GLN C 1 228 ? 126.944 113.953 94.067  1.00 25.30  ? 228 GLN C CB  1 
ATOM   9293  C CG  . GLN C 1 228 ? 125.542 113.370 94.044  1.00 25.30  ? 228 GLN C CG  1 
ATOM   9294  C CD  . GLN C 1 228 ? 125.056 113.066 92.642  1.00 25.30  ? 228 GLN C CD  1 
ATOM   9295  O OE1 . GLN C 1 228 ? 125.311 113.823 91.707  1.00 25.30  ? 228 GLN C OE1 1 
ATOM   9296  N NE2 . GLN C 1 228 ? 124.347 111.956 92.491  1.00 25.30  ? 228 GLN C NE2 1 
ATOM   9297  N N   . SER C 1 229 ? 130.100 114.115 92.905  1.00 23.82  ? 229 SER C N   1 
ATOM   9298  C CA  . SER C 1 229 ? 131.352 114.823 93.126  1.00 23.82  ? 229 SER C CA  1 
ATOM   9299  C C   . SER C 1 229 ? 131.171 116.335 93.175  1.00 23.82  ? 229 SER C C   1 
ATOM   9300  O O   . SER C 1 229 ? 132.160 117.060 93.306  1.00 23.82  ? 229 SER C O   1 
ATOM   9301  C CB  . SER C 1 229 ? 132.367 114.458 92.040  1.00 23.82  ? 229 SER C CB  1 
ATOM   9302  O OG  . SER C 1 229 ? 131.821 114.649 90.748  1.00 23.82  ? 229 SER C OG  1 
ATOM   9303  N N   . SER C 1 230 ? 129.939 116.822 93.069  1.00 22.96  ? 230 SER C N   1 
ATOM   9304  C CA  . SER C 1 230 ? 129.628 118.238 93.170  1.00 22.96  ? 230 SER C CA  1 
ATOM   9305  C C   . SER C 1 230 ? 129.089 118.559 94.559  1.00 22.96  ? 230 SER C C   1 
ATOM   9306  O O   . SER C 1 230 ? 128.610 117.684 95.282  1.00 22.96  ? 230 SER C O   1 
ATOM   9307  C CB  . SER C 1 230 ? 128.608 118.646 92.105  1.00 22.96  ? 230 SER C CB  1 
ATOM   9308  O OG  . SER C 1 230 ? 129.116 118.426 90.802  1.00 22.96  ? 230 SER C OG  1 
ATOM   9309  N N   . ARG C 1 231 ? 129.168 119.836 94.924  1.00 21.27  ? 231 ARG C N   1 
ATOM   9310  C CA  . ARG C 1 231 ? 128.737 120.297 96.234  1.00 21.27  ? 231 ARG C CA  1 
ATOM   9311  C C   . ARG C 1 231 ? 127.820 121.503 96.082  1.00 21.27  ? 231 ARG C C   1 
ATOM   9312  O O   . ARG C 1 231 ? 127.639 122.046 94.991  1.00 21.27  ? 231 ARG C O   1 
ATOM   9313  C CB  . ARG C 1 231 ? 129.932 120.657 97.127  1.00 21.27  ? 231 ARG C CB  1 
ATOM   9314  C CG  . ARG C 1 231 ? 130.900 119.517 97.362  1.00 21.27  ? 231 ARG C CG  1 
ATOM   9315  C CD  . ARG C 1 231 ? 130.293 118.414 98.203  1.00 21.27  ? 231 ARG C CD  1 
ATOM   9316  N NE  . ARG C 1 231 ? 131.306 117.462 98.641  1.00 21.27  ? 231 ARG C NE  1 
ATOM   9317  C CZ  . ARG C 1 231 ? 131.595 116.331 98.013  1.00 21.27  ? 231 ARG C CZ  1 
ATOM   9318  N NH1 . ARG C 1 231 ? 130.957 115.968 96.913  1.00 21.27  ? 231 ARG C NH1 1 
ATOM   9319  N NH2 . ARG C 1 231 ? 132.551 115.546 98.500  1.00 21.27  ? 231 ARG C NH2 1 
ATOM   9320  N N   . ILE C 1 232 ? 127.232 121.911 97.204  1.00 18.88  ? 232 ILE C N   1 
ATOM   9321  C CA  . ILE C 1 232 ? 126.377 123.090 97.275  1.00 18.88  ? 232 ILE C CA  1 
ATOM   9322  C C   . ILE C 1 232 ? 126.721 123.845 98.551  1.00 18.88  ? 232 ILE C C   1 
ATOM   9323  O O   . ILE C 1 232 ? 126.782 123.250 99.630  1.00 18.88  ? 232 ILE C O   1 
ATOM   9324  C CB  . ILE C 1 232 ? 124.882 122.713 97.246  1.00 18.88  ? 232 ILE C CB  1 
ATOM   9325  C CG1 . ILE C 1 232 ? 124.435 122.408 95.816  1.00 18.88  ? 232 ILE C CG1 1 
ATOM   9326  C CG2 . ILE C 1 232 ? 124.031 123.825 97.833  1.00 18.88  ? 232 ILE C CG2 1 
ATOM   9327  C CD1 . ILE C 1 232 ? 123.137 121.644 95.732  1.00 18.88  ? 232 ILE C CD1 1 
ATOM   9328  N N   . SER C 1 233 ? 126.952 125.149 98.432  1.00 18.34  ? 233 SER C N   1 
ATOM   9329  C CA  . SER C 1 233 ? 127.231 125.997 99.582  1.00 18.34  ? 233 SER C CA  1 
ATOM   9330  C C   . SER C 1 233 ? 125.951 126.690 100.026 1.00 18.34  ? 233 SER C C   1 
ATOM   9331  O O   . SER C 1 233 ? 125.096 127.016 99.200  1.00 18.34  ? 233 SER C O   1 
ATOM   9332  C CB  . SER C 1 233 ? 128.305 127.034 99.254  1.00 18.34  ? 233 SER C CB  1 
ATOM   9333  O OG  . SER C 1 233 ? 129.583 126.431 99.164  1.00 18.34  ? 233 SER C OG  1 
ATOM   9334  N N   . ILE C 1 234 ? 125.822 126.912 101.331 1.00 17.01  ? 234 ILE C N   1 
ATOM   9335  C CA  . ILE C 1 234 ? 124.599 127.435 101.930 1.00 17.01  ? 234 ILE C CA  1 
ATOM   9336  C C   . ILE C 1 234 ? 124.888 128.802 102.532 1.00 17.01  ? 234 ILE C C   1 
ATOM   9337  O O   . ILE C 1 234 ? 125.846 128.962 103.298 1.00 17.01  ? 234 ILE C O   1 
ATOM   9338  C CB  . ILE C 1 234 ? 124.039 126.471 102.991 1.00 17.01  ? 234 ILE C CB  1 
ATOM   9339  C CG1 . ILE C 1 234 ? 123.628 125.147 102.342 1.00 17.01  ? 234 ILE C CG1 1 
ATOM   9340  C CG2 . ILE C 1 234 ? 122.862 127.097 103.719 1.00 17.01  ? 234 ILE C CG2 1 
ATOM   9341  C CD1 . ILE C 1 234 ? 122.514 125.283 101.333 1.00 17.01  ? 234 ILE C CD1 1 
ATOM   9342  N N   . TYR C 1 235 ? 124.058 129.785 102.185 1.00 17.36  ? 235 TYR C N   1 
ATOM   9343  C CA  . TYR C 1 235 ? 124.169 131.143 102.695 1.00 17.36  ? 235 TYR C CA  1 
ATOM   9344  C C   . TYR C 1 235 ? 122.807 131.606 103.193 1.00 17.36  ? 235 TYR C C   1 
ATOM   9345  O O   . TYR C 1 235 ? 121.775 131.009 102.880 1.00 17.36  ? 235 TYR C O   1 
ATOM   9346  C CB  . TYR C 1 235 ? 124.696 132.107 101.624 1.00 17.36  ? 235 TYR C CB  1 
ATOM   9347  C CG  . TYR C 1 235 ? 126.018 131.684 101.030 1.00 17.36  ? 235 TYR C CG  1 
ATOM   9348  C CD1 . TYR C 1 235 ? 127.215 132.061 101.617 1.00 17.36  ? 235 TYR C CD1 1 
ATOM   9349  C CD2 . TYR C 1 235 ? 126.068 130.899 99.887  1.00 17.36  ? 235 TYR C CD2 1 
ATOM   9350  C CE1 . TYR C 1 235 ? 128.424 131.673 101.082 1.00 17.36  ? 235 TYR C CE1 1 
ATOM   9351  C CE2 . TYR C 1 235 ? 127.272 130.506 99.346  1.00 17.36  ? 235 TYR C CE2 1 
ATOM   9352  C CZ  . TYR C 1 235 ? 128.446 130.896 99.948  1.00 17.36  ? 235 TYR C CZ  1 
ATOM   9353  O OH  . TYR C 1 235 ? 129.651 130.508 99.412  1.00 17.36  ? 235 TYR C OH  1 
ATOM   9354  N N   . TRP C 1 236 ? 122.812 132.680 103.981 1.00 18.86  ? 236 TRP C N   1 
ATOM   9355  C CA  . TRP C 1 236 ? 121.582 133.210 104.550 1.00 18.86  ? 236 TRP C CA  1 
ATOM   9356  C C   . TRP C 1 236 ? 121.616 134.732 104.551 1.00 18.86  ? 236 TRP C C   1 
ATOM   9357  O O   . TRP C 1 236 ? 122.685 135.346 104.549 1.00 18.86  ? 236 TRP C O   1 
ATOM   9358  C CB  . TRP C 1 236 ? 121.341 132.677 105.973 1.00 18.86  ? 236 TRP C CB  1 
ATOM   9359  C CG  . TRP C 1 236 ? 122.209 133.286 107.036 1.00 18.86  ? 236 TRP C CG  1 
ATOM   9360  C CD1 . TRP C 1 236 ? 121.945 134.404 107.769 1.00 18.86  ? 236 TRP C CD1 1 
ATOM   9361  C CD2 . TRP C 1 236 ? 123.472 132.793 107.496 1.00 18.86  ? 236 TRP C CD2 1 
ATOM   9362  N NE1 . TRP C 1 236 ? 122.970 134.645 108.650 1.00 18.86  ? 236 TRP C NE1 1 
ATOM   9363  C CE2 . TRP C 1 236 ? 123.920 133.669 108.502 1.00 18.86  ? 236 TRP C CE2 1 
ATOM   9364  C CE3 . TRP C 1 236 ? 124.270 131.700 107.150 1.00 18.86  ? 236 TRP C CE3 1 
ATOM   9365  C CZ2 . TRP C 1 236 ? 125.128 133.486 109.167 1.00 18.86  ? 236 TRP C CZ2 1 
ATOM   9366  C CZ3 . TRP C 1 236 ? 125.469 131.520 107.811 1.00 18.86  ? 236 TRP C CZ3 1 
ATOM   9367  C CH2 . TRP C 1 236 ? 125.887 132.408 108.808 1.00 18.86  ? 236 TRP C CH2 1 
ATOM   9368  N N   . THR C 1 237 ? 120.425 135.330 104.549 1.00 19.78  ? 237 THR C N   1 
ATOM   9369  C CA  . THR C 1 237 ? 120.254 136.775 104.537 1.00 19.78  ? 237 THR C CA  1 
ATOM   9370  C C   . THR C 1 237 ? 119.056 137.140 105.400 1.00 19.78  ? 237 THR C C   1 
ATOM   9371  O O   . THR C 1 237 ? 118.042 136.437 105.392 1.00 19.78  ? 237 THR C O   1 
ATOM   9372  C CB  . THR C 1 237 ? 120.052 137.303 103.109 1.00 19.78  ? 237 THR C CB  1 
ATOM   9373  O OG1 . THR C 1 237 ? 121.103 136.816 102.266 1.00 19.78  ? 237 THR C OG1 1 
ATOM   9374  C CG2 . THR C 1 237 ? 120.063 138.821 103.085 1.00 19.78  ? 237 THR C CG2 1 
ATOM   9375  N N   . ILE C 1 238 ? 119.173 138.238 106.142 1.00 23.51  ? 238 ILE C N   1 
ATOM   9376  C CA  . ILE C 1 238 ? 118.116 138.722 107.023 1.00 23.51  ? 238 ILE C CA  1 
ATOM   9377  C C   . ILE C 1 238 ? 117.606 140.051 106.484 1.00 23.51  ? 238 ILE C C   1 
ATOM   9378  O O   . ILE C 1 238 ? 118.395 140.967 106.225 1.00 23.51  ? 238 ILE C O   1 
ATOM   9379  C CB  . ILE C 1 238 ? 118.610 138.865 108.472 1.00 23.51  ? 238 ILE C CB  1 
ATOM   9380  C CG1 . ILE C 1 238 ? 118.941 137.492 109.054 1.00 23.51  ? 238 ILE C CG1 1 
ATOM   9381  C CG2 . ILE C 1 238 ? 117.564 139.560 109.326 1.00 23.51  ? 238 ILE C CG2 1 
ATOM   9382  C CD1 . ILE C 1 238 ? 119.697 137.547 110.351 1.00 23.51  ? 238 ILE C CD1 1 
ATOM   9383  N N   . VAL C 1 239 ? 116.290 140.156 106.320 1.00 24.42  ? 239 VAL C N   1 
ATOM   9384  C CA  . VAL C 1 239 ? 115.645 141.347 105.779 1.00 24.42  ? 239 VAL C CA  1 
ATOM   9385  C C   . VAL C 1 239 ? 114.829 141.995 106.889 1.00 24.42  ? 239 VAL C C   1 
ATOM   9386  O O   . VAL C 1 239 ? 113.849 141.414 107.371 1.00 24.42  ? 239 VAL C O   1 
ATOM   9387  C CB  . VAL C 1 239 ? 114.761 141.011 104.568 1.00 24.42  ? 239 VAL C CB  1 
ATOM   9388  C CG1 . VAL C 1 239 ? 114.195 142.277 103.957 1.00 24.42  ? 239 VAL C CG1 1 
ATOM   9389  C CG2 . VAL C 1 239 ? 115.556 140.231 103.537 1.00 24.42  ? 239 VAL C CG2 1 
ATOM   9390  N N   . LYS C 1 240 ? 115.233 143.196 107.291 1.00 27.91  ? 240 LYS C N   1 
ATOM   9391  C CA  . LYS C 1 240 ? 114.545 143.949 108.325 1.00 27.91  ? 240 LYS C CA  1 
ATOM   9392  C C   . LYS C 1 240 ? 113.224 144.498 107.794 1.00 27.91  ? 240 LYS C C   1 
ATOM   9393  O O   . LYS C 1 240 ? 113.047 144.643 106.582 1.00 27.91  ? 240 LYS C O   1 
ATOM   9394  C CB  . LYS C 1 240 ? 115.434 145.088 108.814 1.00 27.91  ? 240 LYS C CB  1 
ATOM   9395  C CG  . LYS C 1 240 ? 116.743 144.628 109.434 1.00 27.91  ? 240 LYS C CG  1 
ATOM   9396  C CD  . LYS C 1 240 ? 116.507 143.771 110.665 1.00 27.91  ? 240 LYS C CD  1 
ATOM   9397  C CE  . LYS C 1 240 ? 115.897 144.584 111.792 1.00 27.91  ? 240 LYS C CE  1 
ATOM   9398  N NZ  . LYS C 1 240 ? 116.826 145.643 112.274 1.00 27.91  ? 240 LYS C NZ  1 
ATOM   9399  N N   . PRO C 1 241 ? 112.269 144.793 108.678 1.00 28.00  ? 241 PRO C N   1 
ATOM   9400  C CA  . PRO C 1 241 ? 110.992 145.351 108.216 1.00 28.00  ? 241 PRO C CA  1 
ATOM   9401  C C   . PRO C 1 241 ? 111.195 146.658 107.463 1.00 28.00  ? 241 PRO C C   1 
ATOM   9402  O O   . PRO C 1 241 ? 111.968 147.523 107.876 1.00 28.00  ? 241 PRO C O   1 
ATOM   9403  C CB  . PRO C 1 241 ? 110.207 145.564 109.514 1.00 28.00  ? 241 PRO C CB  1 
ATOM   9404  C CG  . PRO C 1 241 ? 110.809 144.612 110.480 1.00 28.00  ? 241 PRO C CG  1 
ATOM   9405  C CD  . PRO C 1 241 ? 112.262 144.534 110.128 1.00 28.00  ? 241 PRO C CD  1 
ATOM   9406  N N   . GLY C 1 242 ? 110.480 146.795 106.349 1.00 27.66  ? 242 GLY C N   1 
ATOM   9407  C CA  . GLY C 1 242 ? 110.626 147.944 105.484 1.00 27.66  ? 242 GLY C CA  1 
ATOM   9408  C C   . GLY C 1 242 ? 111.757 147.860 104.482 1.00 27.66  ? 242 GLY C C   1 
ATOM   9409  O O   . GLY C 1 242 ? 111.955 148.813 103.719 1.00 27.66  ? 242 GLY C O   1 
ATOM   9410  N N   . ASP C 1 243 ? 112.503 146.759 104.456 1.00 28.37  ? 243 ASP C N   1 
ATOM   9411  C CA  . ASP C 1 243 ? 113.616 146.595 103.534 1.00 28.37  ? 243 ASP C CA  1 
ATOM   9412  C C   . ASP C 1 243 ? 113.160 145.800 102.310 1.00 28.37  ? 243 ASP C C   1 
ATOM   9413  O O   . ASP C 1 243 ? 112.012 145.359 102.218 1.00 28.37  ? 243 ASP C O   1 
ATOM   9414  C CB  . ASP C 1 243 ? 114.791 145.924 104.242 1.00 28.37  ? 243 ASP C CB  1 
ATOM   9415  C CG  . ASP C 1 243 ? 116.132 146.394 103.719 1.00 28.37  ? 243 ASP C CG  1 
ATOM   9416  O OD1 . ASP C 1 243 ? 116.224 146.713 102.517 1.00 28.37  ? 243 ASP C OD1 1 
ATOM   9417  O OD2 . ASP C 1 243 ? 117.096 146.438 104.511 1.00 28.37  ? 243 ASP C OD2 1 
ATOM   9418  N N   . VAL C 1 244 ? 114.065 145.612 101.349 1.00 27.28  ? 244 VAL C N   1 
ATOM   9419  C CA  . VAL C 1 244 ? 113.771 144.896 100.114 1.00 27.28  ? 244 VAL C CA  1 
ATOM   9420  C C   . VAL C 1 244 ? 114.862 143.859 99.883  1.00 27.28  ? 244 VAL C C   1 
ATOM   9421  O O   . VAL C 1 244 ? 116.005 144.025 100.319 1.00 27.28  ? 244 VAL C O   1 
ATOM   9422  C CB  . VAL C 1 244 ? 113.664 145.855 98.901  1.00 27.28  ? 244 VAL C CB  1 
ATOM   9423  C CG1 . VAL C 1 244 ? 113.028 145.159 97.711  1.00 27.28  ? 244 VAL C CG1 1 
ATOM   9424  C CG2 . VAL C 1 244 ? 112.872 147.095 99.264  1.00 27.28  ? 244 VAL C CG2 1 
ATOM   9425  N N   . LEU C 1 245 ? 114.500 142.780 99.194  1.00 23.92  ? 245 LEU C N   1 
ATOM   9426  C CA  . LEU C 1 245 ? 115.432 141.729 98.810  1.00 23.92  ? 245 LEU C CA  1 
ATOM   9427  C C   . LEU C 1 245 ? 115.486 141.642 97.293  1.00 23.92  ? 245 LEU C C   1 
ATOM   9428  O O   . LEU C 1 245 ? 114.443 141.560 96.637  1.00 23.92  ? 245 LEU C O   1 
ATOM   9429  C CB  . LEU C 1 245 ? 115.013 140.378 99.397  1.00 23.92  ? 245 LEU C CB  1 
ATOM   9430  C CG  . LEU C 1 245 ? 115.935 139.195 99.098  1.00 23.92  ? 245 LEU C CG  1 
ATOM   9431  C CD1 . LEU C 1 245 ? 117.293 139.386 99.750  1.00 23.92  ? 245 LEU C CD1 1 
ATOM   9432  C CD2 . LEU C 1 245 ? 115.301 137.888 99.532  1.00 23.92  ? 245 LEU C CD2 1 
ATOM   9433  N N   . VAL C 1 246 ? 116.695 141.658 96.740  1.00 23.24  ? 246 VAL C N   1 
ATOM   9434  C CA  . VAL C 1 246 ? 116.914 141.532 95.304  1.00 23.24  ? 246 VAL C CA  1 
ATOM   9435  C C   . VAL C 1 246 ? 117.880 140.380 95.068  1.00 23.24  ? 246 VAL C C   1 
ATOM   9436  O O   . VAL C 1 246 ? 118.931 140.303 95.714  1.00 23.24  ? 246 VAL C O   1 
ATOM   9437  C CB  . VAL C 1 246 ? 117.453 142.838 94.689  1.00 23.24  ? 246 VAL C CB  1 
ATOM   9438  C CG1 . VAL C 1 246 ? 117.825 142.629 93.231  1.00 23.24  ? 246 VAL C CG1 1 
ATOM   9439  C CG2 . VAL C 1 246 ? 116.423 143.945 94.813  1.00 23.24  ? 246 VAL C CG2 1 
ATOM   9440  N N   . ILE C 1 247 ? 117.520 139.485 94.153  1.00 22.81  ? 247 ILE C N   1 
ATOM   9441  C CA  . ILE C 1 247 ? 118.359 138.355 93.772  1.00 22.81  ? 247 ILE C CA  1 
ATOM   9442  C C   . ILE C 1 247 ? 118.689 138.495 92.294  1.00 22.81  ? 247 ILE C C   1 
ATOM   9443  O O   . ILE C 1 247 ? 117.784 138.547 91.452  1.00 22.81  ? 247 ILE C O   1 
ATOM   9444  C CB  . ILE C 1 247 ? 117.674 137.010 94.055  1.00 22.81  ? 247 ILE C CB  1 
ATOM   9445  C CG1 . ILE C 1 247 ? 117.348 136.880 95.543  1.00 22.81  ? 247 ILE C CG1 1 
ATOM   9446  C CG2 . ILE C 1 247 ? 118.556 135.860 93.600  1.00 22.81  ? 247 ILE C CG2 1 
ATOM   9447  C CD1 . ILE C 1 247 ? 116.401 135.752 95.861  1.00 22.81  ? 247 ILE C CD1 1 
ATOM   9448  N N   . ASN C 1 248 ? 119.981 138.550 91.980  1.00 24.75  ? 248 ASN C N   1 
ATOM   9449  C CA  . ASN C 1 248 ? 120.458 138.681 90.611  1.00 24.75  ? 248 ASN C CA  1 
ATOM   9450  C C   . ASN C 1 248 ? 121.436 137.553 90.330  1.00 24.75  ? 248 ASN C C   1 
ATOM   9451  O O   . ASN C 1 248 ? 122.405 137.371 91.073  1.00 24.75  ? 248 ASN C O   1 
ATOM   9452  C CB  . ASN C 1 248 ? 121.126 140.043 90.390  1.00 24.75  ? 248 ASN C CB  1 
ATOM   9453  C CG  . ASN C 1 248 ? 121.368 140.344 88.927  1.00 24.75  ? 248 ASN C CG  1 
ATOM   9454  O OD1 . ASN C 1 248 ? 122.385 139.950 88.360  1.00 24.75  ? 248 ASN C OD1 1 
ATOM   9455  N ND2 . ASN C 1 248 ? 120.433 141.051 88.308  1.00 24.75  ? 248 ASN C ND2 1 
ATOM   9456  N N   . SER C 1 249 ? 121.185 136.797 89.264  1.00 24.87  ? 249 SER C N   1 
ATOM   9457  C CA  . SER C 1 249 ? 122.014 135.642 88.960  1.00 24.87  ? 249 SER C CA  1 
ATOM   9458  C C   . SER C 1 249 ? 121.914 135.314 87.479  1.00 24.87  ? 249 SER C C   1 
ATOM   9459  O O   . SER C 1 249 ? 120.954 135.697 86.807  1.00 24.87  ? 249 SER C O   1 
ATOM   9460  C CB  . SER C 1 249 ? 121.605 134.426 89.799  1.00 24.87  ? 249 SER C CB  1 
ATOM   9461  O OG  . SER C 1 249 ? 122.155 133.234 89.270  1.00 24.87  ? 249 SER C OG  1 
ATOM   9462  N N   . ASN C 1 250 ? 122.924 134.599 86.981  1.00 26.57  ? 250 ASN C N   1 
ATOM   9463  C CA  . ASN C 1 250 ? 122.943 134.106 85.609  1.00 26.57  ? 250 ASN C CA  1 
ATOM   9464  C C   . ASN C 1 250 ? 123.471 132.677 85.548  1.00 26.57  ? 250 ASN C C   1 
ATOM   9465  O O   . ASN C 1 250 ? 124.005 132.249 84.522  1.00 26.57  ? 250 ASN C O   1 
ATOM   9466  C CB  . ASN C 1 250 ? 123.764 135.028 84.706  1.00 26.57  ? 250 ASN C CB  1 
ATOM   9467  C CG  . ASN C 1 250 ? 125.241 135.012 85.040  1.00 26.57  ? 250 ASN C CG  1 
ATOM   9468  O OD1 . ASN C 1 250 ? 125.625 134.910 86.204  1.00 26.57  ? 250 ASN C OD1 1 
ATOM   9469  N ND2 . ASN C 1 250 ? 126.079 135.122 84.018  1.00 26.57  ? 250 ASN C ND2 1 
ATOM   9470  N N   . GLY C 1 251 ? 123.327 131.933 86.629  1.00 25.02  ? 251 GLY C N   1 
ATOM   9471  C CA  . GLY C 1 251 ? 123.738 130.543 86.683  1.00 25.02  ? 251 GLY C CA  1 
ATOM   9472  C C   . GLY C 1 251 ? 124.111 130.132 88.096  1.00 25.02  ? 251 GLY C C   1 
ATOM   9473  O O   . GLY C 1 251 ? 124.558 130.932 88.912  1.00 25.02  ? 251 GLY C O   1 
ATOM   9474  N N   . ASN C 1 252 ? 123.898 128.845 88.389  1.00 23.46  ? 252 ASN C N   1 
ATOM   9475  C CA  . ASN C 1 252 ? 124.351 128.207 89.629  1.00 23.46  ? 252 ASN C CA  1 
ATOM   9476  C C   . ASN C 1 252 ? 123.613 128.738 90.858  1.00 23.46  ? 252 ASN C C   1 
ATOM   9477  O O   . ASN C 1 252 ? 124.205 128.906 91.923  1.00 23.46  ? 252 ASN C O   1 
ATOM   9478  C CB  . ASN C 1 252 ? 125.865 128.349 89.813  1.00 23.46  ? 252 ASN C CB  1 
ATOM   9479  C CG  . ASN C 1 252 ? 126.651 127.724 88.684  1.00 23.46  ? 252 ASN C CG  1 
ATOM   9480  O OD1 . ASN C 1 252 ? 126.686 128.250 87.574  1.00 23.46  ? 252 ASN C OD1 1 
ATOM   9481  N ND2 . ASN C 1 252 ? 127.288 126.596 88.961  1.00 23.46  ? 252 ASN C ND2 1 
ATOM   9482  N N   . LEU C 1 253 ? 122.316 128.996 90.721  1.00 22.33  ? 253 LEU C N   1 
ATOM   9483  C CA  . LEU C 1 253 ? 121.502 129.500 91.819  1.00 22.33  ? 253 LEU C CA  1 
ATOM   9484  C C   . LEU C 1 253 ? 120.585 128.403 92.341  1.00 22.33  ? 253 LEU C C   1 
ATOM   9485  O O   . LEU C 1 253 ? 119.849 127.782 91.567  1.00 22.33  ? 253 LEU C O   1 
ATOM   9486  C CB  . LEU C 1 253 ? 120.673 130.709 91.381  1.00 22.33  ? 253 LEU C CB  1 
ATOM   9487  C CG  . LEU C 1 253 ? 119.582 131.149 92.361  1.00 22.33  ? 253 LEU C CG  1 
ATOM   9488  C CD1 . LEU C 1 253 ? 120.177 131.878 93.554  1.00 22.33  ? 253 LEU C CD1 1 
ATOM   9489  C CD2 . LEU C 1 253 ? 118.545 132.014 91.667  1.00 22.33  ? 253 LEU C CD2 1 
ATOM   9490  N N   . ILE C 1 254 ? 120.634 128.170 93.649  1.00 21.09  ? 254 ILE C N   1 
ATOM   9491  C CA  . ILE C 1 254 ? 119.675 127.320 94.343  1.00 21.09  ? 254 ILE C CA  1 
ATOM   9492  C C   . ILE C 1 254 ? 118.696 128.264 95.031  1.00 21.09  ? 254 ILE C C   1 
ATOM   9493  O O   . ILE C 1 254 ? 118.969 128.783 96.116  1.00 21.09  ? 254 ILE C O   1 
ATOM   9494  C CB  . ILE C 1 254 ? 120.359 126.377 95.337  1.00 21.09  ? 254 ILE C CB  1 
ATOM   9495  C CG1 . ILE C 1 254 ? 121.594 125.733 94.701  1.00 21.09  ? 254 ILE C CG1 1 
ATOM   9496  C CG2 . ILE C 1 254 ? 119.389 125.312 95.819  1.00 21.09  ? 254 ILE C CG2 1 
ATOM   9497  C CD1 . ILE C 1 254 ? 121.276 124.709 93.639  1.00 21.09  ? 254 ILE C CD1 1 
ATOM   9498  N N   . ALA C 1 255 ? 117.551 128.490 94.394  1.00 21.68  ? 255 ALA C N   1 
ATOM   9499  C CA  . ALA C 1 255 ? 116.649 129.543 94.823  1.00 21.68  ? 255 ALA C CA  1 
ATOM   9500  C C   . ALA C 1 255 ? 115.930 129.168 96.118  1.00 21.68  ? 255 ALA C C   1 
ATOM   9501  O O   . ALA C 1 255 ? 115.693 127.989 96.390  1.00 21.68  ? 255 ALA C O   1 
ATOM   9502  C CB  . ALA C 1 255 ? 115.624 129.835 93.732  1.00 21.68  ? 255 ALA C CB  1 
ATOM   9503  N N   . PRO C 1 256 ? 115.577 130.156 96.935  1.00 21.54  ? 256 PRO C N   1 
ATOM   9504  C CA  . PRO C 1 256 ? 114.727 129.892 98.096  1.00 21.54  ? 256 PRO C CA  1 
ATOM   9505  C C   . PRO C 1 256 ? 113.257 129.813 97.709  1.00 21.54  ? 256 PRO C C   1 
ATOM   9506  O O   . PRO C 1 256 ? 112.830 130.294 96.658  1.00 21.54  ? 256 PRO C O   1 
ATOM   9507  C CB  . PRO C 1 256 ? 114.989 131.096 99.006  1.00 21.54  ? 256 PRO C CB  1 
ATOM   9508  C CG  . PRO C 1 256 ? 115.349 132.189 98.070  1.00 21.54  ? 256 PRO C CG  1 
ATOM   9509  C CD  . PRO C 1 256 ? 116.050 131.551 96.900  1.00 21.54  ? 256 PRO C CD  1 
ATOM   9510  N N   . ARG C 1 257 ? 112.480 129.186 98.589  1.00 20.89  ? 257 ARG C N   1 
ATOM   9511  C CA  . ARG C 1 257 ? 111.041 129.061 98.408  1.00 20.89  ? 257 ARG C CA  1 
ATOM   9512  C C   . ARG C 1 257 ? 110.246 129.964 99.340  1.00 20.89  ? 257 ARG C C   1 
ATOM   9513  O O   . ARG C 1 257 ? 109.017 130.013 99.234  1.00 20.89  ? 257 ARG C O   1 
ATOM   9514  C CB  . ARG C 1 257 ? 110.607 127.605 98.610  1.00 20.89  ? 257 ARG C CB  1 
ATOM   9515  C CG  . ARG C 1 257 ? 111.062 126.663 97.512  1.00 20.89  ? 257 ARG C CG  1 
ATOM   9516  C CD  . ARG C 1 257 ? 110.407 125.305 97.658  1.00 20.89  ? 257 ARG C CD  1 
ATOM   9517  N NE  . ARG C 1 257 ? 110.976 124.318 96.749  1.00 20.89  ? 257 ARG C NE  1 
ATOM   9518  C CZ  . ARG C 1 257 ? 110.527 124.082 95.524  1.00 20.89  ? 257 ARG C CZ  1 
ATOM   9519  N NH1 . ARG C 1 257 ? 109.509 124.758 95.018  1.00 20.89  ? 257 ARG C NH1 1 
ATOM   9520  N NH2 . ARG C 1 257 ? 111.116 123.145 94.787  1.00 20.89  ? 257 ARG C NH2 1 
ATOM   9521  N N   . GLY C 1 258 ? 110.910 130.682 100.239 1.00 19.78  ? 258 GLY C N   1 
ATOM   9522  C CA  . GLY C 1 258 ? 110.211 131.498 101.212 1.00 19.78  ? 258 GLY C CA  1 
ATOM   9523  C C   . GLY C 1 258 ? 111.172 131.971 102.283 1.00 19.78  ? 258 GLY C C   1 
ATOM   9524  O O   . GLY C 1 258 ? 112.382 132.030 102.063 1.00 19.78  ? 258 GLY C O   1 
ATOM   9525  N N   . PHE C 1 259 ? 110.616 132.297 103.447 1.00 19.55  ? 259 PHE C N   1 
ATOM   9526  C CA  . PHE C 1 259 ? 111.399 132.826 104.553 1.00 19.55  ? 259 PHE C CA  1 
ATOM   9527  C C   . PHE C 1 259 ? 111.021 132.124 105.850 1.00 19.55  ? 259 PHE C C   1 
ATOM   9528  O O   . PHE C 1 259 ? 109.934 131.558 105.985 1.00 19.55  ? 259 PHE C O   1 
ATOM   9529  C CB  . PHE C 1 259 ? 111.212 134.345 104.702 1.00 19.55  ? 259 PHE C CB  1 
ATOM   9530  C CG  . PHE C 1 259 ? 109.811 134.755 105.059 1.00 19.55  ? 259 PHE C CG  1 
ATOM   9531  C CD1 . PHE C 1 259 ? 108.859 134.948 104.074 1.00 19.55  ? 259 PHE C CD1 1 
ATOM   9532  C CD2 . PHE C 1 259 ? 109.448 134.959 106.380 1.00 19.55  ? 259 PHE C CD2 1 
ATOM   9533  C CE1 . PHE C 1 259 ? 107.574 135.325 104.398 1.00 19.55  ? 259 PHE C CE1 1 
ATOM   9534  C CE2 . PHE C 1 259 ? 108.164 135.335 106.710 1.00 19.55  ? 259 PHE C CE2 1 
ATOM   9535  C CZ  . PHE C 1 259 ? 107.226 135.520 105.717 1.00 19.55  ? 259 PHE C CZ  1 
ATOM   9536  N N   . PHE C 1 260 ? 111.945 132.171 106.806 1.00 21.76  ? 260 PHE C N   1 
ATOM   9537  C CA  . PHE C 1 260 ? 111.731 131.651 108.149 1.00 21.76  ? 260 PHE C CA  1 
ATOM   9538  C C   . PHE C 1 260 ? 111.449 132.807 109.100 1.00 21.76  ? 260 PHE C C   1 
ATOM   9539  O O   . PHE C 1 260 ? 112.161 133.816 109.082 1.00 21.76  ? 260 PHE C O   1 
ATOM   9540  C CB  . PHE C 1 260 ? 112.953 130.874 108.643 1.00 21.76  ? 260 PHE C CB  1 
ATOM   9541  C CG  . PHE C 1 260 ? 113.098 129.508 108.041 1.00 21.76  ? 260 PHE C CG  1 
ATOM   9542  C CD1 . PHE C 1 260 ? 112.453 128.419 108.600 1.00 21.76  ? 260 PHE C CD1 1 
ATOM   9543  C CD2 . PHE C 1 260 ? 113.899 129.308 106.930 1.00 21.76  ? 260 PHE C CD2 1 
ATOM   9544  C CE1 . PHE C 1 260 ? 112.590 127.160 108.054 1.00 21.76  ? 260 PHE C CE1 1 
ATOM   9545  C CE2 . PHE C 1 260 ? 114.040 128.051 106.380 1.00 21.76  ? 260 PHE C CE2 1 
ATOM   9546  C CZ  . PHE C 1 260 ? 113.385 126.976 106.944 1.00 21.76  ? 260 PHE C CZ  1 
ATOM   9547  N N   . LYS C 1 261 ? 110.414 132.661 109.923 1.00 25.79  ? 261 LYS C N   1 
ATOM   9548  C CA  . LYS C 1 261 ? 110.203 133.602 111.013 1.00 25.79  ? 261 LYS C CA  1 
ATOM   9549  C C   . LYS C 1 261 ? 111.312 133.445 112.044 1.00 25.79  ? 261 LYS C C   1 
ATOM   9550  O O   . LYS C 1 261 ? 111.616 132.331 112.481 1.00 25.79  ? 261 LYS C O   1 
ATOM   9551  C CB  . LYS C 1 261 ? 108.843 133.376 111.669 1.00 25.79  ? 261 LYS C CB  1 
ATOM   9552  C CG  . LYS C 1 261 ? 107.670 134.021 110.953 1.00 25.79  ? 261 LYS C CG  1 
ATOM   9553  C CD  . LYS C 1 261 ? 106.363 133.628 111.624 1.00 25.79  ? 261 LYS C CD  1 
ATOM   9554  C CE  . LYS C 1 261 ? 105.162 134.236 110.926 1.00 25.79  ? 261 LYS C CE  1 
ATOM   9555  N NZ  . LYS C 1 261 ? 104.975 135.663 111.299 1.00 25.79  ? 261 LYS C NZ  1 
ATOM   9556  N N   . ILE C 1 262 ? 111.917 134.562 112.437 1.00 27.40  ? 262 ILE C N   1 
ATOM   9557  C CA  . ILE C 1 262 ? 113.000 134.574 113.412 1.00 27.40  ? 262 ILE C CA  1 
ATOM   9558  C C   . ILE C 1 262 ? 112.542 135.377 114.621 1.00 27.40  ? 262 ILE C C   1 
ATOM   9559  O O   . ILE C 1 262 ? 112.044 136.500 114.478 1.00 27.40  ? 262 ILE C O   1 
ATOM   9560  C CB  . ILE C 1 262 ? 114.300 135.141 112.809 1.00 27.40  ? 262 ILE C CB  1 
ATOM   9561  C CG1 . ILE C 1 262 ? 115.391 135.254 113.877 1.00 27.40  ? 262 ILE C CG1 1 
ATOM   9562  C CG2 . ILE C 1 262 ? 114.052 136.465 112.115 1.00 27.40  ? 262 ILE C CG2 1 
ATOM   9563  C CD1 . ILE C 1 262 ? 116.780 135.417 113.307 1.00 27.40  ? 262 ILE C CD1 1 
ATOM   9564  N N   . ARG C 1 263 ? 112.693 134.793 115.806 1.00 30.85  ? 263 ARG C N   1 
ATOM   9565  C CA  . ARG C 1 263 ? 112.166 135.360 117.037 1.00 30.85  ? 263 ARG C CA  1 
ATOM   9566  C C   . ARG C 1 263 ? 113.287 135.508 118.056 1.00 30.85  ? 263 ARG C C   1 
ATOM   9567  O O   . ARG C 1 263 ? 114.395 134.996 117.880 1.00 30.85  ? 263 ARG C O   1 
ATOM   9568  C CB  . ARG C 1 263 ? 111.039 134.489 117.609 1.00 30.85  ? 263 ARG C CB  1 
ATOM   9569  C CG  . ARG C 1 263 ? 109.785 134.468 116.755 1.00 30.85  ? 263 ARG C CG  1 
ATOM   9570  C CD  . ARG C 1 263 ? 108.755 133.491 117.292 1.00 30.85  ? 263 ARG C CD  1 
ATOM   9571  N NE  . ARG C 1 263 ? 107.789 133.112 116.267 1.00 30.85  ? 263 ARG C NE  1 
ATOM   9572  C CZ  . ARG C 1 263 ? 107.020 132.033 116.322 1.00 30.85  ? 263 ARG C CZ  1 
ATOM   9573  N NH1 . ARG C 1 263 ? 107.070 131.199 117.348 1.00 30.85  ? 263 ARG C NH1 1 
ATOM   9574  N NH2 . ARG C 1 263 ? 106.180 131.784 115.322 1.00 30.85  ? 263 ARG C NH2 1 
ATOM   9575  N N   . THR C 1 264 ? 112.983 136.228 119.131 1.00 32.75  ? 264 THR C N   1 
ATOM   9576  C CA  . THR C 1 264 ? 113.890 136.407 120.255 1.00 32.75  ? 264 THR C CA  1 
ATOM   9577  C C   . THR C 1 264 ? 113.306 135.699 121.470 1.00 32.75  ? 264 THR C C   1 
ATOM   9578  O O   . THR C 1 264 ? 112.155 135.948 121.841 1.00 32.75  ? 264 THR C O   1 
ATOM   9579  C CB  . THR C 1 264 ? 114.106 137.891 120.558 1.00 32.75  ? 264 THR C CB  1 
ATOM   9580  O OG1 . THR C 1 264 ? 114.760 138.518 119.449 1.00 32.75  ? 264 THR C OG1 1 
ATOM   9581  C CG2 . THR C 1 264 ? 114.963 138.062 121.801 1.00 32.75  ? 264 THR C CG2 1 
ATOM   9582  N N   . GLY C 1 265 ? 114.091 134.826 122.079 1.00 31.36  ? 265 GLY C N   1 
ATOM   9583  C CA  . GLY C 1 265 ? 113.608 134.050 123.195 1.00 31.36  ? 265 GLY C CA  1 
ATOM   9584  C C   . GLY C 1 265 ? 114.729 133.456 124.011 1.00 31.36  ? 265 GLY C C   1 
ATOM   9585  O O   . GLY C 1 265 ? 115.837 133.991 124.063 1.00 31.36  ? 265 GLY C O   1 
ATOM   9586  N N   . ARG C 1 266 ? 114.426 132.328 124.653 1.00 30.60  ? 266 ARG C N   1 
ATOM   9587  C CA  . ARG C 1 266 ? 115.351 131.662 125.560 1.00 30.60  ? 266 ARG C CA  1 
ATOM   9588  C C   . ARG C 1 266 ? 115.623 130.220 125.137 1.00 30.60  ? 266 ARG C C   1 
ATOM   9589  O O   . ARG C 1 266 ? 115.895 129.360 125.976 1.00 30.60  ? 266 ARG C O   1 
ATOM   9590  C CB  . ARG C 1 266 ? 114.819 131.715 126.991 1.00 30.60  ? 266 ARG C CB  1 
ATOM   9591  C CG  . ARG C 1 266 ? 113.525 130.947 127.207 1.00 30.60  ? 266 ARG C CG  1 
ATOM   9592  C CD  . ARG C 1 266 ? 113.077 131.023 128.654 1.00 30.60  ? 266 ARG C CD  1 
ATOM   9593  N NE  . ARG C 1 266 ? 111.797 130.356 128.861 1.00 30.60  ? 266 ARG C NE  1 
ATOM   9594  C CZ  . ARG C 1 266 ? 111.663 129.066 129.134 1.00 30.60  ? 266 ARG C CZ  1 
ATOM   9595  N NH1 . ARG C 1 266 ? 112.715 128.271 129.250 1.00 30.60  ? 266 ARG C NH1 1 
ATOM   9596  N NH2 . ARG C 1 266 ? 110.444 128.560 129.296 1.00 30.60  ? 266 ARG C NH2 1 
ATOM   9597  N N   . SER C 1 267 ? 115.566 129.946 123.838 1.00 23.63  ? 267 SER C N   1 
ATOM   9598  C CA  . SER C 1 267 ? 115.810 128.602 123.341 1.00 23.63  ? 267 SER C CA  1 
ATOM   9599  C C   . SER C 1 267 ? 117.307 128.350 123.176 1.00 23.63  ? 267 SER C C   1 
ATOM   9600  O O   . SER C 1 267 ? 118.119 129.277 123.139 1.00 23.63  ? 267 SER C O   1 
ATOM   9601  C CB  . SER C 1 267 ? 115.087 128.383 122.014 1.00 23.63  ? 267 SER C CB  1 
ATOM   9602  O OG  . SER C 1 267 ? 113.684 128.354 122.200 1.00 23.63  ? 267 SER C OG  1 
ATOM   9603  N N   . SER C 1 268 ? 117.665 127.074 123.078 1.00 21.87  ? 268 SER C N   1 
ATOM   9604  C CA  . SER C 1 268 ? 119.061 126.674 122.939 1.00 21.87  ? 268 SER C CA  1 
ATOM   9605  C C   . SER C 1 268 ? 119.113 125.296 122.287 1.00 21.87  ? 268 SER C C   1 
ATOM   9606  O O   . SER C 1 268 ? 118.094 124.763 121.837 1.00 21.87  ? 268 SER C O   1 
ATOM   9607  C CB  . SER C 1 268 ? 119.771 126.691 124.297 1.00 21.87  ? 268 SER C CB  1 
ATOM   9608  O OG  . SER C 1 268 ? 121.178 126.674 124.136 1.00 21.87  ? 268 SER C OG  1 
