data_8ZW5
# 
_entry.id   8ZW5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZW5         pdb_00008zw5 10.2210/pdb8zw5/pdb 
WWPDB D_1300041592 ?            ?                   
EMDB  EMD-60516    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZW5 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus G228 mutant complexed with avian receptor analog LSTa' 
_pdbx_database_related.db_id          EMD-60516 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              gaof@im.ac.cn 
_pdbx_contact_author.name_first         'George Fu' 
_pdbx_contact_author.name_last          Gao 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3869-615X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hao, T.J.' 1 ? 
'Xie, Y.F.' 2 ? 
'Chai, Y.'  3 ? 
'Song, H.'  4 ? 
'Gao, G.F.' 5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus G228 mutant complexed with avian receptor analog LSTa' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hao, T.J.' 1 ? 
primary 'Xie, Y.F.' 2 ? 
primary 'Chai, Y.'  3 ? 
primary 'Song, H.'  4 ? 
primary 'Gao, G.F.' 5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Hemagglutinin 57124.691 3 ? ? ? 'HN/4-10 H3N8 G228 HA complexed with LSTa' 
2 branched    man 
;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
910.823   3 ? ? ? ?                                          
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3 ? ? ? ? 
4 branched    man 'N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose' 471.411   3 ? ? ? ? 
5 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   3 ? ? ? ?                                          
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;LQQNLPGKDSSTATLCLGHHSVPNGTIVKTITDDQIEVTNATELVQNSSTGKICNNPHKVLDGRDCTLIDAMLGDPHCDV
FQDEKWDLFVERSSAFSNCYPYDVPDYASLRSLIASSGTLDFITESFTWAGVSQNGGSSACKRGPANGFFSRLNWLTKSG
SSYPLLNVTMPNNYNFDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIVPNIGSRPWVRGQSGRISIYWTIVK
PGDVLVINSNGNLIAPRGFFKIRTGRSSIMRSDAPIETCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLAT
GMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKE
FSEVEGRIQDLEKYVEDTKVDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACI
ESIRNGTYDHDIYRDEALNNRFQIRGVEF
;
_entity_poly.pdbx_seq_one_letter_code_can   
;LQQNLPGKDSSTATLCLGHHSVPNGTIVKTITDDQIEVTNATELVQNSSTGKICNNPHKVLDGRDCTLIDAMLGDPHCDV
FQDEKWDLFVERSSAFSNCYPYDVPDYASLRSLIASSGTLDFITESFTWAGVSQNGGSSACKRGPANGFFSRLNWLTKSG
SSYPLLNVTMPNNYNFDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIVPNIGSRPWVRGQSGRISIYWTIVK
PGDVLVINSNGNLIAPRGFFKIRTGRSSIMRSDAPIETCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLAT
GMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKE
FSEVEGRIQDLEKYVEDTKVDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACI
ESIRNGTYDHDIYRDEALNNRFQIRGVEF
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LEU n 
1 2   GLN n 
1 3   GLN n 
1 4   ASN n 
1 5   LEU n 
1 6   PRO n 
1 7   GLY n 
1 8   LYS n 
1 9   ASP n 
1 10  SER n 
1 11  SER n 
1 12  THR n 
1 13  ALA n 
1 14  THR n 
1 15  LEU n 
1 16  CYS n 
1 17  LEU n 
1 18  GLY n 
1 19  HIS n 
1 20  HIS n 
1 21  SER n 
1 22  VAL n 
1 23  PRO n 
1 24  ASN n 
1 25  GLY n 
1 26  THR n 
1 27  ILE n 
1 28  VAL n 
1 29  LYS n 
1 30  THR n 
1 31  ILE n 
1 32  THR n 
1 33  ASP n 
1 34  ASP n 
1 35  GLN n 
1 36  ILE n 
1 37  GLU n 
1 38  VAL n 
1 39  THR n 
1 40  ASN n 
1 41  ALA n 
1 42  THR n 
1 43  GLU n 
1 44  LEU n 
1 45  VAL n 
1 46  GLN n 
1 47  ASN n 
1 48  SER n 
1 49  SER n 
1 50  THR n 
1 51  GLY n 
1 52  LYS n 
1 53  ILE n 
1 54  CYS n 
1 55  ASN n 
1 56  ASN n 
1 57  PRO n 
1 58  HIS n 
1 59  LYS n 
1 60  VAL n 
1 61  LEU n 
1 62  ASP n 
1 63  GLY n 
1 64  ARG n 
1 65  ASP n 
1 66  CYS n 
1 67  THR n 
1 68  LEU n 
1 69  ILE n 
1 70  ASP n 
1 71  ALA n 
1 72  MET n 
1 73  LEU n 
1 74  GLY n 
1 75  ASP n 
1 76  PRO n 
1 77  HIS n 
1 78  CYS n 
1 79  ASP n 
1 80  VAL n 
1 81  PHE n 
1 82  GLN n 
1 83  ASP n 
1 84  GLU n 
1 85  LYS n 
1 86  TRP n 
1 87  ASP n 
1 88  LEU n 
1 89  PHE n 
1 90  VAL n 
1 91  GLU n 
1 92  ARG n 
1 93  SER n 
1 94  SER n 
1 95  ALA n 
1 96  PHE n 
1 97  SER n 
1 98  ASN n 
1 99  CYS n 
1 100 TYR n 
1 101 PRO n 
1 102 TYR n 
1 103 ASP n 
1 104 VAL n 
1 105 PRO n 
1 106 ASP n 
1 107 TYR n 
1 108 ALA n 
1 109 SER n 
1 110 LEU n 
1 111 ARG n 
1 112 SER n 
1 113 LEU n 
1 114 ILE n 
1 115 ALA n 
1 116 SER n 
1 117 SER n 
1 118 GLY n 
1 119 THR n 
1 120 LEU n 
1 121 ASP n 
1 122 PHE n 
1 123 ILE n 
1 124 THR n 
1 125 GLU n 
1 126 SER n 
1 127 PHE n 
1 128 THR n 
1 129 TRP n 
1 130 ALA n 
1 131 GLY n 
1 132 VAL n 
1 133 SER n 
1 134 GLN n 
1 135 ASN n 
1 136 GLY n 
1 137 GLY n 
1 138 SER n 
1 139 SER n 
1 140 ALA n 
1 141 CYS n 
1 142 LYS n 
1 143 ARG n 
1 144 GLY n 
1 145 PRO n 
1 146 ALA n 
1 147 ASN n 
1 148 GLY n 
1 149 PHE n 
1 150 PHE n 
1 151 SER n 
1 152 ARG n 
1 153 LEU n 
1 154 ASN n 
1 155 TRP n 
1 156 LEU n 
1 157 THR n 
1 158 LYS n 
1 159 SER n 
1 160 GLY n 
1 161 SER n 
1 162 SER n 
1 163 TYR n 
1 164 PRO n 
1 165 LEU n 
1 166 LEU n 
1 167 ASN n 
1 168 VAL n 
1 169 THR n 
1 170 MET n 
1 171 PRO n 
1 172 ASN n 
1 173 ASN n 
1 174 TYR n 
1 175 ASN n 
1 176 PHE n 
1 177 ASP n 
1 178 LYS n 
1 179 LEU n 
1 180 TYR n 
1 181 ILE n 
1 182 TRP n 
1 183 GLY n 
1 184 VAL n 
1 185 HIS n 
1 186 HIS n 
1 187 PRO n 
1 188 SER n 
1 189 THR n 
1 190 ASN n 
1 191 GLN n 
1 192 GLU n 
1 193 GLN n 
1 194 THR n 
1 195 ASN n 
1 196 LEU n 
1 197 TYR n 
1 198 VAL n 
1 199 GLN n 
1 200 ALA n 
1 201 SER n 
1 202 GLY n 
1 203 ARG n 
1 204 VAL n 
1 205 THR n 
1 206 VAL n 
1 207 SER n 
1 208 THR n 
1 209 ARG n 
1 210 ARG n 
1 211 SER n 
1 212 GLN n 
1 213 GLN n 
1 214 THR n 
1 215 ILE n 
1 216 VAL n 
1 217 PRO n 
1 218 ASN n 
1 219 ILE n 
1 220 GLY n 
1 221 SER n 
1 222 ARG n 
1 223 PRO n 
1 224 TRP n 
1 225 VAL n 
1 226 ARG n 
1 227 GLY n 
1 228 GLN n 
1 229 SER n 
1 230 GLY n 
1 231 ARG n 
1 232 ILE n 
1 233 SER n 
1 234 ILE n 
1 235 TYR n 
1 236 TRP n 
1 237 THR n 
1 238 ILE n 
1 239 VAL n 
1 240 LYS n 
1 241 PRO n 
1 242 GLY n 
1 243 ASP n 
1 244 VAL n 
1 245 LEU n 
1 246 VAL n 
1 247 ILE n 
1 248 ASN n 
1 249 SER n 
1 250 ASN n 
1 251 GLY n 
1 252 ASN n 
1 253 LEU n 
1 254 ILE n 
1 255 ALA n 
1 256 PRO n 
1 257 ARG n 
1 258 GLY n 
1 259 PHE n 
1 260 PHE n 
1 261 LYS n 
1 262 ILE n 
1 263 ARG n 
1 264 THR n 
1 265 GLY n 
1 266 ARG n 
1 267 SER n 
1 268 SER n 
1 269 ILE n 
1 270 MET n 
1 271 ARG n 
1 272 SER n 
1 273 ASP n 
1 274 ALA n 
1 275 PRO n 
1 276 ILE n 
1 277 GLU n 
1 278 THR n 
1 279 CYS n 
1 280 ILE n 
1 281 SER n 
1 282 GLU n 
1 283 CYS n 
1 284 ILE n 
1 285 THR n 
1 286 PRO n 
1 287 ASN n 
1 288 GLY n 
1 289 SER n 
1 290 ILE n 
1 291 PRO n 
1 292 ASN n 
1 293 ASP n 
1 294 LYS n 
1 295 PRO n 
1 296 PHE n 
1 297 GLN n 
1 298 ASN n 
1 299 VAL n 
1 300 ASN n 
1 301 LYS n 
1 302 ILE n 
1 303 THR n 
1 304 TYR n 
1 305 GLY n 
1 306 ALA n 
1 307 CYS n 
1 308 PRO n 
1 309 LYS n 
1 310 TYR n 
1 311 VAL n 
1 312 LYS n 
1 313 GLN n 
1 314 ASN n 
1 315 THR n 
1 316 LEU n 
1 317 LYS n 
1 318 LEU n 
1 319 ALA n 
1 320 THR n 
1 321 GLY n 
1 322 MET n 
1 323 ARG n 
1 324 ASN n 
1 325 VAL n 
1 326 PRO n 
1 327 GLU n 
1 328 LYS n 
1 329 GLN n 
1 330 THR n 
1 331 ARG n 
1 332 GLY n 
1 333 LEU n 
1 334 PHE n 
1 335 GLY n 
1 336 ALA n 
1 337 ILE n 
1 338 ALA n 
1 339 GLY n 
1 340 PHE n 
1 341 ILE n 
1 342 GLU n 
1 343 ASN n 
1 344 GLY n 
1 345 TRP n 
1 346 GLU n 
1 347 GLY n 
1 348 MET n 
1 349 ILE n 
1 350 ASP n 
1 351 GLY n 
1 352 TRP n 
1 353 TYR n 
1 354 GLY n 
1 355 PHE n 
1 356 ARG n 
1 357 HIS n 
1 358 GLN n 
1 359 ASN n 
1 360 SER n 
1 361 GLU n 
1 362 GLY n 
1 363 THR n 
1 364 GLY n 
1 365 GLN n 
1 366 ALA n 
1 367 ALA n 
1 368 ASP n 
1 369 LEU n 
1 370 LYS n 
1 371 SER n 
1 372 THR n 
1 373 GLN n 
1 374 ALA n 
1 375 ALA n 
1 376 ILE n 
1 377 ASP n 
1 378 GLN n 
1 379 ILE n 
1 380 ASN n 
1 381 GLY n 
1 382 LYS n 
1 383 LEU n 
1 384 ASN n 
1 385 ARG n 
1 386 VAL n 
1 387 ILE n 
1 388 GLU n 
1 389 LYS n 
1 390 THR n 
1 391 ASN n 
1 392 GLU n 
1 393 LYS n 
1 394 PHE n 
1 395 HIS n 
1 396 GLN n 
1 397 ILE n 
1 398 GLU n 
1 399 LYS n 
1 400 GLU n 
1 401 PHE n 
1 402 SER n 
1 403 GLU n 
1 404 VAL n 
1 405 GLU n 
1 406 GLY n 
1 407 ARG n 
1 408 ILE n 
1 409 GLN n 
1 410 ASP n 
1 411 LEU n 
1 412 GLU n 
1 413 LYS n 
1 414 TYR n 
1 415 VAL n 
1 416 GLU n 
1 417 ASP n 
1 418 THR n 
1 419 LYS n 
1 420 VAL n 
1 421 ASP n 
1 422 LEU n 
1 423 TRP n 
1 424 SER n 
1 425 TYR n 
1 426 ASN n 
1 427 ALA n 
1 428 GLU n 
1 429 LEU n 
1 430 LEU n 
1 431 VAL n 
1 432 ALA n 
1 433 LEU n 
1 434 GLU n 
1 435 ASN n 
1 436 GLN n 
1 437 HIS n 
1 438 THR n 
1 439 ILE n 
1 440 ASP n 
1 441 LEU n 
1 442 THR n 
1 443 ASP n 
1 444 SER n 
1 445 GLU n 
1 446 MET n 
1 447 ASN n 
1 448 LYS n 
1 449 LEU n 
1 450 PHE n 
1 451 GLU n 
1 452 LYS n 
1 453 THR n 
1 454 ARG n 
1 455 ARG n 
1 456 GLN n 
1 457 LEU n 
1 458 ARG n 
1 459 GLU n 
1 460 ASN n 
1 461 ALA n 
1 462 GLU n 
1 463 ASP n 
1 464 MET n 
1 465 GLY n 
1 466 ASN n 
1 467 GLY n 
1 468 CYS n 
1 469 PHE n 
1 470 LYS n 
1 471 ILE n 
1 472 TYR n 
1 473 HIS n 
1 474 LYS n 
1 475 CYS n 
1 476 ASP n 
1 477 ASN n 
1 478 ALA n 
1 479 CYS n 
1 480 ILE n 
1 481 GLU n 
1 482 SER n 
1 483 ILE n 
1 484 ARG n 
1 485 ASN n 
1 486 GLY n 
1 487 THR n 
1 488 TYR n 
1 489 ASP n 
1 490 HIS n 
1 491 ASP n 
1 492 ILE n 
1 493 TYR n 
1 494 ARG n 
1 495 ASP n 
1 496 GLU n 
1 497 ALA n 
1 498 LEU n 
1 499 ASN n 
1 500 ASN n 
1 501 ARG n 
1 502 PHE n 
1 503 GLN n 
1 504 ILE n 
1 505 ARG n 
1 506 GLY n 
1 507 VAL n 
1 508 GLU n 
1 509 PHE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   509 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Influenza A virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     11320 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
4 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 'DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH'                                                   
'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1' WURCS PDB2Glycan 
1.1.0 
3 2 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}'    LINUCS PDB-CARE   
?     
4 3 DGlcpNAcb1-4DGlcpNAcb1-ROH                                                                                  
'Glycam Condensed Sequence' GMML       1.0   
5 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                                                       WURCS PDB2Glycan 
1.1.0 
6 3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'                                                             LINUCS PDB-CARE   
?     
7 4 DNeup5Aca2-3DGalpb1-ROH                                                                                     
'Glycam Condensed Sequence' GMML       1.0   
8 4 'WURCS=2.0/2,2,1/[a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2/a3-b2'                                     WURCS PDB2Glycan 
1.1.0 
9 4 '[][b-D-Galp]{[(3+2)][a-D-Neup5Ac]{}}'                                                                      LINUCS PDB-CARE   
?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 2 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 2 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
4 2 5 MAN C1 O1 3 BMA O6 HO6 sing ? 
5 3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
6 4 2 SIA C2 O2 1 GAL O3 HO3 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GAL 'D-saccharide, beta linking'  . beta-D-galactopyranose                   'beta-D-galactose; D-galactose; galactose' 
'C6 H12 O6'      180.156 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose                    'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6' 
180.156 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
SIA 'D-saccharide, alpha linking' . 'N-acetyl-alpha-neuraminic acid'         
'N-acetylneuraminic acid; sialic acid; alpha-sialic acid; O-SIALIC ACID' 'C11 H19 N O9'   309.270 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
GAL 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpb                         
GAL 'COMMON NAME'                         GMML     1.0 b-D-galactopyranose            
GAL 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Galp                       
GAL 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Gal                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
SIA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DNeup5Aca                      
SIA 'COMMON NAME'                         GMML     1.0 'N-acetyl-a-D-neuraminic acid' 
SIA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Neup5Ac                    
SIA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Neu5Ac                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LEU 1   1   ?   ?   ?   A . n 
A 1 2   GLN 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   ASN 4   4   ?   ?   ?   A . n 
A 1 5   LEU 5   5   ?   ?   ?   A . n 
A 1 6   PRO 6   6   ?   ?   ?   A . n 
A 1 7   GLY 7   7   ?   ?   ?   A . n 
A 1 8   LYS 8   8   ?   ?   ?   A . n 
A 1 9   ASP 9   9   ?   ?   ?   A . n 
A 1 10  SER 10  10  ?   ?   ?   A . n 
A 1 11  SER 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  12  THR THR A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  THR 14  14  14  THR THR A . n 
A 1 15  LEU 15  15  15  LEU LEU A . n 
A 1 16  CYS 16  16  16  CYS CYS A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  GLY 18  18  18  GLY GLY A . n 
A 1 19  HIS 19  19  19  HIS HIS A . n 
A 1 20  HIS 20  20  20  HIS HIS A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  PRO 23  23  23  PRO PRO A . n 
A 1 24  ASN 24  24  24  ASN ASN A . n 
A 1 25  GLY 25  25  25  GLY GLY A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  ILE 27  27  27  ILE ILE A . n 
A 1 28  VAL 28  28  28  VAL VAL A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  ILE 31  31  31  ILE ILE A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  GLU 37  37  37  GLU GLU A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  THR 39  39  39  THR THR A . n 
A 1 40  ASN 40  40  40  ASN ASN A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  THR 42  42  42  THR THR A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  VAL 45  45  45  VAL VAL A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  SER 48  48  48  SER SER A . n 
A 1 49  SER 49  49  49  SER SER A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  LYS 52  52  52  LYS LYS A . n 
A 1 53  ILE 53  53  53  ILE ILE A . n 
A 1 54  CYS 54  54  54  CYS CYS A . n 
A 1 55  ASN 55  55  55  ASN ASN A . n 
A 1 56  ASN 56  56  56  ASN ASN A . n 
A 1 57  PRO 57  57  57  PRO PRO A . n 
A 1 58  HIS 58  58  58  HIS HIS A . n 
A 1 59  LYS 59  59  59  LYS LYS A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  ASP 62  62  62  ASP ASP A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  ARG 64  64  64  ARG ARG A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  CYS 66  66  66  CYS CYS A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  ASP 70  70  70  ASP ASP A . n 
A 1 71  ALA 71  71  71  ALA ALA A . n 
A 1 72  MET 72  72  72  MET MET A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  ASP 75  75  75  ASP ASP A . n 
A 1 76  PRO 76  76  76  PRO PRO A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  CYS 78  78  78  CYS CYS A . n 
A 1 79  ASP 79  79  79  ASP ASP A . n 
A 1 80  VAL 80  80  80  VAL VAL A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  GLN 82  82  82  GLN GLN A . n 
A 1 83  ASP 83  83  83  ASP ASP A . n 
A 1 84  GLU 84  84  84  GLU GLU A . n 
A 1 85  LYS 85  85  85  LYS LYS A . n 
A 1 86  TRP 86  86  86  TRP TRP A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  PHE 89  89  89  PHE PHE A . n 
A 1 90  VAL 90  90  90  VAL VAL A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  ARG 92  92  92  ARG ARG A . n 
A 1 93  SER 93  93  93  SER SER A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  PHE 96  96  96  PHE PHE A . n 
A 1 97  SER 97  97  97  SER SER A . n 
A 1 98  ASN 98  98  98  ASN ASN A . n 
A 1 99  CYS 99  99  99  CYS CYS A . n 
A 1 100 TYR 100 100 100 TYR TYR A . n 
A 1 101 PRO 101 101 101 PRO PRO A . n 
A 1 102 TYR 102 102 102 TYR TYR A . n 
A 1 103 ASP 103 103 103 ASP ASP A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 PRO 105 105 105 PRO PRO A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 TYR 107 107 107 TYR TYR A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 ILE 114 114 114 ILE ILE A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 SER 116 116 116 SER SER A . n 
A 1 117 SER 117 117 117 SER SER A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 THR 119 119 119 THR THR A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 ASP 121 121 121 ASP ASP A . n 
A 1 122 PHE 122 122 122 PHE PHE A . n 
A 1 123 ILE 123 123 123 ILE ILE A . n 
A 1 124 THR 124 124 124 THR THR A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 SER 126 126 126 SER SER A . n 
A 1 127 PHE 127 127 127 PHE PHE A . n 
A 1 128 THR 128 128 128 THR THR A . n 
A 1 129 TRP 129 129 129 TRP TRP A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 SER 133 133 133 SER SER A . n 
A 1 134 GLN 134 134 134 GLN GLN A . n 
A 1 135 ASN 135 135 135 ASN ASN A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 CYS 141 141 141 CYS CYS A . n 
A 1 142 LYS 142 142 142 LYS LYS A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 GLY 144 144 144 GLY GLY A . n 
A 1 145 PRO 145 145 145 PRO PRO A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ASN 147 147 147 ASN ASN A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 PHE 149 149 149 PHE PHE A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 SER 151 151 151 SER SER A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 ASN 154 154 154 ASN ASN A . n 
A 1 155 TRP 155 155 155 TRP TRP A . n 
A 1 156 LEU 156 156 156 LEU LEU A . n 
A 1 157 THR 157 157 157 THR THR A . n 
A 1 158 LYS 158 158 158 LYS LYS A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 GLY 160 160 160 GLY GLY A . n 
A 1 161 SER 161 161 161 SER SER A . n 
A 1 162 SER 162 162 162 SER SER A . n 
A 1 163 TYR 163 163 163 TYR TYR A . n 
A 1 164 PRO 164 164 164 PRO PRO A . n 
A 1 165 LEU 165 165 165 LEU LEU A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 ASN 167 167 167 ASN ASN A . n 
A 1 168 VAL 168 168 168 VAL VAL A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 MET 170 170 170 MET MET A . n 
A 1 171 PRO 171 171 171 PRO PRO A . n 
A 1 172 ASN 172 172 172 ASN ASN A . n 
A 1 173 ASN 173 173 173 ASN ASN A . n 
A 1 174 TYR 174 174 174 TYR TYR A . n 
A 1 175 ASN 175 175 175 ASN ASN A . n 
A 1 176 PHE 176 176 176 PHE PHE A . n 
A 1 177 ASP 177 177 177 ASP ASP A . n 
A 1 178 LYS 178 178 178 LYS LYS A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 TYR 180 180 180 TYR TYR A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 TRP 182 182 182 TRP TRP A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 HIS 185 185 185 HIS HIS A . n 
A 1 186 HIS 186 186 186 HIS HIS A . n 
A 1 187 PRO 187 187 187 PRO PRO A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 THR 189 189 189 THR THR A . n 
A 1 190 ASN 190 190 190 ASN ASN A . n 
A 1 191 GLN 191 191 191 GLN GLN A . n 
A 1 192 GLU 192 192 192 GLU GLU A . n 
A 1 193 GLN 193 193 193 GLN GLN A . n 
A 1 194 THR 194 194 194 THR THR A . n 
A 1 195 ASN 195 195 195 ASN ASN A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 TYR 197 197 197 TYR TYR A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 GLN 199 199 199 GLN GLN A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 ARG 209 209 209 ARG ARG A . n 
A 1 210 ARG 210 210 210 ARG ARG A . n 
A 1 211 SER 211 211 211 SER SER A . n 
A 1 212 GLN 212 212 212 GLN GLN A . n 
A 1 213 GLN 213 213 213 GLN GLN A . n 
A 1 214 THR 214 214 214 THR THR A . n 
A 1 215 ILE 215 215 215 ILE ILE A . n 
A 1 216 VAL 216 216 216 VAL VAL A . n 
A 1 217 PRO 217 217 217 PRO PRO A . n 
A 1 218 ASN 218 218 218 ASN ASN A . n 
A 1 219 ILE 219 219 219 ILE ILE A . n 
A 1 220 GLY 220 220 220 GLY GLY A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 ARG 222 222 222 ARG ARG A . n 
A 1 223 PRO 223 223 223 PRO PRO A . n 
A 1 224 TRP 224 224 224 TRP TRP A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 GLN 228 228 228 GLN GLN A . n 
A 1 229 SER 229 229 229 SER SER A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 ARG 231 231 231 ARG ARG A . n 
A 1 232 ILE 232 232 232 ILE ILE A . n 
A 1 233 SER 233 233 233 SER SER A . n 
A 1 234 ILE 234 234 234 ILE ILE A . n 
A 1 235 TYR 235 235 235 TYR TYR A . n 
A 1 236 TRP 236 236 236 TRP TRP A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 LYS 240 240 240 LYS LYS A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 GLY 242 242 242 GLY GLY A . n 
A 1 243 ASP 243 243 243 ASP ASP A . n 
A 1 244 VAL 244 244 244 VAL VAL A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 ILE 247 247 247 ILE ILE A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 SER 249 249 249 SER SER A . n 
A 1 250 ASN 250 250 250 ASN ASN A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 ASN 252 252 252 ASN ASN A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ILE 254 254 254 ILE ILE A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 PRO 256 256 256 PRO PRO A . n 
A 1 257 ARG 257 257 257 ARG ARG A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 PHE 259 259 259 PHE PHE A . n 
A 1 260 PHE 260 260 260 PHE PHE A . n 
A 1 261 LYS 261 261 261 LYS LYS A . n 
A 1 262 ILE 262 262 262 ILE ILE A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 THR 264 264 264 THR THR A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 ARG 266 266 266 ARG ARG A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 SER 268 268 268 SER SER A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 MET 270 270 270 MET MET A . n 
A 1 271 ARG 271 271 271 ARG ARG A . n 
A 1 272 SER 272 272 272 SER SER A . n 
A 1 273 ASP 273 273 273 ASP ASP A . n 
A 1 274 ALA 274 274 274 ALA ALA A . n 
A 1 275 PRO 275 275 275 PRO PRO A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 GLU 277 277 277 GLU GLU A . n 
A 1 278 THR 278 278 278 THR THR A . n 
A 1 279 CYS 279 279 279 CYS CYS A . n 
A 1 280 ILE 280 280 280 ILE ILE A . n 
A 1 281 SER 281 281 281 SER SER A . n 
A 1 282 GLU 282 282 282 GLU GLU A . n 
A 1 283 CYS 283 283 283 CYS CYS A . n 
A 1 284 ILE 284 284 284 ILE ILE A . n 
A 1 285 THR 285 285 285 THR THR A . n 
A 1 286 PRO 286 286 286 PRO PRO A . n 
A 1 287 ASN 287 287 287 ASN ASN A . n 
A 1 288 GLY 288 288 288 GLY GLY A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 PRO 291 291 291 PRO PRO A . n 
A 1 292 ASN 292 292 292 ASN ASN A . n 
A 1 293 ASP 293 293 293 ASP ASP A . n 
A 1 294 LYS 294 294 294 LYS LYS A . n 
A 1 295 PRO 295 295 295 PRO PRO A . n 
A 1 296 PHE 296 296 296 PHE PHE A . n 
A 1 297 GLN 297 297 297 GLN GLN A . n 
A 1 298 ASN 298 298 298 ASN ASN A . n 
A 1 299 VAL 299 299 299 VAL VAL A . n 
A 1 300 ASN 300 300 300 ASN ASN A . n 
A 1 301 LYS 301 301 301 LYS LYS A . n 
A 1 302 ILE 302 302 302 ILE ILE A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 TYR 304 304 304 TYR TYR A . n 
A 1 305 GLY 305 305 305 GLY GLY A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 CYS 307 307 307 CYS CYS A . n 
A 1 308 PRO 308 308 308 PRO PRO A . n 
A 1 309 LYS 309 309 309 LYS LYS A . n 
A 1 310 TYR 310 310 310 TYR TYR A . n 
A 1 311 VAL 311 311 311 VAL VAL A . n 
A 1 312 LYS 312 312 312 LYS LYS A . n 
A 1 313 GLN 313 313 313 GLN GLN A . n 
A 1 314 ASN 314 314 314 ASN ASN A . n 
A 1 315 THR 315 315 315 THR THR A . n 
A 1 316 LEU 316 316 316 LEU LEU A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 LEU 318 318 318 LEU LEU A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 THR 320 320 320 THR THR A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 MET 322 322 322 MET MET A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 ASN 324 324 324 ASN ASN A . n 
A 1 325 VAL 325 325 325 VAL VAL A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 GLU 327 327 327 GLU GLU A . n 
A 1 328 LYS 328 328 ?   ?   ?   A . n 
A 1 329 GLN 329 329 ?   ?   ?   A . n 
A 1 330 THR 330 330 ?   ?   ?   A . n 
A 1 331 ARG 331 331 ?   ?   ?   A . n 
A 1 332 GLY 332 332 ?   ?   ?   A . n 
A 1 333 LEU 333 333 ?   ?   ?   A . n 
A 1 334 PHE 334 334 ?   ?   ?   A . n 
A 1 335 GLY 335 335 ?   ?   ?   A . n 
A 1 336 ALA 336 336 ?   ?   ?   A . n 
A 1 337 ILE 337 337 337 ILE ILE A . n 
A 1 338 ALA 338 338 338 ALA ALA A . n 
A 1 339 GLY 339 339 339 GLY GLY A . n 
A 1 340 PHE 340 340 340 PHE PHE A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 GLU 342 342 342 GLU GLU A . n 
A 1 343 ASN 343 343 343 ASN ASN A . n 
A 1 344 GLY 344 344 344 GLY GLY A . n 
A 1 345 TRP 345 345 345 TRP TRP A . n 
A 1 346 GLU 346 346 346 GLU GLU A . n 
A 1 347 GLY 347 347 347 GLY GLY A . n 
A 1 348 MET 348 348 348 MET MET A . n 
A 1 349 ILE 349 349 349 ILE ILE A . n 
A 1 350 ASP 350 350 350 ASP ASP A . n 
A 1 351 GLY 351 351 351 GLY GLY A . n 
A 1 352 TRP 352 352 352 TRP TRP A . n 
A 1 353 TYR 353 353 353 TYR TYR A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 PHE 355 355 355 PHE PHE A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 HIS 357 357 357 HIS HIS A . n 
A 1 358 GLN 358 358 358 GLN GLN A . n 
A 1 359 ASN 359 359 359 ASN ASN A . n 
A 1 360 SER 360 360 360 SER SER A . n 
A 1 361 GLU 361 361 361 GLU GLU A . n 
A 1 362 GLY 362 362 362 GLY GLY A . n 
A 1 363 THR 363 363 363 THR THR A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 GLN 365 365 365 GLN GLN A . n 
A 1 366 ALA 366 366 366 ALA ALA A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 ASP 368 368 368 ASP ASP A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 LYS 370 370 370 LYS LYS A . n 
A 1 371 SER 371 371 371 SER SER A . n 
A 1 372 THR 372 372 372 THR THR A . n 
A 1 373 GLN 373 373 373 GLN GLN A . n 
A 1 374 ALA 374 374 374 ALA ALA A . n 
A 1 375 ALA 375 375 375 ALA ALA A . n 
A 1 376 ILE 376 376 376 ILE ILE A . n 
A 1 377 ASP 377 377 377 ASP ASP A . n 
A 1 378 GLN 378 378 378 GLN GLN A . n 
A 1 379 ILE 379 379 379 ILE ILE A . n 
A 1 380 ASN 380 380 380 ASN ASN A . n 
A 1 381 GLY 381 381 381 GLY GLY A . n 
A 1 382 LYS 382 382 382 LYS LYS A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 ASN 384 384 384 ASN ASN A . n 
A 1 385 ARG 385 385 385 ARG ARG A . n 
A 1 386 VAL 386 386 386 VAL VAL A . n 
A 1 387 ILE 387 387 387 ILE ILE A . n 
A 1 388 GLU 388 388 388 GLU GLU A . n 
A 1 389 LYS 389 389 389 LYS LYS A . n 
A 1 390 THR 390 390 390 THR THR A . n 
A 1 391 ASN 391 391 391 ASN ASN A . n 
A 1 392 GLU 392 392 392 GLU GLU A . n 
A 1 393 LYS 393 393 393 LYS LYS A . n 
A 1 394 PHE 394 394 394 PHE PHE A . n 
A 1 395 HIS 395 395 395 HIS HIS A . n 
A 1 396 GLN 396 396 396 GLN GLN A . n 
A 1 397 ILE 397 397 397 ILE ILE A . n 
A 1 398 GLU 398 398 398 GLU GLU A . n 
A 1 399 LYS 399 399 399 LYS LYS A . n 
A 1 400 GLU 400 400 400 GLU GLU A . n 
A 1 401 PHE 401 401 401 PHE PHE A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 GLU 403 403 403 GLU GLU A . n 
A 1 404 VAL 404 404 404 VAL VAL A . n 
A 1 405 GLU 405 405 405 GLU GLU A . n 
A 1 406 GLY 406 406 406 GLY GLY A . n 
A 1 407 ARG 407 407 407 ARG ARG A . n 
A 1 408 ILE 408 408 408 ILE ILE A . n 
A 1 409 GLN 409 409 409 GLN GLN A . n 
A 1 410 ASP 410 410 410 ASP ASP A . n 
A 1 411 LEU 411 411 411 LEU LEU A . n 
A 1 412 GLU 412 412 412 GLU GLU A . n 
A 1 413 LYS 413 413 413 LYS LYS A . n 
A 1 414 TYR 414 414 414 TYR TYR A . n 
A 1 415 VAL 415 415 415 VAL VAL A . n 
A 1 416 GLU 416 416 416 GLU GLU A . n 
A 1 417 ASP 417 417 417 ASP ASP A . n 
A 1 418 THR 418 418 418 THR THR A . n 
A 1 419 LYS 419 419 419 LYS LYS A . n 
A 1 420 VAL 420 420 420 VAL VAL A . n 
A 1 421 ASP 421 421 421 ASP ASP A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 TRP 423 423 423 TRP TRP A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 TYR 425 425 425 TYR TYR A . n 
A 1 426 ASN 426 426 426 ASN ASN A . n 
A 1 427 ALA 427 427 427 ALA ALA A . n 
A 1 428 GLU 428 428 428 GLU GLU A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 LEU 430 430 430 LEU LEU A . n 
A 1 431 VAL 431 431 431 VAL VAL A . n 
A 1 432 ALA 432 432 432 ALA ALA A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 GLU 434 434 434 GLU GLU A . n 
A 1 435 ASN 435 435 435 ASN ASN A . n 
A 1 436 GLN 436 436 436 GLN GLN A . n 
A 1 437 HIS 437 437 437 HIS HIS A . n 
A 1 438 THR 438 438 438 THR THR A . n 
A 1 439 ILE 439 439 439 ILE ILE A . n 
A 1 440 ASP 440 440 440 ASP ASP A . n 
A 1 441 LEU 441 441 441 LEU LEU A . n 
A 1 442 THR 442 442 442 THR THR A . n 
A 1 443 ASP 443 443 443 ASP ASP A . n 
A 1 444 SER 444 444 444 SER SER A . n 
A 1 445 GLU 445 445 445 GLU GLU A . n 
A 1 446 MET 446 446 446 MET MET A . n 
A 1 447 ASN 447 447 447 ASN ASN A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 PHE 450 450 450 PHE PHE A . n 
A 1 451 GLU 451 451 451 GLU GLU A . n 
A 1 452 LYS 452 452 452 LYS LYS A . n 
A 1 453 THR 453 453 453 THR THR A . n 
A 1 454 ARG 454 454 454 ARG ARG A . n 
A 1 455 ARG 455 455 455 ARG ARG A . n 
A 1 456 GLN 456 456 456 GLN GLN A . n 
A 1 457 LEU 457 457 457 LEU LEU A . n 
A 1 458 ARG 458 458 458 ARG ARG A . n 
A 1 459 GLU 459 459 459 GLU GLU A . n 
A 1 460 ASN 460 460 460 ASN ASN A . n 
A 1 461 ALA 461 461 461 ALA ALA A . n 
A 1 462 GLU 462 462 462 GLU GLU A . n 
A 1 463 ASP 463 463 463 ASP ASP A . n 
A 1 464 MET 464 464 464 MET MET A . n 
A 1 465 GLY 465 465 465 GLY GLY A . n 
A 1 466 ASN 466 466 466 ASN ASN A . n 
A 1 467 GLY 467 467 467 GLY GLY A . n 
A 1 468 CYS 468 468 468 CYS CYS A . n 
A 1 469 PHE 469 469 469 PHE PHE A . n 
A 1 470 LYS 470 470 470 LYS LYS A . n 
A 1 471 ILE 471 471 471 ILE ILE A . n 
A 1 472 TYR 472 472 472 TYR TYR A . n 
A 1 473 HIS 473 473 473 HIS HIS A . n 
A 1 474 LYS 474 474 474 LYS LYS A . n 
A 1 475 CYS 475 475 475 CYS CYS A . n 
A 1 476 ASP 476 476 476 ASP ASP A . n 
A 1 477 ASN 477 477 477 ASN ASN A . n 
A 1 478 ALA 478 478 478 ALA ALA A . n 
A 1 479 CYS 479 479 479 CYS CYS A . n 
A 1 480 ILE 480 480 480 ILE ILE A . n 
A 1 481 GLU 481 481 481 GLU GLU A . n 
A 1 482 SER 482 482 482 SER SER A . n 
A 1 483 ILE 483 483 483 ILE ILE A . n 
A 1 484 ARG 484 484 484 ARG ARG A . n 
A 1 485 ASN 485 485 485 ASN ASN A . n 
A 1 486 GLY 486 486 486 GLY GLY A . n 
A 1 487 THR 487 487 487 THR THR A . n 
A 1 488 TYR 488 488 488 TYR TYR A . n 
A 1 489 ASP 489 489 489 ASP ASP A . n 
A 1 490 HIS 490 490 490 HIS HIS A . n 
A 1 491 ASP 491 491 491 ASP ASP A . n 
A 1 492 ILE 492 492 492 ILE ILE A . n 
A 1 493 TYR 493 493 493 TYR TYR A . n 
A 1 494 ARG 494 494 494 ARG ARG A . n 
A 1 495 ASP 495 495 495 ASP ASP A . n 
A 1 496 GLU 496 496 496 GLU GLU A . n 
A 1 497 ALA 497 497 497 ALA ALA A . n 
A 1 498 LEU 498 498 498 LEU LEU A . n 
A 1 499 ASN 499 499 499 ASN ASN A . n 
A 1 500 ASN 500 500 500 ASN ASN A . n 
A 1 501 ARG 501 501 501 ARG ARG A . n 
A 1 502 PHE 502 502 502 PHE PHE A . n 
A 1 503 GLN 503 503 ?   ?   ?   A . n 
A 1 504 ILE 504 504 ?   ?   ?   A . n 
A 1 505 ARG 505 505 ?   ?   ?   A . n 
A 1 506 GLY 506 506 ?   ?   ?   A . n 
A 1 507 VAL 507 507 ?   ?   ?   A . n 
A 1 508 GLU 508 508 ?   ?   ?   A . n 
A 1 509 PHE 509 509 ?   ?   ?   A . n 
B 1 1   LEU 1   1   ?   ?   ?   B . n 
B 1 2   GLN 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   ASN 4   4   ?   ?   ?   B . n 
B 1 5   LEU 5   5   ?   ?   ?   B . n 
B 1 6   PRO 6   6   ?   ?   ?   B . n 
B 1 7   GLY 7   7   ?   ?   ?   B . n 
B 1 8   LYS 8   8   ?   ?   ?   B . n 
B 1 9   ASP 9   9   ?   ?   ?   B . n 
B 1 10  SER 10  10  ?   ?   ?   B . n 
B 1 11  SER 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  12  THR THR B . n 
B 1 13  ALA 13  13  13  ALA ALA B . n 
B 1 14  THR 14  14  14  THR THR B . n 
B 1 15  LEU 15  15  15  LEU LEU B . n 
B 1 16  CYS 16  16  16  CYS CYS B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  GLY 18  18  18  GLY GLY B . n 
B 1 19  HIS 19  19  19  HIS HIS B . n 
B 1 20  HIS 20  20  20  HIS HIS B . n 
B 1 21  SER 21  21  21  SER SER B . n 
B 1 22  VAL 22  22  22  VAL VAL B . n 
B 1 23  PRO 23  23  23  PRO PRO B . n 
B 1 24  ASN 24  24  24  ASN ASN B . n 
B 1 25  GLY 25  25  25  GLY GLY B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  ILE 27  27  27  ILE ILE B . n 
B 1 28  VAL 28  28  28  VAL VAL B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  THR 30  30  30  THR THR B . n 
B 1 31  ILE 31  31  31  ILE ILE B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  ASP 33  33  33  ASP ASP B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  GLN 35  35  35  GLN GLN B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  GLU 37  37  37  GLU GLU B . n 
B 1 38  VAL 38  38  38  VAL VAL B . n 
B 1 39  THR 39  39  39  THR THR B . n 
B 1 40  ASN 40  40  40  ASN ASN B . n 
B 1 41  ALA 41  41  41  ALA ALA B . n 
B 1 42  THR 42  42  42  THR THR B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  LEU 44  44  44  LEU LEU B . n 
B 1 45  VAL 45  45  45  VAL VAL B . n 
B 1 46  GLN 46  46  46  GLN GLN B . n 
B 1 47  ASN 47  47  47  ASN ASN B . n 
B 1 48  SER 48  48  48  SER SER B . n 
B 1 49  SER 49  49  49  SER SER B . n 
B 1 50  THR 50  50  50  THR THR B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  LYS 52  52  52  LYS LYS B . n 
B 1 53  ILE 53  53  53  ILE ILE B . n 
B 1 54  CYS 54  54  54  CYS CYS B . n 
B 1 55  ASN 55  55  55  ASN ASN B . n 
B 1 56  ASN 56  56  56  ASN ASN B . n 
B 1 57  PRO 57  57  57  PRO PRO B . n 
B 1 58  HIS 58  58  58  HIS HIS B . n 
B 1 59  LYS 59  59  59  LYS LYS B . n 
B 1 60  VAL 60  60  60  VAL VAL B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  ASP 62  62  62  ASP ASP B . n 
B 1 63  GLY 63  63  63  GLY GLY B . n 
B 1 64  ARG 64  64  64  ARG ARG B . n 
B 1 65  ASP 65  65  65  ASP ASP B . n 
B 1 66  CYS 66  66  66  CYS CYS B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  ASP 70  70  70  ASP ASP B . n 
B 1 71  ALA 71  71  71  ALA ALA B . n 
B 1 72  MET 72  72  72  MET MET B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  GLY 74  74  74  GLY GLY B . n 
B 1 75  ASP 75  75  75  ASP ASP B . n 
B 1 76  PRO 76  76  76  PRO PRO B . n 
B 1 77  HIS 77  77  77  HIS HIS B . n 
B 1 78  CYS 78  78  78  CYS CYS B . n 
B 1 79  ASP 79  79  79  ASP ASP B . n 
B 1 80  VAL 80  80  80  VAL VAL B . n 
B 1 81  PHE 81  81  81  PHE PHE B . n 
B 1 82  GLN 82  82  82  GLN GLN B . n 
B 1 83  ASP 83  83  83  ASP ASP B . n 
B 1 84  GLU 84  84  84  GLU GLU B . n 
B 1 85  LYS 85  85  85  LYS LYS B . n 
B 1 86  TRP 86  86  86  TRP TRP B . n 
B 1 87  ASP 87  87  87  ASP ASP B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  PHE 89  89  89  PHE PHE B . n 
B 1 90  VAL 90  90  90  VAL VAL B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  ARG 92  92  92  ARG ARG B . n 
B 1 93  SER 93  93  93  SER SER B . n 
B 1 94  SER 94  94  94  SER SER B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  PHE 96  96  96  PHE PHE B . n 
B 1 97  SER 97  97  97  SER SER B . n 
B 1 98  ASN 98  98  98  ASN ASN B . n 
B 1 99  CYS 99  99  99  CYS CYS B . n 
B 1 100 TYR 100 100 100 TYR TYR B . n 
B 1 101 PRO 101 101 101 PRO PRO B . n 
B 1 102 TYR 102 102 102 TYR TYR B . n 
B 1 103 ASP 103 103 103 ASP ASP B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 PRO 105 105 105 PRO PRO B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 TYR 107 107 107 TYR TYR B . n 
B 1 108 ALA 108 108 108 ALA ALA B . n 
B 1 109 SER 109 109 109 SER SER B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 ARG 111 111 111 ARG ARG B . n 
B 1 112 SER 112 112 112 SER SER B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 ILE 114 114 114 ILE ILE B . n 
B 1 115 ALA 115 115 115 ALA ALA B . n 
B 1 116 SER 116 116 116 SER SER B . n 
B 1 117 SER 117 117 117 SER SER B . n 
B 1 118 GLY 118 118 118 GLY GLY B . n 
B 1 119 THR 119 119 119 THR THR B . n 
B 1 120 LEU 120 120 120 LEU LEU B . n 
B 1 121 ASP 121 121 121 ASP ASP B . n 
B 1 122 PHE 122 122 122 PHE PHE B . n 
B 1 123 ILE 123 123 123 ILE ILE B . n 
B 1 124 THR 124 124 124 THR THR B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 SER 126 126 126 SER SER B . n 
B 1 127 PHE 127 127 127 PHE PHE B . n 
B 1 128 THR 128 128 128 THR THR B . n 
B 1 129 TRP 129 129 129 TRP TRP B . n 
B 1 130 ALA 130 130 130 ALA ALA B . n 
B 1 131 GLY 131 131 131 GLY GLY B . n 
B 1 132 VAL 132 132 132 VAL VAL B . n 
B 1 133 SER 133 133 133 SER SER B . n 
B 1 134 GLN 134 134 134 GLN GLN B . n 
B 1 135 ASN 135 135 135 ASN ASN B . n 
B 1 136 GLY 136 136 136 GLY GLY B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 SER 138 138 138 SER SER B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 CYS 141 141 141 CYS CYS B . n 
B 1 142 LYS 142 142 142 LYS LYS B . n 
B 1 143 ARG 143 143 143 ARG ARG B . n 
B 1 144 GLY 144 144 144 GLY GLY B . n 
B 1 145 PRO 145 145 145 PRO PRO B . n 
B 1 146 ALA 146 146 146 ALA ALA B . n 
B 1 147 ASN 147 147 147 ASN ASN B . n 
B 1 148 GLY 148 148 148 GLY GLY B . n 
B 1 149 PHE 149 149 149 PHE PHE B . n 
B 1 150 PHE 150 150 150 PHE PHE B . n 
B 1 151 SER 151 151 151 SER SER B . n 
B 1 152 ARG 152 152 152 ARG ARG B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 ASN 154 154 154 ASN ASN B . n 
B 1 155 TRP 155 155 155 TRP TRP B . n 
B 1 156 LEU 156 156 156 LEU LEU B . n 
B 1 157 THR 157 157 157 THR THR B . n 
B 1 158 LYS 158 158 158 LYS LYS B . n 
B 1 159 SER 159 159 159 SER SER B . n 
B 1 160 GLY 160 160 160 GLY GLY B . n 
B 1 161 SER 161 161 161 SER SER B . n 
B 1 162 SER 162 162 162 SER SER B . n 
B 1 163 TYR 163 163 163 TYR TYR B . n 
B 1 164 PRO 164 164 164 PRO PRO B . n 
B 1 165 LEU 165 165 165 LEU LEU B . n 
B 1 166 LEU 166 166 166 LEU LEU B . n 
B 1 167 ASN 167 167 167 ASN ASN B . n 
B 1 168 VAL 168 168 168 VAL VAL B . n 
B 1 169 THR 169 169 169 THR THR B . n 
B 1 170 MET 170 170 170 MET MET B . n 
B 1 171 PRO 171 171 171 PRO PRO B . n 
B 1 172 ASN 172 172 172 ASN ASN B . n 
B 1 173 ASN 173 173 173 ASN ASN B . n 
B 1 174 TYR 174 174 174 TYR TYR B . n 
B 1 175 ASN 175 175 175 ASN ASN B . n 
B 1 176 PHE 176 176 176 PHE PHE B . n 
B 1 177 ASP 177 177 177 ASP ASP B . n 
B 1 178 LYS 178 178 178 LYS LYS B . n 
B 1 179 LEU 179 179 179 LEU LEU B . n 
B 1 180 TYR 180 180 180 TYR TYR B . n 
B 1 181 ILE 181 181 181 ILE ILE B . n 
B 1 182 TRP 182 182 182 TRP TRP B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 HIS 185 185 185 HIS HIS B . n 
B 1 186 HIS 186 186 186 HIS HIS B . n 
B 1 187 PRO 187 187 187 PRO PRO B . n 
B 1 188 SER 188 188 188 SER SER B . n 
B 1 189 THR 189 189 189 THR THR B . n 
B 1 190 ASN 190 190 190 ASN ASN B . n 
B 1 191 GLN 191 191 191 GLN GLN B . n 
B 1 192 GLU 192 192 192 GLU GLU B . n 
B 1 193 GLN 193 193 193 GLN GLN B . n 
B 1 194 THR 194 194 194 THR THR B . n 
B 1 195 ASN 195 195 195 ASN ASN B . n 
B 1 196 LEU 196 196 196 LEU LEU B . n 
B 1 197 TYR 197 197 197 TYR TYR B . n 
B 1 198 VAL 198 198 198 VAL VAL B . n 
B 1 199 GLN 199 199 199 GLN GLN B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 SER 201 201 201 SER SER B . n 
B 1 202 GLY 202 202 202 GLY GLY B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 THR 205 205 205 THR THR B . n 
B 1 206 VAL 206 206 206 VAL VAL B . n 
B 1 207 SER 207 207 207 SER SER B . n 
B 1 208 THR 208 208 208 THR THR B . n 
B 1 209 ARG 209 209 209 ARG ARG B . n 
B 1 210 ARG 210 210 210 ARG ARG B . n 
B 1 211 SER 211 211 211 SER SER B . n 
B 1 212 GLN 212 212 212 GLN GLN B . n 
B 1 213 GLN 213 213 213 GLN GLN B . n 
B 1 214 THR 214 214 214 THR THR B . n 
B 1 215 ILE 215 215 215 ILE ILE B . n 
B 1 216 VAL 216 216 216 VAL VAL B . n 
B 1 217 PRO 217 217 217 PRO PRO B . n 
B 1 218 ASN 218 218 218 ASN ASN B . n 
B 1 219 ILE 219 219 219 ILE ILE B . n 
B 1 220 GLY 220 220 220 GLY GLY B . n 
B 1 221 SER 221 221 221 SER SER B . n 
B 1 222 ARG 222 222 222 ARG ARG B . n 
B 1 223 PRO 223 223 223 PRO PRO B . n 
B 1 224 TRP 224 224 224 TRP TRP B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 ARG 226 226 226 ARG ARG B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 GLN 228 228 228 GLN GLN B . n 
B 1 229 SER 229 229 229 SER SER B . n 
B 1 230 GLY 230 230 230 GLY GLY B . n 
B 1 231 ARG 231 231 231 ARG ARG B . n 
B 1 232 ILE 232 232 232 ILE ILE B . n 
B 1 233 SER 233 233 233 SER SER B . n 
B 1 234 ILE 234 234 234 ILE ILE B . n 
B 1 235 TYR 235 235 235 TYR TYR B . n 
B 1 236 TRP 236 236 236 TRP TRP B . n 
B 1 237 THR 237 237 237 THR THR B . n 
B 1 238 ILE 238 238 238 ILE ILE B . n 
B 1 239 VAL 239 239 239 VAL VAL B . n 
B 1 240 LYS 240 240 240 LYS LYS B . n 
B 1 241 PRO 241 241 241 PRO PRO B . n 
B 1 242 GLY 242 242 242 GLY GLY B . n 
B 1 243 ASP 243 243 243 ASP ASP B . n 
B 1 244 VAL 244 244 244 VAL VAL B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 ILE 247 247 247 ILE ILE B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 SER 249 249 249 SER SER B . n 
B 1 250 ASN 250 250 250 ASN ASN B . n 
B 1 251 GLY 251 251 251 GLY GLY B . n 
B 1 252 ASN 252 252 252 ASN ASN B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ILE 254 254 254 ILE ILE B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 PRO 256 256 256 PRO PRO B . n 
B 1 257 ARG 257 257 257 ARG ARG B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 PHE 259 259 259 PHE PHE B . n 
B 1 260 PHE 260 260 260 PHE PHE B . n 
B 1 261 LYS 261 261 261 LYS LYS B . n 
B 1 262 ILE 262 262 262 ILE ILE B . n 
B 1 263 ARG 263 263 263 ARG ARG B . n 
B 1 264 THR 264 264 264 THR THR B . n 
B 1 265 GLY 265 265 265 GLY GLY B . n 
B 1 266 ARG 266 266 266 ARG ARG B . n 
B 1 267 SER 267 267 267 SER SER B . n 
B 1 268 SER 268 268 268 SER SER B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 MET 270 270 270 MET MET B . n 
B 1 271 ARG 271 271 271 ARG ARG B . n 
B 1 272 SER 272 272 272 SER SER B . n 
B 1 273 ASP 273 273 273 ASP ASP B . n 
B 1 274 ALA 274 274 274 ALA ALA B . n 
B 1 275 PRO 275 275 275 PRO PRO B . n 
B 1 276 ILE 276 276 276 ILE ILE B . n 
B 1 277 GLU 277 277 277 GLU GLU B . n 
B 1 278 THR 278 278 278 THR THR B . n 
B 1 279 CYS 279 279 279 CYS CYS B . n 
B 1 280 ILE 280 280 280 ILE ILE B . n 
B 1 281 SER 281 281 281 SER SER B . n 
B 1 282 GLU 282 282 282 GLU GLU B . n 
B 1 283 CYS 283 283 283 CYS CYS B . n 
B 1 284 ILE 284 284 284 ILE ILE B . n 
B 1 285 THR 285 285 285 THR THR B . n 
B 1 286 PRO 286 286 286 PRO PRO B . n 
B 1 287 ASN 287 287 287 ASN ASN B . n 
B 1 288 GLY 288 288 288 GLY GLY B . n 
B 1 289 SER 289 289 289 SER SER B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 PRO 291 291 291 PRO PRO B . n 
B 1 292 ASN 292 292 292 ASN ASN B . n 
B 1 293 ASP 293 293 293 ASP ASP B . n 
B 1 294 LYS 294 294 294 LYS LYS B . n 
B 1 295 PRO 295 295 295 PRO PRO B . n 
B 1 296 PHE 296 296 296 PHE PHE B . n 
B 1 297 GLN 297 297 297 GLN GLN B . n 
B 1 298 ASN 298 298 298 ASN ASN B . n 
B 1 299 VAL 299 299 299 VAL VAL B . n 
B 1 300 ASN 300 300 300 ASN ASN B . n 
B 1 301 LYS 301 301 301 LYS LYS B . n 
B 1 302 ILE 302 302 302 ILE ILE B . n 
B 1 303 THR 303 303 303 THR THR B . n 
B 1 304 TYR 304 304 304 TYR TYR B . n 
B 1 305 GLY 305 305 305 GLY GLY B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 CYS 307 307 307 CYS CYS B . n 
B 1 308 PRO 308 308 308 PRO PRO B . n 
B 1 309 LYS 309 309 309 LYS LYS B . n 
B 1 310 TYR 310 310 310 TYR TYR B . n 
B 1 311 VAL 311 311 311 VAL VAL B . n 
B 1 312 LYS 312 312 312 LYS LYS B . n 
B 1 313 GLN 313 313 313 GLN GLN B . n 
B 1 314 ASN 314 314 314 ASN ASN B . n 
B 1 315 THR 315 315 315 THR THR B . n 
B 1 316 LEU 316 316 316 LEU LEU B . n 
B 1 317 LYS 317 317 317 LYS LYS B . n 
B 1 318 LEU 318 318 318 LEU LEU B . n 
B 1 319 ALA 319 319 319 ALA ALA B . n 
B 1 320 THR 320 320 320 THR THR B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 MET 322 322 322 MET MET B . n 
B 1 323 ARG 323 323 323 ARG ARG B . n 
B 1 324 ASN 324 324 324 ASN ASN B . n 
B 1 325 VAL 325 325 325 VAL VAL B . n 
B 1 326 PRO 326 326 326 PRO PRO B . n 
B 1 327 GLU 327 327 327 GLU GLU B . n 
B 1 328 LYS 328 328 328 LYS LYS B . n 
B 1 329 GLN 329 329 ?   ?   ?   B . n 
B 1 330 THR 330 330 ?   ?   ?   B . n 
B 1 331 ARG 331 331 ?   ?   ?   B . n 
B 1 332 GLY 332 332 ?   ?   ?   B . n 
B 1 333 LEU 333 333 ?   ?   ?   B . n 
B 1 334 PHE 334 334 ?   ?   ?   B . n 
B 1 335 GLY 335 335 ?   ?   ?   B . n 
B 1 336 ALA 336 336 336 ALA ALA B . n 
B 1 337 ILE 337 337 337 ILE ILE B . n 
B 1 338 ALA 338 338 338 ALA ALA B . n 
B 1 339 GLY 339 339 339 GLY GLY B . n 
B 1 340 PHE 340 340 340 PHE PHE B . n 
B 1 341 ILE 341 341 341 ILE ILE B . n 
B 1 342 GLU 342 342 342 GLU GLU B . n 
B 1 343 ASN 343 343 343 ASN ASN B . n 
B 1 344 GLY 344 344 344 GLY GLY B . n 
B 1 345 TRP 345 345 345 TRP TRP B . n 
B 1 346 GLU 346 346 346 GLU GLU B . n 
B 1 347 GLY 347 347 347 GLY GLY B . n 
B 1 348 MET 348 348 348 MET MET B . n 
B 1 349 ILE 349 349 349 ILE ILE B . n 
B 1 350 ASP 350 350 350 ASP ASP B . n 
B 1 351 GLY 351 351 351 GLY GLY B . n 
B 1 352 TRP 352 352 352 TRP TRP B . n 
B 1 353 TYR 353 353 353 TYR TYR B . n 
B 1 354 GLY 354 354 354 GLY GLY B . n 
B 1 355 PHE 355 355 355 PHE PHE B . n 
B 1 356 ARG 356 356 356 ARG ARG B . n 
B 1 357 HIS 357 357 357 HIS HIS B . n 
B 1 358 GLN 358 358 358 GLN GLN B . n 
B 1 359 ASN 359 359 359 ASN ASN B . n 
B 1 360 SER 360 360 360 SER SER B . n 
B 1 361 GLU 361 361 361 GLU GLU B . n 
B 1 362 GLY 362 362 362 GLY GLY B . n 
B 1 363 THR 363 363 363 THR THR B . n 
B 1 364 GLY 364 364 364 GLY GLY B . n 
B 1 365 GLN 365 365 365 GLN GLN B . n 
B 1 366 ALA 366 366 366 ALA ALA B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 ASP 368 368 368 ASP ASP B . n 
B 1 369 LEU 369 369 369 LEU LEU B . n 
B 1 370 LYS 370 370 370 LYS LYS B . n 
B 1 371 SER 371 371 371 SER SER B . n 
B 1 372 THR 372 372 372 THR THR B . n 
B 1 373 GLN 373 373 373 GLN GLN B . n 
B 1 374 ALA 374 374 374 ALA ALA B . n 
B 1 375 ALA 375 375 375 ALA ALA B . n 
B 1 376 ILE 376 376 376 ILE ILE B . n 
B 1 377 ASP 377 377 377 ASP ASP B . n 
B 1 378 GLN 378 378 378 GLN GLN B . n 
B 1 379 ILE 379 379 379 ILE ILE B . n 
B 1 380 ASN 380 380 380 ASN ASN B . n 
B 1 381 GLY 381 381 381 GLY GLY B . n 
B 1 382 LYS 382 382 382 LYS LYS B . n 
B 1 383 LEU 383 383 383 LEU LEU B . n 
B 1 384 ASN 384 384 384 ASN ASN B . n 
B 1 385 ARG 385 385 385 ARG ARG B . n 
B 1 386 VAL 386 386 386 VAL VAL B . n 
B 1 387 ILE 387 387 387 ILE ILE B . n 
B 1 388 GLU 388 388 388 GLU GLU B . n 
B 1 389 LYS 389 389 389 LYS LYS B . n 
B 1 390 THR 390 390 390 THR THR B . n 
B 1 391 ASN 391 391 391 ASN ASN B . n 
B 1 392 GLU 392 392 392 GLU GLU B . n 
B 1 393 LYS 393 393 393 LYS LYS B . n 
B 1 394 PHE 394 394 394 PHE PHE B . n 
B 1 395 HIS 395 395 395 HIS HIS B . n 
B 1 396 GLN 396 396 396 GLN GLN B . n 
B 1 397 ILE 397 397 397 ILE ILE B . n 
B 1 398 GLU 398 398 398 GLU GLU B . n 
B 1 399 LYS 399 399 399 LYS LYS B . n 
B 1 400 GLU 400 400 400 GLU GLU B . n 
B 1 401 PHE 401 401 401 PHE PHE B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 GLU 403 403 403 GLU GLU B . n 
B 1 404 VAL 404 404 404 VAL VAL B . n 
B 1 405 GLU 405 405 405 GLU GLU B . n 
B 1 406 GLY 406 406 406 GLY GLY B . n 
B 1 407 ARG 407 407 407 ARG ARG B . n 
B 1 408 ILE 408 408 408 ILE ILE B . n 
B 1 409 GLN 409 409 409 GLN GLN B . n 
B 1 410 ASP 410 410 410 ASP ASP B . n 
B 1 411 LEU 411 411 411 LEU LEU B . n 
B 1 412 GLU 412 412 412 GLU GLU B . n 
B 1 413 LYS 413 413 413 LYS LYS B . n 
B 1 414 TYR 414 414 414 TYR TYR B . n 
B 1 415 VAL 415 415 415 VAL VAL B . n 
B 1 416 GLU 416 416 416 GLU GLU B . n 
B 1 417 ASP 417 417 417 ASP ASP B . n 
B 1 418 THR 418 418 418 THR THR B . n 
B 1 419 LYS 419 419 419 LYS LYS B . n 
B 1 420 VAL 420 420 420 VAL VAL B . n 
B 1 421 ASP 421 421 421 ASP ASP B . n 
B 1 422 LEU 422 422 422 LEU LEU B . n 
B 1 423 TRP 423 423 423 TRP TRP B . n 
B 1 424 SER 424 424 424 SER SER B . n 
B 1 425 TYR 425 425 425 TYR TYR B . n 
B 1 426 ASN 426 426 426 ASN ASN B . n 
B 1 427 ALA 427 427 427 ALA ALA B . n 
B 1 428 GLU 428 428 428 GLU GLU B . n 
B 1 429 LEU 429 429 429 LEU LEU B . n 
B 1 430 LEU 430 430 430 LEU LEU B . n 
B 1 431 VAL 431 431 431 VAL VAL B . n 
B 1 432 ALA 432 432 432 ALA ALA B . n 
B 1 433 LEU 433 433 433 LEU LEU B . n 
B 1 434 GLU 434 434 434 GLU GLU B . n 
B 1 435 ASN 435 435 435 ASN ASN B . n 
B 1 436 GLN 436 436 436 GLN GLN B . n 
B 1 437 HIS 437 437 437 HIS HIS B . n 
B 1 438 THR 438 438 438 THR THR B . n 
B 1 439 ILE 439 439 439 ILE ILE B . n 
B 1 440 ASP 440 440 440 ASP ASP B . n 
B 1 441 LEU 441 441 441 LEU LEU B . n 
B 1 442 THR 442 442 442 THR THR B . n 
B 1 443 ASP 443 443 443 ASP ASP B . n 
B 1 444 SER 444 444 444 SER SER B . n 
B 1 445 GLU 445 445 445 GLU GLU B . n 
B 1 446 MET 446 446 446 MET MET B . n 
B 1 447 ASN 447 447 447 ASN ASN B . n 
B 1 448 LYS 448 448 448 LYS LYS B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 PHE 450 450 450 PHE PHE B . n 
B 1 451 GLU 451 451 451 GLU GLU B . n 
B 1 452 LYS 452 452 452 LYS LYS B . n 
B 1 453 THR 453 453 453 THR THR B . n 
B 1 454 ARG 454 454 454 ARG ARG B . n 
B 1 455 ARG 455 455 455 ARG ARG B . n 
B 1 456 GLN 456 456 456 GLN GLN B . n 
B 1 457 LEU 457 457 457 LEU LEU B . n 
B 1 458 ARG 458 458 458 ARG ARG B . n 
B 1 459 GLU 459 459 459 GLU GLU B . n 
B 1 460 ASN 460 460 460 ASN ASN B . n 
B 1 461 ALA 461 461 461 ALA ALA B . n 
B 1 462 GLU 462 462 462 GLU GLU B . n 
B 1 463 ASP 463 463 463 ASP ASP B . n 
B 1 464 MET 464 464 464 MET MET B . n 
B 1 465 GLY 465 465 465 GLY GLY B . n 
B 1 466 ASN 466 466 466 ASN ASN B . n 
B 1 467 GLY 467 467 467 GLY GLY B . n 
B 1 468 CYS 468 468 468 CYS CYS B . n 
B 1 469 PHE 469 469 469 PHE PHE B . n 
B 1 470 LYS 470 470 470 LYS LYS B . n 
B 1 471 ILE 471 471 471 ILE ILE B . n 
B 1 472 TYR 472 472 472 TYR TYR B . n 
B 1 473 HIS 473 473 473 HIS HIS B . n 
B 1 474 LYS 474 474 474 LYS LYS B . n 
B 1 475 CYS 475 475 475 CYS CYS B . n 
B 1 476 ASP 476 476 476 ASP ASP B . n 
B 1 477 ASN 477 477 477 ASN ASN B . n 
B 1 478 ALA 478 478 478 ALA ALA B . n 
B 1 479 CYS 479 479 479 CYS CYS B . n 
B 1 480 ILE 480 480 480 ILE ILE B . n 
B 1 481 GLU 481 481 481 GLU GLU B . n 
B 1 482 SER 482 482 482 SER SER B . n 
B 1 483 ILE 483 483 483 ILE ILE B . n 
B 1 484 ARG 484 484 484 ARG ARG B . n 
B 1 485 ASN 485 485 485 ASN ASN B . n 
B 1 486 GLY 486 486 486 GLY GLY B . n 
B 1 487 THR 487 487 487 THR THR B . n 
B 1 488 TYR 488 488 488 TYR TYR B . n 
B 1 489 ASP 489 489 489 ASP ASP B . n 
B 1 490 HIS 490 490 490 HIS HIS B . n 
B 1 491 ASP 491 491 491 ASP ASP B . n 
B 1 492 ILE 492 492 492 ILE ILE B . n 
B 1 493 TYR 493 493 493 TYR TYR B . n 
B 1 494 ARG 494 494 494 ARG ARG B . n 
B 1 495 ASP 495 495 495 ASP ASP B . n 
B 1 496 GLU 496 496 496 GLU GLU B . n 
B 1 497 ALA 497 497 497 ALA ALA B . n 
B 1 498 LEU 498 498 498 LEU LEU B . n 
B 1 499 ASN 499 499 499 ASN ASN B . n 
B 1 500 ASN 500 500 500 ASN ASN B . n 
B 1 501 ARG 501 501 501 ARG ARG B . n 
B 1 502 PHE 502 502 502 PHE PHE B . n 
B 1 503 GLN 503 503 ?   ?   ?   B . n 
B 1 504 ILE 504 504 ?   ?   ?   B . n 
B 1 505 ARG 505 505 ?   ?   ?   B . n 
B 1 506 GLY 506 506 ?   ?   ?   B . n 
B 1 507 VAL 507 507 ?   ?   ?   B . n 
B 1 508 GLU 508 508 ?   ?   ?   B . n 
B 1 509 PHE 509 509 ?   ?   ?   B . n 
C 1 1   LEU 1   1   ?   ?   ?   C . n 
C 1 2   GLN 2   2   ?   ?   ?   C . n 
C 1 3   GLN 3   3   ?   ?   ?   C . n 
C 1 4   ASN 4   4   ?   ?   ?   C . n 
C 1 5   LEU 5   5   ?   ?   ?   C . n 
C 1 6   PRO 6   6   ?   ?   ?   C . n 
C 1 7   GLY 7   7   ?   ?   ?   C . n 
C 1 8   LYS 8   8   ?   ?   ?   C . n 
C 1 9   ASP 9   9   ?   ?   ?   C . n 
C 1 10  SER 10  10  ?   ?   ?   C . n 
C 1 11  SER 11  11  ?   ?   ?   C . n 
C 1 12  THR 12  12  12  THR THR C . n 
C 1 13  ALA 13  13  13  ALA ALA C . n 
C 1 14  THR 14  14  14  THR THR C . n 
C 1 15  LEU 15  15  15  LEU LEU C . n 
C 1 16  CYS 16  16  16  CYS CYS C . n 
C 1 17  LEU 17  17  17  LEU LEU C . n 
C 1 18  GLY 18  18  18  GLY GLY C . n 
C 1 19  HIS 19  19  19  HIS HIS C . n 
C 1 20  HIS 20  20  20  HIS HIS C . n 
C 1 21  SER 21  21  21  SER SER C . n 
C 1 22  VAL 22  22  22  VAL VAL C . n 
C 1 23  PRO 23  23  23  PRO PRO C . n 
C 1 24  ASN 24  24  24  ASN ASN C . n 
C 1 25  GLY 25  25  25  GLY GLY C . n 
C 1 26  THR 26  26  26  THR THR C . n 
C 1 27  ILE 27  27  27  ILE ILE C . n 
C 1 28  VAL 28  28  28  VAL VAL C . n 
C 1 29  LYS 29  29  29  LYS LYS C . n 
C 1 30  THR 30  30  30  THR THR C . n 
C 1 31  ILE 31  31  31  ILE ILE C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  ASP 33  33  33  ASP ASP C . n 
C 1 34  ASP 34  34  34  ASP ASP C . n 
C 1 35  GLN 35  35  35  GLN GLN C . n 
C 1 36  ILE 36  36  36  ILE ILE C . n 
C 1 37  GLU 37  37  37  GLU GLU C . n 
C 1 38  VAL 38  38  38  VAL VAL C . n 
C 1 39  THR 39  39  39  THR THR C . n 
C 1 40  ASN 40  40  40  ASN ASN C . n 
C 1 41  ALA 41  41  41  ALA ALA C . n 
C 1 42  THR 42  42  42  THR THR C . n 
C 1 43  GLU 43  43  43  GLU GLU C . n 
C 1 44  LEU 44  44  44  LEU LEU C . n 
C 1 45  VAL 45  45  45  VAL VAL C . n 
C 1 46  GLN 46  46  46  GLN GLN C . n 
C 1 47  ASN 47  47  47  ASN ASN C . n 
C 1 48  SER 48  48  48  SER SER C . n 
C 1 49  SER 49  49  49  SER SER C . n 
C 1 50  THR 50  50  50  THR THR C . n 
C 1 51  GLY 51  51  51  GLY GLY C . n 
C 1 52  LYS 52  52  52  LYS LYS C . n 
C 1 53  ILE 53  53  53  ILE ILE C . n 
C 1 54  CYS 54  54  54  CYS CYS C . n 
C 1 55  ASN 55  55  55  ASN ASN C . n 
C 1 56  ASN 56  56  56  ASN ASN C . n 
C 1 57  PRO 57  57  57  PRO PRO C . n 
C 1 58  HIS 58  58  58  HIS HIS C . n 
C 1 59  LYS 59  59  59  LYS LYS C . n 
C 1 60  VAL 60  60  60  VAL VAL C . n 
C 1 61  LEU 61  61  61  LEU LEU C . n 
C 1 62  ASP 62  62  62  ASP ASP C . n 
C 1 63  GLY 63  63  63  GLY GLY C . n 
C 1 64  ARG 64  64  64  ARG ARG C . n 
C 1 65  ASP 65  65  65  ASP ASP C . n 
C 1 66  CYS 66  66  66  CYS CYS C . n 
C 1 67  THR 67  67  67  THR THR C . n 
C 1 68  LEU 68  68  68  LEU LEU C . n 
C 1 69  ILE 69  69  69  ILE ILE C . n 
C 1 70  ASP 70  70  70  ASP ASP C . n 
C 1 71  ALA 71  71  71  ALA ALA C . n 
C 1 72  MET 72  72  72  MET MET C . n 
C 1 73  LEU 73  73  73  LEU LEU C . n 
C 1 74  GLY 74  74  74  GLY GLY C . n 
C 1 75  ASP 75  75  75  ASP ASP C . n 
C 1 76  PRO 76  76  76  PRO PRO C . n 
C 1 77  HIS 77  77  77  HIS HIS C . n 
C 1 78  CYS 78  78  78  CYS CYS C . n 
C 1 79  ASP 79  79  79  ASP ASP C . n 
C 1 80  VAL 80  80  80  VAL VAL C . n 
C 1 81  PHE 81  81  81  PHE PHE C . n 
C 1 82  GLN 82  82  82  GLN GLN C . n 
C 1 83  ASP 83  83  83  ASP ASP C . n 
C 1 84  GLU 84  84  84  GLU GLU C . n 
C 1 85  LYS 85  85  85  LYS LYS C . n 
C 1 86  TRP 86  86  86  TRP TRP C . n 
C 1 87  ASP 87  87  87  ASP ASP C . n 
C 1 88  LEU 88  88  88  LEU LEU C . n 
C 1 89  PHE 89  89  89  PHE PHE C . n 
C 1 90  VAL 90  90  90  VAL VAL C . n 
C 1 91  GLU 91  91  91  GLU GLU C . n 
C 1 92  ARG 92  92  92  ARG ARG C . n 
C 1 93  SER 93  93  93  SER SER C . n 
C 1 94  SER 94  94  94  SER SER C . n 
C 1 95  ALA 95  95  95  ALA ALA C . n 
C 1 96  PHE 96  96  96  PHE PHE C . n 
C 1 97  SER 97  97  97  SER SER C . n 
C 1 98  ASN 98  98  98  ASN ASN C . n 
C 1 99  CYS 99  99  99  CYS CYS C . n 
C 1 100 TYR 100 100 100 TYR TYR C . n 
C 1 101 PRO 101 101 101 PRO PRO C . n 
C 1 102 TYR 102 102 102 TYR TYR C . n 
C 1 103 ASP 103 103 103 ASP ASP C . n 
C 1 104 VAL 104 104 104 VAL VAL C . n 
C 1 105 PRO 105 105 105 PRO PRO C . n 
C 1 106 ASP 106 106 106 ASP ASP C . n 
C 1 107 TYR 107 107 107 TYR TYR C . n 
C 1 108 ALA 108 108 108 ALA ALA C . n 
C 1 109 SER 109 109 109 SER SER C . n 
C 1 110 LEU 110 110 110 LEU LEU C . n 
C 1 111 ARG 111 111 111 ARG ARG C . n 
C 1 112 SER 112 112 112 SER SER C . n 
C 1 113 LEU 113 113 113 LEU LEU C . n 
C 1 114 ILE 114 114 114 ILE ILE C . n 
C 1 115 ALA 115 115 115 ALA ALA C . n 
C 1 116 SER 116 116 116 SER SER C . n 
C 1 117 SER 117 117 117 SER SER C . n 
C 1 118 GLY 118 118 118 GLY GLY C . n 
C 1 119 THR 119 119 119 THR THR C . n 
C 1 120 LEU 120 120 120 LEU LEU C . n 
C 1 121 ASP 121 121 121 ASP ASP C . n 
C 1 122 PHE 122 122 122 PHE PHE C . n 
C 1 123 ILE 123 123 123 ILE ILE C . n 
C 1 124 THR 124 124 124 THR THR C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 SER 126 126 126 SER SER C . n 
C 1 127 PHE 127 127 127 PHE PHE C . n 
C 1 128 THR 128 128 128 THR THR C . n 
C 1 129 TRP 129 129 129 TRP TRP C . n 
C 1 130 ALA 130 130 130 ALA ALA C . n 
C 1 131 GLY 131 131 131 GLY GLY C . n 
C 1 132 VAL 132 132 132 VAL VAL C . n 
C 1 133 SER 133 133 133 SER SER C . n 
C 1 134 GLN 134 134 134 GLN GLN C . n 
C 1 135 ASN 135 135 135 ASN ASN C . n 
C 1 136 GLY 136 136 136 GLY GLY C . n 
C 1 137 GLY 137 137 137 GLY GLY C . n 
C 1 138 SER 138 138 138 SER SER C . n 
C 1 139 SER 139 139 139 SER SER C . n 
C 1 140 ALA 140 140 140 ALA ALA C . n 
C 1 141 CYS 141 141 141 CYS CYS C . n 
C 1 142 LYS 142 142 142 LYS LYS C . n 
C 1 143 ARG 143 143 143 ARG ARG C . n 
C 1 144 GLY 144 144 144 GLY GLY C . n 
C 1 145 PRO 145 145 145 PRO PRO C . n 
C 1 146 ALA 146 146 146 ALA ALA C . n 
C 1 147 ASN 147 147 147 ASN ASN C . n 
C 1 148 GLY 148 148 148 GLY GLY C . n 
C 1 149 PHE 149 149 149 PHE PHE C . n 
C 1 150 PHE 150 150 150 PHE PHE C . n 
C 1 151 SER 151 151 151 SER SER C . n 
C 1 152 ARG 152 152 152 ARG ARG C . n 
C 1 153 LEU 153 153 153 LEU LEU C . n 
C 1 154 ASN 154 154 154 ASN ASN C . n 
C 1 155 TRP 155 155 155 TRP TRP C . n 
C 1 156 LEU 156 156 156 LEU LEU C . n 
C 1 157 THR 157 157 157 THR THR C . n 
C 1 158 LYS 158 158 158 LYS LYS C . n 
C 1 159 SER 159 159 159 SER SER C . n 
C 1 160 GLY 160 160 160 GLY GLY C . n 
C 1 161 SER 161 161 161 SER SER C . n 
C 1 162 SER 162 162 162 SER SER C . n 
C 1 163 TYR 163 163 163 TYR TYR C . n 
C 1 164 PRO 164 164 164 PRO PRO C . n 
C 1 165 LEU 165 165 165 LEU LEU C . n 
C 1 166 LEU 166 166 166 LEU LEU C . n 
C 1 167 ASN 167 167 167 ASN ASN C . n 
C 1 168 VAL 168 168 168 VAL VAL C . n 
C 1 169 THR 169 169 169 THR THR C . n 
C 1 170 MET 170 170 170 MET MET C . n 
C 1 171 PRO 171 171 171 PRO PRO C . n 
C 1 172 ASN 172 172 172 ASN ASN C . n 
C 1 173 ASN 173 173 173 ASN ASN C . n 
C 1 174 TYR 174 174 174 TYR TYR C . n 
C 1 175 ASN 175 175 175 ASN ASN C . n 
C 1 176 PHE 176 176 176 PHE PHE C . n 
C 1 177 ASP 177 177 177 ASP ASP C . n 
C 1 178 LYS 178 178 178 LYS LYS C . n 
C 1 179 LEU 179 179 179 LEU LEU C . n 
C 1 180 TYR 180 180 180 TYR TYR C . n 
C 1 181 ILE 181 181 181 ILE ILE C . n 
C 1 182 TRP 182 182 182 TRP TRP C . n 
C 1 183 GLY 183 183 183 GLY GLY C . n 
C 1 184 VAL 184 184 184 VAL VAL C . n 
C 1 185 HIS 185 185 185 HIS HIS C . n 
C 1 186 HIS 186 186 186 HIS HIS C . n 
C 1 187 PRO 187 187 187 PRO PRO C . n 
C 1 188 SER 188 188 188 SER SER C . n 
C 1 189 THR 189 189 189 THR THR C . n 
C 1 190 ASN 190 190 190 ASN ASN C . n 
C 1 191 GLN 191 191 191 GLN GLN C . n 
C 1 192 GLU 192 192 192 GLU GLU C . n 
C 1 193 GLN 193 193 193 GLN GLN C . n 
C 1 194 THR 194 194 194 THR THR C . n 
C 1 195 ASN 195 195 195 ASN ASN C . n 
C 1 196 LEU 196 196 196 LEU LEU C . n 
C 1 197 TYR 197 197 197 TYR TYR C . n 
C 1 198 VAL 198 198 198 VAL VAL C . n 
C 1 199 GLN 199 199 199 GLN GLN C . n 
C 1 200 ALA 200 200 200 ALA ALA C . n 
C 1 201 SER 201 201 201 SER SER C . n 
C 1 202 GLY 202 202 202 GLY GLY C . n 
C 1 203 ARG 203 203 203 ARG ARG C . n 
C 1 204 VAL 204 204 204 VAL VAL C . n 
C 1 205 THR 205 205 205 THR THR C . n 
C 1 206 VAL 206 206 206 VAL VAL C . n 
C 1 207 SER 207 207 207 SER SER C . n 
C 1 208 THR 208 208 208 THR THR C . n 
C 1 209 ARG 209 209 209 ARG ARG C . n 
C 1 210 ARG 210 210 210 ARG ARG C . n 
C 1 211 SER 211 211 211 SER SER C . n 
C 1 212 GLN 212 212 212 GLN GLN C . n 
C 1 213 GLN 213 213 213 GLN GLN C . n 
C 1 214 THR 214 214 214 THR THR C . n 
C 1 215 ILE 215 215 215 ILE ILE C . n 
C 1 216 VAL 216 216 216 VAL VAL C . n 
C 1 217 PRO 217 217 217 PRO PRO C . n 
C 1 218 ASN 218 218 218 ASN ASN C . n 
C 1 219 ILE 219 219 219 ILE ILE C . n 
C 1 220 GLY 220 220 220 GLY GLY C . n 
C 1 221 SER 221 221 221 SER SER C . n 
C 1 222 ARG 222 222 222 ARG ARG C . n 
C 1 223 PRO 223 223 223 PRO PRO C . n 
C 1 224 TRP 224 224 224 TRP TRP C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 ARG 226 226 226 ARG ARG C . n 
C 1 227 GLY 227 227 227 GLY GLY C . n 
C 1 228 GLN 228 228 228 GLN GLN C . n 
C 1 229 SER 229 229 229 SER SER C . n 
C 1 230 GLY 230 230 230 GLY GLY C . n 
C 1 231 ARG 231 231 231 ARG ARG C . n 
C 1 232 ILE 232 232 232 ILE ILE C . n 
C 1 233 SER 233 233 233 SER SER C . n 
C 1 234 ILE 234 234 234 ILE ILE C . n 
C 1 235 TYR 235 235 235 TYR TYR C . n 
C 1 236 TRP 236 236 236 TRP TRP C . n 
C 1 237 THR 237 237 237 THR THR C . n 
C 1 238 ILE 238 238 238 ILE ILE C . n 
C 1 239 VAL 239 239 239 VAL VAL C . n 
C 1 240 LYS 240 240 240 LYS LYS C . n 
C 1 241 PRO 241 241 241 PRO PRO C . n 
C 1 242 GLY 242 242 242 GLY GLY C . n 
C 1 243 ASP 243 243 243 ASP ASP C . n 
C 1 244 VAL 244 244 244 VAL VAL C . n 
C 1 245 LEU 245 245 245 LEU LEU C . n 
C 1 246 VAL 246 246 246 VAL VAL C . n 
C 1 247 ILE 247 247 247 ILE ILE C . n 
C 1 248 ASN 248 248 248 ASN ASN C . n 
C 1 249 SER 249 249 249 SER SER C . n 
C 1 250 ASN 250 250 250 ASN ASN C . n 
C 1 251 GLY 251 251 251 GLY GLY C . n 
C 1 252 ASN 252 252 252 ASN ASN C . n 
C 1 253 LEU 253 253 253 LEU LEU C . n 
C 1 254 ILE 254 254 254 ILE ILE C . n 
C 1 255 ALA 255 255 255 ALA ALA C . n 
C 1 256 PRO 256 256 256 PRO PRO C . n 
C 1 257 ARG 257 257 257 ARG ARG C . n 
C 1 258 GLY 258 258 258 GLY GLY C . n 
C 1 259 PHE 259 259 259 PHE PHE C . n 
C 1 260 PHE 260 260 260 PHE PHE C . n 
C 1 261 LYS 261 261 261 LYS LYS C . n 
C 1 262 ILE 262 262 262 ILE ILE C . n 
C 1 263 ARG 263 263 263 ARG ARG C . n 
C 1 264 THR 264 264 264 THR THR C . n 
C 1 265 GLY 265 265 265 GLY GLY C . n 
C 1 266 ARG 266 266 266 ARG ARG C . n 
C 1 267 SER 267 267 267 SER SER C . n 
C 1 268 SER 268 268 268 SER SER C . n 
C 1 269 ILE 269 269 269 ILE ILE C . n 
C 1 270 MET 270 270 270 MET MET C . n 
C 1 271 ARG 271 271 271 ARG ARG C . n 
C 1 272 SER 272 272 272 SER SER C . n 
C 1 273 ASP 273 273 273 ASP ASP C . n 
C 1 274 ALA 274 274 274 ALA ALA C . n 
C 1 275 PRO 275 275 275 PRO PRO C . n 
C 1 276 ILE 276 276 276 ILE ILE C . n 
C 1 277 GLU 277 277 277 GLU GLU C . n 
C 1 278 THR 278 278 278 THR THR C . n 
C 1 279 CYS 279 279 279 CYS CYS C . n 
C 1 280 ILE 280 280 280 ILE ILE C . n 
C 1 281 SER 281 281 281 SER SER C . n 
C 1 282 GLU 282 282 282 GLU GLU C . n 
C 1 283 CYS 283 283 283 CYS CYS C . n 
C 1 284 ILE 284 284 284 ILE ILE C . n 
C 1 285 THR 285 285 285 THR THR C . n 
C 1 286 PRO 286 286 286 PRO PRO C . n 
C 1 287 ASN 287 287 287 ASN ASN C . n 
C 1 288 GLY 288 288 288 GLY GLY C . n 
C 1 289 SER 289 289 289 SER SER C . n 
C 1 290 ILE 290 290 290 ILE ILE C . n 
C 1 291 PRO 291 291 291 PRO PRO C . n 
C 1 292 ASN 292 292 292 ASN ASN C . n 
C 1 293 ASP 293 293 293 ASP ASP C . n 
C 1 294 LYS 294 294 294 LYS LYS C . n 
C 1 295 PRO 295 295 295 PRO PRO C . n 
C 1 296 PHE 296 296 296 PHE PHE C . n 
C 1 297 GLN 297 297 297 GLN GLN C . n 
C 1 298 ASN 298 298 298 ASN ASN C . n 
C 1 299 VAL 299 299 299 VAL VAL C . n 
C 1 300 ASN 300 300 300 ASN ASN C . n 
C 1 301 LYS 301 301 301 LYS LYS C . n 
C 1 302 ILE 302 302 302 ILE ILE C . n 
C 1 303 THR 303 303 303 THR THR C . n 
C 1 304 TYR 304 304 304 TYR TYR C . n 
C 1 305 GLY 305 305 305 GLY GLY C . n 
C 1 306 ALA 306 306 306 ALA ALA C . n 
C 1 307 CYS 307 307 307 CYS CYS C . n 
C 1 308 PRO 308 308 308 PRO PRO C . n 
C 1 309 LYS 309 309 309 LYS LYS C . n 
C 1 310 TYR 310 310 310 TYR TYR C . n 
C 1 311 VAL 311 311 311 VAL VAL C . n 
C 1 312 LYS 312 312 312 LYS LYS C . n 
C 1 313 GLN 313 313 313 GLN GLN C . n 
C 1 314 ASN 314 314 314 ASN ASN C . n 
C 1 315 THR 315 315 315 THR THR C . n 
C 1 316 LEU 316 316 316 LEU LEU C . n 
C 1 317 LYS 317 317 317 LYS LYS C . n 
C 1 318 LEU 318 318 318 LEU LEU C . n 
C 1 319 ALA 319 319 319 ALA ALA C . n 
C 1 320 THR 320 320 320 THR THR C . n 
C 1 321 GLY 321 321 321 GLY GLY C . n 
C 1 322 MET 322 322 322 MET MET C . n 
C 1 323 ARG 323 323 323 ARG ARG C . n 
C 1 324 ASN 324 324 324 ASN ASN C . n 
C 1 325 VAL 325 325 325 VAL VAL C . n 
C 1 326 PRO 326 326 326 PRO PRO C . n 
C 1 327 GLU 327 327 327 GLU GLU C . n 
C 1 328 LYS 328 328 ?   ?   ?   C . n 
C 1 329 GLN 329 329 ?   ?   ?   C . n 
C 1 330 THR 330 330 ?   ?   ?   C . n 
C 1 331 ARG 331 331 ?   ?   ?   C . n 
C 1 332 GLY 332 332 ?   ?   ?   C . n 
C 1 333 LEU 333 333 ?   ?   ?   C . n 
C 1 334 PHE 334 334 ?   ?   ?   C . n 
C 1 335 GLY 335 335 ?   ?   ?   C . n 
C 1 336 ALA 336 336 ?   ?   ?   C . n 
C 1 337 ILE 337 337 337 ILE ILE C . n 
C 1 338 ALA 338 338 338 ALA ALA C . n 
C 1 339 GLY 339 339 339 GLY GLY C . n 
C 1 340 PHE 340 340 340 PHE PHE C . n 
C 1 341 ILE 341 341 341 ILE ILE C . n 
C 1 342 GLU 342 342 342 GLU GLU C . n 
C 1 343 ASN 343 343 343 ASN ASN C . n 
C 1 344 GLY 344 344 344 GLY GLY C . n 
C 1 345 TRP 345 345 345 TRP TRP C . n 
C 1 346 GLU 346 346 346 GLU GLU C . n 
C 1 347 GLY 347 347 347 GLY GLY C . n 
C 1 348 MET 348 348 348 MET MET C . n 
C 1 349 ILE 349 349 349 ILE ILE C . n 
C 1 350 ASP 350 350 350 ASP ASP C . n 
C 1 351 GLY 351 351 351 GLY GLY C . n 
C 1 352 TRP 352 352 352 TRP TRP C . n 
C 1 353 TYR 353 353 353 TYR TYR C . n 
C 1 354 GLY 354 354 354 GLY GLY C . n 
C 1 355 PHE 355 355 355 PHE PHE C . n 
C 1 356 ARG 356 356 356 ARG ARG C . n 
C 1 357 HIS 357 357 357 HIS HIS C . n 
C 1 358 GLN 358 358 358 GLN GLN C . n 
C 1 359 ASN 359 359 359 ASN ASN C . n 
C 1 360 SER 360 360 360 SER SER C . n 
C 1 361 GLU 361 361 361 GLU GLU C . n 
C 1 362 GLY 362 362 362 GLY GLY C . n 
C 1 363 THR 363 363 363 THR THR C . n 
C 1 364 GLY 364 364 364 GLY GLY C . n 
C 1 365 GLN 365 365 365 GLN GLN C . n 
C 1 366 ALA 366 366 366 ALA ALA C . n 
C 1 367 ALA 367 367 367 ALA ALA C . n 
C 1 368 ASP 368 368 368 ASP ASP C . n 
C 1 369 LEU 369 369 369 LEU LEU C . n 
C 1 370 LYS 370 370 370 LYS LYS C . n 
C 1 371 SER 371 371 371 SER SER C . n 
C 1 372 THR 372 372 372 THR THR C . n 
C 1 373 GLN 373 373 373 GLN GLN C . n 
C 1 374 ALA 374 374 374 ALA ALA C . n 
C 1 375 ALA 375 375 375 ALA ALA C . n 
C 1 376 ILE 376 376 376 ILE ILE C . n 
C 1 377 ASP 377 377 377 ASP ASP C . n 
C 1 378 GLN 378 378 378 GLN GLN C . n 
C 1 379 ILE 379 379 379 ILE ILE C . n 
C 1 380 ASN 380 380 380 ASN ASN C . n 
C 1 381 GLY 381 381 381 GLY GLY C . n 
C 1 382 LYS 382 382 382 LYS LYS C . n 
C 1 383 LEU 383 383 383 LEU LEU C . n 
C 1 384 ASN 384 384 384 ASN ASN C . n 
C 1 385 ARG 385 385 385 ARG ARG C . n 
C 1 386 VAL 386 386 386 VAL VAL C . n 
C 1 387 ILE 387 387 387 ILE ILE C . n 
C 1 388 GLU 388 388 388 GLU GLU C . n 
C 1 389 LYS 389 389 389 LYS LYS C . n 
C 1 390 THR 390 390 390 THR THR C . n 
C 1 391 ASN 391 391 391 ASN ASN C . n 
C 1 392 GLU 392 392 392 GLU GLU C . n 
C 1 393 LYS 393 393 393 LYS LYS C . n 
C 1 394 PHE 394 394 394 PHE PHE C . n 
C 1 395 HIS 395 395 395 HIS HIS C . n 
C 1 396 GLN 396 396 396 GLN GLN C . n 
C 1 397 ILE 397 397 397 ILE ILE C . n 
C 1 398 GLU 398 398 398 GLU GLU C . n 
C 1 399 LYS 399 399 399 LYS LYS C . n 
C 1 400 GLU 400 400 400 GLU GLU C . n 
C 1 401 PHE 401 401 401 PHE PHE C . n 
C 1 402 SER 402 402 402 SER SER C . n 
C 1 403 GLU 403 403 403 GLU GLU C . n 
C 1 404 VAL 404 404 404 VAL VAL C . n 
C 1 405 GLU 405 405 405 GLU GLU C . n 
C 1 406 GLY 406 406 406 GLY GLY C . n 
C 1 407 ARG 407 407 407 ARG ARG C . n 
C 1 408 ILE 408 408 408 ILE ILE C . n 
C 1 409 GLN 409 409 409 GLN GLN C . n 
C 1 410 ASP 410 410 410 ASP ASP C . n 
C 1 411 LEU 411 411 411 LEU LEU C . n 
C 1 412 GLU 412 412 412 GLU GLU C . n 
C 1 413 LYS 413 413 413 LYS LYS C . n 
C 1 414 TYR 414 414 414 TYR TYR C . n 
C 1 415 VAL 415 415 415 VAL VAL C . n 
C 1 416 GLU 416 416 416 GLU GLU C . n 
C 1 417 ASP 417 417 417 ASP ASP C . n 
C 1 418 THR 418 418 418 THR THR C . n 
C 1 419 LYS 419 419 419 LYS LYS C . n 
C 1 420 VAL 420 420 420 VAL VAL C . n 
C 1 421 ASP 421 421 421 ASP ASP C . n 
C 1 422 LEU 422 422 422 LEU LEU C . n 
C 1 423 TRP 423 423 423 TRP TRP C . n 
C 1 424 SER 424 424 424 SER SER C . n 
C 1 425 TYR 425 425 425 TYR TYR C . n 
C 1 426 ASN 426 426 426 ASN ASN C . n 
C 1 427 ALA 427 427 427 ALA ALA C . n 
C 1 428 GLU 428 428 428 GLU GLU C . n 
C 1 429 LEU 429 429 429 LEU LEU C . n 
C 1 430 LEU 430 430 430 LEU LEU C . n 
C 1 431 VAL 431 431 431 VAL VAL C . n 
C 1 432 ALA 432 432 432 ALA ALA C . n 
C 1 433 LEU 433 433 433 LEU LEU C . n 
C 1 434 GLU 434 434 434 GLU GLU C . n 
C 1 435 ASN 435 435 435 ASN ASN C . n 
C 1 436 GLN 436 436 436 GLN GLN C . n 
C 1 437 HIS 437 437 437 HIS HIS C . n 
C 1 438 THR 438 438 438 THR THR C . n 
C 1 439 ILE 439 439 439 ILE ILE C . n 
C 1 440 ASP 440 440 440 ASP ASP C . n 
C 1 441 LEU 441 441 441 LEU LEU C . n 
C 1 442 THR 442 442 442 THR THR C . n 
C 1 443 ASP 443 443 443 ASP ASP C . n 
C 1 444 SER 444 444 444 SER SER C . n 
C 1 445 GLU 445 445 445 GLU GLU C . n 
C 1 446 MET 446 446 446 MET MET C . n 
C 1 447 ASN 447 447 447 ASN ASN C . n 
C 1 448 LYS 448 448 448 LYS LYS C . n 
C 1 449 LEU 449 449 449 LEU LEU C . n 
C 1 450 PHE 450 450 450 PHE PHE C . n 
C 1 451 GLU 451 451 451 GLU GLU C . n 
C 1 452 LYS 452 452 452 LYS LYS C . n 
C 1 453 THR 453 453 453 THR THR C . n 
C 1 454 ARG 454 454 454 ARG ARG C . n 
C 1 455 ARG 455 455 455 ARG ARG C . n 
C 1 456 GLN 456 456 456 GLN GLN C . n 
C 1 457 LEU 457 457 457 LEU LEU C . n 
C 1 458 ARG 458 458 458 ARG ARG C . n 
C 1 459 GLU 459 459 459 GLU GLU C . n 
C 1 460 ASN 460 460 460 ASN ASN C . n 
C 1 461 ALA 461 461 461 ALA ALA C . n 
C 1 462 GLU 462 462 462 GLU GLU C . n 
C 1 463 ASP 463 463 463 ASP ASP C . n 
C 1 464 MET 464 464 464 MET MET C . n 
C 1 465 GLY 465 465 465 GLY GLY C . n 
C 1 466 ASN 466 466 466 ASN ASN C . n 
C 1 467 GLY 467 467 467 GLY GLY C . n 
C 1 468 CYS 468 468 468 CYS CYS C . n 
C 1 469 PHE 469 469 469 PHE PHE C . n 
C 1 470 LYS 470 470 470 LYS LYS C . n 
C 1 471 ILE 471 471 471 ILE ILE C . n 
C 1 472 TYR 472 472 472 TYR TYR C . n 
C 1 473 HIS 473 473 473 HIS HIS C . n 
C 1 474 LYS 474 474 474 LYS LYS C . n 
C 1 475 CYS 475 475 475 CYS CYS C . n 
C 1 476 ASP 476 476 476 ASP ASP C . n 
C 1 477 ASN 477 477 477 ASN ASN C . n 
C 1 478 ALA 478 478 478 ALA ALA C . n 
C 1 479 CYS 479 479 479 CYS CYS C . n 
C 1 480 ILE 480 480 480 ILE ILE C . n 
C 1 481 GLU 481 481 481 GLU GLU C . n 
C 1 482 SER 482 482 482 SER SER C . n 
C 1 483 ILE 483 483 483 ILE ILE C . n 
C 1 484 ARG 484 484 484 ARG ARG C . n 
C 1 485 ASN 485 485 485 ASN ASN C . n 
C 1 486 GLY 486 486 486 GLY GLY C . n 
C 1 487 THR 487 487 487 THR THR C . n 
C 1 488 TYR 488 488 488 TYR TYR C . n 
C 1 489 ASP 489 489 489 ASP ASP C . n 
C 1 490 HIS 490 490 490 HIS HIS C . n 
C 1 491 ASP 491 491 491 ASP ASP C . n 
C 1 492 ILE 492 492 492 ILE ILE C . n 
C 1 493 TYR 493 493 493 TYR TYR C . n 
C 1 494 ARG 494 494 494 ARG ARG C . n 
C 1 495 ASP 495 495 495 ASP ASP C . n 
C 1 496 GLU 496 496 496 GLU GLU C . n 
C 1 497 ALA 497 497 497 ALA ALA C . n 
C 1 498 LEU 498 498 498 LEU LEU C . n 
C 1 499 ASN 499 499 499 ASN ASN C . n 
C 1 500 ASN 500 500 500 ASN ASN C . n 
C 1 501 ARG 501 501 501 ARG ARG C . n 
C 1 502 PHE 502 502 502 PHE PHE C . n 
C 1 503 GLN 503 503 ?   ?   ?   C . n 
C 1 504 ILE 504 504 ?   ?   ?   C . n 
C 1 505 ARG 505 505 ?   ?   ?   C . n 
C 1 506 GLY 506 506 ?   ?   ?   C . n 
C 1 507 VAL 507 507 ?   ?   ?   C . n 
C 1 508 GLU 508 508 ?   ?   ?   C . n 
C 1 509 PHE 509 509 ?   ?   ?   C . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
D 2 NAG 1 D NAG 1 A NAG 611 n 
D 2 NAG 2 D NAG 2 A NAG 612 n 
D 2 BMA 3 D BMA 3 A BMA 613 n 
D 2 MAN 4 D MAN 4 A MAN 614 n 
D 2 MAN 5 D MAN 5 A MAN 615 n 
E 3 NAG 1 E NAG 1 A NAG 621 n 
E 3 NAG 2 E NAG 2 A NAG 622 n 
F 2 NAG 1 F NAG 1 B NAG 611 n 
F 2 NAG 2 F NAG 2 B NAG 612 n 
F 2 BMA 3 F BMA 3 B BMA 613 n 
F 2 MAN 4 F MAN 4 B MAN 614 n 
F 2 MAN 5 F MAN 5 B MAN 615 n 
G 3 NAG 1 G NAG 1 B NAG 621 n 
G 3 NAG 2 G NAG 2 B NAG 622 n 
H 2 NAG 1 H NAG 1 C NAG 611 n 
H 2 NAG 2 H NAG 2 C NAG 612 n 
H 2 BMA 3 H BMA 3 C BMA 613 n 
H 2 MAN 4 H MAN 4 C MAN 614 n 
H 2 MAN 5 H MAN 5 C MAN 615 n 
I 3 NAG 1 I NAG 1 C NAG 621 n 
I 3 NAG 2 I NAG 2 C NAG 622 n 
J 4 GAL 1 J GAL 1 D GAL 2   n 
J 4 SIA 2 J SIA 2 D SIA 1   n 
K 4 GAL 1 K GAL 1 F GAL 2   n 
K 4 SIA 2 K SIA 2 F SIA 1   n 
L 4 GAL 1 L GAL 1 E GAL 2   n 
L 4 SIA 2 L SIA 2 E SIA 1   n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 GAL ? ? GAL ? ? 'SUBJECT OF INVESTIGATION' ? 
2 SIA ? ? SIA ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
M 5 NAG 1 601 601 NAG NAG A . 
N 5 NAG 1 601 601 NAG NAG B . 
O 5 NAG 1 601 601 NAG NAG C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B ASP 463 ? OD1 ? B ASP 463 OD1 
2 1 Y 1 B ASP 463 ? OD2 ? B ASP 463 OD2 
3 1 Y 1 C SER 126 ? OG  ? C SER 126 OG  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZW5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZW5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZW5 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ZW5 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 12068 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.524 ? 16364 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.869 ? 1778  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.052 ? 1871  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 2104  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZW5 
_struct.title                        
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus G228 mutant complexed with avian receptor analog LSTa' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZW5 
_struct_keywords.text            'H3N8, hemagglutinin, avian receptor, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 2 ? 
G N N 3 ? 
H N N 2 ? 
I N N 3 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 5 ? 
N N N 5 ? 
O N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    8ZW5 
_struct_ref.pdbx_db_accession          8ZW5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZW5 A 1 ? 509 ? 8ZW5 1 ? 509 ? 1 509 
2 1 8ZW5 B 1 ? 509 ? 8ZW5 1 ? 509 ? 1 509 
3 1 8ZW5 C 1 ? 509 ? 8ZW5 1 ? 509 ? 1 509 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 67  ? GLY A 74  ? THR A 67  GLY A 74  1 ? 8  
HELX_P HELX_P2  AA2 ASP A 75  ? GLN A 82  ? ASP A 75  GLN A 82  5 ? 8  
HELX_P HELX_P3  AA3 ASP A 106 ? GLY A 118 ? ASP A 106 GLY A 118 1 ? 13 
HELX_P HELX_P4  AA4 THR A 189 ? TYR A 197 ? THR A 189 TYR A 197 1 ? 9  
HELX_P HELX_P5  AA5 LEU A 369 ? ASN A 380 ? LEU A 369 ASN A 380 1 ? 12 
HELX_P HELX_P6  AA6 LYS A 382 ? VAL A 386 ? LYS A 382 VAL A 386 5 ? 5  
HELX_P HELX_P7  AA7 GLY A 406 ? LEU A 457 ? GLY A 406 LEU A 457 1 ? 52 
HELX_P HELX_P8  AA8 ASP A 476 ? GLY A 486 ? ASP A 476 GLY A 486 1 ? 11 
HELX_P HELX_P9  AA9 HIS A 490 ? ILE A 492 ? HIS A 490 ILE A 492 5 ? 3  
HELX_P HELX_P10 AB1 TYR A 493 ? PHE A 502 ? TYR A 493 PHE A 502 1 ? 10 
HELX_P HELX_P11 AB2 THR B 67  ? GLY B 74  ? THR B 67  GLY B 74  1 ? 8  
HELX_P HELX_P12 AB3 ASP B 75  ? GLN B 82  ? ASP B 75  GLN B 82  5 ? 8  
HELX_P HELX_P13 AB4 ASP B 106 ? GLY B 118 ? ASP B 106 GLY B 118 1 ? 13 
HELX_P HELX_P14 AB5 THR B 189 ? TYR B 197 ? THR B 189 TYR B 197 1 ? 9  
HELX_P HELX_P15 AB6 LEU B 369 ? ASN B 380 ? LEU B 369 ASN B 380 1 ? 12 
HELX_P HELX_P16 AB7 LYS B 382 ? VAL B 386 ? LYS B 382 VAL B 386 5 ? 5  
HELX_P HELX_P17 AB8 GLY B 406 ? LEU B 457 ? GLY B 406 LEU B 457 1 ? 52 
HELX_P HELX_P18 AB9 ASP B 476 ? GLY B 486 ? ASP B 476 GLY B 486 1 ? 11 
HELX_P HELX_P19 AC1 HIS B 490 ? ILE B 492 ? HIS B 490 ILE B 492 5 ? 3  
HELX_P HELX_P20 AC2 TYR B 493 ? PHE B 502 ? TYR B 493 PHE B 502 1 ? 10 
HELX_P HELX_P21 AC3 THR C 67  ? GLY C 74  ? THR C 67  GLY C 74  1 ? 8  
HELX_P HELX_P22 AC4 ASP C 75  ? GLN C 82  ? ASP C 75  GLN C 82  5 ? 8  
HELX_P HELX_P23 AC5 ASP C 106 ? GLY C 118 ? ASP C 106 GLY C 118 1 ? 13 
HELX_P HELX_P24 AC6 THR C 189 ? TYR C 197 ? THR C 189 TYR C 197 1 ? 9  
HELX_P HELX_P25 AC7 ASP C 368 ? ASN C 380 ? ASP C 368 ASN C 380 1 ? 13 
HELX_P HELX_P26 AC8 LYS C 382 ? VAL C 386 ? LYS C 382 VAL C 386 5 ? 5  
HELX_P HELX_P27 AC9 GLY C 406 ? LEU C 457 ? GLY C 406 LEU C 457 1 ? 52 
HELX_P HELX_P28 AD1 ASP C 476 ? GLY C 486 ? ASP C 476 GLY C 486 1 ? 11 
HELX_P HELX_P29 AD2 HIS C 490 ? ILE C 492 ? HIS C 490 ILE C 492 5 ? 3  
HELX_P HELX_P30 AD3 TYR C 493 ? PHE C 502 ? TYR C 493 PHE C 502 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 16  SG  ? ? ? 1_555 A CYS 468 SG ? ? A CYS 16  A CYS 468 1_555 ? ? ? ? ? ? ? 2.028 ? ?               
disulf2  disulf ?    ? A CYS 54  SG  ? ? ? 1_555 A CYS 279 SG ? ? A CYS 54  A CYS 279 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf3  disulf ?    ? A CYS 66  SG  ? ? ? 1_555 A CYS 78  SG ? ? A CYS 66  A CYS 78  1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf4  disulf ?    ? A CYS 99  SG  ? ? ? 1_555 A CYS 141 SG ? ? A CYS 99  A CYS 141 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf5  disulf ?    ? A CYS 283 SG  ? ? ? 1_555 A CYS 307 SG ? ? A CYS 283 A CYS 307 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf6  disulf ?    ? A CYS 475 SG  ? ? ? 1_555 A CYS 479 SG ? ? A CYS 475 A CYS 479 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf7  disulf ?    ? B CYS 16  SG  ? ? ? 1_555 B CYS 468 SG ? ? B CYS 16  B CYS 468 1_555 ? ? ? ? ? ? ? 2.027 ? ?               
disulf8  disulf ?    ? B CYS 54  SG  ? ? ? 1_555 B CYS 279 SG ? ? B CYS 54  B CYS 279 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf9  disulf ?    ? B CYS 66  SG  ? ? ? 1_555 B CYS 78  SG ? ? B CYS 66  B CYS 78  1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf10 disulf ?    ? B CYS 99  SG  ? ? ? 1_555 B CYS 141 SG ? ? B CYS 99  B CYS 141 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf11 disulf ?    ? B CYS 283 SG  ? ? ? 1_555 B CYS 307 SG ? ? B CYS 283 B CYS 307 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf12 disulf ?    ? B CYS 475 SG  ? ? ? 1_555 B CYS 479 SG ? ? B CYS 475 B CYS 479 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf13 disulf ?    ? C CYS 16  SG  ? ? ? 1_555 C CYS 468 SG ? ? C CYS 16  C CYS 468 1_555 ? ? ? ? ? ? ? 2.023 ? ?               
disulf14 disulf ?    ? C CYS 54  SG  ? ? ? 1_555 C CYS 279 SG ? ? C CYS 54  C CYS 279 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf15 disulf ?    ? C CYS 66  SG  ? ? ? 1_555 C CYS 78  SG ? ? C CYS 66  C CYS 78  1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf16 disulf ?    ? C CYS 99  SG  ? ? ? 1_555 C CYS 141 SG ? ? C CYS 99  C CYS 141 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf17 disulf ?    ? C CYS 283 SG  ? ? ? 1_555 C CYS 307 SG ? ? C CYS 283 C CYS 307 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf18 disulf ?    ? C CYS 475 SG  ? ? ? 1_555 C CYS 479 SG ? ? C CYS 475 C CYS 479 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1  covale one  ? A ASN 40  ND2 ? ? ? 1_555 M NAG .   C1 ? ? A ASN 40  A NAG 601 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale2  covale one  ? A ASN 167 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 167 D NAG 1   1_555 ? ? ? ? ? ? ? 1.445 ? N-Glycosylation 
covale3  covale one  ? A ASN 287 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 287 E NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale4  covale one  ? B ASN 40  ND2 ? ? ? 1_555 N NAG .   C1 ? ? B ASN 40  B NAG 601 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale5  covale one  ? B ASN 167 ND2 ? ? ? 1_555 F NAG .   C1 ? ? B ASN 167 F NAG 1   1_555 ? ? ? ? ? ? ? 1.460 ? N-Glycosylation 
covale6  covale one  ? B ASN 287 ND2 ? ? ? 1_555 G NAG .   C1 ? ? B ASN 287 G NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale7  covale one  ? C ASN 40  ND2 ? ? ? 1_555 O NAG .   C1 ? ? C ASN 40  C NAG 601 1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale8  covale one  ? C ASN 167 ND2 ? ? ? 1_555 H NAG .   C1 ? ? C ASN 167 H NAG 1   1_555 ? ? ? ? ? ? ? 1.446 ? N-Glycosylation 
covale9  covale one  ? C ASN 287 ND2 ? ? ? 1_555 I NAG .   C1 ? ? C ASN 287 I NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale10 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale11 covale both ? D NAG .   O4  ? ? ? 1_555 D BMA .   C1 ? ? D NAG 2   D BMA 3   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale12 covale both ? D BMA .   O3  ? ? ? 1_555 D MAN .   C1 ? ? D BMA 3   D MAN 4   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale13 covale both ? D BMA .   O6  ? ? ? 1_555 D MAN .   C1 ? ? D BMA 3   D MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale14 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? E NAG 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale15 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale16 covale both ? F NAG .   O4  ? ? ? 1_555 F BMA .   C1 ? ? F NAG 2   F BMA 3   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale17 covale both ? F BMA .   O3  ? ? ? 1_555 F MAN .   C1 ? ? F BMA 3   F MAN 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale18 covale both ? F BMA .   O6  ? ? ? 1_555 F MAN .   C1 ? ? F BMA 3   F MAN 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale19 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale20 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale21 covale both ? H NAG .   O4  ? ? ? 1_555 H BMA .   C1 ? ? H NAG 2   H BMA 3   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale22 covale both ? H BMA .   O3  ? ? ? 1_555 H MAN .   C1 ? ? H BMA 3   H MAN 4   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale23 covale both ? H BMA .   O6  ? ? ? 1_555 H MAN .   C1 ? ? H BMA 3   H MAN 5   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale24 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? I NAG 1   I NAG 2   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale25 covale both ? J GAL .   O3  ? ? ? 1_555 J SIA .   C2 ? ? J GAL 1   J SIA 2   1_555 ? ? ? ? ? ? ? 1.374 ? ?               
covale26 covale both ? K GAL .   O3  ? ? ? 1_555 K SIA .   C2 ? ? K GAL 1   K SIA 2   1_555 ? ? ? ? ? ? ? 1.374 ? ?               
covale27 covale both ? L GAL .   O3  ? ? ? 1_555 L SIA .   C2 ? ? L GAL 1   L SIA 2   1_555 ? ? ? ? ? ? ? 1.375 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG D .   ? ASN A 167 ? NAG D 1   ? 1_555 ASN A 167 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG E .   ? ASN A 287 ? NAG E 1   ? 1_555 ASN A 287 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG F .   ? ASN B 167 ? NAG F 1   ? 1_555 ASN B 167 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG G .   ? ASN B 287 ? NAG G 1   ? 1_555 ASN B 287 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG H .   ? ASN C 167 ? NAG H 1   ? 1_555 ASN C 167 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG I .   ? ASN C 287 ? NAG I 1   ? 1_555 ASN C 287 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG M .   ? ASN A 40  ? NAG A 601 ? 1_555 ASN A 40  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG N .   ? ASN B 40  ? NAG B 601 ? 1_555 ASN B 40  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  NAG O .   ? ASN C 40  ? NAG C 601 ? 1_555 ASN C 40  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
10 CYS A 16  ? CYS A 468 ? CYS A 16  ? 1_555 CYS A 468 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS A 54  ? CYS A 279 ? CYS A 54  ? 1_555 CYS A 279 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS A 66  ? CYS A 78  ? CYS A 66  ? 1_555 CYS A 78  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS A 99  ? CYS A 141 ? CYS A 99  ? 1_555 CYS A 141 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
14 CYS A 283 ? CYS A 307 ? CYS A 283 ? 1_555 CYS A 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
15 CYS A 475 ? CYS A 479 ? CYS A 475 ? 1_555 CYS A 479 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
16 CYS B 16  ? CYS B 468 ? CYS B 16  ? 1_555 CYS B 468 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS B 54  ? CYS B 279 ? CYS B 54  ? 1_555 CYS B 279 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS B 66  ? CYS B 78  ? CYS B 66  ? 1_555 CYS B 78  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
19 CYS B 99  ? CYS B 141 ? CYS B 99  ? 1_555 CYS B 141 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS B 283 ? CYS B 307 ? CYS B 283 ? 1_555 CYS B 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
21 CYS B 475 ? CYS B 479 ? CYS B 475 ? 1_555 CYS B 479 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
22 CYS C 16  ? CYS C 468 ? CYS C 16  ? 1_555 CYS C 468 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
23 CYS C 54  ? CYS C 279 ? CYS C 54  ? 1_555 CYS C 279 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
24 CYS C 66  ? CYS C 78  ? CYS C 66  ? 1_555 CYS C 78  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
25 CYS C 99  ? CYS C 141 ? CYS C 99  ? 1_555 CYS C 141 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
26 CYS C 283 ? CYS C 307 ? CYS C 283 ? 1_555 CYS C 307 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
27 CYS C 475 ? CYS C 479 ? CYS C 475 ? 1_555 CYS C 479 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASN 56 A . ? ASN 56 A PRO 57 A ? PRO 57 A 1 1.22 
2 ASN 56 B . ? ASN 56 B PRO 57 B ? PRO 57 B 1 1.60 
3 ASN 56 C . ? ASN 56 C PRO 57 C ? PRO 57 C 1 1.53 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
AA7 ? 5 ? 
AA8 ? 5 ? 
AA9 ? 2 ? 
AB1 ? 2 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 5 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 3 ? 
AB8 ? 2 ? 
AB9 ? 3 ? 
AC1 ? 5 ? 
AC2 ? 5 ? 
AC3 ? 2 ? 
AC4 ? 2 ? 
AC5 ? 4 ? 
AC6 ? 4 ? 
AC7 ? 5 ? 
AC8 ? 2 ? 
AC9 ? 2 ? 
AD1 ? 3 ? 
AD2 ? 2 ? 
AD3 ? 3 ? 
AD4 ? 5 ? 
AD5 ? 5 ? 
AD6 ? 2 ? 
AD7 ? 2 ? 
AD8 ? 4 ? 
AD9 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA5 1 2 ? parallel      
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? parallel      
AB8 1 2 ? parallel      
AB9 1 2 ? parallel      
AB9 2 3 ? parallel      
AC1 1 2 ? parallel      
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC1 4 5 ? anti-parallel 
AC2 1 2 ? parallel      
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC7 4 5 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AD1 1 2 ? parallel      
AD1 2 3 ? parallel      
AD2 1 2 ? parallel      
AD3 1 2 ? parallel      
AD3 2 3 ? parallel      
AD4 1 2 ? parallel      
AD4 2 3 ? anti-parallel 
AD4 3 4 ? anti-parallel 
AD4 4 5 ? anti-parallel 
AD5 1 2 ? parallel      
AD5 2 3 ? anti-parallel 
AD5 3 4 ? anti-parallel 
AD5 4 5 ? anti-parallel 
AD6 1 2 ? anti-parallel 
AD7 1 2 ? anti-parallel 
AD8 1 2 ? anti-parallel 
AD8 2 3 ? anti-parallel 
AD8 3 4 ? anti-parallel 
AD9 1 2 ? anti-parallel 
AD9 2 3 ? anti-parallel 
AD9 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 364 ? ASP A 368 ? GLY A 364 ASP A 368 
AA1 2 TYR A 353 ? GLN A 358 ? TYR A 353 GLN A 358 
AA1 3 ALA A 13  ? HIS A 19  ? ALA A 13  HIS A 19  
AA1 4 CYS A 468 ? ILE A 471 ? CYS A 468 ILE A 471 
AA1 5 ALA A 461 ? ASP A 463 ? ALA A 461 ASP A 463 
AA2 1 THR A 26  ? VAL A 28  ? THR A 26  VAL A 28  
AA2 2 ILE A 36  ? VAL A 38  ? ILE A 36  VAL A 38  
AA3 1 ALA A 41  ? GLU A 43  ? ALA A 41  GLU A 43  
AA3 2 LYS A 317 ? ALA A 319 ? LYS A 317 ALA A 319 
AA4 1 VAL A 45  ? GLN A 46  ? VAL A 45  GLN A 46  
AA4 2 PHE A 296 ? GLN A 297 ? PHE A 296 GLN A 297 
AA4 3 LYS A 309 ? TYR A 310 ? LYS A 309 TYR A 310 
AA5 1 ILE A 53  ? ASN A 56  ? ILE A 53  ASN A 56  
AA5 2 ILE A 276 ? ILE A 280 ? ILE A 276 ILE A 280 
AA6 1 VAL A 60  ? GLY A 63  ? VAL A 60  GLY A 63  
AA6 2 LEU A 88  ? GLU A 91  ? LEU A 88  GLU A 91  
AA6 3 SER A 268 ? ARG A 271 ? SER A 268 ARG A 271 
AA7 1 TYR A 102 ? ASP A 103 ? TYR A 102 ASP A 103 
AA7 2 ARG A 231 ? VAL A 239 ? ARG A 231 VAL A 239 
AA7 3 LYS A 178 ? HIS A 186 ? LYS A 178 HIS A 186 
AA7 4 GLY A 258 ? LYS A 261 ? GLY A 258 LYS A 261 
AA7 5 PHE A 122 ? THR A 124 ? PHE A 122 THR A 124 
AA8 1 TYR A 102 ? ASP A 103 ? TYR A 102 ASP A 103 
AA8 2 ARG A 231 ? VAL A 239 ? ARG A 231 VAL A 239 
AA8 3 LYS A 178 ? HIS A 186 ? LYS A 178 HIS A 186 
AA8 4 LEU A 253 ? PRO A 256 ? LEU A 253 PRO A 256 
AA8 5 LEU A 153 ? TRP A 155 ? LEU A 153 TRP A 155 
AA9 1 VAL A 132 ? SER A 133 ? VAL A 132 SER A 133 
AA9 2 THR A 157 ? LYS A 158 ? THR A 157 LYS A 158 
AB1 1 SER A 138 ? ARG A 143 ? SER A 138 ARG A 143 
AB1 2 ALA A 146 ? GLY A 148 ? ALA A 146 GLY A 148 
AB2 1 LEU A 166 ? PRO A 171 ? LEU A 166 PRO A 171 
AB2 2 VAL A 244 ? GLY A 251 ? VAL A 244 GLY A 251 
AB2 3 ARG A 203 ? SER A 207 ? ARG A 203 SER A 207 
AB2 4 GLN A 212 ? ILE A 215 ? GLN A 212 ILE A 215 
AB3 1 GLY A 288 ? ILE A 290 ? GLY A 288 ILE A 290 
AB3 2 CYS A 283 ? THR A 285 ? CYS A 283 THR A 285 
AB3 3 TYR A 304 ? CYS A 307 ? TYR A 304 CYS A 307 
AB3 4 ASN A 391 ? LYS A 393 ? ASN A 391 LYS A 393 
AB4 1 GLY B 364 ? ASP B 368 ? GLY B 364 ASP B 368 
AB4 2 TYR B 353 ? GLN B 358 ? TYR B 353 GLN B 358 
AB4 3 ALA B 13  ? HIS B 19  ? ALA B 13  HIS B 19  
AB4 4 CYS B 468 ? ILE B 471 ? CYS B 468 ILE B 471 
AB4 5 ALA B 461 ? ASP B 463 ? ALA B 461 ASP B 463 
AB5 1 THR B 26  ? VAL B 28  ? THR B 26  VAL B 28  
AB5 2 ILE B 36  ? VAL B 38  ? ILE B 36  VAL B 38  
AB6 1 ALA B 41  ? GLU B 43  ? ALA B 41  GLU B 43  
AB6 2 LYS B 317 ? ALA B 319 ? LYS B 317 ALA B 319 
AB7 1 VAL B 45  ? GLN B 46  ? VAL B 45  GLN B 46  
AB7 2 PHE B 296 ? GLN B 297 ? PHE B 296 GLN B 297 
AB7 3 LYS B 309 ? TYR B 310 ? LYS B 309 TYR B 310 
AB8 1 ILE B 53  ? ASN B 56  ? ILE B 53  ASN B 56  
AB8 2 ILE B 276 ? ILE B 280 ? ILE B 276 ILE B 280 
AB9 1 VAL B 60  ? ASP B 62  ? VAL B 60  ASP B 62  
AB9 2 LEU B 88  ? GLU B 91  ? LEU B 88  GLU B 91  
AB9 3 SER B 268 ? ARG B 271 ? SER B 268 ARG B 271 
AC1 1 TYR B 102 ? ASP B 103 ? TYR B 102 ASP B 103 
AC1 2 ARG B 231 ? VAL B 239 ? ARG B 231 VAL B 239 
AC1 3 LYS B 178 ? HIS B 186 ? LYS B 178 HIS B 186 
AC1 4 GLY B 258 ? LYS B 261 ? GLY B 258 LYS B 261 
AC1 5 PHE B 122 ? THR B 124 ? PHE B 122 THR B 124 
AC2 1 TYR B 102 ? ASP B 103 ? TYR B 102 ASP B 103 
AC2 2 ARG B 231 ? VAL B 239 ? ARG B 231 VAL B 239 
AC2 3 LYS B 178 ? HIS B 186 ? LYS B 178 HIS B 186 
AC2 4 LEU B 253 ? PRO B 256 ? LEU B 253 PRO B 256 
AC2 5 LEU B 153 ? TRP B 155 ? LEU B 153 TRP B 155 
AC3 1 VAL B 132 ? SER B 133 ? VAL B 132 SER B 133 
AC3 2 THR B 157 ? LYS B 158 ? THR B 157 LYS B 158 
AC4 1 SER B 138 ? ARG B 143 ? SER B 138 ARG B 143 
AC4 2 ALA B 146 ? GLY B 148 ? ALA B 146 GLY B 148 
AC5 1 LEU B 166 ? PRO B 171 ? LEU B 166 PRO B 171 
AC5 2 VAL B 244 ? GLY B 251 ? VAL B 244 GLY B 251 
AC5 3 ARG B 203 ? SER B 207 ? ARG B 203 SER B 207 
AC5 4 GLN B 212 ? ILE B 215 ? GLN B 212 ILE B 215 
AC6 1 GLY B 288 ? ILE B 290 ? GLY B 288 ILE B 290 
AC6 2 CYS B 283 ? THR B 285 ? CYS B 283 THR B 285 
AC6 3 TYR B 304 ? CYS B 307 ? TYR B 304 CYS B 307 
AC6 4 ASN B 391 ? LYS B 393 ? ASN B 391 LYS B 393 
AC7 1 GLY C 364 ? ALA C 367 ? GLY C 364 ALA C 367 
AC7 2 TYR C 353 ? GLN C 358 ? TYR C 353 GLN C 358 
AC7 3 ALA C 13  ? HIS C 19  ? ALA C 13  HIS C 19  
AC7 4 CYS C 468 ? ILE C 471 ? CYS C 468 ILE C 471 
AC7 5 ALA C 461 ? ASP C 463 ? ALA C 461 ASP C 463 
AC8 1 THR C 26  ? VAL C 28  ? THR C 26  VAL C 28  
AC8 2 ILE C 36  ? VAL C 38  ? ILE C 36  VAL C 38  
AC9 1 ALA C 41  ? GLU C 43  ? ALA C 41  GLU C 43  
AC9 2 LYS C 317 ? ALA C 319 ? LYS C 317 ALA C 319 
AD1 1 VAL C 45  ? GLN C 46  ? VAL C 45  GLN C 46  
AD1 2 PHE C 296 ? GLN C 297 ? PHE C 296 GLN C 297 
AD1 3 LYS C 309 ? TYR C 310 ? LYS C 309 TYR C 310 
AD2 1 ILE C 53  ? ASN C 56  ? ILE C 53  ASN C 56  
AD2 2 ILE C 276 ? ILE C 280 ? ILE C 276 ILE C 280 
AD3 1 VAL C 60  ? ASP C 62  ? VAL C 60  ASP C 62  
AD3 2 LEU C 88  ? GLU C 91  ? LEU C 88  GLU C 91  
AD3 3 SER C 268 ? ARG C 271 ? SER C 268 ARG C 271 
AD4 1 TYR C 102 ? ASP C 103 ? TYR C 102 ASP C 103 
AD4 2 ARG C 231 ? VAL C 239 ? ARG C 231 VAL C 239 
AD4 3 LYS C 178 ? HIS C 186 ? LYS C 178 HIS C 186 
AD4 4 GLY C 258 ? LYS C 261 ? GLY C 258 LYS C 261 
AD4 5 PHE C 122 ? THR C 124 ? PHE C 122 THR C 124 
AD5 1 TYR C 102 ? ASP C 103 ? TYR C 102 ASP C 103 
AD5 2 ARG C 231 ? VAL C 239 ? ARG C 231 VAL C 239 
AD5 3 LYS C 178 ? HIS C 186 ? LYS C 178 HIS C 186 
AD5 4 LEU C 253 ? PRO C 256 ? LEU C 253 PRO C 256 
AD5 5 LEU C 153 ? TRP C 155 ? LEU C 153 TRP C 155 
AD6 1 VAL C 132 ? SER C 133 ? VAL C 132 SER C 133 
AD6 2 THR C 157 ? LYS C 158 ? THR C 157 LYS C 158 
AD7 1 SER C 138 ? ARG C 143 ? SER C 138 ARG C 143 
AD7 2 ALA C 146 ? GLY C 148 ? ALA C 146 GLY C 148 
AD8 1 LEU C 166 ? PRO C 171 ? LEU C 166 PRO C 171 
AD8 2 VAL C 244 ? GLY C 251 ? VAL C 244 GLY C 251 
AD8 3 ARG C 203 ? SER C 207 ? ARG C 203 SER C 207 
AD8 4 GLN C 212 ? ILE C 215 ? GLN C 212 ILE C 215 
AD9 1 GLY C 288 ? ILE C 290 ? GLY C 288 ILE C 290 
AD9 2 CYS C 283 ? THR C 285 ? CYS C 283 THR C 285 
AD9 3 TYR C 304 ? CYS C 307 ? TYR C 304 CYS C 307 
AD9 4 ASN C 391 ? LYS C 393 ? ASN C 391 LYS C 393 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ASP A 368 ? O ASP A 368 N TYR A 353 ? N TYR A 353 
AA1 2 3 O GLN A 358 ? O GLN A 358 N THR A 14  ? N THR A 14  
AA1 3 4 N LEU A 15  ? N LEU A 15  O PHE A 469 ? O PHE A 469 
AA1 4 5 O LYS A 470 ? O LYS A 470 N GLU A 462 ? N GLU A 462 
AA2 1 2 N THR A 26  ? N THR A 26  O VAL A 38  ? O VAL A 38  
AA3 1 2 N THR A 42  ? N THR A 42  O LEU A 318 ? O LEU A 318 
AA4 1 2 N GLN A 46  ? N GLN A 46  O PHE A 296 ? O PHE A 296 
AA4 2 3 N GLN A 297 ? N GLN A 297 O LYS A 309 ? O LYS A 309 
AA5 1 2 N ILE A 53  ? N ILE A 53  O GLU A 277 ? O GLU A 277 
AA6 1 2 N LEU A 61  ? N LEU A 61  O VAL A 90  ? O VAL A 90  
AA6 2 3 N GLU A 91  ? N GLU A 91  O MET A 270 ? O MET A 270 
AA7 1 2 N ASP A 103 ? N ASP A 103 O ILE A 232 ? O ILE A 232 
AA7 2 3 O TYR A 235 ? O TYR A 235 N TRP A 182 ? N TRP A 182 
AA7 3 4 N LEU A 179 ? N LEU A 179 O PHE A 260 ? O PHE A 260 
AA7 4 5 O PHE A 259 ? O PHE A 259 N ILE A 123 ? N ILE A 123 
AA8 1 2 N ASP A 103 ? N ASP A 103 O ILE A 232 ? O ILE A 232 
AA8 2 3 O TYR A 235 ? O TYR A 235 N TRP A 182 ? N TRP A 182 
AA8 3 4 N GLY A 183 ? N GLY A 183 O ILE A 254 ? O ILE A 254 
AA8 4 5 O ALA A 255 ? O ALA A 255 N ASN A 154 ? N ASN A 154 
AA9 1 2 N SER A 133 ? N SER A 133 O THR A 157 ? O THR A 157 
AB1 1 2 N CYS A 141 ? N CYS A 141 O GLY A 148 ? O GLY A 148 
AB2 1 2 N LEU A 166 ? N LEU A 166 O SER A 249 ? O SER A 249 
AB2 2 3 O ASN A 248 ? O ASN A 248 N THR A 205 ? N THR A 205 
AB2 3 4 N VAL A 206 ? N VAL A 206 O GLN A 213 ? O GLN A 213 
AB3 1 2 O ILE A 290 ? O ILE A 290 N CYS A 283 ? N CYS A 283 
AB3 2 3 N ILE A 284 ? N ILE A 284 O TYR A 304 ? O TYR A 304 
AB3 3 4 N GLY A 305 ? N GLY A 305 O LYS A 393 ? O LYS A 393 
AB4 1 2 O ASP B 368 ? O ASP B 368 N TYR B 353 ? N TYR B 353 
AB4 2 3 O ARG B 356 ? O ARG B 356 N CYS B 16  ? N CYS B 16  
AB4 3 4 N LEU B 15  ? N LEU B 15  O PHE B 469 ? O PHE B 469 
AB4 4 5 O LYS B 470 ? O LYS B 470 N GLU B 462 ? N GLU B 462 
AB5 1 2 N THR B 26  ? N THR B 26  O VAL B 38  ? O VAL B 38  
AB6 1 2 N THR B 42  ? N THR B 42  O LEU B 318 ? O LEU B 318 
AB7 1 2 N GLN B 46  ? N GLN B 46  O PHE B 296 ? O PHE B 296 
AB7 2 3 N GLN B 297 ? N GLN B 297 O LYS B 309 ? O LYS B 309 
AB8 1 2 N ILE B 53  ? N ILE B 53  O GLU B 277 ? O GLU B 277 
AB9 1 2 N LEU B 61  ? N LEU B 61  O VAL B 90  ? O VAL B 90  
AB9 2 3 N PHE B 89  ? N PHE B 89  O MET B 270 ? O MET B 270 
AC1 1 2 N ASP B 103 ? N ASP B 103 O ILE B 232 ? O ILE B 232 
AC1 2 3 O THR B 237 ? O THR B 237 N TYR B 180 ? N TYR B 180 
AC1 3 4 N LEU B 179 ? N LEU B 179 O PHE B 260 ? O PHE B 260 
AC1 4 5 O PHE B 259 ? O PHE B 259 N ILE B 123 ? N ILE B 123 
AC2 1 2 N ASP B 103 ? N ASP B 103 O ILE B 232 ? O ILE B 232 
AC2 2 3 O THR B 237 ? O THR B 237 N TYR B 180 ? N TYR B 180 
AC2 3 4 N GLY B 183 ? N GLY B 183 O ILE B 254 ? O ILE B 254 
AC2 4 5 O ALA B 255 ? O ALA B 255 N ASN B 154 ? N ASN B 154 
AC3 1 2 N SER B 133 ? N SER B 133 O THR B 157 ? O THR B 157 
AC4 1 2 N CYS B 141 ? N CYS B 141 O GLY B 148 ? O GLY B 148 
AC5 1 2 N LEU B 166 ? N LEU B 166 O SER B 249 ? O SER B 249 
AC5 2 3 O ASN B 248 ? O ASN B 248 N THR B 205 ? N THR B 205 
AC5 3 4 N VAL B 204 ? N VAL B 204 O ILE B 215 ? O ILE B 215 
AC6 1 2 O ILE B 290 ? O ILE B 290 N CYS B 283 ? N CYS B 283 
AC6 2 3 N ILE B 284 ? N ILE B 284 O TYR B 304 ? O TYR B 304 
AC6 3 4 N GLY B 305 ? N GLY B 305 O LYS B 393 ? O LYS B 393 
AC7 1 2 O GLY C 364 ? O GLY C 364 N HIS C 357 ? N HIS C 357 
AC7 2 3 O ARG C 356 ? O ARG C 356 N CYS C 16  ? N CYS C 16  
AC7 3 4 N LEU C 15  ? N LEU C 15  O PHE C 469 ? O PHE C 469 
AC7 4 5 O LYS C 470 ? O LYS C 470 N GLU C 462 ? N GLU C 462 
AC8 1 2 N THR C 26  ? N THR C 26  O VAL C 38  ? O VAL C 38  
AC9 1 2 N THR C 42  ? N THR C 42  O LEU C 318 ? O LEU C 318 
AD1 1 2 N GLN C 46  ? N GLN C 46  O PHE C 296 ? O PHE C 296 
AD1 2 3 N GLN C 297 ? N GLN C 297 O LYS C 309 ? O LYS C 309 
AD2 1 2 N ILE C 53  ? N ILE C 53  O GLU C 277 ? O GLU C 277 
AD3 1 2 N LEU C 61  ? N LEU C 61  O VAL C 90  ? O VAL C 90  
AD3 2 3 N GLU C 91  ? N GLU C 91  O MET C 270 ? O MET C 270 
AD4 1 2 N ASP C 103 ? N ASP C 103 O ILE C 232 ? O ILE C 232 
AD4 2 3 O ARG C 231 ? O ARG C 231 N HIS C 186 ? N HIS C 186 
AD4 3 4 N LEU C 179 ? N LEU C 179 O PHE C 260 ? O PHE C 260 
AD4 4 5 O PHE C 259 ? O PHE C 259 N ILE C 123 ? N ILE C 123 
AD5 1 2 N ASP C 103 ? N ASP C 103 O ILE C 232 ? O ILE C 232 
AD5 2 3 O ARG C 231 ? O ARG C 231 N HIS C 186 ? N HIS C 186 
AD5 3 4 N GLY C 183 ? N GLY C 183 O ILE C 254 ? O ILE C 254 
AD5 4 5 O ALA C 255 ? O ALA C 255 N ASN C 154 ? N ASN C 154 
AD6 1 2 N SER C 133 ? N SER C 133 O THR C 157 ? O THR C 157 
AD7 1 2 N ARG C 143 ? N ARG C 143 O ALA C 146 ? O ALA C 146 
AD8 1 2 N LEU C 166 ? N LEU C 166 O SER C 249 ? O SER C 249 
AD8 2 3 O ASN C 248 ? O ASN C 248 N THR C 205 ? N THR C 205 
AD8 3 4 N VAL C 204 ? N VAL C 204 O ILE C 215 ? O ILE C 215 
AD9 1 2 O ILE C 290 ? O ILE C 290 N CYS C 283 ? N CYS C 283 
AD9 2 3 N ILE C 284 ? N ILE C 284 O TYR C 304 ? O TYR C 304 
AD9 3 4 N GLY C 305 ? N GLY C 305 O LYS C 393 ? O LYS C 393 
# 
_pdbx_entry_details.entry_id                   8ZW5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ARG B 64 ? ? 56.22 -112.32 
2 1 ARG C 64 ? ? 56.12 -111.06 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZW5 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8ZW5 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.09 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               279549 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'HN/4-10 H3N8 G228 HA complexed with LSTa' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8ZW5 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8ZW5 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZW5 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A LEU 1   ? A LEU 1   
2  1 Y 1 A GLN 2   ? A GLN 2   
3  1 Y 1 A GLN 3   ? A GLN 3   
4  1 Y 1 A ASN 4   ? A ASN 4   
5  1 Y 1 A LEU 5   ? A LEU 5   
6  1 Y 1 A PRO 6   ? A PRO 6   
7  1 Y 1 A GLY 7   ? A GLY 7   
8  1 Y 1 A LYS 8   ? A LYS 8   
9  1 Y 1 A ASP 9   ? A ASP 9   
10 1 Y 1 A SER 10  ? A SER 10  
11 1 Y 1 A SER 11  ? A SER 11  
12 1 Y 1 A LYS 328 ? A LYS 328 
13 1 Y 1 A GLN 329 ? A GLN 329 
14 1 Y 1 A THR 330 ? A THR 330 
15 1 Y 1 A ARG 331 ? A ARG 331 
16 1 Y 1 A GLY 332 ? A GLY 332 
17 1 Y 1 A LEU 333 ? A LEU 333 
18 1 Y 1 A PHE 334 ? A PHE 334 
19 1 Y 1 A GLY 335 ? A GLY 335 
20 1 Y 1 A ALA 336 ? A ALA 336 
21 1 Y 1 A GLN 503 ? A GLN 503 
22 1 Y 1 A ILE 504 ? A ILE 504 
23 1 Y 1 A ARG 505 ? A ARG 505 
24 1 Y 1 A GLY 506 ? A GLY 506 
25 1 Y 1 A VAL 507 ? A VAL 507 
26 1 Y 1 A GLU 508 ? A GLU 508 
27 1 Y 1 A PHE 509 ? A PHE 509 
28 1 Y 1 B LEU 1   ? B LEU 1   
29 1 Y 1 B GLN 2   ? B GLN 2   
30 1 Y 1 B GLN 3   ? B GLN 3   
31 1 Y 1 B ASN 4   ? B ASN 4   
32 1 Y 1 B LEU 5   ? B LEU 5   
33 1 Y 1 B PRO 6   ? B PRO 6   
34 1 Y 1 B GLY 7   ? B GLY 7   
35 1 Y 1 B LYS 8   ? B LYS 8   
36 1 Y 1 B ASP 9   ? B ASP 9   
37 1 Y 1 B SER 10  ? B SER 10  
38 1 Y 1 B SER 11  ? B SER 11  
39 1 Y 1 B GLN 329 ? B GLN 329 
40 1 Y 1 B THR 330 ? B THR 330 
41 1 Y 1 B ARG 331 ? B ARG 331 
42 1 Y 1 B GLY 332 ? B GLY 332 
43 1 Y 1 B LEU 333 ? B LEU 333 
44 1 Y 1 B PHE 334 ? B PHE 334 
45 1 Y 1 B GLY 335 ? B GLY 335 
46 1 Y 1 B GLN 503 ? B GLN 503 
47 1 Y 1 B ILE 504 ? B ILE 504 
48 1 Y 1 B ARG 505 ? B ARG 505 
49 1 Y 1 B GLY 506 ? B GLY 506 
50 1 Y 1 B VAL 507 ? B VAL 507 
51 1 Y 1 B GLU 508 ? B GLU 508 
52 1 Y 1 B PHE 509 ? B PHE 509 
53 1 Y 1 C LEU 1   ? C LEU 1   
54 1 Y 1 C GLN 2   ? C GLN 2   
55 1 Y 1 C GLN 3   ? C GLN 3   
56 1 Y 1 C ASN 4   ? C ASN 4   
57 1 Y 1 C LEU 5   ? C LEU 5   
58 1 Y 1 C PRO 6   ? C PRO 6   
59 1 Y 1 C GLY 7   ? C GLY 7   
60 1 Y 1 C LYS 8   ? C LYS 8   
61 1 Y 1 C ASP 9   ? C ASP 9   
62 1 Y 1 C SER 10  ? C SER 10  
63 1 Y 1 C SER 11  ? C SER 11  
64 1 Y 1 C LYS 328 ? C LYS 328 
65 1 Y 1 C GLN 329 ? C GLN 329 
66 1 Y 1 C THR 330 ? C THR 330 
67 1 Y 1 C ARG 331 ? C ARG 331 
68 1 Y 1 C GLY 332 ? C GLY 332 
69 1 Y 1 C LEU 333 ? C LEU 333 
70 1 Y 1 C PHE 334 ? C PHE 334 
71 1 Y 1 C GLY 335 ? C GLY 335 
72 1 Y 1 C ALA 336 ? C ALA 336 
73 1 Y 1 C GLN 503 ? C GLN 503 
74 1 Y 1 C ILE 504 ? C ILE 504 
75 1 Y 1 C ARG 505 ? C ARG 505 
76 1 Y 1 C GLY 506 ? C GLY 506 
77 1 Y 1 C VAL 507 ? C VAL 507 
78 1 Y 1 C GLU 508 ? C GLU 508 
79 1 Y 1 C PHE 509 ? C PHE 509 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GAL C1   C N R 112 
GAL C2   C N R 113 
GAL C3   C N S 114 
GAL C4   C N R 115 
GAL C5   C N R 116 
GAL C6   C N N 117 
GAL O1   O N N 118 
GAL O2   O N N 119 
GAL O3   O N N 120 
GAL O4   O N N 121 
GAL O5   O N N 122 
GAL O6   O N N 123 
GAL H1   H N N 124 
GAL H2   H N N 125 
GAL H3   H N N 126 
GAL H4   H N N 127 
GAL H5   H N N 128 
GAL H61  H N N 129 
GAL H62  H N N 130 
GAL HO1  H N N 131 
GAL HO2  H N N 132 
GAL HO3  H N N 133 
GAL HO4  H N N 134 
GAL HO6  H N N 135 
GLN N    N N N 136 
GLN CA   C N S 137 
GLN C    C N N 138 
GLN O    O N N 139 
GLN CB   C N N 140 
GLN CG   C N N 141 
GLN CD   C N N 142 
GLN OE1  O N N 143 
GLN NE2  N N N 144 
GLN OXT  O N N 145 
GLN H    H N N 146 
GLN H2   H N N 147 
GLN HA   H N N 148 
GLN HB2  H N N 149 
GLN HB3  H N N 150 
GLN HG2  H N N 151 
GLN HG3  H N N 152 
GLN HE21 H N N 153 
GLN HE22 H N N 154 
GLN HXT  H N N 155 
GLU N    N N N 156 
GLU CA   C N S 157 
GLU C    C N N 158 
GLU O    O N N 159 
GLU CB   C N N 160 
GLU CG   C N N 161 
GLU CD   C N N 162 
GLU OE1  O N N 163 
GLU OE2  O N N 164 
GLU OXT  O N N 165 
GLU H    H N N 166 
GLU H2   H N N 167 
GLU HA   H N N 168 
GLU HB2  H N N 169 
GLU HB3  H N N 170 
GLU HG2  H N N 171 
GLU HG3  H N N 172 
GLU HE2  H N N 173 
GLU HXT  H N N 174 
GLY N    N N N 175 
GLY CA   C N N 176 
GLY C    C N N 177 
GLY O    O N N 178 
GLY OXT  O N N 179 
GLY H    H N N 180 
GLY H2   H N N 181 
GLY HA2  H N N 182 
GLY HA3  H N N 183 
GLY HXT  H N N 184 
HIS N    N N N 185 
HIS CA   C N S 186 
HIS C    C N N 187 
HIS O    O N N 188 
HIS CB   C N N 189 
HIS CG   C Y N 190 
HIS ND1  N Y N 191 
HIS CD2  C Y N 192 
HIS CE1  C Y N 193 
HIS NE2  N Y N 194 
HIS OXT  O N N 195 
HIS H    H N N 196 
HIS H2   H N N 197 
HIS HA   H N N 198 
HIS HB2  H N N 199 
HIS HB3  H N N 200 
HIS HD1  H N N 201 
HIS HD2  H N N 202 
HIS HE1  H N N 203 
HIS HE2  H N N 204 
HIS HXT  H N N 205 
ILE N    N N N 206 
ILE CA   C N S 207 
ILE C    C N N 208 
ILE O    O N N 209 
ILE CB   C N S 210 
ILE CG1  C N N 211 
ILE CG2  C N N 212 
ILE CD1  C N N 213 
ILE OXT  O N N 214 
ILE H    H N N 215 
ILE H2   H N N 216 
ILE HA   H N N 217 
ILE HB   H N N 218 
ILE HG12 H N N 219 
ILE HG13 H N N 220 
ILE HG21 H N N 221 
ILE HG22 H N N 222 
ILE HG23 H N N 223 
ILE HD11 H N N 224 
ILE HD12 H N N 225 
ILE HD13 H N N 226 
ILE HXT  H N N 227 
LEU N    N N N 228 
LEU CA   C N S 229 
LEU C    C N N 230 
LEU O    O N N 231 
LEU CB   C N N 232 
LEU CG   C N N 233 
LEU CD1  C N N 234 
LEU CD2  C N N 235 
LEU OXT  O N N 236 
LEU H    H N N 237 
LEU H2   H N N 238 
LEU HA   H N N 239 
LEU HB2  H N N 240 
LEU HB3  H N N 241 
LEU HG   H N N 242 
LEU HD11 H N N 243 
LEU HD12 H N N 244 
LEU HD13 H N N 245 
LEU HD21 H N N 246 
LEU HD22 H N N 247 
LEU HD23 H N N 248 
LEU HXT  H N N 249 
LYS N    N N N 250 
LYS CA   C N S 251 
LYS C    C N N 252 
LYS O    O N N 253 
LYS CB   C N N 254 
LYS CG   C N N 255 
LYS CD   C N N 256 
LYS CE   C N N 257 
LYS NZ   N N N 258 
LYS OXT  O N N 259 
LYS H    H N N 260 
LYS H2   H N N 261 
LYS HA   H N N 262 
LYS HB2  H N N 263 
LYS HB3  H N N 264 
LYS HG2  H N N 265 
LYS HG3  H N N 266 
LYS HD2  H N N 267 
LYS HD3  H N N 268 
LYS HE2  H N N 269 
LYS HE3  H N N 270 
LYS HZ1  H N N 271 
LYS HZ2  H N N 272 
LYS HZ3  H N N 273 
LYS HXT  H N N 274 
MAN C1   C N S 275 
MAN C2   C N S 276 
MAN C3   C N S 277 
MAN C4   C N S 278 
MAN C5   C N R 279 
MAN C6   C N N 280 
MAN O1   O N N 281 
MAN O2   O N N 282 
MAN O3   O N N 283 
MAN O4   O N N 284 
MAN O5   O N N 285 
MAN O6   O N N 286 
MAN H1   H N N 287 
MAN H2   H N N 288 
MAN H3   H N N 289 
MAN H4   H N N 290 
MAN H5   H N N 291 
MAN H61  H N N 292 
MAN H62  H N N 293 
MAN HO1  H N N 294 
MAN HO2  H N N 295 
MAN HO3  H N N 296 
MAN HO4  H N N 297 
MAN HO6  H N N 298 
MET N    N N N 299 
MET CA   C N S 300 
MET C    C N N 301 
MET O    O N N 302 
MET CB   C N N 303 
MET CG   C N N 304 
MET SD   S N N 305 
MET CE   C N N 306 
MET OXT  O N N 307 
MET H    H N N 308 
MET H2   H N N 309 
MET HA   H N N 310 
MET HB2  H N N 311 
MET HB3  H N N 312 
MET HG2  H N N 313 
MET HG3  H N N 314 
MET HE1  H N N 315 
MET HE2  H N N 316 
MET HE3  H N N 317 
MET HXT  H N N 318 
NAG C1   C N R 319 
NAG C2   C N R 320 
NAG C3   C N R 321 
NAG C4   C N S 322 
NAG C5   C N R 323 
NAG C6   C N N 324 
NAG C7   C N N 325 
NAG C8   C N N 326 
NAG N2   N N N 327 
NAG O1   O N N 328 
NAG O3   O N N 329 
NAG O4   O N N 330 
NAG O5   O N N 331 
NAG O6   O N N 332 
NAG O7   O N N 333 
NAG H1   H N N 334 
NAG H2   H N N 335 
NAG H3   H N N 336 
NAG H4   H N N 337 
NAG H5   H N N 338 
NAG H61  H N N 339 
NAG H62  H N N 340 
NAG H81  H N N 341 
NAG H82  H N N 342 
NAG H83  H N N 343 
NAG HN2  H N N 344 
NAG HO1  H N N 345 
NAG HO3  H N N 346 
NAG HO4  H N N 347 
NAG HO6  H N N 348 
PHE N    N N N 349 
PHE CA   C N S 350 
PHE C    C N N 351 
PHE O    O N N 352 
PHE CB   C N N 353 
PHE CG   C Y N 354 
PHE CD1  C Y N 355 
PHE CD2  C Y N 356 
PHE CE1  C Y N 357 
PHE CE2  C Y N 358 
PHE CZ   C Y N 359 
PHE OXT  O N N 360 
PHE H    H N N 361 
PHE H2   H N N 362 
PHE HA   H N N 363 
PHE HB2  H N N 364 
PHE HB3  H N N 365 
PHE HD1  H N N 366 
PHE HD2  H N N 367 
PHE HE1  H N N 368 
PHE HE2  H N N 369 
PHE HZ   H N N 370 
PHE HXT  H N N 371 
PRO N    N N N 372 
PRO CA   C N S 373 
PRO C    C N N 374 
PRO O    O N N 375 
PRO CB   C N N 376 
PRO CG   C N N 377 
PRO CD   C N N 378 
PRO OXT  O N N 379 
PRO H    H N N 380 
PRO HA   H N N 381 
PRO HB2  H N N 382 
PRO HB3  H N N 383 
PRO HG2  H N N 384 
PRO HG3  H N N 385 
PRO HD2  H N N 386 
PRO HD3  H N N 387 
PRO HXT  H N N 388 
SER N    N N N 389 
SER CA   C N S 390 
SER C    C N N 391 
SER O    O N N 392 
SER CB   C N N 393 
SER OG   O N N 394 
SER OXT  O N N 395 
SER H    H N N 396 
SER H2   H N N 397 
SER HA   H N N 398 
SER HB2  H N N 399 
SER HB3  H N N 400 
SER HG   H N N 401 
SER HXT  H N N 402 
SIA C1   C N N 403 
SIA C2   C N R 404 
SIA C3   C N N 405 
SIA C4   C N S 406 
SIA C5   C N R 407 
SIA C6   C N R 408 
SIA C7   C N R 409 
SIA C8   C N R 410 
SIA C9   C N N 411 
SIA C10  C N N 412 
SIA C11  C N N 413 
SIA N5   N N N 414 
SIA O1A  O N N 415 
SIA O1B  O N N 416 
SIA O2   O N N 417 
SIA O4   O N N 418 
SIA O6   O N N 419 
SIA O7   O N N 420 
SIA O8   O N N 421 
SIA O9   O N N 422 
SIA O10  O N N 423 
SIA H32  H N N 424 
SIA H31  H N N 425 
SIA H4   H N N 426 
SIA H5   H N N 427 
SIA H6   H N N 428 
SIA H7   H N N 429 
SIA H8   H N N 430 
SIA H92  H N N 431 
SIA H91  H N N 432 
SIA H111 H N N 433 
SIA H113 H N N 434 
SIA H112 H N N 435 
SIA HN5  H N N 436 
SIA HO1B H N N 437 
SIA HO2  H N N 438 
SIA HO4  H N N 439 
SIA HO7  H N N 440 
SIA HO8  H N N 441 
SIA HO9  H N N 442 
THR N    N N N 443 
THR CA   C N S 444 
THR C    C N N 445 
THR O    O N N 446 
THR CB   C N R 447 
THR OG1  O N N 448 
THR CG2  C N N 449 
THR OXT  O N N 450 
THR H    H N N 451 
THR H2   H N N 452 
THR HA   H N N 453 
THR HB   H N N 454 
THR HG1  H N N 455 
THR HG21 H N N 456 
THR HG22 H N N 457 
THR HG23 H N N 458 
THR HXT  H N N 459 
TRP N    N N N 460 
TRP CA   C N S 461 
TRP C    C N N 462 
TRP O    O N N 463 
TRP CB   C N N 464 
TRP CG   C Y N 465 
TRP CD1  C Y N 466 
TRP CD2  C Y N 467 
TRP NE1  N Y N 468 
TRP CE2  C Y N 469 
TRP CE3  C Y N 470 
TRP CZ2  C Y N 471 
TRP CZ3  C Y N 472 
TRP CH2  C Y N 473 
TRP OXT  O N N 474 
TRP H    H N N 475 
TRP H2   H N N 476 
TRP HA   H N N 477 
TRP HB2  H N N 478 
TRP HB3  H N N 479 
TRP HD1  H N N 480 
TRP HE1  H N N 481 
TRP HE3  H N N 482 
TRP HZ2  H N N 483 
TRP HZ3  H N N 484 
TRP HH2  H N N 485 
TRP HXT  H N N 486 
TYR N    N N N 487 
TYR CA   C N S 488 
TYR C    C N N 489 
TYR O    O N N 490 
TYR CB   C N N 491 
TYR CG   C Y N 492 
TYR CD1  C Y N 493 
TYR CD2  C Y N 494 
TYR CE1  C Y N 495 
TYR CE2  C Y N 496 
TYR CZ   C Y N 497 
TYR OH   O N N 498 
TYR OXT  O N N 499 
TYR H    H N N 500 
TYR H2   H N N 501 
TYR HA   H N N 502 
TYR HB2  H N N 503 
TYR HB3  H N N 504 
TYR HD1  H N N 505 
TYR HD2  H N N 506 
TYR HE1  H N N 507 
TYR HE2  H N N 508 
TYR HH   H N N 509 
TYR HXT  H N N 510 
VAL N    N N N 511 
VAL CA   C N S 512 
VAL C    C N N 513 
VAL O    O N N 514 
VAL CB   C N N 515 
VAL CG1  C N N 516 
VAL CG2  C N N 517 
VAL OXT  O N N 518 
VAL H    H N N 519 
VAL H2   H N N 520 
VAL HA   H N N 521 
VAL HB   H N N 522 
VAL HG11 H N N 523 
VAL HG12 H N N 524 
VAL HG13 H N N 525 
VAL HG21 H N N 526 
VAL HG22 H N N 527 
VAL HG23 H N N 528 
VAL HXT  H N N 529 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GAL C1  C2   sing N N 107 
GAL C1  O1   sing N N 108 
GAL C1  O5   sing N N 109 
GAL C1  H1   sing N N 110 
GAL C2  C3   sing N N 111 
GAL C2  O2   sing N N 112 
GAL C2  H2   sing N N 113 
GAL C3  C4   sing N N 114 
GAL C3  O3   sing N N 115 
GAL C3  H3   sing N N 116 
GAL C4  C5   sing N N 117 
GAL C4  O4   sing N N 118 
GAL C4  H4   sing N N 119 
GAL C5  C6   sing N N 120 
GAL C5  O5   sing N N 121 
GAL C5  H5   sing N N 122 
GAL C6  O6   sing N N 123 
GAL C6  H61  sing N N 124 
GAL C6  H62  sing N N 125 
GAL O1  HO1  sing N N 126 
GAL O2  HO2  sing N N 127 
GAL O3  HO3  sing N N 128 
GAL O4  HO4  sing N N 129 
GAL O6  HO6  sing N N 130 
GLN N   CA   sing N N 131 
GLN N   H    sing N N 132 
GLN N   H2   sing N N 133 
GLN CA  C    sing N N 134 
GLN CA  CB   sing N N 135 
GLN CA  HA   sing N N 136 
GLN C   O    doub N N 137 
GLN C   OXT  sing N N 138 
GLN CB  CG   sing N N 139 
GLN CB  HB2  sing N N 140 
GLN CB  HB3  sing N N 141 
GLN CG  CD   sing N N 142 
GLN CG  HG2  sing N N 143 
GLN CG  HG3  sing N N 144 
GLN CD  OE1  doub N N 145 
GLN CD  NE2  sing N N 146 
GLN NE2 HE21 sing N N 147 
GLN NE2 HE22 sing N N 148 
GLN OXT HXT  sing N N 149 
GLU N   CA   sing N N 150 
GLU N   H    sing N N 151 
GLU N   H2   sing N N 152 
GLU CA  C    sing N N 153 
GLU CA  CB   sing N N 154 
GLU CA  HA   sing N N 155 
GLU C   O    doub N N 156 
GLU C   OXT  sing N N 157 
GLU CB  CG   sing N N 158 
GLU CB  HB2  sing N N 159 
GLU CB  HB3  sing N N 160 
GLU CG  CD   sing N N 161 
GLU CG  HG2  sing N N 162 
GLU CG  HG3  sing N N 163 
GLU CD  OE1  doub N N 164 
GLU CD  OE2  sing N N 165 
GLU OE2 HE2  sing N N 166 
GLU OXT HXT  sing N N 167 
GLY N   CA   sing N N 168 
GLY N   H    sing N N 169 
GLY N   H2   sing N N 170 
GLY CA  C    sing N N 171 
GLY CA  HA2  sing N N 172 
GLY CA  HA3  sing N N 173 
GLY C   O    doub N N 174 
GLY C   OXT  sing N N 175 
GLY OXT HXT  sing N N 176 
HIS N   CA   sing N N 177 
HIS N   H    sing N N 178 
HIS N   H2   sing N N 179 
HIS CA  C    sing N N 180 
HIS CA  CB   sing N N 181 
HIS CA  HA   sing N N 182 
HIS C   O    doub N N 183 
HIS C   OXT  sing N N 184 
HIS CB  CG   sing N N 185 
HIS CB  HB2  sing N N 186 
HIS CB  HB3  sing N N 187 
HIS CG  ND1  sing Y N 188 
HIS CG  CD2  doub Y N 189 
HIS ND1 CE1  doub Y N 190 
HIS ND1 HD1  sing N N 191 
HIS CD2 NE2  sing Y N 192 
HIS CD2 HD2  sing N N 193 
HIS CE1 NE2  sing Y N 194 
HIS CE1 HE1  sing N N 195 
HIS NE2 HE2  sing N N 196 
HIS OXT HXT  sing N N 197 
ILE N   CA   sing N N 198 
ILE N   H    sing N N 199 
ILE N   H2   sing N N 200 
ILE CA  C    sing N N 201 
ILE CA  CB   sing N N 202 
ILE CA  HA   sing N N 203 
ILE C   O    doub N N 204 
ILE C   OXT  sing N N 205 
ILE CB  CG1  sing N N 206 
ILE CB  CG2  sing N N 207 
ILE CB  HB   sing N N 208 
ILE CG1 CD1  sing N N 209 
ILE CG1 HG12 sing N N 210 
ILE CG1 HG13 sing N N 211 
ILE CG2 HG21 sing N N 212 
ILE CG2 HG22 sing N N 213 
ILE CG2 HG23 sing N N 214 
ILE CD1 HD11 sing N N 215 
ILE CD1 HD12 sing N N 216 
ILE CD1 HD13 sing N N 217 
ILE OXT HXT  sing N N 218 
LEU N   CA   sing N N 219 
LEU N   H    sing N N 220 
LEU N   H2   sing N N 221 
LEU CA  C    sing N N 222 
LEU CA  CB   sing N N 223 
LEU CA  HA   sing N N 224 
LEU C   O    doub N N 225 
LEU C   OXT  sing N N 226 
LEU CB  CG   sing N N 227 
LEU CB  HB2  sing N N 228 
LEU CB  HB3  sing N N 229 
LEU CG  CD1  sing N N 230 
LEU CG  CD2  sing N N 231 
LEU CG  HG   sing N N 232 
LEU CD1 HD11 sing N N 233 
LEU CD1 HD12 sing N N 234 
LEU CD1 HD13 sing N N 235 
LEU CD2 HD21 sing N N 236 
LEU CD2 HD22 sing N N 237 
LEU CD2 HD23 sing N N 238 
LEU OXT HXT  sing N N 239 
LYS N   CA   sing N N 240 
LYS N   H    sing N N 241 
LYS N   H2   sing N N 242 
LYS CA  C    sing N N 243 
LYS CA  CB   sing N N 244 
LYS CA  HA   sing N N 245 
LYS C   O    doub N N 246 
LYS C   OXT  sing N N 247 
LYS CB  CG   sing N N 248 
LYS CB  HB2  sing N N 249 
LYS CB  HB3  sing N N 250 
LYS CG  CD   sing N N 251 
LYS CG  HG2  sing N N 252 
LYS CG  HG3  sing N N 253 
LYS CD  CE   sing N N 254 
LYS CD  HD2  sing N N 255 
LYS CD  HD3  sing N N 256 
LYS CE  NZ   sing N N 257 
LYS CE  HE2  sing N N 258 
LYS CE  HE3  sing N N 259 
LYS NZ  HZ1  sing N N 260 
LYS NZ  HZ2  sing N N 261 
LYS NZ  HZ3  sing N N 262 
LYS OXT HXT  sing N N 263 
MAN C1  C2   sing N N 264 
MAN C1  O1   sing N N 265 
MAN C1  O5   sing N N 266 
MAN C1  H1   sing N N 267 
MAN C2  C3   sing N N 268 
MAN C2  O2   sing N N 269 
MAN C2  H2   sing N N 270 
MAN C3  C4   sing N N 271 
MAN C3  O3   sing N N 272 
MAN C3  H3   sing N N 273 
MAN C4  C5   sing N N 274 
MAN C4  O4   sing N N 275 
MAN C4  H4   sing N N 276 
MAN C5  C6   sing N N 277 
MAN C5  O5   sing N N 278 
MAN C5  H5   sing N N 279 
MAN C6  O6   sing N N 280 
MAN C6  H61  sing N N 281 
MAN C6  H62  sing N N 282 
MAN O1  HO1  sing N N 283 
MAN O2  HO2  sing N N 284 
MAN O3  HO3  sing N N 285 
MAN O4  HO4  sing N N 286 
MAN O6  HO6  sing N N 287 
MET N   CA   sing N N 288 
MET N   H    sing N N 289 
MET N   H2   sing N N 290 
MET CA  C    sing N N 291 
MET CA  CB   sing N N 292 
MET CA  HA   sing N N 293 
MET C   O    doub N N 294 
MET C   OXT  sing N N 295 
MET CB  CG   sing N N 296 
MET CB  HB2  sing N N 297 
MET CB  HB3  sing N N 298 
MET CG  SD   sing N N 299 
MET CG  HG2  sing N N 300 
MET CG  HG3  sing N N 301 
MET SD  CE   sing N N 302 
MET CE  HE1  sing N N 303 
MET CE  HE2  sing N N 304 
MET CE  HE3  sing N N 305 
MET OXT HXT  sing N N 306 
NAG C1  C2   sing N N 307 
NAG C1  O1   sing N N 308 
NAG C1  O5   sing N N 309 
NAG C1  H1   sing N N 310 
NAG C2  C3   sing N N 311 
NAG C2  N2   sing N N 312 
NAG C2  H2   sing N N 313 
NAG C3  C4   sing N N 314 
NAG C3  O3   sing N N 315 
NAG C3  H3   sing N N 316 
NAG C4  C5   sing N N 317 
NAG C4  O4   sing N N 318 
NAG C4  H4   sing N N 319 
NAG C5  C6   sing N N 320 
NAG C5  O5   sing N N 321 
NAG C5  H5   sing N N 322 
NAG C6  O6   sing N N 323 
NAG C6  H61  sing N N 324 
NAG C6  H62  sing N N 325 
NAG C7  C8   sing N N 326 
NAG C7  N2   sing N N 327 
NAG C7  O7   doub N N 328 
NAG C8  H81  sing N N 329 
NAG C8  H82  sing N N 330 
NAG C8  H83  sing N N 331 
NAG N2  HN2  sing N N 332 
NAG O1  HO1  sing N N 333 
NAG O3  HO3  sing N N 334 
NAG O4  HO4  sing N N 335 
NAG O6  HO6  sing N N 336 
PHE N   CA   sing N N 337 
PHE N   H    sing N N 338 
PHE N   H2   sing N N 339 
PHE CA  C    sing N N 340 
PHE CA  CB   sing N N 341 
PHE CA  HA   sing N N 342 
PHE C   O    doub N N 343 
PHE C   OXT  sing N N 344 
PHE CB  CG   sing N N 345 
PHE CB  HB2  sing N N 346 
PHE CB  HB3  sing N N 347 
PHE CG  CD1  doub Y N 348 
PHE CG  CD2  sing Y N 349 
PHE CD1 CE1  sing Y N 350 
PHE CD1 HD1  sing N N 351 
PHE CD2 CE2  doub Y N 352 
PHE CD2 HD2  sing N N 353 
PHE CE1 CZ   doub Y N 354 
PHE CE1 HE1  sing N N 355 
PHE CE2 CZ   sing Y N 356 
PHE CE2 HE2  sing N N 357 
PHE CZ  HZ   sing N N 358 
PHE OXT HXT  sing N N 359 
PRO N   CA   sing N N 360 
PRO N   CD   sing N N 361 
PRO N   H    sing N N 362 
PRO CA  C    sing N N 363 
PRO CA  CB   sing N N 364 
PRO CA  HA   sing N N 365 
PRO C   O    doub N N 366 
PRO C   OXT  sing N N 367 
PRO CB  CG   sing N N 368 
PRO CB  HB2  sing N N 369 
PRO CB  HB3  sing N N 370 
PRO CG  CD   sing N N 371 
PRO CG  HG2  sing N N 372 
PRO CG  HG3  sing N N 373 
PRO CD  HD2  sing N N 374 
PRO CD  HD3  sing N N 375 
PRO OXT HXT  sing N N 376 
SER N   CA   sing N N 377 
SER N   H    sing N N 378 
SER N   H2   sing N N 379 
SER CA  C    sing N N 380 
SER CA  CB   sing N N 381 
SER CA  HA   sing N N 382 
SER C   O    doub N N 383 
SER C   OXT  sing N N 384 
SER CB  OG   sing N N 385 
SER CB  HB2  sing N N 386 
SER CB  HB3  sing N N 387 
SER OG  HG   sing N N 388 
SER OXT HXT  sing N N 389 
SIA C1  C2   sing N N 390 
SIA C1  O1A  doub N N 391 
SIA C1  O1B  sing N N 392 
SIA C2  C3   sing N N 393 
SIA C2  O2   sing N N 394 
SIA C2  O6   sing N N 395 
SIA C3  C4   sing N N 396 
SIA C3  H32  sing N N 397 
SIA C3  H31  sing N N 398 
SIA C4  C5   sing N N 399 
SIA C4  O4   sing N N 400 
SIA C4  H4   sing N N 401 
SIA C5  C6   sing N N 402 
SIA C5  N5   sing N N 403 
SIA C5  H5   sing N N 404 
SIA C6  C7   sing N N 405 
SIA C6  O6   sing N N 406 
SIA C6  H6   sing N N 407 
SIA C7  C8   sing N N 408 
SIA C7  O7   sing N N 409 
SIA C7  H7   sing N N 410 
SIA C8  C9   sing N N 411 
SIA C8  O8   sing N N 412 
SIA C8  H8   sing N N 413 
SIA C9  O9   sing N N 414 
SIA C9  H92  sing N N 415 
SIA C9  H91  sing N N 416 
SIA C10 C11  sing N N 417 
SIA C10 N5   sing N N 418 
SIA C10 O10  doub N N 419 
SIA C11 H111 sing N N 420 
SIA C11 H113 sing N N 421 
SIA C11 H112 sing N N 422 
SIA N5  HN5  sing N N 423 
SIA O1B HO1B sing N N 424 
SIA O2  HO2  sing N N 425 
SIA O4  HO4  sing N N 426 
SIA O7  HO7  sing N N 427 
SIA O8  HO8  sing N N 428 
SIA O9  HO9  sing N N 429 
THR N   CA   sing N N 430 
THR N   H    sing N N 431 
THR N   H2   sing N N 432 
THR CA  C    sing N N 433 
THR CA  CB   sing N N 434 
THR CA  HA   sing N N 435 
THR C   O    doub N N 436 
THR C   OXT  sing N N 437 
THR CB  OG1  sing N N 438 
THR CB  CG2  sing N N 439 
THR CB  HB   sing N N 440 
THR OG1 HG1  sing N N 441 
THR CG2 HG21 sing N N 442 
THR CG2 HG22 sing N N 443 
THR CG2 HG23 sing N N 444 
THR OXT HXT  sing N N 445 
TRP N   CA   sing N N 446 
TRP N   H    sing N N 447 
TRP N   H2   sing N N 448 
TRP CA  C    sing N N 449 
TRP CA  CB   sing N N 450 
TRP CA  HA   sing N N 451 
TRP C   O    doub N N 452 
TRP C   OXT  sing N N 453 
TRP CB  CG   sing N N 454 
TRP CB  HB2  sing N N 455 
TRP CB  HB3  sing N N 456 
TRP CG  CD1  doub Y N 457 
TRP CG  CD2  sing Y N 458 
TRP CD1 NE1  sing Y N 459 
TRP CD1 HD1  sing N N 460 
TRP CD2 CE2  doub Y N 461 
TRP CD2 CE3  sing Y N 462 
TRP NE1 CE2  sing Y N 463 
TRP NE1 HE1  sing N N 464 
TRP CE2 CZ2  sing Y N 465 
TRP CE3 CZ3  doub Y N 466 
TRP CE3 HE3  sing N N 467 
TRP CZ2 CH2  doub Y N 468 
TRP CZ2 HZ2  sing N N 469 
TRP CZ3 CH2  sing Y N 470 
TRP CZ3 HZ3  sing N N 471 
TRP CH2 HH2  sing N N 472 
TRP OXT HXT  sing N N 473 
TYR N   CA   sing N N 474 
TYR N   H    sing N N 475 
TYR N   H2   sing N N 476 
TYR CA  C    sing N N 477 
TYR CA  CB   sing N N 478 
TYR CA  HA   sing N N 479 
TYR C   O    doub N N 480 
TYR C   OXT  sing N N 481 
TYR CB  CG   sing N N 482 
TYR CB  HB2  sing N N 483 
TYR CB  HB3  sing N N 484 
TYR CG  CD1  doub Y N 485 
TYR CG  CD2  sing Y N 486 
TYR CD1 CE1  sing Y N 487 
TYR CD1 HD1  sing N N 488 
TYR CD2 CE2  doub Y N 489 
TYR CD2 HD2  sing N N 490 
TYR CE1 CZ   doub Y N 491 
TYR CE1 HE1  sing N N 492 
TYR CE2 CZ   sing Y N 493 
TYR CE2 HE2  sing N N 494 
TYR CZ  OH   sing N N 495 
TYR OH  HH   sing N N 496 
TYR OXT HXT  sing N N 497 
VAL N   CA   sing N N 498 
VAL N   H    sing N N 499 
VAL N   H2   sing N N 500 
VAL CA  C    sing N N 501 
VAL CA  CB   sing N N 502 
VAL CA  HA   sing N N 503 
VAL C   O    doub N N 504 
VAL C   OXT  sing N N 505 
VAL CB  CG1  sing N N 506 
VAL CB  CG2  sing N N 507 
VAL CB  HB   sing N N 508 
VAL CG1 HG11 sing N N 509 
VAL CG1 HG12 sing N N 510 
VAL CG1 HG13 sing N N 511 
VAL CG2 HG21 sing N N 512 
VAL CG2 HG22 sing N N 513 
VAL CG2 HG23 sing N N 514 
VAL OXT HXT  sing N N 515 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-12 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZW5 
_em_admin.last_update        2025-02-19 
_em_admin.map_release_date   2025-02-19 
_em_admin.title              
'Structure of hemagglutinin from HN/4-10 H3N8 influenza virus G228 mutant complexed with avian receptor analog LSTa' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          11320 
_em_entity_assembly_naturalsource.organism             'Influenza A virus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.0 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
2 BMA 3 n 
2 MAN 4 n 
2 MAN 5 n 
3 NAG 1 n 
3 NAG 2 n 
4 GAL 1 n 
4 SIA 2 n 
# 
_atom_sites.entry_id                    8ZW5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . THR A 1 12  ? 147.229 121.617 201.122 1.00 94.32  ? 12  THR A N   1 
ATOM   2     C CA  . THR A 1 12  ? 146.989 122.257 199.835 1.00 94.32  ? 12  THR A CA  1 
ATOM   3     C C   . THR A 1 12  ? 147.331 121.323 198.677 1.00 94.32  ? 12  THR A C   1 
ATOM   4     O O   . THR A 1 12  ? 147.831 120.218 198.884 1.00 94.32  ? 12  THR A O   1 
ATOM   5     C CB  . THR A 1 12  ? 147.806 123.554 199.686 1.00 94.32  ? 12  THR A CB  1 
ATOM   6     O OG1 . THR A 1 12  ? 149.205 123.251 199.750 1.00 94.32  ? 12  THR A OG1 1 
ATOM   7     C CG2 . THR A 1 12  ? 147.452 124.541 200.788 1.00 94.32  ? 12  THR A CG2 1 
ATOM   8     N N   . ALA A 1 13  ? 147.050 121.779 197.459 1.00 92.30  ? 13  ALA A N   1 
ATOM   9     C CA  . ALA A 1 13  ? 147.350 121.023 196.252 1.00 92.30  ? 13  ALA A CA  1 
ATOM   10    C C   . ALA A 1 13  ? 147.376 121.986 195.075 1.00 92.30  ? 13  ALA A C   1 
ATOM   11    O O   . ALA A 1 13  ? 146.858 123.102 195.154 1.00 92.30  ? 13  ALA A O   1 
ATOM   12    C CB  . ALA A 1 13  ? 146.328 119.905 196.016 1.00 92.30  ? 13  ALA A CB  1 
ATOM   13    N N   . THR A 1 14  ? 147.986 121.550 193.975 1.00 87.92  ? 14  THR A N   1 
ATOM   14    C CA  . THR A 1 14  ? 148.063 122.363 192.769 1.00 87.92  ? 14  THR A CA  1 
ATOM   15    C C   . THR A 1 14  ? 147.438 121.614 191.603 1.00 87.92  ? 14  THR A C   1 
ATOM   16    O O   . THR A 1 14  ? 147.667 120.413 191.435 1.00 87.92  ? 14  THR A O   1 
ATOM   17    C CB  . THR A 1 14  ? 149.512 122.731 192.435 1.00 87.92  ? 14  THR A CB  1 
ATOM   18    O OG1 . THR A 1 14  ? 150.221 123.032 193.643 1.00 87.92  ? 14  THR A OG1 1 
ATOM   19    C CG2 . THR A 1 14  ? 149.558 123.938 191.510 1.00 87.92  ? 14  THR A CG2 1 
ATOM   20    N N   . LEU A 1 15  ? 146.653 122.325 190.795 1.00 83.63  ? 15  LEU A N   1 
ATOM   21    C CA  . LEU A 1 15  ? 146.029 121.738 189.611 1.00 83.63  ? 15  LEU A CA  1 
ATOM   22    C C   . LEU A 1 15  ? 146.218 122.693 188.442 1.00 83.63  ? 15  LEU A C   1 
ATOM   23    O O   . LEU A 1 15  ? 145.666 123.794 188.446 1.00 83.63  ? 15  LEU A O   1 
ATOM   24    C CB  . LEU A 1 15  ? 144.546 121.457 189.845 1.00 83.63  ? 15  LEU A CB  1 
ATOM   25    C CG  . LEU A 1 15  ? 143.848 120.716 188.704 1.00 83.63  ? 15  LEU A CG  1 
ATOM   26    C CD1 . LEU A 1 15  ? 144.370 119.293 188.600 1.00 83.63  ? 15  LEU A CD1 1 
ATOM   27    C CD2 . LEU A 1 15  ? 142.346 120.732 188.895 1.00 83.63  ? 15  LEU A CD2 1 
ATOM   28    N N   . CYS A 1 16  ? 146.980 122.275 187.441 1.00 80.10  ? 16  CYS A N   1 
ATOM   29    C CA  . CYS A 1 16  ? 147.275 123.111 186.290 1.00 80.10  ? 16  CYS A CA  1 
ATOM   30    C C   . CYS A 1 16  ? 146.653 122.527 185.028 1.00 80.10  ? 16  CYS A C   1 
ATOM   31    O O   . CYS A 1 16  ? 146.454 121.316 184.913 1.00 80.10  ? 16  CYS A O   1 
ATOM   32    C CB  . CYS A 1 16  ? 148.785 123.261 186.108 1.00 80.10  ? 16  CYS A CB  1 
ATOM   33    S SG  . CYS A 1 16  ? 149.601 124.067 187.497 1.00 80.10  ? 16  CYS A SG  1 
ATOM   34    N N   . LEU A 1 17  ? 146.349 123.407 184.079 1.00 74.95  ? 17  LEU A N   1 
ATOM   35    C CA  . LEU A 1 17  ? 145.783 123.028 182.793 1.00 74.95  ? 17  LEU A CA  1 
ATOM   36    C C   . LEU A 1 17  ? 146.762 123.401 181.691 1.00 74.95  ? 17  LEU A C   1 
ATOM   37    O O   . LEU A 1 17  ? 147.394 124.460 181.748 1.00 74.95  ? 17  LEU A O   1 
ATOM   38    C CB  . LEU A 1 17  ? 144.435 123.716 182.563 1.00 74.95  ? 17  LEU A CB  1 
ATOM   39    C CG  . LEU A 1 17  ? 143.281 123.239 183.447 1.00 74.95  ? 17  LEU A CG  1 
ATOM   40    C CD1 . LEU A 1 17  ? 143.156 124.099 184.696 1.00 74.95  ? 17  LEU A CD1 1 
ATOM   41    C CD2 . LEU A 1 17  ? 141.981 123.237 182.673 1.00 74.95  ? 17  LEU A CD2 1 
ATOM   42    N N   . GLY A 1 18  ? 146.894 122.535 180.689 1.00 70.44  ? 18  GLY A N   1 
ATOM   43    C CA  . GLY A 1 18  ? 147.881 122.799 179.660 1.00 70.44  ? 18  GLY A CA  1 
ATOM   44    C C   . GLY A 1 18  ? 147.527 122.153 178.339 1.00 70.44  ? 18  GLY A C   1 
ATOM   45    O O   . GLY A 1 18  ? 146.560 121.397 178.225 1.00 70.44  ? 18  GLY A O   1 
ATOM   46    N N   . HIS A 1 19  ? 148.343 122.464 177.333 1.00 67.30  ? 19  HIS A N   1 
ATOM   47    C CA  . HIS A 1 19  ? 148.156 121.964 175.980 1.00 67.30  ? 19  HIS A CA  1 
ATOM   48    C C   . HIS A 1 19  ? 149.481 121.446 175.434 1.00 67.30  ? 19  HIS A C   1 
ATOM   49    O O   . HIS A 1 19  ? 150.560 121.872 175.852 1.00 67.30  ? 19  HIS A O   1 
ATOM   50    C CB  . HIS A 1 19  ? 147.580 123.045 175.050 1.00 67.30  ? 19  HIS A CB  1 
ATOM   51    C CG  . HIS A 1 19  ? 148.491 124.214 174.839 1.00 67.30  ? 19  HIS A CG  1 
ATOM   52    N ND1 . HIS A 1 19  ? 148.292 125.432 175.451 1.00 67.30  ? 19  HIS A ND1 1 
ATOM   53    C CD2 . HIS A 1 19  ? 149.603 124.354 174.079 1.00 67.30  ? 19  HIS A CD2 1 
ATOM   54    C CE1 . HIS A 1 19  ? 149.244 126.269 175.082 1.00 67.30  ? 19  HIS A CE1 1 
ATOM   55    N NE2 . HIS A 1 19  ? 150.053 125.640 174.250 1.00 67.30  ? 19  HIS A NE2 1 
ATOM   56    N N   . HIS A 1 20  ? 149.381 120.522 174.483 1.00 66.96  ? 20  HIS A N   1 
ATOM   57    C CA  . HIS A 1 20  ? 150.546 119.815 173.971 1.00 66.96  ? 20  HIS A CA  1 
ATOM   58    C C   . HIS A 1 20  ? 151.403 120.715 173.082 1.00 66.96  ? 20  HIS A C   1 
ATOM   59    O O   . HIS A 1 20  ? 150.962 121.755 172.587 1.00 66.96  ? 20  HIS A O   1 
ATOM   60    C CB  . HIS A 1 20  ? 150.111 118.573 173.193 1.00 66.96  ? 20  HIS A CB  1 
ATOM   61    C CG  . HIS A 1 20  ? 149.594 118.869 171.820 1.00 66.96  ? 20  HIS A CG  1 
ATOM   62    N ND1 . HIS A 1 20  ? 149.938 118.117 170.718 1.00 66.96  ? 20  HIS A ND1 1 
ATOM   63    C CD2 . HIS A 1 20  ? 148.759 119.836 171.370 1.00 66.96  ? 20  HIS A CD2 1 
ATOM   64    C CE1 . HIS A 1 20  ? 149.336 118.607 169.648 1.00 66.96  ? 20  HIS A CE1 1 
ATOM   65    N NE2 . HIS A 1 20  ? 148.616 119.650 170.017 1.00 66.96  ? 20  HIS A NE2 1 
ATOM   66    N N   . SER A 1 21  ? 152.649 120.289 172.882 1.00 66.15  ? 21  SER A N   1 
ATOM   67    C CA  . SER A 1 21  ? 153.615 121.007 172.062 1.00 66.15  ? 21  SER A CA  1 
ATOM   68    C C   . SER A 1 21  ? 154.480 119.999 171.316 1.00 66.15  ? 21  SER A C   1 
ATOM   69    O O   . SER A 1 21  ? 154.576 118.832 171.701 1.00 66.15  ? 21  SER A O   1 
ATOM   70    C CB  . SER A 1 21  ? 154.487 121.939 172.913 1.00 66.15  ? 21  SER A CB  1 
ATOM   71    O OG  . SER A 1 21  ? 155.427 122.633 172.115 1.00 66.15  ? 21  SER A OG  1 
ATOM   72    N N   . VAL A 1 22  ? 155.109 120.457 170.236 1.00 62.38  ? 22  VAL A N   1 
ATOM   73    C CA  . VAL A 1 22  ? 155.953 119.589 169.415 1.00 62.38  ? 22  VAL A CA  1 
ATOM   74    C C   . VAL A 1 22  ? 157.326 120.229 169.236 1.00 62.38  ? 22  VAL A C   1 
ATOM   75    O O   . VAL A 1 22  ? 157.441 121.463 169.259 1.00 62.38  ? 22  VAL A O   1 
ATOM   76    C CB  . VAL A 1 22  ? 155.299 119.292 168.055 1.00 62.38  ? 22  VAL A CB  1 
ATOM   77    C CG1 . VAL A 1 22  ? 154.033 118.468 168.239 1.00 62.38  ? 22  VAL A CG1 1 
ATOM   78    C CG2 . VAL A 1 22  ? 155.003 120.581 167.307 1.00 62.38  ? 22  VAL A CG2 1 
ATOM   79    N N   . PRO A 1 23  ? 158.391 119.438 169.070 1.00 64.14  ? 23  PRO A N   1 
ATOM   80    C CA  . PRO A 1 23  ? 159.730 120.038 168.949 1.00 64.14  ? 23  PRO A CA  1 
ATOM   81    C C   . PRO A 1 23  ? 159.944 120.820 167.664 1.00 64.14  ? 23  PRO A C   1 
ATOM   82    O O   . PRO A 1 23  ? 160.734 121.772 167.665 1.00 64.14  ? 23  PRO A O   1 
ATOM   83    C CB  . PRO A 1 23  ? 160.670 118.826 169.032 1.00 64.14  ? 23  PRO A CB  1 
ATOM   84    C CG  . PRO A 1 23  ? 159.827 117.652 168.677 1.00 64.14  ? 23  PRO A CG  1 
ATOM   85    C CD  . PRO A 1 23  ? 158.442 117.968 169.141 1.00 64.14  ? 23  PRO A CD  1 
ATOM   86    N N   . ASN A 1 24  ? 159.278 120.458 166.570 1.00 62.52  ? 24  ASN A N   1 
ATOM   87    C CA  . ASN A 1 24  ? 159.452 121.134 165.287 1.00 62.52  ? 24  ASN A CA  1 
ATOM   88    C C   . ASN A 1 24  ? 158.086 121.477 164.704 1.00 62.52  ? 24  ASN A C   1 
ATOM   89    O O   . ASN A 1 24  ? 157.341 120.584 164.286 1.00 62.52  ? 24  ASN A O   1 
ATOM   90    C CB  . ASN A 1 24  ? 160.266 120.272 164.320 1.00 62.52  ? 24  ASN A CB  1 
ATOM   91    C CG  . ASN A 1 24  ? 159.749 118.849 164.225 1.00 62.52  ? 24  ASN A CG  1 
ATOM   92    O OD1 . ASN A 1 24  ? 158.940 118.412 165.045 1.00 62.52  ? 24  ASN A OD1 1 
ATOM   93    N ND2 . ASN A 1 24  ? 160.213 118.119 163.220 1.00 62.52  ? 24  ASN A ND2 1 
ATOM   94    N N   . GLY A 1 25  ? 157.759 122.769 164.674 1.00 55.92  ? 25  GLY A N   1 
ATOM   95    C CA  . GLY A 1 25  ? 156.519 123.253 164.114 1.00 55.92  ? 25  GLY A CA  1 
ATOM   96    C C   . GLY A 1 25  ? 156.702 123.848 162.725 1.00 55.92  ? 25  GLY A C   1 
ATOM   97    O O   . GLY A 1 25  ? 157.802 123.939 162.189 1.00 55.92  ? 25  GLY A O   1 
ATOM   98    N N   . THR A 1 26  ? 155.576 124.267 162.150 1.00 50.94  ? 26  THR A N   1 
ATOM   99    C CA  . THR A 1 26  ? 155.536 124.792 160.791 1.00 50.94  ? 26  THR A CA  1 
ATOM   100   C C   . THR A 1 26  ? 154.946 126.196 160.780 1.00 50.94  ? 26  THR A C   1 
ATOM   101   O O   . THR A 1 26  ? 154.035 126.503 161.552 1.00 50.94  ? 26  THR A O   1 
ATOM   102   C CB  . THR A 1 26  ? 154.721 123.879 159.872 1.00 50.94  ? 26  THR A CB  1 
ATOM   103   O OG1 . THR A 1 26  ? 153.620 123.323 160.601 1.00 50.94  ? 26  THR A OG1 1 
ATOM   104   C CG2 . THR A 1 26  ? 155.586 122.752 159.345 1.00 50.94  ? 26  THR A CG2 1 
ATOM   105   N N   . ILE A 1 27  ? 155.459 127.038 159.892 1.00 48.01  ? 27  ILE A N   1 
ATOM   106   C CA  . ILE A 1 27  ? 155.049 128.435 159.789 1.00 48.01  ? 27  ILE A CA  1 
ATOM   107   C C   . ILE A 1 27  ? 153.875 128.553 158.825 1.00 48.01  ? 27  ILE A C   1 
ATOM   108   O O   . ILE A 1 27  ? 153.884 127.961 157.741 1.00 48.01  ? 27  ILE A O   1 
ATOM   109   C CB  . ILE A 1 27  ? 156.229 129.312 159.331 1.00 48.01  ? 27  ILE A CB  1 
ATOM   110   C CG1 . ILE A 1 27  ? 157.440 129.108 160.243 1.00 48.01  ? 27  ILE A CG1 1 
ATOM   111   C CG2 . ILE A 1 27  ? 155.828 130.770 159.294 1.00 48.01  ? 27  ILE A CG2 1 
ATOM   112   C CD1 . ILE A 1 27  ? 157.166 129.399 161.696 1.00 48.01  ? 27  ILE A CD1 1 
ATOM   113   N N   . VAL A 1 28  ? 152.854 129.318 159.222 1.00 44.58  ? 28  VAL A N   1 
ATOM   114   C CA  . VAL A 1 28  ? 151.715 129.629 158.366 1.00 44.58  ? 28  VAL A CA  1 
ATOM   115   C C   . VAL A 1 28  ? 151.412 131.119 158.481 1.00 44.58  ? 28  VAL A C   1 
ATOM   116   O O   . VAL A 1 28  ? 151.983 131.832 159.306 1.00 44.58  ? 28  VAL A O   1 
ATOM   117   C CB  . VAL A 1 28  ? 150.458 128.799 158.712 1.00 44.58  ? 28  VAL A CB  1 
ATOM   118   C CG1 . VAL A 1 28  ? 150.715 127.316 158.510 1.00 44.58  ? 28  VAL A CG1 1 
ATOM   119   C CG2 . VAL A 1 28  ? 150.003 129.085 160.130 1.00 44.58  ? 28  VAL A CG2 1 
ATOM   120   N N   . LYS A 1 29  ? 150.494 131.580 157.636 1.00 43.67  ? 29  LYS A N   1 
ATOM   121   C CA  . LYS A 1 29  ? 150.083 132.976 157.590 1.00 43.67  ? 29  LYS A CA  1 
ATOM   122   C C   . LYS A 1 29  ? 148.580 133.081 157.813 1.00 43.67  ? 29  LYS A C   1 
ATOM   123   O O   . LYS A 1 29  ? 147.807 132.296 157.257 1.00 43.67  ? 29  LYS A O   1 
ATOM   124   C CB  . LYS A 1 29  ? 150.458 133.611 156.246 1.00 43.67  ? 29  LYS A CB  1 
ATOM   125   C CG  . LYS A 1 29  ? 149.842 134.975 156.007 1.00 43.67  ? 29  LYS A CG  1 
ATOM   126   C CD  . LYS A 1 29  ? 149.404 135.138 154.563 1.00 43.67  ? 29  LYS A CD  1 
ATOM   127   C CE  . LYS A 1 29  ? 150.527 135.694 153.709 1.00 43.67  ? 29  LYS A CE  1 
ATOM   128   N NZ  . LYS A 1 29  ? 150.450 135.190 152.313 1.00 43.67  ? 29  LYS A NZ  1 
ATOM   129   N N   . THR A 1 30  ? 148.171 134.049 158.626 1.00 42.99  ? 30  THR A N   1 
ATOM   130   C CA  . THR A 1 30  ? 146.765 134.315 158.904 1.00 42.99  ? 30  THR A CA  1 
ATOM   131   C C   . THR A 1 30  ? 146.409 135.733 158.462 1.00 42.99  ? 30  THR A C   1 
ATOM   132   O O   . THR A 1 30  ? 147.232 136.464 157.911 1.00 42.99  ? 30  THR A O   1 
ATOM   133   C CB  . THR A 1 30  ? 146.444 134.118 160.391 1.00 42.99  ? 30  THR A CB  1 
ATOM   134   O OG1 . THR A 1 30  ? 147.075 135.148 161.162 1.00 42.99  ? 30  THR A OG1 1 
ATOM   135   C CG2 . THR A 1 30  ? 146.929 132.762 160.874 1.00 42.99  ? 30  THR A CG2 1 
ATOM   136   N N   . ILE A 1 31  ? 145.156 136.114 158.717 1.00 43.21  ? 31  ILE A N   1 
ATOM   137   C CA  . ILE A 1 31  ? 144.696 137.462 158.396 1.00 43.21  ? 31  ILE A CA  1 
ATOM   138   C C   . ILE A 1 31  ? 145.423 138.495 159.251 1.00 43.21  ? 31  ILE A C   1 
ATOM   139   O O   . ILE A 1 31  ? 145.745 139.594 158.784 1.00 43.21  ? 31  ILE A O   1 
ATOM   140   C CB  . ILE A 1 31  ? 143.168 137.551 158.572 1.00 43.21  ? 31  ILE A CB  1 
ATOM   141   C CG1 . ILE A 1 31  ? 142.454 136.936 157.368 1.00 43.21  ? 31  ILE A CG1 1 
ATOM   142   C CG2 . ILE A 1 31  ? 142.718 138.993 158.790 1.00 43.21  ? 31  ILE A CG2 1 
ATOM   143   C CD1 . ILE A 1 31  ? 142.782 137.610 156.063 1.00 43.21  ? 31  ILE A CD1 1 
ATOM   144   N N   . THR A 1 32  ? 145.713 138.152 160.502 1.00 47.97  ? 32  THR A N   1 
ATOM   145   C CA  . THR A 1 32  ? 146.253 139.087 161.481 1.00 47.97  ? 32  THR A CA  1 
ATOM   146   C C   . THR A 1 32  ? 147.773 139.050 161.587 1.00 47.97  ? 32  THR A C   1 
ATOM   147   O O   . THR A 1 32  ? 148.398 140.101 161.755 1.00 47.97  ? 32  THR A O   1 
ATOM   148   C CB  . THR A 1 32  ? 145.618 138.807 162.851 1.00 47.97  ? 32  THR A CB  1 
ATOM   149   O OG1 . THR A 1 32  ? 144.310 139.389 162.897 1.00 47.97  ? 32  THR A OG1 1 
ATOM   150   C CG2 . THR A 1 32  ? 146.455 139.369 163.982 1.00 47.97  ? 32  THR A CG2 1 
ATOM   151   N N   . ASP A 1 33  ? 148.395 137.879 161.466 1.00 50.09  ? 33  ASP A N   1 
ATOM   152   C CA  . ASP A 1 33  ? 149.835 137.739 161.637 1.00 50.09  ? 33  ASP A CA  1 
ATOM   153   C C   . ASP A 1 33  ? 150.490 137.301 160.335 1.00 50.09  ? 33  ASP A C   1 
ATOM   154   O O   . ASP A 1 33  ? 149.940 136.481 159.595 1.00 50.09  ? 33  ASP A O   1 
ATOM   155   C CB  . ASP A 1 33  ? 150.169 136.731 162.742 1.00 50.09  ? 33  ASP A CB  1 
ATOM   156   C CG  . ASP A 1 33  ? 149.277 136.879 163.956 1.00 50.09  ? 33  ASP A CG  1 
ATOM   157   O OD1 . ASP A 1 33  ? 149.579 137.732 164.818 1.00 50.09  ? 33  ASP A OD1 1 
ATOM   158   O OD2 . ASP A 1 33  ? 148.275 136.141 164.053 1.00 50.09  ? 33  ASP A OD2 1 
ATOM   159   N N   . ASP A 1 34  ? 151.677 137.852 160.065 1.00 52.58  ? 34  ASP A N   1 
ATOM   160   C CA  . ASP A 1 34  ? 152.412 137.482 158.860 1.00 52.58  ? 34  ASP A CA  1 
ATOM   161   C C   . ASP A 1 34  ? 152.938 136.054 158.944 1.00 52.58  ? 34  ASP A C   1 
ATOM   162   O O   . ASP A 1 34  ? 152.999 135.350 157.930 1.00 52.58  ? 34  ASP A O   1 
ATOM   163   C CB  . ASP A 1 34  ? 153.564 138.458 158.622 1.00 52.58  ? 34  ASP A CB  1 
ATOM   164   C CG  . ASP A 1 34  ? 153.090 139.884 158.422 1.00 52.58  ? 34  ASP A CG  1 
ATOM   165   O OD1 . ASP A 1 34  ? 152.808 140.264 157.266 1.00 52.58  ? 34  ASP A OD1 1 
ATOM   166   O OD2 . ASP A 1 34  ? 153.000 140.625 159.422 1.00 52.58  ? 34  ASP A OD2 1 
ATOM   167   N N   . GLN A 1 35  ? 153.333 135.611 160.136 1.00 51.74  ? 35  GLN A N   1 
ATOM   168   C CA  . GLN A 1 35  ? 153.864 134.262 160.302 1.00 51.74  ? 35  GLN A CA  1 
ATOM   169   C C   . GLN A 1 35  ? 153.649 133.807 161.735 1.00 51.74  ? 35  GLN A C   1 
ATOM   170   O O   . GLN A 1 35  ? 154.068 134.488 162.675 1.00 51.74  ? 35  GLN A O   1 
ATOM   171   C CB  . GLN A 1 35  ? 155.348 134.205 159.936 1.00 51.74  ? 35  GLN A CB  1 
ATOM   172   C CG  . GLN A 1 35  ? 156.127 135.466 160.236 1.00 51.74  ? 35  GLN A CG  1 
ATOM   173   C CD  . GLN A 1 35  ? 157.569 135.371 159.782 1.00 51.74  ? 35  GLN A CD  1 
ATOM   174   O OE1 . GLN A 1 35  ? 157.994 134.351 159.239 1.00 51.74  ? 35  GLN A OE1 1 
ATOM   175   N NE2 . GLN A 1 35  ? 158.332 136.435 160.004 1.00 51.74  ? 35  GLN A NE2 1 
ATOM   176   N N   . ILE A 1 36  ? 153.001 132.658 161.898 1.00 50.80  ? 36  ILE A N   1 
ATOM   177   C CA  . ILE A 1 36  ? 152.776 132.046 163.200 1.00 50.80  ? 36  ILE A CA  1 
ATOM   178   C C   . ILE A 1 36  ? 153.094 130.560 163.091 1.00 50.80  ? 36  ILE A C   1 
ATOM   179   O O   . ILE A 1 36  ? 152.813 129.929 162.066 1.00 50.80  ? 36  ILE A O   1 
ATOM   180   C CB  . ILE A 1 36  ? 151.333 132.280 163.699 1.00 50.80  ? 36  ILE A CB  1 
ATOM   181   C CG1 . ILE A 1 36  ? 151.155 131.733 165.116 1.00 50.80  ? 36  ILE A CG1 1 
ATOM   182   C CG2 . ILE A 1 36  ? 150.317 131.672 162.744 1.00 50.80  ? 36  ILE A CG2 1 
ATOM   183   C CD1 . ILE A 1 36  ? 149.725 131.747 165.598 1.00 50.80  ? 36  ILE A CD1 1 
ATOM   184   N N   . GLU A 1 37  ? 153.704 130.009 164.136 1.00 53.14  ? 37  GLU A N   1 
ATOM   185   C CA  . GLU A 1 37  ? 154.134 128.618 164.138 1.00 53.14  ? 37  GLU A CA  1 
ATOM   186   C C   . GLU A 1 37  ? 153.073 127.737 164.785 1.00 53.14  ? 37  GLU A C   1 
ATOM   187   O O   . GLU A 1 37  ? 152.607 128.023 165.891 1.00 53.14  ? 37  GLU A O   1 
ATOM   188   C CB  . GLU A 1 37  ? 155.466 128.466 164.873 1.00 53.14  ? 37  GLU A CB  1 
ATOM   189   C CG  . GLU A 1 37  ? 156.159 127.139 164.625 1.00 53.14  ? 37  GLU A CG  1 
ATOM   190   C CD  . GLU A 1 37  ? 157.299 126.885 165.589 1.00 53.14  ? 37  GLU A CD  1 
ATOM   191   O OE1 . GLU A 1 37  ? 158.167 127.770 165.734 1.00 53.14  ? 37  GLU A OE1 1 
ATOM   192   O OE2 . GLU A 1 37  ? 157.326 125.800 166.206 1.00 53.14  ? 37  GLU A OE2 1 
ATOM   193   N N   . VAL A 1 38  ? 152.703 126.662 164.094 1.00 50.88  ? 38  VAL A N   1 
ATOM   194   C CA  . VAL A 1 38  ? 151.704 125.717 164.568 1.00 50.88  ? 38  VAL A CA  1 
ATOM   195   C C   . VAL A 1 38  ? 152.332 124.328 164.618 1.00 50.88  ? 38  VAL A C   1 
ATOM   196   O O   . VAL A 1 38  ? 153.442 124.103 164.135 1.00 50.88  ? 38  VAL A O   1 
ATOM   197   C CB  . VAL A 1 38  ? 150.434 125.717 163.695 1.00 50.88  ? 38  VAL A CB  1 
ATOM   198   C CG1 . VAL A 1 38  ? 149.781 127.086 163.713 1.00 50.88  ? 38  VAL A CG1 1 
ATOM   199   C CG2 . VAL A 1 38  ? 150.760 125.294 162.277 1.00 50.88  ? 38  VAL A CG2 1 
ATOM   200   N N   . THR A 1 39  ? 151.594 123.391 165.213 1.00 52.63  ? 39  THR A N   1 
ATOM   201   C CA  . THR A 1 39  ? 152.104 122.047 165.452 1.00 52.63  ? 39  THR A CA  1 
ATOM   202   C C   . THR A 1 39  ? 151.993 121.125 164.243 1.00 52.63  ? 39  THR A C   1 
ATOM   203   O O   . THR A 1 39  ? 152.643 120.076 164.233 1.00 52.63  ? 39  THR A O   1 
ATOM   204   C CB  . THR A 1 39  ? 151.372 121.411 166.638 1.00 52.63  ? 39  THR A CB  1 
ATOM   205   O OG1 . THR A 1 39  ? 149.967 121.362 166.368 1.00 52.63  ? 39  THR A OG1 1 
ATOM   206   C CG2 . THR A 1 39  ? 151.607 122.215 167.904 1.00 52.63  ? 39  THR A CG2 1 
ATOM   207   N N   . ASN A 1 40  ? 151.206 121.483 163.230 1.00 49.32  ? 40  ASN A N   1 
ATOM   208   C CA  . ASN A 1 40  ? 150.993 120.604 162.088 1.00 49.32  ? 40  ASN A CA  1 
ATOM   209   C C   . ASN A 1 40  ? 150.320 121.395 160.974 1.00 49.32  ? 40  ASN A C   1 
ATOM   210   O O   . ASN A 1 40  ? 149.497 122.272 161.247 1.00 49.32  ? 40  ASN A O   1 
ATOM   211   C CB  . ASN A 1 40  ? 150.137 119.392 162.487 1.00 49.32  ? 40  ASN A CB  1 
ATOM   212   C CG  . ASN A 1 40  ? 150.183 118.277 161.465 1.00 49.32  ? 40  ASN A CG  1 
ATOM   213   O OD1 . ASN A 1 40  ? 151.138 118.150 160.703 1.00 49.32  ? 40  ASN A OD1 1 
ATOM   214   N ND2 . ASN A 1 40  ? 149.140 117.457 161.450 1.00 49.32  ? 40  ASN A ND2 1 
ATOM   215   N N   . ALA A 1 41  ? 150.673 121.082 159.729 1.00 42.48  ? 41  ALA A N   1 
ATOM   216   C CA  . ALA A 1 41  ? 150.125 121.778 158.571 1.00 42.48  ? 41  ALA A CA  1 
ATOM   217   C C   . ALA A 1 41  ? 150.197 120.866 157.356 1.00 42.48  ? 41  ALA A C   1 
ATOM   218   O O   . ALA A 1 41  ? 150.931 119.875 157.343 1.00 42.48  ? 41  ALA A O   1 
ATOM   219   C CB  . ALA A 1 41  ? 150.867 123.091 158.302 1.00 42.48  ? 41  ALA A CB  1 
ATOM   220   N N   . THR A 1 42  ? 149.422 121.217 156.329 1.00 38.47  ? 42  THR A N   1 
ATOM   221   C CA  . THR A 1 42  ? 149.363 120.452 155.089 1.00 38.47  ? 42  THR A CA  1 
ATOM   222   C C   . THR A 1 42  ? 149.531 121.371 153.885 1.00 38.47  ? 42  THR A C   1 
ATOM   223   O O   . THR A 1 42  ? 149.162 122.546 153.921 1.00 38.47  ? 42  THR A O   1 
ATOM   224   C CB  . THR A 1 42  ? 148.038 119.681 154.946 1.00 38.47  ? 42  THR A CB  1 
ATOM   225   O OG1 . THR A 1 42  ? 146.967 120.601 154.713 1.00 38.47  ? 42  THR A OG1 1 
ATOM   226   C CG2 . THR A 1 42  ? 147.741 118.868 156.194 1.00 38.47  ? 42  THR A CG2 1 
ATOM   227   N N   . GLU A 1 43  ? 150.083 120.815 152.808 1.00 34.66  ? 43  GLU A N   1 
ATOM   228   C CA  . GLU A 1 43  ? 150.291 121.550 151.567 1.00 34.66  ? 43  GLU A CA  1 
ATOM   229   C C   . GLU A 1 43  ? 149.064 121.419 150.672 1.00 34.66  ? 43  GLU A C   1 
ATOM   230   O O   . GLU A 1 43  ? 148.522 120.322 150.510 1.00 34.66  ? 43  GLU A O   1 
ATOM   231   C CB  . GLU A 1 43  ? 151.537 121.038 150.843 1.00 34.66  ? 43  GLU A CB  1 
ATOM   232   C CG  . GLU A 1 43  ? 151.722 121.600 149.445 1.00 34.66  ? 43  GLU A CG  1 
ATOM   233   C CD  . GLU A 1 43  ? 151.985 123.093 149.443 1.00 34.66  ? 43  GLU A CD  1 
ATOM   234   O OE1 . GLU A 1 43  ? 152.928 123.536 150.128 1.00 34.66  ? 43  GLU A OE1 1 
ATOM   235   O OE2 . GLU A 1 43  ? 151.246 123.825 148.754 1.00 34.66  ? 43  GLU A OE2 1 
ATOM   236   N N   . LEU A 1 44  ? 148.631 122.538 150.091 1.00 32.13  ? 44  LEU A N   1 
ATOM   237   C CA  . LEU A 1 44  ? 147.413 122.568 149.292 1.00 32.13  ? 44  LEU A CA  1 
ATOM   238   C C   . LEU A 1 44  ? 147.657 122.657 147.788 1.00 32.13  ? 44  LEU A C   1 
ATOM   239   O O   . LEU A 1 44  ? 146.709 122.469 147.020 1.00 32.13  ? 44  LEU A O   1 
ATOM   240   C CB  . LEU A 1 44  ? 146.527 123.743 149.724 1.00 32.13  ? 44  LEU A CB  1 
ATOM   241   C CG  . LEU A 1 44  ? 145.874 123.653 151.105 1.00 32.13  ? 44  LEU A CG  1 
ATOM   242   C CD1 . LEU A 1 44  ? 144.888 124.787 151.300 1.00 32.13  ? 44  LEU A CD1 1 
ATOM   243   C CD2 . LEU A 1 44  ? 145.191 122.310 151.300 1.00 32.13  ? 44  LEU A CD2 1 
ATOM   244   N N   . VAL A 1 45  ? 148.883 122.930 147.345 1.00 30.15  ? 45  VAL A N   1 
ATOM   245   C CA  . VAL A 1 45  ? 149.200 123.089 145.928 1.00 30.15  ? 45  VAL A CA  1 
ATOM   246   C C   . VAL A 1 45  ? 150.044 121.907 145.471 1.00 30.15  ? 45  VAL A C   1 
ATOM   247   O O   . VAL A 1 45  ? 151.074 121.598 146.081 1.00 30.15  ? 45  VAL A O   1 
ATOM   248   C CB  . VAL A 1 45  ? 149.932 124.417 145.656 1.00 30.15  ? 45  VAL A CB  1 
ATOM   249   C CG1 . VAL A 1 45  ? 150.196 124.584 144.166 1.00 30.15  ? 45  VAL A CG1 1 
ATOM   250   C CG2 . VAL A 1 45  ? 149.136 125.594 146.199 1.00 30.15  ? 45  VAL A CG2 1 
ATOM   251   N N   . GLN A 1 46  ? 149.608 121.250 144.397 1.00 30.36  ? 46  GLN A N   1 
ATOM   252   C CA  . GLN A 1 46  ? 150.378 120.189 143.757 1.00 30.36  ? 46  GLN A CA  1 
ATOM   253   C C   . GLN A 1 46  ? 151.317 120.819 142.733 1.00 30.36  ? 46  GLN A C   1 
ATOM   254   O O   . GLN A 1 46  ? 150.867 121.550 141.846 1.00 30.36  ? 46  GLN A O   1 
ATOM   255   C CB  . GLN A 1 46  ? 149.443 119.175 143.097 1.00 30.36  ? 46  GLN A CB  1 
ATOM   256   C CG  . GLN A 1 46  ? 150.124 118.157 142.197 1.00 30.36  ? 46  GLN A CG  1 
ATOM   257   C CD  . GLN A 1 46  ? 150.806 117.047 142.971 1.00 30.36  ? 46  GLN A CD  1 
ATOM   258   O OE1 . GLN A 1 46  ? 150.236 116.480 143.899 1.00 30.36  ? 46  GLN A OE1 1 
ATOM   259   N NE2 . GLN A 1 46  ? 152.032 116.728 142.587 1.00 30.36  ? 46  GLN A NE2 1 
ATOM   260   N N   . ASN A 1 47  ? 152.618 120.541 142.853 1.00 31.90  ? 47  ASN A N   1 
ATOM   261   C CA  . ASN A 1 47  ? 153.613 121.251 142.055 1.00 31.90  ? 47  ASN A CA  1 
ATOM   262   C C   . ASN A 1 47  ? 154.552 120.322 141.289 1.00 31.90  ? 47  ASN A C   1 
ATOM   263   O O   . ASN A 1 47  ? 155.621 120.762 140.858 1.00 31.90  ? 47  ASN A O   1 
ATOM   264   C CB  . ASN A 1 47  ? 154.424 122.209 142.937 1.00 31.90  ? 47  ASN A CB  1 
ATOM   265   C CG  . ASN A 1 47  ? 155.392 121.490 143.871 1.00 31.90  ? 47  ASN A CG  1 
ATOM   266   O OD1 . ASN A 1 47  ? 155.346 120.271 144.030 1.00 31.90  ? 47  ASN A OD1 1 
ATOM   267   N ND2 . ASN A 1 47  ? 156.276 122.254 144.495 1.00 31.90  ? 47  ASN A ND2 1 
ATOM   268   N N   . SER A 1 48  ? 154.190 119.056 141.100 1.00 33.39  ? 48  SER A N   1 
ATOM   269   C CA  . SER A 1 48  ? 155.082 118.139 140.405 1.00 33.39  ? 48  SER A CA  1 
ATOM   270   C C   . SER A 1 48  ? 154.276 117.073 139.677 1.00 33.39  ? 48  SER A C   1 
ATOM   271   O O   . SER A 1 48  ? 153.111 116.821 139.989 1.00 33.39  ? 48  SER A O   1 
ATOM   272   C CB  . SER A 1 48  ? 156.080 117.486 141.370 1.00 33.39  ? 48  SER A CB  1 
ATOM   273   O OG  . SER A 1 48  ? 155.412 116.752 142.380 1.00 33.39  ? 48  SER A OG  1 
ATOM   274   N N   . SER A 1 49  ? 154.925 116.450 138.694 1.00 35.12  ? 49  SER A N   1 
ATOM   275   C CA  . SER A 1 49  ? 154.348 115.363 137.918 1.00 35.12  ? 49  SER A CA  1 
ATOM   276   C C   . SER A 1 49  ? 155.404 114.289 137.700 1.00 35.12  ? 49  SER A C   1 
ATOM   277   O O   . SER A 1 49  ? 156.603 114.572 137.700 1.00 35.12  ? 49  SER A O   1 
ATOM   278   C CB  . SER A 1 49  ? 153.821 115.852 136.564 1.00 35.12  ? 49  SER A CB  1 
ATOM   279   O OG  . SER A 1 49  ? 153.390 114.768 135.763 1.00 35.12  ? 49  SER A OG  1 
ATOM   280   N N   . THR A 1 50  ? 154.947 113.049 137.513 1.00 37.56  ? 50  THR A N   1 
ATOM   281   C CA  . THR A 1 50  ? 155.867 111.962 137.201 1.00 37.56  ? 50  THR A CA  1 
ATOM   282   C C   . THR A 1 50  ? 156.406 112.036 135.779 1.00 37.56  ? 50  THR A C   1 
ATOM   283   O O   . THR A 1 50  ? 157.369 111.330 135.466 1.00 37.56  ? 50  THR A O   1 
ATOM   284   C CB  . THR A 1 50  ? 155.191 110.605 137.408 1.00 37.56  ? 50  THR A CB  1 
ATOM   285   O OG1 . THR A 1 50  ? 154.202 110.399 136.392 1.00 37.56  ? 50  THR A OG1 1 
ATOM   286   C CG2 . THR A 1 50  ? 154.532 110.537 138.775 1.00 37.56  ? 50  THR A CG2 1 
ATOM   287   N N   . GLY A 1 51  ? 155.819 112.866 134.920 1.00 35.88  ? 51  GLY A N   1 
ATOM   288   C CA  . GLY A 1 51  ? 156.261 112.974 133.547 1.00 35.88  ? 51  GLY A CA  1 
ATOM   289   C C   . GLY A 1 51  ? 155.679 111.953 132.597 1.00 35.88  ? 51  GLY A C   1 
ATOM   290   O O   . GLY A 1 51  ? 156.103 111.901 131.439 1.00 35.88  ? 51  GLY A O   1 
ATOM   291   N N   . LYS A 1 52  ? 154.723 111.143 133.043 1.00 36.12  ? 52  LYS A N   1 
ATOM   292   C CA  . LYS A 1 52  ? 154.105 110.118 132.218 1.00 36.12  ? 52  LYS A CA  1 
ATOM   293   C C   . LYS A 1 52  ? 152.602 110.342 132.154 1.00 36.12  ? 52  LYS A C   1 
ATOM   294   O O   . LYS A 1 52  ? 152.000 110.892 133.079 1.00 36.12  ? 52  LYS A O   1 
ATOM   295   C CB  . LYS A 1 52  ? 154.379 108.711 132.764 1.00 36.12  ? 52  LYS A CB  1 
ATOM   296   C CG  . LYS A 1 52  ? 155.822 108.429 133.142 1.00 36.12  ? 52  LYS A CG  1 
ATOM   297   C CD  . LYS A 1 52  ? 156.773 108.741 132.008 1.00 36.12  ? 52  LYS A CD  1 
ATOM   298   C CE  . LYS A 1 52  ? 157.991 107.836 132.049 1.00 36.12  ? 52  LYS A CE  1 
ATOM   299   N NZ  . LYS A 1 52  ? 158.092 107.100 133.339 1.00 36.12  ? 52  LYS A NZ  1 
ATOM   300   N N   . ILE A 1 53  ? 151.997 109.899 131.057 1.00 34.80  ? 53  ILE A N   1 
ATOM   301   C CA  . ILE A 1 53  ? 150.551 109.949 130.880 1.00 34.80  ? 53  ILE A CA  1 
ATOM   302   C C   . ILE A 1 53  ? 150.004 108.543 131.086 1.00 34.80  ? 53  ILE A C   1 
ATOM   303   O O   . ILE A 1 53  ? 150.446 107.594 130.429 1.00 34.80  ? 53  ILE A O   1 
ATOM   304   C CB  . ILE A 1 53  ? 150.171 110.499 129.496 1.00 34.80  ? 53  ILE A CB  1 
ATOM   305   C CG1 . ILE A 1 53  ? 150.622 111.954 129.361 1.00 34.80  ? 53  ILE A CG1 1 
ATOM   306   C CG2 . ILE A 1 53  ? 148.672 110.384 129.265 1.00 34.80  ? 53  ILE A CG2 1 
ATOM   307   C CD1 . ILE A 1 53  ? 150.450 112.523 127.977 1.00 34.80  ? 53  ILE A CD1 1 
ATOM   308   N N   . CYS A 1 54  ? 149.052 108.405 132.004 1.00 37.87  ? 54  CYS A N   1 
ATOM   309   C CA  . CYS A 1 54  ? 148.470 107.106 132.312 1.00 37.87  ? 54  CYS A CA  1 
ATOM   310   C C   . CYS A 1 54  ? 147.376 106.758 131.311 1.00 37.87  ? 54  CYS A C   1 
ATOM   311   O O   . CYS A 1 54  ? 146.602 107.621 130.890 1.00 37.87  ? 54  CYS A O   1 
ATOM   312   C CB  . CYS A 1 54  ? 147.902 107.100 133.732 1.00 37.87  ? 54  CYS A CB  1 
ATOM   313   S SG  . CYS A 1 54  ? 149.150 107.134 135.044 1.00 37.87  ? 54  CYS A SG  1 
ATOM   314   N N   . ASN A 1 55  ? 147.305 105.480 130.941 1.00 39.38  ? 55  ASN A N   1 
