data_8ZVD
# 
_entry.id   8ZVD 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZVD         pdb_00008zvd 10.2210/pdb8zvd/pdb 
WWPDB D_1300048605 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-09 ? 
2 'Structure model' 1 1 2025-04-16 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
5 2 'Structure model' '_citation.title'                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZVD 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              qiang_chen@scu.edu.cn 
_pdbx_contact_author.name_first         chen 
_pdbx_contact_author.name_last          Qiang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2398-4482 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yu, Y.'   1 ? 
'Chen, Q.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                3141 
_citation.page_last                 3141 
_citation.title                     'A toxin-antitoxin system provides phage defense via DNA damage and repair.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-58540-9 
_citation.pdbx_database_id_PubMed   40169592 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Pu, H.'   1 ? 
primary 'Chen, Y.' 2 ? 
primary 'Zhao, X.' 3 ? 
primary 'Dai, L.'  4 ? 
primary 'Tong, A.' 5 ? 
primary 'Tang, D.' 6 ? 
primary 'Chen, Q.' 7 ? 
primary 'Yu, Y.'   8 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man ShosT           49096.617 1   ? ? ? ? 
2 non-polymer syn 'PHOSPHATE ION' 94.971    2   ? ? ? ? 
3 water       nat water           18.015    339 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GASGSMNNMYLKAVIFSIADVVLPLTSNTQPQELKSRIDSELRKLFAFLSSKGIKVIFLTNKNRNVRTHDGIVTLDEYLK
RKFPESIHFCRELDNNIPAKQTGKAIDFIMAALELKRNEMIYVGRSQEDLQAATNGNTLFINATWYEPVTEYGFQFSEPK
EIARFIDVFCLREQLWGWQGHFNEDVHYYALAPFSTYVPEFTMYSANARDLAKLSVGSPDFWIRYLGASIYFSGLSEGAS
FITTYVGHNAEDPYKLANIMEHDLKGLAVSFKGKYLKDLFLRHTTAIKSQQARIAKQEVNITSQINTVNLNPAPIKNLIT
GERYTNPPKLKGKKILVIDDFCTEGNAHETARMYLKAAGANVINISWLKTINRDVSICEPTRKIRPWEANTLDVDDINYV
GTIGYAENVTHGSAPQVLSEKIQQYDNWDWPQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GASGSMNNMYLKAVIFSIADVVLPLTSNTQPQELKSRIDSELRKLFAFLSSKGIKVIFLTNKNRNVRTHDGIVTLDEYLK
RKFPESIHFCRELDNNIPAKQTGKAIDFIMAALELKRNEMIYVGRSQEDLQAATNGNTLFINATWYEPVTEYGFQFSEPK
EIARFIDVFCLREQLWGWQGHFNEDVHYYALAPFSTYVPEFTMYSANARDLAKLSVGSPDFWIRYLGASIYFSGLSEGAS
FITTYVGHNAEDPYKLANIMEHDLKGLAVSFKGKYLKDLFLRHTTAIKSQQARIAKQEVNITSQINTVNLNPAPIKNLIT
GERYTNPPKLKGKKILVIDDFCTEGNAHETARMYLKAAGANVINISWLKTINRDVSICEPTRKIRPWEANTLDVDDINYV
GTIGYAENVTHGSAPQVLSEKIQQYDNWDWPQ
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PHOSPHATE ION' PO4 
3 water           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   ALA n 
1 3   SER n 
1 4   GLY n 
1 5   SER n 
1 6   MET n 
1 7   ASN n 
1 8   ASN n 
1 9   MET n 
1 10  TYR n 
1 11  LEU n 
1 12  LYS n 
1 13  ALA n 
1 14  VAL n 
1 15  ILE n 
1 16  PHE n 
1 17  SER n 
1 18  ILE n 
1 19  ALA n 
1 20  ASP n 
1 21  VAL n 
1 22  VAL n 
1 23  LEU n 
1 24  PRO n 
1 25  LEU n 
1 26  THR n 
1 27  SER n 
1 28  ASN n 
1 29  THR n 
1 30  GLN n 
1 31  PRO n 
1 32  GLN n 
1 33  GLU n 
1 34  LEU n 
1 35  LYS n 
1 36  SER n 
1 37  ARG n 
1 38  ILE n 
1 39  ASP n 
1 40  SER n 
1 41  GLU n 
1 42  LEU n 
1 43  ARG n 
1 44  LYS n 
1 45  LEU n 
1 46  PHE n 
1 47  ALA n 
1 48  PHE n 
1 49  LEU n 
1 50  SER n 
1 51  SER n 
1 52  LYS n 
1 53  GLY n 
1 54  ILE n 
1 55  LYS n 
1 56  VAL n 
1 57  ILE n 
1 58  PHE n 
1 59  LEU n 
1 60  THR n 
1 61  ASN n 
1 62  LYS n 
1 63  ASN n 
1 64  ARG n 
1 65  ASN n 
1 66  VAL n 
1 67  ARG n 
1 68  THR n 
1 69  HIS n 
1 70  ASP n 
1 71  GLY n 
1 72  ILE n 
1 73  VAL n 
1 74  THR n 
1 75  LEU n 
1 76  ASP n 
1 77  GLU n 
1 78  TYR n 
1 79  LEU n 
1 80  LYS n 
1 81  ARG n 
1 82  LYS n 
1 83  PHE n 
1 84  PRO n 
1 85  GLU n 
1 86  SER n 
1 87  ILE n 
1 88  HIS n 
1 89  PHE n 
1 90  CYS n 
1 91  ARG n 
1 92  GLU n 
1 93  LEU n 
1 94  ASP n 
1 95  ASN n 
1 96  ASN n 
1 97  ILE n 
1 98  PRO n 
1 99  ALA n 
1 100 LYS n 
1 101 GLN n 
1 102 THR n 
1 103 GLY n 
1 104 LYS n 
1 105 ALA n 
1 106 ILE n 
1 107 ASP n 
1 108 PHE n 
1 109 ILE n 
1 110 MET n 
1 111 ALA n 
1 112 ALA n 
1 113 LEU n 
1 114 GLU n 
1 115 LEU n 
1 116 LYS n 
1 117 ARG n 
1 118 ASN n 
1 119 GLU n 
1 120 MET n 
1 121 ILE n 
1 122 TYR n 
1 123 VAL n 
1 124 GLY n 
1 125 ARG n 
1 126 SER n 
1 127 GLN n 
1 128 GLU n 
1 129 ASP n 
1 130 LEU n 
1 131 GLN n 
1 132 ALA n 
1 133 ALA n 
1 134 THR n 
1 135 ASN n 
1 136 GLY n 
1 137 ASN n 
1 138 THR n 
1 139 LEU n 
1 140 PHE n 
1 141 ILE n 
1 142 ASN n 
1 143 ALA n 
1 144 THR n 
1 145 TRP n 
1 146 TYR n 
1 147 GLU n 
1 148 PRO n 
1 149 VAL n 
1 150 THR n 
1 151 GLU n 
1 152 TYR n 
1 153 GLY n 
1 154 PHE n 
1 155 GLN n 
1 156 PHE n 
1 157 SER n 
1 158 GLU n 
1 159 PRO n 
1 160 LYS n 
1 161 GLU n 
1 162 ILE n 
1 163 ALA n 
1 164 ARG n 
1 165 PHE n 
1 166 ILE n 
1 167 ASP n 
1 168 VAL n 
1 169 PHE n 
1 170 CYS n 
1 171 LEU n 
1 172 ARG n 
1 173 GLU n 
1 174 GLN n 
1 175 LEU n 
1 176 TRP n 
1 177 GLY n 
1 178 TRP n 
1 179 GLN n 
1 180 GLY n 
1 181 HIS n 
1 182 PHE n 
1 183 ASN n 
1 184 GLU n 
1 185 ASP n 
1 186 VAL n 
1 187 HIS n 
1 188 TYR n 
1 189 TYR n 
1 190 ALA n 
1 191 LEU n 
1 192 ALA n 
1 193 PRO n 
1 194 PHE n 
1 195 SER n 
1 196 THR n 
1 197 TYR n 
1 198 VAL n 
1 199 PRO n 
1 200 GLU n 
1 201 PHE n 
1 202 THR n 
1 203 MET n 
1 204 TYR n 
1 205 SER n 
1 206 ALA n 
1 207 ASN n 
1 208 ALA n 
1 209 ARG n 
1 210 ASP n 
1 211 LEU n 
1 212 ALA n 
1 213 LYS n 
1 214 LEU n 
1 215 SER n 
1 216 VAL n 
1 217 GLY n 
1 218 SER n 
1 219 PRO n 
1 220 ASP n 
1 221 PHE n 
1 222 TRP n 
1 223 ILE n 
1 224 ARG n 
1 225 TYR n 
1 226 LEU n 
1 227 GLY n 
1 228 ALA n 
1 229 SER n 
1 230 ILE n 
1 231 TYR n 
1 232 PHE n 
1 233 SER n 
1 234 GLY n 
1 235 LEU n 
1 236 SER n 
1 237 GLU n 
1 238 GLY n 
1 239 ALA n 
1 240 SER n 
1 241 PHE n 
1 242 ILE n 
1 243 THR n 
1 244 THR n 
1 245 TYR n 
1 246 VAL n 
1 247 GLY n 
1 248 HIS n 
1 249 ASN n 
1 250 ALA n 
1 251 GLU n 
1 252 ASP n 
1 253 PRO n 
1 254 TYR n 
1 255 LYS n 
1 256 LEU n 
1 257 ALA n 
1 258 ASN n 
1 259 ILE n 
1 260 MET n 
1 261 GLU n 
1 262 HIS n 
1 263 ASP n 
1 264 LEU n 
1 265 LYS n 
1 266 GLY n 
1 267 LEU n 
1 268 ALA n 
1 269 VAL n 
1 270 SER n 
1 271 PHE n 
1 272 LYS n 
1 273 GLY n 
1 274 LYS n 
1 275 TYR n 
1 276 LEU n 
1 277 LYS n 
1 278 ASP n 
1 279 LEU n 
1 280 PHE n 
1 281 LEU n 
1 282 ARG n 
1 283 HIS n 
1 284 THR n 
1 285 THR n 
1 286 ALA n 
1 287 ILE n 
1 288 LYS n 
1 289 SER n 
1 290 GLN n 
1 291 GLN n 
1 292 ALA n 
1 293 ARG n 
1 294 ILE n 
1 295 ALA n 
1 296 LYS n 
1 297 GLN n 
1 298 GLU n 
1 299 VAL n 
1 300 ASN n 
1 301 ILE n 
1 302 THR n 
1 303 SER n 
1 304 GLN n 
1 305 ILE n 
1 306 ASN n 
1 307 THR n 
1 308 VAL n 
1 309 ASN n 
1 310 LEU n 
1 311 ASN n 
1 312 PRO n 
1 313 ALA n 
1 314 PRO n 
1 315 ILE n 
1 316 LYS n 
1 317 ASN n 
1 318 LEU n 
1 319 ILE n 
1 320 THR n 
1 321 GLY n 
1 322 GLU n 
1 323 ARG n 
1 324 TYR n 
1 325 THR n 
1 326 ASN n 
1 327 PRO n 
1 328 PRO n 
1 329 LYS n 
1 330 LEU n 
1 331 LYS n 
1 332 GLY n 
1 333 LYS n 
1 334 LYS n 
1 335 ILE n 
1 336 LEU n 
1 337 VAL n 
1 338 ILE n 
1 339 ASP n 
1 340 ASP n 
1 341 PHE n 
1 342 CYS n 
1 343 THR n 
1 344 GLU n 
1 345 GLY n 
1 346 ASN n 
1 347 ALA n 
1 348 HIS n 
1 349 GLU n 
1 350 THR n 
1 351 ALA n 
1 352 ARG n 
1 353 MET n 
1 354 TYR n 
1 355 LEU n 
1 356 LYS n 
1 357 ALA n 
1 358 ALA n 
1 359 GLY n 
1 360 ALA n 
1 361 ASN n 
1 362 VAL n 
1 363 ILE n 
1 364 ASN n 
1 365 ILE n 
1 366 SER n 
1 367 TRP n 
1 368 LEU n 
1 369 LYS n 
1 370 THR n 
1 371 ILE n 
1 372 ASN n 
1 373 ARG n 
1 374 ASP n 
1 375 VAL n 
1 376 SER n 
1 377 ILE n 
1 378 CYS n 
1 379 GLU n 
1 380 PRO n 
1 381 THR n 
1 382 ARG n 
1 383 LYS n 
1 384 ILE n 
1 385 ARG n 
1 386 PRO n 
1 387 TRP n 
1 388 GLU n 
1 389 ALA n 
1 390 ASN n 
1 391 THR n 
1 392 LEU n 
1 393 ASP n 
1 394 VAL n 
1 395 ASP n 
1 396 ASP n 
1 397 ILE n 
1 398 ASN n 
1 399 TYR n 
1 400 VAL n 
1 401 GLY n 
1 402 THR n 
1 403 ILE n 
1 404 GLY n 
1 405 TYR n 
1 406 ALA n 
1 407 GLU n 
1 408 ASN n 
1 409 VAL n 
1 410 THR n 
1 411 HIS n 
1 412 GLY n 
1 413 SER n 
1 414 ALA n 
1 415 PRO n 
1 416 GLN n 
1 417 VAL n 
1 418 LEU n 
1 419 SER n 
1 420 GLU n 
1 421 LYS n 
1 422 ILE n 
1 423 GLN n 
1 424 GLN n 
1 425 TYR n 
1 426 ASP n 
1 427 ASN n 
1 428 TRP n 
1 429 ASP n 
1 430 TRP n 
1 431 PRO n 
1 432 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   432 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 APECO1_1183 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli O1:K1 / APEC' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     405955 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PO4 non-polymer         . 'PHOSPHATE ION' ? 'O4 P -3'        94.971  
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -7  ?   ?   ?   A . n 
A 1 2   ALA 2   -6  ?   ?   ?   A . n 
A 1 3   SER 3   -5  ?   ?   ?   A . n 
A 1 4   GLY 4   -4  ?   ?   ?   A . n 
A 1 5   SER 5   -3  ?   ?   ?   A . n 
A 1 6   MET 6   -2  ?   ?   ?   A . n 
A 1 7   ASN 7   -1  ?   ?   ?   A . n 
A 1 8   ASN 8   0   ?   ?   ?   A . n 
A 1 9   MET 9   1   1   MET MET A . n 
A 1 10  TYR 10  2   2   TYR TYR A . n 
A 1 11  LEU 11  3   3   LEU LEU A . n 
A 1 12  LYS 12  4   4   LYS LYS A . n 
A 1 13  ALA 13  5   5   ALA ALA A . n 
A 1 14  VAL 14  6   6   VAL VAL A . n 
A 1 15  ILE 15  7   7   ILE ILE A . n 
A 1 16  PHE 16  8   8   PHE PHE A . n 
A 1 17  SER 17  9   9   SER SER A . n 
A 1 18  ILE 18  10  10  ILE ILE A . n 
A 1 19  ALA 19  11  11  ALA ALA A . n 
A 1 20  ASP 20  12  12  ASP ASP A . n 
A 1 21  VAL 21  13  13  VAL VAL A . n 
A 1 22  VAL 22  14  14  VAL VAL A . n 
A 1 23  LEU 23  15  15  LEU LEU A . n 
A 1 24  PRO 24  16  16  PRO PRO A . n 
A 1 25  LEU 25  17  17  LEU LEU A . n 
A 1 26  THR 26  18  18  THR THR A . n 
A 1 27  SER 27  19  19  SER SER A . n 
A 1 28  ASN 28  20  20  ASN ASN A . n 
A 1 29  THR 29  21  21  THR THR A . n 
A 1 30  GLN 30  22  22  GLN GLN A . n 
A 1 31  PRO 31  23  23  PRO PRO A . n 
A 1 32  GLN 32  24  24  GLN GLN A . n 
A 1 33  GLU 33  25  25  GLU GLU A . n 
A 1 34  LEU 34  26  26  LEU LEU A . n 
A 1 35  LYS 35  27  27  LYS LYS A . n 
A 1 36  SER 36  28  28  SER SER A . n 
A 1 37  ARG 37  29  29  ARG ARG A . n 
A 1 38  ILE 38  30  30  ILE ILE A . n 
A 1 39  ASP 39  31  31  ASP ASP A . n 
A 1 40  SER 40  32  32  SER SER A . n 
A 1 41  GLU 41  33  33  GLU GLU A . n 
A 1 42  LEU 42  34  34  LEU LEU A . n 
A 1 43  ARG 43  35  35  ARG ARG A . n 
A 1 44  LYS 44  36  36  LYS LYS A . n 
A 1 45  LEU 45  37  37  LEU LEU A . n 
A 1 46  PHE 46  38  38  PHE PHE A . n 
A 1 47  ALA 47  39  39  ALA ALA A . n 
A 1 48  PHE 48  40  40  PHE PHE A . n 
A 1 49  LEU 49  41  41  LEU LEU A . n 
A 1 50  SER 50  42  42  SER SER A . n 
A 1 51  SER 51  43  43  SER SER A . n 
A 1 52  LYS 52  44  44  LYS LYS A . n 
A 1 53  GLY 53  45  45  GLY GLY A . n 
A 1 54  ILE 54  46  46  ILE ILE A . n 
A 1 55  LYS 55  47  47  LYS LYS A . n 
A 1 56  VAL 56  48  48  VAL VAL A . n 
A 1 57  ILE 57  49  49  ILE ILE A . n 
A 1 58  PHE 58  50  50  PHE PHE A . n 
A 1 59  LEU 59  51  51  LEU LEU A . n 
A 1 60  THR 60  52  52  THR THR A . n 
A 1 61  ASN 61  53  53  ASN ASN A . n 
A 1 62  LYS 62  54  54  LYS LYS A . n 
A 1 63  ASN 63  55  55  ASN ASN A . n 
A 1 64  ARG 64  56  56  ARG ARG A . n 
A 1 65  ASN 65  57  57  ASN ASN A . n 
A 1 66  VAL 66  58  58  VAL VAL A . n 
A 1 67  ARG 67  59  59  ARG ARG A . n 
A 1 68  THR 68  60  60  THR THR A . n 
A 1 69  HIS 69  61  61  HIS HIS A . n 
A 1 70  ASP 70  62  62  ASP ASP A . n 
A 1 71  GLY 71  63  63  GLY GLY A . n 
A 1 72  ILE 72  64  64  ILE ILE A . n 
A 1 73  VAL 73  65  65  VAL VAL A . n 
A 1 74  THR 74  66  66  THR THR A . n 
A 1 75  LEU 75  67  67  LEU LEU A . n 
A 1 76  ASP 76  68  68  ASP ASP A . n 
A 1 77  GLU 77  69  69  GLU GLU A . n 
A 1 78  TYR 78  70  70  TYR TYR A . n 
A 1 79  LEU 79  71  71  LEU LEU A . n 
A 1 80  LYS 80  72  72  LYS LYS A . n 
A 1 81  ARG 81  73  73  ARG ARG A . n 
A 1 82  LYS 82  74  74  LYS LYS A . n 
A 1 83  PHE 83  75  75  PHE PHE A . n 
A 1 84  PRO 84  76  76  PRO PRO A . n 
A 1 85  GLU 85  77  77  GLU GLU A . n 
A 1 86  SER 86  78  78  SER SER A . n 
A 1 87  ILE 87  79  79  ILE ILE A . n 
A 1 88  HIS 88  80  80  HIS HIS A . n 
A 1 89  PHE 89  81  81  PHE PHE A . n 
A 1 90  CYS 90  82  82  CYS CYS A . n 
A 1 91  ARG 91  83  83  ARG ARG A . n 
A 1 92  GLU 92  84  84  GLU GLU A . n 
A 1 93  LEU 93  85  85  LEU LEU A . n 
A 1 94  ASP 94  86  86  ASP ASP A . n 
A 1 95  ASN 95  87  87  ASN ASN A . n 
A 1 96  ASN 96  88  88  ASN ASN A . n 
A 1 97  ILE 97  89  89  ILE ILE A . n 
A 1 98  PRO 98  90  90  PRO PRO A . n 
A 1 99  ALA 99  91  91  ALA ALA A . n 
A 1 100 LYS 100 92  92  LYS LYS A . n 
A 1 101 GLN 101 93  93  GLN GLN A . n 
A 1 102 THR 102 94  94  THR THR A . n 
A 1 103 GLY 103 95  95  GLY GLY A . n 
A 1 104 LYS 104 96  96  LYS LYS A . n 
A 1 105 ALA 105 97  97  ALA ALA A . n 
A 1 106 ILE 106 98  98  ILE ILE A . n 
A 1 107 ASP 107 99  99  ASP ASP A . n 
A 1 108 PHE 108 100 100 PHE PHE A . n 
A 1 109 ILE 109 101 101 ILE ILE A . n 
A 1 110 MET 110 102 102 MET MET A . n 
A 1 111 ALA 111 103 103 ALA ALA A . n 
A 1 112 ALA 112 104 104 ALA ALA A . n 
A 1 113 LEU 113 105 105 LEU LEU A . n 
A 1 114 GLU 114 106 106 GLU GLU A . n 
A 1 115 LEU 115 107 107 LEU LEU A . n 
A 1 116 LYS 116 108 108 LYS LYS A . n 
A 1 117 ARG 117 109 109 ARG ARG A . n 
A 1 118 ASN 118 110 110 ASN ASN A . n 
A 1 119 GLU 119 111 111 GLU GLU A . n 
A 1 120 MET 120 112 112 MET MET A . n 
A 1 121 ILE 121 113 113 ILE ILE A . n 
A 1 122 TYR 122 114 114 TYR TYR A . n 
A 1 123 VAL 123 115 115 VAL VAL A . n 
A 1 124 GLY 124 116 116 GLY GLY A . n 
A 1 125 ARG 125 117 117 ARG ARG A . n 
A 1 126 SER 126 118 118 SER SER A . n 
A 1 127 GLN 127 119 119 GLN GLN A . n 
A 1 128 GLU 128 120 120 GLU GLU A . n 
A 1 129 ASP 129 121 121 ASP ASP A . n 
A 1 130 LEU 130 122 122 LEU LEU A . n 
A 1 131 GLN 131 123 123 GLN GLN A . n 
A 1 132 ALA 132 124 124 ALA ALA A . n 
A 1 133 ALA 133 125 125 ALA ALA A . n 
A 1 134 THR 134 126 126 THR THR A . n 
A 1 135 ASN 135 127 127 ASN ASN A . n 
A 1 136 GLY 136 128 128 GLY GLY A . n 
A 1 137 ASN 137 129 129 ASN ASN A . n 
A 1 138 THR 138 130 130 THR THR A . n 
A 1 139 LEU 139 131 131 LEU LEU A . n 
A 1 140 PHE 140 132 132 PHE PHE A . n 
A 1 141 ILE 141 133 133 ILE ILE A . n 
A 1 142 ASN 142 134 134 ASN ASN A . n 
A 1 143 ALA 143 135 135 ALA ALA A . n 
A 1 144 THR 144 136 136 THR THR A . n 
A 1 145 TRP 145 137 137 TRP TRP A . n 
A 1 146 TYR 146 138 138 TYR TYR A . n 
A 1 147 GLU 147 139 139 GLU GLU A . n 
A 1 148 PRO 148 140 140 PRO PRO A . n 
A 1 149 VAL 149 141 141 VAL VAL A . n 
A 1 150 THR 150 142 142 THR THR A . n 
A 1 151 GLU 151 143 143 GLU GLU A . n 
A 1 152 TYR 152 144 144 TYR TYR A . n 
A 1 153 GLY 153 145 145 GLY GLY A . n 
A 1 154 PHE 154 146 146 PHE PHE A . n 
A 1 155 GLN 155 147 147 GLN GLN A . n 
A 1 156 PHE 156 148 148 PHE PHE A . n 
A 1 157 SER 157 149 149 SER SER A . n 
A 1 158 GLU 158 150 150 GLU GLU A . n 
A 1 159 PRO 159 151 151 PRO PRO A . n 
A 1 160 LYS 160 152 152 LYS LYS A . n 
A 1 161 GLU 161 153 153 GLU GLU A . n 
A 1 162 ILE 162 154 154 ILE ILE A . n 
A 1 163 ALA 163 155 155 ALA ALA A . n 
A 1 164 ARG 164 156 156 ARG ARG A . n 
A 1 165 PHE 165 157 157 PHE PHE A . n 
A 1 166 ILE 166 158 158 ILE ILE A . n 
A 1 167 ASP 167 159 159 ASP ASP A . n 
A 1 168 VAL 168 160 160 VAL VAL A . n 
A 1 169 PHE 169 161 161 PHE PHE A . n 
A 1 170 CYS 170 162 162 CYS CYS A . n 
A 1 171 LEU 171 163 163 LEU LEU A . n 
A 1 172 ARG 172 164 164 ARG ARG A . n 
A 1 173 GLU 173 165 165 GLU GLU A . n 
A 1 174 GLN 174 166 166 GLN GLN A . n 
A 1 175 LEU 175 167 167 LEU LEU A . n 
A 1 176 TRP 176 168 168 TRP TRP A . n 
A 1 177 GLY 177 169 169 GLY GLY A . n 
A 1 178 TRP 178 170 170 TRP TRP A . n 
A 1 179 GLN 179 171 171 GLN GLN A . n 
A 1 180 GLY 180 172 172 GLY GLY A . n 
A 1 181 HIS 181 173 173 HIS HIS A . n 
A 1 182 PHE 182 174 174 PHE PHE A . n 
A 1 183 ASN 183 175 175 ASN ASN A . n 
A 1 184 GLU 184 176 176 GLU GLU A . n 
A 1 185 ASP 185 177 177 ASP ASP A . n 
A 1 186 VAL 186 178 178 VAL VAL A . n 
A 1 187 HIS 187 179 179 HIS HIS A . n 
A 1 188 TYR 188 180 180 TYR TYR A . n 
A 1 189 TYR 189 181 181 TYR TYR A . n 
A 1 190 ALA 190 182 182 ALA ALA A . n 
A 1 191 LEU 191 183 183 LEU LEU A . n 
A 1 192 ALA 192 184 184 ALA ALA A . n 
A 1 193 PRO 193 185 185 PRO PRO A . n 
A 1 194 PHE 194 186 186 PHE PHE A . n 
A 1 195 SER 195 187 187 SER SER A . n 
A 1 196 THR 196 188 188 THR THR A . n 
A 1 197 TYR 197 189 189 TYR TYR A . n 
A 1 198 VAL 198 190 190 VAL VAL A . n 
A 1 199 PRO 199 191 191 PRO PRO A . n 
A 1 200 GLU 200 192 192 GLU GLU A . n 
A 1 201 PHE 201 193 193 PHE PHE A . n 
A 1 202 THR 202 194 194 THR THR A . n 
A 1 203 MET 203 195 195 MET MET A . n 
A 1 204 TYR 204 196 196 TYR TYR A . n 
A 1 205 SER 205 197 197 SER SER A . n 
A 1 206 ALA 206 198 198 ALA ALA A . n 
A 1 207 ASN 207 199 199 ASN ASN A . n 
A 1 208 ALA 208 200 ?   ?   ?   A . n 
A 1 209 ARG 209 201 ?   ?   ?   A . n 
A 1 210 ASP 210 202 ?   ?   ?   A . n 
A 1 211 LEU 211 203 ?   ?   ?   A . n 
A 1 212 ALA 212 204 204 ALA ALA A . n 
A 1 213 LYS 213 205 205 LYS LYS A . n 
A 1 214 LEU 214 206 206 LEU LEU A . n 
A 1 215 SER 215 207 207 SER SER A . n 
A 1 216 VAL 216 208 208 VAL VAL A . n 
A 1 217 GLY 217 209 209 GLY GLY A . n 
A 1 218 SER 218 210 210 SER SER A . n 
A 1 219 PRO 219 211 211 PRO PRO A . n 
A 1 220 ASP 220 212 212 ASP ASP A . n 
A 1 221 PHE 221 213 213 PHE PHE A . n 
A 1 222 TRP 222 214 214 TRP TRP A . n 
A 1 223 ILE 223 215 215 ILE ILE A . n 
A 1 224 ARG 224 216 216 ARG ARG A . n 
A 1 225 TYR 225 217 217 TYR TYR A . n 
A 1 226 LEU 226 218 218 LEU LEU A . n 
A 1 227 GLY 227 219 219 GLY GLY A . n 
A 1 228 ALA 228 220 220 ALA ALA A . n 
A 1 229 SER 229 221 221 SER SER A . n 
A 1 230 ILE 230 222 222 ILE ILE A . n 
A 1 231 TYR 231 223 223 TYR TYR A . n 
A 1 232 PHE 232 224 224 PHE PHE A . n 
A 1 233 SER 233 225 225 SER SER A . n 
A 1 234 GLY 234 226 226 GLY GLY A . n 
A 1 235 LEU 235 227 227 LEU LEU A . n 
A 1 236 SER 236 228 228 SER SER A . n 
A 1 237 GLU 237 229 229 GLU GLU A . n 
A 1 238 GLY 238 230 230 GLY GLY A . n 
A 1 239 ALA 239 231 231 ALA ALA A . n 
A 1 240 SER 240 232 232 SER SER A . n 
A 1 241 PHE 241 233 233 PHE PHE A . n 
A 1 242 ILE 242 234 234 ILE ILE A . n 
A 1 243 THR 243 235 235 THR THR A . n 
A 1 244 THR 244 236 236 THR THR A . n 
A 1 245 TYR 245 237 237 TYR TYR A . n 
A 1 246 VAL 246 238 238 VAL VAL A . n 
A 1 247 GLY 247 239 239 GLY GLY A . n 
A 1 248 HIS 248 240 240 HIS HIS A . n 
A 1 249 ASN 249 241 241 ASN ASN A . n 
A 1 250 ALA 250 242 242 ALA ALA A . n 
A 1 251 GLU 251 243 243 GLU GLU A . n 
A 1 252 ASP 252 244 244 ASP ASP A . n 
A 1 253 PRO 253 245 245 PRO PRO A . n 
A 1 254 TYR 254 246 246 TYR TYR A . n 
A 1 255 LYS 255 247 247 LYS LYS A . n 
A 1 256 LEU 256 248 248 LEU LEU A . n 
A 1 257 ALA 257 249 249 ALA ALA A . n 
A 1 258 ASN 258 250 250 ASN ASN A . n 
A 1 259 ILE 259 251 251 ILE ILE A . n 
A 1 260 MET 260 252 252 MET MET A . n 
A 1 261 GLU 261 253 253 GLU GLU A . n 
A 1 262 HIS 262 254 254 HIS HIS A . n 
A 1 263 ASP 263 255 255 ASP ASP A . n 
A 1 264 LEU 264 256 256 LEU LEU A . n 
A 1 265 LYS 265 257 257 LYS LYS A . n 
A 1 266 GLY 266 258 258 GLY GLY A . n 
A 1 267 LEU 267 259 259 LEU LEU A . n 
A 1 268 ALA 268 260 260 ALA ALA A . n 
A 1 269 VAL 269 261 261 VAL VAL A . n 
A 1 270 SER 270 262 262 SER SER A . n 
A 1 271 PHE 271 263 263 PHE PHE A . n 
A 1 272 LYS 272 264 264 LYS LYS A . n 
A 1 273 GLY 273 265 265 GLY GLY A . n 
A 1 274 LYS 274 266 266 LYS LYS A . n 
A 1 275 TYR 275 267 267 TYR TYR A . n 
A 1 276 LEU 276 268 268 LEU LEU A . n 
A 1 277 LYS 277 269 269 LYS LYS A . n 
A 1 278 ASP 278 270 270 ASP ASP A . n 
A 1 279 LEU 279 271 271 LEU LEU A . n 
A 1 280 PHE 280 272 272 PHE PHE A . n 
A 1 281 LEU 281 273 273 LEU LEU A . n 
A 1 282 ARG 282 274 274 ARG ARG A . n 
A 1 283 HIS 283 275 275 HIS HIS A . n 
A 1 284 THR 284 276 276 THR THR A . n 
A 1 285 THR 285 277 277 THR THR A . n 
A 1 286 ALA 286 278 278 ALA ALA A . n 
A 1 287 ILE 287 279 279 ILE ILE A . n 
A 1 288 LYS 288 280 280 LYS LYS A . n 
A 1 289 SER 289 281 281 SER SER A . n 
A 1 290 GLN 290 282 282 GLN GLN A . n 
A 1 291 GLN 291 283 ?   ?   ?   A . n 
A 1 292 ALA 292 284 ?   ?   ?   A . n 
A 1 293 ARG 293 285 ?   ?   ?   A . n 
A 1 294 ILE 294 286 ?   ?   ?   A . n 
A 1 295 ALA 295 287 ?   ?   ?   A . n 
A 1 296 LYS 296 288 ?   ?   ?   A . n 
A 1 297 GLN 297 289 ?   ?   ?   A . n 
A 1 298 GLU 298 290 ?   ?   ?   A . n 
A 1 299 VAL 299 291 291 VAL VAL A . n 
A 1 300 ASN 300 292 292 ASN ASN A . n 
A 1 301 ILE 301 293 293 ILE ILE A . n 
A 1 302 THR 302 294 294 THR THR A . n 
A 1 303 SER 303 295 295 SER SER A . n 
A 1 304 GLN 304 296 296 GLN GLN A . n 
A 1 305 ILE 305 297 297 ILE ILE A . n 
A 1 306 ASN 306 298 298 ASN ASN A . n 
A 1 307 THR 307 299 299 THR THR A . n 
A 1 308 VAL 308 300 300 VAL VAL A . n 
A 1 309 ASN 309 301 301 ASN ASN A . n 
A 1 310 LEU 310 302 302 LEU LEU A . n 
A 1 311 ASN 311 303 303 ASN ASN A . n 
A 1 312 PRO 312 304 304 PRO PRO A . n 
A 1 313 ALA 313 305 305 ALA ALA A . n 
A 1 314 PRO 314 306 306 PRO PRO A . n 
A 1 315 ILE 315 307 307 ILE ILE A . n 
A 1 316 LYS 316 308 308 LYS LYS A . n 
A 1 317 ASN 317 309 309 ASN ASN A . n 
A 1 318 LEU 318 310 310 LEU LEU A . n 
A 1 319 ILE 319 311 311 ILE ILE A . n 
A 1 320 THR 320 312 312 THR THR A . n 
A 1 321 GLY 321 313 313 GLY GLY A . n 
A 1 322 GLU 322 314 314 GLU GLU A . n 
A 1 323 ARG 323 315 315 ARG ARG A . n 
A 1 324 TYR 324 316 316 TYR TYR A . n 
A 1 325 THR 325 317 317 THR THR A . n 
A 1 326 ASN 326 318 318 ASN ASN A . n 
A 1 327 PRO 327 319 319 PRO PRO A . n 
A 1 328 PRO 328 320 320 PRO PRO A . n 
A 1 329 LYS 329 321 321 LYS LYS A . n 
A 1 330 LEU 330 322 322 LEU LEU A . n 
A 1 331 LYS 331 323 323 LYS LYS A . n 
A 1 332 GLY 332 324 324 GLY GLY A . n 
A 1 333 LYS 333 325 325 LYS LYS A . n 
A 1 334 LYS 334 326 326 LYS LYS A . n 
A 1 335 ILE 335 327 327 ILE ILE A . n 
A 1 336 LEU 336 328 328 LEU LEU A . n 
A 1 337 VAL 337 329 329 VAL VAL A . n 
A 1 338 ILE 338 330 330 ILE ILE A . n 
A 1 339 ASP 339 331 331 ASP ASP A . n 
A 1 340 ASP 340 332 332 ASP ASP A . n 
A 1 341 PHE 341 333 333 PHE PHE A . n 
A 1 342 CYS 342 334 334 CYS CYS A . n 
A 1 343 THR 343 335 335 THR THR A . n 
A 1 344 GLU 344 336 336 GLU GLU A . n 
A 1 345 GLY 345 337 337 GLY GLY A . n 
A 1 346 ASN 346 338 338 ASN ASN A . n 
A 1 347 ALA 347 339 339 ALA ALA A . n 
A 1 348 HIS 348 340 340 HIS HIS A . n 
A 1 349 GLU 349 341 341 GLU GLU A . n 
A 1 350 THR 350 342 342 THR THR A . n 
A 1 351 ALA 351 343 343 ALA ALA A . n 
A 1 352 ARG 352 344 344 ARG ARG A . n 
A 1 353 MET 353 345 345 MET MET A . n 
A 1 354 TYR 354 346 346 TYR TYR A . n 
A 1 355 LEU 355 347 347 LEU LEU A . n 
A 1 356 LYS 356 348 348 LYS LYS A . n 
A 1 357 ALA 357 349 349 ALA ALA A . n 
A 1 358 ALA 358 350 350 ALA ALA A . n 
A 1 359 GLY 359 351 351 GLY GLY A . n 
A 1 360 ALA 360 352 352 ALA ALA A . n 
A 1 361 ASN 361 353 353 ASN ASN A . n 
A 1 362 VAL 362 354 354 VAL VAL A . n 
A 1 363 ILE 363 355 355 ILE ILE A . n 
A 1 364 ASN 364 356 356 ASN ASN A . n 
A 1 365 ILE 365 357 357 ILE ILE A . n 
A 1 366 SER 366 358 358 SER SER A . n 
A 1 367 TRP 367 359 359 TRP TRP A . n 
A 1 368 LEU 368 360 360 LEU LEU A . n 
A 1 369 LYS 369 361 361 LYS LYS A . n 
A 1 370 THR 370 362 362 THR THR A . n 
A 1 371 ILE 371 363 363 ILE ILE A . n 
A 1 372 ASN 372 364 364 ASN ASN A . n 
A 1 373 ARG 373 365 365 ARG ARG A . n 
A 1 374 ASP 374 366 366 ASP ASP A . n 
A 1 375 VAL 375 367 367 VAL VAL A . n 
A 1 376 SER 376 368 368 SER SER A . n 
A 1 377 ILE 377 369 369 ILE ILE A . n 
A 1 378 CYS 378 370 370 CYS CYS A . n 
A 1 379 GLU 379 371 371 GLU GLU A . n 
A 1 380 PRO 380 372 372 PRO PRO A . n 
A 1 381 THR 381 373 373 THR THR A . n 
A 1 382 ARG 382 374 374 ARG ARG A . n 
A 1 383 LYS 383 375 375 LYS LYS A . n 
A 1 384 ILE 384 376 376 ILE ILE A . n 
A 1 385 ARG 385 377 377 ARG ARG A . n 
A 1 386 PRO 386 378 378 PRO PRO A . n 
A 1 387 TRP 387 379 379 TRP TRP A . n 
A 1 388 GLU 388 380 380 GLU GLU A . n 
A 1 389 ALA 389 381 381 ALA ALA A . n 
A 1 390 ASN 390 382 382 ASN ASN A . n 
A 1 391 THR 391 383 383 THR THR A . n 
A 1 392 LEU 392 384 384 LEU LEU A . n 
A 1 393 ASP 393 385 385 ASP ASP A . n 
A 1 394 VAL 394 386 386 VAL VAL A . n 
A 1 395 ASP 395 387 387 ASP ASP A . n 
A 1 396 ASP 396 388 388 ASP ASP A . n 
A 1 397 ILE 397 389 389 ILE ILE A . n 
A 1 398 ASN 398 390 390 ASN ASN A . n 
A 1 399 TYR 399 391 391 TYR TYR A . n 
A 1 400 VAL 400 392 392 VAL VAL A . n 
A 1 401 GLY 401 393 393 GLY GLY A . n 
A 1 402 THR 402 394 394 THR THR A . n 
A 1 403 ILE 403 395 395 ILE ILE A . n 
A 1 404 GLY 404 396 396 GLY GLY A . n 
A 1 405 TYR 405 397 397 TYR TYR A . n 
A 1 406 ALA 406 398 398 ALA ALA A . n 
A 1 407 GLU 407 399 399 GLU GLU A . n 
A 1 408 ASN 408 400 400 ASN ASN A . n 
A 1 409 VAL 409 401 401 VAL VAL A . n 
A 1 410 THR 410 402 402 THR THR A . n 
A 1 411 HIS 411 403 403 HIS HIS A . n 
A 1 412 GLY 412 404 404 GLY GLY A . n 
A 1 413 SER 413 405 405 SER SER A . n 
A 1 414 ALA 414 406 406 ALA ALA A . n 
A 1 415 PRO 415 407 407 PRO PRO A . n 
A 1 416 GLN 416 408 408 GLN GLN A . n 
A 1 417 VAL 417 409 409 VAL VAL A . n 
A 1 418 LEU 418 410 410 LEU LEU A . n 
A 1 419 SER 419 411 411 SER SER A . n 
A 1 420 GLU 420 412 412 GLU GLU A . n 
A 1 421 LYS 421 413 413 LYS LYS A . n 
A 1 422 ILE 422 414 414 ILE ILE A . n 
A 1 423 GLN 423 415 415 GLN GLN A . n 
A 1 424 GLN 424 416 416 GLN GLN A . n 
A 1 425 TYR 425 417 417 TYR TYR A . n 
A 1 426 ASP 426 418 418 ASP ASP A . n 
A 1 427 ASN 427 419 419 ASN ASN A . n 
A 1 428 TRP 428 420 420 TRP TRP A . n 
A 1 429 ASP 429 421 421 ASP ASP A . n 
A 1 430 TRP 430 422 422 TRP TRP A . n 
A 1 431 PRO 431 423 423 PRO PRO A . n 
A 1 432 GLN 432 424 424 GLN GLN A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        PO4 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   PO4 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 PO4 1   501 1   PO4 PO4 A . 
C 2 PO4 1   502 2   PO4 PO4 A . 
D 3 HOH 1   601 308 HOH HOH A . 
D 3 HOH 2   602 338 HOH HOH A . 
D 3 HOH 3   603 246 HOH HOH A . 
D 3 HOH 4   604 322 HOH HOH A . 
D 3 HOH 5   605 131 HOH HOH A . 
D 3 HOH 6   606 256 HOH HOH A . 
D 3 HOH 7   607 143 HOH HOH A . 
D 3 HOH 8   608 257 HOH HOH A . 
D 3 HOH 9   609 86  HOH HOH A . 
D 3 HOH 10  610 290 HOH HOH A . 
D 3 HOH 11  611 162 HOH HOH A . 
D 3 HOH 12  612 134 HOH HOH A . 
D 3 HOH 13  613 264 HOH HOH A . 
D 3 HOH 14  614 139 HOH HOH A . 
D 3 HOH 15  615 157 HOH HOH A . 
D 3 HOH 16  616 137 HOH HOH A . 
D 3 HOH 17  617 230 HOH HOH A . 
D 3 HOH 18  618 339 HOH HOH A . 
D 3 HOH 19  619 278 HOH HOH A . 
D 3 HOH 20  620 226 HOH HOH A . 
D 3 HOH 21  621 37  HOH HOH A . 
D 3 HOH 22  622 71  HOH HOH A . 
D 3 HOH 23  623 20  HOH HOH A . 
D 3 HOH 24  624 69  HOH HOH A . 
D 3 HOH 25  625 249 HOH HOH A . 
D 3 HOH 26  626 252 HOH HOH A . 
D 3 HOH 27  627 128 HOH HOH A . 
D 3 HOH 28  628 43  HOH HOH A . 
D 3 HOH 29  629 163 HOH HOH A . 
D 3 HOH 30  630 75  HOH HOH A . 
D 3 HOH 31  631 98  HOH HOH A . 
D 3 HOH 32  632 203 HOH HOH A . 
D 3 HOH 33  633 165 HOH HOH A . 
D 3 HOH 34  634 142 HOH HOH A . 
D 3 HOH 35  635 52  HOH HOH A . 
D 3 HOH 36  636 122 HOH HOH A . 
D 3 HOH 37  637 90  HOH HOH A . 
D 3 HOH 38  638 8   HOH HOH A . 
D 3 HOH 39  639 15  HOH HOH A . 
D 3 HOH 40  640 185 HOH HOH A . 
D 3 HOH 41  641 283 HOH HOH A . 
D 3 HOH 42  642 174 HOH HOH A . 
D 3 HOH 43  643 74  HOH HOH A . 
D 3 HOH 44  644 186 HOH HOH A . 
D 3 HOH 45  645 44  HOH HOH A . 
D 3 HOH 46  646 9   HOH HOH A . 
D 3 HOH 47  647 149 HOH HOH A . 
D 3 HOH 48  648 59  HOH HOH A . 
D 3 HOH 49  649 2   HOH HOH A . 
D 3 HOH 50  650 129 HOH HOH A . 
D 3 HOH 51  651 260 HOH HOH A . 
D 3 HOH 52  652 10  HOH HOH A . 
D 3 HOH 53  653 263 HOH HOH A . 
D 3 HOH 54  654 95  HOH HOH A . 
D 3 HOH 55  655 91  HOH HOH A . 
D 3 HOH 56  656 192 HOH HOH A . 
D 3 HOH 57  657 104 HOH HOH A . 
D 3 HOH 58  658 317 HOH HOH A . 
D 3 HOH 59  659 213 HOH HOH A . 
D 3 HOH 60  660 106 HOH HOH A . 
D 3 HOH 61  661 89  HOH HOH A . 
D 3 HOH 62  662 36  HOH HOH A . 
D 3 HOH 63  663 179 HOH HOH A . 
D 3 HOH 64  664 62  HOH HOH A . 
D 3 HOH 65  665 53  HOH HOH A . 
D 3 HOH 66  666 31  HOH HOH A . 
D 3 HOH 67  667 3   HOH HOH A . 
D 3 HOH 68  668 23  HOH HOH A . 
D 3 HOH 69  669 83  HOH HOH A . 
D 3 HOH 70  670 135 HOH HOH A . 
D 3 HOH 71  671 182 HOH HOH A . 
D 3 HOH 72  672 47  HOH HOH A . 
D 3 HOH 73  673 271 HOH HOH A . 
D 3 HOH 74  674 46  HOH HOH A . 
D 3 HOH 75  675 26  HOH HOH A . 
D 3 HOH 76  676 33  HOH HOH A . 
D 3 HOH 77  677 73  HOH HOH A . 
D 3 HOH 78  678 107 HOH HOH A . 
D 3 HOH 79  679 45  HOH HOH A . 
D 3 HOH 80  680 100 HOH HOH A . 
D 3 HOH 81  681 254 HOH HOH A . 
D 3 HOH 82  682 41  HOH HOH A . 
D 3 HOH 83  683 76  HOH HOH A . 
D 3 HOH 84  684 337 HOH HOH A . 
D 3 HOH 85  685 115 HOH HOH A . 
D 3 HOH 86  686 92  HOH HOH A . 
D 3 HOH 87  687 56  HOH HOH A . 
D 3 HOH 88  688 120 HOH HOH A . 
D 3 HOH 89  689 156 HOH HOH A . 
D 3 HOH 90  690 1   HOH HOH A . 
D 3 HOH 91  691 334 HOH HOH A . 
D 3 HOH 92  692 313 HOH HOH A . 
D 3 HOH 93  693 160 HOH HOH A . 
D 3 HOH 94  694 235 HOH HOH A . 
D 3 HOH 95  695 77  HOH HOH A . 
D 3 HOH 96  696 155 HOH HOH A . 
D 3 HOH 97  697 50  HOH HOH A . 
D 3 HOH 98  698 40  HOH HOH A . 
D 3 HOH 99  699 27  HOH HOH A . 
D 3 HOH 100 700 204 HOH HOH A . 
D 3 HOH 101 701 81  HOH HOH A . 
D 3 HOH 102 702 113 HOH HOH A . 
D 3 HOH 103 703 214 HOH HOH A . 
D 3 HOH 104 704 63  HOH HOH A . 
D 3 HOH 105 705 132 HOH HOH A . 
D 3 HOH 106 706 18  HOH HOH A . 
D 3 HOH 107 707 38  HOH HOH A . 
D 3 HOH 108 708 17  HOH HOH A . 
D 3 HOH 109 709 96  HOH HOH A . 
D 3 HOH 110 710 6   HOH HOH A . 
D 3 HOH 111 711 57  HOH HOH A . 
D 3 HOH 112 712 11  HOH HOH A . 
D 3 HOH 113 713 341 HOH HOH A . 
D 3 HOH 114 714 145 HOH HOH A . 
D 3 HOH 115 715 320 HOH HOH A . 
D 3 HOH 116 716 67  HOH HOH A . 
D 3 HOH 117 717 133 HOH HOH A . 
D 3 HOH 118 718 61  HOH HOH A . 
D 3 HOH 119 719 277 HOH HOH A . 
D 3 HOH 120 720 12  HOH HOH A . 
D 3 HOH 121 721 99  HOH HOH A . 
D 3 HOH 122 722 151 HOH HOH A . 
D 3 HOH 123 723 55  HOH HOH A . 
D 3 HOH 124 724 176 HOH HOH A . 
D 3 HOH 125 725 175 HOH HOH A . 
D 3 HOH 126 726 164 HOH HOH A . 
D 3 HOH 127 727 229 HOH HOH A . 
D 3 HOH 128 728 88  HOH HOH A . 
D 3 HOH 129 729 4   HOH HOH A . 
D 3 HOH 130 730 66  HOH HOH A . 
D 3 HOH 131 731 112 HOH HOH A . 
D 3 HOH 132 732 152 HOH HOH A . 
D 3 HOH 133 733 158 HOH HOH A . 
D 3 HOH 134 734 111 HOH HOH A . 
D 3 HOH 135 735 224 HOH HOH A . 
D 3 HOH 136 736 207 HOH HOH A . 
D 3 HOH 137 737 275 HOH HOH A . 
D 3 HOH 138 738 173 HOH HOH A . 
D 3 HOH 139 739 21  HOH HOH A . 
D 3 HOH 140 740 206 HOH HOH A . 
D 3 HOH 141 741 307 HOH HOH A . 
D 3 HOH 142 742 306 HOH HOH A . 
D 3 HOH 143 743 177 HOH HOH A . 
D 3 HOH 144 744 210 HOH HOH A . 
D 3 HOH 145 745 58  HOH HOH A . 
D 3 HOH 146 746 19  HOH HOH A . 
D 3 HOH 147 747 14  HOH HOH A . 
D 3 HOH 148 748 233 HOH HOH A . 
D 3 HOH 149 749 170 HOH HOH A . 
D 3 HOH 150 750 318 HOH HOH A . 
D 3 HOH 151 751 94  HOH HOH A . 
D 3 HOH 152 752 289 HOH HOH A . 
D 3 HOH 153 753 221 HOH HOH A . 
D 3 HOH 154 754 255 HOH HOH A . 
D 3 HOH 155 755 191 HOH HOH A . 
D 3 HOH 156 756 48  HOH HOH A . 
D 3 HOH 157 757 84  HOH HOH A . 
D 3 HOH 158 758 34  HOH HOH A . 
D 3 HOH 159 759 194 HOH HOH A . 
D 3 HOH 160 760 16  HOH HOH A . 
D 3 HOH 161 761 269 HOH HOH A . 
D 3 HOH 162 762 29  HOH HOH A . 
D 3 HOH 163 763 119 HOH HOH A . 
D 3 HOH 164 764 51  HOH HOH A . 
D 3 HOH 165 765 54  HOH HOH A . 
D 3 HOH 166 766 65  HOH HOH A . 
D 3 HOH 167 767 253 HOH HOH A . 
D 3 HOH 168 768 146 HOH HOH A . 
D 3 HOH 169 769 13  HOH HOH A . 
D 3 HOH 170 770 218 HOH HOH A . 
D 3 HOH 171 771 72  HOH HOH A . 
D 3 HOH 172 772 196 HOH HOH A . 
D 3 HOH 173 773 159 HOH HOH A . 
D 3 HOH 174 774 172 HOH HOH A . 
D 3 HOH 175 775 82  HOH HOH A . 
D 3 HOH 176 776 144 HOH HOH A . 
D 3 HOH 177 777 85  HOH HOH A . 
D 3 HOH 178 778 169 HOH HOH A . 
D 3 HOH 179 779 28  HOH HOH A . 
D 3 HOH 180 780 5   HOH HOH A . 
D 3 HOH 181 781 49  HOH HOH A . 
D 3 HOH 182 782 259 HOH HOH A . 
D 3 HOH 183 783 223 HOH HOH A . 
D 3 HOH 184 784 123 HOH HOH A . 
D 3 HOH 185 785 78  HOH HOH A . 
D 3 HOH 186 786 217 HOH HOH A . 
D 3 HOH 187 787 80  HOH HOH A . 
D 3 HOH 188 788 209 HOH HOH A . 
D 3 HOH 189 789 153 HOH HOH A . 
D 3 HOH 190 790 24  HOH HOH A . 
D 3 HOH 191 791 241 HOH HOH A . 
D 3 HOH 192 792 126 HOH HOH A . 
D 3 HOH 193 793 227 HOH HOH A . 
D 3 HOH 194 794 284 HOH HOH A . 
D 3 HOH 195 795 39  HOH HOH A . 
D 3 HOH 196 796 150 HOH HOH A . 
D 3 HOH 197 797 340 HOH HOH A . 
D 3 HOH 198 798 30  HOH HOH A . 
D 3 HOH 199 799 42  HOH HOH A . 
D 3 HOH 200 800 7   HOH HOH A . 
D 3 HOH 201 801 321 HOH HOH A . 
D 3 HOH 202 802 178 HOH HOH A . 
D 3 HOH 203 803 201 HOH HOH A . 
D 3 HOH 204 804 70  HOH HOH A . 
D 3 HOH 205 805 130 HOH HOH A . 
D 3 HOH 206 806 248 HOH HOH A . 
D 3 HOH 207 807 154 HOH HOH A . 
D 3 HOH 208 808 315 HOH HOH A . 
D 3 HOH 209 809 68  HOH HOH A . 
D 3 HOH 210 810 220 HOH HOH A . 
D 3 HOH 211 811 336 HOH HOH A . 
D 3 HOH 212 812 319 HOH HOH A . 
D 3 HOH 213 813 265 HOH HOH A . 
D 3 HOH 214 814 247 HOH HOH A . 
D 3 HOH 215 815 101 HOH HOH A . 
D 3 HOH 216 816 166 HOH HOH A . 
D 3 HOH 217 817 110 HOH HOH A . 
D 3 HOH 218 818 291 HOH HOH A . 
D 3 HOH 219 819 294 HOH HOH A . 
D 3 HOH 220 820 127 HOH HOH A . 
D 3 HOH 221 821 188 HOH HOH A . 
D 3 HOH 222 822 35  HOH HOH A . 
D 3 HOH 223 823 109 HOH HOH A . 
D 3 HOH 224 824 147 HOH HOH A . 
D 3 HOH 225 825 299 HOH HOH A . 
D 3 HOH 226 826 105 HOH HOH A . 
D 3 HOH 227 827 168 HOH HOH A . 
D 3 HOH 228 828 136 HOH HOH A . 
D 3 HOH 229 829 332 HOH HOH A . 
D 3 HOH 230 830 261 HOH HOH A . 
D 3 HOH 231 831 267 HOH HOH A . 
D 3 HOH 232 832 280 HOH HOH A . 
D 3 HOH 233 833 64  HOH HOH A . 
D 3 HOH 234 834 97  HOH HOH A . 
D 3 HOH 235 835 245 HOH HOH A . 
D 3 HOH 236 836 25  HOH HOH A . 
D 3 HOH 237 837 60  HOH HOH A . 
D 3 HOH 238 838 32  HOH HOH A . 
D 3 HOH 239 839 309 HOH HOH A . 
D 3 HOH 240 840 305 HOH HOH A . 
D 3 HOH 241 841 285 HOH HOH A . 
D 3 HOH 242 842 87  HOH HOH A . 
D 3 HOH 243 843 117 HOH HOH A . 
D 3 HOH 244 844 330 HOH HOH A . 
D 3 HOH 245 845 114 HOH HOH A . 
D 3 HOH 246 846 234 HOH HOH A . 
D 3 HOH 247 847 304 HOH HOH A . 
D 3 HOH 248 848 324 HOH HOH A . 
D 3 HOH 249 849 243 HOH HOH A . 
D 3 HOH 250 850 208 HOH HOH A . 
D 3 HOH 251 851 231 HOH HOH A . 
D 3 HOH 252 852 268 HOH HOH A . 
D 3 HOH 253 853 181 HOH HOH A . 
D 3 HOH 254 854 79  HOH HOH A . 
D 3 HOH 255 855 293 HOH HOH A . 
D 3 HOH 256 856 193 HOH HOH A . 
D 3 HOH 257 857 251 HOH HOH A . 
D 3 HOH 258 858 200 HOH HOH A . 
D 3 HOH 259 859 212 HOH HOH A . 
D 3 HOH 260 860 183 HOH HOH A . 
D 3 HOH 261 861 270 HOH HOH A . 
D 3 HOH 262 862 216 HOH HOH A . 
D 3 HOH 263 863 279 HOH HOH A . 
D 3 HOH 264 864 161 HOH HOH A . 
D 3 HOH 265 865 262 HOH HOH A . 
D 3 HOH 266 866 232 HOH HOH A . 
D 3 HOH 267 867 239 HOH HOH A . 
D 3 HOH 268 868 258 HOH HOH A . 
D 3 HOH 269 869 333 HOH HOH A . 
D 3 HOH 270 870 121 HOH HOH A . 
D 3 HOH 271 871 190 HOH HOH A . 
D 3 HOH 272 872 215 HOH HOH A . 
D 3 HOH 273 873 148 HOH HOH A . 
D 3 HOH 274 874 108 HOH HOH A . 
D 3 HOH 275 875 22  HOH HOH A . 
D 3 HOH 276 876 244 HOH HOH A . 
D 3 HOH 277 877 228 HOH HOH A . 
D 3 HOH 278 878 171 HOH HOH A . 
D 3 HOH 279 879 211 HOH HOH A . 
D 3 HOH 280 880 116 HOH HOH A . 
D 3 HOH 281 881 240 HOH HOH A . 
D 3 HOH 282 882 219 HOH HOH A . 
D 3 HOH 283 883 167 HOH HOH A . 
D 3 HOH 284 884 199 HOH HOH A . 
D 3 HOH 285 885 297 HOH HOH A . 
D 3 HOH 286 886 323 HOH HOH A . 
D 3 HOH 287 887 138 HOH HOH A . 
D 3 HOH 288 888 325 HOH HOH A . 
D 3 HOH 289 889 331 HOH HOH A . 
D 3 HOH 290 890 300 HOH HOH A . 
D 3 HOH 291 891 93  HOH HOH A . 
D 3 HOH 292 892 273 HOH HOH A . 
D 3 HOH 293 893 205 HOH HOH A . 
D 3 HOH 294 894 314 HOH HOH A . 
D 3 HOH 295 895 301 HOH HOH A . 
D 3 HOH 296 896 286 HOH HOH A . 
D 3 HOH 297 897 198 HOH HOH A . 
D 3 HOH 298 898 189 HOH HOH A . 
D 3 HOH 299 899 287 HOH HOH A . 
D 3 HOH 300 900 310 HOH HOH A . 
D 3 HOH 301 901 303 HOH HOH A . 
D 3 HOH 302 902 292 HOH HOH A . 
D 3 HOH 303 903 311 HOH HOH A . 
D 3 HOH 304 904 281 HOH HOH A . 
D 3 HOH 305 905 327 HOH HOH A . 
D 3 HOH 306 906 302 HOH HOH A . 
D 3 HOH 307 907 298 HOH HOH A . 
D 3 HOH 308 908 274 HOH HOH A . 
D 3 HOH 309 909 242 HOH HOH A . 
D 3 HOH 310 910 326 HOH HOH A . 
D 3 HOH 311 911 184 HOH HOH A . 
D 3 HOH 312 912 118 HOH HOH A . 
D 3 HOH 313 913 180 HOH HOH A . 
D 3 HOH 314 914 312 HOH HOH A . 
D 3 HOH 315 915 102 HOH HOH A . 
D 3 HOH 316 916 296 HOH HOH A . 
D 3 HOH 317 917 288 HOH HOH A . 
D 3 HOH 318 918 236 HOH HOH A . 
D 3 HOH 319 919 328 HOH HOH A . 
D 3 HOH 320 920 124 HOH HOH A . 
D 3 HOH 321 921 335 HOH HOH A . 
D 3 HOH 322 922 276 HOH HOH A . 
D 3 HOH 323 923 141 HOH HOH A . 
D 3 HOH 324 924 250 HOH HOH A . 
D 3 HOH 325 925 197 HOH HOH A . 
D 3 HOH 326 926 295 HOH HOH A . 
D 3 HOH 327 927 282 HOH HOH A . 
D 3 HOH 328 928 187 HOH HOH A . 
D 3 HOH 329 929 140 HOH HOH A . 
D 3 HOH 330 930 125 HOH HOH A . 
D 3 HOH 331 931 329 HOH HOH A . 
D 3 HOH 332 932 238 HOH HOH A . 
D 3 HOH 333 933 266 HOH HOH A . 
D 3 HOH 334 934 316 HOH HOH A . 
D 3 HOH 335 935 202 HOH HOH A . 
D 3 HOH 336 936 225 HOH HOH A . 
D 3 HOH 337 937 195 HOH HOH A . 
D 3 HOH 338 938 222 HOH HOH A . 
D 3 HOH 339 939 237 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.15.2_3472 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.578 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZVD 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     49.848 
_cell.length_a_esd                 ? 
_cell.length_b                     64.288 
_cell.length_b_esd                 ? 
_cell.length_c                     64.401 
_cell.length_c_esd                 ? 
_cell.volume                       206370.769 
_cell.volume_esd                   ? 
_cell.Z_PDB                        2 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZVD 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZVD 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.10 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          41.48 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '20% PEG 6000, 0.1M MES pH6.2' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     289 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97915 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL19U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97915 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL19U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          17.49 
_reflns.entry_id                                       8ZVD 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.72 
_reflns.d_resolution_low                               50 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     43288 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          18 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.990 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.72 
_reflns_shell.d_res_low                                     1.75 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2123 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.838 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               24.44 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ZVD 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.72 
_refine.ls_d_res_low                             28.79 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     42569 
_refine.ls_number_reflns_R_free                  1091 
_refine.ls_number_reflns_R_work                  41478 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.81 
_refine.ls_percent_reflns_R_free                 2.56 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1599 
_refine.ls_R_factor_R_free                       0.1936 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1590 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 18.9260 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1654 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.72 
_refine_hist.d_res_low                        28.79 
_refine_hist.number_atoms_solvent             339 
_refine_hist.number_atoms_total               3667 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3318 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         10 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0074 ? 3427 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7874 ? 4656 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0501 ? 512  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0048 ? 595  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 4.2045 ? 2828 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.72 1.80  . . 141 4404 83.98  . . . . 0.2090 . . . . . . . . . . . 0.2387 
'X-RAY DIFFRACTION' 1.80 1.89  . . 118 5233 98.69  . . . . 0.1820 . . . . . . . . . . . 0.2301 
'X-RAY DIFFRACTION' 1.89 2.01  . . 130 5273 100.00 . . . . 0.1676 . . . . . . . . . . . 0.1917 
'X-RAY DIFFRACTION' 2.01 2.16  . . 108 5308 99.98  . . . . 0.1622 . . . . . . . . . . . 0.2152 
'X-RAY DIFFRACTION' 2.16 2.38  . . 157 5273 100.00 . . . . 0.1559 . . . . . . . . . . . 0.2165 
'X-RAY DIFFRACTION' 2.38 2.73  . . 127 5303 99.96  . . . . 0.1534 . . . . . . . . . . . 0.1786 
'X-RAY DIFFRACTION' 2.73 3.43  . . 176 5278 100.00 . . . . 0.1524 . . . . . . . . . . . 0.1812 
'X-RAY DIFFRACTION' 3.43 28.79 . . 134 5406 99.80  . . . . 0.1532 . . . . . . . . . . . 0.1829 
# 
_struct.entry_id                     8ZVD 
_struct.title                        'ShosT with phosphate' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZVD 
_struct_keywords.text            'ShooT, Toxin, Phosphoribosyltransferase, pyrophosphatase, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A0H2Z117_ECOK1 
_struct_ref.pdbx_db_accession          A0A0H2Z117 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MNNMYLKAVIFSIADVVLPLTSNTQPQELKSRIDSELRKLFAFLSSKGIKVIFLTNKNRNVRTHDGIVTLDEYLKRKFPE
SIHFCRELDNNIPAKQTGKAIDFIMAALELKRNEMIYVGRSQEDLQAATNGNTLFINATWYEPVTEYGFQFSEPKEIARF
IDVFCLREQLWGWQGHFNEDVHYYALAPFSTYVPEFTMYSANARDLAKLSVGSPDFWIRYLGASIYFSGLSEGASFITTY
VGHNAEDPYKLANIMEHDLKGLAVSFKGKYLKDLFLRHTTAIKSQQARIAKQEVNITSQINTVNLNPAPIKNLITGERYT
NPPKLKGKKILVIDDFCTEGNAHETARMYLKAAGANVINISWLKTINRDVSICEPTRKIRPWEANTLDVDDINYVGTIGY
AENVTHGSAPQVLSEKIQQYDNWDWPQ
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8ZVD 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 6 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 432 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A0H2Z117 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  427 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       -2 
_struct_ref_seq.pdbx_auth_seq_align_end       424 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8ZVD GLY A 1 ? UNP A0A0H2Z117 ? ? 'expression tag' -7 1 
1 8ZVD ALA A 2 ? UNP A0A0H2Z117 ? ? 'expression tag' -6 2 
1 8ZVD SER A 3 ? UNP A0A0H2Z117 ? ? 'expression tag' -5 3 
1 8ZVD GLY A 4 ? UNP A0A0H2Z117 ? ? 'expression tag' -4 4 
1 8ZVD SER A 5 ? UNP A0A0H2Z117 ? ? 'expression tag' -3 5 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 240   ? 
1 MORE         -8    ? 
1 'SSA (A^2)'  18260 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 33  ? LYS A 52  ? GLU A 25  LYS A 44  1 ? 20 
HELX_P HELX_P2  AA2 LEU A 75  ? PHE A 83  ? LEU A 67  PHE A 75  1 ? 9  
HELX_P HELX_P3  AA3 GLU A 92  ? ASP A 94  ? GLU A 84  ASP A 86  5 ? 3  
HELX_P HELX_P4  AA4 ALA A 99  ? THR A 102 ? ALA A 91  THR A 94  5 ? 4  
HELX_P HELX_P5  AA5 GLY A 103 ? GLU A 114 ? GLY A 95  GLU A 106 1 ? 12 
HELX_P HELX_P6  AA6 LYS A 116 ? ASN A 118 ? LYS A 108 ASN A 110 5 ? 3  
HELX_P HELX_P7  AA7 SER A 126 ? GLY A 136 ? SER A 118 GLY A 128 1 ? 11 
HELX_P HELX_P8  AA8 GLU A 158 ? CYS A 170 ? GLU A 150 CYS A 162 1 ? 13 
HELX_P HELX_P9  AA9 SER A 218 ? SER A 233 ? SER A 210 SER A 225 1 ? 16 
HELX_P HELX_P10 AB1 TYR A 254 ? LYS A 272 ? TYR A 246 LYS A 264 1 ? 19 
HELX_P HELX_P11 AB2 ILE A 301 ? ASN A 306 ? ILE A 293 ASN A 298 1 ? 6  
HELX_P HELX_P12 AB3 GLY A 345 ? ALA A 358 ? GLY A 337 ALA A 350 1 ? 14 
HELX_P HELX_P13 AB4 ASP A 393 ? ASP A 395 ? ASP A 385 ASP A 387 5 ? 3  
HELX_P HELX_P14 AB5 TYR A 405 ? VAL A 409 ? TYR A 397 VAL A 401 5 ? 5  
HELX_P HELX_P15 AB6 PRO A 415 ? ASN A 427 ? PRO A 407 ASN A 419 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 2 ? 
AA3 ? 6 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 87  ? CYS A 90  ? ILE A 79  CYS A 82  
AA1 2 LYS A 55  ? THR A 60  ? LYS A 47  THR A 52  
AA1 3 ALA A 13  ? PHE A 16  ? ALA A 5   PHE A 8   
AA1 4 MET A 120 ? GLY A 124 ? MET A 112 GLY A 116 
AA1 5 LEU A 139 ? ALA A 143 ? LEU A 131 ALA A 135 
AA1 6 GLN A 155 ? PHE A 156 ? GLN A 147 PHE A 148 
AA2 1 ASN A 65  ? THR A 68  ? ASN A 57  THR A 60  
AA2 2 GLY A 71  ? THR A 74  ? GLY A 63  THR A 66  
AA3 1 TRP A 178 ? PHE A 182 ? TRP A 170 PHE A 174 
AA3 2 VAL A 186 ? PHE A 194 ? VAL A 178 PHE A 186 
AA3 3 ASN A 361 ? THR A 370 ? ASN A 353 THR A 362 
AA3 4 LYS A 334 ? CYS A 342 ? LYS A 326 CYS A 334 
AA3 5 ALA A 239 ? THR A 244 ? ALA A 231 THR A 236 
AA3 6 LYS A 274 ? LEU A 276 ? LYS A 266 LEU A 268 
AA4 1 PHE A 280 ? ARG A 282 ? PHE A 272 ARG A 274 
AA4 2 VAL A 308 ? LEU A 310 ? VAL A 300 LEU A 302 
AA5 1 VAL A 375 ? PRO A 380 ? VAL A 367 PRO A 372 
AA5 2 ILE A 397 ? ILE A 403 ? ILE A 389 ILE A 395 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 87  ? O ILE A 79  N PHE A 58  ? N PHE A 50  
AA1 2 3 O ILE A 57  ? O ILE A 49  N PHE A 16  ? N PHE A 8   
AA1 3 4 N ILE A 15  ? N ILE A 7   O VAL A 123 ? O VAL A 115 
AA1 4 5 N TYR A 122 ? N TYR A 114 O ILE A 141 ? O ILE A 133 
AA1 5 6 N ASN A 142 ? N ASN A 134 O PHE A 156 ? O PHE A 148 
AA2 1 2 N VAL A 66  ? N VAL A 58  O VAL A 73  ? O VAL A 65  
AA3 1 2 N GLY A 180 ? N GLY A 172 O TYR A 188 ? O TYR A 180 
AA3 2 3 N HIS A 187 ? N HIS A 179 O ASN A 364 ? O ASN A 356 
AA3 3 4 O ILE A 365 ? O ILE A 357 N VAL A 337 ? N VAL A 329 
AA3 4 5 O ILE A 338 ? O ILE A 330 N THR A 243 ? N THR A 235 
AA3 5 6 N ILE A 242 ? N ILE A 234 O LEU A 276 ? O LEU A 268 
AA4 1 2 N LEU A 281 ? N LEU A 273 O ASN A 309 ? O ASN A 301 
AA5 1 2 N GLU A 379 ? N GLU A 371 O ASN A 398 ? O ASN A 390 
# 
_pdbx_entry_details.entry_id                   8ZVD 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OE1 A GLU 77  ? ? O A HOH 601 ? ? 1.76 
2  1 OG1 A THR 21  ? ? O A HOH 602 ? ? 1.87 
3  1 O   A HOH 744 ? ? O A HOH 750 ? ? 2.04 
4  1 O   A HOH 657 ? ? O A HOH 887 ? ? 2.05 
5  1 O   A HOH 839 ? ? O A HOH 908 ? ? 2.05 
6  1 O   A HOH 840 ? ? O A HOH 934 ? ? 2.08 
7  1 O   A HOH 753 ? ? O A HOH 866 ? ? 2.09 
8  1 O   A HOH 881 ? ? O A HOH 887 ? ? 2.09 
9  1 O   A HOH 653 ? ? O A HOH 863 ? ? 2.10 
10 1 O   A HOH 899 ? ? O A HOH 926 ? ? 2.11 
11 1 O   A HOH 831 ? ? O A HOH 854 ? ? 2.12 
12 1 O   A HOH 932 ? ? O A HOH 939 ? ? 2.14 
13 1 O   A HOH 857 ? ? O A HOH 919 ? ? 2.16 
14 1 O   A HOH 903 ? ? O A HOH 917 ? ? 2.17 
15 1 O   A HOH 629 ? ? O A HOH 877 ? ? 2.18 
16 1 OG1 A THR 188 ? ? O A HOH 603 ? ? 2.18 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 OE2 A GLU 77  ? ? 1_555 HZ1 A LYS 375 ? ? 1_556 1.45 
2 1 O   A HOH 869 ? ? 1_555 O   A HOH 893 ? ? 2_645 2.13 
3 1 OE2 A GLU 77  ? ? 1_555 NZ  A LYS 375 ? ? 1_556 2.14 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CG 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_1             77 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_2             77 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.280 
_pdbx_validate_rmsd_bond.bond_target_value         1.515 
_pdbx_validate_rmsd_bond.bond_deviation            -0.235 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.015 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA  A GLU 77  ? ? CB A GLU 77  ? ? CG  A GLU 77  ? ? 98.67  113.40 -14.73 2.20 N 
2 1 OE1 A GLU 77  ? ? CD A GLU 77  ? ? OE2 A GLU 77  ? ? 133.62 123.30 10.32  1.20 N 
3 1 CD  A LYS 375 ? ? CE A LYS 375 ? ? NZ  A LYS 375 ? ? 97.28  111.70 -14.42 2.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 VAL A 13  ? ? -128.77 -70.81  
2 1 ASN A 53  ? ? -96.79  -61.06  
3 1 ARG A 117 ? ? -140.54 -43.06  
4 1 ASN A 175 ? ? 48.20   -145.99 
5 1 ASP A 244 ? ? -158.25 65.10   
6 1 THR A 335 ? ? -105.05 -81.43  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY -7  ? A GLY 1   
2  1 Y 1 A ALA -6  ? A ALA 2   
3  1 Y 1 A SER -5  ? A SER 3   
4  1 Y 1 A GLY -4  ? A GLY 4   
5  1 Y 1 A SER -3  ? A SER 5   
6  1 Y 1 A MET -2  ? A MET 6   
7  1 Y 1 A ASN -1  ? A ASN 7   
8  1 Y 1 A ASN 0   ? A ASN 8   
9  1 Y 1 A ALA 200 ? A ALA 208 
10 1 Y 1 A ARG 201 ? A ARG 209 
11 1 Y 1 A ASP 202 ? A ASP 210 
12 1 Y 1 A LEU 203 ? A LEU 211 
13 1 Y 1 A GLN 283 ? A GLN 291 
14 1 Y 1 A ALA 284 ? A ALA 292 
15 1 Y 1 A ARG 285 ? A ARG 293 
16 1 Y 1 A ILE 286 ? A ILE 294 
17 1 Y 1 A ALA 287 ? A ALA 295 
18 1 Y 1 A LYS 288 ? A LYS 296 
19 1 Y 1 A GLN 289 ? A GLN 297 
20 1 Y 1 A GLU 290 ? A GLU 298 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PO4 P    P N N 273 
PO4 O1   O N N 274 
PO4 O2   O N N 275 
PO4 O3   O N N 276 
PO4 O4   O N N 277 
PRO N    N N N 278 
PRO CA   C N S 279 
PRO C    C N N 280 
PRO O    O N N 281 
PRO CB   C N N 282 
PRO CG   C N N 283 
PRO CD   C N N 284 
PRO OXT  O N N 285 
PRO H    H N N 286 
PRO HA   H N N 287 
PRO HB2  H N N 288 
PRO HB3  H N N 289 
PRO HG2  H N N 290 
PRO HG3  H N N 291 
PRO HD2  H N N 292 
PRO HD3  H N N 293 
PRO HXT  H N N 294 
SER N    N N N 295 
SER CA   C N S 296 
SER C    C N N 297 
SER O    O N N 298 
SER CB   C N N 299 
SER OG   O N N 300 
SER OXT  O N N 301 
SER H    H N N 302 
SER H2   H N N 303 
SER HA   H N N 304 
SER HB2  H N N 305 
SER HB3  H N N 306 
SER HG   H N N 307 
SER HXT  H N N 308 
THR N    N N N 309 
THR CA   C N S 310 
THR C    C N N 311 
THR O    O N N 312 
THR CB   C N R 313 
THR OG1  O N N 314 
THR CG2  C N N 315 
THR OXT  O N N 316 
THR H    H N N 317 
THR H2   H N N 318 
THR HA   H N N 319 
THR HB   H N N 320 
THR HG1  H N N 321 
THR HG21 H N N 322 
THR HG22 H N N 323 
THR HG23 H N N 324 
THR HXT  H N N 325 
TRP N    N N N 326 
TRP CA   C N S 327 
TRP C    C N N 328 
TRP O    O N N 329 
TRP CB   C N N 330 
TRP CG   C Y N 331 
TRP CD1  C Y N 332 
TRP CD2  C Y N 333 
TRP NE1  N Y N 334 
TRP CE2  C Y N 335 
TRP CE3  C Y N 336 
TRP CZ2  C Y N 337 
TRP CZ3  C Y N 338 
TRP CH2  C Y N 339 
TRP OXT  O N N 340 
TRP H    H N N 341 
TRP H2   H N N 342 
TRP HA   H N N 343 
TRP HB2  H N N 344 
TRP HB3  H N N 345 
TRP HD1  H N N 346 
TRP HE1  H N N 347 
TRP HE3  H N N 348 
TRP HZ2  H N N 349 
TRP HZ3  H N N 350 
TRP HH2  H N N 351 
TRP HXT  H N N 352 
TYR N    N N N 353 
TYR CA   C N S 354 
TYR C    C N N 355 
TYR O    O N N 356 
TYR CB   C N N 357 
TYR CG   C Y N 358 
TYR CD1  C Y N 359 
TYR CD2  C Y N 360 
TYR CE1  C Y N 361 
TYR CE2  C Y N 362 
TYR CZ   C Y N 363 
TYR OH   O N N 364 
TYR OXT  O N N 365 
TYR H    H N N 366 
TYR H2   H N N 367 
TYR HA   H N N 368 
TYR HB2  H N N 369 
TYR HB3  H N N 370 
TYR HD1  H N N 371 
TYR HD2  H N N 372 
TYR HE1  H N N 373 
TYR HE2  H N N 374 
TYR HH   H N N 375 
TYR HXT  H N N 376 
VAL N    N N N 377 
VAL CA   C N S 378 
VAL C    C N N 379 
VAL O    O N N 380 
VAL CB   C N N 381 
VAL CG1  C N N 382 
VAL CG2  C N N 383 
VAL OXT  O N N 384 
VAL H    H N N 385 
VAL H2   H N N 386 
VAL HA   H N N 387 
VAL HB   H N N 388 
VAL HG11 H N N 389 
VAL HG12 H N N 390 
VAL HG13 H N N 391 
VAL HG21 H N N 392 
VAL HG22 H N N 393 
VAL HG23 H N N 394 
VAL HXT  H N N 395 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PO4 P   O1   doub N N 260 
PO4 P   O2   sing N N 261 
PO4 P   O3   sing N N 262 
PO4 P   O4   sing N N 263 
PRO N   CA   sing N N 264 
PRO N   CD   sing N N 265 
PRO N   H    sing N N 266 
PRO CA  C    sing N N 267 
PRO CA  CB   sing N N 268 
PRO CA  HA   sing N N 269 
PRO C   O    doub N N 270 
PRO C   OXT  sing N N 271 
PRO CB  CG   sing N N 272 
PRO CB  HB2  sing N N 273 
PRO CB  HB3  sing N N 274 
PRO CG  CD   sing N N 275 
PRO CG  HG2  sing N N 276 
PRO CG  HG3  sing N N 277 
PRO CD  HD2  sing N N 278 
PRO CD  HD3  sing N N 279 
PRO OXT HXT  sing N N 280 
SER N   CA   sing N N 281 
SER N   H    sing N N 282 
SER N   H2   sing N N 283 
SER CA  C    sing N N 284 
SER CA  CB   sing N N 285 
SER CA  HA   sing N N 286 
SER C   O    doub N N 287 
SER C   OXT  sing N N 288 
SER CB  OG   sing N N 289 
SER CB  HB2  sing N N 290 
SER CB  HB3  sing N N 291 
SER OG  HG   sing N N 292 
SER OXT HXT  sing N N 293 
THR N   CA   sing N N 294 
THR N   H    sing N N 295 
THR N   H2   sing N N 296 
THR CA  C    sing N N 297 
THR CA  CB   sing N N 298 
THR CA  HA   sing N N 299 
THR C   O    doub N N 300 
THR C   OXT  sing N N 301 
THR CB  OG1  sing N N 302 
THR CB  CG2  sing N N 303 
THR CB  HB   sing N N 304 
THR OG1 HG1  sing N N 305 
THR CG2 HG21 sing N N 306 
THR CG2 HG22 sing N N 307 
THR CG2 HG23 sing N N 308 
THR OXT HXT  sing N N 309 
TRP N   CA   sing N N 310 
TRP N   H    sing N N 311 
TRP N   H2   sing N N 312 
TRP CA  C    sing N N 313 
TRP CA  CB   sing N N 314 
TRP CA  HA   sing N N 315 
TRP C   O    doub N N 316 
TRP C   OXT  sing N N 317 
TRP CB  CG   sing N N 318 
TRP CB  HB2  sing N N 319 
TRP CB  HB3  sing N N 320 
TRP CG  CD1  doub Y N 321 
TRP CG  CD2  sing Y N 322 
TRP CD1 NE1  sing Y N 323 
TRP CD1 HD1  sing N N 324 
TRP CD2 CE2  doub Y N 325 
TRP CD2 CE3  sing Y N 326 
TRP NE1 CE2  sing Y N 327 
TRP NE1 HE1  sing N N 328 
TRP CE2 CZ2  sing Y N 329 
TRP CE3 CZ3  doub Y N 330 
TRP CE3 HE3  sing N N 331 
TRP CZ2 CH2  doub Y N 332 
TRP CZ2 HZ2  sing N N 333 
TRP CZ3 CH2  sing Y N 334 
TRP CZ3 HZ3  sing N N 335 
TRP CH2 HH2  sing N N 336 
TRP OXT HXT  sing N N 337 
TYR N   CA   sing N N 338 
TYR N   H    sing N N 339 
TYR N   H2   sing N N 340 
TYR CA  C    sing N N 341 
TYR CA  CB   sing N N 342 
TYR CA  HA   sing N N 343 
TYR C   O    doub N N 344 
TYR C   OXT  sing N N 345 
TYR CB  CG   sing N N 346 
TYR CB  HB2  sing N N 347 
TYR CB  HB3  sing N N 348 
TYR CG  CD1  doub Y N 349 
TYR CG  CD2  sing Y N 350 
TYR CD1 CE1  sing Y N 351 
TYR CD1 HD1  sing N N 352 
TYR CD2 CE2  doub Y N 353 
TYR CD2 HD2  sing N N 354 
TYR CE1 CZ   doub Y N 355 
TYR CE1 HE1  sing N N 356 
TYR CE2 CZ   sing Y N 357 
TYR CE2 HE2  sing N N 358 
TYR CZ  OH   sing N N 359 
TYR OH  HH   sing N N 360 
TYR OXT HXT  sing N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8ZVD 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.020061 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000202 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015555 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.015528 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . MET A 1 9   ? 22.13693  8.99515   21.20952  1.000 51.04948  ? 1   MET A N    1 
ATOM   2    C CA   . MET A 1 9   ? 20.83714  8.28487   21.15435  1.000 25.98559  ? 1   MET A CA   1 
ATOM   3    C C    . MET A 1 9   ? 20.05555  8.67228   19.89886  1.000 32.46086  ? 1   MET A C    1 
ATOM   4    O O    . MET A 1 9   ? 19.91904  9.85123   19.56825  1.000 41.49978  ? 1   MET A O    1 
ATOM   5    C CB   . MET A 1 9   ? 19.99313  8.60553   22.39669  1.000 42.73965  ? 1   MET A CB   1 
ATOM   6    C CG   . MET A 1 9   ? 19.86438  7.46915   23.39455  1.000 45.95879  ? 1   MET A CG   1 
ATOM   7    S SD   . MET A 1 9   ? 18.61341  7.77306   24.66240  1.000 58.61718  ? 1   MET A SD   1 
ATOM   8    C CE   . MET A 1 9   ? 19.16511  9.34908   25.31541  1.000 45.56719  ? 1   MET A CE   1 
ATOM   9    H H    . MET A 1 9   ? 22.79466  8.40318   21.30473  1.000 61.27639  ? 1   MET A H    1 
ATOM   10   H HA   . MET A 1 9   ? 21.01017  7.33050   21.14275  1.000 31.19973  ? 1   MET A HA   1 
ATOM   11   H HB2  . MET A 1 9   ? 20.40022  9.35447   22.85957  1.000 51.30460  ? 1   MET A HB2  1 
ATOM   12   H HB3  . MET A 1 9   ? 19.09787  8.84138   22.10721  1.000 51.30460  ? 1   MET A HB3  1 
ATOM   13   H HG2  . MET A 1 9   ? 19.61704  6.66033   22.91963  1.000 55.16757  ? 1   MET A HG2  1 
ATOM   14   H HG3  . MET A 1 9   ? 20.71666  7.34447   23.84062  1.000 55.16757  ? 1   MET A HG3  1 
ATOM   15   H HE1  . MET A 1 9   ? 18.84589  9.44255   26.22660  1.000 54.69765  ? 1   MET A HE1  1 
ATOM   16   H HE2  . MET A 1 9   ? 20.13464  9.37524   25.30026  1.000 54.69765  ? 1   MET A HE2  1 
ATOM   17   H HE3  . MET A 1 9   ? 18.80632  10.06224  24.76443  1.000 54.69765  ? 1   MET A HE3  1 
ATOM   18   N N    . TYR A 1 10  ? 19.55213  7.66829   19.19122  1.000 20.64648  ? 2   TYR A N    1 
ATOM   19   C CA   . TYR A 1 10  ? 18.54783  7.90030   18.16121  1.000 16.10841  ? 2   TYR A CA   1 
ATOM   20   C C    . TYR A 1 10  ? 17.14966  7.94090   18.75273  1.000 20.10650  ? 2   TYR A C    1 
ATOM   21   O O    . TYR A 1 10  ? 16.35039  8.82109   18.41138  1.000 19.02092  ? 2   TYR A O    1 
ATOM   22   C CB   . TYR A 1 10  ? 18.60372  6.80480   17.09798  1.000 14.80515  ? 2   TYR A CB   1 
ATOM   23   C CG   . TYR A 1 10  ? 19.85768  6.85816   16.26026  1.000 14.13329  ? 2   TYR A CG   1 
ATOM   24   C CD1  . TYR A 1 10  ? 20.11129  7.93427   15.43015  1.000 22.41156  ? 2   TYR A CD1  1 
ATOM   25   C CD2  . TYR A 1 10  ? 20.79027  5.83427   16.30704  1.000 18.50532  ? 2   TYR A CD2  1 
ATOM   26   C CE1  . TYR A 1 10  ? 21.26787  7.98957   14.66654  1.000 24.43454  ? 2   TYR A CE1  1 
ATOM   27   C CE2  . TYR A 1 10  ? 21.94534  5.88611   15.55054  1.000 19.03259  ? 2   TYR A CE2  1 
ATOM   28   C CZ   . TYR A 1 10  ? 22.17717  6.96048   14.73679  1.000 23.23728  ? 2   TYR A CZ   1 
ATOM   29   O OH   . TYR A 1 10  ? 23.32936  7.02058   13.97538  1.000 27.46520  ? 2   TYR A OH   1 
ATOM   30   H H    . TYR A 1 10  ? 19.77560  6.84353   19.28836  1.000 24.79280  ? 2   TYR A H    1 
ATOM   31   H HA   . TYR A 1 10  ? 18.73853  8.74632   17.72671  1.000 19.34711  ? 2   TYR A HA   1 
ATOM   32   H HB2  . TYR A 1 10  ? 18.57299  5.93972   17.53568  1.000 17.78321  ? 2   TYR A HB2  1 
ATOM   33   H HB3  . TYR A 1 10  ? 17.84297  6.90345   16.50432  1.000 17.78321  ? 2   TYR A HB3  1 
ATOM   34   H HD1  . TYR A 1 10  ? 19.49740  8.63128   15.38305  1.000 26.91089  ? 2   TYR A HD1  1 
ATOM   35   H HD2  . TYR A 1 10  ? 20.63616  5.10009   16.85670  1.000 22.22340  ? 2   TYR A HD2  1 
ATOM   36   H HE1  . TYR A 1 10  ? 21.42734  8.71790   14.11066  1.000 29.33847  ? 2   TYR A HE1  1 
ATOM   37   H HE2  . TYR A 1 10  ? 22.56327  5.19248   15.59461  1.000 22.85613  ? 2   TYR A HE2  1 
ATOM   38   H HH   . TYR A 1 10  ? 23.47852  6.27394   13.62057  1.000 32.97527  ? 2   TYR A HH   1 
ATOM   39   N N    . LEU A 1 11  ? 16.85209  6.99993   19.64002  1.000 14.82783  ? 3   LEU A N    1 
ATOM   40   C CA   . LEU A 1 11  ? 15.52964  6.86141   20.23062  1.000 11.18511  ? 3   LEU A CA   1 
ATOM   41   C C    . LEU A 1 11  ? 15.52774  7.49724   21.61390  1.000 10.69623  ? 3   LEU A C    1 
ATOM   42   O O    . LEU A 1 11  ? 16.29168  7.08863   22.49384  1.000 13.99639  ? 3   LEU A O    1 
ATOM   43   C CB   . LEU A 1 11  ? 15.12777  5.39209   20.32398  1.000 10.05127  ? 3   LEU A CB   1 
ATOM   44   C CG   . LEU A 1 11  ? 13.74027  5.10665   20.91350  1.000 13.12886  ? 3   LEU A CG   1 
ATOM   45   C CD1  . LEU A 1 11  ? 12.63752  5.70375   20.05487  1.000 13.83054  ? 3   LEU A CD1  1 
ATOM   46   C CD2  . LEU A 1 11  ? 13.52895  3.62279   21.07236  1.000 12.90310  ? 3   LEU A CD2  1 
ATOM   47   H H    . LEU A 1 11  ? 17.41542  6.41476   19.92257  1.000 17.81042  ? 3   LEU A H    1 
ATOM   48   H HA   . LEU A 1 11  ? 14.88284  7.32586   19.67669  1.000 13.43915  ? 3   LEU A HA   1 
ATOM   49   H HB2  . LEU A 1 11  ? 15.14137  5.01804   19.42910  1.000 12.07855  ? 3   LEU A HB2  1 
ATOM   50   H HB3  . LEU A 1 11  ? 15.77611  4.93686   20.88373  1.000 12.07855  ? 3   LEU A HB3  1 
ATOM   51   H HG   . LEU A 1 11  ? 13.69101  5.52317   21.78814  1.000 15.77166  ? 3   LEU A HG   1 
ATOM   52   H HD11 . LEU A 1 11  ? 11.77733  5.43689   20.41507  1.000 16.61367  ? 3   LEU A HD11 1 
ATOM   53   H HD12 . LEU A 1 11  ? 12.71591  6.67049   20.06751  1.000 16.61367  ? 3   LEU A HD12 1 
ATOM   54   H HD13 . LEU A 1 11  ? 12.73193  5.37608   19.14679  1.000 16.61367  ? 3   LEU A HD13 1 
ATOM   55   H HD21 . LEU A 1 11  ? 12.62910  3.46507   21.39838  1.000 15.50075  ? 3   LEU A HD21 1 
ATOM   56   H HD22 . LEU A 1 11  ? 13.64890  3.19274   20.21122  1.000 15.50075  ? 3   LEU A HD22 1 
ATOM   57   H HD23 . LEU A 1 11  ? 14.17603  3.27785   21.70735  1.000 15.50075  ? 3   LEU A HD23 1 
ATOM   58   N N    . LYS A 1 12  ? 14.65583  8.47694   21.81253  1.000 10.45752  ? 4   LYS A N    1 
ATOM   59   C CA   . LYS A 1 12  ? 14.59942  9.19682   23.07801  1.000 10.93053  ? 4   LYS A CA   1 
ATOM   60   C C    . LYS A 1 12  ? 13.25550  9.08613   23.78299  1.000 9.54227   ? 4   LYS A C    1 
ATOM   61   O O    . LYS A 1 12  ? 13.17487  9.38843   24.98434  1.000 11.71948  ? 4   LYS A O    1 
ATOM   62   C CB   . LYS A 1 12  ? 14.94777  10.67493  22.85621  1.000 13.96802  ? 4   LYS A CB   1 
ATOM   63   C CG   . LYS A 1 12  ? 16.40413  10.87771  22.43910  1.000 18.06144  ? 4   LYS A CG   1 
ATOM   64   C CD   . LYS A 1 12  ? 16.73390  12.33465  22.22573  1.000 30.37610  ? 4   LYS A CD   1 
ATOM   65   C CE   . LYS A 1 12  ? 18.21170  12.48894  21.85872  1.000 31.98080  ? 4   LYS A CE   1 
ATOM   66   N NZ   . LYS A 1 12  ? 18.53190  13.89278  21.45421  1.000 53.91594  ? 4   LYS A NZ   1 
ATOM   67   H H    . LYS A 1 12  ? 14.08446  8.74441   21.22808  1.000 12.56604  ? 4   LYS A H    1 
ATOM   68   H HA   . LYS A 1 12  ? 15.26503  8.83021   23.68089  1.000 13.13365  ? 4   LYS A HA   1 
ATOM   69   H HB2  . LYS A 1 12  ? 14.38097  11.03179  22.15458  1.000 16.77864  ? 4   LYS A HB2  1 
ATOM   70   H HB3  . LYS A 1 12  ? 14.80023  11.16217  23.68188  1.000 16.77864  ? 4   LYS A HB3  1 
ATOM   71   H HG2  . LYS A 1 12  ? 16.98633  10.53437  23.13485  1.000 21.69075  ? 4   LYS A HG2  1 
ATOM   72   H HG3  . LYS A 1 12  ? 16.56681  10.40564  21.60748  1.000 21.69075  ? 4   LYS A HG3  1 
ATOM   73   H HD2  . LYS A 1 12  ? 16.19483  12.68920  21.50144  1.000 36.46835  ? 4   LYS A HD2  1 
ATOM   74   H HD3  . LYS A 1 12  ? 16.56231  12.83149  23.04096  1.000 36.46835  ? 4   LYS A HD3  1 
ATOM   75   H HE2  . LYS A 1 12  ? 18.75886  12.26026  22.62633  1.000 38.39398  ? 4   LYS A HE2  1 
ATOM   76   H HE3  . LYS A 1 12  ? 18.42104  11.90195  21.11540  1.000 38.39398  ? 4   LYS A HE3  1 
ATOM   77   H HZ1  . LYS A 1 12  ? 19.41138  13.98846  21.35696  1.000 64.71616  ? 4   LYS A HZ1  1 
ATOM   78   H HZ2  . LYS A 1 12  ? 18.13326  14.08554  20.68218  1.000 64.71616  ? 4   LYS A HZ2  1 
ATOM   79   H HZ3  . LYS A 1 12  ? 18.24655  14.46147  22.07652  1.000 64.71616  ? 4   LYS A HZ3  1 
ATOM   80   N N    . ALA A 1 13  ? 12.21597  8.62339   23.09574  1.000 12.44248  ? 5   ALA A N    1 
ATOM   81   C CA   . ALA A 1 13  ? 10.92340  8.43557   23.73523  1.000 13.13647  ? 5   ALA A CA   1 
ATOM   82   C C    . ALA A 1 13  ? 10.10740  7.40674   22.96949  1.000 9.79593   ? 5   ALA A C    1 
ATOM   83   O O    . ALA A 1 13  ? 10.12653  7.37055   21.74001  1.000 9.33674   ? 5   ALA A O    1 
ATOM   84   C CB   . ALA A 1 13  ? 10.14364  9.75243   23.81646  1.000 12.77275  ? 5   ALA A CB   1 
ATOM   85   H H    . ALA A 1 13  ? 12.23575  8.41257   22.26221  1.000 14.94800  ? 5   ALA A H    1 
ATOM   86   H HA   . ALA A 1 13  ? 11.07127  8.09574   24.63163  1.000 15.78079  ? 5   ALA A HA   1 
ATOM   87   H HB1  . ALA A 1 13  ? 9.30204   9.59352   24.27182  1.000 15.34432  ? 5   ALA A HB1  1 
ATOM   88   H HB2  . ALA A 1 13  ? 10.66957  10.40092  24.31019  1.000 15.34432  ? 5   ALA A HB2  1 
ATOM   89   H HB3  . ALA A 1 13  ? 9.97729   10.07691  22.91761  1.000 15.34432  ? 5   ALA A HB3  1 
ATOM   90   N N    . VAL A 1 14  ? 9.33773   6.61914   23.70075  1.000 9.53866   ? 6   VAL A N    1 
ATOM   91   C CA   . VAL A 1 14  ? 8.40532   5.67235   23.10437  1.000 8.63413   ? 6   VAL A CA   1 
ATOM   92   C C    . VAL A 1 14  ? 7.01593   6.07339   23.56728  1.000 10.54891  ? 6   VAL A C    1 
ATOM   93   O O    . VAL A 1 14  ? 6.77398   6.17374   24.77576  1.000 11.14113  ? 6   VAL A O    1 
ATOM   94   C CB   . VAL A 1 14  ? 8.71046   4.22756   23.50571  1.000 9.21089   ? 6   VAL A CB   1 
ATOM   95   C CG1  . VAL A 1 14  ? 7.72723   3.28141   22.82099  1.000 10.82503  ? 6   VAL A CG1  1 
ATOM   96   C CG2  . VAL A 1 14  ? 10.12450  3.87276   23.09755  1.000 8.73551   ? 6   VAL A CG2  1 
ATOM   97   H H    . VAL A 1 14  ? 9.33615   6.61327   24.56072  1.000 11.46342  ? 6   VAL A H    1 
ATOM   98   H HA   . VAL A 1 14  ? 8.45442   5.73068   22.13737  1.000 10.37798  ? 6   VAL A HA   1 
ATOM   99   H HB   . VAL A 1 14  ? 8.62312   4.13309   24.46714  1.000 11.07009  ? 6   VAL A HB   1 
ATOM   100  H HG11 . VAL A 1 14  ? 7.95954   2.36709   23.04670  1.000 13.00706  ? 6   VAL A HG11 1 
ATOM   101  H HG12 . VAL A 1 14  ? 6.82973   3.48065   23.13032  1.000 13.00706  ? 6   VAL A HG12 1 
ATOM   102  H HG13 . VAL A 1 14  ? 7.78228   3.40934   21.86104  1.000 13.00706  ? 6   VAL A HG13 1 
ATOM   103  H HG21 . VAL A 1 14  ? 10.28581  2.93751   23.29804  1.000 10.49963  ? 6   VAL A HG21 1 
ATOM   104  H HG22 . VAL A 1 14  ? 10.22724  4.02953   22.14584  1.000 10.49963  ? 6   VAL A HG22 1 
ATOM   105  H HG23 . VAL A 1 14  ? 10.74534  4.42920   23.59337  1.000 10.49963  ? 6   VAL A HG23 1 
ATOM   106  N N    . ILE A 1 15  ? 6.11630   6.29661   22.61181  1.000 9.55584   ? 7   ILE A N    1 
ATOM   107  C CA   . ILE A 1 15  ? 4.71115   6.59694   22.88370  1.000 9.05432   ? 7   ILE A CA   1 
ATOM   108  C C    . ILE A 1 15  ? 3.93945   5.29132   22.93329  1.000 11.78430  ? 7   ILE A C    1 
ATOM   109  O O    . ILE A 1 15  ? 4.10276   4.43520   22.05454  1.000 13.24018  ? 7   ILE A O    1 
ATOM   110  C CB   . ILE A 1 15  ? 4.13142   7.51944   21.79940  1.000 9.57678   ? 7   ILE A CB   1 
ATOM   111  C CG1  . ILE A 1 15  ? 4.87546   8.85413   21.76045  1.000 12.69614  ? 7   ILE A CG1  1 
ATOM   112  C CG2  . ILE A 1 15  ? 2.62473   7.74190   22.01883  1.000 12.34311  ? 7   ILE A CG2  1 
ATOM   113  C CD1  . ILE A 1 15  ? 4.62627   9.63455   20.46260  1.000 13.54065  ? 7   ILE A CD1  1 
ATOM   114  H H    . ILE A 1 15  ? 6.30045   6.27928   21.77194  1.000 11.48403  ? 7   ILE A H    1 
ATOM   115  H HA   . ILE A 1 15  ? 4.63826   7.03924   23.74391  1.000 10.88220  ? 7   ILE A HA   1 
ATOM   116  H HB   . ILE A 1 15  ? 4.25392   7.08183   20.94243  1.000 11.50916  ? 7   ILE A HB   1 
ATOM   117  H HG12 . ILE A 1 15  ? 4.57830   9.40314   22.50286  1.000 15.25240  ? 7   ILE A HG12 1 
ATOM   118  H HG13 . ILE A 1 15  ? 5.82823   8.68678   21.83211  1.000 15.25240  ? 7   ILE A HG13 1 
ATOM   119  H HG21 . ILE A 1 15  ? 2.31165   8.41823   21.39797  1.000 14.82876  ? 7   ILE A HG21 1 
ATOM   120  H HG22 . ILE A 1 15  ? 2.15618   6.90708   21.86249  1.000 14.82876  ? 7   ILE A HG22 1 
ATOM   121  H HG23 . ILE A 1 15  ? 2.47870   8.03736   22.93112  1.000 14.82876  ? 7   ILE A HG23 1 
ATOM   122  H HD11 . ILE A 1 15  ? 5.14081   10.45654  20.48463  1.000 16.26580  ? 7   ILE A HD11 1 
ATOM   123  H HD12 . ILE A 1 15  ? 4.90376   9.09072   19.70885  1.000 16.26580  ? 7   ILE A HD12 1 
ATOM   124  H HD13 . ILE A 1 15  ? 3.68042   9.83815   20.39318  1.000 16.26580  ? 7   ILE A HD13 1 
ATOM   125  N N    . PHE A 1 16  ? 3.07953   5.14401   23.94435  1.000 11.24960  ? 8   PHE A N    1 
ATOM   126  C CA   . PHE A 1 16  ? 2.18353   4.00165   24.07383  1.000 8.97097   ? 8   PHE A CA   1 
ATOM   127  C C    . PHE A 1 16  ? 0.74541   4.50715   24.08591  1.000 13.19835  ? 8   PHE A C    1 
ATOM   128  O O    . PHE A 1 16  ? 0.41658   5.43043   24.84043  1.000 11.69081  ? 8   PHE A O    1 
ATOM   129  C CB   . PHE A 1 16  ? 2.46419   3.20278   25.35768  1.000 11.38129  ? 8   PHE A CB   1 
ATOM   130  C CG   . PHE A 1 16  ? 3.80230   2.54249   25.37344  1.000 11.28220  ? 8   PHE A CG   1 
ATOM   131  C CD1  . PHE A 1 16  ? 4.92976   3.24923   25.75163  1.000 13.63689  ? 8   PHE A CD1  1 
ATOM   132  C CD2  . PHE A 1 16  ? 3.93696   1.21576   25.00279  1.000 12.18589  ? 8   PHE A CD2  1 
ATOM   133  C CE1  . PHE A 1 16  ? 6.16857   2.63379   25.74735  1.000 11.51275  ? 8   PHE A CE1  1 
ATOM   134  C CE2  . PHE A 1 16  ? 5.17018   0.60840   24.98224  1.000 8.96232   ? 8   PHE A CE2  1 
ATOM   135  C CZ   . PHE A 1 16  ? 6.28206   1.31258   25.35684  1.000 10.74150  ? 8   PHE A CZ   1 
ATOM   136  H H    . PHE A 1 16  ? 2.99759   5.71218   24.58472  1.000 13.51655  ? 8   PHE A H    1 
ATOM   137  H HA   . PHE A 1 16  ? 2.30833   3.40842   23.31660  1.000 10.78219  ? 8   PHE A HA   1 
ATOM   138  H HB2  . PHE A 1 16  ? 2.42271   3.80622   26.11599  1.000 13.67458  ? 8   PHE A HB2  1 
ATOM   139  H HB3  . PHE A 1 16  ? 1.79105   2.51018   25.44763  1.000 13.67458  ? 8   PHE A HB3  1 
ATOM   140  H HD1  . PHE A 1 16  ? 4.85471   4.13969   26.00922  1.000 16.38129  ? 8   PHE A HD1  1 
ATOM   141  H HD2  . PHE A 1 16  ? 3.18202   0.72791   24.76411  1.000 14.64009  ? 8   PHE A HD2  1 
ATOM   142  H HE1  . PHE A 1 16  ? 6.92482   3.10869   26.00708  1.000 13.83233  ? 8   PHE A HE1  1 
ATOM   143  H HE2  . PHE A 1 16  ? 5.24852   -0.27876  24.71443  1.000 10.77181  ? 8   PHE A HE2  1 
ATOM   144  H HZ   . PHE A 1 16  ? 7.11613   0.90131   25.34870  1.000 12.90682  ? 8   PHE A HZ   1 
ATOM   145  N N    . SER A 1 17  ? -0.09583  3.92347   23.23652  1.000 10.84746  ? 9   SER A N    1 
ATOM   146  C CA   . SER A 1 17  ? -1.53551  4.11179   23.32516  1.000 12.11110  ? 9   SER A CA   1 
ATOM   147  C C    . SER A 1 17  ? -2.12024  3.00637   24.19739  1.000 13.49914  ? 9   SER A C    1 
ATOM   148  O O    . SER A 1 17  ? -1.44207  2.04408   24.56513  1.000 16.02157  ? 9   SER A O    1 
ATOM   149  C CB   . SER A 1 17  ? -2.16583  4.13299   21.92917  1.000 12.76513  ? 9   SER A CB   1 
ATOM   150  O OG   . SER A 1 17  ? -1.77992  3.00257   21.18129  1.000 18.13249  ? 9   SER A OG   1 
ATOM   151  H H    . SER A 1 17  ? 0.14837   3.40779   22.59306  1.000 13.03398  ? 9   SER A H    1 
ATOM   152  H HA   . SER A 1 17  ? -1.74438  4.96783   23.73072  1.000 14.55034  ? 9   SER A HA   1 
ATOM   153  H HB2  . SER A 1 17  ? -3.13157  4.13571   22.01986  1.000 15.33518  ? 9   SER A HB2  1 
ATOM   154  H HB3  . SER A 1 17  ? -1.87402  4.93268   21.46415  1.000 15.33518  ? 9   SER A HB3  1 
ATOM   155  H HG   . SER A 1 17  ? -0.95687  3.03445   21.01643  1.000 21.77601  ? 9   SER A HG   1 
ATOM   156  N N    . ILE A 1 18  ? -3.39331  3.15258   24.54394  1.000 12.73365  ? 10  ILE A N    1 
ATOM   157  C CA   . ILE A 1 18  ? -3.99838  2.27368   25.53809  1.000 15.17425  ? 10  ILE A CA   1 
ATOM   158  C C    . ILE A 1 18  ? -4.70304  1.09382   24.89344  1.000 12.68222  ? 10  ILE A C    1 
ATOM   159  O O    . ILE A 1 18  ? -4.48725  -0.05192  25.29244  1.000 13.97621  ? 10  ILE A O    1 
ATOM   160  C CB   . ILE A 1 18  ? -4.97212  3.07257   26.42603  1.000 16.37668  ? 10  ILE A CB   1 
ATOM   161  C CG1  . ILE A 1 18  ? -4.22459  4.20347   27.12897  1.000 18.38942  ? 10  ILE A CG1  1 
ATOM   162  C CG2  . ILE A 1 18  ? -5.63285  2.16031   27.43516  1.000 19.60646  ? 10  ILE A CG2  1 
ATOM   163  C CD1  . ILE A 1 18  ? -3.07726  3.74351   27.97540  1.000 16.13981  ? 10  ILE A CD1  1 
ATOM   164  H H    . ILE A 1 18  ? -3.92372  3.74764   24.22117  1.000 15.29740  ? 10  ILE A H    1 
ATOM   165  H HA   . ILE A 1 18  ? -3.28677  1.92502   26.09751  1.000 18.22612  ? 10  ILE A HA   1 
ATOM   166  H HB   . ILE A 1 18  ? -5.66340  3.45801   25.86525  1.000 19.66904  ? 10  ILE A HB   1 
ATOM   167  H HG12 . ILE A 1 18  ? -3.87163  4.80743   26.45699  1.000 22.08433  ? 10  ILE A HG12 1 
ATOM   168  H HG13 . ILE A 1 18  ? -4.84577  4.67523   27.70559  1.000 22.08433  ? 10  ILE A HG13 1 
ATOM   169  H HG21 . ILE A 1 18  ? -6.07086  2.70130   28.11071  1.000 23.54477  ? 10  ILE A HG21 1 
ATOM   170  H HG22 . ILE A 1 18  ? -6.28634  1.60656   26.97996  1.000 23.54477  ? 10  ILE A HG22 1 
ATOM   171  H HG23 . ILE A 1 18  ? -4.95527  1.60157   27.84698  1.000 23.54477  ? 10  ILE A HG23 1 
ATOM   172  H HD11 . ILE A 1 18  ? -2.75012  4.49243   28.49789  1.000 19.38480  ? 10  ILE A HD11 1 
ATOM   173  H HD12 . ILE A 1 18  ? -3.38342  3.03714   28.56550  1.000 19.38480  ? 10  ILE A HD12 1 
ATOM   174  H HD13 . ILE A 1 18  ? -2.37268  3.41007   27.39809  1.000 19.38480  ? 10  ILE A HD13 1 
ATOM   175  N N    . ALA A 1 19  ? -5.55287  1.35320   23.89958  1.000 18.13035  ? 11  ALA A N    1 
ATOM   176  C CA   . ALA A 1 19  ? -6.49880  0.34630   23.42461  1.000 19.88276  ? 11  ALA A CA   1 
ATOM   177  C C    . ALA A 1 19  ? -5.78210  -0.87929  22.87033  1.000 13.01796  ? 11  ALA A C    1 
ATOM   178  O O    . ALA A 1 19  ? -5.05955  -0.78816  21.87127  1.000 13.25409  ? 11  ALA A O    1 