ATOM   9609  N N   . ILE C 1 269 ? 120.313 124.719 122.237 1.00 21.61  ? 269 ILE C N   1 
ATOM   9610  C CA  . ILE C 1 269 ? 120.547 123.411 121.637 1.00 21.61  ? 269 ILE C CA  1 
ATOM   9611  C C   . ILE C 1 269 ? 121.597 122.684 122.467 1.00 21.61  ? 269 ILE C C   1 
ATOM   9612  O O   . ILE C 1 269 ? 122.496 123.303 123.045 1.00 21.61  ? 269 ILE C O   1 
ATOM   9613  C CB  . ILE C 1 269 ? 120.983 123.532 120.157 1.00 21.61  ? 269 ILE C CB  1 
ATOM   9614  C CG1 . ILE C 1 269 ? 121.029 122.159 119.484 1.00 21.61  ? 269 ILE C CG1 1 
ATOM   9615  C CG2 . ILE C 1 269 ? 122.324 124.243 120.041 1.00 21.61  ? 269 ILE C CG2 1 
ATOM   9616  C CD1 . ILE C 1 269 ? 120.969 122.221 117.982 1.00 21.61  ? 269 ILE C CD1 1 
ATOM   9617  N N   . MET C 1 270 ? 121.471 121.360 122.540 1.00 24.13  ? 270 MET C N   1 
ATOM   9618  C CA  . MET C 1 270 ? 122.361 120.545 123.353 1.00 24.13  ? 270 MET C CA  1 
ATOM   9619  C C   . MET C 1 270 ? 122.713 119.262 122.615 1.00 24.13  ? 270 MET C C   1 
ATOM   9620  O O   . MET C 1 270 ? 121.930 118.756 121.808 1.00 24.13  ? 270 MET C O   1 
ATOM   9621  C CB  . MET C 1 270 ? 121.726 120.203 124.707 1.00 24.13  ? 270 MET C CB  1 
ATOM   9622  C CG  . MET C 1 270 ? 122.721 119.875 125.806 1.00 24.13  ? 270 MET C CG  1 
ATOM   9623  S SD  . MET C 1 270 ? 121.924 119.641 127.405 1.00 24.13  ? 270 MET C SD  1 
ATOM   9624  C CE  . MET C 1 270 ? 122.347 121.175 128.222 1.00 24.13  ? 270 MET C CE  1 
ATOM   9625  N N   . ARG C 1 271 ? 123.903 118.742 122.904 1.00 22.73  ? 271 ARG C N   1 
ATOM   9626  C CA  . ARG C 1 271 ? 124.348 117.442 122.418 1.00 22.73  ? 271 ARG C CA  1 
ATOM   9627  C C   . ARG C 1 271 ? 124.331 116.466 123.586 1.00 22.73  ? 271 ARG C C   1 
ATOM   9628  O O   . ARG C 1 271 ? 125.045 116.666 124.574 1.00 22.73  ? 271 ARG C O   1 
ATOM   9629  C CB  . ARG C 1 271 ? 125.752 117.524 121.818 1.00 22.73  ? 271 ARG C CB  1 
ATOM   9630  C CG  . ARG C 1 271 ? 125.879 118.418 120.599 1.00 22.73  ? 271 ARG C CG  1 
ATOM   9631  C CD  . ARG C 1 271 ? 127.272 118.305 120.000 1.00 22.73  ? 271 ARG C CD  1 
ATOM   9632  N NE  . ARG C 1 271 ? 127.490 119.245 118.909 1.00 22.73  ? 271 ARG C NE  1 
ATOM   9633  C CZ  . ARG C 1 271 ? 128.107 120.412 119.037 1.00 22.73  ? 271 ARG C CZ  1 
ATOM   9634  N NH1 . ARG C 1 271 ? 128.573 120.822 120.205 1.00 22.73  ? 271 ARG C NH1 1 
ATOM   9635  N NH2 . ARG C 1 271 ? 128.261 121.186 117.967 1.00 22.73  ? 271 ARG C NH2 1 
ATOM   9636  N N   . SER C 1 272 ? 123.524 115.415 123.473 1.00 26.19  ? 272 SER C N   1 
ATOM   9637  C CA  . SER C 1 272 ? 123.403 114.453 124.558 1.00 26.19  ? 272 SER C CA  1 
ATOM   9638  C C   . SER C 1 272 ? 122.881 113.136 124.005 1.00 26.19  ? 272 SER C C   1 
ATOM   9639  O O   . SER C 1 272 ? 122.279 113.086 122.930 1.00 26.19  ? 272 SER C O   1 
ATOM   9640  C CB  . SER C 1 272 ? 122.483 114.974 125.668 1.00 26.19  ? 272 SER C CB  1 
ATOM   9641  O OG  . SER C 1 272 ? 122.358 114.029 126.715 1.00 26.19  ? 272 SER C OG  1 
ATOM   9642  N N   . ASP C 1 273 ? 123.123 112.067 124.762 1.00 30.22  ? 273 ASP C N   1 
ATOM   9643  C CA  . ASP C 1 273 ? 122.610 110.746 124.438 1.00 30.22  ? 273 ASP C CA  1 
ATOM   9644  C C   . ASP C 1 273 ? 121.667 110.202 125.501 1.00 30.22  ? 273 ASP C C   1 
ATOM   9645  O O   . ASP C 1 273 ? 121.204 109.064 125.372 1.00 30.22  ? 273 ASP C O   1 
ATOM   9646  C CB  . ASP C 1 273 ? 123.766 109.758 124.230 1.00 30.22  ? 273 ASP C CB  1 
ATOM   9647  C CG  . ASP C 1 273 ? 124.486 109.970 122.914 1.00 30.22  ? 273 ASP C CG  1 
ATOM   9648  O OD1 . ASP C 1 273 ? 123.810 110.236 121.898 1.00 30.22  ? 273 ASP C OD1 1 
ATOM   9649  O OD2 . ASP C 1 273 ? 125.730 109.870 122.896 1.00 30.22  ? 273 ASP C OD2 1 
ATOM   9650  N N   . ALA C 1 274 ? 121.373 110.975 126.541 1.00 28.87  ? 274 ALA C N   1 
ATOM   9651  C CA  . ALA C 1 274 ? 120.506 110.495 127.604 1.00 28.87  ? 274 ALA C CA  1 
ATOM   9652  C C   . ALA C 1 274 ? 119.060 110.422 127.117 1.00 28.87  ? 274 ALA C C   1 
ATOM   9653  O O   . ALA C 1 274 ? 118.606 111.303 126.381 1.00 28.87  ? 274 ALA C O   1 
ATOM   9654  C CB  . ALA C 1 274 ? 120.600 111.408 128.825 1.00 28.87  ? 274 ALA C CB  1 
ATOM   9655  N N   . PRO C 1 275 ? 118.317 109.390 127.506 1.00 29.88  ? 275 PRO C N   1 
ATOM   9656  C CA  . PRO C 1 275 ? 116.912 109.298 127.102 1.00 29.88  ? 275 PRO C CA  1 
ATOM   9657  C C   . PRO C 1 275 ? 116.056 110.339 127.808 1.00 29.88  ? 275 PRO C C   1 
ATOM   9658  O O   . PRO C 1 275 ? 116.443 110.931 128.816 1.00 29.88  ? 275 PRO C O   1 
ATOM   9659  C CB  . PRO C 1 275 ? 116.511 107.878 127.514 1.00 29.88  ? 275 PRO C CB  1 
ATOM   9660  C CG  . PRO C 1 275 ? 117.491 107.491 128.561 1.00 29.88  ? 275 PRO C CG  1 
ATOM   9661  C CD  . PRO C 1 275 ? 118.768 108.194 128.236 1.00 29.88  ? 275 PRO C CD  1 
ATOM   9662  N N   . ILE C 1 276 ? 114.868 110.555 127.252 1.00 32.26  ? 276 ILE C N   1 
ATOM   9663  C CA  . ILE C 1 276 ? 113.912 111.531 127.760 1.00 32.26  ? 276 ILE C CA  1 
ATOM   9664  C C   . ILE C 1 276 ? 112.751 110.767 128.379 1.00 32.26  ? 276 ILE C C   1 
ATOM   9665  O O   . ILE C 1 276 ? 112.138 109.917 127.723 1.00 32.26  ? 276 ILE C O   1 
ATOM   9666  C CB  . ILE C 1 276 ? 113.427 112.477 126.651 1.00 32.26  ? 276 ILE C CB  1 
ATOM   9667  C CG1 . ILE C 1 276 ? 114.616 113.194 126.012 1.00 32.26  ? 276 ILE C CG1 1 
ATOM   9668  C CG2 . ILE C 1 276 ? 112.427 113.480 127.203 1.00 32.26  ? 276 ILE C CG2 1 
ATOM   9669  C CD1 . ILE C 1 276 ? 114.248 114.044 124.825 1.00 32.26  ? 276 ILE C CD1 1 
ATOM   9670  N N   . GLU C 1 277 ? 112.448 111.069 129.640 1.00 37.74  ? 277 GLU C N   1 
ATOM   9671  C CA  . GLU C 1 277 ? 111.429 110.353 130.391 1.00 37.74  ? 277 GLU C CA  1 
ATOM   9672  C C   . GLU C 1 277 ? 110.495 111.346 131.068 1.00 37.74  ? 277 GLU C C   1 
ATOM   9673  O O   . GLU C 1 277 ? 110.831 112.517 131.255 1.00 37.74  ? 277 GLU C O   1 
ATOM   9674  C CB  . GLU C 1 277 ? 112.055 109.421 131.438 1.00 37.74  ? 277 GLU C CB  1 
ATOM   9675  C CG  . GLU C 1 277 ? 112.858 108.271 130.847 1.00 37.74  ? 277 GLU C CG  1 
ATOM   9676  C CD  . GLU C 1 277 ? 111.997 107.281 130.088 1.00 37.74  ? 277 GLU C CD  1 
ATOM   9677  O OE1 . GLU C 1 277 ? 110.821 107.096 130.469 1.00 37.74  ? 277 GLU C OE1 1 
ATOM   9678  O OE2 . GLU C 1 277 ? 112.497 106.688 129.110 1.00 37.74  ? 277 GLU C OE2 1 
ATOM   9679  N N   . THR C 1 278 ? 109.314 110.857 131.442 1.00 39.77  ? 278 THR C N   1 
ATOM   9680  C CA  . THR C 1 278 ? 108.293 111.688 132.075 1.00 39.77  ? 278 THR C CA  1 
ATOM   9681  C C   . THR C 1 278 ? 108.707 111.984 133.511 1.00 39.77  ? 278 THR C C   1 
ATOM   9682  O O   . THR C 1 278 ? 108.728 111.086 134.358 1.00 39.77  ? 278 THR C O   1 
ATOM   9683  C CB  . THR C 1 278 ? 106.934 110.995 132.030 1.00 39.77  ? 278 THR C CB  1 
ATOM   9684  O OG1 . THR C 1 278 ? 106.558 110.764 130.667 1.00 39.77  ? 278 THR C OG1 1 
ATOM   9685  C CG2 . THR C 1 278 ? 105.879 111.857 132.698 1.00 39.77  ? 278 THR C CG2 1 
ATOM   9686  N N   . CYS C 1 279 ? 109.020 113.248 133.784 1.00 38.44  ? 279 CYS C N   1 
ATOM   9687  C CA  . CYS C 1 279 ? 109.529 113.701 135.073 1.00 38.44  ? 279 CYS C CA  1 
ATOM   9688  C C   . CYS C 1 279 ? 109.649 115.218 135.028 1.00 38.44  ? 279 CYS C C   1 
ATOM   9689  O O   . CYS C 1 279 ? 109.508 115.838 133.971 1.00 38.44  ? 279 CYS C O   1 
ATOM   9690  C CB  . CYS C 1 279 ? 110.860 113.018 135.420 1.00 38.44  ? 279 CYS C CB  1 
ATOM   9691  S SG  . CYS C 1 279 ? 112.277 113.424 134.360 1.00 38.44  ? 279 CYS C SG  1 
ATOM   9692  N N   . ILE C 1 280 ? 109.895 115.812 136.195 1.00 35.55  ? 280 ILE C N   1 
ATOM   9693  C CA  . ILE C 1 280 ? 109.945 117.261 136.355 1.00 35.55  ? 280 ILE C CA  1 
ATOM   9694  C C   . ILE C 1 280 ? 111.306 117.649 136.916 1.00 35.55  ? 280 ILE C C   1 
ATOM   9695  O O   . ILE C 1 280 ? 111.735 117.112 137.944 1.00 35.55  ? 280 ILE C O   1 
ATOM   9696  C CB  . ILE C 1 280 ? 108.819 117.770 137.273 1.00 35.55  ? 280 ILE C CB  1 
ATOM   9697  C CG1 . ILE C 1 280 ? 107.457 117.293 136.767 1.00 35.55  ? 280 ILE C CG1 1 
ATOM   9698  C CG2 . ILE C 1 280 ? 108.854 119.286 137.370 1.00 35.55  ? 280 ILE C CG2 1 
ATOM   9699  C CD1 . ILE C 1 280 ? 106.287 117.891 137.513 1.00 35.55  ? 280 ILE C CD1 1 
ATOM   9700  N N   . SER C 1 281 ? 111.977 118.585 136.246 1.00 32.78  ? 281 SER C N   1 
ATOM   9701  C CA  . SER C 1 281 ? 113.253 119.106 136.713 1.00 32.78  ? 281 SER C CA  1 
ATOM   9702  C C   . SER C 1 281 ? 113.530 120.425 136.007 1.00 32.78  ? 281 SER C C   1 
ATOM   9703  O O   . SER C 1 281 ? 113.232 120.572 134.820 1.00 32.78  ? 281 SER C O   1 
ATOM   9704  C CB  . SER C 1 281 ? 114.395 118.116 136.459 1.00 32.78  ? 281 SER C CB  1 
ATOM   9705  O OG  . SER C 1 281 ? 115.528 118.429 137.249 1.00 32.78  ? 281 SER C OG  1 
ATOM   9706  N N   . GLU C 1 282 ? 114.100 121.375 136.744 1.00 32.98  ? 282 GLU C N   1 
ATOM   9707  C CA  . GLU C 1 282 ? 114.380 122.702 136.213 1.00 32.98  ? 282 GLU C CA  1 
ATOM   9708  C C   . GLU C 1 282 ? 115.783 122.839 135.636 1.00 32.98  ? 282 GLU C C   1 
ATOM   9709  O O   . GLU C 1 282 ? 116.105 123.897 135.087 1.00 32.98  ? 282 GLU C O   1 
ATOM   9710  C CB  . GLU C 1 282 ? 114.180 123.758 137.305 1.00 32.98  ? 282 GLU C CB  1 
ATOM   9711  C CG  . GLU C 1 282 ? 112.726 124.057 137.618 1.00 32.98  ? 282 GLU C CG  1 
ATOM   9712  C CD  . GLU C 1 282 ? 112.218 125.288 136.899 1.00 32.98  ? 282 GLU C CD  1 
ATOM   9713  O OE1 . GLU C 1 282 ? 113.008 125.917 136.164 1.00 32.98  ? 282 GLU C OE1 1 
ATOM   9714  O OE2 . GLU C 1 282 ? 111.029 125.628 137.068 1.00 32.98  ? 282 GLU C OE2 1 
ATOM   9715  N N   . CYS C 1 283 ? 116.619 121.810 135.741 1.00 30.01  ? 283 CYS C N   1 
ATOM   9716  C CA  . CYS C 1 283 ? 117.994 121.865 135.266 1.00 30.01  ? 283 CYS C CA  1 
ATOM   9717  C C   . CYS C 1 283 ? 118.259 120.675 134.359 1.00 30.01  ? 283 CYS C C   1 
ATOM   9718  O O   . CYS C 1 283 ? 117.872 119.548 134.681 1.00 30.01  ? 283 CYS C O   1 
ATOM   9719  C CB  . CYS C 1 283 ? 118.981 121.873 136.437 1.00 30.01  ? 283 CYS C CB  1 
ATOM   9720  S SG  . CYS C 1 283 ? 120.713 122.003 135.949 1.00 30.01  ? 283 CYS C SG  1 
ATOM   9721  N N   . ILE C 1 284 ? 118.920 120.925 133.230 1.00 26.99  ? 284 ILE C N   1 
ATOM   9722  C CA  . ILE C 1 284 ? 119.236 119.894 132.249 1.00 26.99  ? 284 ILE C CA  1 
ATOM   9723  C C   . ILE C 1 284 ? 120.729 119.948 131.954 1.00 26.99  ? 284 ILE C C   1 
ATOM   9724  O O   . ILE C 1 284 ? 121.284 121.029 131.733 1.00 26.99  ? 284 ILE C O   1 
ATOM   9725  C CB  . ILE C 1 284 ? 118.421 120.066 130.953 1.00 26.99  ? 284 ILE C CB  1 
ATOM   9726  C CG1 . ILE C 1 284 ? 116.923 119.964 131.243 1.00 26.99  ? 284 ILE C CG1 1 
ATOM   9727  C CG2 . ILE C 1 284 ? 118.825 119.027 129.922 1.00 26.99  ? 284 ILE C CG2 1 
ATOM   9728  C CD1 . ILE C 1 284 ? 116.050 120.511 130.139 1.00 26.99  ? 284 ILE C CD1 1 
ATOM   9729  N N   . THR C 1 285 ? 121.371 118.789 131.958 1.00 25.82  ? 285 THR C N   1 
ATOM   9730  C CA  . THR C 1 285 ? 122.770 118.619 131.604 1.00 25.82  ? 285 THR C CA  1 
ATOM   9731  C C   . THR C 1 285 ? 122.875 117.519 130.561 1.00 25.82  ? 285 THR C C   1 
ATOM   9732  O O   . THR C 1 285 ? 121.939 116.731 130.386 1.00 25.82  ? 285 THR C O   1 
ATOM   9733  C CB  . THR C 1 285 ? 123.628 118.260 132.829 1.00 25.82  ? 285 THR C CB  1 
ATOM   9734  O OG1 . THR C 1 285 ? 123.101 117.088 133.461 1.00 25.82  ? 285 THR C OG1 1 
ATOM   9735  C CG2 . THR C 1 285 ? 123.650 119.401 133.829 1.00 25.82  ? 285 THR C CG2 1 
ATOM   9736  N N   . PRO C 1 286 ? 123.989 117.451 129.828 1.00 25.43  ? 286 PRO C N   1 
ATOM   9737  C CA  . PRO C 1 286 ? 124.190 116.313 128.918 1.00 25.43  ? 286 PRO C CA  1 
ATOM   9738  C C   . PRO C 1 286 ? 124.150 114.967 129.618 1.00 25.43  ? 286 PRO C C   1 
ATOM   9739  O O   . PRO C 1 286 ? 123.763 113.973 128.994 1.00 25.43  ? 286 PRO C O   1 
ATOM   9740  C CB  . PRO C 1 286 ? 125.570 116.590 128.311 1.00 25.43  ? 286 PRO C CB  1 
ATOM   9741  C CG  . PRO C 1 286 ? 125.709 118.064 128.374 1.00 25.43  ? 286 PRO C CG  1 
ATOM   9742  C CD  . PRO C 1 286 ? 125.006 118.499 129.627 1.00 25.43  ? 286 PRO C CD  1 
ATOM   9743  N N   . ASN C 1 287 ? 124.543 114.903 130.892 1.00 27.95  ? 287 ASN C N   1 
ATOM   9744  C CA  . ASN C 1 287 ? 124.421 113.669 131.657 1.00 27.95  ? 287 ASN C CA  1 
ATOM   9745  C C   . ASN C 1 287 ? 122.973 113.347 131.999 1.00 27.95  ? 287 ASN C C   1 
ATOM   9746  O O   . ASN C 1 287 ? 122.633 112.172 132.167 1.00 27.95  ? 287 ASN C O   1 
ATOM   9747  C CB  . ASN C 1 287 ? 125.230 113.770 132.951 1.00 27.95  ? 287 ASN C CB  1 
ATOM   9748  C CG  . ASN C 1 287 ? 126.665 114.196 132.718 1.00 27.95  ? 287 ASN C CG  1 
ATOM   9749  O OD1 . ASN C 1 287 ? 126.932 115.352 132.395 1.00 27.95  ? 287 ASN C OD1 1 
ATOM   9750  N ND2 . ASN C 1 287 ? 127.598 113.271 132.900 1.00 27.95  ? 287 ASN C ND2 1 
ATOM   9751  N N   . GLY C 1 288 ? 122.119 114.362 132.108 1.00 26.58  ? 288 GLY C N   1 
ATOM   9752  C CA  . GLY C 1 288 ? 120.749 114.191 132.546 1.00 26.58  ? 288 GLY C CA  1 
ATOM   9753  C C   . GLY C 1 288 ? 120.299 115.347 133.414 1.00 26.58  ? 288 GLY C C   1 
ATOM   9754  O O   . GLY C 1 288 ? 121.027 116.331 133.564 1.00 26.58  ? 288 GLY C O   1 
ATOM   9755  N N   . SER C 1 289 ? 119.107 115.249 133.991 1.00 28.98  ? 289 SER C N   1 
ATOM   9756  C CA  . SER C 1 289 ? 118.588 116.295 134.860 1.00 28.98  ? 289 SER C CA  1 
ATOM   9757  C C   . SER C 1 289 ? 119.084 116.099 136.287 1.00 28.98  ? 289 SER C C   1 
ATOM   9758  O O   . SER C 1 289 ? 119.200 114.973 136.776 1.00 28.98  ? 289 SER C O   1 
ATOM   9759  C CB  . SER C 1 289 ? 117.060 116.307 134.837 1.00 28.98  ? 289 SER C CB  1 
ATOM   9760  O OG  . SER C 1 289 ? 116.571 116.724 133.575 1.00 28.98  ? 289 SER C OG  1 
ATOM   9761  N N   . ILE C 1 290 ? 119.376 117.212 136.954 1.00 28.60  ? 290 ILE C N   1 
ATOM   9762  C CA  . ILE C 1 290 ? 119.880 117.179 138.326 1.00 28.60  ? 290 ILE C CA  1 
ATOM   9763  C C   . ILE C 1 290 ? 119.050 118.115 139.197 1.00 28.60  ? 290 ILE C C   1 
ATOM   9764  O O   . ILE C 1 290 ? 118.522 119.119 138.698 1.00 28.60  ? 290 ILE C O   1 
ATOM   9765  C CB  . ILE C 1 290 ? 121.369 117.556 138.383 1.00 28.60  ? 290 ILE C CB  1 
ATOM   9766  C CG1 . ILE C 1 290 ? 121.603 118.921 137.737 1.00 28.60  ? 290 ILE C CG1 1 
ATOM   9767  C CG2 . ILE C 1 290 ? 122.218 116.496 137.702 1.00 28.60  ? 290 ILE C CG2 1 
ATOM   9768  C CD1 . ILE C 1 290 ? 122.967 119.503 138.022 1.00 28.60  ? 290 ILE C CD1 1 
ATOM   9769  N N   . PRO C 1 291 ? 118.895 117.824 140.488 1.00 29.29  ? 291 PRO C N   1 
ATOM   9770  C CA  . PRO C 1 291 ? 118.209 118.767 141.378 1.00 29.29  ? 291 PRO C CA  1 
ATOM   9771  C C   . PRO C 1 291 ? 119.045 120.013 141.624 1.00 29.29  ? 291 PRO C C   1 
ATOM   9772  O O   . PRO C 1 291 ? 120.277 119.982 141.585 1.00 29.29  ? 291 PRO C O   1 
ATOM   9773  C CB  . PRO C 1 291 ? 118.013 117.963 142.669 1.00 29.29  ? 291 PRO C CB  1 
ATOM   9774  C CG  . PRO C 1 291 ? 119.019 116.870 142.601 1.00 29.29  ? 291 PRO C CG  1 
ATOM   9775  C CD  . PRO C 1 291 ? 119.206 116.549 141.155 1.00 29.29  ? 291 PRO C CD  1 
ATOM   9776  N N   . ASN C 1 292 ? 118.355 121.122 141.888 1.00 30.90  ? 292 ASN C N   1 
ATOM   9777  C CA  . ASN C 1 292 ? 118.998 122.421 142.053 1.00 30.90  ? 292 ASN C CA  1 
ATOM   9778  C C   . ASN C 1 292 ? 118.846 122.960 143.472 1.00 30.90  ? 292 ASN C C   1 
ATOM   9779  O O   . ASN C 1 292 ? 118.903 124.171 143.691 1.00 30.90  ? 292 ASN C O   1 
ATOM   9780  C CB  . ASN C 1 292 ? 118.450 123.427 141.041 1.00 30.90  ? 292 ASN C CB  1 
ATOM   9781  C CG  . ASN C 1 292 ? 116.950 123.614 141.156 1.00 30.90  ? 292 ASN C CG  1 
ATOM   9782  O OD1 . ASN C 1 292 ? 116.273 122.880 141.873 1.00 30.90  ? 292 ASN C OD1 1 
ATOM   9783  N ND2 . ASN C 1 292 ? 116.424 124.605 140.447 1.00 30.90  ? 292 ASN C ND2 1 
ATOM   9784  N N   . ASP C 1 293 ? 118.651 122.073 144.449 1.00 32.28  ? 293 ASP C N   1 
ATOM   9785  C CA  . ASP C 1 293 ? 118.533 122.508 145.835 1.00 32.28  ? 293 ASP C CA  1 
ATOM   9786  C C   . ASP C 1 293 ? 119.870 122.910 146.442 1.00 32.28  ? 293 ASP C C   1 
ATOM   9787  O O   . ASP C 1 293 ? 119.887 123.656 147.427 1.00 32.28  ? 293 ASP C O   1 
ATOM   9788  C CB  . ASP C 1 293 ? 117.896 121.406 146.684 1.00 32.28  ? 293 ASP C CB  1 
ATOM   9789  C CG  . ASP C 1 293 ? 118.465 120.037 146.382 1.00 32.28  ? 293 ASP C CG  1 
ATOM   9790  O OD1 . ASP C 1 293 ? 119.367 119.943 145.524 1.00 32.28  ? 293 ASP C OD1 1 
ATOM   9791  O OD2 . ASP C 1 293 ? 118.013 119.054 147.004 1.00 32.28  ? 293 ASP C OD2 1 
ATOM   9792  N N   . LYS C 1 294 ? 120.994 122.435 145.877 1.00 27.94  ? 294 LYS C N   1 
ATOM   9793  C CA  . LYS C 1 294 ? 122.324 122.760 146.362 1.00 27.94  ? 294 LYS C CA  1 
ATOM   9794  C C   . LYS C 1 294 ? 122.916 123.921 145.571 1.00 27.94  ? 294 LYS C C   1 
ATOM   9795  O O   . LYS C 1 294 ? 122.618 124.090 144.385 1.00 27.94  ? 294 LYS C O   1 
ATOM   9796  C CB  . LYS C 1 294 ? 123.248 121.545 146.256 1.00 27.94  ? 294 LYS C CB  1 
ATOM   9797  C CG  . LYS C 1 294 ? 122.982 120.484 147.307 1.00 27.94  ? 294 LYS C CG  1 
ATOM   9798  C CD  . LYS C 1 294 ? 123.765 119.219 147.027 1.00 27.94  ? 294 LYS C CD  1 
ATOM   9799  C CE  . LYS C 1 294 ? 123.160 118.032 147.749 1.00 27.94  ? 294 LYS C CE  1 
ATOM   9800  N NZ  . LYS C 1 294 ? 124.129 116.912 147.864 1.00 27.94  ? 294 LYS C NZ  1 
ATOM   9801  N N   . PRO C 1 295 ? 123.759 124.745 146.202 1.00 24.48  ? 295 PRO C N   1 
ATOM   9802  C CA  . PRO C 1 295 ? 124.304 125.915 145.495 1.00 24.48  ? 295 PRO C CA  1 
ATOM   9803  C C   . PRO C 1 295 ? 125.385 125.592 144.477 1.00 24.48  ? 295 PRO C C   1 
ATOM   9804  O O   . PRO C 1 295 ? 125.690 126.454 143.643 1.00 24.48  ? 295 PRO C O   1 
ATOM   9805  C CB  . PRO C 1 295 ? 124.866 126.783 146.630 1.00 24.48  ? 295 PRO C CB  1 
ATOM   9806  C CG  . PRO C 1 295 ? 125.138 125.830 147.736 1.00 24.48  ? 295 PRO C CG  1 
ATOM   9807  C CD  . PRO C 1 295 ? 124.112 124.744 147.632 1.00 24.48  ? 295 PRO C CD  1 
ATOM   9808  N N   . PHE C 1 296 ? 125.971 124.397 144.509 1.00 23.05  ? 296 PHE C N   1 
ATOM   9809  C CA  . PHE C 1 296 ? 127.058 124.039 143.610 1.00 23.05  ? 296 PHE C CA  1 
ATOM   9810  C C   . PHE C 1 296 ? 126.823 122.645 143.043 1.00 23.05  ? 296 PHE C C   1 
ATOM   9811  O O   . PHE C 1 296 ? 126.139 121.814 143.644 1.00 23.05  ? 296 PHE C O   1 
ATOM   9812  C CB  . PHE C 1 296 ? 128.418 124.091 144.319 1.00 23.05  ? 296 PHE C CB  1 
ATOM   9813  C CG  . PHE C 1 296 ? 128.688 125.391 145.020 1.00 23.05  ? 296 PHE C CG  1 
ATOM   9814  C CD1 . PHE C 1 296 ? 128.921 126.547 144.297 1.00 23.05  ? 296 PHE C CD1 1 
ATOM   9815  C CD2 . PHE C 1 296 ? 128.708 125.455 146.402 1.00 23.05  ? 296 PHE C CD2 1 
ATOM   9816  C CE1 . PHE C 1 296 ? 129.168 127.743 144.939 1.00 23.05  ? 296 PHE C CE1 1 
ATOM   9817  C CE2 . PHE C 1 296 ? 128.953 126.649 147.050 1.00 23.05  ? 296 PHE C CE2 1 
ATOM   9818  C CZ  . PHE C 1 296 ? 129.184 127.793 146.317 1.00 23.05  ? 296 PHE C CZ  1 
ATOM   9819  N N   . GLN C 1 297 ? 127.406 122.399 141.871 1.00 22.44  ? 297 GLN C N   1 
ATOM   9820  C CA  . GLN C 1 297 ? 127.293 121.109 141.207 1.00 22.44  ? 297 GLN C CA  1 
ATOM   9821  C C   . GLN C 1 297 ? 128.626 120.748 140.566 1.00 22.44  ? 297 GLN C C   1 
ATOM   9822  O O   . GLN C 1 297 ? 129.478 121.605 140.324 1.00 22.44  ? 297 GLN C O   1 
ATOM   9823  C CB  . GLN C 1 297 ? 126.170 121.104 140.157 1.00 22.44  ? 297 GLN C CB  1 
ATOM   9824  C CG  . GLN C 1 297 ? 126.308 122.150 139.062 1.00 22.44  ? 297 GLN C CG  1 
ATOM   9825  C CD  . GLN C 1 297 ? 126.764 121.561 137.744 1.00 22.44  ? 297 GLN C CD  1 
ATOM   9826  O OE1 . GLN C 1 297 ? 126.611 120.367 137.501 1.00 22.44  ? 297 GLN C OE1 1 
ATOM   9827  N NE2 . GLN C 1 297 ? 127.319 122.400 136.881 1.00 22.44  ? 297 GLN C NE2 1 
ATOM   9828  N N   . ASN C 1 298 ? 128.796 119.452 140.298 1.00 23.29  ? 298 ASN C N   1 
ATOM   9829  C CA  . ASN C 1 298 ? 130.036 118.918 139.750 1.00 23.29  ? 298 ASN C CA  1 
ATOM   9830  C C   . ASN C 1 298 ? 129.796 117.999 138.556 1.00 23.29  ? 298 ASN C C   1 
ATOM   9831  O O   . ASN C 1 298 ? 130.716 117.285 138.143 1.00 23.29  ? 298 ASN C O   1 
ATOM   9832  C CB  . ASN C 1 298 ? 130.813 118.170 140.842 1.00 23.29  ? 298 ASN C CB  1 
ATOM   9833  C CG  . ASN C 1 298 ? 132.271 117.965 140.493 1.00 23.29  ? 298 ASN C CG  1 
ATOM   9834  O OD1 . ASN C 1 298 ? 132.883 118.792 139.820 1.00 23.29  ? 298 ASN C OD1 1 
ATOM   9835  N ND2 . ASN C 1 298 ? 132.837 116.857 140.951 1.00 23.29  ? 298 ASN C ND2 1 
ATOM   9836  N N   . VAL C 1 299 ? 128.592 118.003 137.986 1.00 24.13  ? 299 VAL C N   1 
ATOM   9837  C CA  . VAL C 1 299 ? 128.257 117.032 136.949 1.00 24.13  ? 299 VAL C CA  1 
ATOM   9838  C C   . VAL C 1 299 ? 128.788 117.480 135.592 1.00 24.13  ? 299 VAL C C   1 
ATOM   9839  O O   . VAL C 1 299 ? 129.574 116.771 134.953 1.00 24.13  ? 299 VAL C O   1 
ATOM   9840  C CB  . VAL C 1 299 ? 126.736 116.799 136.914 1.00 24.13  ? 299 VAL C CB  1 
ATOM   9841  C CG1 . VAL C 1 299 ? 126.390 115.695 135.934 1.00 24.13  ? 299 VAL C CG1 1 
ATOM   9842  C CG2 . VAL C 1 299 ? 126.223 116.463 138.303 1.00 24.13  ? 299 VAL C CG2 1 
ATOM   9843  N N   . ASN C 1 300 ? 128.374 118.658 135.133 1.00 23.43  ? 300 ASN C N   1 
ATOM   9844  C CA  . ASN C 1 300 ? 128.765 119.149 133.821 1.00 23.43  ? 300 ASN C CA  1 
ATOM   9845  C C   . ASN C 1 300 ? 128.797 120.669 133.844 1.00 23.43  ? 300 ASN C C   1 
ATOM   9846  O O   . ASN C 1 300 ? 128.016 121.308 134.553 1.00 23.43  ? 300 ASN C O   1 
ATOM   9847  C CB  . ASN C 1 300 ? 127.802 118.658 132.732 1.00 23.43  ? 300 ASN C CB  1 
ATOM   9848  C CG  . ASN C 1 300 ? 128.511 118.283 131.446 1.00 23.43  ? 300 ASN C CG  1 
ATOM   9849  O OD1 . ASN C 1 300 ? 129.298 119.058 130.908 1.00 23.43  ? 300 ASN C OD1 1 
ATOM   9850  N ND2 . ASN C 1 300 ? 128.232 117.088 130.946 1.00 23.43  ? 300 ASN C ND2 1 
ATOM   9851  N N   . LYS C 1 301 ? 129.711 121.243 133.062 1.00 23.82  ? 301 LYS C N   1 
ATOM   9852  C CA  . LYS C 1 301 ? 129.751 122.691 132.904 1.00 23.82  ? 301 LYS C CA  1 
ATOM   9853  C C   . LYS C 1 301 ? 128.805 123.188 131.820 1.00 23.82  ? 301 LYS C C   1 
ATOM   9854  O O   . LYS C 1 301 ? 128.657 124.404 131.660 1.00 23.82  ? 301 LYS C O   1 
ATOM   9855  C CB  . LYS C 1 301 ? 131.180 123.155 132.606 1.00 23.82  ? 301 LYS C CB  1 
ATOM   9856  C CG  . LYS C 1 301 ? 131.766 122.619 131.319 1.00 23.82  ? 301 LYS C CG  1 
ATOM   9857  C CD  . LYS C 1 301 ? 133.249 122.938 131.230 1.00 23.82  ? 301 LYS C CD  1 
ATOM   9858  C CE  . LYS C 1 301 ? 133.789 122.677 129.834 1.00 23.82  ? 301 LYS C CE  1 
ATOM   9859  N NZ  . LYS C 1 301 ? 134.535 121.391 129.751 1.00 23.82  ? 301 LYS C NZ  1 
ATOM   9860  N N   . ILE C 1 302 ? 128.165 122.284 131.085 1.00 24.41  ? 302 ILE C N   1 
ATOM   9861  C CA  . ILE C 1 302 ? 127.133 122.627 130.115 1.00 24.41  ? 302 ILE C CA  1 
ATOM   9862  C C   . ILE C 1 302 ? 125.784 122.420 130.787 1.00 24.41  ? 302 ILE C C   1 
ATOM   9863  O O   . ILE C 1 302 ? 125.447 121.300 131.186 1.00 24.41  ? 302 ILE C O   1 
ATOM   9864  C CB  . ILE C 1 302 ? 127.257 121.776 128.842 1.00 24.41  ? 302 ILE C CB  1 
ATOM   9865  C CG1 . ILE C 1 302 ? 128.569 122.086 128.119 1.00 24.41  ? 302 ILE C CG1 1 
ATOM   9866  C CG2 . ILE C 1 302 ? 126.071 122.012 127.924 1.00 24.41  ? 302 ILE C CG2 1 
ATOM   9867  C CD1 . ILE C 1 302 ? 129.160 120.903 127.392 1.00 24.41  ? 302 ILE C CD1 1 
ATOM   9868  N N   . THR C 1 303 ? 125.010 123.496 130.918 1.00 26.68  ? 303 THR C N   1 
ATOM   9869  C CA  . THR C 1 303 ? 123.757 123.462 131.658 1.00 26.68  ? 303 THR C CA  1 
ATOM   9870  C C   . THR C 1 303 ? 122.710 124.296 130.935 1.00 26.68  ? 303 THR C C   1 
ATOM   9871  O O   . THR C 1 303 ? 123.029 125.199 130.159 1.00 26.68  ? 303 THR C O   1 
ATOM   9872  C CB  . THR C 1 303 ? 123.931 123.983 133.094 1.00 26.68  ? 303 THR C CB  1 
ATOM   9873  O OG1 . THR C 1 303 ? 124.721 125.178 133.079 1.00 26.68  ? 303 THR C OG1 1 
ATOM   9874  C CG2 . THR C 1 303 ? 124.615 122.944 133.969 1.00 26.68  ? 303 THR C CG2 1 
ATOM   9875  N N   . TYR C 1 304 ? 121.444 123.979 131.205 1.00 24.43  ? 304 TYR C N   1 
ATOM   9876  C CA  . TYR C 1 304 ? 120.315 124.745 130.694 1.00 24.43  ? 304 TYR C CA  1 
ATOM   9877  C C   . TYR C 1 304 ? 119.253 124.838 131.778 1.00 24.43  ? 304 TYR C C   1 
ATOM   9878  O O   . TYR C 1 304 ? 118.878 123.822 132.368 1.00 24.43  ? 304 TYR C O   1 
ATOM   9879  C CB  . TYR C 1 304 ? 119.728 124.106 129.429 1.00 24.43  ? 304 TYR C CB  1 
ATOM   9880  C CG  . TYR C 1 304 ? 118.547 124.860 128.858 1.00 24.43  ? 304 TYR C CG  1 
ATOM   9881  C CD1 . TYR C 1 304 ? 118.735 125.943 128.014 1.00 24.43  ? 304 TYR C CD1 1 
ATOM   9882  C CD2 . TYR C 1 304 ? 117.246 124.486 129.163 1.00 24.43  ? 304 TYR C CD2 1 
ATOM   9883  C CE1 . TYR C 1 304 ? 117.662 126.636 127.493 1.00 24.43  ? 304 TYR C CE1 1 
ATOM   9884  C CE2 . TYR C 1 304 ? 116.167 125.172 128.646 1.00 24.43  ? 304 TYR C CE2 1 
ATOM   9885  C CZ  . TYR C 1 304 ? 116.381 126.246 127.812 1.00 24.43  ? 304 TYR C CZ  1 
ATOM   9886  O OH  . TYR C 1 304 ? 115.310 126.934 127.294 1.00 24.43  ? 304 TYR C OH  1 
ATOM   9887  N N   . GLY C 1 305 ? 118.775 126.047 132.034 1.00 28.30  ? 305 GLY C N   1 
ATOM   9888  C CA  . GLY C 1 305 ? 117.748 126.286 133.023 1.00 28.30  ? 305 GLY C CA  1 
ATOM   9889  C C   . GLY C 1 305 ? 118.300 126.890 134.299 1.00 28.30  ? 305 GLY C C   1 
ATOM   9890  O O   . GLY C 1 305 ? 119.362 127.517 134.324 1.00 28.30  ? 305 GLY C O   1 
ATOM   9891  N N   . ALA C 1 306 ? 117.551 126.694 135.382 1.00 31.50  ? 306 ALA C N   1 
ATOM   9892  C CA  . ALA C 1 306 ? 117.960 127.147 136.710 1.00 31.50  ? 306 ALA C CA  1 
ATOM   9893  C C   . ALA C 1 306 ? 118.837 126.062 137.320 1.00 31.50  ? 306 ALA C C   1 
ATOM   9894  O O   . ALA C 1 306 ? 118.338 125.053 137.823 1.00 31.50  ? 306 ALA C O   1 
ATOM   9895  C CB  . ALA C 1 306 ? 116.745 127.445 137.580 1.00 31.50  ? 306 ALA C CB  1 
ATOM   9896  N N   . CYS C 1 307 ? 120.148 126.271 137.281 1.00 31.78  ? 307 CYS C N   1 
ATOM   9897  C CA  . CYS C 1 307 ? 121.111 125.242 137.633 1.00 31.78  ? 307 CYS C CA  1 
ATOM   9898  C C   . CYS C 1 307 ? 122.106 125.767 138.655 1.00 31.78  ? 307 CYS C C   1 
ATOM   9899  O O   . CYS C 1 307 ? 122.350 126.975 138.727 1.00 31.78  ? 307 CYS C O   1 
ATOM   9900  C CB  . CYS C 1 307 ? 121.872 124.760 136.389 1.00 31.78  ? 307 CYS C CB  1 
ATOM   9901  S SG  . CYS C 1 307 ? 120.863 123.876 135.183 1.00 31.78  ? 307 CYS C SG  1 
ATOM   9902  N N   . PRO C 1 308 ? 122.690 124.884 139.460 1.00 25.94  ? 308 PRO C N   1 
ATOM   9903  C CA  . PRO C 1 308 ? 123.763 125.308 140.363 1.00 25.94  ? 308 PRO C CA  1 
ATOM   9904  C C   . PRO C 1 308 ? 125.033 125.642 139.596 1.00 25.94  ? 308 PRO C C   1 
ATOM   9905  O O   . PRO C 1 308 ? 125.187 125.323 138.415 1.00 25.94  ? 308 PRO C O   1 
ATOM   9906  C CB  . PRO C 1 308 ? 123.970 124.092 141.275 1.00 25.94  ? 308 PRO C CB  1 
ATOM   9907  C CG  . PRO C 1 308 ? 122.749 123.251 141.100 1.00 25.94  ? 308 PRO C CG  1 
ATOM   9908  C CD  . PRO C 1 308 ? 122.276 123.494 139.708 1.00 25.94  ? 308 PRO C CD  1 
ATOM   9909  N N   . LYS C 1 309 ? 125.953 126.301 140.293 1.00 22.94  ? 309 LYS C N   1 
ATOM   9910  C CA  . LYS C 1 309 ? 127.207 126.721 139.687 1.00 22.94  ? 309 LYS C CA  1 
ATOM   9911  C C   . LYS C 1 309 ? 128.206 125.572 139.665 1.00 22.94  ? 309 LYS C C   1 
ATOM   9912  O O   . LYS C 1 309 ? 128.284 124.777 140.605 1.00 22.94  ? 309 LYS C O   1 
ATOM   9913  C CB  . LYS C 1 309 ? 127.790 127.911 140.447 1.00 22.94  ? 309 LYS C CB  1 
ATOM   9914  C CG  . LYS C 1 309 ? 126.849 129.095 140.530 1.00 22.94  ? 309 LYS C CG  1 
ATOM   9915  C CD  . LYS C 1 309 ? 127.535 130.308 141.120 1.00 22.94  ? 309 LYS C CD  1 
ATOM   9916  C CE  . LYS C 1 309 ? 126.594 131.498 141.173 1.00 22.94  ? 309 LYS C CE  1 
ATOM   9917  N NZ  . LYS C 1 309 ? 125.596 131.371 142.268 1.00 22.94  ? 309 LYS C NZ  1 
ATOM   9918  N N   . TYR C 1 310 ? 128.976 125.491 138.583 1.00 21.10  ? 310 TYR C N   1 
ATOM   9919  C CA  . TYR C 1 310 ? 129.924 124.401 138.405 1.00 21.10  ? 310 TYR C CA  1 
ATOM   9920  C C   . TYR C 1 310 ? 131.232 124.713 139.121 1.00 21.10  ? 310 TYR C C   1 
ATOM   9921  O O   . TYR C 1 310 ? 131.810 125.789 138.941 1.00 21.10  ? 310 TYR C O   1 
ATOM   9922  C CB  . TYR C 1 310 ? 130.181 124.152 136.920 1.00 21.10  ? 310 TYR C CB  1 
ATOM   9923  C CG  . TYR C 1 310 ? 131.179 123.049 136.655 1.00 21.10  ? 310 TYR C CG  1 
ATOM   9924  C CD1 . TYR C 1 310 ? 130.827 121.717 136.816 1.00 21.10  ? 310 TYR C CD1 1 