ATOM   315   C CA  . ASN A 1 55  ? 146.366 105.019 129.926 1.00 39.38  ? 55  ASN A CA  1 
ATOM   316   C C   . ASN A 1 55  ? 145.007 104.619 130.491 1.00 39.38  ? 55  ASN A C   1 
ATOM   317   O O   . ASN A 1 55  ? 144.152 104.159 129.730 1.00 39.38  ? 55  ASN A O   1 
ATOM   318   C CB  . ASN A 1 55  ? 146.969 103.851 129.134 1.00 39.38  ? 55  ASN A CB  1 
ATOM   319   C CG  . ASN A 1 55  ? 147.236 102.624 129.991 1.00 39.38  ? 55  ASN A CG  1 
ATOM   320   O OD1 . ASN A 1 55  ? 147.005 102.624 131.198 1.00 39.38  ? 55  ASN A OD1 1 
ATOM   321   N ND2 . ASN A 1 55  ? 147.730 101.567 129.360 1.00 39.38  ? 55  ASN A ND2 1 
ATOM   322   N N   . ASN A 1 56  ? 144.785 104.778 131.790 1.00 38.60  ? 56  ASN A N   1 
ATOM   323   C CA  . ASN A 1 56  ? 143.490 104.517 132.395 1.00 38.60  ? 56  ASN A CA  1 
ATOM   324   C C   . ASN A 1 56  ? 143.125 105.648 133.343 1.00 38.60  ? 56  ASN A C   1 
ATOM   325   O O   . ASN A 1 56  ? 144.007 106.250 133.961 1.00 38.60  ? 56  ASN A O   1 
ATOM   326   C CB  . ASN A 1 56  ? 143.492 103.182 133.154 1.00 38.60  ? 56  ASN A CB  1 
ATOM   327   C CG  . ASN A 1 56  ? 143.059 102.022 132.285 1.00 38.60  ? 56  ASN A CG  1 
ATOM   328   O OD1 . ASN A 1 56  ? 141.938 101.997 131.781 1.00 38.60  ? 56  ASN A OD1 1 
ATOM   329   N ND2 . ASN A 1 56  ? 143.946 101.054 132.104 1.00 38.60  ? 56  ASN A ND2 1 
ATOM   330   N N   . PRO A 1 57  ? 141.824 105.956 133.490 1.00 35.77  ? 57  PRO A N   1 
ATOM   331   C CA  . PRO A 1 57  ? 140.678 105.303 132.850 1.00 35.77  ? 57  PRO A CA  1 
ATOM   332   C C   . PRO A 1 57  ? 140.285 105.877 131.486 1.00 35.77  ? 57  PRO A C   1 
ATOM   333   O O   . PRO A 1 57  ? 139.471 105.269 130.799 1.00 35.77  ? 57  PRO A O   1 
ATOM   334   C CB  . PRO A 1 57  ? 139.561 105.537 133.861 1.00 35.77  ? 57  PRO A CB  1 
ATOM   335   C CG  . PRO A 1 57  ? 139.875 106.878 134.414 1.00 35.77  ? 57  PRO A CG  1 
ATOM   336   C CD  . PRO A 1 57  ? 141.384 106.998 134.435 1.00 35.77  ? 57  PRO A CD  1 
ATOM   337   N N   . HIS A 1 58  ? 140.843 107.023 131.107 1.00 33.08  ? 58  HIS A N   1 
ATOM   338   C CA  . HIS A 1 58  ? 140.533 107.610 129.811 1.00 33.08  ? 58  HIS A CA  1 
ATOM   339   C C   . HIS A 1 58  ? 141.211 106.826 128.692 1.00 33.08  ? 58  HIS A C   1 
ATOM   340   O O   . HIS A 1 58  ? 142.286 106.250 128.871 1.00 33.08  ? 58  HIS A O   1 
ATOM   341   C CB  . HIS A 1 58  ? 140.978 109.072 129.760 1.00 33.08  ? 58  HIS A CB  1 
ATOM   342   C CG  . HIS A 1 58  ? 140.497 109.898 130.912 1.00 33.08  ? 58  HIS A CG  1 
ATOM   343   N ND1 . HIS A 1 58  ? 139.167 110.200 131.107 1.00 33.08  ? 58  HIS A ND1 1 
ATOM   344   C CD2 . HIS A 1 58  ? 141.170 110.499 131.921 1.00 33.08  ? 58  HIS A CD2 1 
ATOM   345   C CE1 . HIS A 1 58  ? 139.041 110.944 132.191 1.00 33.08  ? 58  HIS A CE1 1 
ATOM   346   N NE2 . HIS A 1 58  ? 140.242 111.139 132.704 1.00 33.08  ? 58  HIS A NE2 1 
ATOM   347   N N   . LYS A 1 59  ? 140.570 106.806 127.526 1.00 29.83  ? 59  LYS A N   1 
ATOM   348   C CA  . LYS A 1 59  ? 141.145 106.181 126.339 1.00 29.83  ? 59  LYS A CA  1 
ATOM   349   C C   . LYS A 1 59  ? 142.046 107.197 125.645 1.00 29.83  ? 59  LYS A C   1 
ATOM   350   O O   . LYS A 1 59  ? 141.561 108.151 125.030 1.00 29.83  ? 59  LYS A O   1 
ATOM   351   C CB  . LYS A 1 59  ? 140.053 105.679 125.399 1.00 29.83  ? 59  LYS A CB  1 
ATOM   352   C CG  . LYS A 1 59  ? 140.576 104.804 124.268 1.00 29.83  ? 59  LYS A CG  1 
ATOM   353   C CD  . LYS A 1 59  ? 139.467 104.400 123.313 1.00 29.83  ? 59  LYS A CD  1 
ATOM   354   C CE  . LYS A 1 59  ? 139.907 103.268 122.399 1.00 29.83  ? 59  LYS A CE  1 
ATOM   355   N NZ  . LYS A 1 59  ? 141.071 103.648 121.550 1.00 29.83  ? 59  LYS A NZ  1 
ATOM   356   N N   . VAL A 1 60  ? 143.354 106.990 125.740 1.00 29.17  ? 60  VAL A N   1 
ATOM   357   C CA  . VAL A 1 60  ? 144.344 107.902 125.181 1.00 29.17  ? 60  VAL A CA  1 
ATOM   358   C C   . VAL A 1 60  ? 144.849 107.314 123.871 1.00 29.17  ? 60  VAL A C   1 
ATOM   359   O O   . VAL A 1 60  ? 145.328 106.175 123.836 1.00 29.17  ? 60  VAL A O   1 
ATOM   360   C CB  . VAL A 1 60  ? 145.501 108.140 126.165 1.00 29.17  ? 60  VAL A CB  1 
ATOM   361   C CG1 . VAL A 1 60  ? 146.540 109.058 125.551 1.00 29.17  ? 60  VAL A CG1 1 
ATOM   362   C CG2 . VAL A 1 60  ? 144.979 108.722 127.467 1.00 29.17  ? 60  VAL A CG2 1 
ATOM   363   N N   . LEU A 1 61  ? 144.746 108.088 122.794 1.00 28.91  ? 61  LEU A N   1 
ATOM   364   C CA  . LEU A 1 61  ? 145.226 107.681 121.479 1.00 28.91  ? 61  LEU A CA  1 
ATOM   365   C C   . LEU A 1 61  ? 146.414 108.551 121.093 1.00 28.91  ? 61  LEU A C   1 
ATOM   366   O O   . LEU A 1 61  ? 146.301 109.780 121.050 1.00 28.91  ? 61  LEU A O   1 
ATOM   367   C CB  . LEU A 1 61  ? 144.119 107.786 120.430 1.00 28.91  ? 61  LEU A CB  1 
ATOM   368   C CG  . LEU A 1 61  ? 144.500 107.369 119.007 1.00 28.91  ? 61  LEU A CG  1 
ATOM   369   C CD1 . LEU A 1 61  ? 144.943 105.916 118.970 1.00 28.91  ? 61  LEU A CD1 1 
ATOM   370   C CD2 . LEU A 1 61  ? 143.348 107.605 118.051 1.00 28.91  ? 61  LEU A CD2 1 
ATOM   371   N N   . ASP A 1 62  ? 147.541 107.912 120.803 1.00 31.63  ? 62  ASP A N   1 
ATOM   372   C CA  . ASP A 1 62  ? 148.778 108.609 120.471 1.00 31.63  ? 62  ASP A CA  1 
ATOM   373   C C   . ASP A 1 62  ? 148.877 108.752 118.956 1.00 31.63  ? 62  ASP A C   1 
ATOM   374   O O   . ASP A 1 62  ? 148.996 107.754 118.239 1.00 31.63  ? 62  ASP A O   1 
ATOM   375   C CB  . ASP A 1 62  ? 149.978 107.849 121.032 1.00 31.63  ? 62  ASP A CB  1 
ATOM   376   C CG  . ASP A 1 62  ? 151.300 108.530 120.736 1.00 31.63  ? 62  ASP A CG  1 
ATOM   377   O OD1 . ASP A 1 62  ? 151.312 109.752 120.493 1.00 31.63  ? 62  ASP A OD1 1 
ATOM   378   O OD2 . ASP A 1 62  ? 152.335 107.838 120.752 1.00 31.63  ? 62  ASP A OD2 1 
ATOM   379   N N   . GLY A 1 63  ? 148.820 109.989 118.467 1.00 33.04  ? 63  GLY A N   1 
ATOM   380   C CA  . GLY A 1 63  ? 149.129 110.241 117.074 1.00 33.04  ? 63  GLY A CA  1 
ATOM   381   C C   . GLY A 1 63  ? 150.611 110.501 116.920 1.00 33.04  ? 63  GLY A C   1 
ATOM   382   O O   . GLY A 1 63  ? 151.074 111.633 117.085 1.00 33.04  ? 63  GLY A O   1 
ATOM   383   N N   . ARG A 1 64  ? 151.361 109.452 116.591 1.00 35.53  ? 64  ARG A N   1 
ATOM   384   C CA  . ARG A 1 64  ? 152.816 109.480 116.670 1.00 35.53  ? 64  ARG A CA  1 
ATOM   385   C C   . ARG A 1 64  ? 153.444 110.476 115.704 1.00 35.53  ? 64  ARG A C   1 
ATOM   386   O O   . ARG A 1 64  ? 154.010 111.486 116.130 1.00 35.53  ? 64  ARG A O   1 
ATOM   387   C CB  . ARG A 1 64  ? 153.361 108.075 116.419 1.00 35.53  ? 64  ARG A CB  1 
ATOM   388   C CG  . ARG A 1 64  ? 152.955 107.087 117.495 1.00 35.53  ? 64  ARG A CG  1 
ATOM   389   C CD  . ARG A 1 64  ? 152.642 105.714 116.932 1.00 35.53  ? 64  ARG A CD  1 
ATOM   390   N NE  . ARG A 1 64  ? 152.161 104.811 117.972 1.00 35.53  ? 64  ARG A NE  1 
ATOM   391   C CZ  . ARG A 1 64  ? 152.926 104.260 118.905 1.00 35.53  ? 64  ARG A CZ  1 
ATOM   392   N NH1 . ARG A 1 64  ? 154.233 104.467 118.940 1.00 35.53  ? 64  ARG A NH1 1 
ATOM   393   N NH2 . ARG A 1 64  ? 152.367 103.480 119.824 1.00 35.53  ? 64  ARG A NH2 1 
ATOM   394   N N   . ASP A 1 65  ? 153.327 110.217 114.405 1.00 34.80  ? 65  ASP A N   1 
ATOM   395   C CA  . ASP A 1 65  ? 153.865 111.101 113.382 1.00 34.80  ? 65  ASP A CA  1 
ATOM   396   C C   . ASP A 1 65  ? 152.772 111.788 112.579 1.00 34.80  ? 65  ASP A C   1 
ATOM   397   O O   . ASP A 1 65  ? 153.062 112.382 111.537 1.00 34.80  ? 65  ASP A O   1 
ATOM   398   C CB  . ASP A 1 65  ? 154.794 110.325 112.446 1.00 34.80  ? 65  ASP A CB  1 
ATOM   399   C CG  . ASP A 1 65  ? 156.194 110.191 113.000 1.00 34.80  ? 65  ASP A CG  1 
ATOM   400   O OD1 . ASP A 1 65  ? 156.912 111.211 113.052 1.00 34.80  ? 65  ASP A OD1 1 
ATOM   401   O OD2 . ASP A 1 65  ? 156.579 109.068 113.385 1.00 34.80  ? 65  ASP A OD2 1 
ATOM   402   N N   . CYS A 1 66  ? 151.528 111.725 113.040 1.00 32.60  ? 66  CYS A N   1 
ATOM   403   C CA  . CYS A 1 66  ? 150.382 112.217 112.293 1.00 32.60  ? 66  CYS A CA  1 
ATOM   404   C C   . CYS A 1 66  ? 149.607 113.235 113.115 1.00 32.60  ? 66  CYS A C   1 
ATOM   405   O O   . CYS A 1 66  ? 149.405 113.050 114.318 1.00 32.60  ? 66  CYS A O   1 
ATOM   406   C CB  . CYS A 1 66  ? 149.454 111.063 111.900 1.00 32.60  ? 66  CYS A CB  1 
ATOM   407   S SG  . CYS A 1 66  ? 150.129 109.943 110.660 1.00 32.60  ? 66  CYS A SG  1 
ATOM   408   N N   . THR A 1 67  ? 149.183 114.312 112.462 1.00 28.45  ? 67  THR A N   1 
ATOM   409   C CA  . THR A 1 67  ? 148.205 115.211 113.050 1.00 28.45  ? 67  THR A CA  1 
ATOM   410   C C   . THR A 1 67  ? 146.802 114.641 112.858 1.00 28.45  ? 67  THR A C   1 
ATOM   411   O O   . THR A 1 67  ? 146.587 113.695 112.098 1.00 28.45  ? 67  THR A O   1 
ATOM   412   C CB  . THR A 1 67  ? 148.304 116.606 112.432 1.00 28.45  ? 67  THR A CB  1 
ATOM   413   O OG1 . THR A 1 67  ? 147.913 116.553 111.055 1.00 28.45  ? 67  THR A OG1 1 
ATOM   414   C CG2 . THR A 1 67  ? 149.724 117.140 112.532 1.00 28.45  ? 67  THR A CG2 1 
ATOM   415   N N   . LEU A 1 68  ? 145.834 115.222 113.569 1.00 26.34  ? 68  LEU A N   1 
ATOM   416   C CA  . LEU A 1 68  ? 144.458 114.747 113.453 1.00 26.34  ? 68  LEU A CA  1 
ATOM   417   C C   . LEU A 1 68  ? 143.905 114.978 112.048 1.00 26.34  ? 68  LEU A C   1 
ATOM   418   O O   . LEU A 1 68  ? 143.215 114.112 111.496 1.00 26.34  ? 68  LEU A O   1 
ATOM   419   C CB  . LEU A 1 68  ? 143.574 115.421 114.504 1.00 26.34  ? 68  LEU A CB  1 
ATOM   420   C CG  . LEU A 1 68  ? 142.114 114.961 114.543 1.00 26.34  ? 68  LEU A CG  1 
ATOM   421   C CD1 . LEU A 1 68  ? 142.016 113.457 114.758 1.00 26.34  ? 68  LEU A CD1 1 
ATOM   422   C CD2 . LEU A 1 68  ? 141.329 115.708 115.608 1.00 26.34  ? 68  LEU A CD2 1 
ATOM   423   N N   . ILE A 1 69  ? 144.207 116.133 111.450 1.00 25.99  ? 69  ILE A N   1 
ATOM   424   C CA  . ILE A 1 69  ? 143.692 116.448 110.119 1.00 25.99  ? 69  ILE A CA  1 
ATOM   425   C C   . ILE A 1 69  ? 144.261 115.491 109.075 1.00 25.99  ? 69  ILE A C   1 
ATOM   426   O O   . ILE A 1 69  ? 143.540 115.018 108.189 1.00 25.99  ? 69  ILE A O   1 
ATOM   427   C CB  . ILE A 1 69  ? 143.986 117.918 109.765 1.00 25.99  ? 69  ILE A CB  1 
ATOM   428   C CG1 . ILE A 1 69  ? 143.258 118.859 110.728 1.00 25.99  ? 69  ILE A CG1 1 
ATOM   429   C CG2 . ILE A 1 69  ? 143.598 118.216 108.324 1.00 25.99  ? 69  ILE A CG2 1 
ATOM   430   C CD1 . ILE A 1 69  ? 141.766 118.915 110.526 1.00 25.99  ? 69  ILE A CD1 1 
ATOM   431   N N   . ASP A 1 70  ? 145.561 115.196 109.155 1.00 28.01  ? 70  ASP A N   1 
ATOM   432   C CA  . ASP A 1 70  ? 146.171 114.272 108.203 1.00 28.01  ? 70  ASP A CA  1 
ATOM   433   C C   . ASP A 1 70  ? 145.577 112.874 108.325 1.00 28.01  ? 70  ASP A C   1 
ATOM   434   O O   . ASP A 1 70  ? 145.350 112.200 107.315 1.00 28.01  ? 70  ASP A O   1 
ATOM   435   C CB  . ASP A 1 70  ? 147.685 114.232 108.404 1.00 28.01  ? 70  ASP A CB  1 
ATOM   436   C CG  . ASP A 1 70  ? 148.400 115.321 107.638 1.00 28.01  ? 70  ASP A CG  1 
ATOM   437   O OD1 . ASP A 1 70  ? 147.960 115.645 106.517 1.00 28.01  ? 70  ASP A OD1 1 
ATOM   438   O OD2 . ASP A 1 70  ? 149.402 115.856 108.153 1.00 28.01  ? 70  ASP A OD2 1 
ATOM   439   N N   . ALA A 1 71  ? 145.328 112.417 109.554 1.00 27.13  ? 71  ALA A N   1 
ATOM   440   C CA  . ALA A 1 71  ? 144.686 111.122 109.749 1.00 27.13  ? 71  ALA A CA  1 
ATOM   441   C C   . ALA A 1 71  ? 143.260 111.122 109.210 1.00 27.13  ? 71  ALA A C   1 
ATOM   442   O O   . ALA A 1 71  ? 142.800 110.115 108.662 1.00 27.13  ? 71  ALA A O   1 
ATOM   443   C CB  . ALA A 1 71  ? 144.701 110.743 111.229 1.00 27.13  ? 71  ALA A CB  1 
ATOM   444   N N   . MET A 1 72  ? 142.541 112.233 109.371 1.00 27.16  ? 72  MET A N   1 
ATOM   445   C CA  . MET A 1 72  ? 141.182 112.319 108.843 1.00 27.16  ? 72  MET A CA  1 
ATOM   446   C C   . MET A 1 72  ? 141.170 112.264 107.317 1.00 27.16  ? 72  MET A C   1 
ATOM   447   O O   . MET A 1 72  ? 140.360 111.546 106.721 1.00 27.16  ? 72  MET A O   1 
ATOM   448   C CB  . MET A 1 72  ? 140.509 113.597 109.343 1.00 27.16  ? 72  MET A CB  1 
ATOM   449   C CG  . MET A 1 72  ? 139.146 113.862 108.729 1.00 27.16  ? 72  MET A CG  1 
ATOM   450   S SD  . MET A 1 72  ? 138.559 115.539 109.017 1.00 27.16  ? 72  MET A SD  1 
ATOM   451   C CE  . MET A 1 72  ? 139.623 116.456 107.908 1.00 27.16  ? 72  MET A CE  1 
ATOM   452   N N   . LEU A 1 73  ? 142.067 113.014 106.667 1.00 25.54  ? 73  LEU A N   1 
ATOM   453   C CA  . LEU A 1 73  ? 142.063 113.074 105.206 1.00 25.54  ? 73  LEU A CA  1 
ATOM   454   C C   . LEU A 1 73  ? 142.500 111.758 104.573 1.00 25.54  ? 73  LEU A C   1 
ATOM   455   O O   . LEU A 1 73  ? 141.989 111.386 103.513 1.00 25.54  ? 73  LEU A O   1 
ATOM   456   C CB  . LEU A 1 73  ? 142.961 114.209 104.713 1.00 25.54  ? 73  LEU A CB  1 
ATOM   457   C CG  . LEU A 1 73  ? 142.607 115.650 105.087 1.00 25.54  ? 73  LEU A CG  1 
ATOM   458   C CD1 . LEU A 1 73  ? 143.691 116.599 104.607 1.00 25.54  ? 73  LEU A CD1 1 
ATOM   459   C CD2 . LEU A 1 73  ? 141.254 116.055 104.524 1.00 25.54  ? 73  LEU A CD2 1 
ATOM   460   N N   . GLY A 1 74  ? 143.439 111.048 105.190 1.00 27.51  ? 74  GLY A N   1 
ATOM   461   C CA  . GLY A 1 74  ? 143.917 109.803 104.623 1.00 27.51  ? 74  GLY A CA  1 
ATOM   462   C C   . GLY A 1 74  ? 145.315 109.877 104.045 1.00 27.51  ? 74  GLY A C   1 
ATOM   463   O O   . GLY A 1 74  ? 145.584 109.306 102.986 1.00 27.51  ? 74  GLY A O   1 
ATOM   464   N N   . ASP A 1 75  ? 146.203 110.596 104.724 1.00 30.83  ? 75  ASP A N   1 
ATOM   465   C CA  . ASP A 1 75  ? 147.617 110.582 104.375 1.00 30.83  ? 75  ASP A CA  1 
ATOM   466   C C   . ASP A 1 75  ? 148.137 109.149 104.458 1.00 30.83  ? 75  ASP A C   1 
ATOM   467   O O   . ASP A 1 75  ? 147.879 108.463 105.455 1.00 30.83  ? 75  ASP A O   1 
ATOM   468   C CB  . ASP A 1 75  ? 148.397 111.494 105.325 1.00 30.83  ? 75  ASP A CB  1 
ATOM   469   C CG  . ASP A 1 75  ? 149.728 111.954 104.754 1.00 30.83  ? 75  ASP A CG  1 
ATOM   470   O OD1 . ASP A 1 75  ? 150.567 111.101 104.409 1.00 30.83  ? 75  ASP A OD1 1 
ATOM   471   O OD2 . ASP A 1 75  ? 149.945 113.178 104.671 1.00 30.83  ? 75  ASP A OD2 1 
ATOM   472   N N   . PRO A 1 76  ? 148.848 108.656 103.438 1.00 32.41  ? 76  PRO A N   1 
ATOM   473   C CA  . PRO A 1 76  ? 149.236 107.231 103.433 1.00 32.41  ? 76  PRO A CA  1 
ATOM   474   C C   . PRO A 1 76  ? 149.971 106.769 104.682 1.00 32.41  ? 76  PRO A C   1 
ATOM   475   O O   . PRO A 1 76  ? 149.621 105.725 105.249 1.00 32.41  ? 76  PRO A O   1 
ATOM   476   C CB  . PRO A 1 76  ? 150.113 107.127 102.179 1.00 32.41  ? 76  PRO A CB  1 
ATOM   477   C CG  . PRO A 1 76  ? 149.600 108.184 101.282 1.00 32.41  ? 76  PRO A CG  1 
ATOM   478   C CD  . PRO A 1 76  ? 149.177 109.323 102.168 1.00 32.41  ? 76  PRO A CD  1 
ATOM   479   N N   . HIS A 1 77  ? 150.950 107.537 105.160 1.00 32.02  ? 77  HIS A N   1 
ATOM   480   C CA  . HIS A 1 77  ? 151.666 107.142 106.368 1.00 32.02  ? 77  HIS A CA  1 
ATOM   481   C C   . HIS A 1 77  ? 150.814 107.272 107.628 1.00 32.02  ? 77  HIS A C   1 
ATOM   482   O O   . HIS A 1 77  ? 151.300 106.954 108.717 1.00 32.02  ? 77  HIS A O   1 
ATOM   483   C CB  . HIS A 1 77  ? 152.965 107.948 106.494 1.00 32.02  ? 77  HIS A CB  1 
ATOM   484   C CG  . HIS A 1 77  ? 152.825 109.238 107.241 1.00 32.02  ? 77  HIS A CG  1 
ATOM   485   N ND1 . HIS A 1 77  ? 152.265 110.366 106.682 1.00 32.02  ? 77  HIS A ND1 1 
ATOM   486   C CD2 . HIS A 1 77  ? 153.197 109.587 108.495 1.00 32.02  ? 77  HIS A CD2 1 
ATOM   487   C CE1 . HIS A 1 77  ? 152.286 111.349 107.563 1.00 32.02  ? 77  HIS A CE1 1 
ATOM   488   N NE2 . HIS A 1 77  ? 152.848 110.903 108.671 1.00 32.02  ? 77  HIS A NE2 1 
ATOM   489   N N   . CYS A 1 78  ? 149.567 107.725 107.502 1.00 32.93  ? 78  CYS A N   1 
ATOM   490   C CA  . CYS A 1 78  ? 148.603 107.741 108.594 1.00 32.93  ? 78  CYS A CA  1 
ATOM   491   C C   . CYS A 1 78  ? 147.516 106.683 108.424 1.00 32.93  ? 78  CYS A C   1 
ATOM   492   O O   . CYS A 1 78  ? 146.538 106.686 109.182 1.00 32.93  ? 78  CYS A O   1 
ATOM   493   C CB  . CYS A 1 78  ? 147.969 109.129 108.713 1.00 32.93  ? 78  CYS A CB  1 
ATOM   494   S SG  . CYS A 1 78  ? 149.151 110.468 108.957 1.00 32.93  ? 78  CYS A SG  1 
ATOM   495   N N   . ASP A 1 79  ? 147.677 105.765 107.464 1.00 34.04  ? 79  ASP A N   1 
ATOM   496   C CA  . ASP A 1 79  ? 146.617 104.814 107.138 1.00 34.04  ? 79  ASP A CA  1 
ATOM   497   C C   . ASP A 1 79  ? 146.208 103.944 108.321 1.00 34.04  ? 79  ASP A C   1 
ATOM   498   O O   . ASP A 1 79  ? 145.085 103.433 108.338 1.00 34.04  ? 79  ASP A O   1 
ATOM   499   C CB  . ASP A 1 79  ? 147.050 103.916 105.978 1.00 34.04  ? 79  ASP A CB  1 
ATOM   500   C CG  . ASP A 1 79  ? 146.852 104.571 104.625 1.00 34.04  ? 79  ASP A CG  1 
ATOM   501   O OD1 . ASP A 1 79  ? 146.109 105.572 104.543 1.00 34.04  ? 79  ASP A OD1 1 
ATOM   502   O OD2 . ASP A 1 79  ? 147.441 104.080 103.639 1.00 34.04  ? 79  ASP A OD2 1 
ATOM   503   N N   . VAL A 1 80  ? 147.089 103.762 109.306 1.00 33.08  ? 80  VAL A N   1 
ATOM   504   C CA  . VAL A 1 80  ? 146.769 102.946 110.471 1.00 33.08  ? 80  VAL A CA  1 
ATOM   505   C C   . VAL A 1 80  ? 145.694 103.562 111.356 1.00 33.08  ? 80  VAL A C   1 
ATOM   506   O O   . VAL A 1 80  ? 145.140 102.866 112.212 1.00 33.08  ? 80  VAL A O   1 
ATOM   507   C CB  . VAL A 1 80  ? 148.054 102.686 111.287 1.00 33.08  ? 80  VAL A CB  1 
ATOM   508   C CG1 . VAL A 1 80  ? 148.432 103.912 112.104 1.00 33.08  ? 80  VAL A CG1 1 
ATOM   509   C CG2 . VAL A 1 80  ? 147.900 101.460 112.176 1.00 33.08  ? 80  VAL A CG2 1 
ATOM   510   N N   . PHE A 1 81  ? 145.365 104.840 111.168 1.00 31.65  ? 81  PHE A N   1 
ATOM   511   C CA  . PHE A 1 81  ? 144.422 105.523 112.044 1.00 31.65  ? 81  PHE A CA  1 
ATOM   512   C C   . PHE A 1 81  ? 142.986 105.491 111.530 1.00 31.65  ? 81  PHE A C   1 
ATOM   513   O O   . PHE A 1 81  ? 142.151 106.248 112.032 1.00 31.65  ? 81  PHE A O   1 
ATOM   514   C CB  . PHE A 1 81  ? 144.856 106.975 112.257 1.00 31.65  ? 81  PHE A CB  1 
ATOM   515   C CG  . PHE A 1 81  ? 146.053 107.124 113.145 1.00 31.65  ? 81  PHE A CG  1 
ATOM   516   C CD1 . PHE A 1 81  ? 145.916 107.100 114.522 1.00 31.65  ? 81  PHE A CD1 1 
ATOM   517   C CD2 . PHE A 1 81  ? 147.316 107.290 112.605 1.00 31.65  ? 81  PHE A CD2 1 
ATOM   518   C CE1 . PHE A 1 81  ? 147.017 107.237 115.343 1.00 31.65  ? 81  PHE A CE1 1 
ATOM   519   C CE2 . PHE A 1 81  ? 148.419 107.426 113.420 1.00 31.65  ? 81  PHE A CE2 1 
ATOM   520   C CZ  . PHE A 1 81  ? 148.270 107.399 114.791 1.00 31.65  ? 81  PHE A CZ  1 
ATOM   521   N N   . GLN A 1 82  ? 142.679 104.645 110.552 1.00 32.89  ? 82  GLN A N   1 
ATOM   522   C CA  . GLN A 1 82  ? 141.341 104.632 109.975 1.00 32.89  ? 82  GLN A CA  1 
ATOM   523   C C   . GLN A 1 82  ? 140.320 104.097 110.973 1.00 32.89  ? 82  GLN A C   1 
ATOM   524   O O   . GLN A 1 82  ? 140.510 103.027 111.559 1.00 32.89  ? 82  GLN A O   1 
ATOM   525   C CB  . GLN A 1 82  ? 141.324 103.794 108.698 1.00 32.89  ? 82  GLN A CB  1 
ATOM   526   C CG  . GLN A 1 82  ? 141.931 104.498 107.496 1.00 32.89  ? 82  GLN A CG  1 
ATOM   527   C CD  . GLN A 1 82  ? 141.798 103.696 106.220 1.00 32.89  ? 82  GLN A CD  1 
ATOM   528   O OE1 . GLN A 1 82  ? 141.550 102.491 106.253 1.00 32.89  ? 82  GLN A OE1 1 
ATOM   529   N NE2 . GLN A 1 82  ? 141.963 104.360 105.085 1.00 32.89  ? 82  GLN A NE2 1 
ATOM   530   N N   . ASP A 1 83  ? 139.239 104.859 111.167 1.00 33.21  ? 83  ASP A N   1 
ATOM   531   C CA  . ASP A 1 83  ? 138.095 104.455 111.990 1.00 33.21  ? 83  ASP A CA  1 
ATOM   532   C C   . ASP A 1 83  ? 138.467 104.308 113.468 1.00 33.21  ? 83  ASP A C   1 
ATOM   533   O O   . ASP A 1 83  ? 137.983 103.408 114.152 1.00 33.21  ? 83  ASP A O   1 
ATOM   534   C CB  . ASP A 1 83  ? 137.463 103.164 111.462 1.00 33.21  ? 83  ASP A CB  1 
ATOM   535   C CG  . ASP A 1 83  ? 136.720 103.370 110.154 1.00 33.21  ? 83  ASP A CG  1 
ATOM   536   O OD1 . ASP A 1 83  ? 136.304 104.512 109.875 1.00 33.21  ? 83  ASP A OD1 1 
ATOM   537   O OD2 . ASP A 1 83  ? 136.557 102.389 109.402 1.00 33.21  ? 83  ASP A OD2 1 
ATOM   538   N N   . GLU A 1 84  ? 139.319 105.197 113.967 1.00 32.63  ? 84  GLU A N   1 
ATOM   539   C CA  . GLU A 1 84  ? 139.729 105.160 115.364 1.00 32.63  ? 84  GLU A CA  1 
ATOM   540   C C   . GLU A 1 84  ? 138.778 105.970 116.243 1.00 32.63  ? 84  GLU A C   1 
ATOM   541   O O   . GLU A 1 84  ? 138.002 106.800 115.766 1.00 32.63  ? 84  GLU A O   1 
ATOM   542   C CB  . GLU A 1 84  ? 141.157 105.684 115.520 1.00 32.63  ? 84  GLU A CB  1 
ATOM   543   C CG  . GLU A 1 84  ? 142.234 104.650 115.249 1.00 32.63  ? 84  GLU A CG  1 
ATOM   544   C CD  . GLU A 1 84  ? 142.574 103.820 116.471 1.00 32.63  ? 84  GLU A CD  1 
ATOM   545   O OE1 . GLU A 1 84  ? 141.806 103.858 117.453 1.00 32.63  ? 84  GLU A OE1 1 
ATOM   546   O OE2 . GLU A 1 84  ? 143.612 103.126 116.450 1.00 32.63  ? 84  GLU A OE2 1 
ATOM   547   N N   . LYS A 1 85  ? 138.849 105.707 117.549 1.00 31.00  ? 85  LYS A N   1 
ATOM   548   C CA  . LYS A 1 85  ? 138.095 106.436 118.561 1.00 31.00  ? 85  LYS A CA  1 
ATOM   549   C C   . LYS A 1 85  ? 139.029 106.812 119.704 1.00 31.00  ? 85  LYS A C   1 
ATOM   550   O O   . LYS A 1 85  ? 140.076 106.193 119.900 1.00 31.00  ? 85  LYS A O   1 
ATOM   551   C CB  . LYS A 1 85  ? 136.917 105.614 119.104 1.00 31.00  ? 85  LYS A CB  1 
ATOM   552   C CG  . LYS A 1 85  ? 136.114 104.877 118.047 1.00 31.00  ? 85  LYS A CG  1 
ATOM   553   C CD  . LYS A 1 85  ? 135.223 103.819 118.675 1.00 31.00  ? 85  LYS A CD  1 
ATOM   554   C CE  . LYS A 1 85  ? 135.150 102.570 117.810 1.00 31.00  ? 85  LYS A CE  1 
ATOM   555   N NZ  . LYS A 1 85  ? 135.124 102.894 116.358 1.00 31.00  ? 85  LYS A NZ  1 
ATOM   556   N N   . TRP A 1 86  ? 138.642 107.837 120.462 1.00 25.77  ? 86  TRP A N   1 
ATOM   557   C CA  . TRP A 1 86  ? 139.491 108.318 121.544 1.00 25.77  ? 86  TRP A CA  1 
ATOM   558   C C   . TRP A 1 86  ? 138.664 109.111 122.544 1.00 25.77  ? 86  TRP A C   1 
ATOM   559   O O   . TRP A 1 86  ? 137.598 109.639 122.220 1.00 25.77  ? 86  TRP A O   1 
ATOM   560   C CB  . TRP A 1 86  ? 140.633 109.191 121.011 1.00 25.77  ? 86  TRP A CB  1 
ATOM   561   C CG  . TRP A 1 86  ? 140.144 110.415 120.295 1.00 25.77  ? 86  TRP A CG  1 
ATOM   562   C CD1 . TRP A 1 86  ? 139.889 111.636 120.842 1.00 25.77  ? 86  TRP A CD1 1 
ATOM   563   C CD2 . TRP A 1 86  ? 139.831 110.527 118.902 1.00 25.77  ? 86  TRP A CD2 1 
ATOM   564   N NE1 . TRP A 1 86  ? 139.442 112.503 119.878 1.00 25.77  ? 86  TRP A NE1 1 
ATOM   565   C CE2 . TRP A 1 86  ? 139.400 111.847 118.677 1.00 25.77  ? 86  TRP A CE2 1 
ATOM   566   C CE3 . TRP A 1 86  ? 139.880 109.641 117.823 1.00 25.77  ? 86  TRP A CE3 1 
ATOM   567   C CZ2 . TRP A 1 86  ? 139.019 112.303 117.418 1.00 25.77  ? 86  TRP A CZ2 1 
ATOM   568   C CZ3 . TRP A 1 86  ? 139.499 110.095 116.575 1.00 25.77  ? 86  TRP A CZ3 1 
ATOM   569   C CH2 . TRP A 1 86  ? 139.074 111.412 116.383 1.00 25.77  ? 86  TRP A CH2 1 
ATOM   570   N N   . ASP A 1 87  ? 139.184 109.194 123.769 1.00 28.18  ? 87  ASP A N   1 
ATOM   571   C CA  . ASP A 1 87  ? 138.762 110.215 124.719 1.00 28.18  ? 87  ASP A CA  1 
ATOM   572   C C   . ASP A 1 87  ? 139.687 111.424 124.670 1.00 28.18  ? 87  ASP A C   1 
ATOM   573   O O   . ASP A 1 87  ? 139.229 112.563 124.793 1.00 28.18  ? 87  ASP A O   1 
ATOM   574   C CB  . ASP A 1 87  ? 138.721 109.650 126.143 1.00 28.18  ? 87  ASP A CB  1 
ATOM   575   C CG  . ASP A 1 87  ? 137.545 108.726 126.377 1.00 28.18  ? 87  ASP A CG  1 
ATOM   576   O OD1 . ASP A 1 87  ? 136.466 108.966 125.800 1.00 28.18  ? 87  ASP A OD1 1 
ATOM   577   O OD2 . ASP A 1 87  ? 137.700 107.754 127.143 1.00 28.18  ? 87  ASP A OD2 1 
ATOM   578   N N   . LEU A 1 88  ? 140.985 111.191 124.486 1.00 26.34  ? 88  LEU A N   1 
ATOM   579   C CA  . LEU A 1 88  ? 141.963 112.256 124.317 1.00 26.34  ? 88  LEU A CA  1 
ATOM   580   C C   . LEU A 1 88  ? 142.928 111.877 123.205 1.00 26.34  ? 88  LEU A C   1 
ATOM   581   O O   . LEU A 1 88  ? 143.543 110.809 123.250 1.00 26.34  ? 88  LEU A O   1 
ATOM   582   C CB  . LEU A 1 88  ? 142.731 112.523 125.619 1.00 26.34  ? 88  LEU A CB  1 
ATOM   583   C CG  . LEU A 1 88  ? 143.694 113.713 125.610 1.00 26.34  ? 88  LEU A CG  1 
ATOM   584   C CD1 . LEU A 1 88  ? 142.940 115.031 125.501 1.00 26.34  ? 88  LEU A CD1 1 
ATOM   585   C CD2 . LEU A 1 88  ? 144.579 113.703 126.843 1.00 26.34  ? 88  LEU A CD2 1 
ATOM   586   N N   . PHE A 1 89  ? 143.053 112.750 122.212 1.00 25.94  ? 89  PHE A N   1 
ATOM   587   C CA  . PHE A 1 89  ? 144.020 112.594 121.134 1.00 25.94  ? 89  PHE A CA  1 
ATOM   588   C C   . PHE A 1 89  ? 145.270 113.395 121.479 1.00 25.94  ? 89  PHE A C   1 
ATOM   589   O O   . PHE A 1 89  ? 145.181 114.588 121.781 1.00 25.94  ? 89  PHE A O   1 
ATOM   590   C CB  . PHE A 1 89  ? 143.423 113.064 119.804 1.00 25.94  ? 89  PHE A CB  1 
ATOM   591   C CG  . PHE A 1 89  ? 144.223 112.663 118.593 1.00 25.94  ? 89  PHE A CG  1 
ATOM   592   C CD1 . PHE A 1 89  ? 145.309 113.416 118.178 1.00 25.94  ? 89  PHE A CD1 1 
ATOM   593   C CD2 . PHE A 1 89  ? 143.876 111.542 117.860 1.00 25.94  ? 89  PHE A CD2 1 
ATOM   594   C CE1 . PHE A 1 89  ? 146.039 113.050 117.068 1.00 25.94  ? 89  PHE A CE1 1 
ATOM   595   C CE2 . PHE A 1 89  ? 144.603 111.175 116.747 1.00 25.94  ? 89  PHE A CE2 1 
ATOM   596   C CZ  . PHE A 1 89  ? 145.686 111.929 116.352 1.00 25.94  ? 89  PHE A CZ  1 
ATOM   597   N N   . VAL A 1 90  ? 146.427 112.742 121.435 1.00 27.27  ? 90  VAL A N   1 
ATOM   598   C CA  . VAL A 1 90  ? 147.699 113.360 121.800 1.00 27.27  ? 90  VAL A CA  1 
ATOM   599   C C   . VAL A 1 90  ? 148.513 113.579 120.531 1.00 27.27  ? 90  VAL A C   1 
ATOM   600   O O   . VAL A 1 90  ? 148.887 112.618 119.850 1.00 27.27  ? 90  VAL A O   1 
ATOM   601   C CB  . VAL A 1 90  ? 148.475 112.504 122.814 1.00 27.27  ? 90  VAL A CB  1 
ATOM   602   C CG1 . VAL A 1 90  ? 149.785 113.176 123.186 1.00 27.27  ? 90  VAL A CG1 1 
ATOM   603   C CG2 . VAL A 1 90  ? 147.633 112.258 124.053 1.00 27.27  ? 90  VAL A CG2 1 
ATOM   604   N N   . GLU A 1 91  ? 148.799 114.842 120.223 1.00 28.92  ? 91  GLU A N   1 
ATOM   605   C CA  . GLU A 1 91  ? 149.570 115.219 119.045 1.00 28.92  ? 91  GLU A CA  1 
ATOM   606   C C   . GLU A 1 91  ? 151.019 115.482 119.435 1.00 28.92  ? 91  GLU A C   1 
ATOM   607   O O   . GLU A 1 91  ? 151.290 116.274 120.342 1.00 28.92  ? 91  GLU A O   1 
ATOM   608   C CB  . GLU A 1 91  ? 148.976 116.461 118.379 1.00 28.92  ? 91  GLU A CB  1 
ATOM   609   C CG  . GLU A 1 91  ? 147.961 116.169 117.294 1.00 28.92  ? 91  GLU A CG  1 
ATOM   610   C CD  . GLU A 1 91  ? 147.461 117.427 116.612 1.00 28.92  ? 91  GLU A CD  1 
ATOM   611   O OE1 . GLU A 1 91  ? 147.757 118.531 117.108 1.00 28.92  ? 91  GLU A OE1 1 
ATOM   612   O OE2 . GLU A 1 91  ? 146.772 117.312 115.580 1.00 28.92  ? 91  GLU A OE2 1 
ATOM   613   N N   . ARG A 1 92  ? 151.942 114.823 118.744 1.00 30.60  ? 92  ARG A N   1 
ATOM   614   C CA  . ARG A 1 92  ? 153.365 114.983 119.000 1.00 30.60  ? 92  ARG A CA  1 
ATOM   615   C C   . ARG A 1 92  ? 153.943 116.107 118.146 1.00 30.60  ? 92  ARG A C   1 
ATOM   616   O O   . ARG A 1 92  ? 153.417 116.452 117.087 1.00 30.60  ? 92  ARG A O   1 
ATOM   617   C CB  . ARG A 1 92  ? 154.115 113.679 118.724 1.00 30.60  ? 92  ARG A CB  1 
ATOM   618   C CG  . ARG A 1 92  ? 153.506 112.453 119.378 1.00 30.60  ? 92  ARG A CG  1 
ATOM   619   C CD  . ARG A 1 92  ? 153.366 112.642 120.874 1.00 30.60  ? 92  ARG A CD  1 
ATOM   620   N NE  . ARG A 1 92  ? 153.219 111.376 121.583 1.00 30.60  ? 92  ARG A NE  1 
ATOM   621   C CZ  . ARG A 1 92  ? 153.188 111.258 122.902 1.00 30.60  ? 92  ARG A CZ  1 
ATOM   622   N NH1 . ARG A 1 92  ? 153.286 112.312 123.693 1.00 30.60  ? 92  ARG A NH1 1 
ATOM   623   N NH2 . ARG A 1 92  ? 153.057 110.051 123.442 1.00 30.60  ? 92  ARG A NH2 1 
ATOM   624   N N   . SER A 1 93  ? 155.049 116.675 118.624 1.00 33.11  ? 93  SER A N   1 
ATOM   625   C CA  . SER A 1 93  ? 155.702 117.773 117.924 1.00 33.11  ? 93  SER A CA  1 
ATOM   626   C C   . SER A 1 93  ? 156.567 117.311 116.758 1.00 33.11  ? 93  SER A C   1 
ATOM   627   O O   . SER A 1 93  ? 157.042 118.154 115.992 1.00 33.11  ? 93  SER A O   1 
ATOM   628   C CB  . SER A 1 93  ? 156.548 118.591 118.903 1.00 33.11  ? 93  SER A CB  1 
ATOM   629   O OG  . SER A 1 93  ? 157.821 118.004 119.099 1.00 33.11  ? 93  SER A OG  1 
ATOM   630   N N   . SER A 1 94  ? 156.781 116.008 116.602 1.00 32.59  ? 94  SER A N   1 
ATOM   631   C CA  . SER A 1 94  ? 157.538 115.471 115.480 1.00 32.59  ? 94  SER A CA  1 
ATOM   632   C C   . SER A 1 94  ? 156.646 115.034 114.322 1.00 32.59  ? 94  SER A C   1 
ATOM   633   O O   . SER A 1 94  ? 157.136 114.396 113.386 1.00 32.59  ? 94  SER A O   1 
ATOM   634   C CB  . SER A 1 94  ? 158.408 114.299 115.944 1.00 32.59  ? 94  SER A CB  1 
ATOM   635   O OG  . SER A 1 94  ? 157.621 113.239 116.454 1.00 32.59  ? 94  SER A OG  1 
ATOM   636   N N   . ALA A 1 95  ? 155.356 115.360 114.367 1.00 32.02  ? 95  ALA A N   1 
ATOM   637   C CA  . ALA A 1 95  ? 154.445 115.021 113.283 1.00 32.02  ? 95  ALA A CA  1 
ATOM   638   C C   . ALA A 1 95  ? 154.784 115.808 112.020 1.00 32.02  ? 95  ALA A C   1 
ATOM   639   O O   . ALA A 1 95  ? 155.210 116.964 112.077 1.00 32.02  ? 95  ALA A O   1 
ATOM   640   C CB  . ALA A 1 95  ? 153.001 115.297 113.698 1.00 32.02  ? 95  ALA A CB  1 
ATOM   641   N N   . PHE A 1 96  ? 154.589 115.166 110.868 1.00 30.24  ? 96  PHE A N   1 
ATOM   642   C CA  . PHE A 1 96  ? 154.883 115.773 109.577 1.00 30.24  ? 96  PHE A CA  1 
ATOM   643   C C   . PHE A 1 96  ? 153.850 115.324 108.550 1.00 30.24  ? 96  PHE A C   1 
ATOM   644   O O   . PHE A 1 96  ? 153.101 114.369 108.763 1.00 30.24  ? 96  PHE A O   1 
ATOM   645   C CB  . PHE A 1 96  ? 156.305 115.431 109.106 1.00 30.24  ? 96  PHE A CB  1 
ATOM   646   C CG  . PHE A 1 96  ? 156.533 113.965 108.856 1.00 30.24  ? 96  PHE A CG  1 
ATOM   647   C CD1 . PHE A 1 96  ? 156.921 113.124 109.885 1.00 30.24  ? 96  PHE A CD1 1 
ATOM   648   C CD2 . PHE A 1 96  ? 156.381 113.431 107.588 1.00 30.24  ? 96  PHE A CD2 1 
ATOM   649   C CE1 . PHE A 1 96  ? 157.138 111.781 109.657 1.00 30.24  ? 96  PHE A CE1 1 
ATOM   650   C CE2 . PHE A 1 96  ? 156.595 112.088 107.355 1.00 30.24  ? 96  PHE A CE2 1 
ATOM   651   C CZ  . PHE A 1 96  ? 156.976 111.262 108.391 1.00 30.24  ? 96  PHE A CZ  1 
ATOM   652   N N   . SER A 1 97  ? 153.819 116.031 107.423 1.00 29.27  ? 97  SER A N   1 
ATOM   653   C CA  . SER A 1 97  ? 152.916 115.742 106.317 1.00 29.27  ? 97  SER A CA  1 
ATOM   654   C C   . SER A 1 97  ? 153.710 115.206 105.133 1.00 29.27  ? 97  SER A C   1 
ATOM   655   O O   . SER A 1 97  ? 154.821 115.669 104.863 1.00 29.27  ? 97  SER A O   1 
ATOM   656   C CB  . SER A 1 97  ? 152.143 116.993 105.898 1.00 29.27  ? 97  SER A CB  1 
ATOM   657   O OG  . SER A 1 97  ? 151.114 117.294 106.820 1.00 29.27  ? 97  SER A OG  1 
ATOM   658   N N   . ASN A 1 98  ? 153.145 114.223 104.433 1.00 29.45  ? 98  ASN A N   1 
ATOM   659   C CA  . ASN A 1 98  ? 153.857 113.550 103.350 1.00 29.45  ? 98  ASN A CA  1 
ATOM   660   C C   . ASN A 1 98  ? 152.938 113.281 102.162 1.00 29.45  ? 98  ASN A C   1 
ATOM   661   O O   . ASN A 1 98  ? 152.966 112.198 101.571 1.00 29.45  ? 98  ASN A O   1 
ATOM   662   C CB  . ASN A 1 98  ? 154.491 112.252 103.845 1.00 29.45  ? 98  ASN A CB  1 
ATOM   663   C CG  . ASN A 1 98  ? 155.728 111.872 103.062 1.00 29.45  ? 98  ASN A CG  1 
ATOM   664   O OD1 . ASN A 1 98  ? 156.515 112.730 102.672 1.00 29.45  ? 98  ASN A OD1 1 
ATOM   665   N ND2 . ASN A 1 98  ? 155.910 110.579 102.835 1.00 29.45  ? 98  ASN A ND2 1 
ATOM   666   N N   . CYS A 1 99  ? 152.119 114.256 101.786 1.00 27.50  ? 99  CYS A N   1 
ATOM   667   C CA  . CYS A 1 99  ? 151.167 114.086 100.690 1.00 27.50  ? 99  CYS A CA  1 
ATOM   668   C C   . CYS A 1 99  ? 151.130 115.382 99.883  1.00 27.50  ? 99  CYS A C   1 
ATOM   669   O O   . CYS A 1 99  ? 152.028 116.225 99.978  1.00 27.50  ? 99  CYS A O   1 
ATOM   670   C CB  . CYS A 1 99  ? 149.790 113.666 101.229 1.00 27.50  ? 99  CYS A CB  1 
ATOM   671   S SG  . CYS A 1 99  ? 148.657 112.962 99.991  1.00 27.50  ? 99  CYS A SG  1 
ATOM   672   N N   . TYR A 1 100 ? 150.099 115.533 99.056  1.00 24.09  ? 100 TYR A N   1 
ATOM   673   C CA  . TYR A 1 100 ? 149.955 116.726 98.232  1.00 24.09  ? 100 TYR A CA  1 
ATOM   674   C C   . TYR A 1 100 ? 149.784 117.960 99.116  1.00 24.09  ? 100 TYR A C   1 
ATOM   675   O O   . TYR A 1 100 ? 149.021 117.917 100.089 1.00 24.09  ? 100 TYR A O   1 
ATOM   676   C CB  . TYR A 1 100 ? 148.762 116.581 97.286  1.00 24.09  ? 100 TYR A CB  1 
ATOM   677   C CG  . TYR A 1 100 ? 148.828 117.469 96.061  1.00 24.09  ? 100 TYR A CG  1 
ATOM   678   C CD1 . TYR A 1 100 ? 149.491 117.053 94.913  1.00 24.09  ? 100 TYR A CD1 1 
ATOM   679   C CD2 . TYR A 1 100 ? 148.231 118.721 96.053  1.00 24.09  ? 100 TYR A CD2 1 
ATOM   680   C CE1 . TYR A 1 100 ? 149.557 117.860 93.796  1.00 24.09  ? 100 TYR A CE1 1 
ATOM   681   C CE2 . TYR A 1 100 ? 148.292 119.535 94.943  1.00 24.09  ? 100 TYR A CE2 1 
ATOM   682   C CZ  . TYR A 1 100 ? 148.954 119.099 93.817  1.00 24.09  ? 100 TYR A CZ  1 
ATOM   683   O OH  . TYR A 1 100 ? 149.015 119.907 92.709  1.00 24.09  ? 100 TYR A OH  1 
ATOM   684   N N   . PRO A 1 101 ? 150.479 119.060 98.828  1.00 22.77  ? 101 PRO A N   1 
ATOM   685   C CA  . PRO A 1 101 ? 150.358 120.254 99.675  1.00 22.77  ? 101 PRO A CA  1 
ATOM   686   C C   . PRO A 1 101 ? 148.938 120.803 99.673  1.00 22.77  ? 101 PRO A C   1 
ATOM   687   O O   . PRO A 1 101 ? 148.252 120.800 98.650  1.00 22.77  ? 101 PRO A O   1 
ATOM   688   C CB  . PRO A 1 101 ? 151.347 121.240 99.045  1.00 22.77  ? 101 PRO A CB  1 
ATOM   689   C CG  . PRO A 1 101 ? 151.559 120.745 97.658  1.00 22.77  ? 101 PRO A CG  1 
ATOM   690   C CD  . PRO A 1 101 ? 151.420 119.260 97.715  1.00 22.77  ? 101 PRO A CD  1 
ATOM   691   N N   . TYR A 1 102 ? 148.507 121.286 100.836 1.00 23.19  ? 102 TYR A N   1 
ATOM   692   C CA  . TYR A 1 102 ? 147.135 121.734 101.018 1.00 23.19  ? 102 TYR A CA  1 
ATOM   693   C C   . TYR A 1 102 ? 147.089 122.784 102.118 1.00 23.19  ? 102 TYR A C   1 
ATOM   694   O O   . TYR A 1 102 ? 148.056 122.994 102.850 1.00 23.19  ? 102 TYR A O   1 
ATOM   695   C CB  . TYR A 1 102 ? 146.201 120.563 101.349 1.00 23.19  ? 102 TYR A CB  1 
ATOM   696   C CG  . TYR A 1 102 ? 146.395 120.005 102.742 1.00 23.19  ? 102 TYR A CG  1 
ATOM   697   C CD1 . TYR A 1 102 ? 147.321 119.000 102.981 1.00 23.19  ? 102 TYR A CD1 1 
ATOM   698   C CD2 . TYR A 1 102 ? 145.658 120.485 103.816 1.00 23.19  ? 102 TYR A CD2 1 
ATOM   699   C CE1 . TYR A 1 102 ? 147.509 118.491 104.245 1.00 23.19  ? 102 TYR A CE1 1 
ATOM   700   C CE2 . TYR A 1 102 ? 145.842 119.982 105.088 1.00 23.19  ? 102 TYR A CE2 1 
ATOM   701   C CZ  . TYR A 1 102 ? 146.768 118.984 105.296 1.00 23.19  ? 102 TYR A CZ  1 
ATOM   702   O OH  . TYR A 1 102 ? 146.955 118.474 106.558 1.00 23.19  ? 102 TYR A OH  1 
ATOM   703   N N   . ASP A 1 103 ? 145.938 123.443 102.226 1.00 24.81  ? 103 ASP A N   1 
ATOM   704   C CA  . ASP A 1 103 ? 145.673 124.366 103.318 1.00 24.81  ? 103 ASP A CA  1 
ATOM   705   C C   . ASP A 1 103 ? 144.194 124.300 103.665 1.00 24.81  ? 103 ASP A C   1 
ATOM   706   O O   . ASP A 1 103 ? 143.363 123.893 102.850 1.00 24.81  ? 103 ASP A O   1 
ATOM   707   C CB  . ASP A 1 103 ? 146.080 125.800 102.964 1.00 24.81  ? 103 ASP A CB  1 
ATOM   708   C CG  . ASP A 1 103 ? 145.309 126.347 101.781 1.00 24.81  ? 103 ASP A CG  1 
ATOM   709   O OD1 . ASP A 1 103 ? 145.725 126.096 100.631 1.00 24.81  ? 103 ASP A OD1 1 
ATOM   710   O OD2 . ASP A 1 103 ? 144.283 127.021 102.000 1.00 24.81  ? 103 ASP A OD2 1 
ATOM   711   N N   . VAL A 1 104 ? 143.872 124.702 104.889 1.00 24.16  ? 104 VAL A N   1 
ATOM   712   C CA  . VAL A 1 104 ? 142.493 124.690 105.371 1.00 24.16  ? 104 VAL A CA  1 
ATOM   713   C C   . VAL A 1 104 ? 142.108 126.089 105.835 1.00 24.16  ? 104 VAL A C   1 
ATOM   714   O O   . VAL A 1 104 ? 142.661 126.580 106.828 1.00 24.16  ? 104 VAL A O   1 
ATOM   715   C CB  . VAL A 1 104 ? 142.302 123.672 106.509 1.00 24.16  ? 104 VAL A CB  1 
ATOM   716   C CG1 . VAL A 1 104 ? 140.833 123.565 106.886 1.00 24.16  ? 104 VAL A CG1 1 
ATOM   717   C CG2 . VAL A 1 104 ? 142.855 122.314 106.124 1.00 24.16  ? 104 VAL A CG2 1 
ATOM   718   N N   . PRO A 1 105 ? 141.193 126.772 105.152 1.00 24.87  ? 105 PRO A N   1 
ATOM   719   C CA  . PRO A 1 105 ? 140.617 127.993 105.729 1.00 24.87  ? 105 PRO A CA  1 
ATOM   720   C C   . PRO A 1 105 ? 139.896 127.664 107.029 1.00 24.87  ? 105 PRO A C   1 
ATOM   721   O O   . PRO A 1 105 ? 139.048 126.770 107.078 1.00 24.87  ? 105 PRO A O   1 
ATOM   722   C CB  . PRO A 1 105 ? 139.652 128.483 104.643 1.00 24.87  ? 105 PRO A CB  1 
ATOM   723   C CG  . PRO A 1 105 ? 140.108 127.823 103.390 1.00 24.87  ? 105 PRO A CG  1 
ATOM   724   C CD  . PRO A 1 105 ? 140.710 126.516 103.786 1.00 24.87  ? 105 PRO A CD  1 
ATOM   725   N N   . ASP A 1 106 ? 140.250 128.390 108.088 1.00 27.18  ? 106 ASP A N   1 
ATOM   726   C CA  . ASP A 1 106 ? 139.795 128.095 109.448 1.00 27.18  ? 106 ASP A CA  1 
ATOM   727   C C   . ASP A 1 106 ? 140.176 126.667 109.850 1.00 27.18  ? 106 ASP A C   1 
ATOM   728   O O   . ASP A 1 106 ? 139.332 125.818 110.140 1.00 27.18  ? 106 ASP A O   1 
ATOM   729   C CB  . ASP A 1 106 ? 138.289 128.339 109.597 1.00 27.18  ? 106 ASP A CB  1 
ATOM   730   C CG  . ASP A 1 106 ? 137.917 128.863 110.974 1.00 27.18  ? 106 ASP A CG  1 
ATOM   731   O OD1 . ASP A 1 106 ? 138.808 128.937 111.848 1.00 27.18  ? 106 ASP A OD1 1 
ATOM   732   O OD2 . ASP A 1 106 ? 136.734 129.200 111.183 1.00 27.18  ? 106 ASP A OD2 1 
ATOM   733   N N   . TYR A 1 107 ? 141.488 126.426 109.861 1.00 24.95  ? 107 TYR A N   1 
ATOM   734   C CA  . TYR A 1 107 ? 142.027 125.137 110.284 1.00 24.95  ? 107 TYR A CA  1 
ATOM   735   C C   . TYR A 1 107 ? 141.646 124.819 111.726 1.00 24.95  ? 107 TYR A C   1 
ATOM   736   O O   . TYR A 1 107 ? 141.265 123.683 112.044 1.00 24.95  ? 107 TYR A O   1 
ATOM   737   C CB  . TYR A 1 107 ? 143.547 125.156 110.109 1.00 24.95  ? 107 TYR A CB  1 
ATOM   738   C CG  . TYR A 1 107 ? 144.282 123.901 110.514 1.00 24.95  ? 107 TYR A CG  1 
ATOM   739   C CD1 . TYR A 1 107 ? 144.669 123.691 111.831 1.00 24.95  ? 107 TYR A CD1 1 
ATOM   740   C CD2 . TYR A 1 107 ? 144.618 122.940 109.573 1.00 24.95  ? 107 TYR A CD2 1 
ATOM   741   C CE1 . TYR A 1 107 ? 145.350 122.553 112.200 1.00 24.95  ? 107 TYR A CE1 1 
ATOM   742   C CE2 . TYR A 1 107 ? 145.301 121.800 109.932 1.00 24.95  ? 107 TYR A CE2 1 
ATOM   743   C CZ  . TYR A 1 107 ? 145.663 121.610 111.247 1.00 24.95  ? 107 TYR A CZ  1 
ATOM   744   O OH  . TYR A 1 107 ? 146.343 120.474 111.606 1.00 24.95  ? 107 TYR A OH  1 
ATOM   745   N N   . ALA A 1 108 ? 141.733 125.817 112.609 1.00 25.41  ? 108 ALA A N   1 
ATOM   746   C CA  . ALA A 1 108 ? 141.498 125.587 114.030 1.00 25.41  ? 108 ALA A CA  1 
ATOM   747   C C   . ALA A 1 108 ? 140.078 125.100 114.295 1.00 25.41  ? 108 ALA A C   1 
ATOM   748   O O   . ALA A 1 108 ? 139.868 124.218 115.132 1.00 25.41  ? 108 ALA A O   1 
ATOM   749   C CB  . ALA A 1 108 ? 141.788 126.864 114.818 1.00 25.41  ? 108 ALA A CB  1 
ATOM   750   N N   . SER A 1 109 ? 139.092 125.653 113.585 1.00 25.70  ? 109 SER A N   1 
ATOM   751   C CA  . SER A 1 109 ? 137.701 125.267 113.814 1.00 25.70  ? 109 SER A CA  1 
ATOM   752   C C   . SER A 1 109 ? 137.444 123.815 113.418 1.00 25.70  ? 109 SER A C   1 
ATOM   753   O O   . SER A 1 109 ? 136.804 123.063 114.163 1.00 25.70  ? 109 SER A O   1 
ATOM   754   C CB  . SER A 1 109 ? 136.770 126.207 113.050 1.00 25.70  ? 109 SER A CB  1 
ATOM   755   O OG  . SER A 1 109 ? 136.553 127.402 113.774 1.00 25.70  ? 109 SER A OG  1 
ATOM   756   N N   . LEU A 1 110 ? 137.918 123.407 112.237 1.00 24.27  ? 110 LEU A N   1 
ATOM   757   C CA  . LEU A 1 110 ? 137.740 122.021 111.812 1.00 24.27  ? 110 LEU A CA  1 
ATOM   758   C C   . LEU A 1 110 ? 138.475 121.065 112.742 1.00 24.27  ? 110 LEU A C   1 
ATOM   759   O O   . LEU A 1 110 ? 137.944 120.005 113.102 1.00 24.27  ? 110 LEU A O   1 
ATOM   760   C CB  . LEU A 1 110 ? 138.215 121.844 110.369 1.00 24.27  ? 110 LEU A CB  1 
ATOM   761   C CG  . LEU A 1 110 ? 138.061 120.452 109.745 1.00 24.27  ? 110 LEU A CG  1 
ATOM   762   C CD1 . LEU A 1 110 ? 136.604 120.020 109.710 1.00 24.27  ? 110 LEU A CD1 1 
ATOM   763   C CD2 . LEU A 1 110 ? 138.664 120.407 108.352 1.00 24.27  ? 110 LEU A CD2 1 
ATOM   764   N N   . ARG A 1 111 ? 139.696 121.427 113.146 1.00 24.89  ? 111 ARG A N   1 
ATOM   765   C CA  . ARG A 1 111 ? 140.436 120.608 114.102 1.00 24.89  ? 111 ARG A CA  1 
ATOM   766   C C   . ARG A 1 111 ? 139.654 120.448 115.401 1.00 24.89  ? 111 ARG A C   1 
ATOM   767   O O   . ARG A 1 111 ? 139.505 119.335 115.919 1.00 24.89  ? 111 ARG A O   1 
ATOM   768   C CB  . ARG A 1 111 ? 141.810 121.232 114.361 1.00 24.89  ? 111 ARG A CB  1 
ATOM   769   C CG  . ARG A 1 111 ? 142.672 120.526 115.400 1.00 24.89  ? 111 ARG A CG  1 
ATOM   770   C CD  . ARG A 1 111 ? 143.996 121.259 115.581 1.00 24.89  ? 111 ARG A CD  1 
ATOM   771   N NE  . ARG A 1 111 ? 144.862 120.645 116.581 1.00 24.89  ? 111 ARG A NE  1 
ATOM   772   C CZ  . ARG A 1 111 ? 144.877 120.974 117.865 1.00 24.89  ? 111 ARG A CZ  1 
ATOM   773   N NH1 . ARG A 1 111 ? 144.069 121.900 118.351 1.00 24.89  ? 111 ARG A NH1 1 
ATOM   774   N NH2 . ARG A 1 111 ? 145.726 120.359 118.682 1.00 24.89  ? 111 ARG A NH2 1 
ATOM   775   N N   . SER A 1 112 ? 139.118 121.554 115.922 1.00 25.96  ? 112 SER A N   1 
ATOM   776   C CA  . SER A 1 112 ? 138.385 121.515 117.181 1.00 25.96  ? 112 SER A CA  1 
ATOM   777   C C   . SER A 1 112 ? 137.135 120.651 117.073 1.00 25.96  ? 112 SER A C   1 
ATOM   778   O O   . SER A 1 112 ? 136.846 119.855 117.974 1.00 25.96  ? 112 SER A O   1 
ATOM   779   C CB  . SER A 1 112 ? 138.025 122.936 117.614 1.00 25.96  ? 112 SER A CB  1 
ATOM   780   O OG  . SER A 1 112 ? 136.985 122.938 118.573 1.00 25.96  ? 112 SER A OG  1 
ATOM   781   N N   . LEU A 1 113 ? 136.389 120.775 115.972 1.00 25.70  ? 113 LEU A N   1 
ATOM   782   C CA  . LEU A 1 113 ? 135.142 120.023 115.860 1.00 25.70  ? 113 LEU A CA  1 
ATOM   783   C C   . LEU A 1 113 ? 135.405 118.531 115.665 1.00 25.70  ? 113 LEU A C   1 
ATOM   784   O O   . LEU A 1 113 ? 134.706 117.693 116.253 1.00 25.70  ? 113 LEU A O   1 
ATOM   785   C CB  . LEU A 1 113 ? 134.271 120.599 114.740 1.00 25.70  ? 113 LEU A CB  1 
ATOM   786   C CG  . LEU A 1 113 ? 134.387 120.186 113.273 1.00 25.70  ? 113 LEU A CG  1 
ATOM   787   C CD1 . LEU A 1 113 ? 133.460 119.025 112.960 1.00 25.70  ? 113 LEU A CD1 1 
ATOM   788   C CD2 . LEU A 1 113 ? 134.070 121.375 112.383 1.00 25.70  ? 113 LEU A CD2 1 
ATOM   789   N N   . ILE A 1 114 ? 136.425 118.173 114.877 1.00 25.45  ? 114 ILE A N   1 
ATOM   790   C CA  . ILE A 1 114 ? 136.775 116.761 114.739 1.00 25.45  ? 114 ILE A CA  1 
ATOM   791   C C   . ILE A 1 114 ? 137.241 116.191 116.073 1.00 25.45  ? 114 ILE A C   1 
ATOM   792   O O   . ILE A 1 114 ? 136.854 115.080 116.456 1.00 25.45  ? 114 ILE A O   1 
ATOM   793   C CB  . ILE A 1 114 ? 137.838 116.565 113.643 1.00 25.45  ? 114 ILE A CB  1 
ATOM   794   C CG1 . ILE A 1 114 ? 137.296 117.018 112.289 1.00 25.45  ? 114 ILE A CG1 1 
ATOM   795   C CG2 . ILE A 1 114 ? 138.263 115.110 113.574 1.00 25.45  ? 114 ILE A CG2 1 
ATOM   796   C CD1 . ILE A 1 114 ? 136.072 116.268 111.858 1.00 25.45  ? 114 ILE A CD1 1 
ATOM   797   N N   . ALA A 1 115 ? 138.078 116.936 116.802 1.00 25.36  ? 115 ALA A N   1 
ATOM   798   C CA  . ALA A 1 115 ? 138.569 116.450 118.087 1.00 25.36  ? 115 ALA A CA  1 
ATOM   799   C C   . ALA A 1 115 ? 137.433 116.276 119.084 1.00 25.36  ? 115 ALA A C   1 
ATOM   800   O O   . ALA A 1 115 ? 137.420 115.312 119.858 1.00 25.36  ? 115 ALA A O   1 
ATOM   801   C CB  . ALA A 1 115 ? 139.624 117.404 118.642 1.00 25.36  ? 115 ALA A CB  1 
ATOM   802   N N   . SER A 1 116 ? 136.470 117.200 119.083 1.00 27.62  ? 116 SER A N   1 
ATOM   803   C CA  . SER A 1 116 ? 135.347 117.100 120.006 1.00 27.62  ? 116 SER A CA  1 
ATOM   804   C C   . SER A 1 116 ? 134.416 115.950 119.644 1.00 27.62  ? 116 SER A C   1 
ATOM   805   O O   . SER A 1 116 ? 133.791 115.363 120.534 1.00 27.62  ? 116 SER A O   1 
ATOM   806   C CB  . SER A 1 116 ? 134.580 118.419 120.039 1.00 27.62  ? 116 SER A CB  1 
ATOM   807   O OG  . SER A 1 116 ? 133.372 118.289 120.761 1.00 27.62  ? 116 SER A OG  1 
ATOM   808   N N   . SER A 1 117 ? 134.300 115.619 118.355 1.00 28.31  ? 117 SER A N   1 
ATOM   809   C CA  . SER A 1 117 ? 133.458 114.492 117.964 1.00 28.31  ? 117 SER A CA  1 
ATOM   810   C C   . SER A 1 117 ? 133.985 113.175 118.529 1.00 28.31  ? 117 SER A C   1 
ATOM   811   O O   . SER A 1 117 ? 133.207 112.341 119.004 1.00 28.31  ? 117 SER A O   1 
ATOM   812   C CB  . SER A 1 117 ? 133.352 114.420 116.443 1.00 28.31  ? 117 SER A CB  1 
ATOM   813   O OG  . SER A 1 117 ? 132.508 113.357 116.046 1.00 28.31  ? 117 SER A OG  1 
ATOM   814   N N   . GLY A 1 118 ? 135.297 112.963 118.473 1.00 26.87  ? 118 GLY A N   1 
ATOM   815   C CA  . GLY A 1 118 ? 135.919 111.818 119.108 1.00 26.87  ? 118 GLY A CA  1 
ATOM   816   C C   . GLY A 1 118 ? 135.986 110.540 118.301 1.00 26.87  ? 118 GLY A C   1 
ATOM   817   O O   . GLY A 1 118 ? 136.280 109.487 118.877 1.00 26.87  ? 118 GLY A O   1 
ATOM   818   N N   . THR A 1 119 ? 135.731 110.587 116.994 1.00 29.15  ? 119 THR A N   1 
ATOM   819   C CA  . THR A 1 119 ? 135.763 109.381 116.178 1.00 29.15  ? 119 THR A CA  1 
ATOM   820   C C   . THR A 1 119 ? 136.121 109.742 114.742 1.00 29.15  ? 119 THR A C   1 
ATOM   821   O O   . THR A 1 119 ? 135.990 110.893 114.319 1.00 29.15  ? 119 THR A O   1 
ATOM   822   C CB  . THR A 1 119 ? 134.421 108.636 116.223 1.00 29.15  ? 119 THR A CB  1 
ATOM   823   O OG1 . THR A 1 119 ? 134.530 107.397 115.515 1.00 29.15  ? 119 THR A OG1 1 
ATOM   824   C CG2 . THR A 1 119 ? 133.317 109.474 115.600 1.00 29.15  ? 119 THR A CG2 1 
ATOM   825   N N   . LEU A 1 120 ? 136.589 108.738 113.998 1.00 28.14  ? 120 LEU A N   1 
ATOM   826   C CA  . LEU A 1 120 ? 136.894 108.870 112.578 1.00 28.14  ? 120 LEU A CA  1 
ATOM   827   C C   . LEU A 1 120 ? 136.137 107.840 111.741 1.00 28.14  ? 120 LEU A C   1 
ATOM   828   O O   . LEU A 1 120 ? 136.635 107.384 110.712 1.00 28.14  ? 120 LEU A O   1 
ATOM   829   C CB  . LEU A 1 120 ? 138.397 108.751 112.326 1.00 28.14  ? 120 LEU A CB  1 
ATOM   830   C CG  . LEU A 1 120 ? 139.306 109.907 112.749 1.00 28.14  ? 120 LEU A CG  1 
ATOM   831   C CD1 . LEU A 1 120 ? 140.736 109.651 112.302 1.00 28.14  ? 120 LEU A CD1 1 
ATOM   832   C CD2 . LEU A 1 120 ? 138.798 111.228 112.200 1.00 28.14  ? 120 LEU A CD2 1 
ATOM   833   N N   . ASP A 1 121 ? 134.935 107.464 112.172 1.00 29.59  ? 121 ASP A N   1 
ATOM   834   C CA  . ASP A 1 121 ? 134.150 106.462 111.458 1.00 29.59  ? 121 ASP A CA  1 
ATOM   835   C C   . ASP A 1 121 ? 133.672 107.017 110.119 1.00 29.59  ? 121 ASP A C   1 
ATOM   836   O O   . ASP A 1 121 ? 133.005 108.054 110.071 1.00 29.59  ? 121 ASP A O   1 
ATOM   837   C CB  . ASP A 1 121 ? 132.966 106.019 112.311 1.00 29.59  ? 121 ASP A CB  1 
ATOM   838   C CG  . ASP A 1 121 ? 132.377 104.703 111.850 1.00 29.59  ? 121 ASP A CG  1 
ATOM   839   O OD1 . ASP A 1 121 ? 133.088 103.678 111.909 1.00 29.59  ? 121 ASP A OD1 1 
ATOM   840   O OD2 . ASP A 1 121 ? 131.203 104.693 111.428 1.00 29.59  ? 121 ASP A OD2 1 
ATOM   841   N N   . PHE A 1 122 ? 134.001 106.314 109.037 1.00 23.72  ? 122 PHE A N   1 
ATOM   842   C CA  . PHE A 1 122 ? 133.751 106.769 107.675 1.00 23.72  ? 122 PHE A CA  1 
ATOM   843   C C   . PHE A 1 122 ? 132.866 105.758 106.960 1.00 23.72  ? 122 PHE A C   1 
ATOM   844   O O   . PHE A 1 122 ? 133.099 104.549 107.058 1.00 23.72  ? 122 PHE A O   1 
ATOM   845   C CB  . PHE A 1 122 ? 135.079 106.959 106.926 1.00 23.72  ? 122 PHE A CB  1 
ATOM   846   C CG  . PHE A 1 122 ? 134.939 107.584 105.565 1.00 23.72  ? 122 PHE A CG  1 
ATOM   847   C CD1 . PHE A 1 122 ? 134.876 108.959 105.420 1.00 23.72  ? 122 PHE A CD1 1 
ATOM   848   C CD2 . PHE A 1 122 ? 134.898 106.796 104.427 1.00 23.72  ? 122 PHE A CD2 1 
ATOM   849   C CE1 . PHE A 1 122 ? 134.756 109.535 104.172 1.00 23.72  ? 122 PHE A CE1 1 
ATOM   850   C CE2 . PHE A 1 122 ? 134.779 107.366 103.176 1.00 23.72  ? 122 PHE A CE2 1 
ATOM   851   C CZ  . PHE A 1 122 ? 134.711 108.736 103.048 1.00 23.72  ? 122 PHE A CZ  1 
ATOM   852   N N   . ILE A 1 123 ? 131.852 106.250 106.250 1.00 24.56  ? 123 ILE A N   1 
ATOM   853   C CA  . ILE A 1 123 ? 130.941 105.416 105.471 1.00 24.56  ? 123 ILE A CA  1 
ATOM   854   C C   . ILE A 1 123 ? 131.087 105.801 104.006 1.00 24.56  ? 123 ILE A C   1 
ATOM   855   O O   . ILE A 1 123 ? 130.901 106.970 103.645 1.00 24.56  ? 123 ILE A O   1 
ATOM   856   C CB  . ILE A 1 123 ? 129.481 105.570 105.928 1.00 24.56  ? 123 ILE A CB  1 
ATOM   857   C CG1 . ILE A 1 123 ? 129.352 105.343 107.436 1.00 24.56  ? 123 ILE A CG1 1 
ATOM   858   C CG2 . ILE A 1 123 ? 128.576 104.628 105.148 1.00 24.56  ? 123 ILE A CG2 1 
ATOM   859   C CD1 . ILE A 1 123 ? 129.356 103.894 107.841 1.00 24.56  ? 123 ILE A CD1 1 
ATOM   860   N N   . THR A 1 124 ? 131.417 104.820 103.169 1.00 26.64  ? 124 THR A N   1 
ATOM   861   C CA  . THR A 1 124 ? 131.551 105.034 101.735 1.00 26.64  ? 124 THR A CA  1 
ATOM   862   C C   . THR A 1 124 ? 130.180 105.128 101.075 1.00 26.64  ? 124 THR A C   1 
ATOM   863   O O   . THR A 1 124 ? 129.254 104.393 101.426 1.00 26.64  ? 124 THR A O   1 
ATOM   864   C CB  . THR A 1 124 ? 132.357 103.896 101.102 1.00 26.64  ? 124 THR A CB  1 
ATOM   865   O OG1 . THR A 1 124 ? 133.600 103.745 101.796 1.00 26.64  ? 124 THR A OG1 1 
ATOM   866   C CG2 . THR A 1 124 ? 132.639 104.176 99.635  1.00 26.64  ? 124 THR A CG2 1 
ATOM   867   N N   . GLU A 1 125 ? 130.056 106.034 100.110 1.00 28.64  ? 125 GLU A N   1 
ATOM   868   C CA  . GLU A 1 125 ? 128.826 106.217 99.357  1.00 28.64  ? 125 GLU A CA  1 
ATOM   869   C C   . GLU A 1 125 ? 129.108 106.077 97.867  1.00 28.64  ? 125 GLU A C   1 
ATOM   870   O O   . GLU A 1 125 ? 130.238 106.253 97.408  1.00 28.64  ? 125 GLU A O   1 
ATOM   871   C CB  . GLU A 1 125 ? 128.190 107.577 99.655  1.00 28.64  ? 125 GLU A CB  1 
ATOM   872   C CG  . GLU A 1 125 ? 127.400 107.593 100.946 1.00 28.64  ? 125 GLU A CG  1 
ATOM   873   C CD  . GLU A 1 125 ? 126.801 108.945 101.255 1.00 28.64  ? 125 GLU A CD  1 
ATOM   874   O OE1 . GLU A 1 125 ? 127.442 109.968 100.945 1.00 28.64  ? 125 GLU A OE1 1 
ATOM   875   O OE2 . GLU A 1 125 ? 125.685 108.984 101.810 1.00 28.64  ? 125 GLU A OE2 1 
ATOM   876   N N   . SER A 1 126 ? 128.064 105.740 97.111  1.00 30.06  ? 126 SER A N   1 
ATOM   877   C CA  . SER A 1 126 ? 128.197 105.455 95.683  1.00 30.06  ? 126 SER A CA  1 
ATOM   878   C C   . SER A 1 126 ? 127.842 106.707 94.885  1.00 30.06  ? 126 SER A C   1 
ATOM   879   O O   . SER A 1 126 ? 126.729 106.876 94.391  1.00 30.06  ? 126 SER A O   1 
ATOM   880   C CB  . SER A 1 126 ? 127.327 104.264 95.289  1.00 30.06  ? 126 SER A CB  1 
ATOM   881   O OG  . SER A 1 126 ? 125.958 104.520 95.544  1.00 30.06  ? 126 SER A OG  1 
ATOM   882   N N   . PHE A 1 127 ? 128.820 107.598 94.763  1.00 28.51  ? 127 PHE A N   1 
ATOM   883   C CA  . PHE A 1 127 ? 128.703 108.745 93.878  1.00 28.51  ? 127 PHE A CA  1 
ATOM   884   C C   . PHE A 1 127 ? 128.969 108.325 92.438  1.00 28.51  ? 127 PHE A C   1 
ATOM   885   O O   . PHE A 1 127 ? 129.778 107.433 92.168  1.00 28.51  ? 127 PHE A O   1 
ATOM   886   C CB  . PHE A 1 127 ? 129.687 109.842 94.282  1.00 28.51  ? 127 PHE A CB  1 
ATOM   887   C CG  . PHE A 1 127 ? 129.297 110.586 95.525  1.00 28.51  ? 127 PHE A CG  1 
ATOM   888   C CD1 . PHE A 1 127 ? 128.357 111.598 95.475  1.00 28.51  ? 127 PHE A CD1 1 
ATOM   889   C CD2 . PHE A 1 127 ? 129.883 110.283 96.742  1.00 28.51  ? 127 PHE A CD2 1 
ATOM   890   C CE1 . PHE A 1 127 ? 128.001 112.289 96.616  1.00 28.51  ? 127 PHE A CE1 1 
ATOM   891   C CE2 . PHE A 1 127 ? 129.530 110.970 97.886  1.00 28.51  ? 127 PHE A CE2 1 
ATOM   892   C CZ  . PHE A 1 127 ? 128.588 111.974 97.822  1.00 28.51  ? 127 PHE A CZ  1 
ATOM   893   N N   . THR A 1 128 ? 128.280 108.977 91.506  1.00 30.30  ? 128 THR A N   1 
ATOM   894   C CA  . THR A 1 128 ? 128.472 108.740 90.081  1.00 30.30  ? 128 THR A CA  1 
ATOM   895   C C   . THR A 1 128 ? 128.990 110.016 89.435  1.00 30.30  ? 128 THR A C   1 
ATOM   896   O O   . THR A 1 128 ? 128.344 111.065 89.519  1.00 30.30  ? 128 THR A O   1 
ATOM   897   C CB  . THR A 1 128 ? 127.172 108.292 89.410  1.00 30.30  ? 128 THR A CB  1 
ATOM   898   O OG1 . THR A 1 128 ? 126.588 107.223 90.163  1.00 30.30  ? 128 THR A OG1 1 
ATOM   899   C CG2 . THR A 1 128 ? 127.450 107.808 87.998  1.00 30.30  ? 128 THR A CG2 1 
ATOM   900   N N   . TRP A 1 129 ? 130.147 109.922 88.789  1.00 27.95  ? 129 TRP A N   1 
ATOM   901   C CA  . TRP A 1 129 ? 130.781 111.053 88.117  1.00 27.95  ? 129 TRP A CA  1 
ATOM   902   C C   . TRP A 1 129 ? 130.896 110.698 86.637  1.00 27.95  ? 129 TRP A C   1 
ATOM   903   O O   . TRP A 1 129 ? 131.842 110.021 86.224  1.00 27.95  ? 129 TRP A O   1 
ATOM   904   C CB  . TRP A 1 129 ? 132.141 111.363 88.736  1.00 27.95  ? 129 TRP A CB  1 
ATOM   905   C CG  . TRP A 1 129 ? 132.129 111.421 90.237  1.00 27.95  ? 129 TRP A CG  1 
ATOM   906   C CD1 . TRP A 1 129 ? 132.649 110.498 91.096  1.00 27.95  ? 129 TRP A CD1 1 
ATOM   907   C CD2 . TRP A 1 129 ? 131.575 112.460 91.054  1.00 27.95  ? 129 TRP A CD2 1 
ATOM   908   N NE1 . TRP A 1 129 ? 132.455 110.896 92.394  1.00 27.95  ? 129 TRP A NE1 1 
ATOM   909   C CE2 . TRP A 1 129 ? 131.796 112.096 92.397  1.00 27.95  ? 129 TRP A CE2 1 
ATOM   910   C CE3 . TRP A 1 129 ? 130.912 113.659 90.782  1.00 27.95  ? 129 TRP A CE3 1 
ATOM   911   C CZ2 . TRP A 1 129 ? 131.378 112.889 93.463  1.00 27.95  ? 129 TRP A CZ2 1 
ATOM   912   C CZ3 . TRP A 1 129 ? 130.503 114.445 91.841  1.00 27.95  ? 129 TRP A CZ3 1 
ATOM   913   C CH2 . TRP A 1 129 ? 130.736 114.057 93.165  1.00 27.95  ? 129 TRP A CH2 1 
ATOM   914   N N   . ALA A 1 130 ? 129.936 111.161 85.841  1.00 30.74  ? 130 ALA A N   1 
ATOM   915   C CA  . ALA A 1 130 ? 129.805 110.737 84.453  1.00 30.74  ? 130 ALA A CA  1 
ATOM   916   C C   . ALA A 1 130 ? 130.597 111.650 83.526  1.00 30.74  ? 130 ALA A C   1 
ATOM   917   O O   . ALA A 1 130 ? 130.451 112.875 83.574  1.00 30.74  ? 130 ALA A O   1 
ATOM   918   C CB  . ALA A 1 130 ? 128.334 110.718 84.039  1.00 30.74  ? 130 ALA A CB  1 
ATOM   919   N N   . GLY A 1 131 ? 131.424 111.048 82.676  1.00 31.93  ? 131 GLY A N   1 
ATOM   920   C CA  . GLY A 1 131 ? 132.180 111.783 81.685  1.00 31.93  ? 131 GLY A CA  1 
ATOM   921   C C   . GLY A 1 131 ? 133.534 112.286 82.128  1.00 31.93  ? 131 GLY A C   1 
ATOM   922   O O   . GLY A 1 131 ? 134.145 113.079 81.403  1.00 31.93  ? 131 GLY A O   1 
ATOM   923   N N   . VAL A 1 132 ? 134.025 111.860 83.291  1.00 30.49  ? 132 VAL A N   1 
ATOM   924   C CA  . VAL A 1 132 ? 135.328 112.273 83.790  1.00 30.49  ? 132 VAL A CA  1 
ATOM   925   C C   . VAL A 1 132 ? 136.096 111.036 84.234  1.00 30.49  ? 132 VAL A C   1 
ATOM   926   O O   . VAL A 1 132 ? 135.528 109.963 84.438  1.00 30.49  ? 132 VAL A O   1 
ATOM   927   C CB  . VAL A 1 132 ? 135.220 113.284 84.954  1.00 30.49  ? 132 VAL A CB  1 
ATOM   928   C CG1 . VAL A 1 132 ? 134.640 114.604 84.468  1.00 30.49  ? 132 VAL A CG1 1 
ATOM   929   C CG2 . VAL A 1 132 ? 134.386 112.707 86.083  1.00 30.49  ? 132 VAL A CG2 1 
ATOM   930   N N   . SER A 1 133 ? 137.408 111.198 84.375  1.00 30.81  ? 133 SER A N   1 
ATOM   931   C CA  . SER A 1 133 ? 138.265 110.154 84.914  1.00 30.81  ? 133 SER A CA  1 
ATOM   932   C C   . SER A 1 133 ? 138.492 110.386 86.404  1.00 30.81  ? 133 SER A C   1 
ATOM   933   O O   . SER A 1 133 ? 138.550 111.526 86.870  1.00 30.81  ? 133 SER A O   1 
ATOM   934   C CB  . SER A 1 133 ? 139.604 110.102 84.177  1.00 30.81  ? 133 SER A CB  1 
ATOM   935   O OG  . SER A 1 133 ? 140.225 111.371 84.150  1.00 30.81  ? 133 SER A OG  1 
ATOM   936   N N   . GLN A 1 134 ? 138.611 109.292 87.149  1.00 28.72  ? 134 GLN A N   1 
ATOM   937   C CA  . GLN A 1 134 ? 138.711 109.332 88.600  1.00 28.72  ? 134 GLN A CA  1 
ATOM   938   C C   . GLN A 1 134 ? 140.062 108.800 89.065  1.00 28.72  ? 134 GLN A C   1 
ATOM   939   O O   . GLN A 1 134 ? 140.861 108.284 88.282  1.00 28.72  ? 134 GLN A O   1 
ATOM   940   C CB  . GLN A 1 134 ? 137.578 108.527 89.250  1.00 28.72  ? 134 GLN A CB  1 
ATOM   941   C CG  . GLN A 1 134 ? 136.237 108.667 88.558  1.00 28.72  ? 134 GLN A CG  1 
ATOM   942   C CD  . GLN A 1 134 ? 135.106 108.025 89.337  1.00 28.72  ? 134 GLN A CD  1 
ATOM   943   O OE1 . GLN A 1 134 ? 135.266 107.663 90.501  1.00 28.72  ? 134 GLN A OE1 1 
ATOM   944   N NE2 . GLN A 1 134 ? 133.956 107.877 88.694  1.00 28.72  ? 134 GLN A NE2 1 
ATOM   945   N N   . ASN A 1 135 ? 140.301 108.947 90.371  1.00 28.79  ? 135 ASN A N   1 
ATOM   946   C CA  . ASN A 1 135 ? 141.497 108.430 91.042  1.00 28.79  ? 135 ASN A CA  1 
ATOM   947   C C   . ASN A 1 135 ? 142.781 109.051 90.486  1.00 28.79  ? 135 ASN A C   1 
ATOM   948   O O   . ASN A 1 135 ? 143.723 108.353 90.109  1.00 28.79  ? 135 ASN A O   1 
ATOM   949   C CB  . ASN A 1 135 ? 141.553 106.900 90.965  1.00 28.79  ? 135 ASN A CB  1 
ATOM   950   C CG  . ASN A 1 135 ? 140.242 106.250 91.354  1.00 28.79  ? 135 ASN A CG  1 
ATOM   951   O OD1 . ASN A 1 135 ? 139.700 106.509 92.427  1.00 28.79  ? 135 ASN A OD1 1 
ATOM   952   N ND2 . ASN A 1 135 ? 139.724 105.400 90.481  1.00 28.79  ? 135 ASN A ND2 1 
ATOM   953   N N   . GLY A 1 136 ? 142.815 110.380 90.442  1.00 29.02  ? 136 GLY A N   1 
ATOM   954   C CA  . GLY A 1 136 ? 144.044 111.068 90.100  1.00 29.02  ? 136 GLY A CA  1 
ATOM   955   C C   . GLY A 1 136 ? 145.061 110.997 91.225  1.00 29.02  ? 136 GLY A C   1 
ATOM   956   O O   . GLY A 1 136 ? 144.717 110.955 92.405  1.00 29.02  ? 136 GLY A O   1 
ATOM   957   N N   . GLY A 1 137 ? 146.342 110.993 90.848  1.00 31.31  ? 137 GLY A N   1 
ATOM   958   C CA  . GLY A 1 137 ? 147.419 110.813 91.800  1.00 31.31  ? 137 GLY A CA  1 
ATOM   959   C C   . GLY A 1 137 ? 148.562 111.779 91.555  1.00 31.31  ? 137 GLY A C   1 
ATOM   960   O O   . GLY A 1 137 ? 148.521 112.600 90.639  1.00 31.31  ? 137 GLY A O   1 
ATOM   961   N N   . SER A 1 138 ? 149.588 111.659 92.395  1.00 32.05  ? 138 SER A N   1 
ATOM   962   C CA  . SER A 1 138 ? 150.721 112.571 92.356  1.00 32.05  ? 138 SER A CA  1 
ATOM   963   C C   . SER A 1 138 ? 151.961 111.877 92.901  1.00 32.05  ? 138 SER A C   1 
ATOM   964   O O   . SER A 1 138 ? 151.868 110.971 93.732  1.00 32.05  ? 138 SER A O   1 
ATOM   965   C CB  . SER A 1 138 ? 150.436 113.844 93.161  1.00 32.05  ? 138 SER A CB  1 
ATOM   966   O OG  . SER A 1 138 ? 151.494 114.774 93.046  1.00 32.05  ? 138 SER A OG  1 
ATOM   967   N N   . SER A 1 139 ? 153.127 112.317 92.427  1.00 32.51  ? 139 SER A N   1 
ATOM   968   C CA  . SER A 1 139 ? 154.389 111.831 92.970  1.00 32.51  ? 139 SER A CA  1 
ATOM   969   C C   . SER A 1 139 ? 154.700 112.420 94.340  1.00 32.51  ? 139 SER A C   1 
ATOM   970   O O   . SER A 1 139 ? 155.570 111.891 95.038  1.00 32.51  ? 139 SER A O   1 
ATOM   971   C CB  . SER A 1 139 ? 155.531 112.133 92.001  1.00 32.51  ? 139 SER A CB  1 
ATOM   972   O OG  . SER A 1 139 ? 155.737 113.527 91.868  1.00 32.51  ? 139 SER A OG  1 
ATOM   973   N N   . ALA A 1 140 ? 154.013 113.489 94.741  1.00 30.34  ? 140 ALA A N   1 
ATOM   974   C CA  . ALA A 1 140 ? 154.181 114.049 96.073  1.00 30.34  ? 140 ALA A CA  1 
ATOM   975   C C   . ALA A 1 140 ? 153.509 113.217 97.156  1.00 30.34  ? 140 ALA A C   1 
ATOM   976   O O   . ALA A 1 140 ? 153.730 113.480 98.342  1.00 30.34  ? 140 ALA A O   1 
ATOM   977   C CB  . ALA A 1 140 ? 153.636 115.478 96.117  1.00 30.34  ? 140 ALA A CB  1 
ATOM   978   N N   . CYS A 1 141 ? 152.695 112.231 96.782  1.00 32.50  ? 141 CYS A N   1 
ATOM   979   C CA  . CYS A 1 141 ? 151.954 111.400 97.733  1.00 32.50  ? 141 CYS A CA  1 
ATOM   980   C C   . CYS A 1 141 ? 152.047 109.961 97.229  1.00 32.50  ? 141 CYS A C   1 
ATOM   981   O O   . CYS A 1 141 ? 151.173 109.495 96.498  1.00 32.50  ? 141 CYS A O   1 
ATOM   982   C CB  . CYS A 1 141 ? 150.510 111.876 97.847  1.00 32.50  ? 141 CYS A CB  1 
ATOM   983   S SG  . CYS A 1 141 ? 149.600 111.301 99.294  1.00 32.50  ? 141 CYS A SG  1 
ATOM   984   N N   . LYS A 1 142 ? 153.093 109.254 97.643  1.00 36.29  ? 142 LYS A N   1 
ATOM   985   C CA  . LYS A 1 142 ? 153.388 107.923 97.130  1.00 36.29  ? 142 LYS A CA  1 
ATOM   986   C C   . LYS A 1 142 ? 152.813 106.858 98.053  1.00 36.29  ? 142 LYS A C   1 
ATOM   987   O O   . LYS A 1 142 ? 153.000 106.919 99.272  1.00 36.29  ? 142 LYS A O   1 
ATOM   988   C CB  . LYS A 1 142 ? 154.895 107.717 96.975  1.00 36.29  ? 142 LYS A CB  1 
ATOM   989   C CG  . LYS A 1 142 ? 155.596 108.813 96.204  1.00 36.29  ? 142 LYS A CG  1 
ATOM   990   C CD  . LYS A 1 142 ? 156.520 108.236 95.151  1.00 36.29  ? 142 LYS A CD  1 
ATOM   991   C CE  . LYS A 1 142 ? 155.746 107.821 93.916  1.00 36.29  ? 142 LYS A CE  1 
ATOM   992   N NZ  . LYS A 1 142 ? 156.556 107.950 92.674  1.00 36.29  ? 142 LYS A NZ  1 
ATOM   993   N N   . ARG A 1 143 ? 152.118 105.889 97.469  1.00 35.99  ? 143 ARG A N   1 
ATOM   994   C CA  . ARG A 1 143 ? 151.645 104.699 98.171  1.00 35.99  ? 143 ARG A CA  1 
ATOM   995   C C   . ARG A 1 143 ? 152.466 103.529 97.635  1.00 35.99  ? 143 ARG A C   1 
ATOM   996   O O   . ARG A 1 143 ? 152.065 102.850 96.690  1.00 35.99  ? 143 ARG A O   1 
ATOM   997   C CB  . ARG A 1 143 ? 150.149 104.479 97.970  1.00 35.99  ? 143 ARG A CB  1 
ATOM   998   C CG  . ARG A 1 143 ? 149.293 105.703 98.237  1.00 35.99  ? 143 ARG A CG  1 
ATOM   999   C CD  . ARG A 1 143 ? 147.810 105.367 98.191  1.00 35.99  ? 143 ARG A CD  1 
ATOM   1000  N NE  . ARG A 1 143 ? 147.039 106.189 99.114  1.00 35.99  ? 143 ARG A NE  1 
ATOM   1001  C CZ  . ARG A 1 143 ? 146.840 105.899 100.392 1.00 35.99  ? 143 ARG A CZ  1 
ATOM   1002  N NH1 . ARG A 1 143 ? 147.311 104.787 100.930 1.00 35.99  ? 143 ARG A NH1 1 
ATOM   1003  N NH2 . ARG A 1 143 ? 146.152 106.747 101.150 1.00 35.99  ? 143 ARG A NH2 1 
ATOM   1004  N N   . GLY A 1 144 ? 153.625 103.305 98.245  1.00 40.89  ? 144 GLY A N   1 
ATOM   1005  C CA  . GLY A 1 144 ? 154.558 102.317 97.762  1.00 40.89  ? 144 GLY A CA  1 
ATOM   1006  C C   . GLY A 1 144 ? 155.384 102.852 96.611  1.00 40.89  ? 144 GLY A C   1 
ATOM   1007  O O   . GLY A 1 144 ? 156.051 103.885 96.722  1.00 40.89  ? 144 GLY A O   1 
ATOM   1008  N N   . PRO A 1 145 ? 155.362 102.151 95.479  1.00 42.61  ? 145 PRO A N   1 
ATOM   1009  C CA  . PRO A 1 145 ? 156.087 102.638 94.298  1.00 42.61  ? 145 PRO A CA  1 
ATOM   1010  C C   . PRO A 1 145 ? 155.255 103.556 93.412  1.00 42.61  ? 145 PRO A C   1 
ATOM   1011  O O   . PRO A 1 145 ? 155.807 104.356 92.650  1.00 42.61  ? 145 PRO A O   1 
ATOM   1012  C CB  . PRO A 1 145 ? 156.462 101.345 93.562  1.00 42.61  ? 145 PRO A CB  1 
ATOM   1013  C CG  . PRO A 1 145 ? 155.490 100.300 94.057  1.00 42.61  ? 145 PRO A CG  1 
ATOM   1014  C CD  . PRO A 1 145 ? 154.748 100.832 95.253  1.00 42.61  ? 145 PRO A CD  1 
ATOM   1015  N N   . ALA A 1 146 ? 153.934 103.455 93.503  1.00 38.84  ? 146 ALA A N   1 
ATOM   1016  C CA  . ALA A 1 146 ? 153.042 104.167 92.602  1.00 38.84  ? 146 ALA A CA  1 
ATOM   1017  C C   . ALA A 1 146 ? 152.664 105.537 93.156  1.00 38.84  ? 146 ALA A C   1 
ATOM   1018  O O   . ALA A 1 146 ? 152.765 105.803 94.355  1.00 38.84  ? 146 ALA A O   1 
ATOM   1019  C CB  . ALA A 1 146 ? 151.780 103.347 92.343  1.00 38.84  ? 146 ALA A CB  1 
ATOM   1020  N N   . ASN A 1 147 ? 152.230 106.413 92.252  1.00 34.87  ? 147 ASN A N   1 
ATOM   1021  C CA  . ASN A 1 147 ? 151.670 107.696 92.651  1.00 34.87  ? 147 ASN A CA  1 
ATOM   1022  C C   . ASN A 1 147 ? 150.310 107.490 93.306  1.00 34.87  ? 147 ASN A C   1 
ATOM   1023  O O   . ASN A 1 147 ? 149.523 106.642 92.880  1.00 34.87  ? 147 ASN A O   1 
ATOM   1024  C CB  . ASN A 1 147 ? 151.534 108.618 91.439  1.00 34.87  ? 147 ASN A CB  1 
ATOM   1025  C CG  . ASN A 1 147 ? 152.874 109.075 90.895  1.00 34.87  ? 147 ASN A CG  1 
ATOM   1026  O OD1 . ASN A 1 147 ? 153.923 108.753 91.447  1.00 34.87  ? 147 ASN A OD1 1 
ATOM   1027  N ND2 . ASN A 1 147 ? 152.844 109.827 89.805  1.00 34.87  ? 147 ASN A ND2 1 
ATOM   1028  N N   . GLY A 1 148 ? 150.035 108.268 94.348  1.00 30.56  ? 148 GLY A N   1 
ATOM   1029  C CA  . GLY A 1 148 ? 148.783 108.129 95.066  1.00 30.56  ? 148 GLY A CA  1 
ATOM   1030  C C   . GLY A 1 148 ? 148.151 109.444 95.471  1.00 30.56  ? 148 GLY A C   1 
ATOM   1031  O O   . GLY A 1 148 ? 148.491 110.500 94.931  1.00 30.56  ? 148 GLY A O   1 
ATOM   1032  N N   . PHE A 1 149 ? 147.235 109.388 96.431  1.00 25.38  ? 149 PHE A N   1 
ATOM   1033  C CA  . PHE A 1 149 ? 146.466 110.551 96.854  1.00 25.38  ? 149 PHE A CA  1 
ATOM   1034  C C   . PHE A 1 149 ? 145.880 110.255 98.229  1.00 25.38  ? 149 PHE A C   1 
ATOM   1035  O O   . PHE A 1 149 ? 146.033 109.153 98.762  1.00 25.38  ? 149 PHE A O   1 
ATOM   1036  C CB  . PHE A 1 149 ? 145.377 110.882 95.829  1.00 25.38  ? 149 PHE A CB  1 
ATOM   1037  C CG  . PHE A 1 149 ? 144.864 112.286 95.913  1.00 25.38  ? 149 PHE A CG  1 
ATOM   1038  C CD1 . PHE A 1 149 ? 145.724 113.364 95.803  1.00 25.38  ? 149 PHE A CD1 1 
ATOM   1039  C CD2 . PHE A 1 149 ? 143.514 112.530 96.087  1.00 25.38  ? 149 PHE A CD2 1 
ATOM   1040  C CE1 . PHE A 1 149 ? 145.247 114.657 95.875  1.00 25.38  ? 149 PHE A CE1 1 
ATOM   1041  C CE2 . PHE A 1 149 ? 143.033 113.818 96.159  1.00 25.38  ? 149 PHE A CE2 1 
ATOM   1042  C CZ  . PHE A 1 149 ? 143.900 114.883 96.051  1.00 25.38  ? 149 PHE A CZ  1 
ATOM   1043  N N   . PHE A 1 150 ? 145.212 111.254 98.803  1.00 24.52  ? 150 PHE A N   1 
ATOM   1044  C CA  . PHE A 1 150 ? 144.471 111.049 100.041 1.00 24.52  ? 150 PHE A CA  1 
ATOM   1045  C C   . PHE A 1 150 ? 143.430 109.953 99.854  1.00 24.52  ? 150 PHE A C   1 
ATOM   1046  O O   . PHE A 1 150 ? 142.764 109.877 98.819  1.00 24.52  ? 150 PHE A O   1 
ATOM   1047  C CB  . PHE A 1 150 ? 143.789 112.346 100.477 1.00 24.52  ? 150 PHE A CB  1 
ATOM   1048  C CG  . PHE A 1 150 ? 144.739 113.477 100.740 1.00 24.52  ? 150 PHE A CG  1 
ATOM   1049  C CD1 . PHE A 1 150 ? 145.414 113.567 101.944 1.00 24.52  ? 150 PHE A CD1 1 
ATOM   1050  C CD2 . PHE A 1 150 ? 144.951 114.458 99.785  1.00 24.52  ? 150 PHE A CD2 1 
ATOM   1051  C CE1 . PHE A 1 150 ? 146.285 114.608 102.189 1.00 24.52  ? 150 PHE A CE1 1 
ATOM   1052  C CE2 . PHE A 1 150 ? 145.822 115.503 100.025 1.00 24.52  ? 150 PHE A CE2 1 
ATOM   1053  C CZ  . PHE A 1 150 ? 146.489 115.578 101.227 1.00 24.52  ? 150 PHE A CZ  1 
ATOM   1054  N N   . SER A 1 151 ? 143.288 109.096 100.867 1.00 25.34  ? 151 SER A N   1 
ATOM   1055  C CA  . SER A 1 151 ? 142.431 107.924 100.725 1.00 25.34  ? 151 SER A CA  1 
ATOM   1056  C C   . SER A 1 151 ? 140.944 108.262 100.764 1.00 25.34  ? 151 SER A C   1 
ATOM   1057  O O   . SER A 1 151 ? 140.139 107.490 100.238 1.00 25.34  ? 151 SER A O   1 
ATOM   1058  C CB  . SER A 1 151 ? 142.763 106.894 101.807 1.00 25.34  ? 151 SER A CB  1 
ATOM   1059  O OG  . SER A 1 151 ? 142.245 107.277 103.067 1.00 25.34  ? 151 SER A OG  1 
ATOM   1060  N N   . ARG A 1 152 ? 140.557 109.389 101.360 1.00 24.41  ? 152 ARG A N   1 
ATOM   1061  C CA  . ARG A 1 152 ? 139.153 109.753 101.491 1.00 24.41  ? 152 ARG A CA  1 
ATOM   1062  C C   . ARG A 1 152 ? 138.689 110.753 100.435 1.00 24.41  ? 152 ARG A C   1 
ATOM   1063  O O   . ARG A 1 152 ? 137.548 111.218 100.500 1.00 24.41  ? 152 ARG A O   1 
ATOM   1064  C CB  . ARG A 1 152 ? 138.879 110.314 102.890 1.00 24.41  ? 152 ARG A CB  1 
ATOM   1065  C CG  . ARG A 1 152 ? 139.263 109.385 104.033 1.00 24.41  ? 152 ARG A CG  1 
ATOM   1066  C CD  . ARG A 1 152 ? 138.550 108.047 103.942 1.00 24.41  ? 152 ARG A CD  1 
ATOM   1067  N NE  . ARG A 1 152 ? 138.606 107.313 105.199 1.00 24.41  ? 152 ARG A NE  1 
ATOM   1068  C CZ  . ARG A 1 152 ? 138.491 105.996 105.305 1.00 24.41  ? 152 ARG A CZ  1 
ATOM   1069  N NH1 . ARG A 1 152 ? 138.315 105.230 104.243 1.00 24.41  ? 152 ARG A NH1 1 
ATOM   1070  N NH2 . ARG A 1 152 ? 138.550 105.434 106.509 1.00 24.41  ? 152 ARG A NH2 1 
ATOM   1071  N N   . LEU A 1 153 ? 139.537 111.094 99.468  1.00 23.32  ? 153 LEU A N   1 
ATOM   1072  C CA  . LEU A 1 153 ? 139.201 112.076 98.447  1.00 23.32  ? 153 LEU A CA  1 
ATOM   1073  C C   . LEU A 1 153 ? 139.435 111.481 97.065  1.00 23.32  ? 153 LEU A C   1 
ATOM   1074  O O   . LEU A 1 153 ? 140.250 110.572 96.896  1.00 23.32  ? 153 LEU A O   1 
ATOM   1075  C CB  . LEU A 1 153 ? 140.021 113.363 98.618  1.00 23.32  ? 153 LEU A CB  1 
ATOM   1076  C CG  . LEU A 1 153 ? 139.852 114.108 99.947  1.00 23.32  ? 153 LEU A CG  1 
ATOM   1077  C CD1 . LEU A 1 153 ? 140.947 115.148 100.134 1.00 23.32  ? 153 LEU A CD1 1 
ATOM   1078  C CD2 . LEU A 1 153 ? 138.480 114.751 100.046 1.00 23.32  ? 153 LEU A CD2 1 
ATOM   1079  N N   . ASN A 1 154 ? 138.711 112.007 96.077  1.00 23.90  ? 154 ASN A N   1 
ATOM   1080  C CA  . ASN A 1 154 ? 138.742 111.500 94.707  1.00 23.90  ? 154 ASN A CA  1 
ATOM   1081  C C   . ASN A 1 154 ? 139.057 112.658 93.766  1.00 23.90  ? 154 ASN A C   1 
ATOM   1082  O O   . ASN A 1 154 ? 138.268 113.599 93.649  1.00 23.90  ? 154 ASN A O   1 
ATOM   1083  C CB  . ASN A 1 154 ? 137.408 110.839 94.349  1.00 23.90  ? 154 ASN A CB  1 
ATOM   1084  C CG  . ASN A 1 154 ? 137.471 110.035 93.066  1.00 23.90  ? 154 ASN A CG  1 
ATOM   1085  O OD1 . ASN A 1 154 ? 138.519 109.922 92.436  1.00 23.90  ? 154 ASN A OD1 1 
ATOM   1086  N ND2 . ASN A 1 154 ? 136.339 109.471 92.673  1.00 23.90  ? 154 ASN A ND2 1 
ATOM   1087  N N   . TRP A 1 155 ? 140.209 112.592 93.104  1.00 26.77  ? 155 TRP A N   1 
ATOM   1088  C CA  . TRP A 1 155 ? 140.666 113.652 92.211  1.00 26.77  ? 155 TRP A CA  1 
ATOM   1089  C C   . TRP A 1 155 ? 140.146 113.387 90.800  1.00 26.77  ? 155 TRP A C   1 
ATOM   1090  O O   . TRP A 1 155 ? 140.517 112.391 90.174  1.00 26.77  ? 155 TRP A O   1 
ATOM   1091  C CB  . TRP A 1 155 ? 142.193 113.734 92.225  1.00 26.77  ? 155 TRP A CB  1 
ATOM   1092  C CG  . TRP A 1 155 ? 142.770 114.974 91.603  1.00 26.77  ? 155 TRP A CG  1 
ATOM   1093  C CD1 . TRP A 1 155 ? 142.108 115.906 90.860  1.00 26.77  ? 155 TRP A CD1 1 
ATOM   1094  C CD2 . TRP A 1 155 ? 144.132 115.412 91.673  1.00 26.77  ? 155 TRP A CD2 1 
ATOM   1095  N NE1 . TRP A 1 155 ? 142.970 116.896 90.464  1.00 26.77  ? 155 TRP A NE1 1 
ATOM   1096  C CE2 . TRP A 1 155 ? 144.219 116.617 90.950  1.00 26.77  ? 155 TRP A CE2 1 
ATOM   1097  C CE3 . TRP A 1 155 ? 145.286 114.902 92.276  1.00 26.77  ? 155 TRP A CE3 1 
ATOM   1098  C CZ2 . TRP A 1 155 ? 145.414 117.321 90.815  1.00 26.77  ? 155 TRP A CZ2 1 
ATOM   1099  C CZ3 . TRP A 1 155 ? 146.469 115.602 92.140  1.00 26.77  ? 155 TRP A CZ3 1 
ATOM   1100  C CH2 . TRP A 1 155 ? 146.524 116.798 91.416  1.00 26.77  ? 155 TRP A CH2 1 
ATOM   1101  N N   . LEU A 1 156 ? 139.299 114.284 90.301  1.00 27.46  ? 156 LEU A N   1 
ATOM   1102  C CA  . LEU A 1 156 ? 138.656 114.131 89.001  1.00 27.46  ? 156 LEU A CA  1 
ATOM   1103  C C   . LEU A 1 156 ? 139.338 115.020 87.969  1.00 27.46  ? 156 LEU A C   1 
ATOM   1104  O O   . LEU A 1 156 ? 139.620 116.191 88.243  1.00 27.46  ? 156 LEU A O   1 
ATOM   1105  C CB  . LEU A 1 156 ? 137.168 114.482 89.084  1.00 27.46  ? 156 LEU A CB  1 
ATOM   1106  C CG  . LEU A 1 156 ? 136.299 113.830 90.165  1.00 27.46  ? 156 LEU A CG  1 
ATOM   1107  C CD1 . LEU A 1 156 ? 134.894 114.407 90.131  1.00 27.46  ? 156 LEU A CD1 1 
ATOM   1108  C CD2 . LEU A 1 156 ? 136.260 112.316 90.021  1.00 27.46  ? 156 LEU A CD2 1 
ATOM   1109  N N   . THR A 1 157 ? 139.599 114.465 86.785  1.00 30.08  ? 157 THR A N   1 
ATOM   1110  C CA  . THR A 1 157 ? 140.151 115.209 85.658  1.00 30.08  ? 157 THR A CA  1 
ATOM   1111  C C   . THR A 1 157 ? 139.363 114.867 84.397  1.00 30.08  ? 157 THR A C   1 
ATOM   1112  O O   . THR A 1 157 ? 138.430 114.061 84.419  1.00 30.08  ? 157 THR A O   1 
ATOM   1113  C CB  . THR A 1 157 ? 141.649 114.923 85.456  1.00 30.08  ? 157 THR A CB  1 
ATOM   1114  O OG1 . THR A 1 157 ? 141.859 113.517 85.273  1.00 30.08  ? 157 THR A OG1 1 
ATOM   1115  C CG2 . THR A 1 157 ? 142.468 115.416 86.645  1.00 30.08  ? 157 THR A CG2 1 
ATOM   1116  N N   . LYS A 1 158 ? 139.749 115.490 83.286  1.00 32.79  ? 158 LYS A N   1 
ATOM   1117  C CA  . LYS A 1 158 ? 139.031 115.325 82.031  1.00 32.79  ? 158 LYS A CA  1 
ATOM   1118  C C   . LYS A 1 158 ? 139.130 113.892 81.515  1.00 32.79  ? 158 LYS A C   1 
ATOM   1119  O O   . LYS A 1 158 ? 140.093 113.171 81.786  1.00 32.79  ? 158 LYS A O   1 
ATOM   1120  C CB  . LYS A 1 158 ? 139.573 116.291 80.975  1.00 32.79  ? 158 LYS A CB  1 
ATOM   1121  C CG  . LYS A 1 158 ? 140.887 115.848 80.359  1.00 32.79  ? 158 LYS A CG  1 
ATOM   1122  C CD  . LYS A 1 158 ? 141.308 116.735 79.206  1.00 32.79  ? 158 LYS A CD  1 
ATOM   1123  C CE  . LYS A 1 158 ? 142.704 116.368 78.730  1.00 32.79  ? 158 LYS A CE  1 
ATOM   1124  N NZ  . LYS A 1 158 ? 143.219 117.308 77.704  1.00 32.79  ? 158 LYS A NZ  1 
ATOM   1125  N N   . SER A 1 159 ? 138.106 113.480 80.773  1.00 35.55  ? 159 SER A N   1 
ATOM   1126  C CA  . SER A 1 159 ? 138.076 112.185 80.105  1.00 35.55  ? 159 SER A CA  1 
ATOM   1127  C C   . SER A 1 159 ? 138.062 112.425 78.604  1.00 35.55  ? 159 SER A C   1 
ATOM   1128  O O   . SER A 1 159 ? 137.134 113.050 78.082  1.00 35.55  ? 159 SER A O   1 
ATOM   1129  C CB  . SER A 1 159 ? 136.858 111.366 80.533  1.00 35.55  ? 159 SER A CB  1 
ATOM   1130  O OG  . SER A 1 159 ? 136.853 110.094 79.912  1.00 35.55  ? 159 SER A OG  1 
ATOM   1131  N N   . GLY A 1 160 ? 139.085 111.931 77.914  1.00 38.15  ? 160 GLY A N   1 
ATOM   1132  C CA  . GLY A 1 160 ? 139.220 112.200 76.499  1.00 38.15  ? 160 GLY A CA  1 
ATOM   1133  C C   . GLY A 1 160 ? 139.611 113.638 76.238  1.00 38.15  ? 160 GLY A C   1 
ATOM   1134  O O   . GLY A 1 160 ? 140.748 114.036 76.505  1.00 38.15  ? 160 GLY A O   1 
ATOM   1135  N N   . SER A 1 161 ? 138.675 114.435 75.720  1.00 38.10  ? 161 SER A N   1 
ATOM   1136  C CA  . SER A 1 161 ? 138.924 115.848 75.466  1.00 38.10  ? 161 SER A CA  1 
ATOM   1137  C C   . SER A 1 161 ? 137.830 116.740 76.042  1.00 38.10  ? 161 SER A C   1 
ATOM   1138  O O   . SER A 1 161 ? 137.700 117.894 75.625  1.00 38.10  ? 161 SER A O   1 
ATOM   1139  C CB  . SER A 1 161 ? 139.077 116.106 73.965  1.00 38.10  ? 161 SER A CB  1 
ATOM   1140  O OG  . SER A 1 161 ? 137.821 116.363 73.362  1.00 38.10  ? 161 SER A OG  1 
ATOM   1141  N N   . SER A 1 162 ? 137.043 116.241 76.993  1.00 35.55  ? 162 SER A N   1 
ATOM   1142  C CA  . SER A 1 162 ? 135.932 117.008 77.534  1.00 35.55  ? 162 SER A CA  1 
ATOM   1143  C C   . SER A 1 162 ? 135.853 116.838 79.044  1.00 35.55  ? 162 SER A C   1 
ATOM   1144  O O   . SER A 1 162 ? 136.273 115.820 79.598  1.00 35.55  ? 162 SER A O   1 
ATOM   1145  C CB  . SER A 1 162 ? 134.601 116.591 76.895  1.00 35.55  ? 162 SER A CB  1 
ATOM   1146  O OG  . SER A 1 162 ? 134.300 115.239 77.182  1.00 35.55  ? 162 SER A OG  1 
ATOM   1147  N N   . TYR A 1 163 ? 135.303 117.857 79.700  1.00 30.82  ? 163 TYR A N   1 
ATOM   1148  C CA  . TYR A 1 163 ? 135.008 117.832 81.132  1.00 30.82  ? 163 TYR A CA  1 
ATOM   1149  C C   . TYR A 1 163 ? 133.602 118.393 81.295  1.00 30.82  ? 163 TYR A C   1 
ATOM   1150  O O   . TYR A 1 163 ? 133.427 119.621 81.373  1.00 30.82  ? 163 TYR A O   1 
ATOM   1151  C CB  . TYR A 1 163 ? 136.028 118.641 81.927  1.00 30.82  ? 163 TYR A CB  1 
ATOM   1152  C CG  . TYR A 1 163 ? 135.940 118.504 83.438  1.00 30.82  ? 163 TYR A CG  1 
ATOM   1153  C CD1 . TYR A 1 163 ? 134.881 119.051 84.150  1.00 30.82  ? 163 TYR A CD1 1 
ATOM   1154  C CD2 . TYR A 1 163 ? 136.929 117.843 84.151  1.00 30.82  ? 163 TYR A CD2 1 
ATOM   1155  C CE1 . TYR A 1 163 ? 134.803 118.934 85.524  1.00 30.82  ? 163 TYR A CE1 1 
ATOM   1156  C CE2 . TYR A 1 163 ? 136.863 117.723 85.525  1.00 30.82  ? 163 TYR A CE2 1 
ATOM   1157  C CZ  . TYR A 1 163 ? 135.798 118.270 86.207  1.00 30.82  ? 163 TYR A CZ  1 
ATOM   1158  O OH  . TYR A 1 163 ? 135.727 118.152 87.573  1.00 30.82  ? 163 TYR A OH  1 
ATOM   1159  N N   . PRO A 1 164 ? 132.582 117.541 81.345  1.00 32.48  ? 164 PRO A N   1 
ATOM   1160  C CA  . PRO A 1 164 ? 131.202 118.035 81.359  1.00 32.48  ? 164 PRO A CA  1 
ATOM   1161  C C   . PRO A 1 164 ? 130.843 118.649 82.703  1.00 32.48  ? 164 PRO A C   1 
ATOM   1162  O O   . PRO A 1 164 ? 131.576 118.552 83.689  1.00 32.48  ? 164 PRO A O   1 
ATOM   1163  C CB  . PRO A 1 164 ? 130.365 116.780 81.079  1.00 32.48  ? 164 PRO A CB  1 
ATOM   1164  C CG  . PRO A 1 164 ? 131.360 115.669 80.816  1.00 32.48  ? 164 PRO A CG  1 
ATOM   1165  C CD  . PRO A 1 164 ? 132.631 116.079 81.467  1.00 32.48  ? 164 PRO A CD  1 
ATOM   1166  N N   . LEU A 1 165 ? 129.682 119.295 82.729  1.00 31.06  ? 165 LEU A N   1 
ATOM   1167  C CA  . LEU A 1 165 ? 129.174 119.887 83.958  1.00 31.06  ? 165 LEU A CA  1 
ATOM   1168  C C   . LEU A 1 165 ? 128.657 118.791 84.883  1.00 31.06  ? 165 LEU A C   1 
ATOM   1169  O O   . LEU A 1 165 ? 127.768 118.021 84.508  1.00 31.06  ? 165 LEU A O   1 
ATOM   1170  C CB  . LEU A 1 165 ? 128.069 120.890 83.640  1.00 31.06  ? 165 LEU A CB  1 
ATOM   1171  C CG  . LEU A 1 165 ? 127.284 121.472 84.817  1.00 31.06  ? 165 LEU A CG  1 
ATOM   1172  C CD1 . LEU A 1 165 ? 128.149 122.400 85.650  1.00 31.06  ? 165 LEU A CD1 1 
ATOM   1173  C CD2 . LEU A 1 165 ? 126.044 122.192 84.322  1.00 31.06  ? 165 LEU A CD2 1 
ATOM   1174  N N   . LEU A 1 166 ? 129.210 118.721 86.090  1.00 29.87  ? 166 LEU A N   1 
ATOM   1175  C CA  . LEU A 1 166 ? 128.829 117.702 87.057  1.00 29.87  ? 166 LEU A CA  1 
ATOM   1176  C C   . LEU A 1 166 ? 127.700 118.223 87.936  1.00 29.87  ? 166 LEU A C   1 
ATOM   1177  O O   . LEU A 1 166 ? 127.769 119.348 88.437  1.00 29.87  ? 166 LEU A O   1 
ATOM   1178  C CB  . LEU A 1 166 ? 130.028 117.296 87.914  1.00 29.87  ? 166 LEU A CB  1 
ATOM   1179  C CG  . LEU A 1 166 ? 131.220 116.689 87.172  1.00 29.87  ? 166 LEU A CG  1 
ATOM   1180  C CD1 . LEU A 1 166 ? 132.460 116.697 88.049  1.00 29.87  ? 166 LEU A CD1 1 
ATOM   1181  C CD2 . LEU A 1 166 ? 130.900 115.282 86.700  1.00 29.87  ? 166 LEU A CD2 1 
ATOM   1182  N N   . ASN A 1 167 ? 126.674 117.391 88.130  1.00 30.19  ? 167 ASN A N   1 
ATOM   1183  C CA  . ASN A 1 167 ? 125.483 117.768 88.894  1.00 30.19  ? 167 ASN A CA  1 
ATOM   1184  C C   . ASN A 1 167 ? 124.983 116.509 89.600  1.00 30.19  ? 167 ASN A C   1 
ATOM   1185  O O   . ASN A 1 167 ? 124.265 115.708 88.998  1.00 30.19  ? 167 ASN A O   1 
ATOM   1186  C CB  . ASN A 1 167 ? 124.416 118.361 87.979  1.00 30.19  ? 167 ASN A CB  1 
ATOM   1187  C CG  . ASN A 1 167 ? 123.268 119.000 88.743  1.00 30.19  ? 167 ASN A CG  1 
ATOM   1188  O OD1 . ASN A 1 167 ? 123.477 119.846 89.608  1.00 30.19  ? 167 ASN A OD1 1 
ATOM   1189  N ND2 . ASN A 1 167 ? 122.042 118.590 88.419  1.00 30.19  ? 167 ASN A ND2 1 
ATOM   1190  N N   . VAL A 1 168 ? 125.363 116.338 90.868  1.00 27.99  ? 168 VAL A N   1 
ATOM   1191  C CA  . VAL A 1 168 ? 125.013 115.131 91.607  1.00 27.99  ? 168 VAL A CA  1 
ATOM   1192  C C   . VAL A 1 168 ? 124.337 115.504 92.919  1.00 27.99  ? 168 VAL A C   1 
ATOM   1193  O O   . VAL A 1 168 ? 124.532 116.592 93.465  1.00 27.99  ? 168 VAL A O   1 
ATOM   1194  C CB  . VAL A 1 168 ? 126.232 114.218 91.876  1.00 27.99  ? 168 VAL A CB  1 
ATOM   1195  C CG1 . VAL A 1 168 ? 126.986 113.929 90.590  1.00 27.99  ? 168 VAL A CG1 1 
ATOM   1196  C CG2 . VAL A 1 168 ? 127.148 114.841 92.913  1.00 27.99  ? 168 VAL A CG2 1 
ATOM   1197  N N   . THR A 1 169 ? 123.534 114.570 93.422  1.00 30.23  ? 169 THR A N   1 
ATOM   1198  C CA  . THR A 1 169 ? 122.746 114.779 94.626  1.00 30.23  ? 169 THR A CA  1 
ATOM   1199  C C   . THR A 1 169 ? 122.810 113.538 95.506  1.00 30.23  ? 169 THR A C   1 
ATOM   1200  O O   . THR A 1 169 ? 122.999 112.420 95.022  1.00 30.23  ? 169 THR A O   1 
ATOM   1201  C CB  . THR A 1 169 ? 121.286 115.116 94.285  1.00 30.23  ? 169 THR A CB  1 
ATOM   1202  O OG1 . THR A 1 169 ? 120.524 115.243 95.489  1.00 30.23  ? 169 THR A OG1 1 
ATOM   1203  C CG2 . THR A 1 169 ? 120.678 114.036 93.417  1.00 30.23  ? 169 THR A CG2 1 
ATOM   1204  N N   . MET A 1 170 ? 122.657 113.753 96.808  1.00 31.01  ? 170 MET A N   1 
ATOM   1205  C CA  . MET A 1 170 ? 122.685 112.673 97.787  1.00 31.01  ? 170 MET A CA  1 
ATOM   1206  C C   . MET A 1 170 ? 121.829 113.045 98.992  1.00 31.01  ? 170 MET A C   1 
ATOM   1207  O O   . MET A 1 170 ? 122.131 114.020 99.692  1.00 31.01  ? 170 MET A O   1 
ATOM   1208  C CB  . MET A 1 170 ? 124.123 112.367 98.210  1.00 31.01  ? 170 MET A CB  1 
ATOM   1209  C CG  . MET A 1 170 ? 124.261 111.219 99.199  1.00 31.01  ? 170 MET A CG  1 
ATOM   1210  S SD  . MET A 1 170 ? 124.069 109.589 98.451  1.00 31.01  ? 170 MET A SD  1 
ATOM   1211  C CE  . MET A 1 170 ? 125.278 109.652 97.135  1.00 31.01  ? 170 MET A CE  1 
ATOM   1212  N N   . PRO A 1 171 ? 120.748 112.315 99.254  1.00 30.88  ? 171 PRO A N   1 
ATOM   1213  C CA  . PRO A 1 171 ? 119.876 112.643 100.383 1.00 30.88  ? 171 PRO A CA  1 
ATOM   1214  C C   . PRO A 1 171 ? 120.307 111.963 101.672 1.00 30.88  ? 171 PRO A C   1 
ATOM   1215  O O   . PRO A 1 171 ? 120.950 110.913 101.676 1.00 30.88  ? 171 PRO A O   1 
ATOM   1216  C CB  . PRO A 1 171 ? 118.505 112.120 99.927  1.00 30.88  ? 171 PRO A CB  1 
ATOM   1217  C CG  . PRO A 1 171 ? 118.777 111.200 98.754  1.00 30.88  ? 171 PRO A CG  1 
ATOM   1218  C CD  . PRO A 1 171 ? 120.251 111.159 98.496  1.00 30.88  ? 171 PRO A CD  1 
ATOM   1219  N N   . ASN A 1 172 ? 119.933 112.587 102.784 1.00 30.66  ? 172 ASN A N   1 
ATOM   1220  C CA  . ASN A 1 172 ? 120.203 112.053 104.116 1.00 30.66  ? 172 ASN A CA  1 
ATOM   1221  C C   . ASN A 1 172 ? 118.917 111.418 104.634 1.00 30.66  ? 172 ASN A C   1 
ATOM   1222  O O   . ASN A 1 172 ? 118.024 112.109 105.128 1.00 30.66  ? 172 ASN A O   1 
ATOM   1223  C CB  . ASN A 1 172 ? 120.705 113.145 105.053 1.00 30.66  ? 172 ASN A CB  1 
ATOM   1224  C CG  . ASN A 1 172 ? 121.161 112.601 106.396 1.00 30.66  ? 172 ASN A CG  1 
ATOM   1225  O OD1 . ASN A 1 172 ? 121.062 111.406 106.662 1.00 30.66  ? 172 ASN A OD1 1 
ATOM   1226  N ND2 . ASN A 1 172 ? 121.665 113.480 107.248 1.00 30.66  ? 172 ASN A ND2 1 
ATOM   1227  N N   . ASN A 1 173 ? 118.828 110.096 104.525 1.00 35.13  ? 173 ASN A N   1 
ATOM   1228  C CA  . ASN A 1 173 ? 117.661 109.352 104.973 1.00 35.13  ? 173 ASN A CA  1 
ATOM   1229  C C   . ASN A 1 173 ? 117.892 108.645 106.302 1.00 35.13  ? 173 ASN A C   1 
ATOM   1230  O O   . ASN A 1 173 ? 117.098 107.778 106.677 1.00 35.13  ? 173 ASN A O   1 
ATOM   1231  C CB  . ASN A 1 173 ? 117.237 108.346 103.903 1.00 35.13  ? 173 ASN A CB  1 
ATOM   1232  C CG  . ASN A 1 173 ? 116.562 109.010 102.719 1.00 35.13  ? 173 ASN A CG  1 
ATOM   1233  O OD1 . ASN A 1 173 ? 115.727 109.898 102.885 1.00 35.13  ? 173 ASN A OD1 1 
ATOM   1234  N ND2 . ASN A 1 173 ? 116.921 108.582 101.516 1.00 35.13  ? 173 ASN A ND2 1 
ATOM   1235  N N   . TYR A 1 174 ? 118.960 108.990 107.014 1.00 35.27  ? 174 TYR A N   1 
ATOM   1236  C CA  . TYR A 1 174 ? 119.233 108.457 108.339 1.00 35.27  ? 174 TYR A CA  1 
ATOM   1237  C C   . TYR A 1 174 ? 118.656 109.401 109.391 1.00 35.27  ? 174 TYR A C   1 
ATOM   1238  O O   . TYR A 1 174 ? 117.957 110.366 109.075 1.00 35.27  ? 174 TYR A O   1 
ATOM   1239  C CB  . TYR A 1 174 ? 120.734 108.257 108.525 1.00 35.27  ? 174 TYR A CB  1 
ATOM   1240  C CG  . TYR A 1 174 ? 121.358 107.313 107.528 1.00 35.27  ? 174 TYR A CG  1 
ATOM   1241  C CD1 . TYR A 1 174 ? 120.711 106.147 107.148 1.00 35.27  ? 174 TYR A CD1 1 
ATOM   1242  C CD2 . TYR A 1 174 ? 122.589 107.595 106.954 1.00 35.27  ? 174 TYR A CD2 1 
ATOM   1243  C CE1 . TYR A 1 174 ? 121.277 105.283 106.236 1.00 35.27  ? 174 TYR A CE1 1 
ATOM   1244  C CE2 . TYR A 1 174 ? 123.162 106.739 106.040 1.00 35.27  ? 174 TYR A CE2 1 
ATOM   1245  C CZ  . TYR A 1 174 ? 122.503 105.584 105.685 1.00 35.27  ? 174 TYR A CZ  1 
ATOM   1246  O OH  . TYR A 1 174 ? 123.071 104.724 104.774 1.00 35.27  ? 174 TYR A OH  1 
ATOM   1247  N N   . ASN A 1 175 ? 118.955 109.139 110.664 1.00 37.34  ? 175 ASN A N   1 
ATOM   1248  C CA  . ASN A 1 175 ? 118.503 109.993 111.756 1.00 37.34  ? 175 ASN A CA  1 
ATOM   1249  C C   . ASN A 1 175 ? 119.665 110.654 112.489 1.00 37.34  ? 175 ASN A C   1 
ATOM   1250  O O   . ASN A 1 175 ? 119.502 111.092 113.631 1.00 37.34  ? 175 ASN A O   1 
ATOM   1251  C CB  . ASN A 1 175 ? 117.637 109.200 112.737 1.00 37.34  ? 175 ASN A CB  1 
ATOM   1252  C CG  . ASN A 1 175 ? 118.261 107.880 113.129 1.00 37.34  ? 175 ASN A CG  1 
ATOM   1253  O OD1 . ASN A 1 175 ? 119.051 107.305 112.380 1.00 37.34  ? 175 ASN A OD1 1 
ATOM   1254  N ND2 . ASN A 1 175 ? 117.910 107.388 114.311 1.00 37.34  ? 175 ASN A ND2 1 
ATOM   1255  N N   . PHE A 1 176 ? 120.834 110.740 111.858 1.00 33.16  ? 176 PHE A N   1 
ATOM   1256  C CA  . PHE A 1 176 ? 121.984 111.425 112.428 1.00 33.16  ? 176 PHE A CA  1 
ATOM   1257  C C   . PHE A 1 176 ? 122.604 112.335 111.377 1.00 33.16  ? 176 PHE A C   1 
ATOM   1258  O O   . PHE A 1 176 ? 122.338 112.207 110.180 1.00 33.16  ? 176 PHE A O   1 
ATOM   1259  C CB  . PHE A 1 176 ? 123.030 110.434 112.967 1.00 33.16  ? 176 PHE A CB  1 
ATOM   1260  C CG  . PHE A 1 176 ? 123.403 109.348 111.995 1.00 33.16  ? 176 PHE A CG  1 
ATOM   1261  C CD1 . PHE A 1 176 ? 124.295 109.593 110.965 1.00 33.16  ? 176 PHE A CD1 1 
ATOM   1262  C CD2 . PHE A 1 176 ? 122.868 108.077 112.119 1.00 33.16  ? 176 PHE A CD2 1 
ATOM   1263  C CE1 . PHE A 1 176 ? 124.640 108.598 110.074 1.00 33.16  ? 176 PHE A CE1 1 
ATOM   1264  C CE2 . PHE A 1 176 ? 123.212 107.077 111.231 1.00 33.16  ? 176 PHE A CE2 1 
ATOM   1265  C CZ  . PHE A 1 176 ? 124.098 107.337 110.208 1.00 33.16  ? 176 PHE A CZ  1 
ATOM   1266  N N   . ASP A 1 177 ? 123.440 113.260 111.842 1.00 31.02  ? 177 ASP A N   1 
ATOM   1267  C CA  . ASP A 1 177 ? 124.089 114.217 110.957 1.00 31.02  ? 177 ASP A CA  1 
ATOM   1268  C C   . ASP A 1 177 ? 125.202 113.554 110.152 1.00 31.02  ? 177 ASP A C   1 
ATOM   1269  O O   . ASP A 1 177 ? 125.807 112.569 110.579 1.00 31.02  ? 177 ASP A O   1 
ATOM   1270  C CB  . ASP A 1 177 ? 124.670 115.379 111.762 1.00 31.02  ? 177 ASP A CB  1 
ATOM   1271  C CG  . ASP A 1 177 ? 123.606 116.302 112.315 1.00 31.02  ? 177 ASP A CG  1 
ATOM   1272  O OD1 . ASP A 1 177 ? 122.409 115.972 112.200 1.00 31.02  ? 177 ASP A OD1 1 
ATOM   1273  O OD2 . ASP A 1 177 ? 123.967 117.357 112.874 1.00 31.02  ? 177 ASP A OD2 1 
ATOM   1274  N N   . LYS A 1 178 ? 125.478 114.116 108.977 1.00 25.83  ? 178 LYS A N   1 
ATOM   1275  C CA  . LYS A 1 178 ? 126.577 113.677 108.127 1.00 25.83  ? 178 LYS A CA  1 
ATOM   1276  C C   . LYS A 1 178 ? 127.572 114.814 107.951 1.00 25.83  ? 178 LYS A C   1 
ATOM   1277  O O   . LYS A 1 178 ? 127.179 115.972 107.806 1.00 25.83  ? 178 LYS A O   1 
ATOM   1278  C CB  . LYS A 1 178 ? 126.085 113.227 106.751 1.00 25.83  ? 178 LYS A CB  1 
ATOM   1279  C CG  . LYS A 1 178 ? 125.259 111.961 106.726 1.00 25.83  ? 178 LYS A CG  1 
ATOM   1280  C CD  . LYS A 1 178 ? 124.748 111.721 105.319 1.00 25.83  ? 178 LYS A CD  1 
ATOM   1281  C CE  . LYS A 1 178 ? 124.090 110.369 105.171 1.00 25.83  ? 178 LYS A CE  1 
ATOM   1282  N NZ  . LYS A 1 178 ? 123.819 110.055 103.744 1.00 25.83  ? 178 LYS A NZ  1 
ATOM   1283  N N   . LEU A 1 179 ? 128.859 114.482 107.961 1.00 23.79  ? 179 LEU A N   1 
ATOM   1284  C CA  . LEU A 1 179 ? 129.925 115.445 107.704 1.00 23.79  ? 179 LEU A CA  1 
ATOM   1285  C C   . LEU A 1 179 ? 130.646 115.049 106.422 1.00 23.79  ? 179 LEU A C   1 
ATOM   1286  O O   . LEU A 1 179 ? 131.122 113.917 106.299 1.00 23.79  ? 179 LEU A O   1 
ATOM   1287  C CB  . LEU A 1 179 ? 130.902 115.513 108.877 1.00 23.79  ? 179 LEU A CB  1 
ATOM   1288  C CG  . LEU A 1 179 ? 132.130 116.413 108.705 1.00 23.79  ? 179 LEU A CG  1 
ATOM   1289  C CD1 . LEU A 1 179 ? 131.749 117.882 108.732 1.00 23.79  ? 179 LEU A CD1 1 
ATOM   1290  C CD2 . LEU A 1 179 ? 133.163 116.112 109.768 1.00 23.79  ? 179 LEU A CD2 1 
ATOM   1291  N N   . TYR A 1 180 ? 130.723 115.978 105.476 1.00 22.67  ? 180 TYR A N   1 
ATOM   1292  C CA  . TYR A 1 180 ? 131.387 115.768 104.200 1.00 22.67  ? 180 TYR A CA  1 
ATOM   1293  C C   . TYR A 1 180 ? 132.618 116.659 104.124 1.00 22.67  ? 180 TYR A C   1 
ATOM   1294  O O   . TYR A 1 180 ? 132.546 117.849 104.450 1.00 22.67  ? 180 TYR A O   1 
ATOM   1295  C CB  . TYR A 1 180 ? 130.448 116.078 103.032 1.00 22.67  ? 180 TYR A CB  1 
ATOM   1296  C CG  . TYR A 1 180 ? 129.382 115.039 102.775 1.00 22.67  ? 180 TYR A CG  1 
ATOM   1297  C CD1 . TYR A 1 180 ? 129.648 113.920 102.000 1.00 22.67  ? 180 TYR A CD1 1 
ATOM   1298  C CD2 . TYR A 1 180 ? 128.104 115.185 103.295 1.00 22.67  ? 180 TYR A CD2 1 
ATOM   1299  C CE1 . TYR A 1 180 ? 128.676 112.973 101.759 1.00 22.67  ? 180 TYR A CE1 1 
ATOM   1300  C CE2 . TYR A 1 180 ? 127.125 114.243 103.058 1.00 22.67  ? 180 TYR A CE2 1 
ATOM   1301  C CZ  . TYR A 1 180 ? 127.416 113.140 102.289 1.00 22.67  ? 180 TYR A CZ  1 
ATOM   1302  O OH  . TYR A 1 180 ? 126.445 112.200 102.051 1.00 22.67  ? 180 TYR A OH  1 
ATOM   1303  N N   . ILE A 1 181 ? 133.736 116.081 103.695 1.00 21.32  ? 181 ILE A N   1 
ATOM   1304  C CA  . ILE A 1 181 ? 134.976 116.803 103.437 1.00 21.32  ? 181 ILE A CA  1 
ATOM   1305  C C   . ILE A 1 181 ? 135.220 116.792 101.934 1.00 21.32  ? 181 ILE A C   1 
ATOM   1306  O O   . ILE A 1 181 ? 135.151 115.734 101.299 1.00 21.32  ? 181 ILE A O   1 
ATOM   1307  C CB  . ILE A 1 181 ? 136.165 116.178 104.190 1.00 21.32  ? 181 ILE A CB  1 
ATOM   1308  C CG1 . ILE A 1 181 ? 135.793 115.869 105.643 1.00 21.32  ? 181 ILE A CG1 1 
ATOM   1309  C CG2 . ILE A 1 181 ? 137.391 117.080 104.116 1.00 21.32  ? 181 ILE A CG2 1 
ATOM   1310  C CD1 . ILE A 1 181 ? 135.575 117.092 106.497 1.00 21.32  ? 181 ILE A CD1 1 
ATOM   1311  N N   . TRP A 1 182 ? 135.502 117.962 101.365 1.00 20.76  ? 182 TRP A N   1 
ATOM   1312  C CA  . TRP A 1 182 ? 135.757 118.077 99.933  1.00 20.76  ? 182 TRP A CA  1 
ATOM   1313  C C   . TRP A 1 182 ? 136.822 119.146 99.716  1.00 20.76  ? 182 TRP A C   1 
ATOM   1314  O O   . TRP A 1 182 ? 137.274 119.795 100.660 1.00 20.76  ? 182 TRP A O   1 
ATOM   1315  C CB  . TRP A 1 182 ? 134.459 118.368 99.166  1.00 20.76  ? 182 TRP A CB  1 
ATOM   1316  C CG  . TRP A 1 182 ? 133.623 119.466 99.747  1.00 20.76  ? 182 TRP A CG  1 
ATOM   1317  C CD1 . TRP A 1 182 ? 132.744 119.367 100.786 1.00 20.76  ? 182 TRP A CD1 1 
ATOM   1318  C CD2 . TRP A 1 182 ? 133.579 120.829 99.315  1.00 20.76  ? 182 TRP A CD2 1 
ATOM   1319  N NE1 . TRP A 1 182 ? 132.164 120.584 101.032 1.00 20.76  ? 182 TRP A NE1 1 
ATOM   1320  C CE2 . TRP A 1 182 ? 132.658 121.500 100.142 1.00 20.76  ? 182 TRP A CE2 1 
ATOM   1321  C CE3 . TRP A 1 182 ? 134.235 121.550 98.312  1.00 20.76  ? 182 TRP A CE3 1 
ATOM   1322  C CZ2 . TRP A 1 182 ? 132.375 122.855 99.997  1.00 20.76  ? 182 TRP A CZ2 1 
ATOM   1323  C CZ3 . TRP A 1 182 ? 133.951 122.894 98.169  1.00 20.76  ? 182 TRP A CZ3 1 
ATOM   1324  C CH2 . TRP A 1 182 ? 133.030 123.533 99.007  1.00 20.76  ? 182 TRP A CH2 1 
ATOM   1325  N N   . GLY A 1 183 ? 137.237 119.324 98.460  1.00 21.87  ? 183 GLY A N   1 
ATOM   1326  C CA  . GLY A 1 183 ? 138.331 120.232 98.179  1.00 21.87  ? 183 GLY A CA  1 
ATOM   1327  C C   . GLY A 1 183 ? 138.269 120.866 96.806  1.00 21.87  ? 183 GLY A C   1 
ATOM   1328  O O   . GLY A 1 183 ? 137.457 120.504 95.955  1.00 21.87  ? 183 GLY A O   1 
ATOM   1329  N N   . VAL A 1 184 ? 139.153 121.844 96.614  1.00 23.60  ? 184 VAL A N   1 
ATOM   1330  C CA  . VAL A 1 184 ? 139.306 122.570 95.356  1.00 23.60  ? 184 VAL A CA  1 
ATOM   1331  C C   . VAL A 1 184 ? 140.790 122.638 95.019  1.00 23.60  ? 184 VAL A C   1 
ATOM   1332  O O   . VAL A 1 184 ? 141.618 122.914 95.891  1.00 23.60  ? 184 VAL A O   1 
ATOM   1333  C CB  . VAL A 1 184 ? 138.705 123.993 95.432  1.00 23.60  ? 184 VAL A CB  1 
ATOM   1334  C CG1 . VAL A 1 184 ? 138.824 124.703 94.092  1.00 23.60  ? 184 VAL A CG1 1 
ATOM   1335  C CG2 . VAL A 1 184 ? 137.256 123.957 95.894  1.00 23.60  ? 184 VAL A CG2 1 
ATOM   1336  N N   . HIS A 1 185 ? 141.127 122.399 93.755  1.00 24.84  ? 185 HIS A N   1 
ATOM   1337  C CA  . HIS A 1 185 ? 142.515 122.397 93.306  1.00 24.84  ? 185 HIS A CA  1 
ATOM   1338  C C   . HIS A 1 185 ? 142.879 123.728 92.659  1.00 24.84  ? 185 HIS A C   1 
ATOM   1339  O O   . HIS A 1 185 ? 142.150 124.225 91.796  1.00 24.84  ? 185 HIS A O   1 
ATOM   1340  C CB  . HIS A 1 185 ? 142.771 121.257 92.320  1.00 24.84  ? 185 HIS A CB  1 
ATOM   1341  C CG  . HIS A 1 185 ? 144.165 121.239 91.778  1.00 24.84  ? 185 HIS A CG  1 
ATOM   1342  N ND1 . HIS A 1 185 ? 144.446 121.381 90.437  1.00 24.84  ? 185 HIS A ND1 1 
ATOM   1343  C CD2 . HIS A 1 185 ? 145.360 121.106 92.399  1.00 24.84  ? 185 HIS A CD2 1 
ATOM   1344  C CE1 . HIS A 1 185 ? 145.753 121.332 90.255  1.00 24.84  ? 185 HIS A CE1 1 
ATOM   1345  N NE2 . HIS A 1 185 ? 146.330 121.167 91.431  1.00 24.84  ? 185 HIS A NE2 1 
ATOM   1346  N N   . HIS A 1 186 ? 144.013 124.292 93.076  1.00 25.57  ? 186 HIS A N   1 
ATOM   1347  C CA  . HIS A 1 186 ? 144.564 125.523 92.521  1.00 25.57  ? 186 HIS A CA  1 
ATOM   1348  C C   . HIS A 1 186 ? 145.786 125.197 91.672  1.00 25.57  ? 186 HIS A C   1 
ATOM   1349  O O   . HIS A 1 186 ? 146.836 124.822 92.224  1.00 25.57  ? 186 HIS A O   1 
ATOM   1350  C CB  . HIS A 1 186 ? 144.941 126.497 93.638  1.00 25.57  ? 186 HIS A CB  1 
ATOM   1351  C CG  . HIS A 1 186 ? 143.848 126.733 94.632  1.00 25.57  ? 186 HIS A CG  1 
ATOM   1352  N ND1 . HIS A 1 186 ? 142.739 127.500 94.350  1.00 25.57  ? 186 HIS A ND1 1 
ATOM   1353  C CD2 . HIS A 1 186 ? 143.696 126.307 95.908  1.00 25.57  ? 186 HIS A CD2 1 
ATOM   1354  C CE1 . HIS A 1 186 ? 141.949 127.534 95.408  1.00 25.57  ? 186 HIS A CE1 1 
ATOM   1355  N NE2 . HIS A 1 186 ? 142.507 126.819 96.367  1.00 25.57  ? 186 HIS A NE2 1 
ATOM   1356  N N   . PRO A 1 187 ? 145.698 125.318 90.350  1.00 27.17  ? 187 PRO A N   1 
ATOM   1357  C CA  . PRO A 1 187 ? 146.838 125.012 89.481  1.00 27.17  ? 187 PRO A CA  1 
ATOM   1358  C C   . PRO A 1 187 ? 147.852 126.150 89.458  1.00 27.17  ? 187 PRO A C   1 
ATOM   1359  O O   . PRO A 1 187 ? 147.616 127.250 89.954  1.00 27.17  ? 187 PRO A O   1 
ATOM   1360  C CB  . PRO A 1 187 ? 146.194 124.826 88.099  1.00 27.17  ? 187 PRO A CB  1 
ATOM   1361  C CG  . PRO A 1 187 ? 144.707 124.831 88.334  1.00 27.17  ? 187 PRO A CG  1 
ATOM   1362  C CD  . PRO A 1 187 ? 144.490 125.623 89.571  1.00 27.17  ? 187 PRO A CD  1 
ATOM   1363  N N   . SER A 1 188 ? 149.003 125.860 88.854  1.00 31.24  ? 188 SER A N   1 
ATOM   1364  C CA  . SER A 1 188 ? 150.097 126.821 88.815  1.00 31.24  ? 188 SER A CA  1 
ATOM   1365  C C   . SER A 1 188 ? 150.049 127.747 87.605  1.00 31.24  ? 188 SER A C   1 
ATOM   1366  O O   . SER A 1 188 ? 150.467 128.904 87.713  1.00 31.24  ? 188 SER A O   1 
ATOM   1367  C CB  . SER A 1 188 ? 151.442 126.090 88.849  1.00 31.24  ? 188 SER A CB  1 
ATOM   1368  O OG  . SER A 1 188 ? 151.532 125.129 87.815  1.00 31.24  ? 188 SER A OG  1 
ATOM   1369  N N   . THR A 1 189 ? 149.551 127.283 86.459  1.00 33.57  ? 189 THR A N   1 
ATOM   1370  C CA  . THR A 1 189 ? 149.505 128.099 85.250  1.00 33.57  ? 189 THR A CA  1 
ATOM   1371  C C   . THR A 1 189 ? 148.155 127.938 84.563  1.00 33.57  ? 189 THR A C   1 
ATOM   1372  O O   . THR A 1 189 ? 147.363 127.052 84.891  1.00 33.57  ? 189 THR A O   1 
ATOM   1373  C CB  . THR A 1 189 ? 150.628 127.736 84.264  1.00 33.57  ? 189 THR A CB  1 
ATOM   1374  O OG1 . THR A 1 189 ? 150.452 126.390 83.806  1.00 33.57  ? 189 THR A OG1 1 
ATOM   1375  C CG2 . THR A 1 189 ? 151.998 127.880 84.912  1.00 33.57  ? 189 THR A CG2 1 
ATOM   1376  N N   . ASN A 1 190 ? 147.900 128.822 83.593  1.00 36.52  ? 190 ASN A N   1 
ATOM   1377  C CA  . ASN A 1 190 ? 146.690 128.723 82.781  1.00 36.52  ? 190 ASN A CA  1 
ATOM   1378  C C   . ASN A 1 190 ? 146.733 127.500 81.874  1.00 36.52  ? 190 ASN A C   1 
ATOM   1379  O O   . ASN A 1 190 ? 145.703 126.854 81.636  1.00 36.52  ? 190 ASN A O   1 
ATOM   1380  C CB  . ASN A 1 190 ? 146.512 129.995 81.951  1.00 36.52  ? 190 ASN A CB  1 
ATOM   1381  C CG  . ASN A 1 190 ? 145.920 131.134 82.749  1.00 36.52  ? 190 ASN A CG  1 
ATOM   1382  O OD1 . ASN A 1 190 ? 145.980 131.143 83.976  1.00 36.52  ? 190 ASN A OD1 1 
ATOM   1383  N ND2 . ASN A 1 190 ? 145.350 132.109 82.054  1.00 36.52  ? 190 ASN A ND2 1 
ATOM   1384  N N   . GLN A 1 191 ? 147.917 127.177 81.351  1.00 37.22  ? 191 GLN A N   1 
ATOM   1385  C CA  . GLN A 1 191 ? 148.060 125.998 80.506  1.00 37.22  ? 191 GLN A CA  1 
ATOM   1386  C C   . GLN A 1 191 ? 147.747 124.726 81.280  1.00 37.22  ? 191 GLN A C   1 
ATOM   1387  O O   . GLN A 1 191 ? 147.077 123.828 80.763  1.00 37.22  ? 191 GLN A O   1 
ATOM   1388  C CB  . GLN A 1 191 ? 149.469 125.941 79.919  1.00 37.22  ? 191 GLN A CB  1 
ATOM   1389  C CG  . GLN A 1 191 ? 149.717 124.745 79.018  1.00 37.22  ? 191 GLN A CG  1 
ATOM   1390  C CD  . GLN A 1 191 ? 149.175 124.950 77.618  1.00 37.22  ? 191 GLN A CD  1 
ATOM   1391  O OE1 . GLN A 1 191 ? 147.965 124.931 77.398  1.00 37.22  ? 191 GLN A OE1 1 
ATOM   1392  N NE2 . GLN A 1 191 ? 150.073 125.147 76.661  1.00 37.22  ? 191 GLN A NE2 1 
ATOM   1393  N N   . GLU A 1 192 ? 148.220 124.634 82.525  1.00 35.46  ? 192 GLU A N   1 
ATOM   1394  C CA  . GLU A 1 192 ? 147.882 123.489 83.365  1.00 35.46  ? 192 GLU A CA  1 
ATOM   1395  C C   . GLU A 1 192 ? 146.383 123.422 83.621  1.00 35.46  ? 192 GLU A C   1 
ATOM   1396  O O   . GLU A 1 192 ? 145.787 122.337 83.596  1.00 35.46  ? 192 GLU A O   1 
ATOM   1397  C CB  . GLU A 1 192 ? 148.650 123.565 84.685  1.00 35.46  ? 192 GLU A CB  1 
ATOM   1398  C CG  . GLU A 1 192 ? 148.701 122.263 85.459  1.00 35.46  ? 192 GLU A CG  1 
ATOM   1399  C CD  . GLU A 1 192 ? 149.631 122.331 86.655  1.00 35.46  ? 192 GLU A CD  1 
ATOM   1400  O OE1 . GLU A 1 192 ? 149.401 123.172 87.548  1.00 35.46  ? 192 GLU A OE1 1 
ATOM   1401  O OE2 . GLU A 1 192 ? 150.598 121.543 86.699  1.00 35.46  ? 192 GLU A OE2 1 
ATOM   1402  N N   . GLN A 1 193 ? 145.761 124.577 83.870  1.00 32.08  ? 193 GLN A N   1 
ATOM   1403  C CA  . GLN A 1 193 ? 144.317 124.625 84.067  1.00 32.08  ? 193 GLN A CA  1 
ATOM   1404  C C   . GLN A 1 193 ? 143.582 124.041 82.870  1.00 32.08  ? 193 GLN A C   1 
ATOM   1405  O O   . GLN A 1 193 ? 142.710 123.183 83.031  1.00 32.08  ? 193 GLN A O   1 
ATOM   1406  C CB  . GLN A 1 193 ? 143.867 126.063 84.328  1.00 32.08  ? 193 GLN A CB  1 
ATOM   1407  C CG  . GLN A 1 193 ? 142.375 126.302 84.147  1.00 32.08  ? 193 GLN A CG  1 
ATOM   1408  C CD  . GLN A 1 193 ? 141.538 125.790 85.306  1.00 32.08  ? 193 GLN A CD  1 
ATOM   1409  O OE1 . GLN A 1 193 ? 141.972 125.800 86.455  1.00 32.08  ? 193 GLN A OE1 1 
ATOM   1410  N NE2 . GLN A 1 193 ? 140.329 125.337 85.004  1.00 32.08  ? 193 GLN A NE2 1 
ATOM   1411  N N   . THR A 1 194 ? 143.938 124.473 81.655  1.00 35.03  ? 194 THR A N   1 
ATOM   1412  C CA  . THR A 1 194 ? 143.257 123.937 80.477  1.00 35.03  ? 194 THR A CA  1 
ATOM   1413  C C   . THR A 1 194 ? 143.626 122.480 80.218  1.00 35.03  ? 194 THR A C   1 
ATOM   1414  O O   . THR A 1 194 ? 142.821 121.734 79.652  1.00 35.03  ? 194 THR A O   1 
ATOM   1415  C CB  . THR A 1 194 ? 143.558 124.781 79.236  1.00 35.03  ? 194 THR A CB  1 
ATOM   1416  O OG1 . THR A 1 194 ? 144.973 124.952 79.091  1.00 35.03  ? 194 THR A OG1 1 
ATOM   1417  C CG2 . THR A 1 194 ? 142.891 126.138 79.339  1.00 35.03  ? 194 THR A CG2 1 
ATOM   1418  N N   . ASN A 1 195 ? 144.822 122.053 80.627  1.00 36.08  ? 195 ASN A N   1 
ATOM   1419  C CA  . ASN A 1 195 ? 145.244 120.680 80.372  1.00 36.08  ? 195 ASN A CA  1 
ATOM   1420  C C   . ASN A 1 195 ? 144.498 119.689 81.258  1.00 36.08  ? 195 ASN A C   1 
ATOM   1421  O O   . ASN A 1 195 ? 144.129 118.601 80.802  1.00 36.08  ? 195 ASN A O   1 
ATOM   1422  C CB  . ASN A 1 195 ? 146.752 120.547 80.578  1.00 36.08  ? 195 ASN A CB  1 
ATOM   1423  C CG  . ASN A 1 195 ? 147.552 121.092 79.412  1.00 36.08  ? 195 ASN A CG  1 
ATOM   1424  O OD1 . ASN A 1 195 ? 147.012 121.345 78.335  1.00 36.08  ? 195 ASN A OD1 1 
ATOM   1425  N ND2 . ASN A 1 195 ? 148.848 121.277 79.622  1.00 36.08  ? 195 ASN A ND2 1 
ATOM   1426  N N   . LEU A 1 196 ? 144.274 120.036 82.526  1.00 32.21  ? 196 LEU A N   1 
ATOM   1427  C CA  . LEU A 1 196 ? 143.566 119.128 83.423  1.00 32.21  ? 196 LEU A CA  1 
ATOM   1428  C C   . LEU A 1 196 ? 142.052 119.244 83.297  1.00 32.21  ? 196 LEU A C   1 
ATOM   1429  O O   . LEU A 1 196 ? 141.353 118.227 83.251  1.00 32.21  ? 196 LEU A O   1 
ATOM   1430  C CB  . LEU A 1 196 ? 143.975 119.381 84.876  1.00 32.21  ? 196 LEU A CB  1 
ATOM   1431  C CG  . LEU A 1 196 ? 145.455 119.285 85.248  1.00 32.21  ? 196 LEU A CG  1 
ATOM   1432  C CD1 . LEU A 1 196 ? 145.604 119.213 86.757  1.00 32.21  ? 196 LEU A CD1 1 
ATOM   1433  C CD2 . LEU A 1 196 ? 146.117 118.092 84.584  1.00 32.21  ? 196 LEU A CD2 1 
ATOM   1434  N N   . TYR A 1 197 ? 141.534 120.467 83.256  1.00 30.71  ? 197 TYR A N   1 
ATOM   1435  C CA  . TYR A 1 197 ? 140.107 120.735 83.134  1.00 30.71  ? 197 TYR A CA  1 
ATOM   1436  C C   . TYR A 1 197 ? 139.904 121.603 81.903  1.00 30.71  ? 197 TYR A C   1 
ATOM   1437  O O   . TYR A 1 197 ? 140.550 122.645 81.764  1.00 30.71  ? 197 TYR A O   1 
ATOM   1438  C CB  . TYR A 1 197 ? 139.578 121.418 84.395  1.00 30.71  ? 197 TYR A CB  1 
ATOM   1439  C CG  . TYR A 1 197 ? 140.317 120.988 85.643  1.00 30.71  ? 197 TYR A CG  1 
ATOM   1440  C CD1 . TYR A 1 197 ? 140.076 119.749 86.222  1.00 30.71  ? 197 TYR A CD1 1 
ATOM   1441  C CD2 . TYR A 1 197 ? 141.273 121.807 86.227  1.00 30.71  ? 197 TYR A CD2 1 
ATOM   1442  C CE1 . TYR A 1 197 ? 140.753 119.345 87.352  1.00 30.71  ? 197 TYR A CE1 1 
ATOM   1443  C CE2 . TYR A 1 197 ? 141.956 121.411 87.359  1.00 30.71  ? 197 TYR A CE2 1 
ATOM   1444  C CZ  . TYR A 1 197 ? 141.691 120.179 87.917  1.00 30.71  ? 197 TYR A CZ  1 
ATOM   1445  O OH  . TYR A 1 197 ? 142.368 119.780 89.042  1.00 30.71  ? 197 TYR A OH  1 
ATOM   1446  N N   . VAL A 1 198 ? 139.010 121.180 81.013  1.00 31.82  ? 198 VAL A N   1 
ATOM   1447  C CA  . VAL A 1 198 ? 138.940 121.797 79.690  1.00 31.82  ? 198 VAL A CA  1 
ATOM   1448  C C   . VAL A 1 198 ? 138.605 123.281 79.798  1.00 31.82  ? 198 VAL A C   1 
ATOM   1449  O O   . VAL A 1 198 ? 139.148 124.109 79.057  1.00 31.82  ? 198 VAL A O   1 
ATOM   1450  C CB  . VAL A 1 198 ? 137.929 121.041 78.811  1.00 31.82  ? 198 VAL A CB  1 
ATOM   1451  C CG1 . VAL A 1 198 ? 137.729 121.752 77.487  1.00 31.82  ? 198 VAL A CG1 1 
ATOM   1452  C CG2 . VAL A 1 198 ? 138.405 119.615 78.593  1.00 31.82  ? 198 VAL A CG2 1 
ATOM   1453  N N   . GLN A 1 199 ? 137.727 123.642 80.726  1.00 32.71  ? 199 GLN A N   1 
ATOM   1454  C CA  . GLN A 1 199 ? 137.310 125.028 80.868  1.00 32.71  ? 199 GLN A CA  1 
ATOM   1455  C C   . GLN A 1 199 ? 138.448 125.893 81.403  1.00 32.71  ? 199 GLN A C   1 
ATOM   1456  O O   . GLN A 1 199 ? 139.280 125.449 82.198  1.00 32.71  ? 199 GLN A O   1 
ATOM   1457  C CB  . GLN A 1 199 ? 136.095 125.122 81.790  1.00 32.71  ? 199 GLN A CB  1 
ATOM   1458  C CG  . GLN A 1 199 ? 134.786 124.719 81.129  1.00 32.71  ? 199 GLN A CG  1 
ATOM   1459  C CD  . GLN A 1 199 ? 134.710 123.237 80.822  1.00 32.71  ? 199 GLN A CD  1 
ATOM   1460  O OE1 . GLN A 1 199 ? 134.775 122.400 81.719  1.00 32.71  ? 199 GLN A OE1 1 
ATOM   1461  N NE2 . GLN A 1 199 ? 134.579 122.905 79.546  1.00 32.71  ? 199 GLN A NE2 1 
ATOM   1462  N N   . ALA A 1 200 ? 138.476 127.147 80.951  1.00 35.22  ? 200 ALA A N   1 
ATOM   1463  C CA  . ALA A 1 200 ? 139.521 128.086 81.339  1.00 35.22  ? 200 ALA A CA  1 
ATOM   1464  C C   . ALA A 1 200 ? 139.354 128.616 82.756  1.00 35.22  ? 200 ALA A C   1 
ATOM   1465  O O   . ALA A 1 200 ? 140.299 129.200 83.294  1.00 35.22  ? 200 ALA A O   1 
ATOM   1466  C CB  . ALA A 1 200 ? 139.565 129.258 80.358  1.00 35.22  ? 200 ALA A CB  1 
ATOM   1467  N N   . SER A 1 201 ? 138.187 128.436 83.367  1.00 35.73  ? 201 SER A N   1 
ATOM   1468  C CA  . SER A 1 201 ? 137.965 128.880 84.740  1.00 35.73  ? 201 SER A CA  1 
ATOM   1469  C C   . SER A 1 201 ? 136.954 127.940 85.380  1.00 35.73  ? 201 SER A C   1 
ATOM   1470  O O   . SER A 1 201 ? 135.785 127.921 84.983  1.00 35.73  ? 201 SER A O   1 
ATOM   1471  C CB  . SER A 1 201 ? 137.479 130.325 84.778  1.00 35.73  ? 201 SER A CB  1 
ATOM   1472  O OG  . SER A 1 201 ? 136.787 130.596 85.983  1.00 35.73  ? 201 SER A OG  1 
ATOM   1473  N N   . GLY A 1 202 ? 137.401 127.166 86.367  1.00 31.96  ? 202 GLY A N   1 
ATOM   1474  C CA  . GLY A 1 202 ? 136.539 126.229 87.049  1.00 31.96  ? 202 GLY A CA  1 
ATOM   1475  C C   . GLY A 1 202 ? 135.693 126.884 88.122  1.00 31.96  ? 202 GLY A C   1 
ATOM   1476  O O   . GLY A 1 202 ? 135.788 128.078 88.400  1.00 31.96  ? 202 GLY A O   1 
ATOM   1477  N N   . ARG A 1 203 ? 134.846 126.065 88.741  1.00 30.04  ? 203 ARG A N   1 
ATOM   1478  C CA  . ARG A 1 203 ? 133.921 126.524 89.767  1.00 30.04  ? 203 ARG A CA  1 
ATOM   1479  C C   . ARG A 1 203 ? 133.366 125.314 90.501  1.00 30.04  ? 203 ARG A C   1 
ATOM   1480  O O   . ARG A 1 203 ? 133.056 124.297 89.872  1.00 30.04  ? 203 ARG A O   1 
ATOM   1481  C CB  . ARG A 1 203 ? 132.779 127.346 89.149  1.00 30.04  ? 203 ARG A CB  1 
ATOM   1482  C CG  . ARG A 1 203 ? 131.680 127.717 90.114  1.00 30.04  ? 203 ARG A CG  1 
ATOM   1483  C CD  . ARG A 1 203 ? 130.482 128.323 89.395  1.00 30.04  ? 203 ARG A CD  1 
ATOM   1484  N NE  . ARG A 1 203 ? 130.028 127.512 88.272  1.00 30.04  ? 203 ARG A NE  1 
ATOM   1485  C CZ  . ARG A 1 203 ? 129.327 126.391 88.385  1.00 30.04  ? 203 ARG A CZ  1 
ATOM   1486  N NH1 . ARG A 1 203 ? 128.998 125.894 89.566  1.00 30.04  ? 203 ARG A NH1 1 
ATOM   1487  N NH2 . ARG A 1 203 ? 128.950 125.749 87.284  1.00 30.04  ? 203 ARG A NH2 1 
ATOM   1488  N N   . VAL A 1 204 ? 133.239 125.428 91.825  1.00 27.50  ? 204 VAL A N   1 
ATOM   1489  C CA  . VAL A 1 204 ? 132.677 124.361 92.650  1.00 27.50  ? 204 VAL A CA  1 
ATOM   1490  C C   . VAL A 1 204 ? 131.576 124.942 93.528  1.00 27.50  ? 204 VAL A C   1 
ATOM   1491  O O   . VAL A 1 204 ? 131.803 125.926 94.238  1.00 27.50  ? 204 VAL A O   1 
ATOM   1492  C CB  . VAL A 1 204 ? 133.758 123.684 93.518  1.00 27.50  ? 204 VAL A CB  1 
ATOM   1493  C CG1 . VAL A 1 204 ? 133.158 122.561 94.347  1.00 27.50  ? 204 VAL A CG1 1 
ATOM   1494  C CG2 . VAL A 1 204 ? 134.892 123.162 92.650  1.00 27.50  ? 204 VAL A CG2 1 
ATOM   1495  N N   . THR A 1 205 ? 130.392 124.326 93.500  1.00 28.26  ? 205 THR A N   1 
ATOM   1496  C CA  . THR A 1 205 ? 129.266 124.748 94.325  1.00 28.26  ? 205 THR A CA  1 
ATOM   1497  C C   . THR A 1 205 ? 128.731 123.553 95.101  1.00 28.26  ? 205 THR A C   1 
ATOM   1498  O O   . THR A 1 205 ? 128.395 122.523 94.509  1.00 28.26  ? 205 THR A O   1 
ATOM   1499  C CB  . THR A 1 205 ? 128.144 125.361 93.473  1.00 28.26  ? 205 THR A CB  1 
ATOM   1500  O OG1 . THR A 1 205 ? 128.679 126.399 92.644  1.00 28.26  ? 205 THR A OG1 1 
ATOM   1501  C CG2 . THR A 1 205 ? 127.053 125.940 94.357  1.00 28.26  ? 205 THR A CG2 1 
ATOM   1502  N N   . VAL A 1 206 ? 128.649 123.694 96.421  1.00 26.31  ? 206 VAL A N   1 
ATOM   1503  C CA  . VAL A 1 206 ? 128.152 122.649 97.309  1.00 26.31  ? 206 VAL A CA  1 
ATOM   1504  C C   . VAL A 1 206 ? 127.049 123.251 98.166  1.00 26.31  ? 206 VAL A C   1 
ATOM   1505  O O   . VAL A 1 206 ? 127.267 124.268 98.833  1.00 26.31  ? 206 VAL A O   1 
ATOM   1506  C CB  . VAL A 1 206 ? 129.275 122.069 98.193  1.00 26.31  ? 206 VAL A CB  1 
ATOM   1507  C CG1 . VAL A 1 206 ? 128.733 120.988 99.109  1.00 26.31  ? 206 VAL A CG1 1 
ATOM   1508  C CG2 . VAL A 1 206 ? 130.405 121.527 97.333  1.00 26.31  ? 206 VAL A CG2 1 
ATOM   1509  N N   . SER A 1 207 ? 125.871 122.628 98.160  1.00 29.01  ? 207 SER A N   1 
ATOM   1510  C CA  . SER A 1 207 ? 124.735 123.266 98.813  1.00 29.01  ? 207 SER A CA  1 
ATOM   1511  C C   . SER A 1 207 ? 123.800 122.247 99.450  1.00 29.01  ? 207 SER A C   1 
ATOM   1512  O O   . SER A 1 207 ? 123.743 121.082 99.046  1.00 29.01  ? 207 SER A O   1 
ATOM   1513  C CB  . SER A 1 207 ? 123.953 124.136 97.823  1.00 29.01  ? 207 SER A CB  1 
ATOM   1514  O OG  . SER A 1 207 ? 123.551 123.382 96.696  1.00 29.01  ? 207 SER A OG  1 
ATOM   1515  N N   . THR A 1 208 ? 123.077 122.710 100.465 1.00 31.34  ? 208 THR A N   1 
ATOM   1516  C CA  . THR A 1 208 ? 121.935 122.034 101.066 1.00 31.34  ? 208 THR A CA  1 
ATOM   1517  C C   . THR A 1 208 ? 120.719 122.956 100.960 1.00 31.34  ? 208 THR A C   1 
ATOM   1518  O O   . THR A 1 208 ? 120.758 123.996 100.300 1.00 31.34  ? 208 THR A O   1 
ATOM   1519  C CB  . THR A 1 208 ? 122.216 121.647 102.522 1.00 31.34  ? 208 THR A CB  1 
ATOM   1520  O OG1 . THR A 1 208 ? 122.400 122.829 103.308 1.00 31.34  ? 208 THR A OG1 1 
ATOM   1521  C CG2 . THR A 1 208 ? 123.457 120.771 102.627 1.00 31.34  ? 208 THR A CG2 1 
ATOM   1522  N N   . ARG A 1 209 ? 119.625 122.568 101.616 1.00 33.02  ? 209 ARG A N   1 
ATOM   1523  C CA  . ARG A 1 209 ? 118.445 123.425 101.629 1.00 33.02  ? 209 ARG A CA  1 
ATOM   1524  C C   . ARG A 1 209 ? 118.636 124.670 102.486 1.00 33.02  ? 209 ARG A C   1 
ATOM   1525  O O   . ARG A 1 209 ? 117.897 125.643 102.311 1.00 33.02  ? 209 ARG A O   1 
ATOM   1526  C CB  . ARG A 1 209 ? 117.225 122.642 102.114 1.00 33.02  ? 209 ARG A CB  1 
ATOM   1527  C CG  . ARG A 1 209 ? 116.757 121.566 101.151 1.00 33.02  ? 209 ARG A CG  1 
ATOM   1528  C CD  . ARG A 1 209 ? 115.248 121.426 101.162 1.00 33.02  ? 209 ARG A CD  1 
ATOM   1529  N NE  . ARG A 1 209 ? 114.813 120.234 100.445 1.00 33.02  ? 209 ARG A NE  1 
ATOM   1530  C CZ  . ARG A 1 209 ? 114.752 119.021 100.976 1.00 33.02  ? 209 ARG A CZ  1 
ATOM   1531  N NH1 . ARG A 1 209 ? 115.061 118.807 102.244 1.00 33.02  ? 209 ARG A NH1 1 
ATOM   1532  N NH2 . ARG A 1 209 ? 114.375 117.998 100.216 1.00 33.02  ? 209 ARG A NH2 1 
ATOM   1533  N N   . ARG A 1 210 ? 119.613 124.674 103.393 1.00 36.05  ? 210 ARG A N   1 
ATOM   1534  C CA  . ARG A 1 210 ? 119.807 125.794 104.303 1.00 36.05  ? 210 ARG A CA  1 
ATOM   1535  C C   . ARG A 1 210 ? 121.166 126.473 104.187 1.00 36.05  ? 210 ARG A C   1 
ATOM   1536  O O   . ARG A 1 210 ? 121.436 127.402 104.956 1.00 36.05  ? 210 ARG A O   1 
ATOM   1537  C CB  . ARG A 1 210 ? 119.598 125.338 105.754 1.00 36.05  ? 210 ARG A CB  1 
ATOM   1538  C CG  . ARG A 1 210 ? 120.385 124.100 106.146 1.00 36.05  ? 210 ARG A CG  1 
ATOM   1539  C CD  . ARG A 1 210 ? 119.709 123.365 107.290 1.00 36.05  ? 210 ARG A CD  1 
ATOM   1540  N NE  . ARG A 1 210 ? 118.621 122.514 106.822 1.00 36.05  ? 210 ARG A NE  1 
ATOM   1541  C CZ  . ARG A 1 210 ? 117.938 121.675 107.589 1.00 36.05  ? 210 ARG A CZ  1 
ATOM   1542  N NH1 . ARG A 1 210 ? 118.200 121.550 108.880 1.00 36.05  ? 210 ARG A NH1 1 
ATOM   1543  N NH2 . ARG A 1 210 ? 116.969 120.944 107.048 1.00 36.05  ? 210 ARG A NH2 1 
ATOM   1544  N N   . SER A 1 211 ? 122.025 126.054 103.262 1.00 33.17  ? 211 SER A N   1 
ATOM   1545  C CA  . SER A 1 211 ? 123.351 126.651 103.166 1.00 33.17  ? 211 SER A CA  1 
ATOM   1546  C C   . SER A 1 211 ? 123.911 126.423 101.771 1.00 33.17  ? 211 SER A C   1 
ATOM   1547  O O   . SER A 1 211 ? 123.433 125.568 101.022 1.00 33.17  ? 211 SER A O   1 
ATOM   1548  C CB  . SER A 1 211 ? 124.298 126.081 104.227 1.00 33.17  ? 211 SER A CB  1 
ATOM   1549  O OG  . SER A 1 211 ? 124.910 124.885 103.777 1.00 33.17  ? 211 SER A OG  1 
ATOM   1550  N N   . GLN A 1 212 ? 124.936 127.202 101.435 1.00 31.08  ? 212 GLN A N   1 
ATOM   1551  C CA  . GLN A 1 212 ? 125.585 127.116 100.136 1.00 31.08  ? 212 GLN A CA  1 
ATOM   1552  C C   . GLN A 1 212 ? 127.015 127.626 100.251 1.00 31.08  ? 212 GLN A C   1 
ATOM   1553  O O   . GLN A 1 212 ? 127.309 128.507 101.062 1.00 31.08  ? 212 GLN A O   1 
ATOM   1554  C CB  . GLN A 1 212 ? 124.816 127.910 99.075  1.00 31.08  ? 212 GLN A CB  1 
ATOM   1555  C CG  . GLN A 1 212 ? 124.943 129.417 99.224  1.00 31.08  ? 212 GLN A CG  1 
ATOM   1556  C CD  . GLN A 1 212 ? 124.918 130.141 97.900  1.00 31.08  ? 212 GLN A CD  1 
ATOM   1557  O OE1 . GLN A 1 212 ? 125.637 129.780 96.969  1.00 31.08  ? 212 GLN A OE1 1 
ATOM   1558  N NE2 . GLN A 1 212 ? 124.093 131.174 97.808  1.00 31.08  ? 212 GLN A NE2 1 
ATOM   1559  N N   . GLN A 1 213 ? 127.901 127.051 99.437  1.00 29.10  ? 213 GLN A N   1 
ATOM   1560  C CA  . GLN A 1 213 ? 129.287 127.492 99.329  1.00 29.10  ? 213 GLN A CA  1 
ATOM   1561  C C   . GLN A 1 213 ? 129.719 127.388 97.874  1.00 29.10  ? 213 GLN A C   1 
ATOM   1562  O O   . GLN A 1 213 ? 129.473 126.366 97.227  1.00 29.10  ? 213 GLN A O   1 
ATOM   1563  C CB  . GLN A 1 213 ? 130.224 126.650 100.210 1.00 29.10  ? 213 GLN A CB  1 
ATOM   1564  C CG  . GLN A 1 213 ? 129.956 126.730 101.704 1.00 29.10  ? 213 GLN A CG  1 
ATOM   1565  C CD  . GLN A 1 213 ? 130.619 125.607 102.486 1.00 29.10  ? 213 GLN A CD  1 
ATOM   1566  O OE1 . GLN A 1 213 ? 130.000 124.582 102.767 1.00 29.10  ? 213 GLN A OE1 1 
ATOM   1567  N NE2 . GLN A 1 213 ? 131.879 125.802 102.850 1.00 29.10  ? 213 GLN A NE2 1 
ATOM   1568  N N   . THR A 1 214 ? 130.358 128.436 97.361  1.00 29.97  ? 214 THR A N   1 
ATOM   1569  C CA  . THR A 1 214 ? 130.902 128.428 96.008  1.00 29.97  ? 214 THR A CA  1 
ATOM   1570  C C   . THR A 1 214 ? 132.348 128.897 96.042  1.00 29.97  ? 214 THR A C   1 
ATOM   1571  O O   . THR A 1 214 ? 132.665 129.902 96.684  1.00 29.97  ? 214 THR A O   1 
ATOM   1572  C CB  . THR A 1 214 ? 130.085 129.312 95.059  1.00 29.97  ? 214 THR A CB  1 
ATOM   1573  O OG1 . THR A 1 214 ? 128.735 128.838 95.001  1.00 29.97  ? 214 THR A OG1 1 
ATOM   1574  C CG2 . THR A 1 214 ? 130.680 129.286 93.658  1.00 29.97  ? 214 THR A CG2 1 
ATOM   1575  N N   . ILE A 1 215 ? 133.216 128.169 95.343  1.00 28.18  ? 215 ILE A N   1 
ATOM   1576  C CA  . ILE A 1 215 ? 134.648 128.435 95.319  1.00 28.18  ? 215 ILE A CA  1 
ATOM   1577  C C   . ILE A 1 215 ? 135.101 128.555 93.870  1.00 28.18  ? 215 ILE A C   1 
ATOM   1578  O O   . ILE A 1 215 ? 134.790 127.690 93.039  1.00 28.18  ? 215 ILE A O   1 
ATOM   1579  C CB  . ILE A 1 215 ? 135.450 127.339 96.048  1.00 28.18  ? 215 ILE A CB  1 
ATOM   1580  C CG1 . ILE A 1 215 ? 134.860 127.061 97.432  1.00 28.18  ? 215 ILE A CG1 1 
ATOM   1581  C CG2 . ILE A 1 215 ? 136.914 127.733 96.160  1.00 28.18  ? 215 ILE A CG2 1 
ATOM   1582  C CD1 . ILE A 1 215 ? 135.072 128.172 98.427  1.00 28.18  ? 215 ILE A CD1 1 
ATOM   1583  N N   . VAL A 1 216 ? 135.819 129.629 93.577  1.00 29.62  ? 216 VAL A N   1 
ATOM   1584  C CA  . VAL A 1 216 ? 136.491 129.842 92.297  1.00 29.62  ? 216 VAL A CA  1 
ATOM   1585  C C   . VAL A 1 216 ? 137.984 129.639 92.519  1.00 29.62  ? 216 VAL A C   1 
ATOM   1586  O O   . VAL A 1 216 ? 138.557 130.282 93.405  1.00 29.62  ? 216 VAL A O   1 
ATOM   1587  C CB  . VAL A 1 216 ? 136.214 131.248 91.728  1.00 29.62  ? 216 VAL A CB  1 
ATOM   1588  C CG1 . VAL A 1 216 ? 136.950 131.448 90.412  1.00 29.62  ? 216 VAL A CG1 1 
ATOM   1589  C CG2 . VAL A 1 216 ? 134.724 131.467 91.542  1.00 29.62  ? 216 VAL A CG2 1 
ATOM   1590  N N   . PRO A 1 217 ? 138.638 128.759 91.767  1.00 28.84  ? 217 PRO A N   1 
ATOM   1591  C CA  . PRO A 1 217 ? 140.053 128.466 92.026  1.00 28.84  ? 217 PRO A CA  1 
ATOM   1592  C C   . PRO A 1 217 ? 140.971 129.628 91.667  1.00 28.84  ? 217 PRO A C   1 
ATOM   1593  O O   . PRO A 1 217 ? 140.650 130.492 90.849  1.00 28.84  ? 217 PRO A O   1 
ATOM   1594  C CB  . PRO A 1 217 ? 140.331 127.250 91.136  1.00 28.84  ? 217 PRO A CB  1 
ATOM   1595  C CG  . PRO A 1 217 ? 139.279 127.293 90.092  1.00 28.84  ? 217 PRO A CG  1 
ATOM   1596  C CD  . PRO A 1 217 ? 138.071 127.892 90.724  1.00 28.84  ? 217 PRO A CD  1 
ATOM   1597  N N   . ASN A 1 218 ? 142.140 129.628 92.303  1.00 30.42  ? 218 ASN A N   1 
ATOM   1598  C CA  . ASN A 1 218 ? 143.177 130.626 92.086  1.00 30.42  ? 218 ASN A CA  1 
ATOM   1599  C C   . ASN A 1 218 ? 144.333 130.012 91.306  1.00 30.42  ? 218 ASN A C   1 
ATOM   1600  O O   . ASN A 1 218 ? 144.716 128.866 91.551  1.00 30.42  ? 218 ASN A O   1 
ATOM   1601  C CB  . ASN A 1 218 ? 143.693 131.180 93.416  1.00 30.42  ? 218 ASN A CB  1 
ATOM   1602  C CG  . ASN A 1 218 ? 142.583 131.436 94.417  1.00 30.42  ? 218 ASN A CG  1 
ATOM   1603  O OD1 . ASN A 1 218 ? 141.544 132.002 94.080  1.00 30.42  ? 218 ASN A OD1 1 
ATOM   1604  N ND2 . ASN A 1 218 ? 142.801 131.022 95.657  1.00 30.42  ? 218 ASN A ND2 1 
ATOM   1605  N N   . ILE A 1 219 ? 144.887 130.775 90.368  1.00 30.34  ? 219 ILE A N   1 
ATOM   1606  C CA  . ILE A 1 219 ? 145.973 130.311 89.513  1.00 30.34  ? 219 ILE A CA  1 
ATOM   1607  C C   . ILE A 1 219 ? 147.213 131.149 89.798  1.00 30.34  ? 219 ILE A C   1 
ATOM   1608  O O   . ILE A 1 219 ? 147.120 132.370 89.958  1.00 30.34  ? 219 ILE A O   1 
ATOM   1609  C CB  . ILE A 1 219 ? 145.581 130.380 88.021  1.00 30.34  ? 219 ILE A CB  1 
ATOM   1610  C CG1 . ILE A 1 219 ? 144.512 129.332 87.709  1.00 30.34  ? 219 ILE A CG1 1 
ATOM   1611  C CG2 . ILE A 1 219 ? 146.790 130.165 87.126  1.00 30.34  ? 219 ILE A CG2 1 
ATOM   1612  C CD1 . ILE A 1 219 ? 143.690 129.638 86.483  1.00 30.34  ? 219 ILE A CD1 1 
ATOM   1613  N N   . GLY A 1 220 ? 148.360 130.494 89.887  1.00 29.08  ? 220 GLY A N   1 
ATOM   1614  C CA  . GLY A 1 220 ? 149.617 131.183 90.100  1.00 29.08  ? 220 GLY A CA  1 
ATOM   1615  C C   . GLY A 1 220 ? 150.689 130.250 90.608  1.00 29.08  ? 220 GLY A C   1 
ATOM   1616  O O   . GLY A 1 220 ? 150.423 129.210 91.209  1.00 29.08  ? 220 GLY A O   1 
ATOM   1617  N N   . SER A 1 221 ? 151.939 130.638 90.358  1.00 29.45  ? 221 SER A N   1 
ATOM   1618  C CA  . SER A 1 221 ? 153.082 129.854 90.807  1.00 29.45  ? 221 SER A CA  1 
ATOM   1619  C C   . SER A 1 221 ? 153.314 130.033 92.301  1.00 29.45  ? 221 SER A C   1 
ATOM   1620  O O   . SER A 1 221 ? 153.099 131.113 92.855  1.00 29.45  ? 221 SER A O   1 
ATOM   1621  C CB  . SER A 1 221 ? 154.343 130.244 90.040  1.00 29.45  ? 221 SER A CB  1 
ATOM   1622  O OG  . SER A 1 221 ? 154.249 129.890 88.674  1.00 29.45  ? 221 SER A OG  1 
ATOM   1623  N N   . ARG A 1 222 ? 153.762 128.964 92.945  1.00 27.69  ? 222 ARG A N   1 
ATOM   1624  C CA  . ARG A 1 222 ? 154.012 128.915 94.376  1.00 27.69  ? 222 ARG A CA  1 
ATOM   1625  C C   . ARG A 1 222 ? 155.301 128.144 94.613  1.00 27.69  ? 222 ARG A C   1 
ATOM   1626  O O   . ARG A 1 222 ? 155.774 127.433 93.720  1.00 27.69  ? 222 ARG A O   1 
ATOM   1627  C CB  . ARG A 1 222 ? 152.843 128.254 95.119  1.00 27.69  ? 222 ARG A CB  1 
ATOM   1628  C CG  . ARG A 1 222 ? 151.584 129.092 95.152  1.00 27.69  ? 222 ARG A CG  1 
ATOM   1629  C CD  . ARG A 1 222 ? 150.352 128.223 95.168  1.00 27.69  ? 222 ARG A CD  1 
ATOM   1630  N NE  . ARG A 1 222 ? 149.165 128.927 94.704  1.00 27.69  ? 222 ARG A NE  1 
ATOM   1631  C CZ  . ARG A 1 222 ? 148.386 128.503 93.719  1.00 27.69  ? 222 ARG A CZ  1 
ATOM   1632  N NH1 . ARG A 1 222 ? 148.661 127.397 93.049  1.00 27.69  ? 222 ARG A NH1 1 
ATOM   1633  N NH2 . ARG A 1 222 ? 147.306 129.208 93.397  1.00 27.69  ? 222 ARG A NH2 1 
ATOM   1634  N N   . PRO A 1 223 ? 155.911 128.286 95.794  1.00 28.83  ? 223 PRO A N   1 
ATOM   1635  C CA  . PRO A 1 223 ? 157.140 127.530 96.076  1.00 28.83  ? 223 PRO A CA  1 
ATOM   1636  C C   . PRO A 1 223 ? 156.906 126.027 96.016  1.00 28.83  ? 223 PRO A C   1 
ATOM   1637  O O   . PRO A 1 223 ? 155.853 125.526 96.412  1.00 28.83  ? 223 PRO A O   1 
ATOM   1638  C CB  . PRO A 1 223 ? 157.522 127.981 97.491  1.00 28.83  ? 223 PRO A CB  1 
ATOM   1639  C CG  . PRO A 1 223 ? 156.802 129.250 97.710  1.00 28.83  ? 223 PRO A CG  1 
ATOM   1640  C CD  . PRO A 1 223 ? 155.551 129.184 96.905  1.00 28.83  ? 223 PRO A CD  1 
ATOM   1641  N N   . TRP A 1 224 ? 157.908 125.309 95.511  1.00 30.65  ? 224 TRP A N   1 
ATOM   1642  C CA  . TRP A 1 224 ? 157.816 123.859 95.399  1.00 30.65  ? 224 TRP A CA  1 
ATOM   1643  C C   . TRP A 1 224 ? 157.710 123.211 96.774  1.00 30.65  ? 224 TRP A C   1 
ATOM   1644  O O   . TRP A 1 224 ? 158.495 123.507 97.677  1.00 30.65  ? 224 TRP A O   1 
ATOM   1645  C CB  . TRP A 1 224 ? 159.038 123.309 94.665  1.00 30.65  ? 224 TRP A CB  1 
ATOM   1646  C CG  . TRP A 1 224 ? 158.880 123.200 93.185  1.00 30.65  ? 224 TRP A CG  1 
ATOM   1647  C CD1 . TRP A 1 224 ? 158.085 123.964 92.385  1.00 30.65  ? 224 TRP A CD1 1 
ATOM   1648  C CD2 . TRP A 1 224 ? 159.544 122.273 92.323  1.00 30.65  ? 224 TRP A CD2 1 
ATOM   1649  N NE1 . TRP A 1 224 ? 158.210 123.568 91.078  1.00 30.65  ? 224 TRP A NE1 1 
ATOM   1650  C CE2 . TRP A 1 224 ? 159.100 122.529 91.013  1.00 30.65  ? 224 TRP A CE2 1 
ATOM   1651  C CE3 . TRP A 1 224 ? 160.471 121.248 92.532  1.00 30.65  ? 224 TRP A CE3 1 
ATOM   1652  C CZ2 . TRP A 1 224 ? 159.551 121.799 89.916  1.00 30.65  ? 224 TRP A CZ2 1 
ATOM   1653  C CZ3 . TRP A 1 224 ? 160.916 120.525 91.443  1.00 30.65  ? 224 TRP A CZ3 1 
ATOM   1654  C CH2 . TRP A 1 224 ? 160.457 120.804 90.152  1.00 30.65  ? 224 TRP A CH2 1 
ATOM   1655  N N   . VAL A 1 225 ? 156.735 122.320 96.927  1.00 27.44  ? 225 VAL A N   1 
ATOM   1656  C CA  . VAL A 1 225 ? 156.622 121.455 98.097  1.00 27.44  ? 225 VAL A CA  1 
ATOM   1657  C C   . VAL A 1 225 ? 156.504 120.029 97.580  1.00 27.44  ? 225 VAL A C   1 
ATOM   1658  O O   . VAL A 1 225 ? 155.509 119.682 96.933  1.00 27.44  ? 225 VAL A O   1 
ATOM   1659  C CB  . VAL A 1 225 ? 155.427 121.815 98.990  1.00 27.44  ? 225 VAL A CB  1 
ATOM   1660  C CG1 . VAL A 1 225 ? 155.333 120.849 100.158 1.00 27.44  ? 225 VAL A CG1 1 
ATOM   1661  C CG2 . VAL A 1 225 ? 155.550 123.239 99.494  1.00 27.44  ? 225 VAL A CG2 1 
ATOM   1662  N N   . ARG A 1 226 ? 157.516 119.208 97.862  1.00 27.24  ? 226 ARG A N   1 
ATOM   1663  C CA  . ARG A 1 226 ? 157.601 117.840 97.349  1.00 27.24  ? 226 ARG A CA  1 
ATOM   1664  C C   . ARG A 1 226 ? 157.423 117.806 95.832  1.00 27.24  ? 226 ARG A C   1 
ATOM   1665  O O   . ARG A 1 226 ? 156.760 116.928 95.279  1.00 27.24  ? 226 ARG A O   1 
ATOM   1666  C CB  . ARG A 1 226 ? 156.598 116.920 98.051  1.00 27.24  ? 226 ARG A CB  1 
ATOM   1667  C CG  . ARG A 1 226 ? 156.967 116.621 99.500  1.00 27.24  ? 226 ARG A CG  1 
ATOM   1668  C CD  . ARG A 1 226 ? 155.970 115.695 100.185 1.00 27.24  ? 226 ARG A CD  1 
ATOM   1669  N NE  . ARG A 1 226 ? 154.773 116.390 100.642 1.00 27.24  ? 226 ARG A NE  1 
ATOM   1670  C CZ  . ARG A 1 226 ? 154.733 117.225 101.671 1.00 27.24  ? 226 ARG A CZ  1 
ATOM   1671  N NH1 . ARG A 1 226 ? 155.813 117.499 102.382 1.00 27.24  ? 226 ARG A NH1 1 
ATOM   1672  N NH2 . ARG A 1 226 ? 153.580 117.801 101.995 1.00 27.24  ? 226 ARG A NH2 1 
ATOM   1673  N N   . GLY A 1 227 ? 158.029 118.781 95.155  1.00 27.70  ? 227 GLY A N   1 
ATOM   1674  C CA  . GLY A 1 227 ? 158.036 118.842 93.710  1.00 27.70  ? 227 GLY A CA  1 
ATOM   1675  C C   . GLY A 1 227 ? 156.855 119.532 93.060  1.00 27.70  ? 227 GLY A C   1 
ATOM   1676  O O   . GLY A 1 227 ? 156.833 119.647 91.830  1.00 27.70  ? 227 GLY A O   1 
ATOM   1677  N N   . GLN A 1 228 ? 155.881 120.006 93.832  1.00 28.13  ? 228 GLN A N   1 
ATOM   1678  C CA  . GLN A 1 228 ? 154.637 120.527 93.281  1.00 28.13  ? 228 GLN A CA  1 
ATOM   1679  C C   . GLN A 1 228 ? 154.457 121.995 93.638  1.00 28.13  ? 228 GLN A C   1 
ATOM   1680  O O   . GLN A 1 228 ? 154.700 122.402 94.776  1.00 28.13  ? 228 GLN A O   1 
ATOM   1681  C CB  . GLN A 1 228 ? 153.431 119.726 93.786  1.00 28.13  ? 228 GLN A CB  1 
ATOM   1682  C CG  . GLN A 1 228 ? 153.529 118.236 93.541  1.00 28.13  ? 228 GLN A CG  1 
ATOM   1683  C CD  . GLN A 1 228 ? 153.724 117.899 92.080  1.00 28.13  ? 228 GLN A CD  1 
ATOM   1684  O OE1 . GLN A 1 228 ? 153.042 118.437 91.211  1.00 28.13  ? 228 GLN A OE1 1 
ATOM   1685  N NE2 . GLN A 1 228 ? 154.658 117.000 91.801  1.00 28.13  ? 228 GLN A NE2 1 
ATOM   1686  N N   . SER A 1 229 ? 154.007 122.783 92.662  1.00 27.93  ? 229 SER A N   1 
ATOM   1687  C CA  . SER A 1 229 ? 153.694 124.186 92.888  1.00 27.93  ? 229 SER A CA  1 
ATOM   1688  C C   . SER A 1 229 ? 152.197 124.469 92.958  1.00 27.93  ? 229 SER A C   1 
ATOM   1689  O O   . SER A 1 229 ? 151.817 125.592 93.300  1.00 27.93  ? 229 SER A O   1 
ATOM   1690  C CB  . SER A 1 229 ? 154.336 125.057 91.800  1.00 27.93  ? 229 SER A CB  1 
ATOM   1691  O OG  . SER A 1 229 ? 153.849 124.719 90.517  1.00 27.93  ? 229 SER A OG  1 
ATOM   1692  N N   . GLY A 1 230 ? 151.342 123.486 92.652  1.00 24.76  ? 230 GLY A N   1 
ATOM   1693  C CA  . GLY A 1 230 ? 149.917 123.641 92.854  1.00 24.76  ? 230 GLY A CA  1 
ATOM   1694  C C   . GLY A 1 230 ? 149.512 123.391 94.297  1.00 24.76  ? 230 GLY A C   1 
ATOM   1695  O O   . GLY A 1 230 ? 150.303 122.940 95.123  1.00 24.76  ? 230 GLY A O   1 
ATOM   1696  N N   . ARG A 1 231 ? 148.251 123.695 94.608  1.00 24.40  ? 231 ARG A N   1 
ATOM   1697  C CA  . ARG A 1 231 ? 147.762 123.536 95.975  1.00 24.40  ? 231 ARG A CA  1 
ATOM   1698  C C   . ARG A 1 231 ? 146.340 122.991 95.968  1.00 24.40  ? 231 ARG A C   1 
ATOM   1699  O O   . ARG A 1 231 ? 145.686 122.911 94.929  1.00 24.40  ? 231 ARG A O   1 
ATOM   1700  C CB  . ARG A 1 231 ? 147.813 124.856 96.759  1.00 24.40  ? 231 ARG A CB  1 
ATOM   1701  C CG  . ARG A 1 231 ? 149.203 125.433 96.959  1.00 24.40  ? 231 ARG A CG  1 
ATOM   1702  C CD  . ARG A 1 231 ? 150.023 124.610 97.935  1.00 24.40  ? 231 ARG A CD  1 
ATOM   1703  N NE  . ARG A 1 231 ? 151.251 125.293 98.325  1.00 24.40  ? 231 ARG A NE  1 
ATOM   1704  C CZ  . ARG A 1 231 ? 152.432 125.109 97.750  1.00 24.40  ? 231 ARG A CZ  1 
ATOM   1705  N NH1 . ARG A 1 231 ? 152.592 124.256 96.753  1.00 24.40  ? 231 ARG A NH1 1 
ATOM   1706  N NH2 . ARG A 1 231 ? 153.479 125.801 98.187  1.00 24.40  ? 231 ARG A NH2 1 
ATOM   1707  N N   . ILE A 1 232 ? 145.865 122.606 97.151  1.00 22.74  ? 232 ILE A N   1 
ATOM   1708  C CA  . ILE A 1 232 ? 144.489 122.169 97.356  1.00 22.74  ? 232 ILE A CA  1 
ATOM   1709  C C   . ILE A 1 232 ? 143.940 122.849 98.606  1.00 22.74  ? 232 ILE A C   1 
ATOM   1710  O O   . ILE A 1 232 ? 144.643 122.979 99.611  1.00 22.74  ? 232 ILE A O   1 
ATOM   1711  C CB  . ILE A 1 232 ? 144.396 120.630 97.466  1.00 22.74  ? 232 ILE A CB  1 
ATOM   1712  C CG1 . ILE A 1 232 ? 144.500 119.990 96.080  1.00 22.74  ? 232 ILE A CG1 1 
ATOM   1713  C CG2 . ILE A 1 232 ? 143.107 120.197 98.140  1.00 22.74  ? 232 ILE A CG2 1 
ATOM   1714  C CD1 . ILE A 1 232 ? 144.505 118.488 96.097  1.00 22.74  ? 232 ILE A CD1 1 
ATOM   1715  N N   . SER A 1 233 ? 142.689 123.299 98.537  1.00 22.06  ? 233 SER A N   1 
ATOM   1716  C CA  . SER A 1 233 ? 141.985 123.886 99.671  1.00 22.06  ? 233 SER A CA  1 
ATOM   1717  C C   . SER A 1 233 ? 140.867 122.952 100.117 1.00 22.06  ? 233 SER A C   1 
ATOM   1718  O O   . SER A 1 233 ? 140.190 122.347 99.283  1.00 22.06  ? 233 SER A O   1 
ATOM   1719  C CB  . SER A 1 233 ? 141.409 125.257 99.311  1.00 22.06  ? 233 SER A CB  1 
ATOM   1720  O OG  . SER A 1 233 ? 142.353 126.286 99.534  1.00 22.06  ? 233 SER A OG  1 
ATOM   1721  N N   . ILE A 1 234 ? 140.664 122.850 101.430 1.00 20.89  ? 234 ILE A N   1 
ATOM   1722  C CA  . ILE A 1 234 ? 139.759 121.872 102.029 1.00 20.89  ? 234 ILE A CA  1 
ATOM   1723  C C   . ILE A 1 234 ? 138.570 122.587 102.663 1.00 20.89  ? 234 ILE A C   1 
ATOM   1724  O O   . ILE A 1 234 ? 138.733 123.610 103.336 1.00 20.89  ? 234 ILE A O   1 
ATOM   1725  C CB  . ILE A 1 234 ? 140.495 121.001 103.068 1.00 20.89  ? 234 ILE A CB  1 
ATOM   1726  C CG1 . ILE A 1 234 ? 141.611 120.194 102.398 1.00 20.89  ? 234 ILE A CG1 1 
ATOM   1727  C CG2 . ILE A 1 234 ? 139.527 120.075 103.791 1.00 20.89  ? 234 ILE A CG2 1 
ATOM   1728  C CD1 . ILE A 1 234 ? 141.112 119.123 101.462 1.00 20.89  ? 234 ILE A CD1 1 
ATOM   1729  N N   . TYR A 1 235 ? 137.372 122.038 102.449 1.00 21.25  ? 235 TYR A N   1 
ATOM   1730  C CA  . TYR A 1 235 ? 136.129 122.575 102.983 1.00 21.25  ? 235 TYR A CA  1 
ATOM   1731  C C   . TYR A 1 235 ? 135.277 121.430 103.518 1.00 21.25  ? 235 TYR A C   1 
ATOM   1732  O O   . TYR A 1 235 ? 135.483 120.264 103.172 1.00 21.25  ? 235 TYR A O   1 
ATOM   1733  C CB  . TYR A 1 235 ? 135.354 123.363 101.918 1.00 21.25  ? 235 TYR A CB  1 
ATOM   1734  C CG  . TYR A 1 235 ? 136.128 124.524 101.343 1.00 21.25  ? 235 TYR A CG  1 
ATOM   1735  C CD1 . TYR A 1 235 ? 136.980 124.349 100.260 1.00 21.25  ? 235 TYR A CD1 1 
ATOM   1736  C CD2 . TYR A 1 235 ? 136.020 125.794 101.891 1.00 21.25  ? 235 TYR A CD2 1 
ATOM   1737  C CE1 . TYR A 1 235 ? 137.697 125.405 99.737  1.00 21.25  ? 235 TYR A CE1 1 
ATOM   1738  C CE2 . TYR A 1 235 ? 136.732 126.854 101.376 1.00 21.25  ? 235 TYR A CE2 1 
ATOM   1739  C CZ  . TYR A 1 235 ? 137.569 126.655 100.300 1.00 21.25  ? 235 TYR A CZ  1 
ATOM   1740  O OH  . TYR A 1 235 ? 138.275 127.714 99.787  1.00 21.25  ? 235 TYR A OH  1 
ATOM   1741  N N   . TRP A 1 236 ? 134.310 121.773 104.369 1.00 23.09  ? 236 TRP A N   1 
ATOM   1742  C CA  . TRP A 1 236 ? 133.441 120.781 104.987 1.00 23.09  ? 236 TRP A CA  1 
ATOM   1743  C C   . TRP A 1 236 ? 132.000 121.273 104.997 1.00 23.09  ? 236 TRP A C   1 
ATOM   1744  O O   . TRP A 1 236 ? 131.737 122.476 104.976 1.00 23.09  ? 236 TRP A O   1 
ATOM   1745  C CB  . TRP A 1 236 ? 133.900 120.443 106.413 1.00 23.09  ? 236 TRP A CB  1 
ATOM   1746  C CG  . TRP A 1 236 ? 133.535 121.459 107.452 1.00 23.09  ? 236 TRP A CG  1 
ATOM   1747  C CD1 . TRP A 1 236 ? 132.367 121.533 108.152 1.00 23.09  ? 236 TRP A CD1 1 
ATOM   1748  C CD2 . TRP A 1 236 ? 134.354 122.532 107.925 1.00 23.09  ? 236 TRP A CD2 1 
ATOM   1749  N NE1 . TRP A 1 236 ? 132.403 122.590 109.022 1.00 23.09  ? 236 TRP A NE1 1 
ATOM   1750  C CE2 . TRP A 1 236 ? 133.613 123.221 108.903 1.00 23.09  ? 236 TRP A CE2 1 
ATOM   1751  C CE3 . TRP A 1 236 ? 135.638 122.982 107.612 1.00 23.09  ? 236 TRP A CE3 1 
ATOM   1752  C CZ2 . TRP A 1 236 ? 134.114 124.332 109.573 1.00 23.09  ? 236 TRP A CZ2 1 
ATOM   1753  C CZ3 . TRP A 1 236 ? 136.135 124.085 108.278 1.00 23.09  ? 236 TRP A CZ3 1 
ATOM   1754  C CH2 . TRP A 1 236 ? 135.374 124.748 109.246 1.00 23.09  ? 236 TRP A CH2 1 
ATOM   1755  N N   . THR A 1 237 ? 131.070 120.317 105.032 1.00 23.62  ? 237 THR A N   1 
ATOM   1756  C CA  . THR A 1 237 ? 129.639 120.597 105.019 1.00 23.62  ? 237 THR A CA  1 
ATOM   1757  C C   . THR A 1 237 ? 128.905 119.578 105.882 1.00 23.62  ? 237 THR A C   1 
ATOM   1758  O O   . THR A 1 237 ? 129.200 118.384 105.827 1.00 23.62  ? 237 THR A O   1 
ATOM   1759  C CB  . THR A 1 237 ? 129.077 120.566 103.587 1.00 23.62  ? 237 THR A CB  1 
ATOM   1760  O OG1 . THR A 1 237 ? 129.790 121.501 102.770 1.00 23.62  ? 237 THR A OG1 1 
ATOM   1761  C CG2 . THR A 1 237 ? 127.598 120.918 103.573 1.00 23.62  ? 237 THR A CG2 1 
ATOM   1762  N N   . ILE A 1 238 ? 127.937 120.045 106.667 1.00 24.97  ? 238 ILE A N   1 
ATOM   1763  C CA  . ILE A 1 238 ? 127.140 119.186 107.539 1.00 24.97  ? 238 ILE A CA  1 
ATOM   1764  C C   . ILE A 1 238 ? 125.725 119.093 106.984 1.00 24.97  ? 238 ILE A C   1 
ATOM   1765  O O   . ILE A 1 238 ? 125.109 120.114 106.660 1.00 24.97  ? 238 ILE A O   1 
ATOM   1766  C CB  . ILE A 1 238 ? 127.134 119.700 108.989 1.00 24.97  ? 238 ILE A CB  1 
ATOM   1767  C CG1 . ILE A 1 238 ? 128.477 119.405 109.650 1.00 24.97  ? 238 ILE A CG1 1 
ATOM   1768  C CG2 . ILE A 1 238 ? 126.012 119.051 109.785 1.00 24.97  ? 238 ILE A CG2 1 
ATOM   1769  C CD1 . ILE A 1 238 ? 128.687 120.120 110.939 1.00 24.97  ? 238 ILE A CD1 1 
ATOM   1770  N N   . VAL A 1 239 ? 125.216 117.868 106.876 1.00 27.52  ? 239 VAL A N   1 
ATOM   1771  C CA  . VAL A 1 239 ? 123.885 117.593 106.343 1.00 27.52  ? 239 VAL A CA  1 
ATOM   1772  C C   . VAL A 1 239 ? 123.044 116.970 107.452 1.00 27.52  ? 239 VAL A C   1 
ATOM   1773  O O   . VAL A 1 239 ? 123.372 115.887 107.954 1.00 27.52  ? 239 VAL A O   1 
ATOM   1774  C CB  . VAL A 1 239 ? 123.943 116.673 105.113 1.00 27.52  ? 239 VAL A CB  1 
ATOM   1775  C CG1 . VAL A 1 239 ? 122.551 116.451 104.550 1.00 27.52  ? 239 VAL A CG1 1 
ATOM   1776  C CG2 . VAL A 1 239 ? 124.862 117.261 104.053 1.00 27.52  ? 239 VAL A CG2 1 
ATOM   1777  N N   . LYS A 1 240 ? 121.961 117.653 107.826 1.00 31.82  ? 240 LYS A N   1 
ATOM   1778  C CA  . LYS A 1 240 ? 121.052 117.205 108.870 1.00 31.82  ? 240 LYS A CA  1 
ATOM   1779  C C   . LYS A 1 240 ? 120.073 116.162 108.335 1.00 31.82  ? 240 LYS A C   1 
ATOM   1780  O O   . LYS A 1 240 ? 119.850 116.069 107.127 1.00 31.82  ? 240 LYS A O   1 
ATOM   1781  C CB  . LYS A 1 240 ? 120.282 118.393 109.440 1.00 31.82  ? 240 LYS A CB  1 
ATOM   1782  C CG  . LYS A 1 240 ? 121.085 119.672 109.558 1.00 31.82  ? 240 LYS A CG  1 
ATOM   1783  C CD  . LYS A 1 240 ? 121.846 119.727 110.867 1.00 31.82  ? 240 LYS A CD  1 
ATOM   1784  C CE  . LYS A 1 240 ? 120.905 119.696 112.057 1.00 31.82  ? 240 LYS A CE  1 
ATOM   1785  N NZ  . LYS A 1 240 ? 121.550 119.095 113.254 1.00 31.82  ? 240 LYS A NZ  1 
ATOM   1786  N N   . PRO A 1 241 ? 119.481 115.356 109.219 1.00 32.53  ? 241 PRO A N   1 
ATOM   1787  C CA  . PRO A 1 241 ? 118.495 114.362 108.769 1.00 32.53  ? 241 PRO A CA  1 
ATOM   1788  C C   . PRO A 1 241 ? 117.330 115.016 108.039 1.00 32.53  ? 241 PRO A C   1 
ATOM   1789  O O   . PRO A 1 241 ? 116.779 116.024 108.485 1.00 32.53  ? 241 PRO A O   1 
ATOM   1790  C CB  . PRO A 1 241 ? 118.043 113.698 110.074 1.00 32.53  ? 241 PRO A CB  1 
ATOM   1791  C CG  . PRO A 1 241 ? 119.170 113.900 111.008 1.00 32.53  ? 241 PRO A CG  1 
ATOM   1792  C CD  . PRO A 1 241 ? 119.770 115.224 110.657 1.00 32.53  ? 241 PRO A CD  1 
ATOM   1793  N N   . GLY A 1 242 ? 116.954 114.423 106.909 1.00 32.35  ? 242 GLY A N   1 
ATOM   1794  C CA  . GLY A 1 242 ? 115.902 114.953 106.074 1.00 32.35  ? 242 GLY A CA  1 
ATOM   1795  C C   . GLY A 1 242 ? 116.347 115.960 105.036 1.00 32.35  ? 242 GLY A C   1 
ATOM   1796  O O   . GLY A 1 242 ? 115.523 116.384 104.218 1.00 32.35  ? 242 GLY A O   1 
ATOM   1797  N N   . ASP A 1 243 ? 117.617 116.356 105.037 1.00 32.66  ? 243 ASP A N   1 
ATOM   1798  C CA  . ASP A 1 243 ? 118.143 117.298 104.066 1.00 32.66  ? 243 ASP A CA  1 
ATOM   1799  C C   . ASP A 1 243 ? 118.829 116.545 102.928 1.00 32.66  ? 243 ASP A C   1 
ATOM   1800  O O   . ASP A 1 243 ? 118.843 115.314 102.878 1.00 32.66  ? 243 ASP A O   1 
ATOM   1801  C CB  . ASP A 1 243 ? 119.099 118.283 104.740 1.00 32.66  ? 243 ASP A CB  1 
ATOM   1802  C CG  . ASP A 1 243 ? 119.023 119.673 104.141 1.00 32.66  ? 243 ASP A CG  1 
ATOM   1803  O OD1 . ASP A 1 243 ? 118.951 119.788 102.902 1.00 32.66  ? 243 ASP A OD1 1 
ATOM   1804  O OD2 . ASP A 1 243 ? 119.043 120.654 104.911 1.00 32.66  ? 243 ASP A OD2 1 
ATOM   1805  N N   . VAL A 1 244 ? 119.407 117.303 102.000 1.00 30.93  ? 244 VAL A N   1 
ATOM   1806  C CA  . VAL A 1 244 ? 120.013 116.745 100.799 1.00 30.93  ? 244 VAL A CA  1 
ATOM   1807  C C   . VAL A 1 244 ? 121.230 117.581 100.426 1.00 30.93  ? 244 VAL A C   1 
ATOM   1808  O O   . VAL A 1 244 ? 121.260 118.796 100.637 1.00 30.93  ? 244 VAL A O   1 
ATOM   1809  C CB  . VAL A 1 244 ? 118.987 116.684 99.640  1.00 30.93  ? 244 VAL A CB  1 
ATOM   1810  C CG1 . VAL A 1 244 ? 118.464 118.071 99.313  1.00 30.93  ? 244 VAL A CG1 1 
ATOM   1811  C CG2 . VAL A 1 244 ? 119.585 116.028 98.413  1.00 30.93  ? 244 VAL A CG2 1 
ATOM   1812  N N   . LEU A 1 245 ? 122.248 116.919 99.885  1.00 27.51  ? 245 LEU A N   1 
ATOM   1813  C CA  . LEU A 1 245 ? 123.469 117.569 99.430  1.00 27.51  ? 245 LEU A CA  1 
ATOM   1814  C C   . LEU A 1 245 ? 123.496 117.581 97.909  1.00 27.51  ? 245 LEU A C   1 
ATOM   1815  O O   . LEU A 1 245 ? 123.237 116.554 97.275  1.00 27.51  ? 245 LEU A O   1 
ATOM   1816  C CB  . LEU A 1 245 ? 124.703 116.844 99.973  1.00 27.51  ? 245 LEU A CB  1 
ATOM   1817  C CG  . LEU A 1 245 ? 126.068 117.392 99.559  1.00 27.51  ? 245 LEU A CG  1 
ATOM   1818  C CD1 . LEU A 1 245 ? 126.480 118.516 100.488 1.00 27.51  ? 245 LEU A CD1 1 
ATOM   1819  C CD2 . LEU A 1 245 ? 127.110 116.292 99.551  1.00 27.51  ? 245 LEU A CD2 1 
ATOM   1820  N N   . VAL A 1 246 ? 123.807 118.737 97.325  1.00 27.06  ? 246 VAL A N   1 
ATOM   1821  C CA  . VAL A 1 246 ? 123.958 118.874 95.882  1.00 27.06  ? 246 VAL A CA  1 
ATOM   1822  C C   . VAL A 1 246 ? 125.350 119.419 95.590  1.00 27.06  ? 246 VAL A C   1 
ATOM   1823  O O   . VAL A 1 246 ? 125.775 120.415 96.191  1.00 27.06  ? 246 VAL A O   1 
ATOM   1824  C CB  . VAL A 1 246 ? 122.873 119.778 95.267  1.00 27.06  ? 246 VAL A CB  1 
ATOM   1825  C CG1 . VAL A 1 246 ? 123.160 120.019 93.797  1.00 27.06  ? 246 VAL A CG1 1 
ATOM   1826  C CG2 . VAL A 1 246 ? 121.502 119.146 95.431  1.00 27.06  ? 246 VAL A CG2 1 
ATOM   1827  N N   . ILE A 1 247 ? 126.054 118.757 94.675  1.00 26.89  ? 247 ILE A N   1 
ATOM   1828  C CA  . ILE A 1 247 ? 127.377 119.166 94.219  1.00 26.89  ? 247 ILE A CA  1 
ATOM   1829  C C   . ILE A 1 247 ? 127.280 119.486 92.734  1.00 26.89  ? 247 ILE A C   1 
ATOM   1830  O O   . ILE A 1 247 ? 126.865 118.636 91.934  1.00 26.89  ? 247 ILE A O   1 
ATOM   1831  C CB  . ILE A 1 247 ? 128.437 118.083 94.479  1.00 26.89  ? 247 ILE A CB  1 
ATOM   1832  C CG1 . ILE A 1 247 ? 128.480 117.719 95.965  1.00 26.89  ? 247 ILE A CG1 1 
ATOM   1833  C CG2 . ILE A 1 247 ? 129.803 118.547 94.003  1.00 26.89  ? 247 ILE A CG2 1 
ATOM   1834  C CD1 . ILE A 1 247 ? 129.200 116.427 96.256  1.00 26.89  ? 247 ILE A CD1 1 
ATOM   1835  N N   . ASN A 1 248 ? 127.665 120.708 92.370  1.00 28.54  ? 248 ASN A N   1 
ATOM   1836  C CA  . ASN A 1 248 ? 127.603 121.199 90.999  1.00 28.54  ? 248 ASN A CA  1 
ATOM   1837  C C   . ASN A 1 248 ? 128.957 121.800 90.655  1.00 28.54  ? 248 ASN A C   1 
ATOM   1838  O O   . ASN A 1 248 ? 129.386 122.769 91.288  1.00 28.54  ? 248 ASN A O   1 
ATOM   1839  C CB  . ASN A 1 248 ? 126.486 122.238 90.845  1.00 28.54  ? 248 ASN A CB  1 
ATOM   1840  C CG  . ASN A 1 248 ? 126.335 122.733 89.423  1.00 28.54  ? 248 ASN A CG  1 
ATOM   1841  O OD1 . ASN A 1 248 ? 126.933 123.734 89.039  1.00 28.54  ? 248 ASN A OD1 1 
ATOM   1842  N ND2 . ASN A 1 248 ? 125.517 122.046 88.639  1.00 28.54  ? 248 ASN A ND2 1 
ATOM   1843  N N   . SER A 1 249 ? 129.628 121.241 89.656  1.00 29.68  ? 249 SER A N   1 
ATOM   1844  C CA  . SER A 1 249 ? 131.005 121.637 89.398  1.00 29.68  ? 249 SER A CA  1 
ATOM   1845  C C   . SER A 1 249 ? 131.294 121.736 87.911  1.00 29.68  ? 249 SER A C   1 
ATOM   1846  O O   . SER A 1 249 ? 130.860 120.894 87.120  1.00 29.68  ? 249 SER A O   1 
ATOM   1847  C CB  . SER A 1 249 ? 131.998 120.663 90.039  1.00 29.68  ? 249 SER A CB  1 
ATOM   1848  O OG  . SER A 1 249 ? 133.327 121.005 89.689  1.00 29.68  ? 249 SER A OG  1 
ATOM   1849  N N   . ASN A 1 250 ? 132.058 122.766 87.550  1.00 31.83  ? 250 ASN A N   1 
ATOM   1850  C CA  . ASN A 1 250 ? 132.544 122.951 86.192  1.00 31.83  ? 250 ASN A CA  1 
ATOM   1851  C C   . ASN A 1 250 ? 133.998 122.529 86.017  1.00 31.83  ? 250 ASN A C   1 
ATOM   1852  O O   . ASN A 1 250 ? 134.457 122.400 84.878  1.00 31.83  ? 250 ASN A O   1 
ATOM   1853  C CB  . ASN A 1 250 ? 132.386 124.418 85.776  1.00 31.83  ? 250 ASN A CB  1 
ATOM   1854  C CG  . ASN A 1 250 ? 132.161 124.572 84.299  1.00 31.83  ? 250 ASN A CG  1 
ATOM   1855  O OD1 . ASN A 1 250 ? 131.705 123.644 83.635  1.00 31.83  ? 250 ASN A OD1 1 
ATOM   1856  N ND2 . ASN A 1 250 ? 132.472 125.748 83.770  1.00 31.83  ? 250 ASN A ND2 1 
ATOM   1857  N N   . GLY A 1 251 ? 134.727 122.327 87.109  1.00 28.50  ? 251 GLY A N   1 
ATOM   1858  C CA  . GLY A 1 251 ? 136.117 121.923 87.062  1.00 28.50  ? 251 GLY A CA  1 
ATOM   1859  C C   . GLY A 1 251 ? 136.794 122.137 88.399  1.00 28.50  ? 251 GLY A C   1 
ATOM   1860  O O   . GLY A 1 251 ? 136.247 122.828 89.262  1.00 28.50  ? 251 GLY A O   1 
ATOM   1861  N N   . ASN A 1 252 ? 137.973 121.539 88.583  1.00 27.05  ? 252 ASN A N   1 
ATOM   1862  C CA  . ASN A 1 252 ? 138.817 121.709 89.766  1.00 27.05  ? 252 ASN A CA  1 
ATOM   1863  C C   . ASN A 1 252 ? 138.213 121.113 91.035  1.00 27.05  ? 252 ASN A C   1 
ATOM   1864  O O   . ASN A 1 252 ? 138.550 121.550 92.137  1.00 27.05  ? 252 ASN A O   1 
ATOM   1865  C CB  . ASN A 1 252 ? 139.154 123.188 90.012  1.00 27.05  ? 252 ASN A CB  1 
ATOM   1866  C CG  . ASN A 1 252 ? 139.776 123.862 88.803  1.00 27.05  ? 252 ASN A CG  1 
ATOM   1867  O OD1 . ASN A 1 252 ? 139.117 124.077 87.789  1.00 27.05  ? 252 ASN A OD1 1 
ATOM   1868  N ND2 . ASN A 1 252 ? 141.051 124.208 88.912  1.00 27.05  ? 252 ASN A ND2 1 
ATOM   1869  N N   . LEU A 1 253 ? 137.339 120.116 90.925  1.00 23.90  ? 253 LEU A N   1 
ATOM   1870  C CA  . LEU A 1 253 ? 136.683 119.539 92.093  1.00 23.90  ? 253 LEU A CA  1 
ATOM   1871  C C   . LEU A 1 253 ? 137.469 118.352 92.637  1.00 23.90  ? 253 LEU A C   1 
ATOM   1872  O O   . LEU A 1 253 ? 137.847 117.450 91.884  1.00 23.90  ? 253 LEU A O   1 
ATOM   1873  C CB  . LEU A 1 253 ? 135.256 119.103 91.756  1.00 23.90  ? 253 LEU A CB  1 
ATOM   1874  C CG  . LEU A 1 253 ? 134.593 118.150 92.758  1.00 23.90  ? 253 LEU A CG  1 
ATOM   1875  C CD1 . LEU A 1 253 ? 134.216 118.872 94.043  1.00 23.90  ? 253 LEU A CD1 1 
ATOM   1876  C CD2 . LEU A 1 253 ? 133.384 117.462 92.145  1.00 23.90  ? 253 LEU A CD2 1 
ATOM   1877  N N   . ILE A 1 254 ? 137.703 118.357 93.946  1.00 22.62  ? 254 ILE A N   1 
ATOM   1878  C CA  . ILE A 1 254 ? 138.220 117.202 94.673  1.00 22.62  ? 254 ILE A CA  1 
ATOM   1879  C C   . ILE A 1 254 ? 137.030 116.605 95.416  1.00 22.62  ? 254 ILE A C   1 
ATOM   1880  O O   . ILE A 1 254 ? 136.609 117.120 96.453  1.00 22.62  ? 254 ILE A O   1 
ATOM   1881  C CB  . ILE A 1 254 ? 139.355 117.587 95.628  1.00 22.62  ? 254 ILE A CB  1 
ATOM   1882  C CG1 . ILE A 1 254 ? 140.382 118.476 94.920  1.00 22.62  ? 254 ILE A CG1 1 
ATOM   1883  C CG2 . ILE A 1 254 ? 140.022 116.344 96.201  1.00 22.62  ? 254 ILE A CG2 1 
ATOM   1884  C CD1 . ILE A 1 254 ? 141.188 117.762 93.860  1.00 22.62  ? 254 ILE A CD1 1 
ATOM   1885  N N   . ALA A 1 255 ? 136.481 115.516 94.886  1.00 22.48  ? 255 ALA A N   1 
ATOM   1886  C CA  . ALA A 1 255 ? 135.205 114.996 95.347  1.00 22.48  ? 255 ALA A CA  1 
ATOM   1887  C C   . ALA A 1 255 ? 135.353 114.179 96.630  1.00 22.48  ? 255 ALA A C   1 
ATOM   1888  O O   . ALA A 1 255 ? 136.403 113.584 96.881  1.00 22.48  ? 255 ALA A O   1 
ATOM   1889  C CB  . ALA A 1 255 ? 134.570 114.133 94.265  1.00 22.48  ? 255 ALA A CB  1 
ATOM   1890  N N   . PRO A 1 256 ? 134.315 114.142 97.458  1.00 22.56  ? 256 PRO A N   1 
ATOM   1891  C CA  . PRO A 1 256 ? 134.300 113.210 98.586  1.00 22.56  ? 256 PRO A CA  1 
ATOM   1892  C C   . PRO A 1 256 ? 133.975 111.795 98.131  1.00 22.56  ? 256 PRO A C   1 
ATOM   1893  O O   . PRO A 1 256 ? 133.398 111.566 97.068  1.00 22.56  ? 256 PRO A O   1 
ATOM   1894  C CB  . PRO A 1 256 ? 133.194 113.767 99.487  1.00 22.56  ? 256 PRO A CB  1 
ATOM   1895  C CG  . PRO A 1 256 ? 132.263 114.433 98.548  1.00 22.56  ? 256 PRO A CG  1 
ATOM   1896  C CD  . PRO A 1 256 ? 133.090 114.959 97.403  1.00 22.56  ? 256 PRO A CD  1 
ATOM   1897  N N   . ARG A 1 257 ? 134.366 110.836 98.964  1.00 22.95  ? 257 ARG A N   1 
ATOM   1898  C CA  . ARG A 1 257 ? 134.069 109.432 98.727  1.00 22.95  ? 257 ARG A CA  1 
ATOM   1899  C C   . ARG A 1 257 ? 132.994 108.897 99.659  1.00 22.95  ? 257 ARG A C   1 
ATOM   1900  O O   . ARG A 1 257 ? 132.576 107.746 99.507  1.00 22.95  ? 257 ARG A O   1 
ATOM   1901  C CB  . ARG A 1 257 ? 135.341 108.590 98.872  1.00 22.95  ? 257 ARG A CB  1 
ATOM   1902  C CG  . ARG A 1 257 ? 136.355 108.794 97.767  1.00 22.95  ? 257 ARG A CG  1 
ATOM   1903  C CD  . ARG A 1 257 ? 137.487 107.797 97.893  1.00 22.95  ? 257 ARG A CD  1 
ATOM   1904  N NE  . ARG A 1 257 ? 138.591 108.089 96.990  1.00 22.95  ? 257 ARG A NE  1 
ATOM   1905  C CZ  . ARG A 1 257 ? 138.688 107.634 95.749  1.00 22.95  ? 257 ARG A CZ  1 
ATOM   1906  N NH1 . ARG A 1 257 ? 137.749 106.871 95.217  1.00 22.95  ? 257 ARG A NH1 1 
ATOM   1907  N NH2 . ARG A 1 257 ? 139.756 107.949 95.024  1.00 22.95  ? 257 ARG A NH2 1 
ATOM   1908  N N   . GLY A 1 258 ? 132.535 109.706 100.607 1.00 23.47  ? 258 GLY A N   1 
ATOM   1909  C CA  . GLY A 1 258 ? 131.585 109.256 101.606 1.00 23.47  ? 258 GLY A CA  1 
ATOM   1910  C C   . GLY A 1 258 ? 131.433 110.319 102.676 1.00 23.47  ? 258 GLY A C   1 
ATOM   1911  O O   . GLY A 1 258 ? 131.750 111.486 102.448 1.00 23.47  ? 258 GLY A O   1 
ATOM   1912  N N   . PHE A 1 259 ? 130.956 109.903 103.845 1.00 23.22  ? 259 PHE A N   1 
ATOM   1913  C CA  . PHE A 1 259 ? 130.737 110.846 104.935 1.00 23.22  ? 259 PHE A CA  1 
ATOM   1914  C C   . PHE A 1 259 ? 131.321 110.325 106.243 1.00 23.22  ? 259 PHE A C   1 
ATOM   1915  O O   . PHE A 1 259 ? 131.533 109.126 106.429 1.00 23.22  ? 259 PHE A O   1 
ATOM   1916  C CB  . PHE A 1 259 ? 129.239 111.182 105.111 1.00 23.22  ? 259 PHE A CB  1 
ATOM   1917  C CG  . PHE A 1 259 ? 128.393 110.025 105.576 1.00 23.22  ? 259 PHE A CG  1 
ATOM   1918  C CD1 . PHE A 1 259 ? 128.221 109.772 106.927 1.00 23.22  ? 259 PHE A CD1 1 
ATOM   1919  C CD2 . PHE A 1 259 ? 127.758 109.203 104.663 1.00 23.22  ? 259 PHE A CD2 1 
ATOM   1920  C CE1 . PHE A 1 259 ? 127.446 108.717 107.354 1.00 23.22  ? 259 PHE A CE1 1 
ATOM   1921  C CE2 . PHE A 1 259 ? 126.979 108.145 105.086 1.00 23.22  ? 259 PHE A CE2 1 
ATOM   1922  C CZ  . PHE A 1 259 ? 126.822 107.904 106.432 1.00 23.22  ? 259 PHE A CZ  1 
ATOM   1923  N N   . PHE A 1 260 ? 131.588 111.265 107.147 1.00 24.46  ? 260 PHE A N   1 
ATOM   1924  C CA  . PHE A 1 260 ? 132.020 110.978 108.507 1.00 24.46  ? 260 PHE A CA  1 
ATOM   1925  C C   . PHE A 1 260 ? 130.842 111.114 109.463 1.00 24.46  ? 260 PHE A C   1 
ATOM   1926  O O   . PHE A 1 260 ? 130.050 112.054 109.358 1.00 24.46  ? 260 PHE A O   1 
ATOM   1927  C CB  . PHE A 1 260 ? 133.133 111.931 108.953 1.00 24.46  ? 260 PHE A CB  1 
ATOM   1928  C CG  . PHE A 1 260 ? 134.458 111.690 108.290 1.00 24.46  ? 260 PHE A CG  1 
ATOM   1929  C CD1 . PHE A 1 260 ? 135.345 110.758 108.802 1.00 24.46  ? 260 PHE A CD1 1 
ATOM   1930  C CD2 . PHE A 1 260 ? 134.828 112.413 107.169 1.00 24.46  ? 260 PHE A CD2 1 
ATOM   1931  C CE1 . PHE A 1 260 ? 136.567 110.543 108.201 1.00 24.46  ? 260 PHE A CE1 1 
ATOM   1932  C CE2 . PHE A 1 260 ? 136.049 112.200 106.564 1.00 24.46  ? 260 PHE A CE2 1 
ATOM   1933  C CZ  . PHE A 1 260 ? 136.920 111.265 107.082 1.00 24.46  ? 260 PHE A CZ  1 
ATOM   1934  N N   . LYS A 1 261 ? 130.728 110.173 110.394 1.00 30.58  ? 261 LYS A N   1 
ATOM   1935  C CA  . LYS A 1 261 ? 129.777 110.331 111.485 1.00 30.58  ? 261 LYS A CA  1 
ATOM   1936  C C   . LYS A 1 261 ? 130.290 111.372 112.469 1.00 30.58  ? 261 LYS A C   1 
ATOM   1937  O O   . LYS A 1 261 ? 131.478 111.409 112.794 1.00 30.58  ? 261 LYS A O   1 
ATOM   1938  C CB  . LYS A 1 261 ? 129.553 109.001 112.200 1.00 30.58  ? 261 LYS A CB  1 
ATOM   1939  C CG  . LYS A 1 261 ? 128.766 107.985 111.403 1.00 30.58  ? 261 LYS A CG  1 
ATOM   1940  C CD  . LYS A 1 261 ? 127.577 107.480 112.198 1.00 30.58  ? 261 LYS A CD  1 
ATOM   1941  C CE  . LYS A 1 261 ? 127.409 105.981 112.044 1.00 30.58  ? 261 LYS A CE  1 
ATOM   1942  N NZ  . LYS A 1 261 ? 127.515 105.559 110.624 1.00 30.58  ? 261 LYS A NZ  1 
ATOM   1943  N N   . ILE A 1 262 ? 129.391 112.227 112.943 1.00 32.00  ? 262 ILE A N   1 
ATOM   1944  C CA  . ILE A 1 262 ? 129.733 113.271 113.900 1.00 32.00  ? 262 ILE A CA  1 
ATOM   1945  C C   . ILE A 1 262 ? 128.880 113.072 115.146 1.00 32.00  ? 262 ILE A C   1 
ATOM   1946  O O   . ILE A 1 262 ? 127.664 112.871 115.050 1.00 32.00  ? 262 ILE A O   1 
ATOM   1947  C CB  . ILE A 1 262 ? 129.561 114.680 113.298 1.00 32.00  ? 262 ILE A CB  1 
ATOM   1948  C CG1 . ILE A 1 262 ? 130.067 115.749 114.271 1.00 32.00  ? 262 ILE A CG1 1 
ATOM   1949  C CG2 . ILE A 1 262 ? 128.128 114.936 112.859 1.00 32.00  ? 262 ILE A CG2 1 
ATOM   1950  C CD1 . ILE A 1 262 ? 130.049 117.149 113.702 1.00 32.00  ? 262 ILE A CD1 1 
ATOM   1951  N N   . ARG A 1 263 ? 129.524 113.090 116.308 1.00 34.75  ? 263 ARG A N   1 
ATOM   1952  C CA  . ARG A 1 263 ? 128.879 112.768 117.569 1.00 34.75  ? 263 ARG A CA  1 
ATOM   1953  C C   . ARG A 1 263 ? 129.091 113.902 118.559 1.00 34.75  ? 263 ARG A C   1 
ATOM   1954  O O   . ARG A 1 263 ? 129.898 114.809 118.344 1.00 34.75  ? 263 ARG A O   1 
ATOM   1955  C CB  . ARG A 1 263 ? 129.413 111.449 118.145 1.00 34.75  ? 263 ARG A CB  1 
ATOM   1956  C CG  . ARG A 1 263 ? 129.197 110.260 117.231 1.00 34.75  ? 263 ARG A CG  1 
ATOM   1957  C CD  . ARG A 1 263 ? 129.382 108.940 117.956 1.00 34.75  ? 263 ARG A CD  1 
ATOM   1958  N NE  . ARG A 1 263 ? 130.184 108.012 117.170 1.00 34.75  ? 263 ARG A NE  1 
ATOM   1959  C CZ  . ARG A 1 263 ? 129.691 107.169 116.272 1.00 34.75  ? 263 ARG A CZ  1 