ATOM   179  C CB   . ALA A 1 19  ? -7.40652  0.94563   22.35196  1.000 21.08225  ? 11  ALA A CB   1 
ATOM   180  H H    . ALA A 1 19  ? -5.60140  2.10453   23.48395  1.000 21.77344  ? 11  ALA A H    1 
ATOM   181  H HA   . ALA A 1 19  ? -7.04051  0.06186   24.17730  1.000 23.87634  ? 11  ALA A HA   1 
ATOM   182  H HB1  . ALA A 1 19  ? -8.02205  0.26314   22.04176  1.000 25.31573  ? 11  ALA A HB1  1 
ATOM   183  H HB2  . ALA A 1 19  ? -7.90063  1.68739   22.73478  1.000 25.31573  ? 11  ALA A HB2  1 
ATOM   184  H HB3  . ALA A 1 19  ? -6.85981  1.25805   21.61411  1.000 25.31573  ? 11  ALA A HB3  1 
ATOM   185  N N    . ASP A 1 20  ? -6.01125  -2.03233  23.51403  1.000 12.81376  ? 12  ASP A N    1 
ATOM   186  C CA   . ASP A 1 20  ? -5.44263  -3.32074  23.10396  1.000 9.44923   ? 12  ASP A CA   1 
ATOM   187  C C    . ASP A 1 20  ? -3.91917  -3.29375  23.14267  1.000 11.76606  ? 12  ASP A C    1 
ATOM   188  O O    . ASP A 1 20  ? -3.25643  -4.07729  22.46780  1.000 11.66867  ? 12  ASP A O    1 
ATOM   189  C CB   . ASP A 1 20  ? -5.97004  -3.73715  21.72858  1.000 13.59558  ? 12  ASP A CB   1 
ATOM   190  C CG   . ASP A 1 20  ? -7.47454  -4.02405  21.75279  1.000 19.19098  ? 12  ASP A CG   1 
ATOM   191  O OD1  . ASP A 1 20  ? -7.96435  -4.51618  22.78691  1.000 16.90218  ? 12  ASP A OD1  1 
ATOM   192  O OD2  . ASP A 1 20  ? -8.16582  -3.75102  20.74911  1.000 19.56642  ? 12  ASP A OD2  1 
ATOM   193  H H    . ASP A 1 20  ? -6.50865  -2.09412  24.21286  1.000 15.39353  ? 12  ASP A H    1 
ATOM   194  H HA   . ASP A 1 20  ? -5.72039  -4.00457  23.73334  1.000 11.35610  ? 12  ASP A HA   1 
ATOM   195  H HB2  . ASP A 1 20  ? -5.80834  -3.02085  21.09481  1.000 16.33172  ? 12  ASP A HB2  1 
ATOM   196  H HB3  . ASP A 1 20  ? -5.51246  -4.54308  21.44222  1.000 16.33172  ? 12  ASP A HB3  1 
ATOM   197  N N    . VAL A 1 21  ? -3.36586  -2.42627  23.99075  1.000 9.77739   ? 13  VAL A N    1 
ATOM   198  C CA   . VAL A 1 21  ? -1.92810  -2.32468  24.20521  1.000 11.26196  ? 13  VAL A CA   1 
ATOM   199  C C    . VAL A 1 21  ? -1.70474  -2.39582  25.70892  1.000 12.38771  ? 13  VAL A C    1 
ATOM   200  O O    . VAL A 1 21  ? -1.20875  -3.40339  26.23408  1.000 10.67884  ? 13  VAL A O    1 
ATOM   201  C CB   . VAL A 1 21  ? -1.35072  -1.03107  23.60869  1.000 8.97780   ? 13  VAL A CB   1 
ATOM   202  C CG1  . VAL A 1 21  ? 0.15876   -0.94315  23.90679  1.000 11.50348  ? 13  VAL A CG1  1 
ATOM   203  C CG2  . VAL A 1 21  ? -1.58304  -0.99926  22.08898  1.000 13.02039  ? 13  VAL A CG2  1 
ATOM   204  H H    . VAL A 1 21  ? -3.81785  -1.87043  24.46651  1.000 11.74988  ? 13  VAL A H    1 
ATOM   205  H HA   . VAL A 1 21  ? -1.46826  -3.05871  23.76859  1.000 13.53137  ? 13  VAL A HA   1 
ATOM   206  H HB   . VAL A 1 21  ? -1.79680  -0.26848  24.00915  1.000 10.79038  ? 13  VAL A HB   1 
ATOM   207  H HG11 . VAL A 1 21  ? 0.52540   -0.16753  23.45415  1.000 13.82119  ? 13  VAL A HG11 1 
ATOM   208  H HG12 . VAL A 1 21  ? 0.28712   -0.85856  24.86454  1.000 13.82119  ? 13  VAL A HG12 1 
ATOM   209  H HG13 . VAL A 1 21  ? 0.59170   -1.74930  23.58496  1.000 13.82119  ? 13  VAL A HG13 1 
ATOM   210  H HG21 . VAL A 1 21  ? -1.20579  -0.18138  21.72890  1.000 15.64149  ? 13  VAL A HG21 1 
ATOM   211  H HG22 . VAL A 1 21  ? -1.14966  -1.76839  21.68709  1.000 15.64149  ? 13  VAL A HG22 1 
ATOM   212  H HG23 . VAL A 1 21  ? -2.53679  -1.02840  21.91464  1.000 15.64149  ? 13  VAL A HG23 1 
ATOM   213  N N    . VAL A 1 22  ? -2.09551  -1.33313  26.41284  1.000 11.60355  ? 14  VAL A N    1 
ATOM   214  C CA   . VAL A 1 22  ? -1.98389  -1.31169  27.86833  1.000 11.25532  ? 14  VAL A CA   1 
ATOM   215  C C    . VAL A 1 22  ? -3.19026  -1.97966  28.51831  1.000 14.78630  ? 14  VAL A C    1 
ATOM   216  O O    . VAL A 1 22  ? -3.05546  -2.66051  29.53902  1.000 14.64458  ? 14  VAL A O    1 
ATOM   217  C CB   . VAL A 1 22  ? -1.79940  0.13671   28.36177  1.000 11.15128  ? 14  VAL A CB   1 
ATOM   218  C CG1  . VAL A 1 22  ? -1.81437  0.20585   29.88160  1.000 14.75268  ? 14  VAL A CG1  1 
ATOM   219  C CG2  . VAL A 1 22  ? -0.51991  0.69670   27.80513  1.000 13.70657  ? 14  VAL A CG2  1 
ATOM   220  H H    . VAL A 1 22  ? -2.42680  -0.61594  26.07301  1.000 13.94129  ? 14  VAL A H    1 
ATOM   221  H HA   . VAL A 1 22  ? -1.19724  -1.81887  28.12299  1.000 13.52341  ? 14  VAL A HA   1 
ATOM   222  H HB   . VAL A 1 22  ? -2.53942  0.67921   28.04718  1.000 13.39856  ? 14  VAL A HB   1 
ATOM   223  H HG11 . VAL A 1 22  ? -1.52934  1.09014   30.16032  1.000 17.72024  ? 14  VAL A HG11 1 
ATOM   224  H HG12 . VAL A 1 22  ? -2.71557  0.03417   30.19667  1.000 17.72024  ? 14  VAL A HG12 1 
ATOM   225  H HG13 . VAL A 1 22  ? -1.20752  -0.46373  30.23418  1.000 17.72024  ? 14  VAL A HG13 1 
ATOM   226  H HG21 . VAL A 1 22  ? -0.36570  1.57399   28.18917  1.000 16.46491  ? 14  VAL A HG21 1 
ATOM   227  H HG22 . VAL A 1 22  ? 0.21127   0.10201   28.03453  1.000 16.46491  ? 14  VAL A HG22 1 
ATOM   228  H HG23 . VAL A 1 22  ? -0.59905  0.76698   26.84092  1.000 16.46491  ? 14  VAL A HG23 1 
ATOM   229  N N    . LEU A 1 23  ? -4.37839  -1.77777  27.95018  1.000 14.14565  ? 15  LEU A N    1 
ATOM   230  C CA   . LEU A 1 23  ? -5.61422  -2.38467  28.42410  1.000 13.05869  ? 15  LEU A CA   1 
ATOM   231  C C    . LEU A 1 23  ? -6.33400  -3.08154  27.27504  1.000 15.67956  ? 15  LEU A C    1 
ATOM   232  O O    . LEU A 1 23  ? -6.50048  -2.49083  26.19174  1.000 16.66049  ? 15  LEU A O    1 
ATOM   233  C CB   . LEU A 1 23  ? -6.53556  -1.32793  29.04353  1.000 15.92444  ? 15  LEU A CB   1 
ATOM   234  C CG   . LEU A 1 23  ? -6.05769  -0.67507  30.33783  1.000 14.50394  ? 15  LEU A CG   1 
ATOM   235  C CD1  . LEU A 1 23  ? -7.03809  0.46606   30.71660  1.000 19.78545  ? 15  LEU A CD1  1 
ATOM   236  C CD2  . LEU A 1 23  ? -5.92855  -1.66733  31.46714  1.000 17.78741  ? 15  LEU A CD2  1 
ATOM   237  H H    . LEU A 1 23  ? -4.49558  -1.27384  27.26321  1.000 16.99180  ? 15  LEU A H    1 
ATOM   238  H HA   . LEU A 1 23  ? -5.39072  -3.05225  29.09140  1.000 15.68745  ? 15  LEU A HA   1 
ATOM   239  H HB2  . LEU A 1 23  ? -6.65546  -0.61732  28.39426  1.000 19.12635  ? 15  LEU A HB2  1 
ATOM   240  H HB3  . LEU A 1 23  ? -7.38797  -1.74913  29.23560  1.000 19.12635  ? 15  LEU A HB3  1 
ATOM   241  H HG   . LEU A 1 23  ? -5.16977  -0.31053  30.19783  1.000 17.42175  ? 15  LEU A HG   1 
ATOM   242  H HD11 . LEU A 1 23  ? -6.73357  0.88475   31.53689  1.000 23.75956  ? 15  LEU A HD11 1 
ATOM   243  H HD12 . LEU A 1 23  ? -7.05570  1.11846   29.99899  1.000 23.75956  ? 15  LEU A HD12 1 
ATOM   244  H HD13 . LEU A 1 23  ? -7.92370  0.09183   30.84524  1.000 23.75956  ? 15  LEU A HD13 1 
ATOM   245  H HD21 . LEU A 1 23  ? -5.68226  -1.19373  32.27704  1.000 21.36192  ? 15  LEU A HD21 1 
ATOM   246  H HD22 . LEU A 1 23  ? -6.77940  -2.11604  31.59212  1.000 21.36192  ? 15  LEU A HD22 1 
ATOM   247  H HD23 . LEU A 1 23  ? -5.24291  -2.31527  31.24136  1.000 21.36192  ? 15  LEU A HD23 1 
ATOM   248  N N    . PRO A 1 24  ? -6.79275  -4.31621  27.46482  1.000 14.92580  ? 16  PRO A N    1 
ATOM   249  C CA   . PRO A 1 24  ? -7.59530  -4.96280  26.41473  1.000 19.16960  ? 16  PRO A CA   1 
ATOM   250  C C    . PRO A 1 24  ? -8.98975  -4.35968  26.37602  1.000 23.87467  ? 16  PRO A C    1 
ATOM   251  O O    . PRO A 1 24  ? -9.69967  -4.34564  27.38352  1.000 26.86121  ? 16  PRO A O    1 
ATOM   252  C CB   . PRO A 1 24  ? -7.61813  -6.43609  26.83111  1.000 18.33622  ? 16  PRO A CB   1 
ATOM   253  C CG   . PRO A 1 24  ? -7.36705  -6.43217  28.29826  1.000 17.51203  ? 16  PRO A CG   1 
ATOM   254  C CD   . PRO A 1 24  ? -6.55787  -5.19091  28.62628  1.000 13.20144  ? 16  PRO A CD   1 
ATOM   255  H HA   . PRO A 1 24  ? -7.17129  -4.88024  25.54622  1.000 23.02055  ? 16  PRO A HA   1 
ATOM   256  H HB2  . PRO A 1 24  ? -8.48495  -6.82178  26.62922  1.000 22.02049  ? 16  PRO A HB2  1 
ATOM   257  H HB3  . PRO A 1 24  ? -6.92161  -6.92154  26.36195  1.000 22.02049  ? 16  PRO A HB3  1 
ATOM   258  H HG2  . PRO A 1 24  ? -8.21586  -6.41418  28.76741  1.000 21.03145  ? 16  PRO A HG2  1 
ATOM   259  H HG3  . PRO A 1 24  ? -6.87149  -7.23036  28.53952  1.000 21.03145  ? 16  PRO A HG3  1 
ATOM   260  H HD2  . PRO A 1 24  ? -6.87872  -4.77528  29.44188  1.000 15.85875  ? 16  PRO A HD2  1 
ATOM   261  H HD3  . PRO A 1 24  ? -5.61580  -5.40563  28.71175  1.000 15.85875  ? 16  PRO A HD3  1 
ATOM   262  N N    . LEU A 1 25  ? -9.37600  -3.85058  25.20959  1.000 19.76592  ? 17  LEU A N    1 
ATOM   263  C CA   . LEU A 1 25  ? -10.64419 -3.14671  25.05296  1.000 25.52254  ? 17  LEU A CA   1 
ATOM   264  C C    . LEU A 1 25  ? -11.59387 -3.85688  24.10158  1.000 38.85636  ? 17  LEU A C    1 
ATOM   265  O O    . LEU A 1 25  ? -12.75185 -4.10028  24.45855  1.000 39.23956  ? 17  LEU A O    1 
ATOM   266  C CB   . LEU A 1 25  ? -10.39877 -1.71032  24.55603  1.000 31.95105  ? 17  LEU A CB   1 
ATOM   267  C CG   . LEU A 1 25  ? -9.68524  -0.74585  25.50502  1.000 38.52134  ? 17  LEU A CG   1 
ATOM   268  C CD1  . LEU A 1 25  ? -9.75875  0.68200   24.93212  1.000 56.88004  ? 17  LEU A CD1  1 
ATOM   269  C CD2  . LEU A 1 25  ? -10.24287 -0.77516  26.90693  1.000 46.50267  ? 17  LEU A CD2  1 
ATOM   270  H H    . LEU A 1 25  ? -8.91462  -3.90090  24.48558  1.000 23.73612  ? 17  LEU A H    1 
ATOM   271  H HA   . LEU A 1 25  ? -11.07186 -3.09684  25.92215  1.000 30.64407  ? 17  LEU A HA   1 
ATOM   272  H HB2  . LEU A 1 25  ? -9.85909  -1.76316  23.75176  1.000 38.35829  ? 17  LEU A HB2  1 
ATOM   273  H HB3  . LEU A 1 25  ? -11.26114 -1.31609  24.35159  1.000 38.35829  ? 17  LEU A HB3  1 
ATOM   274  H HG   . LEU A 1 25  ? -8.75994  -1.02774  25.57754  1.000 46.24263  ? 17  LEU A HG   1 
ATOM   275  H HD11 . LEU A 1 25  ? -9.29220  1.28663   25.53016  1.000 68.27307  ? 17  LEU A HD11 1 
ATOM   276  H HD12 . LEU A 1 25  ? -9.33975  0.69325   24.05736  1.000 68.27307  ? 17  LEU A HD12 1 
ATOM   277  H HD13 . LEU A 1 25  ? -10.68952 0.94438   24.85646  1.000 68.27307  ? 17  LEU A HD13 1 
ATOM   278  H HD21 . LEU A 1 25  ? -9.78209  -0.11174  27.44402  1.000 55.82022  ? 17  LEU A HD21 1 
ATOM   279  H HD22 . LEU A 1 25  ? -11.19109 -0.57346  26.87391  1.000 55.82022  ? 17  LEU A HD22 1 
ATOM   280  H HD23 . LEU A 1 25  ? -10.10553 -1.65867  27.28302  1.000 55.82022  ? 17  LEU A HD23 1 
ATOM   281  N N    . THR A 1 26  ? -11.13033 -4.20007  22.89842  1.000 28.46805  ? 18  THR A N    1 
ATOM   282  C CA   . THR A 1 26  ? -11.97881 -4.85332  21.90990  1.000 36.33887  ? 18  THR A CA   1 
ATOM   283  C C    . THR A 1 26  ? -12.66365 -6.07364  22.49946  1.000 40.10060  ? 18  THR A C    1 
ATOM   284  O O    . THR A 1 26  ? -13.88355 -6.23511  22.39644  1.000 33.23188  ? 18  THR A O    1 
ATOM   285  C CB   . THR A 1 26  ? -11.13159 -5.24711  20.69454  1.000 26.24689  ? 18  THR A CB   1 
ATOM   286  O OG1  . THR A 1 26  ? -10.61755 -4.05913  20.08517  1.000 24.68730  ? 18  THR A OG1  1 
ATOM   287  C CG2  . THR A 1 26  ? -11.95001 -6.02357  19.67668  1.000 29.03902  ? 18  THR A CG2  1 
ATOM   288  H H    . THR A 1 26  ? -10.32442 -4.06418  22.63074  1.000 34.17868  ? 18  THR A H    1 
ATOM   289  H HA   . THR A 1 26  ? -12.66691 -4.23427  21.61971  1.000 43.62367  ? 18  THR A HA   1 
ATOM   290  H HB   . THR A 1 26  ? -10.40271 -5.81953  20.98083  1.000 31.51330  ? 18  THR A HB   1 
ATOM   291  H HG1  . THR A 1 26  ? -10.27443 -4.24338  19.34091  1.000 29.64178  ? 18  THR A HG1  1 
ATOM   292  H HG21 . THR A 1 26  ? -11.41961 -6.18972  18.88171  1.000 34.86385  ? 18  THR A HG21 1 
ATOM   293  H HG22 . THR A 1 26  ? -12.22783 -6.87332  20.05303  1.000 34.86385  ? 18  THR A HG22 1 
ATOM   294  H HG23 . THR A 1 26  ? -12.73867 -5.51626  19.42856  1.000 34.86385  ? 18  THR A HG23 1 
ATOM   295  N N    . SER A 1 27  ? -11.88096 -6.95267  23.10903  1.000 32.89743  ? 19  SER A N    1 
ATOM   296  C CA   . SER A 1 27  ? -12.35138 -8.20063  23.67863  1.000 38.59005  ? 19  SER A CA   1 
ATOM   297  C C    . SER A 1 27  ? -12.40077 -8.08404  25.19830  1.000 48.68796  ? 19  SER A C    1 
ATOM   298  O O    . SER A 1 27  ? -11.63987 -7.33395  25.80833  1.000 42.55579  ? 19  SER A O    1 
ATOM   299  C CB   . SER A 1 27  ? -11.42577 -9.34290  23.24944  1.000 45.34454  ? 19  SER A CB   1 
ATOM   300  O OG   . SER A 1 27  ? -11.60044 -10.49107 24.05794  1.000 60.25309  ? 19  SER A OG   1 
ATOM   301  H H    . SER A 1 27  ? -11.03406 -6.84114  23.20864  1.000 39.49394  ? 19  SER A H    1 
ATOM   302  H HA   . SER A 1 27  ? -13.24782 -8.40677  23.37073  1.000 46.32508  ? 19  SER A HA   1 
ATOM   303  H HB2  . SER A 1 27  ? -11.62393 -9.57617  22.32899  1.000 54.43047  ? 19  SER A HB2  1 
ATOM   304  H HB3  . SER A 1 27  ? -10.50591 -9.04461  23.32543  1.000 54.43047  ? 19  SER A HB3  1 
ATOM   305  H HG   . SER A 1 27  ? -11.01938 -11.06721 23.86812  1.000 72.32073  ? 19  SER A HG   1 
ATOM   306  N N    . ASN A 1 28  ? -13.33277 -8.79806  25.81142  1.000 61.36262  ? 20  ASN A N    1 
ATOM   307  C CA   . ASN A 1 28  ? -13.29023 -8.98236  27.25911  1.000 71.64320  ? 20  ASN A CA   1 
ATOM   308  C C    . ASN A 1 28  ? -13.39939 -10.46928 27.59176  1.000 54.91001  ? 20  ASN A C    1 
ATOM   309  O O    . ASN A 1 28  ? -13.95474 -10.84890 28.62312  1.000 70.58750  ? 20  ASN A O    1 
ATOM   310  C CB   . ASN A 1 28  ? -14.36934 -8.15784  27.97377  1.000 60.87208  ? 20  ASN A CB   1 
ATOM   311  C CG   . ASN A 1 28  ? -15.75425 -8.38620  27.43119  1.000 78.00668  ? 20  ASN A CG   1 
ATOM   312  O OD1  . ASN A 1 28  ? -16.12110 -9.50142  27.07477  1.000 84.33082  ? 20  ASN A OD1  1 
ATOM   313  N ND2  . ASN A 1 28  ? -16.54889 -7.32411  27.39305  1.000 79.72996  ? 20  ASN A ND2  1 
ATOM   314  H H    . ASN A 1 28  ? -13.99354 -9.18250  25.41748  1.000 73.65216  ? 20  ASN A H    1 
ATOM   315  H HA   . ASN A 1 28  ? -12.44195 -8.65718  27.59907  1.000 85.98887  ? 20  ASN A HA   1 
ATOM   316  H HB2  . ASN A 1 28  ? -14.37540 -8.39707  28.91379  1.000 73.06352  ? 20  ASN A HB2  1 
ATOM   317  H HB3  . ASN A 1 28  ? -14.16227 -7.21562  27.87255  1.000 73.06352  ? 20  ASN A HB3  1 
ATOM   318  H HD21 . ASN A 1 28  ? -16.26163 -6.56201  27.66925  1.000 95.69298  ? 20  ASN A HD21 1 
ATOM   319  H HD22 . ASN A 1 28  ? -17.35114 -7.39790  27.09213  1.000 95.69298  ? 20  ASN A HD22 1 
ATOM   320  N N    . THR A 1 29  ? -12.84951 -11.30754 26.70874  1.000 59.71034  ? 21  THR A N    1 
ATOM   321  C CA   . THR A 1 29  ? -12.90103 -12.76302 26.75832  1.000 57.41383  ? 21  THR A CA   1 
ATOM   322  C C    . THR A 1 29  ? -11.49310 -13.33756 26.66065  1.000 62.23808  ? 21  THR A C    1 
ATOM   323  O O    . THR A 1 29  ? -11.29521 -14.43648 26.13257  1.000 61.43816  ? 21  THR A O    1 
ATOM   324  C CB   . THR A 1 29  ? -13.78125 -13.29177 25.62418  1.000 66.92901  ? 21  THR A CB   1 
ATOM   325  O OG1  . THR A 1 29  ? -13.08967 -13.13137 24.37768  1.000 62.66186  ? 21  THR A OG1  1 
ATOM   326  C CG2  . THR A 1 29  ? -15.09735 -12.51632 25.56220  1.000 72.55703  ? 21  THR A CG2  1 
ATOM   327  H H    . THR A 1 29  ? -12.40962 -11.03266 26.02278  1.000 71.66943  ? 21  THR A H    1 
ATOM   328  H HA   . THR A 1 29  ? -13.28637 -13.05388 27.59964  1.000 68.91362  ? 21  THR A HA   1 
ATOM   329  H HB   . THR A 1 29  ? -13.98066 -14.22880 25.77620  1.000 80.33184  ? 21  THR A HB   1 
ATOM   330  H HG1  . THR A 1 29  ? -13.55578 -13.43680 23.74915  1.000 75.21126  ? 21  THR A HG1  1 
ATOM   331  H HG21 . THR A 1 29  ? -15.63220 -12.82963 24.81610  1.000 87.08546  ? 21  THR A HG21 1 
ATOM   332  H HG22 . THR A 1 29  ? -15.59706 -12.64471 26.38361  1.000 87.08546  ? 21  THR A HG22 1 
ATOM   333  H HG23 . THR A 1 29  ? -14.91958 -11.56979 25.44655  1.000 87.08546  ? 21  THR A HG23 1 
ATOM   334  N N    . GLN A 1 30  ? -10.49827 -12.58527 27.15124  1.000 38.40962  ? 22  GLN A N    1 
ATOM   335  C CA   . GLN A 1 30  ? -9.09085  -12.92536 26.99888  1.000 37.50711  ? 22  GLN A CA   1 
ATOM   336  C C    . GLN A 1 30  ? -8.71475  -14.08024 27.92783  1.000 31.19668  ? 22  GLN A C    1 
ATOM   337  O O    . GLN A 1 30  ? -9.41998  -14.35097 28.90043  1.000 36.65327  ? 22  GLN A O    1 
ATOM   338  C CB   . GLN A 1 30  ? -8.23843  -11.70119 27.32129  1.000 37.05698  ? 22  GLN A CB   1 
ATOM   339  C CG   . GLN A 1 30  ? -8.43946  -10.51559 26.38259  1.000 50.24993  ? 22  GLN A CG   1 
ATOM   340  C CD   . GLN A 1 30  ? -7.51606  -10.59135 25.18387  1.000 33.97126  ? 22  GLN A CD   1 
ATOM   341  O OE1  . GLN A 1 30  ? -6.63611  -11.44595 25.12882  1.000 27.39972  ? 22  GLN A OE1  1 
ATOM   342  N NE2  . GLN A 1 30  ? -7.71833  -9.71113  24.21166  1.000 35.18924  ? 22  GLN A NE2  1 
ATOM   343  H H    . GLN A 1 30  ? -10.62195 -11.85432 27.58714  1.000 46.10857  ? 22  GLN A H    1 
ATOM   344  H HA   . GLN A 1 30  ? -8.91242  -13.20454 26.08722  1.000 45.02556  ? 22  GLN A HA   1 
ATOM   345  H HB2  . GLN A 1 30  ? -8.45536  -11.40286 28.21842  1.000 44.48540  ? 22  GLN A HB2  1 
ATOM   346  H HB3  . GLN A 1 30  ? -7.30369  -11.95588 27.27331  1.000 44.48540  ? 22  GLN A HB3  1 
ATOM   347  H HG2  . GLN A 1 30  ? -9.35509  -10.51177 26.06242  1.000 60.31693  ? 22  GLN A HG2  1 
ATOM   348  H HG3  . GLN A 1 30  ? -8.25171  -9.69271  26.86061  1.000 60.31693  ? 22  GLN A HG3  1 
ATOM   349  H HE21 . GLN A 1 30  ? -8.35101  -9.13265  24.28012  1.000 42.24411  ? 22  GLN A HE21 1 
ATOM   350  H HE22 . GLN A 1 30  ? -7.21674  -9.71914  23.51313  1.000 42.24411  ? 22  GLN A HE22 1 
ATOM   351  N N    . PRO A 1 31  ? -7.61671  -14.79121 27.64634  1.000 24.88040  ? 23  PRO A N    1 
ATOM   352  C CA   . PRO A 1 31  ? -7.12049  -15.75775 28.64168  1.000 21.92969  ? 23  PRO A CA   1 
ATOM   353  C C    . PRO A 1 31  ? -6.92282  -15.07601 29.98587  1.000 24.96801  ? 23  PRO A C    1 
ATOM   354  O O    . PRO A 1 31  ? -6.35535  -13.98325 30.07705  1.000 28.95728  ? 23  PRO A O    1 
ATOM   355  C CB   . PRO A 1 31  ? -5.79932  -16.25421 28.04613  1.000 31.04493  ? 23  PRO A CB   1 
ATOM   356  C CG   . PRO A 1 31  ? -6.00964  -16.12728 26.57141  1.000 30.88545  ? 23  PRO A CG   1 
ATOM   357  C CD   . PRO A 1 31  ? -6.88264  -14.89014 26.37224  1.000 31.46406  ? 23  PRO A CD   1 
ATOM   358  H HA   . PRO A 1 31  ? -7.72618  -16.50991 28.73272  1.000 26.33265  ? 23  PRO A HA   1 
ATOM   359  H HB2  . PRO A 1 31  ? -5.06480  -15.69642 28.34655  1.000 37.27094  ? 23  PRO A HB2  1 
ATOM   360  H HB3  . PRO A 1 31  ? -5.64138  -17.17660 28.30138  1.000 37.27094  ? 23  PRO A HB3  1 
ATOM   361  H HG2  . PRO A 1 31  ? -5.15378  -16.01748 26.12829  1.000 37.07956  ? 23  PRO A HG2  1 
ATOM   362  H HG3  . PRO A 1 31  ? -6.45734  -16.91994 26.23653  1.000 37.07956  ? 23  PRO A HG3  1 
ATOM   363  H HD2  . PRO A 1 31  ? -6.33710  -14.10171 26.22506  1.000 37.77389  ? 23  PRO A HD2  1 
ATOM   364  H HD3  . PRO A 1 31  ? -7.49397  -15.01398 25.62938  1.000 37.77389  ? 23  PRO A HD3  1 
ATOM   365  N N    . GLN A 1 32  ? -7.40019  -15.73537 31.04270  1.000 33.58601  ? 24  GLN A N    1 
ATOM   366  C CA   . GLN A 1 32  ? -7.45371  -15.10115 32.35520  1.000 28.17241  ? 24  GLN A CA   1 
ATOM   367  C C    . GLN A 1 32  ? -6.07384  -14.74139 32.89899  1.000 34.58922  ? 24  GLN A C    1 
ATOM   368  O O    . GLN A 1 32  ? -5.96596  -13.82615 33.71795  1.000 28.30402  ? 24  GLN A O    1 
ATOM   369  C CB   . GLN A 1 32  ? -8.19123  -16.02521 33.33455  1.000 25.18254  ? 24  GLN A CB   1 
ATOM   370  C CG   . GLN A 1 32  ? -9.64084  -16.27365 32.95908  1.000 41.86273  ? 24  GLN A CG   1 
ATOM   371  C CD   . GLN A 1 32  ? -10.56712 -16.31628 34.15648  1.000 37.05991  ? 24  GLN A CD   1 
ATOM   372  O OE1  . GLN A 1 32  ? -10.94523 -17.39181 34.62024  1.000 29.72271  ? 24  GLN A OE1  1 
ATOM   373  N NE2  . GLN A 1 32  ? -10.94157 -15.14194 34.66352  1.000 37.23938  ? 24  GLN A NE2  1 
ATOM   374  H H    . GLN A 1 32  ? -7.69593  -16.54272 31.02488  1.000 40.32024  ? 24  GLN A H    1 
ATOM   375  H HA   . GLN A 1 32  ? -7.95038  -14.27114 32.28239  1.000 33.82391  ? 24  GLN A HA   1 
ATOM   376  H HB2  . GLN A 1 32  ? -7.73876  -16.88294 33.35603  1.000 30.23607  ? 24  GLN A HB2  1 
ATOM   377  H HB3  . GLN A 1 32  ? -8.17785  -15.62088 34.21617  1.000 30.23607  ? 24  GLN A HB3  1 
ATOM   378  H HG2  . GLN A 1 32  ? -9.94125  -15.55996 32.37486  1.000 50.25230  ? 24  GLN A HG2  1 
ATOM   379  H HG3  . GLN A 1 32  ? -9.70556  -17.12644 32.50141  1.000 50.25230  ? 24  GLN A HG3  1 
ATOM   380  H HE21 . GLN A 1 32  ? -10.65771 -14.41095 34.31042  1.000 44.70428  ? 24  GLN A HE21 1 
ATOM   381  H HE22 . GLN A 1 32  ? -11.46704 -15.11519 35.34379  1.000 44.70428  ? 24  GLN A HE22 1 
ATOM   382  N N    . GLU A 1 33  ? -5.02261  -15.42506 32.46505  1.000 22.72992  ? 25  GLU A N    1 
ATOM   383  C CA   . GLU A 1 33  ? -3.66566  -15.17436 32.94092  1.000 18.98652  ? 25  GLU A CA   1 
ATOM   384  C C    . GLU A 1 33  ? -2.90555  -14.15637 32.08985  1.000 13.91407  ? 25  GLU A C    1 
ATOM   385  O O    . GLU A 1 33  ? -1.84856  -13.66727 32.51081  1.000 14.46872  ? 25  GLU A O    1 
ATOM   386  C CB   . GLU A 1 33  ? -2.89009  -16.50163 32.97527  1.000 16.73624  ? 25  GLU A CB   1 
ATOM   387  C CG   . GLU A 1 33  ? -2.53739  -17.08130 31.61967  1.000 21.99026  ? 25  GLU A CG   1 
ATOM   388  C CD   . GLU A 1 33  ? -3.48334  -18.18940 31.16321  1.000 28.53425  ? 25  GLU A CD   1 
ATOM   389  O OE1  . GLU A 1 33  ? -4.68316  -17.90295 30.97386  1.000 21.65878  ? 25  GLU A OE1  1 
ATOM   390  O OE2  . GLU A 1 33  ? -3.02111  -19.34734 30.98257  1.000 27.62980  ? 25  GLU A OE2  1 
ATOM   391  H H    . GLU A 1 33  ? -5.06867  -16.05469 31.88106  1.000 27.29293  ? 25  GLU A H    1 
ATOM   392  H HA   . GLU A 1 33  ? -3.70448  -14.81837 33.84240  1.000 22.80085  ? 25  GLU A HA   1 
ATOM   393  H HB2  . GLU A 1 33  ? -2.05870  -16.35768 33.45378  1.000 20.10051  ? 25  GLU A HB2  1 
ATOM   394  H HB3  . GLU A 1 33  ? -3.43057  -17.15967 33.43979  1.000 20.10051  ? 25  GLU A HB3  1 
ATOM   395  H HG2  . GLU A 1 33  ? -2.57035  -16.37253 30.95827  1.000 26.40533  ? 25  GLU A HG2  1 
ATOM   396  H HG3  . GLU A 1 33  ? -1.64292  -17.45417 31.66208  1.000 26.40533  ? 25  GLU A HG3  1 
ATOM   397  N N    . LEU A 1 34  ? -3.44253  -13.79478 30.92859  1.000 12.33207  ? 26  LEU A N    1 
ATOM   398  C CA   . LEU A 1 34  ? -2.69157  -12.99118 29.97362  1.000 12.78391  ? 26  LEU A CA   1 
ATOM   399  C C    . LEU A 1 34  ? -2.51211  -11.55369 30.44947  1.000 13.17732  ? 26  LEU A C    1 
ATOM   400  O O    . LEU A 1 34  ? -1.41409  -10.99677 30.35585  1.000 11.90362  ? 26  LEU A O    1 
ATOM   401  C CB   . LEU A 1 34  ? -3.39637  -13.01195 28.62262  1.000 14.71506  ? 26  LEU A CB   1 
ATOM   402  C CG   . LEU A 1 34  ? -2.73199  -12.19282 27.50923  1.000 15.46263  ? 26  LEU A CG   1 
ATOM   403  C CD1  . LEU A 1 34  ? -1.31789  -12.70164 27.23122  1.000 17.25108  ? 26  LEU A CD1  1 
ATOM   404  C CD2  . LEU A 1 34  ? -3.61138  -12.26424 26.26225  1.000 18.66699  ? 26  LEU A CD2  1 
ATOM   405  H H    . LEU A 1 34  ? -4.23663  -14.00098 30.67074  1.000 14.81551  ? 26  LEU A H    1 
ATOM   406  H HA   . LEU A 1 34  ? -1.80849  -13.38081 29.87741  1.000 15.35771  ? 26  LEU A HA   1 
ATOM   407  H HB2  . LEU A 1 34  ? -3.43887  -13.93161 28.31715  1.000 17.67509  ? 26  LEU A HB2  1 
ATOM   408  H HB3  . LEU A 1 34  ? -4.29245  -12.66058 28.74291  1.000 17.67509  ? 26  LEU A HB3  1 
ATOM   409  H HG   . LEU A 1 34  ? -2.64308  -11.26466 27.77665  1.000 18.57218  ? 26  LEU A HG   1 
ATOM   410  H HD11 . LEU A 1 34  ? -0.94453  -12.20544 26.48604  1.000 20.71832  ? 26  LEU A HD11 1 
ATOM   411  H HD12 . LEU A 1 34  ? -0.77326  -12.56915 28.02289  1.000 20.71832  ? 26  LEU A HD12 1 
ATOM   412  H HD13 . LEU A 1 34  ? -1.35928  -13.64573 27.01240  1.000 20.71832  ? 26  LEU A HD13 1 
ATOM   413  H HD21 . LEU A 1 34  ? -3.22719  -11.70109 25.57221  1.000 22.41741  ? 26  LEU A HD21 1 
ATOM   414  H HD22 . LEU A 1 34  ? -3.65011  -13.18360 25.95537  1.000 22.41741  ? 26  LEU A HD22 1 
ATOM   415  H HD23 . LEU A 1 34  ? -4.50225  -11.95233 26.48579  1.000 22.41741  ? 26  LEU A HD23 1 
ATOM   416  N N    . LYS A 1 35  ? -3.58410  -10.91389 30.91528  1.000 11.75214  ? 27  LYS A N    1 
ATOM   417  C CA   . LYS A 1 35  ? -3.46998  -9.50352  31.28125  1.000 13.14284  ? 27  LYS A CA   1 
ATOM   418  C C    . LYS A 1 35  ? -2.41110  -9.29485  32.35462  1.000 15.11368  ? 27  LYS A C    1 
ATOM   419  O O    . LYS A 1 35  ? -1.62839  -8.34237  32.28090  1.000 12.69578  ? 27  LYS A O    1 
ATOM   420  C CB   . LYS A 1 35  ? -4.82083  -8.97234  31.75471  1.000 12.99173  ? 27  LYS A CB   1 
ATOM   421  C CG   . LYS A 1 35  ? -4.95234  -7.46995  31.70627  1.000 36.03643  ? 27  LYS A CG   1 
ATOM   422  C CD   . LYS A 1 35  ? -4.68389  -6.85353  33.06343  1.000 38.32368  ? 27  LYS A CD   1 
ATOM   423  C CE   . LYS A 1 35  ? -4.77211  -5.32783  32.99699  1.000 27.90378  ? 27  LYS A CE   1 
ATOM   424  N NZ   . LYS A 1 35  ? -4.63234  -4.75305  34.35711  1.000 26.20394  ? 27  LYS A NZ   1 
ATOM   425  H H    . LYS A 1 35  ? -4.36315  -11.26106 31.02554  1.000 14.11959  ? 27  LYS A H    1 
ATOM   426  H HA   . LYS A 1 35  ? -3.20631  -8.99948  30.49555  1.000 15.78843  ? 27  LYS A HA   1 
ATOM   427  H HB2  . LYS A 1 35  ? -5.51520  -9.34588  31.18970  1.000 15.60710  ? 27  LYS A HB2  1 
ATOM   428  H HB3  . LYS A 1 35  ? -4.95680  -9.24914  32.67438  1.000 15.60710  ? 27  LYS A HB3  1 
ATOM   429  H HG2  . LYS A 1 35  ? -4.31059  -7.11017  31.07413  1.000 43.26073  ? 27  LYS A HG2  1 
ATOM   430  H HG3  . LYS A 1 35  ? -5.85323  -7.23356  31.43531  1.000 43.26073  ? 27  LYS A HG3  1 
ATOM   431  H HD2  . LYS A 1 35  ? -5.34316  -7.17211  33.69965  1.000 46.00544  ? 27  LYS A HD2  1 
ATOM   432  H HD3  . LYS A 1 35  ? -3.79275  -7.09730  33.35899  1.000 46.00544  ? 27  LYS A HD3  1 
ATOM   433  H HE2  . LYS A 1 35  ? -4.05813  -4.98302  32.43821  1.000 33.50155  ? 27  LYS A HE2  1 
ATOM   434  H HE3  . LYS A 1 35  ? -5.63291  -5.06551  32.63489  1.000 33.50155  ? 27  LYS A HE3  1 
ATOM   435  H HZ1  . LYS A 1 35  ? -4.35718  -3.90833  34.30380  1.000 31.46175  ? 27  LYS A HZ1  1 
ATOM   436  H HZ2  . LYS A 1 35  ? -5.41563  -4.77559  34.77907  1.000 31.46175  ? 27  LYS A HZ2  1 
ATOM   437  H HZ3  . LYS A 1 35  ? -4.03815  -5.22134  34.82589  1.000 31.46175  ? 27  LYS A HZ3  1 
ATOM   438  N N    . SER A 1 36  ? -2.33819  -10.19697 33.33866  1.000 12.79859  ? 28  SER A N    1 
ATOM   439  C CA   . SER A 1 36  ? -1.32391  -10.05863 34.38120  1.000 11.36604  ? 28  SER A CA   1 
ATOM   440  C C    . SER A 1 36  ? 0.07338   -10.26010 33.81441  1.000 14.39690  ? 28  SER A C    1 
ATOM   441  O O    . SER A 1 36  ? 1.01084   -9.54188  34.18526  1.000 14.74202  ? 28  SER A O    1 
ATOM   442  C CB   . SER A 1 36  ? -1.58049  -11.05526 35.51193  1.000 15.79994  ? 28  SER A CB   1 
ATOM   443  O OG   . SER A 1 36  ? -0.73149  -10.80169 36.61363  1.000 15.19212  ? 28  SER A OG   1 
ATOM   444  H H    . SER A 1 36  ? -2.85249  -10.88117 33.42209  1.000 15.37533  ? 28  SER A H    1 
ATOM   445  H HA   . SER A 1 36  ? -1.38285  -9.16365  34.75058  1.000 13.65627  ? 28  SER A HA   1 
ATOM   446  H HB2  . SER A 1 36  ? -2.50317  -10.97425 35.80000  1.000 18.97696  ? 28  SER A HB2  1 
ATOM   447  H HB3  . SER A 1 36  ? -1.41265  -11.95290 35.18487  1.000 18.97696  ? 28  SER A HB3  1 
ATOM   448  H HG   . SER A 1 36  ? -1.17172  -10.46247 37.24349  1.000 18.24757  ? 28  SER A HG   1 
ATOM   449  N N    . ARG A 1 37  ? 0.23337   -11.23190 32.91487  1.000 12.26660  ? 29  ARG A N    1 
ATOM   450  C CA   . ARG A 1 37  ? 1.52831   -11.42792 32.27069  1.000 8.99085   ? 29  ARG A CA   1 
ATOM   451  C C    . ARG A 1 37  ? 1.94292   -10.18665 31.48876  1.000 13.49404  ? 29  ARG A C    1 
ATOM   452  O O    . ARG A 1 37  ? 3.10360   -9.75847  31.53151  1.000 14.10019  ? 29  ARG A O    1 
ATOM   453  C CB   . ARG A 1 37  ? 1.46971   -12.61937 31.31875  1.000 10.98437  ? 29  ARG A CB   1 
ATOM   454  C CG   . ARG A 1 37  ? 1.42251   -13.97899 31.97440  1.000 26.05282  ? 29  ARG A CG   1 
ATOM   455  C CD   . ARG A 1 37  ? 1.64326   -15.07394 30.91887  1.000 33.19074  ? 29  ARG A CD   1 
ATOM   456  N NE   . ARG A 1 37  ? 1.47755   -16.41988 31.46422  1.000 21.86146  ? 29  ARG A NE   1 
ATOM   457  C CZ   . ARG A 1 37  ? 1.51372   -17.53196 30.73854  1.000 26.96968  ? 29  ARG A CZ   1 
ATOM   458  N NH1  . ARG A 1 37  ? 1.72492   -17.45922 29.42552  1.000 30.55716  ? 29  ARG A NH1  1 
ATOM   459  N NH2  . ARG A 1 37  ? 1.35272   -18.71576 31.32966  1.000 22.33664  ? 29  ARG A NH2  1 
ATOM   460  H H    . ARG A 1 37  ? -0.38054  -11.78010 32.66549  1.000 14.73694  ? 29  ARG A H    1 
ATOM   461  H HA   . ARG A 1 37  ? 2.18533   -11.60675 32.96153  1.000 10.80605  ? 29  ARG A HA   1 
ATOM   462  H HB2  . ARG A 1 37  ? 0.67169   -12.53461 30.77389  1.000 13.19826  ? 29  ARG A HB2  1 
ATOM   463  H HB3  . ARG A 1 37  ? 2.25946   -12.59837 30.75595  1.000 13.19826  ? 29  ARG A HB3  1 
ATOM   464  H HG2  . ARG A 1 37  ? 2.12201   -14.04481 32.64318  1.000 31.28041  ? 29  ARG A HG2  1 
ATOM   465  H HG3  . ARG A 1 37  ? 0.55514   -14.11388 32.38715  1.000 31.28041  ? 29  ARG A HG3  1 
ATOM   466  H HD2  . ARG A 1 37  ? 0.99933   -14.95839 30.20269  1.000 39.84591  ? 29  ARG A HD2  1 
ATOM   467  H HD3  . ARG A 1 37  ? 2.54506   -15.00016 30.56928  1.000 39.84591  ? 29  ARG A HD3  1 
ATOM   468  H HE   . ARG A 1 37  ? 1.34807   -16.49694 32.31092  1.000 26.25077  ? 29  ARG A HE   1 
ATOM   469  H HH11 . ARG A 1 37  ? 1.83740   -16.69383 29.04983  1.000 36.68562  ? 29  ARG A HH11 1 
ATOM   470  H HH12 . ARG A 1 37  ? 1.74881   -18.17763 28.95338  1.000 36.68562  ? 29  ARG A HH12 1 
ATOM   471  H HH21 . ARG A 1 37  ? 1.22573   -18.75848 32.17916  1.000 26.82098  ? 29  ARG A HH21 1 
ATOM   472  H HH22 . ARG A 1 37  ? 1.37582   -19.43683 30.86155  1.000 26.82098  ? 29  ARG A HH22 1 
ATOM   473  N N    . ILE A 1 38  ? 1.00481   -9.61761  30.73496  1.000 13.81801  ? 30  ILE A N    1 
ATOM   474  C CA   . ILE A 1 38  ? 1.31628   -8.44234  29.92865  1.000 11.53216  ? 30  ILE A CA   1 
ATOM   475  C C    . ILE A 1 38  ? 1.70055   -7.27149  30.82080  1.000 13.14516  ? 30  ILE A C    1 
ATOM   476  O O    . ILE A 1 38  ? 2.64726   -6.54024  30.51553  1.000 12.53934  ? 30  ILE A O    1 
ATOM   477  C CB   . ILE A 1 38  ? 0.13566   -8.09130  29.00613  1.000 14.59822  ? 30  ILE A CB   1 
ATOM   478  C CG1  . ILE A 1 38  ? -0.06767  -9.19474  27.96551  1.000 13.42659  ? 30  ILE A CG1  1 
ATOM   479  C CG2  . ILE A 1 38  ? 0.35494   -6.74564  28.32069  1.000 12.80917  ? 30  ILE A CG2  1 
ATOM   480  C CD1  . ILE A 1 38  ? 1.14137   -9.39838  27.03787  1.000 12.53983  ? 30  ILE A CD1  1 
ATOM   481  H H    . ILE A 1 38  ? 0.19104   -9.88890  30.67349  1.000 16.59864  ? 30  ILE A H    1 
ATOM   482  H HA   . ILE A 1 38  ? 2.07846   -8.65156  29.36633  1.000 13.85561  ? 30  ILE A HA   1 
ATOM   483  H HB   . ILE A 1 38  ? -0.66269  -8.02370  29.55291  1.000 17.53488  ? 30  ILE A HB   1 
ATOM   484  H HG12 . ILE A 1 38  ? -0.23203  -10.03223 28.42648  1.000 16.12893  ? 30  ILE A HG12 1 
ATOM   485  H HG13 . ILE A 1 38  ? -0.83059  -8.96534  27.41214  1.000 16.12893  ? 30  ILE A HG13 1 
ATOM   486  H HG21 . ILE A 1 38  ? -0.27817  -6.65588  27.59129  1.000 15.38802  ? 30  ILE A HG21 1 
ATOM   487  H HG22 . ILE A 1 38  ? 0.21745   -6.03576  28.96727  1.000 15.38802  ? 30  ILE A HG22 1 
ATOM   488  H HG23 . ILE A 1 38  ? 1.26166   -6.70984  27.97795  1.000 15.38802  ? 30  ILE A HG23 1 
ATOM   489  H HD11 . ILE A 1 38  ? 0.92331   -10.07609 26.37904  1.000 15.06481  ? 30  ILE A HD11 1 
ATOM   490  H HD12 . ILE A 1 38  ? 1.34436   -8.55964  26.59491  1.000 15.06481  ? 30  ILE A HD12 1 
ATOM   491  H HD13 . ILE A 1 38  ? 1.90146   -9.68489  27.56802  1.000 15.06481  ? 30  ILE A HD13 1 
ATOM   492  N N    . ASP A 1 39  ? 0.99007   -7.08360  31.94299  1.000 11.36265  ? 31  ASP A N    1 
ATOM   493  C CA   . ASP A 1 39  ? 1.34684   -6.01444  32.87983  1.000 12.27895  ? 31  ASP A CA   1 
ATOM   494  C C    . ASP A 1 39  ? 2.76140   -6.19563  33.41725  1.000 11.89950  ? 31  ASP A C    1 
ATOM   495  O O    . ASP A 1 39  ? 3.52228   -5.22392  33.55675  1.000 11.59922  ? 31  ASP A O    1 
ATOM   496  C CB   . ASP A 1 39  ? 0.35886   -5.98106  34.04581  1.000 13.91407  ? 31  ASP A CB   1 
ATOM   497  C CG   . ASP A 1 39  ? -0.98283  -5.41428  33.66614  1.000 21.19592  ? 31  ASP A CG   1 
ATOM   498  O OD1  . ASP A 1 39  ? -1.11538  -4.83336  32.56485  1.000 18.47691  ? 31  ASP A OD1  1 
ATOM   499  O OD2  . ASP A 1 39  ? -1.91342  -5.55803  34.49034  1.000 18.22054  ? 31  ASP A OD2  1 
ATOM   500  H H    . ASP A 1 39  ? 0.30979   -7.55368  32.17932  1.000 13.65220  ? 31  ASP A H    1 
ATOM   501  H HA   . ASP A 1 39  ? 1.29905   -5.16898  32.40673  1.000 14.75177  ? 31  ASP A HA   1 
ATOM   502  H HB2  . ASP A 1 39  ? 0.22066   -6.88570  34.36742  1.000 16.71391  ? 31  ASP A HB2  1 
ATOM   503  H HB3  . ASP A 1 39  ? 0.72631   -5.42962  34.75419  1.000 16.71391  ? 31  ASP A HB3  1 
ATOM   504  N N    . SER A 1 40  ? 3.11246   -7.43205  33.76311  1.000 9.64820   ? 32  SER A N    1 
ATOM   505  C CA   . SER A 1 40  ? 4.46847   -7.73727  34.20300  1.000 12.78173  ? 32  SER A CA   1 
ATOM   506  C C    . SER A 1 40  ? 5.48690   -7.42242  33.11532  1.000 13.23153  ? 32  SER A C    1 
ATOM   507  O O    . SER A 1 40  ? 6.53623   -6.82620  33.39334  1.000 12.44057  ? 32  SER A O    1 
ATOM   508  C CB   . SER A 1 40  ? 4.54588   -9.21051  34.60905  1.000 13.99594  ? 32  SER A CB   1 
ATOM   509  O OG   . SER A 1 40  ? 5.85329   -9.58674  35.00493  1.000 12.43839  ? 32  SER A OG   1 
ATOM   510  H H    . SER A 1 40  ? 2.58499   -8.11121  33.75191  1.000 11.59486  ? 32  SER A H    1 
ATOM   511  H HA   . SER A 1 40  ? 4.68733   -7.19254  34.97519  1.000 15.35510  ? 32  SER A HA   1 
ATOM   512  H HB2  . SER A 1 40  ? 3.94106   -9.36002  35.35253  1.000 16.81216  ? 32  SER A HB2  1 
ATOM   513  H HB3  . SER A 1 40  ? 4.28164   -9.75580  33.85160  1.000 16.81216  ? 32  SER A HB3  1 
ATOM   514  H HG   . SER A 1 40  ? 6.13555   -9.06347  35.59833  1.000 14.94309  ? 32  SER A HG   1 
ATOM   515  N N    . GLU A 1 41  ? 5.19649   -7.81440  31.86990  1.000 9.86581   ? 33  GLU A N    1 
ATOM   516  C CA   . GLU A 1 41  ? 6.13538   -7.56923  30.77711  1.000 10.79854  ? 33  GLU A CA   1 
ATOM   517  C C    . GLU A 1 41  ? 6.21214   -6.08495  30.41929  1.000 8.72982   ? 33  GLU A C    1 
ATOM   518  O O    . GLU A 1 41  ? 7.28918   -5.58949  30.05206  1.000 12.53163  ? 33  GLU A O    1 
ATOM   519  C CB   . GLU A 1 41  ? 5.73542   -8.40578  29.55478  1.000 14.28488  ? 33  GLU A CB   1 
ATOM   520  C CG   . GLU A 1 41  ? 5.88787   -9.90818  29.75998  1.000 11.16098  ? 33  GLU A CG   1 
ATOM   521  C CD   . GLU A 1 41  ? 7.32757   -10.31935 29.87153  1.000 13.55337  ? 33  GLU A CD   1 
ATOM   522  O OE1  . GLU A 1 41  ? 8.08111   -10.09353 28.91541  1.000 14.30586  ? 33  GLU A OE1  1 
ATOM   523  O OE2  . GLU A 1 41  ? 7.73738   -10.87412 30.91178  1.000 20.02940  ? 33  GLU A OE2  1 
ATOM   524  H H    . GLU A 1 41  ? 4.47361   -8.21771  31.63671  1.000 11.85599  ? 33  GLU A H    1 
ATOM   525  H HA   . GLU A 1 41  ? 7.02297   -7.84758  31.05207  1.000 12.97527  ? 33  GLU A HA   1 
ATOM   526  H HB2  . GLU A 1 41  ? 4.80463   -8.22856  29.34710  1.000 17.15887  ? 33  GLU A HB2  1 
ATOM   527  H HB3  . GLU A 1 41  ? 6.29676   -8.15107  28.80583  1.000 17.15887  ? 33  GLU A HB3  1 
ATOM   528  H HG2  . GLU A 1 41  ? 5.43516   -10.16563 30.57831  1.000 13.41019  ? 33  GLU A HG2  1 
ATOM   529  H HG3  . GLU A 1 41  ? 5.49754   -10.37429 29.00415  1.000 13.41019  ? 33  GLU A HG3  1 
ATOM   530  N N    . LEU A 1 42  ? 5.09094   -5.36335  30.51115  1.000 10.32742  ? 34  LEU A N    1 
ATOM   531  C CA   . LEU A 1 42  ? 5.13093   -3.92233  30.29738  1.000 10.76769  ? 34  LEU A CA   1 
ATOM   532  C C    . LEU A 1 42  ? 6.01420   -3.24366  31.34059  1.000 12.78532  ? 34  LEU A C    1 
ATOM   533  O O    . LEU A 1 42  ? 6.79549   -2.34576  31.00804  1.000 12.22558  ? 34  LEU A O    1 
ATOM   534  C CB   . LEU A 1 42  ? 3.71823   -3.33135  30.32429  1.000 9.39619   ? 34  LEU A CB   1 
ATOM   535  C CG   . LEU A 1 42  ? 2.87100   -3.62404  29.08366  1.000 9.06889   ? 34  LEU A CG   1 
ATOM   536  C CD1  . LEU A 1 42  ? 1.43792   -3.14480  29.26503  1.000 14.43696  ? 34  LEU A CD1  1 
ATOM   537  C CD2  . LEU A 1 42  ? 3.47690   -3.02618  27.81972  1.000 11.80262  ? 34  LEU A CD2  1 
ATOM   538  H H    . LEU A 1 42  ? 4.31230   -5.68034  30.69234  1.000 12.40992  ? 34  LEU A H    1 
ATOM   539  H HA   . LEU A 1 42  ? 5.50238   -3.74989  29.41807  1.000 12.93825  ? 34  LEU A HA   1 
ATOM   540  H HB2  . LEU A 1 42  ? 3.24835   -3.69560  31.09074  1.000 11.29245  ? 34  LEU A HB2  1 
ATOM   541  H HB3  . LEU A 1 42  ? 3.79086   -2.36762  30.40696  1.000 11.29245  ? 34  LEU A HB3  1 
ATOM   542  H HG   . LEU A 1 42  ? 2.85478   -4.58693  28.96758  1.000 10.89969  ? 34  LEU A HG   1 
ATOM   543  H HD11 . LEU A 1 42  ? 0.94784   -3.29582  28.44167  1.000 17.34137  ? 34  LEU A HD11 1 
ATOM   544  H HD12 . LEU A 1 42  ? 1.02797   -3.64213  29.98995  1.000 17.34137  ? 34  LEU A HD12 1 
ATOM   545  H HD13 . LEU A 1 42  ? 1.44585   -2.19814  29.47637  1.000 17.34137  ? 34  LEU A HD13 1 
ATOM   546  H HD21 . LEU A 1 42  ? 2.85229   -3.13899  27.08621  1.000 14.18016  ? 34  LEU A HD21 1 
ATOM   547  H HD22 . LEU A 1 42  ? 3.64730   -2.08268  27.96694  1.000 14.18016  ? 34  LEU A HD22 1 
ATOM   548  H HD23 . LEU A 1 42  ? 4.30780   -3.48518  27.62018  1.000 14.18016  ? 34  LEU A HD23 1 
ATOM   549  N N    . ARG A 1 43  ? 5.93043   -3.66817  32.61024  1.000 13.00067  ? 35  ARG A N    1 
ATOM   550  C CA   . ARG A 1 43  ? 6.81311   -3.06732  33.61111  1.000 11.81321  ? 35  ARG A CA   1 
ATOM   551  C C    . ARG A 1 43  ? 8.27483   -3.33295  33.27397  1.000 13.89145  ? 35  ARG A C    1 
ATOM   552  O O    . ARG A 1 43  ? 9.12808   -2.45725  33.44661  1.000 13.13207  ? 35  ARG A O    1 
ATOM   553  C CB   . ARG A 1 43  ? 6.49564   -3.58629  35.01405  1.000 12.19668  ? 35  ARG A CB   1 
ATOM   554  C CG   . ARG A 1 43  ? 5.24326   -3.02446  35.61468  1.000 14.27975  ? 35  ARG A CG   1 
ATOM   555  C CD   . ARG A 1 43  ? 5.23031   -3.22658  37.13619  1.000 13.92005  ? 35  ARG A CD   1 
ATOM   556  N NE   . ARG A 1 43  ? 4.36721   -2.28976  37.83301  1.000 22.75926  ? 35  ARG A NE   1 
ATOM   557  C CZ   . ARG A 1 43  ? 4.04673   -2.38127  39.12309  1.000 55.38417  ? 35  ARG A CZ   1 
ATOM   558  N NH1  . ARG A 1 43  ? 4.49399   -3.39678  39.85470  1.000 36.65466  ? 35  ARG A NH1  1 
ATOM   559  N NH2  . ARG A 1 43  ? 3.27627   -1.45343  39.68843  1.000 23.86085  ? 35  ARG A NH2  1 
ATOM   560  H H    . ARG A 1 43  ? 5.39493   -4.27471  32.90170  1.000 15.61782  ? 35  ARG A H    1 
ATOM   561  H HA   . ARG A 1 43  ? 6.65708   -2.10996  33.61363  1.000 14.19288  ? 35  ARG A HA   1 
ATOM   562  H HB2  . ARG A 1 43  ? 6.39354   -4.54995  34.97135  1.000 14.65304  ? 35  ARG A HB2  1 
ATOM   563  H HB3  . ARG A 1 43  ? 7.23168   -3.35640  35.60252  1.000 14.65304  ? 35  ARG A HB3  1 
ATOM   564  H HG2  . ARG A 1 43  ? 5.19375   -2.07348  35.43006  1.000 17.15273  ? 35  ARG A HG2  1 
ATOM   565  H HG3  . ARG A 1 43  ? 4.47215   -3.47621  35.23757  1.000 17.15273  ? 35  ARG A HG3  1 
ATOM   566  H HD2  . ARG A 1 43  ? 4.91518   -4.12297  37.33134  1.000 16.72108  ? 35  ARG A HD2  1 
ATOM   567  H HD3  . ARG A 1 43  ? 6.13129   -3.11030  37.47621  1.000 16.72108  ? 35  ARG A HD3  1 
ATOM   568  H HE   . ARG A 1 43  ? 4.04151   -1.63279  37.38366  1.000 27.32814  ? 35  ARG A HE   1 
ATOM   569  H HH11 . ARG A 1 43  ? 4.99260   -3.99857  39.49575  1.000 44.00262  ? 35  ARG A HH11 1 
ATOM   570  H HH12 . ARG A 1 43  ? 4.28477   -3.45208  40.68702  1.000 44.00262  ? 35  ARG A HH12 1 
ATOM   571  H HH21 . ARG A 1 43  ? 2.98449   -0.79340  39.22063  1.000 28.65005  ? 35  ARG A HH21 1 
ATOM   572  H HH22 . ARG A 1 43  ? 3.07059   -1.51437  40.52124  1.000 28.65005  ? 35  ARG A HH22 1 
ATOM   573  N N    . LYS A 1 44  ? 8.58723   -4.53856  32.79942  1.000 11.69576  ? 36  LYS A N    1 
ATOM   574  C CA   . LYS A 1 44  ? 9.94759   -4.82182  32.36068  1.000 9.58873   ? 36  LYS A CA   1 
ATOM   575  C C    . LYS A 1 44  ? 10.34548  -3.91086  31.20415  1.000 12.77928  ? 36  LYS A C    1 
ATOM   576  O O    . LYS A 1 44  ? 11.46484  -3.38667  31.16314  1.000 12.26771  ? 36  LYS A O    1 
ATOM   577  C CB   . LYS A 1 44  ? 10.06031  -6.28455  31.94498  1.000 12.63131  ? 36  LYS A CB   1 
ATOM   578  C CG   . LYS A 1 44  ? 10.14635  -7.25903  33.10468  1.000 15.03260  ? 36  LYS A CG   1 
ATOM   579  C CD   . LYS A 1 44  ? 10.39526  -8.68723  32.56550  1.000 17.86425  ? 36  LYS A CD   1 
ATOM   580  C CE   . LYS A 1 44  ? 10.47610  -9.69956  33.69098  1.000 33.66157  ? 36  LYS A CE   1 
ATOM   581  N NZ   . LYS A 1 44  ? 10.57969  -11.08162 33.14427  1.000 30.73932  ? 36  LYS A NZ   1 
ATOM   582  H H    . LYS A 1 44  ? 8.03909   -5.19682  32.72308  1.000 14.05194  ? 36  LYS A H    1 
ATOM   583  H HA   . LYS A 1 44  ? 10.55923  -4.66585  33.09721  1.000 11.52350  ? 36  LYS A HA   1 
ATOM   584  H HB2  . LYS A 1 44  ? 9.27780   -6.51891  31.42186  1.000 15.17459  ? 36  LYS A HB2  1 
ATOM   585  H HB3  . LYS A 1 44  ? 10.86194  -6.39340  31.40979  1.000 15.17459  ? 36  LYS A HB3  1 
ATOM   586  H HG2  . LYS A 1 44  ? 10.88155  -7.01214  33.68728  1.000 18.05615  ? 36  LYS A HG2  1 
ATOM   587  H HG3  . LYS A 1 44  ? 9.31311   -7.25302  33.60125  1.000 18.05615  ? 36  LYS A HG3  1 
ATOM   588  H HD2  . LYS A 1 44  ? 9.66552   -8.94100  31.97901  1.000 21.45413  ? 36  LYS A HD2  1 
ATOM   589  H HD3  . LYS A 1 44  ? 11.23393  -8.70519  32.07846  1.000 21.45413  ? 36  LYS A HD3  1 
ATOM   590  H HE2  . LYS A 1 44  ? 11.26119  -9.52159  34.23216  1.000 40.41090  ? 36  LYS A HE2  1 
ATOM   591  H HE3  . LYS A 1 44  ? 9.67664   -9.64239  34.23732  1.000 40.41090  ? 36  LYS A HE3  1 
ATOM   592  H HZ1  . LYS A 1 44  ? 10.71371  -11.66149 33.80601  1.000 36.90421  ? 36  LYS A HZ1  1 
ATOM   593  H HZ2  . LYS A 1 44  ? 9.82853   -11.29768 32.71861  1.000 36.90421  ? 36  LYS A HZ2  1 
ATOM   594  H HZ3  . LYS A 1 44  ? 11.26030  -11.13282 32.57310  1.000 36.90421  ? 36  LYS A HZ3  1 
ATOM   595  N N    . LEU A 1 45  ? 9.44009   -3.71723  30.24867  1.000 14.55483  ? 37  LEU A N    1 
ATOM   596  C CA   . LEU A 1 45  ? 9.75976   -2.87628  29.09955  1.000 13.84739  ? 37  LEU A CA   1 
ATOM   597  C C    . LEU A 1 45  ? 10.00965  -1.43970  29.54171  1.000 12.87265  ? 37  LEU A C    1 
ATOM   598  O O    . LEU A 1 45  ? 10.99019  -0.80174  29.13431  1.000 10.43384  ? 37  LEU A O    1 
ATOM   599  C CB   . LEU A 1 45  ? 8.62664   -2.95341  28.07557  1.000 9.62297   ? 37  LEU A CB   1 
ATOM   600  C CG   . LEU A 1 45  ? 8.76534   -2.03118  26.86061  1.000 7.93448   ? 37  LEU A CG   1 
ATOM   601  C CD1  . LEU A 1 45  ? 10.03938  -2.32202  26.08964  1.000 11.17737  ? 37  LEU A CD1  1 
ATOM   602  C CD2  . LEU A 1 45  ? 7.53902   -2.14972  25.97437  1.000 10.41133  ? 37  LEU A CD2  1 
ATOM   603  H H    . LEU A 1 45  ? 8.64896   -4.05436  30.24146  1.000 17.48282  ? 37  LEU A H    1 
ATOM   604  H HA   . LEU A 1 45  ? 10.56734  -3.20126  28.67165  1.000 16.63389  ? 37  LEU A HA   1 
ATOM   605  H HB2  . LEU A 1 45  ? 8.57939   -3.86342  27.74308  1.000 11.56459  ? 37  LEU A HB2  1 
ATOM   606  H HB3  . LEU A 1 45  ? 7.79772   -2.71982  28.52192  1.000 11.56459  ? 37  LEU A HB3  1 
ATOM   607  H HG   . LEU A 1 45  ? 8.82793   -1.11226  27.16489  1.000 9.53839   ? 37  LEU A HG   1 
ATOM   608  H HD11 . LEU A 1 45  ? 10.07516  -1.74605  25.30998  1.000 13.42987  ? 37  LEU A HD11 1 
ATOM   609  H HD12 . LEU A 1 45  ? 10.80213  -2.14959  26.66356  1.000 13.42987  ? 37  LEU A HD12 1 
ATOM   610  H HD13 . LEU A 1 45  ? 10.03637  -3.25203  25.81400  1.000 13.42987  ? 37  LEU A HD13 1 
ATOM   611  H HD21 . LEU A 1 45  ? 7.65576   -1.58256  25.19617  1.000 12.51062  ? 37  LEU A HD21 1 
ATOM   612  H HD22 . LEU A 1 45  ? 7.43735   -3.07390  25.69787  1.000 12.51062  ? 37  LEU A HD22 1 
ATOM   613  H HD23 . LEU A 1 45  ? 6.75842   -1.86670  26.47584  1.000 12.51062  ? 37  LEU A HD23 1 
ATOM   614  N N    . PHE A 1 46  ? 9.15998   -0.92961  30.42639  1.000 10.65253  ? 38  PHE A N    1 
ATOM   615  C CA   . PHE A 1 46  ? 9.30946   0.45877   30.83465  1.000 11.79846  ? 38  PHE A CA   1 
ATOM   616  C C    . PHE A 1 46  ? 10.58374  0.64272   31.65064  1.000 16.28618  ? 38  PHE A C    1 
ATOM   617  O O    . PHE A 1 46  ? 11.26164  1.67467   31.53521  1.000 13.61158  ? 38  PHE A O    1 
ATOM   618  C CB   . PHE A 1 46  ? 8.08147   0.91442   31.62795  1.000 14.42497  ? 38  PHE A CB   1 
ATOM   619  C CG   . PHE A 1 46  ? 6.77735   0.80945   30.87369  1.000 16.10391  ? 38  PHE A CG   1 
ATOM   620  C CD1  . PHE A 1 46  ? 6.73874   0.85777   29.48495  1.000 12.39868  ? 38  PHE A CD1  1 
ATOM   621  C CD2  . PHE A 1 46  ? 5.57464   0.67979   31.56243  1.000 8.87014   ? 38  PHE A CD2  1 
ATOM   622  C CE1  . PHE A 1 46  ? 5.52701   0.76550   28.80527  1.000 11.40643  ? 38  PHE A CE1  1 
ATOM   623  C CE2  . PHE A 1 46  ? 4.36405   0.58274   30.88340  1.000 12.53392  ? 38  PHE A CE2  1 
ATOM   624  C CZ   . PHE A 1 46  ? 4.33927   0.63246   29.49847  1.000 10.09077  ? 38  PHE A CZ   1 
ATOM   625  H H    . PHE A 1 46  ? 8.50828   -1.35367  30.79391  1.000 12.80005  ? 38  PHE A H    1 
ATOM   626  H HA   . PHE A 1 46  ? 9.36865   1.01914   30.04510  1.000 14.17518  ? 38  PHE A HA   1 
ATOM   627  H HB2  . PHE A 1 46  ? 8.00538   0.36440   32.42331  1.000 17.32699  ? 38  PHE A HB2  1 
ATOM   628  H HB3  . PHE A 1 46  ? 8.20188   1.84396   31.87766  1.000 17.32699  ? 38  PHE A HB3  1 
ATOM   629  H HD1  . PHE A 1 46  ? 7.52981   0.95263   29.00525  1.000 14.89544  ? 38  PHE A HD1  1 
ATOM   630  H HD2  . PHE A 1 46  ? 5.58035   0.65766   32.49215  1.000 10.66120  ? 38  PHE A HD2  1 
ATOM   631  H HE1  . PHE A 1 46  ? 5.51707   0.79369   27.87576  1.000 13.70474  ? 38  PHE A HE1  1 
ATOM   632  H HE2  . PHE A 1 46  ? 3.57100   0.48445   31.35912  1.000 15.05772  ? 38  PHE A HE2  1 
ATOM   633  H HZ   . PHE A 1 46  ? 3.53168   0.57686   29.04064  1.000 12.12595  ? 38  PHE A HZ   1 
ATOM   634  N N    . ALA A 1 47  ? 10.92696  -0.35412  32.47766  1.000 13.07833  ? 39  ALA A N    1 
ATOM   635  C CA   . ALA A 1 47  ? 12.15239  -0.28014  33.26607  1.000 16.73701  ? 39  ALA A CA   1 
ATOM   636  C C    . ALA A 1 47  ? 13.37625  -0.35814  32.36877  1.000 15.75930  ? 39  ALA A C    1 
ATOM   637  O O    . ALA A 1 47  ? 14.36746  0.34138   32.60296  1.000 14.28123  ? 39  ALA A O    1 
ATOM   638  C CB   . ALA A 1 47  ? 12.19730  -1.40590  34.30331  1.000 14.41180  ? 39  ALA A CB   1 
ATOM   639  H H    . ALA A 1 47  ? 10.47054  -1.07333  32.59606  1.000 15.71102  ? 39  ALA A H    1 
ATOM   640  H HA   . ALA A 1 47  ? 12.16016  0.56541   33.74136  1.000 20.10144  ? 39  ALA A HA   1 
ATOM   641  H HB1  . ALA A 1 47  ? 13.01226  -1.32417  34.82299  1.000 17.31118  ? 39  ALA A HB1  1 
ATOM   642  H HB2  . ALA A 1 47  ? 11.42494  -1.33016  34.88522  1.000 17.31118  ? 39  ALA A HB2  1 
ATOM   643  H HB3  . ALA A 1 47  ? 12.18249  -2.25982  33.84342  1.000 17.31118  ? 39  ALA A HB3  1 
ATOM   644  N N    . PHE A 1 48  ? 13.32371  -1.21708  31.34495  1.000 11.43750  ? 40  PHE A N    1 
ATOM   645  C CA   . PHE A 1 48  ? 14.37936  -1.27255  30.34319  1.000 11.93096  ? 40  PHE A CA   1 
ATOM   646  C C    . PHE A 1 48  ? 14.55748  0.08567   29.67343  1.000 11.62754  ? 40  PHE A C    1 
ATOM   647  O O    . PHE A 1 48  ? 15.67827  0.58549   29.52395  1.000 11.41469  ? 40  PHE A O    1 
ATOM   648  C CB   . PHE A 1 48  ? 14.05213  -2.36649  29.31471  1.000 13.60146  ? 40  PHE A CB   1 
ATOM   649  C CG   . PHE A 1 48  ? 14.93128  -2.32042  28.09717  1.000 11.17639  ? 40  PHE A CG   1 
ATOM   650  C CD1  . PHE A 1 48  ? 16.21443  -2.85956  28.12844  1.000 18.27728  ? 40  PHE A CD1  1 
ATOM   651  C CD2  . PHE A 1 48  ? 14.49288  -1.71382  26.93234  1.000 11.73279  ? 40  PHE A CD2  1 
ATOM   652  C CE1  . PHE A 1 48  ? 17.03908  -2.79022  27.00636  1.000 18.72936  ? 40  PHE A CE1  1 
ATOM   653  C CE2  . PHE A 1 48  ? 15.31590  -1.63741  25.82024  1.000 17.76197  ? 40  PHE A CE2  1 
ATOM   654  C CZ   . PHE A 1 48  ? 16.58193  -2.17831  25.85963  1.000 16.77532  ? 40  PHE A CZ   1 
ATOM   655  H H    . PHE A 1 48  ? 12.68504  -1.77726  31.21120  1.000 13.74203  ? 40  PHE A H    1 
ATOM   656  H HA   . PHE A 1 48  ? 15.22064  -1.50491  30.76646  1.000 14.33417  ? 40  PHE A HA   1 
ATOM   657  H HB2  . PHE A 1 48  ? 14.16722  -3.23426  29.73259  1.000 16.33878  ? 40  PHE A HB2  1 
ATOM   658  H HB3  . PHE A 1 48  ? 13.13341  -2.25795  29.02305  1.000 16.33878  ? 40  PHE A HB3  1 
ATOM   659  H HD1  . PHE A 1 48  ? 16.52398  -3.26918  28.90387  1.000 21.94976  ? 40  PHE A HD1  1 
ATOM   660  H HD2  . PHE A 1 48  ? 13.63627  -1.35357  26.89593  1.000 14.09637  ? 40  PHE A HD2  1 
ATOM   661  H HE1  . PHE A 1 48  ? 17.89400  -3.15541  27.03180  1.000 22.49225  ? 40  PHE A HE1  1 
ATOM   662  H HE2  . PHE A 1 48  ? 15.01302  -1.22030  25.04617  1.000 21.33139  ? 40  PHE A HE2  1 
ATOM   663  H HZ   . PHE A 1 48  ? 17.12998  -2.13037  25.10980  1.000 20.14740  ? 40  PHE A HZ   1 
ATOM   664  N N    . LEU A 1 49  ? 13.45577  0.70079   29.25337  1.000 11.45076  ? 41  LEU A N    1 
ATOM   665  C CA   . LEU A 1 49  ? 13.56217  1.98879   28.58641  1.000 9.40478   ? 41  LEU A CA   1 
ATOM   666  C C    . LEU A 1 49  ? 14.17290  3.02484   29.51830  1.000 11.37554  ? 41  LEU A C    1 
ATOM   667  O O    . LEU A 1 49  ? 15.06606  3.78322   29.12231  1.000 13.60573  ? 41  LEU A O    1 
ATOM   668  C CB   . LEU A 1 49  ? 12.18948  2.44359   28.09424  1.000 13.01899  ? 41  LEU A CB   1 
ATOM   669  C CG   . LEU A 1 49  ? 11.62043  1.57845   26.96053  1.000 13.75893  ? 41  LEU A CG   1 
ATOM   670  C CD1  . LEU A 1 49  ? 10.20102  2.02128   26.63975  1.000 11.84093  ? 41  LEU A CD1  1 
ATOM   671  C CD2  . LEU A 1 49  ? 12.49179  1.61032   25.72831  1.000 13.11714  ? 41  LEU A CD2  1 
ATOM   672  H H    . LEU A 1 49  ? 12.65495  0.39975   29.34089  1.000 13.75794  ? 41  LEU A H    1 
ATOM   673  H HA   . LEU A 1 49  ? 14.13763  1.89723   27.81094  1.000 11.30276  ? 41  LEU A HA   1 
ATOM   674  H HB2  . LEU A 1 49  ? 11.56561  2.40831   28.83615  1.000 15.63981  ? 41  LEU A HB2  1 
ATOM   675  H HB3  . LEU A 1 49  ? 12.26263  3.35316   27.76526  1.000 15.63981  ? 41  LEU A HB3  1 
ATOM   676  H HG   . LEU A 1 49  ? 11.60106  0.65455   27.25540  1.000 16.52774  ? 41  LEU A HG   1 
ATOM   677  H HD11 . LEU A 1 49  ? 9.85485   1.47356   25.91790  1.000 14.22613  ? 41  LEU A HD11 1 
ATOM   678  H HD12 . LEU A 1 49  ? 9.65004   1.91292   27.43069  1.000 14.22613  ? 41  LEU A HD12 1 
ATOM   679  H HD13 . LEU A 1 49  ? 10.21410  2.95318   26.37087  1.000 14.22613  ? 41  LEU A HD13 1 
ATOM   680  H HD21 . LEU A 1 49  ? 12.04383  1.13323   25.01233  1.000 15.75759  ? 41  LEU A HD21 1 
ATOM   681  H HD22 . LEU A 1 49  ? 12.63885  2.53346   25.46931  1.000 15.75759  ? 41  LEU A HD22 1 
ATOM   682  H HD23 . LEU A 1 49  ? 13.33957  1.18426   25.92992  1.000 15.75759  ? 41  LEU A HD23 1 
ATOM   683  N N    . SER A 1 50  ? 13.69661  3.06375   30.76585  1.000 10.42178  ? 42  SER A N    1 
ATOM   684  C CA   . SER A 1 50  ? 14.27394  3.96309   31.76262  1.000 13.03099  ? 42  SER A CA   1 
ATOM   685  C C    . SER A 1 50  ? 15.77300  3.73484   31.91526  1.000 14.15777  ? 42  SER A C    1 
ATOM   686  O O    . SER A 1 50  ? 16.55532  4.69487   32.02244  1.000 16.65044  ? 42  SER A O    1 
ATOM   687  C CB   . SER A 1 50  ? 13.55932  3.76635   33.10204  1.000 23.94602  ? 42  SER A CB   1 
ATOM   688  O OG   . SER A 1 50  ? 14.14178  4.58063   34.09903  1.000 34.48863  ? 42  SER A OG   1 
ATOM   689  H H    . SER A 1 50  ? 13.04544  2.58343   31.05719  1.000 12.52315  ? 42  SER A H    1 
ATOM   690  H HA   . SER A 1 50  ? 14.14329  4.88057   31.47618  1.000 15.65421  ? 42  SER A HA   1 
ATOM   691  H HB2  . SER A 1 50  ? 12.62525  4.00776   33.00139  1.000 28.75224  ? 42  SER A HB2  1 
ATOM   692  H HB3  . SER A 1 50  ? 13.63489  2.83661   33.36806  1.000 28.75224  ? 42  SER A HB3  1 
ATOM   693  H HG   . SER A 1 50  ? 14.04111  5.39120   33.90297  1.000 41.40338  ? 42  SER A HG   1 
ATOM   694  N N    . SER A 1 51  ? 16.19600  2.47137   31.93679  1.000 15.52259  ? 43  SER A N    1 
ATOM   695  C CA   . SER A 1 51  ? 17.61278  2.16727   32.10254  1.000 15.84536  ? 43  SER A CA   1 
ATOM   696  C C    . SER A 1 51  ? 18.45707  2.69273   30.95360  1.000 19.70145  ? 43  SER A C    1 
ATOM   697  O O    . SER A 1 51  ? 19.66672  2.88339   31.12393  1.000 19.54721  ? 43  SER A O    1 
ATOM   698  C CB   . SER A 1 51  ? 17.81614  0.66395   32.23742  1.000 14.86951  ? 43  SER A CB   1 
ATOM   699  O OG   . SER A 1 51  ? 17.83135  0.02232   30.97095  1.000 16.91869  ? 43  SER A OG   1 
ATOM   700  H H    . SER A 1 51  ? 15.68859  1.78146   31.85838  1.000 18.64413  ? 43  SER A H    1 
ATOM   701  H HA   . SER A 1 51  ? 17.92046  2.58996   32.91959  1.000 19.03146  ? 43  SER A HA   1 
ATOM   702  H HB2  . SER A 1 51  ? 18.66371  0.50162   32.68033  1.000 17.86044  ? 43  SER A HB2  1 
ATOM   703  H HB3  . SER A 1 51  ? 17.09016  0.29639   32.76539  1.000 17.86044  ? 43  SER A HB3  1 
ATOM   704  H HG   . SER A 1 51  ? 17.96285  -0.80164  31.06789  1.000 20.31945  ? 43  SER A HG   1 
ATOM   705  N N    . LYS A 1 52  ? 17.84893  2.94107   29.79716  1.000 16.02801  ? 44  LYS A N    1 
ATOM   706  C CA   . LYS A 1 52  ? 18.54363  3.47414   28.63805  1.000 15.12784  ? 44  LYS A CA   1 
ATOM   707  C C    . LYS A 1 52  ? 18.32855  4.97219   28.47610  1.000 18.55390  ? 44  LYS A C    1 
ATOM   708  O O    . LYS A 1 52  ? 18.74312  5.53392   27.45761  1.000 17.41581  ? 44  LYS A O    1 
ATOM   709  C CB   . LYS A 1 52  ? 18.08668  2.74853   27.36624  1.000 16.11387  ? 44  LYS A CB   1 
ATOM   710  C CG   . LYS A 1 52  ? 18.24828  1.22676   27.39844  1.000 14.22585  ? 44  LYS A CG   1 
ATOM   711  C CD   . LYS A 1 52  ? 19.70905  0.83149   27.51164  1.000 15.37698  ? 44  LYS A CD   1 
ATOM   712  C CE   . LYS A 1 52  ? 19.88483  -0.66945  27.42779  1.000 21.45684  ? 44  LYS A CE   1 
ATOM   713  N NZ   . LYS A 1 52  ? 21.31421  -1.04660  27.58792  1.000 27.53255  ? 44  LYS A NZ   1 
ATOM   714  H H    . LYS A 1 52  ? 17.01120  2.80397   29.65928  1.000 19.25064  ? 44  LYS A H    1 
ATOM   715  H HA   . LYS A 1 52  ? 19.49387  3.31373   28.74854  1.000 18.17043  ? 44  LYS A HA   1 
ATOM   716  H HB2  . LYS A 1 52  ? 17.14597  2.93851   27.22527  1.000 19.35367  ? 44  LYS A HB2  1 
ATOM   717  H HB3  . LYS A 1 52  ? 18.60792  3.08092   26.61876  1.000 19.35367  ? 44  LYS A HB3  1 
ATOM   718  H HG2  . LYS A 1 52  ? 17.77405  0.86841   28.16499  1.000 17.08804  ? 44  LYS A HG2  1 
ATOM   719  H HG3  . LYS A 1 52  ? 17.89114  0.84731   26.58029  1.000 17.08804  ? 44  LYS A HG3  1 
ATOM   720  H HD2  . LYS A 1 52  ? 20.20917  1.23811   26.78676  1.000 18.46940  ? 44  LYS A HD2  1 
ATOM   721  H HD3  . LYS A 1 52  ? 20.05821  1.13225   28.36518  1.000 18.46940  ? 44  LYS A HD3  1 
ATOM   722  H HE2  . LYS A 1 52  ? 19.37367  -1.09477  28.13399  1.000 25.76523  ? 44  LYS A HE2  1 
ATOM   723  H HE3  . LYS A 1 52  ? 19.57928  -0.98288  26.56217  1.000 25.76523  ? 44  LYS A HE3  1 
ATOM   724  H HZ1  . LYS A 1 52  ? 21.40645  -1.92868  27.51357  1.000 33.05609  ? 44  LYS A HZ1  1 
ATOM   725  H HZ2  . LYS A 1 52  ? 21.80561  -0.65088  26.96020  1.000 33.05609  ? 44  LYS A HZ2  1 
ATOM   726  H HZ3  . LYS A 1 52  ? 21.60841  -0.79187  28.38833  1.000 33.05609  ? 44  LYS A HZ3  1 
ATOM   727  N N    . GLY A 1 53  ? 17.64622  5.61778   29.42641  1.000 14.75891  ? 45  GLY A N    1 
ATOM   728  C CA   . GLY A 1 53  ? 17.34824  7.03067   29.31237  1.000 18.45623  ? 45  GLY A CA   1 
ATOM   729  C C    . GLY A 1 53  ? 16.25371  7.37532   28.32949  1.000 18.74216  ? 45  GLY A C    1 
ATOM   730  O O    . GLY A 1 53  ? 16.17178  8.52585   27.89233  1.000 19.38784  ? 45  GLY A O    1 
ATOM   731  H H    . GLY A 1 53  ? 17.34751  5.25261   30.14546  1.000 17.72771  ? 45  GLY A H    1 
ATOM   732  H HA2  . GLY A 1 53  ? 17.07794  7.36182   30.18310  1.000 22.16450  ? 45  GLY A HA2  1 
ATOM   733  H HA3  . GLY A 1 53  ? 18.15252  7.49565   29.03339  1.000 22.16450  ? 45  GLY A HA3  1 
ATOM   734  N N    . ILE A 1 54  ? 15.37753  6.42758   28.00773  1.000 13.16586  ? 46  ILE A N    1 
ATOM   735  C CA   . ILE A 1 54  ? 14.30952  6.62631   27.03616  1.000 11.68909  ? 46  ILE A CA   1 
ATOM   736  C C    . ILE A 1 54  ? 13.02207  6.87342   27.80016  1.000 10.50588  ? 46  ILE A C    1 
ATOM   737  O O    . ILE A 1 54  ? 12.68175  6.11089   28.71167  1.000 14.73380  ? 46  ILE A O    1 
ATOM   738  C CB   . ILE A 1 54  ? 14.18109  5.40412   26.10922  1.000 11.33575  ? 46  ILE A CB   1 
ATOM   739  C CG1  . ILE A 1 54  ? 15.49571  5.18448   25.34849  1.000 12.05898  ? 46  ILE A CG1  1 
ATOM   740  C CG2  . ILE A 1 54  ? 13.03924  5.57186   25.14258  1.000 11.85415  ? 46  ILE A CG2  1 
ATOM   741  C CD1  . ILE A 1 54  ? 15.52818  3.86724   24.57362  1.000 15.75227  ? 46  ILE A CD1  1 
ATOM   742  H H    . ILE A 1 54  ? 15.38286  5.63855   28.34979  1.000 15.81605  ? 46  ILE A H    1 
ATOM   743  H HA   . ILE A 1 54  ? 14.49726  7.40535   26.48959  1.000 14.04393  ? 46  ILE A HA   1 
ATOM   744  H HB   . ILE A 1 54  ? 13.99661  4.62662   26.65909  1.000 13.61992  ? 46  ILE A HB   1 
ATOM   745  H HG12 . ILE A 1 54  ? 15.61593  5.90771   24.71336  1.000 14.48779  ? 46  ILE A HG12 1 
ATOM   746  H HG13 . ILE A 1 54  ? 16.22872  5.17552   25.98372  1.000 14.48779  ? 46  ILE A HG13 1 
ATOM   747  H HG21 . ILE A 1 54  ? 13.00979  4.80286   24.55210  1.000 14.24201  ? 46  ILE A HG21 1 
ATOM   748  H HG22 . ILE A 1 54  ? 12.21007  5.63766   25.64164  1.000 14.24201  ? 46  ILE A HG22 1 
ATOM   749  H HG23 . ILE A 1 54  ? 13.17927  6.38064   24.62569  1.000 14.24201  ? 46  ILE A HG23 1 
ATOM   750  H HD11 . ILE A 1 54  ? 16.40897  3.75162   24.18410  1.000 18.91974  ? 46  ILE A HD11 1 
ATOM   751  H HD12 . ILE A 1 54  ? 15.33777  3.13734   25.18345  1.000 18.91974  ? 46  ILE A HD12 1 
ATOM   752  H HD13 . ILE A 1 54  ? 14.85791  3.89636   23.87306  1.000 18.91974  ? 46  ILE A HD13 1 
ATOM   753  N N    . LYS A 1 55  ? 12.30586  7.92888   27.42273  1.000 9.44384   ? 47  LYS A N    1 
ATOM   754  C CA   . LYS A 1 55  ? 11.08038  8.29513   28.10571  1.000 10.77526  ? 47  LYS A CA   1 
ATOM   755  C C    . LYS A 1 55  ? 9.92160   7.41679   27.65741  1.000 13.42930  ? 47  LYS A C    1 
ATOM   756  O O    . LYS A 1 55  ? 9.85109   6.97371   26.50604  1.000 12.90789  ? 47  LYS A O    1 
ATOM   757  C CB   . LYS A 1 55  ? 10.76877  9.76549   27.85259  1.000 12.35026  ? 47  LYS A CB   1 
ATOM   758  C CG   . LYS A 1 55  ? 11.78191  10.68587  28.56024  1.000 15.32374  ? 47  LYS A CG   1 
ATOM   759  C CD   . LYS A 1 55  ? 11.64487  12.14070  28.17742  1.000 24.62083  ? 47  LYS A CD   1 
ATOM   760  C CE   . LYS A 1 55  ? 12.79611  12.94152  28.79763  1.000 32.79516  ? 47  LYS A CE   1 
ATOM   761  N NZ   . LYS A 1 55  ? 12.56013  14.40452  28.80667  1.000 36.44195  ? 47  LYS A NZ   1 
ATOM   762  H H    . LYS A 1 55  ? 12.51322  8.44896   26.76995  1.000 11.34963  ? 47  LYS A H    1 
ATOM   763  H HA   . LYS A 1 55  ? 11.18395  8.16613   29.06150  1.000 12.94734  ? 47  LYS A HA   1 
ATOM   764  H HB2  . LYS A 1 55  ? 10.80842  9.94231   26.89967  1.000 14.83734  ? 47  LYS A HB2  1 
ATOM   765  H HB3  . LYS A 1 55  ? 9.88269   9.96843   28.19108  1.000 14.83734  ? 47  LYS A HB3  1 
ATOM   766  H HG2  . LYS A 1 55  ? 11.65063  10.61819  29.51893  1.000 18.40551  ? 47  LYS A HG2  1 
ATOM   767  H HG3  . LYS A 1 55  ? 12.67962  10.40159  28.32743  1.000 18.40551  ? 47  LYS A HG3  1 
ATOM   768  H HD2  . LYS A 1 55  ? 11.68331  12.23226  27.21251  1.000 29.56201  ? 47  LYS A HD2  1 
ATOM   769  H HD3  . LYS A 1 55  ? 10.80396  12.49102  28.51067  1.000 29.56201  ? 47  LYS A HD3  1 
ATOM   770  H HE2  . LYS A 1 55  ? 12.91806  12.65505  29.71630  1.000 39.37121  ? 47  LYS A HE2  1 
ATOM   771  H HE3  . LYS A 1 55  ? 13.60438  12.77459  28.28799  1.000 39.37121  ? 47  LYS A HE3  1 
ATOM   772  H HZ1  . LYS A 1 55  ? 13.18181  14.81010  29.29771  1.000 43.74736  ? 47  LYS A HZ1  1 
ATOM   773  H HZ2  . LYS A 1 55  ? 12.59425  14.72349  27.97649  1.000 43.74736  ? 47  LYS A HZ2  1 
ATOM   774  H HZ3  . LYS A 1 55  ? 11.75890  14.58148  29.15138  1.000 43.74736  ? 47  LYS A HZ3  1 
ATOM   775  N N    . VAL A 1 56  ? 8.99925   7.18292   28.58861  1.000 9.98607   ? 48  VAL A N    1 
ATOM   776  C CA   . VAL A 1 56  ? 7.77293   6.43049   28.33930  1.000 10.93656  ? 48  VAL A CA   1 
ATOM   777  C C    . VAL A 1 56  ? 6.61024   7.41010   28.38677  1.000 10.11199  ? 48  VAL A C    1 
ATOM   778  O O    . VAL A 1 56  ? 6.38094   8.04232   29.42198  1.000 11.73845  ? 48  VAL A O    1 
ATOM   779  C CB   . VAL A 1 56  ? 7.57872   5.31481   29.37484  1.000 14.67856  ? 48  VAL A CB   1 
ATOM   780  C CG1  . VAL A 1 56  ? 6.20347   4.67572   29.23559  1.000 11.81800  ? 48  VAL A CG1  1 
ATOM   781  C CG2  . VAL A 1 56  ? 8.67440   4.28981   29.22716  1.000 12.41753  ? 48  VAL A CG2  1 
ATOM   782  H H    . VAL A 1 56  ? 9.06468   7.45999   29.40012  1.000 12.00030  ? 48  VAL A H    1 
ATOM   783  H HA   . VAL A 1 56  ? 7.81286   6.03325   27.45527  1.000 13.14090  ? 48  VAL A HA   1 
ATOM   784  H HB   . VAL A 1 56  ? 7.62891   5.69221   30.26700  1.000 17.63130  ? 48  VAL A HB   1 
ATOM   785  H HG11 . VAL A 1 56  ? 6.17066   3.87480   29.78180  1.000 14.19862  ? 48  VAL A HG11 1 
ATOM   786  H HG12 . VAL A 1 56  ? 5.53015   5.30716   29.53363  1.000 14.19862  ? 48  VAL A HG12 1 
ATOM   787  H HG13 . VAL A 1 56  ? 6.05402   4.44761   28.30471  1.000 14.19862  ? 48  VAL A HG13 1 
ATOM   788  H HG21 . VAL A 1 56  ? 8.57361   3.61783   29.91939  1.000 14.91805  ? 48  VAL A HG21 1 
ATOM   789  H HG22 . VAL A 1 56  ? 8.60448   3.87660   28.35236  1.000 14.91805  ? 48  VAL A HG22 1 
ATOM   790  H HG23 . VAL A 1 56  ? 9.53365   4.73087   29.31691  1.000 14.91805  ? 48  VAL A HG23 1 
ATOM   791  N N    . ILE A 1 57  ? 5.87185   7.51291   27.27521  1.000 8.40889   ? 49  ILE A N    1 
ATOM   792  C CA   . ILE A 1 57  ? 4.75445   8.43799   27.11871  1.000 11.72097  ? 49  ILE A CA   1 
ATOM   793  C C    . ILE A 1 57  ? 3.49242   7.62129   26.89823  1.000 13.65524  ? 49  ILE A C    1 
ATOM   794  O O    . ILE A 1 57  ? 3.48077   6.71971   26.05401  1.000 14.20719  ? 49  ILE A O    1 
ATOM   795  C CB   . ILE A 1 57  ? 4.98903   9.39306   25.93429  1.000 10.49223  ? 49  ILE A CB   1 
ATOM   796  C CG1  . ILE A 1 57  ? 6.26070   10.23209  26.16457  1.000 15.15861  ? 49  ILE A CG1  1 
ATOM   797  C CG2  . ILE A 1 57  ? 3.77852   10.27585  25.73440  1.000 13.81011  ? 49  ILE A CG2  1 
ATOM   798  C CD1  . ILE A 1 57  ? 6.83901   10.79656  24.88443  1.000 22.34796  ? 49  ILE A CD1  1 
ATOM   799  H H    . ILE A 1 57  ? 6.00870   7.03573   26.57296  1.000 10.10769  ? 49  ILE A H    1 
ATOM   800  H HA   . ILE A 1 57  ? 4.64711   8.96083   27.92865  1.000 14.08219  ? 49  ILE A HA   1 
ATOM   801  H HB   . ILE A 1 57  ? 5.12100   8.86900   25.12878  1.000 12.60770  ? 49  ILE A HB   1 
ATOM   802  H HG12 . ILE A 1 57  ? 6.04526   10.97588  26.74875  1.000 18.20735  ? 49  ILE A HG12 1 
ATOM   803  H HG13 . ILE A 1 57  ? 6.93689   9.67176   26.57650  1.000 18.20735  ? 49  ILE A HG13 1 
ATOM   804  H HG21 . ILE A 1 57  ? 3.99315   10.96386  25.08519  1.000 16.58916  ? 49  ILE A HG21 1 
ATOM   805  H HG22 . ILE A 1 57  ? 3.04226   9.73365   25.41061  1.000 16.58916  ? 49  ILE A HG22 1 
ATOM   806  H HG23 . ILE A 1 57  ? 3.54141   10.68337  26.58211  1.000 16.58916  ? 49  ILE A HG23 1 
ATOM   807  H HD11 . ILE A 1 57  ? 7.67830   11.23940  25.08539  1.000 26.83458  ? 49  ILE A HD11 1 
ATOM   808  H HD12 . ILE A 1 57  ? 6.98951   10.07066  24.25887  1.000 26.83458  ? 49  ILE A HD12 1 
ATOM   809  H HD13 . ILE A 1 57  ? 6.21113   11.43288  24.50790  1.000 26.83458  ? 49  ILE A HD13 1 
ATOM   810  N N    . PHE A 1 58  ? 2.42932   7.95037   27.63626  1.000 9.62421   ? 50  PHE A N    1 
ATOM   811  C CA   . PHE A 1 58  ? 1.08019   7.48339   27.34847  1.000 8.92451   ? 50  PHE A CA   1 
ATOM   812  C C    . PHE A 1 58  ? 0.32564   8.63473   26.69272  1.000 8.57123   ? 50  PHE A C    1 
ATOM   813  O O    . PHE A 1 58  ? 0.23910   9.72230   27.26444  1.000 12.97575  ? 50  PHE A O    1 
ATOM   814  C CB   . PHE A 1 58  ? 0.37110   7.02257   28.62257  1.000 9.82763   ? 50  PHE A CB   1 
ATOM   815  C CG   . PHE A 1 58  ? 1.03562   5.86208   29.29380  1.000 10.36573  ? 50  PHE A CG   1 
ATOM   816  C CD1  . PHE A 1 58  ? 1.12412   4.64136   28.65954  1.000 11.87328  ? 50  PHE A CD1  1 
ATOM   817  C CD2  . PHE A 1 58  ? 1.57787   5.99167   30.56069  1.000 11.60658  ? 50  PHE A CD2  1 
ATOM   818  C CE1  . PHE A 1 58  ? 1.75574   3.56992   29.25668  1.000 13.13958  ? 50  PHE A CE1  1 
ATOM   819  C CE2  . PHE A 1 58  ? 2.20081   4.90163   31.18962  1.000 10.30862  ? 50  PHE A CE2  1 
ATOM   820  C CZ   . PHE A 1 58  ? 2.28505   3.69133   30.53221  1.000 13.07563  ? 50  PHE A CZ   1 
ATOM   821  H H    . PHE A 1 58  ? 2.47040   8.45861   28.32879  1.000 11.56608  ? 50  PHE A H    1 
ATOM   822  H HA   . PHE A 1 58  ? 1.10739   6.72760   26.74106  1.000 10.72644  ? 50  PHE A HA   1 
ATOM   823  H HB2  . PHE A 1 58  ? 0.35275   7.75914   29.25347  1.000 11.81018  ? 50  PHE A HB2  1 
ATOM   824  H HB3  . PHE A 1 58  ? -0.53396  6.75614   28.39722  1.000 11.81018  ? 50  PHE A HB3  1 
ATOM   825  H HD1  . PHE A 1 58  ? 0.75131   4.53817   27.81380  1.000 14.26496  ? 50  PHE A HD1  1 
ATOM   826  H HD2  . PHE A 1 58  ? 1.52909   6.80977   31.00027  1.000 13.94492  ? 50  PHE A HD2  1 
ATOM   827  H HE1  . PHE A 1 58  ? 1.82678   2.76220   28.80123  1.000 15.78452  ? 50  PHE A HE1  1 
ATOM   828  H HE2  . PHE A 1 58  ? 2.55469   4.99489   32.04459  1.000 12.38737  ? 50  PHE A HE2  1 
ATOM   829  H HZ   . PHE A 1 58  ? 2.69358   2.96299   30.94149  1.000 15.70777  ? 50  PHE A HZ   1 
ATOM   830  N N    . LEU A 1 59  ? -0.16535  8.40906   25.47748  1.000 10.97772  ? 51  LEU A N    1 
ATOM   831  C CA   . LEU A 1 59  ? -0.89674  9.41590   24.71294  1.000 13.54837  ? 51  LEU A CA   1 
ATOM   832  C C    . LEU A 1 59  ? -2.33929  8.95367   24.59714  1.000 13.36433  ? 51  LEU A C    1 
ATOM   833  O O    . LEU A 1 59  ? -2.63685  7.95758   23.92721  1.000 12.07233  ? 51  LEU A O    1 
ATOM   834  C CB   . LEU A 1 59  ? -0.26840  9.63429   23.33862  1.000 11.99725  ? 51  LEU A CB   1 
ATOM   835  C CG   . LEU A 1 59  ? -1.00340  10.59186  22.40714  1.000 11.99050  ? 51  LEU A CG   1 
ATOM   836  C CD1  . LEU A 1 59  ? -1.06320  11.99088  23.04270  1.000 10.26635  ? 51  LEU A CD1  1 
ATOM   837  C CD2  . LEU A 1 59  ? -0.34976  10.67845  21.03817  1.000 16.19252  ? 51  LEU A CD2  1 
ATOM   838  H H    . LEU A 1 59  ? -0.08523  7.65952   25.06350  1.000 13.19029  ? 51  LEU A H    1 
ATOM   839  H HA   . LEU A 1 59  ? -0.87632  10.26257  25.18583  1.000 16.27507  ? 51  LEU A HA   1 
ATOM   840  H HB2  . LEU A 1 59  ? 0.62467   9.98996   23.46832  1.000 14.41372  ? 51  LEU A HB2  1 
ATOM   841  H HB3  . LEU A 1 59  ? -0.22168  8.77631   22.88851  1.000 14.41372  ? 51  LEU A HB3  1 
ATOM   842  H HG   . LEU A 1 59  ? -1.90212  10.25179  22.27464  1.000 14.40562  ? 51  LEU A HG   1 
ATOM   843  H HD11 . LEU A 1 59  ? -1.51147  12.59640  22.43172  1.000 12.33665  ? 51  LEU A HD11 1 
ATOM   844  H HD12 . LEU A 1 59  ? -1.55559  11.93805  23.87676  1.000 12.33665  ? 51  LEU A HD12 1 
ATOM   845  H HD13 . LEU A 1 59  ? -0.15937  12.30009  23.21118  1.000 12.33665  ? 51  LEU A HD13 1 
ATOM   846  H HD21 . LEU A 1 59  ? -0.88769  11.24865  20.46686  1.000 19.44805  ? 51  LEU A HD21 1 
ATOM   847  H HD22 . LEU A 1 59  ? 0.53969   11.05289  21.13602  1.000 19.44805  ? 51  LEU A HD22 1 
ATOM   848  H HD23 . LEU A 1 59  ? -0.29372  9.78778   20.65807  1.000 19.44805  ? 51  LEU A HD23 1 
ATOM   849  N N    . THR A 1 60  ? -3.24069  9.70036   25.21332  1.000 11.41518  ? 52  THR A N    1 
ATOM   850  C CA   . THR A 1 60  ? -4.60602  9.24216   25.37304  1.000 11.28929  ? 52  THR A CA   1 
ATOM   851  C C    . THR A 1 60  ? -5.56621  10.38414  25.09565  1.000 12.19025  ? 52  THR A C    1 
ATOM   852  O O    . THR A 1 60  ? -5.21175  11.56777  25.16183  1.000 12.48555  ? 52  THR A O    1 
ATOM   853  C CB   . THR A 1 60  ? -4.84975  8.68847   26.78569  1.000 17.15630  ? 52  THR A CB   1 
ATOM   854  O OG1  . THR A 1 60  ? -4.81247  9.76216   27.73371  1.000 12.92493  ? 52  THR A OG1  1 
ATOM   855  C CG2  . THR A 1 60  ? -3.79844  7.66256   27.15356  1.000 13.16523  ? 52  THR A CG2  1 
ATOM   856  H H    . THR A 1 60  ? -3.08409  10.47713  25.54753  1.000 13.71524  ? 52  THR A H    1 
ATOM   857  H HA   . THR A 1 60  ? -4.78100  8.54007   24.72701  1.000 13.56417  ? 52  THR A HA   1 
ATOM   858  H HB   . THR A 1 60  ? -5.71767  8.25623   26.81382  1.000 20.60458  ? 52  THR A HB   1 
ATOM   859  H HG1  . THR A 1 60  ? -4.03527  10.07742  27.78031  1.000 15.52694  ? 52  THR A HG1  1 
ATOM   860  H HG21 . THR A 1 60  ? -4.00376  7.27226   28.01751  1.000 15.81529  ? 52  THR A HG21 1 
ATOM   861  H HG22 . THR A 1 60  ? -3.77508  6.95792   26.48735  1.000 15.81529  ? 52  THR A HG22 1 
ATOM   862  H HG23 . THR A 1 60  ? -2.92551  8.08321   27.19761  1.000 15.81529  ? 52  THR A HG23 1 
ATOM   863  N N    . ASN A 1 61  ? -6.79879  10.00179  24.77485  1.000 16.77122  ? 53  ASN A N    1 
ATOM   864  C CA   . ASN A 1 61  ? -7.86641  10.94782  24.48585  1.000 14.20593  ? 53  ASN A CA   1 
ATOM   865  C C    . ASN A 1 61  ? -8.73484  11.18840  25.71838  1.000 19.22504  ? 53  ASN A C    1 
ATOM   866  O O    . ASN A 1 61  ? -8.79871  12.30711  26.23425  1.000 22.77351  ? 53  ASN A O    1 
ATOM   867  C CB   . ASN A 1 61  ? -8.70212  10.42761  23.30509  1.000 20.02689  ? 53  ASN A CB   1 
ATOM   868  C CG   . ASN A 1 61  ? -9.73013  11.43949  22.81869  1.000 28.85040  ? 53  ASN A CG   1 
ATOM   869  O OD1  . ASN A 1 61  ? -9.51012  12.64189  22.89113  1.000 28.50149  ? 53  ASN A OD1  1 
ATOM   870  N ND2  . ASN A 1 61  ? -10.85846 10.94887  22.31705  1.000 31.68723  ? 53  ASN A ND2  1 
ATOM   871  H H    . ASN A 1 61  ? -7.04513  9.17984   24.71723  1.000 20.14249  ? 53  ASN A H    1 
ATOM   872  H HA   . ASN A 1 61  ? -7.48844  11.80170  24.22329  1.000 17.06414  ? 53  ASN A HA   1 
ATOM   873  H HB2  . ASN A 1 61  ? -8.10976  10.22267  22.56482  1.000 24.04929  ? 53  ASN A HB2  1 
ATOM   874  H HB3  . ASN A 1 61  ? -9.17633  9.62793   23.58174  1.000 24.04929  ? 53  ASN A HB3  1 
ATOM   875  H HD21 . ASN A 1 61  ? -11.46889 11.48211  22.02958  1.000 38.04170  ? 53  ASN A HD21 1 
ATOM   876  H HD22 . ASN A 1 61  ? -10.97834 10.09808  22.27983  1.000 38.04170  ? 53  ASN A HD22 1 
ATOM   877  N N    . LYS A 1 62  ? -9.37275  10.14498  26.22917  1.000 20.93160  ? 54  LYS A N    1 
ATOM   878  C CA   . LYS A 1 62  ? -10.24922 10.26083  27.38524  1.000 21.46084  ? 54  LYS A CA   1 
ATOM   879  C C    . LYS A 1 62  ? -9.55778  9.75079   28.64140  1.000 18.50169  ? 54  LYS A C    1 
ATOM   880  O O    . LYS A 1 62  ? -8.84051  8.75066   28.60062  1.000 19.12184  ? 54  LYS A O    1 
ATOM   881  C CB   . LYS A 1 62  ? -11.53904 9.46548   27.16165  1.000 27.31352  ? 54  LYS A CB   1 
ATOM   882  C CG   . LYS A 1 62  ? -12.40897 9.98164   26.02174  1.000 28.57987  ? 54  LYS A CG   1 
ATOM   883  C CD   . LYS A 1 62  ? -12.83903 11.40974  26.28870  1.000 33.23159  ? 54  LYS A CD   1 
ATOM   884  C CE   . LYS A 1 62  ? -13.93688 11.84710  25.33585  1.000 39.61683  ? 54  LYS A CE   1 
ATOM   885  N NZ   . LYS A 1 62  ? -14.11492 13.32585  25.36425  1.000 64.16543  ? 54  LYS A NZ   1 
ATOM   886  H H    . LYS A 1 62  ? -9.31290  9.34543   25.91814  1.000 25.13494  ? 54  LYS A H    1 
ATOM   887  H HA   . LYS A 1 62  ? -10.46921 11.19583  27.52042  1.000 25.77003  ? 54  LYS A HA   1 
ATOM   888  H HB2  . LYS A 1 62  ? -11.30421 8.54657   26.95829  1.000 32.79325  ? 54  LYS A HB2  1 
ATOM   889  H HB3  . LYS A 1 62  ? -12.06854 9.50068   27.97362  1.000 32.79325  ? 54  LYS A HB3  1 
ATOM   890  H HG2  . LYS A 1 62  ? -11.90553 9.96009   25.19290  1.000 34.31287  ? 54  LYS A HG2  1 
ATOM   891  H HG3  . LYS A 1 62  ? -13.20248 9.42942   25.94239  1.000 34.31287  ? 54  LYS A HG3  1 