ATOM   9925  C CD2 . TYR C 1 310 ? 132.473 123.338 136.247 1.00 21.10  ? 310 TYR C CD2 1 
ATOM   9926  C CE1 . TYR C 1 310 ? 131.732 120.706 136.578 1.00 21.10  ? 310 TYR C CE1 1 
ATOM   9927  C CE2 . TYR C 1 310 ? 133.386 122.332 136.007 1.00 21.10  ? 310 TYR C CE2 1 
ATOM   9928  C CZ  . TYR C 1 310 ? 133.009 121.018 136.174 1.00 21.10  ? 310 TYR C CZ  1 
ATOM   9929  O OH  . TYR C 1 310 ? 133.913 120.011 135.938 1.00 21.10  ? 310 TYR C OH  1 
ATOM   9930  N N   . VAL C 1 311 ? 131.698 123.763 139.932 1.00 21.48  ? 311 VAL C N   1 
ATOM   9931  C CA  . VAL C 1 311 ? 132.953 123.885 140.657 1.00 21.48  ? 311 VAL C CA  1 
ATOM   9932  C C   . VAL C 1 311 ? 133.750 122.603 140.460 1.00 21.48  ? 311 VAL C C   1 
ATOM   9933  O O   . VAL C 1 311 ? 133.207 121.553 140.114 1.00 21.48  ? 311 VAL C O   1 
ATOM   9934  C CB  . VAL C 1 311 ? 132.740 124.164 142.162 1.00 21.48  ? 311 VAL C CB  1 
ATOM   9935  C CG1 . VAL C 1 311 ? 132.108 125.529 142.367 1.00 21.48  ? 311 VAL C CG1 1 
ATOM   9936  C CG2 . VAL C 1 311 ? 131.884 123.077 142.791 1.00 21.48  ? 311 VAL C CG2 1 
ATOM   9937  N N   . LYS C 1 312 ? 135.060 122.705 140.682 1.00 23.10  ? 312 LYS C N   1 
ATOM   9938  C CA  . LYS C 1 312 ? 135.940 121.553 140.532 1.00 23.10  ? 312 LYS C CA  1 
ATOM   9939  C C   . LYS C 1 312 ? 135.932 120.640 141.751 1.00 23.10  ? 312 LYS C C   1 
ATOM   9940  O O   . LYS C 1 312 ? 136.410 119.505 141.658 1.00 23.10  ? 312 LYS C O   1 
ATOM   9941  C CB  . LYS C 1 312 ? 137.371 122.015 140.255 1.00 23.10  ? 312 LYS C CB  1 
ATOM   9942  C CG  . LYS C 1 312 ? 137.572 122.638 138.887 1.00 23.10  ? 312 LYS C CG  1 
ATOM   9943  C CD  . LYS C 1 312 ? 139.024 123.022 138.674 1.00 23.10  ? 312 LYS C CD  1 
ATOM   9944  C CE  . LYS C 1 312 ? 139.385 124.263 139.470 1.00 23.10  ? 312 LYS C CE  1 
ATOM   9945  N NZ  . LYS C 1 312 ? 140.806 124.654 139.276 1.00 23.10  ? 312 LYS C NZ  1 
ATOM   9946  N N   . GLN C 1 313 ? 135.405 121.102 142.881 1.00 23.96  ? 313 GLN C N   1 
ATOM   9947  C CA  . GLN C 1 313 ? 135.427 120.304 144.098 1.00 23.96  ? 313 GLN C CA  1 
ATOM   9948  C C   . GLN C 1 313 ? 134.370 119.210 144.048 1.00 23.96  ? 313 GLN C C   1 
ATOM   9949  O O   . GLN C 1 313 ? 133.251 119.423 143.574 1.00 23.96  ? 313 GLN C O   1 
ATOM   9950  C CB  . GLN C 1 313 ? 135.202 121.192 145.320 1.00 23.96  ? 313 GLN C CB  1 
ATOM   9951  C CG  . GLN C 1 313 ? 136.386 122.073 145.671 1.00 23.96  ? 313 GLN C CG  1 
ATOM   9952  C CD  . GLN C 1 313 ? 136.200 123.503 145.215 1.00 23.96  ? 313 GLN C CD  1 
ATOM   9953  O OE1 . GLN C 1 313 ? 135.991 123.766 144.033 1.00 23.96  ? 313 GLN C OE1 1 
ATOM   9954  N NE2 . GLN C 1 313 ? 136.276 124.437 146.152 1.00 23.96  ? 313 GLN C NE2 1 
ATOM   9955  N N   . ASN C 1 314 ? 134.734 118.030 144.545 1.00 27.43  ? 314 ASN C N   1 
ATOM   9956  C CA  . ASN C 1 314 ? 133.815 116.902 144.598 1.00 27.43  ? 314 ASN C CA  1 
ATOM   9957  C C   . ASN C 1 314 ? 132.864 116.999 145.784 1.00 27.43  ? 314 ASN C C   1 
ATOM   9958  O O   . ASN C 1 314 ? 131.712 116.563 145.684 1.00 27.43  ? 314 ASN C O   1 
ATOM   9959  C CB  . ASN C 1 314 ? 134.614 115.594 144.664 1.00 27.43  ? 314 ASN C CB  1 
ATOM   9960  C CG  . ASN C 1 314 ? 133.748 114.351 144.504 1.00 27.43  ? 314 ASN C CG  1 
ATOM   9961  O OD1 . ASN C 1 314 ? 132.529 114.429 144.363 1.00 27.43  ? 314 ASN C OD1 1 
ATOM   9962  N ND2 . ASN C 1 314 ? 134.389 113.188 144.533 1.00 27.43  ? 314 ASN C ND2 1 
ATOM   9963  N N   . THR C 1 315 ? 133.304 117.590 146.894 1.00 28.35  ? 315 THR C N   1 
ATOM   9964  C CA  . THR C 1 315 ? 132.475 117.681 148.086 1.00 28.35  ? 315 THR C CA  1 
ATOM   9965  C C   . THR C 1 315 ? 132.848 118.926 148.879 1.00 28.35  ? 315 THR C C   1 
ATOM   9966  O O   . THR C 1 315 ? 134.003 119.361 148.876 1.00 28.35  ? 315 THR C O   1 
ATOM   9967  C CB  . THR C 1 315 ? 132.610 116.425 148.960 1.00 28.35  ? 315 THR C CB  1 
ATOM   9968  O OG1 . THR C 1 315 ? 131.701 116.504 150.065 1.00 28.35  ? 315 THR C OG1 1 
ATOM   9969  C CG2 . THR C 1 315 ? 134.030 116.274 149.484 1.00 28.35  ? 315 THR C CG2 1 
ATOM   9970  N N   . LEU C 1 316 ? 131.848 119.500 149.547 1.00 28.52  ? 316 LEU C N   1 
ATOM   9971  C CA  . LEU C 1 316 ? 132.040 120.668 150.406 1.00 28.52  ? 316 LEU C CA  1 
ATOM   9972  C C   . LEU C 1 316 ? 131.021 120.575 151.532 1.00 28.52  ? 316 LEU C C   1 
ATOM   9973  O O   . LEU C 1 316 ? 129.818 120.695 151.287 1.00 28.52  ? 316 LEU C O   1 
ATOM   9974  C CB  . LEU C 1 316 ? 131.873 121.971 149.626 1.00 28.52  ? 316 LEU C CB  1 
ATOM   9975  C CG  . LEU C 1 316 ? 133.038 122.454 148.758 1.00 28.52  ? 316 LEU C CG  1 
ATOM   9976  C CD1 . LEU C 1 316 ? 132.582 123.555 147.815 1.00 28.52  ? 316 LEU C CD1 1 
ATOM   9977  C CD2 . LEU C 1 316 ? 134.200 122.928 149.614 1.00 28.52  ? 316 LEU C CD2 1 
ATOM   9978  N N   . LYS C 1 317 ? 131.496 120.369 152.757 1.00 30.71  ? 317 LYS C N   1 
ATOM   9979  C CA  . LYS C 1 317 ? 130.628 120.173 153.911 1.00 30.71  ? 317 LYS C CA  1 
ATOM   9980  C C   . LYS C 1 317 ? 130.477 121.479 154.680 1.00 30.71  ? 317 LYS C C   1 
ATOM   9981  O O   . LYS C 1 317 ? 131.473 122.138 154.997 1.00 30.71  ? 317 LYS C O   1 
ATOM   9982  C CB  . LYS C 1 317 ? 131.183 119.083 154.830 1.00 30.71  ? 317 LYS C CB  1 
ATOM   9983  C CG  . LYS C 1 317 ? 131.396 117.742 154.150 1.00 30.71  ? 317 LYS C CG  1 
ATOM   9984  C CD  . LYS C 1 317 ? 130.099 117.202 153.575 1.00 30.71  ? 317 LYS C CD  1 
ATOM   9985  C CE  . LYS C 1 317 ? 129.157 116.738 154.671 1.00 30.71  ? 317 LYS C CE  1 
ATOM   9986  N NZ  . LYS C 1 317 ? 129.665 115.524 155.365 1.00 30.71  ? 317 LYS C NZ  1 
ATOM   9987  N N   . LEU C 1 318 ? 129.235 121.844 154.979 1.00 32.15  ? 318 LEU C N   1 
ATOM   9988  C CA  . LEU C 1 318 ? 128.919 123.041 155.745 1.00 32.15  ? 318 LEU C CA  1 
ATOM   9989  C C   . LEU C 1 318 ? 128.462 122.634 157.138 1.00 32.15  ? 318 LEU C C   1 
ATOM   9990  O O   . LEU C 1 318 ? 127.569 121.793 157.280 1.00 32.15  ? 318 LEU C O   1 
ATOM   9991  C CB  . LEU C 1 318 ? 127.835 123.866 155.049 1.00 32.15  ? 318 LEU C CB  1 
ATOM   9992  C CG  . LEU C 1 318 ? 127.522 125.240 155.643 1.00 32.15  ? 318 LEU C CG  1 
ATOM   9993  C CD1 . LEU C 1 318 ? 128.494 126.283 155.121 1.00 32.15  ? 318 LEU C CD1 1 
ATOM   9994  C CD2 . LEU C 1 318 ? 126.090 125.641 155.341 1.00 32.15  ? 318 LEU C CD2 1 
ATOM   9995  N N   . ALA C 1 319 ? 129.070 123.232 158.159 1.00 37.03  ? 319 ALA C N   1 
ATOM   9996  C CA  . ALA C 1 319 ? 128.744 122.880 159.534 1.00 37.03  ? 319 ALA C CA  1 
ATOM   9997  C C   . ALA C 1 319 ? 127.358 123.387 159.909 1.00 37.03  ? 319 ALA C C   1 
ATOM   9998  O O   . ALA C 1 319 ? 126.967 124.502 159.553 1.00 37.03  ? 319 ALA C O   1 
ATOM   9999  C CB  . ALA C 1 319 ? 129.788 123.451 160.492 1.00 37.03  ? 319 ALA C CB  1 
ATOM   10000 N N   . THR C 1 320 ? 126.617 122.560 160.640 1.00 42.62  ? 320 THR C N   1 
ATOM   10001 C CA  . THR C 1 320 ? 125.275 122.897 161.092 1.00 42.62  ? 320 THR C CA  1 
ATOM   10002 C C   . THR C 1 320 ? 125.131 122.895 162.607 1.00 42.62  ? 320 THR C C   1 
ATOM   10003 O O   . THR C 1 320 ? 124.373 123.707 163.141 1.00 42.62  ? 320 THR C O   1 
ATOM   10004 C CB  . THR C 1 320 ? 124.252 121.924 160.472 1.00 42.62  ? 320 THR C CB  1 
ATOM   10005 O OG1 . THR C 1 320 ? 124.100 122.216 159.078 1.00 42.62  ? 320 THR C OG1 1 
ATOM   10006 C CG2 . THR C 1 320 ? 122.893 122.036 161.145 1.00 42.62  ? 320 THR C CG2 1 
ATOM   10007 N N   . GLY C 1 321 ? 125.868 122.040 163.318 1.00 42.69  ? 321 GLY C N   1 
ATOM   10008 C CA  . GLY C 1 321 ? 125.823 121.980 164.754 1.00 42.69  ? 321 GLY C CA  1 
ATOM   10009 C C   . GLY C 1 321 ? 127.058 122.567 165.406 1.00 42.69  ? 321 GLY C C   1 
ATOM   10010 O O   . GLY C 1 321 ? 127.794 123.366 164.812 1.00 42.69  ? 321 GLY C O   1 
ATOM   10011 N N   . MET C 1 322 ? 127.289 122.164 166.653 1.00 46.28  ? 322 MET C N   1 
ATOM   10012 C CA  . MET C 1 322 ? 128.431 122.632 167.418 1.00 46.28  ? 322 MET C CA  1 
ATOM   10013 C C   . MET C 1 322 ? 129.555 121.601 167.382 1.00 46.28  ? 322 MET C C   1 
ATOM   10014 O O   . MET C 1 322 ? 129.451 120.550 166.748 1.00 46.28  ? 322 MET C O   1 
ATOM   10015 C CB  . MET C 1 322 ? 128.027 122.931 168.859 1.00 46.28  ? 322 MET C CB  1 
ATOM   10016 C CG  . MET C 1 322 ? 127.479 121.744 169.623 1.00 46.28  ? 322 MET C CG  1 
ATOM   10017 S SD  . MET C 1 322 ? 127.003 122.184 171.304 1.00 46.28  ? 322 MET C SD  1 
ATOM   10018 C CE  . MET C 1 322 ? 125.503 123.109 170.999 1.00 46.28  ? 322 MET C CE  1 
ATOM   10019 N N   . ARG C 1 323 ? 130.646 121.906 168.080 1.00 48.12  ? 323 ARG C N   1 
ATOM   10020 C CA  . ARG C 1 323 ? 131.758 120.972 168.175 1.00 48.12  ? 323 ARG C CA  1 
ATOM   10021 C C   . ARG C 1 323 ? 131.342 119.732 168.952 1.00 48.12  ? 323 ARG C C   1 
ATOM   10022 O O   . ARG C 1 323 ? 130.644 119.818 169.966 1.00 48.12  ? 323 ARG C O   1 
ATOM   10023 C CB  . ARG C 1 323 ? 132.955 121.635 168.853 1.00 48.12  ? 323 ARG C CB  1 
ATOM   10024 C CG  . ARG C 1 323 ? 133.181 123.078 168.446 1.00 48.12  ? 323 ARG C CG  1 
ATOM   10025 C CD  . ARG C 1 323 ? 134.215 123.744 169.338 1.00 48.12  ? 323 ARG C CD  1 
ATOM   10026 N NE  . ARG C 1 323 ? 135.540 123.159 169.173 1.00 48.12  ? 323 ARG C NE  1 
ATOM   10027 C CZ  . ARG C 1 323 ? 136.665 123.858 169.120 1.00 48.12  ? 323 ARG C CZ  1 
ATOM   10028 N NH1 . ARG C 1 323 ? 136.663 125.177 169.219 1.00 48.12  ? 323 ARG C NH1 1 
ATOM   10029 N NH2 . ARG C 1 323 ? 137.820 123.219 168.961 1.00 48.12  ? 323 ARG C NH2 1 
ATOM   10030 N N   . ASN C 1 324 ? 131.775 118.570 168.472 1.00 51.93  ? 324 ASN C N   1 
ATOM   10031 C CA  . ASN C 1 324 ? 131.475 117.300 169.122 1.00 51.93  ? 324 ASN C CA  1 
ATOM   10032 C C   . ASN C 1 324 ? 132.608 116.975 170.089 1.00 51.93  ? 324 ASN C C   1 
ATOM   10033 O O   . ASN C 1 324 ? 133.739 116.714 169.668 1.00 51.93  ? 324 ASN C O   1 
ATOM   10034 C CB  . ASN C 1 324 ? 131.292 116.193 168.088 1.00 51.93  ? 324 ASN C CB  1 
ATOM   10035 C CG  . ASN C 1 324 ? 130.325 115.123 168.548 1.00 51.93  ? 324 ASN C CG  1 
ATOM   10036 O OD1 . ASN C 1 324 ? 129.238 115.423 169.040 1.00 51.93  ? 324 ASN C OD1 1 
ATOM   10037 N ND2 . ASN C 1 324 ? 130.714 113.865 168.388 1.00 51.93  ? 324 ASN C ND2 1 
ATOM   10038 N N   . VAL C 1 325 ? 132.304 116.996 171.382 1.00 58.34  ? 325 VAL C N   1 
ATOM   10039 C CA  . VAL C 1 325 ? 133.269 116.719 172.437 1.00 58.34  ? 325 VAL C CA  1 
ATOM   10040 C C   . VAL C 1 325 ? 132.788 115.486 173.189 1.00 58.34  ? 325 VAL C C   1 
ATOM   10041 O O   . VAL C 1 325 ? 131.656 115.475 173.674 1.00 58.34  ? 325 VAL C O   1 
ATOM   10042 C CB  . VAL C 1 325 ? 133.440 117.903 173.405 1.00 58.34  ? 325 VAL C CB  1 
ATOM   10043 C CG1 . VAL C 1 325 ? 134.672 117.712 174.270 1.00 58.34  ? 325 VAL C CG1 1 
ATOM   10044 C CG2 . VAL C 1 325 ? 133.524 119.211 172.634 1.00 58.34  ? 325 VAL C CG2 1 
ATOM   10045 N N   . PRO C 1 326 ? 133.596 114.435 173.305 1.00 62.71  ? 326 PRO C N   1 
ATOM   10046 C CA  . PRO C 1 326 ? 133.142 113.240 174.022 1.00 62.71  ? 326 PRO C CA  1 
ATOM   10047 C C   . PRO C 1 326 ? 133.051 113.484 175.520 1.00 62.71  ? 326 PRO C C   1 
ATOM   10048 O O   . PRO C 1 326 ? 133.770 114.309 176.088 1.00 62.71  ? 326 PRO C O   1 
ATOM   10049 C CB  . PRO C 1 326 ? 134.208 112.188 173.689 1.00 62.71  ? 326 PRO C CB  1 
ATOM   10050 C CG  . PRO C 1 326 ? 135.351 112.926 173.049 1.00 62.71  ? 326 PRO C CG  1 
ATOM   10051 C CD  . PRO C 1 326 ? 135.030 114.384 172.982 1.00 62.71  ? 326 PRO C CD  1 
ATOM   10052 N N   . GLU C 1 327 ? 132.147 112.746 176.158 1.00 65.67  ? 327 GLU C N   1 
ATOM   10053 C CA  . GLU C 1 327 ? 131.914 112.882 177.591 1.00 65.67  ? 327 GLU C CA  1 
ATOM   10054 C C   . GLU C 1 327 ? 133.089 112.341 178.400 1.00 65.67  ? 327 GLU C C   1 
ATOM   10055 O O   . GLU C 1 327 ? 133.450 111.170 178.283 1.00 65.67  ? 327 GLU C O   1 
ATOM   10056 C CB  . GLU C 1 327 ? 130.624 112.161 177.989 1.00 65.67  ? 327 GLU C CB  1 
ATOM   10057 C CG  . GLU C 1 327 ? 130.104 112.530 179.367 1.00 65.67  ? 327 GLU C CG  1 
ATOM   10058 C CD  . GLU C 1 327 ? 128.605 112.338 179.494 1.00 65.67  ? 327 GLU C CD  1 
ATOM   10059 O OE1 . GLU C 1 327 ? 128.058 111.449 178.807 1.00 65.67  ? 327 GLU C OE1 1 
ATOM   10060 O OE2 . GLU C 1 327 ? 127.973 113.076 180.278 1.00 65.67  ? 327 GLU C OE2 1 
ATOM   10061 N N   . ILE C 1 337 ? 129.131 115.439 189.153 1.00 74.39  ? 337 ILE C N   1 
ATOM   10062 C CA  . ILE C 1 337 ? 128.783 115.928 187.826 1.00 74.39  ? 337 ILE C CA  1 
ATOM   10063 C C   . ILE C 1 337 ? 129.809 116.956 187.360 1.00 74.39  ? 337 ILE C C   1 
ATOM   10064 O O   . ILE C 1 337 ? 130.512 117.556 188.172 1.00 74.39  ? 337 ILE C O   1 
ATOM   10065 C CB  . ILE C 1 337 ? 127.360 116.512 187.807 1.00 74.39  ? 337 ILE C CB  1 
ATOM   10066 C CG1 . ILE C 1 337 ? 127.162 117.484 188.971 1.00 74.39  ? 337 ILE C CG1 1 
ATOM   10067 C CG2 . ILE C 1 337 ? 126.326 115.399 187.863 1.00 74.39  ? 337 ILE C CG2 1 
ATOM   10068 C CD1 . ILE C 1 337 ? 125.812 118.169 188.970 1.00 74.39  ? 337 ILE C CD1 1 
ATOM   10069 N N   . ALA C 1 338 ? 129.891 117.155 186.046 1.00 71.26  ? 338 ALA C N   1 
ATOM   10070 C CA  . ALA C 1 338 ? 130.871 118.047 185.446 1.00 71.26  ? 338 ALA C CA  1 
ATOM   10071 C C   . ALA C 1 338 ? 130.178 118.998 184.480 1.00 71.26  ? 338 ALA C C   1 
ATOM   10072 O O   . ALA C 1 338 ? 129.055 118.755 184.032 1.00 71.26  ? 338 ALA C O   1 
ATOM   10073 C CB  . ALA C 1 338 ? 131.972 117.266 184.718 1.00 71.26  ? 338 ALA C CB  1 
ATOM   10074 N N   . GLY C 1 339 ? 130.864 120.087 184.164 1.00 67.76  ? 339 GLY C N   1 
ATOM   10075 C CA  . GLY C 1 339 ? 130.335 121.146 183.333 1.00 67.76  ? 339 GLY C CA  1 
ATOM   10076 C C   . GLY C 1 339 ? 130.728 121.012 181.877 1.00 67.76  ? 339 GLY C C   1 
ATOM   10077 O O   . GLY C 1 339 ? 131.001 119.914 181.379 1.00 67.76  ? 339 GLY C O   1 
ATOM   10078 N N   . PHE C 1 340 ? 130.762 122.148 181.184 1.00 66.06  ? 340 PHE C N   1 
ATOM   10079 C CA  . PHE C 1 340 ? 131.014 122.189 179.750 1.00 66.06  ? 340 PHE C CA  1 
ATOM   10080 C C   . PHE C 1 340 ? 132.485 122.358 179.397 1.00 66.06  ? 340 PHE C C   1 
ATOM   10081 O O   . PHE C 1 340 ? 132.812 122.455 178.210 1.00 66.06  ? 340 PHE C O   1 
ATOM   10082 C CB  . PHE C 1 340 ? 130.202 123.320 179.106 1.00 66.06  ? 340 PHE C CB  1 
ATOM   10083 C CG  . PHE C 1 340 ? 130.648 124.698 179.512 1.00 66.06  ? 340 PHE C CG  1 
ATOM   10084 C CD1 . PHE C 1 340 ? 130.162 125.284 180.667 1.00 66.06  ? 340 PHE C CD1 1 
ATOM   10085 C CD2 . PHE C 1 340 ? 131.544 125.411 178.732 1.00 66.06  ? 340 PHE C CD2 1 
ATOM   10086 C CE1 . PHE C 1 340 ? 130.567 126.549 181.041 1.00 66.06  ? 340 PHE C CE1 1 
ATOM   10087 C CE2 . PHE C 1 340 ? 131.953 126.677 179.103 1.00 66.06  ? 340 PHE C CE2 1 
ATOM   10088 C CZ  . PHE C 1 340 ? 131.463 127.246 180.258 1.00 66.06  ? 340 PHE C CZ  1 
ATOM   10089 N N   . ILE C 1 341 ? 133.378 122.400 180.384 1.00 69.49  ? 341 ILE C N   1 
ATOM   10090 C CA  . ILE C 1 341 ? 134.803 122.590 180.123 1.00 69.49  ? 341 ILE C CA  1 
ATOM   10091 C C   . ILE C 1 341 ? 135.352 121.263 179.604 1.00 69.49  ? 341 ILE C C   1 
ATOM   10092 O O   . ILE C 1 341 ? 135.631 120.347 180.379 1.00 69.49  ? 341 ILE C O   1 
ATOM   10093 C CB  . ILE C 1 341 ? 135.556 123.068 181.366 1.00 69.49  ? 341 ILE C CB  1 
ATOM   10094 C CG1 . ILE C 1 341 ? 135.001 124.412 181.842 1.00 69.49  ? 341 ILE C CG1 1 
ATOM   10095 C CG2 . ILE C 1 341 ? 137.043 123.190 181.073 1.00 69.49  ? 341 ILE C CG2 1 
ATOM   10096 C CD1 . ILE C 1 341 ? 135.249 125.553 180.882 1.00 69.49  ? 341 ILE C CD1 1 
ATOM   10097 N N   . GLU C 1 342 ? 135.507 121.163 178.281 1.00 70.25  ? 342 GLU C N   1 
ATOM   10098 C CA  . GLU C 1 342 ? 136.029 119.963 177.623 1.00 70.25  ? 342 GLU C CA  1 
ATOM   10099 C C   . GLU C 1 342 ? 135.225 118.721 178.001 1.00 70.25  ? 342 GLU C C   1 
ATOM   10100 O O   . GLU C 1 342 ? 135.785 117.661 178.288 1.00 70.25  ? 342 GLU C O   1 
ATOM   10101 C CB  . GLU C 1 342 ? 137.514 119.765 177.934 1.00 70.25  ? 342 GLU C CB  1 
ATOM   10102 C CG  . GLU C 1 342 ? 138.428 120.794 177.288 1.00 70.25  ? 342 GLU C CG  1 
ATOM   10103 C CD  . GLU C 1 342 ? 138.468 120.675 175.776 1.00 70.25  ? 342 GLU C CD  1 
ATOM   10104 O OE1 . GLU C 1 342 ? 138.253 119.558 175.259 1.00 70.25  ? 342 GLU C OE1 1 
ATOM   10105 O OE2 . GLU C 1 342 ? 138.716 121.697 175.104 1.00 70.25  ? 342 GLU C OE2 1 
ATOM   10106 N N   . ASN C 1 343 ? 133.900 118.849 177.997 1.00 66.71  ? 343 ASN C N   1 
ATOM   10107 C CA  . ASN C 1 343 ? 133.030 117.737 178.372 1.00 66.71  ? 343 ASN C CA  1 
ATOM   10108 C C   . ASN C 1 343 ? 131.646 117.982 177.794 1.00 66.71  ? 343 ASN C C   1 
ATOM   10109 O O   . ASN C 1 343 ? 130.988 118.962 178.158 1.00 66.71  ? 343 ASN C O   1 
ATOM   10110 C CB  . ASN C 1 343 ? 132.965 117.588 179.893 1.00 66.71  ? 343 ASN C CB  1 
ATOM   10111 C CG  . ASN C 1 343 ? 131.932 116.573 180.336 1.00 66.71  ? 343 ASN C CG  1 
ATOM   10112 O OD1 . ASN C 1 343 ? 132.080 115.375 180.098 1.00 66.71  ? 343 ASN C OD1 1 
ATOM   10113 N ND2 . ASN C 1 343 ? 130.878 117.048 180.989 1.00 66.71  ? 343 ASN C ND2 1 
ATOM   10114 N N   . GLY C 1 344 ? 131.206 117.099 176.898 1.00 64.88  ? 344 GLY C N   1 
ATOM   10115 C CA  . GLY C 1 344 ? 129.871 117.158 176.350 1.00 64.88  ? 344 GLY C CA  1 
ATOM   10116 C C   . GLY C 1 344 ? 128.947 116.158 177.019 1.00 64.88  ? 344 GLY C C   1 
ATOM   10117 O O   . GLY C 1 344 ? 129.382 115.142 177.553 1.00 64.88  ? 344 GLY C O   1 
ATOM   10118 N N   . TRP C 1 345 ? 127.652 116.461 176.985 1.00 64.41  ? 345 TRP C N   1 
ATOM   10119 C CA  . TRP C 1 345 ? 126.637 115.643 177.641 1.00 64.41  ? 345 TRP C CA  1 
ATOM   10120 C C   . TRP C 1 345 ? 125.995 114.727 176.606 1.00 64.41  ? 345 TRP C C   1 
ATOM   10121 O O   . TRP C 1 345 ? 125.260 115.187 175.727 1.00 64.41  ? 345 TRP C O   1 
ATOM   10122 C CB  . TRP C 1 345 ? 125.590 116.521 178.324 1.00 64.41  ? 345 TRP C CB  1 
ATOM   10123 C CG  . TRP C 1 345 ? 126.109 117.226 179.536 1.00 64.41  ? 345 TRP C CG  1 
ATOM   10124 C CD1 . TRP C 1 345 ? 127.316 117.037 180.140 1.00 64.41  ? 345 TRP C CD1 1 
ATOM   10125 C CD2 . TRP C 1 345 ? 125.434 118.234 180.298 1.00 64.41  ? 345 TRP C CD2 1 
ATOM   10126 N NE1 . TRP C 1 345 ? 127.437 117.864 181.228 1.00 64.41  ? 345 TRP C NE1 1 
ATOM   10127 C CE2 . TRP C 1 345 ? 126.294 118.610 181.347 1.00 64.41  ? 345 TRP C CE2 1 
ATOM   10128 C CE3 . TRP C 1 345 ? 124.186 118.855 180.193 1.00 64.41  ? 345 TRP C CE3 1 
ATOM   10129 C CZ2 . TRP C 1 345 ? 125.947 119.577 182.284 1.00 64.41  ? 345 TRP C CZ2 1 
ATOM   10130 C CZ3 . TRP C 1 345 ? 123.844 119.815 181.124 1.00 64.41  ? 345 TRP C CZ3 1 
ATOM   10131 C CH2 . TRP C 1 345 ? 124.720 120.167 182.156 1.00 64.41  ? 345 TRP C CH2 1 
ATOM   10132 N N   . GLU C 1 346 ? 126.273 113.427 176.717 1.00 65.81  ? 346 GLU C N   1 
ATOM   10133 C CA  . GLU C 1 346 ? 125.714 112.458 175.782 1.00 65.81  ? 346 GLU C CA  1 
ATOM   10134 C C   . GLU C 1 346 ? 124.248 112.158 176.071 1.00 65.81  ? 346 GLU C C   1 
ATOM   10135 O O   . GLU C 1 346 ? 123.478 111.899 175.140 1.00 65.81  ? 346 GLU C O   1 
ATOM   10136 C CB  . GLU C 1 346 ? 126.532 111.166 175.819 1.00 65.81  ? 346 GLU C CB  1 
ATOM   10137 C CG  . GLU C 1 346 ? 126.058 110.099 174.845 1.00 65.81  ? 346 GLU C CG  1 
ATOM   10138 C CD  . GLU C 1 346 ? 126.223 110.515 173.397 1.00 65.81  ? 346 GLU C CD  1 
ATOM   10139 O OE1 . GLU C 1 346 ? 127.105 111.351 173.111 1.00 65.81  ? 346 GLU C OE1 1 
ATOM   10140 O OE2 . GLU C 1 346 ? 125.463 110.010 172.545 1.00 65.81  ? 346 GLU C OE2 1 
ATOM   10141 N N   . GLY C 1 347 ? 123.843 112.200 177.337 1.00 70.46  ? 347 GLY C N   1 
ATOM   10142 C CA  . GLY C 1 347 ? 122.498 111.844 177.732 1.00 70.46  ? 347 GLY C CA  1 
ATOM   10143 C C   . GLY C 1 347 ? 121.455 112.926 177.583 1.00 70.46  ? 347 GLY C C   1 
ATOM   10144 O O   . GLY C 1 347 ? 120.339 112.765 178.082 1.00 70.46  ? 347 GLY C O   1 
ATOM   10145 N N   . MET C 1 348 ? 121.778 114.027 176.912 1.00 68.93  ? 348 MET C N   1 
ATOM   10146 C CA  . MET C 1 348 ? 120.843 115.126 176.711 1.00 68.93  ? 348 MET C CA  1 
ATOM   10147 C C   . MET C 1 348 ? 120.324 115.089 175.279 1.00 68.93  ? 348 MET C C   1 
ATOM   10148 O O   . MET C 1 348 ? 121.113 115.111 174.327 1.00 68.93  ? 348 MET C O   1 
ATOM   10149 C CB  . MET C 1 348 ? 121.508 116.469 177.007 1.00 68.93  ? 348 MET C CB  1 
ATOM   10150 C CG  . MET C 1 348 ? 120.589 117.650 176.796 1.00 68.93  ? 348 MET C CG  1 
ATOM   10151 S SD  . MET C 1 348 ? 121.449 119.227 176.802 1.00 68.93  ? 348 MET C SD  1 
ATOM   10152 C CE  . MET C 1 348 ? 120.251 120.221 177.680 1.00 68.93  ? 348 MET C CE  1 
ATOM   10153 N N   . ILE C 1 349 ? 119.001 115.035 175.129 1.00 72.93  ? 349 ILE C N   1 
ATOM   10154 C CA  . ILE C 1 349 ? 118.375 114.923 173.817 1.00 72.93  ? 349 ILE C CA  1 
ATOM   10155 C C   . ILE C 1 349 ? 117.261 115.952 173.672 1.00 72.93  ? 349 ILE C C   1 
ATOM   10156 O O   . ILE C 1 349 ? 116.580 116.001 172.642 1.00 72.93  ? 349 ILE C O   1 
ATOM   10157 C CB  . ILE C 1 349 ? 117.830 113.502 173.584 1.00 72.93  ? 349 ILE C CB  1 
ATOM   10158 C CG1 . ILE C 1 349 ? 116.831 113.132 174.684 1.00 72.93  ? 349 ILE C CG1 1 
ATOM   10159 C CG2 . ILE C 1 349 ? 118.966 112.492 173.524 1.00 72.93  ? 349 ILE C CG2 1 
ATOM   10160 C CD1 . ILE C 1 349 ? 116.134 111.809 174.460 1.00 72.93  ? 349 ILE C CD1 1 
ATOM   10161 N N   . ASP C 1 350 ? 117.065 116.780 174.696 1.00 72.45  ? 350 ASP C N   1 
ATOM   10162 C CA  . ASP C 1 350 ? 115.961 117.730 174.718 1.00 72.45  ? 350 ASP C CA  1 
ATOM   10163 C C   . ASP C 1 350 ? 116.370 119.143 174.323 1.00 72.45  ? 350 ASP C C   1 
ATOM   10164 O O   . ASP C 1 350 ? 115.507 120.023 174.252 1.00 72.45  ? 350 ASP C O   1 
ATOM   10165 C CB  . ASP C 1 350 ? 115.315 117.754 176.107 1.00 72.45  ? 350 ASP C CB  1 
ATOM   10166 C CG  . ASP C 1 350 ? 113.866 118.196 176.067 1.00 72.45  ? 350 ASP C CG  1 
ATOM   10167 O OD1 . ASP C 1 350 ? 113.181 117.898 175.067 1.00 72.45  ? 350 ASP C OD1 1 
ATOM   10168 O OD2 . ASP C 1 350 ? 113.414 118.846 177.033 1.00 72.45  ? 350 ASP C OD2 1 
ATOM   10169 N N   . GLY C 1 351 ? 117.648 119.384 174.061 1.00 67.15  ? 351 GLY C N   1 
ATOM   10170 C CA  . GLY C 1 351 ? 118.079 120.720 173.693 1.00 67.15  ? 351 GLY C CA  1 
ATOM   10171 C C   . GLY C 1 351 ? 119.570 120.751 173.450 1.00 67.15  ? 351 GLY C C   1 
ATOM   10172 O O   . GLY C 1 351 ? 120.260 119.728 173.516 1.00 67.15  ? 351 GLY C O   1 
ATOM   10173 N N   . TRP C 1 352 ? 120.060 121.956 173.162 1.00 59.48  ? 352 TRP C N   1 
ATOM   10174 C CA  . TRP C 1 352 ? 121.480 122.171 172.911 1.00 59.48  ? 352 TRP C CA  1 
ATOM   10175 C C   . TRP C 1 352 ? 122.234 122.562 174.176 1.00 59.48  ? 352 TRP C C   1 
ATOM   10176 O O   . TRP C 1 352 ? 123.374 122.130 174.373 1.00 59.48  ? 352 TRP C O   1 
ATOM   10177 C CB  . TRP C 1 352 ? 121.665 123.245 171.835 1.00 59.48  ? 352 TRP C CB  1 
ATOM   10178 C CG  . TRP C 1 352 ? 121.333 122.775 170.448 1.00 59.48  ? 352 TRP C CG  1 
ATOM   10179 C CD1 . TRP C 1 352 ? 120.539 121.720 170.108 1.00 59.48  ? 352 TRP C CD1 1 
ATOM   10180 C CD2 . TRP C 1 352 ? 121.787 123.347 169.216 1.00 59.48  ? 352 TRP C CD2 1 
ATOM   10181 N NE1 . TRP C 1 352 ? 120.470 121.598 168.742 1.00 59.48  ? 352 TRP C NE1 1 
ATOM   10182 C CE2 . TRP C 1 352 ? 121.228 122.586 168.171 1.00 59.48  ? 352 TRP C CE2 1 
ATOM   10183 C CE3 . TRP C 1 352 ? 122.612 124.429 168.895 1.00 59.48  ? 352 TRP C CE3 1 
ATOM   10184 C CZ2 . TRP C 1 352 ? 121.468 122.871 166.829 1.00 59.48  ? 352 TRP C CZ2 1 
ATOM   10185 C CZ3 . TRP C 1 352 ? 122.849 124.710 167.563 1.00 59.48  ? 352 TRP C CZ3 1 
ATOM   10186 C CH2 . TRP C 1 352 ? 122.278 123.935 166.547 1.00 59.48  ? 352 TRP C CH2 1 
ATOM   10187 N N   . TYR C 1 353 ? 121.617 123.369 175.036 1.00 59.06  ? 353 TYR C N   1 
ATOM   10188 C CA  . TYR C 1 353 ? 122.206 123.778 176.301 1.00 59.06  ? 353 TYR C CA  1 
ATOM   10189 C C   . TYR C 1 353 ? 121.208 123.523 177.421 1.00 59.06  ? 353 TYR C C   1 
ATOM   10190 O O   . TYR C 1 353 ? 119.994 123.515 177.206 1.00 59.06  ? 353 TYR C O   1 
ATOM   10191 C CB  . TYR C 1 353 ? 122.609 125.259 176.290 1.00 59.06  ? 353 TYR C CB  1 
ATOM   10192 C CG  . TYR C 1 353 ? 123.248 125.716 175.001 1.00 59.06  ? 353 TYR C CG  1 
ATOM   10193 C CD1 . TYR C 1 353 ? 124.598 125.502 174.758 1.00 59.06  ? 353 TYR C CD1 1 
ATOM   10194 C CD2 . TYR C 1 353 ? 122.501 126.360 174.026 1.00 59.06  ? 353 TYR C CD2 1 
ATOM   10195 C CE1 . TYR C 1 353 ? 125.184 125.918 173.581 1.00 59.06  ? 353 TYR C CE1 1 
ATOM   10196 C CE2 . TYR C 1 353 ? 123.078 126.779 172.847 1.00 59.06  ? 353 TYR C CE2 1 
ATOM   10197 C CZ  . TYR C 1 353 ? 124.418 126.556 172.630 1.00 59.06  ? 353 TYR C CZ  1 
ATOM   10198 O OH  . TYR C 1 353 ? 124.991 126.975 171.455 1.00 59.06  ? 353 TYR C OH  1 
ATOM   10199 N N   . GLY C 1 354 ? 121.730 123.312 178.623 1.00 65.15  ? 354 GLY C N   1 
ATOM   10200 C CA  . GLY C 1 354 ? 120.866 123.042 179.757 1.00 65.15  ? 354 GLY C CA  1 
ATOM   10201 C C   . GLY C 1 354 ? 121.653 123.011 181.047 1.00 65.15  ? 354 GLY C C   1 
ATOM   10202 O O   . GLY C 1 354 ? 122.856 123.291 181.080 1.00 65.15  ? 354 GLY C O   1 
ATOM   10203 N N   . PHE C 1 355 ? 120.946 122.659 182.117 1.00 69.60  ? 355 PHE C N   1 
ATOM   10204 C CA  . PHE C 1 355 ? 121.493 122.652 183.464 1.00 69.60  ? 355 PHE C CA  1 
ATOM   10205 C C   . PHE C 1 355 ? 121.461 121.245 184.044 1.00 69.60  ? 355 PHE C C   1 
ATOM   10206 O O   . PHE C 1 355 ? 120.576 120.444 183.731 1.00 69.60  ? 355 PHE C O   1 
ATOM   10207 C CB  . PHE C 1 355 ? 120.710 123.594 184.391 1.00 69.60  ? 355 PHE C CB  1 
ATOM   10208 C CG  . PHE C 1 355 ? 120.644 125.015 183.909 1.00 69.60  ? 355 PHE C CG  1 
ATOM   10209 C CD1 . PHE C 1 355 ? 119.670 125.410 183.007 1.00 69.60  ? 355 PHE C CD1 1 
ATOM   10210 C CD2 . PHE C 1 355 ? 121.544 125.959 184.371 1.00 69.60  ? 355 PHE C CD2 1 
ATOM   10211 C CE1 . PHE C 1 355 ? 119.603 126.716 182.568 1.00 69.60  ? 355 PHE C CE1 1 
ATOM   10212 C CE2 . PHE C 1 355 ? 121.482 127.267 183.935 1.00 69.60  ? 355 PHE C CE2 1 
ATOM   10213 C CZ  . PHE C 1 355 ? 120.510 127.646 183.032 1.00 69.60  ? 355 PHE C CZ  1 
ATOM   10214 N N   . ARG C 1 356 ? 122.441 120.953 184.895 1.00 71.07  ? 356 ARG C N   1 
ATOM   10215 C CA  . ARG C 1 356 ? 122.442 119.760 185.729 1.00 71.07  ? 356 ARG C CA  1 
ATOM   10216 C C   . ARG C 1 356 ? 122.721 120.186 187.160 1.00 71.07  ? 356 ARG C C   1 
ATOM   10217 O O   . ARG C 1 356 ? 123.679 120.924 187.413 1.00 71.07  ? 356 ARG C O   1 
ATOM   10218 C CB  . ARG C 1 356 ? 123.486 118.739 185.265 1.00 71.07  ? 356 ARG C CB  1 
ATOM   10219 C CG  . ARG C 1 356 ? 122.968 117.742 184.248 1.00 71.07  ? 356 ARG C CG  1 
ATOM   10220 C CD  . ARG C 1 356 ? 123.997 116.664 183.956 1.00 71.07  ? 356 ARG C CD  1 
ATOM   10221 N NE  . ARG C 1 356 ? 123.642 115.877 182.782 1.00 71.07  ? 356 ARG C NE  1 
ATOM   10222 C CZ  . ARG C 1 356 ? 124.429 114.969 182.223 1.00 71.07  ? 356 ARG C CZ  1 
ATOM   10223 N NH1 . ARG C 1 356 ? 125.626 114.696 182.716 1.00 71.07  ? 356 ARG C NH1 1 
ATOM   10224 N NH2 . ARG C 1 356 ? 124.006 114.319 181.144 1.00 71.07  ? 356 ARG C NH2 1 
ATOM   10225 N N   . HIS C 1 357 ? 121.892 119.726 188.092 1.00 81.78  ? 357 HIS C N   1 
ATOM   10226 C CA  . HIS C 1 357 ? 121.983 120.152 189.479 1.00 81.78  ? 357 HIS C CA  1 
ATOM   10227 C C   . HIS C 1 357 ? 122.125 118.947 190.395 1.00 81.78  ? 357 HIS C C   1 
ATOM   10228 O O   . HIS C 1 357 ? 121.505 117.904 190.169 1.00 81.78  ? 357 HIS C O   1 
ATOM   10229 C CB  . HIS C 1 357 ? 120.755 120.981 189.888 1.00 81.78  ? 357 HIS C CB  1 
ATOM   10230 C CG  . HIS C 1 357 ? 119.470 120.212 189.874 1.00 81.78  ? 357 HIS C CG  1 
ATOM   10231 N ND1 . HIS C 1 357 ? 119.141 119.290 190.845 1.00 81.78  ? 357 HIS C ND1 1 
ATOM   10232 C CD2 . HIS C 1 357 ? 118.430 120.230 189.008 1.00 81.78  ? 357 HIS C CD2 1 
ATOM   10233 C CE1 . HIS C 1 357 ? 117.956 118.774 190.576 1.00 81.78  ? 357 HIS C CE1 1 
ATOM   10234 N NE2 . HIS C 1 357 ? 117.502 119.327 189.467 1.00 81.78  ? 357 HIS C NE2 1 
ATOM   10235 N N   . GLN C 1 358 ? 122.948 119.100 191.428 1.00 85.55  ? 358 GLN C N   1 
ATOM   10236 C CA  . GLN C 1 358 ? 123.076 118.121 192.497 1.00 85.55  ? 358 GLN C CA  1 
ATOM   10237 C C   . GLN C 1 358 ? 122.484 118.722 193.762 1.00 85.55  ? 358 GLN C C   1 
ATOM   10238 O O   . GLN C 1 358 ? 122.849 119.834 194.155 1.00 85.55  ? 358 GLN C O   1 
ATOM   10239 C CB  . GLN C 1 358 ? 124.537 117.725 192.722 1.00 85.55  ? 358 GLN C CB  1 
ATOM   10240 C CG  . GLN C 1 358 ? 124.714 116.360 193.365 1.00 85.55  ? 358 GLN C CG  1 