ATOM   1960  N NH1 . ARG A 1 263 ? 128.392 107.100 116.029 1.00 34.75  ? 263 ARG A NH1 1 
ATOM   1961  N NH2 . ARG A 1 263 ? 130.522 106.379 115.598 1.00 34.75  ? 263 ARG A NH2 1 
ATOM   1962  N N   . THR A 1 264 ? 128.336 113.844 119.650 1.00 36.86  ? 264 THR A N   1 
ATOM   1963  C CA  . THR A 1 264 ? 128.479 114.758 120.773 1.00 36.86  ? 264 THR A CA  1 
ATOM   1964  C C   . THR A 1 264 ? 129.038 113.987 121.959 1.00 36.86  ? 264 THR A C   1 
ATOM   1965  O O   . THR A 1 264 ? 128.538 112.907 122.291 1.00 36.86  ? 264 THR A O   1 
ATOM   1966  C CB  . THR A 1 264 ? 127.138 115.399 121.139 1.00 36.86  ? 264 THR A CB  1 
ATOM   1967  O OG1 . THR A 1 264 ? 126.605 116.085 120.000 1.00 36.86  ? 264 THR A OG1 1 
ATOM   1968  C CG2 . THR A 1 264 ? 127.314 116.386 122.280 1.00 36.86  ? 264 THR A CG2 1 
ATOM   1969  N N   . GLY A 1 265 ? 130.068 114.532 122.585 1.00 34.86  ? 265 GLY A N   1 
ATOM   1970  C CA  . GLY A 1 265 ? 130.685 113.849 123.698 1.00 34.86  ? 265 GLY A CA  1 
ATOM   1971  C C   . GLY A 1 265 ? 131.704 114.715 124.396 1.00 34.86  ? 265 GLY A C   1 
ATOM   1972  O O   . GLY A 1 265 ? 131.710 115.938 124.251 1.00 34.86  ? 265 GLY A O   1 
ATOM   1973  N N   . ARG A 1 266 ? 132.578 114.057 125.155 1.00 33.87  ? 266 ARG A N   1 
ATOM   1974  C CA  . ARG A 1 266 ? 133.555 114.730 126.001 1.00 33.87  ? 266 ARG A CA  1 
ATOM   1975  C C   . ARG A 1 266 ? 134.992 114.499 125.537 1.00 33.87  ? 266 ARG A C   1 
ATOM   1976  O O   . ARG A 1 266 ? 135.917 114.508 126.350 1.00 33.87  ? 266 ARG A O   1 
ATOM   1977  C CB  . ARG A 1 266 ? 133.380 114.280 127.450 1.00 33.87  ? 266 ARG A CB  1 
ATOM   1978  C CG  . ARG A 1 266 ? 133.450 112.773 127.640 1.00 33.87  ? 266 ARG A CG  1 
ATOM   1979  C CD  . ARG A 1 266 ? 134.229 112.420 128.890 1.00 33.87  ? 266 ARG A CD  1 
ATOM   1980  N NE  . ARG A 1 266 ? 134.538 110.999 128.979 1.00 33.87  ? 266 ARG A NE  1 
ATOM   1981  C CZ  . ARG A 1 266 ? 135.738 110.512 129.264 1.00 33.87  ? 266 ARG A CZ  1 
ATOM   1982  N NH1 . ARG A 1 266 ? 136.774 111.307 129.474 1.00 33.87  ? 266 ARG A NH1 1 
ATOM   1983  N NH2 . ARG A 1 266 ? 135.901 109.195 129.346 1.00 33.87  ? 266 ARG A NH2 1 
ATOM   1984  N N   . SER A 1 267 ? 135.194 114.298 124.238 1.00 28.21  ? 267 SER A N   1 
ATOM   1985  C CA  . SER A 1 267 ? 136.521 114.069 123.684 1.00 28.21  ? 267 SER A CA  1 
ATOM   1986  C C   . SER A 1 267 ? 137.230 115.394 123.409 1.00 28.21  ? 267 SER A C   1 
ATOM   1987  O O   . SER A 1 267 ? 136.601 116.441 123.250 1.00 28.21  ? 267 SER A O   1 
ATOM   1988  C CB  . SER A 1 267 ? 136.431 113.245 122.400 1.00 28.21  ? 267 SER A CB  1 
ATOM   1989  O OG  . SER A 1 267 ? 136.000 111.924 122.665 1.00 28.21  ? 267 SER A OG  1 
ATOM   1990  N N   . SER A 1 268 ? 138.558 115.333 123.349 1.00 26.90  ? 268 SER A N   1 
ATOM   1991  C CA  . SER A 1 268 ? 139.374 116.528 123.162 1.00 26.90  ? 268 SER A CA  1 
ATOM   1992  C C   . SER A 1 268 ? 140.732 116.123 122.597 1.00 26.90  ? 268 SER A C   1 
ATOM   1993  O O   . SER A 1 268 ? 141.001 114.944 122.354 1.00 26.90  ? 268 SER A O   1 
ATOM   1994  C CB  . SER A 1 268 ? 139.519 117.301 124.475 1.00 26.90  ? 268 SER A CB  1 
ATOM   1995  O OG  . SER A 1 268 ? 140.081 118.581 124.252 1.00 26.90  ? 268 SER A OG  1 
ATOM   1996  N N   . ILE A 1 269 ? 141.593 117.123 122.397 1.00 24.83  ? 269 ILE A N   1 
ATOM   1997  C CA  . ILE A 1 269 ? 142.918 116.938 121.816 1.00 24.83  ? 269 ILE A CA  1 
ATOM   1998  C C   . ILE A 1 269 ? 143.931 117.721 122.644 1.00 24.83  ? 269 ILE A C   1 
ATOM   1999  O O   . ILE A 1 269 ? 143.604 118.745 123.250 1.00 24.83  ? 269 ILE A O   1 
ATOM   2000  C CB  . ILE A 1 269 ? 142.947 117.376 120.328 1.00 24.83  ? 269 ILE A CB  1 
ATOM   2001  C CG1 . ILE A 1 269 ? 144.291 117.043 119.676 1.00 24.83  ? 269 ILE A CG1 1 
ATOM   2002  C CG2 . ILE A 1 269 ? 142.633 118.859 120.186 1.00 24.83  ? 269 ILE A CG2 1 
ATOM   2003  C CD1 . ILE A 1 269 ? 144.252 117.056 118.167 1.00 24.83  ? 269 ILE A CD1 1 
ATOM   2004  N N   . MET A 1 270 ? 145.171 117.231 122.673 1.00 27.26  ? 270 MET A N   1 
ATOM   2005  C CA  . MET A 1 270 ? 146.232 117.834 123.469 1.00 27.26  ? 270 MET A CA  1 
ATOM   2006  C C   . MET A 1 270 ? 147.570 117.718 122.751 1.00 27.26  ? 270 MET A C   1 
ATOM   2007  O O   . MET A 1 270 ? 147.847 116.709 122.099 1.00 27.26  ? 270 MET A O   1 
ATOM   2008  C CB  . MET A 1 270 ? 146.341 117.167 124.846 1.00 27.26  ? 270 MET A CB  1 
ATOM   2009  C CG  . MET A 1 270 ? 147.050 118.001 125.894 1.00 27.26  ? 270 MET A CG  1 
ATOM   2010  S SD  . MET A 1 270 ? 147.081 117.193 127.506 1.00 27.26  ? 270 MET A SD  1 
ATOM   2011  C CE  . MET A 1 270 ? 145.785 118.083 128.355 1.00 27.26  ? 270 MET A CE  1 
ATOM   2012  N N   . ARG A 1 271 ? 148.401 118.747 122.892 1.00 26.84  ? 271 ARG A N   1 
ATOM   2013  C CA  . ARG A 1 271 ? 149.773 118.731 122.397 1.00 26.84  ? 271 ARG A CA  1 
ATOM   2014  C C   . ARG A 1 271 ? 150.703 118.378 123.552 1.00 26.84  ? 271 ARG A C   1 
ATOM   2015  O O   . ARG A 1 271 ? 150.715 119.071 124.573 1.00 26.84  ? 271 ARG A O   1 
ATOM   2016  C CB  . ARG A 1 271 ? 150.159 120.083 121.795 1.00 26.84  ? 271 ARG A CB  1 
ATOM   2017  C CG  . ARG A 1 271 ? 149.312 120.522 120.613 1.00 26.84  ? 271 ARG A CG  1 
ATOM   2018  C CD  . ARG A 1 271 ? 149.848 121.804 119.995 1.00 26.84  ? 271 ARG A CD  1 
ATOM   2019  N NE  . ARG A 1 271 ? 149.007 122.293 118.909 1.00 26.84  ? 271 ARG A NE  1 
ATOM   2020  C CZ  . ARG A 1 271 ? 148.039 123.189 119.051 1.00 26.84  ? 271 ARG A CZ  1 
ATOM   2021  N NH1 . ARG A 1 271 ? 147.769 123.734 120.225 1.00 26.84  ? 271 ARG A NH1 1 
ATOM   2022  N NH2 . ARG A 1 271 ? 147.325 123.547 117.989 1.00 26.84  ? 271 ARG A NH2 1 
ATOM   2023  N N   . SER A 1 272 ? 151.478 117.308 123.392 1.00 30.16  ? 272 SER A N   1 
ATOM   2024  C CA  . SER A 1 272 ? 152.366 116.860 124.457 1.00 30.16  ? 272 SER A CA  1 
ATOM   2025  C C   . SER A 1 272 ? 153.406 115.906 123.890 1.00 30.16  ? 272 SER A C   1 
ATOM   2026  O O   . SER A 1 272 ? 153.156 115.210 122.904 1.00 30.16  ? 272 SER A O   1 
ATOM   2027  C CB  . SER A 1 272 ? 151.584 116.176 125.585 1.00 30.16  ? 272 SER A CB  1 
ATOM   2028  O OG  . SER A 1 272 ? 152.455 115.627 126.556 1.00 30.16  ? 272 SER A OG  1 
ATOM   2029  N N   . ASP A 1 273 ? 154.573 115.877 124.533 1.00 34.09  ? 273 ASP A N   1 
ATOM   2030  C CA  . ASP A 1 273 ? 155.636 114.942 124.193 1.00 34.09  ? 273 ASP A CA  1 
ATOM   2031  C C   . ASP A 1 273 ? 155.900 113.913 125.285 1.00 34.09  ? 273 ASP A C   1 
ATOM   2032  O O   . ASP A 1 273 ? 156.839 113.123 125.155 1.00 34.09  ? 273 ASP A O   1 
ATOM   2033  C CB  . ASP A 1 273 ? 156.932 115.701 123.881 1.00 34.09  ? 273 ASP A CB  1 
ATOM   2034  C CG  . ASP A 1 273 ? 156.915 116.348 122.509 1.00 34.09  ? 273 ASP A CG  1 
ATOM   2035  O OD1 . ASP A 1 273 ? 156.433 115.711 121.550 1.00 34.09  ? 273 ASP A OD1 1 
ATOM   2036  O OD2 . ASP A 1 273 ? 157.383 117.498 122.390 1.00 34.09  ? 273 ASP A OD2 1 
ATOM   2037  N N   . ALA A 1 274 ? 155.105 113.900 126.350 1.00 33.57  ? 274 ALA A N   1 
ATOM   2038  C CA  . ALA A 1 274 ? 155.322 112.951 127.433 1.00 33.57  ? 274 ALA A CA  1 
ATOM   2039  C C   . ALA A 1 274 ? 154.951 111.537 126.991 1.00 33.57  ? 274 ALA A C   1 
ATOM   2040  O O   . ALA A 1 274 ? 153.976 111.349 126.259 1.00 33.57  ? 274 ALA A O   1 
ATOM   2041  C CB  . ALA A 1 274 ? 154.499 113.344 128.659 1.00 33.57  ? 274 ALA A CB  1 
ATOM   2042  N N   . PRO A 1 275 ? 155.702 110.525 127.419 1.00 34.95  ? 275 PRO A N   1 
ATOM   2043  C CA  . PRO A 1 275 ? 155.366 109.146 127.051 1.00 34.95  ? 275 PRO A CA  1 
ATOM   2044  C C   . PRO A 1 275 ? 154.137 108.642 127.792 1.00 34.95  ? 275 PRO A C   1 
ATOM   2045  O O   . PRO A 1 275 ? 153.740 109.163 128.835 1.00 34.95  ? 275 PRO A O   1 
ATOM   2046  C CB  . PRO A 1 275 ? 156.616 108.357 127.451 1.00 34.95  ? 275 PRO A CB  1 
ATOM   2047  C CG  . PRO A 1 275 ? 157.251 109.175 128.507 1.00 34.95  ? 275 PRO A CG  1 
ATOM   2048  C CD  . PRO A 1 275 ? 156.968 110.606 128.165 1.00 34.95  ? 275 PRO A CD  1 
ATOM   2049  N N   . ILE A 1 276 ? 153.541 107.592 127.235 1.00 36.39  ? 276 ILE A N   1 
ATOM   2050  C CA  . ILE A 1 276 ? 152.319 106.989 127.754 1.00 36.39  ? 276 ILE A CA  1 
ATOM   2051  C C   . ILE A 1 276 ? 152.676 105.659 128.404 1.00 36.39  ? 276 ILE A C   1 
ATOM   2052  O O   . ILE A 1 276 ? 153.365 104.831 127.797 1.00 36.39  ? 276 ILE A O   1 
ATOM   2053  C CB  . ILE A 1 276 ? 151.275 106.801 126.640 1.00 36.39  ? 276 ILE A CB  1 
ATOM   2054  C CG1 . ILE A 1 276 ? 150.990 108.138 125.954 1.00 36.39  ? 276 ILE A CG1 1 
ATOM   2055  C CG2 . ILE A 1 276 ? 149.998 106.189 127.193 1.00 36.39  ? 276 ILE A CG2 1 
ATOM   2056  C CD1 . ILE A 1 276 ? 150.018 108.044 124.808 1.00 36.39  ? 276 ILE A CD1 1 
ATOM   2057  N N   . GLU A 1 277 ? 152.208 105.455 129.634 1.00 41.67  ? 277 GLU A N   1 
ATOM   2058  C CA  . GLU A 1 277 ? 152.527 104.269 130.419 1.00 41.67  ? 277 GLU A CA  1 
ATOM   2059  C C   . GLU A 1 277 ? 151.254 103.684 131.016 1.00 41.67  ? 277 GLU A C   1 
ATOM   2060  O O   . GLU A 1 277 ? 150.204 104.328 131.055 1.00 41.67  ? 277 GLU A O   1 
ATOM   2061  C CB  . GLU A 1 277 ? 153.532 104.587 131.534 1.00 41.67  ? 277 GLU A CB  1 
ATOM   2062  C CG  . GLU A 1 277 ? 154.756 105.357 131.069 1.00 41.67  ? 277 GLU A CG  1 
ATOM   2063  C CD  . GLU A 1 277 ? 155.915 104.449 130.712 1.00 41.67  ? 277 GLU A CD  1 
ATOM   2064  O OE1 . GLU A 1 277 ? 156.379 103.701 131.599 1.00 41.67  ? 277 GLU A OE1 1 
ATOM   2065  O OE2 . GLU A 1 277 ? 156.364 104.483 129.546 1.00 41.67  ? 277 GLU A OE2 1 
ATOM   2066  N N   . THR A 1 278 ? 151.365 102.446 131.493 1.00 42.75  ? 278 THR A N   1 
ATOM   2067  C CA  . THR A 1 278 ? 150.240 101.717 132.074 1.00 42.75  ? 278 THR A CA  1 
ATOM   2068  C C   . THR A 1 278 ? 150.110 102.086 133.549 1.00 42.75  ? 278 THR A C   1 
ATOM   2069  O O   . THR A 1 278 ? 150.906 101.640 134.380 1.00 42.75  ? 278 THR A O   1 
ATOM   2070  C CB  . THR A 1 278 ? 150.433 100.212 131.905 1.00 42.75  ? 278 THR A CB  1 
ATOM   2071  O OG1 . THR A 1 278 ? 150.469 99.884  130.511 1.00 42.75  ? 278 THR A OG1 1 
ATOM   2072  C CG2 . THR A 1 278 ? 149.298 99.450  132.566 1.00 42.75  ? 278 THR A CG2 1 
ATOM   2073  N N   . CYS A 1 279 ? 149.107 102.895 133.871 1.00 42.64  ? 279 CYS A N   1 
ATOM   2074  C CA  . CYS A 1 279 ? 148.817 103.308 135.241 1.00 42.64  ? 279 CYS A CA  1 
ATOM   2075  C C   . CYS A 1 279 ? 147.423 103.925 135.248 1.00 42.64  ? 279 CYS A C   1 
ATOM   2076  O O   . CYS A 1 279 ? 146.735 103.958 134.224 1.00 42.64  ? 279 CYS A O   1 
ATOM   2077  C CB  . CYS A 1 279 ? 149.869 104.281 135.778 1.00 42.64  ? 279 CYS A CB  1 
ATOM   2078  S SG  . CYS A 1 279 ? 150.377 105.571 134.620 1.00 42.64  ? 279 CYS A SG  1 
ATOM   2079  N N   . ILE A 1 280 ? 147.009 104.417 136.413 1.00 39.56  ? 280 ILE A N   1 
ATOM   2080  C CA  . ILE A 1 280 ? 145.677 104.979 136.608 1.00 39.56  ? 280 ILE A CA  1 
ATOM   2081  C C   . ILE A 1 280 ? 145.817 106.398 137.138 1.00 39.56  ? 280 ILE A C   1 
ATOM   2082  O O   . ILE A 1 280 ? 146.546 106.635 138.108 1.00 39.56  ? 280 ILE A O   1 
ATOM   2083  C CB  . ILE A 1 280 ? 144.831 104.122 137.565 1.00 39.56  ? 280 ILE A CB  1 
ATOM   2084  C CG1 . ILE A 1 280 ? 144.776 102.674 137.078 1.00 39.56  ? 280 ILE A CG1 1 
ATOM   2085  C CG2 . ILE A 1 280 ? 143.429 104.693 137.692 1.00 39.56  ? 280 ILE A CG2 1 
ATOM   2086  C CD1 . ILE A 1 280 ? 143.760 101.829 137.804 1.00 39.56  ? 280 ILE A CD1 1 
ATOM   2087  N N   . SER A 1 281 ? 145.114 107.335 136.506 1.00 37.25  ? 281 SER A N   1 
ATOM   2088  C CA  . SER A 1 281 ? 145.105 108.731 136.918 1.00 37.25  ? 281 SER A CA  1 
ATOM   2089  C C   . SER A 1 281 ? 143.943 109.434 136.235 1.00 37.25  ? 281 SER A C   1 
ATOM   2090  O O   . SER A 1 281 ? 143.680 109.196 135.055 1.00 37.25  ? 281 SER A O   1 
ATOM   2091  C CB  . SER A 1 281 ? 146.427 109.426 136.571 1.00 37.25  ? 281 SER A CB  1 
ATOM   2092  O OG  . SER A 1 281 ? 146.560 110.649 137.271 1.00 37.25  ? 281 SER A OG  1 
ATOM   2093  N N   . GLU A 1 282 ? 143.259 110.298 136.978 1.00 37.65  ? 282 GLU A N   1 
ATOM   2094  C CA  . GLU A 1 282 ? 142.095 111.003 136.459 1.00 37.65  ? 282 GLU A CA  1 
ATOM   2095  C C   . GLU A 1 282 ? 142.423 112.357 135.841 1.00 37.65  ? 282 GLU A C   1 
ATOM   2096  O O   . GLU A 1 282 ? 141.569 112.919 135.150 1.00 37.65  ? 282 GLU A O   1 
ATOM   2097  C CB  . GLU A 1 282 ? 141.057 111.196 137.570 1.00 37.65  ? 282 GLU A CB  1 
ATOM   2098  C CG  . GLU A 1 282 ? 140.381 109.914 138.021 1.00 37.65  ? 282 GLU A CG  1 
ATOM   2099  C CD  . GLU A 1 282 ? 139.081 109.649 137.289 1.00 37.65  ? 282 GLU A CD  1 
ATOM   2100  O OE1 . GLU A 1 282 ? 138.684 110.486 136.451 1.00 37.65  ? 282 GLU A OE1 1 
ATOM   2101  O OE2 . GLU A 1 282 ? 138.455 108.601 137.551 1.00 37.65  ? 282 GLU A OE2 1 
ATOM   2102  N N   . CYS A 1 283 ? 143.623 112.896 136.060 1.00 33.86  ? 283 CYS A N   1 
ATOM   2103  C CA  . CYS A 1 283 ? 143.970 114.233 135.587 1.00 33.86  ? 283 CYS A CA  1 
ATOM   2104  C C   . CYS A 1 283 ? 145.228 114.176 134.734 1.00 33.86  ? 283 CYS A C   1 
ATOM   2105  O O   . CYS A 1 283 ? 146.287 113.749 135.210 1.00 33.86  ? 283 CYS A O   1 
ATOM   2106  C CB  . CYS A 1 283 ? 144.165 115.204 136.754 1.00 33.86  ? 283 CYS A CB  1 
ATOM   2107  S SG  . CYS A 1 283 ? 144.590 116.881 136.228 1.00 33.86  ? 283 CYS A SG  1 
ATOM   2108  N N   . ILE A 1 284 ? 145.115 114.660 133.497 1.00 29.84  ? 284 ILE A N   1 
ATOM   2109  C CA  . ILE A 1 284 ? 146.191 114.664 132.514 1.00 29.84  ? 284 ILE A CA  1 
ATOM   2110  C C   . ILE A 1 284 ? 146.517 116.110 132.160 1.00 29.84  ? 284 ILE A C   1 
ATOM   2111  O O   . ILE A 1 284 ? 145.608 116.914 131.927 1.00 29.84  ? 284 ILE A O   1 
ATOM   2112  C CB  . ILE A 1 284 ? 145.799 113.876 131.248 1.00 29.84  ? 284 ILE A CB  1 
ATOM   2113  C CG1 . ILE A 1 284 ? 145.450 112.429 131.598 1.00 29.84  ? 284 ILE A CG1 1 
ATOM   2114  C CG2 . ILE A 1 284 ? 146.907 113.930 130.203 1.00 29.84  ? 284 ILE A CG2 1 
ATOM   2115  C CD1 . ILE A 1 284 ? 144.606 111.737 130.554 1.00 29.84  ? 284 ILE A CD1 1 
ATOM   2116  N N   . THR A 1 285 ? 147.802 116.436 132.118 1.00 28.25  ? 285 THR A N   1 
ATOM   2117  C CA  . THR A 1 285 ? 148.321 117.715 131.657 1.00 28.25  ? 285 THR A CA  1 
ATOM   2118  C C   . THR A 1 285 ? 149.388 117.430 130.617 1.00 28.25  ? 285 THR A C   1 
ATOM   2119  O O   . THR A 1 285 ? 149.841 116.290 130.476 1.00 28.25  ? 285 THR A O   1 
ATOM   2120  C CB  . THR A 1 285 ? 148.912 118.534 132.822 1.00 28.25  ? 285 THR A CB  1 
ATOM   2121  O OG1 . THR A 1 285 ? 150.226 118.060 133.134 1.00 28.25  ? 285 THR A OG1 1 
ATOM   2122  C CG2 . THR A 1 285 ? 148.036 118.444 134.063 1.00 28.25  ? 285 THR A CG2 1 
ATOM   2123  N N   . PRO A 1 286 ? 149.805 118.441 129.849 1.00 28.08  ? 286 PRO A N   1 
ATOM   2124  C CA  . PRO A 1 286 ? 150.916 118.222 128.908 1.00 28.08  ? 286 PRO A CA  1 
ATOM   2125  C C   . PRO A 1 286 ? 152.206 117.774 129.575 1.00 28.08  ? 286 PRO A C   1 
ATOM   2126  O O   . PRO A 1 286 ? 153.045 117.162 128.906 1.00 28.08  ? 286 PRO A O   1 
ATOM   2127  C CB  . PRO A 1 286 ? 151.080 119.589 128.234 1.00 28.08  ? 286 PRO A CB  1 
ATOM   2128  C CG  . PRO A 1 286 ? 149.749 120.219 128.350 1.00 28.08  ? 286 PRO A CG  1 
ATOM   2129  C CD  . PRO A 1 286 ? 149.183 119.762 129.654 1.00 28.08  ? 286 PRO A CD  1 
ATOM   2130  N N   . ASN A 1 287 ? 152.399 118.062 130.863 1.00 31.37  ? 287 ASN A N   1 
ATOM   2131  C CA  . ASN A 1 287 ? 153.565 117.573 131.587 1.00 31.37  ? 287 ASN A CA  1 
ATOM   2132  C C   . ASN A 1 287 ? 153.431 116.121 132.027 1.00 31.37  ? 287 ASN A C   1 
ATOM   2133  O O   . ASN A 1 287 ? 154.428 115.530 132.451 1.00 31.37  ? 287 ASN A O   1 
ATOM   2134  C CB  . ASN A 1 287 ? 153.834 118.435 132.825 1.00 31.37  ? 287 ASN A CB  1 
ATOM   2135  C CG  . ASN A 1 287 ? 153.866 119.919 132.520 1.00 31.37  ? 287 ASN A CG  1 
ATOM   2136  O OD1 . ASN A 1 287 ? 152.897 120.484 132.019 1.00 31.37  ? 287 ASN A OD1 1 
ATOM   2137  N ND2 . ASN A 1 287 ? 154.986 120.560 132.831 1.00 31.37  ? 287 ASN A ND2 1 
ATOM   2138  N N   . GLY A 1 288 ? 152.241 115.537 131.947 1.00 30.26  ? 288 GLY A N   1 
ATOM   2139  C CA  . GLY A 1 288 ? 151.982 114.202 132.440 1.00 30.26  ? 288 GLY A CA  1 
ATOM   2140  C C   . GLY A 1 288 ? 150.752 114.163 133.318 1.00 30.26  ? 288 GLY A C   1 
ATOM   2141  O O   . GLY A 1 288 ? 150.012 115.134 133.450 1.00 30.26  ? 288 GLY A O   1 
ATOM   2142  N N   . SER A 1 289 ? 150.522 112.999 133.911 1.00 31.80  ? 289 SER A N   1 
ATOM   2143  C CA  . SER A 1 289 ? 149.397 112.841 134.818 1.00 31.80  ? 289 SER A CA  1 
ATOM   2144  C C   . SER A 1 289 ? 149.747 113.380 136.199 1.00 31.80  ? 289 SER A C   1 
ATOM   2145  O O   . SER A 1 289 ? 150.900 113.328 136.634 1.00 31.80  ? 289 SER A O   1 
ATOM   2146  C CB  . SER A 1 289 ? 148.987 111.373 134.917 1.00 31.80  ? 289 SER A CB  1 
ATOM   2147  O OG  . SER A 1 289 ? 148.391 110.932 133.714 1.00 31.80  ? 289 SER A OG  1 
ATOM   2148  N N   . ILE A 1 290 ? 148.742 113.916 136.886 1.00 32.02  ? 290 ILE A N   1 
ATOM   2149  C CA  . ILE A 1 290 ? 148.963 114.406 138.248 1.00 32.02  ? 290 ILE A CA  1 
ATOM   2150  C C   . ILE A 1 290 ? 147.868 113.901 139.181 1.00 32.02  ? 290 ILE A C   1 
ATOM   2151  O O   . ILE A 1 290 ? 146.717 113.736 138.755 1.00 32.02  ? 290 ILE A O   1 
ATOM   2152  C CB  . ILE A 1 290 ? 149.049 115.943 138.296 1.00 32.02  ? 290 ILE A CB  1 
ATOM   2153  C CG1 . ILE A 1 290 ? 147.782 116.583 137.732 1.00 32.02  ? 290 ILE A CG1 1 
ATOM   2154  C CG2 . ILE A 1 290 ? 150.290 116.449 137.569 1.00 32.02  ? 290 ILE A CG2 1 
ATOM   2155  C CD1 . ILE A 1 290 ? 147.682 118.063 138.010 1.00 32.02  ? 290 ILE A CD1 1 
ATOM   2156  N N   . PRO A 1 291 ? 148.180 113.641 140.451 1.00 33.34  ? 291 PRO A N   1 
ATOM   2157  C CA  . PRO A 1 291 ? 147.129 113.288 141.411 1.00 33.34  ? 291 PRO A CA  1 
ATOM   2158  C C   . PRO A 1 291 ? 146.233 114.478 141.710 1.00 33.34  ? 291 PRO A C   1 
ATOM   2159  O O   . PRO A 1 291 ? 146.644 115.635 141.607 1.00 33.34  ? 291 PRO A O   1 
ATOM   2160  C CB  . PRO A 1 291 ? 147.914 112.853 142.654 1.00 33.34  ? 291 PRO A CB  1 
ATOM   2161  C CG  . PRO A 1 291 ? 149.230 113.523 142.526 1.00 33.34  ? 291 PRO A CG  1 
ATOM   2162  C CD  . PRO A 1 291 ? 149.520 113.633 141.061 1.00 33.34  ? 291 PRO A CD  1 
ATOM   2163  N N   . ASN A 1 292 ? 144.990 114.184 142.087 1.00 35.89  ? 292 ASN A N   1 
ATOM   2164  C CA  . ASN A 1 292 ? 143.988 115.223 142.293 1.00 35.89  ? 292 ASN A CA  1 
ATOM   2165  C C   . ASN A 1 292 ? 143.457 115.254 143.726 1.00 35.89  ? 292 ASN A C   1 
ATOM   2166  O O   . ASN A 1 292 ? 142.329 115.688 143.960 1.00 35.89  ? 292 ASN A O   1 
ATOM   2167  C CB  . ASN A 1 292 ? 142.834 115.065 141.303 1.00 35.89  ? 292 ASN A CB  1 
ATOM   2168  C CG  . ASN A 1 292 ? 142.107 113.742 141.448 1.00 35.89  ? 292 ASN A CG  1 
ATOM   2169  O OD1 . ASN A 1 292 ? 142.493 112.887 142.241 1.00 35.89  ? 292 ASN A OD1 1 
ATOM   2170  N ND2 . ASN A 1 292 ? 141.035 113.575 140.686 1.00 35.89  ? 292 ASN A ND2 1 
ATOM   2171  N N   . ASP A 1 293 ? 144.253 114.810 144.700 1.00 37.26  ? 293 ASP A N   1 
ATOM   2172  C CA  . ASP A 1 293 ? 143.807 114.881 146.087 1.00 37.26  ? 293 ASP A CA  1 
ATOM   2173  C C   . ASP A 1 293 ? 143.915 116.284 146.674 1.00 37.26  ? 293 ASP A C   1 
ATOM   2174  O O   . ASP A 1 293 ? 143.300 116.554 147.709 1.00 37.26  ? 293 ASP A O   1 
ATOM   2175  C CB  . ASP A 1 293 ? 144.590 113.896 146.960 1.00 37.26  ? 293 ASP A CB  1 
ATOM   2176  C CG  . ASP A 1 293 ? 146.067 113.868 146.633 1.00 37.26  ? 293 ASP A CG  1 
ATOM   2177  O OD1 . ASP A 1 293 ? 146.761 114.868 146.905 1.00 37.26  ? 293 ASP A OD1 1 
ATOM   2178  O OD2 . ASP A 1 293 ? 146.537 112.838 146.110 1.00 37.26  ? 293 ASP A OD2 1 
ATOM   2179  N N   . LYS A 1 294 ? 144.663 117.171 146.045 1.00 32.75  ? 294 LYS A N   1 
ATOM   2180  C CA  . LYS A 1 294 ? 144.776 118.546 146.498 1.00 32.75  ? 294 LYS A CA  1 
ATOM   2181  C C   . LYS A 1 294 ? 143.848 119.454 145.698 1.00 32.75  ? 294 LYS A C   1 
ATOM   2182  O O   . LYS A 1 294 ? 143.536 119.165 144.541 1.00 32.75  ? 294 LYS A O   1 
ATOM   2183  C CB  . LYS A 1 294 ? 146.219 119.040 146.365 1.00 32.75  ? 294 LYS A CB  1 
ATOM   2184  C CG  . LYS A 1 294 ? 147.165 118.429 147.381 1.00 32.75  ? 294 LYS A CG  1 
ATOM   2185  C CD  . LYS A 1 294 ? 148.606 118.811 147.110 1.00 32.75  ? 294 LYS A CD  1 
ATOM   2186  C CE  . LYS A 1 294 ? 149.556 117.794 147.716 1.00 32.75  ? 294 LYS A CE  1 
ATOM   2187  N NZ  . LYS A 1 294 ? 150.924 118.341 147.900 1.00 32.75  ? 294 LYS A NZ  1 
ATOM   2188  N N   . PRO A 1 295 ? 143.382 120.559 146.289 1.00 29.30  ? 295 PRO A N   1 
ATOM   2189  C CA  . PRO A 1 295 ? 142.444 121.434 145.567 1.00 29.30  ? 295 PRO A CA  1 
ATOM   2190  C C   . PRO A 1 295 ? 143.084 122.345 144.530 1.00 29.30  ? 295 PRO A C   1 
ATOM   2191  O O   . PRO A 1 295 ? 142.360 122.868 143.673 1.00 29.30  ? 295 PRO A O   1 
ATOM   2192  C CB  . PRO A 1 295 ? 141.799 122.257 146.691 1.00 29.30  ? 295 PRO A CB  1 
ATOM   2193  C CG  . PRO A 1 295 ? 142.807 122.260 147.777 1.00 29.30  ? 295 PRO A CG  1 
ATOM   2194  C CD  . PRO A 1 295 ? 143.518 120.941 147.705 1.00 29.30  ? 295 PRO A CD  1 
ATOM   2195  N N   . PHE A 1 296 ? 144.399 122.555 144.568 1.00 27.89  ? 296 PHE A N   1 
ATOM   2196  C CA  . PHE A 1 296 ? 145.062 123.480 143.662 1.00 27.89  ? 296 PHE A CA  1 
ATOM   2197  C C   . PHE A 1 296 ? 146.301 122.831 143.062 1.00 27.89  ? 296 PHE A C   1 
ATOM   2198  O O   . PHE A 1 296 ? 146.894 121.924 143.650 1.00 27.89  ? 296 PHE A O   1 
ATOM   2199  C CB  . PHE A 1 296 ? 145.455 124.786 144.376 1.00 27.89  ? 296 PHE A CB  1 
ATOM   2200  C CG  . PHE A 1 296 ? 144.315 125.458 145.090 1.00 27.89  ? 296 PHE A CG  1 
ATOM   2201  C CD1 . PHE A 1 296 ? 143.207 125.900 144.394 1.00 27.89  ? 296 PHE A CD1 1 
ATOM   2202  C CD2 . PHE A 1 296 ? 144.356 125.648 146.460 1.00 27.89  ? 296 PHE A CD2 1 
ATOM   2203  C CE1 . PHE A 1 296 ? 142.161 126.517 145.047 1.00 27.89  ? 296 PHE A CE1 1 
ATOM   2204  C CE2 . PHE A 1 296 ? 143.310 126.265 147.119 1.00 27.89  ? 296 PHE A CE2 1 
ATOM   2205  C CZ  . PHE A 1 296 ? 142.211 126.697 146.412 1.00 27.89  ? 296 PHE A CZ  1 
ATOM   2206  N N   . GLN A 1 297 ? 146.689 123.310 141.880 1.00 26.56  ? 297 GLN A N   1 
ATOM   2207  C CA  . GLN A 1 297 ? 147.877 122.822 141.197 1.00 26.56  ? 297 GLN A CA  1 
ATOM   2208  C C   . GLN A 1 297 ? 148.575 123.980 140.497 1.00 26.56  ? 297 GLN A C   1 
ATOM   2209  O O   . GLN A 1 297 ? 147.964 124.996 140.161 1.00 26.56  ? 297 GLN A O   1 
ATOM   2210  C CB  . GLN A 1 297 ? 147.544 121.711 140.189 1.00 26.56  ? 297 GLN A CB  1 
ATOM   2211  C CG  . GLN A 1 297 ? 146.480 122.079 139.166 1.00 26.56  ? 297 GLN A CG  1 
ATOM   2212  C CD  . GLN A 1 297 ? 147.064 122.412 137.807 1.00 26.56  ? 297 GLN A CD  1 
ATOM   2213  O OE1 . GLN A 1 297 ? 148.278 122.400 137.622 1.00 26.56  ? 297 GLN A OE1 1 
ATOM   2214  N NE2 . GLN A 1 297 ? 146.199 122.718 136.850 1.00 26.56  ? 297 GLN A NE2 1 
ATOM   2215  N N   . ASN A 1 298 ? 149.877 123.802 140.281 1.00 27.60  ? 298 ASN A N   1 
ATOM   2216  C CA  . ASN A 1 298 ? 150.731 124.809 139.666 1.00 27.60  ? 298 ASN A CA  1 
ATOM   2217  C C   . ASN A 1 298 ? 151.476 124.261 138.453 1.00 27.60  ? 298 ASN A C   1 
ATOM   2218  O O   . ASN A 1 298 ? 152.414 124.904 137.970 1.00 27.60  ? 298 ASN A O   1 
ATOM   2219  C CB  . ASN A 1 298 ? 151.725 125.346 140.706 1.00 27.60  ? 298 ASN A CB  1 
ATOM   2220  C CG  . ASN A 1 298 ? 152.383 126.634 140.282 1.00 27.60  ? 298 ASN A CG  1 
ATOM   2221  O OD1 . ASN A 1 298 ? 151.752 127.504 139.688 1.00 27.60  ? 298 ASN A OD1 1 
ATOM   2222  N ND2 . ASN A 1 298 ? 153.667 126.764 140.586 1.00 27.60  ? 298 ASN A ND2 1 
ATOM   2223  N N   . VAL A 1 299 ? 151.075 123.100 137.938 1.00 27.75  ? 299 VAL A N   1 
ATOM   2224  C CA  . VAL A 1 299 ? 151.864 122.416 136.920 1.00 27.75  ? 299 VAL A CA  1 
ATOM   2225  C C   . VAL A 1 299 ? 151.613 123.008 135.536 1.00 27.75  ? 299 VAL A C   1 
ATOM   2226  O O   . VAL A 1 299 ? 152.556 123.335 134.809 1.00 27.75  ? 299 VAL A O   1 
ATOM   2227  C CB  . VAL A 1 299 ? 151.570 120.904 136.957 1.00 27.75  ? 299 VAL A CB  1 
ATOM   2228  C CG1 . VAL A 1 299 ? 152.247 120.197 135.799 1.00 27.75  ? 299 VAL A CG1 1 
ATOM   2229  C CG2 . VAL A 1 299 ? 152.023 120.314 138.284 1.00 27.75  ? 299 VAL A CG2 1 
ATOM   2230  N N   . ASN A 1 300 ? 150.347 123.157 135.150 1.00 26.76  ? 300 ASN A N   1 
ATOM   2231  C CA  . ASN A 1 300 ? 150.005 123.606 133.807 1.00 26.76  ? 300 ASN A CA  1 
ATOM   2232  C C   . ASN A 1 300 ? 148.541 124.011 133.773 1.00 26.76  ? 300 ASN A C   1 
ATOM   2233  O O   . ASN A 1 300 ? 147.693 123.318 134.336 1.00 26.76  ? 300 ASN A O   1 
ATOM   2234  C CB  . ASN A 1 300 ? 150.265 122.503 132.770 1.00 26.76  ? 300 ASN A CB  1 
ATOM   2235  C CG  . ASN A 1 300 ? 150.465 123.049 131.373 1.00 26.76  ? 300 ASN A CG  1 
ATOM   2236  O OD1 . ASN A 1 300 ? 149.632 123.789 130.857 1.00 26.76  ? 300 ASN A OD1 1 
ATOM   2237  N ND2 . ASN A 1 300 ? 151.574 122.679 130.751 1.00 26.76  ? 300 ASN A ND2 1 
ATOM   2238  N N   . LYS A 1 301 ? 148.250 125.121 133.095 1.00 27.17  ? 301 LYS A N   1 
ATOM   2239  C CA  . LYS A 1 301 ? 146.872 125.568 132.938 1.00 27.17  ? 301 LYS A CA  1 
ATOM   2240  C C   . LYS A 1 301 ? 146.101 124.776 131.887 1.00 27.17  ? 301 LYS A C   1 
ATOM   2241  O O   . LYS A 1 301 ? 144.885 124.951 131.778 1.00 27.17  ? 301 LYS A O   1 
ATOM   2242  C CB  . LYS A 1 301 ? 146.836 127.062 132.603 1.00 27.17  ? 301 LYS A CB  1 
ATOM   2243  C CG  . LYS A 1 301 ? 147.448 127.437 131.270 1.00 27.17  ? 301 LYS A CG  1 
ATOM   2244  C CD  . LYS A 1 301 ? 147.672 128.937 131.184 1.00 27.17  ? 301 LYS A CD  1 
ATOM   2245  C CE  . LYS A 1 301 ? 148.125 129.353 129.795 1.00 27.17  ? 301 LYS A CE  1 
ATOM   2246  N NZ  . LYS A 1 301 ? 149.600 129.537 129.715 1.00 27.17  ? 301 LYS A NZ  1 
ATOM   2247  N N   . ILE A 1 302 ? 146.767 123.916 131.122 1.00 26.54  ? 302 ILE A N   1 
ATOM   2248  C CA  . ILE A 1 302 ? 146.096 123.012 130.194 1.00 26.54  ? 302 ILE A CA  1 
ATOM   2249  C C   . ILE A 1 302 ? 145.860 121.688 130.912 1.00 26.54  ? 302 ILE A C   1 
ATOM   2250  O O   . ILE A 1 302 ? 146.810 121.046 131.369 1.00 26.54  ? 302 ILE A O   1 
ATOM   2251  C CB  . ILE A 1 302 ? 146.926 122.807 128.917 1.00 26.54  ? 302 ILE A CB  1 
ATOM   2252  C CG1 . ILE A 1 302 ? 147.043 124.118 128.141 1.00 26.54  ? 302 ILE A CG1 1 
ATOM   2253  C CG2 . ILE A 1 302 ? 146.311 121.725 128.048 1.00 26.54  ? 302 ILE A CG2 1 
ATOM   2254  C CD1 . ILE A 1 302 ? 148.234 124.175 127.218 1.00 26.54  ? 302 ILE A CD1 1 
ATOM   2255  N N   . THR A 1 303 ? 144.596 121.281 131.020 1.00 29.17  ? 303 THR A N   1 
ATOM   2256  C CA  . THR A 1 303 ? 144.235 120.079 131.762 1.00 29.17  ? 303 THR A CA  1 
ATOM   2257  C C   . THR A 1 303 ? 143.100 119.352 131.056 1.00 29.17  ? 303 THR A C   1 
ATOM   2258  O O   . THR A 1 303 ? 142.357 119.932 130.262 1.00 29.17  ? 303 THR A O   1 
ATOM   2259  C CB  . THR A 1 303 ? 143.813 120.394 133.212 1.00 29.17  ? 303 THR A CB  1 
ATOM   2260  O OG1 . THR A 1 303 ? 142.866 121.468 133.222 1.00 29.17  ? 303 THR A OG1 1 
ATOM   2261  C CG2 . THR A 1 303 ? 145.015 120.774 134.068 1.00 29.17  ? 303 THR A CG2 1 
ATOM   2262  N N   . TYR A 1 304 ? 142.977 118.061 131.360 1.00 29.51  ? 304 TYR A N   1 
ATOM   2263  C CA  . TYR A 1 304 ? 141.862 117.243 130.903 1.00 29.51  ? 304 TYR A CA  1 
ATOM   2264  C C   . TYR A 1 304 ? 141.462 116.293 132.021 1.00 29.51  ? 304 TYR A C   1 
ATOM   2265  O O   . TYR A 1 304 ? 142.319 115.615 132.594 1.00 29.51  ? 304 TYR A O   1 
ATOM   2266  C CB  . TYR A 1 304 ? 142.223 116.452 129.638 1.00 29.51  ? 304 TYR A CB  1 
ATOM   2267  C CG  . TYR A 1 304 ? 141.108 115.566 129.125 1.00 29.51  ? 304 TYR A CG  1 
ATOM   2268  C CD1 . TYR A 1 304 ? 140.134 116.070 128.275 1.00 29.51  ? 304 TYR A CD1 1 
ATOM   2269  C CD2 . TYR A 1 304 ? 141.031 114.228 129.487 1.00 29.51  ? 304 TYR A CD2 1 
ATOM   2270  C CE1 . TYR A 1 304 ? 139.115 115.269 127.802 1.00 29.51  ? 304 TYR A CE1 1 
ATOM   2271  C CE2 . TYR A 1 304 ? 140.013 113.420 129.023 1.00 29.51  ? 304 TYR A CE2 1 
ATOM   2272  C CZ  . TYR A 1 304 ? 139.058 113.946 128.179 1.00 29.51  ? 304 TYR A CZ  1 
ATOM   2273  O OH  . TYR A 1 304 ? 138.041 113.149 127.708 1.00 29.51  ? 304 TYR A OH  1 
ATOM   2274  N N   . GLY A 1 305 ? 140.168 116.242 132.327 1.00 33.50  ? 305 GLY A N   1 
ATOM   2275  C CA  . GLY A 1 305 ? 139.663 115.322 133.329 1.00 33.50  ? 305 GLY A CA  1 
ATOM   2276  C C   . GLY A 1 305 ? 139.262 115.977 134.636 1.00 33.50  ? 305 GLY A C   1 
ATOM   2277  O O   . GLY A 1 305 ? 138.833 117.133 134.652 1.00 33.50  ? 305 GLY A O   1 
ATOM   2278  N N   . ALA A 1 306 ? 139.391 115.242 135.740 1.00 35.49  ? 306 ALA A N   1 
ATOM   2279  C CA  . ALA A 1 306 ? 139.060 115.748 137.074 1.00 35.49  ? 306 ALA A CA  1 
ATOM   2280  C C   . ALA A 1 306 ? 140.335 116.298 137.700 1.00 35.49  ? 306 ALA A C   1 
ATOM   2281  O O   . ALA A 1 306 ? 141.177 115.542 138.187 1.00 35.49  ? 306 ALA A O   1 
ATOM   2282  C CB  . ALA A 1 306 ? 138.446 114.647 137.931 1.00 35.49  ? 306 ALA A CB  1 
ATOM   2283  N N   . CYS A 1 307 ? 140.476 117.617 137.699 1.00 33.45  ? 307 CYS A N   1 
ATOM   2284  C CA  . CYS A 1 307 ? 141.752 118.241 137.998 1.00 33.45  ? 307 CYS A CA  1 
ATOM   2285  C C   . CYS A 1 307 ? 141.607 119.322 139.058 1.00 33.45  ? 307 CYS A C   1 
ATOM   2286  O O   . CYS A 1 307 ? 140.538 119.921 139.201 1.00 33.45  ? 307 CYS A O   1 
ATOM   2287  C CB  . CYS A 1 307 ? 142.360 118.854 136.728 1.00 33.45  ? 307 CYS A CB  1 
ATOM   2288  S SG  . CYS A 1 307 ? 142.859 117.639 135.488 1.00 33.45  ? 307 CYS A SG  1 
ATOM   2289  N N   . PRO A 1 308 ? 142.667 119.585 139.818 1.00 30.05  ? 308 PRO A N   1 
ATOM   2290  C CA  . PRO A 1 308 ? 142.674 120.757 140.697 1.00 30.05  ? 308 PRO A CA  1 
ATOM   2291  C C   . PRO A 1 308 ? 142.733 122.046 139.893 1.00 30.05  ? 308 PRO A C   1 
ATOM   2292  O O   . PRO A 1 308 ? 143.173 122.078 138.742 1.00 30.05  ? 308 PRO A O   1 
ATOM   2293  C CB  . PRO A 1 308 ? 143.943 120.572 141.539 1.00 30.05  ? 308 PRO A CB  1 
ATOM   2294  C CG  . PRO A 1 308 ? 144.383 119.161 141.308 1.00 30.05  ? 308 PRO A CG  1 
ATOM   2295  C CD  . PRO A 1 308 ? 143.888 118.777 139.960 1.00 30.05  ? 308 PRO A CD  1 
ATOM   2296  N N   . LYS A 1 309 ? 142.269 123.122 140.519 1.00 29.32  ? 309 LYS A N   1 
ATOM   2297  C CA  . LYS A 1 309 ? 142.281 124.425 139.869 1.00 29.32  ? 309 LYS A CA  1 
ATOM   2298  C C   . LYS A 1 309 ? 143.701 124.972 139.778 1.00 29.32  ? 309 LYS A C   1 
ATOM   2299  O O   . LYS A 1 309 ? 144.500 124.833 140.707 1.00 29.32  ? 309 LYS A O   1 
ATOM   2300  C CB  . LYS A 1 309 ? 141.389 125.402 140.630 1.00 29.32  ? 309 LYS A CB  1 
ATOM   2301  C CG  . LYS A 1 309 ? 139.951 124.950 140.754 1.00 29.32  ? 309 LYS A CG  1 
ATOM   2302  C CD  . LYS A 1 309 ? 139.085 126.025 141.375 1.00 29.32  ? 309 LYS A CD  1 
ATOM   2303  C CE  . LYS A 1 309 ? 137.667 125.532 141.585 1.00 29.32  ? 309 LYS A CE  1 
ATOM   2304  N NZ  . LYS A 1 309 ? 137.589 124.522 142.673 1.00 29.32  ? 309 LYS A NZ  1 
ATOM   2305  N N   . TYR A 1 310 ? 144.010 125.606 138.652 1.00 25.20  ? 310 TYR A N   1 
ATOM   2306  C CA  . TYR A 1 310 ? 145.333 126.174 138.441 1.00 25.20  ? 310 TYR A CA  1 
ATOM   2307  C C   . TYR A 1 310 ? 145.465 127.501 139.179 1.00 25.20  ? 310 TYR A C   1 
ATOM   2308  O O   . TYR A 1 310 ? 144.572 128.350 139.116 1.00 25.20  ? 310 TYR A O   1 
ATOM   2309  C CB  . TYR A 1 310 ? 145.600 126.369 136.949 1.00 25.20  ? 310 TYR A CB  1 
ATOM   2310  C CG  . TYR A 1 310 ? 146.967 126.938 136.655 1.00 25.20  ? 310 TYR A CG  1 
ATOM   2311  C CD1 . TYR A 1 310 ? 148.097 126.132 136.681 1.00 25.20  ? 310 TYR A CD1 1 
ATOM   2312  C CD2 . TYR A 1 310 ? 147.130 128.284 136.365 1.00 25.20  ? 310 TYR A CD2 1 
ATOM   2313  C CE1 . TYR A 1 310 ? 149.348 126.650 136.419 1.00 25.20  ? 310 TYR A CE1 1 
ATOM   2314  C CE2 . TYR A 1 310 ? 148.377 128.811 136.103 1.00 25.20  ? 310 TYR A CE2 1 
ATOM   2315  C CZ  . TYR A 1 310 ? 149.482 127.990 136.129 1.00 25.20  ? 310 TYR A CZ  1 
ATOM   2316  O OH  . TYR A 1 310 ? 150.723 128.516 135.871 1.00 25.20  ? 310 TYR A OH  1 
ATOM   2317  N N   . VAL A 1 311 ? 146.584 127.677 139.882 1.00 25.07  ? 311 VAL A N   1 
ATOM   2318  C CA  . VAL A 1 311 ? 146.906 128.919 140.569 1.00 25.07  ? 311 VAL A CA  1 
ATOM   2319  C C   . VAL A 1 311 ? 148.359 129.272 140.272 1.00 25.07  ? 311 VAL A C   1 
ATOM   2320  O O   . VAL A 1 311 ? 149.127 128.460 139.760 1.00 25.07  ? 311 VAL A O   1 
ATOM   2321  C CB  . VAL A 1 311 ? 146.666 128.841 142.094 1.00 25.07  ? 311 VAL A CB  1 
ATOM   2322  C CG1 . VAL A 1 311 ? 145.183 128.731 142.400 1.00 25.07  ? 311 VAL A CG1 1 
ATOM   2323  C CG2 . VAL A 1 311 ? 147.436 127.678 142.708 1.00 25.07  ? 311 VAL A CG2 1 
ATOM   2324  N N   . LYS A 1 312 ? 148.725 130.510 140.601 1.00 28.50  ? 312 LYS A N   1 
ATOM   2325  C CA  . LYS A 1 312 ? 150.076 131.005 140.375 1.00 28.50  ? 312 LYS A CA  1 
ATOM   2326  C C   . LYS A 1 312 ? 151.041 130.695 141.512 1.00 28.50  ? 312 LYS A C   1 
ATOM   2327  O O   . LYS A 1 312 ? 152.256 130.785 141.310 1.00 28.50  ? 312 LYS A O   1 
ATOM   2328  C CB  . LYS A 1 312 ? 150.050 132.520 140.152 1.00 28.50  ? 312 LYS A CB  1 
ATOM   2329  C CG  . LYS A 1 312 ? 150.009 132.935 138.697 1.00 28.50  ? 312 LYS A CG  1 
ATOM   2330  C CD  . LYS A 1 312 ? 149.081 134.114 138.483 1.00 28.50  ? 312 LYS A CD  1 
ATOM   2331  C CE  . LYS A 1 312 ? 149.382 135.248 139.440 1.00 28.50  ? 312 LYS A CE  1 
ATOM   2332  N NZ  . LYS A 1 312 ? 148.174 136.068 139.719 1.00 28.50  ? 312 LYS A NZ  1 
ATOM   2333  N N   . GLN A 1 313 ? 150.541 130.340 142.692 1.00 29.34  ? 313 GLN A N   1 
ATOM   2334  C CA  . GLN A 1 313 ? 151.402 130.101 143.842 1.00 29.34  ? 313 GLN A CA  1 
ATOM   2335  C C   . GLN A 1 313 ? 151.990 128.696 143.796 1.00 29.34  ? 313 GLN A C   1 
ATOM   2336  O O   . GLN A 1 313 ? 151.319 127.741 143.397 1.00 29.34  ? 313 GLN A O   1 
ATOM   2337  C CB  . GLN A 1 313 ? 150.618 130.295 145.141 1.00 29.34  ? 313 GLN A CB  1 
ATOM   2338  C CG  . GLN A 1 313 ? 150.107 131.709 145.353 1.00 29.34  ? 313 GLN A CG  1 
ATOM   2339  C CD  . GLN A 1 313 ? 148.652 131.876 144.953 1.00 29.34  ? 313 GLN A CD  1 
ATOM   2340  O OE1 . GLN A 1 313 ? 148.213 131.355 143.930 1.00 29.34  ? 313 GLN A OE1 1 
ATOM   2341  N NE2 . GLN A 1 313 ? 147.900 132.611 145.758 1.00 29.34  ? 313 GLN A NE2 1 
ATOM   2342  N N   . ASN A 1 314 ? 153.250 128.571 144.214 1.00 34.14  ? 314 ASN A N   1 
ATOM   2343  C CA  . ASN A 1 314 ? 153.878 127.258 144.276 1.00 34.14  ? 314 ASN A CA  1 
ATOM   2344  C C   . ASN A 1 314 ? 153.713 126.573 145.626 1.00 34.14  ? 314 ASN A C   1 
ATOM   2345  O O   . ASN A 1 314 ? 154.039 125.387 145.737 1.00 34.14  ? 314 ASN A O   1 
ATOM   2346  C CB  . ASN A 1 314 ? 155.372 127.346 143.927 1.00 34.14  ? 314 ASN A CB  1 
ATOM   2347  C CG  . ASN A 1 314 ? 156.088 128.461 144.660 1.00 34.14  ? 314 ASN A CG  1 
ATOM   2348  O OD1 . ASN A 1 314 ? 156.381 128.350 145.849 1.00 34.14  ? 314 ASN A OD1 1 
ATOM   2349  N ND2 . ASN A 1 314 ? 156.394 129.537 143.946 1.00 34.14  ? 314 ASN A ND2 1 
ATOM   2350  N N   . THR A 1 315 ? 153.205 127.267 146.644 1.00 33.56  ? 315 THR A N   1 
ATOM   2351  C CA  . THR A 1 315 ? 152.986 126.637 147.940 1.00 33.56  ? 315 THR A CA  1 
ATOM   2352  C C   . THR A 1 315 ? 151.938 127.412 148.730 1.00 33.56  ? 315 THR A C   1 
ATOM   2353  O O   . THR A 1 315 ? 151.911 128.643 148.699 1.00 33.56  ? 315 THR A O   1 
ATOM   2354  C CB  . THR A 1 315 ? 154.289 126.535 148.749 1.00 33.56  ? 315 THR A CB  1 
ATOM   2355  O OG1 . THR A 1 315 ? 154.007 125.995 150.046 1.00 33.56  ? 315 THR A OG1 1 
ATOM   2356  C CG2 . THR A 1 315 ? 154.950 127.898 148.900 1.00 33.56  ? 315 THR A CG2 1 
ATOM   2357  N N   . LEU A 1 316 ? 151.079 126.672 149.429 1.00 32.78  ? 316 LEU A N   1 
ATOM   2358  C CA  . LEU A 1 316 ? 150.096 127.241 150.348 1.00 32.78  ? 316 LEU A CA  1 
ATOM   2359  C C   . LEU A 1 316 ? 149.896 126.247 151.481 1.00 32.78  ? 316 LEU A C   1 
ATOM   2360  O O   . LEU A 1 316 ? 149.531 125.095 151.231 1.00 32.78  ? 316 LEU A O   1 
ATOM   2361  C CB  . LEU A 1 316 ? 148.766 127.530 149.645 1.00 32.78  ? 316 LEU A CB  1 
ATOM   2362  C CG  . LEU A 1 316 ? 148.674 128.732 148.703 1.00 32.78  ? 316 LEU A CG  1 
ATOM   2363  C CD1 . LEU A 1 316 ? 147.395 128.665 147.888 1.00 32.78  ? 316 LEU A CD1 1 
ATOM   2364  C CD2 . LEU A 1 316 ? 148.750 130.037 149.471 1.00 32.78  ? 316 LEU A CD2 1 
ATOM   2365  N N   . LYS A 1 317 ? 150.126 126.681 152.716 1.00 34.87  ? 317 LYS A N   1 
ATOM   2366  C CA  . LYS A 1 317 ? 150.090 125.800 153.877 1.00 34.87  ? 317 LYS A CA  1 
ATOM   2367  C C   . LYS A 1 317 ? 148.842 126.066 154.706 1.00 34.87  ? 317 LYS A C   1 
ATOM   2368  O O   . LYS A 1 317 ? 148.590 127.206 155.108 1.00 34.87  ? 317 LYS A O   1 
ATOM   2369  C CB  . LYS A 1 317 ? 151.342 125.984 154.737 1.00 34.87  ? 317 LYS A CB  1 
ATOM   2370  C CG  . LYS A 1 317 ? 152.647 125.830 153.977 1.00 34.87  ? 317 LYS A CG  1 
ATOM   2371  C CD  . LYS A 1 317 ? 152.888 124.386 153.576 1.00 34.87  ? 317 LYS A CD  1 
ATOM   2372  C CE  . LYS A 1 317 ? 153.359 123.556 154.756 1.00 34.87  ? 317 LYS A CE  1 
ATOM   2373  N NZ  . LYS A 1 317 ? 152.989 122.124 154.615 1.00 34.87  ? 317 LYS A NZ  1 
ATOM   2374  N N   . LEU A 1 318 ? 148.076 125.012 154.973 1.00 35.90  ? 318 LEU A N   1 
ATOM   2375  C CA  . LEU A 1 318 ? 146.878 125.080 155.799 1.00 35.90  ? 318 LEU A CA  1 
ATOM   2376  C C   . LEU A 1 318 ? 147.158 124.451 157.158 1.00 35.90  ? 318 LEU A C   1 
ATOM   2377  O O   . LEU A 1 318 ? 147.603 123.302 157.233 1.00 35.90  ? 318 LEU A O   1 
ATOM   2378  C CB  . LEU A 1 318 ? 145.704 124.370 155.122 1.00 35.90  ? 318 LEU A CB  1 
ATOM   2379  C CG  . LEU A 1 318 ? 144.369 124.420 155.866 1.00 35.90  ? 318 LEU A CG  1 
ATOM   2380  C CD1 . LEU A 1 318 ? 143.621 125.702 155.549 1.00 35.90  ? 318 LEU A CD1 1 
ATOM   2381  C CD2 . LEU A 1 318 ? 143.521 123.209 155.540 1.00 35.90  ? 318 LEU A CD2 1 
ATOM   2382  N N   . ALA A 1 319 ? 146.898 125.205 158.223 1.00 39.57  ? 319 ALA A N   1 
ATOM   2383  C CA  . ALA A 1 319 ? 147.159 124.725 159.573 1.00 39.57  ? 319 ALA A CA  1 
ATOM   2384  C C   . ALA A 1 319 ? 146.167 123.640 159.974 1.00 39.57  ? 319 ALA A C   1 
ATOM   2385  O O   . ALA A 1 319 ? 144.966 123.745 159.713 1.00 39.57  ? 319 ALA A O   1 
ATOM   2386  C CB  . ALA A 1 319 ? 147.093 125.880 160.570 1.00 39.57  ? 319 ALA A CB  1 
ATOM   2387  N N   . THR A 1 320 ? 146.678 122.593 160.625 1.00 46.39  ? 320 THR A N   1 
ATOM   2388  C CA  . THR A 1 320 ? 145.840 121.528 161.164 1.00 46.39  ? 320 THR A CA  1 
ATOM   2389  C C   . THR A 1 320 ? 146.116 121.288 162.645 1.00 46.39  ? 320 THR A C   1 
ATOM   2390  O O   . THR A 1 320 ? 145.841 120.197 163.152 1.00 46.39  ? 320 THR A O   1 
ATOM   2391  C CB  . THR A 1 320 ? 146.023 120.229 160.373 1.00 46.39  ? 320 THR A CB  1 
ATOM   2392  O OG1 . THR A 1 320 ? 147.418 119.939 160.230 1.00 46.39  ? 320 THR A OG1 1 
ATOM   2393  C CG2 . THR A 1 320 ? 145.394 120.352 158.994 1.00 46.39  ? 320 THR A CG2 1 
ATOM   2394  N N   . GLY A 1 321 ? 146.648 122.286 163.347 1.00 50.34  ? 321 GLY A N   1 
ATOM   2395  C CA  . GLY A 1 321 ? 146.936 122.174 164.761 1.00 50.34  ? 321 GLY A CA  1 
ATOM   2396  C C   . GLY A 1 321 ? 146.993 123.545 165.398 1.00 50.34  ? 321 GLY A C   1 
ATOM   2397  O O   . GLY A 1 321 ? 146.902 124.571 164.722 1.00 50.34  ? 321 GLY A O   1 
ATOM   2398  N N   . MET A 1 322 ? 147.148 123.554 166.718 1.00 56.00  ? 322 MET A N   1 
ATOM   2399  C CA  . MET A 1 322 ? 147.184 124.792 167.479 1.00 56.00  ? 322 MET A CA  1 
ATOM   2400  C C   . MET A 1 322 ? 148.554 125.457 167.361 1.00 56.00  ? 322 MET A C   1 
ATOM   2401  O O   . MET A 1 322 ? 149.497 124.907 166.788 1.00 56.00  ? 322 MET A O   1 
ATOM   2402  C CB  . MET A 1 322 ? 146.850 124.523 168.944 1.00 56.00  ? 322 MET A CB  1 
ATOM   2403  C CG  . MET A 1 322 ? 147.495 123.265 169.493 1.00 56.00  ? 322 MET A CG  1 
ATOM   2404  S SD  . MET A 1 322 ? 147.606 123.250 171.290 1.00 56.00  ? 322 MET A SD  1 
ATOM   2405  C CE  . MET A 1 322 ? 146.086 122.403 171.700 1.00 56.00  ? 322 MET A CE  1 
ATOM   2406  N N   . ARG A 1 323 ? 148.655 126.664 167.911 1.00 55.98  ? 323 ARG A N   1 
ATOM   2407  C CA  . ARG A 1 323 ? 149.928 127.371 167.924 1.00 55.98  ? 323 ARG A CA  1 
ATOM   2408  C C   . ARG A 1 323 ? 150.936 126.623 168.788 1.00 55.98  ? 323 ARG A C   1 
ATOM   2409  O O   . ARG A 1 323 ? 150.581 126.014 169.801 1.00 55.98  ? 323 ARG A O   1 
ATOM   2410  C CB  . ARG A 1 323 ? 149.744 128.800 168.434 1.00 55.98  ? 323 ARG A CB  1 
ATOM   2411  C CG  . ARG A 1 323 ? 148.885 128.917 169.676 1.00 55.98  ? 323 ARG A CG  1 
ATOM   2412  C CD  . ARG A 1 323 ? 148.964 130.311 170.279 1.00 55.98  ? 323 ARG A CD  1 
ATOM   2413  N NE  . ARG A 1 323 ? 147.979 131.218 169.704 1.00 55.98  ? 323 ARG A NE  1 
ATOM   2414  C CZ  . ARG A 1 323 ? 148.274 132.375 169.128 1.00 55.98  ? 323 ARG A CZ  1 
ATOM   2415  N NH1 . ARG A 1 323 ? 149.524 132.796 169.024 1.00 55.98  ? 323 ARG A NH1 1 
ATOM   2416  N NH2 . ARG A 1 323 ? 147.291 133.129 168.644 1.00 55.98  ? 323 ARG A NH2 1 
ATOM   2417  N N   . ASN A 1 324 ? 152.199 126.666 168.376 1.00 58.45  ? 324 ASN A N   1 
ATOM   2418  C CA  . ASN A 1 324 ? 153.273 125.921 169.024 1.00 58.45  ? 324 ASN A CA  1 
ATOM   2419  C C   . ASN A 1 324 ? 154.042 126.870 169.937 1.00 58.45  ? 324 ASN A C   1 
ATOM   2420  O O   . ASN A 1 324 ? 154.700 127.800 169.463 1.00 58.45  ? 324 ASN A O   1 
ATOM   2421  C CB  . ASN A 1 324 ? 154.190 125.292 167.976 1.00 58.45  ? 324 ASN A CB  1 
ATOM   2422  C CG  . ASN A 1 324 ? 155.007 124.143 168.527 1.00 58.45  ? 324 ASN A CG  1 
ATOM   2423  O OD1 . ASN A 1 324 ? 154.480 123.250 169.184 1.00 58.45  ? 324 ASN A OD1 1 
ATOM   2424  N ND2 . ASN A 1 324 ? 156.304 124.156 168.250 1.00 58.45  ? 324 ASN A ND2 1 
ATOM   2425  N N   . VAL A 1 325 ? 153.961 126.632 171.238 1.00 65.66  ? 325 VAL A N   1 
ATOM   2426  C CA  . VAL A 1 325 ? 154.596 127.472 172.252 1.00 65.66  ? 325 VAL A CA  1 
ATOM   2427  C C   . VAL A 1 325 ? 155.664 126.646 172.956 1.00 65.66  ? 325 VAL A C   1 
ATOM   2428  O O   . VAL A 1 325 ? 155.369 125.535 173.412 1.00 65.66  ? 325 VAL A O   1 
ATOM   2429  C CB  . VAL A 1 325 ? 153.574 128.014 173.269 1.00 65.66  ? 325 VAL A CB  1 
ATOM   2430  C CG1 . VAL A 1 325 ? 154.227 129.029 174.193 1.00 65.66  ? 325 VAL A CG1 1 
ATOM   2431  C CG2 . VAL A 1 325 ? 152.388 128.632 172.550 1.00 65.66  ? 325 VAL A CG2 1 
ATOM   2432  N N   . PRO A 1 326 ? 156.898 127.134 173.059 1.00 69.74  ? 326 PRO A N   1 
ATOM   2433  C CA  . PRO A 1 326 ? 157.940 126.369 173.754 1.00 69.74  ? 326 PRO A CA  1 
ATOM   2434  C C   . PRO A 1 326 ? 157.661 126.248 175.244 1.00 69.74  ? 326 PRO A C   1 
ATOM   2435  O O   . PRO A 1 326 ? 157.048 127.120 175.863 1.00 69.74  ? 326 PRO A O   1 
ATOM   2436  C CB  . PRO A 1 326 ? 159.215 127.184 173.497 1.00 69.74  ? 326 PRO A CB  1 
ATOM   2437  C CG  . PRO A 1 326 ? 158.870 128.135 172.392 1.00 69.74  ? 326 PRO A CG  1 
ATOM   2438  C CD  . PRO A 1 326 ? 157.410 128.404 172.522 1.00 69.74  ? 326 PRO A CD  1 
ATOM   2439  N N   . GLU A 1 327 ? 158.127 125.144 175.818 1.00 75.31  ? 327 GLU A N   1 
ATOM   2440  C CA  . GLU A 1 327 ? 157.998 124.914 177.251 1.00 75.31  ? 327 GLU A CA  1 
ATOM   2441  C C   . GLU A 1 327 ? 158.946 125.813 178.036 1.00 75.31  ? 327 GLU A C   1 
ATOM   2442  O O   . GLU A 1 327 ? 160.142 125.541 178.122 1.00 75.31  ? 327 GLU A O   1 
ATOM   2443  C CB  . GLU A 1 327 ? 158.269 123.447 177.589 1.00 75.31  ? 327 GLU A CB  1 
ATOM   2444  C CG  . GLU A 1 327 ? 158.097 123.114 179.062 1.00 75.31  ? 327 GLU A CG  1 
ATOM   2445  C CD  . GLU A 1 327 ? 157.376 121.800 179.283 1.00 75.31  ? 327 GLU A CD  1 
ATOM   2446  O OE1 . GLU A 1 327 ? 157.202 121.044 178.305 1.00 75.31  ? 327 GLU A OE1 1 
ATOM   2447  O OE2 . GLU A 1 327 ? 156.983 121.524 180.435 1.00 75.31  ? 327 GLU A OE2 1 
ATOM   2448  N N   . ILE A 1 337 ? 155.055 123.176 188.816 1.00 83.09  ? 337 ILE A N   1 
ATOM   2449  C CA  . ILE A 1 337 ? 154.377 122.985 187.542 1.00 83.09  ? 337 ILE A CA  1 
ATOM   2450  C C   . ILE A 1 337 ? 153.644 124.262 187.143 1.00 83.09  ? 337 ILE A C   1 
ATOM   2451  O O   . ILE A 1 337 ? 153.267 125.063 187.998 1.00 83.09  ? 337 ILE A O   1 
ATOM   2452  C CB  . ILE A 1 337 ? 153.418 121.784 187.605 1.00 83.09  ? 337 ILE A CB  1 
ATOM   2453  C CG1 . ILE A 1 337 ? 152.370 121.987 188.700 1.00 83.09  ? 337 ILE A CG1 1 
ATOM   2454  C CG2 . ILE A 1 337 ? 154.191 120.500 187.850 1.00 83.09  ? 337 ILE A CG2 1 
ATOM   2455  C CD1 . ILE A 1 337 ? 151.291 120.932 188.703 1.00 83.09  ? 337 ILE A CD1 1 
ATOM   2456  N N   . ALA A 1 338 ? 153.446 124.449 185.840 1.00 80.12  ? 338 ALA A N   1 
ATOM   2457  C CA  . ALA A 1 338 ? 152.847 125.660 185.300 1.00 80.12  ? 338 ALA A CA  1 
ATOM   2458  C C   . ALA A 1 338 ? 151.662 125.300 184.412 1.00 80.12  ? 338 ALA A C   1 
ATOM   2459  O O   . ALA A 1 338 ? 151.405 124.130 184.119 1.00 80.12  ? 338 ALA A O   1 
ATOM   2460  C CB  . ALA A 1 338 ? 153.871 126.486 184.511 1.00 80.12  ? 338 ALA A CB  1 
ATOM   2461  N N   . GLY A 1 339 ? 150.939 126.329 183.983 1.00 77.86  ? 339 GLY A N   1 
ATOM   2462  C CA  . GLY A 1 339 ? 149.761 126.170 183.163 1.00 77.86  ? 339 GLY A CA  1 
ATOM   2463  C C   . GLY A 1 339 ? 150.016 126.472 181.701 1.00 77.86  ? 339 GLY A C   1 
ATOM   2464  O O   . GLY A 1 339 ? 151.143 126.381 181.202 1.00 77.86  ? 339 GLY A O   1 
ATOM   2465  N N   . PHE A 1 340 ? 148.943 126.845 181.002 1.00 74.47  ? 340 PHE A N   1 
ATOM   2466  C CA  . PHE A 1 340 ? 149.002 127.090 179.567 1.00 74.47  ? 340 PHE A CA  1 
ATOM   2467  C C   . PHE A 1 340 ? 149.427 128.509 179.212 1.00 74.47  ? 340 PHE A C   1 
ATOM   2468  O O   . PHE A 1 340 ? 149.600 128.802 178.025 1.00 74.47  ? 340 PHE A O   1 
ATOM   2469  C CB  . PHE A 1 340 ? 147.641 126.795 178.927 1.00 74.47  ? 340 PHE A CB  1 
ATOM   2470  C CG  . PHE A 1 340 ? 146.548 127.741 179.349 1.00 74.47  ? 340 PHE A CG  1 
ATOM   2471  C CD1 . PHE A 1 340 ? 145.797 127.489 180.484 1.00 74.47  ? 340 PHE A CD1 1 
ATOM   2472  C CD2 . PHE A 1 340 ? 146.263 128.874 178.604 1.00 74.47  ? 340 PHE A CD2 1 
ATOM   2473  C CE1 . PHE A 1 340 ? 144.793 128.350 180.872 1.00 74.47  ? 340 PHE A CE1 1 
ATOM   2474  C CE2 . PHE A 1 340 ? 145.261 129.741 178.989 1.00 74.47  ? 340 PHE A CE2 1 
ATOM   2475  C CZ  . PHE A 1 340 ? 144.524 129.478 180.124 1.00 74.47  ? 340 PHE A CZ  1 
ATOM   2476  N N   . ILE A 1 341 ? 149.598 129.391 180.193 1.00 76.88  ? 341 ILE A N   1 
ATOM   2477  C CA  . ILE A 1 341 ? 149.897 130.788 179.905 1.00 76.88  ? 341 ILE A CA  1 
ATOM   2478  C C   . ILE A 1 341 ? 151.336 130.910 179.419 1.00 76.88  ? 341 ILE A C   1 
ATOM   2479  O O   . ILE A 1 341 ? 152.280 130.848 180.215 1.00 76.88  ? 341 ILE A O   1 
ATOM   2480  C CB  . ILE A 1 341 ? 149.643 131.679 181.134 1.00 76.88  ? 341 ILE A CB  1 
ATOM   2481  C CG1 . ILE A 1 341 ? 148.247 131.411 181.703 1.00 76.88  ? 341 ILE A CG1 1 
ATOM   2482  C CG2 . ILE A 1 341 ? 149.813 133.147 180.776 1.00 76.88  ? 341 ILE A CG2 1 
ATOM   2483  C CD1 . ILE A 1 341 ? 147.146 132.227 181.061 1.00 76.88  ? 341 ILE A CD1 1 
ATOM   2484  N N   . GLU A 1 342 ? 151.502 131.080 178.105 1.00 77.35  ? 342 GLU A N   1 
ATOM   2485  C CA  . GLU A 1 342 ? 152.814 131.240 177.472 1.00 77.35  ? 342 GLU A CA  1 
ATOM   2486  C C   . GLU A 1 342 ? 153.738 130.062 177.778 1.00 77.35  ? 342 GLU A C   1 
ATOM   2487  O O   . GLU A 1 342 ? 154.943 130.230 177.968 1.00 77.35  ? 342 GLU A O   1 
ATOM   2488  C CB  . GLU A 1 342 ? 153.466 132.564 177.882 1.00 77.35  ? 342 GLU A CB  1 
ATOM   2489  C CG  . GLU A 1 342 ? 153.161 133.739 176.958 1.00 77.35  ? 342 GLU A CG  1 
ATOM   2490  C CD  . GLU A 1 342 ? 151.777 134.339 177.166 1.00 77.35  ? 342 GLU A CD  1 
ATOM   2491  O OE1 . GLU A 1 342 ? 151.587 135.518 176.802 1.00 77.35  ? 342 GLU A OE1 1 
ATOM   2492  O OE2 . GLU A 1 342 ? 150.881 133.644 177.691 1.00 77.35  ? 342 GLU A OE2 1 
ATOM   2493  N N   . ASN A 1 343 ? 153.172 128.857 177.819 1.00 75.02  ? 343 ASN A N   1 
ATOM   2494  C CA  . ASN A 1 343 ? 153.956 127.670 178.134 1.00 75.02  ? 343 ASN A CA  1 
ATOM   2495  C C   . ASN A 1 343 ? 153.253 126.441 177.578 1.00 75.02  ? 343 ASN A C   1 
ATOM   2496  O O   . ASN A 1 343 ? 152.069 126.226 177.853 1.00 75.02  ? 343 ASN A O   1 
ATOM   2497  C CB  . ASN A 1 343 ? 154.161 127.535 179.649 1.00 75.02  ? 343 ASN A CB  1 
ATOM   2498  C CG  . ASN A 1 343 ? 154.674 126.165 180.051 1.00 75.02  ? 343 ASN A CG  1 
ATOM   2499  O OD1 . ASN A 1 343 ? 155.797 125.789 179.719 1.00 75.02  ? 343 ASN A OD1 1 
ATOM   2500  N ND2 . ASN A 1 343 ? 153.851 125.412 180.772 1.00 75.02  ? 343 ASN A ND2 1 
ATOM   2501  N N   . GLY A 1 344 ? 153.982 125.644 176.802 1.00 73.11  ? 344 GLY A N   1 
ATOM   2502  C CA  . GLY A 1 344 ? 153.455 124.399 176.278 1.00 73.11  ? 344 GLY A CA  1 
ATOM   2503  C C   . GLY A 1 344 ? 154.043 123.191 176.978 1.00 73.11  ? 344 GLY A C   1 
ATOM   2504  O O   . GLY A 1 344 ? 155.072 123.303 177.648 1.00 73.11  ? 344 GLY A O   1 
ATOM   2505  N N   . TRP A 1 345 ? 153.406 122.034 176.836 1.00 74.36  ? 345 TRP A N   1 
ATOM   2506  C CA  . TRP A 1 345 ? 153.833 120.811 177.513 1.00 74.36  ? 345 TRP A CA  1 
ATOM   2507  C C   . TRP A 1 345 ? 154.419 119.857 176.477 1.00 74.36  ? 345 TRP A C   1 
ATOM   2508  O O   . TRP A 1 345 ? 153.681 119.159 175.775 1.00 74.36  ? 345 TRP A O   1 
ATOM   2509  C CB  . TRP A 1 345 ? 152.670 120.167 178.262 1.00 74.36  ? 345 TRP A CB  1 
ATOM   2510  C CG  . TRP A 1 345 ? 152.262 120.904 179.499 1.00 74.36  ? 345 TRP A CG  1 
ATOM   2511  C CD1 . TRP A 1 345 ? 152.917 121.943 180.089 1.00 74.36  ? 345 TRP A CD1 1 
ATOM   2512  C CD2 . TRP A 1 345 ? 151.105 120.651 180.303 1.00 74.36  ? 345 TRP A CD2 1 
ATOM   2513  N NE1 . TRP A 1 345 ? 152.237 122.357 181.208 1.00 74.36  ? 345 TRP A NE1 1 
ATOM   2514  C CE2 . TRP A 1 345 ? 151.121 121.578 181.362 1.00 74.36  ? 345 TRP A CE2 1 
ATOM   2515  C CE3 . TRP A 1 345 ? 150.055 119.732 180.228 1.00 74.36  ? 345 TRP A CE3 1 
ATOM   2516  C CZ2 . TRP A 1 345 ? 150.130 121.612 182.338 1.00 74.36  ? 345 TRP A CZ2 1 
ATOM   2517  C CZ3 . TRP A 1 345 ? 149.072 119.767 181.198 1.00 74.36  ? 345 TRP A CZ3 1 
ATOM   2518  C CH2 . TRP A 1 345 ? 149.117 120.700 182.239 1.00 74.36  ? 345 TRP A CH2 1 
ATOM   2519  N N   . GLU A 1 346 ? 155.750 119.827 176.386 1.00 76.59  ? 346 GLU A N   1 
ATOM   2520  C CA  . GLU A 1 346 ? 156.413 118.895 175.482 1.00 76.59  ? 346 GLU A CA  1 
ATOM   2521  C C   . GLU A 1 346 ? 156.302 117.451 175.950 1.00 76.59  ? 346 GLU A C   1 
ATOM   2522  O O   . GLU A 1 346 ? 156.480 116.537 175.140 1.00 76.59  ? 346 GLU A O   1 
ATOM   2523  C CB  . GLU A 1 346 ? 157.886 119.270 175.317 1.00 76.59  ? 346 GLU A CB  1 
ATOM   2524  C CG  . GLU A 1 346 ? 158.171 120.131 174.101 1.00 76.59  ? 346 GLU A CG  1 
ATOM   2525  C CD  . GLU A 1 346 ? 159.626 120.080 173.679 1.00 76.59  ? 346 GLU A CD  1 
ATOM   2526  O OE1 . GLU A 1 346 ? 160.389 119.286 174.268 1.00 76.59  ? 346 GLU A OE1 1 
ATOM   2527  O OE2 . GLU A 1 346 ? 160.006 120.836 172.760 1.00 76.59  ? 346 GLU A OE2 1 
ATOM   2528  N N   . GLY A 1 347 ? 156.007 117.225 177.226 1.00 78.15  ? 347 GLY A N   1 
ATOM   2529  C CA  . GLY A 1 347 ? 155.945 115.879 177.760 1.00 78.15  ? 347 GLY A CA  1 
ATOM   2530  C C   . GLY A 1 347 ? 154.571 115.246 177.686 1.00 78.15  ? 347 GLY A C   1 
ATOM   2531  O O   . GLY A 1 347 ? 154.304 114.252 178.367 1.00 78.15  ? 347 GLY A O   1 
ATOM   2532  N N   . MET A 1 348 ? 153.687 115.810 176.869 1.00 78.15  ? 348 MET A N   1 
ATOM   2533  C CA  . MET A 1 348 ? 152.324 115.314 176.721 1.00 78.15  ? 348 MET A CA  1 
ATOM   2534  C C   . MET A 1 348 ? 152.154 114.733 175.325 1.00 78.15  ? 348 MET A C   1 
ATOM   2535  O O   . MET A 1 348 ? 152.191 115.470 174.333 1.00 78.15  ? 348 MET A O   1 
ATOM   2536  C CB  . MET A 1 348 ? 151.305 116.425 176.969 1.00 78.15  ? 348 MET A CB  1 
ATOM   2537  C CG  . MET A 1 348 ? 149.864 115.979 176.816 1.00 78.15  ? 348 MET A CG  1 
ATOM   2538  S SD  . MET A 1 348 ? 148.744 116.848 177.926 1.00 78.15  ? 348 MET A SD  1 
ATOM   2539  C CE  . MET A 1 348 ? 148.151 118.150 176.853 1.00 78.15  ? 348 MET A CE  1 
ATOM   2540  N N   . ILE A 1 349 ? 151.965 113.417 175.251 1.00 79.46  ? 349 ILE A N   1 
ATOM   2541  C CA  . ILE A 1 349 ? 151.767 112.717 173.990 1.00 79.46  ? 349 ILE A CA  1 
ATOM   2542  C C   . ILE A 1 349 ? 150.468 111.929 173.954 1.00 79.46  ? 349 ILE A C   1 
ATOM   2543  O O   . ILE A 1 349 ? 150.282 111.106 173.053 1.00 79.46  ? 349 ILE A O   1 
ATOM   2544  C CB  . ILE A 1 349 ? 152.961 111.793 173.667 1.00 79.46  ? 349 ILE A CB  1 
ATOM   2545  C CG1 . ILE A 1 349 ? 153.361 110.966 174.894 1.00 79.46  ? 349 ILE A CG1 1 
ATOM   2546  C CG2 . ILE A 1 349 ? 154.142 112.608 173.164 1.00 79.46  ? 349 ILE A CG2 1 
ATOM   2547  C CD1 . ILE A 1 349 ? 152.626 109.648 175.031 1.00 79.46  ? 349 ILE A CD1 1 
ATOM   2548  N N   . ASP A 1 350 ? 149.565 112.152 174.905 1.00 78.85  ? 350 ASP A N   1 
ATOM   2549  C CA  . ASP A 1 350 ? 148.324 111.397 175.002 1.00 78.85  ? 350 ASP A CA  1 
ATOM   2550  C C   . ASP A 1 350 ? 147.106 112.185 174.541 1.00 78.85  ? 350 ASP A C   1 
ATOM   2551  O O   . ASP A 1 350 ? 146.007 111.624 174.487 1.00 78.85  ? 350 ASP A O   1 
ATOM   2552  C CB  . ASP A 1 350 ? 148.116 110.922 176.443 1.00 78.85  ? 350 ASP A CB  1 
ATOM   2553  C CG  . ASP A 1 350 ? 147.257 109.680 176.528 1.00 78.85  ? 350 ASP A CG  1 
ATOM   2554  O OD1 . ASP A 1 350 ? 147.307 108.859 175.589 1.00 78.85  ? 350 ASP A OD1 1 
ATOM   2555  O OD2 . ASP A 1 350 ? 146.533 109.527 177.533 1.00 78.85  ? 350 ASP A OD2 1 
ATOM   2556  N N   . GLY A 1 351 ? 147.270 113.459 174.210 1.00 73.63  ? 351 GLY A N   1 
ATOM   2557  C CA  . GLY A 1 351 ? 146.142 114.269 173.797 1.00 73.63  ? 351 GLY A CA  1 
ATOM   2558  C C   . GLY A 1 351 ? 146.592 115.673 173.467 1.00 73.63  ? 351 GLY A C   1 
ATOM   2559  O O   . GLY A 1 351 ? 147.789 115.962 173.401 1.00 73.63  ? 351 GLY A O   1 
ATOM   2560  N N   . TRP A 1 352 ? 145.611 116.549 173.258 1.00 66.29  ? 352 TRP A N   1 
ATOM   2561  C CA  . TRP A 1 352 ? 145.879 117.948 172.947 1.00 66.29  ? 352 TRP A CA  1 
ATOM   2562  C C   . TRP A 1 352 ? 145.765 118.857 174.162 1.00 66.29  ? 352 TRP A C   1 
ATOM   2563  O O   . TRP A 1 352 ? 146.612 119.732 174.353 1.00 66.29  ? 352 TRP A O   1 
ATOM   2564  C CB  . TRP A 1 352 ? 144.930 118.439 171.849 1.00 66.29  ? 352 TRP A CB  1 
ATOM   2565  C CG  . TRP A 1 352 ? 145.279 117.936 170.480 1.00 66.29  ? 352 TRP A CG  1 
ATOM   2566  C CD1 . TRP A 1 352 ? 146.054 116.854 170.175 1.00 66.29  ? 352 TRP A CD1 1 
ATOM   2567  C CD2 . TRP A 1 352 ? 144.862 118.494 169.228 1.00 66.29  ? 352 TRP A CD2 1 
ATOM   2568  N NE1 . TRP A 1 352 ? 146.147 116.706 168.814 1.00 66.29  ? 352 TRP A NE1 1 
ATOM   2569  C CE2 . TRP A 1 352 ? 145.424 117.700 168.209 1.00 66.29  ? 352 TRP A CE2 1 
ATOM   2570  C CE3 . TRP A 1 352 ? 144.070 119.588 168.871 1.00 66.29  ? 352 TRP A CE3 1 
ATOM   2571  C CZ2 . TRP A 1 352 ? 145.218 117.965 166.858 1.00 66.29  ? 352 TRP A CZ2 1 
ATOM   2572  C CZ3 . TRP A 1 352 ? 143.868 119.850 167.530 1.00 66.29  ? 352 TRP A CZ3 1 
ATOM   2573  C CH2 . TRP A 1 352 ? 144.439 119.042 166.539 1.00 66.29  ? 352 TRP A CH2 1 
ATOM   2574  N N   . TYR A 1 353 ? 144.738 118.669 174.985 1.00 66.71  ? 353 TYR A N   1 
ATOM   2575  C CA  . TYR A 1 353 ? 144.549 119.416 176.218 1.00 66.71  ? 353 TYR A CA  1 
ATOM   2576  C C   . TYR A 1 353 ? 144.587 118.450 177.394 1.00 66.71  ? 353 TYR A C   1 
ATOM   2577  O O   . TYR A 1 353 ? 144.218 117.280 177.261 1.00 66.71  ? 353 TYR A O   1 
ATOM   2578  C CB  . TYR A 1 353 ? 143.220 120.176 176.210 1.00 66.71  ? 353 TYR A CB  1 
ATOM   2579  C CG  . TYR A 1 353 ? 142.994 121.008 174.969 1.00 66.71  ? 353 TYR A CG  1 
ATOM   2580  C CD1 . TYR A 1 353 ? 143.458 122.313 174.892 1.00 66.71  ? 353 TYR A CD1 1 
ATOM   2581  C CD2 . TYR A 1 353 ? 142.319 120.486 173.874 1.00 66.71  ? 353 TYR A CD2 1 
ATOM   2582  C CE1 . TYR A 1 353 ? 143.254 123.074 173.761 1.00 66.71  ? 353 TYR A CE1 1 
ATOM   2583  C CE2 . TYR A 1 353 ? 142.111 121.241 172.739 1.00 66.71  ? 353 TYR A CE2 1 
ATOM   2584  C CZ  . TYR A 1 353 ? 142.582 122.534 172.688 1.00 66.71  ? 353 TYR A CZ  1 
ATOM   2585  O OH  . TYR A 1 353 ? 142.377 123.289 171.560 1.00 66.71  ? 353 TYR A OH  1 
ATOM   2586  N N   . GLY A 1 354 ? 145.034 118.935 178.548 1.00 72.74  ? 354 GLY A N   1 
ATOM   2587  C CA  . GLY A 1 354 ? 145.151 118.027 179.673 1.00 72.74  ? 354 GLY A CA  1 
ATOM   2588  C C   . GLY A 1 354 ? 145.351 118.735 180.995 1.00 72.74  ? 354 GLY A C   1 
ATOM   2589  O O   . GLY A 1 354 ? 145.515 119.958 181.064 1.00 72.74  ? 354 GLY A O   1 
ATOM   2590  N N   . PHE A 1 355 ? 145.345 117.921 182.048 1.00 77.56  ? 355 PHE A N   1 
ATOM   2591  C CA  . PHE A 1 355 ? 145.509 118.346 183.428 1.00 77.56  ? 355 PHE A CA  1 
ATOM   2592  C C   . PHE A 1 355 ? 146.826 117.820 183.983 1.00 77.56  ? 355 PHE A C   1 
ATOM   2593  O O   . PHE A 1 355 ? 147.302 116.747 183.600 1.00 77.56  ? 355 PHE A O   1 
ATOM   2594  C CB  . PHE A 1 355 ? 144.376 117.825 184.322 1.00 77.56  ? 355 PHE A CB  1 
ATOM   2595  C CG  . PHE A 1 355 ? 143.002 118.267 183.910 1.00 77.56  ? 355 PHE A CG  1 
ATOM   2596  C CD1 . PHE A 1 355 ? 142.279 117.546 182.975 1.00 77.56  ? 355 PHE A CD1 1 
ATOM   2597  C CD2 . PHE A 1 355 ? 142.417 119.381 184.487 1.00 77.56  ? 355 PHE A CD2 1 
ATOM   2598  C CE1 . PHE A 1 355 ? 141.008 117.941 182.607 1.00 77.56  ? 355 PHE A CE1 1 
ATOM   2599  C CE2 . PHE A 1 355 ? 141.147 119.781 184.124 1.00 77.56  ? 355 PHE A CE2 1 
ATOM   2600  C CZ  . PHE A 1 355 ? 140.442 119.060 183.183 1.00 77.56  ? 355 PHE A CZ  1 
ATOM   2601  N N   . ARG A 1 356 ? 147.402 118.584 184.904 1.00 80.20  ? 356 ARG A N   1 
ATOM   2602  C CA  . ARG A 1 356 ? 148.512 118.135 185.729 1.00 80.20  ? 356 ARG A CA  1 
ATOM   2603  C C   . ARG A 1 356 ? 148.182 118.468 187.175 1.00 80.20  ? 356 ARG A C   1 
ATOM   2604  O O   . ARG A 1 356 ? 147.511 119.465 187.447 1.00 80.20  ? 356 ARG A O   1 
ATOM   2605  C CB  . ARG A 1 356 ? 149.828 118.800 185.316 1.00 80.20  ? 356 ARG A CB  1 
ATOM   2606  C CG  . ARG A 1 356 ? 150.568 118.076 184.206 1.00 80.20  ? 356 ARG A CG  1 
ATOM   2607  C CD  . ARG A 1 356 ? 151.908 118.732 183.924 1.00 80.20  ? 356 ARG A CD  1 
ATOM   2608  N NE  . ARG A 1 356 ? 152.578 118.135 182.776 1.00 80.20  ? 356 ARG A NE  1 
ATOM   2609  C CZ  . ARG A 1 356 ? 153.691 118.604 182.230 1.00 80.20  ? 356 ARG A CZ  1 
ATOM   2610  N NH1 . ARG A 1 356 ? 154.292 119.683 182.704 1.00 80.20  ? 356 ARG A NH1 1 
ATOM   2611  N NH2 . ARG A 1 356 ? 154.212 117.976 181.181 1.00 80.20  ? 356 ARG A NH2 1 
ATOM   2612  N N   . HIS A 1 357 ? 148.630 117.630 188.104 1.00 87.51  ? 357 HIS A N   1 
ATOM   2613  C CA  . HIS A 1 357 ? 148.361 117.893 189.509 1.00 87.51  ? 357 HIS A CA  1 
ATOM   2614  C C   . HIS A 1 357 ? 149.601 117.627 190.346 1.00 87.51  ? 357 HIS A C   1 
ATOM   2615  O O   . HIS A 1 357 ? 150.342 116.673 190.100 1.00 87.51  ? 357 HIS A O   1 
ATOM   2616  C CB  . HIS A 1 357 ? 147.177 117.064 190.031 1.00 87.51  ? 357 HIS A CB  1 
ATOM   2617  C CG  . HIS A 1 357 ? 147.406 115.585 190.011 1.00 87.51  ? 357 HIS A CG  1 
ATOM   2618  N ND1 . HIS A 1 357 ? 146.982 114.781 188.976 1.00 87.51  ? 357 HIS A ND1 1 
ATOM   2619  C CD2 . HIS A 1 357 ? 147.996 114.762 190.910 1.00 87.51  ? 357 HIS A CD2 1 
ATOM   2620  C CE1 . HIS A 1 357 ? 147.308 113.527 189.233 1.00 87.51  ? 357 HIS A CE1 1 
ATOM   2621  N NE2 . HIS A 1 357 ? 147.925 113.488 190.400 1.00 87.51  ? 357 HIS A NE2 1 
ATOM   2622  N N   . GLN A 1 358 ? 149.815 118.495 191.330 1.00 91.42  ? 358 GLN A N   1 
ATOM   2623  C CA  . GLN A 1 358 ? 150.905 118.390 192.287 1.00 91.42  ? 358 GLN A CA  1 
ATOM   2624  C C   . GLN A 1 358 ? 150.304 118.199 193.670 1.00 91.42  ? 358 GLN A C   1 
ATOM   2625  O O   . GLN A 1 358 ? 149.446 118.985 194.094 1.00 91.42  ? 358 GLN A O   1 
ATOM   2626  C CB  . GLN A 1 358 ? 151.794 119.634 192.248 1.00 91.42  ? 358 GLN A CB  1 
ATOM   2627  C CG  . GLN A 1 358 ? 153.203 119.414 192.760 1.00 91.42  ? 358 GLN A CG  1 
ATOM   2628  C CD  . GLN A 1 358 ? 153.976 120.711 192.886 1.00 91.42  ? 358 GLN A CD  1 
ATOM   2629  O OE1 . GLN A 1 358 ? 153.549 121.635 193.579 1.00 91.42  ? 358 GLN A OE1 1 
ATOM   2630  N NE2 . GLN A 1 358 ? 155.115 120.790 192.210 1.00 91.42  ? 358 GLN A NE2 1 
ATOM   2631  N N   . ASN A 1 359 ? 150.770 117.171 194.374 1.00 97.28  ? 359 ASN A N   1 
ATOM   2632  C CA  . ASN A 1 359 ? 150.065 116.647 195.535 1.00 97.28  ? 359 ASN A CA  1 
ATOM   2633  C C   . ASN A 1 359 ? 151.079 116.039 196.496 1.00 97.28  ? 359 ASN A C   1 
ATOM   2634  O O   . ASN A 1 359 ? 152.285 116.020 196.231 1.00 97.28  ? 359 ASN A O   1 
ATOM   2635  C CB  . ASN A 1 359 ? 149.025 115.615 195.099 1.00 97.28  ? 359 ASN A CB  1 
ATOM   2636  C CG  . ASN A 1 359 ? 147.853 115.538 196.038 1.00 97.28  ? 359 ASN A CG  1 
ATOM   2637  O OD1 . ASN A 1 359 ? 147.689 116.379 196.920 1.00 97.28  ? 359 ASN A OD1 1 
ATOM   2638  N ND2 . ASN A 1 359 ? 147.031 114.516 195.861 1.00 97.28  ? 359 ASN A ND2 1 
ATOM   2639  N N   . SER A 1 360 ? 150.573 115.541 197.627 1.00 98.86  ? 360 SER A N   1 
ATOM   2640  C CA  . SER A 1 360 ? 151.433 114.862 198.593 1.00 98.86  ? 360 SER A CA  1 
ATOM   2641  C C   . SER A 1 360 ? 151.978 113.555 198.029 1.00 98.86  ? 360 SER A C   1 
ATOM   2642  O O   . SER A 1 360 ? 153.151 113.225 198.239 1.00 98.86  ? 360 SER A O   1 
ATOM   2643  C CB  . SER A 1 360 ? 150.666 114.611 199.891 1.00 98.86  ? 360 SER A CB  1 
ATOM   2644  O OG  . SER A 1 360 ? 149.618 113.679 199.691 1.00 98.86  ? 360 SER A OG  1 
ATOM   2645  N N   . GLU A 1 361 ? 151.139 112.794 197.320 1.00 99.48  ? 361 GLU A N   1 
ATOM   2646  C CA  . GLU A 1 361 ? 151.607 111.560 196.695 1.00 99.48  ? 361 GLU A CA  1 
ATOM   2647  C C   . GLU A 1 361 ? 152.667 111.847 195.640 1.00 99.48  ? 361 GLU A C   1 
ATOM   2648  O O   . GLU A 1 361 ? 153.654 111.112 195.523 1.00 99.48  ? 361 GLU A O   1 
ATOM   2649  C CB  . GLU A 1 361 ? 150.432 110.803 196.078 1.00 99.48  ? 361 GLU A CB  1 
ATOM   2650  C CG  . GLU A 1 361 ? 149.683 109.909 197.046 1.00 99.48  ? 361 GLU A CG  1 
ATOM   2651  C CD  . GLU A 1 361 ? 148.183 109.974 196.844 1.00 99.48  ? 361 GLU A CD  1 
ATOM   2652  O OE1 . GLU A 1 361 ? 147.675 111.078 196.556 1.00 99.48  ? 361 GLU A OE1 1 
ATOM   2653  O OE2 . GLU A 1 361 ? 147.517 108.925 196.962 1.00 99.48  ? 361 GLU A OE2 1 
ATOM   2654  N N   . GLY A 1 362 ? 152.478 112.898 194.865 1.00 96.32  ? 362 GLY A N   1 
ATOM   2655  C CA  . GLY A 1 362 ? 153.440 113.273 193.850 1.00 96.32  ? 362 GLY A CA  1 
ATOM   2656  C C   . GLY A 1 362 ? 152.735 113.865 192.648 1.00 96.32  ? 362 GLY A C   1 
ATOM   2657  O O   . GLY A 1 362 ? 151.512 113.962 192.598 1.00 96.32  ? 362 GLY A O   1 
ATOM   2658  N N   . THR A 1 363 ? 153.546 114.264 191.674 1.00 92.35  ? 363 THR A N   1 
ATOM   2659  C CA  . THR A 1 363 ? 153.015 114.833 190.445 1.00 92.35  ? 363 THR A CA  1 
ATOM   2660  C C   . THR A 1 363 ? 152.308 113.767 189.617 1.00 92.35  ? 363 THR A C   1 
ATOM   2661  O O   . THR A 1 363 ? 152.698 112.596 189.613 1.00 92.35  ? 363 THR A O   1 
ATOM   2662  C CB  . THR A 1 363 ? 154.134 115.472 189.624 1.00 92.35  ? 363 THR A CB  1 
ATOM   2663  O OG1 . THR A 1 363 ? 155.007 114.449 189.129 1.00 92.35  ? 363 THR A OG1 1 
ATOM   2664  C CG2 . THR A 1 363 ? 154.932 116.447 190.476 1.00 92.35  ? 363 THR A CG2 1 
ATOM   2665  N N   . GLY A 1 364 ? 151.257 114.184 188.917 1.00 87.02  ? 364 GLY A N   1 
ATOM   2666  C CA  . GLY A 1 364 ? 150.537 113.301 188.019 1.00 87.02  ? 364 GLY A CA  1 
ATOM   2667  C C   . GLY A 1 364 ? 150.010 114.087 186.838 1.00 87.02  ? 364 GLY A C   1 
ATOM   2668  O O   . GLY A 1 364 ? 149.873 115.313 186.896 1.00 87.02  ? 364 GLY A O   1 
ATOM   2669  N N   . GLN A 1 365 ? 149.706 113.366 185.761 1.00 81.75  ? 365 GLN A N   1 
ATOM   2670  C CA  . GLN A 1 365 ? 149.296 113.990 184.511 1.00 81.75  ? 365 GLN A CA  1 
ATOM   2671  C C   . GLN A 1 365 ? 148.187 113.171 183.866 1.00 81.75  ? 365 GLN A C   1 
ATOM   2672  O O   . GLN A 1 365 ? 148.129 111.949 184.018 1.00 81.75  ? 365 GLN A O   1 
ATOM   2673  C CB  . GLN A 1 365 ? 150.487 114.130 183.551 1.00 81.75  ? 365 GLN A CB  1 
ATOM   2674  C CG  . GLN A 1 365 ? 150.195 114.898 182.275 1.00 81.75  ? 365 GLN A CG  1 
ATOM   2675  C CD  . GLN A 1 365 ? 151.457 115.277 181.524 1.00 81.75  ? 365 GLN A CD  1 
ATOM   2676  O OE1 . GLN A 1 365 ? 152.561 115.204 182.063 1.00 81.75  ? 365 GLN A OE1 1 
ATOM   2677  N NE2 . GLN A 1 365 ? 151.300 115.682 180.270 1.00 81.75  ? 365 GLN A NE2 1 
ATOM   2678  N N   . ALA A 1 366 ? 147.306 113.858 183.144 1.00 78.39  ? 366 ALA A N   1 
ATOM   2679  C CA  . ALA A 1 366 ? 146.230 113.199 182.416 1.00 78.39  ? 366 ALA A CA  1 
ATOM   2680  C C   . ALA A 1 366 ? 145.791 114.110 181.281 1.00 78.39  ? 366 ALA A C   1 
ATOM   2681  O O   . ALA A 1 366 ? 146.157 115.285 181.226 1.00 78.39  ? 366 ALA A O   1 
ATOM   2682  C CB  . ALA A 1 366 ? 145.053 112.857 183.334 1.00 78.39  ? 366 ALA A CB  1 
ATOM   2683  N N   . ALA A 1 367 ? 144.987 113.557 180.380 1.00 74.41  ? 367 ALA A N   1 
ATOM   2684  C CA  . ALA A 1 367 ? 144.516 114.274 179.207 1.00 74.41  ? 367 ALA A CA  1 
ATOM   2685  C C   . ALA A 1 367 ? 142.997 114.388 179.231 1.00 74.41  ? 367 ALA A C   1 
ATOM   2686  O O   . ALA A 1 367 ? 142.301 113.595 179.870 1.00 74.41  ? 367 ALA A O   1 
ATOM   2687  C CB  . ALA A 1 367 ? 144.969 113.585 177.915 1.00 74.41  ? 367 ALA A CB  1 
ATOM   2688  N N   . ASP A 1 368 ? 142.491 115.394 178.524 1.00 72.37  ? 368 ASP A N   1 
ATOM   2689  C CA  . ASP A 1 368 ? 141.062 115.654 178.416 1.00 72.37  ? 368 ASP A CA  1 
ATOM   2690  C C   . ASP A 1 368 ? 140.594 115.199 177.041 1.00 72.37  ? 368 ASP A C   1 
ATOM   2691  O O   . ASP A 1 368 ? 141.100 115.677 176.020 1.00 72.37  ? 368 ASP A O   1 
ATOM   2692  C CB  . ASP A 1 368 ? 140.760 117.137 178.631 1.00 72.37  ? 368 ASP A CB  1 
ATOM   2693  C CG  . ASP A 1 368 ? 139.308 117.393 178.982 1.00 72.37  ? 368 ASP A CG  1 
ATOM   2694  O OD1 . ASP A 1 368 ? 138.419 116.840 178.304 1.00 72.37  ? 368 ASP A OD1 1 
ATOM   2695  O OD2 . ASP A 1 368 ? 139.055 118.150 179.941 1.00 72.37  ? 368 ASP A OD2 1 
ATOM   2696  N N   . LEU A 1 369 ? 139.628 114.280 177.017 1.00 70.42  ? 369 LEU A N   1 
ATOM   2697  C CA  . LEU A 1 369 ? 139.191 113.700 175.753 1.00 70.42  ? 369 LEU A CA  1 
ATOM   2698  C C   . LEU A 1 369 ? 138.131 114.544 175.057 1.00 70.42  ? 369 LEU A C   1 
ATOM   2699  O O   . LEU A 1 369 ? 138.121 114.614 173.825 1.00 70.42  ? 369 LEU A O   1 
ATOM   2700  C CB  . LEU A 1 369 ? 138.662 112.282 175.980 1.00 70.42  ? 369 LEU A CB  1 
ATOM   2701  C CG  . LEU A 1 369 ? 139.529 111.355 176.835 1.00 70.42  ? 369 LEU A CG  1 
ATOM   2702  C CD1 . LEU A 1 369 ? 138.925 109.961 176.899 1.00 70.42  ? 369 LEU A CD1 1 
ATOM   2703  C CD2 . LEU A 1 369 ? 140.954 111.300 176.304 1.00 70.42  ? 369 LEU A CD2 1 
ATOM   2704  N N   . LYS A 1 370 ? 137.240 115.187 175.815 1.00 69.61  ? 370 LYS A N   1 
ATOM   2705  C CA  . LYS A 1 370 ? 136.119 115.894 175.200 1.00 69.61  ? 370 LYS A CA  1 
ATOM   2706  C C   . LYS A 1 370 ? 136.587 117.110 174.405 1.00 69.61  ? 370 LYS A C   1 
ATOM   2707  O O   . LYS A 1 370 ? 136.178 117.305 173.254 1.00 69.61  ? 370 LYS A O   1 
ATOM   2708  C CB  . LYS A 1 370 ? 135.109 116.303 176.271 1.00 69.61  ? 370 LYS A CB  1 
ATOM   2709  C CG  . LYS A 1 370 ? 134.493 115.127 177.011 1.00 69.61  ? 370 LYS A CG  1 
ATOM   2710  C CD  . LYS A 1 370 ? 133.506 115.587 178.071 1.00 69.61  ? 370 LYS A CD  1 
ATOM   2711  C CE  . LYS A 1 370 ? 132.864 114.404 178.774 1.00 69.61  ? 370 LYS A CE  1 
ATOM   2712  N NZ  . LYS A 1 370 ? 131.872 114.833 179.799 1.00 69.61  ? 370 LYS A NZ  1 
ATOM   2713  N N   . SER A 1 371 ? 137.438 117.946 175.006 1.00 68.16  ? 371 SER A N   1 
ATOM   2714  C CA  . SER A 1 371 ? 137.915 119.137 174.307 1.00 68.16  ? 371 SER A CA  1 
ATOM   2715  C C   . SER A 1 371 ? 138.792 118.766 173.117 1.00 68.16  ? 371 SER A C   1 
ATOM   2716  O O   . SER A 1 371 ? 138.703 119.390 172.051 1.00 68.16  ? 371 SER A O   1 
ATOM   2717  C CB  . SER A 1 371 ? 138.670 120.047 175.276 1.00 68.16  ? 371 SER A CB  1 
ATOM   2718  O OG  . SER A 1 371 ? 139.696 119.340 175.950 1.00 68.16  ? 371 SER A OG  1 
ATOM   2719  N N   . THR A 1 372 ? 139.640 117.749 173.281 1.00 66.49  ? 372 THR A N   1 
ATOM   2720  C CA  . THR A 1 372 ? 140.455 117.267 172.171 1.00 66.49  ? 372 THR A CA  1 
ATOM   2721  C C   . THR A 1 372 ? 139.579 116.788 171.020 1.00 66.49  ? 372 THR A C   1 
ATOM   2722  O O   . THR A 1 372 ? 139.835 117.104 169.852 1.00 66.49  ? 372 THR A O   1 
ATOM   2723  C CB  . THR A 1 372 ? 141.372 116.140 172.650 1.00 66.49  ? 372 THR A CB  1 
ATOM   2724  O OG1 . THR A 1 372 ? 142.212 116.619 173.707 1.00 66.49  ? 372 THR A OG1 1 
ATOM   2725  C CG2 . THR A 1 372 ? 142.239 115.636 171.513 1.00 66.49  ? 372 THR A CG2 1 
ATOM   2726  N N   . GLN A 1 373 ? 138.530 116.027 171.339 1.00 66.09  ? 373 GLN A N   1 
ATOM   2727  C CA  . GLN A 1 373 ? 137.632 115.523 170.307 1.00 66.09  ? 373 GLN A CA  1 
ATOM   2728  C C   . GLN A 1 373 ? 136.903 116.661 169.609 1.00 66.09  ? 373 GLN A C   1 
ATOM   2729  O O   . GLN A 1 373 ? 136.752 116.649 168.383 1.00 66.09  ? 373 GLN A O   1 
ATOM   2730  C CB  . GLN A 1 373 ? 136.632 114.542 170.920 1.00 66.09  ? 373 GLN A CB  1 
ATOM   2731  C CG  . GLN A 1 373 ? 135.927 113.641 169.920 1.00 66.09  ? 373 GLN A CG  1 
ATOM   2732  C CD  . GLN A 1 373 ? 136.889 112.845 169.055 1.00 66.09  ? 373 GLN A CD  1 
ATOM   2733  O OE1 . GLN A 1 373 ? 136.632 112.617 167.875 1.00 66.09  ? 373 GLN A OE1 1 
ATOM   2734  N NE2 . GLN A 1 373 ? 137.995 112.405 169.644 1.00 66.09  ? 373 GLN A NE2 1 
ATOM   2735  N N   . ALA A 1 374 ? 136.441 117.653 170.372 1.00 63.52  ? 374 ALA A N   1 
ATOM   2736  C CA  . ALA A 1 374 ? 135.764 118.792 169.762 1.00 63.52  ? 374 ALA A CA  1 
ATOM   2737  C C   . ALA A 1 374 ? 136.690 119.537 168.810 1.00 63.52  ? 374 ALA A C   1 
ATOM   2738  O O   . ALA A 1 374 ? 136.300 119.870 167.683 1.00 63.52  ? 374 ALA A O   1 
ATOM   2739  C CB  . ALA A 1 374 ? 135.235 119.731 170.845 1.00 63.52  ? 374 ALA A CB  1 
ATOM   2740  N N   . ALA A 1 375 ? 137.933 119.782 169.236 1.00 62.18  ? 375 ALA A N   1 
ATOM   2741  C CA  . ALA A 1 375 ? 138.887 120.477 168.377 1.00 62.18  ? 375 ALA A CA  1 
ATOM   2742  C C   . ALA A 1 375 ? 139.179 119.679 167.112 1.00 62.18  ? 375 ALA A C   1 
ATOM   2743  O O   . ALA A 1 375 ? 139.221 120.241 166.011 1.00 62.18  ? 375 ALA A O   1 
ATOM   2744  C CB  . ALA A 1 375 ? 140.178 120.756 169.145 1.00 62.18  ? 375 ALA A CB  1 
ATOM   2745  N N   . ILE A 1 376 ? 139.376 118.365 167.248 1.00 62.28  ? 376 ILE A N   1 
ATOM   2746  C CA  . ILE A 1 376 ? 139.704 117.540 166.088 1.00 62.28  ? 376 ILE A CA  1 
ATOM   2747  C C   . ILE A 1 376 ? 138.538 117.500 165.106 1.00 62.28  ? 376 ILE A C   1 
ATOM   2748  O O   . ILE A 1 376 ? 138.725 117.646 163.893 1.00 62.28  ? 376 ILE A O   1 
ATOM   2749  C CB  . ILE A 1 376 ? 140.124 116.129 166.536 1.00 62.28  ? 376 ILE A CB  1 
ATOM   2750  C CG1 . ILE A 1 376 ? 141.622 116.097 166.837 1.00 62.28  ? 376 ILE A CG1 1 
ATOM   2751  C CG2 . ILE A 1 376 ? 139.772 115.097 165.477 1.00 62.28  ? 376 ILE A CG2 1 
ATOM   2752  C CD1 . ILE A 1 376 ? 142.004 115.118 167.915 1.00 62.28  ? 376 ILE A CD1 1 
ATOM   2753  N N   . ASP A 1 377 ? 137.316 117.312 165.611 1.00 63.11  ? 377 ASP A N   1 
ATOM   2754  C CA  . ASP A 1 377 ? 136.160 117.268 164.722 1.00 63.11  ? 377 ASP A CA  1 
ATOM   2755  C C   . ASP A 1 377 ? 135.882 118.619 164.077 1.00 63.11  ? 377 ASP A C   1 
ATOM   2756  O O   . ASP A 1 377 ? 135.335 118.669 162.970 1.00 63.11  ? 377 ASP A O   1 
ATOM   2757  C CB  . ASP A 1 377 ? 134.928 116.764 165.472 1.00 63.11  ? 377 ASP A CB  1 
ATOM   2758  C CG  . ASP A 1 377 ? 135.031 115.295 165.834 1.00 63.11  ? 377 ASP A CG  1 
ATOM   2759  O OD1 . ASP A 1 377 ? 135.999 114.911 166.519 1.00 63.11  ? 377 ASP A OD1 1 
ATOM   2760  O OD2 . ASP A 1 377 ? 134.154 114.516 165.405 1.00 63.11  ? 377 ASP A OD2 1 
ATOM   2761  N N   . GLN A 1 378 ? 136.235 119.720 164.742 1.00 58.55  ? 378 GLN A N   1 
ATOM   2762  C CA  . GLN A 1 378 ? 136.140 121.013 164.076 1.00 58.55  ? 378 GLN A CA  1 
ATOM   2763  C C   . GLN A 1 378 ? 137.182 121.142 162.971 1.00 58.55  ? 378 GLN A C   1 
ATOM   2764  O O   . GLN A 1 378 ? 136.877 121.629 161.877 1.00 58.55  ? 378 GLN A O   1 
ATOM   2765  C CB  . GLN A 1 378 ? 136.292 122.143 165.092 1.00 58.55  ? 378 GLN A CB  1 
ATOM   2766  C CG  . GLN A 1 378 ? 134.984 122.599 165.703 1.00 58.55  ? 378 GLN A CG  1 
ATOM   2767  C CD  . GLN A 1 378 ? 135.158 123.186 167.087 1.00 58.55  ? 378 GLN A CD  1 
ATOM   2768  O OE1 . GLN A 1 378 ? 135.206 124.403 167.254 1.00 58.55  ? 378 GLN A OE1 1 
ATOM   2769  N NE2 . GLN A 1 378 ? 135.256 122.321 168.089 1.00 58.55  ? 378 GLN A NE2 1 
ATOM   2770  N N   . ILE A 1 379 ? 138.415 120.705 163.238 1.00 57.40  ? 379 ILE A N   1 
ATOM   2771  C CA  . ILE A 1 379 ? 139.499 120.887 162.277 1.00 57.40  ? 379 ILE A CA  1 
ATOM   2772  C C   . ILE A 1 379 ? 139.316 119.979 161.064 1.00 57.40  ? 379 ILE A C   1 
ATOM   2773  O O   . ILE A 1 379 ? 139.568 120.387 159.924 1.00 57.40  ? 379 ILE A O   1 
ATOM   2774  C CB  . ILE A 1 379 ? 140.857 120.660 162.967 1.00 57.40  ? 379 ILE A CB  1 
ATOM   2775  C CG1 . ILE A 1 379 ? 141.215 121.868 163.836 1.00 57.40  ? 379 ILE A CG1 1 
ATOM   2776  C CG2 . ILE A 1 379 ? 141.950 120.396 161.946 1.00 57.40  ? 379 ILE A CG2 1 
ATOM   2777  C CD1 . ILE A 1 379 ? 142.474 121.688 164.649 1.00 57.40  ? 379 ILE A CD1 1 
ATOM   2778  N N   . ASN A 1 380 ? 138.874 118.745 161.283 1.00 58.47  ? 380 ASN A N   1 
ATOM   2779  C CA  . ASN A 1 380 ? 138.773 117.783 160.192 1.00 58.47  ? 380 ASN A CA  1 
ATOM   2780  C C   . ASN A 1 380 ? 137.666 118.176 159.220 1.00 58.47  ? 380 ASN A C   1 
ATOM   2781  O O   . ASN A 1 380 ? 136.551 118.507 159.632 1.00 58.47  ? 380 ASN A O   1 
ATOM   2782  C CB  . ASN A 1 380 ? 138.517 116.383 160.746 1.00 58.47  ? 380 ASN A CB  1 
ATOM   2783  C CG  . ASN A 1 380 ? 139.798 115.615 161.001 1.00 58.47  ? 380 ASN A CG  1 
ATOM   2784  O OD1 . ASN A 1 380 ? 140.892 116.097 160.710 1.00 58.47  ? 380 ASN A OD1 1 
ATOM   2785  N ND2 . ASN A 1 380 ? 139.668 114.412 161.547 1.00 58.47  ? 380 ASN A ND2 1 
ATOM   2786  N N   . GLY A 1 381 ? 137.978 118.135 157.926 1.00 54.26  ? 381 GLY A N   1 
ATOM   2787  C CA  . GLY A 1 381 ? 136.998 118.426 156.897 1.00 54.26  ? 381 GLY A CA  1 
ATOM   2788  C C   . GLY A 1 381 ? 136.639 119.883 156.726 1.00 54.26  ? 381 GLY A C   1 
ATOM   2789  O O   . GLY A 1 381 ? 135.538 120.183 156.256 1.00 54.26  ? 381 GLY A O   1 
ATOM   2790  N N   . LYS A 1 382 ? 137.533 120.804 157.091 1.00 50.65  ? 382 LYS A N   1 
ATOM   2791  C CA  . LYS A 1 382 ? 137.209 122.225 157.013 1.00 50.65  ? 382 LYS A CA  1 
ATOM   2792  C C   . LYS A 1 382 ? 137.084 122.695 155.567 1.00 50.65  ? 382 LYS A C   1 
ATOM   2793  O O   . LYS A 1 382 ? 136.127 123.393 155.213 1.00 50.65  ? 382 LYS A O   1 
ATOM   2794  C CB  . LYS A 1 382 ? 138.267 123.044 157.753 1.00 50.65  ? 382 LYS A CB  1 
ATOM   2795  C CG  . LYS A 1 382 ? 138.047 123.118 159.250 1.00 50.65  ? 382 LYS A CG  1 
ATOM   2796  C CD  . LYS A 1 382 ? 137.766 124.537 159.705 1.00 50.65  ? 382 LYS A CD  1 
ATOM   2797  C CE  . LYS A 1 382 ? 139.043 125.342 159.831 1.00 50.65  ? 382 LYS A CE  1 
ATOM   2798  N NZ  . LYS A 1 382 ? 138.775 126.722 160.314 1.00 50.65  ? 382 LYS A NZ  1 
ATOM   2799  N N   . LEU A 1 383 ? 138.039 122.319 154.715 1.00 48.94  ? 383 LEU A N   1 
ATOM   2800  C CA  . LEU A 1 383 ? 138.074 122.849 153.357 1.00 48.94  ? 383 LEU A CA  1 
ATOM   2801  C C   . LEU A 1 383 ? 136.943 122.317 152.485 1.00 48.94  ? 383 LEU A C   1 
ATOM   2802  O O   . LEU A 1 383 ? 136.576 122.973 151.506 1.00 48.94  ? 383 LEU A O   1 
ATOM   2803  C CB  . LEU A 1 383 ? 139.421 122.538 152.706 1.00 48.94  ? 383 LEU A CB  1 
ATOM   2804  C CG  . LEU A 1 383 ? 139.925 123.579 151.707 1.00 48.94  ? 383 LEU A CG  1 
ATOM   2805  C CD1 . LEU A 1 383 ? 140.131 124.921 152.388 1.00 48.94  ? 383 LEU A CD1 1 
ATOM   2806  C CD2 . LEU A 1 383 ? 141.203 123.108 151.047 1.00 48.94  ? 383 LEU A CD2 1 
ATOM   2807  N N   . ASN A 1 384 ? 136.384 121.152 152.813 1.00 51.33  ? 384 ASN A N   1 
ATOM   2808  C CA  . ASN A 1 384 ? 135.279 120.613 152.030 1.00 51.33  ? 384 ASN A CA  1 
ATOM   2809  C C   . ASN A 1 384 ? 133.996 121.416 152.200 1.00 51.33  ? 384 ASN A C   1 
ATOM   2810  O O   . ASN A 1 384 ? 133.090 121.293 151.368 1.00 51.33  ? 384 ASN A O   1 
ATOM   2811  C CB  . ASN A 1 384 ? 135.030 119.153 152.407 1.00 51.33  ? 384 ASN A CB  1 
ATOM   2812  C CG  . ASN A 1 384 ? 136.228 118.267 152.131 1.00 51.33  ? 384 ASN A CG  1 
ATOM   2813  O OD1 . ASN A 1 384 ? 136.943 118.459 151.148 1.00 51.33  ? 384 ASN A OD1 1 
ATOM   2814  N ND2 . ASN A 1 384 ? 136.454 117.290 153.000 1.00 51.33  ? 384 ASN A ND2 1 
ATOM   2815  N N   . ARG A 1 385 ? 133.893 122.228 153.254 1.00 49.99  ? 385 ARG A N   1 
ATOM   2816  C CA  . ARG A 1 385 ? 132.671 122.991 153.481 1.00 49.99  ? 385 ARG A CA  1 
ATOM   2817  C C   . ARG A 1 385 ? 132.506 124.120 152.471 1.00 49.99  ? 385 ARG A C   1 
ATOM   2818  O O   . ARG A 1 385 ? 131.375 124.500 152.150 1.00 49.99  ? 385 ARG A O   1 
ATOM   2819  C CB  . ARG A 1 385 ? 132.657 123.553 154.903 1.00 49.99  ? 385 ARG A CB  1 
ATOM   2820  C CG  . ARG A 1 385 ? 132.225 122.557 155.967 1.00 49.99  ? 385 ARG A CG  1 
ATOM   2821  C CD  . ARG A 1 385 ? 132.840 122.891 157.314 1.00 49.99  ? 385 ARG A CD  1 
ATOM   2822  N NE  . ARG A 1 385 ? 133.031 121.704 158.138 1.00 49.99  ? 385 ARG A NE  1 
ATOM   2823  C CZ  . ARG A 1 385 ? 133.871 121.630 159.160 1.00 49.99  ? 385 ARG A CZ  1 
ATOM   2824  N NH1 . ARG A 1 385 ? 134.619 122.661 159.516 1.00 49.99  ? 385 ARG A NH1 1 
ATOM   2825  N NH2 . ARG A 1 385 ? 133.964 120.493 159.842 1.00 49.99  ? 385 ARG A NH2 1 
ATOM   2826  N N   . VAL A 1 386 ? 133.605 124.665 151.963 1.00 47.18  ? 386 VAL A N   1 
ATOM   2827  C CA  . VAL A 1 386 ? 133.567 125.823 151.076 1.00 47.18  ? 386 VAL A CA  1 
ATOM   2828  C C   . VAL A 1 386 ? 133.835 125.435 149.628 1.00 47.18  ? 386 VAL A C   1 
ATOM   2829  O O   . VAL A 1 386 ? 133.106 125.844 148.725 1.00 47.18  ? 386 VAL A O   1 
ATOM   2830  C CB  . VAL A 1 386 ? 134.566 126.898 151.560 1.00 47.18  ? 386 VAL A CB  1 
ATOM   2831  C CG1 . VAL A 1 386 ? 134.668 128.026 150.546 1.00 47.18  ? 386 VAL A CG1 1 
ATOM   2832  C CG2 . VAL A 1 386 ? 134.148 127.434 152.917 1.00 47.18  ? 386 VAL A CG2 1 
ATOM   2833  N N   . ILE A 1 387 ? 134.872 124.645 149.385 1.00 50.25  ? 387 ILE A N   1 
ATOM   2834  C CA  . ILE A 1 387 ? 135.314 124.343 148.029 1.00 50.25  ? 387 ILE A CA  1 
ATOM   2835  C C   . ILE A 1 387 ? 134.830 122.954 147.634 1.00 50.25  ? 387 ILE A C   1 
ATOM   2836  O O   . ILE A 1 387 ? 134.708 122.046 148.464 1.00 50.25  ? 387 ILE A O   1 
ATOM   2837  C CB  . ILE A 1 387 ? 136.849 124.479 147.900 1.00 50.25  ? 387 ILE A CB  1 
ATOM   2838  C CG1 . ILE A 1 387 ? 137.234 124.857 146.470 1.00 50.25  ? 387 ILE A CG1 1 
ATOM   2839  C CG2 . ILE A 1 387 ? 137.564 123.211 148.349 1.00 50.25  ? 387 ILE A CG2 1 
ATOM   2840  C CD1 . ILE A 1 387 ? 138.465 125.730 146.382 1.00 50.25  ? 387 ILE A CD1 1 
ATOM   2841  N N   . GLU A 1 388 ? 134.524 122.801 146.349 1.00 55.17  ? 388 GLU A N   1 
ATOM   2842  C CA  . GLU A 1 388 ? 133.989 121.561 145.808 1.00 55.17  ? 388 GLU A CA  1 
ATOM   2843  C C   . GLU A 1 388 ? 135.102 120.532 145.621 1.00 55.17  ? 388 GLU A C   1 
ATOM   2844  O O   . GLU A 1 388 ? 136.289 120.863 145.568 1.00 55.17  ? 388 GLU A O   1 
ATOM   2845  C CB  . GLU A 1 388 ? 133.278 121.821 144.479 1.00 55.17  ? 388 GLU A CB  1 
ATOM   2846  C CG  . GLU A 1 388 ? 132.611 123.187 144.385 1.00 55.17  ? 388 GLU A CG  1 
ATOM   2847  C CD  . GLU A 1 388 ? 133.563 124.270 143.902 1.00 55.17  ? 388 GLU A CD  1 
ATOM   2848  O OE1 . GLU A 1 388 ? 134.610 123.924 143.317 1.00 55.17  ? 388 GLU A OE1 1 
ATOM   2849  O OE2 . GLU A 1 388 ? 133.270 125.465 144.119 1.00 55.17  ? 388 GLU A OE2 1 
ATOM   2850  N N   . LYS A 1 389 ? 134.698 119.264 145.519 1.00 59.23  ? 389 LYS A N   1 
ATOM   2851  C CA  . LYS A 1 389 ? 135.671 118.175 145.481 1.00 59.23  ? 389 LYS A CA  1 
ATOM   2852  C C   . LYS A 1 389 ? 136.506 118.217 144.205 1.00 59.23  ? 389 LYS A C   1 
ATOM   2853  O O   . LYS A 1 389 ? 137.724 118.423 144.253 1.00 59.23  ? 389 LYS A O   1 
ATOM   2854  C CB  . LYS A 1 389 ? 134.954 116.829 145.613 1.00 59.23  ? 389 LYS A CB  1 
ATOM   2855  C CG  . LYS A 1 389 ? 135.866 115.681 146.024 1.00 59.23  ? 389 LYS A CG  1 
ATOM   2856  C CD  . LYS A 1 389 ? 135.072 114.417 146.316 1.00 59.23  ? 389 LYS A CD  1 
ATOM   2857  C CE  . LYS A 1 389 ? 135.982 113.289 146.776 1.00 59.23  ? 389 LYS A CE  1 
ATOM   2858  N NZ  . LYS A 1 389 ? 135.215 112.069 147.151 1.00 59.23  ? 389 LYS A NZ  1 
ATOM   2859  N N   . THR A 1 390 ? 135.866 118.037 143.053 1.00 53.95  ? 390 THR A N   1 
ATOM   2860  C CA  . THR A 1 390 ? 136.565 118.038 141.774 1.00 53.95  ? 390 THR A CA  1 
ATOM   2861  C C   . THR A 1 390 ? 135.635 118.576 140.700 1.00 53.95  ? 390 THR A C   1 
ATOM   2862  O O   . THR A 1 390 ? 134.480 118.150 140.608 1.00 53.95  ? 390 THR A O   1 
ATOM   2863  C CB  . THR A 1 390 ? 137.042 116.631 141.382 1.00 53.95  ? 390 THR A CB  1 
ATOM   2864  O OG1 . THR A 1 390 ? 136.068 115.658 141.782 1.00 53.95  ? 390 THR A OG1 1 
ATOM   2865  C CG2 . THR A 1 390 ? 138.392 116.306 142.013 1.00 53.95  ? 390 THR A CG2 1 
ATOM   2866  N N   . ASN A 1 391 ? 136.142 119.501 139.893 1.00 46.27  ? 391 ASN A N   1 
ATOM   2867  C CA  . ASN A 1 391 ? 135.432 120.005 138.725 1.00 46.27  ? 391 ASN A CA  1 
ATOM   2868  C C   . ASN A 1 391 ? 135.990 119.311 137.490 1.00 46.27  ? 391 ASN A C   1 
ATOM   2869  O O   . ASN A 1 391 ? 137.191 119.400 137.214 1.00 46.27  ? 391 ASN A O   1 
ATOM   2870  C CB  . ASN A 1 391 ? 135.569 121.524 138.612 1.00 46.27  ? 391 ASN A CB  1 
ATOM   2871  C CG  . ASN A 1 391 ? 137.006 121.994 138.754 1.00 46.27  ? 391 ASN A CG  1 
ATOM   2872  O OD1 . ASN A 1 391 ? 137.630 121.816 139.800 1.00 46.27  ? 391 ASN A OD1 1 
ATOM   2873  N ND2 . ASN A 1 391 ? 137.538 122.599 137.699 1.00 46.27  ? 391 ASN A ND2 1 
ATOM   2874  N N   . GLU A 1 392 ? 135.124 118.615 136.759 1.00 42.00  ? 392 GLU A N   1 
ATOM   2875  C CA  . GLU A 1 392 ? 135.521 117.903 135.551 1.00 42.00  ? 392 GLU A CA  1 
ATOM   2876  C C   . GLU A 1 392 ? 135.266 118.781 134.332 1.00 42.00  ? 392 GLU A C   1 
ATOM   2877  O O   . GLU A 1 392 ? 134.126 119.179 134.076 1.00 42.00  ? 392 GLU A O   1 
ATOM   2878  C CB  . GLU A 1 392 ? 134.761 116.585 135.424 1.00 42.00  ? 392 GLU A CB  1 
ATOM   2879  C CG  . GLU A 1 392 ? 135.506 115.384 135.959 1.00 42.00  ? 392 GLU A CG  1 
ATOM   2880  C CD  . GLU A 1 392 ? 134.828 114.074 135.610 1.00 42.00  ? 392 GLU A CD  1 
ATOM   2881  O OE1 . GLU A 1 392 ? 133.657 113.888 136.000 1.00 42.00  ? 392 GLU A OE1 1 
ATOM   2882  O OE2 . GLU A 1 392 ? 135.467 113.228 134.950 1.00 42.00  ? 392 GLU A OE2 1 
ATOM   2883  N N   . LYS A 1 393 ? 136.326 119.075 133.584 1.00 36.40  ? 393 LYS A N   1 
ATOM   2884  C CA  . LYS A 1 393 ? 136.239 119.812 132.331 1.00 36.40  ? 393 LYS A CA  1 
ATOM   2885  C C   . LYS A 1 393 ? 136.931 119.000 131.249 1.00 36.40  ? 393 LYS A C   1 
ATOM   2886  O O   . LYS A 1 393 ? 137.984 118.405 131.494 1.00 36.40  ? 393 LYS A O   1 
ATOM   2887  C CB  . LYS A 1 393 ? 136.883 121.199 132.448 1.00 36.40  ? 393 LYS A CB  1 
ATOM   2888  C CG  . LYS A 1 393 ? 136.543 121.937 133.728 1.00 36.40  ? 393 LYS A CG  1 
ATOM   2889  C CD  . LYS A 1 393 ? 135.272 122.751 133.580 1.00 36.40  ? 393 LYS A CD  1 
ATOM   2890  C CE  . LYS A 1 393 ? 134.820 123.307 134.920 1.00 36.40  ? 393 LYS A CE  1 
ATOM   2891  N NZ  . LYS A 1 393 ? 133.367 123.626 134.933 1.00 36.40  ? 393 LYS A NZ  1 
ATOM   2892  N N   . PHE A 1 394 ? 136.339 118.958 130.056 1.00 34.88  ? 394 PHE A N   1 
ATOM   2893  C CA  . PHE A 1 394 ? 136.855 118.082 129.010 1.00 34.88  ? 394 PHE A CA  1 
ATOM   2894  C C   . PHE A 1 394 ? 137.389 118.837 127.800 1.00 34.88  ? 394 PHE A C   1 
ATOM   2895  O O   . PHE A 1 394 ? 138.581 118.727 127.499 1.00 34.88  ? 394 PHE A O   1 
ATOM   2896  C CB  . PHE A 1 394 ? 135.758 117.093 128.601 1.00 34.88  ? 394 PHE A CB  1 
ATOM   2897  C CG  . PHE A 1 394 ? 135.264 116.251 129.737 1.00 34.88  ? 394 PHE A CG  1 
ATOM   2898  C CD1 . PHE A 1 394 ? 136.048 115.233 130.251 1.00 34.88  ? 394 PHE A CD1 1 
ATOM   2899  C CD2 . PHE A 1 394 ? 134.026 116.490 130.308 1.00 34.88  ? 394 PHE A CD2 1 
ATOM   2900  C CE1 . PHE A 1 394 ? 135.602 114.460 131.305 1.00 34.88  ? 394 PHE A CE1 1 
ATOM   2901  C CE2 . PHE A 1 394 ? 133.573 115.720 131.360 1.00 34.88  ? 394 PHE A CE2 1 
ATOM   2902  C CZ  . PHE A 1 394 ? 134.362 114.703 131.858 1.00 34.88  ? 394 PHE A CZ  1 
ATOM   2903  N N   . HIS A 1 395 ? 136.570 119.628 127.118 1.00 31.89  ? 395 HIS A N   1 
ATOM   2904  C CA  . HIS A 1 395 ? 136.999 120.344 125.925 1.00 31.89  ? 395 HIS A CA  1 
ATOM   2905  C C   . HIS A 1 395 ? 136.914 121.839 126.186 1.00 31.89  ? 395 HIS A C   1 
ATOM   2906  O O   . HIS A 1 395 ? 135.868 122.343 126.603 1.00 31.89  ? 395 HIS A O   1 
ATOM   2907  C CB  . HIS A 1 395 ? 136.155 119.965 124.706 1.00 31.89  ? 395 HIS A CB  1 
ATOM   2908  C CG  . HIS A 1 395 ? 136.649 120.562 123.426 1.00 31.89  ? 395 HIS A CG  1 
ATOM   2909  N ND1 . HIS A 1 395 ? 137.935 120.373 122.965 1.00 31.89  ? 395 HIS A ND1 1 
ATOM   2910  C CD2 . HIS A 1 395 ? 136.038 121.356 122.515 1.00 31.89  ? 395 HIS A CD2 1 
ATOM   2911  C CE1 . HIS A 1 395 ? 138.091 121.019 121.824 1.00 31.89  ? 395 HIS A CE1 1 
ATOM   2912  N NE2 . HIS A 1 395 ? 136.955 121.623 121.528 1.00 31.89  ? 395 HIS A NE2 1 
ATOM   2913  N N   . GLN A 1 396 ? 138.016 122.539 125.939 1.00 32.00  ? 396 GLN A N   1 
ATOM   2914  C CA  . GLN A 1 396 ? 138.144 123.945 126.290 1.00 32.00  ? 396 GLN A CA  1 
ATOM   2915  C C   . GLN A 1 396 ? 138.791 124.671 125.116 1.00 32.00  ? 396 GLN A C   1 
ATOM   2916  O O   . GLN A 1 396 ? 138.908 124.130 124.013 1.00 32.00  ? 396 GLN A O   1 
ATOM   2917  C CB  . GLN A 1 396 ? 138.943 124.102 127.592 1.00 32.00  ? 396 GLN A CB  1 
ATOM   2918  C CG  . GLN A 1 396 ? 138.253 123.517 128.817 1.00 32.00  ? 396 GLN A CG  1 
ATOM   2919  C CD  . GLN A 1 396 ? 139.209 123.253 129.963 1.00 32.00  ? 396 GLN A CD  1 
ATOM   2920  O OE1 . GLN A 1 396 ? 139.573 124.163 130.706 1.00 32.00  ? 396 GLN A OE1 1 
ATOM   2921  N NE2 . GLN A 1 396 ? 139.623 122.002 130.111 1.00 32.00  ? 396 GLN A NE2 1 
ATOM   2922  N N   . ILE A 1 397 ? 139.207 125.905 125.355 1.00 29.24  ? 397 ILE A N   1 
ATOM   2923  C CA  . ILE A 1 397 ? 139.850 126.717 124.335 1.00 29.24  ? 397 ILE A CA  1 
ATOM   2924  C C   . ILE A 1 397 ? 141.341 126.403 124.301 1.00 29.24  ? 397 ILE A C   1 
ATOM   2925  O O   . ILE A 1 397 ? 141.899 125.800 125.220 1.00 29.24  ? 397 ILE A O   1 
ATOM   2926  C CB  . ILE A 1 397 ? 139.606 128.219 124.584 1.00 29.24  ? 397 ILE A CB  1 
ATOM   2927  C CG1 . ILE A 1 397 ? 140.191 128.634 125.936 1.00 29.24  ? 397 ILE A CG1 1 
ATOM   2928  C CG2 . ILE A 1 397 ? 138.123 128.533 124.519 1.00 29.24  ? 397 ILE A CG2 1 
ATOM   2929  C CD1 . ILE A 1 397 ? 140.346 130.124 126.106 1.00 29.24  ? 397 ILE A CD1 1 
ATOM   2930  N N   . GLU A 1 398 ? 141.993 126.813 123.217 1.00 31.09  ? 398 GLU A N   1 
ATOM   2931  C CA  . GLU A 1 398 ? 143.443 126.713 123.134 1.00 31.09  ? 398 GLU A CA  1 
ATOM   2932  C C   . GLU A 1 398 ? 144.090 127.790 123.996 1.00 31.09  ? 398 GLU A C   1 
ATOM   2933  O O   . GLU A 1 398 ? 143.584 128.910 124.101 1.00 31.09  ? 398 GLU A O   1 
ATOM   2934  C CB  . GLU A 1 398 ? 143.906 126.847 121.684 1.00 31.09  ? 398 GLU A CB  1 
ATOM   2935  C CG  . GLU A 1 398 ? 143.418 125.737 120.772 1.00 31.09  ? 398 GLU A CG  1 
ATOM   2936  C CD  . GLU A 1 398 ? 143.890 124.368 121.214 1.00 31.09  ? 398 GLU A CD  1 
ATOM   2937  O OE1 . GLU A 1 398 ? 145.108 124.194 121.419 1.00 31.09  ? 398 GLU A OE1 1 
ATOM   2938  O OE2 . GLU A 1 398 ? 143.043 123.463 121.363 1.00 31.09  ? 398 GLU A OE2 1 
ATOM   2939  N N   . LYS A 1 399 ? 145.218 127.448 124.614 1.00 29.79  ? 399 LYS A N   1 
ATOM   2940  C CA  . LYS A 1 399 ? 145.890 128.350 125.534 1.00 29.79  ? 399 LYS A CA  1 
ATOM   2941  C C   . LYS A 1 399 ? 147.345 128.615 125.171 1.00 29.79  ? 399 LYS A C   1 
ATOM   2942  O O   . LYS A 1 399 ? 147.996 129.418 125.846 1.00 29.79  ? 399 LYS A O   1 
ATOM   2943  C CB  . LYS A 1 399 ? 145.794 127.804 126.965 1.00 29.79  ? 399 LYS A CB  1 
ATOM   2944  C CG  . LYS A 1 399 ? 144.369 127.790 127.500 1.00 29.79  ? 399 LYS A CG  1 
ATOM   2945  C CD  . LYS A 1 399 ? 144.235 127.029 128.805 1.00 29.79  ? 399 LYS A CD  1 
ATOM   2946  C CE  . LYS A 1 399 ? 142.771 126.797 129.142 1.00 29.79  ? 399 LYS A CE  1 
ATOM   2947  N NZ  . LYS A 1 399 ? 142.581 126.162 130.470 1.00 29.79  ? 399 LYS A NZ  1 
ATOM   2948  N N   . GLU A 1 400 ? 147.871 127.974 124.130 1.00 33.03  ? 400 GLU A N   1 
ATOM   2949  C CA  . GLU A 1 400 ? 149.206 128.251 123.622 1.00 33.03  ? 400 GLU A CA  1 
ATOM   2950  C C   . GLU A 1 400 ? 149.137 128.342 122.106 1.00 33.03  ? 400 GLU A C   1 
ATOM   2951  O O   . GLU A 1 400 ? 148.394 127.593 121.467 1.00 33.03  ? 400 GLU A O   1 
ATOM   2952  C CB  . GLU A 1 400 ? 150.211 127.171 124.047 1.00 33.03  ? 400 GLU A CB  1 
ATOM   2953  C CG  . GLU A 1 400 ? 150.690 127.297 125.482 1.00 33.03  ? 400 GLU A CG  1 
ATOM   2954  C CD  . GLU A 1 400 ? 151.675 126.209 125.870 1.00 33.03  ? 400 GLU A CD  1 
ATOM   2955  O OE1 . GLU A 1 400 ? 152.490 125.805 125.015 1.00 33.03  ? 400 GLU A OE1 1 
ATOM   2956  O OE2 . GLU A 1 400 ? 151.636 125.757 127.032 1.00 33.03  ? 400 GLU A OE2 1 
ATOM   2957  N N   . PHE A 1 401 ? 149.914 129.258 121.533 1.00 32.62  ? 401 PHE A N   1 
ATOM   2958  C CA  . PHE A 1 401 ? 149.850 129.551 120.109 1.00 32.62  ? 401 PHE A CA  1 
ATOM   2959  C C   . PHE A 1 401 ? 151.250 129.604 119.517 1.00 32.62  ? 401 PHE A C   1 
ATOM   2960  O O   . PHE A 1 401 ? 152.204 130.027 120.173 1.00 32.62  ? 401 PHE A O   1 
ATOM   2961  C CB  . PHE A 1 401 ? 149.123 130.878 119.850 1.00 32.62  ? 401 PHE A CB  1 
ATOM   2962  C CG  . PHE A 1 401 ? 147.799 130.984 120.545 1.00 32.62  ? 401 PHE A CG  1 
ATOM   2963  C CD1 . PHE A 1 401 ? 146.640 130.546 119.927 1.00 32.62  ? 401 PHE A CD1 1 
ATOM   2964  C CD2 . PHE A 1 401 ? 147.713 131.512 121.823 1.00 32.62  ? 401 PHE A CD2 1 
ATOM   2965  C CE1 . PHE A 1 401 ? 145.420 130.637 120.569 1.00 32.62  ? 401 PHE A CE1 1 
ATOM   2966  C CE2 . PHE A 1 401 ? 146.498 131.603 122.468 1.00 32.62  ? 401 PHE A CE2 1 
ATOM   2967  C CZ  . PHE A 1 401 ? 145.350 131.166 121.841 1.00 32.62  ? 401 PHE A CZ  1 
ATOM   2968  N N   . SER A 1 402 ? 151.360 129.182 118.258 1.00 37.64  ? 402 SER A N   1 
ATOM   2969  C CA  . SER A 1 402 ? 152.640 129.162 117.565 1.00 37.64  ? 402 SER A CA  1 
ATOM   2970  C C   . SER A 1 402 ? 152.796 130.278 116.540 1.00 37.64  ? 402 SER A C   1 
ATOM   2971  O O   . SER A 1 402 ? 153.926 130.567 116.135 1.00 37.64  ? 402 SER A O   1 
ATOM   2972  C CB  . SER A 1 402 ? 152.849 127.807 116.875 1.00 37.64  ? 402 SER A CB  1 
ATOM   2973  O OG  . SER A 1 402 ? 151.928 127.621 115.817 1.00 37.64  ? 402 SER A OG  1 
ATOM   2974  N N   . GLU A 1 403 ? 151.704 130.912 116.118 1.00 38.81  ? 403 GLU A N   1 
ATOM   2975  C CA  . GLU A 1 403 ? 151.754 132.016 115.172 1.00 38.81  ? 403 GLU A CA  1 
ATOM   2976  C C   . GLU A 1 403 ? 150.999 133.209 115.741 1.00 38.81  ? 403 GLU A C   1 
ATOM   2977  O O   . GLU A 1 403 ? 150.162 133.071 116.636 1.00 38.81  ? 403 GLU A O   1 
ATOM   2978  C CB  . GLU A 1 403 ? 151.159 131.633 113.808 1.00 38.81  ? 403 GLU A CB  1 
ATOM   2979  C CG  . GLU A 1 403 ? 151.292 130.163 113.437 1.00 38.81  ? 403 GLU A CG  1 
ATOM   2980  C CD  . GLU A 1 403 ? 152.716 129.758 113.098 1.00 38.81  ? 403 GLU A CD  1 
ATOM   2981  O OE1 . GLU A 1 403 ? 153.548 130.649 112.827 1.00 38.81  ? 403 GLU A OE1 1 
ATOM   2982  O OE2 . GLU A 1 403 ? 153.002 128.542 113.104 1.00 38.81  ? 403 GLU A OE2 1 
ATOM   2983  N N   . VAL A 1 404 ? 151.309 134.390 115.216 1.00 36.69  ? 404 VAL A N   1 
ATOM   2984  C CA  . VAL A 1 404 ? 150.631 135.620 115.609 1.00 36.69  ? 404 VAL A CA  1 
ATOM   2985  C C   . VAL A 1 404 ? 149.419 135.819 114.710 1.00 36.69  ? 404 VAL A C   1 
ATOM   2986  O O   . VAL A 1 404 ? 149.513 135.693 113.484 1.00 36.69  ? 404 VAL A O   1 
ATOM   2987  C CB  . VAL A 1 404 ? 151.582 136.827 115.539 1.00 36.69  ? 404 VAL A CB  1 
ATOM   2988  C CG1 . VAL A 1 404 ? 152.573 136.790 116.687 1.00 36.69  ? 404 VAL A CG1 1 
ATOM   2989  C CG2 . VAL A 1 404 ? 152.315 136.850 114.218 1.00 36.69  ? 404 VAL A CG2 1 
ATOM   2990  N N   . GLU A 1 405 ? 148.279 136.108 115.316 1.00 34.70  ? 405 GLU A N   1 
ATOM   2991  C CA  . GLU A 1 405 ? 147.033 136.228 114.566 1.00 34.70  ? 405 GLU A CA  1 
ATOM   2992  C C   . GLU A 1 405 ? 146.325 137.558 114.774 1.00 34.70  ? 405 GLU A C   1 
ATOM   2993  O O   . GLU A 1 405 ? 145.785 138.112 113.816 1.00 34.70  ? 405 GLU A O   1 
ATOM   2994  C CB  . GLU A 1 405 ? 146.089 135.081 114.944 1.00 34.70  ? 405 GLU A CB  1 
ATOM   2995  C CG  . GLU A 1 405 ? 146.659 133.700 114.702 1.00 34.70  ? 405 GLU A CG  1 
ATOM   2996  C CD  . GLU A 1 405 ? 145.710 132.600 115.129 1.00 34.70  ? 405 GLU A CD  1 
ATOM   2997  O OE1 . GLU A 1 405 ? 144.653 132.447 114.485 1.00 34.70  ? 405 GLU A OE1 1 
ATOM   2998  O OE2 . GLU A 1 405 ? 146.019 131.891 116.109 1.00 34.70  ? 405 GLU A OE2 1 
ATOM   2999  N N   . GLY A 1 406 ? 146.306 138.081 115.996 1.00 31.45  ? 406 GLY A N   1 
ATOM   3000  C CA  . GLY A 1 406 ? 145.662 139.354 116.250 1.00 31.45  ? 406 GLY A CA  1 
ATOM   3001  C C   . GLY A 1 406 ? 144.501 139.317 117.225 1.00 31.45  ? 406 GLY A C   1 
ATOM   3002  O O   . GLY A 1 406 ? 144.662 138.922 118.381 1.00 31.45  ? 406 GLY A O   1 
ATOM   3003  N N   . ARG A 1 407 ? 143.318 139.711 116.747 1.00 30.95  ? 407 ARG A N   1 
ATOM   3004  C CA  . ARG A 1 407 ? 142.206 140.051 117.634 1.00 30.95  ? 407 ARG A CA  1 
ATOM   3005  C C   . ARG A 1 407 ? 141.745 138.854 118.466 1.00 30.95  ? 407 ARG A C   1 
ATOM   3006  O O   . ARG A 1 407 ? 141.657 138.936 119.699 1.00 30.95  ? 407 ARG A O   1 
ATOM   3007  C CB  . ARG A 1 407 ? 141.053 140.608 116.795 1.00 30.95  ? 407 ARG A CB  1 
ATOM   3008  C CG  . ARG A 1 407 ? 140.210 141.668 117.472 1.00 30.95  ? 407 ARG A CG  1 
ATOM   3009  C CD  . ARG A 1 407 ? 139.094 142.140 116.549 1.00 30.95  ? 407 ARG A CD  1 
ATOM   3010  N NE  . ARG A 1 407 ? 138.078 142.906 117.260 1.00 30.95  ? 407 ARG A NE  1 
ATOM   3011  C CZ  . ARG A 1 407 ? 137.113 143.601 116.675 1.00 30.95  ? 407 ARG A CZ  1 
ATOM   3012  N NH1 . ARG A 1 407 ? 136.998 143.650 115.358 1.00 30.95  ? 407 ARG A NH1 1 
ATOM   3013  N NH2 . ARG A 1 407 ? 136.242 144.264 117.429 1.00 30.95  ? 407 ARG A NH2 1 
ATOM   3014  N N   . ILE A 1 408 ? 141.450 137.731 117.807 1.00 29.94  ? 408 ILE A N   1 
ATOM   3015  C CA  . ILE A 1 408 ? 140.876 136.581 118.504 1.00 29.94  ? 408 ILE A CA  1 
ATOM   3016  C C   . ILE A 1 408 ? 141.877 135.987 119.490 1.00 29.94  ? 408 ILE A C   1 
ATOM   3017  O O   . ILE A 1 408 ? 141.512 135.593 120.607 1.00 29.94  ? 408 ILE A O   1 
ATOM   3018  C CB  . ILE A 1 408 ? 140.388 135.531 117.488 1.00 29.94  ? 408 ILE A CB  1 
ATOM   3019  C CG1 . ILE A 1 408 ? 139.567 136.190 116.378 1.00 29.94  ? 408 ILE A CG1 1 
ATOM   3020  C CG2 . ILE A 1 408 ? 139.561 134.459 118.179 1.00 29.94  ? 408 ILE A CG2 1 
ATOM   3021  C CD1 . ILE A 1 408 ? 138.292 136.851 116.859 1.00 29.94  ? 408 ILE A CD1 1 
ATOM   3022  N N   . GLN A 1 409 ? 143.148 135.897 119.091 1.00 30.71  ? 409 GLN A N   1 
ATOM   3023  C CA  . GLN A 1 409 ? 144.172 135.375 119.990 1.00 30.71  ? 409 GLN A CA  1 
ATOM   3024  C C   . GLN A 1 409 ? 144.350 136.282 121.204 1.00 30.71  ? 409 GLN A C   1 
ATOM   3025  O O   . GLN A 1 409 ? 144.505 135.799 122.335 1.00 30.71  ? 409 GLN A O   1 
ATOM   3026  C CB  . GLN A 1 409 ? 145.491 135.203 119.235 1.00 30.71  ? 409 GLN A CB  1 
ATOM   3027  C CG  . GLN A 1 409 ? 146.541 134.409 119.989 1.00 30.71  ? 409 GLN A CG  1 
ATOM   3028  C CD  . GLN A 1 409 ? 147.854 134.300 119.236 1.00 30.71  ? 409 GLN A CD  1 
ATOM   3029  O OE1 . GLN A 1 409 ? 148.886 134.777 119.701 1.00 30.71  ? 409 GLN A OE1 1 
ATOM   3030  N NE2 . GLN A 1 409 ? 147.821 133.663 118.074 1.00 30.71  ? 409 GLN A NE2 1 
ATOM   3031  N N   . ASP A 1 410 ? 144.322 137.601 120.987 1.00 29.98  ? 410 ASP A N   1 
ATOM   3032  C CA  . ASP A 1 410 ? 144.374 138.542 122.102 1.00 29.98  ? 410 ASP A CA  1 
ATOM   3033  C C   . ASP A 1 410 ? 143.222 138.306 123.069 1.00 29.98  ? 410 ASP A C   1 
ATOM   3034  O O   . ASP A 1 410 ? 143.419 138.296 124.291 1.00 29.98  ? 410 ASP A O   1 
ATOM   3035  C CB  . ASP A 1 410 ? 144.340 139.981 121.585 1.00 29.98  ? 410 ASP A CB  1 
ATOM   3036  C CG  . ASP A 1 410 ? 145.602 140.373 120.844 1.00 29.98  ? 410 ASP A CG  1 
ATOM   3037  O OD1 . ASP A 1 410 ? 146.660 139.759 121.085 1.00 29.98  ? 410 ASP A OD1 1 
ATOM   3038  O OD2 . ASP A 1 410 ? 145.533 141.305 120.016 1.00 29.98  ? 410 ASP A OD2 1 
ATOM   3039  N N   . LEU A 1 411 ? 142.014 138.096 122.539 1.00 27.58  ? 411 LEU A N   1 
ATOM   3040  C CA  . LEU A 1 411 ? 140.861 137.861 123.405 1.00 27.58  ? 411 LEU A CA  1 
ATOM   3041  C C   . LEU A 1 411 ? 141.012 136.571 124.210 1.00 27.58  ? 411 LEU A C   1 
ATOM   3042  O O   . LEU A 1 411 ? 140.718 136.543 125.413 1.00 27.58  ? 411 LEU A O   1 
ATOM   3043  C CB  . LEU A 1 411 ? 139.582 137.831 122.569 1.00 27.58  ? 411 LEU A CB  1 
ATOM   3044  C CG  . LEU A 1 411 ? 138.256 137.794 123.330 1.00 27.58  ? 411 LEU A CG  1 
ATOM   3045  C CD1 . LEU A 1 411 ? 138.225 138.846 124.426 1.00 27.58  ? 411 LEU A CD1 1 
ATOM   3046  C CD2 . LEU A 1 411 ? 137.091 137.979 122.375 1.00 27.58  ? 411 LEU A CD2 1 
ATOM   3047  N N   . GLU A 1 412 ? 141.463 135.493 123.563 1.00 28.82  ? 412 GLU A N   1 
ATOM   3048  C CA  . GLU A 1 412 ? 141.634 134.224 124.270 1.00 28.82  ? 412 GLU A CA  1 
ATOM   3049  C C   . GLU A 1 412 ? 142.661 134.344 125.394 1.00 28.82  ? 412 GLU A C   1 
ATOM   3050  O O   . GLU A 1 412 ? 142.425 133.880 126.525 1.00 28.82  ? 412 GLU A O   1 
ATOM   3051  C CB  . GLU A 1 412 ? 142.039 133.129 123.283 1.00 28.82  ? 412 GLU A CB  1 
ATOM   3052  C CG  . GLU A 1 412 ? 140.904 132.639 122.403 1.00 28.82  ? 412 GLU A CG  1 
ATOM   3053  C CD  . GLU A 1 412 ? 141.379 132.136 121.054 1.00 28.82  ? 412 GLU A CD  1 
ATOM   3054  O OE1 . GLU A 1 412 ? 142.515 132.467 120.658 1.00 28.82  ? 412 GLU A OE1 1 
ATOM   3055  O OE2 . GLU A 1 412 ? 140.613 131.410 120.387 1.00 28.82  ? 412 GLU A OE2 1 
ATOM   3056  N N   . LYS A 1 413 ? 143.798 134.987 125.107 1.00 28.33  ? 413 LYS A N   1 
ATOM   3057  C CA  . LYS A 1 413 ? 144.816 135.182 126.134 1.00 28.33  ? 413 LYS A CA  1 
ATOM   3058  C C   . LYS A 1 413 ? 144.281 136.018 127.291 1.00 28.33  ? 413 LYS A C   1 
ATOM   3059  O O   . LYS A 1 413 ? 144.536 135.707 128.462 1.00 28.33  ? 413 LYS A O   1 
ATOM   3060  C CB  . LYS A 1 413 ? 146.057 135.837 125.527 1.00 28.33  ? 413 LYS A CB  1 
ATOM   3061  C CG  . LYS A 1 413 ? 146.938 134.881 124.746 1.00 28.33  ? 413 LYS A CG  1 
ATOM   3062  C CD  . LYS A 1 413 ? 147.924 135.629 123.866 1.00 28.33  ? 413 LYS A CD  1 
ATOM   3063  C CE  . LYS A 1 413 ? 149.005 134.705 123.342 1.00 28.33  ? 413 LYS A CE  1 
ATOM   3064  N NZ  . LYS A 1 413 ? 150.185 135.453 122.832 1.00 28.33  ? 413 LYS A NZ  1 
ATOM   3065  N N   . TYR A 1 414 ? 143.530 137.080 126.981 1.00 25.76  ? 414 TYR A N   1 
ATOM   3066  C CA  . TYR A 1 414 ? 142.977 137.934 128.026 1.00 25.76  ? 414 TYR A CA  1 
ATOM   3067  C C   . TYR A 1 414 ? 142.014 137.164 128.925 1.00 25.76  ? 414 TYR A C   1 
ATOM   3068  O O   . TYR A 1 414 ? 142.040 137.318 130.154 1.00 25.76  ? 414 TYR A O   1 
ATOM   3069  C CB  . TYR A 1 414 ? 142.284 139.136 127.385 1.00 25.76  ? 414 TYR A CB  1 
ATOM   3070  C CG  . TYR A 1 414 ? 141.874 140.226 128.344 1.00 25.76  ? 414 TYR A CG  1 
ATOM   3071  C CD1 . TYR A 1 414 ? 142.809 141.106 128.868 1.00 25.76  ? 414 TYR A CD1 1 
ATOM   3072  C CD2 . TYR A 1 414 ? 140.547 140.387 128.710 1.00 25.76  ? 414 TYR A CD2 1 
ATOM   3073  C CE1 . TYR A 1 414 ? 142.436 142.107 129.738 1.00 25.76  ? 414 TYR A CE1 1 
ATOM   3074  C CE2 . TYR A 1 414 ? 140.164 141.385 129.578 1.00 25.76  ? 414 TYR A CE2 1 
ATOM   3075  C CZ  . TYR A 1 414 ? 141.111 142.242 130.088 1.00 25.76  ? 414 TYR A CZ  1 
ATOM   3076  O OH  . TYR A 1 414 ? 140.731 143.238 130.953 1.00 25.76  ? 414 TYR A OH  1 
ATOM   3077  N N   . VAL A 1 415 ? 141.164 136.324 128.330 1.00 25.54  ? 415 VAL A N   1 
ATOM   3078  C CA  . VAL A 1 415 ? 140.205 135.547 129.115 1.00 25.54  ? 415 VAL A CA  1 
ATOM   3079  C C   . VAL A 1 415 ? 140.936 134.610 130.073 1.00 25.54  ? 415 VAL A C   1 
ATOM   3080  O O   . VAL A 1 415 ? 140.617 134.536 131.273 1.00 25.54  ? 415 VAL A O   1 
ATOM   3081  C CB  . VAL A 1 415 ? 139.256 134.775 128.179 1.00 25.54  ? 415 VAL A CB  1 
ATOM   3082  C CG1 . VAL A 1 415 ? 138.519 133.680 128.932 1.00 25.54  ? 415 VAL A CG1 1 
ATOM   3083  C CG2 . VAL A 1 415 ? 138.276 135.727 127.504 1.00 25.54  ? 415 VAL A CG2 1 
ATOM   3084  N N   . GLU A 1 416 ? 141.943 133.892 129.560 1.00 26.87  ? 416 GLU A N   1 
ATOM   3085  C CA  . GLU A 1 416 ? 142.669 132.957 130.418 1.00 26.87  ? 416 GLU A CA  1 
ATOM   3086  C C   . GLU A 1 416 ? 143.396 133.685 131.549 1.00 26.87  ? 416 GLU A C   1 
ATOM   3087  O O   . GLU A 1 416 ? 143.389 133.227 132.702 1.00 26.87  ? 416 GLU A O   1 
ATOM   3088  C CB  . GLU A 1 416 ? 143.647 132.129 129.584 1.00 26.87  ? 416 GLU A CB  1 
ATOM   3089  C CG  . GLU A 1 416 ? 144.296 130.964 130.325 1.00 26.87  ? 416 GLU A CG  1 
ATOM   3090  C CD  . GLU A 1 416 ? 143.293 130.050 131.019 1.00 26.87  ? 416 GLU A CD  1 
ATOM   3091  O OE1 . GLU A 1 416 ? 142.149 129.921 130.537 1.00 26.87  ? 416 GLU A OE1 1 
ATOM   3092  O OE2 . GLU A 1 416 ? 143.654 129.447 132.049 1.00 26.87  ? 416 GLU A OE2 1 
ATOM   3093  N N   . ASP A 1 417 ? 144.012 134.831 131.241 1.00 27.09  ? 417 ASP A N   1 
ATOM   3094  C CA  . ASP A 1 417 ? 144.725 135.593 132.263 1.00 27.09  ? 417 ASP A CA  1 
ATOM   3095  C C   . ASP A 1 417 ? 143.784 136.076 133.365 1.00 27.09  ? 417 ASP A C   1 
ATOM   3096  O O   . ASP A 1 417 ? 144.117 135.999 134.559 1.00 27.09  ? 417 ASP A O   1 
ATOM   3097  C CB  . ASP A 1 417 ? 145.442 136.774 131.614 1.00 27.09  ? 417 ASP A CB  1 
ATOM   3098  C CG  . ASP A 1 417 ? 146.442 137.426 132.537 1.00 27.09  ? 417 ASP A CG  1 
ATOM   3099  O OD1 . ASP A 1 417 ? 147.456 136.778 132.866 1.00 27.09  ? 417 ASP A OD1 1 
ATOM   3100  O OD2 . ASP A 1 417 ? 146.215 138.587 132.933 1.00 27.09  ? 417 ASP A OD2 1 
ATOM   3101  N N   . THR A 1 418 ? 142.608 136.583 132.981 1.00 24.70  ? 418 THR A N   1 
ATOM   3102  C CA  . THR A 1 418 ? 141.639 137.040 133.973 1.00 24.70  ? 418 THR A CA  1 
ATOM   3103  C C   . THR A 1 418 ? 141.213 135.901 134.894 1.00 24.70  ? 418 THR A C   1 
ATOM   3104  O O   . THR A 1 418 ? 141.163 136.064 136.126 1.00 24.70  ? 418 THR A O   1 
ATOM   3105  C CB  . THR A 1 418 ? 140.424 137.645 133.266 1.00 24.70  ? 418 THR A CB  1 
ATOM   3106  O OG1 . THR A 1 418 ? 140.847 138.725 132.427 1.00 24.70  ? 418 THR A OG1 1 
ATOM   3107  C CG2 . THR A 1 418 ? 139.404 138.156 134.272 1.00 24.70  ? 418 THR A CG2 1 
ATOM   3108  N N   . LYS A 1 419 ? 140.923 134.733 134.313 1.00 23.97  ? 419 LYS A N   1 
ATOM   3109  C CA  . LYS A 1 419 ? 140.509 133.591 135.124 1.00 23.97  ? 419 LYS A CA  1 
ATOM   3110  C C   . LYS A 1 419 ? 141.593 133.204 136.127 1.00 23.97  ? 419 LYS A C   1 
ATOM   3111  O O   . LYS A 1 419 ? 141.310 132.973 137.315 1.00 23.97  ? 419 LYS A O   1 
ATOM   3112  C CB  . LYS A 1 419 ? 140.166 132.414 134.211 1.00 23.97  ? 419 LYS A CB  1 
ATOM   3113  C CG  . LYS A 1 419 ? 139.822 131.124 134.923 1.00 23.97  ? 419 LYS A CG  1 
ATOM   3114  C CD  . LYS A 1 419 ? 139.508 130.036 133.914 1.00 23.97  ? 419 LYS A CD  1 
ATOM   3115  C CE  . LYS A 1 419 ? 138.734 128.893 134.536 1.00 23.97  ? 419 LYS A CE  1 
ATOM   3116  N NZ  . LYS A 1 419 ? 139.400 127.588 134.301 1.00 23.97  ? 419 LYS A NZ  1 
ATOM   3117  N N   . VAL A 1 420 ? 142.846 133.146 135.665 1.00 23.69  ? 420 VAL A N   1 
ATOM   3118  C CA  . VAL A 1 420 ? 143.941 132.731 136.539 1.00 23.69  ? 420 VAL A CA  1 
ATOM   3119  C C   . VAL A 1 420 ? 144.111 133.708 137.697 1.00 23.69  ? 420 VAL A C   1 
ATOM   3120  O O   . VAL A 1 420 ? 144.269 133.298 138.857 1.00 23.69  ? 420 VAL A O   1 
ATOM   3121  C CB  . VAL A 1 420 ? 145.242 132.576 135.729 1.00 23.69  ? 420 VAL A CB  1 
ATOM   3122  C CG1 . VAL A 1 420 ? 146.440 132.504 136.652 1.00 23.69  ? 420 VAL A CG1 1 
ATOM   3123  C CG2 . VAL A 1 420 ? 145.176 131.336 134.857 1.00 23.69  ? 420 VAL A CG2 1 
ATOM   3124  N N   . ASP A 1 421 ? 144.078 135.013 137.407 1.00 25.60  ? 421 ASP A N   1 
ATOM   3125  C CA  . ASP A 1 421 ? 144.269 135.996 138.471 1.00 25.60  ? 421 ASP A CA  1 
ATOM   3126  C C   . ASP A 1 421 ? 143.167 135.901 139.525 1.00 25.60  ? 421 ASP A C   1 
ATOM   3127  O O   . ASP A 1 421 ? 143.447 135.919 140.738 1.00 25.60  ? 421 ASP A O   1 
ATOM   3128  C CB  . ASP A 1 421 ? 144.331 137.403 137.880 1.00 25.60  ? 421 ASP A CB  1 
ATOM   3129  C CG  . ASP A 1 421 ? 145.661 137.697 137.214 1.00 25.60  ? 421 ASP A CG  1 
ATOM   3130  O OD1 . ASP A 1 421 ? 146.638 136.970 137.486 1.00 25.60  ? 421 ASP A OD1 1 
ATOM   3131  O OD2 . ASP A 1 421 ? 145.733 138.656 136.419 1.00 25.60  ? 421 ASP A OD2 1 
ATOM   3132  N N   . LEU A 1 422 ? 141.910 135.771 139.085 1.00 22.75  ? 422 LEU A N   1 
ATOM   3133  C CA  . LEU A 1 422 ? 140.816 135.700 140.050 1.00 22.75  ? 422 LEU A CA  1 
ATOM   3134  C C   . LEU A 1 422 ? 140.919 134.454 140.930 1.00 22.75  ? 422 LEU A C   1 
ATOM   3135  O O   . LEU A 1 422 ? 140.732 134.531 142.155 1.00 22.75  ? 422 LEU A O   1 
ATOM   3136  C CB  . LEU A 1 422 ? 139.469 135.754 139.328 1.00 22.75  ? 422 LEU A CB  1 
ATOM   3137  C CG  . LEU A 1 422 ? 139.055 137.159 138.873 1.00 22.75  ? 422 LEU A CG  1 
ATOM   3138  C CD1 . LEU A 1 422 ? 138.024 137.109 137.756 1.00 22.75  ? 422 LEU A CD1 1 
ATOM   3139  C CD2 . LEU A 1 422 ? 138.549 137.991 140.043 1.00 22.75  ? 422 LEU A CD2 1 
ATOM   3140  N N   . TRP A 1 423 ? 141.239 133.297 140.337 1.00 22.79  ? 423 TRP A N   1 
ATOM   3141  C CA  . TRP A 1 423 ? 141.321 132.090 141.160 1.00 22.79  ? 423 TRP A CA  1 
ATOM   3142  C C   . TRP A 1 423 ? 142.510 132.124 142.122 1.00 22.79  ? 423 TRP A C   1 
ATOM   3143  O O   . TRP A 1 423 ? 142.402 131.623 143.252 1.00 22.79  ? 423 TRP A O   1 
ATOM   3144  C CB  . TRP A 1 423 ? 141.360 130.840 140.280 1.00 22.79  ? 423 TRP A CB  1 
ATOM   3145  C CG  . TRP A 1 423 ? 139.986 130.351 139.928 1.00 22.79  ? 423 TRP A CG  1 
ATOM   3146  C CD1 . TRP A 1 423 ? 139.427 130.303 138.686 1.00 22.79  ? 423 TRP A CD1 1 
ATOM   3147  C CD2 . TRP A 1 423 ? 138.985 129.875 140.836 1.00 22.79  ? 423 TRP A CD2 1 
ATOM   3148  N NE1 . TRP A 1 423 ? 138.148 129.816 138.761 1.00 22.79  ? 423 TRP A NE1 1 
ATOM   3149  C CE2 . TRP A 1 423 ? 137.852 129.544 140.070 1.00 22.79  ? 423 TRP A CE2 1 
ATOM   3150  C CE3 . TRP A 1 423 ? 138.940 129.690 142.222 1.00 22.79  ? 423 TRP A CE3 1 
ATOM   3151  C CZ2 . TRP A 1 423 ? 136.685 129.041 140.642 1.00 22.79  ? 423 TRP A CZ2 1 
ATOM   3152  C CZ3 . TRP A 1 423 ? 137.782 129.191 142.788 1.00 22.79  ? 423 TRP A CZ3 1 
ATOM   3153  C CH2 . TRP A 1 423 ? 136.671 128.872 142.000 1.00 22.79  ? 423 TRP A CH2 1 
ATOM   3154  N N   . SER A 1 424 ? 143.639 132.714 141.714 1.00 24.58  ? 424 SER A N   1 
ATOM   3155  C CA  . SER A 1 424 ? 144.765 132.844 142.639 1.00 24.58  ? 424 SER A CA  1 
ATOM   3156  C C   . SER A 1 424 ? 144.398 133.709 143.842 1.00 24.58  ? 424 SER A C   1 
ATOM   3157  O O   . SER A 1 424 ? 144.727 133.368 144.992 1.00 24.58  ? 424 SER A O   1 
ATOM   3158  C CB  . SER A 1 424 ? 145.979 133.424 141.914 1.00 24.58  ? 424 SER A CB  1 
ATOM   3159  O OG  . SER A 1 424 ? 146.314 132.645 140.784 1.00 24.58  ? 424 SER A OG  1 
ATOM   3160  N N   . TYR A 1 425 ? 143.706 134.830 143.599 1.00 25.18  ? 425 TYR A N   1 
ATOM   3161  C CA  . TYR A 1 425 ? 143.265 135.659 144.718 1.00 25.18  ? 425 TYR A CA  1 
ATOM   3162  C C   . TYR A 1 425 ? 142.335 134.883 145.647 1.00 25.18  ? 425 TYR A C   1 
ATOM   3163  O O   . TYR A 1 425 ? 142.458 134.969 146.881 1.00 25.18  ? 425 TYR A O   1 
ATOM   3164  C CB  . TYR A 1 425 ? 142.578 136.925 144.203 1.00 25.18  ? 425 TYR A CB  1 
ATOM   3165  C CG  . TYR A 1 425 ? 141.892 137.730 145.287 1.00 25.18  ? 425 TYR A CG  1 
ATOM   3166  C CD1 . TYR A 1 425 ? 142.594 138.667 146.030 1.00 25.18  ? 425 TYR A CD1 1 
ATOM   3167  C CD2 . TYR A 1 425 ? 140.543 137.553 145.563 1.00 25.18  ? 425 TYR A CD2 1 
ATOM   3168  C CE1 . TYR A 1 425 ? 141.974 139.400 147.021 1.00 25.18  ? 425 TYR A CE1 1 
ATOM   3169  C CE2 . TYR A 1 425 ? 139.917 138.278 146.553 1.00 25.18  ? 425 TYR A CE2 1 
ATOM   3170  C CZ  . TYR A 1 425 ? 140.636 139.202 147.277 1.00 25.18  ? 425 TYR A CZ  1 
ATOM   3171  O OH  . TYR A 1 425 ? 140.015 139.930 148.262 1.00 25.18  ? 425 TYR A OH  1 
ATOM   3172  N N   . ASN A 1 426 ? 141.398 134.123 145.069 1.00 24.96  ? 426 ASN A N   1 
ATOM   3173  C CA  . ASN A 1 426 ? 140.482 133.327 145.882 1.00 24.96  ? 426 ASN A CA  1 
ATOM   3174  C C   . ASN A 1 426 ? 141.241 132.371 146.794 1.00 24.96  ? 426 ASN A C   1 
ATOM   3175  O O   . ASN A 1 426 ? 140.948 132.271 147.992 1.00 24.96  ? 426 ASN A O   1 
ATOM   3176  C CB  . ASN A 1 426 ? 139.519 132.546 144.987 1.00 24.96  ? 426 ASN A CB  1 
ATOM   3177  C CG  . ASN A 1 426 ? 138.325 133.365 144.551 1.00 24.96  ? 426 ASN A CG  1 
ATOM   3178  O OD1 . ASN A 1 426 ? 138.032 134.413 145.119 1.00 24.96  ? 426 ASN A OD1 1 
ATOM   3179  N ND2 . ASN A 1 426 ? 137.622 132.880 143.539 1.00 24.96  ? 426 ASN A ND2 1 
ATOM   3180  N N   . ALA A 1 427 ? 142.221 131.654 146.238 1.00 27.37  ? 427 ALA A N   1 
ATOM   3181  C CA  . ALA A 1 427 ? 142.958 130.672 147.030 1.00 27.37  ? 427 ALA A CA  1 
ATOM   3182  C C   . ALA A 1 427 ? 143.708 131.334 148.183 1.00 27.37  ? 427 ALA A C   1 
ATOM   3183  O O   . ALA A 1 427 ? 143.668 130.853 149.328 1.00 27.37  ? 427 ALA A O   1 
ATOM   3184  C CB  . ALA A 1 427 ? 143.922 129.894 146.135 1.00 27.37  ? 427 ALA A CB  1 
ATOM   3185  N N   . GLU A 1 428 ? 144.393 132.448 147.901 1.00 30.79  ? 428 GLU A N   1 
ATOM   3186  C CA  . GLU A 1 428 ? 145.138 133.139 148.955 1.00 30.79  ? 428 GLU A CA  1 
ATOM   3187  C C   . GLU A 1 428 ? 144.218 133.565 150.099 1.00 30.79  ? 428 GLU A C   1 
ATOM   3188  O O   . GLU A 1 428 ? 144.500 133.300 151.284 1.00 30.79  ? 428 GLU A O   1 
ATOM   3189  C CB  . GLU A 1 428 ? 145.864 134.350 148.365 1.00 30.79  ? 428 GLU A CB  1 
ATOM   3190  C CG  . GLU A 1 428 ? 146.868 135.009 149.294 1.00 30.79  ? 428 GLU A CG  1 
ATOM   3191  C CD  . GLU A 1 428 ? 148.104 134.160 149.515 1.00 30.79  ? 428 GLU A CD  1 
ATOM   3192  O OE1 . GLU A 1 428 ? 148.901 134.010 148.567 1.00 30.79  ? 428 GLU A OE1 1 
ATOM   3193  O OE2 . GLU A 1 428 ? 148.283 133.647 150.639 1.00 30.79  ? 428 GLU A OE2 1 
ATOM   3194  N N   . LEU A 1 429 ? 143.099 134.216 149.758 1.00 30.27  ? 429 LEU A N   1 
ATOM   3195  C CA  . LEU A 1 429 ? 142.187 134.689 150.796 1.00 30.27  ? 429 LEU A CA  1 
ATOM   3196  C C   . LEU A 1 429 ? 141.613 133.531 151.605 1.00 30.27  ? 429 LEU A C   1 
ATOM   3197  O O   . LEU A 1 429 ? 141.512 133.614 152.839 1.00 30.27  ? 429 LEU A O   1 
ATOM   3198  C CB  . LEU A 1 429 ? 141.062 135.516 150.174 1.00 30.27  ? 429 LEU A CB  1 
ATOM   3199  C CG  . LEU A 1 429 ? 139.995 136.026 151.146 1.00 30.27  ? 429 LEU A CG  1 
ATOM   3200  C CD1 . LEU A 1 429 ? 140.609 136.966 152.169 1.00 30.27  ? 429 LEU A CD1 1 
ATOM   3201  C CD2 . LEU A 1 429 ? 138.858 136.707 150.408 1.00 30.27  ? 429 LEU A CD2 1 
ATOM   3202  N N   . LEU A 1 430 ? 141.228 132.445 150.929 1.00 31.48  ? 430 LEU A N   1 
ATOM   3203  C CA  . LEU A 1 430 ? 140.635 131.314 151.631 1.00 31.48  ? 430 LEU A CA  1 
ATOM   3204  C C   . LEU A 1 430 ? 141.605 130.725 152.645 1.00 31.48  ? 430 LEU A C   1 
ATOM   3205  O O   . LEU A 1 430 ? 141.220 130.435 153.787 1.00 31.48  ? 430 LEU A O   1 
ATOM   3206  C CB  . LEU A 1 430 ? 140.196 130.244 150.632 1.00 31.48  ? 430 LEU A CB  1 
ATOM   3207  C CG  . LEU A 1 430 ? 139.681 128.942 151.247 1.00 31.48  ? 430 LEU A CG  1 
ATOM   3208  C CD1 . LEU A 1 430 ? 138.441 129.200 152.087 1.00 31.48  ? 430 LEU A CD1 1 
ATOM   3209  C CD2 . LEU A 1 430 ? 139.400 127.906 150.175 1.00 31.48  ? 430 LEU A CD2 1 
ATOM   3210  N N   . VAL A 1 431 ? 142.869 130.543 152.249 1.00 32.69  ? 431 VAL A N   1 
ATOM   3211  C CA  . VAL A 1 431 ? 143.837 129.963 153.176 1.00 32.69  ? 431 VAL A CA  1 
ATOM   3212  C C   . VAL A 1 431 ? 144.025 130.866 154.391 1.00 32.69  ? 431 VAL A C   1 
ATOM   3213  O O   . VAL A 1 431 ? 144.036 130.392 155.540 1.00 32.69  ? 431 VAL A O   1 
ATOM   3214  C CB  . VAL A 1 431 ? 145.171 129.679 152.460 1.00 32.69  ? 431 VAL A CB  1 
ATOM   3215  C CG1 . VAL A 1 431 ? 146.269 129.396 153.469 1.00 32.69  ? 431 VAL A CG1 1 
ATOM   3216  C CG2 . VAL A 1 431 ? 145.016 128.504 151.512 1.00 32.69  ? 431 VAL A CG2 1 
ATOM   3217  N N   . ALA A 1 432 ? 144.153 132.180 154.166 1.00 35.48  ? 432 ALA A N   1 
ATOM   3218  C CA  . ALA A 1 432 ? 144.352 133.089 155.296 1.00 35.48  ? 432 ALA A CA  1 
ATOM   3219  C C   . ALA A 1 432 ? 143.177 133.031 156.274 1.00 35.48  ? 432 ALA A C   1 
ATOM   3220  O O   . ALA A 1 432 ? 143.368 132.931 157.498 1.00 35.48  ? 432 ALA A O   1 
ATOM   3221  C CB  . ALA A 1 432 ? 144.566 134.514 154.792 1.00 35.48  ? 432 ALA A CB  1 
ATOM   3222  N N   . LEU A 1 433 ? 141.950 133.063 155.744 1.00 36.49  ? 433 LEU A N   1 
ATOM   3223  C CA  . LEU A 1 433 ? 140.761 133.038 156.596 1.00 36.49  ? 433 LEU A CA  1 
ATOM   3224  C C   . LEU A 1 433 ? 140.677 131.745 157.404 1.00 36.49  ? 433 LEU A C   1 
ATOM   3225  O O   . LEU A 1 433 ? 140.388 131.764 158.613 1.00 36.49  ? 433 LEU A O   1 
ATOM   3226  C CB  . LEU A 1 433 ? 139.508 133.204 155.738 1.00 36.49  ? 433 LEU A CB  1 
ATOM   3227  C CG  . LEU A 1 433 ? 138.904 134.596 155.605 1.00 36.49  ? 433 LEU A CG  1 
ATOM   3228  C CD1 . LEU A 1 433 ? 137.676 134.535 154.714 1.00 36.49  ? 433 LEU A CD1 1 
ATOM   3229  C CD2 . LEU A 1 433 ? 138.550 135.152 156.970 1.00 36.49  ? 433 LEU A CD2 1 
ATOM   3230  N N   . GLU A 1 434 ? 140.910 130.607 156.745 1.00 39.59  ? 434 GLU A N   1 
ATOM   3231  C CA  . GLU A 1 434 ? 140.795 129.327 157.434 1.00 39.59  ? 434 GLU A CA  1 
ATOM   3232  C C   . GLU A 1 434 ? 141.825 129.206 158.550 1.00 39.59  ? 434 GLU A C   1 
ATOM   3233  O O   . GLU A 1 434 ? 141.510 128.716 159.643 1.00 39.59  ? 434 GLU A O   1 
ATOM   3234  C CB  . GLU A 1 434 ? 140.935 128.178 156.437 1.00 39.59  ? 434 GLU A CB  1 
ATOM   3235  C CG  . GLU A 1 434 ? 139.808 128.110 155.422 1.00 39.59  ? 434 GLU A CG  1 
ATOM   3236  C CD  . GLU A 1 434 ? 138.617 127.317 155.914 1.00 39.59  ? 434 GLU A CD  1 
ATOM   3237  O OE1 . GLU A 1 434 ? 138.781 126.514 156.854 1.00 39.59  ? 434 GLU A OE1 1 
ATOM   3238  O OE2 . GLU A 1 434 ? 137.513 127.500 155.366 1.00 39.59  ? 434 GLU A OE2 1 
ATOM   3239  N N   . ASN A 1 435 ? 143.059 129.656 158.300 1.00 37.55  ? 435 ASN A N   1 
ATOM   3240  C CA  . ASN A 1 435 ? 144.077 129.597 159.345 1.00 37.55  ? 435 ASN A CA  1 
ATOM   3241  C C   . ASN A 1 435 ? 143.700 130.468 160.539 1.00 37.55  ? 435 ASN A C   1 
ATOM   3242  O O   . ASN A 1 435 ? 143.853 130.051 161.702 1.00 37.55  ? 435 ASN A O   1 
ATOM   3243  C CB  . ASN A 1 435 ? 145.431 130.016 158.777 1.00 37.55  ? 435 ASN A CB  1 
ATOM   3244  C CG  . ASN A 1 435 ? 146.054 128.942 157.910 1.00 37.55  ? 435 ASN A CG  1 
ATOM   3245  O OD1 . ASN A 1 435 ? 145.591 127.804 157.883 1.00 37.55  ? 435 ASN A OD1 1 
ATOM   3246  N ND2 . ASN A 1 435 ? 147.106 129.300 157.193 1.00 37.55  ? 435 ASN A ND2 1 
ATOM   3247  N N   . GLN A 1 436 ? 143.205 131.682 160.271 1.00 41.50  ? 436 GLN A N   1 
ATOM   3248  C CA  . GLN A 1 436 ? 142.760 132.555 161.354 1.00 41.50  ? 436 GLN A CA  1 
ATOM   3249  C C   . GLN A 1 436 ? 141.723 131.857 162.227 1.00 41.50  ? 436 GLN A C   1 
ATOM   3250  O O   . GLN A 1 436 ? 141.841 131.827 163.463 1.00 41.50  ? 436 GLN A O   1 
ATOM   3251  C CB  . GLN A 1 436 ? 142.193 133.849 160.772 1.00 41.50  ? 436 GLN A CB  1 
ATOM   3252  C CG  . GLN A 1 436 ? 141.597 134.798 161.798 1.00 41.50  ? 436 GLN A CG  1 
ATOM   3253  C CD  . GLN A 1 436 ? 142.639 135.673 162.462 1.00 41.50  ? 436 GLN A CD  1 
ATOM   3254  O OE1 . GLN A 1 436 ? 143.664 135.999 161.868 1.00 41.50  ? 436 GLN A OE1 1 
ATOM   3255  N NE2 . GLN A 1 436 ? 142.383 136.054 163.705 1.00 41.50  ? 436 GLN A NE2 1 
ATOM   3256  N N   . HIS A 1 437 ? 140.709 131.261 161.594 1.00 43.10  ? 437 HIS A N   1 
ATOM   3257  C CA  . HIS A 1 437 ? 139.643 130.642 162.377 1.00 43.10  ? 437 HIS A CA  1 
ATOM   3258  C C   . HIS A 1 437 ? 140.125 129.406 163.134 1.00 43.10  ? 437 HIS A C   1 
ATOM   3259  O O   . HIS A 1 437 ? 139.662 129.156 164.253 1.00 43.10  ? 437 HIS A O   1 
ATOM   3260  C CB  . HIS A 1 437 ? 138.455 130.313 161.480 1.00 43.10  ? 437 HIS A CB  1 
ATOM   3261  C CG  . HIS A 1 437 ? 137.561 131.486 161.229 1.00 43.10  ? 437 HIS A CG  1 
ATOM   3262  N ND1 . HIS A 1 437 ? 136.575 131.871 162.112 1.00 43.10  ? 437 HIS A ND1 1 
ATOM   3263  C CD2 . HIS A 1 437 ? 137.522 132.377 160.211 1.00 43.10  ? 437 HIS A CD2 1 
ATOM   3264  C CE1 . HIS A 1 437 ? 135.959 132.940 161.642 1.00 43.10  ? 437 HIS A CE1 1 
ATOM   3265  N NE2 . HIS A 1 437 ? 136.514 133.268 160.490 1.00 43.10  ? 437 HIS A NE2 1 
ATOM   3266  N N   . THR A 1 438 ? 141.050 128.632 162.560 1.00 44.85  ? 438 THR A N   1 
ATOM   3267  C CA  . THR A 1 438 ? 141.589 127.476 163.276 1.00 44.85  ? 438 THR A CA  1 
ATOM   3268  C C   . THR A 1 438 ? 142.300 127.901 164.558 1.00 44.85  ? 438 THR A C   1 
ATOM   3269  O O   . THR A 1 438 ? 142.077 127.322 165.637 1.00 44.85  ? 438 THR A O   1 
ATOM   3270  C CB  . THR A 1 438 ? 142.542 126.697 162.368 1.00 44.85  ? 438 THR A CB  1 
ATOM   3271  O OG1 . THR A 1 438 ? 141.803 126.090 161.304 1.00 44.85  ? 438 THR A OG1 1 
ATOM   3272  C CG2 . THR A 1 438 ? 143.272 125.616 163.150 1.00 44.85  ? 438 THR A CG2 1 
ATOM   3273  N N   . ILE A 1 439 ? 143.157 128.922 164.460 1.00 46.96  ? 439 ILE A N   1 
ATOM   3274  C CA  . ILE A 1 439 ? 143.871 129.397 165.644 1.00 46.96  ? 439 ILE A CA  1 
ATOM   3275  C C   . ILE A 1 439 ? 142.883 129.887 166.697 1.00 46.96  ? 439 ILE A C   1 
ATOM   3276  O O   . ILE A 1 439 ? 142.998 129.564 167.893 1.00 46.96  ? 439 ILE A O   1 
ATOM   3277  C CB  . ILE A 1 439 ? 144.879 130.494 165.260 1.00 46.96  ? 439 ILE A CB  1 
ATOM   3278  C CG1 . ILE A 1 439 ? 145.917 129.946 164.281 1.00 46.96  ? 439 ILE A CG1 1 
ATOM   3279  C CG2 . ILE A 1 439 ? 145.555 131.058 166.497 1.00 46.96  ? 439 ILE A CG2 1 
ATOM   3280  C CD1 . ILE A 1 439 ? 146.751 128.833 164.851 1.00 46.96  ? 439 ILE A CD1 1 
ATOM   3281  N N   . ASP A 1 440 ? 141.883 130.661 166.261 1.00 49.44  ? 440 ASP A N   1 
ATOM   3282  C CA  . ASP A 1 440 ? 140.898 131.183 167.202 1.00 49.44  ? 440 ASP A CA  1 
ATOM   3283  C C   . ASP A 1 440 ? 140.158 130.058 167.918 1.00 49.44  ? 440 ASP A C   1 
ATOM   3284  O O   . ASP A 1 440 ? 139.952 130.122 169.137 1.00 49.44  ? 440 ASP A O   1 
ATOM   3285  C CB  . ASP A 1 440 ? 139.912 132.097 166.477 1.00 49.44  ? 440 ASP A CB  1 
ATOM   3286  C CG  . ASP A 1 440 ? 140.505 133.453 166.158 1.00 49.44  ? 440 ASP A CG  1 
ATOM   3287  O OD1 . ASP A 1 440 ? 141.599 133.762 166.674 1.00 49.44  ? 440 ASP A OD1 1 
ATOM   3288  O OD2 . ASP A 1 440 ? 139.879 134.212 165.389 1.00 49.44  ? 440 ASP A OD2 1 
ATOM   3289  N N   . LEU A 1 441 ? 139.753 129.017 167.184 1.00 52.14  ? 441 LEU A N   1 
ATOM   3290  C CA  . LEU A 1 441 ? 138.981 127.948 167.812 1.00 52.14  ? 441 LEU A CA  1 
ATOM   3291  C C   . LEU A 1 441 ? 139.819 127.167 168.819 1.00 52.14  ? 441 LEU A C   1 
ATOM   3292  O O   . LEU A 1 441 ? 139.319 126.801 169.891 1.00 52.14  ? 441 LEU A O   1 
ATOM   3293  C CB  . LEU A 1 441 ? 138.378 127.021 166.750 1.00 52.14  ? 441 LEU A CB  1 
ATOM   3294  C CG  . LEU A 1 441 ? 139.166 125.927 166.022 1.00 52.14  ? 441 LEU A CG  1 
ATOM   3295  C CD1 . LEU A 1 441 ? 139.174 124.613 166.791 1.00 52.14  ? 441 LEU A CD1 1 
ATOM   3296  C CD2 . LEU A 1 441 ? 138.584 125.716 164.635 1.00 52.14  ? 441 LEU A CD2 1 
ATOM   3297  N N   . THR A 1 442 ? 141.093 126.903 168.508 1.00 53.87  ? 442 THR A N   1 
ATOM   3298  C CA  . THR A 1 442 ? 141.920 126.192 169.484 1.00 53.87  ? 442 THR A CA  1 
ATOM   3299  C C   . THR A 1 442 ? 142.105 127.012 170.762 1.00 53.87  ? 442 THR A C   1 
ATOM   3300  O O   . THR A 1 442 ? 141.987 126.481 171.883 1.00 53.87  ? 442 THR A O   1 
ATOM   3301  C CB  . THR A 1 442 ? 143.274 125.824 168.874 1.00 53.87  ? 442 THR A CB  1 
ATOM   3302  O OG1 . THR A 1 442 ? 143.805 126.946 168.160 1.00 53.87  ? 442 THR A OG1 1 
ATOM   3303  C CG2 . THR A 1 442 ? 143.126 124.648 167.926 1.00 53.87  ? 442 THR A CG2 1 
ATOM   3304  N N   . ASP A 1 443 ? 142.369 128.317 170.616 1.00 57.07  ? 443 ASP A N   1 
ATOM   3305  C CA  . ASP A 1 443 ? 142.515 129.162 171.799 1.00 57.07  ? 443 ASP A CA  1 
ATOM   3306  C C   . ASP A 1 443 ? 141.230 129.187 172.623 1.00 57.07  ? 443 ASP A C   1 
ATOM   3307  O O   . ASP A 1 443 ? 141.269 129.104 173.862 1.00 57.07  ? 443 ASP A O   1 
ATOM   3308  C CB  . ASP A 1 443 ? 142.914 130.578 171.389 1.00 57.07  ? 443 ASP A CB  1 
ATOM   3309  C CG  . ASP A 1 443 ? 144.356 130.670 170.940 1.00 57.07  ? 443 ASP A CG  1 
ATOM   3310  O OD1 . ASP A 1 443 ? 145.154 129.789 171.316 1.00 57.07  ? 443 ASP A OD1 1 
ATOM   3311  O OD2 . ASP A 1 443 ? 144.695 131.629 170.215 1.00 57.07  ? 443 ASP A OD2 1 
ATOM   3312  N N   . SER A 1 444 ? 140.081 129.293 171.950 1.00 59.69  ? 444 SER A N   1 
ATOM   3313  C CA  . SER A 1 444 ? 138.809 129.331 172.662 1.00 59.69  ? 444 SER A CA  1 
ATOM   3314  C C   . SER A 1 444 ? 138.549 128.027 173.404 1.00 59.69  ? 444 SER A C   1 
ATOM   3315  O O   . SER A 1 444 ? 138.013 128.039 174.516 1.00 59.69  ? 444 SER A O   1 
ATOM   3316  C CB  . SER A 1 444 ? 137.671 129.636 171.688 1.00 59.69  ? 444 SER A CB  1 
ATOM   3317  O OG  . SER A 1 444 ? 136.983 128.456 171.318 1.00 59.69  ? 444 SER A OG  1 
ATOM   3318  N N   . GLU A 1 445 ? 138.913 126.891 172.803 1.00 63.90  ? 445 GLU A N   1 
ATOM   3319  C CA  . GLU A 1 445 ? 138.752 125.609 173.484 1.00 63.90  ? 445 GLU A CA  1 
ATOM   3320  C C   . GLU A 1 445 ? 139.558 125.566 174.779 1.00 63.90  ? 445 GLU A C   1 
ATOM   3321  O O   . GLU A 1 445 ? 139.050 125.148 175.833 1.00 63.90  ? 445 GLU A O   1 
ATOM   3322  C CB  . GLU A 1 445 ? 139.170 124.469 172.556 1.00 63.90  ? 445 GLU A CB  1 
ATOM   3323  C CG  . GLU A 1 445 ? 138.469 123.148 172.822 1.00 63.90  ? 445 GLU A CG  1 
ATOM   3324  C CD  . GLU A 1 445 ? 136.974 123.219 172.588 1.00 63.90  ? 445 GLU A CD  1 
ATOM   3325  O OE1 . GLU A 1 445 ? 136.557 123.842 171.590 1.00 63.90  ? 445 GLU A OE1 1 
ATOM   3326  O OE2 . GLU A 1 445 ? 136.217 122.648 173.400 1.00 63.90  ? 445 GLU A OE2 1 
ATOM   3327  N N   . MET A 1 446 ? 140.824 125.992 174.718 1.00 65.34  ? 446 MET A N   1 
ATOM   3328  C CA  . MET A 1 446 ? 141.642 125.988 175.933 1.00 65.34  ? 446 MET A CA  1 
ATOM   3329  C C   . MET A 1 446 ? 141.031 126.881 177.011 1.00 65.34  ? 446 MET A C   1 
ATOM   3330  O O   . MET A 1 446 ? 140.937 126.493 178.189 1.00 65.34  ? 446 MET A O   1 
ATOM   3331  C CB  . MET A 1 446 ? 143.070 126.432 175.613 1.00 65.34  ? 446 MET A CB  1 
ATOM   3332  C CG  . MET A 1 446 ? 143.986 126.484 176.828 1.00 65.34  ? 446 MET A CG  1 
ATOM   3333  S SD  . MET A 1 446 ? 144.795 124.911 177.190 1.00 65.34  ? 446 MET A SD  1 
ATOM   3334  C CE  . MET A 1 446 ? 143.848 124.339 178.597 1.00 65.34  ? 446 MET A CE  1 
ATOM   3335  N N   . ASN A 1 447 ? 140.595 128.082 176.620 1.00 66.36  ? 447 ASN A N   1 
ATOM   3336  C CA  . ASN A 1 447 ? 140.014 129.004 177.593 1.00 66.36  ? 447 ASN A CA  1 
ATOM   3337  C C   . ASN A 1 447 ? 138.732 128.444 178.199 1.00 66.36  ? 447 ASN A C   1 
ATOM   3338  O O   . ASN A 1 447 ? 138.478 128.612 179.398 1.00 66.36  ? 447 ASN A O   1 
ATOM   3339  C CB  . ASN A 1 447 ? 139.754 130.359 176.940 1.00 66.36  ? 447 ASN A CB  1 
ATOM   3340  C CG  . ASN A 1 447 ? 140.999 131.211 176.866 1.00 66.36  ? 447 ASN A CG  1 
ATOM   3341  O OD1 . ASN A 1 447 ? 141.710 131.377 177.857 1.00 66.36  ? 447 ASN A OD1 1 
ATOM   3342  N ND2 . ASN A 1 447 ? 141.278 131.750 175.688 1.00 66.36  ? 447 ASN A ND2 1 
ATOM   3343  N N   . LYS A 1 448 ? 137.908 127.785 177.383 1.00 68.41  ? 448 LYS A N   1 
ATOM   3344  C CA  . LYS A 1 448 ? 136.675 127.195 177.891 1.00 68.41  ? 448 LYS A CA  1 
ATOM   3345  C C   . LYS A 1 448 ? 136.966 126.112 178.920 1.00 68.41  ? 448 LYS A C   1 
ATOM   3346  O O   . LYS A 1 448 ? 136.287 126.029 179.951 1.00 68.41  ? 448 LYS A O   1 
ATOM   3347  C CB  . LYS A 1 448 ? 135.853 126.623 176.738 1.00 68.41  ? 448 LYS A CB  1 
ATOM   3348  C CG  . LYS A 1 448 ? 134.804 127.571 176.189 1.00 68.41  ? 448 LYS A CG  1 
ATOM   3349  C CD  . LYS A 1 448 ? 134.291 127.111 174.832 1.00 68.41  ? 448 LYS A CD  1 
ATOM   3350  C CE  . LYS A 1 448 ? 134.299 125.594 174.711 1.00 68.41  ? 448 LYS A CE  1 
ATOM   3351  N NZ  . LYS A 1 448 ? 134.357 125.146 173.291 1.00 68.41  ? 448 LYS A NZ  1 
ATOM   3352  N N   . LEU A 1 449 ? 137.964 125.265 178.653 1.00 71.36  ? 449 LEU A N   1 
ATOM   3353  C CA  . LEU A 1 449 ? 138.317 124.242 179.636 1.00 71.36  ? 449 LEU A CA  1 
ATOM   3354  C C   . LEU A 1 449 ? 138.761 124.875 180.951 1.00 71.36  ? 449 LEU A C   1 
ATOM   3355  O O   . LEU A 1 449 ? 138.338 124.442 182.036 1.00 71.36  ? 449 LEU A O   1 
ATOM   3356  C CB  . LEU A 1 449 ? 139.410 123.327 179.085 1.00 71.36  ? 449 LEU A CB  1 
ATOM   3357  C CG  . LEU A 1 449 ? 139.797 122.155 179.989 1.00 71.36  ? 449 LEU A CG  1 
ATOM   3358  C CD1 . LEU A 1 449 ? 138.568 121.358 180.401 1.00 71.36  ? 449 LEU A CD1 1 
ATOM   3359  C CD2 . LEU A 1 449 ? 140.819 121.261 179.312 1.00 71.36  ? 449 LEU A CD2 1 
ATOM   3360  N N   . PHE A 1 450 ? 139.601 125.912 180.876 1.00 75.81  ? 450 PHE A N   1 
ATOM   3361  C CA  . PHE A 1 450 ? 140.044 126.566 182.106 1.00 75.81  ? 450 PHE A CA  1 
ATOM   3362  C C   . PHE A 1 450 ? 138.870 127.174 182.869 1.00 75.81  ? 450 PHE A C   1 
ATOM   3363  O O   . PHE A 1 450 ? 138.792 127.061 184.099 1.00 75.81  ? 450 PHE A O   1 
ATOM   3364  C CB  . PHE A 1 450 ? 141.087 127.638 181.803 1.00 75.81  ? 450 PHE A CB  1 
ATOM   3365  C CG  . PHE A 1 450 ? 141.690 128.253 183.033 1.00 75.81  ? 450 PHE A CG  1 
ATOM   3366  C CD1 . PHE A 1 450 ? 142.677 127.590 183.740 1.00 75.81  ? 450 PHE A CD1 1 
ATOM   3367  C CD2 . PHE A 1 450 ? 141.260 129.487 183.490 1.00 75.81  ? 450 PHE A CD2 1 
ATOM   3368  C CE1 . PHE A 1 450 ? 143.232 128.150 184.873 1.00 75.81  ? 450 PHE A CE1 1 
ATOM   3369  C CE2 . PHE A 1 450 ? 141.811 130.050 184.622 1.00 75.81  ? 450 PHE A CE2 1 
ATOM   3370  C CZ  . PHE A 1 450 ? 142.798 129.381 185.314 1.00 75.81  ? 450 PHE A CZ  1 
ATOM   3371  N N   . GLU A 1 451 ? 137.945 127.822 182.156 1.00 77.33  ? 451 GLU A N   1 
ATOM   3372  C CA  . GLU A 1 451 ? 136.811 128.455 182.825 1.00 77.33  ? 451 GLU A CA  1 
ATOM   3373  C C   . GLU A 1 451 ? 135.885 127.423 183.457 1.00 77.33  ? 451 GLU A C   1 
ATOM   3374  O O   . GLU A 1 451 ? 135.330 127.660 184.535 1.00 77.33  ? 451 GLU A O   1 
ATOM   3375  C CB  . GLU A 1 451 ? 136.042 129.338 181.845 1.00 77.33  ? 451 GLU A CB  1 
ATOM   3376  C CG  . GLU A 1 451 ? 135.633 130.680 182.430 1.00 77.33  ? 451 GLU A CG  1 
ATOM   3377  C CD  . GLU A 1 451 ? 136.745 131.338 183.228 1.00 77.33  ? 451 GLU A CD  1 
ATOM   3378  O OE1 . GLU A 1 451 ? 137.877 131.442 182.708 1.00 77.33  ? 451 GLU A OE1 1 
ATOM   3379  O OE2 . GLU A 1 451 ? 136.487 131.750 184.379 1.00 77.33  ? 451 GLU A OE2 1 
ATOM   3380  N N   . LYS A 1 452 ? 135.693 126.280 182.799 1.00 78.81  ? 452 LYS A N   1 
ATOM   3381  C CA  . LYS A 1 452 ? 134.887 125.218 183.392 1.00 78.81  ? 452 LYS A CA  1 
ATOM   3382  C C   . LYS A 1 452 ? 135.522 124.707 184.680 1.00 78.81  ? 452 LYS A C   1 
ATOM   3383  O O   . LYS A 1 452 ? 134.839 124.517 185.698 1.00 78.81  ? 452 LYS A O   1 
ATOM   3384  C CB  . LYS A 1 452 ? 134.709 124.080 182.390 1.00 78.81  ? 452 LYS A CB  1 
ATOM   3385  C CG  . LYS A 1 452 ? 133.480 123.232 182.622 1.00 78.81  ? 452 LYS A CG  1 
ATOM   3386  C CD  . LYS A 1 452 ? 133.335 122.192 181.532 1.00 78.81  ? 452 LYS A CD  1 
ATOM   3387  C CE  . LYS A 1 452 ? 134.041 120.904 181.907 1.00 78.81  ? 452 LYS A CE  1 
ATOM   3388  N NZ  . LYS A 1 452 ? 133.188 120.035 182.761 1.00 78.81  ? 452 LYS A NZ  1 
ATOM   3389  N N   . THR A 1 453 ? 136.842 124.491 184.656 1.00 80.45  ? 453 THR A N   1 
ATOM   3390  C CA  . THR A 1 453 ? 137.528 124.064 185.872 1.00 80.45  ? 453 THR A CA  1 
ATOM   3391  C C   . THR A 1 453 ? 137.380 125.104 186.977 1.00 80.45  ? 453 THR A C   1 
ATOM   3392  O O   . THR A 1 453 ? 137.189 124.754 188.148 1.00 80.45  ? 453 THR A O   1 
ATOM   3393  C CB  . THR A 1 453 ? 139.003 123.791 185.584 1.00 80.45  ? 453 THR A CB  1 
ATOM   3394  O OG1 . THR A 1 453 ? 139.113 122.768 184.588 1.00 80.45  ? 453 THR A OG1 1 
ATOM   3395  C CG2 . THR A 1 453 ? 139.716 123.332 186.845 1.00 80.45  ? 453 THR A CG2 1 
ATOM   3396  N N   . ARG A 1 454 ? 137.456 126.389 186.623 1.00 82.36  ? 454 ARG A N   1 
ATOM   3397  C CA  . ARG A 1 454 ? 137.238 127.438 187.617 1.00 82.36  ? 454 ARG A CA  1 
ATOM   3398  C C   . ARG A 1 454 ? 135.823 127.385 188.180 1.00 82.36  ? 454 ARG A C   1 
ATOM   3399  O O   . ARG A 1 454 ? 135.615 127.604 189.378 1.00 82.36  ? 454 ARG A O   1 
ATOM   3400  C CB  . ARG A 1 454 ? 137.512 128.813 187.014 1.00 82.36  ? 454 ARG A CB  1 
ATOM   3401  C CG  . ARG A 1 454 ? 137.712 129.899 188.056 1.00 82.36  ? 454 ARG A CG  1 
ATOM   3402  C CD  . ARG A 1 454 ? 137.688 131.276 187.426 1.00 82.36  ? 454 ARG A CD  1 
ATOM   3403  N NE  . ARG A 1 454 ? 138.942 131.989 187.633 1.00 82.36  ? 454 ARG A NE  1 
ATOM   3404  C CZ  . ARG A 1 454 ? 139.619 132.603 186.673 1.00 82.36  ? 454 ARG A CZ  1 
ATOM   3405  N NH1 . ARG A 1 454 ? 139.197 132.601 185.420 1.00 82.36  ? 454 ARG A NH1 1 
ATOM   3406  N NH2 . ARG A 1 454 ? 140.750 133.231 186.978 1.00 82.36  ? 454 ARG A NH2 1 
ATOM   3407  N N   . ARG A 1 455 ? 134.835 127.113 187.325 1.00 85.06  ? 455 ARG A N   1 
ATOM   3408  C CA  . ARG A 1 455 ? 133.456 127.013 187.795 1.00 85.06  ? 455 ARG A CA  1 
ATOM   3409  C C   . ARG A 1 455 ? 133.295 125.884 188.802 1.00 85.06  ? 455 ARG A C   1 
ATOM   3410  O O   . ARG A 1 455 ? 132.580 126.033 189.800 1.00 85.06  ? 455 ARG A O   1 
ATOM   3411  C CB  . ARG A 1 455 ? 132.500 126.803 186.620 1.00 85.06  ? 455 ARG A CB  1 
ATOM   3412  C CG  . ARG A 1 455 ? 132.177 128.056 185.832 1.00 85.06  ? 455 ARG A CG  1 
ATOM   3413  C CD  . ARG A 1 455 ? 130.951 127.846 184.960 1.00 85.06  ? 455 ARG A CD  1 
ATOM   3414  N NE  . ARG A 1 455 ? 131.218 128.131 183.556 1.00 85.06  ? 455 ARG A NE  1 
ATOM   3415  C CZ  . ARG A 1 455 ? 131.096 127.246 182.576 1.00 85.06  ? 455 ARG A CZ  1 
ATOM   3416  N NH1 . ARG A 1 455 ? 130.684 126.010 182.808 1.00 85.06  ? 455 ARG A NH1 1 
ATOM   3417  N NH2 . ARG A 1 455 ? 131.391 127.611 181.332 1.00 85.06  ? 455 ARG A NH2 1 
ATOM   3418  N N   . GLN A 1 456 ? 133.936 124.738 188.551 1.00 88.44  ? 456 GLN A N   1 
ATOM   3419  C CA  . GLN A 1 456 ? 133.766 123.602 189.456 1.00 88.44  ? 456 GLN A CA  1 
ATOM   3420  C C   . GLN A 1 456 ? 134.272 123.919 190.860 1.00 88.44  ? 456 GLN A C   1 
ATOM   3421  O O   . GLN A 1 456 ? 133.623 123.569 191.852 1.00 88.44  ? 456 GLN A O   1 
ATOM   3422  C CB  . GLN A 1 456 ? 134.470 122.367 188.900 1.00 88.44  ? 456 GLN A CB  1 
ATOM   3423  C CG  . GLN A 1 456 ? 133.694 121.665 187.808 1.00 88.44  ? 456 GLN A CG  1 
ATOM   3424  C CD  . GLN A 1 456 ? 134.161 120.243 187.593 1.00 88.44  ? 456 GLN A CD  1 
ATOM   3425  O OE1 . GLN A 1 456 ? 134.435 119.830 186.468 1.00 88.44  ? 456 GLN A OE1 1 
ATOM   3426  N NE2 . GLN A 1 456 ? 134.250 119.481 188.675 1.00 88.44  ? 456 GLN A NE2 1 
ATOM   3427  N N   . LEU A 1 457 ? 135.423 124.575 190.966 1.00 89.80  ? 457 LEU A N   1 
ATOM   3428  C CA  . LEU A 1 457 ? 135.968 124.977 192.262 1.00 89.80  ? 457 LEU A CA  1 
ATOM   3429  C C   . LEU A 1 457 ? 135.310 126.291 192.665 1.00 89.80  ? 457 LEU A C   1 
ATOM   3430  O O   . LEU A 1 457 ? 135.679 127.361 192.178 1.00 89.80  ? 457 LEU A O   1 
ATOM   3431  C CB  . LEU A 1 457 ? 137.484 125.108 192.188 1.00 89.80  ? 457 LEU A CB  1 
ATOM   3432  C CG  . LEU A 1 457 ? 138.251 123.848 191.776 1.00 89.80  ? 457 LEU A CG  1 
ATOM   3433  C CD1 . LEU A 1 457 ? 139.528 124.220 191.045 1.00 89.80  ? 457 LEU A CD1 1 
ATOM   3434  C CD2 . LEU A 1 457 ? 138.556 122.976 192.980 1.00 89.80  ? 457 LEU A CD2 1 
ATOM   3435  N N   . ARG A 1 458 ? 134.334 126.213 193.568 1.00 94.34  ? 458 ARG A N   1 
ATOM   3436  C CA  . ARG A 1 458 ? 133.457 127.351 193.829 1.00 94.34  ? 458 ARG A CA  1 
ATOM   3437  C C   . ARG A 1 458 ? 134.138 128.395 194.712 1.00 94.34  ? 458 ARG A C   1 
ATOM   3438  O O   . ARG A 1 458 ? 134.322 129.544 194.298 1.00 94.34  ? 458 ARG A O   1 
ATOM   3439  C CB  . ARG A 1 458 ? 132.151 126.841 194.445 1.00 94.34  ? 458 ARG A CB  1 
ATOM   3440  C CG  . ARG A 1 458 ? 131.105 126.511 193.386 1.00 94.34  ? 458 ARG A CG  1 
ATOM   3441  C CD  . ARG A 1 458 ? 129.662 126.662 193.849 1.00 94.34  ? 458 ARG A CD  1 
ATOM   3442  N NE  . ARG A 1 458 ? 129.373 127.894 194.570 1.00 94.34  ? 458 ARG A NE  1 
ATOM   3443  C CZ  . ARG A 1 458 ? 128.330 128.045 195.376 1.00 94.34  ? 458 ARG A CZ  1 
ATOM   3444  N NH1 . ARG A 1 458 ? 127.467 127.063 195.580 1.00 94.34  ? 458 ARG A NH1 1 
ATOM   3445  N NH2 . ARG A 1 458 ? 128.144 129.209 195.988 1.00 94.34  ? 458 ARG A NH2 1 
ATOM   3446  N N   . GLU A 1 459 ? 134.530 128.013 195.931 1.00 96.88  ? 459 GLU A N   1 
ATOM   3447  C CA  . GLU A 1 459 ? 135.277 128.907 196.808 1.00 96.88  ? 459 GLU A CA  1 
ATOM   3448  C C   . GLU A 1 459 ? 136.532 128.287 197.405 1.00 96.88  ? 459 GLU A C   1 
ATOM   3449  O O   . GLU A 1 459 ? 137.246 128.977 198.142 1.00 96.88  ? 459 GLU A O   1 
ATOM   3450  C CB  . GLU A 1 459 ? 134.389 129.415 197.955 1.00 96.88  ? 459 GLU A CB  1 
ATOM   3451  C CG  . GLU A 1 459 ? 133.433 130.526 197.565 1.00 96.88  ? 459 GLU A CG  1 
ATOM   3452  C CD  . GLU A 1 459 ? 134.146 131.790 197.121 1.00 96.88  ? 459 GLU A CD  1 
ATOM   3453  O OE1 . GLU A 1 459 ? 133.527 132.596 196.395 1.00 96.88  ? 459 GLU A OE1 1 
ATOM   3454  O OE2 . GLU A 1 459 ? 135.318 131.988 197.508 1.00 96.88  ? 459 GLU A OE2 1 
ATOM   3455  N N   . ASN A 1 460 ? 136.829 127.026 197.111 1.00 97.22  ? 460 ASN A N   1 
ATOM   3456  C CA  . ASN A 1 460 ? 137.937 126.326 197.748 1.00 97.22  ? 460 ASN A CA  1 
ATOM   3457  C C   . ASN A 1 460 ? 139.256 126.470 197.001 1.00 97.22  ? 460 ASN A C   1 
ATOM   3458  O O   . ASN A 1 460 ? 140.252 125.871 197.421 1.00 97.22  ? 460 ASN A O   1 
ATOM   3459  C CB  . ASN A 1 460 ? 137.597 124.841 197.901 1.00 97.22  ? 460 ASN A CB  1 
ATOM   3460  C CG  . ASN A 1 460 ? 136.110 124.597 198.050 1.00 97.22  ? 460 ASN A CG  1 
ATOM   3461  O OD1 . ASN A 1 460 ? 135.458 124.097 197.136 1.00 97.22  ? 460 ASN A OD1 1 
ATOM   3462  N ND2 . ASN A 1 460 ? 135.565 124.951 199.206 1.00 97.22  ? 460 ASN A ND2 1 
ATOM   3463  N N   . ALA A 1 461 ? 139.299 127.242 195.918 1.00 95.27  ? 461 ALA A N   1 
ATOM   3464  C CA  . ALA A 1 461 ? 140.497 127.335 195.098 1.00 95.27  ? 461 ALA A CA  1 
ATOM   3465  C C   . ALA A 1 461 ? 140.775 128.786 194.737 1.00 95.27  ? 461 ALA A C   1 
ATOM   3466  O O   . ALA A 1 461 ? 139.881 129.634 194.737 1.00 95.27  ? 461 ALA A O   1 
ATOM   3467  C CB  . ALA A 1 461 ? 140.376 126.493 193.822 1.00 95.27  ? 461 ALA A CB  1 
ATOM   3468  N N   . GLU A 1 462 ? 142.041 129.055 194.425 1.00 94.33  ? 462 GLU A N   1 
ATOM   3469  C CA  . GLU A 1 462 ? 142.498 130.382 194.041 1.00 94.33  ? 462 GLU A CA  1 
ATOM   3470  C C   . GLU A 1 462 ? 143.267 130.308 192.728 1.00 94.33  ? 462 GLU A C   1 
ATOM   3471  O O   . GLU A 1 462 ? 144.038 129.375 192.493 1.00 94.33  ? 462 GLU A O   1 
ATOM   3472  C CB  . GLU A 1 462 ? 143.384 131.002 195.126 1.00 94.33  ? 462 GLU A CB  1 
ATOM   3473  C CG  . GLU A 1 462 ? 143.441 132.516 195.092 1.00 94.33  ? 462 GLU A CG  1 
ATOM   3474  C CD  . GLU A 1 462 ? 143.756 133.119 196.448 1.00 94.33  ? 462 GLU A CD  1 
ATOM   3475  O OE1 . GLU A 1 462 ? 143.509 132.450 197.473 1.00 94.33  ? 462 GLU A OE1 1 
ATOM   3476  O OE2 . GLU A 1 462 ? 144.269 134.256 196.487 1.00 94.33  ? 462 GLU A OE2 1 
ATOM   3477  N N   . ASP A 1 463 ? 143.057 131.309 191.878 1.00 89.28  ? 463 ASP A N   1 
ATOM   3478  C CA  . ASP A 1 463 ? 143.729 131.390 190.586 1.00 89.28  ? 463 ASP A CA  1 
ATOM   3479  C C   . ASP A 1 463 ? 145.115 131.995 190.781 1.00 89.28  ? 463 ASP A C   1 
ATOM   3480  O O   . ASP A 1 463 ? 145.240 133.156 191.184 1.00 89.28  ? 463 ASP A O   1 
ATOM   3481  C CB  . ASP A 1 463 ? 142.906 132.222 189.603 1.00 89.28  ? 463 ASP A CB  1 
ATOM   3482  C CG  . ASP A 1 463 ? 143.524 132.278 188.215 1.00 89.28  ? 463 ASP A CG  1 
ATOM   3483  O OD1 . ASP A 1 463 ? 144.525 131.574 187.969 1.00 89.28  ? 463 ASP A OD1 1 
ATOM   3484  O OD2 . ASP A 1 463 ? 143.005 133.032 187.366 1.00 89.28  ? 463 ASP A OD2 1 
ATOM   3485  N N   . MET A 1 464 ? 146.152 131.211 190.490 1.00 89.12  ? 464 MET A N   1 
ATOM   3486  C CA  . MET A 1 464 ? 147.523 131.676 190.648 1.00 89.12  ? 464 MET A CA  1 
ATOM   3487  C C   . MET A 1 464 ? 147.957 132.644 189.556 1.00 89.12  ? 464 MET A C   1 
ATOM   3488  O O   . MET A 1 464 ? 149.015 133.268 189.692 1.00 89.12  ? 464 MET A O   1 
ATOM   3489  C CB  . MET A 1 464 ? 148.485 130.486 190.682 1.00 89.12  ? 464 MET A CB  1 
ATOM   3490  C CG  . MET A 1 464 ? 148.709 129.917 192.071 1.00 89.12  ? 464 MET A CG  1 
ATOM   3491  S SD  . MET A 1 464 ? 148.667 128.117 192.100 1.00 89.12  ? 464 MET A SD  1 
ATOM   3492  C CE  . MET A 1 464 ? 150.196 127.735 191.251 1.00 89.12  ? 464 MET A CE  1 
ATOM   3493  N N   . GLY A 1 465 ? 147.179 132.787 188.487 1.00 87.36  ? 465 GLY A N   1 
ATOM   3494  C CA  . GLY A 1 465 ? 147.515 133.696 187.413 1.00 87.36  ? 465 GLY A CA  1 
ATOM   3495  C C   . GLY A 1 465 ? 148.453 133.141 186.365 1.00 87.36  ? 465 GLY A C   1 
ATOM   3496  O O   . GLY A 1 465 ? 148.815 133.871 185.434 1.00 87.36  ? 465 GLY A O   1 
ATOM   3497  N N   . ASN A 1 466 ? 148.862 131.878 186.486 1.00 85.28  ? 466 ASN A N   1 
ATOM   3498  C CA  . ASN A 1 466 ? 149.704 131.216 185.499 1.00 85.28  ? 466 ASN A CA  1 
ATOM   3499  C C   . ASN A 1 466 ? 148.989 130.050 184.828 1.00 85.28  ? 466 ASN A C   1 
ATOM   3500  O O   . ASN A 1 466 ? 149.644 129.131 184.329 1.00 85.28  ? 466 ASN A O   1 
ATOM   3501  C CB  . ASN A 1 466 ? 151.002 130.734 186.148 1.00 85.28  ? 466 ASN A CB  1 
ATOM   3502  C CG  . ASN A 1 466 ? 152.216 131.497 185.661 1.00 85.28  ? 466 ASN A CG  1 
ATOM   3503  O OD1 . ASN A 1 466 ? 152.095 132.478 184.926 1.00 85.28  ? 466 ASN A OD1 1 
ATOM   3504  N ND2 . ASN A 1 466 ? 153.397 131.049 186.067 1.00 85.28  ? 466 ASN A ND2 1 
ATOM   3505  N N   . GLY A 1 467 ? 147.659 130.068 184.808 1.00 81.84  ? 467 GLY A N   1 
ATOM   3506  C CA  . GLY A 1 467 ? 146.896 128.930 184.342 1.00 81.84  ? 467 GLY A CA  1 
ATOM   3507  C C   . GLY A 1 467 ? 146.768 127.806 185.342 1.00 81.84  ? 467 GLY A C   1 
ATOM   3508  O O   . GLY A 1 467 ? 146.410 126.689 184.952 1.00 81.84  ? 467 GLY A O   1 
ATOM   3509  N N   . CYS A 1 468 ? 147.039 128.066 186.620 1.00 85.06  ? 468 CYS A N   1 
ATOM   3510  C CA  . CYS A 1 468 ? 147.056 127.040 187.650 1.00 85.06  ? 468 CYS A CA  1 
ATOM   3511  C C   . CYS A 1 468 ? 146.147 127.449 188.801 1.00 85.06  ? 468 CYS A C   1 
ATOM   3512  O O   . CYS A 1 468 ? 145.970 128.637 189.082 1.00 85.06  ? 468 CYS A O   1 
ATOM   3513  C CB  . CYS A 1 468 ? 148.476 126.810 188.175 1.00 85.06  ? 468 CYS A CB  1 
ATOM   3514  S SG  . CYS A 1 468 ? 149.594 126.032 186.994 1.00 85.06  ? 468 CYS A SG  1 
ATOM   3515  N N   . PHE A 1 469 ? 145.576 126.450 189.467 1.00 85.67  ? 469 PHE A N   1 
ATOM   3516  C CA  . PHE A 1 469 ? 144.710 126.637 190.619 1.00 85.67  ? 469 PHE A CA  1 
ATOM   3517  C C   . PHE A 1 469 ? 145.382 126.072 191.862 1.00 85.67  ? 469 PHE A C   1 
ATOM   3518  O O   . PHE A 1 469 ? 145.951 124.975 191.829 1.00 85.67  ? 469 PHE A O   1 
ATOM   3519  C CB  . PHE A 1 469 ? 143.362 125.940 190.414 1.00 85.67  ? 469 PHE A CB  1 
ATOM   3520  C CG  . PHE A 1 469 ? 142.446 126.652 189.467 1.00 85.67  ? 469 PHE A CG  1 
ATOM   3521  C CD1 . PHE A 1 469 ? 141.946 127.903 189.774 1.00 85.67  ? 469 PHE A CD1 1 
ATOM   3522  C CD2 . PHE A 1 469 ? 142.081 126.065 188.267 1.00 85.67  ? 469 PHE A CD2 1 
ATOM   3523  C CE1 . PHE A 1 469 ? 141.102 128.556 188.904 1.00 85.67  ? 469 PHE A CE1 1 
ATOM   3524  C CE2 . PHE A 1 469 ? 141.239 126.713 187.393 1.00 85.67  ? 469 PHE A CE2 1 
ATOM   3525  C CZ  . PHE A 1 469 ? 140.750 127.961 187.712 1.00 85.67  ? 469 PHE A CZ  1 
ATOM   3526  N N   . LYS A 1 470 ? 145.310 126.825 192.954 1.00 92.11  ? 470 LYS A N   1 
ATOM   3527  C CA  . LYS A 1 470 ? 145.769 126.378 194.262 1.00 92.11  ? 470 LYS A CA  1 
ATOM   3528  C C   . LYS A 1 470 ? 144.548 125.986 195.080 1.00 92.11  ? 470 LYS A C   1 
ATOM   3529  O O   . LYS A 1 470 ? 143.662 126.815 195.310 1.00 92.11  ? 470 LYS A O   1 
ATOM   3530  C CB  . LYS A 1 470 ? 146.566 127.475 194.967 1.00 92.11  ? 470 LYS A CB  1 
ATOM   3531  C CG  . LYS A 1 470 ? 147.480 126.972 196.065 1.00 92.11  ? 470 LYS A CG  1 
ATOM   3532  C CD  . LYS A 1 470 ? 147.849 128.087 197.029 1.00 92.11  ? 470 LYS A CD  1 
ATOM   3533  C CE  . LYS A 1 470 ? 148.715 129.136 196.352 1.00 92.11  ? 470 LYS A CE  1 
ATOM   3534  N NZ  . LYS A 1 470 ? 149.332 130.067 197.334 1.00 92.11  ? 470 LYS A NZ  1 
ATOM   3535  N N   . ILE A 1 471 ? 144.497 124.726 195.504 1.00 94.33  ? 471 ILE A N   1 
ATOM   3536  C CA  . ILE A 1 471 ? 143.390 124.193 196.289 1.00 94.33  ? 471 ILE A CA  1 
ATOM   3537  C C   . ILE A 1 471 ? 143.823 124.173 197.747 1.00 94.33  ? 471 ILE A C   1 
ATOM   3538  O O   . ILE A 1 471 ? 144.845 123.565 198.090 1.00 94.33  ? 471 ILE A O   1 
ATOM   3539  C CB  . ILE A 1 471 ? 142.987 122.790 195.808 1.00 94.33  ? 471 ILE A CB  1 
ATOM   3540  C CG1 . ILE A 1 471 ? 142.955 122.741 194.280 1.00 94.33  ? 471 ILE A CG1 1 
ATOM   3541  C CG2 . ILE A 1 471 ? 141.640 122.397 196.383 1.00 94.33  ? 471 ILE A CG2 1 
ATOM   3542  C CD1 . ILE A 1 471 ? 142.331 121.485 193.723 1.00 94.33  ? 471 ILE A CD1 1 
ATOM   3543  N N   . TYR A 1 472 ? 143.047 124.827 198.606 1.00 97.55  ? 472 TYR A N   1 
ATOM   3544  C CA  . TYR A 1 472 ? 143.445 125.070 199.985 1.00 97.55  ? 472 TYR A CA  1 
ATOM   3545  C C   . TYR A 1 472 ? 142.954 124.000 200.953 1.00 97.55  ? 472 TYR A C   1 
ATOM   3546  O O   . TYR A 1 472 ? 143.078 124.181 202.168 1.00 97.55  ? 472 TYR A O   1 
ATOM   3547  C CB  . TYR A 1 472 ? 142.958 126.451 200.433 1.00 97.55  ? 472 TYR A CB  1 
ATOM   3548  C CG  . TYR A 1 472 ? 143.850 127.575 199.955 1.00 97.55  ? 472 TYR A CG  1 
ATOM   3549  C CD1 . TYR A 1 472 ? 144.950 127.977 200.701 1.00 97.55  ? 472 TYR A CD1 1 
ATOM   3550  C CD2 . TYR A 1 472 ? 143.602 128.222 198.753 1.00 97.55  ? 472 TYR A CD2 1 
ATOM   3551  C CE1 . TYR A 1 472 ? 145.772 128.998 200.266 1.00 97.55  ? 472 TYR A CE1 1 
ATOM   3552  C CE2 . TYR A 1 472 ? 144.419 129.244 198.310 1.00 97.55  ? 472 TYR A CE2 1 
ATOM   3553  C CZ  . TYR A 1 472 ? 145.502 129.628 199.070 1.00 97.55  ? 472 TYR A CZ  1 
ATOM   3554  O OH  . TYR A 1 472 ? 146.319 130.646 198.634 1.00 97.55  ? 472 TYR A OH  1 
ATOM   3555  N N   . HIS A 1 473 ? 142.406 122.900 200.455 1.00 98.23  ? 473 HIS A N   1 
ATOM   3556  C CA  . HIS A 1 473 ? 142.082 121.748 201.283 1.00 98.23  ? 473 HIS A CA  1 
ATOM   3557  C C   . HIS A 1 473 ? 142.881 120.546 200.792 1.00 98.23  ? 473 HIS A C   1 
ATOM   3558  O O   . HIS A 1 473 ? 143.615 120.621 199.804 1.00 98.23  ? 473 HIS A O   1 
ATOM   3559  C CB  . HIS A 1 473 ? 140.577 121.461 201.277 1.00 98.23  ? 473 HIS A CB  1 
ATOM   3560  C CG  . HIS A 1 473 ? 140.064 120.901 199.987 1.00 98.23  ? 473 HIS A CG  1 
ATOM   3561  N ND1 . HIS A 1 473 ? 140.221 119.578 199.635 1.00 98.23  ? 473 HIS A ND1 1 
ATOM   3562  C CD2 . HIS A 1 473 ? 139.415 121.489 198.954 1.00 98.23  ? 473 HIS A CD2 1 
ATOM   3563  C CE1 . HIS A 1 473 ? 139.684 119.374 198.446 1.00 98.23  ? 473 HIS A CE1 1 
ATOM   3564  N NE2 . HIS A 1 473 ? 139.186 120.517 198.012 1.00 98.23  ? 473 HIS A NE2 1 
ATOM   3565  N N   . LYS A 1 474 ? 142.736 119.427 201.495 1.00 98.61  ? 474 LYS A N   1 
ATOM   3566  C CA  . LYS A 1 474 ? 143.474 118.213 201.158 1.00 98.61  ? 474 LYS A CA  1 
ATOM   3567  C C   . LYS A 1 474 ? 142.755 117.513 200.012 1.00 98.61  ? 474 LYS A C   1 
ATOM   3568  O O   . LYS A 1 474 ? 141.717 116.878 200.205 1.00 98.61  ? 474 LYS A O   1 
ATOM   3569  C CB  . LYS A 1 474 ? 143.607 117.305 202.374 1.00 98.61  ? 474 LYS A CB  1 
ATOM   3570  C CG  . LYS A 1 474 ? 144.828 116.407 202.329 1.00 98.61  ? 474 LYS A CG  1 
ATOM   3571  C CD  . LYS A 1 474 ? 145.434 116.235 203.712 1.00 98.61  ? 474 LYS A CD  1 
ATOM   3572  C CE  . LYS A 1 474 ? 146.321 117.416 204.074 1.00 98.61  ? 474 LYS A CE  1 
ATOM   3573  N NZ  . LYS A 1 474 ? 147.665 117.322 203.443 1.00 98.61  ? 474 LYS A NZ  1 
ATOM   3574  N N   . CYS A 1 475 ? 143.318 117.629 198.814 1.00 98.21  ? 475 CYS A N   1 
ATOM   3575  C CA  . CYS A 1 475 ? 142.750 117.065 197.593 1.00 98.21  ? 475 CYS A CA  1 
ATOM   3576  C C   . CYS A 1 475 ? 143.711 115.986 197.102 1.00 98.21  ? 475 CYS A C   1 
ATOM   3577  O O   . CYS A 1 475 ? 144.744 116.289 196.499 1.00 98.21  ? 475 CYS A O   1 
ATOM   3578  C CB  . CYS A 1 475 ? 142.535 118.163 196.552 1.00 98.21  ? 475 CYS A CB  1 
ATOM   3579  S SG  . CYS A 1 475 ? 141.443 117.787 195.147 1.00 98.21  ? 475 CYS A SG  1 
ATOM   3580  N N   . ASP A 1 476 ? 143.369 114.728 197.367 1.00 97.96  ? 476 ASP A N   1 
ATOM   3581  C CA  . ASP A 1 476 ? 144.223 113.604 197.018 1.00 97.96  ? 476 ASP A CA  1 
ATOM   3582  C C   . ASP A 1 476 ? 143.945 113.168 195.579 1.00 97.96  ? 476 ASP A C   1 
ATOM   3583  O O   . ASP A 1 476 ? 143.278 113.869 194.814 1.00 97.96  ? 476 ASP A O   1 
ATOM   3584  C CB  . ASP A 1 476 ? 144.028 112.462 198.012 1.00 97.96  ? 476 ASP A CB  1 
ATOM   3585  C CG  . ASP A 1 476 ? 142.677 111.800 197.877 1.00 97.96  ? 476 ASP A CG  1 
ATOM   3586  O OD1 . ASP A 1 476 ? 141.656 112.517 197.941 1.00 97.96  ? 476 ASP A OD1 1 
ATOM   3587  O OD2 . ASP A 1 476 ? 142.634 110.565 197.704 1.00 97.96  ? 476 ASP A OD2 1 
ATOM   3588  N N   . ASN A 1 477 ? 144.470 112.000 195.195 1.00 97.50  ? 477 ASN A N   1 
ATOM   3589  C CA  . ASN A 1 477 ? 144.320 111.529 193.820 1.00 97.50  ? 477 ASN A CA  1 
ATOM   3590  C C   . ASN A 1 477 ? 142.857 111.295 193.466 1.00 97.50  ? 477 ASN A C   1 
ATOM   3591  O O   . ASN A 1 477 ? 142.418 111.631 192.359 1.00 97.50  ? 477 ASN A O   1 
ATOM   3592  C CB  . ASN A 1 477 ? 145.130 110.251 193.610 1.00 97.50  ? 477 ASN A CB  1 
ATOM   3593  C CG  . ASN A 1 477 ? 146.625 110.491 193.664 1.00 97.50  ? 477 ASN A CG  1 
ATOM   3594  O OD1 . ASN A 1 477 ? 147.090 111.625 193.546 1.00 97.50  ? 477 ASN A OD1 1 
ATOM   3595  N ND2 . ASN A 1 477 ? 147.389 109.420 193.838 1.00 97.50  ? 477 ASN A ND2 1 
ATOM   3596  N N   . ALA A 1 478 ? 142.088 110.710 194.386 1.00 96.88  ? 478 ALA A N   1 
ATOM   3597  C CA  . ALA A 1 478 ? 140.662 110.525 194.139 1.00 96.88  ? 478 ALA A CA  1 
ATOM   3598  C C   . ALA A 1 478 ? 139.952 111.867 194.009 1.00 96.88  ? 478 ALA A C   1 
ATOM   3599  O O   . ALA A 1 478 ? 139.033 112.018 193.197 1.00 96.88  ? 478 ALA A O   1 
ATOM   3600  C CB  . ALA A 1 478 ? 140.038 109.687 195.255 1.00 96.88  ? 478 ALA A CB  1 
ATOM   3601  N N   . CYS A 1 479 ? 140.370 112.854 194.804 1.00 96.00  ? 479 CYS A N   1 
ATOM   3602  C CA  . CYS A 1 479 ? 139.825 114.203 194.685 1.00 96.00  ? 479 CYS A CA  1 
ATOM   3603  C C   . CYS A 1 479 ? 140.160 114.816 193.326 1.00 96.00  ? 479 CYS A C   1 
ATOM   3604  O O   . CYS A 1 479 ? 139.307 115.454 192.692 1.00 96.00  ? 479 CYS A O   1 