ATOM   892  H HD2  . LYS A 1 62  ? -13.17653 11.47957  27.19540  1.000 39.89493  ? 54  LYS A HD2  1 
ATOM   893  H HD3  . LYS A 1 62  ? -12.07947 12.00144  26.17094  1.000 39.89493  ? 54  LYS A HD3  1 
ATOM   894  H HE2  . LYS A 1 62  ? -13.70332 11.58371  24.43198  1.000 47.55722  ? 54  LYS A HE2  1 
ATOM   895  H HE3  . LYS A 1 62  ? -14.77418 11.43242  25.59636  1.000 47.55722  ? 54  LYS A HE3  1 
ATOM   896  H HZ1  . LYS A 1 62  ? -14.67512 13.57743  24.72006  1.000 77.01553  ? 54  LYS A HZ1  1 
ATOM   897  H HZ2  . LYS A 1 62  ? -14.44733 13.57738  26.15059  1.000 77.01553  ? 54  LYS A HZ2  1 
ATOM   898  H HZ3  . LYS A 1 62  ? -13.33145 13.72923  25.23952  1.000 77.01553  ? 54  LYS A HZ3  1 
ATOM   899  N N    . ASN A 1 63  ? -9.80045  10.43307  29.76225  1.000 17.24204  ? 55  ASN A N    1 
ATOM   900  C CA   . ASN A 1 63  ? -9.40137  9.95534   31.08509  1.000 16.97832  ? 55  ASN A CA   1 
ATOM   901  C C    . ASN A 1 63  ? -10.42463 8.92233   31.56495  1.000 14.64865  ? 55  ASN A C    1 
ATOM   902  O O    . ASN A 1 63  ? -11.06682 9.06452   32.60120  1.000 23.68520  ? 55  ASN A O    1 
ATOM   903  C CB   . ASN A 1 63  ? -9.28167  11.12973  32.04627  1.000 18.03915  ? 55  ASN A CB   1 
ATOM   904  C CG   . ASN A 1 63  ? -8.56052  10.76835  33.33006  1.000 18.70888  ? 55  ASN A CG   1 
ATOM   905  O OD1  . ASN A 1 63  ? -7.73159  9.83766   33.37365  1.000 17.46205  ? 55  ASN A OD1  1 
ATOM   906  N ND2  . ASN A 1 63  ? -8.86835  11.50240  34.38861  1.000 19.84990  ? 55  ASN A ND2  1 
ATOM   907  H H    . ASN A 1 63  ? -10.20396 11.19228  29.78188  1.000 20.70747  ? 55  ASN A H    1 
ATOM   908  H HA   . ASN A 1 63  ? -8.53029  9.53096   31.04011  1.000 20.39100  ? 55  ASN A HA   1 
ATOM   909  H HB2  . ASN A 1 63  ? -8.78514  11.84217  31.61409  1.000 21.66400  ? 55  ASN A HB2  1 
ATOM   910  H HB3  . ASN A 1 63  ? -10.17103 11.43912  32.27913  1.000 21.66400  ? 55  ASN A HB3  1 
ATOM   911  H HD21 . ASN A 1 63  ? -8.49165  11.34476  35.14547  1.000 23.83690  ? 55  ASN A HD21 1 
ATOM   912  H HD22 . ASN A 1 63  ? -9.44493  12.13669  34.31910  1.000 23.83690  ? 55  ASN A HD22 1 
ATOM   913  N N    . ARG A 1 64  ? -10.54074 7.85936   30.77133  1.000 18.96243  ? 56  ARG A N    1 
ATOM   914  C CA   . ARG A 1 64  ? -11.60104 6.87267   30.92945  1.000 24.21762  ? 56  ARG A CA   1 
ATOM   915  C C    . ARG A 1 64  ? -11.53671 6.18115   32.28500  1.000 23.87704  ? 56  ARG A C    1 
ATOM   916  O O    . ARG A 1 64  ? -10.46973 6.02264   32.88058  1.000 20.26527  ? 56  ARG A O    1 
ATOM   917  C CB   . ARG A 1 64  ? -11.48309 5.81649   29.83232  1.000 23.13347  ? 56  ARG A CB   1 
ATOM   918  C CG   . ARG A 1 64  ? -10.07038 5.21788   29.75446  1.000 49.92034  ? 56  ARG A CG   1 
ATOM   919  C CD   . ARG A 1 64  ? -10.06573 3.78205   29.24714  1.000 47.54414  ? 56  ARG A CD   1 
ATOM   920  N NE   . ARG A 1 64  ? -10.36147 3.72262   27.82314  1.000 55.42366  ? 56  ARG A NE   1 
ATOM   921  C CZ   . ARG A 1 64  ? -11.42486 3.11849   27.30525  1.000 82.45447  ? 56  ARG A CZ   1 
ATOM   922  N NH1  . ARG A 1 64  ? -11.61038 3.12496   25.99368  1.000 70.29628  ? 56  ARG A NH1  1 
ATOM   923  N NH2  . ARG A 1 64  ? -12.30272 2.50260   28.09184  1.000 63.49365  ? 56  ARG A NH2  1 
ATOM   924  H H    . ARG A 1 64  ? -10.00657 7.68393   30.12057  1.000 22.77194  ? 56  ARG A H    1 
ATOM   925  H HA   . ARG A 1 64  ? -12.45670 7.32506   30.86556  1.000 29.07816  ? 56  ARG A HA   1 
ATOM   926  H HB2  . ARG A 1 64  ? -12.10741 5.09696   30.01509  1.000 27.77718  ? 56  ARG A HB2  1 
ATOM   927  H HB3  . ARG A 1 64  ? -11.68738 6.22342   28.97583  1.000 27.77718  ? 56  ARG A HB3  1 
ATOM   928  H HG2  . ARG A 1 64  ? -9.53357  5.75154   29.14788  1.000 59.92143  ? 56  ARG A HG2  1 
ATOM   929  H HG3  . ARG A 1 64  ? -9.67493  5.22382   30.64017  1.000 59.92143  ? 56  ARG A HG3  1 
ATOM   930  H HD2  . ARG A 1 64  ? -9.18998  3.39173   29.39410  1.000 57.06999  ? 56  ARG A HD2  1 
ATOM   931  H HD3  . ARG A 1 64  ? -10.74044 3.27117   29.72113  1.000 57.06999  ? 56  ARG A HD3  1 
ATOM   932  H HE   . ARG A 1 64  ? -9.81203  4.10338   27.28208  1.000 66.52541  ? 56  ARG A HE   1 
ATOM   933  H HH11 . ARG A 1 64  ? -11.04344 3.51929   25.48115  1.000 84.37256  ? 56  ARG A HH11 1 
ATOM   934  H HH12 . ARG A 1 64  ? -12.29775 2.73483   25.65469  1.000 84.37256  ? 56  ARG A HH12 1 
ATOM   935  H HH21 . ARG A 1 64  ? -12.18437 2.49322   28.94360  1.000 76.20940  ? 56  ARG A HH21 1 
ATOM   936  H HH22 . ARG A 1 64  ? -12.98876 2.11372   27.74872  1.000 76.20940  ? 56  ARG A HH22 1 
ATOM   937  N N    . ASN A 1 65  ? -12.69523 5.71783   32.74696  1.000 25.64711  ? 57  ASN A N    1 
ATOM   938  C CA   . ASN A 1 65  ? -12.73430 4.87516   33.92982  1.000 27.86807  ? 57  ASN A CA   1 
ATOM   939  C C    . ASN A 1 65  ? -12.10726 3.51820   33.63000  1.000 17.55036  ? 57  ASN A C    1 
ATOM   940  O O    . ASN A 1 65  ? -12.24305 2.97323   32.53193  1.000 21.26845  ? 57  ASN A O    1 
ATOM   941  C CB   . ASN A 1 65  ? -14.17422 4.68881   34.40380  1.000 33.31146  ? 57  ASN A CB   1 
ATOM   942  C CG   . ASN A 1 65  ? -14.73743 5.93204   35.05229  1.000 29.91081  ? 57  ASN A CG   1 
ATOM   943  O OD1  . ASN A 1 65  ? -13.99353 6.79192   35.53503  1.000 34.59596  ? 57  ASN A OD1  1 
ATOM   944  N ND2  . ASN A 1 65  ? -16.06239 6.03216   35.07689  1.000 44.97367  ? 57  ASN A ND2  1 
ATOM   945  H H    . ASN A 1 65  ? -13.46354 5.87706   32.39491  1.000 30.79355  ? 57  ASN A H    1 
ATOM   946  H HA   . ASN A 1 65  ? -12.23431 5.29539   34.64698  1.000 33.45870  ? 57  ASN A HA   1 
ATOM   947  H HB2  . ASN A 1 65  ? -14.73240 4.46799   33.64185  1.000 39.99077  ? 57  ASN A HB2  1 
ATOM   948  H HB3  . ASN A 1 65  ? -14.20281 3.97066   35.05521  1.000 39.99077  ? 57  ASN A HB3  1 
ATOM   949  H HD21 . ASN A 1 65  ? -16.54710 5.40924   34.73540  1.000 53.98543  ? 57  ASN A HD21 1 
ATOM   950  H HD22 . ASN A 1 65  ? -16.43508 6.71988   35.43430  1.000 53.98543  ? 57  ASN A HD22 1 
ATOM   951  N N    . VAL A 1 66  ? -11.44286 2.95883   34.63597  1.000 17.93570  ? 58  VAL A N    1 
ATOM   952  C CA   . VAL A 1 66  ? -10.77830 1.66454   34.52686  1.000 20.43015  ? 58  VAL A CA   1 
ATOM   953  C C    . VAL A 1 66  ? -11.21909 0.81661   35.70798  1.000 22.15727  ? 58  VAL A C    1 
ATOM   954  O O    . VAL A 1 66  ? -11.04538 1.22627   36.86152  1.000 21.62644  ? 58  VAL A O    1 
ATOM   955  C CB   . VAL A 1 66  ? -9.24767  1.79504   34.51439  1.000 20.78573  ? 58  VAL A CB   1 
ATOM   956  C CG1  . VAL A 1 66  ? -8.61051  0.40509   34.44344  1.000 22.87583  ? 58  VAL A CG1  1 
ATOM   957  C CG2  . VAL A 1 66  ? -8.79714  2.66564   33.35076  1.000 22.34322  ? 58  VAL A CG2  1 
ATOM   958  H H    . VAL A 1 66  ? -11.36102 3.31973   35.41228  1.000 21.53986  ? 58  VAL A H    1 
ATOM   959  H HA   . VAL A 1 66  ? -11.05753 1.23169   33.70493  1.000 24.53320  ? 58  VAL A HA   1 
ATOM   960  H HB   . VAL A 1 66  ? -8.95149  2.22426   35.33228  1.000 24.95990  ? 58  VAL A HB   1 
ATOM   961  H HG11 . VAL A 1 66  ? -7.69708  0.49209   34.12883  1.000 27.46802  ? 58  VAL A HG11 1 
ATOM   962  H HG12 . VAL A 1 66  ? -8.61914  0.00818   35.32848  1.000 27.46802  ? 58  VAL A HG12 1 
ATOM   963  H HG13 . VAL A 1 66  ? -9.12095  -0.14531  33.82910  1.000 27.46802  ? 58  VAL A HG13 1 
ATOM   964  H HG21 . VAL A 1 66  ? -7.82777  2.66960   33.31612  1.000 26.82889  ? 58  VAL A HG21 1 
ATOM   965  H HG22 . VAL A 1 66  ? -9.15610  2.30154   32.52645  1.000 26.82889  ? 58  VAL A HG22 1 
ATOM   966  H HG23 . VAL A 1 66  ? -9.12702  3.56787   33.48513  1.000 26.82889  ? 58  VAL A HG23 1 
ATOM   967  N N    . ARG A 1 67  ? -11.79553 -0.35294  35.42082  1.000 27.65953  ? 59  ARG A N    1 
ATOM   968  C CA   . ARG A 1 67  ? -12.21246 -1.28868  36.45994  1.000 28.95852  ? 59  ARG A CA   1 
ATOM   969  C C    . ARG A 1 67  ? -11.00294 -2.05085  36.98247  1.000 25.35920  ? 59  ARG A C    1 
ATOM   970  O O    . ARG A 1 67  ? -10.28972 -2.69570  36.20869  1.000 33.72109  ? 59  ARG A O    1 
ATOM   971  C CB   . ARG A 1 67  ? -13.24057 -2.27449  35.91431  1.000 34.11289  ? 59  ARG A CB   1 
ATOM   972  C CG   . ARG A 1 67  ? -14.63840 -1.72533  35.75512  1.000 56.20427  ? 59  ARG A CG   1 
ATOM   973  C CD   . ARG A 1 67  ? -15.59244 -2.83655  35.32783  1.000 58.12242  ? 59  ARG A CD   1 
ATOM   974  N NE   . ARG A 1 67  ? -16.64723 -2.34077  34.45004  1.000 63.87826  ? 59  ARG A NE   1 
ATOM   975  C CZ   . ARG A 1 67  ? -17.72981 -1.69914  34.87668  1.000 41.20949  ? 59  ARG A CZ   1 
ATOM   976  N NH1  . ARG A 1 67  ? -17.90174 -1.47715  36.17119  1.000 50.39768  ? 59  ARG A NH1  1 
ATOM   977  N NH2  . ARG A 1 67  ? -18.64139 -1.28023  34.01076  1.000 57.55411  ? 59  ARG A NH2  1 
ATOM   978  H H    . ARG A 1 67  ? -11.95669 -0.62819  34.62215  1.000 33.20846  ? 59  ARG A H    1 
ATOM   979  H HA   . ARG A 1 67  ? -12.61202 -0.78692  37.18759  1.000 34.76724  ? 59  ARG A HA   1 
ATOM   980  H HB2  . ARG A 1 67  ? -12.94490 -2.57226  35.03978  1.000 40.95249  ? 59  ARG A HB2  1 
ATOM   981  H HB3  . ARG A 1 67  ? -13.29314 -3.02915  36.52146  1.000 40.95249  ? 59  ARG A HB3  1 
ATOM   982  H HG2  . ARG A 1 67  ? -14.94444 -1.36092  36.60037  1.000 67.46215  ? 59  ARG A HG2  1 
ATOM   983  H HG3  . ARG A 1 67  ? -14.64221 -1.03383  35.07489  1.000 67.46215  ? 59  ARG A HG3  1 
ATOM   984  H HD2  . ARG A 1 67  ? -15.09514 -3.51828  34.84946  1.000 69.76393  ? 59  ARG A HD2  1 
ATOM   985  H HD3  . ARG A 1 67  ? -16.00868 -3.22070  36.11528  1.000 69.76393  ? 59  ARG A HD3  1 
ATOM   986  H HE   . ARG A 1 67  ? -16.56308 -2.47192  33.60428  1.000 76.67093  ? 59  ARG A HE   1 
ATOM   987  H HH11 . ARG A 1 67  ? -17.31258 -1.74833  36.73595  1.000 60.49424  ? 59  ARG A HH11 1 
ATOM   988  H HH12 . ARG A 1 67  ? -18.60253 -1.06184  36.44690  1.000 60.49424  ? 59  ARG A HH12 1 
ATOM   989  H HH21 . ARG A 1 67  ? -18.53334 -1.42337  33.16967  1.000 69.08196  ? 59  ARG A HH21 1 
ATOM   990  H HH22 . ARG A 1 67  ? -19.34100 -0.86524  34.28992  1.000 69.08196  ? 59  ARG A HH22 1 
ATOM   991  N N    . THR A 1 68  ? -10.77051 -1.97324  38.28552  1.000 22.36185  ? 60  THR A N    1 
ATOM   992  C CA   . THR A 1 68  ? -9.72604  -2.72532  38.96293  1.000 30.04203  ? 60  THR A CA   1 
ATOM   993  C C    . THR A 1 68  ? -10.35114 -3.62032  40.02800  1.000 42.41060  ? 60  THR A C    1 
ATOM   994  O O    . THR A 1 68  ? -11.54860 -3.54532  40.32091  1.000 28.57203  ? 60  THR A O    1 
ATOM   995  C CB   . THR A 1 68  ? -8.69629  -1.79050  39.60952  1.000 31.86987  ? 60  THR A CB   1 
ATOM   996  O OG1  . THR A 1 68  ? -9.24516  -1.22983  40.80880  1.000 31.14414  ? 60  THR A OG1  1 
ATOM   997  C CG2  . THR A 1 68  ? -8.30663  -0.67399  38.64537  1.000 36.32144  ? 60  THR A CG2  1 
ATOM   998  H H    . THR A 1 68  ? -11.22279 -1.47196  38.81821  1.000 26.85125  ? 60  THR A H    1 
ATOM   999  H HA   . THR A 1 68  ? -9.26669  -3.28277  38.31552  1.000 36.06746  ? 60  THR A HA   1 
ATOM   1000 H HB   . THR A 1 68  ? -7.89418  -2.28959  39.82959  1.000 38.26087  ? 60  THR A HB   1 
ATOM   1001 H HG1  . THR A 1 68  ? -8.67936  -0.73034  41.17755  1.000 37.38999  ? 60  THR A HG1  1 
ATOM   1002 H HG21 . THR A 1 68  ? -7.62849  -0.10941  39.04822  1.000 43.60275  ? 60  THR A HG21 1 
ATOM   1003 H HG22 . THR A 1 68  ? -7.95435  -1.05232  37.82460  1.000 43.60275  ? 60  THR A HG22 1 
ATOM   1004 H HG23 . THR A 1 68  ? -9.08286  -0.13191  38.43438  1.000 43.60275  ? 60  THR A HG23 1 
ATOM   1005 N N    . HIS A 1 69  ? -9.51645  -4.47401  40.62302  1.000 41.22586  ? 61  HIS A N    1 
ATOM   1006 C CA   . HIS A 1 69  ? -9.99814  -5.33291  41.69949  1.000 46.65132  ? 61  HIS A CA   1 
ATOM   1007 C C    . HIS A 1 69  ? -10.48558 -4.50792  42.88383  1.000 40.09354  ? 61  HIS A C    1 
ATOM   1008 O O    . HIS A 1 69  ? -11.45779 -4.88112  43.54971  1.000 33.68112  ? 61  HIS A O    1 
ATOM   1009 C CB   . HIS A 1 69  ? -8.89599  -6.29448  42.14364  1.000 44.51305  ? 61  HIS A CB   1 
ATOM   1010 C CG   . HIS A 1 69  ? -9.29826  -7.19132  43.27425  1.000 60.13735  ? 61  HIS A CG   1 
ATOM   1011 N ND1  . HIS A 1 69  ? -10.41330 -8.00034  43.22118  1.000 56.11659  ? 61  HIS A ND1  1 
ATOM   1012 C CD2  . HIS A 1 69  ? -8.73589  -7.40582  44.48758  1.000 53.40172  ? 61  HIS A CD2  1 
ATOM   1013 C CE1  . HIS A 1 69  ? -10.52058 -8.67444  44.35239  1.000 42.92209  ? 61  HIS A CE1  1 
ATOM   1014 N NE2  . HIS A 1 69  ? -9.51488  -8.33284  45.13757  1.000 44.26327  ? 61  HIS A NE2  1 
ATOM   1015 H H    . HIS A 1 69  ? -8.68519  -4.57228  40.42568  1.000 49.48805  ? 61  HIS A H    1 
ATOM   1016 H HA   . HIS A 1 69  ? -10.74133 -5.85950  41.36590  1.000 55.99861  ? 61  HIS A HA   1 
ATOM   1017 H HB2  . HIS A 1 69  ? -8.65104  -6.85683  41.39220  1.000 53.43268  ? 61  HIS A HB2  1 
ATOM   1018 H HB3  . HIS A 1 69  ? -8.12893  -5.77691  42.43460  1.000 53.43268  ? 61  HIS A HB3  1 
ATOM   1019 H HD2  . HIS A 1 69  ? -7.96667  -7.00150  44.81882  1.000 64.09909  ? 61  HIS A HD2  1 
ATOM   1020 H HE1  . HIS A 1 69  ? -11.19017 -9.28541  44.56039  1.000 51.52354  ? 61  HIS A HE1  1 
ATOM   1021 N N    . ASP A 1 70  ? -9.82035  -3.38444  43.16479  1.000 49.13595  ? 62  ASP A N    1 
ATOM   1022 C CA   . ASP A 1 70  ? -10.18375 -2.53817  44.29566  1.000 51.20261  ? 62  ASP A CA   1 
ATOM   1023 C C    . ASP A 1 70  ? -11.35751 -1.61347  43.99633  1.000 60.50856  ? 62  ASP A C    1 
ATOM   1024 O O    . ASP A 1 70  ? -11.92187 -1.03291  44.93147  1.000 65.14894  ? 62  ASP A O    1 
ATOM   1025 C CB   . ASP A 1 70  ? -8.98038  -1.69519  44.73249  1.000 62.85897  ? 62  ASP A CB   1 
ATOM   1026 C CG   . ASP A 1 70  ? -7.91498  -2.51384  45.44102  1.000 75.10133  ? 62  ASP A CG   1 
ATOM   1027 O OD1  . ASP A 1 70  ? -7.92452  -3.75454  45.29814  1.000 61.30842  ? 62  ASP A OD1  1 
ATOM   1028 O OD2  . ASP A 1 70  ? -7.06697  -1.91517  46.13960  1.000 76.04637  ? 62  ASP A OD2  1 
ATOM   1029 H H    . ASP A 1 70  ? -9.15117  -3.09152  42.71092  1.000 58.98017  ? 62  ASP A H    1 
ATOM   1030 H HA   . ASP A 1 70  ? -10.43577 -3.11211  45.03591  1.000 61.46016  ? 62  ASP A HA   1 
ATOM   1031 H HB2  . ASP A 1 70  ? -8.57623  -1.29131  43.94863  1.000 75.44779  ? 62  ASP A HB2  1 
ATOM   1032 H HB3  . ASP A 1 70  ? -9.28311  -1.00465  45.34274  1.000 75.44779  ? 62  ASP A HB3  1 
ATOM   1033 N N    . GLY A 1 71  ? -11.74023 -1.46811  42.73439  1.000 39.65913  ? 63  GLY A N    1 
ATOM   1034 C CA   . GLY A 1 71  ? -12.80583 -0.57849  42.33362  1.000 43.80703  ? 63  GLY A CA   1 
ATOM   1035 C C    . GLY A 1 71  ? -12.43136 0.15855   41.06428  1.000 40.31866  ? 63  GLY A C    1 
ATOM   1036 O O    . GLY A 1 71  ? -11.42976 -0.14023  40.41629  1.000 32.47209  ? 63  GLY A O    1 
ATOM   1037 H H    . GLY A 1 71  ? -11.38267 -1.89016  42.07589  1.000 47.60797  ? 63  GLY A H    1 
ATOM   1038 H HA2  . GLY A 1 71  ? -13.61615 -1.08696  42.17313  1.000 52.58545  ? 63  GLY A HA2  1 
ATOM   1039 H HA3  . GLY A 1 71  ? -12.97388 0.07049   43.03468  1.000 52.58545  ? 63  GLY A HA3  1 
ATOM   1040 N N    . ILE A 1 72  ? -13.24493 1.14154   40.70307  1.000 34.28962  ? 64  ILE A N    1 
ATOM   1041 C CA   . ILE A 1 72  ? -13.01755 1.90947   39.48446  1.000 26.59346  ? 64  ILE A CA   1 
ATOM   1042 C C    . ILE A 1 72  ? -12.13648 3.10632   39.80366  1.000 27.58010  ? 64  ILE A C    1 
ATOM   1043 O O    . ILE A 1 72  ? -12.28544 3.75714   40.84380  1.000 28.43265  ? 64  ILE A O    1 
ATOM   1044 C CB   . ILE A 1 72  ? -14.34737 2.34888   38.84597  1.000 34.77664  ? 64  ILE A CB   1 
ATOM   1045 C CG1  . ILE A 1 72  ? -15.14621 1.12053   38.41351  1.000 46.49445  ? 64  ILE A CG1  1 
ATOM   1046 C CG2  . ILE A 1 72  ? -14.08610 3.25018   37.66235  1.000 28.84959  ? 64  ILE A CG2  1 
ATOM   1047 C CD1  . ILE A 1 72  ? -16.52499 1.43619   37.88338  1.000 41.80061  ? 64  ILE A CD1  1 
ATOM   1048 H H    . ILE A 1 72  ? -13.93912 1.38459   41.14876  1.000 41.16456  ? 64  ILE A H    1 
ATOM   1049 H HA   . ILE A 1 72  ? -12.54978 1.34814   38.84650  1.000 31.92917  ? 64  ILE A HA   1 
ATOM   1050 H HB   . ILE A 1 72  ? -14.86217 2.84282   39.50316  1.000 41.74899  ? 64  ILE A HB   1 
ATOM   1051 H HG12 . ILE A 1 72  ? -14.65777 0.66418   37.71061  1.000 55.81037  ? 64  ILE A HG12 1 
ATOM   1052 H HG13 . ILE A 1 72  ? -15.25208 0.53383   39.17867  1.000 55.81037  ? 64  ILE A HG13 1 
ATOM   1053 H HG21 . ILE A 1 72  ? -14.93393 3.50250   37.26432  1.000 34.63654  ? 64  ILE A HG21 1 
ATOM   1054 H HG22 . ILE A 1 72  ? -13.61471 4.04166   37.96608  1.000 34.63654  ? 64  ILE A HG22 1 
ATOM   1055 H HG23 . ILE A 1 72  ? -13.54579 2.77171   37.01425  1.000 34.63654  ? 64  ILE A HG23 1 
ATOM   1056 H HD11 . ILE A 1 72  ? -16.96922 0.60737   37.64543  1.000 50.17775  ? 64  ILE A HD11 1 
ATOM   1057 H HD12 . ILE A 1 72  ? -17.03023 1.89650   38.57167  1.000 50.17775  ? 64  ILE A HD12 1 
ATOM   1058 H HD13 . ILE A 1 72  ? -16.44029 2.00267   37.10055  1.000 50.17775  ? 64  ILE A HD13 1 
ATOM   1059 N N    . VAL A 1 73  ? -11.19866 3.38949   38.90265  1.000 27.40300  ? 65  VAL A N    1 
ATOM   1060 C CA   . VAL A 1 73  ? -10.31131 4.53819   39.01001  1.000 20.42763  ? 65  VAL A CA   1 
ATOM   1061 C C    . VAL A 1 73  ? -10.25321 5.20645   37.64322  1.000 19.83389  ? 65  VAL A C    1 
ATOM   1062 O O    . VAL A 1 73  ? -10.67606 4.64115   36.63174  1.000 19.45249  ? 65  VAL A O    1 
ATOM   1063 C CB   . VAL A 1 73  ? -8.89828  4.14038   39.48409  1.000 19.73752  ? 65  VAL A CB   1 
ATOM   1064 C CG1  . VAL A 1 73  ? -8.95588  3.48735   40.86313  1.000 24.90552  ? 65  VAL A CG1  1 
ATOM   1065 C CG2  . VAL A 1 73  ? -8.24550  3.20325   38.48374  1.000 18.68127  ? 65  VAL A CG2  1 
ATOM   1066 H H    . VAL A 1 73  ? -11.05531 2.91457   38.20015  1.000 32.90062  ? 65  VAL A H    1 
ATOM   1067 H HA   . VAL A 1 73  ? -10.66963 5.17329   39.64965  1.000 24.53018  ? 65  VAL A HA   1 
ATOM   1068 H HB   . VAL A 1 73  ? -8.35690  4.94249   39.55065  1.000 23.70204  ? 65  VAL A HB   1 
ATOM   1069 H HG11 . VAL A 1 73  ? -8.05764  3.24022   41.13329  1.000 29.90364  ? 65  VAL A HG11 1 
ATOM   1070 H HG12 . VAL A 1 73  ? -9.32965  4.11970   41.49663  1.000 29.90364  ? 65  VAL A HG12 1 
ATOM   1071 H HG13 . VAL A 1 73  ? -9.51610  2.69694   40.81510  1.000 29.90364  ? 65  VAL A HG13 1 
ATOM   1072 H HG21 . VAL A 1 73  ? -7.40332  2.88907   38.84833  1.000 22.43455  ? 65  VAL A HG21 1 
ATOM   1073 H HG22 . VAL A 1 73  ? -8.83709  2.45163   38.32253  1.000 22.43455  ? 65  VAL A HG22 1 
ATOM   1074 H HG23 . VAL A 1 73  ? -8.08874  3.68426   37.65612  1.000 22.43455  ? 65  VAL A HG23 1 
ATOM   1075 N N    . THR A 1 74  ? -9.71309  6.42202   37.61557  1.000 16.65280  ? 66  THR A N    1 
ATOM   1076 C CA   . THR A 1 74  ? -9.48215  7.06749   36.33641  1.000 17.42715  ? 66  THR A CA   1 
ATOM   1077 C C    . THR A 1 74  ? -8.22331  6.50303   35.67228  1.000 15.48988  ? 66  THR A C    1 
ATOM   1078 O O    . THR A 1 74  ? -7.33387  5.94636   36.31985  1.000 13.82609  ? 66  THR A O    1 
ATOM   1079 C CB   . THR A 1 74  ? -9.33584  8.58135   36.49762  1.000 21.05725  ? 66  THR A CB   1 
ATOM   1080 O OG1  . THR A 1 74  ? -8.07262  8.87630   37.09138  1.000 16.77441  ? 66  THR A OG1  1 
ATOM   1081 C CG2  . THR A 1 74  ? -10.46172 9.15169   37.38470  1.000 22.12781  ? 66  THR A CG2  1 
ATOM   1082 H H    . THR A 1 74  ? -9.47956  6.87787   38.30642  1.000 20.00039  ? 66  THR A H    1 
ATOM   1083 H HA   . THR A 1 74  ? -10.24461 6.89954   35.76078  1.000 20.92960  ? 66  THR A HA   1 
ATOM   1084 H HB   . THR A 1 74  ? -9.39454  9.00382   35.62643  1.000 25.28573  ? 66  THR A HB   1 
ATOM   1085 H HG1  . THR A 1 74  ? -7.98250  9.70702   37.17728  1.000 20.14632  ? 66  THR A HG1  1 
ATOM   1086 H HG21 . THR A 1 74  ? -10.38977 10.11788  37.43176  1.000 26.57040  ? 66  THR A HG21 1 
ATOM   1087 H HG22 . THR A 1 74  ? -11.32697 8.91816   37.01360  1.000 26.57040  ? 66  THR A HG22 1 
ATOM   1088 H HG23 . THR A 1 74  ? -10.39482 8.78701   38.28104  1.000 26.57040  ? 66  THR A HG23 1 
ATOM   1089 N N    . LEU A 1 75  ? -8.14836  6.68131   34.35580  1.000 17.89223  ? 67  LEU A N    1 
ATOM   1090 C CA   . LEU A 1 75  ? -6.98305  6.19658   33.62336  1.000 16.58761  ? 67  LEU A CA   1 
ATOM   1091 C C    . LEU A 1 75  ? -5.70287  6.83196   34.15234  1.000 15.05933  ? 67  LEU A C    1 
ATOM   1092 O O    . LEU A 1 75  ? -4.67713  6.16062   34.31113  1.000 14.16425  ? 67  LEU A O    1 
ATOM   1093 C CB   . LEU A 1 75  ? -7.16010  6.48180   32.13373  1.000 13.04024  ? 67  LEU A CB   1 
ATOM   1094 C CG   . LEU A 1 75  ? -6.03176  5.98315   31.21998  1.000 17.16706  ? 67  LEU A CG   1 
ATOM   1095 C CD1  . LEU A 1 75  ? -5.92853  4.46581   31.26326  1.000 16.66567  ? 67  LEU A CD1  1 
ATOM   1096 C CD2  . LEU A 1 75  ? -6.24456  6.46664   29.78428  1.000 19.44988  ? 67  LEU A CD2  1 
ATOM   1097 H H    . LEU A 1 75  ? -8.74453  7.07071   33.87356  1.000 21.48770  ? 67  LEU A H    1 
ATOM   1098 H HA   . LEU A 1 75  ? -6.90597  5.23646   33.73792  1.000 19.92215  ? 67  LEU A HA   1 
ATOM   1099 H HB2  . LEU A 1 75  ? -7.97974  6.05522   31.83857  1.000 15.66531  ? 67  LEU A HB2  1 
ATOM   1100 H HB3  . LEU A 1 75  ? -7.22438  7.44228   32.01437  1.000 15.66531  ? 67  LEU A HB3  1 
ATOM   1101 H HG   . LEU A 1 75  ? -5.19138  6.34782   31.53887  1.000 20.61750  ? 67  LEU A HG   1 
ATOM   1102 H HD11 . LEU A 1 75  ? -5.28655  4.17383   30.59730  1.000 20.01582  ? 67  LEU A HD11 1 
ATOM   1103 H HD12 . LEU A 1 75  ? -5.63501  4.19432   32.14703  1.000 20.01582  ? 67  LEU A HD12 1 
ATOM   1104 H HD13 . LEU A 1 75  ? -6.79975  4.08443   31.07241  1.000 20.01582  ? 67  LEU A HD13 1 
ATOM   1105 H HD21 . LEU A 1 75  ? -5.50439  6.16296   29.23581  1.000 23.35687  ? 67  LEU A HD21 1 
ATOM   1106 H HD22 . LEU A 1 75  ? -7.07748  6.10053   29.44795  1.000 23.35687  ? 67  LEU A HD22 1 
ATOM   1107 H HD23 . LEU A 1 75  ? -6.28361  7.43584   29.77996  1.000 23.35687  ? 67  LEU A HD23 1 
ATOM   1108 N N    . ASP A 1 76  ? -5.73006  8.13108   34.42306  1.000 12.91767  ? 68  ASP A N    1 
ATOM   1109 C CA   . ASP A 1 76  ? -4.53623  8.77369   34.95713  1.000 13.11732  ? 68  ASP A CA   1 
ATOM   1110 C C    . ASP A 1 76  ? -4.12514  8.15668   36.29037  1.000 17.90533  ? 68  ASP A C    1 
ATOM   1111 O O    . ASP A 1 76  ? -2.94520  7.86926   36.50843  1.000 15.28305  ? 68  ASP A O    1 
ATOM   1112 C CB   . ASP A 1 76  ? -4.77359  10.27352  35.10517  1.000 14.47826  ? 68  ASP A CB   1 
ATOM   1113 C CG   . ASP A 1 76  ? -3.49193  11.04737  35.32478  1.000 20.19741  ? 68  ASP A CG   1 
ATOM   1114 O OD1  . ASP A 1 76  ? -2.54750  10.86974  34.52646  1.000 16.15345  ? 68  ASP A OD1  1 
ATOM   1115 O OD2  . ASP A 1 76  ? -3.43168  11.84447  36.28781  1.000 24.79009  ? 68  ASP A OD2  1 
ATOM   1116 H H    . ASP A 1 76  ? -6.40703  8.64934   34.31027  1.000 15.51823  ? 68  ASP A H    1 
ATOM   1117 H HA   . ASP A 1 76  ? -3.80484  8.64653   34.33280  1.000 15.75781  ? 68  ASP A HA   1 
ATOM   1118 H HB2  . ASP A 1 76  ? -5.19235  10.60899  34.29708  1.000 17.39094  ? 68  ASP A HB2  1 
ATOM   1119 H HB3  . ASP A 1 76  ? -5.35257  10.42860  35.86781  1.000 17.39094  ? 68  ASP A HB3  1 
ATOM   1120 N N    . GLU A 1 77  ? -5.08705  7.90153   37.18157  1.000 14.81091  ? 69  GLU A N    1 
ATOM   1121 C CA   . GLU A 1 77  ? -4.74576  7.24950   38.44169  1.000 13.71230  ? 69  GLU A CA   1 
ATOM   1122 C C    . GLU A 1 77  ? -4.21290  5.84279   38.19911  1.000 12.82983  ? 69  GLU A C    1 
ATOM   1123 O O    . GLU A 1 77  ? -3.28099  5.39110   38.87765  1.000 18.24662  ? 69  GLU A O    1 
ATOM   1124 C CB   . GLU A 1 77  ? -5.97295  7.20278   39.35980  1.000 20.29323  ? 69  GLU A CB   1 
ATOM   1125 C CG   . GLU A 1 77  ? -6.50320  8.56976   39.78477  1.000 22.29990  ? 69  GLU A CG   1 
ATOM   1126 C CD   . GLU A 1 77  ? -7.85511  8.49189   40.50001  1.000 30.90642  ? 69  GLU A CD   1 
ATOM   1127 O OE1  . GLU A 1 77  ? -8.06995  9.29541   41.43300  1.000 46.19236  ? 69  GLU A OE1  1 
ATOM   1128 O OE2  . GLU A 1 77  ? -8.70686  7.63961   40.13479  1.000 25.56634  ? 69  GLU A OE2  1 
ATOM   1129 H H    . GLU A 1 77  ? -5.91996  8.09108   37.08186  1.000 17.79012  ? 69  GLU A H    1 
ATOM   1130 H HA   . GLU A 1 77  ? -4.05608  7.76658   38.88652  1.000 16.47178  ? 69  GLU A HA   1 
ATOM   1131 H HB2  . GLU A 1 77  ? -6.68912  6.74345   38.89395  1.000 24.36890  ? 69  GLU A HB2  1 
ATOM   1132 H HB3  . GLU A 1 77  ? -5.73664  6.71753   40.16577  1.000 24.36890  ? 69  GLU A HB3  1 
ATOM   1133 H HG2  . GLU A 1 77  ? -5.86720  8.97962   40.39174  1.000 26.77690  ? 69  GLU A HG2  1 
ATOM   1134 H HG3  . GLU A 1 77  ? -6.61378  9.12384   38.99631  1.000 26.77690  ? 69  GLU A HG3  1 
ATOM   1135 N N    . TYR A 1 78  ? -4.83181  5.11486   37.26960  1.000 15.42925  ? 70  TYR A N    1 
ATOM   1136 C CA   . TYR A 1 78  ? -4.39631  3.75615   36.98345  1.000 12.45590  ? 70  TYR A CA   1 
ATOM   1137 C C    . TYR A 1 78  ? -2.95879  3.74391   36.49464  1.000 18.05153  ? 70  TYR A C    1 
ATOM   1138 O O    . TYR A 1 78  ? -2.12219  2.98065   36.99018  1.000 16.08441  ? 70  TYR A O    1 
ATOM   1139 C CB   . TYR A 1 78  ? -5.31561  3.13384   35.94048  1.000 13.63125  ? 70  TYR A CB   1 
ATOM   1140 C CG   . TYR A 1 78  ? -4.90601  1.76959   35.49350  1.000 16.83470  ? 70  TYR A CG   1 
ATOM   1141 C CD1  . TYR A 1 78  ? -5.30487  0.64037   36.20145  1.000 18.60820  ? 70  TYR A CD1  1 
ATOM   1142 C CD2  . TYR A 1 78  ? -4.12456  1.59508   34.35737  1.000 14.62343  ? 70  TYR A CD2  1 
ATOM   1143 C CE1  . TYR A 1 78  ? -4.94185  -0.61281  35.79061  1.000 16.05325  ? 70  TYR A CE1  1 
ATOM   1144 C CE2  . TYR A 1 78  ? -3.75465  0.31643   33.93850  1.000 16.57060  ? 70  TYR A CE2  1 
ATOM   1145 C CZ   . TYR A 1 78  ? -4.15772  -0.77172  34.66900  1.000 23.99034  ? 70  TYR A CZ   1 
ATOM   1146 O OH   . TYR A 1 78  ? -3.78363  -2.03661  34.27918  1.000 23.50797  ? 70  TYR A OH   1 
ATOM   1147 H H    . TYR A 1 78  ? -5.49849  5.38365   36.79748  1.000 18.53213  ? 70  TYR A H    1 
ATOM   1148 H HA   . TYR A 1 78  ? -4.44849  3.22693   37.79469  1.000 14.96410  ? 70  TYR A HA   1 
ATOM   1149 H HB2  . TYR A 1 78  ? -6.20725  3.06418   36.31602  1.000 16.37453  ? 70  TYR A HB2  1 
ATOM   1150 H HB3  . TYR A 1 78  ? -5.32896  3.70722   35.15820  1.000 16.37453  ? 70  TYR A HB3  1 
ATOM   1151 H HD1  . TYR A 1 78  ? -5.82605  0.73898   36.96536  1.000 22.34686  ? 70  TYR A HD1  1 
ATOM   1152 H HD2  . TYR A 1 78  ? -3.84558  2.33753   33.87174  1.000 17.56514  ? 70  TYR A HD2  1 
ATOM   1153 H HE1  . TYR A 1 78  ? -5.22469  -1.35850  36.26899  1.000 19.28093  ? 70  TYR A HE1  1 
ATOM   1154 H HE2  . TYR A 1 78  ? -3.24021  0.20349   33.17202  1.000 19.90175  ? 70  TYR A HE2  1 
ATOM   1155 H HH   . TYR A 1 78  ? -3.35539  -1.99995  33.55747  1.000 28.22658  ? 70  TYR A HH   1 
ATOM   1156 N N    . LEU A 1 79  ? -2.65407  4.59727   35.52199  1.000 13.59372  ? 71  LEU A N    1 
ATOM   1157 C CA   . LEU A 1 79  ? -1.32524  4.58065   34.92517  1.000 13.28786  ? 71  LEU A CA   1 
ATOM   1158 C C    . LEU A 1 79  ? -0.26843  5.02947   35.92083  1.000 16.10425  ? 71  LEU A C    1 
ATOM   1159 O O    . LEU A 1 79  ? 0.82307   4.45088   35.98301  1.000 18.21205  ? 71  LEU A O    1 
ATOM   1160 C CB   . LEU A 1 79  ? -1.29391  5.47427   33.68602  1.000 13.76624  ? 71  LEU A CB   1 
ATOM   1161 C CG   . LEU A 1 79  ? -2.16992  5.02693   32.52139  1.000 17.84450  ? 71  LEU A CG   1 
ATOM   1162 C CD1  . LEU A 1 79  ? -2.22532  6.09959   31.43852  1.000 13.59545  ? 71  LEU A CD1  1 
ATOM   1163 C CD2  . LEU A 1 79  ? -1.69062  3.69532   31.93969  1.000 16.78291  ? 71  LEU A CD2  1 
ATOM   1164 H H    . LEU A 1 79  ? -3.18928  5.18574   35.19511  1.000 16.32948  ? 71  LEU A H    1 
ATOM   1165 H HA   . LEU A 1 79  ? -1.12097  3.67288   34.65110  1.000 15.96246  ? 71  LEU A HA   1 
ATOM   1166 H HB2  . LEU A 1 79  ? -1.58967  6.36117   33.94455  1.000 16.53651  ? 71  LEU A HB2  1 
ATOM   1167 H HB3  . LEU A 1 79  ? -0.38045  5.51058   33.36171  1.000 16.53651  ? 71  LEU A HB3  1 
ATOM   1168 H HG   . LEU A 1 79  ? -3.07028  4.89099   32.85572  1.000 21.43042  ? 71  LEU A HG   1 
ATOM   1169 H HD11 . LEU A 1 79  ? -2.79898  5.79268   30.71906  1.000 16.33156  ? 71  LEU A HD11 1 
ATOM   1170 H HD12 . LEU A 1 79  ? -2.58261  6.91627   31.82098  1.000 16.33156  ? 71  LEU A HD12 1 
ATOM   1171 H HD13 . LEU A 1 79  ? -1.32880  6.25610   31.10289  1.000 16.33156  ? 71  LEU A HD13 1 
ATOM   1172 H HD21 . LEU A 1 79  ? -2.23121  3.47645   31.16460  1.000 20.15652  ? 71  LEU A HD21 1 
ATOM   1173 H HD22 . LEU A 1 79  ? -0.75985  3.78074   31.68035  1.000 20.15652  ? 71  LEU A HD22 1 
ATOM   1174 H HD23 . LEU A 1 79  ? -1.78405  3.00427   32.61394  1.000 20.15652  ? 71  LEU A HD23 1 
ATOM   1175 N N    . LYS A 1 80  ? -0.57746  6.05165   36.72172  1.000 16.86569  ? 72  LYS A N    1 
ATOM   1176 C CA   A LYS A 1 80  ? 0.41484   6.58244   37.64726  0.304 25.81208  ? 72  LYS A CA   1 
ATOM   1177 C CA   B LYS A 1 80  ? 0.41422   6.58260   37.64822  0.696 25.91172  ? 72  LYS A CA   1 
ATOM   1178 C C    . LYS A 1 80  ? 0.71468   5.59713   38.76796  1.000 22.35862  ? 72  LYS A C    1 
ATOM   1179 O O    . LYS A 1 80  ? 1.84750   5.54021   39.25480  1.000 23.15620  ? 72  LYS A O    1 
ATOM   1180 C CB   A LYS A 1 80  ? -0.06989  7.91929   38.21014  0.304 30.69663  ? 72  LYS A CB   1 
ATOM   1181 C CB   B LYS A 1 80  ? -0.07246  7.91580   38.21779  0.696 30.75943  ? 72  LYS A CB   1 
ATOM   1182 C CG   A LYS A 1 80  ? 0.37877   9.16094   37.42620  0.304 38.77929  ? 72  LYS A CG   1 
ATOM   1183 C CG   B LYS A 1 80  ? 0.33814   9.16908   37.42672  0.696 39.02814  ? 72  LYS A CG   1 
ATOM   1184 C CD   A LYS A 1 80  ? 0.33899   8.95848   35.91778  0.304 35.19658  ? 72  LYS A CD   1 
ATOM   1185 C CD   B LYS A 1 80  ? 0.45555   8.93453   35.92898  0.696 35.41751  ? 72  LYS A CD   1 
ATOM   1186 C CE   A LYS A 1 80  ? 1.74777   8.95265   35.32329  0.304 32.69498  ? 72  LYS A CE   1 
ATOM   1187 C CE   B LYS A 1 80  ? 1.91235   8.75673   35.51084  0.696 33.95963  ? 72  LYS A CE   1 
ATOM   1188 N NZ   A LYS A 1 80  ? 1.77930   8.38373   33.93504  0.304 17.10236  ? 72  LYS A NZ   1 
ATOM   1189 N NZ   B LYS A 1 80  ? 2.60247   10.04914  35.21858  0.696 36.55522  ? 72  LYS A NZ   1 
ATOM   1190 H H    . LYS A 1 80  ? -1.33975  6.44890   36.74843  1.000 20.25585  ? 72  LYS A H    1 
ATOM   1191 H HA   . LYS A 1 80  ? 1.24430   6.74430   37.17113  1.000 31.11109  ? 72  LYS A HA   1 
ATOM   1192 H HB2  A LYS A 1 80  ? -1.03986  7.91518   38.21614  0.304 36.85297  ? 72  LYS A HB2  1 
ATOM   1193 H HB2  B LYS A 1 80  ? -1.04188  7.89851   38.24661  0.696 36.92834  ? 72  LYS A HB2  1 
ATOM   1194 H HB3  A LYS A 1 80  ? 0.26709   8.01054   39.11514  0.304 36.85297  ? 72  LYS A HB3  1 
ATOM   1195 H HB3  B LYS A 1 80  ? 0.28444   8.01186   39.11461  0.696 36.92834  ? 72  LYS A HB3  1 
ATOM   1196 H HG2  A LYS A 1 80  ? -0.20938  9.90100   37.64365  0.304 46.55217  ? 72  LYS A HG2  1 
ATOM   1197 H HG2  B LYS A 1 80  ? -0.32852  9.85969   37.56641  0.696 46.85079  ? 72  LYS A HG2  1 
ATOM   1198 H HG3  A LYS A 1 80  ? 1.29100   9.37819   37.67427  0.304 46.55217  ? 72  LYS A HG3  1 
ATOM   1199 H HG3  B LYS A 1 80  ? 1.20206   9.47227   37.74706  0.696 46.85079  ? 72  LYS A HG3  1 
ATOM   1200 H HD2  A LYS A 1 80  ? -0.08124  8.10745   35.71765  0.304 42.25292  ? 72  LYS A HD2  1 
ATOM   1201 H HD2  B LYS A 1 80  ? -0.03201  8.13096   35.68923  0.696 42.51803  ? 72  LYS A HD2  1 
ATOM   1202 H HD3  A LYS A 1 80  ? -0.16293  9.68068   35.50864  0.304 42.25292  ? 72  LYS A HD3  1 
ATOM   1203 H HD3  B LYS A 1 80  ? 0.09157   9.69768   35.45357  0.696 42.51803  ? 72  LYS A HD3  1 
ATOM   1204 H HE2  A LYS A 1 80  ? 2.07969   9.86322   35.28345  0.304 39.25100  ? 72  LYS A HE2  1 
ATOM   1205 H HE2  B LYS A 1 80  ? 2.39439   8.31735   36.22881  0.696 40.76858  ? 72  LYS A HE2  1 
ATOM   1206 H HE3  A LYS A 1 80  ? 2.32692   8.41264   35.88353  0.304 39.25100  ? 72  LYS A HE3  1 
ATOM   1207 H HE3  B LYS A 1 80  ? 1.94519   8.21332   34.70802  0.696 40.76858  ? 72  LYS A HE3  1 
ATOM   1208 H HZ1  A LYS A 1 80  ? 1.70965   7.49706   33.96779  0.304 20.53986  ? 72  LYS A HZ1  1 
ATOM   1209 H HZ1  B LYS A 1 80  ? 2.00717   10.70942  35.17669  0.696 43.88328  ? 72  LYS A HZ1  1 
ATOM   1210 H HZ2  A LYS A 1 80  ? 2.54483   8.59875   33.53527  0.304 20.53986  ? 72  LYS A HZ2  1 
ATOM   1211 H HZ2  B LYS A 1 80  ? 3.03055   9.99638   34.44009  0.696 43.88328  ? 72  LYS A HZ2  1 
ATOM   1212 H HZ3  A LYS A 1 80  ? 1.10260   8.70916   33.45727  0.304 20.53986  ? 72  LYS A HZ3  1 
ATOM   1213 H HZ3  B LYS A 1 80  ? 3.19151   10.23160  35.86033  0.696 43.88328  ? 72  LYS A HZ3  1 
ATOM   1214 N N    . ARG A 1 81  ? -0.27178  4.80088   39.18127  1.000 23.34266  ? 73  ARG A N    1 
ATOM   1215 C CA   . ARG A 1 81  ? 0.00062   3.83354   40.23513  1.000 23.74266  ? 73  ARG A CA   1 
ATOM   1216 C C    . ARG A 1 81  ? 0.68449   2.59248   39.68113  1.000 20.26603  ? 73  ARG A C    1 
ATOM   1217 O O    . ARG A 1 81  ? 1.53688   1.99984   40.35326  1.000 24.65242  ? 73  ARG A O    1 
ATOM   1218 C CB   . ARG A 1 81  ? -1.29277  3.46290   40.96385  1.000 35.36209  ? 73  ARG A CB   1 
ATOM   1219 C CG   . ARG A 1 81  ? -1.07229  2.53479   42.15857  1.000 62.30734  ? 73  ARG A CG   1 
ATOM   1220 C CD   . ARG A 1 81  ? -0.38020  3.23960   43.32908  1.000 65.67972  ? 73  ARG A CD   1 
ATOM   1221 N NE   . ARG A 1 81  ? -1.25032  4.21434   43.98640  1.000 74.92414  ? 73  ARG A NE   1 
ATOM   1222 C CZ   . ARG A 1 81  ? -2.40751  3.91963   44.57572  1.000 76.13847  ? 73  ARG A CZ   1 
ATOM   1223 N NH1  . ARG A 1 81  ? -2.85185  2.67022   44.61010  1.000 61.30770  ? 73  ARG A NH1  1 
ATOM   1224 N NH2  . ARG A 1 81  ? -3.12425  4.87912   45.14182  1.000 71.19038  ? 73  ARG A NH2  1 
ATOM   1225 H H    . ARG A 1 81  ? -1.07637  4.80277   38.87759  1.000 28.02821  ? 73  ARG A H    1 
ATOM   1226 H HA   . ARG A 1 81  ? 0.59486   4.23734   40.88683  1.000 28.50821  ? 73  ARG A HA   1 
ATOM   1227 H HB2  . ARG A 1 81  ? -1.71160  4.27445   41.29074  1.000 42.45153  ? 73  ARG A HB2  1 
ATOM   1228 H HB3  . ARG A 1 81  ? -1.88446  3.01163   40.34163  1.000 42.45153  ? 73  ARG A HB3  1 
ATOM   1229 H HG2  . ARG A 1 81  ? -1.93112  2.20839   42.46966  1.000 74.78583  ? 73  ARG A HG2  1 
ATOM   1230 H HG3  . ARG A 1 81  ? -0.51433  1.79050   41.88358  1.000 74.78583  ? 73  ARG A HG3  1 
ATOM   1231 H HD2  . ARG A 1 81  ? -0.11758  2.57783   43.98785  1.000 78.83268  ? 73  ARG A HD2  1 
ATOM   1232 H HD3  . ARG A 1 81  ? 0.40243   3.70846   42.99959  1.000 78.83268  ? 73  ARG A HD3  1 
ATOM   1233 H HE   . ARG A 1 81  ? -0.99661  5.03604   43.99274  1.000 89.92599  ? 73  ARG A HE   1 
ATOM   1234 H HH11 . ARG A 1 81  ? -2.39125  2.03994   44.24927  1.000 73.58627  ? 73  ARG A HH11 1 
ATOM   1235 H HH12 . ARG A 1 81  ? -3.60053  2.49048   44.99323  1.000 73.58627  ? 73  ARG A HH12 1 
ATOM   1236 H HH21 . ARG A 1 81  ? -2.84211  5.69141   45.12851  1.000 85.44547  ? 73  ARG A HH21 1 
ATOM   1237 H HH22 . ARG A 1 81  ? -3.87172  4.68974   45.52265  1.000 85.44547  ? 73  ARG A HH22 1 
ATOM   1238 N N    . LYS A 1 82  ? 0.32945   2.17338   38.46537  1.000 19.57729  ? 74  LYS A N    1 
ATOM   1239 C CA   . LYS A 1 82  ? 0.92307   0.95553   37.93052  1.000 14.51728  ? 74  LYS A CA   1 
ATOM   1240 C C    . LYS A 1 82  ? 2.24808   1.19385   37.22099  1.000 17.31350  ? 74  LYS A C    1 
ATOM   1241 O O    . LYS A 1 82  ? 3.14756   0.34790   37.30127  1.000 18.41507  ? 74  LYS A O    1 
ATOM   1242 C CB   . LYS A 1 82  ? -0.05077  0.26533   36.97058  1.000 24.83846  ? 74  LYS A CB   1 
ATOM   1243 C CG   . LYS A 1 82  ? 0.43106   -1.08773  36.49120  1.000 34.29311  ? 74  LYS A CG   1 
ATOM   1244 C CD   . LYS A 1 82  ? -0.70799  -1.91780  35.92535  1.000 48.61589  ? 74  LYS A CD   1 
ATOM   1245 C CE   . LYS A 1 82  ? -1.63210  -2.42137  37.02006  1.000 46.90395  ? 74  LYS A CE   1 
ATOM   1246 N NZ   . LYS A 1 82  ? -2.53551  -3.49814  36.52227  1.000 51.11806  ? 74  LYS A NZ   1 
ATOM   1247 H H    . LYS A 1 82  ? -0.23542  2.56664   37.94974  1.000 23.50977  ? 74  LYS A H    1 
ATOM   1248 H HA   . LYS A 1 82  ? 1.09285   0.35860   38.67600  1.000 17.43776  ? 74  LYS A HA   1 
ATOM   1249 H HB2  . LYS A 1 82  ? -0.89810  0.13541   37.42450  1.000 29.82317  ? 74  LYS A HB2  1 
ATOM   1250 H HB3  . LYS A 1 82  ? -0.17486  0.82978   36.19154  1.000 29.82317  ? 74  LYS A HB3  1 
ATOM   1251 H HG2  . LYS A 1 82  ? 1.09348   -0.96391  35.79351  1.000 41.16875  ? 74  LYS A HG2  1 
ATOM   1252 H HG3  . LYS A 1 82  ? 0.82024   -1.57226  37.23596  1.000 41.16875  ? 74  LYS A HG3  1 
ATOM   1253 H HD2  . LYS A 1 82  ? -1.22870  -1.37346  35.31424  1.000 58.35609  ? 74  LYS A HD2  1 
ATOM   1254 H HD3  . LYS A 1 82  ? -0.34375  -2.68560  35.45768  1.000 58.35609  ? 74  LYS A HD3  1 
ATOM   1255 H HE2  . LYS A 1 82  ? -1.10123  -2.78116  37.74781  1.000 56.30176  ? 74  LYS A HE2  1 
ATOM   1256 H HE3  . LYS A 1 82  ? -2.17994  -1.68770  37.34021  1.000 56.30176  ? 74  LYS A HE3  1 
ATOM   1257 H HZ1  . LYS A 1 82  ? -3.06878  -3.77566  37.17855  1.000 61.35870  ? 74  LYS A HZ1  1 
ATOM   1258 H HZ2  . LYS A 1 82  ? -3.03617  -3.19058  35.85381  1.000 61.35870  ? 74  LYS A HZ2  1 
ATOM   1259 H HZ3  . LYS A 1 82  ? -2.05485  -4.18764  36.22958  1.000 61.35870  ? 74  LYS A HZ3  1 
ATOM   1260 N N    . PHE A 1 83  ? 2.37277   2.32029   36.52080  1.000 13.90747  ? 75  PHE A N    1 
ATOM   1261 C CA   . PHE A 1 83  ? 3.54924   2.66252   35.72557  1.000 12.51505  ? 75  PHE A CA   1 
ATOM   1262 C C    . PHE A 1 83  ? 3.99288   4.07974   36.07002  1.000 14.38837  ? 75  PHE A C    1 
ATOM   1263 O O    . PHE A 1 83  ? 3.90509   5.00607   35.24752  1.000 15.56063  ? 75  PHE A O    1 
ATOM   1264 C CB   . PHE A 1 83  ? 3.22458   2.53193   34.24027  1.000 11.45145  ? 75  PHE A CB   1 
ATOM   1265 C CG   . PHE A 1 83  ? 2.58194   1.22339   33.86953  1.000 13.49934  ? 75  PHE A CG   1 
ATOM   1266 C CD1  . PHE A 1 83  ? 3.25786   0.03350   34.05237  1.000 13.19979  ? 75  PHE A CD1  1 
ATOM   1267 C CD2  . PHE A 1 83  ? 1.32675   1.18555   33.30566  1.000 16.52108  ? 75  PHE A CD2  1 
ATOM   1268 C CE1  . PHE A 1 83  ? 2.70245   -1.18212  33.69015  1.000 17.28791  ? 75  PHE A CE1  1 
ATOM   1269 C CE2  . PHE A 1 83  ? 0.74292   -0.03225  32.95226  1.000 18.55133  ? 75  PHE A CE2  1 
ATOM   1270 C CZ   . PHE A 1 83  ? 1.43798   -1.22051  33.14225  1.000 14.74518  ? 75  PHE A CZ   1 
ATOM   1271 H H    . PHE A 1 83  ? 1.76321   2.92619   36.49034  1.000 16.70598  ? 75  PHE A H    1 
ATOM   1272 H HA   . PHE A 1 83  ? 4.28066   2.06435   35.94493  1.000 15.03509  ? 75  PHE A HA   1 
ATOM   1273 H HB2  . PHE A 1 83  ? 2.61276   3.24242   33.99171  1.000 13.75876  ? 75  PHE A HB2  1 
ATOM   1274 H HB3  . PHE A 1 83  ? 4.04794   2.61074   33.73354  1.000 13.75876  ? 75  PHE A HB3  1 
ATOM   1275 H HD1  . PHE A 1 83  ? 4.10824   0.04882   34.42856  1.000 15.85677  ? 75  PHE A HD1  1 
ATOM   1276 H HD2  . PHE A 1 83  ? 0.86348   1.97846   33.15881  1.000 19.84232  ? 75  PHE A HD2  1 
ATOM   1277 H HE1  . PHE A 1 83  ? 3.18066   -1.96975  33.81603  1.000 20.76251  ? 75  PHE A HE1  1 
ATOM   1278 H HE2  . PHE A 1 83  ? -0.11301  -0.04836  32.58891  1.000 22.27862  ? 75  PHE A HE2  1 
ATOM   1279 H HZ   . PHE A 1 83  ? 1.05422   -2.03295  32.90234  1.000 17.71124  ? 75  PHE A HZ   1 
ATOM   1280 N N    . PRO A 1 84  ? 4.51585   4.27790   37.27899  1.000 13.17612  ? 76  PRO A N    1 
ATOM   1281 C CA   . PRO A 1 84  ? 4.73225   5.65060   37.76348  1.000 16.02502  ? 76  PRO A CA   1 
ATOM   1282 C C    . PRO A 1 84  ? 5.77208   6.40730   36.97571  1.000 17.01702  ? 76  PRO A C    1 
ATOM   1283 O O    . PRO A 1 84  ? 5.77281   7.64790   36.96342  1.000 15.72756  ? 76  PRO A O    1 
ATOM   1284 C CB   . PRO A 1 84  ? 5.17866   5.44156   39.22010  1.000 20.76948  ? 76  PRO A CB   1 
ATOM   1285 C CG   . PRO A 1 84  ? 5.77202   4.05430   39.23132  1.000 16.88780  ? 76  PRO A CG   1 
ATOM   1286 C CD   . PRO A 1 84  ? 4.90411   3.26233   38.27518  1.000 16.83324  ? 76  PRO A CD   1 
ATOM   1287 H HA   . PRO A 1 84  ? 3.89514   6.14038   37.74732  1.000 19.24705  ? 76  PRO A HA   1 
ATOM   1288 H HB2  . PRO A 1 84  ? 5.84057   6.10717   39.46450  1.000 24.94040  ? 76  PRO A HB2  1 
ATOM   1289 H HB3  . PRO A 1 84  ? 4.41431   5.49995   39.81446  1.000 24.94040  ? 76  PRO A HB3  1 
ATOM   1290 H HG2  . PRO A 1 84  ? 6.69171   4.08346   38.92436  1.000 20.28238  ? 76  PRO A HG2  1 
ATOM   1291 H HG3  . PRO A 1 84  ? 5.73270   3.68299   40.12658  1.000 20.28238  ? 76  PRO A HG3  1 
ATOM   1292 H HD2  . PRO A 1 84  ? 5.40777   2.54384   37.86165  1.000 20.21692  ? 76  PRO A HD2  1 
ATOM   1293 H HD3  . PRO A 1 84  ? 4.12508   2.90342   38.72815  1.000 20.21692  ? 76  PRO A HD3  1 
ATOM   1294 N N    . GLU A 1 85  ? 6.70710   5.70356   36.35435  1.000 15.37695  ? 77  GLU A N    1 
ATOM   1295 C CA   . GLU A 1 85  ? 7.77703   6.39901   35.66248  1.000 13.10565  ? 77  GLU A CA   1 
ATOM   1296 C C    . GLU A 1 85  ? 7.40102   6.60038   34.19707  1.000 22.98937  ? 77  GLU A C    1 
ATOM   1297 O O    . GLU A 1 85  ? 7.88788   5.91905   33.29485  1.000 18.83894  ? 77  GLU A O    1 
ATOM   1298 C CB   . GLU A 1 85  ? 9.09789   5.67877   35.76866  1.000 20.17071  ? 77  GLU A CB   1 
ATOM   1299 C CG   . GLU A 1 85  ? 9.99006   6.78752   35.36043  1.000 42.86140  ? 77  GLU A CG   1 
ATOM   1300 C CD   . GLU A 1 85  ? 11.18245  6.34546   35.21908  1.000 63.42035  ? 77  GLU A CD   1 
ATOM   1301 O OE1  . GLU A 1 85  ? 12.02797  7.21286   34.95556  1.000 70.20586  ? 77  GLU A OE1  1 
ATOM   1302 O OE2  . GLU A 1 85  ? 11.24969  5.14195   35.46650  1.000 62.90904  ? 77  GLU A OE2  1 
ATOM   1303 H H    . GLU A 1 85  ? 6.74139   4.84489   36.32094  1.000 18.46936  ? 77  GLU A H    1 
ATOM   1304 H HA   . GLU A 1 85  ? 7.86182   7.26397   36.09325  1.000 15.74380  ? 77  GLU A HA   1 
ATOM   1305 H HB2  . GLU A 1 85  ? 9.28487   5.38471   36.67391  1.000 24.22187  ? 77  GLU A HB2  1 
ATOM   1306 H HB3  . GLU A 1 85  ? 9.15796   4.92833   35.15700  1.000 24.22187  ? 77  GLU A HB3  1 
ATOM   1307 H HG2  . GLU A 1 85  ? 9.68999   7.15654   34.51504  1.000 51.45070  ? 77  GLU A HG2  1 
ATOM   1308 H HG3  . GLU A 1 85  ? 9.99001   7.47744   36.04227  1.000 51.45070  ? 77  GLU A HG3  1 
ATOM   1309 N N    . SER A 1 86  ? 6.56056   7.59404   33.96308  1.000 12.26207  ? 78  SER A N    1 
ATOM   1310 C CA   . SER A 1 86  ? 5.94830   7.77688   32.65661  1.000 11.05221  ? 78  SER A CA   1 
ATOM   1311 C C    . SER A 1 86  ? 5.43319   9.19808   32.59298  1.000 14.74516  ? 78  SER A C    1 
ATOM   1312 O O    . SER A 1 86  ? 5.35088   9.88821   33.60982  1.000 15.35649  ? 78  SER A O    1 
ATOM   1313 C CB   . SER A 1 86  ? 4.80759   6.78573   32.41392  1.000 14.84982  ? 78  SER A CB   1 
ATOM   1314 O OG   . SER A 1 86  ? 3.76410   6.97443   33.35461  1.000 15.89259  ? 78  SER A OG   1 
ATOM   1315 H H    . SER A 1 86  ? 6.32635   8.18018   34.54718  1.000 14.73151  ? 78  SER A H    1 
ATOM   1316 H HA   . SER A 1 86  ? 6.61665   7.63876   31.96731  1.000 13.27968  ? 78  SER A HA   1 
ATOM   1317 H HB2  . SER A 1 86  ? 4.45546   6.92269   31.52053  1.000 17.83681  ? 78  SER A HB2  1 
ATOM   1318 H HB3  . SER A 1 86  ? 5.15072   5.88258   32.50043  1.000 17.83681  ? 78  SER A HB3  1 
ATOM   1319 H HG   . SER A 1 86  ? 4.04176   6.80608   34.12931  1.000 19.08813  ? 78  SER A HG   1 
ATOM   1320 N N    . ILE A 1 87  ? 5.06529   9.60652   31.38012  1.000 10.54510  ? 79  ILE A N    1 
ATOM   1321 C CA   . ILE A 1 87  ? 4.48460   10.91042  31.07401  1.000 9.60260   ? 79  ILE A CA   1 
ATOM   1322 C C    . ILE A 1 87  ? 3.13128   10.66926  30.42365  1.000 9.27106   ? 79  ILE A C    1 
ATOM   1323 O O    . ILE A 1 87  ? 3.06003   10.03962  29.36213  1.000 13.85304  ? 79  ILE A O    1 
ATOM   1324 C CB   . ILE A 1 87  ? 5.39104   11.70969  30.13075  1.000 11.69296  ? 79  ILE A CB   1 
ATOM   1325 C CG1  . ILE A 1 87  ? 6.74907   11.94880  30.78232  1.000 14.94329  ? 79  ILE A CG1  1 
ATOM   1326 C CG2  . ILE A 1 87  ? 4.73630   13.03198  29.75152  1.000 12.91460  ? 79  ILE A CG2  1 
ATOM   1327 C CD1  . ILE A 1 87  ? 7.80029   12.41982  29.80131  1.000 16.36040  ? 79  ILE A CD1  1 
ATOM   1328 H H    . ILE A 1 87  ? 5.14755   9.11636   30.67828  1.000 12.67114  ? 79  ILE A H    1 
ATOM   1329 H HA   . ILE A 1 87  ? 4.35371   11.41298  31.89328  1.000 11.54015  ? 79  ILE A HA   1 
ATOM   1330 H HB   . ILE A 1 87  ? 5.52367   11.19249  29.32092  1.000 14.04857  ? 79  ILE A HB   1 
ATOM   1331 H HG12 . ILE A 1 87  ? 6.65398   12.62804  31.46824  1.000 17.94897  ? 79  ILE A HG12 1 
ATOM   1332 H HG13 . ILE A 1 87  ? 7.05904   11.11908  31.17777  1.000 17.94897  ? 79  ILE A HG13 1 
ATOM   1333 H HG21 . ILE A 1 87  ? 5.35689   13.54911  29.21455  1.000 15.51454  ? 79  ILE A HG21 1 
ATOM   1334 H HG22 . ILE A 1 87  ? 3.93028   12.85093  29.24315  1.000 15.51454  ? 79  ILE A HG22 1 
ATOM   1335 H HG23 . ILE A 1 87  ? 4.51457   13.51821  30.56104  1.000 15.51454  ? 79  ILE A HG23 1 
ATOM   1336 H HD11 . ILE A 1 87  ? 8.64467   12.52135  30.26780  1.000 19.64950  ? 79  ILE A HD11 1 
ATOM   1337 H HD12 . ILE A 1 87  ? 7.88998   11.76172  29.09438  1.000 19.64950  ? 79  ILE A HD12 1 
ATOM   1338 H HD13 . ILE A 1 87  ? 7.52443   13.27132  29.42748  1.000 19.64950  ? 79  ILE A HD13 1 
ATOM   1339 N N    . HIS A 1 88  ? 2.05642   11.16248  31.04507  1.000 9.94629   ? 80  HIS A N    1 
ATOM   1340 C CA   . HIS A 1 88  ? 0.70018   10.92022  30.54549  1.000 11.18594  ? 80  HIS A CA   1 
ATOM   1341 C C    . HIS A 1 88  ? 0.17875   12.19826  29.91238  1.000 9.87352   ? 80  HIS A C    1 
ATOM   1342 O O    . HIS A 1 88  ? -0.16387  13.15003  30.61753  1.000 13.05275  ? 80  HIS A O    1 
ATOM   1343 C CB   . HIS A 1 88  ? -0.24249  10.46502  31.65491  1.000 10.28206  ? 80  HIS A CB   1 
ATOM   1344 C CG   . HIS A 1 88  ? -1.60703  10.06447  31.17570  1.000 13.39556  ? 80  HIS A CG   1 
ATOM   1345 N ND1  . HIS A 1 88  ? -2.69225  9.96558   32.01995  1.000 13.46465  ? 80  HIS A ND1  1 
ATOM   1346 C CD2  . HIS A 1 88  ? -2.06422  9.74824   29.93922  1.000 11.44246  ? 80  HIS A CD2  1 
ATOM   1347 C CE1  . HIS A 1 88  ? -3.75216  9.57908   31.33083  1.000 12.07918  ? 80  HIS A CE1  1 
ATOM   1348 N NE2  . HIS A 1 88  ? -3.39960  9.44211   30.06738  1.000 11.02246  ? 80  HIS A NE2  1 
ATOM   1349 H H    . HIS A 1 88  ? 2.08844   11.64106  31.75889  1.000 11.95257  ? 80  HIS A H    1 
ATOM   1350 H HA   . HIS A 1 88  ? 0.74692   10.22304  29.87269  1.000 13.44015  ? 80  HIS A HA   1 
ATOM   1351 H HB2  . HIS A 1 88  ? 0.14998   9.69786   32.10026  1.000 12.35550  ? 80  HIS A HB2  1 
ATOM   1352 H HB3  . HIS A 1 88  ? -0.35413  11.19350  32.28559  1.000 12.35550  ? 80  HIS A HB3  1 
ATOM   1353 H HD2  . HIS A 1 88  ? -1.56853  9.73981   29.15238  1.000 13.74797  ? 80  HIS A HD2  1 
ATOM   1354 H HE1  . HIS A 1 88  ? -4.60184  9.42926   31.67794  1.000 14.51203  ? 80  HIS A HE1  1 
ATOM   1355 N N    . PHE A 1 89  ? 0.14434   12.21729  28.58609  1.000 10.44793  ? 81  PHE A N    1 
ATOM   1356 C CA   . PHE A 1 89  ? -0.45138  13.30130  27.81648  1.000 12.47607  ? 81  PHE A CA   1 
ATOM   1357 C C    . PHE A 1 89  ? -1.87475  12.86518  27.48384  1.000 12.21129  ? 81  PHE A C    1 
ATOM   1358 O O    . PHE A 1 89  ? -2.09478  12.07741  26.55821  1.000 10.63322  ? 81  PHE A O    1 
ATOM   1359 C CB   . PHE A 1 89  ? 0.36599   13.57809  26.56268  1.000 10.26519  ? 81  PHE A CB   1 
ATOM   1360 C CG   . PHE A 1 89  ? 1.65845   14.30369  26.81093  1.000 10.52528  ? 81  PHE A CG   1 
ATOM   1361 C CD1  . PHE A 1 89  ? 1.68536   15.50118  27.50411  1.000 14.28209  ? 81  PHE A CD1  1 
ATOM   1362 C CD2  . PHE A 1 89  ? 2.84337   13.81308  26.29768  1.000 11.02110  ? 81  PHE A CD2  1 
ATOM   1363 C CE1  . PHE A 1 89  ? 2.89184   16.18794  27.69832  1.000 14.06987  ? 81  PHE A CE1  1 
ATOM   1364 C CE2  . PHE A 1 89  ? 4.04551   14.49838  26.47798  1.000 13.13557  ? 81  PHE A CE2  1 
ATOM   1365 C CZ   . PHE A 1 89  ? 4.06483   15.68173  27.18009  1.000 14.02975  ? 81  PHE A CZ   1 
ATOM   1366 H H    . PHE A 1 89  ? 0.47059   11.59254  28.09329  1.000 12.55454  ? 81  PHE A H    1 
ATOM   1367 H HA   . PHE A 1 89  ? -0.48063  14.11783  28.33928  1.000 14.98831  ? 81  PHE A HA   1 
ATOM   1368 H HB2  . PHE A 1 89  ? 0.58133   12.73163  26.14074  1.000 12.33525  ? 81  PHE A HB2  1 
ATOM   1369 H HB3  . PHE A 1 89  ? -0.16527  14.12295  25.96118  1.000 12.33525  ? 81  PHE A HB3  1 
ATOM   1370 H HD1  . PHE A 1 89  ? 0.89501   15.85384  27.84453  1.000 17.15553  ? 81  PHE A HD1  1 
ATOM   1371 H HD2  . PHE A 1 89  ? 2.83990   13.01272  25.82408  1.000 13.24234  ? 81  PHE A HD2  1 
ATOM   1372 H HE1  . PHE A 1 89  ? 2.90102   16.98530  28.17691  1.000 16.90087  ? 81  PHE A HE1  1 
ATOM   1373 H HE2  . PHE A 1 89  ? 4.83387   14.15526  26.12352  1.000 15.77970  ? 81  PHE A HE2  1 
ATOM   1374 H HZ   . PHE A 1 89  ? 4.86562   16.13798  27.30446  1.000 16.85273  ? 81  PHE A HZ   1 
ATOM   1375 N N    . CYS A 1 90  ? -2.84120  13.40633  28.22736  1.000 12.30571  ? 82  CYS A N    1 
ATOM   1376 C CA   . CYS A 1 90  ? -4.25067  13.04277  28.11987  1.000 12.20210  ? 82  CYS A CA   1 
ATOM   1377 C C    . CYS A 1 90  ? -5.05955  14.25225  27.67164  1.000 12.13191  ? 82  CYS A C    1 
ATOM   1378 O O    . CYS A 1 90  ? -5.10555  15.26303  28.37780  1.000 13.28490  ? 82  CYS A O    1 
ATOM   1379 C CB   . CYS A 1 90  ? -4.76681  12.54635  29.46346  1.000 13.37275  ? 82  CYS A CB   1 
ATOM   1380 S SG   . CYS A 1 90  ? -6.50135  12.10895  29.49281  1.000 14.19501  ? 82  CYS A SG   1 
ATOM   1381 H H    . CYS A 1 90  ? -2.69689  14.00933  28.82331  1.000 14.78388  ? 82  CYS A H    1 
ATOM   1382 H HA   . CYS A 1 90  ? -4.35194  12.34843  27.45014  1.000 14.65954  ? 82  CYS A HA   1 
ATOM   1383 H HB2  . CYS A 1 90  ? -4.26319  11.75560  29.71243  1.000 16.06432  ? 82  CYS A HB2  1 
ATOM   1384 H HB3  . CYS A 1 90  ? -4.63217  13.24623  30.12144  1.000 16.06432  ? 82  CYS A HB3  1 
ATOM   1385 H HG   . CYS A 1 90  ? -6.79837  11.76332  30.60291  1.000 17.05103  ? 82  CYS A HG   1 
ATOM   1386 N N    . ARG A 1 91  ? -5.71349  14.13446  26.51430  1.000 12.85551  ? 83  ARG A N    1 
ATOM   1387 C CA   . ARG A 1 91  ? -6.41576  15.28041  25.93747  1.000 11.51364  ? 83  ARG A CA   1 
ATOM   1388 C C    . ARG A 1 91  ? -7.52986  15.77635  26.85212  1.000 12.91644  ? 83  ARG A C    1 
ATOM   1389 O O    . ARG A 1 91  ? -7.76220  16.98753  26.96525  1.000 14.26568  ? 83  ARG A O    1 
ATOM   1390 C CB   . ARG A 1 91  ? -6.98487  14.90352  24.57221  1.000 17.17416  ? 83  ARG A CB   1 
ATOM   1391 C CG   . ARG A 1 91  ? -5.95184  14.67456  23.48229  1.000 10.85570  ? 83  ARG A CG   1 
ATOM   1392 C CD   . ARG A 1 91  ? -6.62480  14.61627  22.10550  1.000 12.95269  ? 83  ARG A CD   1 
ATOM   1393 N NE   . ARG A 1 91  ? -7.09139  15.93193  21.70011  1.000 15.28919  ? 83  ARG A NE   1 
ATOM   1394 C CZ   . ARG A 1 91  ? -8.34736  16.24359  21.42380  1.000 15.78178  ? 83  ARG A CZ   1 
ATOM   1395 N NH1  . ARG A 1 91  ? -9.29745  15.31991  21.48851  1.000 24.56124  ? 83  ARG A NH1  1 
ATOM   1396 N NH2  . ARG A 1 91  ? -8.64398  17.49394  21.08743  1.000 17.65777  ? 83  ARG A NH2  1 
ATOM   1397 H H    . ARG A 1 91  ? -5.76535  13.41268  26.04960  1.000 15.44364  ? 83  ARG A H    1 
ATOM   1398 H HA   . ARG A 1 91  ? -5.78094  16.00445  25.82063  1.000 13.83338  ? 83  ARG A HA   1 
ATOM   1399 H HB2  . ARG A 1 91  ? -7.49232  14.08241  24.66800  1.000 20.62601  ? 83  ARG A HB2  1 
ATOM   1400 H HB3  . ARG A 1 91  ? -7.56669  15.62027  24.27446  1.000 20.62601  ? 83  ARG A HB3  1 
ATOM   1401 H HG2  . ARG A 1 91  ? -5.31221  15.40379  23.48265  1.000 13.04387  ? 83  ARG A HG2  1 
ATOM   1402 H HG3  . ARG A 1 91  ? -5.49560  13.83299  23.63880  1.000 13.04387  ? 83  ARG A HG3  1 
ATOM   1403 H HD2  . ARG A 1 91  ? -5.98686  14.29976  21.44690  1.000 15.56025  ? 83  ARG A HD2  1 
ATOM   1404 H HD3  . ARG A 1 91  ? -7.38718  14.01773  22.14330  1.000 15.56025  ? 83  ARG A HD3  1 
ATOM   1405 H HE   . ARG A 1 91  ? -6.50467  16.55729  21.63466  1.000 18.36405  ? 83  ARG A HE   1 
ATOM   1406 H HH11 . ARG A 1 91  ? -9.09858  14.51335  21.71102  1.000 29.49051  ? 83  ARG A HH11 1 
ATOM   1407 H HH12 . ARG A 1 91  ? -10.11220 15.52770  21.30794  1.000 29.49051  ? 83  ARG A HH12 1 
ATOM   1408 H HH21 . ARG A 1 91  ? -8.02346  18.08830  21.05152  1.000 21.20635  ? 83  ARG A HH21 1 
ATOM   1409 H HH22 . ARG A 1 91  ? -9.45653  17.70907  20.90556  1.000 21.20635  ? 83  ARG A HH22 1 
ATOM   1410 N N    . GLU A 1 92  ? -8.23580  14.86096  27.50898  1.000 13.68598  ? 84  GLU A N    1 
ATOM   1411 C CA   . GLU A 1 92  ? -9.30288  15.29277  28.40438  1.000 14.87459  ? 84  GLU A CA   1 
ATOM   1412 C C    . GLU A 1 92  ? -8.77862  16.11717  29.57686  1.000 17.35891  ? 84  GLU A C    1 
ATOM   1413 O O    . GLU A 1 92  ? -9.52535  16.92322  30.13817  1.000 19.58482  ? 84  GLU A O    1 
ATOM   1414 C CB   . GLU A 1 92  ? -10.08160 14.09294  28.93372  1.000 16.91060  ? 84  GLU A CB   1 
ATOM   1415 C CG   . GLU A 1 92  ? -11.21451 14.49042  29.85501  1.000 24.13702  ? 84  GLU A CG   1 
ATOM   1416 C CD   . GLU A 1 92  ? -12.15759 13.34518  30.16582  1.000 24.86029  ? 84  GLU A CD   1 
ATOM   1417 O OE1  . GLU A 1 92  ? -11.86275 12.18586  29.80199  1.000 21.61443  ? 84  GLU A OE1  1 
ATOM   1418 O OE2  . GLU A 1 92  ? -13.20240 13.61156  30.79209  1.000 31.27414  ? 84  GLU A OE2  1 
ATOM   1419 H H    . GLU A 1 92  ? -8.12082  14.01035  27.45567  1.000 16.44020  ? 84  GLU A H    1 
ATOM   1420 H HA   . GLU A 1 92  ? -9.91635  15.84435  27.89417  1.000 17.86653  ? 84  GLU A HA   1 
ATOM   1421 H HB2  . GLU A 1 92  ? -10.46016 13.60686  28.18450  1.000 20.30974  ? 84  GLU A HB2  1 
ATOM   1422 H HB3  . GLU A 1 92  ? -9.47774  13.51896  29.43051  1.000 20.30974  ? 84  GLU A HB3  1 
ATOM   1423 H HG2  . GLU A 1 92  ? -10.84250 14.80667  30.69316  1.000 28.98145  ? 84  GLU A HG2  1 
ATOM   1424 H HG3  . GLU A 1 92  ? -11.73013 15.19581  29.43376  1.000 28.98145  ? 84  GLU A HG3  1 
ATOM   1425 N N    . LEU A 1 93  ? -7.51139  15.95945  29.93925  1.000 11.82675  ? 85  LEU A N    1 
ATOM   1426 C CA   . LEU A 1 93  ? -6.89573  16.69556  31.03468  1.000 13.44482  ? 85  LEU A CA   1 
ATOM   1427 C C    . LEU A 1 93  ? -6.07372  17.88720  30.56185  1.000 14.94037  ? 85  LEU A C    1 
ATOM   1428 O O    . LEU A 1 93  ? -5.58110  18.64721  31.39814  1.000 16.69500  ? 85  LEU A O    1 
ATOM   1429 C CB   . LEU A 1 93  ? -5.99840  15.75633  31.86331  1.000 11.71687  ? 85  LEU A CB   1 
ATOM   1430 C CG   . LEU A 1 93  ? -6.70717  14.56764  32.52219  1.000 14.07538  ? 85  LEU A CG   1 
ATOM   1431 C CD1  . LEU A 1 93  ? -5.74361  13.69322  33.27804  1.000 18.63873  ? 85  LEU A CD1  1 
ATOM   1432 C CD2  . LEU A 1 93  ? -7.80325  15.07325  33.45560  1.000 19.28605  ? 85  LEU A CD2  1 
ATOM   1433 H H    . LEU A 1 93  ? -6.97048  15.41381  29.55288  1.000 14.20912  ? 85  LEU A H    1 
ATOM   1434 H HA   . LEU A 1 93  ? -7.59977  17.02951  31.61236  1.000 16.15080  ? 85  LEU A HA   1 
ATOM   1435 H HB2  . LEU A 1 93  ? -5.31442  15.39557  31.27772  1.000 14.07726  ? 85  LEU A HB2  1 
ATOM   1436 H HB3  . LEU A 1 93  ? -5.58798  16.27610  32.57203  1.000 14.07726  ? 85  LEU A HB3  1 
ATOM   1437 H HG   . LEU A 1 93  ? -7.10539  14.02147  31.82647  1.000 16.90748  ? 85  LEU A HG   1 
ATOM   1438 H HD11 . LEU A 1 93  ? -6.23081  12.95161  33.66989  1.000 22.38350  ? 85  LEU A HD11 1 
ATOM   1439 H HD12 . LEU A 1 93  ? -5.07127  13.35954  32.66363  1.000 22.38350  ? 85  LEU A HD12 1 
ATOM   1440 H HD13 . LEU A 1 93  ? -5.32210  14.21800  33.97650  1.000 22.38350  ? 85  LEU A HD13 1 
ATOM   1441 H HD21 . LEU A 1 93  ? -8.15020  14.32680  33.96877  1.000 23.16029  ? 85  LEU A HD21 1 
ATOM   1442 H HD22 . LEU A 1 93  ? -7.42734  15.73887  34.05272  1.000 23.16029  ? 85  LEU A HD22 1 
ATOM   1443 H HD23 . LEU A 1 93  ? -8.51275  15.46800  32.92487  1.000 23.16029  ? 85  LEU A HD23 1 
ATOM   1444 N N    . ASP A 1 94  ? -5.93657  18.09396  29.24978  1.000 13.32195  ? 86  ASP A N    1 
ATOM   1445 C CA   . ASP A 1 94  ? -5.06879  19.15865  28.74104  1.000 12.43853  ? 86  ASP A CA   1 
ATOM   1446 C C    . ASP A 1 94  ? -5.56049  19.53545  27.34635  1.000 14.98708  ? 86  ASP A C    1 
ATOM   1447 O O    . ASP A 1 94  ? -5.27012  18.82463  26.38313  1.000 14.48721  ? 86  ASP A O    1 
ATOM   1448 C CB   . ASP A 1 94  ? -3.62067  18.69806  28.71029  1.000 12.17544  ? 86  ASP A CB   1 
ATOM   1449 C CG   . ASP A 1 94  ? -2.67738  19.73739  28.14875  1.000 15.46620  ? 86  ASP A CG   1 
ATOM   1450 O OD1  . ASP A 1 94  ? -3.12595  20.82054  27.69246  1.000 15.07396  ? 86  ASP A OD1  1 
ATOM   1451 O OD2  . ASP A 1 94  ? -1.45768  19.47308  28.16536  1.000 16.53912  ? 86  ASP A OD2  1 
ATOM   1452 H H    . ASP A 1 94  ? -6.33175  17.63542  28.63889  1.000 16.00336  ? 86  ASP A H    1 
ATOM   1453 H HA   . ASP A 1 94  ? -5.14432  19.93886  29.31241  1.000 14.94325  ? 86  ASP A HA   1 
ATOM   1454 H HB2  . ASP A 1 94  ? -3.33602  18.49493  29.61506  1.000 14.62755  ? 86  ASP A HB2  1 
ATOM   1455 H HB3  . ASP A 1 94  ? -3.55466  17.90493  28.15578  1.000 14.62755  ? 86  ASP A HB3  1 
ATOM   1456 N N    . ASN A 1 95  ? -6.26507  20.66921  27.24820  1.000 13.44915  ? 87  ASN A N    1 
ATOM   1457 C CA   . ASN A 1 95  ? -6.82251  21.11773  25.97783  1.000 11.01380  ? 87  ASN A CA   1 
ATOM   1458 C C    . ASN A 1 95  ? -5.75819  21.56522  24.98687  1.000 11.79139  ? 87  ASN A C    1 
ATOM   1459 O O    . ASN A 1 95  ? -6.08958  21.84132  23.82714  1.000 14.85261  ? 87  ASN A O    1 
ATOM   1460 C CB   . ASN A 1 95  ? -7.81394  22.25901  26.23255  1.000 12.12524  ? 87  ASN A CB   1 
ATOM   1461 C CG   . ASN A 1 95  ? -9.08684  21.78496  26.92560  1.000 22.39571  ? 87  ASN A CG   1 
ATOM   1462 O OD1  . ASN A 1 95  ? -9.51291  20.64757  26.76039  1.000 27.56905  ? 87  ASN A OD1  1 
ATOM   1463 N ND2  . ASN A 1 95  ? -9.69572  22.65838  27.69810  1.000 18.96756  ? 87  ASN A ND2  1 
ATOM   1464 H H    . ASN A 1 95  ? -6.43237  21.19516  27.90773  1.000 16.15600  ? 87  ASN A H    1 
ATOM   1465 H HA   . ASN A 1 95  ? -7.30420  20.38213  25.56824  1.000 13.23359  ? 87  ASN A HA   1 
ATOM   1466 H HB2  . ASN A 1 95  ? -7.39272  22.92396  26.79939  1.000 14.56731  ? 87  ASN A HB2  1 
ATOM   1467 H HB3  . ASN A 1 95  ? -8.06391  22.65682  25.38392  1.000 14.56731  ? 87  ASN A HB3  1 
ATOM   1468 H HD21 . ASN A 1 95  ? -10.41750 22.43806  28.11052  1.000 22.77810  ? 87  ASN A HD21 1 
ATOM   1469 H HD22 . ASN A 1 95  ? -9.37200  23.44973  27.79072  1.000 22.77810  ? 87  ASN A HD22 1 
ATOM   1470 N N    . ASN A 1 96  ? -4.49990  21.64700  25.40634  1.000 10.98690  ? 88  ASN A N    1 
ATOM   1471 C CA   . ASN A 1 96  ? -3.44009  22.02407  24.48558  1.000 12.10263  ? 88  ASN A CA   1 
ATOM   1472 C C    . ASN A 1 96  ? -3.04950  20.89301  23.54616  1.000 12.70553  ? 88  ASN A C    1 
ATOM   1473 O O    . ASN A 1 96  ? -2.40753  21.15433  22.52058  1.000 13.73767  ? 88  ASN A O    1 
ATOM   1474 C CB   . ASN A 1 96  ? -2.21022  22.48860  25.25789  1.000 13.92970  ? 88  ASN A CB   1 
ATOM   1475 C CG   . ASN A 1 96  ? -2.46526  23.75763  26.04773  1.000 18.36283  ? 88  ASN A CG   1 
ATOM   1476 O OD1  . ASN A 1 96  ? -2.75255  24.81435  25.48064  1.000 19.31007  ? 88  ASN A OD1  1 
ATOM   1477 N ND2  . ASN A 1 96  ? -2.37269  23.65733  27.36073  1.000 14.71872  ? 88  ASN A ND2  1 
ATOM   1478 H H    . ASN A 1 96  ? -4.23865  21.49049  26.21061  1.000 13.20130  ? 88  ASN A H    1 
ATOM   1479 H HA   . ASN A 1 96  ? -3.75247  22.76729  23.94620  1.000 14.54018  ? 88  ASN A HA   1 
ATOM   1480 H HB2  . ASN A 1 96  ? -1.94645  21.79397  25.88144  1.000 16.73266  ? 88  ASN A HB2  1 
ATOM   1481 H HB3  . ASN A 1 96  ? -1.49016  22.66337  24.63190  1.000 16.73266  ? 88  ASN A HB3  1 
ATOM   1482 H HD21 . ASN A 1 96  ? -2.50803  24.34773  27.85532  1.000 17.67949  ? 88  ASN A HD21 1 
ATOM   1483 H HD22 . ASN A 1 96  ? -2.17705  22.90158  27.72152  1.000 17.67949  ? 88  ASN A HD22 1 
ATOM   1484 N N    . ILE A 1 97  ? -3.43696  19.66123  23.85410  1.000 13.64003  ? 89  ILE A N    1 
ATOM   1485 C CA   . ILE A 1 97  ? -3.05937  18.50783  23.03989  1.000 12.97360  ? 89  ILE A CA   1 
ATOM   1486 C C    . ILE A 1 97  ? -4.00387  18.35047  21.85449  1.000 13.10497  ? 89  ILE A C    1 
ATOM   1487 O O    . ILE A 1 97  ? -5.21281  18.14250  22.04765  1.000 13.71091  ? 89  ILE A O    1 
ATOM   1488 C CB   . ILE A 1 97  ? -3.05551  17.22560  23.88007  1.000 11.08097  ? 89  ILE A CB   1 
ATOM   1489 C CG1  . ILE A 1 97  ? -2.12153  17.37231  25.07997  1.000 11.95747  ? 89  ILE A CG1  1 
ATOM   1490 C CG2  . ILE A 1 97  ? -2.63970  16.00618  23.04992  1.000 12.75524  ? 89  ILE A CG2  1 
ATOM   1491 C CD1  . ILE A 1 97  ? -2.26432  16.26494  26.08625  1.000 11.95125  ? 89  ILE A CD1  1 
ATOM   1492 H H    . ILE A 1 97  ? -3.92335  19.46361  24.53526  1.000 16.38506  ? 89  ILE A H    1 
ATOM   1493 H HA   . ILE A 1 97  ? -2.17134  18.67635  22.68788  1.000 15.58534  ? 89  ILE A HA   1 
ATOM   1494 H HB   . ILE A 1 97  ? -3.96322  17.08761  24.19301  1.000 13.31419  ? 89  ILE A HB   1 
ATOM   1495 H HG12 . ILE A 1 97  ? -1.20415  17.37160  24.76484  1.000 14.36599  ? 89  ILE A HG12 1 
ATOM   1496 H HG13 . ILE A 1 97  ? -2.31744  18.20952  25.52896  1.000 14.36599  ? 89  ILE A HG13 1 
ATOM   1497 H HG21 . ILE A 1 97  ? -2.60080  15.22862  23.62852  1.000 15.32331  ? 89  ILE A HG21 1 
ATOM   1498 H HG22 . ILE A 1 97  ? -3.29406  15.86387  22.34815  1.000 15.32331  ? 89  ILE A HG22 1 
ATOM   1499 H HG23 . ILE A 1 97  ? -1.76723  16.17227  22.65991  1.000 15.32331  ? 89  ILE A HG23 1 
ATOM   1500 H HD11 . ILE A 1 97  ? -1.67416  16.44115  26.83562  1.000 14.35852  ? 89  ILE A HD11 1 
ATOM   1501 H HD12 . ILE A 1 97  ? -3.18469  16.23166  26.39074  1.000 14.35852  ? 89  ILE A HD12 1 
ATOM   1502 H HD13 . ILE A 1 97  ? -2.02412  15.42402  25.66665  1.000 14.35852  ? 89  ILE A HD13 1 
ATOM   1503 N N    . PRO A 1 98  ? -3.49731  18.40873  20.62471  1.000 11.22132  ? 90  PRO A N    1 
ATOM   1504 C CA   . PRO A 1 98  ? -4.37331  18.25862  19.45468  1.000 15.90869  ? 90  PRO A CA   1 
ATOM   1505 C C    . PRO A 1 98  ? -4.95323  16.85518  19.34000  1.000 13.87358  ? 90  PRO A C    1 
ATOM   1506 O O    . PRO A 1 98  ? -4.46039  15.89390  19.93556  1.000 16.01328  ? 90  PRO A O    1 
ATOM   1507 C CB   . PRO A 1 98  ? -3.45239  18.56316  18.26572  1.000 18.67758  ? 90  PRO A CB   1 
ATOM   1508 C CG   . PRO A 1 98  ? -2.24813  19.22481  18.82192  1.000 17.40270  ? 90  PRO A CG   1 
ATOM   1509 C CD   . PRO A 1 98  ? -2.10753  18.72813  20.24574  1.000 16.62599  ? 90  PRO A CD   1 
ATOM   1510 H HA   . PRO A 1 98  ? -5.09362  18.90704  19.49478  1.000 19.10746  ? 90  PRO A HA   1 
ATOM   1511 H HB2  . PRO A 1 98  ? -3.21238  17.73480  17.82175  1.000 22.43012  ? 90  PRO A HB2  1 
ATOM   1512 H HB3  . PRO A 1 98  ? -3.90933  19.15198  17.64491  1.000 22.43012  ? 90  PRO A HB3  1 
ATOM   1513 H HG2  . PRO A 1 98  ? -1.47060  18.97977  18.29626  1.000 20.90027  ? 90  PRO A HG2  1 
ATOM   1514 H HG3  . PRO A 1 98  ? -2.36941  20.18707  18.80616  1.000 20.90027  ? 90  PRO A HG3  1 
ATOM   1515 H HD2  . PRO A 1 98  ? -1.54785  17.93675  20.28281  1.000 19.96821  ? 90  PRO A HD2  1 
ATOM   1516 H HD3  . PRO A 1 98  ? -1.74239  19.41988  20.81938  1.000 19.96821  ? 90  PRO A HD3  1 
ATOM   1517 N N    . ALA A 1 99  ? -5.99704  16.74310  18.51348  1.000 12.07757  ? 91  ALA A N    1 
ATOM   1518 C CA   . ALA A 1 99  ? -6.63505  15.45274  18.28014  1.000 14.67576  ? 91  ALA A CA   1 
ATOM   1519 C C    . ALA A 1 99  ? -5.61684  14.46739  17.72707  1.000 11.44924  ? 91  ALA A C    1 
ATOM   1520 O O    . ALA A 1 99  ? -4.82870  14.80077  16.83564  1.000 16.24872  ? 91  ALA A O    1 
ATOM   1521 C CB   . ALA A 1 99  ? -7.78949  15.58152  17.29696  1.000 14.85840  ? 91  ALA A CB   1 
ATOM   1522 H H    . ALA A 1 99  ? -6.35031  17.39645  18.07996  1.000 14.51010  ? 91  ALA A H    1 
ATOM   1523 H HA   . ALA A 1 99  ? -6.99086  15.12179  19.11965  1.000 17.62794  ? 91  ALA A HA   1 
ATOM   1524 H HB1  . ALA A 1 99  ? -8.18399  14.70653  17.15675  1.000 17.84710  ? 91  ALA A HB1  1 
ATOM   1525 H HB2  . ALA A 1 99  ? -8.45141  16.18772  17.66477  1.000 17.84710  ? 91  ALA A HB2  1 
ATOM   1526 H HB3  . ALA A 1 99  ? -7.45175  15.93049  16.45729  1.000 17.84710  ? 91  ALA A HB3  1 
ATOM   1527 N N    . LYS A 1 100 ? -5.63603  13.24408  18.26111  1.000 12.57460  ? 92  LYS A N    1 
ATOM   1528 C CA   . LYS A 1 100 ? -4.57381  12.29395  17.93836  1.000 11.66473  ? 92  LYS A CA   1 
ATOM   1529 C C    . LYS A 1 100 ? -4.57026  11.93532  16.45037  1.000 11.88338  ? 92  LYS A C    1 
ATOM   1530 O O    . LYS A 1 100 ? -3.50682  11.84308  15.82426  1.000 13.43394  ? 92  LYS A O    1 
ATOM   1531 C CB   . LYS A 1 100 ? -4.71818  11.02913  18.79476  1.000 14.37151  ? 92  LYS A CB   1 
ATOM   1532 C CG   . LYS A 1 100 ? -4.42403  11.23687  20.28624  1.000 14.90852  ? 92  LYS A CG   1 
ATOM   1533 C CD   . LYS A 1 100 ? -4.81338  10.00443  21.10431  1.000 18.52704  ? 92  LYS A CD   1 
ATOM   1534 C CE   . LYS A 1 100 ? -4.09033  8.76123   20.61061  1.000 17.89485  ? 92  LYS A CE   1 
ATOM   1535 N NZ   . LYS A 1 100 ? -4.34996  7.58441   21.49023  1.000 16.04703  ? 92  LYS A NZ   1 
ATOM   1536 H H    . LYS A 1 100 ? -6.23778  12.94775  18.79933  1.000 15.10654  ? 92  LYS A H    1 
ATOM   1537 H HA   . LYS A 1 100 ? -3.72187  12.70823  18.14687  1.000 14.01470  ? 92  LYS A HA   1 
ATOM   1538 H HB2  . LYS A 1 100 ? -5.62941  10.70569  18.71764  1.000 17.26284  ? 92  LYS A HB2  1 
ATOM   1539 H HB3  . LYS A 1 100 ? -4.09931  10.35938  18.46412  1.000 17.26284  ? 92  LYS A HB3  1 
ATOM   1540 H HG2  . LYS A 1 100 ? -3.47534  11.39801  20.40833  1.000 17.90724  ? 92  LYS A HG2  1 
ATOM   1541 H HG3  . LYS A 1 100 ? -4.93398  11.99460  20.61290  1.000 17.90724  ? 92  LYS A HG3  1 
ATOM   1542 H HD2  . LYS A 1 100 ? -4.57594  10.14698  22.03393  1.000 22.24947  ? 92  LYS A HD2  1 
ATOM   1543 H HD3  . LYS A 1 100 ? -5.76838  9.85407   21.02512  1.000 22.24947  ? 92  LYS A HD3  1 
ATOM   1544 H HE2  . LYS A 1 100 ? -4.39796  8.54593   19.71623  1.000 21.49084  ? 92  LYS A HE2  1 
ATOM   1545 H HE3  . LYS A 1 100 ? -3.13499  8.92895   20.60144  1.000 21.49084  ? 92  LYS A HE3  1 
ATOM   1546 H HZ1  . LYS A 1 100 ? -4.05567  6.84115   21.09903  1.000 19.27346  ? 92  LYS A HZ1  1 
ATOM   1547 H HZ2  . LYS A 1 100 ? -3.92985  7.68721   22.26807  1.000 19.27346  ? 92  LYS A HZ2  1 
ATOM   1548 H HZ3  . LYS A 1 100 ? -5.22329  7.50460   21.64199  1.000 19.27346  ? 92  LYS A HZ3  1 
ATOM   1549 N N    . GLN A 1 101 ? -5.74238  11.64464  15.88483  1.000 11.99511  ? 93  GLN A N    1 
ATOM   1550 C CA   . GLN A 1 101 ? -5.75972  11.06425  14.54658  1.000 14.14776  ? 93  GLN A CA   1 
ATOM   1551 C C    . GLN A 1 101 ? -5.30480  12.04416  13.47584  1.000 19.81485  ? 93  GLN A C    1 
ATOM   1552 O O    . GLN A 1 101 ? -4.99319  11.60382  12.36333  1.000 18.31432  ? 93  GLN A O    1 
ATOM   1553 C CB   . GLN A 1 101 ? -7.14975  10.52506  14.20839  1.000 15.10239  ? 93  GLN A CB   1 
ATOM   1554 C CG   . GLN A 1 101 ? -7.54397  9.35215   15.08825  1.000 16.27230  ? 93  GLN A CG   1 
ATOM   1555 C CD   . GLN A 1 101 ? -8.92833  8.83925   14.83733  1.000 23.18276  ? 93  GLN A CD   1 
ATOM   1556 O OE1  . GLN A 1 101 ? -9.75355  8.79042   15.75032  1.000 22.98195  ? 93  GLN A OE1  1 
ATOM   1557 N NE2  . GLN A 1 101 ? -9.19580  8.44184   13.60563  1.000 24.43491  ? 93  GLN A NE2  1 
ATOM   1558 H H    . GLN A 1 101 ? -6.51355  11.77023  16.24416  1.000 14.41116  ? 93  GLN A H    1 
ATOM   1559 H HA   . GLN A 1 101 ? -5.15083  10.30925  14.53522  1.000 16.99433  ? 93  GLN A HA   1 
ATOM   1560 H HB2  . GLN A 1 101 ? -7.80315  11.23071  14.33501  1.000 18.13989  ? 93  GLN A HB2  1 
ATOM   1561 H HB3  . GLN A 1 101 ? -7.15833  10.22667  13.28547  1.000 18.13989  ? 93  GLN A HB3  1 
ATOM   1562 H HG2  . GLN A 1 101 ? -6.92593  8.62182   14.92845  1.000 19.54378  ? 93  GLN A HG2  1 
ATOM   1563 H HG3  . GLN A 1 101 ? -7.49659  9.62979   16.01646  1.000 19.54378  ? 93  GLN A HG3  1 
ATOM   1564 H HE21 . GLN A 1 101 ? -8.58862  8.48589   12.99818  1.000 29.33891  ? 93  GLN A HE21 1 
ATOM   1565 H HE22 . GLN A 1 101 ? -9.97704  8.13916   13.41156  1.000 29.33891  ? 93  GLN A HE22 1 
ATOM   1566 N N    . THR A 1 102 ? -5.24343  13.34442  13.78263  1.000 16.99967  ? 94  THR A N    1 
ATOM   1567 C CA   . THR A 1 102 ? -4.70351  14.31715  12.83784  1.000 17.48827  ? 94  THR A CA   1 
ATOM   1568 C C    . THR A 1 102 ? -3.19284  14.19864  12.67292  1.000 14.55587  ? 94  THR A C    1 
ATOM   1569 O O    . THR A 1 102 ? -2.63007  14.76879  11.73046  1.000 16.35765  ? 94  THR A O    1 
ATOM   1570 C CB   . THR A 1 102 ? -5.03207  15.74330  13.28264  1.000 15.37656  ? 94  THR A CB   1 
ATOM   1571 O OG1  . THR A 1 102 ? -4.26695  16.09662  14.44383  1.000 13.50156  ? 94  THR A OG1  1 
ATOM   1572 C CG2  . THR A 1 102 ? -6.52663  15.88972  13.57300  1.000 21.32817  ? 94  THR A CG2  1 
ATOM   1573 H H    . THR A 1 102 ? -5.50724  13.68328  14.52773  1.000 20.41663  ? 94  THR A H    1 
ATOM   1574 H HA   . THR A 1 102 ? -5.12703  14.16158  11.97916  1.000 21.00295  ? 94  THR A HA   1 
ATOM   1575 H HB   . THR A 1 102 ? -4.80380  16.35741  12.56734  1.000 18.46890  ? 94  THR A HB   1 
ATOM   1576 H HG1  . THR A 1 102 ? -4.52125  15.64391  15.10412  1.000 16.21889  ? 94  THR A HG1  1 
ATOM   1577 H HG21 . THR A 1 102 ? -6.73579  16.81453  13.77764  1.000 25.61083  ? 94  THR A HG21 1 
ATOM   1578 H HG22 . THR A 1 102 ? -7.04338  15.61374  12.79989  1.000 25.61083  ? 94  THR A HG22 1 
ATOM   1579 H HG23 . THR A 1 102 ? -6.77323  15.33617  14.33041  1.000 25.61083  ? 94  THR A HG23 1 
ATOM   1580 N N    . GLY A 1 103 ? -2.52257  13.50186  13.57520  1.000 13.39882  ? 95  GLY A N    1 
ATOM   1581 C CA   . GLY A 1 103 ? -1.08069  13.48440  13.60753  1.000 14.72946  ? 95  GLY A CA   1 
ATOM   1582 C C    . GLY A 1 103 ? -0.46110  14.61647  14.39411  1.000 13.19007  ? 95  GLY A C    1 
ATOM   1583 O O    . GLY A 1 103 ? 0.73814   14.57071  14.68132  1.000 12.97638  ? 95  GLY A O    1 
ATOM   1584 H H    . GLY A 1 103 ? -2.89111  13.02421  14.18808  1.000 16.09561  ? 95  GLY A H    1 
ATOM   1585 H HA2  . GLY A 1 103 ? -0.78706  12.64971  14.00497  1.000 17.69238  ? 95  GLY A HA2  1 
ATOM   1586 H HA3  . GLY A 1 103 ? -0.74702  13.53579  12.69818  1.000 17.69238  ? 95  GLY A HA3  1 
ATOM   1587 N N    . LYS A 1 104 ? -1.23221  15.62764  14.76424  1.000 12.25204  ? 96  LYS A N    1 
ATOM   1588 C CA   . LYS A 1 104 ? -0.63088  16.81026  15.35633  1.000 13.87932  ? 96  LYS A CA   1 
ATOM   1589 C C    . LYS A 1 104 ? -0.27099  16.62316  16.82036  1.000 12.44477  ? 96  LYS A C    1 
ATOM   1590 O O    . LYS A 1 104 ? 0.44310   17.47137  17.36672  1.000 13.45417  ? 96  LYS A O    1 
ATOM   1591 C CB   . LYS A 1 104 ? -1.57799  18.00602  15.19365  1.000 19.26403  ? 96  LYS A CB   1 
ATOM   1592 C CG   . LYS A 1 104 ? -1.81255  18.44342  13.72580  1.000 25.42265  ? 96  LYS A CG   1 
ATOM   1593 C CD   . LYS A 1 104 ? -0.51946  18.37192  12.89972  1.000 48.89121  ? 96  LYS A CD   1 
ATOM   1594 C CE   . LYS A 1 104 ? -0.81618  18.35858  11.40018  1.000 62.69383  ? 96  LYS A CE   1 
ATOM   1595 N NZ   . LYS A 1 104 ? -0.33289  17.08830  10.72486  1.000 54.02387  ? 96  LYS A NZ   1 
ATOM   1596 H H    . LYS A 1 104 ? -2.08816  15.65293  14.68488  1.000 14.71948  ? 96  LYS A H    1 
ATOM   1597 H HA   . LYS A 1 104 ? 0.19219   17.01395  14.88521  1.000 16.67221  ? 96  LYS A HA   1 
ATOM   1598 H HB2  . LYS A 1 104 ? -2.44017  17.77097  15.57086  1.000 23.13386  ? 96  LYS A HB2  1 
ATOM   1599 H HB3  . LYS A 1 104 ? -1.20336  18.76396  15.66911  1.000 23.13386  ? 96  LYS A HB3  1 
ATOM   1600 H HG2  . LYS A 1 104 ? -2.46761  17.85636  13.31695  1.000 30.52420  ? 96  LYS A HG2  1 
ATOM   1601 H HG3  . LYS A 1 104 ? -2.13267  19.35896  13.71119  1.000 30.52420  ? 96  LYS A HG3  1 
ATOM   1602 H HD2  . LYS A 1 104 ? 0.03055   19.14661  13.09528  1.000 58.68648  ? 96  LYS A HD2  1 
ATOM   1603 H HD3  . LYS A 1 104 ? -0.03937  17.55924  13.12324  1.000 58.68648  ? 96  LYS A HD3  1 
ATOM   1604 H HE2  . LYS A 1 104 ? -1.77448  18.42514  11.26558  1.000 75.24962  ? 96  LYS A HE2  1 
ATOM   1605 H HE3  . LYS A 1 104 ? -0.36930  19.11081  10.98144  1.000 75.24962  ? 96  LYS A HE3  1 