ATOM   10241 C CD  . GLN C 1 358 ? 126.131 115.838 193.243 1.00 85.55  ? 358 GLN C CD  1 
ATOM   10242 O OE1 . GLN C 1 358 ? 126.625 115.601 192.141 1.00 85.55  ? 358 GLN C OE1 1 
ATOM   10243 N NE2 . GLN C 1 358 ? 126.795 115.657 194.379 1.00 85.55  ? 358 GLN C NE2 1 
ATOM   10244 N N   . ASN C 1 359 ? 121.572 117.989 194.394 1.00 93.18  ? 359 ASN C N   1 
ATOM   10245 C CA  . ASN C 1 359 ? 120.798 118.516 195.505 1.00 93.18  ? 359 ASN C CA  1 
ATOM   10246 C C   . ASN C 1 359 ? 120.646 117.443 196.571 1.00 93.18  ? 359 ASN C C   1 
ATOM   10247 O O   . ASN C 1 359 ? 120.993 116.277 196.368 1.00 93.18  ? 359 ASN C O   1 
ATOM   10248 C CB  . ASN C 1 359 ? 119.425 119.007 195.033 1.00 93.18  ? 359 ASN C CB  1 
ATOM   10249 C CG  . ASN C 1 359 ? 118.886 120.135 195.882 1.00 93.18  ? 359 ASN C CG  1 
ATOM   10250 O OD1 . ASN C 1 359 ? 119.563 120.628 196.783 1.00 93.18  ? 359 ASN C OD1 1 
ATOM   10251 N ND2 . ASN C 1 359 ? 117.661 120.553 195.596 1.00 93.18  ? 359 ASN C ND2 1 
ATOM   10252 N N   . SER C 1 360 ? 120.125 117.859 197.728 1.00 96.14  ? 360 SER C N   1 
ATOM   10253 C CA  . SER C 1 360 ? 119.830 116.903 198.790 1.00 96.14  ? 360 SER C CA  1 
ATOM   10254 C C   . SER C 1 360 ? 118.764 115.908 198.349 1.00 96.14  ? 360 SER C C   1 
ATOM   10255 O O   . SER C 1 360 ? 118.858 114.712 198.648 1.00 96.14  ? 360 SER C O   1 
ATOM   10256 C CB  . SER C 1 360 ? 119.387 117.642 200.053 1.00 96.14  ? 360 SER C CB  1 
ATOM   10257 O OG  . SER C 1 360 ? 118.206 118.388 199.819 1.00 96.14  ? 360 SER C OG  1 
ATOM   10258 N N   . GLU C 1 361 ? 117.738 116.388 197.643 1.00 95.40  ? 361 GLU C N   1 
ATOM   10259 C CA  . GLU C 1 361 ? 116.703 115.493 197.136 1.00 95.40  ? 361 GLU C CA  1 
ATOM   10260 C C   . GLU C 1 361 ? 117.268 114.522 196.107 1.00 95.40  ? 361 GLU C C   1 
ATOM   10261 O O   . GLU C 1 361 ? 116.954 113.326 196.133 1.00 95.40  ? 361 GLU C O   1 
ATOM   10262 C CB  . GLU C 1 361 ? 115.559 116.307 196.534 1.00 95.40  ? 361 GLU C CB  1 
ATOM   10263 C CG  . GLU C 1 361 ? 114.992 117.362 197.469 1.00 95.40  ? 361 GLU C CG  1 
ATOM   10264 C CD  . GLU C 1 361 ? 113.845 118.133 196.849 1.00 95.40  ? 361 GLU C CD  1 
ATOM   10265 O OE1 . GLU C 1 361 ? 113.495 117.843 195.686 1.00 95.40  ? 361 GLU C OE1 1 
ATOM   10266 O OE2 . GLU C 1 361 ? 113.297 119.030 197.522 1.00 95.40  ? 361 GLU C OE2 1 
ATOM   10267 N N   . GLY C 1 362 ? 118.098 115.010 195.203 1.00 91.91  ? 362 GLY C N   1 
ATOM   10268 C CA  . GLY C 1 362 ? 118.687 114.167 194.182 1.00 91.91  ? 362 GLY C CA  1 
ATOM   10269 C C   . GLY C 1 362 ? 119.099 114.991 192.980 1.00 91.91  ? 362 GLY C C   1 
ATOM   10270 O O   . GLY C 1 362 ? 118.980 116.213 192.959 1.00 91.91  ? 362 GLY C O   1 
ATOM   10271 N N   . THR C 1 363 ? 119.590 114.282 191.968 1.00 85.43  ? 363 THR C N   1 
ATOM   10272 C CA  . THR C 1 363 ? 120.064 114.916 190.749 1.00 85.43  ? 363 THR C CA  1 
ATOM   10273 C C   . THR C 1 363 ? 118.899 115.244 189.818 1.00 85.43  ? 363 THR C C   1 
ATOM   10274 O O   . THR C 1 363 ? 117.761 114.811 190.021 1.00 85.43  ? 363 THR C O   1 
ATOM   10275 C CB  . THR C 1 363 ? 121.068 114.016 190.029 1.00 85.43  ? 363 THR C CB  1 
ATOM   10276 O OG1 . THR C 1 363 ? 120.394 112.863 189.509 1.00 85.43  ? 363 THR C OG1 1 
ATOM   10277 C CG2 . THR C 1 363 ? 122.159 113.566 190.987 1.00 85.43  ? 363 THR C CG2 1 
ATOM   10278 N N   . GLY C 1 364 ? 119.201 116.025 188.785 1.00 80.72  ? 364 GLY C N   1 
ATOM   10279 C CA  . GLY C 1 364 ? 118.200 116.416 187.812 1.00 80.72  ? 364 GLY C CA  1 
ATOM   10280 C C   . GLY C 1 364 ? 118.860 116.949 186.559 1.00 80.72  ? 364 GLY C C   1 
ATOM   10281 O O   . GLY C 1 364 ? 120.086 116.978 186.438 1.00 80.72  ? 364 GLY C O   1 
ATOM   10282 N N   . GLN C 1 365 ? 118.019 117.371 185.618 1.00 73.29  ? 365 GLN C N   1 
ATOM   10283 C CA  . GLN C 1 365 ? 118.496 117.908 184.351 1.00 73.29  ? 365 GLN C CA  1 
ATOM   10284 C C   . GLN C 1 365 ? 117.377 118.706 183.701 1.00 73.29  ? 365 GLN C C   1 
ATOM   10285 O O   . GLN C 1 365 ? 116.194 118.446 183.935 1.00 73.29  ? 365 GLN C O   1 
ATOM   10286 C CB  . GLN C 1 365 ? 118.972 116.793 183.413 1.00 73.29  ? 365 GLN C CB  1 
ATOM   10287 C CG  . GLN C 1 365 ? 119.921 117.257 182.322 1.00 73.29  ? 365 GLN C CG  1 
ATOM   10288 C CD  . GLN C 1 365 ? 119.869 116.377 181.091 1.00 73.29  ? 365 GLN C CD  1 
ATOM   10289 O OE1 . GLN C 1 365 ? 120.683 115.469 180.928 1.00 73.29  ? 365 GLN C OE1 1 
ATOM   10290 N NE2 . GLN C 1 365 ? 118.907 116.642 180.215 1.00 73.29  ? 365 GLN C NE2 1 
ATOM   10291 N N   . ALA C 1 366 ? 117.765 119.680 182.883 1.00 70.92  ? 366 ALA C N   1 
ATOM   10292 C CA  . ALA C 1 366 ? 116.814 120.514 182.162 1.00 70.92  ? 366 ALA C CA  1 
ATOM   10293 C C   . ALA C 1 366 ? 117.495 121.031 180.901 1.00 70.92  ? 366 ALA C C   1 
ATOM   10294 O O   . ALA C 1 366 ? 118.629 120.660 180.587 1.00 70.92  ? 366 ALA C O   1 
ATOM   10295 C CB  . ALA C 1 366 ? 116.302 121.660 183.039 1.00 70.92  ? 366 ALA C CB  1 
ATOM   10296 N N   . ALA C 1 367 ? 116.788 121.893 180.175 1.00 68.18  ? 367 ALA C N   1 
ATOM   10297 C CA  . ALA C 1 367 ? 117.299 122.485 178.949 1.00 68.18  ? 367 ALA C CA  1 
ATOM   10298 C C   . ALA C 1 367 ? 116.915 123.956 178.892 1.00 68.18  ? 367 ALA C C   1 
ATOM   10299 O O   . ALA C 1 367 ? 115.918 124.377 179.483 1.00 68.18  ? 367 ALA C O   1 
ATOM   10300 C CB  . ALA C 1 367 ? 116.766 121.757 177.708 1.00 68.18  ? 367 ALA C CB  1 
ATOM   10301 N N   . ASP C 1 368 ? 117.720 124.734 178.174 1.00 65.96  ? 368 ASP C N   1 
ATOM   10302 C CA  . ASP C 1 368 ? 117.480 126.160 177.996 1.00 65.96  ? 368 ASP C CA  1 
ATOM   10303 C C   . ASP C 1 368 ? 116.947 126.399 176.589 1.00 65.96  ? 368 ASP C C   1 
ATOM   10304 O O   . ASP C 1 368 ? 117.644 126.137 175.603 1.00 65.96  ? 368 ASP C O   1 
ATOM   10305 C CB  . ASP C 1 368 ? 118.758 126.962 178.236 1.00 65.96  ? 368 ASP C CB  1 
ATOM   10306 C CG  . ASP C 1 368 ? 118.482 128.423 178.535 1.00 65.96  ? 368 ASP C CG  1 
ATOM   10307 O OD1 . ASP C 1 368 ? 117.768 129.073 177.744 1.00 65.96  ? 368 ASP C OD1 1 
ATOM   10308 O OD2 . ASP C 1 368 ? 118.978 128.922 179.566 1.00 65.96  ? 368 ASP C OD2 1 
ATOM   10309 N N   . LEU C 1 369 ? 115.710 126.892 176.501 1.00 66.12  ? 369 LEU C N   1 
ATOM   10310 C CA  . LEU C 1 369 ? 115.088 127.116 175.202 1.00 66.12  ? 369 LEU C CA  1 
ATOM   10311 C C   . LEU C 1 369 ? 115.603 128.374 174.516 1.00 66.12  ? 369 LEU C C   1 
ATOM   10312 O O   . LEU C 1 369 ? 115.714 128.397 173.286 1.00 66.12  ? 369 LEU C O   1 
ATOM   10313 C CB  . LEU C 1 369 ? 113.568 127.195 175.351 1.00 66.12  ? 369 LEU C CB  1 
ATOM   10314 C CG  . LEU C 1 369 ? 112.880 126.046 176.090 1.00 66.12  ? 369 LEU C CG  1 
ATOM   10315 C CD1 . LEU C 1 369 ? 111.370 126.179 175.984 1.00 66.12  ? 369 LEU C CD1 1 
ATOM   10316 C CD2 . LEU C 1 369 ? 113.344 124.698 175.552 1.00 66.12  ? 369 LEU C CD2 1 
ATOM   10317 N N   . LYS C 1 370 ? 115.914 129.424 175.279 1.00 64.95  ? 370 LYS C N   1 
ATOM   10318 C CA  . LYS C 1 370 ? 116.272 130.702 174.670 1.00 64.95  ? 370 LYS C CA  1 
ATOM   10319 C C   . LYS C 1 370 ? 117.590 130.610 173.908 1.00 64.95  ? 370 LYS C C   1 
ATOM   10320 O O   . LYS C 1 370 ? 117.672 131.019 172.744 1.00 64.95  ? 370 LYS C O   1 
ATOM   10321 C CB  . LYS C 1 370 ? 116.342 131.790 175.742 1.00 64.95  ? 370 LYS C CB  1 
ATOM   10322 C CG  . LYS C 1 370 ? 114.994 132.162 176.336 1.00 64.95  ? 370 LYS C CG  1 
ATOM   10323 C CD  . LYS C 1 370 ? 115.128 133.293 177.342 1.00 64.95  ? 370 LYS C CD  1 
ATOM   10324 C CE  . LYS C 1 370 ? 113.766 133.764 177.828 1.00 64.95  ? 370 LYS C CE  1 
ATOM   10325 N NZ  . LYS C 1 370 ? 113.880 134.890 178.796 1.00 64.95  ? 370 LYS C NZ  1 
ATOM   10326 N N   . SER C 1 371 ? 118.634 130.079 174.549 1.00 62.88  ? 371 SER C N   1 
ATOM   10327 C CA  . SER C 1 371 ? 119.933 129.976 173.890 1.00 62.88  ? 371 SER C CA  1 
ATOM   10328 C C   . SER C 1 371 ? 119.883 129.015 172.709 1.00 62.88  ? 371 SER C C   1 
ATOM   10329 O O   . SER C 1 371 ? 120.461 129.292 171.648 1.00 62.88  ? 371 SER C O   1 
ATOM   10330 C CB  . SER C 1 371 ? 120.996 129.539 174.897 1.00 62.88  ? 371 SER C CB  1 
ATOM   10331 O OG  . SER C 1 371 ? 120.578 128.392 175.615 1.00 62.88  ? 371 SER C OG  1 
ATOM   10332 N N   . THR C 1 372 ? 119.199 127.880 172.875 1.00 61.04  ? 372 THR C N   1 
ATOM   10333 C CA  . THR C 1 372 ? 119.061 126.926 171.779 1.00 61.04  ? 372 THR C CA  1 
ATOM   10334 C C   . THR C 1 372 ? 118.349 127.557 170.591 1.00 61.04  ? 372 THR C C   1 
ATOM   10335 O O   . THR C 1 372 ? 118.779 127.398 169.442 1.00 61.04  ? 372 THR C O   1 
ATOM   10336 C CB  . THR C 1 372 ? 118.304 125.686 172.256 1.00 61.04  ? 372 THR C CB  1 
ATOM   10337 O OG1 . THR C 1 372 ? 119.036 125.051 173.311 1.00 61.04  ? 372 THR C OG1 1 
ATOM   10338 C CG2 . THR C 1 372 ? 118.117 124.702 171.114 1.00 61.04  ? 372 THR C CG2 1 
ATOM   10339 N N   . GLN C 1 373 ? 117.265 128.291 170.851 1.00 61.00  ? 373 GLN C N   1 
ATOM   10340 C CA  . GLN C 1 373 ? 116.524 128.921 169.766 1.00 61.00  ? 373 GLN C CA  1 
ATOM   10341 C C   . GLN C 1 373 ? 117.341 130.020 169.103 1.00 61.00  ? 373 GLN C C   1 
ATOM   10342 O O   . GLN C 1 373 ? 117.277 130.191 167.882 1.00 61.00  ? 373 GLN C O   1 
ATOM   10343 C CB  . GLN C 1 373 ? 115.197 129.473 170.283 1.00 61.00  ? 373 GLN C CB  1 
ATOM   10344 C CG  . GLN C 1 373 ? 114.190 129.762 169.185 1.00 61.00  ? 373 GLN C CG  1 
ATOM   10345 C CD  . GLN C 1 373 ? 113.848 128.529 168.371 1.00 61.00  ? 373 GLN C CD  1 
ATOM   10346 O OE1 . GLN C 1 373 ? 113.795 127.417 168.898 1.00 61.00  ? 373 GLN C OE1 1 
ATOM   10347 N NE2 . GLN C 1 373 ? 113.619 128.719 167.077 1.00 61.00  ? 373 GLN C NE2 1 
ATOM   10348 N N   . ALA C 1 374 ? 118.112 130.778 169.885 1.00 59.02  ? 374 ALA C N   1 
ATOM   10349 C CA  . ALA C 1 374 ? 118.965 131.808 169.301 1.00 59.02  ? 374 ALA C CA  1 
ATOM   10350 C C   . ALA C 1 374 ? 120.005 131.192 168.374 1.00 59.02  ? 374 ALA C C   1 
ATOM   10351 O O   . ALA C 1 374 ? 120.220 131.670 167.252 1.00 59.02  ? 374 ALA C O   1 
ATOM   10352 C CB  . ALA C 1 374 ? 119.636 132.622 170.406 1.00 59.02  ? 374 ALA C CB  1 
ATOM   10353 N N   . ALA C 1 375 ? 120.653 130.113 168.825 1.00 57.85  ? 375 ALA C N   1 
ATOM   10354 C CA  . ALA C 1 375 ? 121.638 129.439 167.986 1.00 57.85  ? 375 ALA C CA  1 
ATOM   10355 C C   . ALA C 1 375 ? 120.997 128.873 166.725 1.00 57.85  ? 375 ALA C C   1 
ATOM   10356 O O   . ALA C 1 375 ? 121.558 128.987 165.629 1.00 57.85  ? 375 ALA C O   1 
ATOM   10357 C CB  . ALA C 1 375 ? 122.334 128.334 168.778 1.00 57.85  ? 375 ALA C CB  1 
ATOM   10358 N N   . ILE C 1 376 ? 119.816 128.264 166.861 1.00 56.86  ? 376 ILE C N   1 
ATOM   10359 C CA  . ILE C 1 376 ? 119.135 127.685 165.705 1.00 56.86  ? 376 ILE C CA  1 
ATOM   10360 C C   . ILE C 1 376 ? 118.757 128.772 164.705 1.00 56.86  ? 376 ILE C C   1 
ATOM   10361 O O   . ILE C 1 376 ? 118.943 128.611 163.492 1.00 56.86  ? 376 ILE C O   1 
ATOM   10362 C CB  . ILE C 1 376 ? 117.907 126.878 166.166 1.00 56.86  ? 376 ILE C CB  1 
ATOM   10363 C CG1 . ILE C 1 376 ? 118.325 125.465 166.574 1.00 56.86  ? 376 ILE C CG1 1 
ATOM   10364 C CG2 . ILE C 1 376 ? 116.850 126.825 165.075 1.00 56.86  ? 376 ILE C CG2 1 
ATOM   10365 C CD1 . ILE C 1 376 ? 117.294 124.742 167.406 1.00 56.86  ? 376 ILE C CD1 1 
ATOM   10366 N N   . ASP C 1 377 ? 118.227 129.895 165.195 1.00 57.10  ? 377 ASP C N   1 
ATOM   10367 C CA  . ASP C 1 377 ? 117.827 130.981 164.307 1.00 57.10  ? 377 ASP C CA  1 
ATOM   10368 C C   . ASP C 1 377 ? 119.029 131.587 163.595 1.00 57.10  ? 377 ASP C C   1 
ATOM   10369 O O   . ASP C 1 377 ? 118.949 131.924 162.409 1.00 57.10  ? 377 ASP C O   1 
ATOM   10370 C CB  . ASP C 1 377 ? 117.073 132.052 165.094 1.00 57.10  ? 377 ASP C CB  1 
ATOM   10371 C CG  . ASP C 1 377 ? 115.736 131.559 165.613 1.00 57.10  ? 377 ASP C CG  1 
ATOM   10372 O OD1 . ASP C 1 377 ? 115.281 130.487 165.162 1.00 57.10  ? 377 ASP C OD1 1 
ATOM   10373 O OD2 . ASP C 1 377 ? 115.141 132.243 166.472 1.00 57.10  ? 377 ASP C OD2 1 
ATOM   10374 N N   . GLN C 1 378 ? 120.150 131.744 164.304 1.00 52.36  ? 378 GLN C N   1 
ATOM   10375 C CA  . GLN C 1 378 ? 121.357 132.242 163.653 1.00 52.36  ? 378 GLN C CA  1 
ATOM   10376 C C   . GLN C 1 378 ? 121.854 131.267 162.593 1.00 52.36  ? 378 GLN C C   1 
ATOM   10377 O O   . GLN C 1 378 ? 122.282 131.680 161.509 1.00 52.36  ? 378 GLN C O   1 
ATOM   10378 C CB  . GLN C 1 378 ? 122.446 132.505 164.693 1.00 52.36  ? 378 GLN C CB  1 
ATOM   10379 C CG  . GLN C 1 378 ? 122.158 133.675 165.616 1.00 52.36  ? 378 GLN C CG  1 
ATOM   10380 C CD  . GLN C 1 378 ? 123.402 134.189 166.309 1.00 52.36  ? 378 GLN C CD  1 
ATOM   10381 O OE1 . GLN C 1 378 ? 124.520 133.957 165.852 1.00 52.36  ? 378 GLN C OE1 1 
ATOM   10382 N NE2 . GLN C 1 378 ? 123.215 134.890 167.419 1.00 52.36  ? 378 GLN C NE2 1 
ATOM   10383 N N   . ILE C 1 379 ? 121.806 129.967 162.890 1.00 51.59  ? 379 ILE C N   1 
ATOM   10384 C CA  . ILE C 1 379 ? 122.315 128.966 161.956 1.00 51.59  ? 379 ILE C CA  1 
ATOM   10385 C C   . ILE C 1 379 ? 121.399 128.835 160.742 1.00 51.59  ? 379 ILE C C   1 
ATOM   10386 O O   . ILE C 1 379 ? 121.869 128.695 159.607 1.00 51.59  ? 379 ILE C O   1 
ATOM   10387 C CB  . ILE C 1 379 ? 122.506 127.624 162.686 1.00 51.59  ? 379 ILE C CB  1 
ATOM   10388 C CG1 . ILE C 1 379 ? 123.792 127.659 163.512 1.00 51.59  ? 379 ILE C CG1 1 
ATOM   10389 C CG2 . ILE C 1 379 ? 122.538 126.466 161.703 1.00 51.59  ? 379 ILE C CG2 1 
ATOM   10390 C CD1 . ILE C 1 379 ? 123.919 126.528 164.503 1.00 51.59  ? 379 ILE C CD1 1 
ATOM   10391 N N   . ASN C 1 380 ? 120.085 128.882 160.955 1.00 53.37  ? 380 ASN C N   1 
ATOM   10392 C CA  . ASN C 1 380 ? 119.135 128.661 159.870 1.00 53.37  ? 380 ASN C CA  1 
ATOM   10393 C C   . ASN C 1 380 ? 119.206 129.786 158.842 1.00 53.37  ? 380 ASN C C   1 
ATOM   10394 O O   . ASN C 1 380 ? 119.227 130.968 159.197 1.00 53.37  ? 380 ASN C O   1 
ATOM   10395 C CB  . ASN C 1 380 ? 117.717 128.547 160.426 1.00 53.37  ? 380 ASN C CB  1 
ATOM   10396 C CG  . ASN C 1 380 ? 117.280 127.109 160.616 1.00 53.37  ? 380 ASN C CG  1 
ATOM   10397 O OD1 . ASN C 1 380 ? 117.979 126.178 160.218 1.00 53.37  ? 380 ASN C OD1 1 
ATOM   10398 N ND2 . ASN C 1 380 ? 116.119 126.920 161.232 1.00 53.37  ? 380 ASN C ND2 1 
ATOM   10399 N N   . GLY C 1 381 ? 119.233 129.412 157.565 1.00 51.69  ? 381 GLY C N   1 
ATOM   10400 C CA  . GLY C 1 381 ? 119.293 130.390 156.494 1.00 51.69  ? 381 GLY C CA  1 
ATOM   10401 C C   . GLY C 1 381 ? 120.619 131.105 156.376 1.00 51.69  ? 381 GLY C C   1 
ATOM   10402 O O   . GLY C 1 381 ? 120.672 132.215 155.837 1.00 51.69  ? 381 GLY C O   1 
ATOM   10403 N N   . LYS C 1 382 ? 121.698 130.496 156.870 1.00 46.26  ? 382 LYS C N   1 
ATOM   10404 C CA  . LYS C 1 382 ? 122.986 131.179 156.923 1.00 46.26  ? 382 LYS C CA  1 
ATOM   10405 C C   . LYS C 1 382 ? 123.557 131.427 155.531 1.00 46.26  ? 382 LYS C C   1 
ATOM   10406 O O   . LYS C 1 382 ? 124.116 132.498 155.268 1.00 46.26  ? 382 LYS C O   1 
ATOM   10407 C CB  . LYS C 1 382 ? 123.964 130.373 157.777 1.00 46.26  ? 382 LYS C CB  1 
ATOM   10408 C CG  . LYS C 1 382 ? 125.323 131.016 157.935 1.00 46.26  ? 382 LYS C CG  1 
ATOM   10409 C CD  . LYS C 1 382 ? 126.225 130.189 158.831 1.00 46.26  ? 382 LYS C CD  1 
ATOM   10410 C CE  . LYS C 1 382 ? 125.959 130.493 160.293 1.00 46.26  ? 382 LYS C CE  1 
ATOM   10411 N NZ  . LYS C 1 382 ? 126.408 131.864 160.656 1.00 46.26  ? 382 LYS C NZ  1 
ATOM   10412 N N   . LEU C 1 383 ? 123.434 130.453 154.627 1.00 44.28  ? 383 LEU C N   1 
ATOM   10413 C CA  . LEU C 1 383 ? 124.050 130.579 153.311 1.00 44.28  ? 383 LEU C CA  1 
ATOM   10414 C C   . LEU C 1 383 ? 123.230 131.424 152.344 1.00 44.28  ? 383 LEU C C   1 
ATOM   10415 O O   . LEU C 1 383 ? 123.761 131.848 151.313 1.00 44.28  ? 383 LEU C O   1 
ATOM   10416 C CB  . LEU C 1 383 ? 124.286 129.195 152.703 1.00 44.28  ? 383 LEU C CB  1 
ATOM   10417 C CG  . LEU C 1 383 ? 125.530 129.063 151.822 1.00 44.28  ? 383 LEU C CG  1 
ATOM   10418 C CD1 . LEU C 1 383 ? 126.786 129.282 152.647 1.00 44.28  ? 383 LEU C CD1 1 
ATOM   10419 C CD2 . LEU C 1 383 ? 125.567 127.709 151.139 1.00 44.28  ? 383 LEU C CD2 1 
ATOM   10420 N N   . ASN C 1 384 ? 121.958 131.681 152.649 1.00 48.00  ? 384 ASN C N   1 
ATOM   10421 C CA  . ASN C 1 384 ? 121.126 132.492 151.768 1.00 48.00  ? 384 ASN C CA  1 
ATOM   10422 C C   . ASN C 1 384 ? 121.401 133.983 151.903 1.00 48.00  ? 384 ASN C C   1 
ATOM   10423 O O   . ASN C 1 384 ? 120.847 134.767 151.126 1.00 48.00  ? 384 ASN C O   1 
ATOM   10424 C CB  . ASN C 1 384 ? 119.646 132.216 152.037 1.00 48.00  ? 384 ASN C CB  1 
ATOM   10425 C CG  . ASN C 1 384 ? 119.338 130.735 152.134 1.00 48.00  ? 384 ASN C CG  1 
ATOM   10426 O OD1 . ASN C 1 384 ? 119.838 130.040 153.018 1.00 48.00  ? 384 ASN C OD1 1 
ATOM   10427 N ND2 . ASN C 1 384 ? 118.508 130.244 151.222 1.00 48.00  ? 384 ASN C ND2 1 
ATOM   10428 N N   . ARG C 1 385 ? 122.229 134.392 152.864 1.00 46.12  ? 385 ARG C N   1 
ATOM   10429 C CA  . ARG C 1 385 ? 122.537 135.805 153.044 1.00 46.12  ? 385 ARG C CA  1 
ATOM   10430 C C   . ARG C 1 385 ? 123.557 136.325 152.040 1.00 46.12  ? 385 ARG C C   1 
ATOM   10431 O O   . ARG C 1 385 ? 123.748 137.542 151.952 1.00 46.12  ? 385 ARG C O   1 
ATOM   10432 C CB  . ARG C 1 385 ? 123.052 136.058 154.462 1.00 46.12  ? 385 ARG C CB  1 
ATOM   10433 C CG  . ARG C 1 385 ? 121.960 136.265 155.495 1.00 46.12  ? 385 ARG C CG  1 
ATOM   10434 C CD  . ARG C 1 385 ? 122.393 135.765 156.861 1.00 46.12  ? 385 ARG C CD  1 
ATOM   10435 N NE  . ARG C 1 385 ? 121.266 135.281 157.649 1.00 46.12  ? 385 ARG C NE  1 
ATOM   10436 C CZ  . ARG C 1 385 ? 121.366 134.407 158.640 1.00 46.12  ? 385 ARG C CZ  1 
ATOM   10437 N NH1 . ARG C 1 385 ? 122.533 133.898 158.996 1.00 46.12  ? 385 ARG C NH1 1 
ATOM   10438 N NH2 . ARG C 1 385 ? 120.268 134.034 159.290 1.00 46.12  ? 385 ARG C NH2 1 
ATOM   10439 N N   . VAL C 1 386 ? 124.213 135.443 151.288 1.00 43.65  ? 386 VAL C N   1 
ATOM   10440 C CA  . VAL C 1 386 ? 125.280 135.859 150.384 1.00 43.65  ? 386 VAL C CA  1 
ATOM   10441 C C   . VAL C 1 386 ? 124.970 135.422 148.958 1.00 43.65  ? 386 VAL C C   1 
ATOM   10442 O O   . VAL C 1 386 ? 124.932 136.249 148.040 1.00 43.65  ? 386 VAL C O   1 
ATOM   10443 C CB  . VAL C 1 386 ? 126.640 135.302 150.843 1.00 43.65  ? 386 VAL C CB  1 
ATOM   10444 C CG1 . VAL C 1 386 ? 127.692 135.518 149.768 1.00 43.65  ? 386 VAL C CG1 1 
ATOM   10445 C CG2 . VAL C 1 386 ? 127.067 135.955 152.147 1.00 43.65  ? 386 VAL C CG2 1 
ATOM   10446 N N   . ILE C 1 387 ? 124.747 134.128 148.760 1.00 45.61  ? 387 ILE C N   1 
ATOM   10447 C CA  . ILE C 1 387 ? 124.542 133.587 147.421 1.00 45.61  ? 387 ILE C CA  1 
ATOM   10448 C C   . ILE C 1 387 ? 123.107 133.841 146.983 1.00 45.61  ? 387 ILE C C   1 
ATOM   10449 O O   . ILE C 1 387 ? 122.161 133.663 147.761 1.00 45.61  ? 387 ILE C O   1 
ATOM   10450 C CB  . ILE C 1 387 ? 124.873 132.084 147.386 1.00 45.61  ? 387 ILE C CB  1 
ATOM   10451 C CG1 . ILE C 1 387 ? 126.342 131.838 147.710 1.00 45.61  ? 387 ILE C CG1 1 
ATOM   10452 C CG2 . ILE C 1 387 ? 124.586 131.499 146.018 1.00 45.61  ? 387 ILE C CG2 1 
ATOM   10453 C CD1 . ILE C 1 387 ? 126.648 130.381 147.938 1.00 45.61  ? 387 ILE C CD1 1 
ATOM   10454 N N   . GLU C 1 388 ? 122.941 134.263 145.731 1.00 51.44  ? 388 GLU C N   1 
ATOM   10455 C CA  . GLU C 1 388 ? 121.615 134.370 145.141 1.00 51.44  ? 388 GLU C CA  1 
ATOM   10456 C C   . GLU C 1 388 ? 120.972 132.988 145.045 1.00 51.44  ? 388 GLU C C   1 
ATOM   10457 O O   . GLU C 1 388 ? 121.637 131.955 145.153 1.00 51.44  ? 388 GLU C O   1 
ATOM   10458 C CB  . GLU C 1 388 ? 121.695 135.016 143.758 1.00 51.44  ? 388 GLU C CB  1 
ATOM   10459 C CG  . GLU C 1 388 ? 122.168 136.464 143.764 1.00 51.44  ? 388 GLU C CG  1 
ATOM   10460 C CD  . GLU C 1 388 ? 123.681 136.593 143.798 1.00 51.44  ? 388 GLU C CD  1 
ATOM   10461 O OE1 . GLU C 1 388 ? 124.371 135.552 143.760 1.00 51.44  ? 388 GLU C OE1 1 
ATOM   10462 O OE2 . GLU C 1 388 ? 124.180 137.737 143.865 1.00 51.44  ? 388 GLU C OE2 1 
ATOM   10463 N N   . LYS C 1 389 ? 119.652 132.974 144.845 1.00 53.04  ? 389 LYS C N   1 
ATOM   10464 C CA  . LYS C 1 389 ? 118.922 131.709 144.851 1.00 53.04  ? 389 LYS C CA  1 
ATOM   10465 C C   . LYS C 1 389 ? 119.415 130.782 143.746 1.00 53.04  ? 389 LYS C C   1 
ATOM   10466 O O   . LYS C 1 389 ? 120.009 129.733 144.019 1.00 53.04  ? 389 LYS C O   1 
ATOM   10467 C CB  . LYS C 1 389 ? 117.421 131.968 144.713 1.00 53.04  ? 389 LYS C CB  1 
ATOM   10468 C CG  . LYS C 1 389 ? 116.556 130.811 145.187 1.00 53.04  ? 389 LYS C CG  1 
ATOM   10469 C CD  . LYS C 1 389 ? 115.108 131.236 145.363 1.00 53.04  ? 389 LYS C CD  1 
ATOM   10470 C CE  . LYS C 1 389 ? 114.287 130.131 146.005 1.00 53.04  ? 389 LYS C CE  1 
ATOM   10471 N NZ  . LYS C 1 389 ? 112.913 130.589 146.351 1.00 53.04  ? 389 LYS C NZ  1 
ATOM   10472 N N   . THR C 1 390 ? 119.196 131.164 142.489 1.00 48.26  ? 390 THR C N   1 
ATOM   10473 C CA  . THR C 1 390 ? 119.688 130.419 141.339 1.00 48.26  ? 390 THR C CA  1 
ATOM   10474 C C   . THR C 1 390 ? 119.999 131.390 140.213 1.00 48.26  ? 390 THR C C   1 
ATOM   10475 O O   . THR C 1 390 ? 119.380 132.453 140.112 1.00 48.26  ? 390 THR C O   1 
ATOM   10476 C CB  . THR C 1 390 ? 118.673 129.377 140.835 1.00 48.26  ? 390 THR C CB  1 
ATOM   10477 O OG1 . THR C 1 390 ? 117.362 129.956 140.794 1.00 48.26  ? 390 THR C OG1 1 
ATOM   10478 C CG2 . THR C 1 390 ? 118.664 128.132 141.714 1.00 48.26  ? 390 THR C CG2 1 
ATOM   10479 N N   . ASN C 1 391 ? 120.958 131.021 139.371 1.00 38.74  ? 391 ASN C N   1 
ATOM   10480 C CA  . ASN C 1 391 ? 121.247 131.748 138.141 1.00 38.74  ? 391 ASN C CA  1 
ATOM   10481 C C   . ASN C 1 391 ? 120.655 130.962 136.975 1.00 38.74  ? 391 ASN C C   1 
ATOM   10482 O O   . ASN C 1 391 ? 121.089 129.843 136.685 1.00 38.74  ? 391 ASN C O   1 
ATOM   10483 C CB  . ASN C 1 391 ? 122.749 131.976 137.972 1.00 38.74  ? 391 ASN C CB  1 
ATOM   10484 C CG  . ASN C 1 391 ? 123.570 130.721 138.214 1.00 38.74  ? 391 ASN C CG  1 
ATOM   10485 O OD1 . ASN C 1 391 ? 123.034 129.664 138.542 1.00 38.74  ? 391 ASN C OD1 1 
ATOM   10486 N ND2 . ASN C 1 391 ? 124.881 130.834 138.046 1.00 38.74  ? 391 ASN C ND2 1 
ATOM   10487 N N   . GLU C 1 392 ? 119.660 131.546 136.315 1.00 34.08  ? 392 GLU C N   1 
ATOM   10488 C CA  . GLU C 1 392 ? 118.944 130.888 135.229 1.00 34.08  ? 392 GLU C CA  1 
ATOM   10489 C C   . GLU C 1 392 ? 119.539 131.356 133.906 1.00 34.08  ? 392 GLU C C   1 
ATOM   10490 O O   . GLU C 1 392 ? 119.357 132.510 133.508 1.00 34.08  ? 392 GLU C O   1 
ATOM   10491 C CB  . GLU C 1 392 ? 117.449 131.188 135.306 1.00 34.08  ? 392 GLU C CB  1 
ATOM   10492 C CG  . GLU C 1 392 ? 116.587 130.219 134.521 1.00 34.08  ? 392 GLU C CG  1 
ATOM   10493 C CD  . GLU C 1 392 ? 115.109 130.390 134.803 1.00 34.08  ? 392 GLU C CD  1 
ATOM   10494 O OE1 . GLU C 1 392 ? 114.748 131.330 135.541 1.00 34.08  ? 392 GLU C OE1 1 
ATOM   10495 O OE2 . GLU C 1 392 ? 114.309 129.580 134.290 1.00 34.08  ? 392 GLU C OE2 1 
ATOM   10496 N N   . LYS C 1 393 ? 120.250 130.457 133.230 1.00 29.86  ? 393 LYS C N   1 
ATOM   10497 C CA  . LYS C 1 393 ? 120.917 130.753 131.971 1.00 29.86  ? 393 LYS C CA  1 
ATOM   10498 C C   . LYS C 1 393 ? 120.404 129.800 130.903 1.00 29.86  ? 393 LYS C C   1 
ATOM   10499 O O   . LYS C 1 393 ? 120.218 128.609 131.164 1.00 29.86  ? 393 LYS C O   1 
ATOM   10500 C CB  . LYS C 1 393 ? 122.439 130.624 132.108 1.00 29.86  ? 393 LYS C CB  1 
ATOM   10501 C CG  . LYS C 1 393 ? 122.998 131.226 133.386 1.00 29.86  ? 393 LYS C CG  1 
ATOM   10502 C CD  . LYS C 1 393 ? 123.442 132.661 133.172 1.00 29.86  ? 393 LYS C CD  1 
ATOM   10503 C CE  . LYS C 1 393 ? 123.748 133.348 134.491 1.00 29.86  ? 393 LYS C CE  1 
ATOM   10504 N NZ  . LYS C 1 393 ? 123.670 134.829 134.371 1.00 29.86  ? 393 LYS C NZ  1 
ATOM   10505 N N   . PHE C 1 394 ? 120.174 130.326 129.700 1.00 28.55  ? 394 PHE C N   1 
ATOM   10506 C CA  . PHE C 1 394 ? 119.547 129.554 128.636 1.00 28.55  ? 394 PHE C CA  1 
ATOM   10507 C C   . PHE C 1 394 ? 120.484 129.293 127.463 1.00 28.55  ? 394 PHE C C   1 
ATOM   10508 O O   . PHE C 1 394 ? 120.745 128.134 127.131 1.00 28.55  ? 394 PHE C O   1 
ATOM   10509 C CB  . PHE C 1 394 ? 118.282 130.280 128.164 1.00 28.55  ? 394 PHE C CB  1 
ATOM   10510 C CG  . PHE C 1 394 ? 117.315 130.582 129.271 1.00 28.55  ? 394 PHE C CG  1 
ATOM   10511 C CD1 . PHE C 1 394 ? 116.594 129.566 129.876 1.00 28.55  ? 394 PHE C CD1 1 
ATOM   10512 C CD2 . PHE C 1 394 ? 117.138 131.880 129.717 1.00 28.55  ? 394 PHE C CD2 1 
ATOM   10513 C CE1 . PHE C 1 394 ? 115.710 129.840 130.895 1.00 28.55  ? 394 PHE C CE1 1 
ATOM   10514 C CE2 . PHE C 1 394 ? 116.255 132.159 130.738 1.00 28.55  ? 394 PHE C CE2 1 
ATOM   10515 C CZ  . PHE C 1 394 ? 115.539 131.139 131.326 1.00 28.55  ? 394 PHE C CZ  1 
ATOM   10516 N N   . HIS C 1 395 ? 121.015 130.336 126.834 1.00 24.95  ? 395 HIS C N   1 
ATOM   10517 C CA  . HIS C 1 395 ? 121.896 130.189 125.683 1.00 24.95  ? 395 HIS C CA  1 
ATOM   10518 C C   . HIS C 1 395 ? 123.270 130.736 126.035 1.00 24.95  ? 395 HIS C C   1 
ATOM   10519 O O   . HIS C 1 395 ? 123.384 131.848 126.559 1.00 24.95  ? 395 HIS C O   1 
ATOM   10520 C CB  . HIS C 1 395 ? 121.334 130.909 124.454 1.00 24.95  ? 395 HIS C CB  1 
ATOM   10521 C CG  . HIS C 1 395 ? 121.973 130.492 123.166 1.00 24.95  ? 395 HIS C CG  1 
ATOM   10522 N ND1 . HIS C 1 395 ? 121.843 129.221 122.649 1.00 24.95  ? 395 HIS C ND1 1 
ATOM   10523 C CD2 . HIS C 1 395 ? 122.751 131.174 122.294 1.00 24.95  ? 395 HIS C CD2 1 
ATOM   10524 C CE1 . HIS C 1 395 ? 122.512 129.139 121.513 1.00 24.95  ? 395 HIS C CE1 1 
ATOM   10525 N NE2 . HIS C 1 395 ? 123.072 130.311 121.275 1.00 24.95  ? 395 HIS C NE2 1 
ATOM   10526 N N   . GLN C 1 396 ? 124.306 129.953 125.747 1.00 26.07  ? 396 GLN C N   1 
ATOM   10527 C CA  . GLN C 1 396 ? 125.674 130.308 126.094 1.00 26.07  ? 396 GLN C CA  1 
ATOM   10528 C C   . GLN C 1 396 ? 126.579 129.911 124.933 1.00 26.07  ? 396 GLN C C   1 
ATOM   10529 O O   . GLN C 1 396 ? 126.116 129.634 123.823 1.00 26.07  ? 396 GLN C O   1 
ATOM   10530 C CB  . GLN C 1 396 ? 126.090 129.640 127.411 1.00 26.07  ? 396 GLN C CB  1 
ATOM   10531 C CG  . GLN C 1 396 ? 125.392 130.201 128.640 1.00 26.07  ? 396 GLN C CG  1 
ATOM   10532 C CD  . GLN C 1 396 ? 125.139 129.151 129.699 1.00 26.07  ? 396 GLN C CD  1 
ATOM   10533 O OE1 . GLN C 1 396 ? 126.022 128.822 130.489 1.00 26.07  ? 396 GLN C OE1 1 
ATOM   10534 N NE2 . GLN C 1 396 ? 123.926 128.614 129.720 1.00 26.07  ? 396 GLN C NE2 1 
ATOM   10535 N N   . ILE C 1 397 ? 127.884 129.892 125.193 1.00 24.69  ? 397 ILE C N   1 
ATOM   10536 C CA  . ILE C 1 397 ? 128.875 129.526 124.189 1.00 24.69  ? 397 ILE C CA  1 
ATOM   10537 C C   . ILE C 1 397 ? 129.042 128.013 124.162 1.00 24.69  ? 397 ILE C C   1 
ATOM   10538 O O   . ILE C 1 397 ? 128.580 127.309 125.067 1.00 24.69  ? 397 ILE C O   1 
ATOM   10539 C CB  . ILE C 1 397 ? 130.222 130.220 124.461 1.00 24.69  ? 397 ILE C CB  1 
ATOM   10540 C CG1 . ILE C 1 397 ? 130.728 129.859 125.859 1.00 24.69  ? 397 ILE C CG1 1 
ATOM   10541 C CG2 . ILE C 1 397 ? 130.084 131.724 124.311 1.00 24.69  ? 397 ILE C CG2 1 
ATOM   10542 C CD1 . ILE C 1 397 ? 132.210 130.066 126.046 1.00 24.69  ? 397 ILE C CD1 1 
ATOM   10543 N N   . GLU C 1 398 ? 129.690 127.503 123.119 1.00 26.30  ? 398 GLU C N   1 
ATOM   10544 C CA  . GLU C 1 398 ? 130.037 126.091 123.057 1.00 26.30  ? 398 GLU C CA  1 
ATOM   10545 C C   . GLU C 1 398 ? 131.257 125.814 123.925 1.00 26.30  ? 398 GLU C C   1 
ATOM   10546 O O   . GLU C 1 398 ? 132.190 126.618 123.985 1.00 26.30  ? 398 GLU C O   1 
ATOM   10547 C CB  . GLU C 1 398 ? 130.312 125.667 121.614 1.00 26.30  ? 398 GLU C CB  1 
ATOM   10548 C CG  . GLU C 1 398 ? 129.128 125.834 120.680 1.00 26.30  ? 398 GLU C CG  1 
ATOM   10549 C CD  . GLU C 1 398 ? 127.958 124.950 121.055 1.00 26.30  ? 398 GLU C CD  1 
ATOM   10550 O OE1 . GLU C 1 398 ? 128.150 123.722 121.162 1.00 26.30  ? 398 GLU C OE1 1 
ATOM   10551 O OE2 . GLU C 1 398 ? 126.845 125.483 121.244 1.00 26.30  ? 398 GLU C OE2 1 
ATOM   10552 N N   . LYS C 1 399 ? 131.245 124.666 124.602 1.00 25.08  ? 399 LYS C N   1 
ATOM   10553 C CA  . LYS C 1 399 ? 132.304 124.311 125.534 1.00 25.08  ? 399 LYS C CA  1 
ATOM   10554 C C   . LYS C 1 399 ? 132.993 122.996 125.198 1.00 25.08  ? 399 LYS C C   1 
ATOM   10555 O O   . LYS C 1 399 ? 133.902 122.588 125.929 1.00 25.08  ? 399 LYS C O   1 
ATOM   10556 C CB  . LYS C 1 399 ? 131.749 124.254 126.963 1.00 25.08  ? 399 LYS C CB  1 
ATOM   10557 C CG  . LYS C 1 399 ? 131.400 125.620 127.524 1.00 25.08  ? 399 LYS C CG  1 