ATOM   3605  C CB  . CYS A 1 479 ? 140.359 115.058 195.837 1.00 96.00  ? 479 CYS A CB  1 
ATOM   3606  S SG  . CYS A 1 479 ? 139.846 116.784 195.896 1.00 96.00  ? 479 CYS A SG  1 
ATOM   3607  N N   . ILE A 1 480 ? 141.396 114.617 192.855 1.00 93.53  ? 480 ILE A N   1 
ATOM   3608  C CA  . ILE A 1 480 ? 141.784 115.082 191.523 1.00 93.53  ? 480 ILE A CA  1 
ATOM   3609  C C   . ILE A 1 480 ? 140.910 114.436 190.456 1.00 93.53  ? 480 ILE A C   1 
ATOM   3610  O O   . ILE A 1 480 ? 140.440 115.104 189.527 1.00 93.53  ? 480 ILE A O   1 
ATOM   3611  C CB  . ILE A 1 480 ? 143.276 114.795 191.264 1.00 93.53  ? 480 ILE A CB  1 
ATOM   3612  C CG1 . ILE A 1 480 ? 144.193 115.598 192.194 1.00 93.53  ? 480 ILE A CG1 1 
ATOM   3613  C CG2 . ILE A 1 480 ? 143.629 115.088 189.812 1.00 93.53  ? 480 ILE A CG2 1 
ATOM   3614  C CD1 . ILE A 1 480 ? 143.628 116.908 192.671 1.00 93.53  ? 480 ILE A CD1 1 
ATOM   3615  N N   . GLU A 1 481 ? 140.694 113.124 190.562 1.00 94.65  ? 481 GLU A N   1 
ATOM   3616  C CA  . GLU A 1 481 ? 139.887 112.426 189.568 1.00 94.65  ? 481 GLU A CA  1 
ATOM   3617  C C   . GLU A 1 481 ? 138.439 112.898 189.604 1.00 94.65  ? 481 GLU A C   1 
ATOM   3618  O O   . GLU A 1 481 ? 137.787 112.998 188.559 1.00 94.65  ? 481 GLU A O   1 
ATOM   3619  C CB  . GLU A 1 481 ? 139.973 110.918 189.792 1.00 94.65  ? 481 GLU A CB  1 
ATOM   3620  C CG  . GLU A 1 481 ? 139.270 110.091 188.732 1.00 94.65  ? 481 GLU A CG  1 
ATOM   3621  C CD  . GLU A 1 481 ? 138.831 108.736 189.248 1.00 94.65  ? 481 GLU A CD  1 
ATOM   3622  O OE1 . GLU A 1 481 ? 139.461 108.228 190.201 1.00 94.65  ? 481 GLU A OE1 1 
ATOM   3623  O OE2 . GLU A 1 481 ? 137.858 108.176 188.700 1.00 94.65  ? 481 GLU A OE2 1 
ATOM   3624  N N   . SER A 1 482 ? 137.917 113.182 190.799 1.00 93.98  ? 482 SER A N   1 
ATOM   3625  C CA  . SER A 1 482 ? 136.573 113.737 190.906 1.00 93.98  ? 482 SER A CA  1 
ATOM   3626  C C   . SER A 1 482 ? 136.486 115.093 190.221 1.00 93.98  ? 482 SER A C   1 
ATOM   3627  O O   . SER A 1 482 ? 135.493 115.396 189.550 1.00 93.98  ? 482 SER A O   1 
ATOM   3628  C CB  . SER A 1 482 ? 136.168 113.852 192.375 1.00 93.98  ? 482 SER A CB  1 
ATOM   3629  O OG  . SER A 1 482 ? 136.678 115.043 192.950 1.00 93.98  ? 482 SER A OG  1 
ATOM   3630  N N   . ILE A 1 483 ? 137.515 115.928 190.388 1.00 92.17  ? 483 ILE A N   1 
ATOM   3631  C CA  . ILE A 1 483 ? 137.536 117.218 189.699 1.00 92.17  ? 483 ILE A CA  1 
ATOM   3632  C C   . ILE A 1 483 ? 137.562 117.015 188.188 1.00 92.17  ? 483 ILE A C   1 
ATOM   3633  O O   . ILE A 1 483 ? 136.828 117.676 187.442 1.00 92.17  ? 483 ILE A O   1 
ATOM   3634  C CB  . ILE A 1 483 ? 138.732 118.062 190.175 1.00 92.17  ? 483 ILE A CB  1 
ATOM   3635  C CG1 . ILE A 1 483 ? 138.404 118.762 191.492 1.00 92.17  ? 483 ILE A CG1 1 
ATOM   3636  C CG2 . ILE A 1 483 ? 139.111 119.094 189.122 1.00 92.17  ? 483 ILE A CG2 1 
ATOM   3637  C CD1 . ILE A 1 483 ? 139.601 119.392 192.157 1.00 92.17  ? 483 ILE A CD1 1 
ATOM   3638  N N   . ARG A 1 484 ? 138.403 116.094 187.716 1.00 89.86  ? 484 ARG A N   1 
ATOM   3639  C CA  . ARG A 1 484 ? 138.557 115.886 186.278 1.00 89.86  ? 484 ARG A CA  1 
ATOM   3640  C C   . ARG A 1 484 ? 137.283 115.333 185.649 1.00 89.86  ? 484 ARG A C   1 
ATOM   3641  O O   . ARG A 1 484 ? 136.915 115.723 184.536 1.00 89.86  ? 484 ARG A O   1 
ATOM   3642  C CB  . ARG A 1 484 ? 139.737 114.953 186.010 1.00 89.86  ? 484 ARG A CB  1 
ATOM   3643  C CG  . ARG A 1 484 ? 141.094 115.602 186.212 1.00 89.86  ? 484 ARG A CG  1 
ATOM   3644  C CD  . ARG A 1 484 ? 142.152 114.933 185.358 1.00 89.86  ? 484 ARG A CD  1 
ATOM   3645  N NE  . ARG A 1 484 ? 143.289 114.485 186.151 1.00 89.86  ? 484 ARG A NE  1 
ATOM   3646  C CZ  . ARG A 1 484 ? 143.566 113.215 186.414 1.00 89.86  ? 484 ARG A CZ  1 
ATOM   3647  N NH1 . ARG A 1 484 ? 142.799 112.235 185.967 1.00 89.86  ? 484 ARG A NH1 1 
ATOM   3648  N NH2 . ARG A 1 484 ? 144.639 112.922 187.142 1.00 89.86  ? 484 ARG A NH2 1 
ATOM   3649  N N   . ASN A 1 485 ? 136.602 114.418 186.343 1.00 93.14  ? 485 ASN A N   1 
ATOM   3650  C CA  . ASN A 1 485 ? 135.399 113.808 185.787 1.00 93.14  ? 485 ASN A CA  1 
ATOM   3651  C C   . ASN A 1 485 ? 134.254 114.809 185.699 1.00 93.14  ? 485 ASN A C   1 
ATOM   3652  O O   . ASN A 1 485 ? 133.440 114.750 184.771 1.00 93.14  ? 485 ASN A O   1 
ATOM   3653  C CB  . ASN A 1 485 ? 134.982 112.602 186.628 1.00 93.14  ? 485 ASN A CB  1 
ATOM   3654  C CG  . ASN A 1 485 ? 135.807 111.367 186.328 1.00 93.14  ? 485 ASN A CG  1 
ATOM   3655  O OD1 . ASN A 1 485 ? 136.838 111.441 185.660 1.00 93.14  ? 485 ASN A OD1 1 
ATOM   3656  N ND2 . ASN A 1 485 ? 135.353 110.219 186.819 1.00 93.14  ? 485 ASN A ND2 1 
ATOM   3657  N N   . GLY A 1 486 ? 134.173 115.726 186.650 1.00 93.13  ? 486 GLY A N   1 
ATOM   3658  C CA  . GLY A 1 486 ? 133.062 116.638 186.756 1.00 93.13  ? 486 GLY A CA  1 
ATOM   3659  C C   . GLY A 1 486 ? 132.099 116.353 187.894 1.00 93.13  ? 486 GLY A C   1 
ATOM   3660  O O   . GLY A 1 486 ? 130.998 116.916 187.900 1.00 93.13  ? 486 GLY A O   1 
ATOM   3661  N N   . THR A 1 487 ? 132.476 115.500 188.849 1.00 95.44  ? 487 THR A N   1 
ATOM   3662  C CA  . THR A 1 487 ? 131.620 115.133 189.971 1.00 95.44  ? 487 THR A CA  1 
ATOM   3663  C C   . THR A 1 487 ? 132.116 115.723 191.286 1.00 95.44  ? 487 THR A C   1 
ATOM   3664  O O   . THR A 1 487 ? 131.749 115.235 192.359 1.00 95.44  ? 487 THR A O   1 
ATOM   3665  C CB  . THR A 1 487 ? 131.514 113.611 190.083 1.00 95.44  ? 487 THR A CB  1 
ATOM   3666  O OG1 . THR A 1 487 ? 130.745 113.266 191.242 1.00 95.44  ? 487 THR A OG1 1 
ATOM   3667  C CG2 . THR A 1 487 ? 132.897 112.991 190.196 1.00 95.44  ? 487 THR A CG2 1 
ATOM   3668  N N   . TYR A 1 488 ? 132.947 116.759 191.224 1.00 95.37  ? 488 TYR A N   1 
ATOM   3669  C CA  . TYR A 1 488 ? 133.504 117.355 192.431 1.00 95.37  ? 488 TYR A CA  1 
ATOM   3670  C C   . TYR A 1 488 ? 132.420 118.082 193.217 1.00 95.37  ? 488 TYR A C   1 
ATOM   3671  O O   . TYR A 1 488 ? 131.642 118.857 192.654 1.00 95.37  ? 488 TYR A O   1 
ATOM   3672  C CB  . TYR A 1 488 ? 134.636 118.312 192.060 1.00 95.37  ? 488 TYR A CB  1 
ATOM   3673  C CG  . TYR A 1 488 ? 135.145 119.172 193.196 1.00 95.37  ? 488 TYR A CG  1 
ATOM   3674  C CD1 . TYR A 1 488 ? 136.053 118.674 194.117 1.00 95.37  ? 488 TYR A CD1 1 
ATOM   3675  C CD2 . TYR A 1 488 ? 134.731 120.490 193.333 1.00 95.37  ? 488 TYR A CD2 1 
ATOM   3676  C CE1 . TYR A 1 488 ? 136.526 119.459 195.150 1.00 95.37  ? 488 TYR A CE1 1 
ATOM   3677  C CE2 . TYR A 1 488 ? 135.197 121.282 194.362 1.00 95.37  ? 488 TYR A CE2 1 
ATOM   3678  C CZ  . TYR A 1 488 ? 136.095 120.762 195.267 1.00 95.37  ? 488 TYR A CZ  1 
ATOM   3679  O OH  . TYR A 1 488 ? 136.564 121.548 196.294 1.00 95.37  ? 488 TYR A OH  1 
ATOM   3680  N N   . ASP A 1 489 ? 132.372 117.829 194.522 1.00 98.97  ? 489 ASP A N   1 
ATOM   3681  C CA  . ASP A 1 489 ? 131.399 118.438 195.424 1.00 98.97  ? 489 ASP A CA  1 
ATOM   3682  C C   . ASP A 1 489 ? 132.155 119.360 196.372 1.00 98.97  ? 489 ASP A C   1 
ATOM   3683  O O   . ASP A 1 489 ? 132.961 118.895 197.185 1.00 98.97  ? 489 ASP A O   1 
ATOM   3684  C CB  . ASP A 1 489 ? 130.625 117.367 196.187 1.00 98.97  ? 489 ASP A CB  1 
ATOM   3685  C CG  . ASP A 1 489 ? 129.511 117.944 197.039 1.00 98.97  ? 489 ASP A CG  1 
ATOM   3686  O OD1 . ASP A 1 489 ? 128.993 119.026 196.694 1.00 98.97  ? 489 ASP A OD1 1 
ATOM   3687  O OD2 . ASP A 1 489 ? 129.153 117.310 198.052 1.00 98.97  ? 489 ASP A OD2 1 
ATOM   3688  N N   . HIS A 1 490 ? 131.895 120.664 196.269 1.00 99.38  ? 490 HIS A N   1 
ATOM   3689  C CA  . HIS A 1 490 ? 132.675 121.632 197.034 1.00 99.38  ? 490 HIS A CA  1 
ATOM   3690  C C   . HIS A 1 490 ? 132.258 121.673 198.500 1.00 99.38  ? 490 HIS A C   1 
ATOM   3691  O O   . HIS A 1 490 ? 133.110 121.847 199.381 1.00 99.38  ? 490 HIS A O   1 
ATOM   3692  C CB  . HIS A 1 490 ? 132.560 123.021 196.402 1.00 99.38  ? 490 HIS A CB  1 
ATOM   3693  C CG  . HIS A 1 490 ? 131.163 123.556 196.350 1.00 99.38  ? 490 HIS A CG  1 
ATOM   3694  N ND1 . HIS A 1 490 ? 130.178 122.997 195.564 1.00 99.38  ? 490 HIS A ND1 1 
ATOM   3695  C CD2 . HIS A 1 490 ? 130.589 124.609 196.978 1.00 99.38  ? 490 HIS A CD2 1 
ATOM   3696  C CE1 . HIS A 1 490 ? 129.057 123.678 195.716 1.00 99.38  ? 490 HIS A CE1 1 
ATOM   3697  N NE2 . HIS A 1 490 ? 129.279 124.662 196.569 1.00 99.38  ? 490 HIS A NE2 1 
ATOM   3698  N N   . ASP A 1 491 ? 130.960 121.501 198.777 1.00 100.22 ? 491 ASP A N   1 
ATOM   3699  C CA  . ASP A 1 491 ? 130.461 121.583 200.149 1.00 100.22 ? 491 ASP A CA  1 
ATOM   3700  C C   . ASP A 1 491 ? 131.247 120.677 201.087 1.00 100.22 ? 491 ASP A C   1 
ATOM   3701  O O   . ASP A 1 491 ? 131.585 121.075 202.208 1.00 100.22 ? 491 ASP A O   1 
ATOM   3702  C CB  . ASP A 1 491 ? 128.977 121.222 200.189 1.00 100.22 ? 491 ASP A CB  1 
ATOM   3703  C CG  . ASP A 1 491 ? 128.089 122.352 199.718 1.00 100.22 ? 491 ASP A CG  1 
ATOM   3704  O OD1 . ASP A 1 491 ? 128.525 123.520 199.788 1.00 100.22 ? 491 ASP A OD1 1 
ATOM   3705  O OD2 . ASP A 1 491 ? 126.955 122.073 199.276 1.00 100.22 ? 491 ASP A OD2 1 
ATOM   3706  N N   . ILE A 1 492 ? 131.578 119.468 200.624 1.00 99.28  ? 492 ILE A N   1 
ATOM   3707  C CA  . ILE A 1 492 ? 132.291 118.502 201.456 1.00 99.28  ? 492 ILE A CA  1 
ATOM   3708  C C   . ILE A 1 492 ? 133.581 119.107 201.990 1.00 99.28  ? 492 ILE A C   1 
ATOM   3709  O O   . ILE A 1 492 ? 133.922 118.944 203.168 1.00 99.28  ? 492 ILE A O   1 
ATOM   3710  C CB  . ILE A 1 492 ? 132.560 117.212 200.657 1.00 99.28  ? 492 ILE A CB  1 
ATOM   3711  C CG1 . ILE A 1 492 ? 131.257 116.449 200.422 1.00 99.28  ? 492 ILE A CG1 1 
ATOM   3712  C CG2 . ILE A 1 492 ? 133.578 116.335 201.372 1.00 99.28  ? 492 ILE A CG2 1 
ATOM   3713  C CD1 . ILE A 1 492 ? 131.387 115.310 199.433 1.00 99.28  ? 492 ILE A CD1 1 
ATOM   3714  N N   . TYR A 1 493 ? 134.309 119.828 201.141 1.00 99.98  ? 493 TYR A N   1 
ATOM   3715  C CA  . TYR A 1 493 ? 135.562 120.454 201.535 1.00 99.98  ? 493 TYR A CA  1 
ATOM   3716  C C   . TYR A 1 493 ? 135.413 121.951 201.775 1.00 99.98  ? 493 TYR A C   1 
ATOM   3717  O O   . TYR A 1 493 ? 136.419 122.667 201.819 1.00 99.98  ? 493 TYR A O   1 
ATOM   3718  C CB  . TYR A 1 493 ? 136.637 120.192 200.479 1.00 99.98  ? 493 TYR A CB  1 
ATOM   3719  C CG  . TYR A 1 493 ? 136.791 118.736 200.101 1.00 99.98  ? 493 TYR A CG  1 
ATOM   3720  C CD1 . TYR A 1 493 ? 137.570 117.880 200.865 1.00 99.98  ? 493 TYR A CD1 1 
ATOM   3721  C CD2 . TYR A 1 493 ? 136.162 118.220 198.976 1.00 99.98  ? 493 TYR A CD2 1 
ATOM   3722  C CE1 . TYR A 1 493 ? 137.716 116.551 200.524 1.00 99.98  ? 493 TYR A CE1 1 
ATOM   3723  C CE2 . TYR A 1 493 ? 136.301 116.892 198.627 1.00 99.98  ? 493 TYR A CE2 1 
ATOM   3724  C CZ  . TYR A 1 493 ? 137.080 116.062 199.404 1.00 99.98  ? 493 TYR A CZ  1 
ATOM   3725  O OH  . TYR A 1 493 ? 137.224 114.738 199.061 1.00 99.98  ? 493 TYR A OH  1 
ATOM   3726  N N   . ARG A 1 494 ? 134.180 122.438 201.930 1.00 100.61 ? 494 ARG A N   1 
ATOM   3727  C CA  . ARG A 1 494 ? 133.960 123.880 201.984 1.00 100.61 ? 494 ARG A CA  1 
ATOM   3728  C C   . ARG A 1 494 ? 134.573 124.492 203.240 1.00 100.61 ? 494 ARG A C   1 
ATOM   3729  O O   . ARG A 1 494 ? 135.522 125.283 203.160 1.00 100.61 ? 494 ARG A O   1 
ATOM   3730  C CB  . ARG A 1 494 ? 132.462 124.178 201.912 1.00 100.61 ? 494 ARG A CB  1 
ATOM   3731  C CG  . ARG A 1 494 ? 132.127 125.645 201.705 1.00 100.61 ? 494 ARG A CG  1 
ATOM   3732  C CD  . ARG A 1 494 ? 130.628 125.856 201.584 1.00 100.61 ? 494 ARG A CD  1 
ATOM   3733  N NE  . ARG A 1 494 ? 130.295 127.244 201.289 1.00 100.61 ? 494 ARG A NE  1 
ATOM   3734  C CZ  . ARG A 1 494 ? 130.336 127.782 200.078 1.00 100.61 ? 494 ARG A CZ  1 
ATOM   3735  N NH1 . ARG A 1 494 ? 130.681 127.071 199.017 1.00 100.61 ? 494 ARG A NH1 1 
ATOM   3736  N NH2 . ARG A 1 494 ? 130.027 129.067 199.928 1.00 100.61 ? 494 ARG A NH2 1 
ATOM   3737  N N   . ASP A 1 495 ? 134.066 124.100 204.414 1.00 102.36 ? 495 ASP A N   1 
ATOM   3738  C CA  . ASP A 1 495 ? 134.430 124.778 205.657 1.00 102.36 ? 495 ASP A CA  1 
ATOM   3739  C C   . ASP A 1 495 ? 135.938 124.790 205.860 1.00 102.36 ? 495 ASP A C   1 
ATOM   3740  O O   . ASP A 1 495 ? 136.532 125.842 206.129 1.00 102.36 ? 495 ASP A O   1 
ATOM   3741  C CB  . ASP A 1 495 ? 133.737 124.107 206.843 1.00 102.36 ? 495 ASP A CB  1 
ATOM   3742  C CG  . ASP A 1 495 ? 132.280 123.799 206.568 1.00 102.36 ? 495 ASP A CG  1 
ATOM   3743  O OD1 . ASP A 1 495 ? 131.516 124.741 206.267 1.00 102.36 ? 495 ASP A OD1 1 
ATOM   3744  O OD2 . ASP A 1 495 ? 131.899 122.612 206.653 1.00 102.36 ? 495 ASP A OD2 1 
ATOM   3745  N N   . GLU A 1 496 ? 136.578 123.629 205.700 1.00 101.27 ? 496 GLU A N   1 
ATOM   3746  C CA  . GLU A 1 496 ? 138.022 123.537 205.880 1.00 101.27 ? 496 GLU A CA  1 
ATOM   3747  C C   . GLU A 1 496 ? 138.746 124.551 205.007 1.00 101.27 ? 496 GLU A C   1 
ATOM   3748  O O   . GLU A 1 496 ? 139.636 125.271 205.477 1.00 101.27 ? 496 GLU A O   1 
ATOM   3749  C CB  . GLU A 1 496 ? 138.497 122.117 205.567 1.00 101.27 ? 496 GLU A CB  1 
ATOM   3750  C CG  . GLU A 1 496 ? 139.966 122.028 205.197 1.00 101.27 ? 496 GLU A CG  1 
ATOM   3751  C CD  . GLU A 1 496 ? 140.366 120.647 204.716 1.00 101.27 ? 496 GLU A CD  1 
ATOM   3752  O OE1 . GLU A 1 496 ? 139.473 119.789 204.557 1.00 101.27 ? 496 GLU A OE1 1 
ATOM   3753  O OE2 . GLU A 1 496 ? 141.574 120.420 204.496 1.00 101.27 ? 496 GLU A OE2 1 
ATOM   3754  N N   . ALA A 1 497 ? 138.347 124.650 203.735 1.00 101.35 ? 497 ALA A N   1 
ATOM   3755  C CA  . ALA A 1 497 ? 138.999 125.600 202.841 1.00 101.35 ? 497 ALA A CA  1 
ATOM   3756  C C   . ALA A 1 497 ? 138.848 127.022 203.360 1.00 101.35 ? 497 ALA A C   1 
ATOM   3757  O O   . ALA A 1 497 ? 139.810 127.800 203.350 1.00 101.35 ? 497 ALA A O   1 
ATOM   3758  C CB  . ALA A 1 497 ? 138.427 125.475 201.430 1.00 101.35 ? 497 ALA A CB  1 
ATOM   3759  N N   . LEU A 1 498 ? 137.657 127.364 203.861 1.00 101.70 ? 498 LEU A N   1 
ATOM   3760  C CA  . LEU A 1 498 ? 137.441 128.707 204.384 1.00 101.70 ? 498 LEU A CA  1 
ATOM   3761  C C   . LEU A 1 498 ? 138.353 128.997 205.567 1.00 101.70 ? 498 LEU A C   1 
ATOM   3762  O O   . LEU A 1 498 ? 138.687 130.159 205.822 1.00 101.70 ? 498 LEU A O   1 
ATOM   3763  C CB  . LEU A 1 498 ? 135.975 128.889 204.778 1.00 101.70 ? 498 LEU A CB  1 
ATOM   3764  C CG  . LEU A 1 498 ? 135.049 129.344 203.650 1.00 101.70 ? 498 LEU A CG  1 
ATOM   3765  C CD1 . LEU A 1 498 ? 133.730 129.865 204.198 1.00 101.70 ? 498 LEU A CD1 1 
ATOM   3766  C CD2 . LEU A 1 498 ? 135.734 130.402 202.799 1.00 101.70 ? 498 LEU A CD2 1 
ATOM   3767  N N   . ASN A 1 499 ? 138.770 127.961 206.296 1.00 102.51 ? 499 ASN A N   1 
ATOM   3768  C CA  . ASN A 1 499 ? 139.730 128.173 207.371 1.00 102.51 ? 499 ASN A CA  1 
ATOM   3769  C C   . ASN A 1 499 ? 141.140 128.361 206.826 1.00 102.51 ? 499 ASN A C   1 
ATOM   3770  O O   . ASN A 1 499 ? 141.912 129.166 207.360 1.00 102.51 ? 499 ASN A O   1 
ATOM   3771  C CB  . ASN A 1 499 ? 139.684 127.003 208.353 1.00 102.51 ? 499 ASN A CB  1 
ATOM   3772  C CG  . ASN A 1 499 ? 138.368 126.924 209.100 1.00 102.51 ? 499 ASN A CG  1 
ATOM   3773  O OD1 . ASN A 1 499 ? 137.672 127.926 209.261 1.00 102.51 ? 499 ASN A OD1 1 
ATOM   3774  N ND2 . ASN A 1 499 ? 138.018 125.728 209.558 1.00 102.51 ? 499 ASN A ND2 1 
ATOM   3775  N N   . ASN A 1 500 ? 141.490 127.633 205.763 1.00 101.17 ? 500 ASN A N   1 
ATOM   3776  C CA  . ASN A 1 500 ? 142.858 127.689 205.257 1.00 101.17 ? 500 ASN A CA  1 
ATOM   3777  C C   . ASN A 1 500 ? 143.125 128.991 204.515 1.00 101.17 ? 500 ASN A C   1 
ATOM   3778  O O   . ASN A 1 500 ? 144.208 129.573 204.640 1.00 101.17 ? 500 ASN A O   1 
ATOM   3779  C CB  . ASN A 1 500 ? 143.132 126.489 204.352 1.00 101.17 ? 500 ASN A CB  1 
ATOM   3780  C CG  . ASN A 1 500 ? 144.052 125.472 204.998 1.00 101.17 ? 500 ASN A CG  1 
ATOM   3781  O OD1 . ASN A 1 500 ? 144.902 125.819 205.817 1.00 101.17 ? 500 ASN A OD1 1 
ATOM   3782  N ND2 . ASN A 1 500 ? 143.886 124.207 204.631 1.00 101.17 ? 500 ASN A ND2 1 
ATOM   3783  N N   . ARG A 1 501 ? 142.150 129.464 203.738 1.00 101.56 ? 501 ARG A N   1 
ATOM   3784  C CA  . ARG A 1 501 ? 142.364 130.642 202.909 1.00 101.56 ? 501 ARG A CA  1 
ATOM   3785  C C   . ARG A 1 501 ? 142.340 131.932 203.719 1.00 101.56 ? 501 ARG A C   1 
ATOM   3786  O O   . ARG A 1 501 ? 143.112 132.853 203.429 1.00 101.56 ? 501 ARG A O   1 
ATOM   3787  C CB  . ARG A 1 501 ? 141.311 130.692 201.801 1.00 101.56 ? 501 ARG A CB  1 
ATOM   3788  C CG  . ARG A 1 501 ? 141.595 131.708 200.712 1.00 101.56 ? 501 ARG A CG  1 
ATOM   3789  C CD  . ARG A 1 501 ? 141.080 131.221 199.366 1.00 101.56 ? 501 ARG A CD  1 
ATOM   3790  N NE  . ARG A 1 501 ? 139.631 131.066 199.353 1.00 101.56 ? 501 ARG A NE  1 
ATOM   3791  C CZ  . ARG A 1 501 ? 138.802 131.843 198.670 1.00 101.56 ? 501 ARG A CZ  1 
ATOM   3792  N NH1 . ARG A 1 501 ? 139.246 132.848 197.933 1.00 101.56 ? 501 ARG A NH1 1 
ATOM   3793  N NH2 . ARG A 1 501 ? 137.495 131.607 198.728 1.00 101.56 ? 501 ARG A NH2 1 
ATOM   3794  N N   . PHE A 1 502 ? 141.479 132.019 204.727 1.00 103.39 ? 502 PHE A N   1 
ATOM   3795  C CA  . PHE A 1 502 ? 141.355 133.239 205.515 1.00 103.39 ? 502 PHE A CA  1 
ATOM   3796  C C   . PHE A 1 502 ? 141.916 133.048 206.920 1.00 103.39 ? 502 PHE A C   1 
ATOM   3797  O O   . PHE A 1 502 ? 142.454 133.983 207.514 1.00 103.39 ? 502 PHE A O   1 
ATOM   3798  C CB  . PHE A 1 502 ? 139.893 133.682 205.584 1.00 103.39 ? 502 PHE A CB  1 
ATOM   3799  C CG  . PHE A 1 502 ? 139.312 134.059 204.252 1.00 103.39 ? 502 PHE A CG  1 
ATOM   3800  C CD1 . PHE A 1 502 ? 140.093 134.677 203.290 1.00 103.39 ? 502 PHE A CD1 1 
ATOM   3801  C CD2 . PHE A 1 502 ? 137.986 133.791 203.959 1.00 103.39 ? 502 PHE A CD2 1 
ATOM   3802  C CE1 . PHE A 1 502 ? 139.562 135.025 202.062 1.00 103.39 ? 502 PHE A CE1 1 
ATOM   3803  C CE2 . PHE A 1 502 ? 137.448 134.135 202.732 1.00 103.39 ? 502 PHE A CE2 1 
ATOM   3804  C CZ  . PHE A 1 502 ? 138.238 134.753 201.783 1.00 103.39 ? 502 PHE A CZ  1 
ATOM   3805  N N   . THR B 1 12  ? 142.739 152.916 201.104 1.00 95.12  ? 12  THR B N   1 
ATOM   3806  C CA  . THR B 1 12  ? 142.347 152.389 199.802 1.00 95.12  ? 12  THR B CA  1 
ATOM   3807  C C   . THR B 1 12  ? 142.921 153.232 198.667 1.00 95.12  ? 12  THR B C   1 
ATOM   3808  O O   . THR B 1 12  ? 143.328 154.373 198.874 1.00 95.12  ? 12  THR B O   1 
ATOM   3809  C CB  . THR B 1 12  ? 140.815 152.329 199.654 1.00 95.12  ? 12  THR B CB  1 
ATOM   3810  O OG1 . THR B 1 12  ? 140.270 153.651 199.750 1.00 95.12  ? 12  THR B OG1 1 
ATOM   3811  C CG2 . THR B 1 12  ? 140.205 151.452 200.737 1.00 95.12  ? 12  THR B CG2 1 
ATOM   3812  N N   . ALA B 1 13  ? 142.950 152.657 197.467 1.00 92.56  ? 13  ALA B N   1 
ATOM   3813  C CA  . ALA B 1 13  ? 143.420 153.345 196.273 1.00 92.56  ? 13  ALA B CA  1 
ATOM   3814  C C   . ALA B 1 13  ? 142.573 152.894 195.093 1.00 92.56  ? 13  ALA B C   1 
ATOM   3815  O O   . ALA B 1 13  ? 141.852 151.899 195.171 1.00 92.56  ? 13  ALA B O   1 
ATOM   3816  C CB  . ALA B 1 13  ? 144.907 153.075 196.016 1.00 92.56  ? 13  ALA B CB  1 
ATOM   3817  N N   . THR B 1 14  ? 142.650 153.633 193.989 1.00 88.13  ? 14  THR B N   1 
ATOM   3818  C CA  . THR B 1 14  ? 141.893 153.288 192.793 1.00 88.13  ? 14  THR B CA  1 
ATOM   3819  C C   . THR B 1 14  ? 142.840 153.110 191.617 1.00 88.13  ? 14  THR B C   1 
ATOM   3820  O O   . THR B 1 14  ? 143.768 153.902 191.437 1.00 88.13  ? 14  THR B O   1 
ATOM   3821  C CB  . THR B 1 14  ? 140.848 154.361 192.464 1.00 88.13  ? 14  THR B CB  1 
ATOM   3822  O OG1 . THR B 1 14  ? 140.161 154.744 193.662 1.00 88.13  ? 14  THR B OG1 1 
ATOM   3823  C CG2 . THR B 1 14  ? 139.839 153.836 191.453 1.00 88.13  ? 14  THR B CG2 1 
ATOM   3824  N N   . LEU B 1 15  ? 142.600 152.072 190.816 1.00 83.44  ? 15  LEU B N   1 
ATOM   3825  C CA  . LEU B 1 15  ? 143.389 151.800 189.619 1.00 83.44  ? 15  LEU B CA  1 
ATOM   3826  C C   . LEU B 1 15  ? 142.437 151.509 188.468 1.00 83.44  ? 15  LEU B C   1 
ATOM   3827  O O   . LEU B 1 15  ? 141.698 150.523 188.505 1.00 83.44  ? 15  LEU B O   1 
ATOM   3828  C CB  . LEU B 1 15  ? 144.345 150.628 189.840 1.00 83.44  ? 15  LEU B CB  1 
ATOM   3829  C CG  . LEU B 1 15  ? 145.330 150.374 188.700 1.00 83.44  ? 15  LEU B CG  1 
ATOM   3830  C CD1 . LEU B 1 15  ? 146.296 151.538 188.567 1.00 83.44  ? 15  LEU B CD1 1 
ATOM   3831  C CD2 . LEU B 1 15  ? 146.074 149.071 188.914 1.00 83.44  ? 15  LEU B CD2 1 
ATOM   3832  N N   . CYS B 1 16  ? 142.462 152.349 187.442 1.00 79.81  ? 16  CYS B N   1 
ATOM   3833  C CA  . CYS B 1 16  ? 141.579 152.214 186.296 1.00 79.81  ? 16  CYS B CA  1 
ATOM   3834  C C   . CYS B 1 16  ? 142.385 151.966 185.029 1.00 79.81  ? 16  CYS B C   1 
ATOM   3835  O O   . CYS B 1 16  ? 143.534 152.398 184.907 1.00 79.81  ? 16  CYS B O   1 
ATOM   3836  C CB  . CYS B 1 16  ? 140.713 153.463 186.127 1.00 79.81  ? 16  CYS B CB  1 
ATOM   3837  S SG  . CYS B 1 16  ? 139.592 153.748 187.504 1.00 79.81  ? 16  CYS B SG  1 
ATOM   3838  N N   . LEU B 1 17  ? 141.769 151.261 184.085 1.00 74.56  ? 17  LEU B N   1 
ATOM   3839  C CA  . LEU B 1 17  ? 142.373 150.961 182.796 1.00 74.56  ? 17  LEU B CA  1 
ATOM   3840  C C   . LEU B 1 17  ? 141.550 151.612 181.695 1.00 74.56  ? 17  LEU B C   1 
ATOM   3841  O O   . LEU B 1 17  ? 140.317 151.621 181.758 1.00 74.56  ? 17  LEU B O   1 
ATOM   3842  C CB  . LEU B 1 17  ? 142.465 149.451 182.571 1.00 74.56  ? 17  LEU B CB  1 
ATOM   3843  C CG  . LEU B 1 17  ? 143.458 148.719 183.475 1.00 74.56  ? 17  LEU B CG  1 
ATOM   3844  C CD1 . LEU B 1 17  ? 142.745 148.041 184.634 1.00 74.56  ? 17  LEU B CD1 1 
ATOM   3845  C CD2 . LEU B 1 17  ? 144.261 147.712 182.681 1.00 74.56  ? 17  LEU B CD2 1 
ATOM   3846  N N   . GLY B 1 18  ? 142.227 152.162 180.690 1.00 70.00  ? 18  GLY B N   1 
ATOM   3847  C CA  . GLY B 1 18  ? 141.503 152.878 179.658 1.00 70.00  ? 18  GLY B CA  1 
ATOM   3848  C C   . GLY B 1 18  ? 142.250 152.907 178.344 1.00 70.00  ? 18  GLY B C   1 
ATOM   3849  O O   . GLY B 1 18  ? 143.392 152.454 178.237 1.00 70.00  ? 18  GLY B O   1 
ATOM   3850  N N   . HIS B 1 19  ? 141.579 153.460 177.336 1.00 66.34  ? 19  HIS B N   1 
ATOM   3851  C CA  . HIS B 1 19  ? 142.116 153.558 175.988 1.00 66.34  ? 19  HIS B CA  1 
ATOM   3852  C C   . HIS B 1 19  ? 141.878 154.960 175.441 1.00 66.34  ? 19  HIS B C   1 
ATOM   3853  O O   . HIS B 1 19  ? 140.953 155.663 175.853 1.00 66.34  ? 19  HIS B O   1 
ATOM   3854  C CB  . HIS B 1 19  ? 141.493 152.509 175.053 1.00 66.34  ? 19  HIS B CB  1 
ATOM   3855  C CG  . HIS B 1 19  ? 140.022 152.682 174.841 1.00 66.34  ? 19  HIS B CG  1 
ATOM   3856  N ND1 . HIS B 1 19  ? 139.084 151.882 175.455 1.00 66.34  ? 19  HIS B ND1 1 
ATOM   3857  C CD2 . HIS B 1 19  ? 139.327 153.561 174.082 1.00 66.34  ? 19  HIS B CD2 1 
ATOM   3858  C CE1 . HIS B 1 19  ? 137.874 152.263 175.086 1.00 66.34  ? 19  HIS B CE1 1 
ATOM   3859  N NE2 . HIS B 1 19  ? 137.993 153.280 174.253 1.00 66.34  ? 19  HIS B NE2 1 
ATOM   3860  N N   . HIS B 1 20  ? 142.726 155.353 174.495 1.00 66.19  ? 20  HIS B N   1 
ATOM   3861  C CA  . HIS B 1 20  ? 142.717 156.711 173.974 1.00 66.19  ? 20  HIS B CA  1 
ATOM   3862  C C   . HIS B 1 20  ? 141.529 156.945 173.042 1.00 66.19  ? 20  HIS B C   1 
ATOM   3863  O O   . HIS B 1 20  ? 140.885 156.010 172.558 1.00 66.19  ? 20  HIS B O   1 
ATOM   3864  C CB  . HIS B 1 20  ? 144.023 157.003 173.235 1.00 66.19  ? 20  HIS B CB  1 
ATOM   3865  C CG  . HIS B 1 20  ? 144.074 156.437 171.851 1.00 66.19  ? 20  HIS B CG  1 
ATOM   3866  N ND1 . HIS B 1 20  ? 144.583 157.137 170.779 1.00 66.19  ? 20  HIS B ND1 1 
ATOM   3867  C CD2 . HIS B 1 20  ? 143.679 155.238 171.362 1.00 66.19  ? 20  HIS B CD2 1 
ATOM   3868  C CE1 . HIS B 1 20  ? 144.500 156.394 169.690 1.00 66.19  ? 20  HIS B CE1 1 
ATOM   3869  N NE2 . HIS B 1 20  ? 143.954 155.237 170.016 1.00 66.19  ? 20  HIS B NE2 1 
ATOM   3870  N N   . SER B 1 21  ? 141.251 158.222 172.791 1.00 65.82  ? 21  SER B N   1 
ATOM   3871  C CA  . SER B 1 21  ? 140.196 158.630 171.873 1.00 65.82  ? 21  SER B CA  1 
ATOM   3872  C C   . SER B 1 21  ? 140.591 159.952 171.229 1.00 65.82  ? 21  SER B C   1 
ATOM   3873  O O   . SER B 1 21  ? 141.495 160.646 171.700 1.00 65.82  ? 21  SER B O   1 
ATOM   3874  C CB  . SER B 1 21  ? 138.845 158.752 172.585 1.00 65.82  ? 21  SER B CB  1 
ATOM   3875  O OG  . SER B 1 21  ? 138.554 160.101 172.897 1.00 65.82  ? 21  SER B OG  1 
ATOM   3876  N N   . VAL B 1 22  ? 139.904 160.295 170.142 1.00 62.27  ? 22  VAL B N   1 
ATOM   3877  C CA  . VAL B 1 22  ? 140.227 161.498 169.374 1.00 62.27  ? 22  VAL B CA  1 
ATOM   3878  C C   . VAL B 1 22  ? 138.979 162.360 169.225 1.00 62.27  ? 22  VAL B C   1 
ATOM   3879  O O   . VAL B 1 22  ? 137.857 161.835 169.250 1.00 62.27  ? 22  VAL B O   1 
ATOM   3880  C CB  . VAL B 1 22  ? 140.819 161.139 168.001 1.00 62.27  ? 22  VAL B CB  1 
ATOM   3881  C CG1 . VAL B 1 22  ? 142.177 160.475 168.166 1.00 62.27  ? 22  VAL B CG1 1 
ATOM   3882  C CG2 . VAL B 1 22  ? 139.869 160.243 167.227 1.00 62.27  ? 22  VAL B CG2 1 
ATOM   3883  N N   . PRO B 1 23  ? 139.119 163.683 169.081 1.00 64.05  ? 23  PRO B N   1 
ATOM   3884  C CA  . PRO B 1 23  ? 137.922 164.532 168.980 1.00 64.05  ? 23  PRO B CA  1 
ATOM   3885  C C   . PRO B 1 23  ? 137.151 164.358 167.682 1.00 64.05  ? 23  PRO B C   1 
ATOM   3886  O O   . PRO B 1 23  ? 135.932 164.565 167.675 1.00 64.05  ? 23  PRO B O   1 
ATOM   3887  C CB  . PRO B 1 23  ? 138.484 165.955 169.114 1.00 64.05  ? 23  PRO B CB  1 
ATOM   3888  C CG  . PRO B 1 23  ? 139.919 165.841 168.736 1.00 64.05  ? 23  PRO B CG  1 
ATOM   3889  C CD  . PRO B 1 23  ? 140.360 164.473 169.150 1.00 64.05  ? 23  PRO B CD  1 
ATOM   3890  N N   . ASN B 1 24  ? 137.813 163.991 166.587 1.00 62.40  ? 24  ASN B N   1 
ATOM   3891  C CA  . ASN B 1 24  ? 137.156 163.818 165.294 1.00 62.40  ? 24  ASN B CA  1 
ATOM   3892  C C   . ASN B 1 24  ? 137.520 162.457 164.711 1.00 62.40  ? 24  ASN B C   1 
ATOM   3893  O O   . ASN B 1 24  ? 138.651 162.248 164.262 1.00 62.40  ? 24  ASN B O   1 
ATOM   3894  C CB  . ASN B 1 24  ? 137.526 164.955 164.337 1.00 62.40  ? 24  ASN B CB  1 
ATOM   3895  C CG  . ASN B 1 24  ? 139.026 165.155 164.210 1.00 62.40  ? 24  ASN B CG  1 
ATOM   3896  O OD1 . ASN B 1 24  ? 139.810 164.599 164.980 1.00 62.40  ? 24  ASN B OD1 1 
ATOM   3897  N ND2 . ASN B 1 24  ? 139.431 165.956 163.233 1.00 62.40  ? 24  ASN B ND2 1 
ATOM   3898  N N   . GLY B 1 25  ? 136.558 161.534 164.715 1.00 55.93  ? 25  GLY B N   1 
ATOM   3899  C CA  . GLY B 1 25  ? 136.737 160.210 164.166 1.00 55.93  ? 25  GLY B CA  1 
ATOM   3900  C C   . GLY B 1 25  ? 136.174 160.082 162.758 1.00 55.93  ? 25  GLY B C   1 
ATOM   3901  O O   . GLY B 1 25  ? 135.631 161.018 162.179 1.00 55.93  ? 25  GLY B O   1 
ATOM   3902  N N   . THR B 1 26  ? 136.315 158.874 162.213 1.00 51.05  ? 26  THR B N   1 
ATOM   3903  C CA  . THR B 1 26  ? 135.899 158.583 160.847 1.00 51.05  ? 26  THR B CA  1 
ATOM   3904  C C   . THR B 1 26  ? 135.028 157.335 160.814 1.00 51.05  ? 26  THR B C   1 
ATOM   3905  O O   . THR B 1 26  ? 135.241 156.389 161.573 1.00 51.05  ? 26  THR B O   1 
ATOM   3906  C CB  . THR B 1 26  ? 137.114 158.407 159.925 1.00 51.05  ? 26  THR B CB  1 
ATOM   3907  O OG1 . THR B 1 26  ? 136.705 157.794 158.696 1.00 51.05  ? 26  THR B OG1 1 
ATOM   3908  C CG2 . THR B 1 26  ? 138.172 157.556 160.597 1.00 51.05  ? 26  THR B CG2 1 
ATOM   3909  N N   . ILE B 1 27  ? 134.050 157.337 159.914 1.00 48.39  ? 27  ILE B N   1 
ATOM   3910  C CA  . ILE B 1 27  ? 133.051 156.276 159.831 1.00 48.39  ? 27  ILE B CA  1 
ATOM   3911  C C   . ILE B 1 27  ? 133.517 155.218 158.840 1.00 48.39  ? 27  ILE B C   1 
ATOM   3912  O O   . ILE B 1 27  ? 133.983 155.545 157.742 1.00 48.39  ? 27  ILE B O   1 
ATOM   3913  C CB  . ILE B 1 27  ? 131.682 156.844 159.421 1.00 48.39  ? 27  ILE B CB  1 
ATOM   3914  C CG1 . ILE B 1 27  ? 131.307 158.034 160.305 1.00 48.39  ? 27  ILE B CG1 1 
ATOM   3915  C CG2 . ILE B 1 27  ? 130.613 155.766 159.480 1.00 48.39  ? 27  ILE B CG2 1 
ATOM   3916  C CD1 . ILE B 1 27  ? 130.900 157.650 161.707 1.00 48.39  ? 27  ILE B CD1 1 
ATOM   3917  N N   . VAL B 1 28  ? 133.400 153.946 159.228 1.00 45.13  ? 28  VAL B N   1 
ATOM   3918  C CA  . VAL B 1 28  ? 133.687 152.814 158.357 1.00 45.13  ? 28  VAL B CA  1 
ATOM   3919  C C   . VAL B 1 28  ? 132.561 151.797 158.496 1.00 45.13  ? 28  VAL B C   1 
ATOM   3920  O O   . VAL B 1 28  ? 131.687 151.914 159.356 1.00 45.13  ? 28  VAL B O   1 
ATOM   3921  C CB  . VAL B 1 28  ? 135.050 152.153 158.661 1.00 45.13  ? 28  VAL B CB  1 
ATOM   3922  C CG1 . VAL B 1 28  ? 136.189 153.126 158.416 1.00 45.13  ? 28  VAL B CG1 1 
ATOM   3923  C CG2 . VAL B 1 28  ? 135.084 151.628 160.083 1.00 45.13  ? 28  VAL B CG2 1 
ATOM   3924  N N   . LYS B 1 29  ? 132.600 150.784 157.634 1.00 44.09  ? 29  LYS B N   1 
ATOM   3925  C CA  . LYS B 1 29  ? 131.597 149.729 157.594 1.00 44.09  ? 29  LYS B CA  1 
ATOM   3926  C C   . LYS B 1 29  ? 132.257 148.374 157.810 1.00 44.09  ? 29  LYS B C   1 
ATOM   3927  O O   . LYS B 1 29  ? 133.323 148.098 157.253 1.00 44.09  ? 29  LYS B O   1 
ATOM   3928  C CB  . LYS B 1 29  ? 130.847 149.741 156.257 1.00 44.09  ? 29  LYS B CB  1 
ATOM   3929  C CG  . LYS B 1 29  ? 129.994 148.512 156.005 1.00 44.09  ? 29  LYS B CG  1 
ATOM   3930  C CD  . LYS B 1 29  ? 130.052 148.089 154.548 1.00 44.09  ? 29  LYS B CD  1 
ATOM   3931  C CE  . LYS B 1 29  ? 128.949 148.750 153.743 1.00 44.09  ? 29  LYS B CE  1 
ATOM   3932  N NZ  . LYS B 1 29  ? 129.352 148.948 152.326 1.00 44.09  ? 29  LYS B NZ  1 
ATOM   3933  N N   . THR B 1 30  ? 131.622 147.533 158.620 1.00 43.52  ? 30  THR B N   1 
ATOM   3934  C CA  . THR B 1 30  ? 132.093 146.183 158.903 1.00 43.52  ? 30  THR B CA  1 
ATOM   3935  C C   . THR B 1 30  ? 131.055 145.162 158.440 1.00 43.52  ? 30  THR B C   1 
ATOM   3936  O O   . THR B 1 30  ? 130.011 145.508 157.886 1.00 43.52  ? 30  THR B O   1 
ATOM   3937  C CB  . THR B 1 30  ? 132.396 146.004 160.396 1.00 43.52  ? 30  THR B CB  1 
ATOM   3938  O OG1 . THR B 1 30  ? 131.185 146.119 161.152 1.00 43.52  ? 30  THR B OG1 1 
ATOM   3939  C CG2 . THR B 1 30  ? 133.390 147.048 160.877 1.00 43.52  ? 30  THR B CG2 1 
ATOM   3940  N N   . ILE B 1 31  ? 131.361 143.885 158.677 1.00 43.39  ? 31  ILE B N   1 
ATOM   3941  C CA  . ILE B 1 31  ? 130.433 142.809 158.337 1.00 43.39  ? 31  ILE B CA  1 
ATOM   3942  C C   . ILE B 1 31  ? 129.164 142.916 159.172 1.00 43.39  ? 31  ILE B C   1 
ATOM   3943  O O   . ILE B 1 31  ? 128.057 142.648 158.690 1.00 43.39  ? 31  ILE B O   1 
ATOM   3944  C CB  . ILE B 1 31  ? 131.121 141.442 158.523 1.00 43.39  ? 31  ILE B CB  1 
ATOM   3945  C CG1 . ILE B 1 31  ? 131.996 141.110 157.314 1.00 43.39  ? 31  ILE B CG1 1 
ATOM   3946  C CG2 . ILE B 1 31  ? 130.100 140.335 158.774 1.00 43.39  ? 31  ILE B CG2 1 
ATOM   3947  C CD1 . ILE B 1 31  ? 131.237 141.051 156.017 1.00 43.39  ? 31  ILE B CD1 1 
ATOM   3948  N N   . THR B 1 32  ? 129.300 143.337 160.426 1.00 48.15  ? 32  THR B N   1 
ATOM   3949  C CA  . THR B 1 32  ? 128.206 143.313 161.384 1.00 48.15  ? 32  THR B CA  1 
ATOM   3950  C C   . THR B 1 32  ? 127.505 144.658 161.550 1.00 48.15  ? 32  THR B C   1 
ATOM   3951  O O   . THR B 1 32  ? 126.291 144.683 161.775 1.00 48.15  ? 32  THR B O   1 
ATOM   3952  C CB  . THR B 1 32  ? 128.737 142.813 162.737 1.00 48.15  ? 32  THR B CB  1 
ATOM   3953  O OG1 . THR B 1 32  ? 128.792 141.380 162.725 1.00 48.15  ? 32  THR B OG1 1 
ATOM   3954  C CG2 . THR B 1 32  ? 127.870 143.261 163.887 1.00 48.15  ? 32  THR B CG2 1 
ATOM   3955  N N   . ASP B 1 33  ? 128.214 145.775 161.399 1.00 50.58  ? 33  ASP B N   1 
ATOM   3956  C CA  . ASP B 1 33  ? 127.644 147.101 161.601 1.00 50.58  ? 33  ASP B CA  1 
ATOM   3957  C C   . ASP B 1 33  ? 127.668 147.901 160.306 1.00 50.58  ? 33  ASP B C   1 
ATOM   3958  O O   . ASP B 1 33  ? 128.641 147.848 159.549 1.00 50.58  ? 33  ASP B O   1 
ATOM   3959  C CB  . ASP B 1 33  ? 128.401 147.874 162.687 1.00 50.58  ? 33  ASP B CB  1 
ATOM   3960  C CG  . ASP B 1 33  ? 128.350 147.189 164.036 1.00 50.58  ? 33  ASP B CG  1 
ATOM   3961  O OD1 . ASP B 1 33  ? 127.447 146.354 164.248 1.00 50.58  ? 33  ASP B OD1 1 
ATOM   3962  O OD2 . ASP B 1 33  ? 129.201 147.500 164.894 1.00 50.58  ? 33  ASP B OD2 1 
ATOM   3963  N N   . ASP B 1 34  ? 126.590 148.651 160.064 1.00 52.88  ? 34  ASP B N   1 
ATOM   3964  C CA  . ASP B 1 34  ? 126.538 149.525 158.895 1.00 52.88  ? 34  ASP B CA  1 
ATOM   3965  C C   . ASP B 1 34  ? 127.497 150.703 159.037 1.00 52.88  ? 34  ASP B C   1 
ATOM   3966  O O   . ASP B 1 34  ? 128.155 151.094 158.067 1.00 52.88  ? 34  ASP B O   1 
ATOM   3967  C CB  . ASP B 1 34  ? 125.111 150.026 158.676 1.00 52.88  ? 34  ASP B CB  1 
ATOM   3968  C CG  . ASP B 1 34  ? 124.140 148.908 158.348 1.00 52.88  ? 34  ASP B CG  1 
ATOM   3969  O OD1 . ASP B 1 34  ? 124.368 148.187 157.355 1.00 52.88  ? 34  ASP B OD1 1 
ATOM   3970  O OD2 . ASP B 1 34  ? 123.143 148.752 159.082 1.00 52.88  ? 34  ASP B OD2 1 
ATOM   3971  N N   . GLN B 1 35  ? 127.579 151.288 160.231 1.00 52.57  ? 35  GLN B N   1 
ATOM   3972  C CA  . GLN B 1 35  ? 128.438 152.438 160.483 1.00 52.57  ? 35  GLN B CA  1 
ATOM   3973  C C   . GLN B 1 35  ? 129.062 152.316 161.863 1.00 52.57  ? 35  GLN B C   1 
ATOM   3974  O O   . GLN B 1 35  ? 128.349 152.150 162.855 1.00 52.57  ? 35  GLN B O   1 
ATOM   3975  C CB  . GLN B 1 35  ? 127.659 153.756 160.388 1.00 52.57  ? 35  GLN B CB  1 
ATOM   3976  C CG  . GLN B 1 35  ? 126.961 154.000 159.064 1.00 52.57  ? 35  GLN B CG  1 
ATOM   3977  C CD  . GLN B 1 35  ? 126.650 155.465 158.838 1.00 52.57  ? 35  GLN B CD  1 
ATOM   3978  O OE1 . GLN B 1 35  ? 126.424 156.216 159.786 1.00 52.57  ? 35  GLN B OE1 1 
ATOM   3979  N NE2 . GLN B 1 35  ? 126.647 155.883 157.577 1.00 52.57  ? 35  GLN B NE2 1 
ATOM   3980  N N   . ILE B 1 36  ? 130.387 152.406 161.925 1.00 50.83  ? 36  ILE B N   1 
ATOM   3981  C CA  . ILE B 1 36  ? 131.110 152.438 163.190 1.00 50.83  ? 36  ILE B CA  1 
ATOM   3982  C C   . ILE B 1 36  ? 132.209 153.485 163.083 1.00 50.83  ? 36  ILE B C   1 
ATOM   3983  O O   . ILE B 1 36  ? 132.897 153.576 162.061 1.00 50.83  ? 36  ILE B O   1 
ATOM   3984  C CB  . ILE B 1 36  ? 131.681 151.051 163.557 1.00 50.83  ? 36  ILE B CB  1 
ATOM   3985  C CG1 . ILE B 1 36  ? 132.593 151.145 164.780 1.00 50.83  ? 36  ILE B CG1 1 
ATOM   3986  C CG2 . ILE B 1 36  ? 132.419 150.440 162.378 1.00 50.83  ? 36  ILE B CG2 1 
ATOM   3987  C CD1 . ILE B 1 36  ? 132.618 149.886 165.609 1.00 50.83  ? 36  ILE B CD1 1 
ATOM   3988  N N   . GLU B 1 37  ? 132.368 154.285 164.132 1.00 53.10  ? 37  GLU B N   1 
ATOM   3989  C CA  . GLU B 1 37  ? 133.335 155.374 164.148 1.00 53.10  ? 37  GLU B CA  1 
ATOM   3990  C C   . GLU B 1 37  ? 134.632 154.910 164.797 1.00 53.10  ? 37  GLU B C   1 
ATOM   3991  O O   . GLU B 1 37  ? 134.619 154.369 165.906 1.00 53.10  ? 37  GLU B O   1 
ATOM   3992  C CB  . GLU B 1 37  ? 132.775 156.588 164.891 1.00 53.10  ? 37  GLU B CB  1 
ATOM   3993  C CG  . GLU B 1 37  ? 133.522 157.879 164.608 1.00 53.10  ? 37  GLU B CG  1 
ATOM   3994  C CD  . GLU B 1 37  ? 133.132 159.002 165.547 1.00 53.10  ? 37  GLU B CD  1 
ATOM   3995  O OE1 . GLU B 1 37  ? 131.919 159.228 165.736 1.00 53.10  ? 37  GLU B OE1 1 
ATOM   3996  O OE2 . GLU B 1 37  ? 134.039 159.658 166.100 1.00 53.10  ? 37  GLU B OE2 1 
ATOM   3997  N N   . VAL B 1 38  ? 135.746 155.133 164.104 1.00 50.89  ? 38  VAL B N   1 
ATOM   3998  C CA  . VAL B 1 38  ? 137.066 154.746 164.575 1.00 50.89  ? 38  VAL B CA  1 
ATOM   3999  C C   . VAL B 1 38  ? 137.955 155.985 164.611 1.00 50.89  ? 38  VAL B C   1 
ATOM   4000  O O   . VAL B 1 38  ? 137.595 157.053 164.116 1.00 50.89  ? 38  VAL B O   1 
ATOM   4001  C CB  . VAL B 1 38  ? 137.697 153.639 163.707 1.00 50.89  ? 38  VAL B CB  1 
ATOM   4002  C CG1 . VAL B 1 38  ? 136.863 152.375 163.779 1.00 50.89  ? 38  VAL B CG1 1 
ATOM   4003  C CG2 . VAL B 1 38  ? 137.837 154.105 162.272 1.00 50.89  ? 38  VAL B CG2 1 
ATOM   4004  N N   . THR B 1 39  ? 139.138 155.821 165.206 1.00 52.49  ? 39  THR B N   1 
ATOM   4005  C CA  . THR B 1 39  ? 140.039 156.944 165.426 1.00 52.49  ? 39  THR B CA  1 
ATOM   4006  C C   . THR B 1 39  ? 140.891 157.286 164.210 1.00 52.49  ? 39  THR B C   1 
ATOM   4007  O O   . THR B 1 39  ? 141.460 158.381 164.166 1.00 52.49  ? 39  THR B O   1 
ATOM   4008  C CB  . THR B 1 39  ? 140.959 156.658 166.617 1.00 52.49  ? 39  THR B CB  1 
ATOM   4009  O OG1 . THR B 1 39  ? 141.767 155.509 166.338 1.00 52.49  ? 39  THR B OG1 1 
ATOM   4010  C CG2 . THR B 1 39  ? 140.145 156.400 167.871 1.00 52.49  ? 39  THR B CG2 1 
ATOM   4011  N N   . ASN B 1 40  ? 140.987 156.396 163.224 1.00 49.40  ? 40  ASN B N   1 
ATOM   4012  C CA  . ASN B 1 40  ? 141.847 156.638 162.074 1.00 49.40  ? 40  ASN B CA  1 
ATOM   4013  C C   . ASN B 1 40  ? 141.483 155.659 160.966 1.00 49.40  ? 40  ASN B C   1 
ATOM   4014  O O   . ASN B 1 40  ? 141.135 154.510 161.243 1.00 49.40  ? 40  ASN B O   1 
ATOM   4015  C CB  . ASN B 1 40  ? 143.326 156.493 162.463 1.00 49.40  ? 40  ASN B CB  1 
ATOM   4016  C CG  . ASN B 1 40  ? 144.262 157.134 161.462 1.00 49.40  ? 40  ASN B CG  1 
ATOM   4017  O OD1 . ASN B 1 40  ? 143.882 158.043 160.727 1.00 49.40  ? 40  ASN B OD1 1 
ATOM   4018  N ND2 . ASN B 1 40  ? 145.499 156.657 161.432 1.00 49.40  ? 40  ASN B ND2 1 
ATOM   4019  N N   . ALA B 1 41  ? 141.563 156.122 159.718 1.00 42.40  ? 41  ALA B N   1 
ATOM   4020  C CA  . ALA B 1 41  ? 141.234 155.296 158.563 1.00 42.40  ? 41  ALA B CA  1 
ATOM   4021  C C   . ALA B 1 41  ? 141.995 155.800 157.344 1.00 42.40  ? 41  ALA B C   1 
ATOM   4022  O O   . ALA B 1 41  ? 142.473 156.936 157.312 1.00 42.40  ? 41  ALA B O   1 
ATOM   4023  C CB  . ALA B 1 41  ? 139.729 155.289 158.280 1.00 42.40  ? 41  ALA B CB  1 
ATOM   4024  N N   . THR B 1 42  ? 142.099 154.935 156.334 1.00 38.41  ? 42  THR B N   1 
ATOM   4025  C CA  . THR B 1 42  ? 142.797 155.254 155.094 1.00 38.41  ? 42  THR B CA  1 
ATOM   4026  C C   . THR B 1 42  ? 141.910 154.960 153.891 1.00 38.41  ? 42  THR B C   1 
ATOM   4027  O O   . THR B 1 42  ? 141.085 154.044 153.914 1.00 38.41  ? 42  THR B O   1 
ATOM   4028  C CB  . THR B 1 42  ? 144.112 154.465 154.953 1.00 38.41  ? 42  THR B CB  1 
ATOM   4029  O OG1 . THR B 1 42  ? 143.823 153.083 154.716 1.00 38.41  ? 42  THR B OG1 1 
ATOM   4030  C CG2 . THR B 1 42  ? 144.963 154.595 156.203 1.00 38.41  ? 42  THR B CG2 1 
ATOM   4031  N N   . GLU B 1 43  ? 142.100 155.741 152.831 1.00 33.88  ? 43  GLU B N   1 
ATOM   4032  C CA  . GLU B 1 43  ? 141.348 155.578 151.592 1.00 33.88  ? 43  GLU B CA  1 
ATOM   4033  C C   . GLU B 1 43  ? 142.070 154.600 150.673 1.00 33.88  ? 43  GLU B C   1 
ATOM   4034  O O   . GLU B 1 43  ? 143.285 154.700 150.482 1.00 33.88  ? 43  GLU B O   1 
ATOM   4035  C CB  . GLU B 1 43  ? 141.163 156.926 150.895 1.00 33.88  ? 43  GLU B CB  1 
ATOM   4036  C CG  . GLU B 1 43  ? 140.615 156.823 149.486 1.00 33.88  ? 43  GLU B CG  1 
ATOM   4037  C CD  . GLU B 1 43  ? 139.207 156.266 149.447 1.00 33.88  ? 43  GLU B CD  1 
ATOM   4038  O OE1 . GLU B 1 43  ? 138.322 156.831 150.120 1.00 33.88  ? 43  GLU B OE1 1 
ATOM   4039  O OE2 . GLU B 1 43  ? 138.985 155.257 148.750 1.00 33.88  ? 43  GLU B OE2 1 
ATOM   4040  N N   . LEU B 1 44  ? 141.319 153.657 150.103 1.00 31.61  ? 44  LEU B N   1 
ATOM   4041  C CA  . LEU B 1 44  ? 141.901 152.590 149.300 1.00 31.61  ? 44  LEU B CA  1 
ATOM   4042  C C   . LEU B 1 44  ? 141.696 152.745 147.797 1.00 31.61  ? 44  LEU B C   1 
ATOM   4043  O O   . LEU B 1 44  ? 142.270 151.960 147.037 1.00 31.61  ? 44  LEU B O   1 
ATOM   4044  C CB  . LEU B 1 44  ? 141.336 151.230 149.737 1.00 31.61  ? 44  LEU B CB  1 
ATOM   4045  C CG  . LEU B 1 44  ? 141.749 150.691 151.109 1.00 31.61  ? 44  LEU B CG  1 
ATOM   4046  C CD1 . LEU B 1 44  ? 141.224 149.281 151.300 1.00 31.61  ? 44  LEU B CD1 1 
ATOM   4047  C CD2 . LEU B 1 44  ? 143.257 150.733 151.294 1.00 31.61  ? 44  LEU B CD2 1 
ATOM   4048  N N   . VAL B 1 45  ? 140.910 153.720 147.343 1.00 29.40  ? 45  VAL B N   1 
ATOM   4049  C CA  . VAL B 1 45  ? 140.608 153.898 145.925 1.00 29.40  ? 45  VAL B CA  1 
ATOM   4050  C C   . VAL B 1 45  ? 141.197 155.221 145.454 1.00 29.40  ? 45  VAL B C   1 
ATOM   4051  O O   . VAL B 1 45  ? 140.944 156.271 146.055 1.00 29.40  ? 45  VAL B O   1 
ATOM   4052  C CB  . VAL B 1 45  ? 139.093 153.850 145.655 1.00 29.40  ? 45  VAL B CB  1 
ATOM   4053  C CG1 . VAL B 1 45  ? 138.812 153.978 144.165 1.00 29.40  ? 45  VAL B CG1 1 
ATOM   4054  C CG2 . VAL B 1 45  ? 138.493 152.567 146.200 1.00 29.40  ? 45  VAL B CG2 1 
ATOM   4055  N N   . GLN B 1 46  ? 141.981 155.168 144.379 1.00 29.04  ? 46  GLN B N   1 
ATOM   4056  C CA  . GLN B 1 46  ? 142.519 156.360 143.733 1.00 29.04  ? 46  GLN B CA  1 
ATOM   4057  C C   . GLN B 1 46  ? 141.500 156.858 142.713 1.00 29.04  ? 46  GLN B C   1 
ATOM   4058  O O   . GLN B 1 46  ? 141.099 156.110 141.817 1.00 29.04  ? 46  GLN B O   1 
ATOM   4059  C CB  . GLN B 1 46  ? 143.859 156.047 143.067 1.00 29.04  ? 46  GLN B CB  1 
ATOM   4060  C CG  . GLN B 1 46  ? 144.422 157.156 142.194 1.00 29.04  ? 46  GLN B CG  1 
ATOM   4061  C CD  . GLN B 1 46  ? 145.002 158.301 142.999 1.00 29.04  ? 46  GLN B CD  1 
ATOM   4062  O OE1 . GLN B 1 46  ? 145.779 158.093 143.926 1.00 29.04  ? 46  GLN B OE1 1 
ATOM   4063  N NE2 . GLN B 1 46  ? 144.625 159.520 142.645 1.00 29.04  ? 46  GLN B NE2 1 
ATOM   4064  N N   . ASN B 1 47  ? 141.079 158.117 142.847 1.00 30.47  ? 47  ASN B N   1 
ATOM   4065  C CA  . ASN B 1 47  ? 139.957 158.631 142.069 1.00 30.47  ? 47  ASN B CA  1 
ATOM   4066  C C   . ASN B 1 47  ? 140.291 159.898 141.286 1.00 30.47  ? 47  ASN B C   1 
ATOM   4067  O O   . ASN B 1 47  ? 139.378 160.597 140.841 1.00 30.47  ? 47  ASN B O   1 
ATOM   4068  C CB  . ASN B 1 47  ? 138.749 158.878 142.979 1.00 30.47  ? 47  ASN B CB  1 
ATOM   4069  C CG  . ASN B 1 47  ? 138.921 160.094 143.879 1.00 30.47  ? 47  ASN B CG  1 
ATOM   4070  O OD1 . ASN B 1 47  ? 140.028 160.588 144.083 1.00 30.47  ? 47  ASN B OD1 1 
ATOM   4071  N ND2 . ASN B 1 47  ? 137.815 160.579 144.424 1.00 30.47  ? 47  ASN B ND2 1 
ATOM   4072  N N   . SER B 1 48  ? 141.570 160.216 141.100 1.00 31.82  ? 48  SER B N   1 
ATOM   4073  C CA  . SER B 1 48  ? 141.921 161.452 140.414 1.00 31.82  ? 48  SER B CA  1 
ATOM   4074  C C   . SER B 1 48  ? 143.246 161.290 139.686 1.00 31.82  ? 48  SER B C   1 
ATOM   4075  O O   . SER B 1 48  ? 144.041 160.397 139.985 1.00 31.82  ? 48  SER B O   1 
ATOM   4076  C CB  . SER B 1 48  ? 141.990 162.634 141.391 1.00 31.82  ? 48  SER B CB  1 
ATOM   4077  O OG  . SER B 1 48  ? 142.926 162.387 142.423 1.00 31.82  ? 48  SER B OG  1 
ATOM   4078  N N   . SER B 1 49  ? 143.467 162.176 138.716 1.00 33.64  ? 49  SER B N   1 
ATOM   4079  C CA  . SER B 1 49  ? 144.692 162.216 137.933 1.00 33.64  ? 49  SER B CA  1 
ATOM   4080  C C   . SER B 1 49  ? 145.092 163.666 137.708 1.00 33.64  ? 49  SER B C   1 
ATOM   4081  O O   . SER B 1 49  ? 144.244 164.562 137.699 1.00 33.64  ? 49  SER B O   1 
ATOM   4082  C CB  . SER B 1 49  ? 144.521 161.500 136.587 1.00 33.64  ? 49  SER B CB  1 
ATOM   4083  O OG  . SER B 1 49  ? 145.706 161.565 135.819 1.00 33.64  ? 49  SER B OG  1 
ATOM   4084  N N   . THR B 1 50  ? 146.394 163.895 137.528 1.00 36.02  ? 50  THR B N   1 
ATOM   4085  C CA  . THR B 1 50  ? 146.875 165.238 137.223 1.00 36.02  ? 50  THR B CA  1 
ATOM   4086  C C   . THR B 1 50  ? 146.576 165.662 135.791 1.00 36.02  ? 50  THR B C   1 
ATOM   4087  O O   . THR B 1 50  ? 146.711 166.848 135.476 1.00 36.02  ? 50  THR B O   1 
ATOM   4088  C CB  . THR B 1 50  ? 148.381 165.342 137.476 1.00 36.02  ? 50  THR B CB  1 
ATOM   4089  O OG1 . THR B 1 50  ? 149.097 164.854 136.335 1.00 36.02  ? 50  THR B OG1 1 
ATOM   4090  C CG2 . THR B 1 50  ? 148.775 164.537 138.702 1.00 36.02  ? 50  THR B CG2 1 
ATOM   4091  N N   . GLY B 1 51  ? 146.177 164.734 134.926 1.00 34.52  ? 51  GLY B N   1 
ATOM   4092  C CA  . GLY B 1 51  ? 145.855 165.052 133.553 1.00 34.52  ? 51  GLY B CA  1 
ATOM   4093  C C   . GLY B 1 51  ? 147.021 165.079 132.592 1.00 34.52  ? 51  GLY B C   1 
ATOM   4094  O O   . GLY B 1 51  ? 146.845 165.509 131.448 1.00 34.52  ? 51  GLY B O   1 
ATOM   4095  N N   . LYS B 1 52  ? 148.203 164.637 133.013 1.00 35.15  ? 52  LYS B N   1 
ATOM   4096  C CA  . LYS B 1 52  ? 149.381 164.608 132.161 1.00 35.15  ? 52  LYS B CA  1 
ATOM   4097  C C   . LYS B 1 52  ? 149.960 163.202 132.126 1.00 35.15  ? 52  LYS B C   1 
ATOM   4098  O O   . LYS B 1 52  ? 149.806 162.425 133.072 1.00 35.15  ? 52  LYS B O   1 
ATOM   4099  C CB  . LYS B 1 52  ? 150.453 165.588 132.649 1.00 35.15  ? 52  LYS B CB  1 
ATOM   4100  C CG  . LYS B 1 52  ? 149.914 166.905 133.171 1.00 35.15  ? 52  LYS B CG  1 
ATOM   4101  C CD  . LYS B 1 52  ? 149.348 167.749 132.050 1.00 35.15  ? 52  LYS B CD  1 
ATOM   4102  C CE  . LYS B 1 52  ? 149.701 169.214 132.230 1.00 35.15  ? 52  LYS B CE  1 
ATOM   4103  N NZ  . LYS B 1 52  ? 149.969 169.549 133.653 1.00 35.15  ? 52  LYS B NZ  1 
ATOM   4104  N N   . ILE B 1 53  ? 150.633 162.882 131.027 1.00 34.08  ? 53  ILE B N   1 
ATOM   4105  C CA  . ILE B 1 53  ? 151.316 161.604 130.864 1.00 34.08  ? 53  ILE B CA  1 
ATOM   4106  C C   . ILE B 1 53  ? 152.806 161.833 131.076 1.00 34.08  ? 53  ILE B C   1 
ATOM   4107  O O   . ILE B 1 53  ? 153.421 162.651 130.385 1.00 34.08  ? 53  ILE B O   1 
ATOM   4108  C CB  . ILE B 1 53  ? 151.037 160.988 129.483 1.00 34.08  ? 53  ILE B CB  1 
ATOM   4109  C CG1 . ILE B 1 53  ? 149.552 160.650 129.344 1.00 34.08  ? 53  ILE B CG1 1 
ATOM   4110  C CG2 . ILE B 1 53  ? 151.896 159.751 129.264 1.00 34.08  ? 53  ILE B CG2 1 
ATOM   4111  C CD1 . ILE B 1 53  ? 149.145 160.227 127.957 1.00 34.08  ? 53  ILE B CD1 1 
ATOM   4112  N N   . CYS B 1 54  ? 153.382 161.117 132.036 1.00 37.43  ? 54  CYS B N   1 
ATOM   4113  C CA  . CYS B 1 54  ? 154.801 161.243 132.337 1.00 37.43  ? 54  CYS B CA  1 
ATOM   4114  C C   . CYS B 1 54  ? 155.634 160.463 131.328 1.00 37.43  ? 54  CYS B C   1 
ATOM   4115  O O   . CYS B 1 54  ? 155.254 159.371 130.900 1.00 37.43  ? 54  CYS B O   1 
ATOM   4116  C CB  . CYS B 1 54  ? 155.090 160.744 133.753 1.00 37.43  ? 54  CYS B CB  1 
ATOM   4117  S SG  . CYS B 1 54  ? 154.443 161.803 135.071 1.00 37.43  ? 54  CYS B SG  1 
ATOM   4118  N N   . ASN B 1 55  ? 156.784 161.024 130.959 1.00 38.04  ? 55  ASN B N   1 
ATOM   4119  C CA  . ASN B 1 55  ? 157.641 160.427 129.942 1.00 38.04  ? 55  ASN B CA  1 
ATOM   4120  C C   . ASN B 1 55  ? 158.673 159.459 130.509 1.00 38.04  ? 55  ASN B C   1 
ATOM   4121  O O   . ASN B 1 55  ? 159.510 158.960 129.752 1.00 38.04  ? 55  ASN B O   1 
ATOM   4122  C CB  . ASN B 1 55  ? 158.343 161.522 129.128 1.00 38.04  ? 55  ASN B CB  1 
ATOM   4123  C CG  . ASN B 1 55  ? 159.278 162.381 129.964 1.00 38.04  ? 55  ASN B CG  1 
ATOM   4124  O OD1 . ASN B 1 55  ? 159.391 162.211 131.176 1.00 38.04  ? 55  ASN B OD1 1 
ATOM   4125  N ND2 . ASN B 1 55  ? 159.955 163.314 129.310 1.00 38.04  ? 55  ASN B ND2 1 
ATOM   4126  N N   . ASN B 1 56  ? 158.643 159.184 131.808 1.00 37.04  ? 56  ASN B N   1 
ATOM   4127  C CA  . ASN B 1 56  ? 159.534 158.215 132.424 1.00 37.04  ? 56  ASN B CA  1 
ATOM   4128  C C   . ASN B 1 56  ? 158.734 157.333 133.369 1.00 37.04  ? 56  ASN B C   1 
ATOM   4129  O O   . ASN B 1 56  ? 157.770 157.800 133.986 1.00 37.04  ? 56  ASN B O   1 
ATOM   4130  C CB  . ASN B 1 56  ? 160.673 158.905 133.189 1.00 37.04  ? 56  ASN B CB  1 
ATOM   4131  C CG  . ASN B 1 56  ? 161.896 159.126 132.327 1.00 37.04  ? 56  ASN B CG  1 
ATOM   4132  O OD1 . ASN B 1 56  ? 162.485 158.176 131.813 1.00 37.04  ? 56  ASN B OD1 1 
ATOM   4133  N ND2 . ASN B 1 56  ? 162.286 160.383 132.162 1.00 37.04  ? 56  ASN B ND2 1 
ATOM   4134  N N   . PRO B 1 57  ? 159.116 156.053 133.515 1.00 34.17  ? 57  PRO B N   1 
ATOM   4135  C CA  . PRO B 1 57  ? 160.263 155.402 132.876 1.00 34.17  ? 57  PRO B CA  1 
ATOM   4136  C C   . PRO B 1 57  ? 159.972 154.781 131.508 1.00 34.17  ? 57  PRO B C   1 
ATOM   4137  O O   . PRO B 1 57  ? 160.910 154.366 130.833 1.00 34.17  ? 57  PRO B O   1 
ATOM   4138  C CB  . PRO B 1 57  ? 160.625 154.314 133.881 1.00 34.17  ? 57  PRO B CB  1 
ATOM   4139  C CG  . PRO B 1 57  ? 159.307 153.898 134.425 1.00 34.17  ? 57  PRO B CG  1 
ATOM   4140  C CD  . PRO B 1 57  ? 158.437 155.138 134.449 1.00 34.17  ? 57  PRO B CD  1 
ATOM   4141  N N   . HIS B 1 58  ? 158.706 154.711 131.110 1.00 32.27  ? 58  HIS B N   1 
ATOM   4142  C CA  . HIS B 1 58  ? 158.352 154.147 129.816 1.00 32.27  ? 58  HIS B CA  1 
ATOM   4143  C C   . HIS B 1 58  ? 158.691 155.121 128.694 1.00 32.27  ? 58  HIS B C   1 
ATOM   4144  O O   . HIS B 1 58  ? 158.719 156.339 128.887 1.00 32.27  ? 58  HIS B O   1 
ATOM   4145  C CB  . HIS B 1 58  ? 156.863 153.801 129.767 1.00 32.27  ? 58  HIS B CB  1 
ATOM   4146  C CG  . HIS B 1 58  ? 156.398 152.956 130.912 1.00 32.27  ? 58  HIS B CG  1 
ATOM   4147  N ND1 . HIS B 1 58  ? 156.807 151.653 131.090 1.00 32.27  ? 58  HIS B ND1 1 
ATOM   4148  C CD2 . HIS B 1 58  ? 155.550 153.226 131.932 1.00 32.27  ? 58  HIS B CD2 1 
ATOM   4149  C CE1 . HIS B 1 58  ? 156.236 151.158 132.173 1.00 32.27  ? 58  HIS B CE1 1 
ATOM   4150  N NE2 . HIS B 1 58  ? 155.469 152.093 132.702 1.00 32.27  ? 58  HIS B NE2 1 
ATOM   4151  N N   . LYS B 1 59  ? 158.951 154.572 127.511 1.00 29.62  ? 59  LYS B N   1 
ATOM   4152  C CA  . LYS B 1 59  ? 159.201 155.378 126.320 1.00 29.62  ? 59  LYS B CA  1 
ATOM   4153  C C   . LYS B 1 59  ? 157.867 155.652 125.635 1.00 29.62  ? 59  LYS B C   1 
ATOM   4154  O O   . LYS B 1 59  ? 157.258 154.748 125.056 1.00 29.62  ? 59  LYS B O   1 
ATOM   4155  C CB  . LYS B 1 59  ? 160.173 154.676 125.376 1.00 29.62  ? 59  LYS B CB  1 
ATOM   4156  C CG  . LYS B 1 59  ? 160.654 155.549 124.226 1.00 29.62  ? 59  LYS B CG  1 
ATOM   4157  C CD  . LYS B 1 59  ? 161.572 154.780 123.292 1.00 29.62  ? 59  LYS B CD  1 
ATOM   4158  C CE  . LYS B 1 59  ? 162.382 155.713 122.406 1.00 29.62  ? 59  LYS B CE  1 
ATOM   4159  N NZ  . LYS B 1 59  ? 161.520 156.575 121.550 1.00 29.62  ? 59  LYS B NZ  1 
ATOM   4160  N N   . VAL B 1 60  ? 157.415 156.899 125.703 1.00 28.51  ? 60  VAL B N   1 
ATOM   4161  C CA  . VAL B 1 60  ? 156.136 157.313 125.139 1.00 28.51  ? 60  VAL B CA  1 
ATOM   4162  C C   . VAL B 1 60  ? 156.401 158.063 123.843 1.00 28.51  ? 60  VAL B C   1 
ATOM   4163  O O   . VAL B 1 60  ? 157.219 158.990 123.809 1.00 28.51  ? 60  VAL B O   1 
ATOM   4164  C CB  . VAL B 1 60  ? 155.348 158.184 126.133 1.00 28.51  ? 60  VAL B CB  1 
ATOM   4165  C CG1 . VAL B 1 60  ? 154.018 158.607 125.537 1.00 28.51  ? 60  VAL B CG1 1 
ATOM   4166  C CG2 . VAL B 1 60  ? 155.136 157.438 127.439 1.00 28.51  ? 60  VAL B CG2 1 
ATOM   4167  N N   . LEU B 1 61  ? 155.719 157.660 122.773 1.00 27.98  ? 61  LEU B N   1 
ATOM   4168  C CA  . LEU B 1 61  ? 155.869 158.279 121.461 1.00 27.98  ? 61  LEU B CA  1 
ATOM   4169  C C   . LEU B 1 61  ? 154.549 158.923 121.063 1.00 27.98  ? 61  LEU B C   1 
ATOM   4170  O O   . LEU B 1 61  ? 153.529 158.236 120.946 1.00 27.98  ? 61  LEU B O   1 
ATOM   4171  C CB  . LEU B 1 61  ? 156.309 157.250 120.418 1.00 27.98  ? 61  LEU B CB  1 
ATOM   4172  C CG  . LEU B 1 61  ? 156.519 157.750 118.988 1.00 27.98  ? 61  LEU B CG  1 
ATOM   4173  C CD1 . LEU B 1 61  ? 157.557 158.858 118.953 1.00 27.98  ? 61  LEU B CD1 1 
ATOM   4174  C CD2 . LEU B 1 61  ? 156.925 156.606 118.077 1.00 27.98  ? 61  LEU B CD2 1 
ATOM   4175  N N   . ASP B 1 62  ? 154.575 160.235 120.847 1.00 29.93  ? 62  ASP B N   1 
ATOM   4176  C CA  . ASP B 1 62  ? 153.379 160.985 120.484 1.00 29.93  ? 62  ASP B CA  1 
ATOM   4177  C C   . ASP B 1 62  ? 153.150 160.882 118.980 1.00 29.93  ? 62  ASP B C   1 
ATOM   4178  O O   . ASP B 1 62  ? 153.993 161.313 118.187 1.00 29.93  ? 62  ASP B O   1 
ATOM   4179  C CB  . ASP B 1 62  ? 153.526 162.444 120.912 1.00 29.93  ? 62  ASP B CB  1 
ATOM   4180  C CG  . ASP B 1 62  ? 152.229 163.225 120.811 1.00 29.93  ? 62  ASP B CG  1 
ATOM   4181  O OD1 . ASP B 1 62  ? 151.219 162.675 120.333 1.00 29.93  ? 62  ASP B OD1 1 
ATOM   4182  O OD2 . ASP B 1 62  ? 152.219 164.403 121.220 1.00 29.93  ? 62  ASP B OD2 1 
ATOM   4183  N N   . GLY B 1 63  ? 152.005 160.320 118.588 1.00 30.68  ? 63  GLY B N   1 
ATOM   4184  C CA  . GLY B 1 63  ? 151.680 160.191 117.179 1.00 30.68  ? 63  GLY B CA  1 
ATOM   4185  C C   . GLY B 1 63  ? 151.263 161.487 116.518 1.00 30.68  ? 63  GLY B C   1 
ATOM   4186  O O   . GLY B 1 63  ? 151.300 161.578 115.287 1.00 30.68  ? 63  GLY B O   1 
ATOM   4187  N N   . ARG B 1 64  ? 150.866 162.485 117.309 1.00 32.69  ? 64  ARG B N   1 
ATOM   4188  C CA  . ARG B 1 64  ? 150.450 163.796 116.820 1.00 32.69  ? 64  ARG B CA  1 
ATOM   4189  C C   . ARG B 1 64  ? 149.309 163.684 115.814 1.00 32.69  ? 64  ARG B C   1 
ATOM   4190  O O   . ARG B 1 64  ? 148.196 163.297 116.178 1.00 32.69  ? 64  ARG B O   1 
ATOM   4191  C CB  . ARG B 1 64  ? 151.644 164.543 116.223 1.00 32.69  ? 64  ARG B CB  1 
ATOM   4192  C CG  . ARG B 1 64  ? 152.813 164.639 117.187 1.00 32.69  ? 64  ARG B CG  1 
ATOM   4193  C CD  . ARG B 1 64  ? 153.815 165.701 116.784 1.00 32.69  ? 64  ARG B CD  1 
ATOM   4194  N NE  . ARG B 1 64  ? 154.351 166.395 117.949 1.00 32.69  ? 64  ARG B NE  1 
ATOM   4195  C CZ  . ARG B 1 64  ? 155.230 165.879 118.797 1.00 32.69  ? 64  ARG B CZ  1 
ATOM   4196  N NH1 . ARG B 1 64  ? 155.727 164.664 118.626 1.00 32.69  ? 64  ARG B NH1 1 
ATOM   4197  N NH2 . ARG B 1 64  ? 155.623 166.600 119.843 1.00 32.69  ? 64  ARG B NH2 1 
ATOM   4198  N N   . ASP B 1 65  ? 149.566 164.011 114.548 1.00 33.69  ? 65  ASP B N   1 
ATOM   4199  C CA  . ASP B 1 65  ? 148.527 163.988 113.528 1.00 33.69  ? 65  ASP B CA  1 
ATOM   4200  C C   . ASP B 1 65  ? 148.578 162.736 112.656 1.00 33.69  ? 65  ASP B C   1 
ATOM   4201  O O   . ASP B 1 65  ? 147.991 162.723 111.570 1.00 33.69  ? 65  ASP B O   1 
ATOM   4202  C CB  . ASP B 1 65  ? 148.612 165.246 112.662 1.00 33.69  ? 65  ASP B CB  1 
ATOM   4203  C CG  . ASP B 1 65  ? 149.983 165.448 112.056 1.00 33.69  ? 65  ASP B CG  1 
ATOM   4204  O OD1 . ASP B 1 65  ? 150.979 165.007 112.666 1.00 33.69  ? 65  ASP B OD1 1 
ATOM   4205  O OD2 . ASP B 1 65  ? 150.067 166.050 110.967 1.00 33.69  ? 65  ASP B OD2 1 
ATOM   4206  N N   . CYS B 1 66  ? 149.247 161.679 113.115 1.00 32.37  ? 66  CYS B N   1 
ATOM   4207  C CA  . CYS B 1 66  ? 149.410 160.452 112.348 1.00 32.37  ? 66  CYS B CA  1 
ATOM   4208  C C   . CYS B 1 66  ? 148.919 159.251 113.145 1.00 32.37  ? 66  CYS B C   1 
ATOM   4209  O O   . CYS B 1 66  ? 149.172 159.150 114.348 1.00 32.37  ? 66  CYS B O   1 
ATOM   4210  C CB  . CYS B 1 66  ? 150.877 160.235 111.957 1.00 32.37  ? 66  CYS B CB  1 
ATOM   4211  S SG  . CYS B 1 66  ? 151.502 161.359 110.694 1.00 32.37  ? 66  CYS B SG  1 
ATOM   4212  N N   . THR B 1 67  ? 148.224 158.340 112.468 1.00 27.97  ? 67  THR B N   1 
ATOM   4213  C CA  . THR B 1 67  ? 147.924 157.041 113.050 1.00 27.97  ? 67  THR B CA  1 
ATOM   4214  C C   . THR B 1 67  ? 149.112 156.100 112.860 1.00 27.97  ? 67  THR B C   1 
ATOM   4215  O O   . THR B 1 67  ? 150.056 156.390 112.123 1.00 27.97  ? 67  THR B O   1 
ATOM   4216  C CB  . THR B 1 67  ? 146.664 156.438 112.428 1.00 27.97  ? 67  THR B CB  1 
ATOM   4217  O OG1 . THR B 1 67  ? 146.900 156.146 111.045 1.00 27.97  ? 67  THR B OG1 1 
ATOM   4218  C CG2 . THR B 1 67  ? 145.492 157.398 112.546 1.00 27.97  ? 67  THR B CG2 1 
ATOM   4219  N N   . LEU B 1 68  ? 149.063 154.956 113.547 1.00 26.05  ? 68  LEU B N   1 
ATOM   4220  C CA  . LEU B 1 68  ? 150.152 153.989 113.442 1.00 26.05  ? 68  LEU B CA  1 
ATOM   4221  C C   . LEU B 1 68  ? 150.224 153.372 112.047 1.00 26.05  ? 68  LEU B C   1 
ATOM   4222  O O   . LEU B 1 68  ? 151.318 153.186 111.503 1.00 26.05  ? 68  LEU B O   1 
ATOM   4223  C CB  . LEU B 1 68  ? 150.000 152.904 114.509 1.00 26.05  ? 68  LEU B CB  1 
ATOM   4224  C CG  . LEU B 1 68  ? 151.101 151.839 114.549 1.00 26.05  ? 68  LEU B CG  1 
ATOM   4225  C CD1 . LEU B 1 68  ? 152.466 152.473 114.771 1.00 26.05  ? 68  LEU B CD1 1 
ATOM   4226  C CD2 . LEU B 1 68  ? 150.815 150.789 115.608 1.00 26.05  ? 68  LEU B CD2 1 
ATOM   4227  N N   . ILE B 1 69  ? 149.072 153.053 111.450 1.00 25.57  ? 69  ILE B N   1 
ATOM   4228  C CA  . ILE B 1 69  ? 149.062 152.450 110.119 1.00 25.57  ? 69  ILE B CA  1 
ATOM   4229  C C   . ILE B 1 69  ? 149.600 153.425 109.076 1.00 25.57  ? 69  ILE B C   1 
ATOM   4230  O O   . ILE B 1 69  ? 150.364 153.038 108.184 1.00 25.57  ? 69  ILE B O   1 
ATOM   4231  C CB  . ILE B 1 69  ? 147.645 151.961 109.763 1.00 25.57  ? 69  ILE B CB  1 
ATOM   4232  C CG1 . ILE B 1 69  ? 147.179 150.898 110.759 1.00 25.57  ? 69  ILE B CG1 1 
ATOM   4233  C CG2 . ILE B 1 69  ? 147.603 151.408 108.346 1.00 25.57  ? 69  ILE B CG2 1 
ATOM   4234  C CD1 . ILE B 1 69  ? 147.901 149.582 110.632 1.00 25.57  ? 69  ILE B CD1 1 
ATOM   4235  N N   . ASP B 1 70  ? 149.208 154.698 109.165 1.00 27.57  ? 70  ASP B N   1 
ATOM   4236  C CA  . ASP B 1 70  ? 149.688 155.693 108.209 1.00 27.57  ? 70  ASP B CA  1 
ATOM   4237  C C   . ASP B 1 70  ? 151.194 155.896 108.327 1.00 27.57  ? 70  ASP B C   1 
ATOM   4238  O O   . ASP B 1 70  ? 151.883 156.075 107.317 1.00 27.57  ? 70  ASP B O   1 
ATOM   4239  C CB  . ASP B 1 70  ? 148.949 157.016 108.411 1.00 27.57  ? 70  ASP B CB  1 
ATOM   4240  C CG  . ASP B 1 70  ? 147.644 157.073 107.650 1.00 27.57  ? 70  ASP B CG  1 
ATOM   4241  O OD1 . ASP B 1 70  ? 147.551 156.436 106.582 1.00 27.57  ? 70  ASP B OD1 1 
ATOM   4242  O OD2 . ASP B 1 70  ? 146.707 157.750 108.118 1.00 27.57  ? 70  ASP B OD2 1 
ATOM   4243  N N   . ALA B 1 71  ? 151.721 155.885 109.553 1.00 26.49  ? 71  ALA B N   1 
ATOM   4244  C CA  . ALA B 1 71  ? 153.164 155.981 109.735 1.00 26.49  ? 71  ALA B CA  1 
ATOM   4245  C C   . ALA B 1 71  ? 153.879 154.737 109.225 1.00 26.49  ? 71  ALA B C   1 
ATOM   4246  O O   . ALA B 1 71  ? 154.996 154.834 108.710 1.00 26.49  ? 71  ALA B O   1 
ATOM   4247  C CB  . ALA B 1 71  ? 153.496 156.221 111.208 1.00 26.49  ? 71  ALA B CB  1 
ATOM   4248  N N   . MET B 1 72  ? 153.262 153.563 109.371 1.00 26.94  ? 72  MET B N   1 
ATOM   4249  C CA  . MET B 1 72  ? 153.854 152.345 108.830 1.00 26.94  ? 72  MET B CA  1 
ATOM   4250  C C   . MET B 1 72  ? 153.908 152.375 107.305 1.00 26.94  ? 72  MET B C   1 
ATOM   4251  O O   . MET B 1 72  ? 154.933 152.025 106.711 1.00 26.94  ? 72  MET B O   1 
ATOM   4252  C CB  . MET B 1 72  ? 153.074 151.126 109.320 1.00 26.94  ? 72  MET B CB  1 
ATOM   4253  C CG  . MET B 1 72  ? 153.659 149.792 108.898 1.00 26.94  ? 72  MET B CG  1 
ATOM   4254  S SD  . MET B 1 72  ? 152.906 149.151 107.394 1.00 26.94  ? 72  MET B SD  1 
ATOM   4255  C CE  . MET B 1 72  ? 151.270 148.741 107.992 1.00 26.94  ? 72  MET B CE  1 
ATOM   4256  N N   . LEU B 1 73  ? 152.820 152.800 106.654 1.00 25.52  ? 73  LEU B N   1 
ATOM   4257  C CA  . LEU B 1 73  ? 152.764 152.755 105.194 1.00 25.52  ? 73  LEU B CA  1 
ATOM   4258  C C   . LEU B 1 73  ? 153.687 153.782 104.551 1.00 25.52  ? 73  LEU B C   1 
ATOM   4259  O O   . LEU B 1 73  ? 154.237 153.527 103.476 1.00 25.52  ? 73  LEU B O   1 
ATOM   4260  C CB  . LEU B 1 73  ? 151.330 152.969 104.706 1.00 25.52  ? 73  LEU B CB  1 
ATOM   4261  C CG  . LEU B 1 73  ? 150.271 151.924 105.072 1.00 25.52  ? 73  LEU B CG  1 
ATOM   4262  C CD1 . LEU B 1 73  ? 148.902 152.360 104.579 1.00 25.52  ? 73  LEU B CD1 1 
ATOM   4263  C CD2 . LEU B 1 73  ? 150.627 150.553 104.521 1.00 25.52  ? 73  LEU B CD2 1 
ATOM   4264  N N   . GLY B 1 74  ? 153.861 154.941 105.176 1.00 27.16  ? 74  GLY B N   1 
ATOM   4265  C CA  . GLY B 1 74  ? 154.700 155.972 104.603 1.00 27.16  ? 74  GLY B CA  1 
ATOM   4266  C C   . GLY B 1 74  ? 153.932 157.146 104.032 1.00 27.16  ? 74  GLY B C   1 
ATOM   4267  O O   . GLY B 1 74  ? 154.295 157.676 102.980 1.00 27.16  ? 74  GLY B O   1 
ATOM   4268  N N   . ASP B 1 75  ? 152.859 157.542 104.709 1.00 31.10  ? 75  ASP B N   1 
ATOM   4269  C CA  . ASP B 1 75  ? 152.160 158.770 104.361 1.00 31.10  ? 75  ASP B CA  1 
ATOM   4270  C C   . ASP B 1 75  ? 153.138 159.939 104.448 1.00 31.10  ? 75  ASP B C   1 
ATOM   4271  O O   . ASP B 1 75  ? 153.869 160.050 105.440 1.00 31.10  ? 75  ASP B O   1 
ATOM   4272  C CB  . ASP B 1 75  ? 150.974 158.987 105.304 1.00 31.10  ? 75  ASP B CB  1 
ATOM   4273  C CG  . ASP B 1 75  ? 149.968 159.995 104.774 1.00 31.10  ? 75  ASP B CG  1 
ATOM   4274  O OD1 . ASP B 1 75  ? 150.343 161.157 104.530 1.00 31.10  ? 75  ASP B OD1 1 
ATOM   4275  O OD2 . ASP B 1 75  ? 148.788 159.627 104.619 1.00 31.10  ? 75  ASP B OD2 1 
ATOM   4276  N N   . PRO B 1 76  ? 153.202 160.807 103.433 1.00 32.73  ? 76  PRO B N   1 
ATOM   4277  C CA  . PRO B 1 76  ? 154.262 161.836 103.415 1.00 32.73  ? 76  PRO B CA  1 
ATOM   4278  C C   . PRO B 1 76  ? 154.317 162.707 104.662 1.00 32.73  ? 76  PRO B C   1 
ATOM   4279  O O   . PRO B 1 76  ? 155.404 162.915 105.219 1.00 32.73  ? 76  PRO B O   1 
ATOM   4280  C CB  . PRO B 1 76  ? 153.919 162.648 102.160 1.00 32.73  ? 76  PRO B CB  1 
ATOM   4281  C CG  . PRO B 1 76  ? 153.246 161.675 101.268 1.00 32.73  ? 76  PRO B CG  1 
ATOM   4282  C CD  . PRO B 1 76  ? 152.459 160.758 102.164 1.00 32.73  ? 76  PRO B CD  1 
ATOM   4283  N N   . HIS B 1 77  ? 153.173 163.188 105.149 1.00 32.76  ? 77  HIS B N   1 
ATOM   4284  C CA  . HIS B 1 77  ? 153.189 164.018 106.348 1.00 32.76  ? 77  HIS B CA  1 
ATOM   4285  C C   . HIS B 1 77  ? 153.522 163.227 107.609 1.00 32.76  ? 77  HIS B C   1 
ATOM   4286  O O   . HIS B 1 77  ? 153.641 163.828 108.681 1.00 32.76  ? 77  HIS B O   1 
ATOM   4287  C CB  . HIS B 1 77  ? 151.850 164.753 106.496 1.00 32.76  ? 77  HIS B CB  1 
ATOM   4288  C CG  . HIS B 1 77  ? 150.800 163.981 107.232 1.00 32.76  ? 77  HIS B CG  1 
ATOM   4289  N ND1 . HIS B 1 77  ? 150.059 162.981 106.642 1.00 32.76  ? 77  HIS B ND1 1 
ATOM   4290  C CD2 . HIS B 1 77  ? 150.346 164.083 108.503 1.00 32.76  ? 77  HIS B CD2 1 
ATOM   4291  C CE1 . HIS B 1 77  ? 149.205 162.490 107.521 1.00 32.76  ? 77  HIS B CE1 1 
ATOM   4292  N NE2 . HIS B 1 77  ? 149.357 163.143 108.658 1.00 32.76  ? 77  HIS B NE2 1 
ATOM   4293  N N   . CYS B 1 78  ? 153.685 161.909 107.503 1.00 33.55  ? 78  CYS B N   1 
ATOM   4294  C CA  . CYS B 1 78  ? 154.149 161.066 108.596 1.00 33.55  ? 78  CYS B CA  1 
ATOM   4295  C C   . CYS B 1 78  ? 155.598 160.625 108.417 1.00 33.55  ? 78  CYS B C   1 
ATOM   4296  O O   . CYS B 1 78  ? 156.079 159.781 109.182 1.00 33.55  ? 78  CYS B O   1 
ATOM   4297  C CB  . CYS B 1 78  ? 153.241 159.841 108.735 1.00 33.55  ? 78  CYS B CB  1 
ATOM   4298  S SG  . CYS B 1 78  ? 151.500 160.231 109.002 1.00 33.55  ? 78  CYS B SG  1 
ATOM   4299  N N   . ASP B 1 79  ? 156.315 161.198 107.442 1.00 34.33  ? 79  ASP B N   1 
ATOM   4300  C CA  . ASP B 1 79  ? 157.663 160.733 107.122 1.00 34.33  ? 79  ASP B CA  1 
ATOM   4301  C C   . ASP B 1 79  ? 158.623 160.833 108.302 1.00 34.33  ? 79  ASP B C   1 
ATOM   4302  O O   . ASP B 1 79  ? 159.649 160.146 108.310 1.00 34.33  ? 79  ASP B O   1 
ATOM   4303  C CB  . ASP B 1 79  ? 158.231 161.522 105.942 1.00 34.33  ? 79  ASP B CB  1 
ATOM   4304  C CG  . ASP B 1 79  ? 157.765 160.990 104.601 1.00 34.33  ? 79  ASP B CG  1 
ATOM   4305  O OD1 . ASP B 1 79  ? 157.239 159.858 104.550 1.00 34.33  ? 79  ASP B OD1 1 
ATOM   4306  O OD2 . ASP B 1 79  ? 157.931 161.708 103.593 1.00 34.33  ? 79  ASP B OD2 1 
ATOM   4307  N N   . VAL B 1 80  ? 158.320 161.675 109.292 1.00 34.14  ? 80  VAL B N   1 
ATOM   4308  C CA  . VAL B 1 80  ? 159.185 161.821 110.457 1.00 34.14  ? 80  VAL B CA  1 
ATOM   4309  C C   . VAL B 1 80  ? 159.196 160.589 111.352 1.00 34.14  ? 80  VAL B C   1 
ATOM   4310  O O   . VAL B 1 80  ? 160.048 160.492 112.239 1.00 34.14  ? 80  VAL B O   1 
ATOM   4311  C CB  . VAL B 1 80  ? 158.757 163.069 111.260 1.00 34.14  ? 80  VAL B CB  1 
ATOM   4312  C CG1 . VAL B 1 80  ? 157.522 162.772 112.098 1.00 34.14  ? 80  VAL B CG1 1 
ATOM   4313  C CG2 . VAL B 1 80  ? 159.900 163.583 112.125 1.00 34.14  ? 80  VAL B CG2 1 
ATOM   4314  N N   . PHE B 1 81  ? 158.289 159.635 111.140 1.00 31.90  ? 81  PHE B N   1 
ATOM   4315  C CA  . PHE B 1 81  ? 158.176 158.474 112.015 1.00 31.90  ? 81  PHE B CA  1 
ATOM   4316  C C   . PHE B 1 81  ? 158.943 157.256 111.513 1.00 31.90  ? 81  PHE B C   1 
ATOM   4317  O O   . PHE B 1 81  ? 158.736 156.156 112.032 1.00 31.90  ? 81  PHE B O   1 
ATOM   4318  C CB  . PHE B 1 81  ? 156.704 158.110 112.218 1.00 31.90  ? 81  PHE B CB  1 
ATOM   4319  C CG  . PHE B 1 81  ? 155.968 159.055 113.116 1.00 31.90  ? 81  PHE B CG  1 
ATOM   4320  C CD1 . PHE B 1 81  ? 156.080 158.950 114.491 1.00 31.90  ? 81  PHE B CD1 1 
ATOM   4321  C CD2 . PHE B 1 81  ? 155.174 160.058 112.587 1.00 31.90  ? 81  PHE B CD2 1 
ATOM   4322  C CE1 . PHE B 1 81  ? 155.409 159.821 115.322 1.00 31.90  ? 81  PHE B CE1 1 
ATOM   4323  C CE2 . PHE B 1 81  ? 154.502 160.931 113.413 1.00 31.90  ? 81  PHE B CE2 1 
ATOM   4324  C CZ  . PHE B 1 81  ? 154.620 160.814 114.782 1.00 31.90  ? 81  PHE B CZ  1 
ATOM   4325  N N   . GLN B 1 82  ? 159.821 157.419 110.527 1.00 33.24  ? 82  GLN B N   1 
ATOM   4326  C CA  . GLN B 1 82  ? 160.530 156.277 109.965 1.00 33.24  ? 82  GLN B CA  1 
ATOM   4327  C C   . GLN B 1 82  ? 161.496 155.678 110.983 1.00 33.24  ? 82  GLN B C   1 
ATOM   4328  O O   . GLN B 1 82  ? 162.285 156.395 111.604 1.00 33.24  ? 82  GLN B O   1 
ATOM   4329  C CB  . GLN B 1 82  ? 161.284 156.691 108.703 1.00 33.24  ? 82  GLN B CB  1 
ATOM   4330  C CG  . GLN B 1 82  ? 160.394 156.874 107.486 1.00 33.24  ? 82  GLN B CG  1 
ATOM   4331  C CD  . GLN B 1 82  ? 161.175 157.237 106.243 1.00 33.24  ? 82  GLN B CD  1 
ATOM   4332  O OE1 . GLN B 1 82  ? 162.350 157.593 106.316 1.00 33.24  ? 82  GLN B OE1 1 
ATOM   4333  N NE2 . GLN B 1 82  ? 160.524 157.154 105.091 1.00 33.24  ? 82  GLN B NE2 1 
ATOM   4334  N N   . ASP B 1 83  ? 161.420 154.354 111.150 1.00 33.54  ? 83  ASP B N   1 
ATOM   4335  C CA  . ASP B 1 83  ? 162.338 153.584 111.993 1.00 33.54  ? 83  ASP B CA  1 
ATOM   4336  C C   . ASP B 1 83  ? 162.233 153.960 113.471 1.00 33.54  ? 83  ASP B C   1 
ATOM   4337  O O   . ASP B 1 83  ? 163.223 153.912 114.202 1.00 33.54  ? 83  ASP B O   1 
ATOM   4338  C CB  . ASP B 1 83  ? 163.784 153.729 111.508 1.00 33.54  ? 83  ASP B CB  1 
ATOM   4339  C CG  . ASP B 1 83  ? 164.028 153.031 110.183 1.00 33.54  ? 83  ASP B CG  1 
ATOM   4340  O OD1 . ASP B 1 83  ? 163.243 152.129 109.828 1.00 33.54  ? 83  ASP B OD1 1 
ATOM   4341  O OD2 . ASP B 1 83  ? 165.004 153.389 109.493 1.00 33.54  ? 83  ASP B OD2 1 
ATOM   4342  N N   . GLU B 1 84  ? 161.040 154.325 113.932 1.00 32.84  ? 84  GLU B N   1 
ATOM   4343  C CA  . GLU B 1 84  ? 160.855 154.706 115.324 1.00 32.84  ? 84  GLU B CA  1 
ATOM   4344  C C   . GLU B 1 84  ? 160.650 153.477 116.211 1.00 32.84  ? 84  GLU B C   1 
ATOM   4345  O O   . GLU B 1 84  ? 160.381 152.370 115.740 1.00 32.84  ? 84  GLU B O   1 
ATOM   4346  C CB  . GLU B 1 84  ? 159.671 155.662 115.465 1.00 32.84  ? 84  GLU B CB  1 
ATOM   4347  C CG  . GLU B 1 84  ? 160.017 157.120 115.223 1.00 32.84  ? 84  GLU B CG  1 
ATOM   4348  C CD  . GLU B 1 84  ? 160.553 157.812 116.461 1.00 32.84  ? 84  GLU B CD  1 
ATOM   4349  O OE1 . GLU B 1 84  ? 160.879 157.116 117.444 1.00 32.84  ? 84  GLU B OE1 1 
ATOM   4350  O OE2 . GLU B 1 84  ? 160.650 159.057 116.450 1.00 32.84  ? 84  GLU B OE2 1 
ATOM   4351  N N   . LYS B 1 85  ? 160.790 153.690 117.519 1.00 31.55  ? 85  LYS B N   1 
ATOM   4352  C CA  . LYS B 1 85  ? 160.568 152.660 118.527 1.00 31.55  ? 85  LYS B CA  1 
ATOM   4353  C C   . LYS B 1 85  ? 159.780 153.262 119.682 1.00 31.55  ? 85  LYS B C   1 
ATOM   4354  O O   . LYS B 1 85  ? 159.800 154.474 119.903 1.00 31.55  ? 85  LYS B O   1 
ATOM   4355  C CB  . LYS B 1 85  ? 161.886 152.071 119.045 1.00 31.55  ? 85  LYS B CB  1 
ATOM   4356  C CG  . LYS B 1 85  ? 162.684 151.300 118.011 1.00 31.55  ? 85  LYS B CG  1 
ATOM   4357  C CD  . LYS B 1 85  ? 164.173 151.363 118.307 1.00 31.55  ? 85  LYS B CD  1 
ATOM   4358  C CE  . LYS B 1 85  ? 164.933 152.076 117.198 1.00 31.55  ? 85  LYS B CE  1 
ATOM   4359  N NZ  . LYS B 1 85  ? 164.925 151.300 115.927 1.00 31.55  ? 85  LYS B NZ  1 
ATOM   4360  N N   . TRP B 1 86  ? 159.084 152.403 120.426 1.00 26.12  ? 86  TRP B N   1 
ATOM   4361  C CA  . TRP B 1 86  ? 158.246 152.881 121.517 1.00 26.12  ? 86  TRP B CA  1 
ATOM   4362  C C   . TRP B 1 86  ? 157.991 151.759 122.511 1.00 26.12  ? 86  TRP B C   1 
ATOM   4363  O O   . TRP B 1 86  ? 158.100 150.575 122.186 1.00 26.12  ? 86  TRP B O   1 
ATOM   4364  C CB  . TRP B 1 86  ? 156.909 153.420 120.996 1.00 26.12  ? 86  TRP B CB  1 
ATOM   4365  C CG  . TRP B 1 86  ? 156.097 152.378 120.286 1.00 26.12  ? 86  TRP B CG  1 
ATOM   4366  C CD1 . TRP B 1 86  ? 155.174 151.542 120.841 1.00 26.12  ? 86  TRP B CD1 1 
ATOM   4367  C CD2 . TRP B 1 86  ? 156.147 152.051 118.893 1.00 26.12  ? 86  TRP B CD2 1 
ATOM   4368  N NE1 . TRP B 1 86  ? 154.644 150.719 119.882 1.00 26.12  ? 86  TRP B NE1 1 
ATOM   4369  C CE2 . TRP B 1 86  ? 155.223 151.012 118.676 1.00 26.12  ? 86  TRP B CE2 1 
ATOM   4370  C CE3 . TRP B 1 86  ? 156.881 152.539 117.808 1.00 26.12  ? 86  TRP B CE3 1 
ATOM   4371  C CZ2 . TRP B 1 86  ? 155.013 150.450 117.419 1.00 26.12  ? 86  TRP B CZ2 1 
ATOM   4372  C CZ3 . TRP B 1 86  ? 156.671 151.979 116.562 1.00 26.12  ? 86  TRP B CZ3 1 
ATOM   4373  C CH2 . TRP B 1 86  ? 155.746 150.946 116.378 1.00 26.12  ? 86  TRP B CH2 1 
ATOM   4374  N N   . ASP B 1 87  ? 157.636 152.158 123.732 1.00 28.26  ? 87  ASP B N   1 
ATOM   4375  C CA  . ASP B 1 87  ? 156.956 151.289 124.684 1.00 28.26  ? 87  ASP B CA  1 
ATOM   4376  C C   . ASP B 1 87  ? 155.448 151.480 124.649 1.00 28.26  ? 87  ASP B C   1 
ATOM   4377  O O   . ASP B 1 87  ? 154.700 150.505 124.750 1.00 28.26  ? 87  ASP B O   1 
ATOM   4378  C CB  . ASP B 1 87  ? 157.466 151.538 126.108 1.00 28.26  ? 87  ASP B CB  1 
ATOM   4379  C CG  . ASP B 1 87  ? 158.824 150.919 126.362 1.00 28.26  ? 87  ASP B CG  1 
ATOM   4380  O OD1 . ASP B 1 87  ? 159.099 149.833 125.814 1.00 28.26  ? 87  ASP B OD1 1 
ATOM   4381  O OD2 . ASP B 1 87  ? 159.621 151.519 127.110 1.00 28.26  ? 87  ASP B OD2 1 
ATOM   4382  N N   . LEU B 1 88  ? 154.990 152.722 124.503 1.00 26.42  ? 88  LEU B N   1 
ATOM   4383  C CA  . LEU B 1 88  ? 153.578 153.033 124.332 1.00 26.42  ? 88  LEU B CA  1 
ATOM   4384  C C   . LEU B 1 88  ? 153.427 154.059 123.219 1.00 26.42  ? 88  LEU B C   1 
ATOM   4385  O O   . LEU B 1 88  ? 154.068 155.113 123.250 1.00 26.42  ? 88  LEU B O   1 
ATOM   4386  C CB  . LEU B 1 88  ? 152.961 153.565 125.632 1.00 26.42  ? 88  LEU B CB  1 
ATOM   4387  C CG  . LEU B 1 88  ? 151.459 153.861 125.606 1.00 26.42  ? 88  LEU B CG  1 
ATOM   4388  C CD1 . LEU B 1 88  ? 150.642 152.576 125.538 1.00 26.42  ? 88  LEU B CD1 1 
ATOM   4389  C CD2 . LEU B 1 88  ? 151.052 154.697 126.807 1.00 26.42  ? 88  LEU B CD2 1 
ATOM   4390  N N   . PHE B 1 89  ? 152.584 153.746 122.241 1.00 25.85  ? 89  PHE B N   1 
ATOM   4391  C CA  . PHE B 1 89  ? 152.241 154.658 121.158 1.00 25.85  ? 89  PHE B CA  1 
ATOM   4392  C C   . PHE B 1 89  ? 150.919 155.338 121.493 1.00 25.85  ? 89  PHE B C   1 
ATOM   4393  O O   . PHE B 1 89  ? 149.936 154.663 121.810 1.00 25.85  ? 89  PHE B O   1 
ATOM   4394  C CB  . PHE B 1 89  ? 152.143 153.897 119.832 1.00 25.85  ? 89  PHE B CB  1 
ATOM   4395  C CG  . PHE B 1 89  ? 152.074 154.781 118.616 1.00 25.85  ? 89  PHE B CG  1 
ATOM   4396  C CD1 . PHE B 1 89  ? 150.872 155.336 118.207 1.00 25.85  ? 89  PHE B CD1 1 
ATOM   4397  C CD2 . PHE B 1 89  ? 153.209 155.044 117.872 1.00 25.85  ? 89  PHE B CD2 1 
ATOM   4398  C CE1 . PHE B 1 89  ? 150.809 156.143 117.092 1.00 25.85  ? 89  PHE B CE1 1 
ATOM   4399  C CE2 . PHE B 1 89  ? 153.150 155.850 116.754 1.00 25.85  ? 89  PHE B CE2 1 
ATOM   4400  C CZ  . PHE B 1 89  ? 151.949 156.400 116.365 1.00 25.85  ? 89  PHE B CZ  1 
ATOM   4401  N N   . VAL B 1 90  ? 150.893 156.666 121.424 1.00 26.54  ? 90  VAL B N   1 
ATOM   4402  C CA  . VAL B 1 90  ? 149.717 157.452 121.787 1.00 26.54  ? 90  VAL B CA  1 
ATOM   4403  C C   . VAL B 1 90  ? 149.115 158.048 120.521 1.00 26.54  ? 90  VAL B C   1 
ATOM   4404  O O   . VAL B 1 90  ? 149.749 158.870 119.850 1.00 26.54  ? 90  VAL B O   1 
ATOM   4405  C CB  . VAL B 1 90  ? 150.063 158.550 122.805 1.00 26.54  ? 90  VAL B CB  1 
ATOM   4406  C CG1 . VAL B 1 90  ? 148.830 159.375 123.140 1.00 26.54  ? 90  VAL B CG1 1 
ATOM   4407  C CG2 . VAL B 1 90  ? 150.648 157.939 124.064 1.00 26.54  ? 90  VAL B CG2 1 
ATOM   4408  N N   . GLU B 1 91  ? 147.885 157.649 120.207 1.00 28.91  ? 91  GLU B N   1 
ATOM   4409  C CA  . GLU B 1 91  ? 147.161 158.136 119.039 1.00 28.91  ? 91  GLU B CA  1 
ATOM   4410  C C   . GLU B 1 91  ? 146.215 159.259 119.446 1.00 28.91  ? 91  GLU B C   1 
ATOM   4411  O O   . GLU B 1 91  ? 145.430 159.105 120.386 1.00 28.91  ? 91  GLU B O   1 
ATOM   4412  C CB  . GLU B 1 91  ? 146.371 157.005 118.377 1.00 28.91  ? 91  GLU B CB  1 
ATOM   4413  C CG  . GLU B 1 91  ? 147.110 156.283 117.270 1.00 28.91  ? 91  GLU B CG  1 
ATOM   4414  C CD  . GLU B 1 91  ? 146.283 155.176 116.642 1.00 28.91  ? 91  GLU B CD  1 
ATOM   4415  O OE1 . GLU B 1 91  ? 145.248 154.798 117.225 1.00 28.91  ? 91  GLU B OE1 1 
ATOM   4416  O OE2 . GLU B 1 91  ? 146.671 154.683 115.565 1.00 28.91  ? 91  GLU B OE2 1 
ATOM   4417  N N   . ARG B 1 92  ? 146.285 160.377 118.732 1.00 29.65  ? 92  ARG B N   1 
ATOM   4418  C CA  . ARG B 1 92  ? 145.443 161.532 119.001 1.00 29.65  ? 92  ARG B CA  1 
ATOM   4419  C C   . ARG B 1 92  ? 144.179 161.490 118.149 1.00 29.65  ? 92  ARG B C   1 
ATOM   4420  O O   . ARG B 1 92  ? 144.123 160.840 117.104 1.00 29.65  ? 92  ARG B O   1 
ATOM   4421  C CB  . ARG B 1 92  ? 146.203 162.833 118.740 1.00 29.65  ? 92  ARG B CB  1 
ATOM   4422  C CG  . ARG B 1 92  ? 147.583 162.896 119.370 1.00 29.65  ? 92  ARG B CG  1 
ATOM   4423  C CD  . ARG B 1 92  ? 147.516 162.648 120.862 1.00 29.65  ? 92  ARG B CD  1 
ATOM   4424  N NE  . ARG B 1 92  ? 148.658 163.212 121.570 1.00 29.65  ? 92  ARG B NE  1 
ATOM   4425  C CZ  . ARG B 1 92  ? 148.759 163.283 122.890 1.00 29.65  ? 92  ARG B CZ  1 
ATOM   4426  N NH1 . ARG B 1 92  ? 147.807 162.821 123.681 1.00 29.65  ? 92  ARG B NH1 1 
ATOM   4427  N NH2 . ARG B 1 92  ? 149.842 163.834 123.428 1.00 29.65  ? 92  ARG B NH2 1 
ATOM   4428  N N   . SER B 1 93  ? 143.154 162.204 118.613 1.00 32.77  ? 93  SER B N   1 
ATOM   4429  C CA  . SER B 1 93  ? 141.874 162.242 117.918 1.00 32.77  ? 93  SER B CA  1 
ATOM   4430  C C   . SER B 1 93  ? 141.864 163.202 116.734 1.00 32.77  ? 93  SER B C   1 
ATOM   4431  O O   . SER B 1 93  ? 140.907 163.182 115.954 1.00 32.77  ? 93  SER B O   1 
ATOM   4432  C CB  . SER B 1 93  ? 140.757 162.614 118.896 1.00 32.77  ? 93  SER B CB  1 
ATOM   4433  O OG  . SER B 1 93  ? 140.711 164.011 119.117 1.00 32.77  ? 93  SER B OG  1 
ATOM   4434  N N   . SER B 1 94  ? 142.891 164.032 116.578 1.00 32.12  ? 94  SER B N   1 
ATOM   4435  C CA  . SER B 1 94  ? 142.995 164.940 115.445 1.00 32.12  ? 94  SER B CA  1 
ATOM   4436  C C   . SER B 1 94  ? 143.826 164.365 114.302 1.00 32.12  ? 94  SER B C   1 
ATOM   4437  O O   . SER B 1 94  ? 144.152 165.096 113.362 1.00 32.12  ? 94  SER B O   1 
ATOM   4438  C CB  . SER B 1 94  ? 143.580 166.281 115.897 1.00 32.12  ? 94  SER B CB  1 
ATOM   4439  O OG  . SER B 1 94  ? 144.864 166.118 116.471 1.00 32.12  ? 94  SER B OG  1 
ATOM   4440  N N   . ALA B 1 95  ? 144.176 163.083 114.363 1.00 31.48  ? 95  ALA B N   1 
ATOM   4441  C CA  . ALA B 1 95  ? 144.927 162.445 113.290 1.00 31.48  ? 95  ALA B CA  1 
ATOM   4442  C C   . ALA B 1 95  ? 144.089 162.354 112.018 1.00 31.48  ? 95  ALA B C   1 
ATOM   4443  O O   . ALA B 1 95  ? 142.865 162.211 112.063 1.00 31.48  ? 95  ALA B O   1 
ATOM   4444  C CB  . ALA B 1 95  ? 145.382 161.051 113.718 1.00 31.48  ? 95  ALA B CB  1 
ATOM   4445  N N   . PHE B 1 96  ? 144.765 162.439 110.873 1.00 30.63  ? 96  PHE B N   1 
ATOM   4446  C CA  . PHE B 1 96  ? 144.097 162.402 109.579 1.00 30.63  ? 96  PHE B CA  1 
ATOM   4447  C C   . PHE B 1 96  ? 145.014 161.757 108.547 1.00 30.63  ? 96  PHE B C   1 
ATOM   4448  O O   . PHE B 1 96  ? 146.223 161.637 108.750 1.00 30.63  ? 96  PHE B O   1 
ATOM   4449  C CB  . PHE B 1 96  ? 143.669 163.808 109.125 1.00 30.63  ? 96  PHE B CB  1 
ATOM   4450  C CG  . PHE B 1 96  ? 144.817 164.752 108.877 1.00 30.63  ? 96  PHE B CG  1 
ATOM   4451  C CD1 . PHE B 1 96  ? 145.350 165.504 109.909 1.00 30.63  ? 96  PHE B CD1 1 
ATOM   4452  C CD2 . PHE B 1 96  ? 145.350 164.900 107.608 1.00 30.63  ? 96  PHE B CD2 1 
ATOM   4453  C CE1 . PHE B 1 96  ? 146.398 166.374 109.684 1.00 30.63  ? 96  PHE B CE1 1 
ATOM   4454  C CE2 . PHE B 1 96  ? 146.399 165.769 107.377 1.00 30.63  ? 96  PHE B CE2 1 
ATOM   4455  C CZ  . PHE B 1 96  ? 146.923 166.508 108.417 1.00 30.63  ? 96  PHE B CZ  1 
ATOM   4456  N N   . SER B 1 97  ? 144.416 161.338 107.434 1.00 29.65  ? 97  SER B N   1 
ATOM   4457  C CA  . SER B 1 97  ? 145.126 160.709 106.327 1.00 29.65  ? 97  SER B CA  1 
ATOM   4458  C C   . SER B 1 97  ? 145.169 161.660 105.139 1.00 29.65  ? 97  SER B C   1 
ATOM   4459  O O   . SER B 1 97  ? 144.193 162.363 104.862 1.00 29.65  ? 97  SER B O   1 
ATOM   4460  C CB  . SER B 1 97  ? 144.453 159.398 105.918 1.00 29.65  ? 97  SER B CB  1 
ATOM   4461  O OG  . SER B 1 97  ? 144.652 158.391 106.891 1.00 29.65  ? 97  SER B OG  1 
ATOM   4462  N N   . ASN B 1 98  ? 146.304 161.688 104.442 1.00 28.85  ? 98  ASN B N   1 
ATOM   4463  C CA  . ASN B 1 98  ? 146.517 162.642 103.356 1.00 28.85  ? 98  ASN B CA  1 
ATOM   4464  C C   . ASN B 1 98  ? 147.221 161.986 102.171 1.00 28.85  ? 98  ASN B C   1 
ATOM   4465  O O   . ASN B 1 98  ? 148.156 162.550 101.597 1.00 28.85  ? 98  ASN B O   1 
ATOM   4466  C CB  . ASN B 1 98  ? 147.308 163.853 103.847 1.00 28.85  ? 98  ASN B CB  1 
ATOM   4467  C CG  . ASN B 1 98  ? 146.953 165.121 103.104 1.00 28.85  ? 98  ASN B CG  1 
ATOM   4468  O OD1 . ASN B 1 98  ? 145.790 165.366 102.793 1.00 28.85  ? 98  ASN B OD1 1 
ATOM   4469  N ND2 . ASN B 1 98  ? 147.957 165.938 102.818 1.00 28.85  ? 98  ASN B ND2 1 
ATOM   4470  N N   . CYS B 1 99  ? 146.786 160.794 101.784 1.00 27.52  ? 99  CYS B N   1 
ATOM   4471  C CA  . CYS B 1 99  ? 147.412 160.067 100.681 1.00 27.52  ? 99  CYS B CA  1 
ATOM   4472  C C   . CYS B 1 99  ? 146.304 159.412 99.860  1.00 27.52  ? 99  CYS B C   1 
ATOM   4473  O O   . CYS B 1 99  ? 145.132 159.793 99.944  1.00 27.52  ? 99  CYS B O   1 
ATOM   4474  C CB  . CYS B 1 99  ? 148.453 159.067 101.212 1.00 27.52  ? 99  CYS B CB  1 
ATOM   4475  S SG  . CYS B 1 99  ? 149.607 158.421 99.964  1.00 27.52  ? 99  CYS B SG  1 
ATOM   4476  N N   . TYR B 1 100 ? 146.679 158.446 99.027  1.00 23.71  ? 100 TYR B N   1 
ATOM   4477  C CA  . TYR B 1 100 ? 145.702 157.732 98.217  1.00 23.71  ? 100 TYR B CA  1 
ATOM   4478  C C   . TYR B 1 100 ? 144.719 156.986 99.118  1.00 23.71  ? 100 TYR B C   1 
ATOM   4479  O O   . TYR B 1 100 ? 145.131 156.357 100.098 1.00 23.71  ? 100 TYR B O   1 
ATOM   4480  C CB  . TYR B 1 100 ? 146.404 156.751 97.276  1.00 23.71  ? 100 TYR B CB  1 
ATOM   4481  C CG  . TYR B 1 100 ? 145.601 156.377 96.050  1.00 23.71  ? 100 TYR B CG  1 
ATOM   4482  C CD1 . TYR B 1 100 ? 145.668 157.140 94.891  1.00 23.71  ? 100 TYR B CD1 1 
ATOM   4483  C CD2 . TYR B 1 100 ? 144.777 155.261 96.050  1.00 23.71  ? 100 TYR B CD2 1 
ATOM   4484  C CE1 . TYR B 1 100 ? 144.937 156.802 93.771  1.00 23.71  ? 100 TYR B CE1 1 
ATOM   4485  C CE2 . TYR B 1 100 ? 144.042 154.915 94.936  1.00 23.71  ? 100 TYR B CE2 1 
ATOM   4486  C CZ  . TYR B 1 100 ? 144.125 155.690 93.800  1.00 23.71  ? 100 TYR B CZ  1 
ATOM   4487  O OH  . TYR B 1 100 ? 143.395 155.349 92.689  1.00 23.71  ? 100 TYR B OH  1 
ATOM   4488  N N   . PRO B 1 101 ? 143.418 157.047 98.830  1.00 22.62  ? 101 PRO B N   1 
ATOM   4489  C CA  . PRO B 1 101 ? 142.440 156.352 99.679  1.00 22.62  ? 101 PRO B CA  1 
ATOM   4490  C C   . PRO B 1 101 ? 142.654 154.844 99.673  1.00 22.62  ? 101 PRO B C   1 
ATOM   4491  O O   . PRO B 1 101 ? 142.927 154.240 98.635  1.00 22.62  ? 101 PRO B O   1 
ATOM   4492  C CB  . PRO B 1 101 ? 141.092 156.735 99.058  1.00 22.62  ? 101 PRO B CB  1 
ATOM   4493  C CG  . PRO B 1 101 ? 141.411 157.199 97.680  1.00 22.62  ? 101 PRO B CG  1 
ATOM   4494  C CD  . PRO B 1 101 ? 142.778 157.792 97.735  1.00 22.62  ? 101 PRO B CD  1 
ATOM   4495  N N   . TYR B 1 102 ? 142.506 154.236 100.848 1.00 22.99  ? 102 TYR B N   1 
ATOM   4496  C CA  . TYR B 1 102 ? 142.796 152.821 101.021 1.00 22.99  ? 102 TYR B CA  1 
ATOM   4497  C C   . TYR B 1 102 ? 141.905 152.247 102.114 1.00 22.99  ? 102 TYR B C   1 
ATOM   4498  O O   . TYR B 1 102 ? 141.237 152.975 102.850 1.00 22.99  ? 102 TYR B O   1 
ATOM   4499  C CB  . TYR B 1 102 ? 144.274 152.591 101.357 1.00 22.99  ? 102 TYR B CB  1 
ATOM   4500  C CG  . TYR B 1 102 ? 144.655 153.019 102.755 1.00 22.99  ? 102 TYR B CG  1 
ATOM   4501  C CD1 . TYR B 1 102 ? 145.082 154.314 103.011 1.00 22.99  ? 102 TYR B CD1 1 
ATOM   4502  C CD2 . TYR B 1 102 ? 144.589 152.131 103.821 1.00 22.99  ? 102 TYR B CD2 1 
ATOM   4503  C CE1 . TYR B 1 102 ? 145.426 154.712 104.282 1.00 22.99  ? 102 TYR B CE1 1 
ATOM   4504  C CE2 . TYR B 1 102 ? 144.929 152.521 105.097 1.00 22.99  ? 102 TYR B CE2 1 
ATOM   4505  C CZ  . TYR B 1 102 ? 145.350 153.813 105.323 1.00 22.99  ? 102 TYR B CZ  1 
ATOM   4506  O OH  . TYR B 1 102 ? 145.695 154.209 106.592 1.00 22.99  ? 102 TYR B OH  1 
ATOM   4507  N N   . ASP B 1 103 ? 141.905 150.918 102.210 1.00 24.40  ? 103 ASP B N   1 
ATOM   4508  C CA  . ASP B 1 103 ? 141.248 150.218 103.304 1.00 24.40  ? 103 ASP B CA  1 
ATOM   4509  C C   . ASP B 1 103 ? 142.055 148.973 103.645 1.00 24.40  ? 103 ASP B C   1 
ATOM   4510  O O   . ASP B 1 103 ? 142.807 148.452 102.819 1.00 24.40  ? 103 ASP B O   1 
ATOM   4511  C CB  . ASP B 1 103 ? 139.803 149.840 102.960 1.00 24.40  ? 103 ASP B CB  1 
ATOM   4512  C CG  . ASP B 1 103 ? 139.711 148.906 101.773 1.00 24.40  ? 103 ASP B CG  1 
ATOM   4513  O OD1 . ASP B 1 103 ? 139.710 149.398 100.625 1.00 24.40  ? 103 ASP B OD1 1 
ATOM   4514  O OD2 . ASP B 1 103 ? 139.641 147.679 101.986 1.00 24.40  ? 103 ASP B OD2 1 
ATOM   4515  N N   . VAL B 1 104 ? 141.896 148.505 104.878 1.00 23.41  ? 104 VAL B N   1 
ATOM   4516  C CA  . VAL B 1 104 ? 142.602 147.319 105.358 1.00 23.41  ? 104 VAL B CA  1 
ATOM   4517  C C   . VAL B 1 104 ? 141.590 146.287 105.841 1.00 23.41  ? 104 VAL B C   1 
ATOM   4518  O O   . VAL B 1 104 ? 140.926 146.511 106.862 1.00 23.41  ? 104 VAL B O   1 
ATOM   4519  C CB  . VAL B 1 104 ? 143.592 147.668 106.483 1.00 23.41  ? 104 VAL B CB  1 
ATOM   4520  C CG1 . VAL B 1 104 ? 144.409 146.445 106.873 1.00 23.41  ? 104 VAL B CG1 1 
ATOM   4521  C CG2 . VAL B 1 104 ? 144.500 148.814 106.076 1.00 23.41  ? 104 VAL B CG2 1 
ATOM   4522  N N   . PRO B 1 105 ? 141.425 145.161 105.151 1.00 24.37  ? 105 PRO B N   1 
ATOM   4523  C CA  . PRO B 1 105 ? 140.633 144.066 105.725 1.00 24.37  ? 105 PRO B CA  1 
ATOM   4524  C C   . PRO B 1 105 ? 141.269 143.588 107.024 1.00 24.37  ? 105 PRO B C   1 
ATOM   4525  O O   . PRO B 1 105 ? 142.473 143.331 107.086 1.00 24.37  ? 105 PRO B O   1 
ATOM   4526  C CB  . PRO B 1 105 ? 140.669 142.985 104.637 1.00 24.37  ? 105 PRO B CB  1 
ATOM   4527  C CG  . PRO B 1 105 ? 141.095 143.688 103.392 1.00 24.37  ? 105 PRO B CG  1 
ATOM   4528  C CD  . PRO B 1 105 ? 141.946 144.837 103.814 1.00 24.37  ? 105 PRO B CD  1 
ATOM   4529  N N   . ASP B 1 106 ? 140.448 143.476 108.064 1.00 26.51  ? 106 ASP B N   1 
ATOM   4530  C CA  . ASP B 1 106 ? 140.916 143.215 109.426 1.00 26.51  ? 106 ASP B CA  1 
ATOM   4531  C C   . ASP B 1 106 ? 141.958 144.254 109.849 1.00 26.51  ? 106 ASP B C   1 
ATOM   4532  O O   . ASP B 1 106 ? 143.114 143.946 110.141 1.00 26.51  ? 106 ASP B O   1 
ATOM   4533  C CB  . ASP B 1 106 ? 141.460 141.791 109.567 1.00 26.51  ? 106 ASP B CB  1 
ATOM   4534  C CG  . ASP B 1 106 ? 141.181 141.194 110.937 1.00 26.51  ? 106 ASP B CG  1 
ATOM   4535  O OD1 . ASP B 1 106 ? 140.926 141.966 111.886 1.00 26.51  ? 106 ASP B OD1 1 
ATOM   4536  O OD2 . ASP B 1 106 ? 141.221 139.953 111.066 1.00 26.51  ? 106 ASP B OD2 1 
ATOM   4537  N N   . TYR B 1 107 ? 141.508 145.509 109.874 1.00 24.20  ? 107 TYR B N   1 
ATOM   4538  C CA  . TYR B 1 107 ? 142.359 146.622 110.285 1.00 24.20  ? 107 TYR B CA  1 
ATOM   4539  C C   . TYR B 1 107 ? 142.843 146.456 111.722 1.00 24.20  ? 107 TYR B C   1 
ATOM   4540  O O   . TYR B 1 107 ? 144.015 146.716 112.030 1.00 24.20  ? 107 TYR B O   1 
ATOM   4541  C CB  . TYR B 1 107 ? 141.579 147.928 110.117 1.00 24.20  ? 107 TYR B CB  1 
ATOM   4542  C CG  . TYR B 1 107 ? 142.304 149.189 110.522 1.00 24.20  ? 107 TYR B CG  1 
ATOM   4543  C CD1 . TYR B 1 107 ? 142.267 149.648 111.832 1.00 24.20  ? 107 TYR B CD1 1 
ATOM   4544  C CD2 . TYR B 1 107 ? 142.998 149.940 109.586 1.00 24.20  ? 107 TYR B CD2 1 
ATOM   4545  C CE1 . TYR B 1 107 ? 142.918 150.804 112.200 1.00 24.20  ? 107 TYR B CE1 1 
ATOM   4546  C CE2 . TYR B 1 107 ? 143.650 151.099 109.944 1.00 24.20  ? 107 TYR B CE2 1 
ATOM   4547  C CZ  . TYR B 1 107 ? 143.609 151.526 111.252 1.00 24.20  ? 107 TYR B CZ  1 
ATOM   4548  O OH  . TYR B 1 107 ? 144.259 152.682 111.609 1.00 24.20  ? 107 TYR B OH  1 
ATOM   4549  N N   . ALA B 1 108 ? 141.950 146.022 112.615 1.00 24.47  ? 108 ALA B N   1 
ATOM   4550  C CA  . ALA B 1 108 ? 142.283 145.936 114.033 1.00 24.47  ? 108 ALA B CA  1 
ATOM   4551  C C   . ALA B 1 108 ? 143.417 144.952 114.288 1.00 24.47  ? 108 ALA B C   1 
ATOM   4552  O O   . ALA B 1 108 ? 144.299 145.216 115.111 1.00 24.47  ? 108 ALA B O   1 
ATOM   4553  C CB  . ALA B 1 108 ? 141.042 145.549 114.836 1.00 24.47  ? 108 ALA B CB  1 
ATOM   4554  N N   . SER B 1 109 ? 143.413 143.811 113.595 1.00 24.99  ? 109 SER B N   1 
ATOM   4555  C CA  . SER B 1 109 ? 144.453 142.809 113.809 1.00 24.99  ? 109 SER B CA  1 
ATOM   4556  C C   . SER B 1 109 ? 145.828 143.324 113.395 1.00 24.99  ? 109 SER B C   1 
ATOM   4557  O O   . SER B 1 109 ? 146.811 143.134 114.120 1.00 24.99  ? 109 SER B O   1 
ATOM   4558  C CB  . SER B 1 109 ? 144.110 141.528 113.050 1.00 24.99  ? 109 SER B CB  1 
ATOM   4559  O OG  . SER B 1 109 ? 143.178 140.748 113.773 1.00 24.99  ? 109 SER B OG  1 
ATOM   4560  N N   . LEU B 1 110 ? 145.922 143.972 112.231 1.00 23.48  ? 110 LEU B N   1 
ATOM   4561  C CA  . LEU B 1 110 ? 147.204 144.521 111.799 1.00 23.48  ? 110 LEU B CA  1 
ATOM   4562  C C   . LEU B 1 110 ? 147.671 145.633 112.731 1.00 23.48  ? 110 LEU B C   1 
ATOM   4563  O O   . LEU B 1 110 ? 148.860 145.710 113.068 1.00 23.48  ? 110 LEU B O   1 
ATOM   4564  C CB  . LEU B 1 110 ? 147.107 145.029 110.359 1.00 23.48  ? 110 LEU B CB  1 
ATOM   4565  C CG  . LEU B 1 110 ? 148.399 145.570 109.735 1.00 23.48  ? 110 LEU B CG  1 
ATOM   4566  C CD1 . LEU B 1 110 ? 149.475 144.496 109.660 1.00 23.48  ? 110 LEU B CD1 1 
ATOM   4567  C CD2 . LEU B 1 110 ? 148.140 146.165 108.361 1.00 23.48  ? 110 LEU B CD2 1 
ATOM   4568  N N   . ARG B 1 111 ? 146.749 146.501 113.158 1.00 24.34  ? 111 ARG B N   1 
ATOM   4569  C CA  . ARG B 1 111 ? 147.104 147.557 114.102 1.00 24.34  ? 111 ARG B CA  1 
ATOM   4570  C C   . ARG B 1 111 ? 147.648 146.969 115.400 1.00 24.34  ? 111 ARG B C   1 
ATOM   4571  O O   . ARG B 1 111 ? 148.690 147.405 115.904 1.00 24.34  ? 111 ARG B O   1 
ATOM   4572  C CB  . ARG B 1 111 ? 145.884 148.444 114.368 1.00 24.34  ? 111 ARG B CB  1 
ATOM   4573  C CG  . ARG B 1 111 ? 146.071 149.538 115.412 1.00 24.34  ? 111 ARG B CG  1 
ATOM   4574  C CD  . ARG B 1 111 ? 144.772 150.318 115.590 1.00 24.34  ? 111 ARG B CD  1 
ATOM   4575  N NE  . ARG B 1 111 ? 144.841 151.341 116.627 1.00 24.34  ? 111 ARG B NE  1 
ATOM   4576  C CZ  . ARG B 1 111 ? 144.520 151.143 117.898 1.00 24.34  ? 111 ARG B CZ  1 
ATOM   4577  N NH1 . ARG B 1 111 ? 144.135 149.958 118.338 1.00 24.34  ? 111 ARG B NH1 1 
ATOM   4578  N NH2 . ARG B 1 111 ? 144.589 152.161 118.750 1.00 24.34  ? 111 ARG B NH2 1 
ATOM   4579  N N   . SER B 1 112 ? 146.968 145.954 115.937 1.00 25.79  ? 112 SER B N   1 
ATOM   4580  C CA  . SER B 1 112 ? 147.400 145.333 117.185 1.00 25.79  ? 112 SER B CA  1 
ATOM   4581  C C   . SER B 1 112 ? 148.748 144.639 117.027 1.00 25.79  ? 112 SER B C   1 
ATOM   4582  O O   . SER B 1 112 ? 149.600 144.721 117.918 1.00 25.79  ? 112 SER B O   1 
ATOM   4583  C CB  . SER B 1 112 ? 146.336 144.348 117.669 1.00 25.79  ? 112 SER B CB  1 
ATOM   4584  O OG  . SER B 1 112 ? 146.882 143.399 118.564 1.00 25.79  ? 112 SER B OG  1 
ATOM   4585  N N   . LEU B 1 113 ? 148.960 143.959 115.899 1.00 25.73  ? 113 LEU B N   1 
ATOM   4586  C CA  . LEU B 1 113 ? 150.228 143.276 115.661 1.00 25.73  ? 113 LEU B CA  1 
ATOM   4587  C C   . LEU B 1 113 ? 151.385 144.269 115.600 1.00 25.73  ? 113 LEU B C   1 
ATOM   4588  O O   . LEU B 1 113 ? 152.424 144.076 116.249 1.00 25.73  ? 113 LEU B O   1 
ATOM   4589  C CB  . LEU B 1 113 ? 150.116 142.449 114.375 1.00 25.73  ? 113 LEU B CB  1 
ATOM   4590  C CG  . LEU B 1 113 ? 151.249 141.689 113.680 1.00 25.73  ? 113 LEU B CG  1 
ATOM   4591  C CD1 . LEU B 1 113 ? 150.630 140.764 112.653 1.00 25.73  ? 113 LEU B CD1 1 
ATOM   4592  C CD2 . LEU B 1 113 ? 152.243 142.597 112.988 1.00 25.73  ? 113 LEU B CD2 1 
ATOM   4593  N N   . ILE B 1 114 ? 151.218 145.351 114.832 1.00 25.46  ? 114 ILE B N   1 
ATOM   4594  C CA  . ILE B 1 114 ? 152.274 146.357 114.734 1.00 25.46  ? 114 ILE B CA  1 
ATOM   4595  C C   . ILE B 1 114 ? 152.528 147.005 116.089 1.00 25.46  ? 114 ILE B C   1 
ATOM   4596  O O   . ILE B 1 114 ? 153.681 147.210 116.486 1.00 25.46  ? 114 ILE B O   1 
ATOM   4597  C CB  . ILE B 1 114 ? 151.926 147.409 113.665 1.00 25.46  ? 114 ILE B CB  1 
ATOM   4598  C CG1 . ILE B 1 114 ? 151.828 146.762 112.287 1.00 25.46  ? 114 ILE B CG1 1 
ATOM   4599  C CG2 . ILE B 1 114 ? 152.980 148.501 113.640 1.00 25.46  ? 114 ILE B CG2 1 
ATOM   4600  C CD1 . ILE B 1 114 ? 153.046 145.972 111.908 1.00 25.46  ? 114 ILE B CD1 1 
ATOM   4601  N N   . ALA B 1 115 ? 151.460 147.338 116.821 1.00 25.46  ? 115 ALA B N   1 
ATOM   4602  C CA  . ALA B 1 115 ? 151.629 147.978 118.121 1.00 25.46  ? 115 ALA B CA  1 
ATOM   4603  C C   . ALA B 1 115 ? 152.353 147.064 119.098 1.00 25.46  ? 115 ALA B C   1 
ATOM   4604  O O   . ALA B 1 115 ? 153.190 147.523 119.884 1.00 25.46  ? 115 ALA B O   1 
ATOM   4605  C CB  . ALA B 1 115 ? 150.272 148.395 118.684 1.00 25.46  ? 115 ALA B CB  1 
ATOM   4606  N N   . SER B 1 116 ? 152.045 145.766 119.066 1.00 27.57  ? 116 SER B N   1 
ATOM   4607  C CA  . SER B 1 116 ? 152.701 144.824 119.964 1.00 27.57  ? 116 SER B CA  1 
ATOM   4608  C C   . SER B 1 116 ? 154.170 144.643 119.607 1.00 27.57  ? 116 SER B C   1 
ATOM   4609  O O   . SER B 1 116 ? 155.008 144.459 120.495 1.00 27.57  ? 116 SER B O   1 
ATOM   4610  C CB  . SER B 1 116 ? 151.974 143.483 119.937 1.00 27.57  ? 116 SER B CB  1 
ATOM   4611  O OG  . SER B 1 116 ? 152.129 142.800 121.164 1.00 27.57  ? 116 SER B OG  1 
ATOM   4612  N N   . SER B 1 117 ? 154.502 144.686 118.313 1.00 28.02  ? 117 SER B N   1 
ATOM   4613  C CA  . SER B 1 117 ? 155.899 144.526 117.915 1.00 28.02  ? 117 SER B CA  1 
ATOM   4614  C C   . SER B 1 117 ? 156.781 145.626 118.501 1.00 28.02  ? 117 SER B C   1 
ATOM   4615  O O   . SER B 1 117 ? 157.875 145.349 119.004 1.00 28.02  ? 117 SER B O   1 
ATOM   4616  C CB  . SER B 1 117 ? 156.013 144.500 116.393 1.00 28.02  ? 117 SER B CB  1 
ATOM   4617  O OG  . SER B 1 117 ? 157.361 144.350 115.992 1.00 28.02  ? 117 SER B OG  1 
ATOM   4618  N N   . GLY B 1 118 ? 156.332 146.876 118.439 1.00 26.98  ? 118 GLY B N   1 
ATOM   4619  C CA  . GLY B 1 118 ? 157.021 147.969 119.096 1.00 26.98  ? 118 GLY B CA  1 
ATOM   4620  C C   . GLY B 1 118 ? 158.069 148.702 118.287 1.00 26.98  ? 118 GLY B C   1 
ATOM   4621  O O   . GLY B 1 118 ? 158.796 149.522 118.858 1.00 26.98  ? 118 GLY B O   1 
ATOM   4622  N N   . THR B 1 119 ? 158.171 148.449 116.984 1.00 29.29  ? 119 THR B N   1 
ATOM   4623  C CA  . THR B 1 119 ? 159.190 149.098 116.171 1.00 29.29  ? 119 THR B CA  1 
ATOM   4624  C C   . THR B 1 119 ? 158.694 149.237 114.738 1.00 29.29  ? 119 THR B C   1 
ATOM   4625  O O   . THR B 1 119 ? 157.777 148.535 114.306 1.00 29.29  ? 119 THR B O   1 
ATOM   4626  C CB  . THR B 1 119 ? 160.516 148.321 116.204 1.00 29.29  ? 119 THR B CB  1 
ATOM   4627  O OG1 . THR B 1 119 ? 161.514 149.037 115.470 1.00 29.29  ? 119 THR B OG1 1 
ATOM   4628  C CG2 . THR B 1 119 ? 160.347 146.937 115.600 1.00 29.29  ? 119 THR B CG2 1 
ATOM   4629  N N   . LEU B 1 120 ? 159.314 150.164 114.004 1.00 28.15  ? 120 LEU B N   1 
ATOM   4630  C CA  . LEU B 1 120 ? 159.043 150.370 112.586 1.00 28.15  ? 120 LEU B CA  1 
ATOM   4631  C C   . LEU B 1 120 ? 160.314 150.243 111.749 1.00 28.15  ? 120 LEU B C   1 
ATOM   4632  O O   . LEU B 1 120 ? 160.446 150.890 110.710 1.00 28.15  ? 120 LEU B O   1 
ATOM   4633  C CB  . LEU B 1 120 ? 158.387 151.731 112.345 1.00 28.15  ? 120 LEU B CB  1 
ATOM   4634  C CG  . LEU B 1 120 ? 156.923 151.909 112.755 1.00 28.15  ? 120 LEU B CG  1 
ATOM   4635  C CD1 . LEU B 1 120 ? 156.400 153.263 112.306 1.00 28.15  ? 120 LEU B CD1 1 
ATOM   4636  C CD2 . LEU B 1 120 ? 156.061 150.791 112.199 1.00 28.15  ? 120 LEU B CD2 1 
ATOM   4637  N N   . ASP B 1 121 ? 161.256 149.410 112.187 1.00 30.13  ? 121 ASP B N   1 
ATOM   4638  C CA  . ASP B 1 121 ? 162.517 149.244 111.472 1.00 30.13  ? 121 ASP B CA  1 
ATOM   4639  C C   . ASP B 1 121 ? 162.282 148.529 110.144 1.00 30.13  ? 121 ASP B C   1 
ATOM   4640  O O   . ASP B 1 121 ? 161.732 147.425 110.114 1.00 30.13  ? 121 ASP B O   1 
ATOM   4641  C CB  . ASP B 1 121 ? 163.510 148.470 112.332 1.00 30.13  ? 121 ASP B CB  1 
ATOM   4642  C CG  . ASP B 1 121 ? 164.905 148.456 111.742 1.00 30.13  ? 121 ASP B CG  1 
ATOM   4643  O OD1 . ASP B 1 121 ? 165.525 149.536 111.647 1.00 30.13  ? 121 ASP B OD1 1 
ATOM   4644  O OD2 . ASP B 1 121 ? 165.383 147.363 111.373 1.00 30.13  ? 121 ASP B OD2 1 
ATOM   4645  N N   . PHE B 1 122 ? 162.711 149.155 109.052 1.00 24.13  ? 122 PHE B N   1 
ATOM   4646  C CA  . PHE B 1 122 ? 162.443 148.691 107.698 1.00 24.13  ? 122 PHE B CA  1 
ATOM   4647  C C   . PHE B 1 122 ? 163.757 148.430 106.975 1.00 24.13  ? 122 PHE B C   1 
ATOM   4648  O O   . PHE B 1 122 ? 164.698 149.222 107.077 1.00 24.13  ? 122 PHE B O   1 
ATOM   4649  C CB  . PHE B 1 122 ? 161.603 149.728 106.934 1.00 24.13  ? 122 PHE B CB  1 
ATOM   4650  C CG  . PHE B 1 122 ? 161.149 149.280 105.572 1.00 24.13  ? 122 PHE B CG  1 
ATOM   4651  C CD1 . PHE B 1 122 ? 159.986 148.546 105.419 1.00 24.13  ? 122 PHE B CD1 1 
ATOM   4652  C CD2 . PHE B 1 122 ? 161.870 149.621 104.440 1.00 24.13  ? 122 PHE B CD2 1 
ATOM   4653  C CE1 . PHE B 1 122 ? 159.563 148.142 104.169 1.00 24.13  ? 122 PHE B CE1 1 
ATOM   4654  C CE2 . PHE B 1 122 ? 161.450 149.223 103.188 1.00 24.13  ? 122 PHE B CE2 1 
ATOM   4655  C CZ  . PHE B 1 122 ? 160.295 148.486 103.052 1.00 24.13  ? 122 PHE B CZ  1 
ATOM   4656  N N   . ILE B 1 123 ? 163.821 147.315 106.250 1.00 24.99  ? 123 ILE B N   1 
ATOM   4657  C CA  . ILE B 1 123 ? 164.993 146.937 105.468 1.00 24.99  ? 123 ILE B CA  1 
ATOM   4658  C C   . ILE B 1 123 ? 164.584 146.884 104.004 1.00 24.99  ? 123 ILE B C   1 
ATOM   4659  O O   . ILE B 1 123 ? 163.638 146.172 103.645 1.00 24.99  ? 123 ILE B O   1 
ATOM   4660  C CB  . ILE B 1 123 ? 165.575 145.587 105.918 1.00 24.99  ? 123 ILE B CB  1 
ATOM   4661  C CG1 . ILE B 1 123 ? 165.827 145.576 107.428 1.00 24.99  ? 123 ILE B CG1 1 
ATOM   4662  C CG2 . ILE B 1 123 ? 166.846 145.273 105.146 1.00 24.99  ? 123 ILE B CG2 1 
ATOM   4663  C CD1 . ILE B 1 123 ? 167.070 146.314 107.846 1.00 24.99  ? 123 ILE B CD1 1 
ATOM   4664  N N   . THR B 1 124 ? 165.300 147.628 103.164 1.00 27.05  ? 124 THR B N   1 
ATOM   4665  C CA  . THR B 1 124 ? 165.031 147.651 101.733 1.00 27.05  ? 124 THR B CA  1 
ATOM   4666  C C   . THR B 1 124 ? 165.665 146.449 101.045 1.00 27.05  ? 124 THR B C   1 
ATOM   4667  O O   . THR B 1 124 ? 166.814 146.094 101.317 1.00 27.05  ? 124 THR B O   1 
ATOM   4668  C CB  . THR B 1 124 ? 165.563 148.945 101.114 1.00 27.05  ? 124 THR B CB  1 
ATOM   4669  O OG1 . THR B 1 124 ? 165.017 150.071 101.810 1.00 27.05  ? 124 THR B OG1 1 
ATOM   4670  C CG2 . THR B 1 124 ? 165.189 149.039 99.642  1.00 27.05  ? 124 THR B CG2 1 
ATOM   4671  N N   . GLU B 1 125 ? 164.910 145.827 100.145 1.00 28.10  ? 125 GLU B N   1 
ATOM   4672  C CA  . GLU B 1 125 ? 165.382 144.691 99.370  1.00 28.10  ? 125 GLU B CA  1 
ATOM   4673  C C   . GLU B 1 125 ? 165.351 145.032 97.887  1.00 28.10  ? 125 GLU B C   1 
ATOM   4674  O O   . GLU B 1 125 ? 164.618 145.921 97.448  1.00 28.10  ? 125 GLU B O   1 
ATOM   4675  C CB  . GLU B 1 125 ? 164.543 143.441 99.650  1.00 28.10  ? 125 GLU B CB  1 
ATOM   4676  C CG  . GLU B 1 125 ? 164.931 142.731 100.930 1.00 28.10  ? 125 GLU B CG  1 
ATOM   4677  C CD  . GLU B 1 125 ? 164.043 141.548 101.243 1.00 28.10  ? 125 GLU B CD  1 
ATOM   4678  O OE1 . GLU B 1 125 ? 162.835 141.612 100.941 1.00 28.10  ? 125 GLU B OE1 1 
ATOM   4679  O OE2 . GLU B 1 125 ? 164.554 140.553 101.794 1.00 28.10  ? 125 GLU B OE2 1 
ATOM   4680  N N   . SER B 1 126 ? 166.165 144.320 97.113  1.00 29.78  ? 126 SER B N   1 
ATOM   4681  C CA  . SER B 1 126 ? 166.329 144.596 95.685  1.00 29.78  ? 126 SER B CA  1 
ATOM   4682  C C   . SER B 1 126 ? 165.447 143.636 94.893  1.00 29.78  ? 126 SER B C   1 
ATOM   4683  O O   . SER B 1 126 ? 165.896 142.592 94.423  1.00 29.78  ? 126 SER B O   1 
ATOM   4684  C CB  . SER B 1 126 ? 167.794 144.487 95.276  1.00 29.78  ? 126 SER B CB  1 
ATOM   4685  O OG  . SER B 1 126 ? 168.300 143.187 95.514  1.00 29.78  ? 126 SER B OG  1 
ATOM   4686  N N   . PHE B 1 127 ? 164.178 144.001 94.746  1.00 28.55  ? 127 PHE B N   1 
ATOM   4687  C CA  . PHE B 1 127 ? 163.275 143.289 93.857  1.00 28.55  ? 127 PHE B CA  1 
ATOM   4688  C C   . PHE B 1 127 ? 163.522 143.706 92.414  1.00 28.55  ? 127 PHE B C   1 
ATOM   4689  O O   . PHE B 1 127 ? 163.955 144.827 92.135  1.00 28.55  ? 127 PHE B O   1 
ATOM   4690  C CB  . PHE B 1 127 ? 161.819 143.566 94.232  1.00 28.55  ? 127 PHE B CB  1 
ATOM   4691  C CG  . PHE B 1 127 ? 161.392 142.939 95.525  1.00 28.55  ? 127 PHE B CG  1 
ATOM   4692  C CD1 . PHE B 1 127 ? 160.915 141.641 95.557  1.00 28.55  ? 127 PHE B CD1 1 
ATOM   4693  C CD2 . PHE B 1 127 ? 161.461 143.650 96.708  1.00 28.55  ? 127 PHE B CD2 1 
ATOM   4694  C CE1 . PHE B 1 127 ? 160.518 141.065 96.745  1.00 28.55  ? 127 PHE B CE1 1 
ATOM   4695  C CE2 . PHE B 1 127 ? 161.064 143.080 97.899  1.00 28.55  ? 127 PHE B CE2 1 
ATOM   4696  C CZ  . PHE B 1 127 ? 160.594 141.785 97.918  1.00 28.55  ? 127 PHE B CZ  1 
ATOM   4697  N N   . THR B 1 128 ? 163.242 142.792 91.490  1.00 30.62  ? 128 THR B N   1 
ATOM   4698  C CA  . THR B 1 128 ? 163.387 143.051 90.063  1.00 30.62  ? 128 THR B CA  1 
ATOM   4699  C C   . THR B 1 128 ? 162.036 142.863 89.391  1.00 30.62  ? 128 THR B C   1 
ATOM   4700  O O   . THR B 1 128 ? 161.485 141.758 89.397  1.00 30.62  ? 128 THR B O   1 
ATOM   4701  C CB  . THR B 1 128 ? 164.430 142.127 89.431  1.00 30.62  ? 128 THR B CB  1 
ATOM   4702  O OG1 . THR B 1 128 ? 165.615 142.120 90.235  1.00 30.62  ? 128 THR B OG1 1 
ATOM   4703  C CG2 . THR B 1 128 ? 164.782 142.610 88.035  1.00 30.62  ? 128 THR B CG2 1 
ATOM   4704  N N   . TRP B 1 129 ? 161.511 143.936 88.811  1.00 28.04  ? 129 TRP B N   1 
ATOM   4705  C CA  . TRP B 1 129 ? 160.228 143.922 88.117  1.00 28.04  ? 129 TRP B CA  1 
ATOM   4706  C C   . TRP B 1 129 ? 160.503 144.199 86.642  1.00 28.04  ? 129 TRP B C   1 
ATOM   4707  O O   . TRP B 1 129 ? 160.650 145.354 86.234  1.00 28.04  ? 129 TRP B O   1 
ATOM   4708  C CB  . TRP B 1 129 ? 159.272 144.945 88.723  1.00 28.04  ? 129 TRP B CB  1 
ATOM   4709  C CG  . TRP B 1 129 ? 159.237 144.924 90.225  1.00 28.04  ? 129 TRP B CG  1 
ATOM   4710  C CD1 . TRP B 1 129 ? 159.800 145.834 91.070  1.00 28.04  ? 129 TRP B CD1 1 
ATOM   4711  C CD2 . TRP B 1 129 ? 158.606 143.943 91.056  1.00 28.04  ? 129 TRP B CD2 1 
ATOM   4712  N NE1 . TRP B 1 129 ? 159.559 145.482 92.374  1.00 28.04  ? 129 TRP B NE1 1 
ATOM   4713  C CE2 . TRP B 1 129 ? 158.827 144.325 92.393  1.00 28.04  ? 129 TRP B CE2 1 
ATOM   4714  C CE3 . TRP B 1 129 ? 157.875 142.780 90.800  1.00 28.04  ? 129 TRP B CE3 1 
ATOM   4715  C CZ2 . TRP B 1 129 ? 158.344 143.585 93.470  1.00 28.04  ? 129 TRP B CZ2 1 
ATOM   4716  C CZ3 . TRP B 1 129 ? 157.395 142.049 91.870  1.00 28.04  ? 129 TRP B CZ3 1 
ATOM   4717  C CH2 . TRP B 1 129 ? 157.632 142.454 93.187  1.00 28.04  ? 129 TRP B CH2 1 
ATOM   4718  N N   . ALA B 1 130 ? 160.563 143.137 85.844  1.00 31.33  ? 130 ALA B N   1 
ATOM   4719  C CA  . ALA B 1 130 ? 160.992 143.229 84.455  1.00 31.33  ? 130 ALA B CA  1 
ATOM   4720  C C   . ALA B 1 130 ? 159.805 143.482 83.534  1.00 31.33  ? 130 ALA B C   1 
ATOM   4721  O O   . ALA B 1 130 ? 158.808 142.757 83.581  1.00 31.33  ? 130 ALA B O   1 
ATOM   4722  C CB  . ALA B 1 130 ? 161.717 141.950 84.037  1.00 31.33  ? 130 ALA B CB  1 
ATOM   4723  N N   . GLY B 1 131 ? 159.924 144.505 82.692  1.00 32.03  ? 131 GLY B N   1 
ATOM   4724  C CA  . GLY B 1 131 ? 158.914 144.805 81.700  1.00 32.03  ? 131 GLY B CA  1 
ATOM   4725  C C   . GLY B 1 131 ? 157.801 145.726 82.144  1.00 32.03  ? 131 GLY B C   1 
ATOM   4726  O O   . GLY B 1 131 ? 156.797 145.839 81.433  1.00 32.03  ? 131 GLY B O   1 
ATOM   4727  N N   . VAL B 1 132 ? 157.937 146.384 83.295  1.00 30.44  ? 132 VAL B N   1 
ATOM   4728  C CA  . VAL B 1 132 ? 156.933 147.315 83.788  1.00 30.44  ? 132 VAL B CA  1 
ATOM   4729  C C   . VAL B 1 132 ? 157.628 148.592 84.239  1.00 30.44  ? 132 VAL B C   1 
ATOM   4730  O O   . VAL B 1 132 ? 158.840 148.624 84.460  1.00 30.44  ? 132 VAL B O   1 
ATOM   4731  C CB  . VAL B 1 132 ? 156.096 146.724 84.945  1.00 30.44  ? 132 VAL B CB  1 
ATOM   4732  C CG1 . VAL B 1 132 ? 155.231 145.573 84.452  1.00 30.44  ? 132 VAL B CG1 1 
ATOM   4733  C CG2 . VAL B 1 132 ? 156.999 146.274 86.079  1.00 30.44  ? 132 VAL B CG2 1 
ATOM   4734  N N   . SER B 1 133 ? 156.842 149.654 84.369  1.00 30.11  ? 133 SER B N   1 
ATOM   4735  C CA  . SER B 1 133 ? 157.324 150.907 84.930  1.00 30.11  ? 133 SER B CA  1 
ATOM   4736  C C   . SER B 1 133 ? 156.997 150.969 86.417  1.00 30.11  ? 133 SER B C   1 
ATOM   4737  O O   . SER B 1 133 ? 155.979 150.441 86.869  1.00 30.11  ? 133 SER B O   1 
ATOM   4738  C CB  . SER B 1 133 ? 156.716 152.109 84.204  1.00 30.11  ? 133 SER B CB  1 
ATOM   4739  O OG  . SER B 1 133 ? 155.310 152.012 84.149  1.00 30.11  ? 133 SER B OG  1 
ATOM   4740  N N   . GLN B 1 134 ? 157.875 151.616 87.175  1.00 28.77  ? 134 GLN B N   1 
ATOM   4741  C CA  . GLN B 1 134 ? 157.774 151.679 88.625  1.00 28.77  ? 134 GLN B CA  1 
ATOM   4742  C C   . GLN B 1 134 ? 157.530 153.109 89.091  1.00 28.77  ? 134 GLN B C   1 
ATOM   4743  O O   . GLN B 1 134 ? 157.571 154.062 88.310  1.00 28.77  ? 134 GLN B O   1 
ATOM   4744  C CB  . GLN B 1 134 ? 159.042 151.120 89.280  1.00 28.77  ? 134 GLN B CB  1 
ATOM   4745  C CG  . GLN B 1 134 ? 159.615 149.895 88.595  1.00 28.77  ? 134 GLN B CG  1 
ATOM   4746  C CD  . GLN B 1 134 ? 160.740 149.259 89.386  1.00 28.77  ? 134 GLN B CD  1 
ATOM   4747  O OE1 . GLN B 1 134 ? 160.950 149.580 90.555  1.00 28.77  ? 134 GLN B OE1 1 
ATOM   4748  N NE2 . GLN B 1 134 ? 161.478 148.360 88.748  1.00 28.77  ? 134 GLN B NE2 1 
ATOM   4749  N N   . ASN B 1 135 ? 157.262 153.238 90.393  1.00 28.86  ? 135 ASN B N   1 
ATOM   4750  C CA  . ASN B 1 135 ? 157.123 154.531 91.067  1.00 28.86  ? 135 ASN B CA  1 
ATOM   4751  C C   . ASN B 1 135 ? 155.950 155.341 90.511  1.00 28.86  ? 135 ASN B C   1 
ATOM   4752  O O   . ASN B 1 135 ? 156.091 156.509 90.146  1.00 28.86  ? 135 ASN B O   1 
ATOM   4753  C CB  . ASN B 1 135 ? 158.425 155.337 90.995  1.00 28.86  ? 135 ASN B CB  1 
ATOM   4754  C CG  . ASN B 1 135 ? 159.642 154.521 91.380  1.00 28.86  ? 135 ASN B CG  1 
ATOM   4755  O OD1 . ASN B 1 135 ? 159.670 153.882 92.431  1.00 28.86  ? 135 ASN B OD1 1 
ATOM   4756  N ND2 . ASN B 1 135 ? 160.656 154.539 90.530  1.00 28.86  ? 135 ASN B ND2 1 
ATOM   4757  N N   . GLY B 1 136 ? 154.781 154.711 90.451  1.00 28.66  ? 136 GLY B N   1 
ATOM   4758  C CA  . GLY B 1 136 ? 153.577 155.438 90.098  1.00 28.66  ? 136 GLY B CA  1 
ATOM   4759  C C   . GLY B 1 136 ? 153.117 156.348 91.222  1.00 28.66  ? 136 GLY B C   1 
ATOM   4760  O O   . GLY B 1 136 ? 153.327 156.074 92.403  1.00 28.66  ? 136 GLY B O   1 
ATOM   4761  N N   . GLY B 1 137 ? 152.466 157.450 90.846  1.00 31.23  ? 137 GLY B N   1 
ATOM   4762  C CA  . GLY B 1 137 ? 152.071 158.465 91.800  1.00 31.23  ? 137 GLY B CA  1 
ATOM   4763  C C   . GLY B 1 137 ? 150.659 158.958 91.553  1.00 31.23  ? 137 GLY B C   1 
ATOM   4764  O O   . GLY B 1 137 ? 149.974 158.509 90.634  1.00 31.23  ? 137 GLY B O   1 
ATOM   4765  N N   . SER B 1 138 ? 150.240 159.900 92.396  1.00 31.71  ? 138 SER B N   1 
ATOM   4766  C CA  . SER B 1 138 ? 148.889 160.438 92.347  1.00 31.71  ? 138 SER B CA  1 
ATOM   4767  C C   . SER B 1 138 ? 148.892 161.860 92.888  1.00 31.71  ? 138 SER B C   1 
ATOM   4768  O O   . SER B 1 138 ? 149.756 162.236 93.682  1.00 31.71  ? 138 SER B O   1 
ATOM   4769  C CB  . SER B 1 138 ? 147.918 159.568 93.152  1.00 31.71  ? 138 SER B CB  1 
ATOM   4770  O OG  . SER B 1 138 ? 146.577 159.972 92.961  1.00 31.71  ? 138 SER B OG  1 
ATOM   4771  N N   . SER B 1 139 ? 147.908 162.647 92.457  1.00 32.28  ? 139 SER B N   1 
ATOM   4772  C CA  . SER B 1 139 ? 147.731 163.984 93.006  1.00 32.28  ? 139 SER B CA  1 
ATOM   4773  C C   . SER B 1 139 ? 147.051 163.971 94.368  1.00 32.28  ? 139 SER B C   1 
ATOM   4774  O O   . SER B 1 139 ? 147.052 164.998 95.053  1.00 32.28  ? 139 SER B O   1 
ATOM   4775  C CB  . SER B 1 139 ? 146.934 164.856 92.033  1.00 32.28  ? 139 SER B CB  1 
ATOM   4776  O OG  . SER B 1 139 ? 145.610 164.379 91.884  1.00 32.28  ? 139 SER B OG  1 
ATOM   4777  N N   . ALA B 1 140 ? 146.486 162.837 94.781  1.00 29.76  ? 140 ALA B N   1 
ATOM   4778  C CA  . ALA B 1 140 ? 145.925 162.699 96.116  1.00 29.76  ? 140 ALA B CA  1 
ATOM   4779  C C   . ALA B 1 140 ? 146.987 162.497 97.187  1.00 29.76  ? 140 ALA B C   1 
ATOM   4780  O O   . ALA B 1 140 ? 146.650 162.495 98.375  1.00 29.76  ? 140 ALA B O   1 
ATOM   4781  C CB  . ALA B 1 140 ? 144.938 161.532 96.152  1.00 29.76  ? 140 ALA B CB  1 
ATOM   4782  N N   . CYS B 1 141 ? 148.249 162.313 96.801  1.00 32.21  ? 141 CYS B N   1 
ATOM   4783  C CA  . CYS B 1 141 ? 149.346 162.072 97.741  1.00 32.21  ? 141 CYS B CA  1 
ATOM   4784  C C   . CYS B 1 141 ? 150.545 162.876 97.242  1.00 32.21  ? 141 CYS B C   1 
ATOM   4785  O O   . CYS B 1 141 ? 151.374 162.363 96.490  1.00 32.21  ? 141 CYS B O   1 
ATOM   4786  C CB  . CYS B 1 141 ? 149.654 160.581 97.831  1.00 32.21  ? 141 CYS B CB  1 
ATOM   4787  S SG  . CYS B 1 141 ? 150.602 160.053 99.272  1.00 32.21  ? 141 CYS B SG  1 
ATOM   4788  N N   . LYS B 1 142 ? 150.649 164.124 97.684  1.00 36.32  ? 142 LYS B N   1 
ATOM   4789  C CA  . LYS B 1 142 ? 151.665 165.041 97.186  1.00 36.32  ? 142 LYS B CA  1 
ATOM   4790  C C   . LYS B 1 142 ? 152.886 165.052 98.094  1.00 36.32  ? 142 LYS B C   1 
ATOM   4791  O O   . LYS B 1 142 ? 152.763 165.105 99.320  1.00 36.32  ? 142 LYS B O   1 
ATOM   4792  C CB  . LYS B 1 142 ? 151.108 166.460 97.062  1.00 36.32  ? 142 LYS B CB  1 
ATOM   4793  C CG  . LYS B 1 142 ? 149.994 166.605 96.048  1.00 36.32  ? 142 LYS B CG  1 
ATOM   4794  C CD  . LYS B 1 142 ? 150.438 167.450 94.869  1.00 36.32  ? 142 LYS B CD  1 
ATOM   4795  C CE  . LYS B 1 142 ? 149.325 167.595 93.849  1.00 36.32  ? 142 LYS B CE  1 
ATOM   4796  N NZ  . LYS B 1 142 ? 149.855 167.738 92.465  1.00 36.32  ? 142 LYS B NZ  1 
ATOM   4797  N N   . ARG B 1 143 ? 154.064 164.999 97.482  1.00 36.43  ? 143 ARG B N   1 
ATOM   4798  C CA  . ARG B 1 143 ? 155.337 165.200 98.168  1.00 36.43  ? 143 ARG B CA  1 
ATOM   4799  C C   . ARG B 1 143 ? 155.923 166.500 97.623  1.00 36.43  ? 143 ARG B C   1 
ATOM   4800  O O   . ARG B 1 143 ? 156.687 166.500 96.658  1.00 36.43  ? 143 ARG B O   1 
ATOM   4801  C CB  . ARG B 1 143 ? 156.281 164.020 97.960  1.00 36.43  ? 143 ARG B CB  1 
ATOM   4802  C CG  . ARG B 1 143 ? 155.676 162.674 98.316  1.00 36.43  ? 143 ARG B CG  1 
ATOM   4803  C CD  . ARG B 1 143 ? 156.696 161.555 98.194  1.00 36.43  ? 143 ARG B CD  1 
ATOM   4804  N NE  . ARG B 1 143 ? 156.412 160.459 99.112  1.00 36.43  ? 143 ARG B NE  1 
ATOM   4805  C CZ  . ARG B 1 143 ? 156.706 160.465 100.405 1.00 36.43  ? 143 ARG B CZ  1 
ATOM   4806  N NH1 . ARG B 1 143 ? 157.322 161.490 100.969 1.00 36.43  ? 143 ARG B NH1 1 
ATOM   4807  N NH2 . ARG B 1 143 ? 156.373 159.416 101.150 1.00 36.43  ? 143 ARG B NH2 1 
ATOM   4808  N N   . GLY B 1 144 ? 155.550 167.613 98.248  1.00 40.87  ? 144 GLY B N   1 
ATOM   4809  C CA  . GLY B 1 144 ? 155.922 168.918 97.763  1.00 40.87  ? 144 GLY B CA  1 
ATOM   4810  C C   . GLY B 1 144 ? 155.039 169.357 96.614  1.00 40.87  ? 144 GLY B C   1 
ATOM   4811  O O   . GLY B 1 144 ? 153.810 169.395 96.725  1.00 40.87  ? 144 GLY B O   1 
ATOM   4812  N N   . PRO B 1 145 ? 155.651 169.710 95.485  1.00 42.32  ? 145 PRO B N   1 
ATOM   4813  C CA  . PRO B 1 145 ? 154.859 170.093 94.309  1.00 42.32  ? 145 PRO B CA  1 
ATOM   4814  C C   . PRO B 1 145 ? 154.488 168.913 93.420  1.00 42.32  ? 145 PRO B C   1 
ATOM   4815  O O   . PRO B 1 145 ? 153.519 168.986 92.658  1.00 42.32  ? 145 PRO B O   1 
ATOM   4816  C CB  . PRO B 1 145 ? 155.782 171.073 93.577  1.00 42.32  ? 145 PRO B CB  1 
ATOM   4817  C CG  . PRO B 1 145 ? 157.168 170.660 93.970  1.00 42.32  ? 145 PRO B CG  1 
ATOM   4818  C CD  . PRO B 1 145 ? 157.097 169.902 95.274  1.00 42.32  ? 145 PRO B CD  1 
ATOM   4819  N N   . ALA B 1 146 ? 155.243 167.825 93.509  1.00 38.14  ? 146 ALA B N   1 
ATOM   4820  C CA  . ALA B 1 146 ? 155.073 166.694 92.611  1.00 38.14  ? 146 ALA B CA  1 
ATOM   4821  C C   . ALA B 1 146 ? 154.075 165.684 93.167  1.00 38.14  ? 146 ALA B C   1 
ATOM   4822  O O   . ALA B 1 146 ? 153.778 165.655 94.363  1.00 38.14  ? 146 ALA B O   1 
ATOM   4823  C CB  . ALA B 1 146 ? 156.414 166.009 92.354  1.00 38.14  ? 146 ALA B CB  1 
ATOM   4824  N N   . ASN B 1 147 ? 153.554 164.850 92.269  1.00 34.47  ? 147 ASN B N   1 
ATOM   4825  C CA  . ASN B 1 147 ? 152.713 163.731 92.668  1.00 34.47  ? 147 ASN B CA  1 
ATOM   4826  C C   . ASN B 1 147 ? 153.561 162.637 93.306  1.00 34.47  ? 147 ASN B C   1 
ATOM   4827  O O   . ASN B 1 147 ? 154.672 162.350 92.855  1.00 34.47  ? 147 ASN B O   1 
ATOM   4828  C CB  . ASN B 1 147 ? 151.962 163.171 91.460  1.00 34.47  ? 147 ASN B CB  1 
ATOM   4829  C CG  . ASN B 1 147 ? 150.889 164.111 90.948  1.00 34.47  ? 147 ASN B CG  1 
ATOM   4830  O OD1 . ASN B 1 147 ? 150.605 165.140 91.557  1.00 34.47  ? 147 ASN B OD1 1 
ATOM   4831  N ND2 . ASN B 1 147 ? 150.288 163.761 89.821  1.00 34.47  ? 147 ASN B ND2 1 
ATOM   4832  N N   . GLY B 1 148 ? 153.032 162.021 94.360  1.00 30.72  ? 148 GLY B N   1 
ATOM   4833  C CA  . GLY B 1 148 ? 153.773 160.997 95.070  1.00 30.72  ? 148 GLY B CA  1 
ATOM   4834  C C   . GLY B 1 148 ? 152.941 159.800 95.482  1.00 30.72  ? 148 GLY B C   1 
ATOM   4835  O O   . GLY B 1 148 ? 151.847 159.584 94.956  1.00 30.72  ? 148 GLY B O   1 
ATOM   4836  N N   . PHE B 1 149 ? 153.449 159.023 96.433  1.00 25.18  ? 149 PHE B N   1 
ATOM   4837  C CA  . PHE B 1 149 ? 152.816 157.783 96.861  1.00 25.18  ? 149 PHE B CA  1 
ATOM   4838  C C   . PHE B 1 149 ? 153.386 157.409 98.224  1.00 25.18  ? 149 PHE B C   1 
ATOM   4839  O O   . PHE B 1 149 ? 154.278 158.082 98.747  1.00 25.18  ? 149 PHE B O   1 
ATOM   4840  C CB  . PHE B 1 149 ? 153.038 156.676 95.826  1.00 25.18  ? 149 PHE B CB  1 
ATOM   4841  C CG  . PHE B 1 149 ? 152.056 155.546 95.913  1.00 25.18  ? 149 PHE B CG  1 
ATOM   4842  C CD1 . PHE B 1 149 ? 150.697 155.777 95.802  1.00 25.18  ? 149 PHE B CD1 1 
ATOM   4843  C CD2 . PHE B 1 149 ? 152.496 154.246 96.084  1.00 25.18  ? 149 PHE B CD2 1 
ATOM   4844  C CE1 . PHE B 1 149 ? 149.796 154.733 95.875  1.00 25.18  ? 149 PHE B CE1 1 
ATOM   4845  C CE2 . PHE B 1 149 ? 151.601 153.201 96.156  1.00 25.18  ? 149 PHE B CE2 1 
ATOM   4846  C CZ  . PHE B 1 149 ? 150.250 153.444 96.050  1.00 25.18  ? 149 PHE B CZ  1 
ATOM   4847  N N   . PHE B 1 150 ? 152.856 156.332 98.801  1.00 24.36  ? 150 PHE B N   1 
ATOM   4848  C CA  . PHE B 1 150 ? 153.404 155.795 100.040 1.00 24.36  ? 150 PHE B CA  1 
ATOM   4849  C C   . PHE B 1 150 ? 154.867 155.416 99.849  1.00 24.36  ? 150 PHE B C   1 
ATOM   4850  O O   . PHE B 1 150 ? 155.246 154.830 98.833  1.00 24.36  ? 150 PHE B O   1 
ATOM   4851  C CB  . PHE B 1 150 ? 152.606 154.571 100.493 1.00 24.36  ? 150 PHE B CB  1 
ATOM   4852  C CG  . PHE B 1 150 ? 151.158 154.850 100.767 1.00 24.36  ? 150 PHE B CG  1 
ATOM   4853  C CD1 . PHE B 1 150 ? 150.762 155.420 101.965 1.00 24.36  ? 150 PHE B CD1 1 
ATOM   4854  C CD2 . PHE B 1 150 ? 150.189 154.534 99.830  1.00 24.36  ? 150 PHE B CD2 1 
ATOM   4855  C CE1 . PHE B 1 150 ? 149.430 155.670 102.220 1.00 24.36  ? 150 PHE B CE1 1 
ATOM   4856  C CE2 . PHE B 1 150 ? 148.854 154.782 100.081 1.00 24.36  ? 150 PHE B CE2 1 
ATOM   4857  C CZ  . PHE B 1 150 ? 148.474 155.353 101.276 1.00 24.36  ? 150 PHE B CZ  1 
ATOM   4858  N N   . SER B 1 151 ? 155.694 155.746 100.843 1.00 25.57  ? 151 SER B N   1 
ATOM   4859  C CA  . SER B 1 151 ? 157.135 155.576 100.692 1.00 25.57  ? 151 SER B CA  1 
ATOM   4860  C C   . SER B 1 151 ? 157.574 154.117 100.752 1.00 25.57  ? 151 SER B C   1 
ATOM   4861  O O   . SER B 1 151 ? 158.654 153.794 100.252 1.00 25.57  ? 151 SER B O   1 
ATOM   4862  C CB  . SER B 1 151 ? 157.878 156.390 101.755 1.00 25.57  ? 151 SER B CB  1 
ATOM   4863  O OG  . SER B 1 151 ? 157.782 155.788 103.031 1.00 25.57  ? 151 SER B OG  1 
ATOM   4864  N N   . ARG B 1 152 ? 156.774 153.231 101.341 1.00 24.52  ? 152 ARG B N   1 
ATOM   4865  C CA  . ARG B 1 152 ? 157.140 151.827 101.473 1.00 24.52  ? 152 ARG B CA  1 
ATOM   4866  C C   . ARG B 1 152 ? 156.493 150.929 100.424 1.00 24.52  ? 152 ARG B C   1 
ATOM   4867  O O   . ARG B 1 152 ? 156.659 149.709 100.492 1.00 24.52  ? 152 ARG B O   1 
ATOM   4868  C CB  . ARG B 1 152 ? 156.785 151.315 102.875 1.00 24.52  ? 152 ARG B CB  1 
ATOM   4869  C CG  . ARG B 1 152 ? 157.393 152.119 104.016 1.00 24.52  ? 152 ARG B CG  1 
ATOM   4870  C CD  . ARG B 1 152 ? 158.909 152.150 103.939 1.00 24.52  ? 152 ARG B CD  1 
ATOM   4871  N NE  . ARG B 1 152 ? 159.510 152.569 105.199 1.00 24.52  ? 152 ARG B NE  1 
ATOM   4872  C CZ  . ARG B 1 152 ? 160.729 153.076 105.317 1.00 24.52  ? 152 ARG B CZ  1 
ATOM   4873  N NH1 . ARG B 1 152 ? 161.508 153.257 104.265 1.00 24.52  ? 152 ARG B NH1 1 
ATOM   4874  N NH2 . ARG B 1 152 ? 161.179 153.410 106.523 1.00 24.52  ? 152 ARG B NH2 1 
ATOM   4875  N N   . LEU B 1 153 ? 155.770 151.491 99.459  1.00 23.22  ? 153 LEU B N   1 
ATOM   4876  C CA  . LEU B 1 153 ? 155.099 150.707 98.433  1.00 23.22  ? 153 LEU B CA  1 
ATOM   4877  C C   . LEU B 1 153 ? 155.494 151.221 97.056  1.00 23.22  ? 153 LEU B C   1 
ATOM   4878  O O   . LEU B 1 153 ? 155.819 152.398 96.887  1.00 23.22  ? 153 LEU B O   1 
ATOM   4879  C CB  . LEU B 1 153 ? 153.573 150.752 98.600  1.00 23.22  ? 153 LEU B CB  1 
ATOM   4880  C CG  . LEU B 1 153 ? 153.000 150.278 99.940  1.00 23.22  ? 153 LEU B CG  1 
ATOM   4881  C CD1 . LEU B 1 153 ? 151.569 150.763 100.126 1.00 23.22  ? 153 LEU B CD1 1 
ATOM   4882  C CD2 . LEU B 1 153 ? 153.069 148.767 100.062 1.00 23.22  ? 153 LEU B CD2 1 
ATOM   4883  N N   . ASN B 1 154 ? 155.462 150.324 96.070  1.00 23.55  ? 154 ASN B N   1 
ATOM   4884  C CA  . ASN B 1 154 ? 155.869 150.616 94.699  1.00 23.55  ? 154 ASN B CA  1 
ATOM   4885  C C   . ASN B 1 154 ? 154.700 150.301 93.771  1.00 23.55  ? 154 ASN B C   1 
ATOM   4886  O O   . ASN B 1 154 ? 154.305 149.140 93.635  1.00 23.55  ? 154 ASN B O   1 
ATOM   4887  C CB  . ASN B 1 154 ? 157.113 149.806 94.329  1.00 23.55  ? 154 ASN B CB  1 
ATOM   4888  C CG  . ASN B 1 154 ? 157.750 150.261 93.031  1.00 23.55  ? 154 ASN B CG  1 
ATOM   4889  O OD1 . ASN B 1 154 ? 157.258 151.169 92.366  1.00 23.55  ? 154 ASN B OD1 1 
ATOM   4890  N ND2 . ASN B 1 154 ? 158.852 149.623 92.664  1.00 23.55  ? 154 ASN B ND2 1 
ATOM   4891  N N   . TRP B 1 155 ? 154.145 151.333 93.139  1.00 26.00  ? 155 TRP B N   1 
ATOM   4892  C CA  . TRP B 1 155 ? 152.989 151.188 92.259  1.00 26.00  ? 155 TRP B CA  1 
ATOM   4893  C C   . TRP B 1 155 ? 153.474 150.825 90.858  1.00 26.00  ? 155 TRP B C   1 
ATOM   4894  O O   . TRP B 1 155 ? 154.085 151.650 90.173  1.00 26.00  ? 155 TRP B O   1 
ATOM   4895  C CB  . TRP B 1 155 ? 152.165 152.475 92.246  1.00 26.00  ? 155 TRP B CB  1 
ATOM   4896  C CG  . TRP B 1 155 ? 150.806 152.350 91.615  1.00 26.00  ? 155 TRP B CG  1 
ATOM   4897  C CD1 . TRP B 1 155 ? 150.336 151.308 90.872  1.00 26.00  ? 155 TRP B CD1 1 
ATOM   4898  C CD2 . TRP B 1 155 ? 149.742 153.308 91.676  1.00 26.00  ? 155 TRP B CD2 1 
ATOM   4899  N NE1 . TRP B 1 155 ? 149.050 151.555 90.467  1.00 26.00  ? 155 TRP B NE1 1 
ATOM   4900  C CE2 . TRP B 1 155 ? 148.661 152.777 90.947  1.00 26.00  ? 155 TRP B CE2 1 
ATOM   4901  C CE3 . TRP B 1 155 ? 149.600 154.563 92.276  1.00 26.00  ? 155 TRP B CE3 1 
ATOM   4902  C CZ2 . TRP B 1 155 ? 147.453 153.456 90.804  1.00 26.00  ? 155 TRP B CZ2 1 
ATOM   4903  C CZ3 . TRP B 1 155 ? 148.401 155.235 92.131  1.00 26.00  ? 155 TRP B CZ3 1 
ATOM   4904  C CH2 . TRP B 1 155 ? 147.343 154.681 91.401  1.00 26.00  ? 155 TRP B CH2 1 
ATOM   4905  N N   . LEU B 1 156 ? 153.189 149.600 90.428  1.00 26.84  ? 156 LEU B N   1 
ATOM   4906  C CA  . LEU B 1 156 ? 153.627 149.115 89.127  1.00 26.84  ? 156 LEU B CA  1 
ATOM   4907  C C   . LEU B 1 156 ? 152.563 149.375 88.068  1.00 26.84  ? 156 LEU B C   1 
ATOM   4908  O O   . LEU B 1 156 ? 151.361 149.331 88.340  1.00 26.84  ? 156 LEU B O   1 
ATOM   4909  C CB  . LEU B 1 156 ? 153.954 147.621 89.184  1.00 26.84  ? 156 LEU B CB  1 
ATOM   4910  C CG  . LEU B 1 156 ? 155.000 147.159 90.205  1.00 26.84  ? 156 LEU B CG  1 
ATOM   4911  C CD1 . LEU B 1 156 ? 155.230 145.662 90.102  1.00 26.84  ? 156 LEU B CD1 1 
ATOM   4912  C CD2 . LEU B 1 156 ? 156.312 147.916 90.046  1.00 26.84  ? 156 LEU B CD2 1 
ATOM   4913  N N   . THR B 1 157 ? 153.022 149.638 86.847  1.00 30.12  ? 157 THR B N   1 
ATOM   4914  C CA  . THR B 1 157 ? 152.147 150.023 85.749  1.00 30.12  ? 157 THR B CA  1 
ATOM   4915  C C   . THR B 1 157 ? 152.797 149.584 84.440  1.00 30.12  ? 157 THR B C   1 
ATOM   4916  O O   . THR B 1 157 ? 154.006 149.350 84.379  1.00 30.12  ? 157 THR B O   1 
ATOM   4917  C CB  . THR B 1 157 ? 151.854 151.539 85.809  1.00 30.12  ? 157 THR B CB  1 
ATOM   4918  O OG1 . THR B 1 157 ? 150.491 151.757 86.199  1.00 30.12  ? 157 THR B OG1 1 
ATOM   4919  C CG2 . THR B 1 157 ? 152.139 152.252 84.498  1.00 30.12  ? 157 THR B CG2 1 
ATOM   4920  N N   . LYS B 1 158 ? 151.975 149.445 83.398  1.00 32.07  ? 158 LYS B N   1 
ATOM   4921  C CA  . LYS B 1 158 ? 152.442 148.921 82.119  1.00 32.07  ? 158 LYS B CA  1 
ATOM   4922  C C   . LYS B 1 158 ? 153.605 149.743 81.567  1.00 32.07  ? 158 LYS B C   1 
ATOM   4923  O O   . LYS B 1 158 ? 153.746 150.936 81.846  1.00 32.07  ? 158 LYS B O   1 
ATOM   4924  C CB  . LYS B 1 158 ? 151.300 148.902 81.101  1.00 32.07  ? 158 LYS B CB  1 
ATOM   4925  C CG  . LYS B 1 158 ? 151.033 150.255 80.464  1.00 32.07  ? 158 LYS B CG  1 
ATOM   4926  C CD  . LYS B 1 158 ? 150.047 150.173 79.319  1.00 32.07  ? 158 LYS B CD  1 
ATOM   4927  C CE  . LYS B 1 158 ? 149.702 151.566 78.815  1.00 32.07  ? 158 LYS B CE  1 
ATOM   4928  N NZ  . LYS B 1 158 ? 148.649 151.550 77.770  1.00 32.07  ? 158 LYS B NZ  1 
ATOM   4929  N N   . SER B 1 159 ? 154.448 149.082 80.778  1.00 35.03  ? 159 SER B N   1 
ATOM   4930  C CA  . SER B 1 159 ? 155.582 149.715 80.115  1.00 35.03  ? 159 SER B CA  1 
ATOM   4931  C C   . SER B 1 159 ? 155.389 149.585 78.613  1.00 35.03  ? 159 SER B C   1 
ATOM   4932  O O   . SER B 1 159 ? 155.318 148.469 78.088  1.00 35.03  ? 159 SER B O   1 
ATOM   4933  C CB  . SER B 1 159 ? 156.903 149.076 80.546  1.00 35.03  ? 159 SER B CB  1 
ATOM   4934  O OG  . SER B 1 159 ? 158.003 149.705 79.914  1.00 35.03  ? 159 SER B OG  1 
ATOM   4935  N N   . GLY B 1 160 ? 155.309 150.718 77.925  1.00 37.26  ? 160 GLY B N   1 
ATOM   4936  C CA  . GLY B 1 160 ? 155.007 150.700 76.509  1.00 37.26  ? 160 GLY B CA  1 
ATOM   4937  C C   . GLY B 1 160 ? 153.567 150.318 76.251  1.00 37.26  ? 160 GLY B C   1 
ATOM   4938  O O   . GLY B 1 160 ? 152.652 151.102 76.516  1.00 37.26  ? 160 GLY B O   1 
ATOM   4939  N N   . SER B 1 161 ? 153.349 149.107 75.734  1.00 37.87  ? 161 SER B N   1 
ATOM   4940  C CA  . SER B 1 161 ? 152.002 148.609 75.483  1.00 37.87  ? 161 SER B CA  1 
ATOM   4941  C C   . SER B 1 161 ? 151.786 147.212 76.057  1.00 37.87  ? 161 SER B C   1 
ATOM   4942  O O   . SER B 1 161 ? 150.850 146.522 75.645  1.00 37.87  ? 161 SER B O   1 
ATOM   4943  C CB  . SER B 1 161 ? 151.699 148.614 73.983  1.00 37.87  ? 161 SER B CB  1 
ATOM   4944  O OG  . SER B 1 161 ? 152.150 147.420 73.369  1.00 37.87  ? 161 SER B OG  1 
ATOM   4945  N N   . SER B 1 162 ? 152.620 146.779 77.000  1.00 35.36  ? 162 SER B N   1 
ATOM   4946  C CA  . SER B 1 162 ? 152.519 145.430 77.537  1.00 35.36  ? 162 SER B CA  1 
ATOM   4947  C C   . SER B 1 162 ? 152.686 145.445 79.050  1.00 35.36  ? 162 SER B C   1 
ATOM   4948  O O   . SER B 1 162 ? 153.343 146.322 79.613  1.00 35.36  ? 162 SER B O   1 
ATOM   4949  C CB  . SER B 1 162 ? 153.564 144.499 76.909  1.00 35.36  ? 162 SER B CB  1 
ATOM   4950  O OG  . SER B 1 162 ? 154.877 144.934 77.208  1.00 35.36  ? 162 SER B OG  1 
ATOM   4951  N N   . TYR B 1 163 ? 152.073 144.456 79.698  1.00 31.06  ? 163 TYR B N   1 
ATOM   4952  C CA  . TYR B 1 163 ? 152.231 144.220 81.132  1.00 31.06  ? 163 TYR B CA  1 
ATOM   4953  C C   . TYR B 1 163 ? 152.425 142.721 81.301  1.00 31.06  ? 163 TYR B C   1 
ATOM   4954  O O   . TYR B 1 163 ? 151.454 141.959 81.386  1.00 31.06  ? 163 TYR B O   1 
ATOM   4955  C CB  . TYR B 1 163 ? 151.025 144.730 81.922  1.00 31.06  ? 163 TYR B CB  1 
ATOM   4956  C CG  . TYR B 1 163 ? 151.164 144.714 83.437  1.00 31.06  ? 163 TYR B CG  1 
ATOM   4957  C CD1 . TYR B 1 163 ? 151.223 143.520 84.144  1.00 31.06  ? 163 TYR B CD1 1 
ATOM   4958  C CD2 . TYR B 1 163 ? 151.206 145.899 84.160  1.00 31.06  ? 163 TYR B CD2 1 
ATOM   4959  C CE1 . TYR B 1 163 ? 151.336 143.505 85.519  1.00 31.06  ? 163 TYR B CE1 1 
ATOM   4960  C CE2 . TYR B 1 163 ? 151.315 145.895 85.538  1.00 31.06  ? 163 TYR B CE2 1 
ATOM   4961  C CZ  . TYR B 1 163 ? 151.380 144.694 86.212  1.00 31.06  ? 163 TYR B CZ  1 
ATOM   4962  O OH  . TYR B 1 163 ? 151.492 144.675 87.580  1.00 31.06  ? 163 TYR B OH  1 
ATOM   4963  N N   . PRO B 1 164 ? 153.669 142.260 81.349  1.00 32.73  ? 164 PRO B N   1 
ATOM   4964  C CA  . PRO B 1 164 ? 153.935 140.819 81.357  1.00 32.73  ? 164 PRO B CA  1 
ATOM   4965  C C   . PRO B 1 164 ? 153.632 140.200 82.715  1.00 32.73  ? 164 PRO B C   1 
ATOM   4966  O O   . PRO B 1 164 ? 153.397 140.884 83.710  1.00 32.73  ? 164 PRO B O   1 
ATOM   4967  C CB  . PRO B 1 164 ? 155.433 140.728 81.032  1.00 32.73  ? 164 PRO B CB  1 
ATOM   4968  C CG  . PRO B 1 164 ? 155.893 142.153 80.786  1.00 32.73  ? 164 PRO B CG  1 
ATOM   4969  C CD  . PRO B 1 164 ? 154.910 143.035 81.468  1.00 32.73  ? 164 PRO B CD  1 
ATOM   4970  N N   . LEU B 1 165 ? 153.638 138.871 82.733  1.00 30.97  ? 165 LEU B N   1 
ATOM   4971  C CA  . LEU B 1 165 ? 153.435 138.135 83.972  1.00 30.97  ? 165 LEU B CA  1 
ATOM   4972  C C   . LEU B 1 165 ? 154.693 138.201 84.831  1.00 30.97  ? 165 LEU B C   1 
ATOM   4973  O O   . LEU B 1 165 ? 155.799 137.935 84.353  1.00 30.97  ? 165 LEU B O   1 
ATOM   4974  C CB  . LEU B 1 165 ? 153.070 136.684 83.667  1.00 30.97  ? 165 LEU B CB  1 
ATOM   4975  C CG  . LEU B 1 165 ? 152.991 135.718 84.849  1.00 30.97  ? 165 LEU B CG  1 
ATOM   4976  C CD1 . LEU B 1 165 ? 151.762 135.993 85.695  1.00 30.97  ? 165 LEU B CD1 1 
ATOM   4977  C CD2 . LEU B 1 165 ? 152.999 134.282 84.359  1.00 30.97  ? 165 LEU B CD2 1 
ATOM   4978  N N   . LEU B 1 166 ? 154.524 138.550 86.102  1.00 29.80  ? 166 LEU B N   1 
ATOM   4979  C CA  . LEU B 1 166 ? 155.639 138.701 87.026  1.00 29.80  ? 166 LEU B CA  1 
ATOM   4980  C C   . LEU B 1 166 ? 155.701 137.506 87.968  1.00 29.80  ? 166 LEU B C   1 
ATOM   4981  O O   . LEU B 1 166 ? 154.702 137.180 88.620  1.00 29.80  ? 166 LEU B O   1 
ATOM   4982  C CB  . LEU B 1 166 ? 155.502 139.995 87.830  1.00 29.80  ? 166 LEU B CB  1 
ATOM   4983  C CG  . LEU B 1 166 ? 155.317 141.305 87.059  1.00 29.80  ? 166 LEU B CG  1 
ATOM   4984  C CD1 . LEU B 1 166 ? 154.590 142.327 87.913  1.00 29.80  ? 166 LEU B CD1 1 
ATOM   4985  C CD2 . LEU B 1 166 ? 156.651 141.857 86.594  1.00 29.80  ? 166 LEU B CD2 1 
ATOM   4986  N N   . ASN B 1 167 ? 156.871 136.856 88.029  1.00 31.50  ? 167 ASN B N   1 
ATOM   4987  C CA  . ASN B 1 167 ? 157.169 135.824 89.022  1.00 31.50  ? 167 ASN B CA  1 
ATOM   4988  C C   . ASN B 1 167 ? 158.461 136.224 89.718  1.00 31.50  ? 167 ASN B C   1 
ATOM   4989  O O   . ASN B 1 167 ? 159.538 136.119 89.125  1.00 31.50  ? 167 ASN B O   1 
ATOM   4990  C CB  . ASN B 1 167 ? 157.338 134.427 88.407  1.00 31.50  ? 167 ASN B CB  1 
ATOM   4991  C CG  . ASN B 1 167 ? 156.375 133.431 89.001  1.00 31.50  ? 167 ASN B CG  1 
ATOM   4992  O OD1 . ASN B 1 167 ? 155.219 133.786 89.184  1.00 31.50  ? 167 ASN B OD1 1 
ATOM   4993  N ND2 . ASN B 1 167 ? 156.802 132.208 89.343  1.00 31.50  ? 167 ASN B ND2 1 
ATOM   4994  N N   . VAL B 1 168 ? 158.372 136.668 90.968  1.00 28.79  ? 168 VAL B N   1 
ATOM   4995  C CA  . VAL B 1 168 ? 159.575 137.016 91.715  1.00 28.79  ? 168 VAL B CA  1 
ATOM   4996  C C   . VAL B 1 168 ? 159.614 136.209 93.004  1.00 28.79  ? 168 VAL B C   1 
ATOM   4997  O O   . VAL B 1 168 ? 158.578 135.807 93.544  1.00 28.79  ? 168 VAL B O   1 
ATOM   4998  C CB  . VAL B 1 168 ? 159.675 138.528 92.017  1.00 28.79  ? 168 VAL B CB  1 
ATOM   4999  C CG1 . VAL B 1 168 ? 159.573 139.338 90.735  1.00 28.79  ? 168 VAL B CG1 1 
ATOM   5000  C CG2 . VAL B 1 168 ? 158.612 138.946 93.012  1.00 28.79  ? 168 VAL B CG2 1 
ATOM   5001  N N   . THR B 1 169 ? 160.829 135.971 93.492  1.00 30.11  ? 169 THR B N   1 
ATOM   5002  C CA  . THR B 1 169 ? 161.049 135.161 94.680  1.00 30.11  ? 169 THR B CA  1 
ATOM   5003  C C   . THR B 1 169 ? 162.092 135.822 95.571  1.00 30.11  ? 169 THR B C   1 
ATOM   5004  O O   . THR B 1 169 ? 163.029 136.465 95.091  1.00 30.11  ? 169 THR B O   1 
ATOM   5005  C CB  . THR B 1 169 ? 161.484 133.731 94.309  1.00 30.11  ? 169 THR B CB  1 
ATOM   5006  O OG1 . THR B 1 169 ? 161.754 132.981 95.498  1.00 30.11  ? 169 THR B OG1 1 
ATOM   5007  C CG2 . THR B 1 169 ? 162.721 133.750 93.436  1.00 30.11  ? 169 THR B CG2 1 
ATOM   5008  N N   . MET B 1 170 ? 161.909 135.664 96.878  1.00 30.56  ? 170 MET B N   1 
ATOM   5009  C CA  . MET B 1 170 ? 162.822 136.198 97.880  1.00 30.56  ? 170 MET B CA  1 
ATOM   5010  C C   . MET B 1 170 ? 162.941 135.224 99.047  1.00 30.56  ? 170 MET B C   1 
ATOM   5011  O O   . MET B 1 170 ? 161.950 134.957 99.738  1.00 30.56  ? 170 MET B O   1 
ATOM   5012  C CB  . MET B 1 170 ? 162.350 137.571 98.366  1.00 30.56  ? 170 MET B CB  1 
ATOM   5013  C CG  . MET B 1 170 ? 163.431 138.425 99.026  1.00 30.56  ? 170 MET B CG  1 
ATOM   5014  S SD  . MET B 1 170 ? 164.796 138.886 97.940  1.00 30.56  ? 170 MET B SD  1 
ATOM   5015  C CE  . MET B 1 170 ? 164.054 140.210 96.991  1.00 30.56  ? 170 MET B CE  1 
ATOM   5016  N N   . PRO B 1 171 ? 164.121 134.659 99.285  1.00 31.25  ? 171 PRO B N   1 
ATOM   5017  C CA  . PRO B 1 171 ? 164.296 133.727 100.401 1.00 31.25  ? 171 PRO B CA  1 
ATOM   5018  C C   . PRO B 1 171 ? 164.662 134.433 101.697 1.00 31.25  ? 171 PRO B C   1 
ATOM   5019  O O   . PRO B 1 171 ? 165.286 135.494 101.711 1.00 31.25  ? 171 PRO B O   1 
ATOM   5020  C CB  . PRO B 1 171 ? 165.453 132.832 99.928  1.00 31.25  ? 171 PRO B CB  1 
ATOM   5021  C CG  . PRO B 1 171 ? 166.096 133.558 98.764  1.00 31.25  ? 171 PRO B CG  1 
ATOM   5022  C CD  . PRO B 1 171 ? 165.363 134.839 98.519  1.00 31.25  ? 171 PRO B CD  1 
ATOM   5023  N N   . ASN B 1 172 ? 164.252 133.819 102.803 1.00 30.89  ? 172 ASN B N   1 
ATOM   5024  C CA  . ASN B 1 172 ? 164.589 134.300 104.140 1.00 30.89  ? 172 ASN B CA  1 
ATOM   5025  C C   . ASN B 1 172 ? 165.787 133.497 104.637 1.00 30.89  ? 172 ASN B C   1 
ATOM   5026  O O   . ASN B 1 172 ? 165.644 132.362 105.094 1.00 30.89  ? 172 ASN B O   1 
ATOM   5027  C CB  . ASN B 1 172 ? 163.397 134.179 105.084 1.00 30.89  ? 172 ASN B CB  1 
ATOM   5028  C CG  . ASN B 1 172 ? 163.631 134.870 106.418 1.00 30.89  ? 172 ASN B CG  1 
ATOM   5029  O OD1 . ASN B 1 172 ? 164.745 135.281 106.730 1.00 30.89  ? 172 ASN B OD1 1 
ATOM   5030  N ND2 . ASN B 1 172 ? 162.576 135.000 107.208 1.00 30.89  ? 172 ASN B ND2 1 
ATOM   5031  N N   . ASN B 1 173 ? 166.973 134.093 104.549 1.00 35.08  ? 173 ASN B N   1 
ATOM   5032  C CA  . ASN B 1 173 ? 168.204 133.445 104.976 1.00 35.08  ? 173 ASN B CA  1 
ATOM   5033  C C   . ASN B 1 173 ? 168.721 133.980 106.305 1.00 35.08  ? 173 ASN B C   1 
ATOM   5034  O O   . ASN B 1 173 ? 169.860 133.685 106.678 1.00 35.08  ? 173 ASN B O   1 
ATOM   5035  C CB  . ASN B 1 173 ? 169.275 133.587 103.894 1.00 35.08  ? 173 ASN B CB  1 
ATOM   5036  C CG  . ASN B 1 173 ? 169.048 132.645 102.728 1.00 35.08  ? 173 ASN B CG  1 
ATOM   5037  O OD1 . ASN B 1 173 ? 168.721 131.475 102.918 1.00 35.08  ? 173 ASN B OD1 1 
ATOM   5038  N ND2 . ASN B 1 173 ? 169.218 133.151 101.515 1.00 35.08  ? 173 ASN B ND2 1 
ATOM   5039  N N   . TYR B 1 174 ? 167.915 134.758 107.020 1.00 35.25  ? 174 TYR B N   1 
ATOM   5040  C CA  . TYR B 1 174 ? 168.256 135.238 108.349 1.00 35.25  ? 174 TYR B CA  1 
ATOM   5041  C C   . TYR B 1 174 ? 167.722 134.258 109.392 1.00 35.25  ? 174 TYR B C   1 
ATOM   5042  O O   . TYR B 1 174 ? 167.241 133.171 109.065 1.00 35.25  ? 174 TYR B O   1 
ATOM   5043  C CB  . TYR B 1 174 ? 167.700 136.644 108.560 1.00 35.25  ? 174 TYR B CB  1 
ATOM   5044  C CG  . TYR B 1 174 ? 168.176 137.653 107.545 1.00 35.25  ? 174 TYR B CG  1 
ATOM   5045  C CD1 . TYR B 1 174 ? 169.507 137.703 107.161 1.00 35.25  ? 174 TYR B CD1 1 
ATOM   5046  C CD2 . TYR B 1 174 ? 167.292 138.546 106.961 1.00 35.25  ? 174 TYR B CD2 1 
ATOM   5047  C CE1 . TYR B 1 174 ? 169.945 138.624 106.233 1.00 35.25  ? 174 TYR B CE1 1 
ATOM   5048  C CE2 . TYR B 1 174 ? 167.719 139.467 106.030 1.00 35.25  ? 174 TYR B CE2 1 
ATOM   5049  C CZ  . TYR B 1 174 ? 169.047 139.503 105.671 1.00 35.25  ? 174 TYR B CZ  1 
ATOM   5050  O OH  . TYR B 1 174 ? 169.481 140.420 104.744 1.00 35.25  ? 174 TYR B OH  1 
ATOM   5051  N N   . ASN B 1 175 ? 167.790 134.640 110.667 1.00 37.08  ? 175 ASN B N   1 
ATOM   5052  C CA  . ASN B 1 175 ? 167.260 133.819 111.749 1.00 37.08  ? 175 ASN B CA  1 
ATOM   5053  C C   . ASN B 1 175 ? 166.116 134.506 112.489 1.00 37.08  ? 175 ASN B C   1 
ATOM   5054  O O   . ASN B 1 175 ? 165.817 134.145 113.630 1.00 37.08  ? 175 ASN B O   1 
ATOM   5055  C CB  . ASN B 1 175 ? 168.372 133.431 112.727 1.00 37.08  ? 175 ASN B CB  1 
ATOM   5056  C CG  . ASN B 1 175 ? 169.194 134.619 113.177 1.00 37.08  ? 175 ASN B CG  1 
ATOM   5057  O OD1 . ASN B 1 175 ? 169.126 135.697 112.589 1.00 37.08  ? 175 ASN B OD1 1 
ATOM   5058  N ND2 . ASN B 1 175 ? 169.980 134.427 114.229 1.00 37.08  ? 175 ASN B ND2 1 
ATOM   5059  N N   . PHE B 1 176 ? 165.468 135.487 111.864 1.00 32.93  ? 176 PHE B N   1 
ATOM   5060  C CA  . PHE B 1 176 ? 164.305 136.151 112.435 1.00 32.93  ? 176 PHE B CA  1 
ATOM   5061  C C   . PHE B 1 176 ? 163.200 136.225 111.388 1.00 32.93  ? 176 PHE B C   1 
ATOM   5062  O O   . PHE B 1 176 ? 163.425 136.000 110.197 1.00 32.93  ? 176 PHE B O   1 
ATOM   5063  C CB  . PHE B 1 176 ? 164.653 137.552 112.965 1.00 32.93  ? 176 PHE B CB  1 
ATOM   5064  C CG  . PHE B 1 176 ? 165.422 138.406 111.994 1.00 32.93  ? 176 PHE B CG  1 
ATOM   5065  C CD1 . PHE B 1 176 ? 164.776 139.066 110.961 1.00 32.93  ? 176 PHE B CD1 1 
ATOM   5066  C CD2 . PHE B 1 176 ? 166.790 138.562 112.125 1.00 32.93  ? 176 PHE B CD2 1 
ATOM   5067  C CE1 . PHE B 1 176 ? 165.482 139.852 110.072 1.00 32.93  ? 176 PHE B CE1 1 
ATOM   5068  C CE2 . PHE B 1 176 ? 167.500 139.350 111.240 1.00 32.93  ? 176 PHE B CE2 1 
ATOM   5069  C CZ  . PHE B 1 176 ? 166.846 139.995 110.213 1.00 32.93  ? 176 PHE B CZ  1 
ATOM   5070  N N   . ASP B 1 177 ? 161.993 136.540 111.850 1.00 31.20  ? 177 ASP B N   1 
ATOM   5071  C CA  . ASP B 1 177 ? 160.828 136.624 110.981 1.00 31.20  ? 177 ASP B CA  1 
ATOM   5072  C C   . ASP B 1 177 ? 160.836 137.912 110.167 1.00 31.20  ? 177 ASP B C   1 
ATOM   5073  O O   . ASP B 1 177 ? 161.378 138.937 110.589 1.00 31.20  ? 177 ASP B O   1 
ATOM   5074  C CB  . ASP B 1 177 ? 159.540 136.554 111.802 1.00 31.20  ? 177 ASP B CB  1 
ATOM   5075  C CG  . ASP B 1 177 ? 159.253 135.165 112.327 1.00 31.20  ? 177 ASP B CG  1 
ATOM   5076  O OD1 . ASP B 1 177 ? 160.128 134.287 112.200 1.00 31.20  ? 177 ASP B OD1 1 
ATOM   5077  O OD2 . ASP B 1 177 ? 158.152 134.953 112.874 1.00 31.20  ? 177 ASP B OD2 1 
ATOM   5078  N N   . LYS B 1 178 ? 160.218 137.853 108.990 1.00 25.80  ? 178 LYS B N   1 
ATOM   5079  C CA  . LYS B 1 178 ? 160.054 139.009 108.119 1.00 25.80  ? 178 LYS B CA  1 
ATOM   5080  C C   . LYS B 1 178 ? 158.573 139.317 107.950 1.00 25.80  ? 178 LYS B C   1 
ATOM   5081  O O   . LYS B 1 178 ? 157.757 138.403 107.816 1.00 25.80  ? 178 LYS B O   1 
ATOM   5082  C CB  . LYS B 1 178 ? 160.677 138.769 106.742 1.00 25.80  ? 178 LYS B CB  1 
ATOM   5083  C CG  . LYS B 1 178 ? 162.187 138.684 106.713 1.00 25.80  ? 178 LYS B CG  1 
ATOM   5084  C CD  . LYS B 1 178 ? 162.655 138.390 105.301 1.00 25.80  ? 178 LYS B CD  1 
ATOM   5085  C CE  . LYS B 1 178 ? 164.150 138.549 105.151 1.00 25.80  ? 178 LYS B CE  1 
ATOM   5086  N NZ  . LYS B 1 178 ? 164.566 138.469 103.726 1.00 25.80  ? 178 LYS B NZ  1 
ATOM   5087  N N   . LEU B 1 179 ? 158.229 140.602 107.952 1.00 23.65  ? 179 LEU B N   1 
ATOM   5088  C CA  . LEU B 1 179 ? 156.863 141.054 107.708 1.00 23.65  ? 179 LEU B CA  1 
ATOM   5089  C C   . LEU B 1 179 ? 156.833 141.862 106.419 1.00 23.65  ? 179 LEU B C   1 
ATOM   5090  O O   . LEU B 1 179 ? 157.544 142.863 106.294 1.00 23.65  ? 179 LEU B O   1 
ATOM   5091  C CB  . LEU B 1 179 ? 156.339 141.887 108.880 1.00 23.65  ? 179 LEU B CB  1 
ATOM   5092  C CG  . LEU B 1 179 ? 154.945 142.504 108.724 1.00 23.65  ? 179 LEU B CG  1 
ATOM   5093  C CD1 . LEU B 1 179 ? 153.859 141.440 108.747 1.00 23.65  ? 179 LEU B CD1 1 
ATOM   5094  C CD2 . LEU B 1 179 ? 154.699 143.537 109.802 1.00 23.65  ? 179 LEU B CD2 1 
ATOM   5095  N N   . TYR B 1 180 ? 156.011 141.431 105.467 1.00 22.40  ? 180 TYR B N   1 
ATOM   5096  C CA  . TYR B 1 180 ? 155.844 142.104 104.188 1.00 22.40  ? 180 TYR B CA  1 
ATOM   5097  C C   . TYR B 1 180 ? 154.451 142.716 104.120 1.00 22.40  ? 180 TYR B C   1 
ATOM   5098  O O   . TYR B 1 180 ? 153.463 142.052 104.448 1.00 22.40  ? 180 TYR B O   1 
ATOM   5099  C CB  . TYR B 1 180 ? 156.043 141.132 103.023 1.00 22.40  ? 180 TYR B CB  1 
ATOM   5100  C CG  . TYR B 1 180 ? 157.474 140.711 102.778 1.00 22.40  ? 180 TYR B CG  1 
ATOM   5101  C CD1 . TYR B 1 180 ? 158.323 141.485 102.000 1.00 22.40  ? 180 TYR B CD1 1 
ATOM   5102  C CD2 . TYR B 1 180 ? 157.971 139.531 103.312 1.00 22.40  ? 180 TYR B CD2 1 
ATOM   5103  C CE1 . TYR B 1 180 ? 159.628 141.100 101.770 1.00 22.40  ? 180 TYR B CE1 1 
ATOM   5104  C CE2 . TYR B 1 180 ? 159.272 139.138 103.086 1.00 22.40  ? 180 TYR B CE2 1 
ATOM   5105  C CZ  . TYR B 1 180 ? 160.096 139.924 102.315 1.00 22.40  ? 180 TYR B CZ  1 
ATOM   5106  O OH  . TYR B 1 180 ? 161.392 139.531 102.091 1.00 22.40  ? 180 TYR B OH  1 
ATOM   5107  N N   . ILE B 1 181 ? 154.383 143.974 103.693 1.00 20.97  ? 181 ILE B N   1 
ATOM   5108  C CA  . ILE B 1 181 ? 153.132 144.686 103.454 1.00 20.97  ? 181 ILE B CA  1 
ATOM   5109  C C   . ILE B 1 181 ? 153.011 144.931 101.956 1.00 20.97  ? 181 ILE B C   1 
ATOM   5110  O O   . ILE B 1 181 ? 153.947 145.438 101.329 1.00 20.97  ? 181 ILE B O   1 
ATOM   5111  C CB  . ILE B 1 181 ? 153.080 146.015 104.230 1.00 20.97  ? 181 ILE B CB  1 
ATOM   5112  C CG1 . ILE B 1 181 ? 153.521 145.819 105.684 1.00 20.97  ? 181 ILE B CG1 1 
ATOM   5113  C CG2 . ILE B 1 181 ? 151.692 146.639 104.150 1.00 20.97  ? 181 ILE B CG2 1 
ATOM   5114  C CD1 . ILE B 1 181 ? 152.528 145.073 106.536 1.00 20.97  ? 181 ILE B CD1 1 
ATOM   5115  N N   . TRP B 1 182 ? 151.866 144.568 101.378 1.00 20.47  ? 182 TRP B N   1 
ATOM   5116  C CA  . TRP B 1 182 ? 151.631 144.746 99.949  1.00 20.47  ? 182 TRP B CA  1 
ATOM   5117  C C   . TRP B 1 182 ? 150.174 145.143 99.735  1.00 20.47  ? 182 TRP B C   1 
ATOM   5118  O O   . TRP B 1 182 ? 149.402 145.271 100.688 1.00 20.47  ? 182 TRP B O   1 
ATOM   5119  C CB  . TRP B 1 182 ? 152.014 143.481 99.165  1.00 20.47  ? 182 TRP B CB  1 
ATOM   5120  C CG  . TRP B 1 182 ? 151.502 142.205 99.759  1.00 20.47  ? 182 TRP B CG  1 
ATOM   5121  C CD1 . TRP B 1 182 ? 152.043 141.510 100.800 1.00 20.47  ? 182 TRP B CD1 1 
ATOM   5122  C CD2 . TRP B 1 182 ? 150.350 141.466 99.340  1.00 20.47  ? 182 TRP B CD2 1 
ATOM   5123  N NE1 . TRP B 1 182 ? 151.297 140.391 101.061 1.00 20.47  ? 182 TRP B NE1 1 
ATOM   5124  C CE2 . TRP B 1 182 ? 150.252 140.338 100.178 1.00 20.47  ? 182 TRP B CE2 1 
ATOM   5125  C CE3 . TRP B 1 182 ? 149.390 141.651 98.341  1.00 20.47  ? 182 TRP B CE3 1 
ATOM   5126  C CZ2 . TRP B 1 182 ? 149.232 139.400 100.047 1.00 20.47  ? 182 TRP B CZ2 1 
ATOM   5127  C CZ3 . TRP B 1 182 ? 148.380 140.718 98.212  1.00 20.47  ? 182 TRP B CZ3 1 
ATOM   5128  C CH2 . TRP B 1 182 ? 148.308 139.606 99.061  1.00 20.47  ? 182 TRP B CH2 1 
ATOM   5129  N N   . GLY B 1 183 ? 149.790 145.350 98.476  1.00 21.31  ? 183 GLY B N   1 
ATOM   5130  C CA  . GLY B 1 183 ? 148.442 145.821 98.209  1.00 21.31  ? 183 GLY B CA  1 
ATOM   5131  C C   . GLY B 1 183 ? 147.954 145.505 96.812  1.00 21.31  ? 183 GLY B C   1 
ATOM   5132  O O   . GLY B 1 183 ? 148.698 145.030 95.952  1.00 21.31  ? 183 GLY B O   1 
ATOM   5133  N N   . VAL B 1 184 ? 146.667 145.786 96.607  1.00 23.14  ? 184 VAL B N   1 
ATOM   5134  C CA  . VAL B 1 184 ? 145.977 145.575 95.337  1.00 23.14  ? 184 VAL B CA  1 
ATOM   5135  C C   . VAL B 1 184 ? 145.176 146.828 95.004  1.00 23.14  ? 184 VAL B C   1 
ATOM   5136  O O   . VAL B 1 184 ? 144.514 147.398 95.876  1.00 23.14  ? 184 VAL B O   1 
ATOM   5137  C CB  . VAL B 1 184 ? 145.047 144.340 95.385  1.00 23.14  ? 184 VAL B CB  1 
ATOM   5138  C CG1 . VAL B 1 184 ? 144.395 144.103 94.032  1.00 23.14  ? 184 VAL B CG1 1 
ATOM   5139  C CG2 . VAL B 1 184 ? 145.800 143.101 95.846  1.00 23.14  ? 184 VAL B CG2 1 
ATOM   5140  N N   . HIS B 1 185 ? 145.216 147.247 93.741  1.00 24.19  ? 185 HIS B N   1 
ATOM   5141  C CA  . HIS B 1 185 ? 144.516 148.445 93.290  1.00 24.19  ? 185 HIS B CA  1 
ATOM   5142  C C   . HIS B 1 185 ? 143.174 148.092 92.654  1.00 24.19  ? 185 HIS B C   1 
ATOM   5143  O O   . HIS B 1 185 ? 143.100 147.203 91.800  1.00 24.19  ? 185 HIS B O   1 
ATOM   5144  C CB  . HIS B 1 185 ? 145.369 149.234 92.297  1.00 24.19  ? 185 HIS B CB  1 
ATOM   5145  C CG  . HIS B 1 185 ? 144.691 150.457 91.764  1.00 24.19  ? 185 HIS B CG  1 
ATOM   5146  N ND1 . HIS B 1 185 ? 144.493 150.670 90.418  1.00 24.19  ? 185 HIS B ND1 1 
ATOM   5147  C CD2 . HIS B 1 185 ? 144.156 151.527 92.396  1.00 24.19  ? 185 HIS B CD2 1 
ATOM   5148  C CE1 . HIS B 1 185 ? 143.868 151.820 90.244  1.00 24.19  ? 185 HIS B CE1 1 
ATOM   5149  N NE2 . HIS B 1 185 ? 143.650 152.359 91.429  1.00 24.19  ? 185 HIS B NE2 1 
ATOM   5150  N N   . HIS B 1 186 ? 142.123 148.802 93.067  1.00 25.35  ? 186 HIS B N   1 
ATOM   5151  C CA  . HIS B 1 186 ? 140.776 148.664 92.523  1.00 25.35  ? 186 HIS B CA  1 
ATOM   5152  C C   . HIS B 1 186 ? 140.446 149.881 91.669  1.00 25.35  ? 186 HIS B C   1 
ATOM   5153  O O   . HIS B 1 186 ? 140.250 150.981 92.217  1.00 25.35  ? 186 HIS B O   1 
ATOM   5154  C CB  . HIS B 1 186 ? 139.752 148.517 93.649  1.00 25.35  ? 186 HIS B CB  1 
ATOM   5155  C CG  . HIS B 1 186 ? 140.074 147.432 94.628  1.00 25.35  ? 186 HIS B CG  1 
ATOM   5156  N ND1 . HIS B 1 186 ? 140.031 146.095 94.300  1.00 25.35  ? 186 HIS B ND1 1 
ATOM   5157  C CD2 . HIS B 1 186 ? 140.436 147.487 95.931  1.00 25.35  ? 186 HIS B CD2 1 
ATOM   5158  C CE1 . HIS B 1 186 ? 140.353 145.373 95.357  1.00 25.35  ? 186 HIS B CE1 1 
ATOM   5159  N NE2 . HIS B 1 186 ? 140.605 146.194 96.360  1.00 25.35  ? 186 HIS B NE2 1 
ATOM   5160  N N   . PRO B 1 187 ? 140.382 149.742 90.348  1.00 26.94  ? 187 PRO B N   1 
ATOM   5161  C CA  . PRO B 1 187 ? 140.074 150.882 89.479  1.00 26.94  ? 187 PRO B CA  1 
ATOM   5162  C C   . PRO B 1 187 ? 138.582 151.194 89.459  1.00 26.94  ? 187 PRO B C   1 
ATOM   5163  O O   . PRO B 1 187 ? 137.746 150.442 89.958  1.00 26.94  ? 187 PRO B O   1 
ATOM   5164  C CB  . PRO B 1 187 ? 140.553 150.419 88.095  1.00 26.94  ? 187 PRO B CB  1 
ATOM   5165  C CG  . PRO B 1 187 ? 141.346 149.170 88.335  1.00 26.94  ? 187 PRO B CG  1 
ATOM   5166  C CD  . PRO B 1 187 ? 140.794 148.562 89.574  1.00 26.94  ? 187 PRO B CD  1 
ATOM   5167  N N   . SER B 1 188 ? 138.259 152.336 88.856  1.00 30.80  ? 188 SER B N   1 
ATOM   5168  C CA  . SER B 1 188 ? 136.882 152.810 88.818  1.00 30.80  ? 188 SER B CA  1 
ATOM   5169  C C   . SER B 1 188 ? 136.101 152.310 87.607  1.00 30.80  ? 188 SER B C   1 
ATOM   5170  O O   . SER B 1 188 ? 134.886 152.118 87.709  1.00 30.80  ? 188 SER B O   1 
ATOM   5171  C CB  . SER B 1 188 ? 136.850 154.340 88.853  1.00 30.80  ? 188 SER B CB  1 
ATOM   5172  O OG  . SER B 1 188 ? 137.677 154.892 87.847  1.00 30.80  ? 188 SER B OG  1 
ATOM   5173  N N   . THR B 1 189 ? 136.755 152.099 86.464  1.00 33.11  ? 189 THR B N   1 
ATOM   5174  C CA  . THR B 1 189 ? 136.072 151.653 85.254  1.00 33.11  ? 189 THR B CA  1 
ATOM   5175  C C   . THR B 1 189 ? 136.890 150.568 84.564  1.00 33.11  ? 189 THR B C   1 
ATOM   5176  O O   . THR B 1 189 ? 138.064 150.349 84.873  1.00 33.11  ? 189 THR B O   1 
ATOM   5177  C CB  . THR B 1 189 ? 135.820 152.809 84.272  1.00 33.11  ? 189 THR B CB  1 
ATOM   5178  O OG1 . THR B 1 189 ? 137.070 153.321 83.795  1.00 33.11  ? 189 THR B OG1 1 
ATOM   5179  C CG2 . THR B 1 189 ? 135.025 153.928 84.928  1.00 33.11  ? 189 THR B CG2 1 
ATOM   5180  N N   . ASN B 1 190 ? 136.245 149.885 83.614  1.00 35.26  ? 190 ASN B N   1 
ATOM   5181  C CA  . ASN B 1 190 ? 136.939 148.890 82.799  1.00 35.26  ? 190 ASN B CA  1 
ATOM   5182  C C   . ASN B 1 190 ? 137.977 149.543 81.895  1.00 35.26  ? 190 ASN B C   1 
ATOM   5183  O O   . ASN B 1 190 ? 139.051 148.975 81.654  1.00 35.26  ? 190 ASN B O   1 
ATOM   5184  C CB  . ASN B 1 190 ? 135.929 148.101 81.964  1.00 35.26  ? 190 ASN B CB  1 
ATOM   5185  C CG  . ASN B 1 190 ? 135.225 147.025 82.760  1.00 35.26  ? 190 ASN B CG  1 
ATOM   5186  O OD1 . ASN B 1 190 ? 135.303 146.992 83.986  1.00 35.26  ? 190 ASN B OD1 1 
ATOM   5187  N ND2 . ASN B 1 190 ? 134.525 146.140 82.065  1.00 35.26  ? 190 ASN B ND2 1 
ATOM   5188  N N   . GLN B 1 191 ? 137.666 150.733 81.376  1.00 35.91  ? 191 GLN B N   1 
ATOM   5189  C CA  . GLN B 1 191 ? 138.610 151.438 80.518  1.00 35.91  ? 191 GLN B CA  1 
ATOM   5190  C C   . GLN B 1 191 ? 139.873 151.813 81.280  1.00 35.91  ? 191 GLN B C   1 
ATOM   5191  O O   . GLN B 1 191 ? 140.984 151.679 80.756  1.00 35.91  ? 191 GLN B O   1 
ATOM   5192  C CB  . GLN B 1 191 ? 137.949 152.681 79.923  1.00 35.91  ? 191 GLN B CB  1 
ATOM   5193  C CG  . GLN B 1 191 ? 138.878 153.519 79.068  1.00 35.91  ? 191 GLN B CG  1 
ATOM   5194  C CD  . GLN B 1 191 ? 138.980 153.001 77.649  1.00 35.91  ? 191 GLN B CD  1 
ATOM   5195  O OE1 . GLN B 1 191 ? 139.800 152.133 77.350  1.00 35.91  ? 191 GLN B OE1 1 
ATOM   5196  N NE2 . GLN B 1 191 ? 138.148 153.533 76.763  1.00 35.91  ? 191 GLN B NE2 1 
ATOM   5197  N N   . GLU B 1 192 ? 139.724 152.282 82.521  1.00 34.66  ? 192 GLU B N   1 
ATOM   5198  C CA  . GLU B 1 192 ? 140.890 152.570 83.351  1.00 34.66  ? 192 GLU B CA  1 
ATOM   5199  C C   . GLU B 1 192 ? 141.695 151.305 83.616  1.00 34.66  ? 192 GLU B C   1 
ATOM   5200  O O   . GLU B 1 192 ? 142.932 151.328 83.592  1.00 34.66  ? 192 GLU B O   1 
ATOM   5201  C CB  . GLU B 1 192 ? 140.450 153.211 84.667  1.00 34.66  ? 192 GLU B CB  1 
ATOM   5202  C CG  . GLU B 1 192 ? 141.577 153.829 85.475  1.00 34.66  ? 192 GLU B CG  1 
ATOM   5203  C CD  . GLU B 1 192 ? 141.070 154.692 86.615  1.00 34.66  ? 192 GLU B CD  1 
ATOM   5204  O OE1 . GLU B 1 192 ? 140.488 154.139 87.570  1.00 34.66  ? 192 GLU B OE1 1 
ATOM   5205  O OE2 . GLU B 1 192 ? 141.253 155.925 86.555  1.00 34.66  ? 192 GLU B OE2 1 
ATOM   5206  N N   . GLN B 1 193 ? 141.004 150.192 83.872  1.00 31.37  ? 193 GLN B N   1 
ATOM   5207  C CA  . GLN B 1 193 ? 141.682 148.918 84.074  1.00 31.37  ? 193 GLN B CA  1 
ATOM   5208  C C   . GLN B 1 193 ? 142.552 148.566 82.877  1.00 31.37  ? 193 GLN B C   1 
ATOM   5209  O O   . GLN B 1 193 ? 143.733 148.245 83.036  1.00 31.37  ? 193 GLN B O   1 
ATOM   5210  C CB  . GLN B 1 193 ? 140.659 147.815 84.343  1.00 31.37  ? 193 GLN B CB  1 
ATOM   5211  C CG  . GLN B 1 193 ? 141.194 146.407 84.150  1.00 31.37  ? 193 GLN B CG  1 
ATOM   5212  C CD  . GLN B 1 193 ? 142.044 145.923 85.310  1.00 31.37  ? 193 GLN B CD  1 
ATOM   5213  O OE1 . GLN B 1 193 ? 141.777 146.237 86.468  1.00 31.37  ? 193 GLN B OE1 1 
ATOM   5214  N NE2 . GLN B 1 193 ? 143.077 145.154 85.000  1.00 31.37  ? 193 GLN B NE2 1 
ATOM   5215  N N   . THR B 1 194 ? 141.995 148.641 81.663  1.00 33.73  ? 194 THR B N   1 
ATOM   5216  C CA  . THR B 1 194 ? 142.798 148.305 80.487  1.00 33.73  ? 194 THR B CA  1 
ATOM   5217  C C   . THR B 1 194 ? 143.886 149.341 80.223  1.00 33.73  ? 194 THR B C   1 
ATOM   5218  O O   . THR B 1 194 ? 144.946 148.996 79.693  1.00 33.73  ? 194 THR B O   1 
ATOM   5219  C CB  . THR B 1 194 ? 141.918 148.143 79.245  1.00 33.73  ? 194 THR B CB  1 
ATOM   5220  O OG1 . THR B 1 194 ? 141.078 149.292 79.087  1.00 33.73  ? 194 THR B OG1 1 
ATOM   5221  C CG2 . THR B 1 194 ? 141.062 146.897 79.357  1.00 33.73  ? 194 THR B CG2 1 
ATOM   5222  N N   . ASN B 1 195 ? 143.650 150.604 80.583  1.00 35.17  ? 195 ASN B N   1 
ATOM   5223  C CA  . ASN B 1 195 ? 144.649 151.641 80.342  1.00 35.17  ? 195 ASN B CA  1 
ATOM   5224  C C   . ASN B 1 195 ? 145.874 151.460 81.232  1.00 35.17  ? 195 ASN B C   1 
ATOM   5225  O O   . ASN B 1 195 ? 147.009 151.619 80.771  1.00 35.17  ? 195 ASN B O   1 
ATOM   5226  C CB  . ASN B 1 195 ? 144.036 153.022 80.561  1.00 35.17  ? 195 ASN B CB  1 
ATOM   5227  C CG  . ASN B 1 195 ? 143.143 153.454 79.415  1.00 35.17  ? 195 ASN B CG  1 
ATOM   5228  O OD1 . ASN B 1 195 ? 143.175 152.871 78.331  1.00 35.17  ? 195 ASN B OD1 1 
ATOM   5229  N ND2 . ASN B 1 195 ? 142.338 154.483 79.650  1.00 35.17  ? 195 ASN B ND2 1 
ATOM   5230  N N   . LEU B 1 196 ? 145.666 151.141 82.511  1.00 31.49  ? 196 LEU B N   1 
ATOM   5231  C CA  . LEU B 1 196 ? 146.800 150.988 83.419  1.00 31.49  ? 196 LEU B CA  1 
ATOM   5232  C C   . LEU B 1 196 ? 147.440 149.609 83.299  1.00 31.49  ? 196 LEU B C   1 
ATOM   5233  O O   . LEU B 1 196 ? 148.668 149.493 83.267  1.00 31.49  ? 196 LEU B O   1 
ATOM   5234  C CB  . LEU B 1 196 ? 146.364 151.239 84.862  1.00 31.49  ? 196 LEU B CB  1 
ATOM   5235  C CG  . LEU B 1 196 ? 145.732 152.589 85.206  1.00 31.49  ? 196 LEU B CG  1 
ATOM   5236  C CD1 . LEU B 1 196 ? 145.675 152.766 86.713  1.00 31.49  ? 196 LEU B CD1 1 
ATOM   5237  C CD2 . LEU B 1 196 ? 146.487 153.736 84.557  1.00 31.49  ? 196 LEU B CD2 1 
ATOM   5238  N N   . TYR B 1 197 ? 146.624 148.561 83.243  1.00 30.02  ? 197 TYR B N   1 
ATOM   5239  C CA  . TYR B 1 197 ? 147.087 147.183 83.147  1.00 30.02  ? 197 TYR B CA  1 
ATOM   5240  C C   . TYR B 1 197 ? 146.431 146.552 81.929  1.00 30.02  ? 197 TYR B C   1 
ATOM   5241  O O   . TYR B 1 197 ? 145.201 146.534 81.825  1.00 30.02  ? 197 TYR B O   1 
ATOM   5242  C CB  . TYR B 1 197 ? 146.751 146.411 84.424  1.00 30.02  ? 197 TYR B CB  1 
ATOM   5243  C CG  . TYR B 1 197 ? 146.806 147.274 85.667  1.00 30.02  ? 197 TYR B CG  1 
ATOM   5244  C CD1 . TYR B 1 197 ? 148.023 147.635 86.227  1.00 30.02  ? 197 TYR B CD1 1 
ATOM   5245  C CD2 . TYR B 1 197 ? 145.644 147.745 86.265  1.00 30.02  ? 197 TYR B CD2 1 
ATOM   5246  C CE1 . TYR B 1 197 ? 148.083 148.427 87.353  1.00 30.02  ? 197 TYR B CE1 1 
ATOM   5247  C CE2 . TYR B 1 197 ? 145.696 148.540 87.394  1.00 30.02  ? 197 TYR B CE2 1 
ATOM   5248  C CZ  . TYR B 1 197 ? 146.919 148.876 87.933  1.00 30.02  ? 197 TYR B CZ  1 