ATOM   1606 H HZ1  . LYS A 1 104 ? -0.49684  17.12685  9.85094   1.000 64.84567  ? 96  LYS A HZ1  1 
ATOM   1607 H HZ2  . LYS A 1 104 ? 0.54282   16.99104  10.85043  1.000 64.84567  ? 96  LYS A HZ2  1 
ATOM   1608 H HZ3  . LYS A 1 104 ? -0.75385  16.38265  11.06685  1.000 64.84567  ? 96  LYS A HZ3  1 
ATOM   1609 N N    . ALA A 1 105 ? -0.78699  15.58125  17.47795  1.000 13.69778  ? 97  ALA A N    1 
ATOM   1610 C CA   . ALA A 1 105 ? -0.33077  15.27713  18.83014  1.000 12.91190  ? 97  ALA A CA   1 
ATOM   1611 C C    . ALA A 1 105 ? 1.15390   14.93618  18.84711  1.000 12.76690  ? 97  ALA A C    1 
ATOM   1612 O O    . ALA A 1 105 ? 1.83718   15.20488  19.84244  1.000 14.65847  ? 97  ALA A O    1 
ATOM   1613 C CB   . ALA A 1 105 ? -1.15241  14.13548  19.42656  1.000 15.09274  ? 97  ALA A CB   1 
ATOM   1614 H H    . ALA A 1 105 ? -1.38778  15.04889  17.16934  1.000 16.45436  ? 97  ALA A H    1 
ATOM   1615 H HA   . ALA A 1 105 ? -0.46847  16.05689  19.39041  1.000 15.51130  ? 97  ALA A HA   1 
ATOM   1616 H HB1  . ALA A 1 105 ? -0.82618  13.94480  20.31993  1.000 18.12831  ? 97  ALA A HB1  1 
ATOM   1617 H HB2  . ALA A 1 105 ? -2.08395  14.40322  19.46473  1.000 18.12831  ? 97  ALA A HB2  1 
ATOM   1618 H HB3  . ALA A 1 105 ? -1.05661  13.35048  18.86488  1.000 18.12831  ? 97  ALA A HB3  1 
ATOM   1619 N N    . ILE A 1 106 ? 1.67443   14.37214  17.74992  1.000 14.45424  ? 98  ILE A N    1 
ATOM   1620 C CA   . ILE A 1 106 ? 3.11423   14.15085  17.63127  1.000 12.79853  ? 98  ILE A CA   1 
ATOM   1621 C C    . ILE A 1 106 ? 3.84603   15.48281  17.67206  1.000 8.79564   ? 98  ILE A C    1 
ATOM   1622 O O    . ILE A 1 106 ? 4.81771   15.65317  18.41523  1.000 12.95231  ? 98  ILE A O    1 
ATOM   1623 C CB   . ILE A 1 106 ? 3.44485   13.37653  16.34208  1.000 12.20960  ? 98  ILE A CB   1 
ATOM   1624 C CG1  . ILE A 1 106 ? 2.74056   12.01811  16.32227  1.000 19.44786  ? 98  ILE A CG1  1 
ATOM   1625 C CG2  . ILE A 1 106 ? 4.94435   13.20231  16.20405  1.000 17.41877  ? 98  ILE A CG2  1 
ATOM   1626 C CD1  . ILE A 1 106 ? 3.03769   11.14960  17.53197  1.000 17.44863  ? 98  ILE A CD1  1 
ATOM   1627 H H    . ILE A 1 106 ? 1.21808   14.11232  17.06887  1.000 17.36212  ? 98  ILE A H    1 
ATOM   1628 H HA   . ILE A 1 106 ? 3.40472   13.61247  18.38404  1.000 15.37526  ? 98  ILE A HA   1 
ATOM   1629 H HB   . ILE A 1 106 ? 3.11917   13.89309  15.58843  1.000 14.66855  ? 98  ILE A HB   1 
ATOM   1630 H HG12 . ILE A 1 106 ? 1.78223   12.16528  16.29320  1.000 23.35445  ? 98  ILE A HG12 1 
ATOM   1631 H HG13 . ILE A 1 106 ? 3.02561   11.53172  15.53292  1.000 23.35445  ? 98  ILE A HG13 1 
ATOM   1632 H HG21 . ILE A 1 106 ? 5.13442   12.75610  15.36401  1.000 20.91955  ? 98  ILE A HG21 1 
ATOM   1633 H HG22 . ILE A 1 106 ? 5.36631   14.07561  16.21761  1.000 20.91955  ? 98  ILE A HG22 1 
ATOM   1634 H HG23 . ILE A 1 106 ? 5.26946   12.66632  16.94427  1.000 20.91955  ? 98  ILE A HG23 1 
ATOM   1635 H HD11 . ILE A 1 106 ? 2.66402   10.26643  17.38610  1.000 20.95537  ? 98  ILE A HD11 1 
ATOM   1636 H HD12 . ILE A 1 106 ? 3.99876   11.08719  17.64752  1.000 20.95537  ? 98  ILE A HD12 1 
ATOM   1637 H HD13 . ILE A 1 106 ? 2.63568   11.55334  18.31701  1.000 20.95537  ? 98  ILE A HD13 1 
ATOM   1638 N N    . ASP A 1 107 ? 3.37880   16.45340  16.87322  1.000 13.78963  ? 99  ASP A N    1 
ATOM   1639 C CA   A ASP A 1 107 ? 3.99587   17.77764  16.87838  0.319 13.52188  ? 99  ASP A CA   1 
ATOM   1640 C CA   B ASP A 1 107 ? 3.99956   17.77376  16.87828  0.681 13.57847  ? 99  ASP A CA   1 
ATOM   1641 C C    . ASP A 1 107 ? 3.97421   18.38327  18.27524  1.000 12.49643  ? 99  ASP A C    1 
ATOM   1642 O O    . ASP A 1 107 ? 4.94980   19.01300  18.70667  1.000 13.13487  ? 99  ASP A O    1 
ATOM   1643 C CB   A ASP A 1 107 ? 3.27706   18.70194  15.89422  0.319 14.77909  ? 99  ASP A CB   1 
ATOM   1644 C CB   B ASP A 1 107 ? 3.29476   18.67814  15.86847  0.681 14.51243  ? 99  ASP A CB   1 
ATOM   1645 C CG   A ASP A 1 107 ? 3.17058   18.11286  14.50413  0.319 24.16996  ? 99  ASP A CG   1 
ATOM   1646 C CG   B ASP A 1 107 ? 3.48792   18.20834  14.43446  0.681 24.35767  ? 99  ASP A CG   1 
ATOM   1647 O OD1  A ASP A 1 107 ? 3.57790   16.94670  14.31583  0.319 21.17992  ? 99  ASP A OD1  1 
ATOM   1648 O OD1  B ASP A 1 107 ? 3.02210   17.09766  14.09660  0.681 23.46819  ? 99  ASP A OD1  1 
ATOM   1649 O OD2  A ASP A 1 107 ? 2.66762   18.82369  13.60409  0.319 18.12141  ? 99  ASP A OD2  1 
ATOM   1650 O OD2  B ASP A 1 107 ? 4.10625   18.94863  13.64034  0.681 24.72006  ? 99  ASP A OD2  1 
ATOM   1651 H H    . ASP A 1 107 ? 2.71672   16.37345  16.33021  1.000 16.56458  ? 99  ASP A H    1 
ATOM   1652 H HA   . ASP A 1 107 ? 4.91863   17.69088  16.59222  1.000 16.31119  ? 99  ASP A HA   1 
ATOM   1653 H HB2  A ASP A 1 107 ? 2.37821   18.86986  16.21790  0.319 17.75193  ? 99  ASP A HB2  1 
ATOM   1654 H HB2  B ASP A 1 107 ? 2.34346   18.68443  16.05792  0.681 17.43194  ? 99  ASP A HB2  1 
ATOM   1655 H HB3  A ASP A 1 107 ? 3.76749   19.53628  15.82907  0.319 17.75193  ? 99  ASP A HB3  1 
ATOM   1656 H HB3  B ASP A 1 107 ? 3.65366   19.57628  15.94221  0.681 17.43194  ? 99  ASP A HB3  1 
ATOM   1657 N N    . PHE A 1 108 ? 2.86939   18.19762  18.99910  1.000 13.32079  ? 100 PHE A N    1 
ATOM   1658 C CA   . PHE A 1 108 ? 2.77944   18.69686  20.36517  1.000 14.45990  ? 100 PHE A CA   1 
ATOM   1659 C C    . PHE A 1 108 ? 3.84980   18.06945  21.24730  1.000 14.85954  ? 100 PHE A C    1 
ATOM   1660 O O    . PHE A 1 108 ? 4.53446   18.76941  21.99737  1.000 12.58640  ? 100 PHE A O    1 
ATOM   1661 C CB   . PHE A 1 108 ? 1.38804   18.42393  20.94234  1.000 12.59500  ? 100 PHE A CB   1 
ATOM   1662 C CG   . PHE A 1 108 ? 1.28865   18.69130  22.42027  1.000 13.08907  ? 100 PHE A CG   1 
ATOM   1663 C CD1  . PHE A 1 108 ? 0.92975   19.94651  22.88409  1.000 20.25788  ? 100 PHE A CD1  1 
ATOM   1664 C CD2  . PHE A 1 108 ? 1.56563   17.69333  23.34904  1.000 13.22736  ? 100 PHE A CD2  1 
ATOM   1665 C CE1  . PHE A 1 108 ? 0.85634   20.20609  24.23659  1.000 17.98519  ? 100 PHE A CE1  1 
ATOM   1666 C CE2  . PHE A 1 108 ? 1.47733   17.94982  24.70699  1.000 15.95842  ? 100 PHE A CE2  1 
ATOM   1667 C CZ   . PHE A 1 108 ? 1.12552   19.21718  25.14459  1.000 16.67344  ? 100 PHE A CZ   1 
ATOM   1668 H H    . PHE A 1 108 ? 2.16486   17.78894  18.72300  1.000 16.00197  ? 100 PHE A H    1 
ATOM   1669 H HA   . PHE A 1 108 ? 2.91602   19.65709  20.35088  1.000 17.36890  ? 100 PHE A HA   1 
ATOM   1670 H HB2  . PHE A 1 108 ? 0.74539   18.99498  20.49313  1.000 15.13102  ? 100 PHE A HB2  1 
ATOM   1671 H HB3  . PHE A 1 108 ? 1.16475   17.49183  20.79327  1.000 15.13102  ? 100 PHE A HB3  1 
ATOM   1672 H HD1  . PHE A 1 108 ? 0.73588   20.62263  22.27566  1.000 24.32647  ? 100 PHE A HD1  1 
ATOM   1673 H HD2  . PHE A 1 108 ? 1.81236   16.84615  23.05526  1.000 15.88985  ? 100 PHE A HD2  1 
ATOM   1674 H HE1  . PHE A 1 108 ? 0.62311   21.05615  24.53308  1.000 21.59925  ? 100 PHE A HE1  1 
ATOM   1675 H HE2  . PHE A 1 108 ? 1.65321   17.27509  25.32237  1.000 19.16713  ? 100 PHE A HE2  1 
ATOM   1676 H HZ   . PHE A 1 108 ? 1.07225   19.39595  26.05569  1.000 20.02516  ? 100 PHE A HZ   1 
ATOM   1677 N N    . ILE A 1 109 ? 4.01850   16.74620  21.16162  1.000 10.33319  ? 101 ILE A N    1 
ATOM   1678 C CA   . ILE A 1 109 ? 5.01335   16.07042  21.99631  1.000 11.71182  ? 101 ILE A CA   1 
ATOM   1679 C C    . ILE A 1 109 ? 6.41930   16.52261  21.63058  1.000 15.25860  ? 101 ILE A C    1 
ATOM   1680 O O    . ILE A 1 109 ? 7.27161   16.71943  22.50580  1.000 14.89317  ? 101 ILE A O    1 
ATOM   1681 C CB   . ILE A 1 109 ? 4.87234   14.54555  21.86640  1.000 12.12230  ? 101 ILE A CB   1 
ATOM   1682 C CG1  . ILE A 1 109 ? 3.54079   14.08276  22.46730  1.000 9.84356   ? 101 ILE A CG1  1 
ATOM   1683 C CG2  . ILE A 1 109 ? 6.03255   13.83446  22.56326  1.000 16.19029  ? 101 ILE A CG2  1 
ATOM   1684 C CD1  . ILE A 1 109 ? 3.20655   12.63671  22.15732  1.000 14.98102  ? 101 ILE A CD1  1 
ATOM   1685 H H    . ILE A 1 109 ? 3.57737   16.22635  20.63744  1.000 12.41685  ? 101 ILE A H    1 
ATOM   1686 H HA   . ILE A 1 109 ? 4.84837   16.31600  22.92009  1.000 14.07120  ? 101 ILE A HA   1 
ATOM   1687 H HB   . ILE A 1 109 ? 4.89014   14.32090  20.92294  1.000 14.56378  ? 101 ILE A HB   1 
ATOM   1688 H HG12 . ILE A 1 109 ? 3.58316   14.17761  23.43172  1.000 11.82929  ? 101 ILE A HG12 1 
ATOM   1689 H HG13 . ILE A 1 109 ? 2.82787   14.63539  22.11059  1.000 11.82929  ? 101 ILE A HG13 1 
ATOM   1690 H HG21 . ILE A 1 109 ? 5.84971   12.88219  22.58880  1.000 19.44537  ? 101 ILE A HG21 1 
ATOM   1691 H HG22 . ILE A 1 109 ? 6.84907   14.00131  22.06692  1.000 19.44537  ? 101 ILE A HG22 1 
ATOM   1692 H HG23 . ILE A 1 109 ? 6.11784   14.17923  23.46590  1.000 19.44537  ? 101 ILE A HG23 1 
ATOM   1693 H HD11 . ILE A 1 109 ? 2.30536   12.44841  22.46277  1.000 17.99425  ? 101 ILE A HD11 1 
ATOM   1694 H HD12 . ILE A 1 109 ? 3.26709   12.49694  21.19936  1.000 17.99425  ? 101 ILE A HD12 1 
ATOM   1695 H HD13 . ILE A 1 109 ? 3.83834   12.06120  22.61615  1.000 17.99425  ? 101 ILE A HD13 1 
ATOM   1696 N N    . MET A 1 110 ? 6.69227   16.66460  20.33373  1.000 14.46863  ? 102 MET A N    1 
ATOM   1697 C CA   . MET A 1 110 ? 7.99614   17.14820  19.89657  1.000 11.87668  ? 102 MET A CA   1 
ATOM   1698 C C    . MET A 1 110 ? 8.34677   18.46550  20.57710  1.000 15.90490  ? 102 MET A C    1 
ATOM   1699 O O    . MET A 1 110 ? 9.47309   18.65838  21.04823  1.000 18.06197  ? 102 MET A O    1 
ATOM   1700 C CB   . MET A 1 110 ? 8.00034   17.30952  18.37756  1.000 14.28228  ? 102 MET A CB   1 
ATOM   1701 C CG   . MET A 1 110 ? 8.01941   16.01475  17.60120  1.000 14.02016  ? 102 MET A CG   1 
ATOM   1702 S SD   . MET A 1 110 ? 7.60696   16.28745  15.85241  1.000 15.56877  ? 102 MET A SD   1 
ATOM   1703 C CE   . MET A 1 110 ? 8.88639   17.47021  15.39157  1.000 20.78106  ? 102 MET A CE   1 
ATOM   1704 H H    . MET A 1 110 ? 6.14438   16.48921  19.69447  1.000 17.37938  ? 102 MET A H    1 
ATOM   1705 H HA   . MET A 1 110 ? 8.66864   16.48932  20.13007  1.000 14.26904  ? 102 MET A HA   1 
ATOM   1706 H HB2  . MET A 1 110 ? 7.20080   17.79332  18.11759  1.000 17.15575  ? 102 MET A HB2  1 
ATOM   1707 H HB3  . MET A 1 110 ? 8.78982   17.81285  18.12405  1.000 17.15575  ? 102 MET A HB3  1 
ATOM   1708 H HG2  . MET A 1 110 ? 8.90587   15.62390  17.64930  1.000 16.84122  ? 102 MET A HG2  1 
ATOM   1709 H HG3  . MET A 1 110 ? 7.36670   15.40412  17.97803  1.000 16.84122  ? 102 MET A HG3  1 
ATOM   1710 H HE1  . MET A 1 110 ? 8.80777   17.66771  14.44515  1.000 24.95429  ? 102 MET A HE1  1 
ATOM   1711 H HE2  . MET A 1 110 ? 8.76782   18.28158  15.90975  1.000 24.95429  ? 102 MET A HE2  1 
ATOM   1712 H HE3  . MET A 1 110 ? 9.75612   17.08308  15.57756  1.000 24.95429  ? 102 MET A HE3  1 
ATOM   1713 N N    . ALA A 1 111 ? 7.39020   19.39587  20.61447  1.000 16.25535  ? 103 ALA A N    1 
ATOM   1714 C CA   . ALA A 1 111 ? 7.65564   20.70734  21.18891  1.000 18.20522  ? 103 ALA A CA   1 
ATOM   1715 C C    . ALA A 1 111 ? 7.75218   20.62836  22.70250  1.000 20.38994  ? 103 ALA A C    1 
ATOM   1716 O O    . ALA A 1 111 ? 8.64241   21.23986  23.30681  1.000 19.34062  ? 103 ALA A O    1 
ATOM   1717 C CB   . ALA A 1 111 ? 6.55692   21.68593  20.77301  1.000 18.89317  ? 103 ALA A CB   1 
ATOM   1718 H H    . ALA A 1 111 ? 6.59014   19.29135  20.31686  1.000 19.52344  ? 103 ALA A H    1 
ATOM   1719 H HA   . ALA A 1 111 ? 8.50136   21.03855  20.84838  1.000 21.86329  ? 103 ALA A HA   1 
ATOM   1720 H HB1  . ALA A 1 111 ? 6.73614   22.55089  21.17380  1.000 22.68882  ? 103 ALA A HB1  1 
ATOM   1721 H HB2  . ALA A 1 111 ? 6.55281   21.76383  19.80616  1.000 22.68882  ? 103 ALA A HB2  1 
ATOM   1722 H HB3  . ALA A 1 111 ? 5.70102   21.34943  21.08139  1.000 22.68882  ? 103 ALA A HB3  1 
ATOM   1723 N N    . ALA A 1 112 ? 6.85707   19.85627  23.32773  1.000 15.56002  ? 104 ALA A N    1 
ATOM   1724 C CA   . ALA A 1 112 ? 6.83992   19.76306  24.78579  1.000 18.91015  ? 104 ALA A CA   1 
ATOM   1725 C C    . ALA A 1 112 ? 8.12176   19.14839  25.33755  1.000 20.28966  ? 104 ALA A C    1 
ATOM   1726 O O    . ALA A 1 112 ? 8.63105   19.59023  26.37703  1.000 19.58574  ? 104 ALA A O    1 
ATOM   1727 C CB   . ALA A 1 112 ? 5.63069   18.95195  25.24999  1.000 17.99534  ? 104 ALA A CB   1 
ATOM   1728 H H    . ALA A 1 112 ? 6.25687   19.38263  22.93399  1.000 18.68905  ? 104 ALA A H    1 
ATOM   1729 H HA   . ALA A 1 112 ? 6.76456   20.66300  25.13981  1.000 22.70921  ? 104 ALA A HA   1 
ATOM   1730 H HB1  . ALA A 1 112 ? 5.64702   18.88637  26.21764  1.000 21.61144  ? 104 ALA A HB1  1 
ATOM   1731 H HB2  . ALA A 1 112 ? 4.82021   19.40068  24.96249  1.000 21.61144  ? 104 ALA A HB2  1 
ATOM   1732 H HB3  . ALA A 1 112 ? 5.67523   18.06597  24.85761  1.000 21.61144  ? 104 ALA A HB3  1 
ATOM   1733 N N    . LEU A 1 113 ? 8.65856   18.13421  24.66388  1.000 16.65082  ? 105 LEU A N    1 
ATOM   1734 C CA   . LEU A 1 113 ? 9.83740   17.42185  25.13398  1.000 18.27659  ? 105 LEU A CA   1 
ATOM   1735 C C    . LEU A 1 113 ? 11.10714  17.79328  24.38185  1.000 19.42297  ? 105 LEU A C    1 
ATOM   1736 O O    . LEU A 1 113 ? 12.17198  17.22960  24.67453  1.000 16.49493  ? 105 LEU A O    1 
ATOM   1737 C CB   . LEU A 1 113 ? 9.60405   15.91456  25.02933  1.000 19.53257  ? 105 LEU A CB   1 
ATOM   1738 C CG   . LEU A 1 113 ? 8.38261   15.41076  25.80439  1.000 26.43966  ? 105 LEU A CG   1 
ATOM   1739 C CD1  . LEU A 1 113 ? 8.28647   13.89947  25.68488  1.000 20.87484  ? 105 LEU A CD1  1 
ATOM   1740 C CD2  . LEU A 1 113 ? 8.44607   15.83782  27.25440  1.000 21.11518  ? 105 LEU A CD2  1 
ATOM   1741 H H    . LEU A 1 113 ? 8.35027   17.83664  23.91822  1.000 19.99801  ? 105 LEU A H    1 
ATOM   1742 H HA   . LEU A 1 113 ? 9.97907   17.64572  26.06710  1.000 21.94893  ? 105 LEU A HA   1 
ATOM   1743 H HB2  . LEU A 1 113 ? 9.47522   15.68583  24.09553  1.000 23.45611  ? 105 LEU A HB2  1 
ATOM   1744 H HB3  . LEU A 1 113 ? 10.38419  15.45602  25.37864  1.000 23.45611  ? 105 LEU A HB3  1 
ATOM   1745 H HG   . LEU A 1 113 ? 7.57880   15.80067  25.42653  1.000 31.74461  ? 105 LEU A HG   1 
ATOM   1746 H HD11 . LEU A 1 113 ? 7.53648   13.58782  26.21526  1.000 25.06683  ? 105 LEU A HD11 1 
ATOM   1747 H HD12 . LEU A 1 113 ? 8.15328   13.66418  24.75333  1.000 25.06683  ? 105 LEU A HD12 1 
ATOM   1748 H HD13 . LEU A 1 113 ? 9.10968   13.50385  26.01154  1.000 25.06683  ? 105 LEU A HD13 1 
ATOM   1749 H HD21 . LEU A 1 113 ? 7.73797   15.39296  27.74592  1.000 25.35524  ? 105 LEU A HD21 1 
ATOM   1750 H HD22 . LEU A 1 113 ? 9.30939   15.58838  27.61959  1.000 25.35524  ? 105 LEU A HD22 1 
ATOM   1751 H HD23 . LEU A 1 113 ? 8.33060   16.79956  27.30570  1.000 25.35524  ? 105 LEU A HD23 1 
ATOM   1752 N N    . GLU A 1 114 ? 11.01581  18.71495  23.42456  1.000 17.05101  ? 106 GLU A N    1 
ATOM   1753 C CA   . GLU A 1 114 ? 12.14399  19.14912  22.60288  1.000 15.89159  ? 106 GLU A CA   1 
ATOM   1754 C C    . GLU A 1 114 ? 12.83203  17.95224  21.94794  1.000 21.23947  ? 106 GLU A C    1 
ATOM   1755 O O    . GLU A 1 114 ? 14.03720  17.72349  22.09862  1.000 18.37041  ? 106 GLU A O    1 
ATOM   1756 C CB   . GLU A 1 114 ? 13.12722  19.97707  23.43330  1.000 20.74952  ? 106 GLU A CB   1 
ATOM   1757 C CG   . GLU A 1 114 ? 12.54167  21.28786  23.94175  1.000 31.20652  ? 106 GLU A CG   1 
ATOM   1758 C CD   . GLU A 1 114 ? 12.08900  22.20873  22.81739  1.000 57.07684  ? 106 GLU A CD   1 
ATOM   1759 O OE1  . GLU A 1 114 ? 12.63814  22.10041  21.69879  1.000 64.04616  ? 106 GLU A OE1  1 
ATOM   1760 O OE2  . GLU A 1 114 ? 11.18429  23.04212  23.05132  1.000 51.35342  ? 106 GLU A OE2  1 
ATOM   1761 H H    . GLU A 1 114 ? 10.28304  19.11839  23.22484  1.000 20.47823  ? 106 GLU A H    1 
ATOM   1762 H HA   . GLU A 1 114 ? 11.80780  19.71299  21.88878  1.000 19.08693  ? 106 GLU A HA   1 
ATOM   1763 H HB2  . GLU A 1 114 ? 13.40180  19.45579  24.20387  1.000 24.91645  ? 106 GLU A HB2  1 
ATOM   1764 H HB3  . GLU A 1 114 ? 13.89837  20.18938  22.88452  1.000 24.91645  ? 106 GLU A HB3  1 
ATOM   1765 H HG2  . GLU A 1 114 ? 11.77157  21.09454  24.49896  1.000 37.46484  ? 106 GLU A HG2  1 
ATOM   1766 H HG3  . GLU A 1 114 ? 13.21619  21.75550  24.45869  1.000 37.46484  ? 106 GLU A HG3  1 
ATOM   1767 N N    . LEU A 1 115 ? 12.03086  17.18968  21.20255  1.000 17.42700  ? 107 LEU A N    1 
ATOM   1768 C CA   . LEU A 1 115 ? 12.50862  16.02631  20.47432  1.000 18.01745  ? 107 LEU A CA   1 
ATOM   1769 C C    . LEU A 1 115 ? 12.21289  16.16052  18.98726  1.000 18.04389  ? 107 LEU A C    1 
ATOM   1770 O O    . LEU A 1 115 ? 11.22851  16.78682  18.58555  1.000 17.36399  ? 107 LEU A O    1 
ATOM   1771 C CB   . LEU A 1 115 ? 11.85291  14.75168  21.01135  1.000 14.61007  ? 107 LEU A CB   1 
ATOM   1772 C CG   . LEU A 1 115 ? 12.15142  14.40484  22.47681  1.000 14.16262  ? 107 LEU A CG   1 
ATOM   1773 C CD1  . LEU A 1 115 ? 11.29196  13.21424  22.91610  1.000 22.72597  ? 107 LEU A CD1  1 
ATOM   1774 C CD2  . LEU A 1 115 ? 13.62873  14.10253  22.66748  1.000 16.29970  ? 107 LEU A CD2  1 
ATOM   1775 H H    . LEU A 1 115 ? 11.18872  17.33383  21.10445  1.000 20.92942  ? 107 LEU A H    1 
ATOM   1776 H HA   . LEU A 1 115 ? 13.47091  15.95828  20.57561  1.000 21.63796  ? 107 LEU A HA   1 
ATOM   1777 H HB2  . LEU A 1 115 ? 10.89128  14.84931  20.92985  1.000 17.54910  ? 107 LEU A HB2  1 
ATOM   1778 H HB3  . LEU A 1 115 ? 12.15746  14.00510  20.47213  1.000 17.54910  ? 107 LEU A HB3  1 
ATOM   1779 H HG   . LEU A 1 115 ? 11.93299  15.16499  23.03838  1.000 17.01217  ? 107 LEU A HG   1 
ATOM   1780 H HD11 . LEU A 1 115 ? 11.47659  13.01825  23.84798  1.000 27.28818  ? 107 LEU A HD11 1 
ATOM   1781 H HD12 . LEU A 1 115 ? 10.35576  13.44264  22.80532  1.000 27.28818  ? 107 LEU A HD12 1 
ATOM   1782 H HD13 . LEU A 1 115 ? 11.51226  12.44590  22.36654  1.000 27.28818  ? 107 LEU A HD13 1 
ATOM   1783 H HD21 . LEU A 1 115 ? 13.78380  13.85617  23.59277  1.000 19.57666  ? 107 LEU A HD21 1 
ATOM   1784 H HD22 . LEU A 1 115 ? 13.87899  13.36949  22.08360  1.000 19.57666  ? 107 LEU A HD22 1 
ATOM   1785 H HD23 . LEU A 1 115 ? 14.14422  14.89350  22.44492  1.000 19.57666  ? 107 LEU A HD23 1 
ATOM   1786 N N    . LYS A 1 116 ? 13.07583  15.55783  18.17194  1.000 14.25624  ? 108 LYS A N    1 
ATOM   1787 C CA   . LYS A 1 116 ? 12.80234  15.40589  16.75103  1.000 16.20748  ? 108 LYS A CA   1 
ATOM   1788 C C    . LYS A 1 116 ? 11.74642  14.32817  16.51081  1.000 15.37024  ? 108 LYS A C    1 
ATOM   1789 O O    . LYS A 1 116 ? 11.53462  13.43156  17.32826  1.000 16.34825  ? 108 LYS A O    1 
ATOM   1790 C CB   . LYS A 1 116 ? 14.07843  15.03179  15.99777  1.000 18.89456  ? 108 LYS A CB   1 
ATOM   1791 C CG   . LYS A 1 116 ? 15.25925  15.96457  16.25453  1.000 24.37709  ? 108 LYS A CG   1 
ATOM   1792 C CD   . LYS A 1 116 ? 16.34374  15.79768  15.17747  1.000 38.58684  ? 108 LYS A CD   1 
ATOM   1793 C CE   . LYS A 1 116 ? 16.97579  14.41228  15.20902  1.000 58.42873  ? 108 LYS A CE   1 
ATOM   1794 N NZ   . LYS A 1 116 ? 17.38692  13.94365  13.84183  1.000 52.41770  ? 108 LYS A NZ   1 
ATOM   1795 H H    . LYS A 1 116 ? 13.82995  15.22738  18.42036  1.000 17.12451  ? 108 LYS A H    1 
ATOM   1796 H HA   . LYS A 1 116 ? 12.46892  16.24832  16.40456  1.000 19.46600  ? 108 LYS A HA   1 
ATOM   1797 H HB2  . LYS A 1 116 ? 14.34591  14.13908  16.26687  1.000 22.69050  ? 108 LYS A HB2  1 
ATOM   1798 H HB3  . LYS A 1 116 ? 13.89216  15.04956  15.04599  1.000 22.69050  ? 108 LYS A HB3  1 
ATOM   1799 H HG2  . LYS A 1 116 ? 14.95247  16.88467  16.24012  1.000 29.26953  ? 108 LYS A HG2  1 
ATOM   1800 H HG3  . LYS A 1 116 ? 15.65090  15.75893  17.11780  1.000 29.26953  ? 108 LYS A HG3  1 
ATOM   1801 H HD2  . LYS A 1 116 ? 15.94669  15.92877  14.30221  1.000 46.32123  ? 108 LYS A HD2  1 
ATOM   1802 H HD3  . LYS A 1 116 ? 17.04376  16.45258  15.32567  1.000 46.32123  ? 108 LYS A HD3  1 
ATOM   1803 H HE2  . LYS A 1 116 ? 17.76637  14.43579  15.77055  1.000 70.13150  ? 108 LYS A HE2  1 
ATOM   1804 H HE3  . LYS A 1 116 ? 16.33443  13.77784  15.56546  1.000 70.13150  ? 108 LYS A HE3  1 
ATOM   1805 H HZ1  . LYS A 1 116 ? 17.38368  13.05418  13.81118  1.000 62.91826  ? 108 LYS A HZ1  1 
ATOM   1806 H HZ2  . LYS A 1 116 ? 16.82088  14.25580  13.23006  1.000 62.91826  ? 108 LYS A HZ2  1 
ATOM   1807 H HZ3  . LYS A 1 116 ? 18.20608  14.23616  13.65335  1.000 62.91826  ? 108 LYS A HZ3  1 
ATOM   1808 N N    . ARG A 1 117 ? 11.11937  14.39511  15.33722  1.000 15.05447  ? 109 ARG A N    1 
ATOM   1809 C CA   . ARG A 1 117 ? 10.05294  13.45524  15.00304  1.000 15.12580  ? 109 ARG A CA   1 
ATOM   1810 C C    . ARG A 1 117 ? 10.54812  12.01563  15.03215  1.000 14.49590  ? 109 ARG A C    1 
ATOM   1811 O O    . ARG A 1 117 ? 9.88085   11.12696  15.58226  1.000 17.21948  ? 109 ARG A O    1 
ATOM   1812 C CB   . ARG A 1 117 ? 9.47931   13.79055  13.62847  1.000 16.37676  ? 109 ARG A CB   1 
ATOM   1813 C CG   . ARG A 1 117 ? 8.12840   13.14817  13.35143  1.000 19.97254  ? 109 ARG A CG   1 
ATOM   1814 C CD   . ARG A 1 117 ? 7.51797   13.65978  12.05108  1.000 16.66170  ? 109 ARG A CD   1 
ATOM   1815 N NE   . ARG A 1 117 ? 7.37166   15.11242  12.05690  1.000 18.01477  ? 109 ARG A NE   1 
ATOM   1816 C CZ   . ARG A 1 117 ? 6.31744   15.76478  12.53728  1.000 19.55857  ? 109 ARG A CZ   1 
ATOM   1817 N NH1  . ARG A 1 117 ? 5.28677   15.10975  13.04159  1.000 16.17969  ? 109 ARG A NH1  1 
ATOM   1818 N NH2  . ARG A 1 117 ? 6.28600   17.08352  12.50444  1.000 18.40739  ? 109 ARG A NH2  1 
ATOM   1819 H H    . ARG A 1 117 ? 11.29095  14.97071  14.72171  1.000 18.08238  ? 109 ARG A H    1 
ATOM   1820 H HA   . ARG A 1 117 ? 9.34749   13.54252  15.66305  1.000 18.16799  ? 109 ARG A HA   1 
ATOM   1821 H HB2  . ARG A 1 117 ? 9.36834   14.75199  13.56354  1.000 19.66914  ? 109 ARG A HB2  1 
ATOM   1822 H HB3  . ARG A 1 117 ? 10.09857  13.48142  12.94886  1.000 19.66914  ? 109 ARG A HB3  1 
ATOM   1823 H HG2  . ARG A 1 117 ? 8.23920   12.18731  13.27808  1.000 23.98407  ? 109 ARG A HG2  1 
ATOM   1824 H HG3  . ARG A 1 117 ? 7.51904   13.35746  14.07653  1.000 23.98407  ? 109 ARG A HG3  1 
ATOM   1825 H HD2  . ARG A 1 117 ? 8.09321   13.41513  11.30936  1.000 20.01106  ? 109 ARG A HD2  1 
ATOM   1826 H HD3  . ARG A 1 117 ? 6.63927   13.26619  11.93329  1.000 20.01106  ? 109 ARG A HD3  1 
ATOM   1827 H HE   . ARG A 1 117 ? 8.01337   15.57959  11.72589  1.000 21.63475  ? 109 ARG A HE   1 
ATOM   1828 H HH11 . ARG A 1 117 ? 5.29201   14.25001  13.06217  1.000 19.43265  ? 109 ARG A HH11 1 
ATOM   1829 H HH12 . ARG A 1 117 ? 4.61067   15.54313  13.34927  1.000 19.43265  ? 109 ARG A HH12 1 
ATOM   1830 H HH21 . ARG A 1 117 ? 6.94753   17.52128  12.17225  1.000 22.10589  ? 109 ARG A HH21 1 
ATOM   1831 H HH22 . ARG A 1 117 ? 5.60398   17.50526  12.81523  1.000 22.10589  ? 109 ARG A HH22 1 
ATOM   1832 N N    . ASN A 1 118 ? 11.71899  11.76203  14.44106  1.000 13.51677  ? 110 ASN A N    1 
ATOM   1833 C CA   . ASN A 1 118 ? 12.25824  10.41427  14.38302  1.000 13.61755  ? 110 ASN A CA   1 
ATOM   1834 C C    . ASN A 1 118 ? 13.16860  10.10617  15.55649  1.000 13.21941  ? 110 ASN A C    1 
ATOM   1835 O O    . ASN A 1 118 ? 14.00855  9.20273   15.46294  1.000 15.86487  ? 110 ASN A O    1 
ATOM   1836 C CB   . ASN A 1 118 ? 12.97047  10.16920  13.05129  1.000 16.49545  ? 110 ASN A CB   1 
ATOM   1837 C CG   . ASN A 1 118 ? 14.22799  10.95643  12.89971  1.000 22.05811  ? 110 ASN A CG   1 
ATOM   1838 O OD1  . ASN A 1 118 ? 14.38420  12.02767  13.47913  1.000 21.77355  ? 110 ASN A OD1  1 
ATOM   1839 N ND2  . ASN A 1 118 ? 15.14927  10.42632  12.09948  1.000 22.83736  ? 110 ASN A ND2  1 
ATOM   1840 H H    . ASN A 1 118 ? 12.21412  12.35849  14.06867  1.000 16.23715  ? 110 ASN A H    1 
ATOM   1841 H HA   . ASN A 1 118 ? 11.51868  9.78757   14.41758  1.000 16.35809  ? 110 ASN A HA   1 
ATOM   1842 H HB2  . ASN A 1 118 ? 13.19868  9.22870   12.98592  1.000 19.81157  ? 110 ASN A HB2  1 
ATOM   1843 H HB3  . ASN A 1 118 ? 12.37516  10.41727  12.32675  1.000 19.81157  ? 110 ASN A HB3  1 
ATOM   1844 H HD21 . ASN A 1 118 ? 15.89543  10.83478  11.97302  1.000 27.42186  ? 110 ASN A HD21 1 
ATOM   1845 H HD22 . ASN A 1 118 ? 14.99860  9.67520   11.70869  1.000 27.42186  ? 110 ASN A HD22 1 
ATOM   1846 N N    . GLU A 1 119 ? 12.99978  10.81939  16.66936  1.000 10.89396  ? 111 GLU A N    1 
ATOM   1847 C CA   . GLU A 1 119 ? 13.52524  10.40039  17.95994  1.000 11.14897  ? 111 GLU A CA   1 
ATOM   1848 C C    . GLU A 1 119 ? 12.44983  9.70228   18.78773  1.000 13.40534  ? 111 GLU A C    1 
ATOM   1849 O O    . GLU A 1 119 ? 12.66682  9.41671   19.96649  1.000 10.78189  ? 111 GLU A O    1 
ATOM   1850 C CB   . GLU A 1 119 ? 14.11214  11.59581  18.72302  1.000 14.17052  ? 111 GLU A CB   1 
ATOM   1851 C CG   . GLU A 1 119 ? 15.46680  12.01859  18.18640  1.000 18.40801  ? 111 GLU A CG   1 
ATOM   1852 C CD   . GLU A 1 119 ? 16.02956  13.28142  18.83544  1.000 22.47217  ? 111 GLU A CD   1 
ATOM   1853 O OE1  . GLU A 1 119 ? 15.24761  14.13432  19.29541  1.000 18.83986  ? 111 GLU A OE1  1 
ATOM   1854 O OE2  . GLU A 1 119 ? 17.27587  13.42435  18.86545  1.000 18.91809  ? 111 GLU A OE2  1 
ATOM   1855 H H    . GLU A 1 119 ? 12.57409  11.56606  16.69893  1.000 13.08977  ? 111 GLU A H    1 
ATOM   1856 H HA   . GLU A 1 119 ? 14.25865  9.78040   17.82347  1.000 13.39579  ? 111 GLU A HA   1 
ATOM   1857 H HB2  . GLU A 1 119 ? 13.50750  12.35011  18.64333  1.000 17.02164  ? 111 GLU A HB2  1 
ATOM   1858 H HB3  . GLU A 1 119 ? 14.21963  11.35393  19.65621  1.000 17.02164  ? 111 GLU A HB3  1 
ATOM   1859 H HG2  . GLU A 1 119 ? 16.10041  11.30076  18.34183  1.000 22.10663  ? 111 GLU A HG2  1 
ATOM   1860 H HG3  . GLU A 1 119 ? 15.38486  12.18855  17.23492  1.000 22.10663  ? 111 GLU A HG3  1 
ATOM   1861 N N    . MET A 1 120 ? 11.29284  9.42017   18.19175  1.000 13.60648  ? 112 MET A N    1 
ATOM   1862 C CA   . MET A 1 120 ? 10.21434  8.73279   18.88108  1.000 10.71933  ? 112 MET A CA   1 
ATOM   1863 C C    . MET A 1 120 ? 9.62038   7.68591   17.95884  1.000 9.29788   ? 112 MET A C    1 
ATOM   1864 O O    . MET A 1 120 ? 9.69303   7.80330   16.72900  1.000 11.74436  ? 112 MET A O    1 
ATOM   1865 C CB   . MET A 1 120 ? 9.11900   9.70464   19.33608  1.000 11.58292  ? 112 MET A CB   1 
ATOM   1866 C CG   . MET A 1 120 ? 9.65368   10.93677  20.03307  1.000 16.38335  ? 112 MET A CG   1 
ATOM   1867 S SD   . MET A 1 120 ? 8.28407   11.95183  20.64506  1.000 27.58468  ? 112 MET A SD   1 
ATOM   1868 C CE   . MET A 1 120 ? 7.24255   11.96106  19.18401  1.000 10.28793  ? 112 MET A CE   1 
ATOM   1869 H H    . MET A 1 120 ? 11.10986  9.62156   17.37593  1.000 16.34480  ? 112 MET A H    1 
ATOM   1870 H HA   . MET A 1 120 ? 10.57060  8.29551   19.67023  1.000 12.88022  ? 112 MET A HA   1 
ATOM   1871 H HB2  . MET A 1 120 ? 8.61829   9.99724   18.55854  1.000 13.91653  ? 112 MET A HB2  1 
ATOM   1872 H HB3  . MET A 1 120 ? 8.53102   9.24483   19.95556  1.000 13.91653  ? 112 MET A HB3  1 
ATOM   1873 H HG2  . MET A 1 120 ? 10.20495  10.67196  20.78598  1.000 19.67705  ? 112 MET A HG2  1 
ATOM   1874 H HG3  . MET A 1 120 ? 10.17619  11.46372  19.40841  1.000 19.67705  ? 112 MET A HG3  1 
ATOM   1875 H HE1  . MET A 1 120 ? 6.54011   12.61968  19.30107  1.000 12.36254  ? 112 MET A HE1  1 
ATOM   1876 H HE2  . MET A 1 120 ? 7.78377   12.18837  18.41180  1.000 12.36254  ? 112 MET A HE2  1 
ATOM   1877 H HE3  . MET A 1 120 ? 6.85383   11.07999  19.06771  1.000 12.36254  ? 112 MET A HE3  1 
ATOM   1878 N N    . ILE A 1 121 ? 9.01718   6.66981   18.58066  1.000 9.58452   ? 113 ILE A N    1 
ATOM   1879 C CA   . ILE A 1 121 ? 8.22159   5.65532   17.90176  1.000 8.87734   ? 113 ILE A CA   1 
ATOM   1880 C C    . ILE A 1 121 ? 6.92435   5.52709   18.68722  1.000 8.20411   ? 113 ILE A C    1 
ATOM   1881 O O    . ILE A 1 121 ? 6.83204   5.96784   19.82969  1.000 9.80772   ? 113 ILE A O    1 
ATOM   1882 C CB   . ILE A 1 121 ? 8.94340   4.29710   17.77995  1.000 9.36925   ? 113 ILE A CB   1 
ATOM   1883 C CG1  . ILE A 1 121 ? 9.14834   3.66928   19.15492  1.000 10.54446  ? 113 ILE A CG1  1 
ATOM   1884 C CG2  . ILE A 1 121 ? 10.26966  4.47412   17.02055  1.000 11.91158  ? 113 ILE A CG2  1 
ATOM   1885 C CD1  . ILE A 1 121 ? 9.97421   2.37618   19.14611  1.000 11.33297  ? 113 ILE A CD1  1 
ATOM   1886 H H    . ILE A 1 121 ? 9.05857   6.54560   19.43063  1.000 11.51845  ? 113 ILE A H    1 
ATOM   1887 H HA   . ILE A 1 121 ? 8.02233   5.93858   16.99569  1.000 10.66984  ? 113 ILE A HA   1 
ATOM   1888 H HB   . ILE A 1 121 ? 8.38704   3.68728   17.27055  1.000 11.26012  ? 113 ILE A HB   1 
ATOM   1889 H HG12 . ILE A 1 121 ? 9.60980   4.30789   19.72071  1.000 12.67038  ? 113 ILE A HG12 1 
ATOM   1890 H HG13 . ILE A 1 121 ? 8.27943   3.45950   19.53162  1.000 12.67038  ? 113 ILE A HG13 1 
ATOM   1891 H HG21 . ILE A 1 121 ? 10.67615  3.60348   16.88772  1.000 14.31092  ? 113 ILE A HG21 1 
ATOM   1892 H HG22 . ILE A 1 121 ? 10.08936  4.88935   16.16266  1.000 14.31092  ? 113 ILE A HG22 1 
ATOM   1893 H HG23 . ILE A 1 121 ? 10.86017  5.03855   17.54363  1.000 14.31092  ? 113 ILE A HG23 1 
ATOM   1894 H HD11 . ILE A 1 121 ? 9.95413   1.98260   20.03245  1.000 13.61658  ? 113 ILE A HD11 1 
ATOM   1895 H HD12 . ILE A 1 121 ? 9.59037   1.76070   18.50210  1.000 13.61658  ? 113 ILE A HD12 1 
ATOM   1896 H HD13 . ILE A 1 121 ? 10.88807  2.58682   18.89835  1.000 13.61658  ? 113 ILE A HD13 1 
ATOM   1897 N N    . TYR A 1 122 ? 5.92419   4.89309   18.06881  1.000 9.06304   ? 114 TYR A N    1 
ATOM   1898 C CA   . TYR A 1 122 ? 4.53987   4.93543   18.54205  1.000 8.66520   ? 114 TYR A CA   1 
ATOM   1899 C C    . TYR A 1 122 ? 3.98389   3.52155   18.56554  1.000 9.34728   ? 114 TYR A C    1 
ATOM   1900 O O    . TYR A 1 122 ? 3.79925   2.90912   17.50981  1.000 10.21562  ? 114 TYR A O    1 
ATOM   1901 C CB   . TYR A 1 122 ? 3.70117   5.82750   17.63251  1.000 10.60279  ? 114 TYR A CB   1 
ATOM   1902 C CG   . TYR A 1 122 ? 2.31546   6.18423   18.11196  1.000 9.08396   ? 114 TYR A CG   1 
ATOM   1903 C CD1  . TYR A 1 122 ? 1.39836   5.20799   18.48296  1.000 11.69768  ? 114 TYR A CD1  1 
ATOM   1904 C CD2  . TYR A 1 122 ? 1.90686   7.50643   18.14904  1.000 11.26510  ? 114 TYR A CD2  1 
ATOM   1905 C CE1  . TYR A 1 122 ? 0.12999   5.54798   18.91412  1.000 13.13765  ? 114 TYR A CE1  1 
ATOM   1906 C CE2  . TYR A 1 122 ? 0.64542   7.84853   18.57021  1.000 9.34442   ? 114 TYR A CE2  1 
ATOM   1907 C CZ   . TYR A 1 122 ? -0.24315  6.87111   18.94425  1.000 10.74185  ? 114 TYR A CZ   1 
ATOM   1908 O OH   . TYR A 1 122 ? -1.51323  7.24951   19.33632  1.000 12.99723  ? 114 TYR A OH   1 
ATOM   1909 H H    . TYR A 1 122 ? 6.02653   4.42153   17.35694  1.000 10.89267  ? 114 TYR A H    1 
ATOM   1910 H HA   . TYR A 1 122 ? 4.51519   5.28097   19.44808  1.000 10.41526  ? 114 TYR A HA   1 
ATOM   1911 H HB2  . TYR A 1 122 ? 4.17996   6.66177   17.50739  1.000 12.74038  ? 114 TYR A HB2  1 
ATOM   1912 H HB3  . TYR A 1 122 ? 3.59723   5.37378   16.78149  1.000 12.74038  ? 114 TYR A HB3  1 
ATOM   1913 H HD1  . TYR A 1 122 ? 1.64211   4.31151   18.44040  1.000 14.05424  ? 114 TYR A HD1  1 
ATOM   1914 H HD2  . TYR A 1 122 ? 2.49697   8.17461   17.88409  1.000 13.53514  ? 114 TYR A HD2  1 
ATOM   1915 H HE1  . TYR A 1 122 ? -0.46669  4.88678   19.18187  1.000 15.78220  ? 114 TYR A HE1  1 
ATOM   1916 H HE2  . TYR A 1 122 ? 0.39284   8.74300   18.60210  1.000 11.23033  ? 114 TYR A HE2  1 
ATOM   1917 H HH   . TYR A 1 122 ? -1.98587  6.56902   19.47468  1.000 15.61370  ? 114 TYR A HH   1 
ATOM   1918 N N    . VAL A 1 123 ? 3.73683   3.00591   19.76636  1.000 10.90271  ? 115 VAL A N    1 
ATOM   1919 C CA   . VAL A 1 123 ? 3.21342   1.65719   19.95614  1.000 9.79536   ? 115 VAL A CA   1 
ATOM   1920 C C    . VAL A 1 123 ? 1.69015   1.73402   20.02431  1.000 10.53272  ? 115 VAL A C    1 
ATOM   1921 O O    . VAL A 1 123 ? 1.12829   2.41494   20.88747  1.000 11.11330  ? 115 VAL A O    1 
ATOM   1922 C CB   . VAL A 1 123 ? 3.78984   1.02334   21.23319  1.000 6.97360   ? 115 VAL A CB   1 
ATOM   1923 C CG1  . VAL A 1 123 ? 3.25394   -0.37632  21.43751  1.000 8.00316   ? 115 VAL A CG1  1 
ATOM   1924 C CG2  . VAL A 1 123 ? 5.30174   0.98954   21.17989  1.000 11.22411  ? 115 VAL A CG2  1 
ATOM   1925 H H    . VAL A 1 123 ? 3.86752   3.42813   20.50410  1.000 13.10028  ? 115 VAL A H    1 
ATOM   1926 H HA   . VAL A 1 123 ? 3.45663   1.10555   19.19624  1.000 11.77145  ? 115 VAL A HA   1 
ATOM   1927 H HB   . VAL A 1 123 ? 3.51598   1.56879   21.98711  1.000 8.38535   ? 115 VAL A HB   1 
ATOM   1928 H HG11 . VAL A 1 123 ? 3.73107   -0.79306  22.17207  1.000 9.62081   ? 115 VAL A HG11 1 
ATOM   1929 H HG12 . VAL A 1 123 ? 2.30765   -0.32508  21.64443  1.000 9.62081   ? 115 VAL A HG12 1 
ATOM   1930 H HG13 . VAL A 1 123 ? 3.38745   -0.88747  20.62400  1.000 9.62081   ? 115 VAL A HG13 1 
ATOM   1931 H HG21 . VAL A 1 123 ? 5.63795   0.59637   22.00042  1.000 13.48596  ? 115 VAL A HG21 1 
ATOM   1932 H HG22 . VAL A 1 123 ? 5.57905   0.45530   20.41924  1.000 13.48596  ? 115 VAL A HG22 1 
ATOM   1933 H HG23 . VAL A 1 123 ? 5.63478   1.89579   21.08663  1.000 13.48596  ? 115 VAL A HG23 1 
ATOM   1934 N N    . GLY A 1 124 ? 1.01519   1.02411   19.12812  1.000 8.58462   ? 116 GLY A N    1 
ATOM   1935 C CA   . GLY A 1 124 ? -0.43561  1.04035   19.13842  1.000 9.37011   ? 116 GLY A CA   1 
ATOM   1936 C C    . GLY A 1 124 ? -0.98612  -0.19742  18.46678  1.000 11.70988  ? 116 GLY A C    1 
ATOM   1937 O O    . GLY A 1 124 ? -0.24046  -1.04479  17.97101  1.000 10.08327  ? 116 GLY A O    1 
ATOM   1938 H H    . GLY A 1 124 ? 1.36984   0.53486   18.51619  1.000 10.31857  ? 116 GLY A H    1 
ATOM   1939 H HA2  . GLY A 1 124 ? -0.75735  1.06921   20.05305  1.000 11.26115  ? 116 GLY A HA2  1 
ATOM   1940 H HA3  . GLY A 1 124 ? -0.75876  1.82295   18.66512  1.000 11.26115  ? 116 GLY A HA3  1 
ATOM   1941 N N    . ARG A 1 125 ? -2.32138  -0.27293  18.42240  1.000 10.46739  ? 117 ARG A N    1 
ATOM   1942 C CA   . ARG A 1 125 ? -3.00257  -1.38770  17.76125  1.000 11.61659  ? 117 ARG A CA   1 
ATOM   1943 C C    . ARG A 1 125 ? -4.24078  -0.94084  16.98349  1.000 9.27994   ? 117 ARG A C    1 
ATOM   1944 O O    . ARG A 1 125 ? -4.50253  -1.43311  15.87559  1.000 11.91258  ? 117 ARG A O    1 
ATOM   1945 C CB   . ARG A 1 125 ? -3.41415  -2.44686  18.78813  1.000 11.46952  ? 117 ARG A CB   1 
ATOM   1946 C CG   . ARG A 1 125 ? -4.27701  -3.59389  18.23744  1.000 11.62611  ? 117 ARG A CG   1 
ATOM   1947 C CD   . ARG A 1 125 ? -3.58304  -4.31503  17.06876  1.000 11.32714  ? 117 ARG A CD   1 
ATOM   1948 N NE   . ARG A 1 125 ? -4.42279  -5.38217  16.50886  1.000 11.28203  ? 117 ARG A NE   1 
ATOM   1949 C CZ   . ARG A 1 125 ? -5.39055  -5.19128  15.61620  1.000 14.80541  ? 117 ARG A CZ   1 
ATOM   1950 N NH1  . ARG A 1 125 ? -5.65391  -3.97376  15.16700  1.000 16.42466  ? 117 ARG A NH1  1 
ATOM   1951 N NH2  . ARG A 1 125 ? -6.11586  -6.21743  15.19033  1.000 17.28639  ? 117 ARG A NH2  1 
ATOM   1952 H H    . ARG A 1 125 ? -2.85270  0.30858   18.76757  1.000 12.57788  ? 117 ARG A H    1 
ATOM   1953 H HA   . ARG A 1 125 ? -2.37773  -1.77245  17.12687  1.000 13.95693  ? 117 ARG A HA   1 
ATOM   1954 H HB2  . ARG A 1 125 ? -2.60980  -2.84187  19.15944  1.000 13.78045  ? 117 ARG A HB2  1 
ATOM   1955 H HB3  . ARG A 1 125 ? -3.92404  -2.01152  19.48913  1.000 13.78045  ? 117 ARG A HB3  1 
ATOM   1956 H HG2  . ARG A 1 125 ? -4.43789  -4.24104  18.94187  1.000 13.96835  ? 117 ARG A HG2  1 
ATOM   1957 H HG3  . ARG A 1 125 ? -5.11968  -3.23606  17.91688  1.000 13.96835  ? 117 ARG A HG3  1 
ATOM   1958 H HD2  . ARG A 1 125 ? -3.39549  -3.67514  16.36430  1.000 13.60959  ? 117 ARG A HD2  1 
ATOM   1959 H HD3  . ARG A 1 125 ? -2.75656  -4.71300  17.38412  1.000 13.60959  ? 117 ARG A HD3  1 
ATOM   1960 H HE   . ARG A 1 125 ? -4.27880  -6.18658  16.77681  1.000 13.55546  ? 117 ARG A HE   1 
ATOM   1961 H HH11 . ARG A 1 125 ? -5.19853  -3.30232  15.45231  1.000 19.72662  ? 117 ARG A HH11 1 
ATOM   1962 H HH12 . ARG A 1 125 ? -6.28032  -3.85448  14.58996  1.000 19.72662  ? 117 ARG A HH12 1 
ATOM   1963 H HH21 . ARG A 1 125 ? -5.96081  -7.00795  15.49138  1.000 20.76069  ? 117 ARG A HH21 1 
ATOM   1964 H HH22 . ARG A 1 125 ? -6.74103  -6.09202  14.61324  1.000 20.76069  ? 117 ARG A HH22 1 
ATOM   1965 N N    . SER A 1 126 ? -5.04335  -0.05770  17.57300  1.000 13.05199  ? 118 SER A N    1 
ATOM   1966 C CA   . SER A 1 126 ? -6.26938  0.35006   16.89874  1.000 12.95670  ? 118 SER A CA   1 
ATOM   1967 C C    . SER A 1 126 ? -5.96463  1.11300   15.60921  1.000 14.57359  ? 118 SER A C    1 
ATOM   1968 O O    . SER A 1 126 ? -4.89603  1.71263   15.43725  1.000 13.26780  ? 118 SER A O    1 
ATOM   1969 C CB   . SER A 1 126 ? -7.13175  1.21312   17.81799  1.000 17.05926  ? 118 SER A CB   1 
ATOM   1970 O OG   . SER A 1 126 ? -6.56265  2.49721   17.94980  1.000 18.60635  ? 118 SER A OG   1 
ATOM   1971 H H    . SER A 1 126 ? -4.90401  0.30794   18.33883  1.000 15.67941  ? 118 SER A H    1 
ATOM   1972 H HA   . SER A 1 126 ? -6.77409  -0.44458  16.66483  1.000 15.56507  ? 118 SER A HA   1 
ATOM   1973 H HB2  . SER A 1 126 ? -8.02010  1.29551   17.43726  1.000 20.48814  ? 118 SER A HB2  1 
ATOM   1974 H HB3  . SER A 1 126 ? -7.18283  0.79563   18.69206  1.000 20.48814  ? 118 SER A HB3  1 
ATOM   1975 H HG   . SER A 1 126 ? -5.86701  2.45638   18.41886  1.000 22.34464  ? 118 SER A HG   1 
ATOM   1976 N N    . GLN A 1 127 ? -6.94027  1.09546   14.68932  1.000 14.29786  ? 119 GLN A N    1 
ATOM   1977 C CA   . GLN A 1 127 ? -6.81724  1.90301   13.48255  1.000 14.27190  ? 119 GLN A CA   1 
ATOM   1978 C C    . GLN A 1 127 ? -6.67660  3.38396   13.81710  1.000 14.35067  ? 119 GLN A C    1 
ATOM   1979 O O    . GLN A 1 127 ? -5.97910  4.11941   13.10540  1.000 14.42922  ? 119 GLN A O    1 
ATOM   1980 C CB   . GLN A 1 127 ? -8.02436  1.67260   12.57328  1.000 18.68733  ? 119 GLN A CB   1 
ATOM   1981 C CG   . GLN A 1 127 ? -8.12816  0.25132   12.03751  1.000 39.04463  ? 119 GLN A CG   1 
ATOM   1982 C CD   . GLN A 1 127 ? -6.83796  -0.24582  11.39794  1.000 52.64414  ? 119 GLN A CD   1 
ATOM   1983 O OE1  . GLN A 1 127 ? -6.34623  0.32659   10.42309  1.000 41.41348  ? 119 GLN A OE1  1 
ATOM   1984 N NE2  . GLN A 1 127 ? -6.28324  -1.31546  11.95167  1.000 35.80846  ? 119 GLN A NE2  1 
ATOM   1985 H H    . GLN A 1 127 ? -7.66382  0.63384   14.74395  1.000 17.17445  ? 119 GLN A H    1 
ATOM   1986 H HA   . GLN A 1 127 ? -6.02297  1.62793   12.99844  1.000 17.14330  ? 119 GLN A HA   1 
ATOM   1987 H HB2  . GLN A 1 127 ? -8.83291  1.85922   13.07560  1.000 22.44182  ? 119 GLN A HB2  1 
ATOM   1988 H HB3  . GLN A 1 127 ? -7.96050  2.27150   11.81293  1.000 22.44182  ? 119 GLN A HB3  1 
ATOM   1989 H HG2  . GLN A 1 127 ? -8.34661  -0.34554  12.77026  1.000 46.87058  ? 119 GLN A HG2  1 
ATOM   1990 H HG3  . GLN A 1 127 ? -8.82583  0.21944   11.36436  1.000 46.87058  ? 119 GLN A HG3  1 
ATOM   1991 H HE21 . GLN A 1 127 ? -6.65302  -1.68752  12.63316  1.000 42.98717  ? 119 GLN A HE21 1 
ATOM   1992 H HE22 . GLN A 1 127 ? -5.55371  -1.63710  11.62928  1.000 42.98717  ? 119 GLN A HE22 1 
ATOM   1993 N N    . GLU A 1 128 ? -7.32132  3.83428   14.89974  1.000 16.21730  ? 120 GLU A N    1 
ATOM   1994 C CA   . GLU A 1 128 ? -7.21099  5.23179   15.30302  1.000 13.95277  ? 120 GLU A CA   1 
ATOM   1995 C C    . GLU A 1 128 ? -5.78218  5.57938   15.70651  1.000 14.08709  ? 120 GLU A C    1 
ATOM   1996 O O    . GLU A 1 128 ? -5.28708  6.66659   15.39688  1.000 14.04812  ? 120 GLU A O    1 
ATOM   1997 C CB   . GLU A 1 128 ? -8.17976  5.51520   16.44871  1.000 14.51891  ? 120 GLU A CB   1 
ATOM   1998 C CG   . GLU A 1 128 ? -9.65456  5.44752   16.04052  1.000 19.53662  ? 120 GLU A CG   1 
ATOM   1999 C CD   . GLU A 1 128 ? -10.18848 4.03408   15.88604  1.000 34.65736  ? 120 GLU A CD   1 
ATOM   2000 O OE1  . GLU A 1 128 ? -9.56355  3.07808   16.39402  1.000 19.04965  ? 120 GLU A OE1  1 
ATOM   2001 O OE2  . GLU A 1 128 ? -11.25431 3.87570   15.25490  1.000 39.78920  ? 120 GLU A OE2  1 
ATOM   2002 H H    . GLU A 1 128 ? -7.82162  3.35469   15.40895  1.000 19.47778  ? 120 GLU A H    1 
ATOM   2003 H HA   . GLU A 1 128 ? -7.45373  5.79806   14.55381  1.000 16.76035  ? 120 GLU A HA   1 
ATOM   2004 H HB2  . GLU A 1 128 ? -8.03570  4.85904   17.14842  1.000 17.43971  ? 120 GLU A HB2  1 
ATOM   2005 H HB3  . GLU A 1 128 ? -8.00739  6.40687   16.78947  1.000 17.43971  ? 120 GLU A HB3  1 
ATOM   2006 H HG2  . GLU A 1 128 ? -10.18631 5.89073   16.72002  1.000 23.46097  ? 120 GLU A HG2  1 
ATOM   2007 H HG3  . GLU A 1 128 ? -9.76273  5.89812   15.18837  1.000 23.46097  ? 120 GLU A HG3  1 
ATOM   2008 N N    . ASP A 1 129 ? -5.09794  4.66323   16.39064  1.000 11.64420  ? 121 ASP A N    1 
ATOM   2009 C CA   . ASP A 1 129 ? -3.70983  4.90314   16.76872  1.000 12.28505  ? 121 ASP A CA   1 
ATOM   2010 C C    . ASP A 1 129 ? -2.75358  4.72395   15.59695  1.000 10.08982  ? 121 ASP A C    1 
ATOM   2011 O O    . ASP A 1 129 ? -1.74806  5.44413   15.51101  1.000 12.73701  ? 121 ASP A O    1 
ATOM   2012 C CB   . ASP A 1 129 ? -3.34528  3.99116   17.93781  1.000 12.99331  ? 121 ASP A CB   1 
ATOM   2013 C CG   . ASP A 1 129 ? -3.94742  4.48167   19.23983  1.000 13.99391  ? 121 ASP A CG   1 
ATOM   2014 O OD1  . ASP A 1 129 ? -3.60841  5.62020   19.63412  1.000 12.98065  ? 121 ASP A OD1  1 
ATOM   2015 O OD2  . ASP A 1 129 ? -4.77097  3.75321   19.83774  1.000 13.63210  ? 121 ASP A OD2  1 
ATOM   2016 H H    . ASP A 1 129 ? -5.41161  3.90380   16.64456  1.000 13.99006  ? 121 ASP A H    1 
ATOM   2017 H HA   . ASP A 1 129 ? -3.60460  5.81971   17.06826  1.000 14.75908  ? 121 ASP A HA   1 
ATOM   2018 H HB2  . ASP A 1 129 ? -3.68162  3.09806   17.76420  1.000 15.60899  ? 121 ASP A HB2  1 
ATOM   2019 H HB3  . ASP A 1 129 ? -2.38071  3.96880   18.03779  1.000 15.60899  ? 121 ASP A HB3  1 
ATOM   2020 N N    . LEU A 1 130 ? -3.05506  3.80893   14.67088  1.000 11.15720  ? 122 LEU A N    1 
ATOM   2021 C CA   . LEU A 1 130 ? -2.27651  3.74191   13.43862  1.000 11.21029  ? 122 LEU A CA   1 
ATOM   2022 C C    . LEU A 1 130 ? -2.33535  5.06697   12.68338  1.000 14.09729  ? 122 LEU A C    1 
ATOM   2023 O O    . LEU A 1 130 ? -1.31457  5.55914   12.19435  1.000 15.41639  ? 122 LEU A O    1 
ATOM   2024 C CB   . LEU A 1 130 ? -2.78232  2.59600   12.56460  1.000 12.55791  ? 122 LEU A CB   1 
ATOM   2025 C CG   . LEU A 1 130 ? -2.19105  2.49415   11.15099  1.000 16.42227  ? 122 LEU A CG   1 
ATOM   2026 C CD1  . LEU A 1 130 ? -0.70156  2.35979   11.16790  1.000 18.80953  ? 122 LEU A CD1  1 
ATOM   2027 C CD2  . LEU A 1 130 ? -2.86541  1.31784   10.42702  1.000 37.27643  ? 122 LEU A CD2  1 
ATOM   2028 H H    . LEU A 1 130 ? -3.68939  3.23147   14.73229  1.000 13.40567  ? 122 LEU A H    1 
ATOM   2029 H HA   . LEU A 1 130 ? -1.34877  3.56209   13.65739  1.000 13.46937  ? 122 LEU A HA   1 
ATOM   2030 H HB2  . LEU A 1 130 ? -2.58117  1.76220   13.01761  1.000 15.08652  ? 122 LEU A HB2  1 
ATOM   2031 H HB3  . LEU A 1 130 ? -3.74195  2.69622   12.46479  1.000 15.08652  ? 122 LEU A HB3  1 
ATOM   2032 H HG   . LEU A 1 130 ? -2.36593  3.31351   10.66216  1.000 19.72375  ? 122 LEU A HG   1 
ATOM   2033 H HD11 . LEU A 1 130 ? -0.36954  2.41056   10.25790  1.000 22.58846  ? 122 LEU A HD11 1 
ATOM   2034 H HD12 . LEU A 1 130 ? -0.32551  3.07994   11.69787  1.000 22.58846  ? 122 LEU A HD12 1 
ATOM   2035 H HD13 . LEU A 1 130 ? -0.46610  1.50376   11.55863  1.000 22.58846  ? 122 LEU A HD13 1 
ATOM   2036 H HD21 . LEU A 1 130 ? -2.45452  1.20602   9.55549   1.000 44.74874  ? 122 LEU A HD21 1 
ATOM   2037 H HD22 . LEU A 1 130 ? -2.74668  0.51249   10.95448  1.000 44.74874  ? 122 LEU A HD22 1 
ATOM   2038 H HD23 . LEU A 1 130 ? -3.81069  1.50998   10.32485  1.000 44.74874  ? 122 LEU A HD23 1 
ATOM   2039 N N    . GLN A 1 131 ? -3.50988  5.69517   12.64045  1.000 14.81420  ? 123 GLN A N    1 
ATOM   2040 C CA   . GLN A 1 131 ? -3.63184  6.97768   11.95852  1.000 13.99503  ? 123 GLN A CA   1 
ATOM   2041 C C    . GLN A 1 131 ? -2.90318  8.07583   12.71515  1.000 13.16890  ? 123 GLN A C    1 
ATOM   2042 O O    . GLN A 1 131 ? -2.24259  8.92569   12.10810  1.000 15.21148  ? 123 GLN A O    1 
ATOM   2043 C CB   . GLN A 1 131 ? -5.10803  7.33049   11.79431  1.000 14.39263  ? 123 GLN A CB   1 
ATOM   2044 C CG   . GLN A 1 131 ? -5.83710  6.44559   10.81705  1.000 22.40587  ? 123 GLN A CG   1 
ATOM   2045 C CD   . GLN A 1 131 ? -7.27142  6.88778   10.59814  1.000 48.15153  ? 123 GLN A CD   1 
ATOM   2046 O OE1  . GLN A 1 131 ? -8.07495  6.16652   10.00565  1.000 46.65272  ? 123 GLN A OE1  1 
ATOM   2047 N NE2  . GLN A 1 131 ? -7.59564  8.08704   11.06381  1.000 45.77621  ? 123 GLN A NE2  1 
ATOM   2048 H H    . GLN A 1 131 ? -4.23847  5.40414   12.99267  1.000 17.79406  ? 123 GLN A H    1 
ATOM   2049 H HA   . GLN A 1 131 ? -3.23292  6.90759   11.07713  1.000 16.81106  ? 123 GLN A HA   1 
ATOM   2050 H HB2  . GLN A 1 131 ? -5.54674  7.24570   12.65527  1.000 17.28817  ? 123 GLN A HB2  1 
ATOM   2051 H HB3  . GLN A 1 131 ? -5.17689  8.24398   11.47541  1.000 17.28817  ? 123 GLN A HB3  1 
ATOM   2052 H HG2  . GLN A 1 131 ? -5.37948  6.47174   9.96217   1.000 26.90407  ? 123 GLN A HG2  1 
ATOM   2053 H HG3  . GLN A 1 131 ? -5.85001  5.53788   11.15880  1.000 26.90407  ? 123 GLN A HG3  1 
ATOM   2054 H HE21 . GLN A 1 131 ? -7.00492  8.56698   11.46421  1.000 54.94848  ? 123 GLN A HE21 1 
ATOM   2055 H HE22 . GLN A 1 131 ? -8.39652  8.38449   10.96526  1.000 54.94848  ? 123 GLN A HE22 1 
ATOM   2056 N N    . ALA A 1 132 ? -2.99360  8.06527   14.04486  1.000 11.43240  ? 124 ALA A N    1 
ATOM   2057 C CA   . ALA A 1 132 ? -2.28950  9.06873   14.83350  1.000 9.71542   ? 124 ALA A CA   1 
ATOM   2058 C C    . ALA A 1 132 ? -0.79306  9.01000   14.57836  1.000 12.68364  ? 124 ALA A C    1 
ATOM   2059 O O    . ALA A 1 132 ? -0.13496  10.05089  14.44243  1.000 12.52304  ? 124 ALA A O    1 
ATOM   2060 C CB   . ALA A 1 132 ? -2.57269  8.87203   16.32358  1.000 13.56906  ? 124 ALA A CB   1 
ATOM   2061 H H    . ALA A 1 132 ? -3.44776  7.49807   14.50489  1.000 13.73590  ? 124 ALA A H    1 
ATOM   2062 H HA   . ALA A 1 132 ? -2.61550  9.94561   14.57716  1.000 11.67553  ? 124 ALA A HA   1 
ATOM   2063 H HB1  . ALA A 1 132 ? -2.11185  9.56177   16.82636  1.000 16.29990  ? 124 ALA A HB1  1 
ATOM   2064 H HB2  . ALA A 1 132 ? -3.52877  8.93568   16.47442  1.000 16.29990  ? 124 ALA A HB2  1 
ATOM   2065 H HB3  . ALA A 1 132 ? -2.25287  7.99679   16.59297  1.000 16.29990  ? 124 ALA A HB3  1 
ATOM   2066 N N    . ALA A 1 133 ? -0.23079  7.79883   14.55036  1.000 10.04248  ? 125 ALA A N    1 
ATOM   2067 C CA   . ALA A 1 133 ? 1.20478   7.65837   14.34534  1.000 12.96511  ? 125 ALA A CA   1 
ATOM   2068 C C    . ALA A 1 133 ? 1.59453   8.02752   12.92270  1.000 11.62399  ? 125 ALA A C    1 
ATOM   2069 O O    . ALA A 1 133 ? 2.55817   8.77498   12.70789  1.000 16.25074  ? 125 ALA A O    1 
ATOM   2070 C CB   . ALA A 1 133 ? 1.64163   6.23231   14.67452  1.000 13.03019  ? 125 ALA A CB   1 
ATOM   2071 H H    . ALA A 1 133 ? -0.65426  7.05649   14.64629  1.000 12.06799  ? 125 ALA A H    1 
ATOM   2072 H HA   . ALA A 1 133 ? 1.66799   8.26119   14.94779  1.000 15.57515  ? 125 ALA A HA   1 
ATOM   2073 H HB1  . ALA A 1 133 ? 2.60569   6.16936   14.58774  1.000 15.65325  ? 125 ALA A HB1  1 
ATOM   2074 H HB2  . ALA A 1 133 ? 1.37701   6.02294   15.58394  1.000 15.65325  ? 125 ALA A HB2  1 
ATOM   2075 H HB3  . ALA A 1 133 ? 1.21316   5.62006   14.05609  1.000 15.65325  ? 125 ALA A HB3  1 
ATOM   2076 N N    . THR A 1 134 ? 0.87005   7.50069   11.93572  1.000 11.48882  ? 126 THR A N    1 
ATOM   2077 C CA   . THR A 1 134 ? 1.29555   7.66735   10.55097  1.000 15.84349  ? 126 THR A CA   1 
ATOM   2078 C C    . THR A 1 134 ? 0.99862   9.07095   10.03063  1.000 13.63341  ? 126 THR A C    1 
ATOM   2079 O O    . THR A 1 134 ? 1.80207   9.63735   9.28607   1.000 13.07824  ? 126 THR A O    1 
ATOM   2080 C CB   . THR A 1 134 ? 0.64381   6.60725   9.65118   1.000 12.30751  ? 126 THR A CB   1 
ATOM   2081 O OG1  . THR A 1 134 ? -0.78034  6.60037   9.80252   1.000 17.96554  ? 126 THR A OG1  1 
ATOM   2082 C CG2  . THR A 1 134 ? 1.18762   5.23472   9.97374   1.000 16.69488  ? 126 THR A CG2  1 
ATOM   2083 H H    . THR A 1 134 ? 0.14382   7.05209   12.04034  1.000 13.80361  ? 126 THR A H    1 
ATOM   2084 H HA   . THR A 1 134 ? 2.25531   7.53256   10.51107  1.000 19.02921  ? 126 THR A HA   1 
ATOM   2085 H HB   . THR A 1 134 ? 0.85039   6.82091   8.72783   1.000 14.78604  ? 126 THR A HB   1 
ATOM   2086 H HG1  . THR A 1 134 ? -0.99140  6.21337   10.51757  1.000 21.57567  ? 126 THR A HG1  1 
ATOM   2087 H HG21 . THR A 1 134 ? 0.74294   4.56555   9.43027   1.000 20.05088  ? 126 THR A HG21 1 
ATOM   2088 H HG22 . THR A 1 134 ? 2.14023   5.20450   9.79337   1.000 20.05088  ? 126 THR A HG22 1 
ATOM   2089 H HG23 . THR A 1 134 ? 1.03786   5.03016   10.91002  1.000 20.05088  ? 126 THR A HG23 1 
ATOM   2090 N N    . ASN A 1 135 ? -0.12642  9.66790   10.42612  1.000 15.57746  ? 127 ASN A N    1 
ATOM   2091 C CA   . ASN A 1 135 ? -0.38274  11.05165  10.03876  1.000 14.84477  ? 127 ASN A CA   1 
ATOM   2092 C C    . ASN A 1 135 ? 0.57216   12.01171  10.73155  1.000 15.80815  ? 127 ASN A C    1 
ATOM   2093 O O    . ASN A 1 135 ? 0.76920   13.13756  10.25113  1.000 16.14911  ? 127 ASN A O    1 
ATOM   2094 C CB   . ASN A 1 135 ? -1.83246  11.43338  10.35296  1.000 11.11516  ? 127 ASN A CB   1 
ATOM   2095 C CG   . ASN A 1 135 ? -2.81932  10.77053  9.42048   1.000 19.03746  ? 127 ASN A CG   1 
ATOM   2096 O OD1  . ASN A 1 135 ? -2.46036  10.32845  8.32418   1.000 23.51166  ? 127 ASN A OD1  1 
ATOM   2097 N ND2  . ASN A 1 135 ? -4.06230  10.66870  9.85943   1.000 21.17736  ? 127 ASN A ND2  1 
ATOM   2098 H H    . ASN A 1 135 ? -0.73969  9.30280   10.90592  1.000 18.70997  ? 127 ASN A H    1 
ATOM   2099 H HA   . ASN A 1 135 ? -0.26199  11.13938  9.08031   1.000 17.83074  ? 127 ASN A HA   1 
ATOM   2100 H HB2  . ASN A 1 135 ? -2.04342  11.15907  11.25913  1.000 13.35522  ? 127 ASN A HB2  1 
ATOM   2101 H HB3  . ASN A 1 135 ? -1.93367  12.39407  10.26509  1.000 13.35522  ? 127 ASN A HB3  1 
ATOM   2102 H HD21 . ASN A 1 135 ? -4.66322  10.29947  9.36732   1.000 25.42985  ? 127 ASN A HD21 1 
ATOM   2103 H HD22 . ASN A 1 135 ? -4.26990  10.97169  10.63705  1.000 25.42985  ? 127 ASN A HD22 1 
ATOM   2104 N N    . GLY A 1 136 ? 1.17009   11.58958  11.84519  1.000 12.74309  ? 128 GLY A N    1 
ATOM   2105 C CA   . GLY A 1 136 ? 2.25699   12.30668  12.46714  1.000 11.18384  ? 128 GLY A CA   1 
ATOM   2106 C C    . GLY A 1 136 ? 3.62427   11.86654  11.99848  1.000 15.95311  ? 128 GLY A C    1 
ATOM   2107 O O    . GLY A 1 136 ? 4.63021   12.31284  12.55889  1.000 15.61406  ? 128 GLY A O    1 
ATOM   2108 H H    . GLY A 1 136 ? 0.95075   10.87031  12.26250  1.000 15.30873  ? 128 GLY A H    1 
ATOM   2109 H HA2  . GLY A 1 136 ? 2.16253   13.25223  12.27244  1.000 13.43763  ? 128 GLY A HA2  1 
ATOM   2110 H HA3  . GLY A 1 136 ? 2.21188   12.17589  13.42722  1.000 13.43763  ? 128 GLY A HA3  1 
ATOM   2111 N N    . ASN A 1 137 ? 3.67381   11.01864  10.96758  1.000 15.24545  ? 129 ASN A N    1 
ATOM   2112 C CA   . ASN A 1 137 ? 4.91738   10.53285  10.36248  1.000 15.34741  ? 129 ASN A CA   1 
ATOM   2113 C C    . ASN A 1 137 ? 5.91394   10.02727  11.40795  1.000 13.18815  ? 129 ASN A C    1 
ATOM   2114 O O    . ASN A 1 137 ? 7.12458   10.30539  11.34689  1.000 16.09374  ? 129 ASN A O    1 
ATOM   2115 C CB   . ASN A 1 137 ? 5.52569   11.61221  9.47745   1.000 19.03267  ? 129 ASN A CB   1 
ATOM   2116 C CG   . ASN A 1 137 ? 4.67413   11.89072  8.24751   1.000 23.81630  ? 129 ASN A CG   1 
ATOM   2117 O OD1  . ASN A 1 137 ? 4.10383   12.96159  8.10450   1.000 30.41066  ? 129 ASN A OD1  1 
ATOM   2118 N ND2  . ASN A 1 137 ? 4.56549   10.90828  7.37067   1.000 28.33283  ? 129 ASN A ND2  1 
ATOM   2119 H H    . ASN A 1 137 ? 2.97327   10.69759  10.58579  1.000 18.31156  ? 129 ASN A H    1 
ATOM   2120 H HA   . ASN A 1 137 ? 4.70780   9.76498   9.80809   1.000 18.43391  ? 129 ASN A HA   1 
ATOM   2121 H HB2  . ASN A 1 137 ? 5.60226   12.43506  9.98535   1.000 22.85622  ? 129 ASN A HB2  1 
ATOM   2122 H HB3  . ASN A 1 137 ? 6.40247   11.32338  9.17959   1.000 22.85622  ? 129 ASN A HB3  1 
ATOM   2123 H HD21 . ASN A 1 137 ? 4.09492   11.01709  6.65910   1.000 34.01642  ? 129 ASN A HD21 1 
ATOM   2124 H HD22 . ASN A 1 137 ? 4.96535   10.16003  7.51152   1.000 34.01642  ? 129 ASN A HD22 1 
ATOM   2125 N N    A THR A 1 138 ? 5.40031   9.26535   12.36786  0.531 12.85628  ? 130 THR A N    1 
ATOM   2126 N N    B THR A 1 138 ? 5.40076   9.28055   12.38040  0.469 12.85184  ? 130 THR A N    1 
ATOM   2127 C CA   A THR A 1 138 ? 6.20512   8.54459   13.34123  0.531 11.45538  ? 130 THR A CA   1 
ATOM   2128 C CA   B THR A 1 138 ? 6.22419   8.54518   13.32718  0.469 11.46688  ? 130 THR A CA   1 
ATOM   2129 C C    A THR A 1 138 ? 6.07190   7.05045   13.08384  0.531 12.75457  ? 130 THR A C    1 
ATOM   2130 C C    B THR A 1 138 ? 6.08858   7.05575   13.05045  0.469 12.76411  ? 130 THR A C    1 
ATOM   2131 O O    A THR A 1 138 ? 5.02299   6.57556   12.64160  0.531 16.84804  ? 130 THR A O    1 
ATOM   2132 O O    B THR A 1 138 ? 5.05369   6.59001   12.56655  0.469 16.72334  ? 130 THR A O    1 
ATOM   2133 C CB   A THR A 1 138 ? 5.77022   8.88089   14.76904  0.531 16.65973  ? 130 THR A CB   1 
ATOM   2134 C CB   B THR A 1 138 ? 5.83040   8.83969   14.77698  0.469 16.61773  ? 130 THR A CB   1 
ATOM   2135 O OG1  A THR A 1 138 ? 5.77416   10.30375  14.92940  0.531 19.76713  ? 130 THR A OG1  1 
ATOM   2136 O OG1  B THR A 1 138 ? 4.47152   8.44465   14.99845  0.469 15.97419  ? 130 THR A OG1  1 
ATOM   2137 C CG2  A THR A 1 138 ? 6.71330   8.26176   15.78533  0.531 14.97571  ? 130 THR A CG2  1 
ATOM   2138 C CG2  B THR A 1 138 ? 6.01367   10.31576  15.07362  0.469 18.63909  ? 130 THR A CG2  1 
ATOM   2139 H H    A THR A 1 138 ? 4.55557   9.14733   12.47784  0.531 15.44456  ? 130 THR A H    1 
ATOM   2140 H H    B THR A 1 138 ? 4.55666   9.18342   12.51326  0.469 15.43923  ? 130 THR A H    1 
ATOM   2141 H HA   A THR A 1 138 ? 7.13961   8.79062   13.25696  0.531 13.76348  ? 130 THR A HA   1 
ATOM   2142 H HA   B THR A 1 138 ? 7.15209   8.80773   13.22243  0.469 13.77727  ? 130 THR A HA   1 
ATOM   2143 H HB   A THR A 1 138 ? 4.88192   8.52666   14.93135  0.531 20.00870  ? 130 THR A HB   1 
ATOM   2144 H HB   B THR A 1 138 ? 6.39596   8.34007   15.38643  0.469 19.95830  ? 130 THR A HB   1 
ATOM   2145 H HG1  A THR A 1 138 ? 5.65028   10.50229  15.73615  0.531 23.73758  ? 130 THR A HG1  1 
ATOM   2146 H HG1  B THR A 1 138 ? 4.20563   8.73380   15.74094  0.469 19.18605  ? 130 THR A HG1  1 
ATOM   2147 H HG21 A THR A 1 138 ? 6.44344   8.51081   16.68314  0.531 17.98788  ? 130 THR A HG21 1 
ATOM   2148 H HG21 B THR A 1 138 ? 5.68759   10.51810  15.96448  0.469 22.38393  ? 130 THR A HG21 1 
ATOM   2149 H HG22 A THR A 1 138 ? 6.69590   7.29499   15.70818  0.531 17.98788  ? 130 THR A HG22 1 
ATOM   2150 H HG22 B THR A 1 138 ? 6.95341   10.55044  15.02153  0.469 22.38393  ? 130 THR A HG22 1 
ATOM   2151 H HG23 A THR A 1 138 ? 7.61870   8.57365   15.63083  0.531 17.98788  ? 130 THR A HG23 1 
ATOM   2152 H HG23 B THR A 1 138 ? 5.52028   10.84735  14.42952  0.469 22.38393  ? 130 THR A HG23 1 
ATOM   2153 N N    . LEU A 1 139 ? 7.14475   6.30903   13.35847  1.000 12.16176  ? 131 LEU A N    1 
ATOM   2154 C CA   . LEU A 1 139 ? 7.14451   4.87335   13.10648  1.000 10.20262  ? 131 LEU A CA   1 
ATOM   2155 C C    . LEU A 1 139 ? 6.12350   4.15981   13.98516  1.000 10.31659  ? 131 LEU A C    1 
ATOM   2156 O O    . LEU A 1 139 ? 6.20358   4.20690   15.21652  1.000 10.94432  ? 131 LEU A O    1 
ATOM   2157 C CB   . LEU A 1 139 ? 8.53544   4.29523   13.34212  1.000 10.71773  ? 131 LEU A CB   1 
ATOM   2158 C CG   . LEU A 1 139 ? 8.76502   2.82952   12.97812  1.000 12.82704  ? 131 LEU A CG   1 
ATOM   2159 C CD1  . LEU A 1 139 ? 8.71515   2.62569   11.50221  1.000 15.08077  ? 131 LEU A CD1  1 
ATOM   2160 C CD2  . LEU A 1 139 ? 10.08850  2.32023   13.54114  1.000 14.75568  ? 131 LEU A CD2  1 
ATOM   2161 H H    . LEU A 1 139 ? 7.87801   6.61391   13.68857  1.000 14.61113  ? 131 LEU A H    1 
ATOM   2162 H HA   . LEU A 1 139 ? 6.89482   4.72783   12.18053  1.000 12.26017  ? 131 LEU A HA   1 
ATOM   2163 H HB2  . LEU A 1 139 ? 9.16474   4.81566   12.81864  1.000 12.87830  ? 131 LEU A HB2  1 
ATOM   2164 H HB3  . LEU A 1 139 ? 8.73658   4.38397   14.28688  1.000 12.87830  ? 131 LEU A HB3  1 
ATOM   2165 H HG   . LEU A 1 139 ? 8.05098   2.30746   13.37624  1.000 15.40948  ? 131 LEU A HG   1 
ATOM   2166 H HD11 . LEU A 1 139 ? 8.82788   1.68167   11.30980  1.000 18.11395  ? 131 LEU A HD11 1 
ATOM   2167 H HD12 . LEU A 1 139 ? 7.85632   2.93070   11.17013  1.000 18.11395  ? 131 LEU A HD12 1 
ATOM   2168 H HD13 . LEU A 1 139 ? 9.42956   3.13516   11.08873  1.000 18.11395  ? 131 LEU A HD13 1 
ATOM   2169 H HD21 . LEU A 1 139 ? 10.20370  1.39149   13.28603  1.000 17.72384  ? 131 LEU A HD21 1 
ATOM   2170 H HD22 . LEU A 1 139 ? 10.81233  2.85493   13.17913  1.000 17.72384  ? 131 LEU A HD22 1 
ATOM   2171 H HD23 . LEU A 1 139 ? 10.07125  2.39802   14.50786  1.000 17.72384  ? 131 LEU A HD23 1 
ATOM   2172 N N    . PHE A 1 140 ? 5.21035   3.43569   13.35140  1.000 9.59618   ? 132 PHE A N    1 
ATOM   2173 C CA   . PHE A 1 140 ? 4.17479   2.70266   14.06710  1.000 10.47887  ? 132 PHE A CA   1 
ATOM   2174 C C    . PHE A 1 140 ? 4.67301   1.30856   14.43531  1.000 11.88622  ? 132 PHE A C    1 
ATOM   2175 O O    . PHE A 1 140 ? 5.16403   0.57365   13.57324  1.000 11.31859  ? 132 PHE A O    1 
ATOM   2176 C CB   . PHE A 1 140 ? 2.91312   2.58744   13.21464  1.000 8.67351   ? 132 PHE A CB   1 
ATOM   2177 C CG   . PHE A 1 140 ? 1.74905   1.98017   13.93341  1.000 11.59401  ? 132 PHE A CG   1 
ATOM   2178 C CD1  . PHE A 1 140 ? 1.18027   2.62118   15.01566  1.000 14.15696  ? 132 PHE A CD1  1 
ATOM   2179 C CD2  . PHE A 1 140 ? 1.21497   0.77696   13.52088  1.000 13.34499  ? 132 PHE A CD2  1 
ATOM   2180 C CE1  . PHE A 1 140 ? 0.10880   2.05265   15.69182  1.000 13.52778  ? 132 PHE A CE1  1 
ATOM   2181 C CE2  . PHE A 1 140 ? 0.13684   0.22048   14.18889  1.000 13.78706  ? 132 PHE A CE2  1 
ATOM   2182 C CZ   . PHE A 1 140 ? -0.41166  0.85774   15.24822  1.000 11.70493  ? 132 PHE A CZ   1 
ATOM   2183 H H    . PHE A 1 140 ? 5.16879   3.35197   12.49649  1.000 11.53244  ? 132 PHE A H    1 
ATOM   2184 H HA   . PHE A 1 140 ? 3.95999   3.17878   14.88446  1.000 12.59167  ? 132 PHE A HA   1 
ATOM   2185 H HB2  . PHE A 1 140 ? 2.65098   3.47527   12.92492  1.000 10.42524  ? 132 PHE A HB2  1 
ATOM   2186 H HB3  . PHE A 1 140 ? 3.10763   2.03102   12.44427  1.000 10.42524  ? 132 PHE A HB3  1 
ATOM   2187 H HD1  . PHE A 1 140 ? 1.51789   3.44160   15.29462  1.000 17.00537  ? 132 PHE A HD1  1 
ATOM   2188 H HD2  . PHE A 1 140 ? 1.58165   0.33614   12.78867  1.000 16.03101  ? 132 PHE A HD2  1 
ATOM   2189 H HE1  . PHE A 1 140 ? -0.25363  2.47492   16.43696  1.000 16.25036  ? 132 PHE A HE1  1 
ATOM   2190 H HE2  . PHE A 1 140 ? -0.21138  -0.59478  13.90783  1.000 16.56150  ? 132 PHE A HE2  1 
ATOM   2191 H HZ   . PHE A 1 140 ? -1.14631  0.48580   15.68048  1.000 14.06293  ? 132 PHE A HZ   1 
ATOM   2192 N N    . ILE A 1 141 ? 4.53292   0.95781   15.71291  1.000 9.22120   ? 133 ILE A N    1 
ATOM   2193 C CA   . ILE A 1 141 ? 4.92347   -0.33022  16.28837  1.000 9.85106   ? 133 ILE A CA   1 
ATOM   2194 C C    . ILE A 1 141 ? 3.62791   -1.06394  16.63568  1.000 10.11127  ? 133 ILE A C    1 
ATOM   2195 O O    . ILE A 1 141 ? 2.96935   -0.75454  17.63988  1.000 13.45339  ? 133 ILE A O    1 
ATOM   2196 C CB   . ILE A 1 141 ? 5.81233   -0.13104  17.52217  1.000 8.75491   ? 133 ILE A CB   1 
ATOM   2197 C CG1  . ILE A 1 141 ? 7.03016   0.73338   17.16004  1.000 9.53778   ? 133 ILE A CG1  1 
ATOM   2198 C CG2  . ILE A 1 141 ? 6.21523   -1.45281  18.12420  1.000 10.02246  ? 133 ILE A CG2  1 
ATOM   2199 C CD1  . ILE A 1 141 ? 7.96692   0.09393   16.14179  1.000 12.91424  ? 133 ILE A CD1  1 
ATOM   2200 H H    . ILE A 1 141 ? 4.19259   1.48208   16.30360  1.000 11.08246  ? 133 ILE A H    1 
ATOM   2201 H HA   . ILE A 1 141 ? 5.40659   -0.85993  15.63499  1.000 11.83830  ? 133 ILE A HA   1 
ATOM   2202 H HB   . ILE A 1 141 ? 5.30158   0.34060   18.19863  1.000 10.52291  ? 133 ILE A HB   1 
ATOM   2203 H HG12 . ILE A 1 141 ? 6.71594   1.57125   16.78569  1.000 11.46236  ? 133 ILE A HG12 1 
ATOM   2204 H HG13 . ILE A 1 141 ? 7.54232   0.90166   17.96643  1.000 11.46236  ? 133 ILE A HG13 1 
ATOM   2205 H HG21 . ILE A 1 141 ? 6.77596   -1.28927  18.89863  1.000 12.04398  ? 133 ILE A HG21 1 
ATOM   2206 H HG22 . ILE A 1 141 ? 5.41678   -1.93529  18.38990  1.000 12.04398  ? 133 ILE A HG22 1 
ATOM   2207 H HG23 . ILE A 1 141 ? 6.70619   -1.96467  17.46249  1.000 12.04398  ? 133 ILE A HG23 1 
ATOM   2208 H HD11 . ILE A 1 141 ? 8.67496   0.72105   15.92662  1.000 15.51411  ? 133 ILE A HD11 1 
ATOM   2209 H HD12 . ILE A 1 141 ? 8.34502   -0.71347  16.52395  1.000 15.51411  ? 133 ILE A HD12 1 
ATOM   2210 H HD13 . ILE A 1 141 ? 7.46303   -0.12325  15.34189  1.000 15.51411  ? 133 ILE A HD13 1 
ATOM   2211 N N    . ASN A 1 142 ? 3.24576   -2.01908  15.78718  1.000 7.92121   ? 134 ASN A N    1 
ATOM   2212 C CA   . ASN A 1 142 ? 1.94622   -2.68305  15.84997  1.000 10.72899  ? 134 ASN A CA   1 
ATOM   2213 C C    . ASN A 1 142 ? 1.98555   -3.77550  16.90728  1.000 14.24608  ? 134 ASN A C    1 
ATOM   2214 O O    . ASN A 1 142 ? 2.58133   -4.83651  16.68964  1.000 10.79868  ? 134 ASN A O    1 
ATOM   2215 C CB   . ASN A 1 142 ? 1.60864   -3.26241  14.48143  1.000 11.05751  ? 134 ASN A CB   1 
ATOM   2216 C CG   . ASN A 1 142 ? 0.15400   -3.67316  14.35335  1.000 11.97782  ? 134 ASN A CG   1 
ATOM   2217 O OD1  . ASN A 1 142 ? -0.67479  -3.39731  15.22866  1.000 14.93381  ? 134 ASN A OD1  1 
ATOM   2218 N ND2  . ASN A 1 142 ? -0.17958  -4.28587  13.21524  1.000 15.26787  ? 134 ASN A ND2  1 
ATOM   2219 H H    . ASN A 1 142 ? 3.73882   -2.30913  15.14503  1.000 9.52247   ? 134 ASN A H    1 
ATOM   2220 H HA   . ASN A 1 142 ? 1.26373   -2.04312  16.10607  1.000 12.89182  ? 134 ASN A HA   1 
ATOM   2221 H HB2  . ASN A 1 142 ? 1.79126   -2.59404  13.80259  1.000 13.28604  ? 134 ASN A HB2  1 
ATOM   2222 H HB3  . ASN A 1 142 ? 2.15571   -4.04869  14.32850  1.000 13.28604  ? 134 ASN A HB3  1 
ATOM   2223 H HD21 . ASN A 1 142 ? -0.99044  -4.54174  13.08630  1.000 18.33846  ? 134 ASN A HD21 1 
ATOM   2224 H HD22 . ASN A 1 142 ? 0.41638   -4.42472  12.61097  1.000 18.33846  ? 134 ASN A HD22 1 
ATOM   2225 N N    . ALA A 1 143 ? 1.34570   -3.51310  18.04354  1.000 9.33793   ? 135 ALA A N    1 
ATOM   2226 C CA   . ALA A 1 143 ? 1.32825   -4.42709  19.17739  1.000 8.97909   ? 135 ALA A CA   1 
ATOM   2227 C C    . ALA A 1 143 ? 0.14952   -5.37141  19.03435  1.000 9.86962   ? 135 ALA A C    1 
ATOM   2228 O O    . ALA A 1 143 ? -1.00157  -4.93292  19.05385  1.000 10.57924  ? 135 ALA A O    1 
ATOM   2229 C CB   . ALA A 1 143 ? 1.21216   -3.66775  20.49462  1.000 10.92762  ? 135 ALA A CB   1 
ATOM   2230 H H    . ALA A 1 143 ? 0.90166   -2.79024  18.18461  1.000 11.22254  ? 135 ALA A H    1 
ATOM   2231 H HA   . ALA A 1 143 ? 2.15454   -4.93515  19.18234  1.000 10.79193  ? 135 ALA A HA   1 
ATOM   2232 H HB1  . ALA A 1 143 ? 1.18214   -4.30529  21.22507  1.000 13.13016  ? 135 ALA A HB1  1 
ATOM   2233 H HB2  . ALA A 1 143 ? 1.98306   -3.08740  20.59358  1.000 13.13016  ? 135 ALA A HB2  1 
ATOM   2234 H HB3  . ALA A 1 143 ? 0.39915   -3.13880  20.48362  1.000 13.13016  ? 135 ALA A HB3  1 
ATOM   2235 N N    . THR A 1 144 ? 0.43448   -6.66557  18.94603  1.000 10.30319  ? 136 THR A N    1 
ATOM   2236 C CA   . THR A 1 144 ? -0.59193  -7.65107  18.61981  1.000 9.22921   ? 136 THR A CA   1 
ATOM   2237 C C    . THR A 1 144 ? -0.78591  -8.69045  19.72082  1.000 11.25597  ? 136 THR A C    1 
ATOM   2238 O O    . THR A 1 144 ? -1.31902  -9.77911  19.46244  1.000 12.70706  ? 136 THR A O    1 
ATOM   2239 C CB   . THR A 1 144 ? -0.25488  -8.32483  17.28544  1.000 9.97937   ? 136 THR A CB   1 
ATOM   2240 O OG1  . THR A 1 144 ? 1.04557   -8.92340  17.34732  1.000 13.41308  ? 136 THR A OG1  1 
ATOM   2241 C CG2  . THR A 1 144 ? -0.28983  -7.31018  16.14897  1.000 13.49889  ? 136 THR A CG2  1 
ATOM   2242 H H    . THR A 1 144 ? 1.21718   -6.99928  19.07096  1.000 12.38085  ? 136 THR A H    1 
ATOM   2243 H HA   . THR A 1 144 ? -1.44192  -7.19342  18.52509  1.000 11.09208  ? 136 THR A HA   1 
ATOM   2244 H HB   . THR A 1 144 ? -0.91266  -9.01436  17.10440  1.000 11.99226  ? 136 THR A HB   1 
ATOM   2245 H HG1  . THR A 1 144 ? 1.19233   -9.36464  16.64777  1.000 16.11271  ? 136 THR A HG1  1 
ATOM   2246 H HG21 . THR A 1 144 ? -0.11400  -7.75250  15.30379  1.000 16.21569  ? 136 THR A HG21 1 
ATOM   2247 H HG22 . THR A 1 144 ? -1.16218  -6.88803  16.10784  1.000 16.21569  ? 136 THR A HG22 1 
ATOM   2248 H HG23 . THR A 1 144 ? 0.38386   -6.62732  16.29305  1.000 16.21569  ? 136 THR A HG23 1 
ATOM   2249 N N    . TRP A 1 145 ? -0.44066  -8.36056  20.96040  1.000 8.78491   ? 137 TRP A N    1 
ATOM   2250 C CA   . TRP A 1 145 ? -0.58537  -9.34131  22.02010  1.000 12.04462  ? 137 TRP A CA   1 
ATOM   2251 C C    . TRP A 1 145 ? -2.01894  -9.49759  22.51231  1.000 11.64821  ? 137 TRP A C    1 
ATOM   2252 O O    . TRP A 1 145 ? -2.33659  -10.52004 23.13024  1.000 13.15725  ? 137 TRP A O    1 
ATOM   2253 C CB   . TRP A 1 145 ? 0.31244   -8.99077  23.19162  1.000 11.74467  ? 137 TRP A CB   1 
ATOM   2254 C CG   . TRP A 1 145 ? 0.31116   -7.57036  23.70889  1.000 10.21220  ? 137 TRP A CG   1 
ATOM   2255 C CD1  . TRP A 1 145 ? -0.61800  -6.99014  24.51708  1.000 9.13050   ? 137 TRP A CD1  1 
ATOM   2256 C CD2  . TRP A 1 145 ? 1.32130   -6.57827  23.48870  1.000 9.79539   ? 137 TRP A CD2  1 
ATOM   2257 N NE1  . TRP A 1 145 ? -0.24371  -5.70328  24.82651  1.000 10.15627  ? 137 TRP A NE1  1 
ATOM   2258 C CE2  . TRP A 1 145 ? 0.94466   -5.43068  24.21026  1.000 10.53214  ? 137 TRP A CE2  1 
ATOM   2259 C CE3  . TRP A 1 145 ? 2.50830   -6.55264  22.75817  1.000 11.07118  ? 137 TRP A CE3  1 
ATOM   2260 C CZ2  . TRP A 1 145 ? 1.69905   -4.27176  24.20823  1.000 10.47005  ? 137 TRP A CZ2  1 
ATOM   2261 C CZ3  . TRP A 1 145 ? 3.27010   -5.39948  22.77392  1.000 12.85502  ? 137 TRP A CZ3  1 
ATOM   2262 C CH2  . TRP A 1 145 ? 2.86706   -4.27975  23.50178  1.000 11.59193  ? 137 TRP A CH2  1 
ATOM   2263 H H    . TRP A 1 145 ? -0.12936  -7.59669  21.20372  1.000 10.55892  ? 137 TRP A H    1 
ATOM   2264 H HA   . TRP A 1 145 ? -0.30256  -10.19990 21.66833  1.000 14.47057  ? 137 TRP A HA   1 
ATOM   2265 H HB2  . TRP A 1 145 ? 0.05367   -9.55456  23.93732  1.000 14.11062  ? 137 TRP A HB2  1 
ATOM   2266 H HB3  . TRP A 1 145 ? 1.22552   -9.18633  22.92907  1.000 14.11062  ? 137 TRP A HB3  1 
ATOM   2267 H HD1  . TRP A 1 145 ? -1.39466  -7.40453  24.81705  1.000 10.97362  ? 137 TRP A HD1  1 
ATOM   2268 H HE1  . TRP A 1 145 ? -0.68514  -5.15972  25.32578  1.000 12.20455  ? 137 TRP A HE1  1 
ATOM   2269 H HE3  . TRP A 1 145 ? 2.78183   -7.29578  22.27049  1.000 13.30244  ? 137 TRP A HE3  1 
ATOM   2270 H HZ2  . TRP A 1 145 ? 1.42085   -3.51468  24.67119  1.000 12.58109  ? 137 TRP A HZ2  1 
ATOM   2271 H HZ3  . TRP A 1 145 ? 4.06451   -5.36956  22.29130  1.000 15.44304  ? 137 TRP A HZ3  1 
ATOM   2272 H HH2  . TRP A 1 145 ? 3.40607   -3.52189  23.50581  1.000 13.92734  ? 137 TRP A HH2  1 
ATOM   2273 N N    . TYR A 1 146 ? -2.88339  -8.51619  22.27490  1.000 11.49530  ? 138 TYR A N    1 
ATOM   2274 C CA   . TYR A 1 146 ? -4.29268  -8.62135  22.64641  1.000 11.89423  ? 138 TYR A CA   1 
ATOM   2275 C C    . TYR A 1 146 ? -5.21270  -8.86456  21.45599  1.000 17.70120  ? 138 TYR A C    1 
ATOM   2276 O O    . TYR A 1 146 ? -6.18575  -9.62498  21.56644  1.000 14.51825  ? 138 TYR A O    1 
ATOM   2277 C CB   . TYR A 1 146 ? -4.73742  -7.35292  23.38930  1.000 14.68847  ? 138 TYR A CB   1 
ATOM   2278 C CG   . TYR A 1 146 ? -4.34732  -7.31422  24.85801  1.000 9.67420   ? 138 TYR A CG   1 
ATOM   2279 C CD1  . TYR A 1 146 ? -4.47160  -8.43904  25.66277  1.000 12.44919  ? 138 TYR A CD1  1 
ATOM   2280 C CD2  . TYR A 1 146 ? -3.84090  -6.16449  25.42713  1.000 13.41848  ? 138 TYR A CD2  1 
ATOM   2281 C CE1  . TYR A 1 146 ? -4.13711  -8.40515  26.98706  1.000 13.61361  ? 138 TYR A CE1  1 
ATOM   2282 C CE2  . TYR A 1 146 ? -3.48933  -6.12126  26.75149  1.000 10.56418  ? 138 TYR A CE2  1 
ATOM   2283 C CZ   . TYR A 1 146 ? -3.63146  -7.24486  27.53103  1.000 13.69213  ? 138 TYR A CZ   1 
ATOM   2284 O OH   . TYR A 1 146 ? -3.29368  -7.21479  28.86800  1.000 14.39695  ? 138 TYR A OH   1 
ATOM   2285 H H    . TYR A 1 146 ? -2.67627  -7.77233  21.89625  1.000 13.81138  ? 138 TYR A H    1 
ATOM   2286 H HA   . TYR A 1 146 ? -4.40210  -9.36876  23.25494  1.000 14.29010  ? 138 TYR A HA   1 
ATOM   2287 H HB2  . TYR A 1 146 ? -4.33245  -6.58415  22.95815  1.000 17.64319  ? 138 TYR A HB2  1 
ATOM   2288 H HB3  . TYR A 1 146 ? -5.70413  -7.28934  23.34106  1.000 17.64319  ? 138 TYR A HB3  1 
ATOM   2289 H HD1  . TYR A 1 146 ? -4.78882  -9.23120  25.29297  1.000 14.95605  ? 138 TYR A HD1  1 
ATOM   2290 H HD2  . TYR A 1 146 ? -3.73590  -5.40391  24.90236  1.000 16.11920  ? 138 TYR A HD2  1 
ATOM   2291 H HE1  . TYR A 1 146 ? -4.25005  -9.16045  27.51779  1.000 16.35335  ? 138 TYR A HE1  1 
ATOM   2292 H HE2  . TYR A 1 146 ? -3.15621  -5.33549  27.12095  1.000 12.69403  ? 138 TYR A HE2  1 
ATOM   2293 H HH   . TYR A 1 146 ? -3.01178  -6.45133  29.07600  1.000 17.29337  ? 138 TYR A HH   1 
ATOM   2294 N N    . GLU A 1 147 ? -4.92989  -8.26582  20.30283  1.000 14.44334  ? 139 GLU A N    1 
ATOM   2295 C CA   . GLU A 1 147 ? -5.75555  -8.45557  19.11397  1.000 13.15282  ? 139 GLU A CA   1 
ATOM   2296 C C    . GLU A 1 147 ? -4.83594  -8.81231  17.94894  1.000 14.00035  ? 139 GLU A C    1 
ATOM   2297 O O    . GLU A 1 147 ? -3.97403  -7.99286  17.56956  1.000 12.46226  ? 139 GLU A O    1 
ATOM   2298 C CB   . GLU A 1 147 ? -6.58501  -7.21193  18.79813  1.000 14.00682  ? 139 GLU A CB   1 
ATOM   2299 C CG   . GLU A 1 147 ? -7.69419  -6.95518  19.78508  1.000 15.90922  ? 139 GLU A CG   1 
ATOM   2300 C CD   . GLU A 1 147 ? -8.74487  -8.05366  19.78958  1.000 28.09736  ? 139 GLU A CD   1 
ATOM   2301 O OE1  . GLU A 1 147 ? -8.90058  -8.75264  18.76380  1.000 22.01886  ? 139 GLU A OE1  1 
ATOM   2302 O OE2  . GLU A 1 147 ? -9.42027  -8.21526  20.82078  1.000 21.92381  ? 139 GLU A OE2  1 
ATOM   2303 H H    . GLU A 1 147 ? -4.25950  -7.74062  20.18313  1.000 17.34903  ? 139 GLU A H    1 
ATOM   2304 H HA   . GLU A 1 147 ? -6.36838  -9.19177  19.26681  1.000 15.80040  ? 139 GLU A HA   1 
ATOM   2305 H HB2  . GLU A 1 147 ? -6.00030  -6.43798  18.80184  1.000 16.82520  ? 139 GLU A HB2  1 
ATOM   2306 H HB3  . GLU A 1 147 ? -6.98722  -7.31965  17.92205  1.000 16.82520  ? 139 GLU A HB3  1 
ATOM   2307 H HG2  . GLU A 1 147 ? -7.31665  -6.89789  20.67675  1.000 19.10808  ? 139 GLU A HG2  1 
ATOM   2308 H HG3  . GLU A 1 147 ? -8.13355  -6.12112  19.55661  1.000 19.10808  ? 139 GLU A HG3  1 
ATOM   2309 N N    . PRO A 1 148 ? -4.96815  -9.99906  17.36984  1.000 14.36252  ? 140 PRO A N    1 
ATOM   2310 C CA   . PRO A 1 148 ? -4.04114  -10.39410 16.30486  1.000 13.16869  ? 140 PRO A CA   1 
ATOM   2311 C C    . PRO A 1 148 ? -4.27459  -9.60302  15.02778  1.000 10.92348  ? 140 PRO A C    1 
ATOM   2312 O O    . PRO A 1 148 ? -5.33230  -9.00027  14.80527  1.000 13.78811  ? 140 PRO A O    1 
ATOM   2313 C CB   . PRO A 1 148 ? -4.34986  -11.88493 16.09528  1.000 20.45316  ? 140 PRO A CB   1 
ATOM   2314 C CG   . PRO A 1 148 ? -5.79870  -12.00656 16.46443  1.000 23.48838  ? 140 PRO A CG   1 
ATOM   2315 C CD   . PRO A 1 148 ? -5.99616  -11.02876 17.62320  1.000 24.20253  ? 140 PRO A CD   1 
ATOM   2316 H HA   . PRO A 1 148 ? -3.12160  -10.28364 16.59324  1.000 15.81945  ? 140 PRO A HA   1 
ATOM   2317 H HB2  . PRO A 1 148 ? -4.20154  -12.13056 15.16869  1.000 24.56082  ? 140 PRO A HB2  1 
ATOM   2318 H HB3  . PRO A 1 148 ? -3.79273  -12.42704 16.67547  1.000 24.56082  ? 140 PRO A HB3  1 