ATOM   10558 C CD  . LYS C 1 399 ? 130.396 125.528 128.651 1.00 25.08  ? 399 LYS C CD  1 
ATOM   10559 C CE  . LYS C 1 399 ? 129.832 126.897 128.986 1.00 25.08  ? 399 LYS C CE  1 
ATOM   10560 N NZ  . LYS C 1 399 ? 128.834 126.837 130.084 1.00 25.08  ? 399 LYS C NZ  1 
ATOM   10561 N N   . GLU C 1 400 ? 132.591 122.322 124.123 1.00 26.79  ? 400 GLU C N   1 
ATOM   10562 C CA  . GLU C 1 400 ? 133.253 121.112 123.662 1.00 26.79  ? 400 GLU C CA  1 
ATOM   10563 C C   . GLU C 1 400 ? 133.355 121.160 122.147 1.00 26.79  ? 400 GLU C C   1 
ATOM   10564 O O   . GLU C 1 400 ? 132.410 121.572 121.469 1.00 26.79  ? 400 GLU C O   1 
ATOM   10565 C CB  . GLU C 1 400 ? 132.502 119.851 124.106 1.00 26.79  ? 400 GLU C CB  1 
ATOM   10566 C CG  . GLU C 1 400 ? 132.818 119.410 125.524 1.00 26.79  ? 400 GLU C CG  1 
ATOM   10567 C CD  . GLU C 1 400 ? 132.171 118.089 125.881 1.00 26.79  ? 400 GLU C CD  1 
ATOM   10568 O OE1 . GLU C 1 400 ? 132.083 117.211 124.998 1.00 26.79  ? 400 GLU C OE1 1 
ATOM   10569 O OE2 . GLU C 1 400 ? 131.752 117.924 127.046 1.00 26.79  ? 400 GLU C OE2 1 
ATOM   10570 N N   . PHE C 1 401 ? 134.501 120.739 121.620 1.00 26.49  ? 401 PHE C N   1 
ATOM   10571 C CA  . PHE C 1 401 ? 134.791 120.850 120.198 1.00 26.49  ? 401 PHE C CA  1 
ATOM   10572 C C   . PHE C 1 401 ? 135.334 119.530 119.672 1.00 26.49  ? 401 PHE C C   1 
ATOM   10573 O O   . PHE C 1 401 ? 136.091 118.841 120.361 1.00 26.49  ? 401 PHE C O   1 
ATOM   10574 C CB  . PHE C 1 401 ? 135.795 121.978 119.929 1.00 26.49  ? 401 PHE C CB  1 
ATOM   10575 C CG  . PHE C 1 401 ? 135.457 123.266 120.625 1.00 26.49  ? 401 PHE C CG  1 
ATOM   10576 C CD1 . PHE C 1 401 ? 134.613 124.188 120.033 1.00 26.49  ? 401 PHE C CD1 1 
ATOM   10577 C CD2 . PHE C 1 401 ? 135.982 123.553 121.875 1.00 26.49  ? 401 PHE C CD2 1 
ATOM   10578 C CE1 . PHE C 1 401 ? 134.300 125.370 120.672 1.00 26.49  ? 401 PHE C CE1 1 
ATOM   10579 C CE2 . PHE C 1 401 ? 135.671 124.734 122.517 1.00 26.49  ? 401 PHE C CE2 1 
ATOM   10580 C CZ  . PHE C 1 401 ? 134.830 125.643 121.915 1.00 26.49  ? 401 PHE C CZ  1 
ATOM   10581 N N   . SER C 1 402 ? 134.941 119.184 118.446 1.00 31.13  ? 402 SER C N   1 
ATOM   10582 C CA  . SER C 1 402 ? 135.379 117.954 117.806 1.00 31.13  ? 402 SER C CA  1 
ATOM   10583 C C   . SER C 1 402 ? 136.432 118.171 116.729 1.00 31.13  ? 402 SER C C   1 
ATOM   10584 O O   . SER C 1 402 ? 136.930 117.190 116.168 1.00 31.13  ? 402 SER C O   1 
ATOM   10585 C CB  . SER C 1 402 ? 134.178 117.216 117.196 1.00 31.13  ? 402 SER C CB  1 
ATOM   10586 O OG  . SER C 1 402 ? 133.589 117.972 116.153 1.00 31.13  ? 402 SER C OG  1 
ATOM   10587 N N   . GLU C 1 403 ? 136.780 119.419 116.424 1.00 34.87  ? 403 GLU C N   1 
ATOM   10588 C CA  . GLU C 1 403 ? 137.789 119.728 115.424 1.00 34.87  ? 403 GLU C CA  1 
ATOM   10589 C C   . GLU C 1 403 ? 138.596 120.928 115.895 1.00 34.87  ? 403 GLU C C   1 
ATOM   10590 O O   . GLU C 1 403 ? 138.074 121.816 116.573 1.00 34.87  ? 403 GLU C O   1 
ATOM   10591 C CB  . GLU C 1 403 ? 137.146 120.009 114.055 1.00 34.87  ? 403 GLU C CB  1 
ATOM   10592 C CG  . GLU C 1 403 ? 138.131 120.301 112.930 1.00 34.87  ? 403 GLU C CG  1 
ATOM   10593 C CD  . GLU C 1 403 ? 139.014 119.114 112.593 1.00 34.87  ? 403 GLU C CD  1 
ATOM   10594 O OE1 . GLU C 1 403 ? 138.591 117.967 112.837 1.00 34.87  ? 403 GLU C OE1 1 
ATOM   10595 O OE2 . GLU C 1 403 ? 140.133 119.330 112.083 1.00 34.87  ? 403 GLU C OE2 1 
ATOM   10596 N N   . VAL C 1 404 ? 139.876 120.946 115.535 1.00 32.31  ? 404 VAL C N   1 
ATOM   10597 C CA  . VAL C 1 404 ? 140.758 122.045 115.912 1.00 32.31  ? 404 VAL C CA  1 
ATOM   10598 C C   . VAL C 1 404 ? 140.580 123.192 114.925 1.00 32.31  ? 404 VAL C C   1 
ATOM   10599 O O   . VAL C 1 404 ? 140.573 122.988 113.705 1.00 32.31  ? 404 VAL C O   1 
ATOM   10600 C CB  . VAL C 1 404 ? 142.221 121.576 115.979 1.00 32.31  ? 404 VAL C CB  1 
ATOM   10601 C CG1 . VAL C 1 404 ? 142.407 120.600 117.128 1.00 32.31  ? 404 VAL C CG1 1 
ATOM   10602 C CG2 . VAL C 1 404 ? 142.640 120.924 114.677 1.00 32.31  ? 404 VAL C CG2 1 
ATOM   10603 N N   . GLU C 1 405 ? 140.408 124.402 115.454 1.00 31.65  ? 405 GLU C N   1 
ATOM   10604 C CA  . GLU C 1 405 ? 140.207 125.592 114.638 1.00 31.65  ? 405 GLU C CA  1 
ATOM   10605 C C   . GLU C 1 405 ? 141.282 126.643 114.858 1.00 31.65  ? 405 GLU C C   1 
ATOM   10606 O O   . GLU C 1 405 ? 141.845 127.157 113.885 1.00 31.65  ? 405 GLU C O   1 
ATOM   10607 C CB  . GLU C 1 405 ? 138.821 126.191 114.916 1.00 31.65  ? 405 GLU C CB  1 
ATOM   10608 C CG  . GLU C 1 405 ? 137.680 125.204 114.759 1.00 31.65  ? 405 GLU C CG  1 
ATOM   10609 C CD  . GLU C 1 405 ? 136.341 125.800 115.136 1.00 31.65  ? 405 GLU C CD  1 
ATOM   10610 O OE1 . GLU C 1 405 ? 135.807 126.608 114.348 1.00 31.65  ? 405 GLU C OE1 1 
ATOM   10611 O OE2 . GLU C 1 405 ? 135.824 125.462 116.220 1.00 31.65  ? 405 GLU C OE2 1 
ATOM   10612 N N   . GLY C 1 406 ? 141.589 126.979 116.109 1.00 28.03  ? 406 GLY C N   1 
ATOM   10613 C CA  . GLY C 1 406 ? 142.613 127.968 116.379 1.00 28.03  ? 406 GLY C CA  1 
ATOM   10614 C C   . GLY C 1 406 ? 142.235 129.049 117.371 1.00 28.03  ? 406 GLY C C   1 
ATOM   10615 O O   . GLY C 1 406 ? 141.986 128.767 118.545 1.00 28.03  ? 406 GLY C O   1 
ATOM   10616 N N   . ARG C 1 407 ? 142.186 130.295 116.895 1.00 26.81  ? 407 ARG C N   1 
ATOM   10617 C CA  . ARG C 1 407 ? 142.140 131.458 117.779 1.00 26.81  ? 407 ARG C CA  1 
ATOM   10618 C C   . ARG C 1 407 ? 140.861 131.497 118.614 1.00 26.81  ? 407 ARG C C   1 
ATOM   10619 O O   . ARG C 1 407 ? 140.912 131.639 119.844 1.00 26.81  ? 407 ARG C O   1 
ATOM   10620 C CB  . ARG C 1 407 ? 142.277 132.727 116.936 1.00 26.81  ? 407 ARG C CB  1 
ATOM   10621 C CG  . ARG C 1 407 ? 143.060 133.855 117.573 1.00 26.81  ? 407 ARG C CG  1 
ATOM   10622 C CD  . ARG C 1 407 ? 143.228 134.997 116.586 1.00 26.81  ? 407 ARG C CD  1 
ATOM   10623 N NE  . ARG C 1 407 ? 143.566 136.255 117.240 1.00 26.81  ? 407 ARG C NE  1 
ATOM   10624 C CZ  . ARG C 1 407 ? 143.980 137.340 116.601 1.00 26.81  ? 407 ARG C CZ  1 
ATOM   10625 N NH1 . ARG C 1 407 ? 144.124 137.355 115.287 1.00 26.81  ? 407 ARG C NH1 1 
ATOM   10626 N NH2 . ARG C 1 407 ? 144.256 138.438 117.299 1.00 26.81  ? 407 ARG C NH2 1 
ATOM   10627 N N   . ILE C 1 408 ? 139.703 131.374 117.961 1.00 26.56  ? 408 ILE C N   1 
ATOM   10628 C CA  . ILE C 1 408 ? 138.430 131.558 118.655 1.00 26.56  ? 408 ILE C CA  1 
ATOM   10629 C C   . ILE C 1 408 ? 138.188 130.429 119.649 1.00 26.56  ? 408 ILE C C   1 
ATOM   10630 O O   . ILE C 1 408 ? 137.677 130.652 120.755 1.00 26.56  ? 408 ILE C O   1 
ATOM   10631 C CB  . ILE C 1 408 ? 137.283 131.674 117.637 1.00 26.56  ? 408 ILE C CB  1 
ATOM   10632 C CG1 . ILE C 1 408 ? 137.705 132.545 116.453 1.00 26.56  ? 408 ILE C CG1 1 
ATOM   10633 C CG2 . ILE C 1 408 ? 136.042 132.252 118.295 1.00 26.56  ? 408 ILE C CG2 1 
ATOM   10634 C CD1 . ILE C 1 408 ? 138.007 133.980 116.824 1.00 26.56  ? 408 ILE C CD1 1 
ATOM   10635 N N   . GLN C 1 409 ? 138.540 129.200 119.268 1.00 26.81  ? 409 GLN C N   1 
ATOM   10636 C CA  . GLN C 1 409 ? 138.392 128.066 120.173 1.00 26.81  ? 409 GLN C CA  1 
ATOM   10637 C C   . GLN C 1 409 ? 139.264 128.238 121.410 1.00 26.81  ? 409 GLN C C   1 
ATOM   10638 O O   . GLN C 1 409 ? 138.830 127.953 122.536 1.00 26.81  ? 409 GLN C O   1 
ATOM   10639 C CB  . GLN C 1 409 ? 138.740 126.776 119.433 1.00 26.81  ? 409 GLN C CB  1 
ATOM   10640 C CG  . GLN C 1 409 ? 138.435 125.503 120.187 1.00 26.81  ? 409 GLN C CG  1 
ATOM   10641 C CD  . GLN C 1 409 ? 138.644 124.270 119.333 1.00 26.81  ? 409 GLN C CD  1 
ATOM   10642 O OE1 . GLN C 1 409 ? 139.423 123.384 119.682 1.00 26.81  ? 409 GLN C OE1 1 
ATOM   10643 N NE2 . GLN C 1 409 ? 137.949 124.208 118.205 1.00 26.81  ? 409 GLN C NE2 1 
ATOM   10644 N N   . ASP C 1 410 ? 140.497 128.715 121.219 1.00 25.97  ? 410 ASP C N   1 
ATOM   10645 C CA  . ASP C 1 410 ? 141.378 128.988 122.348 1.00 25.97  ? 410 ASP C CA  1 
ATOM   10646 C C   . ASP C 1 410 ? 140.786 130.051 123.262 1.00 25.97  ? 410 ASP C C   1 
ATOM   10647 O O   . ASP C 1 410 ? 140.833 129.918 124.491 1.00 25.97  ? 410 ASP C O   1 
ATOM   10648 C CB  . ASP C 1 410 ? 142.752 129.427 121.845 1.00 25.97  ? 410 ASP C CB  1 
ATOM   10649 C CG  . ASP C 1 410 ? 143.470 128.335 121.085 1.00 25.97  ? 410 ASP C CG  1 
ATOM   10650 O OD1 . ASP C 1 410 ? 142.893 127.239 120.926 1.00 25.97  ? 410 ASP C OD1 1 
ATOM   10651 O OD2 . ASP C 1 410 ? 144.611 128.574 120.640 1.00 25.97  ? 410 ASP C OD2 1 
ATOM   10652 N N   . LEU C 1 411 ? 140.224 131.114 122.680 1.00 23.65  ? 411 LEU C N   1 
ATOM   10653 C CA  . LEU C 1 411 ? 139.618 132.162 123.497 1.00 23.65  ? 411 LEU C CA  1 
ATOM   10654 C C   . LEU C 1 411 ? 138.448 131.625 124.314 1.00 23.65  ? 411 LEU C C   1 
ATOM   10655 O O   . LEU C 1 411 ? 138.312 131.941 125.505 1.00 23.65  ? 411 LEU C O   1 
ATOM   10656 C CB  . LEU C 1 411 ? 139.167 133.320 122.607 1.00 23.65  ? 411 LEU C CB  1 
ATOM   10657 C CG  . LEU C 1 411 ? 138.884 134.653 123.300 1.00 23.65  ? 411 LEU C CG  1 
ATOM   10658 C CD1 . LEU C 1 411 ? 140.051 135.061 124.182 1.00 23.65  ? 411 LEU C CD1 1 
ATOM   10659 C CD2 . LEU C 1 411 ? 138.583 135.731 122.275 1.00 23.65  ? 411 LEU C CD2 1 
ATOM   10660 N N   . GLU C 1 412 ? 137.593 130.808 123.692 1.00 24.90  ? 412 GLU C N   1 
ATOM   10661 C CA  . GLU C 1 412 ? 136.450 130.247 124.407 1.00 24.90  ? 412 GLU C CA  1 
ATOM   10662 C C   . GLU C 1 412 ? 136.898 129.347 125.555 1.00 24.90  ? 412 GLU C C   1 
ATOM   10663 O O   . GLU C 1 412 ? 136.367 129.435 126.674 1.00 24.90  ? 412 GLU C O   1 
ATOM   10664 C CB  . GLU C 1 412 ? 135.560 129.475 123.435 1.00 24.90  ? 412 GLU C CB  1 
ATOM   10665 C CG  . GLU C 1 412 ? 134.603 130.353 122.651 1.00 24.90  ? 412 GLU C CG  1 
ATOM   10666 C CD  . GLU C 1 412 ? 134.188 129.736 121.333 1.00 24.90  ? 412 GLU C CD  1 
ATOM   10667 O OE1 . GLU C 1 412 ? 134.898 128.832 120.847 1.00 24.90  ? 412 GLU C OE1 1 
ATOM   10668 O OE2 . GLU C 1 412 ? 133.151 130.156 120.779 1.00 24.90  ? 412 GLU C OE2 1 
ATOM   10669 N N   . LYS C 1 413 ? 137.882 128.481 125.296 1.00 23.18  ? 413 LYS C N   1 
ATOM   10670 C CA  . LYS C 1 413 ? 138.393 127.607 126.346 1.00 23.18  ? 413 LYS C CA  1 
ATOM   10671 C C   . LYS C 1 413 ? 138.996 128.415 127.488 1.00 23.18  ? 413 LYS C C   1 
ATOM   10672 O O   . LYS C 1 413 ? 138.788 128.093 128.665 1.00 23.18  ? 413 LYS C O   1 
ATOM   10673 C CB  . LYS C 1 413 ? 139.427 126.646 125.764 1.00 23.18  ? 413 LYS C CB  1 
ATOM   10674 C CG  . LYS C 1 413 ? 138.834 125.519 124.943 1.00 23.18  ? 413 LYS C CG  1 
ATOM   10675 C CD  . LYS C 1 413 ? 139.907 124.806 124.143 1.00 23.18  ? 413 LYS C CD  1 
ATOM   10676 C CE  . LYS C 1 413 ? 139.401 123.487 123.591 1.00 23.18  ? 413 LYS C CE  1 
ATOM   10677 N NZ  . LYS C 1 413 ? 140.518 122.609 123.150 1.00 23.18  ? 413 LYS C NZ  1 
ATOM   10678 N N   . TYR C 1 414 ? 139.742 129.472 127.157 1.00 22.14  ? 414 TYR C N   1 
ATOM   10679 C CA  . TYR C 1 414 ? 140.343 130.322 128.180 1.00 22.14  ? 414 TYR C CA  1 
ATOM   10680 C C   . TYR C 1 414 ? 139.279 130.974 129.054 1.00 22.14  ? 414 TYR C C   1 
ATOM   10681 O O   . TYR C 1 414 ? 139.402 130.996 130.287 1.00 22.14  ? 414 TYR C O   1 
ATOM   10682 C CB  . TYR C 1 414 ? 141.214 131.382 127.505 1.00 22.14  ? 414 TYR C CB  1 
ATOM   10683 C CG  . TYR C 1 414 ? 142.156 132.112 128.431 1.00 22.14  ? 414 TYR C CG  1 
ATOM   10684 C CD1 . TYR C 1 414 ? 143.306 131.501 128.905 1.00 22.14  ? 414 TYR C CD1 1 
ATOM   10685 C CD2 . TYR C 1 414 ? 141.900 133.419 128.820 1.00 22.14  ? 414 TYR C CD2 1 
ATOM   10686 C CE1 . TYR C 1 414 ? 144.170 132.166 129.746 1.00 22.14  ? 414 TYR C CE1 1 
ATOM   10687 C CE2 . TYR C 1 414 ? 142.759 134.092 129.663 1.00 22.14  ? 414 TYR C CE2 1 
ATOM   10688 C CZ  . TYR C 1 414 ? 143.892 133.460 130.122 1.00 22.14  ? 414 TYR C CZ  1 
ATOM   10689 O OH  . TYR C 1 414 ? 144.752 134.127 130.960 1.00 22.14  ? 414 TYR C OH  1 
ATOM   10690 N N   . VAL C 1 415 ? 138.221 131.502 128.433 1.00 22.29  ? 415 VAL C N   1 
ATOM   10691 C CA  . VAL C 1 415 ? 137.162 132.164 129.192 1.00 22.29  ? 415 VAL C CA  1 
ATOM   10692 C C   . VAL C 1 415 ? 136.491 131.177 130.141 1.00 22.29  ? 415 VAL C C   1 
ATOM   10693 O O   . VAL C 1 415 ? 136.275 131.469 131.329 1.00 22.29  ? 415 VAL C O   1 
ATOM   10694 C CB  . VAL C 1 415 ? 136.144 132.810 128.235 1.00 22.29  ? 415 VAL C CB  1 
ATOM   10695 C CG1 . VAL C 1 415 ? 134.922 133.291 128.998 1.00 22.29  ? 415 VAL C CG1 1 
ATOM   10696 C CG2 . VAL C 1 415 ? 136.786 133.955 127.473 1.00 22.29  ? 415 VAL C CG2 1 
ATOM   10697 N N   . GLU C 1 416 ? 136.159 129.986 129.633 1.00 24.56  ? 416 GLU C N   1 
ATOM   10698 C CA  . GLU C 1 416 ? 135.486 129.000 130.474 1.00 24.56  ? 416 GLU C CA  1 
ATOM   10699 C C   . GLU C 1 416 ? 136.375 128.558 131.634 1.00 24.56  ? 416 GLU C C   1 
ATOM   10700 O O   . GLU C 1 416 ? 135.904 128.422 132.773 1.00 24.56  ? 416 GLU C O   1 
ATOM   10701 C CB  . GLU C 1 416 ? 135.052 127.800 129.633 1.00 24.56  ? 416 GLU C CB  1 
ATOM   10702 C CG  . GLU C 1 416 ? 134.106 126.845 130.347 1.00 24.56  ? 416 GLU C CG  1 
ATOM   10703 C CD  . GLU C 1 416 ? 132.922 127.550 130.983 1.00 24.56  ? 416 GLU C CD  1 
ATOM   10704 O OE1 . GLU C 1 416 ? 132.387 128.499 130.371 1.00 24.56  ? 416 GLU C OE1 1 
ATOM   10705 O OE2 . GLU C 1 416 ? 132.524 127.156 132.099 1.00 24.56  ? 416 GLU C OE2 1 
ATOM   10706 N N   . ASP C 1 417 ? 137.666 128.340 131.367 1.00 25.32  ? 417 ASP C N   1 
ATOM   10707 C CA  . ASP C 1 417 ? 138.579 127.915 132.423 1.00 25.32  ? 417 ASP C CA  1 
ATOM   10708 C C   . ASP C 1 417 ? 138.713 128.984 133.503 1.00 25.32  ? 417 ASP C C   1 
ATOM   10709 O O   . ASP C 1 417 ? 138.723 128.672 134.703 1.00 25.32  ? 417 ASP C O   1 
ATOM   10710 C CB  . ASP C 1 417 ? 139.943 127.578 131.820 1.00 25.32  ? 417 ASP C CB  1 
ATOM   10711 C CG  . ASP C 1 417 ? 140.739 126.619 132.677 1.00 25.32  ? 417 ASP C CG  1 
ATOM   10712 O OD1 . ASP C 1 417 ? 140.122 125.768 133.351 1.00 25.32  ? 417 ASP C OD1 1 
ATOM   10713 O OD2 . ASP C 1 417 ? 141.984 126.707 132.670 1.00 25.32  ? 417 ASP C OD2 1 
ATOM   10714 N N   . THR C 1 418 ? 138.810 130.253 133.095 1.00 22.04  ? 418 THR C N   1 
ATOM   10715 C CA  . THR C 1 418 ? 138.902 131.339 134.066 1.00 22.04  ? 418 THR C CA  1 
ATOM   10716 C C   . THR C 1 418 ? 137.661 131.388 134.950 1.00 22.04  ? 418 THR C C   1 
ATOM   10717 O O   . THR C 1 418 ? 137.759 131.523 136.180 1.00 22.04  ? 418 THR C O   1 
ATOM   10718 C CB  . THR C 1 418 ? 139.098 132.671 133.339 1.00 22.04  ? 418 THR C CB  1 
ATOM   10719 O OG1 . THR C 1 418 ? 140.247 132.588 132.487 1.00 22.04  ? 418 THR C OG1 1 
ATOM   10720 C CG2 . THR C 1 418 ? 139.298 133.800 134.334 1.00 22.04  ? 418 THR C CG2 1 
ATOM   10721 N N   . LYS C 1 419 ? 136.480 131.267 134.335 1.00 20.90  ? 419 LYS C N   1 
ATOM   10722 C CA  . LYS C 1 419 ? 135.238 131.292 135.105 1.00 20.90  ? 419 LYS C CA  1 
ATOM   10723 C C   . LYS C 1 419 ? 135.198 130.157 136.124 1.00 20.90  ? 419 LYS C C   1 
ATOM   10724 O O   . LYS C 1 419 ? 134.852 130.364 137.299 1.00 20.90  ? 419 LYS C O   1 
ATOM   10725 C CB  . LYS C 1 419 ? 134.045 131.210 134.152 1.00 20.90  ? 419 LYS C CB  1 
ATOM   10726 C CG  . LYS C 1 419 ? 132.701 131.016 134.823 1.00 20.90  ? 419 LYS C CG  1 
ATOM   10727 C CD  . LYS C 1 419 ? 131.597 130.919 133.786 1.00 20.90  ? 419 LYS C CD  1 
ATOM   10728 C CE  . LYS C 1 419 ? 130.247 131.291 134.368 1.00 20.90  ? 419 LYS C CE  1 
ATOM   10729 N NZ  . LYS C 1 419 ? 129.171 130.385 133.887 1.00 20.90  ? 419 LYS C NZ  1 
ATOM   10730 N N   . VAL C 1 420 ? 135.567 128.947 135.691 1.00 21.48  ? 420 VAL C N   1 
ATOM   10731 C CA  . VAL C 1 420 ? 135.517 127.791 136.583 1.00 21.48  ? 420 VAL C CA  1 
ATOM   10732 C C   . VAL C 1 420 ? 136.466 127.976 137.761 1.00 21.48  ? 420 VAL C C   1 
ATOM   10733 O O   . VAL C 1 420 ? 136.104 127.712 138.917 1.00 21.48  ? 420 VAL C O   1 
ATOM   10734 C CB  . VAL C 1 420 ? 135.826 126.500 135.802 1.00 21.48  ? 420 VAL C CB  1 
ATOM   10735 C CG1 . VAL C 1 420 ? 135.990 125.327 136.754 1.00 21.48  ? 420 VAL C CG1 1 
ATOM   10736 C CG2 . VAL C 1 420 ? 134.725 126.217 134.796 1.00 21.48  ? 420 VAL C CG2 1 
ATOM   10737 N N   . ASP C 1 421 ? 137.694 128.434 137.492 1.00 22.57  ? 421 ASP C N   1 
ATOM   10738 C CA  . ASP C 1 421 ? 138.661 128.611 138.572 1.00 22.57  ? 421 ASP C CA  1 
ATOM   10739 C C   . ASP C 1 421 ? 138.185 129.650 139.582 1.00 22.57  ? 421 ASP C C   1 
ATOM   10740 O O   . ASP C 1 421 ? 138.283 129.438 140.802 1.00 22.57  ? 421 ASP C O   1 
ATOM   10741 C CB  . ASP C 1 421 ? 140.020 129.010 137.998 1.00 22.57  ? 421 ASP C CB  1 
ATOM   10742 C CG  . ASP C 1 421 ? 140.746 127.847 137.358 1.00 22.57  ? 421 ASP C CG  1 
ATOM   10743 O OD1 . ASP C 1 421 ? 140.316 126.694 137.556 1.00 22.57  ? 421 ASP C OD1 1 
ATOM   10744 O OD2 . ASP C 1 421 ? 141.751 128.086 136.657 1.00 22.57  ? 421 ASP C OD2 1 
ATOM   10745 N N   . LEU C 1 422 ? 137.658 130.777 139.093 1.00 20.11  ? 422 LEU C N   1 
ATOM   10746 C CA  . LEU C 1 422 ? 137.209 131.823 140.006 1.00 20.11  ? 422 LEU C CA  1 
ATOM   10747 C C   . LEU C 1 422 ? 136.064 131.335 140.889 1.00 20.11  ? 422 LEU C C   1 
ATOM   10748 O O   . LEU C 1 422 ? 136.057 131.581 142.105 1.00 20.11  ? 422 LEU C O   1 
ATOM   10749 C CB  . LEU C 1 422 ? 136.798 133.066 139.216 1.00 20.11  ? 422 LEU C CB  1 
ATOM   10750 C CG  . LEU C 1 422 ? 137.953 133.957 138.747 1.00 20.11  ? 422 LEU C CG  1 
ATOM   10751 C CD1 . LEU C 1 422 ? 137.533 134.814 137.567 1.00 20.11  ? 422 LEU C CD1 1 
ATOM   10752 C CD2 . LEU C 1 422 ? 138.468 134.825 139.882 1.00 20.11  ? 422 LEU C CD2 1 
ATOM   10753 N N   . TRP C 1 423 ? 135.098 130.618 140.305 1.00 20.10  ? 423 TRP C N   1 
ATOM   10754 C CA  . TRP C 1 423 ? 133.976 130.160 141.120 1.00 20.10  ? 423 TRP C CA  1 
ATOM   10755 C C   . TRP C 1 423 ? 134.395 129.076 142.110 1.00 20.10  ? 423 TRP C C   1 
ATOM   10756 O O   . TRP C 1 423 ? 133.862 129.022 143.228 1.00 20.10  ? 423 TRP C O   1 
ATOM   10757 C CB  . TRP C 1 423 ? 132.833 129.679 140.230 1.00 20.10  ? 423 TRP C CB  1 
ATOM   10758 C CG  . TRP C 1 423 ? 131.941 130.805 139.799 1.00 20.10  ? 423 TRP C CG  1 
ATOM   10759 C CD1 . TRP C 1 423 ? 131.755 131.262 138.529 1.00 20.10  ? 423 TRP C CD1 1 
ATOM   10760 C CD2 . TRP C 1 423 ? 131.142 131.641 140.646 1.00 20.10  ? 423 TRP C CD2 1 
ATOM   10761 N NE1 . TRP C 1 423 ? 130.879 132.318 138.529 1.00 20.10  ? 423 TRP C NE1 1 
ATOM   10762 C CE2 . TRP C 1 423 ? 130.489 132.572 139.817 1.00 20.10  ? 423 TRP C CE2 1 
ATOM   10763 C CE3 . TRP C 1 423 ? 130.911 131.687 142.025 1.00 20.10  ? 423 TRP C CE3 1 
ATOM   10764 C CZ2 . TRP C 1 423 ? 129.620 133.538 140.319 1.00 20.10  ? 423 TRP C CZ2 1 
ATOM   10765 C CZ3 . TRP C 1 423 ? 130.049 132.647 142.521 1.00 20.10  ? 423 TRP C CZ3 1 
ATOM   10766 C CH2 . TRP C 1 423 ? 129.414 133.559 141.671 1.00 20.10  ? 423 TRP C CH2 1 
ATOM   10767 N N   . SER C 1 424 ? 135.350 128.218 141.735 1.00 21.06  ? 424 SER C N   1 
ATOM   10768 C CA  . SER C 1 424 ? 135.854 127.230 142.686 1.00 21.06  ? 424 SER C CA  1 
ATOM   10769 C C   . SER C 1 424 ? 136.510 127.903 143.886 1.00 21.06  ? 424 SER C C   1 
ATOM   10770 O O   . SER C 1 424 ? 136.275 127.509 145.042 1.00 21.06  ? 424 SER C O   1 
ATOM   10771 C CB  . SER C 1 424 ? 136.842 126.294 141.991 1.00 21.06  ? 424 SER C CB  1 
ATOM   10772 O OG  . SER C 1 424 ? 136.277 125.739 140.818 1.00 21.06  ? 424 SER C OG  1 
ATOM   10773 N N   . TYR C 1 425 ? 137.331 128.929 143.633 1.00 22.71  ? 425 TYR C N   1 
ATOM   10774 C CA  . TYR C 1 425 ? 137.939 129.662 144.741 1.00 22.71  ? 425 TYR C CA  1 
ATOM   10775 C C   . TYR C 1 425 ? 136.877 130.297 145.631 1.00 22.71  ? 425 TYR C C   1 
ATOM   10776 O O   . TYR C 1 425 ? 136.979 130.252 146.868 1.00 22.71  ? 425 TYR C O   1 
ATOM   10777 C CB  . TYR C 1 425 ? 138.898 130.726 144.208 1.00 22.71  ? 425 TYR C CB  1 
ATOM   10778 C CG  . TYR C 1 425 ? 139.420 131.660 145.277 1.00 22.71  ? 425 TYR C CG  1 
ATOM   10779 C CD1 . TYR C 1 425 ? 140.516 131.313 146.055 1.00 22.71  ? 425 TYR C CD1 1 
ATOM   10780 C CD2 . TYR C 1 425 ? 138.818 132.889 145.508 1.00 22.71  ? 425 TYR C CD2 1 
ATOM   10781 C CE1 . TYR C 1 425 ? 140.993 132.162 147.033 1.00 22.71  ? 425 TYR C CE1 1 
ATOM   10782 C CE2 . TYR C 1 425 ? 139.287 133.741 146.483 1.00 22.71  ? 425 TYR C CE2 1 
ATOM   10783 C CZ  . TYR C 1 425 ? 140.374 133.374 147.242 1.00 22.71  ? 425 TYR C CZ  1 
ATOM   10784 O OH  . TYR C 1 425 ? 140.843 134.226 148.213 1.00 22.71  ? 425 TYR C OH  1 
ATOM   10785 N N   . ASN C 1 426 ? 135.854 130.901 145.017 1.00 22.47  ? 426 ASN C N   1 
ATOM   10786 C CA  . ASN C 1 426 ? 134.793 131.535 145.796 1.00 22.47  ? 426 ASN C CA  1 
ATOM   10787 C C   . ASN C 1 426 ? 134.111 130.529 146.714 1.00 22.47  ? 426 ASN C C   1 
ATOM   10788 O O   . ASN C 1 426 ? 133.887 130.804 147.900 1.00 22.47  ? 426 ASN C O   1 
ATOM   10789 C CB  . ASN C 1 426 ? 133.768 132.181 144.864 1.00 22.47  ? 426 ASN C CB  1 
ATOM   10790 C CG  . ASN C 1 426 ? 134.231 133.513 144.320 1.00 22.47  ? 426 ASN C CG  1 
ATOM   10791 O OD1 . ASN C 1 426 ? 135.246 134.055 144.750 1.00 22.47  ? 426 ASN C OD1 1 
ATOM   10792 N ND2 . ASN C 1 426 ? 133.479 134.053 143.370 1.00 22.47  ? 426 ASN C ND2 1 
ATOM   10793 N N   . ALA C 1 427 ? 133.774 129.353 146.177 1.00 24.87  ? 427 ALA C N   1 
ATOM   10794 C CA  . ALA C 1 427 ? 133.092 128.339 146.976 1.00 24.87  ? 427 ALA C CA  1 
ATOM   10795 C C   . ALA C 1 427 ? 133.952 127.887 148.150 1.00 24.87  ? 427 ALA C C   1 
ATOM   10796 O O   . ALA C 1 427 ? 133.469 127.783 149.288 1.00 24.87  ? 427 ALA C O   1 
ATOM   10797 C CB  . ALA C 1 427 ? 132.714 127.148 146.097 1.00 24.87  ? 427 ALA C CB  1 
ATOM   10798 N N   . GLU C 1 428 ? 135.235 127.615 147.891 1.00 29.59  ? 428 GLU C N   1 
ATOM   10799 C CA  . GLU C 1 428 ? 136.127 127.171 148.962 1.00 29.59  ? 428 GLU C CA  1 
ATOM   10800 C C   . GLU C 1 428 ? 136.192 128.201 150.088 1.00 29.59  ? 428 GLU C C   1 
ATOM   10801 O O   . GLU C 1 428 ? 136.000 127.871 151.274 1.00 29.59  ? 428 GLU C O   1 
ATOM   10802 C CB  . GLU C 1 428 ? 137.521 126.908 148.390 1.00 29.59  ? 428 GLU C CB  1 
ATOM   10803 C CG  . GLU C 1 428 ? 138.515 126.298 149.364 1.00 29.59  ? 428 GLU C CG  1 
ATOM   10804 C CD  . GLU C 1 428 ? 138.209 124.849 149.683 1.00 29.59  ? 428 GLU C CD  1 
ATOM   10805 O OE1 . GLU C 1 428 ? 137.596 124.169 148.835 1.00 29.59  ? 428 GLU C OE1 1 
ATOM   10806 O OE2 . GLU C 1 428 ? 138.584 124.388 150.781 1.00 29.59  ? 428 GLU C OE2 1 
ATOM   10807 N N   . LEU C 1 429 ? 136.449 129.464 149.730 1.00 28.44  ? 429 LEU C N   1 
ATOM   10808 C CA  . LEU C 1 429 ? 136.593 130.501 150.748 1.00 28.44  ? 429 LEU C CA  1 
ATOM   10809 C C   . LEU C 1 429 ? 135.301 130.692 151.534 1.00 28.44  ? 429 LEU C C   1 
ATOM   10810 O O   . LEU C 1 429 ? 135.329 130.836 152.765 1.00 28.44  ? 429 LEU C O   1 
ATOM   10811 C CB  . LEU C 1 429 ? 137.029 131.816 150.103 1.00 28.44  ? 429 LEU C CB  1 
ATOM   10812 C CG  . LEU C 1 429 ? 137.150 133.012 151.049 1.00 28.44  ? 429 LEU C CG  1 
ATOM   10813 C CD1 . LEU C 1 429 ? 138.263 132.788 152.060 1.00 28.44  ? 429 LEU C CD1 1 
ATOM   10814 C CD2 . LEU C 1 429 ? 137.381 134.292 150.271 1.00 28.44  ? 429 LEU C CD2 1 
ATOM   10815 N N   . LEU C 1 430 ? 134.157 130.699 150.842 1.00 29.11  ? 430 LEU C N   1 
ATOM   10816 C CA  . LEU C 1 430 ? 132.890 130.900 151.535 1.00 29.11  ? 430 LEU C CA  1 
ATOM   10817 C C   . LEU C 1 430 ? 132.614 129.777 152.525 1.00 29.11  ? 430 LEU C C   1 
ATOM   10818 O O   . LEU C 1 430 ? 132.177 130.033 153.654 1.00 29.11  ? 430 LEU C O   1 
ATOM   10819 C CB  . LEU C 1 430 ? 131.747 131.011 150.530 1.00 29.11  ? 430 LEU C CB  1 
ATOM   10820 C CG  . LEU C 1 430 ? 130.372 131.162 151.179 1.00 29.11  ? 430 LEU C CG  1 
ATOM   10821 C CD1 . LEU C 1 430 ? 130.240 132.519 151.853 1.00 29.11  ? 430 LEU C CD1 1 
ATOM   10822 C CD2 . LEU C 1 430 ? 129.280 130.963 150.160 1.00 29.11  ? 430 LEU C CD2 1 
ATOM   10823 N N   . VAL C 1 431 ? 132.858 128.526 152.124 1.00 29.17  ? 431 VAL C N   1 
ATOM   10824 C CA  . VAL C 1 431 ? 132.598 127.412 153.032 1.00 29.17  ? 431 VAL C CA  1 
ATOM   10825 C C   . VAL C 1 431 ? 133.469 127.526 154.278 1.00 29.17  ? 431 VAL C C   1 
ATOM   10826 O O   . VAL C 1 431 ? 132.989 127.351 155.411 1.00 29.17  ? 431 VAL C O   1 
ATOM   10827 C CB  . VAL C 1 431 ? 132.805 126.069 152.309 1.00 29.17  ? 431 VAL C CB  1 
ATOM   10828 C CG1 . VAL C 1 431 ? 132.799 124.922 153.303 1.00 29.17  ? 431 VAL C CG1 1 
ATOM   10829 C CG2 . VAL C 1 431 ? 131.725 125.864 151.261 1.00 29.17  ? 431 VAL C CG2 1 
ATOM   10830 N N   . ALA C 1 432 ? 134.756 127.843 154.094 1.00 31.51  ? 432 ALA C N   1 
ATOM   10831 C CA  . ALA C 1 432 ? 135.641 127.977 155.251 1.00 31.51  ? 432 ALA C CA  1 
ATOM   10832 C C   . ALA C 1 432 ? 135.162 129.079 156.193 1.00 31.51  ? 432 ALA C C   1 
ATOM   10833 O O   . ALA C 1 432 ? 135.102 128.889 157.420 1.00 31.51  ? 432 ALA C O   1 
ATOM   10834 C CB  . ALA C 1 432 ? 137.072 128.246 154.786 1.00 31.51  ? 432 ALA C CB  1 
ATOM   10835 N N   . LEU C 1 433 ? 134.802 130.240 155.633 1.00 32.24  ? 433 LEU C N   1 
ATOM   10836 C CA  . LEU C 1 433 ? 134.361 131.359 156.462 1.00 32.24  ? 433 LEU C CA  1 
ATOM   10837 C C   . LEU C 1 433 ? 133.097 131.017 157.242 1.00 32.24  ? 433 LEU C C   1 
ATOM   10838 O O   . LEU C 1 433 ? 132.989 131.328 158.437 1.00 32.24  ? 433 LEU C O   1 
ATOM   10839 C CB  . LEU C 1 433 ? 134.126 132.593 155.591 1.00 32.24  ? 433 LEU C CB  1 
ATOM   10840 C CG  . LEU C 1 433 ? 135.291 133.561 155.395 1.00 32.24  ? 433 LEU C CG  1 
ATOM   10841 C CD1 . LEU C 1 433 ? 134.871 134.699 154.484 1.00 32.24  ? 433 LEU C CD1 1 
ATOM   10842 C CD2 . LEU C 1 433 ? 135.783 134.094 156.729 1.00 32.24  ? 433 LEU C CD2 1 
ATOM   10843 N N   . GLU C 1 434 ? 132.122 130.387 156.579 1.00 35.60  ? 434 GLU C N   1 
ATOM   10844 C CA  . GLU C 1 434 ? 130.873 130.061 157.259 1.00 35.60  ? 434 GLU C CA  1 
ATOM   10845 C C   . GLU C 1 434 ? 131.097 129.058 158.382 1.00 35.60  ? 434 GLU C C   1 
ATOM   10846 O O   . GLU C 1 434 ? 130.502 129.188 159.461 1.00 35.60  ? 434 GLU C O   1 
ATOM   10847 C CB  . GLU C 1 434 ? 129.841 129.532 156.264 1.00 35.60  ? 434 GLU C CB  1 
ATOM   10848 C CG  . GLU C 1 434 ? 129.531 130.475 155.115 1.00 35.60  ? 434 GLU C CG  1 
ATOM   10849 C CD  . GLU C 1 434 ? 128.747 131.695 155.549 1.00 35.60  ? 434 GLU C CD  1 
ATOM   10850 O OE1 . GLU C 1 434 ? 128.075 131.631 156.596 1.00 35.60  ? 434 GLU C OE1 1 
ATOM   10851 O OE2 . GLU C 1 434 ? 128.800 132.721 154.841 1.00 35.60  ? 434 GLU C OE2 1 
ATOM   10852 N N   . ASN C 1 435 ? 131.945 128.049 158.156 1.00 33.92  ? 435 ASN C N   1 
ATOM   10853 C CA  . ASN C 1 435 ? 132.221 127.092 159.225 1.00 33.92  ? 435 ASN C CA  1 
ATOM   10854 C C   . ASN C 1 435 ? 132.869 127.777 160.423 1.00 33.92  ? 435 ASN C C   1 
ATOM   10855 O O   . ASN C 1 435 ? 132.485 127.530 161.580 1.00 33.92  ? 435 ASN C O   1 
ATOM   10856 C CB  . ASN C 1 435 ? 133.111 125.965 158.704 1.00 33.92  ? 435 ASN C CB  1 
ATOM   10857 C CG  . ASN C 1 435 ? 132.362 125.000 157.813 1.00 33.92  ? 435 ASN C CG  1 
ATOM   10858 O OD1 . ASN C 1 435 ? 131.142 125.074 157.690 1.00 33.92  ? 435 ASN C OD1 1 
ATOM   10859 N ND2 . ASN C 1 435 ? 133.090 124.086 157.187 1.00 33.92  ? 435 ASN C ND2 1 
ATOM   10860 N N   . GLN C 1 436 ? 133.844 128.654 160.163 1.00 37.41  ? 436 GLN C N   1 
ATOM   10861 C CA  . GLN C 1 436 ? 134.506 129.364 161.254 1.00 37.41  ? 436 GLN C CA  1 
ATOM   10862 C C   . GLN C 1 436 ? 133.507 130.189 162.058 1.00 37.41  ? 436 GLN C C   1 
ATOM   10863 O O   . GLN C 1 436 ? 133.507 130.159 163.298 1.00 37.41  ? 436 GLN C O   1 
ATOM   10864 C CB  . GLN C 1 436 ? 135.617 130.253 160.694 1.00 37.41  ? 436 GLN C CB  1 
ATOM   10865 C CG  . GLN C 1 436 ? 136.290 131.144 161.722 1.00 37.41  ? 436 GLN C CG  1 
ATOM   10866 C CD  . GLN C 1 436 ? 137.411 130.441 162.459 1.00 37.41  ? 436 GLN C CD  1 
ATOM   10867 O OE1 . GLN C 1 436 ? 137.999 129.488 161.953 1.00 37.41  ? 436 GLN C OE1 1 
ATOM   10868 N NE2 . GLN C 1 436 ? 137.712 130.909 163.663 1.00 37.41  ? 436 GLN C NE2 1 
ATOM   10869 N N   . HIS C 1 437 ? 132.627 130.918 161.366 1.00 39.87  ? 437 HIS C N   1 
ATOM   10870 C CA  . HIS C 1 437 ? 131.676 131.768 162.074 1.00 39.87  ? 437 HIS C CA  1 
ATOM   10871 C C   . HIS C 1 437 ? 130.647 130.955 162.852 1.00 39.87  ? 437 HIS C C   1 
ATOM   10872 O O   . HIS C 1 437 ? 130.242 131.365 163.945 1.00 39.87  ? 437 HIS C O   1 
ATOM   10873 C CB  . HIS C 1 437 ? 130.990 132.720 161.098 1.00 39.87  ? 437 HIS C CB  1 