ATOM   5249  O OH  . TYR B 1 197 ? 146.983 149.666 89.054  1.00 30.02  ? 197 TYR B OH  1 
ATOM   5250  N N   . VAL B 1 198 ? 147.247 146.027 81.016  1.00 31.39  ? 198 VAL B N   1 
ATOM   5251  C CA  . VAL B 1 198 ? 146.741 145.645 79.699  1.00 31.39  ? 198 VAL B CA  1 
ATOM   5252  C C   . VAL B 1 198 ? 145.639 144.598 79.819  1.00 31.39  ? 198 VAL B C   1 
ATOM   5253  O O   . VAL B 1 198 ? 144.637 144.646 79.096  1.00 31.39  ? 198 VAL B O   1 
ATOM   5254  C CB  . VAL B 1 198 ? 147.900 145.157 78.813  1.00 31.39  ? 198 VAL B CB  1 
ATOM   5255  C CG1 . VAL B 1 198 ? 147.382 144.669 77.472  1.00 31.39  ? 198 VAL B CG1 1 
ATOM   5256  C CG2 . VAL B 1 198 ? 148.918 146.270 78.631  1.00 31.39  ? 198 VAL B CG2 1 
ATOM   5257  N N   . GLN B 1 199 ? 145.798 143.648 80.733  1.00 31.78  ? 199 GLN B N   1 
ATOM   5258  C CA  . GLN B 1 199 ? 144.817 142.584 80.888  1.00 31.78  ? 199 GLN B CA  1 
ATOM   5259  C C   . GLN B 1 199 ? 143.497 143.135 81.413  1.00 31.78  ? 199 GLN B C   1 
ATOM   5260  O O   . GLN B 1 199 ? 143.470 144.061 82.227  1.00 31.78  ? 199 GLN B O   1 
ATOM   5261  C CB  . GLN B 1 199 ? 145.353 141.504 81.827  1.00 31.78  ? 199 GLN B CB  1 
ATOM   5262  C CG  . GLN B 1 199 ? 146.367 140.567 81.185  1.00 31.78  ? 199 GLN B CG  1 
ATOM   5263  C CD  . GLN B 1 199 ? 147.673 141.255 80.833  1.00 31.78  ? 199 GLN B CD  1 
ATOM   5264  O OE1 . GLN B 1 199 ? 148.379 141.758 81.704  1.00 31.78  ? 199 GLN B OE1 1 
ATOM   5265  N NE2 . GLN B 1 199 ? 147.992 141.287 79.548  1.00 31.78  ? 199 GLN B NE2 1 
ATOM   5266  N N   . ALA B 1 200 ? 142.393 142.555 80.937  1.00 33.97  ? 200 ALA B N   1 
ATOM   5267  C CA  . ALA B 1 200 ? 141.069 143.026 81.326  1.00 33.97  ? 200 ALA B CA  1 
ATOM   5268  C C   . ALA B 1 200 ? 140.695 142.615 82.742  1.00 33.97  ? 200 ALA B C   1 
ATOM   5269  O O   . ALA B 1 200 ? 139.745 143.170 83.303  1.00 33.97  ? 200 ALA B O   1 
ATOM   5270  C CB  . ALA B 1 200 ? 140.018 142.515 80.342  1.00 33.97  ? 200 ALA B CB  1 
ATOM   5271  N N   . SER B 1 201 ? 141.410 141.660 83.330  1.00 34.58  ? 201 SER B N   1 
ATOM   5272  C CA  . SER B 1 201 ? 141.169 141.236 84.703  1.00 34.58  ? 201 SER B CA  1 
ATOM   5273  C C   . SER B 1 201 ? 142.499 140.856 85.335  1.00 34.58  ? 201 SER B C   1 
ATOM   5274  O O   . SER B 1 201 ? 143.119 139.869 84.930  1.00 34.58  ? 201 SER B O   1 
ATOM   5275  C CB  . SER B 1 201 ? 140.190 140.061 84.756  1.00 34.58  ? 201 SER B CB  1 
ATOM   5276  O OG  . SER B 1 201 ? 140.253 139.400 86.006  1.00 34.58  ? 201 SER B OG  1 
ATOM   5277  N N   . GLY B 1 202 ? 142.932 141.635 86.324  1.00 30.95  ? 202 GLY B N   1 
ATOM   5278  C CA  . GLY B 1 202 ? 144.192 141.388 86.989  1.00 30.95  ? 202 GLY B CA  1 
ATOM   5279  C C   . GLY B 1 202 ? 144.088 140.332 88.071  1.00 30.95  ? 202 GLY B C   1 
ATOM   5280  O O   . GLY B 1 202 ? 143.018 139.818 88.393  1.00 30.95  ? 202 GLY B O   1 
ATOM   5281  N N   . ARG B 1 203 ? 145.243 140.013 88.652  1.00 29.46  ? 203 ARG B N   1 
ATOM   5282  C CA  . ARG B 1 203 ? 145.327 138.972 89.665  1.00 29.46  ? 203 ARG B CA  1 
ATOM   5283  C C   . ARG B 1 203 ? 146.658 139.092 90.393  1.00 29.46  ? 203 ARG B C   1 
ATOM   5284  O O   . ARG B 1 203 ? 147.699 139.323 89.759  1.00 29.46  ? 203 ARG B O   1 
ATOM   5285  C CB  . ARG B 1 203 ? 145.186 137.580 89.036  1.00 29.46  ? 203 ARG B CB  1 
ATOM   5286  C CG  . ARG B 1 203 ? 145.350 136.434 90.004  1.00 29.46  ? 203 ARG B CG  1 
ATOM   5287  C CD  . ARG B 1 203 ? 145.456 135.104 89.274  1.00 29.46  ? 203 ARG B CD  1 
ATOM   5288  N NE  . ARG B 1 203 ? 146.439 135.129 88.197  1.00 29.46  ? 203 ARG B NE  1 
ATOM   5289  C CZ  . ARG B 1 203 ? 147.754 135.093 88.373  1.00 29.46  ? 203 ARG B CZ  1 
ATOM   5290  N NH1 . ARG B 1 203 ? 148.291 135.050 89.581  1.00 29.46  ? 203 ARG B NH1 1 
ATOM   5291  N NH2 . ARG B 1 203 ? 148.550 135.101 87.309  1.00 29.46  ? 203 ARG B NH2 1 
ATOM   5292  N N   . VAL B 1 204 ? 146.614 138.928 91.721  1.00 26.80  ? 204 VAL B N   1 
ATOM   5293  C CA  . VAL B 1 204 ? 147.804 138.969 92.569  1.00 26.80  ? 204 VAL B CA  1 
ATOM   5294  C C   . VAL B 1 204 ? 147.815 137.741 93.473  1.00 26.80  ? 204 VAL B C   1 
ATOM   5295  O O   . VAL B 1 204 ? 146.846 137.494 94.195  1.00 26.80  ? 204 VAL B O   1 
ATOM   5296  C CB  . VAL B 1 204 ? 147.856 140.257 93.417  1.00 26.80  ? 204 VAL B CB  1 
ATOM   5297  C CG1 . VAL B 1 204 ? 149.068 140.249 94.333  1.00 26.80  ? 204 VAL B CG1 1 
ATOM   5298  C CG2 . VAL B 1 204 ? 147.867 141.487 92.527  1.00 26.80  ? 204 VAL B CG2 1 
ATOM   5299  N N   . THR B 1 205 ? 148.917 136.989 93.456  1.00 27.61  ? 205 THR B N   1 
ATOM   5300  C CA  . THR B 1 205 ? 149.094 135.823 94.314  1.00 27.61  ? 205 THR B CA  1 
ATOM   5301  C C   . THR B 1 205 ? 150.394 135.965 95.092  1.00 27.61  ? 205 THR B C   1 
ATOM   5302  O O   . THR B 1 205 ? 151.453 136.194 94.501  1.00 27.61  ? 205 THR B O   1 
ATOM   5303  C CB  . THR B 1 205 ? 149.114 134.521 93.497  1.00 27.61  ? 205 THR B CB  1 
ATOM   5304  O OG1 . THR B 1 205 ? 147.962 134.462 92.649  1.00 27.61  ? 205 THR B OG1 1 
ATOM   5305  C CG2 . THR B 1 205 ? 149.121 133.309 94.413  1.00 27.61  ? 205 THR B CG2 1 
ATOM   5306  N N   . VAL B 1 206 ? 150.312 135.824 96.412  1.00 25.89  ? 206 VAL B N   1 
ATOM   5307  C CA  . VAL B 1 206 ? 151.466 135.913 97.299  1.00 25.89  ? 206 VAL B CA  1 
ATOM   5308  C C   . VAL B 1 206 ? 151.496 134.656 98.155  1.00 25.89  ? 206 VAL B C   1 
ATOM   5309  O O   . VAL B 1 206 ? 150.503 134.332 98.815  1.00 25.89  ? 206 VAL B O   1 
ATOM   5310  C CB  . VAL B 1 206 ? 151.407 137.174 98.184  1.00 25.89  ? 206 VAL B CB  1 
ATOM   5311  C CG1 . VAL B 1 206 ? 152.608 137.237 99.109  1.00 25.89  ? 206 VAL B CG1 1 
ATOM   5312  C CG2 . VAL B 1 206 ? 151.320 138.429 97.326  1.00 25.89  ? 206 VAL B CG2 1 
ATOM   5313  N N   . SER B 1 207 ? 152.627 133.951 98.161  1.00 29.05  ? 207 SER B N   1 
ATOM   5314  C CA  . SER B 1 207 ? 152.635 132.655 98.826  1.00 29.05  ? 207 SER B CA  1 
ATOM   5315  C C   . SER B 1 207 ? 153.989 132.343 99.449  1.00 29.05  ? 207 SER B C   1 
ATOM   5316  O O   . SER B 1 207 ? 155.029 132.851 99.021  1.00 29.05  ? 207 SER B O   1 
ATOM   5317  C CB  . SER B 1 207 ? 152.247 131.538 97.852  1.00 29.05  ? 207 SER B CB  1 
ATOM   5318  O OG  . SER B 1 207 ? 153.067 131.567 96.701  1.00 29.05  ? 207 SER B OG  1 
ATOM   5319  N N   . THR B 1 208 ? 153.951 131.501 100.476 1.00 31.55  ? 208 THR B N   1 
ATOM   5320  C CA  . THR B 1 208 ? 155.112 130.843 101.061 1.00 31.55  ? 208 THR B CA  1 
ATOM   5321  C C   . THR B 1 208 ? 154.919 129.330 100.946 1.00 31.55  ? 208 THR B C   1 
ATOM   5322  O O   . THR B 1 208 ? 153.984 128.849 100.300 1.00 31.55  ? 208 THR B O   1 
ATOM   5323  C CB  . THR B 1 208 ? 155.323 131.268 102.518 1.00 31.55  ? 208 THR B CB  1 
ATOM   5324  O OG1 . THR B 1 208 ? 154.194 130.875 103.305 1.00 31.55  ? 208 THR B OG1 1 
ATOM   5325  C CG2 . THR B 1 208 ? 155.515 132.774 102.627 1.00 31.55  ? 208 THR B CG2 1 
ATOM   5326  N N   . ARG B 1 209 ? 155.816 128.573 101.578 1.00 33.58  ? 209 ARG B N   1 
ATOM   5327  C CA  . ARG B 1 209 ? 155.678 127.121 101.582 1.00 33.58  ? 209 ARG B CA  1 
ATOM   5328  C C   . ARG B 1 209 ? 154.502 126.650 102.428 1.00 33.58  ? 209 ARG B C   1 
ATOM   5329  O O   . ARG B 1 209 ? 154.019 125.533 102.222 1.00 33.58  ? 209 ARG B O   1 
ATOM   5330  C CB  . ARG B 1 209 ? 156.966 126.465 102.078 1.00 33.58  ? 209 ARG B CB  1 
ATOM   5331  C CG  . ARG B 1 209 ? 158.145 126.623 101.137 1.00 33.58  ? 209 ARG B CG  1 
ATOM   5332  C CD  . ARG B 1 209 ? 159.071 125.424 101.199 1.00 33.58  ? 209 ARG B CD  1 
ATOM   5333  N NE  . ARG B 1 209 ? 160.303 125.647 100.453 1.00 33.58  ? 209 ARG B NE  1 
ATOM   5334  C CZ  . ARG B 1 209 ? 161.395 126.206 100.955 1.00 33.58  ? 209 ARG B CZ  1 
ATOM   5335  N NH1 . ARG B 1 209 ? 161.454 126.595 102.217 1.00 33.58  ? 209 ARG B NH1 1 
ATOM   5336  N NH2 . ARG B 1 209 ? 162.453 126.380 100.170 1.00 33.58  ? 209 ARG B NH2 1 
ATOM   5337  N N   . ARG B 1 210 ? 154.023 127.470 103.361 1.00 36.51  ? 210 ARG B N   1 
ATOM   5338  C CA  . ARG B 1 210 ? 152.959 127.059 104.265 1.00 36.51  ? 210 ARG B CA  1 
ATOM   5339  C C   . ARG B 1 210 ? 151.690 127.895 104.161 1.00 36.51  ? 210 ARG B C   1 
ATOM   5340  O O   . ARG B 1 210 ? 150.753 127.656 104.931 1.00 36.51  ? 210 ARG B O   1 
ATOM   5341  C CB  . ARG B 1 210 ? 153.463 127.081 105.714 1.00 36.51  ? 210 ARG B CB  1 
ATOM   5342  C CG  . ARG B 1 210 ? 153.857 128.455 106.222 1.00 36.51  ? 210 ARG B CG  1 
ATOM   5343  C CD  . ARG B 1 210 ? 154.897 128.350 107.323 1.00 36.51  ? 210 ARG B CD  1 
ATOM   5344  N NE  . ARG B 1 210 ? 156.098 127.658 106.870 1.00 36.51  ? 210 ARG B NE  1 
ATOM   5345  C CZ  . ARG B 1 210 ? 157.205 127.525 107.588 1.00 36.51  ? 210 ARG B CZ  1 
ATOM   5346  N NH1 . ARG B 1 210 ? 157.300 128.021 108.810 1.00 36.51  ? 210 ARG B NH1 1 
ATOM   5347  N NH2 . ARG B 1 210 ? 158.243 126.879 107.065 1.00 36.51  ? 210 ARG B NH2 1 
ATOM   5348  N N   . SER B 1 211 ? 151.618 128.855 103.242 1.00 32.72  ? 211 SER B N   1 
ATOM   5349  C CA  . SER B 1 211 ? 150.438 129.704 103.142 1.00 32.72  ? 211 SER B CA  1 
ATOM   5350  C C   . SER B 1 211 ? 150.366 130.310 101.749 1.00 32.72  ? 211 SER B C   1 
ATOM   5351  O O   . SER B 1 211 ? 151.351 130.325 101.008 1.00 32.72  ? 211 SER B O   1 
ATOM   5352  C CB  . SER B 1 211 ? 150.450 130.803 104.208 1.00 32.72  ? 211 SER B CB  1 
ATOM   5353  O OG  . SER B 1 211 ? 151.252 131.896 103.801 1.00 32.72  ? 211 SER B OG  1 
ATOM   5354  N N   . GLN B 1 212 ? 149.181 130.813 101.405 1.00 29.53  ? 212 GLN B N   1 
ATOM   5355  C CA  . GLN B 1 212 ? 148.955 131.443 100.112 1.00 29.53  ? 212 GLN B CA  1 
ATOM   5356  C C   . GLN B 1 212 ? 147.761 132.382 100.210 1.00 29.53  ? 212 GLN B C   1 
ATOM   5357  O O   . GLN B 1 212 ? 146.828 132.141 100.978 1.00 29.53  ? 212 GLN B O   1 
ATOM   5358  C CB  . GLN B 1 212 ? 148.721 130.401 99.014  1.00 29.53  ? 212 GLN B CB  1 
ATOM   5359  C CG  . GLN B 1 212 ? 147.793 129.272 99.422  1.00 29.53  ? 212 GLN B CG  1 
ATOM   5360  C CD  . GLN B 1 212 ? 146.550 129.200 98.563  1.00 29.53  ? 212 GLN B CD  1 
ATOM   5361  O OE1 . GLN B 1 212 ? 146.077 130.211 98.049  1.00 29.53  ? 212 GLN B OE1 1 
ATOM   5362  N NE2 . GLN B 1 212 ? 146.015 127.998 98.399  1.00 29.53  ? 212 GLN B NE2 1 
ATOM   5363  N N   . GLN B 1 213 ? 147.807 133.458 99.422  1.00 28.15  ? 213 GLN B N   1 
ATOM   5364  C CA  . GLN B 1 213 ? 146.720 134.425 99.316  1.00 28.15  ? 213 GLN B CA  1 
ATOM   5365  C C   . GLN B 1 213 ? 146.596 134.858 97.863  1.00 28.15  ? 213 GLN B C   1 
ATOM   5366  O O   . GLN B 1 213 ? 147.605 135.150 97.216  1.00 28.15  ? 213 GLN B O   1 
ATOM   5367  C CB  . GLN B 1 213 ? 146.964 135.654 100.205 1.00 28.15  ? 213 GLN B CB  1 
ATOM   5368  C CG  . GLN B 1 213 ? 147.050 135.369 101.695 1.00 28.15  ? 213 GLN B CG  1 
ATOM   5369  C CD  . GLN B 1 213 ? 147.628 136.531 102.487 1.00 28.15  ? 213 GLN B CD  1 
ATOM   5370  O OE1 . GLN B 1 213 ? 148.823 136.565 102.778 1.00 28.15  ? 213 GLN B OE1 1 
ATOM   5371  N NE2 . GLN B 1 213 ? 146.780 137.485 102.844 1.00 28.15  ? 213 GLN B NE2 1 
ATOM   5372  N N   . THR B 1 214 ? 145.368 134.901 97.348  1.00 28.59  ? 214 THR B N   1 
ATOM   5373  C CA  . THR B 1 214 ? 145.115 135.364 95.988  1.00 28.59  ? 214 THR B CA  1 
ATOM   5374  C C   . THR B 1 214 ? 143.991 136.388 96.002  1.00 28.59  ? 214 THR B C   1 
ATOM   5375  O O   . THR B 1 214 ? 142.957 136.173 96.641  1.00 28.59  ? 214 THR B O   1 
ATOM   5376  C CB  . THR B 1 214 ? 144.758 134.206 95.049  1.00 28.59  ? 214 THR B CB  1 
ATOM   5377  O OG1 . THR B 1 214 ? 145.855 133.289 94.978  1.00 28.59  ? 214 THR B OG1 1 
ATOM   5378  C CG2 . THR B 1 214 ? 144.461 134.724 93.649  1.00 28.59  ? 214 THR B CG2 1 
ATOM   5379  N N   . ILE B 1 215 ? 144.197 137.495 95.292  1.00 27.60  ? 215 ILE B N   1 
ATOM   5380  C CA  . ILE B 1 215 ? 143.260 138.609 95.256  1.00 27.60  ? 215 ILE B CA  1 
ATOM   5381  C C   . ILE B 1 215 ? 142.943 138.944 93.805  1.00 27.60  ? 215 ILE B C   1 
ATOM   5382  O O   . ILE B 1 215 ? 143.855 139.081 92.974  1.00 27.60  ? 215 ILE B O   1 
ATOM   5383  C CB  . ILE B 1 215 ? 143.811 139.849 95.989  1.00 27.60  ? 215 ILE B CB  1 
ATOM   5384  C CG1 . ILE B 1 215 ? 144.401 139.463 97.348  1.00 27.60  ? 215 ILE B CG1 1 
ATOM   5385  C CG2 . ILE B 1 215 ? 142.724 140.899 96.155  1.00 27.60  ? 215 ILE B CG2 1 
ATOM   5386  C CD1 . ILE B 1 215 ? 143.373 139.096 98.385  1.00 27.60  ? 215 ILE B CD1 1 
ATOM   5387  N N   . VAL B 1 216 ? 141.657 139.063 93.509  1.00 29.14  ? 216 VAL B N   1 
ATOM   5388  C CA  . VAL B 1 216 ? 141.146 139.561 92.233  1.00 29.14  ? 216 VAL B CA  1 
ATOM   5389  C C   . VAL B 1 216 ? 140.565 140.948 92.476  1.00 29.14  ? 216 VAL B C   1 
ATOM   5390  O O   . VAL B 1 216 ? 139.708 141.100 93.354  1.00 29.14  ? 216 VAL B O   1 
ATOM   5391  C CB  . VAL B 1 216 ? 140.078 138.624 91.636  1.00 29.14  ? 216 VAL B CB  1 
ATOM   5392  C CG1 . VAL B 1 216 ? 139.511 139.208 90.349  1.00 29.14  ? 216 VAL B CG1 1 
ATOM   5393  C CG2 . VAL B 1 216 ? 140.655 137.242 91.385  1.00 29.14  ? 216 VAL B CG2 1 
ATOM   5394  N N   . PRO B 1 217 ? 141.002 141.972 91.749  1.00 28.25  ? 217 PRO B N   1 
ATOM   5395  C CA  . PRO B 1 217 ? 140.530 143.335 92.023  1.00 28.25  ? 217 PRO B CA  1 
ATOM   5396  C C   . PRO B 1 217 ? 139.063 143.530 91.663  1.00 28.25  ? 217 PRO B C   1 
ATOM   5397  O O   . PRO B 1 217 ? 138.496 142.835 90.819  1.00 28.25  ? 217 PRO B O   1 
ATOM   5398  C CB  . PRO B 1 217 ? 141.431 144.207 91.143  1.00 28.25  ? 217 PRO B CB  1 
ATOM   5399  C CG  . PRO B 1 217 ? 141.950 143.294 90.097  1.00 28.25  ? 217 PRO B CG  1 
ATOM   5400  C CD  . PRO B 1 217 ? 142.031 141.935 90.699  1.00 28.25  ? 217 PRO B CD  1 
ATOM   5401  N N   . ASN B 1 218 ? 138.453 144.509 92.328  1.00 30.04  ? 218 ASN B N   1 
ATOM   5402  C CA  . ASN B 1 218 ? 137.071 144.902 92.090  1.00 30.04  ? 218 ASN B CA  1 
ATOM   5403  C C   . ASN B 1 218 ? 137.025 146.200 91.293  1.00 30.04  ? 218 ASN B C   1 
ATOM   5404  O O   . ASN B 1 218 ? 137.879 147.073 91.464  1.00 30.04  ? 218 ASN B O   1 
ATOM   5405  C CB  . ASN B 1 218 ? 136.321 145.084 93.410  1.00 30.04  ? 218 ASN B CB  1 
ATOM   5406  C CG  . ASN B 1 218 ? 136.692 144.041 94.447  1.00 30.04  ? 218 ASN B CG  1 
ATOM   5407  O OD1 . ASN B 1 218 ? 136.827 142.858 94.137  1.00 30.04  ? 218 ASN B OD1 1 
ATOM   5408  N ND2 . ASN B 1 218 ? 136.850 144.477 95.689  1.00 30.04  ? 218 ASN B ND2 1 
ATOM   5409  N N   . ILE B 1 219 ? 136.024 146.326 90.426  1.00 30.45  ? 219 ILE B N   1 
ATOM   5410  C CA  . ILE B 1 219 ? 135.877 147.486 89.554  1.00 30.45  ? 219 ILE B CA  1 
ATOM   5411  C C   . ILE B 1 219 ? 134.535 148.149 89.838  1.00 30.45  ? 219 ILE B C   1 
ATOM   5412  O O   . ILE B 1 219 ? 133.524 147.466 90.026  1.00 30.45  ? 219 ILE B O   1 
ATOM   5413  C CB  . ILE B 1 219 ? 136.003 147.087 88.067  1.00 30.45  ? 219 ILE B CB  1 
ATOM   5414  C CG1 . ILE B 1 219 ? 137.462 146.779 87.730  1.00 30.45  ? 219 ILE B CG1 1 
ATOM   5415  C CG2 . ILE B 1 219 ? 135.490 148.187 87.156  1.00 30.45  ? 219 ILE B CG2 1 
ATOM   5416  C CD1 . ILE B 1 219 ? 137.644 145.945 86.489  1.00 30.45  ? 219 ILE B CD1 1 
ATOM   5417  N N   . GLY B 1 220 ? 134.532 149.473 89.895  1.00 29.16  ? 220 GLY B N   1 
ATOM   5418  C CA  . GLY B 1 220 ? 133.310 150.225 90.100  1.00 29.16  ? 220 GLY B CA  1 
ATOM   5419  C C   . GLY B 1 220 ? 133.589 151.620 90.604  1.00 29.16  ? 220 GLY B C   1 
ATOM   5420  O O   . GLY B 1 220 ? 134.632 151.908 91.191  1.00 29.16  ? 220 GLY B O   1 
ATOM   5421  N N   . SER B 1 221 ? 132.626 152.508 90.364  1.00 29.15  ? 221 SER B N   1 
ATOM   5422  C CA  . SER B 1 221 ? 132.737 153.891 90.807  1.00 29.15  ? 221 SER B CA  1 
ATOM   5423  C C   . SER B 1 221 ? 132.496 154.004 92.306  1.00 29.15  ? 221 SER B C   1 
ATOM   5424  O O   . SER B 1 221 ? 131.649 153.307 92.870  1.00 29.15  ? 221 SER B O   1 
ATOM   5425  C CB  . SER B 1 221 ? 131.746 154.779 90.056  1.00 29.15  ? 221 SER B CB  1 
ATOM   5426  O OG  . SER B 1 221 ? 132.055 154.842 88.677  1.00 29.15  ? 221 SER B OG  1 
ATOM   5427  N N   . ARG B 1 222 ? 133.242 154.894 92.945  1.00 28.11  ? 222 ARG B N   1 
ATOM   5428  C CA  . ARG B 1 222 ? 133.170 155.145 94.375  1.00 28.11  ? 222 ARG B CA  1 
ATOM   5429  C C   . ARG B 1 222 ? 133.176 156.648 94.602  1.00 28.11  ? 222 ARG B C   1 
ATOM   5430  O O   . ARG B 1 222 ? 133.545 157.412 93.703  1.00 28.11  ? 222 ARG B O   1 
ATOM   5431  C CB  . ARG B 1 222 ? 134.341 154.482 95.113  1.00 28.11  ? 222 ARG B CB  1 
ATOM   5432  C CG  . ARG B 1 222 ? 134.238 152.975 95.197  1.00 28.11  ? 222 ARG B CG  1 
ATOM   5433  C CD  . ARG B 1 222 ? 135.594 152.321 95.125  1.00 28.11  ? 222 ARG B CD  1 
ATOM   5434  N NE  . ARG B 1 222 ? 135.513 150.920 94.739  1.00 28.11  ? 222 ARG B NE  1 
ATOM   5435  C CZ  . ARG B 1 222 ? 136.201 150.380 93.744  1.00 28.11  ? 222 ARG B CZ  1 
ATOM   5436  N NH1 . ARG B 1 222 ? 137.020 151.102 92.999  1.00 28.11  ? 222 ARG B NH1 1 
ATOM   5437  N NH2 . ARG B 1 222 ? 136.063 149.083 93.489  1.00 28.11  ? 222 ARG B NH2 1 
ATOM   5438  N N   . PRO B 1 223 ? 132.741 157.108 95.779  1.00 29.27  ? 223 PRO B N   1 
ATOM   5439  C CA  . PRO B 1 223 ? 132.773 158.551 96.053  1.00 29.27  ? 223 PRO B CA  1 
ATOM   5440  C C   . PRO B 1 223 ? 134.190 159.102 95.999  1.00 29.27  ? 223 PRO B C   1 
ATOM   5441  O O   . PRO B 1 223 ? 135.150 158.444 96.403  1.00 29.27  ? 223 PRO B O   1 
ATOM   5442  C CB  . PRO B 1 223 ? 132.181 158.663 97.463  1.00 29.27  ? 223 PRO B CB  1 
ATOM   5443  C CG  . PRO B 1 223 ? 131.451 157.400 97.687  1.00 29.27  ? 223 PRO B CG  1 
ATOM   5444  C CD  . PRO B 1 223 ? 132.152 156.352 96.897  1.00 29.27  ? 223 PRO B CD  1 
ATOM   5445  N N   . TRP B 1 224 ? 134.311 160.325 95.488  1.00 30.49  ? 224 TRP B N   1 
ATOM   5446  C CA  . TRP B 1 224 ? 135.611 160.974 95.385  1.00 30.49  ? 224 TRP B CA  1 
ATOM   5447  C C   . TRP B 1 224 ? 136.217 161.197 96.763  1.00 30.49  ? 224 TRP B C   1 
ATOM   5448  O O   . TRP B 1 224 ? 135.561 161.716 97.669  1.00 30.49  ? 224 TRP B O   1 
ATOM   5449  C CB  . TRP B 1 224 ? 135.477 162.310 94.657  1.00 30.49  ? 224 TRP B CB  1 
ATOM   5450  C CG  . TRP B 1 224 ? 135.634 162.225 93.178  1.00 30.49  ? 224 TRP B CG  1 
ATOM   5451  C CD1 . TRP B 1 224 ? 135.348 161.157 92.382  1.00 30.49  ? 224 TRP B CD1 1 
ATOM   5452  C CD2 . TRP B 1 224 ? 136.109 163.258 92.311  1.00 30.49  ? 224 TRP B CD2 1 
ATOM   5453  N NE1 . TRP B 1 224 ? 135.619 161.459 91.072  1.00 30.49  ? 224 TRP B NE1 1 
ATOM   5454  C CE2 . TRP B 1 224 ? 136.088 162.744 91.002  1.00 30.49  ? 224 TRP B CE2 1 
ATOM   5455  C CE3 . TRP B 1 224 ? 136.553 164.567 92.515  1.00 30.49  ? 224 TRP B CE3 1 
ATOM   5456  C CZ2 . TRP B 1 224 ? 136.496 163.492 89.901  1.00 30.49  ? 224 TRP B CZ2 1 
ATOM   5457  C CZ3 . TRP B 1 224 ? 136.953 165.307 91.421  1.00 30.49  ? 224 TRP B CZ3 1 
ATOM   5458  C CH2 . TRP B 1 224 ? 136.922 164.769 90.131  1.00 30.49  ? 224 TRP B CH2 1 
ATOM   5459  N N   . VAL B 1 225 ? 137.476 160.798 96.920  1.00 27.56  ? 225 VAL B N   1 
ATOM   5460  C CA  . VAL B 1 225 ? 138.271 161.119 98.100  1.00 27.56  ? 225 VAL B CA  1 
ATOM   5461  C C   . VAL B 1 225 ? 139.566 161.737 97.597  1.00 27.56  ? 225 VAL B C   1 
ATOM   5462  O O   . VAL B 1 225 ? 140.391 161.045 96.989  1.00 27.56  ? 225 VAL B O   1 
ATOM   5463  C CB  . VAL B 1 225 ? 138.551 159.892 98.979  1.00 27.56  ? 225 VAL B CB  1 
ATOM   5464  C CG1 . VAL B 1 225 ? 139.410 160.284 100.166 1.00 27.56  ? 225 VAL B CG1 1 
ATOM   5465  C CG2 . VAL B 1 225 ? 137.254 159.267 99.452  1.00 27.56  ? 225 VAL B CG2 1 
ATOM   5466  N N   . ARG B 1 226 ? 139.743 163.034 97.847  1.00 27.51  ? 226 ARG B N   1 
ATOM   5467  C CA  . ARG B 1 226 ? 140.891 163.794 97.350  1.00 27.51  ? 226 ARG B CA  1 
ATOM   5468  C C   . ARG B 1 226 ? 141.046 163.640 95.839  1.00 27.51  ? 226 ARG B C   1 
ATOM   5469  O O   . ARG B 1 226 ? 142.152 163.512 95.312  1.00 27.51  ? 226 ARG B O   1 
ATOM   5470  C CB  . ARG B 1 226 ? 142.176 163.401 98.085  1.00 27.51  ? 226 ARG B CB  1 
ATOM   5471  C CG  . ARG B 1 226 ? 142.210 163.864 99.536  1.00 27.51  ? 226 ARG B CG  1 
ATOM   5472  C CD  . ARG B 1 226 ? 143.518 163.513 100.236 1.00 27.51  ? 226 ARG B CD  1 
ATOM   5473  N NE  . ARG B 1 226 ? 143.562 162.127 100.686 1.00 27.51  ? 226 ARG B NE  1 
ATOM   5474  C CZ  . ARG B 1 226 ? 142.850 161.635 101.690 1.00 27.51  ? 226 ARG B CZ  1 
ATOM   5475  N NH1 . ARG B 1 226 ? 142.024 162.394 102.389 1.00 27.51  ? 226 ARG B NH1 1 
ATOM   5476  N NH2 . ARG B 1 226 ? 142.968 160.348 102.000 1.00 27.51  ? 226 ARG B NH2 1 
ATOM   5477  N N   . GLY B 1 227 ? 139.915 163.652 95.134  1.00 27.99  ? 227 GLY B N   1 
ATOM   5478  C CA  . GLY B 1 227 ? 139.898 163.628 93.688  1.00 27.99  ? 227 GLY B CA  1 
ATOM   5479  C C   . GLY B 1 227 ? 139.854 162.262 93.035  1.00 27.99  ? 227 GLY B C   1 
ATOM   5480  O O   . GLY B 1 227 ? 139.763 162.193 91.805  1.00 27.99  ? 227 GLY B O   1 
ATOM   5481  N N   . GLN B 1 228 ? 139.903 161.175 93.803  1.00 28.32  ? 228 GLN B N   1 
ATOM   5482  C CA  . GLN B 1 228 ? 140.049 159.837 93.245  1.00 28.32  ? 228 GLN B CA  1 
ATOM   5483  C C   . GLN B 1 228 ? 138.871 158.950 93.620  1.00 28.32  ? 228 GLN B C   1 
ATOM   5484  O O   . GLN B 1 228 ? 138.413 158.958 94.765  1.00 28.32  ? 228 GLN B O   1 
ATOM   5485  C CB  . GLN B 1 228 ? 141.352 159.180 93.719  1.00 28.32  ? 228 GLN B CB  1 
ATOM   5486  C CG  . GLN B 1 228 ? 142.581 160.047 93.552  1.00 28.32  ? 228 GLN B CG  1 
ATOM   5487  C CD  . GLN B 1 228 ? 142.818 160.443 92.112  1.00 28.32  ? 228 GLN B CD  1 
ATOM   5488  O OE1 . GLN B 1 228 ? 142.674 159.632 91.201  1.00 28.32  ? 228 GLN B OE1 1 
ATOM   5489  N NE2 . GLN B 1 228 ? 143.189 161.697 91.899  1.00 28.32  ? 228 GLN B NE2 1 
ATOM   5490  N N   . SER B 1 229 ? 138.402 158.163 92.651  1.00 28.48  ? 229 SER B N   1 
ATOM   5491  C CA  . SER B 1 229 ? 137.351 157.183 92.890  1.00 28.48  ? 229 SER B CA  1 
ATOM   5492  C C   . SER B 1 229 ? 137.867 155.751 92.976  1.00 28.48  ? 229 SER B C   1 
ATOM   5493  O O   . SER B 1 229 ? 137.094 154.858 93.334  1.00 28.48  ? 229 SER B O   1 
ATOM   5494  C CB  . SER B 1 229 ? 136.277 157.278 91.800  1.00 28.48  ? 229 SER B CB  1 
ATOM   5495  O OG  . SER B 1 229 ? 136.850 157.219 90.509  1.00 28.48  ? 229 SER B OG  1 
ATOM   5496  N N   . GLY B 1 230 ? 139.145 155.509 92.664  1.00 25.00  ? 230 GLY B N   1 
ATOM   5497  C CA  . GLY B 1 230 ? 139.730 154.200 92.865  1.00 25.00  ? 230 GLY B CA  1 
ATOM   5498  C C   . GLY B 1 230 ? 140.188 153.989 94.298  1.00 25.00  ? 230 GLY B C   1 
ATOM   5499  O O   . GLY B 1 230 ? 140.248 154.915 95.103  1.00 25.00  ? 230 GLY B O   1 
ATOM   5500  N N   . ARG B 1 231 ? 140.520 152.740 94.624  1.00 24.39  ? 231 ARG B N   1 
ATOM   5501  C CA  . ARG B 1 231 ? 140.922 152.413 95.989  1.00 24.39  ? 231 ARG B CA  1 
ATOM   5502  C C   . ARG B 1 231 ? 142.105 151.455 95.974  1.00 24.39  ? 231 ARG B C   1 
ATOM   5503  O O   . ARG B 1 231 ? 142.493 150.927 94.933  1.00 24.39  ? 231 ARG B O   1 
ATOM   5504  C CB  . ARG B 1 231 ? 139.763 151.809 96.797  1.00 24.39  ? 231 ARG B CB  1 
ATOM   5505  C CG  . ARG B 1 231 ? 138.551 152.714 96.961  1.00 24.39  ? 231 ARG B CG  1 
ATOM   5506  C CD  . ARG B 1 231 ? 138.824 153.865 97.914  1.00 24.39  ? 231 ARG B CD  1 
ATOM   5507  N NE  . ARG B 1 231 ? 137.601 154.553 98.311  1.00 24.39  ? 231 ARG B NE  1 
ATOM   5508  C CZ  . ARG B 1 231 ? 137.143 155.665 97.751  1.00 24.39  ? 231 ARG B CZ  1 
ATOM   5509  N NH1 . ARG B 1 231 ? 137.784 156.256 96.758  1.00 24.39  ? 231 ARG B NH1 1 
ATOM   5510  N NH2 . ARG B 1 231 ? 136.013 156.199 98.202  1.00 24.39  ? 231 ARG B NH2 1 
ATOM   5511  N N   . ILE B 1 232 ? 142.691 151.245 97.151  1.00 22.12  ? 232 ILE B N   1 
ATOM   5512  C CA  . ILE B 1 232 ? 143.751 150.264 97.350  1.00 22.12  ? 232 ILE B CA  1 
ATOM   5513  C C   . ILE B 1 232 ? 143.436 149.452 98.600  1.00 22.12  ? 232 ILE B C   1 
ATOM   5514  O O   . ILE B 1 232 ? 142.984 150.000 99.609  1.00 22.12  ? 232 ILE B O   1 
ATOM   5515  C CB  . ILE B 1 232 ? 145.137 150.941 97.450  1.00 22.12  ? 232 ILE B CB  1 
ATOM   5516  C CG1 . ILE B 1 232 ? 145.642 151.309 96.056  1.00 22.12  ? 232 ILE B CG1 1 
ATOM   5517  C CG2 . ILE B 1 232 ? 146.146 150.045 98.148  1.00 22.12  ? 232 ILE B CG2 1 
ATOM   5518  C CD1 . ILE B 1 232 ? 146.873 152.166 96.059  1.00 22.12  ? 232 ILE B CD1 1 
ATOM   5519  N N   . SER B 1 233 ? 143.651 148.141 98.524  1.00 21.76  ? 233 SER B N   1 
ATOM   5520  C CA  . SER B 1 233 ? 143.484 147.234 99.652  1.00 21.76  ? 233 SER B CA  1 
ATOM   5521  C C   . SER B 1 233 ? 144.846 146.729 100.110 1.00 21.76  ? 233 SER B C   1 
ATOM   5522  O O   . SER B 1 233 ? 145.703 146.404 99.284  1.00 21.76  ? 233 SER B O   1 
ATOM   5523  C CB  . SER B 1 233 ? 142.588 146.051 99.279  1.00 21.76  ? 233 SER B CB  1 
ATOM   5524  O OG  . SER B 1 233 ? 141.227 146.339 99.527  1.00 21.76  ? 233 SER B OG  1 
ATOM   5525  N N   . ILE B 1 234 ? 145.032 146.641 101.426 1.00 20.49  ? 234 ILE B N   1 
ATOM   5526  C CA  . ILE B 1 234 ? 146.325 146.350 102.038 1.00 20.49  ? 234 ILE B CA  1 
ATOM   5527  C C   . ILE B 1 234 ? 146.302 144.958 102.658 1.00 20.49  ? 234 ILE B C   1 
ATOM   5528  O O   . ILE B 1 234 ? 145.327 144.573 103.312 1.00 20.49  ? 234 ILE B O   1 
ATOM   5529  C CB  . ILE B 1 234 ? 146.689 147.419 103.090 1.00 20.49  ? 234 ILE B CB  1 
ATOM   5530  C CG1 . ILE B 1 234 ? 146.855 148.786 102.425 1.00 20.49  ? 234 ILE B CG1 1 
ATOM   5531  C CG2 . ILE B 1 234 ? 147.954 147.042 103.841 1.00 20.49  ? 234 ILE B CG2 1 
ATOM   5532  C CD1 . ILE B 1 234 ? 147.972 148.840 101.420 1.00 20.49  ? 234 ILE B CD1 1 
ATOM   5533  N N   . TYR B 1 235 ? 147.384 144.206 102.450 1.00 20.99  ? 235 TYR B N   1 
ATOM   5534  C CA  . TYR B 1 235 ? 147.537 142.853 102.967 1.00 20.99  ? 235 TYR B CA  1 
ATOM   5535  C C   . TYR B 1 235 ? 148.953 142.678 103.504 1.00 20.99  ? 235 TYR B C   1 
ATOM   5536  O O   . TYR B 1 235 ? 149.856 143.457 103.188 1.00 20.99  ? 235 TYR B O   1 
ATOM   5537  C CB  . TYR B 1 235 ? 147.242 141.805 101.885 1.00 20.99  ? 235 TYR B CB  1 
ATOM   5538  C CG  . TYR B 1 235 ? 145.838 141.865 101.333 1.00 20.99  ? 235 TYR B CG  1 
ATOM   5539  C CD1 . TYR B 1 235 ? 145.524 142.690 100.260 1.00 20.99  ? 235 TYR B CD1 1 
ATOM   5540  C CD2 . TYR B 1 235 ? 144.824 141.097 101.886 1.00 20.99  ? 235 TYR B CD2 1 
ATOM   5541  C CE1 . TYR B 1 235 ? 144.241 142.745 99.756  1.00 20.99  ? 235 TYR B CE1 1 
ATOM   5542  C CE2 . TYR B 1 235 ? 143.542 141.145 101.390 1.00 20.99  ? 235 TYR B CE2 1 
ATOM   5543  C CZ  . TYR B 1 235 ? 143.254 141.970 100.326 1.00 20.99  ? 235 TYR B CZ  1 
ATOM   5544  O OH  . TYR B 1 235 ? 141.973 142.014 99.836  1.00 20.99  ? 235 TYR B OH  1 
ATOM   5545  N N   . TRP B 1 236 ? 149.145 141.638 104.317 1.00 22.77  ? 236 TRP B N   1 
ATOM   5546  C CA  . TRP B 1 236 ? 150.438 141.378 104.939 1.00 22.77  ? 236 TRP B CA  1 
ATOM   5547  C C   . TRP B 1 236 ? 150.734 139.882 104.957 1.00 22.77  ? 236 TRP B C   1 
ATOM   5548  O O   . TRP B 1 236 ? 149.830 139.046 104.932 1.00 22.77  ? 236 TRP B O   1 
ATOM   5549  C CB  . TRP B 1 236 ? 150.500 141.955 106.361 1.00 22.77  ? 236 TRP B CB  1 
ATOM   5550  C CG  . TRP B 1 236 ? 149.864 141.109 107.420 1.00 22.77  ? 236 TRP B CG  1 
ATOM   5551  C CD1 . TRP B 1 236 ? 150.435 140.072 108.098 1.00 22.77  ? 236 TRP B CD1 1 
ATOM   5552  C CD2 . TRP B 1 236 ? 148.538 141.244 107.941 1.00 22.77  ? 236 TRP B CD2 1 
ATOM   5553  N NE1 . TRP B 1 236 ? 149.545 139.547 108.998 1.00 22.77  ? 236 TRP B NE1 1 
ATOM   5554  C CE2 . TRP B 1 236 ? 148.372 140.250 108.922 1.00 22.77  ? 236 TRP B CE2 1 
ATOM   5555  C CE3 . TRP B 1 236 ? 147.475 142.106 107.668 1.00 22.77  ? 236 TRP B CE3 1 
ATOM   5556  C CZ2 . TRP B 1 236 ? 147.186 140.095 109.632 1.00 22.77  ? 236 TRP B CZ2 1 
ATOM   5557  C CZ3 . TRP B 1 236 ? 146.299 141.952 108.374 1.00 22.77  ? 236 TRP B CZ3 1 
ATOM   5558  C CH2 . TRP B 1 236 ? 146.163 140.954 109.344 1.00 22.77  ? 236 TRP B CH2 1 
ATOM   5559  N N   . THR B 1 237 ? 152.029 139.561 105.007 1.00 23.40  ? 237 THR B N   1 
ATOM   5560  C CA  . THR B 1 237 ? 152.515 138.184 105.016 1.00 23.40  ? 237 THR B CA  1 
ATOM   5561  C C   . THR B 1 237 ? 153.758 138.076 105.892 1.00 23.40  ? 237 THR B C   1 
ATOM   5562  O O   . THR B 1 237 ? 154.630 138.944 105.851 1.00 23.40  ? 237 THR B O   1 
ATOM   5563  C CB  . THR B 1 237 ? 152.845 137.696 103.595 1.00 23.40  ? 237 THR B CB  1 
ATOM   5564  O OG1 . THR B 1 237 ? 151.719 137.909 102.738 1.00 23.40  ? 237 THR B OG1 1 
ATOM   5565  C CG2 . THR B 1 237 ? 153.192 136.215 103.597 1.00 23.40  ? 237 THR B CG2 1 
ATOM   5566  N N   . ILE B 1 238 ? 153.849 137.001 106.671 1.00 25.04  ? 238 ILE B N   1 
ATOM   5567  C CA  . ILE B 1 238 ? 154.992 136.753 107.545 1.00 25.04  ? 238 ILE B CA  1 
ATOM   5568  C C   . ILE B 1 238 ? 155.785 135.574 106.997 1.00 25.04  ? 238 ILE B C   1 
ATOM   5569  O O   . ILE B 1 238 ? 155.214 134.521 106.693 1.00 25.04  ? 238 ILE B O   1 
ATOM   5570  C CB  . ILE B 1 238 ? 154.550 136.500 108.997 1.00 25.04  ? 238 ILE B CB  1 
ATOM   5571  C CG1 . ILE B 1 238 ? 154.097 137.810 109.638 1.00 25.04  ? 238 ILE B CG1 1 
ATOM   5572  C CG2 . ILE B 1 238 ? 155.684 135.894 109.806 1.00 25.04  ? 238 ILE B CG2 1 
ATOM   5573  C CD1 . ILE B 1 238 ? 153.366 137.637 110.926 1.00 25.04  ? 238 ILE B CD1 1 
ATOM   5574  N N   . VAL B 1 239 ? 157.098 135.755 106.868 1.00 27.36  ? 239 VAL B N   1 
ATOM   5575  C CA  . VAL B 1 239 ? 158.000 134.738 106.338 1.00 27.36  ? 239 VAL B CA  1 
ATOM   5576  C C   . VAL B 1 239 ? 158.958 134.320 107.447 1.00 27.36  ? 239 VAL B C   1 
ATOM   5577  O O   . VAL B 1 239 ? 159.715 135.150 107.969 1.00 27.36  ? 239 VAL B O   1 
ATOM   5578  C CB  . VAL B 1 239 ? 158.774 135.241 105.109 1.00 27.36  ? 239 VAL B CB  1 
ATOM   5579  C CG1 . VAL B 1 239 ? 159.650 134.137 104.545 1.00 27.36  ? 239 VAL B CG1 1 
ATOM   5580  C CG2 . VAL B 1 239 ? 157.816 135.760 104.050 1.00 27.36  ? 239 VAL B CG2 1 
ATOM   5581  N N   . LYS B 1 240 ? 158.930 133.035 107.795 1.00 31.73  ? 240 LYS B N   1 
ATOM   5582  C CA  . LYS B 1 240 ? 159.757 132.468 108.848 1.00 31.73  ? 240 LYS B CA  1 
ATOM   5583  C C   . LYS B 1 240 ? 161.158 132.143 108.333 1.00 31.73  ? 240 LYS B C   1 
ATOM   5584  O O   . LYS B 1 240 ? 161.366 131.996 107.127 1.00 31.73  ? 240 LYS B O   1 
ATOM   5585  C CB  . LYS B 1 240 ? 159.100 131.206 109.400 1.00 31.73  ? 240 LYS B CB  1 
ATOM   5586  C CG  . LYS B 1 240 ? 157.629 131.359 109.719 1.00 31.73  ? 240 LYS B CG  1 
ATOM   5587  C CD  . LYS B 1 240 ? 157.320 130.873 111.120 1.00 31.73  ? 240 LYS B CD  1 
ATOM   5588  C CE  . LYS B 1 240 ? 158.002 131.736 112.164 1.00 31.73  ? 240 LYS B CE  1 
ATOM   5589  N NZ  . LYS B 1 240 ? 157.250 131.753 113.446 1.00 31.73  ? 240 LYS B NZ  1 
ATOM   5590  N N   . PRO B 1 241 ? 162.139 132.033 109.229 1.00 32.52  ? 241 PRO B N   1 
ATOM   5591  C CA  . PRO B 1 241 ? 163.498 131.682 108.794 1.00 32.52  ? 241 PRO B CA  1 
ATOM   5592  C C   . PRO B 1 241 ? 163.524 130.346 108.065 1.00 32.52  ? 241 PRO B C   1 
ATOM   5593  O O   . PRO B 1 241 ? 162.922 129.364 108.504 1.00 32.52  ? 241 PRO B O   1 
ATOM   5594  C CB  . PRO B 1 241 ? 164.286 131.626 110.108 1.00 32.52  ? 241 PRO B CB  1 
ATOM   5595  C CG  . PRO B 1 241 ? 163.527 132.497 111.036 1.00 32.52  ? 241 PRO B CG  1 
ATOM   5596  C CD  . PRO B 1 241 ? 162.088 132.328 110.671 1.00 32.52  ? 241 PRO B CD  1 
ATOM   5597  N N   . GLY B 1 242 ? 164.237 130.317 106.943 1.00 33.51  ? 242 GLY B N   1 
ATOM   5598  C CA  . GLY B 1 242 ? 164.307 129.142 106.106 1.00 33.51  ? 242 GLY B CA  1 
ATOM   5599  C C   . GLY B 1 242 ? 163.206 129.013 105.077 1.00 33.51  ? 242 GLY B C   1 
ATOM   5600  O O   . GLY B 1 242 ? 163.234 128.065 104.284 1.00 33.51  ? 242 GLY B O   1 
ATOM   5601  N N   . ASP B 1 243 ? 162.242 129.928 105.059 1.00 33.49  ? 243 ASP B N   1 
ATOM   5602  C CA  . ASP B 1 243 ? 161.154 129.900 104.098 1.00 33.49  ? 243 ASP B CA  1 
ATOM   5603  C C   . ASP B 1 243 ? 161.460 130.841 102.935 1.00 33.49  ? 243 ASP B C   1 
ATOM   5604  O O   . ASP B 1 243 ? 162.523 131.460 102.861 1.00 33.49  ? 243 ASP B O   1 
ATOM   5605  C CB  . ASP B 1 243 ? 159.833 130.266 104.778 1.00 33.49  ? 243 ASP B CB  1 
ATOM   5606  C CG  . ASP B 1 243 ? 158.654 129.498 104.214 1.00 33.49  ? 243 ASP B CG  1 
ATOM   5607  O OD1 . ASP B 1 243 ? 158.636 129.242 102.994 1.00 33.49  ? 243 ASP B OD1 1 
ATOM   5608  O OD2 . ASP B 1 243 ? 157.739 129.159 104.991 1.00 33.49  ? 243 ASP B OD2 1 
ATOM   5609  N N   . VAL B 1 244 ? 160.507 130.948 102.012 1.00 31.62  ? 244 VAL B N   1 
ATOM   5610  C CA  . VAL B 1 244 ? 160.681 131.749 100.807 1.00 31.62  ? 244 VAL B CA  1 
ATOM   5611  C C   . VAL B 1 244 ? 159.341 132.369 100.435 1.00 31.62  ? 244 VAL B C   1 
ATOM   5612  O O   . VAL B 1 244 ? 158.283 131.771 100.639 1.00 31.62  ? 244 VAL B O   1 
ATOM   5613  C CB  . VAL B 1 244 ? 161.261 130.893 99.652  1.00 31.62  ? 244 VAL B CB  1 
ATOM   5614  C CG1 . VAL B 1 244 ? 160.322 129.755 99.305  1.00 31.62  ? 244 VAL B CG1 1 
ATOM   5615  C CG2 . VAL B 1 244 ? 161.545 131.747 98.433  1.00 31.62  ? 244 VAL B CG2 1 
ATOM   5616  N N   . LEU B 1 245 ? 159.392 133.587 99.903  1.00 27.82  ? 245 LEU B N   1 
ATOM   5617  C CA  . LEU B 1 245 ? 158.215 134.301 99.433  1.00 27.82  ? 245 LEU B CA  1 
ATOM   5618  C C   . LEU B 1 245 ? 158.207 134.330 97.912  1.00 27.82  ? 245 LEU B C   1 
ATOM   5619  O O   . LEU B 1 245 ? 159.238 134.587 97.284  1.00 27.82  ? 245 LEU B O   1 
ATOM   5620  C CB  . LEU B 1 245 ? 158.193 135.731 99.981  1.00 27.82  ? 245 LEU B CB  1 
ATOM   5621  C CG  . LEU B 1 245 ? 157.022 136.627 99.577  1.00 27.82  ? 245 LEU B CG  1 
ATOM   5622  C CD1 . LEU B 1 245 ? 155.843 136.384 100.497 1.00 27.82  ? 245 LEU B CD1 1 
ATOM   5623  C CD2 . LEU B 1 245 ? 157.430 138.087 99.598  1.00 27.82  ? 245 LEU B CD2 1 
ATOM   5624  N N   . VAL B 1 246 ? 157.046 134.058 97.320  1.00 27.42  ? 246 VAL B N   1 
ATOM   5625  C CA  . VAL B 1 246 ? 156.859 134.131 95.876  1.00 27.42  ? 246 VAL B CA  1 
ATOM   5626  C C   . VAL B 1 246 ? 155.689 135.062 95.588  1.00 27.42  ? 246 VAL B C   1 
ATOM   5627  O O   . VAL B 1 246 ? 154.618 134.932 96.196  1.00 27.42  ? 246 VAL B O   1 
ATOM   5628  C CB  . VAL B 1 246 ? 156.621 132.742 95.248  1.00 27.42  ? 246 VAL B CB  1 
ATOM   5629  C CG1 . VAL B 1 246 ? 156.316 132.874 93.769  1.00 27.42  ? 246 VAL B CG1 1 
ATOM   5630  C CG2 . VAL B 1 246 ? 157.835 131.853 95.448  1.00 27.42  ? 246 VAL B CG2 1 
ATOM   5631  N N   . ILE B 1 247 ? 155.903 136.004 94.673  1.00 26.77  ? 247 ILE B N   1 
ATOM   5632  C CA  . ILE B 1 247 ? 154.883 136.947 94.230  1.00 26.77  ? 247 ILE B CA  1 
ATOM   5633  C C   . ILE B 1 247 ? 154.655 136.718 92.743  1.00 26.77  ? 247 ILE B C   1 
ATOM   5634  O O   . ILE B 1 247 ? 155.593 136.823 91.941  1.00 26.77  ? 247 ILE B O   1 
ATOM   5635  C CB  . ILE B 1 247 ? 155.288 138.404 94.504  1.00 26.77  ? 247 ILE B CB  1 
ATOM   5636  C CG1 . ILE B 1 247 ? 155.549 138.620 95.996  1.00 26.77  ? 247 ILE B CG1 1 
ATOM   5637  C CG2 . ILE B 1 247 ? 154.218 139.362 94.003  1.00 26.77  ? 247 ILE B CG2 1 
ATOM   5638  C CD1 . ILE B 1 247 ? 156.314 139.881 96.304  1.00 26.77  ? 247 ILE B CD1 1 
ATOM   5639  N N   . ASN B 1 248 ? 153.410 136.414 92.378  1.00 28.28  ? 248 ASN B N   1 
ATOM   5640  C CA  . ASN B 1 248 ? 153.028 136.098 91.007  1.00 28.28  ? 248 ASN B CA  1 
ATOM   5641  C C   . ASN B 1 248 ? 151.829 136.958 90.642  1.00 28.28  ? 248 ASN B C   1 
ATOM   5642  O O   . ASN B 1 248 ? 150.772 136.850 91.267  1.00 28.28  ? 248 ASN B O   1 
ATOM   5643  C CB  . ASN B 1 248 ? 152.698 134.608 90.865  1.00 28.28  ? 248 ASN B CB  1 
ATOM   5644  C CG  . ASN B 1 248 ? 152.168 134.251 89.491  1.00 28.28  ? 248 ASN B CG  1 
ATOM   5645  O OD1 . ASN B 1 248 ? 150.970 134.330 89.237  1.00 28.28  ? 248 ASN B OD1 1 
ATOM   5646  N ND2 . ASN B 1 248 ? 153.059 133.839 88.601  1.00 28.28  ? 248 ASN B ND2 1 
ATOM   5647  N N   . SER B 1 249 ? 151.983 137.806 89.632  1.00 29.11  ? 249 SER B N   1 
ATOM   5648  C CA  . SER B 1 249 ? 150.912 138.753 89.349  1.00 29.11  ? 249 SER B CA  1 
ATOM   5649  C C   . SER B 1 249 ? 150.840 139.068 87.867  1.00 29.11  ? 249 SER B C   1 
ATOM   5650  O O   . SER B 1 249 ? 151.855 139.075 87.165  1.00 29.11  ? 249 SER B O   1 
ATOM   5651  C CB  . SER B 1 249 ? 151.089 140.056 90.136  1.00 29.11  ? 249 SER B CB  1 
ATOM   5652  O OG  . SER B 1 249 ? 150.160 141.034 89.708  1.00 29.11  ? 249 SER B OG  1 
ATOM   5653  N N   . ASN B 1 250 ? 149.622 139.355 87.401  1.00 30.63  ? 250 ASN B N   1 
ATOM   5654  C CA  . ASN B 1 250 ? 149.456 139.790 86.018  1.00 30.63  ? 250 ASN B CA  1 
ATOM   5655  C C   . ASN B 1 250 ? 148.651 141.084 85.924  1.00 30.63  ? 250 ASN B C   1 
ATOM   5656  O O   . ASN B 1 250 ? 148.045 141.373 84.890  1.00 30.63  ? 250 ASN B O   1 
ATOM   5657  C CB  . ASN B 1 250 ? 148.841 138.680 85.159  1.00 30.63  ? 250 ASN B CB  1 
ATOM   5658  C CG  . ASN B 1 250 ? 147.343 138.550 85.332  1.00 30.63  ? 250 ASN B CG  1 
ATOM   5659  O OD1 . ASN B 1 250 ? 146.824 138.611 86.443  1.00 30.63  ? 250 ASN B OD1 1 
ATOM   5660  N ND2 . ASN B 1 250 ? 146.640 138.355 84.227  1.00 30.63  ? 250 ASN B ND2 1 
ATOM   5661  N N   . GLY B 1 251 ? 148.666 141.883 86.974  1.00 28.03  ? 251 GLY B N   1 
ATOM   5662  C CA  . GLY B 1 251 ? 148.029 143.187 86.975  1.00 28.03  ? 251 GLY B CA  1 
ATOM   5663  C C   . GLY B 1 251 ? 147.592 143.599 88.368  1.00 28.03  ? 251 GLY B C   1 
ATOM   5664  O O   . GLY B 1 251 ? 147.303 142.778 89.231  1.00 28.03  ? 251 GLY B O   1 
ATOM   5665  N N   . ASN B 1 252 ? 147.561 144.916 88.589  1.00 26.61  ? 252 ASN B N   1 
ATOM   5666  C CA  . ASN B 1 252 ? 146.978 145.557 89.768  1.00 26.61  ? 252 ASN B CA  1 
ATOM   5667  C C   . ASN B 1 252 ? 147.792 145.350 91.043  1.00 26.61  ? 252 ASN B C   1 
ATOM   5668  O O   . ASN B 1 252 ? 147.248 145.471 92.143  1.00 26.61  ? 252 ASN B O   1 
ATOM   5669  C CB  . ASN B 1 252 ? 145.533 145.092 90.009  1.00 26.61  ? 252 ASN B CB  1 
ATOM   5670  C CG  . ASN B 1 252 ? 144.630 145.322 88.810  1.00 26.61  ? 252 ASN B CG  1 
ATOM   5671  O OD1 . ASN B 1 252 ? 144.804 144.708 87.761  1.00 26.61  ? 252 ASN B OD1 1 
ATOM   5672  N ND2 . ASN B 1 252 ? 143.650 146.200 88.969  1.00 26.61  ? 252 ASN B ND2 1 
ATOM   5673  N N   . LEU B 1 253 ? 149.084 145.050 90.941  1.00 23.67  ? 253 LEU B N   1 
ATOM   5674  C CA  . LEU B 1 253 ? 149.905 144.787 92.117  1.00 23.67  ? 253 LEU B CA  1 
ATOM   5675  C C   . LEU B 1 253 ? 150.529 146.074 92.646  1.00 23.67  ? 253 LEU B C   1 
ATOM   5676  O O   . LEU B 1 253 ? 151.074 146.872 91.878  1.00 23.67  ? 253 LEU B O   1 
ATOM   5677  C CB  . LEU B 1 253 ? 151.002 143.769 91.795  1.00 23.67  ? 253 LEU B CB  1 
ATOM   5678  C CG  . LEU B 1 253 ? 152.159 143.650 92.795  1.00 23.67  ? 253 LEU B CG  1 
ATOM   5679  C CD1 . LEU B 1 253 ? 151.729 142.943 94.072  1.00 23.67  ? 253 LEU B CD1 1 
ATOM   5680  C CD2 . LEU B 1 253 ? 153.351 142.947 92.165  1.00 23.67  ? 253 LEU B CD2 1 
ATOM   5681  N N   . ILE B 1 254 ? 150.444 146.267 93.959  1.00 22.34  ? 254 ILE B N   1 
ATOM   5682  C CA  . ILE B 1 254 ? 151.177 147.308 94.671  1.00 22.34  ? 254 ILE B CA  1 
ATOM   5683  C C   . ILE B 1 254 ? 152.301 146.600 95.418  1.00 22.34  ? 254 ILE B C   1 
ATOM   5684  O O   . ILE B 1 254 ? 152.080 146.013 96.482  1.00 22.34  ? 254 ILE B O   1 
ATOM   5685  C CB  . ILE B 1 254 ? 150.276 148.103 95.625  1.00 22.34  ? 254 ILE B CB  1 
ATOM   5686  C CG1 . ILE B 1 254 ? 148.997 148.560 94.915  1.00 22.34  ? 254 ILE B CG1 1 
ATOM   5687  C CG2 . ILE B 1 254 ? 151.027 149.293 96.206  1.00 22.34  ? 254 ILE B CG2 1 
ATOM   5688  C CD1 . ILE B 1 254 ? 149.215 149.640 93.881  1.00 22.34  ? 254 ILE B CD1 1 
ATOM   5689  N N   . ALA B 1 255 ? 153.508 146.649 94.869  1.00 22.79  ? 255 ALA B N   1 
ATOM   5690  C CA  . ALA B 1 255 ? 154.594 145.802 95.333  1.00 22.79  ? 255 ALA B CA  1 
ATOM   5691  C C   . ALA B 1 255 ? 155.227 146.334 96.619  1.00 22.79  ? 255 ALA B C   1 
ATOM   5692  O O   . ALA B 1 255 ? 155.248 147.543 96.861  1.00 22.79  ? 255 ALA B O   1 
ATOM   5693  C CB  . ALA B 1 255 ? 155.660 145.682 94.254  1.00 22.79  ? 255 ALA B CB  1 
ATOM   5694  N N   . PRO B 1 256 ? 155.745 145.445 97.462  1.00 23.02  ? 256 PRO B N   1 
ATOM   5695  C CA  . PRO B 1 256 ? 156.565 145.889 98.591  1.00 23.02  ? 256 PRO B CA  1 
ATOM   5696  C C   . PRO B 1 256 ? 157.953 146.310 98.133  1.00 23.02  ? 256 PRO B C   1 
ATOM   5697  O O   . PRO B 1 256 ? 158.441 145.912 97.074  1.00 23.02  ? 256 PRO B O   1 
ATOM   5698  C CB  . PRO B 1 256 ? 156.629 144.651 99.489  1.00 23.02  ? 256 PRO B CB  1 
ATOM   5699  C CG  . PRO B 1 256 ? 156.483 143.514 98.551  1.00 23.02  ? 256 PRO B CG  1 
ATOM   5700  C CD  . PRO B 1 256 ? 155.595 143.980 97.429  1.00 23.02  ? 256 PRO B CD  1 
ATOM   5701  N N   . ARG B 1 257 ? 158.590 147.139 98.956  1.00 23.42  ? 257 ARG B N   1 
ATOM   5702  C CA  . ARG B 1 257 ? 159.957 147.579 98.716  1.00 23.42  ? 257 ARG B CA  1 
ATOM   5703  C C   . ARG B 1 257 ? 160.959 146.912 99.645  1.00 23.42  ? 257 ARG B C   1 
ATOM   5704  O O   . ARG B 1 257 ? 162.166 147.113 99.481  1.00 23.42  ? 257 ARG B O   1 
ATOM   5705  C CB  . ARG B 1 257 ? 160.056 149.102 98.862  1.00 23.42  ? 257 ARG B CB  1 
ATOM   5706  C CG  . ARG B 1 257 ? 159.389 149.880 97.750  1.00 23.42  ? 257 ARG B CG  1 
ATOM   5707  C CD  . ARG B 1 257 ? 159.681 151.360 97.876  1.00 23.42  ? 257 ARG B CD  1 
ATOM   5708  N NE  . ARG B 1 257 ? 158.855 152.165 96.987  1.00 23.42  ? 257 ARG B NE  1 
ATOM   5709  C CZ  . ARG B 1 257 ? 159.202 152.525 95.759  1.00 23.42  ? 257 ARG B CZ  1 
ATOM   5710  N NH1 . ARG B 1 257 ? 160.353 152.150 95.227  1.00 23.42  ? 257 ARG B NH1 1 
ATOM   5711  N NH2 . ARG B 1 257 ? 158.373 153.282 95.048  1.00 23.42  ? 257 ARG B NH2 1 
ATOM   5712  N N   . GLY B 1 258 ? 160.491 146.117 100.601 1.00 23.72  ? 258 GLY B N   1 
ATOM   5713  C CA  . GLY B 1 258 ? 161.363 145.516 101.592 1.00 23.72  ? 258 GLY B CA  1 
ATOM   5714  C C   . GLY B 1 258 ? 160.527 144.847 102.664 1.00 23.72  ? 258 GLY B C   1 
ATOM   5715  O O   . GLY B 1 258 ? 159.370 144.500 102.431 1.00 23.72  ? 258 GLY B O   1 
ATOM   5716  N N   . PHE B 1 259 ? 161.121 144.679 103.843 1.00 23.28  ? 259 PHE B N   1 
ATOM   5717  C CA  . PHE B 1 259 ? 160.417 144.008 104.929 1.00 23.28  ? 259 PHE B CA  1 
ATOM   5718  C C   . PHE B 1 259 ? 160.600 144.758 106.242 1.00 23.28  ? 259 PHE B C   1 
ATOM   5719  O O   . PHE B 1 259 ? 161.557 145.511 106.433 1.00 23.28  ? 259 PHE B O   1 
ATOM   5720  C CB  . PHE B 1 259 ? 160.862 142.540 105.083 1.00 23.28  ? 259 PHE B CB  1 
ATOM   5721  C CG  . PHE B 1 259 ? 162.281 142.368 105.551 1.00 23.28  ? 259 PHE B CG  1 
ATOM   5722  C CD1 . PHE B 1 259 ? 162.578 142.292 106.902 1.00 23.28  ? 259 PHE B CD1 1 
ATOM   5723  C CD2 . PHE B 1 259 ? 163.317 142.266 104.639 1.00 23.28  ? 259 PHE B CD2 1 
ATOM   5724  C CE1 . PHE B 1 259 ? 163.878 142.132 107.331 1.00 23.28  ? 259 PHE B CE1 1 
ATOM   5725  C CE2 . PHE B 1 259 ? 164.619 142.104 105.064 1.00 23.28  ? 259 PHE B CE2 1 
ATOM   5726  C CZ  . PHE B 1 259 ? 164.900 142.037 106.410 1.00 23.28  ? 259 PHE B CZ  1 
ATOM   5727  N N   . PHE B 1 260 ? 159.654 144.532 107.149 1.00 24.78  ? 260 PHE B N   1 
ATOM   5728  C CA  . PHE B 1 260 ? 159.692 145.059 108.505 1.00 24.78  ? 260 PHE B CA  1 
ATOM   5729  C C   . PHE B 1 260 ? 160.180 143.979 109.462 1.00 24.78  ? 260 PHE B C   1 
ATOM   5730  O O   . PHE B 1 260 ? 159.800 142.812 109.342 1.00 24.78  ? 260 PHE B O   1 
ATOM   5731  C CB  . PHE B 1 260 ? 158.308 145.533 108.960 1.00 24.78  ? 260 PHE B CB  1 
ATOM   5732  C CG  . PHE B 1 260 ? 157.831 146.791 108.291 1.00 24.78  ? 260 PHE B CG  1 
ATOM   5733  C CD1 . PHE B 1 260 ? 158.168 148.033 108.800 1.00 24.78  ? 260 PHE B CD1 1 
ATOM   5734  C CD2 . PHE B 1 260 ? 157.020 146.731 107.171 1.00 24.78  ? 260 PHE B CD2 1 
ATOM   5735  C CE1 . PHE B 1 260 ? 157.722 149.190 108.194 1.00 24.78  ? 260 PHE B CE1 1 
ATOM   5736  C CE2 . PHE B 1 260 ? 156.569 147.884 106.561 1.00 24.78  ? 260 PHE B CE2 1 
ATOM   5737  C CZ  . PHE B 1 260 ? 156.921 149.115 107.074 1.00 24.78  ? 260 PHE B CZ  1 
ATOM   5738  N N   . LYS B 1 261 ? 161.025 144.370 110.410 1.00 30.54  ? 261 LYS B N   1 
ATOM   5739  C CA  . LYS B 1 261 ? 161.356 143.476 111.508 1.00 30.54  ? 261 LYS B CA  1 
ATOM   5740  C C   . LYS B 1 261 ? 160.180 143.389 112.472 1.00 30.54  ? 261 LYS B C   1 
ATOM   5741  O O   . LYS B 1 261 ? 159.522 144.390 112.764 1.00 30.54  ? 261 LYS B O   1 
ATOM   5742  C CB  . LYS B 1 261 ? 162.603 143.961 112.241 1.00 30.54  ? 261 LYS B CB  1 
ATOM   5743  C CG  . LYS B 1 261 ? 163.884 143.820 111.448 1.00 30.54  ? 261 LYS B CG  1 
ATOM   5744  C CD  . LYS B 1 261 ? 164.895 142.974 112.196 1.00 30.54  ? 261 LYS B CD  1 
ATOM   5745  C CE  . LYS B 1 261 ? 166.291 143.553 112.073 1.00 30.54  ? 261 LYS B CE  1 
ATOM   5746  N NZ  . LYS B 1 261 ? 166.683 143.727 110.651 1.00 30.54  ? 261 LYS B NZ  1 
ATOM   5747  N N   . ILE B 1 262 ? 159.907 142.186 112.961 1.00 31.99  ? 262 ILE B N   1 
ATOM   5748  C CA  . ILE B 1 262 ? 158.819 141.951 113.900 1.00 31.99  ? 262 ILE B CA  1 
ATOM   5749  C C   . ILE B 1 262 ? 159.401 141.303 115.148 1.00 31.99  ? 262 ILE B C   1 
ATOM   5750  O O   . ILE B 1 262 ? 160.149 140.323 115.058 1.00 31.99  ? 262 ILE B O   1 
ATOM   5751  C CB  . ILE B 1 262 ? 157.699 141.094 113.277 1.00 31.99  ? 262 ILE B CB  1 
ATOM   5752  C CG1 . ILE B 1 262 ? 156.609 140.796 114.309 1.00 31.99  ? 262 ILE B CG1 1 
ATOM   5753  C CG2 . ILE B 1 262 ? 158.251 139.824 112.657 1.00 31.99  ? 262 ILE B CG2 1 
ATOM   5754  C CD1 . ILE B 1 262 ? 155.328 140.272 113.705 1.00 31.99  ? 262 ILE B CD1 1 
ATOM   5755  N N   . ARG B 1 263 ? 159.074 141.865 116.308 1.00 34.57  ? 263 ARG B N   1 
ATOM   5756  C CA  . ARG B 1 263 ? 159.682 141.468 117.566 1.00 34.57  ? 263 ARG B CA  1 
ATOM   5757  C C   . ARG B 1 263 ? 158.600 141.082 118.561 1.00 34.57  ? 263 ARG B C   1 
ATOM   5758  O O   . ARG B 1 263 ? 157.420 141.392 118.384 1.00 34.57  ? 263 ARG B O   1 
ATOM   5759  C CB  . ARG B 1 263 ? 160.551 142.594 118.144 1.00 34.57  ? 263 ARG B CB  1 
ATOM   5760  C CG  . ARG B 1 263 ? 161.775 142.911 117.307 1.00 34.57  ? 263 ARG B CG  1 
ATOM   5761  C CD  . ARG B 1 263 ? 162.695 143.896 118.006 1.00 34.57  ? 263 ARG B CD  1 
ATOM   5762  N NE  . ARG B 1 263 ? 163.130 144.956 117.104 1.00 34.57  ? 263 ARG B NE  1 
ATOM   5763  C CZ  . ARG B 1 263 ? 164.128 144.845 116.238 1.00 34.57  ? 263 ARG B CZ  1 
ATOM   5764  N NH1 . ARG B 1 263 ? 164.844 143.737 116.147 1.00 34.57  ? 263 ARG B NH1 1 
ATOM   5765  N NH2 . ARG B 1 263 ? 164.415 145.873 115.444 1.00 34.57  ? 263 ARG B NH2 1 
ATOM   5766  N N   . THR B 1 264 ? 159.021 140.381 119.606 1.00 36.74  ? 264 THR B N   1 
ATOM   5767  C CA  . THR B 1 264 ? 158.167 140.060 120.740 1.00 36.74  ? 264 THR B CA  1 
ATOM   5768  C C   . THR B 1 264 ? 158.563 140.949 121.911 1.00 36.74  ? 264 THR B C   1 
ATOM   5769  O O   . THR B 1 264 ? 159.751 141.079 122.221 1.00 36.74  ? 264 THR B O   1 
ATOM   5770  C CB  . THR B 1 264 ? 158.295 138.586 121.129 1.00 36.74  ? 264 THR B CB  1 
ATOM   5771  O OG1 . THR B 1 264 ? 157.991 137.760 119.997 1.00 36.74  ? 264 THR B OG1 1 
ATOM   5772  C CG2 . THR B 1 264 ? 157.343 138.250 122.263 1.00 36.74  ? 264 THR B CG2 1 
ATOM   5773  N N   . GLY B 1 265 ? 157.578 141.560 122.548 1.00 34.83  ? 265 GLY B N   1 
ATOM   5774  C CA  . GLY B 1 265 ? 157.869 142.444 123.651 1.00 34.83  ? 265 GLY B CA  1 
ATOM   5775  C C   . GLY B 1 265 ? 156.618 142.859 124.384 1.00 34.83  ? 265 GLY B C   1 
ATOM   5776  O O   . GLY B 1 265 ? 155.578 142.206 124.293 1.00 34.83  ? 265 GLY B O   1 
ATOM   5777  N N   . ARG B 1 266 ? 156.734 143.969 125.110 1.00 33.50  ? 266 ARG B N   1 
ATOM   5778  C CA  . ARG B 1 266 ? 155.664 144.468 125.963 1.00 33.50  ? 266 ARG B CA  1 
ATOM   5779  C C   . ARG B 1 266 ? 155.158 145.838 125.513 1.00 33.50  ? 266 ARG B C   1 
ATOM   5780  O O   . ARG B 1 266 ? 154.687 146.628 126.331 1.00 33.50  ? 266 ARG B O   1 
ATOM   5781  C CB  . ARG B 1 266 ? 156.129 144.510 127.419 1.00 33.50  ? 266 ARG B CB  1 
ATOM   5782  C CG  . ARG B 1 266 ? 157.402 145.311 127.647 1.00 33.50  ? 266 ARG B CG  1 
ATOM   5783  C CD  . ARG B 1 266 ? 157.108 146.632 128.332 1.00 33.50  ? 266 ARG B CD  1 
ATOM   5784  N NE  . ARG B 1 266 ? 158.309 147.283 128.838 1.00 33.50  ? 266 ARG B NE  1 
ATOM   5785  C CZ  . ARG B 1 266 ? 158.340 148.521 129.312 1.00 33.50  ? 266 ARG B CZ  1 
ATOM   5786  N NH1 . ARG B 1 266 ? 157.250 149.268 129.361 1.00 33.50  ? 266 ARG B NH1 1 
ATOM   5787  N NH2 . ARG B 1 266 ? 159.493 149.021 129.748 1.00 33.50  ? 266 ARG B NH2 1 
ATOM   5788  N N   . SER B 1 267 ? 155.237 146.128 124.216 1.00 28.80  ? 267 SER B N   1 
ATOM   5789  C CA  . SER B 1 267 ? 154.768 147.402 123.688 1.00 28.80  ? 267 SER B CA  1 
ATOM   5790  C C   . SER B 1 267 ? 153.265 147.358 123.416 1.00 28.80  ? 267 SER B C   1 
ATOM   5791  O O   . SER B 1 267 ? 152.669 146.292 123.250 1.00 28.80  ? 267 SER B O   1 
ATOM   5792  C CB  . SER B 1 267 ? 155.520 147.763 122.408 1.00 28.80  ? 267 SER B CB  1 
ATOM   5793  O OG  . SER B 1 267 ? 156.878 148.053 122.674 1.00 28.80  ? 267 SER B OG  1 
ATOM   5794  N N   . SER B 1 268 ? 152.653 148.540 123.365 1.00 26.99  ? 268 SER B N   1 
ATOM   5795  C CA  . SER B 1 268 ? 151.213 148.652 123.160 1.00 26.99  ? 268 SER B CA  1 
ATOM   5796  C C   . SER B 1 268 ? 150.893 150.030 122.588 1.00 26.99  ? 268 SER B C   1 
ATOM   5797  O O   . SER B 1 268 ? 151.785 150.842 122.332 1.00 26.99  ? 268 SER B O   1 
ATOM   5798  C CB  . SER B 1 268 ? 150.451 148.396 124.463 1.00 26.99  ? 268 SER B CB  1 
ATOM   5799  O OG  . SER B 1 268 ? 149.076 148.175 124.214 1.00 26.99  ? 268 SER B OG  1 
ATOM   5800  N N   . ILE B 1 269 ? 149.597 150.288 122.400 1.00 25.26  ? 269 ILE B N   1 
ATOM   5801  C CA  . ILE B 1 269 ? 149.096 151.533 121.831 1.00 25.26  ? 269 ILE B CA  1 
ATOM   5802  C C   . ILE B 1 269 ? 147.900 152.001 122.654 1.00 25.26  ? 269 ILE B C   1 
ATOM   5803  O O   . ILE B 1 269 ? 147.181 151.195 123.250 1.00 25.26  ? 269 ILE B O   1 
ATOM   5804  C CB  . ILE B 1 269 ? 148.719 151.358 120.337 1.00 25.26  ? 269 ILE B CB  1 
ATOM   5805  C CG1 . ILE B 1 269 ? 148.355 152.696 119.692 1.00 25.26  ? 269 ILE B CG1 1 
ATOM   5806  C CG2 . ILE B 1 269 ? 147.583 150.358 120.173 1.00 25.26  ? 269 ILE B CG2 1 
ATOM   5807  C CD1 . ILE B 1 269 ? 148.353 152.659 118.182 1.00 25.26  ? 269 ILE B CD1 1 
ATOM   5808  N N   . MET B 1 270 ? 147.691 153.317 122.693 1.00 27.35  ? 270 MET B N   1 
ATOM   5809  C CA  . MET B 1 270 ? 146.616 153.901 123.487 1.00 27.35  ? 270 MET B CA  1 
ATOM   5810  C C   . MET B 1 270 ? 146.081 155.151 122.801 1.00 27.35  ? 270 MET B C   1 
ATOM   5811  O O   . MET B 1 270 ? 146.839 155.895 122.176 1.00 27.35  ? 270 MET B O   1 
ATOM   5812  C CB  . MET B 1 270 ? 147.102 154.240 124.904 1.00 27.35  ? 270 MET B CB  1 
ATOM   5813  C CG  . MET B 1 270 ? 146.014 154.700 125.860 1.00 27.35  ? 270 MET B CG  1 
ATOM   5814  S SD  . MET B 1 270 ? 146.659 155.364 127.411 1.00 27.35  ? 270 MET B SD  1 
ATOM   5815  C CE  . MET B 1 270 ? 146.938 153.859 128.338 1.00 27.35  ? 270 MET B CE  1 
ATOM   5816  N N   . ARG B 1 271 ? 144.774 155.378 122.930 1.00 26.90  ? 271 ARG B N   1 
ATOM   5817  C CA  . ARG B 1 271 ? 144.119 156.578 122.418 1.00 26.90  ? 271 ARG B CA  1 
ATOM   5818  C C   . ARG B 1 271 ? 143.941 157.568 123.564 1.00 26.90  ? 271 ARG B C   1 
ATOM   5819  O O   . ARG B 1 271 ? 143.302 157.245 124.570 1.00 26.90  ? 271 ARG B O   1 
ATOM   5820  C CB  . ARG B 1 271 ? 142.760 156.245 121.800 1.00 26.90  ? 271 ARG B CB  1 
ATOM   5821  C CG  . ARG B 1 271 ? 142.791 155.314 120.601 1.00 26.90  ? 271 ARG B CG  1 
ATOM   5822  C CD  . ARG B 1 271 ? 141.385 155.112 120.048 1.00 26.90  ? 271 ARG B CD  1 
ATOM   5823  N NE  . ARG B 1 271 ? 141.346 154.192 118.917 1.00 26.90  ? 271 ARG B NE  1 
ATOM   5824  C CZ  . ARG B 1 271 ? 141.102 152.892 119.012 1.00 26.90  ? 271 ARG B CZ  1 
ATOM   5825  N NH1 . ARG B 1 271 ? 140.860 152.317 120.178 1.00 26.90  ? 271 ARG B NH1 1 
ATOM   5826  N NH2 . ARG B 1 271 ? 141.100 152.150 117.909 1.00 26.90  ? 271 ARG B NH2 1 
ATOM   5827  N N   . SER B 1 272 ? 144.492 158.771 123.410 1.00 29.70  ? 272 SER B N   1 
ATOM   5828  C CA  . SER B 1 272 ? 144.391 159.776 124.460 1.00 29.70  ? 272 SER B CA  1 
ATOM   5829  C C   . SER B 1 272 ? 144.678 161.153 123.883 1.00 29.70  ? 272 SER B C   1 
ATOM   5830  O O   . SER B 1 272 ? 145.375 161.285 122.875 1.00 29.70  ? 272 SER B O   1 
ATOM   5831  C CB  . SER B 1 272 ? 145.356 159.476 125.614 1.00 29.70  ? 272 SER B CB  1 
ATOM   5832  O OG  . SER B 1 272 ? 145.350 160.517 126.573 1.00 29.70  ? 272 SER B OG  1 
ATOM   5833  N N   . ASP B 1 273 ? 144.137 162.178 124.542 1.00 33.28  ? 273 ASP B N   1 
ATOM   5834  C CA  . ASP B 1 273 ? 144.422 163.568 124.209 1.00 33.28  ? 273 ASP B CA  1 
ATOM   5835  C C   . ASP B 1 273 ? 145.182 164.291 125.314 1.00 33.28  ? 273 ASP B C   1 
ATOM   5836  O O   . ASP B 1 273 ? 145.382 165.506 125.221 1.00 33.28  ? 273 ASP B O   1 
ATOM   5837  C CB  . ASP B 1 273 ? 143.124 164.316 123.894 1.00 33.28  ? 273 ASP B CB  1 
ATOM   5838  C CG  . ASP B 1 273 ? 142.610 164.034 122.496 1.00 33.28  ? 273 ASP B CG  1 
ATOM   5839  O OD1 . ASP B 1 273 ? 143.427 163.960 121.556 1.00 33.28  ? 273 ASP B OD1 1 
ATOM   5840  O OD2 . ASP B 1 273 ? 141.383 163.887 122.336 1.00 33.28  ? 273 ASP B OD2 1 
ATOM   5841  N N   . ALA B 1 274 ? 145.606 163.581 126.354 1.00 32.73  ? 274 ALA B N   1 
ATOM   5842  C CA  . ALA B 1 274 ? 146.322 164.215 127.452 1.00 32.73  ? 274 ALA B CA  1 
ATOM   5843  C C   . ALA B 1 274 ? 147.721 164.639 127.007 1.00 32.73  ? 274 ALA B C   1 
ATOM   5844  O O   . ALA B 1 274 ? 148.385 163.911 126.264 1.00 32.73  ? 274 ALA B O   1 
ATOM   5845  C CB  . ALA B 1 274 ? 146.420 163.266 128.644 1.00 32.73  ? 274 ALA B CB  1 
ATOM   5846  N N   . PRO B 1 275 ? 148.196 165.802 127.442 1.00 34.14  ? 275 PRO B N   1 
ATOM   5847  C CA  . PRO B 1 275 ? 149.552 166.230 127.082 1.00 34.14  ? 275 PRO B CA  1 
ATOM   5848  C C   . PRO B 1 275 ? 150.615 165.426 127.817 1.00 34.14  ? 275 PRO B C   1 
ATOM   5849  O O   . PRO B 1 275 ? 150.373 164.817 128.859 1.00 34.14  ? 275 PRO B O   1 
ATOM   5850  C CB  . PRO B 1 275 ? 149.584 167.703 127.500 1.00 34.14  ? 275 PRO B CB  1 
ATOM   5851  C CG  . PRO B 1 275 ? 148.552 167.811 128.557 1.00 34.14  ? 275 PRO B CG  1 
ATOM   5852  C CD  . PRO B 1 275 ? 147.473 166.836 128.201 1.00 34.14  ? 275 PRO B CD  1 
ATOM   5853  N N   . ILE B 1 276 ? 151.819 165.444 127.254 1.00 35.59  ? 276 ILE B N   1 
ATOM   5854  C CA  . ILE B 1 276 ? 152.958 164.690 127.765 1.00 35.59  ? 276 ILE B CA  1 
ATOM   5855  C C   . ILE B 1 276 ? 153.922 165.661 128.432 1.00 35.59  ? 276 ILE B C   1 
ATOM   5856  O O   . ILE B 1 276 ? 154.283 166.687 127.843 1.00 35.59  ? 276 ILE B O   1 
ATOM   5857  C CB  . ILE B 1 276 ? 153.651 163.899 126.642 1.00 35.59  ? 276 ILE B CB  1 
ATOM   5858  C CG1 . ILE B 1 276 ? 152.651 162.961 125.965 1.00 35.59  ? 276 ILE B CG1 1 
ATOM   5859  C CG2 . ILE B 1 276 ? 154.844 163.127 127.182 1.00 35.59  ? 276 ILE B CG2 1 
ATOM   5860  C CD1 . ILE B 1 276 ? 153.230 162.161 124.830 1.00 35.59  ? 276 ILE B CD1 1 
ATOM   5861  N N   . GLU B 1 277 ? 154.338 165.339 129.656 1.00 40.53  ? 277 GLU B N   1 
ATOM   5862  C CA  . GLU B 1 277 ? 155.199 166.200 130.455 1.00 40.53  ? 277 GLU B CA  1 
ATOM   5863  C C   . GLU B 1 277 ? 156.371 165.397 131.003 1.00 40.53  ? 277 GLU B C   1 
ATOM   5864  O O   . GLU B 1 277 ? 156.382 164.165 130.972 1.00 40.53  ? 277 GLU B O   1 
ATOM   5865  C CB  . GLU B 1 277 ? 154.425 166.849 131.610 1.00 40.53  ? 277 GLU B CB  1 
ATOM   5866  C CG  . GLU B 1 277 ? 153.182 167.609 131.182 1.00 40.53  ? 277 GLU B CG  1 
ATOM   5867  C CD  . GLU B 1 277 ? 153.489 169.013 130.705 1.00 40.53  ? 277 GLU B CD  1 
ATOM   5868  O OE1 . GLU B 1 277 ? 153.519 169.934 131.549 1.00 40.53  ? 277 GLU B OE1 1 
ATOM   5869  O OE2 . GLU B 1 277 ? 153.697 169.198 129.487 1.00 40.53  ? 277 GLU B OE2 1 
ATOM   5870  N N   . THR B 1 278 ? 157.365 166.119 131.518 1.00 41.24  ? 278 THR B N   1 
ATOM   5871  C CA  . THR B 1 278 ? 158.572 165.517 132.084 1.00 41.24  ? 278 THR B CA  1 
ATOM   5872  C C   . THR B 1 278 ? 158.325 165.210 133.557 1.00 41.24  ? 278 THR B C   1 
ATOM   5873  O O   . THR B 1 278 ? 158.324 166.110 134.399 1.00 41.24  ? 278 THR B O   1 
ATOM   5874  C CB  . THR B 1 278 ? 159.768 166.447 131.907 1.00 41.24  ? 278 THR B CB  1 
ATOM   5875  O OG1 . THR B 1 278 ? 159.995 166.679 130.512 1.00 41.24  ? 278 THR B OG1 1 
ATOM   5876  C CG2 . THR B 1 278 ? 161.015 165.836 132.520 1.00 41.24  ? 278 THR B CG2 1 
ATOM   5877  N N   . CYS B 1 279 ? 158.122 163.935 133.870 1.00 42.00  ? 279 CYS B N   1 
ATOM   5878  C CA  . CYS B 1 279 ? 157.909 163.470 135.238 1.00 42.00  ? 279 CYS B CA  1 
ATOM   5879  C C   . CYS B 1 279 ? 158.072 161.954 135.238 1.00 42.00  ? 279 CYS B C   1 
ATOM   5880  O O   . CYS B 1 279 ? 158.313 161.338 134.196 1.00 42.00  ? 279 CYS B O   1 
ATOM   5881  C CB  . CYS B 1 279 ? 156.538 163.889 135.775 1.00 42.00  ? 279 CYS B CB  1 
ATOM   5882  S SG  . CYS B 1 279 ? 155.160 163.653 134.628 1.00 42.00  ? 279 CYS B SG  1 
ATOM   5883  N N   . ILE B 1 280 ? 157.933 161.354 136.418 1.00 39.07  ? 280 ILE B N   1 
ATOM   5884  C CA  . ILE B 1 280 ? 158.104 159.918 136.603 1.00 39.07  ? 280 ILE B CA  1 
ATOM   5885  C C   . ILE B 1 280 ? 156.801 159.332 137.126 1.00 39.07  ? 280 ILE B C   1 
ATOM   5886  O O   . ILE B 1 280 ? 156.245 159.824 138.114 1.00 39.07  ? 280 ILE B O   1 
ATOM   5887  C CB  . ILE B 1 280 ? 159.264 159.602 137.564 1.00 39.07  ? 280 ILE B CB  1 
ATOM   5888  C CG1 . ILE B 1 280 ? 160.544 160.300 137.101 1.00 39.07  ? 280 ILE B CG1 1 
ATOM   5889  C CG2 . ILE B 1 280 ? 159.471 158.099 137.668 1.00 39.07  ? 280 ILE B CG2 1 
ATOM   5890  C CD1 . ILE B 1 280 ? 161.796 159.766 137.748 1.00 39.07  ? 280 ILE B CD1 1 
ATOM   5891  N N   . SER B 1 281 ? 156.323 158.278 136.467 1.00 36.57  ? 281 SER B N   1 
ATOM   5892  C CA  . SER B 1 281 ? 155.111 157.588 136.880 1.00 36.57  ? 281 SER B CA  1 
ATOM   5893  C C   . SER B 1 281 ? 155.072 156.225 136.207 1.00 36.57  ? 281 SER B C   1 
ATOM   5894  O O   . SER B 1 281 ? 155.414 156.100 135.029 1.00 36.57  ? 281 SER B O   1 
ATOM   5895  C CB  . SER B 1 281 ? 153.857 158.395 136.527 1.00 36.57  ? 281 SER B CB  1 
ATOM   5896  O OG  . SER B 1 281 ? 152.726 157.914 137.230 1.00 36.57  ? 281 SER B OG  1 
ATOM   5897  N N   . GLU B 1 282 ? 154.651 155.212 136.958 1.00 36.28  ? 282 GLU B N   1 
ATOM   5898  C CA  . GLU B 1 282 ? 154.627 153.843 136.463 1.00 36.28  ? 282 GLU B CA  1 
ATOM   5899  C C   . GLU B 1 282 ? 153.294 153.434 135.845 1.00 36.28  ? 282 GLU B C   1 
ATOM   5900  O O   . GLU B 1 282 ? 153.247 152.415 135.150 1.00 36.28  ? 282 GLU B O   1 
ATOM   5901  C CB  . GLU B 1 282 ? 154.976 152.869 137.592 1.00 36.28  ? 282 GLU B CB  1 
ATOM   5902  C CG  . GLU B 1 282 ? 156.422 152.939 138.052 1.00 36.28  ? 282 GLU B CG  1 
ATOM   5903  C CD  . GLU B 1 282 ? 157.315 151.956 137.323 1.00 36.28  ? 282 GLU B CD  1 
ATOM   5904  O OE1 . GLU B 1 282 ? 156.805 151.211 136.460 1.00 36.28  ? 282 GLU B OE1 1 
ATOM   5905  O OE2 . GLU B 1 282 ? 158.530 151.926 137.613 1.00 36.28  ? 282 GLU B OE2 1 
ATOM   5906  N N   . CYS B 1 283 ? 152.217 154.186 136.070 1.00 32.45  ? 283 CYS B N   1 
ATOM   5907  C CA  . CYS B 1 283 ? 150.890 153.811 135.591 1.00 32.45  ? 283 CYS B CA  1 
ATOM   5908  C C   . CYS B 1 283 ? 150.305 154.928 134.739 1.00 32.45  ? 283 CYS B C   1 
ATOM   5909  O O   . CYS B 1 283 ? 150.139 156.058 135.215 1.00 32.45  ? 283 CYS B O   1 
ATOM   5910  C CB  . CYS B 1 283 ? 149.952 153.485 136.754 1.00 32.45  ? 283 CYS B CB  1 
ATOM   5911  S SG  . CYS B 1 283 ? 148.292 153.000 136.225 1.00 32.45  ? 283 CYS B SG  1 
ATOM   5912  N N   . ILE B 1 284 ? 149.948 154.588 133.500 1.00 29.19  ? 284 ILE B N   1 
ATOM   5913  C CA  . ILE B 1 284 ? 149.396 155.512 132.516 1.00 29.19  ? 284 ILE B CA  1 
ATOM   5914  C C   . ILE B 1 284 ? 147.975 155.080 132.176 1.00 29.19  ? 284 ILE B C   1 
ATOM   5915  O O   . ILE B 1 284 ? 147.716 153.890 131.970 1.00 29.19  ? 284 ILE B O   1 
ATOM   5916  C CB  . ILE B 1 284 ? 150.265 155.550 131.239 1.00 29.19  ? 284 ILE B CB  1 
ATOM   5917  C CG1 . ILE B 1 284 ? 151.682 156.029 131.562 1.00 29.19  ? 284 ILE B CG1 1 
ATOM   5918  C CG2 . ILE B 1 284 ? 149.616 156.408 130.158 1.00 29.19  ? 284 ILE B CG2 1 
ATOM   5919  C CD1 . ILE B 1 284 ? 152.717 155.589 130.554 1.00 29.19  ? 284 ILE B CD1 1 
ATOM   5920  N N   . THR B 1 285 ? 147.061 156.041 132.115 1.00 27.79  ? 285 THR B N   1 
ATOM   5921  C CA  . THR B 1 285 ? 145.690 155.856 131.666 1.00 27.79  ? 285 THR B CA  1 
ATOM   5922  C C   . THR B 1 285 ? 145.395 156.916 130.621 1.00 27.79  ? 285 THR B C   1 
ATOM   5923  O O   . THR B 1 285 ? 146.149 157.883 130.475 1.00 27.79  ? 285 THR B O   1 
ATOM   5924  C CB  . THR B 1 285 ? 144.694 155.970 132.839 1.00 27.79  ? 285 THR B CB  1 
ATOM   5925  O OG1 . THR B 1 285 ? 144.500 157.347 133.178 1.00 27.79  ? 285 THR B OG1 1 
ATOM   5926  C CG2 . THR B 1 285 ? 145.192 155.217 134.062 1.00 27.79  ? 285 THR B CG2 1 
ATOM   5927  N N   . PRO B 1 286 ? 144.309 156.763 129.857 1.00 27.64  ? 286 PRO B N   1 
ATOM   5928  C CA  . PRO B 1 286 ? 143.933 157.828 128.912 1.00 27.64  ? 286 PRO B CA  1 
ATOM   5929  C C   . PRO B 1 286 ? 143.650 159.166 129.576 1.00 27.64  ? 286 PRO B C   1 
ATOM   5930  O O   . PRO B 1 286 ? 143.682 160.193 128.891 1.00 27.64  ? 286 PRO B O   1 
ATOM   5931  C CB  . PRO B 1 286 ? 142.679 157.267 128.229 1.00 27.64  ? 286 PRO B CB  1 
ATOM   5932  C CG  . PRO B 1 286 ? 142.807 155.801 128.358 1.00 27.64  ? 286 PRO B CG  1 
ATOM   5933  C CD  . PRO B 1 286 ? 143.495 155.550 129.662 1.00 27.64  ? 286 PRO B CD  1 
ATOM   5934  N N   . ASN B 1 287 ? 143.369 159.190 130.879 1.00 30.84  ? 287 ASN B N   1 
ATOM   5935  C CA  . ASN B 1 287 ? 143.195 160.443 131.602 1.00 30.84  ? 287 ASN B CA  1 
ATOM   5936  C C   . ASN B 1 287 ? 144.514 161.071 132.033 1.00 30.84  ? 287 ASN B C   1 
ATOM   5937  O O   . ASN B 1 287 ? 144.517 162.235 132.441 1.00 30.84  ? 287 ASN B O   1 
ATOM   5938  C CB  . ASN B 1 287 ? 142.325 160.232 132.844 1.00 30.84  ? 287 ASN B CB  1 
ATOM   5939  C CG  . ASN B 1 287 ? 141.026 159.519 132.540 1.00 30.84  ? 287 ASN B CG  1 
ATOM   5940  O OD1 . ASN B 1 287 ? 141.023 158.392 132.052 1.00 30.84  ? 287 ASN B OD1 1 
ATOM   5941  N ND2 . ASN B 1 287 ? 139.909 160.173 132.838 1.00 30.84  ? 287 ASN B ND2 1 
ATOM   5942  N N   . GLY B 1 288 ? 145.623 160.338 131.961 1.00 29.53  ? 288 GLY B N   1 
ATOM   5943  C CA  . GLY B 1 288 ? 146.910 160.787 132.440 1.00 29.53  ? 288 GLY B CA  1 
ATOM   5944  C C   . GLY B 1 288 ? 147.550 159.743 133.325 1.00 29.53  ? 288 GLY B C   1 
ATOM   5945  O O   . GLY B 1 288 ? 147.071 158.613 133.449 1.00 29.53  ? 288 GLY B O   1 
ATOM   5946  N N   . SER B 1 289 ? 148.670 160.107 133.934 1.00 31.24  ? 289 SER B N   1 
ATOM   5947  C CA  . SER B 1 289 ? 149.351 159.195 134.839 1.00 31.24  ? 289 SER B CA  1 
ATOM   5948  C C   . SER B 1 289 ? 148.692 159.214 136.212 1.00 31.24  ? 289 SER B C   1 
ATOM   5949  O O   . SER B 1 289 ? 148.130 160.225 136.639 1.00 31.24  ? 289 SER B O   1 
ATOM   5950  C CB  . SER B 1 289 ? 150.828 159.565 134.959 1.00 31.24  ? 289 SER B CB  1 
ATOM   5951  O OG  . SER B 1 289 ? 151.527 159.234 133.777 1.00 31.24  ? 289 SER B OG  1 
ATOM   5952  N N   . ILE B 1 290 ? 148.750 158.077 136.900 1.00 31.43  ? 290 ILE B N   1 
ATOM   5953  C CA  . ILE B 1 290 ? 148.210 158.014 138.260 1.00 31.43  ? 290 ILE B CA  1 
ATOM   5954  C C   . ILE B 1 290 ? 149.202 157.331 139.195 1.00 31.43  ? 290 ILE B C   1 
ATOM   5955  O O   . ILE B 1 290 ? 149.919 156.411 138.777 1.00 31.43  ? 290 ILE B O   1 
ATOM   5956  C CB  . ILE B 1 290 ? 146.846 157.301 138.304 1.00 31.43  ? 290 ILE B CB  1 
ATOM   5957  C CG1 . ILE B 1 290 ? 146.947 155.880 137.751 1.00 31.43  ? 290 ILE B CG1 1 
ATOM   5958  C CG2 . ILE B 1 290 ? 145.779 158.101 137.568 1.00 31.43  ? 290 ILE B CG2 1 
ATOM   5959  C CD1 . ILE B 1 290 ? 145.718 155.042 138.015 1.00 31.43  ? 290 ILE B CD1 1 
ATOM   5960  N N   . PRO B 1 291 ? 149.285 157.753 140.457 1.00 32.95  ? 291 PRO B N   1 
ATOM   5961  C CA  . PRO B 1 291 ? 150.113 157.029 141.426 1.00 32.95  ? 291 PRO B CA  1 
ATOM   5962  C C   . PRO B 1 291 ? 149.534 155.657 141.729 1.00 32.95  ? 291 PRO B C   1 
ATOM   5963  O O   . PRO B 1 291 ? 148.324 155.437 141.649 1.00 32.95  ? 291 PRO B O   1 
ATOM   5964  C CB  . PRO B 1 291 ? 150.085 157.933 142.664 1.00 32.95  ? 291 PRO B CB  1 
ATOM   5965  C CG  . PRO B 1 291 ? 148.849 158.743 142.517 1.00 32.95  ? 291 PRO B CG  1 
ATOM   5966  C CD  . PRO B 1 291 ? 148.638 158.937 141.048 1.00 32.95  ? 291 PRO B CD  1 
ATOM   5967  N N   . ASN B 1 292 ? 150.416 154.722 142.081 1.00 35.46  ? 292 ASN B N   1 
ATOM   5968  C CA  . ASN B 1 292 ? 150.018 153.335 142.288 1.00 35.46  ? 292 ASN B CA  1 
ATOM   5969  C C   . ASN B 1 292 ? 150.244 152.863 143.724 1.00 35.46  ? 292 ASN B C   1 
ATOM   5970  O O   . ASN B 1 292 ? 150.450 151.672 143.960 1.00 35.46  ? 292 ASN B O   1 
ATOM   5971  C CB  . ASN B 1 292 ? 150.739 152.412 141.305 1.00 35.46  ? 292 ASN B CB  1 
ATOM   5972  C CG  . ASN B 1 292 ? 152.249 152.434 141.468 1.00 35.46  ? 292 ASN B CG  1 
ATOM   5973  O OD1 . ASN B 1 292 ? 152.791 153.182 142.279 1.00 35.46  ? 292 ASN B OD1 1 
ATOM   5974  N ND2 . ASN B 1 292 ? 152.934 151.596 140.702 1.00 35.46  ? 292 ASN B ND2 1 
ATOM   5975  N N   . ASP B 1 293 ? 150.196 153.773 144.699 1.00 35.88  ? 293 ASP B N   1 
ATOM   5976  C CA  . ASP B 1 293 ? 150.337 153.351 146.089 1.00 35.88  ? 293 ASP B CA  1 
ATOM   5977  C C   . ASP B 1 293 ? 149.060 152.740 146.656 1.00 35.88  ? 293 ASP B C   1 
ATOM   5978  O O   . ASP B 1 293 ? 149.126 152.032 147.664 1.00 35.88  ? 293 ASP B O   1 
ATOM   5979  C CB  . ASP B 1 293 ? 150.782 154.523 146.969 1.00 35.88  ? 293 ASP B CB  1 
ATOM   5980  C CG  . ASP B 1 293 ? 150.102 155.823 146.604 1.00 35.88  ? 293 ASP B CG  1 
ATOM   5981  O OD1 . ASP B 1 293 ? 148.866 155.916 146.751 1.00 35.88  ? 293 ASP B OD1 1 
ATOM   5982  O OD2 . ASP B 1 293 ? 150.806 156.760 146.177 1.00 35.88  ? 293 ASP B OD2 1 
ATOM   5983  N N   . LYS B 1 294 ? 147.913 152.986 146.038 1.00 31.71  ? 294 LYS B N   1 
ATOM   5984  C CA  . LYS B 1 294 ? 146.676 152.371 146.493 1.00 31.71  ? 294 LYS B CA  1 
ATOM   5985  C C   . LYS B 1 294 ? 146.380 151.104 145.695 1.00 31.71  ? 294 LYS B C   1 
ATOM   5986  O O   . LYS B 1 294 ? 146.778 150.989 144.533 1.00 31.71  ? 294 LYS B O   1 
ATOM   5987  C CB  . LYS B 1 294 ? 145.514 153.351 146.357 1.00 31.71  ? 294 LYS B CB  1 
ATOM   5988  C CG  . LYS B 1 294 ? 145.545 154.477 147.375 1.00 31.71  ? 294 LYS B CG  1 
ATOM   5989  C CD  . LYS B 1 294 ? 144.521 155.550 147.062 1.00 31.71  ? 294 LYS B CD  1 
ATOM   5990  C CE  . LYS B 1 294 ? 144.879 156.858 147.745 1.00 31.71  ? 294 LYS B CE  1 
ATOM   5991  N NZ  . LYS B 1 294 ? 143.701 157.750 147.900 1.00 31.71  ? 294 LYS B NZ  1 
ATOM   5992  N N   . PRO B 1 295 ? 145.693 150.126 146.296 1.00 28.68  ? 295 PRO B N   1 
ATOM   5993  C CA  . PRO B 1 295 ? 145.423 148.871 145.575 1.00 28.68  ? 295 PRO B CA  1 
ATOM   5994  C C   . PRO B 1 295 ? 144.322 148.959 144.529 1.00 28.68  ? 295 PRO B C   1 
ATOM   5995  O O   . PRO B 1 295 ? 144.253 148.075 143.665 1.00 28.68  ? 295 PRO B O   1 
ATOM   5996  C CB  . PRO B 1 295 ? 145.030 147.901 146.699 1.00 28.68  ? 295 PRO B CB  1 
ATOM   5997  C CG  . PRO B 1 295 ? 144.506 148.776 147.778 1.00 28.68  ? 295 PRO B CG  1 
ATOM   5998  C CD  . PRO B 1 295 ? 145.316 150.037 147.717 1.00 28.68  ? 295 PRO B CD  1 
ATOM   5999  N N   . PHE B 1 296 ? 143.465 149.977 144.569 1.00 27.12  ? 296 PHE B N   1 
ATOM   6000  C CA  . PHE B 1 296 ? 142.340 150.087 143.652 1.00 27.12  ? 296 PHE B CA  1 
ATOM   6001  C C   . PHE B 1 296 ? 142.288 151.487 143.055 1.00 27.12  ? 296 PHE B C   1 
ATOM   6002  O O   . PHE B 1 296 ? 142.800 152.449 143.629 1.00 27.12  ? 296 PHE B O   1 
ATOM   6003  C CB  . PHE B 1 296 ? 141.010 149.769 144.351 1.00 27.12  ? 296 PHE B CB  1 
ATOM   6004  C CG  . PHE B 1 296 ? 141.009 148.464 145.095 1.00 27.12  ? 296 PHE B CG  1 
ATOM   6005  C CD1 . PHE B 1 296 ? 141.100 147.264 144.417 1.00 27.12  ? 296 PHE B CD1 1 
ATOM   6006  C CD2 . PHE B 1 296 ? 140.911 148.440 146.475 1.00 27.12  ? 296 PHE B CD2 1 
ATOM   6007  C CE1 . PHE B 1 296 ? 141.100 146.067 145.098 1.00 27.12  ? 296 PHE B CE1 1 
ATOM   6008  C CE2 . PHE B 1 296 ? 140.909 147.242 147.161 1.00 27.12  ? 296 PHE B CE2 1 
ATOM   6009  C CZ  . PHE B 1 296 ? 141.005 146.056 146.471 1.00 27.12  ? 296 PHE B CZ  1 
ATOM   6010  N N   . GLN B 1 297 ? 141.657 151.587 141.886 1.00 25.48  ? 297 GLN B N   1 
ATOM   6011  C CA  . GLN B 1 297 ? 141.494 152.859 141.198 1.00 25.48  ? 297 GLN B CA  1 
ATOM   6012  C C   . GLN B 1 297 ? 140.131 152.902 140.521 1.00 25.48  ? 297 GLN B C   1 
ATOM   6013  O O   . GLN B 1 297 ? 139.521 151.872 140.230 1.00 25.48  ? 297 GLN B O   1 
ATOM   6014  C CB  . GLN B 1 297 ? 142.611 153.106 140.171 1.00 25.48  ? 297 GLN B CB  1 
ATOM   6015  C CG  . GLN B 1 297 ? 142.800 151.990 139.157 1.00 25.48  ? 297 GLN B CG  1 
ATOM   6016  C CD  . GLN B 1 297 ? 142.180 152.309 137.809 1.00 25.48  ? 297 GLN B CD  1 
ATOM   6017  O OE1 . GLN B 1 297 ? 141.544 153.344 137.636 1.00 25.48  ? 297 GLN B OE1 1 
ATOM   6018  N NE2 . GLN B 1 297 ? 142.360 151.413 136.850 1.00 25.48  ? 297 GLN B NE2 1 
ATOM   6019  N N   . ASN B 1 298 ? 139.662 154.124 140.274 1.00 26.53  ? 298 ASN B N   1 
ATOM   6020  C CA  . ASN B 1 298 ? 138.355 154.368 139.681 1.00 26.53  ? 298 ASN B CA  1 
ATOM   6021  C C   . ASN B 1 298 ? 138.440 155.270 138.454 1.00 26.53  ? 298 ASN B C   1 
ATOM   6022  O O   . ASN B 1 298 ? 137.402 155.709 137.948 1.00 26.53  ? 298 ASN B O   1 
ATOM   6023  C CB  . ASN B 1 298 ? 137.417 154.984 140.728 1.00 26.53  ? 298 ASN B CB  1 
ATOM   6024  C CG  . ASN B 1 298 ? 135.963 154.886 140.344 1.00 26.53  ? 298 ASN B CG  1 
ATOM   6025  O OD1 . ASN B 1 298 ? 135.522 153.884 139.785 1.00 26.53  ? 298 ASN B OD1 1 
ATOM   6026  N ND2 . ASN B 1 298 ? 135.204 155.931 140.643 1.00 26.53  ? 298 ASN B ND2 1 
ATOM   6027  N N   . VAL B 1 299 ? 139.643 155.544 137.954 1.00 26.77  ? 299 VAL B N   1 
ATOM   6028  C CA  . VAL B 1 299 ? 139.808 156.545 136.905 1.00 26.77  ? 299 VAL B CA  1 
ATOM   6029  C C   . VAL B 1 299 ? 139.420 155.983 135.541 1.00 26.77  ? 299 VAL B C   1 
ATOM   6030  O O   . VAL B 1 299 ? 138.585 156.559 134.836 1.00 26.77  ? 299 VAL B O   1 
ATOM   6031  C CB  . VAL B 1 299 ? 141.253 157.079 136.913 1.00 26.77  ? 299 VAL B CB  1 
ATOM   6032  C CG1 . VAL B 1 299 ? 141.452 158.100 135.809 1.00 26.77  ? 299 VAL B CG1 1 
ATOM   6033  C CG2 . VAL B 1 299 ? 141.583 157.683 138.270 1.00 26.77  ? 299 VAL B CG2 1 
ATOM   6034  N N   . ASN B 1 300 ? 140.011 154.858 135.148 1.00 25.62  ? 300 ASN B N   1 
ATOM   6035  C CA  . ASN B 1 300 ? 139.785 154.310 133.817 1.00 25.62  ? 300 ASN B CA  1 
ATOM   6036  C C   . ASN B 1 300 ? 140.138 152.831 133.812 1.00 25.62  ? 300 ASN B C   1 
ATOM   6037  O O   . ASN B 1 300 ? 141.120 152.423 134.433 1.00 25.62  ? 300 ASN B O   1 
ATOM   6038  C CB  . ASN B 1 300 ? 140.620 155.051 132.764 1.00 25.62  ? 300 ASN B CB  1 
ATOM   6039  C CG  . ASN B 1 300 ? 139.990 155.019 131.388 1.00 25.62  ? 300 ASN B CG  1 
ATOM   6040  O OD1 . ASN B 1 300 ? 139.690 153.955 130.854 1.00 25.62  ? 300 ASN B OD1 1 
ATOM   6041  N ND2 . ASN B 1 300 ? 139.788 156.191 130.807 1.00 25.62  ? 300 ASN B ND2 1 
ATOM   6042  N N   . LYS B 1 301 ? 139.346 152.038 133.092 1.00 26.09  ? 301 LYS B N   1 
ATOM   6043  C CA  . LYS B 1 301 ? 139.640 150.618 132.952 1.00 26.09  ? 301 LYS B CA  1 
ATOM   6044  C C   . LYS B 1 301 ? 140.696 150.329 131.891 1.00 26.09  ? 301 LYS B C   1 
ATOM   6045  O O   . LYS B 1 301 ? 141.104 149.173 131.751 1.00 26.09  ? 301 LYS B O   1 
ATOM   6046  C CB  . LYS B 1 301 ? 138.361 149.836 132.641 1.00 26.09  ? 301 LYS B CB  1 
ATOM   6047  C CG  . LYS B 1 301 ? 137.700 150.184 131.324 1.00 26.09  ? 301 LYS B CG  1 
ATOM   6048  C CD  . LYS B 1 301 ? 136.299 149.600 131.256 1.00 26.09  ? 301 LYS B CD  1 
ATOM   6049  C CE  . LYS B 1 301 ? 135.709 149.727 129.861 1.00 26.09  ? 301 LYS B CE  1 
ATOM   6050  N NZ  . LYS B 1 301 ? 134.820 150.914 129.728 1.00 26.09  ? 301 LYS B NZ  1 
ATOM   6051  N N   . ILE B 1 302 ? 141.145 151.338 131.151 1.00 25.59  ? 302 ILE B N   1 
ATOM   6052  C CA  . ILE B 1 302 ? 142.247 151.208 130.205 1.00 25.59  ? 302 ILE B CA  1 
ATOM   6053  C C   . ILE B 1 302 ? 143.519 151.670 130.903 1.00 25.59  ? 302 ILE B C   1 
ATOM   6054  O O   . ILE B 1 302 ? 143.608 152.821 131.343 1.00 25.59  ? 302 ILE B O   1 
ATOM   6055  C CB  . ILE B 1 302 ? 141.987 152.022 128.928 1.00 25.59  ? 302 ILE B CB  1 
ATOM   6056  C CG1 . ILE B 1 302 ? 140.835 151.408 128.132 1.00 25.59  ? 302 ILE B CG1 1 
ATOM   6057  C CG2 . ILE B 1 302 ? 143.243 152.113 128.080 1.00 25.59  ? 302 ILE B CG2 1 
ATOM   6058  C CD1 . ILE B 1 302 ? 140.127 152.387 127.232 1.00 25.59  ? 302 ILE B CD1 1 
ATOM   6059  N N   . THR B 1 303 ? 144.504 150.779 131.014 1.00 27.96  ? 303 THR B N   1 
ATOM   6060  C CA  . THR B 1 303 ? 145.726 151.073 131.754 1.00 27.96  ? 303 THR B CA  1 
ATOM   6061  C C   . THR B 1 303 ? 146.926 150.451 131.053 1.00 27.96  ? 303 THR B C   1 
ATOM   6062  O O   . THR B 1 303 ? 146.798 149.508 130.270 1.00 27.96  ? 303 THR B O   1 
ATOM   6063  C CB  . THR B 1 303 ? 145.664 150.558 133.207 1.00 27.96  ? 303 THR B CB  1 
ATOM   6064  O OG1 . THR B 1 303 ? 145.211 149.199 133.223 1.00 27.96  ? 303 THR B OG1 1 
ATOM   6065  C CG2 . THR B 1 303 ? 144.731 151.410 134.057 1.00 27.96  ? 303 THR B CG2 1 
ATOM   6066  N N   . TYR B 1 304 ? 148.102 151.000 131.351 1.00 28.95  ? 304 TYR B N   1 
ATOM   6067  C CA  . TYR B 1 304 ? 149.373 150.450 130.900 1.00 28.95  ? 304 TYR B CA  1 
ATOM   6068  C C   . TYR B 1 304 ? 150.390 150.594 132.022 1.00 28.95  ? 304 TYR B C   1 
ATOM   6069  O O   . TYR B 1 304 ? 150.522 151.676 132.600 1.00 28.95  ? 304 TYR B O   1 
ATOM   6070  C CB  . TYR B 1 304 ? 149.875 151.158 129.634 1.00 28.95  ? 304 TYR B CB  1 
ATOM   6071  C CG  . TYR B 1 304 ? 151.185 150.614 129.106 1.00 28.95  ? 304 TYR B CG  1 
ATOM   6072  C CD1 . TYR B 1 304 ? 151.209 149.515 128.260 1.00 28.95  ? 304 TYR B CD1 1 
ATOM   6073  C CD2 . TYR B 1 304 ? 152.396 151.198 129.454 1.00 28.95  ? 304 TYR B CD2 1 
ATOM   6074  C CE1 . TYR B 1 304 ? 152.397 149.012 127.775 1.00 28.95  ? 304 TYR B CE1 1 
ATOM   6075  C CE2 . TYR B 1 304 ? 153.593 150.698 128.977 1.00 28.95  ? 304 TYR B CE2 1 
ATOM   6076  C CZ  . TYR B 1 304 ? 153.586 149.605 128.137 1.00 28.95  ? 304 TYR B CZ  1 
ATOM   6077  O OH  . TYR B 1 304 ? 154.768 149.100 127.653 1.00 28.95  ? 304 TYR B OH  1 
ATOM   6078  N N   . GLY B 1 305 ? 151.105 149.513 132.324 1.00 32.09  ? 305 GLY B N   1 
ATOM   6079  C CA  . GLY B 1 305 ? 152.137 149.546 133.344 1.00 32.09  ? 305 GLY B CA  1 
ATOM   6080  C C   . GLY B 1 305 ? 151.760 148.852 134.639 1.00 32.09  ? 305 GLY B C   1 
ATOM   6081  O O   . GLY B 1 305 ? 150.947 147.924 134.639 1.00 32.09  ? 305 GLY B O   1 
ATOM   6082  N N   . ALA B 1 306 ? 152.350 149.292 135.749 1.00 34.32  ? 306 ALA B N   1 
ATOM   6083  C CA  . ALA B 1 306 ? 152.052 148.752 137.077 1.00 34.32  ? 306 ALA B CA  1 
ATOM   6084  C C   . ALA B 1 306 ? 150.938 149.593 137.687 1.00 34.32  ? 306 ALA B C   1 
ATOM   6085  O O   . ALA B 1 306 ? 151.170 150.711 138.148 1.00 34.32  ? 306 ALA B O   1 
ATOM   6086  C CB  . ALA B 1 306 ? 153.298 148.754 137.954 1.00 34.32  ? 306 ALA B CB  1 
ATOM   6087  N N   . CYS B 1 307 ? 149.726 149.052 137.699 1.00 32.37  ? 307 CYS B N   1 
ATOM   6088  C CA  . CYS B 1 307 ? 148.547 149.848 137.992 1.00 32.37  ? 307 CYS B CA  1 
ATOM   6089  C C   . CYS B 1 307 ? 147.676 149.182 139.045 1.00 32.37  ? 307 CYS B C   1 
ATOM   6090  O O   . CYS B 1 307 ? 147.687 147.956 139.187 1.00 32.37  ? 307 CYS B O   1 
ATOM   6091  C CB  . CYS B 1 307 ? 147.721 150.074 136.718 1.00 32.37  ? 307 CYS B CB  1 
ATOM   6092  S SG  . CYS B 1 307 ? 148.524 151.124 135.486 1.00 32.37  ? 307 CYS B SG  1 
ATOM   6093  N N   . PRO B 1 308 ? 146.917 149.970 139.801 1.00 28.80  ? 308 PRO B N   1 
ATOM   6094  C CA  . PRO B 1 308 ? 145.897 149.394 140.683 1.00 28.80  ? 308 PRO B CA  1 
ATOM   6095  C C   . PRO B 1 308 ? 144.751 148.791 139.886 1.00 28.80  ? 308 PRO B C   1 
ATOM   6096  O O   . PRO B 1 308 ? 144.500 149.146 138.733 1.00 28.80  ? 308 PRO B O   1 
ATOM   6097  C CB  . PRO B 1 308 ? 145.420 150.590 141.517 1.00 28.80  ? 308 PRO B CB  1 
ATOM   6098  C CG  . PRO B 1 308 ? 146.436 151.664 141.301 1.00 28.80  ? 308 PRO B CG  1 
ATOM   6099  C CD  . PRO B 1 308 ? 147.031 151.428 139.959 1.00 28.80  ? 308 PRO B CD  1 
ATOM   6100  N N   . LYS B 1 309 ? 144.052 147.858 140.523 1.00 28.40  ? 309 LYS B N   1 
ATOM   6101  C CA  . LYS B 1 309 ? 142.920 147.204 139.883 1.00 28.40  ? 309 LYS B CA  1 
ATOM   6102  C C   . LYS B 1 309 ? 141.725 148.146 139.799 1.00 28.40  ? 309 LYS B C   1 
ATOM   6103  O O   . LYS B 1 309 ? 141.425 148.883 140.741 1.00 28.40  ? 309 LYS B O   1 
ATOM   6104  C CB  . LYS B 1 309 ? 142.537 145.941 140.649 1.00 28.40  ? 309 LYS B CB  1 
ATOM   6105  C CG  . LYS B 1 309 ? 143.660 144.935 140.769 1.00 28.40  ? 309 LYS B CG  1 
ATOM   6106  C CD  . LYS B 1 309 ? 143.176 143.637 141.376 1.00 28.40  ? 309 LYS B CD  1 
ATOM   6107  C CE  . LYS B 1 309 ? 144.326 142.668 141.576 1.00 28.40  ? 309 LYS B CE  1 
ATOM   6108  N NZ  . LYS B 1 309 ? 145.220 143.091 142.685 1.00 28.40  ? 309 LYS B NZ  1 
ATOM   6109  N N   . TYR B 1 310 ? 141.035 148.112 138.663 1.00 24.35  ? 310 TYR B N   1 
ATOM   6110  C CA  . TYR B 1 310 ? 139.879 148.972 138.453 1.00 24.35  ? 310 TYR B CA  1 
ATOM   6111  C C   . TYR B 1 310 ? 138.661 148.421 139.186 1.00 24.35  ? 310 TYR B C   1 
ATOM   6112  O O   . TYR B 1 310 ? 138.382 147.221 139.127 1.00 24.35  ? 310 TYR B O   1 
ATOM   6113  C CB  . TYR B 1 310 ? 139.580 149.110 136.960 1.00 24.35  ? 310 TYR B CB  1 
ATOM   6114  C CG  . TYR B 1 310 ? 138.396 149.998 136.664 1.00 24.35  ? 310 TYR B CG  1 
ATOM   6115  C CD1 . TYR B 1 310 ? 138.518 151.379 136.684 1.00 24.35  ? 310 TYR B CD1 1 
ATOM   6116  C CD2 . TYR B 1 310 ? 137.153 149.455 136.379 1.00 24.35  ? 310 TYR B CD2 1 
ATOM   6117  C CE1 . TYR B 1 310 ? 137.437 152.193 136.420 1.00 24.35  ? 310 TYR B CE1 1 
ATOM   6118  C CE2 . TYR B 1 310 ? 136.066 150.260 136.116 1.00 24.35  ? 310 TYR B CE2 1 
ATOM   6119  C CZ  . TYR B 1 310 ? 136.214 151.627 136.136 1.00 24.35  ? 310 TYR B CZ  1 
ATOM   6120  O OH  . TYR B 1 310 ? 135.130 152.428 135.876 1.00 24.35  ? 310 TYR B OH  1 
ATOM   6121  N N   . VAL B 1 311 ? 137.940 149.302 139.879 1.00 24.43  ? 311 VAL B N   1 
ATOM   6122  C CA  . VAL B 1 311 ? 136.699 148.956 140.562 1.00 24.43  ? 311 VAL B CA  1 
ATOM   6123  C C   . VAL B 1 311 ? 135.670 150.040 140.268 1.00 24.43  ? 311 VAL B C   1 
ATOM   6124  O O   . VAL B 1 311 ? 135.993 151.117 139.768 1.00 24.43  ? 311 VAL B O   1 
ATOM   6125  C CB  . VAL B 1 311 ? 136.880 148.785 142.088 1.00 24.43  ? 311 VAL B CB  1 
ATOM   6126  C CG1 . VAL B 1 311 ? 137.716 147.556 142.396 1.00 24.43  ? 311 VAL B CG1 1 
ATOM   6127  C CG2 . VAL B 1 311 ? 137.499 150.032 142.707 1.00 24.43  ? 311 VAL B CG2 1 
ATOM   6128  N N   . LYS B 1 312 ? 134.414 149.738 140.589 1.00 27.73  ? 312 LYS B N   1 
ATOM   6129  C CA  . LYS B 1 312 ? 133.312 150.665 140.362 1.00 27.73  ? 312 LYS B CA  1 
ATOM   6130  C C   . LYS B 1 312 ? 133.121 151.668 141.493 1.00 27.73  ? 312 LYS B C   1 
ATOM   6131  O O   . LYS B 1 312 ? 132.600 152.761 141.253 1.00 27.73  ? 312 LYS B O   1 
ATOM   6132  C CB  . LYS B 1 312 ? 132.010 149.889 140.152 1.00 27.73  ? 312 LYS B CB  1 
ATOM   6133  C CG  . LYS B 1 312 ? 131.672 149.633 138.698 1.00 27.73  ? 312 LYS B CG  1 
ATOM   6134  C CD  . LYS B 1 312 ? 131.087 148.249 138.494 1.00 27.73  ? 312 LYS B CD  1 
ATOM   6135  C CE  . LYS B 1 312 ? 129.921 147.990 139.423 1.00 27.73  ? 312 LYS B CE  1 
ATOM   6136  N NZ  . LYS B 1 312 ? 129.780 146.543 139.735 1.00 27.73  ? 312 LYS B NZ  1 
ATOM   6137  N N   . GLN B 1 313 ? 133.516 151.323 142.716 1.00 28.69  ? 313 GLN B N   1 
ATOM   6138  C CA  . GLN B 1 313 ? 133.305 152.208 143.855 1.00 28.69  ? 313 GLN B CA  1 
ATOM   6139  C C   . GLN B 1 313 ? 134.238 153.413 143.791 1.00 28.69  ? 313 GLN B C   1 
ATOM   6140  O O   . GLN B 1 313 ? 135.384 153.308 143.348 1.00 28.69  ? 313 GLN B O   1 
ATOM   6141  C CB  . GLN B 1 313 ? 133.524 151.444 145.162 1.00 28.69  ? 313 GLN B CB  1 
ATOM   6142  C CG  . GLN B 1 313 ? 132.595 150.255 145.353 1.00 28.69  ? 313 GLN B CG  1 
ATOM   6143  C CD  . GLN B 1 313 ? 133.237 148.932 144.972 1.00 28.69  ? 313 GLN B CD  1 
ATOM   6144  O OE1 . GLN B 1 313 ? 133.933 148.833 143.964 1.00 28.69  ? 313 GLN B OE1 1 
ATOM   6145  N NE2 . GLN B 1 313 ? 132.997 147.907 145.777 1.00 28.69  ? 313 GLN B NE2 1 
ATOM   6146  N N   . ASN B 1 314 ? 133.744 154.566 144.243 1.00 33.19  ? 314 ASN B N   1 
ATOM   6147  C CA  . ASN B 1 314 ? 134.570 155.766 144.274 1.00 33.19  ? 314 ASN B CA  1 
ATOM   6148  C C   . ASN B 1 314 ? 135.249 156.003 145.619 1.00 33.19  ? 314 ASN B C   1 
ATOM   6149  O O   . ASN B 1 314 ? 136.080 156.911 145.715 1.00 33.19  ? 314 ASN B O   1 
ATOM   6150  C CB  . ASN B 1 314 ? 133.749 157.005 143.879 1.00 33.19  ? 314 ASN B CB  1 
ATOM   6151  C CG  . ASN B 1 314 ? 132.539 157.227 144.767 1.00 33.19  ? 314 ASN B CG  1 
ATOM   6152  O OD1 . ASN B 1 314 ? 132.663 157.421 145.974 1.00 33.19  ? 314 ASN B OD1 1 
ATOM   6153  N ND2 . ASN B 1 314 ? 131.358 157.214 144.164 1.00 33.19  ? 314 ASN B ND2 1 
ATOM   6154  N N   . THR B 1 315 ? 134.938 155.214 146.646 1.00 32.82  ? 315 THR B N   1 
ATOM   6155  C CA  . THR B 1 315 ? 135.612 155.347 147.932 1.00 32.82  ? 315 THR B CA  1 
ATOM   6156  C C   . THR B 1 315 ? 135.476 154.053 148.724 1.00 32.82  ? 315 THR B C   1 
ATOM   6157  O O   . THR B 1 315 ? 134.436 153.393 148.675 1.00 32.82  ? 315 THR B O   1 
ATOM   6158  C CB  . THR B 1 315 ? 135.056 156.524 148.749 1.00 32.82  ? 315 THR B CB  1 
ATOM   6159  O OG1 . THR B 1 315 ? 135.683 156.553 150.036 1.00 32.82  ? 315 THR B OG1 1 
ATOM   6160  C CG2 . THR B 1 315 ? 133.549 156.402 148.928 1.00 32.82  ? 315 THR B CG2 1 
ATOM   6161  N N   . LEU B 1 316 ? 136.538 153.702 149.446 1.00 32.30  ? 316 LEU B N   1 
ATOM   6162  C CA  . LEU B 1 316 ? 136.542 152.552 150.347 1.00 32.30  ? 316 LEU B CA  1 
ATOM   6163  C C   . LEU B 1 316 ? 137.493 152.862 151.492 1.00 32.30  ? 316 LEU B C   1 
ATOM   6164  O O   . LEU B 1 316 ? 138.691 153.047 151.265 1.00 32.30  ? 316 LEU B O   1 
ATOM   6165  C CB  . LEU B 1 316 ? 136.971 151.271 149.625 1.00 32.30  ? 316 LEU B CB  1 
ATOM   6166  C CG  . LEU B 1 316 ? 135.977 150.561 148.701 1.00 32.30  ? 316 LEU B CG  1 
ATOM   6167  C CD1 . LEU B 1 316 ? 136.684 149.498 147.880 1.00 32.30  ? 316 LEU B CD1 1 
ATOM   6168  C CD2 . LEU B 1 316 ? 134.832 149.952 149.490 1.00 32.30  ? 316 LEU B CD2 1 
ATOM   6169  N N   . LYS B 1 317 ? 136.972 152.907 152.714 1.00 35.30  ? 317 LYS B N   1 
ATOM   6170  C CA  . LYS B 1 317 ? 137.751 153.302 153.881 1.00 35.30  ? 317 LYS B CA  1 
ATOM   6171  C C   . LYS B 1 317 ? 138.130 152.081 154.710 1.00 35.30  ? 317 LYS B C   1 
ATOM   6172  O O   . LYS B 1 317 ? 137.261 151.300 155.107 1.00 35.30  ? 317 LYS B O   1 
ATOM   6173  C CB  . LYS B 1 317 ? 136.969 154.298 154.738 1.00 35.30  ? 317 LYS B CB  1 
ATOM   6174  C CG  . LYS B 1 317 ? 136.415 155.476 153.961 1.00 35.30  ? 317 LYS B CG  1 
ATOM   6175  C CD  . LYS B 1 317 ? 137.525 156.404 153.502 1.00 35.30  ? 317 LYS B CD  1 
ATOM   6176  C CE  . LYS B 1 317 ? 138.054 157.245 154.650 1.00 35.30  ? 317 LYS B CE  1 
ATOM   6177  N NZ  . LYS B 1 317 ? 139.540 157.256 154.696 1.00 35.30  ? 317 LYS B NZ  1 
ATOM   6178  N N   . LEU B 1 318 ? 139.424 151.929 154.979 1.00 36.16  ? 318 LEU B N   1 
ATOM   6179  C CA  . LEU B 1 318 ? 139.950 150.844 155.798 1.00 36.16  ? 318 LEU B CA  1 
ATOM   6180  C C   . LEU B 1 318 ? 140.352 151.386 157.163 1.00 36.16  ? 318 LEU B C   1 
ATOM   6181  O O   . LEU B 1 318 ? 141.111 152.356 157.249 1.00 36.16  ? 318 LEU B O   1 
ATOM   6182  C CB  . LEU B 1 318 ? 141.150 150.177 155.121 1.00 36.16  ? 318 LEU B CB  1 
ATOM   6183  C CG  . LEU B 1 318 ? 141.776 148.993 155.861 1.00 36.16  ? 318 LEU B CG  1 
ATOM   6184  C CD1 . LEU B 1 318 ? 141.038 147.705 155.549 1.00 36.16  ? 318 LEU B CD1 1 
ATOM   6185  C CD2 . LEU B 1 318 ? 143.248 148.859 155.530 1.00 36.16  ? 318 LEU B CD2 1 
ATOM   6186  N N   . ALA B 1 319 ? 139.847 150.756 158.221 1.00 40.26  ? 319 ALA B N   1 
ATOM   6187  C CA  . ALA B 1 319 ? 140.106 151.226 159.576 1.00 40.26  ? 319 ALA B CA  1 
ATOM   6188  C C   . ALA B 1 319 ? 141.565 151.015 159.964 1.00 40.26  ? 319 ALA B C   1 
ATOM   6189  O O   . ALA B 1 319 ? 142.161 149.976 159.672 1.00 40.26  ? 319 ALA B O   1 
ATOM   6190  C CB  . ALA B 1 319 ? 139.197 150.508 160.571 1.00 40.26  ? 319 ALA B CB  1 
ATOM   6191  N N   . THR B 1 320 ? 142.132 152.011 160.645 1.00 46.85  ? 320 THR B N   1 
ATOM   6192  C CA  . THR B 1 320 ? 143.505 151.960 161.122 1.00 46.85  ? 320 THR B CA  1 
ATOM   6193  C C   . THR B 1 320 ? 143.613 152.020 162.642 1.00 46.85  ? 320 THR B C   1 
ATOM   6194  O O   . THR B 1 320 ? 144.607 151.535 163.193 1.00 46.85  ? 320 THR B O   1 
ATOM   6195  C CB  . THR B 1 320 ? 144.319 153.105 160.484 1.00 46.85  ? 320 THR B CB  1 
ATOM   6196  O OG1 . THR B 1 320 ? 144.472 152.850 159.083 1.00 46.85  ? 320 THR B OG1 1 
ATOM   6197  C CG2 . THR B 1 320 ? 145.704 153.240 161.091 1.00 46.85  ? 320 THR B CG2 1 
ATOM   6198  N N   . GLY B 1 321 ? 142.599 152.530 163.335 1.00 50.23  ? 321 GLY B N   1 
ATOM   6199  C CA  . GLY B 1 321 ? 142.607 152.552 164.784 1.00 50.23  ? 321 GLY B CA  1 
ATOM   6200  C C   . GLY B 1 321 ? 141.417 151.850 165.407 1.00 50.23  ? 321 GLY B C   1 
ATOM   6201  O O   . GLY B 1 321 ? 140.648 151.183 164.712 1.00 50.23  ? 321 GLY B O   1 
ATOM   6202  N N   . MET B 1 322 ? 141.258 151.995 166.719 1.00 55.35  ? 322 MET B N   1 
ATOM   6203  C CA  . MET B 1 322 ? 140.180 151.352 167.454 1.00 55.35  ? 322 MET B CA  1 
ATOM   6204  C C   . MET B 1 322 ? 138.898 152.176 167.344 1.00 55.35  ? 322 MET B C   1 
ATOM   6205  O O   . MET B 1 322 ? 138.875 153.266 166.770 1.00 55.35  ? 322 MET B O   1 
ATOM   6206  C CB  . MET B 1 322 ? 140.586 151.159 168.912 1.00 55.35  ? 322 MET B CB  1 
ATOM   6207  C CG  . MET B 1 322 ? 141.057 152.438 169.584 1.00 55.35  ? 322 MET B CG  1 
ATOM   6208  S SD  . MET B 1 322 ? 141.138 152.324 171.379 1.00 55.35  ? 322 MET B SD  1 
ATOM   6209  C CE  . MET B 1 322 ? 142.610 151.330 171.579 1.00 55.35  ? 322 MET B CE  1 
ATOM   6210  N N   . ARG B 1 323 ? 137.810 151.647 167.900 1.00 55.31  ? 323 ARG B N   1 
ATOM   6211  C CA  . ARG B 1 323 ? 136.554 152.383 167.919 1.00 55.31  ? 323 ARG B CA  1 
ATOM   6212  C C   . ARG B 1 323 ? 136.688 153.635 168.778 1.00 55.31  ? 323 ARG B C   1 
ATOM   6213  O O   . ARG B 1 323 ? 137.400 153.645 169.785 1.00 55.31  ? 323 ARG B O   1 
ATOM   6214  C CB  . ARG B 1 323 ? 135.420 151.499 168.440 1.00 55.31  ? 323 ARG B CB  1 
ATOM   6215  C CG  . ARG B 1 323 ? 135.800 150.625 169.618 1.00 55.31  ? 323 ARG B CG  1 
ATOM   6216  C CD  . ARG B 1 323 ? 134.574 150.073 170.330 1.00 55.31  ? 323 ARG B CD  1 
ATOM   6217  N NE  . ARG B 1 323 ? 134.186 148.761 169.826 1.00 55.31  ? 323 ARG B NE  1 
ATOM   6218  C CZ  . ARG B 1 323 ? 133.066 148.518 169.159 1.00 55.31  ? 323 ARG B CZ  1 
ATOM   6219  N NH1 . ARG B 1 323 ? 132.191 149.476 168.906 1.00 55.31  ? 323 ARG B NH1 1 
ATOM   6220  N NH2 . ARG B 1 323 ? 132.816 147.280 168.741 1.00 55.31  ? 323 ARG B NH2 1 
ATOM   6221  N N   . ASN B 1 324 ? 136.002 154.699 168.367 1.00 58.25  ? 324 ASN B N   1 
ATOM   6222  C CA  . ASN B 1 324 ? 136.104 156.004 169.011 1.00 58.25  ? 324 ASN B CA  1 
ATOM   6223  C C   . ASN B 1 324 ? 134.905 156.190 169.935 1.00 58.25  ? 324 ASN B C   1 
ATOM   6224  O O   . ASN B 1 324 ? 133.761 156.248 169.474 1.00 58.25  ? 324 ASN B O   1 
ATOM   6225  C CB  . ASN B 1 324 ? 136.175 157.113 167.964 1.00 58.25  ? 324 ASN B CB  1 
ATOM   6226  C CG  . ASN B 1 324 ? 136.769 158.394 168.509 1.00 58.25  ? 324 ASN B CG  1 
ATOM   6227  O OD1 . ASN B 1 324 ? 137.817 158.381 169.150 1.00 58.25  ? 324 ASN B OD1 1 
ATOM   6228  N ND2 . ASN B 1 324 ? 136.103 159.511 168.249 1.00 58.25  ? 324 ASN B ND2 1 
ATOM   6229  N N   . VAL B 1 325 ? 135.169 156.286 171.229 1.00 66.15  ? 325 VAL B N   1 
ATOM   6230  C CA  . VAL B 1 325 ? 134.137 156.417 172.256 1.00 66.15  ? 325 VAL B CA  1 
ATOM   6231  C C   . VAL B 1 325 ? 134.328 157.758 172.952 1.00 66.15  ? 325 VAL B C   1 
ATOM   6232  O O   . VAL B 1 325 ? 135.435 158.047 173.418 1.00 66.15  ? 325 VAL B O   1 
ATOM   6233  C CB  . VAL B 1 325 ? 134.194 155.263 173.276 1.00 66.15  ? 325 VAL B CB  1 
ATOM   6234  C CG1 . VAL B 1 325 ? 133.018 155.339 174.235 1.00 66.15  ? 325 VAL B CG1 1 
ATOM   6235  C CG2 . VAL B 1 325 ? 134.215 153.924 172.559 1.00 66.15  ? 325 VAL B CG2 1 
ATOM   6236  N N   . PRO B 1 326 ? 133.297 158.595 173.040 1.00 71.04  ? 326 PRO B N   1 
ATOM   6237  C CA  . PRO B 1 326 ? 133.461 159.900 173.690 1.00 71.04  ? 326 PRO B CA  1 
ATOM   6238  C C   . PRO B 1 326 ? 133.629 159.778 175.197 1.00 71.04  ? 326 PRO B C   1 
ATOM   6239  O O   . PRO B 1 326 ? 133.174 158.820 175.826 1.00 71.04  ? 326 PRO B O   1 
ATOM   6240  C CB  . PRO B 1 326 ? 132.167 160.641 173.335 1.00 71.04  ? 326 PRO B CB  1 
ATOM   6241  C CG  . PRO B 1 326 ? 131.172 159.573 173.061 1.00 71.04  ? 326 PRO B CG  1 
ATOM   6242  C CD  . PRO B 1 326 ? 131.912 158.349 172.603 1.00 71.04  ? 326 PRO B CD  1 
ATOM   6243  N N   . GLU B 1 327 ? 134.297 160.774 175.773 1.00 76.71  ? 327 GLU B N   1 
ATOM   6244  C CA  . GLU B 1 327 ? 134.478 160.841 177.216 1.00 76.71  ? 327 GLU B CA  1 
ATOM   6245  C C   . GLU B 1 327 ? 133.298 161.558 177.860 1.00 76.71  ? 327 GLU B C   1 
ATOM   6246  O O   . GLU B 1 327 ? 133.025 162.722 177.550 1.00 76.71  ? 327 GLU B O   1 
ATOM   6247  C CB  . GLU B 1 327 ? 135.779 161.563 177.559 1.00 76.71  ? 327 GLU B CB  1 
ATOM   6248  C CG  . GLU B 1 327 ? 136.087 161.607 179.048 1.00 76.71  ? 327 GLU B CG  1 
ATOM   6249  C CD  . GLU B 1 327 ? 137.568 161.500 179.343 1.00 76.71  ? 327 GLU B CD  1 
ATOM   6250  O OE1 . GLU B 1 327 ? 138.375 161.635 178.400 1.00 76.71  ? 327 GLU B OE1 1 
ATOM   6251  O OE2 . GLU B 1 327 ? 137.927 161.282 180.518 1.00 76.71  ? 327 GLU B OE2 1 
ATOM   6252  N N   . LYS B 1 328 ? 132.605 160.867 178.758 1.00 78.73  ? 328 LYS B N   1 
ATOM   6253  C CA  . LYS B 1 328 ? 131.467 161.457 179.455 1.00 78.73  ? 328 LYS B CA  1 
ATOM   6254  C C   . LYS B 1 328 ? 131.928 162.463 180.506 1.00 78.73  ? 328 LYS B C   1 
ATOM   6255  O O   . LYS B 1 328 ? 133.025 162.350 181.050 1.00 78.73  ? 328 LYS B O   1 
ATOM   6256  C CB  . LYS B 1 328 ? 130.614 160.369 180.109 1.00 78.73  ? 328 LYS B CB  1 
ATOM   6257  C CG  . LYS B 1 328 ? 131.380 159.475 181.064 1.00 78.73  ? 328 LYS B CG  1 
ATOM   6258  C CD  . LYS B 1 328 ? 130.797 158.073 181.101 1.00 78.73  ? 328 LYS B CD  1 
ATOM   6259  C CE  . LYS B 1 328 ? 129.295 158.103 181.339 1.00 78.73  ? 328 LYS B CE  1 
ATOM   6260  N NZ  . LYS B 1 328 ? 128.612 156.915 180.757 1.00 78.73  ? 328 LYS B NZ  1 
ATOM   6261  N N   . ALA B 1 336 ? 136.244 161.358 190.546 1.00 86.72  ? 336 ALA B N   1 
ATOM   6262  C CA  . ALA B 1 336 ? 135.794 160.003 190.255 1.00 86.72  ? 336 ALA B CA  1 
ATOM   6263  C C   . ALA B 1 336 ? 136.241 159.565 188.864 1.00 86.72  ? 336 ALA B C   1 
ATOM   6264  O O   . ALA B 1 336 ? 135.546 159.800 187.876 1.00 86.72  ? 336 ALA B O   1 
ATOM   6265  C CB  . ALA B 1 336 ? 134.277 159.907 190.383 1.00 86.72  ? 336 ALA B CB  1 
ATOM   6266  N N   . ILE B 1 337 ? 137.409 158.927 188.795 1.00 84.86  ? 337 ILE B N   1 
ATOM   6267  C CA  . ILE B 1 337 ? 137.930 158.449 187.522 1.00 84.86  ? 337 ILE B CA  1 
ATOM   6268  C C   . ILE B 1 337 ? 137.194 157.180 187.103 1.00 84.86  ? 337 ILE B C   1 
ATOM   6269  O O   . ILE B 1 337 ? 136.627 156.453 187.923 1.00 84.86  ? 337 ILE B O   1 
ATOM   6270  C CB  . ILE B 1 337 ? 139.450 158.220 187.600 1.00 84.86  ? 337 ILE B CB  1 
ATOM   6271  C CG1 . ILE B 1 337 ? 139.789 157.203 188.691 1.00 84.86  ? 337 ILE B CG1 1 
ATOM   6272  C CG2 . ILE B 1 337 ? 140.171 159.529 187.858 1.00 84.86  ? 337 ILE B CG2 1 
ATOM   6273  C CD1 . ILE B 1 337 ? 141.257 156.850 188.751 1.00 84.86  ? 337 ILE B CD1 1 
ATOM   6274  N N   . ALA B 1 338 ? 137.203 156.915 185.798 1.00 81.01  ? 338 ALA B N   1 
ATOM   6275  C CA  . ALA B 1 338 ? 136.459 155.809 185.215 1.00 81.01  ? 338 ALA B CA  1 
ATOM   6276  C C   . ALA B 1 338 ? 137.383 154.948 184.365 1.00 81.01  ? 338 ALA B C   1 
ATOM   6277  O O   . ALA B 1 338 ? 138.523 155.317 184.068 1.00 81.01  ? 338 ALA B O   1 
ATOM   6278  C CB  . ALA B 1 338 ? 135.280 156.313 184.372 1.00 81.01  ? 338 ALA B CB  1 
ATOM   6279  N N   . GLY B 1 339 ? 136.876 153.788 183.974 1.00 77.72  ? 339 GLY B N   1 
ATOM   6280  C CA  . GLY B 1 339 ? 137.602 152.830 183.169 1.00 77.72  ? 339 GLY B CA  1 
ATOM   6281  C C   . GLY B 1 339 ? 137.253 152.917 181.699 1.00 77.72  ? 339 GLY B C   1 
ATOM   6282  O O   . GLY B 1 339 ? 136.844 153.969 181.193 1.00 77.72  ? 339 GLY B O   1 
ATOM   6283  N N   . PHE B 1 340 ? 137.410 151.794 181.002 1.00 74.65  ? 340 PHE B N   1 
ATOM   6284  C CA  . PHE B 1 340 ? 137.185 151.725 179.564 1.00 74.65  ? 340 PHE B CA  1 
ATOM   6285  C C   . PHE B 1 340 ? 135.751 151.370 179.193 1.00 74.65  ? 340 PHE B C   1 
ATOM   6286  O O   . PHE B 1 340 ? 135.428 151.339 178.002 1.00 74.65  ? 340 PHE B O   1 
ATOM   6287  C CB  . PHE B 1 340 ? 138.137 150.705 178.929 1.00 74.65  ? 340 PHE B CB  1 
ATOM   6288  C CG  . PHE B 1 340 ? 137.881 149.284 179.350 1.00 74.65  ? 340 PHE B CG  1 
ATOM   6289  C CD1 . PHE B 1 340 ? 138.463 148.772 180.496 1.00 74.65  ? 340 PHE B CD1 1 
ATOM   6290  C CD2 . PHE B 1 340 ? 137.067 148.457 178.593 1.00 74.65  ? 340 PHE B CD2 1 
ATOM   6291  C CE1 . PHE B 1 340 ? 138.234 147.469 180.884 1.00 74.65  ? 340 PHE B CE1 1 
ATOM   6292  C CE2 . PHE B 1 340 ? 136.832 147.152 178.977 1.00 74.65  ? 340 PHE B CE2 1 
ATOM   6293  C CZ  . PHE B 1 340 ? 137.416 146.657 180.123 1.00 74.65  ? 340 PHE B CZ  1 
ATOM   6294  N N   . ILE B 1 341 ? 134.886 151.100 180.168 1.00 76.89  ? 341 ILE B N   1 
ATOM   6295  C CA  . ILE B 1 341 ? 133.530 150.659 179.864 1.00 76.89  ? 341 ILE B CA  1 
ATOM   6296  C C   . ILE B 1 341 ? 132.708 151.842 179.367 1.00 76.89  ? 341 ILE B C   1 
ATOM   6297  O O   . ILE B 1 341 ? 132.293 152.701 180.153 1.00 76.89  ? 341 ILE B O   1 
ATOM   6298  C CB  . ILE B 1 341 ? 132.874 149.991 181.086 1.00 76.89  ? 341 ILE B CB  1 
ATOM   6299  C CG1 . ILE B 1 341 ? 133.771 148.868 181.619 1.00 76.89  ? 341 ILE B CG1 1 
ATOM   6300  C CG2 . ILE B 1 341 ? 131.489 149.471 180.731 1.00 76.89  ? 341 ILE B CG2 1 
ATOM   6301  C CD1 . ILE B 1 341 ? 133.459 147.496 181.055 1.00 76.89  ? 341 ILE B CD1 1 
ATOM   6302  N N   . GLU B 1 342 ? 132.481 151.887 178.052 1.00 77.73  ? 342 GLU B N   1 
ATOM   6303  C CA  . GLU B 1 342 ? 131.692 152.936 177.400 1.00 77.73  ? 342 GLU B CA  1 
ATOM   6304  C C   . GLU B 1 342 ? 132.233 154.327 177.723 1.00 77.73  ? 342 GLU B C   1 
ATOM   6305  O O   . GLU B 1 342 ? 131.479 155.281 177.918 1.00 77.73  ? 342 GLU B O   1 
ATOM   6306  C CB  . GLU B 1 342 ? 130.212 152.824 177.775 1.00 77.73  ? 342 GLU B CB  1 
ATOM   6307  C CG  . GLU B 1 342 ? 129.673 151.404 177.743 1.00 77.73  ? 342 GLU B CG  1 
ATOM   6308  C CD  . GLU B 1 342 ? 128.742 151.149 176.573 1.00 77.73  ? 342 GLU B CD  1 
ATOM   6309  O OE1 . GLU B 1 342 ? 128.370 152.120 175.880 1.00 77.73  ? 342 GLU B OE1 1 
ATOM   6310  O OE2 . GLU B 1 342 ? 128.381 149.975 176.347 1.00 77.73  ? 342 GLU B OE2 1 
ATOM   6311  N N   . ASN B 1 343 ? 133.559 154.446 177.774 1.00 75.17  ? 343 ASN B N   1 
ATOM   6312  C CA  . ASN B 1 343 ? 134.190 155.717 178.102 1.00 75.17  ? 343 ASN B CA  1 
ATOM   6313  C C   . ASN B 1 343 ? 135.613 155.719 177.565 1.00 75.17  ? 343 ASN B C   1 
ATOM   6314  O O   . ASN B 1 343 ? 136.383 154.797 177.845 1.00 75.17  ? 343 ASN B O   1 
ATOM   6315  C CB  . ASN B 1 343 ? 134.184 155.959 179.617 1.00 75.17  ? 343 ASN B CB  1 
ATOM   6316  C CG  . ASN B 1 343 ? 135.065 157.123 180.028 1.00 75.17  ? 343 ASN B CG  1 
ATOM   6317  O OD1 . ASN B 1 343 ? 134.805 158.270 179.667 1.00 75.17  ? 343 ASN B OD1 1 
ATOM   6318  N ND2 . ASN B 1 343 ? 136.114 156.834 180.789 1.00 75.17  ? 343 ASN B ND2 1 
ATOM   6319  N N   . GLY B 1 344 ? 135.955 156.752 176.800 1.00 73.61  ? 344 GLY B N   1 
ATOM   6320  C CA  . GLY B 1 344 ? 137.302 156.906 176.287 1.00 73.61  ? 344 GLY B CA  1 
ATOM   6321  C C   . GLY B 1 344 ? 138.049 158.023 176.982 1.00 73.61  ? 344 GLY B C   1 
ATOM   6322  O O   . GLY B 1 344 ? 137.434 158.860 177.648 1.00 73.61  ? 344 GLY B O   1 
ATOM   6323  N N   . TRP B 1 345 ? 139.370 158.054 176.845 1.00 74.04  ? 345 TRP B N   1 
ATOM   6324  C CA  . TRP B 1 345 ? 140.208 159.044 177.517 1.00 74.04  ? 345 TRP B CA  1 
ATOM   6325  C C   . TRP B 1 345 ? 140.734 160.026 176.476 1.00 74.04  ? 345 TRP B C   1 
ATOM   6326  O O   . TRP B 1 345 ? 141.729 159.753 175.798 1.00 74.04  ? 345 TRP B O   1 
ATOM   6327  C CB  . TRP B 1 345 ? 141.350 158.372 178.272 1.00 74.04  ? 345 TRP B CB  1 
ATOM   6328  C CG  . TRP B 1 345 ? 140.912 157.646 179.503 1.00 74.04  ? 345 TRP B CG  1 
ATOM   6329  C CD1 . TRP B 1 345 ? 139.680 157.691 180.087 1.00 74.04  ? 345 TRP B CD1 1 
ATOM   6330  C CD2 . TRP B 1 345 ? 141.707 156.773 180.312 1.00 74.04  ? 345 TRP B CD2 1 
ATOM   6331  N NE1 . TRP B 1 345 ? 139.657 156.894 181.205 1.00 74.04  ? 345 TRP B NE1 1 
ATOM   6332  C CE2 . TRP B 1 345 ? 140.891 156.321 181.365 1.00 74.04  ? 345 TRP B CE2 1 
ATOM   6333  C CE3 . TRP B 1 345 ? 143.030 156.328 180.245 1.00 74.04  ? 345 TRP B CE3 1 
ATOM   6334  C CZ2 . TRP B 1 345 ? 141.353 155.445 182.343 1.00 74.04  ? 345 TRP B CZ2 1 
ATOM   6335  C CZ3 . TRP B 1 345 ? 143.487 155.460 181.217 1.00 74.04  ? 345 TRP B CZ3 1 
ATOM   6336  C CH2 . TRP B 1 345 ? 142.651 155.028 182.252 1.00 74.04  ? 345 TRP B CH2 1 
ATOM   6337  N N   . GLU B 1 346 ? 140.061 161.172 176.355 1.00 76.64  ? 346 GLU B N   1 
ATOM   6338  C CA  . GLU B 1 346 ? 140.534 162.221 175.460 1.00 76.64  ? 346 GLU B CA  1 
ATOM   6339  C C   . GLU B 1 346 ? 141.834 162.850 175.939 1.00 76.64  ? 346 GLU B C   1 
ATOM   6340  O O   . GLU B 1 346 ? 142.539 163.470 175.136 1.00 76.64  ? 346 GLU B O   1 
ATOM   6341  C CB  . GLU B 1 346 ? 139.467 163.306 175.303 1.00 76.64  ? 346 GLU B CB  1 
ATOM   6342  C CG  . GLU B 1 346 ? 138.564 163.120 174.098 1.00 76.64  ? 346 GLU B CG  1 
ATOM   6343  C CD  . GLU B 1 346 ? 137.899 164.411 173.663 1.00 76.64  ? 346 GLU B CD  1 
ATOM   6344  O OE1 . GLU B 1 346 ? 138.236 165.473 174.228 1.00 76.64  ? 346 GLU B OE1 1 
ATOM   6345  O OE2 . GLU B 1 346 ? 137.038 164.363 172.760 1.00 76.64  ? 346 GLU B OE2 1 
ATOM   6346  N N   . GLY B 1 347 ? 142.170 162.701 177.217 1.00 78.65  ? 347 GLY B N   1 
ATOM   6347  C CA  . GLY B 1 347 ? 143.355 163.329 177.765 1.00 78.65  ? 347 GLY B CA  1 
ATOM   6348  C C   . GLY B 1 347 ? 144.603 162.473 177.689 1.00 78.65  ? 347 GLY B C   1 
ATOM   6349  O O   . GLY B 1 347 ? 145.588 162.746 178.380 1.00 78.65  ? 347 GLY B O   1 
ATOM   6350  N N   . MET B 1 348 ? 144.578 161.434 176.860 1.00 78.23  ? 348 MET B N   1 
ATOM   6351  C CA  . MET B 1 348 ? 145.711 160.531 176.702 1.00 78.23  ? 348 MET B CA  1 
ATOM   6352  C C   . MET B 1 348 ? 146.302 160.713 175.312 1.00 78.23  ? 348 MET B C   1 
ATOM   6353  O O   . MET B 1 348 ? 145.619 160.488 174.308 1.00 78.23  ? 348 MET B O   1 
ATOM   6354  C CB  . MET B 1 348 ? 145.293 159.078 176.923 1.00 78.23  ? 348 MET B CB  1 
ATOM   6355  C CG  . MET B 1 348 ? 146.441 158.091 176.827 1.00 78.23  ? 348 MET B CG  1 
ATOM   6356  S SD  . MET B 1 348 ? 146.243 156.674 177.921 1.00 78.23  ? 348 MET B SD  1 
ATOM   6357  C CE  . MET B 1 348 ? 145.350 155.550 176.852 1.00 78.23  ? 348 MET B CE  1 
ATOM   6358  N N   . ILE B 1 349 ? 147.573 161.116 175.259 1.00 79.66  ? 349 ILE B N   1 
ATOM   6359  C CA  . ILE B 1 349 ? 148.287 161.290 174.001 1.00 79.66  ? 349 ILE B CA  1 
ATOM   6360  C C   . ILE B 1 349 ? 149.615 160.550 173.973 1.00 79.66  ? 349 ILE B C   1 
ATOM   6361  O O   . ILE B 1 349 ? 150.424 160.790 173.076 1.00 79.66  ? 349 ILE B O   1 
ATOM   6362  C CB  . ILE B 1 349 ? 148.502 162.785 173.680 1.00 79.66  ? 349 ILE B CB  1 
ATOM   6363  C CG1 . ILE B 1 349 ? 149.079 163.531 174.889 1.00 79.66  ? 349 ILE B CG1 1 
ATOM   6364  C CG2 . ILE B 1 349 ? 147.198 163.425 173.228 1.00 79.66  ? 349 ILE B CG2 1 
ATOM   6365  C CD1 . ILE B 1 349 ? 150.593 163.546 174.959 1.00 79.66  ? 349 ILE B CD1 1 
ATOM   6366  N N   . ASP B 1 350 ? 149.868 159.657 174.928 1.00 78.45  ? 350 ASP B N   1 
ATOM   6367  C CA  . ASP B 1 350 ? 151.141 158.960 175.031 1.00 78.45  ? 350 ASP B CA  1 
ATOM   6368  C C   . ASP B 1 350 ? 151.078 157.515 174.557 1.00 78.45  ? 350 ASP B C   1 
ATOM   6369  O O   . ASP B 1 350 ? 152.118 156.849 174.514 1.00 78.45  ? 350 ASP B O   1 
ATOM   6370  C CB  . ASP B 1 350 ? 151.638 158.997 176.481 1.00 78.45  ? 350 ASP B CB  1 
ATOM   6371  C CG  . ASP B 1 350 ? 153.140 158.883 176.584 1.00 78.45  ? 350 ASP B CG  1 
ATOM   6372  O OD1 . ASP B 1 350 ? 153.836 159.378 175.673 1.00 78.45  ? 350 ASP B OD1 1 
ATOM   6373  O OD2 . ASP B 1 350 ? 153.626 158.297 177.573 1.00 78.45  ? 350 ASP B OD2 1 
ATOM   6374  N N   . GLY B 1 351 ? 149.900 157.019 174.201 1.00 72.82  ? 351 GLY B N   1 
ATOM   6375  C CA  . GLY B 1 351 ? 149.771 155.638 173.782 1.00 72.82  ? 351 GLY B CA  1 
ATOM   6376  C C   . GLY B 1 351 ? 148.329 155.319 173.459 1.00 72.82  ? 351 GLY B C   1 
ATOM   6377  O O   . GLY B 1 351 ? 147.475 156.206 173.401 1.00 72.82  ? 351 GLY B O   1 
ATOM   6378  N N   . TRP B 1 352 ? 148.068 154.032 173.245 1.00 65.68  ? 352 TRP B N   1 
ATOM   6379  C CA  . TRP B 1 352 ? 146.725 153.559 172.931 1.00 65.68  ? 352 TRP B CA  1 
ATOM   6380  C C   . TRP B 1 352 ? 145.995 153.004 174.145 1.00 65.68  ? 352 TRP B C   1 
ATOM   6381  O O   . TRP B 1 352 ? 144.800 153.257 174.309 1.00 65.68  ? 352 TRP B O   1 
ATOM   6382  C CB  . TRP B 1 352 ? 146.782 152.491 171.833 1.00 65.68  ? 352 TRP B CB  1 
ATOM   6383  C CG  . TRP B 1 352 ? 147.050 153.048 170.466 1.00 65.68  ? 352 TRP B CG  1 
ATOM   6384  C CD1 . TRP B 1 352 ? 147.611 154.255 170.168 1.00 65.68  ? 352 TRP B CD1 1 
ATOM   6385  C CD2 . TRP B 1 352 ? 146.766 152.417 169.212 1.00 65.68  ? 352 TRP B CD2 1 
ATOM   6386  N NE1 . TRP B 1 352 ? 147.695 154.415 168.807 1.00 65.68  ? 352 TRP B NE1 1 
ATOM   6387  C CE2 . TRP B 1 352 ? 147.183 153.301 168.197 1.00 65.68  ? 352 TRP B CE2 1 
ATOM   6388  C CE3 . TRP B 1 352 ? 146.200 151.193 168.850 1.00 65.68  ? 352 TRP B CE3 1 
ATOM   6389  C CZ2 . TRP B 1 352 ? 147.052 152.998 166.845 1.00 65.68  ? 352 TRP B CZ2 1 
ATOM   6390  C CZ3 . TRP B 1 352 ? 146.071 150.894 167.508 1.00 65.68  ? 352 TRP B CZ3 1 
ATOM   6391  C CH2 . TRP B 1 352 ? 146.495 151.793 166.521 1.00 65.68  ? 352 TRP B CH2 1 
ATOM   6392  N N   . TYR B 1 353 ? 146.688 152.255 174.997 1.00 66.44  ? 353 TYR B N   1 
ATOM   6393  C CA  . TYR B 1 353 ? 146.131 151.714 176.227 1.00 66.44  ? 353 TYR B CA  1 
ATOM   6394  C C   . TYR B 1 353 ? 146.944 152.227 177.407 1.00 66.44  ? 353 TYR B C   1 
ATOM   6395  O O   . TYR B 1 353 ? 148.149 152.464 177.286 1.00 66.44  ? 353 TYR B O   1 
ATOM   6396  C CB  . TYR B 1 353 ? 146.139 150.183 176.214 1.00 66.44  ? 353 TYR B CB  1 
ATOM   6397  C CG  . TYR B 1 353 ? 145.501 149.574 174.989 1.00 66.44  ? 353 TYR B CG  1 
ATOM   6398  C CD1 . TYR B 1 353 ? 144.145 149.285 174.961 1.00 66.44  ? 353 TYR B CD1 1 
ATOM   6399  C CD2 . TYR B 1 353 ? 146.255 149.288 173.859 1.00 66.44  ? 353 TYR B CD2 1 
ATOM   6400  C CE1 . TYR B 1 353 ? 143.559 148.728 173.846 1.00 66.44  ? 353 TYR B CE1 1 
ATOM   6401  C CE2 . TYR B 1 353 ? 145.676 148.732 172.738 1.00 66.44  ? 353 TYR B CE2 1 
ATOM   6402  C CZ  . TYR B 1 353 ? 144.328 148.455 172.737 1.00 66.44  ? 353 TYR B CZ  1 
ATOM   6403  O OH  . TYR B 1 353 ? 143.745 147.900 171.624 1.00 66.44  ? 353 TYR B OH  1 
ATOM   6404  N N   . GLY B 1 354 ? 146.289 152.398 178.550 1.00 72.32  ? 354 GLY B N   1 
ATOM   6405  C CA  . GLY B 1 354 ? 147.005 152.961 179.681 1.00 72.32  ? 354 GLY B CA  1 
ATOM   6406  C C   . GLY B 1 354 ? 146.292 152.762 181.000 1.00 72.32  ? 354 GLY B C   1 
ATOM   6407  O O   . GLY B 1 354 ? 145.146 152.305 181.063 1.00 72.32  ? 354 GLY B O   1 
ATOM   6408  N N   . PHE B 1 355 ? 147.011 153.129 182.058 1.00 77.35  ? 355 PHE B N   1 
ATOM   6409  C CA  . PHE B 1 355 ? 146.557 153.056 183.436 1.00 77.35  ? 355 PHE B CA  1 
ATOM   6410  C C   . PHE B 1 355 ? 146.361 154.458 183.998 1.00 77.35  ? 355 PHE B C   1 
ATOM   6411  O O   . PHE B 1 355 ? 147.040 155.409 183.600 1.00 77.35  ? 355 PHE B O   1 
ATOM   6412  C CB  . PHE B 1 355 ? 147.566 152.323 184.330 1.00 77.35  ? 355 PHE B CB  1 
ATOM   6413  C CG  . PHE B 1 355 ? 147.853 150.909 183.920 1.00 77.35  ? 355 PHE B CG  1 
ATOM   6414  C CD1 . PHE B 1 355 ? 148.814 150.631 182.962 1.00 77.35  ? 355 PHE B CD1 1 
ATOM   6415  C CD2 . PHE B 1 355 ? 147.189 149.853 184.520 1.00 77.35  ? 355 PHE B CD2 1 
ATOM   6416  C CE1 . PHE B 1 355 ? 149.091 149.329 182.597 1.00 77.35  ? 355 PHE B CE1 1 
ATOM   6417  C CE2 . PHE B 1 355 ? 147.461 148.550 184.158 1.00 77.35  ? 355 PHE B CE2 1 
ATOM   6418  C CZ  . PHE B 1 355 ? 148.413 148.287 183.195 1.00 77.35  ? 355 PHE B CZ  1 
ATOM   6419  N N   . ARG B 1 356 ? 145.435 154.568 184.942 1.00 79.83  ? 356 ARG B N   1 
ATOM   6420  C CA  . ARG B 1 356 ? 145.281 155.752 185.771 1.00 79.83  ? 356 ARG B CA  1 
ATOM   6421  C C   . ARG B 1 356 ? 145.160 155.302 187.217 1.00 79.83  ? 356 ARG B C   1 
ATOM   6422  O O   . ARG B 1 356 ? 144.621 154.228 187.493 1.00 79.83  ? 356 ARG B O   1 
ATOM   6423  C CB  . ARG B 1 356 ? 144.053 156.569 185.365 1.00 79.83  ? 356 ARG B CB  1 
ATOM   6424  C CG  . ARG B 1 356 ? 144.310 157.554 184.242 1.00 79.83  ? 356 ARG B CG  1 
ATOM   6425  C CD  . ARG B 1 356 ? 143.068 158.372 183.944 1.00 79.83  ? 356 ARG B CD  1 
ATOM   6426  N NE  . ARG B 1 356 ? 143.252 159.246 182.792 1.00 79.83  ? 356 ARG B NE  1 
ATOM   6427  C CZ  . ARG B 1 356 ? 142.284 159.958 182.232 1.00 79.83  ? 356 ARG B CZ  1 
ATOM   6428  N NH1 . ARG B 1 356 ? 141.045 159.924 182.693 1.00 79.83  ? 356 ARG B NH1 1 
ATOM   6429  N NH2 . ARG B 1 356 ? 142.567 160.721 181.182 1.00 79.83  ? 356 ARG B NH2 1 
ATOM   6430  N N   . HIS B 1 357 ? 145.674 156.104 188.141 1.00 87.15  ? 357 HIS B N   1 
ATOM   6431  C CA  . HIS B 1 357 ? 145.593 155.762 189.553 1.00 87.15  ? 357 HIS B CA  1 
ATOM   6432  C C   . HIS B 1 357 ? 145.177 156.974 190.370 1.00 87.15  ? 357 HIS B C   1 
ATOM   6433  O O   . HIS B 1 357 ? 145.601 158.100 190.098 1.00 87.15  ? 357 HIS B O   1 
ATOM   6434  C CB  . HIS B 1 357 ? 146.921 155.189 190.078 1.00 87.15  ? 357 HIS B CB  1 
ATOM   6435  C CG  . HIS B 1 357 ? 148.064 156.154 190.045 1.00 87.15  ? 357 HIS B CG  1 
ATOM   6436  N ND1 . HIS B 1 357 ? 149.020 156.140 189.053 1.00 87.15  ? 357 HIS B ND1 1 
ATOM   6437  C CD2 . HIS B 1 357 ? 148.420 157.145 190.897 1.00 87.15  ? 357 HIS B CD2 1 
ATOM   6438  C CE1 . HIS B 1 357 ? 149.908 157.089 189.287 1.00 87.15  ? 357 HIS B CE1 1 
ATOM   6439  N NE2 . HIS B 1 357 ? 149.567 157.714 190.400 1.00 87.15  ? 357 HIS B NE2 1 
ATOM   6440  N N   . GLN B 1 358 ? 144.329 156.723 191.362 1.00 90.86  ? 358 GLN B N   1 
ATOM   6441  C CA  . GLN B 1 358 ? 143.856 157.727 192.302 1.00 90.86  ? 358 GLN B CA  1 
ATOM   6442  C C   . GLN B 1 358 ? 144.319 157.326 193.693 1.00 90.86  ? 358 GLN B C   1 
ATOM   6443  O O   . GLN B 1 358 ? 144.081 156.192 194.128 1.00 90.86  ? 358 GLN B O   1 
ATOM   6444  C CB  . GLN B 1 358 ? 142.332 157.849 192.252 1.00 90.86  ? 358 GLN B CB  1 
ATOM   6445  C CG  . GLN B 1 358 ? 141.787 159.158 192.790 1.00 90.86  ? 358 GLN B CG  1 
ATOM   6446  C CD  . GLN B 1 358 ? 140.278 159.139 192.920 1.00 90.86  ? 358 GLN B CD  1 
ATOM   6447  O OE1 . GLN B 1 358 ? 139.713 158.284 193.602 1.00 90.86  ? 358 GLN B OE1 1 
ATOM   6448  N NE2 . GLN B 1 358 ? 139.616 160.079 192.257 1.00 90.86  ? 358 GLN B NE2 1 
ATOM   6449  N N   . ASN B 1 359 ? 144.964 158.256 194.389 1.00 96.47  ? 359 ASN B N   1 
ATOM   6450  C CA  . ASN B 1 359 ? 145.744 157.922 195.571 1.00 96.47  ? 359 ASN B CA  1 
ATOM   6451  C C   . ASN B 1 359 ? 145.758 159.121 196.511 1.00 96.47  ? 359 ASN B C   1 
ATOM   6452  O O   . ASN B 1 359 ? 145.207 160.183 196.206 1.00 96.47  ? 359 ASN B O   1 
ATOM   6453  C CB  . ASN B 1 359 ? 147.162 157.511 195.170 1.00 96.47  ? 359 ASN B CB  1 
ATOM   6454  C CG  . ASN B 1 359 ? 147.785 156.547 196.141 1.00 96.47  ? 359 ASN B CG  1 
ATOM   6455  O OD1 . ASN B 1 359 ? 147.105 155.967 196.986 1.00 96.47  ? 359 ASN B OD1 1 
ATOM   6456  N ND2 . ASN B 1 359 ? 149.093 156.375 196.034 1.00 96.47  ? 359 ASN B ND2 1 
ATOM   6457  N N   . SER B 1 360 ? 146.396 158.936 197.670 1.00 98.09  ? 360 SER B N   1 
ATOM   6458  C CA  . SER B 1 360 ? 146.551 160.036 198.617 1.00 98.09  ? 360 SER B CA  1 
ATOM   6459  C C   . SER B 1 360 ? 147.427 161.141 198.041 1.00 98.09  ? 360 SER B C   1 
ATOM   6460  O O   . SER B 1 360 ? 147.141 162.330 198.227 1.00 98.09  ? 360 SER B O   1 
ATOM   6461  C CB  . SER B 1 360 ? 147.134 159.516 199.931 1.00 98.09  ? 360 SER B CB  1 
ATOM   6462  O OG  . SER B 1 360 ? 148.460 159.052 199.751 1.00 98.09  ? 360 SER B OG  1 
ATOM   6463  N N   . GLU B 1 361 ? 148.505 160.769 197.345 1.00 98.78  ? 361 GLU B N   1 
ATOM   6464  C CA  . GLU B 1 361 ? 149.354 161.768 196.703 1.00 98.78  ? 361 GLU B CA  1 
ATOM   6465  C C   . GLU B 1 361 ? 148.587 162.536 195.635 1.00 98.78  ? 361 GLU B C   1 
ATOM   6466  O O   . GLU B 1 361 ? 148.750 163.753 195.495 1.00 98.78  ? 361 GLU B O   1 
ATOM   6467  C CB  . GLU B 1 361 ? 150.587 161.101 196.095 1.00 98.78  ? 361 GLU B CB  1 
ATOM   6468  C CG  . GLU B 1 361 ? 151.752 160.936 197.051 1.00 98.78  ? 361 GLU B CG  1 
ATOM   6469  C CD  . GLU B 1 361 ? 152.479 159.624 196.848 1.00 98.78  ? 361 GLU B CD  1 
ATOM   6470  O OE1 . GLU B 1 361 ? 151.803 158.611 196.574 1.00 98.78  ? 361 GLU B OE1 1 
ATOM   6471  O OE2 . GLU B 1 361 ? 153.724 159.606 196.950 1.00 98.78  ? 361 GLU B OE2 1 
ATOM   6472  N N   . GLY B 1 362 ? 147.756 161.846 194.877 1.00 95.79  ? 362 GLY B N   1 
ATOM   6473  C CA  . GLY B 1 362 ? 146.957 162.487 193.852 1.00 95.79  ? 362 GLY B CA  1 
ATOM   6474  C C   . GLY B 1 362 ? 146.786 161.564 192.664 1.00 95.79  ? 362 GLY B C   1 
ATOM   6475  O O   . GLY B 1 362 ? 147.273 160.437 192.643 1.00 95.79  ? 362 GLY B O   1 
ATOM   6476  N N   . THR B 1 363 ? 146.071 162.075 191.668 1.00 91.50  ? 363 THR B N   1 
ATOM   6477  C CA  . THR B 1 363 ? 145.852 161.323 190.443 1.00 91.50  ? 363 THR B CA  1 
ATOM   6478  C C   . THR B 1 363 ? 147.134 161.245 189.619 1.00 91.50  ? 363 THR B C   1 
ATOM   6479  O O   . THR B 1 363 ? 147.968 162.153 189.632 1.00 91.50  ? 363 THR B O   1 
ATOM   6480  C CB  . THR B 1 363 ? 144.740 161.961 189.611 1.00 91.50  ? 363 THR B CB  1 
ATOM   6481  O OG1 . THR B 1 363 ? 145.181 163.232 189.118 1.00 91.50  ? 363 THR B OG1 1 
ATOM   6482  C CG2 . THR B 1 363 ? 143.489 162.154 190.452 1.00 91.50  ? 363 THR B CG2 1 
ATOM   6483  N N   . GLY B 1 364 ? 147.280 160.136 188.901 1.00 85.89  ? 364 GLY B N   1 
ATOM   6484  C CA  . GLY B 1 364 ? 148.408 159.945 188.008 1.00 85.89  ? 364 GLY B CA  1 
ATOM   6485  C C   . GLY B 1 364 ? 147.991 159.090 186.832 1.00 85.89  ? 364 GLY B C   1 
ATOM   6486  O O   . GLY B 1 364 ? 147.008 158.347 186.898 1.00 85.89  ? 364 GLY B O   1 
ATOM   6487  N N   . GLN B 1 365 ? 148.756 159.199 185.748 1.00 80.97  ? 365 GLN B N   1 
ATOM   6488  C CA  . GLN B 1 365 ? 148.419 158.529 184.501 1.00 80.97  ? 365 GLN B CA  1 
ATOM   6489  C C   . GLN B 1 365 ? 149.682 157.982 183.852 1.00 80.97  ? 365 GLN B C   1 
ATOM   6490  O O   . GLN B 1 365 ? 150.768 158.547 184.001 1.00 80.97  ? 365 GLN B O   1 
ATOM   6491  C CB  . GLN B 1 365 ? 147.696 159.486 183.541 1.00 80.97  ? 365 GLN B CB  1 
ATOM   6492  C CG  . GLN B 1 365 ? 147.151 158.841 182.280 1.00 80.97  ? 365 GLN B CG  1 
ATOM   6493  C CD  . GLN B 1 365 ? 146.204 159.752 181.523 1.00 80.97  ? 365 GLN B CD  1 
ATOM   6494  O OE1 . GLN B 1 365 ? 145.756 160.772 182.045 1.00 80.97  ? 365 GLN B OE1 1 
ATOM   6495  N NE2 . GLN B 1 365 ? 145.896 159.389 180.285 1.00 80.97  ? 365 GLN B NE2 1 
ATOM   6496  N N   . ALA B 1 366 ? 149.530 156.874 183.132 1.00 78.35  ? 366 ALA B N   1 
ATOM   6497  C CA  . ALA B 1 366 ? 150.638 156.275 182.402 1.00 78.35  ? 366 ALA B CA  1 
ATOM   6498  C C   . ALA B 1 366 ? 150.066 155.434 181.271 1.00 78.35  ? 366 ALA B C   1 
ATOM   6499  O O   . ALA B 1 366 ? 148.866 155.162 181.222 1.00 78.35  ? 366 ALA B O   1 
ATOM   6500  C CB  . ALA B 1 366 ? 151.530 155.432 183.318 1.00 78.35  ? 366 ALA B CB  1 
ATOM   6501  N N   . ALA B 1 367 ? 150.946 155.013 180.369 1.00 74.84  ? 367 ALA B N   1 
ATOM   6502  C CA  . ALA B 1 367 ? 150.556 154.249 179.196 1.00 74.84  ? 367 ALA B CA  1 
ATOM   6503  C C   . ALA B 1 367 ? 151.215 152.876 179.217 1.00 74.84  ? 367 ALA B C   1 
ATOM   6504  O O   . ALA B 1 367 ? 152.244 152.663 179.861 1.00 74.84  ? 367 ALA B O   1 
ATOM   6505  C CB  . ALA B 1 367 ? 150.926 154.987 177.904 1.00 74.84  ? 367 ALA B CB  1 
ATOM   6506  N N   . ASP B 1 368 ? 150.599 151.941 178.500 1.00 72.59  ? 368 ASP B N   1 
ATOM   6507  C CA  . ASP B 1 368 ? 151.098 150.578 178.378 1.00 72.59  ? 368 ASP B CA  1 
ATOM   6508  C C   . ASP B 1 368 ? 151.732 150.414 177.003 1.00 72.59  ? 368 ASP B C   1 
ATOM   6509  O O   . ASP B 1 368 ? 151.072 150.631 175.981 1.00 72.59  ? 368 ASP B O   1 
ATOM   6510  C CB  . ASP B 1 368 ? 149.969 149.568 178.582 1.00 72.59  ? 368 ASP B CB  1 
ATOM   6511  C CG  . ASP B 1 368 ? 150.478 148.185 178.936 1.00 72.59  ? 368 ASP B CG  1 
ATOM   6512  O OD1 . ASP B 1 368 ? 151.405 147.694 178.259 1.00 72.59  ? 368 ASP B OD1 1 
ATOM   6513  O OD2 . ASP B 1 368 ? 149.953 147.590 179.897 1.00 72.59  ? 368 ASP B OD2 1 
ATOM   6514  N N   . LEU B 1 369 ? 153.008 150.030 176.980 1.00 71.04  ? 369 LEU B N   1 
ATOM   6515  C CA  . LEU B 1 369 ? 153.737 149.966 175.718 1.00 71.04  ? 369 LEU B CA  1 
ATOM   6516  C C   . LEU B 1 369 ? 153.557 148.624 175.020 1.00 71.04  ? 369 LEU B C   1 
ATOM   6517  O O   . LEU B 1 369 ? 153.502 148.570 173.788 1.00 71.04  ? 369 LEU B O   1 
ATOM   6518  C CB  . LEU B 1 369 ? 155.221 150.246 175.957 1.00 71.04  ? 369 LEU B CB  1 
ATOM   6519  C CG  . LEU B 1 369 ? 155.551 151.465 176.822 1.00 71.04  ? 369 LEU B CG  1 
ATOM   6520  C CD1 . LEU B 1 369 ? 157.055 151.674 176.901 1.00 71.04  ? 369 LEU B CD1 1 
ATOM   6521  C CD2 . LEU B 1 369 ? 154.862 152.712 176.287 1.00 71.04  ? 369 LEU B CD2 1 
ATOM   6522  N N   . LYS B 1 370 ? 153.461 147.533 175.783 1.00 70.39  ? 370 LYS B N   1 
ATOM   6523  C CA  . LYS B 1 370 ? 153.413 146.205 175.177 1.00 70.39  ? 370 LYS B CA  1 
ATOM   6524  C C   . LYS B 1 370 ? 152.123 145.991 174.391 1.00 70.39  ? 370 LYS B C   1 
ATOM   6525  O O   . LYS B 1 370 ? 152.154 145.537 173.240 1.00 70.39  ? 370 LYS B O   1 
ATOM   6526  C CB  . LYS B 1 370 ? 153.571 145.135 176.257 1.00 70.39  ? 370 LYS B CB  1 
ATOM   6527  C CG  . LYS B 1 370 ? 154.905 145.183 176.981 1.00 70.39  ? 370 LYS B CG  1 
ATOM   6528  C CD  . LYS B 1 370 ? 154.996 144.099 178.042 1.00 70.39  ? 370 LYS B CD  1 
ATOM   6529  C CE  . LYS B 1 370 ? 156.375 144.062 178.678 1.00 70.39  ? 370 LYS B CE  1 
ATOM   6530  N NZ  . LYS B 1 370 ? 156.491 142.970 179.684 1.00 70.39  ? 370 LYS B NZ  1 
ATOM   6531  N N   . SER B 1 371 ? 150.976 146.306 174.997 1.00 69.01  ? 371 SER B N   1 
ATOM   6532  C CA  . SER B 1 371 ? 149.701 146.105 174.312 1.00 69.01  ? 371 SER B CA  1 
ATOM   6533  C C   . SER B 1 371 ? 149.556 147.050 173.125 1.00 69.01  ? 371 SER B C   1 
ATOM   6534  O O   . SER B 1 371 ? 149.046 146.656 172.067 1.00 69.01  ? 371 SER B O   1 
ATOM   6535  C CB  . SER B 1 371 ? 148.544 146.283 175.294 1.00 69.01  ? 371 SER B CB  1 
ATOM   6536  O OG  . SER B 1 371 ? 148.614 147.537 175.948 1.00 69.01  ? 371 SER B OG  1 
ATOM   6537  N N   . THR B 1 372 ? 150.002 148.298 173.281 1.00 67.11  ? 372 THR B N   1 
ATOM   6538  C CA  . THR B 1 372 ? 149.990 149.237 172.164 1.00 67.11  ? 372 THR B CA  1 
ATOM   6539  C C   . THR B 1 372 ? 150.840 148.719 171.011 1.00 67.11  ? 372 THR B C   1 
ATOM   6540  O O   . THR B 1 372 ? 150.423 148.762 169.847 1.00 67.11  ? 372 THR B O   1 
ATOM   6541  C CB  . THR B 1 372 ? 150.491 150.606 172.625 1.00 67.11  ? 372 THR B CB  1 
ATOM   6542  O OG1 . THR B 1 372 ? 149.660 151.093 173.686 1.00 67.11  ? 372 THR B OG1 1 
ATOM   6543  C CG2 . THR B 1 372 ? 150.464 151.596 171.476 1.00 67.11  ? 372 THR B CG2 1 
ATOM   6544  N N   . GLN B 1 373 ? 152.036 148.212 171.321 1.00 66.63  ? 373 GLN B N   1 
ATOM   6545  C CA  . GLN B 1 373 ? 152.912 147.693 170.279 1.00 66.63  ? 373 GLN B CA  1 
ATOM   6546  C C   . GLN B 1 373 ? 152.295 146.485 169.591 1.00 66.63  ? 373 GLN B C   1 
ATOM   6547  O O   . GLN B 1 373 ? 152.376 146.354 168.366 1.00 66.63  ? 373 GLN B O   1 
ATOM   6548  C CB  . GLN B 1 373 ? 154.277 147.337 170.867 1.00 66.63  ? 373 GLN B CB  1 
ATOM   6549  C CG  . GLN B 1 373 ? 155.319 146.962 169.828 1.00 66.63  ? 373 GLN B CG  1 
ATOM   6550  C CD  . GLN B 1 373 ? 155.581 148.076 168.833 1.00 66.63  ? 373 GLN B CD  1 
ATOM   6551  O OE1 . GLN B 1 373 ? 155.466 149.257 169.160 1.00 66.63  ? 373 GLN B OE1 1 
ATOM   6552  N NE2 . GLN B 1 373 ? 155.930 147.704 167.609 1.00 66.63  ? 373 GLN B NE2 1 
ATOM   6553  N N   . ALA B 1 374 ? 151.674 145.591 170.363 1.00 64.20  ? 374 ALA B N   1 
ATOM   6554  C CA  . ALA B 1 374 ? 151.027 144.427 169.766 1.00 64.20  ? 374 ALA B CA  1 
ATOM   6555  C C   . ALA B 1 374 ? 149.912 144.848 168.815 1.00 64.20  ? 374 ALA B C   1 
ATOM   6556  O O   . ALA B 1 374 ? 149.817 144.346 167.687 1.00 64.20  ? 374 ALA B O   1 
ATOM   6557  C CB  . ALA B 1 374 ? 150.485 143.510 170.862 1.00 64.20  ? 374 ALA B CB  1 
ATOM   6558  N N   . ALA B 1 375 ? 149.069 145.789 169.248 1.00 62.82  ? 375 ALA B N   1 
ATOM   6559  C CA  . ALA B 1 375 ? 147.970 146.241 168.400 1.00 62.82  ? 375 ALA B CA  1 
ATOM   6560  C C   . ALA B 1 375 ? 148.485 146.898 167.126 1.00 62.82  ? 375 ALA B C   1 
ATOM   6561  O O   . ALA B 1 375 ? 147.982 146.620 166.029 1.00 62.82  ? 375 ALA B O   1 
ATOM   6562  C CB  . ALA B 1 375 ? 147.069 147.202 169.173 1.00 62.82  ? 375 ALA B CB  1 
ATOM   6563  N N   . ILE B 1 376 ? 149.495 147.763 167.246 1.00 62.42  ? 376 ILE B N   1 
ATOM   6564  C CA  . ILE B 1 376 ? 150.013 148.456 166.070 1.00 62.42  ? 376 ILE B CA  1 
ATOM   6565  C C   . ILE B 1 376 ? 150.673 147.474 165.108 1.00 62.42  ? 376 ILE B C   1 
ATOM   6566  O O   . ILE B 1 376 ? 150.476 147.555 163.890 1.00 62.42  ? 376 ILE B O   1 
ATOM   6567  C CB  . ILE B 1 376 ? 150.975 149.582 166.487 1.00 62.42  ? 376 ILE B CB  1 
ATOM   6568  C CG1 . ILE B 1 376 ? 150.238 150.609 167.351 1.00 62.42  ? 376 ILE B CG1 1 
ATOM   6569  C CG2 . ILE B 1 376 ? 151.584 150.241 165.260 1.00 62.42  ? 376 ILE B CG2 1 
ATOM   6570  C CD1 . ILE B 1 376 ? 150.868 151.980 167.359 1.00 62.42  ? 376 ILE B CD1 1 
ATOM   6571  N N   . ASP B 1 377 ? 151.458 146.529 165.630 1.00 63.29  ? 377 ASP B N   1 
ATOM   6572  C CA  . ASP B 1 377 ? 152.098 145.545 164.768 1.00 63.29  ? 377 ASP B CA  1 
ATOM   6573  C C   . ASP B 1 377 ? 151.093 144.618 164.103 1.00 63.29  ? 377 ASP B C   1 
ATOM   6574  O O   . ASP B 1 377 ? 151.360 144.124 163.003 1.00 63.29  ? 377 ASP B O   1 
ATOM   6575  C CB  . ASP B 1 377 ? 153.118 144.731 165.563 1.00 63.29  ? 377 ASP B CB  1 
ATOM   6576  C CG  . ASP B 1 377 ? 154.364 145.528 165.897 1.00 63.29  ? 377 ASP B CG  1 
ATOM   6577  O OD1 . ASP B 1 377 ? 154.232 146.701 166.306 1.00 63.29  ? 377 ASP B OD1 1 
ATOM   6578  O OD2 . ASP B 1 377 ? 155.477 144.982 165.748 1.00 63.29  ? 377 ASP B OD2 1 
ATOM   6579  N N   . GLN B 1 378 ? 149.948 144.366 164.739 1.00 58.58  ? 378 GLN B N   1 
ATOM   6580  C CA  . GLN B 1 378 ? 148.900 143.613 164.060 1.00 58.58  ? 378 GLN B CA  1 
ATOM   6581  C C   . GLN B 1 378 ? 148.244 144.447 162.966 1.00 58.58  ? 378 GLN B C   1 
ATOM   6582  O O   . GLN B 1 378 ? 147.944 143.935 161.881 1.00 58.58  ? 378 GLN B O   1 
ATOM   6583  C CB  . GLN B 1 378 ? 147.856 143.138 165.068 1.00 58.58  ? 378 GLN B CB  1 
ATOM   6584  C CG  . GLN B 1 378 ? 148.223 141.850 165.772 1.00 58.58  ? 378 GLN B CG  1 
ATOM   6585  C CD  . GLN B 1 378 ? 147.376 141.598 167.001 1.00 58.58  ? 378 GLN B CD  1 
ATOM   6586  O OE1 . GLN B 1 378 ? 146.269 141.072 166.908 1.00 58.58  ? 378 GLN B OE1 1 
ATOM   6587  N NE2 . GLN B 1 378 ? 147.894 141.976 168.163 1.00 58.58  ? 378 GLN B NE2 1 
ATOM   6588  N N   . ILE B 1 379 ? 148.010 145.733 163.235 1.00 57.29  ? 379 ILE B N   1 
ATOM   6589  C CA  . ILE B 1 379 ? 147.313 146.583 162.275 1.00 57.29  ? 379 ILE B CA  1 
ATOM   6590  C C   . ILE B 1 379 ? 148.193 146.874 161.062 1.00 57.29  ? 379 ILE B C   1 
ATOM   6591  O O   . ILE B 1 379 ? 147.712 146.909 159.923 1.00 57.29  ? 379 ILE B O   1 
ATOM   6592  C CB  . ILE B 1 379 ? 146.838 147.874 162.968 1.00 57.29  ? 379 ILE B CB  1 
ATOM   6593  C CG1 . ILE B 1 379 ? 145.640 147.570 163.871 1.00 57.29  ? 379 ILE B CG1 1 
ATOM   6594  C CG2 . ILE B 1 379 ? 146.480 148.941 161.949 1.00 57.29  ? 379 ILE B CG2 1 
ATOM   6595  C CD1 . ILE B 1 379 ? 145.201 148.734 164.723 1.00 57.29  ? 379 ILE B CD1 1 
ATOM   6596  N N   . ASN B 1 380 ? 149.489 147.077 161.279 1.00 58.46  ? 380 ASN B N   1 
ATOM   6597  C CA  . ASN B 1 380 ? 150.378 147.469 160.192 1.00 58.46  ? 380 ASN B CA  1 
ATOM   6598  C C   . ASN B 1 380 ? 150.583 146.321 159.210 1.00 58.46  ? 380 ASN B C   1 
ATOM   6599  O O   . ASN B 1 380 ? 150.815 145.178 159.612 1.00 58.46  ? 380 ASN B O   1 
ATOM   6600  C CB  . ASN B 1 380 ? 151.723 147.927 160.752 1.00 58.46  ? 380 ASN B CB  1 
ATOM   6601  C CG  . ASN B 1 380 ? 151.765 149.417 161.019 1.00 58.46  ? 380 ASN B CG  1 
ATOM   6602  O OD1 . ASN B 1 380 ? 150.802 150.134 160.749 1.00 58.46  ? 380 ASN B OD1 1 
ATOM   6603  N ND2 . ASN B 1 380 ? 152.885 149.892 161.552 1.00 58.46  ? 380 ASN B ND2 1 
ATOM   6604  N N   . GLY B 1 381 ? 150.497 146.633 157.917 1.00 53.74  ? 381 GLY B N   1 
ATOM   6605  C CA  . GLY B 1 381 ? 150.760 145.654 156.881 1.00 53.74  ? 381 GLY B CA  1 
ATOM   6606  C C   . GLY B 1 381 ? 149.704 144.587 156.714 1.00 53.74  ? 381 GLY B C   1 
ATOM   6607  O O   . GLY B 1 381 ? 150.005 143.511 156.194 1.00 53.74  ? 381 GLY B O   1 
ATOM   6608  N N   . LYS B 1 382 ? 148.467 144.854 157.137 1.00 49.63  ? 382 LYS B N   1 
ATOM   6609  C CA  . LYS B 1 382 ? 147.431 143.828 157.081 1.00 49.63  ? 382 LYS B CA  1 
ATOM   6610  C C   . LYS B 1 382 ? 147.014 143.522 155.647 1.00 49.63  ? 382 LYS B C   1 
ATOM   6611  O O   . LYS B 1 382 ? 146.852 142.352 155.281 1.00 49.63  ? 382 LYS B O   1 
ATOM   6612  C CB  . LYS B 1 382 ? 146.224 144.258 157.913 1.00 49.63  ? 382 LYS B CB  1 
ATOM   6613  C CG  . LYS B 1 382 ? 145.585 143.117 158.679 1.00 49.63  ? 382 LYS B CG  1 
ATOM   6614  C CD  . LYS B 1 382 ? 145.130 143.552 160.057 1.00 49.63  ? 382 LYS B CD  1 
ATOM   6615  C CE  . LYS B 1 382 ? 143.871 144.381 159.973 1.00 49.63  ? 382 LYS B CE  1 
ATOM   6616  N NZ  . LYS B 1 382 ? 142.662 143.522 159.870 1.00 49.63  ? 382 LYS B NZ  1 
ATOM   6617  N N   . LEU B 1 383 ? 146.839 144.553 154.819 1.00 48.27  ? 383 LEU B N   1 
ATOM   6618  C CA  . LEU B 1 383 ? 146.332 144.338 153.468 1.00 48.27  ? 383 LEU B CA  1 
ATOM   6619  C C   . LEU B 1 383 ? 147.345 143.652 152.561 1.00 48.27  ? 383 LEU B C   1 
ATOM   6620  O O   . LEU B 1 383 ? 146.945 142.995 151.595 1.00 48.27  ? 383 LEU B O   1 
ATOM   6621  C CB  . LEU B 1 383 ? 145.896 145.667 152.851 1.00 48.27  ? 383 LEU B CB  1 
ATOM   6622  C CG  . LEU B 1 383 ? 144.799 145.567 151.791 1.00 48.27  ? 383 LEU B CG  1 
ATOM   6623  C CD1 . LEU B 1 383 ? 143.480 145.155 152.419 1.00 48.27  ? 383 LEU B CD1 1 
ATOM   6624  C CD2 . LEU B 1 383 ? 144.655 146.879 151.047 1.00 48.27  ? 383 LEU B CD2 1 
ATOM   6625  N N   . ASN B 1 384 ? 148.641 143.780 152.849 1.00 50.55  ? 384 ASN B N   1 
ATOM   6626  C CA  . ASN B 1 384 ? 149.651 143.112 152.037 1.00 50.55  ? 384 ASN B CA  1 
ATOM   6627  C C   . ASN B 1 384 ? 149.631 141.599 152.208 1.00 50.55  ? 384 ASN B C   1 
ATOM   6628  O O   . ASN B 1 384 ? 150.231 140.889 151.394 1.00 50.55  ? 384 ASN B O   1 
ATOM   6629  C CB  . ASN B 1 384 ? 151.041 143.650 152.379 1.00 50.55  ? 384 ASN B CB  1 
ATOM   6630  C CG  . ASN B 1 384 ? 151.163 145.142 152.145 1.00 50.55  ? 384 ASN B CG  1 
ATOM   6631  O OD1 . ASN B 1 384 ? 150.563 145.688 151.220 1.00 50.55  ? 384 ASN B OD1 1 
ATOM   6632  N ND2 . ASN B 1 384 ? 151.939 145.811 152.988 1.00 50.55  ? 384 ASN B ND2 1 
ATOM   6633  N N   . ARG B 1 385 ? 148.963 141.090 153.245 1.00 49.61  ? 385 ARG B N   1 
ATOM   6634  C CA  . ARG B 1 385 ? 148.940 139.649 153.475 1.00 49.61  ? 385 ARG B CA  1 
ATOM   6635  C C   . ARG B 1 385 ? 148.050 138.926 152.471 1.00 49.61  ? 385 ARG B C   1 
ATOM   6636  O O   . ARG B 1 385 ? 148.271 137.743 152.191 1.00 49.61  ? 385 ARG B O   1 
ATOM   6637  C CB  . ARG B 1 385 ? 148.472 139.351 154.899 1.00 49.61  ? 385 ARG B CB  1 
ATOM   6638  C CG  . ARG B 1 385 ? 149.563 139.449 155.952 1.00 49.61  ? 385 ARG B CG  1 
ATOM   6639  C CD  . ARG B 1 385 ? 148.979 139.783 157.313 1.00 49.61  ? 385 ARG B CD  1 
ATOM   6640  N NE  . ARG B 1 385 ? 149.898 140.572 158.123 1.00 49.61  ? 385 ARG B NE  1 
ATOM   6641  C CZ  . ARG B 1 385 ? 149.531 141.328 159.148 1.00 49.61  ? 385 ARG B CZ  1 
ATOM   6642  N NH1 . ARG B 1 385 ? 148.266 141.418 159.522 1.00 49.61  ? 385 ARG B NH1 1 
ATOM   6643  N NH2 . ARG B 1 385 ? 150.456 142.012 159.813 1.00 49.61  ? 385 ARG B NH2 1 
ATOM   6644  N N   . VAL B 1 386 ? 147.050 139.608 151.924 1.00 46.34  ? 386 VAL B N   1 
ATOM   6645  C CA  . VAL B 1 386 ? 146.046 138.991 151.068 1.00 46.34  ? 386 VAL B CA  1 
ATOM   6646  C C   . VAL B 1 386 ? 146.215 139.411 149.611 1.00 46.34  ? 386 VAL B C   1 
ATOM   6647  O O   . VAL B 1 386 ? 146.200 138.572 148.710 1.00 46.34  ? 386 VAL B O   1 
ATOM   6648  C CB  . VAL B 1 386 ? 144.621 139.306 151.576 1.00 46.34  ? 386 VAL B CB  1 
ATOM   6649  C CG1 . VAL B 1 386 ? 143.583 138.905 150.541 1.00 46.34  ? 386 VAL B CG1 1 
ATOM   6650  C CG2 . VAL B 1 386 ? 144.367 138.601 152.897 1.00 46.34  ? 386 VAL B CG2 1 
ATOM   6651  N N   . ILE B 1 387 ? 146.382 140.705 149.363 1.00 48.82  ? 387 ILE B N   1 
ATOM   6652  C CA  . ILE B 1 387 ? 146.409 141.243 148.007 1.00 48.82  ? 387 ILE B CA  1 
ATOM   6653  C C   . ILE B 1 387 ? 147.850 141.514 147.595 1.00 48.82  ? 387 ILE B C   1 
ATOM   6654  O O   . ILE B 1 387 ? 148.690 141.900 148.417 1.00 48.82  ? 387 ILE B O   1 
ATOM   6655  C CB  . ILE B 1 387 ? 145.534 142.510 147.896 1.00 48.82  ? 387 ILE B CB  1 
ATOM   6656  C CG1 . ILE B 1 387 ? 145.156 142.777 146.438 1.00 48.82  ? 387 ILE B CG1 1 
ATOM   6657  C CG2 . ILE B 1 387 ? 146.218 143.721 148.516 1.00 48.82  ? 387 ILE B CG2 1 
ATOM   6658  C CD1 . ILE B 1 387 ? 143.691 143.089 146.237 1.00 48.82  ? 387 ILE B CD1 1 
ATOM   6659  N N   . GLU B 1 388 ? 148.141 141.278 146.319 1.00 53.69  ? 388 GLU B N   1 
ATOM   6660  C CA  . GLU B 1 388 ? 149.472 141.456 145.761 1.00 53.69  ? 388 GLU B CA  1 
ATOM   6661  C C   . GLU B 1 388 ? 149.783 142.939 145.576 1.00 53.69  ? 388 GLU B C   1 
ATOM   6662  O O   . GLU B 1 388 ? 148.887 143.780 145.465 1.00 53.69  ? 388 GLU B O   1 
ATOM   6663  C CB  . GLU B 1 388 ? 149.597 140.715 144.428 1.00 53.69  ? 388 GLU B CB  1 
ATOM   6664  C CG  . GLU B 1 388 ? 148.800 139.419 144.358 1.00 53.69  ? 388 GLU B CG  1 
ATOM   6665  C CD  . GLU B 1 388 ? 147.354 139.639 143.940 1.00 53.69  ? 388 GLU B CD  1 
ATOM   6666  O OE1 . GLU B 1 388 ? 147.051 140.719 143.393 1.00 53.69  ? 388 GLU B OE1 1 
ATOM   6667  O OE2 . GLU B 1 388 ? 146.520 138.738 144.170 1.00 53.69  ? 388 GLU B OE2 1 
ATOM   6668  N N   . LYS B 1 389 ? 151.080 143.255 145.543 1.00 58.13  ? 389 LYS B N   1 
ATOM   6669  C CA  . LYS B 1 389 ? 151.506 144.652 145.526 1.00 58.13  ? 389 LYS B CA  1 
ATOM   6670  C C   . LYS B 1 389 ? 151.105 145.343 144.227 1.00 58.13  ? 389 LYS B C   1 
ATOM   6671  O O   . LYS B 1 389 ? 150.301 146.282 144.232 1.00 58.13  ? 389 LYS B O   1 
ATOM   6672  C CB  . LYS B 1 389 ? 153.020 144.738 145.737 1.00 58.13  ? 389 LYS B CB  1 
ATOM   6673  C CG  . LYS B 1 389 ? 153.513 146.120 146.149 1.00 58.13  ? 389 LYS B CG  1 
ATOM   6674  C CD  . LYS B 1 389 ? 155.006 146.110 146.443 1.00 58.13  ? 389 LYS B CD  1 
ATOM   6675  C CE  . LYS B 1 389 ? 155.499 147.484 146.869 1.00 58.13  ? 389 LYS B CE  1 
ATOM   6676  N NZ  . LYS B 1 389 ? 156.945 147.477 147.223 1.00 58.13  ? 389 LYS B NZ  1 
ATOM   6677  N N   . THR B 1 390 ? 151.649 144.888 143.100 1.00 53.81  ? 390 THR B N   1 
ATOM   6678  C CA  . THR B 1 390 ? 151.368 145.493 141.804 1.00 53.81  ? 390 THR B CA  1 
ATOM   6679  C C   . THR B 1 390 ? 151.372 144.417 140.733 1.00 53.81  ? 390 THR B C   1 
ATOM   6680  O O   . THR B 1 390 ? 152.320 143.633 140.642 1.00 53.81  ? 390 THR B O   1 
ATOM   6681  C CB  . THR B 1 390 ? 152.399 146.574 141.444 1.00 53.81  ? 390 THR B CB  1 
ATOM   6682  O OG1 . THR B 1 390 ? 153.707 146.153 141.855 1.00 53.81  ? 390 THR B OG1 1 
ATOM   6683  C CG2 . THR B 1 390 ? 152.055 147.903 142.103 1.00 53.81  ? 390 THR B CG2 1 
ATOM   6684  N N   . ASN B 1 391 ? 150.318 144.387 139.924 1.00 45.01  ? 391 ASN B N   1 
ATOM   6685  C CA  . ASN B 1 391 ? 150.241 143.512 138.762 1.00 45.01  ? 391 ASN B CA  1 
ATOM   6686  C C   . ASN B 1 391 ? 150.527 144.343 137.518 1.00 45.01  ? 391 ASN B C   1 
ATOM   6687  O O   . ASN B 1 391 ? 149.843 145.339 137.263 1.00 45.01  ? 391 ASN B O   1 
ATOM   6688  C CB  . ASN B 1 391 ? 148.872 142.836 138.669 1.00 45.01  ? 391 ASN B CB  1 
ATOM   6689  C CG  . ASN B 1 391 ? 147.722 143.824 138.770 1.00 45.01  ? 391 ASN B CG  1 
ATOM   6690  O OD1 . ASN B 1 391 ? 147.548 144.490 139.790 1.00 45.01  ? 391 ASN B OD1 1 
ATOM   6691  N ND2 . ASN B 1 391 ? 146.929 143.917 137.710 1.00 45.01  ? 391 ASN B ND2 1 
ATOM   6692  N N   . GLU B 1 392 ? 151.541 143.940 136.757 1.00 40.65  ? 392 GLU B N   1 
ATOM   6693  C CA  . GLU B 1 392 ? 151.940 144.656 135.552 1.00 40.65  ? 392 GLU B CA  1 
ATOM   6694  C C   . GLU B 1 392 ? 151.300 144.005 134.332 1.00 40.65  ? 392 GLU B C   1 
ATOM   6695  O O   . GLU B 1 392 ? 151.512 142.816 134.074 1.00 40.65  ? 392 GLU B O   1 
ATOM   6696  C CB  . GLU B 1 392 ? 153.461 144.672 135.410 1.00 40.65  ? 392 GLU B CB  1 
ATOM   6697  C CG  . GLU B 1 392 ? 154.115 145.905 135.988 1.00 40.65  ? 392 GLU B CG  1 
ATOM   6698  C CD  . GLU B 1 392 ? 155.542 146.093 135.514 1.00 40.65  ? 392 GLU B CD  1 
ATOM   6699  O OE1 . GLU B 1 392 ? 156.378 145.202 135.768 1.00 40.65  ? 392 GLU B OE1 1 
ATOM   6700  O OE2 . GLU B 1 392 ? 155.829 147.138 134.892 1.00 40.65  ? 392 GLU B OE2 1 
ATOM   6701  N N   . LYS B 1 393 ? 150.521 144.785 133.586 1.00 35.64  ? 393 LYS B N   1 
ATOM   6702  C CA  . LYS B 1 393 ? 149.918 144.352 132.334 1.00 35.64  ? 393 LYS B CA  1 
ATOM   6703  C C   . LYS B 1 393 ? 150.304 145.339 131.244 1.00 35.64  ? 393 LYS B C   1 
ATOM   6704  O O   . LYS B 1 393 ? 150.337 146.549 131.483 1.00 35.64  ? 393 LYS B O   1 
ATOM   6705  C CB  . LYS B 1 393 ? 148.392 144.257 132.447 1.00 35.64  ? 393 LYS B CB  1 
ATOM   6706  C CG  . LYS B 1 393 ? 147.901 143.589 133.718 1.00 35.64  ? 393 LYS B CG  1 
ATOM   6707  C CD  . LYS B 1 393 ? 147.846 142.081 133.567 1.00 35.64  ? 393 LYS B CD  1 
ATOM   6708  C CE  . LYS B 1 393 ? 147.543 141.408 134.895 1.00 35.64  ? 393 LYS B CE  1 
ATOM   6709  N NZ  . LYS B 1 393 ? 147.928 139.971 134.898 1.00 35.64  ? 393 LYS B NZ  1 
ATOM   6710  N N   . PHE B 1 394 ? 150.610 144.827 130.052 1.00 34.45  ? 394 PHE B N   1 
ATOM   6711  C CA  . PHE B 1 394 ? 151.124 145.684 128.991 1.00 34.45  ? 394 PHE B CA  1 
ATOM   6712  C C   . PHE B 1 394 ? 150.193 145.780 127.790 1.00 34.45  ? 394 PHE B C   1 
ATOM   6713  O O   . PHE B 1 394 ? 149.714 146.875 127.485 1.00 34.45  ? 394 PHE B O   1 
ATOM   6714  C CB  . PHE B 1 394 ? 152.509 145.181 128.572 1.00 34.45  ? 394 PHE B CB  1 
ATOM   6715  C CG  . PHE B 1 394 ? 153.501 145.165 129.696 1.00 34.45  ? 394 PHE B CG  1 
ATOM   6716  C CD1 . PHE B 1 394 ? 154.044 146.345 130.173 1.00 34.45  ? 394 PHE B CD1 1 
ATOM   6717  C CD2 . PHE B 1 394 ? 153.869 143.973 130.295 1.00 34.45  ? 394 PHE B CD2 1 
ATOM   6718  C CE1 . PHE B 1 394 ? 154.951 146.336 131.215 1.00 34.45  ? 394 PHE B CE1 1 
ATOM   6719  C CE2 . PHE B 1 394 ? 154.776 143.956 131.336 1.00 34.45  ? 394 PHE B CE2 1 
ATOM   6720  C CZ  . PHE B 1 394 ? 155.317 145.139 131.796 1.00 34.45  ? 394 PHE B CZ  1 
ATOM   6721  N N   . HIS B 1 395 ? 149.881 144.674 127.123 1.00 31.91  ? 395 HIS B N   1 
ATOM   6722  C CA  . HIS B 1 395 ? 149.035 144.698 125.937 1.00 31.91  ? 395 HIS B CA  1 
ATOM   6723  C C   . HIS B 1 395 ? 147.789 143.873 126.206 1.00 31.91  ? 395 HIS B C   1 
ATOM   6724  O O   . HIS B 1 395 ? 147.884 142.720 126.637 1.00 31.91  ? 395 HIS B O   1 
ATOM   6725  C CB  . HIS B 1 395 ? 149.774 144.170 124.705 1.00 31.91  ? 395 HIS B CB  1 
ATOM   6726  C CG  . HIS B 1 395 ? 149.004 144.327 123.430 1.00 31.91  ? 395 HIS B CG  1 
ATOM   6727  N ND1 . HIS B 1 395 ? 148.547 145.547 122.983 1.00 31.91  ? 395 HIS B ND1 1 
ATOM   6728  C CD2 . HIS B 1 395 ? 148.600 143.416 122.514 1.00 31.91  ? 395 HIS B CD2 1 
ATOM   6729  C CE1 . HIS B 1 395 ? 147.900 145.383 121.843 1.00 31.91  ? 395 HIS B CE1 1 
ATOM   6730  N NE2 . HIS B 1 395 ? 147.916 144.098 121.537 1.00 31.91  ? 395 HIS B NE2 1 
ATOM   6731  N N   . GLN B 1 396 ? 146.627 144.465 125.949 1.00 31.84  ? 396 GLN B N   1 
ATOM   6732  C CA  . GLN B 1 396 ? 145.348 143.867 126.300 1.00 31.84  ? 396 GLN B CA  1 
ATOM   6733  C C   . GLN B 1 396 ? 144.403 144.035 125.115 1.00 31.84  ? 396 GLN B C   1 
ATOM   6734  O O   . GLN B 1 396 ? 144.818 144.389 124.009 1.00 31.84  ? 396 GLN B O   1 
ATOM   6735  C CB  . GLN B 1 396 ? 144.793 144.498 127.586 1.00 31.84  ? 396 GLN B CB  1 
ATOM   6736  C CG  . GLN B 1 396 ? 145.625 144.211 128.828 1.00 31.84  ? 396 GLN B CG  1 
ATOM   6737  C CD  . GLN B 1 396 ? 145.403 145.223 129.935 1.00 31.84  ? 396 GLN B CD  1 
ATOM   6738  O OE1 . GLN B 1 396 ? 144.401 145.173 130.646 1.00 31.84  ? 396 GLN B OE1 1 
ATOM   6739  N NE2 . GLN B 1 396 ? 146.340 146.150 130.085 1.00 31.84  ? 396 GLN B NE2 1 
ATOM   6740  N N   . ILE B 1 397 ? 143.121 143.771 125.351 1.00 29.24  ? 397 ILE B N   1 
ATOM   6741  C CA  . ILE B 1 397 ? 142.093 143.919 124.328 1.00 29.24  ? 397 ILE B CA  1 
ATOM   6742  C C   . ILE B 1 397 ? 141.646 145.373 124.265 1.00 29.24  ? 397 ILE B C   1 
ATOM   6743  O O   . ILE B 1 397 ? 141.943 146.165 125.165 1.00 29.24  ? 397 ILE B O   1 
ATOM   6744  C CB  . ILE B 1 397 ? 140.896 142.991 124.605 1.00 29.24  ? 397 ILE B CB  1 
ATOM   6745  C CG1 . ILE B 1 397 ? 140.275 143.317 125.966 1.00 29.24  ? 397 ILE B CG1 1 
ATOM   6746  C CG2 . ILE B 1 397 ? 141.322 141.535 124.541 1.00 29.24  ? 397 ILE B CG2 1 
ATOM   6747  C CD1 . ILE B 1 397 ? 138.871 142.795 126.141 1.00 29.24  ? 397 ILE B CD1 1 
ATOM   6748  N N   . GLU B 1 398 ? 140.943 145.734 123.196 1.00 30.23  ? 398 GLU B N   1 
ATOM   6749  C CA  . GLU B 1 398 ? 140.307 147.039 123.111 1.00 30.23  ? 398 GLU B CA  1 
ATOM   6750  C C   . GLU B 1 398 ? 139.067 147.076 123.994 1.00 30.23  ? 398 GLU B C   1 
ATOM   6751  O O   . GLU B 1 398 ? 138.367 146.074 124.160 1.00 30.23  ? 398 GLU B O   1 
ATOM   6752  C CB  . GLU B 1 398 ? 139.931 147.364 121.665 1.00 30.23  ? 398 GLU B CB  1 
ATOM   6753  C CG  . GLU B 1 398 ? 141.121 147.583 120.751 1.00 30.23  ? 398 GLU B CG  1 
ATOM   6754  C CD  . GLU B 1 398 ? 141.981 148.750 121.186 1.00 30.23  ? 398 GLU B CD  1 
ATOM   6755  O OE1 . GLU B 1 398 ? 141.428 149.843 121.418 1.00 30.23  ? 398 GLU B OE1 1 
ATOM   6756  O OE2 . GLU B 1 398 ? 143.211 148.576 121.301 1.00 30.23  ? 398 GLU B OE2 1 
ATOM   6757  N N   . LYS B 1 399 ? 138.796 148.248 124.564 1.00 29.05  ? 399 LYS B N   1 
ATOM   6758  C CA  . LYS B 1 399 ? 137.686 148.404 125.491 1.00 29.05  ? 399 LYS B CA  1 
ATOM   6759  C C   . LYS B 1 399 ? 136.730 149.536 125.138 1.00 29.05  ? 399 LYS B C   1 
ATOM   6760  O O   . LYS B 1 399 ? 135.698 149.667 125.802 1.00 29.05  ? 399 LYS B O   1 
ATOM   6761  C CB  . LYS B 1 399 ? 138.213 148.607 126.920 1.00 29.05  ? 399 LYS B CB  1 
ATOM   6762  C CG  . LYS B 1 399 ? 138.834 147.346 127.500 1.00 29.05  ? 399 LYS B CG  1 
ATOM   6763  C CD  . LYS B 1 399 ? 139.648 147.608 128.752 1.00 29.05  ? 399 LYS B CD  1 
ATOM   6764  C CE  . LYS B 1 399 ? 140.482 146.388 129.110 1.00 29.05  ? 399 LYS B CE  1 
ATOM   6765  N NZ  . LYS B 1 399 ? 141.221 146.547 130.388 1.00 29.05  ? 399 LYS B NZ  1 
ATOM   6766  N N   . GLU B 1 400 ? 137.030 150.344 124.125 1.00 32.91  ? 400 GLU B N   1 
ATOM   6767  C CA  . GLU B 1 400 ? 136.121 151.361 123.617 1.00 32.91  ? 400 GLU B CA  1 
ATOM   6768  C C   . GLU B 1 400 ? 136.075 151.257 122.101 1.00 32.91  ? 400 GLU B C   1 
ATOM   6769  O O   . GLU B 1 400 ? 137.101 151.013 121.459 1.00 32.91  ? 400 GLU B O   1 
ATOM   6770  C CB  . GLU B 1 400 ? 136.555 152.772 124.041 1.00 32.91  ? 400 GLU B CB  1 
ATOM   6771  C CG  . GLU B 1 400 ? 136.187 153.137 125.468 1.00 32.91  ? 400 GLU B CG  1 
ATOM   6772  C CD  . GLU B 1 400 ? 136.679 154.518 125.865 1.00 32.91  ? 400 GLU B CD  1 
ATOM   6773  O OE1 . GLU B 1 400 ? 136.688 155.422 125.004 1.00 32.91  ? 400 GLU B OE1 1 
ATOM   6774  O OE2 . GLU B 1 400 ? 137.056 154.700 127.040 1.00 32.91  ? 400 GLU B OE2 1 
ATOM   6775  N N   . PHE B 1 401 ? 134.888 151.436 121.529 1.00 33.17  ? 401 PHE B N   1 
ATOM   6776  C CA  . PHE B 1 401 ? 134.675 151.225 120.106 1.00 33.17  ? 401 PHE B CA  1 
ATOM   6777  C C   . PHE B 1 401 ? 133.937 152.408 119.499 1.00 33.17  ? 401 PHE B C   1 
ATOM   6778  O O   . PHE B 1 401 ? 133.088 153.029 120.143 1.00 33.17  ? 401 PHE B O   1 
ATOM   6779  C CB  . PHE B 1 401 ? 133.891 149.930 119.850 1.00 33.17  ? 401 PHE B CB  1 
ATOM   6780  C CG  . PHE B 1 401 ? 134.488 148.724 120.517 1.00 33.17  ? 401 PHE B CG  1 
ATOM   6781  C CD1 . PHE B 1 401 ? 134.134 148.385 121.813 1.00 33.17  ? 401 PHE B CD1 1 
ATOM   6782  C CD2 . PHE B 1 401 ? 135.414 147.938 119.853 1.00 33.17  ? 401 PHE B CD2 1 
ATOM   6783  C CE1 . PHE B 1 401 ? 134.688 147.282 122.431 1.00 33.17  ? 401 PHE B CE1 1 
ATOM   6784  C CE2 . PHE B 1 401 ? 135.972 146.833 120.468 1.00 33.17  ? 401 PHE B CE2 1 
ATOM   6785  C CZ  . PHE B 1 401 ? 135.606 146.505 121.758 1.00 33.17  ? 401 PHE B CZ  1 
ATOM   6786  N N   . SER B 1 402 ? 134.266 152.709 118.243 1.00 38.30  ? 402 SER B N   1 
ATOM   6787  C CA  . SER B 1 402 ? 133.651 153.820 117.530 1.00 38.30  ? 402 SER B CA  1 
ATOM   6788  C C   . SER B 1 402 ? 132.591 153.388 116.525 1.00 38.30  ? 402 SER B C   1 
ATOM   6789  O O   . SER B 1 402 ? 131.747 154.209 116.154 1.00 38.30  ? 402 SER B O   1 
ATOM   6790  C CB  . SER B 1 402 ? 134.724 154.644 116.807 1.00 38.30  ? 402 SER B CB  1 
ATOM   6791  O OG  . SER B 1 402 ? 135.263 153.930 115.711 1.00 38.30  ? 402 SER B OG  1 
ATOM   6792  N N   . GLU B 1 403 ? 132.608 152.133 116.082 1.00 39.35  ? 403 GLU B N   1 
ATOM   6793  C CA  . GLU B 1 403 ? 131.626 151.621 115.137 1.00 39.35  ? 403 GLU B CA  1 
ATOM   6794  C C   . GLU B 1 403 ? 130.971 150.370 115.706 1.00 39.35  ? 403 GLU B C   1 
ATOM   6795  O O   . GLU B 1 403 ? 131.534 149.682 116.560 1.00 39.35  ? 403 GLU B O   1 
ATOM   6796  C CB  . GLU B 1 403 ? 132.255 151.301 113.772 1.00 39.35  ? 403 GLU B CB  1 
ATOM   6797  C CG  . GLU B 1 403 ? 133.501 152.106 113.432 1.00 39.35  ? 403 GLU B CG  1 
ATOM   6798  C CD  . GLU B 1 403 ? 133.202 153.559 113.106 1.00 39.35  ? 403 GLU B CD  1 
ATOM   6799  O OE1 . GLU B 1 403 ? 132.021 153.893 112.873 1.00 39.35  ? 403 GLU B OE1 1 
ATOM   6800  O OE2 . GLU B 1 403 ? 134.152 154.370 113.085 1.00 39.35  ? 403 GLU B OE2 1 
ATOM   6801  N N   . VAL B 1 404 ? 129.767 150.081 115.223 1.00 37.55  ? 404 VAL B N   1 
ATOM   6802  C CA  . VAL B 1 404 ? 129.040 148.880 115.614 1.00 37.55  ? 404 VAL B CA  1 
ATOM   6803  C C   . VAL B 1 404 ? 129.457 147.735 114.701 1.00 37.55  ? 404 VAL B C   1 
ATOM   6804  O O   . VAL B 1 404 ? 129.492 147.884 113.474 1.00 37.55  ? 404 VAL B O   1 
ATOM   6805  C CB  . VAL B 1 404 ? 127.519 149.108 115.565 1.00 37.55  ? 404 VAL B CB  1 
ATOM   6806  C CG1 . VAL B 1 404 ? 127.085 150.028 116.691 1.00 37.55  ? 404 VAL B CG1 1 
ATOM   6807  C CG2 . VAL B 1 404 ? 127.105 149.685 114.231 1.00 37.55  ? 404 VAL B CG2 1 
ATOM   6808  N N   . GLU B 1 405 ? 129.803 146.600 115.298 1.00 35.49  ? 405 GLU B N   1 
ATOM   6809  C CA  . GLU B 1 405 ? 130.293 145.450 114.549 1.00 35.49  ? 405 GLU B CA  1 
ATOM   6810  C C   . GLU B 1 405 ? 129.487 144.183 114.778 1.00 35.49  ? 405 GLU B C   1 
ATOM   6811  O O   . GLU B 1 405 ? 129.208 143.458 113.823 1.00 35.49  ? 405 GLU B O   1 
ATOM   6812  C CB  . GLU B 1 405 ? 131.761 145.185 114.903 1.00 35.49  ? 405 GLU B CB  1 
ATOM   6813  C CG  . GLU B 1 405 ? 132.671 146.377 114.695 1.00 35.49  ? 405 GLU B CG  1 
ATOM   6814  C CD  . GLU B 1 405 ? 134.096 146.100 115.127 1.00 35.49  ? 405 GLU B CD  1 
ATOM   6815  O OE1 . GLU B 1 405 ? 134.792 145.339 114.425 1.00 35.49  ? 405 GLU B OE1 1 
ATOM   6816  O OE2 . GLU B 1 405 ? 134.517 146.638 116.171 1.00 35.49  ? 405 GLU B OE2 1 
ATOM   6817  N N   . GLY B 1 406 ? 129.103 143.893 116.017 1.00 32.27  ? 406 GLY B N   1 
ATOM   6818  C CA  . GLY B 1 406 ? 128.316 142.707 116.293 1.00 32.27  ? 406 GLY B CA  1 
ATOM   6819  C C   . GLY B 1 406 ? 128.937 141.714 117.257 1.00 32.27  ? 406 GLY B C   1 
ATOM   6820  O O   . GLY B 1 406 ? 129.199 142.041 118.416 1.00 32.27  ? 406 GLY B O   1 
ATOM   6821  N N   . ARG B 1 407 ? 129.192 140.498 116.768 1.00 30.60  ? 407 ARG B N   1 
ATOM   6822  C CA  . ARG B 1 407 ? 129.453 139.356 117.643 1.00 30.60  ? 407 ARG B CA  1 
ATOM   6823  C C   . ARG B 1 407 ? 130.723 139.542 118.472 1.00 30.60  ? 407 ARG B C   1 
ATOM   6824  O O   . ARG B 1 407 ? 130.702 139.402 119.704 1.00 30.60  ? 407 ARG B O   1 
ATOM   6825  C CB  . ARG B 1 407 ? 129.538 138.087 116.792 1.00 30.60  ? 407 ARG B CB  1 
ATOM   6826  C CG  . ARG B 1 407 ? 129.113 136.813 117.487 1.00 30.60  ? 407 ARG B CG  1 
ATOM   6827  C CD  . ARG B 1 407 ? 129.200 135.628 116.537 1.00 30.60  ? 407 ARG B CD  1 
ATOM   6828  N NE  . ARG B 1 407 ? 129.096 134.355 117.239 1.00 30.60  ? 407 ARG B NE  1 
ATOM   6829  C CZ  . ARG B 1 407 ? 128.878 133.189 116.649 1.00 30.60  ? 407 ARG B CZ  1 
ATOM   6830  N NH1 . ARG B 1 407 ? 128.740 133.093 115.337 1.00 30.60  ? 407 ARG B NH1 1 
ATOM   6831  N NH2 . ARG B 1 407 ? 128.795 132.091 117.394 1.00 30.60  ? 407 ARG B NH2 1 
ATOM   6832  N N   . ILE B 1 408 ? 131.841 139.860 117.814 1.00 30.76  ? 408 ILE B N   1 
ATOM   6833  C CA  . ILE B 1 408 ? 133.122 139.957 118.511 1.00 30.76  ? 408 ILE B CA  1 
ATOM   6834  C C   . ILE B 1 408 ? 133.115 141.119 119.501 1.00 30.76  ? 408 ILE B C   1 
ATOM   6835  O O   . ILE B 1 408 ? 133.620 141.000 120.626 1.00 30.76  ? 408 ILE B O   1 
ATOM   6836  C CB  . ILE B 1 408 ? 134.274 140.084 117.496 1.00 30.76  ? 408 ILE B CB  1 
ATOM   6837  C CG1 . ILE B 1 408 ? 134.134 139.042 116.386 1.00 30.76  ? 408 ILE B CG1 1 
ATOM   6838  C CG2 . ILE B 1 408 ? 135.617 139.929 118.187 1.00 30.76  ? 408 ILE B CG2 1 
ATOM   6839  C CD1 . ILE B 1 408 ? 134.178 137.609 116.872 1.00 30.76  ? 408 ILE B CD1 1 
ATOM   6840  N N   . GLN B 1 409 ? 132.556 142.261 119.095 1.00 31.56  ? 409 GLN B N   1 
ATOM   6841  C CA  . GLN B 1 409 ? 132.461 143.405 119.996 1.00 31.56  ? 409 GLN B CA  1 
ATOM   6842  C C   . GLN B 1 409 ? 131.591 143.084 121.206 1.00 31.56  ? 409 GLN B C   1 
ATOM   6843  O O   . GLN B 1 409 ? 131.919 143.467 122.339 1.00 31.56  ? 409 GLN B O   1 
ATOM   6844  C CB  . GLN B 1 409 ? 131.912 144.616 119.240 1.00 31.56  ? 409 GLN B CB  1 
ATOM   6845  C CG  . GLN B 1 409 ? 131.995 145.918 120.011 1.00 31.56  ? 409 GLN B CG  1 
ATOM   6846  C CD  . GLN B 1 409 ? 131.539 147.112 119.197 1.00 31.56  ? 409 GLN B CD  1 
ATOM   6847  O OE1 . GLN B 1 409 ? 130.655 147.857 119.614 1.00 31.56  ? 409 GLN B OE1 1 
ATOM   6848  N NE2 . GLN B 1 409 ? 132.144 147.302 118.034 1.00 31.56  ? 409 GLN B NE2 1 
ATOM   6849  N N   . ASP B 1 410 ? 130.474 142.384 120.984 1.00 30.62  ? 410 ASP B N   1 
ATOM   6850  C CA  . ASP B 1 410 ? 129.626 141.958 122.092 1.00 30.62  ? 410 ASP B CA  1 
ATOM   6851  C C   . ASP B 1 410 ? 130.405 141.092 123.073 1.00 30.62  ? 410 ASP B C   1 
ATOM   6852  O O   . ASP B 1 410 ? 130.312 141.282 124.292 1.00 30.62  ? 410 ASP B O   1 
ATOM   6853  C CB  . ASP B 1 410 ? 128.410 141.194 121.565 1.00 30.62  ? 410 ASP B CB  1 
ATOM   6854  C CG  . ASP B 1 410 ? 127.424 142.085 120.837 1.00 30.62  ? 410 ASP B CG  1 
ATOM   6855  O OD1 . ASP B 1 410 ? 127.550 143.322 120.926 1.00 30.62  ? 410 ASP B OD1 1 
ATOM   6856  O OD2 . ASP B 1 410 ? 126.523 141.543 120.165 1.00 30.62  ? 410 ASP B OD2 1 
ATOM   6857  N N   . LEU B 1 411 ? 131.189 140.143 122.555 1.00 28.11  ? 411 LEU B N   1 
ATOM   6858  C CA  . LEU B 1 411 ? 131.964 139.269 123.432 1.00 28.11  ? 411 LEU B CA  1 
ATOM   6859  C C   . LEU B 1 411 ? 133.011 140.049 124.226 1.00 28.11  ? 411 LEU B C   1 
ATOM   6860  O O   . LEU B 1 411 ? 133.197 139.804 125.426 1.00 28.11  ? 411 LEU B O   1 
ATOM   6861  C CB  . LEU B 1 411 ? 132.615 138.157 122.610 1.00 28.11  ? 411 LEU B CB  1 
ATOM   6862  C CG  . LEU B 1 411 ? 133.287 137.009 123.363 1.00 28.11  ? 411 LEU B CG  1 
ATOM   6863  C CD1 . LEU B 1 411 ? 132.398 136.492 124.482 1.00 28.11  ? 411 LEU B CD1 1 
ATOM   6864  C CD2 . LEU B 1 411 ? 133.643 135.891 122.401 1.00 28.11  ? 411 LEU B CD2 1 
ATOM   6865  N N   . GLU B 1 412 ? 133.702 140.990 123.579 1.00 29.66  ? 412 GLU B N   1 
ATOM   6866  C CA  . GLU B 1 412 ? 134.719 141.776 124.277 1.00 29.66  ? 412 GLU B CA  1 
ATOM   6867  C C   . GLU B 1 412 ? 134.104 142.608 125.401 1.00 29.66  ? 412 GLU B C   1 
ATOM   6868  O O   . GLU B 1 412 ? 134.620 142.640 126.532 1.00 29.66  ? 412 GLU B O   1 
ATOM   6869  C CB  . GLU B 1 412 ? 135.460 142.668 123.279 1.00 29.66  ? 412 GLU B CB  1 
ATOM   6870  C CG  . GLU B 1 412 ? 136.418 141.912 122.377 1.00 29.66  ? 412 GLU B CG  1 
ATOM   6871  C CD  . GLU B 1 412 ? 136.675 142.616 121.059 1.00 29.66  ? 412 GLU B CD  1 
ATOM   6872  O OE1 . GLU B 1 412 ? 135.890 143.515 120.697 1.00 29.66  ? 412 GLU B OE1 1 
ATOM   6873  O OE2 . GLU B 1 412 ? 137.663 142.267 120.380 1.00 29.66  ? 412 GLU B OE2 1 
ATOM   6874  N N   . LYS B 1 413 ? 132.978 143.270 125.112 1.00 29.05  ? 413 LYS B N   1 
ATOM   6875  C CA  . LYS B 1 413 ? 132.302 144.060 126.136 1.00 29.05  ? 413 LYS B CA  1 
ATOM   6876  C C   . LYS B 1 413 ? 131.835 143.184 127.293 1.00 29.05  ? 413 LYS B C   1 
ATOM   6877  O O   . LYS B 1 413 ? 131.963 143.568 128.464 1.00 29.05  ? 413 LYS B O   1 
ATOM   6878  C CB  . LYS B 1 413 ? 131.122 144.814 125.524 1.00 29.05  ? 413 LYS B CB  1 
ATOM   6879  C CG  . LYS B 1 413 ? 131.520 146.036 124.718 1.00 29.05  ? 413 LYS B CG  1 
ATOM   6880  C CD  . LYS B 1 413 ? 130.359 146.554 123.885 1.00 29.05  ? 413 LYS B CD  1 
ATOM   6881  C CE  . LYS B 1 413 ? 130.645 147.940 123.343 1.00 29.05  ? 413 LYS B CE  1 
ATOM   6882  N NZ  . LYS B 1 413 ? 129.409 148.624 122.874 1.00 29.05  ? 413 LYS B NZ  1 
ATOM   6883  N N   . TYR B 1 414 ? 131.300 141.999 126.983 1.00 26.58  ? 414 TYR B N   1 
ATOM   6884  C CA  . TYR B 1 414 ? 130.823 141.098 128.028 1.00 26.58  ? 414 TYR B CA  1 
ATOM   6885  C C   . TYR B 1 414 ? 131.962 140.637 128.933 1.00 26.58  ? 414 TYR B C   1 
ATOM   6886  O O   . TYR B 1 414 ? 131.809 140.589 130.161 1.00 26.58  ? 414 TYR B O   1 
ATOM   6887  C CB  . TYR B 1 414 ? 130.118 139.906 127.382 1.00 26.58  ? 414 TYR B CB  1 
ATOM   6888  C CG  . TYR B 1 414 ? 129.408 138.978 128.338 1.00 26.58  ? 414 TYR B CG  1 
ATOM   6889  C CD1 . TYR B 1 414 ? 128.186 139.325 128.896 1.00 26.58  ? 414 TYR B CD1 1 
ATOM   6890  C CD2 . TYR B 1 414 ? 129.952 137.745 128.665 1.00 26.58  ? 414 TYR B CD2 1 
ATOM   6891  C CE1 . TYR B 1 414 ? 127.532 138.473 129.762 1.00 26.58  ? 414 TYR B CE1 1 
ATOM   6892  C CE2 . TYR B 1 414 ? 129.306 136.888 129.528 1.00 26.58  ? 414 TYR B CE2 1 
ATOM   6893  C CZ  . TYR B 1 414 ? 128.097 137.256 130.073 1.00 26.58  ? 414 TYR B CZ  1 