ATOM   2319 H HG2  . PRO A 1 148 ? -6.35419  -11.76341 15.70733  1.000 28.20308  ? 140 PRO A HG2  1 
ATOM   2320 H HG3  . PRO A 1 148 ? -5.99411  -12.91556 16.74092  1.000 28.20308  ? 140 PRO A HG3  1 
ATOM   2321 H HD2  . PRO A 1 148 ? -6.88563  -10.64235 17.60227  1.000 29.06006  ? 140 PRO A HD2  1 
ATOM   2322 H HD3  . PRO A 1 148 ? -5.84469  -11.46676 18.47532  1.000 29.06006  ? 140 PRO A HD3  1 
ATOM   2323 N N    . VAL A 1 149 ? -3.24434  -9.61242  14.18112  1.000 13.17653  ? 141 VAL A N    1 
ATOM   2324 C CA   . VAL A 1 149 ? -3.29548  -9.02134  12.85134  1.000 12.95918  ? 141 VAL A CA   1 
ATOM   2325 C C    . VAL A 1 149 ? -2.82835  -10.07189 11.84854  1.000 14.90249  ? 141 VAL A C    1 
ATOM   2326 O O    . VAL A 1 149 ? -1.75719  -10.66605 12.01209  1.000 19.07576  ? 141 VAL A O    1 
ATOM   2327 C CB   . VAL A 1 149 ? -2.43273  -7.74728  12.75841  1.000 14.59293  ? 141 VAL A CB   1 
ATOM   2328 C CG1  . VAL A 1 149 ? -2.25849  -7.31355  11.29848  1.000 15.63363  ? 141 VAL A CG1  1 
ATOM   2329 C CG2  . VAL A 1 149 ? -3.02283  -6.62862  13.59927  1.000 16.27526  ? 141 VAL A CG2  1 
ATOM   2330 H H    . VAL A 1 149 ? -2.48274  -9.96756  14.36395  1.000 15.82886  ? 141 VAL A H    1 
ATOM   2331 H HA   . VAL A 1 149 ? -4.20995  -8.78023  12.63565  1.000 15.56804  ? 141 VAL A HA   1 
ATOM   2332 H HB   . VAL A 1 149 ? -1.55182  -7.94413  13.11359  1.000 17.52854  ? 141 VAL A HB   1 
ATOM   2333 H HG11 . VAL A 1 149 ? -1.91469  -6.40676  11.27732  1.000 18.77738  ? 141 VAL A HG11 1 
ATOM   2334 H HG12 . VAL A 1 149 ? -1.63383  -7.91438  10.86294  1.000 18.77738  ? 141 VAL A HG12 1 
ATOM   2335 H HG13 . VAL A 1 149 ? -3.11926  -7.35144  10.85290  1.000 18.77738  ? 141 VAL A HG13 1 
ATOM   2336 H HG21 . VAL A 1 149 ? -2.46730  -5.83864  13.50856  1.000 19.54734  ? 141 VAL A HG21 1 
ATOM   2337 H HG22 . VAL A 1 149 ? -3.92127  -6.43886  13.28671  1.000 19.54734  ? 141 VAL A HG22 1 
ATOM   2338 H HG23 . VAL A 1 149 ? -3.04801  -6.91054  14.52705  1.000 19.54734  ? 141 VAL A HG23 1 
ATOM   2339 N N    . THR A 1 150 ? -3.64546  -10.32573 10.82788  1.000 18.09937  ? 142 THR A N    1 
ATOM   2340 C CA   . THR A 1 150 ? -3.29529  -11.30697 9.80874   1.000 21.22056  ? 142 THR A CA   1 
ATOM   2341 C C    . THR A 1 150 ? -2.94233  -10.68926 8.46282   1.000 20.48337  ? 142 THR A C    1 
ATOM   2342 O O    . THR A 1 150 ? -2.34324  -11.37170 7.62744   1.000 24.34658  ? 142 THR A O    1 
ATOM   2343 C CB   . THR A 1 150 ? -4.45465  -12.29897 9.59655   1.000 22.24408  ? 142 THR A CB   1 
ATOM   2344 O OG1  . THR A 1 150 ? -5.60759  -11.58455 9.13742   1.000 24.48297  ? 142 THR A OG1  1 
ATOM   2345 C CG2  . THR A 1 150 ? -4.78580  -13.02757 10.89422  1.000 26.33034  ? 142 THR A CG2  1 
ATOM   2346 H H    . THR A 1 150 ? -4.40567  -9.94263  10.70578  1.000 21.73626  ? 142 THR A H    1 
ATOM   2347 H HA   . THR A 1 150 ? -2.52561  -11.80877 10.11969  1.000 25.48170  ? 142 THR A HA   1 
ATOM   2348 H HB   . THR A 1 150 ? -4.20018  -12.96376 8.93762   1.000 26.70991  ? 142 THR A HB   1 
ATOM   2349 H HG1  . THR A 1 150 ? -6.24961  -12.11507 9.02809   1.000 29.39659  ? 142 THR A HG1  1 
ATOM   2350 H HG21 . THR A 1 150 ? -5.48131  -13.68523 10.73725  1.000 31.61343  ? 142 THR A HG21 1 
ATOM   2351 H HG22 . THR A 1 150 ? -3.99639  -13.47875 11.23212  1.000 31.61343  ? 142 THR A HG22 1 
ATOM   2352 H HG23 . THR A 1 150 ? -5.09586  -12.39435 11.56040  1.000 31.61343  ? 142 THR A HG23 1 
ATOM   2353 N N    . GLU A 1 151 ? -3.29460  -9.42590  8.23338   1.000 16.61664  ? 143 GLU A N    1 
ATOM   2354 C CA   . GLU A 1 151 ? -3.15285  -8.84156  6.90502   1.000 17.92332  ? 143 GLU A CA   1 
ATOM   2355 C C    . GLU A 1 151 ? -1.70150  -8.53767  6.55751   1.000 27.32753  ? 143 GLU A C    1 
ATOM   2356 O O    . GLU A 1 151 ? -1.33100  -8.59798  5.38076   1.000 21.66201  ? 143 GLU A O    1 
ATOM   2357 C CB   . GLU A 1 151 ? -3.98849  -7.57002  6.81125   1.000 22.98328  ? 143 GLU A CB   1 
ATOM   2358 C CG   . GLU A 1 151 ? -3.96698  -6.89501  5.44996   1.000 45.97504  ? 143 GLU A CG   1 
ATOM   2359 C CD   . GLU A 1 151 ? -4.87768  -5.67645  5.39010   1.000 70.23711  ? 143 GLU A CD   1 
ATOM   2360 O OE1  . GLU A 1 151 ? -5.89251  -5.65366  6.12373   1.000 49.62230  ? 143 GLU A OE1  1 
ATOM   2361 O OE2  . GLU A 1 151 ? -4.57610  -4.74323  4.61122   1.000 51.44719  ? 143 GLU A OE2  1 
ATOM   2362 H H    . GLU A 1 151 ? -3.61558  -8.89050  8.82492   1.000 19.95699  ? 143 GLU A H    1 
ATOM   2363 H HA   . GLU A 1 151 ? -3.48221  -9.48009  6.25333   1.000 21.52501  ? 143 GLU A HA   1 
ATOM   2364 H HB2  . GLU A 1 151 ? -4.91101  -7.79202  7.01269   1.000 27.59695  ? 143 GLU A HB2  1 
ATOM   2365 H HB3  . GLU A 1 151 ? -3.65180  -6.93156  7.45925   1.000 27.59695  ? 143 GLU A HB3  1 
ATOM   2366 H HG2  . GLU A 1 151 ? -3.06237  -6.60480  5.25409   1.000 55.18707  ? 143 GLU A HG2  1 
ATOM   2367 H HG3  . GLU A 1 151 ? -4.26543  -7.52732  4.77764   1.000 55.18707  ? 143 GLU A HG3  1 
ATOM   2368 N N    . TYR A 1 152 ? -0.87158  -8.19819  7.54136   1.000 16.89506  ? 144 TYR A N    1 
ATOM   2369 C CA   . TYR A 1 152 ? 0.52040   -7.86883  7.24969   1.000 18.31838  ? 144 TYR A CA   1 
ATOM   2370 C C    . TYR A 1 152 ? 1.37013   -8.09086  8.49488   1.000 19.79688  ? 144 TYR A C    1 
ATOM   2371 O O    . TYR A 1 152 ? 0.85833   -8.32024  9.59087   1.000 17.10088  ? 144 TYR A O    1 
ATOM   2372 C CB   . TYR A 1 152 ? 0.65187   -6.43011  6.72968   1.000 20.59879  ? 144 TYR A CB   1 
ATOM   2373 C CG   . TYR A 1 152 ? -0.17677  -5.40931  7.48366   1.000 20.93235  ? 144 TYR A CG   1 
ATOM   2374 C CD1  . TYR A 1 152 ? 0.21176   -4.95997  8.73885   1.000 16.10087  ? 144 TYR A CD1  1 
ATOM   2375 C CD2  . TYR A 1 152 ? -1.33482  -4.88037  6.93014   1.000 20.01340  ? 144 TYR A CD2  1 
ATOM   2376 C CE1  . TYR A 1 152 ? -0.53272  -4.01538  9.42036   1.000 17.46913  ? 144 TYR A CE1  1 
ATOM   2377 C CE2  . TYR A 1 152 ? -2.09807  -3.94988  7.60879   1.000 19.00769  ? 144 TYR A CE2  1 
ATOM   2378 C CZ   . TYR A 1 152 ? -1.69488  -3.51865  8.85593   1.000 20.59777  ? 144 TYR A CZ   1 
ATOM   2379 O OH   . TYR A 1 152 ? -2.44015  -2.57634  9.53633   1.000 25.14811  ? 144 TYR A OH   1 
ATOM   2380 H H    . TYR A 1 152 ? -1.08751  -8.15214  8.37253   1.000 20.29109  ? 144 TYR A H    1 
ATOM   2381 H HA   . TYR A 1 152 ? 0.84839   -8.47524  6.56734   1.000 21.99908  ? 144 TYR A HA   1 
ATOM   2382 H HB2  . TYR A 1 152 ? 1.58121   -6.16080  6.79822   1.000 24.73557  ? 144 TYR A HB2  1 
ATOM   2383 H HB3  . TYR A 1 152 ? 0.36814   -6.40992  5.80232   1.000 24.73557  ? 144 TYR A HB3  1 
ATOM   2384 H HD1  . TYR A 1 152 ? 0.98533   -5.30001  9.12725   1.000 19.33806  ? 144 TYR A HD1  1 
ATOM   2385 H HD2  . TYR A 1 152 ? -1.60270  -5.15843  6.08407   1.000 24.03310  ? 144 TYR A HD2  1 
ATOM   2386 H HE1  . TYR A 1 152 ? -0.25376  -3.71474  10.25504  1.000 20.97998  ? 144 TYR A HE1  1 
ATOM   2387 H HE2  . TYR A 1 152 ? -2.87815  -3.61653  7.22767   1.000 22.82626  ? 144 TYR A HE2  1 
ATOM   2388 H HH   . TYR A 1 152 ? -3.11691  -2.93766  9.87845   1.000 30.19475  ? 144 TYR A HH   1 
ATOM   2389 N N    . GLY A 1 153 ? 2.68205   -8.04090  8.30283   1.000 14.05187  ? 145 GLY A N    1 
ATOM   2390 C CA   . GLY A 1 153 ? 3.66122   -8.31379  9.34714   1.000 15.13768  ? 145 GLY A CA   1 
ATOM   2391 C C    . GLY A 1 153 ? 4.24167   -7.04746  9.94435   1.000 12.32181  ? 145 GLY A C    1 
ATOM   2392 O O    . GLY A 1 153 ? 3.54893   -6.03192  10.08497  1.000 12.53226  ? 145 GLY A O    1 
ATOM   2393 H H    . GLY A 1 153 ? 3.04272   -7.84368  7.54744   1.000 16.87926  ? 145 GLY A H    1 
ATOM   2394 H HA2  . GLY A 1 153 ? 3.23874   -8.82048  10.05825  1.000 18.18224  ? 145 GLY A HA2  1 
ATOM   2395 H HA3  . GLY A 1 153 ? 4.38866   -8.83704  8.97573   1.000 18.18224  ? 145 GLY A HA3  1 
ATOM   2396 N N    . PHE A 1 154 ? 5.54134   -7.09914  10.27538  1.000 10.89905  ? 146 PHE A N    1 
ATOM   2397 C CA   . PHE A 1 154 ? 6.20922   -6.03596  11.04319  1.000 12.10300  ? 146 PHE A CA   1 
ATOM   2398 C C    . PHE A 1 154 ? 5.44458   -5.77694  12.33798  1.000 11.07036  ? 146 PHE A C    1 
ATOM   2399 O O    . PHE A 1 154 ? 5.26479   -4.62899  12.76745  1.000 14.49798  ? 146 PHE A O    1 
ATOM   2400 C CB   . PHE A 1 154 ? 6.37233   -4.75563  10.20904  1.000 11.50132  ? 146 PHE A CB   1 
ATOM   2401 C CG   . PHE A 1 154 ? 7.26044   -3.70886  10.84580  1.000 12.58974  ? 146 PHE A CG   1 
ATOM   2402 C CD1  . PHE A 1 154 ? 8.48540   -4.04085  11.38382  1.000 15.54785  ? 146 PHE A CD1  1 
ATOM   2403 C CD2  . PHE A 1 154 ? 6.86450   -2.38899  10.90003  1.000 12.73830  ? 146 PHE A CD2  1 
ATOM   2404 C CE1  . PHE A 1 154 ? 9.29958   -3.07297  11.96360  1.000 15.17168  ? 146 PHE A CE1  1 
ATOM   2405 C CE2  . PHE A 1 154 ? 7.67308   -1.41357  11.48260  1.000 15.17146  ? 146 PHE A CE2  1 
ATOM   2406 C CZ   . PHE A 1 154 ? 8.88243   -1.75636  12.01590  1.000 17.95883  ? 146 PHE A CZ   1 
ATOM   2407 H H    . PHE A 1 154 ? 6.06428   -7.74830  10.06391  1.000 13.09589  ? 146 PHE A H    1 
ATOM   2408 H HA   . PHE A 1 154 ? 7.10472   -6.32603  11.27741  1.000 14.54062  ? 146 PHE A HA   1 
ATOM   2409 H HB2  . PHE A 1 154 ? 6.76258   -4.99100  9.35277   1.000 13.81861  ? 146 PHE A HB2  1 
ATOM   2410 H HB3  . PHE A 1 154 ? 5.49746   -4.35809  10.07685  1.000 13.81861  ? 146 PHE A HB3  1 
ATOM   2411 H HD1  . PHE A 1 154 ? 8.77197   -4.92525  11.35888  1.000 18.67444  ? 146 PHE A HD1  1 
ATOM   2412 H HD2  . PHE A 1 154 ? 6.04211   -2.14463  10.54105  1.000 15.30299  ? 146 PHE A HD2  1 
ATOM   2413 H HE1  . PHE A 1 154 ? 10.12601  -3.31239  12.31659  1.000 18.22304  ? 146 PHE A HE1  1 
ATOM   2414 H HE2  . PHE A 1 154 ? 7.38832   -0.52860  11.50792  1.000 18.22278  ? 146 PHE A HE2  1 
ATOM   2415 H HZ   . PHE A 1 154 ? 9.42096   -1.10926  12.41106  1.000 21.56762  ? 146 PHE A HZ   1 
ATOM   2416 N N    . GLN A 1 155 ? 4.99843   -6.87244  12.96520  1.000 11.73369  ? 147 GLN A N    1 
ATOM   2417 C CA   . GLN A 1 155 ? 4.22914   -6.82453  14.19713  1.000 11.18975  ? 147 GLN A CA   1 
ATOM   2418 C C    . GLN A 1 155 ? 5.14095   -7.10424  15.38199  1.000 11.59877  ? 147 GLN A C    1 
ATOM   2419 O O    . GLN A 1 155 ? 6.26168   -7.60366  15.24197  1.000 11.64962  ? 147 GLN A O    1 
ATOM   2420 C CB   . GLN A 1 155 ? 3.09388   -7.85690  14.23596  1.000 19.29929  ? 147 GLN A CB   1 
ATOM   2421 C CG   . GLN A 1 155 ? 2.24083   -7.99223  13.03461  1.000 28.38646  ? 147 GLN A CG   1 
ATOM   2422 C CD   . GLN A 1 155 ? 1.29844   -9.16382  13.19639  1.000 14.15154  ? 147 GLN A CD   1 
ATOM   2423 O OE1  . GLN A 1 155 ? 1.17126   -9.75198  14.30429  1.000 15.64924  ? 147 GLN A OE1  1 
ATOM   2424 N NE2  . GLN A 1 155 ? 0.64492   -9.52638  12.11470  1.000 17.48706  ? 147 GLN A NE2  1 
ATOM   2425 H H    . GLN A 1 155 ? 5.13662   -7.67277  12.68242  1.000 14.09745  ? 147 GLN A H    1 
ATOM   2426 H HA   . GLN A 1 155 ? 3.83598   -5.93934  14.24984  1.000 13.44472  ? 147 GLN A HA   1 
ATOM   2427 H HB2  . GLN A 1 155 ? 3.49112   -8.72745  14.39485  1.000 23.17617  ? 147 GLN A HB2  1 
ATOM   2428 H HB3  . GLN A 1 155 ? 2.50533   -7.62177  14.97028  1.000 23.17617  ? 147 GLN A HB3  1 
ATOM   2429 H HG2  . GLN A 1 155 ? 1.71628   -7.18522  12.91425  1.000 34.08078  ? 147 GLN A HG2  1 
ATOM   2430 H HG3  . GLN A 1 155 ? 2.79714   -8.14567  12.25495  1.000 34.08078  ? 147 GLN A HG3  1 
ATOM   2431 H HE21 . GLN A 1 155 ? 0.76770   -9.10335  11.37608  1.000 21.00150  ? 147 GLN A HE21 1 
ATOM   2432 H HE22 . GLN A 1 155 ? 0.09467   -10.18658 12.14578  1.000 21.00150  ? 147 GLN A HE22 1 
ATOM   2433 N N    . PHE A 1 156 ? 4.60277   -6.84498  16.56954  1.000 12.29065  ? 148 PHE A N    1 
ATOM   2434 C CA   . PHE A 1 156 ? 5.29735   -7.04605  17.83810  1.000 11.39055  ? 148 PHE A CA   1 
ATOM   2435 C C    . PHE A 1 156 ? 4.32445   -7.78936  18.74313  1.000 11.27271  ? 148 PHE A C    1 
ATOM   2436 O O    . PHE A 1 156 ? 3.39080   -7.19359  19.29241  1.000 11.66303  ? 148 PHE A O    1 
ATOM   2437 C CB   . PHE A 1 156 ? 5.76613   -5.71240  18.39461  1.000 11.26931  ? 148 PHE A CB   1 
ATOM   2438 C CG   . PHE A 1 156 ? 6.78954   -5.06526  17.51191  1.000 9.12442   ? 148 PHE A CG   1 
ATOM   2439 C CD1  . PHE A 1 156 ? 6.39743   -4.40809  16.34280  1.000 13.25884  ? 148 PHE A CD1  1 
ATOM   2440 C CD2  . PHE A 1 156 ? 8.13817   -5.17969  17.78530  1.000 13.85973  ? 148 PHE A CD2  1 
ATOM   2441 C CE1  . PHE A 1 156 ? 7.31985   -3.85067  15.50629  1.000 12.97973  ? 148 PHE A CE1  1 
ATOM   2442 C CE2  . PHE A 1 156 ? 9.07879   -4.60957  16.94013  1.000 13.63292  ? 148 PHE A CE2  1 
ATOM   2443 C CZ   . PHE A 1 156 ? 8.67291   -3.95292  15.79759  1.000 12.99175  ? 148 PHE A CZ   1 
ATOM   2444 H H    . PHE A 1 156 ? 3.80509   -6.53981  16.67039  1.000 14.76581  ? 148 PHE A H    1 
ATOM   2445 H HA   . PHE A 1 156 ? 6.08623   -7.60196  17.74046  1.000 13.68568  ? 148 PHE A HA   1 
ATOM   2446 H HB2  . PHE A 1 156 ? 5.00683   -5.11336  18.46889  1.000 13.54020  ? 148 PHE A HB2  1 
ATOM   2447 H HB3  . PHE A 1 156 ? 6.16403   -5.85354  19.26791  1.000 13.54020  ? 148 PHE A HB3  1 
ATOM   2448 H HD1  . PHE A 1 156 ? 5.49361   -4.34976  16.13162  1.000 15.92763  ? 148 PHE A HD1  1 
ATOM   2449 H HD2  . PHE A 1 156 ? 8.41799   -5.64254  18.54186  1.000 16.64870  ? 148 PHE A HD2  1 
ATOM   2450 H HE1  . PHE A 1 156 ? 7.04183   -3.40201  14.74058  1.000 15.59270  ? 148 PHE A HE1  1 
ATOM   2451 H HE2  . PHE A 1 156 ? 9.98407   -4.67026  17.14429  1.000 16.37653  ? 148 PHE A HE2  1 
ATOM   2452 H HZ   . PHE A 1 156 ? 9.30333   -3.58005  15.22449  1.000 15.60712  ? 148 PHE A HZ   1 
ATOM   2453 N N    . SER A 1 157 ? 4.56687   -9.09851  18.89004  1.000 13.19892  ? 149 SER A N    1 
ATOM   2454 C CA   . SER A 1 157 ? 3.59699   -10.01131 19.48859  1.000 12.55934  ? 149 SER A CA   1 
ATOM   2455 C C    . SER A 1 157 ? 3.58761   -9.98207  21.00750  1.000 10.57644  ? 149 SER A C    1 
ATOM   2456 O O    . SER A 1 157 ? 2.66890   -10.54855 21.61144  1.000 11.42758  ? 149 SER A O    1 
ATOM   2457 C CB   . SER A 1 157 ? 3.86382   -11.44520 19.01688  1.000 18.03586  ? 149 SER A CB   1 
ATOM   2458 O OG   . SER A 1 157 ? 5.09964   -11.90557 19.51073  1.000 17.44546  ? 149 SER A OG   1 
ATOM   2459 H H    . SER A 1 157 ? 5.29640   -9.48332  18.64648  1.000 15.85572  ? 149 SER A H    1 
ATOM   2460 H HA   . SER A 1 157 ? 2.71394   -9.74744  19.18610  1.000 15.08823  ? 149 SER A HA   1 
ATOM   2461 H HB2  . SER A 1 157 ? 3.15668   -12.02320 19.34364  1.000 21.66006  ? 149 SER A HB2  1 
ATOM   2462 H HB3  . SER A 1 157 ? 3.88404   -11.46136 18.04722  1.000 21.66006  ? 149 SER A HB3  1 
ATOM   2463 H HG   . SER A 1 157 ? 5.72593   -11.44592 19.19121  1.000 20.95158  ? 149 SER A HG   1 
ATOM   2464 N N    . GLU A 1 158 ? 4.57885   -9.35936  21.62995  1.000 11.63198  ? 150 GLU A N    1 
ATOM   2465 C CA   . GLU A 1 158 ? 4.61435   -9.20345  23.07180  1.000 11.29766  ? 150 GLU A CA   1 
ATOM   2466 C C    . GLU A 1 158 ? 5.57062   -8.07452  23.39834  1.000 10.53649  ? 150 GLU A C    1 
ATOM   2467 O O    . GLU A 1 158 ? 6.42169   -7.70869  22.56338  1.000 11.69938  ? 150 GLU A O    1 
ATOM   2468 C CB   . GLU A 1 158 ? 5.04016   -10.50229 23.77766  1.000 14.97677  ? 150 GLU A CB   1 
ATOM   2469 C CG   . GLU A 1 158 ? 6.37807   -11.02579 23.40452  1.000 19.29464  ? 150 GLU A CG   1 
ATOM   2470 C CD   . GLU A 1 158 ? 6.75556   -12.26351 24.22879  1.000 34.36481  ? 150 GLU A CD   1 
ATOM   2471 O OE1  . GLU A 1 158 ? 6.50656   -12.26834 25.45592  1.000 29.31237  ? 150 GLU A OE1  1 
ATOM   2472 O OE2  . GLU A 1 158 ? 7.29655   -13.22966 23.65030  1.000 44.15673  ? 150 GLU A OE2  1 
ATOM   2473 H H    . GLU A 1 158 ? 5.25552   -9.01204  21.22860  1.000 13.97540  ? 150 GLU A H    1 
ATOM   2474 H HA   . GLU A 1 158 ? 3.73100   -8.96639  23.39492  1.000 13.57422  ? 150 GLU A HA   1 
ATOM   2475 H HB2  . GLU A 1 158 ? 5.05050   -10.34005 24.73394  1.000 17.98915  ? 150 GLU A HB2  1 
ATOM   2476 H HB3  . GLU A 1 158 ? 4.39141   -11.19136 23.56506  1.000 17.98915  ? 150 GLU A HB3  1 
ATOM   2477 H HG2  . GLU A 1 158 ? 6.37407   -11.27452 22.46697  1.000 23.17059  ? 150 GLU A HG2  1 
ATOM   2478 H HG3  . GLU A 1 158 ? 7.04543   -10.33990 23.56295  1.000 23.17059  ? 150 GLU A HG3  1 
ATOM   2479 N N    . PRO A 1 159 ? 5.45668   -7.49067  24.59366  1.000 12.29109  ? 151 PRO A N    1 
ATOM   2480 C CA   . PRO A 1 159 ? 6.31535   -6.33884  24.91764  1.000 10.25491  ? 151 PRO A CA   1 
ATOM   2481 C C    . PRO A 1 159 ? 7.79625   -6.63915  24.80023  1.000 10.64426  ? 151 PRO A C    1 
ATOM   2482 O O    . PRO A 1 159 ? 8.56740   -5.73734  24.46080  1.000 11.91589  ? 151 PRO A O    1 
ATOM   2483 C CB   . PRO A 1 159 ? 5.91849   -5.99039  26.36109  1.000 9.74867   ? 151 PRO A CB   1 
ATOM   2484 C CG   . PRO A 1 159 ? 4.49057   -6.49426  26.48372  1.000 12.54232  ? 151 PRO A CG   1 
ATOM   2485 C CD   . PRO A 1 159 ? 4.45386   -7.76161  25.64721  1.000 10.29626  ? 151 PRO A CD   1 
ATOM   2486 H HA   . PRO A 1 159 ? 6.09312   -5.59228  24.33959  1.000 12.32292  ? 151 PRO A HA   1 
ATOM   2487 H HB2  . PRO A 1 159 ? 6.50491   -6.44323  26.98714  1.000 11.71542  ? 151 PRO A HB2  1 
ATOM   2488 H HB3  . PRO A 1 159 ? 5.96460   -5.03117  26.49770  1.000 11.71542  ? 151 PRO A HB3  1 
ATOM   2489 H HG2  . PRO A 1 159 ? 4.28481   -6.68474  27.41231  1.000 15.06780  ? 151 PRO A HG2  1 
ATOM   2490 H HG3  . PRO A 1 159 ? 3.87392   -5.83081  26.13662  1.000 15.06780  ? 151 PRO A HG3  1 
ATOM   2491 H HD2  . PRO A 1 159 ? 4.70704   -8.53400  26.17657  1.000 12.37253  ? 151 PRO A HD2  1 
ATOM   2492 H HD3  . PRO A 1 159 ? 3.57409   -7.89743  25.26189  1.000 12.37253  ? 151 PRO A HD3  1 
ATOM   2493 N N    . LYS A 1 160 ? 8.22165   -7.86872  25.10533  1.000 9.74067   ? 152 LYS A N    1 
ATOM   2494 C CA   . LYS A 1 160 ? 9.62878   -8.24567  24.97810  1.000 10.74548  ? 152 LYS A CA   1 
ATOM   2495 C C    . LYS A 1 160 ? 10.15825  -8.02891  23.56862  1.000 12.58031  ? 152 LYS A C    1 
ATOM   2496 O O    . LYS A 1 160 ? 11.33716  -7.69102  23.39739  1.000 12.50136  ? 152 LYS A O    1 
ATOM   2497 C CB   . LYS A 1 160 ? 9.77465   -9.71220  25.39202  1.000 15.56763  ? 152 LYS A CB   1 
ATOM   2498 C CG   . LYS A 1 160 ? 11.13289  -10.32742 25.37134  1.000 31.90759  ? 152 LYS A CG   1 
ATOM   2499 C CD   . LYS A 1 160 ? 10.97309  -11.83224 25.70860  1.000 30.01645  ? 152 LYS A CD   1 
ATOM   2500 C CE   . LYS A 1 160 ? 12.29999  -12.55618 25.79039  1.000 48.43292  ? 152 LYS A CE   1 
ATOM   2501 N NZ   . LYS A 1 160 ? 12.15635  -13.78691 26.61749  1.000 40.11095  ? 152 LYS A NZ   1 
ATOM   2502 H H    . LYS A 1 160 ? 7.71482   -8.50324  25.38837  1.000 11.70583  ? 152 LYS A H    1 
ATOM   2503 H HA   . LYS A 1 160 ? 10.16775  -7.69339  25.56580  1.000 12.91159  ? 152 LYS A HA   1 
ATOM   2504 H HB2  . LYS A 1 160 ? 9.44948   -9.79339  26.30228  1.000 18.69818  ? 152 LYS A HB2  1 
ATOM   2505 H HB3  . LYS A 1 160 ? 9.22358   -10.24144 24.79442  1.000 18.69818  ? 152 LYS A HB3  1 
ATOM   2506 H HG2  . LYS A 1 160 ? 11.52935  -10.23637 24.49076  1.000 38.30613  ? 152 LYS A HG2  1 
ATOM   2507 H HG3  . LYS A 1 160 ? 11.70148  -9.90830  26.03613  1.000 38.30613  ? 152 LYS A HG3  1 
ATOM   2508 H HD2  . LYS A 1 160 ? 10.53065  -11.91917 26.56743  1.000 36.03676  ? 152 LYS A HD2  1 
ATOM   2509 H HD3  . LYS A 1 160 ? 10.44180  -12.25717 25.01718  1.000 36.03676  ? 152 LYS A HD3  1 
ATOM   2510 H HE2  . LYS A 1 160 ? 12.58914  -12.81087 24.90021  1.000 58.13653  ? 152 LYS A HE2  1 
ATOM   2511 H HE3  . LYS A 1 160 ? 12.96246  -11.97952 26.20209  1.000 58.13653  ? 152 LYS A HE3  1 
ATOM   2512 H HZ1  . LYS A 1 160 ? 12.93169  -14.22249 26.65228  1.000 48.15016  ? 152 LYS A HZ1  1 
ATOM   2513 H HZ2  . LYS A 1 160 ? 11.90920  -13.57063 27.44468  1.000 48.15016  ? 152 LYS A HZ2  1 
ATOM   2514 H HZ3  . LYS A 1 160 ? 11.54011  -14.32201 26.26252  1.000 48.15016  ? 152 LYS A HZ3  1 
ATOM   2515 N N    . GLU A 1 161 ? 9.30880   -8.19435  22.55207  1.000 13.38347  ? 153 GLU A N    1 
ATOM   2516 C CA   . GLU A 1 161 ? 9.75491   -7.98026  21.18014  1.000 13.05265  ? 153 GLU A CA   1 
ATOM   2517 C C    . GLU A 1 161 ? 10.10862  -6.51726  20.91392  1.000 12.45471  ? 153 GLU A C    1 
ATOM   2518 O O    . GLU A 1 161 ? 11.01564  -6.23942  20.11973  1.000 12.66997  ? 153 GLU A O    1 
ATOM   2519 C CB   . GLU A 1 161 ? 8.68650   -8.46568  20.20222  1.000 12.88974  ? 153 GLU A CB   1 
ATOM   2520 C CG   . GLU A 1 161 ? 8.40548   -9.96394  20.28461  1.000 12.99542  ? 153 GLU A CG   1 
ATOM   2521 C CD   . GLU A 1 161 ? 9.63543   -10.80465 20.04972  1.000 27.60824  ? 153 GLU A CD   1 
ATOM   2522 O OE1  . GLU A 1 161 ? 10.49562  -10.40393 19.24824  1.000 20.80848  ? 153 GLU A OE1  1 
ATOM   2523 O OE2  . GLU A 1 161 ? 9.74690   -11.87732 20.66900  1.000 38.23076  ? 153 GLU A OE2  1 
ATOM   2524 H H    . GLU A 1 161 ? 8.48432   -8.42602  22.63049  1.000 16.07718  ? 153 GLU A H    1 
ATOM   2525 H HA   . GLU A 1 161 ? 10.55731  -8.50390  21.02897  1.000 15.68021  ? 153 GLU A HA   1 
ATOM   2526 H HB2  . GLU A 1 161 ? 7.85732   -7.99893  20.39061  1.000 15.48471  ? 153 GLU A HB2  1 
ATOM   2527 H HB3  . GLU A 1 161 ? 8.97974   -8.26950  19.29865  1.000 15.48471  ? 153 GLU A HB3  1 
ATOM   2528 H HG2  . GLU A 1 161 ? 8.06409   -10.17298 21.16816  1.000 15.61153  ? 153 GLU A HG2  1 
ATOM   2529 H HG3  . GLU A 1 161 ? 7.74860   -10.19945 19.61086  1.000 15.61153  ? 153 GLU A HG3  1 
ATOM   2530 N N    . ILE A 1 162 ? 9.42874   -5.57527  21.58054  1.000 10.97804  ? 154 ILE A N    1 
ATOM   2531 C CA   . ILE A 1 162 ? 9.75934   -4.15933  21.42940  1.000 9.39408   ? 154 ILE A CA   1 
ATOM   2532 C C    . ILE A 1 162 ? 11.11832  -3.86611  22.04096  1.000 11.04596  ? 154 ILE A C    1 
ATOM   2533 O O    . ILE A 1 162 ? 11.93948  -3.15209  21.44868  1.000 12.96253  ? 154 ILE A O    1 
ATOM   2534 C CB   . ILE A 1 162 ? 8.65428   -3.28198  22.04737  1.000 11.19406  ? 154 ILE A CB   1 
ATOM   2535 C CG1  . ILE A 1 162 ? 7.31598   -3.61733  21.38899  1.000 12.53624  ? 154 ILE A CG1  1 
ATOM   2536 C CG2  . ILE A 1 162 ? 9.00315   -1.79191  21.88989  1.000 11.56233  ? 154 ILE A CG2  1 
ATOM   2537 C CD1  . ILE A 1 162 ? 6.11386   -2.90055  22.01712  1.000 10.92901  ? 154 ILE A CD1  1 
ATOM   2538 H H    . ILE A 1 162 ? 8.77808   -5.73095  22.12092  1.000 13.19067  ? 154 ILE A H    1 
ATOM   2539 H HA   . ILE A 1 162 ? 9.80684   -3.95268  20.48286  1.000 11.28992  ? 154 ILE A HA   1 
ATOM   2540 H HB   . ILE A 1 162 ? 8.58586   -3.46733  22.99704  1.000 13.44990  ? 154 ILE A HB   1 
ATOM   2541 H HG12 . ILE A 1 162 ? 7.35658   -3.36126  20.45428  1.000 15.06051  ? 154 ILE A HG12 1 
ATOM   2542 H HG13 . ILE A 1 162 ? 7.16274   -4.57212  21.46506  1.000 15.06051  ? 154 ILE A HG13 1 
ATOM   2543 H HG21 . ILE A 1 162 ? 8.28613   -1.25817  22.26657  1.000 13.89182  ? 154 ILE A HG21 1 
ATOM   2544 H HG22 . ILE A 1 162 ? 9.83236   -1.61039  22.35931  1.000 13.89182  ? 154 ILE A HG22 1 
ATOM   2545 H HG23 . ILE A 1 162 ? 9.10581   -1.58957  20.94680  1.000 13.89182  ? 154 ILE A HG23 1 
ATOM   2546 H HD11 . ILE A 1 162 ? 5.29837   -3.24445  21.62014  1.000 13.13184  ? 154 ILE A HD11 1 
ATOM   2547 H HD12 . ILE A 1 162 ? 6.11173   -3.06584  22.97293  1.000 13.13184  ? 154 ILE A HD12 1 
ATOM   2548 H HD13 . ILE A 1 162 ? 6.18911   -1.94869  21.84621  1.000 13.13184  ? 154 ILE A HD13 1 
ATOM   2549 N N    . ALA A 1 163 ? 11.39815  -4.43552  23.22233  1.000 10.58477  ? 155 ALA A N    1 
ATOM   2550 C CA   . ALA A 1 163 ? 12.70557  -4.24084  23.83496  1.000 13.04560  ? 155 ALA A CA   1 
ATOM   2551 C C    . ALA A 1 163 ? 13.81219  -4.86575  22.99361  1.000 9.57828   ? 155 ALA A C    1 
ATOM   2552 O O    . ALA A 1 163 ? 14.89433  -4.28682  22.85088  1.000 13.19967  ? 155 ALA A O    1 
ATOM   2553 C CB   . ALA A 1 163 ? 12.71722  -4.81910  25.24934  1.000 15.54204  ? 155 ALA A CB   1 
ATOM   2554 H H    . ALA A 1 163 ? 10.85672  -4.92708  23.67489  1.000 12.71874  ? 155 ALA A H    1 
ATOM   2555 H HA   . ALA A 1 163 ? 12.87820  -3.28843  23.89833  1.000 15.67175  ? 155 ALA A HA   1 
ATOM   2556 H HB1  . ALA A 1 163 ? 13.59247  -4.67547  25.64204  1.000 18.66747  ? 155 ALA A HB1  1 
ATOM   2557 H HB2  . ALA A 1 163 ? 12.03938  -4.37117  25.77924  1.000 18.66747  ? 155 ALA A HB2  1 
ATOM   2558 H HB3  . ALA A 1 163 ? 12.52703  -5.76917  25.20366  1.000 18.66747  ? 155 ALA A HB3  1 
ATOM   2559 N N    . ARG A 1 164 ? 13.56330  -6.05487  22.43343  1.000 10.92075  ? 156 ARG A N    1 
ATOM   2560 C CA   . ARG A 1 164 ? 14.54528  -6.69440  21.56288  1.000 11.56415  ? 156 ARG A CA   1 
ATOM   2561 C C    . ARG A 1 164 ? 14.83088  -5.83815  20.33164  1.000 13.48834  ? 156 ARG A C    1 
ATOM   2562 O O    . ARG A 1 164 ? 15.99209  -5.61027  19.96702  1.000 14.68604  ? 156 ARG A O    1 
ATOM   2563 C CB   . ARG A 1 164 ? 14.04018  -8.08334  21.16114  1.000 11.07578  ? 156 ARG A CB   1 
ATOM   2564 C CG   . ARG A 1 164 ? 14.90362  -8.74372  20.10994  1.000 18.33960  ? 156 ARG A CG   1 
ATOM   2565 C CD   . ARG A 1 164 ? 14.81243  -10.23895 20.14028  1.000 33.49131  ? 156 ARG A CD   1 
ATOM   2566 N NE   . ARG A 1 164 ? 13.57878  -10.72493 19.54602  1.000 26.25020  ? 156 ARG A NE   1 
ATOM   2567 C CZ   . ARG A 1 164 ? 13.46014  -11.88879 18.90644  1.000 30.03044  ? 156 ARG A CZ   1 
ATOM   2568 N NH1  . ARG A 1 164 ? 14.49874  -12.70335 18.78107  1.000 29.38245  ? 156 ARG A NH1  1 
ATOM   2569 N NH2  . ARG A 1 164 ? 12.29187  -12.25413 18.40292  1.000 22.95193  ? 156 ARG A NH2  1 
ATOM   2570 H H    . ARG A 1 164 ? 12.83918  -6.50588  22.54223  1.000 13.12193  ? 156 ARG A H    1 
ATOM   2571 H HA   . ARG A 1 164 ? 15.38004  -6.80122  22.04524  1.000 13.89401  ? 156 ARG A HA   1 
ATOM   2572 H HB2  . ARG A 1 164 ? 14.03297  -8.65465  21.94501  1.000 13.30796  ? 156 ARG A HB2  1 
ATOM   2573 H HB3  . ARG A 1 164 ? 13.14264  -8.00048  20.80274  1.000 13.30796  ? 156 ARG A HB3  1 
ATOM   2574 H HG2  . ARG A 1 164 ? 14.61876  -8.44405  19.23247  1.000 22.02454  ? 156 ARG A HG2  1 
ATOM   2575 H HG3  . ARG A 1 164 ? 15.82960  -8.49704  20.26032  1.000 22.02454  ? 156 ARG A HG3  1 
ATOM   2576 H HD2  . ARG A 1 164 ? 15.55587  -10.61362 19.64247  1.000 40.20660  ? 156 ARG A HD2  1 
ATOM   2577 H HD3  . ARG A 1 164 ? 14.84392  -10.54141 21.06138  1.000 40.20660  ? 156 ARG A HD3  1 
ATOM   2578 H HE   . ARG A 1 164 ? 12.87904  -10.22922 19.61111  1.000 31.51726  ? 156 ARG A HE   1 
ATOM   2579 H HH11 . ARG A 1 164 ? 15.26042  -12.48339 19.11434  1.000 35.27597  ? 156 ARG A HH11 1 
ATOM   2580 H HH12 . ARG A 1 164 ? 14.41074  -13.45166 18.36648  1.000 35.27597  ? 156 ARG A HH12 1 
ATOM   2581 H HH21 . ARG A 1 164 ? 11.60740  -11.74045 18.48797  1.000 27.55934  ? 156 ARG A HH21 1 
ATOM   2582 H HH22 . ARG A 1 164 ? 12.21724  -13.00520 17.99070  1.000 27.55934  ? 156 ARG A HH22 1 
ATOM   2583 N N    . PHE A 1 165 ? 13.77446  -5.31487  19.70842  1.000 12.34208  ? 157 PHE A N    1 
ATOM   2584 C CA   . PHE A 1 165 ? 13.92651  -4.40495  18.57343  1.000 11.32034  ? 157 PHE A CA   1 
ATOM   2585 C C    . PHE A 1 165 ? 14.77659  -3.19783  18.95494  1.000 10.12238  ? 157 PHE A C    1 
ATOM   2586 O O    . PHE A 1 165 ? 15.72330  -2.83186  18.24088  1.000 12.47130  ? 157 PHE A O    1 
ATOM   2587 C CB   . PHE A 1 165 ? 12.52185  -3.99749  18.09079  1.000 13.23686  ? 157 PHE A CB   1 
ATOM   2588 C CG   . PHE A 1 165 ? 12.49484  -2.88108  17.08925  1.000 12.55399  ? 157 PHE A CG   1 
ATOM   2589 C CD1  . PHE A 1 165 ? 12.88392  -3.09051  15.77354  1.000 12.01319  ? 157 PHE A CD1  1 
ATOM   2590 C CD2  . PHE A 1 165 ? 12.03610  -1.62606  17.45137  1.000 12.85885  ? 157 PHE A CD2  1 
ATOM   2591 C CE1  . PHE A 1 165 ? 12.83747  -2.06052  14.85076  1.000 12.82489  ? 157 PHE A CE1  1 
ATOM   2592 C CE2  . PHE A 1 165 ? 11.99920  -0.59692  16.53598  1.000 13.41401  ? 157 PHE A CE2  1 
ATOM   2593 C CZ   . PHE A 1 165 ? 12.40313  -0.80336  15.24863  1.000 13.11554  ? 157 PHE A CZ   1 
ATOM   2594 H H    . PHE A 1 165 ? 12.95639  -5.47061  19.92313  1.000 14.82751  ? 157 PHE A H    1 
ATOM   2595 H HA   . PHE A 1 165 ? 14.38366  -4.84524  17.83990  1.000 13.60143  ? 157 PHE A HA   1 
ATOM   2596 H HB2  . PHE A 1 165 ? 12.10335  -4.76890  17.67765  1.000 15.90126  ? 157 PHE A HB2  1 
ATOM   2597 H HB3  . PHE A 1 165 ? 12.00413  -3.71110  18.85945  1.000 15.90126  ? 157 PHE A HB3  1 
ATOM   2598 H HD1  . PHE A 1 165 ? 13.17896  -3.93197  15.50937  1.000 14.43285  ? 157 PHE A HD1  1 
ATOM   2599 H HD2  . PHE A 1 165 ? 11.74931  -1.47579  18.32319  1.000 15.44764  ? 157 PHE A HD2  1 
ATOM   2600 H HE1  . PHE A 1 165 ? 13.09553  -2.20942  13.96977  1.000 15.40689  ? 157 PHE A HE1  1 
ATOM   2601 H HE2  . PHE A 1 165 ? 11.69735  0.24319   16.79675  1.000 16.11384  ? 157 PHE A HE2  1 
ATOM   2602 H HZ   . PHE A 1 165 ? 12.38739  -0.10199  14.63812  1.000 15.75567  ? 157 PHE A HZ   1 
ATOM   2603 N N    . ILE A 1 166 ? 14.46768  -2.57376  20.09199  1.000 12.29909  ? 158 ILE A N    1 
ATOM   2604 C CA   . ILE A 1 166 ? 15.18432  -1.36655  20.48171  1.000 10.44496  ? 158 ILE A CA   1 
ATOM   2605 C C    . ILE A 1 166 ? 16.63327  -1.69376  20.80783  1.000 12.21308  ? 158 ILE A C    1 
ATOM   2606 O O    . ILE A 1 166 ? 17.55674  -1.03529  20.32090  1.000 14.83120  ? 158 ILE A O    1 
ATOM   2607 C CB   . ILE A 1 166 ? 14.47576  -0.67773  21.65930  1.000 10.41283  ? 158 ILE A CB   1 
ATOM   2608 C CG1  . ILE A 1 166 ? 13.13636  -0.10381  21.16849  1.000 11.67392  ? 158 ILE A CG1  1 
ATOM   2609 C CG2  . ILE A 1 166 ? 15.36585  0.40011   22.27030  1.000 13.49509  ? 158 ILE A CG2  1 
ATOM   2610 C CD1  . ILE A 1 166 ? 12.17948  0.34109   22.26118  1.000 15.16966  ? 158 ILE A CD1  1 
ATOM   2611 H H    . ILE A 1 166 ? 13.85817  -2.82593  20.64381  1.000 14.77593  ? 158 ILE A H    1 
ATOM   2612 H HA   . ILE A 1 166 ? 15.18092  -0.74959  19.73322  1.000 12.55097  ? 158 ILE A HA   1 
ATOM   2613 H HB   . ILE A 1 166 ? 14.29872  -1.32668  22.35817  1.000 12.51242  ? 158 ILE A HB   1 
ATOM   2614 H HG12 . ILE A 1 166 ? 13.32053  0.66967   20.61288  1.000 14.02573  ? 158 ILE A HG12 1 
ATOM   2615 H HG13 . ILE A 1 166 ? 12.68392  -0.78597  20.64806  1.000 14.02573  ? 158 ILE A HG13 1 
ATOM   2616 H HG21 . ILE A 1 166 ? 14.83756  0.93677   22.88170  1.000 16.21114  ? 158 ILE A HG21 1 
ATOM   2617 H HG22 . ILE A 1 166 ? 16.09433  -0.02570  22.74873  1.000 16.21114  ? 158 ILE A HG22 1 
ATOM   2618 H HG23 . ILE A 1 166 ? 15.71842  0.95863   21.55991  1.000 16.21114  ? 158 ILE A HG23 1 
ATOM   2619 H HD11 . ILE A 1 166 ? 11.34810  0.63097   21.85414  1.000 18.22062  ? 158 ILE A HD11 1 
ATOM   2620 H HD12 . ILE A 1 166 ? 12.01294  -0.40508  22.85818  1.000 18.22062  ? 158 ILE A HD12 1 
ATOM   2621 H HD13 . ILE A 1 166 ? 12.58060  1.07484   22.75272  1.000 18.22062  ? 158 ILE A HD13 1 
ATOM   2622 N N    . ASP A 1 167 ? 16.85265  -2.70498  21.65273  1.000 12.18974  ? 159 ASP A N    1 
ATOM   2623 C CA   . ASP A 1 167 ? 18.20544  -3.00582  22.11856  1.000 10.86758  ? 159 ASP A CA   1 
ATOM   2624 C C    . ASP A 1 167 ? 19.11916  -3.41297  20.96939  1.000 17.71601  ? 159 ASP A C    1 
ATOM   2625 O O    . ASP A 1 167 ? 20.29895  -3.03057  20.93758  1.000 17.54288  ? 159 ASP A O    1 
ATOM   2626 C CB   . ASP A 1 167 ? 18.14376  -4.11082  23.17703  1.000 13.15870  ? 159 ASP A CB   1 
ATOM   2627 C CG   . ASP A 1 167 ? 19.40341  -4.19468  24.02570  1.000 19.48040  ? 159 ASP A CG   1 
ATOM   2628 O OD1  . ASP A 1 167 ? 19.88369  -3.14535  24.47898  1.000 18.40661  ? 159 ASP A OD1  1 
ATOM   2629 O OD2  . ASP A 1 167 ? 19.89888  -5.31844  24.23981  1.000 27.74288  ? 159 ASP A OD2  1 
ATOM   2630 H H    . ASP A 1 167 ? 16.24345  -3.22457  21.96660  1.000 14.64471  ? 159 ASP A H    1 
ATOM   2631 H HA   . ASP A 1 167 ? 18.58448  -2.20972  22.52286  1.000 13.05812  ? 159 ASP A HA   1 
ATOM   2632 H HB2  . ASP A 1 167 ? 17.39552  -3.93781  23.76957  1.000 15.80747  ? 159 ASP A HB2  1 
ATOM   2633 H HB3  . ASP A 1 167 ? 18.02510  -4.96532  22.73358  1.000 15.80747  ? 159 ASP A HB3  1 
ATOM   2634 N N    . VAL A 1 168 ? 18.60008  -4.18756  20.01364  1.000 12.83478  ? 160 VAL A N    1 
ATOM   2635 C CA   . VAL A 1 168 ? 19.46410  -4.74306  18.97535  1.000 15.33545  ? 160 VAL A CA   1 
ATOM   2636 C C    . VAL A 1 168 ? 19.69589  -3.75053  17.84009  1.000 19.73775  ? 160 VAL A C    1 
ATOM   2637 O O    . VAL A 1 168 ? 20.79875  -3.69406  17.28150  1.000 16.07201  ? 160 VAL A O    1 
ATOM   2638 C CB   . VAL A 1 168 ? 18.88407  -6.06883  18.44962  1.000 14.22190  ? 160 VAL A CB   1 
ATOM   2639 C CG1  . VAL A 1 168 ? 19.66690  -6.57350  17.23697  1.000 14.58617  ? 160 VAL A CG1  1 
ATOM   2640 C CG2  . VAL A 1 168 ? 18.86917  -7.12031  19.57103  1.000 17.32762  ? 160 VAL A CG2  1 
ATOM   2641 H H    . VAL A 1 168 ? 17.76966  -4.40091  19.94660  1.000 15.41876  ? 160 VAL A H    1 
ATOM   2642 H HA   . VAL A 1 168 ? 20.32641  -4.92484  19.38065  1.000 18.41956  ? 160 VAL A HA   1 
ATOM   2643 H HB   . VAL A 1 168 ? 17.97110  -5.91655  18.15947  1.000 17.08331  ? 160 VAL A HB   1 
ATOM   2644 H HG11 . VAL A 1 168 ? 19.41050  -7.49117  17.05516  1.000 17.52043  ? 160 VAL A HG11 1 
ATOM   2645 H HG12 . VAL A 1 168 ? 19.45931  -6.01431  16.47204  1.000 17.52043  ? 160 VAL A HG12 1 
ATOM   2646 H HG13 . VAL A 1 168 ? 20.61591  -6.52773  17.43235  1.000 17.52043  ? 160 VAL A HG13 1 
ATOM   2647 H HG21 . VAL A 1 168 ? 18.56669  -7.96671  19.20632  1.000 20.81017  ? 160 VAL A HG21 1 
ATOM   2648 H HG22 . VAL A 1 168 ? 19.76654  -7.21525  19.92686  1.000 20.81017  ? 160 VAL A HG22 1 
ATOM   2649 H HG23 . VAL A 1 168 ? 18.26511  -6.82696  20.27099  1.000 20.81017  ? 160 VAL A HG23 1 
ATOM   2650 N N    . PHE A 1 169 ? 18.68099  -2.95621  17.47165  1.000 14.06378  ? 161 PHE A N    1 
ATOM   2651 C CA   . PHE A 1 169 ? 18.74527  -2.16707  16.24395  1.000 13.87341  ? 161 PHE A CA   1 
ATOM   2652 C C    . PHE A 1 169 ? 18.73941  -0.65600  16.45261  1.000 19.07854  ? 161 PHE A C    1 
ATOM   2653 O O    . PHE A 1 169 ? 19.06255  0.07443   15.50569  1.000 17.16480  ? 161 PHE A O    1 
ATOM   2654 C CB   . PHE A 1 169 ? 17.57900  -2.53625  15.29569  1.000 11.19109  ? 161 PHE A CB   1 
ATOM   2655 C CG   . PHE A 1 169 ? 17.51478  -3.99763  14.93496  1.000 11.76376  ? 161 PHE A CG   1 
ATOM   2656 C CD1  . PHE A 1 169 ? 18.47794  -4.57089  14.12645  1.000 14.13073  ? 161 PHE A CD1  1 
ATOM   2657 C CD2  . PHE A 1 169 ? 16.48536  -4.79929  15.39295  1.000 10.06109  ? 161 PHE A CD2  1 
ATOM   2658 C CE1  . PHE A 1 169 ? 18.41603  -5.91879  13.79340  1.000 10.37195  ? 161 PHE A CE1  1 
ATOM   2659 C CE2  . PHE A 1 169 ? 16.43466  -6.15814  15.07530  1.000 13.24883  ? 161 PHE A CE2  1 
ATOM   2660 C CZ   . PHE A 1 169 ? 17.39487  -6.70826  14.26204  1.000 12.49292  ? 161 PHE A CZ   1 
ATOM   2661 H H    . PHE A 1 169 ? 17.95119  -2.86136  17.91661  1.000 16.89355  ? 161 PHE A H    1 
ATOM   2662 H HA   . PHE A 1 169 ? 19.57837  -2.39080  15.80034  1.000 16.66511  ? 161 PHE A HA   1 
ATOM   2663 H HB2  . PHE A 1 169 ? 16.74240  -2.30290  15.72761  1.000 13.44634  ? 161 PHE A HB2  1 
ATOM   2664 H HB3  . PHE A 1 169 ? 17.67837  -2.03404  14.47179  1.000 13.44634  ? 161 PHE A HB3  1 
ATOM   2665 H HD1  . PHE A 1 169 ? 19.17552  -4.04869  13.80151  1.000 16.97390  ? 161 PHE A HD1  1 
ATOM   2666 H HD2  . PHE A 1 169 ? 15.81611  -4.42752  15.92095  1.000 12.09033  ? 161 PHE A HD2  1 
ATOM   2667 H HE1  . PHE A 1 169 ? 19.07207  -6.28939  13.24826  1.000 12.46336  ? 161 PHE A HE1  1 
ATOM   2668 H HE2  . PHE A 1 169 ? 15.75126  -6.69014  15.41419  1.000 15.91562  ? 161 PHE A HE2  1 
ATOM   2669 H HZ   . PHE A 1 169 ? 17.35387  -7.60806  14.03059  1.000 15.00853  ? 161 PHE A HZ   1 
ATOM   2670 N N    . CYS A 1 170 ? 18.40438  -0.15310  17.64621  1.000 15.97009  ? 162 CYS A N    1 
ATOM   2671 C CA   . CYS A 1 170 ? 18.15374  1.27411   17.79213  1.000 14.34731  ? 162 CYS A CA   1 
ATOM   2672 C C    . CYS A 1 170 ? 19.12956  2.00259   18.70250  1.000 17.51876  ? 162 CYS A C    1 
ATOM   2673 O O    . CYS A 1 170 ? 19.07059  3.23241   18.76961  1.000 21.44636  ? 162 CYS A O    1 
ATOM   2674 C CB   . CYS A 1 170 ? 16.72042  1.51739   18.30086  1.000 13.96631  ? 162 CYS A CB   1 
ATOM   2675 S SG   . CYS A 1 170 ? 15.41232  0.73019   17.30325  1.000 17.06916  ? 162 CYS A SG   1 
ATOM   2676 H H    . CYS A 1 170 ? 18.31920  -0.61331  18.36770  1.000 19.18113  ? 162 CYS A H    1 
ATOM   2677 H HA   . CYS A 1 170 ? 18.23441  1.67889   16.91432  1.000 17.23379  ? 162 CYS A HA   1 
ATOM   2678 H HB2  . CYS A 1 170 ? 16.65031  1.16739   19.20279  1.000 16.77660  ? 162 CYS A HB2  1 
ATOM   2679 H HB3  . CYS A 1 170 ? 16.55203  2.47266   18.30167  1.000 16.77660  ? 162 CYS A HB3  1 
ATOM   2680 H HG   . CYS A 1 170 ? 14.34333  1.00376   17.77487  1.000 20.50001  ? 162 CYS A HG   1 
ATOM   2681 N N    . LEU A 1 171 ? 20.03316  1.30509   19.37984  1.000 20.55182  ? 163 LEU A N    1 
ATOM   2682 C CA   . LEU A 1 171 ? 20.92753  1.95138   20.32956  1.000 24.90322  ? 163 LEU A CA   1 
ATOM   2683 C C    . LEU A 1 171 ? 22.36314  2.08113   19.83630  1.000 31.61023  ? 163 LEU A C    1 
ATOM   2684 O O    . LEU A 1 171 ? 23.15328  2.78163   20.47851  1.000 46.83851  ? 163 LEU A O    1 
ATOM   2685 C CB   . LEU A 1 171 ? 20.92065  1.18893   21.66489  1.000 23.37856  ? 163 LEU A CB   1 
ATOM   2686 C CG   . LEU A 1 171 ? 19.55514  0.96565   22.31558  1.000 22.08329  ? 163 LEU A CG   1 
ATOM   2687 C CD1  . LEU A 1 171 ? 19.68526  0.28363   23.66843  1.000 22.94318  ? 163 LEU A CD1  1 
ATOM   2688 C CD2  . LEU A 1 171 ? 18.79600  2.27287   22.45987  1.000 26.71836  ? 163 LEU A CD2  1 
ATOM   2689 H H    . LEU A 1 171 ? 20.14728  0.45587   19.30633  1.000 24.67920  ? 163 LEU A H    1 
ATOM   2690 H HA   . LEU A 1 171 ? 20.59831  2.84884   20.49410  1.000 29.90089  ? 163 LEU A HA   1 
ATOM   2691 H HB2  . LEU A 1 171 ? 21.31073  0.31385   21.51327  1.000 28.07130  ? 163 LEU A HB2  1 
ATOM   2692 H HB3  . LEU A 1 171 ? 21.46022  1.68744   22.29833  1.000 28.07130  ? 163 LEU A HB3  1 
ATOM   2693 H HG   . LEU A 1 171 ? 19.04466  0.37978   21.73500  1.000 26.51698  ? 163 LEU A HG   1 
ATOM   2694 H HD11 . LEU A 1 171 ? 18.80042  0.15991   24.04612  1.000 27.54884  ? 163 LEU A HD11 1 
ATOM   2695 H HD12 . LEU A 1 171 ? 20.11684  -0.57670  23.54817  1.000 27.54884  ? 163 LEU A HD12 1 
ATOM   2696 H HD13 . LEU A 1 171 ? 20.21959  0.84278   24.25388  1.000 27.54884  ? 163 LEU A HD13 1 
ATOM   2697 H HD21 . LEU A 1 171 ? 17.98185  2.11151   22.96189  1.000 32.07906  ? 163 LEU A HD21 1 
ATOM   2698 H HD22 . LEU A 1 171 ? 19.35381  2.91168   22.93070  1.000 32.07906  ? 163 LEU A HD22 1 
ATOM   2699 H HD23 . LEU A 1 171 ? 18.57873  2.61099   21.57705  1.000 32.07906  ? 163 LEU A HD23 1 
ATOM   2700 N N    . ARG A 1 172 ? 22.72401  1.44231   18.72682  1.000 28.26024  ? 164 ARG A N    1 
ATOM   2701 C CA   . ARG A 1 172 ? 24.07418  1.54163   18.18958  1.000 35.30861  ? 164 ARG A CA   1 
ATOM   2702 C C    . ARG A 1 172 ? 24.24660  2.82699   17.39005  1.000 26.63365  ? 164 ARG A C    1 
ATOM   2703 O O    . ARG A 1 172 ? 23.30164  3.34074   16.78544  1.000 29.08414  ? 164 ARG A O    1 
ATOM   2704 C CB   . ARG A 1 172 ? 24.38546  0.33835   17.29446  1.000 49.29409  ? 164 ARG A CB   1 
ATOM   2705 C CG   . ARG A 1 172 ? 24.66352  -0.95620  18.05540  1.000 71.90919  ? 164 ARG A CG   1 
ATOM   2706 C CD   . ARG A 1 172 ? 25.64773  -1.85040  17.30612  1.000 73.60504  ? 164 ARG A CD   1 
ATOM   2707 N NE   . ARG A 1 172 ? 26.99985  -1.73795  17.84884  1.000 82.96382  ? 164 ARG A NE   1 
ATOM   2708 C CZ   . ARG A 1 172 ? 28.10779  -1.71034  17.11360  1.000 81.70375  ? 164 ARG A CZ   1 
ATOM   2709 N NH1  . ARG A 1 172 ? 28.03753  -1.79573  15.79115  1.000 65.85655  ? 164 ARG A NH1  1 
ATOM   2710 N NH2  . ARG A 1 172 ? 29.29162  -1.60149  17.70340  1.000 72.61623  ? 164 ARG A NH2  1 
ATOM   2711 H H    . ARG A 1 172 ? 22.20034  0.94132   18.26382  1.000 33.92931  ? 164 ARG A H    1 
ATOM   2712 H HA   . ARG A 1 172 ? 24.70809  1.55138   18.92372  1.000 42.38736  ? 164 ARG A HA   1 
ATOM   2713 H HB2  . ARG A 1 172 ? 23.62522  0.17994   16.71322  1.000 59.16993  ? 164 ARG A HB2  1 
ATOM   2714 H HB3  . ARG A 1 172 ? 25.17172  0.54209   16.76420  1.000 59.16993  ? 164 ARG A HB3  1 
ATOM   2715 H HG2  . ARG A 1 172 ? 25.04472  -0.74339  18.92160  1.000 86.30806  ? 164 ARG A HG2  1 
ATOM   2716 H HG3  . ARG A 1 172 ? 23.83387  -1.44571  18.16926  1.000 86.30806  ? 164 ARG A HG3  1 
ATOM   2717 H HD2  . ARG A 1 172 ? 25.36432  -2.77478  17.38424  1.000 88.34308  ? 164 ARG A HD2  1 
ATOM   2718 H HD3  . ARG A 1 172 ? 25.67178  -1.58854  16.37245  1.000 88.34308  ? 164 ARG A HD3  1 
ATOM   2719 H HE   . ARG A 1 172 ? 27.08511  -1.68602  18.70303  1.000 99.57361  ? 164 ARG A HE   1 
ATOM   2720 H HH11 . ARG A 1 172 ? 27.27261  -1.86939  15.40504  1.000 79.04489  ? 164 ARG A HH11 1 
ATOM   2721 H HH12 . ARG A 1 172 ? 28.75692  -1.77741  15.32025  1.000 79.04489  ? 164 ARG A HH12 1 
ATOM   2722 H HH21 . ARG A 1 172 ? 29.34190  -1.54888  18.56031  1.000 87.15650  ? 164 ARG A HH21 1 
ATOM   2723 H HH22 . ARG A 1 172 ? 30.00852  -1.58357  17.22869  1.000 87.15650  ? 164 ARG A HH22 1 
ATOM   2724 N N    . GLU A 1 173 ? 25.48183  3.33355   17.36750  1.000 25.32018  ? 165 GLU A N    1 
ATOM   2725 C CA   . GLU A 1 173 ? 25.76197  4.55039   16.61476  1.000 38.56526  ? 165 GLU A CA   1 
ATOM   2726 C C    . GLU A 1 173 ? 25.54514  4.34025   15.12118  1.000 28.35788  ? 165 GLU A C    1 
ATOM   2727 O O    . GLU A 1 173 ? 25.03950  5.22968   14.42517  1.000 31.14925  ? 165 GLU A O    1 
ATOM   2728 C CB   . GLU A 1 173 ? 27.19733  5.00793   16.86875  1.000 54.62158  ? 165 GLU A CB   1 
ATOM   2729 C CG   . GLU A 1 173 ? 27.55492  5.22168   18.32635  1.000 95.60219  ? 165 GLU A CG   1 
ATOM   2730 C CD   . GLU A 1 173 ? 28.87377  5.95576   18.49323  1.000 85.08321  ? 165 GLU A CD   1 
ATOM   2731 O OE1  . GLU A 1 173 ? 28.95102  7.13916   18.10131  1.000 71.90480  ? 165 GLU A OE1  1 
ATOM   2732 O OE2  . GLU A 1 173 ? 29.83363  5.34852   19.01246  1.000 71.71943  ? 165 GLU A OE2  1 
ATOM   2733 H H    . GLU A 1 173 ? 26.16125  2.99640   17.77287  1.000 30.40123  ? 165 GLU A H    1 
ATOM   2734 H HA   . GLU A 1 173 ? 25.15748  5.24489   16.91997  1.000 46.29533  ? 165 GLU A HA   1 
ATOM   2735 H HB2  . GLU A 1 173 ? 27.80062  4.33454   16.51733  1.000 65.56292  ? 165 GLU A HB2  1 
ATOM   2736 H HB3  . GLU A 1 173 ? 27.33656  5.85055   16.40886  1.000 65.56292  ? 165 GLU A HB3  1 
ATOM   2737 H HG2  . GLU A 1 173 ? 26.85991  5.74907   18.75029  1.000 114.73965 ? 165 GLU A HG2  1 
ATOM   2738 H HG3  . GLU A 1 173 ? 27.63135  4.35980   18.76477  1.000 114.73965 ? 165 GLU A HG3  1 
ATOM   2739 N N    . GLN A 1 174 ? 25.92715  3.17665   14.60595  1.000 27.95244  ? 166 GLN A N    1 
ATOM   2740 C CA   . GLN A 1 174 ? 25.90909  2.92307   13.17217  1.000 28.47036  ? 166 GLN A CA   1 
ATOM   2741 C C    . GLN A 1 174 ? 24.62459  2.19199   12.79736  1.000 16.46856  ? 166 GLN A C    1 
ATOM   2742 O O    . GLN A 1 174 ? 24.40257  1.05787   13.22517  1.000 25.04242  ? 166 GLN A O    1 
ATOM   2743 C CB   . GLN A 1 174 ? 27.13449  2.11058   12.74674  1.000 33.25072  ? 166 GLN A CB   1 
ATOM   2744 C CG   . GLN A 1 174 ? 28.44407  2.89513   12.71315  1.000 50.61714  ? 166 GLN A CG   1 
ATOM   2745 C CD   . GLN A 1 174 ? 28.26178  4.36913   12.36144  1.000 62.65287  ? 166 GLN A CD   1 
ATOM   2746 O OE1  . GLN A 1 174 ? 27.88390  4.71363   11.23764  1.000 46.74323  ? 166 GLN A OE1  1 
ATOM   2747 N NE2  . GLN A 1 174 ? 28.52243  5.24353   13.32730  1.000 73.20207  ? 166 GLN A NE2  1 
ATOM   2748 H H    . GLN A 1 174 ? 26.20431  2.51058   15.07406  1.000 33.55995  ? 166 GLN A H    1 
ATOM   2749 H HA   . GLN A 1 174 ? 25.92158  3.77059   12.70054  1.000 34.18145  ? 166 GLN A HA   1 
ATOM   2750 H HB2  . GLN A 1 174 ? 27.24968  1.37765   13.37159  1.000 39.91788  ? 166 GLN A HB2  1 
ATOM   2751 H HB3  . GLN A 1 174 ? 26.97916  1.76423   11.85410  1.000 39.91788  ? 166 GLN A HB3  1 
ATOM   2752 H HG2  . GLN A 1 174 ? 28.85992  2.84807   13.58822  1.000 60.75759  ? 166 GLN A HG2  1 
ATOM   2753 H HG3  . GLN A 1 174 ? 29.02828  2.50105   12.04658  1.000 60.75759  ? 166 GLN A HG3  1 
ATOM   2754 H HE21 . GLN A 1 174 ? 28.77862  4.96681   14.10021  1.000 87.85950  ? 166 GLN A HE21 1 
ATOM   2755 H HE22 . GLN A 1 174 ? 28.43495  6.08621   13.17954  1.000 87.85950  ? 166 GLN A HE22 1 
ATOM   2756 N N    . LEU A 1 175 ? 23.79276  2.84443   11.99090  1.000 15.19443  ? 167 LEU A N    1 
ATOM   2757 C CA   . LEU A 1 175 ? 22.60033  2.23063   11.42257  1.000 16.83173  ? 167 LEU A CA   1 
ATOM   2758 C C    . LEU A 1 175 ? 22.88151  1.55563   10.08696  1.000 13.91071  ? 167 LEU A C    1 
ATOM   2759 O O    . LEU A 1 175 ? 22.17702  0.61111   9.70304   1.000 16.58918  ? 167 LEU A O    1 
ATOM   2760 C CB   . LEU A 1 175 ? 21.53026  3.30083   11.23917  1.000 17.60090  ? 167 LEU A CB   1 
ATOM   2761 C CG   . LEU A 1 175 ? 21.07471  3.99075   12.53351  1.000 18.27802  ? 167 LEU A CG   1 
ATOM   2762 C CD1  . LEU A 1 175 ? 20.20529  5.20212   12.21547  1.000 16.83502  ? 167 LEU A CD1  1 
ATOM   2763 C CD2  . LEU A 1 175 ? 20.35367  3.00386   13.40472  1.000 18.48906  ? 167 LEU A CD2  1 
ATOM   2764 H H    . LEU A 1 175 ? 23.90031  3.66365   11.75233  1.000 18.25034  ? 167 LEU A H    1 
ATOM   2765 H HA   . LEU A 1 175 ? 22.25704  1.55520   12.02825  1.000 20.21509  ? 167 LEU A HA   1 
ATOM   2766 H HB2  . LEU A 1 175 ? 21.88125  3.98743   10.65071  1.000 21.13811  ? 167 LEU A HB2  1 
ATOM   2767 H HB3  . LEU A 1 175 ? 20.74938  2.88787   10.83844  1.000 21.13811  ? 167 LEU A HB3  1 
ATOM   2768 H HG   . LEU A 1 175 ? 21.84505  4.31565   13.02536  1.000 21.95064  ? 167 LEU A HG   1 
ATOM   2769 H HD11 . LEU A 1 175 ? 19.92952  5.61981   13.04637  1.000 20.21905  ? 167 LEU A HD11 1 
ATOM   2770 H HD12 . LEU A 1 175 ? 20.72023  5.82981   11.68468  1.000 20.21905  ? 167 LEU A HD12 1 
ATOM   2771 H HD13 . LEU A 1 175 ? 19.42585  4.90949   11.71773  1.000 20.21905  ? 167 LEU A HD13 1 
ATOM   2772 H HD21 . LEU A 1 175 ? 19.98563  3.46967   14.17183  1.000 22.20389  ? 167 LEU A HD21 1 
ATOM   2773 H HD22 . LEU A 1 175 ? 19.63918  2.59363   12.89275  1.000 22.20389  ? 167 LEU A HD22 1 
ATOM   2774 H HD23 . LEU A 1 175 ? 20.98110  2.32537   13.69948  1.000 22.20389  ? 167 LEU A HD23 1 
ATOM   2775 N N    . TRP A 1 176 ? 23.90468  2.01528   9.37857   1.000 13.11501  ? 168 TRP A N    1 
ATOM   2776 C CA   . TRP A 1 176 ? 24.31995  1.43418   8.11258   1.000 13.47942  ? 168 TRP A CA   1 
ATOM   2777 C C    . TRP A 1 176 ? 25.77512  1.01275   8.21397   1.000 17.01048  ? 168 TRP A C    1 
ATOM   2778 O O    . TRP A 1 176 ? 26.59203  1.72601   8.79657   1.000 17.30470  ? 168 TRP A O    1 
ATOM   2779 C CB   . TRP A 1 176 ? 24.16255  2.42515   6.96682   1.000 15.52828  ? 168 TRP A CB   1 
ATOM   2780 C CG   . TRP A 1 176 ? 22.77104  2.93503   6.81413   1.000 15.78920  ? 168 TRP A CG   1 
ATOM   2781 C CD1  . TRP A 1 176 ? 22.30494  4.17199   7.15164   1.000 19.99320  ? 168 TRP A CD1  1 
ATOM   2782 C CD2  . TRP A 1 176 ? 21.65515  2.21859   6.27618   1.000 11.28062  ? 168 TRP A CD2  1 
ATOM   2783 N NE1  . TRP A 1 176 ? 20.96937  4.26366   6.86244   1.000 15.63159  ? 168 TRP A NE1  1 
ATOM   2784 C CE2  . TRP A 1 176 ? 20.54667  3.08094   6.32202   1.000 16.39289  ? 168 TRP A CE2  1 
ATOM   2785 C CE3  . TRP A 1 176 ? 21.49152  0.93949   5.74483   1.000 13.58783  ? 168 TRP A CE3  1 
ATOM   2786 C CZ2  . TRP A 1 176 ? 19.29214  2.69864   5.86950   1.000 13.93665  ? 168 TRP A CZ2  1 
ATOM   2787 C CZ3  . TRP A 1 176 ? 20.23697  0.56115   5.29387   1.000 16.39868  ? 168 TRP A CZ3  1 
ATOM   2788 C CH2  . TRP A 1 176 ? 19.15644  1.43539   5.37125   1.000 14.08894  ? 168 TRP A CH2  1 
ATOM   2789 H H    . TRP A 1 176 ? 24.38814  2.68435   9.61983   1.000 15.75504  ? 168 TRP A H    1 
ATOM   2790 H HA   . TRP A 1 176 ? 23.77424  0.65598   7.91893   1.000 16.19233  ? 168 TRP A HA   1 
ATOM   2791 H HB2  . TRP A 1 176 ? 24.74233  3.18585   7.12835   1.000 18.65096  ? 168 TRP A HB2  1 
ATOM   2792 H HB3  . TRP A 1 176 ? 24.41211  1.98797   6.13767   1.000 18.65096  ? 168 TRP A HB3  1 
ATOM   2793 H HD1  . TRP A 1 176 ? 22.81837  4.85256   7.52326   1.000 24.00887  ? 168 TRP A HD1  1 
ATOM   2794 H HE1  . TRP A 1 176 ? 20.47567  4.95448   6.99890   1.000 18.77493  ? 168 TRP A HE1  1 
ATOM   2795 H HE3  . TRP A 1 176 ? 22.21050  0.35179   5.69413   1.000 16.32241  ? 168 TRP A HE3  1 
ATOM   2796 H HZ2  . TRP A 1 176 ? 18.56919  3.28261   5.90447   1.000 16.74100  ? 168 TRP A HZ2  1 
ATOM   2797 H HZ3  . TRP A 1 176 ? 20.11530  -0.28806  4.93478   1.000 19.69544  ? 168 TRP A HZ3  1 
ATOM   2798 H HH2  . TRP A 1 176 ? 18.32143  1.15158   5.07610   1.000 16.92375  ? 168 TRP A HH2  1 
ATOM   2799 N N    . GLY A 1 177 ? 26.10162  -0.13594  7.62628   1.000 15.04549  ? 169 GLY A N    1 
ATOM   2800 C CA   . GLY A 1 177 ? 27.48644  -0.57430  7.59437   1.000 21.02502  ? 169 GLY A CA   1 
ATOM   2801 C C    . GLY A 1 177 ? 28.28630  -0.00020  6.45049   1.000 16.76610  ? 169 GLY A C    1 
ATOM   2802 O O    . GLY A 1 177 ? 29.52013  -0.02448  6.49421   1.000 18.48892  ? 169 GLY A O    1 
ATOM   2803 H H    . GLY A 1 177 ? 25.54569  -0.66997  7.24504   1.000 18.07161  ? 169 GLY A H    1 
ATOM   2804 H HA2  . GLY A 1 177 ? 27.91799  -0.31216  8.42259   1.000 25.24705  ? 169 GLY A HA2  1 
ATOM   2805 H HA3  . GLY A 1 177 ? 27.50814  -1.54114  7.51921   1.000 25.24705  ? 169 GLY A HA3  1 
ATOM   2806 N N    . TRP A 1 178 ? 27.60459  0.54906   5.45433   1.000 13.54723  ? 170 TRP A N    1 
ATOM   2807 C CA   . TRP A 1 178 ? 28.18784  1.04488   4.21848   1.000 17.67879  ? 170 TRP A CA   1 
ATOM   2808 C C    . TRP A 1 178 ? 27.14279  1.94186   3.57579   1.000 20.41345  ? 170 TRP A C    1 
ATOM   2809 O O    . TRP A 1 178 ? 25.95424  1.60718   3.56397   1.000 14.25020  ? 170 TRP A O    1 
ATOM   2810 C CB   . TRP A 1 178 ? 28.56964  -0.11031  3.29070   1.000 19.42394  ? 170 TRP A CB   1 
ATOM   2811 C CG   . TRP A 1 178 ? 29.06992  0.28803   1.94416   1.000 16.24707  ? 170 TRP A CG   1 
ATOM   2812 C CD1  . TRP A 1 178 ? 30.36186  0.59276   1.60236   1.000 24.91102  ? 170 TRP A CD1  1 
ATOM   2813 C CD2  . TRP A 1 178 ? 28.29753  0.40511   0.73587   1.000 15.74517  ? 170 TRP A CD2  1 
ATOM   2814 N NE1  . TRP A 1 178 ? 30.43389  0.89369   0.26518   1.000 20.03584  ? 170 TRP A NE1  1 
ATOM   2815 C CE2  . TRP A 1 178 ? 29.18450  0.78562   -0.28789  1.000 26.85550  ? 170 TRP A CE2  1 
ATOM   2816 C CE3  . TRP A 1 178 ? 26.94537  0.21549   0.42194   1.000 17.72817  ? 170 TRP A CE3  1 
ATOM   2817 C CZ2  . TRP A 1 178 ? 28.76486  0.99150   -1.59584  1.000 19.24968  ? 170 TRP A CZ2  1 
ATOM   2818 C CZ3  . TRP A 1 178 ? 26.53278  0.41305   -0.88400  1.000 21.32935  ? 170 TRP A CZ3  1 
ATOM   2819 C CH2  . TRP A 1 178 ? 27.43952  0.80059   -1.87358  1.000 21.64890  ? 170 TRP A CH2  1 
ATOM   2820 H H    . TRP A 1 178 ? 26.75094  0.65202   5.47145   1.000 16.27370  ? 170 TRP A H    1 
ATOM   2821 H HA   . TRP A 1 178 ? 28.99301  1.55930   4.38569   1.000 21.23157  ? 170 TRP A HA   1 
ATOM   2822 H HB2  . TRP A 1 178 ? 29.27095  -0.62633  3.71823   1.000 23.32574  ? 170 TRP A HB2  1 
ATOM   2823 H HB3  . TRP A 1 178 ? 27.78548  -0.66489  3.15493   1.000 23.32574  ? 170 TRP A HB3  1 
ATOM   2824 H HD1  . TRP A 1 178 ? 31.08297  0.59525   2.18964   1.000 29.91025  ? 170 TRP A HD1  1 
ATOM   2825 H HE1  . TRP A 1 178 ? 31.14904  1.11482   -0.15821  1.000 24.06003  ? 170 TRP A HE1  1 
ATOM   2826 H HE3  . TRP A 1 178 ? 26.33719  -0.03811  1.07821   1.000 21.29083  ? 170 TRP A HE3  1 
ATOM   2827 H HZ2  . TRP A 1 178 ? 29.36365  1.24988   -2.25885  1.000 23.11664  ? 170 TRP A HZ2  1 
ATOM   2828 H HZ3  . TRP A 1 178 ? 25.63870  0.28597   -1.10621  1.000 25.61224  ? 170 TRP A HZ3  1 
ATOM   2829 H HH2  . TRP A 1 178 ? 27.13445  0.93192   -2.74225  1.000 25.99571  ? 170 TRP A HH2  1 
ATOM   2830 N N    . GLN A 1 179 ? 27.58158  3.09359   3.08253   1.000 17.45636  ? 171 GLN A N    1 
ATOM   2831 C CA   . GLN A 1 179 ? 26.68128  4.00677   2.39403   1.000 14.21203  ? 171 GLN A CA   1 
ATOM   2832 C C    . GLN A 1 179 ? 27.49182  4.98665   1.56816   1.000 23.00866  ? 171 GLN A C    1 
ATOM   2833 O O    . GLN A 1 179 ? 28.58667  5.38749   1.96069   1.000 23.34104  ? 171 GLN A O    1 
ATOM   2834 C CB   . GLN A 1 179 ? 25.78822  4.77051   3.37639   1.000 18.10648  ? 171 GLN A CB   1 
ATOM   2835 C CG   . GLN A 1 179 ? 26.52416  5.75955   4.25292   1.000 21.25688  ? 171 GLN A CG   1 
ATOM   2836 C CD   . GLN A 1 179 ? 25.74443  6.10796   5.51995   1.000 33.22949  ? 171 GLN A CD   1 
ATOM   2837 O OE1  . GLN A 1 179 ? 26.06887  5.64545   6.61281   1.000 56.49950  ? 171 GLN A OE1  1 
ATOM   2838 N NE2  . GLN A 1 179 ? 24.71382  6.91901   5.37320   1.000 26.60128  ? 171 GLN A NE2  1 
ATOM   2839 H H    . GLN A 1 179 ? 28.39497  3.36812   3.13383   1.000 20.96466  ? 171 GLN A H    1 
ATOM   2840 H HA   . GLN A 1 179 ? 26.11731  3.49384   1.79425   1.000 17.07145  ? 171 GLN A HA   1 
ATOM   2841 H HB2  . GLN A 1 179 ? 25.12421  5.26456   2.87053   1.000 21.74480  ? 171 GLN A HB2  1 
ATOM   2842 H HB3  . GLN A 1 179 ? 25.35190  4.12993   3.95964   1.000 21.74480  ? 171 GLN A HB3  1 
ATOM   2843 H HG2  . GLN A 1 179 ? 27.37497  5.37669   4.51833   1.000 25.52528  ? 171 GLN A HG2  1 
ATOM   2844 H HG3  . GLN A 1 179 ? 26.67008  6.57853   3.75405   1.000 25.52528  ? 171 GLN A HG3  1 
ATOM   2845 H HE21 . GLN A 1 179 ? 24.51253  7.22187   4.59386   1.000 31.93856  ? 171 GLN A HE21 1 
ATOM   2846 H HE22 . GLN A 1 179 ? 24.24347  7.14470   6.05689   1.000 31.93856  ? 171 GLN A HE22 1 
ATOM   2847 N N    . GLY A 1 180 ? 26.92279  5.39279   0.43802   1.000 19.71590  ? 172 GLY A N    1 
ATOM   2848 C CA   . GLY A 1 180 ? 27.62045  6.26178   -0.49074  1.000 24.12270  ? 172 GLY A CA   1 
ATOM   2849 C C    . GLY A 1 180 ? 26.63957  6.98577   -1.37948  1.000 32.86385  ? 172 GLY A C    1 
ATOM   2850 O O    . GLY A 1 180 ? 25.46574  6.61675   -1.48142  1.000 19.99837  ? 172 GLY A O    1 
ATOM   2851 H H    . GLY A 1 180 ? 26.12909  5.17614   0.18763   1.000 23.67610  ? 172 GLY A H    1 
ATOM   2852 H HA2  . GLY A 1 180 ? 28.14051  6.91708   0.00019   1.000 28.96426  ? 172 GLY A HA2  1 
ATOM   2853 H HA3  . GLY A 1 180 ? 28.21752  5.73672   -1.04636  1.000 28.96426  ? 172 GLY A HA3  1 
ATOM   2854 N N    . HIS A 1 181 ? 27.13438  8.03971   -2.02353  1.000 21.58717  ? 173 HIS A N    1 
ATOM   2855 C CA   . HIS A 1 181 ? 26.32531  8.85658   -2.90963  1.000 20.61161  ? 173 HIS A CA   1 
ATOM   2856 C C    . HIS A 1 181 ? 27.15288  9.21898   -4.13157  1.000 24.89680  ? 173 HIS A C    1 
ATOM   2857 O O    . HIS A 1 181 ? 28.38359  9.27504   -4.07448  1.000 27.32000  ? 173 HIS A O    1 
ATOM   2858 C CB   . HIS A 1 181 ? 25.82931  10.11369  -2.20104  1.000 22.17646  ? 173 HIS A CB   1 
ATOM   2859 C CG   . HIS A 1 181 ? 25.10864  9.83598   -0.91774  1.000 25.54173  ? 173 HIS A CG   1 
ATOM   2860 N ND1  . HIS A 1 181 ? 23.73490  9.75093   -0.83811  1.000 20.23812  ? 173 HIS A ND1  1 
ATOM   2861 C CD2  . HIS A 1 181 ? 25.57108  9.63377   0.33835   1.000 30.30806  ? 173 HIS A CD2  1 
ATOM   2862 C CE1  . HIS A 1 181 ? 23.38314  9.49829   0.41009   1.000 26.58668  ? 173 HIS A CE1  1 
ATOM   2863 N NE2  . HIS A 1 181 ? 24.47855  9.41598   1.14343   1.000 28.72978  ? 173 HIS A NE2  1 
ATOM   2864 H H    . HIS A 1 181 ? 27.95062  8.30287   -1.95960  1.000 25.92163  ? 173 HIS A H    1 
ATOM   2865 H HA   . HIS A 1 181 ? 25.54843  8.36074   -3.21211  1.000 24.75095  ? 173 HIS A HA   1 
ATOM   2866 H HB2  . HIS A 1 181 ? 26.59124  10.67823  -1.99693  1.000 26.62877  ? 173 HIS A HB2  1 
ATOM   2867 H HB3  . HIS A 1 181 ? 25.21705  10.58268  -2.78933  1.000 26.62877  ? 173 HIS A HB3  1 
ATOM   2868 H HD2  . HIS A 1 181 ? 26.46157  9.64088   0.60645   1.000 36.38670  ? 173 HIS A HD2  1 
ATOM   2869 H HE1  . HIS A 1 181 ? 22.51221  9.39582   0.71973   1.000 31.92103  ? 173 HIS A HE1  1 
ATOM   2870 N N    . PHE A 1 182 ? 26.47023  9.44356   -5.24544  1.000 27.77259  ? 174 PHE A N    1 
ATOM   2871 C CA   . PHE A 1 182 ? 27.13252  9.87459   -6.46688  1.000 24.13599  ? 174 PHE A CA   1 
ATOM   2872 C C    . PHE A 1 182 ? 26.23645  10.86422  -7.19473  1.000 29.08278  ? 174 PHE A C    1 
ATOM   2873 O O    . PHE A 1 182 ? 25.01812  10.66439  -7.28308  1.000 27.49927  ? 174 PHE A O    1 
ATOM   2874 C CB   . PHE A 1 182 ? 27.47969  8.70206   -7.39045  1.000 28.36493  ? 174 PHE A CB   1 
ATOM   2875 C CG   . PHE A 1 182 ? 28.49736  9.05812   -8.43804  1.000 27.74937  ? 174 PHE A CG   1 
ATOM   2876 C CD1  . PHE A 1 182 ? 29.85134  9.03547   -8.14151  1.000 40.19675  ? 174 PHE A CD1  1 
ATOM   2877 C CD2  . PHE A 1 182 ? 28.09963  9.43458   -9.70833  1.000 44.04917  ? 174 PHE A CD2  1 
ATOM   2878 C CE1  . PHE A 1 182 ? 30.78803  9.37270   -9.09665  1.000 47.14004  ? 174 PHE A CE1  1 
ATOM   2879 C CE2  . PHE A 1 182 ? 29.03292  9.77560   -10.66778 1.000 50.82866  ? 174 PHE A CE2  1 
ATOM   2880 C CZ   . PHE A 1 182 ? 30.37581  9.74943   -10.35968 1.000 45.19357  ? 174 PHE A CZ   1 
ATOM   2881 H H    . PHE A 1 182 ? 25.61821  9.35271   -5.31895  1.000 33.34413  ? 174 PHE A H    1 
ATOM   2882 H HA   . PHE A 1 182 ? 27.96423  10.31768  -6.23704  1.000 28.98021  ? 174 PHE A HA   1 
ATOM   2883 H HB2  . PHE A 1 182 ? 27.84136  7.97753   -6.85645  1.000 34.05494  ? 174 PHE A HB2  1 
ATOM   2884 H HB3  . PHE A 1 182 ? 26.67365  8.40961   -7.84395  1.000 34.05494  ? 174 PHE A HB3  1 
ATOM   2885 H HD1  . PHE A 1 182 ? 30.13139  8.79022   -7.28926  1.000 48.25312  ? 174 PHE A HD1  1 
ATOM   2886 H HD2  . PHE A 1 182 ? 27.19403  9.45832   -9.91863  1.000 52.87603  ? 174 PHE A HD2  1 
ATOM   2887 H HE1  . PHE A 1 182 ? 31.69452  9.34639   -8.89051  1.000 56.58507  ? 174 PHE A HE1  1 
ATOM   2888 H HE2  . PHE A 1 182 ? 28.75545  10.02248  -11.52040 1.000 61.01142  ? 174 PHE A HE2  1 
ATOM   2889 H HZ   . PHE A 1 182 ? 31.00484  9.98561   -11.00268 1.000 54.24931  ? 174 PHE A HZ   1 
ATOM   2890 N N    . ASN A 1 183 ? 26.84691  11.93479  -7.71849  1.000 31.52156  ? 175 ASN A N    1 
ATOM   2891 C CA   . ASN A 1 183 ? 26.07465  13.02718  -8.29235  1.000 34.43022  ? 175 ASN A CA   1 
ATOM   2892 C C    . ASN A 1 183 ? 24.99954  13.36717  -7.27900  1.000 22.42828  ? 175 ASN A C    1 
ATOM   2893 O O    . ASN A 1 183 ? 25.23817  13.23578  -6.07506  1.000 27.31348  ? 175 ASN A O    1 
ATOM   2894 C CB   . ASN A 1 183 ? 25.51776  12.63897  -9.65594  1.000 37.93351  ? 175 ASN A CB   1 
ATOM   2895 C CG   . ASN A 1 183 ? 26.62867  12.40301  -10.67449 1.000 54.70559  ? 175 ASN A CG   1 
ATOM   2896 O OD1  . ASN A 1 183 ? 27.72521  12.96221  -10.56128 1.000 57.42923  ? 175 ASN A OD1  1 
ATOM   2897 N ND2  . ASN A 1 183 ? 26.35520  11.56437  -11.66406 1.000 40.04624  ? 175 ASN A ND2  1 
ATOM   2898 H H    . ASN A 1 183 ? 27.69922  12.04515  -7.75017  1.000 37.84289  ? 175 ASN A H    1 
ATOM   2899 H HA   . ASN A 1 183 ? 26.61121  13.81598  -8.46782  1.000 41.33329  ? 175 ASN A HA   1 
ATOM   2900 H HB2  . ASN A 1 183 ? 25.00452  11.82032  -9.57059  1.000 45.53724  ? 175 ASN A HB2  1 
ATOM   2901 H HB3  . ASN A 1 183 ? 24.95028  13.35354  -9.98494  1.000 45.53724  ? 175 ASN A HB3  1 
ATOM   2902 H HD21 . ASN A 1 183 ? 25.58395  11.18624  -11.70651 1.000 48.07251  ? 175 ASN A HD21 1 
ATOM   2903 H HD22 . ASN A 1 183 ? 26.94904  11.39843  -12.26358 1.000 48.07251  ? 175 ASN A HD22 1 
ATOM   2904 N N    . GLU A 1 184 ? 23.81979  13.76934  -7.73294  1.000 23.80427  ? 176 GLU A N    1 
ATOM   2905 C CA   . GLU A 1 184 ? 22.75148  14.16100  -6.82482  1.000 16.95305  ? 176 GLU A CA   1 
ATOM   2906 C C    . GLU A 1 184 ? 21.60973  13.15336  -6.73612  1.000 29.78334  ? 176 GLU A C    1 
ATOM   2907 O O    . GLU A 1 184 ? 20.69751  13.34024  -5.92178  1.000 25.25615  ? 176 GLU A O    1 
ATOM   2908 C CB   . GLU A 1 184 ? 22.18226  15.52208  -7.24170  1.000 27.99911  ? 176 GLU A CB   1 
ATOM   2909 C CG   . GLU A 1 184 ? 23.25058  16.57744  -7.48864  1.000 58.48907  ? 176 GLU A CG   1 
ATOM   2910 C CD   . GLU A 1 184 ? 22.68151  17.88367  -8.01360  1.000 64.92002  ? 176 GLU A CD   1 
ATOM   2911 O OE1  . GLU A 1 184 ? 23.19745  18.38806  -9.03542  1.000 71.30103  ? 176 GLU A OE1  1 
ATOM   2912 O OE2  . GLU A 1 184 ? 21.72168  18.40424  -7.40238  1.000 54.32749  ? 176 GLU A OE2  1 
ATOM   2913 H H    . GLU A 1 184 ? 23.61312  13.82411  -8.56594  1.000 28.58214  ? 176 GLU A H    1 
ATOM   2914 H HA   . GLU A 1 184 ? 23.12789  14.24717  -5.93499  1.000 20.36068  ? 176 GLU A HA   1 
ATOM   2915 H HB2  . GLU A 1 184 ? 21.67803  15.41186  -8.06298  1.000 33.61595  ? 176 GLU A HB2  1 
ATOM   2916 H HB3  . GLU A 1 184 ? 21.60088  15.84712  -6.53655  1.000 33.61595  ? 176 GLU A HB3  1 
ATOM   2917 H HG2  . GLU A 1 184 ? 23.70817  16.76439  -6.65403  1.000 70.20391  ? 176 GLU A HG2  1 
ATOM   2918 H HG3  . GLU A 1 184 ? 23.88101  16.24071  -8.14444  1.000 70.20391  ? 176 GLU A HG3  1 
ATOM   2919 N N    . ASP A 1 185 ? 21.63219  12.09372  -7.53380  1.000 25.62586  ? 177 ASP A N    1 
ATOM   2920 C CA   . ASP A 1 185 ? 20.48922  11.19489  -7.62815  1.000 27.48839  ? 177 ASP A CA   1 
ATOM   2921 C C    . ASP A 1 185 ? 20.85218  9.73787   -7.36881  1.000 21.27240  ? 177 ASP A C    1 
ATOM   2922 O O    . ASP A 1 185 ? 20.01705  8.84989   -7.61087  1.000 21.46869  ? 177 ASP A O    1 
ATOM   2923 C CB   . ASP A 1 185 ? 19.83129  11.33523  -9.00850  1.000 25.63180  ? 177 ASP A CB   1 
ATOM   2924 C CG   . ASP A 1 185 ? 20.78258  11.03449  -10.14110 1.000 33.60480  ? 177 ASP A CG   1 
ATOM   2925 O OD1  . ASP A 1 185 ? 22.00812  11.01470  -9.90446  1.000 36.56650  ? 177 ASP A OD1  1 
ATOM   2926 O OD2  . ASP A 1 185 ? 20.31046  10.80649  -11.27788 1.000 38.18957  ? 177 ASP A OD2  1 
ATOM   2927 H H    . ASP A 1 185 ? 22.29824  11.87326  -8.03117  1.000 30.76806  ? 177 ASP A H    1 
ATOM   2928 H HA   . ASP A 1 185 ? 19.83998  11.44505  -6.95226  1.000 33.00309  ? 177 ASP A HA   1 
ATOM   2929 H HB2  . ASP A 1 185 ? 19.08750  10.71551  -9.06877  1.000 30.77518  ? 177 ASP A HB2  1 
ATOM   2930 H HB3  . ASP A 1 185 ? 19.51424  12.24555  -9.11661  1.000 30.77518  ? 177 ASP A HB3  1 
ATOM   2931 N N    . VAL A 1 186 ? 22.06243  9.46072   -6.89243  1.000 18.93714  ? 178 VAL A N    1 
ATOM   2932 C CA   . VAL A 1 186 ? 22.50373  8.10105   -6.60970  1.000 19.97973  ? 178 VAL A CA   1 
ATOM   2933 C C    . VAL A 1 186 ? 22.78344  8.01029   -5.11737  1.000 26.28864  ? 178 VAL A C    1 
ATOM   2934 O O    . VAL A 1 186 ? 23.62875  8.74482   -4.58974  1.000 19.04305  ? 178 VAL A O    1 
ATOM   2935 C CB   . VAL A 1 186 ? 23.74125  7.70517   -7.42883  1.000 16.99622  ? 178 VAL A CB   1 
ATOM   2936 C CG1  . VAL A 1 186 ? 24.09090  6.24759   -7.18083  1.000 22.31484  ? 178 VAL A CG1  1 
ATOM   2937 C CG2  . VAL A 1 186 ? 23.52272  7.97518   -8.91819  1.000 19.79425  ? 178 VAL A CG2  1 
ATOM   2938 H H    . VAL A 1 186 ? 22.65734  10.05784  -6.72179  1.000 22.74159  ? 178 VAL A H    1 
ATOM   2939 H HA   . VAL A 1 186 ? 21.79135  7.48111   -6.83126  1.000 23.99270  ? 178 VAL A HA   1 
ATOM   2940 H HB   . VAL A 1 186 ? 24.49289  8.24849   -7.14469  1.000 20.41248  ? 178 VAL A HB   1 
ATOM   2941 H HG11 . VAL A 1 186 ? 24.83417  5.99944   -7.75255  1.000 26.79482  ? 178 VAL A HG11 1 
ATOM   2942 H HG12 . VAL A 1 186 ? 24.33837  6.13624   -6.24956  1.000 26.79482  ? 178 VAL A HG12 1 
ATOM   2943 H HG13 . VAL A 1 186 ? 23.31819  5.69819   -7.38572  1.000 26.79482  ? 178 VAL A HG13 1 
ATOM   2944 H HG21 . VAL A 1 186 ? 24.30146  7.67329   -9.41146  1.000 23.77013  ? 178 VAL A HG21 1 
ATOM   2945 H HG22 . VAL A 1 186 ? 22.73562  7.49194   -9.21459  1.000 23.77013  ? 178 VAL A HG22 1 
ATOM   2946 H HG23 . VAL A 1 186 ? 23.39570  8.92759   -9.05116  1.000 23.77013  ? 178 VAL A HG23 1 
ATOM   2947 N N    . HIS A 1 187 ? 22.07419  7.11381   -4.43868  1.000 16.60274  ? 179 HIS A N    1 
ATOM   2948 C CA   . HIS A 1 187 ? 22.13008  7.01759   -2.98259  1.000 11.73579  ? 179 HIS A CA   1 
ATOM   2949 C C    . HIS A 1 187 ? 22.05238  5.55204   -2.59974  1.000 18.34483  ? 179 HIS A C    1 
ATOM   2950 O O    . HIS A 1 187 ? 21.00347  4.91943   -2.76621  1.000 16.03431  ? 179 HIS A O    1 
ATOM   2951 C CB   . HIS A 1 187 ? 20.99265  7.80039   -2.33607  1.000 13.70421  ? 179 HIS A CB   1 
ATOM   2952 C CG   . HIS A 1 187 ? 20.80672  9.17135   -2.90567  1.000 20.62067  ? 179 HIS A CG   1 
ATOM   2953 N ND1  . HIS A 1 187 ? 21.54368  10.26237  -2.48826  1.000 17.77919  ? 179 HIS A ND1  1 
ATOM   2954 C CD2  . HIS A 1 187 ? 19.98115  9.62424   -3.87758  1.000 24.11783  ? 179 HIS A CD2  1 
ATOM   2955 C CE1  . HIS A 1 187 ? 21.17062  11.32758  -3.17461  1.000 24.55515  ? 179 HIS A CE1  1 
ATOM   2956 N NE2  . HIS A 1 187 ? 20.22317  10.96814  -4.02366  1.000 26.23794  ? 179 HIS A NE2  1 
ATOM   2957 H H    . HIS A 1 187 ? 21.54566  6.54202   -4.80381  1.000 19.94031  ? 179 HIS A H    1 
ATOM   2958 H HA   . HIS A 1 187 ? 22.97543  7.37555   -2.66931  1.000 14.09997  ? 179 HIS A HA   1 
ATOM   2959 H HB2  . HIS A 1 187 ? 20.16480  7.31140   -2.46435  1.000 16.46207  ? 179 HIS A HB2  1 
ATOM   2960 H HB3  . HIS A 1 187 ? 21.17828  7.89572   -1.38878  1.000 16.46207  ? 179 HIS A HB3  1 
ATOM   2961 H HD2  . HIS A 1 187 ? 19.36472  9.11942   -4.35725  1.000 28.95842  ? 179 HIS A HD2  1 
ATOM   2962 H HE1  . HIS A 1 187 ? 21.51612  12.18549  -3.07703  1.000 29.48320  ? 179 HIS A HE1  1 
ATOM   2963 N N    . TYR A 1 188 ? 23.15892  5.02146   -2.09918  1.000 12.68201  ? 180 TYR A N    1 
ATOM   2964 C CA   . TYR A 1 188 ? 23.28216  3.61573   -1.75234  1.000 12.33805  ? 180 TYR A CA   1 
ATOM   2965 C C    . TYR A 1 188 ? 23.48617  3.45535   -0.25376  1.000 13.83714  ? 180 TYR A C    1 
ATOM   2966 O O    . TYR A 1 188 ? 24.26945  4.18886   0.36061   1.000 15.19375  ? 180 TYR A O    1 
ATOM   2967 C CB   . TYR A 1 188 ? 24.45826  2.96844   -2.47793  1.000 12.60964  ? 180 TYR A CB   1 
ATOM   2968 C CG   . TYR A 1 188 ? 24.13862  2.45887   -3.87010  1.000 11.60597  ? 180 TYR A CG   1 
ATOM   2969 C CD1  . TYR A 1 188 ? 23.83590  3.33578   -4.88638  1.000 15.40073  ? 180 TYR A CD1  1 
ATOM   2970 C CD2  . TYR A 1 188 ? 24.14654  1.10186   -4.15436  1.000 13.32199  ? 180 TYR A CD2  1 
ATOM   2971 C CE1  . TYR A 1 188 ? 23.55848  2.88156   -6.15656  1.000 17.97470  ? 180 TYR A CE1  1 
ATOM   2972 C CE2  . TYR A 1 188 ? 23.85863  0.63714   -5.41994  1.000 12.11873  ? 180 TYR A CE2  1 
ATOM   2973 C CZ   . TYR A 1 188 ? 23.57594  1.52658   -6.40929  1.000 12.91964  ? 180 TYR A CZ   1 
ATOM   2974 O OH   . TYR A 1 188 ? 23.28600  1.07279   -7.67641  1.000 18.26178  ? 180 TYR A OH   1 
ATOM   2975 H H    . TYR A 1 188 ? 23.87541  5.47200   -1.94672  1.000 15.23544  ? 180 TYR A H    1 
ATOM   2976 H HA   . TYR A 1 188 ? 22.46361  3.16187   -2.00706  1.000 14.82269  ? 180 TYR A HA   1 
ATOM   2977 H HB2  . TYR A 1 188 ? 25.16757  3.62467   -2.56246  1.000 15.14859  ? 180 TYR A HB2  1 
ATOM   2978 H HB3  . TYR A 1 188 ? 24.76619  2.21276   -1.95350  1.000 15.14859  ? 180 TYR A HB3  1 
ATOM   2979 H HD1  . TYR A 1 188 ? 23.81836  4.24927   -4.71283  1.000 18.49789  ? 180 TYR A HD1  1 
ATOM   2980 H HD2  . TYR A 1 188 ? 24.34955  0.49475   -3.47975  1.000 16.00341  ? 180 TYR A HD2  1 
ATOM   2981 H HE1  . TYR A 1 188 ? 23.36118  3.48345   -6.83752  1.000 21.58666  ? 180 TYR A HE1  1 
ATOM   2982 H HE2  . TYR A 1 188 ? 23.85771  -0.27612  -5.59557  1.000 14.55949  ? 180 TYR A HE2  1 
ATOM   2983 H HH   . TYR A 1 188 ? 23.15388  1.72322   -8.19128  1.000 21.93115  ? 180 TYR A HH   1 
ATOM   2984 N N    . TYR A 1 189 ? 22.77178  2.48961   0.32437   1.000 11.52944  ? 181 TYR A N    1 
ATOM   2985 C CA   . TYR A 1 189 ? 22.86331  2.12478   1.73056   1.000 11.39490  ? 181 TYR A CA   1 
ATOM   2986 C C    . TYR A 1 189 ? 22.87603  0.60807   1.85217   1.000 14.36611  ? 181 TYR A C    1 
ATOM   2987 O O    . TYR A 1 189 ? 22.15361  -0.08117  1.12625   1.000 13.10870  ? 181 TYR A O    1 
ATOM   2988 C CB   . TYR A 1 189 ? 21.67620  2.67055   2.54247   1.000 10.92453  ? 181 TYR A CB   1 
ATOM   2989 C CG   . TYR A 1 189 ? 21.48729  4.16383   2.45910   1.000 11.24590  ? 181 TYR A CG   1 
ATOM   2990 C CD1  . TYR A 1 189 ? 21.97995  4.99138   3.44780   1.000 12.63960  ? 181 TYR A CD1  1 
ATOM   2991 C CD2  . TYR A 1 189 ? 20.85337  4.75592   1.36743   1.000 10.50240  ? 181 TYR A CD2  1 
ATOM   2992 C CE1  . TYR A 1 189 ? 21.82981  6.36706   3.36741   1.000 16.93670  ? 181 TYR A CE1  1 
ATOM   2993 C CE2  . TYR A 1 189 ? 20.69601  6.12166   1.29308   1.000 13.77846  ? 181 TYR A CE2  1 
ATOM   2994 C CZ   . TYR A 1 189 ? 21.18133  6.91808   2.29815   1.000 17.26408  ? 181 TYR A CZ   1 
ATOM   2995 O OH   . TYR A 1 189 ? 21.02073  8.28111   2.21015   1.000 18.55827  ? 181 TYR A OH   1 
ATOM   2996 H H    . TYR A 1 189 ? 22.19944  2.00933   -0.10150  1.000 13.85235  ? 181 TYR A H    1 
ATOM   2997 H HA   . TYR A 1 189 ? 23.68561  2.48650   2.09644   1.000 13.69091  ? 181 TYR A HA   1 
ATOM   2998 H HB2  . TYR A 1 189 ? 20.86283  2.25490   2.21603   1.000 13.12646  ? 181 TYR A HB2  1 
ATOM   2999 H HB3  . TYR A 1 189 ? 21.81221  2.44535   3.47611   1.000 13.12646  ? 181 TYR A HB3  1 
ATOM   3000 H HD1  . TYR A 1 189 ? 22.41919  4.62048   4.17883   1.000 15.18455  ? 181 TYR A HD1  1 
ATOM   3001 H HD2  . TYR A 1 189 ? 20.53184  4.21993   0.67879   1.000 12.61991  ? 181 TYR A HD2  1 
ATOM   3002 H HE1  . TYR A 1 189 ? 22.16937  6.91335   4.03910   1.000 20.34106  ? 181 TYR A HE1  1 
ATOM   3003 H HE2  . TYR A 1 189 ? 20.26220  6.50254   0.56394   1.000 16.55118  ? 181 TYR A HE2  1 
ATOM   3004 H HH   . TYR A 1 189 ? 20.59101  8.47548   1.51505   1.000 22.28694  ? 181 TYR A HH   1 
ATOM   3005 N N    . ALA A 1 190 ? 23.66599  0.09109   2.79288   1.000 10.33977  ? 182 ALA A N    1 
ATOM   3006 C CA   . ALA A 1 190 ? 23.66915  -1.33316  3.09725   1.000 10.27940  ? 182 ALA A CA   1 
ATOM   3007 C C    . ALA A 1 190 ? 23.73279  -1.55010  4.60023   1.000 13.50015  ? 182 ALA A C    1 
ATOM   3008 O O    . ALA A 1 190 ? 24.47412  -0.86058  5.30660   1.000 13.44406  ? 182 ALA A O    1 
ATOM   3009 C CB   . ALA A 1 190 ? 24.84206  -2.03763  2.42863   1.000 12.67608  ? 182 ALA A CB   1 
ATOM   3010 H H    . ALA A 1 190 ? 24.21274  0.55163   3.27097   1.000 12.42474  ? 182 ALA A H    1 
ATOM   3011 H HA   . ALA A 1 190 ? 22.84218  -1.72571  2.77641   1.000 12.35231  ? 182 ALA A HA   1 
ATOM   3012 H HB1  . ALA A 1 190 ? 24.80864  -2.98235  2.64608   1.000 15.22832  ? 182 ALA A HB1  1 
ATOM   3013 H HB2  . ALA A 1 190 ? 24.77729  -1.91674  1.46837   1.000 15.22832  ? 182 ALA A HB2  1 
ATOM   3014 H HB3  . ALA A 1 190 ? 25.66996  -1.65206  2.75546   1.000 15.22832  ? 182 ALA A HB3  1 
ATOM   3015 N N    . LEU A 1 191 ? 22.93829  -2.50073  5.09270   1.000 10.22869  ? 183 LEU A N    1 
ATOM   3016 C CA   . LEU A 1 191 ? 22.86548  -2.70843  6.53748   1.000 10.19577  ? 183 LEU A CA   1 
ATOM   3017 C C    . LEU A 1 191 ? 24.19178  -3.22122  7.09918   1.000 11.86725  ? 183 LEU A C    1 
ATOM   3018 O O    . LEU A 1 191 ? 24.68242  -2.71992  8.12088   1.000 16.12400  ? 183 LEU A O    1 
ATOM   3019 C CB   . LEU A 1 191 ? 21.73493  -3.68320  6.88073   1.000 13.59673  ? 183 LEU A CB   1 
ATOM   3020 C CG   . LEU A 1 191 ? 20.32852  -3.16874  6.57299   1.000 15.61505  ? 183 LEU A CG   1 
ATOM   3021 C CD1  . LEU A 1 191 ? 19.29128  -4.25863  6.77143   1.000 15.08762  ? 183 LEU A CD1  1 
ATOM   3022 C CD2  . LEU A 1 191 ? 19.99080  -1.97217  7.45414   1.000 14.14153  ? 183 LEU A CD2  1 
ATOM   3023 H H    . LEU A 1 191 ? 22.44383  -3.02559  4.62405   1.000 12.29145  ? 183 LEU A H    1 
ATOM   3024 H HA   . LEU A 1 191 ? 22.66926  -1.85470  6.95408   1.000 12.25195  ? 183 LEU A HA   1 
ATOM   3025 H HB2  . LEU A 1 191 ? 21.86634  -4.49768  6.37059   1.000 16.33309  ? 183 LEU A HB2  1 
ATOM   3026 H HB3  . LEU A 1 191 ? 21.77408  -3.87662  7.83044   1.000 16.33309  ? 183 LEU A HB3  1 
ATOM   3027 H HG   . LEU A 1 191 ? 20.30387  -2.89086  5.64397   1.000 18.75508  ? 183 LEU A HG   1 
ATOM   3028 H HD11 . LEU A 1 191 ? 18.41825  -3.91140  6.53028   1.000 18.12217  ? 183 LEU A HD11 1 
ATOM   3029 H HD12 . LEU A 1 191 ? 19.51470  -5.01403  6.20544   1.000 18.12217  ? 183 LEU A HD12 1 
ATOM   3030 H HD13 . LEU A 1 191 ? 19.29337  -4.53083  7.70245   1.000 18.12217  ? 183 LEU A HD13 1 
ATOM   3031 H HD21 . LEU A 1 191 ? 19.09753  -1.66242  7.23731   1.000 16.98686  ? 183 LEU A HD21 1 