ATOM   10874 C CG  . HIS C 1 437 ? 131.773 133.968 160.832 1.00 39.87  ? 437 HIS C CG  1 
ATOM   10875 N ND1 . HIS C 1 437 ? 131.734 135.062 161.668 1.00 39.87  ? 437 HIS C ND1 1 
ATOM   10876 C CD2 . HIS C 1 437 ? 132.625 134.290 159.831 1.00 39.87  ? 437 HIS C CD2 1 
ATOM   10877 C CE1 . HIS C 1 437 ? 132.524 136.007 161.191 1.00 39.87  ? 437 HIS C CE1 1 
ATOM   10878 N NE2 . HIS C 1 437 ? 133.077 135.564 160.077 1.00 39.87  ? 437 HIS C NE2 1 
ATOM   10879 N N   . THR C 1 438 ? 130.215 129.809 162.319 1.00 39.69  ? 438 THR C N   1 
ATOM   10880 C CA  . THR C 1 438 ? 129.289 128.957 163.063 1.00 39.69  ? 438 THR C CA  1 
ATOM   10881 C C   . THR C 1 438 ? 129.916 128.474 164.366 1.00 39.69  ? 438 THR C C   1 
ATOM   10882 O O   . THR C 1 438 ? 129.294 128.543 165.439 1.00 39.69  ? 438 THR C O   1 
ATOM   10883 C CB  . THR C 1 438 ? 128.863 127.767 162.202 1.00 39.69  ? 438 THR C CB  1 
ATOM   10884 O OG1 . THR C 1 438 ? 128.108 128.234 161.078 1.00 39.69  ? 438 THR C OG1 1 
ATOM   10885 C CG2 . THR C 1 438 ? 128.011 126.801 163.009 1.00 39.69  ? 438 THR C CG2 1 
ATOM   10886 N N   . ILE C 1 439 ? 131.160 127.988 164.292 1.00 40.19  ? 439 ILE C N   1 
ATOM   10887 C CA  . ILE C 1 439 ? 131.826 127.513 165.504 1.00 40.19  ? 439 ILE C CA  1 
ATOM   10888 C C   . ILE C 1 439 ? 131.963 128.647 166.514 1.00 40.19  ? 439 ILE C C   1 
ATOM   10889 O O   . ILE C 1 439 ? 131.686 128.476 167.714 1.00 40.19  ? 439 ILE C O   1 
ATOM   10890 C CB  . ILE C 1 439 ? 133.192 126.893 165.156 1.00 40.19  ? 439 ILE C CB  1 
ATOM   10891 C CG1 . ILE C 1 439 ? 133.011 125.688 164.233 1.00 40.19  ? 439 ILE C CG1 1 
ATOM   10892 C CG2 . ILE C 1 439 ? 133.935 126.492 166.420 1.00 40.19  ? 439 ILE C CG2 1 
ATOM   10893 C CD1 . ILE C 1 439 ? 132.099 124.624 164.794 1.00 40.19  ? 439 ILE C CD1 1 
ATOM   10894 N N   . ASP C 1 440 ? 132.380 129.828 166.042 1.00 43.58  ? 440 ASP C N   1 
ATOM   10895 C CA  . ASP C 1 440 ? 132.563 130.959 166.944 1.00 43.58  ? 440 ASP C CA  1 
ATOM   10896 C C   . ASP C 1 440 ? 131.256 131.354 167.622 1.00 43.58  ? 440 ASP C C   1 
ATOM   10897 O O   . ASP C 1 440 ? 131.230 131.600 168.835 1.00 43.58  ? 440 ASP C O   1 
ATOM   10898 C CB  . ASP C 1 440 ? 133.151 132.146 166.181 1.00 43.58  ? 440 ASP C CB  1 
ATOM   10899 C CG  . ASP C 1 440 ? 134.661 132.075 166.068 1.00 43.58  ? 440 ASP C CG  1 
ATOM   10900 O OD1 . ASP C 1 440 ? 135.231 131.002 166.359 1.00 43.58  ? 440 ASP C OD1 1 
ATOM   10901 O OD2 . ASP C 1 440 ? 135.279 133.092 165.688 1.00 43.58  ? 440 ASP C OD2 1 
ATOM   10902 N N   . LEU C 1 441 ? 130.159 131.419 166.861 1.00 44.27  ? 441 LEU C N   1 
ATOM   10903 C CA  . LEU C 1 441 ? 128.897 131.856 167.451 1.00 44.27  ? 441 LEU C CA  1 
ATOM   10904 C C   . LEU C 1 441 ? 128.386 130.846 168.471 1.00 44.27  ? 441 LEU C C   1 
ATOM   10905 O O   . LEU C 1 441 ? 127.849 131.234 169.515 1.00 44.27  ? 441 LEU C O   1 
ATOM   10906 C CB  . LEU C 1 441 ? 127.848 132.123 166.365 1.00 44.27  ? 441 LEU C CB  1 
ATOM   10907 C CG  . LEU C 1 441 ? 127.310 131.051 165.412 1.00 44.27  ? 441 LEU C CG  1 
ATOM   10908 C CD1 . LEU C 1 441 ? 126.172 130.251 166.037 1.00 44.27  ? 441 LEU C CD1 1 
ATOM   10909 C CD2 . LEU C 1 441 ? 126.855 131.683 164.107 1.00 44.27  ? 441 LEU C CD2 1 
ATOM   10910 N N   . THR C 1 442 ? 128.547 129.548 168.200 1.00 46.40  ? 442 THR C N   1 
ATOM   10911 C CA  . THR C 1 442 ? 128.088 128.562 169.177 1.00 46.40  ? 442 THR C CA  1 
ATOM   10912 C C   . THR C 1 442 ? 128.904 128.630 170.468 1.00 46.40  ? 442 THR C C   1 
ATOM   10913 O O   . THR C 1 442 ? 128.344 128.555 171.577 1.00 46.40  ? 442 THR C O   1 
ATOM   10914 C CB  . THR C 1 442 ? 128.142 127.160 168.582 1.00 46.40  ? 442 THR C CB  1 
ATOM   10915 O OG1 . THR C 1 442 ? 127.623 127.187 167.247 1.00 46.40  ? 442 THR C OG1 1 
ATOM   10916 C CG2 . THR C 1 442 ? 127.295 126.230 169.409 1.00 46.40  ? 442 THR C CG2 1 
ATOM   10917 N N   . ASP C 1 443 ? 130.229 128.776 170.348 1.00 50.25  ? 443 ASP C N   1 
ATOM   10918 C CA  . ASP C 1 443 ? 131.051 128.913 171.547 1.00 50.25  ? 443 ASP C CA  1 
ATOM   10919 C C   . ASP C 1 443 ? 130.665 130.158 172.338 1.00 50.25  ? 443 ASP C C   1 
ATOM   10920 O O   . ASP C 1 443 ? 130.591 130.123 173.576 1.00 50.25  ? 443 ASP C O   1 
ATOM   10921 C CB  . ASP C 1 443 ? 132.531 128.952 171.169 1.00 50.25  ? 443 ASP C CB  1 
ATOM   10922 C CG  . ASP C 1 443 ? 133.089 127.579 170.856 1.00 50.25  ? 443 ASP C CG  1 
ATOM   10923 O OD1 . ASP C 1 443 ? 132.311 126.603 170.863 1.00 50.25  ? 443 ASP C OD1 1 
ATOM   10924 O OD2 . ASP C 1 443 ? 134.307 127.473 170.605 1.00 50.25  ? 443 ASP C OD2 1 
ATOM   10925 N N   . SER C 1 444 ? 130.410 131.268 171.638 1.00 52.11  ? 444 SER C N   1 
ATOM   10926 C CA  . SER C 1 444 ? 129.993 132.490 172.316 1.00 52.11  ? 444 SER C CA  1 
ATOM   10927 C C   . SER C 1 444 ? 128.659 132.300 173.024 1.00 52.11  ? 444 SER C C   1 
ATOM   10928 O O   . SER C 1 444 ? 128.455 132.827 174.120 1.00 52.11  ? 444 SER C O   1 
ATOM   10929 C CB  . SER C 1 444 ? 129.909 133.646 171.322 1.00 52.11  ? 444 SER C CB  1 
ATOM   10930 O OG  . SER C 1 444 ? 128.878 133.428 170.377 1.00 52.11  ? 444 SER C OG  1 
ATOM   10931 N N   . GLU C 1 445 ? 127.736 131.557 172.409 1.00 57.08  ? 445 GLU C N   1 
ATOM   10932 C CA  . GLU C 1 445 ? 126.450 131.292 173.051 1.00 57.08  ? 445 GLU C CA  1 
ATOM   10933 C C   . GLU C 1 445 ? 126.634 130.539 174.364 1.00 57.08  ? 445 GLU C C   1 
ATOM   10934 O O   . GLU C 1 445 ? 126.043 130.900 175.393 1.00 57.08  ? 445 GLU C O   1 
ATOM   10935 C CB  . GLU C 1 445 ? 125.547 130.504 172.102 1.00 57.08  ? 445 GLU C CB  1 
ATOM   10936 C CG  . GLU C 1 445 ? 124.070 130.560 172.453 1.00 57.08  ? 445 GLU C CG  1 
ATOM   10937 C CD  . GLU C 1 445 ? 123.460 131.923 172.201 1.00 57.08  ? 445 GLU C CD  1 
ATOM   10938 O OE1 . GLU C 1 445 ? 123.683 132.483 171.108 1.00 57.08  ? 445 GLU C OE1 1 
ATOM   10939 O OE2 . GLU C 1 445 ? 122.755 132.434 173.097 1.00 57.08  ? 445 GLU C OE2 1 
ATOM   10940 N N   . MET C 1 446 ? 127.456 129.487 174.347 1.00 58.49  ? 446 MET C N   1 
ATOM   10941 C CA  . MET C 1 446 ? 127.680 128.722 175.575 1.00 58.49  ? 446 MET C CA  1 
ATOM   10942 C C   . MET C 1 446 ? 128.323 129.589 176.657 1.00 58.49  ? 446 MET C C   1 
ATOM   10943 O O   . MET C 1 446 ? 127.885 129.590 177.820 1.00 58.49  ? 446 MET C O   1 
ATOM   10944 C CB  . MET C 1 446 ? 128.545 127.496 175.283 1.00 58.49  ? 446 MET C CB  1 
ATOM   10945 C CG  . MET C 1 446 ? 128.896 126.668 176.513 1.00 58.49  ? 446 MET C CG  1 
ATOM   10946 S SD  . MET C 1 446 ? 127.613 125.494 176.997 1.00 58.49  ? 446 MET C SD  1 
ATOM   10947 C CE  . MET C 1 446 ? 126.736 126.423 178.253 1.00 58.49  ? 446 MET C CE  1 
ATOM   10948 N N   . ASN C 1 447 ? 129.360 130.347 176.286 1.00 60.49  ? 447 ASN C N   1 
ATOM   10949 C CA  . ASN C 1 447 ? 130.040 131.184 177.269 1.00 60.49  ? 447 ASN C CA  1 
ATOM   10950 C C   . ASN C 1 447 ? 129.125 132.276 177.807 1.00 60.49  ? 447 ASN C C   1 
ATOM   10951 O O   . ASN C 1 447 ? 129.198 132.618 178.992 1.00 60.49  ? 447 ASN C O   1 
ATOM   10952 C CB  . ASN C 1 447 ? 131.302 131.794 176.662 1.00 60.49  ? 447 ASN C CB  1 
ATOM   10953 C CG  . ASN C 1 447 ? 132.475 130.835 176.680 1.00 60.49  ? 447 ASN C CG  1 
ATOM   10954 O OD1 . ASN C 1 447 ? 133.039 130.508 175.637 1.00 60.49  ? 447 ASN C OD1 1 
ATOM   10955 N ND2 . ASN C 1 447 ? 132.845 130.376 177.868 1.00 60.49  ? 447 ASN C ND2 1 
ATOM   10956 N N   . LYS C 1 448 ? 128.251 132.825 176.962 1.00 62.68  ? 448 LYS C N   1 
ATOM   10957 C CA  . LYS C 1 448 ? 127.324 133.858 177.408 1.00 62.68  ? 448 LYS C CA  1 
ATOM   10958 C C   . LYS C 1 448 ? 126.298 133.296 178.382 1.00 62.68  ? 448 LYS C C   1 
ATOM   10959 O O   . LYS C 1 448 ? 125.952 133.952 179.372 1.00 62.68  ? 448 LYS C O   1 
ATOM   10960 C CB  . LYS C 1 448 ? 126.633 134.488 176.201 1.00 62.68  ? 448 LYS C CB  1 
ATOM   10961 C CG  . LYS C 1 448 ? 125.673 135.606 176.544 1.00 62.68  ? 448 LYS C CG  1 
ATOM   10962 C CD  . LYS C 1 448 ? 125.132 136.261 175.286 1.00 62.68  ? 448 LYS C CD  1 
ATOM   10963 C CE  . LYS C 1 448 ? 124.132 135.357 174.588 1.00 62.68  ? 448 LYS C CE  1 
ATOM   10964 N NZ  . LYS C 1 448 ? 123.504 136.027 173.418 1.00 62.68  ? 448 LYS C NZ  1 
ATOM   10965 N N   . LEU C 1 449 ? 125.794 132.087 178.117 1.00 64.65  ? 449 LEU C N   1 
ATOM   10966 C CA  . LEU C 1 449 ? 124.880 131.464 179.071 1.00 64.65  ? 449 LEU C CA  1 
ATOM   10967 C C   . LEU C 1 449 ? 125.557 131.252 180.419 1.00 64.65  ? 449 LEU C C   1 
ATOM   10968 O O   . LEU C 1 449 ? 124.977 131.556 181.472 1.00 64.65  ? 449 LEU C O   1 
ATOM   10969 C CB  . LEU C 1 449 ? 124.357 130.137 178.522 1.00 64.65  ? 449 LEU C CB  1 
ATOM   10970 C CG  . LEU C 1 449 ? 123.396 129.382 179.445 1.00 64.65  ? 449 LEU C CG  1 
ATOM   10971 C CD1 . LEU C 1 449 ? 122.146 130.204 179.719 1.00 64.65  ? 449 LEU C CD1 1 
ATOM   10972 C CD2 . LEU C 1 449 ? 123.032 128.024 178.866 1.00 64.65  ? 449 LEU C CD2 1 
ATOM   10973 N N   . PHE C 1 450 ? 126.797 130.749 180.407 1.00 68.00  ? 450 PHE C N   1 
ATOM   10974 C CA  . PHE C 1 450 ? 127.506 130.558 181.671 1.00 68.00  ? 450 PHE C CA  1 
ATOM   10975 C C   . PHE C 1 450 ? 127.731 131.883 182.391 1.00 68.00  ? 450 PHE C C   1 
ATOM   10976 O O   . PHE C 1 450 ? 127.585 131.965 183.618 1.00 68.00  ? 450 PHE C O   1 
ATOM   10977 C CB  . PHE C 1 450 ? 128.839 129.849 181.440 1.00 68.00  ? 450 PHE C CB  1 
ATOM   10978 C CG  . PHE C 1 450 ? 129.617 129.612 182.704 1.00 68.00  ? 450 PHE C CG  1 
ATOM   10979 C CD1 . PHE C 1 450 ? 129.309 128.547 183.532 1.00 68.00  ? 450 PHE C CD1 1 
ATOM   10980 C CD2 . PHE C 1 450 ? 130.651 130.458 183.068 1.00 68.00  ? 450 PHE C CD2 1 
ATOM   10981 C CE1 . PHE C 1 450 ? 130.020 128.328 184.696 1.00 68.00  ? 450 PHE C CE1 1 
ATOM   10982 C CE2 . PHE C 1 450 ? 131.364 130.244 184.230 1.00 68.00  ? 450 PHE C CE2 1 
ATOM   10983 C CZ  . PHE C 1 450 ? 131.048 129.178 185.045 1.00 68.00  ? 450 PHE C CZ  1 
ATOM   10984 N N   . GLU C 1 451 ? 128.102 132.928 181.648 1.00 70.58  ? 451 GLU C N   1 
ATOM   10985 C CA  . GLU C 1 451 ? 128.362 134.220 182.271 1.00 70.58  ? 451 GLU C CA  1 
ATOM   10986 C C   . GLU C 1 451 ? 127.097 134.809 182.880 1.00 70.58  ? 451 GLU C C   1 
ATOM   10987 O O   . GLU C 1 451 ? 127.143 135.390 183.968 1.00 70.58  ? 451 GLU C O   1 
ATOM   10988 C CB  . GLU C 1 451 ? 128.972 135.184 181.255 1.00 70.58  ? 451 GLU C CB  1 
ATOM   10989 C CG  . GLU C 1 451 ? 129.575 136.431 181.879 1.00 70.58  ? 451 GLU C CG  1 
ATOM   10990 C CD  . GLU C 1 451 ? 130.746 136.120 182.794 1.00 70.58  ? 451 GLU C CD  1 
ATOM   10991 O OE1 . GLU C 1 451 ? 131.416 135.088 182.581 1.00 70.58  ? 451 GLU C OE1 1 
ATOM   10992 O OE2 . GLU C 1 451 ? 130.995 136.909 183.731 1.00 70.58  ? 451 GLU C OE2 1 
ATOM   10993 N N   . LYS C 1 452 ? 125.957 134.673 182.197 1.00 72.30  ? 452 LYS C N   1 
ATOM   10994 C CA  . LYS C 1 452 ? 124.699 135.148 182.769 1.00 72.30  ? 452 LYS C CA  1 
ATOM   10995 C C   . LYS C 1 452 ? 124.338 134.373 184.031 1.00 72.30  ? 452 LYS C C   1 
ATOM   10996 O O   . LYS C 1 452 ? 123.877 134.960 185.021 1.00 72.30  ? 452 LYS C O   1 
ATOM   10997 C CB  . LYS C 1 452 ? 123.577 135.045 181.738 1.00 72.30  ? 452 LYS C CB  1 
ATOM   10998 C CG  . LYS C 1 452 ? 122.238 135.557 182.239 1.00 72.30  ? 452 LYS C CG  1 
ATOM   10999 C CD  . LYS C 1 452 ? 121.195 135.556 181.138 1.00 72.30  ? 452 LYS C CD  1 
ATOM   11000 C CE  . LYS C 1 452 ? 120.739 134.147 180.810 1.00 72.30  ? 452 LYS C CE  1 
ATOM   11001 N NZ  . LYS C 1 452 ? 119.633 134.150 179.814 1.00 72.30  ? 452 LYS C NZ  1 
ATOM   11002 N N   . THR C 1 453 ? 124.537 133.050 184.016 1.00 74.73  ? 453 THR C N   1 
ATOM   11003 C CA  . THR C 1 453 ? 124.245 132.257 185.207 1.00 74.73  ? 453 THR C CA  1 
ATOM   11004 C C   . THR C 1 453 ? 125.124 132.680 186.379 1.00 74.73  ? 453 THR C C   1 
ATOM   11005 O O   . THR C 1 453 ? 124.650 132.777 187.517 1.00 74.73  ? 453 THR C O   1 
ATOM   11006 C CB  . THR C 1 453 ? 124.423 130.769 184.909 1.00 74.73  ? 453 THR C CB  1 
ATOM   11007 O OG1 . THR C 1 453 ? 123.536 130.386 183.851 1.00 74.73  ? 453 THR C OG1 1 
ATOM   11008 C CG2 . THR C 1 453 ? 124.109 129.939 186.145 1.00 74.73  ? 453 THR C CG2 1 
ATOM   11009 N N   . ARG C 1 454 ? 126.410 132.938 186.121 1.00 75.54  ? 454 ARG C N   1 
ATOM   11010 C CA  . ARG C 1 454 ? 127.280 133.473 187.167 1.00 75.54  ? 454 ARG C CA  1 
ATOM   11011 C C   . ARG C 1 454 ? 126.800 134.840 187.635 1.00 75.54  ? 454 ARG C C   1 
ATOM   11012 O O   . ARG C 1 454 ? 126.828 135.144 188.833 1.00 75.54  ? 454 ARG C O   1 
ATOM   11013 C CB  . ARG C 1 454 ? 128.722 133.562 186.665 1.00 75.54  ? 454 ARG C CB  1 
ATOM   11014 C CG  . ARG C 1 454 ? 129.609 134.473 187.504 1.00 75.54  ? 454 ARG C CG  1 
ATOM   11015 C CD  . ARG C 1 454 ? 131.007 134.590 186.925 1.00 75.54  ? 454 ARG C CD  1 
ATOM   11016 N NE  . ARG C 1 454 ? 131.832 133.438 187.267 1.00 75.54  ? 454 ARG C NE  1 
ATOM   11017 C CZ  . ARG C 1 454 ? 133.034 133.201 186.760 1.00 75.54  ? 454 ARG C CZ  1 
ATOM   11018 N NH1 . ARG C 1 454 ? 133.585 134.018 185.878 1.00 75.54  ? 454 ARG C NH1 1 
ATOM   11019 N NH2 . ARG C 1 454 ? 133.699 132.117 187.147 1.00 75.54  ? 454 ARG C NH2 1 
ATOM   11020 N N   . ARG C 1 455 ? 126.357 135.677 186.696 1.00 77.55  ? 455 ARG C N   1 
ATOM   11021 C CA  . ARG C 1 455 ? 125.907 137.023 187.024 1.00 77.55  ? 455 ARG C CA  1 
ATOM   11022 C C   . ARG C 1 455 ? 124.716 136.995 187.972 1.00 77.55  ? 455 ARG C C   1 
ATOM   11023 O O   . ARG C 1 455 ? 124.617 137.830 188.879 1.00 77.55  ? 455 ARG C O   1 
ATOM   11024 C CB  . ARG C 1 455 ? 125.562 137.764 185.733 1.00 77.55  ? 455 ARG C CB  1 
ATOM   11025 C CG  . ARG C 1 455 ? 124.844 139.074 185.918 1.00 77.55  ? 455 ARG C CG  1 
ATOM   11026 C CD  . ARG C 1 455 ? 124.374 139.617 184.579 1.00 77.55  ? 455 ARG C CD  1 
ATOM   11027 N NE  . ARG C 1 455 ? 125.486 140.012 183.724 1.00 77.55  ? 455 ARG C NE  1 
ATOM   11028 C CZ  . ARG C 1 455 ? 125.662 139.585 182.481 1.00 77.55  ? 455 ARG C CZ  1 
ATOM   11029 N NH1 . ARG C 1 455 ? 124.806 138.757 181.906 1.00 77.55  ? 455 ARG C NH1 1 
ATOM   11030 N NH2 . ARG C 1 455 ? 126.723 140.003 181.796 1.00 77.55  ? 455 ARG C NH2 1 
ATOM   11031 N N   . GLN C 1 456 ? 123.796 136.047 187.773 1.00 81.62  ? 456 GLN C N   1 
ATOM   11032 C CA  . GLN C 1 456 ? 122.660 135.924 188.684 1.00 81.62  ? 456 GLN C CA  1 
ATOM   11033 C C   . GLN C 1 456 ? 123.122 135.631 190.108 1.00 81.62  ? 456 GLN C C   1 
ATOM   11034 O O   . GLN C 1 456 ? 122.698 136.295 191.061 1.00 81.62  ? 456 GLN C O   1 
ATOM   11035 C CB  . GLN C 1 456 ? 121.708 134.834 188.196 1.00 81.62  ? 456 GLN C CB  1 
ATOM   11036 C CG  . GLN C 1 456 ? 120.784 135.267 187.075 1.00 81.62  ? 456 GLN C CG  1 
ATOM   11037 C CD  . GLN C 1 456 ? 119.613 134.327 186.902 1.00 81.62  ? 456 GLN C CD  1 
ATOM   11038 O OE1 . GLN C 1 456 ? 119.391 133.785 185.820 1.00 81.62  ? 456 GLN C OE1 1 
ATOM   11039 N NE2 . GLN C 1 456 ? 118.853 134.126 187.972 1.00 81.62  ? 456 GLN C NE2 1 
ATOM   11040 N N   . LEU C 1 457 ? 123.990 134.636 190.272 1.00 85.57  ? 457 LEU C N   1 
ATOM   11041 C CA  . LEU C 1 457 ? 124.518 134.265 191.584 1.00 85.57  ? 457 LEU C CA  1 
ATOM   11042 C C   . LEU C 1 457 ? 125.621 135.248 191.954 1.00 85.57  ? 457 LEU C C   1 
ATOM   11043 O O   . LEU C 1 457 ? 126.785 135.060 191.593 1.00 85.57  ? 457 LEU C O   1 
ATOM   11044 C CB  . LEU C 1 457 ? 125.039 132.833 191.563 1.00 85.57  ? 457 LEU C CB  1 
ATOM   11045 C CG  . LEU C 1 457 ? 124.021 131.733 191.263 1.00 85.57  ? 457 LEU C CG  1 
ATOM   11046 C CD1 . LEU C 1 457 ? 124.718 130.400 191.058 1.00 85.57  ? 457 LEU C CD1 1 
ATOM   11047 C CD2 . LEU C 1 457 ? 122.997 131.634 192.377 1.00 85.57  ? 457 LEU C CD2 1 
ATOM   11048 N N   . ARG C 1 458 ? 125.261 136.303 192.688 1.00 89.20  ? 458 ARG C N   1 
ATOM   11049 C CA  . ARG C 1 458 ? 126.222 137.363 192.979 1.00 89.20  ? 458 ARG C CA  1 
ATOM   11050 C C   . ARG C 1 458 ? 127.290 136.892 193.961 1.00 89.20  ? 458 ARG C C   1 
ATOM   11051 O O   . ARG C 1 458 ? 128.482 136.870 193.636 1.00 89.20  ? 458 ARG C O   1 
ATOM   11052 C CB  . ARG C 1 458 ? 125.497 138.598 193.516 1.00 89.20  ? 458 ARG C CB  1 
ATOM   11053 C CG  . ARG C 1 458 ? 124.595 139.271 192.497 1.00 89.20  ? 458 ARG C CG  1 
ATOM   11054 C CD  . ARG C 1 458 ? 123.883 140.476 193.087 1.00 89.20  ? 458 ARG C CD  1 
ATOM   11055 N NE  . ARG C 1 458 ? 124.812 141.549 193.422 1.00 89.20  ? 458 ARG C NE  1 
ATOM   11056 C CZ  . ARG C 1 458 ? 124.481 142.645 194.092 1.00 89.20  ? 458 ARG C CZ  1 
ATOM   11057 N NH1 . ARG C 1 458 ? 123.241 142.857 194.502 1.00 89.20  ? 458 ARG C NH1 1 
ATOM   11058 N NH2 . ARG C 1 458 ? 125.416 143.553 194.353 1.00 89.20  ? 458 ARG C NH2 1 
ATOM   11059 N N   . GLU C 1 459 ? 126.882 136.507 195.170 1.00 92.34  ? 459 GLU C N   1 
ATOM   11060 C CA  . GLU C 1 459 ? 127.836 136.140 196.206 1.00 92.34  ? 459 GLU C CA  1 
ATOM   11061 C C   . GLU C 1 459 ? 127.521 134.818 196.892 1.00 92.34  ? 459 GLU C C   1 
ATOM   11062 O O   . GLU C 1 459 ? 128.356 134.327 197.661 1.00 92.34  ? 459 GLU C O   1 
ATOM   11063 C CB  . GLU C 1 459 ? 127.921 137.251 197.266 1.00 92.34  ? 459 GLU C CB  1 
ATOM   11064 C CG  . GLU C 1 459 ? 129.240 137.295 198.018 1.00 92.34  ? 459 GLU C CG  1 
ATOM   11065 C CD  . GLU C 1 459 ? 130.398 137.707 197.131 1.00 92.34  ? 459 GLU C CD  1 
ATOM   11066 O OE1 . GLU C 1 459 ? 130.232 138.661 196.342 1.00 92.34  ? 459 GLU C OE1 1 
ATOM   11067 O OE2 . GLU C 1 459 ? 131.472 137.076 197.220 1.00 92.34  ? 459 GLU C OE2 1 
ATOM   11068 N N   . ASN C 1 460 ? 126.358 134.223 196.638 1.00 92.88  ? 460 ASN C N   1 
ATOM   11069 C CA  . ASN C 1 460 ? 125.981 132.982 197.299 1.00 92.88  ? 460 ASN C CA  1 
ATOM   11070 C C   . ASN C 1 460 ? 126.650 131.753 196.701 1.00 92.88  ? 460 ASN C C   1 
ATOM   11071 O O   . ASN C 1 460 ? 126.558 130.670 197.288 1.00 92.88  ? 460 ASN C O   1 
ATOM   11072 C CB  . ASN C 1 460 ? 124.461 132.803 197.257 1.00 92.88  ? 460 ASN C CB  1 
ATOM   11073 C CG  . ASN C 1 460 ? 123.718 134.082 197.569 1.00 92.88  ? 460 ASN C CG  1 
ATOM   11074 O OD1 . ASN C 1 460 ? 122.835 134.495 196.822 1.00 92.88  ? 460 ASN C OD1 1 
ATOM   11075 N ND2 . ASN C 1 460 ? 124.077 134.722 198.674 1.00 92.88  ? 460 ASN C ND2 1 
ATOM   11076 N N   . ALA C 1 461 ? 127.317 131.890 195.558 1.00 91.32  ? 461 ALA C N   1 
ATOM   11077 C CA  . ALA C 1 461 ? 127.993 130.772 194.920 1.00 91.32  ? 461 ALA C CA  1 
ATOM   11078 C C   . ALA C 1 461 ? 129.298 131.256 194.311 1.00 91.32  ? 461 ALA C C   1 
ATOM   11079 O O   . ALA C 1 461 ? 129.482 132.447 194.050 1.00 91.32  ? 461 ALA C O   1 
ATOM   11080 C CB  . ALA C 1 461 ? 127.117 130.119 193.844 1.00 91.32  ? 461 ALA C CB  1 
ATOM   11081 N N   . GLU C 1 462 ? 130.209 130.311 194.086 1.00 89.08  ? 462 GLU C N   1 
ATOM   11082 C CA  . GLU C 1 462 ? 131.476 130.595 193.430 1.00 89.08  ? 462 GLU C CA  1 
ATOM   11083 C C   . GLU C 1 462 ? 131.840 129.433 192.517 1.00 89.08  ? 462 GLU C C   1 
ATOM   11084 O O   . GLU C 1 462 ? 131.469 128.286 192.780 1.00 89.08  ? 462 GLU C O   1 
ATOM   11085 C CB  . GLU C 1 462 ? 132.587 130.860 194.457 1.00 89.08  ? 462 GLU C CB  1 
ATOM   11086 C CG  . GLU C 1 462 ? 133.241 129.616 195.021 1.00 89.08  ? 462 GLU C CG  1 
ATOM   11087 C CD  . GLU C 1 462 ? 133.983 129.881 196.317 1.00 89.08  ? 462 GLU C CD  1 
ATOM   11088 O OE1 . GLU C 1 462 ? 135.035 130.551 196.278 1.00 89.08  ? 462 GLU C OE1 1 
ATOM   11089 O OE2 . GLU C 1 462 ? 133.518 129.414 197.377 1.00 89.08  ? 462 GLU C OE2 1 
ATOM   11090 N N   . ASP C 1 463 ? 132.560 129.743 191.441 1.00 83.70  ? 463 ASP C N   1 
ATOM   11091 C CA  . ASP C 1 463 ? 132.862 128.756 190.412 1.00 83.70  ? 463 ASP C CA  1 
ATOM   11092 C C   . ASP C 1 463 ? 133.829 127.696 190.930 1.00 83.70  ? 463 ASP C C   1 
ATOM   11093 O O   . ASP C 1 463 ? 134.781 128.000 191.654 1.00 83.70  ? 463 ASP C O   1 
ATOM   11094 C CB  . ASP C 1 463 ? 133.445 129.457 189.185 1.00 83.70  ? 463 ASP C CB  1 
ATOM   11095 C CG  . ASP C 1 463 ? 134.020 128.489 188.174 1.00 83.70  ? 463 ASP C CG  1 
ATOM   11096 O OD1 . ASP C 1 463 ? 133.263 128.016 187.300 1.00 83.70  ? 463 ASP C OD1 1 
ATOM   11097 O OD2 . ASP C 1 463 ? 135.233 128.209 188.247 1.00 83.70  ? 463 ASP C OD2 1 
ATOM   11098 N N   . MET C 1 464 ? 133.581 126.440 190.548 1.00 82.13  ? 464 MET C N   1 
ATOM   11099 C CA  . MET C 1 464 ? 134.413 125.328 190.989 1.00 82.13  ? 464 MET C CA  1 
ATOM   11100 C C   . MET C 1 464 ? 135.523 124.966 190.009 1.00 82.13  ? 464 MET C C   1 
ATOM   11101 O O   . MET C 1 464 ? 136.302 124.051 190.296 1.00 82.13  ? 464 MET C O   1 
ATOM   11102 C CB  . MET C 1 464 ? 133.555 124.084 191.246 1.00 82.13  ? 464 MET C CB  1 
ATOM   11103 C CG  . MET C 1 464 ? 132.351 124.314 192.137 1.00 82.13  ? 464 MET C CG  1 
ATOM   11104 S SD  . MET C 1 464 ? 131.434 122.785 192.413 1.00 82.13  ? 464 MET C SD  1 
ATOM   11105 C CE  . MET C 1 464 ? 131.555 122.022 190.799 1.00 82.13  ? 464 MET C CE  1 
ATOM   11106 N N   . GLY C 1 465 ? 135.626 125.651 188.872 1.00 80.02  ? 465 GLY C N   1 
ATOM   11107 C CA  . GLY C 1 465 ? 136.733 125.446 187.959 1.00 80.02  ? 465 GLY C CA  1 
ATOM   11108 C C   . GLY C 1 465 ? 136.438 124.626 186.722 1.00 80.02  ? 465 GLY C C   1 
ATOM   11109 O O   . GLY C 1 465 ? 137.259 124.620 185.795 1.00 80.02  ? 465 GLY C O   1 
ATOM   11110 N N   . ASN C 1 466 ? 135.302 123.941 186.664 1.00 75.23  ? 466 ASN C N   1 
ATOM   11111 C CA  . ASN C 1 466 ? 134.946 123.105 185.525 1.00 75.23  ? 466 ASN C CA  1 
ATOM   11112 C C   . ASN C 1 466 ? 133.628 123.552 184.904 1.00 75.23  ? 466 ASN C C   1 
ATOM   11113 O O   . ASN C 1 466 ? 132.812 122.737 184.480 1.00 75.23  ? 466 ASN C O   1 
ATOM   11114 C CB  . ASN C 1 466 ? 134.890 121.633 185.928 1.00 75.23  ? 466 ASN C CB  1 
ATOM   11115 C CG  . ASN C 1 466 ? 134.011 121.383 187.144 1.00 75.23  ? 466 ASN C CG  1 
ATOM   11116 O OD1 . ASN C 1 466 ? 133.163 122.199 187.498 1.00 75.23  ? 466 ASN C OD1 1 
ATOM   11117 N ND2 . ASN C 1 466 ? 134.220 120.243 187.792 1.00 75.23  ? 466 ASN C ND2 1 
ATOM   11118 N N   . GLY C 1 467 ? 133.407 124.861 184.841 1.00 73.37  ? 467 GLY C N   1 
ATOM   11119 C CA  . GLY C 1 467 ? 132.171 125.368 184.277 1.00 73.37  ? 467 GLY C CA  1 
ATOM   11120 C C   . GLY C 1 467 ? 130.948 125.087 185.113 1.00 73.37  ? 467 GLY C C   1 
ATOM   11121 O O   . GLY C 1 467 ? 129.834 125.066 184.584 1.00 73.37  ? 467 GLY C O   1 
ATOM   11122 N N   . CYS C 1 468 ? 131.128 124.870 186.412 1.00 76.84  ? 468 CYS C N   1 
ATOM   11123 C CA  . CYS C 1 468 ? 130.045 124.474 187.294 1.00 76.84  ? 468 CYS C CA  1 
ATOM   11124 C C   . CYS C 1 468 ? 130.155 125.262 188.591 1.00 76.84  ? 468 CYS C C   1 
ATOM   11125 O O   . CYS C 1 468 ? 131.232 125.730 188.966 1.00 76.84  ? 468 CYS C O   1 
ATOM   11126 C CB  . CYS C 1 468 ? 130.082 122.966 187.562 1.00 76.84  ? 468 CYS C CB  1 
ATOM   11127 S SG  . CYS C 1 468 ? 128.745 122.348 188.580 1.00 76.84  ? 468 CYS C SG  1 
ATOM   11128 N N   . PHE C 1 469 ? 129.025 125.409 189.275 1.00 77.45  ? 469 PHE C N   1 
ATOM   11129 C CA  . PHE C 1 469 ? 128.934 126.263 190.449 1.00 77.45  ? 469 PHE C CA  1 
ATOM   11130 C C   . PHE C 1 469 ? 128.731 125.431 191.707 1.00 77.45  ? 469 PHE C C   1 
ATOM   11131 O O   . PHE C 1 469 ? 128.166 124.335 191.674 1.00 77.45  ? 469 PHE C O   1 
ATOM   11132 C CB  . PHE C 1 469 ? 127.782 127.263 190.310 1.00 77.45  ? 469 PHE C CB  1 
ATOM   11133 C CG  . PHE C 1 469 ? 127.998 128.287 189.243 1.00 77.45  ? 469 PHE C CG  1 
ATOM   11134 C CD1 . PHE C 1 469 ? 128.865 129.346 189.442 1.00 77.45  ? 469 PHE C CD1 1 
ATOM   11135 C CD2 . PHE C 1 469 ? 127.335 128.188 188.033 1.00 77.45  ? 469 PHE C CD2 1 
ATOM   11136 C CE1 . PHE C 1 469 ? 129.066 130.285 188.455 1.00 77.45  ? 469 PHE C CE1 1 
ATOM   11137 C CE2 . PHE C 1 469 ? 127.530 129.125 187.043 1.00 77.45  ? 469 PHE C CE2 1 
ATOM   11138 C CZ  . PHE C 1 469 ? 128.397 130.172 187.254 1.00 77.45  ? 469 PHE C CZ  1 
ATOM   11139 N N   . LYS C 1 470 ? 129.203 125.976 192.825 1.00 86.00  ? 470 LYS C N   1 
ATOM   11140 C CA  . LYS C 1 470 ? 128.957 125.416 194.148 1.00 86.00  ? 470 LYS C CA  1 
ATOM   11141 C C   . LYS C 1 470 ? 128.182 126.442 194.955 1.00 86.00  ? 470 LYS C C   1 
ATOM   11142 O O   . LYS C 1 470 ? 128.654 127.566 195.154 1.00 86.00  ? 470 LYS C O   1 
ATOM   11143 C CB  . LYS C 1 470 ? 130.258 125.052 194.862 1.00 86.00  ? 470 LYS C CB  1 
ATOM   11144 C CG  . LYS C 1 470 ? 130.111 124.923 196.366 1.00 86.00  ? 470 LYS C CG  1 
ATOM   11145 C CD  . LYS C 1 470 ? 131.059 123.880 196.924 1.00 86.00  ? 470 LYS C CD  1 
ATOM   11146 C CE  . LYS C 1 470 ? 131.096 123.927 198.444 1.00 86.00  ? 470 LYS C CE  1 
ATOM   11147 N NZ  . LYS C 1 470 ? 129.983 123.150 199.056 1.00 86.00  ? 470 LYS C NZ  1 
ATOM   11148 N N   . ILE C 1 471 ? 126.999 126.056 195.413 1.00 88.43  ? 471 ILE C N   1 
ATOM   11149 C CA  . ILE C 1 471 ? 126.115 126.933 196.167 1.00 88.43  ? 471 ILE C CA  1 
ATOM   11150 C C   . ILE C 1 471 ? 126.258 126.594 197.642 1.00 88.43  ? 471 ILE C C   1 
ATOM   11151 O O   . ILE C 1 471 ? 126.221 125.418 198.021 1.00 88.43  ? 471 ILE C O   1 
ATOM   11152 C CB  . ILE C 1 471 ? 124.659 126.782 195.696 1.00 88.43  ? 471 ILE C CB  1 
ATOM   11153 C CG1 . ILE C 1 471 ? 124.527 127.199 194.231 1.00 88.43  ? 471 ILE C CG1 1 
ATOM   11154 C CG2 . ILE C 1 471 ? 123.739 127.606 196.553 1.00 88.43  ? 471 ILE C CG2 1 
ATOM   11155 C CD1 . ILE C 1 471 ? 123.578 126.332 193.437 1.00 88.43  ? 471 ILE C CD1 1 
ATOM   11156 N N   . TYR C 1 472 ? 126.444 127.617 198.473 1.00 92.14  ? 472 TYR C N   1 
ATOM   11157 C CA  . TYR C 1 472 ? 126.665 127.425 199.901 1.00 92.14  ? 472 TYR C CA  1 
ATOM   11158 C C   . TYR C 1 472 ? 125.397 127.548 200.737 1.00 92.14  ? 472 TYR C C   1 
ATOM   11159 O O   . TYR C 1 472 ? 125.474 127.451 201.965 1.00 92.14  ? 472 TYR C O   1 
ATOM   11160 C CB  . TYR C 1 472 ? 127.718 128.417 200.404 1.00 92.14  ? 472 TYR C CB  1 
ATOM   11161 C CG  . TYR C 1 472 ? 129.124 128.062 199.978 1.00 92.14  ? 472 TYR C CG  1 
ATOM   11162 C CD1 . TYR C 1 472 ? 129.628 128.477 198.754 1.00 92.14  ? 472 TYR C CD1 1 
ATOM   11163 C CD2 . TYR C 1 472 ? 129.947 127.310 200.805 1.00 92.14  ? 472 TYR C CD2 1 
ATOM   11164 C CE1 . TYR C 1 472 ? 130.912 128.149 198.365 1.00 92.14  ? 472 TYR C CE1 1 
ATOM   11165 C CE2 . TYR C 1 472 ? 131.231 126.980 200.426 1.00 92.14  ? 472 TYR C CE2 1 
ATOM   11166 C CZ  . TYR C 1 472 ? 131.710 127.402 199.206 1.00 92.14  ? 472 TYR C CZ  1 
ATOM   11167 O OH  . TYR C 1 472 ? 132.991 127.071 198.829 1.00 92.14  ? 472 TYR C OH  1 
ATOM   11168 N N   . HIS C 1 473 ? 124.243 127.752 200.114 1.00 92.39  ? 473 HIS C N   1 
ATOM   11169 C CA  . HIS C 1 473 ? 122.962 127.760 200.804 1.00 92.39  ? 473 HIS C CA  1 
ATOM   11170 C C   . HIS C 1 473 ? 122.095 126.616 200.293 1.00 92.39  ? 473 HIS C C   1 
ATOM   11171 O O   . HIS C 1 473 ? 122.257 126.133 199.171 1.00 92.39  ? 473 HIS C O   1 
ATOM   11172 C CB  . HIS C 1 473 ? 122.248 129.106 200.622 1.00 92.39  ? 473 HIS C CB  1 
ATOM   11173 C CG  . HIS C 1 473 ? 121.816 129.373 199.215 1.00 92.39  ? 473 HIS C CG  1 
ATOM   11174 N ND1 . HIS C 1 473 ? 120.639 128.884 198.692 1.00 92.39  ? 473 HIS C ND1 1 
ATOM   11175 C CD2 . HIS C 1 473 ? 122.390 130.104 198.230 1.00 92.39  ? 473 HIS C CD2 1 
ATOM   11176 C CE1 . HIS C 1 473 ? 120.516 129.284 197.438 1.00 92.39  ? 473 HIS C CE1 1 
ATOM   11177 N NE2 . HIS C 1 473 ? 121.569 130.020 197.131 1.00 92.39  ? 473 HIS C NE2 1 
ATOM   11178 N N   . LYS C 1 474 ? 121.166 126.182 201.141 1.00 94.37  ? 474 LYS C N   1 
ATOM   11179 C CA  . LYS C 1 474 ? 120.287 125.064 200.815 1.00 94.37  ? 474 LYS C CA  1 
ATOM   11180 C C   . LYS C 1 474 ? 119.352 125.491 199.689 1.00 94.37  ? 474 LYS C C   1 
ATOM   11181 O O   . LYS C 1 474 ? 118.394 126.237 199.917 1.00 94.37  ? 474 LYS C O   1 
ATOM   11182 C CB  . LYS C 1 474 ? 119.507 124.629 202.052 1.00 94.37  ? 474 LYS C CB  1 
ATOM   11183 C CG  . LYS C 1 474 ? 118.810 123.291 201.916 1.00 94.37  ? 474 LYS C CG  1 
ATOM   11184 C CD  . LYS C 1 474 ? 118.059 122.934 203.186 1.00 94.37  ? 474 LYS C CD  1 
ATOM   11185 C CE  . LYS C 1 474 ? 119.025 122.680 204.330 1.00 94.37  ? 474 LYS C CE  1 
ATOM   11186 N NZ  . LYS C 1 474 ? 119.856 121.469 204.095 1.00 94.37  ? 474 LYS C NZ  1 
ATOM   11187 N N   . CYS C 1 475 ? 119.630 125.026 198.474 1.00 95.22  ? 475 CYS C N   1 
ATOM   11188 C CA  . CYS C 1 475 ? 118.892 125.432 197.282 1.00 95.22  ? 475 CYS C CA  1 
ATOM   11189 C C   . CYS C 1 475 ? 118.106 124.224 196.782 1.00 95.22  ? 475 CYS C C   1 