ATOM   6894  O OH  . TYR B 1 414 ? 127.454 136.403 130.932 1.00 26.58  ? 414 TYR B OH  1 
ATOM   6895  N N   . VAL B 1 415 ? 133.113 140.300 128.343 1.00 26.28  ? 415 VAL B N   1 
ATOM   6896  C CA  . VAL B 1 415 ? 134.264 139.857 129.131 1.00 26.28  ? 415 VAL B CA  1 
ATOM   6897  C C   . VAL B 1 415 ? 134.716 140.962 130.083 1.00 26.28  ? 415 VAL B C   1 
ATOM   6898  O O   . VAL B 1 415 ? 134.949 140.727 131.282 1.00 26.28  ? 415 VAL B O   1 
ATOM   6899  C CB  . VAL B 1 415 ? 135.406 139.409 128.199 1.00 26.28  ? 415 VAL B CB  1 
ATOM   6900  C CG1 . VAL B 1 415 ? 136.729 139.352 128.945 1.00 26.28  ? 415 VAL B CG1 1 
ATOM   6901  C CG2 . VAL B 1 415 ? 135.085 138.064 127.558 1.00 26.28  ? 415 VAL B CG2 1 
ATOM   6902  N N   . GLU B 1 416 ? 134.836 142.191 129.565 1.00 27.72  ? 416 GLU B N   1 
ATOM   6903  C CA  . GLU B 1 416 ? 135.280 143.292 130.417 1.00 27.72  ? 416 GLU B CA  1 
ATOM   6904  C C   . GLU B 1 416 ? 134.293 143.555 131.554 1.00 27.72  ? 416 GLU B C   1 
ATOM   6905  O O   . GLU B 1 416 ? 134.700 143.771 132.706 1.00 27.72  ? 416 GLU B O   1 
ATOM   6906  C CB  . GLU B 1 416 ? 135.496 144.551 129.578 1.00 27.72  ? 416 GLU B CB  1 
ATOM   6907  C CG  . GLU B 1 416 ? 136.186 145.695 130.310 1.00 27.72  ? 416 GLU B CG  1 
ATOM   6908  C CD  . GLU B 1 416 ? 137.496 145.289 130.969 1.00 27.72  ? 416 GLU B CD  1 
ATOM   6909  O OE1 . GLU B 1 416 ? 138.200 144.410 130.431 1.00 27.72  ? 416 GLU B OE1 1 
ATOM   6910  O OE2 . GLU B 1 416 ? 137.828 145.857 132.028 1.00 27.72  ? 416 GLU B OE2 1 
ATOM   6911  N N   . ASP B 1 417 ? 132.990 143.522 131.252 1.00 27.19  ? 417 ASP B N   1 
ATOM   6912  C CA  . ASP B 1 417 ? 131.978 143.747 132.283 1.00 27.19  ? 417 ASP B CA  1 
ATOM   6913  C C   . ASP B 1 417 ? 132.043 142.687 133.380 1.00 27.19  ? 417 ASP B C   1 
ATOM   6914  O O   . ASP B 1 417 ? 131.952 143.008 134.576 1.00 27.19  ? 417 ASP B O   1 
ATOM   6915  C CB  . ASP B 1 417 ? 130.592 143.771 131.644 1.00 27.19  ? 417 ASP B CB  1 
ATOM   6916  C CG  . ASP B 1 417 ? 129.563 144.451 132.515 1.00 27.19  ? 417 ASP B CG  1 
ATOM   6917  O OD1 . ASP B 1 417 ? 129.722 145.658 132.788 1.00 27.19  ? 417 ASP B OD1 1 
ATOM   6918  O OD2 . ASP B 1 417 ? 128.596 143.778 132.926 1.00 27.19  ? 417 ASP B OD2 1 
ATOM   6919  N N   . THR B 1 418 ? 132.198 141.417 132.992 1.00 24.85  ? 418 THR B N   1 
ATOM   6920  C CA  . THR B 1 418 ? 132.301 140.342 133.975 1.00 24.85  ? 418 THR B CA  1 
ATOM   6921  C C   . THR B 1 418 ? 133.490 140.561 134.904 1.00 24.85  ? 418 THR B C   1 
ATOM   6922  O O   . THR B 1 418 ? 133.371 140.442 136.137 1.00 24.85  ? 418 THR B O   1 
ATOM   6923  C CB  . THR B 1 418 ? 132.418 138.995 133.257 1.00 24.85  ? 418 THR B CB  1 
ATOM   6924  O OG1 . THR B 1 418 ? 131.252 138.774 132.455 1.00 24.85  ? 418 THR B OG1 1 
ATOM   6925  C CG2 . THR B 1 418 ? 132.569 137.854 134.252 1.00 24.85  ? 418 THR B CG2 1 
ATOM   6926  N N   . LYS B 1 419 ? 134.648 140.898 134.325 1.00 23.95  ? 419 LYS B N   1 
ATOM   6927  C CA  . LYS B 1 419 ? 135.842 141.100 135.141 1.00 23.95  ? 419 LYS B CA  1 
ATOM   6928  C C   . LYS B 1 419 ? 135.654 142.246 136.132 1.00 23.95  ? 419 LYS B C   1 
ATOM   6929  O O   . LYS B 1 419 ? 136.000 142.120 137.320 1.00 23.95  ? 419 LYS B O   1 
ATOM   6930  C CB  . LYS B 1 419 ? 137.045 141.352 134.234 1.00 23.95  ? 419 LYS B CB  1 
ATOM   6931  C CG  . LYS B 1 419 ? 138.298 141.814 134.942 1.00 23.95  ? 419 LYS B CG  1 
ATOM   6932  C CD  . LYS B 1 419 ? 139.426 141.995 133.949 1.00 23.95  ? 419 LYS B CD  1 
ATOM   6933  C CE  . LYS B 1 419 ? 140.780 141.954 134.625 1.00 23.95  ? 419 LYS B CE  1 
ATOM   6934  N NZ  . LYS B 1 419 ? 141.594 143.149 134.300 1.00 23.95  ? 419 LYS B NZ  1 
ATOM   6935  N N   . VAL B 1 420 ? 135.090 143.365 135.665 1.00 24.06  ? 420 VAL B N   1 
ATOM   6936  C CA  . VAL B 1 420 ? 134.909 144.526 136.535 1.00 24.06  ? 420 VAL B CA  1 
ATOM   6937  C C   . VAL B 1 420 ? 133.986 144.184 137.699 1.00 24.06  ? 420 VAL B C   1 
ATOM   6938  O O   . VAL B 1 420 ? 134.269 144.519 138.859 1.00 24.06  ? 420 VAL B O   1 
ATOM   6939  C CB  . VAL B 1 420 ? 134.382 145.726 135.728 1.00 24.06  ? 420 VAL B CB  1 
ATOM   6940  C CG1 . VAL B 1 420 ? 133.913 146.830 136.657 1.00 24.06  ? 420 VAL B CG1 1 
ATOM   6941  C CG2 . VAL B 1 420 ? 135.459 146.244 134.794 1.00 24.06  ? 420 VAL B CG2 1 
ATOM   6942  N N   . ASP B 1 421 ? 132.871 143.506 137.411 1.00 25.93  ? 421 ASP B N   1 
ATOM   6943  C CA  . ASP B 1 421 ? 131.931 143.168 138.476 1.00 25.93  ? 421 ASP B CA  1 
ATOM   6944  C C   . ASP B 1 421 ? 132.575 142.269 139.530 1.00 25.93  ? 421 ASP B C   1 
ATOM   6945  O O   . ASP B 1 421 ? 132.426 142.508 140.742 1.00 25.93  ? 421 ASP B O   1 
ATOM   6946  C CB  . ASP B 1 421 ? 130.689 142.503 137.886 1.00 25.93  ? 421 ASP B CB  1 
ATOM   6947  C CG  . ASP B 1 421 ? 129.751 143.499 137.235 1.00 25.93  ? 421 ASP B CG  1 
ATOM   6948  O OD1 . ASP B 1 421 ? 129.876 144.708 137.515 1.00 25.93  ? 421 ASP B OD1 1 
ATOM   6949  O OD2 . ASP B 1 421 ? 128.886 143.076 136.442 1.00 25.93  ? 421 ASP B OD2 1 
ATOM   6950  N N   . LEU B 1 422 ? 133.312 141.242 139.092 1.00 22.86  ? 422 LEU B N   1 
ATOM   6951  C CA  . LEU B 1 422 ? 133.915 140.332 140.063 1.00 22.86  ? 422 LEU B CA  1 
ATOM   6952  C C   . LEU B 1 422 ? 134.943 141.049 140.940 1.00 22.86  ? 422 LEU B C   1 
ATOM   6953  O O   . LEU B 1 422 ? 134.975 140.846 142.165 1.00 22.86  ? 422 LEU B O   1 
ATOM   6954  C CB  . LEU B 1 422 ? 134.533 139.130 139.348 1.00 22.86  ? 422 LEU B CB  1 
ATOM   6955  C CG  . LEU B 1 422 ? 133.516 138.077 138.887 1.00 22.86  ? 422 LEU B CG  1 
ATOM   6956  C CD1 . LEU B 1 422 ? 134.058 137.226 137.748 1.00 22.86  ? 422 LEU B CD1 1 
ATOM   6957  C CD2 . LEU B 1 422 ? 133.056 137.199 140.044 1.00 22.86  ? 422 LEU B CD2 1 
ATOM   6958  N N   . TRP B 1 423 ? 135.771 141.918 140.348 1.00 22.96  ? 423 TRP B N   1 
ATOM   6959  C CA  . TRP B 1 423 ? 136.767 142.600 141.175 1.00 22.96  ? 423 TRP B CA  1 
ATOM   6960  C C   . TRP B 1 423 ? 136.133 143.608 142.135 1.00 22.96  ? 423 TRP B C   1 
ATOM   6961  O O   . TRP B 1 423 ? 136.620 143.771 143.265 1.00 22.96  ? 423 TRP B O   1 
ATOM   6962  C CB  . TRP B 1 423 ? 137.830 143.265 140.300 1.00 22.96  ? 423 TRP B CB  1 
ATOM   6963  C CG  . TRP B 1 423 ? 138.935 142.316 139.943 1.00 22.96  ? 423 TRP B CG  1 
ATOM   6964  C CD1 . TRP B 1 423 ? 139.235 141.839 138.703 1.00 22.96  ? 423 TRP B CD1 1 
ATOM   6965  C CD2 . TRP B 1 423 ? 139.864 141.699 140.845 1.00 22.96  ? 423 TRP B CD2 1 
ATOM   6966  N NE1 . TRP B 1 423 ? 140.299 140.977 138.772 1.00 22.96  ? 423 TRP B NE1 1 
ATOM   6967  C CE2 . TRP B 1 423 ? 140.704 140.872 140.076 1.00 22.96  ? 423 TRP B CE2 1 
ATOM   6968  C CE3 . TRP B 1 423 ? 140.070 141.770 142.227 1.00 22.96  ? 423 TRP B CE3 1 
ATOM   6969  C CZ2 . TRP B 1 423 ? 141.734 140.121 140.640 1.00 22.96  ? 423 TRP B CZ2 1 
ATOM   6970  C CZ3 . TRP B 1 423 ? 141.092 141.024 142.786 1.00 22.96  ? 423 TRP B CZ3 1 
ATOM   6971  C CH2 . TRP B 1 423 ? 141.910 140.211 141.994 1.00 22.96  ? 423 TRP B CH2 1 
ATOM   6972  N N   . SER B 1 424 ? 135.050 144.279 141.726 1.00 24.47  ? 424 SER B N   1 
ATOM   6973  C CA  . SER B 1 424 ? 134.363 145.182 142.649 1.00 24.47  ? 424 SER B CA  1 
ATOM   6974  C C   . SER B 1 424 ? 133.808 144.427 143.853 1.00 24.47  ? 424 SER B C   1 
ATOM   6975  O O   . SER B 1 424 ? 133.935 144.885 145.003 1.00 24.47  ? 424 SER B O   1 
ATOM   6976  C CB  . SER B 1 424 ? 133.241 145.927 141.926 1.00 24.47  ? 424 SER B CB  1 
ATOM   6977  O OG  . SER B 1 424 ? 133.733 146.649 140.816 1.00 24.47  ? 424 SER B OG  1 
ATOM   6978  N N   . TYR B 1 425 ? 133.197 143.261 143.611 1.00 25.09  ? 425 TYR B N   1 
ATOM   6979  C CA  . TYR B 1 425 ? 132.705 142.458 144.728 1.00 25.09  ? 425 TYR B CA  1 
ATOM   6980  C C   . TYR B 1 425 ? 133.847 142.044 145.655 1.00 25.09  ? 425 TYR B C   1 
ATOM   6981  O O   . TYR B 1 425 ? 133.707 142.088 146.889 1.00 25.09  ? 425 TYR B O   1 
ATOM   6982  C CB  . TYR B 1 425 ? 131.953 141.229 144.211 1.00 25.09  ? 425 TYR B CB  1 
ATOM   6983  C CG  . TYR B 1 425 ? 131.607 140.224 145.290 1.00 25.09  ? 425 TYR B CG  1 
ATOM   6984  C CD1 . TYR B 1 425 ? 130.428 140.331 146.014 1.00 25.09  ? 425 TYR B CD1 1 
ATOM   6985  C CD2 . TYR B 1 425 ? 132.459 139.166 145.581 1.00 25.09  ? 425 TYR B CD2 1 
ATOM   6986  C CE1 . TYR B 1 425 ? 130.112 139.420 147.000 1.00 25.09  ? 425 TYR B CE1 1 
ATOM   6987  C CE2 . TYR B 1 425 ? 132.153 138.255 146.565 1.00 25.09  ? 425 TYR B CE2 1 
ATOM   6988  C CZ  . TYR B 1 425 ? 130.978 138.384 147.270 1.00 25.09  ? 425 TYR B CZ  1 
ATOM   6989  O OH  . TYR B 1 425 ? 130.669 137.472 148.250 1.00 25.09  ? 425 TYR B OH  1 
ATOM   6990  N N   . ASN B 1 426 ? 134.984 141.642 145.076 1.00 24.76  ? 426 ASN B N   1 
ATOM   6991  C CA  . ASN B 1 426 ? 136.130 141.247 145.893 1.00 24.76  ? 426 ASN B CA  1 
ATOM   6992  C C   . ASN B 1 426 ? 136.581 142.385 146.803 1.00 24.76  ? 426 ASN B C   1 
ATOM   6993  O O   . ASN B 1 426 ? 136.822 142.181 148.000 1.00 24.76  ? 426 ASN B O   1 
ATOM   6994  C CB  . ASN B 1 426 ? 137.286 140.795 145.000 1.00 24.76  ? 426 ASN B CB  1 
ATOM   6995  C CG  . ASN B 1 426 ? 137.148 139.359 144.541 1.00 24.76  ? 426 ASN B CG  1 
ATOM   6996  O OD1 . ASN B 1 426 ? 136.370 138.586 145.094 1.00 24.76  ? 426 ASN B OD1 1 
ATOM   6997  N ND2 . ASN B 1 426 ? 137.915 138.993 143.525 1.00 24.76  ? 426 ASN B ND2 1 
ATOM   6998  N N   . ALA B 1 427 ? 136.700 143.595 146.247 1.00 27.20  ? 427 ALA B N   1 
ATOM   6999  C CA  . ALA B 1 427 ? 137.165 144.731 147.042 1.00 27.20  ? 427 ALA B CA  1 
ATOM   7000  C C   . ALA B 1 427 ? 136.208 145.047 148.189 1.00 27.20  ? 427 ALA B C   1 
ATOM   7001  O O   . ALA B 1 427 ? 136.643 145.269 149.332 1.00 27.20  ? 427 ALA B O   1 
ATOM   7002  C CB  . ALA B 1 427 ? 137.355 145.955 146.148 1.00 27.20  ? 427 ALA B CB  1 
ATOM   7003  N N   . GLU B 1 428 ? 134.901 145.061 147.906 1.00 31.39  ? 428 GLU B N   1 
ATOM   7004  C CA  . GLU B 1 428 ? 133.923 145.342 148.959 1.00 31.39  ? 428 GLU B CA  1 
ATOM   7005  C C   . GLU B 1 428 ? 134.024 144.328 150.100 1.00 31.39  ? 428 GLU B C   1 
ATOM   7006  O O   . GLU B 1 428 ? 134.119 144.702 151.285 1.00 31.39  ? 428 GLU B O   1 
ATOM   7007  C CB  . GLU B 1 428 ? 132.514 145.350 148.365 1.00 31.39  ? 428 GLU B CB  1 
ATOM   7008  C CG  . GLU B 1 428 ? 131.439 145.928 149.269 1.00 31.39  ? 428 GLU B CG  1 
ATOM   7009  C CD  . GLU B 1 428 ? 131.541 147.433 149.419 1.00 31.39  ? 428 GLU B CD  1 
ATOM   7010  O OE1 . GLU B 1 428 ? 131.306 148.151 148.426 1.00 31.39  ? 428 GLU B OE1 1 
ATOM   7011  O OE2 . GLU B 1 428 ? 131.845 147.900 150.536 1.00 31.39  ? 428 GLU B OE2 1 
ATOM   7012  N N   . LEU B 1 429 ? 134.017 143.034 149.758 1.00 30.43  ? 429 LEU B N   1 
ATOM   7013  C CA  . LEU B 1 429 ? 134.049 142.008 150.797 1.00 30.43  ? 429 LEU B CA  1 
ATOM   7014  C C   . LEU B 1 429 ? 135.334 142.085 151.613 1.00 30.43  ? 429 LEU B C   1 
ATOM   7015  O O   . LEU B 1 429 ? 135.306 141.950 152.846 1.00 30.43  ? 429 LEU B O   1 
ATOM   7016  C CB  . LEU B 1 429 ? 133.889 140.620 150.179 1.00 30.43  ? 429 LEU B CB  1 
ATOM   7017  C CG  . LEU B 1 429 ? 133.989 139.443 151.153 1.00 30.43  ? 429 LEU B CG  1 
ATOM   7018  C CD1 . LEU B 1 429 ? 132.812 139.434 152.117 1.00 30.43  ? 429 LEU B CD1 1 
ATOM   7019  C CD2 . LEU B 1 429 ? 134.084 138.124 150.410 1.00 30.43  ? 429 LEU B CD2 1 
ATOM   7020  N N   . LEU B 1 430 ? 136.470 142.307 150.944 1.00 31.35  ? 430 LEU B N   1 
ATOM   7021  C CA  . LEU B 1 430 ? 137.743 142.367 151.653 1.00 31.35  ? 430 LEU B CA  1 
ATOM   7022  C C   . LEU B 1 430 ? 137.766 143.512 152.655 1.00 31.35  ? 430 LEU B C   1 
ATOM   7023  O O   . LEU B 1 430 ? 138.216 143.338 153.797 1.00 31.35  ? 430 LEU B O   1 
ATOM   7024  C CB  . LEU B 1 430 ? 138.892 142.507 150.657 1.00 31.35  ? 430 LEU B CB  1 
ATOM   7025  C CG  . LEU B 1 430 ? 140.283 142.690 151.266 1.00 31.35  ? 430 LEU B CG  1 
ATOM   7026  C CD1 . LEU B 1 430 ? 140.673 141.474 152.088 1.00 31.35  ? 430 LEU B CD1 1 
ATOM   7027  C CD2 . LEU B 1 430 ? 141.311 142.956 150.185 1.00 31.35  ? 430 LEU B CD2 1 
ATOM   7028  N N   . VAL B 1 431 ? 137.285 144.693 152.250 1.00 32.51  ? 431 VAL B N   1 
ATOM   7029  C CA  . VAL B 1 431 ? 137.289 145.824 153.175 1.00 32.51  ? 431 VAL B CA  1 
ATOM   7030  C C   . VAL B 1 431 ? 136.425 145.521 154.395 1.00 32.51  ? 431 VAL B C   1 
ATOM   7031  O O   . VAL B 1 431 ? 136.834 145.772 155.542 1.00 32.51  ? 431 VAL B O   1 
ATOM   7032  C CB  . VAL B 1 431 ? 136.837 147.111 152.459 1.00 32.51  ? 431 VAL B CB  1 
ATOM   7033  C CG1 . VAL B 1 431 ? 136.516 148.200 153.468 1.00 32.51  ? 431 VAL B CG1 1 
ATOM   7034  C CG2 . VAL B 1 431 ? 137.915 147.584 151.503 1.00 32.51  ? 431 VAL B CG2 1 
ATOM   7035  N N   . ALA B 1 432 ? 135.229 144.962 154.176 1.00 35.27  ? 432 ALA B N   1 
ATOM   7036  C CA  . ALA B 1 432 ? 134.348 144.675 155.309 1.00 35.27  ? 432 ALA B CA  1 
ATOM   7037  C C   . ALA B 1 432 ? 134.991 143.685 156.282 1.00 35.27  ? 432 ALA B C   1 
ATOM   7038  O O   . ALA B 1 432 ? 134.985 143.898 157.507 1.00 35.27  ? 432 ALA B O   1 
ATOM   7039  C CB  . ALA B 1 432 ? 133.004 144.150 154.808 1.00 35.27  ? 432 ALA B CB  1 
ATOM   7040  N N   . LEU B 1 433 ? 135.573 142.606 155.750 1.00 36.79  ? 433 LEU B N   1 
ATOM   7041  C CA  . LEU B 1 433 ? 136.199 141.596 156.602 1.00 36.79  ? 433 LEU B CA  1 
ATOM   7042  C C   . LEU B 1 433 ? 137.352 142.183 157.410 1.00 36.79  ? 433 LEU B C   1 
ATOM   7043  O O   . LEU B 1 433 ? 137.481 141.931 158.620 1.00 36.79  ? 433 LEU B O   1 
ATOM   7044  C CB  . LEU B 1 433 ? 136.694 140.430 155.747 1.00 36.79  ? 433 LEU B CB  1 
ATOM   7045  C CG  . LEU B 1 433 ? 135.808 139.195 155.629 1.00 36.79  ? 433 LEU B CG  1 
ATOM   7046  C CD1 . LEU B 1 433 ? 136.465 138.178 154.711 1.00 36.79  ? 433 LEU B CD1 1 
ATOM   7047  C CD2 . LEU B 1 433 ? 135.541 138.595 156.996 1.00 36.79  ? 433 LEU B CD2 1 
ATOM   7048  N N   . GLU B 1 434 ? 138.211 142.965 156.750 1.00 39.69  ? 434 GLU B N   1 
ATOM   7049  C CA  . GLU B 1 434 ? 139.372 143.521 157.435 1.00 39.69  ? 434 GLU B CA  1 
ATOM   7050  C C   . GLU B 1 434 ? 138.952 144.469 158.553 1.00 39.69  ? 434 GLU B C   1 
ATOM   7051  O O   . GLU B 1 434 ? 139.534 144.446 159.646 1.00 39.69  ? 434 GLU B O   1 
ATOM   7052  C CB  . GLU B 1 434 ? 140.277 144.231 156.431 1.00 39.69  ? 434 GLU B CB  1 
ATOM   7053  C CG  . GLU B 1 434 ? 140.999 143.285 155.488 1.00 39.69  ? 434 GLU B CG  1 
ATOM   7054  C CD  . GLU B 1 434 ? 142.286 142.744 156.065 1.00 39.69  ? 434 GLU B CD  1 
ATOM   7055  O OE1 . GLU B 1 434 ? 142.800 141.741 155.532 1.00 39.69  ? 434 GLU B OE1 1 
ATOM   7056  O OE2 . GLU B 1 434 ? 142.785 143.318 157.054 1.00 39.69  ? 434 GLU B OE2 1 
ATOM   7057  N N   . ASN B 1 435 ? 137.939 145.306 158.304 1.00 37.74  ? 435 ASN B N   1 
ATOM   7058  C CA  . ASN B 1 435 ? 137.471 146.212 159.350 1.00 37.74  ? 435 ASN B CA  1 
ATOM   7059  C C   . ASN B 1 435 ? 136.919 145.443 160.547 1.00 37.74  ? 435 ASN B C   1 
ATOM   7060  O O   . ASN B 1 435 ? 137.194 145.792 161.708 1.00 37.74  ? 435 ASN B O   1 
ATOM   7061  C CB  . ASN B 1 435 ? 136.414 147.158 158.786 1.00 37.74  ? 435 ASN B CB  1 
ATOM   7062  C CG  . ASN B 1 435 ? 137.007 148.233 157.900 1.00 37.74  ? 435 ASN B CG  1 
ATOM   7063  O OD1 . ASN B 1 435 ? 138.216 148.447 157.886 1.00 37.74  ? 435 ASN B OD1 1 
ATOM   7064  N ND2 . ASN B 1 435 ? 136.154 148.912 157.150 1.00 37.74  ? 435 ASN B ND2 1 
ATOM   7065  N N   . GLN B 1 436 ? 136.136 144.391 160.281 1.00 41.81  ? 436 GLN B N   1 
ATOM   7066  C CA  . GLN B 1 436 ? 135.605 143.573 161.368 1.00 41.81  ? 436 GLN B CA  1 
ATOM   7067  C C   . GLN B 1 436 ? 136.730 143.014 162.234 1.00 41.81  ? 436 GLN B C   1 
ATOM   7068  O O   . GLN B 1 436 ? 136.693 143.110 163.472 1.00 41.81  ? 436 GLN B O   1 
ATOM   7069  C CB  . GLN B 1 436 ? 134.754 142.442 160.791 1.00 41.81  ? 436 GLN B CB  1 
ATOM   7070  C CG  . GLN B 1 436 ? 134.219 141.467 161.822 1.00 41.81  ? 436 GLN B CG  1 
ATOM   7071  C CD  . GLN B 1 436 ? 132.924 141.936 162.450 1.00 41.81  ? 436 GLN B CD  1 
ATOM   7072  O OE1 . GLN B 1 436 ? 132.225 142.783 161.900 1.00 41.81  ? 436 GLN B OE1 1 
ATOM   7073  N NE2 . GLN B 1 436 ? 132.600 141.388 163.613 1.00 41.81  ? 436 GLN B NE2 1 
ATOM   7074  N N   . HIS B 1 437 ? 137.757 142.450 161.596 1.00 43.31  ? 437 HIS B N   1 
ATOM   7075  C CA  . HIS B 1 437 ? 138.832 141.845 162.377 1.00 43.31  ? 437 HIS B CA  1 
ATOM   7076  C C   . HIS B 1 437 ? 139.655 142.887 163.130 1.00 43.31  ? 437 HIS B C   1 
ATOM   7077  O O   . HIS B 1 437 ? 140.122 142.612 164.241 1.00 43.31  ? 437 HIS B O   1 
ATOM   7078  C CB  . HIS B 1 437 ? 139.715 140.984 161.480 1.00 43.31  ? 437 HIS B CB  1 
ATOM   7079  C CG  . HIS B 1 437 ? 139.154 139.618 161.234 1.00 43.31  ? 437 HIS B CG  1 
ATOM   7080  N ND1 . HIS B 1 437 ? 139.317 138.576 162.120 1.00 43.31  ? 437 HIS B ND1 1 
ATOM   7081  C CD2 . HIS B 1 437 ? 138.405 139.132 160.216 1.00 43.31  ? 437 HIS B CD2 1 
ATOM   7082  C CE1 . HIS B 1 437 ? 138.704 137.504 161.653 1.00 43.31  ? 437 HIS B CE1 1 
ATOM   7083  N NE2 . HIS B 1 437 ? 138.144 137.814 160.499 1.00 43.31  ? 437 HIS B NE2 1 
ATOM   7084  N N   . THR B 1 438 ? 139.832 144.084 162.564 1.00 44.99  ? 438 THR B N   1 
ATOM   7085  C CA  . THR B 1 438 ? 140.550 145.138 163.281 1.00 44.99  ? 438 THR B CA  1 
ATOM   7086  C C   . THR B 1 438 ? 139.825 145.525 164.568 1.00 44.99  ? 438 THR B C   1 
ATOM   7087  O O   . THR B 1 438 ? 140.439 145.624 165.645 1.00 44.99  ? 438 THR B O   1 
ATOM   7088  C CB  . THR B 1 438 ? 140.721 146.362 162.381 1.00 44.99  ? 438 THR B CB  1 
ATOM   7089  O OG1 . THR B 1 438 ? 141.560 146.029 161.272 1.00 44.99  ? 438 THR B OG1 1 
ATOM   7090  C CG2 . THR B 1 438 ? 141.343 147.516 163.151 1.00 44.99  ? 438 THR B CG2 1 
ATOM   7091  N N   . ILE B 1 439 ? 138.510 145.749 164.471 1.00 47.44  ? 439 ILE B N   1 
ATOM   7092  C CA  . ILE B 1 439 ? 137.738 146.106 165.660 1.00 47.44  ? 439 ILE B CA  1 
ATOM   7093  C C   . ILE B 1 439 ? 137.832 144.999 166.705 1.00 47.44  ? 439 ILE B C   1 
ATOM   7094  O O   . ILE B 1 439 ? 138.052 145.261 167.902 1.00 47.44  ? 439 ILE B O   1 
ATOM   7095  C CB  . ILE B 1 439 ? 136.276 146.405 165.280 1.00 47.44  ? 439 ILE B CB  1 
ATOM   7096  C CG1 . ILE B 1 439 ? 136.207 147.588 164.315 1.00 47.44  ? 439 ILE B CG1 1 
ATOM   7097  C CG2 . ILE B 1 439 ? 135.443 146.674 166.520 1.00 47.44  ? 439 ILE B CG2 1 
ATOM   7098  C CD1 . ILE B 1 439 ? 136.897 148.823 164.824 1.00 47.44  ? 439 ILE B CD1 1 
ATOM   7099  N N   . ASP B 1 440 ? 137.689 143.744 166.264 1.00 50.16  ? 440 ASP B N   1 
ATOM   7100  C CA  . ASP B 1 440 ? 137.753 142.626 167.198 1.00 50.16  ? 440 ASP B CA  1 
ATOM   7101  C C   . ASP B 1 440 ? 139.101 142.565 167.908 1.00 50.16  ? 440 ASP B C   1 
ATOM   7102  O O   . ASP B 1 440 ? 139.157 142.346 169.125 1.00 50.16  ? 440 ASP B O   1 
ATOM   7103  C CB  . ASP B 1 440 ? 137.473 141.315 166.466 1.00 50.16  ? 440 ASP B CB  1 
ATOM   7104  C CG  . ASP B 1 440 ? 135.998 141.100 166.200 1.00 50.16  ? 440 ASP B CG  1 
ATOM   7105  O OD1 . ASP B 1 440 ? 135.188 141.959 166.606 1.00 50.16  ? 440 ASP B OD1 1 
ATOM   7106  O OD2 . ASP B 1 440 ? 135.646 140.073 165.583 1.00 50.16  ? 440 ASP B OD2 1 
ATOM   7107  N N   . LEU B 1 441 ? 140.199 142.759 167.170 1.00 52.26  ? 441 LEU B N   1 
ATOM   7108  C CA  . LEU B 1 441 ? 141.516 142.645 167.790 1.00 52.26  ? 441 LEU B CA  1 
ATOM   7109  C C   . LEU B 1 441 ? 141.753 143.754 168.809 1.00 52.26  ? 441 LEU B C   1 
ATOM   7110  O O   . LEU B 1 441 ? 142.314 143.501 169.884 1.00 52.26  ? 441 LEU B O   1 
ATOM   7111  C CB  . LEU B 1 441 ? 142.617 142.623 166.724 1.00 52.26  ? 441 LEU B CB  1 
ATOM   7112  C CG  . LEU B 1 441 ? 143.202 143.883 166.074 1.00 52.26  ? 441 LEU B CG  1 
ATOM   7113  C CD1 . LEU B 1 441 ? 144.374 144.444 166.866 1.00 52.26  ? 441 LEU B CD1 1 
ATOM   7114  C CD2 . LEU B 1 441 ? 143.639 143.572 164.653 1.00 52.26  ? 441 LEU B CD2 1 
ATOM   7115  N N   . THR B 1 442 ? 141.331 144.987 168.505 1.00 53.92  ? 442 THR B N   1 
ATOM   7116  C CA  . THR B 1 442 ? 141.527 146.058 169.483 1.00 53.92  ? 442 THR B CA  1 
ATOM   7117  C C   . THR B 1 442 ? 140.728 145.798 170.761 1.00 53.92  ? 442 THR B C   1 
ATOM   7118  O O   . THR B 1 442 ? 141.247 145.965 171.882 1.00 53.92  ? 442 THR B O   1 
ATOM   7119  C CB  . THR B 1 442 ? 141.154 147.413 168.878 1.00 53.92  ? 442 THR B CB  1 
ATOM   7120  O OG1 . THR B 1 442 ? 139.922 147.301 168.158 1.00 53.92  ? 442 THR B OG1 1 
ATOM   7121  C CG2 . THR B 1 442 ? 142.246 147.892 167.937 1.00 53.92  ? 442 THR B CG2 1 
ATOM   7122  N N   . ASP B 1 443 ? 139.471 145.362 170.616 1.00 57.15  ? 443 ASP B N   1 
ATOM   7123  C CA  . ASP B 1 443 ? 138.670 145.061 171.800 1.00 57.15  ? 443 ASP B CA  1 
ATOM   7124  C C   . ASP B 1 443 ? 139.295 143.936 172.621 1.00 57.15  ? 443 ASP B C   1 
ATOM   7125  O O   . ASP B 1 443 ? 139.361 144.016 173.859 1.00 57.15  ? 443 ASP B O   1 
ATOM   7126  C CB  . ASP B 1 443 ? 137.243 144.702 171.391 1.00 57.15  ? 443 ASP B CB  1 
ATOM   7127  C CG  . ASP B 1 443 ? 136.438 145.910 170.960 1.00 57.15  ? 443 ASP B CG  1 
ATOM   7128  O OD1 . ASP B 1 443 ? 136.840 147.043 171.295 1.00 57.15  ? 443 ASP B OD1 1 
ATOM   7129  O OD2 . ASP B 1 443 ? 135.401 145.729 170.289 1.00 57.15  ? 443 ASP B OD2 1 
ATOM   7130  N N   . SER B 1 444 ? 139.768 142.883 171.948 1.00 59.45  ? 444 SER B N   1 
ATOM   7131  C CA  . SER B 1 444 ? 140.375 141.763 172.658 1.00 59.45  ? 444 SER B CA  1 
ATOM   7132  C C   . SER B 1 444 ? 141.635 142.192 173.397 1.00 59.45  ? 444 SER B C   1 
ATOM   7133  O O   . SER B 1 444 ? 141.896 141.723 174.509 1.00 59.45  ? 444 SER B O   1 
ATOM   7134  C CB  . SER B 1 444 ? 140.685 140.626 171.685 1.00 59.45  ? 444 SER B CB  1 
ATOM   7135  O OG  . SER B 1 444 ? 141.844 140.908 170.923 1.00 59.45  ? 444 SER B OG  1 
ATOM   7136  N N   . GLU B 1 445 ? 142.435 143.077 172.795 1.00 63.71  ? 445 GLU B N   1 
ATOM   7137  C CA  . GLU B 1 445 ? 143.632 143.568 173.473 1.00 63.71  ? 445 GLU B CA  1 
ATOM   7138  C C   . GLU B 1 445 ? 143.274 144.294 174.766 1.00 63.71  ? 445 GLU B C   1 
ATOM   7139  O O   . GLU B 1 445 ? 143.888 144.059 175.819 1.00 63.71  ? 445 GLU B O   1 
ATOM   7140  C CB  . GLU B 1 445 ? 144.419 144.491 172.542 1.00 63.71  ? 445 GLU B CB  1 
ATOM   7141  C CG  . GLU B 1 445 ? 145.901 144.587 172.858 1.00 63.71  ? 445 GLU B CG  1 
ATOM   7142  C CD  . GLU B 1 445 ? 146.638 143.287 172.611 1.00 63.71  ? 445 GLU B CD  1 
ATOM   7143  O OE1 . GLU B 1 445 ? 146.385 142.649 171.569 1.00 63.71  ? 445 GLU B OE1 1 
ATOM   7144  O OE2 . GLU B 1 445 ? 147.472 142.904 173.458 1.00 63.71  ? 445 GLU B OE2 1 
ATOM   7145  N N   . MET B 1 446 ? 142.276 145.183 174.706 1.00 65.23  ? 446 MET B N   1 
ATOM   7146  C CA  . MET B 1 446 ? 141.881 145.898 175.920 1.00 65.23  ? 446 MET B CA  1 
ATOM   7147  C C   . MET B 1 446 ? 141.412 144.927 177.002 1.00 65.23  ? 446 MET B C   1 
ATOM   7148  O O   . MET B 1 446 ? 141.807 145.033 178.176 1.00 65.23  ? 446 MET B O   1 
ATOM   7149  C CB  . MET B 1 446 ? 140.788 146.920 175.601 1.00 65.23  ? 446 MET B CB  1 
ATOM   7150  C CG  . MET B 1 446 ? 140.249 147.655 176.820 1.00 65.23  ? 446 MET B CG  1 
ATOM   7151  S SD  . MET B 1 446 ? 141.134 149.184 177.190 1.00 65.23  ? 446 MET B SD  1 
ATOM   7152  C CE  . MET B 1 446 ? 142.035 148.723 178.665 1.00 65.23  ? 446 MET B CE  1 
ATOM   7153  N N   . ASN B 1 447 ? 140.578 143.956 176.616 1.00 66.15  ? 447 ASN B N   1 
ATOM   7154  C CA  . ASN B 1 447 ? 140.062 143.000 177.593 1.00 66.15  ? 447 ASN B CA  1 
ATOM   7155  C C   . ASN B 1 447 ? 141.180 142.155 178.194 1.00 66.15  ? 447 ASN B C   1 
ATOM   7156  O O   . ASN B 1 447 ? 141.164 141.852 179.393 1.00 66.15  ? 447 ASN B O   1 
ATOM   7157  C CB  . ASN B 1 447 ? 139.004 142.110 176.947 1.00 66.15  ? 447 ASN B CB  1 
ATOM   7158  C CG  . ASN B 1 447 ? 137.655 142.785 176.867 1.00 66.15  ? 447 ASN B CG  1 
ATOM   7159  O OD1 . ASN B 1 447 ? 137.145 143.295 177.863 1.00 66.15  ? 447 ASN B OD1 1 
ATOM   7160  N ND2 . ASN B 1 447 ? 137.070 142.800 175.677 1.00 66.15  ? 447 ASN B ND2 1 
ATOM   7161  N N   . LYS B 1 448 ? 142.154 141.756 177.374 1.00 68.16  ? 448 LYS B N   1 
ATOM   7162  C CA  . LYS B 1 448 ? 143.271 140.964 177.876 1.00 68.16  ? 448 LYS B CA  1 
ATOM   7163  C C   . LYS B 1 448 ? 144.086 141.745 178.895 1.00 68.16  ? 448 LYS B C   1 
ATOM   7164  O O   . LYS B 1 448 ? 144.502 141.192 179.921 1.00 68.16  ? 448 LYS B O   1 
ATOM   7165  C CB  . LYS B 1 448 ? 144.159 140.514 176.718 1.00 68.16  ? 448 LYS B CB  1 
ATOM   7166  C CG  . LYS B 1 448 ? 143.820 139.139 176.171 1.00 68.16  ? 448 LYS B CG  1 
ATOM   7167  C CD  . LYS B 1 448 ? 144.507 138.879 174.837 1.00 68.16  ? 448 LYS B CD  1 
ATOM   7168  C CE  . LYS B 1 448 ? 145.864 139.564 174.759 1.00 68.16  ? 448 LYS B CE  1 
ATOM   7169  N NZ  . LYS B 1 448 ? 146.188 140.013 173.376 1.00 68.16  ? 448 LYS B NZ  1 
ATOM   7170  N N   . LEU B 1 449 ? 144.340 143.029 178.626 1.00 70.91  ? 449 LEU B N   1 
ATOM   7171  C CA  . LEU B 1 449 ? 145.066 143.834 179.604 1.00 70.91  ? 449 LEU B CA  1 
ATOM   7172  C C   . LEU B 1 449 ? 144.301 143.922 180.920 1.00 70.91  ? 449 LEU B C   1 
ATOM   7173  O O   . LEU B 1 449 ? 144.888 143.776 182.005 1.00 70.91  ? 449 LEU B O   1 
ATOM   7174  C CB  . LEU B 1 449 ? 145.340 145.231 179.049 1.00 70.91  ? 449 LEU B CB  1 
ATOM   7175  C CG  . LEU B 1 449 ? 146.124 146.157 179.980 1.00 70.91  ? 449 LEU B CG  1 
ATOM   7176  C CD1 . LEU B 1 449 ? 147.456 145.532 180.371 1.00 70.91  ? 449 LEU B CD1 1 
ATOM   7177  C CD2 . LEU B 1 449 ? 146.332 147.517 179.341 1.00 70.91  ? 449 LEU B CD2 1 
ATOM   7178  N N   . PHE B 1 450 ? 142.983 144.141 180.847 1.00 75.32  ? 450 PHE B N   1 
ATOM   7179  C CA  . PHE B 1 450 ? 142.197 144.202 182.077 1.00 75.32  ? 450 PHE B CA  1 
ATOM   7180  C C   . PHE B 1 450 ? 142.259 142.884 182.845 1.00 75.32  ? 450 PHE B C   1 
ATOM   7181  O O   . PHE B 1 450 ? 142.393 142.878 184.076 1.00 75.32  ? 450 PHE B O   1 
ATOM   7182  C CB  . PHE B 1 450 ? 140.746 144.566 181.772 1.00 75.32  ? 450 PHE B CB  1 
ATOM   7183  C CG  . PHE B 1 450 ? 139.901 144.746 183.000 1.00 75.32  ? 450 PHE B CG  1 
ATOM   7184  C CD1 . PHE B 1 450 ? 139.946 145.926 183.721 1.00 75.32  ? 450 PHE B CD1 1 
ATOM   7185  C CD2 . PHE B 1 450 ? 139.069 143.732 183.441 1.00 75.32  ? 450 PHE B CD2 1 
ATOM   7186  C CE1 . PHE B 1 450 ? 139.174 146.095 184.852 1.00 75.32  ? 450 PHE B CE1 1 
ATOM   7187  C CE2 . PHE B 1 450 ? 138.295 143.894 184.571 1.00 75.32  ? 450 PHE B CE2 1 
ATOM   7188  C CZ  . PHE B 1 450 ? 138.347 145.077 185.277 1.00 75.32  ? 450 PHE B CZ  1 
ATOM   7189  N N   . GLU B 1 451 ? 142.164 141.757 182.136 1.00 76.90  ? 451 GLU B N   1 
ATOM   7190  C CA  . GLU B 1 451 ? 142.189 140.460 182.809 1.00 76.90  ? 451 GLU B CA  1 
ATOM   7191  C C   . GLU B 1 451 ? 143.548 140.178 183.439 1.00 76.90  ? 451 GLU B C   1 
ATOM   7192  O O   . GLU B 1 451 ? 143.623 139.590 184.523 1.00 76.90  ? 451 GLU B O   1 
ATOM   7193  C CB  . GLU B 1 451 ? 141.809 139.348 181.833 1.00 76.90  ? 451 GLU B CB  1 
ATOM   7194  C CG  . GLU B 1 451 ? 140.797 138.363 182.396 1.00 76.90  ? 451 GLU B CG  1 
ATOM   7195  C CD  . GLU B 1 451 ? 139.699 139.033 183.207 1.00 76.90  ? 451 GLU B CD  1 
ATOM   7196  O OE1 . GLU B 1 451 ? 139.401 138.548 184.318 1.00 76.90  ? 451 GLU B OE1 1 
ATOM   7197  O OE2 . GLU B 1 451 ? 139.113 140.026 182.724 1.00 76.90  ? 451 GLU B OE2 1 
ATOM   7198  N N   . LYS B 1 452 ? 144.634 140.567 182.769 1.00 78.28  ? 452 LYS B N   1 
ATOM   7199  C CA  . LYS B 1 452 ? 145.960 140.412 183.359 1.00 78.28  ? 452 LYS B CA  1 
ATOM   7200  C C   . LYS B 1 452 ? 146.080 141.219 184.646 1.00 78.28  ? 452 LYS B C   1 
ATOM   7201  O O   . LYS B 1 452 ? 146.583 140.724 185.668 1.00 78.28  ? 452 LYS B O   1 
ATOM   7202  C CB  . LYS B 1 452 ? 147.026 140.838 182.352 1.00 78.28  ? 452 LYS B CB  1 
ATOM   7203  C CG  . LYS B 1 452 ? 148.400 140.251 182.597 1.00 78.28  ? 452 LYS B CG  1 
ATOM   7204  C CD  . LYS B 1 452 ? 149.473 141.100 181.939 1.00 78.28  ? 452 LYS B CD  1 
ATOM   7205  C CE  . LYS B 1 452 ? 150.759 141.090 182.747 1.00 78.28  ? 452 LYS B CE  1 
ATOM   7206  N NZ  . LYS B 1 452 ? 151.300 142.458 182.952 1.00 78.28  ? 452 LYS B NZ  1 
ATOM   7207  N N   . THR B 1 453 ? 145.603 142.467 184.619 1.00 79.74  ? 453 THR B N   1 
ATOM   7208  C CA  . THR B 1 453 ? 145.635 143.285 185.828 1.00 79.74  ? 453 THR B CA  1 
ATOM   7209  C C   . THR B 1 453 ? 144.811 142.648 186.941 1.00 79.74  ? 453 THR B C   1 
ATOM   7210  O O   . THR B 1 453 ? 145.222 142.649 188.107 1.00 79.74  ? 453 THR B O   1 
ATOM   7211  C CB  . THR B 1 453 ? 145.136 144.697 185.524 1.00 79.74  ? 453 THR B CB  1 
ATOM   7212  O OG1 . THR B 1 453 ? 146.092 145.371 184.698 1.00 79.74  ? 453 THR B OG1 1 
ATOM   7213  C CG2 . THR B 1 453 ? 144.950 145.487 186.809 1.00 79.74  ? 453 THR B CG2 1 
ATOM   7214  N N   . ARG B 1 454 ? 143.649 142.084 186.598 1.00 81.72  ? 454 ARG B N   1 
ATOM   7215  C CA  . ARG B 1 454 ? 142.847 141.382 187.598 1.00 81.72  ? 454 ARG B CA  1 
ATOM   7216  C C   . ARG B 1 454 ? 143.602 140.191 188.174 1.00 81.72  ? 454 ARG B C   1 
ATOM   7217  O O   . ARG B 1 454 ? 143.542 139.933 189.382 1.00 81.72  ? 454 ARG B O   1 
ATOM   7218  C CB  . ARG B 1 454 ? 141.520 140.924 186.994 1.00 81.72  ? 454 ARG B CB  1 
ATOM   7219  C CG  . ARG B 1 454 ? 140.726 139.995 187.902 1.00 81.72  ? 454 ARG B CG  1 
ATOM   7220  C CD  . ARG B 1 454 ? 139.233 140.272 187.835 1.00 81.72  ? 454 ARG B CD  1 
ATOM   7221  N NE  . ARG B 1 454 ? 138.705 140.129 186.484 1.00 81.72  ? 454 ARG B NE  1 
ATOM   7222  C CZ  . ARG B 1 454 ? 137.498 140.527 186.106 1.00 81.72  ? 454 ARG B CZ  1 
ATOM   7223  N NH1 . ARG B 1 454 ? 136.662 141.100 186.955 1.00 81.72  ? 454 ARG B NH1 1 
ATOM   7224  N NH2 . ARG B 1 454 ? 137.121 140.346 184.843 1.00 81.72  ? 454 ARG B NH2 1 
ATOM   7225  N N   . ARG B 1 455 ? 144.313 139.448 187.324 1.00 84.41  ? 455 ARG B N   1 
ATOM   7226  C CA  . ARG B 1 455 ? 145.083 138.305 187.805 1.00 84.41  ? 455 ARG B CA  1 
ATOM   7227  C C   . ARG B 1 455 ? 146.154 138.737 188.797 1.00 84.41  ? 455 ARG B C   1 
ATOM   7228  O O   . ARG B 1 455 ? 146.403 138.044 189.791 1.00 84.41  ? 455 ARG B O   1 
ATOM   7229  C CB  . ARG B 1 455 ? 145.723 137.557 186.636 1.00 84.41  ? 455 ARG B CB  1 
ATOM   7230  C CG  . ARG B 1 455 ? 144.773 136.670 185.861 1.00 84.41  ? 455 ARG B CG  1 
ATOM   7231  C CD  . ARG B 1 455 ? 145.535 135.674 185.007 1.00 84.41  ? 455 ARG B CD  1 
ATOM   7232  N NE  . ARG B 1 455 ? 145.111 135.713 183.614 1.00 84.41  ? 455 ARG B NE  1 
ATOM   7233  C CZ  . ARG B 1 455 ? 145.909 136.004 182.596 1.00 84.41  ? 455 ARG B CZ  1 
ATOM   7234  N NH1 . ARG B 1 455 ? 147.194 136.265 182.777 1.00 84.41  ? 455 ARG B NH1 1 
ATOM   7235  N NH2 . ARG B 1 455 ? 145.407 136.031 181.365 1.00 84.41  ? 455 ARG B NH2 1 
ATOM   7236  N N   . GLN B 1 456 ? 146.813 139.870 188.537 1.00 87.60  ? 456 GLN B N   1 
ATOM   7237  C CA  . GLN B 1 456 ? 147.857 140.320 189.457 1.00 87.60  ? 456 GLN B CA  1 
ATOM   7238  C C   . GLN B 1 456 ? 147.296 140.607 190.847 1.00 87.60  ? 456 GLN B C   1 
ATOM   7239  O O   . GLN B 1 456 ? 147.897 140.223 191.856 1.00 87.60  ? 456 GLN B O   1 
ATOM   7240  C CB  . GLN B 1 456 ? 148.566 141.552 188.900 1.00 87.60  ? 456 GLN B CB  1 
ATOM   7241  C CG  . GLN B 1 456 ? 149.542 141.243 187.786 1.00 87.60  ? 456 GLN B CG  1 
ATOM   7242  C CD  . GLN B 1 456 ? 150.496 142.387 187.520 1.00 87.60  ? 456 GLN B CD  1 
ATOM   7243  O OE1 . GLN B 1 456 ? 150.662 142.821 186.382 1.00 87.60  ? 456 GLN B OE1 1 
ATOM   7244  N NE2 . GLN B 1 456 ? 151.133 142.881 188.574 1.00 87.60  ? 456 GLN B NE2 1 
ATOM   7245  N N   . LEU B 1 457 ? 146.148 141.279 190.923 1.00 89.85  ? 457 LEU B N   1 
ATOM   7246  C CA  . LEU B 1 457 ? 145.488 141.548 192.202 1.00 89.85  ? 457 LEU B CA  1 
ATOM   7247  C C   . LEU B 1 457 ? 144.585 140.363 192.519 1.00 89.85  ? 457 LEU B C   1 
ATOM   7248  O O   . LEU B 1 457 ? 143.418 140.319 192.129 1.00 89.85  ? 457 LEU B O   1 
ATOM   7249  C CB  . LEU B 1 457 ? 144.703 142.852 192.144 1.00 89.85  ? 457 LEU B CB  1 
ATOM   7250  C CG  . LEU B 1 457 ? 145.490 144.126 191.827 1.00 89.85  ? 457 LEU B CG  1 
ATOM   7251  C CD1 . LEU B 1 457 ? 144.569 145.185 191.250 1.00 89.85  ? 457 LEU B CD1 1 
ATOM   7252  C CD2 . LEU B 1 457 ? 146.197 144.644 193.066 1.00 89.85  ? 457 LEU B CD2 1 
ATOM   7253  N N   . ARG B 1 458 ? 145.130 139.393 193.256 1.00 93.90  ? 458 ARG B N   1 
ATOM   7254  C CA  . ARG B 1 458 ? 144.442 138.118 193.434 1.00 93.90  ? 458 ARG B CA  1 
ATOM   7255  C C   . ARG B 1 458 ? 143.233 138.261 194.352 1.00 93.90  ? 458 ARG B C   1 
ATOM   7256  O O   . ARG B 1 458 ? 142.091 138.046 193.932 1.00 93.90  ? 458 ARG B O   1 
ATOM   7257  C CB  . ARG B 1 458 ? 145.427 137.080 193.971 1.00 93.90  ? 458 ARG B CB  1 
ATOM   7258  C CG  . ARG B 1 458 ? 146.447 136.651 192.933 1.00 93.90  ? 458 ARG B CG  1 
ATOM   7259  C CD  . ARG B 1 458 ? 147.390 135.576 193.441 1.00 93.90  ? 458 ARG B CD  1 
ATOM   7260  N NE  . ARG B 1 458 ? 146.735 134.590 194.291 1.00 93.90  ? 458 ARG B NE  1 
ATOM   7261  C CZ  . ARG B 1 458 ? 147.346 133.532 194.805 1.00 93.90  ? 458 ARG B CZ  1 
ATOM   7262  N NH1 . ARG B 1 458 ? 148.625 133.291 194.568 1.00 93.90  ? 458 ARG B NH1 1 
ATOM   7263  N NH2 . ARG B 1 458 ? 146.658 132.696 195.575 1.00 93.90  ? 458 ARG B NH2 1 
ATOM   7264  N N   . GLU B 1 459 ? 143.463 138.635 195.612 1.00 97.00  ? 459 GLU B N   1 
ATOM   7265  C CA  . GLU B 1 459 ? 142.377 138.846 196.561 1.00 97.00  ? 459 GLU B CA  1 
ATOM   7266  C C   . GLU B 1 459 ? 142.465 140.198 197.256 1.00 97.00  ? 459 GLU B C   1 
ATOM   7267  O O   . GLU B 1 459 ? 141.729 140.431 198.222 1.00 97.00  ? 459 GLU B O   1 
ATOM   7268  C CB  . GLU B 1 459 ? 142.347 137.731 197.613 1.00 97.00  ? 459 GLU B CB  1 
ATOM   7269  C CG  . GLU B 1 459 ? 141.993 136.361 197.063 1.00 97.00  ? 459 GLU B CG  1 
ATOM   7270  C CD  . GLU B 1 459 ? 140.512 136.210 196.777 1.00 97.00  ? 459 GLU B CD  1 
ATOM   7271  O OE1 . GLU B 1 459 ? 139.723 137.055 197.250 1.00 97.00  ? 459 GLU B OE1 1 
ATOM   7272  O OE2 . GLU B 1 459 ? 140.138 135.247 196.076 1.00 97.00  ? 459 GLU B OE2 1 
ATOM   7273  N N   . ASN B 1 460 ? 143.334 141.091 196.795 1.00 97.12  ? 460 ASN B N   1 
ATOM   7274  C CA  . ASN B 1 460 ? 143.589 142.346 197.485 1.00 97.12  ? 460 ASN B CA  1 
ATOM   7275  C C   . ASN B 1 460 ? 142.732 143.500 196.979 1.00 97.12  ? 460 ASN B C   1 
ATOM   7276  O O   . ASN B 1 460 ? 142.820 144.601 197.531 1.00 97.12  ? 460 ASN B O   1 
ATOM   7277  C CB  . ASN B 1 460 ? 145.069 142.716 197.350 1.00 97.12  ? 460 ASN B CB  1 
ATOM   7278  C CG  . ASN B 1 460 ? 145.955 141.927 198.290 1.00 97.12  ? 460 ASN B CG  1 
ATOM   7279  O OD1 . ASN B 1 460 ? 147.014 141.443 197.899 1.00 97.12  ? 460 ASN B OD1 1 
ATOM   7280  N ND2 . ASN B 1 460 ? 145.515 141.770 199.529 1.00 97.12  ? 460 ASN B ND2 1 
ATOM   7281  N N   . ALA B 1 461 ? 141.902 143.282 195.961 1.00 95.48  ? 461 ALA B N   1 
ATOM   7282  C CA  . ALA B 1 461 ? 141.183 144.370 195.313 1.00 95.48  ? 461 ALA B CA  1 
ATOM   7283  C C   . ALA B 1 461 ? 139.811 143.895 194.859 1.00 95.48  ? 461 ALA B C   1 
ATOM   7284  O O   . ALA B 1 461 ? 139.552 142.696 194.740 1.00 95.48  ? 461 ALA B O   1 
ATOM   7285  C CB  . ALA B 1 461 ? 141.967 144.927 194.118 1.00 95.48  ? 461 ALA B CB  1 
ATOM   7286  N N   . GLU B 1 462 ? 138.931 144.863 194.599 1.00 94.96  ? 462 GLU B N   1 
ATOM   7287  C CA  . GLU B 1 462 ? 137.573 144.590 194.147 1.00 94.96  ? 462 GLU B CA  1 
ATOM   7288  C C   . GLU B 1 462 ? 137.265 145.381 192.883 1.00 94.96  ? 462 GLU B C   1 
ATOM   7289  O O   . GLU B 1 462 ? 137.617 146.559 192.775 1.00 94.96  ? 462 GLU B O   1 
ATOM   7290  C CB  . GLU B 1 462 ? 136.547 144.930 195.231 1.00 94.96  ? 462 GLU B CB  1 
ATOM   7291  C CG  . GLU B 1 462 ? 135.172 144.339 194.983 1.00 94.96  ? 462 GLU B CG  1 
ATOM   7292  C CD  . GLU B 1 462 ? 134.409 144.065 196.265 1.00 94.96  ? 462 GLU B CD  1 
ATOM   7293  O OE1 . GLU B 1 462 ? 135.054 143.881 197.319 1.00 94.96  ? 462 GLU B OE1 1 
ATOM   7294  O OE2 . GLU B 1 462 ? 133.162 144.043 196.220 1.00 94.96  ? 462 GLU B OE2 1 
ATOM   7295  N N   . ASP B 1 463 ? 136.594 144.730 191.935 1.00 90.18  ? 463 ASP B N   1 
ATOM   7296  C CA  . ASP B 1 463 ? 136.236 145.359 190.669 1.00 90.18  ? 463 ASP B CA  1 
ATOM   7297  C C   . ASP B 1 463 ? 134.938 146.143 190.826 1.00 90.18  ? 463 ASP B C   1 
ATOM   7298  O O   . ASP B 1 463 ? 133.910 145.579 191.214 1.00 90.18  ? 463 ASP B O   1 
ATOM   7299  C CB  . ASP B 1 463 ? 136.094 144.305 189.574 1.00 90.18  ? 463 ASP B CB  1 
ATOM   7300  C CG  . ASP B 1 463 ? 135.482 144.865 188.304 1.00 90.18  ? 463 ASP B CG  1 
ATOM   7301  N N   . MET B 1 464 ? 134.982 147.441 190.520 1.00 89.56  ? 464 MET B N   1 
ATOM   7302  C CA  . MET B 1 464 ? 133.785 148.269 190.600 1.00 89.56  ? 464 MET B CA  1 
ATOM   7303  C C   . MET B 1 464 ? 132.804 148.010 189.466 1.00 89.56  ? 464 MET B C   1 
ATOM   7304  O O   . MET B 1 464 ? 131.674 148.506 189.527 1.00 89.56  ? 464 MET B O   1 
ATOM   7305  C CB  . MET B 1 464 ? 134.154 149.752 190.614 1.00 89.56  ? 464 MET B CB  1 
ATOM   7306  C CG  . MET B 1 464 ? 134.558 150.270 191.977 1.00 89.56  ? 464 MET B CG  1 
ATOM   7307  S SD  . MET B 1 464 ? 136.337 150.471 192.124 1.00 89.56  ? 464 MET B SD  1 
ATOM   7308  C CE  . MET B 1 464 ? 136.544 152.097 191.408 1.00 89.56  ? 464 MET B CE  1 
ATOM   7309  N N   . GLY B 1 465 ? 133.200 147.263 188.439 1.00 87.14  ? 465 GLY B N   1 
ATOM   7310  C CA  . GLY B 1 465 ? 132.319 146.967 187.331 1.00 87.14  ? 465 GLY B CA  1 
ATOM   7311  C C   . GLY B 1 465 ? 132.276 148.013 186.239 1.00 87.14  ? 465 GLY B C   1 
ATOM   7312  O O   . GLY B 1 465 ? 131.517 147.844 185.276 1.00 87.14  ? 465 GLY B O   1 
ATOM   7313  N N   . ASN B 1 466 ? 133.055 149.087 186.357 1.00 84.59  ? 466 ASN B N   1 
ATOM   7314  C CA  . ASN B 1 466 ? 133.181 150.095 185.312 1.00 84.59  ? 466 ASN B CA  1 
ATOM   7315  C C   . ASN B 1 466 ? 134.588 150.119 184.723 1.00 84.59  ? 466 ASN B C   1 
ATOM   7316  O O   . ASN B 1 466 ? 135.046 151.152 184.234 1.00 84.59  ? 466 ASN B O   1 
ATOM   7317  C CB  . ASN B 1 466 ? 132.802 151.475 185.847 1.00 84.59  ? 466 ASN B CB  1 
ATOM   7318  C CG  . ASN B 1 466 ? 133.638 151.890 187.041 1.00 84.59  ? 466 ASN B CG  1 
ATOM   7319  O OD1 . ASN B 1 466 ? 134.489 151.136 187.510 1.00 84.59  ? 466 ASN B OD1 1 
ATOM   7320  N ND2 . ASN B 1 466 ? 133.398 153.096 187.539 1.00 84.59  ? 466 ASN B ND2 1 
ATOM   7321  N N   . GLY B 1 467 ? 135.283 148.986 184.772 1.00 81.93  ? 467 GLY B N   1 
ATOM   7322  C CA  . GLY B 1 467 ? 136.659 148.917 184.327 1.00 81.93  ? 467 GLY B CA  1 
ATOM   7323  C C   . GLY B 1 467 ? 137.679 149.392 185.333 1.00 81.93  ? 467 GLY B C   1 
ATOM   7324  O O   . GLY B 1 467 ? 138.836 149.613 184.960 1.00 81.93  ? 467 GLY B O   1 
ATOM   7325  N N   . CYS B 1 468 ? 137.296 149.547 186.599 1.00 85.01  ? 468 CYS B N   1 
ATOM   7326  C CA  . CYS B 1 468 ? 138.163 150.112 187.621 1.00 85.01  ? 468 CYS B CA  1 
ATOM   7327  C C   . CYS B 1 468 ? 138.235 149.169 188.813 1.00 85.01  ? 468 CYS B C   1 
ATOM   7328  O O   . CYS B 1 468 ? 137.214 148.631 189.250 1.00 85.01  ? 468 CYS B O   1 
ATOM   7329  C CB  . CYS B 1 468 ? 137.642 151.476 188.080 1.00 85.01  ? 468 CYS B CB  1 
ATOM   7330  S SG  . CYS B 1 468 ? 137.888 152.824 186.911 1.00 85.01  ? 468 CYS B SG  1 
ATOM   7331  N N   . PHE B 1 469 ? 139.442 148.976 189.340 1.00 86.04  ? 469 PHE B N   1 
ATOM   7332  C CA  . PHE B 1 469 ? 139.678 148.232 190.565 1.00 86.04  ? 469 PHE B CA  1 
ATOM   7333  C C   . PHE B 1 469 ? 139.870 149.207 191.718 1.00 86.04  ? 469 PHE B C   1 
ATOM   7334  O O   . PHE B 1 469 ? 140.411 150.302 191.540 1.00 86.04  ? 469 PHE B O   1 
ATOM   7335  C CB  . PHE B 1 469 ? 140.928 147.354 190.446 1.00 86.04  ? 469 PHE B CB  1 
ATOM   7336  C CG  . PHE B 1 469 ? 140.778 146.201 189.505 1.00 86.04  ? 469 PHE B CG  1 
ATOM   7337  C CD1 . PHE B 1 469 ? 139.957 145.135 189.818 1.00 86.04  ? 469 PHE B CD1 1 
ATOM   7338  C CD2 . PHE B 1 469 ? 141.462 146.185 188.302 1.00 86.04  ? 469 PHE B CD2 1 
ATOM   7339  C CE1 . PHE B 1 469 ? 139.822 144.075 188.951 1.00 86.04  ? 469 PHE B CE1 1 
ATOM   7340  C CE2 . PHE B 1 469 ? 141.331 145.128 187.432 1.00 86.04  ? 469 PHE B CE2 1 
ATOM   7341  C CZ  . PHE B 1 469 ? 140.508 144.073 187.756 1.00 86.04  ? 469 PHE B CZ  1 
ATOM   7342  N N   . LYS B 1 470 ? 139.428 148.808 192.906 1.00 93.06  ? 470 LYS B N   1 
ATOM   7343  C CA  . LYS B 1 470 ? 139.752 149.535 194.124 1.00 93.06  ? 470 LYS B CA  1 
ATOM   7344  C C   . LYS B 1 470 ? 140.506 148.599 195.058 1.00 93.06  ? 470 LYS B C   1 
ATOM   7345  O O   . LYS B 1 470 ? 140.082 147.460 195.289 1.00 93.06  ? 470 LYS B O   1 
ATOM   7346  C CB  . LYS B 1 470 ? 138.498 150.134 194.779 1.00 93.06  ? 470 LYS B CB  1 
ATOM   7347  C CG  . LYS B 1 470 ? 137.633 149.221 195.620 1.00 93.06  ? 470 LYS B CG  1 
ATOM   7348  C CD  . LYS B 1 470 ? 137.610 149.712 197.060 1.00 93.06  ? 470 LYS B CD  1 
ATOM   7349  C CE  . LYS B 1 470 ? 136.879 148.749 197.972 1.00 93.06  ? 470 LYS B CE  1 
ATOM   7350  N NZ  . LYS B 1 470 ? 136.812 149.246 199.377 1.00 93.06  ? 470 LYS B NZ  1 
ATOM   7351  N N   . ILE B 1 471 ? 141.647 149.075 195.547 1.00 95.31  ? 471 ILE B N   1 
ATOM   7352  C CA  . ILE B 1 471 ? 142.573 148.294 196.355 1.00 95.31  ? 471 ILE B CA  1 
ATOM   7353  C C   . ILE B 1 471 ? 142.372 148.680 197.812 1.00 95.31  ? 471 ILE B C   1 
ATOM   7354  O O   . ILE B 1 471 ? 142.492 149.858 198.174 1.00 95.31  ? 471 ILE B O   1 
ATOM   7355  C CB  . ILE B 1 471 ? 144.026 148.537 195.914 1.00 95.31  ? 471 ILE B CB  1 
ATOM   7356  C CG1 . ILE B 1 471 ? 144.108 148.606 194.387 1.00 95.31  ? 471 ILE B CG1 1 
ATOM   7357  C CG2 . ILE B 1 471 ? 144.940 147.450 196.454 1.00 95.31  ? 471 ILE B CG2 1 
ATOM   7358  C CD1 . ILE B 1 471 ? 145.513 148.723 193.849 1.00 95.31  ? 471 ILE B CD1 1 
ATOM   7359  N N   . TYR B 1 472 ? 142.070 147.686 198.647 1.00 98.68  ? 472 TYR B N   1 
ATOM   7360  C CA  . TYR B 1 472 ? 141.698 147.924 200.035 1.00 98.68  ? 472 TYR B CA  1 
ATOM   7361  C C   . TYR B 1 472 ? 142.864 148.394 200.893 1.00 98.68  ? 472 TYR B C   1 
ATOM   7362  O O   . TYR B 1 472 ? 142.632 149.052 201.912 1.00 98.68  ? 472 TYR B O   1 
ATOM   7363  C CB  . TYR B 1 472 ? 141.102 146.648 200.629 1.00 98.68  ? 472 TYR B CB  1 
ATOM   7364  C CG  . TYR B 1 472 ? 139.723 146.312 200.104 1.00 98.68  ? 472 TYR B CG  1 
ATOM   7365  C CD1 . TYR B 1 472 ? 139.558 145.736 198.851 1.00 98.68  ? 472 TYR B CD1 1 
ATOM   7366  C CD2 . TYR B 1 472 ? 138.590 146.567 200.862 1.00 98.68  ? 472 TYR B CD2 1 
ATOM   7367  C CE1 . TYR B 1 472 ? 138.303 145.427 198.367 1.00 98.68  ? 472 TYR B CE1 1 
ATOM   7368  C CE2 . TYR B 1 472 ? 137.331 146.259 200.387 1.00 98.68  ? 472 TYR B CE2 1 
ATOM   7369  C CZ  . TYR B 1 472 ? 137.194 145.686 199.141 1.00 98.68  ? 472 TYR B CZ  1 
ATOM   7370  O OH  . TYR B 1 472 ? 135.940 145.382 198.665 1.00 98.68  ? 472 TYR B OH  1 
ATOM   7371  N N   . HIS B 1 473 ? 144.095 148.084 200.510 1.00 98.28  ? 473 HIS B N   1 
ATOM   7372  C CA  . HIS B 1 473 ? 145.283 148.416 201.280 1.00 98.28  ? 473 HIS B CA  1 
ATOM   7373  C C   . HIS B 1 473 ? 145.855 149.751 200.810 1.00 98.28  ? 473 HIS B C   1 
ATOM   7374  O O   . HIS B 1 473 ? 145.350 150.380 199.876 1.00 98.28  ? 473 HIS B O   1 
ATOM   7375  C CB  . HIS B 1 473 ? 146.301 147.273 201.182 1.00 98.28  ? 473 HIS B CB  1 
ATOM   7376  C CG  . HIS B 1 473 ? 147.028 147.198 199.872 1.00 98.28  ? 473 HIS B CG  1 
ATOM   7377  N ND1 . HIS B 1 473 ? 147.097 146.036 199.135 1.00 98.28  ? 473 HIS B ND1 1 
ATOM   7378  C CD2 . HIS B 1 473 ? 147.763 148.113 199.195 1.00 98.28  ? 473 HIS B CD2 1 
ATOM   7379  C CE1 . HIS B 1 473 ? 147.814 146.247 198.046 1.00 98.28  ? 473 HIS B CE1 1 
ATOM   7380  N NE2 . HIS B 1 473 ? 148.228 147.500 198.058 1.00 98.28  ? 473 HIS B NE2 1 
ATOM   7381  N N   . LYS B 1 474 ? 146.927 150.181 201.471 1.00 98.37  ? 474 LYS B N   1 
ATOM   7382  C CA  . LYS B 1 474 ? 147.598 151.429 201.119 1.00 98.37  ? 474 LYS B CA  1 
ATOM   7383  C C   . LYS B 1 474 ? 148.585 151.143 199.995 1.00 98.37  ? 474 LYS B C   1 
ATOM   7384  O O   . LYS B 1 474 ? 149.654 150.571 200.217 1.00 98.37  ? 474 LYS B O   1 
ATOM   7385  C CB  . LYS B 1 474 ? 148.294 152.032 202.334 1.00 98.37  ? 474 LYS B CB  1 
ATOM   7386  C CG  . LYS B 1 474 ? 148.381 153.547 202.298 1.00 98.37  ? 474 LYS B CG  1 
ATOM   7387  C CD  . LYS B 1 474 ? 148.177 154.146 203.679 1.00 98.37  ? 474 LYS B CD  1 
ATOM   7388  C CE  . LYS B 1 474 ? 146.698 154.276 204.012 1.00 98.37  ? 474 LYS B CE  1 
ATOM   7389  N NZ  . LYS B 1 474 ? 146.093 155.500 203.417 1.00 98.37  ? 474 LYS B NZ  1 
ATOM   7390  N N   . CYS B 1 475 ? 148.221 151.543 198.782 1.00 97.49  ? 475 CYS B N   1 
ATOM   7391  C CA  . CYS B 1 475 ? 149.016 151.311 197.580 1.00 97.49  ? 475 CYS B CA  1 
ATOM   7392  C C   . CYS B 1 475 ? 149.480 152.676 197.078 1.00 97.49  ? 475 CYS B C   1 
ATOM   7393  O O   . CYS B 1 475 ? 148.706 153.419 196.468 1.00 97.49  ? 475 CYS B O   1 
ATOM   7394  C CB  . CYS B 1 475 ? 148.192 150.559 196.537 1.00 97.49  ? 475 CYS B CB  1 
ATOM   7395  S SG  . CYS B 1 475 ? 149.082 149.785 195.151 1.00 97.49  ? 475 CYS B SG  1 
ATOM   7396  N N   . ASP B 1 476 ? 150.741 153.005 197.344 1.00 96.89  ? 476 ASP B N   1 
ATOM   7397  C CA  . ASP B 1 476 ? 151.293 154.307 197.005 1.00 96.89  ? 476 ASP B CA  1 
ATOM   7398  C C   . ASP B 1 476 ? 151.809 154.294 195.566 1.00 96.89  ? 476 ASP B C   1 
ATOM   7399  O O   . ASP B 1 476 ? 151.537 153.371 194.795 1.00 96.89  ? 476 ASP B O   1 
ATOM   7400  C CB  . ASP B 1 476 ? 152.381 154.696 198.003 1.00 96.89  ? 476 ASP B CB  1 
ATOM   7401  C CG  . ASP B 1 476 ? 153.617 153.834 197.881 1.00 96.89  ? 476 ASP B CG  1 
ATOM   7402  O OD1 . ASP B 1 476 ? 153.485 152.594 197.954 1.00 96.89  ? 476 ASP B OD1 1 
ATOM   7403  O OD2 . ASP B 1 476 ? 154.719 154.395 197.711 1.00 96.89  ? 476 ASP B OD2 1 
ATOM   7404  N N   . ASN B 1 477 ? 152.558 155.336 195.188 1.00 96.79  ? 477 ASN B N   1 
ATOM   7405  C CA  . ASN B 1 477 ? 153.034 155.452 193.812 1.00 96.79  ? 477 ASN B CA  1 
ATOM   7406  C C   . ASN B 1 477 ? 153.959 154.300 193.442 1.00 96.79  ? 477 ASN B C   1 
ATOM   7407  O O   . ASN B 1 477 ? 153.861 153.745 192.341 1.00 96.79  ? 477 ASN B O   1 
ATOM   7408  C CB  . ASN B 1 477 ? 153.744 156.791 193.611 1.00 96.79  ? 477 ASN B CB  1 
ATOM   7409  C CG  . ASN B 1 477 ? 152.797 157.972 193.676 1.00 96.79  ? 477 ASN B CG  1 
ATOM   7410  O OD1 . ASN B 1 477 ? 151.581 157.816 193.573 1.00 96.79  ? 477 ASN B OD1 1 
ATOM   7411  N ND2 . ASN B 1 477 ? 153.353 159.165 193.842 1.00 96.79  ? 477 ASN B ND2 1 
ATOM   7412  N N   . ALA B 1 478 ? 154.869 153.928 194.345 1.00 95.70  ? 478 ALA B N   1 
ATOM   7413  C CA  . ALA B 1 478 ? 155.742 152.789 194.081 1.00 95.70  ? 478 ALA B CA  1 
ATOM   7414  C C   . ALA B 1 478 ? 154.939 151.499 193.973 1.00 95.70  ? 478 ALA B C   1 
ATOM   7415  O O   . ALA B 1 478 ? 155.267 150.617 193.172 1.00 95.70  ? 478 ALA B O   1 
ATOM   7416  C CB  . ALA B 1 478 ? 156.806 152.677 195.172 1.00 95.70  ? 478 ALA B CB  1 
ATOM   7417  N N   . CYS B 1 479 ? 153.878 151.376 194.774 1.00 94.77  ? 479 CYS B N   1 
ATOM   7418  C CA  . CYS B 1 479 ? 152.982 150.228 194.670 1.00 94.77  ? 479 CYS B CA  1 
ATOM   7419  C C   . CYS B 1 479 ? 152.276 150.200 193.315 1.00 94.77  ? 479 CYS B C   1 
ATOM   7420  O O   . CYS B 1 479 ? 152.151 149.138 192.689 1.00 94.77  ? 479 CYS B O   1 
ATOM   7421  C CB  . CYS B 1 479 ? 151.980 150.274 195.826 1.00 94.77  ? 479 CYS B CB  1 
ATOM   7422  S SG  . CYS B 1 479 ? 150.762 148.950 195.924 1.00 94.77  ? 479 CYS B SG  1 
ATOM   7423  N N   . ILE B 1 480 ? 151.824 151.365 192.838 1.00 92.54  ? 480 ILE B N   1 
ATOM   7424  C CA  . ILE B 1 480 ? 151.217 151.457 191.510 1.00 92.54  ? 480 ILE B CA  1 
ATOM   7425  C C   . ILE B 1 480 ? 152.210 151.019 190.442 1.00 92.54  ? 480 ILE B C   1 
ATOM   7426  O O   . ILE B 1 480 ? 151.868 150.278 189.513 1.00 92.54  ? 480 ILE B O   1 
ATOM   7427  C CB  . ILE B 1 480 ? 150.714 152.888 191.239 1.00 92.54  ? 480 ILE B CB  1 
ATOM   7428  C CG1 . ILE B 1 480 ? 149.598 153.312 192.201 1.00 92.54  ? 480 ILE B CG1 1 
ATOM   7429  C CG2 . ILE B 1 480 ? 150.231 153.014 189.801 1.00 92.54  ? 480 ILE B CG2 1 
ATOM   7430  C CD1 . ILE B 1 480 ? 148.767 152.188 192.757 1.00 92.54  ? 480 ILE B CD1 1 
ATOM   7431  N N   . GLU B 1 481 ? 153.452 151.495 190.545 1.00 93.93  ? 481 GLU B N   1 
ATOM   7432  C CA  . GLU B 1 481 ? 154.459 151.149 189.549 1.00 93.93  ? 481 GLU B CA  1 
ATOM   7433  C C   . GLU B 1 481 ? 154.780 149.661 189.584 1.00 93.93  ? 481 GLU B C   1 
ATOM   7434  O O   . GLU B 1 481 ? 155.011 149.045 188.537 1.00 93.93  ? 481 GLU B O   1 
ATOM   7435  C CB  . GLU B 1 481 ? 155.718 151.985 189.771 1.00 93.93  ? 481 GLU B CB  1 
ATOM   7436  C CG  . GLU B 1 481 ? 156.803 151.764 188.735 1.00 93.93  ? 481 GLU B CG  1 
ATOM   7437  C CD  . GLU B 1 481 ? 158.176 152.156 189.243 1.00 93.93  ? 481 GLU B CD  1 
ATOM   7438  O OE1 . GLU B 1 481 ? 158.250 152.975 190.183 1.00 93.93  ? 481 GLU B OE1 1 
ATOM   7439  O OE2 . GLU B 1 481 ? 159.180 151.647 188.700 1.00 93.93  ? 481 GLU B OE2 1 
ATOM   7440  N N   . SER B 1 482 ? 154.803 149.067 190.780 1.00 93.30  ? 482 SER B N   1 
ATOM   7441  C CA  . SER B 1 482 ? 155.006 147.627 190.889 1.00 93.30  ? 482 SER B CA  1 
ATOM   7442  C C   . SER B 1 482 ? 153.872 146.865 190.218 1.00 93.30  ? 482 SER B C   1 
ATOM   7443  O O   . SER B 1 482 ? 154.106 145.851 189.550 1.00 93.30  ? 482 SER B O   1 
ATOM   7444  C CB  . SER B 1 482 ? 155.128 147.223 192.358 1.00 93.30  ? 482 SER B CB  1 
ATOM   7445  O OG  . SER B 1 482 ? 153.850 147.053 192.947 1.00 93.30  ? 482 SER B OG  1 
ATOM   7446  N N   . ILE B 1 483 ? 152.634 147.332 190.393 1.00 91.47  ? 483 ILE B N   1 
ATOM   7447  C CA  . ILE B 1 483 ? 151.505 146.697 189.715 1.00 91.47  ? 483 ILE B CA  1 
ATOM   7448  C C   . ILE B 1 483 ? 151.655 146.815 188.203 1.00 91.47  ? 483 ILE B C   1 
ATOM   7449  O O   . ILE B 1 483 ? 151.448 145.844 187.464 1.00 91.47  ? 483 ILE B O   1 
ATOM   7450  C CB  . ILE B 1 483 ? 150.175 147.308 190.196 1.00 91.47  ? 483 ILE B CB  1 
ATOM   7451  C CG1 . ILE B 1 483 ? 149.840 146.819 191.603 1.00 91.47  ? 483 ILE B CG1 1 
ATOM   7452  C CG2 . ILE B 1 483 ? 149.048 146.958 189.234 1.00 91.47  ? 483 ILE B CG2 1 
ATOM   7453  C CD1 . ILE B 1 483 ? 148.566 147.401 192.158 1.00 91.47  ? 483 ILE B CD1 1 
ATOM   7454  N N   . ARG B 1 484 ? 152.021 148.003 187.722 1.00 89.54  ? 484 ARG B N   1 
ATOM   7455  C CA  . ARG B 1 484 ? 152.107 148.235 186.283 1.00 89.54  ? 484 ARG B CA  1 
ATOM   7456  C C   . ARG B 1 484 ? 153.220 147.411 185.646 1.00 89.54  ? 484 ARG B C   1 
ATOM   7457  O O   . ARG B 1 484 ? 153.054 146.885 184.540 1.00 89.54  ? 484 ARG B O   1 
ATOM   7458  C CB  . ARG B 1 484 ? 152.316 149.722 186.007 1.00 89.54  ? 484 ARG B CB  1 
ATOM   7459  C CG  . ARG B 1 484 ? 151.070 150.562 186.207 1.00 89.54  ? 484 ARG B CG  1 
ATOM   7460  C CD  . ARG B 1 484 ? 151.111 151.812 185.353 1.00 89.54  ? 484 ARG B CD  1 
ATOM   7461  N NE  . ARG B 1 484 ? 151.082 153.025 186.161 1.00 89.54  ? 484 ARG B NE  1 
ATOM   7462  C CZ  . ARG B 1 484 ? 152.109 153.850 186.311 1.00 89.54  ? 484 ARG B CZ  1 
ATOM   7463  N NH1 . ARG B 1 484 ? 153.272 153.619 185.725 1.00 89.54  ? 484 ARG B NH1 1 
ATOM   7464  N NH2 . ARG B 1 484 ? 151.965 154.935 187.066 1.00 89.54  ? 484 ARG B NH2 1 
ATOM   7465  N N   . ASN B 1 485 ? 154.363 147.294 186.325 1.00 92.76  ? 485 ASN B N   1 
ATOM   7466  C CA  . ASN B 1 485 ? 155.482 146.535 185.774 1.00 92.76  ? 485 ASN B CA  1 
ATOM   7467  C C   . ASN B 1 485 ? 155.160 145.049 185.688 1.00 92.76  ? 485 ASN B C   1 
ATOM   7468  O O   . ASN B 1 485 ? 155.550 144.378 184.726 1.00 92.76  ? 485 ASN B O   1 
ATOM   7469  C CB  . ASN B 1 485 ? 156.734 146.756 186.622 1.00 92.76  ? 485 ASN B CB  1 
ATOM   7470  C CG  . ASN B 1 485 ? 157.472 148.024 186.251 1.00 92.76  ? 485 ASN B CG  1 
ATOM   7471  O OD1 . ASN B 1 485 ? 156.977 148.841 185.477 1.00 92.76  ? 485 ASN B OD1 1 
ATOM   7472  N ND2 . ASN B 1 485 ? 158.670 148.193 186.801 1.00 92.76  ? 485 ASN B ND2 1 
ATOM   7473  N N   . GLY B 1 486 ? 154.457 144.521 186.677 1.00 92.41  ? 486 GLY B N   1 
ATOM   7474  C CA  . GLY B 1 486 ? 154.223 143.104 186.796 1.00 92.41  ? 486 GLY B CA  1 
ATOM   7475  C C   . GLY B 1 486 ? 154.960 142.427 187.935 1.00 92.41  ? 486 GLY B C   1 
ATOM   7476  O O   . GLY B 1 486 ? 155.057 141.194 187.935 1.00 92.41  ? 486 GLY B O   1 
ATOM   7477  N N   . THR B 1 487 ? 155.481 143.189 188.898 1.00 94.83  ? 487 THR B N   1 
ATOM   7478  C CA  . THR B 1 487 ? 156.227 142.648 190.028 1.00 94.83  ? 487 THR B CA  1 
ATOM   7479  C C   . THR B 1 487 ? 155.468 142.806 191.341 1.00 94.83  ? 487 THR B C   1 
ATOM   7480  O O   . THR B 1 487 ? 156.075 142.751 192.415 1.00 94.83  ? 487 THR B O   1 
ATOM   7481  C CB  . THR B 1 487 ? 157.600 143.315 190.129 1.00 94.83  ? 487 THR B CB  1 
ATOM   7482  O OG1 . THR B 1 487 ? 158.257 142.883 191.327 1.00 94.83  ? 487 THR B OG1 1 
ATOM   7483  C CG2 . THR B 1 487 ? 157.453 144.828 190.157 1.00 94.83  ? 487 THR B CG2 1 
ATOM   7484  N N   . TYR B 1 488 ? 154.156 143.006 191.276 1.00 95.12  ? 488 TYR B N   1 
ATOM   7485  C CA  . TYR B 1 488 ? 153.363 143.200 192.481 1.00 95.12  ? 488 TYR B CA  1 
ATOM   7486  C C   . TYR B 1 488 ? 153.248 141.894 193.256 1.00 95.12  ? 488 TYR B C   1 
ATOM   7487  O O   . TYR B 1 488 ? 152.887 140.855 192.696 1.00 95.12  ? 488 TYR B O   1 
ATOM   7488  C CB  . TYR B 1 488 ? 151.978 143.730 192.112 1.00 95.12  ? 488 TYR B CB  1 
ATOM   7489  C CG  . TYR B 1 488 ? 150.976 143.734 193.245 1.00 95.12  ? 488 TYR B CG  1 
ATOM   7490  C CD1 . TYR B 1 488 ? 150.992 144.728 194.211 1.00 95.12  ? 488 TYR B CD1 1 
ATOM   7491  C CD2 . TYR B 1 488 ? 150.000 142.750 193.334 1.00 95.12  ? 488 TYR B CD2 1 
ATOM   7492  C CE1 . TYR B 1 488 ? 150.072 144.737 195.242 1.00 95.12  ? 488 TYR B CE1 1 
ATOM   7493  C CE2 . TYR B 1 488 ? 149.079 142.751 194.360 1.00 95.12  ? 488 TYR B CE2 1 
ATOM   7494  C CZ  . TYR B 1 488 ? 149.118 143.746 195.311 1.00 95.12  ? 488 TYR B CZ  1 
ATOM   7495  O OH  . TYR B 1 488 ? 148.199 143.747 196.333 1.00 95.12  ? 488 TYR B OH  1 
ATOM   7496  N N   . ASP B 1 489 ? 153.552 141.950 194.549 1.00 98.64  ? 489 ASP B N   1 
ATOM   7497  C CA  . ASP B 1 489 ? 153.490 140.794 195.434 1.00 98.64  ? 489 ASP B CA  1 
ATOM   7498  C C   . ASP B 1 489 ? 152.319 140.980 196.388 1.00 98.64  ? 489 ASP B C   1 
ATOM   7499  O O   . ASP B 1 489 ? 152.327 141.899 197.213 1.00 98.64  ? 489 ASP B O   1 
ATOM   7500  C CB  . ASP B 1 489 ? 154.799 140.628 196.205 1.00 98.64  ? 489 ASP B CB  1 
ATOM   7501  C CG  . ASP B 1 489 ? 154.825 139.369 197.049 1.00 98.64  ? 489 ASP B CG  1 
ATOM   7502  O OD1 . ASP B 1 489 ? 154.109 138.405 196.708 1.00 98.64  ? 489 ASP B OD1 1 
ATOM   7503  O OD2 . ASP B 1 489 ? 155.568 139.343 198.051 1.00 98.64  ? 489 ASP B OD2 1 
ATOM   7504  N N   . HIS B 1 490 ? 151.315 140.108 196.275 1.00 98.75  ? 490 HIS B N   1 
ATOM   7505  C CA  . HIS B 1 490 ? 150.094 140.286 197.052 1.00 98.75  ? 490 HIS B CA  1 
ATOM   7506  C C   . HIS B 1 490 ? 150.270 139.885 198.512 1.00 98.75  ? 490 HIS B C   1 
ATOM   7507  O O   . HIS B 1 490 ? 149.690 140.528 199.396 1.00 98.75  ? 490 HIS B O   1 
ATOM   7508  C CB  . HIS B 1 490 ? 148.945 139.501 196.414 1.00 98.75  ? 490 HIS B CB  1 
ATOM   7509  C CG  . HIS B 1 490 ? 149.144 138.018 196.410 1.00 98.75  ? 490 HIS B CG  1 
ATOM   7510  N ND1 . HIS B 1 490 ? 150.152 137.401 195.701 1.00 98.75  ? 490 HIS B ND1 1 
ATOM   7511  C CD2 . HIS B 1 490 ? 148.454 137.026 197.022 1.00 98.75  ? 490 HIS B CD2 1 
ATOM   7512  C CE1 . HIS B 1 490 ? 150.078 136.095 195.881 1.00 98.75  ? 490 HIS B CE1 1 
ATOM   7513  N NE2 . HIS B 1 490 ? 149.057 135.841 196.678 1.00 98.75  ? 490 HIS B NE2 1 
ATOM   7514  N N   . ASP B 1 491 ? 151.071 138.847 198.780 1.00 99.42  ? 491 ASP B N   1 
ATOM   7515  C CA  . ASP B 1 491 ? 151.261 138.371 200.149 1.00 99.42  ? 491 ASP B CA  1 
ATOM   7516  C C   . ASP B 1 491 ? 151.657 139.503 201.087 1.00 99.42  ? 491 ASP B C   1 
ATOM   7517  O O   . ASP B 1 491 ? 151.139 139.602 202.206 1.00 99.42  ? 491 ASP B O   1 
ATOM   7518  C CB  . ASP B 1 491 ? 152.320 137.270 200.179 1.00 99.42  ? 491 ASP B CB  1 
ATOM   7519  C CG  . ASP B 1 491 ? 151.785 135.933 199.715 1.00 99.42  ? 491 ASP B CG  1 
ATOM   7520  O OD1 . ASP B 1 491 ? 150.559 135.720 199.803 1.00 99.42  ? 491 ASP B OD1 1 
ATOM   7521  O OD2 . ASP B 1 491 ? 152.593 135.094 199.263 1.00 99.42  ? 491 ASP B OD2 1 
ATOM   7522  N N   . ILE B 1 492 ? 152.545 140.389 200.626 1.00 98.36  ? 492 ILE B N   1 
ATOM   7523  C CA  . ILE B 1 492 ? 153.041 141.478 201.462 1.00 98.36  ? 492 ILE B CA  1 
ATOM   7524  C C   . ILE B 1 492 ? 151.885 142.305 202.003 1.00 98.36  ? 492 ILE B C   1 
ATOM   7525  O O   . ILE B 1 492 ? 151.884 142.714 203.171 1.00 98.36  ? 492 ILE B O   1 
ATOM   7526  C CB  . ILE B 1 492 ? 154.033 142.347 200.666 1.00 98.36  ? 492 ILE B CB  1 
ATOM   7527  C CG1 . ILE B 1 492 ? 155.329 141.580 200.407 1.00 98.36  ? 492 ILE B CG1 1 
ATOM   7528  C CG2 . ILE B 1 492 ? 154.320 143.651 201.397 1.00 98.36  ? 492 ILE B CG2 1 
ATOM   7529  C CD1 . ILE B 1 492 ? 156.248 142.253 199.410 1.00 98.36  ? 492 ILE B CD1 1 
ATOM   7530  N N   . TYR B 1 493 ? 150.874 142.550 201.172 1.00 99.10  ? 493 TYR B N   1 
ATOM   7531  C CA  . TYR B 1 493 ? 149.720 143.340 201.576 1.00 99.10  ? 493 TYR B CA  1 
ATOM   7532  C C   . TYR B 1 493 ? 148.484 142.481 201.814 1.00 99.10  ? 493 TYR B C   1 
ATOM   7533  O O   . TYR B 1 493 ? 147.371 143.012 201.880 1.00 99.10  ? 493 TYR B O   1 
ATOM   7534  C CB  . TYR B 1 493 ? 149.420 144.412 200.529 1.00 99.10  ? 493 TYR B CB  1 
ATOM   7535  C CG  . TYR B 1 493 ? 150.609 145.256 200.133 1.00 99.10  ? 493 TYR B CG  1 
ATOM   7536  C CD1 . TYR B 1 493 ? 151.002 146.340 200.903 1.00 99.10  ? 493 TYR B CD1 1 
ATOM   7537  C CD2 . TYR B 1 493 ? 151.330 144.976 198.980 1.00 99.10  ? 493 TYR B CD2 1 
ATOM   7538  C CE1 . TYR B 1 493 ? 152.084 147.116 200.544 1.00 99.10  ? 493 TYR B CE1 1 
ATOM   7539  C CE2 . TYR B 1 493 ? 152.415 145.746 198.612 1.00 99.10  ? 493 TYR B CE2 1 
ATOM   7540  C CZ  . TYR B 1 493 ? 152.787 146.816 199.397 1.00 99.10  ? 493 TYR B CZ  1 
ATOM   7541  O OH  . TYR B 1 493 ? 153.866 147.588 199.036 1.00 99.10  ? 493 TYR B OH  1 
ATOM   7542  N N   . ARG B 1 494 ? 148.655 141.164 201.941 1.00 99.80  ? 494 ARG B N   1 
ATOM   7543  C CA  . ARG B 1 494 ? 147.499 140.275 201.994 1.00 99.80  ? 494 ARG B CA  1 
ATOM   7544  C C   . ARG B 1 494 ? 146.665 140.518 203.248 1.00 99.80  ? 494 ARG B C   1 
ATOM   7545  O O   . ARG B 1 494 ? 145.524 140.995 203.167 1.00 99.80  ? 494 ARG B O   1 
ATOM   7546  C CB  . ARG B 1 494 ? 147.966 138.819 201.926 1.00 99.80  ? 494 ARG B CB  1 
ATOM   7547  C CG  . ARG B 1 494 ? 146.851 137.809 201.725 1.00 99.80  ? 494 ARG B CG  1 
ATOM   7548  C CD  . ARG B 1 494 ? 147.409 136.402 201.590 1.00 99.80  ? 494 ARG B CD  1 
ATOM   7549  N NE  . ARG B 1 494 ? 146.361 135.419 201.341 1.00 99.80  ? 494 ARG B NE  1 
ATOM   7550  C CZ  . ARG B 1 494 ? 145.837 135.167 200.150 1.00 99.80  ? 494 ARG B CZ  1 
ATOM   7551  N NH1 . ARG B 1 494 ? 146.248 135.804 199.066 1.00 99.80  ? 494 ARG B NH1 1 
ATOM   7552  N NH2 . ARG B 1 494 ? 144.875 134.255 200.044 1.00 99.80  ? 494 ARG B NH2 1 
ATOM   7553  N N   . ASP B 1 495 ? 147.246 140.253 204.423 1.00 101.23 ? 495 ASP B N   1 
ATOM   7554  C CA  . ASP B 1 495 ? 146.473 140.227 205.662 1.00 101.23 ? 495 ASP B CA  1 
ATOM   7555  C C   . ASP B 1 495 ? 145.738 141.540 205.887 1.00 101.23 ? 495 ASP B C   1 
ATOM   7556  O O   . ASP B 1 495 ? 144.542 141.550 206.205 1.00 101.23 ? 495 ASP B O   1 
ATOM   7557  C CB  . ASP B 1 495 ? 147.393 139.922 206.845 1.00 101.23 ? 495 ASP B CB  1 
ATOM   7558  C CG  . ASP B 1 495 ? 148.380 138.814 206.545 1.00 101.23 ? 495 ASP B CG  1 
ATOM   7559  O OD1 . ASP B 1 495 ? 147.938 137.693 206.216 1.00 101.23 ? 495 ASP B OD1 1 
ATOM   7560  O OD2 . ASP B 1 495 ? 149.600 139.066 206.637 1.00 101.23 ? 495 ASP B OD2 1 
ATOM   7561  N N   . GLU B 1 496 ? 146.439 142.661 205.700 1.00 100.82 ? 496 GLU B N   1 
ATOM   7562  C CA  . GLU B 1 496 ? 145.825 143.970 205.889 1.00 100.82 ? 496 GLU B CA  1 
ATOM   7563  C C   . GLU B 1 496 ? 144.559 144.107 205.053 1.00 100.82 ? 496 GLU B C   1 
ATOM   7564  O O   . GLU B 1 496 ? 143.500 144.488 205.566 1.00 100.82 ? 496 GLU B O   1 
ATOM   7565  C CB  . GLU B 1 496 ? 146.827 145.071 205.538 1.00 100.82 ? 496 GLU B CB  1 
ATOM   7566  C CG  . GLU B 1 496 ? 146.185 146.400 205.187 1.00 100.82 ? 496 GLU B CG  1 
ATOM   7567  C CD  . GLU B 1 496 ? 147.191 147.424 204.696 1.00 100.82 ? 496 GLU B CD  1 
ATOM   7568  O OE1 . GLU B 1 496 ? 148.368 147.057 204.503 1.00 100.82 ? 496 GLU B OE1 1 
ATOM   7569  O OE2 . GLU B 1 496 ? 146.803 148.595 204.503 1.00 100.82 ? 496 GLU B OE2 1 
ATOM   7570  N N   . ALA B 1 497 ? 144.641 143.763 203.764 1.00 101.18 ? 497 ALA B N   1 
ATOM   7571  C CA  . ALA B 1 497 ? 143.462 143.873 202.914 1.00 101.18 ? 497 ALA B CA  1 
ATOM   7572  C C   . ALA B 1 497 ? 142.364 142.933 203.388 1.00 101.18 ? 497 ALA B C   1 
ATOM   7573  O O   . ALA B 1 497 ? 141.177 143.281 203.348 1.00 101.18 ? 497 ALA B O   1 
ATOM   7574  C CB  . ALA B 1 497 ? 143.826 143.593 201.459 1.00 101.18 ? 497 ALA B CB  1 
ATOM   7575  N N   . LEU B 1 498 ? 142.745 141.752 203.880 1.00 101.73 ? 498 LEU B N   1 
ATOM   7576  C CA  . LEU B 1 498 ? 141.760 140.811 204.392 1.00 101.73 ? 498 LEU B CA  1 
ATOM   7577  C C   . LEU B 1 498 ? 141.040 141.337 205.623 1.00 101.73 ? 498 LEU B C   1 
ATOM   7578  O O   . LEU B 1 498 ? 140.017 140.765 206.012 1.00 101.73 ? 498 LEU B O   1 
ATOM   7579  C CB  . LEU B 1 498 ? 142.421 139.469 204.708 1.00 101.73 ? 498 LEU B CB  1 
ATOM   7580  C CG  . LEU B 1 498 ? 142.398 138.456 203.564 1.00 101.73 ? 498 LEU B CG  1 
ATOM   7581  C CD1 . LEU B 1 498 ? 142.692 137.052 204.071 1.00 101.73 ? 498 LEU B CD1 1 
ATOM   7582  C CD2 . LEU B 1 498 ? 141.060 138.502 202.841 1.00 101.73 ? 498 LEU B CD2 1 
ATOM   7583  N N   . ASN B 1 499 ? 141.547 142.401 206.245 1.00 102.41 ? 499 ASN B N   1 
ATOM   7584  C CA  . ASN B 1 499 ? 140.810 143.070 207.306 1.00 102.41 ? 499 ASN B CA  1 
ATOM   7585  C C   . ASN B 1 499 ? 139.953 144.209 206.777 1.00 102.41 ? 499 ASN B C   1 
ATOM   7586  O O   . ASN B 1 499 ? 138.897 144.500 207.350 1.00 102.41 ? 499 ASN B O   1 
ATOM   7587  C CB  . ASN B 1 499 ? 141.776 143.604 208.366 1.00 102.41 ? 499 ASN B CB  1 
ATOM   7588  C CG  . ASN B 1 499 ? 142.495 142.496 209.107 1.00 102.41 ? 499 ASN B CG  1 
ATOM   7589  O OD1 . ASN B 1 499 ? 141.991 141.378 209.217 1.00 102.41 ? 499 ASN B OD1 1 
ATOM   7590  N ND2 . ASN B 1 499 ? 143.682 142.800 209.618 1.00 102.41 ? 499 ASN B ND2 1 
ATOM   7591  N N   . ASN B 1 500 ? 140.385 144.859 205.694 1.00 101.48 ? 500 ASN B N   1 
ATOM   7592  C CA  . ASN B 1 500 ? 139.616 145.968 205.143 1.00 101.48 ? 500 ASN B CA  1 
ATOM   7593  C C   . ASN B 1 500 ? 138.397 145.475 204.375 1.00 101.48 ? 500 ASN B C   1 
ATOM   7594  O O   . ASN B 1 500 ? 137.341 146.117 204.404 1.00 101.48 ? 500 ASN B O   1 
ATOM   7595  C CB  . ASN B 1 500 ? 140.504 146.827 204.243 1.00 101.48 ? 500 ASN B CB  1 
ATOM   7596  C CG  . ASN B 1 500 ? 140.946 148.112 204.916 1.00 101.48 ? 500 ASN B CG  1 
ATOM   7597  O OD1 . ASN B 1 500 ? 140.250 148.645 205.780 1.00 101.48 ? 500 ASN B OD1 1 
ATOM   7598  N ND2 . ASN B 1 500 ? 142.107 148.617 204.521 1.00 101.48 ? 500 ASN B ND2 1 
ATOM   7599  N N   . ARG B 1 501 ? 138.522 144.340 203.688 1.00 101.59 ? 501 ARG B N   1 
ATOM   7600  C CA  . ARG B 1 501 ? 137.420 143.841 202.874 1.00 101.59 ? 501 ARG B CA  1 
ATOM   7601  C C   . ARG B 1 501 ? 136.306 143.252 203.731 1.00 101.59 ? 501 ARG B C   1 
ATOM   7602  O O   . ARG B 1 501 ? 135.123 143.493 203.465 1.00 101.59 ? 501 ARG B O   1 
ATOM   7603  C CB  . ARG B 1 501 ? 137.936 142.805 201.875 1.00 101.59 ? 501 ARG B CB  1 
ATOM   7604  C CG  . ARG B 1 501 ? 136.874 142.278 200.927 1.00 101.59 ? 501 ARG B CG  1 
ATOM   7605  C CD  . ARG B 1 501 ? 137.387 142.209 199.495 1.00 101.59 ? 501 ARG B CD  1 
ATOM   7606  N NE  . ARG B 1 501 ? 138.506 141.286 199.345 1.00 101.59 ? 501 ARG B NE  1 
ATOM   7607  C CZ  . ARG B 1 501 ? 138.479 140.197 198.590 1.00 101.59 ? 501 ARG B CZ  1 
ATOM   7608  N NH1 . ARG B 1 501 ? 137.404 139.865 197.894 1.00 101.59 ? 501 ARG B NH1 1 
ATOM   7609  N NH2 . ARG B 1 501 ? 139.558 139.423 198.528 1.00 101.59 ? 501 ARG B NH2 1 
ATOM   7610  N N   . PHE B 1 502 ? 136.659 142.490 204.760 1.00 103.45 ? 502 PHE B N   1 
ATOM   7611  C CA  . PHE B 1 502 ? 135.661 141.816 205.580 1.00 103.45 ? 502 PHE B CA  1 
ATOM   7612  C C   . PHE B 1 502 ? 135.586 142.427 206.974 1.00 103.45 ? 502 PHE B C   1 
ATOM   7613  O O   . PHE B 1 502 ? 134.500 142.716 207.476 1.00 103.45 ? 502 PHE B O   1 
ATOM   7614  C CB  . PHE B 1 502 ? 135.974 140.322 205.671 1.00 103.45 ? 502 PHE B CB  1 
ATOM   7615  C CG  . PHE B 1 502 ? 136.001 139.628 204.339 1.00 103.45 ? 502 PHE B CG  1 
ATOM   7616  C CD1 . PHE B 1 502 ? 135.131 140.005 203.329 1.00 103.45 ? 502 PHE B CD1 1 
ATOM   7617  C CD2 . PHE B 1 502 ? 136.899 138.604 204.095 1.00 103.45 ? 502 PHE B CD2 1 
ATOM   7618  C CE1 . PHE B 1 502 ? 135.154 139.370 202.101 1.00 103.45 ? 502 PHE B CE1 1 
ATOM   7619  C CE2 . PHE B 1 502 ? 136.927 137.965 202.868 1.00 103.45 ? 502 PHE B CE2 1 
ATOM   7620  C CZ  . PHE B 1 502 ? 136.053 138.350 201.870 1.00 103.45 ? 502 PHE B CZ  1 
ATOM   7621  N N   . THR C 1 12  ? 118.059 133.469 201.138 1.00 96.20  ? 12  THR C N   1 
ATOM   7622  C CA  . THR C 1 12  ? 118.715 133.356 199.841 1.00 96.20  ? 12  THR C CA  1 
ATOM   7623  C C   . THR C 1 12  ? 117.723 133.554 198.699 1.00 96.20  ? 12  THR C C   1 
ATOM   7624  O O   . THR C 1 12  ? 116.519 133.667 198.921 1.00 96.20  ? 12  THR C O   1 
ATOM   7625  C CB  . THR C 1 12  ? 119.405 131.989 199.674 1.00 96.20  ? 12  THR C CB  1 
ATOM   7626  O OG1 . THR C 1 12  ? 118.428 130.943 199.755 1.00 96.20  ? 12  THR C OG1 1 
ATOM   7627  C CG2 . THR C 1 12  ? 120.455 131.784 200.754 1.00 96.20  ? 12  THR C CG2 1 
ATOM   7628  N N   . ALA C 1 13  ? 118.243 133.604 197.474 1.00 94.14  ? 13  ALA C N   1 
ATOM   7629  C CA  . ALA C 1 13  ? 117.414 133.736 196.285 1.00 94.14  ? 13  ALA C CA  1 
ATOM   7630  C C   . ALA C 1 13  ? 118.195 133.213 195.090 1.00 94.14  ? 13  ALA C C   1 
ATOM   7631  O O   . ALA C 1 13  ? 119.417 133.065 195.148 1.00 94.14  ? 13  ALA C O   1 
ATOM   7632  C CB  . ALA C 1 13  ? 116.980 135.188 196.058 1.00 94.14  ? 13  ALA C CB  1 
ATOM   7633  N N   . THR C 1 14  ? 117.485 132.931 194.000 1.00 89.75  ? 14  THR C N   1 
ATOM   7634  C CA  . THR C 1 14  ? 118.118 132.443 192.782 1.00 89.75  ? 14  THR C CA  1 
ATOM   7635  C C   . THR C 1 14  ? 117.806 133.379 191.625 1.00 89.75  ? 14  THR C C   1 
ATOM   7636  O O   . THR C 1 14  ? 116.657 133.788 191.441 1.00 89.75  ? 14  THR C O   1 
ATOM   7637  C CB  . THR C 1 14  ? 117.651 131.026 192.437 1.00 89.75  ? 14  THR C CB  1 
ATOM   7638  O OG1 . THR C 1 14  ? 117.565 130.243 193.634 1.00 89.75  ? 14  THR C OG1 1 
ATOM   7639  C CG2 . THR C 1 14  ? 118.623 130.364 191.469 1.00 89.75  ? 14  THR C CG2 1 
ATOM   7640  N N   . LEU C 1 15  ? 118.830 133.697 190.835 1.00 84.68  ? 15  LEU C N   1 
ATOM   7641  C CA  . LEU C 1 15  ? 118.676 134.557 189.665 1.00 84.68  ? 15  LEU C CA  1 
ATOM   7642  C C   . LEU C 1 15  ? 119.398 133.910 188.493 1.00 84.68  ? 15  LEU C C   1 
ATOM   7643  O O   . LEU C 1 15  ? 120.627 133.831 188.484 1.00 84.68  ? 15  LEU C O   1 
ATOM   7644  C CB  . LEU C 1 15  ? 119.215 135.960 189.929 1.00 84.68  ? 15  LEU C CB  1 
ATOM   7645  C CG  . LEU C 1 15  ? 118.922 136.952 188.806 1.00 84.68  ? 15  LEU C CG  1 
ATOM   7646  C CD1 . LEU C 1 15  ? 117.427 137.195 188.702 1.00 84.68  ? 15  LEU C CD1 1 
ATOM   7647  C CD2 . LEU C 1 15  ? 119.665 138.248 189.051 1.00 84.68  ? 15  LEU C CD2 1 
ATOM   7648  N N   . CYS C 1 16  ? 118.640 133.437 187.517 1.00 80.93  ? 16  CYS C N   1 
ATOM   7649  C CA  . CYS C 1 16  ? 119.193 132.721 186.381 1.00 80.93  ? 16  CYS C CA  1 
ATOM   7650  C C   . CYS C 1 16  ? 119.002 133.526 185.102 1.00 80.93  ? 16  CYS C C   1 
ATOM   7651  O O   . CYS C 1 16  ? 118.057 134.306 184.975 1.00 80.93  ? 16  CYS C O   1 
ATOM   7652  C CB  . CYS C 1 16  ? 118.527 131.354 186.261 1.00 80.93  ? 16  CYS C CB  1 
ATOM   7653  S SG  . CYS C 1 16  ? 118.958 130.283 187.641 1.00 80.93  ? 16  CYS C SG  1 
ATOM   7654  N N   . LEU C 1 17  ? 119.915 133.333 184.155 1.00 75.21  ? 17  LEU C N   1 
ATOM   7655  C CA  . LEU C 1 17  ? 119.878 134.017 182.870 1.00 75.21  ? 17  LEU C CA  1 
ATOM   7656  C C   . LEU C 1 17  ? 119.721 132.988 181.761 1.00 75.21  ? 17  LEU C C   1 
ATOM   7657  O O   . LEU C 1 17  ? 120.283 131.891 181.842 1.00 75.21  ? 17  LEU C O   1 
ATOM   7658  C CB  . LEU C 1 17  ? 121.147 134.843 182.656 1.00 75.21  ? 17  LEU C CB  1 
ATOM   7659  C CG  . LEU C 1 17  ? 121.279 136.088 183.531 1.00 75.21  ? 17  LEU C CG  1 
ATOM   7660  C CD1 . LEU C 1 17  ? 122.348 135.881 184.584 1.00 75.21  ? 17  LEU C CD1 1 
ATOM   7661  C CD2 . LEU C 1 17  ? 121.619 137.284 182.671 1.00 75.21  ? 17  LEU C CD2 1 
ATOM   7662  N N   . GLY C 1 18  ? 118.952 133.332 180.730 1.00 70.50  ? 18  GLY C N   1 
ATOM   7663  C CA  . GLY C 1 18  ? 118.687 132.352 179.696 1.00 70.50  ? 18  GLY C CA  1 
ATOM   7664  C C   . GLY C 1 18  ? 118.276 132.977 178.381 1.00 70.50  ? 18  GLY C C   1 
ATOM   7665  O O   . GLY C 1 18  ? 118.089 134.191 178.269 1.00 70.50  ? 18  GLY C O   1 
ATOM   7666  N N   . HIS C 1 19  ? 118.137 132.113 177.376 1.00 66.98  ? 19  HIS C N   1 
ATOM   7667  C CA  . HIS C 1 19  ? 117.778 132.509 176.023 1.00 66.98  ? 19  HIS C CA  1 
ATOM   7668  C C   . HIS C 1 19  ? 116.699 131.579 175.482 1.00 66.98  ? 19  HIS C C   1 
ATOM   7669  O O   . HIS C 1 19  ? 116.562 130.432 175.913 1.00 66.98  ? 19  HIS C O   1 
ATOM   7670  C CB  . HIS C 1 19  ? 119.002 132.512 175.093 1.00 66.98  ? 19  HIS C CB  1 
ATOM   7671  C CG  . HIS C 1 19  ? 119.633 131.166 174.914 1.00 66.98  ? 19  HIS C CG  1 
ATOM   7672  N ND1 . HIS C 1 19  ? 119.076 130.176 174.136 1.00 66.98  ? 19  HIS C ND1 1 
ATOM   7673  C CD2 . HIS C 1 19  ? 120.777 130.648 175.418 1.00 66.98  ? 19  HIS C CD2 1 
ATOM   7674  C CE1 . HIS C 1 19  ? 119.848 129.105 174.168 1.00 66.98  ? 19  HIS C CE1 1 
ATOM   7675  N NE2 . HIS C 1 19  ? 120.888 129.365 174.940 1.00 66.98  ? 19  HIS C NE2 1 
ATOM   7676  N N   . HIS C 1 20  ? 115.938 132.092 174.520 1.00 66.44  ? 20  HIS C N   1 
ATOM   7677  C CA  . HIS C 1 20  ? 114.765 131.401 174.007 1.00 66.44  ? 20  HIS C CA  1 
ATOM   7678  C C   . HIS C 1 20  ? 115.151 130.277 173.048 1.00 66.44  ? 20  HIS C C   1 
ATOM   7679  O O   . HIS C 1 20  ? 116.277 130.201 172.550 1.00 66.44  ? 20  HIS C O   1 
ATOM   7680  C CB  . HIS C 1 20  ? 113.831 132.390 173.308 1.00 66.44  ? 20  HIS C CB  1 
ATOM   7681  C CG  . HIS C 1 20  ? 114.229 132.711 171.901 1.00 66.44  ? 20  HIS C CG  1 
ATOM   7682  N ND1 . HIS C 1 20  ? 115.526 133.013 171.543 1.00 66.44  ? 20  HIS C ND1 1 
ATOM   7683  C CD2 . HIS C 1 20  ? 113.500 132.783 170.763 1.00 66.44  ? 20  HIS C CD2 1 
ATOM   7684  C CE1 . HIS C 1 20  ? 115.578 133.253 170.246 1.00 66.44  ? 20  HIS C CE1 1 
ATOM   7685  N NE2 . HIS C 1 20  ? 114.362 133.121 169.749 1.00 66.44  ? 20  HIS C NE2 1 
ATOM   7686  N N   . SER C 1 21  ? 114.185 129.396 172.792 1.00 66.23  ? 21  SER C N   1 
ATOM   7687  C CA  . SER C 1 21  ? 114.355 128.291 171.858 1.00 66.23  ? 21  SER C CA  1 
ATOM   7688  C C   . SER C 1 21  ? 113.007 127.984 171.218 1.00 66.23  ? 21  SER C C   1 
ATOM   7689  O O   . SER C 1 21  ? 111.957 128.415 171.699 1.00 66.23  ? 21  SER C O   1 
ATOM   7690  C CB  . SER C 1 21  ? 114.927 127.052 172.551 1.00 66.23  ? 21  SER C CB  1 
ATOM   7691  O OG  . SER C 1 21  ? 114.016 126.538 173.502 1.00 66.23  ? 21  SER C OG  1 
ATOM   7692  N N   . VAL C 1 22  ? 113.044 127.230 170.122 1.00 62.34  ? 22  VAL C N   1 
ATOM   7693  C CA  . VAL C 1 22  ? 111.835 126.907 169.366 1.00 62.34  ? 22  VAL C CA  1 
ATOM   7694  C C   . VAL C 1 22  ? 111.728 125.396 169.190 1.00 62.34  ? 22  VAL C C   1 
ATOM   7695  O O   . VAL C 1 22  ? 112.753 124.699 169.188 1.00 62.34  ? 22  VAL C O   1 
ATOM   7696  C CB  . VAL C 1 22  ? 111.819 127.625 168.006 1.00 62.34  ? 22  VAL C CB  1 
ATOM   7697  C CG1 . VAL C 1 22  ? 111.711 129.130 168.199 1.00 62.34  ? 22  VAL C CG1 1 
ATOM   7698  C CG2 . VAL C 1 22  ? 113.056 127.270 167.201 1.00 62.34  ? 22  VAL C CG2 1 
ATOM   7699  N N   . PRO C 1 23  ? 110.517 124.844 169.051 1.00 64.11  ? 23  PRO C N   1 
ATOM   7700  C CA  . PRO C 1 23  ? 110.397 123.382 168.927 1.00 64.11  ? 23  PRO C CA  1 
ATOM   7701  C C   . PRO C 1 23  ? 110.918 122.831 167.611 1.00 64.11  ? 23  PRO C C   1 
ATOM   7702  O O   . PRO C 1 23  ? 111.350 121.673 167.573 1.00 64.11  ? 23  PRO C O   1 
ATOM   7703  C CB  . PRO C 1 23  ? 108.889 123.136 169.082 1.00 64.11  ? 23  PRO C CB  1 
ATOM   7704  C CG  . PRO C 1 23  ? 108.248 124.433 168.738 1.00 64.11  ? 23  PRO C CG  1 
ATOM   7705  C CD  . PRO C 1 23  ? 109.205 125.506 169.150 1.00 64.11  ? 23  PRO C CD  1 
ATOM   7706  N N   . ASN C 1 24  ? 110.889 123.610 166.532 1.00 63.15  ? 24  ASN C N   1 
ATOM   7707  C CA  . ASN C 1 24  ? 111.339 123.156 165.219 1.00 63.15  ? 24  ASN C CA  1 
ATOM   7708  C C   . ASN C 1 24  ? 112.353 124.151 164.665 1.00 63.15  ? 24  ASN C C   1 
ATOM   7709  O O   . ASN C 1 24  ? 111.990 125.265 164.275 1.00 63.15  ? 24  ASN C O   1 
ATOM   7710  C CB  . ASN C 1 24  ? 110.153 122.987 164.269 1.00 63.15  ? 24  ASN C CB  1 
ATOM   7711  C CG  . ASN C 1 24  ? 109.234 124.192 164.264 1.00 63.15  ? 24  ASN C CG  1 
ATOM   7712  O OD1 . ASN C 1 24  ? 109.186 124.954 165.230 1.00 63.15  ? 24  ASN C OD1 1 
ATOM   7713  N ND2 . ASN C 1 24  ? 108.501 124.372 163.173 1.00 63.15  ? 24  ASN C ND2 1 
ATOM   7714  N N   . GLY C 1 25  ? 113.623 123.746 164.629 1.00 56.51  ? 25  GLY C N   1 
ATOM   7715  C CA  . GLY C 1 25  ? 114.692 124.564 164.105 1.00 56.51  ? 25  GLY C CA  1 
ATOM   7716  C C   . GLY C 1 25  ? 115.121 124.144 162.707 1.00 56.51  ? 25  GLY C C   1 
ATOM   7717  O O   . GLY C 1 25  ? 114.649 123.160 162.143 1.00 56.51  ? 25  GLY C O   1 
ATOM   7718  N N   . THR C 1 26  ? 116.049 124.922 162.155 1.00 51.07  ? 26  THR C N   1 
ATOM   7719  C CA  . THR C 1 26  ? 116.550 124.718 160.802 1.00 51.07  ? 26  THR C CA  1 
ATOM   7720  C C   . THR C 1 26  ? 118.061 124.536 160.824 1.00 51.07  ? 26  THR C C   1 
ATOM   7721  O O   . THR C 1 26  ? 118.764 125.210 161.577 1.00 51.07  ? 26  THR C O   1 
ATOM   7722  C CB  . THR C 1 26  ? 116.182 125.896 159.895 1.00 51.07  ? 26  THR C CB  1 
ATOM   7723  O OG1 . THR C 1 26  ? 116.450 127.127 160.575 1.00 51.07  ? 26  THR C OG1 1 
ATOM   7724  C CG2 . THR C 1 26  ? 114.713 125.844 159.528 1.00 51.07  ? 26  THR C CG2 1 
ATOM   7725  N N   . ILE C 1 27  ? 118.559 123.633 159.984 1.00 47.67  ? 27  ILE C N   1 
ATOM   7726  C CA  . ILE C 1 27  ? 119.976 123.284 159.945 1.00 47.67  ? 27  ILE C CA  1 
ATOM   7727  C C   . ILE C 1 27  ? 120.666 124.119 158.875 1.00 47.67  ? 27  ILE C C   1 
ATOM   7728  O O   . ILE C 1 27  ? 120.179 124.217 157.742 1.00 47.67  ? 27  ILE C O   1 
ATOM   7729  C CB  . ILE C 1 27  ? 120.169 121.781 159.684 1.00 47.67  ? 27  ILE C CB  1 
ATOM   7730  C CG1 . ILE C 1 27  ? 119.875 120.983 160.955 1.00 47.67  ? 27  ILE C CG1 1 
ATOM   7731  C CG2 . ILE C 1 27  ? 121.576 121.493 159.187 1.00 47.67  ? 27  ILE C CG2 1 
ATOM   7732  C CD1 . ILE C 1 27  ? 119.000 119.779 160.727 1.00 47.67  ? 27  ILE C CD1 1 
ATOM   7733  N N   . VAL C 1 28  ? 121.794 124.733 159.237 1.00 44.88  ? 28  VAL C N   1 
ATOM   7734  C CA  . VAL C 1 28  ? 122.614 125.520 158.328 1.00 44.88  ? 28  VAL C CA  1 
ATOM   7735  C C   . VAL C 1 28  ? 124.068 125.076 158.472 1.00 44.88  ? 28  VAL C C   1 
ATOM   7736  O O   . VAL C 1 28  ? 124.410 124.259 159.326 1.00 44.88  ? 28  VAL C O   1 
ATOM   7737  C CB  . VAL C 1 28  ? 122.479 127.039 158.573 1.00 44.88  ? 28  VAL C CB  1 
ATOM   7738  C CG1 . VAL C 1 28  ? 121.043 127.494 158.380 1.00 44.88  ? 28  VAL C CG1 1 
ATOM   7739  C CG2 . VAL C 1 28  ? 122.982 127.405 159.956 1.00 44.88  ? 28  VAL C CG2 1 
ATOM   7740  N N   . LYS C 1 29  ? 124.925 125.638 157.622 1.00 44.27  ? 29  LYS C N   1 
ATOM   7741  C CA  . LYS C 1 29  ? 126.342 125.311 157.572 1.00 44.27  ? 29  LYS C CA  1 
ATOM   7742  C C   . LYS C 1 29  ? 127.176 126.561 157.816 1.00 44.27  ? 29  LYS C C   1 
ATOM   7743  O O   . LYS C 1 29  ? 126.856 127.639 157.306 1.00 44.27  ? 29  LYS C O   1 
ATOM   7744  C CB  . LYS C 1 29  ? 126.708 124.695 156.217 1.00 44.27  ? 29  LYS C CB  1 
ATOM   7745  C CG  . LYS C 1 29  ? 128.150 124.246 156.098 1.00 44.27  ? 29  LYS C CG  1 
ATOM   7746  C CD  . LYS C 1 29  ? 128.365 123.406 154.849 1.00 44.27  ? 29  LYS C CD  1 
ATOM   7747  C CE  . LYS C 1 29  ? 128.461 124.279 153.611 1.00 44.27  ? 29  LYS C CE  1 
ATOM   7748  N NZ  . LYS C 1 29  ? 127.566 123.801 152.525 1.00 44.27  ? 29  LYS C NZ  1 
ATOM   7749  N N   . THR C 1 30  ? 128.243 126.417 158.595 1.00 43.82  ? 30  THR C N   1 
ATOM   7750  C CA  . THR C 1 30  ? 129.175 127.500 158.887 1.00 43.82  ? 30  THR C CA  1 
ATOM   7751  C C   . THR C 1 30  ? 130.582 127.114 158.438 1.00 43.82  ? 30  THR C C   1 
ATOM   7752  O O   . THR C 1 30  ? 130.814 126.034 157.894 1.00 43.82  ? 30  THR C O   1 
ATOM   7753  C CB  . THR C 1 30  ? 129.170 127.854 160.380 1.00 43.82  ? 30  THR C CB  1 
ATOM   7754  O OG1 . THR C 1 30  ? 129.638 126.736 161.144 1.00 43.82  ? 30  THR C OG1 1 
ATOM   7755  C CG2 . THR C 1 30  ? 127.775 128.232 160.845 1.00 43.82  ? 30  THR C CG2 1 
ATOM   7756  N N   . ILE C 1 31  ? 131.528 128.023 158.679 1.00 43.68  ? 31  ILE C N   1 
ATOM   7757  C CA  . ILE C 1 31  ? 132.929 127.758 158.368 1.00 43.68  ? 31  ILE C CA  1 
ATOM   7758  C C   . ILE C 1 31  ? 133.466 126.629 159.239 1.00 43.68  ? 31  ILE C C   1 
ATOM   7759  O O   . ILE C 1 31  ? 134.266 125.800 158.788 1.00 43.68  ? 31  ILE C O   1 
ATOM   7760  C CB  . ILE C 1 31  ? 133.753 129.049 158.535 1.00 43.68  ? 31  ILE C CB  1 
ATOM   7761  C CG1 . ILE C 1 31  ? 133.583 129.958 157.317 1.00 43.68  ? 31  ILE C CG1 1 
ATOM   7762  C CG2 . ILE C 1 31  ? 135.228 128.738 158.777 1.00 43.68  ? 31  ILE C CG2 1 
ATOM   7763  C CD1 . ILE C 1 31  ? 134.034 129.330 156.027 1.00 43.68  ? 31  ILE C CD1 1 
ATOM   7764  N N   . THR C 1 32  ? 133.019 126.564 160.490 1.00 48.10  ? 32  THR C N   1 
ATOM   7765  C CA  . THR C 1 32  ? 133.546 125.636 161.481 1.00 48.10  ? 32  THR C CA  1 
ATOM   7766  C C   . THR C 1 32  ? 132.749 124.340 161.582 1.00 48.10  ? 32  THR C C   1 
ATOM   7767  O O   . THR C 1 32  ? 133.339 123.273 161.774 1.00 48.10  ? 32  THR C O   1 
ATOM   7768  C CB  . THR C 1 32  ? 133.601 126.334 162.847 1.00 48.10  ? 32  THR C CB  1 
ATOM   7769  O OG1 . THR C 1 32  ? 134.788 127.134 162.925 1.00 48.10  ? 32  THR C OG1 1 
ATOM   7770  C CG2 . THR C 1 32  ? 133.588 125.341 163.991 1.00 48.10  ? 32  THR C CG2 1 
ATOM   7771  N N   . ASP C 1 33  ? 131.429 124.393 161.427 1.00 50.33  ? 33  ASP C N   1 
ATOM   7772  C CA  . ASP C 1 33  ? 130.575 123.220 161.563 1.00 50.33  ? 33  ASP C CA  1 
ATOM   7773  C C   . ASP C 1 33  ? 129.788 122.991 160.281 1.00 50.33  ? 33  ASP C C   1 
ATOM   7774  O O   . ASP C 1 33  ? 129.287 123.939 159.671 1.00 50.33  ? 33  ASP C O   1 
ATOM   7775  C CB  . ASP C 1 33  ? 129.606 123.371 162.741 1.00 50.33  ? 33  ASP C CB  1 
ATOM   7776  C CG  . ASP C 1 33  ? 130.239 124.059 163.934 1.00 50.33  ? 33  ASP C CG  1 
ATOM   7777  O OD1 . ASP C 1 33  ? 130.907 123.371 164.736 1.00 50.33  ? 33  ASP C OD1 1 
ATOM   7778  O OD2 . ASP C 1 33  ? 130.068 125.288 164.072 1.00 50.33  ? 33  ASP C OD2 1 
ATOM   7779  N N   . ASP C 1 34  ? 129.678 121.724 159.879 1.00 52.63  ? 34  ASP C N   1 
ATOM   7780  C CA  . ASP C 1 34  ? 128.922 121.390 158.678 1.00 52.63  ? 34  ASP C CA  1 
ATOM   7781  C C   . ASP C 1 34  ? 127.415 121.428 158.909 1.00 52.63  ? 34  ASP C C   1 
ATOM   7782  O O   . ASP C 1 34  ? 126.657 121.648 157.959 1.00 52.63  ? 34  ASP C O   1 
ATOM   7783  C CB  . ASP C 1 34  ? 129.336 120.013 158.159 1.00 52.63  ? 34  ASP C CB  1 
ATOM   7784  C CG  . ASP C 1 34  ? 129.235 118.937 159.217 1.00 52.63  ? 34  ASP C CG  1 
ATOM   7785  O OD1 . ASP C 1 34  ? 129.195 119.283 160.416 1.00 52.63  ? 34  ASP C OD1 1 
ATOM   7786  O OD2 . ASP C 1 34  ? 129.203 117.743 158.851 1.00 52.63  ? 34  ASP C OD2 1 
ATOM   7787  N N   . GLN C 1 35  ? 126.962 121.210 160.143 1.00 52.59  ? 35  GLN C N   1 
ATOM   7788  C CA  . GLN C 1 35  ? 125.538 121.231 160.466 1.00 52.59  ? 35  GLN C CA  1 
ATOM   7789  C C   . GLN C 1 35  ? 125.348 121.828 161.850 1.00 52.59  ? 35  GLN C C   1 
ATOM   7790  O O   . GLN C 1 35  ? 125.849 121.282 162.836 1.00 52.59  ? 35  GLN C O   1 
ATOM   7791  C CB  . GLN C 1 35  ? 124.926 119.826 160.414 1.00 52.59  ? 35  GLN C CB  1 
ATOM   7792  C CG  . GLN C 1 35  ? 124.952 119.157 159.052 1.00 52.59  ? 35  GLN C CG  1 
ATOM   7793  C CD  . GLN C 1 35  ? 123.817 118.170 158.871 1.00 52.59  ? 35  GLN C CD  1 
ATOM   7794  O OE1 . GLN C 1 35  ? 123.455 117.446 159.797 1.00 52.59  ? 35  GLN C OE1 1 
ATOM   7795  N NE2 . GLN C 1 35  ? 123.246 118.137 157.672 1.00 52.59  ? 35  GLN C NE2 1 
ATOM   7796  N N   . ILE C 1 36  ? 124.625 122.942 161.925 1.00 50.87  ? 36  ILE C N   1 
ATOM   7797  C CA  . ILE C 1 36  ? 124.235 123.538 163.197 1.00 50.87  ? 36  ILE C CA  1 
ATOM   7798  C C   . ILE C 1 36  ? 122.779 123.972 163.095 1.00 50.87  ? 36  ILE C C   1 
ATOM   7799  O O   . ILE C 1 36  ? 122.343 124.489 162.062 1.00 50.87  ? 36  ILE C O   1 
ATOM   7800  C CB  . ILE C 1 36  ? 125.159 124.712 163.590 1.00 50.87  ? 36  ILE C CB  1 
ATOM   7801  C CG1 . ILE C 1 36  ? 124.949 125.091 165.055 1.00 50.87  ? 36  ILE C CG1 1 
ATOM   7802  C CG2 . ILE C 1 36  ? 124.962 125.915 162.677 1.00 50.87  ? 36  ILE C CG2 1 
ATOM   7803  C CD1 . ILE C 1 36  ? 126.127 125.811 165.670 1.00 50.87  ? 36  ILE C CD1 1 
ATOM   7804  N N   . GLU C 1 37  ? 122.018 123.738 164.160 1.00 53.47  ? 37  GLU C N   1 
ATOM   7805  C CA  . GLU C 1 37  ? 120.589 124.019 164.176 1.00 53.47  ? 37  GLU C CA  1 
ATOM   7806  C C   . GLU C 1 37  ? 120.332 125.372 164.824 1.00 53.47  ? 37  GLU C C   1 
ATOM   7807  O O   . GLU C 1 37  ? 120.817 125.642 165.926 1.00 53.47  ? 37  GLU C O   1 
ATOM   7808  C CB  . GLU C 1 37  ? 119.825 122.922 164.919 1.00 53.47  ? 37  GLU C CB  1 
ATOM   7809  C CG  . GLU C 1 37  ? 118.337 122.896 164.614 1.00 53.47  ? 37  GLU C CG  1 
ATOM   7810  C CD  . GLU C 1 37  ? 117.562 121.973 165.534 1.00 53.47  ? 37  GLU C CD  1 
ATOM   7811  O OE1 . GLU C 1 37  ? 117.984 120.811 165.708 1.00 53.47  ? 37  GLU C OE1 1 
ATOM   7812  O OE2 . GLU C 1 37  ? 116.532 122.411 166.087 1.00 53.47  ? 37  GLU C OE2 1 
ATOM   7813  N N   . VAL C 1 38  ? 119.561 126.212 164.139 1.00 51.27  ? 38  VAL C N   1 
ATOM   7814  C CA  . VAL C 1 38  ? 119.239 127.552 164.601 1.00 51.27  ? 38  VAL C CA  1 
ATOM   7815  C C   . VAL C 1 38  ? 117.722 127.701 164.642 1.00 51.27  ? 38  VAL C C   1 
ATOM   7816  O O   . VAL C 1 38  ? 116.975 126.856 164.147 1.00 51.27  ? 38  VAL C O   1 
ATOM   7817  C CB  . VAL C 1 38  ? 119.875 128.644 163.719 1.00 51.27  ? 38  VAL C CB  1 
ATOM   7818  C CG1 . VAL C 1 38  ? 121.386 128.516 163.733 1.00 51.27  ? 38  VAL C CG1 1 
ATOM   7819  C CG2 . VAL C 1 38  ? 119.344 128.558 162.301 1.00 51.27  ? 38  VAL C CG2 1 
ATOM   7820  N N   . THR C 1 39  ? 117.275 128.805 165.242 1.00 52.82  ? 39  THR C N   1 
ATOM   7821  C CA  . THR C 1 39  ? 115.853 129.030 165.465 1.00 52.82  ? 39  THR C CA  1 
ATOM   7822  C C   . THR C 1 39  ? 115.125 129.569 164.239 1.00 52.82  ? 39  THR C C   1 
ATOM   7823  O O   . THR C 1 39  ? 113.893 129.496 164.193 1.00 52.82  ? 39  THR C O   1 
ATOM   7824  C CB  . THR C 1 39  ? 115.648 129.995 166.636 1.00 52.82  ? 39  THR C CB  1 
ATOM   7825  O OG1 . THR C 1 39  ? 116.308 131.235 166.360 1.00 52.82  ? 39  THR C OG1 1 
ATOM   7826  C CG2 . THR C 1 39  ? 116.213 129.407 167.916 1.00 52.82  ? 39  THR C CG2 1 
ATOM   7827  N N   . ASN C 1 40  ? 115.843 130.094 163.249 1.00 49.99  ? 40  ASN C N   1 
ATOM   7828  C CA  . ASN C 1 40  ? 115.200 130.717 162.101 1.00 49.99  ? 40  ASN C CA  1 
ATOM   7829  C C   . ASN C 1 40  ? 116.227 130.900 160.992 1.00 49.99  ? 40  ASN C C   1 
ATOM   7830  O O   . ASN C 1 40  ? 117.406 131.144 161.258 1.00 49.99  ? 40  ASN C O   1 
ATOM   7831  C CB  . ASN C 1 40  ? 114.570 132.060 162.494 1.00 49.99  ? 40  ASN C CB  1 
ATOM   7832  C CG  . ASN C 1 40  ? 113.605 132.581 161.455 1.00 49.99  ? 40  ASN C CG  1 
ATOM   7833  O OD1 . ASN C 1 40  ? 113.048 131.821 160.665 1.00 49.99  ? 40  ASN C OD1 1 
ATOM   7834  N ND2 . ASN C 1 40  ? 113.403 133.891 161.453 1.00 49.99  ? 40  ASN C ND2 1 
ATOM   7835  N N   . ALA C 1 41  ? 115.765 130.780 159.747 1.00 43.47  ? 41  ALA C N   1 
ATOM   7836  C CA  . ALA C 1 41  ? 116.644 130.883 158.588 1.00 43.47  ? 41  ALA C CA  1 
ATOM   7837  C C   . ALA C 1 41  ? 115.828 131.290 157.369 1.00 43.47  ? 41  ALA C C   1 
ATOM   7838  O O   . ALA C 1 41  ? 114.604 131.143 157.342 1.00 43.47  ? 41  ALA C O   1 
ATOM   7839  C CB  . ALA C 1 41  ? 117.379 129.565 158.323 1.00 43.47  ? 41  ALA C CB  1 
ATOM   7840  N N   . THR C 1 42  ? 116.529 131.798 156.354 1.00 39.26  ? 42  THR C N   1 
ATOM   7841  C CA  . THR C 1 42  ? 115.908 132.244 155.112 1.00 39.26  ? 42  THR C CA  1 
ATOM   7842  C C   . THR C 1 42  ? 116.612 131.626 153.910 1.00 39.26  ? 42  THR C C   1 
ATOM   7843  O O   . THR C 1 42  ? 117.816 131.359 153.940 1.00 39.26  ? 42  THR C O   1 
ATOM   7844  C CB  . THR C 1 42  ? 115.929 133.777 154.972 1.00 39.26  ? 42  THR C CB  1 
ATOM   7845  O OG1 . THR C 1 42  ? 117.266 134.221 154.713 1.00 39.26  ? 42  THR C OG1 1 
ATOM   7846  C CG2 . THR C 1 42  ? 115.412 134.445 156.231 1.00 39.26  ? 42  THR C CG2 1 
ATOM   7847  N N   . GLU C 1 43  ? 115.846 131.411 152.842 1.00 34.64  ? 43  GLU C N   1 
ATOM   7848  C CA  . GLU C 1 43  ? 116.370 130.846 151.605 1.00 34.64  ? 43  GLU C CA  1 
ATOM   7849  C C   . GLU C 1 43  ? 116.866 131.962 150.694 1.00 34.64  ? 43  GLU C C   1 
ATOM   7850  O O   . GLU C 1 43  ? 116.187 132.977 150.519 1.00 34.64  ? 43  GLU C O   1 
ATOM   7851  C CB  . GLU C 1 43  ? 115.297 130.018 150.897 1.00 34.64  ? 43  GLU C CB  1 
ATOM   7852  C CG  . GLU C 1 43  ? 115.659 129.617 149.480 1.00 34.64  ? 43  GLU C CG  1 
ATOM   7853  C CD  . GLU C 1 43  ? 116.866 128.700 149.424 1.00 34.64  ? 43  GLU C CD  1 
ATOM   7854  O OE1 . GLU C 1 43  ? 116.832 127.627 150.059 1.00 34.64  ? 43  GLU C OE1 1 
ATOM   7855  O OE2 . GLU C 1 43  ? 117.853 129.057 148.750 1.00 34.64  ? 43  GLU C OE2 1 
ATOM   7856  N N   . LEU C 1 44  ? 118.052 131.771 150.113 1.00 32.02  ? 44  LEU C N   1 
ATOM   7857  C CA  . LEU C 1 44  ? 118.687 132.805 149.308 1.00 32.02  ? 44  LEU C CA  1 
ATOM   7858  C C   . LEU C 1 44  ? 118.650 132.550 147.805 1.00 32.02  ? 44  LEU C C   1 
ATOM   7859  O O   . LEU C 1 44  ? 119.035 133.443 147.044 1.00 32.02  ? 44  LEU C O   1 
ATOM   7860  C CB  . LEU C 1 44  ? 120.149 132.992 149.742 1.00 32.02  ? 44  LEU C CB  1 
ATOM   7861  C CG  . LEU C 1 44  ? 120.402 133.621 151.114 1.00 32.02  ? 44  LEU C CG  1 
ATOM   7862  C CD1 . LEU C 1 44  ? 121.879 133.909 151.300 1.00 32.02  ? 44  LEU C CD1 1 
ATOM   7863  C CD2 . LEU C 1 44  ? 119.582 134.888 151.300 1.00 32.02  ? 44  LEU C CD2 1 
ATOM   7864  N N   . VAL C 1 45  ? 118.198 131.383 147.353 1.00 30.13  ? 45  VAL C N   1 
ATOM   7865  C CA  . VAL C 1 45  ? 118.208 131.028 145.936 1.00 30.13  ? 45  VAL C CA  1 
ATOM   7866  C C   . VAL C 1 45  ? 116.770 130.886 145.453 1.00 30.13  ? 45  VAL C C   1 
ATOM   7867  O O   . VAL C 1 45  ? 115.987 130.119 146.025 1.00 30.13  ? 45  VAL C O   1 
ATOM   7868  C CB  . VAL C 1 45  ? 118.999 129.735 145.676 1.00 30.13  ? 45  VAL C CB  1 
ATOM   7869  C CG1 . VAL C 1 45  ? 119.000 129.402 144.190 1.00 30.13  ? 45  VAL C CG1 1 
ATOM   7870  C CG2 . VAL C 1 45  ? 120.420 129.860 146.200 1.00 30.13  ? 45  VAL C CG2 1 
ATOM   7871  N N   . GLN C 1 46  ? 116.428 131.621 144.397 1.00 29.66  ? 46  GLN C N   1 
ATOM   7872  C CA  . GLN C 1 46  ? 115.142 131.461 143.729 1.00 29.66  ? 46  GLN C CA  1 
ATOM   7873  C C   . GLN C 1 46  ? 115.232 130.313 142.731 1.00 29.66  ? 46  GLN C C   1 
ATOM   7874  O O   . GLN C 1 46  ? 116.126 130.291 141.881 1.00 29.66  ? 46  GLN C O   1 
ATOM   7875  C CB  . GLN C 1 46  ? 114.748 132.759 143.024 1.00 29.66  ? 46  GLN C CB  1 
ATOM   7876  C CG  . GLN C 1 46  ? 113.500 132.665 142.166 1.00 29.66  ? 46  GLN C CG  1 
ATOM   7877  C CD  . GLN C 1 46  ? 112.227 132.652 142.986 1.00 29.66  ? 46  GLN C CD  1 
ATOM   7878  O OE1 . GLN C 1 46  ? 112.067 133.439 143.915 1.00 29.66  ? 46  GLN C OE1 1 
ATOM   7879  N NE2 . GLN C 1 46  ? 111.314 131.756 142.644 1.00 29.66  ? 46  GLN C NE2 1 
ATOM   7880  N N   . ASN C 1 47  ? 114.307 129.355 142.829 1.00 30.47  ? 47  ASN C N   1 
ATOM   7881  C CA  . ASN C 1 47  ? 114.431 128.117 142.066 1.00 30.47  ? 47  ASN C CA  1 
ATOM   7882  C C   . ASN C 1 47  ? 113.171 127.757 141.284 1.00 30.47  ? 47  ASN C C   1 
ATOM   7883  O O   . ASN C 1 47  ? 113.043 126.617 140.833 1.00 30.47  ? 47  ASN C O   1 
ATOM   7884  C CB  . ASN C 1 47  ? 114.823 126.959 142.989 1.00 30.47  ? 47  ASN C CB  1 
ATOM   7885  C CG  . ASN C 1 47  ? 113.684 126.509 143.890 1.00 30.47  ? 47  ASN C CG  1 
ATOM   7886  O OD1 . ASN C 1 47  ? 112.735 127.251 144.139 1.00 30.47  ? 47  ASN C OD1 1 
ATOM   7887  N ND2 . ASN C 1 47  ? 113.780 125.286 144.389 1.00 30.47  ? 47  ASN C ND2 1 
ATOM   7888  N N   . SER C 1 48  ? 112.241 128.692 141.100 1.00 32.01  ? 48  SER C N   1 
ATOM   7889  C CA  . SER C 1 48  ? 111.017 128.376 140.379 1.00 32.01  ? 48  SER C CA  1 
ATOM   7890  C C   . SER C 1 48  ? 110.491 129.617 139.674 1.00 32.01  ? 48  SER C C   1 
ATOM   7891  O O   . SER C 1 48  ? 110.840 130.749 140.016 1.00 32.01  ? 48  SER C O   1 
ATOM   7892  C CB  . SER C 1 48  ? 109.943 127.802 141.312 1.00 32.01  ? 48  SER C CB  1 
ATOM   7893  O OG  . SER C 1 48  ? 109.650 128.697 142.370 1.00 32.01  ? 48  SER C OG  1 
ATOM   7894  N N   . SER C 1 49  ? 109.640 129.381 138.677 1.00 34.12  ? 49  SER C N   1 
ATOM   7895  C CA  . SER C 1 49  ? 108.968 130.434 137.933 1.00 34.12  ? 49  SER C CA  1 
ATOM   7896  C C   . SER C 1 49  ? 107.517 130.037 137.709 1.00 34.12  ? 49  SER C C   1 
ATOM   7897  O O   . SER C 1 49  ? 107.179 128.851 137.700 1.00 34.12  ? 49  SER C O   1 
ATOM   7898  C CB  . SER C 1 49  ? 109.650 130.699 136.584 1.00 34.12  ? 49  SER C CB  1 
ATOM   7899  O OG  . SER C 1 49  ? 108.886 131.591 135.794 1.00 34.12  ? 49  SER C OG  1 
ATOM   7900  N N   . THR C 1 50  ? 106.657 131.041 137.531 1.00 37.18  ? 50  THR C N   1 
ATOM   7901  C CA  . THR C 1 50  ? 105.258 130.771 137.219 1.00 37.18  ? 50  THR C CA  1 
ATOM   7902  C C   . THR C 1 50  ? 105.055 130.292 135.788 1.00 37.18  ? 50  THR C C   1 
ATOM   7903  O O   . THR C 1 50  ? 103.955 129.837 135.458 1.00 37.18  ? 50  THR C O   1 
ATOM   7904  C CB  . THR C 1 50  ? 104.402 132.017 137.457 1.00 37.18  ? 50  THR C CB  1 
ATOM   7905  O OG1 . THR C 1 50  ? 104.560 132.926 136.361 1.00 37.18  ? 50  THR C OG1 1 
ATOM   7906  C CG2 . THR C 1 50  ? 104.812 132.708 138.746 1.00 37.18  ? 50  THR C CG2 1 
ATOM   7907  N N   . GLY C 1 51  ? 106.074 130.382 134.938 1.00 35.27  ? 51  GLY C N   1 
ATOM   7908  C CA  . GLY C 1 51  ? 105.953 129.990 133.552 1.00 35.27  ? 51  GLY C CA  1 
ATOM   7909  C C   . GLY C 1 51  ? 105.342 131.026 132.638 1.00 35.27  ? 51  GLY C C   1 
ATOM   7910  O O   . GLY C 1 51  ? 105.049 130.708 131.481 1.00 35.27  ? 51  GLY C O   1 
ATOM   7911  N N   . LYS C 1 52  ? 105.141 132.250 133.114 1.00 36.46  ? 52  LYS C N   1 
ATOM   7912  C CA  . LYS C 1 52  ? 104.509 133.307 132.343 1.00 36.46  ? 52  LYS C CA  1 
ATOM   7913  C C   . LYS C 1 52  ? 105.458 134.490 132.227 1.00 36.46  ? 52  LYS C C   1 
ATOM   7914  O O   . LYS C 1 52  ? 106.249 134.759 133.135 1.00 36.46  ? 52  LYS C O   1 
ATOM   7915  C CB  . LYS C 1 52  ? 103.202 133.767 133.000 1.00 36.46  ? 52  LYS C CB  1 
ATOM   7916  C CG  . LYS C 1 52  ? 102.123 132.704 133.091 1.00 36.46  ? 52  LYS C CG  1 
ATOM   7917  C CD  . LYS C 1 52  ? 101.847 132.067 131.753 1.00 36.46  ? 52  LYS C CD  1 
ATOM   7918  C CE  . LYS C 1 52  ? 100.737 131.034 131.849 1.00 36.46  ? 52  LYS C CE  1 
ATOM   7919  N NZ  . LYS C 1 52  ? 100.298 130.808 133.253 1.00 36.46  ? 52  LYS C NZ  1 
ATOM   7920  N N   . ILE C 1 53  ? 105.375 135.202 131.108 1.00 35.03  ? 53  ILE C N   1 
ATOM   7921  C CA  . ILE C 1 53  ? 106.138 136.427 130.898 1.00 35.03  ? 53  ILE C CA  1 
ATOM   7922  C C   . ILE C 1 53  ? 105.203 137.614 131.083 1.00 35.03  ? 53  ILE C C   1 
ATOM   7923  O O   . ILE C 1 53  ? 104.163 137.704 130.421 1.00 35.03  ? 53  ILE C O   1 
ATOM   7924  C CB  . ILE C 1 53  ? 106.796 136.446 129.508 1.00 35.03  ? 53  ILE C CB  1 
ATOM   7925  C CG1 . ILE C 1 53  ? 107.817 135.312 129.388 1.00 35.03  ? 53  ILE C CG1 1 
ATOM   7926  C CG2 . ILE C 1 53  ? 107.454 137.790 129.243 1.00 35.03  ? 53  ILE C CG2 1 
ATOM   7927  C CD1 . ILE C 1 53  ? 108.400 135.153 128.007 1.00 35.03  ? 53  ILE C CD1 1 
ATOM   7928  N N   . CYS C 1 54  ? 105.566 138.519 131.989 1.00 38.43  ? 54  CYS C N   1 
ATOM   7929  C CA  . CYS C 1 54  ? 104.737 139.677 132.295 1.00 38.43  ? 54  CYS C CA  1 
ATOM   7930  C C   . CYS C 1 54  ? 104.988 140.802 131.300 1.00 38.43  ? 54  CYS C C   1 
ATOM   7931  O O   . CYS C 1 54  ? 106.128 141.053 130.900 1.00 38.43  ? 54  CYS C O   1 
ATOM   7932  C CB  . CYS C 1 54  ? 105.013 140.165 133.718 1.00 38.43  ? 54  CYS C CB  1 
ATOM   7933  S SG  . CYS C 1 54  ? 104.467 139.034 135.021 1.00 38.43  ? 54  CYS C SG  1 
ATOM   7934  N N   . ASN C 1 55  ? 103.917 141.494 130.915 1.00 39.47  ? 55  ASN C N   1 
ATOM   7935  C CA  . ASN C 1 55  ? 103.998 142.542 129.906 1.00 39.47  ? 55  ASN C CA  1 
ATOM   7936  C C   . ASN C 1 55  ? 104.360 143.909 130.476 1.00 39.47  ? 55  ASN C C   1 
ATOM   7937  O O   . ASN C 1 55  ? 104.437 144.877 129.714 1.00 39.47  ? 55  ASN C O   1 
ATOM   7938  C CB  . ASN C 1 55  ? 102.678 142.635 129.126 1.00 39.47  ? 55  ASN C CB  1 
ATOM   7939  C CG  . ASN C 1 55  ? 101.487 142.975 130.007 1.00 39.47  ? 55  ASN C CG  1 
ATOM   7940  O OD1 . ASN C 1 55  ? 101.621 143.179 131.212 1.00 39.47  ? 55  ASN C OD1 1 
ATOM   7941  N ND2 . ASN C 1 55  ? 100.310 143.039 129.400 1.00 39.47  ? 55  ASN C ND2 1 
ATOM   7942  N N   . ASN C 1 56  ? 104.579 144.019 131.781 1.00 38.60  ? 56  ASN C N   1 
ATOM   7943  C CA  . ASN C 1 56  ? 105.012 145.266 132.389 1.00 38.60  ? 56  ASN C CA  1 
ATOM   7944  C C   . ASN C 1 56  ? 106.174 145.006 133.335 1.00 38.60  ? 56  ASN C C   1 
ATOM   7945  O O   . ASN C 1 56  ? 106.250 143.937 133.947 1.00 38.60  ? 56  ASN C O   1 
ATOM   7946  C CB  . ASN C 1 56  ? 103.862 145.938 133.152 1.00 38.60  ? 56  ASN C CB  1 
ATOM   7947  C CG  . ASN C 1 56  ? 103.091 146.915 132.292 1.00 38.60  ? 56  ASN C CG  1 
ATOM   7948  O OD1 . ASN C 1 56  ? 103.643 147.898 131.803 1.00 38.60  ? 56  ASN C OD1 1 
ATOM   7949  N ND2 . ASN C 1 56  ? 101.806 146.648 132.101 1.00 38.60  ? 56  ASN C ND2 1 
ATOM   7950  N N   . PRO C 1 57  ? 107.095 145.973 133.486 1.00 36.23  ? 57  PRO C N   1 
ATOM   7951  C CA  . PRO C 1 57  ? 107.100 147.297 132.855 1.00 36.23  ? 57  PRO C CA  1 
ATOM   7952  C C   . PRO C 1 57  ? 107.783 147.363 131.487 1.00 36.23  ? 57  PRO C C   1 
ATOM   7953  O O   . PRO C 1 57  ? 107.675 148.389 130.822 1.00 36.23  ? 57  PRO C O   1 
ATOM   7954  C CB  . PRO C 1 57  ? 107.870 148.140 133.867 1.00 36.23  ? 57  PRO C CB  1 
ATOM   7955  C CG  . PRO C 1 57  ? 108.870 147.193 134.413 1.00 36.23  ? 57  PRO C CG  1 
ATOM   7956  C CD  . PRO C 1 57  ? 108.209 145.833 134.441 1.00 36.23  ? 57  PRO C CD  1 
ATOM   7957  N N   . HIS C 1 58  ? 108.474 146.304 131.077 1.00 33.43  ? 58  HIS C N   1 
ATOM   7958  C CA  . HIS C 1 58  ? 109.134 146.295 129.780 1.00 33.43  ? 58  HIS C CA  1 
ATOM   7959  C C   . HIS C 1 58  ? 108.120 146.080 128.662 1.00 33.43  ? 58  HIS C C   1 
ATOM   7960  O O   . HIS C 1 58  ? 107.108 145.397 128.837 1.00 33.43  ? 58  HIS C O   1 
ATOM   7961  C CB  . HIS C 1 58  ? 110.203 145.203 129.721 1.00 33.43  ? 58  HIS C CB  1 
ATOM   7962  C CG  . HIS C 1 58  ? 111.147 145.209 130.884 1.00 33.43  ? 58  HIS C CG  1 
ATOM   7963  N ND1 . HIS C 1 58  ? 112.084 146.200 131.078 1.00 33.43  ? 58  HIS C ND1 1 
ATOM   7964  C CD2 . HIS C 1 58  ? 111.307 144.336 131.906 1.00 33.43  ? 58  HIS C CD2 1 
ATOM   7965  C CE1 . HIS C 1 58  ? 112.775 145.941 132.172 1.00 33.43  ? 58  HIS C CE1 1 
ATOM   7966  N NE2 . HIS C 1 58  ? 112.323 144.816 132.694 1.00 33.43  ? 58  HIS C NE2 1 
ATOM   7967  N N   . LYS C 1 59  ? 108.402 146.670 127.503 1.00 30.23  ? 59  LYS C N   1 
ATOM   7968  C CA  . LYS C 1 59  ? 107.573 146.464 126.319 1.00 30.23  ? 59  LYS C CA  1 
ATOM   7969  C C   . LYS C 1 59  ? 108.007 145.171 125.638 1.00 30.23  ? 59  LYS C C   1 
ATOM   7970  O O   . LYS C 1 59  ? 109.100 145.095 125.070 1.00 30.23  ? 59  LYS C O   1 
ATOM   7971  C CB  . LYS C 1 59  ? 107.684 147.652 125.367 1.00 30.23  ? 59  LYS C CB  1 
ATOM   7972  C CG  . LYS C 1 59  ? 106.673 147.623 124.229 1.00 30.23  ? 59  LYS C CG  1 
ATOM   7973  C CD  . LYS C 1 59  ? 106.834 148.820 123.308 1.00 30.23  ? 59  LYS C CD  1 
ATOM   7974  C CE  . LYS C 1 59  ? 105.625 148.993 122.402 1.00 30.23  ? 59  LYS C CE  1 
ATOM   7975  N NZ  . LYS C 1 59  ? 105.400 147.811 121.526 1.00 30.23  ? 59  LYS C NZ  1 
ATOM   7976  N N   . VAL C 1 60  ? 107.149 144.157 125.689 1.00 28.72  ? 60  VAL C N   1 
ATOM   7977  C CA  . VAL C 1 60  ? 107.443 142.835 125.147 1.00 28.72  ? 60  VAL C CA  1 
ATOM   7978  C C   . VAL C 1 60  ? 106.659 142.659 123.855 1.00 28.72  ? 60  VAL C C   1 
ATOM   7979  O O   . VAL C 1 60  ? 105.439 142.855 123.831 1.00 28.72  ? 60  VAL C O   1 
ATOM   7980  C CB  . VAL C 1 60  ? 107.100 141.727 126.158 1.00 28.72  ? 60  VAL C CB  1 
ATOM   7981  C CG1 . VAL C 1 60  ? 107.369 140.357 125.563 1.00 28.72  ? 60  VAL C CG1 1 
ATOM   7982  C CG2 . VAL C 1 60  ? 107.893 141.917 127.441 1.00 28.72  ? 60  VAL C CG2 1 
ATOM   7983  N N   . LEU C 1 61  ? 107.357 142.289 122.785 1.00 28.23  ? 61  LEU C N   1 
ATOM   7984  C CA  . LEU C 1 61  ? 106.751 142.082 121.475 1.00 28.23  ? 61  LEU C CA  1 
ATOM   7985  C C   . LEU C 1 61  ? 106.867 140.613 121.092 1.00 28.23  ? 61  LEU C C   1 
ATOM   7986  O O   . LEU C 1 61  ? 107.975 140.075 121.008 1.00 28.23  ? 61  LEU C O   1 
ATOM   7987  C CB  . LEU C 1 61  ? 107.415 142.968 120.422 1.00 28.23  ? 61  LEU C CB  1 
ATOM   7988  C CG  . LEU C 1 61  ? 106.882 142.867 118.993 1.00 28.23  ? 61  LEU C CG  1 
ATOM   7989  C CD1 . LEU C 1 61  ? 105.428 143.301 118.931 1.00 28.23  ? 61  LEU C CD1 1 
ATOM   7990  C CD2 . LEU C 1 61  ? 107.731 143.697 118.050 1.00 28.23  ? 61  LEU C CD2 1 
ATOM   7991  N N   . ASP C 1 62  ? 105.726 139.975 120.848 1.00 30.53  ? 62  ASP C N   1 
ATOM   7992  C CA  . ASP C 1 62  ? 105.677 138.564 120.483 1.00 30.53  ? 62  ASP C CA  1 
ATOM   7993  C C   . ASP C 1 62  ? 105.851 138.428 118.974 1.00 30.53  ? 62  ASP C C   1 
ATOM   7994  O O   . ASP C 1 62  ? 105.061 138.980 118.201 1.00 30.53  ? 62  ASP C O   1 
ATOM   7995  C CB  . ASP C 1 62  ? 104.356 137.943 120.935 1.00 30.53  ? 62  ASP C CB  1 
ATOM   7996  C CG  . ASP C 1 62  ? 104.332 136.434 120.787 1.00 30.53  ? 62  ASP C CG  1 
ATOM   7997  O OD1 . ASP C 1 62  ? 105.365 135.842 120.420 1.00 30.53  ? 62  ASP C OD1 1 
ATOM   7998  O OD2 . ASP C 1 62  ? 103.272 135.835 121.048 1.00 30.53  ? 62  ASP C OD2 1 
ATOM   7999  N N   . GLY C 1 63  ? 106.882 137.688 118.558 1.00 30.89  ? 63  GLY C N   1 
ATOM   8000  C CA  . GLY C 1 63  ? 107.132 137.482 117.143 1.00 30.89  ? 63  GLY C CA  1 
ATOM   8001  C C   . GLY C 1 63  ? 106.250 136.444 116.485 1.00 30.89  ? 63  GLY C C   1 
ATOM   8002  O O   . GLY C 1 63  ? 106.169 136.415 115.254 1.00 30.89  ? 63  GLY C O   1 
ATOM   8003  N N   . ARG C 1 64  ? 105.592 135.595 117.277 1.00 33.36  ? 64  ARG C N   1 
ATOM   8004  C CA  . ARG C 1 64  ? 104.700 134.550 116.781 1.00 33.36  ? 64  ARG C CA  1 
ATOM   8005  C C   . ARG C 1 64  ? 105.400 133.620 115.796 1.00 33.36  ? 64  ARG C C   1 
ATOM   8006  O O   . ARG C 1 64  ? 106.283 132.851 116.187 1.00 33.36  ? 64  ARG C O   1 
ATOM   8007  C CB  . ARG C 1 64  ? 103.453 135.169 116.148 1.00 33.36  ? 64  ARG C CB  1 
ATOM   8008  C CG  . ARG C 1 64  ? 102.715 136.113 117.078 1.00 33.36  ? 64  ARG C CG  1 
ATOM   8009  C CD  . ARG C 1 64  ? 101.274 136.301 116.655 1.00 33.36  ? 64  ARG C CD  1 
ATOM   8010  N NE  . ARG C 1 64  ? 100.931 137.703 116.450 1.00 33.36  ? 64  ARG C NE  1 
ATOM   8011  C CZ  . ARG C 1 64  ? 100.858 138.293 115.264 1.00 33.36  ? 64  ARG C CZ  1 
ATOM   8012  N NH1 . ARG C 1 64  ? 101.105 137.631 114.145 1.00 33.36  ? 64  ARG C NH1 1 
ATOM   8013  N NH2 . ARG C 1 64  ? 100.519 139.577 115.199 1.00 33.36  ? 64  ARG C NH2 1 
ATOM   8014  N N   . ASP C 1 65  ? 105.022 133.675 114.520 1.00 33.70  ? 65  ASP C N   1 
ATOM   8015  C CA  . ASP C 1 65  ? 105.595 132.799 113.508 1.00 33.70  ? 65  ASP C CA  1 
ATOM   8016  C C   . ASP C 1 65  ? 106.648 133.495 112.649 1.00 33.70  ? 65  ASP C C   1 
ATOM   8017  O O   . ASP C 1 65  ? 107.010 132.978 111.588 1.00 33.70  ? 65  ASP C O   1 
ATOM   8018  C CB  . ASP C 1 65  ? 104.492 132.217 112.624 1.00 33.70  ? 65  ASP C CB  1 
ATOM   8019  C CG  . ASP C 1 65  ? 103.521 133.269 112.135 1.00 33.70  ? 65  ASP C CG  1 
ATOM   8020  O OD1 . ASP C 1 65  ? 103.569 134.409 112.641 1.00 33.70  ? 65  ASP C OD1 1 
ATOM   8021  O OD2 . ASP C 1 65  ? 102.711 132.958 111.240 1.00 33.70  ? 65  ASP C OD2 1 
ATOM   8022  N N   . CYS C 1 66  ? 107.153 134.645 113.088 1.00 31.66  ? 66  CYS C N   1 
ATOM   8023  C CA  . CYS C 1 66  ? 108.132 135.421 112.339 1.00 31.66  ? 66  CYS C CA  1 
ATOM   8024  C C   . CYS C 1 66  ? 109.416 135.588 113.140 1.00 31.66  ? 66  CYS C C   1 
ATOM   8025  O O   . CYS C 1 66  ? 109.376 135.877 114.339 1.00 31.66  ? 66  CYS C O   1 
ATOM   8026  C CB  . CYS C 1 66  ? 107.578 136.805 111.978 1.00 31.66  ? 66  CYS C CB  1 
ATOM   8027  S SG  . CYS C 1 66  ? 106.263 136.811 110.744 1.00 31.66  ? 66  CYS C SG  1 
ATOM   8028  N N   . THR C 1 67  ? 110.554 135.415 112.472 1.00 27.95  ? 67  THR C N   1 
ATOM   8029  C CA  . THR C 1 67  ? 111.830 135.804 113.050 1.00 27.95  ? 67  THR C CA  1 
ATOM   8030  C C   . THR C 1 67  ? 112.055 137.302 112.854 1.00 27.95  ? 67  THR C C   1 
ATOM   8031  O O   . THR C 1 67  ? 111.350 137.968 112.093 1.00 27.95  ? 67  THR C O   1 
ATOM   8032  C CB  . THR C 1 67  ? 112.980 135.009 112.429 1.00 27.95  ? 67  THR C CB  1 
ATOM   8033  O OG1 . THR C 1 67  ? 113.069 135.299 111.030 1.00 27.95  ? 67  THR C OG1 1 
ATOM   8034  C CG2 . THR C 1 67  ? 112.766 133.518 112.619 1.00 27.95  ? 67  THR C CG2 1 
ATOM   8035  N N   . LEU C 1 68  ? 113.050 137.839 113.562 1.00 25.77  ? 68  LEU C N   1 
ATOM   8036  C CA  . LEU C 1 68  ? 113.339 139.267 113.454 1.00 25.77  ? 68  LEU C CA  1 
ATOM   8037  C C   . LEU C 1 68  ? 113.826 139.636 112.054 1.00 25.77  ? 68  LEU C C   1 
ATOM   8038  O O   . LEU C 1 68  ? 113.423 140.669 111.506 1.00 25.77  ? 68  LEU C O   1 
ATOM   8039  C CB  . LEU C 1 68  ? 114.363 139.680 114.512 1.00 25.77  ? 68  LEU C CB  1 
ATOM   8040  C CG  . LEU C 1 68  ? 114.690 141.175 114.560 1.00 25.77  ? 68  LEU C CG  1 
ATOM   8041  C CD1 . LEU C 1 68  ? 113.432 141.996 114.800 1.00 25.77  ? 68  LEU C CD1 1 
ATOM   8042  C CD2 . LEU C 1 68  ? 115.742 141.479 115.612 1.00 25.77  ? 68  LEU C CD2 1 
ATOM   8043  N N   . ILE C 1 69  ? 114.682 138.804 111.456 1.00 25.09  ? 69  ILE C N   1 
ATOM   8044  C CA  . ILE C 1 69  ? 115.210 139.104 110.127 1.00 25.09  ? 69  ILE C CA  1 
ATOM   8045  C C   . ILE C 1 69  ? 114.099 139.077 109.082 1.00 25.09  ? 69  ILE C C   1 
ATOM   8046  O O   . ILE C 1 69  ? 114.054 139.927 108.186 1.00 25.09  ? 69  ILE C O   1 
ATOM   8047  C CB  . ILE C 1 69  ? 116.352 138.132 109.773 1.00 25.09  ? 69  ILE C CB  1 
ATOM   8048  C CG1 . ILE C 1 69  ? 117.520 138.304 110.746 1.00 25.09  ? 69  ILE C CG1 1 
ATOM   8049  C CG2 . ILE C 1 69  ? 116.820 138.343 108.341 1.00 25.09  ? 69  ILE C CG2 1 
ATOM   8050  C CD1 . ILE C 1 69  ? 118.263 139.604 110.586 1.00 25.09  ? 69  ILE C CD1 1 
ATOM   8051  N N   . ASP C 1 70  ? 113.192 138.103 109.173 1.00 27.08  ? 70  ASP C N   1 
ATOM   8052  C CA  . ASP C 1 70  ? 112.097 138.023 108.211 1.00 27.08  ? 70  ASP C CA  1 
ATOM   8053  C C   . ASP C 1 70  ? 111.152 139.212 108.341 1.00 27.08  ? 70  ASP C C   1 
ATOM   8054  O O   . ASP C 1 70  ? 110.611 139.692 107.340 1.00 27.08  ? 70  ASP C O   1 
ATOM   8055  C CB  . ASP C 1 70  ? 111.338 136.709 108.387 1.00 27.08  ? 70  ASP C CB  1 
ATOM   8056  C CG  . ASP C 1 70  ? 111.953 135.576 107.599 1.00 27.08  ? 70  ASP C CG  1 
ATOM   8057  O OD1 . ASP C 1 70  ? 112.484 135.836 106.501 1.00 27.08  ? 70  ASP C OD1 1 
ATOM   8058  O OD2 . ASP C 1 70  ? 111.911 134.424 108.075 1.00 27.08  ? 70  ASP C OD2 1 
ATOM   8059  N N   . ALA C 1 71  ? 110.930 139.691 109.566 1.00 25.96  ? 71  ALA C N   1 
ATOM   8060  C CA  . ALA C 1 71  ? 110.121 140.891 109.752 1.00 25.96  ? 71  ALA C CA  1 
ATOM   8061  C C   . ALA C 1 71  ? 110.833 142.125 109.211 1.00 25.96  ? 71  ALA C C   1 
ATOM   8062  O O   . ALA C 1 71  ? 110.190 143.029 108.667 1.00 25.96  ? 71  ALA C O   1 
ATOM   8063  C CB  . ALA C 1 71  ? 109.773 141.072 111.229 1.00 25.96  ? 71  ALA C CB  1 
ATOM   8064  N N   . MET C 1 72  ? 112.157 142.189 109.364 1.00 26.12  ? 72  MET C N   1 
ATOM   8065  C CA  . MET C 1 72  ? 112.912 143.313 108.818 1.00 26.12  ? 72  MET C CA  1 
ATOM   8066  C C   . MET C 1 72  ? 112.871 143.332 107.292 1.00 26.12  ? 72  MET C C   1 
ATOM   8067  O O   . MET C 1 72  ? 112.674 144.392 106.688 1.00 26.12  ? 72  MET C O   1 
ATOM   8068  C CB  . MET C 1 72  ? 114.356 143.265 109.314 1.00 26.12  ? 72  MET C CB  1 
ATOM   8069  C CG  . MET C 1 72  ? 115.208 144.437 108.858 1.00 26.12  ? 72  MET C CG  1 
ATOM   8070  S SD  . MET C 1 72  ? 116.267 144.035 107.458 1.00 26.12  ? 72  MET C SD  1 
ATOM   8071  C CE  . MET C 1 72  ? 117.300 142.759 108.170 1.00 26.12  ? 72  MET C CE  1 
ATOM   8072  N N   . LEU C 1 73  ? 113.050 142.172 106.652 1.00 24.97  ? 73  LEU C N   1 
ATOM   8073  C CA  . LEU C 1 73  ? 113.118 142.133 105.193 1.00 24.97  ? 73  LEU C CA  1 
ATOM   8074  C C   . LEU C 1 73  ? 111.764 142.403 104.550 1.00 24.97  ? 73  LEU C C   1 
ATOM   8075  O O   . LEU C 1 73  ? 111.702 143.012 103.478 1.00 24.97  ? 73  LEU C O   1 
ATOM   8076  C CB  . LEU C 1 73  ? 113.665 140.787 104.716 1.00 24.97  ? 73  LEU C CB  1 
ATOM   8077  C CG  . LEU C 1 73  ? 115.101 140.400 105.085 1.00 24.97  ? 73  LEU C CG  1 
ATOM   8078  C CD1 . LEU C 1 73  ? 115.420 138.999 104.590 1.00 24.97  ? 73  LEU C CD1 1 
ATOM   8079  C CD2 . LEU C 1 73  ? 116.104 141.402 104.536 1.00 24.97  ? 73  LEU C CD2 1 
ATOM   8080  N N   . GLY C 1 74  ? 110.678 141.955 105.170 1.00 26.85  ? 74  GLY C N   1 
ATOM   8081  C CA  . GLY C 1 74  ? 109.361 142.177 104.610 1.00 26.85  ? 74  GLY C CA  1 
ATOM   8082  C C   . GLY C 1 74  ? 108.711 140.940 104.026 1.00 26.85  ? 74  GLY C C   1 
ATOM   8083  O O   . GLY C 1 74  ? 108.050 141.016 102.987 1.00 26.85  ? 74  GLY C O   1 
ATOM   8084  N N   . ASP C 1 75  ? 108.901 139.799 104.681 1.00 30.48  ? 75  ASP C N   1 
ATOM   8085  C CA  . ASP C 1 75  ? 108.166 138.593 104.329 1.00 30.48  ? 75  ASP C CA  1 
ATOM   8086  C C   . ASP C 1 75  ? 106.670 138.873 104.449 1.00 30.48  ? 75  ASP C C   1 
ATOM   8087  O O   . ASP C 1 75  ? 106.233 139.425 105.466 1.00 30.48  ? 75  ASP C O   1 
ATOM   8088  C CB  . ASP C 1 75  ? 108.578 137.441 105.249 1.00 30.48  ? 75  ASP C CB  1 
ATOM   8089  C CG  . ASP C 1 75  ? 108.149 136.078 104.730 1.00 30.48  ? 75  ASP C CG  1 
ATOM   8090  O OD1 . ASP C 1 75  ? 106.944 135.867 104.496 1.00 30.48  ? 75  ASP C OD1 1 
ATOM   8091  O OD2 . ASP C 1 75  ? 109.022 135.203 104.576 1.00 30.48  ? 75  ASP C OD2 1 
ATOM   8092  N N   . PRO C 1 76  ? 105.863 138.533 103.439 1.00 32.16  ? 76  PRO C N   1 
ATOM   8093  C CA  . PRO C 1 76  ? 104.448 138.951 103.451 1.00 32.16  ? 76  PRO C CA  1 
ATOM   8094  C C   . PRO C 1 76  ? 103.674 138.542 104.695 1.00 32.16  ? 76  PRO C C   1 
ATOM   8095  O O   . PRO C 1 76  ? 102.944 139.370 105.256 1.00 32.16  ? 76  PRO C O   1 
ATOM   8096  C CB  . PRO C 1 76  ? 103.887 138.279 102.191 1.00 32.16  ? 76  PRO C CB  1 
ATOM   8097  C CG  . PRO C 1 76  ? 105.051 138.160 101.287 1.00 32.16  ? 76  PRO C CG  1 
ATOM   8098  C CD  . PRO C 1 76  ? 106.241 137.897 102.166 1.00 32.16  ? 76  PRO C CD  1 
ATOM   8099  N N   . HIS C 1 77  ? 103.843 137.310 105.175 1.00 31.88  ? 77  HIS C N   1 
ATOM   8100  C CA  . HIS C 1 77  ? 103.131 136.898 106.380 1.00 31.88  ? 77  HIS C CA  1 
ATOM   8101  C C   . HIS C 1 77  ? 103.667 137.571 107.639 1.00 31.88  ? 77  HIS C C   1 
ATOM   8102  O O   . HIS C 1 77  ? 103.129 137.334 108.724 1.00 31.88  ? 77  HIS C O   1 
ATOM   8103  C CB  . HIS C 1 77  ? 103.165 135.371 106.515 1.00 31.88  ? 77  HIS C CB  1 
ATOM   8104  C CG  . HIS C 1 77  ? 104.364 134.841 107.237 1.00 31.88  ? 77  HIS C CG  1 
ATOM   8105  N ND1 . HIS C 1 77  ? 105.598 134.714 106.638 1.00 31.88  ? 77  HIS C ND1 1 
ATOM   8106  C CD2 . HIS C 1 77  ? 104.511 134.377 108.500 1.00 31.88  ? 77  HIS C CD2 1 
ATOM   8107  C CE1 . HIS C 1 77  ? 106.457 134.210 107.506 1.00 31.88  ? 77  HIS C CE1 1 
ATOM   8108  N NE2 . HIS C 1 77  ? 105.822 133.995 108.643 1.00 31.88  ? 77  HIS C NE2 1 
ATOM   8109  N N   . CYS C 1 78  ? 104.700 138.404 107.516 1.00 32.66  ? 78  CYS C N   1 
ATOM   8110  C CA  . CYS C 1 78  ? 105.201 139.229 108.606 1.00 32.66  ? 78  CYS C CA  1 
ATOM   8111  C C   . CYS C 1 78  ? 104.873 140.705 108.412 1.00 32.66  ? 78  CYS C C   1 
ATOM   8112  O O   . CYS C 1 78  ? 105.399 141.551 109.146 1.00 32.66  ? 78  CYS C O   1 
ATOM   8113  C CB  . CYS C 1 78  ? 106.713 139.040 108.753 1.00 32.66  ? 78  CYS C CB  1 
ATOM   8114  S SG  . CYS C 1 78  ? 107.216 137.332 109.026 1.00 32.66  ? 78  CYS C SG  1 
ATOM   8115  N N   . ASP C 1 79  ? 103.995 141.033 107.456 1.00 33.68  ? 79  ASP C N   1 
ATOM   8116  C CA  . ASP C 1 79  ? 103.714 142.429 107.134 1.00 33.68  ? 79  ASP C CA  1 
ATOM   8117  C C   . ASP C 1 79  ? 103.136 143.202 108.312 1.00 33.68  ? 79  ASP C C   1 
ATOM   8118  O O   . ASP C 1 79  ? 103.179 144.436 108.309 1.00 33.68  ? 79  ASP C O   1 
ATOM   8119  C CB  . ASP C 1 79  ? 102.753 142.515 105.948 1.00 33.68  ? 79  ASP C CB  1 
ATOM   8120  C CG  . ASP C 1 79  ? 103.451 142.339 104.613 1.00 33.68  ? 79  ASP C CG  1 
ATOM   8121  O OD1 . ASP C 1 79  ? 104.686 142.512 104.550 1.00 33.68  ? 79  ASP C OD1 1 
ATOM   8122  O OD2 . ASP C 1 79  ? 102.757 142.025 103.623 1.00 33.68  ? 79  ASP C OD2 1 
ATOM   8123  N N   . VAL C 1 80  ? 102.595 142.510 109.316 1.00 32.70  ? 80  VAL C N   1 
ATOM   8124  C CA  . VAL C 1 80  ? 102.048 143.178 110.491 1.00 32.70  ? 80  VAL C CA  1 
ATOM   8125  C C   . VAL C 1 80  ? 103.123 143.787 111.381 1.00 32.70  ? 80  VAL C C   1 
ATOM   8126  O O   . VAL C 1 80  ? 102.798 144.572 112.276 1.00 32.70  ? 80  VAL C O   1 
ATOM   8127  C CB  . VAL C 1 80  ? 101.181 142.181 111.291 1.00 32.70  ? 80  VAL C CB  1 
ATOM   8128  C CG1 . VAL C 1 80  ? 102.054 141.243 112.109 1.00 32.70  ? 80  VAL C CG1 1 
ATOM   8129  C CG2 . VAL C 1 80  ? 100.179 142.910 112.173 1.00 32.70  ? 80  VAL C CG2 1 
ATOM   8130  N N   . PHE C 1 81  ? 104.397 143.470 111.154 1.00 31.48  ? 81  PHE C N   1 
ATOM   8131  C CA  . PHE C 1 81  ? 105.473 143.932 112.022 1.00 31.48  ? 81  PHE C CA  1 
ATOM   8132  C C   . PHE C 1 81  ? 106.151 145.203 111.520 1.00 31.48  ? 81  PHE C C   1 
ATOM   8133  O O   . PHE C 1 81  ? 107.221 145.555 112.022 1.00 31.48  ? 81  PHE C O   1 
ATOM   8134  C CB  . PHE C 1 81  ? 106.518 142.828 112.201 1.00 31.48  ? 81  PHE C CB  1 
ATOM   8135  C CG  . PHE C 1 81  ? 106.077 141.721 113.108 1.00 31.48  ? 81  PHE C CG  1 
ATOM   8136  C CD1 . PHE C 1 81  ? 106.164 141.860 114.482 1.00 31.48  ? 81  PHE C CD1 1 
ATOM   8137  C CD2 . PHE C 1 81  ? 105.573 140.540 112.589 1.00 31.48  ? 81  PHE C CD2 1 
ATOM   8138  C CE1 . PHE C 1 81  ? 105.757 140.843 115.321 1.00 31.48  ? 81  PHE C CE1 1 
ATOM   8139  C CE2 . PHE C 1 81  ? 105.166 139.521 113.423 1.00 31.48  ? 81  PHE C CE2 1 
ATOM   8140  C CZ  . PHE C 1 81  ? 105.257 139.672 114.790 1.00 31.48  ? 81  PHE C CZ  1 
ATOM   8141  N N   . GLN C 1 82  ? 105.560 145.897 110.552 1.00 32.64  ? 82  GLN C N   1 
ATOM   8142  C CA  . GLN C 1 82  ? 106.202 147.074 109.981 1.00 32.64  ? 82  GLN C CA  1 
ATOM   8143  C C   . GLN C 1 82  ? 106.235 148.221 110.986 1.00 32.64  ? 82  GLN C C   1 
ATOM   8144  O O   . GLN C 1 82  ? 105.213 148.563 111.587 1.00 32.64  ? 82  GLN C O   1 
ATOM   8145  C CB  . GLN C 1 82  ? 105.476 147.507 108.708 1.00 32.64  ? 82  GLN C CB  1 
ATOM   8146  C CG  . GLN C 1 82  ? 105.798 146.648 107.497 1.00 32.64  ? 82  GLN C CG  1 
ATOM   8147  C CD  . GLN C 1 82  ? 105.105 147.128 106.241 1.00 32.64  ? 82  GLN C CD  1 
ATOM   8148  O OE1 . GLN C 1 82  ? 104.198 147.957 106.297 1.00 32.64  ? 82  GLN C OE1 1 
ATOM   8149  N NE2 . GLN C 1 82  ? 105.525 146.605 105.097 1.00 32.64  ? 82  GLN C NE2 1 
ATOM   8150  N N   . ASP C 1 83  ? 107.421 148.809 111.162 1.00 33.83  ? 83  ASP C N   1 
ATOM   8151  C CA  . ASP C 1 83  ? 107.617 150.002 111.991 1.00 33.83  ? 83  ASP C CA  1 
ATOM   8152  C C   . ASP C 1 83  ? 107.287 149.741 113.462 1.00 33.83  ? 83  ASP C C   1 
ATOM   8153  O O   . ASP C 1 83  ? 106.728 150.595 114.150 1.00 33.83  ? 83  ASP C O   1 
ATOM   8154  C CB  . ASP C 1 83  ? 106.805 151.183 111.454 1.00 33.83  ? 83  ASP C CB  1 
ATOM   8155  C CG  . ASP C 1 83  ? 107.337 151.704 110.132 1.00 33.83  ? 83  ASP C CG  1 
ATOM   8156  O OD1 . ASP C 1 83  ? 108.520 151.457 109.823 1.00 33.83  ? 83  ASP C OD1 1 
ATOM   8157  O OD2 . ASP C 1 83  ? 106.570 152.357 109.397 1.00 33.83  ? 83  ASP C OD2 1 
ATOM   8158  N N   . GLU C 1 84  ? 107.643 148.559 113.952 1.00 32.77  ? 84  GLU C N   1 
ATOM   8159  C CA  . GLU C 1 84  ? 107.419 148.205 115.346 1.00 32.77  ? 84  GLU C CA  1 
ATOM   8160  C C   . GLU C 1 84  ? 108.602 148.625 116.216 1.00 32.77  ? 84  GLU C C   1 
ATOM   8161  O O   . GLU C 1 84  ? 109.702 148.888 115.728 1.00 32.77  ? 84  GLU C O   1 
ATOM   8162  C CB  . GLU C 1 84  ? 107.176 146.702 115.488 1.00 32.77  ? 84  GLU C CB  1 
ATOM   8163  C CG  . GLU C 1 84  ? 105.740 146.275 115.251 1.00 32.77  ? 84  GLU C CG  1 
ATOM   8164  C CD  . GLU C 1 84  ? 104.881 146.385 116.495 1.00 32.77  ? 84  GLU C CD  1 
ATOM   8165  O OE1 . GLU C 1 84  ? 105.332 147.003 117.480 1.00 32.77  ? 84  GLU C OE1 1 
ATOM   8166  O OE2 . GLU C 1 84  ? 103.751 145.854 116.486 1.00 32.77  ? 84  GLU C OE2 1 
ATOM   8167  N N   . LYS C 1 85  ? 108.357 148.681 117.525 1.00 31.28  ? 85  LYS C N   1 
ATOM   8168  C CA  . LYS C 1 85  ? 109.391 148.967 118.511 1.00 31.28  ? 85  LYS C CA  1 
ATOM   8169  C C   . LYS C 1 85  ? 109.225 148.018 119.691 1.00 31.28  ? 85  LYS C C   1 
ATOM   8170  O O   . LYS C 1 85  ? 108.145 147.473 119.923 1.00 31.28  ? 85  LYS C O   1 
ATOM   8171  C CB  . LYS C 1 85  ? 109.340 150.425 118.986 1.00 31.28  ? 85  LYS C CB  1 
ATOM   8172  C CG  . LYS C 1 85  ? 107.949 150.916 119.353 1.00 31.28  ? 85  LYS C CG  1 
ATOM   8173  C CD  . LYS C 1 85  ? 108.011 152.209 120.155 1.00 31.28  ? 85  LYS C CD  1 
ATOM   8174  C CE  . LYS C 1 85  ? 106.933 152.258 121.230 1.00 31.28  ? 85  LYS C CE  1 
ATOM   8175  N NZ  . LYS C 1 85  ? 105.559 152.149 120.666 1.00 31.28  ? 85  LYS C NZ  1 
ATOM   8176  N N   . TRP C 1 86  ? 110.310 147.822 120.439 1.00 26.43  ? 86  TRP C N   1 
ATOM   8177  C CA  . TRP C 1 86  ? 110.292 146.861 121.533 1.00 26.43  ? 86  TRP C CA  1 
ATOM   8178  C C   . TRP C 1 86  ? 111.388 147.185 122.535 1.00 26.43  ? 86  TRP C C   1 
ATOM   8179  O O   . TRP C 1 86  ? 112.353 147.888 122.229 1.00 26.43  ? 86  TRP C O   1 
ATOM   8180  C CB  . TRP C 1 86  ? 110.471 145.427 121.019 1.00 26.43  ? 86  TRP C CB  1 
ATOM   8181  C CG  . TRP C 1 86  ? 111.769 145.220 120.299 1.00 26.43  ? 86  TRP C CG  1 
ATOM   8182  C CD1 . TRP C 1 86  ? 112.945 144.791 120.836 1.00 26.43  ? 86  TRP C CD1 1 
ATOM   8183  C CD2 . TRP C 1 86  ? 112.021 145.438 118.907 1.00 26.43  ? 86  TRP C CD2 1 
ATOM   8184  N NE1 . TRP C 1 86  ? 113.913 144.729 119.868 1.00 26.43  ? 86  TRP C NE1 1 
ATOM   8185  C CE2 . TRP C 1 86  ? 113.372 145.123 118.674 1.00 26.43  ? 86  TRP C CE2 1 
ATOM   8186  C CE3 . TRP C 1 86  ? 111.236 145.872 117.835 1.00 26.43  ? 86  TRP C CE3 1 
ATOM   8187  C CZ2 . TRP C 1 86  ? 113.954 145.224 117.413 1.00 26.43  ? 86  TRP C CZ2 1 
ATOM   8188  C CZ3 . TRP C 1 86  ? 111.816 145.974 116.586 1.00 26.43  ? 86  TRP C CZ3 1 
ATOM   8189  C CH2 . TRP C 1 86  ? 113.162 145.651 116.386 1.00 26.43  ? 86  TRP C CH2 1 
ATOM   8190  N N   . ASP C 1 87  ? 111.215 146.658 123.746 1.00 28.76  ? 87  ASP C N   1 
ATOM   8191  C CA  . ASP C 1 87  ? 112.299 146.488 124.705 1.00 28.76  ? 87  ASP C CA  1 
ATOM   8192  C C   . ASP C 1 87  ? 112.871 145.079 124.667 1.00 28.76  ? 87  ASP C C   1 
ATOM   8193  O O   . ASP C 1 87  ? 114.086 144.903 124.785 1.00 28.76  ? 87  ASP C O   1 
ATOM   8194  C CB  . ASP C 1 87  ? 111.823 146.804 126.128 1.00 28.76  ? 87  ASP C CB  1 
ATOM   8195  C CG  . ASP C 1 87  ? 111.622 148.287 126.366 1.00 28.76  ? 87  ASP C CG  1 
ATOM   8196  O OD1 . ASP C 1 87  ? 112.384 149.095 125.800 1.00 28.76  ? 87  ASP C OD1 1 
ATOM   8197  O OD2 . ASP C 1 87  ? 110.699 148.646 127.124 1.00 28.76  ? 87  ASP C OD2 1 
ATOM   8198  N N   . LEU C 1 88  ? 112.015 144.073 124.496 1.00 26.42  ? 88  LEU C N   1 
ATOM   8199  C CA  . LEU C 1 88  ? 112.439 142.686 124.345 1.00 26.42  ? 88  LEU C CA  1 
ATOM   8200  C C   . LEU C 1 88  ? 111.626 142.042 123.232 1.00 26.42  ? 88  LEU C C   1 
ATOM   8201  O O   . LEU C 1 88  ? 110.394 142.032 123.286 1.00 26.42  ? 88  LEU C O   1 
ATOM   8202  C CB  . LEU C 1 88  ? 112.271 141.904 125.653 1.00 26.42  ? 88  LEU C CB  1 
ATOM   8203  C CG  . LEU C 1 88  ? 112.752 140.450 125.634 1.00 26.42  ? 88  LEU C CG  1 
ATOM   8204  C CD1 . LEU C 1 88  ? 114.271 140.370 125.556 1.00 26.42  ? 88  LEU C CD1 1 
ATOM   8205  C CD2 . LEU C 1 88  ? 112.233 139.689 126.843 1.00 26.42  ? 88  LEU C CD2 1 
ATOM   8206  N N   . PHE C 1 89  ? 112.316 141.513 122.228 1.00 25.70  ? 89  PHE C N   1 
ATOM   8207  C CA  . PHE C 1 89  ? 111.697 140.762 121.144 1.00 25.70  ? 89  PHE C CA  1 
ATOM   8208  C C   . PHE C 1 89  ? 111.792 139.275 121.466 1.00 25.70  ? 89  PHE C C   1 
ATOM   8209  O O   . PHE C 1 89  ? 112.882 138.766 121.741 1.00 25.70  ? 89  PHE C O   1 
ATOM   8210  C CB  . PHE C 1 89  ? 112.388 141.079 119.814 1.00 25.70  ? 89  PHE C CB  1 
ATOM   8211  C CG  . PHE C 1 89  ? 111.675 140.542 118.603 1.00 25.70  ? 89  PHE C CG  1 
ATOM   8212  C CD1 . PHE C 1 89  ? 111.854 139.231 118.197 1.00 25.70  ? 89  PHE C CD1 1 
ATOM   8213  C CD2 . PHE C 1 89  ? 110.841 141.357 117.858 1.00 25.70  ? 89  PHE C CD2 1 
ATOM   8214  C CE1 . PHE C 1 89  ? 111.204 138.740 117.086 1.00 25.70  ? 89  PHE C CE1 1 
ATOM   8215  C CE2 . PHE C 1 89  ? 110.190 140.870 116.744 1.00 25.70  ? 89  PHE C CE2 1 
ATOM   8216  C CZ  . PHE C 1 89  ? 110.371 139.561 116.358 1.00 25.70  ? 89  PHE C CZ  1 
ATOM   8217  N N   . VAL C 1 90  ? 110.655 138.583 121.434 1.00 26.38  ? 90  VAL C N   1 
ATOM   8218  C CA  . VAL C 1 90  ? 110.580 137.168 121.786 1.00 26.38  ? 90  VAL C CA  1 
ATOM   8219  C C   . VAL C 1 90  ? 110.367 136.357 120.514 1.00 26.38  ? 90  VAL C C   1 
ATOM   8220  O O   . VAL C 1 90  ? 109.333 136.492 119.850 1.00 26.38  ? 90  VAL C O   1 
ATOM   8221  C CB  . VAL C 1 90  ? 109.462 136.896 122.806 1.00 26.38  ? 90  VAL C CB  1 
ATOM   8222  C CG1 . VAL C 1 90  ? 109.420 135.419 123.170 1.00 26.38  ? 90  VAL C CG1 1 
ATOM   8223  C CG2 . VAL C 1 90  ? 109.657 137.744 124.049 1.00 26.38  ? 90  VAL C CG2 1 
ATOM   8224  N N   . GLU C 1 91  ? 111.334 135.503 120.187 1.00 28.88  ? 91  GLU C N   1 
ATOM   8225  C CA  . GLU C 1 91  ? 111.266 134.631 119.020 1.00 28.88  ? 91  GLU C CA  1 
ATOM   8226  C C   . GLU C 1 91  ? 110.759 133.254 119.431 1.00 28.88  ? 91  GLU C C   1 
ATOM   8227  O O   . GLU C 1 91  ? 111.287 132.647 120.367 1.00 28.88  ? 91  GLU C O   1 
ATOM   8228  C CB  . GLU C 1 91  ? 112.637 134.503 118.353 1.00 28.88  ? 91  GLU C CB  1 
ATOM   8229  C CG  . GLU C 1 91  ? 112.909 135.521 117.262 1.00 28.88  ? 91  GLU C CG  1 
ATOM   8230  C CD  . GLU C 1 91  ? 114.270 135.334 116.617 1.00 28.88  ? 91  GLU C CD  1 
ATOM   8231  O OE1 . GLU C 1 91  ? 115.064 134.520 117.128 1.00 28.88  ? 91  GLU C OE1 1 
ATOM   8232  O OE2 . GLU C 1 91  ? 114.547 136.000 115.600 1.00 28.88  ? 91  GLU C OE2 1 
ATOM   8233  N N   . ARG C 1 92  ? 109.748 132.762 118.724 1.00 29.58  ? 92  ARG C N   1 
ATOM   8234  C CA  . ARG C 1 92  ? 109.170 131.455 119.000 1.00 29.58  ? 92  ARG C CA  1 
ATOM   8235  C C   . ARG C 1 92  ? 109.836 130.379 118.150 1.00 29.58  ? 92  ARG C C   1 
ATOM   8236  O O   . ARG C 1 92  ? 110.449 130.655 117.117 1.00 29.58  ? 92  ARG C O   1 
ATOM   8237  C CB  . ARG C 1 92  ? 107.663 131.464 118.745 1.00 29.58  ? 92  ARG C CB  1 
ATOM   8238  C CG  . ARG C 1 92  ? 106.923 132.615 119.398 1.00 29.58  ? 92  ARG C CG  1 
ATOM   8239  C CD  . ARG C 1 92  ? 107.133 132.620 120.897 1.00 29.58  ? 92  ARG C CD  1 
ATOM   8240  N NE  . ARG C 1 92  ? 106.110 133.388 121.596 1.00 29.58  ? 92  ARG C NE  1 
ATOM   8241  C CZ  . ARG C 1 92  ? 105.986 133.443 122.914 1.00 29.58  ? 92  ARG C CZ  1 
ATOM   8242  N NH1 . ARG C 1 92  ? 106.815 132.793 123.713 1.00 29.58  ? 92  ARG C NH1 1 
ATOM   8243  N NH2 . ARG C 1 92  ? 105.005 134.165 123.444 1.00 29.58  ? 92  ARG C NH2 1 
ATOM   8244  N N   . SER C 1 93  ? 109.706 129.132 118.602 1.00 32.30  ? 93  SER C N   1 
ATOM   8245  C CA  . SER C 1 93  ? 110.311 128.003 117.907 1.00 32.30  ? 93  SER C CA  1 
ATOM   8246  C C   . SER C 1 93  ? 109.473 127.500 116.739 1.00 32.30  ? 93  SER C C   1 
ATOM   8247  O O   . SER C 1 93  ? 109.957 126.666 115.968 1.00 32.30  ? 93  SER C O   1 
ATOM   8248  C CB  . SER C 1 93  ? 110.569 126.857 118.890 1.00 32.30  ? 93  SER C CB  1 
ATOM   8249  O OG  . SER C 1 93  ? 109.402 126.087 119.103 1.00 32.30  ? 93  SER C OG  1 
ATOM   8250  N N   . SER C 1 94  ? 108.243 127.981 116.585 1.00 31.92  ? 94  SER C N   1 
ATOM   8251  C CA  . SER C 1 94  ? 107.392 127.612 115.462 1.00 31.92  ? 94  SER C CA  1 
ATOM   8252  C C   . SER C 1 94  ? 107.496 128.592 114.297 1.00 31.92  ? 94  SER C C   1 
ATOM   8253  O O   . SER C 1 94  ? 106.715 128.489 113.347 1.00 31.92  ? 94  SER C O   1 
ATOM   8254  C CB  . SER C 1 94  ? 105.936 127.492 115.920 1.00 31.92  ? 94  SER C CB  1 
ATOM   8255  O OG  . SER C 1 94  ? 105.461 128.708 116.468 1.00 31.92  ? 94  SER C OG  1 
ATOM   8256  N N   . ALA C 1 95  ? 108.434 129.534 114.351 1.00 31.59  ? 95  ALA C N   1 
ATOM   8257  C CA  . ALA C 1 95  ? 108.617 130.496 113.273 1.00 31.59  ? 95  ALA C CA  1 
ATOM   8258  C C   . ALA C 1 95  ? 109.114 129.809 112.004 1.00 31.59  ? 95  ALA C C   1 
ATOM   8259  O O   . ALA C 1 95  ? 109.863 128.830 112.053 1.00 31.59  ? 95  ALA C O   1 
ATOM   8260  C CB  . ALA C 1 95  ? 109.600 131.587 113.695 1.00 31.59  ? 95  ALA C CB  1 
ATOM   8261  N N   . PHE C 1 96  ? 108.691 130.339 110.857 1.00 30.20  ? 96  PHE C N   1 
ATOM   8262  C CA  . PHE C 1 96  ? 109.061 129.780 109.563 1.00 30.20  ? 96  PHE C CA  1 
ATOM   8263  C C   . PHE C 1 96  ? 109.161 130.900 108.535 1.00 30.20  ? 96  PHE C C   1 
ATOM   8264  O O   . PHE C 1 96  ? 108.652 132.004 108.739 1.00 30.20  ? 96  PHE C O   1 
ATOM   8265  C CB  . PHE C 1 96  ? 108.061 128.708 109.104 1.00 30.20  ? 96  PHE C CB  1 
ATOM   8266  C CG  . PHE C 1 96  ? 106.666 129.228 108.875 1.00 30.20  ? 96  PHE C CG  1 
ATOM   8267  C CD1 . PHE C 1 96  ? 105.767 129.322 109.923 1.00 30.20  ? 96  PHE C CD1 1 
ATOM   8268  C CD2 . PHE C 1 96  ? 106.252 129.609 107.611 1.00 30.20  ? 96  PHE C CD2 1 
ATOM   8269  C CE1 . PHE C 1 96  ? 104.487 129.796 109.715 1.00 30.20  ? 96  PHE C CE1 1 
ATOM   8270  C CE2 . PHE C 1 96  ? 104.973 130.082 107.398 1.00 30.20  ? 96  PHE C CE2 1 
ATOM   8271  C CZ  . PHE C 1 96  ? 104.089 130.174 108.452 1.00 30.20  ? 96  PHE C CZ  1 
ATOM   8272  N N   . SER C 1 97  ? 109.827 130.599 107.423 1.00 29.21  ? 97  SER C N   1 
ATOM   8273  C CA  . SER C 1 97  ? 110.008 131.530 106.317 1.00 29.21  ? 97  SER C CA  1 
ATOM   8274  C C   . SER C 1 97  ? 109.168 131.086 105.127 1.00 29.21  ? 97  SER C C   1 
ATOM   8275  O O   . SER C 1 97  ? 109.043 129.888 104.859 1.00 29.21  ? 97  SER C O   1 
ATOM   8276  C CB  . SER C 1 97  ? 111.480 131.621 105.910 1.00 29.21  ? 97  SER C CB  1 
ATOM   8277  O OG  . SER C 1 97  ? 112.230 132.356 106.858 1.00 29.21  ? 97  SER C OG  1 
ATOM   8278  N N   . ASN C 1 98  ? 108.584 132.053 104.421 1.00 28.85  ? 98  ASN C N   1 
ATOM   8279  C CA  . ASN C 1 98  ? 107.659 131.761 103.328 1.00 28.85  ? 98  ASN C CA  1 
ATOM   8280  C C   . ASN C 1 98  ? 107.879 132.704 102.147 1.00 28.85  ? 98  ASN C C   1 
ATOM   8281  O O   . ASN C 1 98  ? 106.924 133.226 101.565 1.00 28.85  ? 98  ASN C O   1 
ATOM   8282  C CB  . ASN C 1 98  ? 106.212 131.834 103.815 1.00 28.85  ? 98  ASN C CB  1 
ATOM   8283  C CG  . ASN C 1 98  ? 105.293 130.901 103.058 1.00 28.85  ? 98  ASN C CG  1 
ATOM   8284  O OD1 . ASN C 1 98  ? 105.664 129.777 102.730 1.00 28.85  ? 98  ASN C OD1 1 
ATOM   8285  N ND2 . ASN C 1 98  ? 104.081 131.362 102.783 1.00 28.85  ? 98  ASN C ND2 1 
ATOM   8286  N N   . CYS C 1 99  ? 109.131 132.937 101.773 1.00 27.67  ? 99  CYS C N   1 
ATOM   8287  C CA  . CYS C 1 99  ? 109.455 133.851 100.678 1.00 27.67  ? 99  CYS C CA  1 
ATOM   8288  C C   . CYS C 1 99  ? 110.595 133.232 99.872  1.00 27.67  ? 99  CYS C C   1 
ATOM   8289  O O   . CYS C 1 99  ? 110.867 132.031 99.966  1.00 27.67  ? 99  CYS C O   1 
ATOM   8290  C CB  . CYS C 1 99  ? 109.771 135.256 101.221 1.00 27.67  ? 99  CYS C CB  1 
ATOM   8291  S SG  . CYS C 1 99  ? 109.705 136.616 100.005 1.00 27.67  ? 99  CYS C SG  1 
ATOM   8292  N N   . TYR C 1 100 ? 111.251 134.043 99.045  1.00 24.00  ? 100 TYR C N   1 
ATOM   8293  C CA  . TYR C 1 100 ? 112.357 133.555 98.228  1.00 24.00  ? 100 TYR C CA  1 
ATOM   8294  C C   . TYR C 1 100 ? 113.498 133.065 99.119  1.00 24.00  ? 100 TYR C C   1 
ATOM   8295  O O   . TYR C 1 100 ? 113.849 133.742 100.094 1.00 24.00  ? 100 TYR C O   1 
ATOM   8296  C CB  . TYR C 1 100 ? 112.853 134.658 97.291  1.00 24.00  ? 100 TYR C CB  1 
ATOM   8297  C CG  . TYR C 1 100 ? 113.569 134.151 96.056  1.00 24.00  ? 100 TYR C CG  1 
ATOM   8298  C CD1 . TYR C 1 100 ? 112.871 133.868 94.890  1.00 24.00  ? 100 TYR C CD1 1 
ATOM   8299  C CD2 . TYR C 1 100 ? 114.942 133.951 96.060  1.00 24.00  ? 100 TYR C CD2 1 
ATOM   8300  C CE1 . TYR C 1 100 ? 113.520 133.403 93.764  1.00 24.00  ? 100 TYR C CE1 1 
ATOM   8301  C CE2 . TYR C 1 100 ? 115.600 133.483 94.942  1.00 24.00  ? 100 TYR C CE2 1 
ATOM   8302  C CZ  . TYR C 1 100 ? 114.886 133.212 93.797  1.00 24.00  ? 100 TYR C CZ  1 
ATOM   8303  O OH  . TYR C 1 100 ? 115.543 132.748 92.684  1.00 24.00  ? 100 TYR C OH  1 
ATOM   8304  N N   . PRO C 1 101 ? 114.085 131.902 98.834  1.00 23.17  ? 101 PRO C N   1 
ATOM   8305  C CA  . PRO C 1 101 ? 115.182 131.405 99.677  1.00 23.17  ? 101 PRO C CA  1 
ATOM   8306  C C   . PRO C 1 101 ? 116.376 132.350 99.667  1.00 23.17  ? 101 PRO C C   1 
ATOM   8307  O O   . PRO C 1 101 ? 116.747 132.903 98.631  1.00 23.17  ? 101 PRO C O   1 
ATOM   8308  C CB  . PRO C 1 101 ? 115.528 130.049 99.049  1.00 23.17  ? 101 PRO C CB  1 
ATOM   8309  C CG  . PRO C 1 101 ? 114.969 130.098 97.673  1.00 23.17  ? 101 PRO C CG  1 
ATOM   8310  C CD  . PRO C 1 101 ? 113.764 130.977 97.736  1.00 23.17  ? 101 PRO C CD  1 
ATOM   8311  N N   . TYR C 1 102 ? 116.984 132.521 100.839 1.00 23.32  ? 102 TYR C N   1 
ATOM   8312  C CA  . TYR C 1 102 ? 118.056 133.488 101.017 1.00 23.32  ? 102 TYR C CA  1 
ATOM   8313  C C   . TYR C 1 102 ? 119.000 133.003 102.108 1.00 23.32  ? 102 TYR C C   1 
ATOM   8314  O O   . TYR C 1 102 ? 118.698 132.070 102.853 1.00 23.32  ? 102 TYR C O   1 
ATOM   8315  C CB  . TYR C 1 102 ? 117.502 134.878 101.357 1.00 23.32  ? 102 TYR C CB  1 
ATOM   8316  C CG  . TYR C 1 102 ? 116.932 134.982 102.754 1.00 23.32  ? 102 TYR C CG  1 
ATOM   8317  C CD1 . TYR C 1 102 ? 115.600 134.686 103.001 1.00 23.32  ? 102 TYR C CD1 1 
ATOM   8318  C CD2 . TYR C 1 102 ? 117.726 135.366 103.826 1.00 23.32  ? 102 TYR C CD2 1 
ATOM   8319  C CE1 . TYR C 1 102 ? 115.074 134.771 104.270 1.00 23.32  ? 102 TYR C CE1 1 
ATOM   8320  C CE2 . TYR C 1 102 ? 117.210 135.451 105.101 1.00 23.32  ? 102 TYR C CE2 1 
ATOM   8321  C CZ  . TYR C 1 102 ? 115.882 135.153 105.317 1.00 23.32  ? 102 TYR C CZ  1 
ATOM   8322  O OH  . TYR C 1 102 ? 115.361 135.240 106.585 1.00 23.32  ? 102 TYR C OH  1 
ATOM   8323  N N   . ASP C 1 103 ? 120.157 133.656 102.192 1.00 24.34  ? 103 ASP C N   1 
ATOM   8324  C CA  . ASP C 1 103 ? 121.099 133.445 103.280 1.00 24.34  ? 103 ASP C CA  1 
ATOM   8325  C C   . ASP C 1 103 ? 121.745 134.775 103.641 1.00 24.34  ? 103 ASP C C   1 
ATOM   8326  O O   . ASP C 1 103 ? 121.752 135.721 102.850 1.00 24.34  ? 103 ASP C O   1 
ATOM   8327  C CB  . ASP C 1 103 ? 122.177 132.415 102.917 1.00 24.34  ? 103 ASP C CB  1 
ATOM   8328  C CG  . ASP C 1 103 ? 123.029 132.853 101.746 1.00 24.34  ? 103 ASP C CG  1 
ATOM   8329  O OD1 . ASP C 1 103 ? 122.628 132.600 100.591 1.00 24.34  ? 103 ASP C OD1 1 
ATOM   8330  O OD2 . ASP C 1 103 ? 124.100 133.450 101.979 1.00 24.34  ? 103 ASP C OD2 1 
ATOM   8331  N N   . VAL C 1 104 ? 122.285 134.839 104.853 1.00 23.23  ? 104 VAL C N   1 
ATOM   8332  C CA  . VAL C 1 104 ? 122.945 136.043 105.353 1.00 23.23  ? 104 VAL C CA  1 
ATOM   8333  C C   . VAL C 1 104 ? 124.347 135.687 105.831 1.00 23.23  ? 104 VAL C C   1 
ATOM   8334  O O   . VAL C 1 104 ? 124.490 134.982 106.839 1.00 23.23  ? 104 VAL C O   1 
ATOM   8335  C CB  . VAL C 1 104 ? 122.141 136.698 106.490 1.00 23.23  ? 104 VAL C CB  1 
ATOM   8336  C CG1 . VAL C 1 104 ? 122.761 138.029 106.882 1.00 23.23  ? 104 VAL C CG1 1 
ATOM   8337  C CG2 . VAL C 1 104 ? 120.686 136.876 106.099 1.00 23.23  ? 104 VAL C CG2 1 
ATOM   8338  N N   . PRO C 1 105 ? 125.401 136.131 105.150 1.00 24.54  ? 105 PRO C N   1 
ATOM   8339  C CA  . PRO C 1 105 ? 126.746 136.000 105.724 1.00 24.54  ? 105 PRO C CA  1 
ATOM   8340  C C   . PRO C 1 105 ? 126.836 136.774 107.032 1.00 24.54  ? 105 PRO C C   1 
ATOM   8341  O O   . PRO C 1 105 ? 126.483 137.953 107.100 1.00 24.54  ? 105 PRO C O   1 
ATOM   8342  C CB  . PRO C 1 105 ? 127.658 136.593 104.643 1.00 24.54  ? 105 PRO C CB  1 
ATOM   8343  C CG  . PRO C 1 105 ? 126.843 136.598 103.396 1.00 24.54  ? 105 PRO C CG  1 
ATOM   8344  C CD  . PRO C 1 105 ? 125.419 136.744 103.813 1.00 24.54  ? 105 PRO C CD  1 
ATOM   8345  N N   . ASP C 1 106 ? 127.316 136.098 108.073 1.00 26.57  ? 106 ASP C N   1 
ATOM   8346  C CA  . ASP C 1 106 ? 127.281 136.610 109.444 1.00 26.57  ? 106 ASP C CA  1 
ATOM   8347  C C   . ASP C 1 106 ? 125.858 137.010 109.841 1.00 26.57  ? 106 ASP C C   1 
ATOM   8348  O O   . ASP C 1 106 ? 125.556 138.168 110.128 1.00 26.57  ? 106 ASP C O   1 
ATOM   8349  C CB  . ASP C 1 106 ? 128.260 137.772 109.631 1.00 26.57  ? 106 ASP C CB  1 
ATOM   8350  C CG  . ASP C 1 106 ? 128.843 137.820 111.033 1.00 26.57  ? 106 ASP C CG  1 
ATOM   8351  O OD1 . ASP C 1 106 ? 128.363 137.065 111.907 1.00 26.57  ? 106 ASP C OD1 1 
ATOM   8352  O OD2 . ASP C 1 106 ? 129.779 138.613 111.263 1.00 26.57  ? 106 ASP C OD2 1 
ATOM   8353  N N   . TYR C 1 107 ? 124.984 136.002 109.854 1.00 24.37  ? 107 TYR C N   1 
ATOM   8354  C CA  . TYR C 1 107 ? 123.596 136.193 110.266 1.00 24.37  ? 107 TYR C CA  1 
ATOM   8355  C C   . TYR C 1 107 ? 123.505 136.694 111.705 1.00 24.37  ? 107 TYR C C   1 
ATOM   8356  O O   . TYR C 1 107 ? 122.703 137.586 112.015 1.00 24.37  ? 107 TYR C O   1 
ATOM   8357  C CB  . TYR C 1 107 ? 122.845 134.871 110.099 1.00 24.37  ? 107 TYR C CB  1 
ATOM   8358  C CG  . TYR C 1 107 ? 121.395 134.873 110.518 1.00 24.37  ? 107 TYR C CG  1 
ATOM   8359  C CD1 . TYR C 1 107 ? 121.024 134.561 111.820 1.00 24.37  ? 107 TYR C CD1 1 
ATOM   8360  C CD2 . TYR C 1 107 ? 120.393 135.150 109.602 1.00 24.37  ? 107 TYR C CD2 1 
ATOM   8361  C CE1 . TYR C 1 107 ? 119.700 134.551 112.200 1.00 24.37  ? 107 TYR C CE1 1 
ATOM   8362  C CE2 . TYR C 1 107 ? 119.067 135.140 109.972 1.00 24.37  ? 107 TYR C CE2 1 
ATOM   8363  C CZ  . TYR C 1 107 ? 118.725 134.841 111.271 1.00 24.37  ? 107 TYR C CZ  1 
ATOM   8364  O OH  . TYR C 1 107 ? 117.403 134.830 111.640 1.00 24.37  ? 107 TYR C OH  1 
ATOM   8365  N N   . ALA C 1 108 ? 124.326 136.130 112.594 1.00 24.93  ? 108 ALA C N   1 
ATOM   8366  C CA  . ALA C 1 108 ? 124.236 136.452 114.014 1.00 24.93  ? 108 ALA C CA  1 
ATOM   8367  C C   . ALA C 1 108 ? 124.537 137.922 114.281 1.00 24.93  ? 108 ALA C C   1 
ATOM   8368  O O   . ALA C 1 108 ? 123.882 138.550 115.119 1.00 24.93  ? 108 ALA C O   1 
ATOM   8369  C CB  . ALA C 1 108 ? 125.179 135.553 114.812 1.00 24.93  ? 108 ALA C CB  1 
ATOM   8370  N N   . SER C 1 109 ? 125.524 138.489 113.583 1.00 25.47  ? 109 SER C N   1 
ATOM   8371  C CA  . SER C 1 109 ? 125.873 139.891 113.804 1.00 25.47  ? 109 SER C CA  1 
ATOM   8372  C C   . SER C 1 109 ? 124.741 140.828 113.395 1.00 25.47  ? 109 SER C C   1 
ATOM   8373  O O   . SER C 1 109 ? 124.422 141.774 114.124 1.00 25.47  ? 109 SER C O   1 
ATOM   8374  C CB  . SER C 1 109 ? 127.155 140.238 113.049 1.00 25.47  ? 109 SER C CB  1 
ATOM   8375  O OG  . SER C 1 109 ? 128.300 139.865 113.793 1.00 25.47  ? 109 SER C OG  1 
ATOM   8376  N N   . LEU C 1 110 ? 124.120 140.586 112.236 1.00 24.05  ? 110 LEU C N   1 
ATOM   8377  C CA  . LEU C 1 110 ? 123.002 141.426 111.815 1.00 24.05  ? 110 LEU C CA  1 
ATOM   8378  C C   . LEU C 1 110 ? 121.812 141.269 112.753 1.00 24.05  ? 110 LEU C C   1 
ATOM   8379  O O   . LEU C 1 110 ? 121.138 142.254 113.082 1.00 24.05  ? 110 LEU C O   1 
ATOM   8380  C CB  . LEU C 1 110 ? 122.603 141.100 110.375 1.00 24.05  ? 110 LEU C CB  1 
ATOM   8381  C CG  . LEU C 1 110 ? 121.519 141.979 109.740 1.00 24.05  ? 110 LEU C CG  1 
ATOM   8382  C CD1 . LEU C 1 110 ? 121.944 143.439 109.694 1.00 24.05  ? 110 LEU C CD1 1 
ATOM   8383  C CD2 . LEU C 1 110 ? 121.153 141.486 108.351 1.00 24.05  ? 110 LEU C CD2 1 
ATOM   8384  N N   . ARG C 1 111 ? 121.539 140.037 113.194 1.00 24.66  ? 111 ARG C N   1 
ATOM   8385  C CA  . ARG C 1 111 ? 120.456 139.816 114.147 1.00 24.66  ? 111 ARG C CA  1 
ATOM   8386  C C   . ARG C 1 111 ? 120.704 140.581 115.443 1.00 24.66  ? 111 ARG C C   1 
ATOM   8387  O O   . ARG C 1 111 ? 119.807 141.257 115.959 1.00 24.66  ? 111 ARG C O   1 
ATOM   8388  C CB  . ARG C 1 111 ? 120.298 138.316 114.416 1.00 24.66  ? 111 ARG C CB  1 
ATOM   8389  C CG  . ARG C 1 111 ? 119.222 137.939 115.429 1.00 24.66  ? 111 ARG C CG  1 
ATOM   8390  C CD  . ARG C 1 111 ? 119.153 136.426 115.597 1.00 24.66  ? 111 ARG C CD  1 
ATOM   8391  N NE  . ARG C 1 111 ? 118.199 136.000 116.614 1.00 24.66  ? 111 ARG C NE  1 
ATOM   8392  C CZ  . ARG C 1 111 ? 118.500 135.800 117.890 1.00 24.66  ? 111 ARG C CZ  1 
ATOM   8393  N NH1 . ARG C 1 111 ? 119.723 136.000 118.350 1.00 24.66  ? 111 ARG C NH1 1 
ATOM   8394  N NH2 . ARG C 1 111 ? 117.552 135.382 118.722 1.00 24.66  ? 111 ARG C NH2 1 
ATOM   8395  N N   . SER C 1 112 ? 121.931 140.508 115.967 1.00 25.90  ? 112 SER C N   1 
ATOM   8396  C CA  . SER C 1 112 ? 122.263 141.213 117.201 1.00 25.90  ? 112 SER C CA  1 
ATOM   8397  C C   . SER C 1 112 ? 122.157 142.723 117.023 1.00 25.90  ? 112 SER C C   1 
ATOM   8398  O O   . SER C 1 112 ? 121.651 143.425 117.906 1.00 25.90  ? 112 SER C O   1 
ATOM   8399  C CB  . SER C 1 112 ? 123.666 140.820 117.662 1.00 25.90  ? 112 SER C CB  1 
ATOM   8400  O OG  . SER C 1 112 ? 124.174 141.740 118.608 1.00 25.90  ? 112 SER C OG  1 
ATOM   8401  N N   . LEU C 1 113 ? 122.621 143.235 115.883 1.00 26.14  ? 113 LEU C N   1 
ATOM   8402  C CA  . LEU C 1 113 ? 122.551 144.666 115.600 1.00 26.14  ? 113 LEU C CA  1 
ATOM   8403  C C   . LEU C 1 113 ? 121.108 145.160 115.584 1.00 26.14  ? 113 LEU C C   1 
ATOM   8404  O O   . LEU C 1 113 ? 120.765 146.149 116.249 1.00 26.14  ? 113 LEU C O   1 
ATOM   8405  C CB  . LEU C 1 113 ? 123.250 144.933 114.265 1.00 26.14  ? 113 LEU C CB  1 
ATOM   8406  C CG  . LEU C 1 113 ? 123.572 146.311 113.695 1.00 26.14  ? 113 LEU C CG  1 
ATOM   8407  C CD1 . LEU C 1 113 ? 124.610 146.134 112.608 1.00 26.14  ? 113 LEU C CD1 1 
ATOM   8408  C CD2 . LEU C 1 113 ? 122.340 146.963 113.109 1.00 26.14  ? 113 LEU C CD2 1 
ATOM   8409  N N   . ILE C 1 114 ? 120.242 144.474 114.832 1.00 25.95  ? 114 ILE C N   1 
ATOM   8410  C CA  . ILE C 1 114 ? 118.845 144.892 114.743 1.00 25.95  ? 114 ILE C CA  1 
ATOM   8411  C C   . ILE C 1 114 ? 118.155 144.769 116.096 1.00 25.95  ? 114 ILE C C   1 
ATOM   8412  O O   . ILE C 1 114 ? 117.374 145.643 116.489 1.00 25.95  ? 114 ILE C O   1 
ATOM   8413  C CB  . ILE C 1 114 ? 118.108 144.088 113.658 1.00 25.95  ? 114 ILE C CB  1 
ATOM   8414  C CG1 . ILE C 1 114 ? 118.804 144.253 112.309 1.00 25.95  ? 114 ILE C CG1 1 
ATOM   8415  C CG2 . ILE C 1 114 ? 116.660 144.534 113.560 1.00 25.95  ? 114 ILE C CG2 1 
ATOM   8416  C CD1 . ILE C 1 114 ? 118.993 145.686 111.901 1.00 25.95  ? 114 ILE C CD1 1 
ATOM   8417  N N   . ALA C 1 115 ? 118.423 143.682 116.827 1.00 25.64  ? 115 ALA C N   1 
ATOM   8418  C CA  . ALA C 1 115 ? 117.801 143.507 118.136 1.00 25.64  ? 115 ALA C CA  1 
ATOM   8419  C C   . ALA C 1 115 ? 118.225 144.605 119.100 1.00 25.64  ? 115 ALA C C   1 
ATOM   8420  O O   . ALA C 1 115 ? 117.400 145.130 119.856 1.00 25.64  ? 115 ALA C O   1 
ATOM   8421  C CB  . ALA C 1 115 ? 118.150 142.133 118.703 1.00 25.64  ? 115 ALA C CB  1 
ATOM   8422  N N   . SER C 1 116 ? 119.509 144.972 119.082 1.00 27.95  ? 116 SER C N   1 
ATOM   8423  C CA  . SER C 1 116 ? 119.998 146.016 119.974 1.00 27.95  ? 116 SER C CA  1 
ATOM   8424  C C   . SER C 1 116 ? 119.407 147.373 119.621 1.00 27.95  ? 116 SER C C   1 
ATOM   8425  O O   . SER C 1 116 ? 119.125 148.181 120.513 1.00 27.95  ? 116 SER C O   1 
ATOM   8426  C CB  . SER C 1 116 ? 121.523 146.069 119.930 1.00 27.95  ? 116 SER C CB  1 
ATOM   8427  O OG  . SER C 1 116 ? 122.058 146.303 121.216 1.00 27.95  ? 116 SER C OG  1 
ATOM   8428  N N   . SER C 1 117 ? 119.218 147.648 118.327 1.00 28.56  ? 117 SER C N   1 
ATOM   8429  C CA  . SER C 1 117 ? 118.668 148.942 117.932 1.00 28.56  ? 117 SER C CA  1 
ATOM   8430  C C   . SER C 1 117 ? 117.271 149.156 118.507 1.00 28.56  ? 117 SER C C   1 
ATOM   8431  O O   . SER C 1 117 ? 116.957 150.243 119.000 1.00 28.56  ? 117 SER C O   1 
ATOM   8432  C CB  . SER C 1 117 ? 118.650 149.063 116.410 1.00 28.56  ? 117 SER C CB  1 
ATOM   8433  O OG  . SER C 1 117 ? 118.150 150.325 116.012 1.00 28.56  ? 117 SER C OG  1 
ATOM   8434  N N   . GLY C 1 118 ? 116.421 148.135 118.451 1.00 27.41  ? 118 GLY C N   1 
ATOM   8435  C CA  . GLY C 1 118 ? 115.126 148.178 119.098 1.00 27.41  ? 118 GLY C CA  1 
ATOM   8436  C C   . GLY C 1 118 ? 113.980 148.750 118.294 1.00 27.41  ? 118 GLY C C   1 
ATOM   8437  O O   . GLY C 1 118 ? 112.909 148.983 118.866 1.00 27.41  ? 118 GLY C O   1 
ATOM   8438  N N   . THR C 1 119 ? 114.154 148.975 116.993 1.00 29.63  ? 119 THR C N   1 
ATOM   8439  C CA  . THR C 1 119 ? 113.091 149.545 116.178 1.00 29.63  ? 119 THR C CA  1 
ATOM   8440  C C   . THR C 1 119 ? 113.226 149.050 114.744 1.00 29.63  ? 119 THR C C   1 
ATOM   8441  O O   . THR C 1 119 ? 114.295 148.614 114.314 1.00 29.63  ? 119 THR C O   1 
ATOM   8442  C CB  . THR C 1 119 ? 113.113 151.081 116.219 1.00 29.63  ? 119 THR C CB  1 
ATOM   8443  O OG1 . THR C 1 119 ? 111.987 151.600 115.503 1.00 29.63  ? 119 THR C OG1 1 
ATOM   8444  C CG2 . THR C 1 119 ? 114.393 151.619 115.600 1.00 29.63  ? 119 THR C CG2 1 
ATOM   8445  N N   . LEU C 1 120 ? 112.116 149.124 114.006 1.00 28.50  ? 120 LEU C N   1 
ATOM   8446  C CA  . LEU C 1 120 ? 112.074 148.772 112.591 1.00 28.50  ? 120 LEU C CA  1 
ATOM   8447  C C   . LEU C 1 120 ? 111.557 149.929 111.739 1.00 28.50  ? 120 LEU C C   1 
ATOM   8448  O O   . LEU C 1 120 ? 110.949 149.708 110.692 1.00 28.50  ? 120 LEU C O   1 
ATOM   8449  C CB  . LEU C 1 120 ? 111.217 147.528 112.361 1.00 28.50  ? 120 LEU C CB  1 
ATOM   8450  C CG  . LEU C 1 120 ? 111.789 146.168 112.763 1.00 28.50  ? 120 LEU C CG  1 
ATOM   8451  C CD1 . LEU C 1 120 ? 110.860 145.048 112.329 1.00 28.50  ? 120 LEU C CD1 1 
ATOM   8452  C CD2 . LEU C 1 120 ? 113.175 145.972 112.182 1.00 28.50  ? 120 LEU C CD2 1 
ATOM   8453  N N   . ASP C 1 121 ? 111.791 151.165 112.173 1.00 29.51  ? 121 ASP C N   1 
ATOM   8454  C CA  . ASP C 1 121 ? 111.294 152.325 111.442 1.00 29.51  ? 121 ASP C CA  1 
ATOM   8455  C C   . ASP C 1 121 ? 112.034 152.486 110.117 1.00 29.51  ? 121 ASP C C   1 
ATOM   8456  O O   . ASP C 1 121 ? 113.265 152.554 110.084 1.00 29.51  ? 121 ASP C O   1 
ATOM   8457  C CB  . ASP C 1 121 ? 111.441 153.585 112.290 1.00 29.51  ? 121 ASP C CB  1 
ATOM   8458  C CG  . ASP C 1 121 ? 110.711 154.772 111.698 1.00 29.51  ? 121 ASP C CG  1 
ATOM   8459  O OD1 . ASP C 1 121 ? 109.471 154.703 111.562 1.00 29.51  ? 121 ASP C OD1 1 
ATOM   8460  O OD2 . ASP C 1 121 ? 111.375 155.775 111.368 1.00 29.51  ? 121 ASP C OD2 1 
ATOM   8461  N N   . PHE C 1 122 ? 111.274 152.563 109.028 1.00 23.92  ? 122 PHE C N   1 
ATOM   8462  C CA  . PHE C 1 122 ? 111.802 152.569 107.671 1.00 23.92  ? 122 PHE C CA  1 
ATOM   8463  C C   . PHE C 1 122 ? 111.366 153.840 106.955 1.00 23.92  ? 122 PHE C C   1 
ATOM   8464  O O   . PHE C 1 122 ? 110.207 154.252 107.056 1.00 23.92  ? 122 PHE C O   1 
ATOM   8465  C CB  . PHE C 1 122 ? 111.317 151.324 106.907 1.00 23.92  ? 122 PHE C CB  1 
ATOM   8466  C CG  . PHE C 1 122 ? 111.976 151.118 105.569 1.00 23.92  ? 122 PHE C CG  1 
ATOM   8467  C CD1 . PHE C 1 122 ? 113.204 150.486 105.476 1.00 23.92  ? 122 PHE C CD1 1 
ATOM   8468  C CD2 . PHE C 1 122 ? 111.348 151.519 104.403 1.00 23.92  ? 122 PHE C CD2 1 
ATOM   8469  C CE1 . PHE C 1 122 ? 113.804 150.285 104.250 1.00 23.92  ? 122 PHE C CE1 1 
ATOM   8470  C CE2 . PHE C 1 122 ? 111.943 151.317 103.174 1.00 23.92  ? 122 PHE C CE2 1 
ATOM   8471  C CZ  . PHE C 1 122 ? 113.170 150.697 103.098 1.00 23.92  ? 122 PHE C CZ  1 
ATOM   8472  N N   . ILE C 1 123 ? 112.299 154.462 106.237 1.00 24.65  ? 123 ILE C N   1 
ATOM   8473  C CA  . ILE C 1 123 ? 112.039 155.665 105.454 1.00 24.65  ? 123 ILE C CA  1 
ATOM   8474  C C   . ILE C 1 123 ? 112.305 155.339 103.991 1.00 24.65  ? 123 ILE C C   1 
ATOM   8475  O O   . ILE C 1 123 ? 113.400 154.880 103.643 1.00 24.65  ? 123 ILE C O   1 
ATOM   8476  C CB  . ILE C 1 123 ? 112.906 156.850 105.911 1.00 24.65  ? 123 ILE C CB  1 
ATOM   8477  C CG1 . ILE C 1 123 ? 112.724 157.114 107.409 1.00 24.65  ? 123 ILE C CG1 1 
ATOM   8478  C CG2 . ILE C 1 123 ? 112.584 158.093 105.094 1.00 24.65  ? 123 ILE C CG2 1 
ATOM   8479  C CD1 . ILE C 1 123 ? 111.443 157.821 107.758 1.00 24.65  ? 123 ILE C CD1 1 
ATOM   8480  N N   . THR C 1 124 ? 111.308 155.575 103.143 1.00 26.99  ? 124 THR C N   1 
ATOM   8481  C CA  . THR C 1 124 ? 111.440 155.348 101.710 1.00 26.99  ? 124 THR C CA  1 
ATOM   8482  C C   . THR C 1 124 ? 112.186 156.502 101.049 1.00 26.99  ? 124 THR C C   1 
ATOM   8483  O O   . THR C 1 124 ? 111.981 157.668 101.391 1.00 26.99  ? 124 THR C O   1 
ATOM   8484  C CB  . THR C 1 124 ? 110.061 155.181 101.069 1.00 26.99  ? 124 THR C CB  1 
ATOM   8485  O OG1 . THR C 1 124 ? 109.298 154.228 101.817 1.00 26.99  ? 124 THR C OG1 1 
ATOM   8486  C CG2 . THR C 1 124 ? 110.180 154.700 99.632  1.00 26.99  ? 124 THR C CG2 1 
ATOM   8487  N N   . GLU C 1 125 ? 113.051 156.170 100.095 1.00 28.51  ? 125 GLU C N   1 
ATOM   8488  C CA  . GLU C 1 125 ? 113.822 157.156 99.354  1.00 28.51  ? 125 GLU C CA  1 
ATOM   8489  C C   . GLU C 1 125 ? 113.549 157.012 97.863  1.00 28.51  ? 125 GLU C C   1 
ATOM   8490  O O   . GLU C 1 125 ? 113.050 155.985 97.398  1.00 28.51  ? 125 GLU C O   1 
ATOM   8491  C CB  . GLU C 1 125 ? 115.320 157.017 99.638  1.00 28.51  ? 125 GLU C CB  1 
ATOM   8492  C CG  . GLU C 1 125 ? 115.740 157.622 100.962 1.00 28.51  ? 125 GLU C CG  1 
ATOM   8493  C CD  . GLU C 1 125 ? 117.216 157.453 101.246 1.00 28.51  ? 125 GLU C CD  1 
ATOM   8494  O OE1 . GLU C 1 125 ? 117.775 156.397 100.890 1.00 28.51  ? 125 GLU C OE1 1 
ATOM   8495  O OE2 . GLU C 1 125 ? 117.817 158.378 101.827 1.00 28.51  ? 125 GLU C OE2 1 
ATOM   8496  N N   . SER C 1 126 ? 113.876 158.064 97.113  1.00 30.43  ? 126 SER C N   1 
ATOM   8497  C CA  . SER C 1 126 ? 113.567 158.131 95.685  1.00 30.43  ? 126 SER C CA  1 
ATOM   8498  C C   . SER C 1 126 ? 114.810 157.757 94.882  1.00 30.43  ? 126 SER C C   1 
ATOM   8499  O O   . SER C 1 126 ? 115.564 158.607 94.411  1.00 30.43  ? 126 SER C O   1 
ATOM   8500  C CB  . SER C 1 126 ? 113.050 159.518 95.314  1.00 30.43  ? 126 SER C CB  1 
ATOM   8501  N N   . PHE C 1 127 ? 115.016 156.453 94.725  1.00 28.56  ? 127 PHE C N   1 
ATOM   8502  C CA  . PHE C 1 127 ? 116.065 155.947 93.852  1.00 28.56  ? 127 PHE C CA  1 
ATOM   8503  C C   . PHE C 1 127 ? 115.577 155.925 92.410  1.00 28.56  ? 127 PHE C C   1 
ATOM   8504  O O   . PHE C 1 127 ? 114.405 155.650 92.143  1.00 28.56  ? 127 PHE C O   1 
ATOM   8505  C CB  . PHE C 1 127 ? 116.484 154.539 94.273  1.00 28.56  ? 127 PHE C CB  1 
ATOM   8506  C CG  . PHE C 1 127 ? 117.293 154.490 95.536  1.00 28.56  ? 127 PHE C CG  1 
ATOM   8507  C CD1 . PHE C 1 127 ? 118.651 154.751 95.515  1.00 28.56  ? 127 PHE C CD1 1 
ATOM   8508  C CD2 . PHE C 1 127 ? 116.698 154.162 96.741  1.00 28.56  ? 127 PHE C CD2 1 
ATOM   8509  C CE1 . PHE C 1 127 ? 119.398 154.700 96.675  1.00 28.56  ? 127 PHE C CE1 1 
ATOM   8510  C CE2 . PHE C 1 127 ? 117.439 154.108 97.903  1.00 28.56  ? 127 PHE C CE2 1 
ATOM   8511  C CZ  . PHE C 1 127 ? 118.790 154.379 97.871  1.00 28.56  ? 127 PHE C CZ  1 
ATOM   8512  N N   . THR C 1 128 ? 116.480 156.214 91.479  1.00 30.34  ? 128 THR C N   1 
ATOM   8513  C CA  . THR C 1 128 ? 116.180 156.163 90.054  1.00 30.34  ? 128 THR C CA  1 
ATOM   8514  C C   . THR C 1 128 ? 117.022 155.071 89.407  1.00 30.34  ? 128 THR C C   1 
ATOM   8515  O O   . THR C 1 128 ? 118.254 155.121 89.459  1.00 30.34  ? 128 THR C O   1 
ATOM   8516  C CB  . THR C 1 128 ? 116.447 157.511 89.384  1.00 30.34  ? 128 THR C CB  1 
ATOM   8517  O OG1 . THR C 1 128 ? 115.605 158.511 89.967  1.00 30.34  ? 128 THR C OG1 1 
ATOM   8518  C CG2 . THR C 1 128 ? 116.155 157.424 87.897  1.00 30.34  ? 128 THR C CG2 1 
ATOM   8519  N N   . TRP C 1 129 ? 116.357 154.095 88.798  1.00 27.65  ? 129 TRP C N   1 
ATOM   8520  C CA  . TRP C 1 129 ? 117.013 152.979 88.122  1.00 27.65  ? 129 TRP C CA  1 
ATOM   8521  C C   . TRP C 1 129 ? 116.660 153.071 86.640  1.00 27.65  ? 129 TRP C C   1 
ATOM   8522  O O   . TRP C 1 129 ? 115.614 152.579 86.209  1.00 27.65  ? 129 TRP C O   1 
ATOM   8523  C CB  . TRP C 1 129 ? 116.582 151.647 88.730  1.00 27.65  ? 129 TRP C CB  1 
ATOM   8524  C CG  . TRP C 1 129 ? 116.637 151.616 90.232  1.00 27.65  ? 129 TRP C CG  1 
ATOM   8525  C CD1 . TRP C 1 129 ? 115.577 151.629 91.090  1.00 27.65  ? 129 TRP C CD1 1 
ATOM   8526  C CD2 . TRP C 1 129 ? 117.812 151.563 91.051  1.00 27.65  ? 129 TRP C CD2 1 
ATOM   8527  N NE1 . TRP C 1 129 ? 116.017 151.588 92.388  1.00 27.65  ? 129 TRP C NE1 1 
ATOM   8528  C CE2 . TRP C 1 129 ? 117.385 151.546 92.392  1.00 27.65  ? 129 TRP C CE2 1 
ATOM   8529  C CE3 . TRP C 1 129 ? 119.182 151.527 90.780  1.00 27.65  ? 129 TRP C CE3 1 
ATOM   8530  C CZ2 . TRP C 1 129 ? 118.278 151.499 93.459  1.00 27.65  ? 129 TRP C CZ2 1 
ATOM   8531  C CZ3 . TRP C 1 129 ? 120.067 151.477 91.840  1.00 27.65  ? 129 TRP C CZ3 1 
ATOM   8532  C CH2 . TRP C 1 129 ? 119.612 151.463 93.163  1.00 27.65  ? 129 TRP C CH2 1 
ATOM   8533  N N   . ALA C 1 130 ? 117.539 153.697 85.862  1.00 30.94  ? 130 ALA C N   1 
ATOM   8534  C CA  . ALA C 1 130 ? 117.247 154.046 84.477  1.00 30.94  ? 130 ALA C CA  1 
ATOM   8535  C C   . ALA C 1 130 ? 117.583 152.883 83.550  1.00 30.94  ? 130 ALA C C   1 
ATOM   8536  O O   . ALA C 1 130 ? 118.718 152.396 83.542  1.00 30.94  ? 130 ALA C O   1 
ATOM   8537  C CB  . ALA C 1 130 ? 118.027 155.296 84.069  1.00 30.94  ? 130 ALA C CB  1 
ATOM   8538  N N   . GLY C 1 131 ? 116.599 152.449 82.767  1.00 31.40  ? 131 GLY C N   1 