ATOM   3032 H HD22 . LEU A 1 191 ? 20.02990  -2.24402  8.38445   1.000 16.98686  ? 183 LEU A HD22 1 
ATOM   3033 H HD23 . LEU A 1 191 ? 20.63502  -1.26617  7.28848   1.000 16.98686  ? 183 LEU A HD23 1 
ATOM   3034 N N    . ALA A 1 192 ? 24.77808  -4.23329  6.46522   1.000 16.16698  ? 184 ALA A N    1 
ATOM   3035 C CA   . ALA A 1 192 ? 25.97706  -4.84898  7.02259   1.000 15.47890  ? 184 ALA A CA   1 
ATOM   3036 C C    . ALA A 1 192 ? 26.92434  -5.31351  5.92456   1.000 22.15083  ? 184 ALA A C    1 
ATOM   3037 O O    . ALA A 1 192 ? 26.47919  -5.70452  4.84083   1.000 16.42516  ? 184 ALA A O    1 
ATOM   3038 C CB   . ALA A 1 192 ? 25.62018  -6.04097  7.91959   1.000 18.66359  ? 184 ALA A CB   1 
ATOM   3039 H H    . ALA A 1 192 ? 24.50451  -4.57403  5.72450   1.000 19.41740  ? 184 ALA A H    1 
ATOM   3040 H HA   . ALA A 1 192 ? 26.44753  -4.17192  7.53363   1.000 18.59171  ? 184 ALA A HA   1 
ATOM   3041 H HB1  . ALA A 1 192 ? 26.43867  -6.45306  8.23764   1.000 22.41333  ? 184 ALA A HB1  1 
ATOM   3042 H HB2  . ALA A 1 192 ? 25.09538  -5.72444  8.67145   1.000 22.41333  ? 184 ALA A HB2  1 
ATOM   3043 H HB3  . ALA A 1 192 ? 25.10607  -6.68164  7.40371   1.000 22.41333  ? 184 ALA A HB3  1 
ATOM   3044 N N    . PRO A 1 193 ? 28.22769  -5.29822  6.18470   1.000 19.00610  ? 185 PRO A N    1 
ATOM   3045 C CA   . PRO A 1 193 ? 29.16789  -5.91106  5.23787   1.000 17.66905  ? 185 PRO A CA   1 
ATOM   3046 C C    . PRO A 1 193 ? 29.05102  -7.42828  5.26190   1.000 17.85513  ? 185 PRO A C    1 
ATOM   3047 O O    . PRO A 1 193 ? 28.58343  -8.03368  6.22955   1.000 21.39686  ? 185 PRO A O    1 
ATOM   3048 C CB   . PRO A 1 193 ? 30.54753  -5.45025  5.72810   1.000 19.66900  ? 185 PRO A CB   1 
ATOM   3049 C CG   . PRO A 1 193 ? 30.29330  -4.41655  6.79734   1.000 30.24401  ? 185 PRO A CG   1 
ATOM   3050 C CD   . PRO A 1 193 ? 28.90777  -4.70023  7.34595   1.000 20.95419  ? 185 PRO A CD   1 
ATOM   3051 H HA   . PRO A 1 193 ? 29.02344  -5.57656  4.33890   1.000 21.21989  ? 185 PRO A HA   1 
ATOM   3052 H HB2  . PRO A 1 193 ? 31.03246  -6.20735  6.09218   1.000 23.61982  ? 185 PRO A HB2  1 
ATOM   3053 H HB3  . PRO A 1 193 ? 31.04249  -5.06366  4.98888   1.000 23.61982  ? 185 PRO A HB3  1 
ATOM   3054 H HG2  . PRO A 1 193 ? 30.96106  -4.50051  7.49587   1.000 36.30984  ? 185 PRO A HG2  1 
ATOM   3055 H HG3  . PRO A 1 193 ? 30.33112  -3.52929  6.40715   1.000 36.30984  ? 185 PRO A HG3  1 
ATOM   3056 H HD2  . PRO A 1 193 ? 28.94692  -5.32460  8.08725   1.000 25.16205  ? 185 PRO A HD2  1 
ATOM   3057 H HD3  . PRO A 1 193 ? 28.46825  -3.88163  7.62452   1.000 25.16205  ? 185 PRO A HD3  1 
ATOM   3058 N N    . PHE A 1 194 ? 29.47998  -8.04503  4.16071   1.000 22.75774  ? 186 PHE A N    1 
ATOM   3059 C CA   . PHE A 1 194 ? 29.34136  -9.48543  3.99062   1.000 17.81857  ? 186 PHE A CA   1 
ATOM   3060 C C    . PHE A 1 194 ? 30.53204  -10.02400 3.21448   1.000 13.32244  ? 186 PHE A C    1 
ATOM   3061 O O    . PHE A 1 194 ? 30.96718  -9.41548  2.23516   1.000 19.48208  ? 186 PHE A O    1 
ATOM   3062 C CB   . PHE A 1 194 ? 28.04339  -9.82495  3.24533   1.000 18.60633  ? 186 PHE A CB   1 
ATOM   3063 C CG   . PHE A 1 194 ? 27.83938  -11.29495 3.00722   1.000 19.66446  ? 186 PHE A CG   1 
ATOM   3064 C CD1  . PHE A 1 194 ? 27.34954  -12.11030 4.01147   1.000 22.83194  ? 186 PHE A CD1  1 
ATOM   3065 C CD2  . PHE A 1 194 ? 28.14315  -11.85777 1.77726   1.000 26.22623  ? 186 PHE A CD2  1 
ATOM   3066 C CE1  . PHE A 1 194 ? 27.16387  -13.46662 3.79944   1.000 29.92791  ? 186 PHE A CE1  1 
ATOM   3067 C CE2  . PHE A 1 194 ? 27.95996  -13.21812 1.55744   1.000 24.20014  ? 186 PHE A CE2  1 
ATOM   3068 C CZ   . PHE A 1 194 ? 27.46560  -14.01685 2.57684   1.000 25.52614  ? 186 PHE A CZ   1 
ATOM   3069 H H    . PHE A 1 194 ? 29.85565  -7.64737  3.49713   1.000 27.32631  ? 186 PHE A H    1 
ATOM   3070 H HA   . PHE A 1 194 ? 29.33131  -9.91257  4.86146   1.000 21.39931  ? 186 PHE A HA   1 
ATOM   3071 H HB2  . PHE A 1 194 ? 27.29199  -9.50406  3.76812   1.000 22.34461  ? 186 PHE A HB2  1 
ATOM   3072 H HB3  . PHE A 1 194 ? 28.05769  -9.38559  2.38065   1.000 22.34461  ? 186 PHE A HB3  1 
ATOM   3073 H HD1  . PHE A 1 194 ? 27.14203  -11.74297 4.84027   1.000 27.41535  ? 186 PHE A HD1  1 
ATOM   3074 H HD2  . PHE A 1 194 ? 28.47236  -11.32055 1.09321   1.000 31.48849  ? 186 PHE A HD2  1 
ATOM   3075 H HE1  . PHE A 1 194 ? 26.83544  -14.00414 4.48362   1.000 35.93052  ? 186 PHE A HE1  1 
ATOM   3076 H HE2  . PHE A 1 194 ? 28.16795  -13.59032 0.73094   1.000 29.05719  ? 186 PHE A HE2  1 
ATOM   3077 H HZ   . PHE A 1 194 ? 27.33788  -14.92676 2.43311   1.000 30.64840  ? 186 PHE A HZ   1 
ATOM   3078 N N    . SER A 1 195 ? 31.03703  -11.17555 3.64855   1.000 23.21114  ? 187 SER A N    1 
ATOM   3079 C CA   . SER A 1 195 ? 32.07470  -11.88327 2.91407   1.000 25.24378  ? 187 SER A CA   1 
ATOM   3080 C C    . SER A 1 195 ? 31.86149  -13.37779 3.11271   1.000 17.81028  ? 187 SER A C    1 
ATOM   3081 O O    . SER A 1 195 ? 31.54743  -13.82822 4.21962   1.000 26.56640  ? 187 SER A O    1 
ATOM   3082 C CB   . SER A 1 195 ? 33.47620  -11.46951 3.37823   1.000 32.45511  ? 187 SER A CB   1 
ATOM   3083 O OG   . SER A 1 195 ? 33.76209  -12.04238 4.63497   1.000 38.36661  ? 187 SER A OG   1 
ATOM   3084 H H    . SER A 1 195 ? 30.79142  -11.56916 4.37267   1.000 27.87039  ? 187 SER A H    1 
ATOM   3085 H HA   . SER A 1 195 ? 32.00932  -11.68436 1.96693   1.000 30.30956  ? 187 SER A HA   1 
ATOM   3086 H HB2  . SER A 1 195 ? 34.12981  -11.77844 2.73151   1.000 38.96315  ? 187 SER A HB2  1 
ATOM   3087 H HB3  . SER A 1 195 ? 33.51442  -10.50314 3.45283   1.000 38.96315  ? 187 SER A HB3  1 
ATOM   3088 H HG   . SER A 1 195 ? 34.54058  -11.83655 4.87413   1.000 46.05696  ? 187 SER A HG   1 
ATOM   3089 N N    . THR A 1 196 ? 32.04079  -14.14249 2.03879   1.000 23.03573  ? 188 THR A N    1 
ATOM   3090 C CA   . THR A 1 196 ? 31.89943  -15.59044 2.09249   1.000 23.03997  ? 188 THR A CA   1 
ATOM   3091 C C    . THR A 1 196 ? 33.05168  -16.23920 1.33770   1.000 22.39030  ? 188 THR A C    1 
ATOM   3092 O O    . THR A 1 196 ? 33.87074  -15.56531 0.69916   1.000 22.90206  ? 188 THR A O    1 
ATOM   3093 C CB   . THR A 1 196 ? 30.55486  -16.05591 1.50791   1.000 25.58482  ? 188 THR A CB   1 
ATOM   3094 O OG1  . THR A 1 196 ? 30.37897  -17.45424 1.76811   1.000 41.90336  ? 188 THR A OG1  1 
ATOM   3095 C CG2  . THR A 1 196 ? 30.49539  -15.79333 0.01817   1.000 28.64659  ? 188 THR A CG2  1 
ATOM   3096 H H    . THR A 1 196 ? 32.24702  -13.84003 1.26060   1.000 27.65990  ? 188 THR A H    1 
ATOM   3097 H HA   . THR A 1 196 ? 31.93928  -15.87528 3.01887   1.000 27.66499  ? 188 THR A HA   1 
ATOM   3098 H HB   . THR A 1 196 ? 29.83097  -15.56123 1.92284   1.000 30.71880  ? 188 THR A HB   1 
ATOM   3099 H HG1  . THR A 1 196 ? 29.63170  -17.70820 1.48053   1.000 50.30105  ? 188 THR A HG1  1 
ATOM   3100 H HG21 . THR A 1 196 ? 29.60133  -15.96943 -0.31431  1.000 34.39293  ? 188 THR A HG21 1 
ATOM   3101 H HG22 . THR A 1 196 ? 30.72285  -14.86834 -0.16500  1.000 34.39293  ? 188 THR A HG22 1 
ATOM   3102 H HG23 . THR A 1 196 ? 31.12288  -16.36959 -0.44558  1.000 34.39293  ? 188 THR A HG23 1 
ATOM   3103 N N    . TYR A 1 197 ? 33.10868  -17.57219 1.42164   1.000 21.00716  ? 189 TYR A N    1 
ATOM   3104 C CA   . TYR A 1 197 ? 34.15163  -18.35211 0.76226   1.000 19.93665  ? 189 TYR A CA   1 
ATOM   3105 C C    . TYR A 1 197 ? 33.57003  -19.42452 -0.15869  1.000 20.18055  ? 189 TYR A C    1 
ATOM   3106 O O    . TYR A 1 197 ? 34.24429  -20.41724 -0.46036  1.000 21.31152  ? 189 TYR A O    1 
ATOM   3107 C CB   . TYR A 1 197 ? 35.08057  -18.98104 1.80741   1.000 20.06674  ? 189 TYR A CB   1 
ATOM   3108 C CG   . TYR A 1 197 ? 34.35426  -19.73890 2.90651   1.000 19.87240  ? 189 TYR A CG   1 
ATOM   3109 C CD1  . TYR A 1 197 ? 33.89744  -19.09279 4.05215   1.000 30.93462  ? 189 TYR A CD1  1 
ATOM   3110 C CD2  . TYR A 1 197 ? 34.12182  -21.10530 2.79416   1.000 25.29412  ? 189 TYR A CD2  1 
ATOM   3111 C CE1  . TYR A 1 197 ? 33.22467  -19.79450 5.04602   1.000 26.32992  ? 189 TYR A CE1  1 
ATOM   3112 C CE2  . TYR A 1 197 ? 33.45049  -21.80873 3.77977   1.000 29.74631  ? 189 TYR A CE2  1 
ATOM   3113 C CZ   . TYR A 1 197 ? 33.00658  -21.15329 4.90081   1.000 41.31391  ? 189 TYR A CZ   1 
ATOM   3114 O OH   . TYR A 1 197 ? 32.35010  -21.87042 5.87765   1.000 42.85543  ? 189 TYR A OH   1 
ATOM   3115 H H    . TYR A 1 197 ? 32.54529  -18.05047 1.86147   1.000 25.22561  ? 189 TYR A H    1 
ATOM   3116 H HA   . TYR A 1 197 ? 34.68342  -17.75831 0.20954   1.000 23.94100  ? 189 TYR A HA   1 
ATOM   3117 H HB2  . TYR A 1 197 ? 35.67298  -19.60578 1.36059   1.000 24.09711  ? 189 TYR A HB2  1 
ATOM   3118 H HB3  . TYR A 1 197 ? 35.59768  -18.27614 2.22765   1.000 24.09711  ? 189 TYR A HB3  1 
ATOM   3119 H HD1  . TYR A 1 197 ? 34.04424  -18.18010 4.15382   1.000 37.13857  ? 189 TYR A HD1  1 
ATOM   3120 H HD2  . TYR A 1 197 ? 34.42428  -21.55703 2.03960   1.000 30.36997  ? 189 TYR A HD2  1 
ATOM   3121 H HE1  . TYR A 1 197 ? 32.92215  -19.35211 5.80607   1.000 31.61292  ? 189 TYR A HE1  1 
ATOM   3122 H HE2  . TYR A 1 197 ? 33.30101  -22.72147 3.68253   1.000 35.71259  ? 189 TYR A HE2  1 
ATOM   3123 H HH   . TYR A 1 197 ? 32.21783  -22.65765 5.61617   1.000 51.44353  ? 189 TYR A HH   1 
ATOM   3124 N N    . VAL A 1 198 ? 32.33009  -19.25125 -0.59421  1.000 16.57989  ? 190 VAL A N    1 
ATOM   3125 C CA   . VAL A 1 198 ? 31.70537  -20.12278 -1.58742  1.000 13.60040  ? 190 VAL A CA   1 
ATOM   3126 C C    . VAL A 1 198 ? 31.28092  -19.26221 -2.75806  1.000 25.33054  ? 190 VAL A C    1 
ATOM   3127 O O    . VAL A 1 198 ? 31.06210  -18.04227 -2.61376  1.000 20.48302  ? 190 VAL A O    1 
ATOM   3128 C CB   . VAL A 1 198 ? 30.50774  -20.89933 -0.99096  1.000 16.10436  ? 190 VAL A CB   1 
ATOM   3129 C CG1  . VAL A 1 198 ? 30.97777  -21.81642 0.13736   1.000 19.76323  ? 190 VAL A CG1  1 
ATOM   3130 C CG2  . VAL A 1 198 ? 29.44707  -19.93252 -0.49669  1.000 20.97541  ? 190 VAL A CG2  1 
ATOM   3131 H H    . VAL A 1 198 ? 31.81315  -18.61927 -0.32408  1.000 19.91289  ? 190 VAL A H    1 
ATOM   3132 H HA   . VAL A 1 198 ? 32.36123  -20.76393 -1.90313  1.000 16.33750  ? 190 VAL A HA   1 
ATOM   3133 H HB   . VAL A 1 198 ? 30.11104  -21.45326 -1.68139  1.000 19.34226  ? 190 VAL A HB   1 
ATOM   3134 H HG11 . VAL A 1 198 ? 30.23023  -22.35704 0.43705   1.000 23.73290  ? 190 VAL A HG11 1 
ATOM   3135 H HG12 . VAL A 1 198 ? 31.68718  -22.38826 -0.19526  1.000 23.73290  ? 190 VAL A HG12 1 
ATOM   3136 H HG13 . VAL A 1 198 ? 31.30731  -21.27256 0.86983   1.000 23.73290  ? 190 VAL A HG13 1 
ATOM   3137 H HG21 . VAL A 1 198 ? 29.24518  -20.13235 0.43078   1.000 25.18752  ? 190 VAL A HG21 1 
ATOM   3138 H HG22 . VAL A 1 198 ? 29.78496  -19.02655 -0.57389  1.000 25.18752  ? 190 VAL A HG22 1 
ATOM   3139 H HG23 . VAL A 1 198 ? 28.64906  -20.03521 -1.03848  1.000 25.18752  ? 190 VAL A HG23 1 
ATOM   3140 N N    . PRO A 1 199 ? 31.09667  -19.85963 -3.93976  1.000 24.30643  ? 191 PRO A N    1 
ATOM   3141 C CA   . PRO A 1 199 ? 30.98257  -19.03455 -5.15545  1.000 34.75972  ? 191 PRO A CA   1 
ATOM   3142 C C    . PRO A 1 199 ? 29.64867  -18.32624 -5.29924  1.000 46.32911  ? 191 PRO A C    1 
ATOM   3143 O O    . PRO A 1 199 ? 29.62708  -17.14183 -5.65834  1.000 76.84394  ? 191 PRO A O    1 
ATOM   3144 C CB   . PRO A 1 199 ? 31.22086  -20.03879 -6.29486  1.000 24.40341  ? 191 PRO A CB   1 
ATOM   3145 C CG   . PRO A 1 199 ? 30.86196  -21.37190 -5.72345  1.000 31.79257  ? 191 PRO A CG   1 
ATOM   3146 C CD   . PRO A 1 199 ? 31.17607  -21.30391 -4.23894  1.000 23.20128  ? 191 PRO A CD   1 
ATOM   3147 H HA   . PRO A 1 199 ? 31.69089  -18.37184 -5.15443  1.000 41.72868  ? 191 PRO A HA   1 
ATOM   3148 H HB2  . PRO A 1 199 ? 30.65226  -19.82112 -7.04999  1.000 29.30112  ? 191 PRO A HB2  1 
ATOM   3149 H HB3  . PRO A 1 199 ? 32.15255  -20.01666 -6.56387  1.000 29.30112  ? 191 PRO A HB3  1 
ATOM   3150 H HG2  . PRO A 1 199 ? 29.91750  -21.54191 -5.86485  1.000 38.16811  ? 191 PRO A HG2  1 
ATOM   3151 H HG3  . PRO A 1 199 ? 31.39122  -22.06211 -6.15285  1.000 38.16811  ? 191 PRO A HG3  1 
ATOM   3152 H HD2  . PRO A 1 199 ? 30.51997  -21.79950 -3.72434  1.000 27.85856  ? 191 PRO A HD2  1 
ATOM   3153 H HD3  . PRO A 1 199 ? 32.06591  -21.64528 -4.05851  1.000 27.85856  ? 191 PRO A HD3  1 
ATOM   3154 N N    . GLU A 1 200 ? 28.52574  -19.00705 -5.04614  1.000 42.15493  ? 192 GLU A N    1 
ATOM   3155 C CA   . GLU A 1 200 ? 27.20350  -18.39853 -5.21811  1.000 62.96572  ? 192 GLU A CA   1 
ATOM   3156 C C    . GLU A 1 200 ? 26.35727  -18.71232 -3.98587  1.000 64.32317  ? 192 GLU A C    1 
ATOM   3157 O O    . GLU A 1 200 ? 25.46414  -19.56161 -4.01060  1.000 63.21344  ? 192 GLU A O    1 
ATOM   3158 C CB   . GLU A 1 200 ? 26.55442  -18.86211 -6.51690  1.000 61.83979  ? 192 GLU A CB   1 
ATOM   3159 C CG   . GLU A 1 200 ? 27.09015  -18.11328 -7.73675  1.000 73.58235  ? 192 GLU A CG   1 
ATOM   3160 C CD   . GLU A 1 200 ? 26.72392  -18.77386 -9.04552  1.000 80.04965  ? 192 GLU A CD   1 
ATOM   3161 O OE1  . GLU A 1 200 ? 27.12614  -19.93704 -9.26099  1.000 73.12741  ? 192 GLU A OE1  1 
ATOM   3162 O OE2  . GLU A 1 200 ? 26.05277  -18.11696 -9.87000  1.000 78.72235  ? 192 GLU A OE2  1 
ATOM   3163 N N    . PHE A 1 201 ? 26.66268  -18.00020 -2.90498  1.000 40.76712  ? 193 PHE A N    1 
ATOM   3164 C CA   . PHE A 1 201 ? 25.92136  -18.11266 -1.65801  1.000 43.81475  ? 193 PHE A CA   1 
ATOM   3165 C C    . PHE A 1 201 ? 24.45683  -17.74715 -1.87012  1.000 51.63146  ? 193 PHE A C    1 
ATOM   3166 O O    . PHE A 1 201 ? 24.14313  -16.66389 -2.37215  1.000 37.48394  ? 193 PHE A O    1 
ATOM   3167 C CB   . PHE A 1 201 ? 26.56570  -17.19077 -0.62452  1.000 36.01771  ? 193 PHE A CB   1 
ATOM   3168 C CG   . PHE A 1 201 ? 25.97038  -17.28237 0.74006   1.000 33.40040  ? 193 PHE A CG   1 
ATOM   3169 C CD1  . PHE A 1 201 ? 26.36614  -18.27515 1.61383   1.000 31.55151  ? 193 PHE A CD1  1 
ATOM   3170 C CD2  . PHE A 1 201 ? 25.03253  -16.35327 1.16438   1.000 31.37659  ? 193 PHE A CD2  1 
ATOM   3171 C CE1  . PHE A 1 201 ? 25.82331  -18.36035 2.88547   1.000 32.81187  ? 193 PHE A CE1  1 
ATOM   3172 C CE2  . PHE A 1 201 ? 24.49168  -16.43133 2.43278   1.000 48.81258  ? 193 PHE A CE2  1 
ATOM   3173 C CZ   . PHE A 1 201 ? 24.89035  -17.43938 3.29546   1.000 43.41009  ? 193 PHE A CZ   1 
ATOM   3174 N N    . THR A 1 202 ? 23.55924  -18.65046 -1.49135  1.000 61.35816  ? 194 THR A N    1 
ATOM   3175 C CA   . THR A 1 202 ? 22.12757  -18.42992 -1.64340  1.000 68.98189  ? 194 THR A CA   1 
ATOM   3176 C C    . THR A 1 202 ? 21.53161  -17.90835 -0.34237  1.000 61.48781  ? 194 THR A C    1 
ATOM   3177 O O    . THR A 1 202 ? 21.90314  -18.35288 0.74787   1.000 47.81375  ? 194 THR A O    1 
ATOM   3178 C CB   . THR A 1 202 ? 21.40511  -19.71503 -2.05725  1.000 67.73969  ? 194 THR A CB   1 
ATOM   3179 O OG1  . THR A 1 202 ? 21.57675  -20.71229 -1.04133  1.000 50.49123  ? 194 THR A OG1  1 
ATOM   3180 C CG2  . THR A 1 202 ? 21.94907  -20.23392 -3.38323  1.000 64.49515  ? 194 THR A CG2  1 
ATOM   3181 N N    . MET A 1 203 ? 20.60876  -16.95618 -0.46650  1.000 57.87168  ? 195 MET A N    1 
ATOM   3182 C CA   . MET A 1 203 ? 19.84702  -16.45541 0.66883   1.000 64.26102  ? 195 MET A CA   1 
ATOM   3183 C C    . MET A 1 203 ? 18.62006  -17.30718 0.97799   1.000 39.34889  ? 195 MET A C    1 
ATOM   3184 O O    . MET A 1 203 ? 18.03982  -17.16512 2.06055   1.000 43.79460  ? 195 MET A O    1 
ATOM   3185 C CB   . MET A 1 203 ? 19.42225  -15.00371 0.40922   1.000 44.31680  ? 195 MET A CB   1 
ATOM   3186 C CG   . MET A 1 203 ? 18.66345  -14.35621 1.55300   1.000 58.87988  ? 195 MET A CG   1 
ATOM   3187 S SD   . MET A 1 203 ? 19.65641  -14.21621 3.05006   1.000 52.76708  ? 195 MET A SD   1 
ATOM   3188 C CE   . MET A 1 203 ? 20.64393  -12.77293 2.67477   1.000 26.02623  ? 195 MET A CE   1 
ATOM   3189 N N    . TYR A 1 204 ? 18.23132  -18.19519 0.06645   1.000 54.83414  ? 196 TYR A N    1 
ATOM   3190 C CA   . TYR A 1 204 ? 17.06024  -19.04208 0.23408   1.000 55.42672  ? 196 TYR A CA   1 
ATOM   3191 C C    . TYR A 1 204 ? 17.17499  -20.20406 -0.74209  1.000 54.33966  ? 196 TYR A C    1 
ATOM   3192 O O    . TYR A 1 204 ? 17.86991  -20.11616 -1.75741  1.000 58.18171  ? 196 TYR A O    1 
ATOM   3193 C CB   . TYR A 1 204 ? 15.76992  -18.25220 0.00470   1.000 38.63221  ? 196 TYR A CB   1 
ATOM   3194 C CG   . TYR A 1 204 ? 15.88410  -17.25444 -1.12269  1.000 34.99492  ? 196 TYR A CG   1 
ATOM   3195 C CD1  . TYR A 1 204 ? 15.75624  -17.65694 -2.44320  1.000 43.98284  ? 196 TYR A CD1  1 
ATOM   3196 C CD2  . TYR A 1 204 ? 16.14036  -15.91400 -0.86915  1.000 39.06397  ? 196 TYR A CD2  1 
ATOM   3197 C CE1  . TYR A 1 204 ? 15.86516  -16.75238 -3.47967  1.000 59.57921  ? 196 TYR A CE1  1 
ATOM   3198 C CE2  . TYR A 1 204 ? 16.25477  -14.99892 -1.90292  1.000 35.67857  ? 196 TYR A CE2  1 
ATOM   3199 C CZ   . TYR A 1 204 ? 16.11507  -15.42508 -3.20375  1.000 30.17812  ? 196 TYR A CZ   1 
ATOM   3200 O OH   . TYR A 1 204 ? 16.22680  -14.52994 -4.24250  1.000 51.01614  ? 196 TYR A OH   1 
ATOM   3201 N N    . SER A 1 205 ? 16.48095  -21.29348 -0.42354  1.000 71.73472  ? 197 SER A N    1 
ATOM   3202 C CA   . SER A 1 205 ? 16.62179  -22.52446 -1.18818  1.000 63.81261  ? 197 SER A CA   1 
ATOM   3203 C C    . SER A 1 205 ? 16.05860  -22.36812 -2.60096  1.000 70.20503  ? 197 SER A C    1 
ATOM   3204 O O    . SER A 1 205 ? 15.29599  -21.44485 -2.90393  1.000 53.61596  ? 197 SER A O    1 
ATOM   3205 C CB   . SER A 1 205 ? 15.92465  -23.68155 -0.47146  1.000 56.28496  ? 197 SER A CB   1 
ATOM   3206 O OG   . SER A 1 205 ? 14.52863  -23.45205 -0.37017  1.000 52.29008  ? 197 SER A OG   1 
ATOM   3207 N N    . ALA A 1 206 ? 16.44740  -23.30435 -3.47207  1.000 60.55426  ? 198 ALA A N    1 
ATOM   3208 C CA   . ALA A 1 206 ? 16.01020  -23.25537 -4.86416  1.000 66.59015  ? 198 ALA A CA   1 
ATOM   3209 C C    . ALA A 1 206 ? 14.49744  -23.39995 -4.97585  1.000 84.98181  ? 198 ALA A C    1 
ATOM   3210 O O    . ALA A 1 206 ? 13.86864  -22.78092 -5.84306  1.000 87.00552  ? 198 ALA A O    1 
ATOM   3211 C CB   . ALA A 1 206 ? 16.71629  -24.34496 -5.67370  1.000 51.57071  ? 198 ALA A CB   1 
ATOM   3212 N N    . ASN A 1 207 ? 13.89909  -24.22360 -4.12024  1.000 80.10881  ? 199 ASN A N    1 
ATOM   3213 C CA   . ASN A 1 207 ? 12.45307  -24.42111 -4.12221  1.000 80.48941  ? 199 ASN A CA   1 
ATOM   3214 C C    . ASN A 1 207 ? 11.88935  -24.25114 -2.71404  1.000 70.70375  ? 199 ASN A C    1 
ATOM   3215 O O    . ASN A 1 207 ? 10.70270  -24.47343 -2.47677  1.000 84.91747  ? 199 ASN A O    1 
ATOM   3216 C CB   . ASN A 1 207 ? 12.09498  -25.80330 -4.67872  1.000 73.27884  ? 199 ASN A CB   1 
ATOM   3217 C CG   . ASN A 1 207 ? 12.85323  -26.13726 -5.95472  1.000 85.29803  ? 199 ASN A CG   1 
ATOM   3218 O OD1  . ASN A 1 207 ? 14.06905  -25.95555 -6.03802  1.000 75.65180  ? 199 ASN A OD1  1 
ATOM   3219 N ND2  . ASN A 1 207 ? 12.13593  -26.63461 -6.95393  1.000 93.44892  ? 199 ASN A ND2  1 
ATOM   3220 N N    . ALA A 1 212 ? 9.43803   -21.30069 1.30804   1.000 70.16784  ? 204 ALA A N    1 
ATOM   3221 C CA   . ALA A 1 212 ? 10.83525  -20.88619 1.23437   1.000 70.26558  ? 204 ALA A CA   1 
ATOM   3222 C C    . ALA A 1 212 ? 11.25958  -20.09059 2.46904   1.000 58.30360  ? 204 ALA A C    1 
ATOM   3223 O O    . ALA A 1 212 ? 10.53732  -19.17017 2.90955   1.000 75.72944  ? 204 ALA A O    1 
ATOM   3224 C CB   . ALA A 1 212 ? 11.07730  -20.08498 -0.04668  1.000 34.86405  ? 204 ALA A CB   1 
ATOM   3225 N N    . LYS A 1 213 ? 12.42611  -20.45140 3.01496   1.000 56.79777  ? 205 LYS A N    1 
ATOM   3226 C CA   . LYS A 1 213 ? 12.97632  -19.86452 4.22006   1.000 58.94667  ? 205 LYS A CA   1 
ATOM   3227 C C    . LYS A 1 213 ? 14.29154  -19.18731 3.88929   1.000 54.51411  ? 205 LYS A C    1 
ATOM   3228 O O    . LYS A 1 213 ? 14.93941  -19.52873 2.88390   1.000 52.37298  ? 205 LYS A O    1 
ATOM   3229 C CB   . LYS A 1 213 ? 13.16571  -20.94282 5.31969   1.000 62.29279  ? 205 LYS A CB   1 
ATOM   3230 C CG   . LYS A 1 213 ? 12.01875  -21.05698 6.31494   1.000 78.92384  ? 205 LYS A CG   1 
ATOM   3231 C CD   . LYS A 1 213 ? 12.01842  -22.38616 7.05724   1.000 77.84873  ? 205 LYS A CD   1 
ATOM   3232 C CE   . LYS A 1 213 ? 11.41568  -22.23973 8.44999   1.000 79.28175  ? 205 LYS A CE   1 
ATOM   3233 N NZ   . LYS A 1 213 ? 12.27418  -21.40683 9.34087   1.000 71.57773  ? 205 LYS A NZ   1 
ATOM   3234 N N    . LEU A 1 214 ? 14.74938  -18.28899 4.77612   1.000 28.58392  ? 206 LEU A N    1 
ATOM   3235 C CA   . LEU A 1 214 ? 16.01174  -17.60600 4.54103   1.000 28.96100  ? 206 LEU A CA   1 
ATOM   3236 C C    . LEU A 1 214 ? 17.18375  -18.40942 5.09656   1.000 26.88730  ? 206 LEU A C    1 
ATOM   3237 O O    . LEU A 1 214 ? 17.06975  -19.09612 6.11432   1.000 43.97888  ? 206 LEU A O    1 
ATOM   3238 C CB   . LEU A 1 214 ? 16.02508  -16.21152 5.16759   1.000 27.72761  ? 206 LEU A CB   1 
ATOM   3239 C CG   . LEU A 1 214 ? 15.05417  -15.18171 4.59272   1.000 21.95410  ? 206 LEU A CG   1 
ATOM   3240 C CD1  . LEU A 1 214 ? 15.15108  -13.87282 5.39675   1.000 22.74975  ? 206 LEU A CD1  1 
ATOM   3241 C CD2  . LEU A 1 214 ? 15.32443  -14.92868 3.12594   1.000 21.05268  ? 206 LEU A CD2  1 
ATOM   3242 H HA   . LEU A 1 214 ? 16.12400  -17.50748 3.58260   1.000 34.77022  ? 206 LEU A HA   1 
ATOM   3243 H HB2  . LEU A 1 214 ? 15.81222  -16.30569 6.10925   1.000 33.29016  ? 206 LEU A HB2  1 
ATOM   3244 H HB3  . LEU A 1 214 ? 16.91788  -15.84668 5.06414   1.000 33.29016  ? 206 LEU A HB3  1 
ATOM   3245 H HG   . LEU A 1 214 ? 14.15000  -15.52618 4.66134   1.000 26.36194  ? 206 LEU A HG   1 
ATOM   3246 H HD11 . LEU A 1 214 ? 14.68085  -13.17248 4.91788   1.000 27.31673  ? 206 LEU A HD11 1 
ATOM   3247 H HD12 . LEU A 1 214 ? 14.74653  -14.00677 6.26812   1.000 27.31673  ? 206 LEU A HD12 1 
ATOM   3248 H HD13 . LEU A 1 214 ? 16.08551  -13.63354 5.49914   1.000 27.31673  ? 206 LEU A HD13 1 
ATOM   3249 H HD21 . LEU A 1 214 ? 14.87407  -14.11240 2.85807   1.000 25.28023  ? 206 LEU A HD21 1 
ATOM   3250 H HD22 . LEU A 1 214 ? 16.28086  -14.83798 2.99211   1.000 25.28023  ? 206 LEU A HD22 1 
ATOM   3251 H HD23 . LEU A 1 214 ? 14.98762  -15.67721 2.60906   1.000 25.28023  ? 206 LEU A HD23 1 
ATOM   3252 N N    . SER A 1 215 ? 18.32942  -18.30373 4.41852   1.000 33.96996  ? 207 SER A N    1 
ATOM   3253 C CA   . SER A 1 215 ? 19.53112  -18.99622 4.87667   1.000 52.06867  ? 207 SER A CA   1 
ATOM   3254 C C    . SER A 1 215 ? 20.27374  -18.18524 5.93467   1.000 54.33892  ? 207 SER A C    1 
ATOM   3255 O O    . SER A 1 215 ? 20.84138  -18.75485 6.87560   1.000 40.37677  ? 207 SER A O    1 
ATOM   3256 C CB   . SER A 1 215 ? 20.45291  -19.28170 3.69218   1.000 37.62635  ? 207 SER A CB   1 
ATOM   3257 O OG   . SER A 1 215 ? 21.01143  -18.07505 3.18554   1.000 50.53753  ? 207 SER A OG   1 
ATOM   3258 H H    . SER A 1 215 ? 18.43453  -17.84309 3.69994   1.000 40.78097  ? 207 SER A H    1 
ATOM   3259 H HA   . SER A 1 215 ? 19.27130  -19.84371 5.27056   1.000 62.49943  ? 207 SER A HA   1 
ATOM   3260 H HB2  . SER A 1 215 ? 21.17133  -19.86446 3.98399   1.000 45.16865  ? 207 SER A HB2  1 
ATOM   3261 H HB3  . SER A 1 215 ? 19.94092  -19.71236 2.98982   1.000 45.16865  ? 207 SER A HB3  1 
ATOM   3262 H HG   . SER A 1 215 ? 21.53660  -18.24518 2.55241   1.000 60.66205  ? 207 SER A HG   1 
ATOM   3263 N N    . VAL A 1 216 ? 20.27295  -16.86115 5.79509   1.000 36.87001  ? 208 VAL A N    1 
ATOM   3264 C CA   . VAL A 1 216 ? 20.92298  -15.95163 6.73252   1.000 25.74487  ? 208 VAL A CA   1 
ATOM   3265 C C    . VAL A 1 216 ? 19.83435  -15.13920 7.41760   1.000 25.37619  ? 208 VAL A C    1 
ATOM   3266 O O    . VAL A 1 216 ? 19.03958  -14.46971 6.74868   1.000 23.45401  ? 208 VAL A O    1 
ATOM   3267 C CB   . VAL A 1 216 ? 21.92619  -15.03107 6.02396   1.000 33.58746  ? 208 VAL A CB   1 
ATOM   3268 C CG1  . VAL A 1 216 ? 22.60186  -14.12907 7.02679   1.000 30.10453  ? 208 VAL A CG1  1 
ATOM   3269 C CG2  . VAL A 1 216 ? 22.94903  -15.84850 5.25400   1.000 41.71625  ? 208 VAL A CG2  1 
ATOM   3270 H H    . VAL A 1 216 ? 19.88878  -16.45378 5.14236   1.000 44.26103  ? 208 VAL A H    1 
ATOM   3271 H HA   . VAL A 1 216 ? 21.39842  -16.46564 7.40383   1.000 30.91086  ? 208 VAL A HA   1 
ATOM   3272 H HB   . VAL A 1 216 ? 21.45211  -14.47423 5.38671   1.000 40.32198  ? 208 VAL A HB   1 
ATOM   3273 H HG11 . VAL A 1 216 ? 23.23863  -13.56274 6.56343   1.000 36.14246  ? 208 VAL A HG11 1 
ATOM   3274 H HG12 . VAL A 1 216 ? 21.92968  -13.58269 7.46330   1.000 36.14246  ? 208 VAL A HG12 1 
ATOM   3275 H HG13 . VAL A 1 216 ? 23.06160  -14.67531 7.68341   1.000 36.14246  ? 208 VAL A HG13 1 
ATOM   3276 H HG21 . VAL A 1 216 ? 23.57068  -15.24570 4.81686   1.000 50.07652  ? 208 VAL A HG21 1 
ATOM   3277 H HG22 . VAL A 1 216 ? 23.42554  -16.42278 5.87371   1.000 50.07652  ? 208 VAL A HG22 1 
ATOM   3278 H HG23 . VAL A 1 216 ? 22.48885  -16.38685 4.59120   1.000 50.07652  ? 208 VAL A HG23 1 
ATOM   3279 N N    . GLY A 1 217 ? 19.78604  -15.20639 8.74401   1.000 23.94675  ? 209 GLY A N    1 
ATOM   3280 C CA   . GLY A 1 217 ? 18.79295  -14.43943 9.47907   1.000 27.49489  ? 209 GLY A CA   1 
ATOM   3281 C C    . GLY A 1 217 ? 17.38082  -14.97673 9.29441   1.000 27.11279  ? 209 GLY A C    1 
ATOM   3282 O O    . GLY A 1 217 ? 17.15504  -16.16956 9.07216   1.000 25.76843  ? 209 GLY A O    1 
ATOM   3283 H H    . GLY A 1 217 ? 20.30934  -15.68156 9.23387   1.000 28.75313  ? 209 GLY A H    1 
ATOM   3284 H HA2  . GLY A 1 217 ? 19.00619  -14.46334 10.42504  1.000 33.01089  ? 209 GLY A HA2  1 
ATOM   3285 H HA3  . GLY A 1 217 ? 18.81025  -13.51861 9.17461   1.000 33.01089  ? 209 GLY A HA3  1 
ATOM   3286 N N    . SER A 1 218 ? 16.41012  -14.07457 9.38811   1.000 17.21814  ? 210 SER A N    1 
ATOM   3287 C CA   . SER A 1 218 ? 15.00740  -14.44678 9.32407   1.000 18.38702  ? 210 SER A CA   1 
ATOM   3288 C C    . SER A 1 218 ? 14.22020  -13.22996 8.87376   1.000 18.32720  ? 210 SER A C    1 
ATOM   3289 O O    . SER A 1 218 ? 14.73384  -12.10492 8.93496   1.000 14.16657  ? 210 SER A O    1 
ATOM   3290 C CB   . SER A 1 218 ? 14.49661  -14.94153 10.68370  1.000 21.42326  ? 210 SER A CB   1 
ATOM   3291 O OG   . SER A 1 218 ? 14.52410  -13.90329 11.65195  1.000 21.71926  ? 210 SER A OG   1 
ATOM   3292 H H    . SER A 1 218 ? 16.54300  -13.23107 9.49036   1.000 20.67879  ? 210 SER A H    1 
ATOM   3293 H HA   . SER A 1 218 ? 14.88578  -15.15752 8.67527   1.000 22.08144  ? 210 SER A HA   1 
ATOM   3294 H HB2  . SER A 1 218 ? 13.58340  -15.25237 10.58213  1.000 25.72494  ? 210 SER A HB2  1 
ATOM   3295 H HB3  . SER A 1 218 ? 15.06282  -15.66861 10.98646  1.000 25.72494  ? 210 SER A HB3  1 
ATOM   3296 H HG   . SER A 1 218 ? 13.74292  -13.72451 11.90375  1.000 26.08013  ? 210 SER A HG   1 
ATOM   3297 N N    . PRO A 1 219 ? 12.99055  -13.42479 8.38476   1.000 16.29500  ? 211 PRO A N    1 
ATOM   3298 C CA   . PRO A 1 219 ? 12.19687  -12.25574 7.94382   1.000 14.02127  ? 211 PRO A CA   1 
ATOM   3299 C C    . PRO A 1 219 ? 12.00029  -11.21678 9.03122   1.000 17.25661  ? 211 PRO A C    1 
ATOM   3300 O O    . PRO A 1 219 ? 12.08711  -10.01260 8.74218   1.000 14.54142  ? 211 PRO A O    1 
ATOM   3301 C CB   . PRO A 1 219 ? 10.85909  -12.86909 7.49137   1.000 18.01965  ? 211 PRO A CB   1 
ATOM   3302 C CG   . PRO A 1 219 ? 11.21197  -14.29967 7.11786   1.000 22.33523  ? 211 PRO A CG   1 
ATOM   3303 C CD   . PRO A 1 219 ? 12.33336  -14.70815 8.06778   1.000 22.05106  ? 211 PRO A CD   1 
ATOM   3304 H HA   . PRO A 1 219 ? 12.63040  -11.84586 7.17901   1.000 16.84254  ? 211 PRO A HA   1 
ATOM   3305 H HB2  . PRO A 1 219 ? 10.21834  -12.84527 8.21922   1.000 21.64060  ? 211 PRO A HB2  1 
ATOM   3306 H HB3  . PRO A 1 219 ? 10.51124  -12.38345 6.72713   1.000 21.64060  ? 211 PRO A HB3  1 
ATOM   3307 H HG2  . PRO A 1 219 ? 10.43633  -14.87018 7.23531   1.000 26.81930  ? 211 PRO A HG2  1 
ATOM   3308 H HG3  . PRO A 1 219 ? 11.51215  -14.33348 6.19609   1.000 26.81930  ? 211 PRO A HG3  1 
ATOM   3309 H HD2  . PRO A 1 219 ? 11.97448  -15.11995 8.86936   1.000 26.47830  ? 211 PRO A HD2  1 
ATOM   3310 H HD3  . PRO A 1 219 ? 12.95197  -15.31478 7.63163   1.000 26.47830  ? 211 PRO A HD3  1 
ATOM   3311 N N    . ASP A 1 220 ? 11.72839  -11.64641 10.27168  1.000 16.43551  ? 212 ASP A N    1 
ATOM   3312 C CA   . ASP A 1 220 ? 11.53593  -10.68836 11.35306  1.000 15.31290  ? 212 ASP A CA   1 
ATOM   3313 C C    . ASP A 1 220 ? 12.82808  -9.94866  11.65997  1.000 11.30682  ? 212 ASP A C    1 
ATOM   3314 O O    . ASP A 1 220 ? 12.80833  -8.74046  11.93261  1.000 12.52502  ? 212 ASP A O    1 
ATOM   3315 C CB   . ASP A 1 220 ? 11.00289  -11.38026 12.61287  1.000 16.91343  ? 212 ASP A CB   1 
ATOM   3316 C CG   . ASP A 1 220 ? 11.77346  -12.61381 12.97617  1.000 32.44560  ? 212 ASP A CG   1 
ATOM   3317 O OD1  . ASP A 1 220 ? 11.85738  -13.53317 12.13023  1.000 37.14857  ? 212 ASP A OD1  1 
ATOM   3318 O OD2  . ASP A 1 220 ? 12.27978  -12.66393 14.11998  1.000 39.19184  ? 212 ASP A OD2  1 
ATOM   3319 H H    . ASP A 1 220 ? 11.65273  -12.47119 10.50322  1.000 19.73964  ? 212 ASP A H    1 
ATOM   3320 H HA   . ASP A 1 220 ? 10.86759  -10.04356 11.07295  1.000 18.39250  ? 212 ASP A HA   1 
ATOM   3321 H HB2  . ASP A 1 220 ? 11.05876  -10.76275 13.35884  1.000 20.31314  ? 212 ASP A HB2  1 
ATOM   3322 H HB3  . ASP A 1 220 ? 10.07968  -11.63793 12.46392  1.000 20.31314  ? 212 ASP A HB3  1 
ATOM   3323 N N    . PHE A 1 221 ? 13.96697  -10.65020 11.61354  1.000 12.61344  ? 213 PHE A N    1 
ATOM   3324 C CA   . PHE A 1 221 ? 15.24485  -9.98562  11.85493  1.000 13.60341  ? 213 PHE A CA   1 
ATOM   3325 C C    . PHE A 1 221 ? 15.49718  -8.89563  10.81660  1.000 13.22650  ? 213 PHE A C    1 
ATOM   3326 O O    . PHE A 1 221 ? 15.86230  -7.76398  11.15851  1.000 11.11195  ? 213 PHE A O    1 
ATOM   3327 C CB   . PHE A 1 221 ? 16.38967  -11.00973 11.84784  1.000 12.66299  ? 213 PHE A CB   1 
ATOM   3328 C CG   . PHE A 1 221 ? 17.76535  -10.38501 11.85746  1.000 11.83684  ? 213 PHE A CG   1 
ATOM   3329 C CD1  . PHE A 1 221 ? 18.35788  -10.00353 13.05585  1.000 16.78795  ? 213 PHE A CD1  1 
ATOM   3330 C CD2  . PHE A 1 221 ? 18.45326  -10.17594 10.67398  1.000 12.31449  ? 213 PHE A CD2  1 
ATOM   3331 C CE1  . PHE A 1 221 ? 19.61660  -9.42179  13.07289  1.000 15.27497  ? 213 PHE A CE1  1 
ATOM   3332 C CE2  . PHE A 1 221 ? 19.71332  -9.58716  10.67125  1.000 11.70673  ? 213 PHE A CE2  1 
ATOM   3333 C CZ   . PHE A 1 221 ? 20.29915  -9.20877  11.89056  1.000 15.25329  ? 213 PHE A CZ   1 
ATOM   3334 H H    . PHE A 1 221 ? 14.02261  -11.49228 11.44796  1.000 15.15315  ? 213 PHE A H    1 
ATOM   3335 H HA   . PHE A 1 221 ? 15.21826  -9.57339  12.73258  1.000 16.34111  ? 213 PHE A HA   1 
ATOM   3336 H HB2  . PHE A 1 221 ? 16.31290  -11.56879 12.63680  1.000 15.21262  ? 213 PHE A HB2  1 
ATOM   3337 H HB3  . PHE A 1 221 ? 16.31695  -11.55326 11.04772  1.000 15.21262  ? 213 PHE A HB3  1 
ATOM   3338 H HD1  . PHE A 1 221 ? 17.90439  -10.14020 13.85620  1.000 20.16256  ? 213 PHE A HD1  1 
ATOM   3339 H HD2  . PHE A 1 221 ? 18.06659  -10.43327 9.86827   1.000 14.79442  ? 213 PHE A HD2  1 
ATOM   3340 H HE1  . PHE A 1 221 ? 20.00230  -9.17440  13.88216  1.000 18.34699  ? 213 PHE A HE1  1 
ATOM   3341 H HE2  . PHE A 1 221 ? 20.16361  -9.44538  9.86998   1.000 14.06509  ? 213 PHE A HE2  1 
ATOM   3342 H HZ   . PHE A 1 221 ? 21.14240  -8.81674  11.90199  1.000 18.32097  ? 213 PHE A HZ   1 
ATOM   3343 N N    . TRP A 1 222 ? 15.30557  -9.21639  9.53371   1.000 11.86373  ? 214 TRP A N    1 
ATOM   3344 C CA   . TRP A 1 222 ? 15.65843  -8.26853  8.48408   1.000 10.42575  ? 214 TRP A CA   1 
ATOM   3345 C C    . TRP A 1 222 ? 14.67455  -7.10928  8.40571   1.000 11.71365  ? 214 TRP A C    1 
ATOM   3346 O O    . TRP A 1 222 ? 15.07261  -5.96657  8.14621   1.000 10.64469  ? 214 TRP A O    1 
ATOM   3347 C CB   . TRP A 1 222 ? 15.74033  -8.98896  7.14779   1.000 11.87534  ? 214 TRP A CB   1 
ATOM   3348 C CG   . TRP A 1 222 ? 16.97812  -9.82739  7.02647   1.000 12.24494  ? 214 TRP A CG   1 
ATOM   3349 C CD1  . TRP A 1 222 ? 17.03231  -11.18684 6.93315   1.000 17.62523  ? 214 TRP A CD1  1 
ATOM   3350 C CD2  . TRP A 1 222 ? 18.34477  -9.37408  7.03170   1.000 10.41627  ? 214 TRP A CD2  1 
ATOM   3351 N NE1  . TRP A 1 222 ? 18.33962  -11.60742 6.85812   1.000 15.31562  ? 214 TRP A NE1  1 
ATOM   3352 C CE2  . TRP A 1 222 ? 19.16201  -10.51931 6.91626   1.000 13.51310  ? 214 TRP A CE2  1 
ATOM   3353 C CE3  . TRP A 1 222 ? 18.94929  -8.12217  7.11657   1.000 12.53492  ? 214 TRP A CE3  1 
ATOM   3354 C CZ2  . TRP A 1 222 ? 20.55053  -10.43594 6.86460   1.000 13.95853  ? 214 TRP A CZ2  1 
ATOM   3355 C CZ3  . TRP A 1 222 ? 20.31377  -8.04099  7.06603   1.000 17.65438  ? 214 TRP A CZ3  1 
ATOM   3356 C CH2  . TRP A 1 222 ? 21.10724  -9.19561  6.95925   1.000 13.15645  ? 214 TRP A CH2  1 
ATOM   3357 H H    . TRP A 1 222 ? 14.97958  -9.96125  9.25352   1.000 14.25350  ? 214 TRP A H    1 
ATOM   3358 H HA   . TRP A 1 222 ? 16.53029  -7.89569  8.68843   1.000 12.52792  ? 214 TRP A HA   1 
ATOM   3359 H HB2  . TRP A 1 222 ? 14.97056  -9.57164  7.05372   1.000 14.26743  ? 214 TRP A HB2  1 
ATOM   3360 H HB3  . TRP A 1 222 ? 15.74895  -8.33275  6.43350   1.000 14.26743  ? 214 TRP A HB3  1 
ATOM   3361 H HD1  . TRP A 1 222 ? 16.29149  -11.74894 6.92185   1.000 21.16730  ? 214 TRP A HD1  1 
ATOM   3362 H HE1  . TRP A 1 222 ? 18.59758  -12.42465 6.78613   1.000 18.39577  ? 214 TRP A HE1  1 
ATOM   3363 H HE3  . TRP A 1 222 ? 18.43338  -7.35361  7.20618   1.000 15.05893  ? 214 TRP A HE3  1 
ATOM   3364 H HZ2  . TRP A 1 222 ? 21.07735  -11.19638 6.76929   1.000 16.76726  ? 214 TRP A HZ2  1 
ATOM   3365 H HZ3  . TRP A 1 222 ? 20.72348  -7.20692  7.10300   1.000 21.20228  ? 214 TRP A HZ3  1 
ATOM   3366 H HH2  . TRP A 1 222 ? 22.03341  -9.11154  6.95302   1.000 15.80476  ? 214 TRP A HH2  1 
ATOM   3367 N N    . ILE A 1 223 ? 13.38663  -7.36833  8.62303   1.000 11.16622  ? 215 ILE A N    1 
ATOM   3368 C CA   . ILE A 1 223 ? 12.45472  -6.25390  8.52243   1.000 9.61404   ? 215 ILE A CA   1 
ATOM   3369 C C    . ILE A 1 223 ? 12.67136  -5.28882  9.67575   1.000 10.31494  ? 215 ILE A C    1 
ATOM   3370 O O    . ILE A 1 223 ? 12.49943  -4.06934  9.52038   1.000 10.43445  ? 215 ILE A O    1 
ATOM   3371 C CB   . ILE A 1 223 ? 11.00041  -6.75073  8.45581   1.000 11.89630  ? 215 ILE A CB   1 
ATOM   3372 C CG1  . ILE A 1 223 ? 10.12932  -5.64708  7.84734   1.000 9.78764   ? 215 ILE A CG1  1 
ATOM   3373 C CG2  . ILE A 1 223 ? 10.45134  -7.10829  9.82658   1.000 13.01898  ? 215 ILE A CG2  1 
ATOM   3374 C CD1  . ILE A 1 223 ? 10.27039  -5.48652  6.33294   1.000 11.10875  ? 215 ILE A CD1  1 
ATOM   3375 H H    . ILE A 1 223 ? 13.04861  -8.13461  8.81837   1.000 13.41649  ? 215 ILE A H    1 
ATOM   3376 H HA   . ILE A 1 223 ? 12.62853  -5.78235  7.69277   1.000 11.55387  ? 215 ILE A HA   1 
ATOM   3377 H HB   . ILE A 1 223 ? 10.98780  -7.55250  7.91000   1.000 14.29258  ? 215 ILE A HB   1 
ATOM   3378 H HG12 . ILE A 1 223 ? 9.19934   -5.84956  8.03454   1.000 11.76220  ? 215 ILE A HG12 1 
ATOM   3379 H HG13 . ILE A 1 223 ? 10.37329  -4.80141  8.25503   1.000 11.76220  ? 215 ILE A HG13 1 
ATOM   3380 H HG21 . ILE A 1 223 ? 9.64110   -7.62999  9.71597   1.000 15.63980  ? 215 ILE A HG21 1 
ATOM   3381 H HG22 . ILE A 1 223 ? 11.11544  -7.62661  10.30741  1.000 15.63980  ? 215 ILE A HG22 1 
ATOM   3382 H HG23 . ILE A 1 223 ? 10.25509  -6.29122  10.31112  1.000 15.63980  ? 215 ILE A HG23 1 
ATOM   3383 H HD11 . ILE A 1 223 ? 9.66880   -4.78761  6.03207   1.000 13.34752  ? 215 ILE A HD11 1 
ATOM   3384 H HD12 . ILE A 1 223 ? 11.18685  -5.24633  6.12485   1.000 13.34752  ? 215 ILE A HD12 1 
ATOM   3385 H HD13 . ILE A 1 223 ? 10.04290  -6.32615  5.90380   1.000 13.34752  ? 215 ILE A HD13 1 
ATOM   3386 N N    . ARG A 1 224 ? 13.08325  -5.80765  10.83893  1.000 10.78864  ? 216 ARG A N    1 
ATOM   3387 C CA   . ARG A 1 224 ? 13.32884  -4.94265  11.98566  1.000 10.61618  ? 216 ARG A CA   1 
ATOM   3388 C C    . ARG A 1 224 ? 14.60879  -4.14517  11.80468  1.000 10.47700  ? 216 ARG A C    1 
ATOM   3389 O O    . ARG A 1 224 ? 14.65406  -2.95120  12.11735  1.000 10.69573  ? 216 ARG A O    1 
ATOM   3390 C CB   . ARG A 1 224 ? 13.35735  -5.78449  13.26343  1.000 10.74686  ? 216 ARG A CB   1 
ATOM   3391 C CG   . ARG A 1 224 ? 11.95034  -6.24651  13.64616  1.000 12.11806  ? 216 ARG A CG   1 
ATOM   3392 C CD   . ARG A 1 224 ? 11.91319  -7.27464  14.74294  1.000 11.34777  ? 216 ARG A CD   1 
ATOM   3393 N NE   . ARG A 1 224 ? 10.52327  -7.54649  15.13582  1.000 9.59612   ? 216 ARG A NE   1 
ATOM   3394 C CZ   . ARG A 1 224 ? 10.16076  -8.36481  16.12235  1.000 14.53559  ? 216 ARG A CZ   1 
ATOM   3395 N NH1  . ARG A 1 224 ? 11.07605  -9.00323  16.83747  1.000 15.08952  ? 216 ARG A NH1  1 
ATOM   3396 N NH2  . ARG A 1 224 ? 8.87830   -8.54280  16.40335  1.000 14.50532  ? 216 ARG A NH2  1 
ATOM   3397 H H    . ARG A 1 224 ? 13.22436  -6.64361  10.98337  1.000 12.96338  ? 216 ARG A H    1 
ATOM   3398 H HA   . ARG A 1 224 ? 12.60527  -4.30278  12.07464  1.000 12.75643  ? 216 ARG A HA   1 
ATOM   3399 H HB2  . ARG A 1 224 ? 13.91069  -6.56833  13.12094  1.000 12.91326  ? 216 ARG A HB2  1 
ATOM   3400 H HB3  . ARG A 1 224 ? 13.71573  -5.25332  13.99166  1.000 12.91326  ? 216 ARG A HB3  1 
ATOM   3401 H HG2  . ARG A 1 224 ? 11.44244  -5.47737  13.94840  1.000 14.55869  ? 216 ARG A HG2  1 
ATOM   3402 H HG3  . ARG A 1 224 ? 11.52829  -6.63653  12.86471  1.000 14.55869  ? 216 ARG A HG3  1 
ATOM   3403 H HD2  . ARG A 1 224 ? 12.31465  -8.10027  14.42978  1.000 13.63435  ? 216 ARG A HD2  1 
ATOM   3404 H HD3  . ARG A 1 224 ? 12.39566  -6.94374  15.51665  1.000 13.63435  ? 216 ARG A HD3  1 
ATOM   3405 H HE   . ARG A 1 224 ? 9.89939   -7.14878  14.69742  1.000 11.53237  ? 216 ARG A HE   1 
ATOM   3406 H HH11 . ARG A 1 224 ? 11.91123  -8.89064  16.66600  1.000 18.12445  ? 216 ARG A HH11 1 
ATOM   3407 H HH12 . ARG A 1 224 ? 10.83476  -9.53006  17.47294  1.000 18.12445  ? 216 ARG A HH12 1 
ATOM   3408 H HH21 . ARG A 1 224 ? 8.27698   -8.12939  15.94827  1.000 17.42341  ? 216 ARG A HH21 1 
ATOM   3409 H HH22 . ARG A 1 224 ? 8.64716   -9.07175  17.04084  1.000 17.42341  ? 216 ARG A HH22 1 
ATOM   3410 N N    . TYR A 1 225 ? 15.66072  -4.79652  11.31403  1.000 10.15034  ? 217 TYR A N    1 
ATOM   3411 C CA   . TYR A 1 225 ? 16.88828  -4.10152  10.94539  1.000 8.80850   ? 217 TYR A CA   1 
ATOM   3412 C C    . TYR A 1 225 ? 16.61142  -2.98845  9.94119   1.000 10.73510  ? 217 TYR A C    1 
ATOM   3413 O O    . TYR A 1 225 ? 17.04185  -1.84034  10.12654  1.000 11.36095  ? 217 TYR A O    1 
ATOM   3414 C CB   . TYR A 1 225 ? 17.85376  -5.14162  10.37548  1.000 10.17453  ? 217 TYR A CB   1 
ATOM   3415 C CG   . TYR A 1 225 ? 19.34596  -4.88960  10.49153  1.000 10.49894  ? 217 TYR A CG   1 
ATOM   3416 C CD1  . TYR A 1 225 ? 19.84863  -3.66113  10.86617  1.000 10.28868  ? 217 TYR A CD1  1 
ATOM   3417 C CD2  . TYR A 1 225 ? 20.24842  -5.91013  10.20610  1.000 14.92987  ? 217 TYR A CD2  1 
ATOM   3418 C CE1  . TYR A 1 225 ? 21.20727  -3.43928  10.95362  1.000 14.34840  ? 217 TYR A CE1  1 
ATOM   3419 C CE2  . TYR A 1 225 ? 21.60533  -5.70826  10.30057  1.000 14.08630  ? 217 TYR A CE2  1 
ATOM   3420 C CZ   . TYR A 1 225 ? 22.08439  -4.47676  10.68007  1.000 12.25220  ? 217 TYR A CZ   1 
ATOM   3421 O OH   . TYR A 1 225 ? 23.44860  -4.27987  10.75660  1.000 17.14223  ? 217 TYR A OH   1 
ATOM   3422 H H    . TYR A 1 225 ? 15.68935  -5.64616  11.18409  1.000 12.19743  ? 217 TYR A H    1 
ATOM   3423 H HA   . TYR A 1 225 ? 17.29040  -3.68181  11.72196  1.000 10.58723  ? 217 TYR A HA   1 
ATOM   3424 H HB2  . TYR A 1 225 ? 17.68064  -5.98134  10.82914  1.000 12.22646  ? 217 TYR A HB2  1 
ATOM   3425 H HB3  . TYR A 1 225 ? 17.66276  -5.23055  9.42864   1.000 12.22646  ? 217 TYR A HB3  1 
ATOM   3426 H HD1  . TYR A 1 225 ? 19.26002  -2.96873  11.06372  1.000 12.36343  ? 217 TYR A HD1  1 
ATOM   3427 H HD2  . TYR A 1 225 ? 19.92786  -6.74372  9.94676   1.000 17.93287  ? 217 TYR A HD2  1 
ATOM   3428 H HE1  . TYR A 1 225 ? 21.53157  -2.60142  11.19388  1.000 17.23511  ? 217 TYR A HE1  1 
ATOM   3429 H HE2  . TYR A 1 225 ? 22.19561  -6.40086  10.10885  1.000 16.92058  ? 217 TYR A HE2  1 
ATOM   3430 H HH   . TYR A 1 225 ? 23.85329  -4.96284  10.48203  1.000 20.58770  ? 217 TYR A HH   1 
ATOM   3431 N N    . LEU A 1 226 ? 15.90831  -3.32098  8.85592   1.000 11.91947  ? 218 LEU A N    1 
ATOM   3432 C CA   . LEU A 1 226 ? 15.57383  -2.33576  7.83873   1.000 8.30983   ? 218 LEU A CA   1 
ATOM   3433 C C    . LEU A 1 226 ? 14.74591  -1.20079  8.42551   1.000 12.09546  ? 218 LEU A C    1 
ATOM   3434 O O    . LEU A 1 226 ? 15.02806  -0.02604  8.18442   1.000 11.82121  ? 218 LEU A O    1 
ATOM   3435 C CB   . LEU A 1 226 ? 14.80386  -3.00392  6.70492   1.000 12.33513  ? 218 LEU A CB   1 
ATOM   3436 C CG   . LEU A 1 226 ? 15.58704  -3.75933  5.63990   1.000 25.38095  ? 218 LEU A CG   1 
ATOM   3437 C CD1  . LEU A 1 226 ? 14.60562  -4.68026  4.87851   1.000 23.85598  ? 218 LEU A CD1  1 
ATOM   3438 C CD2  . LEU A 1 226 ? 16.29559  -2.80713  4.71397   1.000 18.45754  ? 218 LEU A CD2  1 
ATOM   3439 H H    . LEU A 1 226 ? 15.61466  -4.11171  8.68823   1.000 14.32039  ? 218 LEU A H    1 
ATOM   3440 H HA   . LEU A 1 226 ? 16.39728  -1.96629  7.48331   1.000 9.98882   ? 218 LEU A HA   1 
ATOM   3441 H HB2  . LEU A 1 226 ? 14.19259  -3.64297  7.10348   1.000 14.81917  ? 218 LEU A HB2  1 
ATOM   3442 H HB3  . LEU A 1 226 ? 14.30550  -2.31204  6.24249   1.000 14.81917  ? 218 LEU A HB3  1 
ATOM   3443 H HG   . LEU A 1 226 ? 16.27926  -4.30427  6.04583   1.000 30.47416  ? 218 LEU A HG   1 
ATOM   3444 H HD11 . LEU A 1 226 ? 15.05690  -5.05123  4.10416   1.000 28.64420  ? 218 LEU A HD11 1 
ATOM   3445 H HD12 . LEU A 1 226 ? 14.32053  -5.39498  5.46911   1.000 28.64420  ? 218 LEU A HD12 1 
ATOM   3446 H HD13 . LEU A 1 226 ? 13.83811  -4.15883  4.59577   1.000 28.64420  ? 218 LEU A HD13 1 
ATOM   3447 H HD21 . LEU A 1 226 ? 16.77437  -3.31739  4.04218   1.000 22.16607  ? 218 LEU A HD21 1 
ATOM   3448 H HD22 . LEU A 1 226 ? 15.63935  -2.23356  4.28822   1.000 22.16607  ? 218 LEU A HD22 1 
ATOM   3449 H HD23 . LEU A 1 226 ? 16.91898  -2.27116  5.22877   1.000 22.16607  ? 218 LEU A HD23 1 
ATOM   3450 N N    . GLY A 1 227 ? 13.69182  -1.53545  9.17474   1.000 9.88854   ? 219 GLY A N    1 
ATOM   3451 C CA   . GLY A 1 227 ? 12.82901  -0.48943  9.70722   1.000 11.11184  ? 219 GLY A CA   1 
ATOM   3452 C C    . GLY A 1 227 ? 13.57888  0.49057   10.59127  1.000 9.25649   ? 219 GLY A C    1 
ATOM   3453 O O    . GLY A 1 227 ? 13.40966  1.71005   10.48817  1.000 10.70680  ? 219 GLY A O    1 
ATOM   3454 H H    . GLY A 1 227 ? 13.46330  -2.33825  9.38187   1.000 11.88327  ? 219 GLY A H    1 
ATOM   3455 H HA2  . GLY A 1 227 ? 12.43316  0.00436   8.97212   1.000 13.35123  ? 219 GLY A HA2  1 
ATOM   3456 H HA3  . GLY A 1 227 ? 12.12151  -0.89447  10.23284  1.000 13.35123  ? 219 GLY A HA3  1 
ATOM   3457 N N    . ALA A 1 228 ? 14.39198  -0.03363  11.50126  1.000 9.43230   ? 220 ALA A N    1 
ATOM   3458 C CA   . ALA A 1 228 ? 15.14833  0.83043   12.39453  1.000 11.39784  ? 220 ALA A CA   1 
ATOM   3459 C C    . ALA A 1 228 ? 16.11598  1.70254   11.61206  1.000 12.66767  ? 220 ALA A C    1 
ATOM   3460 O O    . ALA A 1 228 ? 16.18342  2.92293   11.81442  1.000 9.58816   ? 220 ALA A O    1 
ATOM   3461 C CB   . ALA A 1 228 ? 15.90194  -0.02054  13.41724  1.000 7.86644   ? 220 ALA A CB   1 
ATOM   3462 H H    . ALA A 1 228 ? 14.52165  -0.87544  11.62014  1.000 11.33579  ? 220 ALA A H    1 
ATOM   3463 H HA   . ALA A 1 228 ? 14.53433  1.41024   12.87173  1.000 13.69443  ? 220 ALA A HA   1 
ATOM   3464 H HB1  . ALA A 1 228 ? 16.38848  0.56514   14.01820  1.000 9.45675   ? 220 ALA A HB1  1 
ATOM   3465 H HB2  . ALA A 1 228 ? 15.26324  -0.55170  13.91807  1.000 9.45675   ? 220 ALA A HB2  1 
ATOM   3466 H HB3  . ALA A 1 228 ? 16.52103  -0.60233  12.94910  1.000 9.45675   ? 220 ALA A HB3  1 
ATOM   3467 N N    . SER A 1 229 ? 16.91358  1.09222   10.73366  1.000 12.01879  ? 221 SER A N    1 
ATOM   3468 C CA   . SER A 1 229 ? 17.92899  1.88717   10.05812  1.000 10.66603  ? 221 SER A CA   1 
ATOM   3469 C C    . SER A 1 229 ? 17.30243  2.91933   9.12779   1.000 10.84457  ? 221 SER A C    1 
ATOM   3470 O O    . SER A 1 229 ? 17.75509  4.07026   9.07510   1.000 14.53011  ? 221 SER A O    1 
ATOM   3471 C CB   . SER A 1 229 ? 18.89393  0.98388   9.29972   1.000 11.13501  ? 221 SER A CB   1 
ATOM   3472 O OG   . SER A 1 229 ? 19.60260  0.21060   10.24504  1.000 11.42576  ? 221 SER A OG   1 
ATOM   3473 H H    . SER A 1 229 ? 16.88629  0.25884   10.52310  1.000 14.43957  ? 221 SER A H    1 
ATOM   3474 H HA   . SER A 1 229 ? 18.44142  2.36611   10.72815  1.000 12.81625  ? 221 SER A HA   1 
ATOM   3475 H HB2  . SER A 1 229 ? 18.39680  0.39963   8.70607   1.000 13.37904  ? 221 SER A HB2  1 
ATOM   3476 H HB3  . SER A 1 229 ? 19.51539  1.52541   8.78841   1.000 13.37904  ? 221 SER A HB3  1 
ATOM   3477 H HG   . SER A 1 229 ? 20.32975  -0.05056  9.91543   1.000 13.72794  ? 221 SER A HG   1 
ATOM   3478 N N    . ILE A 1 230 ? 16.28483  2.52652   8.36209   1.000 9.42546   ? 222 ILE A N    1 
ATOM   3479 C CA   . ILE A 1 230 ? 15.64171  3.48350   7.46899   1.000 9.62956   ? 222 ILE A CA   1 
ATOM   3480 C C    . ILE A 1 230 ? 14.99859  4.61399   8.26686   1.000 13.55910  ? 222 ILE A C    1 
ATOM   3481 O O    . ILE A 1 230 ? 15.08144  5.78825   7.88570   1.000 12.67026  ? 222 ILE A O    1 
ATOM   3482 C CB   . ILE A 1 230 ? 14.60989  2.77655   6.57429   1.000 11.10593  ? 222 ILE A CB   1 
ATOM   3483 C CG1  . ILE A 1 230 ? 15.31616  1.81057   5.62896   1.000 11.89793  ? 222 ILE A CG1  1 
ATOM   3484 C CG2  . ILE A 1 230 ? 13.82422  3.80050   5.77678   1.000 12.47973  ? 222 ILE A CG2  1 
ATOM   3485 C CD1  . ILE A 1 230 ? 14.39635  0.75415   5.04494   1.000 13.96350  ? 222 ILE A CD1  1 
ATOM   3486 H H    . ILE A 1 230 ? 15.95689  1.73175   8.34217   1.000 11.32758  ? 222 ILE A H    1 
ATOM   3487 H HA   . ILE A 1 230 ? 16.32440  3.86787   6.89707   1.000 11.57249  ? 222 ILE A HA   1 
ATOM   3488 H HB   . ILE A 1 230 ? 13.99821  2.27754   7.13798   1.000 13.34414  ? 222 ILE A HB   1 
ATOM   3489 H HG12 . ILE A 1 230 ? 15.69510  2.31485   4.89207   1.000 14.29453  ? 222 ILE A HG12 1 
ATOM   3490 H HG13 . ILE A 1 230 ? 16.02046  1.35492   6.11604   1.000 14.29453  ? 222 ILE A HG13 1 
ATOM   3491 H HG21 . ILE A 1 230 ? 13.27737  3.33885   5.12200   1.000 14.99269  ? 222 ILE A HG21 1 
ATOM   3492 H HG22 . ILE A 1 230 ? 13.25946  4.30633   6.38182   1.000 14.99269  ? 222 ILE A HG22 1 
ATOM   3493 H HG23 . ILE A 1 230 ? 14.44521  4.39574   5.32849   1.000 14.99269  ? 222 ILE A HG23 1 
ATOM   3494 H HD11 . ILE A 1 230 ? 14.90416  0.19455   4.43676   1.000 16.77323  ? 222 ILE A HD11 1 
ATOM   3495 H HD12 . ILE A 1 230 ? 14.03547  0.21574   5.76660   1.000 16.77323  ? 222 ILE A HD12 1 
ATOM   3496 H HD13 . ILE A 1 230 ? 13.67520  1.19267   4.56688   1.000 16.77323  ? 222 ILE A HD13 1 
ATOM   3497 N N    . TYR A 1 231 ? 14.34969  4.28693   9.38861   1.000 12.43343  ? 223 TYR A N    1 
ATOM   3498 C CA   . TYR A 1 231 ? 13.61291  5.31559   10.11788  1.000 9.89553   ? 223 TYR A CA   1 
ATOM   3499 C C    . TYR A 1 231 ? 14.55447  6.25883   10.86881  1.000 12.07913  ? 223 TYR A C    1 
ATOM   3500 O O    . TYR A 1 231 ? 14.45035  7.48548   10.74160  1.000 11.90844  ? 223 TYR A O    1 
ATOM   3501 C CB   . TYR A 1 231 ? 12.61438  4.67244   11.08449  1.000 9.80671   ? 223 TYR A CB   1 
ATOM   3502 C CG   . TYR A 1 231 ? 11.81485  5.66906   11.89876  1.000 9.44238   ? 223 TYR A CG   1 
ATOM   3503 C CD1  . TYR A 1 231 ? 10.82359  6.43809   11.30073  1.000 11.35172  ? 223 TYR A CD1  1 
ATOM   3504 C CD2  . TYR A 1 231 ? 12.04952  5.84209   13.26110  1.000 10.20089  ? 223 TYR A CD2  1 
ATOM   3505 C CE1  . TYR A 1 231 ? 10.09359  7.33932   12.02516  1.000 11.14009  ? 223 TYR A CE1  1 
ATOM   3506 C CE2  . TYR A 1 231 ? 11.30315  6.76188   14.01307  1.000 10.18964  ? 223 TYR A CE2  1 
ATOM   3507 C CZ   . TYR A 1 231 ? 10.33327  7.50280   13.37286  1.000 8.59951   ? 223 TYR A CZ   1 
ATOM   3508 O OH   . TYR A 1 231 ? 9.54246   8.38638   14.07353  1.000 10.90785  ? 223 TYR A OH   1 
ATOM   3509 H H    . TYR A 1 231 ? 14.32244  3.50072   9.73608   1.000 14.93714  ? 223 TYR A H    1 
ATOM   3510 H HA   . TYR A 1 231 ? 13.11350  5.84241   9.47449   1.000 11.89166  ? 223 TYR A HA   1 
ATOM   3511 H HB2  . TYR A 1 231 ? 11.98666  4.13830   10.57307  1.000 11.78507  ? 223 TYR A HB2  1 
ATOM   3512 H HB3  . TYR A 1 231 ? 13.10176  4.10812   11.70491  1.000 11.78507  ? 223 TYR A HB3  1 
ATOM   3513 H HD1  . TYR A 1 231 ? 10.65378  6.33800   10.39186  1.000 13.63909  ? 223 TYR A HD1  1 
ATOM   3514 H HD2  . TYR A 1 231 ? 12.71151  5.33986   13.67876  1.000 12.25809  ? 223 TYR A HD2  1 
ATOM   3515 H HE1  . TYR A 1 231 ? 9.43328   7.84360   11.60731  1.000 13.38513  ? 223 TYR A HE1  1 
ATOM   3516 H HE2  . TYR A 1 231 ? 11.45945  6.86923   14.92353  1.000 12.24460  ? 223 TYR A HE2  1 
ATOM   3517 H HH   . TYR A 1 231 ? 9.71080   8.33363   14.89479  1.000 13.10644  ? 223 TYR A HH   1 
ATOM   3518 N N    . PHE A 1 232 ? 15.44357  5.71074   11.70298  1.000 10.91274  ? 224 PHE A N    1 
ATOM   3519 C CA   . PHE A 1 232 ? 16.24826  6.56304   12.56964  1.000 9.43090   ? 224 PHE A CA   1 
ATOM   3520 C C    . PHE A 1 232 ? 17.31757  7.30548   11.79409  1.000 14.44010  ? 224 PHE A C    1 
ATOM   3521 O O    . PHE A 1 232 ? 17.81211  8.32724   12.28106  1.000 15.30906  ? 224 PHE A O    1 
ATOM   3522 C CB   . PHE A 1 232 ? 16.85501  5.74012   13.70366  1.000 11.67500  ? 224 PHE A CB   1 
ATOM   3523 C CG   . PHE A 1 232 ? 15.83583  5.28030   14.70408  1.000 10.13471  ? 224 PHE A CG   1 
ATOM   3524 C CD1  . PHE A 1 232 ? 15.23385  6.18441   15.55119  1.000 11.35393  ? 224 PHE A CD1  1 
ATOM   3525 C CD2  . PHE A 1 232 ? 15.44441  3.95647   14.76362  1.000 11.00262  ? 224 PHE A CD2  1 
ATOM   3526 C CE1  . PHE A 1 232 ? 14.28968  5.76589   16.46944  1.000 11.98365  ? 224 PHE A CE1  1 
ATOM   3527 C CE2  . PHE A 1 232 ? 14.49489  3.54339   15.66907  1.000 15.33542  ? 224 PHE A CE2  1 
ATOM   3528 C CZ   . PHE A 1 232 ? 13.91990  4.45388   16.51889  1.000 13.34767  ? 224 PHE A CZ   1 
ATOM   3529 H H    . PHE A 1 232 ? 15.59374  4.86762   11.78169  1.000 13.11231  ? 224 PHE A H    1 
ATOM   3530 H HA   . PHE A 1 232 ? 15.67886  7.22974   12.98460  1.000 11.33411  ? 224 PHE A HA   1 
ATOM   3531 H HB2  . PHE A 1 232 ? 17.28219  4.95412   13.32867  1.000 14.02702  ? 224 PHE A HB2  1 
ATOM   3532 H HB3  . PHE A 1 232 ? 17.50962  6.28241   14.17088  1.000 14.02702  ? 224 PHE A HB3  1 
ATOM   3533 H HD1  . PHE A 1 232 ? 15.46476  7.08409   15.50479  1.000 13.64173  ? 224 PHE A HD1  1 
ATOM   3534 H HD2  . PHE A 1 232 ? 15.82742  3.33752   14.18474  1.000 13.22017  ? 224 PHE A HD2  1 
ATOM   3535 H HE1  . PHE A 1 232 ? 13.90617  6.37915   17.05402  1.000 14.39740  ? 224 PHE A HE1  1 
ATOM   3536 H HE2  . PHE A 1 232 ? 14.24329  2.64879   15.70504  1.000 18.41952  ? 224 PHE A HE2  1 
ATOM   3537 H HZ   . PHE A 1 232 ? 13.27646  4.17596   17.13016  1.000 16.03422  ? 224 PHE A HZ   1 
ATOM   3538 N N    . SER A 1 233 ? 17.65589  6.82796   10.59080  1.000 15.04826  ? 225 SER A N    1 
ATOM   3539 C CA   . SER A 1 233 ? 18.55077  7.55859   9.69716   1.000 16.32093  ? 225 SER A CA   1 
ATOM   3540 C C    . SER A 1 233 ? 17.89486  8.79273   9.09609   1.000 16.04904  ? 225 SER A C    1 
ATOM   3541 O O    . SER A 1 233 ? 18.60517  9.67966   8.60089   1.000 19.80685  ? 225 SER A O    1 
ATOM   3542 C CB   . SER A 1 233 ? 19.02758  6.64998   8.55566   1.000 13.11159  ? 225 SER A CB   1 
ATOM   3543 O OG   . SER A 1 233 ? 17.98699  6.32719   7.68670   1.000 19.89243  ? 225 SER A OG   1 
ATOM   3544 H H    . SER A 1 233 ? 17.37824  6.08006   10.26962  1.000 18.07493  ? 225 SER A H    1 
ATOM   3545 H HA   . SER A 1 233 ? 19.32263  7.83819   10.21384  1.000 19.60214  ? 225 SER A HA   1 
ATOM   3546 H HB2  . SER A 1 233 ? 19.71946  7.11183   8.05678   1.000 15.75093  ? 225 SER A HB2  1 
ATOM   3547 H HB3  . SER A 1 233 ? 19.38290  5.83123   8.93553   1.000 15.75093  ? 225 SER A HB3  1 
ATOM   3548 H HG   . SER A 1 233 ? 18.26952  5.82796   7.07307   1.000 23.88793  ? 225 SER A HG   1 
ATOM   3549 N N    . GLY A 1 234 ? 16.56631  8.87596   9.14740   1.000 15.49919  ? 226 GLY A N    1 
ATOM   3550 C CA   . GLY A 1 234 ? 15.81825  9.90693   8.47035   1.000 14.16857  ? 226 GLY A CA   1 
ATOM   3551 C C    . GLY A 1 234 ? 15.46246  9.57049   7.04616   1.000 16.11281  ? 226 GLY A C    1 
ATOM   3552 O O    . GLY A 1 234 ? 14.81244  10.37958  6.38006   1.000 16.36293  ? 226 GLY A O    1 
ATOM   3553 H H    . GLY A 1 234 ? 16.06930  8.32601   9.58343   1.000 18.61605  ? 226 GLY A H    1 
ATOM   3554 H HA2  . GLY A 1 234 ? 14.99357  10.06642  8.95549   1.000 17.01931  ? 226 GLY A HA2  1 
ATOM   3555 H HA3  . GLY A 1 234 ? 16.34328  10.72253  8.46330   1.000 17.01931  ? 226 GLY A HA3  1 
ATOM   3556 N N    . LEU A 1 235 ? 15.83237  8.38147   6.57453   1.000 17.12406  ? 227 LEU A N    1 
ATOM   3557 C CA   . LEU A 1 235 ? 15.68789  8.03403   5.17295   1.000 15.06711  ? 227 LEU A CA   1 
ATOM   3558 C C    . LEU A 1 235 ? 14.25004  7.76687   4.77178   1.000 16.10043  ? 227 LEU A C    1 
ATOM   3559 O O    . LEU A 1 235 ? 13.93910  7.88523   3.58823   1.000 19.24386  ? 227 LEU A O    1 
ATOM   3560 C CB   . LEU A 1 235 ? 16.56214  6.81352   4.87620   1.000 16.38503  ? 227 LEU A CB   1 
ATOM   3561 C CG   . LEU A 1 235 ? 16.84615  6.42997   3.43133   1.000 15.76881  ? 227 LEU A CG   1 
ATOM   3562 C CD1  . LEU A 1 235 ? 17.48272  7.53564   2.64216   1.000 15.92829  ? 227 LEU A CD1  1 
ATOM   3563 C CD2  . LEU A 1 235 ? 17.75493  5.19142   3.41679   1.000 15.63312  ? 227 LEU A CD2  1 
ATOM   3564 H H    . LEU A 1 235 ? 16.17311  7.75412   7.05404   1.000 20.56590  ? 227 LEU A H    1 
ATOM   3565 H HA   . LEU A 1 235 ? 15.99185  8.77596   4.62702   1.000 18.09756  ? 227 LEU A HA   1 
ATOM   3566 H HB2  . LEU A 1 235 ? 17.42503  6.96871   5.29122   1.000 19.67905  ? 227 LEU A HB2  1 
ATOM   3567 H HB3  . LEU A 1 235 ? 16.13212  6.04474   5.28235   1.000 19.67905  ? 227 LEU A HB3  1 
ATOM   3568 H HG   . LEU A 1 235 ? 15.99947  6.24019   2.99772   1.000 18.93959  ? 227 LEU A HG   1 
ATOM   3569 H HD11 . LEU A 1 235 ? 17.32057  7.38358   1.69798   1.000 19.13097  ? 227 LEU A HD11 1 
ATOM   3570 H HD12 . LEU A 1 235 ? 17.09287  8.38165   2.91269   1.000 19.13097  ? 227 LEU A HD12 1 
ATOM   3571 H HD13 . LEU A 1 235 ? 18.43675  7.53996   2.81744   1.000 19.13097  ? 227 LEU A HD13 1 
ATOM   3572 H HD21 . LEU A 1 235 ? 18.03971  5.01936   2.50564   1.000 18.77676  ? 227 LEU A HD21 1 
ATOM   3573 H HD22 . LEU A 1 235 ? 18.52751  5.36000   3.97857   1.000 18.77676  ? 227 LEU A HD22 1 
ATOM   3574 H HD23 . LEU A 1 235 ? 17.25800  4.43110   3.75720   1.000 18.77676  ? 227 LEU A HD23 1 
ATOM   3575 N N    . SER A 1 236 ? 13.36498  7.43134   5.71136   1.000 19.00956  ? 228 SER A N    1 
ATOM   3576 C CA   . SER A 1 236 ? 11.97446  7.19277   5.35342   1.000 14.80244  ? 228 SER A CA   1 
ATOM   3577 C C    . SER A 1 236 ? 11.19958  8.47433   5.05016   1.000 20.53286  ? 228 SER A C    1 
ATOM   3578 O O    . SER A 1 236 ? 10.08767  8.38996   4.51263   1.000 21.70174  ? 228 SER A O    1 
ATOM   3579 C CB   . SER A 1 236 ? 11.26516  6.43821   6.47830   1.000 19.41340  ? 228 SER A CB   1 
ATOM   3580 O OG   . SER A 1 236 ? 11.15078  7.24735   7.63377   1.000 18.17519  ? 228 SER A OG   1 
ATOM   3581 H H    . SER A 1 236 ? 13.54478  7.33796   6.54716   1.000 22.82849  ? 228 SER A H    1 
ATOM   3582 H HA   . SER A 1 236 ? 11.96302  6.64144   4.55542   1.000 17.77995  ? 228 SER A HA   1 
ATOM   3583 H HB2  . SER A 1 236 ? 10.37711  6.18748   6.17929   1.000 23.31311  ? 228 SER A HB2  1 
ATOM   3584 H HB3  . SER A 1 236 ? 11.77760  5.64451   6.69815   1.000 23.31311  ? 228 SER A HB3  1 
ATOM   3585 H HG   . SER A 1 236 ? 11.91408  7.43241   7.93162   1.000 21.82725  ? 228 SER A HG   1 
ATOM   3586 N N    . GLU A 1 237 ? 11.73419  9.64545   5.39751   1.000 17.74041  ? 229 GLU A N    1 
ATOM   3587 C CA   . GLU A 1 237 ? 10.98377  10.88524  5.23139   1.000 17.81202  ? 229 GLU A CA   1 
ATOM   3588 C C    . GLU A 1 237 ? 10.59455  11.08110  3.77085   1.000 15.80511  ? 229 GLU A C    1 
ATOM   3589 O O    . GLU A 1 237 ? 11.45340  11.09448  2.88183   1.000 18.36397  ? 229 GLU A O    1 
ATOM   3590 C CB   . GLU A 1 237 ? 11.80820  12.07266  5.72180   1.000 15.82916  ? 229 GLU A CB   1 
ATOM   3591 C CG   . GLU A 1 237 ? 11.12756  13.42272  5.50354   1.000 24.95319  ? 229 GLU A CG   1 
ATOM   3592 C CD   . GLU A 1 237 ? 11.95224  14.59473  6.02636   1.000 48.54981  ? 229 GLU A CD   1 
ATOM   3593 O OE1  . GLU A 1 237 ? 12.99834  14.36115  6.66276   1.000 38.35971  ? 229 GLU A OE1  1 
ATOM   3594 O OE2  . GLU A 1 237 ? 11.54945  15.75350  5.80370   1.000 43.33782  ? 229 GLU A OE2  1 
ATOM   3595 H H    . GLU A 1 237 ? 12.52168  9.74626   5.72810   1.000 21.30552  ? 229 GLU A H    1 
ATOM   3596 H HA   . GLU A 1 237 ? 10.17415  10.83573  5.76333   1.000 21.39144  ? 229 GLU A HA   1 
ATOM   3597 H HB2  . GLU A 1 237 ? 11.96700  11.97087  6.67328   1.000 19.01201  ? 229 GLU A HB2  1 
ATOM   3598 H HB3  . GLU A 1 237 ? 12.65231  12.08532  5.24407   1.000 19.01201  ? 229 GLU A HB3  1 
ATOM   3599 H HG2  . GLU A 1 237 ? 10.98774  13.55558  4.55291   1.000 29.96086  ? 229 GLU A HG2  1 
ATOM   3600 H HG3  . GLU A 1 237 ? 10.27583  13.42539  5.96771   1.000 29.96086  ? 229 GLU A HG3  1 
ATOM   3601 N N    . GLY A 1 238 ? 9.29489   11.22302  3.52672   1.000 16.65261  ? 230 GLY A N    1 
ATOM   3602 C CA   . GLY A 1 238 ? 8.79926   11.48328  2.19191   1.000 25.30926  ? 230 GLY A CA   1 
ATOM   3603 C C    . GLY A 1 238 ? 8.77276   10.28854  1.26814   1.000 21.62722  ? 230 GLY A C    1 
ATOM   3604 O O    . GLY A 1 238 ? 8.51387   10.46205  0.07124   1.000 17.70070  ? 230 GLY A O    1 
ATOM   3605 H H    . GLY A 1 238 ? 8.67980   11.17158  4.12557   1.000 20.00015  ? 230 GLY A H    1 
ATOM   3606 H HA2  . GLY A 1 238 ? 7.89300   11.82237  2.25979   1.000 30.38814  ? 230 GLY A HA2  1 
ATOM   3607 H HA3  . GLY A 1 238 ? 9.35971   12.16001  1.78102   1.000 30.38814  ? 230 GLY A HA3  1 
ATOM   3608 N N    . ALA A 1 239 ? 9.04143   9.08409   1.77198   1.000 20.08071  ? 231 ALA A N    1 
ATOM   3609 C CA   . ALA A 1 239 ? 8.98771   7.89452   0.92850   1.000 16.09477  ? 231 ALA A CA   1 
ATOM   3610 C C    . ALA A 1 239 ? 7.54403   7.54986   0.58483   1.000 19.54829  ? 231 ALA A C    1 
ATOM   3611 O O    . ALA A 1 239 ? 6.71161   7.37026   1.47904   1.000 23.80943  ? 231 ALA A O    1 
ATOM   3612 C CB   . ALA A 1 239 ? 9.65826   6.71378   1.62751   1.000 18.77721  ? 231 ALA A CB   1 
ATOM   3613 H H    . ALA A 1 239 ? 9.25509   8.93201   2.59102   1.000 24.11388  ? 231 ALA A H    1 
ATOM   3614 H HA   . ALA A 1 239 ? 9.46473   8.07794   0.10406   1.000 19.33074  ? 231 ALA A HA   1 
ATOM   3615 H HB1  . ALA A 1 239 ? 9.63046   5.94204   1.04054   1.000 22.54968  ? 231 ALA A HB1  1 
ATOM   3616 H HB2  . ALA A 1 239 ? 10.57906  6.94560   1.82574   1.000 22.54968  ? 231 ALA A HB2  1 
ATOM   3617 H HB3  . ALA A 1 239 ? 9.18123   6.52125   2.44987   1.000 22.54968  ? 231 ALA A HB3  1 
ATOM   3618 N N    . SER A 1 240 ? 7.25066   7.44495   -0.71220  1.000 16.03567  ? 232 SER A N    1 
ATOM   3619 C CA   . SER A 1 240 ? 5.92506   7.04703   -1.16269  1.000 14.10253  ? 232 SER A CA   1 
ATOM   3620 C C    . SER A 1 240 ? 5.82978   5.55691   -1.42943  1.000 13.39847  ? 232 SER A C    1 
ATOM   3621 O O    . SER A 1 240 ? 4.76227   4.96417   -1.24017  1.000 16.40700  ? 232 SER A O    1 
ATOM   3622 C CB   . SER A 1 240 ? 5.54998   7.81311   -2.43843  1.000 22.11380  ? 232 SER A CB   1 
ATOM   3623 O OG   . SER A 1 240 ? 5.44228   9.20523   -2.18033  1.000 26.42511  ? 232 SER A OG   1 
ATOM   3624 H H    . SER A 1 240 ? 7.80629   7.60011   -1.35001  1.000 19.25983  ? 232 SER A H    1 
ATOM   3625 H HA   . SER A 1 240 ? 5.27842   7.27465   -0.47643  1.000 16.94006  ? 232 SER A HA   1 
ATOM   3626 H HB2  . SER A 1 240 ? 6.23770   7.66846   -3.10701  1.000 26.55358  ? 232 SER A HB2  1 
ATOM   3627 H HB3  . SER A 1 240 ? 4.69687   7.48562   -2.76378  1.000 26.55358  ? 232 SER A HB3  1 
ATOM   3628 H HG   . SER A 1 240 ? 6.20330   9.53050   -2.03664  1.000 31.72715  ? 232 SER A HG   1 
ATOM   3629 N N    . PHE A 1 241 ? 6.91026   4.94333   -1.88667  1.000 13.16416  ? 233 PHE A N    1 
ATOM   3630 C CA   . PHE A 1 241 ? 6.87893   3.56023   -2.32816  1.000 11.86312  ? 233 PHE A CA   1 
ATOM   3631 C C    . PHE A 1 241 ? 8.06304   2.77951   -1.77526  1.000 14.21041  ? 233 PHE A C    1 
ATOM   3632 O O    . PHE A 1 241 ? 9.16997   3.30717   -1.63750  1.000 13.13247  ? 233 PHE A O    1 
ATOM   3633 C CB   . PHE A 1 241 ? 6.92541   3.46624   -3.86453  1.000 15.99850  ? 233 PHE A CB   1 
ATOM   3634 C CG   . PHE A 1 241 ? 5.73367   4.06333   -4.55136  1.000 18.41668  ? 233 PHE A CG   1 
ATOM   3635 C CD1  . PHE A 1 241 ? 4.48490   3.47185   -4.43222  1.000 21.46029  ? 233 PHE A CD1  1 
ATOM   3636 C CD2  . PHE A 1 241 ? 5.86182   5.20642   -5.31285  1.000 19.02134  ? 233 PHE A CD2  1 
ATOM   3637 C CE1  . PHE A 1 241 ? 3.37740   4.02590   -5.06218  1.000 26.49653  ? 233 PHE A CE1  1 
ATOM   3638 C CE2  . PHE A 1 241 ? 4.76075   5.76259   -5.94320  1.000 23.07556  ? 233 PHE A CE2  1 
ATOM   3639 C CZ   . PHE A 1 241 ? 3.51974   5.15309   -5.82228  1.000 23.50582  ? 233 PHE A CZ   1 
ATOM   3640 H H    . PHE A 1 241 ? 7.68396   5.31319   -1.95139  1.000 15.81401  ? 233 PHE A H    1 
ATOM   3641 H HA   . PHE A 1 241 ? 6.06386   3.15598   -1.99179  1.000 14.25277  ? 233 PHE A HA   1 
ATOM   3642 H HB2  . PHE A 1 241 ? 7.71326   3.93559   -4.18060  1.000 19.21523  ? 233 PHE A HB2  1 
ATOM   3643 H HB3  . PHE A 1 241 ? 6.97286   2.53089   -4.11706  1.000 19.21523  ? 233 PHE A HB3  1 
ATOM   3644 H HD1  . PHE A 1 241 ? 4.38799   2.69759   -3.92622  1.000 25.76937  ? 233 PHE A HD1  1 
ATOM   3645 H HD2  . PHE A 1 241 ? 6.69582   5.60773   -5.40397  1.000 22.84263  ? 233 PHE A HD2  1 
ATOM   3646 H HE1  . PHE A 1 241 ? 2.54095   3.63069   -4.96692  1.000 31.81286  ? 233 PHE A HE1  1 
ATOM   3647 H HE2  . PHE A 1 241 ? 4.85265   6.54033   -6.44478  1.000 27.70769  ? 233 PHE A HE2  1 
ATOM   3648 H HZ   . PHE A 1 241 ? 2.78227   5.51287   -6.26000  1.000 28.22400  ? 233 PHE A HZ   1 
ATOM   3649 N N    . ILE A 1 242 ? 7.82574   1.49946   -1.50234  1.000 13.93886  ? 234 ILE A N    1 
ATOM   3650 C CA   . ILE A 1 242 ? 8.87811   0.52571   -1.24301  1.000 8.92074   ? 234 ILE A CA   1 
ATOM   3651 C C    . ILE A 1 242 ? 8.71720   -0.59236  -2.26338  1.000 10.54084  ? 234 ILE A C    1 
ATOM   3652 O O    . ILE A 1 242 ? 7.59368   -0.98814  -2.57714  1.000 13.35183  ? 234 ILE A O    1 
ATOM   3653 C CB   . ILE A 1 242 ? 8.81802   -0.04100  0.18697   1.000 15.87724  ? 234 ILE A CB   1 
ATOM   3654 C CG1  . ILE A 1 242 ? 8.91653   1.08503   1.21006   1.000 31.83952  ? 234 ILE A CG1  1 
ATOM   3655 C CG2  . ILE A 1 242 ? 9.95086   -1.05112  0.36946   1.000 18.29414  ? 234 ILE A CG2  1 
ATOM   3656 C CD1  . ILE A 1 242 ? 8.57247   0.64752   2.63086   1.000 43.77495  ? 234 ILE A CD1  1 
ATOM   3657 H H    . ILE A 1 242 ? 7.03590   1.16178   -1.46086  1.000 16.74365  ? 234 ILE A H    1 
ATOM   3658 H HA   . ILE A 1 242 ? 9.74382   0.94970   -1.35098  1.000 10.72191  ? 234 ILE A HA   1 
ATOM   3659 H HB   . ILE A 1 242 ? 7.96793   -0.48768  0.32383   1.000 19.06971  ? 234 ILE A HB   1 
ATOM   3660 H HG12 . ILE A 1 242 ? 9.82522   1.42438   1.21540   1.000 38.22444  ? 234 ILE A HG12 1 
ATOM   3661 H HG13 . ILE A 1 242 ? 8.30030   1.79079   0.95896   1.000 38.22444  ? 234 ILE A HG13 1 
ATOM   3662 H HG21 . ILE A 1 242 ? 9.92327   -1.39630  1.27554   1.000 21.97000  ? 234 ILE A HG21 1 
ATOM   3663 H HG22 . ILE A 1 242 ? 9.83287   -1.77587  -0.26435  1.000 21.97000  ? 234 ILE A HG22 1 
ATOM   3664 H HG23 . ILE A 1 242 ? 10.79850  -0.60719  0.21028   1.000 21.97000  ? 234 ILE A HG23 1 
ATOM   3665 H HD11 . ILE A 1 242 ? 8.54214   1.42981   3.20358   1.000 52.54696  ? 234 ILE A HD11 1 
ATOM   3666 H HD12 . ILE A 1 242 ? 7.70782   0.20793   2.62528   1.000 52.54696  ? 234 ILE A HD12 1 
ATOM   3667 H HD13 . ILE A 1 242 ? 9.25385   0.03319   2.94586   1.000 52.54696  ? 234 ILE A HD13 1 
ATOM   3668 N N    . THR A 1 243 ? 9.82640   -1.10203  -2.78959  1.000 9.61569   ? 235 THR A N    1 
ATOM   3669 C CA   . THR A 1 243 ? 9.72527   -2.19830  -3.73833  1.000 8.68964   ? 235 THR A CA   1 
ATOM   3670 C C    . THR A 1 243 ? 10.96511  -3.05993  -3.60266  1.000 14.46829  ? 235 THR A C    1 
ATOM   3671 O O    . THR A 1 243 ? 11.96248  -2.65178  -3.00632  1.000 13.27652  ? 235 THR A O    1 
ATOM   3672 C CB   . THR A 1 243 ? 9.54889   -1.70174  -5.17871  1.000 13.32109  ? 235 THR A CB   1 
ATOM   3673 O OG1  . THR A 1 243 ? 9.18171   -2.80940  -6.01203  1.000 15.43846  ? 235 THR A OG1  1 
ATOM   3674 C CG2  . THR A 1 243 ? 10.81786  -1.10578  -5.69725  1.000 13.67372  ? 235 THR A CG2  1 
ATOM   3675 H H    . THR A 1 243 ? 10.62563  -0.83594  -2.61633  1.000 11.55585  ? 235 THR A H    1 
ATOM   3676 H HA   . THR A 1 243 ? 8.95007   -2.74193  -3.52755  1.000 10.44460  ? 235 THR A HA   1 
ATOM   3677 H HB   . THR A 1 243 ? 8.86051   -1.01879  -5.20337  1.000 16.00233  ? 235 THR A HB   1 
ATOM   3678 H HG1  . THR A 1 243 ? 8.45456   -3.13786  -5.74940  1.000 18.54317  ? 235 THR A HG1  1 
ATOM   3679 H HG21 . THR A 1 243 ? 10.64862  -0.63775  -6.52984  1.000 16.42549  ? 235 THR A HG21 1 
ATOM   3680 H HG22 . THR A 1 243 ? 11.17807  -0.47842  -5.05106  1.000 16.42549  ? 235 THR A HG22 1 
ATOM   3681 H HG23 . THR A 1 243 ? 11.47181  -1.80435  -5.85613  1.000 16.42549  ? 235 THR A HG23 1 
ATOM   3682 N N    . THR A 1 244 ? 10.86041  -4.27856  -4.11362  1.000 11.54785  ? 236 THR A N    1 
ATOM   3683 C CA   . THR A 1 244 ? 11.96390  -5.20730  -4.26770  1.000 10.19208  ? 236 THR A CA   1 
ATOM   3684 C C    . THR A 1 244 ? 12.30593  -5.36599  -5.74318  1.000 13.78478  ? 236 THR A C    1 
ATOM   3685 O O    . THR A 1 244 ? 11.50804  -5.04773  -6.62631  1.000 16.73384  ? 236 THR A O    1 
ATOM   3686 C CB   . THR A 1 244 ? 11.59140  -6.57207  -3.67928  1.000 20.12599  ? 236 THR A CB   1 
ATOM   3687 O OG1  . THR A 1 244 ? 10.23633  -6.88832  -4.04305  1.000 28.49445  ? 236 THR A OG1  1 
ATOM   3688 C CG2  . THR A 1 244 ? 11.67200  -6.53575  -2.15857  1.000 16.69697  ? 236 THR A CG2  1 
ATOM   3689 H H    . THR A 1 244 ? 10.11634  -4.60661  -4.39354  1.000 13.87444  ? 236 THR A H    1 
ATOM   3690 H HA   . THR A 1 244 ? 12.74683  -4.86881  -3.80581  1.000 12.24752  ? 236 THR A HA   1 
ATOM   3691 H HB   . THR A 1 244 ? 12.20279  -7.24545  -4.01641  1.000 24.16821  ? 236 THR A HB   1 
ATOM   3692 H HG1  . THR A 1 244 ? 9.93292   -7.48225  -3.53238  1.000 34.21036  ? 236 THR A HG1  1 
ATOM   3693 H HG21 . THR A 1 244 ? 12.19580  -7.28578  -1.83610  1.000 20.05339  ? 236 THR A HG21 1 
ATOM   3694 H HG22 . THR A 1 244 ? 12.09154  -5.71078  -1.86819  1.000 20.05339  ? 236 THR A HG22 1 
ATOM   3695 H HG23 . THR A 1 244 ? 10.78132  -6.58695  -1.77782  1.000 20.05339  ? 236 THR A HG23 1 
ATOM   3696 N N    . TYR A 1 245 ? 13.50606  -5.86886  -6.00237  1.000 15.91850  ? 237 TYR A N    1 
ATOM   3697 C CA   . TYR A 1 245 ? 13.94061  -6.17250  -7.35691  1.000 16.05838  ? 237 TYR A CA   1 
ATOM   3698 C C    . TYR A 1 245 ? 13.52576  -7.60693  -7.67644  1.000 20.63578  ? 237 TYR A C    1 
ATOM   3699 O O    . TYR A 1 245 ? 12.77144  -8.23294  -6.92807  1.000 25.88841  ? 237 TYR A O    1 
ATOM   3700 C CB   . TYR A 1 245 ? 15.44301  -5.94193  -7.48582  1.000 16.70585  ? 237 TYR A CB   1 
ATOM   3701 C CG   . TYR A 1 245 ? 15.96864  -5.86976  -8.90286  1.000 17.11489  ? 237 TYR A CG   1 
ATOM   3702 C CD1  . TYR A 1 245 ? 15.43388  -4.98416  -9.83160  1.000 16.00388  ? 237 TYR A CD1  1 
ATOM   3703 C CD2  . TYR A 1 245 ? 16.99817  -6.69660  -9.31337  1.000 14.52382  ? 237 TYR A CD2  1 
ATOM   3704 C CE1  . TYR A 1 245 ? 15.93180  -4.92370  -11.12967 1.000 11.66638  ? 237 TYR A CE1  1 
ATOM   3705 C CE2  . TYR A 1 245 ? 17.48746  -6.65068  -10.61219 1.000 13.70301  ? 237 TYR A CE2  1 
ATOM   3706 C CZ   . TYR A 1 245 ? 16.96409  -5.76145  -11.50202 1.000 11.54523  ? 237 TYR A CZ   1 
ATOM   3707 O OH   . TYR A 1 245 ? 17.47070  -5.71761  -12.78108 1.000 15.60418  ? 237 TYR A OH   1 
ATOM   3708 H H    . TYR A 1 245 ? 14.09500  -6.04539  -5.40105  1.000 19.11922  ? 237 TYR A H    1 
ATOM   3709 H HA   . TYR A 1 245 ? 13.50396  -5.57651  -7.98543  1.000 19.28708  ? 237 TYR A HA   1 
ATOM   3710 H HB2  . TYR A 1 245 ? 15.66144  -5.10166  -7.05324  1.000 20.06404  ? 237 TYR A HB2  1 
ATOM   3711 H HB3  . TYR A 1 245 ? 15.90331  -6.67227  -7.04352  1.000 20.06404  ? 237 TYR A HB3  1 
ATOM   3712 H HD1  . TYR A 1 245 ? 14.73411  -4.42474  -9.58207  1.000 19.22167  ? 237 TYR A HD1  1 
ATOM   3713 H HD2  . TYR A 1 245 ? 17.37050  -7.29568  -8.70727  1.000 17.44561  ? 237 TYR A HD2  1 
ATOM   3714 H HE1  . TYR A 1 245 ? 15.57180  -4.32331  -11.74191 1.000 14.01668  ? 237 TYR A HE1  1 
ATOM   3715 H HE2  . TYR A 1 245 ? 18.17037  -7.22519  -10.87388 1.000 16.46064  ? 237 TYR A HE2  1 
ATOM   3716 H HH   . TYR A 1 245 ? 18.06600  -6.30283  -12.87452 1.000 18.74204  ? 237 TYR A HH   1 
ATOM   3717 N N    . VAL A 1 246 ? 14.00369  -8.14217  -8.79303  1.000 14.28993  ? 238 VAL A N    1 
ATOM   3718 C CA   . VAL A 1 246 ? 13.59110  -9.45852  -9.26216  1.000 12.44899  ? 238 VAL A CA   1 
ATOM   3719 C C    . VAL A 1 246 ? 14.80483  -10.36299 -9.36594  1.000 17.31114  ? 238 VAL A C    1 
ATOM   3720 O O    . VAL A 1 246 ? 15.90453  -9.91699  -9.70964  1.000 14.27050  ? 238 VAL A O    1 
ATOM   3721 C CB   . VAL A 1 246 ? 12.88161  -9.39155  -10.63263 1.000 19.76557  ? 238 VAL A CB   1 
ATOM   3722 C CG1  . VAL A 1 246 ? 11.44275  -8.96477  -10.47384 1.000 22.62002  ? 238 VAL A CG1  1 
ATOM   3723 C CG2  . VAL A 1 246 ? 13.61686  -8.44053  -11.58505 1.000 17.91910  ? 238 VAL A CG2  1 
ATOM   3724 H H    . VAL A 1 246 ? 14.57732  -7.75585  -9.30421  1.000 17.16494  ? 238 VAL A H    1 
ATOM   3725 H HA   . VAL A 1 246 ? 12.98097  -9.83156  -8.60682  1.000 14.95581  ? 238 VAL A HA   1 
ATOM   3726 H HB   . VAL A 1 246 ? 12.89354  -10.27956 -11.02275 1.000 23.73570  ? 238 VAL A HB   1 
ATOM   3727 H HG11 . VAL A 1 246 ? 11.01249  -8.97519  -11.34314 1.000 27.16104  ? 238 VAL A HG11 1 
ATOM   3728 H HG12 . VAL A 1 246 ? 10.99431  -9.58255  -9.87538  1.000 27.16104  ? 238 VAL A HG12 1 
ATOM   3729 H HG13 . VAL A 1 246 ? 11.41819  -8.06865  -10.10333 1.000 27.16104  ? 238 VAL A HG13 1 
ATOM   3730 H HG21 . VAL A 1 246 ? 13.21005  -8.49680  -12.46382 1.000 21.51995  ? 238 VAL A HG21 1 
ATOM   3731 H HG22 . VAL A 1 246 ? 13.54519  -7.53502  -11.24474 1.000 21.51995  ? 238 VAL A HG22 1 
ATOM   3732 H HG23 . VAL A 1 246 ? 14.54954  -8.70229  -11.63495 1.000 21.51995  ? 238 VAL A HG23 1 
ATOM   3733 N N    . GLY A 1 247 ? 14.58943  -11.64702 -9.08635  1.000 15.09069  ? 239 GLY A N    1 
ATOM   3734 C CA   . GLY A 1 247 ? 15.59730  -12.65050 -9.34082  1.000 16.23615  ? 239 GLY A CA   1 
ATOM   3735 C C    . GLY A 1 247 ? 15.89336  -12.80810 -10.81678 1.000 12.61393  ? 239 GLY A C    1 
ATOM   3736 O O    . GLY A 1 247 ? 15.16286  -12.33817 -11.68812 1.000 14.40714  ? 239 GLY A O    1 
ATOM   3737 H H    . GLY A 1 247 ? 13.86223  -11.95666 -8.74740  1.000 18.12585  ? 239 GLY A H    1 
ATOM   3738 H HA2  . GLY A 1 247 ? 16.41894  -12.40224 -8.88896  1.000 19.50040  ? 239 GLY A HA2  1 
ATOM   3739 H HA3  . GLY A 1 247 ? 15.29358  -13.50513 -8.99692  1.000 19.50040  ? 239 GLY A HA3  1 
ATOM   3740 N N    . HIS A 1 248 ? 16.99323  -13.51507 -11.10061 1.000 15.83833  ? 240 HIS A N    1 
ATOM   3741 C CA   . HIS A 1 248 ? 17.45671  -13.63731 -12.47914 1.000 15.03155  ? 240 HIS A CA   1 
ATOM   3742 C C    . HIS A 1 248 ? 16.58284  -14.55801 -13.33478 1.000 14.91423  ? 240 HIS A C    1 
ATOM   3743 O O    . HIS A 1 248 ? 16.58276  -14.42196 -14.56158 1.000 17.77219  ? 240 HIS A O    1 
ATOM   3744 C CB   . HIS A 1 248 ? 18.89921  -14.15451 -12.50454 1.000 22.77234  ? 240 HIS A CB   1 
ATOM   3745 C CG   . HIS A 1 248 ? 19.02486  -15.60700 -12.14828 1.000 23.98627  ? 240 HIS A CG   1 