ATOM   11190 O O   . CYS C 1 475 ? 118.680 123.308 196.184 1.00 95.22  ? 475 CYS C O   1 
ATOM   11191 C CB  . CYS C 1 475 ? 119.849 125.969 196.218 1.00 95.22  ? 475 CYS C CB  1 
ATOM   11192 S SG  . CYS C 1 475 ? 119.090 126.728 194.758 1.00 95.22  ? 475 CYS C SG  1 
ATOM   11193 N N   . ASP C 1 476 ? 116.796 124.227 197.028 1.00 94.89  ? 476 ASP C N   1 
ATOM   11194 C CA  . ASP C 1 476 ? 115.938 123.092 196.719 1.00 94.89  ? 476 ASP C CA  1 
ATOM   11195 C C   . ASP C 1 476 ? 115.472 123.164 195.264 1.00 94.89  ? 476 ASP C C   1 
ATOM   11196 O O   . ASP C 1 476 ? 115.967 123.964 194.466 1.00 94.89  ? 476 ASP C O   1 
ATOM   11197 C CB  . ASP C 1 476 ? 114.761 123.037 197.692 1.00 94.89  ? 476 ASP C CB  1 
ATOM   11198 C CG  . ASP C 1 476 ? 113.884 124.273 197.623 1.00 94.89  ? 476 ASP C CG  1 
ATOM   11199 O OD1 . ASP C 1 476 ? 114.388 125.381 197.904 1.00 94.89  ? 476 ASP C OD1 1 
ATOM   11200 O OD2 . ASP C 1 476 ? 112.688 124.138 197.287 1.00 94.89  ? 476 ASP C OD2 1 
ATOM   11201 N N   . ASN C 1 477 ? 114.510 122.308 194.905 1.00 94.39  ? 477 ASN C N   1 
ATOM   11202 C CA  . ASN C 1 477 ? 114.032 122.259 193.525 1.00 94.39  ? 477 ASN C CA  1 
ATOM   11203 C C   . ASN C 1 477 ? 113.350 123.561 193.124 1.00 94.39  ? 477 ASN C C   1 
ATOM   11204 O O   . ASN C 1 477 ? 113.515 124.030 191.992 1.00 94.39  ? 477 ASN C O   1 
ATOM   11205 C CB  . ASN C 1 477 ? 113.084 121.076 193.336 1.00 94.39  ? 477 ASN C CB  1 
ATOM   11206 C CG  . ASN C 1 477 ? 113.807 119.744 193.351 1.00 94.39  ? 477 ASN C CG  1 
ATOM   11207 O OD1 . ASN C 1 477 ? 115.033 119.688 193.260 1.00 94.39  ? 477 ASN C OD1 1 
ATOM   11208 N ND2 . ASN C 1 477 ? 113.047 118.661 193.460 1.00 94.39  ? 477 ASN C ND2 1 
ATOM   11209 N N   . ALA C 1 478 ? 112.568 124.152 194.029 1.00 93.86  ? 478 ALA C N   1 
ATOM   11210 C CA  . ALA C 1 478 ? 111.995 125.465 193.750 1.00 93.86  ? 478 ALA C CA  1 
ATOM   11211 C C   . ALA C 1 478 ? 113.090 126.510 193.590 1.00 93.86  ? 478 ALA C C   1 
ATOM   11212 O O   . ALA C 1 478 ? 113.022 127.363 192.699 1.00 93.86  ? 478 ALA C O   1 
ATOM   11213 C CB  . ALA C 1 478 ? 111.023 125.863 194.860 1.00 93.86  ? 478 ALA C CB  1 
ATOM   11214 N N   . CYS C 1 479 ? 114.116 126.447 194.441 1.00 92.78  ? 479 CYS C N   1 
ATOM   11215 C CA  . CYS C 1 479 ? 115.271 127.331 194.311 1.00 92.78  ? 479 CYS C CA  1 
ATOM   11216 C C   . CYS C 1 479 ? 115.983 127.143 192.974 1.00 92.78  ? 479 CYS C C   1 
ATOM   11217 O O   . CYS C 1 479 ? 116.335 128.124 192.305 1.00 92.78  ? 479 CYS C O   1 
ATOM   11218 C CB  . CYS C 1 479 ? 116.227 127.075 195.474 1.00 92.78  ? 479 CYS C CB  1 
ATOM   11219 S SG  . CYS C 1 479 ? 117.730 128.050 195.486 1.00 92.78  ? 479 CYS C SG  1 
ATOM   11220 N N   . ILE C 1 480 ? 116.206 125.891 192.570 1.00 89.81  ? 480 ILE C N   1 
ATOM   11221 C CA  . ILE C 1 480 ? 116.900 125.628 191.312 1.00 89.81  ? 480 ILE C CA  1 
ATOM   11222 C C   . ILE C 1 480 ? 116.074 126.126 190.133 1.00 89.81  ? 480 ILE C C   1 
ATOM   11223 O O   . ILE C 1 480 ? 116.607 126.717 189.185 1.00 89.81  ? 480 ILE C O   1 
ATOM   11224 C CB  . ILE C 1 480 ? 117.228 124.129 191.186 1.00 89.81  ? 480 ILE C CB  1 
ATOM   11225 C CG1 . ILE C 1 480 ? 118.305 123.736 192.200 1.00 89.81  ? 480 ILE C CG1 1 
ATOM   11226 C CG2 . ILE C 1 480 ? 117.679 123.792 189.774 1.00 89.81  ? 480 ILE C CG2 1 
ATOM   11227 C CD1 . ILE C 1 480 ? 119.668 124.321 191.905 1.00 89.81  ? 480 ILE C CD1 1 
ATOM   11228 N N   . GLU C 1 481 ? 114.760 125.894 190.170 1.00 90.02  ? 481 GLU C N   1 
ATOM   11229 C CA  . GLU C 1 481 ? 113.893 126.369 189.098 1.00 90.02  ? 481 GLU C CA  1 
ATOM   11230 C C   . GLU C 1 481 ? 113.851 127.892 189.055 1.00 90.02  ? 481 GLU C C   1 
ATOM   11231 O O   . GLU C 1 481 ? 113.763 128.486 187.975 1.00 90.02  ? 481 GLU C O   1 
ATOM   11232 C CB  . GLU C 1 481 ? 112.488 125.794 189.268 1.00 90.02  ? 481 GLU C CB  1 
ATOM   11233 C CG  . GLU C 1 481 ? 111.536 126.137 188.136 1.00 90.02  ? 481 GLU C CG  1 
ATOM   11234 C CD  . GLU C 1 481 ? 110.116 126.346 188.618 1.00 90.02  ? 481 GLU C CD  1 
ATOM   11235 O OE1 . GLU C 1 481 ? 109.721 125.689 189.604 1.00 90.02  ? 481 GLU C OE1 1 
ATOM   11236 O OE2 . GLU C 1 481 ? 109.395 127.167 188.013 1.00 90.02  ? 481 GLU C OE2 1 
ATOM   11237 N N   . SER C 1 482 ? 113.900 128.541 190.221 1.00 90.70  ? 482 SER C N   1 
ATOM   11238 C CA  . SER C 1 482 ? 113.963 129.999 190.253 1.00 90.70  ? 482 SER C CA  1 
ATOM   11239 C C   . SER C 1 482 ? 115.260 130.505 189.636 1.00 90.70  ? 482 SER C C   1 
ATOM   11240 O O   . SER C 1 482 ? 115.266 131.520 188.931 1.00 90.70  ? 482 SER C O   1 
ATOM   11241 C CB  . SER C 1 482 ? 113.821 130.498 191.690 1.00 90.70  ? 482 SER C CB  1 
ATOM   11242 O OG  . SER C 1 482 ? 115.043 130.372 192.396 1.00 90.70  ? 482 SER C OG  1 
ATOM   11243 N N   . ILE C 1 483 ? 116.371 129.815 189.903 1.00 88.16  ? 483 ILE C N   1 
ATOM   11244 C CA  . ILE C 1 483 ? 117.638 130.181 189.273 1.00 88.16  ? 483 ILE C CA  1 
ATOM   11245 C C   . ILE C 1 483 ? 117.544 130.021 187.761 1.00 88.16  ? 483 ILE C C   1 
ATOM   11246 O O   . ILE C 1 483 ? 117.982 130.892 186.998 1.00 88.16  ? 483 ILE C O   1 
ATOM   11247 C CB  . ILE C 1 483 ? 118.792 129.345 189.857 1.00 88.16  ? 483 ILE C CB  1 
ATOM   11248 C CG1 . ILE C 1 483 ? 119.186 129.866 191.238 1.00 88.16  ? 483 ILE C CG1 1 
ATOM   11249 C CG2 . ILE C 1 483 ? 119.994 129.367 188.927 1.00 88.16  ? 483 ILE C CG2 1 
ATOM   11250 C CD1 . ILE C 1 483 ? 120.034 128.899 192.033 1.00 88.16  ? 483 ILE C CD1 1 
ATOM   11251 N N   . ARG C 1 484 ? 116.967 128.908 187.305 1.00 84.61  ? 484 ARG C N   1 
ATOM   11252 C CA  . ARG C 1 484 ? 116.859 128.650 185.871 1.00 84.61  ? 484 ARG C CA  1 
ATOM   11253 C C   . ARG C 1 484 ? 115.954 129.667 185.185 1.00 84.61  ? 484 ARG C C   1 
ATOM   11254 O O   . ARG C 1 484 ? 116.222 130.076 184.049 1.00 84.61  ? 484 ARG C O   1 
ATOM   11255 C CB  . ARG C 1 484 ? 116.344 127.232 185.633 1.00 84.61  ? 484 ARG C CB  1 
ATOM   11256 C CG  . ARG C 1 484 ? 117.301 126.139 186.074 1.00 84.61  ? 484 ARG C CG  1 
ATOM   11257 C CD  . ARG C 1 484 ? 116.945 124.812 185.431 1.00 84.61  ? 484 ARG C CD  1 
ATOM   11258 N NE  . ARG C 1 484 ? 115.681 124.288 185.935 1.00 84.61  ? 484 ARG C NE  1 
ATOM   11259 C CZ  . ARG C 1 484 ? 115.549 123.131 186.569 1.00 84.61  ? 484 ARG C CZ  1 
ATOM   11260 N NH1 . ARG C 1 484 ? 116.588 122.342 186.791 1.00 84.61  ? 484 ARG C NH1 1 
ATOM   11261 N NH2 . ARG C 1 484 ? 114.346 122.756 186.991 1.00 84.61  ? 484 ARG C NH2 1 
ATOM   11262 N N   . ASN C 1 485 ? 114.875 130.080 185.853 1.00 89.27  ? 485 ASN C N   1 
ATOM   11263 C CA  . ASN C 1 485 ? 113.936 131.018 185.247 1.00 89.27  ? 485 ASN C CA  1 
ATOM   11264 C C   . ASN C 1 485 ? 114.512 132.425 185.163 1.00 89.27  ? 485 ASN C C   1 
ATOM   11265 O O   . ASN C 1 485 ? 114.057 133.230 184.342 1.00 89.27  ? 485 ASN C O   1 
ATOM   11266 C CB  . ASN C 1 485 ? 112.627 131.034 186.035 1.00 89.27  ? 485 ASN C CB  1 
ATOM   11267 C CG  . ASN C 1 485 ? 111.784 129.797 185.793 1.00 89.27  ? 485 ASN C CG  1 
ATOM   11268 O OD1 . ASN C 1 485 ? 112.247 128.822 185.203 1.00 89.27  ? 485 ASN C OD1 1 
ATOM   11269 N ND2 . ASN C 1 485 ? 110.538 129.833 186.250 1.00 89.27  ? 485 ASN C ND2 1 
ATOM   11270 N N   . GLY C 1 486 ? 115.499 132.742 185.994 1.00 90.22  ? 486 GLY C N   1 
ATOM   11271 C CA  . GLY C 1 486 ? 116.076 134.067 186.028 1.00 90.22  ? 486 GLY C CA  1 
ATOM   11272 C C   . GLY C 1 486 ? 115.494 135.003 187.062 1.00 90.22  ? 486 GLY C C   1 
ATOM   11273 O O   . GLY C 1 486 ? 115.774 136.205 187.008 1.00 90.22  ? 486 GLY C O   1 
ATOM   11274 N N   . THR C 1 487 ? 114.693 134.494 187.999 1.00 92.58  ? 487 THR C N   1 
ATOM   11275 C CA  . THR C 1 487 ? 114.076 135.303 189.043 1.00 92.58  ? 487 THR C CA  1 
ATOM   11276 C C   . THR C 1 487 ? 114.656 135.007 190.423 1.00 92.58  ? 487 THR C C   1 
ATOM   11277 O O   . THR C 1 487 ? 113.970 135.180 191.437 1.00 92.58  ? 487 THR C O   1 
ATOM   11278 C CB  . THR C 1 487 ? 112.561 135.095 189.045 1.00 92.58  ? 487 THR C CB  1 
ATOM   11279 O OG1 . THR C 1 487 ? 111.977 135.818 190.136 1.00 92.58  ? 487 THR C OG1 1 
ATOM   11280 C CG2 . THR C 1 487 ? 112.223 133.616 189.176 1.00 92.58  ? 487 THR C CG2 1 
ATOM   11281 N N   . TYR C 1 488 ? 115.909 134.565 190.479 1.00 90.53  ? 488 TYR C N   1 
ATOM   11282 C CA  . TYR C 1 488 ? 116.539 134.229 191.749 1.00 90.53  ? 488 TYR C CA  1 
ATOM   11283 C C   . TYR C 1 488 ? 116.828 135.494 192.550 1.00 90.53  ? 488 TYR C C   1 
ATOM   11284 O O   . TYR C 1 488 ? 117.328 136.484 192.008 1.00 90.53  ? 488 TYR C O   1 
ATOM   11285 C CB  . TYR C 1 488 ? 117.825 133.444 191.499 1.00 90.53  ? 488 TYR C CB  1 
ATOM   11286 C CG  . TYR C 1 488 ? 118.651 133.168 192.734 1.00 90.53  ? 488 TYR C CG  1 
ATOM   11287 C CD1 . TYR C 1 488 ? 118.271 132.192 193.645 1.00 90.53  ? 488 TYR C CD1 1 
ATOM   11288 C CD2 . TYR C 1 488 ? 119.824 133.869 192.978 1.00 90.53  ? 488 TYR C CD2 1 
ATOM   11289 C CE1 . TYR C 1 488 ? 119.028 131.931 194.770 1.00 90.53  ? 488 TYR C CE1 1 
ATOM   11290 C CE2 . TYR C 1 488 ? 120.586 133.616 194.101 1.00 90.53  ? 488 TYR C CE2 1 
ATOM   11291 C CZ  . TYR C 1 488 ? 120.185 132.646 194.992 1.00 90.53  ? 488 TYR C CZ  1 
ATOM   11292 O OH  . TYR C 1 488 ? 120.944 132.392 196.110 1.00 90.53  ? 488 TYR C OH  1 
ATOM   11293 N N   . ASP C 1 489 ? 116.510 135.458 193.842 1.00 95.85  ? 489 ASP C N   1 
ATOM   11294 C CA  . ASP C 1 489 ? 116.718 136.585 194.747 1.00 95.85  ? 489 ASP C CA  1 
ATOM   11295 C C   . ASP C 1 489 ? 117.817 136.212 195.736 1.00 95.85  ? 489 ASP C C   1 
ATOM   11296 O O   . ASP C 1 489 ? 117.622 135.339 196.588 1.00 95.85  ? 489 ASP C O   1 
ATOM   11297 C CB  . ASP C 1 489 ? 115.426 136.947 195.474 1.00 95.85  ? 489 ASP C CB  1 
ATOM   11298 C CG  . ASP C 1 489 ? 115.532 138.254 196.235 1.00 95.85  ? 489 ASP C CG  1 
ATOM   11299 O OD1 . ASP C 1 489 ? 116.360 139.105 195.846 1.00 95.85  ? 489 ASP C OD1 1 
ATOM   11300 O OD2 . ASP C 1 489 ? 114.790 138.430 197.223 1.00 95.85  ? 489 ASP C OD2 1 
ATOM   11301 N N   . HIS C 1 490 ? 118.966 136.879 195.625 1.00 95.00  ? 490 HIS C N   1 
ATOM   11302 C CA  . HIS C 1 490 ? 120.102 136.579 196.487 1.00 95.00  ? 490 HIS C CA  1 
ATOM   11303 C C   . HIS C 1 490 ? 119.963 137.166 197.886 1.00 95.00  ? 490 HIS C C   1 
ATOM   11304 O O   . HIS C 1 490 ? 120.660 136.714 198.802 1.00 95.00  ? 490 HIS C O   1 
ATOM   11305 C CB  . HIS C 1 490 ? 121.395 137.091 195.849 1.00 95.00  ? 490 HIS C CB  1 
ATOM   11306 C CG  . HIS C 1 490 ? 121.521 138.582 195.853 1.00 95.00  ? 490 HIS C CG  1 
ATOM   11307 N ND1 . HIS C 1 490 ? 120.687 139.401 195.124 1.00 95.00  ? 490 HIS C ND1 1 
ATOM   11308 C CD2 . HIS C 1 490 ? 122.380 139.402 196.502 1.00 95.00  ? 490 HIS C CD2 1 
ATOM   11309 C CE1 . HIS C 1 490 ? 121.029 140.662 195.321 1.00 95.00  ? 490 HIS C CE1 1 
ATOM   11310 N NE2 . HIS C 1 490 ? 122.053 140.690 196.154 1.00 95.00  ? 490 HIS C NE2 1 
ATOM   11311 N N   . ASP C 1 491 ? 119.089 138.158 198.071 1.00 97.50  ? 491 ASP C N   1 
ATOM   11312 C CA  . ASP C 1 491 ? 118.999 138.836 199.361 1.00 97.50  ? 491 ASP C CA  1 
ATOM   11313 C C   . ASP C 1 491 ? 118.459 137.922 200.452 1.00 97.50  ? 491 ASP C C   1 
ATOM   11314 O O   . ASP C 1 491 ? 118.819 138.081 201.624 1.00 97.50  ? 491 ASP C O   1 
ATOM   11315 C CB  . ASP C 1 491 ? 118.122 140.080 199.243 1.00 97.50  ? 491 ASP C CB  1 
ATOM   11316 C CG  . ASP C 1 491 ? 118.832 141.228 198.564 1.00 97.50  ? 491 ASP C CG  1 
ATOM   11317 O OD1 . ASP C 1 491 ? 120.071 141.319 198.691 1.00 97.50  ? 491 ASP C OD1 1 
ATOM   11318 O OD2 . ASP C 1 491 ? 118.151 142.042 197.907 1.00 97.50  ? 491 ASP C OD2 1 
ATOM   11319 N N   . ILE C 1 492 ? 117.589 136.978 200.095 1.00 98.32  ? 492 ILE C N   1 
ATOM   11320 C CA  . ILE C 1 492 ? 117.013 136.085 201.094 1.00 98.32  ? 492 ILE C CA  1 
ATOM   11321 C C   . ILE C 1 492 ? 118.087 135.185 201.690 1.00 98.32  ? 492 ILE C C   1 
ATOM   11322 O O   . ILE C 1 492 ? 118.126 134.956 202.903 1.00 98.32  ? 492 ILE C O   1 
ATOM   11323 C CB  . ILE C 1 492 ? 115.873 135.263 200.469 1.00 98.32  ? 492 ILE C CB  1 
ATOM   11324 C CG1 . ILE C 1 492 ? 114.817 136.190 199.871 1.00 98.32  ? 492 ILE C CG1 1 
ATOM   11325 C CG2 . ILE C 1 492 ? 115.232 134.365 201.513 1.00 98.32  ? 492 ILE C CG2 1 
ATOM   11326 C CD1 . ILE C 1 492 ? 113.817 135.475 198.997 1.00 98.32  ? 492 ILE C CD1 1 
ATOM   11327 N N   . TYR C 1 493 ? 118.972 134.663 200.848 1.00 97.03  ? 493 TYR C N   1 
ATOM   11328 C CA  . TYR C 1 493 ? 119.943 133.649 201.232 1.00 97.03  ? 493 TYR C CA  1 
ATOM   11329 C C   . TYR C 1 493 ? 121.345 134.214 201.433 1.00 97.03  ? 493 TYR C C   1 
ATOM   11330 O O   . TYR C 1 493 ? 122.284 133.444 201.671 1.00 97.03  ? 493 TYR C O   1 
ATOM   11331 C CB  . TYR C 1 493 ? 119.950 132.544 200.175 1.00 97.03  ? 493 TYR C CB  1 
ATOM   11332 C CG  . TYR C 1 493 ? 118.668 131.738 200.155 1.00 97.03  ? 493 TYR C CG  1 
ATOM   11333 C CD1 . TYR C 1 493 ? 117.765 131.802 201.209 1.00 97.03  ? 493 TYR C CD1 1 
ATOM   11334 C CD2 . TYR C 1 493 ? 118.329 130.967 199.052 1.00 97.03  ? 493 TYR C CD2 1 
ATOM   11335 C CE1 . TYR C 1 493 ? 116.592 131.075 201.192 1.00 97.03  ? 493 TYR C CE1 1 
ATOM   11336 C CE2 . TYR C 1 493 ? 117.150 130.247 199.016 1.00 97.03  ? 493 TYR C CE2 1 
ATOM   11337 C CZ  . TYR C 1 493 ? 116.285 130.305 200.089 1.00 97.03  ? 493 TYR C CZ  1 
ATOM   11338 O OH  . TYR C 1 493 ? 115.113 129.585 200.060 1.00 97.03  ? 493 TYR C OH  1 
ATOM   11339 N N   . ARG C 1 494 ? 121.499 135.538 201.337 1.00 97.86  ? 494 ARG C N   1 
ATOM   11340 C CA  . ARG C 1 494 ? 122.817 136.161 201.426 1.00 97.86  ? 494 ARG C CA  1 
ATOM   11341 C C   . ARG C 1 494 ? 123.496 135.865 202.757 1.00 97.86  ? 494 ARG C C   1 
ATOM   11342 O O   . ARG C 1 494 ? 124.674 135.494 202.794 1.00 97.86  ? 494 ARG C O   1 
ATOM   11343 C CB  . ARG C 1 494 ? 122.685 137.670 201.219 1.00 97.86  ? 494 ARG C CB  1 
ATOM   11344 C CG  . ARG C 1 494 ? 123.966 138.451 201.443 1.00 97.86  ? 494 ARG C CG  1 
ATOM   11345 C CD  . ARG C 1 494 ? 124.000 139.698 200.580 1.00 97.86  ? 494 ARG C CD  1 
ATOM   11346 N NE  . ARG C 1 494 ? 125.312 140.330 200.580 1.00 97.86  ? 494 ARG C NE  1 
ATOM   11347 C CZ  . ARG C 1 494 ? 125.509 141.641 200.564 1.00 97.86  ? 494 ARG C CZ  1 
ATOM   11348 N NH1 . ARG C 1 494 ? 124.497 142.492 200.540 1.00 97.86  ? 494 ARG C NH1 1 
ATOM   11349 N NH2 . ARG C 1 494 ? 126.754 142.110 200.574 1.00 97.86  ? 494 ARG C NH2 1 
ATOM   11350 N N   . ASP C 1 495 ? 122.774 136.044 203.866 1.00 99.64  ? 495 ASP C N   1 
ATOM   11351 C CA  . ASP C 1 495 ? 123.386 135.871 205.181 1.00 99.64  ? 495 ASP C CA  1 
ATOM   11352 C C   . ASP C 1 495 ? 123.833 134.431 205.396 1.00 99.64  ? 495 ASP C C   1 
ATOM   11353 O O   . ASP C 1 495 ? 124.944 134.178 205.878 1.00 99.64  ? 495 ASP C O   1 
ATOM   11354 C CB  . ASP C 1 495 ? 122.406 136.304 206.271 1.00 99.64  ? 495 ASP C CB  1 
ATOM   11355 C CG  . ASP C 1 495 ? 121.792 137.659 205.992 1.00 99.64  ? 495 ASP C CG  1 
ATOM   11356 O OD1 . ASP C 1 495 ? 122.552 138.642 205.876 1.00 99.64  ? 495 ASP C OD1 1 
ATOM   11357 O OD2 . ASP C 1 495 ? 120.551 137.741 205.883 1.00 99.64  ? 495 ASP C OD2 1 
ATOM   11358 N N   . GLU C 1 496 ? 122.980 133.471 205.034 1.00 98.09  ? 496 GLU C N   1 
ATOM   11359 C CA  . GLU C 1 496 ? 123.336 132.066 205.198 1.00 98.09  ? 496 GLU C CA  1 
ATOM   11360 C C   . GLU C 1 496 ? 124.521 131.690 204.317 1.00 98.09  ? 496 GLU C C   1 
ATOM   11361 O O   . GLU C 1 496 ? 125.424 130.967 204.758 1.00 98.09  ? 496 GLU C O   1 
ATOM   11362 C CB  . GLU C 1 496 ? 122.130 131.180 204.890 1.00 98.09  ? 496 GLU C CB  1 
ATOM   11363 C CG  . GLU C 1 496 ? 122.467 129.711 204.712 1.00 98.09  ? 496 GLU C CG  1 
ATOM   11364 C CD  . GLU C 1 496 ? 121.248 128.865 204.405 1.00 98.09  ? 496 GLU C CD  1 
ATOM   11365 O OE1 . GLU C 1 496 ? 120.157 129.439 204.208 1.00 98.09  ? 496 GLU C OE1 1 
ATOM   11366 O OE2 . GLU C 1 496 ? 121.381 127.624 204.365 1.00 98.09  ? 496 GLU C OE2 1 
ATOM   11367 N N   . ALA C 1 497 ? 124.545 132.178 203.074 1.00 99.28  ? 497 ALA C N   1 
ATOM   11368 C CA  . ALA C 1 497 ? 125.666 131.875 202.191 1.00 99.28  ? 497 ALA C CA  1 
ATOM   11369 C C   . ALA C 1 497 ? 126.965 132.470 202.719 1.00 99.28  ? 497 ALA C C   1 
ATOM   11370 O O   . ALA C 1 497 ? 128.015 131.818 202.683 1.00 99.28  ? 497 ALA C O   1 
ATOM   11371 C CB  . ALA C 1 497 ? 125.375 132.383 200.782 1.00 99.28  ? 497 ALA C CB  1 
ATOM   11372 N N   . LEU C 1 498 ? 126.916 133.711 203.211 1.00 99.06  ? 498 LEU C N   1 
ATOM   11373 C CA  . LEU C 1 498 ? 128.118 134.342 203.746 1.00 99.06  ? 498 LEU C CA  1 
ATOM   11374 C C   . LEU C 1 498 ? 128.606 133.625 204.998 1.00 99.06  ? 498 LEU C C   1 
ATOM   11375 O O   . LEU C 1 498 ? 129.816 133.482 205.207 1.00 99.06  ? 498 LEU C O   1 
ATOM   11376 C CB  . LEU C 1 498 ? 127.854 135.818 204.039 1.00 99.06  ? 498 LEU C CB  1 
ATOM   11377 C CG  . LEU C 1 498 ? 127.775 136.738 202.820 1.00 99.06  ? 498 LEU C CG  1 
ATOM   11378 C CD1 . LEU C 1 498 ? 127.374 138.143 203.231 1.00 99.06  ? 498 LEU C CD1 1 
ATOM   11379 C CD2 . LEU C 1 498 ? 129.099 136.751 202.074 1.00 99.06  ? 498 LEU C CD2 1 
ATOM   11380 N N   . ASN C 1 499 ? 127.680 133.177 205.849 1.00 99.30  ? 499 ASN C N   1 
ATOM   11381 C CA  . ASN C 1 499 ? 128.075 132.415 207.029 1.00 99.30  ? 499 ASN C CA  1 
ATOM   11382 C C   . ASN C 1 499 ? 128.714 131.087 206.638 1.00 99.30  ? 499 ASN C C   1 
ATOM   11383 O O   . ASN C 1 499 ? 129.707 130.667 207.242 1.00 99.30  ? 499 ASN C O   1 
ATOM   11384 C CB  . ASN C 1 499 ? 126.867 132.184 207.936 1.00 99.30  ? 499 ASN C CB  1 
ATOM   11385 C CG  . ASN C 1 499 ? 126.374 133.462 208.585 1.00 99.30  ? 499 ASN C CG  1 
ATOM   11386 O OD1 . ASN C 1 499 ? 127.126 134.424 208.738 1.00 99.30  ? 499 ASN C OD1 1 
ATOM   11387 N ND2 . ASN C 1 499 ? 125.105 133.476 208.973 1.00 99.30  ? 499 ASN C ND2 1 
ATOM   11388 N N   . ASN C 1 500 ? 128.152 130.409 205.634 1.00 98.58  ? 500 ASN C N   1 
ATOM   11389 C CA  . ASN C 1 500 ? 128.722 129.141 205.187 1.00 98.58  ? 500 ASN C CA  1 
ATOM   11390 C C   . ASN C 1 500 ? 130.107 129.332 204.581 1.00 98.58  ? 500 ASN C C   1 
ATOM   11391 O O   . ASN C 1 500 ? 131.014 128.528 204.829 1.00 98.58  ? 500 ASN C O   1 
ATOM   11392 C CB  . ASN C 1 500 ? 127.786 128.469 204.183 1.00 98.58  ? 500 ASN C CB  1 
ATOM   11393 C CG  . ASN C 1 500 ? 126.763 127.571 204.850 1.00 98.58  ? 500 ASN C CG  1 
ATOM   11394 O OD1 . ASN C 1 500 ? 127.101 126.759 205.711 1.00 98.58  ? 500 ASN C OD1 1 
ATOM   11395 N ND2 . ASN C 1 500 ? 125.503 127.712 204.455 1.00 98.58  ? 500 ASN C ND2 1 
ATOM   11396 N N   . ARG C 1 501 ? 130.290 130.384 203.779 1.00 96.11  ? 501 ARG C N   1 
ATOM   11397 C CA  . ARG C 1 501 ? 131.583 130.605 203.137 1.00 96.11  ? 501 ARG C CA  1 
ATOM   11398 C C   . ARG C 1 501 ? 132.654 130.984 204.152 1.00 96.11  ? 501 ARG C C   1 
ATOM   11399 O O   . ARG C 1 501 ? 133.801 130.533 204.049 1.00 96.11  ? 501 ARG C O   1 
ATOM   11400 C CB  . ARG C 1 501 ? 131.459 131.682 202.060 1.00 96.11  ? 501 ARG C CB  1 
ATOM   11401 C CG  . ARG C 1 501 ? 130.686 131.240 200.831 1.00 96.11  ? 501 ARG C CG  1 
ATOM   11402 C CD  . ARG C 1 501 ? 130.573 132.360 199.811 1.00 96.11  ? 501 ARG C CD  1 
ATOM   11403 N NE  . ARG C 1 501 ? 131.829 132.588 199.107 1.00 96.11  ? 501 ARG C NE  1 
ATOM   11404 C CZ  . ARG C 1 501 ? 132.031 133.566 198.235 1.00 96.11  ? 501 ARG C CZ  1 
ATOM   11405 N NH1 . ARG C 1 501 ? 131.077 134.432 197.935 1.00 96.11  ? 501 ARG C NH1 1 
ATOM   11406 N NH2 . ARG C 1 501 ? 133.219 133.679 197.650 1.00 96.11  ? 501 ARG C NH2 1 
ATOM   11407 N N   . PHE C 1 502 ? 132.306 131.809 205.133 1.00 98.48  ? 502 PHE C N   1 
ATOM   11408 C CA  . PHE C 1 502 ? 133.270 132.255 206.132 1.00 98.48  ? 502 PHE C CA  1 
ATOM   11409 C C   . PHE C 1 502 ? 132.899 131.742 207.519 1.00 98.48  ? 502 PHE C C   1 
ATOM   11410 O O   . PHE C 1 502 ? 133.271 130.633 207.901 1.00 98.48  ? 502 PHE C O   1 
ATOM   11411 C CB  . PHE C 1 502 ? 133.366 133.783 206.143 1.00 98.48  ? 502 PHE C CB  1 
ATOM   11412 C CG  . PHE C 1 502 ? 133.629 134.386 204.792 1.00 98.48  ? 502 PHE C CG  1 
ATOM   11413 C CD1 . PHE C 1 502 ? 134.490 133.771 203.897 1.00 98.48  ? 502 PHE C CD1 1 
ATOM   11414 C CD2 . PHE C 1 502 ? 133.015 135.568 204.415 1.00 98.48  ? 502 PHE C CD2 1 
ATOM   11415 C CE1 . PHE C 1 502 ? 134.731 134.323 202.654 1.00 98.48  ? 502 PHE C CE1 1 
ATOM   11416 C CE2 . PHE C 1 502 ? 133.254 136.125 203.173 1.00 98.48  ? 502 PHE C CE2 1 
ATOM   11417 C CZ  . PHE C 1 502 ? 134.113 135.501 202.292 1.00 98.48  ? 502 PHE C CZ  1 
HETATM 11418 C C1  . NAG D 2 .   ? 139.588 112.723 89.823  1.00 31.97  ? 1   NAG D C1  1 
HETATM 11419 C C2  . NAG D 2 .   ? 138.646 111.998 88.865  1.00 31.97  ? 1   NAG D C2  1 
HETATM 11420 C C3  . NAG D 2 .   ? 137.457 111.422 89.629  1.00 31.97  ? 1   NAG D C3  1 
HETATM 11421 C C4  . NAG D 2 .   ? 137.928 110.569 90.799  1.00 31.97  ? 1   NAG D C4  1 
HETATM 11422 C C5  . NAG D 2 .   ? 138.917 111.348 91.662  1.00 31.97  ? 1   NAG D C5  1 
HETATM 11423 C C6  . NAG D 2 .   ? 139.538 110.509 92.753  1.00 31.97  ? 1   NAG D C6  1 
HETATM 11424 C C7  . NAG D 2 .   ? 138.658 112.838 86.558  1.00 31.97  ? 1   NAG D C7  1 
HETATM 11425 C C8  . NAG D 2 .   ? 138.078 113.833 85.600  1.00 31.97  ? 1   NAG D C8  1 
HETATM 11426 N N2  . NAG D 2 .   ? 138.192 112.889 87.810  1.00 31.97  ? 1   NAG D N2  1 
HETATM 11427 O O3  . NAG D 2 .   ? 136.665 110.638 88.744  1.00 31.97  ? 1   NAG D O3  1 
HETATM 11428 O O4  . NAG D 2 .   ? 136.812 110.208 91.606  1.00 31.97  ? 1   NAG D O4  1 
HETATM 11429 O O5  . NAG D 2 .   ? 139.998 111.832 90.854  1.00 31.97  ? 1   NAG D O5  1 
HETATM 11430 O O6  . NAG D 2 .   ? 140.843 110.081 92.393  1.00 31.97  ? 1   NAG D O6  1 
HETATM 11431 O O7  . NAG D 2 .   ? 139.510 112.025 86.215  1.00 31.97  ? 1   NAG D O7  1 
HETATM 11432 C C1  . NAG D 2 .   ? 136.521 108.804 91.486  1.00 32.60  ? 2   NAG D C1  1 
HETATM 11433 C C2  . NAG D 2 .   ? 135.979 108.321 92.830  1.00 32.60  ? 2   NAG D C2  1 
HETATM 11434 C C3  . NAG D 2 .   ? 135.575 106.852 92.742  1.00 32.60  ? 2   NAG D C3  1 
HETATM 11435 C C4  . NAG D 2 .   ? 134.619 106.628 91.578  1.00 32.60  ? 2   NAG D C4  1 
HETATM 11436 C C5  . NAG D 2 .   ? 135.224 107.179 90.291  1.00 32.60  ? 2   NAG D C5  1 
HETATM 11437 C C6  . NAG D 2 .   ? 134.282 107.101 89.113  1.00 32.60  ? 2   NAG D C6  1 
HETATM 11438 C C7  . NAG D 2 .   ? 136.751 109.321 94.935  1.00 32.60  ? 2   NAG D C7  1 
HETATM 11439 C C8  . NAG D 2 .   ? 137.867 109.404 95.930  1.00 32.60  ? 2   NAG D C8  1 
HETATM 11440 N N2  . NAG D 2 .   ? 136.958 108.517 93.887  1.00 32.60  ? 2   NAG D N2  1 
HETATM 11441 O O3  . NAG D 2 .   ? 134.956 106.462 93.962  1.00 32.60  ? 2   NAG D O3  1 
HETATM 11442 O O4  . NAG D 2 .   ? 134.374 105.237 91.413  1.00 32.60  ? 2   NAG D O4  1 
HETATM 11443 O O5  . NAG D 2 .   ? 135.557 108.564 90.464  1.00 32.60  ? 2   NAG D O5  1 
HETATM 11444 O O6  . NAG D 2 .   ? 134.803 107.789 87.985  1.00 32.60  ? 2   NAG D O6  1 
HETATM 11445 O O7  . NAG D 2 .   ? 135.709 109.952 95.072  1.00 32.60  ? 2   NAG D O7  1 
HETATM 11446 C C1  . BMA D 2 .   ? 133.026 104.932 91.819  1.00 45.95  ? 3   BMA D C1  1 
HETATM 11447 C C2  . BMA D 2 .   ? 132.489 103.846 90.861  1.00 45.95  ? 3   BMA D C2  1 
HETATM 11448 C C3  . BMA D 2 .   ? 131.141 103.314 91.355  1.00 45.95  ? 3   BMA D C3  1 
HETATM 11449 C C4  . BMA D 2 .   ? 131.192 102.956 92.847  1.00 45.95  ? 3   BMA D C4  1 
HETATM 11450 C C5  . BMA D 2 .   ? 131.695 104.157 93.653  1.00 45.95  ? 3   BMA D C5  1 
HETATM 11451 C C6  . BMA D 2 .   ? 131.806 103.864 95.136  1.00 45.95  ? 3   BMA D C6  1 
HETATM 11452 O O2  . BMA D 2 .   ? 133.372 102.738 90.816  1.00 45.95  ? 3   BMA D O2  1 
HETATM 11453 O O3  . BMA D 2 .   ? 130.713 102.183 90.600  1.00 45.95  ? 3   BMA D O3  1 
HETATM 11454 O O4  . BMA D 2 .   ? 129.902 102.590 93.303  1.00 45.95  ? 3   BMA D O4  1 
HETATM 11455 O O5  . BMA D 2 .   ? 133.000 104.496 93.171  1.00 45.95  ? 3   BMA D O5  1 
HETATM 11456 O O6  . BMA D 2 .   ? 132.881 102.951 95.325  1.00 45.95  ? 3   BMA D O6  1 
HETATM 11457 C C1  . MAN D 2 .   ? 130.390 102.600 89.256  1.00 58.41  ? 4   MAN D C1  1 
HETATM 11458 C C2  . MAN D 2 .   ? 128.988 102.028 88.907  1.00 58.41  ? 4   MAN D C2  1 
HETATM 11459 C C3  . MAN D 2 .   ? 129.064 100.517 88.680  1.00 58.41  ? 4   MAN D C3  1 
HETATM 11460 C C4  . MAN D 2 .   ? 130.192 100.159 87.703  1.00 58.41  ? 4   MAN D C4  1 
HETATM 11461 C C5  . MAN D 2 .   ? 131.514 100.728 88.224  1.00 58.41  ? 4   MAN D C5  1 
HETATM 11462 C C6  . MAN D 2 .   ? 132.685 100.449 87.302  1.00 58.41  ? 4   MAN D C6  1 
HETATM 11463 O O2  . MAN D 2 .   ? 128.493 102.577 87.684  1.00 58.41  ? 4   MAN D O2  1 
HETATM 11464 O O3  . MAN D 2 .   ? 127.826 99.996  88.209  1.00 58.41  ? 4   MAN D O3  1 
HETATM 11465 O O4  . MAN D 2 .   ? 130.300 98.751  87.582  1.00 58.41  ? 4   MAN D O4  1 
HETATM 11466 O O5  . MAN D 2 .   ? 131.383 102.157 88.344  1.00 58.41  ? 4   MAN D O5  1 
HETATM 11467 O O6  . MAN D 2 .   ? 132.849 99.038  87.208  1.00 58.41  ? 4   MAN D O6  1 
HETATM 11468 C C1  . MAN D 2 .   ? 132.785 102.359 96.637  1.00 57.72  ? 5   MAN D C1  1 
HETATM 11469 C C2  . MAN D 2 .   ? 134.164 101.734 96.965  1.00 57.72  ? 5   MAN D C2  1 
HETATM 11470 C C3  . MAN D 2 .   ? 134.409 100.507 96.087  1.00 57.72  ? 5   MAN D C3  1 
HETATM 11471 C C4  . MAN D 2 .   ? 133.223 99.533  96.156  1.00 57.72  ? 5   MAN D C4  1 
HETATM 11472 C C5  . MAN D 2 .   ? 131.930 100.265 95.785  1.00 57.72  ? 5   MAN D C5  1 
HETATM 11473 C C6  . MAN D 2 .   ? 130.701 99.390  95.912  1.00 57.72  ? 5   MAN D C6  1 
HETATM 11474 O O2  . MAN D 2 .   ? 134.214 101.259 98.312  1.00 57.72  ? 5   MAN D O2  1 
HETATM 11475 O O3  . MAN D 2 .   ? 135.613 99.836  96.445  1.00 57.72  ? 5   MAN D O3  1 
HETATM 11476 O O4  . MAN D 2 .   ? 133.428 98.460  95.252  1.00 57.72  ? 5   MAN D O4  1 
HETATM 11477 O O5  . MAN D 2 .   ? 131.753 101.390 96.673  1.00 57.72  ? 5   MAN D O5  1 
HETATM 11478 O O6  . MAN D 2 .   ? 130.402 99.247  97.296  1.00 57.72  ? 5   MAN D O6  1 
HETATM 11479 C C1  . NAG E 3 .   ? 159.339 141.462 132.781 1.00 38.64  ? 1   NAG E C1  1 
HETATM 11480 C C2  . NAG E 3 .   ? 159.617 142.735 133.575 1.00 38.64  ? 1   NAG E C2  1 
HETATM 11481 C C3  . NAG E 3 .   ? 158.565 143.795 133.258 1.00 38.64  ? 1   NAG E C3  1 
HETATM 11482 C C4  . NAG E 3 .   ? 158.443 144.010 131.755 1.00 38.64  ? 1   NAG E C4  1 
HETATM 11483 C C5  . NAG E 3 .   ? 158.245 142.675 131.038 1.00 38.64  ? 1   NAG E C5  1 
HETATM 11484 C C6  . NAG E 3 .   ? 158.271 142.797 129.532 1.00 38.64  ? 1   NAG E C6  1 
HETATM 11485 C C7  . NAG E 3 .   ? 160.764 142.121 135.659 1.00 38.64  ? 1   NAG E C7  1 
HETATM 11486 C C8  . NAG E 3 .   ? 160.611 141.872 137.128 1.00 38.64  ? 1   NAG E C8  1 
HETATM 11487 N N2  . NAG E 3 .   ? 159.649 142.461 135.003 1.00 38.64  ? 1   NAG E N2  1 
HETATM 11488 O O3  . NAG E 3 .   ? 158.917 145.018 133.895 1.00 38.64  ? 1   NAG E O3  1 
HETATM 11489 O O4  . NAG E 3 .   ? 157.323 144.848 131.492 1.00 38.64  ? 1   NAG E O4  1 
HETATM 11490 O O5  . NAG E 3 .   ? 159.296 141.765 131.393 1.00 38.64  ? 1   NAG E O5  1 
HETATM 11491 O O6  . NAG E 3 .   ? 157.048 142.361 128.955 1.00 38.64  ? 1   NAG E O6  1 
HETATM 11492 O O7  . NAG E 3 .   ? 161.846 142.018 135.091 1.00 38.64  ? 1   NAG E O7  1 
HETATM 11493 C C1  . NAG E 3 .   ? 157.724 146.023 130.754 1.00 47.02  ? 2   NAG E C1  1 
HETATM 11494 C C2  . NAG E 3 .   ? 156.457 146.766 130.329 1.00 47.02  ? 2   NAG E C2  1 
HETATM 11495 C C3  . NAG E 3 .   ? 156.824 148.034 129.565 1.00 47.02  ? 2   NAG E C3  1 
HETATM 11496 C C4  . NAG E 3 .   ? 157.784 148.888 130.383 1.00 47.02  ? 2   NAG E C4  1 
HETATM 11497 C C5  . NAG E 3 .   ? 158.991 148.060 130.820 1.00 47.02  ? 2   NAG E C5  1 
HETATM 11498 C C6  . NAG E 3 .   ? 159.922 148.813 131.741 1.00 47.02  ? 2   NAG E C6  1 
HETATM 11499 C C7  . NAG E 3 .   ? 154.432 145.429 129.960 1.00 47.02  ? 2   NAG E C7  1 
HETATM 11500 C C8  . NAG E 3 .   ? 153.676 144.566 128.996 1.00 47.02  ? 2   NAG E C8  1 
HETATM 11501 N N2  . NAG E 3 .   ? 155.598 145.914 129.523 1.00 47.02  ? 2   NAG E N2  1 
HETATM 11502 O O3  . NAG E 3 .   ? 155.641 148.771 129.279 1.00 47.02  ? 2   NAG E O3  1 
HETATM 11503 O O4  . NAG E 3 .   ? 158.231 149.994 129.608 1.00 47.02  ? 2   NAG E O4  1 
HETATM 11504 O O5  . NAG E 3 .   ? 158.553 146.895 131.536 1.00 47.02  ? 2   NAG E O5  1 
HETATM 11505 O O6  . NAG E 3 .   ? 159.261 149.217 132.932 1.00 47.02  ? 2   NAG E O6  1 
HETATM 11506 O O7  . NAG E 3 .   ? 154.006 145.676 131.083 1.00 47.02  ? 2   NAG E O7  1 