ATOM   8539  C CA  . GLY C 1 131 ? 116.822 151.443 81.749  1.00 31.40  ? 131 GLY C CA  1 
ATOM   8540  C C   . GLY C 1 131 ? 116.654 150.005 82.181  1.00 31.40  ? 131 GLY C C   1 
ATOM   8541  O O   . GLY C 1 131 ? 117.117 149.107 81.469  1.00 31.40  ? 131 GLY C O   1 
ATOM   8542  N N   . VAL C 1 132 ? 116.016 149.749 83.322  1.00 30.36  ? 132 VAL C N   1 
ATOM   8543  C CA  . VAL C 1 132 ? 115.782 148.392 83.797  1.00 30.36  ? 132 VAL C CA  1 
ATOM   8544  C C   . VAL C 1 132 ? 114.336 148.263 84.251  1.00 30.36  ? 132 VAL C C   1 
ATOM   8545  O O   . VAL C 1 132 ? 113.641 149.252 84.490  1.00 30.36  ? 132 VAL C O   1 
ATOM   8546  C CB  . VAL C 1 132 ? 116.736 147.992 84.945  1.00 30.36  ? 132 VAL C CB  1 
ATOM   8547  C CG1 . VAL C 1 132 ? 118.171 147.902 84.451  1.00 30.36  ? 132 VAL C CG1 1 
ATOM   8548  C CG2 . VAL C 1 132 ? 116.617 148.971 86.099  1.00 30.36  ? 132 VAL C CG2 1 
ATOM   8549  N N   . SER C 1 133 ? 113.887 147.016 84.360  1.00 30.96  ? 133 SER C N   1 
ATOM   8550  C CA  . SER C 1 133 ? 112.589 146.713 84.944  1.00 30.96  ? 133 SER C CA  1 
ATOM   8551  C C   . SER C 1 133 ? 112.693 146.648 86.464  1.00 30.96  ? 133 SER C C   1 
ATOM   8552  O O   . SER C 1 133 ? 113.717 146.240 87.018  1.00 30.96  ? 133 SER C O   1 
ATOM   8553  C CB  . SER C 1 133 ? 112.054 145.387 84.405  1.00 30.96  ? 133 SER C CB  1 
ATOM   8554  O OG  . SER C 1 133 ? 111.579 145.523 83.079  1.00 30.96  ? 133 SER C OG  1 
ATOM   8555  N N   . GLN C 1 134 ? 111.619 147.050 87.138  1.00 29.04  ? 134 GLN C N   1 
ATOM   8556  C CA  . GLN C 1 134 ? 111.559 147.053 88.593  1.00 29.04  ? 134 GLN C CA  1 
ATOM   8557  C C   . GLN C 1 134 ? 110.447 146.133 89.080  1.00 29.04  ? 134 GLN C C   1 
ATOM   8558  O O   . GLN C 1 134 ? 109.580 145.704 88.315  1.00 29.04  ? 134 GLN C O   1 
ATOM   8559  C CB  . GLN C 1 134 ? 111.344 148.471 89.141  1.00 29.04  ? 134 GLN C CB  1 
ATOM   8560  C CG  . GLN C 1 134 ? 112.201 149.540 88.492  1.00 29.04  ? 134 GLN C CG  1 
ATOM   8561  C CD  . GLN C 1 134 ? 112.201 150.839 89.276  1.00 29.04  ? 134 GLN C CD  1 
ATOM   8562  O OE1 . GLN C 1 134 ? 111.828 150.871 90.447  1.00 29.04  ? 134 GLN C OE1 1 
ATOM   8563  N NE2 . GLN C 1 134 ? 112.615 151.920 88.629  1.00 29.04  ? 134 GLN C NE2 1 
ATOM   8564  N N   . ASN C 1 135 ? 110.498 145.823 90.378  1.00 28.84  ? 135 ASN C N   1 
ATOM   8565  C CA  . ASN C 1 135 ? 109.463 145.046 91.067  1.00 28.84  ? 135 ASN C CA  1 
ATOM   8566  C C   . ASN C 1 135 ? 109.342 143.627 90.508  1.00 28.84  ? 135 ASN C C   1 
ATOM   8567  O O   . ASN C 1 135 ? 108.257 143.165 90.153  1.00 28.84  ? 135 ASN C O   1 
ATOM   8568  C CB  . ASN C 1 135 ? 108.110 145.764 91.023  1.00 28.84  ? 135 ASN C CB  1 
ATOM   8569  C CG  . ASN C 1 135 ? 108.206 147.217 91.436  1.00 28.84  ? 135 ASN C CG  1 
ATOM   8570  O OD1 . ASN C 1 135 ? 108.706 147.538 92.512  1.00 28.84  ? 135 ASN C OD1 1 
ATOM   8571  N ND2 . ASN C 1 135 ? 107.727 148.106 90.579  1.00 28.84  ? 135 ASN C ND2 1 
ATOM   8572  N N   . GLY C 1 136 ? 110.472 142.928 90.434  1.00 29.05  ? 136 GLY C N   1 
ATOM   8573  C CA  . GLY C 1 136 ? 110.438 141.518 90.100  1.00 29.05  ? 136 GLY C CA  1 
ATOM   8574  C C   . GLY C 1 136 ? 109.834 140.690 91.219  1.00 29.05  ? 136 GLY C C   1 
ATOM   8575  O O   . GLY C 1 136 ? 109.903 141.044 92.395  1.00 29.05  ? 136 GLY C O   1 
ATOM   8576  N N   . GLY C 1 137 ? 109.232 139.559 90.844  1.00 30.98  ? 137 GLY C N   1 
ATOM   8577  C CA  . GLY C 1 137 ? 108.531 138.717 91.792  1.00 30.98  ? 137 GLY C CA  1 
ATOM   8578  C C   . GLY C 1 137 ? 108.800 137.245 91.552  1.00 30.98  ? 137 GLY C C   1 
ATOM   8579  O O   . GLY C 1 137 ? 109.540 136.867 90.643  1.00 30.98  ? 137 GLY C O   1 
ATOM   8580  N N   . SER C 1 138 ? 108.178 136.418 92.389  1.00 31.42  ? 138 SER C N   1 
ATOM   8581  C CA  . SER C 1 138 ? 108.383 134.979 92.339  1.00 31.42  ? 138 SER C CA  1 
ATOM   8582  C C   . SER C 1 138 ? 107.146 134.272 92.873  1.00 31.42  ? 138 SER C C   1 
ATOM   8583  O O   . SER C 1 138 ? 106.375 134.831 93.656  1.00 31.42  ? 138 SER C O   1 
ATOM   8584  C CB  . SER C 1 138 ? 109.621 134.563 93.142  1.00 31.42  ? 138 SER C CB  1 
ATOM   8585  O OG  . SER C 1 138 ? 109.833 133.166 93.073  1.00 31.42  ? 138 SER C OG  1 
ATOM   8586  N N   . SER C 1 139 ? 106.968 133.024 92.442  1.00 32.06  ? 139 SER C N   1 
ATOM   8587  C CA  . SER C 1 139 ? 105.898 132.191 92.974  1.00 32.06  ? 139 SER C CA  1 
ATOM   8588  C C   . SER C 1 139 ? 106.241 131.594 94.331  1.00 32.06  ? 139 SER C C   1 
ATOM   8589  O O   . SER C 1 139 ? 105.355 131.039 94.987  1.00 32.06  ? 139 SER C O   1 
ATOM   8590  C CB  . SER C 1 139 ? 105.555 131.073 91.987  1.00 32.06  ? 139 SER C CB  1 
ATOM   8591  O OG  . SER C 1 139 ? 106.617 130.142 91.874  1.00 32.06  ? 139 SER C OG  1 
ATOM   8592  N N   . ALA C 1 140 ? 107.495 131.697 94.769  1.00 30.23  ? 140 ALA C N   1 
ATOM   8593  C CA  . ALA C 1 140 ? 107.876 131.255 96.101  1.00 30.23  ? 140 ALA C CA  1 
ATOM   8594  C C   . ALA C 1 140 ? 107.516 132.263 97.182  1.00 30.23  ? 140 ALA C C   1 
ATOM   8595  O O   . ALA C 1 140 ? 107.640 131.944 98.369  1.00 30.23  ? 140 ALA C O   1 
ATOM   8596  C CB  . ALA C 1 140 ? 109.376 130.963 96.151  1.00 30.23  ? 140 ALA C CB  1 
ATOM   8597  N N   . CYS C 1 141 ? 107.090 133.469 96.804  1.00 32.34  ? 141 CYS C N   1 
ATOM   8598  C CA  . CYS C 1 141 ? 106.723 134.524 97.752  1.00 32.34  ? 141 CYS C CA  1 
ATOM   8599  C C   . CYS C 1 141 ? 105.419 135.144 97.253  1.00 32.34  ? 141 CYS C C   1 
ATOM   8600  O O   . CYS C 1 141 ? 105.436 136.154 96.550  1.00 32.34  ? 141 CYS C O   1 
ATOM   8601  C CB  . CYS C 1 141 ? 107.844 135.553 97.861  1.00 32.34  ? 141 CYS C CB  1 
ATOM   8602  S SG  . CYS C 1 141 ? 107.796 136.627 99.307  1.00 32.34  ? 141 CYS C SG  1 
ATOM   8603  N N   . LYS C 1 142 ? 104.292 134.556 97.642  1.00 35.81  ? 142 LYS C N   1 
ATOM   8604  C CA  . LYS C 1 142 ? 102.995 134.965 97.117  1.00 35.81  ? 142 LYS C CA  1 
ATOM   8605  C C   . LYS C 1 142 ? 102.364 136.031 98.003  1.00 35.81  ? 142 LYS C C   1 
ATOM   8606  O O   . LYS C 1 142 ? 102.325 135.889 99.228  1.00 35.81  ? 142 LYS C O   1 
ATOM   8607  C CB  . LYS C 1 142 ? 102.054 133.765 96.997  1.00 35.81  ? 142 LYS C CB  1 
ATOM   8608  C CG  . LYS C 1 142 ? 102.676 132.555 96.336  1.00 35.81  ? 142 LYS C CG  1 
ATOM   8609  C CD  . LYS C 1 142 ? 101.791 132.017 95.232  1.00 35.81  ? 142 LYS C CD  1 
ATOM   8610  C CE  . LYS C 1 142 ? 101.932 132.845 93.971  1.00 35.81  ? 142 LYS C CE  1 
ATOM   8611  N NZ  . LYS C 1 142 ? 101.081 132.329 92.865  1.00 35.81  ? 142 LYS C NZ  1 
ATOM   8612  N N   . ARG C 1 143 ? 101.876 137.095 97.377  1.00 35.81  ? 143 ARG C N   1 
ATOM   8613  C CA  . ARG C 1 143 ? 101.103 138.140 98.043  1.00 35.81  ? 143 ARG C CA  1 
ATOM   8614  C C   . ARG C 1 143 ? 99.668  138.001 97.544  1.00 35.81  ? 143 ARG C C   1 
ATOM   8615  O O   . ARG C 1 143 ? 99.268  138.639 96.570  1.00 35.81  ? 143 ARG C O   1 
ATOM   8616  C CB  . ARG C 1 143 ? 101.669 139.523 97.754  1.00 35.81  ? 143 ARG C CB  1 
ATOM   8617  C CG  . ARG C 1 143 ? 103.058 139.752 98.315  1.00 35.81  ? 143 ARG C CG  1 
ATOM   8618  C CD  . ARG C 1 143 ? 103.423 141.225 98.312  1.00 35.81  ? 143 ARG C CD  1 
ATOM   8619  N NE  . ARG C 1 143 ? 104.568 141.490 99.173  1.00 35.81  ? 143 ARG C NE  1 
ATOM   8620  C CZ  . ARG C 1 143 ? 104.484 141.776 100.464 1.00 35.81  ? 143 ARG C CZ  1 
ATOM   8621  N NH1 . ARG C 1 143 ? 103.315 141.886 101.073 1.00 35.81  ? 143 ARG C NH1 1 
ATOM   8622  N NH2 . ARG C 1 143 ? 105.601 141.950 101.163 1.00 35.81  ? 143 ARG C NH2 1 
ATOM   8623  N N   . GLY C 1 144 ? 98.896  137.156 98.218  1.00 39.72  ? 144 GLY C N   1 
ATOM   8624  C CA  . GLY C 1 144 ? 97.569  136.819 97.766  1.00 39.72  ? 144 GLY C CA  1 
ATOM   8625  C C   . GLY C 1 144 ? 97.614  135.828 96.622  1.00 39.72  ? 144 GLY C C   1 
ATOM   8626  O O   . GLY C 1 144 ? 98.184  134.739 96.737  1.00 39.72  ? 144 GLY C O   1 
ATOM   8627  N N   . PRO C 1 145 ? 97.000  136.182 95.494  1.00 41.10  ? 145 PRO C N   1 
ATOM   8628  C CA  . PRO C 1 145 ? 97.063  135.305 94.317  1.00 41.10  ? 145 PRO C CA  1 
ATOM   8629  C C   . PRO C 1 145 ? 98.263  135.580 93.421  1.00 41.10  ? 145 PRO C C   1 
ATOM   8630  O O   . PRO C 1 145 ? 98.679  134.709 92.650  1.00 41.10  ? 145 PRO C O   1 
ATOM   8631  C CB  . PRO C 1 145 ? 95.745  135.601 93.591  1.00 41.10  ? 145 PRO C CB  1 
ATOM   8632  C CG  . PRO C 1 145 ? 95.299  136.955 94.090  1.00 41.10  ? 145 PRO C CG  1 
ATOM   8633  C CD  . PRO C 1 145 ? 96.142  137.357 95.270  1.00 41.10  ? 145 PRO C CD  1 
ATOM   8634  N N   . ALA C 1 146 ? 98.827  136.778 93.511  1.00 37.81  ? 146 ALA C N   1 
ATOM   8635  C CA  . ALA C 1 146 ? 99.887  137.203 92.610  1.00 37.81  ? 146 ALA C CA  1 
ATOM   8636  C C   . ALA C 1 146 ? 101.265 136.850 93.161  1.00 37.81  ? 146 ALA C C   1 
ATOM   8637  O O   . ALA C 1 146 ? 101.452 136.652 94.363  1.00 37.81  ? 146 ALA C O   1 
ATOM   8638  C CB  . ALA C 1 146 ? 99.801  138.707 92.356  1.00 37.81  ? 146 ALA C CB  1 
ATOM   8639  N N   . ASN C 1 147 ? 102.235 136.768 92.252  1.00 34.12  ? 147 ASN C N   1 
ATOM   8640  C CA  . ASN C 1 147 ? 103.627 136.600 92.643  1.00 34.12  ? 147 ASN C CA  1 
ATOM   8641  C C   . ASN C 1 147 ? 104.140 137.869 93.313  1.00 34.12  ? 147 ASN C C   1 
ATOM   8642  O O   . ASN C 1 147 ? 103.779 138.982 92.924  1.00 34.12  ? 147 ASN C O   1 
ATOM   8643  C CB  . ASN C 1 147 ? 104.489 136.268 91.423  1.00 34.12  ? 147 ASN C CB  1 
ATOM   8644  C CG  . ASN C 1 147 ? 104.255 134.863 90.903  1.00 34.12  ? 147 ASN C CG  1 
ATOM   8645  O OD1 . ASN C 1 147 ? 103.472 134.103 91.465  1.00 34.12  ? 147 ASN C OD1 1 
ATOM   8646  N ND2 . ASN C 1 147 ? 104.936 134.513 89.821  1.00 34.12  ? 147 ASN C ND2 1 
ATOM   8647  N N   . GLY C 1 148 ? 104.986 137.700 94.325  1.00 30.18  ? 148 GLY C N   1 
ATOM   8648  C CA  . GLY C 1 148 ? 105.503 138.840 95.056  1.00 30.18  ? 148 GLY C CA  1 
ATOM   8649  C C   . GLY C 1 148 ? 106.957 138.719 95.462  1.00 30.18  ? 148 GLY C C   1 
ATOM   8650  O O   . GLY C 1 148 ? 107.704 137.912 94.903  1.00 30.18  ? 148 GLY C O   1 
ATOM   8651  N N   . PHE C 1 149 ? 107.363 139.517 96.444  1.00 25.26  ? 149 PHE C N   1 
ATOM   8652  C CA  . PHE C 1 149 ? 108.754 139.613 96.868  1.00 25.26  ? 149 PHE C CA  1 
ATOM   8653  C C   . PHE C 1 149 ? 108.781 140.312 98.220  1.00 25.26  ? 149 PHE C C   1 
ATOM   8654  O O   . PHE C 1 149 ? 107.752 140.770 98.720  1.00 25.26  ? 149 PHE C O   1 
ATOM   8655  C CB  . PHE C 1 149 ? 109.594 140.371 95.835  1.00 25.26  ? 149 PHE C CB  1 
ATOM   8656  C CG  . PHE C 1 149 ? 111.064 140.093 95.917  1.00 25.26  ? 149 PHE C CG  1 
ATOM   8657  C CD1 . PHE C 1 149 ? 111.549 138.802 95.802  1.00 25.26  ? 149 PHE C CD1 1 
ATOM   8658  C CD2 . PHE C 1 149 ? 111.966 141.127 96.091  1.00 25.26  ? 149 PHE C CD2 1 
ATOM   8659  C CE1 . PHE C 1 149 ? 112.904 138.550 95.872  1.00 25.26  ? 149 PHE C CE1 1 
ATOM   8660  C CE2 . PHE C 1 149 ? 113.320 140.879 96.160  1.00 25.26  ? 149 PHE C CE2 1 
ATOM   8661  C CZ  . PHE C 1 149 ? 113.790 139.590 96.051  1.00 25.26  ? 149 PHE C CZ  1 
ATOM   8662  N N   . PHE C 1 150 ? 109.975 140.384 98.808  1.00 24.23  ? 150 PHE C N   1 
ATOM   8663  C CA  . PHE C 1 150 ? 110.161 141.137 100.042 1.00 24.23  ? 150 PHE C CA  1 
ATOM   8664  C C   . PHE C 1 150 ? 109.745 142.590 99.845  1.00 24.23  ? 150 PHE C C   1 
ATOM   8665  O O   . PHE C 1 150 ? 110.057 143.209 98.825  1.00 24.23  ? 150 PHE C O   1 
ATOM   8666  C CB  . PHE C 1 150 ? 111.621 141.070 100.493 1.00 24.23  ? 150 PHE C CB  1 
ATOM   8667  C CG  . PHE C 1 150 ? 112.118 139.676 100.750 1.00 24.23  ? 150 PHE C CG  1 
ATOM   8668  C CD1 . PHE C 1 150 ? 111.819 139.027 101.936 1.00 24.23  ? 150 PHE C CD1 1 
ATOM   8669  C CD2 . PHE C 1 150 ? 112.894 139.019 99.810  1.00 24.23  ? 150 PHE C CD2 1 
ATOM   8670  C CE1 . PHE C 1 150 ? 112.277 137.748 102.175 1.00 24.23  ? 150 PHE C CE1 1 
ATOM   8671  C CE2 . PHE C 1 150 ? 113.356 137.739 100.045 1.00 24.23  ? 150 PHE C CE2 1 
ATOM   8672  C CZ  . PHE C 1 150 ? 113.049 137.103 101.227 1.00 24.23  ? 150 PHE C CZ  1 
ATOM   8673  N N   . SER C 1 151 ? 109.038 143.139 100.835 1.00 25.32  ? 151 SER C N   1 
ATOM   8674  C CA  . SER C 1 151 ? 108.465 144.473 100.685 1.00 25.32  ? 151 SER C CA  1 
ATOM   8675  C C   . SER C 1 151 ? 109.511 145.581 100.739 1.00 25.32  ? 151 SER C C   1 
ATOM   8676  O O   . SER C 1 151 ? 109.259 146.672 100.221 1.00 25.32  ? 151 SER C O   1 
ATOM   8677  C CB  . SER C 1 151 ? 107.396 144.711 101.752 1.00 25.32  ? 151 SER C CB  1 
ATOM   8678  O OG  . SER C 1 151 ? 107.971 144.911 103.029 1.00 25.32  ? 151 SER C OG  1 
ATOM   8679  N N   . ARG C 1 152 ? 110.671 145.338 101.343 1.00 24.19  ? 152 ARG C N   1 
ATOM   8680  C CA  . ARG C 1 152 ? 111.694 146.366 101.484 1.00 24.19  ? 152 ARG C CA  1 
ATOM   8681  C C   . ARG C 1 152 ? 112.794 146.279 100.431 1.00 24.19  ? 152 ARG C C   1 
ATOM   8682  O O   . ARG C 1 152 ? 113.754 147.050 100.499 1.00 24.19  ? 152 ARG C O   1 
ATOM   8683  C CB  . ARG C 1 152 ? 112.319 146.305 102.883 1.00 24.19  ? 152 ARG C CB  1 
ATOM   8684  C CG  . ARG C 1 152 ? 111.328 146.452 104.032 1.00 24.19  ? 152 ARG C CG  1 
ATOM   8685  C CD  . ARG C 1 152 ? 110.522 147.740 103.941 1.00 24.19  ? 152 ARG C CD  1 
ATOM   8686  N NE  . ARG C 1 152 ? 109.845 148.041 105.196 1.00 24.19  ? 152 ARG C NE  1 
ATOM   8687  C CZ  . ARG C 1 152 ? 108.800 148.849 105.315 1.00 24.19  ? 152 ARG C CZ  1 
ATOM   8688  N NH1 . ARG C 1 152 ? 108.269 149.453 104.265 1.00 24.19  ? 152 ARG C NH1 1 
ATOM   8689  N NH2 . ARG C 1 152 ? 108.274 149.057 106.518 1.00 24.19  ? 152 ARG C NH2 1 
ATOM   8690  N N   . LEU C 1 153 ? 112.682 145.376 99.461  1.00 22.91  ? 153 LEU C N   1 
ATOM   8691  C CA  . LEU C 1 153 ? 113.703 145.202 98.439  1.00 22.91  ? 153 LEU C CA  1 
ATOM   8692  C C   . LEU C 1 153 ? 113.070 145.308 97.057  1.00 22.91  ? 153 LEU C C   1 
ATOM   8693  O O   . LEU C 1 153 ? 111.869 145.096 96.886  1.00 22.91  ? 153 LEU C O   1 
ATOM   8694  C CB  . LEU C 1 153 ? 114.432 143.860 98.600  1.00 22.91  ? 153 LEU C CB  1 
ATOM   8695  C CG  . LEU C 1 153 ? 115.162 143.640 99.930  1.00 22.91  ? 153 LEU C CG  1 
ATOM   8696  C CD1 . LEU C 1 153 ? 115.509 142.172 100.132 1.00 22.91  ? 153 LEU C CD1 1 
ATOM   8697  C CD2 . LEU C 1 153 ? 116.411 144.500 100.021 1.00 22.91  ? 153 LEU C CD2 1 
ATOM   8698  N N   . ASN C 1 154 ? 113.900 145.641 96.068  1.00 23.77  ? 154 ASN C N   1 
ATOM   8699  C CA  . ASN C 1 154 ? 113.457 145.900 94.700  1.00 23.77  ? 154 ASN C CA  1 
ATOM   8700  C C   . ASN C 1 154 ? 114.297 145.054 93.751  1.00 23.77  ? 154 ASN C C   1 
ATOM   8701  O O   . ASN C 1 154 ? 115.502 145.282 93.614  1.00 23.77  ? 154 ASN C O   1 
ATOM   8702  C CB  . ASN C 1 154 ? 113.576 147.391 94.372  1.00 23.77  ? 154 ASN C CB  1 
ATOM   8703  C CG  . ASN C 1 154 ? 112.855 147.778 93.098  1.00 23.77  ? 154 ASN C CG  1 
ATOM   8704  O OD1 . ASN C 1 154 ? 112.200 146.956 92.464  1.00 23.77  ? 154 ASN C OD1 1 
ATOM   8705  N ND2 . ASN C 1 154 ? 112.971 149.041 92.718  1.00 23.77  ? 154 ASN C ND2 1 
ATOM   8706  N N   . TRP C 1 155 ? 113.666 144.078 93.101  1.00 26.41  ? 155 TRP C N   1 
ATOM   8707  C CA  . TRP C 1 155 ? 114.354 143.135 92.223  1.00 26.41  ? 155 TRP C CA  1 
ATOM   8708  C C   . TRP C 1 155 ? 114.379 143.701 90.805  1.00 26.41  ? 155 TRP C C   1 
ATOM   8709  O O   . TRP C 1 155 ? 113.334 143.827 90.162  1.00 26.41  ? 155 TRP C O   1 
ATOM   8710  C CB  . TRP C 1 155 ? 113.662 141.774 92.265  1.00 26.41  ? 155 TRP C CB  1 
ATOM   8711  C CG  . TRP C 1 155 ? 114.426 140.648 91.626  1.00 26.41  ? 155 TRP C CG  1 
ATOM   8712  C CD1 . TRP C 1 155 ? 115.557 140.744 90.869  1.00 26.41  ? 155 TRP C CD1 1 
ATOM   8713  C CD2 . TRP C 1 155 ? 114.106 139.254 91.689  1.00 26.41  ? 155 TRP C CD2 1 
ATOM   8714  N NE1 . TRP C 1 155 ? 115.961 139.500 90.459  1.00 26.41  ? 155 TRP C NE1 1 
ATOM   8715  C CE2 . TRP C 1 155 ? 115.086 138.566 90.949  1.00 26.41  ? 155 TRP C CE2 1 
ATOM   8716  C CE3 . TRP C 1 155 ? 113.085 138.520 92.300  1.00 26.41  ? 155 TRP C CE3 1 
ATOM   8717  C CZ2 . TRP C 1 155 ? 115.078 137.181 90.806  1.00 26.41  ? 155 TRP C CZ2 1 
ATOM   8718  C CZ3 . TRP C 1 155 ? 113.077 137.147 92.156  1.00 26.41  ? 155 TRP C CZ3 1 
ATOM   8719  C CH2 . TRP C 1 155 ? 114.068 136.491 91.415  1.00 26.41  ? 155 TRP C CH2 1 
ATOM   8720  N N   . LEU C 1 156 ? 115.573 144.022 90.312  1.00 26.90  ? 156 LEU C N   1 
ATOM   8721  C CA  . LEU C 1 156 ? 115.751 144.647 89.007  1.00 26.90  ? 156 LEU C CA  1 
ATOM   8722  C C   . LEU C 1 156 ? 116.183 143.609 87.978  1.00 26.90  ? 156 LEU C C   1 
ATOM   8723  O O   . LEU C 1 156 ? 117.062 142.787 88.253  1.00 26.90  ? 156 LEU C O   1 
ATOM   8724  C CB  . LEU C 1 156 ? 116.789 145.770 89.077  1.00 26.90  ? 156 LEU C CB  1 
ATOM   8725  C CG  . LEU C 1 156 ? 116.692 146.829 90.179  1.00 26.90  ? 156 LEU C CG  1 
ATOM   8726  C CD1 . LEU C 1 156 ? 117.899 147.751 90.134  1.00 26.90  ? 156 LEU C CD1 1 
ATOM   8727  C CD2 . LEU C 1 156 ? 115.404 147.631 90.075  1.00 26.90  ? 156 LEU C CD2 1 
ATOM   8728  N N   . THR C 1 157 ? 115.564 143.650 86.798  1.00 29.91  ? 157 THR C N   1 
ATOM   8729  C CA  . THR C 1 157 ? 115.932 142.799 85.671  1.00 29.91  ? 157 THR C CA  1 
ATOM   8730  C C   . THR C 1 157 ? 116.043 143.654 84.411  1.00 29.91  ? 157 THR C C   1 
ATOM   8731  O O   . THR C 1 157 ? 115.823 144.867 84.434  1.00 29.91  ? 157 THR C O   1 
ATOM   8732  C CB  . THR C 1 157 ? 114.924 141.656 85.460  1.00 29.91  ? 157 THR C CB  1 
ATOM   8733  O OG1 . THR C 1 157 ? 113.629 142.192 85.168  1.00 29.91  ? 157 THR C OG1 1 
ATOM   8734  C CG2 . THR C 1 157 ? 114.844 140.759 86.690  1.00 29.91  ? 157 THR C CG2 1 
ATOM   8735  N N   . LYS C 1 158 ? 116.384 143.005 83.300  1.00 32.52  ? 158 LYS C N   1 
ATOM   8736  C CA  . LYS C 1 158 ? 116.603 143.710 82.045  1.00 32.52  ? 158 LYS C CA  1 
ATOM   8737  C C   . LYS C 1 158 ? 115.315 144.344 81.529  1.00 32.52  ? 158 LYS C C   1 
ATOM   8738  O O   . LYS C 1 158 ? 114.206 143.888 81.819  1.00 32.52  ? 158 LYS C O   1 
ATOM   8739  C CB  . LYS C 1 158 ? 117.164 142.756 80.989  1.00 32.52  ? 158 LYS C CB  1 
ATOM   8740  C CG  . LYS C 1 158 ? 116.109 141.880 80.339  1.00 32.52  ? 158 LYS C CG  1 
ATOM   8741  C CD  . LYS C 1 158 ? 116.674 141.033 79.219  1.00 32.52  ? 158 LYS C CD  1 
ATOM   8742  C CE  . LYS C 1 158 ? 115.626 140.059 78.706  1.00 32.52  ? 158 LYS C CE  1 
ATOM   8743  N NZ  . LYS C 1 158 ? 116.186 139.096 77.726  1.00 32.52  ? 158 LYS C NZ  1 
ATOM   8744  N N   . SER C 1 159 ? 115.475 145.417 80.761  1.00 35.19  ? 159 SER C N   1 
ATOM   8745  C CA  . SER C 1 159 ? 114.369 146.090 80.091  1.00 35.19  ? 159 SER C CA  1 
ATOM   8746  C C   . SER C 1 159 ? 114.589 145.983 78.591  1.00 35.19  ? 159 SER C C   1 
ATOM   8747  O O   . SER C 1 159 ? 115.598 146.470 78.072  1.00 35.19  ? 159 SER C O   1 
ATOM   8748  C CB  . SER C 1 159 ? 114.268 147.555 80.520  1.00 35.19  ? 159 SER C CB  1 
ATOM   8749  O OG  . SER C 1 159 ? 113.158 148.187 79.911  1.00 35.19  ? 159 SER C OG  1 
ATOM   8750  N N   . GLY C 1 160 ? 113.648 145.350 77.898  1.00 37.11  ? 160 GLY C N   1 
ATOM   8751  C CA  . GLY C 1 160 ? 113.816 145.100 76.482  1.00 37.11  ? 160 GLY C CA  1 
ATOM   8752  C C   . GLY C 1 160 ? 114.873 144.050 76.222  1.00 37.11  ? 160 GLY C C   1 
ATOM   8753  O O   . GLY C 1 160 ? 114.663 142.866 76.501  1.00 37.11  ? 160 GLY C O   1 
ATOM   8754  N N   . SER C 1 161 ? 116.023 144.470 75.691  1.00 37.51  ? 161 SER C N   1 
ATOM   8755  C CA  . SER C 1 161 ? 117.130 143.556 75.439  1.00 37.51  ? 161 SER C CA  1 
ATOM   8756  C C   . SER C 1 161 ? 118.441 144.059 76.034  1.00 37.51  ? 161 SER C C   1 
ATOM   8757  O O   . SER C 1 161 ? 119.511 143.596 75.631  1.00 37.51  ? 161 SER C O   1 
ATOM   8758  C CB  . SER C 1 161 ? 117.295 143.313 73.937  1.00 37.51  ? 161 SER C CB  1 
ATOM   8759  O OG  . SER C 1 161 ? 117.943 144.407 73.313  1.00 37.51  ? 161 SER C OG  1 
ATOM   8760  N N   . SER C 1 162 ? 118.389 144.988 76.986  1.00 34.94  ? 162 SER C N   1 
ATOM   8761  C CA  . SER C 1 162 ? 119.603 145.568 77.539  1.00 34.94  ? 162 SER C CA  1 
ATOM   8762  C C   . SER C 1 162 ? 119.482 145.719 79.048  1.00 34.94  ? 162 SER C C   1 
ATOM   8763  O O   . SER C 1 162 ? 118.391 145.911 79.589  1.00 34.94  ? 162 SER C O   1 
ATOM   8764  C CB  . SER C 1 162 ? 119.911 146.931 76.905  1.00 34.94  ? 162 SER C CB  1 
ATOM   8765  O OG  . SER C 1 162 ? 118.886 147.866 77.185  1.00 34.94  ? 162 SER C OG  1 
ATOM   8766  N N   . TYR C 1 163 ? 120.628 145.626 79.720  1.00 30.94  ? 163 TYR C N   1 
ATOM   8767  C CA  . TYR C 1 163 ? 120.757 145.897 81.151  1.00 30.94  ? 163 TYR C CA  1 
ATOM   8768  C C   . TYR C 1 163 ? 121.951 146.829 81.298  1.00 30.94  ? 163 TYR C C   1 
ATOM   8769  O O   . TYR C 1 163 ? 123.101 146.376 81.370  1.00 30.94  ? 163 TYR C O   1 
ATOM   8770  C CB  . TYR C 1 163 ? 120.930 144.606 81.951  1.00 30.94  ? 163 TYR C CB  1 
ATOM   8771  C CG  . TYR C 1 163 ? 120.868 144.763 83.460  1.00 30.94  ? 163 TYR C CG  1 
ATOM   8772  C CD1 . TYR C 1 163 ? 121.876 145.413 84.158  1.00 30.94  ? 163 TYR C CD1 1 
ATOM   8773  C CD2 . TYR C 1 163 ? 119.806 144.244 84.186  1.00 30.94  ? 163 TYR C CD2 1 
ATOM   8774  C CE1 . TYR C 1 163 ? 121.823 145.553 85.531  1.00 30.94  ? 163 TYR C CE1 1 
ATOM   8775  C CE2 . TYR C 1 163 ? 119.746 144.375 85.560  1.00 30.94  ? 163 TYR C CE2 1 
ATOM   8776  C CZ  . TYR C 1 163 ? 120.757 145.030 86.227  1.00 30.94  ? 163 TYR C CZ  1 
ATOM   8777  O OH  . TYR C 1 163 ? 120.702 145.164 87.592  1.00 30.94  ? 163 TYR C OH  1 
ATOM   8778  N N   . PRO C 1 164 ? 121.720 148.138 81.342  1.00 32.36  ? 164 PRO C N   1 
ATOM   8779  C CA  . PRO C 1 164 ? 122.835 149.090 81.337  1.00 32.36  ? 164 PRO C CA  1 
ATOM   8780  C C   . PRO C 1 164 ? 123.542 149.131 82.683  1.00 32.36  ? 164 PRO C C   1 
ATOM   8781  O O   . PRO C 1 164 ? 123.090 148.571 83.682  1.00 32.36  ? 164 PRO C O   1 
ATOM   8782  C CB  . PRO C 1 164 ? 122.163 150.432 81.021  1.00 32.36  ? 164 PRO C CB  1 
ATOM   8783  C CG  . PRO C 1 164 ? 120.697 150.119 80.792  1.00 32.36  ? 164 PRO C CG  1 
ATOM   8784  C CD  . PRO C 1 164 ? 120.429 148.824 81.471  1.00 32.36  ? 164 PRO C CD  1 
ATOM   8785  N N   . LEU C 1 165 ? 124.680 149.816 82.693  1.00 30.08  ? 165 LEU C N   1 
ATOM   8786  C CA  . LEU C 1 165 ? 125.450 149.985 83.918  1.00 30.08  ? 165 LEU C CA  1 
ATOM   8787  C C   . LEU C 1 165 ? 124.749 150.976 84.841  1.00 30.08  ? 165 LEU C C   1 
ATOM   8788  O O   . LEU C 1 165 ? 124.515 152.129 84.464  1.00 30.08  ? 165 LEU C O   1 
ATOM   8789  C CB  . LEU C 1 165 ? 126.863 150.458 83.589  1.00 30.08  ? 165 LEU C CB  1 
ATOM   8790  C CG  . LEU C 1 165 ? 127.753 150.871 84.762  1.00 30.08  ? 165 LEU C CG  1 
ATOM   8791  C CD1 . LEU C 1 165 ? 128.167 149.667 85.589  1.00 30.08  ? 165 LEU C CD1 1 
ATOM   8792  C CD2 . LEU C 1 165 ? 128.973 151.621 84.261  1.00 30.08  ? 165 LEU C CD2 1 
ATOM   8793  N N   . LEU C 1 166 ? 124.415 150.528 86.047  1.00 29.11  ? 166 LEU C N   1 
ATOM   8794  C CA  . LEU C 1 166 ? 123.730 151.359 87.026  1.00 29.11  ? 166 LEU C CA  1 
ATOM   8795  C C   . LEU C 1 166 ? 124.749 152.051 87.922  1.00 29.11  ? 166 LEU C C   1 
ATOM   8796  O O   . LEU C 1 166 ? 125.684 151.411 88.415  1.00 29.11  ? 166 LEU C O   1 
ATOM   8797  C CB  . LEU C 1 166 ? 122.771 150.519 87.869  1.00 29.11  ? 166 LEU C CB  1 
ATOM   8798  C CG  . LEU C 1 166 ? 121.637 149.814 87.125  1.00 29.11  ? 166 LEU C CG  1 
ATOM   8799  C CD1 . LEU C 1 166 ? 121.010 148.750 88.005  1.00 29.11  ? 166 LEU C CD1 1 
ATOM   8800  C CD2 . LEU C 1 166 ? 120.596 150.816 86.663  1.00 29.11  ? 166 LEU C CD2 1 
ATOM   8801  N N   . ASN C 1 167 ? 124.547 153.353 88.140  1.00 29.21  ? 167 ASN C N   1 
ATOM   8802  C CA  . ASN C 1 167 ? 125.467 154.187 88.915  1.00 29.21  ? 167 ASN C CA  1 
ATOM   8803  C C   . ASN C 1 167 ? 124.628 155.258 89.609  1.00 29.21  ? 167 ASN C C   1 
ATOM   8804  O O   . ASN C 1 167 ? 124.289 156.271 88.992  1.00 29.21  ? 167 ASN C O   1 
ATOM   8805  C CB  . ASN C 1 167 ? 126.531 154.802 88.011  1.00 29.21  ? 167 ASN C CB  1 
ATOM   8806  C CG  . ASN C 1 167 ? 127.634 155.501 88.785  1.00 29.21  ? 167 ASN C CG  1 
ATOM   8807  O OD1 . ASN C 1 167 ? 128.259 154.912 89.663  1.00 29.21  ? 167 ASN C OD1 1 
ATOM   8808  N ND2 . ASN C 1 167 ? 127.878 156.769 88.455  1.00 29.21  ? 167 ASN C ND2 1 
ATOM   8809  N N   . VAL C 1 168 ? 124.294 155.034 90.882  1.00 27.43  ? 168 VAL C N   1 
ATOM   8810  C CA  . VAL C 1 168 ? 123.425 155.948 91.613  1.00 27.43  ? 168 VAL C CA  1 
ATOM   8811  C C   . VAL C 1 168 ? 124.083 156.350 92.927  1.00 27.43  ? 168 VAL C C   1 
ATOM   8812  O O   . VAL C 1 168 ? 124.935 155.644 93.471  1.00 27.43  ? 168 VAL C O   1 
ATOM   8813  C CB  . VAL C 1 168 ? 122.023 155.353 91.879  1.00 27.43  ? 168 VAL C CB  1 
ATOM   8814  C CG1 . VAL C 1 168 ? 121.424 154.793 90.601  1.00 27.43  ? 168 VAL C CG1 1 
ATOM   8815  C CG2 . VAL C 1 168 ? 122.089 154.286 92.955  1.00 27.43  ? 168 VAL C CG2 1 
ATOM   8816  N N   . THR C 1 169 ? 123.664 157.508 93.437  1.00 29.84  ? 169 THR C N   1 
ATOM   8817  C CA  . THR C 1 169 ? 124.232 158.084 94.646  1.00 29.84  ? 169 THR C CA  1 
ATOM   8818  C C   . THR C 1 169 ? 123.124 158.658 95.520  1.00 29.84  ? 169 THR C C   1 
ATOM   8819  O O   . THR C 1 169 ? 122.088 159.106 95.026  1.00 29.84  ? 169 THR C O   1 
ATOM   8820  C CB  . THR C 1 169 ? 125.268 159.171 94.313  1.00 29.84  ? 169 THR C CB  1 
ATOM   8821  O OG1 . THR C 1 169 ? 125.717 159.800 95.519  1.00 29.84  ? 169 THR C OG1 1 
ATOM   8822  C CG2 . THR C 1 169 ? 124.672 160.217 93.395  1.00 29.84  ? 169 THR C CG2 1 
ATOM   8823  N N   . MET C 1 170 ? 123.355 158.627 96.830  1.00 30.59  ? 170 MET C N   1 
ATOM   8824  C CA  . MET C 1 170 ? 122.433 159.157 97.827  1.00 30.59  ? 170 MET C CA  1 
ATOM   8825  C C   . MET C 1 170 ? 123.214 159.707 99.015  1.00 30.59  ? 170 MET C C   1 
ATOM   8826  O O   . MET C 1 170 ? 123.915 158.954 99.701  1.00 30.59  ? 170 MET C O   1 
ATOM   8827  C CB  . MET C 1 170 ? 121.444 158.080 98.280  1.00 30.59  ? 170 MET C CB  1 
ATOM   8828  C CG  . MET C 1 170 ? 120.168 158.614 98.930  1.00 30.59  ? 170 MET C CG  1 
ATOM   8829  S SD  . MET C 1 170 ? 119.043 159.471 97.809  1.00 30.59  ? 170 MET C SD  1 
ATOM   8830  C CE  . MET C 1 170 ? 118.198 158.099 97.031  1.00 30.59  ? 170 MET C CE  1 
ATOM   8831  N N   . PRO C 1 171 ? 123.141 161.008 99.277  1.00 30.99  ? 171 PRO C N   1 
ATOM   8832  C CA  . PRO C 1 171 ? 123.863 161.585 100.412 1.00 30.99  ? 171 PRO C CA  1 
ATOM   8833  C C   . PRO C 1 171 ? 123.059 161.537 101.700 1.00 30.99  ? 171 PRO C C   1 
ATOM   8834  O O   . PRO C 1 171 ? 121.828 161.500 101.704 1.00 30.99  ? 171 PRO C O   1 
ATOM   8835  C CB  . PRO C 1 171 ? 124.097 163.039 99.974  1.00 30.99  ? 171 PRO C CB  1 
ATOM   8836  C CG  . PRO C 1 171 ? 123.171 163.279 98.802  1.00 30.99  ? 171 PRO C CG  1 
ATOM   8837  C CD  . PRO C 1 171 ? 122.398 162.029 98.523  1.00 30.99  ? 171 PRO C CD  1 
ATOM   8838  N N   . ASN C 1 172 ? 123.786 161.539 102.812 1.00 31.20  ? 172 ASN C N   1 
ATOM   8839  C CA  . ASN C 1 172 ? 123.191 161.606 104.144 1.00 31.20  ? 172 ASN C CA  1 
ATOM   8840  C C   . ASN C 1 172 ? 123.289 163.050 104.628 1.00 31.20  ? 172 ASN C C   1 
ATOM   8841  O O   . ASN C 1 172 ? 124.341 163.490 105.096 1.00 31.20  ? 172 ASN C O   1 
ATOM   8842  C CB  . ASN C 1 172 ? 123.884 160.644 105.103 1.00 31.20  ? 172 ASN C CB  1 
ATOM   8843  C CG  . ASN C 1 172 ? 123.174 160.539 106.441 1.00 31.20  ? 172 ASN C CG  1 
ATOM   8844  O OD1 . ASN C 1 172 ? 122.222 161.265 106.712 1.00 31.20  ? 172 ASN C OD1 1 
ATOM   8845  N ND2 . ASN C 1 172 ? 123.634 159.625 107.282 1.00 31.20  ? 172 ASN C ND2 1 
ATOM   8846  N N   . ASN C 1 173 ? 122.184 163.784 104.523 1.00 35.70  ? 173 ASN C N   1 
ATOM   8847  C CA  . ASN C 1 173 ? 122.123 165.173 104.954 1.00 35.70  ? 173 ASN C CA  1 
ATOM   8848  C C   . ASN C 1 173 ? 121.406 165.336 106.289 1.00 35.70  ? 173 ASN C C   1 
ATOM   8849  O O   . ASN C 1 173 ? 121.035 166.456 106.654 1.00 35.70  ? 173 ASN C O   1 
ATOM   8850  C CB  . ASN C 1 173 ? 121.456 166.030 103.878 1.00 35.70  ? 173 ASN C CB  1 
ATOM   8851  C CG  . ASN C 1 173 ? 122.378 166.315 102.710 1.00 35.70  ? 173 ASN C CG  1 
ATOM   8852  O OD1 . ASN C 1 173 ? 123.560 166.600 102.895 1.00 35.70  ? 173 ASN C OD1 1 
ATOM   8853  N ND2 . ASN C 1 173 ? 121.841 166.244 101.500 1.00 35.70  ? 173 ASN C ND2 1 
ATOM   8854  N N   . TYR C 1 174 ? 121.197 164.243 107.016 1.00 35.95  ? 174 TYR C N   1 
ATOM   8855  C CA  . TYR C 1 174 ? 120.594 164.276 108.338 1.00 35.95  ? 174 TYR C CA  1 
ATOM   8856  C C   . TYR C 1 174 ? 121.696 164.312 109.394 1.00 35.95  ? 174 TYR C C   1 
ATOM   8857  O O   . TYR C 1 174 ? 122.884 164.429 109.082 1.00 35.95  ? 174 TYR C O   1 
ATOM   8858  C CB  . TYR C 1 174 ? 119.674 163.074 108.526 1.00 35.95  ? 174 TYR C CB  1 
ATOM   8859  C CG  . TYR C 1 174 ? 118.535 163.009 107.539 1.00 35.95  ? 174 TYR C CG  1 
ATOM   8860  C CD1 . TYR C 1 174 ? 117.858 164.156 107.158 1.00 35.95  ? 174 TYR C CD1 1 
ATOM   8861  C CD2 . TYR C 1 174 ? 118.150 161.803 106.976 1.00 35.95  ? 174 TYR C CD2 1 
ATOM   8862  C CE1 . TYR C 1 174 ? 116.819 164.102 106.254 1.00 35.95  ? 174 TYR C CE1 1 
ATOM   8863  C CE2 . TYR C 1 174 ? 117.115 161.738 106.070 1.00 35.95  ? 174 TYR C CE2 1 
ATOM   8864  C CZ  . TYR C 1 174 ? 116.452 162.890 105.713 1.00 35.95  ? 174 TYR C CZ  1 
ATOM   8865  O OH  . TYR C 1 174 ? 115.417 162.834 104.810 1.00 35.95  ? 174 TYR C OH  1 
ATOM   8866  N N   . ASN C 1 175 ? 121.314 164.198 110.666 1.00 37.87  ? 175 ASN C N   1 
ATOM   8867  C CA  . ASN C 1 175 ? 122.273 164.160 111.763 1.00 37.87  ? 175 ASN C CA  1 
ATOM   8868  C C   . ASN C 1 175 ? 122.240 162.830 112.511 1.00 37.87  ? 175 ASN C C   1 
ATOM   8869  O O   . ASN C 1 175 ? 122.707 162.754 113.650 1.00 37.87  ? 175 ASN C O   1 
ATOM   8870  C CB  . ASN C 1 175 ? 122.036 165.324 112.728 1.00 37.87  ? 175 ASN C CB  1 
ATOM   8871  C CG  . ASN C 1 175 ? 120.598 165.416 113.191 1.00 37.87  ? 175 ASN C CG  1 
ATOM   8872  O OD1 . ASN C 1 175 ? 119.692 164.886 112.551 1.00 37.87  ? 175 ASN C OD1 1 
ATOM   8873  N ND2 . ASN C 1 175 ? 120.382 166.092 114.313 1.00 37.87  ? 175 ASN C ND2 1 
ATOM   8874  N N   . PHE C 1 176 ? 121.699 161.781 111.896 1.00 33.63  ? 176 PHE C N   1 
ATOM   8875  C CA  . PHE C 1 176 ? 121.715 160.440 112.461 1.00 33.63  ? 176 PHE C CA  1 
ATOM   8876  C C   . PHE C 1 176 ? 122.228 159.457 111.415 1.00 33.63  ? 176 PHE C C   1 
ATOM   8877  O O   . PHE C 1 176 ? 122.371 159.788 110.236 1.00 33.63  ? 176 PHE C O   1 
ATOM   8878  C CB  . PHE C 1 176 ? 120.326 160.021 112.972 1.00 33.63  ? 176 PHE C CB  1 
ATOM   8879  C CG  . PHE C 1 176 ? 119.211 160.257 111.990 1.00 33.63  ? 176 PHE C CG  1 
ATOM   8880  C CD1 . PHE C 1 176 ? 118.993 159.379 110.941 1.00 33.63  ? 176 PHE C CD1 1 
ATOM   8881  C CD2 . PHE C 1 176 ? 118.373 161.349 112.125 1.00 33.63  ? 176 PHE C CD2 1 
ATOM   8882  C CE1 . PHE C 1 176 ? 117.968 159.592 110.042 1.00 33.63  ? 176 PHE C CE1 1 
ATOM   8883  C CE2 . PHE C 1 176 ? 117.344 161.566 111.229 1.00 33.63  ? 176 PHE C CE2 1 
ATOM   8884  C CZ  . PHE C 1 176 ? 117.142 160.687 110.187 1.00 33.63  ? 176 PHE C CZ  1 
ATOM   8885  N N   . ASP C 1 177 ? 122.512 158.237 111.865 1.00 31.59  ? 177 ASP C N   1 
ATOM   8886  C CA  . ASP C 1 177 ? 123.050 157.196 110.999 1.00 31.59  ? 177 ASP C CA  1 
ATOM   8887  C C   . ASP C 1 177 ? 121.945 156.532 110.184 1.00 31.59  ? 177 ASP C C   1 
ATOM   8888  O O   . ASP C 1 177 ? 120.796 156.431 110.621 1.00 31.59  ? 177 ASP C O   1 
ATOM   8889  C CB  . ASP C 1 177 ? 123.773 156.132 111.824 1.00 31.59  ? 177 ASP C CB  1 
ATOM   8890  C CG  . ASP C 1 177 ? 125.124 156.592 112.325 1.00 31.59  ? 177 ASP C CG  1 
ATOM   8891  O OD1 . ASP C 1 177 ? 125.450 157.784 112.165 1.00 31.59  ? 177 ASP C OD1 1 
ATOM   8892  O OD2 . ASP C 1 177 ? 125.862 155.758 112.888 1.00 31.59  ? 177 ASP C OD2 1 
ATOM   8893  N N   . LYS C 1 178 ? 122.308 156.065 108.993 1.00 25.59  ? 178 LYS C N   1 
ATOM   8894  C CA  . LYS C 1 178 ? 121.397 155.339 108.118 1.00 25.59  ? 178 LYS C CA  1 
ATOM   8895  C C   . LYS C 1 178 ? 121.866 153.901 107.950 1.00 25.59  ? 178 LYS C C   1 
ATOM   8896  O O   . LYS C 1 178 ? 123.065 153.645 107.817 1.00 25.59  ? 178 LYS C O   1 
ATOM   8897  C CB  . LYS C 1 178 ? 121.300 155.999 106.741 1.00 25.59  ? 178 LYS C CB  1 
ATOM   8898  C CG  . LYS C 1 178 ? 120.551 157.313 106.701 1.00 25.59  ? 178 LYS C CG  1 
ATOM   8899  C CD  . LYS C 1 178 ? 120.701 157.950 105.333 1.00 25.59  ? 178 LYS C CD  1 
ATOM   8900  C CE  . LYS C 1 178 ? 119.751 159.109 105.136 1.00 25.59  ? 178 LYS C CE  1 
ATOM   8901  N NZ  . LYS C 1 178 ? 119.795 159.619 103.741 1.00 25.59  ? 178 LYS C NZ  1 
ATOM   8902  N N   . LEU C 1 179 ? 120.920 152.967 107.951 1.00 23.79  ? 179 LEU C N   1 
ATOM   8903  C CA  . LEU C 1 179 ? 121.194 151.557 107.702 1.00 23.79  ? 179 LEU C CA  1 
ATOM   8904  C C   . LEU C 1 179 ? 120.511 151.129 106.411 1.00 23.79  ? 179 LEU C C   1 
ATOM   8905  O O   . LEU C 1 179 ? 119.298 151.300 106.261 1.00 23.79  ? 179 LEU C O   1 
ATOM   8906  C CB  . LEU C 1 179 ? 120.715 150.689 108.869 1.00 23.79  ? 179 LEU C CB  1 
ATOM   8907  C CG  . LEU C 1 179 ? 120.862 149.170 108.725 1.00 23.79  ? 179 LEU C CG  1 
ATOM   8908  C CD1 . LEU C 1 179 ? 122.321 148.750 108.728 1.00 23.79  ? 179 LEU C CD1 1 
ATOM   8909  C CD2 . LEU C 1 179 ? 120.102 148.455 109.822 1.00 23.79  ? 179 LEU C CD2 1 
ATOM   8910  N N   . TYR C 1 180 ? 121.286 150.569 105.487 1.00 22.47  ? 180 TYR C N   1 
ATOM   8911  C CA  . TYR C 1 180 ? 120.786 150.094 104.205 1.00 22.47  ? 180 TYR C CA  1 
ATOM   8912  C C   . TYR C 1 180 ? 120.947 148.583 104.132 1.00 22.47  ? 180 TYR C C   1 
ATOM   8913  O O   . TYR C 1 180 ? 122.010 148.052 104.470 1.00 22.47  ? 180 TYR C O   1 
ATOM   8914  C CB  . TYR C 1 180 ? 121.535 150.752 103.043 1.00 22.47  ? 180 TYR C CB  1 
ATOM   8915  C CG  . TYR C 1 180 ? 121.174 152.197 102.786 1.00 22.47  ? 180 TYR C CG  1 
ATOM   8916  C CD1 . TYR C 1 180 ? 120.081 152.532 102.000 1.00 22.47  ? 180 TYR C CD1 1 
ATOM   8917  C CD2 . TYR C 1 180 ? 121.937 153.227 103.316 1.00 22.47  ? 180 TYR C CD2 1 
ATOM   8918  C CE1 . TYR C 1 180 ? 119.753 153.850 101.760 1.00 22.47  ? 180 TYR C CE1 1 
ATOM   8919  C CE2 . TYR C 1 180 ? 121.618 154.547 103.080 1.00 22.47  ? 180 TYR C CE2 1 
ATOM   8920  C CZ  . TYR C 1 180 ? 120.527 154.853 102.301 1.00 22.47  ? 180 TYR C CZ  1 
ATOM   8921  O OH  . TYR C 1 180 ? 120.207 156.168 102.064 1.00 22.47  ? 180 TYR C OH  1 
ATOM   8922  N N   . ILE C 1 181 ? 119.895 147.899 103.687 1.00 21.33  ? 181 ILE C N   1 
ATOM   8923  C CA  . ILE C 1 181 ? 119.909 146.461 103.443 1.00 21.33  ? 181 ILE C CA  1 
ATOM   8924  C C   . ILE C 1 181 ? 119.768 146.237 101.943 1.00 21.33  ? 181 ILE C C   1 
ATOM   8925  O O   . ILE C 1 181 ? 118.876 146.809 101.308 1.00 21.33  ? 181 ILE C O   1 
ATOM   8926  C CB  . ILE C 1 181 ? 118.784 145.743 104.211 1.00 21.33  ? 181 ILE C CB  1 
ATOM   8927  C CG1 . ILE C 1 181 ? 118.711 146.233 105.660 1.00 21.33  ? 181 ILE C CG1 1 
ATOM   8928  C CG2 . ILE C 1 181 ? 118.972 144.234 104.153 1.00 21.33  ? 181 ILE C CG2 1 
ATOM   8929  C CD1 . ILE C 1 181 ? 119.875 145.811 106.516 1.00 21.33  ? 181 ILE C CD1 1 
ATOM   8930  N N   . TRP C 1 182 ? 120.646 145.412 101.375 1.00 20.76  ? 182 TRP C N   1 
ATOM   8931  C CA  . TRP C 1 182 ? 120.612 145.134 99.945  1.00 20.76  ? 182 TRP C CA  1 
ATOM   8932  C C   . TRP C 1 182 ? 121.014 143.683 99.720  1.00 20.76  ? 182 TRP C C   1 
ATOM   8933  O O   . TRP C 1 182 ? 121.373 142.968 100.655 1.00 20.76  ? 182 TRP C O   1 
ATOM   8934  C CB  . TRP C 1 182 ? 121.509 146.107 99.164  1.00 20.76  ? 182 TRP C CB  1 
ATOM   8935  C CG  . TRP C 1 182 ? 122.871 146.300 99.749  1.00 20.76  ? 182 TRP C CG  1 
ATOM   8936  C CD1 . TRP C 1 182 ? 123.208 147.117 100.787 1.00 20.76  ? 182 TRP C CD1 1 
ATOM   8937  C CD2 . TRP C 1 182 ? 124.085 145.675 99.322  1.00 20.76  ? 182 TRP C CD2 1 
ATOM   8938  N NE1 . TRP C 1 182 ? 124.551 147.034 101.040 1.00 20.76  ? 182 TRP C NE1 1 
ATOM   8939  C CE2 . TRP C 1 182 ? 125.115 146.155 100.153 1.00 20.76  ? 182 TRP C CE2 1 
ATOM   8940  C CE3 . TRP C 1 182 ? 124.400 144.750 98.322  1.00 20.76  ? 182 TRP C CE3 1 
ATOM   8941  C CZ2 . TRP C 1 182 ? 126.437 145.743 100.015 1.00 20.76  ? 182 TRP C CZ2 1 
ATOM   8942  C CZ3 . TRP C 1 182 ? 125.711 144.345 98.185  1.00 20.76  ? 182 TRP C CZ3 1 
ATOM   8943  C CH2 . TRP C 1 182 ? 126.714 144.839 99.027  1.00 20.76  ? 182 TRP C CH2 1 
ATOM   8944  N N   . GLY C 1 183 ? 120.937 143.239 98.464  1.00 22.06  ? 183 GLY C N   1 
ATOM   8945  C CA  . GLY C 1 183 ? 121.198 141.843 98.175  1.00 22.06  ? 183 GLY C CA  1 
ATOM   8946  C C   . GLY C 1 183 ? 121.743 141.590 96.785  1.00 22.06  ? 183 GLY C C   1 
ATOM   8947  O O   . GLY C 1 183 ? 121.764 142.468 95.922  1.00 22.06  ? 183 GLY C O   1 
ATOM   8948  N N   . VAL C 1 184 ? 122.192 140.351 96.593  1.00 23.69  ? 184 VAL C N   1 
ATOM   8949  C CA  . VAL C 1 184 ? 122.715 139.858 95.322  1.00 23.69  ? 184 VAL C CA  1 
ATOM   8950  C C   . VAL C 1 184 ? 122.015 138.545 94.993  1.00 23.69  ? 184 VAL C C   1 
ATOM   8951  O O   . VAL C 1 184 ? 121.841 137.693 95.868  1.00 23.69  ? 184 VAL C O   1 
ATOM   8952  C CB  . VAL C 1 184 ? 124.248 139.656 95.372  1.00 23.69  ? 184 VAL C CB  1 
ATOM   8953  C CG1 . VAL C 1 184 ? 124.786 139.242 94.010  1.00 23.69  ? 184 VAL C CG1 1 
ATOM   8954  C CG2 . VAL C 1 184 ? 124.949 140.912 95.871  1.00 23.69  ? 184 VAL C CG2 1 
ATOM   8955  N N   . HIS C 1 185 ? 121.617 138.376 93.734  1.00 24.83  ? 185 HIS C N   1 
ATOM   8956  C CA  . HIS C 1 185 ? 120.920 137.172 93.291  1.00 24.83  ? 185 HIS C CA  1 
ATOM   8957  C C   . HIS C 1 185 ? 121.893 136.186 92.653  1.00 24.83  ? 185 HIS C C   1 
ATOM   8958  O O   . HIS C 1 185 ? 122.700 136.566 91.800  1.00 24.83  ? 185 HIS C O   1 
ATOM   8959  C CB  . HIS C 1 185 ? 119.806 137.514 92.303  1.00 24.83  ? 185 HIS C CB  1 
ATOM   8960  C CG  . HIS C 1 185 ? 119.088 136.313 91.770  1.00 24.83  ? 185 HIS C CG  1 
ATOM   8961  N ND1 . HIS C 1 185 ? 119.002 136.033 90.424  1.00 24.83  ? 185 HIS C ND1 1 
ATOM   8962  C CD2 . HIS C 1 185 ? 118.434 135.311 92.404  1.00 24.83  ? 185 HIS C CD2 1 
ATOM   8963  C CE1 . HIS C 1 185 ? 118.322 134.915 90.251  1.00 24.83  ? 185 HIS C CE1 1 
ATOM   8964  N NE2 . HIS C 1 185 ? 117.969 134.455 91.437  1.00 24.83  ? 185 HIS C NE2 1 
ATOM   8965  N N   . HIS C 1 186 ? 121.805 134.922 93.067  1.00 25.76  ? 186 HIS C N   1 
ATOM   8966  C CA  . HIS C 1 186 ? 122.603 133.827 92.528  1.00 25.76  ? 186 HIS C CA  1 
ATOM   8967  C C   . HIS C 1 186 ? 121.717 132.924 91.680  1.00 25.76  ? 186 HIS C C   1 
ATOM   8968  O O   . HIS C 1 186 ? 120.871 132.197 92.232  1.00 25.76  ? 186 HIS C O   1 
ATOM   8969  C CB  . HIS C 1 186 ? 123.251 133.025 93.658  1.00 25.76  ? 186 HIS C CB  1 
ATOM   8970  C CG  . HIS C 1 186 ? 124.062 133.854 94.605  1.00 25.76  ? 186 HIS C CG  1 
ATOM   8971  N ND1 . HIS C 1 186 ? 125.277 134.403 94.260  1.00 25.76  ? 186 HIS C ND1 1 
ATOM   8972  C CD2 . HIS C 1 186 ? 123.833 134.225 95.886  1.00 25.76  ? 186 HIS C CD2 1 
ATOM   8973  C CE1 . HIS C 1 186 ? 125.762 135.077 95.287  1.00 25.76  ? 186 HIS C CE1 1 
ATOM   8974  N NE2 . HIS C 1 186 ? 124.905 134.984 96.287  1.00 25.76  ? 186 HIS C NE2 1 
ATOM   8975  N N   . PRO C 1 187 ? 121.861 132.944 90.357  1.00 27.44  ? 187 PRO C N   1 
ATOM   8976  C CA  . PRO C 1 187 ? 121.042 132.090 89.490  1.00 27.44  ? 187 PRO C CA  1 
ATOM   8977  C C   . PRO C 1 187 ? 121.552 130.653 89.470  1.00 27.44  ? 187 PRO C C   1 
ATOM   8978  O O   . PRO C 1 187 ? 122.629 130.333 89.969  1.00 27.44  ? 187 PRO C O   1 
ATOM   8979  C CB  . PRO C 1 187 ? 121.186 132.741 88.106  1.00 27.44  ? 187 PRO C CB  1 
ATOM   8980  C CG  . PRO C 1 187 ? 121.871 134.057 88.343  1.00 27.44  ? 187 PRO C CG  1 
ATOM   8981  C CD  . PRO C 1 187 ? 122.680 133.881 89.577  1.00 27.44  ? 187 PRO C CD  1 
ATOM   8982  N N   . SER C 1 188 ? 120.746 129.781 88.867  1.00 30.71  ? 188 SER C N   1 
ATOM   8983  C CA  . SER C 1 188 ? 121.066 128.359 88.848  1.00 30.71  ? 188 SER C CA  1 
ATOM   8984  C C   . SER C 1 188 ? 121.836 127.924 87.607  1.00 30.71  ? 188 SER C C   1 
ATOM   8985  O O   . SER C 1 188 ? 122.586 126.945 87.675  1.00 30.71  ? 188 SER C O   1 
ATOM   8986  C CB  . SER C 1 188 ? 119.786 127.528 88.975  1.00 30.71  ? 188 SER C CB  1 
ATOM   8987  O OG  . SER C 1 188 ? 118.873 127.829 87.938  1.00 30.71  ? 188 SER C OG  1 
ATOM   8988  N N   . THR C 1 189 ? 121.680 128.613 86.475  1.00 33.26  ? 189 THR C N   1 
ATOM   8989  C CA  . THR C 1 189 ? 122.374 128.243 85.246  1.00 33.26  ? 189 THR C CA  1 
ATOM   8990  C C   . THR C 1 189 ? 122.919 129.488 84.558  1.00 33.26  ? 189 THR C C   1 
ATOM   8991  O O   . THR C 1 189 ? 122.550 130.619 84.879  1.00 33.26  ? 189 THR C O   1 
ATOM   8992  C CB  . THR C 1 189 ? 121.463 127.477 84.271  1.00 33.26  ? 189 THR C CB  1 
ATOM   8993  O OG1 . THR C 1 189 ? 120.440 128.350 83.776  1.00 33.26  ? 189 THR C OG1 1 
ATOM   8994  C CG2 . THR C 1 189 ? 120.825 126.267 84.939  1.00 33.26  ? 189 THR C CG2 1 
ATOM   8995  N N   . ASN C 1 190 ? 123.817 129.258 83.594  1.00 36.47  ? 190 ASN C N   1 
ATOM   8996  C CA  . ASN C 1 190 ? 124.336 130.348 82.772  1.00 36.47  ? 190 ASN C CA  1 
ATOM   8997  C C   . ASN C 1 190 ? 123.250 130.928 81.875  1.00 36.47  ? 190 ASN C C   1 
ATOM   8998  O O   . ASN C 1 190 ? 123.206 132.145 81.641  1.00 36.47  ? 190 ASN C O   1 
ATOM   8999  C CB  . ASN C 1 190 ? 125.511 129.852 81.928  1.00 36.47  ? 190 ASN C CB  1 
ATOM   9000  C CG  . ASN C 1 190 ? 126.836 129.964 82.647  1.00 36.47  ? 190 ASN C CG  1 
ATOM   9001  O OD1 . ASN C 1 190 ? 126.885 130.069 83.870  1.00 36.47  ? 190 ASN C OD1 1 
ATOM   9002  N ND2 . ASN C 1 190 ? 127.923 129.935 81.888  1.00 36.47  ? 190 ASN C ND2 1 
ATOM   9003  N N   . GLN C 1 191 ? 122.370 130.068 81.356  1.00 36.97  ? 191 GLN C N   1 
ATOM   9004  C CA  . GLN C 1 191 ? 121.281 130.539 80.509  1.00 36.97  ? 191 GLN C CA  1 
ATOM   9005  C C   . GLN C 1 191 ? 120.340 131.454 81.280  1.00 36.97  ? 191 GLN C C   1 
ATOM   9006  O O   . GLN C 1 191 ? 119.906 132.487 80.759  1.00 36.97  ? 191 GLN C O   1 
ATOM   9007  C CB  . GLN C 1 191 ? 120.519 129.350 79.927  1.00 36.97  ? 191 GLN C CB  1 
ATOM   9008  C CG  . GLN C 1 191 ? 119.371 129.744 79.016  1.00 36.97  ? 191 GLN C CG  1 
ATOM   9009  C CD  . GLN C 1 191 ? 119.839 130.133 77.629  1.00 36.97  ? 191 GLN C CD  1 
ATOM   9010  O OE1 . GLN C 1 191 ? 120.183 131.288 77.379  1.00 36.97  ? 191 GLN C OE1 1 
ATOM   9011  N NE2 . GLN C 1 191 ? 119.850 129.170 76.717  1.00 36.97  ? 191 GLN C NE2 1 
ATOM   9012  N N   . GLU C 1 192 ? 120.015 131.094 82.523  1.00 35.34  ? 192 GLU C N   1 
ATOM   9013  C CA  . GLU C 1 192 ? 119.192 131.965 83.356  1.00 35.34  ? 192 GLU C CA  1 
ATOM   9014  C C   . GLU C 1 192 ? 119.887 133.295 83.609  1.00 35.34  ? 192 GLU C C   1 
ATOM   9015  O O   . GLU C 1 192 ? 119.247 134.355 83.585  1.00 35.34  ? 192 GLU C O   1 
ATOM   9016  C CB  . GLU C 1 192 ? 118.868 131.273 84.680  1.00 35.34  ? 192 GLU C CB  1 
ATOM   9017  C CG  . GLU C 1 192 ? 117.727 131.908 85.451  1.00 35.34  ? 192 GLU C CG  1 
ATOM   9018  C CD  . GLU C 1 192 ? 117.300 131.081 86.647  1.00 35.34  ? 192 GLU C CD  1 
ATOM   9019  O OE1 . GLU C 1 192 ? 118.128 130.875 87.557  1.00 35.34  ? 192 GLU C OE1 1 
ATOM   9020  O OE2 . GLU C 1 192 ? 116.134 130.635 86.676  1.00 35.34  ? 192 GLU C OE2 1 
ATOM   9021  N N   . GLN C 1 193 ? 121.198 133.255 83.859  1.00 31.73  ? 193 GLN C N   1 
ATOM   9022  C CA  . GLN C 1 193 ? 121.962 134.480 84.060  1.00 31.73  ? 193 GLN C CA  1 
ATOM   9023  C C   . GLN C 1 193 ? 121.838 135.408 82.860  1.00 31.73  ? 193 GLN C C   1 
ATOM   9024  O O   . GLN C 1 193 ? 121.530 136.592 83.015  1.00 31.73  ? 193 GLN C O   1 
ATOM   9025  C CB  . GLN C 1 193 ? 123.428 134.148 84.333  1.00 31.73  ? 193 GLN C CB  1 
ATOM   9026  C CG  . GLN C 1 193 ? 124.379 135.319 84.150  1.00 31.73  ? 193 GLN C CG  1 
ATOM   9027  C CD  . GLN C 1 193 ? 124.342 136.306 85.303  1.00 31.73  ? 193 GLN C CD  1 
ATOM   9028  O OE1 . GLN C 1 193 ? 124.105 135.933 86.450  1.00 31.73  ? 193 GLN C OE1 1 
ATOM   9029  N NE2 . GLN C 1 193 ? 124.582 137.574 85.000  1.00 31.73  ? 193 GLN C NE2 1 
ATOM   9030  N N   . THR C 1 194 ? 122.057 134.884 81.649  1.00 34.69  ? 194 THR C N   1 
ATOM   9031  C CA  . THR C 1 194 ? 121.942 135.742 80.470  1.00 34.69  ? 194 THR C CA  1 
ATOM   9032  C C   . THR C 1 194 ? 120.499 136.158 80.208  1.00 34.69  ? 194 THR C C   1 
ATOM   9033  O O   . THR C 1 194 ? 120.262 137.230 79.642  1.00 34.69  ? 194 THR C O   1 
ATOM   9034  C CB  . THR C 1 194 ? 122.522 135.055 79.231  1.00 34.69  ? 194 THR C CB  1 
ATOM   9035  O OG1 . THR C 1 194 ? 121.954 133.748 79.084  1.00 34.69  ? 194 THR C OG1 1 
ATOM   9036  C CG2 . THR C 1 194 ? 124.030 134.946 79.338  1.00 34.69  ? 194 THR C CG2 1 
ATOM   9037  N N   . ASN C 1 195 ? 119.527 135.339 80.613  1.00 35.77  ? 195 ASN C N   1 
ATOM   9038  C CA  . ASN C 1 195 ? 118.128 135.675 80.370  1.00 35.77  ? 195 ASN C CA  1 
ATOM   9039  C C   . ASN C 1 195 ? 117.662 136.826 81.254  1.00 35.77  ? 195 ASN C C   1 
ATOM   9040  O O   . ASN C 1 195 ? 116.917 137.700 80.798  1.00 35.77  ? 195 ASN C O   1 
ATOM   9041  C CB  . ASN C 1 195 ? 117.249 134.445 80.591  1.00 35.77  ? 195 ASN C CB  1 
ATOM   9042  C CG  . ASN C 1 195 ? 117.296 133.477 79.426  1.00 35.77  ? 195 ASN C CG  1 
ATOM   9043  O OD1 . ASN C 1 195 ? 117.812 133.797 78.356  1.00 35.77  ? 195 ASN C OD1 1 
ATOM   9044  N ND2 . ASN C 1 195 ? 116.758 132.282 79.632  1.00 35.77  ? 195 ASN C ND2 1 
ATOM   9045  N N   . LEU C 1 196 ? 118.076 136.840 82.523  1.00 31.77  ? 196 LEU C N   1 
ATOM   9046  C CA  . LEU C 1 196 ? 117.619 137.892 83.428  1.00 31.77  ? 196 LEU C CA  1 
ATOM   9047  C C   . LEU C 1 196 ? 118.467 139.152 83.298  1.00 31.77  ? 196 LEU C C   1 
ATOM   9048  O O   . LEU C 1 196 ? 117.936 140.264 83.249  1.00 31.77  ? 196 LEU C O   1 
ATOM   9049  C CB  . LEU C 1 196 ? 117.633 137.394 84.874  1.00 31.77  ? 196 LEU C CB  1 
ATOM   9050  C CG  . LEU C 1 196 ? 116.829 136.138 85.215  1.00 31.77  ? 196 LEU C CG  1 
ATOM   9051  C CD1 . LEU C 1 196 ? 116.693 136.000 86.720  1.00 31.77  ? 196 LEU C CD1 1 
ATOM   9052  C CD2 . LEU C 1 196 ? 115.464 136.165 84.553  1.00 31.77  ? 196 LEU C CD2 1 
ATOM   9053  N N   . TYR C 1 197 ? 119.785 138.993 83.256  1.00 30.29  ? 197 TYR C N   1 
ATOM   9054  C CA  . TYR C 1 197 ? 120.725 140.101 83.148  1.00 30.29  ? 197 TYR C CA  1 
ATOM   9055  C C   . TYR C 1 197 ? 121.608 139.841 81.938  1.00 30.29  ? 197 TYR C C   1 
ATOM   9056  O O   . TYR C 1 197 ? 122.216 138.773 81.831  1.00 30.29  ? 197 TYR C O   1 
ATOM   9057  C CB  . TYR C 1 197 ? 121.552 140.232 84.428  1.00 30.29  ? 197 TYR C CB  1 
ATOM   9058  C CG  . TYR C 1 197 ? 120.797 139.795 85.666  1.00 30.29  ? 197 TYR C CG  1 
ATOM   9059  C CD1 . TYR C 1 197 ? 119.850 140.624 86.254  1.00 30.29  ? 197 TYR C CD1 1 
ATOM   9060  C CD2 . TYR C 1 197 ? 121.019 138.549 86.235  1.00 30.29  ? 197 TYR C CD2 1 
ATOM   9061  C CE1 . TYR C 1 197 ? 119.153 140.227 87.376  1.00 30.29  ? 197 TYR C CE1 1 
ATOM   9062  C CE2 . TYR C 1 197 ? 120.327 138.143 87.359  1.00 30.29  ? 197 TYR C CE2 1 
ATOM   9063  C CZ  . TYR C 1 197 ? 119.396 138.987 87.925  1.00 30.29  ? 197 TYR C CZ  1 
ATOM   9064  O OH  . TYR C 1 197 ? 118.706 138.587 89.042  1.00 30.29  ? 197 TYR C OH  1 
ATOM   9065  N N   . VAL C 1 198 ? 121.683 140.813 81.032  1.00 31.39  ? 198 VAL C N   1 
ATOM   9066  C CA  . VAL C 1 198 ? 122.247 140.550 79.709  1.00 31.39  ? 198 VAL C CA  1 
ATOM   9067  C C   . VAL C 1 198 ? 123.698 140.094 79.811  1.00 31.39  ? 198 VAL C C   1 
ATOM   9068  O O   . VAL C 1 198 ? 124.135 139.205 79.072  1.00 31.39  ? 198 VAL C O   1 
ATOM   9069  C CB  . VAL C 1 198 ? 122.097 141.796 78.818  1.00 31.39  ? 198 VAL C CB  1 
ATOM   9070  C CG1 . VAL C 1 198 ? 122.759 141.575 77.472  1.00 31.39  ? 198 VAL C CG1 1 
ATOM   9071  C CG2 . VAL C 1 198 ? 120.626 142.131 78.647  1.00 31.39  ? 198 VAL C CG2 1 
ATOM   9072  N N   . GLN C 1 199 ? 124.460 140.678 80.728  1.00 31.74  ? 199 GLN C N   1 
ATOM   9073  C CA  . GLN C 1 199 ? 125.871 140.346 80.851  1.00 31.74  ? 199 GLN C CA  1 
ATOM   9074  C C   . GLN C 1 199 ? 126.056 138.939 81.410  1.00 31.74  ? 199 GLN C C   1 
ATOM   9075  O O   . GLN C 1 199 ? 125.285 138.471 82.251  1.00 31.74  ? 199 GLN C O   1 
ATOM   9076  C CB  . GLN C 1 199 ? 126.580 141.366 81.741  1.00 31.74  ? 199 GLN C CB  1 
ATOM   9077  C CG  . GLN C 1 199 ? 126.834 142.706 81.065  1.00 31.74  ? 199 GLN C CG  1 
ATOM   9078  C CD  . GLN C 1 199 ? 125.565 143.503 80.835  1.00 31.74  ? 199 GLN C CD  1 
ATOM   9079  O OE1 . GLN C 1 199 ? 124.893 143.909 81.779  1.00 31.74  ? 199 GLN C OE1 1 
ATOM   9080  N NE2 . GLN C 1 199 ? 125.225 143.716 79.573  1.00 31.74  ? 199 GLN C NE2 1 
ATOM   9081  N N   . ALA C 1 200 ? 127.101 138.263 80.930  1.00 34.16  ? 200 ALA C N   1 
ATOM   9082  C CA  . ALA C 1 200 ? 127.375 136.890 81.337  1.00 34.16  ? 200 ALA C CA  1 
ATOM   9083  C C   . ALA C 1 200 ? 127.935 136.788 82.748  1.00 34.16  ? 200 ALA C C   1 
ATOM   9084  O O   . ALA C 1 200 ? 127.971 135.685 83.300  1.00 34.16  ? 200 ALA C O   1 
ATOM   9085  C CB  . ALA C 1 200 ? 128.343 136.233 80.353  1.00 34.16  ? 200 ALA C CB  1 
ATOM   9086  N N   . SER C 1 201 ? 128.371 137.897 83.340  1.00 34.61  ? 201 SER C N   1 
ATOM   9087  C CA  . SER C 1 201 ? 128.881 137.887 84.707  1.00 34.61  ? 201 SER C CA  1 
ATOM   9088  C C   . SER C 1 201 ? 128.535 139.222 85.350  1.00 34.61  ? 201 SER C C   1 
ATOM   9089  O O   . SER C 1 201 ? 129.065 140.260 84.946  1.00 34.61  ? 201 SER C O   1 
ATOM   9090  C CB  . SER C 1 201 ? 130.385 137.638 84.731  1.00 34.61  ? 201 SER C CB  1 
ATOM   9091  O OG  . SER C 1 201 ? 130.909 137.825 86.032  1.00 34.61  ? 201 SER C OG  1 
ATOM   9092  N N   . GLY C 1 202 ? 127.652 139.194 86.345  1.00 31.29  ? 202 GLY C N   1 
ATOM   9093  C CA  . GLY C 1 202 ? 127.244 140.398 87.034  1.00 31.29  ? 202 GLY C CA  1 
ATOM   9094  C C   . GLY C 1 202 ? 128.235 140.830 88.096  1.00 31.29  ? 202 GLY C C   1 
ATOM   9095  O O   . GLY C 1 202 ? 129.217 140.155 88.398  1.00 31.29  ? 202 GLY C O   1 
ATOM   9096  N N   . ARG C 1 203 ? 127.953 141.992 88.680  1.00 29.37  ? 203 ARG C N   1 
ATOM   9097  C CA  . ARG C 1 203 ? 128.820 142.579 89.691  1.00 29.37  ? 203 ARG C CA  1 
ATOM   9098  C C   . ARG C 1 203 ? 128.059 143.680 90.413  1.00 29.37  ? 203 ARG C C   1 
ATOM   9099  O O   . ARG C 1 203 ? 127.371 144.485 89.769  1.00 29.37  ? 203 ARG C O   1 
ATOM   9100  C CB  . ARG C 1 203 ? 130.100 143.144 89.060  1.00 29.37  ? 203 ARG C CB  1 
ATOM   9101  C CG  . ARG C 1 203 ? 131.017 143.843 90.034  1.00 29.37  ? 203 ARG C CG  1 
ATOM   9102  C CD  . ARG C 1 203 ? 132.137 144.582 89.314  1.00 29.37  ? 203 ARG C CD  1 
ATOM   9103  N NE  . ARG C 1 203 ? 131.651 145.419 88.223  1.00 29.37  ? 203 ARG C NE  1 
ATOM   9104  C CZ  . ARG C 1 203 ? 131.041 146.586 88.381  1.00 29.37  ? 203 ARG C CZ  1 
ATOM   9105  N NH1 . ARG C 1 203 ? 130.806 147.089 89.581  1.00 29.37  ? 203 ARG C NH1 1 
ATOM   9106  N NH2 . ARG C 1 203 ? 130.656 147.267 87.306  1.00 29.37  ? 203 ARG C NH2 1 
ATOM   9107  N N   . VAL C 1 204 ? 128.194 143.712 91.743  1.00 27.04  ? 204 VAL C N   1 
ATOM   9108  C CA  . VAL C 1 204 ? 127.548 144.717 92.584  1.00 27.04  ? 204 VAL C CA  1 
ATOM   9109  C C   . VAL C 1 204 ? 128.596 145.350 93.491  1.00 27.04  ? 204 VAL C C   1 
ATOM   9110  O O   . VAL C 1 204 ? 129.305 144.641 94.209  1.00 27.04  ? 204 VAL C O   1 
ATOM   9111  C CB  . VAL C 1 204 ? 126.407 144.109 93.425  1.00 27.04  ? 204 VAL C CB  1 
ATOM   9112  C CG1 . VAL C 1 204 ? 125.800 145.156 94.345  1.00 27.04  ? 204 VAL C CG1 1 
ATOM   9113  C CG2 . VAL C 1 204 ? 125.344 143.500 92.529  1.00 27.04  ? 204 VAL C CG2 1 
ATOM   9114  N N   . THR C 1 205 ? 128.679 146.682 93.483  1.00 27.57  ? 205 THR C N   1 
ATOM   9115  C CA  . THR C 1 205 ? 129.612 147.424 94.322  1.00 27.57  ? 205 THR C CA  1 
ATOM   9116  C C   . THR C 1 205 ? 128.851 148.490 95.095  1.00 27.57  ? 205 THR C C   1 
ATOM   9117  O O   . THR C 1 205 ? 128.101 149.274 94.505  1.00 27.57  ? 205 THR C O   1 
ATOM   9118  C CB  . THR C 1 205 ? 130.721 148.079 93.483  1.00 27.57  ? 205 THR C CB  1 
ATOM   9119  O OG1 . THR C 1 205 ? 131.371 147.088 92.679  1.00 27.57  ? 205 THR C OG1 1 
ATOM   9120  C CG2 . THR C 1 205 ? 131.750 148.750 94.379  1.00 27.57  ? 205 THR C CG2 1 
ATOM   9121  N N   . VAL C 1 206 ? 129.044 148.518 96.411  1.00 25.91  ? 206 VAL C N   1 
ATOM   9122  C CA  . VAL C 1 206 ? 128.374 149.462 97.299  1.00 25.91  ? 206 VAL C CA  1 
ATOM   9123  C C   . VAL C 1 206 ? 129.436 150.119 98.168  1.00 25.91  ? 206 VAL C C   1 
ATOM   9124  O O   . VAL C 1 206 ? 130.198 149.422 98.847  1.00 25.91  ? 206 VAL C O   1 
ATOM   9125  C CB  . VAL C 1 206 ? 127.310 148.766 98.173  1.00 25.91  ? 206 VAL C CB  1 
ATOM   9126  C CG1 . VAL C 1 206 ? 126.650 149.760 99.110  1.00 25.91  ? 206 VAL C CG1 1 
ATOM   9127  C CG2 . VAL C 1 206 ? 126.269 148.074 97.305  1.00 25.91  ? 206 VAL C CG2 1 
ATOM   9128  N N   . SER C 1 207 ? 129.488 151.450 98.159  1.00 28.81  ? 207 SER C N   1 
ATOM   9129  C CA  . SER C 1 207 ? 130.601 152.113 98.826  1.00 28.81  ? 207 SER C CA  1 
ATOM   9130  C C   . SER C 1 207 ? 130.177 153.436 99.450  1.00 28.81  ? 207 SER C C   1 
ATOM   9131  O O   . SER C 1 207 ? 129.208 154.072 99.030  1.00 28.81  ? 207 SER C O   1 
ATOM   9132  C CB  . SER C 1 207 ? 131.765 152.342 97.856  1.00 28.81  ? 207 SER C CB  1 
ATOM   9133  O OG  . SER C 1 207 ? 131.333 153.041 96.706  1.00 28.81  ? 207 SER C OG  1 
ATOM   9134  N N   . THR C 1 208 ? 130.922 153.825 100.480 1.00 31.63  ? 208 THR C N   1 
ATOM   9135  C CA  . THR C 1 208 ? 130.913 155.156 101.073 1.00 31.63  ? 208 THR C CA  1 
ATOM   9136  C C   . THR C 1 208 ? 132.320 155.744 100.956 1.00 31.63  ? 208 THR C C   1 
ATOM   9137  O O   . THR C 1 208 ? 133.198 155.179 100.300 1.00 31.63  ? 208 THR C O   1 
ATOM   9138  C CB  . THR C 1 208 ? 130.447 155.117 102.532 1.00 31.63  ? 208 THR C CB  1 
ATOM   9139  O OG1 . THR C 1 208 ? 131.442 154.479 103.339 1.00 31.63  ? 208 THR C OG1 1 
ATOM   9140  C CG2 . THR C 1 208 ? 129.129 154.368 102.667 1.00 31.63  ? 208 THR C CG2 1 
ATOM   9141  N N   . ARG C 1 209 ? 132.536 156.891 101.600 1.00 33.63  ? 209 ARG C N   1 
ATOM   9142  C CA  . ARG C 1 209 ? 133.868 157.486 101.601 1.00 33.63  ? 209 ARG C CA  1 
ATOM   9143  C C   . ARG C 1 209 ? 134.856 156.703 102.455 1.00 33.63  ? 209 ARG C C   1 
ATOM   9144  O O   . ARG C 1 209 ? 136.067 156.860 102.275 1.00 33.63  ? 209 ARG C O   1 
ATOM   9145  C CB  . ARG C 1 209 ? 133.805 158.936 102.083 1.00 33.63  ? 209 ARG C CB  1 
ATOM   9146  C CG  . ARG C 1 209 ? 133.068 159.870 101.143 1.00 33.63  ? 209 ARG C CG  1 
ATOM   9147  C CD  . ARG C 1 209 ? 133.667 161.262 101.160 1.00 33.63  ? 209 ARG C CD  1 
ATOM   9148  N NE  . ARG C 1 209 ? 132.835 162.222 100.444 1.00 33.63  ? 209 ARG C NE  1 
ATOM   9149  C CZ  . ARG C 1 209 ? 131.829 162.893 100.986 1.00 33.63  ? 209 ARG C CZ  1 
ATOM   9150  N NH1 . ARG C 1 209 ? 131.514 162.753 102.263 1.00 33.63  ? 209 ARG C NH1 1 
ATOM   9151  N NH2 . ARG C 1 209 ? 131.123 163.726 100.228 1.00 33.63  ? 209 ARG C NH2 1 
ATOM   9152  N N   . ARG C 1 210 ? 134.378 155.857 103.367 1.00 36.36  ? 210 ARG C N   1 
ATOM   9153  C CA  . ARG C 1 210 ? 135.260 155.129 104.266 1.00 36.36  ? 210 ARG C CA  1 
ATOM   9154  C C   . ARG C 1 210 ? 135.166 153.612 104.154 1.00 36.36  ? 210 ARG C C   1 
ATOM   9155  O O   . ARG C 1 210 ? 135.837 152.916 104.923 1.00 36.36  ? 210 ARG C O   1 
ATOM   9156  C CB  . ARG C 1 210 ? 134.992 155.540 105.721 1.00 36.36  ? 210 ARG C CB  1 
ATOM   9157  C CG  . ARG C 1 210 ? 133.532 155.502 106.131 1.00 36.36  ? 210 ARG C CG  1 
ATOM   9158  C CD  . ARG C 1 210 ? 133.244 156.522 107.221 1.00 36.36  ? 210 ARG C CD  1 
ATOM   9159  N NE  . ARG C 1 210 ? 133.023 157.856 106.678 1.00 36.36  ? 210 ARG C NE  1 
ATOM   9160  C CZ  . ARG C 1 210 ? 132.764 158.932 107.409 1.00 36.36  ? 210 ARG C CZ  1 
ATOM   9161  N NH1 . ARG C 1 210 ? 132.683 158.868 108.728 1.00 36.36  ? 210 ARG C NH1 1 
ATOM   9162  N NH2 . ARG C 1 210 ? 132.580 160.100 106.801 1.00 36.36  ? 210 ARG C NH2 1 
ATOM   9163  N N   . SER C 1 211 ? 134.372 153.075 103.231 1.00 33.42  ? 211 SER C N   1 
ATOM   9164  C CA  . SER C 1 211 ? 134.228 151.628 103.129 1.00 33.42  ? 211 SER C CA  1 
ATOM   9165  C C   . SER C 1 211 ? 133.731 151.260 101.739 1.00 33.42  ? 211 SER C C   1 
ATOM   9166  O O   . SER C 1 211 ? 133.214 152.102 101.002 1.00 33.42  ? 211 SER C O   1 
ATOM   9167  C CB  . SER C 1 211 ? 133.276 151.088 104.201 1.00 33.42  ? 211 SER C CB  1 
ATOM   9168  O OG  . SER C 1 211 ? 131.925 151.250 103.809 1.00 33.42  ? 211 SER C OG  1 
ATOM   9169  N N   . GLN C 1 212 ? 133.895 149.983 101.393 1.00 29.84  ? 212 GLN C N   1 
ATOM   9170  C CA  . GLN C 1 212 ? 133.453 149.467 100.105 1.00 29.84  ? 212 GLN C CA  1 
ATOM   9171  C C   . GLN C 1 212 ? 133.245 147.962 100.205 1.00 29.84  ? 212 GLN C C   1 
ATOM   9172  O O   . GLN C 1 212 ? 133.948 147.274 100.949 1.00 29.84  ? 212 GLN C O   1 
ATOM   9173  C CB  . GLN C 1 212 ? 134.459 149.786 98.996  1.00 29.84  ? 212 GLN C CB  1 
ATOM   9174  C CG  . GLN C 1 212 ? 135.908 149.598 99.404  1.00 29.84  ? 212 GLN C CG  1 
ATOM   9175  C CD  . GLN C 1 212 ? 136.619 148.559 98.564  1.00 29.84  ? 212 GLN C CD  1 
ATOM   9176  O OE1 . GLN C 1 212 ? 136.012 147.595 98.103  1.00 29.84  ? 212 GLN C OE1 1 
ATOM   9177  N NE2 . GLN C 1 212 ? 137.915 148.750 98.360  1.00 29.84  ? 212 GLN C NE2 1 
ATOM   9178  N N   . GLN C 1 213 ? 132.267 147.464 99.447  1.00 28.46  ? 213 GLN C N   1 
ATOM   9179  C CA  . GLN C 1 213 ? 131.992 146.035 99.331  1.00 28.46  ? 213 GLN C CA  1 
ATOM   9180  C C   . GLN C 1 213 ? 131.668 145.712 97.880  1.00 28.46  ? 213 GLN C C   1 
ATOM   9181  O O   . GLN C 1 213 ? 130.852 146.399 97.259  1.00 28.46  ? 213 GLN C O   1 
ATOM   9182  C CB  . GLN C 1 213 ? 130.823 145.606 100.231 1.00 28.46  ? 213 GLN C CB  1 
ATOM   9183  C CG  . GLN C 1 213 ? 131.037 145.829 101.717 1.00 28.46  ? 213 GLN C CG  1 
ATOM   9184  C CD  . GLN C 1 213 ? 129.738 145.827 102.507 1.00 28.46  ? 213 GLN C CD  1 
ATOM   9185  O OE1 . GLN C 1 213 ? 129.183 146.882 102.809 1.00 28.46  ? 213 GLN C OE1 1 
ATOM   9186  N NE2 . GLN C 1 213 ? 129.254 144.641 102.850 1.00 28.46  ? 213 GLN C NE2 1 
ATOM   9187  N N   . THR C 1 214 ? 132.294 144.666 97.343  1.00 29.24  ? 214 THR C N   1 
ATOM   9188  C CA  . THR C 1 214 ? 132.015 144.207 95.987  1.00 29.24  ? 214 THR C CA  1 
ATOM   9189  C C   . THR C 1 214 ? 131.683 142.723 96.013  1.00 29.24  ? 214 THR C C   1 
ATOM   9190  O O   . THR C 1 214 ? 132.395 141.935 96.640  1.00 29.24  ? 214 THR C O   1 
ATOM   9191  C CB  . THR C 1 214 ? 133.197 144.465 95.045  1.00 29.24  ? 214 THR C CB  1 
ATOM   9192  O OG1 . THR C 1 214 ? 133.390 145.876 94.889  1.00 29.24  ? 214 THR C OG1 1 
ATOM   9193  C CG2 . THR C 1 214 ? 132.934 143.851 93.676  1.00 29.24  ? 214 THR C CG2 1 
ATOM   9194  N N   . ILE C 1 215 ? 130.603 142.351 95.328  1.00 28.25  ? 215 ILE C N   1 
ATOM   9195  C CA  . ILE C 1 215 ? 130.109 140.982 95.290  1.00 28.25  ? 215 ILE C CA  1 
ATOM   9196  C C   . ILE C 1 215 ? 129.984 140.543 93.837  1.00 28.25  ? 215 ILE C C   1 
ATOM   9197  O O   . ILE C 1 215 ? 129.394 141.255 93.011  1.00 28.25  ? 215 ILE C O   1 
ATOM   9198  C CB  . ILE C 1 215 ? 128.755 140.838 96.014  1.00 28.25  ? 215 ILE C CB  1 
ATOM   9199  C CG1 . ILE C 1 215 ? 128.785 141.544 97.373  1.00 28.25  ? 215 ILE C CG1 1 
ATOM   9200  C CG2 . ILE C 1 215 ? 128.390 139.372 96.180  1.00 28.25  ? 215 ILE C CG2 1 
ATOM   9201  C CD1 . ILE C 1 215 ? 129.644 140.863 98.405  1.00 28.25  ? 215 ILE C CD1 1 
ATOM   9202  N N   . VAL C 1 216 ? 130.549 139.384 93.533  1.00 29.91  ? 216 VAL C N   1 
ATOM   9203  C CA  . VAL C 1 216 ? 130.373 138.696 92.256  1.00 29.91  ? 216 VAL C CA  1 
ATOM   9204  C C   . VAL C 1 216 ? 129.464 137.497 92.496  1.00 29.91  ? 216 VAL C C   1 
ATOM   9205  O O   . VAL C 1 216 ? 129.747 136.692 93.389  1.00 29.91  ? 216 VAL C O   1 
ATOM   9206  C CB  . VAL C 1 216 ? 131.719 138.244 91.654  1.00 29.91  ? 216 VAL C CB  1 
ATOM   9207  C CG1 . VAL C 1 216 ? 131.495 137.437 90.384  1.00 29.91  ? 216 VAL C CG1 1 
ATOM   9208  C CG2 . VAL C 1 216 ? 132.604 139.442 91.371  1.00 29.91  ? 216 VAL C CG2 1 
ATOM   9209  N N   . PRO C 1 217 ? 128.374 137.349 91.749  1.00 28.81  ? 217 PRO C N   1 
ATOM   9210  C CA  . PRO C 1 217 ? 127.429 136.259 92.020  1.00 28.81  ? 217 PRO C CA  1 
ATOM   9211  C C   . PRO C 1 217 ? 127.989 134.889 91.660  1.00 28.81  ? 217 PRO C C   1 
ATOM   9212  O O   . PRO C 1 217 ? 128.905 134.746 90.848  1.00 28.81  ? 217 PRO C O   1 
ATOM   9213  C CB  . PRO C 1 217 ? 126.222 136.609 91.144  1.00 28.81  ? 217 PRO C CB  1 
ATOM   9214  C CG  . PRO C 1 217 ? 126.754 137.517 90.099  1.00 28.81  ? 217 PRO C CG  1 
ATOM   9215  C CD  . PRO C 1 217 ? 127.886 138.268 90.710  1.00 28.81  ? 217 PRO C CD  1 
ATOM   9216  N N   . ASN C 1 218 ? 127.408 133.869 92.288  1.00 30.67  ? 218 ASN C N   1 
ATOM   9217  C CA  . ASN C 1 218 ? 127.760 132.474 92.063  1.00 30.67  ? 218 ASN C CA  1 
ATOM   9218  C C   . ASN C 1 218 ? 126.641 131.766 91.308  1.00 30.67  ? 218 ASN C C   1 
ATOM   9219  O O   . ASN C 1 218 ? 125.459 131.997 91.574  1.00 30.67  ? 218 ASN C O   1 
ATOM   9220  C CB  . ASN C 1 218 ? 128.018 131.750 93.387  1.00 30.67  ? 218 ASN C CB  1 
ATOM   9221  C CG  . ASN C 1 218 ? 128.798 132.594 94.376  1.00 30.67  ? 218 ASN C CG  1 
ATOM   9222  O OD1 . ASN C 1 218 ? 129.794 133.227 94.026  1.00 30.67  ? 218 ASN C OD1 1 
ATOM   9223  N ND2 . ASN C 1 218 ? 128.350 132.600 95.625  1.00 30.67  ? 218 ASN C ND2 1 
ATOM   9224  N N   . ILE C 1 219 ? 127.017 130.900 90.371  1.00 30.22  ? 219 ILE C N   1 
ATOM   9225  C CA  . ILE C 1 219 ? 126.070 130.190 89.519  1.00 30.22  ? 219 ILE C CA  1 
ATOM   9226  C C   . ILE C 1 219 ? 126.169 128.698 89.811  1.00 30.22  ? 219 ILE C C   1 
ATOM   9227  O O   . ILE C 1 219 ? 127.270 128.167 89.988  1.00 30.22  ? 219 ILE C O   1 
ATOM   9228  C CB  . ILE C 1 219 ? 126.336 130.488 88.027  1.00 30.22  ? 219 ILE C CB  1 
ATOM   9229  C CG1 . ILE C 1 219 ? 125.907 131.917 87.691  1.00 30.22  ? 219 ILE C CG1 1 
ATOM   9230  C CG2 . ILE C 1 219 ? 125.604 129.504 87.130  1.00 30.22  ? 219 ILE C CG2 1 
ATOM   9231  C CD1 . ILE C 1 219 ? 126.613 132.505 86.497  1.00 30.22  ? 219 ILE C CD1 1 
ATOM   9232  N N   . GLY C 1 220 ? 125.026 128.032 89.888  1.00 28.86  ? 220 GLY C N   1 
ATOM   9233  C CA  . GLY C 1 220 ? 124.998 126.599 90.099  1.00 28.86  ? 220 GLY C CA  1 
ATOM   9234  C C   . GLY C 1 220 ? 123.658 126.132 90.617  1.00 28.86  ? 220 GLY C C   1 
ATOM   9235  O O   . GLY C 1 220 ? 122.902 126.875 91.240  1.00 28.86  ? 220 GLY C O   1 
ATOM   9236  N N   . SER C 1 221 ? 123.365 124.860 90.348  1.00 28.76  ? 221 SER C N   1 
ATOM   9237  C CA  . SER C 1 221 ? 122.112 124.265 90.797  1.00 28.76  ? 221 SER C CA  1 
ATOM   9238  C C   . SER C 1 221 ? 122.149 123.972 92.292  1.00 28.76  ? 221 SER C C   1 
ATOM   9239  O O   . SER C 1 221 ? 123.172 123.552 92.836  1.00 28.76  ? 221 SER C O   1 
ATOM   9240  C CB  . SER C 1 221 ? 121.820 122.980 90.025  1.00 28.76  ? 221 SER C CB  1 
ATOM   9241  O OG  . SER C 1 221 ? 121.550 123.248 88.663  1.00 28.76  ? 221 SER C OG  1 
ATOM   9242  N N   . ARG C 1 222 ? 121.017 124.184 92.947  1.00 27.82  ? 222 ARG C N   1 
ATOM   9243  C CA  . ARG C 1 222 ? 120.831 123.988 94.375  1.00 27.82  ? 222 ARG C CA  1 
ATOM   9244  C C   . ARG C 1 222 ? 119.523 123.250 94.608  1.00 27.82  ? 222 ARG C C   1 
ATOM   9245  O O   . ARG C 1 222 ? 118.667 123.201 93.718  1.00 27.82  ? 222 ARG C O   1 
ATOM   9246  C CB  . ARG C 1 222 ? 120.823 125.333 95.116  1.00 27.82  ? 222 ARG C CB  1 
ATOM   9247  C CG  . ARG C 1 222 ? 122.177 126.004 95.186  1.00 27.82  ? 222 ARG C CG  1 
ATOM   9248  C CD  . ARG C 1 222 ? 122.049 127.505 95.140  1.00 27.82  ? 222 ARG C CD  1 
ATOM   9249  N NE  . ARG C 1 222 ? 123.277 128.159 94.712  1.00 27.82  ? 222 ARG C NE  1 
ATOM   9250  C CZ  . ARG C 1 222 ? 123.351 129.017 93.704  1.00 27.82  ? 222 ARG C CZ  1 
ATOM   9251  N NH1 . ARG C 1 222 ? 122.288 129.325 92.981  1.00 27.82  ? 222 ARG C NH1 1 
ATOM   9252  N NH2 . ARG C 1 222 ? 124.521 129.574 93.412  1.00 27.82  ? 222 ARG C NH2 1 
ATOM   9253  N N   . PRO C 1 223 ? 119.344 122.640 95.783  1.00 28.74  ? 223 PRO C N   1 
ATOM   9254  C CA  . PRO C 1 223 ? 118.076 121.951 96.061  1.00 28.74  ? 223 PRO C CA  1 
ATOM   9255  C C   . PRO C 1 223 ? 116.892 122.906 96.005  1.00 28.74  ? 223 PRO C C   1 
ATOM   9256  O O   . PRO C 1 223 ? 116.985 124.066 96.409  1.00 28.74  ? 223 PRO C O   1 
ATOM   9257  C CB  . PRO C 1 223 ? 118.275 121.388 97.474  1.00 28.74  ? 223 PRO C CB  1 
ATOM   9258  C CG  . PRO C 1 223 ? 119.735 121.375 97.691  1.00 28.74  ? 223 PRO C CG  1 
ATOM   9259  C CD  . PRO C 1 223 ? 120.301 122.496 96.893  1.00 28.74  ? 223 PRO C CD  1 
ATOM   9260  N N   . TRP C 1 224 ? 115.772 122.400 95.494  1.00 30.66  ? 224 TRP C N   1 
ATOM   9261  C CA  . TRP C 1 224 ? 114.559 123.199 95.386  1.00 30.66  ? 224 TRP C CA  1 
ATOM   9262  C C   . TRP C 1 224 ? 114.054 123.610 96.762  1.00 30.66  ? 224 TRP C C   1 
ATOM   9263  O O   . TRP C 1 224 ? 113.900 122.774 97.656  1.00 30.66  ? 224 TRP C O   1 
ATOM   9264  C CB  . TRP C 1 224 ? 113.475 122.410 94.655  1.00 30.66  ? 224 TRP C CB  1 
ATOM   9265  C CG  . TRP C 1 224 ? 113.467 122.587 93.175  1.00 30.66  ? 224 TRP C CG  1 
ATOM   9266  C CD1 . TRP C 1 224 ? 114.532 122.876 92.376  1.00 30.66  ? 224 TRP C CD1 1 
ATOM   9267  C CD2 . TRP C 1 224 ? 112.335 122.473 92.309  1.00 30.66  ? 224 TRP C CD2 1 
ATOM   9268  N NE1 . TRP C 1 224 ? 114.132 122.955 91.066  1.00 30.66  ? 224 TRP C NE1 1 
ATOM   9269  C CE2 . TRP C 1 224 ? 112.786 122.712 90.999  1.00 30.66  ? 224 TRP C CE2 1 
ATOM   9270  C CE3 . TRP C 1 224 ? 110.981 122.197 92.516  1.00 30.66  ? 224 TRP C CE3 1 
ATOM   9271  C CZ2 . TRP C 1 224 ? 111.933 122.682 89.899  1.00 30.66  ? 224 TRP C CZ2 1 
ATOM   9272  C CZ3 . TRP C 1 224 ? 110.137 122.167 91.424  1.00 30.66  ? 224 TRP C CZ3 1 
ATOM   9273  C CH2 . TRP C 1 224 ? 110.616 122.407 90.132  1.00 30.66  ? 224 TRP C CH2 1 
ATOM   9274  N N   . VAL C 1 225 ? 113.798 124.903 96.931  1.00 27.72  ? 225 VAL C N   1 
ATOM   9275  C CA  . VAL C 1 225 ? 113.108 125.431 98.102  1.00 27.72  ? 225 VAL C CA  1 
ATOM   9276  C C   . VAL C 1 225 ? 111.929 126.238 97.584  1.00 27.72  ? 225 VAL C C   1 
ATOM   9277  O O   . VAL C 1 225 ? 112.119 127.279 96.944  1.00 27.72  ? 225 VAL C O   1 
ATOM   9278  C CB  . VAL C 1 225 ? 114.016 126.292 98.990  1.00 27.72  ? 225 VAL C CB  1 
ATOM   9279  C CG1 . VAL C 1 225 ? 113.232 126.833 100.171 1.00 27.72  ? 225 VAL C CG1 1 
ATOM   9280  C CG2 . VAL C 1 225 ? 115.206 125.488 99.471  1.00 27.72  ? 225 VAL C CG2 1 
ATOM   9281  N N   . ARG C 1 226 ? 110.715 125.760 97.858  1.00 27.88  ? 226 ARG C N   1 
ATOM   9282  C CA  . ARG C 1 226 ? 109.482 126.367 97.355  1.00 27.88  ? 226 ARG C CA  1 
ATOM   9283  C C   . ARG C 1 226 ? 109.533 126.555 95.840  1.00 27.88  ? 226 ARG C C   1 
ATOM   9284  O O   . ARG C 1 226 ? 109.081 127.566 95.300  1.00 27.88  ? 226 ARG C O   1 
ATOM   9285  C CB  . ARG C 1 226 ? 109.181 127.685 98.072  1.00 27.88  ? 226 ARG C CB  1 
ATOM   9286  C CG  . ARG C 1 226 ? 108.800 127.499 99.534  1.00 27.88  ? 226 ARG C CG  1 
ATOM   9287  C CD  . ARG C 1 226 ? 108.442 128.806 100.225 1.00 27.88  ? 226 ARG C CD  1 
ATOM   9288  N NE  . ARG C 1 226 ? 109.617 129.549 100.663 1.00 27.88  ? 226 ARG C NE  1 
ATOM   9289  C CZ  . ARG C 1 226 ? 110.394 129.201 101.679 1.00 27.88  ? 226 ARG C CZ  1 
ATOM   9290  N NH1 . ARG C 1 226 ? 110.154 128.113 102.392 1.00 27.88  ? 226 ARG C NH1 1 
ATOM   9291  N NH2 . ARG C 1 226 ? 111.438 129.962 101.988 1.00 27.88  ? 226 ARG C NH2 1 
ATOM   9292  N N   . GLY C 1 227 ? 110.085 125.560 95.149  1.00 28.38  ? 227 GLY C N   1 
ATOM   9293  C CA  . GLY C 1 227 ? 110.114 125.536 93.704  1.00 28.38  ? 227 GLY C CA  1 
ATOM   9294  C C   . GLY C 1 227 ? 111.303 126.202 93.044  1.00 28.38  ? 227 GLY C C   1 
ATOM   9295  O O   . GLY C 1 227 ? 111.392 126.177 91.812  1.00 28.38  ? 227 GLY C O   1 
ATOM   9296  N N   . GLN C 1 228 ? 112.221 126.787 93.809  1.00 28.71  ? 228 GLN C N   1 
ATOM   9297  C CA  . GLN C 1 228 ? 113.301 127.589 93.251  1.00 28.71  ? 228 GLN C CA  1 
ATOM   9298  C C   . GLN C 1 228 ? 114.660 127.019 93.629  1.00 28.71  ? 228 GLN C C   1 
ATOM   9299  O O   . GLN C 1 228 ? 114.890 126.647 94.782  1.00 28.71  ? 228 GLN C O   1 
ATOM   9300  C CB  . GLN C 1 228 ? 113.210 129.046 93.723  1.00 28.71  ? 228 GLN C CB  1 
ATOM   9301  C CG  . GLN C 1 228 ? 111.845 129.674 93.538  1.00 28.71  ? 228 GLN C CG  1 
ATOM   9302  C CD  . GLN C 1 228 ? 111.417 129.705 92.088  1.00 28.71  ? 228 GLN C CD  1 
ATOM   9303  O OE1 . GLN C 1 228 ? 112.200 130.050 91.205  1.00 28.71  ? 228 GLN C OE1 1 
ATOM   9304  N NE2 . GLN C 1 228 ? 110.169 129.340 91.833  1.00 28.71  ? 228 GLN C NE2 1 
ATOM   9305  N N   . SER C 1 229 ? 115.565 126.969 92.652  1.00 28.14  ? 229 SER C N   1 
ATOM   9306  C CA  . SER C 1 229 ? 116.940 126.553 92.891  1.00 28.14  ? 229 SER C CA  1 
ATOM   9307  C C   . SER C 1 229 ? 117.918 127.719 92.980  1.00 28.14  ? 229 SER C C   1 
ATOM   9308  O O   . SER C 1 229 ? 119.080 127.500 93.334  1.00 28.14  ? 229 SER C O   1 
ATOM   9309  C CB  . SER C 1 229 ? 117.398 125.578 91.800  1.00 28.14  ? 229 SER C CB  1 
ATOM   9310  O OG  . SER C 1 229 ? 117.235 126.133 90.511  1.00 28.14  ? 229 SER C OG  1 
ATOM   9311  N N   . GLY C 1 230 ? 117.483 128.947 92.676  1.00 24.68  ? 230 GLY C N   1 
ATOM   9312  C CA  . GLY C 1 230 ? 118.321 130.111 92.877  1.00 24.68  ? 230 GLY C CA  1 
ATOM   9313  C C   . GLY C 1 230 ? 118.307 130.591 94.319  1.00 24.68  ? 230 GLY C C   1 
ATOM   9314  O O   . GLY C 1 230 ? 117.526 130.126 95.148  1.00 24.68  ? 230 GLY C O   1 
ATOM   9315  N N   . ARG C 1 231 ? 119.191 131.543 94.625  1.00 24.41  ? 231 ARG C N   1 
ATOM   9316  C CA  . ARG C 1 231 ? 119.300 132.051 95.991  1.00 24.41  ? 231 ARG C CA  1 
ATOM   9317  C C   . ARG C 1 231 ? 119.548 133.555 95.978  1.00 24.41  ? 231 ARG C C   1 
ATOM   9318  O O   . ARG C 1 231 ? 119.796 134.158 94.935  1.00 24.41  ? 231 ARG C O   1 
ATOM   9319  C CB  . ARG C 1 231 ? 120.415 131.346 96.779  1.00 24.41  ? 231 ARG C CB  1 
ATOM   9320  C CG  . ARG C 1 231 ? 120.220 129.851 96.985  1.00 24.41  ? 231 ARG C CG  1 
ATOM   9321  C CD  . ARG C 1 231 ? 119.097 129.540 97.961  1.00 24.41  ? 231 ARG C CD  1 
ATOM   9322  N NE  . ARG C 1 231 ? 119.076 128.131 98.335  1.00 24.41  ? 231 ARG C NE  1 
ATOM   9323  C CZ  . ARG C 1 231 ? 118.329 127.204 97.750  1.00 24.41  ? 231 ARG C CZ  1 
ATOM   9324  N NH1 . ARG C 1 231 ? 117.512 127.500 96.754  1.00 24.41  ? 231 ARG C NH1 1 
ATOM   9325  N NH2 . ARG C 1 231 ? 118.406 125.948 98.175  1.00 24.41  ? 231 ARG C NH2 1 
ATOM   9326  N N   . ILE C 1 232 ? 119.470 134.162 97.160  1.00 22.95  ? 232 ILE C N   1 
ATOM   9327  C CA  . ILE C 1 232 ? 119.786 135.573 97.355  1.00 22.95  ? 232 ILE C CA  1 
ATOM   9328  C C   . ILE C 1 232 ? 120.654 135.716 98.600  1.00 22.95  ? 232 ILE C C   1 
ATOM   9329  O O   . ILE C 1 232 ? 120.414 135.053 99.613  1.00 22.95  ? 232 ILE C O   1 
ATOM   9330  C CB  . ILE C 1 232 ? 118.503 136.430 97.462  1.00 22.95  ? 232 ILE C CB  1 
ATOM   9331  C CG1 . ILE C 1 232 ? 117.972 136.765 96.068  1.00 22.95  ? 232 ILE C CG1 1 
ATOM   9332  C CG2 . ILE C 1 232 ? 118.751 137.707 98.244  1.00 22.95  ? 232 ILE C CG2 1 
ATOM   9333  C CD1 . ILE C 1 232 ? 116.568 137.299 96.058  1.00 22.95  ? 232 ILE C CD1 1 
ATOM   9334  N N   . SER C 1 233 ? 121.673 136.568 98.518  1.00 22.54  ? 233 SER C N   1 
ATOM   9335  C CA  . SER C 1 233 ? 122.550 136.875 99.640  1.00 22.54  ? 233 SER C CA  1 
ATOM   9336  C C   . SER C 1 233 ? 122.320 138.309 100.102 1.00 22.54  ? 233 SER C C   1 
ATOM   9337  O O   . SER C 1 233 ? 122.173 139.216 99.279  1.00 22.54  ? 233 SER C O   1 
ATOM   9338  C CB  . SER C 1 233 ? 124.018 136.680 99.259  1.00 22.54  ? 233 SER C CB  1 
ATOM   9339  O OG  . SER C 1 233 ? 124.438 135.354 99.509  1.00 22.54  ? 233 SER C OG  1 
ATOM   9340  N N   . ILE C 1 234 ? 122.309 138.509 101.419 1.00 20.94  ? 234 ILE C N   1 
ATOM   9341  C CA  . ILE C 1 234 ? 121.916 139.772 102.038 1.00 20.94  ? 234 ILE C CA  1 
ATOM   9342  C C   . ILE C 1 234 ? 123.135 140.441 102.661 1.00 20.94  ? 234 ILE C C   1 
ATOM   9343  O O   . ILE C 1 234 ? 123.951 139.785 103.317 1.00 20.94  ? 234 ILE C O   1 
ATOM   9344  C CB  . ILE C 1 234 ? 120.812 139.553 103.093 1.00 20.94  ? 234 ILE C CB  1 
ATOM   9345  C CG1 . ILE C 1 234 ? 119.551 138.978 102.442 1.00 20.94  ? 234 ILE C CG1 1 
ATOM   9346  C CG2 . ILE C 1 234 ? 120.494 140.848 103.826 1.00 20.94  ? 234 ILE C CG2 1 
ATOM   9347  C CD1 . ILE C 1 234 ? 118.893 139.911 101.463 1.00 20.94  ? 234 ILE C CD1 1 
ATOM   9348  N N   . TYR C 1 235 ? 123.250 141.755 102.455 1.00 21.54  ? 235 TYR C N   1 
ATOM   9349  C CA  . TYR C 1 235 ? 124.335 142.567 102.986 1.00 21.54  ? 235 TYR C CA  1 
ATOM   9350  C C   . TYR C 1 235 ? 123.764 143.877 103.515 1.00 21.54  ? 235 TYR C C   1 
ATOM   9351  O O   . TYR C 1 235 ? 122.642 144.267 103.182 1.00 21.54  ? 235 TYR C O   1 
ATOM   9352  C CB  . TYR C 1 235 ? 125.402 142.844 101.919 1.00 21.54  ? 235 TYR C CB  1 
ATOM   9353  C CG  . TYR C 1 235 ? 126.022 141.595 101.345 1.00 21.54  ? 235 TYR C CG  1 
ATOM   9354  C CD1 . TYR C 1 235 ? 125.461 140.959 100.247 1.00 21.54  ? 235 TYR C CD1 1 
ATOM   9355  C CD2 . TYR C 1 235 ? 127.165 141.046 101.907 1.00 21.54  ? 235 TYR C CD2 1 
ATOM   9356  C CE1 . TYR C 1 235 ? 126.022 139.815 99.723  1.00 21.54  ? 235 TYR C CE1 1 
ATOM   9357  C CE2 . TYR C 1 235 ? 127.732 139.904 101.391 1.00 21.54  ? 235 TYR C CE2 1 
ATOM   9358  C CZ  . TYR C 1 235 ? 127.159 139.292 100.300 1.00 21.54  ? 235 TYR C CZ  1 
ATOM   9359  O OH  . TYR C 1 235 ? 127.727 138.154 99.788  1.00 21.54  ? 235 TYR C OH  1 
ATOM   9360  N N   . TRP C 1 236 ? 124.552 144.563 104.343 1.00 23.04  ? 236 TRP C N   1 
ATOM   9361  C CA  . TRP C 1 236 ? 124.116 145.809 104.957 1.00 23.04  ? 236 TRP C CA  1 
ATOM   9362  C C   . TRP C 1 236 ? 125.258 146.818 104.985 1.00 23.04  ? 236 TRP C C   1 
ATOM   9363  O O   . TRP C 1 236 ? 126.434 146.450 104.984 1.00 23.04  ? 236 TRP C O   1 
ATOM   9364  C CB  . TRP C 1 236 ? 123.573 145.570 106.373 1.00 23.04  ? 236 TRP C CB  1 
ATOM   9365  C CG  . TRP C 1 236 ? 124.619 145.402 107.430 1.00 23.04  ? 236 TRP C CG  1 
ATOM   9366  C CD1 . TRP C 1 236 ? 125.237 146.392 108.135 1.00 23.04  ? 236 TRP C CD1 1 
ATOM   9367  C CD2 . TRP C 1 236 ? 125.157 144.168 107.917 1.00 23.04  ? 236 TRP C CD2 1 
ATOM   9368  N NE1 . TRP C 1 236 ? 126.132 145.854 109.022 1.00 23.04  ? 236 TRP C NE1 1 
ATOM   9369  C CE2 . TRP C 1 236 ? 126.101 144.490 108.909 1.00 23.04  ? 236 TRP C CE2 1 
ATOM   9370  C CE3 . TRP C 1 236 ? 124.936 142.825 107.607 1.00 23.04  ? 236 TRP C CE3 1 
ATOM   9371  C CZ2 . TRP C 1 236 ? 126.822 143.518 109.595 1.00 23.04  ? 236 TRP C CZ2 1 
ATOM   9372  C CZ3 . TRP C 1 236 ? 125.651 141.861 108.290 1.00 23.04  ? 236 TRP C CZ3 1 
ATOM   9373  C CH2 . TRP C 1 236 ? 126.584 142.212 109.271 1.00 23.04  ? 236 TRP C CH2 1 
ATOM   9374  N N   . THR C 1 237 ? 124.888 148.099 105.013 1.00 23.96  ? 237 THR C N   1 
ATOM   9375  C CA  . THR C 1 237 ? 125.838 149.208 105.023 1.00 23.96  ? 237 THR C CA  1 
ATOM   9376  C C   . THR C 1 237 ? 125.318 150.328 105.915 1.00 23.96  ? 237 THR C C   1 
ATOM   9377  O O   . THR C 1 237 ? 124.121 150.618 105.922 1.00 23.96  ? 237 THR C O   1 
ATOM   9378  C CB  . THR C 1 237 ? 126.085 149.749 103.603 1.00 23.96  ? 237 THR C CB  1 
ATOM   9379  O OG1 . THR C 1 237 ? 126.483 148.678 102.741 1.00 23.96  ? 237 THR C OG1 1 
ATOM   9380  C CG2 . THR C 1 237 ? 127.175 150.813 103.605 1.00 23.96  ? 237 THR C CG2 1 
ATOM   9381  N N   . ILE C 1 238 ? 126.217 150.966 106.661 1.00 25.16  ? 238 ILE C N   1 
ATOM   9382  C CA  . ILE C 1 238 ? 125.870 152.077 107.541 1.00 25.16  ? 238 ILE C CA  1 
ATOM   9383  C C   . ILE C 1 238 ? 126.498 153.353 106.996 1.00 25.16  ? 238 ILE C C   1 
ATOM   9384  O O   . ILE C 1 238 ? 127.694 153.382 106.686 1.00 25.16  ? 238 ILE C O   1 
ATOM   9385  C CB  . ILE C 1 238 ? 126.315 151.812 108.990 1.00 25.16  ? 238 ILE C CB  1 
ATOM   9386  C CG1 . ILE C 1 238 ? 125.373 150.805 109.647 1.00 25.16  ? 238 ILE C CG1 1 
ATOM   9387  C CG2 . ILE C 1 238 ? 126.337 153.103 109.791 1.00 25.16  ? 238 ILE C CG2 1 
ATOM   9388  C CD1 . ILE C 1 238 ? 125.857 150.287 110.957 1.00 25.16  ? 238 ILE C CD1 1 
ATOM   9389  N N   . VAL C 1 239 ? 125.688 154.403 106.877 1.00 27.25  ? 239 VAL C N   1 
ATOM   9390  C CA  . VAL C 1 239 ? 126.118 155.697 106.353 1.00 27.25  ? 239 VAL C CA  1 
ATOM   9391  C C   . VAL C 1 239 ? 125.998 156.729 107.469 1.00 27.25  ? 239 VAL C C   1 
ATOM   9392  O O   . VAL C 1 239 ? 124.892 156.996 107.959 1.00 27.25  ? 239 VAL C O   1 
ATOM   9393  C CB  . VAL C 1 239 ? 125.295 156.119 105.125 1.00 27.25  ? 239 VAL C CB  1 
ATOM   9394  C CG1 . VAL C 1 239 ? 125.823 157.423 104.550 1.00 27.25  ? 239 VAL C CG1 1 
ATOM   9395  C CG2 . VAL C 1 239 ? 125.308 155.025 104.072 1.00 27.25  ? 239 VAL C CG2 1 
ATOM   9396  N N   . LYS C 1 240 ? 127.132 157.307 107.863 1.00 31.67  ? 240 LYS C N   1 
ATOM   9397  C CA  . LYS C 1 240 ? 127.194 158.324 108.903 1.00 31.67  ? 240 LYS C CA  1 
ATOM   9398  C C   . LYS C 1 240 ? 126.741 159.681 108.367 1.00 31.67  ? 240 LYS C C   1 
ATOM   9399  O O   . LYS C 1 240 ? 126.715 159.900 107.154 1.00 31.67  ? 240 LYS C O   1 
ATOM   9400  C CB  . LYS C 1 240 ? 128.615 158.425 109.450 1.00 31.67  ? 240 LYS C CB  1 
ATOM   9401  C CG  . LYS C 1 240 ? 129.318 157.095 109.627 1.00 31.67  ? 240 LYS C CG  1 
ATOM   9402  C CD  . LYS C 1 240 ? 128.962 156.446 110.951 1.00 31.67  ? 240 LYS C CD  1 
ATOM   9403  C CE  . LYS C 1 240 ? 129.237 157.375 112.118 1.00 31.67  ? 240 LYS C CE  1 
ATOM   9404  N NZ  . LYS C 1 240 ? 128.507 156.952 113.343 1.00 31.67  ? 240 LYS C NZ  1 
ATOM   9405  N N   . PRO C 1 241 ? 126.363 160.607 109.253 1.00 32.73  ? 241 PRO C N   1 
ATOM   9406  C CA  . PRO C 1 241 ? 125.980 161.947 108.793 1.00 32.73  ? 241 PRO C CA  1 
ATOM   9407  C C   . PRO C 1 241 ? 127.115 162.631 108.046 1.00 32.73  ? 241 PRO C C   1 
ATOM   9408  O O   . PRO C 1 241 ? 128.276 162.579 108.455 1.00 32.73  ? 241 PRO C O   1 
ATOM   9409  C CB  . PRO C 1 241 ? 125.639 162.683 110.093 1.00 32.73  ? 241 PRO C CB  1 
ATOM   9410  C CG  . PRO C 1 241 ? 125.287 161.611 111.051 1.00 32.73  ? 241 PRO C CG  1 
ATOM   9411  C CD  . PRO C 1 241 ? 126.161 160.451 110.703 1.00 32.73  ? 241 PRO C CD  1 
ATOM   9412  N N   . GLY C 1 242 ? 126.763 163.282 106.942 1.00 33.37  ? 242 GLY C N   1 
ATOM   9413  C CA  . GLY C 1 242 ? 127.730 163.951 106.102 1.00 33.37  ? 242 GLY C CA  1 
ATOM   9414  C C   . GLY C 1 242 ? 128.411 163.074 105.075 1.00 33.37  ? 242 GLY C C   1 
ATOM   9415  O O   . GLY C 1 242 ? 129.200 163.590 104.275 1.00 33.37  ? 242 GLY C O   1 
ATOM   9416  N N   . ASP C 1 243 ? 128.137 161.773 105.067 1.00 33.21  ? 243 ASP C N   1 
ATOM   9417  C CA  . ASP C 1 243 ? 128.716 160.854 104.104 1.00 33.21  ? 243 ASP C CA  1 
ATOM   9418  C C   . ASP C 1 243 ? 127.755 160.652 102.934 1.00 33.21  ? 243 ASP C C   1 
ATOM   9419  O O   . ASP C 1 243 ? 126.694 161.271 102.850 1.00 33.21  ? 243 ASP C O   1 
ATOM   9420  C CB  . ASP C 1 243 ? 129.064 159.524 104.775 1.00 33.21  ? 243 ASP C CB  1 
ATOM   9421  C CG  . ASP C 1 243 ? 130.297 158.874 104.181 1.00 33.21  ? 243 ASP C CG  1 
ATOM   9422  O OD1 . ASP C 1 243 ? 130.479 158.950 102.950 1.00 33.21  ? 243 ASP C OD1 1 
ATOM   9423  O OD2 . ASP C 1 243 ? 131.080 158.276 104.945 1.00 33.21  ? 243 ASP C OD2 1 
ATOM   9424  N N   . VAL C 1 244 ? 128.138 159.765 102.018 1.00 31.40  ? 244 VAL C N   1 
ATOM   9425  C CA  . VAL C 1 244 ? 127.367 159.521 100.806 1.00 31.40  ? 244 VAL C CA  1 
ATOM   9426  C C   . VAL C 1 244 ? 127.486 158.046 100.446 1.00 31.40  ? 244 VAL C C   1 
ATOM   9427  O O   . VAL C 1 244 ? 128.517 157.413 100.682 1.00 31.40  ? 244 VAL C O   1 
ATOM   9428  C CB  . VAL C 1 244 ? 127.843 160.438 99.652  1.00 31.40  ? 244 VAL C CB  1 
ATOM   9429  C CG1 . VAL C 1 244 ? 129.301 160.177 99.327  1.00 31.40  ? 244 VAL C CG1 1 
ATOM   9430  C CG2 . VAL C 1 244 ? 126.975 160.264 98.422  1.00 31.40  ? 244 VAL C CG2 1 
ATOM   9431  N N   . LEU C 1 245 ? 126.412 157.494 99.888  1.00 27.43  ? 245 LEU C N   1 
ATOM   9432  C CA  . LEU C 1 245 ? 126.368 156.112 99.437  1.00 27.43  ? 245 LEU C CA  1 
ATOM   9433  C C   . LEU C 1 245 ? 126.342 156.083 97.916  1.00 27.43  ? 245 LEU C C   1 
ATOM   9434  O O   . LEU C 1 245 ? 125.590 156.838 97.293  1.00 27.43  ? 245 LEU C O   1 
ATOM   9435  C CB  . LEU C 1 245 ? 125.137 155.399 100.000 1.00 27.43  ? 245 LEU C CB  1 
ATOM   9436  C CG  . LEU C 1 245 ? 124.890 153.961 99.545  1.00 27.43  ? 245 LEU C CG  1 
ATOM   9437  C CD1 . LEU C 1 245 ? 125.668 153.000 100.420 1.00 27.43  ? 245 LEU C CD1 1 
ATOM   9438  C CD2 . LEU C 1 245 ? 123.409 153.638 99.571  1.00 27.43  ? 245 LEU C CD2 1 
ATOM   9439  N N   . VAL C 1 246 ? 127.165 155.223 97.321  1.00 26.87  ? 246 VAL C N   1 
ATOM   9440  C CA  . VAL C 1 246 ? 127.191 155.024 95.877  1.00 26.87  ? 246 VAL C CA  1 
ATOM   9441  C C   . VAL C 1 246 ? 126.982 153.544 95.591  1.00 26.87  ? 246 VAL C C   1 
ATOM   9442  O O   . VAL C 1 246 ? 127.643 152.688 96.195  1.00 26.87  ? 246 VAL C O   1 
ATOM   9443  C CB  . VAL C 1 246 ? 128.503 155.528 95.246  1.00 26.87  ? 246 VAL C CB  1 
ATOM   9444  C CG1 . VAL C 1 246 ? 128.560 155.158 93.776  1.00 26.87  ? 246 VAL C CG1 1 
ATOM   9445  C CG2 . VAL C 1 246 ? 128.630 157.031 95.411  1.00 26.87  ? 246 VAL C CG2 1 
ATOM   9446  N N   . ILE C 1 247 ? 126.056 153.249 94.682  1.00 26.40  ? 247 ILE C N   1 
ATOM   9447  C CA  . ILE C 1 247 ? 125.775 151.894 94.227  1.00 26.40  ? 247 ILE C CA  1 
ATOM   9448  C C   . ILE C 1 247 ? 126.090 151.818 92.740  1.00 26.40  ? 247 ILE C C   1 
ATOM   9449  O O   . ILE C 1 247 ? 125.566 152.609 91.947  1.00 26.40  ? 247 ILE C O   1 
ATOM   9450  C CB  . ILE C 1 247 ? 124.314 151.490 94.497  1.00 26.40  ? 247 ILE C CB  1 
ATOM   9451  C CG1 . ILE C 1 247 ? 123.999 151.582 95.991  1.00 26.40  ? 247 ILE C CG1 1 
ATOM   9452  C CG2 . ILE C 1 247 ? 124.046 150.088 93.982  1.00 26.40  ? 247 ILE C CG2 1 
ATOM   9453  C CD1 . ILE C 1 247 ? 122.529 151.530 96.309  1.00 26.40  ? 247 ILE C CD1 1 
ATOM   9454  N N   . ASN C 1 248 ? 126.940 150.863 92.368  1.00 27.92  ? 248 ASN C N   1 
ATOM   9455  C CA  . ASN C 1 248 ? 127.400 150.689 90.996  1.00 27.92  ? 248 ASN C CA  1 
ATOM   9456  C C   . ASN C 1 248 ? 127.307 149.210 90.652  1.00 27.92  ? 248 ASN C C   1 
ATOM   9457  O O   . ASN C 1 248 ? 127.953 148.381 91.295  1.00 27.92  ? 248 ASN C O   1 
ATOM   9458  C CB  . ASN C 1 248 ? 128.837 151.203 90.838  1.00 27.92  ? 248 ASN C CB  1 
ATOM   9459  C CG  . ASN C 1 248 ? 129.355 151.078 89.421  1.00 27.92  ? 248 ASN C CG  1 
ATOM   9460  O OD1 . ASN C 1 248 ? 129.924 150.055 89.049  1.00 27.92  ? 248 ASN C OD1 1 
ATOM   9461  N ND2 . ASN C 1 248 ? 129.183 152.128 88.631  1.00 27.92  ? 248 ASN C ND2 1 
ATOM   9462  N N   . SER C 1 249 ? 126.516 148.876 89.640  1.00 28.84  ? 249 SER C N   1 
ATOM   9463  C CA  . SER C 1 249 ? 126.267 147.467 89.369  1.00 28.84  ? 249 SER C CA  1 
ATOM   9464  C C   . SER C 1 249 ? 125.977 147.241 87.898  1.00 28.84  ? 249 SER C C   1 
ATOM   9465  O O   . SER C 1 249 ? 125.349 148.076 87.245  1.00 28.84  ? 249 SER C O   1 
ATOM   9466  C CB  . SER C 1 249 ? 125.097 146.938 90.204  1.00 28.84  ? 249 SER C CB  1 
ATOM   9467  O OG  . SER C 1 249 ? 124.672 145.672 89.734  1.00 28.84  ? 249 SER C OG  1 
ATOM   9468  N N   . ASN C 1 250 ? 126.416 146.090 87.386  1.00 30.42  ? 250 ASN C N   1 
ATOM   9469  C CA  . ASN C 1 250 ? 126.092 145.724 86.010  1.00 30.42  ? 250 ASN C CA  1 
ATOM   9470  C C   . ASN C 1 250 ? 125.321 144.409 85.926  1.00 30.42  ? 250 ASN C C   1 
ATOM   9471  O O   . ASN C 1 250 ? 125.299 143.771 84.869  1.00 30.42  ? 250 ASN C O   1 
ATOM   9472  C CB  . ASN C 1 250 ? 127.355 145.692 85.142  1.00 30.42  ? 250 ASN C CB  1 
ATOM   9473  C CG  . ASN C 1 250 ? 128.188 144.446 85.346  1.00 30.42  ? 250 ASN C CG  1 
ATOM   9474  O OD1 . ASN C 1 250 ? 128.341 143.959 86.462  1.00 30.42  ? 250 ASN C OD1 1 
ATOM   9475  N ND2 . ASN C 1 250 ? 128.747 143.933 84.260  1.00 30.42  ? 250 ASN C ND2 1 
ATOM   9476  N N   . GLY C 1 251 ? 124.662 144.010 87.010  1.00 28.11  ? 251 GLY C N   1 
ATOM   9477  C CA  . GLY C 1 251 ? 123.826 142.827 87.008  1.00 28.11  ? 251 GLY C CA  1 
ATOM   9478  C C   . GLY C 1 251 ? 123.643 142.220 88.383  1.00 28.11  ? 251 GLY C C   1 
ATOM   9479  O O   . GLY C 1 251 ? 124.507 142.372 89.250  1.00 28.11  ? 251 GLY C O   1 
ATOM   9480  N N   . ASN C 1 252 ? 122.506 141.549 88.592  1.00 26.75  ? 252 ASN C N   1 
ATOM   9481  C CA  . ASN C 1 252 ? 122.239 140.734 89.780  1.00 26.75  ? 252 ASN C CA  1 
ATOM   9482  C C   . ASN C 1 252 ? 122.054 141.567 91.048  1.00 26.75  ? 252 ASN C C   1 
ATOM   9483  O O   . ASN C 1 252 ? 122.342 141.094 92.147  1.00 26.75  ? 252 ASN C O   1 
ATOM   9484  C CB  . ASN C 1 252 ? 123.339 139.687 90.007  1.00 26.75  ? 252 ASN C CB  1 
ATOM   9485  C CG  . ASN C 1 252 ? 123.601 138.832 88.783  1.00 26.75  ? 252 ASN C CG  1 
ATOM   9486  O OD1 . ASN C 1 252 ? 124.095 139.315 87.766  1.00 26.75  ? 252 ASN C OD1 1 
ATOM   9487  N ND2 . ASN C 1 252 ? 123.274 137.551 88.877  1.00 26.75  ? 252 ASN C ND2 1 
ATOM   9488  N N   . LEU C 1 253 ? 121.563 142.798 90.933  1.00 24.03  ? 253 LEU C N   1 
ATOM   9489  C CA  . LEU C 1 253 ? 121.392 143.663 92.094  1.00 24.03  ? 253 LEU C CA  1 
ATOM   9490  C C   . LEU C 1 253 ? 119.974 143.561 92.644  1.00 24.03  ? 253 LEU C C   1 
ATOM   9491  O O   . LEU C 1 253 ? 119.000 143.653 91.891  1.00 24.03  ? 253 LEU C O   1 
ATOM   9492  C CB  . LEU C 1 253 ? 121.713 145.117 91.744  1.00 24.03  ? 253 LEU C CB  1 
ATOM   9493  C CG  . LEU C 1 253 ? 121.217 146.193 92.719  1.00 24.03  ? 253 LEU C CG  1 
ATOM   9494  C CD1 . LEU C 1 253 ? 122.032 146.200 94.002  1.00 24.03  ? 253 LEU C CD1 1 
ATOM   9495  C CD2 . LEU C 1 253 ? 121.232 147.566 92.068  1.00 24.03  ? 253 LEU C CD2 1 
ATOM   9496  N N   . ILE C 1 254 ? 119.869 143.356 93.953  1.00 22.63  ? 254 ILE C N   1 
ATOM   9497  C CA  . ILE C 1 254 ? 118.612 143.473 94.684  1.00 22.63  ? 254 ILE C CA  1 
ATOM   9498  C C   . ILE C 1 254 ? 118.688 144.795 95.441  1.00 22.63  ? 254 ILE C C   1 
ATOM   9499  O O   . ILE C 1 254 ? 119.334 144.889 96.486  1.00 22.63  ? 254 ILE C O   1 
ATOM   9500  C CB  . ILE C 1 254 ? 118.381 142.286 95.625  1.00 22.63  ? 254 ILE C CB  1 
ATOM   9501  C CG1 . ILE C 1 254 ? 118.610 140.959 94.894  1.00 22.63  ? 254 ILE C CG1 1 
ATOM   9502  C CG2 . ILE C 1 254 ? 116.985 142.341 96.228  1.00 22.63  ? 254 ILE C CG2 1 
ATOM   9503  C CD1 . ILE C 1 254 ? 117.518 140.592 93.912  1.00 22.63  ? 254 ILE C CD1 1 
ATOM   9504  N N   . ALA C 1 255 ? 118.032 145.820 94.914  1.00 22.96  ? 255 ALA C N   1 
ATOM   9505  C CA  . ALA C 1 255 ? 118.223 147.182 95.379  1.00 22.96  ? 255 ALA C CA  1 
ATOM   9506  C C   . ALA C 1 255 ? 117.433 147.467 96.657  1.00 22.96  ? 255 ALA C C   1 
ATOM   9507  O O   . ALA C 1 255 ? 116.386 146.865 96.899  1.00 22.96  ? 255 ALA C O   1 
ATOM   9508  C CB  . ALA C 1 255 ? 117.806 148.165 94.295  1.00 22.96  ? 255 ALA C CB  1 
ATOM   9509  N N   . PRO C 1 256 ? 117.921 148.380 97.491  1.00 22.97  ? 256 PRO C N   1 
ATOM   9510  C CA  . PRO C 1 256 ? 117.113 148.870 98.610  1.00 22.97  ? 256 PRO C CA  1 
ATOM   9511  C C   . PRO C 1 256 ? 116.046 149.846 98.138  1.00 22.97  ? 256 PRO C C   1 
ATOM   9512  O O   . PRO C 1 256 ? 116.153 150.469 97.081  1.00 22.97  ? 256 PRO C O   1 
ATOM   9513  C CB  . PRO C 1 256 ? 118.140 149.571 99.503  1.00 22.97  ? 256 PRO C CB  1 
ATOM   9514  C CG  . PRO C 1 256 ? 119.179 150.037 98.560  1.00 22.97  ? 256 PRO C CG  1 
ATOM   9515  C CD  . PRO C 1 256 ? 119.244 149.027 97.444  1.00 22.97  ? 256 PRO C CD  1 
ATOM   9516  N N   . ARG C 1 257 ? 114.999 149.966 98.948  1.00 23.16  ? 257 ARG C N   1 
ATOM   9517  C CA  . ARG C 1 257 ? 113.935 150.932 98.710  1.00 23.16  ? 257 ARG C CA  1 
ATOM   9518  C C   . ARG C 1 257 ? 114.013 152.131 99.644  1.00 23.16  ? 257 ARG C C   1 
ATOM   9519  O O   . ARG C 1 257 ? 113.211 153.058 99.508  1.00 23.16  ? 257 ARG C O   1 
ATOM   9520  C CB  . ARG C 1 257 ? 112.566 150.259 98.853  1.00 23.16  ? 257 ARG C CB  1 
ATOM   9521  C CG  . ARG C 1 257 ? 112.228 149.276 97.750  1.00 23.16  ? 257 ARG C CG  1 
ATOM   9522  C CD  . ARG C 1 257 ? 110.803 148.780 97.885  1.00 23.16  ? 257 ARG C CD  1 
ATOM   9523  N NE  . ARG C 1 257 ? 110.500 147.690 96.966  1.00 23.16  ? 257 ARG C NE  1 
ATOM   9524  C CZ  . ARG C 1 257 ? 110.006 147.848 95.746  1.00 23.16  ? 257 ARG C CZ  1 
ATOM   9525  N NH1 . ARG C 1 257 ? 109.762 149.048 95.249  1.00 23.16  ? 257 ARG C NH1 1 
ATOM   9526  N NH2 . ARG C 1 257 ? 109.743 146.774 95.010  1.00 23.16  ? 257 ARG C NH2 1 
ATOM   9527  N N   . GLY C 1 258 ? 114.963 152.134 100.572 1.00 23.85  ? 258 GLY C N   1 
ATOM   9528  C CA  . GLY C 1 258 ? 115.044 153.175 101.580 1.00 23.85  ? 258 GLY C CA  1 
ATOM   9529  C C   . GLY C 1 258 ? 116.045 152.775 102.647 1.00 23.85  ? 258 GLY C C   1 
ATOM   9530  O O   . GLY C 1 258 ? 116.929 151.956 102.400 1.00 23.85  ? 258 GLY C O   1 
ATOM   9531  N N   . PHE C 1 259 ? 115.889 153.353 103.835 1.00 23.39  ? 259 PHE C N   1 
ATOM   9532  C CA  . PHE C 1 259 ? 116.824 153.078 104.920 1.00 23.39  ? 259 PHE C CA  1 
ATOM   9533  C C   . PHE C 1 259 ? 116.087 152.874 106.237 1.00 23.39  ? 259 PHE C C   1 
ATOM   9534  O O   . PHE C 1 259 ? 114.967 153.348 106.434 1.00 23.39  ? 259 PHE C O   1 
ATOM   9535  C CB  . PHE C 1 259 ? 117.880 154.194 105.062 1.00 23.39  ? 259 PHE C CB  1 
ATOM   9536  C CG  . PHE C 1 259 ? 117.328 155.511 105.539 1.00 23.39  ? 259 PHE C CG  1 
ATOM   9537  C CD1 . PHE C 1 259 ? 117.252 155.803 106.891 1.00 23.39  ? 259 PHE C CD1 1 
ATOM   9538  C CD2 . PHE C 1 259 ? 116.902 156.465 104.632 1.00 23.39  ? 259 PHE C CD2 1 
ATOM   9539  C CE1 . PHE C 1 259 ? 116.747 157.009 107.326 1.00 23.39  ? 259 PHE C CE1 1 
ATOM   9540  C CE2 . PHE C 1 259 ? 116.400 157.675 105.063 1.00 23.39  ? 259 PHE C CE2 1 
ATOM   9541  C CZ  . PHE C 1 259 ? 116.323 157.948 106.410 1.00 23.39  ? 259 PHE C CZ  1 
ATOM   9542  N N   . PHE C 1 260 ? 116.746 152.153 107.142 1.00 24.95  ? 260 PHE C N   1 
ATOM   9543  C CA  . PHE C 1 260 ? 116.284 151.954 108.508 1.00 24.95  ? 260 PHE C CA  1 
ATOM   9544  C C   . PHE C 1 260 ? 117.003 152.915 109.446 1.00 24.95  ? 260 PHE C C   1 
ATOM   9545  O O   . PHE C 1 260 ? 118.207 153.146 109.310 1.00 24.95  ? 260 PHE C O   1 
ATOM   9546  C CB  . PHE C 1 260 ? 116.541 150.520 108.983 1.00 24.95  ? 260 PHE C CB  1 
ATOM   9547  C CG  . PHE C 1 260 ? 115.713 149.478 108.289 1.00 24.95  ? 260 PHE C CG  1 
ATOM   9548  C CD1 . PHE C 1 260 ? 114.462 149.133 108.773 1.00 24.95  ? 260 PHE C CD1 1 
ATOM   9549  C CD2 . PHE C 1 260 ? 116.198 148.820 107.171 1.00 24.95  ? 260 PHE C CD2 1 
ATOM   9550  C CE1 . PHE C 1 260 ? 113.705 148.167 108.144 1.00 24.95  ? 260 PHE C CE1 1 
ATOM   9551  C CE2 . PHE C 1 260 ? 115.444 147.855 106.538 1.00 24.95  ? 260 PHE C CE2 1 
ATOM   9552  C CZ  . PHE C 1 260 ? 114.197 147.527 107.027 1.00 24.95  ? 260 PHE C CZ  1 
ATOM   9553  N N   . LYS C 1 261 ? 116.263 153.469 110.399 1.00 30.77  ? 261 LYS C N   1 
ATOM   9554  C CA  . LYS C 1 261 ? 116.893 154.195 111.492 1.00 30.77  ? 261 LYS C CA  1 
ATOM   9555  C C   . LYS C 1 261 ? 117.570 153.216 112.440 1.00 30.77  ? 261 LYS C C   1 
ATOM   9556  O O   . LYS C 1 261 ? 117.063 152.121 112.694 1.00 30.77  ? 261 LYS C O   1 
ATOM   9557  C CB  . LYS C 1 261 ? 115.865 155.030 112.248 1.00 30.77  ? 261 LYS C CB  1 
ATOM   9558  C CG  . LYS C 1 261 ? 115.335 156.214 111.471 1.00 30.77  ? 261 LYS C CG  1 
ATOM   9559  C CD  . LYS C 1 261 ? 115.638 157.511 112.194 1.00 30.77  ? 261 LYS C CD  1 
ATOM   9560  C CE  . LYS C 1 261 ? 114.464 158.466 112.117 1.00 30.77  ? 261 LYS C CE  1 
ATOM   9561  N NZ  . LYS C 1 261 ? 113.896 158.509 110.746 1.00 30.77  ? 261 LYS C NZ  1 
ATOM   9562  N N   . ILE C 1 262 ? 118.729 153.606 112.958 1.00 32.64  ? 262 ILE C N   1 
ATOM   9563  C CA  . ILE C 1 262 ? 119.482 152.783 113.895 1.00 32.64  ? 262 ILE C CA  1 
ATOM   9564  C C   . ILE C 1 262 ? 119.744 153.607 115.147 1.00 32.64  ? 262 ILE C C   1 
ATOM   9565  O O   . ILE C 1 262 ? 120.200 154.752 115.061 1.00 32.64  ? 262 ILE C O   1 
ATOM   9566  C CB  . ILE C 1 262 ? 120.794 152.260 113.276 1.00 32.64  ? 262 ILE C CB  1 
ATOM   9567  C CG1 . ILE C 1 262 ? 121.620 151.506 114.319 1.00 32.64  ? 262 ILE C CG1 1 
ATOM   9568  C CG2 . ILE C 1 262 ? 121.586 153.382 112.630 1.00 32.64  ? 262 ILE C CG2 1 
ATOM   9569  C CD1 . ILE C 1 262 ? 122.605 150.534 113.723 1.00 32.64  ? 262 ILE C CD1 1 
ATOM   9570  N N   . ARG C 1 263 ? 119.431 153.035 116.305 1.00 35.14  ? 263 ARG C N   1 
ATOM   9571  C CA  . ARG C 1 263 ? 119.475 153.756 117.565 1.00 35.14  ? 263 ARG C CA  1 
ATOM   9572  C C   . ARG C 1 263 ? 120.354 153.014 118.557 1.00 35.14  ? 263 ARG C C   1 
ATOM   9573  O O   . ARG C 1 263 ? 120.681 151.838 118.379 1.00 35.14  ? 263 ARG C O   1 
ATOM   9574  C CB  . ARG C 1 263 ? 118.069 153.944 118.151 1.00 35.14  ? 263 ARG C CB  1 
ATOM   9575  C CG  . ARG C 1 263 ? 117.139 154.746 117.263 1.00 35.14  ? 263 ARG C CG  1 
ATOM   9576  C CD  . ARG C 1 263 ? 115.802 155.004 117.934 1.00 35.14  ? 263 ARG C CD  1 
ATOM   9577  N NE  . ARG C 1 263 ? 114.697 154.868 116.993 1.00 35.14  ? 263 ARG C NE  1 
ATOM   9578  C CZ  . ARG C 1 263 ? 114.234 155.848 116.228 1.00 35.14  ? 263 ARG C CZ  1 
ATOM   9579  N NH1 . ARG C 1 263 ? 114.750 157.065 116.276 1.00 35.14  ? 263 ARG C NH1 1 
ATOM   9580  N NH2 . ARG C 1 263 ? 113.229 155.599 115.393 1.00 35.14  ? 263 ARG C NH2 1 
ATOM   9581  N N   . THR C 1 264 ? 120.746 153.731 119.602 1.00 38.09  ? 264 THR C N   1 
ATOM   9582  C CA  . THR C 1 264 ? 121.459 153.168 120.739 1.00 38.09  ? 264 THR C CA  1 
ATOM   9583  C C   . THR C 1 264 ? 120.495 153.078 121.912 1.00 38.09  ? 264 THR C C   1 
ATOM   9584  O O   . THR C 1 264 ? 119.820 154.059 122.238 1.00 38.09  ? 264 THR C O   1 
ATOM   9585  C CB  . THR C 1 264 ? 122.671 154.025 121.111 1.00 38.09  ? 264 THR C CB  1 
ATOM   9586  O OG1 . THR C 1 264 ? 123.599 154.048 120.020 1.00 38.09  ? 264 THR C OG1 1 
ATOM   9587  C CG2 . THR C 1 264 ? 123.359 153.469 122.344 1.00 38.09  ? 264 THR C CG2 1 
ATOM   9588  N N   . GLY C 1 265 ? 120.425 151.913 122.534 1.00 36.22  ? 265 GLY C N   1 
ATOM   9589  C CA  . GLY C 1 265 ? 119.496 151.733 123.625 1.00 36.22  ? 265 GLY C CA  1 
ATOM   9590  C C   . GLY C 1 265 ? 119.732 150.441 124.367 1.00 36.22  ? 265 GLY C C   1 
ATOM   9591  O O   . GLY C 1 265 ? 120.801 149.838 124.275 1.00 36.22  ? 265 GLY C O   1 
ATOM   9592  N N   . ARG C 1 266 ? 118.705 150.019 125.100 1.00 34.29  ? 266 ARG C N   1 
ATOM   9593  C CA  . ARG C 1 266 ? 118.783 148.863 125.985 1.00 34.29  ? 266 ARG C CA  1 
ATOM   9594  C C   . ARG C 1 266 ? 117.877 147.718 125.531 1.00 34.29  ? 266 ARG C C   1 
ATOM   9595  O O   . ARG C 1 266 ? 117.446 146.900 126.345 1.00 34.29  ? 266 ARG C O   1 
ATOM   9596  C CB  . ARG C 1 266 ? 118.462 149.286 127.420 1.00 34.29  ? 266 ARG C CB  1 
ATOM   9597  C CG  . ARG C 1 266 ? 116.989 149.575 127.686 1.00 34.29  ? 266 ARG C CG  1 
ATOM   9598  C CD  . ARG C 1 266 ? 116.742 149.915 129.147 1.00 34.29  ? 266 ARG C CD  1 
ATOM   9599  N NE  . ARG C 1 266 ? 115.332 150.159 129.431 1.00 34.29  ? 266 ARG C NE  1 
ATOM   9600  C CZ  . ARG C 1 266 ? 114.390 149.224 129.443 1.00 34.29  ? 266 ARG C CZ  1 
ATOM   9601  N NH1 . ARG C 1 266 ? 114.673 147.953 129.210 1.00 34.29  ? 266 ARG C NH1 1 
ATOM   9602  N NH2 . ARG C 1 266 ? 113.133 149.573 129.702 1.00 34.29  ? 266 ARG C NH2 1 
ATOM   9603  N N   . SER C 1 267 ? 117.604 147.626 124.232 1.00 28.75  ? 267 SER C N   1 
ATOM   9604  C CA  . SER C 1 267 ? 116.750 146.577 123.689 1.00 28.75  ? 267 SER C CA  1 
ATOM   9605  C C   . SER C 1 267 ? 117.551 145.305 123.416 1.00 28.75  ? 267 SER C C   1 
ATOM   9606  O O   . SER C 1 267 ? 118.771 145.336 123.250 1.00 28.75  ? 267 SER C O   1 
ATOM   9607  C CB  . SER C 1 267 ? 116.069 147.050 122.405 1.00 28.75  ? 267 SER C CB  1 
ATOM   9608  O OG  . SER C 1 267 ? 115.018 147.955 122.681 1.00 28.75  ? 267 SER C OG  1 
ATOM   9609  N N   . SER C 1 268 ? 116.842 144.177 123.361 1.00 26.95  ? 268 SER C N   1 
ATOM   9610  C CA  . SER C 1 268 ? 117.474 142.877 123.159 1.00 26.95  ? 268 SER C CA  1 
ATOM   9611  C C   . SER C 1 268 ? 116.448 141.899 122.591 1.00 26.95  ? 268 SER C C   1 
ATOM   9612  O O   . SER C 1 268 ? 115.294 142.253 122.340 1.00 26.95  ? 268 SER C O   1 
ATOM   9613  C CB  . SER C 1 268 ? 118.083 142.353 124.462 1.00 26.95  ? 268 SER C CB  1 
ATOM   9614  O OG  . SER C 1 268 ? 118.958 141.269 124.216 1.00 26.95  ? 268 SER C OG  1 
ATOM   9615  N N   . ILE C 1 269 ? 116.886 140.652 122.400 1.00 25.07  ? 269 ILE C N   1 
ATOM   9616  C CA  . ILE C 1 269 ? 116.073 139.588 121.820 1.00 25.07  ? 269 ILE C CA  1 
ATOM   9617  C C   . ILE C 1 269 ? 116.252 138.321 122.651 1.00 25.07  ? 269 ILE C C   1 
ATOM   9618  O O   . ILE C 1 269 ? 117.300 138.106 123.265 1.00 25.07  ? 269 ILE C O   1 
ATOM   9619  C CB  . ILE C 1 269 ? 116.449 139.345 120.336 1.00 25.07  ? 269 ILE C CB  1 
ATOM   9620  C CG1 . ILE C 1 269 ? 115.468 138.386 119.661 1.00 25.07  ? 269 ILE C CG1 1 
ATOM   9621  C CG2 . ILE C 1 269 ? 117.878 138.830 120.207 1.00 25.07  ? 269 ILE C CG2 1 
ATOM   9622  C CD1 . ILE C 1 269 ? 115.491 138.464 118.154 1.00 25.07  ? 269 ILE C CD1 1 
ATOM   9623  N N   . MET C 1 270 ? 115.219 137.476 122.670 1.00 27.80  ? 270 MET C N   1 
ATOM   9624  C CA  . MET C 1 270 ? 115.232 136.257 123.470 1.00 27.80  ? 270 MET C CA  1 
ATOM   9625  C C   . MET C 1 270 ? 114.411 135.168 122.788 1.00 27.80  ? 270 MET C C   1 
ATOM   9626  O O   . MET C 1 270 ? 113.384 135.454 122.170 1.00 27.80  ? 270 MET C O   1 
ATOM   9627  C CB  . MET C 1 270 ? 114.690 136.520 124.882 1.00 27.80  ? 270 MET C CB  1 
ATOM   9628  C CG  . MET C 1 270 ? 114.766 135.331 125.830 1.00 27.80  ? 270 MET C CG  1 
ATOM   9629  S SD  . MET C 1 270 ? 113.901 135.601 127.394 1.00 27.80  ? 270 MET C SD  1 
ATOM   9630  C CE  . MET C 1 270 ? 115.157 136.456 128.338 1.00 27.80  ? 270 MET C CE  1 
ATOM   9631  N N   . ARG C 1 271 ? 114.862 133.922 122.920 1.00 27.33  ? 271 ARG C N   1 
ATOM   9632  C CA  . ARG C 1 271 ? 114.147 132.756 122.411 1.00 27.33  ? 271 ARG C CA  1 
ATOM   9633  C C   . ARG C 1 271 ? 113.387 132.103 123.561 1.00 27.33  ? 271 ARG C C   1 
ATOM   9634  O O   . ARG C 1 271 ? 113.988 131.750 124.581 1.00 27.33  ? 271 ARG C O   1 
ATOM   9635  C CB  . ARG C 1 271 ? 115.109 131.750 121.778 1.00 27.33  ? 271 ARG C CB  1 
ATOM   9636  C CG  . ARG C 1 271 ? 115.908 132.273 120.597 1.00 27.33  ? 271 ARG C CG  1 
ATOM   9637  C CD  . ARG C 1 271 ? 116.730 131.161 119.960 1.00 27.33  ? 271 ARG C CD  1 
ATOM   9638  N NE  . ARG C 1 271 ? 117.596 131.651 118.893 1.00 27.33  ? 271 ARG C NE  1 
ATOM   9639  C CZ  . ARG C 1 271 ? 118.868 131.989 119.053 1.00 27.33  ? 271 ARG C CZ  1 
ATOM   9640  N NH1 . ARG C 1 271 ? 119.468 131.892 120.227 1.00 27.33  ? 271 ARG C NH1 1 
ATOM   9641  N NH2 . ARG C 1 271 ? 119.557 132.436 118.007 1.00 27.33  ? 271 ARG C NH2 1 
ATOM   9642  N N   . SER C 1 272 ? 112.077 131.936 123.396 1.00 30.11  ? 272 SER C N   1 
ATOM   9643  C CA  . SER C 1 272 ? 111.255 131.371 124.457 1.00 30.11  ? 272 SER C CA  1 
ATOM   9644  C C   . SER C 1 272 ? 109.916 130.930 123.887 1.00 30.11  ? 272 SER C C   1 
ATOM   9645  O O   . SER C 1 272 ? 109.444 131.474 122.887 1.00 30.11  ? 272 SER C O   1 
ATOM   9646  C CB  . SER C 1 272 ? 111.036 132.378 125.593 1.00 30.11  ? 272 SER C CB  1 
ATOM   9647  O OG  . SER C 1 272 ? 110.189 131.844 126.593 1.00 30.11  ? 272 SER C OG  1 
ATOM   9648  N N   . ASP C 1 273 ? 109.306 129.944 124.545 1.00 33.24  ? 273 ASP C N   1 
ATOM   9649  C CA  . ASP C 1 273 ? 107.966 129.480 124.202 1.00 33.24  ? 273 ASP C CA  1 
ATOM   9650  C C   . ASP C 1 273 ? 106.944 129.784 125.291 1.00 33.24  ? 273 ASP C C   1 
ATOM   9651  O O   . ASP C 1 273 ? 105.797 129.333 125.190 1.00 33.24  ? 273 ASP C O   1 
ATOM   9652  C CB  . ASP C 1 273 ? 107.978 127.976 123.910 1.00 33.24  ? 273 ASP C CB  1 
ATOM   9653  C CG  . ASP C 1 273 ? 108.507 127.652 122.526 1.00 33.24  ? 273 ASP C CG  1 
ATOM   9654  O OD1 . ASP C 1 273 ? 108.163 128.370 121.565 1.00 33.24  ? 273 ASP C OD1 1 
ATOM   9655  O OD2 . ASP C 1 273 ? 109.272 126.675 122.399 1.00 33.24  ? 273 ASP C OD2 1 
ATOM   9656  N N   . ALA C 1 274 ? 107.322 130.530 126.325 1.00 32.89  ? 274 ALA C N   1 
ATOM   9657  C CA  . ALA C 1 274 ? 106.400 130.823 127.413 1.00 32.89  ? 274 ALA C CA  1 
ATOM   9658  C C   . ALA C 1 274 ? 105.346 131.837 126.969 1.00 32.89  ? 274 ALA C C   1 
ATOM   9659  O O   . ALA C 1 274 ? 105.658 132.778 126.236 1.00 32.89  ? 274 ALA C O   1 
ATOM   9660  C CB  . ALA C 1 274 ? 107.157 131.359 128.626 1.00 32.89  ? 274 ALA C CB  1 
ATOM   9661  N N   . PRO C 1 275 ? 104.097 131.674 127.396 1.00 34.13  ? 275 PRO C N   1 
ATOM   9662  C CA  . PRO C 1 275 ? 103.059 132.647 127.038 1.00 34.13  ? 275 PRO C CA  1 
ATOM   9663  C C   . PRO C 1 275 ? 103.224 133.962 127.786 1.00 34.13  ? 275 PRO C C   1 
ATOM   9664  O O   . PRO C 1 275 ? 103.868 134.046 128.832 1.00 34.13  ? 275 PRO C O   1 
ATOM   9665  C CB  . PRO C 1 275 ? 101.758 131.941 127.435 1.00 34.13  ? 275 PRO C CB  1 
ATOM   9666  C CG  . PRO C 1 275 ? 102.162 130.945 128.452 1.00 34.13  ? 275 PRO C CG  1 
ATOM   9667  C CD  . PRO C 1 275 ? 103.546 130.506 128.100 1.00 34.13  ? 275 PRO C CD  1 
ATOM   9668  N N   . ILE C 1 276 ? 102.614 135.003 127.226 1.00 35.73  ? 276 ILE C N   1 
ATOM   9669  C CA  . ILE C 1 276 ? 102.707 136.364 127.741 1.00 35.73  ? 276 ILE C CA  1 
ATOM   9670  C C   . ILE C 1 276 ? 101.380 136.725 128.394 1.00 35.73  ? 276 ILE C C   1 
ATOM   9671  O O   . ILE C 1 276 ? 100.316 136.557 127.786 1.00 35.73  ? 276 ILE C O   1 
ATOM   9672  C CB  . ILE C 1 276 ? 103.064 137.357 126.622 1.00 35.73  ? 276 ILE C CB  1 
ATOM   9673  C CG1 . ILE C 1 276 ? 104.388 136.956 125.968 1.00 35.73  ? 276 ILE C CG1 1 
ATOM   9674  C CG2 . ILE C 1 276 ? 103.125 138.779 127.160 1.00 35.73  ? 276 ILE C CG2 1 
ATOM   9675  C CD1 . ILE C 1 276 ? 104.779 137.816 124.797 1.00 35.73  ? 276 ILE C CD1 1 
ATOM   9676  N N   . GLU C 1 277 ? 101.441 137.220 129.629 1.00 41.19  ? 277 GLU C N   1 
ATOM   9677  C CA  . GLU C 1 277 ? 100.258 137.535 130.418 1.00 41.19  ? 277 GLU C CA  1 
ATOM   9678  C C   . GLU C 1 277 ? 100.377 138.936 131.001 1.00 41.19  ? 277 GLU C C   1 
ATOM   9679  O O   . GLU C 1 277 ? 101.447 139.549 130.998 1.00 41.19  ? 277 GLU C O   1 
ATOM   9680  C CB  . GLU C 1 277 ? 100.047 136.515 131.543 1.00 41.19  ? 277 GLU C CB  1 
ATOM   9681  C CG  . GLU C 1 277 ? 100.024 135.073 131.075 1.00 41.19  ? 277 GLU C CG  1 
ATOM   9682  C CD  . GLU C 1 277 ? 98.642  134.614 130.658 1.00 41.19  ? 277 GLU C CD  1 
ATOM   9683  O OE1 . GLU C 1 277 ? 97.769  134.480 131.540 1.00 41.19  ? 277 GLU C OE1 1 
ATOM   9684  O OE2 . GLU C 1 277 ? 98.430  134.384 129.448 1.00 41.19  ? 277 GLU C OE2 1 
ATOM   9685  N N   . THR C 1 278 ? 99.256  139.435 131.518 1.00 42.48  ? 278 THR C N   1 
ATOM   9686  C CA  . THR C 1 278 ? 99.174  140.777 132.094 1.00 42.48  ? 278 THR C CA  1 
ATOM   9687  C C   . THR C 1 278 ? 99.567  140.709 133.566 1.00 42.48  ? 278 THR C C   1 
ATOM   9688  O O   . THR C 1 278 ? 98.780  140.278 134.412 1.00 42.48  ? 278 THR C O   1 
ATOM   9689  C CB  . THR C 1 278 ? 97.771  141.348 131.925 1.00 42.48  ? 278 THR C CB  1 
ATOM   9690  O OG1 . THR C 1 278 ? 97.441  141.410 130.533 1.00 42.48  ? 278 THR C OG1 1 
ATOM   9691  C CG2 . THR C 1 278 ? 97.686  142.741 132.520 1.00 42.48  ? 278 THR C CG2 1 
ATOM   9692  N N   . CYS C 1 279 ? 100.787 141.139 133.873 1.00 42.85  ? 279 CYS C N   1 
ATOM   9693  C CA  . CYS C 1 279 ? 101.286 141.199 135.241 1.00 42.85  ? 279 CYS C CA  1 
ATOM   9694  C C   . CYS C 1 279 ? 102.497 142.125 135.256 1.00 42.85  ? 279 CYS C C   1 
ATOM   9695  O O   . CYS C 1 279 ? 102.863 142.712 134.235 1.00 42.85  ? 279 CYS C O   1 
ATOM   9696  C CB  . CYS C 1 279 ? 101.628 139.805 135.778 1.00 42.85  ? 279 CYS C CB  1 
ATOM   9697  S SG  . CYS C 1 279 ? 102.499 138.725 134.619 1.00 42.85  ? 279 CYS C SG  1 
ATOM   9698  N N   . ILE C 1 280 ? 103.119 142.255 136.426 1.00 40.27  ? 280 ILE C N   1 
ATOM   9699  C CA  . ILE C 1 280 ? 104.271 143.129 136.614 1.00 40.27  ? 280 ILE C CA  1 
ATOM   9700  C C   . ILE C 1 280 ? 105.434 142.302 137.138 1.00 40.27  ? 280 ILE C C   1 
ATOM   9701  O O   . ILE C 1 280 ? 105.285 141.556 138.113 1.00 40.27  ? 280 ILE C O   1 
ATOM   9702  C CB  . ILE C 1 280 ? 103.957 144.292 137.573 1.00 40.27  ? 280 ILE C CB  1 
ATOM   9703  C CG1 . ILE C 1 280 ? 102.735 145.071 137.085 1.00 40.27  ? 280 ILE C CG1 1 
ATOM   9704  C CG2 . ILE C 1 280 ? 105.160 145.214 137.700 1.00 40.27  ? 280 ILE C CG2 1 
ATOM   9705  C CD1 . ILE C 1 280 ? 102.514 146.371 137.814 1.00 40.27  ? 280 ILE C CD1 1 
ATOM   9706  N N   . SER C 1 281 ? 106.591 142.442 136.495 1.00 38.51  ? 281 SER C N   1 
ATOM   9707  C CA  . SER C 1 281 ? 107.803 141.751 136.907 1.00 38.51  ? 281 SER C CA  1 
ATOM   9708  C C   . SER C 1 281 ? 108.991 142.412 136.227 1.00 38.51  ? 281 SER C C   1 
ATOM   9709  O O   . SER C 1 281 ? 108.919 142.764 135.048 1.00 38.51  ? 281 SER C O   1 
ATOM   9710  C CB  . SER C 1 281 ? 107.748 140.260 136.558 1.00 38.51  ? 281 SER C CB  1 
ATOM   9711  O OG  . SER C 1 281 ? 108.751 139.536 137.246 1.00 38.51  ? 281 SER C OG  1 
ATOM   9712  N N   . GLU C 1 282 ? 110.078 142.576 136.975 1.00 38.10  ? 282 GLU C N   1 
ATOM   9713  C CA  . GLU C 1 282 ? 111.269 143.235 136.461 1.00 38.10  ? 282 GLU C CA  1 
ATOM   9714  C C   . GLU C 1 282 ? 112.282 142.278 135.844 1.00 38.10  ? 282 GLU C C   1 
ATOM   9715  O O   . GLU C 1 282 ? 113.192 142.741 135.150 1.00 38.10  ? 282 GLU C O   1 
ATOM   9716  C CB  . GLU C 1 282 ? 111.949 144.036 137.577 1.00 38.10  ? 282 GLU C CB  1 
ATOM   9717  C CG  . GLU C 1 282 ? 111.179 145.269 138.015 1.00 38.10  ? 282 GLU C CG  1 
ATOM   9718  C CD  . GLU C 1 282 ? 111.630 146.525 137.297 1.00 38.10  ? 282 GLU C CD  1 
ATOM   9719  O OE1 . GLU C 1 282 ? 112.426 146.415 136.341 1.00 38.10  ? 282 GLU C OE1 1 
ATOM   9720  O OE2 . GLU C 1 282 ? 111.188 147.626 137.689 1.00 38.10  ? 282 GLU C OE2 1 
ATOM   9721  N N   . CYS C 1 283 ? 112.157 140.969 136.066 1.00 34.02  ? 283 CYS C N   1 
ATOM   9722  C CA  . CYS C 1 283 ? 113.141 140.002 135.590 1.00 34.02  ? 283 CYS C CA  1 
ATOM   9723  C C   . CYS C 1 283 ? 112.463 138.930 134.750 1.00 34.02  ? 283 CYS C C   1 
ATOM   9724  O O   . CYS C 1 283 ? 111.557 138.238 135.230 1.00 34.02  ? 283 CYS C O   1 
ATOM   9725  C CB  . CYS C 1 283 ? 113.900 139.360 136.754 1.00 34.02  ? 283 CYS C CB  1 
ATOM   9726  S SG  . CYS C 1 283 ? 115.138 138.151 136.227 1.00 34.02  ? 283 CYS C SG  1 
ATOM   9727  N N   . ILE C 1 284 ? 112.951 138.761 133.519 1.00 30.07  ? 284 ILE C N   1 
ATOM   9728  C CA  . ILE C 1 284 ? 112.408 137.832 132.535 1.00 30.07  ? 284 ILE C CA  1 
ATOM   9729  C C   . ILE C 1 284 ? 113.484 136.819 132.168 1.00 30.07  ? 284 ILE C C   1 
ATOM   9730  O O   . ILE C 1 284 ? 114.639 137.190 131.932 1.00 30.07  ? 284 ILE C O   1 
ATOM   9731  C CB  . ILE C 1 284 ? 111.920 138.581 131.275 1.00 30.07  ? 284 ILE C CB  1 
ATOM   9732  C CG1 . ILE C 1 284 ? 110.784 139.544 131.624 1.00 30.07  ? 284 ILE C CG1 1 
ATOM   9733  C CG2 . ILE C 1 284 ? 111.490 137.606 130.187 1.00 30.07  ? 284 ILE C CG2 1 
ATOM   9734  C CD1 . ILE C 1 284 ? 110.526 140.586 130.562 1.00 30.07  ? 284 ILE C CD1 1 
ATOM   9735  N N   . THR C 1 285 ? 113.110 135.546 132.118 1.00 28.63  ? 285 THR C N   1 
ATOM   9736  C CA  . THR C 1 285 ? 113.953 134.452 131.661 1.00 28.63  ? 285 THR C CA  1 
ATOM   9737  C C   . THR C 1 285 ? 113.182 133.674 130.610 1.00 28.63  ? 285 THR C C   1 
ATOM   9738  O O   . THR C 1 285 ? 111.969 133.852 130.459 1.00 28.63  ? 285 THR C O   1 
ATOM   9739  C CB  . THR C 1 285 ? 114.352 133.523 132.826 1.00 28.63  ? 285 THR C CB  1 
ATOM   9740  O OG1 . THR C 1 285 ? 113.261 132.654 133.153 1.00 28.63  ? 285 THR C OG1 1 
ATOM   9741  C CG2 . THR C 1 285 ? 114.750 134.318 134.059 1.00 28.63  ? 285 THR C CG2 1 
ATOM   9742  N N   . PRO C 1 286 ? 113.855 132.804 129.850 1.00 28.51  ? 286 PRO C N   1 
ATOM   9743  C CA  . PRO C 1 286 ? 113.116 131.953 128.903 1.00 28.51  ? 286 PRO C CA  1 
ATOM   9744  C C   . PRO C 1 286 ? 112.089 131.051 129.566 1.00 28.51  ? 286 PRO C C   1 
ATOM   9745  O O   . PRO C 1 286 ? 111.170 130.586 128.883 1.00 28.51  ? 286 PRO C O   1 
ATOM   9746  C CB  . PRO C 1 286 ? 114.224 131.136 128.225 1.00 28.51  ? 286 PRO C CB  1 
ATOM   9747  C CG  . PRO C 1 286 ? 115.437 131.968 128.360 1.00 28.51  ? 286 PRO C CG  1 
ATOM   9748  C CD  . PRO C 1 286 ? 115.312 132.678 129.670 1.00 28.51  ? 286 PRO C CD  1 
ATOM   9749  N N   . ASN C 1 287 ? 112.212 130.784 130.867 1.00 31.19  ? 287 ASN C N   1 
ATOM   9750  C CA  . ASN C 1 287 ? 111.205 130.017 131.588 1.00 31.19  ? 287 ASN C CA  1 
ATOM   9751  C C   . ASN C 1 287 ? 110.010 130.856 132.020 1.00 31.19  ? 287 ASN C C   1 
ATOM   9752  O O   . ASN C 1 287 ? 108.991 130.285 132.418 1.00 31.19  ? 287 ASN C O   1 
ATOM   9753  C CB  . ASN C 1 287 ? 111.814 129.357 132.829 1.00 31.19  ? 287 ASN C CB  1 
ATOM   9754  C CG  . ASN C 1 287 ? 113.088 128.596 132.531 1.00 31.19  ? 287 ASN C CG  1 
ATOM   9755  O OD1 . ASN C 1 287 ? 114.064 129.161 132.046 1.00 31.19  ? 287 ASN C OD1 1 
ATOM   9756  N ND2 . ASN C 1 287 ? 113.084 127.302 132.828 1.00 31.19  ? 287 ASN C ND2 1 
ATOM   9757  N N   . GLY C 1 288 ? 110.106 132.182 131.961 1.00 30.65  ? 288 GLY C N   1 
ATOM   9758  C CA  . GLY C 1 288 ? 109.071 133.076 132.429 1.00 30.65  ? 288 GLY C CA  1 
ATOM   9759  C C   . GLY C 1 288 ? 109.650 134.150 133.320 1.00 30.65  ? 288 GLY C C   1 
ATOM   9760  O O   . GLY C 1 288 ? 110.867 134.300 133.450 1.00 30.65  ? 288 GLY C O   1 
ATOM   9761  N N   . SER C 1 289 ? 108.772 134.934 133.929 1.00 32.54  ? 289 SER C N   1 
ATOM   9762  C CA  . SER C 1 289 ? 109.215 135.974 134.843 1.00 32.54  ? 289 SER C CA  1 
ATOM   9763  C C   . SER C 1 289 ? 109.544 135.382 136.207 1.00 32.54  ? 289 SER C C   1 
ATOM   9764  O O   . SER C 1 289 ? 108.954 134.384 136.631 1.00 32.54  ? 289 SER C O   1 
ATOM   9765  C CB  . SER C 1 289 ? 108.144 137.052 134.986 1.00 32.54  ? 289 SER C CB  1 
ATOM   9766  O OG  . SER C 1 289 ? 107.977 137.761 133.774 1.00 32.54  ? 289 SER C OG  1 
ATOM   9767  N N   . ILE C 1 290 ? 110.500 136.000 136.894 1.00 32.68  ? 290 ILE C N   1 
ATOM   9768  C CA  . ILE C 1 290 ? 110.823 135.560 138.253 1.00 32.68  ? 290 ILE C CA  1 
ATOM   9769  C C   . ILE C 1 290 ? 110.913 136.757 139.193 1.00 32.68  ? 290 ILE C C   1 
ATOM   9770  O O   . ILE C 1 290 ? 111.350 137.840 138.780 1.00 32.68  ? 290 ILE C O   1 
ATOM   9771  C CB  . ILE C 1 290 ? 112.124 134.739 138.296 1.00 32.68  ? 290 ILE C CB  1 
ATOM   9772  C CG1 . ILE C 1 290 ? 113.301 135.543 137.747 1.00 32.68  ? 290 ILE C CG1 1 
ATOM   9773  C CG2 . ILE C 1 290 ? 111.969 133.418 137.551 1.00 32.68  ? 290 ILE C CG2 1 
ATOM   9774  C CD1 . ILE C 1 290 ? 114.643 134.905 138.013 1.00 32.68  ? 290 ILE C CD1 1 
ATOM   9775  N N   . PRO C 1 291 ? 110.504 136.612 140.453 1.00 34.11  ? 291 PRO C N   1 
ATOM   9776  C CA  . PRO C 1 291 ? 110.725 137.684 141.430 1.00 34.11  ? 291 PRO C CA  1 
ATOM   9777  C C   . PRO C 1 291 ? 112.206 137.861 141.727 1.00 34.11  ? 291 PRO C C   1 
ATOM   9778  O O   . PRO C 1 291 ? 113.000 136.923 141.629 1.00 34.11  ? 291 PRO C O   1 
ATOM   9779  C CB  . PRO C 1 291 ? 109.959 137.204 142.668 1.00 34.11  ? 291 PRO C CB  1 
ATOM   9780  C CG  . PRO C 1 291 ? 109.846 135.735 142.505 1.00 34.11  ? 291 PRO C CG  1 
ATOM   9781  C CD  . PRO C 1 291 ? 109.784 135.467 141.035 1.00 34.11  ? 291 PRO C CD  1 
ATOM   9782  N N   . ASN C 1 292 ? 112.577 139.086 142.095 1.00 36.24  ? 292 ASN C N   1 
ATOM   9783  C CA  . ASN C 1 292 ? 113.981 139.433 142.284 1.00 36.24  ? 292 ASN C CA  1 
ATOM   9784  C C   . ASN C 1 292 ? 114.293 139.875 143.713 1.00 36.24  ? 292 ASN C C   1 
ATOM   9785  O O   . ASN C 1 292 ? 115.239 140.632 143.935 1.00 36.24  ? 292 ASN C O   1 
ATOM   9786  C CB  . ASN C 1 292 ? 114.409 140.512 141.289 1.00 36.24  ? 292 ASN C CB  1 
ATOM   9787  C CG  . ASN C 1 292 ? 113.640 141.810 141.455 1.00 36.24  ? 292 ASN C CG  1 
ATOM   9788  O OD1 . ASN C 1 292 ? 112.719 141.906 142.262 1.00 36.24  ? 292 ASN C OD1 1 
ATOM   9789  N ND2 . ASN C 1 292 ? 114.028 142.823 140.694 1.00 36.24  ? 292 ASN C ND2 1 
ATOM   9790  N N   . ASP C 1 293 ? 113.523 139.410 144.697 1.00 36.87  ? 293 ASP C N   1 
ATOM   9791  C CA  . ASP C 1 293 ? 113.822 139.766 146.080 1.00 36.87  ? 293 ASP C CA  1 
ATOM   9792  C C   . ASP C 1 293 ? 114.992 138.976 146.657 1.00 36.87  ? 293 ASP C C   1 
ATOM   9793  O O   . ASP C 1 293 ? 115.568 139.400 147.663 1.00 36.87  ? 293 ASP C O   1 
ATOM   9794  C CB  . ASP C 1 293 ? 112.586 139.584 146.966 1.00 36.87  ? 293 ASP C CB  1 
ATOM   9795  C CG  . ASP C 1 293 ? 111.799 138.337 146.628 1.00 36.87  ? 293 ASP C CG  1 
ATOM   9796  O OD1 . ASP C 1 293 ? 112.270 137.225 146.941 1.00 36.87  ? 293 ASP C OD1 1 
ATOM   9797  O OD2 . ASP C 1 293 ? 110.699 138.470 146.055 1.00 36.87  ? 293 ASP C OD2 1 
ATOM   9798  N N   . LYS C 1 294 ? 115.360 137.860 146.048 1.00 32.60  ? 294 LYS C N   1 
ATOM   9799  C CA  . LYS C 1 294 ? 116.498 137.081 146.505 1.00 32.60  ? 294 LYS C CA  1 
ATOM   9800  C C   . LYS C 1 294 ? 117.750 137.437 145.711 1.00 32.60  ? 294 LYS C C   1 
ATOM   9801  O O   . LYS C 1 294 ? 117.660 137.856 144.555 1.00 32.60  ? 294 LYS C O   1 
ATOM   9802  C CB  . LYS C 1 294 ? 116.210 135.583 146.372 1.00 32.60  ? 294 LYS C CB  1 
ATOM   9803  C CG  . LYS C 1 294 ? 115.200 135.071 147.383 1.00 32.60  ? 294 LYS C CG  1 
ATOM   9804  C CD  . LYS C 1 294 ? 114.765 133.651 147.081 1.00 32.60  ? 294 LYS C CD  1 
ATOM   9805  C CE  . LYS C 1 294 ? 113.433 133.340 147.739 1.00 32.60  ? 294 LYS C CE  1 
ATOM   9806  N NZ  . LYS C 1 294 ? 113.214 131.879 147.900 1.00 32.60  ? 294 LYS C NZ  1 
ATOM   9807  N N   . PRO C 1 295 ? 118.939 137.288 146.306 1.00 29.45  ? 295 PRO C N   1 
ATOM   9808  C CA  . PRO C 1 295 ? 120.169 137.670 145.592 1.00 29.45  ? 295 PRO C CA  1 
ATOM   9809  C C   . PRO C 1 295 ? 120.646 136.666 144.551 1.00 29.45  ? 295 PRO C C   1 
ATOM   9810  O O   . PRO C 1 295 ? 121.467 137.036 143.702 1.00 29.45  ? 295 PRO C O   1 
ATOM   9811  C CB  . PRO C 1 295 ? 121.197 137.809 146.723 1.00 29.45  ? 295 PRO C CB  1 
ATOM   9812  C CG  . PRO C 1 295 ? 120.698 136.905 147.789 1.00 29.45  ? 295 PRO C CG  1 
ATOM   9813  C CD  . PRO C 1 295 ? 119.200 136.955 147.717 1.00 29.45  ? 295 PRO C CD  1 
ATOM   9814  N N   . PHE C 1 296 ? 120.172 135.421 144.579 1.00 27.93  ? 296 PHE C N   1 
ATOM   9815  C CA  . PHE C 1 296 ? 120.646 134.389 143.669 1.00 27.93  ? 296 PHE C CA  1 
ATOM   9816  C C   . PHE C 1 296 ? 119.467 133.644 143.061 1.00 27.93  ? 296 PHE C C   1 
ATOM   9817  O O   . PHE C 1 296 ? 118.383 133.582 143.646 1.00 27.93  ? 296 PHE C O   1 
ATOM   9818  C CB  . PHE C 1 296 ? 121.574 133.392 144.381 1.00 27.93  ? 296 PHE C CB  1 
ATOM   9819  C CG  . PHE C 1 296 ? 122.722 134.036 145.105 1.00 27.93  ? 296 PHE C CG  1 
ATOM   9820  C CD1 . PHE C 1 296 ? 123.684 134.748 144.413 1.00 27.93  ? 296 PHE C CD1 1 
ATOM   9821  C CD2 . PHE C 1 296 ? 122.842 133.924 146.479 1.00 27.93  ? 296 PHE C CD2 1 
ATOM   9822  C CE1 . PHE C 1 296 ? 124.738 135.338 145.075 1.00 27.93  ? 296 PHE C CE1 1 
ATOM   9823  C CE2 . PHE C 1 296 ? 123.897 134.513 147.146 1.00 27.93  ? 296 PHE C CE2 1 
ATOM   9824  C CZ  . PHE C 1 296 ? 124.845 135.221 146.444 1.00 27.93  ? 296 PHE C CZ  1 
ATOM   9825  N N   . GLN C 1 297 ? 119.691 133.073 141.879 1.00 26.02  ? 297 GLN C N   1 
ATOM   9826  C CA  . GLN C 1 297 ? 118.669 132.299 141.191 1.00 26.02  ? 297 GLN C CA  1 
ATOM   9827  C C   . GLN C 1 297 ? 119.309 131.100 140.505 1.00 26.02  ? 297 GLN C C   1 
ATOM   9828  O O   . GLN C 1 297 ? 120.502 131.091 140.199 1.00 26.02  ? 297 GLN C O   1 
ATOM   9829  C CB  . GLN C 1 297 ? 117.893 133.150 140.172 1.00 26.02  ? 297 GLN C CB  1 
ATOM   9830  C CG  . GLN C 1 297 ? 118.755 133.877 139.152 1.00 26.02  ? 297 GLN C CG  1 
ATOM   9831  C CD  . GLN C 1 297 ? 118.775 133.187 137.800 1.00 26.02  ? 297 GLN C CD  1 
ATOM   9832  O OE1 . GLN C 1 297 ? 118.150 132.147 137.615 1.00 26.02  ? 297 GLN C OE1 1 
ATOM   9833  N NE2 . GLN C 1 297 ? 119.495 133.766 136.850 1.00 26.02  ? 297 GLN C NE2 1 
ATOM   9834  N N   . ASN C 1 298 ? 118.484 130.082 140.270 1.00 27.00  ? 298 ASN C N   1 
ATOM   9835  C CA  . ASN C 1 298 ? 118.916 128.829 139.668 1.00 27.00  ? 298 ASN C CA  1 
ATOM   9836  C C   . ASN C 1 298 ? 118.071 128.460 138.453 1.00 27.00  ? 298 ASN C C   1 
ATOM   9837  O O   . ASN C 1 298 ? 118.150 127.323 137.976 1.00 27.00  ? 298 ASN C O   1 
ATOM   9838  C CB  . ASN C 1 298 ? 118.862 127.708 140.715 1.00 27.00  ? 298 ASN C CB  1 
ATOM   9839  C CG  . ASN C 1 298 ? 119.661 126.492 140.317 1.00 27.00  ? 298 ASN C CG  1 
ATOM   9840  O OD1 . ASN C 1 298 ? 120.746 126.603 139.752 1.00 27.00  ? 298 ASN C OD1 1 
ATOM   9841  N ND2 . ASN C 1 298 ? 119.124 125.316 140.611 1.00 27.00  ? 298 ASN C ND2 1 
ATOM   9842  N N   . VAL C 1 299 ? 117.275 129.393 137.933 1.00 27.32  ? 299 VAL C N   1 
ATOM   9843  C CA  . VAL C 1 299 ? 116.302 129.059 136.899 1.00 27.32  ? 299 VAL C CA  1 
ATOM   9844  C C   . VAL C 1 299 ? 116.958 128.998 135.524 1.00 27.32  ? 299 VAL C C   1 
ATOM   9845  O O   . VAL C 1 299 ? 116.813 128.009 134.798 1.00 27.32  ? 299 VAL C O   1 
ATOM   9846  C CB  . VAL C 1 299 ? 115.136 130.065 136.929 1.00 27.32  ? 299 VAL C CB  1 
ATOM   9847  C CG1 . VAL C 1 299 ? 114.140 129.766 135.824 1.00 27.32  ? 299 VAL C CG1 1 
ATOM   9848  C CG2 . VAL C 1 299 ? 114.453 130.042 138.288 1.00 27.32  ? 299 VAL C CG2 1 
ATOM   9849  N N   . ASN C 1 300 ? 117.688 130.044 135.143 1.00 26.26  ? 300 ASN C N   1 
ATOM   9850  C CA  . ASN C 1 300 ? 118.254 130.124 133.803 1.00 26.26  ? 300 ASN C CA  1 
ATOM   9851  C C   . ASN C 1 300 ? 119.356 131.172 133.782 1.00 26.26  ? 300 ASN C C   1 
ATOM   9852  O O   . ASN C 1 300 ? 119.198 132.252 134.352 1.00 26.26  ? 300 ASN C O   1 
ATOM   9853  C CB  . ASN C 1 300 ? 117.178 130.479 132.768 1.00 26.26  ? 300 ASN C CB  1 
ATOM   9854  C CG  . ASN C 1 300 ? 117.487 129.934 131.391 1.00 26.26  ? 300 ASN C CG  1 
ATOM   9855  O OD1 . ASN C 1 300 ? 118.559 130.172 130.842 1.00 26.26  ? 300 ASN C OD1 1 
ATOM   9856  N ND2 . ASN C 1 300 ? 116.543 129.200 130.823 1.00 26.26  ? 300 ASN C ND2 1 
ATOM   9857  N N   . LYS C 1 301 ? 120.460 130.854 133.105 1.00 26.95  ? 301 LYS C N   1 
ATOM   9858  C CA  . LYS C 1 301 ? 121.549 131.809 132.947 1.00 26.95  ? 301 LYS C CA  1 
ATOM   9859  C C   . LYS C 1 301 ? 121.261 132.875 131.895 1.00 26.95  ? 301 LYS C C   1 
ATOM   9860  O O   . LYS C 1 301 ? 122.032 133.833 131.786 1.00 26.95  ? 301 LYS C O   1 
ATOM   9861  C CB  . LYS C 1 301 ? 122.851 131.078 132.607 1.00 26.95  ? 301 LYS C CB  1 
ATOM   9862  C CG  . LYS C 1 301 ? 122.842 130.328 131.291 1.00 26.95  ? 301 LYS C CG  1 
ATOM   9863  C CD  . LYS C 1 301 ? 124.053 129.417 131.182 1.00 26.95  ? 301 LYS C CD  1 
ATOM   9864  C CE  . LYS C 1 301 ? 124.143 128.773 129.808 1.00 26.95  ? 301 LYS C CE  1 
ATOM   9865  N NZ  . LYS C 1 301 ? 123.620 127.380 129.801 1.00 26.95  ? 301 LYS C NZ  1 
ATOM   9866  N N   . ILE C 1 302 ? 120.185 132.738 131.128 1.00 26.35  ? 302 ILE C N   1 
ATOM   9867  C CA  . ILE C 1 302 ? 119.750 133.772 130.196 1.00 26.35  ? 302 ILE C CA  1 
ATOM   9868  C C   . ILE C 1 302 ? 118.715 134.639 130.901 1.00 26.35  ? 302 ILE C C   1 
ATOM   9869  O O   . ILE C 1 302 ? 117.670 134.142 131.331 1.00 26.35  ? 302 ILE C O   1 
ATOM   9870  C CB  . ILE C 1 302 ? 119.174 133.155 128.911 1.00 26.35  ? 302 ILE C CB  1 
ATOM   9871  C CG1 . ILE C 1 302 ? 120.280 132.468 128.110 1.00 26.35  ? 302 ILE C CG1 1 
ATOM   9872  C CG2 . ILE C 1 302 ? 118.474 134.212 128.074 1.00 26.35  ? 302 ILE C CG2 1 
ATOM   9873  C CD1 . ILE C 1 302 ? 119.797 131.322 127.258 1.00 26.35  ? 302 ILE C CD1 1 
ATOM   9874  N N   . THR C 1 303 ? 118.999 135.935 131.023 1.00 28.80  ? 303 THR C N   1 
ATOM   9875  C CA  . THR C 1 303 ? 118.132 136.842 131.763 1.00 28.80  ? 303 THR C CA  1 
ATOM   9876  C C   . THR C 1 303 ? 118.068 138.191 131.062 1.00 28.80  ? 303 THR C C   1 
ATOM   9877  O O   . THR C 1 303 ? 118.945 138.550 130.274 1.00 28.80  ? 303 THR C O   1 
ATOM   9878  C CB  . THR C 1 303 ? 118.607 137.046 133.217 1.00 28.80  ? 303 THR C CB  1 
ATOM   9879  O OG1 . THR C 1 303 ? 120.010 137.337 133.236 1.00 28.80  ? 303 THR C OG1 1 
ATOM   9880  C CG2 . THR C 1 303 ? 118.335 135.811 134.065 1.00 28.80  ? 303 THR C CG2 1 
ATOM   9881  N N   . TYR C 1 304 ? 117.006 138.936 131.365 1.00 29.72  ? 304 TYR C N   1 
ATOM   9882  C CA  . TYR C 1 304 ? 116.839 140.310 130.909 1.00 29.72  ? 304 TYR C CA  1 
ATOM   9883  C C   . TYR C 1 304 ? 116.212 141.125 132.029 1.00 29.72  ? 304 TYR C C   1 
ATOM   9884  O O   . TYR C 1 304 ? 115.198 140.716 132.600 1.00 29.72  ? 304 TYR C O   1 
ATOM   9885  C CB  . TYR C 1 304 ? 115.967 140.383 129.649 1.00 29.72  ? 304 TYR C CB  1 
ATOM   9886  C CG  . TYR C 1 304 ? 115.773 141.787 129.118 1.00 29.72  ? 304 TYR C CG  1 
ATOM   9887  C CD1 . TYR C 1 304 ? 116.698 142.356 128.256 1.00 29.72  ? 304 TYR C CD1 1 
ATOM   9888  C CD2 . TYR C 1 304 ? 114.668 142.544 129.482 1.00 29.72  ? 304 TYR C CD2 1 
ATOM   9889  C CE1 . TYR C 1 304 ? 116.530 143.636 127.769 1.00 29.72  ? 304 TYR C CE1 1 
ATOM   9890  C CE2 . TYR C 1 304 ? 114.493 143.827 129.005 1.00 29.72  ? 304 TYR C CE2 1 
ATOM   9891  C CZ  . TYR C 1 304 ? 115.427 144.368 128.147 1.00 29.72  ? 304 TYR C CZ  1 
ATOM   9892  O OH  . TYR C 1 304 ? 115.261 145.643 127.663 1.00 29.72  ? 304 TYR C OH  1 
ATOM   9893  N N   . GLY C 1 305 ? 116.806 142.270 132.336 1.00 33.29  ? 305 GLY C N   1 
ATOM   9894  C CA  . GLY C 1 305 ? 116.290 143.177 133.340 1.00 33.29  ? 305 GLY C CA  1 
ATOM   9895  C C   . GLY C 1 305 ? 117.081 143.141 134.634 1.00 33.29  ? 305 GLY C C   1 
ATOM   9896  O O   . GLY C 1 305 ? 118.265 142.800 134.672 1.00 33.29  ? 305 GLY C O   1 
ATOM   9897  N N   . ALA C 1 306 ? 116.400 143.512 135.718 1.00 35.39  ? 306 ALA C N   1 
ATOM   9898  C CA  . ALA C 1 306 ? 116.982 143.510 137.062 1.00 35.39  ? 306 ALA C CA  1 
ATOM   9899  C C   . ALA C 1 306 ? 116.792 142.123 137.663 1.00 35.39  ? 306 ALA C C   1 
ATOM   9900  O O   . ALA C 1 306 ? 115.699 141.770 138.106 1.00 35.39  ? 306 ALA C O   1 
ATOM   9901  C CB  . ALA C 1 306 ? 116.337 144.584 137.930 1.00 35.39  ? 306 ALA C CB  1 
ATOM   9902  N N   . CYS C 1 307 ? 117.863 141.338 137.692 1.00 33.40  ? 307 CYS C N   1 
ATOM   9903  C CA  . CYS C 1 307 ? 117.756 139.921 137.990 1.00 33.40  ? 307 CYS C CA  1 
ATOM   9904  C C   . CYS C 1 307 ? 118.768 139.500 139.044 1.00 33.40  ? 307 CYS C C   1 
ATOM   9905  O O   . CYS C 1 307 ? 119.823 140.124 139.187 1.00 33.40  ? 307 CYS C O   1 
ATOM   9906  C CB  . CYS C 1 307 ? 117.970 139.088 136.718 1.00 33.40  ? 307 CYS C CB  1 
ATOM   9907  S SG  . CYS C 1 307 ? 116.661 139.270 135.485 1.00 33.40  ? 307 CYS C SG  1 
ATOM   9908  N N   . PRO C 1 308 ? 118.465 138.449 139.802 1.00 29.82  ? 308 PRO C N   1 
ATOM   9909  C CA  . PRO C 1 308 ? 119.477 137.858 140.682 1.00 29.82  ? 308 PRO C CA  1 
ATOM   9910  C C   . PRO C 1 308 ? 120.564 137.165 139.876 1.00 29.82  ? 308 PRO C C   1 
ATOM   9911  O O   . PRO C 1 308 ? 120.381 136.794 138.716 1.00 29.82  ? 308 PRO C O   1 
ATOM   9912  C CB  . PRO C 1 308 ? 118.684 136.850 141.523 1.00 29.82  ? 308 PRO C CB  1 
ATOM   9913  C CG  . PRO C 1 308 ? 117.241 137.170 141.285 1.00 29.82  ? 308 PRO C CG  1 
ATOM   9914  C CD  . PRO C 1 308 ? 117.161 137.783 139.934 1.00 29.82  ? 308 PRO C CD  1 
ATOM   9915  N N   . LYS C 1 309 ? 121.719 137.001 140.512 1.00 28.80  ? 309 LYS C N   1 
ATOM   9916  C CA  . LYS C 1 309 ? 122.850 136.349 139.871 1.00 28.80  ? 309 LYS C CA  1 
ATOM   9917  C C   . LYS C 1 309 ? 122.630 134.844 139.791 1.00 28.80  ? 309 LYS C C   1 
ATOM   9918  O O   . LYS C 1 309 ? 122.133 134.223 140.733 1.00 28.80  ? 309 LYS C O   1 
ATOM   9919  C CB  . LYS C 1 309 ? 124.138 136.652 140.633 1.00 28.80  ? 309 LYS C CB  1 
ATOM   9920  C CG  . LYS C 1 309 ? 124.435 138.131 140.770 1.00 28.80  ? 309 LYS C CG  1 
ATOM   9921  C CD  . LYS C 1 309 ? 125.798 138.367 141.387 1.00 28.80  ? 309 LYS C CD  1 
ATOM   9922  C CE  . LYS C 1 309 ? 126.068 139.848 141.572 1.00 28.80  ? 309 LYS C CE  1 
ATOM   9923  N NZ  . LYS C 1 309 ? 125.214 140.438 142.638 1.00 28.80  ? 309 LYS C NZ  1 
ATOM   9924  N N   . TYR C 1 310 ? 123.007 134.259 138.659 1.00 25.23  ? 310 TYR C N   1 
ATOM   9925  C CA  . TYR C 1 310 ? 122.846 132.828 138.454 1.00 25.23  ? 310 TYR C CA  1 
ATOM   9926  C C   . TYR C 1 310 ? 123.930 132.050 139.190 1.00 25.23  ? 310 TYR C C   1 
ATOM   9927  O O   . TYR C 1 310 ? 125.109 132.405 139.144 1.00 25.23  ? 310 TYR C O   1 
ATOM   9928  C CB  . TYR C 1 310 ? 122.883 132.495 136.962 1.00 25.23  ? 310 TYR C CB  1 
ATOM   9929  C CG  . TYR C 1 310 ? 122.723 131.023 136.664 1.00 25.23  ? 310 TYR C CG  1 
ATOM   9930  C CD1 . TYR C 1 310 ? 121.470 130.428 136.664 1.00 25.23  ? 310 TYR C CD1 1 
ATOM   9931  C CD2 . TYR C 1 310 ? 123.825 130.227 136.392 1.00 25.23  ? 310 TYR C CD2 1 
ATOM   9932  C CE1 . TYR C 1 310 ? 121.320 129.084 136.396 1.00 25.23  ? 310 TYR C CE1 1 
ATOM   9933  C CE2 . TYR C 1 310 ? 123.685 128.883 136.126 1.00 25.23  ? 310 TYR C CE2 1 
ATOM   9934  C CZ  . TYR C 1 310 ? 122.431 128.317 136.127 1.00 25.23  ? 310 TYR C CZ  1 
ATOM   9935  O OH  . TYR C 1 310 ? 122.293 126.977 135.864 1.00 25.23  ? 310 TYR C OH  1 
ATOM   9936  N N   . VAL C 1 311 ? 123.520 130.983 139.877 1.00 25.05  ? 311 VAL C N   1 
ATOM   9937  C CA  . VAL C 1 311 ? 124.432 130.084 140.573 1.00 25.05  ? 311 VAL C CA  1 
ATOM   9938  C C   . VAL C 1 311 ? 124.022 128.649 140.270 1.00 25.05  ? 311 VAL C C   1 
ATOM   9939  O O   . VAL C 1 311 ? 122.936 128.383 139.756 1.00 25.05  ? 311 VAL C O   1 
ATOM   9940  C CB  . VAL C 1 311 ? 124.463 130.325 142.101 1.00 25.05  ? 311 VAL C CB  1 
ATOM   9941  C CG1 . VAL C 1 311 ? 125.050 131.689 142.420 1.00 25.05  ? 311 VAL C CG1 1 
ATOM   9942  C CG2 . VAL C 1 311 ? 123.073 130.175 142.706 1.00 25.05  ? 311 VAL C CG2 1 
ATOM   9943  N N   . LYS C 1 312 ? 124.915 127.718 140.596 1.00 28.40  ? 312 LYS C N   1 
ATOM   9944  C CA  . LYS C 1 312 ? 124.664 126.301 140.375 1.00 28.40  ? 312 LYS C CA  1 
ATOM   9945  C C   . LYS C 1 312 ? 123.884 125.637 141.504 1.00 28.40  ? 312 LYS C C   1 
ATOM   9946  O O   . LYS C 1 312 ? 123.222 124.623 141.261 1.00 28.40  ? 312 LYS C O   1 
ATOM   9947  C CB  . LYS C 1 312 ? 125.988 125.557 140.177 1.00 28.40  ? 312 LYS C CB  1 
ATOM   9948  C CG  . LYS C 1 312 ? 126.399 125.409 138.727 1.00 28.40  ? 312 LYS C CG  1 
ATOM   9949  C CD  . LYS C 1 312 ? 127.883 125.653 138.539 1.00 28.40  ? 312 LYS C CD  1 
ATOM   9950  C CE  . LYS C 1 312 ? 128.714 124.771 139.447 1.00 28.40  ? 312 LYS C CE  1 
ATOM   9951  N NZ  . LYS C 1 312 ? 130.031 125.386 139.756 1.00 28.40  ? 312 LYS C NZ  1 
ATOM   9952  N N   . GLN C 1 313 ? 123.946 126.171 142.720 1.00 29.02  ? 313 GLN C N   1 
ATOM   9953  C CA  . GLN C 1 313 ? 123.266 125.552 143.850 1.00 29.02  ? 313 GLN C CA  1 
ATOM   9954  C C   . GLN C 1 313 ? 121.760 125.781 143.776 1.00 29.02  ? 313 GLN C C   1 
ATOM   9955  O O   . GLN C 1 313 ? 121.288 126.828 143.330 1.00 29.02  ? 313 GLN C O   1 
ATOM   9956  C CB  . GLN C 1 313 ? 123.808 126.105 145.169 1.00 29.02  ? 313 GLN C CB  1 
ATOM   9957  C CG  . GLN C 1 313 ? 125.305 125.928 145.351 1.00 29.02  ? 313 GLN C CG  1 
ATOM   9958  C CD  . GLN C 1 313 ? 126.098 127.144 144.911 1.00 29.02  ? 313 GLN C CD  1 
ATOM   9959  O OE1 . GLN C 1 313 ? 125.804 127.752 143.885 1.00 29.02  ? 313 GLN C OE1 1 
ATOM   9960  N NE2 . GLN C 1 313 ? 127.112 127.499 145.686 1.00 29.02  ? 313 GLN C NE2 1 
ATOM   9961  N N   . ASN C 1 314 ? 121.000 124.784 144.228 1.00 33.35  ? 314 ASN C N   1 
ATOM   9962  C CA  . ASN C 1 314 ? 119.550 124.904 144.262 1.00 33.35  ? 314 ASN C CA  1 
ATOM   9963  C C   . ASN C 1 314 ? 119.012 125.380 145.607 1.00 33.35  ? 314 ASN C C   1 
ATOM   9964  O O   . ASN C 1 314 ? 117.820 125.687 145.699 1.00 33.35  ? 314 ASN C O   1 
ATOM   9965  C CB  . ASN C 1 314 ? 118.890 123.570 143.877 1.00 33.35  ? 314 ASN C CB  1 
ATOM   9966  C CG  . ASN C 1 314 ? 119.188 122.455 144.860 1.00 33.35  ? 314 ASN C CG  1 
ATOM   9967  O OD1 . ASN C 1 314 ? 118.620 122.400 145.949 1.00 33.35  ? 314 ASN C OD1 1 
ATOM   9968  N ND2 . ASN C 1 314 ? 120.076 121.550 144.472 1.00 33.35  ? 314 ASN C ND2 1 
ATOM   9969  N N   . THR C 1 315 ? 119.851 125.468 146.639 1.00 33.25  ? 315 THR C N   1 
ATOM   9970  C CA  . THR C 1 315 ? 119.407 125.982 147.929 1.00 33.25  ? 315 THR C CA  1 
ATOM   9971  C C   . THR C 1 315 ? 120.603 126.496 148.722 1.00 33.25  ? 315 THR C C   1 
ATOM   9972  O O   . THR C 1 315 ? 121.679 125.897 148.694 1.00 33.25  ? 315 THR C O   1 
ATOM   9973  C CB  . THR C 1 315 ? 118.652 124.913 148.736 1.00 33.25  ? 315 THR C CB  1 
ATOM   9974  O OG1 . THR C 1 315 ? 118.306 125.436 150.024 1.00 33.25  ? 315 THR C OG1 1 
ATOM   9975  C CG2 . THR C 1 315 ? 119.495 123.656 148.909 1.00 33.25  ? 315 THR C CG2 1 
ATOM   9976  N N   . LEU C 1 316 ? 120.399 127.613 149.418 1.00 32.79  ? 316 LEU C N   1 
ATOM   9977  C CA  . LEU C 1 316 ? 121.391 128.174 150.332 1.00 32.79  ? 316 LEU C CA  1 
ATOM   9978  C C   . LEU C 1 316 ? 120.642 128.837 151.477 1.00 32.79  ? 316 LEU C C   1 
ATOM   9979  O O   . LEU C 1 316 ? 119.851 129.755 151.246 1.00 32.79  ? 316 LEU C O   1 
ATOM   9980  C CB  . LEU C 1 316 ? 122.301 129.185 149.626 1.00 32.79  ? 316 LEU C CB  1 
ATOM   9981  C CG  . LEU C 1 316 ? 123.396 128.664 148.692 1.00 32.79  ? 316 LEU C CG  1 
ATOM   9982  C CD1 . LEU C 1 316 ? 123.973 129.800 147.868 1.00 32.79  ? 316 LEU C CD1 1 
ATOM   9983  C CD2 . LEU C 1 316 ? 124.493 127.964 149.473 1.00 32.79  ? 316 LEU C CD2 1 
ATOM   9984  N N   . LYS C 1 317 ? 120.887 128.382 152.701 1.00 35.67  ? 317 LYS C N   1 
ATOM   9985  C CA  . LYS C 1 317 ? 120.153 128.841 153.873 1.00 35.67  ? 317 LYS C CA  1 
ATOM   9986  C C   . LYS C 1 317 ? 121.015 129.784 154.700 1.00 35.67  ? 317 LYS C C   1 
ATOM   9987  O O   . LYS C 1 317 ? 122.127 129.424 155.099 1.00 35.67  ? 317 LYS C O   1 
ATOM   9988  C CB  . LYS C 1 317 ? 119.701 127.656 154.727 1.00 35.67  ? 317 LYS C CB  1 
ATOM   9989  C CG  . LYS C 1 317 ? 118.831 126.657 153.989 1.00 35.67  ? 317 LYS C CG  1 
ATOM   9990  C CD  . LYS C 1 317 ? 117.526 127.291 153.544 1.00 35.67  ? 317 LYS C CD  1 
ATOM   9991  C CE  . LYS C 1 317 ? 116.449 127.137 154.600 1.00 35.67  ? 317 LYS C CE  1 
ATOM   9992  N NZ  . LYS C 1 317 ? 115.595 128.350 154.698 1.00 35.67  ? 317 LYS C NZ  1 
ATOM   9993  N N   . LEU C 1 318 ? 120.496 130.978 154.969 1.00 36.24  ? 318 LEU C N   1 
ATOM   9994  C CA  . LEU C 1 318 ? 121.167 131.972 155.796 1.00 36.24  ? 318 LEU C CA  1 
ATOM   9995  C C   . LEU C 1 318 ? 120.493 132.040 157.160 1.00 36.24  ? 318 LEU C C   1 
ATOM   9996  O O   . LEU C 1 318 ? 119.275 132.223 157.246 1.00 36.24  ? 318 LEU C O   1 
ATOM   9997  C CB  . LEU C 1 318 ? 121.145 133.348 155.128 1.00 36.24  ? 318 LEU C CB  1 
ATOM   9998  C CG  . LEU C 1 318 ? 121.888 134.465 155.864 1.00 36.24  ? 318 LEU C CG  1 
ATOM   9999  C CD1 . LEU C 1 318 ? 123.371 134.441 155.537 1.00 36.24  ? 318 LEU C CD1 1 
ATOM   10000 C CD2 . LEU C 1 318 ? 121.289 135.818 155.544 1.00 36.24  ? 318 LEU C CD2 1 
ATOM   10001 N N   . ALA C 1 319 ? 121.288 131.895 158.218 1.00 40.66  ? 319 ALA C N   1 
ATOM   10002 C CA  . ALA C 1 319 ? 120.753 131.897 159.573 1.00 40.66  ? 319 ALA C CA  1 
ATOM   10003 C C   . ALA C 1 319 ? 120.236 133.276 159.960 1.00 40.66  ? 319 ALA C C   1 
ATOM   10004 O O   . ALA C 1 319 ? 120.851 134.300 159.655 1.00 40.66  ? 319 ALA C O   1 
ATOM   10005 C CB  . ALA C 1 319 ? 121.820 131.446 160.568 1.00 40.66  ? 319 ALA C CB  1 
ATOM   10006 N N   . THR C 1 320 ? 119.098 133.294 160.651 1.00 47.77  ? 320 THR C N   1 
ATOM   10007 C CA  . THR C 1 320 ? 118.486 134.523 161.127 1.00 47.77  ? 320 THR C CA  1 
ATOM   10008 C C   . THR C 1 320 ? 118.377 134.591 162.648 1.00 47.77  ? 320 THR C C   1 
ATOM   10009 O O   . THR C 1 320 ? 118.361 135.697 163.200 1.00 47.77  ? 320 THR C O   1 
ATOM   10010 C CB  . THR C 1 320 ? 117.098 134.695 160.478 1.00 47.77  ? 320 THR C CB  1 
ATOM   10011 O OG1 . THR C 1 320 ? 117.266 135.119 159.120 1.00 47.77  ? 320 THR C OG1 1 
ATOM   10012 C CG2 . THR C 1 320 ? 116.241 135.722 161.197 1.00 47.77  ? 320 THR C CG2 1 
ATOM   10013 N N   . GLY C 1 321 ? 118.376 133.456 163.341 1.00 51.08  ? 321 GLY C N   1 
ATOM   10014 C CA  . GLY C 1 321 ? 118.367 133.455 164.791 1.00 51.08  ? 321 GLY C CA  1 
ATOM   10015 C C   . GLY C 1 321 ? 119.581 132.786 165.404 1.00 51.08  ? 321 GLY C C   1 
ATOM   10016 O O   . GLY C 1 321 ? 120.534 132.448 164.697 1.00 51.08  ? 321 GLY C O   1 
ATOM   10017 N N   . MET C 1 322 ? 119.560 132.591 166.720 1.00 55.84  ? 322 MET C N   1 
ATOM   10018 C CA  . MET C 1 322 ? 120.662 131.964 167.433 1.00 55.84  ? 322 MET C CA  1 
ATOM   10019 C C   . MET C 1 322 ? 120.560 130.443 167.335 1.00 55.84  ? 322 MET C C   1 
ATOM   10020 O O   . MET C 1 322 ? 119.612 129.893 166.771 1.00 55.84  ? 322 MET C O   1 
ATOM   10021 C CB  . MET C 1 322 ? 120.672 132.419 168.890 1.00 55.84  ? 322 MET C CB  1 
ATOM   10022 C CG  . MET C 1 322 ? 119.295 132.437 169.531 1.00 55.84  ? 322 MET C CG  1 
ATOM   10023 S SD  . MET C 1 322 ? 119.339 132.443 171.332 1.00 55.84  ? 322 MET C SD  1 
ATOM   10024 C CE  . MET C 1 322 ? 119.000 134.166 171.664 1.00 55.84  ? 322 MET C CE  1 
ATOM   10025 N N   . ARG C 1 323 ? 121.550 129.751 167.892 1.00 55.98  ? 323 ARG C N   1 
ATOM   10026 C CA  . ARG C 1 323 ? 121.523 128.296 167.904 1.00 55.98  ? 323 ARG C CA  1 
ATOM   10027 C C   . ARG C 1 323 ? 120.383 127.790 168.782 1.00 55.98  ? 323 ARG C C   1 
ATOM   10028 O O   . ARG C 1 323 ? 120.022 128.403 169.789 1.00 55.98  ? 323 ARG C O   1 
ATOM   10029 C CB  . ARG C 1 323 ? 122.859 127.736 168.394 1.00 55.98  ? 323 ARG C CB  1 
ATOM   10030 C CG  . ARG C 1 323 ? 123.348 128.336 169.695 1.00 55.98  ? 323 ARG C CG  1 
ATOM   10031 C CD  . ARG C 1 323 ? 124.512 127.543 170.270 1.00 55.98  ? 323 ARG C CD  1 
ATOM   10032 N NE  . ARG C 1 323 ? 125.794 127.970 169.724 1.00 55.98  ? 323 ARG C NE  1 
ATOM   10033 C CZ  . ARG C 1 323 ? 126.670 127.157 169.150 1.00 55.98  ? 323 ARG C CZ  1 
ATOM   10034 N NH1 . ARG C 1 323 ? 126.434 125.862 169.028 1.00 55.98  ? 323 ARG C NH1 1 
ATOM   10035 N NH2 . ARG C 1 323 ? 127.813 127.657 168.689 1.00 55.98  ? 323 ARG C NH2 1 
ATOM   10036 N N   . ASN C 1 324 ? 119.814 126.656 168.384 1.00 58.64  ? 324 ASN C N   1 
ATOM   10037 C CA  . ASN C 1 324 ? 118.633 126.092 169.029 1.00 58.64  ? 324 ASN C CA  1 
ATOM   10038 C C   . ASN C 1 324 ? 119.070 124.949 169.939 1.00 58.64  ? 324 ASN C C   1 
ATOM   10039 O O   . ASN C 1 324 ? 119.561 123.920 169.463 1.00 58.64  ? 324 ASN C O   1 
ATOM   10040 C CB  . ASN C 1 324 ? 117.633 125.614 167.979 1.00 58.64  ? 324 ASN C CB  1 
ATOM   10041 C CG  . ASN C 1 324 ? 116.226 125.488 168.522 1.00 58.64  ? 324 ASN C CG  1 
ATOM   10042 O OD1 . ASN C 1 324 ? 115.706 126.406 169.152 1.00 58.64  ? 324 ASN C OD1 1 
ATOM   10043 N ND2 . ASN C 1 324 ? 115.598 124.347 168.274 1.00 58.64  ? 324 ASN C ND2 1 
ATOM   10044 N N   . VAL C 1 325 ? 118.893 125.129 171.239 1.00 66.25  ? 325 VAL C N   1 
ATOM   10045 C CA  . VAL C 1 325 ? 119.288 124.150 172.251 1.00 66.25  ? 325 VAL C CA  1 
ATOM   10046 C C   . VAL C 1 325 ? 118.030 123.660 172.957 1.00 66.25  ? 325 VAL C C   1 
ATOM   10047 O O   . VAL C 1 325 ? 117.234 124.485 173.419 1.00 66.25  ? 325 VAL C O   1 
ATOM   10048 C CB  . VAL C 1 325 ? 120.281 124.746 173.268 1.00 66.25  ? 325 VAL C CB  1 
ATOM   10049 C CG1 . VAL C 1 325 ? 120.745 123.679 174.246 1.00 66.25  ? 325 VAL C CG1 1 
ATOM   10050 C CG2 . VAL C 1 325 ? 121.467 125.365 172.550 1.00 66.25  ? 325 VAL C CG2 1 
ATOM   10051 N N   . PRO C 1 326 ? 117.810 122.351 173.056 1.00 70.45  ? 326 PRO C N   1 
ATOM   10052 C CA  . PRO C 1 326 ? 116.614 121.854 173.747 1.00 70.45  ? 326 PRO C CA  1 
ATOM   10053 C C   . PRO C 1 326 ? 116.655 122.147 175.239 1.00 70.45  ? 326 PRO C C   1 
ATOM   10054 O O   . PRO C 1 326 ? 117.721 122.234 175.854 1.00 70.45  ? 326 PRO C O   1 
ATOM   10055 C CB  . PRO C 1 326 ? 116.648 120.342 173.483 1.00 70.45  ? 326 PRO C CB  1 
ATOM   10056 C CG  . PRO C 1 326 ? 117.650 120.145 172.386 1.00 70.45  ? 326 PRO C CG  1 
ATOM   10057 C CD  . PRO C 1 326 ? 118.635 121.257 172.523 1.00 70.45  ? 326 PRO C CD  1 
ATOM   10058 N N   . GLU C 1 327 ? 115.469 122.297 175.819 1.00 75.61  ? 327 GLU C N   1 
ATOM   10059 C CA  . GLU C 1 327 ? 115.346 122.507 177.256 1.00 75.61  ? 327 GLU C CA  1 
ATOM   10060 C C   . GLU C 1 327 ? 115.642 121.224 178.023 1.00 75.61  ? 327 GLU C C   1 
ATOM   10061 O O   . GLU C 1 327 ? 114.795 120.336 178.111 1.00 75.61  ? 327 GLU C O   1 
ATOM   10062 C CB  . GLU C 1 327 ? 113.949 123.016 177.610 1.00 75.61  ? 327 GLU C CB  1 
ATOM   10063 C CG  . GLU C 1 327 ? 113.761 123.302 179.091 1.00 75.61  ? 327 GLU C CG  1 
ATOM   10064 C CD  . GLU C 1 327 ? 113.050 124.614 179.347 1.00 75.61  ? 327 GLU C CD  1 
ATOM   10065 O OE1 . GLU C 1 327 ? 112.502 125.193 178.387 1.00 75.61  ? 327 GLU C OE1 1 
ATOM   10066 O OE2 . GLU C 1 327 ? 113.038 125.066 180.510 1.00 75.61  ? 327 GLU C OE2 1 
ATOM   10067 N N   . ILE C 1 337 ? 115.454 125.824 188.843 1.00 84.46  ? 337 ILE C N   1 
ATOM   10068 C CA  . ILE C 1 337 ? 115.593 126.490 187.556 1.00 84.46  ? 337 ILE C CA  1 
ATOM   10069 C C   . ILE C 1 337 ? 117.057 126.494 187.131 1.00 84.46  ? 337 ILE C C   1 
ATOM   10070 O O   . ILE C 1 337 ? 117.953 126.402 187.969 1.00 84.46  ? 337 ILE C O   1 
ATOM   10071 C CB  . ILE C 1 337 ? 115.020 127.916 187.608 1.00 84.46  ? 337 ILE C CB  1 
ATOM   10072 C CG1 . ILE C 1 337 ? 115.725 128.742 188.685 1.00 84.46  ? 337 ILE C CG1 1 
ATOM   10073 C CG2 . ILE C 1 337 ? 113.526 127.877 187.871 1.00 84.46  ? 337 ILE C CG2 1 
ATOM   10074 C CD1 . ILE C 1 337 ? 115.308 130.193 188.703 1.00 84.46  ? 337 ILE C CD1 1 
ATOM   10075 N N   . ALA C 1 338 ? 117.296 126.597 185.825 1.00 80.63  ? 338 ALA C N   1 
ATOM   10076 C CA  . ALA C 1 338 ? 118.635 126.505 185.264 1.00 80.63  ? 338 ALA C CA  1 
ATOM   10077 C C   . ALA C 1 338 ? 118.904 127.701 184.360 1.00 80.63  ? 338 ALA C C   1 
ATOM   10078 O O   . ALA C 1 338 ? 118.004 128.473 184.021 1.00 80.63  ? 338 ALA C O   1 
ATOM   10079 C CB  . ALA C 1 338 ? 118.825 125.197 184.485 1.00 80.63  ? 338 ALA C CB  1 
ATOM   10080 N N   . GLY C 1 339 ? 120.162 127.841 183.967 1.00 77.92  ? 339 GLY C N   1 
ATOM   10081 C CA  . GLY C 1 339 ? 120.624 128.937 183.144 1.00 77.92  ? 339 GLY C CA  1 
ATOM   10082 C C   . GLY C 1 339 ? 120.716 128.572 181.678 1.00 77.92  ? 339 GLY C C   1 
ATOM   10083 O O   . GLY C 1 339 ? 119.986 127.709 181.179 1.00 77.92  ? 339 GLY C O   1 
ATOM   10084 N N   . PHE C 1 340 ? 121.630 129.240 180.978 1.00 74.85  ? 340 PHE C N   1 
ATOM   10085 C CA  . PHE C 1 340 ? 121.799 129.077 179.540 1.00 74.85  ? 340 PHE C CA  1 
ATOM   10086 C C   . PHE C 1 340 ? 122.832 128.023 179.166 1.00 74.85  ? 340 PHE C C   1 
ATOM   10087 O O   . PHE C 1 340 ? 123.005 127.747 177.975 1.00 74.85  ? 340 PHE C O   1 
ATOM   10088 C CB  . PHE C 1 340 ? 122.188 130.416 178.901 1.00 74.85  ? 340 PHE C CB  1 
ATOM   10089 C CG  . PHE C 1 340 ? 123.545 130.918 179.314 1.00 74.85  ? 340 PHE C CG  1 
ATOM   10090 C CD1 . PHE C 1 340 ? 123.699 131.673 180.463 1.00 74.85  ? 340 PHE C CD1 1 
ATOM   10091 C CD2 . PHE C 1 340 ? 124.665 130.643 178.546 1.00 74.85  ? 340 PHE C CD2 1 
ATOM   10092 C CE1 . PHE C 1 340 ? 124.942 132.137 180.843 1.00 74.85  ? 340 PHE C CE1 1 
ATOM   10093 C CE2 . PHE C 1 340 ? 125.911 131.102 178.922 1.00 74.85  ? 340 PHE C CE2 1 
ATOM   10094 C CZ  . PHE C 1 340 ? 126.049 131.851 180.071 1.00 74.85  ? 340 PHE C CZ  1 
ATOM   10095 N N   . ILE C 1 341 ? 123.523 127.431 180.136 1.00 77.23  ? 341 ILE C N   1 
ATOM   10096 C CA  . ILE C 1 341 ? 124.585 126.479 179.825 1.00 77.23  ? 341 ILE C CA  1 
ATOM   10097 C C   . ILE C 1 341 ? 123.945 125.182 179.337 1.00 77.23  ? 341 ILE C C   1 
ATOM   10098 O O   . ILE C 1 341 ? 123.399 124.410 180.129 1.00 77.23  ? 341 ILE C O   1 
ATOM   10099 C CB  . ILE C 1 341 ? 125.497 126.236 181.032 1.00 77.23  ? 341 ILE C CB  1 
ATOM   10100 C CG1 . ILE C 1 341 ? 125.843 127.564 181.709 1.00 77.23  ? 341 ILE C CG1 1 
ATOM   10101 C CG2 . ILE C 1 341 ? 126.760 125.502 180.609 1.00 77.23  ? 341 ILE C CG2 1 
ATOM   10102 C CD1 . ILE C 1 341 ? 126.970 128.323 181.047 1.00 77.23  ? 341 ILE C CD1 1 
ATOM   10103 N N   . GLU C 1 342 ? 124.010 124.950 178.023 1.00 77.31  ? 342 GLU C N   1 
ATOM   10104 C CA  . GLU C 1 342 ? 123.479 123.741 177.387 1.00 77.31  ? 342 GLU C CA  1 
ATOM   10105 C C   . GLU C 1 342 ? 122.006 123.527 177.728 1.00 77.31  ? 342 GLU C C   1 
ATOM   10106 O O   . GLU C 1 342 ? 121.550 122.400 177.925 1.00 77.31  ? 342 GLU C O   1 
ATOM   10107 C CB  . GLU C 1 342 ? 124.312 122.512 177.761 1.00 77.31  ? 342 GLU C CB  1 
ATOM   10108 C CG  . GLU C 1 342 ? 125.792 122.651 177.448 1.00 77.31  ? 342 GLU C CG  1 
ATOM   10109 C CD  . GLU C 1 342 ? 126.326 121.503 176.611 1.00 77.31  ? 342 GLU C CD  1 
ATOM   10110 O OE1 . GLU C 1 342 ? 125.902 121.369 175.444 1.00 77.31  ? 342 GLU C OE1 1 
ATOM   10111 O OE2 . GLU C 1 342 ? 127.171 120.736 177.119 1.00 77.31  ? 342 GLU C OE2 1 
ATOM   10112 N N   . ASN C 1 343 ? 121.250 124.621 177.791 1.00 75.17  ? 343 ASN C N   1 
ATOM   10113 C CA  . ASN C 1 343 ? 119.831 124.538 178.128 1.00 75.17  ? 343 ASN C CA  1 
ATOM   10114 C C   . ASN C 1 343 ? 119.128 125.779 177.603 1.00 75.17  ? 343 ASN C C   1 
ATOM   10115 O O   . ASN C 1 343 ? 119.529 126.901 177.926 1.00 75.17  ? 343 ASN C O   1 
ATOM   10116 C CB  . ASN C 1 343 ? 119.638 124.401 179.641 1.00 75.17  ? 343 ASN C CB  1 
ATOM   10117 C CG  . ASN C 1 343 ? 118.215 124.700 180.077 1.00 75.17  ? 343 ASN C CG  1 
ATOM   10118 O OD1 . ASN C 1 343 ? 117.291 123.948 179.772 1.00 75.17  ? 343 ASN C OD1 1 
ATOM   10119 N ND2 . ASN C 1 343 ? 118.035 125.800 180.798 1.00 75.17  ? 343 ASN C ND2 1 
ATOM   10120 N N   . GLY C 1 344 ? 118.087 125.580 176.800 1.00 73.06  ? 344 GLY C N   1 
ATOM   10121 C CA  . GLY C 1 344 ? 117.287 126.681 176.301 1.00 73.06  ? 344 GLY C CA  1 
ATOM   10122 C C   . GLY C 1 344 ? 115.940 126.757 176.988 1.00 73.06  ? 344 GLY C C   1 
ATOM   10123 O O   . GLY C 1 344 ? 115.520 125.795 177.635 1.00 73.06  ? 344 GLY C O   1 
ATOM   10124 N N   . TRP C 1 345 ? 115.252 127.888 176.864 1.00 74.19  ? 345 TRP C N   1 
ATOM   10125 C CA  . TRP C 1 345 ? 113.961 128.095 177.518 1.00 74.19  ? 345 TRP C CA  1 
ATOM   10126 C C   . TRP C 1 345 ? 112.865 128.048 176.460 1.00 74.19  ? 345 TRP C C   1 
ATOM   10127 O O   . TRP C 1 345 ? 112.637 129.024 175.741 1.00 74.19  ? 345 TRP C O   1 
ATOM   10128 C CB  . TRP C 1 345 ? 113.939 129.418 178.277 1.00 74.19  ? 345 TRP C CB  1 
ATOM   10129 C CG  . TRP C 1 345 ? 114.790 129.426 179.508 1.00 74.19  ? 345 TRP C CG  1 
ATOM   10130 C CD1 . TRP C 1 345 ? 115.373 128.350 180.108 1.00 74.19  ? 345 TRP C CD1 1 
ATOM   10131 C CD2 . TRP C 1 345 ? 115.144 130.567 180.297 1.00 74.19  ? 345 TRP C CD2 1 
ATOM   10132 N NE1 . TRP C 1 345 ? 116.075 128.751 181.219 1.00 74.19  ? 345 TRP C NE1 1 
ATOM   10133 C CE2 . TRP C 1 345 ? 115.948 130.107 181.357 1.00 74.19  ? 345 TRP C CE2 1 
ATOM   10134 C CE3 . TRP C 1 345 ? 114.862 131.932 180.207 1.00 74.19  ? 345 TRP C CE3 1 
ATOM   10135 C CZ2 . TRP C 1 345 ? 116.473 130.964 182.320 1.00 74.19  ? 345 TRP C CZ2 1 
ATOM   10136 C CZ3 . TRP C 1 345 ? 115.384 132.781 181.165 1.00 74.19  ? 345 TRP C CZ3 1 
ATOM   10137 C CH2 . TRP C 1 345 ? 116.180 132.294 182.207 1.00 74.19  ? 345 TRP C CH2 1 
ATOM   10138 N N   . GLU C 1 346 ? 112.180 126.906 176.369 1.00 76.06  ? 346 GLU C N   1 
ATOM   10139 C CA  . GLU C 1 346 ? 111.051 126.778 175.456 1.00 76.06  ? 346 GLU C CA  1 
ATOM   10140 C C   . GLU C 1 346 ? 109.826 127.554 175.918 1.00 76.06  ? 346 GLU C C   1 
ATOM   10141 O O   . GLU C 1 346 ? 108.918 127.778 175.111 1.00 76.06  ? 346 GLU C O   1 
ATOM   10142 C CB  . GLU C 1 346 ? 110.680 125.305 175.273 1.00 76.06  ? 346 GLU C CB  1 
ATOM   10143 C CG  . GLU C 1 346 ? 111.327 124.651 174.066 1.00 76.06  ? 346 GLU C CG  1 
ATOM   10144 C CD  . GLU C 1 346 ? 110.578 123.417 173.599 1.00 76.06  ? 346 GLU C CD  1 
ATOM   10145 O OE1 . GLU C 1 346 ? 109.495 123.134 174.152 1.00 76.06  ? 346 GLU C OE1 1 
ATOM   10146 O OE2 . GLU C 1 346 ? 111.074 122.730 172.682 1.00 76.06  ? 346 GLU C OE2 1 
ATOM   10147 N N   . GLY C 1 347 ? 109.779 127.969 177.178 1.00 77.57  ? 347 GLY C N   1 
ATOM   10148 C CA  . GLY C 1 347 ? 108.655 128.697 177.723 1.00 77.57  ? 347 GLY C CA  1 
ATOM   10149 C C   . GLY C 1 347 ? 108.741 130.203 177.611 1.00 77.57  ? 347 GLY C C   1 
ATOM   10150 O O   . GLY C 1 347 ? 107.932 130.902 178.230 1.00 77.57  ? 347 GLY C O   1 
ATOM   10151 N N   . MET C 1 348 ? 109.694 130.729 176.849 1.00 77.68  ? 348 MET C N   1 
ATOM   10152 C CA  . MET C 1 348 ? 109.889 132.166 176.709 1.00 77.68  ? 348 MET C CA  1 
ATOM   10153 C C   . MET C 1 348 ? 109.444 132.595 175.318 1.00 77.68  ? 348 MET C C   1 
ATOM   10154 O O   . MET C 1 348 ? 110.006 132.143 174.315 1.00 77.68  ? 348 MET C O   1 
ATOM   10155 C CB  . MET C 1 348 ? 111.350 132.544 176.948 1.00 77.68  ? 348 MET C CB  1 
ATOM   10156 C CG  . MET C 1 348 ? 111.624 134.033 176.879 1.00 77.68  ? 348 MET C CG  1 
ATOM   10157 S SD  . MET C 1 348 ? 112.992 134.530 177.940 1.00 77.68  ? 348 MET C SD  1 
ATOM   10158 C CE  . MET C 1 348 ? 114.373 134.339 176.818 1.00 77.68  ? 348 MET C CE  1 
ATOM   10159 N N   . ILE C 1 349 ? 108.437 133.469 175.262 1.00 79.21  ? 349 ILE C N   1 
ATOM   10160 C CA  . ILE C 1 349 ? 107.938 134.008 174.004 1.00 79.21  ? 349 ILE C CA  1 
ATOM   10161 C C   . ILE C 1 349 ? 107.921 135.528 173.984 1.00 79.21  ? 349 ILE C C   1 
ATOM   10162 O O   . ILE C 1 349 ? 107.289 136.115 173.104 1.00 79.21  ? 349 ILE C O   1 
ATOM   10163 C CB  . ILE C 1 349 ? 106.536 133.454 173.670 1.00 79.21  ? 349 ILE C CB  1 
ATOM   10164 C CG1 . ILE C 1 349 ? 105.620 133.496 174.899 1.00 79.21  ? 349 ILE C CG1 1 
ATOM   10165 C CG2 . ILE C 1 349 ? 106.639 132.036 173.130 1.00 79.21  ? 349 ILE C CG2 1 
ATOM   10166 C CD1 . ILE C 1 349 ? 104.892 134.811 175.100 1.00 79.21  ? 349 ILE C CD1 1 
ATOM   10167 N N   . ASP C 1 350 ? 108.589 136.185 174.928 1.00 78.73  ? 350 ASP C N   1 
ATOM   10168 C CA  . ASP C 1 350 ? 108.570 137.637 175.035 1.00 78.73  ? 350 ASP C CA  1 
ATOM   10169 C C   . ASP C 1 350 ? 109.841 138.295 174.517 1.00 78.73  ? 350 ASP C C   1 
ATOM   10170 O O   . ASP C 1 350 ? 109.884 139.525 174.412 1.00 78.73  ? 350 ASP C O   1 
ATOM   10171 C CB  . ASP C 1 350 ? 108.344 138.047 176.493 1.00 78.73  ? 350 ASP C CB  1 
ATOM   10172 C CG  . ASP C 1 350 ? 107.686 139.400 176.620 1.00 78.73  ? 350 ASP C CG  1 
ATOM   10173 O OD1 . ASP C 1 350 ? 106.908 139.767 175.716 1.00 78.73  ? 350 ASP C OD1 1 
ATOM   10174 O OD2 . ASP C 1 350 ? 107.947 140.096 177.622 1.00 78.73  ? 350 ASP C OD2 1 
ATOM   10175 N N   . GLY C 1 351 ? 110.864 137.515 174.194 1.00 73.28  ? 351 GLY C N   1 
ATOM   10176 C CA  . GLY C 1 351 ? 112.117 138.079 173.736 1.00 73.28  ? 351 GLY C CA  1 
ATOM   10177 C C   . GLY C 1 351 ? 113.111 136.979 173.445 1.00 73.28  ? 351 GLY C C   1 
ATOM   10178 O O   . GLY C 1 351 ? 112.770 135.795 173.436 1.00 73.28  ? 351 GLY C O   1 
ATOM   10179 N N   . TRP C 1 352 ? 114.355 137.386 173.202 1.00 66.12  ? 352 TRP C N   1 
ATOM   10180 C CA  . TRP C 1 352 ? 115.426 136.441 172.913 1.00 66.12  ? 352 TRP C CA  1 
ATOM   10181 C C   . TRP C 1 352 ? 116.246 136.085 174.144 1.00 66.12  ? 352 TRP C C   1 
ATOM   10182 O O   . TRP C 1 352 ? 116.573 134.913 174.344 1.00 66.12  ? 352 TRP C O   1 
ATOM   10183 C CB  . TRP C 1 352 ? 116.349 137.001 171.825 1.00 66.12  ? 352 TRP C CB  1 