ATOM   3746 N ND1  . HIS A 1 248 ? 19.08959  -16.05027 -10.84480 1.000 32.17844  ? 240 HIS A ND1  1 
ATOM   3747 C CD2  . HIS A 1 248 ? 19.08905  -16.71604 -12.92438 1.000 32.54491  ? 240 HIS A CD2  1 
ATOM   3748 C CE1  . HIS A 1 248 ? 19.18700  -17.36812 -10.83232 1.000 34.77807  ? 240 HIS A CE1  1 
ATOM   3749 N NE2  . HIS A 1 248 ? 19.18610  -17.79727 -12.08129 1.000 45.62199  ? 240 HIS A NE2  1 
ATOM   3750 H H    . HIS A 1 248 ? 17.47820  -13.92517 -10.52077 1.000 19.02302  ? 240 HIS A H    1 
ATOM   3751 H HA   . HIS A 1 248 ? 17.43092  -12.75281 -12.87651 1.000 18.05489  ? 240 HIS A HA   1 
ATOM   3752 H HB2  . HIS A 1 248 ? 19.25755  -14.03641 -13.39816 1.000 27.34383  ? 240 HIS A HB2  1 
ATOM   3753 H HB3  . HIS A 1 248 ? 19.42437  -13.64634 -11.86668 1.000 27.34383  ? 240 HIS A HB3  1 
ATOM   3754 H HD2  . HIS A 1 248 ? 19.07085  -16.74093 -13.85387 1.000 39.07091  ? 240 HIS A HD2  1 
ATOM   3755 H HE1  . HIS A 1 248 ? 19.24612  -17.90231 -10.07334 1.000 41.75071  ? 240 HIS A HE1  1 
ATOM   3756 N N    . ASN A 1 249 ? 15.83555  -15.47360 -12.73020 1.000 16.40143  ? 241 ASN A N    1 
ATOM   3757 C CA   . ASN A 1 249 ? 15.08534  -16.47896 -13.48522 1.000 18.02413  ? 241 ASN A CA   1 
ATOM   3758 C C    . ASN A 1 249 ? 13.65778  -15.99351 -13.72442 1.000 15.53819  ? 241 ASN A C    1 
ATOM   3759 O O    . ASN A 1 249 ? 12.90752  -15.76611 -12.77464 1.000 15.46596  ? 241 ASN A O    1 
ATOM   3760 C CB   . ASN A 1 249 ? 15.08446  -17.81511 -12.74122 1.000 18.55215  ? 241 ASN A CB   1 
ATOM   3761 C CG   . ASN A 1 249 ? 14.36734  -18.92107 -13.51703 1.000 18.93391  ? 241 ASN A CG   1 
ATOM   3762 O OD1  . ASN A 1 249 ? 13.86797  -18.70841 -14.61194 1.000 21.93655  ? 241 ASN A OD1  1 
ATOM   3763 N ND2  . ASN A 1 249 ? 14.31439  -20.10383 -12.93412 1.000 39.64921  ? 241 ASN A ND2  1 
ATOM   3764 H H    . ASN A 1 249 ? 15.74402  -15.53648 -11.87740 1.000 19.69874  ? 241 ASN A H    1 
ATOM   3765 H HA   . ASN A 1 249 ? 15.50565  -16.60572 -14.35019 1.000 21.64598  ? 241 ASN A HA   1 
ATOM   3766 H HB2  . ASN A 1 249 ? 16.00115  -18.09661 -12.59515 1.000 22.27960  ? 241 ASN A HB2  1 
ATOM   3767 H HB3  . ASN A 1 249 ? 14.63218  -17.70330 -11.89043 1.000 22.27960  ? 241 ASN A HB3  1 
ATOM   3768 H HD21 . ASN A 1 249 ? 14.67186  -20.21826 -12.16035 1.000 47.59608  ? 241 ASN A HD21 1 
ATOM   3769 H HD22 . ASN A 1 249 ? 13.92242  -20.76018 -13.32802 1.000 47.59608  ? 241 ASN A HD22 1 
ATOM   3770 N N    . ALA A 1 250 ? 13.29841  -15.80634 -14.99581 1.000 14.81002  ? 242 ALA A N    1 
ATOM   3771 C CA   . ALA A 1 250 ? 11.96397  -15.33794 -15.34209 1.000 13.01272  ? 242 ALA A CA   1 
ATOM   3772 C C    . ALA A 1 250 ? 10.88222  -16.31603 -14.90567 1.000 9.51626   ? 242 ALA A C    1 
ATOM   3773 O O    . ALA A 1 250 ? 9.72288   -15.91110 -14.73808 1.000 13.23579  ? 242 ALA A O    1 
ATOM   3774 C CB   . ALA A 1 250 ? 11.87919  -15.10476 -16.85235 1.000 15.31492  ? 242 ALA A CB   1 
ATOM   3775 H H    . ALA A 1 250 ? 13.81004  -15.94396 -15.67323 1.000 17.78905  ? 242 ALA A H    1 
ATOM   3776 H HA   . ALA A 1 250 ? 11.79790  -14.49398 -14.89372 1.000 15.63229  ? 242 ALA A HA   1 
ATOM   3777 H HB1  . ALA A 1 250 ? 10.98646  -14.79744 -17.07482 1.000 18.39493  ? 242 ALA A HB1  1 
ATOM   3778 H HB2  . ALA A 1 250 ? 12.53258  -14.43402 -17.10550 1.000 18.39493  ? 242 ALA A HB2  1 
ATOM   3779 H HB3  . ALA A 1 250 ? 12.06604  -15.93847 -17.31160 1.000 18.39493  ? 242 ALA A HB3  1 
ATOM   3780 N N    . GLU A 1 251 ? 11.23315  -17.58958 -14.70289 1.000 14.73273  ? 243 GLU A N    1 
ATOM   3781 C CA   . GLU A 1 251 ? 10.23899  -18.55470 -14.25873 1.000 11.85651  ? 243 GLU A CA   1 
ATOM   3782 C C    . GLU A 1 251 ? 10.00748  -18.49106 -12.75553 1.000 16.66782  ? 243 GLU A C    1 
ATOM   3783 O O    . GLU A 1 251 ? 9.04271   -19.09154 -12.27366 1.000 17.76165  ? 243 GLU A O    1 
ATOM   3784 C CB   . GLU A 1 251 ? 10.65440  -19.96424 -14.67341 1.000 13.67741  ? 243 GLU A CB   1 
ATOM   3785 C CG   . GLU A 1 251 ? 10.90855  -20.12131 -16.17035 1.000 14.12955  ? 243 GLU A CG   1 
ATOM   3786 C CD   . GLU A 1 251 ? 9.67027   -19.96573 -17.03083 1.000 23.68898  ? 243 GLU A CD   1 
ATOM   3787 O OE1  . GLU A 1 251 ? 8.52522   -20.08547 -16.53342 1.000 18.55846  ? 243 GLU A OE1  1 
ATOM   3788 O OE2  . GLU A 1 251 ? 9.84394   -19.73181 -18.24387 1.000 23.67287  ? 243 GLU A OE2  1 
ATOM   3789 H H    . GLU A 1 251 ? 12.02452  -17.90715 -14.81458 1.000 17.69629  ? 243 GLU A H    1 
ATOM   3790 H HA   . GLU A 1 251 ? 9.39307   -18.36884 -14.69551 1.000 14.24484  ? 243 GLU A HA   1 
ATOM   3791 H HB2  . GLU A 1 251 ? 11.47382  -20.19613 -14.20900 1.000 16.42991  ? 243 GLU A HB2  1 
ATOM   3792 H HB3  . GLU A 1 251 ? 9.94770   -20.58156 -14.42767 1.000 16.42991  ? 243 GLU A HB3  1 
ATOM   3793 H HG2  . GLU A 1 251 ? 11.54687  -19.44635 -16.44942 1.000 16.97249  ? 243 GLU A HG2  1 
ATOM   3794 H HG3  . GLU A 1 251 ? 11.26973  -21.00680 -16.33273 1.000 16.97249  ? 243 GLU A HG3  1 
ATOM   3795 N N    . ASP A 1 252 ? 10.84645  -17.74641 -12.00376 1.000 16.24912  ? 244 ASP A N    1 
ATOM   3796 C CA   . ASP A 1 252 ? 10.72655  -17.70152 -10.54875 1.000 18.20756  ? 244 ASP A CA   1 
ATOM   3797 C C    . ASP A 1 252 ? 11.39479  -16.43066 -10.04167 1.000 17.18402  ? 244 ASP A C    1 
ATOM   3798 O O    . ASP A 1 252 ? 12.41654  -16.49446 -9.34520  1.000 18.31196  ? 244 ASP A O    1 
ATOM   3799 C CB   . ASP A 1 252 ? 11.36887  -18.92735 -9.90244  1.000 27.01103  ? 244 ASP A CB   1 
ATOM   3800 C CG   . ASP A 1 252 ? 10.93644  -19.12457 -8.46367  1.000 31.86121  ? 244 ASP A CG   1 
ATOM   3801 O OD1  . ASP A 1 252 ? 10.07829  -18.36066 -7.97679  1.000 31.46407  ? 244 ASP A OD1  1 
ATOM   3802 O OD2  . ASP A 1 252 ? 11.45882  -20.05895 -7.82307  1.000 39.74085  ? 244 ASP A OD2  1 
ATOM   3803 H H    . ASP A 1 252 ? 11.48537  -17.26540 -12.32000 1.000 19.51597  ? 244 ASP A H    1 
ATOM   3804 H HA   . ASP A 1 252 ? 9.78907   -17.69687 -10.29973 1.000 21.86609  ? 244 ASP A HA   1 
ATOM   3805 H HB2  . ASP A 1 252 ? 11.11509  -19.71839 -10.40319 1.000 32.43026  ? 244 ASP A HB2  1 
ATOM   3806 H HB3  . ASP A 1 252 ? 12.33310  -18.82238 -9.91428  1.000 32.43026  ? 244 ASP A HB3  1 
ATOM   3807 N N    . PRO A 1 253 ? 10.86915  -15.25762 -10.38477 1.000 14.53924  ? 245 PRO A N    1 
ATOM   3808 C CA   . PRO A 1 253 ? 11.61465  -14.02488 -10.12312 1.000 12.33305  ? 245 PRO A CA   1 
ATOM   3809 C C    . PRO A 1 253 ? 11.33307  -13.38315 -8.78217  1.000 13.03466  ? 245 PRO A C    1 
ATOM   3810 O O    . PRO A 1 253 ? 12.00219  -12.38830 -8.46290  1.000 15.04626  ? 245 PRO A O    1 
ATOM   3811 C CB   . PRO A 1 253 ? 11.16832  -13.10033 -11.26615 1.000 16.03035  ? 245 PRO A CB   1 
ATOM   3812 C CG   . PRO A 1 253 ? 9.86185   -13.62418 -11.73240 1.000 19.91891  ? 245 PRO A CG   1 
ATOM   3813 C CD   . PRO A 1 253 ? 9.62848   -14.99651 -11.13437 1.000 21.38082  ? 245 PRO A CD   1 
ATOM   3814 H HA   . PRO A 1 253 ? 12.56695  -14.19070 -10.20388 1.000 14.81668  ? 245 PRO A HA   1 
ATOM   3815 H HB2  . PRO A 1 253 ? 11.07573  -12.19358 -10.93429 1.000 19.25344  ? 245 PRO A HB2  1 
ATOM   3816 H HB3  . PRO A 1 253 ? 11.82343  -13.12670 -11.98102 1.000 19.25344  ? 245 PRO A HB3  1 
ATOM   3817 H HG2  . PRO A 1 253 ? 9.16166   -13.01620 -11.44778 1.000 23.91972  ? 245 PRO A HG2  1 
ATOM   3818 H HG3  . PRO A 1 253 ? 9.87632   -13.68362 -12.70046 1.000 23.91972  ? 245 PRO A HG3  1 
ATOM   3819 H HD2  . PRO A 1 253 ? 8.86188   -14.98789 -10.54011 1.000 25.67401  ? 245 PRO A HD2  1 
ATOM   3820 H HD3  . PRO A 1 253 ? 9.50066   -15.65912 -11.83116 1.000 25.67401  ? 245 PRO A HD3  1 
ATOM   3821 N N    . TYR A 1 254 ? 10.36478  -13.89214 -8.00953  1.000 16.42065  ? 246 TYR A N    1 
ATOM   3822 C CA   . TYR A 1 254 ? 9.91044   -13.19687 -6.80747  1.000 14.03812  ? 246 TYR A CA   1 
ATOM   3823 C C    . TYR A 1 254 ? 10.15400  -14.01410 -5.54315  1.000 11.69011  ? 246 TYR A C    1 
ATOM   3824 O O    . TYR A 1 254 ? 9.39411   -13.92690 -4.58385  1.000 15.45232  ? 246 TYR A O    1 
ATOM   3825 C CB   . TYR A 1 254 ? 8.43126   -12.81596 -6.90359  1.000 15.49792  ? 246 TYR A CB   1 
ATOM   3826 C CG   . TYR A 1 254 ? 8.10516   -11.90337 -8.05992  1.000 12.16041  ? 246 TYR A CG   1 
ATOM   3827 C CD1  . TYR A 1 254 ? 8.61643   -10.61404 -8.11745  1.000 13.67732  ? 246 TYR A CD1  1 
ATOM   3828 C CD2  . TYR A 1 254 ? 7.33320   -12.34596 -9.11847  1.000 22.67016  ? 246 TYR A CD2  1 
ATOM   3829 C CE1  . TYR A 1 254 ? 8.33966   -9.78590  -9.17827  1.000 15.15653  ? 246 TYR A CE1  1 
ATOM   3830 C CE2  . TYR A 1 254 ? 7.04912   -11.51717 -10.18992 1.000 18.44850  ? 246 TYR A CE2  1 
ATOM   3831 C CZ   . TYR A 1 254 ? 7.55900   -10.23939 -10.21276 1.000 16.77941  ? 246 TYR A CZ   1 
ATOM   3832 O OH   . TYR A 1 254 ? 7.27553   -9.40415  -11.26793 1.000 18.02361  ? 246 TYR A OH   1 
ATOM   3833 H H    . TYR A 1 254 ? 9.96063   -14.63536 -8.16409  1.000 19.72180  ? 246 TYR A H    1 
ATOM   3834 H HA   . TYR A 1 254 ? 10.42773  -12.37924 -6.73827  1.000 16.86277  ? 246 TYR A HA   1 
ATOM   3835 H HB2  . TYR A 1 254 ? 7.90819   -13.62581 -7.01055  1.000 18.61453  ? 246 TYR A HB2  1 
ATOM   3836 H HB3  . TYR A 1 254 ? 8.17404   -12.36033 -6.08680  1.000 18.61453  ? 246 TYR A HB3  1 
ATOM   3837 H HD1  . TYR A 1 254 ? 9.15588   -10.30533 -7.42564  1.000 16.42980  ? 246 TYR A HD1  1 
ATOM   3838 H HD2  . TYR A 1 254 ? 6.99972   -13.21408 -9.11029  1.000 27.22121  ? 246 TYR A HD2  1 
ATOM   3839 H HE1  . TYR A 1 254 ? 8.68012   -8.92063  -9.19558  1.000 18.20486  ? 246 TYR A HE1  1 
ATOM   3840 H HE2  . TYR A 1 254 ? 6.51737   -11.82176 -10.88947 1.000 22.15522  ? 246 TYR A HE2  1 
ATOM   3841 H HH   . TYR A 1 254 ? 7.31025   -8.60307  -11.01760 1.000 21.64535  ? 246 TYR A HH   1 
ATOM   3842 N N    . LYS A 1 255 ? 11.23150  -14.79020 -5.49514  1.000 14.01979  ? 247 LYS A N    1 
ATOM   3843 C CA   . LYS A 1 255 ? 11.42703  -15.61733 -4.31130  1.000 15.10544  ? 247 LYS A CA   1 
ATOM   3844 C C    . LYS A 1 255 ? 11.70142  -14.75709 -3.08176  1.000 17.73791  ? 247 LYS A C    1 
ATOM   3845 O O    . LYS A 1 255 ? 11.19523  -15.04730 -1.98743  1.000 20.34970  ? 247 LYS A O    1 
ATOM   3846 C CB   . LYS A 1 255 ? 12.53981  -16.63917 -4.56524  1.000 20.85531  ? 247 LYS A CB   1 
ATOM   3847 C CG   . LYS A 1 255 ? 12.06992  -17.84348 -5.42747  1.000 33.04723  ? 247 LYS A CG   1 
ATOM   3848 C CD   . LYS A 1 255 ? 10.59736  -18.26766 -5.14523  1.000 63.62986  ? 247 LYS A CD   1 
ATOM   3849 C CE   . LYS A 1 255 ? 10.35187  -19.74784 -5.34871  1.000 72.25733  ? 247 LYS A CE   1 
ATOM   3850 N NZ   . LYS A 1 255 ? 8.96883   -20.03855 -5.85073  1.000 69.04343  ? 247 LYS A NZ   1 
ATOM   3851 H H    . LYS A 1 255 ? 11.83518  -14.85350 -6.10437  1.000 16.84077  ? 247 LYS A H    1 
ATOM   3852 H HA   . LYS A 1 255 ? 10.61896  -16.12205 -4.12914  1.000 18.14355  ? 247 LYS A HA   1 
ATOM   3853 N N    . LEU A 1 256 ? 12.47201  -13.67624 -3.23816  1.000 14.55269  ? 248 LEU A N    1 
ATOM   3854 C CA   . LEU A 1 256 ? 12.70230  -12.78582 -2.10006  1.000 17.53005  ? 248 LEU A CA   1 
ATOM   3855 C C    . LEU A 1 256 ? 11.43103  -12.03151 -1.73075  1.000 16.38115  ? 248 LEU A C    1 
ATOM   3856 O O    . LEU A 1 256 ? 11.06244  -11.94564 -0.55170  1.000 18.83001  ? 248 LEU A O    1 
ATOM   3857 C CB   . LEU A 1 256 ? 13.82800  -11.79542 -2.39092  1.000 24.97924  ? 248 LEU A CB   1 
ATOM   3858 C CG   . LEU A 1 256 ? 14.22851  -10.95576 -1.17111  1.000 33.08469  ? 248 LEU A CG   1 
ATOM   3859 C CD1  . LEU A 1 256 ? 14.72920  -11.86253 -0.05092  1.000 25.96612  ? 248 LEU A CD1  1 
ATOM   3860 C CD2  . LEU A 1 256 ? 15.28121  -9.90617  -1.53503  1.000 28.14369  ? 248 LEU A CD2  1 
ATOM   3861 H H    . LEU A 1 256 ? 12.86033  -13.44407 -3.96953  1.000 17.48025  ? 248 LEU A H    1 
ATOM   3862 H HA   . LEU A 1 256 ? 12.97705  -13.33272 -1.34752  1.000 21.05308  ? 248 LEU A HA   1 
ATOM   3863 H HB2  . LEU A 1 256 ? 14.61033  -12.28827 -2.68409  1.000 29.99211  ? 248 LEU A HB2  1 
ATOM   3864 H HB3  . LEU A 1 256 ? 13.53762  -11.18802 -3.08924  1.000 29.99211  ? 248 LEU A HB3  1 
ATOM   3865 H HG   . LEU A 1 256 ? 13.44752  -10.47672 -0.85258  1.000 39.71864  ? 248 LEU A HG   1 
ATOM   3866 H HD11 . LEU A 1 256 ? 15.13993  -11.31651 0.63760   1.000 31.17637  ? 248 LEU A HD11 1 
ATOM   3867 H HD12 . LEU A 1 256 ? 13.97772  -12.35159 0.31920   1.000 31.17637  ? 248 LEU A HD12 1 
ATOM   3868 H HD13 . LEU A 1 256 ? 15.38087  -12.48255 -0.41397  1.000 31.17637  ? 248 LEU A HD13 1 
ATOM   3869 H HD21 . LEU A 1 256 ? 15.51009  -9.39963  -0.74010  1.000 33.78945  ? 248 LEU A HD21 1 
ATOM   3870 H HD22 . LEU A 1 256 ? 16.06905  -10.35524 -1.87934  1.000 33.78945  ? 248 LEU A HD22 1 
ATOM   3871 H HD23 . LEU A 1 256 ? 14.91615  -9.31391  -2.21094  1.000 33.78945  ? 248 LEU A HD23 1 
ATOM   3872 N N    . ALA A 1 257 ? 10.75106  -11.46920 -2.72629  1.000 14.02378  ? 249 ALA A N    1 
ATOM   3873 C CA   . ALA A 1 257 ? 9.51325   -10.75457 -2.45755  1.000 15.58212  ? 249 ALA A CA   1 
ATOM   3874 C C    . ALA A 1 257 ? 8.49154   -11.66683 -1.79887  1.000 16.53294  ? 249 ALA A C    1 
ATOM   3875 O O    . ALA A 1 257 ? 7.74809   -11.23515 -0.91141  1.000 18.78064  ? 249 ALA A O    1 
ATOM   3876 C CB   . ALA A 1 257 ? 8.95267   -10.17220 -3.75400  1.000 16.49005  ? 249 ALA A CB   1 
ATOM   3877 H H    . ALA A 1 257 ? 10.98292  -11.48759 -3.55424  1.000 16.84556  ? 249 ALA A H    1 
ATOM   3878 H HA   . ALA A 1 257 ? 9.69861   -10.01860 -1.85349  1.000 18.71557  ? 249 ALA A HA   1 
ATOM   3879 H HB1  . ALA A 1 257 ? 8.33386   -9.45730  -3.53746  1.000 19.80508  ? 249 ALA A HB1  1 
ATOM   3880 H HB2  . ALA A 1 257 ? 9.68512   -9.82553  -4.28714  1.000 19.80508  ? 249 ALA A HB2  1 
ATOM   3881 H HB3  . ALA A 1 257 ? 8.49141   -10.87265 -4.24135  1.000 19.80508  ? 249 ALA A HB3  1 
ATOM   3882 N N    . ASN A 1 258 ? 8.42747   -12.93385 -2.22379  1.000 12.48115  ? 250 ASN A N    1 
ATOM   3883 C CA   . ASN A 1 258 ? 7.41823   -13.82184 -1.65689  1.000 12.82747  ? 250 ASN A CA   1 
ATOM   3884 C C    . ASN A 1 258 ? 7.68396   -14.07866 -0.18019  1.000 18.18876  ? 250 ASN A C    1 
ATOM   3885 O O    . ASN A 1 258 ? 6.74690   -14.13201 0.62390   1.000 16.02166  ? 250 ASN A O    1 
ATOM   3886 C CB   . ASN A 1 258 ? 7.37411   -15.14025 -2.42146  1.000 12.00772  ? 250 ASN A CB   1 
ATOM   3887 C CG   . ASN A 1 258 ? 6.74921   -14.99616 -3.80676  1.000 17.41381  ? 250 ASN A CG   1 
ATOM   3888 O OD1  . ASN A 1 258 ? 6.08235   -14.00846 -4.10354  1.000 17.36754  ? 250 ASN A OD1  1 
ATOM   3889 N ND2  . ASN A 1 258 ? 6.98998   -15.97401 -4.66456  1.000 22.94489  ? 250 ASN A ND2  1 
ATOM   3890 H H    . ASN A 1 258 ? 8.93924   -13.28778 -2.81745  1.000 14.99440  ? 250 ASN A H    1 
ATOM   3891 H HA   . ASN A 1 258 ? 6.55066   -13.39730 -1.74617  1.000 15.40999  ? 250 ASN A HA   1 
ATOM   3892 H HB2  . ASN A 1 258 ? 8.27883   -15.47178 -2.53309  1.000 14.42629  ? 250 ASN A HB2  1 
ATOM   3893 H HB3  . ASN A 1 258 ? 6.84599   -15.78005 -1.91882  1.000 14.42629  ? 250 ASN A HB3  1 
ATOM   3894 H HD21 . ASN A 1 258 ? 6.66075   -15.94046 -5.45834  1.000 27.55089  ? 250 ASN A HD21 1 
ATOM   3895 H HD22 . ASN A 1 258 ? 7.47573   -16.64326 -4.42844  1.000 27.55089  ? 250 ASN A HD22 1 
ATOM   3896 N N    . ILE A 1 259 ? 8.95451   -14.24226 0.19373   1.000 12.80385  ? 251 ILE A N    1 
ATOM   3897 C CA   . ILE A 1 259 ? 9.29210   -14.48599 1.59313   1.000 10.35265  ? 251 ILE A CA   1 
ATOM   3898 C C    . ILE A 1 259 ? 9.02773   -13.25052 2.43974   1.000 12.60221  ? 251 ILE A C    1 
ATOM   3899 O O    . ILE A 1 259 ? 8.56893   -13.35442 3.58492   1.000 12.43229  ? 251 ILE A O    1 
ATOM   3900 C CB   . ILE A 1 259 ? 10.75755  -14.92034 1.72636   1.000 15.22846  ? 251 ILE A CB   1 
ATOM   3901 C CG1  . ILE A 1 259 ? 10.96617  -16.29189 1.10169   1.000 23.10213  ? 251 ILE A CG1  1 
ATOM   3902 C CG2  . ILE A 1 259 ? 11.17486  -14.93680 3.20953   1.000 20.02989  ? 251 ILE A CG2  1 
ATOM   3903 C CD1  . ILE A 1 259 ? 12.42262  -16.56601 0.76390   1.000 23.24603  ? 251 ILE A CD1  1 
ATOM   3904 H H    . ILE A 1 259 ? 9.63045   -14.21683 -0.33737  1.000 15.38164  ? 251 ILE A H    1 
ATOM   3905 H HA   . ILE A 1 259 ? 8.72265   -15.20468 1.90953   1.000 12.44020  ? 251 ILE A HA   1 
ATOM   3906 H HB   . ILE A 1 259 ? 11.31104  -14.28026 1.25219   1.000 18.29117  ? 251 ILE A HB   1 
ATOM   3907 H HG12 . ILE A 1 259 ? 10.66909  -16.97216 1.72610   1.000 27.73957  ? 251 ILE A HG12 1 
ATOM   3908 H HG13 . ILE A 1 259 ? 10.45163  -16.34719 0.28127   1.000 27.73957  ? 251 ILE A HG13 1 
ATOM   3909 H HG21 . ILE A 1 259 ? 11.92124  -15.54625 3.32084   1.000 24.05289  ? 251 ILE A HG21 1 
ATOM   3910 H HG22 . ILE A 1 259 ? 11.43698  -14.04106 3.47380   1.000 24.05289  ? 251 ILE A HG22 1 
ATOM   3911 H HG23 . ILE A 1 259 ? 10.42296  -15.23322 3.74588   1.000 24.05289  ? 251 ILE A HG23 1 
ATOM   3912 H HD11 . ILE A 1 259 ? 12.46999  -17.32774 0.16522   1.000 27.91226  ? 251 ILE A HD11 1 
ATOM   3913 H HD12 . ILE A 1 259 ? 12.79972  -15.78290 0.33328   1.000 27.91226  ? 251 ILE A HD12 1 
ATOM   3914 H HD13 . ILE A 1 259 ? 12.90592  -16.75823 1.58266   1.000 27.91226  ? 251 ILE A HD13 1 
ATOM   3915 N N    . MET A 1 260 ? 9.33577   -12.07340 1.90443   1.000 12.84252  ? 252 MET A N    1 
ATOM   3916 C CA   . MET A 1 260 ? 9.31034   -10.83210 2.66261   1.000 10.20416  ? 252 MET A CA   1 
ATOM   3917 C C    . MET A 1 260 ? 8.01510   -10.04310 2.50391   1.000 12.79010  ? 252 MET A C    1 
ATOM   3918 O O    . MET A 1 260 ? 7.82880   -9.05038  3.21083   1.000 11.24383  ? 252 MET A O    1 
ATOM   3919 C CB   . MET A 1 260 ? 10.50142  -9.96492  2.25471   1.000 9.52177   ? 252 MET A CB   1 
ATOM   3920 C CG   . MET A 1 260 ? 11.86689  -10.54765 2.62702   1.000 14.30484  ? 252 MET A CG   1 
ATOM   3921 S SD   . MET A 1 260 ? 12.10203  -10.90529 4.37733   1.000 14.48218  ? 252 MET A SD   1 
ATOM   3922 C CE   . MET A 1 260 ? 11.92910  -9.25948  5.07751   1.000 13.66128  ? 252 MET A CE   1 
ATOM   3923 H H    . MET A 1 260 ? 9.56821   -11.96727 1.08327   1.000 15.42804  ? 252 MET A H    1 
ATOM   3924 H HA   . MET A 1 260 ? 9.40356   -11.04236 3.60495   1.000 12.26202  ? 252 MET A HA   1 
ATOM   3925 H HB2  . MET A 1 260 ? 10.48454  -9.84991  1.29170   1.000 11.44314  ? 252 MET A HB2  1 
ATOM   3926 H HB3  . MET A 1 260 ? 10.42099  -9.10342  2.69318   1.000 11.44314  ? 252 MET A HB3  1 
ATOM   3927 H HG2  . MET A 1 260 ? 11.98651  -11.38001 2.14353   1.000 17.18283  ? 252 MET A HG2  1 
ATOM   3928 H HG3  . MET A 1 260 ? 12.55198  -9.91186  2.36756   1.000 17.18283  ? 252 MET A HG3  1 
ATOM   3929 H HE1  . MET A 1 260 ? 11.95109  -9.32402  6.04511   1.000 16.41056  ? 252 MET A HE1  1 
ATOM   3930 H HE2  . MET A 1 260 ? 12.66180  -8.70527  4.76623   1.000 16.41056  ? 252 MET A HE2  1 
ATOM   3931 H HE3  . MET A 1 260 ? 11.08322  -8.88140  4.79035   1.000 16.41056  ? 252 MET A HE3  1 
ATOM   3932 N N    . GLU A 1 261 ? 7.09195   -10.49892 1.65446   1.000 13.00633  ? 253 GLU A N    1 
ATOM   3933 C CA   . GLU A 1 261 ? 5.89908   -9.71651  1.34507   1.000 12.63433  ? 253 GLU A CA   1 
ATOM   3934 C C    . GLU A 1 261 ? 5.13248   -9.34372  2.60892   1.000 9.48630   ? 253 GLU A C    1 
ATOM   3935 O O    . GLU A 1 261 ? 4.73706   -8.18881  2.79479   1.000 12.91045  ? 253 GLU A O    1 
ATOM   3936 C CB   . GLU A 1 261 ? 4.99445   -10.50506 0.39422   1.000 14.46593  ? 253 GLU A CB   1 
ATOM   3937 C CG   . GLU A 1 261 ? 3.60575   -9.87969  0.21483   1.000 15.78719  ? 253 GLU A CG   1 
ATOM   3938 C CD   . GLU A 1 261 ? 2.72329   -10.64309 -0.74520  1.000 21.39841  ? 253 GLU A CD   1 
ATOM   3939 O OE1  . GLU A 1 261 ? 3.15545   -11.70261 -1.23741  1.000 21.32385  ? 253 GLU A OE1  1 
ATOM   3940 O OE2  . GLU A 1 261 ? 1.58860   -10.17596 -1.00356  1.000 23.66431  ? 253 GLU A OE2  1 
ATOM   3941 H H    . GLU A 1 261 ? 7.13369   -11.25486 1.24652   1.000 15.62462  ? 253 GLU A H    1 
ATOM   3942 H HA   . GLU A 1 261 ? 6.17372   -8.89671  0.90531   1.000 15.17822  ? 253 GLU A HA   1 
ATOM   3943 H HB2  . GLU A 1 261 ? 5.41714   -10.54622 -0.47787  1.000 17.37614  ? 253 GLU A HB2  1 
ATOM   3944 H HB3  . GLU A 1 261 ? 4.87417   -11.40052 0.74719   1.000 17.37614  ? 253 GLU A HB3  1 
ATOM   3945 H HG2  . GLU A 1 261 ? 3.15861   -9.85670  1.07532   1.000 18.96165  ? 253 GLU A HG2  1 
ATOM   3946 H HG3  . GLU A 1 261 ? 3.70959   -8.97874  -0.12927  1.000 18.96165  ? 253 GLU A HG3  1 
ATOM   3947 N N    . HIS A 1 262 ? 4.88102   -10.32658 3.47056   1.000 12.54333  ? 254 HIS A N    1 
ATOM   3948 C CA   . HIS A 1 262 ? 4.08005   -10.07668 4.66644   1.000 13.80924  ? 254 HIS A CA   1 
ATOM   3949 C C    . HIS A 1 262 ? 4.67249   -8.93217  5.47205   1.000 10.90914  ? 254 HIS A C    1 
ATOM   3950 O O    . HIS A 1 262 ? 3.97174   -7.98080  5.84513   1.000 10.97388  ? 254 HIS A O    1 
ATOM   3951 C CB   . HIS A 1 262 ? 4.00474   -11.35692 5.49815   1.000 13.50769  ? 254 HIS A CB   1 
ATOM   3952 C CG   . HIS A 1 262 ? 2.99354   -11.31198 6.59828   1.000 15.00258  ? 254 HIS A CG   1 
ATOM   3953 N ND1  . HIS A 1 262 ? 1.65449   -11.10733 6.36441   1.000 18.55000  ? 254 HIS A ND1  1 
ATOM   3954 C CD2  . HIS A 1 262 ? 3.12215   -11.49521 7.93423   1.000 16.74956  ? 254 HIS A CD2  1 
ATOM   3955 C CE1  . HIS A 1 262 ? 1.00106   -11.14104 7.51196   1.000 19.50687  ? 254 HIS A CE1  1 
ATOM   3956 N NE2  . HIS A 1 262 ? 1.86819   -11.36799 8.48075   1.000 18.18212  ? 254 HIS A NE2  1 
ATOM   3957 H H    . HIS A 1 262 ? 5.15834   -11.13643 3.38790   1.000 15.06902  ? 254 HIS A H    1 
ATOM   3958 H HA   . HIS A 1 262 ? 3.17649   -9.82909  4.41506   1.000 16.58811  ? 254 HIS A HA   1 
ATOM   3959 H HB2  . HIS A 1 262 ? 3.77059   -12.09412 4.91282   1.000 16.22625  ? 254 HIS A HB2  1 
ATOM   3960 H HB3  . HIS A 1 262 ? 4.87222   -11.51642 5.90180   1.000 16.22625  ? 254 HIS A HB3  1 
ATOM   3961 H HD2  . HIS A 1 262 ? 3.91038   -11.67344 8.39449   1.000 20.11649  ? 254 HIS A HD2  1 
ATOM   3962 H HE1  . HIS A 1 262 ? 0.08464   -11.02451 7.61915   1.000 23.42526  ? 254 HIS A HE1  1 
ATOM   3963 N N    . ASP A 1 263 ? 5.98564   -8.97777  5.68558   1.000 10.32265  ? 255 ASP A N    1 
ATOM   3964 C CA   . ASP A 1 263 ? 6.65962   -7.99155  6.51833   1.000 11.67212  ? 255 ASP A CA   1 
ATOM   3965 C C    . ASP A 1 263 ? 6.85374   -6.66949  5.79099   1.000 11.02309  ? 255 ASP A C    1 
ATOM   3966 O O    . ASP A 1 263 ? 6.76411   -5.60582  6.41471   1.000 10.92602  ? 255 ASP A O    1 
ATOM   3967 C CB   . ASP A 1 263 ? 8.00607   -8.54705  6.98590   1.000 12.53530  ? 255 ASP A CB   1 
ATOM   3968 C CG   . ASP A 1 263 ? 7.86225   -9.55151  8.11760   1.000 15.28405  ? 255 ASP A CG   1 
ATOM   3969 O OD1  . ASP A 1 263 ? 7.24019   -9.20395  9.13251   1.000 13.44303  ? 255 ASP A OD1  1 
ATOM   3970 O OD2  . ASP A 1 263 ? 8.35178   -10.69545 7.99341   1.000 14.73599  ? 255 ASP A OD2  1 
ATOM   3971 H H    . ASP A 1 263 ? 6.51111   -9.57403  5.35701   1.000 12.40420  ? 255 ASP A H    1 
ATOM   3972 H HA   . ASP A 1 263 ? 6.11943   -7.81580  7.30460   1.000 14.02357  ? 255 ASP A HA   1 
ATOM   3973 H HB2  . ASP A 1 263 ? 8.44044   -8.99267  6.24183   1.000 15.05938  ? 255 ASP A HB2  1 
ATOM   3974 H HB3  . ASP A 1 263 ? 8.55814   -7.81487  7.30217   1.000 15.05938  ? 255 ASP A HB3  1 
ATOM   3975 N N    . LEU A 1 264 ? 7.08667   -6.70247  4.47791   1.000 10.68762  ? 256 LEU A N    1 
ATOM   3976 C CA   . LEU A 1 264 ? 7.22868   -5.45308  3.74850   1.000 13.20726  ? 256 LEU A CA   1 
ATOM   3977 C C    . LEU A 1 264 ? 5.90477   -4.70231  3.69187   1.000 11.81265  ? 256 LEU A C    1 
ATOM   3978 O O    . LEU A 1 264 ? 5.88830   -3.47067  3.73236   1.000 10.93446  ? 256 LEU A O    1 
ATOM   3979 C CB   . LEU A 1 264 ? 7.76450   -5.72711  2.34920   1.000 9.40762   ? 256 LEU A CB   1 
ATOM   3980 C CG   . LEU A 1 264 ? 9.24029   -6.09292  2.28975   1.000 10.79116  ? 256 LEU A CG   1 
ATOM   3981 C CD1  . LEU A 1 264 ? 9.59423   -6.67585  0.91319   1.000 16.26920  ? 256 LEU A CD1  1 
ATOM   3982 C CD2  . LEU A 1 264 ? 10.12549  -4.89592  2.63892   1.000 14.21525  ? 256 LEU A CD2  1 
ATOM   3983 H H    . LEU A 1 264 ? 7.16385   -7.41563  4.00352   1.000 12.84216  ? 256 LEU A H    1 
ATOM   3984 H HA   . LEU A 1 264 ? 7.87169   -4.88742  4.20399   1.000 15.86573  ? 256 LEU A HA   1 
ATOM   3985 H HB2  . LEU A 1 264 ? 7.26478   -6.46621  1.96852   1.000 11.30616  ? 256 LEU A HB2  1 
ATOM   3986 H HB3  . LEU A 1 264 ? 7.63926   -4.92985  1.81105   1.000 11.30616  ? 256 LEU A HB3  1 
ATOM   3987 H HG   . LEU A 1 264 ? 9.42058   -6.77628  2.95414   1.000 12.96641  ? 256 LEU A HG   1 
ATOM   3988 H HD11 . LEU A 1 264 ? 10.53289  -6.92031  0.90562   1.000 19.54006  ? 256 LEU A HD11 1 
ATOM   3989 H HD12 . LEU A 1 264 ? 9.04682   -7.46027  0.75219   1.000 19.54006  ? 256 LEU A HD12 1 
ATOM   3990 H HD13 . LEU A 1 264 ? 9.42125   -6.00646  0.23282   1.000 19.54006  ? 256 LEU A HD13 1 
ATOM   3991 H HD21 . LEU A 1 264 ? 11.05447  -5.14000  2.50356   1.000 17.07532  ? 256 LEU A HD21 1 
ATOM   3992 H HD22 . LEU A 1 264 ? 9.89173   -4.15151  2.06263   1.000 17.07532  ? 256 LEU A HD22 1 
ATOM   3993 H HD23 . LEU A 1 264 ? 9.97871   -4.65463  3.56689   1.000 17.07532  ? 256 LEU A HD23 1 
ATOM   3994 N N    . LYS A 1 265 ? 4.78573   -5.42236  3.58218   1.000 11.93148  ? 257 LYS A N    1 
ATOM   3995 C CA   . LYS A 1 265 ? 3.49215   -4.75808  3.67965   1.000 10.48881  ? 257 LYS A CA   1 
ATOM   3996 C C    . LYS A 1 265 ? 3.36757   -4.02848  5.01078   1.000 11.42755  ? 257 LYS A C    1 
ATOM   3997 O O    . LYS A 1 265 ? 2.88037   -2.89527  5.06715   1.000 14.01315  ? 257 LYS A O    1 
ATOM   3998 C CB   . LYS A 1 265 ? 2.36032   -5.77392  3.51925   1.000 10.92443  ? 257 LYS A CB   1 
ATOM   3999 C CG   . LYS A 1 265 ? 2.17970   -6.26993  2.10205   1.000 13.77953  ? 257 LYS A CG   1 
ATOM   4000 C CD   . LYS A 1 265 ? 1.43020   -7.61305  2.05310   1.000 23.06476  ? 257 LYS A CD   1 
ATOM   4001 C CE   . LYS A 1 265 ? 0.02461   -7.50335  2.58510   1.000 29.21701  ? 257 LYS A CE   1 
ATOM   4002 N NZ   . LYS A 1 265 ? -0.64512  -8.84772  2.57860   1.000 29.79971  ? 257 LYS A NZ   1 
ATOM   4003 H H    . LYS A 1 265 ? 4.75186   -6.27219  3.45478   1.000 14.33480  ? 257 LYS A H    1 
ATOM   4004 H HA   . LYS A 1 265 ? 3.41204   -4.11153  2.96100   1.000 12.60360  ? 257 LYS A HA   1 
ATOM   4005 H HB2  . LYS A 1 265 ? 2.55009   -6.54260  4.07963   1.000 13.12634  ? 257 LYS A HB2  1 
ATOM   4006 H HB3  . LYS A 1 265 ? 1.52818   -5.35918  3.79570   1.000 13.12634  ? 257 LYS A HB3  1 
ATOM   4007 H HG2  . LYS A 1 265 ? 1.66694   -5.61847  1.59848   1.000 16.55246  ? 257 LYS A HG2  1 
ATOM   4008 H HG3  . LYS A 1 265 ? 3.05069   -6.39410  1.69358   1.000 16.55246  ? 257 LYS A HG3  1 
ATOM   4009 H HD2  . LYS A 1 265 ? 1.38149   -7.91695  1.13322   1.000 27.69474  ? 257 LYS A HD2  1 
ATOM   4010 H HD3  . LYS A 1 265 ? 1.90680   -8.26327  2.59251   1.000 27.69474  ? 257 LYS A HD3  1 
ATOM   4011 H HE2  . LYS A 1 265 ? 0.04689   -7.17310  3.49688   1.000 35.07743  ? 257 LYS A HE2  1 
ATOM   4012 H HE3  . LYS A 1 265 ? -0.48850  -6.89927  2.02590   1.000 35.07743  ? 257 LYS A HE3  1 
ATOM   4013 H HZ1  . LYS A 1 265 ? -1.17975  -8.91804  1.87056   1.000 35.77667  ? 257 LYS A HZ1  1 
ATOM   4014 H HZ2  . LYS A 1 265 ? -0.03282  -9.49266  2.54338   1.000 35.77667  ? 257 LYS A HZ2  1 
ATOM   4015 H HZ3  . LYS A 1 265 ? -1.12998  -8.94983  3.31791   1.000 35.77667  ? 257 LYS A HZ3  1 
ATOM   4016 N N    . GLY A 1 266 ? 3.80769   -4.66568  6.09527   1.000 9.24957   ? 258 GLY A N    1 
ATOM   4017 C CA   . GLY A 1 266 ? 3.66939   -4.05343  7.40550   1.000 10.14114  ? 258 GLY A CA   1 
ATOM   4018 C C    . GLY A 1 266 ? 4.59601   -2.86935  7.57708   1.000 12.81860  ? 258 GLY A C    1 
ATOM   4019 O O    . GLY A 1 266 ? 4.23616   -1.86502  8.20388   1.000 13.65459  ? 258 GLY A O    1 
ATOM   4020 H H    . GLY A 1 266 ? 4.18295   -5.43949  6.09633   1.000 11.11651  ? 258 GLY A H    1 
ATOM   4021 H HA2  . GLY A 1 266 ? 2.75609   -3.74917  7.52474   1.000 12.18639  ? 258 GLY A HA2  1 
ATOM   4022 H HA3  . GLY A 1 266 ? 3.87628   -4.70784  8.09095   1.000 12.18639  ? 258 GLY A HA3  1 
ATOM   4023 N N    . LEU A 1 267 ? 5.80012   -2.95967  7.01269   1.000 11.48515  ? 259 LEU A N    1 
ATOM   4024 C CA   . LEU A 1 267 ? 6.70846   -1.82648  7.09133   1.000 12.21814  ? 259 LEU A CA   1 
ATOM   4025 C C    . LEU A 1 267 ? 6.15990   -0.64092  6.30486   1.000 16.09520  ? 259 LEU A C    1 
ATOM   4026 O O    . LEU A 1 267 ? 6.24590   0.50663   6.75550   1.000 12.71216  ? 259 LEU A O    1 
ATOM   4027 C CB   . LEU A 1 267 ? 8.08616   -2.23372  6.58607   1.000 10.24192  ? 259 LEU A CB   1 
ATOM   4028 C CG   . LEU A 1 267 ? 9.16470   -1.17279  6.75070   1.000 10.81866  ? 259 LEU A CG   1 
ATOM   4029 C CD1  . LEU A 1 267 ? 9.35960   -0.81609  8.21848   1.000 15.58507  ? 259 LEU A CD1  1 
ATOM   4030 C CD2  . LEU A 1 267 ? 10.46856  -1.63310  6.14452   1.000 14.83719  ? 259 LEU A CD2  1 
ATOM   4031 H H    . LEU A 1 267 ? 6.10325   -3.64580  6.59206   1.000 13.79921  ? 259 LEU A H    1 
ATOM   4032 H HA   . LEU A 1 267 ? 6.80562   -1.55112  8.01634   1.000 14.67878  ? 259 LEU A HA   1 
ATOM   4033 H HB2  . LEU A 1 267 ? 8.37273   -3.02058  7.07559   1.000 12.30732  ? 259 LEU A HB2  1 
ATOM   4034 H HB3  . LEU A 1 267 ? 8.01857   -2.43781  5.64020   1.000 12.30732  ? 259 LEU A HB3  1 
ATOM   4035 H HG   . LEU A 1 267 ? 8.87994   -0.37225  6.28278   1.000 12.99942  ? 259 LEU A HG   1 
ATOM   4036 H HD11 . LEU A 1 267 ? 10.13165  -0.23490  8.30241   1.000 18.71910  ? 259 LEU A HD11 1 
ATOM   4037 H HD12 . LEU A 1 267 ? 8.56614   -0.36067  8.54085   1.000 18.71910  ? 259 LEU A HD12 1 
ATOM   4038 H HD13 . LEU A 1 267 ? 9.50223   -1.63080  8.72522   1.000 18.71910  ? 259 LEU A HD13 1 
ATOM   4039 H HD21 . LEU A 1 267 ? 11.13504  -0.93854  6.26412   1.000 17.82166  ? 259 LEU A HD21 1 
ATOM   4040 H HD22 . LEU A 1 267 ? 10.75435  -2.44599  6.58997   1.000 17.82166  ? 259 LEU A HD22 1 
ATOM   4041 H HD23 . LEU A 1 267 ? 10.33449  -1.80361  5.19909   1.000 17.82166  ? 259 LEU A HD23 1 
ATOM   4042 N N    . ALA A 1 268 ? 5.58976   -0.90114  5.12849   1.000 10.60293  ? 260 ALA A N    1 
ATOM   4043 C CA   . ALA A 1 268 ? 4.99237   0.17089   4.33815   1.000 11.37381  ? 260 ALA A CA   1 
ATOM   4044 C C    . ALA A 1 268 ? 3.86148   0.84192   5.10471   1.000 9.54924   ? 260 ALA A C    1 
ATOM   4045 O O    . ALA A 1 268 ? 3.76838   2.07449   5.15011   1.000 13.14230  ? 260 ALA A O    1 
ATOM   4046 C CB   . ALA A 1 268 ? 4.48083   -0.38345  3.00853   1.000 14.68227  ? 260 ALA A CB   1 
ATOM   4047 H H    . ALA A 1 268 ? 5.53645   -1.68103  4.76997   1.000 12.74054  ? 260 ALA A H    1 
ATOM   4048 H HA   . ALA A 1 268 ? 5.67101   0.83719   4.14740   1.000 13.66560  ? 260 ALA A HA   1 
ATOM   4049 H HB1  . ALA A 1 268 ? 4.09813   0.34175   2.49034   1.000 17.63575  ? 260 ALA A HB1  1 
ATOM   4050 H HB2  . ALA A 1 268 ? 5.22267   -0.77972  2.52527   1.000 17.63575  ? 260 ALA A HB2  1 
ATOM   4051 H HB3  . ALA A 1 268 ? 3.80468   -1.05593  3.18596   1.000 17.63575  ? 260 ALA A HB3  1 
ATOM   4052 N N    . VAL A 1 269 ? 2.98653   0.04530   5.71359   1.000 11.33109  ? 261 VAL A N    1 
ATOM   4053 C CA   . VAL A 1 269 ? 1.92995   0.60507   6.55853   1.000 14.32632  ? 261 VAL A CA   1 
ATOM   4054 C C    . VAL A 1 269 ? 2.53135   1.52153   7.61800   1.000 14.77548  ? 261 VAL A C    1 
ATOM   4055 O O    . VAL A 1 269 ? 2.05857   2.63909   7.84838   1.000 13.48493  ? 261 VAL A O    1 
ATOM   4056 C CB   . VAL A 1 269 ? 1.10474   -0.52265  7.20361   1.000 17.19766  ? 261 VAL A CB   1 
ATOM   4057 C CG1  . VAL A 1 269 ? 0.19480   0.02442   8.30015   1.000 17.85930  ? 261 VAL A CG1  1 
ATOM   4058 C CG2  . VAL A 1 269 ? 0.29213   -1.25755  6.14479   1.000 18.91099  ? 261 VAL A CG2  1 
ATOM   4059 H H    . VAL A 1 269 ? 2.98071   -0.81276  5.65620   1.000 13.61433  ? 261 VAL A H    1 
ATOM   4060 H HA   . VAL A 1 269 ? 1.33782   1.13352   6.00085   1.000 17.20861  ? 261 VAL A HA   1 
ATOM   4061 H HB   . VAL A 1 269 ? 1.71335   -1.15617  7.61490   1.000 20.65421  ? 261 VAL A HB   1 
ATOM   4062 H HG11 . VAL A 1 269 ? -0.47940  -0.64008  8.51179   1.000 21.44819  ? 261 VAL A HG11 1 
ATOM   4063 H HG12 . VAL A 1 269 ? 0.72862   0.21627   9.08700   1.000 21.44819  ? 261 VAL A HG12 1 
ATOM   4064 H HG13 . VAL A 1 269 ? -0.22964  0.83666   7.98229   1.000 21.44819  ? 261 VAL A HG13 1 
ATOM   4065 H HG21 . VAL A 1 269 ? -0.20151  -1.97701  6.56857   1.000 22.71021  ? 261 VAL A HG21 1 
ATOM   4066 H HG22 . VAL A 1 269 ? -0.32369  -0.63348  5.72982   1.000 22.71021  ? 261 VAL A HG22 1 
ATOM   4067 H HG23 . VAL A 1 269 ? 0.89631   -1.61912  5.47761   1.000 22.71021  ? 261 VAL A HG23 1 
ATOM   4068 N N    . SER A 1 270 ? 3.59548   1.06211   8.26627   1.000 12.27312  ? 262 SER A N    1 
ATOM   4069 C CA   . SER A 1 270 ? 4.17860   1.81830   9.36563   1.000 14.11276  ? 262 SER A CA   1 
ATOM   4070 C C    . SER A 1 270 ? 4.82487   3.11188   8.89650   1.000 18.15921  ? 262 SER A C    1 
ATOM   4071 O O    . SER A 1 270 ? 4.93260   4.05983   9.68603   1.000 17.11420  ? 262 SER A O    1 
ATOM   4072 C CB   . SER A 1 270 ? 5.21514   0.96670   10.09583  1.000 15.22485  ? 262 SER A CB   1 
ATOM   4073 O OG   . SER A 1 270 ? 5.81378   1.70260   11.14588  1.000 22.91453  ? 262 SER A OG   1 
ATOM   4074 H H    . SER A 1 270 ? 3.99593   0.32147   8.09108   1.000 14.74477  ? 262 SER A H    1 
ATOM   4075 H HA   . SER A 1 270 ? 3.46684   2.04427   9.98469   1.000 16.95234  ? 262 SER A HA   1 
ATOM   4076 H HB2  . SER A 1 270 ? 4.77781   0.18431   10.46664  1.000 18.28684  ? 262 SER A HB2  1 
ATOM   4077 H HB3  . SER A 1 270 ? 5.90230   0.69590   9.46704   1.000 18.28684  ? 262 SER A HB3  1 
ATOM   4078 H HG   . SER A 1 270 ? 6.40179   1.23701   11.52413  1.000 27.51445  ? 262 SER A HG   1 
ATOM   4079 N N    . PHE A 1 271 ? 5.26185   3.16508   7.63374   1.000 14.73071  ? 263 PHE A N    1 
ATOM   4080 C CA   . PHE A 1 271 ? 5.87944   4.34869   7.03920   1.000 17.26263  ? 263 PHE A CA   1 
ATOM   4081 C C    . PHE A 1 271 ? 4.86512   5.24345   6.33375   1.000 15.46368  ? 263 PHE A C    1 
ATOM   4082 O O    . PHE A 1 271 ? 5.25018   6.28672   5.79442   1.000 19.01240  ? 263 PHE A O    1 
ATOM   4083 C CB   . PHE A 1 271 ? 6.94601   3.97588   5.98356   1.000 17.91310  ? 263 PHE A CB   1 
ATOM   4084 C CG   . PHE A 1 271 ? 8.26093   3.51446   6.53507   1.000 22.21087  ? 263 PHE A CG   1 
ATOM   4085 C CD1  . PHE A 1 271 ? 8.63356   3.78501   7.84074   1.000 21.07716  ? 263 PHE A CD1  1 
ATOM   4086 C CD2  . PHE A 1 271 ? 9.14928   2.82020   5.71565   1.000 20.58669  ? 263 PHE A CD2  1 
ATOM   4087 C CE1  . PHE A 1 271 ? 9.86564   3.35299   8.33478   1.000 21.62740  ? 263 PHE A CE1  1 
ATOM   4088 C CE2  . PHE A 1 271 ? 10.37223  2.37141   6.20510   1.000 28.24540  ? 263 PHE A CE2  1 
ATOM   4089 C CZ   . PHE A 1 271 ? 10.72616  2.64023   7.52114   1.000 25.75798  ? 263 PHE A CZ   1 
ATOM   4090 H H    . PHE A 1 271 ? 5.20862   2.50468   7.08544   1.000 17.69387  ? 263 PHE A H    1 
ATOM   4091 H HA   . PHE A 1 271 ? 6.31472   4.82616   7.76270   1.000 20.73217  ? 263 PHE A HA   1 
ATOM   4092 H HB2  . PHE A 1 271 ? 6.59464   3.25759   5.43446   1.000 21.51274  ? 263 PHE A HB2  1 
ATOM   4093 H HB3  . PHE A 1 271 ? 7.12028   4.75730   5.43592   1.000 21.51274  ? 263 PHE A HB3  1 
ATOM   4094 H HD1  . PHE A 1 271 ? 8.05678   4.25974   8.39468   1.000 25.30961  ? 263 PHE A HD1  1 
ATOM   4095 H HD2  . PHE A 1 271 ? 8.92154   2.65454   4.82931   1.000 24.72105  ? 263 PHE A HD2  1 
ATOM   4096 H HE1  . PHE A 1 271 ? 10.10764  3.54487   9.21200   1.000 25.96991  ? 263 PHE A HE1  1 
ATOM   4097 H HE2  . PHE A 1 271 ? 10.94951  1.89401   5.65398   1.000 33.91151  ? 263 PHE A HE2  1 
ATOM   4098 H HZ   . PHE A 1 271 ? 11.54119  2.34099   7.85443   1.000 30.92659  ? 263 PHE A HZ   1 
ATOM   4099 N N    . LYS A 1 272 ? 3.59927   4.83114   6.26209   1.000 15.19541  ? 264 LYS A N    1 
ATOM   4100 C CA   . LYS A 1 272 ? 2.58375   5.53436   5.47649   1.000 15.19304  ? 264 LYS A CA   1 
ATOM   4101 C C    . LYS A 1 272 ? 2.96701   5.52765   3.99824   1.000 19.71298  ? 264 LYS A C    1 
ATOM   4102 O O    . LYS A 1 272 ? 2.73643   6.48900   3.26086   1.000 19.19342  ? 264 LYS A O    1 
ATOM   4103 C CB   . LYS A 1 272 ? 2.35483   6.96052   5.97805   1.000 17.10944  ? 264 LYS A CB   1 
ATOM   4104 C CG   . LYS A 1 272 ? 0.98517   7.48967   5.60667   1.000 18.69102  ? 264 LYS A CG   1 
ATOM   4105 C CD   . LYS A 1 272 ? 0.75886   8.90349   6.10819   1.000 26.23740  ? 264 LYS A CD   1 
ATOM   4106 C CE   . LYS A 1 272 ? -0.55967  9.46526   5.59046   1.000 38.37266  ? 264 LYS A CE   1 
ATOM   4107 N NZ   . LYS A 1 272 ? -0.74843  10.88930  5.98174   1.000 46.73449  ? 264 LYS A NZ   1 
ATOM   4108 H H    . LYS A 1 272 ? 3.29824   4.13446   6.66659   1.000 18.25151  ? 264 LYS A H    1 
ATOM   4109 H HA   . LYS A 1 272 ? 1.73974   5.06663   5.57540   1.000 18.24867  ? 264 LYS A HA   1 
ATOM   4110 H HB2  . LYS A 1 272 ? 2.43126   6.97270   6.94496   1.000 20.54835  ? 264 LYS A HB2  1 
ATOM   4111 H HB3  . LYS A 1 272 ? 3.02131   7.54563   5.58518   1.000 20.54835  ? 264 LYS A HB3  1 
ATOM   4112 H HG2  . LYS A 1 272 ? 0.89713   7.49475   4.64068   1.000 22.44624  ? 264 LYS A HG2  1 
ATOM   4113 H HG3  . LYS A 1 272 ? 0.30626   6.91844   5.99868   1.000 22.44624  ? 264 LYS A HG3  1 
ATOM   4114 H HD2  . LYS A 1 272 ? 0.73146   8.90149   7.07780   1.000 31.50190  ? 264 LYS A HD2  1 
ATOM   4115 H HD3  . LYS A 1 272 ? 1.47845   9.47511   5.79782   1.000 31.50190  ? 264 LYS A HD3  1 
ATOM   4116 H HE2  . LYS A 1 272 ? -0.57112  9.41271   4.62195   1.000 46.06422  ? 264 LYS A HE2  1 
ATOM   4117 H HE3  . LYS A 1 272 ? -1.29366  8.94946   5.95939   1.000 46.06422  ? 264 LYS A HE3  1 
ATOM   4118 H HZ1  . LYS A 1 272 ? -1.28429  11.29653  5.39940   1.000 56.09842  ? 264 LYS A HZ1  1 
ATOM   4119 H HZ2  . LYS A 1 272 ? -1.11344  10.93652  6.79207   1.000 56.09842  ? 264 LYS A HZ2  1 
ATOM   4120 H HZ3  . LYS A 1 272 ? 0.03667   11.30832  5.99374   1.000 56.09842  ? 264 LYS A HZ3  1 
ATOM   4121 N N    . GLY A 1 273 ? 3.55308   4.41974   3.56290   1.000 15.22981  ? 265 GLY A N    1 
ATOM   4122 C CA   . GLY A 1 273 ? 3.88941   4.22903   2.17135   1.000 15.47380  ? 265 GLY A CA   1 
ATOM   4123 C C    . GLY A 1 273 ? 3.16536   3.04625   1.56436   1.000 15.81079  ? 265 GLY A C    1 
ATOM   4124 O O    . GLY A 1 273 ? 2.26205   2.47469   2.17855   1.000 17.53778  ? 265 GLY A O    1 
ATOM   4125 H H    . GLY A 1 273 ? 3.76751   3.75610   4.06609   1.000 18.29279  ? 265 GLY A H    1 
ATOM   4126 H HA2  . GLY A 1 273 ? 3.65023   5.02473   1.67079   1.000 18.58559  ? 265 GLY A HA2  1 
ATOM   4127 H HA3  . GLY A 1 273 ? 4.84422   4.07923   2.08896   1.000 18.58559  ? 265 GLY A HA3  1 
ATOM   4128 N N    . LYS A 1 274 ? 3.55209   2.66718   0.35360   1.000 16.04522  ? 266 LYS A N    1 
ATOM   4129 C CA   . LYS A 1 274 ? 2.92260   1.56645   -0.36103  1.000 17.12425  ? 266 LYS A CA   1 
ATOM   4130 C C    . LYS A 1 274 ? 3.99301   0.60338   -0.84239  1.000 12.57784  ? 266 LYS A C    1 
ATOM   4131 O O    . LYS A 1 274 ? 4.97675   1.04012   -1.44772  1.000 15.53449  ? 266 LYS A O    1 
ATOM   4132 C CB   . LYS A 1 274 ? 2.11774   2.09562   -1.55438  1.000 20.97078  ? 266 LYS A CB   1 
ATOM   4133 C CG   . LYS A 1 274 ? 1.12840   1.08755   -2.13106  1.000 35.44330  ? 266 LYS A CG   1 
ATOM   4134 C CD   . LYS A 1 274 ? 0.30551   1.71526   -3.25765  1.000 39.29090  ? 266 LYS A CD   1 
ATOM   4135 C CE   . LYS A 1 274 ? -0.59369  0.68420   -3.92771  1.000 34.90696  ? 266 LYS A CE   1 
ATOM   4136 N NZ   . LYS A 1 274 ? -1.40041  -0.09453  -2.93631  1.000 41.68188  ? 266 LYS A NZ   1 
ATOM   4137 H H    . LYS A 1 274 ? 4.19125   3.04079   -0.08398  1.000 19.27128  ? 266 LYS A H    1 
ATOM   4138 H HA   . LYS A 1 274 ? 2.32802   1.08368   0.23421   1.000 20.56612  ? 266 LYS A HA   1 
ATOM   4139 H HB2  . LYS A 1 274 ? 1.61374   2.87371   -1.26898  1.000 25.18196  ? 266 LYS A HB2  1 
ATOM   4140 H HB3  . LYS A 1 274 ? 2.73488   2.34109   -2.26133  1.000 25.18196  ? 266 LYS A HB3  1 
ATOM   4141 H HG2  . LYS A 1 274 ? 1.61274   0.32786   -2.49049  1.000 42.54898  ? 266 LYS A HG2  1 
ATOM   4142 H HG3  . LYS A 1 274 ? 0.52149   0.79421   -1.43356  1.000 42.54898  ? 266 LYS A HG3  1 
ATOM   4143 H HD2  . LYS A 1 274 ? -0.25455  2.41873   -2.89382  1.000 47.16611  ? 266 LYS A HD2  1 
ATOM   4144 H HD3  . LYS A 1 274 ? 0.90367   2.08079   -3.92810  1.000 47.16611  ? 266 LYS A HD3  1 
ATOM   4145 H HE2  . LYS A 1 274 ? -1.20744  1.13823   -4.52610  1.000 41.90537  ? 266 LYS A HE2  1 
ATOM   4146 H HE3  . LYS A 1 274 ? -0.04455  0.05968   -4.42703  1.000 41.90537  ? 266 LYS A HE3  1 
ATOM   4147 H HZ1  . LYS A 1 274 ? -1.03198  -0.89396  -2.80491  1.000 50.03528  ? 266 LYS A HZ1  1 
ATOM   4148 H HZ2  . LYS A 1 274 ? -1.43134  0.34030   -2.16038  1.000 50.03528  ? 266 LYS A HZ2  1 
ATOM   4149 H HZ3  . LYS A 1 274 ? -2.23012  -0.20506  -3.23874  1.000 50.03528  ? 266 LYS A HZ3  1 
ATOM   4150 N N    . TYR A 1 275 ? 3.77639   -0.69943  -0.61836  1.000 13.91374  ? 267 TYR A N    1 
ATOM   4151 C CA   . TYR A 1 275 ? 4.69103   -1.73328  -1.09444  1.000 12.77877  ? 267 TYR A CA   1 
ATOM   4152 C C    . TYR A 1 275 ? 4.20586   -2.23983  -2.44759  1.000 18.02163  ? 267 TYR A C    1 
ATOM   4153 O O    . TYR A 1 275 ? 3.07748   -2.73815  -2.56475  1.000 16.41348  ? 267 TYR A O    1 
ATOM   4154 C CB   . TYR A 1 275 ? 4.80094   -2.89551  -0.10694  1.000 14.97414  ? 267 TYR A CB   1 
ATOM   4155 C CG   . TYR A 1 275 ? 5.59015   -4.07182  -0.62945  1.000 13.29010  ? 267 TYR A CG   1 
ATOM   4156 C CD1  . TYR A 1 275 ? 6.85850   -3.90209  -1.17783  1.000 10.56450  ? 267 TYR A CD1  1 
ATOM   4157 C CD2  . TYR A 1 275 ? 5.07285   -5.36411  -0.56380  1.000 16.42709  ? 267 TYR A CD2  1 
ATOM   4158 C CE1  . TYR A 1 275 ? 7.58874   -4.98857  -1.65732  1.000 16.09223  ? 267 TYR A CE1  1 
ATOM   4159 C CE2  . TYR A 1 275 ? 5.78111   -6.44337  -1.04230  1.000 13.44315  ? 267 TYR A CE2  1 
ATOM   4160 C CZ   . TYR A 1 275 ? 7.03826   -6.26177  -1.58571  1.000 15.12871  ? 267 TYR A CZ   1 
ATOM   4161 O OH   . TYR A 1 275 ? 7.74687   -7.34237  -2.06599  1.000 17.38738  ? 267 TYR A OH   1 
ATOM   4162 H H    . TYR A 1 275 ? 3.09850   -1.00777  -0.18826  1.000 16.71351  ? 267 TYR A H    1 
ATOM   4163 H HA   . TYR A 1 275 ? 5.57405   -1.34395  -1.19238  1.000 15.35154  ? 267 TYR A HA   1 
ATOM   4164 H HB2  . TYR A 1 275 ? 5.24042   -2.57930  0.69790   1.000 17.98600  ? 267 TYR A HB2  1 
ATOM   4165 H HB3  . TYR A 1 275 ? 3.90787   -3.20967  0.10431   1.000 17.98600  ? 267 TYR A HB3  1 
ATOM   4166 H HD1  . TYR A 1 275 ? 7.22517   -3.04873  -1.22513  1.000 12.69443  ? 267 TYR A HD1  1 
ATOM   4167 H HD2  . TYR A 1 275 ? 4.23252   -5.50019  -0.18932  1.000 19.72954  ? 267 TYR A HD2  1 
ATOM   4168 H HE1  . TYR A 1 275 ? 8.43524   -4.86222  -2.02116  1.000 19.32770  ? 267 TYR A HE1  1 
ATOM   4169 H HE2  . TYR A 1 275 ? 5.41264   -7.29619  -0.99966  1.000 16.14881  ? 267 TYR A HE2  1 
ATOM   4170 H HH   . TYR A 1 275 ? 7.29246   -8.04391  -1.98264  1.000 20.88188  ? 267 TYR A HH   1 
ATOM   4171 N N    . LEU A 1 276 ? 5.05260   -2.10494  -3.46815  1.000 14.87168  ? 268 LEU A N    1 
ATOM   4172 C CA   . LEU A 1 276 ? 4.73841   -2.57620  -4.81522  1.000 20.24495  ? 268 LEU A CA   1 
ATOM   4173 C C    . LEU A 1 276 ? 5.57038   -3.83041  -5.03367  1.000 21.49029  ? 268 LEU A C    1 
ATOM   4174 O O    . LEU A 1 276 ? 6.76658   -3.76765  -5.31218  1.000 21.21378  ? 268 LEU A O    1 
ATOM   4175 C CB   . LEU A 1 276 ? 5.01326   -1.50881  -5.86537  1.000 13.16151  ? 268 LEU A CB   1 
ATOM   4176 C CG   . LEU A 1 276 ? 4.18019   -0.23566  -5.74522  1.000 20.03433  ? 268 LEU A CG   1 
ATOM   4177 C CD1  . LEU A 1 276 ? 4.63726   0.80716   -6.75631  1.000 24.51685  ? 268 LEU A CD1  1 
ATOM   4178 C CD2  . LEU A 1 276 ? 2.70465   -0.54338  -5.90379  1.000 21.23416  ? 268 LEU A CD2  1 
ATOM   4179 H H    . LEU A 1 276 ? 5.82747   -1.73763  -3.40289  1.000 17.86304  ? 268 LEU A H    1 
ATOM   4180 H HA   . LEU A 1 276 ? 3.79604   -2.79628  -4.88162  1.000 24.31096  ? 268 LEU A HA   1 
ATOM   4181 H HB2  . LEU A 1 276 ? 5.94607   -1.25099  -5.79984  1.000 15.81084  ? 268 LEU A HB2  1 
ATOM   4182 H HB3  . LEU A 1 276 ? 4.83488   -1.88940  -6.73957  1.000 15.81084  ? 268 LEU A HB3  1 
ATOM   4183 H HG   . LEU A 1 276 ? 4.30746   0.14084   -4.86038  1.000 24.05822  ? 268 LEU A HG   1 
ATOM   4184 H HD11 . LEU A 1 276 ? 4.07652   1.59432   -6.67355  1.000 29.43724  ? 268 LEU A HD11 1 
ATOM   4185 H HD12 . LEU A 1 276 ? 5.56156   1.03893   -6.57503  1.000 29.43724  ? 268 LEU A HD12 1 
ATOM   4186 H HD13 . LEU A 1 276 ? 4.55810   0.43706   -7.64942  1.000 29.43724  ? 268 LEU A HD13 1 
ATOM   4187 H HD21 . LEU A 1 276 ? 2.20866   0.28998   -5.92414  1.000 25.49802  ? 268 LEU A HD21 1 
ATOM   4188 H HD22 . LEU A 1 276 ? 2.57054   -1.02846  -6.73301  1.000 25.49802  ? 268 LEU A HD22 1 
ATOM   4189 H HD23 . LEU A 1 276 ? 2.41237   -1.08402  -5.15333  1.000 25.49802  ? 268 LEU A HD23 1 
ATOM   4190 N N    . LYS A 1 277 ? 4.92934   -4.97674  -4.88645  1.000 13.87409  ? 269 LYS A N    1 
ATOM   4191 C CA   . LYS A 1 277 ? 5.64921   -6.24275  -4.92481  1.000 11.83972  ? 269 LYS A CA   1 
ATOM   4192 C C    . LYS A 1 277 ? 6.17968   -6.55382  -6.31675  1.000 12.70246  ? 269 LYS A C    1 
ATOM   4193 O O    . LYS A 1 277 ? 7.27679   -7.10725  -6.46085  1.000 17.54720  ? 269 LYS A O    1 
ATOM   4194 C CB   . LYS A 1 277 ? 4.71575   -7.36284  -4.46002  1.000 22.56056  ? 269 LYS A CB   1 
ATOM   4195 C CG   . LYS A 1 277 ? 5.35612   -8.70470  -4.36553  1.000 15.66121  ? 269 LYS A CG   1 
ATOM   4196 C CD   . LYS A 1 277 ? 4.30433   -9.81087  -4.20737  1.000 21.17912  ? 269 LYS A CD   1 
ATOM   4197 C CE   . LYS A 1 277 ? 4.97414   -11.18078 -4.05455  1.000 22.73721  ? 269 LYS A CE   1 
ATOM   4198 N NZ   . LYS A 1 277 ? 3.94521   -12.24516 -3.84055  1.000 28.42539  ? 269 LYS A NZ   1 
ATOM   4199 H H    . LYS A 1 277 ? 4.08163   -5.05313  -4.76335  1.000 16.66593  ? 269 LYS A H    1 
ATOM   4200 H HA   . LYS A 1 277 ? 6.40998   -6.18713  -4.32562  1.000 14.22469  ? 269 LYS A HA   1 
ATOM   4201 H HB2  . LYS A 1 277 ? 4.37787   -7.13727  -3.57920  1.000 27.08969  ? 269 LYS A HB2  1 
ATOM   4202 H HB3  . LYS A 1 277 ? 3.98089   -7.43305  -5.08927  1.000 27.08969  ? 269 LYS A HB3  1 
ATOM   4203 H HG2  . LYS A 1 277 ? 5.86329   -8.87772  -5.17408  1.000 18.81048  ? 269 LYS A HG2  1 
ATOM   4204 H HG3  . LYS A 1 277 ? 5.94358   -8.72814  -3.59402  1.000 18.81048  ? 269 LYS A HG3  1 
ATOM   4205 H HD2  . LYS A 1 277 ? 3.77028   -9.63937  -3.41599  1.000 25.43197  ? 269 LYS A HD2  1 
ATOM   4206 H HD3  . LYS A 1 277 ? 3.73585   -9.83212  -4.99304  1.000 25.43197  ? 269 LYS A HD3  1 
ATOM   4207 H HE2  . LYS A 1 277 ? 5.47312   -11.39024 -4.85957  1.000 27.30168  ? 269 LYS A HE2  1 
ATOM   4208 H HE3  . LYS A 1 277 ? 5.56970   -11.16783 -3.28902  1.000 27.30168  ? 269 LYS A HE3  1 
ATOM   4209 H HZ1  . LYS A 1 277 ? 4.31639   -13.04933 -3.92798  1.000 34.12749  ? 269 LYS A HZ1  1 
ATOM   4210 H HZ2  . LYS A 1 277 ? 3.59906   -12.17407 -3.02371  1.000 34.12749  ? 269 LYS A HZ2  1 
ATOM   4211 H HZ3  . LYS A 1 277 ? 3.29202   -12.16188 -4.43930  1.000 34.12749  ? 269 LYS A HZ3  1 
ATOM   4212 N N    . ASP A 1 278 ? 5.39166   -6.27559  -7.34617  1.000 12.15649  ? 270 ASP A N    1 
ATOM   4213 C CA   . ASP A 1 278 ? 5.70753   -6.67874  -8.70737  1.000 11.64716  ? 270 ASP A CA   1 
ATOM   4214 C C    . ASP A 1 278 ? 5.84238   -5.46478  -9.62134  1.000 12.94338  ? 270 ASP A C    1 
ATOM   4215 O O    . ASP A 1 278 ? 5.41631   -5.47656  -10.77682 1.000 16.14250  ? 270 ASP A O    1 
ATOM   4216 C CB   . ASP A 1 278 ? 4.65926   -7.66270  -9.23108  1.000 14.75455  ? 270 ASP A CB   1 
ATOM   4217 C CG   . ASP A 1 278 ? 3.27234   -7.05159  -9.35380  1.000 16.83439  ? 270 ASP A CG   1 
ATOM   4218 O OD1  . ASP A 1 278 ? 2.98865   -6.03719  -8.68006  1.000 15.62777  ? 270 ASP A OD1  1 
ATOM   4219 O OD2  . ASP A 1 278 ? 2.45233   -7.60124  -10.14027 1.000 21.20315  ? 270 ASP A OD2  1 
ATOM   4220 H H    . ASP A 1 278 ? 4.65101   -5.84383  -7.27815  1.000 14.60481  ? 270 ASP A H    1 
ATOM   4221 H HA   . ASP A 1 278 ? 6.56522   -7.13179  -8.71047  1.000 13.99361  ? 270 ASP A HA   1 
ATOM   4222 H HB2  . ASP A 1 278 ? 4.92841   -7.97006  -10.11084 1.000 17.72248  ? 270 ASP A HB2  1 
ATOM   4223 H HB3  . ASP A 1 278 ? 4.60083   -8.41424  -8.62060  1.000 17.72248  ? 270 ASP A HB3  1 
ATOM   4224 N N    . LEU A 1 279 ? 6.46836   -4.39768  -9.12026  1.000 12.88190  ? 271 LEU A N    1 
ATOM   4225 C CA   . LEU A 1 279 ? 6.76615   -3.26594  -9.99098  1.000 9.69788   ? 271 LEU A CA   1 
ATOM   4226 C C    . LEU A 1 279 ? 7.80678   -3.63676  -11.04287 1.000 13.23314  ? 271 LEU A C    1 
ATOM   4227 O O    . LEU A 1 279 ? 7.81743   -3.07231  -12.14489 1.000 12.96270  ? 271 LEU A O    1 
ATOM   4228 C CB   . LEU A 1 279 ? 7.24795   -2.09294  -9.14886  1.000 12.49583  ? 271 LEU A CB   1 
ATOM   4229 C CG   . LEU A 1 279 ? 7.60237   -0.80921  -9.87740  1.000 12.12223  ? 271 LEU A CG   1 
ATOM   4230 C CD1  . LEU A 1 279 ? 6.40083   -0.25345  -10.63569 1.000 15.75478  ? 271 LEU A CD1  1 
ATOM   4231 C CD2  . LEU A 1 279 ? 8.16043   0.22038   -8.89953  1.000 13.15866  ? 271 LEU A CD2  1 
ATOM   4232 H H    . LEU A 1 279 ? 6.72300   -4.30842  -8.30369  1.000 15.47531  ? 271 LEU A H    1 
ATOM   4233 H HA   . LEU A 1 279 ? 5.95980   -2.99230  -10.45554 1.000 11.65448  ? 271 LEU A HA   1 
ATOM   4234 H HB2  . LEU A 1 279 ? 6.54575   -1.87291  -8.51688  1.000 15.01202  ? 271 LEU A HB2  1 
ATOM   4235 H HB3  . LEU A 1 279 ? 8.04498   -2.37595  -8.67394  1.000 15.01202  ? 271 LEU A HB3  1 
ATOM   4236 H HG   . LEU A 1 279 ? 8.28947   -1.00233  -10.53428 1.000 14.56370  ? 271 LEU A HG   1 
ATOM   4237 H HD11 . LEU A 1 279 ? 6.65046   0.58706   -11.05059 1.000 18.92275  ? 271 LEU A HD11 1 
ATOM   4238 H HD12 . LEU A 1 279 ? 6.13385   -0.89157  -11.31571 1.000 18.92275  ? 271 LEU A HD12 1 
ATOM   4239 H HD13 . LEU A 1 279 ? 5.67205   -0.11070  -10.01167 1.000 18.92275  ? 271 LEU A HD13 1 
ATOM   4240 H HD21 . LEU A 1 279 ? 8.36808   1.03516   -9.38319  1.000 15.80742  ? 271 LEU A HD21 1 
ATOM   4241 H HD22 . LEU A 1 279 ? 7.49495   0.40114   -8.21735  1.000 15.80742  ? 271 LEU A HD22 1 
ATOM   4242 H HD23 . LEU A 1 279 ? 8.96479   -0.13580  -8.49083  1.000 15.80742  ? 271 LEU A HD23 1 
ATOM   4243 N N    . PHE A 1 280 ? 8.70065   -4.55905  -10.71934 1.000 14.49404  ? 272 PHE A N    1 
ATOM   4244 C CA   . PHE A 1 280 ? 9.70209   -5.02276  -11.66571 1.000 17.26632  ? 272 PHE A CA   1 
ATOM   4245 C C    . PHE A 1 280 ? 9.27547   -6.36510  -12.23389 1.000 17.08887  ? 272 PHE A C    1 
ATOM   4246 O O    . PHE A 1 280 ? 8.79578   -7.23807  -11.50496 1.000 18.46335  ? 272 PHE A O    1 
ATOM   4247 C CB   . PHE A 1 280 ? 11.08643  -5.15696  -11.02189 1.000 12.09258  ? 272 PHE A CB   1 
ATOM   4248 C CG   . PHE A 1 280 ? 11.78099  -3.84193  -10.82036 1.000 12.24429  ? 272 PHE A CG   1 
ATOM   4249 C CD1  . PHE A 1 280 ? 12.43875  -3.23148  -11.87207 1.000 12.48901  ? 272 PHE A CD1  1 
ATOM   4250 C CD2  . PHE A 1 280 ? 11.74386  -3.20133  -9.58619  1.000 16.55643  ? 272 PHE A CD2  1 
ATOM   4251 C CE1  . PHE A 1 280 ? 13.06286  -2.02555  -11.69242 1.000 15.25002  ? 272 PHE A CE1  1 
ATOM   4252 C CE2  . PHE A 1 280 ? 12.36129  -1.99224  -9.40482  1.000 14.28690  ? 272 PHE A CE2  1 
ATOM   4253 C CZ   . PHE A 1 280 ? 13.01058  -1.39614  -10.46491 1.000 14.64320  ? 272 PHE A CZ   1 
ATOM   4254 H H    . PHE A 1 280 ? 8.74759   -4.93588  -9.94772  1.000 17.40987  ? 272 PHE A H    1 
ATOM   4255 H HA   . PHE A 1 280 ? 9.77722   -4.37585  -12.38457 1.000 20.73660  ? 272 PHE A HA   1 
ATOM   4256 H HB2  . PHE A 1 280 ? 10.98840  -5.57772  -10.15341 1.000 14.52812  ? 272 PHE A HB2  1 
ATOM   4257 H HB3  . PHE A 1 280 ? 11.64630  -5.70436  -11.59443 1.000 14.52812  ? 272 PHE A HB3  1 
ATOM   4258 H HD1  . PHE A 1 280 ? 12.45755  -3.64202  -12.70634 1.000 15.00384  ? 272 PHE A HD1  1 
ATOM   4259 H HD2  . PHE A 1 280 ? 11.29439  -3.59879  -8.87563  1.000 19.88474  ? 272 PHE A HD2  1 
ATOM   4260 H HE1  . PHE A 1 280 ? 13.52221  -1.63044  -12.39797 1.000 18.31704  ? 272 PHE A HE1  1 
ATOM   4261 H HE2  . PHE A 1 280 ? 12.34268  -1.57663  -8.57306  1.000 17.16130  ? 272 PHE A HE2  1 
ATOM   4262 H HZ   . PHE A 1 280 ? 13.41515  -0.56632  -10.35256 1.000 17.58886  ? 272 PHE A HZ   1 
ATOM   4263 N N    . LEU A 1 281 ? 9.42268   -6.50292  -13.54455 1.000 12.80885  ? 273 LEU A N    1 
ATOM   4264 C CA   . LEU A 1 281 ? 9.20644   -7.74734  -14.26592 1.000 13.61376  ? 273 LEU A CA   1 
ATOM   4265 C C    . LEU A 1 281 ? 10.53897  -8.24716  -14.81153 1.000 16.98160  ? 273 LEU A C    1 
ATOM   4266 O O    . LEU A 1 281 ? 11.32060  -7.46352  -15.36766 1.000 16.86504  ? 273 LEU A O    1 
ATOM   4267 C CB   . LEU A 1 281 ? 8.22550   -7.53583  -15.42150 1.000 15.91337  ? 273 LEU A CB   1 
ATOM   4268 C CG   . LEU A 1 281 ? 6.82606   -7.04642  -15.08024 1.000 19.82329  ? 273 LEU A CG   1 
ATOM   4269 C CD1  . LEU A 1 281 ? 6.07447   -6.69296  -16.34803 1.000 24.95263  ? 273 LEU A CD1  1 
ATOM   4270 C CD2  . LEU A 1 281 ? 6.07342   -8.11319  -14.27857 1.000 22.93907  ? 273 LEU A CD2  1 
ATOM   4271 H H    . LEU A 1 281 ? 9.65875   -5.85777  -14.06190 1.000 15.38764  ? 273 LEU A H    1 
ATOM   4272 H HA   . LEU A 1 281 ? 8.84378   -8.41573  -13.66373 1.000 16.35353  ? 273 LEU A HA   1 
ATOM   4273 H HB2  . LEU A 1 281 ? 8.61281   -6.87973  -16.02185 1.000 19.11306  ? 273 LEU A HB2  1 
ATOM   4274 H HB3  . LEU A 1 281 ? 8.12124   -8.38427  -15.87996 1.000 19.11306  ? 273 LEU A HB3  1 
ATOM   4275 H HG   . LEU A 1 281 ? 6.88475   -6.24762  -14.53309 1.000 23.80497  ? 273 LEU A HG   1 
ATOM   4276 H HD11 . LEU A 1 281 ? 5.17669   -6.40961  -16.11433 1.000 29.96018  ? 273 LEU A HD11 1 
ATOM   4277 H HD12 . LEU A 1 281 ? 6.54091   -5.97344  -16.80149 1.000 29.96018  ? 273 LEU A HD12 1 
ATOM   4278 H HD13 . LEU A 1 281 ? 6.03599   -7.47489  -16.92075 1.000 29.96018  ? 273 LEU A HD13 1 
ATOM   4279 H HD21 . LEU A 1 281 ? 5.16741   -7.80643  -14.11746 1.000 27.54391  ? 273 LEU A HD21 1 
ATOM   4280 H HD22 . LEU A 1 281 ? 6.05755   -8.93843  -14.78809 1.000 27.54391  ? 273 LEU A HD22 1 
ATOM   4281 H HD23 . LEU A 1 281 ? 6.52987   -8.25437  -13.43440 1.000 27.54391  ? 273 LEU A HD23 1 
ATOM   4282 N N    . ARG A 1 282 ? 10.80414  -9.54099  -14.63585 1.000 13.60179  ? 274 ARG A N    1 
ATOM   4283 C CA   . ARG A 1 282 ? 11.90070  -10.22909 -15.31276 1.000 12.86058  ? 274 ARG A CA   1 
ATOM   4284 C C    . ARG A 1 282 ? 11.25799  -10.94902 -16.49142 1.000 12.64373  ? 274 ARG A C    1 
ATOM   4285 O O    . ARG A 1 282 ? 10.65504  -12.01186 -16.32177 1.000 15.14375  ? 274 ARG A O    1 
ATOM   4286 C CB   . ARG A 1 282 ? 12.61852  -11.19409 -14.37634 1.000 10.74428  ? 274 ARG A CB   1 
ATOM   4287 C CG   . ARG A 1 282 ? 13.75685  -11.97789 -15.02017 1.000 10.73389  ? 274 ARG A CG   1 
ATOM   4288 C CD   . ARG A 1 282 ? 15.01582  -11.11169 -15.16176 1.000 15.16782  ? 274 ARG A CD   1 
ATOM   4289 N NE   . ARG A 1 282 ? 15.57134  -10.76127 -13.85607 1.000 14.40640  ? 274 ARG A NE   1 
ATOM   4290 C CZ   . ARG A 1 282 ? 16.64689  -9.99876  -13.67166 1.000 20.18312  ? 274 ARG A CZ   1 
ATOM   4291 N NH1  . ARG A 1 282 ? 17.28073  -9.48693  -14.71088 1.000 17.69771  ? 274 ARG A NH1  1 
ATOM   4292 N NH2  . ARG A 1 282 ? 17.08107  -9.72649  -12.44653 1.000 16.23947  ? 274 ARG A NH2  1 
ATOM   4293 H H    . ARG A 1 282 ? 10.35039  -10.05392 -14.11564 1.000 16.33917  ? 274 ARG A H    1 
ATOM   4294 H HA   . ARG A 1 282 ? 12.56526  -9.59577  -15.62607 1.000 15.44972  ? 274 ARG A HA   1 
ATOM   4295 H HB2  . ARG A 1 282 ? 12.99327  -10.68690 -13.63930 1.000 12.91016  ? 274 ARG A HB2  1 
ATOM   4296 H HB3  . ARG A 1 282 ? 11.97334  -11.83692 -14.04256 1.000 12.91016  ? 274 ARG A HB3  1 
ATOM   4297 H HG2  . ARG A 1 282 ? 13.97346  -12.74487 -14.46726 1.000 12.89769  ? 274 ARG A HG2  1 
ATOM   4298 H HG3  . ARG A 1 282 ? 13.48645  -12.27190 -15.90411 1.000 12.89769  ? 274 ARG A HG3  1 
ATOM   4299 H HD2  . ARG A 1 282 ? 15.68925  -11.60206 -15.65869 1.000 18.21841  ? 274 ARG A HD2  1 
ATOM   4300 H HD3  . ARG A 1 282 ? 14.79098  -10.29149 -15.62825 1.000 18.21841  ? 274 ARG A HD3  1 
ATOM   4301 H HE   . ARG A 1 282 ? 15.17542  -11.06944 -13.15758 1.000 17.30470  ? 274 ARG A HE   1 
ATOM   4302 H HH11 . ARG A 1 282 ? 16.99879  -9.64609  -15.50761 1.000 21.25427  ? 274 ARG A HH11 1 
ATOM   4303 H HH12 . ARG A 1 282 ? 17.97547  -8.99444  -14.59096 1.000 21.25427  ? 274 ARG A HH12 1 
ATOM   4304 H HH21 . ARG A 1 282 ? 16.66656  -10.04367 -11.76303 1.000 19.50438  ? 274 ARG A HH21 1 
ATOM   4305 H HH22 . ARG A 1 282 ? 17.77676  -9.23299  -12.33665 1.000 19.50438  ? 274 ARG A HH22 1 
ATOM   4306 N N    . HIS A 1 283 ? 11.33331  -10.34500 -17.68426 1.000 14.34555  ? 275 HIS A N    1 
ATOM   4307 C CA   . HIS A 1 283 ? 10.63627  -10.92752 -18.83351 1.000 19.44303  ? 275 HIS A CA   1 
ATOM   4308 C C    . HIS A 1 283 ? 11.44628  -12.03256 -19.50412 1.000 19.39994  ? 275 HIS A C    1 
ATOM   4309 O O    . HIS A 1 283 ? 10.87988  -12.86368 -20.21968 1.000 22.90980  ? 275 HIS A O    1 
ATOM   4310 C CB   . HIS A 1 283 ? 10.25617  -9.83596  -19.84900 1.000 19.82669  ? 275 HIS A CB   1 
ATOM   4311 C CG   . HIS A 1 283 ? 11.42718  -9.08280  -20.41659 1.000 14.47558  ? 275 HIS A CG   1 
ATOM   4312 N ND1  . HIS A 1 283 ? 12.31314  -9.64066  -21.31173 1.000 16.44313  ? 275 HIS A ND1  1 
ATOM   4313 C CD2  . HIS A 1 283 ? 11.83389  -7.80417  -20.23294 1.000 16.19458  ? 275 HIS A CD2  1 
ATOM   4314 C CE1  . HIS A 1 283 ? 13.23373  -8.74772  -21.63344 1.000 15.78292  ? 275 HIS A CE1  1 
ATOM   4315 N NE2  . HIS A 1 283 ? 12.96075  -7.62173  -20.99867 1.000 14.06062  ? 275 HIS A NE2  1 
ATOM   4316 H H    . HIS A 1 283 ? 11.76772  -9.62086  -17.84705 1.000 17.23168  ? 275 HIS A H    1 
ATOM   4317 H HA   . HIS A 1 283 ? 9.80404   -11.32182 -18.52883 1.000 23.34866  ? 275 HIS A HA   1 
ATOM   4318 H HB2  . HIS A 1 283 ? 9.78766   -10.25172 -20.58964 1.000 23.80905  ? 275 HIS A HB2  1 
ATOM   4319 H HB3  . HIS A 1 283 ? 9.67812   -9.19247  -19.41006 1.000 23.80905  ? 275 HIS A HB3  1 
ATOM   4320 H HD2  . HIS A 1 283 ? 11.42676  -7.16822  -19.69006 1.000 19.45052  ? 275 HIS A HD2  1 
ATOM   4321 H HE1  . HIS A 1 283 ? 13.95101  -8.88833  -22.20845 1.000 18.95653  ? 275 HIS A HE1  1 
ATOM   4322 N N    . THR A 1 284 ? 12.74207  -12.09298 -19.23884 1.000 16.68330  ? 276 THR A N    1 
ATOM   4323 C CA   . THR A 1 284 ? 13.64131  -13.09600 -19.78892 1.000 14.48836  ? 276 THR A CA   1 
ATOM   4324 C C    . THR A 1 284 ? 14.66327  -13.44629 -18.71855 1.000 17.92701  ? 276 THR A C    1 
ATOM   4325 O O    . THR A 1 284 ? 15.07964  -12.58628 -17.94003 1.000 17.11965  ? 276 THR A O    1 
ATOM   4326 C CB   . THR A 1 284 ? 14.36495  -12.59145 -21.04481 1.000 21.69454  ? 276 THR A CB   1 
ATOM   4327 O OG1  . THR A 1 284 ? 13.39654  -12.15818 -22.00447 1.000 21.93655  ? 276 THR A OG1  1 
ATOM   4328 C CG2  . THR A 1 284 ? 15.23415  -13.68891 -21.64494 1.000 27.72741  ? 276 THR A CG2  1 
ATOM   4329 H H    . THR A 1 284 ? 13.14389  -11.53843 -18.71863 1.000 20.03698  ? 276 THR A H    1 
ATOM   4330 H HA   . THR A 1 284 ? 13.14230  -13.89089 -20.03393 1.000 17.40305  ? 276 THR A HA   1 
ATOM   4331 H HB   . THR A 1 284 ? 14.94447  -11.84886 -20.81325 1.000 26.05046  ? 276 THR A HB   1 
ATOM   4332 H HG1  . THR A 1 284 ? 12.70726  -11.88138 -21.61220 1.000 26.34088  ? 276 THR A HG1  1 
ATOM   4333 H HG21 . THR A 1 284 ? 15.65502  -13.37089 -22.45896 1.000 33.28991  ? 276 THR A HG21 1 
ATOM   4334 H HG22 . THR A 1 284 ? 15.92413  -13.94779 -21.01422 1.000 33.28991  ? 276 THR A HG22 1 
ATOM   4335 H HG23 . THR A 1 284 ? 14.69125  -14.46515 -21.85377 1.000 33.28991  ? 276 THR A HG23 1 
ATOM   4336 N N    . THR A 1 285 ? 15.07494  -14.70841 -18.69136 1.000 17.22394  ? 277 THR A N    1 
ATOM   4337 C CA   . THR A 1 285 ? 16.07705  -15.13872 -17.72637 1.000 16.88466  ? 277 THR A CA   1 
ATOM   4338 C C    . THR A 1 285 ? 17.43352  -14.52314 -18.04713 1.000 21.97141  ? 277 THR A C    1 
ATOM   4339 O O    . THR A 1 285 ? 17.83524  -14.43190 -19.20990 1.000 20.35278  ? 277 THR A O    1 
ATOM   4340 C CB   . THR A 1 285 ? 16.16445  -16.66193 -17.69841 1.000 19.70876  ? 277 THR A CB   1 
ATOM   4341 O OG1  . THR A 1 285 ? 14.95112  -17.17094 -17.12578 1.000 18.71808  ? 277 THR A OG1  1 
ATOM   4342 C CG2  . THR A 1 285 ? 17.35103  -17.11631 -16.86264 1.000 22.94723  ? 277 THR A CG2  1 
ATOM   4343 H H    . THR A 1 285 ? 14.79255  -15.32889 -19.21563 1.000 20.68575  ? 277 THR A H    1 
ATOM   4344 H HA   . THR A 1 285 ? 15.82237  -14.84108 -16.83899 1.000 20.27861  ? 277 THR A HA   1 
ATOM   4345 H HB   . THR A 1 285 ? 16.28468  -17.00946 -18.59600 1.000 23.66753  ? 277 THR A HB   1 
ATOM   4346 H HG1  . THR A 1 285 ? 15.11340  -17.86137 -16.67570 1.000 22.47872  ? 277 THR A HG1  1 
ATOM   4347 H HG21 . THR A 1 285 ? 17.31251  -18.07585 -16.72592 1.000 27.55370  ? 277 THR A HG21 1 
ATOM   4348 H HG22 . THR A 1 285 ? 18.17985  -16.89593 -17.31584 1.000 27.55370  ? 277 THR A HG22 1 
ATOM   4349 H HG23 . THR A 1 285 ? 17.33727  -16.67450 -15.99920 1.000 27.55370  ? 277 THR A HG23 1 
ATOM   4350 N N    . ALA A 1 286 ? 18.13545  -14.08867 -17.00376 1.000 18.93040  ? 278 ALA A N    1 
ATOM   4351 C CA   . ALA A 1 286 ? 19.41504  -13.40367 -17.14825 1.000 22.62318  ? 278 ALA A CA   1 
ATOM   4352 C C    . ALA A 1 286 ? 20.52270  -14.16696 -16.42907 1.000 27.29013  ? 278 ALA A C    1 
ATOM   4353 O O    . ALA A 1 286 ? 20.28537  -15.17167 -15.75301 1.000 27.13023  ? 278 ALA A O    1 
ATOM   4354 C CB   . ALA A 1 286 ? 19.33446  -11.97369 -16.60719 1.000 29.83277  ? 278 ALA A CB   1 
ATOM   4355 H H    . ALA A 1 286 ? 17.88453  -14.18173 -16.18646 1.000 22.73351  ? 278 ALA A H    1 
ATOM   4356 H HA   . ALA A 1 286 ? 19.62912  -13.37735 -18.09396 1.000 27.16484  ? 278 ALA A HA   1 
ATOM   4357 H HB1  . ALA A 1 286 ? 20.16161  -11.51090 -16.81350 1.000 35.81635  ? 278 ALA A HB1  1 
ATOM   4358 H HB2  . ALA A 1 286 ? 18.58745  -11.51891 -17.02676 1.000 35.81635  ? 278 ALA A HB2  1 
ATOM   4359 H HB3  . ALA A 1 286 ? 19.20448  -12.00639 -15.64649 1.000 35.81635  ? 278 ALA A HB3  1 
ATOM   4360 N N    . ILE A 1 287 ? 21.74585  -13.65470 -16.57504 1.000 47.33326  ? 279 ILE A N    1 
ATOM   4361 C CA   . ILE A 1 287 ? 22.88285  -14.11316 -15.78237 1.000 46.93197  ? 279 ILE A CA   1 
ATOM   4362 C C    . ILE A 1 287 ? 22.80050  -13.48383 -14.39703 1.000 36.23777  ? 279 ILE A C    1 
ATOM   4363 O O    . ILE A 1 287 ? 22.61551  -12.26685 -14.26458 1.000 50.88284  ? 279 ILE A O    1 
ATOM   4364 C CB   . ILE A 1 287 ? 24.20933  -13.75321 -16.47151 1.000 45.12543  ? 279 ILE A CB   1 
ATOM   4365 C CG1  . ILE A 1 287 ? 24.20682  -14.22891 -17.92469 1.000 46.17090  ? 279 ILE A CG1  1 
ATOM   4366 C CG2  . ILE A 1 287 ? 25.38907  -14.33555 -15.70078 1.000 48.01567  ? 279 ILE A CG2  1 
ATOM   4367 C CD1  . ILE A 1 287 ? 25.12358  -13.42661 -18.83007 1.000 42.13045  ? 279 ILE A CD1  1 
ATOM   4368 N N    . LYS A 1 288 ? 22.93735  -14.30870 -13.35916 1.000 35.92303  ? 280 LYS A N    1 
ATOM   4369 C CA   . LYS A 1 288 ? 22.88703  -13.79470 -11.99530 1.000 48.48546  ? 280 LYS A CA   1 
ATOM   4370 C C    . LYS A 1 288 ? 24.02743  -12.81142 -11.76252 1.000 51.66200  ? 280 LYS A C    1 
ATOM   4371 O O    . LYS A 1 288 ? 25.18985  -13.11414 -12.04413 1.000 35.73263  ? 280 LYS A O    1 
ATOM   4372 C CB   . LYS A 1 288 ? 22.96068  -14.94357 -10.99014 1.000 45.45813  ? 280 LYS A CB   1 
ATOM   4373 C CG   . LYS A 1 288 ? 22.58084  -14.54704 -9.57517  1.000 52.45302  ? 280 LYS A CG   1 
ATOM   4374 C CD   . LYS A 1 288 ? 22.93972  -15.63855 -8.58237  1.000 51.43999  ? 280 LYS A CD   1 
ATOM   4375 C CE   . LYS A 1 288 ? 21.70032  -16.32379 -8.05243  1.000 55.33243  ? 280 LYS A CE   1 
ATOM   4376 N NZ   . LYS A 1 288 ? 20.66581  -15.32869 -7.65090  1.000 63.31273  ? 280 LYS A NZ   1 
ATOM   4377 N N    . SER A 1 289 ? 23.69025  -11.62450 -11.25656 1.000 40.82692  ? 281 SER A N    1 
ATOM   4378 C CA   . SER A 1 289 ? 24.68238  -10.57850 -11.02919 1.000 34.24669  ? 281 SER A CA   1 
ATOM   4379 C C    . SER A 1 289 ? 24.09858  -9.45051  -10.18825 1.000 48.57690  ? 281 SER A C    1 
ATOM   4380 O O    . SER A 1 289 ? 23.01067  -8.94616  -10.48061 1.000 40.91013  ? 281 SER A O    1 
ATOM   4381 C CB   . SER A 1 289 ? 25.19751  -10.02340 -12.35889 1.000 39.43363  ? 281 SER A CB   1 
ATOM   4382 O OG   . SER A 1 289 ? 24.15821  -9.36290  -13.05853 1.000 39.63025  ? 281 SER A OG   1 
ATOM   4383 N N    . GLN A 1 290 ? 24.81422  -9.03987  -9.15013  1.000 35.11737  ? 282 GLN A N    1 
ATOM   4384 C CA   . GLN A 1 290 ? 24.33632  -7.97266  -8.28206  1.000 35.91202  ? 282 GLN A CA   1 
ATOM   4385 C C    . GLN A 1 290 ? 25.41977  -6.94049  -8.01848  1.000 20.38464  ? 282 GLN A C    1 
ATOM   4386 O O    . GLN A 1 290 ? 25.27916  -6.11446  -7.10000  1.000 22.60006  ? 282 GLN A O    1 
ATOM   4387 C CB   . GLN A 1 290 ? 23.83464  -8.55095  -6.95553  1.000 41.21758  ? 282 GLN A CB   1 
ATOM   4388 C CG   . GLN A 1 290 ? 22.58214  -9.40249  -7.08902  1.000 44.33398  ? 282 GLN A CG   1 
ATOM   4389 C CD   . GLN A 1 290 ? 22.33535  -10.26957 -5.87328  1.000 57.57540  ? 282 GLN A CD   1 
ATOM   4390 O OE1  . GLN A 1 290 ? 23.15999  -11.11358 -5.52017  1.000 78.94788  ? 282 GLN A OE1  1 
ATOM   4391 N NE2  . GLN A 1 290 ? 21.19387  -10.06621 -5.22414  1.000 49.79277  ? 282 GLN A NE2  1 
ATOM   4392 N N    . VAL A 1 299 ? 30.20650  -9.41978  -14.68917 1.000 37.30389  ? 291 VAL A N    1 
ATOM   4393 C CA   . VAL A 1 299 ? 29.05699  -9.60371  -15.57033 1.000 44.29390  ? 291 VAL A CA   1 
ATOM   4394 C C    . VAL A 1 299 ? 28.59476  -8.23423  -16.06941 1.000 45.26314  ? 291 VAL A C    1 
ATOM   4395 O O    . VAL A 1 299 ? 28.45286  -7.29549  -15.28253 1.000 38.08712  ? 291 VAL A O    1 
ATOM   4396 C CB   . VAL A 1 299 ? 27.91346  -10.34546 -14.86096 1.000 61.22290  ? 291 VAL A CB   1 
ATOM   4397 C CG1  . VAL A 1 299 ? 26.84015  -10.75568 -15.86974 1.000 59.11885  ? 291 VAL A CG1  1 
ATOM   4398 C CG2  . VAL A 1 299 ? 28.44639  -11.56370 -14.12095 1.000 45.51580  ? 291 VAL A CG2  1 
ATOM   4399 H HA   . VAL A 1 299 ? 29.31553  -10.14899 -16.32975 1.000 53.16971  ? 291 VAL A HA   1 
ATOM   4400 H HB   . VAL A 1 299 ? 27.50814  -9.75123  -14.21018 1.000 73.48450  ? 291 VAL A HB   1 
ATOM   4401 H HG11 . VAL A 1 299 ? 26.13260  -11.22789 -15.40358 1.000 70.95964  ? 291 VAL A HG11 1 
ATOM   4402 H HG12 . VAL A 1 299 ? 26.48329  -9.95902  -16.29269 1.000 70.95964  ? 291 VAL A HG12 1 
ATOM   4403 H HG13 . VAL A 1 299 ? 27.23951  -11.33432 -16.53801 1.000 70.95964  ? 291 VAL A HG13 1 
ATOM   4404 H HG21 . VAL A 1 299 ? 27.70732  -12.01779 -13.68683 1.000 54.63599  ? 291 VAL A HG21 1 
ATOM   4405 H HG22 . VAL A 1 299 ? 28.87209  -12.15879 -14.75778 1.000 54.63599  ? 291 VAL A HG22 1 
ATOM   4406 H HG23 . VAL A 1 299 ? 29.09157  -11.27296 -13.45754 1.000 54.63599  ? 291 VAL A HG23 1 
ATOM   4407 N N    . ASN A 1 300 ? 28.35632  -8.11659  -17.37409 1.000 31.95579  ? 292 ASN A N    1 
ATOM   4408 C CA   . ASN A 1 300 ? 27.96496  -6.83176  -17.93639 1.000 26.73582  ? 292 ASN A CA   1 
ATOM   4409 C C    . ASN A 1 300 ? 26.54341  -6.47626  -17.51510 1.000 32.41916  ? 292 ASN A C    1 
ATOM   4410 O O    . ASN A 1 300 ? 25.66901  -7.34183  -17.43465 1.000 32.10151  ? 292 ASN A O    1 
ATOM   4411 C CB   . ASN A 1 300 ? 28.06635  -6.85240  -19.46036 1.000 31.08048  ? 292 ASN A CB   1 
ATOM   4412 C CG   . ASN A 1 300 ? 27.77784  -5.49405  -20.07015 1.000 37.17939  ? 292 ASN A CG   1 
ATOM   4413 O OD1  . ASN A 1 300 ? 26.64803  -5.19740  -20.44106 1.000 35.57426  ? 292 ASN A OD1  1 
ATOM   4414 N ND2  . ASN A 1 300 ? 28.80044  -4.65334  -20.15717 1.000 56.14959  ? 292 ASN A ND2  1 
ATOM   4415 H H    . ASN A 1 300 ? 28.41381  -8.75715  -17.94504 1.000 38.36397  ? 292 ASN A H    1 
ATOM   4416 H HA   . ASN A 1 300 ? 28.56641  -6.14592  -17.60657 1.000 32.10001  ? 292 ASN A HA   1 
ATOM   4417 N N    . ILE A 1 301 ? 26.31590  -5.18815  -17.24716 1.000 26.25855  ? 293 ILE A N    1 
ATOM   4418 C CA   . ILE A 1 301 ? 25.01930  -4.74275  -16.74403 1.000 24.22781  ? 293 ILE A CA   1 
ATOM   4419 C C    . ILE A 1 301 ? 23.92497  -4.85317  -17.78906 1.000 21.82581  ? 293 ILE A C    1 
ATOM   4420 O O    . ILE A 1 301 ? 22.73755  -4.89328  -17.42580 1.000 19.81801  ? 293 ILE A O    1 
ATOM   4421 C CB   . ILE A 1 301 ? 25.15007  -3.30455  -16.21556 1.000 25.35962  ? 293 ILE A CB   1 
ATOM   4422 C CG1  . ILE A 1 301 ? 23.86150  -2.85603  -15.52248 1.000 27.15992  ? 293 ILE A CG1  1 
ATOM   4423 C CG2  . ILE A 1 301 ? 25.51136  -2.33950  -17.34929 1.000 28.33671  ? 293 ILE A CG2  1 
ATOM   4424 C CD1  . ILE A 1 301 ? 23.99522  -1.56203  -14.75952 1.000 30.76708  ? 293 ILE A CD1  1 
ATOM   4425 H H    . ILE A 1 301 ? 26.89235  -4.55794  -17.34788 1.000 31.52728  ? 293 ILE A H    1 
ATOM   4426 H HA   . ILE A 1 301 ? 24.75360  -5.31966  -16.01090 1.000 29.09040  ? 293 ILE A HA   1 
ATOM   4427 H HB   . ILE A 1 301 ? 25.86629  -3.29499  -15.56146 1.000 30.44857  ? 293 ILE A HB   1 
ATOM   4428 H HG12 . ILE A 1 301 ? 23.17332  -2.73257  -16.19484 1.000 32.60892  ? 293 ILE A HG12 1 
ATOM   4429 H HG13 . ILE A 1 301 ? 23.59120  -3.54311  -14.89338 1.000 32.60892  ? 293 ILE A HG13 1 
ATOM   4430 H HG21 . ILE A 1 301 ? 25.72141  -1.47164  -16.97036 1.000 34.02107  ? 293 ILE A HG21 1 
ATOM   4431 H HG22 . ILE A 1 301 ? 26.28095  -2.68705  -17.82663 1.000 34.02107  ? 293 ILE A HG22 1 
ATOM   4432 H HG23 . ILE A 1 301 ? 24.75516  -2.26305  -17.95195 1.000 34.02107  ? 293 ILE A HG23 1 
ATOM   4433 H HD11 . ILE A 1 301 ? 23.15313  -1.36628  -14.31967 1.000 36.93752  ? 293 ILE A HD11 1 
ATOM   4434 H HD12 . ILE A 1 301 ? 24.69935  -1.65616  -14.09904 1.000 36.93752  ? 293 ILE A HD12 1 
ATOM   4435 H HD13 . ILE A 1 301 ? 24.21719  -0.85074  -15.38056 1.000 36.93752  ? 293 ILE A HD13 1 
ATOM   4436 N N    . THR A 1 302 ? 24.27872  -4.95375  -19.07583 1.000 19.25836  ? 294 THR A N    1 
ATOM   4437 C CA   . THR A 1 302 ? 23.25837  -5.14347  -20.10207 1.000 17.99772  ? 294 THR A CA   1 
ATOM   4438 C C    . THR A 1 302 ? 22.45075  -6.41737  -19.86238 1.000 17.41131  ? 294 THR A C    1 
ATOM   4439 O O    . THR A 1 302 ? 21.30145  -6.51654  -20.30440 1.000 18.15547  ? 294 THR A O    1 
ATOM   4440 C CB   . THR A 1 302 ? 23.87419  -5.21626  -21.50244 1.000 18.86515  ? 294 THR A CB   1 
ATOM   4441 O OG1  . THR A 1 302 ? 24.82256  -6.28827  -21.54286 1.000 26.74093  ? 294 THR A OG1  1 
ATOM   4442 C CG2  . THR A 1 302 ? 24.54921  -3.93965  -21.86444 1.000 29.84776  ? 294 THR A CG2  1 
ATOM   4443 H H    . THR A 1 302 ? 25.08551  -4.91584  -19.37123 1.000 23.12705  ? 294 THR A H    1 
ATOM   4444 H HA   . THR A 1 302 ? 22.67249  -4.37118  -20.06722 1.000 21.61428  ? 294 THR A HA   1 
ATOM   4445 H HB   . THR A 1 302 ? 23.17256  -5.37095  -22.15412 1.000 22.65520  ? 294 THR A HB   1 
ATOM   4446 H HG1  . THR A 1 302 ? 25.06298  -6.42944  -22.33524 1.000 32.10614  ? 294 THR A HG1  1 
ATOM   4447 H HG21 . THR A 1 302 ? 25.15062  -4.08271  -22.61193 1.000 35.83434  ? 294 THR A HG21 1 
ATOM   4448 H HG22 . THR A 1 302 ? 23.88892  -3.27452  -22.11449 1.000 35.83434  ? 294 THR A HG22 1 
ATOM   4449 H HG23 . THR A 1 302 ? 25.05937  -3.60826  -21.10891 1.000 35.83434  ? 294 THR A HG23 1 
ATOM   4450 N N    . SER A 1 303 ? 23.04292  -7.40423  -19.18940 1.000 18.00383  ? 295 SER A N    1 
ATOM   4451 C CA   . SER A 1 303 ? 22.32589  -8.64546  -18.91584 1.000 19.95720  ? 295 SER A CA   1 
ATOM   4452 C C    . SER A 1 303 ? 21.10248  -8.37932  -18.05564 1.000 19.77939  ? 295 SER A C    1 
ATOM   4453 O O    . SER A 1 303 ? 20.07165  -9.04782  -18.19415 1.000 19.63951  ? 295 SER A O    1 
ATOM   4454 C CB   . SER A 1 303 ? 23.25521  -9.63756  -18.22186 1.000 24.72145  ? 295 SER A CB   1 
ATOM   4455 O OG   . SER A 1 303 ? 22.63680  -10.90351 -18.10115 1.000 51.05065  ? 295 SER A OG   1 
ATOM   4456 H H    . SER A 1 303 ? 23.84693  -7.38008  -18.88512 1.000 21.62161  ? 295 SER A H    1 
ATOM   4457 H HA   . SER A 1 303 ? 22.03435  -9.03784  -19.75366 1.000 23.96566  ? 295 SER A HA   1 
ATOM   4458 H HB2  . SER A 1 303 ? 24.06623  -9.73062  -18.74577 1.000 29.68276  ? 295 SER A HB2  1 