HETATM 11507 C C1  . NAG F 2 .   ? 155.338 148.732 89.135  1.00 31.69  ? 1   NAG F C1  1 
HETATM 11508 C C2  . NAG F 2 .   ? 156.521 148.360 88.252  1.00 31.69  ? 1   NAG F C2  1 
HETATM 11509 C C3  . NAG F 2 .   ? 157.608 147.688 89.086  1.00 31.69  ? 1   NAG F C3  1 
HETATM 11510 C C4  . NAG F 2 .   ? 157.981 148.555 90.282  1.00 31.69  ? 1   NAG F C4  1 
HETATM 11511 C C5  . NAG F 2 .   ? 156.732 148.959 91.063  1.00 31.69  ? 1   NAG F C5  1 
HETATM 11512 C C6  . NAG F 2 .   ? 157.020 149.952 92.164  1.00 31.69  ? 1   NAG F C6  1 
HETATM 11513 C C7  . NAG F 2 .   ? 155.952 147.927 85.905  1.00 31.69  ? 1   NAG F C7  1 
HETATM 11514 C C8  . NAG F 2 .   ? 155.517 146.899 84.905  1.00 31.69  ? 1   NAG F C8  1 
HETATM 11515 N N2  . NAG F 2 .   ? 156.106 147.495 87.160  1.00 31.69  ? 1   NAG F N2  1 
HETATM 11516 O O3  . NAG F 2 .   ? 158.751 147.463 88.269  1.00 31.69  ? 1   NAG F O3  1 
HETATM 11517 O O4  . NAG F 2 .   ? 158.836 147.828 91.158  1.00 31.69  ? 1   NAG F O4  1 
HETATM 11518 O O5  . NAG F 2 .   ? 155.778 149.579 90.190  1.00 31.69  ? 1   NAG F O5  1 
HETATM 11519 O O6  . NAG F 2 .   ? 157.018 151.284 91.669  1.00 31.69  ? 1   NAG F O6  1 
HETATM 11520 O O7  . NAG F 2 .   ? 156.156 149.095 85.590  1.00 31.69  ? 1   NAG F O7  1 
HETATM 11521 C C1  . NAG F 2 .   ? 160.207 148.235 90.997  1.00 32.86  ? 2   NAG F C1  1 
HETATM 11522 C C2  . NAG F 2 .   ? 160.921 148.064 92.335  1.00 32.86  ? 2   NAG F C2  1 
HETATM 11523 C C3  . NAG F 2 .   ? 162.402 148.403 92.194  1.00 32.86  ? 2   NAG F C3  1 
HETATM 11524 C C4  . NAG F 2 .   ? 163.029 147.610 91.056  1.00 32.86  ? 2   NAG F C4  1 
HETATM 11525 C C5  . NAG F 2 .   ? 162.224 147.800 89.775  1.00 32.86  ? 2   NAG F C5  1 
HETATM 11526 C C6  . NAG F 2 .   ? 162.714 146.936 88.637  1.00 32.86  ? 2   NAG F C6  1 
HETATM 11527 C C7  . NAG F 2 .   ? 159.576 148.386 94.364  1.00 32.86  ? 2   NAG F C7  1 
HETATM 11528 C C8  . NAG F 2 .   ? 159.019 149.382 95.334  1.00 32.86  ? 2   NAG F C8  1 
HETATM 11529 N N2  . NAG F 2 .   ? 160.306 148.888 93.363  1.00 32.86  ? 2   NAG F N2  1 
HETATM 11530 O O3  . NAG F 2 .   ? 163.069 148.110 93.417  1.00 32.86  ? 2   NAG F O3  1 
HETATM 11531 O O4  . NAG F 2 .   ? 164.359 148.062 90.828  1.00 32.86  ? 2   NAG F O4  1 
HETATM 11532 O O5  . NAG F 2 .   ? 160.854 147.444 90.003  1.00 32.86  ? 2   NAG F O5  1 
HETATM 11533 O O6  . NAG F 2 .   ? 162.054 147.256 87.420  1.00 32.86  ? 2   NAG F O6  1 
HETATM 11534 O O7  . NAG F 2 .   ? 159.373 147.183 94.479  1.00 32.86  ? 2   NAG F O7  1 
HETATM 11535 C C1  . BMA F 2 .   ? 165.303 147.084 91.302  1.00 48.27  ? 3   BMA F C1  1 
HETATM 11536 C C2  . BMA F 2 .   ? 166.507 147.100 90.329  1.00 48.27  ? 3   BMA F C2  1 
HETATM 11537 C C3  . BMA F 2 .   ? 167.695 146.319 90.904  1.00 48.27  ? 3   BMA F C3  1 
HETATM 11538 C C4  . BMA F 2 .   ? 167.951 146.674 92.374  1.00 48.27  ? 3   BMA F C4  1 
HETATM 11539 C C5  . BMA F 2 .   ? 166.665 146.493 93.179  1.00 48.27  ? 3   BMA F C5  1 
HETATM 11540 C C6  . BMA F 2 .   ? 166.839 146.831 94.647  1.00 48.27  ? 3   BMA F C6  1 
HETATM 11541 O O2  . BMA F 2 .   ? 166.958 148.428 90.112  1.00 48.27  ? 3   BMA F O2  1 
HETATM 11542 O O3  . BMA F 2 .   ? 168.878 146.549 90.148  1.00 48.27  ? 3   BMA F O3  1 
HETATM 11543 O O4  . BMA F 2 .   ? 168.963 145.838 92.905  1.00 48.27  ? 3   BMA F O4  1 
HETATM 11544 O O5  . BMA F 2 .   ? 165.687 147.383 92.635  1.00 48.27  ? 3   BMA F O5  1 
HETATM 11545 O O6  . BMA F 2 .   ? 167.119 148.220 94.748  1.00 48.27  ? 3   BMA F O6  1 
HETATM 11546 C C1  . MAN F 2 .   ? 168.783 145.861 88.883  1.00 60.05  ? 4   MAN F C1  1 
HETATM 11547 C C2  . MAN F 2 .   ? 170.107 145.082 88.679  1.00 60.05  ? 4   MAN F C2  1 
HETATM 11548 C C3  . MAN F 2 .   ? 171.255 146.055 88.406  1.00 60.05  ? 4   MAN F C3  1 
HETATM 11549 C C4  . MAN F 2 .   ? 170.893 147.031 87.278  1.00 60.05  ? 4   MAN F C4  1 
HETATM 11550 C C5  . MAN F 2 .   ? 169.589 147.760 87.626  1.00 60.05  ? 4   MAN F C5  1 
HETATM 11551 C C6  . MAN F 2 .   ? 169.121 148.701 86.530  1.00 60.05  ? 4   MAN F C6  1 
HETATM 11552 O O2  . MAN F 2 .   ? 170.040 144.233 87.533  1.00 60.05  ? 4   MAN F O2  1 
HETATM 11553 O O3  . MAN F 2 .   ? 172.462 145.368 88.093  1.00 60.05  ? 4   MAN F O3  1 
HETATM 11554 O O4  . MAN F 2 .   ? 171.932 147.980 87.110  1.00 60.05  ? 4   MAN F O4  1 
HETATM 11555 O O5  . MAN F 2 .   ? 168.549 146.782 87.831  1.00 60.05  ? 4   MAN F O5  1 
HETATM 11556 O O6  . MAN F 2 .   ? 170.142 149.666 86.306  1.00 60.05  ? 4   MAN F O6  1 
HETATM 11557 C C1  . MAN F 2 .   ? 167.326 148.559 96.135  1.00 60.94  ? 5   MAN F C1  1 
HETATM 11558 C C2  . MAN F 2 .   ? 167.083 150.085 96.288  1.00 60.94  ? 5   MAN F C2  1 
HETATM 11559 C C3  . MAN F 2 .   ? 168.221 150.874 95.639  1.00 60.94  ? 5   MAN F C3  1 
HETATM 11560 C C4  . MAN F 2 .   ? 169.590 150.368 96.118  1.00 60.94  ? 5   MAN F C4  1 
HETATM 11561 C C5  . MAN F 2 .   ? 169.703 148.864 95.857  1.00 60.94  ? 5   MAN F C5  1 
HETATM 11562 C C6  . MAN F 2 .   ? 171.002 148.273 96.361  1.00 60.94  ? 5   MAN F C6  1 
HETATM 11563 O O2  . MAN F 2 .   ? 167.076 150.478 97.662  1.00 60.94  ? 5   MAN F O2  1 
HETATM 11564 O O3  . MAN F 2 .   ? 168.101 152.271 95.888  1.00 60.94  ? 5   MAN F O3  1 
HETATM 11565 O O4  . MAN F 2 .   ? 170.624 151.042 95.420  1.00 60.94  ? 5   MAN F O4  1 
HETATM 11566 O O5  . MAN F 2 .   ? 168.631 148.192 96.546  1.00 60.94  ? 5   MAN F O5  1 
HETATM 11567 O O6  . MAN F 2 .   ? 170.838 147.962 97.739  1.00 60.94  ? 5   MAN F O6  1 
HETATM 11568 C C1  . NAG G 3 .   ? 120.250 153.900 131.555 1.00 36.14  ? 1   NAG G C1  1 
HETATM 11569 C C2  . NAG G 3 .   ? 119.070 153.490 132.439 1.00 36.14  ? 1   NAG G C2  1 
HETATM 11570 C C3  . NAG G 3 .   ? 118.741 152.014 132.228 1.00 36.14  ? 1   NAG G C3  1 
HETATM 11571 C C4  . NAG G 3 .   ? 118.554 151.706 130.748 1.00 36.14  ? 1   NAG G C4  1 
HETATM 11572 C C5  . NAG G 3 .   ? 119.756 152.205 129.949 1.00 36.14  ? 1   NAG G C5  1 
HETATM 11573 C C6  . NAG G 3 .   ? 119.591 152.048 128.455 1.00 36.14  ? 1   NAG G C6  1 
HETATM 11574 C C7  . NAG G 3 .   ? 118.816 154.765 134.522 1.00 36.14  ? 1   NAG G C7  1 
HETATM 11575 C C8  . NAG G 3 .   ? 119.228 154.885 135.958 1.00 36.14  ? 1   NAG G C8  1 
HETATM 11576 N N2  . NAG G 3 .   ? 119.358 153.752 133.840 1.00 36.14  ? 1   NAG G N2  1 
HETATM 11577 O O3  . NAG G 3 .   ? 117.558 151.683 132.946 1.00 36.14  ? 1   NAG G O3  1 
HETATM 11578 O O4  . NAG G 3 .   ? 118.425 150.300 130.573 1.00 36.14  ? 1   NAG G O4  1 
HETATM 11579 O O5  . NAG G 3 .   ? 119.954 153.604 130.195 1.00 36.14  ? 1   NAG G O5  1 
HETATM 11580 O O6  . NAG G 3 .   ? 119.870 150.717 128.042 1.00 36.14  ? 1   NAG G O6  1 
HETATM 11581 O O7  . NAG G 3 .   ? 118.028 155.549 134.005 1.00 36.14  ? 1   NAG G O7  1 
HETATM 11582 C C1  . NAG G 3 .   ? 117.172 149.982 129.931 1.00 44.13  ? 2   NAG G C1  1 
HETATM 11583 C C2  . NAG G 3 .   ? 117.089 148.461 129.806 1.00 44.13  ? 2   NAG G C2  1 
HETATM 11584 C C3  . NAG G 3 .   ? 115.767 148.058 129.160 1.00 44.13  ? 2   NAG G C3  1 
HETATM 11585 C C4  . NAG G 3 .   ? 114.596 148.676 129.912 1.00 44.13  ? 2   NAG G C4  1 
HETATM 11586 C C5  . NAG G 3 .   ? 114.786 150.184 130.045 1.00 44.13  ? 2   NAG G C5  1 
HETATM 11587 C C6  . NAG G 3 .   ? 113.720 150.841 130.891 1.00 44.13  ? 2   NAG G C6  1 
HETATM 11588 C C7  . NAG G 3 .   ? 119.208 147.242 129.600 1.00 44.13  ? 2   NAG G C7  1 
HETATM 11589 C C8  . NAG G 3 .   ? 120.288 146.783 128.668 1.00 44.13  ? 2   NAG G C8  1 
HETATM 11590 N N2  . NAG G 3 .   ? 118.212 147.939 129.044 1.00 44.13  ? 2   NAG G N2  1 
HETATM 11591 O O3  . NAG G 3 .   ? 115.653 146.639 129.165 1.00 44.13  ? 2   NAG G O3  1 
HETATM 11592 O O4  . NAG G 3 .   ? 113.381 148.417 129.218 1.00 44.13  ? 2   NAG G O4  1 
HETATM 11593 O O5  . NAG G 3 .   ? 116.046 150.466 130.672 1.00 44.13  ? 2   NAG G O5  1 
HETATM 11594 O O6  . NAG G 3 .   ? 113.597 150.205 132.156 1.00 44.13  ? 2   NAG G O6  1 
HETATM 11595 O O7  . NAG G 3 .   ? 119.235 146.992 130.800 1.00 44.13  ? 2   NAG G O7  1 
HETATM 11596 C C1  . NAG H 2 .   ? 116.202 144.276 88.594  1.00 31.92  ? 1   NAG H C1  1 
HETATM 11597 C C2  . NAG H 2 .   ? 116.093 145.453 87.629  1.00 31.92  ? 1   NAG H C2  1 
HETATM 11598 C C3  . NAG H 2 .   ? 116.097 146.771 88.400  1.00 31.92  ? 1   NAG H C3  1 
HETATM 11599 C C4  . NAG H 2 .   ? 115.036 146.762 89.493  1.00 31.92  ? 1   NAG H C4  1 
HETATM 11600 C C5  . NAG H 2 .   ? 115.177 145.517 90.364  1.00 31.92  ? 1   NAG H C5  1 
HETATM 11601 C C6  . NAG H 2 .   ? 114.065 145.372 91.375  1.00 31.92  ? 1   NAG H C6  1 
HETATM 11602 C C7  . NAG H 2 .   ? 116.999 145.077 85.378  1.00 31.92  ? 1   NAG H C7  1 
HETATM 11603 C C8  . NAG H 2 .   ? 118.225 145.109 84.516  1.00 31.92  ? 1   NAG H C8  1 
HETATM 11604 N N2  . NAG H 2 .   ? 117.172 145.429 86.656  1.00 31.92  ? 1   NAG H N2  1 
HETATM 11605 O O3  . NAG H 2 .   ? 115.860 147.844 87.497  1.00 31.92  ? 1   NAG H O3  1 
HETATM 11606 O O4  . NAG H 2 .   ? 115.192 147.909 90.321  1.00 31.92  ? 1   NAG H O4  1 
HETATM 11607 O O5  . NAG H 2 .   ? 115.145 144.339 89.546  1.00 31.92  ? 1   NAG H O5  1 
HETATM 11608 O O6  . NAG H 2 .   ? 112.945 144.698 90.818  1.00 31.92  ? 1   NAG H O6  1 
HETATM 11609 O O7  . NAG H 2 .   ? 115.902 144.749 84.937  1.00 31.92  ? 1   NAG H O7  1 
HETATM 11610 C C1  . NAG H 2 .   ? 114.180 148.892 90.030  1.00 33.25  ? 2   NAG H C1  1 
HETATM 11611 C C2  . NAG H 2 .   ? 114.025 149.795 91.254  1.00 33.25  ? 2   NAG H C2  1 
HETATM 11612 C C3  . NAG H 2 .   ? 113.026 150.914 90.969  1.00 33.25  ? 2   NAG H C3  1 
HETATM 11613 C C4  . NAG H 2 .   ? 113.393 151.654 89.688  1.00 33.25  ? 2   NAG H C4  1 
HETATM 11614 C C5  . NAG H 2 .   ? 113.563 150.660 88.545  1.00 33.25  ? 2   NAG H C5  1 
HETATM 11615 C C6  . NAG H 2 .   ? 114.029 151.299 87.258  1.00 33.25  ? 2   NAG H C6  1 
HETATM 11616 C C7  . NAG H 2 .   ? 114.464 148.538 93.319  1.00 33.25  ? 2   NAG H C7  1 
HETATM 11617 C C8  . NAG H 2 .   ? 113.856 147.768 94.450  1.00 33.25  ? 2   NAG H C8  1 
HETATM 11618 N N2  . NAG H 2 .   ? 113.608 149.026 92.415  1.00 33.25  ? 2   NAG H N2  1 
HETATM 11619 O O3  . NAG H 2 .   ? 113.010 151.814 92.071  1.00 33.25  ? 2   NAG H O3  1 
HETATM 11620 O O4  . NAG H 2 .   ? 112.355 152.565 89.343  1.00 33.25  ? 2   NAG H O4  1 
HETATM 11621 O O5  . NAG H 2 .   ? 114.545 149.676 88.899  1.00 33.25  ? 2   NAG H O5  1 
HETATM 11622 O O6  . NAG H 2 .   ? 114.619 152.570 87.488  1.00 33.25  ? 2   NAG H O6  1 
HETATM 11623 O O7  . NAG H 2 .   ? 115.673 148.711 93.225  1.00 33.25  ? 2   NAG H O7  1 
HETATM 11624 C C1  . BMA H 2 .   ? 112.690 153.912 89.737  1.00 46.44  ? 3   BMA H C1  1 
HETATM 11625 C C2  . BMA H 2 .   ? 111.986 154.871 88.746  1.00 46.44  ? 3   BMA H C2  1 
HETATM 11626 C C3  . BMA H 2 .   ? 112.054 156.320 89.240  1.00 46.44  ? 3   BMA H C3  1 
HETATM 11627 C C4  . BMA H 2 .   ? 111.676 156.431 90.720  1.00 46.44  ? 3   BMA H C4  1 
HETATM 11628 C C5  . BMA H 2 .   ? 112.538 155.479 91.547  1.00 46.44  ? 3   BMA H C5  1 
HETATM 11629 C C6  . BMA H 2 .   ? 112.200 155.526 93.023  1.00 46.44  ? 3   BMA H C6  1 
HETATM 11630 O O2  . BMA H 2 .   ? 110.610 154.546 88.629  1.00 46.44  ? 3   BMA H O2  1 
HETATM 11631 O O3  . BMA H 2 .   ? 111.210 157.170 88.474  1.00 46.44  ? 3   BMA H O3  1 
HETATM 11632 O O4  . BMA H 2 .   ? 111.874 157.761 91.170  1.00 46.44  ? 3   BMA H O4  1 
HETATM 11633 O O5  . BMA H 2 .   ? 112.291 154.148 91.080  1.00 46.44  ? 3   BMA H O5  1 
HETATM 11634 O O6  . BMA H 2 .   ? 110.859 155.088 93.178  1.00 46.44  ? 3   BMA H O6  1 
HETATM 11635 C C1  . MAN H 2 .   ? 111.852 157.483 87.221  1.00 57.19  ? 4   MAN H C1  1 
HETATM 11636 C C2  . MAN H 2 .   ? 111.884 159.026 87.084  1.00 57.19  ? 4   MAN H C2  1 
HETATM 11637 C C3  . MAN H 2 .   ? 110.474 159.561 86.856  1.00 57.19  ? 4   MAN H C3  1 
HETATM 11638 C C4  . MAN H 2 .   ? 109.787 158.820 85.697  1.00 57.19  ? 4   MAN H C4  1 
HETATM 11639 C C5  . MAN H 2 .   ? 109.794 157.312 85.974  1.00 57.19  ? 4   MAN H C5  1 
HETATM 11640 C C6  . MAN H 2 .   ? 109.195 156.499 84.841  1.00 57.19  ? 4   MAN H C6  1 
HETATM 11641 O O2  . MAN H 2 .   ? 112.637 159.432 85.940  1.00 57.19  ? 4   MAN H O2  1 
HETATM 11642 O O3  . MAN H 2 .   ? 110.478 160.962 86.609  1.00 57.19  ? 4   MAN H O3  1 
HETATM 11643 O O4  . MAN H 2 .   ? 108.446 159.268 85.562  1.00 57.19  ? 4   MAN H O4  1 
HETATM 11644 O O5  . MAN H 2 .   ? 111.158 156.876 86.146  1.00 57.19  ? 4   MAN H O5  1 
HETATM 11645 O O6  . MAN H 2 .   ? 107.894 157.007 84.569  1.00 57.19  ? 4   MAN H O6  1 
HETATM 11646 C C1  . MAN H 2 .   ? 110.503 155.137 94.575  1.00 58.27  ? 5   MAN H C1  1 
HETATM 11647 C C2  . MAN H 2 .   ? 109.277 154.205 94.780  1.00 58.27  ? 5   MAN H C2  1 
HETATM 11648 C C3  . MAN H 2 .   ? 108.026 154.834 94.162  1.00 58.27  ? 5   MAN H C3  1 
HETATM 11649 C C4  . MAN H 2 .   ? 107.837 156.273 94.658  1.00 58.27  ? 5   MAN H C4  1 
HETATM 11650 C C5  . MAN H 2 .   ? 109.091 157.087 94.327  1.00 58.27  ? 5   MAN H C5  1 
HETATM 11651 C C6  . MAN H 2 .   ? 109.015 158.519 94.816  1.00 58.27  ? 5   MAN H C6  1 
HETATM 11652 O O2  . MAN H 2 .   ? 108.981 154.031 96.168  1.00 58.27  ? 5   MAN H O2  1 
HETATM 11653 O O3  . MAN H 2 .   ? 106.858 154.063 94.425  1.00 58.27  ? 5   MAN H O3  1 
HETATM 11654 O O4  . MAN H 2 .   ? 106.714 156.860 94.024  1.00 58.27  ? 5   MAN H O4  1 
HETATM 11655 O O5  . MAN H 2 .   ? 110.226 156.471 94.971  1.00 58.27  ? 5   MAN H O5  1 
HETATM 11656 O O6  . MAN H 2 .   ? 109.517 158.558 96.148  1.00 58.27  ? 5   MAN H O6  1 
HETATM 11657 C C1  . NAG I 3 .   ? 128.990 113.601 132.717 1.00 36.76  ? 1   NAG I C1  1 
HETATM 11658 C C2  . NAG I 3 .   ? 129.896 112.826 133.672 1.00 36.76  ? 1   NAG I C2  1 
HETATM 11659 C C3  . NAG I 3 .   ? 131.349 113.255 133.484 1.00 36.76  ? 1   NAG I C3  1 
HETATM 11660 C C4  . NAG I 3 .   ? 131.757 113.165 132.019 1.00 36.76  ? 1   NAG I C4  1 
HETATM 11661 C C5  . NAG I 3 .   ? 130.751 113.901 131.136 1.00 36.76  ? 1   NAG I C5  1 
HETATM 11662 C C6  . NAG I 3 .   ? 131.016 113.729 129.659 1.00 36.76  ? 1   NAG I C6  1 
HETATM 11663 C C7  . NAG I 3 .   ? 128.615 112.214 135.676 1.00 36.76  ? 1   NAG I C7  1 
HETATM 11664 C C8  . NAG I 3 .   ? 128.303 112.562 137.100 1.00 36.76  ? 1   NAG I C8  1 
HETATM 11665 N N2  . NAG I 3 .   ? 129.483 113.018 135.053 1.00 36.76  ? 1   NAG I N2  1 
HETATM 11666 O O3  . NAG I 3 .   ? 132.192 112.425 134.275 1.00 36.76  ? 1   NAG I O3  1 
HETATM 11667 O O4  . NAG I 3 .   ? 133.040 113.758 131.850 1.00 36.76  ? 1   NAG I O4  1 
HETATM 11668 O O5  . NAG I 3 .   ? 129.427 113.403 131.378 1.00 36.76  ? 1   NAG I O5  1 
HETATM 11669 O O6  . NAG I 3 .   ? 131.750 114.827 129.134 1.00 36.76  ? 1   NAG I O6  1 
HETATM 11670 O O7  . NAG I 3 .   ? 128.103 111.250 135.116 1.00 36.76  ? 1   NAG I O7  1 
HETATM 11671 C C1  . NAG I 3 .   ? 133.991 112.792 131.356 1.00 45.92  ? 2   NAG I C1  1 
HETATM 11672 C C2  . NAG I 3 .   ? 135.274 113.535 130.984 1.00 45.92  ? 2   NAG I C2  1 
HETATM 11673 C C3  . NAG I 3 .   ? 136.330 112.551 130.491 1.00 45.92  ? 2   NAG I C3  1 
HETATM 11674 C C4  . NAG I 3 .   ? 136.545 111.447 131.517 1.00 45.92  ? 2   NAG I C4  1 
HETATM 11675 C C5  . NAG I 3 .   ? 135.214 110.788 131.870 1.00 45.92  ? 2   NAG I C5  1 
HETATM 11676 C C6  . NAG I 3 .   ? 135.336 109.761 132.971 1.00 45.92  ? 2   NAG I C6  1 
HETATM 11677 C C7  . NAG I 3 .   ? 135.040 115.864 130.246 1.00 45.92  ? 2   NAG I C7  1 
HETATM 11678 C C8  . NAG I 3 .   ? 134.750 116.774 129.092 1.00 45.92  ? 2   NAG I C8  1 
HETATM 11679 N N2  . NAG I 3 .   ? 135.016 114.554 129.980 1.00 45.92  ? 2   NAG I N2  1 
HETATM 11680 O O3  . NAG I 3 .   ? 137.551 113.243 130.256 1.00 45.92  ? 2   NAG I O3  1 
HETATM 11681 O O4  . NAG I 3 .   ? 137.434 110.465 130.997 1.00 45.92  ? 2   NAG I O4  1 
HETATM 11682 O O5  . NAG I 3 .   ? 134.285 111.781 132.331 1.00 45.92  ? 2   NAG I O5  1 
HETATM 11683 O O6  . NAG I 3 .   ? 135.947 110.312 134.129 1.00 45.92  ? 2   NAG I O6  1 
HETATM 11684 O O7  . NAG I 3 .   ? 135.284 116.295 131.368 1.00 45.92  ? 2   NAG I O7  1 
HETATM 11685 C C1  . GAL J 4 .   ? 122.722 159.503 83.193  1.00 36.96  ? 1   GAL J C1  1 
HETATM 11686 C C2  . GAL J 4 .   ? 123.015 159.967 84.625  1.00 36.96  ? 1   GAL J C2  1 
HETATM 11687 C C3  . GAL J 4 .   ? 124.135 159.130 85.237  1.00 36.96  ? 1   GAL J C3  1 
HETATM 11688 C C4  . GAL J 4 .   ? 123.771 157.639 85.175  1.00 36.96  ? 1   GAL J C4  1 
HETATM 11689 C C5  . GAL J 4 .   ? 123.378 157.263 83.740  1.00 36.96  ? 1   GAL J C5  1 
HETATM 11690 C C6  . GAL J 4 .   ? 122.809 155.855 83.593  1.00 36.96  ? 1   GAL J C6  1 
HETATM 11691 O O1  . GAL J 4 .   ? 121.672 160.234 82.626  1.00 36.96  ? 1   GAL J O1  1 
HETATM 11692 O O2  . GAL J 4 .   ? 123.427 161.323 84.669  1.00 36.96  ? 1   GAL J O2  1 
HETATM 11693 O O3  . GAL J 4 .   ? 124.339 159.464 86.606  1.00 36.96  ? 1   GAL J O3  1 
HETATM 11694 O O4  . GAL J 4 .   ? 122.702 157.357 86.060  1.00 36.96  ? 1   GAL J O4  1 
HETATM 11695 O O5  . GAL J 4 .   ? 122.363 158.136 83.211  1.00 36.96  ? 1   GAL J O5  1 
HETATM 11696 O O6  . GAL J 4 .   ? 122.665 155.502 82.228  1.00 36.96  ? 1   GAL J O6  1 
HETATM 11697 C C1  . SIA J 4 .   ? 125.190 160.269 88.519  1.00 30.16  ? 2   SIA J C1  1 
HETATM 11698 C C2  . SIA J 4 .   ? 125.593 159.785 87.065  1.00 30.16  ? 2   SIA J C2  1 
HETATM 11699 C C3  . SIA J 4 .   ? 126.428 160.756 86.226  1.00 30.16  ? 2   SIA J C3  1 
HETATM 11700 C C4  . SIA J 4 .   ? 127.884 160.858 86.667  1.00 30.16  ? 2   SIA J C4  1 
HETATM 11701 C C5  . SIA J 4 .   ? 128.532 159.474 86.700  1.00 30.16  ? 2   SIA J C5  1 
HETATM 11702 C C6  . SIA J 4 .   ? 127.668 158.447 87.480  1.00 30.16  ? 2   SIA J C6  1 
HETATM 11703 C C7  . SIA J 4 .   ? 128.077 157.006 87.101  1.00 30.16  ? 2   SIA J C7  1 
HETATM 11704 C C8  . SIA J 4 .   ? 127.198 155.965 87.825  1.00 30.16  ? 2   SIA J C8  1 
HETATM 11705 C C9  . SIA J 4 .   ? 127.996 154.707 88.139  1.00 30.16  ? 2   SIA J C9  1 
HETATM 11706 C C10 . SIA J 4 .   ? 130.959 158.882 86.888  1.00 30.16  ? 2   SIA J C10 1 
HETATM 11707 C C11 . SIA J 4 .   ? 132.224 159.129 87.706  1.00 30.16  ? 2   SIA J C11 1 
HETATM 11708 N N5  . SIA J 4 .   ? 129.856 159.549 87.316  1.00 30.16  ? 2   SIA J N5  1 
HETATM 11709 O O1A . SIA J 4 .   ? 125.134 159.319 89.347  1.00 30.16  ? 2   SIA J O1A 1 
HETATM 11710 O O1B . SIA J 4 .   ? 124.974 161.490 88.691  1.00 30.16  ? 2   SIA J O1B 1 
HETATM 11711 O O4  . SIA J 4 .   ? 128.657 161.657 85.755  1.00 30.16  ? 2   SIA J O4  1 
HETATM 11712 O O6  . SIA J 4 .   ? 126.289 158.493 87.135  1.00 30.16  ? 2   SIA J O6  1 
HETATM 11713 O O7  . SIA J 4 .   ? 128.024 156.857 85.688  1.00 30.16  ? 2   SIA J O7  1 
HETATM 11714 O O8  . SIA J 4 .   ? 126.637 156.542 89.002  1.00 30.16  ? 2   SIA J O8  1 
HETATM 11715 O O9  . SIA J 4 .   ? 127.107 153.595 88.238  1.00 30.16  ? 2   SIA J O9  1 
HETATM 11716 O O10 . SIA J 4 .   ? 130.975 158.125 85.922  1.00 30.16  ? 2   SIA J O10 1 
HETATM 11717 C C1  . GAL K 4 .   ? 165.350 135.514 84.607  1.00 36.96  ? 1   GAL K C1  1 
HETATM 11718 C C2  . GAL K 4 .   ? 165.536 135.055 86.059  1.00 36.96  ? 1   GAL K C2  1 
HETATM 11719 C C3  . GAL K 4 .   ? 164.223 134.513 86.617  1.00 36.96  ? 1   GAL K C3  1 
HETATM 11720 C C4  . GAL K 4 .   ? 163.118 135.571 86.482  1.00 36.96  ? 1   GAL K C4  1 
HETATM 11721 C C5  . GAL K 4 .   ? 163.058 136.073 85.033  1.00 36.96  ? 1   GAL K C5  1 
HETATM 11722 C C6  . GAL K 4 .   ? 162.131 137.266 84.818  1.00 36.96  ? 1   GAL K C6  1 
HETATM 11723 O O1  . GAL K 4 .   ? 166.535 136.048 84.087  1.00 36.96  ? 1   GAL K O1  1 
HETATM 11724 O O2  . GAL K 4 .   ? 166.501 134.022 86.169  1.00 36.96  ? 1   GAL K O2  1 
HETATM 11725 O O3  . GAL K 4 .   ? 164.343 134.195 88.000  1.00 36.96  ? 1   GAL K O3  1 
HETATM 11726 O O4  . GAL K 4 .   ? 163.364 136.655 87.360  1.00 36.96  ? 1   GAL K O4  1 
HETATM 11727 O O5  . GAL K 4 .   ? 164.346 136.507 84.558  1.00 36.96  ? 1   GAL K O5  1 
HETATM 11728 O O6  . GAL K 4 .   ? 161.964 137.541 83.438  1.00 36.96  ? 1   GAL K O6  1 
HETATM 11729 C C1  . SIA K 4 .   ? 164.522 133.092 89.945  1.00 30.16  ? 2   SIA K C1  1 
HETATM 11730 C C2  . SIA K 4 .   ? 163.973 132.957 88.465  1.00 30.16  ? 2   SIA K C2  1 
HETATM 11731 C C3  . SIA K 4 .   ? 164.437 131.734 87.670  1.00 30.16  ? 2   SIA K C3  1 
HETATM 11732 C C4  . SIA K 4 .   ? 163.777 130.430 88.104  1.00 30.16  ? 2   SIA K C4  1 
HETATM 11733 C C5  . SIA K 4 .   ? 162.254 130.559 88.060  1.00 30.16  ? 2   SIA K C5  1 
HETATM 11734 C C6  . SIA K 4 .   ? 161.759 131.835 88.793  1.00 30.16  ? 2   SIA K C6  1 
HETATM 11735 C C7  . SIA K 4 .   ? 160.327 132.192 88.337  1.00 30.16  ? 2   SIA K C7  1 
HETATM 11736 C C8  . SIA K 4 .   ? 159.830 133.487 89.014  1.00 30.16  ? 2   SIA K C8  1 
HETATM 11737 C C9  . SIA K 4 .   ? 158.328 133.429 89.256  1.00 30.16  ? 2   SIA K C9  1 
HETATM 11738 C C10 . SIA K 4 .   ? 160.521 128.755 88.198  1.00 30.16  ? 2   SIA K C10 1 
HETATM 11739 C C11 . SIA K 4 .   ? 160.064 127.551 89.017  1.00 30.16  ? 2   SIA K C11 1 
HETATM 11740 N N5  . SIA K 4 .   ? 161.628 129.386 88.668  1.00 30.16  ? 2   SIA K N5  1 
HETATM 11741 O O1A . SIA K 4 .   ? 163.688 133.630 90.723  1.00 30.16  ? 2   SIA K O1A 1 
HETATM 11742 O O1B . SIA K 4 .   ? 165.677 132.673 90.181  1.00 30.16  ? 2   SIA K O1B 1 
HETATM 11743 O O4  . SIA K 4 .   ? 164.126 129.344 87.228  1.00 30.16  ? 2   SIA K O4  1 
HETATM 11744 O O6  . SIA K 4 .   ? 162.504 133.000 88.462  1.00 30.16  ? 2   SIA K O6  1 
HETATM 11745 O O7  . SIA K 4 .   ? 160.293 132.286 86.919  1.00 30.16  ? 2   SIA K O7  1 
HETATM 11746 O O8  . SIA K 4 .   ? 160.552 133.707 90.224  1.00 30.16  ? 2   SIA K O8  1 
HETATM 11747 O O9  . SIA K 4 .   ? 157.805 134.756 89.305  1.00 30.16  ? 2   SIA K O9  1 
HETATM 11748 O O10 . SIA K 4 .   ? 159.906 129.101 87.194  1.00 30.16  ? 2   SIA K O10 1 
HETATM 11749 C C1  . GAL L 4 .   ? 123.235 110.535 84.353  1.00 36.96  ? 1   GAL L C1  1 
HETATM 11750 C C2  . GAL L 4 .   ? 122.675 110.632 85.777  1.00 36.96  ? 1   GAL L C2  1 
HETATM 11751 C C3  . GAL L 4 .   ? 122.836 112.050 86.318  1.00 36.96  ? 1   GAL L C3  1 
HETATM 11752 C C4  . GAL L 4 .   ? 124.310 112.476 86.246  1.00 36.96  ? 1   GAL L C4  1 
HETATM 11753 C C5  . GAL L 4 .   ? 124.844 112.249 84.825  1.00 36.96  ? 1   GAL L C5  1 
HETATM 11754 C C6  . GAL L 4 .   ? 126.349 112.452 84.680  1.00 36.96  ? 1   GAL L C6  1 
HETATM 11755 O O1  . GAL L 4 .   ? 123.131 109.233 83.852  1.00 36.96  ? 1   GAL L O1  1 
HETATM 11756 O O2  . GAL L 4 .   ? 121.294 110.314 85.827  1.00 36.96  ? 1   GAL L O2  1 
HETATM 11757 O O3  . GAL L 4 .   ? 122.433 112.131 87.681  1.00 36.96  ? 1   GAL L O3  1 
HETATM 11758 O O4  . GAL L 4 .   ? 125.081 111.738 87.177  1.00 36.96  ? 1   GAL L O4  1 
HETATM 11759 O O5  . GAL L 4 .   ? 124.598 110.908 84.363  1.00 36.96  ? 1   GAL L O5  1 
HETATM 11760 O O6  . GAL L 4 .   ? 126.738 112.433 83.317  1.00 36.96  ? 1   GAL L O6  1 
HETATM 11761 C C1  . SIA L 4 .   ? 121.295 112.564 89.565  1.00 30.16  ? 2   SIA L C1  1 
HETATM 11762 C C2  . SIA L 4 .   ? 121.525 113.079 88.084  1.00 30.16  ? 2   SIA L C2  1 
HETATM 11763 C C3  . SIA L 4 .   ? 120.274 113.273 87.224  1.00 30.16  ? 2   SIA L C3  1 
HETATM 11764 C C4  . SIA L 4 .   ? 119.455 114.505 87.594  1.00 30.16  ? 2   SIA L C4  1 
HETATM 11765 C C5  . SIA L 4 .   ? 120.330 115.758 87.570  1.00 30.16  ? 2   SIA L C5  1 
HETATM 11766 C C6  . SIA L 4 .   ? 121.645 115.563 88.372  1.00 30.16  ? 2   SIA L C6  1 
HETATM 11767 C C7  . SIA L 4 .   ? 122.692 116.616 87.946  1.00 30.16  ? 2   SIA L C7  1 
HETATM 11768 C C8  . SIA L 4 .   ? 124.027 116.413 88.693  1.00 30.16  ? 2   SIA L C8  1 
HETATM 11769 C C9  . SIA L 4 .   ? 124.716 117.748 88.943  1.00 30.16  ? 2   SIA L C9  1 
HETATM 11770 C C10 . SIA L 4 .   ? 119.630 118.162 87.627  1.00 30.16  ? 2   SIA L C10 1 
HETATM 11771 C C11 . SIA L 4 .   ? 118.777 119.176 88.386  1.00 30.16  ? 2   SIA L C11 1 
HETATM 11772 N N5  . SIA L 4 .   ? 119.599 116.898 88.121  1.00 30.16  ? 2   SIA L N5  1 
HETATM 11773 O O1A . SIA L 4 .   ? 122.139 113.033 90.377  1.00 30.16  ? 2   SIA L O1A 1 
HETATM 11774 O O1B . SIA L 4 .   ? 120.344 111.777 89.770  1.00 30.16  ? 2   SIA L O1B 1 
HETATM 11775 O O4  . SIA L 4 .   ? 118.384 114.727 86.661  1.00 30.16  ? 2   SIA L O4  1 
HETATM 11776 O O6  . SIA L 4 .   ? 122.296 114.330 88.096  1.00 30.16  ? 2   SIA L O6  1 
HETATM 11777 O O7  . SIA L 4 .   ? 122.859 116.572 86.535  1.00 30.16  ? 2   SIA L O7  1 
HETATM 11778 O O8  . SIA L 4 .   ? 123.798 115.701 89.906  1.00 30.16  ? 2   SIA L O8  1 
HETATM 11779 O O9  . SIA L 4 .   ? 126.122 117.539 89.065  1.00 30.16  ? 2   SIA L O9  1 
HETATM 11780 O O10 . SIA L 4 .   ? 120.286 118.504 86.647  1.00 30.16  ? 2   SIA L O10 1 
HETATM 11781 C C1  . NAG M 5 .   ? 158.872 133.894 160.847 1.00 51.36  ? 601 NAG A C1  1 
HETATM 11782 C C2  . NAG M 5 .   ? 159.892 133.128 161.692 1.00 51.36  ? 601 NAG A C2  1 
HETATM 11783 C C3  . NAG M 5 .   ? 160.738 132.217 160.806 1.00 51.36  ? 601 NAG A C3  1 
HETATM 11784 C C4  . NAG M 5 .   ? 159.845 131.312 159.968 1.00 51.36  ? 601 NAG A C4  1 
HETATM 11785 C C5  . NAG M 5 .   ? 158.842 132.150 159.183 1.00 51.36  ? 601 NAG A C5  1 
HETATM 11786 C C6  . NAG M 5 .   ? 157.848 131.312 158.412 1.00 51.36  ? 601 NAG A C6  1 
HETATM 11787 C C7  . NAG M 5 .   ? 161.335 133.715 163.590 1.00 51.36  ? 601 NAG A C7  1 
HETATM 11788 C C8  . NAG M 5 .   ? 162.172 134.784 164.226 1.00 51.36  ? 601 NAG A C8  1 
HETATM 11789 N N2  . NAG M 5 .   ? 160.739 134.044 162.439 1.00 51.36  ? 601 NAG A N2  1 
HETATM 11790 O O3  . NAG M 5 .   ? 161.599 131.428 161.619 1.00 51.36  ? 601 NAG A O3  1 
HETATM 11791 O O4  . NAG M 5 .   ? 160.634 130.549 159.063 1.00 51.36  ? 601 NAG A O4  1 
HETATM 11792 O O5  . NAG M 5 .   ? 158.082 132.967 160.085 1.00 51.36  ? 601 NAG A O5  1 
HETATM 11793 O O6  . NAG M 5 .   ? 156.544 131.875 158.464 1.00 51.36  ? 601 NAG A O6  1 
HETATM 11794 O O7  . NAG M 5 .   ? 161.205 132.604 164.095 1.00 51.36  ? 601 NAG A O7  1 
HETATM 11795 C C1  . NAG N 5 .   ? 126.619 158.780 159.572 1.00 56.66  ? 601 NAG B C1  1 
HETATM 11796 C C2  . NAG N 5 .   ? 126.646 160.115 160.313 1.00 56.66  ? 601 NAG B C2  1 
HETATM 11797 C C3  . NAG N 5 .   ? 126.900 161.256 159.333 1.00 56.66  ? 601 NAG B C3  1 
HETATM 11798 C C4  . NAG N 5 .   ? 128.163 160.989 158.524 1.00 56.66  ? 601 NAG B C4  1 
HETATM 11799 C C5  . NAG N 5 .   ? 128.088 159.616 157.861 1.00 56.66  ? 601 NAG B C5  1 
HETATM 11800 C C6  . NAG N 5 .   ? 129.366 159.234 157.152 1.00 56.66  ? 601 NAG B C6  1 
HETATM 11801 C C7  . NAG N 5 .   ? 125.371 160.653 162.341 1.00 56.66  ? 601 NAG B C7  1 
HETATM 11802 C C8  . NAG N 5 .   ? 124.007 160.841 162.932 1.00 56.66  ? 601 NAG B C8  1 
HETATM 11803 N N2  . NAG N 5 .   ? 125.408 160.334 161.043 1.00 56.66  ? 601 NAG B N2  1 
HETATM 11804 O O3  . NAG N 5 .   ? 127.029 162.479 160.048 1.00 56.66  ? 601 NAG B O3  1 
HETATM 11805 O O4  . NAG N 5 .   ? 128.317 161.985 157.520 1.00 56.66  ? 601 NAG B O4  1 
HETATM 11806 O O5  . NAG N 5 .   ? 127.845 158.605 158.851 1.00 56.66  ? 601 NAG B O5  1 
HETATM 11807 O O6  . NAG N 5 .   ? 129.592 157.832 157.205 1.00 56.66  ? 601 NAG B O6  1 
HETATM 11808 O O7  . NAG N 5 .   ? 126.393 160.781 163.007 1.00 56.66  ? 601 NAG B O7  1 
HETATM 11809 C C1  . NAG O 5 .   ? 121.232 118.501 160.607 1.00 49.85  ? 601 NAG C C1  1 
HETATM 11810 C C2  . NAG O 5 .   ? 119.984 118.042 161.364 1.00 49.85  ? 601 NAG C C2  1 
HETATM 11811 C C3  . NAG O 5 .   ? 118.814 117.865 160.401 1.00 49.85  ? 601 NAG C C3  1 
HETATM 11812 C C4  . NAG O 5 .   ? 118.602 119.130 159.580 1.00 49.85  ? 601 NAG C C4  1 
HETATM 11813 C C5  . NAG O 5 .   ? 119.902 119.535 158.894 1.00 49.85  ? 601 NAG C C5  1 
HETATM 11814 C C6  . NAG O 5 .   ? 119.796 120.849 158.154 1.00 49.85  ? 601 NAG C C6  1 
HETATM 11815 C C7  . NAG O 5 .   ? 119.808 116.587 163.334 1.00 49.85  ? 601 NAG C C7  1 
HETATM 11816 C C8  . NAG O 5 .   ? 120.166 115.258 163.927 1.00 49.85  ? 601 NAG C C8  1 
HETATM 11817 N N2  . NAG O 5 .   ? 120.241 116.807 162.088 1.00 49.85  ? 601 NAG C N2  1 
HETATM 11818 O O3  . NAG O 5 .   ? 117.636 117.565 161.140 1.00 49.85  ? 601 NAG C O3  1 
HETATM 11819 O O4  . NAG O 5 .   ? 117.601 118.908 158.593 1.00 49.85  ? 601 NAG C O4  1 
HETATM 11820 O O5  . NAG O 5 .   ? 120.938 119.695 159.873 1.00 49.85  ? 601 NAG C O5  1 
HETATM 11821 O O6  . NAG O 5 .   ? 120.700 120.900 157.059 1.00 49.85  ? 601 NAG C O6  1 
HETATM 11822 O O7  . NAG O 5 .   ? 119.158 117.422 163.953 1.00 49.85  ? 601 NAG C O7  1 
# 