ATOM   10184 C CG  . TRP C 1 352 ? 115.749 136.966 170.450 1.00 66.12  ? 352 TRP C CG  1 
ATOM   10185 C CD1 . TRP C 1 352 ? 114.427 136.850 170.134 1.00 66.12  ? 352 TRP C CD1 1 
ATOM   10186 C CD2 . TRP C 1 352 ? 116.453 137.047 169.205 1.00 66.12  ? 352 TRP C CD2 1 
ATOM   10187 N NE1 . TRP C 1 352 ? 114.263 136.854 168.772 1.00 66.12  ? 352 TRP C NE1 1 
ATOM   10188 C CE2 . TRP C 1 352 ? 115.492 136.975 168.178 1.00 66.12  ? 352 TRP C CE2 1 
ATOM   10189 C CE3 . TRP C 1 352 ? 117.800 137.175 168.860 1.00 66.12  ? 352 TRP C CE3 1 
ATOM   10190 C CZ2 . TRP C 1 352 ? 115.836 137.026 166.829 1.00 66.12  ? 352 TRP C CZ2 1 
ATOM   10191 C CZ3 . TRP C 1 352 ? 118.140 137.224 167.522 1.00 66.12  ? 352 TRP C CZ3 1 
ATOM   10192 C CH2 . TRP C 1 352 ? 117.162 137.150 166.523 1.00 66.12  ? 352 TRP C CH2 1 
ATOM   10193 N N   . TYR C 1 353 ? 116.579 137.068 174.975 1.00 66.88  ? 353 TYR C N   1 
ATOM   10194 C CA  . TYR C 1 353 ? 117.316 136.863 176.211 1.00 66.88  ? 353 TYR C CA  1 
ATOM   10195 C C   . TYR C 1 353 ? 116.459 137.319 177.384 1.00 66.88  ? 353 TYR C C   1 
ATOM   10196 O O   . TYR C 1 353 ? 115.609 138.201 177.239 1.00 66.88  ? 353 TYR C O   1 
ATOM   10197 C CB  . TYR C 1 353 ? 118.639 137.635 176.205 1.00 66.88  ? 353 TYR C CB  1 
ATOM   10198 C CG  . TYR C 1 353 ? 119.476 137.420 174.966 1.00 66.88  ? 353 TYR C CG  1 
ATOM   10199 C CD1 . TYR C 1 353 ? 120.378 136.369 174.890 1.00 66.88  ? 353 TYR C CD1 1 
ATOM   10200 C CD2 . TYR C 1 353 ? 119.366 138.269 173.873 1.00 66.88  ? 353 TYR C CD2 1 
ATOM   10201 C CE1 . TYR C 1 353 ? 121.145 136.169 173.763 1.00 66.88  ? 353 TYR C CE1 1 
ATOM   10202 C CE2 . TYR C 1 353 ? 120.129 138.075 172.740 1.00 66.88  ? 353 TYR C CE2 1 
ATOM   10203 C CZ  . TYR C 1 353 ? 121.017 137.023 172.692 1.00 66.88  ? 353 TYR C CZ  1 
ATOM   10204 O OH  . TYR C 1 353 ? 121.781 136.824 171.568 1.00 66.88  ? 353 TYR C OH  1 
ATOM   10205 N N   . GLY C 1 354 ? 116.684 136.721 178.550 1.00 73.08  ? 354 GLY C N   1 
ATOM   10206 C CA  . GLY C 1 354 ? 115.862 137.093 179.687 1.00 73.08  ? 354 GLY C CA  1 
ATOM   10207 C C   . GLY C 1 354 ? 116.378 136.547 181.000 1.00 73.08  ? 354 GLY C C   1 
ATOM   10208 O O   . GLY C 1 354 ? 117.353 135.790 181.057 1.00 73.08  ? 354 GLY C O   1 
ATOM   10209 N N   . PHE C 1 355 ? 115.681 136.949 182.061 1.00 77.95  ? 355 PHE C N   1 
ATOM   10210 C CA  . PHE C 1 355 ? 115.972 136.577 183.436 1.00 77.95  ? 355 PHE C CA  1 
ATOM   10211 C C   . PHE C 1 355 ? 114.851 135.711 183.993 1.00 77.95  ? 355 PHE C C   1 
ATOM   10212 O O   . PHE C 1 355 ? 113.687 135.837 183.600 1.00 77.95  ? 355 PHE C O   1 
ATOM   10213 C CB  . PHE C 1 355 ? 116.113 137.807 184.343 1.00 77.95  ? 355 PHE C CB  1 
ATOM   10214 C CG  . PHE C 1 355 ? 117.155 138.795 183.906 1.00 77.95  ? 355 PHE C CG  1 
ATOM   10215 C CD1 . PHE C 1 355 ? 116.862 139.756 182.954 1.00 77.95  ? 355 PHE C CD1 1 
ATOM   10216 C CD2 . PHE C 1 355 ? 118.413 138.793 184.483 1.00 77.95  ? 355 PHE C CD2 1 
ATOM   10217 C CE1 . PHE C 1 355 ? 117.813 140.679 182.566 1.00 77.95  ? 355 PHE C CE1 1 
ATOM   10218 C CE2 . PHE C 1 355 ? 119.368 139.713 184.099 1.00 77.95  ? 355 PHE C CE2 1 
ATOM   10219 C CZ  . PHE C 1 355 ? 119.067 140.657 183.139 1.00 77.95  ? 355 PHE C CZ  1 
ATOM   10220 N N   . ARG C 1 356 ? 115.214 134.842 184.928 1.00 80.26  ? 356 ARG C N   1 
ATOM   10221 C CA  . ARG C 1 356 ? 114.265 134.115 185.756 1.00 80.26  ? 356 ARG C CA  1 
ATOM   10222 C C   . ARG C 1 356 ? 114.717 134.236 187.202 1.00 80.26  ? 356 ARG C C   1 
ATOM   10223 O O   . ARG C 1 356 ? 115.917 134.299 187.477 1.00 80.26  ? 356 ARG C O   1 
ATOM   10224 C CB  . ARG C 1 356 ? 114.174 132.644 185.350 1.00 80.26  ? 356 ARG C CB  1 
ATOM   10225 C CG  . ARG C 1 356 ? 113.173 132.365 184.247 1.00 80.26  ? 356 ARG C CG  1 
ATOM   10226 C CD  . ARG C 1 356 ? 113.096 130.879 183.958 1.00 80.26  ? 356 ARG C CD  1 
ATOM   10227 N NE  . ARG C 1 356 ? 112.235 130.588 182.819 1.00 80.26  ? 356 ARG C NE  1 
ATOM   10228 C CZ  . ARG C 1 356 ? 112.109 129.391 182.265 1.00 80.26  ? 356 ARG C CZ  1 
ATOM   10229 N NH1 . ARG C 1 356 ? 112.779 128.345 182.718 1.00 80.26  ? 356 ARG C NH1 1 
ATOM   10230 N NH2 . ARG C 1 356 ? 111.293 129.240 181.227 1.00 80.26  ? 356 ARG C NH2 1 
ATOM   10231 N N   . HIS C 1 357 ? 113.767 134.289 188.128 1.00 88.38  ? 357 HIS C N   1 
ATOM   10232 C CA  . HIS C 1 357 ? 114.111 134.402 189.537 1.00 88.38  ? 357 HIS C CA  1 
ATOM   10233 C C   . HIS C 1 357 ? 113.280 133.438 190.368 1.00 88.38  ? 357 HIS C C   1 
ATOM   10234 O O   . HIS C 1 357 ? 112.096 133.221 190.096 1.00 88.38  ? 357 HIS C O   1 
ATOM   10235 C CB  . HIS C 1 357 ? 113.950 135.850 190.045 1.00 88.38  ? 357 HIS C CB  1 
ATOM   10236 C CG  . HIS C 1 357 ? 112.542 136.358 190.040 1.00 88.38  ? 357 HIS C CG  1 
ATOM   10237 N ND1 . HIS C 1 357 ? 112.119 137.354 189.186 1.00 88.38  ? 357 HIS C ND1 1 
ATOM   10238 C CD2 . HIS C 1 357 ? 111.474 136.047 190.813 1.00 88.38  ? 357 HIS C CD2 1 
ATOM   10239 C CE1 . HIS C 1 357 ? 110.844 137.614 189.414 1.00 88.38  ? 357 HIS C CE1 1 
ATOM   10240 N NE2 . HIS C 1 357 ? 110.429 136.835 190.397 1.00 88.38  ? 357 HIS C NE2 1 
ATOM   10241 N N   . GLN C 1 358 ? 113.929 132.845 191.366 1.00 92.79  ? 358 GLN C N   1 
ATOM   10242 C CA  . GLN C 1 358 ? 113.301 131.942 192.319 1.00 92.79  ? 358 GLN C CA  1 
ATOM   10243 C C   . GLN C 1 358 ? 113.433 132.552 193.706 1.00 92.79  ? 358 GLN C C   1 
ATOM   10244 O O   . GLN C 1 358 ? 114.538 132.918 194.126 1.00 92.79  ? 358 GLN C O   1 
ATOM   10245 C CB  . GLN C 1 358 ? 113.945 130.556 192.273 1.00 92.79  ? 358 GLN C CB  1 
ATOM   10246 C CG  . GLN C 1 358 ? 113.048 129.436 192.763 1.00 92.79  ? 358 GLN C CG  1 
ATOM   10247 C CD  . GLN C 1 358 ? 113.780 128.115 192.860 1.00 92.79  ? 358 GLN C CD  1 
ATOM   10248 O OE1 . GLN C 1 358 ? 114.807 128.011 193.529 1.00 92.79  ? 358 GLN C OE1 1 
ATOM   10249 N NE2 . GLN C 1 358 ? 113.260 127.099 192.183 1.00 92.79  ? 358 GLN C NE2 1 
ATOM   10250 N N   . ASN C 1 359 ? 112.311 132.644 194.415 1.00 97.78  ? 359 ASN C N   1 
ATOM   10251 C CA  . ASN C 1 359 ? 112.211 133.503 195.583 1.00 97.78  ? 359 ASN C CA  1 
ATOM   10252 C C   . ASN C 1 359 ? 111.162 132.941 196.534 1.00 97.78  ? 359 ASN C C   1 
ATOM   10253 O O   . ASN C 1 359 ? 110.514 131.928 196.252 1.00 97.78  ? 359 ASN C O   1 
ATOM   10254 C CB  . ASN C 1 359 ? 111.864 134.931 195.155 1.00 97.78  ? 359 ASN C CB  1 
ATOM   10255 C CG  . ASN C 1 359 ? 112.396 135.969 196.105 1.00 97.78  ? 359 ASN C CG  1 
ATOM   10256 O OD1 . ASN C 1 359 ? 113.194 135.668 196.992 1.00 97.78  ? 359 ASN C OD1 1 
ATOM   10257 N ND2 . ASN C 1 359 ? 111.953 137.204 195.930 1.00 97.78  ? 359 ASN C ND2 1 
ATOM   10258 N N   . SER C 1 360 ? 111.005 133.611 197.679 1.00 99.42  ? 360 SER C N   1 
ATOM   10259 C CA  . SER C 1 360 ? 109.976 133.220 198.638 1.00 99.42  ? 360 SER C CA  1 
ATOM   10260 C C   . SER C 1 360 ? 108.579 133.413 198.061 1.00 99.42  ? 360 SER C C   1 
ATOM   10261 O O   . SER C 1 360 ? 107.695 132.574 198.270 1.00 99.42  ? 360 SER C O   1 
ATOM   10262 C CB  . SER C 1 360 ? 110.140 134.015 199.933 1.00 99.42  ? 360 SER C CB  1 
ATOM   10263 O OG  . SER C 1 360 ? 109.923 135.398 199.715 1.00 99.42  ? 360 SER C OG  1 
ATOM   10264 N N   . GLU C 1 361 ? 108.359 134.516 197.340 1.00 99.75  ? 361 GLU C N   1 
ATOM   10265 C CA  . GLU C 1 361 ? 107.070 134.729 196.688 1.00 99.75  ? 361 GLU C CA  1 
ATOM   10266 C C   . GLU C 1 361 ? 106.803 133.661 195.637 1.00 99.75  ? 361 GLU C C   1 
ATOM   10267 O O   . GLU C 1 361 ? 105.673 133.176 195.503 1.00 99.75  ? 361 GLU C O   1 
ATOM   10268 C CB  . GLU C 1 361 ? 107.025 136.120 196.057 1.00 99.75  ? 361 GLU C CB  1 
ATOM   10269 C CG  . GLU C 1 361 ? 106.596 137.225 197.002 1.00 99.75  ? 361 GLU C CG  1 
ATOM   10270 C CD  . GLU C 1 361 ? 107.446 138.469 196.853 1.00 99.75  ? 361 GLU C CD  1 
ATOM   10271 O OE1 . GLU C 1 361 ? 108.670 138.327 196.648 1.00 99.75  ? 361 GLU C OE1 1 
ATOM   10272 O OE2 . GLU C 1 361 ? 106.892 139.586 196.930 1.00 99.75  ? 361 GLU C OE2 1 
ATOM   10273 N N   . GLY C 1 362 ? 107.828 133.286 194.878 1.00 96.90  ? 362 GLY C N   1 
ATOM   10274 C CA  . GLY C 1 362 ? 107.681 132.264 193.862 1.00 96.90  ? 362 GLY C CA  1 
ATOM   10275 C C   . GLY C 1 362 ? 108.518 132.539 192.633 1.00 96.90  ? 362 GLY C C   1 
ATOM   10276 O O   . GLY C 1 362 ? 109.238 133.540 192.575 1.00 96.90  ? 362 GLY C O   1 
ATOM   10277 N N   . THR C 1 363 ? 108.434 131.655 191.644 1.00 92.87  ? 363 THR C N   1 
ATOM   10278 C CA  . THR C 1 363 ? 109.192 131.836 190.415 1.00 92.87  ? 363 THR C CA  1 
ATOM   10279 C C   . THR C 1 363 ? 108.612 132.973 189.582 1.00 92.87  ? 363 THR C C   1 
ATOM   10280 O O   . THR C 1 363 ? 107.401 133.207 189.571 1.00 92.87  ? 363 THR C O   1 
ATOM   10281 C CB  . THR C 1 363 ? 109.200 130.544 189.598 1.00 92.87  ? 363 THR C CB  1 
ATOM   10282 O OG1 . THR C 1 363 ? 107.886 130.292 189.086 1.00 92.87  ? 363 THR C OG1 1 
ATOM   10283 C CG2 . THR C 1 363 ? 109.639 129.370 190.461 1.00 92.87  ? 363 THR C CG2 1 
ATOM   10284 N N   . GLY C 1 364 ? 109.497 133.685 188.886 1.00 86.91  ? 364 GLY C N   1 
ATOM   10285 C CA  . GLY C 1 364 ? 109.085 134.738 187.982 1.00 86.91  ? 364 GLY C CA  1 
ATOM   10286 C C   . GLY C 1 364 ? 110.034 134.813 186.802 1.00 86.91  ? 364 GLY C C   1 
ATOM   10287 O O   . GLY C 1 364 ? 111.167 134.335 186.862 1.00 86.91  ? 364 GLY C O   1 
ATOM   10288 N N   . GLN C 1 365 ? 109.554 135.432 185.724 1.00 81.12  ? 365 GLN C N   1 
ATOM   10289 C CA  . GLN C 1 365 ? 110.292 135.472 184.470 1.00 81.12  ? 365 GLN C CA  1 
ATOM   10290 C C   . GLN C 1 365 ? 110.141 136.841 183.823 1.00 81.12  ? 365 GLN C C   1 
ATOM   10291 O O   . GLN C 1 365 ? 109.111 137.503 183.969 1.00 81.12  ? 365 GLN C O   1 
ATOM   10292 C CB  . GLN C 1 365 ? 109.804 134.373 183.514 1.00 81.12  ? 365 GLN C CB  1 
ATOM   10293 C CG  . GLN C 1 365 ? 110.623 134.212 182.246 1.00 81.12  ? 365 GLN C CG  1 
ATOM   10294 C CD  . GLN C 1 365 ? 110.317 132.915 181.519 1.00 81.12  ? 365 GLN C CD  1 
ATOM   10295 O OE1 . GLN C 1 365 ? 109.656 132.028 182.059 1.00 81.12  ? 365 GLN C OE1 1 
ATOM   10296 N NE2 . GLN C 1 365 ? 110.797 132.799 180.288 1.00 81.12  ? 365 GLN C NE2 1 
ATOM   10297 N N   . ALA C 1 366 ? 111.181 137.260 183.104 1.00 78.37  ? 366 ALA C N   1 
ATOM   10298 C CA  . ALA C 1 366 ? 111.152 138.521 182.375 1.00 78.37  ? 366 ALA C CA  1 
ATOM   10299 C C   . ALA C 1 366 ? 112.180 138.453 181.256 1.00 78.37  ? 366 ALA C C   1 
ATOM   10300 O O   . ALA C 1 366 ? 112.996 137.532 181.192 1.00 78.37  ? 366 ALA C O   1 
ATOM   10301 C CB  . ALA C 1 366 ? 111.420 139.714 183.295 1.00 78.37  ? 366 ALA C CB  1 
ATOM   10302 N N   . ALA C 1 367 ? 112.145 139.457 180.384 1.00 74.19  ? 367 ALA C N   1 
ATOM   10303 C CA  . ALA C 1 367 ? 113.009 139.515 179.217 1.00 74.19  ? 367 ALA C CA  1 
ATOM   10304 C C   . ALA C 1 367 ? 113.841 140.791 179.235 1.00 74.19  ? 367 ALA C C   1 
ATOM   10305 O O   . ALA C 1 367 ? 113.483 141.786 179.871 1.00 74.19  ? 367 ALA C O   1 
ATOM   10306 C CB  . ALA C 1 367 ? 112.196 139.439 177.920 1.00 74.19  ? 367 ALA C CB  1 
ATOM   10307 N N   . ASP C 1 368 ? 114.964 140.748 178.524 1.00 71.75  ? 368 ASP C N   1 
ATOM   10308 C CA  . ASP C 1 368 ? 115.894 141.866 178.426 1.00 71.75  ? 368 ASP C CA  1 
ATOM   10309 C C   . ASP C 1 368 ? 115.751 142.499 177.049 1.00 71.75  ? 368 ASP C C   1 
ATOM   10310 O O   . ASP C 1 368 ? 116.059 141.864 176.035 1.00 71.75  ? 368 ASP C O   1 
ATOM   10311 C CB  . ASP C 1 368 ? 117.330 141.400 178.664 1.00 71.75  ? 368 ASP C CB  1 
ATOM   10312 C CG  . ASP C 1 368 ? 118.261 142.537 179.031 1.00 71.75  ? 368 ASP C CG  1 
ATOM   10313 O OD1 . ASP C 1 368 ? 118.236 143.580 178.346 1.00 71.75  ? 368 ASP C OD1 1 
ATOM   10314 O OD2 . ASP C 1 368 ? 119.017 142.390 180.012 1.00 71.75  ? 368 ASP C OD2 1 
ATOM   10315 N N   . LEU C 1 369 ? 115.291 143.750 177.017 1.00 69.63  ? 369 LEU C N   1 
ATOM   10316 C CA  . LEU C 1 369 ? 115.023 144.412 175.746 1.00 69.63  ? 369 LEU C CA  1 
ATOM   10317 C C   . LEU C 1 369 ? 116.300 144.887 175.063 1.00 69.63  ? 369 LEU C C   1 
ATOM   10318 O O   . LEU C 1 369 ? 116.391 144.854 173.832 1.00 69.63  ? 369 LEU C O   1 
ATOM   10319 C CB  . LEU C 1 369 ? 114.067 145.587 175.958 1.00 69.63  ? 369 LEU C CB  1 
ATOM   10320 C CG  . LEU C 1 369 ? 112.813 145.305 176.788 1.00 69.63  ? 369 LEU C CG  1 
ATOM   10321 C CD1 . LEU C 1 369 ? 111.898 146.521 176.814 1.00 69.63  ? 369 LEU C CD1 1 
ATOM   10322 C CD2 . LEU C 1 369 ? 112.074 144.086 176.255 1.00 69.63  ? 369 LEU C CD2 1 
ATOM   10323 N N   . LYS C 1 370 ? 117.293 145.332 175.836 1.00 68.70  ? 370 LYS C N   1 
ATOM   10324 C CA  . LYS C 1 370 ? 118.481 145.941 175.241 1.00 68.70  ? 370 LYS C CA  1 
ATOM   10325 C C   . LYS C 1 370 ? 119.291 144.928 174.437 1.00 68.70  ? 370 LYS C C   1 
ATOM   10326 O O   . LYS C 1 370 ? 119.660 145.190 173.285 1.00 68.70  ? 370 LYS C O   1 
ATOM   10327 C CB  . LYS C 1 370 ? 119.343 146.575 176.332 1.00 68.70  ? 370 LYS C CB  1 
ATOM   10328 C CG  . LYS C 1 370 ? 118.684 147.747 177.039 1.00 68.70  ? 370 LYS C CG  1 
ATOM   10329 C CD  . LYS C 1 370 ? 119.610 148.357 178.077 1.00 68.70  ? 370 LYS C CD  1 
ATOM   10330 C CE  . LYS C 1 370 ? 118.994 149.592 178.711 1.00 68.70  ? 370 LYS C CE  1 
ATOM   10331 N NZ  . LYS C 1 370 ? 119.907 150.220 179.705 1.00 68.70  ? 370 LYS C NZ  1 
ATOM   10332 N N   . SER C 1 371 ? 119.584 143.767 175.029 1.00 67.65  ? 371 SER C N   1 
ATOM   10333 C CA  . SER C 1 371 ? 120.387 142.767 174.330 1.00 67.65  ? 371 SER C CA  1 
ATOM   10334 C C   . SER C 1 371 ? 119.635 142.185 173.139 1.00 67.65  ? 371 SER C C   1 
ATOM   10335 O O   . SER C 1 371 ? 120.226 141.950 172.077 1.00 67.65  ? 371 SER C O   1 
ATOM   10336 C CB  . SER C 1 371 ? 120.811 141.665 175.300 1.00 67.65  ? 371 SER C CB  1 
ATOM   10337 O OG  . SER C 1 371 ? 119.691 141.093 175.950 1.00 67.65  ? 371 SER C OG  1 
ATOM   10338 N N   . THR C 1 372 ? 118.329 141.954 173.296 1.00 65.82  ? 372 THR C N   1 
ATOM   10339 C CA  . THR C 1 372 ? 117.516 141.486 172.178 1.00 65.82  ? 372 THR C CA  1 
ATOM   10340 C C   . THR C 1 372 ? 117.543 142.485 171.028 1.00 65.82  ? 372 THR C C   1 
ATOM   10341 O O   . THR C 1 372 ? 117.715 142.106 169.863 1.00 65.82  ? 372 THR C O   1 
ATOM   10342 C CB  . THR C 1 372 ? 116.079 141.245 172.642 1.00 65.82  ? 372 THR C CB  1 
ATOM   10343 O OG1 . THR C 1 372 ? 116.066 140.258 173.681 1.00 65.82  ? 372 THR C OG1 1 
ATOM   10344 C CG2 . THR C 1 372 ? 115.219 140.768 171.487 1.00 65.82  ? 372 THR C CG2 1 
ATOM   10345 N N   . GLN C 1 373 ? 117.381 143.772 171.343 1.00 65.06  ? 373 GLN C N   1 
ATOM   10346 C CA  . GLN C 1 373 ? 117.394 144.797 170.306 1.00 65.06  ? 373 GLN C CA  1 
ATOM   10347 C C   . GLN C 1 373 ? 118.752 144.878 169.626 1.00 65.06  ? 373 GLN C C   1 
ATOM   10348 O O   . GLN C 1 373 ? 118.831 145.033 168.403 1.00 65.06  ? 373 GLN C O   1 
ATOM   10349 C CB  . GLN C 1 373 ? 117.011 146.152 170.900 1.00 65.06  ? 373 GLN C CB  1 
ATOM   10350 C CG  . GLN C 1 373 ? 116.841 147.254 169.868 1.00 65.06  ? 373 GLN C CG  1 
ATOM   10351 C CD  . GLN C 1 373 ? 115.761 146.942 168.850 1.00 65.06  ? 373 GLN C CD  1 
ATOM   10352 O OE1 . GLN C 1 373 ? 114.779 146.265 169.154 1.00 65.06  ? 373 GLN C OE1 1 
ATOM   10353 N NE2 . GLN C 1 373 ? 115.943 147.430 167.630 1.00 65.06  ? 373 GLN C NE2 1 
ATOM   10354 N N   . ALA C 1 374 ? 119.834 144.781 170.401 1.00 63.68  ? 374 ALA C N   1 
ATOM   10355 C CA  . ALA C 1 374 ? 121.167 144.809 169.810 1.00 63.68  ? 374 ALA C CA  1 
ATOM   10356 C C   . ALA C 1 374 ? 121.365 143.639 168.853 1.00 63.68  ? 374 ALA C C   1 
ATOM   10357 O O   . ALA C 1 374 ? 121.861 143.814 167.733 1.00 63.68  ? 374 ALA C O   1 
ATOM   10358 C CB  . ALA C 1 374 ? 122.229 144.796 170.909 1.00 63.68  ? 374 ALA C CB  1 
ATOM   10359 N N   . ALA C 1 375 ? 120.957 142.438 169.272 1.00 61.80  ? 375 ALA C N   1 
ATOM   10360 C CA  . ALA C 1 375 ? 121.109 141.266 168.414 1.00 61.80  ? 375 ALA C CA  1 
ATOM   10361 C C   . ALA C 1 375 ? 120.291 141.403 167.137 1.00 61.80  ? 375 ALA C C   1 
ATOM   10362 O O   . ALA C 1 375 ? 120.781 141.100 166.042 1.00 61.80  ? 375 ALA C O   1 
ATOM   10363 C CB  . ALA C 1 375 ? 120.708 140.003 169.174 1.00 61.80  ? 375 ALA C CB  1 
ATOM   10364 N N   . ILE C 1 376 ? 119.044 141.865 167.255 1.00 61.85  ? 376 ILE C N   1 
ATOM   10365 C CA  . ILE C 1 376 ? 118.190 141.985 166.077 1.00 61.85  ? 376 ILE C CA  1 
ATOM   10366 C C   . ILE C 1 376 ? 118.727 143.046 165.123 1.00 61.85  ? 376 ILE C C   1 
ATOM   10367 O O   . ILE C 1 376 ? 118.761 142.841 163.904 1.00 61.85  ? 376 ILE C O   1 
ATOM   10368 C CB  . ILE C 1 376 ? 116.737 142.273 166.493 1.00 61.85  ? 376 ILE C CB  1 
ATOM   10369 C CG1 . ILE C 1 376 ? 116.181 141.101 167.303 1.00 61.85  ? 376 ILE C CG1 1 
ATOM   10370 C CG2 . ILE C 1 376 ? 115.876 142.533 165.270 1.00 61.85  ? 376 ILE C CG2 1 
ATOM   10371 C CD1 . ILE C 1 376 ? 114.684 141.125 167.472 1.00 61.85  ? 376 ILE C CD1 1 
ATOM   10372 N N   . ASP C 1 377 ? 119.161 144.192 165.654 1.00 62.33  ? 377 ASP C N   1 
ATOM   10373 C CA  . ASP C 1 377 ? 119.709 145.238 164.798 1.00 62.33  ? 377 ASP C CA  1 
ATOM   10374 C C   . ASP C 1 377 ? 121.003 144.796 164.130 1.00 62.33  ? 377 ASP C C   1 
ATOM   10375 O O   . ASP C 1 377 ? 121.298 145.225 163.009 1.00 62.33  ? 377 ASP C O   1 
ATOM   10376 C CB  . ASP C 1 377 ? 119.936 146.514 165.605 1.00 62.33  ? 377 ASP C CB  1 
ATOM   10377 C CG  . ASP C 1 377 ? 118.642 147.233 165.931 1.00 62.33  ? 377 ASP C CG  1 
ATOM   10378 O OD1 . ASP C 1 377 ? 117.659 146.553 166.294 1.00 62.33  ? 377 ASP C OD1 1 
ATOM   10379 O OD2 . ASP C 1 377 ? 118.608 148.477 165.823 1.00 62.33  ? 377 ASP C OD2 1 
ATOM   10380 N N   . GLN C 1 378 ? 121.789 143.952 164.799 1.00 58.08  ? 378 GLN C N   1 
ATOM   10381 C CA  . GLN C 1 378 ? 122.976 143.396 164.162 1.00 58.08  ? 378 GLN C CA  1 
ATOM   10382 C C   . GLN C 1 378 ? 122.599 142.438 163.038 1.00 58.08  ? 378 GLN C C   1 
ATOM   10383 O O   . GLN C 1 378 ? 123.205 142.464 161.961 1.00 58.08  ? 378 GLN C O   1 
ATOM   10384 C CB  . GLN C 1 378 ? 123.835 142.691 165.210 1.00 58.08  ? 378 GLN C CB  1 
ATOM   10385 C CG  . GLN C 1 378 ? 124.911 143.562 165.827 1.00 58.08  ? 378 GLN C CG  1 
ATOM   10386 C CD  . GLN C 1 378 ? 125.681 142.845 166.919 1.00 58.08  ? 378 GLN C CD  1 
ATOM   10387 O OE1 . GLN C 1 378 ? 126.776 142.333 166.693 1.00 58.08  ? 378 GLN C OE1 1 
ATOM   10388 N NE2 . GLN C 1 378 ? 125.108 142.808 168.115 1.00 58.08  ? 378 GLN C NE2 1 
ATOM   10389 N N   . ILE C 1 379 ? 121.599 141.586 163.272 1.00 57.00  ? 379 ILE C N   1 
ATOM   10390 C CA  . ILE C 1 379 ? 121.238 140.564 162.293 1.00 57.00  ? 379 ILE C CA  1 
ATOM   10391 C C   . ILE C 1 379 ? 120.546 141.185 161.082 1.00 57.00  ? 379 ILE C C   1 
ATOM   10392 O O   . ILE C 1 379 ? 120.794 140.787 159.938 1.00 57.00  ? 379 ILE C O   1 
ATOM   10393 C CB  . ILE C 1 379 ? 120.372 139.481 162.964 1.00 57.00  ? 379 ILE C CB  1 
ATOM   10394 C CG1 . ILE C 1 379 ? 121.248 138.582 163.839 1.00 57.00  ? 379 ILE C CG1 1 
ATOM   10395 C CG2 . ILE C 1 379 ? 119.628 138.658 161.927 1.00 57.00  ? 379 ILE C CG2 1 
ATOM   10396 C CD1 . ILE C 1 379 ? 120.474 137.632 164.716 1.00 57.00  ? 379 ILE C CD1 1 
ATOM   10397 N N   . ASN C 1 380 ? 119.678 142.167 161.308 1.00 57.91  ? 380 ASN C N   1 
ATOM   10398 C CA  . ASN C 1 380 ? 118.897 142.742 160.220 1.00 57.91  ? 380 ASN C CA  1 
ATOM   10399 C C   . ASN C 1 380 ? 119.781 143.530 159.260 1.00 57.91  ? 380 ASN C C   1 
ATOM   10400 O O   . ASN C 1 380 ? 120.668 144.279 159.678 1.00 57.91  ? 380 ASN C O   1 
ATOM   10401 C CB  . ASN C 1 380 ? 117.799 143.645 160.778 1.00 57.91  ? 380 ASN C CB  1 
ATOM   10402 C CG  . ASN C 1 380 ? 116.493 142.909 160.991 1.00 57.91  ? 380 ASN C CG  1 
ATOM   10403 O OD1 . ASN C 1 380 ? 116.379 141.722 160.685 1.00 57.91  ? 380 ASN C OD1 1 
ATOM   10404 N ND2 . ASN C 1 380 ? 115.497 143.611 161.517 1.00 57.91  ? 380 ASN C ND2 1 
ATOM   10405 N N   . GLY C 1 381 ? 119.529 143.358 157.963 1.00 53.65  ? 381 GLY C N   1 
ATOM   10406 C CA  . GLY C 1 381 ? 120.283 144.067 156.947 1.00 53.65  ? 381 GLY C CA  1 
ATOM   10407 C C   . GLY C 1 381 ? 121.703 143.592 156.755 1.00 53.65  ? 381 GLY C C   1 
ATOM   10408 O O   . GLY C 1 381 ? 122.541 144.355 156.270 1.00 53.65  ? 381 GLY C O   1 
ATOM   10409 N N   . LYS C 1 382 ? 121.999 142.344 157.121 1.00 50.07  ? 382 LYS C N   1 
ATOM   10410 C CA  . LYS C 1 382 ? 123.376 141.862 157.092 1.00 50.07  ? 382 LYS C CA  1 
ATOM   10411 C C   . LYS C 1 382 ? 123.889 141.710 155.664 1.00 50.07  ? 382 LYS C C   1 
ATOM   10412 O O   . LYS C 1 382 ? 124.998 142.149 155.343 1.00 50.07  ? 382 LYS C O   1 
ATOM   10413 C CB  . LYS C 1 382 ? 123.473 140.534 157.844 1.00 50.07  ? 382 LYS C CB  1 
ATOM   10414 C CG  . LYS C 1 382 ? 124.735 140.379 158.670 1.00 50.07  ? 382 LYS C CG  1 
ATOM   10415 C CD  . LYS C 1 382 ? 124.493 139.495 159.880 1.00 50.07  ? 382 LYS C CD  1 
ATOM   10416 C CE  . LYS C 1 382 ? 125.799 138.999 160.466 1.00 50.07  ? 382 LYS C CE  1 
ATOM   10417 N NZ  . LYS C 1 382 ? 126.254 137.750 159.801 1.00 50.07  ? 382 LYS C NZ  1 
ATOM   10418 N N   . LEU C 1 383 ? 123.092 141.093 154.788 1.00 48.71  ? 383 LEU C N   1 
ATOM   10419 C CA  . LEU C 1 383 ? 123.572 140.771 153.448 1.00 48.71  ? 383 LEU C CA  1 
ATOM   10420 C C   . LEU C 1 383 ? 123.656 141.992 152.540 1.00 48.71  ? 383 LEU C C   1 
ATOM   10421 O O   . LEU C 1 383 ? 124.373 141.950 151.536 1.00 48.71  ? 383 LEU C O   1 
ATOM   10422 C CB  . LEU C 1 383 ? 122.678 139.708 152.810 1.00 48.71  ? 383 LEU C CB  1 
ATOM   10423 C CG  . LEU C 1 383 ? 123.364 138.799 151.791 1.00 48.71  ? 383 LEU C CG  1 
ATOM   10424 C CD1 . LEU C 1 383 ? 124.361 137.878 152.474 1.00 48.71  ? 383 LEU C CD1 1 
ATOM   10425 C CD2 . LEU C 1 383 ? 122.339 138.000 151.012 1.00 48.71  ? 383 LEU C CD2 1 
ATOM   10426 N N   . ASN C 1 384 ? 122.952 143.076 152.867 1.00 51.37  ? 384 ASN C N   1 
ATOM   10427 C CA  . ASN C 1 384 ? 123.034 144.282 152.053 1.00 51.37  ? 384 ASN C CA  1 
ATOM   10428 C C   . ASN C 1 384 ? 124.359 145.012 152.226 1.00 51.37  ? 384 ASN C C   1 
ATOM   10429 O O   . ASN C 1 384 ? 124.682 145.884 151.412 1.00 51.37  ? 384 ASN C O   1 
ATOM   10430 C CB  . ASN C 1 384 ? 121.877 145.224 152.389 1.00 51.37  ? 384 ASN C CB  1 
ATOM   10431 C CG  . ASN C 1 384 ? 120.523 144.596 152.135 1.00 51.37  ? 384 ASN C CG  1 
ATOM   10432 O OD1 . ASN C 1 384 ? 120.347 143.833 151.186 1.00 51.37  ? 384 ASN C OD1 1 
ATOM   10433 N ND2 . ASN C 1 384 ? 119.557 144.909 152.990 1.00 51.37  ? 384 ASN C ND2 1 
ATOM   10434 N N   . ARG C 1 385 ? 125.129 144.681 153.264 1.00 49.60  ? 385 ARG C N   1 
ATOM   10435 C CA  . ARG C 1 385 ? 126.396 145.367 153.493 1.00 49.60  ? 385 ARG C CA  1 
ATOM   10436 C C   . ARG C 1 385 ? 127.454 144.968 152.471 1.00 49.60  ? 385 ARG C C   1 
ATOM   10437 O O   . ARG C 1 385 ? 128.338 145.772 152.153 1.00 49.60  ? 385 ARG C O   1 
ATOM   10438 C CB  . ARG C 1 385 ? 126.899 145.081 154.908 1.00 49.60  ? 385 ARG C CB  1 
ATOM   10439 C CG  . ARG C 1 385 ? 126.272 145.951 155.983 1.00 49.60  ? 385 ARG C CG  1 
ATOM   10440 C CD  . ARG C 1 385 ? 126.244 145.237 157.323 1.00 49.60  ? 385 ARG C CD  1 
ATOM   10441 N NE  . ARG C 1 385 ? 125.134 145.684 158.156 1.00 49.60  ? 385 ARG C NE  1 
ATOM   10442 C CZ  . ARG C 1 385 ? 124.620 144.985 159.157 1.00 49.60  ? 385 ARG C CZ  1 
ATOM   10443 N NH1 . ARG C 1 385 ? 125.093 143.793 159.483 1.00 49.60  ? 385 ARG C NH1 1 
ATOM   10444 N NH2 . ARG C 1 385 ? 123.605 145.492 159.848 1.00 49.60  ? 385 ARG C NH2 1 
ATOM   10445 N N   . VAL C 1 386 ? 127.387 143.747 151.951 1.00 46.38  ? 386 VAL C N   1 
ATOM   10446 C CA  . VAL C 1 386 ? 128.414 143.203 151.073 1.00 46.38  ? 386 VAL C CA  1 
ATOM   10447 C C   . VAL C 1 386 ? 127.951 143.170 149.620 1.00 46.38  ? 386 VAL C C   1 
ATOM   10448 O O   . VAL C 1 386 ? 128.681 143.583 148.719 1.00 46.38  ? 386 VAL C O   1 
ATOM   10449 C CB  . VAL C 1 386 ? 128.854 141.800 151.546 1.00 46.38  ? 386 VAL C CB  1 
ATOM   10450 C CG1 . VAL C 1 386 ? 129.813 141.175 150.545 1.00 46.38  ? 386 VAL C CG1 1 
ATOM   10451 C CG2 . VAL C 1 386 ? 129.492 141.885 152.921 1.00 46.38  ? 386 VAL C CG2 1 
ATOM   10452 N N   . ILE C 1 387 ? 126.740 142.689 149.376 1.00 49.09  ? 387 ILE C N   1 
ATOM   10453 C CA  . ILE C 1 387 ? 126.261 142.453 148.020 1.00 49.09  ? 387 ILE C CA  1 
ATOM   10454 C C   . ILE C 1 387 ? 125.314 143.573 147.609 1.00 49.09  ? 387 ILE C C   1 
ATOM   10455 O O   . ILE C 1 387 ? 124.605 144.162 148.433 1.00 49.09  ? 387 ILE C O   1 
ATOM   10456 C CB  . ILE C 1 387 ? 125.596 141.063 147.900 1.00 49.09  ? 387 ILE C CB  1 
ATOM   10457 C CG1 . ILE C 1 387 ? 125.732 140.526 146.475 1.00 49.09  ? 387 ILE C CG1 1 
ATOM   10458 C CG2 . ILE C 1 387 ? 124.137 141.100 148.339 1.00 49.09  ? 387 ILE C CG2 1 
ATOM   10459 C CD1 . ILE C 1 387 ? 125.810 139.020 146.398 1.00 49.09  ? 387 ILE C CD1 1 
ATOM   10460 N N   . GLU C 1 388 ? 125.327 143.885 146.317 1.00 54.70  ? 388 GLU C N   1 
ATOM   10461 C CA  . GLU C 1 388 ? 124.523 144.958 145.755 1.00 54.70  ? 388 GLU C CA  1 
ATOM   10462 C C   . GLU C 1 388 ? 123.075 144.508 145.579 1.00 54.70  ? 388 GLU C C   1 
ATOM   10463 O O   . GLU C 1 388 ? 122.769 143.313 145.533 1.00 54.70  ? 388 GLU C O   1 
ATOM   10464 C CB  . GLU C 1 388 ? 125.103 145.415 144.415 1.00 54.70  ? 388 GLU C CB  1 
ATOM   10465 C CG  . GLU C 1 388 ? 126.622 145.346 144.338 1.00 54.70  ? 388 GLU C CG  1 
ATOM   10466 C CD  . GLU C 1 388 ? 127.126 143.973 143.919 1.00 54.70  ? 388 GLU C CD  1 
ATOM   10467 O OE1 . GLU C 1 388 ? 126.326 143.188 143.369 1.00 54.70  ? 388 GLU C OE1 1 
ATOM   10468 O OE2 . GLU C 1 388 ? 128.317 143.675 144.151 1.00 54.70  ? 388 GLU C OE2 1 
ATOM   10469 N N   . LYS C 1 389 ? 122.177 145.490 145.478 1.00 59.36  ? 389 LYS C N   1 
ATOM   10470 C CA  . LYS C 1 389 ? 120.747 145.189 145.458 1.00 59.36  ? 389 LYS C CA  1 
ATOM   10471 C C   . LYS C 1 389 ? 120.352 144.445 144.186 1.00 59.36  ? 389 LYS C C   1 
ATOM   10472 O O   . LYS C 1 389 ? 119.919 143.288 144.239 1.00 59.36  ? 389 LYS C O   1 
ATOM   10473 C CB  . LYS C 1 389 ? 119.938 146.480 145.602 1.00 59.36  ? 389 LYS C CB  1 
ATOM   10474 C CG  . LYS C 1 389 ? 118.485 146.254 145.994 1.00 59.36  ? 389 LYS C CG  1 
ATOM   10475 C CD  . LYS C 1 389 ? 117.782 147.564 146.312 1.00 59.36  ? 389 LYS C CD  1 
ATOM   10476 C CE  . LYS C 1 389 ? 116.349 147.325 146.761 1.00 59.36  ? 389 LYS C CE  1 
ATOM   10477 N NZ  . LYS C 1 389 ? 115.673 148.587 147.171 1.00 59.36  ? 389 LYS C NZ  1 
ATOM   10478 N N   . THR C 1 390 ? 120.499 145.090 143.032 1.00 54.20  ? 390 THR C N   1 
ATOM   10479 C CA  . THR C 1 390 ? 120.128 144.482 141.760 1.00 54.20  ? 390 THR C CA  1 
ATOM   10480 C C   . THR C 1 390 ? 121.062 144.989 140.675 1.00 54.20  ? 390 THR C C   1 
ATOM   10481 O O   . THR C 1 390 ? 121.268 146.199 140.549 1.00 54.20  ? 390 THR C O   1 
ATOM   10482 C CB  . THR C 1 390 ? 118.673 144.797 141.380 1.00 54.20  ? 390 THR C CB  1 
ATOM   10483 O OG1 . THR C 1 390 ? 118.341 146.130 141.792 1.00 54.20  ? 390 THR C OG1 1 
ATOM   10484 C CG2 . THR C 1 390 ? 117.708 143.803 142.015 1.00 54.20  ? 390 THR C CG2 1 
ATOM   10485 N N   . ASN C 1 391 ? 121.614 144.066 139.895 1.00 45.37  ? 391 ASN C N   1 
ATOM   10486 C CA  . ASN C 1 391 ? 122.423 144.404 138.733 1.00 45.37  ? 391 ASN C CA  1 
ATOM   10487 C C   . ASN C 1 391 ? 121.550 144.299 137.489 1.00 45.37  ? 391 ASN C C   1 
ATOM   10488 O O   . ASN C 1 391 ? 121.001 143.231 137.200 1.00 45.37  ? 391 ASN C O   1 
ATOM   10489 C CB  . ASN C 1 391 ? 123.643 143.487 138.627 1.00 45.37  ? 391 ASN C CB  1 
ATOM   10490 C CG  . ASN C 1 391 ? 123.284 142.016 138.756 1.00 45.37  ? 391 ASN C CG  1 
ATOM   10491 O OD1 . ASN C 1 391 ? 122.793 141.573 139.794 1.00 45.37  ? 391 ASN C OD1 1 
ATOM   10492 N ND2 . ASN C 1 391 ? 123.535 141.252 137.700 1.00 45.37  ? 391 ASN C ND2 1 
ATOM   10493 N N   . GLU C 1 392 ? 121.415 145.408 136.765 1.00 40.95  ? 392 GLU C N   1 
ATOM   10494 C CA  . GLU C 1 392 ? 120.591 145.457 135.564 1.00 40.95  ? 392 GLU C CA  1 
ATOM   10495 C C   . GLU C 1 392 ? 121.463 145.246 134.332 1.00 40.95  ? 392 GLU C C   1 
ATOM   10496 O O   . GLU C 1 392 ? 122.379 146.032 134.072 1.00 40.95  ? 392 GLU C O   1 
ATOM   10497 C CB  . GLU C 1 392 ? 119.853 146.792 135.470 1.00 40.95  ? 392 GLU C CB  1 
ATOM   10498 C CG  . GLU C 1 392 ? 118.434 146.749 135.987 1.00 40.95  ? 392 GLU C CG  1 
ATOM   10499 C CD  . GLU C 1 392 ? 117.634 147.977 135.606 1.00 40.95  ? 392 GLU C CD  1 
ATOM   10500 O OE1 . GLU C 1 392 ? 118.038 149.094 135.991 1.00 40.95  ? 392 GLU C OE1 1 
ATOM   10501 O OE2 . GLU C 1 392 ? 116.598 147.826 134.925 1.00 40.95  ? 392 GLU C OE2 1 
ATOM   10502 N N   . LYS C 1 393 ? 121.174 144.187 133.579 1.00 35.88  ? 393 LYS C N   1 
ATOM   10503 C CA  . LYS C 1 393 ? 121.852 143.889 132.327 1.00 35.88  ? 393 LYS C CA  1 
ATOM   10504 C C   . LYS C 1 393 ? 120.804 143.672 131.246 1.00 35.88  ? 393 LYS C C   1 
ATOM   10505 O O   . LYS C 1 393 ? 119.778 143.034 131.492 1.00 35.88  ? 393 LYS C O   1 
ATOM   10506 C CB  . LYS C 1 393 ? 122.749 142.650 132.455 1.00 35.88  ? 393 LYS C CB  1 
ATOM   10507 C CG  . LYS C 1 393 ? 123.568 142.602 133.734 1.00 35.88  ? 393 LYS C CG  1 
ATOM   10508 C CD  . LYS C 1 393 ? 124.916 143.277 133.564 1.00 35.88  ? 393 LYS C CD  1 
ATOM   10509 C CE  . LYS C 1 393 ? 125.636 143.408 134.896 1.00 35.88  ? 393 LYS C CE  1 
ATOM   10510 N NZ  . LYS C 1 393 ? 126.660 144.486 134.881 1.00 35.88  ? 393 LYS C NZ  1 
ATOM   10511 N N   . PHE C 1 394 ? 121.054 144.211 130.052 1.00 34.60  ? 394 PHE C N   1 
ATOM   10512 C CA  . PHE C 1 394 ? 120.037 144.204 129.007 1.00 34.60  ? 394 PHE C CA  1 
ATOM   10513 C C   . PHE C 1 394 ? 120.419 143.359 127.799 1.00 34.60  ? 394 PHE C C   1 
ATOM   10514 O O   . PHE C 1 394 ? 119.723 142.385 127.500 1.00 34.60  ? 394 PHE C O   1 
ATOM   10515 C CB  . PHE C 1 394 ? 119.739 145.649 128.594 1.00 34.60  ? 394 PHE C CB  1 
ATOM   10516 C CG  . PHE C 1 394 ? 119.206 146.489 129.714 1.00 34.60  ? 394 PHE C CG  1 
ATOM   10517 C CD1 . PHE C 1 394 ? 117.912 146.309 130.172 1.00 34.60  ? 394 PHE C CD1 1 
ATOM   10518 C CD2 . PHE C 1 394 ? 120.003 147.440 130.327 1.00 34.60  ? 394 PHE C CD2 1 
ATOM   10519 C CE1 . PHE C 1 394 ? 117.417 147.073 131.210 1.00 34.60  ? 394 PHE C CE1 1 
ATOM   10520 C CE2 . PHE C 1 394 ? 119.515 148.207 131.365 1.00 34.60  ? 394 PHE C CE2 1 
ATOM   10521 C CZ  . PHE C 1 394 ? 118.219 148.023 131.807 1.00 34.60  ? 394 PHE C CZ  1 
ATOM   10522 N N   . HIS C 1 395 ? 121.513 143.668 127.112 1.00 32.13  ? 395 HIS C N   1 
ATOM   10523 C CA  . HIS C 1 395 ? 121.914 142.931 125.922 1.00 32.13  ? 395 HIS C CA  1 
ATOM   10524 C C   . HIS C 1 395 ? 123.253 142.266 126.190 1.00 32.13  ? 395 HIS C C   1 
ATOM   10525 O O   . HIS C 1 395 ? 124.194 142.919 126.649 1.00 32.13  ? 395 HIS C O   1 
ATOM   10526 C CB  . HIS C 1 395 ? 122.003 143.840 124.694 1.00 32.13  ? 395 HIS C CB  1 
ATOM   10527 C CG  . HIS C 1 395 ? 122.291 143.105 123.422 1.00 32.13  ? 395 HIS C CG  1 
ATOM   10528 N ND1 . HIS C 1 395 ? 121.499 142.076 122.963 1.00 32.13  ? 395 HIS C ND1 1 
ATOM   10529 C CD2 . HIS C 1 395 ? 123.290 143.242 122.518 1.00 32.13  ? 395 HIS C CD2 1 
ATOM   10530 C CE1 . HIS C 1 395 ? 121.993 141.614 121.828 1.00 32.13  ? 395 HIS C CE1 1 
ATOM   10531 N NE2 . HIS C 1 395 ? 123.081 142.304 121.537 1.00 32.13  ? 395 HIS C NE2 1 
ATOM   10532 N N   . GLN C 1 396 ? 123.334 140.972 125.900 1.00 32.35  ? 396 GLN C N   1 
ATOM   10533 C CA  . GLN C 1 396 ? 124.489 140.164 126.262 1.00 32.35  ? 396 GLN C CA  1 
ATOM   10534 C C   . GLN C 1 396 ? 124.810 139.242 125.091 1.00 32.35  ? 396 GLN C C   1 
ATOM   10535 O O   . GLN C 1 396 ? 124.310 139.422 123.977 1.00 32.35  ? 396 GLN C O   1 
ATOM   10536 C CB  . GLN C 1 396 ? 124.218 139.387 127.559 1.00 32.35  ? 396 GLN C CB  1 
ATOM   10537 C CG  . GLN C 1 396 ? 124.100 140.261 128.800 1.00 32.35  ? 396 GLN C CG  1 
ATOM   10538 C CD  . GLN C 1 396 ? 123.333 139.588 129.923 1.00 32.35  ? 396 GLN C CD  1 
ATOM   10539 O OE1 . GLN C 1 396 ? 123.874 138.755 130.647 1.00 32.35  ? 396 GLN C OE1 1 
ATOM   10540 N NE2 . GLN C 1 396 ? 122.064 139.946 130.068 1.00 32.35  ? 396 GLN C NE2 1 
ATOM   10541 N N   . ILE C 1 397 ? 125.654 138.255 125.344 1.00 29.89  ? 397 ILE C N   1 
ATOM   10542 C CA  . ILE C 1 397 ? 126.035 137.286 124.330 1.00 29.89  ? 397 ILE C CA  1 
ATOM   10543 C C   . ILE C 1 397 ? 125.001 136.168 124.283 1.00 29.89  ? 397 ILE C C   1 
ATOM   10544 O O   . ILE C 1 397 ? 124.184 136.000 125.191 1.00 29.89  ? 397 ILE C O   1 
ATOM   10545 C CB  . ILE C 1 397 ? 127.445 136.723 124.598 1.00 29.89  ? 397 ILE C CB  1 
ATOM   10546 C CG1 . ILE C 1 397 ? 127.500 136.067 125.979 1.00 29.89  ? 397 ILE C CG1 1 
ATOM   10547 C CG2 . ILE C 1 397 ? 128.485 137.821 124.483 1.00 29.89  ? 397 ILE C CG2 1 
ATOM   10548 C CD1 . ILE C 1 397 ? 128.680 135.150 126.173 1.00 29.89  ? 397 ILE C CD1 1 
ATOM   10549 N N   . GLU C 1 398 ? 125.033 135.399 123.200 1.00 31.26  ? 398 GLU C N   1 
ATOM   10550 C CA  . GLU C 1 398 ? 124.226 134.190 123.121 1.00 31.26  ? 398 GLU C CA  1 
ATOM   10551 C C   . GLU C 1 398 ? 124.840 133.098 123.987 1.00 31.26  ? 398 GLU C C   1 
ATOM   10552 O O   . GLU C 1 398 ? 126.063 132.988 124.100 1.00 31.26  ? 398 GLU C O   1 
ATOM   10553 C CB  . GLU C 1 398 ? 124.112 133.717 121.671 1.00 31.26  ? 398 GLU C CB  1 
ATOM   10554 C CG  . GLU C 1 398 ? 123.373 134.682 120.763 1.00 31.26  ? 398 GLU C CG  1 
ATOM   10555 C CD  . GLU C 1 398 ? 121.946 134.921 121.209 1.00 31.26  ? 398 GLU C CD  1 
ATOM   10556 O OE1 . GLU C 1 398 ? 121.216 133.932 121.417 1.00 31.26  ? 398 GLU C OE1 1 
ATOM   10557 O OE2 . GLU C 1 398 ? 121.553 136.097 121.357 1.00 31.26  ? 398 GLU C OE2 1 
ATOM   10558 N N   . LYS C 1 399 ? 123.982 132.290 124.604 1.00 30.15  ? 399 LYS C N   1 
ATOM   10559 C CA  . LYS C 1 399 ? 124.435 131.254 125.517 1.00 30.15  ? 399 LYS C CA  1 
ATOM   10560 C C   . LYS C 1 399 ? 123.926 129.863 125.162 1.00 30.15  ? 399 LYS C C   1 
ATOM   10561 O O   . LYS C 1 399 ? 124.293 128.900 125.841 1.00 30.15  ? 399 LYS C O   1 
ATOM   10562 C CB  . LYS C 1 399 ? 124.031 131.607 126.957 1.00 30.15  ? 399 LYS C CB  1 
ATOM   10563 C CG  . LYS C 1 399 ? 124.776 132.813 127.508 1.00 30.15  ? 399 LYS C CG  1 
ATOM   10564 C CD  . LYS C 1 399 ? 124.100 133.402 128.732 1.00 30.15  ? 399 LYS C CD  1 
ATOM   10565 C CE  . LYS C 1 399 ? 124.759 134.711 129.137 1.00 30.15  ? 399 LYS C CE  1 
ATOM   10566 N NZ  . LYS C 1 399 ? 124.133 135.306 130.345 1.00 30.15  ? 399 LYS C NZ  1 
ATOM   10567 N N   . GLU C 1 400 ? 123.099 129.729 124.129 1.00 33.77  ? 400 GLU C N   1 
ATOM   10568 C CA  . GLU C 1 400 ? 122.651 128.439 123.624 1.00 33.77  ? 400 GLU C CA  1 
ATOM   10569 C C   . GLU C 1 400 ? 122.758 128.445 122.107 1.00 33.77  ? 400 GLU C C   1 
ATOM   10570 O O   . GLU C 1 400 ? 122.450 129.450 121.462 1.00 33.77  ? 400 GLU C O   1 
ATOM   10571 C CB  . GLU C 1 400 ? 121.208 128.132 124.051 1.00 33.77  ? 400 GLU C CB  1 
ATOM   10572 C CG  . GLU C 1 400 ? 121.071 127.592 125.464 1.00 33.77  ? 400 GLU C CG  1 
ATOM   10573 C CD  . GLU C 1 400 ? 119.636 127.241 125.818 1.00 33.77  ? 400 GLU C CD  1 
ATOM   10574 O OE1 . GLU C 1 400 ? 118.922 126.696 124.952 1.00 33.77  ? 400 GLU C OE1 1 
ATOM   10575 O OE2 . GLU C 1 400 ? 119.222 127.508 126.965 1.00 33.77  ? 400 GLU C OE2 1 
ATOM   10576 N N   . PHE C 1 401 ? 123.188 127.321 121.539 1.00 32.72  ? 401 PHE C N   1 
ATOM   10577 C CA  . PHE C 1 401 ? 123.467 127.231 120.114 1.00 32.72  ? 401 PHE C CA  1 
ATOM   10578 C C   . PHE C 1 401 ? 122.805 125.997 119.520 1.00 32.72  ? 401 PHE C C   1 
ATOM   10579 O O   . PHE C 1 401 ? 122.648 124.972 120.187 1.00 32.72  ? 401 PHE C O   1 
ATOM   10580 C CB  . PHE C 1 401 ? 124.979 127.197 119.849 1.00 32.72  ? 401 PHE C CB  1 
ATOM   10581 C CG  . PHE C 1 401 ? 125.735 128.310 120.518 1.00 32.72  ? 401 PHE C CG  1 
ATOM   10582 C CD1 . PHE C 1 401 ? 126.224 128.157 121.805 1.00 32.72  ? 401 PHE C CD1 1 
ATOM   10583 C CD2 . PHE C 1 401 ? 125.942 129.513 119.866 1.00 32.72  ? 401 PHE C CD2 1 
ATOM   10584 C CE1 . PHE C 1 401 ? 126.910 129.180 122.426 1.00 32.72  ? 401 PHE C CE1 1 
ATOM   10585 C CE2 . PHE C 1 401 ? 126.631 130.540 120.483 1.00 32.72  ? 401 PHE C CE2 1 
ATOM   10586 C CZ  . PHE C 1 401 ? 127.115 130.372 121.765 1.00 32.72  ? 401 PHE C CZ  1 
ATOM   10587 N N   . SER C 1 402 ? 122.422 126.106 118.248 1.00 37.33  ? 402 SER C N   1 
ATOM   10588 C CA  . SER C 1 402 ? 121.768 125.013 117.541 1.00 37.33  ? 402 SER C CA  1 
ATOM   10589 C C   . SER C 1 402 ? 122.675 124.301 116.544 1.00 37.33  ? 402 SER C C   1 
ATOM   10590 O O   . SER C 1 402 ? 122.393 123.152 116.193 1.00 37.33  ? 402 SER C O   1 
ATOM   10591 C CB  . SER C 1 402 ? 120.520 125.527 116.812 1.00 37.33  ? 402 SER C CB  1 
ATOM   10592 O OG  . SER C 1 402 ? 120.865 126.401 115.754 1.00 37.33  ? 402 SER C OG  1 
ATOM   10593 N N   . GLU C 1 403 ? 123.749 124.942 116.087 1.00 38.66  ? 403 GLU C N   1 
ATOM   10594 C CA  . GLU C 1 403 ? 124.687 124.333 115.156 1.00 38.66  ? 403 GLU C CA  1 
ATOM   10595 C C   . GLU C 1 403 ? 126.098 124.412 115.725 1.00 38.66  ? 403 GLU C C   1 
ATOM   10596 O O   . GLU C 1 403 ? 126.389 125.222 116.608 1.00 38.66  ? 403 GLU C O   1 
ATOM   10597 C CB  . GLU C 1 403 ? 124.648 125.008 113.776 1.00 38.66  ? 403 GLU C CB  1 
ATOM   10598 C CG  . GLU C 1 403 ? 123.367 125.769 113.467 1.00 38.66  ? 403 GLU C CG  1 
ATOM   10599 C CD  . GLU C 1 403 ? 122.208 124.856 113.105 1.00 38.66  ? 403 GLU C CD  1 
ATOM   10600 O OE1 . GLU C 1 403 ? 122.444 123.657 112.847 1.00 38.66  ? 403 GLU C OE1 1 
ATOM   10601 O OE2 . GLU C 1 403 ? 121.057 125.342 113.077 1.00 38.66  ? 403 GLU C OE2 1 
ATOM   10602 N N   . VAL C 1 404 ? 126.973 123.554 115.213 1.00 36.77  ? 404 VAL C N   1 
ATOM   10603 C CA  . VAL C 1 404 ? 128.376 123.542 115.611 1.00 36.77  ? 404 VAL C CA  1 
ATOM   10604 C C   . VAL C 1 404 ? 129.151 124.493 114.710 1.00 36.77  ? 404 VAL C C   1 
ATOM   10605 O O   . VAL C 1 404 ? 128.972 124.493 113.486 1.00 36.77  ? 404 VAL C O   1 
ATOM   10606 C CB  . VAL C 1 404 ? 128.957 122.118 115.556 1.00 36.77  ? 404 VAL C CB  1 
ATOM   10607 C CG1 . VAL C 1 404 ? 128.350 121.259 116.648 1.00 36.77  ? 404 VAL C CG1 1 
ATOM   10608 C CG2 . VAL C 1 404 ? 128.709 121.493 114.204 1.00 36.77  ? 404 VAL C CG2 1 
ATOM   10609 N N   . GLU C 1 405 ? 129.989 125.318 115.311 1.00 34.93  ? 405 GLU C N   1 
ATOM   10610 C CA  . GLU C 1 405 ? 130.714 126.340 114.564 1.00 34.93  ? 405 GLU C CA  1 
ATOM   10611 C C   . GLU C 1 405 ? 132.217 126.300 114.792 1.00 34.93  ? 405 GLU C C   1 
ATOM   10612 O O   . GLU C 1 405 ? 132.978 126.557 113.858 1.00 34.93  ? 405 GLU C O   1 
ATOM   10613 C CB  . GLU C 1 405 ? 130.174 127.727 114.928 1.00 34.93  ? 405 GLU C CB  1 
ATOM   10614 C CG  . GLU C 1 405 ? 128.685 127.889 114.708 1.00 34.93  ? 405 GLU C CG  1 
ATOM   10615 C CD  . GLU C 1 405 ? 128.180 129.247 115.145 1.00 34.93  ? 405 GLU C CD  1 
ATOM   10616 O OE1 . GLU C 1 405 ? 128.467 130.240 114.447 1.00 34.93  ? 405 GLU C OE1 1 
ATOM   10617 O OE2 . GLU C 1 405 ? 127.500 129.322 116.189 1.00 34.93  ? 405 GLU C OE2 1 
ATOM   10618 N N   . GLY C 1 406 ? 132.663 125.994 116.006 1.00 31.50  ? 406 GLY C N   1 
ATOM   10619 C CA  . GLY C 1 406 ? 134.084 125.912 116.277 1.00 31.50  ? 406 GLY C CA  1 
ATOM   10620 C C   . GLY C 1 406 ? 134.626 126.941 117.249 1.00 31.50  ? 406 GLY C C   1 
ATOM   10621 O O   . GLY C 1 406 ? 134.217 126.988 118.411 1.00 31.50  ? 406 GLY C O   1 
ATOM   10622 N N   . ARG C 1 407 ? 135.543 127.781 116.765 1.00 30.25  ? 407 ARG C N   1 
ATOM   10623 C CA  . ARG C 1 407 ? 136.401 128.573 117.645 1.00 30.25  ? 407 ARG C CA  1 
ATOM   10624 C C   . ARG C 1 407 ? 135.605 129.581 118.475 1.00 30.25  ? 407 ARG C C   1 
ATOM   10625 O O   . ARG C 1 407 ? 135.731 129.629 119.707 1.00 30.25  ? 407 ARG C O   1 
ATOM   10626 C CB  . ARG C 1 407 ? 137.462 129.280 116.799 1.00 30.25  ? 407 ARG C CB  1 
ATOM   10627 C CG  . ARG C 1 407 ? 138.782 129.527 117.492 1.00 30.25  ? 407 ARG C CG  1 
ATOM   10628 C CD  . ARG C 1 407 ? 139.775 130.163 116.532 1.00 30.25  ? 407 ARG C CD  1 
ATOM   10629 N NE  . ARG C 1 407 ? 140.895 130.783 117.228 1.00 30.25  ? 407 ARG C NE  1 
ATOM   10630 C CZ  . ARG C 1 407 ? 141.998 131.214 116.635 1.00 30.25  ? 407 ARG C CZ  1 
ATOM   10631 N NH1 . ARG C 1 407 ? 142.160 131.122 115.326 1.00 30.25  ? 407 ARG C NH1 1 
ATOM   10632 N NH2 . ARG C 1 407 ? 142.965 131.750 117.373 1.00 30.25  ? 407 ARG C NH2 1 
ATOM   10633 N N   . ILE C 1 408 ? 134.780 130.398 117.814 1.00 30.02  ? 408 ILE C N   1 
ATOM   10634 C CA  . ILE C 1 408 ? 134.078 131.478 118.505 1.00 30.02  ? 408 ILE C CA  1 
ATOM   10635 C C   . ILE C 1 408 ? 133.054 130.921 119.490 1.00 30.02  ? 408 ILE C C   1 
ATOM   10636 O O   . ILE C 1 408 ? 132.896 131.438 120.605 1.00 30.02  ? 408 ILE C O   1 
ATOM   10637 C CB  . ILE C 1 408 ? 133.425 132.427 117.482 1.00 30.02  ? 408 ILE C CB  1 
ATOM   10638 C CG1 . ILE C 1 408 ? 134.419 132.806 116.383 1.00 30.02  ? 408 ILE C CG1 1 
ATOM   10639 C CG2 . ILE C 1 408 ? 132.903 133.678 118.167 1.00 30.02  ? 408 ILE C CG2 1 
ATOM   10640 C CD1 . ILE C 1 408 ? 135.652 133.530 116.882 1.00 30.02  ? 408 ILE C CD1 1 
ATOM   10641 N N   . GLN C 1 409 ? 132.332 129.871 119.089 1.00 30.74  ? 409 GLN C N   1 
ATOM   10642 C CA  . GLN C 1 409 ? 131.382 129.234 119.995 1.00 30.74  ? 409 GLN C CA  1 
ATOM   10643 C C   . GLN C 1 409 ? 132.091 128.641 121.206 1.00 30.74  ? 409 GLN C C   1 
ATOM   10644 O O   . GLN C 1 409 ? 131.602 128.749 122.340 1.00 30.74  ? 409 GLN C O   1 
ATOM   10645 C CB  . GLN C 1 409 ? 130.590 128.161 119.247 1.00 30.74  ? 409 GLN C CB  1 
ATOM   10646 C CG  . GLN C 1 409 ? 129.391 127.626 120.008 1.00 30.74  ? 409 GLN C CG  1 
ATOM   10647 C CD  . GLN C 1 409 ? 128.606 126.593 119.224 1.00 30.74  ? 409 GLN C CD  1 
ATOM   10648 O OE1 . GLN C 1 409 ? 128.384 125.480 119.694 1.00 30.74  ? 409 GLN C OE1 1 
ATOM   10649 N NE2 . GLN C 1 409 ? 128.177 126.960 118.025 1.00 30.74  ? 409 GLN C NE2 1 
ATOM   10650 N N   . ASP C 1 410 ? 133.251 128.014 120.984 1.00 29.86  ? 410 ASP C N   1 
ATOM   10651 C CA  . ASP C 1 410 ? 134.046 127.498 122.093 1.00 29.86  ? 410 ASP C CA  1 
ATOM   10652 C C   . ASP C 1 410 ? 134.407 128.609 123.069 1.00 29.86  ? 410 ASP C C   1 
ATOM   10653 O O   . ASP C 1 410 ? 134.291 128.437 124.289 1.00 29.86  ? 410 ASP C O   1 
ATOM   10654 C CB  . ASP C 1 410 ? 135.316 126.827 121.567 1.00 29.86  ? 410 ASP C CB  1 
ATOM   10655 C CG  . ASP C 1 410 ? 135.043 125.503 120.878 1.00 29.86  ? 410 ASP C CG  1 
ATOM   10656 O OD1 . ASP C 1 410 ? 133.924 124.972 121.014 1.00 29.86  ? 410 ASP C OD1 1 
ATOM   10657 O OD2 . ASP C 1 410 ? 135.953 124.996 120.190 1.00 29.86  ? 410 ASP C OD2 1 
ATOM   10658 N N   . LEU C 1 411 ? 134.835 129.763 122.549 1.00 27.71  ? 411 LEU C N   1 
ATOM   10659 C CA  . LEU C 1 411 ? 135.220 130.869 123.423 1.00 27.71  ? 411 LEU C CA  1 
ATOM   10660 C C   . LEU C 1 411 ? 134.030 131.407 124.217 1.00 27.71  ? 411 LEU C C   1 
ATOM   10661 O O   . LEU C 1 411 ? 134.153 131.692 125.416 1.00 27.71  ? 411 LEU C O   1 
ATOM   10662 C CB  . LEU C 1 411 ? 135.872 131.977 122.598 1.00 27.71  ? 411 LEU C CB  1 
ATOM   10663 C CG  . LEU C 1 411 ? 136.532 133.126 123.363 1.00 27.71  ? 411 LEU C CG  1 
ATOM   10664 C CD1 . LEU C 1 411 ? 137.469 132.600 124.438 1.00 27.71  ? 411 LEU C CD1 1 
ATOM   10665 C CD2 . LEU C 1 411 ? 137.271 134.039 122.401 1.00 27.71  ? 411 LEU C CD2 1 
ATOM   10666 N N   . GLU C 1 412 ? 132.870 131.551 123.569 1.00 29.00  ? 412 GLU C N   1 
ATOM   10667 C CA  . GLU C 1 412 ? 131.687 132.048 124.272 1.00 29.00  ? 412 GLU C CA  1 
ATOM   10668 C C   . GLU C 1 412 ? 131.259 131.099 125.391 1.00 29.00  ? 412 GLU C C   1 
ATOM   10669 O O   . GLU C 1 412 ? 130.964 131.535 126.519 1.00 29.00  ? 412 GLU C O   1 
ATOM   10670 C CB  . GLU C 1 412 ? 130.546 132.265 123.278 1.00 29.00  ? 412 GLU C CB  1 
ATOM   10671 C CG  . GLU C 1 412 ? 130.760 133.451 122.355 1.00 29.00  ? 412 GLU C CG  1 
ATOM   10672 C CD  . GLU C 1 412 ? 130.012 133.323 121.044 1.00 29.00  ? 412 GLU C CD  1 
ATOM   10673 O OE1 . GLU C 1 412 ? 129.601 132.197 120.698 1.00 29.00  ? 412 GLU C OE1 1 
ATOM   10674 O OE2 . GLU C 1 412 ? 129.835 134.349 120.356 1.00 29.00  ? 412 GLU C OE2 1 
ATOM   10675 N N   . LYS C 1 413 ? 131.240 129.793 125.102 1.00 28.36  ? 413 LYS C N   1 
ATOM   10676 C CA  . LYS C 1 413 ? 130.899 128.814 126.129 1.00 28.36  ? 413 LYS C CA  1 
ATOM   10677 C C   . LYS C 1 413 ? 131.895 128.847 127.282 1.00 28.36  ? 413 LYS C C   1 
ATOM   10678 O O   . LYS C 1 413 ? 131.504 128.763 128.454 1.00 28.36  ? 413 LYS C O   1 
ATOM   10679 C CB  . LYS C 1 413 ? 130.834 127.414 125.518 1.00 28.36  ? 413 LYS C CB  1 
ATOM   10680 C CG  . LYS C 1 413 ? 129.566 127.142 124.731 1.00 28.36  ? 413 LYS C CG  1 
ATOM   10681 C CD  . LYS C 1 413 ? 129.698 125.886 123.885 1.00 28.36  ? 413 LYS C CD  1 
ATOM   10682 C CE  . LYS C 1 413 ? 128.352 125.428 123.362 1.00 28.36  ? 413 LYS C CE  1 
ATOM   10683 N NZ  . LYS C 1 413 ? 128.383 124.017 122.889 1.00 28.36  ? 413 LYS C NZ  1 
ATOM   10684 N N   . TYR C 1 414 ? 133.189 128.972 126.968 1.00 26.15  ? 414 TYR C N   1 
ATOM   10685 C CA  . TYR C 1 414 ? 134.209 129.015 128.011 1.00 26.15  ? 414 TYR C CA  1 
ATOM   10686 C C   . TYR C 1 414 ? 134.017 130.221 128.924 1.00 26.15  ? 414 TYR C C   1 
ATOM   10687 O O   . TYR C 1 414 ? 134.119 130.103 130.153 1.00 26.15  ? 414 TYR C O   1 
ATOM   10688 C CB  . TYR C 1 414 ? 135.595 129.034 127.370 1.00 26.15  ? 414 TYR C CB  1 
ATOM   10689 C CG  . TYR C 1 414 ? 136.747 128.851 128.329 1.00 26.15  ? 414 TYR C CG  1 
ATOM   10690 C CD1 . TYR C 1 414 ? 137.029 127.609 128.878 1.00 26.15  ? 414 TYR C CD1 1 
ATOM   10691 C CD2 . TYR C 1 414 ? 137.562 129.920 128.674 1.00 26.15  ? 414 TYR C CD2 1 
ATOM   10692 C CE1 . TYR C 1 414 ? 138.084 127.438 129.747 1.00 26.15  ? 414 TYR C CE1 1 
ATOM   10693 C CE2 . TYR C 1 414 ? 138.618 129.759 129.542 1.00 26.15  ? 414 TYR C CE2 1 
ATOM   10694 C CZ  . TYR C 1 414 ? 138.876 128.516 130.075 1.00 26.15  ? 414 TYR C CZ  1 
ATOM   10695 O OH  . TYR C 1 414 ? 139.928 128.350 130.940 1.00 26.15  ? 414 TYR C OH  1 
ATOM   10696 N N   . VAL C 1 415 ? 133.726 131.386 128.337 1.00 26.04  ? 415 VAL C N   1 
ATOM   10697 C CA  . VAL C 1 415 ? 133.528 132.599 129.130 1.00 26.04  ? 415 VAL C CA  1 
ATOM   10698 C C   . VAL C 1 415 ? 132.349 132.426 130.082 1.00 26.04  ? 415 VAL C C   1 
ATOM   10699 O O   . VAL C 1 415 ? 132.443 132.721 131.287 1.00 26.04  ? 415 VAL C O   1 
ATOM   10700 C CB  . VAL C 1 415 ? 133.336 133.814 128.202 1.00 26.04  ? 415 VAL C CB  1 
ATOM   10701 C CG1 . VAL C 1 415 ? 132.730 134.987 128.957 1.00 26.04  ? 415 VAL C CG1 1 
ATOM   10702 C CG2 . VAL C 1 415 ? 134.655 134.210 127.550 1.00 26.04  ? 415 VAL C CG2 1 
ATOM   10703 N N   . GLU C 1 416 ? 131.224 131.920 129.560 1.00 27.42  ? 416 GLU C N   1 
ATOM   10704 C CA  . GLU C 1 416 ? 130.044 131.759 130.407 1.00 27.42  ? 416 GLU C CA  1 
ATOM   10705 C C   . GLU C 1 416 ? 130.299 130.768 131.541 1.00 27.42  ? 416 GLU C C   1 
ATOM   10706 O O   . GLU C 1 416 ? 129.916 131.016 132.696 1.00 27.42  ? 416 GLU C O   1 
ATOM   10707 C CB  . GLU C 1 416 ? 128.846 131.326 129.562 1.00 27.42  ? 416 GLU C CB  1 
ATOM   10708 C CG  . GLU C 1 416 ? 127.512 131.340 130.297 1.00 27.42  ? 416 GLU C CG  1 
ATOM   10709 C CD  . GLU C 1 416 ? 127.219 132.663 130.988 1.00 27.42  ? 416 GLU C CD  1 
ATOM   10710 O OE1 . GLU C 1 416 ? 127.613 133.723 130.462 1.00 27.42  ? 416 GLU C OE1 1 
ATOM   10711 O OE2 . GLU C 1 416 ? 126.585 132.643 132.060 1.00 27.42  ? 416 GLU C OE2 1 
ATOM   10712 N N   . ASP C 1 417 ? 130.958 129.646 131.235 1.00 26.94  ? 417 ASP C N   1 
ATOM   10713 C CA  . ASP C 1 417 ? 131.246 128.649 132.263 1.00 26.94  ? 417 ASP C CA  1 
ATOM   10714 C C   . ASP C 1 417 ? 132.143 129.214 133.361 1.00 26.94  ? 417 ASP C C   1 
ATOM   10715 O O   . ASP C 1 417 ? 131.903 128.979 134.557 1.00 26.94  ? 417 ASP C O   1 
ATOM   10716 C CB  . ASP C 1 417 ? 131.891 127.423 131.621 1.00 26.94  ? 417 ASP C CB  1 
ATOM   10717 C CG  . ASP C 1 417 ? 131.890 126.223 132.535 1.00 26.94  ? 417 ASP C CG  1 
ATOM   10718 O OD1 . ASP C 1 417 ? 130.792 125.756 132.900 1.00 26.94  ? 417 ASP C OD1 1 
ATOM   10719 O OD2 . ASP C 1 417 ? 132.988 125.748 132.890 1.00 26.94  ? 417 ASP C OD2 1 
ATOM   10720 N N   . THR C 1 418 ? 133.180 129.965 132.975 1.00 25.07  ? 418 THR C N   1 
ATOM   10721 C CA  . THR C 1 418 ? 134.074 130.567 133.960 1.00 25.07  ? 418 THR C CA  1 
ATOM   10722 C C   . THR C 1 418 ? 133.311 131.499 134.896 1.00 25.07  ? 418 THR C C   1 
ATOM   10723 O O   . THR C 1 418 ? 133.469 131.441 136.129 1.00 25.07  ? 418 THR C O   1 
ATOM   10724 C CB  . THR C 1 418 ? 135.196 131.322 133.242 1.00 25.07  ? 418 THR C CB  1 
ATOM   10725 O OG1 . THR C 1 418 ? 135.991 130.400 132.488 1.00 25.07  ? 418 THR C OG1 1 
ATOM   10726 C CG2 . THR C 1 418 ? 136.082 132.054 134.236 1.00 25.07  ? 418 THR C CG2 1 
ATOM   10727 N N   . LYS C 1 419 ? 132.461 132.357 134.324 1.00 24.05  ? 419 LYS C N   1 
ATOM   10728 C CA  . LYS C 1 419 ? 131.699 133.296 135.143 1.00 24.05  ? 419 LYS C CA  1 
ATOM   10729 C C   . LYS C 1 419 ? 130.798 132.563 136.135 1.00 24.05  ? 419 LYS C C   1 
ATOM   10730 O O   . LYS C 1 419 ? 130.739 132.917 137.326 1.00 24.05  ? 419 LYS C O   1 
ATOM   10731 C CB  . LYS C 1 419 ? 130.882 134.217 134.237 1.00 24.05  ? 419 LYS C CB  1 
ATOM   10732 C CG  . LYS C 1 419 ? 129.910 135.129 134.950 1.00 24.05  ? 419 LYS C CG  1 
ATOM   10733 C CD  . LYS C 1 419 ? 129.099 135.917 133.942 1.00 24.05  ? 419 LYS C CD  1 
ATOM   10734 C CE  . LYS C 1 419 ? 128.485 137.157 134.556 1.00 24.05  ? 419 LYS C CE  1 
ATOM   10735 N NZ  . LYS C 1 419 ? 127.021 137.213 134.330 1.00 24.05  ? 419 LYS C NZ  1 
ATOM   10736 N N   . VAL C 1 420 ? 130.098 131.525 135.662 1.00 23.64  ? 420 VAL C N   1 
ATOM   10737 C CA  . VAL C 1 420 ? 129.183 130.789 136.533 1.00 23.64  ? 420 VAL C CA  1 
ATOM   10738 C C   . VAL C 1 420 ? 129.938 130.148 137.693 1.00 23.64  ? 420 VAL C C   1 
ATOM   10739 O O   . VAL C 1 420 ? 129.500 130.214 138.851 1.00 23.64  ? 420 VAL C O   1 
ATOM   10740 C CB  . VAL C 1 420 ? 128.392 129.745 135.722 1.00 23.64  ? 420 VAL C CB  1 
ATOM   10741 C CG1 . VAL C 1 420 ? 127.660 128.792 136.648 1.00 23.64  ? 420 VAL C CG1 1 
ATOM   10742 C CG2 . VAL C 1 420 ? 127.412 130.433 134.792 1.00 23.64  ? 420 VAL C CG2 1 
ATOM   10743 N N   . ASP C 1 421 ? 131.082 129.519 137.405 1.00 25.90  ? 421 ASP C N   1 
ATOM   10744 C CA  . ASP C 1 421 ? 131.840 128.867 138.470 1.00 25.90  ? 421 ASP C CA  1 
ATOM   10745 C C   . ASP C 1 421 ? 132.296 129.870 139.528 1.00 25.90  ? 421 ASP C C   1 
ATOM   10746 O O   . ASP C 1 421 ? 132.159 129.620 140.739 1.00 25.90  ? 421 ASP C O   1 
ATOM   10747 C CB  . ASP C 1 421 ? 133.036 128.123 137.881 1.00 25.90  ? 421 ASP C CB  1 
ATOM   10748 C CG  . ASP C 1 421 ? 132.641 126.817 137.220 1.00 25.90  ? 421 ASP C CG  1 
ATOM   10749 O OD1 . ASP C 1 421 ? 131.534 126.316 137.501 1.00 25.90  ? 421 ASP C OD1 1 
ATOM   10750 O OD2 . ASP C 1 421 ? 133.439 126.288 136.420 1.00 25.90  ? 421 ASP C OD2 1 
ATOM   10751 N N   . LEU C 1 422 ? 132.823 131.019 139.093 1.00 22.83  ? 422 LEU C N   1 
ATOM   10752 C CA  . LEU C 1 422 ? 133.321 131.991 140.065 1.00 22.83  ? 422 LEU C CA  1 
ATOM   10753 C C   . LEU C 1 422 ? 132.194 132.537 140.942 1.00 22.83  ? 422 LEU C C   1 
ATOM   10754 O O   . LEU C 1 422 ? 132.356 132.665 142.167 1.00 22.83  ? 422 LEU C O   1 
ATOM   10755 C CB  . LEU C 1 422 ? 134.069 133.118 139.351 1.00 22.83  ? 422 LEU C CB  1 
ATOM   10756 C CG  . LEU C 1 422 ? 135.485 132.733 138.903 1.00 22.83  ? 422 LEU C CG  1 
ATOM   10757 C CD1 . LEU C 1 422 ? 135.977 133.603 137.756 1.00 22.83  ? 422 LEU C CD1 1 
ATOM   10758 C CD2 . LEU C 1 422 ? 136.466 132.774 140.068 1.00 22.83  ? 422 LEU C CD2 1 
ATOM   10759 N N   . TRP C 1 423 ? 131.030 132.830 140.350 1.00 22.55  ? 423 TRP C N   1 
ATOM   10760 C CA  . TRP C 1 423 ? 129.943 133.365 141.170 1.00 22.55  ? 423 TRP C CA  1 
ATOM   10761 C C   . TRP C 1 423 ? 129.365 132.316 142.123 1.00 22.55  ? 423 TRP C C   1 
ATOM   10762 O O   . TRP C 1 423 ? 128.979 132.655 143.252 1.00 22.55  ? 423 TRP C O   1 
ATOM   10763 C CB  . TRP C 1 423 ? 128.847 133.966 140.289 1.00 22.55  ? 423 TRP C CB  1 
ATOM   10764 C CG  . TRP C 1 423 ? 129.113 135.403 139.929 1.00 22.55  ? 423 TRP C CG  1 
ATOM   10765 C CD1 . TRP C 1 423 ? 129.343 135.904 138.684 1.00 22.55  ? 423 TRP C CD1 1 
ATOM   10766 C CD2 . TRP C 1 423 ? 129.195 136.517 140.830 1.00 22.55  ? 423 TRP C CD2 1 
ATOM   10767 N NE1 . TRP C 1 423 ? 129.556 137.256 138.749 1.00 22.55  ? 423 TRP C NE1 1 
ATOM   10768 C CE2 . TRP C 1 423 ? 129.469 137.659 140.054 1.00 22.55  ? 423 TRP C CE2 1 
ATOM   10769 C CE3 . TRP C 1 423 ? 129.058 136.659 142.214 1.00 22.55  ? 423 TRP C CE3 1 
ATOM   10770 C CZ2 . TRP C 1 423 ? 129.612 138.926 140.616 1.00 22.55  ? 423 TRP C CZ2 1 
ATOM   10771 C CZ3 . TRP C 1 423 ? 129.200 137.918 142.770 1.00 22.55  ? 423 TRP C CZ3 1 
ATOM   10772 C CH2 . TRP C 1 423 ? 129.474 139.035 141.973 1.00 22.55  ? 423 TRP C CH2 1 
ATOM   10773 N N   . SER C 1 424 ? 129.308 131.045 141.708 1.00 24.30  ? 424 SER C N   1 
ATOM   10774 C CA  . SER C 1 424 ? 128.862 130.002 142.631 1.00 24.30  ? 424 SER C CA  1 
ATOM   10775 C C   . SER C 1 424 ? 129.787 129.899 143.839 1.00 24.30  ? 424 SER C C   1 
ATOM   10776 O O   . SER C 1 424 ? 129.322 129.780 144.987 1.00 24.30  ? 424 SER C O   1 
ATOM   10777 C CB  . SER C 1 424 ? 128.779 128.656 141.910 1.00 24.30  ? 424 SER C CB  1 
ATOM   10778 O OG  . SER C 1 424 ? 127.894 128.715 140.810 1.00 24.30  ? 424 SER C OG  1 
ATOM   10779 N N   . TYR C 1 425 ? 131.104 129.948 143.600 1.00 25.20  ? 425 TYR C N   1 
ATOM   10780 C CA  . TYR C 1 425 ? 132.044 129.923 144.718 1.00 25.20  ? 425 TYR C CA  1 
ATOM   10781 C C   . TYR C 1 425 ? 131.818 131.109 145.652 1.00 25.20  ? 425 TYR C C   1 
ATOM   10782 O O   . TYR C 1 425 ? 131.818 130.952 146.885 1.00 25.20  ? 425 TYR C O   1 
ATOM   10783 C CB  . TYR C 1 425 ? 133.484 129.909 144.200 1.00 25.20  ? 425 TYR C CB  1 
ATOM   10784 C CG  . TYR C 1 425 ? 134.531 130.102 145.278 1.00 25.20  ? 425 TYR C CG  1 
ATOM   10785 C CD1 . TYR C 1 425 ? 135.010 129.027 146.011 1.00 25.20  ? 425 TYR C CD1 1 
ATOM   10786 C CD2 . TYR C 1 425 ? 135.046 131.362 145.556 1.00 25.20  ? 425 TYR C CD2 1 
ATOM   10787 C CE1 . TYR C 1 425 ? 135.960 129.200 146.995 1.00 25.20  ? 425 TYR C CE1 1 
ATOM   10788 C CE2 . TYR C 1 425 ? 135.994 131.545 146.539 1.00 25.20  ? 425 TYR C CE2 1 
ATOM   10789 C CZ  . TYR C 1 425 ? 136.450 130.461 147.253 1.00 25.20  ? 425 TYR C CZ  1 
ATOM   10790 O OH  . TYR C 1 425 ? 137.398 130.638 148.231 1.00 25.20  ? 425 TYR C OH  1 
ATOM   10791 N N   . ASN C 1 426 ? 131.632 132.304 145.080 1.00 24.72  ? 426 ASN C N   1 
ATOM   10792 C CA  . ASN C 1 426 ? 131.378 133.488 145.898 1.00 24.72  ? 426 ASN C CA  1 
ATOM   10793 C C   . ASN C 1 426 ? 130.164 133.289 146.800 1.00 24.72  ? 426 ASN C C   1 
ATOM   10794 O O   . ASN C 1 426 ? 130.212 133.592 147.999 1.00 24.72  ? 426 ASN C O   1 
ATOM   10795 C CB  . ASN C 1 426 ? 131.182 134.715 145.007 1.00 24.72  ? 426 ASN C CB  1 
ATOM   10796 C CG  . ASN C 1 426 ? 132.490 135.323 144.548 1.00 24.72  ? 426 ASN C CG  1 
ATOM   10797 O OD1 . ASN C 1 426 ? 133.544 135.069 145.125 1.00 24.72  ? 426 ASN C OD1 1 
ATOM   10798 N ND2 . ASN C 1 426 ? 132.425 136.139 143.507 1.00 24.72  ? 426 ASN C ND2 1 
ATOM   10799 N N   . ALA C 1 427 ? 129.065 132.780 146.237 1.00 27.25  ? 427 ALA C N   1 
ATOM   10800 C CA  . ALA C 1 427 ? 127.843 132.616 147.023 1.00 27.25  ? 427 ALA C CA  1 
ATOM   10801 C C   . ALA C 1 427 ? 128.049 131.639 148.178 1.00 27.25  ? 427 ALA C C   1 
ATOM   10802 O O   . ALA C 1 427 ? 127.640 131.907 149.321 1.00 27.25  ? 427 ALA C O   1 
ATOM   10803 C CB  . ALA C 1 427 ? 126.698 132.154 146.122 1.00 27.25  ? 427 ALA C CB  1 
ATOM   10804 N N   . GLU C 1 428 ? 128.693 130.500 147.900 1.00 31.15  ? 428 GLU C N   1 
ATOM   10805 C CA  . GLU C 1 428 ? 128.927 129.512 148.954 1.00 31.15  ? 428 GLU C CA  1 
ATOM   10806 C C   . GLU C 1 428 ? 129.749 130.106 150.099 1.00 31.15  ? 428 GLU C C   1 
ATOM   10807 O O   . GLU C 1 428 ? 129.372 130.001 151.282 1.00 31.15  ? 428 GLU C O   1 
ATOM   10808 C CB  . GLU C 1 428 ? 129.626 128.285 148.367 1.00 31.15  ? 428 GLU C CB  1 
ATOM   10809 C CG  . GLU C 1 428 ? 129.684 127.079 149.289 1.00 31.15  ? 428 GLU C CG  1 
ATOM   10810 C CD  . GLU C 1 428 ? 128.319 126.465 149.541 1.00 31.15  ? 428 GLU C CD  1 
ATOM   10811 O OE1 . GLU C 1 428 ? 127.766 125.839 148.614 1.00 31.15  ? 428 GLU C OE1 1 
ATOM   10812 O OE2 . GLU C 1 428 ? 127.800 126.605 150.668 1.00 31.15  ? 428 GLU C OE2 1 
ATOM   10813 N N   . LEU C 1 429 ? 130.868 130.757 149.760 1.00 30.42  ? 429 LEU C N   1 
ATOM   10814 C CA  . LEU C 1 429 ? 131.732 131.309 150.798 1.00 30.42  ? 429 LEU C CA  1 
ATOM   10815 C C   . LEU C 1 429 ? 131.015 132.385 151.606 1.00 30.42  ? 429 LEU C C   1 
ATOM   10816 O O   . LEU C 1 429 ? 131.152 132.443 152.838 1.00 30.42  ? 429 LEU C O   1 
ATOM   10817 C CB  . LEU C 1 429 ? 133.014 131.866 150.179 1.00 30.42  ? 429 LEU C CB  1 
ATOM   10818 C CG  . LEU C 1 429 ? 133.995 132.527 151.152 1.00 30.42  ? 429 LEU C CG  1 
ATOM   10819 C CD1 . LEU C 1 429 ? 134.529 131.512 152.150 1.00 30.42  ? 429 LEU C CD1 1 
ATOM   10820 C CD2 . LEU C 1 429 ? 135.135 133.203 150.411 1.00 30.42  ? 429 LEU C CD2 1 
ATOM   10821 N N   . LEU C 1 430 ? 130.250 133.249 150.933 1.00 31.66  ? 430 LEU C N   1 
ATOM   10822 C CA  . LEU C 1 430 ? 129.566 134.324 151.640 1.00 31.66  ? 430 LEU C CA  1 
ATOM   10823 C C   . LEU C 1 430 ? 128.563 133.775 152.645 1.00 31.66  ? 430 LEU C C   1 
ATOM   10824 O O   . LEU C 1 430 ? 128.495 134.253 153.787 1.00 31.66  ? 430 LEU C O   1 
ATOM   10825 C CB  . LEU C 1 430 ? 128.873 135.251 150.643 1.00 31.66  ? 430 LEU C CB  1 
ATOM   10826 C CG  . LEU C 1 430 ? 128.041 136.381 151.251 1.00 31.66  ? 430 LEU C CG  1 
ATOM   10827 C CD1 . LEU C 1 430 ? 128.921 137.328 152.050 1.00 31.66  ? 430 LEU C CD1 1 
ATOM   10828 C CD2 . LEU C 1 430 ? 127.288 137.132 150.172 1.00 31.66  ? 430 LEU C CD2 1 
ATOM   10829 N N   . VAL C 1 431 ? 127.784 132.764 152.246 1.00 32.97  ? 431 VAL C N   1 
ATOM   10830 C CA  . VAL C 1 431 ? 126.807 132.201 153.177 1.00 32.97  ? 431 VAL C CA  1 
ATOM   10831 C C   . VAL C 1 431 ? 127.508 131.603 154.393 1.00 32.97  ? 431 VAL C C   1 
ATOM   10832 O O   . VAL C 1 431 ? 127.097 131.834 155.542 1.00 32.97  ? 431 VAL C O   1 
ATOM   10833 C CB  . VAL C 1 431 ? 125.912 131.170 152.466 1.00 32.97  ? 431 VAL C CB  1 
ATOM   10834 C CG1 . VAL C 1 431 ? 125.118 130.363 153.480 1.00 32.97  ? 431 VAL C CG1 1 
ATOM   10835 C CG2 . VAL C 1 431 ? 124.972 131.868 151.502 1.00 32.97  ? 431 VAL C CG2 1 
ATOM   10836 N N   . ALA C 1 432 ? 128.587 130.843 154.166 1.00 35.69  ? 432 ALA C N   1 
ATOM   10837 C CA  . ALA C 1 432 ? 129.272 130.217 155.299 1.00 35.69  ? 432 ALA C CA  1 
ATOM   10838 C C   . ALA C 1 432 ? 129.827 131.261 156.269 1.00 35.69  ? 432 ALA C C   1 
ATOM   10839 O O   . ALA C 1 432 ? 129.659 131.140 157.495 1.00 35.69  ? 432 ALA C O   1 
ATOM   10840 C CB  . ALA C 1 432 ? 130.386 129.299 154.799 1.00 35.69  ? 432 ALA C CB  1 
ATOM   10841 N N   . LEU C 1 433 ? 130.468 132.306 155.736 1.00 37.12  ? 433 LEU C N   1 
ATOM   10842 C CA  . LEU C 1 433 ? 131.045 133.347 156.585 1.00 37.12  ? 433 LEU C CA  1 
ATOM   10843 C C   . LEU C 1 433 ? 129.972 134.068 157.396 1.00 37.12  ? 433 LEU C C   1 
ATOM   10844 O O   . LEU C 1 433 ? 130.134 134.300 158.606 1.00 37.12  ? 433 LEU C O   1 
ATOM   10845 C CB  . LEU C 1 433 ? 131.814 134.346 155.723 1.00 37.12  ? 433 LEU C CB  1 
ATOM   10846 C CG  . LEU C 1 433 ? 133.329 134.202 155.637 1.00 37.12  ? 433 LEU C CG  1 
ATOM   10847 C CD1 . LEU C 1 433 ? 133.894 135.274 154.722 1.00 37.12  ? 433 LEU C CD1 1 
ATOM   10848 C CD2 . LEU C 1 433 ? 133.950 134.290 157.017 1.00 37.12  ? 433 LEU C CD2 1 
ATOM   10849 N N   . GLU C 1 434 ? 128.869 134.441 156.741 1.00 39.97  ? 434 GLU C N   1 
ATOM   10850 C CA  . GLU C 1 434 ? 127.819 135.174 157.439 1.00 39.97  ? 434 GLU C CA  1 
ATOM   10851 C C   . GLU C 1 434 ? 127.209 134.336 158.557 1.00 39.97  ? 434 GLU C C   1 
ATOM   10852 O O   . GLU C 1 434 ? 126.947 134.849 159.652 1.00 39.97  ? 434 GLU C O   1 
ATOM   10853 C CB  . GLU C 1 434 ? 126.743 135.625 156.452 1.00 39.97  ? 434 GLU C CB  1 
ATOM   10854 C CG  . GLU C 1 434 ? 127.226 136.643 155.433 1.00 39.97  ? 434 GLU C CG  1 
ATOM   10855 C CD  . GLU C 1 434 ? 127.164 138.064 155.948 1.00 39.97  ? 434 GLU C CD  1 
ATOM   10856 O OE1 . GLU C 1 434 ? 126.300 138.351 156.800 1.00 39.97  ? 434 GLU C OE1 1 
ATOM   10857 O OE2 . GLU C 1 434 ? 127.976 138.897 155.501 1.00 39.97  ? 434 GLU C OE2 1 
ATOM   10858 N N   . ASN C 1 435 ? 126.980 133.043 158.303 1.00 37.97  ? 435 ASN C N   1 
ATOM   10859 C CA  . ASN C 1 435 ? 126.422 132.187 159.347 1.00 37.97  ? 435 ASN C CA  1 
ATOM   10860 C C   . ASN C 1 435 ? 127.366 132.079 160.540 1.00 37.97  ? 435 ASN C C   1 
ATOM   10861 O O   . ASN C 1 435 ? 126.929 132.154 161.703 1.00 37.97  ? 435 ASN C O   1 
ATOM   10862 C CB  . ASN C 1 435 ? 126.113 130.804 158.778 1.00 37.97  ? 435 ASN C CB  1 
ATOM   10863 C CG  . ASN C 1 435 ? 124.880 130.797 157.901 1.00 37.97  ? 435 ASN C CG  1 
ATOM   10864 O OD1 . ASN C 1 435 ? 124.100 131.746 157.897 1.00 37.97  ? 435 ASN C OD1 1 
ATOM   10865 N ND2 . ASN C 1 435 ? 124.699 129.722 157.150 1.00 37.97  ? 435 ASN C ND2 1 
ATOM   10866 N N   . GLN C 1 436 ? 128.665 131.906 160.270 1.00 42.14  ? 436 GLN C N   1 
ATOM   10867 C CA  . GLN C 1 436 ? 129.647 131.857 161.351 1.00 42.14  ? 436 GLN C CA  1 
ATOM   10868 C C   . GLN C 1 436 ? 129.569 133.107 162.222 1.00 42.14  ? 436 GLN C C   1 
ATOM   10869 O O   . GLN C 1 436 ? 129.485 133.022 163.458 1.00 42.14  ? 436 GLN C O   1 
ATOM   10870 C CB  . GLN C 1 436 ? 131.049 131.696 160.764 1.00 42.14  ? 436 GLN C CB  1 
ATOM   10871 C CG  . GLN C 1 436 ? 132.170 131.731 161.787 1.00 42.14  ? 436 GLN C CG  1 
ATOM   10872 C CD  . GLN C 1 436 ? 132.415 130.383 162.431 1.00 42.14  ? 436 GLN C CD  1 
ATOM   10873 O OE1 . GLN C 1 436 ? 132.172 129.341 161.827 1.00 42.14  ? 436 GLN C OE1 1 
ATOM   10874 N NE2 . GLN C 1 436 ? 132.897 130.397 163.665 1.00 42.14  ? 436 GLN C NE2 1 
ATOM   10875 N N   . HIS C 1 437 ? 129.573 134.283 161.588 1.00 43.94  ? 437 HIS C N   1 
ATOM   10876 C CA  . HIS C 1 437 ? 129.586 135.515 162.372 1.00 43.94  ? 437 HIS C CA  1 
ATOM   10877 C C   . HIS C 1 437 ? 128.280 135.726 163.133 1.00 43.94  ? 437 HIS C C   1 
ATOM   10878 O O   . HIS C 1 437 ? 128.301 136.249 164.253 1.00 43.94  ? 437 HIS C O   1 
ATOM   10879 C CB  . HIS C 1 437 ? 129.900 136.710 161.476 1.00 43.94  ? 437 HIS C CB  1 
ATOM   10880 C CG  . HIS C 1 437 ? 131.367 136.919 161.259 1.00 43.94  ? 437 HIS C CG  1 
ATOM   10881 N ND1 . HIS C 1 437 ? 132.150 137.647 162.128 1.00 43.94  ? 437 HIS C ND1 1 
ATOM   10882 C CD2 . HIS C 1 437 ? 132.197 136.476 160.287 1.00 43.94  ? 437 HIS C CD2 1 
ATOM   10883 C CE1 . HIS C 1 437 ? 133.397 137.652 161.695 1.00 43.94  ? 437 HIS C CE1 1 
ATOM   10884 N NE2 . HIS C 1 437 ? 133.453 136.948 160.579 1.00 43.94  ? 437 HIS C NE2 1 
ATOM   10885 N N   . THR C 1 438 ? 127.143 135.316 162.563 1.00 45.43  ? 438 THR C N   1 
ATOM   10886 C CA  . THR C 1 438 ? 125.873 135.449 163.275 1.00 45.43  ? 438 THR C CA  1 
ATOM   10887 C C   . THR C 1 438 ? 125.862 134.608 164.550 1.00 45.43  ? 438 THR C C   1 
ATOM   10888 O O   . THR C 1 438 ? 125.464 135.086 165.629 1.00 45.43  ? 438 THR C O   1 
ATOM   10889 C CB  . THR C 1 438 ? 124.717 135.050 162.357 1.00 45.43  ? 438 THR C CB  1 
ATOM   10890 O OG1 . THR C 1 438 ? 124.591 136.009 161.303 1.00 45.43  ? 438 THR C OG1 1 
ATOM   10891 C CG2 . THR C 1 438 ? 123.411 134.981 163.130 1.00 45.43  ? 438 THR C CG2 1 
ATOM   10892 N N   . ILE C 1 439 ? 126.306 133.352 164.447 1.00 47.54  ? 439 ILE C N   1 
ATOM   10893 C CA  . ILE C 1 439 ? 126.347 132.489 165.627 1.00 47.54  ? 439 ILE C CA  1 
ATOM   10894 C C   . ILE C 1 439 ? 127.266 133.087 166.688 1.00 47.54  ? 439 ILE C C   1 
ATOM   10895 O O   . ILE C 1 439 ? 126.922 133.149 167.882 1.00 47.54  ? 439 ILE C O   1 
ATOM   10896 C CB  . ILE C 1 439 ? 126.784 131.066 165.237 1.00 47.54  ? 439 ILE C CB  1 
ATOM   10897 C CG1 . ILE C 1 439 ? 125.753 130.428 164.306 1.00 47.54  ? 439 ILE C CG1 1 
ATOM   10898 C CG2 . ILE C 1 439 ? 126.991 130.208 166.473 1.00 47.54  ? 439 ILE C CG2 1 
ATOM   10899 C CD1 . ILE C 1 439 ? 124.362 130.402 164.877 1.00 47.54  ? 439 ILE C CD1 1 
ATOM   10900 N N   . ASP C 1 440 ? 128.444 133.555 166.260 1.00 50.44  ? 440 ASP C N   1 
ATOM   10901 C CA  . ASP C 1 440 ? 129.391 134.132 167.208 1.00 50.44  ? 440 ASP C CA  1 
ATOM   10902 C C   . ASP C 1 440 ? 128.800 135.344 167.920 1.00 50.44  ? 440 ASP C C   1 
ATOM   10903 O O   . ASP C 1 440 ? 128.961 135.494 169.138 1.00 50.44  ? 440 ASP C O   1 
ATOM   10904 C CB  . ASP C 1 440 ? 130.689 134.505 166.495 1.00 50.44  ? 440 ASP C CB  1 
ATOM   10905 C CG  . ASP C 1 440 ? 131.531 133.294 166.147 1.00 50.44  ? 440 ASP C CG  1 
ATOM   10906 O OD1 . ASP C 1 440 ? 131.187 132.179 166.593 1.00 50.44  ? 440 ASP C OD1 1 
ATOM   10907 O OD2 . ASP C 1 440 ? 132.538 133.455 165.425 1.00 50.44  ? 440 ASP C OD2 1 
ATOM   10908 N N   . LEU C 1 441 ? 128.109 136.219 167.182 1.00 52.94  ? 441 LEU C N   1 
ATOM   10909 C CA  . LEU C 1 441 ? 127.569 137.424 167.807 1.00 52.94  ? 441 LEU C CA  1 
ATOM   10910 C C   . LEU C 1 441 ? 126.475 137.091 168.816 1.00 52.94  ? 441 LEU C C   1 
ATOM   10911 O O   . LEU C 1 441 ? 126.416 137.702 169.891 1.00 52.94  ? 441 LEU C O   1 
ATOM   10912 C CB  . LEU C 1 441 ? 127.066 138.406 166.742 1.00 52.94  ? 441 LEU C CB  1 
ATOM   10913 C CG  . LEU C 1 441 ? 125.685 138.323 166.082 1.00 52.94  ? 441 LEU C CG  1 
ATOM   10914 C CD1 . LEU C 1 441 ? 124.618 139.058 166.882 1.00 52.94  ? 441 LEU C CD1 1 
ATOM   10915 C CD2 . LEU C 1 441 ? 125.756 138.882 164.672 1.00 52.94  ? 441 LEU C CD2 1 
ATOM   10916 N N   . THR C 1 442 ? 125.600 136.129 168.502 1.00 54.92  ? 442 THR C N   1 
ATOM   10917 C CA  . THR C 1 442 ? 124.561 135.779 169.474 1.00 54.92  ? 442 THR C CA  1 
ATOM   10918 C C   . THR C 1 442 ? 125.168 135.201 170.754 1.00 54.92  ? 442 THR C C   1 
ATOM   10919 O O   . THR C 1 442 ? 124.763 135.568 171.874 1.00 54.92  ? 442 THR C O   1 
ATOM   10920 C CB  . THR C 1 442 ? 123.556 134.804 168.861 1.00 54.92  ? 442 THR C CB  1 
ATOM   10921 O OG1 . THR C 1 442 ? 124.248 133.784 168.133 1.00 54.92  ? 442 THR C OG1 1 
ATOM   10922 C CG2 . THR C 1 442 ? 122.605 135.536 167.928 1.00 54.92  ? 442 THR C CG2 1 
ATOM   10923 N N   . ASP C 1 443 ? 126.158 134.311 170.611 1.00 57.90  ? 443 ASP C N   1 
ATOM   10924 C CA  . ASP C 1 443 ? 126.806 133.757 171.798 1.00 57.90  ? 443 ASP C CA  1 
ATOM   10925 C C   . ASP C 1 443 ? 127.481 134.850 172.623 1.00 57.90  ? 443 ASP C C   1 
ATOM   10926 O O   . ASP C 1 443 ? 127.382 134.863 173.862 1.00 57.90  ? 443 ASP C O   1 
ATOM   10927 C CB  . ASP C 1 443 ? 127.818 132.686 171.394 1.00 57.90  ? 443 ASP C CB  1 
ATOM   10928 C CG  . ASP C 1 443 ? 127.158 131.393 170.960 1.00 57.90  ? 443 ASP C CG  1 
ATOM   10929 O OD1 . ASP C 1 443 ? 126.019 131.129 171.397 1.00 57.90  ? 443 ASP C OD1 1 
ATOM   10930 O OD2 . ASP C 1 443 ? 127.781 130.635 170.189 1.00 57.90  ? 443 ASP C OD2 1 
ATOM   10931 N N   . SER C 1 444 ? 128.163 135.784 171.953 1.00 59.98  ? 444 SER C N   1 
ATOM   10932 C CA  . SER C 1 444 ? 128.840 136.860 172.669 1.00 59.98  ? 444 SER C CA  1 
ATOM   10933 C C   . SER C 1 444 ? 127.845 137.746 173.406 1.00 59.98  ? 444 SER C C   1 
ATOM   10934 O O   . SER C 1 444 ? 128.125 138.209 174.516 1.00 59.98  ? 444 SER C O   1 
ATOM   10935 C CB  . SER C 1 444 ? 129.685 137.689 171.702 1.00 59.98  ? 444 SER C CB  1 
ATOM   10936 O OG  . SER C 1 444 ? 128.887 138.611 170.984 1.00 59.98  ? 444 SER C OG  1 
ATOM   10937 N N   . GLU C 1 445 ? 126.680 138.002 172.803 1.00 64.02  ? 445 GLU C N   1 
ATOM   10938 C CA  . GLU C 1 445 ? 125.658 138.800 173.477 1.00 64.02  ? 445 GLU C CA  1 
ATOM   10939 C C   . GLU C 1 445 ? 125.200 138.131 174.769 1.00 64.02  ? 445 GLU C C   1 
ATOM   10940 O O   . GLU C 1 445 ? 125.090 138.783 175.821 1.00 64.02  ? 445 GLU C O   1 
ATOM   10941 C CB  . GLU C 1 445 ? 124.471 139.023 172.540 1.00 64.02  ? 445 GLU C CB  1 
ATOM   10942 C CG  . GLU C 1 445 ? 123.607 140.225 172.883 1.00 64.02  ? 445 GLU C CG  1 
ATOM   10943 C CD  . GLU C 1 445 ? 124.322 141.543 172.667 1.00 64.02  ? 445 GLU C CD  1 
ATOM   10944 O OE1 . GLU C 1 445 ? 124.986 141.694 171.621 1.00 64.02  ? 445 GLU C OE1 1 
ATOM   10945 O OE2 . GLU C 1 445 ? 124.217 142.430 173.539 1.00 64.02  ? 445 GLU C OE2 1 
ATOM   10946 N N   . MET C 1 446 ? 124.925 136.823 174.710 1.00 66.04  ? 446 MET C N   1 
ATOM   10947 C CA  . MET C 1 446 ? 124.503 136.127 175.927 1.00 66.04  ? 446 MET C CA  1 
ATOM   10948 C C   . MET C 1 446 ? 125.580 136.201 177.008 1.00 66.04  ? 446 MET C C   1 
ATOM   10949 O O   . MET C 1 446 ? 125.287 136.488 178.182 1.00 66.04  ? 446 MET C O   1 
ATOM   10950 C CB  . MET C 1 446 ? 124.154 134.672 175.615 1.00 66.04  ? 446 MET C CB  1 
ATOM   10951 C CG  . MET C 1 446 ? 123.743 133.850 176.830 1.00 66.04  ? 446 MET C CG  1 
ATOM   10952 S SD  . MET C 1 446 ? 122.002 134.022 177.279 1.00 66.04  ? 446 MET C SD  1 
ATOM   10953 C CE  . MET C 1 446 ? 122.100 135.144 178.670 1.00 66.04  ? 446 MET C CE  1 
ATOM   10954 N N   . ASN C 1 447 ? 126.838 135.963 176.624 1.00 66.90  ? 447 ASN C N   1 
ATOM   10955 C CA  . ASN C 1 447 ? 127.922 136.000 177.602 1.00 66.90  ? 447 ASN C CA  1 
ATOM   10956 C C   . ASN C 1 447 ? 128.092 137.393 178.198 1.00 66.90  ? 447 ASN C C   1 
ATOM   10957 O O   . ASN C 1 447 ? 128.368 137.535 179.395 1.00 66.90  ? 447 ASN C O   1 
ATOM   10958 C CB  . ASN C 1 447 ? 129.224 135.527 176.960 1.00 66.90  ? 447 ASN C CB  1 
ATOM   10959 C CG  . ASN C 1 447 ? 129.280 134.024 176.812 1.00 66.90  ? 447 ASN C CG  1 
ATOM   10960 O OD1 . ASN C 1 447 ? 129.375 133.501 175.704 1.00 66.90  ? 447 ASN C OD1 1 
ATOM   10961 N ND2 . ASN C 1 447 ? 129.212 133.318 177.934 1.00 66.90  ? 447 ASN C ND2 1 
ATOM   10962 N N   . LYS C 1 448 ? 127.943 138.434 177.376 1.00 68.80  ? 448 LYS C N   1 
ATOM   10963 C CA  . LYS C 1 448 ? 128.062 139.798 177.875 1.00 68.80  ? 448 LYS C CA  1 
ATOM   10964 C C   . LYS C 1 448 ? 126.981 140.106 178.901 1.00 68.80  ? 448 LYS C C   1 
ATOM   10965 O O   . LYS C 1 448 ? 127.253 140.742 179.927 1.00 68.80  ? 448 LYS C O   1 
ATOM   10966 C CB  . LYS C 1 448 ? 127.990 140.789 176.715 1.00 68.80  ? 448 LYS C CB  1 
ATOM   10967 C CG  . LYS C 1 448 ? 129.342 141.275 176.227 1.00 68.80  ? 448 LYS C CG  1 
ATOM   10968 C CD  . LYS C 1 448 ? 129.234 141.951 174.868 1.00 68.80  ? 448 LYS C CD  1 
ATOM   10969 C CE  . LYS C 1 448 ? 127.963 142.779 174.752 1.00 68.80  ? 448 LYS C CE  1 
ATOM   10970 N NZ  . LYS C 1 448 ? 127.437 142.800 173.358 1.00 68.80  ? 448 LYS C NZ  1 
ATOM   10971 N N   . LEU C 1 449 ? 125.744 139.674 178.637 1.00 71.69  ? 449 LEU C N   1 
ATOM   10972 C CA  . LEU C 1 449 ? 124.684 139.892 179.618 1.00 71.69  ? 449 LEU C CA  1 
ATOM   10973 C C   . LEU C 1 449 ? 125.004 139.194 180.936 1.00 71.69  ? 449 LEU C C   1 
ATOM   10974 O O   . LEU C 1 449 ? 124.848 139.782 182.019 1.00 71.69  ? 449 LEU C O   1 
ATOM   10975 C CB  . LEU C 1 449 ? 123.341 139.413 179.070 1.00 71.69  ? 449 LEU C CB  1 
ATOM   10976 C CG  . LEU C 1 449 ? 122.138 139.661 179.982 1.00 71.69  ? 449 LEU C CG  1 
ATOM   10977 C CD1 . LEU C 1 449 ? 122.038 141.130 180.362 1.00 71.69  ? 449 LEU C CD1 1 
ATOM   10978 C CD2 . LEU C 1 449 ? 120.853 139.186 179.328 1.00 71.69  ? 449 LEU C CD2 1 
ATOM   10979 N N   . PHE C 1 450 ? 125.475 137.943 180.865 1.00 76.24  ? 450 PHE C N   1 
ATOM   10980 C CA  . PHE C 1 450 ? 125.824 137.236 182.096 1.00 76.24  ? 450 PHE C CA  1 
ATOM   10981 C C   . PHE C 1 450 ? 126.938 137.953 182.854 1.00 76.24  ? 450 PHE C C   1 
ATOM   10982 O O   . PHE C 1 450 ? 126.884 138.076 184.084 1.00 76.24  ? 450 PHE C O   1 
ATOM   10983 C CB  . PHE C 1 450 ? 126.231 135.796 181.790 1.00 76.24  ? 450 PHE C CB  1 
ATOM   10984 C CG  . PHE C 1 450 ? 126.521 134.976 183.016 1.00 76.24  ? 450 PHE C CG  1 
ATOM   10985 C CD1 . PHE C 1 450 ? 125.494 134.374 183.722 1.00 76.24  ? 450 PHE C CD1 1 
ATOM   10986 C CD2 . PHE C 1 450 ? 127.820 134.810 183.465 1.00 76.24  ? 450 PHE C CD2 1 
ATOM   10987 C CE1 . PHE C 1 450 ? 125.756 133.621 184.849 1.00 76.24  ? 450 PHE C CE1 1 
ATOM   10988 C CE2 . PHE C 1 450 ? 128.088 134.059 184.591 1.00 76.24  ? 450 PHE C CE2 1 
ATOM   10989 C CZ  . PHE C 1 450 ? 127.054 133.463 185.284 1.00 76.24  ? 450 PHE C CZ  1 
ATOM   10990 N N   . GLU C 1 451 ? 127.958 138.432 182.136 1.00 77.71  ? 451 GLU C N   1 
ATOM   10991 C CA  . GLU C 1 451 ? 129.077 139.101 182.795 1.00 77.71  ? 451 GLU C CA  1 
ATOM   10992 C C   . GLU C 1 451 ? 128.649 140.415 183.436 1.00 77.71  ? 451 GLU C C   1 
ATOM   10993 O O   . GLU C 1 451 ? 129.124 140.763 184.522 1.00 77.71  ? 451 GLU C O   1 
ATOM   10994 C CB  . GLU C 1 451 ? 130.212 139.336 181.801 1.00 77.71  ? 451 GLU C CB  1 
ATOM   10995 C CG  . GLU C 1 451 ? 131.578 138.959 182.343 1.00 77.71  ? 451 GLU C CG  1 
ATOM   10996 C CD  . GLU C 1 451 ? 131.554 137.660 183.126 1.00 77.71  ? 451 GLU C CD  1 
ATOM   10997 O OE1 . GLU C 1 451 ? 131.339 136.596 182.508 1.00 77.71  ? 451 GLU C OE1 1 
ATOM   10998 O OE2 . GLU C 1 451 ? 131.751 137.702 184.359 1.00 77.71  ? 451 GLU C OE2 1 
ATOM   10999 N N   . LYS C 1 452 ? 127.770 141.169 182.774 1.00 79.26  ? 452 LYS C N   1 
ATOM   11000 C CA  . LYS C 1 452 ? 127.266 142.401 183.374 1.00 79.26  ? 452 LYS C CA  1 
ATOM   11001 C C   . LYS C 1 452 ? 126.488 142.108 184.652 1.00 79.26  ? 452 LYS C C   1 
ATOM   11002 O O   . LYS C 1 452 ? 126.655 142.800 185.669 1.00 79.26  ? 452 LYS C O   1 
ATOM   11003 C CB  . LYS C 1 452 ? 126.394 143.151 182.370 1.00 79.26  ? 452 LYS C CB  1 
ATOM   11004 C CG  . LYS C 1 452 ? 125.877 144.488 182.865 1.00 79.26  ? 452 LYS C CG  1 
ATOM   11005 C CD  . LYS C 1 452 ? 124.837 145.056 181.916 1.00 79.26  ? 452 LYS C CD  1 
ATOM   11006 C CE  . LYS C 1 452 ? 124.090 146.218 182.547 1.00 79.26  ? 452 LYS C CE  1 
ATOM   11007 N NZ  . LYS C 1 452 ? 122.929 145.762 183.359 1.00 79.26  ? 452 LYS C NZ  1 
ATOM   11008 N N   . THR C 1 453 ? 125.645 141.071 184.625 1.00 80.70  ? 453 THR C N   1 
ATOM   11009 C CA  . THR C 1 453 ? 124.923 140.693 185.836 1.00 80.70  ? 453 THR C CA  1 
ATOM   11010 C C   . THR C 1 453 ? 125.888 140.301 186.949 1.00 80.70  ? 453 THR C C   1 
ATOM   11011 O O   . THR C 1 453 ? 125.687 140.666 188.113 1.00 80.70  ? 453 THR C O   1 
ATOM   11012 C CB  . THR C 1 453 ? 123.948 139.554 185.539 1.00 80.70  ? 453 THR C CB  1 
ATOM   11013 O OG1 . THR C 1 453 ? 122.945 140.012 184.626 1.00 80.70  ? 453 THR C OG1 1 
ATOM   11014 C CG2 . THR C 1 453 ? 123.273 139.084 186.817 1.00 80.70  ? 453 THR C CG2 1 
ATOM   11015 N N   . ARG C 1 454 ? 126.952 139.567 186.609 1.00 82.72  ? 454 ARG C N   1 
ATOM   11016 C CA  . ARG C 1 454 ? 127.959 139.227 187.613 1.00 82.72  ? 454 ARG C CA  1 
ATOM   11017 C C   . ARG C 1 454 ? 128.629 140.476 188.172 1.00 82.72  ? 454 ARG C C   1 
ATOM   11018 O O   . ARG C 1 454 ? 128.921 140.549 189.371 1.00 82.72  ? 454 ARG C O   1 
ATOM   11019 C CB  . ARG C 1 454 ? 129.010 138.285 187.028 1.00 82.72  ? 454 ARG C CB  1 
ATOM   11020 C CG  . ARG C 1 454 ? 129.860 137.605 188.091 1.00 82.72  ? 454 ARG C CG  1 
ATOM   11021 C CD  . ARG C 1 454 ? 131.034 136.852 187.490 1.00 82.72  ? 454 ARG C CD  1 
ATOM   11022 N NE  . ARG C 1 454 ? 130.904 135.411 187.667 1.00 82.72  ? 454 ARG C NE  1 
ATOM   11023 C CZ  . ARG C 1 454 ? 131.144 134.514 186.721 1.00 82.72  ? 454 ARG C CZ  1 
ATOM   11024 N NH1 . ARG C 1 454 ? 131.542 134.875 185.512 1.00 82.72  ? 454 ARG C NH1 1 
ATOM   11025 N NH2 . ARG C 1 454 ? 130.980 133.224 186.993 1.00 82.72  ? 454 ARG C NH2 1 
ATOM   11026 N N   . ARG C 1 455 ? 128.896 141.464 187.314 1.00 85.12  ? 455 ARG C N   1 
ATOM   11027 C CA  . ARG C 1 455 ? 129.500 142.707 187.784 1.00 85.12  ? 455 ARG C CA  1 
ATOM   11028 C C   . ARG C 1 455 ? 128.600 143.414 188.786 1.00 85.12  ? 455 ARG C C   1 
ATOM   11029 O O   . ARG C 1 455 ? 129.084 143.971 189.778 1.00 85.12  ? 455 ARG C O   1 
ATOM   11030 C CB  . ARG C 1 455 ? 129.807 143.635 186.608 1.00 85.12  ? 455 ARG C CB  1 
ATOM   11031 C CG  . ARG C 1 455 ? 131.038 143.257 185.808 1.00 85.12  ? 455 ARG C CG  1 
ATOM   11032 C CD  . ARG C 1 455 ? 131.482 144.404 184.918 1.00 85.12  ? 455 ARG C CD  1 
ATOM   11033 N NE  . ARG C 1 455 ? 131.590 144.003 183.521 1.00 85.12  ? 455 ARG C NE  1 
ATOM   11034 C CZ  . ARG C 1 455 ? 130.898 144.548 182.530 1.00 85.12  ? 455 ARG C CZ  1 
ATOM   11035 N NH1 . ARG C 1 455 ? 130.050 145.541 182.743 1.00 85.12  ? 455 ARG C NH1 1 
ATOM   11036 N NH2 . ARG C 1 455 ? 131.064 144.087 181.294 1.00 85.12  ? 455 ARG C NH2 1 
ATOM   11037 N N   . GLN C 1 456 ? 127.287 143.421 188.538 1.00 88.43  ? 456 GLN C N   1 
ATOM   11038 C CA  . GLN C 1 456 ? 126.379 144.095 189.465 1.00 88.43  ? 456 GLN C CA  1 
ATOM   11039 C C   . GLN C 1 456 ? 126.420 143.456 190.851 1.00 88.43  ? 456 GLN C C   1 
ATOM   11040 O O   . GLN C 1 456 ? 126.502 144.156 191.867 1.00 88.43  ? 456 GLN C O   1 
ATOM   11041 C CB  . GLN C 1 456 ? 124.955 144.094 188.914 1.00 88.43  ? 456 GLN C CB  1 
ATOM   11042 C CG  . GLN C 1 456 ? 124.717 145.111 187.817 1.00 88.43  ? 456 GLN C CG  1 
ATOM   11043 C CD  . GLN C 1 456 ? 123.245 145.380 187.590 1.00 88.43  ? 456 GLN C CD  1 
ATOM   11044 O OE1 . GLN C 1 456 ? 122.759 145.331 186.462 1.00 88.43  ? 456 GLN C OE1 1 
ATOM   11045 N NE2 . GLN C 1 456 ? 122.526 145.671 188.666 1.00 88.43  ? 456 GLN C NE2 1 
ATOM   11046 N N   . LEU C 1 457 ? 126.367 142.127 190.914 1.00 90.44  ? 457 LEU C N   1 
ATOM   11047 C CA  . LEU C 1 457 ? 126.436 141.403 192.185 1.00 90.44  ? 457 LEU C CA  1 
ATOM   11048 C C   . LEU C 1 457 ? 127.903 141.206 192.544 1.00 90.44  ? 457 LEU C C   1 
ATOM   11049 O O   . LEU C 1 457 ? 128.540 140.231 192.142 1.00 90.44  ? 457 LEU C O   1 
ATOM   11050 C CB  . LEU C 1 457 ? 125.707 140.070 192.091 1.00 90.44  ? 457 LEU C CB  1 
ATOM   11051 C CG  . LEU C 1 457 ? 124.239 140.085 191.665 1.00 90.44  ? 457 LEU C CG  1 
ATOM   11052 C CD1 . LEU C 1 457 ? 123.873 138.766 191.010 1.00 90.44  ? 457 LEU C CD1 1 
ATOM   11053 C CD2 . LEU C 1 457 ? 123.336 140.361 192.853 1.00 90.44  ? 457 LEU C CD2 1 
ATOM   11054 N N   . ARG C 1 458 ? 128.447 142.139 193.326 1.00 94.69  ? 458 ARG C N   1 
ATOM   11055 C CA  . ARG C 1 458 ? 129.885 142.147 193.575 1.00 94.69  ? 458 ARG C CA  1 
ATOM   11056 C C   . ARG C 1 458 ? 130.296 141.023 194.521 1.00 94.69  ? 458 ARG C C   1 
ATOM   11057 O O   . ARG C 1 458 ? 131.055 140.125 194.142 1.00 94.69  ? 458 ARG C O   1 
ATOM   11058 C CB  . ARG C 1 458 ? 130.306 143.510 194.122 1.00 94.69  ? 458 ARG C CB  1 
ATOM   11059 C CG  . ARG C 1 458 ? 130.408 144.578 193.048 1.00 94.69  ? 458 ARG C CG  1 
ATOM   11060 C CD  . ARG C 1 458 ? 130.632 145.955 193.640 1.00 94.69  ? 458 ARG C CD  1 
ATOM   11061 N NE  . ARG C 1 458 ? 131.786 145.997 194.530 1.00 94.69  ? 458 ARG C NE  1 
ATOM   11062 C CZ  . ARG C 1 458 ? 132.430 147.107 194.862 1.00 94.69  ? 458 ARG C CZ  1 
ATOM   11063 N NH1 . ARG C 1 458 ? 132.065 148.286 194.385 1.00 94.69  ? 458 ARG C NH1 1 
ATOM   11064 N NH2 . ARG C 1 458 ? 133.464 147.033 195.693 1.00 94.69  ? 458 ARG C NH2 1 
ATOM   11065 N N   . GLU C 1 459 ? 129.797 141.049 195.758 1.00 97.57  ? 459 GLU C N   1 
ATOM   11066 C CA  . GLU C 1 459 ? 130.167 140.044 196.746 1.00 97.57  ? 459 GLU C CA  1 
ATOM   11067 C C   . GLU C 1 459 ? 128.985 139.373 197.431 1.00 97.57  ? 459 GLU C C   1 
ATOM   11068 O O   . GLU C 1 459 ? 129.202 138.479 198.255 1.00 97.57  ? 459 GLU C O   1 
ATOM   11069 C CB  . GLU C 1 459 ? 131.080 140.656 197.820 1.00 97.57  ? 459 GLU C CB  1 
ATOM   11070 C CG  . GLU C 1 459 ? 132.436 141.116 197.307 1.00 97.57  ? 459 GLU C CG  1 
ATOM   11071 C CD  . GLU C 1 459 ? 133.325 139.963 196.875 1.00 97.57  ? 459 GLU C CD  1 
ATOM   11072 O OE1 . GLU C 1 459 ? 134.281 140.204 196.109 1.00 97.57  ? 459 GLU C OE1 1 
ATOM   11073 O OE2 . GLU C 1 459 ? 133.076 138.819 197.310 1.00 97.57  ? 459 GLU C OE2 1 
ATOM   11074 N N   . ASN C 1 460 ? 127.751 139.765 197.123 1.00 98.28  ? 460 ASN C N   1 
ATOM   11075 C CA  . ASN C 1 460 ? 126.582 139.196 197.779 1.00 98.28  ? 460 ASN C CA  1 
ATOM   11076 C C   . ASN C 1 460 ? 126.034 137.962 197.074 1.00 98.28  ? 460 ASN C C   1 
ATOM   11077 O O   . ASN C 1 460 ? 125.077 137.360 197.571 1.00 98.28  ? 460 ASN C O   1 
ATOM   11078 C CB  . ASN C 1 460 ? 125.475 140.248 197.894 1.00 98.28  ? 460 ASN C CB  1 
ATOM   11079 C CG  . ASN C 1 460 ? 126.019 141.652 198.045 1.00 98.28  ? 460 ASN C CG  1 
ATOM   11080 O OD1 . ASN C 1 460 ? 125.800 142.508 197.192 1.00 98.28  ? 460 ASN C OD1 1 
ATOM   11081 N ND2 . ASN C 1 460 ? 126.729 141.897 199.139 1.00 98.28  ? 460 ASN C ND2 1 
ATOM   11082 N N   . ALA C 1 461 ? 126.611 137.568 195.942 1.00 96.45  ? 461 ALA C N   1 
ATOM   11083 C CA  . ALA C 1 461 ? 126.092 136.455 195.162 1.00 96.45  ? 461 ALA C CA  1 
ATOM   11084 C C   . ALA C 1 461 ? 127.244 135.586 194.682 1.00 96.45  ? 461 ALA C C   1 
ATOM   11085 O O   . ALA C 1 461 ? 128.399 136.018 194.635 1.00 96.45  ? 461 ALA C O   1 
ATOM   11086 C CB  . ALA C 1 461 ? 125.263 136.939 193.966 1.00 96.45  ? 461 ALA C CB  1 
ATOM   11087 N N   . GLU C 1 462 ? 126.915 134.345 194.332 1.00 94.95  ? 462 GLU C N   1 
ATOM   11088 C CA  . GLU C 1 462 ? 127.902 133.401 193.828 1.00 94.95  ? 462 GLU C CA  1 
ATOM   11089 C C   . GLU C 1 462 ? 127.367 132.651 192.615 1.00 94.95  ? 462 GLU C C   1 
ATOM   11090 O O   . GLU C 1 462 ? 126.169 132.377 192.504 1.00 94.95  ? 462 GLU C O   1 
ATOM   11091 C CB  . GLU C 1 462 ? 128.329 132.404 194.908 1.00 94.95  ? 462 GLU C CB  1 
ATOM   11092 C CG  . GLU C 1 462 ? 129.641 131.703 194.599 1.00 94.95  ? 462 GLU C CG  1 
ATOM   11093 C CD  . GLU C 1 462 ? 130.333 131.182 195.840 1.00 94.95  ? 462 GLU C CD  1 
ATOM   11094 O OE1 . GLU C 1 462 ? 130.196 131.810 196.911 1.00 94.95  ? 462 GLU C OE1 1 
ATOM   11095 O OE2 . GLU C 1 462 ? 130.992 130.126 195.746 1.00 94.95  ? 462 GLU C OE2 1 
ATOM   11096 N N   . ASP C 1 463 ? 128.283 132.314 191.709 1.00 89.89  ? 463 ASP C N   1 
ATOM   11097 C CA  . ASP C 1 463 ? 127.961 131.579 190.492 1.00 89.89  ? 463 ASP C CA  1 
ATOM   11098 C C   . ASP C 1 463 ? 127.853 130.090 190.802 1.00 89.89  ? 463 ASP C C   1 
ATOM   11099 O O   . ASP C 1 463 ? 128.777 129.503 191.375 1.00 89.89  ? 463 ASP C O   1 
ATOM   11100 C CB  . ASP C 1 463 ? 129.037 131.841 189.439 1.00 89.89  ? 463 ASP C CB  1 
ATOM   11101 C CG  . ASP C 1 463 ? 128.757 131.147 188.117 1.00 89.89  ? 463 ASP C CG  1 
ATOM   11102 O OD1 . ASP C 1 463 ? 127.665 130.566 187.952 1.00 89.89  ? 463 ASP C OD1 1 
ATOM   11103 O OD2 . ASP C 1 463 ? 129.641 131.188 187.235 1.00 89.89  ? 463 ASP C OD2 1 
ATOM   11104 N N   . MET C 1 464 ? 126.728 129.476 190.429 1.00 89.21  ? 464 MET C N   1 
ATOM   11105 C CA  . MET C 1 464 ? 126.568 128.039 190.621 1.00 89.21  ? 464 MET C CA  1 
ATOM   11106 C C   . MET C 1 464 ? 127.271 127.208 189.557 1.00 89.21  ? 464 MET C C   1 
ATOM   11107 O O   . MET C 1 464 ? 127.396 125.992 189.734 1.00 89.21  ? 464 MET C O   1 
ATOM   11108 C CB  . MET C 1 464 ? 125.088 127.645 190.657 1.00 89.21  ? 464 MET C CB  1 
ATOM   11109 C CG  . MET C 1 464 ? 124.445 127.791 192.021 1.00 89.21  ? 464 MET C CG  1 
ATOM   11110 S SD  . MET C 1 464 ? 123.288 129.162 192.108 1.00 89.21  ? 464 MET C SD  1 
ATOM   11111 C CE  . MET C 1 464 ? 121.870 128.452 191.283 1.00 89.21  ? 464 MET C CE  1 
ATOM   11112 N N   . GLY C 1 465 ? 127.724 127.818 188.465 1.00 87.62  ? 465 GLY C N   1 
ATOM   11113 C CA  . GLY C 1 465 ? 128.395 127.086 187.412 1.00 87.62  ? 465 GLY C CA  1 
ATOM   11114 C C   . GLY C 1 465 ? 127.499 126.577 186.305 1.00 87.62  ? 465 GLY C C   1 
ATOM   11115 O O   . GLY C 1 465 ? 128.003 125.963 185.356 1.00 87.62  ? 465 GLY C O   1 
ATOM   11116 N N   . ASN C 1 466 ? 126.190 126.803 186.398 1.00 84.90  ? 466 ASN C N   1 
ATOM   11117 C CA  . ASN C 1 466 ? 125.244 126.465 185.343 1.00 84.90  ? 466 ASN C CA  1 
ATOM   11118 C C   . ASN C 1 466 ? 124.542 127.706 184.799 1.00 84.90  ? 466 ASN C C   1 
ATOM   11119 O O   . ASN C 1 466 ? 123.383 127.641 184.385 1.00 84.90  ? 466 ASN C O   1 
ATOM   11120 C CB  . ASN C 1 466 ? 124.224 125.445 185.848 1.00 84.90  ? 466 ASN C CB  1 
ATOM   11121 C CG  . ASN C 1 466 ? 123.428 125.955 187.032 1.00 84.90  ? 466 ASN C CG  1 
ATOM   11122 O OD1 . ASN C 1 466 ? 123.684 127.044 187.541 1.00 84.90  ? 466 ASN C OD1 1 
ATOM   11123 N ND2 . ASN C 1 466 ? 122.461 125.165 187.481 1.00 84.90  ? 466 ASN C ND2 1 
ATOM   11124 N N   . GLY C 1 467 ? 125.234 128.844 184.807 1.00 82.93  ? 467 GLY C N   1 
ATOM   11125 C CA  . GLY C 1 467 ? 124.654 130.085 184.338 1.00 82.93  ? 467 GLY C CA  1 
ATOM   11126 C C   . GLY C 1 467 ? 123.701 130.741 185.305 1.00 82.93  ? 467 GLY C C   1 
ATOM   11127 O O   . GLY C 1 467 ? 122.889 131.572 184.890 1.00 82.93  ? 467 GLY C O   1 
ATOM   11128 N N   . CYS C 1 468 ? 123.782 130.403 186.590 1.00 85.75  ? 468 CYS C N   1 
ATOM   11129 C CA  . CYS C 1 468 ? 122.783 130.793 187.569 1.00 85.75  ? 468 CYS C CA  1 
ATOM   11130 C C   . CYS C 1 468 ? 123.497 131.346 188.796 1.00 85.75  ? 468 CYS C C   1 
ATOM   11131 O O   . CYS C 1 468 ? 124.491 130.777 189.255 1.00 85.75  ? 468 CYS C O   1 
ATOM   11132 C CB  . CYS C 1 468 ? 121.940 129.576 187.963 1.00 85.75  ? 468 CYS C CB  1 
ATOM   11133 S SG  . CYS C 1 468 ? 120.513 129.214 186.912 1.00 85.75  ? 468 CYS C SG  1 
ATOM   11134 N N   . PHE C 1 469 ? 122.992 132.456 189.333 1.00 86.57  ? 469 PHE C N   1 
ATOM   11135 C CA  . PHE C 1 469 ? 123.538 133.079 190.530 1.00 86.57  ? 469 PHE C CA  1 
ATOM   11136 C C   . PHE C 1 469 ? 122.666 132.751 191.733 1.00 86.57  ? 469 PHE C C   1 
ATOM   11137 O O   . PHE C 1 469 ? 121.439 132.672 191.620 1.00 86.57  ? 469 PHE C O   1 
ATOM   11138 C CB  . PHE C 1 469 ? 123.621 134.600 190.379 1.00 86.57  ? 469 PHE C CB  1 
ATOM   11139 C CG  . PHE C 1 469 ? 124.660 135.064 189.408 1.00 86.57  ? 469 PHE C CG  1 
ATOM   11140 C CD1 . PHE C 1 469 ? 126.006 134.973 189.713 1.00 86.57  ? 469 PHE C CD1 1 
ATOM   11141 C CD2 . PHE C 1 469 ? 124.289 135.592 188.185 1.00 86.57  ? 469 PHE C CD2 1 
ATOM   11142 C CE1 . PHE C 1 469 ? 126.960 135.404 188.818 1.00 86.57  ? 469 PHE C CE1 1 
ATOM   11143 C CE2 . PHE C 1 469 ? 125.236 136.022 187.287 1.00 86.57  ? 469 PHE C CE2 1 
ATOM   11144 C CZ  . PHE C 1 469 ? 126.573 135.928 187.603 1.00 86.57  ? 469 PHE C CZ  1 
ATOM   11145 N N   . LYS C 1 470 ? 123.307 132.572 192.883 1.00 93.75  ? 470 LYS C N   1 
ATOM   11146 C CA  . LYS C 1 470 ? 122.616 132.436 194.159 1.00 93.75  ? 470 LYS C CA  1 
ATOM   11147 C C   . LYS C 1 470 ? 122.986 133.626 195.028 1.00 93.75  ? 470 LYS C C   1 
ATOM   11148 O O   . LYS C 1 470 ? 124.173 133.893 195.249 1.00 93.75  ? 470 LYS C O   1 
ATOM   11149 C CB  . LYS C 1 470 ? 122.971 131.117 194.847 1.00 93.75  ? 470 LYS C CB  1 
ATOM   11150 C CG  . LYS C 1 470 ? 122.486 130.997 196.277 1.00 93.75  ? 470 LYS C CG  1 
ATOM   11151 C CD  . LYS C 1 470 ? 123.353 130.018 197.050 1.00 93.75  ? 470 LYS C CD  1 
ATOM   11152 C CE  . LYS C 1 470 ? 124.374 130.730 197.912 1.00 93.75  ? 470 LYS C CE  1 
ATOM   11153 N NZ  . LYS C 1 470 ? 124.946 129.836 198.958 1.00 93.75  ? 470 LYS C NZ  1 
ATOM   11154 N N   . ILE C 1 471 ? 121.970 134.341 195.502 1.00 96.24  ? 471 ILE C N   1 
ATOM   11155 C CA  . ILE C 1 471 ? 122.134 135.549 196.299 1.00 96.24  ? 471 ILE C CA  1 
ATOM   11156 C C   . ILE C 1 471 ? 121.941 135.185 197.763 1.00 96.24  ? 471 ILE C C   1 
ATOM   11157 O O   . ILE C 1 471 ? 120.920 134.589 198.136 1.00 96.24  ? 471 ILE C O   1 
ATOM   11158 C CB  . ILE C 1 471 ? 121.140 136.638 195.861 1.00 96.24  ? 471 ILE C CB  1 
ATOM   11159 C CG1 . ILE C 1 471 ? 121.041 136.677 194.334 1.00 96.24  ? 471 ILE C CG1 1 
ATOM   11160 C CG2 . ILE C 1 471 ? 121.556 137.994 196.406 1.00 96.24  ? 471 ILE C CG2 1 
ATOM   11161 C CD1 . ILE C 1 471 ? 120.231 137.832 193.800 1.00 96.24  ? 471 ILE C CD1 1 
ATOM   11162 N N   . TYR C 1 472 ? 122.918 135.550 198.593 1.00 99.21  ? 472 TYR C N   1 
ATOM   11163 C CA  . TYR C 1 472 ? 122.975 135.113 199.982 1.00 99.21  ? 472 TYR C CA  1 
ATOM   11164 C C   . TYR C 1 472 ? 122.048 135.894 200.904 1.00 99.21  ? 472 TYR C C   1 
ATOM   11165 O O   . TYR C 1 472 ? 121.831 135.462 202.040 1.00 99.21  ? 472 TYR C O   1 
ATOM   11166 C CB  . TYR C 1 472 ? 124.411 135.221 200.502 1.00 99.21  ? 472 TYR C CB  1 
ATOM   11167 C CG  . TYR C 1 472 ? 125.374 134.234 199.879 1.00 99.21  ? 472 TYR C CG  1 
ATOM   11168 C CD1 . TYR C 1 472 ? 125.865 134.427 198.594 1.00 99.21  ? 472 TYR C CD1 1 
ATOM   11169 C CD2 . TYR C 1 472 ? 125.802 133.117 200.582 1.00 99.21  ? 472 TYR C CD2 1 
ATOM   11170 C CE1 . TYR C 1 472 ? 126.747 133.531 198.024 1.00 99.21  ? 472 TYR C CE1 1 
ATOM   11171 C CE2 . TYR C 1 472 ? 126.688 132.218 200.022 1.00 99.21  ? 472 TYR C CE2 1 
ATOM   11172 C CZ  . TYR C 1 472 ? 127.156 132.429 198.741 1.00 99.21  ? 472 TYR C CZ  1 
ATOM   11173 O OH  . TYR C 1 472 ? 128.035 131.533 198.177 1.00 99.21  ? 472 TYR C OH  1 
ATOM   11174 N N   . HIS C 1 473 ? 121.502 137.019 200.457 1.00 99.26  ? 473 HIS C N   1 
ATOM   11175 C CA  . HIS C 1 473 ? 120.605 137.826 201.268 1.00 99.26  ? 473 HIS C CA  1 
ATOM   11176 C C   . HIS C 1 473 ? 119.177 137.694 200.755 1.00 99.26  ? 473 HIS C C   1 
ATOM   11177 O O   . HIS C 1 473 ? 118.907 137.027 199.753 1.00 99.26  ? 473 HIS C O   1 
ATOM   11178 C CB  . HIS C 1 473 ? 121.051 139.295 201.277 1.00 99.26  ? 473 HIS C CB  1 
ATOM   11179 C CG  . HIS C 1 473 ? 120.791 140.021 199.993 1.00 99.26  ? 473 HIS C CG  1 
ATOM   11180 N ND1 . HIS C 1 473 ? 119.545 140.495 199.643 1.00 99.26  ? 473 HIS C ND1 1 
ATOM   11181 C CD2 . HIS C 1 473 ? 121.620 140.360 198.978 1.00 99.26  ? 473 HIS C CD2 1 
ATOM   11182 C CE1 . HIS C 1 473 ? 119.617 141.093 198.467 1.00 99.26  ? 473 HIS C CE1 1 
ATOM   11183 N NE2 . HIS C 1 473 ? 120.866 141.025 198.043 1.00 99.26  ? 473 HIS C NE2 1 
ATOM   11184 N N   . LYS C 1 474 ? 118.255 138.340 201.463 1.00 99.26  ? 474 LYS C N   1 
ATOM   11185 C CA  . LYS C 1 474 ? 116.839 138.286 201.110 1.00 99.26  ? 474 LYS C CA  1 
ATOM   11186 C C   . LYS C 1 474 ? 116.584 139.288 199.992 1.00 99.26  ? 474 LYS C C   1 
ATOM   11187 O O   . LYS C 1 474 ? 116.625 140.502 200.203 1.00 99.26  ? 474 LYS C O   1 
ATOM   11188 C CB  . LYS C 1 474 ? 115.967 138.568 202.328 1.00 99.26  ? 474 LYS C CB  1 
ATOM   11189 C CG  . LYS C 1 474 ? 114.598 137.916 202.264 1.00 99.26  ? 474 LYS C CG  1 
ATOM   11190 C CD  . LYS C 1 474 ? 114.172 137.393 203.625 1.00 99.26  ? 474 LYS C CD  1 
ATOM   11191 C CE  . LYS C 1 474 ? 114.740 136.007 203.889 1.00 99.26  ? 474 LYS C CE  1 
ATOM   11192 N NZ  . LYS C 1 474 ? 113.916 134.933 203.269 1.00 99.26  ? 474 LYS C NZ  1 
ATOM   11193 N N   . CYS C 1 475 ? 116.319 138.773 198.797 1.00 98.80  ? 475 CYS C N   1 
ATOM   11194 C CA  . CYS C 1 475 ? 116.123 139.578 197.594 1.00 98.80  ? 475 CYS C CA  1 
ATOM   11195 C C   . CYS C 1 475 ? 114.692 139.346 197.116 1.00 98.80  ? 475 CYS C C   1 
ATOM   11196 O O   . CYS C 1 475 ? 114.411 138.365 196.422 1.00 98.80  ? 475 CYS C O   1 
ATOM   11197 C CB  . CYS C 1 475 ? 117.155 139.201 196.533 1.00 98.80  ? 475 CYS C CB  1 
ATOM   11198 S SG  . CYS C 1 475 ? 117.321 140.304 195.099 1.00 98.80  ? 475 CYS C SG  1 
ATOM   11199 N N   . ASP C 1 476 ? 113.789 140.248 197.493 1.00 98.07  ? 476 ASP C N   1 
ATOM   11200 C CA  . ASP C 1 476 ? 112.382 140.130 197.133 1.00 98.07  ? 476 ASP C CA  1 
ATOM   11201 C C   . ASP C 1 476 ? 112.180 140.618 195.698 1.00 98.07  ? 476 ASP C C   1 
ATOM   11202 O O   . ASP C 1 476 ? 113.138 140.887 194.971 1.00 98.07  ? 476 ASP C O   1 
ATOM   11203 C CB  . ASP C 1 476 ? 111.513 140.890 198.129 1.00 98.07  ? 476 ASP C CB  1 
ATOM   11204 C CG  . ASP C 1 476 ? 111.643 142.389 197.987 1.00 98.07  ? 476 ASP C CG  1 
ATOM   11205 O OD1 . ASP C 1 476 ? 112.784 142.894 198.043 1.00 98.07  ? 476 ASP C OD1 1 
ATOM   11206 O OD2 . ASP C 1 476 ? 110.606 143.063 197.815 1.00 98.07  ? 476 ASP C OD2 1 
ATOM   11207 N N   . ASN C 1 477 ? 110.918 140.750 195.278 1.00 97.97  ? 477 ASN C N   1 
ATOM   11208 C CA  . ASN C 1 477 ? 110.627 141.071 193.883 1.00 97.97  ? 477 ASN C CA  1 
ATOM   11209 C C   . ASN C 1 477 ? 111.170 142.442 193.494 1.00 97.97  ? 477 ASN C C   1 
ATOM   11210 O O   . ASN C 1 477 ? 111.711 142.612 192.395 1.00 97.97  ? 477 ASN C O   1 
ATOM   11211 C CB  . ASN C 1 477 ? 109.121 141.000 193.629 1.00 97.97  ? 477 ASN C CB  1 
ATOM   11212 C CG  . ASN C 1 477 ? 108.580 139.588 193.727 1.00 97.97  ? 477 ASN C CG  1 
ATOM   11213 O OD1 . ASN C 1 477 ? 109.334 138.616 193.682 1.00 97.97  ? 477 ASN C OD1 1 
ATOM   11214 N ND2 . ASN C 1 477 ? 107.265 139.467 193.856 1.00 97.97  ? 477 ASN C ND2 1 
ATOM   11215 N N   . ALA C 1 478 ? 111.026 143.435 194.375 1.00 97.13  ? 478 ALA C N   1 
ATOM   11216 C CA  . ALA C 1 478 ? 111.586 144.752 194.089 1.00 97.13  ? 478 ALA C CA  1 
ATOM   11217 C C   . ALA C 1 478 ? 113.104 144.687 193.980 1.00 97.13  ? 478 ALA C C   1 
ATOM   11218 O O   . ALA C 1 478 ? 113.710 145.410 193.182 1.00 97.13  ? 478 ALA C O   1 
ATOM   11219 C CB  . ALA C 1 478 ? 111.161 145.750 195.166 1.00 97.13  ? 478 ALA C CB  1 
ATOM   11220 N N   . CYS C 1 479 ? 113.733 143.817 194.773 1.00 96.41  ? 479 CYS C N   1 
ATOM   11221 C CA  . CYS C 1 479 ? 115.172 143.594 194.667 1.00 96.41  ? 479 CYS C CA  1 
ATOM   11222 C C   . CYS C 1 479 ? 115.556 143.039 193.296 1.00 96.41  ? 479 CYS C C   1 
ATOM   11223 O O   . CYS C 1 479 ? 116.521 143.509 192.677 1.00 96.41  ? 479 CYS C O   1 
ATOM   11224 C CB  . CYS C 1 479 ? 115.610 142.654 195.792 1.00 96.41  ? 479 CYS C CB  1 
ATOM   11225 S SG  . CYS C 1 479 ? 117.344 142.193 195.844 1.00 96.41  ? 479 CYS C SG  1 
ATOM   11226 N N   . ILE C 1 480 ? 114.806 142.052 192.799 1.00 94.25  ? 480 ILE C N   1 
ATOM   11227 C CA  . ILE C 1 480 ? 115.079 141.503 191.471 1.00 94.25  ? 480 ILE C CA  1 
ATOM   11228 C C   . ILE C 1 480 ? 114.875 142.567 190.401 1.00 94.25  ? 480 ILE C C   1 
ATOM   11229 O O   . ILE C 1 480 ? 115.632 142.646 189.428 1.00 94.25  ? 480 ILE C O   1 
ATOM   11230 C CB  . ILE C 1 480 ? 114.208 140.263 191.200 1.00 94.25  ? 480 ILE C CB  1 
ATOM   11231 C CG1 . ILE C 1 480 ? 114.042 139.422 192.465 1.00 94.25  ? 480 ILE C CG1 1 
ATOM   11232 C CG2 . ILE C 1 480 ? 114.797 139.435 190.069 1.00 94.25  ? 480 ILE C CG2 1 
ATOM   11233 C CD1 . ILE C 1 480 ? 115.226 138.536 192.771 1.00 94.25  ? 480 ILE C CD1 1 
ATOM   11234 N N   . GLU C 1 481 ? 113.831 143.383 190.550 1.00 95.79  ? 481 GLU C N   1 
ATOM   11235 C CA  . GLU C 1 481 ? 113.588 144.439 189.573 1.00 95.79  ? 481 GLU C CA  1 
ATOM   11236 C C   . GLU C 1 481 ? 114.719 145.459 189.575 1.00 95.79  ? 481 GLU C C   1 
ATOM   11237 O O   . GLU C 1 481 ? 115.125 145.948 188.514 1.00 95.79  ? 481 GLU C O   1 
ATOM   11238 C CB  . GLU C 1 481 ? 112.247 145.113 189.851 1.00 95.79  ? 481 GLU C CB  1 
ATOM   11239 C CG  . GLU C 1 481 ? 111.791 146.055 188.753 1.00 95.79  ? 481 GLU C CG  1 
ATOM   11240 C CD  . GLU C 1 481 ? 110.947 147.198 189.280 1.00 95.79  ? 481 GLU C CD  1 
ATOM   11241 O OE1 . GLU C 1 481 ? 110.216 146.990 190.271 1.00 95.79  ? 481 GLU C OE1 1 
ATOM   11242 O OE2 . GLU C 1 481 ? 111.012 148.303 188.700 1.00 95.79  ? 481 GLU C OE2 1 
ATOM   11243 N N   . SER C 1 482 ? 115.239 145.793 190.759 1.00 94.80  ? 482 SER C N   1 
ATOM   11244 C CA  . SER C 1 482 ? 116.386 146.690 190.841 1.00 94.80  ? 482 SER C CA  1 
ATOM   11245 C C   . SER C 1 482 ? 117.606 146.083 190.162 1.00 94.80  ? 482 SER C C   1 
ATOM   11246 O O   . SER C 1 482 ? 118.363 146.787 189.484 1.00 94.80  ? 482 SER C O   1 
ATOM   11247 C CB  . SER C 1 482 ? 116.694 147.018 192.301 1.00 94.80  ? 482 SER C CB  1 
ATOM   11248 O OG  . SER C 1 482 ? 117.489 146.005 192.894 1.00 94.80  ? 482 SER C OG  1 
ATOM   11249 N N   . ILE C 1 483 ? 117.818 144.778 190.343 1.00 93.07  ? 483 ILE C N   1 
ATOM   11250 C CA  . ILE C 1 483 ? 118.935 144.111 189.675 1.00 93.07  ? 483 ILE C CA  1 
ATOM   11251 C C   . ILE C 1 483 ? 118.766 144.181 188.161 1.00 93.07  ? 483 ILE C C   1 
ATOM   11252 O O   . ILE C 1 483 ? 119.708 144.495 187.424 1.00 93.07  ? 483 ILE C O   1 
ATOM   11253 C CB  . ILE C 1 483 ? 119.059 142.654 190.157 1.00 93.07  ? 483 ILE C CB  1 
ATOM   11254 C CG1 . ILE C 1 483 ? 119.829 142.587 191.474 1.00 93.07  ? 483 ILE C CG1 1 
ATOM   11255 C CG2 . ILE C 1 483 ? 119.760 141.808 189.107 1.00 93.07  ? 483 ILE C CG2 1 
ATOM   11256 C CD1 . ILE C 1 483 ? 119.755 141.240 192.149 1.00 93.07  ? 483 ILE C CD1 1 
ATOM   11257 N N   . ARG C 1 484 ? 117.555 143.896 187.679 1.00 91.35  ? 484 ARG C N   1 
ATOM   11258 C CA  . ARG C 1 484 ? 117.308 143.864 186.241 1.00 91.35  ? 484 ARG C CA  1 
ATOM   11259 C C   . ARG C 1 484 ? 117.451 145.247 185.618 1.00 91.35  ? 484 ARG C C   1 
ATOM   11260 O O   . ARG C 1 484 ? 117.965 145.380 184.502 1.00 91.35  ? 484 ARG C O   1 
ATOM   11261 C CB  . ARG C 1 484 ? 115.919 143.290 185.965 1.00 91.35  ? 484 ARG C CB  1 
ATOM   11262 C CG  . ARG C 1 484 ? 115.803 141.803 186.248 1.00 91.35  ? 484 ARG C CG  1 
ATOM   11263 C CD  . ARG C 1 484 ? 114.754 141.153 185.368 1.00 91.35  ? 484 ARG C CD  1 
ATOM   11264 N NE  . ARG C 1 484 ? 113.721 140.485 186.150 1.00 91.35  ? 484 ARG C NE  1 
ATOM   11265 C CZ  . ARG C 1 484 ? 112.500 140.964 186.340 1.00 91.35  ? 484 ARG C CZ  1 
ATOM   11266 N NH1 . ARG C 1 484 ? 112.123 142.122 185.825 1.00 91.35  ? 484 ARG C NH1 1 
ATOM   11267 N NH2 . ARG C 1 484 ? 111.633 140.261 187.065 1.00 91.35  ? 484 ARG C NH2 1 
ATOM   11268 N N   . ASN C 1 485 ? 116.999 146.287 186.322 1.00 94.67  ? 485 ASN C N   1 
ATOM   11269 C CA  . ASN C 1 485 ? 117.088 147.641 185.787 1.00 94.67  ? 485 ASN C CA  1 
ATOM   11270 C C   . ASN C 1 485 ? 118.534 148.115 185.706 1.00 94.67  ? 485 ASN C C   1 
ATOM   11271 O O   . ASN C 1 485 ? 118.908 148.830 184.769 1.00 94.67  ? 485 ASN C O   1 
ATOM   11272 C CB  . ASN C 1 485 ? 116.264 148.601 186.644 1.00 94.67  ? 485 ASN C CB  1 
ATOM   11273 C CG  . ASN C 1 485 ? 114.806 148.634 186.243 1.00 94.67  ? 485 ASN C CG  1 
ATOM   11274 O OD1 . ASN C 1 485 ? 114.346 147.802 185.463 1.00 94.67  ? 485 ASN C OD1 1 
ATOM   11275 N ND2 . ASN C 1 485 ? 114.068 149.604 186.773 1.00 94.67  ? 485 ASN C ND2 1 
ATOM   11276 N N   . GLY C 1 486 ? 119.355 147.732 186.671 1.00 94.10  ? 486 GLY C N   1 
ATOM   11277 C CA  . GLY C 1 486 ? 120.699 148.239 186.795 1.00 94.10  ? 486 GLY C CA  1 
ATOM   11278 C C   . GLY C 1 486 ? 120.913 149.216 187.936 1.00 94.10  ? 486 GLY C C   1 
ATOM   11279 O O   . GLY C 1 486 ? 121.966 149.863 187.978 1.00 94.10  ? 486 GLY C O   1 
ATOM   11280 N N   . THR C 1 487 ? 119.953 149.343 188.853 1.00 96.27  ? 487 THR C N   1 
ATOM   11281 C CA  . THR C 1 487 ? 120.046 150.253 189.987 1.00 96.27  ? 487 THR C CA  1 
ATOM   11282 C C   . THR C 1 487 ? 120.305 149.516 191.297 1.00 96.27  ? 487 THR C C   1 
ATOM   11283 O O   . THR C 1 487 ? 119.990 150.037 192.372 1.00 96.27  ? 487 THR C O   1 
ATOM   11284 C CB  . THR C 1 487 ? 118.771 151.092 190.096 1.00 96.27  ? 487 THR C CB  1 
ATOM   11285 O OG1 . THR C 1 487 ? 118.800 151.856 191.308 1.00 96.27  ? 487 THR C OG1 1 
ATOM   11286 C CG2 . THR C 1 487 ? 117.544 150.194 190.099 1.00 96.27  ? 487 THR C CG2 1 
ATOM   11287 N N   . TYR C 1 488 ? 120.870 148.315 191.229 1.00 96.34  ? 488 TYR C N   1 
ATOM   11288 C CA  . TYR C 1 488 ? 121.106 147.524 192.428 1.00 96.34  ? 488 TYR C CA  1 
ATOM   11289 C C   . TYR C 1 488 ? 122.292 148.080 193.206 1.00 96.34  ? 488 TYR C C   1 
ATOM   11290 O O   . TYR C 1 488 ? 123.372 148.295 192.648 1.00 96.34  ? 488 TYR C O   1 
ATOM   11291 C CB  . TYR C 1 488 ? 121.349 146.063 192.049 1.00 96.34  ? 488 TYR C CB  1 
ATOM   11292 C CG  . TYR C 1 488 ? 121.824 145.181 193.183 1.00 96.34  ? 488 TYR C CG  1 
ATOM   11293 C CD1 . TYR C 1 488 ? 120.927 144.646 194.095 1.00 96.34  ? 488 TYR C CD1 1 
ATOM   11294 C CD2 . TYR C 1 488 ? 123.169 144.868 193.327 1.00 96.34  ? 488 TYR C CD2 1 
ATOM   11295 C CE1 . TYR C 1 488 ? 121.357 143.834 195.127 1.00 96.34  ? 488 TYR C CE1 1 
ATOM   11296 C CE2 . TYR C 1 488 ? 123.607 144.059 194.355 1.00 96.34  ? 488 TYR C CE2 1 
ATOM   11297 C CZ  . TYR C 1 488 ? 122.697 143.544 195.251 1.00 96.34  ? 488 TYR C CZ  1 
ATOM   11298 O OH  . TYR C 1 488 ? 123.130 142.736 196.277 1.00 96.34  ? 488 TYR C OH  1 
ATOM   11299 N N   . ASP C 1 489 ? 122.088 148.309 194.500 1.00 100.02 ? 489 ASP C N   1 
ATOM   11300 C CA  . ASP C 1 489 ? 123.114 148.834 195.395 1.00 100.02 ? 489 ASP C CA  1 
ATOM   11301 C C   . ASP C 1 489 ? 123.513 147.721 196.355 1.00 100.02 ? 489 ASP C C   1 
ATOM   11302 O O   . ASP C 1 489 ? 122.702 147.286 197.179 1.00 100.02 ? 489 ASP C O   1 
ATOM   11303 C CB  . ASP C 1 489 ? 122.601 150.059 196.149 1.00 100.02 ? 489 ASP C CB  1 
ATOM   11304 C CG  . ASP C 1 489 ? 123.665 150.696 197.021 1.00 100.02 ? 489 ASP C CG  1 
ATOM   11305 O OD1 . ASP C 1 489 ? 124.864 150.562 196.700 1.00 100.02 ? 489 ASP C OD1 1 
ATOM   11306 O OD2 . ASP C 1 489 ? 123.299 151.334 198.029 1.00 100.02 ? 489 ASP C OD2 1 
ATOM   11307 N N   . HIS C 1 490 ? 124.760 147.260 196.248 1.00 99.91  ? 490 HIS C N   1 
ATOM   11308 C CA  . HIS C 1 490 ? 125.189 146.107 197.031 1.00 99.91  ? 490 HIS C CA  1 
ATOM   11309 C C   . HIS C 1 490 ? 125.451 146.460 198.491 1.00 99.91  ? 490 HIS C C   1 
ATOM   11310 O O   . HIS C 1 490 ? 125.192 145.632 199.374 1.00 99.91  ? 490 HIS C O   1 
ATOM   11311 C CB  . HIS C 1 490 ? 126.437 145.479 196.405 1.00 99.91  ? 490 HIS C CB  1 
ATOM   11312 C CG  . HIS C 1 490 ? 127.631 146.381 196.384 1.00 99.91  ? 490 HIS C CG  1 
ATOM   11313 N ND1 . HIS C 1 490 ? 127.675 147.543 195.644 1.00 99.91  ? 490 HIS C ND1 1 
ATOM   11314 C CD2 . HIS C 1 490 ? 128.831 146.284 197.004 1.00 99.91  ? 490 HIS C CD2 1 
ATOM   11315 C CE1 . HIS C 1 490 ? 128.848 148.126 195.814 1.00 99.91  ? 490 HIS C CE1 1 
ATOM   11316 N NE2 . HIS C 1 490 ? 129.568 147.383 196.635 1.00 99.91  ? 490 HIS C NE2 1 
ATOM   11317 N N   . ASP C 1 491 ? 125.943 147.675 198.759 1.00 100.53 ? 491 ASP C N   1 
ATOM   11318 C CA  . ASP C 1 491 ? 126.266 148.076 200.127 1.00 100.53 ? 491 ASP C CA  1 
ATOM   11319 C C   . ASP C 1 491 ? 125.096 147.842 201.072 1.00 100.53 ? 491 ASP C C   1 
ATOM   11320 O O   . ASP C 1 491 ? 125.281 147.351 202.192 1.00 100.53 ? 491 ASP C O   1 
ATOM   11321 C CB  . ASP C 1 491 ? 126.681 149.548 200.157 1.00 100.53 ? 491 ASP C CB  1 
ATOM   11322 C CG  . ASP C 1 491 ? 128.105 149.762 199.694 1.00 100.53 ? 491 ASP C CG  1 
ATOM   11323 O OD1 . ASP C 1 491 ? 128.913 148.816 199.793 1.00 100.53 ? 491 ASP C OD1 1 
ATOM   11324 O OD2 . ASP C 1 491 ? 128.418 150.880 199.231 1.00 100.53 ? 491 ASP C OD2 1 
ATOM   11325 N N   . ILE C 1 492 ? 123.880 148.152 200.618 1.00 100.00 ? 492 ILE C N   1 
ATOM   11326 C CA  . ILE C 1 492 ? 122.698 148.021 201.464 1.00 100.00 ? 492 ILE C CA  1 
ATOM   11327 C C   . ILE C 1 492 ? 122.570 146.597 201.985 1.00 100.00 ? 492 ILE C C   1 
ATOM   11328 O O   . ILE C 1 492 ? 122.238 146.374 203.156 1.00 100.00 ? 492 ILE C O   1 
ATOM   11329 C CB  . ILE C 1 492 ? 121.440 148.456 200.688 1.00 100.00 ? 492 ILE C CB  1 
ATOM   11330 C CG1 . ILE C 1 492 ? 121.506 149.945 200.355 1.00 100.00 ? 492 ILE C CG1 1 
ATOM   11331 C CG2 . ILE C 1 492 ? 120.182 148.145 201.482 1.00 100.00 ? 492 ILE C CG2 1 
ATOM   11332 C CD1 . ILE C 1 492 ? 120.446 150.397 199.374 1.00 100.00 ? 492 ILE C CD1 1 
ATOM   11333 N N   . TYR C 1 493 ? 122.845 145.610 201.133 1.00 100.35 ? 493 TYR C N   1 
ATOM   11334 C CA  . TYR C 1 493 ? 122.757 144.209 201.518 1.00 100.35 ? 493 TYR C CA  1 
ATOM   11335 C C   . TYR C 1 493 ? 124.126 143.595 201.781 1.00 100.35 ? 493 TYR C C   1 
ATOM   11336 O O   . TYR C 1 493 ? 124.243 142.368 201.867 1.00 100.35 ? 493 TYR C O   1 
ATOM   11337 C CB  . TYR C 1 493 ? 122.020 143.410 200.443 1.00 100.35 ? 493 TYR C CB  1 
ATOM   11338 C CG  . TYR C 1 493 ? 120.671 143.975 200.065 1.00 100.35 ? 493 TYR C CG  1 
ATOM   11339 C CD1 . TYR C 1 493 ? 119.538 143.671 200.806 1.00 100.35 ? 493 TYR C CD1 1 
ATOM   11340 C CD2 . TYR C 1 493 ? 120.528 144.806 198.962 1.00 100.35 ? 493 TYR C CD2 1 
ATOM   11341 C CE1 . TYR C 1 493 ? 118.303 144.182 200.465 1.00 100.35 ? 493 TYR C CE1 1 
ATOM   11342 C CE2 . TYR C 1 493 ? 119.297 145.322 198.612 1.00 100.35 ? 493 TYR C CE2 1 
ATOM   11343 C CZ  . TYR C 1 493 ? 118.188 145.007 199.367 1.00 100.35 ? 493 TYR C CZ  1 
ATOM   11344 O OH  . TYR C 1 493 ? 116.958 145.517 199.024 1.00 100.35 ? 493 TYR C OH  1 
ATOM   11345 N N   . ARG C 1 494 ? 125.166 144.421 201.909 1.00 101.22 ? 494 ARG C N   1 
ATOM   11346 C CA  . ARG C 1 494 ? 126.524 143.889 201.967 1.00 101.22 ? 494 ARG C CA  1 
ATOM   11347 C C   . ARG C 1 494 ? 126.746 143.056 203.226 1.00 101.22 ? 494 ARG C C   1 
ATOM   11348 O O   . ARG C 1 494 ? 126.958 141.839 203.149 1.00 101.22 ? 494 ARG C O   1 
ATOM   11349 C CB  . ARG C 1 494 ? 127.534 145.035 201.890 1.00 101.22 ? 494 ARG C CB  1 
ATOM   11350 C CG  . ARG C 1 494 ? 128.969 144.584 201.698 1.00 101.22 ? 494 ARG C CG  1 
ATOM   11351 C CD  . ARG C 1 494 ? 129.912 145.770 201.620 1.00 101.22 ? 494 ARG C CD  1 
ATOM   11352 N NE  . ARG C 1 494 ? 131.289 145.350 201.390 1.00 101.22 ? 494 ARG C NE  1 
ATOM   11353 C CZ  . ARG C 1 494 ? 131.805 145.097 200.196 1.00 101.22 ? 494 ARG C CZ  1 
ATOM   11354 N NH1 . ARG C 1 494 ? 131.088 145.226 199.092 1.00 101.22 ? 494 ARG C NH1 1 
ATOM   11355 N NH2 . ARG C 1 494 ? 133.072 144.703 200.107 1.00 101.22 ? 494 ARG C NH2 1 
ATOM   11356 N N   . ASP C 1 495 ? 126.658 143.693 204.398 1.00 103.11 ? 495 ASP C N   1 
ATOM   11357 C CA  . ASP C 1 495 ? 127.059 143.042 205.644 1.00 103.11 ? 495 ASP C CA  1 
ATOM   11358 C C   . ASP C 1 495 ? 126.315 141.731 205.849 1.00 103.11 ? 495 ASP C C   1 
ATOM   11359 O O   . ASP C 1 495 ? 126.929 140.688 206.110 1.00 103.11 ? 495 ASP C O   1 
ATOM   11360 C CB  . ASP C 1 495 ? 126.818 143.981 206.826 1.00 103.11 ? 495 ASP C CB  1 
ATOM   11361 C CG  . ASP C 1 495 ? 127.293 145.393 206.554 1.00 103.11 ? 495 ASP C CG  1 
ATOM   11362 O OD1 . ASP C 1 495 ? 128.492 145.571 206.250 1.00 103.11 ? 495 ASP C OD1 1 
ATOM   11363 O OD2 . ASP C 1 495 ? 126.466 146.324 206.645 1.00 103.11 ? 495 ASP C OD2 1 
ATOM   11364 N N   . GLU C 1 496 ? 124.988 141.763 205.703 1.00 102.32 ? 496 GLU C N   1 
ATOM   11365 C CA  . GLU C 1 496 ? 124.186 140.557 205.871 1.00 102.32 ? 496 GLU C CA  1 
ATOM   11366 C C   . GLU C 1 496 ? 124.698 139.434 204.979 1.00 102.32 ? 496 GLU C C   1 
ATOM   11367 O O   . GLU C 1 496 ? 124.897 138.302 205.437 1.00 102.32 ? 496 GLU C O   1 
ATOM   11368 C CB  . GLU C 1 496 ? 122.718 140.861 205.570 1.00 102.32 ? 496 GLU C CB  1 
ATOM   11369 C CG  . GLU C 1 496 ? 121.912 139.648 205.144 1.00 102.32 ? 496 GLU C CG  1 
ATOM   11370 C CD  . GLU C 1 496 ? 120.505 140.005 204.706 1.00 102.32 ? 496 GLU C CD  1 
ATOM   11371 O OE1 . GLU C 1 496 ? 120.186 141.211 204.643 1.00 102.32 ? 496 GLU C OE1 1 
ATOM   11372 O OE2 . GLU C 1 496 ? 119.717 139.078 204.424 1.00 102.32 ? 496 GLU C OE2 1 
ATOM   11373 N N   . ALA C 1 497 ? 124.957 139.742 203.706 1.00 102.34 ? 497 ALA C N   1 
ATOM   11374 C CA  . ALA C 1 497 ? 125.453 138.718 202.794 1.00 102.34 ? 497 ALA C CA  1 
ATOM   11375 C C   . ALA C 1 497 ? 126.787 138.166 203.273 1.00 102.34 ? 497 ALA C C   1 
ATOM   11376 O O   . ALA C 1 497 ? 127.021 136.952 203.221 1.00 102.34 ? 497 ALA C O   1 
ATOM   11377 C CB  . ALA C 1 497 ? 125.576 139.284 201.381 1.00 102.34 ? 497 ALA C CB  1 
ATOM   11378 N N   . LEU C 1 498 ? 127.664 139.039 203.775 1.00 102.61 ? 498 LEU C N   1 
ATOM   11379 C CA  . LEU C 1 498 ? 128.950 138.579 204.281 1.00 102.61 ? 498 LEU C CA  1 
ATOM   11380 C C   . LEU C 1 498 ? 128.794 137.647 205.472 1.00 102.61 ? 498 LEU C C   1 
ATOM   11381 O O   . LEU C 1 498 ? 129.690 136.839 205.733 1.00 102.61 ? 498 LEU C O   1 
ATOM   11382 C CB  . LEU C 1 498 ? 129.829 139.772 204.657 1.00 102.61 ? 498 LEU C CB  1 
ATOM   11383 C CG  . LEU C 1 498 ? 130.769 140.257 203.554 1.00 102.61 ? 498 LEU C CG  1 
ATOM   11384 C CD1 . LEU C 1 498 ? 131.852 141.157 204.122 1.00 102.61 ? 498 LEU C CD1 1 
ATOM   11385 C CD2 . LEU C 1 498 ? 131.380 139.074 202.821 1.00 102.61 ? 498 LEU C CD2 1 
ATOM   11386 N N   . ASN C 1 499 ? 127.679 137.739 206.199 1.00 103.45 ? 499 ASN C N   1 
ATOM   11387 C CA  . ASN C 1 499 ? 127.428 136.777 207.264 1.00 103.45 ? 499 ASN C CA  1 
ATOM   11388 C C   . ASN C 1 499 ? 126.948 135.444 206.703 1.00 103.45 ? 499 ASN C C   1 
ATOM   11389 O O   . ASN C 1 499 ? 127.275 134.384 207.249 1.00 103.45 ? 499 ASN C O   1 
ATOM   11390 C CB  . ASN C 1 499 ? 126.410 137.342 208.253 1.00 103.45 ? 499 ASN C CB  1 
ATOM   11391 C CG  . ASN C 1 499 ? 126.949 138.528 209.029 1.00 103.45 ? 499 ASN C CG  1 
ATOM   11392 O OD1 . ASN C 1 499 ? 128.157 138.655 209.227 1.00 103.45 ? 499 ASN C OD1 1 
ATOM   11393 N ND2 . ASN C 1 499 ? 126.055 139.404 209.469 1.00 103.45 ? 499 ASN C ND2 1 
ATOM   11394 N N   . ASN C 1 500 ? 126.176 135.478 205.615 1.00 102.34 ? 500 ASN C N   1 
ATOM   11395 C CA  . ASN C 1 500 ? 125.613 134.247 205.073 1.00 102.34 ? 500 ASN C CA  1 
ATOM   11396 C C   . ASN C 1 500 ? 126.655 133.431 204.319 1.00 102.34 ? 500 ASN C C   1 
ATOM   11397 O O   . ASN C 1 500 ? 126.627 132.196 204.359 1.00 102.34 ? 500 ASN C O   1 
ATOM   11398 C CB  . ASN C 1 500 ? 124.426 134.568 204.164 1.00 102.34 ? 500 ASN C CB  1 
ATOM   11399 C CG  . ASN C 1 500 ? 123.092 134.318 204.839 1.00 102.34 ? 500 ASN C CG  1 
ATOM   11400 O OD1 . ASN C 1 500 ? 122.973 133.450 205.704 1.00 102.34 ? 500 ASN C OD1 1 
ATOM   11401 N ND2 . ASN C 1 500 ? 122.078 135.079 204.446 1.00 102.34 ? 500 ASN C ND2 1 
ATOM   11402 N N   . ARG C 1 501 ? 127.580 134.099 203.629 1.00 101.71 ? 501 ARG C N   1 
ATOM   11403 C CA  . ARG C 1 501 ? 128.557 133.384 202.818 1.00 101.71 ? 501 ARG C CA  1 
ATOM   11404 C C   . ARG C 1 501 ? 129.618 132.693 203.666 1.00 101.71 ? 501 ARG C C   1 
ATOM   11405 O O   . ARG C 1 501 ? 129.995 131.555 203.368 1.00 101.71 ? 501 ARG C O   1 
ATOM   11406 C CB  . ARG C 1 501 ? 129.213 134.344 201.823 1.00 101.71 ? 501 ARG C CB  1 
ATOM   11407 C CG  . ARG C 1 501 ? 130.158 133.671 200.842 1.00 101.71 ? 501 ARG C CG  1 
ATOM   11408 C CD  . ARG C 1 501 ? 129.967 134.209 199.429 1.00 101.71 ? 501 ARG C CD  1 
ATOM   11409 N NE  . ARG C 1 501 ? 130.332 135.615 199.307 1.00 101.71 ? 501 ARG C NE  1 
ATOM   11410 C CZ  . ARG C 1 501 ? 131.317 136.067 198.544 1.00 101.71 ? 501 ARG C CZ  1 
ATOM   11411 N NH1 . ARG C 1 501 ? 132.059 135.248 197.816 1.00 101.71 ? 501 ARG C NH1 1 
ATOM   11412 N NH2 . ARG C 1 501 ? 131.562 137.373 198.506 1.00 101.71 ? 501 ARG C NH2 1 
ATOM   11413 N N   . PHE C 1 502 ? 130.099 133.347 204.717 1.00 103.39 ? 502 PHE C N   1 
ATOM   11414 C CA  . PHE C 1 502 ? 131.148 132.773 205.549 1.00 103.39 ? 502 PHE C CA  1 
ATOM   11415 C C   . PHE C 1 502 ? 130.609 132.388 206.923 1.00 103.39 ? 502 PHE C C   1 
ATOM   11416 O O   . PHE C 1 502 ? 130.902 131.306 207.432 1.00 103.39 ? 502 PHE C O   1 
ATOM   11417 C CB  . PHE C 1 502 ? 132.312 133.753 205.693 1.00 103.39 ? 502 PHE C CB  1 
ATOM   11418 C CG  . PHE C 1 502 ? 132.905 134.185 204.382 1.00 103.39 ? 502 PHE C CG  1 
ATOM   11419 C CD1 . PHE C 1 502 ? 132.975 133.307 203.313 1.00 103.39 ? 502 PHE C CD1 1 
ATOM   11420 C CD2 . PHE C 1 502 ? 133.390 135.471 204.217 1.00 103.39 ? 502 PHE C CD2 1 
ATOM   11421 C CE1 . PHE C 1 502 ? 133.519 133.703 202.105 1.00 103.39 ? 502 PHE C CE1 1 
ATOM   11422 C CE2 . PHE C 1 502 ? 133.934 135.873 203.012 1.00 103.39 ? 502 PHE C CE2 1 
ATOM   11423 C CZ  . PHE C 1 502 ? 133.998 134.988 201.955 1.00 103.39 ? 502 PHE C CZ  1 
HETATM 11424 C C1  . NAG D 2 .   ? 120.844 119.094 89.051  1.00 34.51  ? 1   NAG D C1  1 
HETATM 11425 C C2  . NAG D 2 .   ? 119.665 119.098 88.077  1.00 34.51  ? 1   NAG D C2  1 
HETATM 11426 C C3  . NAG D 2 .   ? 118.408 119.618 88.769  1.00 34.51  ? 1   NAG D C3  1 
HETATM 11427 C C4  . NAG D 2 .   ? 118.134 118.824 90.040  1.00 34.51  ? 1   NAG D C4  1 
HETATM 11428 C C5  . NAG D 2 .   ? 119.371 118.833 90.934  1.00 34.51  ? 1   NAG D C5  1 
HETATM 11429 C C6  . NAG D 2 .   ? 119.217 117.967 92.162  1.00 34.51  ? 1   NAG D C6  1 
HETATM 11430 C C7  . NAG D 2 .   ? 120.125 119.357 85.682  1.00 34.51  ? 1   NAG D C7  1 
HETATM 11431 C C8  . NAG D 2 .   ? 120.436 120.320 84.577  1.00 34.51  ? 1   NAG D C8  1 
HETATM 11432 N N2  . NAG D 2 .   ? 119.965 119.891 86.897  1.00 34.51  ? 1   NAG D N2  1 
HETATM 11433 O O3  . NAG D 2 .   ? 117.304 119.518 87.877  1.00 34.51  ? 1   NAG D O3  1 
HETATM 11434 O O4  . NAG D 2 .   ? 117.048 119.401 90.758  1.00 34.51  ? 1   NAG D O4  1 
HETATM 11435 O O5  . NAG D 2 .   ? 120.505 118.329 90.212  1.00 34.51  ? 1   NAG D O5  1 
HETATM 11436 O O6  . NAG D 2 .   ? 118.997 116.608 91.812  1.00 34.51  ? 1   NAG D O6  1 
HETATM 11437 O O7  . NAG D 2 .   ? 120.023 118.151 85.484  1.00 34.51  ? 1   NAG D O7  1 
HETATM 11438 C C1  . NAG D 2 .   ? 115.830 118.649 90.591  1.00 36.45  ? 2   NAG D C1  1 
HETATM 11439 C C2  . NAG D 2 .   ? 115.021 118.745 91.889  1.00 36.45  ? 2   NAG D C2  1 
HETATM 11440 C C3  . NAG D 2 .   ? 113.657 118.073 91.729  1.00 36.45  ? 2   NAG D C3  1 
HETATM 11441 C C4  . NAG D 2 .   ? 112.936 118.581 90.487  1.00 36.45  ? 2   NAG D C4  1 
HETATM 11442 C C5  . NAG D 2 .   ? 113.845 118.442 89.274  1.00 36.45  ? 2   NAG D C5  1 
HETATM 11443 C C6  . NAG D 2 .   ? 113.241 118.997 88.005  1.00 36.45  ? 2   NAG D C6  1 
HETATM 11444 C C7  . NAG D 2 .   ? 116.001 118.778 94.142  1.00 36.45  ? 2   NAG D C7  1 
HETATM 11445 C C8  . NAG D 2 .   ? 116.769 118.000 95.166  1.00 36.45  ? 2   NAG D C8  1 
HETATM 11446 N N2  . NAG D 2 .   ? 115.752 118.145 92.993  1.00 36.45  ? 2   NAG D N2  1 
HETATM 11447 O O3  . NAG D 2 .   ? 112.874 118.329 92.888  1.00 36.45  ? 2   NAG D O3  1 
HETATM 11448 O O4  . NAG D 2 .   ? 111.757 117.817 90.261  1.00 36.45  ? 2   NAG D O4  1 
HETATM 11449 O O5  . NAG D 2 .   ? 115.062 119.162 89.508  1.00 36.45  ? 2   NAG D O5  1 
HETATM 11450 O O6  . NAG D 2 .   ? 113.050 120.402 88.088  1.00 36.45  ? 2   NAG D O6  1 
HETATM 11451 O O7  . NAG D 2 .   ? 115.625 119.924 94.346  1.00 36.45  ? 2   NAG D O7  1 
HETATM 11452 C C1  . BMA D 2 .   ? 110.578 118.534 90.684  1.00 48.92  ? 3   BMA D C1  1 
HETATM 11453 C C2  . BMA D 2 .   ? 109.410 118.112 89.760  1.00 48.92  ? 3   BMA D C2  1 
HETATM 11454 C C3  . BMA D 2 .   ? 108.072 118.638 90.304  1.00 48.92  ? 3   BMA D C3  1 
HETATM 11455 C C4  . BMA D 2 .   ? 107.921 118.339 91.794  1.00 48.92  ? 3   BMA D C4  1 
HETATM 11456 C C5  . BMA D 2 .   ? 109.120 118.905 92.545  1.00 48.92  ? 3   BMA D C5  1 
HETATM 11457 C C6  . BMA D 2 .   ? 109.041 118.661 94.035  1.00 48.92  ? 3   BMA D C6  1 
HETATM 11458 O O2  . BMA D 2 .   ? 109.302 116.699 89.703  1.00 48.92  ? 3   BMA D O2  1 
HETATM 11459 O O3  . BMA D 2 .   ? 106.965 118.098 89.603  1.00 48.92  ? 3   BMA D O3  1 
HETATM 11460 O O4  . BMA D 2 .   ? 106.734 118.931 92.284  1.00 48.92  ? 3   BMA D O4  1 
HETATM 11461 O O5  . BMA D 2 .   ? 110.292 118.254 92.044  1.00 48.92  ? 3   BMA D O5  1 
HETATM 11462 O O6  . BMA D 2 .   ? 109.032 117.259 94.247  1.00 48.92  ? 3   BMA D O6  1 
HETATM 11463 C C1  . MAN D 2 .   ? 106.993 118.548 88.235  1.00 58.88  ? 4   MAN D C1  1 
HETATM 11464 C C2  . MAN D 2 .   ? 105.624 119.208 87.933  1.00 58.88  ? 4   MAN D C2  1 
HETATM 11465 C C3  . MAN D 2 .   ? 104.521 118.147 87.879  1.00 58.88  ? 4   MAN D C3  1 
HETATM 11466 C C4  . MAN D 2 .   ? 104.926 116.962 86.981  1.00 58.88  ? 4   MAN D C4  1 
HETATM 11467 C C5  . MAN D 2 .   ? 106.275 116.404 87.451  1.00 58.88  ? 4   MAN D C5  1 
HETATM 11468 C C6  . MAN D 2 .   ? 106.785 115.260 86.597  1.00 58.88  ? 4   MAN D C6  1 
HETATM 11469 O O2  . MAN D 2 .   ? 105.619 119.840 86.653  1.00 58.88  ? 4   MAN D O2  1 
HETATM 11470 O O3  . MAN D 2 .   ? 103.286 118.700 87.441  1.00 58.88  ? 4   MAN D O3  1 
HETATM 11471 O O4  . MAN D 2 .   ? 103.944 115.944 87.053  1.00 58.88  ? 4   MAN D O4  1 
HETATM 11472 O O5  . MAN D 2 .   ? 107.248 117.459 87.381  1.00 58.88  ? 4   MAN D O5  1 
HETATM 11473 O O6  . MAN D 2 .   ? 105.850 114.191 86.675  1.00 58.88  ? 4   MAN D O6  1 
HETATM 11474 C C1  . MAN D 2 .   ? 108.620 116.990 95.603  1.00 57.80  ? 5   MAN D C1  1 
HETATM 11475 C C2  . MAN D 2 .   ? 109.273 115.656 96.027  1.00 57.80  ? 5   MAN D C2  1 
HETATM 11476 C C3  . MAN D 2 .   ? 108.647 114.508 95.244  1.00 57.80  ? 5   MAN D C3  1 
HETATM 11477 C C4  . MAN D 2 .   ? 107.128 114.513 95.423  1.00 57.80  ? 5   MAN D C4  1 
HETATM 11478 C C5  . MAN D 2 .   ? 106.570 115.862 94.949  1.00 57.80  ? 5   MAN D C5  1 
HETATM 11479 C C6  . MAN D 2 .   ? 105.074 115.992 95.158  1.00 57.80  ? 5   MAN D C6  1 
HETATM 11480 O O2  . MAN D 2 .   ? 109.007 115.372 97.400  1.00 57.80  ? 5   MAN D O2  1 
HETATM 11481 O O3  . MAN D 2 .   ? 109.185 113.244 95.623  1.00 57.80  ? 5   MAN D O3  1 
HETATM 11482 O O4  . MAN D 2 .   ? 106.546 113.465 94.664  1.00 57.80  ? 5   MAN D O4  1 
HETATM 11483 O O5  . MAN D 2 .   ? 107.204 116.929 95.695  1.00 57.80  ? 5   MAN D O5  1 
HETATM 11484 O O6  . MAN D 2 .   ? 104.851 117.018 96.120  1.00 57.80  ? 5   MAN D O6  1 
HETATM 11485 C C1  . NAG E 3 .   ? 155.138 121.974 132.600 1.00 40.35  ? 1   NAG E C1  1 
HETATM 11486 C C2  . NAG E 3 .   ? 156.223 122.595 133.480 1.00 40.35  ? 1   NAG E C2  1 
HETATM 11487 C C3  . NAG E 3 .   ? 156.323 124.097 133.217 1.00 40.35  ? 1   NAG E C3  1 
HETATM 11488 C C4  . NAG E 3 .   ? 156.468 124.385 131.728 1.00 40.35  ? 1   NAG E C4  1 
HETATM 11489 C C5  . NAG E 3 .   ? 155.383 123.658 130.935 1.00 40.35  ? 1   NAG E C5  1 
HETATM 11490 C C6  . NAG E 3 .   ? 155.550 123.779 129.438 1.00 40.35  ? 1   NAG E C6  1 
HETATM 11491 C C7  . NAG E 3 .   ? 156.493 121.318 135.561 1.00 40.35  ? 1   NAG E C7  1 
HETATM 11492 C C8  . NAG E 3 .   ? 156.110 121.212 137.005 1.00 40.35  ? 1   NAG E C8  1 
HETATM 11493 N N2  . NAG E 3 .   ? 155.959 122.342 134.887 1.00 40.35  ? 1   NAG E N2  1 
HETATM 11494 O O3  . NAG E 3 .   ? 157.441 124.623 133.924 1.00 40.35  ? 1   NAG E O3  1 
HETATM 11495 O O4  . NAG E 3 .   ? 156.343 125.786 131.510 1.00 40.35  ? 1   NAG E O4  1 
HETATM 11496 O O5  . NAG E 3 .   ? 155.410 122.257 131.238 1.00 40.35  ? 1   NAG E O5  1 
HETATM 11497 O O6  . NAG E 3 .   ? 154.703 124.787 128.905 1.00 40.35  ? 1   NAG E O6  1 
HETATM 11498 O O7  . NAG E 3 .   ? 157.250 120.516 135.029 1.00 40.35  ? 1   NAG E O7  1 
HETATM 11499 C C1  . NAG E 3 .   ? 157.491 126.319 130.816 1.00 49.22  ? 2   NAG E C1  1 
HETATM 11500 C C2  . NAG E 3 .   ? 157.178 127.759 130.406 1.00 49.22  ? 2   NAG E C2  1 
HETATM 11501 C C3  . NAG E 3 .   ? 158.380 128.378 129.701 1.00 49.22  ? 2   NAG E C3  1 
HETATM 11502 C C4  . NAG E 3 .   ? 159.627 128.251 130.566 1.00 49.22  ? 2   NAG E C4  1 
HETATM 11503 C C5  . NAG E 3 .   ? 159.841 126.796 130.976 1.00 49.22  ? 2   NAG E C5  1 
HETATM 11504 C C6  . NAG E 3 .   ? 160.993 126.618 131.937 1.00 49.22  ? 2   NAG E C6  1 
HETATM 11505 C C7  . NAG E 3 .   ? 154.839 128.350 129.952 1.00 49.22  ? 2   NAG E C7  1 
HETATM 11506 C C8  . NAG E 3 .   ? 153.730 128.333 128.944 1.00 49.22  ? 2   NAG E C8  1 
HETATM 11507 N N2  . NAG E 3 .   ? 156.001 127.820 129.555 1.00 49.22  ? 2   NAG E N2  1 
HETATM 11508 O O3  . NAG E 3 .   ? 158.113 129.749 129.429 1.00 49.22  ? 2   NAG E O3  1 
HETATM 11509 O O4  . NAG E 3 .   ? 160.767 128.707 129.847 1.00 49.22  ? 2   NAG E O4  1 
HETATM 11510 O O5  . NAG E 3 .   ? 158.669 126.297 131.637 1.00 49.22  ? 2   NAG E O5  1 
HETATM 11511 O O6  . NAG E 3 .   ? 160.838 127.440 133.087 1.00 49.22  ? 2   NAG E O6  1 
HETATM 11512 O O7  . NAG E 3 .   ? 154.689 128.819 131.075 1.00 49.22  ? 2   NAG E O7  1 
HETATM 11513 C C1  . NAG F 2 .   ? 157.961 131.323 89.422  1.00 35.13  ? 1   NAG F C1  1 
HETATM 11514 C C2  . NAG F 2 .   ? 158.601 130.611 88.253  1.00 35.13  ? 1   NAG F C2  1 
HETATM 11515 C C3  . NAG F 2 .   ? 159.113 129.249 88.720  1.00 35.13  ? 1   NAG F C3  1 
HETATM 11516 C C4  . NAG F 2 .   ? 159.940 129.364 90.001  1.00 35.13  ? 1   NAG F C4  1 
HETATM 11517 C C5  . NAG F 2 .   ? 159.342 130.350 91.017  1.00 35.13  ? 1   NAG F C5  1 
HETATM 11518 C C6  . NAG F 2 .   ? 160.304 130.723 92.121  1.00 35.13  ? 1   NAG F C6  1 
HETATM 11519 C C7  . NAG F 2 .   ? 158.027 130.614 85.870  1.00 35.13  ? 1   NAG F C7  1 
HETATM 11520 C C8  . NAG F 2 .   ? 156.942 130.423 84.856  1.00 35.13  ? 1   NAG F C8  1 
HETATM 11521 N N2  . NAG F 2 .   ? 157.669 130.457 87.149  1.00 35.13  ? 1   NAG F N2  1 
HETATM 11522 O O3  . NAG F 2 .   ? 159.888 128.647 87.689  1.00 35.13  ? 1   NAG F O3  1 
HETATM 11523 O O4  . NAG F 2 .   ? 159.962 128.094 90.644  1.00 35.13  ? 1   NAG F O4  1 
HETATM 11524 O O5  . NAG F 2 .   ? 158.928 131.575 90.393  1.00 35.13  ? 1   NAG F O5  1 
HETATM 11525 O O6  . NAG F 2 .   ? 161.624 130.900 91.627  1.00 35.13  ? 1   NAG F O6  1 
HETATM 11526 O O7  . NAG F 2 .   ? 159.175 130.900 85.547  1.00 35.13  ? 1   NAG F O7  1 
HETATM 11527 C C1  . NAG F 2 .   ? 161.193 127.359 90.500  1.00 36.98  ? 2   NAG F C1  1 
HETATM 11528 C C2  . NAG F 2 .   ? 161.458 126.600 91.805  1.00 36.98  ? 2   NAG F C2  1 
HETATM 11529 C C3  . NAG F 2 .   ? 162.689 125.702 91.668  1.00 36.98  ? 2   NAG F C3  1 
HETATM 11530 C C4  . NAG F 2 .   ? 162.598 124.826 90.425  1.00 36.98  ? 2   NAG F C4  1 
HETATM 11531 C C5  . NAG F 2 .   ? 162.306 125.691 89.205  1.00 36.98  ? 2   NAG F C5  1 
HETATM 11532 C C6  . NAG F 2 .   ? 162.103 124.890 87.940  1.00 36.98  ? 2   NAG F C6  1 
HETATM 11533 C C7  . NAG F 2 .   ? 160.982 127.404 94.078  1.00 36.98  ? 2   NAG F C7  1 
HETATM 11534 C C8  . NAG F 2 .   ? 161.286 128.448 95.108  1.00 36.98  ? 2   NAG F C8  1 
HETATM 11535 N N2  . NAG F 2 .   ? 161.627 127.524 92.914  1.00 36.98  ? 2   NAG F N2  1 
HETATM 11536 O O3  . NAG F 2 .   ? 162.802 124.887 92.829  1.00 36.98  ? 2   NAG F O3  1 
HETATM 11537 O O4  . NAG F 2 .   ? 163.837 124.159 90.213  1.00 36.98  ? 2   NAG F O4  1 
HETATM 11538 O O5  . NAG F 2 .   ? 161.104 126.440 89.422  1.00 36.98  ? 2   NAG F O5  1 
HETATM 11539 O O6  . NAG F 2 .   ? 161.039 123.959 88.079  1.00 36.98  ? 2   NAG F O6  1 
HETATM 11540 O O7  . NAG F 2 .   ? 160.188 126.497 94.288  1.00 36.98  ? 2   NAG F O7  1 
HETATM 11541 C C1  . BMA F 2 .   ? 163.803 122.782 90.645  1.00 48.75  ? 3   BMA F C1  1 
HETATM 11542 C C2  . BMA F 2 .   ? 164.764 121.983 89.729  1.00 48.75  ? 3   BMA F C2  1 
HETATM 11543 C C3  . BMA F 2 .   ? 165.003 120.572 90.284  1.00 48.75  ? 3   BMA F C3  1 
HETATM 11544 C C4  . BMA F 2 .   ? 165.346 120.614 91.770  1.00 48.75  ? 3   BMA F C4  1 
HETATM 11545 C C5  . BMA F 2 .   ? 164.239 121.344 92.521  1.00 48.75  ? 3   BMA F C5  1 
HETATM 11546 C C6  . BMA F 2 .   ? 164.506 121.418 94.008  1.00 48.75  ? 3   BMA F C6  1 
HETATM 11547 O O2  . BMA F 2 .   ? 166.033 122.616 89.663  1.00 48.75  ? 3   BMA F O2  1 
HETATM 11548 O O3  . BMA F 2 .   ? 166.039 119.896 89.590  1.00 48.75  ? 3   BMA F O3  1 
HETATM 11549 O O4  . BMA F 2 .   ? 165.472 119.298 92.272  1.00 48.75  ? 3   BMA F O4  1 
HETATM 11550 O O5  . BMA F 2 .   ? 164.172 122.681 92.011  1.00 48.75  ? 3   BMA F O5  1 
HETATM 11551 O O6  . BMA F 2 .   ? 165.774 122.028 94.194  1.00 48.75  ? 3   BMA F O6  1 
HETATM 11552 C C1  . MAN F 2 .   ? 165.655 119.691 88.216  1.00 58.84  ? 4   MAN F C1  1 
HETATM 11553 C C2  . MAN F 2 .   ? 165.764 118.174 87.924  1.00 58.84  ? 4   MAN F C2  1 
HETATM 11554 C C3  . MAN F 2 .   ? 167.232 117.741 87.893  1.00 58.84  ? 4   MAN F C3  1 
HETATM 11555 C C4  . MAN F 2 .   ? 168.069 118.671 86.994  1.00 58.84  ? 4   MAN F C4  1 
HETATM 11556 C C5  . MAN F 2 .   ? 167.887 120.122 87.454  1.00 58.84  ? 4   MAN F C5  1 
HETATM 11557 C C6  . MAN F 2 .   ? 168.639 121.124 86.601  1.00 58.84  ? 4   MAN F C6  1 
HETATM 11558 O O2  . MAN F 2 .   ? 165.237 117.850 86.637  1.00 58.84  ? 4   MAN F O2  1 
HETATM 11559 O O3  . MAN F 2 .   ? 167.372 116.390 87.471  1.00 58.84  ? 4   MAN F O3  1 
HETATM 11560 O O4  . MAN F 2 .   ? 169.438 118.318 87.077  1.00 58.84  ? 4   MAN F O4  1 
HETATM 11561 O O5  . MAN F 2 .   ? 166.489 120.450 87.371  1.00 58.84  ? 4   MAN F O5  1 
HETATM 11562 O O6  . MAN F 2 .   ? 170.000 120.718 86.527  1.00 58.84  ? 4   MAN F O6  1 
HETATM 11563 C C1  . MAN F 2 .   ? 166.212 121.810 95.551  1.00 57.21  ? 5   MAN F C1  1 
HETATM 11564 C C2  . MAN F 2 .   ? 167.082 123.026 95.960  1.00 57.21  ? 5   MAN F C2  1 
HETATM 11565 C C3  . MAN F 2 .   ? 168.409 122.992 95.206  1.00 57.21  ? 5   MAN F C3  1 
HETATM 11566 C C4  . MAN F 2 .   ? 169.103 121.646 95.416  1.00 57.21  ? 5   MAN F C4  1 
HETATM 11567 C C5  . MAN F 2 .   ? 168.179 120.526 94.926  1.00 57.21  ? 5   MAN F C5  1 
HETATM 11568 C C6  . MAN F 2 .   ? 168.761 119.142 95.137  1.00 57.21  ? 5   MAN F C6  1 
HETATM 11569 O O2  . MAN F 2 .   ? 167.426 122.969 97.344  1.00 57.21  ? 5   MAN F O2  1 
HETATM 11570 O O3  . MAN F 2 .   ? 169.271 124.057 95.595  1.00 57.21  ? 5   MAN F O3  1 
HETATM 11571 O O4  . MAN F 2 .   ? 170.320 121.609 94.688  1.00 57.21  ? 5   MAN F O4  1 
HETATM 11572 O O5  . MAN F 2 .   ? 166.932 120.589 95.660  1.00 57.21  ? 5   MAN F O5  1 
HETATM 11573 O O6  . MAN F 2 .   ? 168.060 118.526 96.212  1.00 57.21  ? 5   MAN F O6  1 
HETATM 11574 C C1  . NAG G 3 .   ? 138.611 159.594 132.605 1.00 39.74  ? 1   NAG G C1  1 
HETATM 11575 C C2  . NAG G 3 .   ? 137.523 160.229 133.470 1.00 39.74  ? 1   NAG G C2  1 
HETATM 11576 C C3  . NAG G 3 .   ? 136.178 159.552 133.210 1.00 39.74  ? 1   NAG G C3  1 
HETATM 11577 C C4  . NAG G 3 .   ? 135.864 159.515 131.720 1.00 39.74  ? 1   NAG G C4  1 
HETATM 11578 C C5  . NAG G 3 .   ? 137.042 158.935 130.939 1.00 39.74  ? 1   NAG G C5  1 
HETATM 11579 C C6  . NAG G 3 .   ? 136.859 159.000 129.441 1.00 39.74  ? 1   NAG G C6  1 
HETATM 11580 C C7  . NAG G 3 .   ? 138.486 161.136 135.540 1.00 39.74  ? 1   NAG G C7  1 
HETATM 11581 C C8  . NAG G 3 .   ? 138.761 160.883 136.990 1.00 39.74  ? 1   NAG G C8  1 
HETATM 11582 N N2  . NAG G 3 .   ? 137.866 160.152 134.881 1.00 39.74  ? 1   NAG G N2  1 
HETATM 11583 O O3  . NAG G 3 .   ? 135.156 160.258 133.904 1.00 39.74  ? 1   NAG G O3  1 
HETATM 11584 O O4  . NAG G 3 .   ? 134.716 158.702 131.502 1.00 39.74  ? 1   NAG G O4  1 
HETATM 11585 O O5  . NAG G 3 .   ? 138.237 159.668 131.239 1.00 39.74  ? 1   NAG G O5  1 
HETATM 11586 O O6  . NAG G 3 .   ? 136.186 157.849 128.952 1.00 39.74  ? 1   NAG G O6  1 
HETATM 11587 O O7  . NAG G 3 .   ? 138.810 162.182 134.990 1.00 39.74  ? 1   NAG G O7  1 
HETATM 11588 C C1  . NAG G 3 .   ? 133.683 159.439 130.814 1.00 48.20  ? 2   NAG G C1  1 
HETATM 11589 C C2  . NAG G 3 .   ? 132.588 158.459 130.387 1.00 48.20  ? 2   NAG G C2  1 
HETATM 11590 C C3  . NAG G 3 .   ? 131.454 159.207 129.692 1.00 48.20  ? 2   NAG G C3  1 
HETATM 11591 C C4  . NAG G 3 .   ? 130.949 160.343 130.571 1.00 48.20  ? 2   NAG G C4  1 
HETATM 11592 C C5  . NAG G 3 .   ? 132.107 161.241 130.995 1.00 48.20  ? 2   NAG G C5  1 
HETATM 11593 C C6  . NAG G 3 .   ? 131.692 162.320 131.968 1.00 48.20  ? 2   NAG G C6  1 
HETATM 11594 C C7  . NAG G 3 .   ? 133.265 156.148 129.904 1.00 48.20  ? 2   NAG G C7  1 
HETATM 11595 C C8  . NAG G 3 .   ? 133.828 155.211 128.878 1.00 48.20  ? 2   NAG G C8  1 
HETATM 11596 N N2  . NAG G 3 .   ? 133.121 157.420 129.519 1.00 48.20  ? 2   NAG G N2  1 
HETATM 11597 O O3  . NAG G 3 .   ? 130.394 158.301 129.409 1.00 48.20  ? 2   NAG G O3  1 
HETATM 11598 O O4  . NAG G 3 .   ? 129.991 161.119 129.861 1.00 48.20  ? 2   NAG G O4  1 
HETATM 11599 O O5  . NAG G 3 .   ? 133.117 160.459 131.649 1.00 48.20  ? 2   NAG G O5  1 
HETATM 11600 O O6  . NAG G 3 .   ? 130.905 161.789 133.025 1.00 48.20  ? 2   NAG G O6  1 
HETATM 11601 O O7  . NAG G 3 .   ? 132.956 155.770 131.029 1.00 48.20  ? 2   NAG G O7  1 
HETATM 11602 C C1  . NAG H 2 .   ? 128.892 157.575 89.098  1.00 33.59  ? 1   NAG H C1  1 
HETATM 11603 C C2  . NAG H 2 .   ? 129.486 158.597 88.132  1.00 33.59  ? 1   NAG H C2  1 
HETATM 11604 C C3  . NAG H 2 .   ? 130.549 159.433 88.837  1.00 33.59  ? 1   NAG H C3  1 
HETATM 11605 C C4  . NAG H 2 .   ? 129.975 160.070 90.096  1.00 33.59  ? 1   NAG H C4  1 
HETATM 11606 C C5  . NAG H 2 .   ? 129.342 159.001 90.984  1.00 33.59  ? 1   NAG H C5  1 
HETATM 11607 C C6  . NAG H 2 .   ? 128.624 159.580 92.181  1.00 33.59  ? 1   NAG H C6  1 
HETATM 11608 C C7  . NAG H 2 .   ? 129.491 158.057 85.741  1.00 33.59  ? 1   NAG H C7  1 
HETATM 11609 C C8  . NAG H 2 .   ? 130.186 157.319 84.638  1.00 33.59  ? 1   NAG H C8  1 
HETATM 11610 N N2  . NAG H 2 .   ? 130.040 157.948 86.955  1.00 33.59  ? 1   NAG H N2  1 
HETATM 11611 O O3  . NAG H 2 .   ? 131.022 160.438 87.947  1.00 33.59  ? 1   NAG H O3  1 
HETATM 11612 O O4  . NAG H 2 .   ? 131.004 160.720 90.835  1.00 33.59  ? 1   NAG H O4  1 
HETATM 11613 O O5  . NAG H 2 .   ? 128.367 158.248 90.244  1.00 33.59  ? 1   NAG H O5  1 
HETATM 11614 O O6  . NAG H 2 .   ? 127.741 160.625 91.800  1.00 33.59  ? 1   NAG H O6  1 
HETATM 11615 O O7  . NAG H 2 .   ? 128.479 158.720 85.542  1.00 33.59  ? 1   NAG H O7  1 
HETATM 11616 C C1  . NAG H 2 .   ? 130.991 162.148 90.644  1.00 36.12  ? 2   NAG H C1  1 
HETATM 11617 C C2  . NAG H 2 .   ? 131.519 162.814 91.918  1.00 36.12  ? 2   NAG H C2  1 
HETATM 11618 C C3  . NAG H 2 .   ? 131.654 164.327 91.724  1.00 36.12  ? 2   NAG H C3  1 
HETATM 11619 C C4  . NAG H 2 .   ? 132.424 164.655 90.451  1.00 36.12  ? 2   NAG H C4  1 
HETATM 11620 C C5  . NAG H 2 .   ? 131.814 163.910 89.270  1.00 36.12  ? 2   NAG H C5  1 
HETATM 11621 C C6  . NAG H 2 .   ? 132.578 164.103 87.980  1.00 36.12  ? 2   NAG H C6  1 
HETATM 11622 C C7  . NAG H 2 .   ? 131.046 161.870 94.137  1.00 36.12  ? 2   NAG H C7  1 
HETATM 11623 C C8  . NAG H 2 .   ? 130.007 161.663 95.195  1.00 36.12  ? 2   NAG H C8  1 
HETATM 11624 N N2  . NAG H 2 .   ? 130.646 162.525 93.044  1.00 36.12  ? 2   NAG H N2  1 
HETATM 11625 O O3  . NAG H 2 .   ? 132.319 164.883 92.851  1.00 36.12  ? 2   NAG H O3  1 
HETATM 11626 O O4  . NAG H 2 .   ? 132.350 166.052 90.186  1.00 36.12  ? 2   NAG H O4  1 
HETATM 11627 O O5  . NAG H 2 .   ? 131.809 162.504 89.544  1.00 36.12  ? 2   NAG H O5  1 
HETATM 11628 O O6  . NAG H 2 .   ? 133.976 163.948 88.174  1.00 36.12  ? 2   NAG H O6  1 
HETATM 11629 O O7  . NAG H 2 .   ? 132.193 161.462 94.265  1.00 36.12  ? 2   NAG H O7  1 
HETATM 11630 C C1  . BMA H 2 .   ? 133.550 166.738 90.603  1.00 48.19  ? 3   BMA H C1  1 
HETATM 11631 C C2  . BMA H 2 .   ? 133.729 167.976 89.690  1.00 48.19  ? 3   BMA H C2  1 
HETATM 11632 C C3  . BMA H 2 .   ? 134.845 168.886 90.226  1.00 48.19  ? 3   BMA H C3  1 
HETATM 11633 C C4  . BMA H 2 .   ? 134.679 169.149 91.722  1.00 48.19  ? 3   BMA H C4  1 
HETATM 11634 C C5  . BMA H 2 .   ? 134.600 167.819 92.463  1.00 48.19  ? 3   BMA H C5  1 
HETATM 11635 C C6  . BMA H 2 .   ? 134.435 167.996 93.955  1.00 48.19  ? 3   BMA H C6  1 
HETATM 11636 O O2  . BMA H 2 .   ? 132.543 168.755 89.666  1.00 48.19  ? 3   BMA H O2  1 
HETATM 11637 O O3  . BMA H 2 .   ? 134.895 170.125 89.538  1.00 48.19  ? 3   BMA H O3  1 
HETATM 11638 O O4  . BMA H 2 .   ? 135.780 169.896 92.204  1.00 48.19  ? 3   BMA H O4  1 
HETATM 11639 O O5  . BMA H 2 .   ? 133.459 167.110 91.967  1.00 48.19  ? 3   BMA H O5  1 
HETATM 11640 O O6  . BMA H 2 .   ? 133.250 168.742 94.175  1.00 48.19  ? 3   BMA H O6  1 
HETATM 11641 C C1  . MAN H 2 .   ? 135.232 169.898 88.155  1.00 57.74  ? 4   MAN H C1  1 
HETATM 11642 C C2  . MAN H 2 .   ? 136.548 170.663 87.867  1.00 57.74  ? 4   MAN H C2  1 
HETATM 11643 C C3  . MAN H 2 .   ? 136.298 172.173 87.882  1.00 57.74  ? 4   MAN H C3  1 
HETATM 11644 C C4  . MAN H 2 .   ? 135.090 172.547 87.002  1.00 57.74  ? 4   MAN H C4  1 
HETATM 11645 C C5  . MAN H 2 .   ? 133.865 171.737 87.448  1.00 57.74  ? 4   MAN H C5  1 
HETATM 11646 C C6  . MAN H 2 .   ? 132.631 172.001 86.608  1.00 57.74  ? 4   MAN H C6  1 
HETATM 11647 O O2  . MAN H 2 .   ? 137.048 170.367 86.564  1.00 57.74  ? 4   MAN H O2  1 
HETATM 11648 O O3  . MAN H 2 .   ? 137.451 172.899 87.474  1.00 57.74  ? 4   MAN H O3  1 
HETATM 11649 O O4  . MAN H 2 .   ? 134.811 173.929 87.127  1.00 57.74  ? 4   MAN H O4  1 
HETATM 11650 O O5  . MAN H 2 .   ? 134.177 170.338 87.331  1.00 57.74  ? 4   MAN H O5  1 
HETATM 11651 O O6  . MAN H 2 .   ? 132.316 173.384 86.698  1.00 57.74  ? 4   MAN H O6  1 
HETATM 11652 C C1  . MAN H 2 .   ? 133.229 169.205 95.541  1.00 56.57  ? 5   MAN H C1  1 
HETATM 11653 C C2  . MAN H 2 .   ? 131.750 169.266 95.982  1.00 56.57  ? 5   MAN H C2  1 
HETATM 11654 C C3  . MAN H 2 .   ? 131.036 170.377 95.222  1.00 56.57  ? 5   MAN H C3  1 
HETATM 11655 C C4  . MAN H 2 .   ? 131.770 171.705 95.420  1.00 56.57  ? 5   MAN H C4  1 
HETATM 11656 C C5  . MAN H 2 .   ? 133.218 171.558 94.932  1.00 56.57  ? 5   MAN H C5  1 
HETATM 11657 C C6  . MAN H 2 .   ? 134.049 172.806 95.157  1.00 56.57  ? 5   MAN H C6  1 
HETATM 11658 O O2  . MAN H 2 .   ? 131.644 169.618 97.361  1.00 56.57  ? 5   MAN H O2  1 
HETATM 11659 O O3  . MAN H 2 .   ? 129.671 170.503 95.611  1.00 56.57  ? 5   MAN H O3  1 
HETATM 11660 O O4  . MAN H 2 .   ? 131.123 172.732 94.687  1.00 56.57  ? 5   MAN H O4  1 
HETATM 11661 O O5  . MAN H 2 .   ? 133.857 170.474 95.652  1.00 56.57  ? 5   MAN H O5  1 
HETATM 11662 O O6  . MAN H 2 .   ? 135.067 172.495 96.103  1.00 56.57  ? 5   MAN H O6  1 
HETATM 11663 C C1  . NAG I 3 .   ? 114.240 126.473 132.600 1.00 40.47  ? 1   NAG I C1  1 
HETATM 11664 C C2  . NAG I 3 .   ? 114.240 125.223 133.478 1.00 40.47  ? 1   NAG I C2  1 
HETATM 11665 C C3  . NAG I 3 .   ? 115.498 124.395 133.219 1.00 40.47  ? 1   NAG I C3  1 
HETATM 11666 C C4  . NAG I 3 .   ? 115.674 124.120 131.731 1.00 40.47  ? 1   NAG I C4  1 
HETATM 11667 C C5  . NAG I 3 .   ? 115.581 125.419 130.932 1.00 40.47  ? 1   NAG I C5  1 
HETATM 11668 C C6  . NAG I 3 .   ? 115.594 125.204 129.436 1.00 40.47  ? 1   NAG I C6  1 
HETATM 11669 C C7  . NAG I 3 .   ? 112.987 125.611 135.555 1.00 40.47  ? 1   NAG I C7  1 
HETATM 11670 C C8  . NAG I 3 .   ? 113.076 125.994 137.000 1.00 40.47  ? 1   NAG I C8  1 
HETATM 11671 N N2  . NAG I 3 .   ? 114.144 125.575 134.886 1.00 40.47  ? 1   NAG I N2  1 
HETATM 11672 O O3  . NAG I 3 .   ? 115.406 123.167 133.932 1.00 40.47  ? 1   NAG I O3  1 
HETATM 11673 O O4  . NAG I 3 .   ? 116.951 123.530 131.512 1.00 40.47  ? 1   NAG I O4  1 
HETATM 11674 O O5  . NAG I 3 .   ? 114.354 126.097 131.236 1.00 40.47  ? 1   NAG I O5  1 
HETATM 11675 O O6  . NAG I 3 .   ? 116.912 125.285 128.915 1.00 40.47  ? 1   NAG I O6  1 
HETATM 11676 O O7  . NAG I 3 .   ? 111.918 125.346 135.018 1.00 40.47  ? 1   NAG I O7  1 
HETATM 11677 C C1  . NAG I 3 .   ? 116.841 122.257 130.838 1.00 49.14  ? 2   NAG I C1  1 
HETATM 11678 C C2  . NAG I 3 .   ? 118.244 121.807 130.421 1.00 49.14  ? 2   NAG I C2  1 
HETATM 11679 C C3  . NAG I 3 .   ? 118.180 120.442 129.743 1.00 49.14  ? 2   NAG I C3  1 
HETATM 11680 C C4  . NAG I 3 .   ? 117.460 119.439 130.635 1.00 49.14  ? 2   NAG I C4  1 
HETATM 11681 C C5  . NAG I 3 .   ? 116.093 119.981 131.041 1.00 49.14  ? 2   NAG I C5  1 
HETATM 11682 C C6  . NAG I 3 .   ? 115.369 119.086 132.019 1.00 49.14  ? 2   NAG I C6  1 
HETATM 11683 C C7  . NAG I 3 .   ? 119.911 123.537 129.913 1.00 49.14  ? 2   NAG I C7  1 
HETATM 11684 C C8  . NAG I 3 .   ? 120.432 124.489 128.880 1.00 49.14  ? 2   NAG I C8  1 
HETATM 11685 N N2  . NAG I 3 .   ? 118.870 122.783 129.544 1.00 49.14  ? 2   NAG I N2  1 
HETATM 11686 O O3  . NAG I 3 .   ? 119.499 119.988 129.466 1.00 49.14  ? 2   NAG I O3  1 
HETATM 11687 O O4  . NAG I 3 .   ? 117.292 118.205 129.946 1.00 49.14  ? 2   NAG I O4  1 
HETATM 11688 O O5  . NAG I 3 .   ? 116.244 121.258 131.680 1.00 49.14  ? 2   NAG I O5  1 
HETATM 11689 O O6  . NAG I 3 .   ? 116.152 118.851 133.182 1.00 49.14  ? 2   NAG I O6  1 
HETATM 11690 O O7  . NAG I 3 .   ? 120.408 123.456 131.031 1.00 49.14  ? 2   NAG I O7  1 
HETATM 11691 C C1  . GAL J 4 .   ? 155.550 117.426 85.238  1.00 39.74  ? 1   GAL J C1  1 
HETATM 11692 C C2  . GAL J 4 .   ? 155.166 116.566 86.453  1.00 39.74  ? 1   GAL J C2  1 
HETATM 11693 C C3  . GAL J 4 .   ? 153.706 116.806 86.824  1.00 39.74  ? 1   GAL J C3  1 
HETATM 11694 C C4  . GAL J 4 .   ? 153.481 118.300 87.094  1.00 39.74  ? 1   GAL J C4  1 
HETATM 11695 C C5  . GAL J 4 .   ? 153.961 119.109 85.887  1.00 39.74  ? 1   GAL J C5  1 
HETATM 11696 C C6  . GAL J 4 .   ? 153.937 120.617 86.096  1.00 39.74  ? 1   GAL J C6  1 
HETATM 11697 O O1  . GAL J 4 .   ? 156.898 117.267 84.910  1.00 39.74  ? 1   GAL J O1  1 
HETATM 11698 O O2  . GAL J 4 .   ? 155.318 115.182 86.189  1.00 39.74  ? 1   GAL J O2  1 
HETATM 11699 O O3  . GAL J 4 .   ? 153.328 116.086 87.997  1.00 39.74  ? 1   GAL J O3  1 
HETATM 11700 O O4  . GAL J 4 .   ? 154.178 118.707 88.260  1.00 39.74  ? 1   GAL J O4  1 
HETATM 11701 O O5  . GAL J 4 .   ? 155.321 118.793 85.536  1.00 39.74  ? 1   GAL J O5  1 
HETATM 11702 O O6  . GAL J 4 .   ? 154.090 121.306 84.871  1.00 39.74  ? 1   GAL J O6  1 
HETATM 11703 C C1  . SIA J 4 .   ? 152.445 114.985 90.027  1.00 33.88  ? 2   SIA J C1  1 
HETATM 11704 C C2  . SIA J 4 .   ? 152.234 115.439 88.520  1.00 33.88  ? 2   SIA J C2  1 
HETATM 11705 C C3  . SIA J 4 .   ? 151.873 114.312 87.547  1.00 33.88  ? 2   SIA J C3  1 
HETATM 11706 C C4  . SIA J 4 .   ? 150.470 113.751 87.769  1.00 33.88  ? 2   SIA J C4  1 
HETATM 11707 C C5  . SIA J 4 .   ? 149.420 114.865 87.717  1.00 33.88  ? 2   SIA J C5  1 
HETATM 11708 C C6  . SIA J 4 .   ? 149.824 116.066 88.612  1.00 33.88  ? 2   SIA J C6  1 
HETATM 11709 C C7  . SIA J 4 .   ? 149.001 117.343 88.303  1.00 33.88  ? 2   SIA J C7  1 
HETATM 11710 C C8  . SIA J 4 .   ? 149.600 118.584 89.003  1.00 33.88  ? 2   SIA J C8  1 
HETATM 11711 C C9  . SIA J 4 .   ? 148.638 119.766 88.963  1.00 33.88  ? 2   SIA J C9  1 
HETATM 11712 C C10 . SIA J 4 .   ? 146.915 114.697 87.704  1.00 33.88  ? 2   SIA J C10 1 
HETATM 11713 C C11 . SIA J 4 .   ? 145.738 114.018 88.400  1.00 33.88  ? 2   SIA J C11 1 
HETATM 11714 N N5  . SIA J 4 .   ? 148.135 114.362 88.193  1.00 33.88  ? 2   SIA J N5  1 
HETATM 11715 O O1A . SIA J 4 .   ? 151.945 115.784 90.865  1.00 33.88  ? 2   SIA J O1A 1 
HETATM 11716 O O1B . SIA J 4 .   ? 153.062 113.918 90.231  1.00 33.88  ? 2   SIA J O1B 1 
HETATM 11717 O O4  . SIA J 4 .   ? 150.117 112.770 86.778  1.00 33.88  ? 2   SIA J O4  1 
HETATM 11718 O O6  . SIA J 4 .   ? 151.180 116.460 88.431  1.00 33.88  ? 2   SIA J O6  1 
HETATM 11719 O O7  . SIA J 4 .   ? 148.884 117.518 86.897  1.00 33.88  ? 2   SIA J O7  1 
HETATM 11720 O O8  . SIA J 4 .   ? 149.967 118.248 90.339  1.00 33.88  ? 2   SIA J O8  1 
HETATM 11721 O O9  . SIA J 4 .   ? 149.275 120.928 89.491  1.00 33.88  ? 2   SIA J O9  1 
HETATM 11722 O O10 . SIA J 4 .   ? 146.733 115.479 86.775  1.00 33.88  ? 2   SIA J O10 1 
HETATM 11723 C C1  . GAL K 4 .   ? 110.125 128.250 85.282  1.00 40.34  ? 1   GAL K C1  1 
HETATM 11724 C C2  . GAL K 4 .   ? 109.580 129.084 86.455  1.00 40.34  ? 1   GAL K C2  1 
HETATM 11725 C C3  . GAL K 4 .   ? 110.526 130.241 86.766  1.00 40.34  ? 1   GAL K C3  1 
HETATM 11726 C C4  . GAL K 4 .   ? 111.935 129.702 87.046  1.00 40.34  ? 1   GAL K C4  1 
HETATM 11727 C C5  . GAL K 4 .   ? 112.381 128.821 85.877  1.00 40.34  ? 1   GAL K C5  1 
HETATM 11728 C C6  . GAL K 4 .   ? 113.702 128.102 86.107  1.00 40.34  ? 1   GAL K C6  1 
HETATM 11729 O O1  . GAL K 4 .   ? 109.313 127.142 85.025  1.00 40.34  ? 1   GAL K O1  1 
HETATM 11730 O O2  . GAL K 4 .   ? 108.311 129.641 86.162  1.00 40.34  ? 1   GAL K O2  1 
HETATM 11731 O O3  . GAL K 4 .   ? 110.105 130.977 87.915  1.00 40.34  ? 1   GAL K O3  1 
HETATM 11732 O O4  . GAL K 4 .   ? 111.953 128.956 88.251  1.00 40.34  ? 1   GAL K O4  1 
HETATM 11733 O O5  . GAL K 4 .   ? 111.426 127.783 85.595  1.00 40.34  ? 1   GAL K O5  1 
HETATM 11734 O O6  . GAL K 4 .   ? 114.169 127.500 84.917  1.00 40.34  ? 1   GAL K O6  1 
HETATM 11735 C C1  . SIA K 4 .   ? 109.575 132.251 90.026  1.00 34.11  ? 2   SIA K C1  1 
HETATM 11736 C C2  . SIA K 4 .   ? 110.082 132.210 88.521  1.00 34.11  ? 2   SIA K C2  1 
HETATM 11737 C C3  . SIA K 4 .   ? 109.300 133.099 87.550  1.00 34.11  ? 2   SIA K C3  1 
HETATM 11738 C C4  . SIA K 4 .   ? 109.530 134.590 87.783  1.00 34.11  ? 2   SIA K C4  1 
HETATM 11739 C C5  . SIA K 4 .   ? 111.024 134.926 87.729  1.00 34.11  ? 2   SIA K C5  1 
HETATM 11740 C C6  . SIA K 4 .   ? 111.854 133.961 88.619  1.00 34.11  ? 2   SIA K C6  1 
HETATM 11741 C C7  . SIA K 4 .   ? 113.370 134.022 88.304  1.00 34.11  ? 2   SIA K C7  1 
HETATM 11742 C C8  . SIA K 4 .   ? 114.149 132.868 88.978  1.00 34.11  ? 2   SIA K C8  1 
HETATM 11743 C C9  . SIA K 4 .   ? 115.644 133.155 88.982  1.00 34.11  ? 2   SIA K C9  1 
HETATM 11744 C C10 . SIA K 4 .   ? 112.146 137.168 87.701  1.00 34.11  ? 2   SIA K C10 1 
HETATM 11745 C C11 . SIA K 4 .   ? 112.179 138.525 88.400  1.00 34.11  ? 2   SIA K C11 1 
HETATM 11746 N N5  . SIA K 4 .   ? 111.250 136.286 88.209  1.00 34.11  ? 2   SIA K N5  1 
HETATM 11747 O O1A . SIA K 4 .   ? 110.507 132.338 90.871  1.00 34.11  ? 2   SIA K O1A 1 
HETATM 11748 O O1B . SIA K 4 .   ? 108.341 132.198 90.221  1.00 34.11  ? 2   SIA K O1B 1 
HETATM 11749 O O4  . SIA K 4 .   ? 108.861 135.400 86.801  1.00 34.11  ? 2   SIA K O4  1 
HETATM 11750 O O6  . SIA K 4 .   ? 111.499 132.593 88.438  1.00 34.11  ? 2   SIA K O6  1 
HETATM 11751 O O7  . SIA K 4 .   ? 113.575 134.056 86.898  1.00 34.11  ? 2   SIA K O7  1 
HETATM 11752 O O8  . SIA K 4 .   ? 113.655 132.647 90.296  1.00 34.11  ? 2   SIA K O8  1 
HETATM 11753 O O9  . SIA K 4 .   ? 116.354 132.037 89.512  1.00 34.11  ? 2   SIA K O9  1 
HETATM 11754 O O10 . SIA K 4 .   ? 112.890 136.926 86.754  1.00 34.11  ? 2   SIA K O10 1 
HETATM 11755 C C1  . GAL L 4 .   ? 142.309 162.215 85.235  1.00 39.74  ? 1   GAL L C1  1 
HETATM 11756 C C2  . GAL L 4 .   ? 143.245 162.313 86.450  1.00 39.74  ? 1   GAL L C2  1 
HETATM 11757 C C3  . GAL L 4 .   ? 143.768 160.929 86.821  1.00 39.74  ? 1   GAL L C3  1 
HETATM 11758 C C4  . GAL L 4 .   ? 142.586 159.987 87.091  1.00 39.74  ? 1   GAL L C4  1 
HETATM 11759 C C5  . GAL L 4 .   ? 141.646 159.998 85.884  1.00 39.74  ? 1   GAL L C5  1 
HETATM 11760 C C6  . GAL L 4 .   ? 140.352 159.223 86.094  1.00 39.74  ? 1   GAL L C6  1 
HETATM 11761 O O1  . GAL L 4 .   ? 141.772 163.462 84.907  1.00 39.74  ? 1   GAL L O1  1 
HETATM 11762 O O2  . GAL L 4 .   ? 144.368 163.137 86.186  1.00 39.74  ? 1   GAL L O2  1 
HETATM 11763 O O3  . GAL L 4 .   ? 144.580 160.961 87.994  1.00 39.74  ? 1   GAL L O3  1 
HETATM 11764 O O4  . GAL L 4 .   ? 141.885 160.387 88.257  1.00 39.74  ? 1   GAL L O4  1 
HETATM 11765 O O5  . GAL L 4 .   ? 141.239 161.333 85.533  1.00 39.74  ? 1   GAL L O5  1 
HETATM 11766 O O6  . GAL L 4 .   ? 139.679 159.011 84.869  1.00 39.74  ? 1   GAL L O6  1 
HETATM 11767 C C1  . SIA L 4 .   ? 145.975 160.748 90.024  1.00 33.88  ? 2   SIA L C1  1 
HETATM 11768 C C2  . SIA L 4 .   ? 145.688 160.338 88.517  1.00 33.88  ? 2   SIA L C2  1 
HETATM 11769 C C3  . SIA L 4 .   ? 146.844 160.589 87.544  1.00 33.88  ? 2   SIA L C3  1 
HETATM 11770 C C4  . SIA L 4 .   ? 148.032 159.654 87.766  1.00 33.88  ? 2   SIA L C4  1 
HETATM 11771 C C5  . SIA L 4 .   ? 147.592 158.188 87.714  1.00 33.88  ? 2   SIA L C5  1 
HETATM 11772 C C6  . SIA L 4 .   ? 146.350 157.937 88.609  1.00 33.88  ? 2   SIA L C6  1 
HETATM 11773 C C7  . SIA L 4 .   ? 145.656 156.586 88.301  1.00 33.88  ? 2   SIA L C7  1 
HETATM 11774 C C8  . SIA L 4 .   ? 144.281 156.484 89.001  1.00 33.88  ? 2   SIA L C8  1 
HETATM 11775 C C9  . SIA L 4 .   ? 143.739 155.060 88.961  1.00 33.88  ? 2   SIA L C9  1 
HETATM 11776 C C10 . SIA L 4 .   ? 148.990 156.102 87.702  1.00 33.88  ? 2   SIA L C10 1 
HETATM 11777 C C11 . SIA L 4 .   ? 150.167 155.423 88.398  1.00 33.88  ? 2   SIA L C11 1 
HETATM 11778 N N5  . SIA L 4 .   ? 148.670 157.327 88.190  1.00 33.88  ? 2   SIA L N5  1 
HETATM 11779 O O1A . SIA L 4 .   ? 145.534 159.915 90.862  1.00 33.88  ? 2   SIA L O1A 1 
HETATM 11780 O O1B . SIA L 4 .   ? 146.591 161.816 90.228  1.00 33.88  ? 2   SIA L O1B 1 
HETATM 11781 O O4  . SIA L 4 .   ? 149.058 159.839 86.775  1.00 33.88  ? 2   SIA L O4  1 
HETATM 11782 O O6  . SIA L 4 .   ? 145.331 158.914 88.428  1.00 33.88  ? 2   SIA L O6  1 
HETATM 11783 O O7  . SIA L 4 .   ? 145.562 156.397 86.895  1.00 33.88  ? 2   SIA L O7  1 
HETATM 11784 O O8  . SIA L 4 .   ? 144.389 156.970 90.337  1.00 33.88  ? 2   SIA L O8  1 
HETATM 11785 O O9  . SIA L 4 .   ? 142.414 155.030 89.489  1.00 33.88  ? 2   SIA L O9  1 
HETATM 11786 O O10 . SIA L 4 .   ? 148.404 155.554 86.773  1.00 33.88  ? 2   SIA L O10 1 
HETATM 11787 C C1  . NAG M 5 .   ? 149.014 116.356 160.531 1.00 56.76  ? 601 NAG A C1  1 
HETATM 11788 C C2  . NAG M 5 .   ? 149.361 115.009 161.165 1.00 56.76  ? 601 NAG A C2  1 
HETATM 11789 C C3  . NAG M 5 .   ? 149.157 113.884 160.154 1.00 56.76  ? 601 NAG A C3  1 
HETATM 11790 C C4  . NAG M 5 .   ? 147.745 113.931 159.586 1.00 56.76  ? 601 NAG A C4  1 
HETATM 11791 C C5  . NAG M 5 .   ? 147.453 115.315 159.014 1.00 56.76  ? 601 NAG A C5  1 
HETATM 11792 C C6  . NAG M 5 .   ? 146.022 115.472 158.553 1.00 56.76  ? 601 NAG A C6  1 
HETATM 11793 C C7  . NAG M 5 .   ? 151.035 114.714 162.935 1.00 56.76  ? 601 NAG A C7  1 
HETATM 11794 C C8  . NAG M 5 .   ? 152.493 114.752 163.280 1.00 56.76  ? 601 NAG A C8  1 
HETATM 11795 N N2  . NAG M 5 .   ? 150.725 115.003 161.667 1.00 56.76  ? 601 NAG A N2  1 
HETATM 11796 O O3  . NAG M 5 .   ? 149.389 112.630 160.784 1.00 56.76  ? 601 NAG A O3  1 
HETATM 11797 O O4  . NAG M 5 .   ? 147.601 112.964 158.553 1.00 56.76  ? 601 NAG A O4  1 
HETATM 11798 O O5  . NAG M 5 .   ? 147.674 116.317 160.018 1.00 56.76  ? 601 NAG A O5  1 
HETATM 11799 O O6  . NAG M 5 .   ? 145.853 116.644 157.768 1.00 56.76  ? 601 NAG A O6  1 
HETATM 11800 O O7  . NAG M 5 .   ? 150.177 114.433 163.766 1.00 56.76  ? 601 NAG A O7  1 
HETATM 11801 C C1  . NAG N 5 .   ? 146.508 157.142 160.527 1.00 56.44  ? 601 NAG B C1  1 
HETATM 11802 C C2  . NAG N 5 .   ? 147.528 158.052 161.211 1.00 56.44  ? 601 NAG B C2  1 
HETATM 11803 C C3  . NAG N 5 .   ? 148.605 158.476 160.216 1.00 56.44  ? 601 NAG B C3  1 
HETATM 11804 C C4  . NAG N 5 .   ? 149.237 157.253 159.565 1.00 56.44  ? 601 NAG B C4  1 
HETATM 11805 C C5  . NAG N 5 .   ? 148.158 156.376 158.940 1.00 56.44  ? 601 NAG B C5  1 
HETATM 11806 C C6  . NAG N 5 .   ? 148.701 155.082 158.382 1.00 56.44  ? 601 NAG B C6  1 
HETATM 11807 C C7  . NAG N 5 .   ? 147.051 159.586 163.067 1.00 56.44  ? 601 NAG B C7  1 
HETATM 11808 C C8  . NAG N 5 .   ? 146.311 160.816 163.498 1.00 56.44  ? 601 NAG B C8  1 
HETATM 11809 N N2  . NAG N 5 .   ? 146.883 159.218 161.792 1.00 56.44  ? 601 NAG B N2  1 
HETATM 11810 O O3  . NAG N 5 .   ? 149.599 159.243 160.887 1.00 56.44  ? 601 NAG B O3  1 
HETATM 11811 O O4  . NAG N 5 .   ? 150.152 157.654 158.552 1.00 56.44  ? 601 NAG B O4  1 
HETATM 11812 O O5  . NAG N 5 .   ? 147.182 156.022 159.931 1.00 56.44  ? 601 NAG B O5  1 
HETATM 11813 O O6  . NAG N 5 .   ? 147.657 154.173 158.061 1.00 56.44  ? 601 NAG B O6  1 
HETATM 11814 O O7  . NAG N 5 .   ? 147.769 158.956 163.836 1.00 56.44  ? 601 NAG B O7  1 
HETATM 11815 C C1  . NAG O 5 .   ? 112.534 134.554 160.518 1.00 56.78  ? 601 NAG C C1  1 
HETATM 11816 C C2  . NAG O 5 .   ? 111.207 134.978 161.141 1.00 56.78  ? 601 NAG C C2  1 
HETATM 11817 C C3  . NAG O 5 .   ? 110.364 135.732 160.117 1.00 56.78  ? 601 NAG C C3  1 
HETATM 11818 C C4  . NAG O 5 .   ? 111.151 136.903 159.543 1.00 56.78  ? 601 NAG C C4  1 
HETATM 11819 C C5  . NAG O 5 .   ? 112.487 136.422 158.986 1.00 56.78  ? 601 NAG C C5  1 
HETATM 11820 C C6  . NAG O 5 .   ? 113.379 137.557 158.539 1.00 56.78  ? 601 NAG C C6  1 
HETATM 11821 C C7  . NAG O 5 .   ? 110.072 133.735 162.927 1.00 56.78  ? 601 NAG C C7  1 
HETATM 11822 C C8  . NAG O 5 .   ? 109.332 132.483 163.287 1.00 56.78  ? 601 NAG C C8  1 
HETATM 11823 N N2  . NAG O 5 .   ? 110.479 133.830 161.657 1.00 56.78  ? 601 NAG C N2  1 
HETATM 11824 O O3  . NAG O 5 .   ? 109.169 136.198 160.734 1.00 56.78  ? 601 NAG C O3  1 
HETATM 11825 O O4  . NAG O 5 .   ? 110.410 137.525 158.500 1.00 56.78  ? 601 NAG C O4  1 
HETATM 11826 O O5  . NAG O 5 .   ? 113.212 135.706 159.997 1.00 56.78  ? 601 NAG C O5  1 
HETATM 11827 O O6  . NAG O 5 .   ? 114.197 137.179 157.441 1.00 56.78  ? 601 NAG C O6  1 
HETATM 11828 O O7  . NAG O 5 .   ? 110.292 134.619 163.748 1.00 56.78  ? 601 NAG C O7  1 
# 