ATOM   4459 H HB3  . SER A 1 303 ? 23.46874  -9.30435  -17.33627 1.000 29.68276  ? 295 SER A HB3  1 
ATOM   4460 H HG   . SER A 1 303 ? 23.15564  -11.44129 -17.71751 1.000 61.27780  ? 295 SER A HG   1 
ATOM   4461 N N    . GLN A 1 304 ? 21.20863  -7.40154  -17.15411 1.000 16.90889  ? 296 GLN A N    1 
ATOM   4462 C CA   . GLN A 1 304 ? 20.07290  -7.00696  -16.32928 1.000 12.91298  ? 296 GLN A CA   1 
ATOM   4463 C C    . GLN A 1 304 ? 19.12501  -6.10451  -17.11068 1.000 14.75923  ? 296 GLN A C    1 
ATOM   4464 O O    . GLN A 1 304 ? 17.91478  -6.36163  -17.17864 1.000 14.71481  ? 296 GLN A O    1 
ATOM   4465 C CB   . GLN A 1 304 ? 20.57199  -6.29914  -15.06036 1.000 14.35916  ? 296 GLN A CB   1 
ATOM   4466 C CG   . GLN A 1 304 ? 21.30709  -7.20798  -14.06649 1.000 15.85529  ? 296 GLN A CG   1 
ATOM   4467 C CD   . GLN A 1 304 ? 20.37173  -7.92161  -13.11009 1.000 20.74275  ? 296 GLN A CD   1 
ATOM   4468 O OE1  . GLN A 1 304 ? 19.15000  -7.86305  -13.25273 1.000 15.39273  ? 296 GLN A OE1  1 
ATOM   4469 N NE2  . GLN A 1 304 ? 20.94244  -8.57751  -12.10908 1.000 25.69840  ? 296 GLN A NE2  1 
ATOM   4470 H H    . GLN A 1 304 ? 21.92665  -6.95315  -17.00251 1.000 20.30768  ? 296 GLN A H    1 
ATOM   4471 H HA   . GLN A 1 304 ? 19.58308  -7.79859  -16.05671 1.000 15.51260  ? 296 GLN A HA   1 
ATOM   4472 H HB2  . GLN A 1 304 ? 21.18589  -5.59499  -15.32151 1.000 17.24801  ? 296 GLN A HB2  1 
ATOM   4473 H HB3  . GLN A 1 304 ? 19.80815  -5.91906  -14.59885 1.000 17.24801  ? 296 GLN A HB3  1 
ATOM   4474 H HG2  . GLN A 1 304 ? 21.79972  -7.88169  -14.56078 1.000 19.04337  ? 296 GLN A HG2  1 
ATOM   4475 H HG3  . GLN A 1 304 ? 21.91848  -6.66945  -13.54010 1.000 19.04337  ? 296 GLN A HG3  1 
ATOM   4476 H HE21 . GLN A 1 304 ? 21.79883  -8.58143  -12.03036 1.000 30.85510  ? 296 GLN A HE21 1 
ATOM   4477 H HE22 . GLN A 1 304 ? 20.45625  -8.99902  -11.53852 1.000 30.85510  ? 296 GLN A HE22 1 
ATOM   4478 N N    . ILE A 1 305 ? 19.66893  -5.05019  -17.72642 1.000 13.63845  ? 297 ILE A N    1 
ATOM   4479 C CA   . ILE A 1 305 ? 18.83454  -4.06043  -18.40155 1.000 13.27165  ? 297 ILE A CA   1 
ATOM   4480 C C    . ILE A 1 305 ? 17.97842  -4.72370  -19.46806 1.000 14.72377  ? 297 ILE A C    1 
ATOM   4481 O O    . ILE A 1 305 ? 16.81154  -4.36489  -19.66560 1.000 16.71729  ? 297 ILE A O    1 
ATOM   4482 C CB   . ILE A 1 305 ? 19.71401  -2.94832  -19.00483 1.000 18.44132  ? 297 ILE A CB   1 
ATOM   4483 C CG1  . ILE A 1 305 ? 20.41454  -2.14858  -17.90221 1.000 15.49574  ? 297 ILE A CG1  1 
ATOM   4484 C CG2  . ILE A 1 305 ? 18.88594  -2.01794  -19.88007 1.000 17.94489  ? 297 ILE A CG2  1 
ATOM   4485 C CD1  . ILE A 1 305 ? 21.60025  -1.33351  -18.41862 1.000 20.70654  ? 297 ILE A CD1  1 
ATOM   4486 H H    . ILE A 1 305 ? 20.51256  -4.88800  -17.76630 1.000 16.38317  ? 297 ILE A H    1 
ATOM   4487 H HA   . ILE A 1 305 ? 18.24211  -3.66041  -17.74588 1.000 15.94300  ? 297 ILE A HA   1 
ATOM   4488 H HB   . ILE A 1 305 ? 20.38971  -3.37435  -19.55513 1.000 22.14661  ? 297 ILE A HB   1 
ATOM   4489 H HG12 . ILE A 1 305 ? 19.77774  -1.53315  -17.50645 1.000 18.61192  ? 297 ILE A HG12 1 
ATOM   4490 H HG13 . ILE A 1 305 ? 20.74451  -2.76337  -17.22838 1.000 18.61192  ? 297 ILE A HG13 1 
ATOM   4491 H HG21 . ILE A 1 305 ? 19.42453  -1.24778  -20.12023 1.000 21.55089  ? 297 ILE A HG21 1 
ATOM   4492 H HG22 . ILE A 1 305 ? 18.61533  -2.49482  -20.68023 1.000 21.55089  ? 297 ILE A HG22 1 
ATOM   4493 H HG23 . ILE A 1 305 ? 18.10260  -1.73220  -19.38446 1.000 21.55089  ? 297 ILE A HG23 1 
ATOM   4494 H HD11 . ILE A 1 305 ? 22.01262  -0.86905  -17.67356 1.000 24.86487  ? 297 ILE A HD11 1 
ATOM   4495 H HD12 . ILE A 1 305 ? 22.24139  -1.93429  -18.82960 1.000 24.86487  ? 297 ILE A HD12 1 
ATOM   4496 H HD13 . ILE A 1 305 ? 21.28157  -0.69206  -19.07275 1.000 24.86487  ? 297 ILE A HD13 1 
ATOM   4497 N N    . ASN A 1 306 ? 18.54858  -5.68344  -20.18016 1.000 14.21739  ? 298 ASN A N    1 
ATOM   4498 C CA   . ASN A 1 306 ? 17.88302  -6.26616  -21.33253 1.000 13.92733  ? 298 ASN A CA   1 
ATOM   4499 C C    . ASN A 1 306 ? 16.88911  -7.34717  -20.95417 1.000 15.06034  ? 298 ASN A C    1 
ATOM   4500 O O    . ASN A 1 306 ? 16.22163  -7.87772  -21.84784 1.000 17.20190  ? 298 ASN A O    1 
ATOM   4501 C CB   . ASN A 1 306 ? 18.91739  -6.83246  -22.30039 1.000 18.08304  ? 298 ASN A CB   1 
ATOM   4502 C CG   . ASN A 1 306 ? 19.77746  -5.75637  -22.91287 1.000 19.57557  ? 298 ASN A CG   1 
ATOM   4503 O OD1  . ASN A 1 306 ? 19.50830  -4.55979  -22.75063 1.000 20.32827  ? 298 ASN A OD1  1 
ATOM   4504 N ND2  . ASN A 1 306 ? 20.82269  -6.17279  -23.62993 1.000 27.44157  ? 298 ASN A ND2  1 
ATOM   4505 H H    . ASN A 1 306 ? 19.32443  -6.01571  -20.01503 1.000 17.07789  ? 298 ASN A H    1 
ATOM   4506 H HA   . ASN A 1 306 ? 17.39543  -5.56700  -21.79551 1.000 16.72981  ? 298 ASN A HA   1 
ATOM   4507 H HB2  . ASN A 1 306 ? 19.49678  -7.44658  -21.82282 1.000 21.71667  ? 298 ASN A HB2  1 
ATOM   4508 H HB3  . ASN A 1 306 ? 18.45988  -7.29804  -23.01789 1.000 21.71667  ? 298 ASN A HB3  1 
ATOM   4509 H HD21 . ASN A 1 306 ? 21.34546  -5.59949  -24.00093 1.000 32.94691  ? 298 ASN A HD21 1 
ATOM   4510 H HD22 . ASN A 1 306 ? 20.97367  -7.01451  -23.72113 1.000 32.94691  ? 298 ASN A HD22 1 
ATOM   4511 N N    . THR A 1 307 ? 16.73220  -7.64677  -19.66067 1.000 13.38700  ? 299 THR A N    1 
ATOM   4512 C CA   . THR A 1 307 ? 15.83059  -8.70222  -19.23058 1.000 15.71698  ? 299 THR A CA   1 
ATOM   4513 C C    . THR A 1 307 ? 14.78948  -8.25076  -18.22151 1.000 16.49433  ? 299 THR A C    1 
ATOM   4514 O O    . THR A 1 307 ? 14.02084  -9.09810  -17.75314 1.000 15.81082  ? 299 THR A O    1 
ATOM   4515 C CB   . THR A 1 307 ? 16.61984  -9.87827  -18.63609 1.000 17.89522  ? 299 THR A CB   1 
ATOM   4516 O OG1  . THR A 1 307 ? 17.34093  -9.44648  -17.47386 1.000 13.57113  ? 299 THR A OG1  1 
ATOM   4517 C CG2  . THR A 1 307 ? 17.58109  -10.43844 -19.66261 1.000 14.60964  ? 299 THR A CG2  1 
ATOM   4518 H H    . THR A 1 307 ? 17.14081  -7.24817  -19.01743 1.000 16.08142  ? 299 THR A H    1 
ATOM   4519 H HA   . THR A 1 307 ? 15.35872  -9.01984  -20.01630 1.000 18.87740  ? 299 THR A HA   1 
ATOM   4520 H HB   . THR A 1 307 ? 16.00668  -10.58399 -18.37745 1.000 21.49129  ? 299 THR A HB   1 
ATOM   4521 H HG1  . THR A 1 307 ? 18.02905  -9.02302  -17.70357 1.000 16.30238  ? 299 THR A HG1  1 
ATOM   4522 H HG21 . THR A 1 307 ? 18.06627  -11.18994 -19.28744 1.000 17.54860  ? 299 THR A HG21 1 
ATOM   4523 H HG22 . THR A 1 307 ? 17.09294  -10.73808 -20.44544 1.000 17.54860  ? 299 THR A HG22 1 
ATOM   4524 H HG23 . THR A 1 307 ? 18.21606  -9.75559  -19.92987 1.000 17.54860  ? 299 THR A HG23 1 
ATOM   4525 N N    . VAL A 1 308 ? 14.73042  -6.95780  -17.87408 1.000 16.32570  ? 300 VAL A N    1 
ATOM   4526 C CA   . VAL A 1 308 ? 13.71727  -6.44584  -16.95638 1.000 11.41087  ? 300 VAL A CA   1 
ATOM   4527 C C    . VAL A 1 308 ? 13.06192  -5.18890  -17.50907 1.000 12.74984  ? 300 VAL A C    1 
ATOM   4528 O O    . VAL A 1 308 ? 13.59762  -4.50983  -18.38911 1.000 16.80450  ? 300 VAL A O    1 
ATOM   4529 C CB   . VAL A 1 308 ? 14.31238  -6.14239  -15.56423 1.000 12.25644  ? 300 VAL A CB   1 
ATOM   4530 C CG1  . VAL A 1 308 ? 15.14929  -7.30891  -15.08111 1.000 20.66483  ? 300 VAL A CG1  1 
ATOM   4531 C CG2  . VAL A 1 308 ? 15.16721  -4.86606  -15.61364 1.000 19.31551  ? 300 VAL A CG2  1 
ATOM   4532 H H    . VAL A 1 308 ? 15.27372  -6.35674  -18.16243 1.000 19.60787  ? 300 VAL A H    1 
ATOM   4533 H HA   . VAL A 1 308 ? 13.02230  -7.11848  -16.88255 1.000 13.71007  ? 300 VAL A HA   1 
ATOM   4534 H HB   . VAL A 1 308 ? 13.58510  -6.00362  -14.93757 1.000 14.72475  ? 300 VAL A HB   1 
ATOM   4535 H HG11 . VAL A 1 308 ? 15.44447  -7.13164  -14.17428 1.000 24.81482  ? 300 VAL A HG11 1 
ATOM   4536 H HG12 . VAL A 1 308 ? 14.60967  -8.11469  -15.10177 1.000 24.81482  ? 300 VAL A HG12 1 
ATOM   4537 H HG13 . VAL A 1 308 ? 15.91715  -7.40997  -15.66512 1.000 24.81482  ? 300 VAL A HG13 1 
ATOM   4538 H HG21 . VAL A 1 308 ? 15.70174  -4.81251  -14.80598 1.000 23.19563  ? 300 VAL A HG21 1 
ATOM   4539 H HG22 . VAL A 1 308 ? 15.74575  -4.90335  -16.39133 1.000 23.19563  ? 300 VAL A HG22 1 
ATOM   4540 H HG23 . VAL A 1 308 ? 14.58106  -4.09554  -15.67407 1.000 23.19563  ? 300 VAL A HG23 1 
ATOM   4541 N N    . ASN A 1 309 ? 11.89389  -4.86106  -16.94689 1.000 12.89258  ? 301 ASN A N    1 
ATOM   4542 C CA   . ASN A 1 309 ? 11.30135  -3.53932  -17.11391 1.000 13.63046  ? 301 ASN A CA   1 
ATOM   4543 C C    . ASN A 1 309 ? 10.30621  -3.29468  -15.98073 1.000 14.07642  ? 301 ASN A C    1 
ATOM   4544 O O    . ASN A 1 309 ? 10.06833  -4.15776  -15.12942 1.000 15.18786  ? 301 ASN A O    1 
ATOM   4545 C CB   . ASN A 1 309 ? 10.65238  -3.37174  -18.50119 1.000 19.13037  ? 301 ASN A CB   1 
ATOM   4546 C CG   . ASN A 1 309 ? 9.61225   -4.43193  -18.81020 1.000 18.44374  ? 301 ASN A CG   1 
ATOM   4547 O OD1  . ASN A 1 309 ? 9.93679   -5.49042  -19.35057 1.000 23.53108  ? 301 ASN A OD1  1 
ATOM   4548 N ND2  . ASN A 1 309 ? 8.35251   -4.14695  -18.48724 1.000 18.46288  ? 301 ASN A ND2  1 
ATOM   4549 H H    . ASN A 1 309 ? 11.42523  -5.39406  -16.46124 1.000 15.48812  ? 301 ASN A H    1 
ATOM   4550 H HA   . ASN A 1 309 ? 12.00699  -2.87830  -17.03630 1.000 16.37357  ? 301 ASN A HA   1 
ATOM   4551 H HB2  . ASN A 1 309 ? 10.21599  -2.50636  -18.54107 1.000 22.97347  ? 301 ASN A HB2  1 
ATOM   4552 H HB3  . ASN A 1 309 ? 11.34347  -3.42637  -19.17965 1.000 22.97347  ? 301 ASN A HB3  1 
ATOM   4553 H HD21 . ASN A 1 309 ? 7.72876   -4.71795  -18.64376 1.000 22.17248  ? 301 ASN A HD21 1 
ATOM   4554 H HD22 . ASN A 1 309 ? 8.16251   -3.39185  -18.12209 1.000 22.17248  ? 301 ASN A HD22 1 
ATOM   4555 N N    . LEU A 1 310 ? 9.74210   -2.09208  -15.95752 1.000 12.13018  ? 302 LEU A N    1 
ATOM   4556 C CA   . LEU A 1 310 ? 8.70150   -1.77712  -14.99312 1.000 15.61796  ? 302 LEU A CA   1 
ATOM   4557 C C    . LEU A 1 310 ? 7.36730   -2.36561  -15.44019 1.000 19.50873  ? 302 LEU A C    1 
ATOM   4558 O O    . LEU A 1 310 ? 7.02559   -2.35777  -16.62585 1.000 16.52173  ? 302 LEU A O    1 
ATOM   4559 C CB   . LEU A 1 310 ? 8.56528   -0.26844  -14.82185 1.000 18.41665  ? 302 LEU A CB   1 
ATOM   4560 C CG   . LEU A 1 310 ? 9.79130   0.49049   -14.31852 1.000 12.94670  ? 302 LEU A CG   1 
ATOM   4561 C CD1  . LEU A 1 310 ? 9.43947   1.95940   -14.08166 1.000 18.54159  ? 302 LEU A CD1  1 
ATOM   4562 C CD2  . LEU A 1 310 ? 10.34034  -0.15161  -13.04047 1.000 13.14533  ? 302 LEU A CD2  1 
ATOM   4563 H H    . LEU A 1 310 ? 9.94472   -1.44605  -16.48780 1.000 14.57324  ? 302 LEU A H    1 
ATOM   4564 H HA   . LEU A 1 310 ? 8.93716   -2.15981  -14.13351 1.000 18.75858  ? 302 LEU A HA   1 
ATOM   4565 H HB2  . LEU A 1 310 ? 8.33436   0.10946   -15.68485 1.000 22.11700  ? 302 LEU A HB2  1 
ATOM   4566 H HB3  . LEU A 1 310 ? 7.85135   -0.10429  -14.18604 1.000 22.11700  ? 302 LEU A HB3  1 
ATOM   4567 H HG   . LEU A 1 310 ? 10.49001  0.44992   -14.99013 1.000 15.55306  ? 302 LEU A HG   1 
ATOM   4568 H HD11 . LEU A 1 310 ? 10.23277  2.42960   -13.78084 1.000 22.26693  ? 302 LEU A HD11 1 
ATOM   4569 H HD12 . LEU A 1 310 ? 9.12102   2.34579   -14.91244 1.000 22.26693  ? 302 LEU A HD12 1 
ATOM   4570 H HD13 . LEU A 1 310 ? 8.74662   2.01302   -13.40492 1.000 22.26693  ? 302 LEU A HD13 1 
ATOM   4571 H HD21 . LEU A 1 310 ? 11.06386  0.39600   -12.69760 1.000 15.79142  ? 302 LEU A HD21 1 
ATOM   4572 H HD22 . LEU A 1 310 ? 9.62828   -0.20766  -12.38417 1.000 15.79142  ? 302 LEU A HD22 1 
ATOM   4573 H HD23 . LEU A 1 310 ? 10.66842  -1.04024  -13.24930 1.000 15.79142  ? 302 LEU A HD23 1 
ATOM   4574 N N    . ASN A 1 311 ? 6.61360   -2.86539  -14.47963 1.000 15.50817  ? 303 ASN A N    1 
ATOM   4575 C CA   . ASN A 1 311 ? 5.28779   -3.41481  -14.73714 1.000 15.44743  ? 303 ASN A CA   1 
ATOM   4576 C C    . ASN A 1 311 ? 4.28303   -2.27999  -14.89434 1.000 14.82388  ? 303 ASN A C    1 
ATOM   4577 O O    . ASN A 1 311 ? 4.05165   -1.53580  -13.93573 1.000 18.66782  ? 303 ASN A O    1 
ATOM   4578 C CB   . ASN A 1 311 ? 4.89656   -4.31803  -13.57847 1.000 16.00516  ? 303 ASN A CB   1 
ATOM   4579 C CG   . ASN A 1 311 ? 3.63680   -5.13212  -13.84097 1.000 17.26861  ? 303 ASN A CG   1 
ATOM   4580 O OD1  . ASN A 1 311 ? 2.91926   -4.93081  -14.82383 1.000 16.18299  ? 303 ASN A OD1  1 
ATOM   4581 N ND2  . ASN A 1 311 ? 3.36154   -6.05455  -12.94001 1.000 19.15252  ? 303 ASN A ND2  1 
ATOM   4582 H H    . ASN A 1 311 ? 6.84664   -2.90121  -13.65258 1.000 18.62683  ? 303 ASN A H    1 
ATOM   4583 H HA   . ASN A 1 311 ? 5.28128   -3.93124  -15.55822 1.000 18.55393  ? 303 ASN A HA   1 
ATOM   4584 H HB2  . ASN A 1 311 ? 5.62126   -4.93970  -13.40749 1.000 19.22322  ? 303 ASN A HB2  1 
ATOM   4585 H HB3  . ASN A 1 311 ? 4.73755   -3.77000  -12.79407 1.000 19.22322  ? 303 ASN A HB3  1 
ATOM   4586 H HD21 . ASN A 1 311 ? 2.66349   -6.54875  -13.02999 1.000 23.00005  ? 303 ASN A HD21 1 
ATOM   4587 H HD22 . ASN A 1 311 ? 3.88005   -6.16202  -12.26237 1.000 23.00005  ? 303 ASN A HD22 1 
ATOM   4588 N N    . PRO A 1 312 ? 3.67282   -2.10262  -16.07275 1.000 15.46094  ? 304 PRO A N    1 
ATOM   4589 C CA   . PRO A 1 312 ? 2.65235   -1.04843  -16.20272 1.000 17.26146  ? 304 PRO A CA   1 
ATOM   4590 C C    . PRO A 1 312 ? 1.39059   -1.31431  -15.39934 1.000 14.98639  ? 304 PRO A C    1 
ATOM   4591 O O    . PRO A 1 312 ? 0.60184   -0.38013  -15.20996 1.000 19.83410  ? 304 PRO A O    1 
ATOM   4592 C CB   . PRO A 1 312 ? 2.35581   -1.01449  -17.70903 1.000 22.44024  ? 304 PRO A CB   1 
ATOM   4593 C CG   . PRO A 1 312 ? 2.75298   -2.36140  -18.21515 1.000 22.24903  ? 304 PRO A CG   1 
ATOM   4594 C CD   . PRO A 1 312 ? 3.87063   -2.86448  -17.32220 1.000 17.59147  ? 304 PRO A CD   1 
ATOM   4595 H HA   . PRO A 1 312 ? 3.02635   -0.19346  -15.93805 1.000 20.73077  ? 304 PRO A HA   1 
ATOM   4596 H HB2  . PRO A 1 312 ? 1.41039   -0.85421  -17.85525 1.000 26.94531  ? 304 PRO A HB2  1 
ATOM   4597 H HB3  . PRO A 1 312 ? 2.87997   -0.31672  -18.13244 1.000 26.94531  ? 304 PRO A HB3  1 
ATOM   4598 H HG2  . PRO A 1 312 ? 1.99013   -2.95898  -18.17195 1.000 26.71586  ? 304 PRO A HG2  1 
ATOM   4599 H HG3  . PRO A 1 312 ? 3.06121   -2.28260  -19.13149 1.000 26.71586  ? 304 PRO A HG3  1 
ATOM   4600 H HD2  . PRO A 1 312 ? 3.78368   -3.81743  -17.16336 1.000 21.12679  ? 304 PRO A HD2  1 
ATOM   4601 H HD3  . PRO A 1 312 ? 4.73772   -2.67079  -17.71148 1.000 21.12679  ? 304 PRO A HD3  1 
ATOM   4602 N N    . ALA A 1 313 ? 1.18923   -2.52612  -14.88254 1.000 20.91829  ? 305 ALA A N    1 
ATOM   4603 C CA   . ALA A 1 313 ? -0.00909  -2.86379  -14.11070 1.000 24.05913  ? 305 ALA A CA   1 
ATOM   4604 C C    . ALA A 1 313 ? 0.37270   -3.73701  -12.92517 1.000 17.71411  ? 305 ALA A C    1 
ATOM   4605 O O    . ALA A 1 313 ? -0.00625  -4.90838  -12.84398 1.000 18.00614  ? 305 ALA A O    1 
ATOM   4606 C CB   . ALA A 1 313 ? -1.04502  -3.56929  -14.99263 1.000 25.78908  ? 305 ALA A CB   1 
ATOM   4607 H H    . ALA A 1 313 ? 1.74090   -3.18051  -14.96648 1.000 25.11897  ? 305 ALA A H    1 
ATOM   4608 H HA   . ALA A 1 313 ? -0.39365  -2.04214  -13.76731 1.000 28.88798  ? 305 ALA A HA   1 
ATOM   4609 H HB1  . ALA A 1 313 ? -1.82686  -3.77657  -14.45723 1.000 30.96392  ? 305 ALA A HB1  1 
ATOM   4610 H HB2  . ALA A 1 313 ? -1.29105  -2.98064  -15.72329 1.000 30.96392  ? 305 ALA A HB2  1 
ATOM   4611 H HB3  . ALA A 1 313 ? -0.65755  -4.38679  -15.34258 1.000 30.96392  ? 305 ALA A HB3  1 
ATOM   4612 N N    . PRO A 1 314 ? 1.12914   -3.19387  -11.97670 1.000 16.75363  ? 306 PRO A N    1 
ATOM   4613 C CA   . PRO A 1 314 ? 1.43803   -3.95432  -10.76359 1.000 17.36967  ? 306 PRO A CA   1 
ATOM   4614 C C    . PRO A 1 314 ? 0.19970   -4.08779  -9.89009  1.000 21.83939  ? 306 PRO A C    1 
ATOM   4615 O O    . PRO A 1 314 ? -0.82936  -3.44834  -10.10888 1.000 21.38161  ? 306 PRO A O    1 
ATOM   4616 C CB   . PRO A 1 314 ? 2.52977   -3.12831  -10.08060 1.000 18.23437  ? 306 PRO A CB   1 
ATOM   4617 C CG   . PRO A 1 314 ? 2.32709   -1.73555  -10.57170 1.000 18.80185  ? 306 PRO A CG   1 
ATOM   4618 C CD   . PRO A 1 314 ? 1.66662   -1.82345  -11.94403 1.000 17.74210  ? 306 PRO A CD   1 
ATOM   4619 H HA   . PRO A 1 314 ? 1.79340   -4.83144  -10.97637 1.000 20.86063  ? 306 PRO A HA   1 
ATOM   4620 H HB2  . PRO A 1 314 ? 2.42478   -3.17514  -9.11744  1.000 21.89826  ? 306 PRO A HB2  1 
ATOM   4621 H HB3  . PRO A 1 314 ? 3.40406   -3.46218  -10.33564 1.000 21.89826  ? 306 PRO A HB3  1 
ATOM   4622 H HG2  . PRO A 1 314 ? 1.75434   -1.25755  -9.95171  1.000 22.57925  ? 306 PRO A HG2  1 
ATOM   4623 H HG3  . PRO A 1 314 ? 3.18681   -1.29141  -10.63895 1.000 22.57925  ? 306 PRO A HG3  1 
ATOM   4624 H HD2  . PRO A 1 314 ? 0.95332   -1.17122  -12.02587 1.000 21.30754  ? 306 PRO A HD2  1 
ATOM   4625 H HD3  . PRO A 1 314 ? 2.31897   -1.69196  -12.64976 1.000 21.30754  ? 306 PRO A HD3  1 
ATOM   4626 N N    . ILE A 1 315 ? 0.30613   -4.95416  -8.88973  1.000 20.34564  ? 307 ILE A N    1 
ATOM   4627 C CA   . ILE A 1 315 ? -0.78757  -5.12624  -7.93901  1.000 23.57929  ? 307 ILE A CA   1 
ATOM   4628 C C    . ILE A 1 315 ? -0.92197  -3.85289  -7.11455  1.000 29.08192  ? 307 ILE A C    1 
ATOM   4629 O O    . ILE A 1 315 ? 0.02802   -3.42488  -6.44713  1.000 23.38860  ? 307 ILE A O    1 
ATOM   4630 C CB   . ILE A 1 315 ? -0.55192  -6.34725  -7.04257  1.000 23.84294  ? 307 ILE A CB   1 
ATOM   4631 C CG1  . ILE A 1 315 ? -0.48017  -7.62100  -7.88283  1.000 27.63214  ? 307 ILE A CG1  1 
ATOM   4632 C CG2  . ILE A 1 315 ? -1.66521  -6.45581  -5.99401  1.000 25.04178  ? 307 ILE A CG2  1 
ATOM   4633 C CD1  . ILE A 1 315 ? 0.24921   -8.75696  -7.19954  1.000 29.59792  ? 307 ILE A CD1  1 
ATOM   4634 H H    . ILE A 1 315 ? 0.99301   -5.44953  -8.74004  1.000 24.43179  ? 307 ILE A H    1 
ATOM   4635 H HA   . ILE A 1 315 ? -1.61425  -5.26603  -8.42683  1.000 28.31217  ? 307 ILE A HA   1 
ATOM   4636 H HB   . ILE A 1 315 ? 0.29645   -6.23514  -6.58583  1.000 28.62855  ? 307 ILE A HB   1 
ATOM   4637 H HG12 . ILE A 1 315 ? -1.38275  -7.92039  -8.07420  1.000 33.17559  ? 307 ILE A HG12 1 
ATOM   4638 H HG13 . ILE A 1 315 ? -0.01364  -7.42380  -8.71008  1.000 33.17559  ? 307 ILE A HG13 1 
ATOM   4639 H HG21 . ILE A 1 315 ? -1.59196  -7.31148  -5.54306  1.000 30.06716  ? 307 ILE A HG21 1 
ATOM   4640 H HG22 . ILE A 1 315 ? -1.56665  -5.73455  -5.35294  1.000 30.06716  ? 307 ILE A HG22 1 
ATOM   4641 H HG23 . ILE A 1 315 ? -2.52495  -6.38847  -6.43810  1.000 30.06716  ? 307 ILE A HG23 1 
ATOM   4642 H HD11 . ILE A 1 315 ? 0.28134   -9.51812  -7.79996  1.000 35.53453  ? 307 ILE A HD11 1 
ATOM   4643 H HD12 . ILE A 1 315 ? 1.14957   -8.46880  -6.98227  1.000 35.53453  ? 307 ILE A HD12 1 
ATOM   4644 H HD13 . ILE A 1 315 ? -0.22659  -8.99527  -6.38853  1.000 35.53453  ? 307 ILE A HD13 1 
ATOM   4645 N N    . LYS A 1 316 ? -2.09640  -3.22156  -7.18733  1.000 31.71608  ? 308 LYS A N    1 
ATOM   4646 C CA   . LYS A 1 316 ? -2.40839  -2.04172  -6.39068  1.000 30.56773  ? 308 LYS A CA   1 
ATOM   4647 C C    . LYS A 1 316 ? -2.95310  -2.42542  -5.02242  1.000 34.92119  ? 308 LYS A C    1 
ATOM   4648 O O    . LYS A 1 316 ? -2.67908  -1.74541  -4.02999  1.000 34.08052  ? 308 LYS A O    1 
ATOM   4649 C CB   . LYS A 1 316 ? -3.42876  -1.16529  -7.12591  1.000 33.71982  ? 308 LYS A CB   1 
ATOM   4650 C CG   . LYS A 1 316 ? -3.79337  0.13182   -6.41183  1.000 53.01266  ? 308 LYS A CG   1 
ATOM   4651 C CD   . LYS A 1 316 ? -5.14936  0.66037   -6.89101  1.000 70.95987  ? 308 LYS A CD   1 
ATOM   4652 C CE   . LYS A 1 316 ? -5.31080  2.15056   -6.61136  1.000 72.70521  ? 308 LYS A CE   1 
ATOM   4653 N NZ   . LYS A 1 316 ? -5.68771  2.91033   -7.84090  1.000 71.21977  ? 308 LYS A NZ   1 
ATOM   4654 H H    . LYS A 1 316 ? -2.74049  -3.46493  -7.70261  1.000 38.07632  ? 308 LYS A H    1 
ATOM   4655 H HA   . LYS A 1 316 ? -1.60266  -1.51593  -6.26727  1.000 36.69830  ? 308 LYS A HA   1 
ATOM   4656 H HB2  . LYS A 1 316 ? -3.06247  -0.92789  -7.99216  1.000 40.48081  ? 308 LYS A HB2  1 
ATOM   4657 H HB3  . LYS A 1 316 ? -4.24624  -1.67486  -7.23974  1.000 40.48081  ? 308 LYS A HB3  1 
ATOM   4658 H HG2  . LYS A 1 316 ? -3.84680  -0.02907  -5.45676  1.000 63.63222  ? 308 LYS A HG2  1 
ATOM   4659 H HG3  . LYS A 1 316 ? -3.11894  0.80372   -6.59786  1.000 63.63222  ? 308 LYS A HG3  1 
ATOM   4660 H HD2  . LYS A 1 316 ? -5.22654  0.52152   -7.84791  1.000 85.16887  ? 308 LYS A HD2  1 
ATOM   4661 H HD3  . LYS A 1 316 ? -5.85853  0.18674   -6.42878  1.000 85.16887  ? 308 LYS A HD3  1 
ATOM   4662 H HE2  . LYS A 1 316 ? -6.00897  2.27788   -5.95011  1.000 87.26327  ? 308 LYS A HE2  1 
ATOM   4663 H HE3  . LYS A 1 316 ? -4.47137  2.50641   -6.28024  1.000 87.26327  ? 308 LYS A HE3  1 
ATOM   4664 H HZ1  . LYS A 1 316 ? -5.76523  3.77652   -7.65168  1.000 85.48075  ? 308 LYS A HZ1  1 
ATOM   4665 H HZ2  . LYS A 1 316 ? -5.06333  2.80610   -8.46650  1.000 85.48075  ? 308 LYS A HZ2  1 
ATOM   4666 H HZ3  . LYS A 1 316 ? -6.46501  2.61287   -8.15622  1.000 85.48075  ? 308 LYS A HZ3  1 
ATOM   4667 N N    . ASN A 1 317 ? -3.71274  -3.51307  -4.95731  1.000 30.62591  ? 309 ASN A N    1 
ATOM   4668 C CA   . ASN A 1 317 ? -4.41063  -3.94212  -3.74810  1.000 51.72448  ? 309 ASN A CA   1 
ATOM   4669 C C    . ASN A 1 317 ? -3.93811  -5.35771  -3.43571  1.000 22.53451  ? 309 ASN A C    1 
ATOM   4670 O O    . ASN A 1 317 ? -4.44404  -6.33060  -4.00377  1.000 39.41493  ? 309 ASN A O    1 
ATOM   4671 C CB   . ASN A 1 317 ? -5.92450  -3.87638  -3.94315  1.000 69.67761  ? 309 ASN A CB   1 
ATOM   4672 C CG   . ASN A 1 317 ? -6.69265  -4.21515  -2.68192  1.000 67.55571  ? 309 ASN A CG   1 
ATOM   4673 O OD1  . ASN A 1 317 ? -6.23037  -4.99618  -1.84894  1.000 49.93822  ? 309 ASN A OD1  1 
ATOM   4674 N ND2  . ASN A 1 317 ? -7.87711  -3.63058  -2.53742  1.000 68.04363  ? 309 ASN A ND2  1 
ATOM   4675 H H    . ASN A 1 317 ? -3.84458  -4.03871  -5.62508  1.000 36.76812  ? 309 ASN A H    1 
ATOM   4676 H HA   . ASN A 1 317 ? -4.17860  -3.36539  -3.00350  1.000 62.08640  ? 309 ASN A HA   1 
ATOM   4677 H HB2  . ASN A 1 317 ? -6.16996  -2.97714  -4.21153  1.000 83.63015  ? 309 ASN A HB2  1 
ATOM   4678 H HB3  . ASN A 1 317 ? -6.18249  -4.50992  -4.63088  1.000 83.63015  ? 309 ASN A HB3  1 
ATOM   4679 H HD21 . ASN A 1 317 ? -8.16805  -3.09313  -3.14249  1.000 81.66938  ? 309 ASN A HD21 1 
ATOM   4680 H HD22 . ASN A 1 317 ? -8.35279  -3.78968  -1.83884  1.000 81.66938  ? 309 ASN A HD22 1 
ATOM   4681 N N    . LEU A 1 318 ? -2.95879  -5.47435  -2.53771  1.000 32.10372  ? 310 LEU A N    1 
ATOM   4682 C CA   . LEU A 1 318 ? -2.39966  -6.78245  -2.22292  1.000 26.88715  ? 310 LEU A CA   1 
ATOM   4683 C C    . LEU A 1 318 ? -3.39520  -7.67360  -1.49971  1.000 41.66212  ? 310 LEU A C    1 
ATOM   4684 O O    . LEU A 1 318 ? -3.13335  -8.87190  -1.35297  1.000 31.34788  ? 310 LEU A O    1 
ATOM   4685 C CB   . LEU A 1 318 ? -1.12682  -6.62234  -1.38733  1.000 33.37750  ? 310 LEU A CB   1 
ATOM   4686 C CG   . LEU A 1 318 ? 0.04452   -6.00776  -2.15541  1.000 26.98183  ? 310 LEU A CG   1 
ATOM   4687 C CD1  . LEU A 1 318 ? 1.13046   -5.49263  -1.22106  1.000 35.65134  ? 310 LEU A CD1  1 
ATOM   4688 C CD2  . LEU A 1 318 ? 0.62386   -7.00858  -3.13975  1.000 27.91252  ? 310 LEU A CD2  1 
ATOM   4689 H H    . LEU A 1 318 ? -2.60789  -4.81928  -2.10485  1.000 38.54149  ? 310 LEU A H    1 
ATOM   4690 H HA   . LEU A 1 318 ? -2.14880  -7.22712  -3.04769  1.000 32.28161  ? 310 LEU A HA   1 
ATOM   4691 H HB2  . LEU A 1 318 ? -1.32134  -6.04539  -0.63223  1.000 40.07003  ? 310 LEU A HB2  1 
ATOM   4692 H HB3  . LEU A 1 318 ? -0.84902  -7.49713  -1.07354  1.000 40.07003  ? 310 LEU A HB3  1 
ATOM   4693 H HG   . LEU A 1 318 ? -0.29255  -5.24542  -2.65152  1.000 32.39522  ? 310 LEU A HG   1 
ATOM   4694 H HD11 . LEU A 1 318 ? 1.83388   -5.08397  -1.74936  1.000 42.79863  ? 310 LEU A HD11 1 
ATOM   4695 H HD12 . LEU A 1 318 ? 0.74463   -4.83645  -0.61985  1.000 42.79863  ? 310 LEU A HD12 1 
ATOM   4696 H HD13 . LEU A 1 318 ? 1.48868   -6.23692  -0.71251  1.000 42.79863  ? 310 LEU A HD13 1 
ATOM   4697 H HD21 . LEU A 1 318 ? 1.37571   -6.60174  -3.59810  1.000 33.51205  ? 310 LEU A HD21 1 
ATOM   4698 H HD22 . LEU A 1 318 ? 0.91862   -7.79480  -2.65408  1.000 33.51205  ? 310 LEU A HD22 1 
ATOM   4699 H HD23 . LEU A 1 318 ? -0.06134  -7.25358  -3.78114  1.000 33.51205  ? 310 LEU A HD23 1 
ATOM   4700 N N    . ILE A 1 319 ? -4.52771  -7.12280  -1.06364  1.000 45.14175  ? 311 ILE A N    1 
ATOM   4701 C CA   . ILE A 1 319 ? -5.58994  -7.94207  -0.49390  1.000 47.63480  ? 311 ILE A CA   1 
ATOM   4702 C C    . ILE A 1 319 ? -6.41776  -8.58079  -1.60054  1.000 49.15336  ? 311 ILE A C    1 
ATOM   4703 O O    . ILE A 1 319 ? -6.65819  -9.79402  -1.60006  1.000 42.77287  ? 311 ILE A O    1 
ATOM   4704 C CB   . ILE A 1 319 ? -6.46685  -7.09255  0.44579   1.000 64.99726  ? 311 ILE A CB   1 
ATOM   4705 C CG1  . ILE A 1 319 ? -5.82127  -6.97139  1.82861   1.000 45.42257  ? 311 ILE A CG1  1 
ATOM   4706 C CG2  . ILE A 1 319 ? -7.86456  -7.69701  0.57277   1.000 57.76481  ? 311 ILE A CG2  1 
ATOM   4707 C CD1  . ILE A 1 319 ? -4.43113  -6.36873  1.81255   1.000 53.38926  ? 311 ILE A CD1  1 
ATOM   4708 H H    . ILE A 1 319 ? -4.70325  -6.28123  -1.08702  1.000 54.18712  ? 311 ILE A H    1 
ATOM   4709 H HA   . ILE A 1 319 ? -5.18890  -8.65296  0.03021   1.000 57.17878  ? 311 ILE A HA   1 
ATOM   4710 H HB   . ILE A 1 319 ? -6.54223  -6.20610  0.05925   1.000 78.01373  ? 311 ILE A HB   1 
ATOM   4711 H HG12 . ILE A 1 319 ? -6.38081  -6.40627  2.38400   1.000 54.52411  ? 311 ILE A HG12 1 
ATOM   4712 H HG13 . ILE A 1 319 ? -5.75377  -7.85707  2.21838   1.000 54.52411  ? 311 ILE A HG13 1 
ATOM   4713 H HG21 . ILE A 1 319 ? -8.31963  -7.28528  1.32397   1.000 69.33480  ? 311 ILE A HG21 1 
ATOM   4714 H HG22 . ILE A 1 319 ? -8.35727  -7.52795  -0.24549  1.000 69.33480  ? 311 ILE A HG22 1 
ATOM   4715 H HG23 . ILE A 1 319 ? -7.78334  -8.65254  0.71856   1.000 69.33480  ? 311 ILE A HG23 1 
ATOM   4716 H HD11 . ILE A 1 319 ? -4.17075  -6.15111  2.72125   1.000 64.08414  ? 311 ILE A HD11 1 
ATOM   4717 H HD12 . ILE A 1 319 ? -3.81172  -7.01352  1.43639   1.000 64.08414  ? 311 ILE A HD12 1 
ATOM   4718 H HD13 . ILE A 1 319 ? -4.44172  -5.56475  1.26995   1.000 64.08414  ? 311 ILE A HD13 1 
ATOM   4719 N N    . THR A 1 320 ? -6.86053  -7.77247  -2.56566  1.000 40.96823  ? 312 THR A N    1 
ATOM   4720 C CA   . THR A 1 320 ? -7.71471  -8.28323  -3.63162  1.000 30.10520  ? 312 THR A CA   1 
ATOM   4721 C C    . THR A 1 320 ? -6.91675  -8.90404  -4.76877  1.000 48.29286  ? 312 THR A C    1 
ATOM   4722 O O    . THR A 1 320 ? -7.37157  -9.87812  -5.38166  1.000 55.92438  ? 312 THR A O    1 
ATOM   4723 C CB   . THR A 1 320 ? -8.58736  -7.16103  -4.20352  1.000 43.71137  ? 312 THR A CB   1 
ATOM   4724 O OG1  . THR A 1 320 ? -7.75934  -6.19735  -4.86794  1.000 53.05244  ? 312 THR A OG1  1 
ATOM   4725 C CG2  . THR A 1 320 ? -9.37712  -6.46908  -3.10532  1.000 62.55762  ? 312 THR A CG2  1 
ATOM   4726 H H    . THR A 1 320 ? -6.68141  -6.93333  -2.62359  1.000 49.17889  ? 312 THR A H    1 
ATOM   4727 H HA   . THR A 1 320 ? -8.29013  -8.96274  -3.24684  1.000 36.14326  ? 312 THR A HA   1 
ATOM   4728 H HB   . THR A 1 320 ? -9.21793  -7.54133  -4.83491  1.000 52.47067  ? 312 THR A HB   1 
ATOM   4729 H HG1  . THR A 1 320 ? -8.22385  -5.54427  -5.11957  1.000 63.67995  ? 312 THR A HG1  1 
ATOM   4730 H HG21 . THR A 1 320 ? -9.83631  -5.69400  -3.46490  1.000 75.08617  ? 312 THR A HG21 1 
ATOM   4731 H HG22 . THR A 1 320 ? -10.03316 -7.07928  -2.73363  1.000 75.08617  ? 312 THR A HG22 1 
ATOM   4732 H HG23 . THR A 1 320 ? -8.77920  -6.18068  -2.39805  1.000 75.08617  ? 312 THR A HG23 1 
ATOM   4733 N N    . GLY A 1 321 ? -5.73910  -8.36282  -5.06304  1.000 38.72160  ? 313 GLY A N    1 
ATOM   4734 C CA   . GLY A 1 321 ? -5.05503  -8.66955  -6.29527  1.000 39.89469  ? 313 GLY A CA   1 
ATOM   4735 C C    . GLY A 1 321 ? -5.36606  -7.70275  -7.40886  1.000 38.94936  ? 313 GLY A C    1 
ATOM   4736 O O    . GLY A 1 321 ? -4.85727  -7.88054  -8.52354  1.000 39.59680  ? 313 GLY A O    1 
ATOM   4737 H H    . GLY A 1 321 ? -5.31849  -7.81078  -4.55517  1.000 46.48295  ? 313 GLY A H    1 
ATOM   4738 H HA2  . GLY A 1 321 ? -4.09793  -8.65222  -6.13855  1.000 47.89065  ? 313 GLY A HA2  1 
ATOM   4739 H HA3  . GLY A 1 321 ? -5.31130  -9.55859  -6.58653  1.000 47.89065  ? 313 GLY A HA3  1 
ATOM   4740 N N    . GLU A 1 322 ? -6.19434  -6.69435  -7.14096  1.000 35.09394  ? 314 GLU A N    1 
ATOM   4741 C CA   . GLU A 1 322 ? -6.52259  -5.68634  -8.13829  1.000 49.62851  ? 314 GLU A CA   1 
ATOM   4742 C C    . GLU A 1 322 ? -5.26424  -4.95050  -8.57108  1.000 32.72144  ? 314 GLU A C    1 
ATOM   4743 O O    . GLU A 1 322 ? -4.46026  -4.52914  -7.73544  1.000 32.13276  ? 314 GLU A O    1 
ATOM   4744 C CB   . GLU A 1 322 ? -7.54139  -4.69606  -7.56774  1.000 38.88885  ? 314 GLU A CB   1 
ATOM   4745 C CG   . GLU A 1 322 ? -7.98352  -3.61705  -8.54198  1.000 57.38791  ? 314 GLU A CG   1 
ATOM   4746 C CD   . GLU A 1 322 ? -8.28140  -2.28539  -7.85743  1.000 84.76237  ? 314 GLU A CD   1 
ATOM   4747 O OE1  . GLU A 1 322 ? -8.83613  -1.38253  -8.52188  1.000 76.59144  ? 314 GLU A OE1  1 
ATOM   4748 O OE2  . GLU A 1 322 ? -7.95833  -2.13495  -6.65845  1.000 79.67515  ? 314 GLU A OE2  1 
ATOM   4749 H H    . GLU A 1 322 ? -6.58125  -6.57236  -6.38265  1.000 42.12975  ? 314 GLU A H    1 
ATOM   4750 H HA   . GLU A 1 322 ? -6.91527  -6.11434  -8.91516  1.000 59.57123  ? 314 GLU A HA   1 
ATOM   4751 H HB2  . GLU A 1 322 ? -8.33216  -5.18801  -7.29650  1.000 46.68365  ? 314 GLU A HB2  1 
ATOM   4752 H HB3  . GLU A 1 322 ? -7.14621  -4.25389  -6.80013  1.000 46.68365  ? 314 GLU A HB3  1 
ATOM   4753 H HG2  . GLU A 1 322 ? -7.27767  -3.46900  -9.19065  1.000 68.88252  ? 314 GLU A HG2  1 
ATOM   4754 H HG3  . GLU A 1 322 ? -8.79147  -3.90981  -8.99187  1.000 68.88252  ? 314 GLU A HG3  1 
ATOM   4755 N N    . ARG A 1 323 ? -5.10764  -4.78183  -9.87883  1.000 32.84162  ? 315 ARG A N    1 
ATOM   4756 C CA   . ARG A 1 323 ? -3.93850  -4.13432  -10.44845 1.000 28.94975  ? 315 ARG A CA   1 
ATOM   4757 C C    . ARG A 1 323 ? -4.26172  -2.70231  -10.85398 1.000 38.46112  ? 315 ARG A C    1 
ATOM   4758 O O    . ARG A 1 323 ? -5.41289  -2.35510  -11.13324 1.000 35.74273  ? 315 ARG A O    1 
ATOM   4759 C CB   . ARG A 1 323 ? -3.42687  -4.92224  -11.65564 1.000 24.37078  ? 315 ARG A CB   1 
ATOM   4760 C CG   . ARG A 1 323 ? -3.10958  -6.36540  -11.33744 1.000 22.50668  ? 315 ARG A CG   1 
ATOM   4761 C CD   . ARG A 1 323 ? -2.56874  -7.11809  -12.54753 1.000 32.32239  ? 315 ARG A CD   1 
ATOM   4762 N NE   . ARG A 1 323 ? -1.97116  -8.38788  -12.14935 1.000 30.07644  ? 315 ARG A NE   1 
ATOM   4763 C CZ   . ARG A 1 323 ? -0.73060  -8.51807  -11.68874 1.000 39.08925  ? 315 ARG A CZ   1 
ATOM   4764 N NH1  . ARG A 1 323 ? 0.05539   -7.45024  -11.57810 1.000 21.71512  ? 315 ARG A NH1  1 
ATOM   4765 N NH2  . ARG A 1 323 ? -0.27422  -9.71719  -11.34583 1.000 32.14495  ? 315 ARG A NH2  1 
ATOM   4766 H H    . ARG A 1 323 ? -5.67891  -5.04053  -10.46732 1.000 39.42697  ? 315 ARG A H    1 
ATOM   4767 H HA   . ARG A 1 323 ? -3.23163  -4.09913  -9.78512  1.000 34.75673  ? 315 ARG A HA   1 
ATOM   4768 H HB2  . ARG A 1 323 ? -4.10662  -4.91213  -12.34755 1.000 29.26195  ? 315 ARG A HB2  1 
ATOM   4769 H HB3  . ARG A 1 323 ? -2.61501  -4.50360  -11.98202 1.000 29.26195  ? 315 ARG A HB3  1 
ATOM   4770 H HG2  . ARG A 1 323 ? -2.43842  -6.39706  -10.63784 1.000 27.02504  ? 315 ARG A HG2  1 
ATOM   4771 H HG3  . ARG A 1 323 ? -3.91851  -6.81149  -11.04158 1.000 27.02504  ? 315 ARG A HG3  1 
ATOM   4772 H HD2  . ARG A 1 323 ? -3.29411  -7.30031  -13.16521 1.000 38.80389  ? 315 ARG A HD2  1 
ATOM   4773 H HD3  . ARG A 1 323 ? -1.88831  -6.58183  -12.98380 1.000 38.80389  ? 315 ARG A HD3  1 
ATOM   4774 H HE   . ARG A 1 323 ? -2.45198  -9.09771  -12.21683 1.000 36.10875  ? 315 ARG A HE   1 
ATOM   4775 H HH11 . ARG A 1 323 ? -0.23873  -6.67449  -11.80463 1.000 26.07517  ? 315 ARG A HH11 1 
ATOM   4776 H HH12 . ARG A 1 323 ? 0.85754   -7.53577  -11.28005 1.000 26.07517  ? 315 ARG A HH12 1 
ATOM   4777 H HH21 . ARG A 1 323 ? -0.78081  -10.40797 -11.42184 1.000 38.59096  ? 315 ARG A HH21 1 
ATOM   4778 H HH22 . ARG A 1 323 ? 0.52792   -9.80290  -11.04777 1.000 38.59096  ? 315 ARG A HH22 1 
ATOM   4779 N N    . TYR A 1 324 ? -3.23154  -1.85997  -10.84606 1.000 23.47829  ? 316 TYR A N    1 
ATOM   4780 C CA   . TYR A 1 324 ? -3.35483  -0.53347  -11.43308 1.000 30.85347  ? 316 TYR A CA   1 
ATOM   4781 C C    . TYR A 1 324 ? -3.95527  -0.63462  -12.83139 1.000 35.27545  ? 316 TYR A C    1 
ATOM   4782 O O    . TYR A 1 324 ? -3.59125  -1.51205  -13.61604 1.000 31.79139  ? 316 TYR A O    1 
ATOM   4783 C CB   . TYR A 1 324 ? -1.98473  0.14318   -11.51816 1.000 27.31594  ? 316 TYR A CB   1 
ATOM   4784 C CG   . TYR A 1 324 ? -1.43936  0.63661   -10.20310 1.000 22.87228  ? 316 TYR A CG   1 
ATOM   4785 C CD1  . TYR A 1 324 ? -1.52520  1.97193   -9.85500  1.000 27.76193  ? 316 TYR A CD1  1 
ATOM   4786 C CD2  . TYR A 1 324 ? -0.82309  -0.23116  -9.31842  1.000 24.85260  ? 316 TYR A CD2  1 
ATOM   4787 C CE1  . TYR A 1 324 ? -1.02461  2.43035   -8.65505  1.000 31.35805  ? 316 TYR A CE1  1 
ATOM   4788 C CE2  . TYR A 1 324 ? -0.31907  0.21690   -8.11814  1.000 23.14355  ? 316 TYR A CE2  1 
ATOM   4789 C CZ   . TYR A 1 324 ? -0.41516  1.54745   -7.79325  1.000 23.11135  ? 316 TYR A CZ   1 
ATOM   4790 O OH   . TYR A 1 324 ? 0.08702   2.00577   -6.59587  1.000 29.41097  ? 316 TYR A OH   1 
ATOM   4791 H H    . TYR A 1 324 ? -2.45889  -2.03219  -10.50999 1.000 28.19098  ? 316 TYR A H    1 
ATOM   4792 H HA   . TYR A 1 324 ? -3.93091  0.01085   -10.87385 1.000 37.04118  ? 316 TYR A HA   1 
ATOM   4793 H HB2  . TYR A 1 324 ? -1.34820  -0.49502  -11.87653 1.000 32.79615  ? 316 TYR A HB2  1 
ATOM   4794 H HB3  . TYR A 1 324 ? -2.05589  0.90862   -12.10971 1.000 32.79615  ? 316 TYR A HB3  1 
ATOM   4795 H HD1  . TYR A 1 324 ? -1.92785  2.57161   -10.44080 1.000 33.33133  ? 316 TYR A HD1  1 
ATOM   4796 H HD2  . TYR A 1 324 ? -0.74822  -1.13167  -9.53834  1.000 29.84015  ? 316 TYR A HD2  1 
ATOM   4797 H HE1  . TYR A 1 324 ? -1.09825  3.32962   -8.42968  1.000 37.64668  ? 316 TYR A HE1  1 
ATOM   4798 H HE2  . TYR A 1 324 ? 0.08489   -0.37934  -7.52973  1.000 27.78928  ? 316 TYR A HE2  1 
ATOM   4799 H HH   . TYR A 1 324 ? -0.07515  2.82561   -6.51128  1.000 35.31019  ? 316 TYR A HH   1 
ATOM   4800 N N    . THR A 1 325 ? -4.87454  0.27503   -13.14973 1.000 48.73123  ? 317 THR A N    1 
ATOM   4801 C CA   . THR A 1 325 ? -5.39732  0.36249   -14.50883 1.000 44.43789  ? 317 THR A CA   1 
ATOM   4802 C C    . THR A 1 325 ? -4.54806  1.26340   -15.39529 1.000 40.87372  ? 317 THR A C    1 
ATOM   4803 O O    . THR A 1 325 ? -4.60631  1.13743   -16.62423 1.000 40.65257  ? 317 THR A O    1 
ATOM   4804 C CB   . THR A 1 325 ? -6.84715  0.86258   -14.49056 1.000 39.40363  ? 317 THR A CB   1 
ATOM   4805 O OG1  . THR A 1 325 ? -6.88381  2.22088   -14.04282 1.000 60.03431  ? 317 THR A OG1  1 
ATOM   4806 C CG2  . THR A 1 325 ? -7.69690  -0.00471  -13.56749 1.000 47.73310  ? 317 THR A CG2  1 
ATOM   4807 H H    . THR A 1 325 ? -5.20769  0.84709   -12.60077 1.000 58.49450  ? 317 THR A H    1 
ATOM   4808 H HA   . THR A 1 325 ? -5.40848  -0.52229  -14.90626 1.000 53.34249  ? 317 THR A HA   1 
ATOM   4809 H HB   . THR A 1 325 ? -7.21973  0.81252   -15.38475 1.000 47.30138  ? 317 THR A HB   1 
ATOM   4810 H HG1  . THR A 1 325 ? -7.67531  2.50217   -14.04297 1.000 72.05819  ? 317 THR A HG1  1 
ATOM   4811 H HG21 . THR A 1 325 ? -8.61518  0.30778   -13.57105 1.000 57.29674  ? 317 THR A HG21 1 
ATOM   4812 H HG22 . THR A 1 325 ? -7.67703  -0.92693  -13.86752 1.000 57.29674  ? 317 THR A HG22 1 
ATOM   4813 H HG23 . THR A 1 325 ? -7.35297  0.03907   -12.66157 1.000 57.29674  ? 317 THR A HG23 1 
ATOM   4814 N N    . ASN A 1 326 ? -3.76669  2.16202   -14.80303 1.000 32.50315  ? 318 ASN A N    1 
ATOM   4815 C CA   . ASN A 1 326 ? -2.75727  2.95449   -15.48287 1.000 42.03275  ? 318 ASN A CA   1 
ATOM   4816 C C    . ASN A 1 326 ? -1.44967  2.83907   -14.71403 1.000 26.15267  ? 318 ASN A C    1 
ATOM   4817 O O    . ASN A 1 326 ? -1.46144  2.60511   -13.50301 1.000 27.81311  ? 318 ASN A O    1 
ATOM   4818 C CB   . ASN A 1 326 ? -3.17260  4.42889   -15.58581 1.000 36.37464  ? 318 ASN A CB   1 
ATOM   4819 C CG   . ASN A 1 326 ? -4.56827  4.59854   -16.14997 1.000 47.02121  ? 318 ASN A CG   1 
ATOM   4820 O OD1  . ASN A 1 326 ? -4.81609  4.30225   -17.31798 1.000 45.03651  ? 318 ASN A OD1  1 
ATOM   4821 N ND2  . ASN A 1 326 ? -5.49024  5.07175   -15.31954 1.000 51.06232  ? 318 ASN A ND2  1 
ATOM   4822 H H    . ASN A 1 326 ? -3.80766  2.33724   -13.96207 1.000 39.02080  ? 318 ASN A H    1 
ATOM   4823 H HA   . ASN A 1 326 ? -2.62536  2.62758   -16.38654 1.000 50.45632  ? 318 ASN A HA   1 
ATOM   4824 H HB2  . ASN A 1 326 ? -3.15497  4.82603   -14.70101 1.000 43.66659  ? 318 ASN A HB2  1 
ATOM   4825 H HB3  . ASN A 1 326 ? -2.55295  4.89303   -16.17019 1.000 43.66659  ? 318 ASN A HB3  1 
ATOM   4826 H HD21 . ASN A 1 326 ? -6.29756  5.18571   -15.59314 1.000 61.29181  ? 318 ASN A HD21 1 
ATOM   4827 H HD22 . ASN A 1 326 ? -5.27999  5.26423   -14.50815 1.000 61.29181  ? 318 ASN A HD22 1 
ATOM   4828 N N    . PRO A 1 327 ? -0.31194  2.97363   -15.38632 1.000 29.48773  ? 319 PRO A N    1 
ATOM   4829 C CA   . PRO A 1 327 ? 0.97987   2.84885   -14.68419 1.000 26.27450  ? 319 PRO A CA   1 
ATOM   4830 C C    . PRO A 1 327 ? 1.01069   3.72143   -13.44294 1.000 32.38493  ? 319 PRO A C    1 
ATOM   4831 O O    . PRO A 1 327 ? 0.48063   4.84371   -13.45216 1.000 33.88677  ? 319 PRO A O    1 
ATOM   4832 C CB   . PRO A 1 327 ? 1.99954   3.32048   -15.73028 1.000 29.52825  ? 319 PRO A CB   1 
ATOM   4833 C CG   . PRO A 1 327 ? 1.33510   3.02217   -17.05288 1.000 35.78319  ? 319 PRO A CG   1 
ATOM   4834 C CD   . PRO A 1 327 ? -0.14531  3.24693   -16.82664 1.000 42.46708  ? 319 PRO A CD   1 
ATOM   4835 H HA   . PRO A 1 327 ? 1.16012   1.92682   -14.44278 1.000 31.54642  ? 319 PRO A HA   1 
ATOM   4836 H HB2  . PRO A 1 327 ? 2.16677   4.27054   -15.62863 1.000 35.45093  ? 319 PRO A HB2  1 
ATOM   4837 H HB3  . PRO A 1 327 ? 2.82840   2.82568   -15.63513 1.000 35.45093  ? 319 PRO A HB3  1 
ATOM   4838 H HG2  . PRO A 1 327 ? 1.67459   3.62412   -17.73355 1.000 42.95686  ? 319 PRO A HG2  1 
ATOM   4839 H HG3  . PRO A 1 327 ? 1.50873   2.10229   -17.30699 1.000 42.95686  ? 319 PRO A HG3  1 
ATOM   4840 H HD2  . PRO A 1 327 ? -0.39180  4.16154   -17.03553 1.000 50.97752  ? 319 PRO A HD2  1 
ATOM   4841 H HD3  . PRO A 1 327 ? -0.67349  2.63126   -17.35850 1.000 50.97752  ? 319 PRO A HD3  1 
ATOM   4842 N N    . PRO A 1 328 ? 1.59621   3.23601   -12.34712 1.000 28.29213  ? 320 PRO A N    1 
ATOM   4843 C CA   . PRO A 1 328 ? 1.71702   4.07612   -11.14968 1.000 23.57982  ? 320 PRO A CA   1 
ATOM   4844 C C    . PRO A 1 328 ? 2.37074   5.40788   -11.48039 1.000 28.68651  ? 320 PRO A C    1 
ATOM   4845 O O    . PRO A 1 328 ? 3.28321   5.48169   -12.30784 1.000 22.19674  ? 320 PRO A O    1 
ATOM   4846 C CB   . PRO A 1 328 ? 2.59907   3.24152   -10.21601 1.000 25.89126  ? 320 PRO A CB   1 
ATOM   4847 C CG   . PRO A 1 328 ? 2.47264   1.85536   -10.69536 1.000 22.77757  ? 320 PRO A CG   1 
ATOM   4848 C CD   . PRO A 1 328 ? 2.17142   1.89095   -12.14952 1.000 22.75418  ? 320 PRO A CD   1 
ATOM   4849 H HA   . PRO A 1 328 ? 0.84869   4.22121   -10.74244 1.000 28.31281  ? 320 PRO A HA   1 
ATOM   4850 H HB2  . PRO A 1 328 ? 3.51853   3.54500   -10.27422 1.000 31.08654  ? 320 PRO A HB2  1 
ATOM   4851 H HB3  . PRO A 1 328 ? 2.28021   3.32226   -9.30348  1.000 31.08654  ? 320 PRO A HB3  1 
ATOM   4852 H HG2  . PRO A 1 328 ? 3.30789   1.38791   -10.53805 1.000 27.35011  ? 320 PRO A HG2  1 
ATOM   4853 H HG3  . PRO A 1 328 ? 1.75220   1.41812   -10.21506 1.000 27.35011  ? 320 PRO A HG3  1 
ATOM   4854 H HD2  . PRO A 1 328 ? 2.98130   1.78211   -12.67216 1.000 27.32204  ? 320 PRO A HD2  1 
ATOM   4855 H HD3  . PRO A 1 328 ? 1.52933   1.20327   -12.38556 1.000 27.32204  ? 320 PRO A HD3  1 
ATOM   4856 N N    . LYS A 1 329 ? 1.89644   6.46386   -10.81850 1.000 26.89775  ? 321 LYS A N    1 
ATOM   4857 C CA   . LYS A 1 329 ? 2.47068   7.80245   -10.94655 1.000 28.81957  ? 321 LYS A CA   1 
ATOM   4858 C C    . LYS A 1 329 ? 3.75515   7.84437   -10.12705 1.000 24.80807  ? 321 LYS A C    1 
ATOM   4859 O O    . LYS A 1 329 ? 3.72148   7.95662   -8.89914  1.000 35.35592  ? 321 LYS A O    1 
ATOM   4860 C CB   . LYS A 1 329 ? 1.48214   8.86193   -10.47094 1.000 33.65801  ? 321 LYS A CB   1 
ATOM   4861 C CG   . LYS A 1 329 ? 0.12438   8.81086   -11.15204 1.000 45.77117  ? 321 LYS A CG   1 
ATOM   4862 C CD   . LYS A 1 329 ? 0.02523   9.83620   -12.27376 1.000 44.12446  ? 321 LYS A CD   1 
ATOM   4863 C CE   . LYS A 1 329 ? -1.40792  9.99725   -12.76129 1.000 62.67953  ? 321 LYS A CE   1 
ATOM   4864 N NZ   . LYS A 1 329 ? -1.83184  8.86289   -13.63880 1.000 63.48936  ? 321 LYS A NZ   1 
ATOM   4865 H H    . LYS A 1 329 ? 1.22851   6.42935   -10.27787 1.000 32.29432  ? 321 LYS A H    1 
ATOM   4866 H HA   . LYS A 1 329 ? 2.68215   7.97779   -11.87684 1.000 34.60051  ? 321 LYS A HA   1 
ATOM   4867 H HB2  . LYS A 1 329 ? 1.33678   8.74330   -9.51926  1.000 40.40664  ? 321 LYS A HB2  1 
ATOM   4868 H HB3  . LYS A 1 329 ? 1.86249   9.73774   -10.64182 1.000 40.40664  ? 321 LYS A HB3  1 
ATOM   4869 H HG2  . LYS A 1 329 ? -0.01173  7.92883   -11.53204 1.000 54.94243  ? 321 LYS A HG2  1 
ATOM   4870 H HG3  . LYS A 1 329 ? -0.56909  9.00242   -10.50142 1.000 54.94243  ? 321 LYS A HG3  1 
ATOM   4871 H HD2  . LYS A 1 329 ? 0.33519   10.69657  -11.95035 1.000 52.96638  ? 321 LYS A HD2  1 
ATOM   4872 H HD3  . LYS A 1 329 ? 0.57056   9.54695   -13.02199 1.000 52.96638  ? 321 LYS A HD3  1 
ATOM   4873 H HE2  . LYS A 1 329 ? -2.00377  10.02768  -11.99648 1.000 75.23246  ? 321 LYS A HE2  1 
ATOM   4874 H HE3  . LYS A 1 329 ? -1.48105  10.81883  -13.27173 1.000 75.23246  ? 321 LYS A HE3  1 
ATOM   4875 H HZ1  . LYS A 1 329 ? -2.67293  8.98148   -13.90453 1.000 76.20425  ? 321 LYS A HZ1  1 
ATOM   4876 H HZ2  . LYS A 1 329 ? -1.30592  8.81944   -14.35547 1.000 76.20425  ? 321 LYS A HZ2  1 
ATOM   4877 H HZ3  . LYS A 1 329 ? -1.77555  8.09510   -13.19224 1.000 76.20425  ? 321 LYS A HZ3  1 
ATOM   4878 N N    . LEU A 1 330 ? 4.89839   7.74725   -10.80449 1.000 22.89912  ? 322 LEU A N    1 
ATOM   4879 C CA   . LEU A 1 330 ? 6.18723   7.71721   -10.13071 1.000 23.01130  ? 322 LEU A CA   1 
ATOM   4880 C C    . LEU A 1 330 ? 6.95497   9.03004   -10.22757 1.000 23.72037  ? 322 LEU A C    1 
ATOM   4881 O O    . LEU A 1 330 ? 7.91027   9.22335   -9.46830  1.000 19.62201  ? 322 LEU A O    1 
ATOM   4882 C CB   . LEU A 1 330 ? 7.05267   6.58786   -10.71022 1.000 18.60111  ? 322 LEU A CB   1 
ATOM   4883 C CG   . LEU A 1 330 ? 6.46034   5.17113   -10.66196 1.000 16.40185  ? 322 LEU A CG   1 
ATOM   4884 C CD1  . LEU A 1 330 ? 7.48246   4.18058   -11.16471 1.000 21.65089  ? 322 LEU A CD1  1 
ATOM   4885 C CD2  . LEU A 1 330 ? 6.02455   4.81109   -9.25452  1.000 19.78326  ? 322 LEU A CD2  1 
ATOM   4886 H H    . LEU A 1 330 ? 4.95054   7.69717   -11.66145 1.000 27.49597  ? 322 LEU A H    1 
ATOM   4887 H HA   . LEU A 1 330 ? 6.04189   7.53465   -9.18919  1.000 27.63059  ? 322 LEU A HA   1 
ATOM   4888 H HB2  . LEU A 1 330 ? 7.22654   6.79171   -11.64249 1.000 22.33836  ? 322 LEU A HB2  1 
ATOM   4889 H HB3  . LEU A 1 330 ? 7.88620   6.56455   -10.21467 1.000 22.33836  ? 322 LEU A HB3  1 
ATOM   4890 H HG   . LEU A 1 330 ? 5.67477   5.13286   -11.22969 1.000 19.69924  ? 322 LEU A HG   1 
ATOM   4891 H HD11 . LEU A 1 330 ? 7.10270   3.28877   -11.12787 1.000 25.99809  ? 322 LEU A HD11 1 
ATOM   4892 H HD12 . LEU A 1 330 ? 7.71492   4.40357   -12.07966 1.000 25.99809  ? 322 LEU A HD12 1 
ATOM   4893 H HD13 . LEU A 1 330 ? 8.27124   4.22771   -10.60213 1.000 25.99809  ? 322 LEU A HD13 1 
ATOM   4894 H HD21 . LEU A 1 330 ? 5.74564   3.88220   -9.23817  1.000 23.75694  ? 322 LEU A HD21 1 
ATOM   4895 H HD22 . LEU A 1 330 ? 6.77102   4.94302   -8.64932  1.000 23.75694  ? 322 LEU A HD22 1 
ATOM   4896 H HD23 . LEU A 1 330 ? 5.28477   5.38317   -8.99692  1.000 23.75694  ? 322 LEU A HD23 1 
ATOM   4897 N N    . LYS A 1 331 ? 6.57674   9.93419   -11.13183 1.000 24.90482  ? 323 LYS A N    1 
ATOM   4898 C CA   . LYS A 1 331 ? 7.36406   11.14483  -11.32361 1.000 24.39867  ? 323 LYS A CA   1 
ATOM   4899 C C    . LYS A 1 331 ? 7.42971   11.95057  -10.03268 1.000 19.67671  ? 323 LYS A C    1 
ATOM   4900 O O    . LYS A 1 331 ? 6.40129   12.24928  -9.41879  1.000 23.48788  ? 323 LYS A O    1 
ATOM   4901 C CB   . LYS A 1 331 ? 6.77852   12.00618  -12.44658 1.000 23.61146  ? 323 LYS A CB   1 
ATOM   4902 C CG   . LYS A 1 331 ? 7.61262   13.25817  -12.70417 1.000 36.91029  ? 323 LYS A CG   1 
ATOM   4903 C CD   . LYS A 1 331 ? 7.46445   13.76135  -14.12634 1.000 56.38458  ? 323 LYS A CD   1 
ATOM   4904 C CE   . LYS A 1 331 ? 8.59249   14.72662  -14.49406 1.000 49.31282  ? 323 LYS A CE   1 
ATOM   4905 N NZ   . LYS A 1 331 ? 9.95246   14.21214  -14.14008 1.000 61.60183  ? 323 LYS A NZ   1 
ATOM   4906 H H    . LYS A 1 331 ? 5.88245   9.86933   -11.63517 1.000 29.90281  ? 323 LYS A H    1 
ATOM   4907 H HA   . LYS A 1 331 ? 8.26434   10.89006  -11.57952 1.000 29.29543  ? 323 LYS A HA   1 
ATOM   4908 H HB2  . LYS A 1 331 ? 6.75123   11.48635  -13.26507 1.000 28.35077  ? 323 LYS A HB2  1 
ATOM   4909 H HB3  . LYS A 1 331 ? 5.88250   12.28422  -12.20011 1.000 28.35077  ? 323 LYS A HB3  1 
ATOM   4910 H HG2  . LYS A 1 331 ? 7.32423   13.96262  -12.10294 1.000 44.30937  ? 323 LYS A HG2  1 
ATOM   4911 H HG3  . LYS A 1 331 ? 8.54868   13.05452  -12.55180 1.000 44.30937  ? 323 LYS A HG3  1 
ATOM   4912 H HD2  . LYS A 1 331 ? 7.49350   13.00962  -14.73869 1.000 67.67852  ? 323 LYS A HD2  1 
ATOM   4913 H HD3  . LYS A 1 331 ? 6.61980   14.22979  -14.21595 1.000 67.67852  ? 323 LYS A HD3  1 
ATOM   4914 H HE2  . LYS A 1 331 ? 8.57338   14.88185  -15.45136 1.000 59.19240  ? 323 LYS A HE2  1 
ATOM   4915 H HE3  . LYS A 1 331 ? 8.45805   15.56200  -14.01975 1.000 59.19240  ? 323 LYS A HE3  1 
ATOM   4916 H HZ1  . LYS A 1 331 ? 10.57806  14.73965  -14.49003 1.000 73.93922  ? 323 LYS A HZ1  1 
ATOM   4917 H HZ2  . LYS A 1 331 ? 10.05074  14.19499  -13.25569 1.000 73.93922  ? 323 LYS A HZ2  1 
ATOM   4918 H HZ3  . LYS A 1 331 ? 10.05847  13.38785  -14.45852 1.000 73.93922  ? 323 LYS A HZ3  1 
ATOM   4919 N N    . GLY A 1 332 ? 8.64765   12.30526  -9.62823  1.000 21.20562  ? 324 GLY A N    1 
ATOM   4920 C CA   . GLY A 1 332 ? 8.84650   13.07051  -8.41552  1.000 23.51823  ? 324 GLY A CA   1 
ATOM   4921 C C    . GLY A 1 332 ? 8.56432   12.32576  -7.13357  1.000 27.04459  ? 324 GLY A C    1 
ATOM   4922 O O    . GLY A 1 332 ? 8.56565   12.95090  -6.06554  1.000 24.77532  ? 324 GLY A O    1 
ATOM   4923 H H    . GLY A 1 332 ? 9.37464   12.11116  -10.04466 1.000 25.46376  ? 324 GLY A H    1 
ATOM   4924 H HA2  . GLY A 1 332 ? 9.76893   13.36908  -8.38584  1.000 28.23890  ? 324 GLY A HA2  1 
ATOM   4925 H HA3  . GLY A 1 332 ? 8.26422   13.84592  -8.44002  1.000 28.23890  ? 324 GLY A HA3  1 
ATOM   4926 N N    . LYS A 1 333 ? 8.32878   11.01442  -7.20369  1.000 19.27624  ? 325 LYS A N    1 
ATOM   4927 C CA   . LYS A 1 333 ? 8.03298   10.18352  -6.04469  1.000 19.83471  ? 325 LYS A CA   1 
ATOM   4928 C C    . LYS A 1 333 ? 9.31216   9.53389   -5.54466  1.000 16.96160  ? 325 LYS A C    1 
ATOM   4929 O O    . LYS A 1 333 ? 10.12918  9.07130   -6.34573  1.000 18.38179  ? 325 LYS A O    1 
ATOM   4930 C CB   . LYS A 1 333 ? 7.02395   9.08660   -6.39579  1.000 17.79423  ? 325 LYS A CB   1 
ATOM   4931 C CG   . LYS A 1 333 ? 5.65480   9.58700   -6.81235  1.000 27.32074  ? 325 LYS A CG   1 
ATOM   4932 C CD   . LYS A 1 333 ? 5.01344   10.38260  -5.70008  1.000 29.77266  ? 325 LYS A CD   1 
ATOM   4933 C CE   . LYS A 1 333 ? 3.72034   11.03737  -6.17401  1.000 47.27445  ? 325 LYS A CE   1 
ATOM   4934 N NZ   . LYS A 1 333 ? 3.61486   12.44297  -5.69052  1.000 64.64392  ? 325 LYS A NZ   1 
ATOM   4935 H H    . LYS A 1 333 ? 8.33590   10.57069  -7.94034  1.000 23.14852  ? 325 LYS A H    1 
ATOM   4936 H HA   . LYS A 1 333 ? 7.65670   10.73712  -5.34266  1.000 23.81867  ? 325 LYS A HA   1 
ATOM   4937 H HB2  . LYS A 1 333 ? 7.38016   8.56595   -7.13263  1.000 21.37010  ? 325 LYS A HB2  1 
ATOM   4938 H HB3  . LYS A 1 333 ? 6.90256   8.52036   -5.61763  1.000 21.37010  ? 325 LYS A HB3  1 
ATOM   4939 H HG2  . LYS A 1 333 ? 5.74212   10.16017  -7.59001  1.000 32.80191  ? 325 LYS A HG2  1 
ATOM   4940 H HG3  . LYS A 1 333 ? 5.08295   8.83141   -7.01965  1.000 32.80191  ? 325 LYS A HG3  1 
ATOM   4941 H HD2  . LYS A 1 333 ? 4.80530   9.79258   -4.95883  1.000 35.74421  ? 325 LYS A HD2  1 
ATOM   4942 H HD3  . LYS A 1 333 ? 5.62183   11.07959  -5.40859  1.000 35.74421  ? 325 LYS A HD3  1 
ATOM   4943 H HE2  . LYS A 1 333 ? 3.70052   11.04544  -7.14378  1.000 56.74637  ? 325 LYS A HE2  1 
ATOM   4944 H HE3  . LYS A 1 333 ? 2.96259   10.53844  -5.83084  1.000 56.74637  ? 325 LYS A HE3  1 
ATOM   4945 H HZ1  . LYS A 1 333 ? 2.85858   12.80963  -5.98327  1.000 77.58973  ? 325 LYS A HZ1  1 
ATOM   4946 H HZ2  . LYS A 1 333 ? 3.61850   12.45988  -4.80069  1.000 77.58973  ? 325 LYS A HZ2  1 
ATOM   4947 H HZ3  . LYS A 1 333 ? 4.30284   12.92078  -5.99131  1.000 77.58973  ? 325 LYS A HZ3  1 
ATOM   4948 N N    . LYS A 1 334 ? 9.47561   9.48759   -4.21688  1.000 15.92951  ? 326 LYS A N    1 
ATOM   4949 C CA   . LYS A 1 334 ? 10.61853  8.83165   -3.59381  1.000 16.63914  ? 326 LYS A CA   1 
ATOM   4950 C C    . LYS A 1 334 ? 10.30358  7.35302   -3.39951  1.000 11.98926  ? 326 LYS A C    1 
ATOM   4951 O O    . LYS A 1 334 ? 9.26918   7.00335   -2.81673  1.000 14.17594  ? 326 LYS A O    1 
ATOM   4952 C CB   . LYS A 1 334 ? 10.95147  9.47734   -2.24901  1.000 16.80196  ? 326 LYS A CB   1 
ATOM   4953 C CG   . LYS A 1 334 ? 12.13791  8.89031   -1.54264  1.000 16.92775  ? 326 LYS A CG   1 
ATOM   4954 C CD   . LYS A 1 334 ? 12.42008  9.69466   -0.25827  1.000 18.89271  ? 326 LYS A CD   1 
ATOM   4955 C CE   . LYS A 1 334 ? 13.48172  9.04663   0.59974   1.000 25.86115  ? 326 LYS A CE   1 
ATOM   4956 N NZ   . LYS A 1 334 ? 13.85385  9.94130   1.75072   1.000 18.83481  ? 326 LYS A NZ   1 
ATOM   4957 H H    . LYS A 1 334 ? 8.92754   9.83523   -3.65263  1.000 19.13244  ? 326 LYS A H    1 
ATOM   4958 H HA   . LYS A 1 334 ? 11.39508  8.91732   -4.16874  1.000 19.98399  ? 326 LYS A HA   1 
ATOM   4959 H HB2  . LYS A 1 334 ? 11.13677  10.41787  -2.39718  1.000 20.17937  ? 326 LYS A HB2  1 
ATOM   4960 H HB3  . LYS A 1 334 ? 10.18516  9.37854   -1.66257  1.000 20.17937  ? 326 LYS A HB3  1 
ATOM   4961 H HG2  . LYS A 1 334 ? 11.95460  7.96882   -1.30150  1.000 20.33032  ? 326 LYS A HG2  1 
ATOM   4962 H HG3  . LYS A 1 334 ? 12.91796  8.93391   -2.11754  1.000 20.33032  ? 326 LYS A HG3  1 
ATOM   4963 H HD2  . LYS A 1 334 ? 12.72731  10.58255  -0.49943  1.000 22.68827  ? 326 LYS A HD2  1 
ATOM   4964 H HD3  . LYS A 1 334 ? 11.60538  9.75614   0.26460   1.000 22.68827  ? 326 LYS A HD3  1 
ATOM   4965 H HE2  . LYS A 1 334 ? 13.14450  8.20982   0.95600   1.000 31.05040  ? 326 LYS A HE2  1 
ATOM   4966 H HE3  . LYS A 1 334 ? 14.27532  8.88423   0.06616   1.000 31.05040  ? 326 LYS A HE3  1 
ATOM   4967 H HZ1  . LYS A 1 334 ? 14.27839  9.47176   2.37634   1.000 22.61880  ? 326 LYS A HZ1  1 
ATOM   4968 H HZ2  . LYS A 1 334 ? 14.38776  10.59483  1.46801   1.000 22.61880  ? 326 LYS A HZ2  1 
ATOM   4969 H HZ3  . LYS A 1 334 ? 13.12126  10.30032  2.10641   1.000 22.61880  ? 326 LYS A HZ3  1 
ATOM   4970 N N    . ILE A 1 335 ? 11.20116  6.49289   -3.87774  1.000 12.00016  ? 327 ILE A N    1 
ATOM   4971 C CA   . ILE A 1 335 ? 10.99137  5.05194   -3.85819  1.000 11.33927  ? 327 ILE A CA   1 
ATOM   4972 C C    . ILE A 1 335 ? 12.21545  4.39128   -3.26068  1.000 10.24033  ? 327 ILE A C    1 
ATOM   4973 O O    . ILE A 1 335 ? 13.34741  4.65803   -3.69162  1.000 12.35092  ? 327 ILE A O    1 
ATOM   4974 C CB   . ILE A 1 335 ? 10.70361  4.49970   -5.26684  1.000 11.92451  ? 327 ILE A CB   1 
ATOM   4975 C CG1  . ILE A 1 335 ? 10.46978  2.99405   -5.20103  1.000 11.05728  ? 327 ILE A CG1  1 
ATOM   4976 C CG2  . ILE A 1 335 ? 11.83115  4.79438   -6.22196  1.000 20.54316  ? 327 ILE A CG2  1 
ATOM   4977 C CD1  . ILE A 1 335 ? 9.72228   2.43377   -6.39692  1.000 20.92882  ? 327 ILE A CD1  1 
ATOM   4978 H H    . ILE A 1 335 ? 11.95239  6.72763   -4.22437  1.000 14.41721  ? 327 ILE A H    1 
ATOM   4979 H HA   . ILE A 1 335 ? 10.23362  4.84639   -3.28858  1.000 13.62414  ? 327 ILE A HA   1 
ATOM   4980 H HB   . ILE A 1 335 ? 9.90512   4.94243   -5.59440  1.000 14.32643  ? 327 ILE A HB   1 
ATOM   4981 H HG12 . ILE A 1 335 ? 11.32958  2.54741   -5.15460  1.000 13.28575  ? 327 ILE A HG12 1 
ATOM   4982 H HG13 . ILE A 1 335 ? 9.94898   2.79448   -4.40740  1.000 13.28575  ? 327 ILE A HG13 1 
ATOM   4983 H HG21 . ILE A 1 335 ? 11.55224  4.56138   -7.12131  1.000 24.66881  ? 327 ILE A HG21 1 
ATOM   4984 H HG22 . ILE A 1 335 ? 12.04485  5.73945   -6.17631  1.000 24.66881  ? 327 ILE A HG22 1 
ATOM   4985 H HG23 . ILE A 1 335 ? 12.60530  4.26759   -5.96880  1.000 24.66881  ? 327 ILE A HG23 1 
ATOM   4986 H HD11 . ILE A 1 335 ? 9.54227   1.49291   -6.24434  1.000 25.13160  ? 327 ILE A HD11 1 
ATOM   4987 H HD12 . ILE A 1 335 ? 8.88803   2.91725   -6.50271  1.000 25.13160  ? 327 ILE A HD12 1 
ATOM   4988 H HD13 . ILE A 1 335 ? 10.26985  2.54137   -7.19032  1.000 25.13160  ? 327 ILE A HD13 1 
ATOM   4989 N N    . LEU A 1 336 ? 11.98652  3.53054   -2.27409  1.000 11.84739  ? 328 LEU A N    1 
ATOM   4990 C CA   . LEU A 1 336 ? 13.03593  2.74315   -1.65276  1.000 11.96246  ? 328 LEU A CA   1 
ATOM   4991 C C    . LEU A 1 336 ? 13.08562  1.37678   -2.31309  1.000 11.60194  ? 328 LEU A C    1 
ATOM   4992 O O    . LEU A 1 336 ? 12.10943  0.61533   -2.24499  1.000 12.61018  ? 328 LEU A O    1 
ATOM   4993 C CB   . LEU A 1 336 ? 12.78573  2.58468   -0.15803  1.000 11.03185  ? 328 LEU A CB   1 
ATOM   4994 C CG   . LEU A 1 336 ? 12.42114  3.83267   0.64032   1.000 14.47990  ? 328 LEU A CG   1 
ATOM   4995 C CD1  . LEU A 1 336 ? 12.24617  3.44953   2.11235   1.000 17.25232  ? 328 LEU A CD1  1 
ATOM   4996 C CD2  . LEU A 1 336 ? 13.49874  4.90047   0.48119   1.000 14.45406  ? 328 LEU A CD2  1 
ATOM   4997 H H    . LEU A 1 336 ? 11.20759  3.38365   -1.94048  1.000 14.23389  ? 328 LEU A H    1 
ATOM   4998 H HA   . LEU A 1 336 ? 13.88737  3.18945   -1.78219  1.000 14.37197  ? 328 LEU A HA   1 
ATOM   4999 H HB2  . LEU A 1 336 ? 12.05373  1.95811   -0.04623  1.000 13.25525  ? 328 LEU A HB2  1 
ATOM   5000 H HB3  . LEU A 1 336 ? 13.59396  2.22505   0.23988   1.000 13.25525  ? 328 LEU A HB3  1 
ATOM   5001 H HG   . LEU A 1 336 ? 11.58917  4.20847   0.31246   1.000 17.39290  ? 328 LEU A HG   1 
ATOM   5002 H HD11 . LEU A 1 336 ? 12.03822  4.24713   2.62371   1.000 20.71981  ? 328 LEU A HD11 1 
ATOM   5003 H HD12 . LEU A 1 336 ? 11.52110  2.80966   2.18809   1.000 20.71981  ? 328 LEU A HD12 1 
ATOM   5004 H HD13 . LEU A 1 336 ? 13.07092  3.05472   2.43610   1.000 20.71981  ? 328 LEU A HD13 1 
ATOM   5005 H HD21 . LEU A 1 336 ? 13.27154  5.66347   1.03536   1.000 17.36190  ? 328 LEU A HD21 1 
ATOM   5006 H HD22 . LEU A 1 336 ? 14.35189  4.53205   0.75923   1.000 17.36190  ? 328 LEU A HD22 1 
ATOM   5007 H HD23 . LEU A 1 336 ? 13.54209  5.16909   -0.44987  1.000 17.36190  ? 328 LEU A HD23 1 
ATOM   5008 N N    . VAL A 1 337 ? 14.20982  1.08169   -2.96031  1.000 10.74793  ? 329 VAL A N    1 
ATOM   5009 C CA   . VAL A 1 337 ? 14.43351  -0.19180  -3.63689  1.000 12.47215  ? 329 VAL A CA   1 
ATOM   5010 C C    . VAL A 1 337 ? 15.26140  -1.06607  -2.70245  1.000 16.51429  ? 329 VAL A C    1 
ATOM   5011 O O    . VAL A 1 337 ? 16.38642  -0.70608  -2.33396  1.000 12.77728  ? 329 VAL A O    1 
ATOM   5012 C CB   . VAL A 1 337 ? 15.13643  -0.00282  -4.99276  1.000 11.89978  ? 329 VAL A CB   1 
ATOM   5013 C CG1  . VAL A 1 337 ? 15.37632  -1.35345  -5.64346  1.000 14.60095  ? 329 VAL A CG1  1 
ATOM   5014 C CG2  . VAL A 1 337 ? 14.33031  0.91797   -5.89046  1.000 13.21328  ? 329 VAL A CG2  1 
ATOM   5015 H H    . VAL A 1 337 ? 14.87756  1.62003   -3.02293  1.000 12.91454  ? 329 VAL A H    1 
ATOM   5016 H HA   . VAL A 1 337 ? 13.58211  -0.62606  -3.80254  1.000 14.98360  ? 329 VAL A HA   1 
ATOM   5017 H HB   . VAL A 1 337 ? 15.99932  0.41831   -4.85503  1.000 14.29676  ? 329 VAL A HB   1 
ATOM   5018 H HG11 . VAL A 1 337 ? 15.72517  -1.21553  -6.53799  1.000 17.53816  ? 329 VAL A HG11 1 
ATOM   5019 H HG12 . VAL A 1 337 ? 16.01708  -1.85088  -5.11159  1.000 17.53816  ? 329 VAL A HG12 1 
ATOM   5020 H HG13 . VAL A 1 337 ? 14.53641  -1.83674  -5.68684  1.000 17.53816  ? 329 VAL A HG13 1 
ATOM   5021 H HG21 . VAL A 1 337 ? 14.78874  1.01144   -6.74017  1.000 15.87296  ? 329 VAL A HG21 1 
ATOM   5022 H HG22 . VAL A 1 337 ? 13.45094  0.53295   -6.02964  1.000 15.87296  ? 329 VAL A HG22 1 
ATOM   5023 H HG23 . VAL A 1 337 ? 14.24806  1.78428   -5.46194  1.000 15.87296  ? 329 VAL A HG23 1 
ATOM   5024 N N    . ILE A 1 338 ? 14.70920  -2.20511  -2.29148  1.000 10.34242  ? 330 ILE A N    1 
ATOM   5025 C CA   . ILE A 1 338 ? 15.37615  -3.08509  -1.33121  1.000 11.86530  ? 330 ILE A CA   1 
ATOM   5026 C C    . ILE A 1 338 ? 15.78928  -4.38114  -2.02490  1.000 17.96392  ? 330 ILE A C    1 
ATOM   5027 O O    . ILE A 1 338 ? 14.96765  -5.04430  -2.66718  1.000 14.89150  ? 330 ILE A O    1 
ATOM   5028 C CB   . ILE A 1 338 ? 14.47087  -3.36366  -0.11503  1.000 14.04946  ? 330 ILE A CB   1 
ATOM   5029 C CG1  . ILE A 1 338 ? 14.12707  -2.04669  0.60309   1.000 15.93440  ? 330 ILE A CG1  1 
ATOM   5030 C CG2  . ILE A 1 338 ? 15.12555  -4.33779  0.85709   1.000 16.01154  ? 330 ILE A CG2  1 
ATOM   5031 C CD1  . ILE A 1 338 ? 13.04743  -2.18755  1.65736   1.000 24.97194  ? 330 ILE A CD1  1 
ATOM   5032 H H    . ILE A 1 338 ? 13.94304  -2.49220  -2.55640  1.000 12.42793  ? 330 ILE A H    1 
ATOM   5033 H HA   . ILE A 1 338 ? 16.18955  -2.65500  -1.02412  1.000 14.25538  ? 330 ILE A HA   1 
ATOM   5034 H HB   . ILE A 1 338 ? 13.65427  -3.77176  -0.44292  1.000 16.87637  ? 330 ILE A HB   1 
ATOM   5035 H HG12 . ILE A 1 338 ? 14.92578  -1.71267  1.04057   1.000 19.13830  ? 330 ILE A HG12 1 
ATOM   5036 H HG13 . ILE A 1 338 ? 13.81615  -1.40513  -0.05467  1.000 19.13830  ? 330 ILE A HG13 1 
ATOM   5037 H HG21 . ILE A 1 338 ? 14.54961  -4.44780  1.62981   1.000 19.23087  ? 330 ILE A HG21 1 
ATOM   5038 H HG22 . ILE A 1 338 ? 15.25004  -5.19121  0.41315   1.000 19.23087  ? 330 ILE A HG22 1 
ATOM   5039 H HG23 . ILE A 1 338 ? 15.98399  -3.97994  1.13264   1.000 19.23087  ? 330 ILE A HG23 1 
ATOM   5040 H HD11 . ILE A 1 338 ? 12.81004  -1.30633  1.98599   1.000 29.98335  ? 330 ILE A HD11 1 
ATOM   5041 H HD12 . ILE A 1 338 ? 12.27134  -2.61246  1.25981   1.000 29.98335  ? 330 ILE A HD12 1 
ATOM   5042 H HD13 . ILE A 1 338 ? 13.38599  -2.73193  2.38532   1.000 29.98335  ? 330 ILE A HD13 1 
ATOM   5043 N N    . ASP A 1 339 ? 17.05814  -4.75880  -1.87635  1.000 14.26885  ? 331 ASP A N    1 
ATOM   5044 C CA   . ASP A 1 339 ? 17.55865  -6.03091  -2.38466  1.000 10.80737  ? 331 ASP A CA   1 
ATOM   5045 C C    . ASP A 1 339 ? 18.39641  -6.69092  -1.29530  1.000 13.92148  ? 331 ASP A C    1 
ATOM   5046 O O    . ASP A 1 339 ? 18.74375  -6.06996  -0.28337  1.000 14.37889  ? 331 ASP A O    1 
ATOM   5047 C CB   . ASP A 1 339 ? 18.37354  -5.83476  -3.66698  1.000 15.20827  ? 331 ASP A CB   1 
ATOM   5048 C CG   . ASP A 1 339 ? 18.33285  -7.04519  -4.59365  1.000 20.99874  ? 331 ASP A CG   1 
ATOM   5049 O OD1  . ASP A 1 339 ? 17.67582  -8.06436  -4.26327  1.000 22.15506  ? 331 ASP A OD1  1 
ATOM   5050 O OD2  . ASP A 1 339 ? 18.97627  -6.95435  -5.65554  1.000 22.26341  ? 331 ASP A OD2  1 
ATOM   5051 H H    . ASP A 1 339 ? 17.65605  -4.28615  -1.47796  1.000 17.13964  ? 331 ASP A H    1 
ATOM   5052 H HA   . ASP A 1 339 ? 16.81905  -6.62128  -2.59764  1.000 12.98586  ? 331 ASP A HA   1 
ATOM   5053 H HB2  . ASP A 1 339 ? 18.01719  -5.07475  -4.15309  1.000 18.26694  ? 331 ASP A HB2  1 
ATOM   5054 H HB3  . ASP A 1 339 ? 19.29978  -5.67192  -3.42937  1.000 18.26694  ? 331 ASP A HB3  1 
ATOM   5055 N N    . ASP A 1 340 ? 18.72149  -7.96906  -1.48858  1.000 11.96818  ? 332 ASP A N    1 
ATOM   5056 C CA   . ASP A 1 340 ? 19.44482  -8.66407  -0.43089  1.000 14.40427  ? 332 ASP A CA   1 
ATOM   5057 C C    . ASP A 1 340 ? 20.94117  -8.36872  -0.47774  1.000 15.82258  ? 332 ASP A C    1 
ATOM   5058 O O    . ASP A 1 340 ? 21.52443  -7.92549  0.52061   1.000 17.35090  ? 332 ASP A O    1 
ATOM   5059 C CB   . ASP A 1 340 ? 19.18933  -10.17060 -0.48826  1.000 21.23303  ? 332 ASP A CB   1 
ATOM   5060 C CG   . ASP A 1 340 ? 19.31075  -10.76968 -1.88605  1.000 17.29105  ? 332 ASP A CG   1 
ATOM   5061 O OD1  . ASP A 1 340 ? 19.67516  -10.09484 -2.86275  1.000 19.13038  ? 332 ASP A OD1  1 
ATOM   5062 O OD2  . ASP A 1 340 ? 19.01964  -11.98543 -1.99473  1.000 30.56674  ? 332 ASP A OD2  1 
ATOM   5063 H H    . ASP A 1 340 ? 18.54249  -8.43270  -2.19043  1.000 14.37883  ? 332 ASP A H    1 
ATOM   5064 H HA   . ASP A 1 340 ? 19.10362  -8.34285  0.41841   1.000 17.30214  ? 332 ASP A HA   1 
ATOM   5065 H HB2  . ASP A 1 340 ? 19.83550  -10.61751 0.08063   1.000 25.49666  ? 332 ASP A HB2  1 
ATOM   5066 H HB3  . ASP A 1 340 ? 18.28993  -10.34586 -0.17004  1.000 25.49666  ? 332 ASP A HB3  1 
ATOM   5067 N N    . PHE A 1 341 ? 21.58481  -8.63362  -1.61262  1.000 15.31079  ? 333 PHE A N    1 
ATOM   5068 C CA   . PHE A 1 341 ? 23.02714  -8.44918  -1.74876  1.000 20.87068  ? 333 PHE A CA   1 
ATOM   5069 C C    . PHE A 1 341 ? 23.34852  -7.33903  -2.74261  1.000 25.01520  ? 333 PHE A C    1 
ATOM   5070 O O    . PHE A 1 341 ? 22.69659  -7.21423  -3.78632  1.000 23.47543  ? 333 PHE A O    1 
ATOM   5071 C CB   . PHE A 1 341 ? 23.73358  -9.73152  -2.23322  1.000 21.04118  ? 333 PHE A CB   1 
ATOM   5072 C CG   . PHE A 1 341 ? 23.68995  -10.86833 -1.26692  1.000 20.45200  ? 333 PHE A CG   1 
ATOM   5073 C CD1  . PHE A 1 341 ? 24.62845  -10.96676 -0.25685  1.000 22.13762  ? 333 PHE A CD1  1 
ATOM   5074 C CD2  . PHE A 1 341 ? 22.71896  -11.84446 -1.36671  1.000 21.55644  ? 333 PHE A CD2  1 
ATOM   5075 C CE1  . PHE A 1 341 ? 24.60282  -12.00787 0.63659   1.000 26.76613  ? 333 PHE A CE1  1 
ATOM   5076 C CE2  . PHE A 1 341 ? 22.68368  -12.89075 -0.46020  1.000 36.69363  ? 333 PHE A CE2  1 
ATOM   5077 C CZ   . PHE A 1 341 ? 23.63572  -12.97068 0.54055   1.000 34.47011  ? 333 PHE A CZ   1 
ATOM   5078 H H    . PHE A 1 341 ? 21.20234  -8.92472  -2.32576  1.000 18.38997  ? 333 PHE A H    1 
ATOM   5079 H HA   . PHE A 1 341 ? 23.36748  -8.20449  -0.87400  1.000 25.06183  ? 333 PHE A HA   1 
ATOM   5080 H HB2  . PHE A 1 341 ? 23.30737  -10.02780 -3.05265  1.000 25.26644  ? 333 PHE A HB2  1 
ATOM   5081 H HB3  . PHE A 1 341 ? 24.66660  -9.52545  -2.40029  1.000 25.26644  ? 333 PHE A HB3  1 
ATOM   5082 H HD1  . PHE A 1 341 ? 25.28865  -10.31610 -0.18151  1.000 26.58216  ? 333 PHE A HD1  1 
ATOM   5083 H HD2  . PHE A 1 341 ? 22.08541  -11.79920 -2.04603  1.000 25.88475  ? 333 PHE A HD2  1 
ATOM   5084 H HE1  . PHE A 1 341 ? 25.24386  -12.05905 1.30842   1.000 32.13638  ? 333 PHE A HE1  1 
ATOM   5085 H HE2  . PHE A 1 341 ? 22.02031  -13.53942 -0.52407  1.000 44.04937  ? 333 PHE A HE2  1 
ATOM   5086 H HZ   . PHE A 1 341 ? 23.61827  -13.67650 1.14586   1.000 41.38116  ? 333 PHE A HZ   1 
ATOM   5087 N N    . CYS A 1 342 ? 24.37280  -6.54516  -2.42579  1.000 16.28498  ? 334 CYS A N    1 
ATOM   5088 C CA   . CYS A 1 342 ? 24.96570  -5.60658  -3.36963  1.000 14.52714  ? 334 CYS A CA   1 
ATOM   5089 C C    . CYS A 1 342 ? 26.44523  -5.94613  -3.48286  1.000 19.53922  ? 334 CYS A C    1 
ATOM   5090 O O    . CYS A 1 342 ? 27.18212  -5.85592  -2.49459  1.000 16.80691  ? 334 CYS A O    1 
ATOM   5091 C CB   . CYS A 1 342 ? 24.77603  -4.15589  -2.92728  1.000 21.54079  ? 334 CYS A CB   1 
ATOM   5092 S SG   . CYS A 1 342 ? 25.49040  -2.94084  -4.08350  1.000 20.96259  ? 334 CYS A SG   1 
ATOM   5093 H H    . CYS A 1 342 ? 24.74718  -6.53479  -1.65162  1.000 19.55900  ? 334 CYS A H    1 
ATOM   5094 H HA   . CYS A 1 342 ? 24.54311  -5.70133  -4.23758  1.000 17.44960  ? 334 CYS A HA   1 
ATOM   5095 H HB2  . CYS A 1 342 ? 23.82617  -3.97333  -2.85419  1.000 25.86597  ? 334 CYS A HB2  1 
ATOM   5096 H HB3  . CYS A 1 342 ? 25.20463  -4.03351  -2.06576  1.000 25.86597  ? 334 CYS A HB3  1 
ATOM   5097 H HG   . CYS A 1 342 ? 25.31894  -1.83693  -3.64536  1.000 25.17213  ? 334 CYS A HG   1 
ATOM   5098 N N    . THR A 1 343 ? 26.86793  -6.36767  -4.67253  1.000 20.53467  ? 335 THR A N    1 
ATOM   5099 C CA   . THR A 1 343 ? 28.27265  -6.67666  -4.91327  1.000 15.99433  ? 335 THR A CA   1 
ATOM   5100 C C    . THR A 1 343 ? 28.86347  -5.54151  -5.73522  1.000 17.51552  ? 335 THR A C    1 
ATOM   5101 O O    . THR A 1 343 ? 29.46361  -4.62149  -5.17373  1.000 21.11918  ? 335 THR A O    1 
ATOM   5102 C CB   . THR A 1 343 ? 28.43580  -8.03309  -5.59508  1.000 23.37781  ? 335 THR A CB   1 
ATOM   5103 O OG1  . THR A 1 343 ? 27.90679  -9.04202  -4.72702  1.000 24.36327  ? 335 THR A OG1  1 
ATOM   5104 C CG2  . THR A 1 343 ? 29.90380  -8.32853  -5.84292  1.000 35.40673  ? 335 THR A CG2  1 
ATOM   5105 H H    . THR A 1 343 ? 26.35964  -6.48267  -5.35665  1.000 24.65862  ? 335 THR A H    1 
ATOM   5106 H HA   . THR A 1 343 ? 28.76166  -6.75387  -4.07912  1.000 19.21022  ? 335 THR A HA   1 
ATOM   5107 H HB   . THR A 1 343 ? 27.97183  -8.03558  -6.44691  1.000 28.07040  ? 335 THR A HB   1 
ATOM   5108 H HG1  . THR A 1 343 ? 28.11094  -9.80437  -5.01466  1.000 29.25295  ? 335 THR A HG1  1 
ATOM   5109 H HG21 . THR A 1 343 ? 30.00354  -9.21201  -6.23076  1.000 42.50510  ? 335 THR A HG21 1 
ATOM   5110 H HG22 . THR A 1 343 ? 30.27569  -7.67290  -6.45345  1.000 42.50510  ? 335 THR A HG22 1 
ATOM   5111 H HG23 . THR A 1 343 ? 30.39480  -8.29441  -5.00706  1.000 42.50510  ? 335 THR A HG23 1 
ATOM   5112 N N    . GLU A 1 344 ? 28.65765  -5.55626  -7.05037  1.000 17.96084  ? 336 GLU A N    1 
ATOM   5113 C CA   . GLU A 1 344 ? 29.12190  -4.48352  -7.91693  1.000 17.84318  ? 336 GLU A CA   1 
ATOM   5114 C C    . GLU A 1 344 ? 28.00258  -3.55140  -8.35776  1.000 21.60447  ? 336 GLU A C    1 
ATOM   5115 O O    . GLU A 1 344 ? 28.27309  -2.54563  -9.01985  1.000 23.53371  ? 336 GLU A O    1 
ATOM   5116 C CB   . GLU A 1 344 ? 29.82809  -5.07277  -9.14043  1.000 25.17328  ? 336 GLU A CB   1 
ATOM   5117 C CG   . GLU A 1 344 ? 31.12313  -5.79180  -8.77467  1.000 35.13147  ? 336 GLU A CG   1 
ATOM   5118 C CD   . GLU A 1 344 ? 31.83324  -6.38596  -9.97561  1.000 36.98349  ? 336 GLU A CD   1 
ATOM   5119 O OE1  . GLU A 1 344 ? 31.33495  -6.22885  -11.10716 1.000 42.62841  ? 336 GLU A OE1  1 
ATOM   5120 O OE2  . GLU A 1 344 ? 32.88987  -7.01643  -9.77687  1.000 51.76559  ? 336 GLU A OE2  1 
ATOM   5121 H H    . GLU A 1 344 ? 28.24596  -6.18629  -7.46652  1.000 21.57003  ? 336 GLU A H    1 
ATOM   5122 H HA   . GLU A 1 344 ? 29.76909  -3.94746  -7.43250  1.000 21.42883  ? 336 GLU A HA   1 
ATOM   5123 H HB2  . GLU A 1 344 ? 29.23839  -5.71255  -9.56920  1.000 30.22496  ? 336 GLU A HB2  1 
ATOM   5124 H HB3  . GLU A 1 344 ? 30.04463  -4.35606  -9.75714  1.000 30.22496  ? 336 GLU A HB3  1 
ATOM   5125 H HG2  . GLU A 1 344 ? 31.72636  -5.15932  -8.35399  1.000 42.17478  ? 336 GLU A HG2  1 
ATOM   5126 H HG3  . GLU A 1 344 ? 30.91931  -6.51457  -8.16070  1.000 42.17478  ? 336 GLU A HG3  1 
ATOM   5127 N N    . GLY A 1 345 ? 26.75970  -3.85777  -8.00670  1.000 17.25206  ? 337 GLY A N    1 
ATOM   5128 C CA   . GLY A 1 345 ? 25.67130  -2.93130  -8.19910  1.000 13.51451  ? 337 GLY A CA   1 
ATOM   5129 C C    . GLY A 1 345 ? 24.87507  -3.09263  -9.47145  1.000 21.15289  ? 337 GLY A C    1 
ATOM   5130 O O    . GLY A 1 345 ? 24.05348  -2.22093  -9.77741  1.000 18.75460  ? 337 GLY A O    1 
ATOM   5131 H H    . GLY A 1 345 ? 26.52602  -4.60554  -7.65197  1.000 20.71950  ? 337 GLY A H    1 
ATOM   5132 H HA2  . GLY A 1 345 ? 25.05428  -3.02707  -7.45679  1.000 16.23443  ? 337 GLY A HA2  1 
ATOM   5133 H HA3  . GLY A 1 345 ? 26.03261  -2.03112  -8.19530  1.000 16.23443  ? 337 GLY A HA3  1 
ATOM   5134 N N    . ASN A 1 346 ? 25.07672  -4.17573  -10.21825 1.000 20.62019  ? 338 ASN A N    1 
ATOM   5135 C CA   . ASN A 1 346 ? 24.39639  -4.31898  -11.50286 1.000 24.37266  ? 338 ASN A CA   1 
ATOM   5136 C C    . ASN A 1 346 ? 22.88132  -4.33583  -11.33587 1.000 17.24925  ? 338 ASN A C    1 
ATOM   5137 O O    . ASN A 1 346 ? 22.15089  -3.77208  -12.16007 1.000 19.88200  ? 338 ASN A O    1 
ATOM   5138 C CB   . ASN A 1 346 ? 24.87084  -5.59313  -12.20094 1.000 25.21471  ? 338 ASN A CB   1 
ATOM   5139 C CG   . ASN A 1 346 ? 26.33456  -5.51416  -12.62187 1.000 36.61999  ? 338 ASN A CG   1 
ATOM   5140 O OD1  . ASN A 1 346 ? 26.65380  -5.12392  -13.74264 1.000 45.83250  ? 338 ASN A OD1  1 
ATOM   5141 N ND2  . ASN A 1 346 ? 27.22615  -5.86663  -11.71135 1.000 43.86991  ? 338 ASN A ND2  1 
ATOM   5142 H H    . ASN A 1 346 ? 25.59290  -4.83094  -10.00883 1.000 24.76125  ? 338 ASN A H    1 
ATOM   5143 H HA   . ASN A 1 346 ? 24.62457  -3.55981  -12.06188 1.000 29.26422  ? 338 ASN A HA   1 
ATOM   5144 H HB2  . ASN A 1 346 ? 24.77166  -6.34339  -11.59416 1.000 30.27468  ? 338 ASN A HB2  1 
ATOM   5145 H HB3  . ASN A 1 346 ? 24.33555  -5.73722  -12.99694 1.000 30.27468  ? 338 ASN A HB3  1 
ATOM   5146 H HD21 . ASN A 1 346 ? 26.96703  -6.12248  -10.93224 1.000 52.66091  ? 338 ASN A HD21 1 
ATOM   5147 H HD22 . ASN A 1 346 ? 28.06518  -5.84004  -11.89822 1.000 52.66091  ? 338 ASN A HD22 1 
ATOM   5148 N N    . ALA A 1 347 ? 22.39475  -4.99801  -10.28962 1.000 15.53212  ? 339 ALA A N    1 
ATOM   5149 C CA   . ALA A 1 347 ? 20.95462  -5.06485  -10.05075 1.000 14.64483  ? 339 ALA A CA   1 
ATOM   5150 C C    . ALA A 1 347 ? 20.39629  -3.70546  -9.64741  1.000 15.93204  ? 339 ALA A C    1 
ATOM   5151 O O    . ALA A 1 347 ? 19.44287  -3.20890  -10.25811 1.000 14.74420  ? 339 ALA A O    1 
ATOM   5152 C CB   . ALA A 1 347 ? 20.65875  -6.12529  -8.98695  1.000 16.81159  ? 339 ALA A CB   1 
ATOM   5153 H H    . ALA A 1 347 ? 22.87150  -5.41406  -9.70721  1.000 18.65556  ? 339 ALA A H    1 
ATOM   5154 H HA   . ALA A 1 347 ? 20.50784  -5.32936  -10.87010 1.000 17.59082  ? 339 ALA A HA   1 
ATOM   5155 H HB1  . ALA A 1 347 ? 19.70375  -6.14552  -8.81826  1.000 20.19094  ? 339 ALA A HB1  1 
ATOM   5156 H HB2  . ALA A 1 347 ? 20.95568  -6.98976  -9.31164  1.000 20.19094  ? 339 ALA A HB2  1 
ATOM   5157 H HB3  . ALA A 1 347 ? 21.13372  -5.89683  -8.17264  1.000 20.19094  ? 339 ALA A HB3  1 
ATOM   5158 N N    . HIS A 1 348 ? 20.98485  -3.07700  -8.62767  1.000 13.76163  ? 340 HIS A N    1 
ATOM   5159 C CA   . HIS A 1 348 ? 20.49139  -1.78569  -8.16524  1.000 10.67423  ? 340 HIS A CA   1 
ATOM   5160 C C    . HIS A 1 348 ? 20.59932  -0.71771  -9.24777  1.000 13.81988  ? 340 HIS A C    1 
ATOM   5161 O O    . HIS A 1 348 ? 19.72052  0.14261   -9.37402  1.000 12.63041  ? 340 HIS A O    1 
ATOM   5162 C CB   . HIS A 1 348 ? 21.27145  -1.35530  -6.91977  1.000 13.76254  ? 340 HIS A CB   1 
ATOM   5163 C CG   . HIS A 1 348 ? 20.68371  -1.83585  -5.63103  1.000 12.31853  ? 340 HIS A CG   1 
ATOM   5164 N ND1  . HIS A 1 348 ? 19.36304  -1.62494  -5.29103  1.000 13.89653  ? 340 HIS A ND1  1 
ATOM   5165 C CD2  . HIS A 1 348 ? 21.24073  -2.49310  -4.58571  1.000 14.28730  ? 340 HIS A CD2  1 
ATOM   5166 C CE1  . HIS A 1 348 ? 19.13423  -2.13149  -4.09475  1.000 12.39526  ? 340 HIS A CE1  1 
ATOM   5167 N NE2  . HIS A 1 348 ? 20.24826  -2.69125  -3.65725  1.000 14.19784  ? 340 HIS A NE2  1 
ATOM   5168 H H    . HIS A 1 348 ? 21.66402  -3.37537  -8.19257  1.000 16.53097  ? 340 HIS A H    1 
ATOM   5169 H HA   . HIS A 1 348 ? 19.55413  -1.87754  -7.93285  1.000 12.82610  ? 340 HIS A HA   1 
ATOM   5170 H HB2  . HIS A 1 348 ? 22.17301  -1.70786  -6.98136  1.000 16.53207  ? 340 HIS A HB2  1 
ATOM   5171 H HB3  . HIS A 1 348 ? 21.29565  -0.38610  -6.88862  1.000 16.53207  ? 340 HIS A HB3  1 
ATOM   5172 H HD2  . HIS A 1 348 ? 22.12845  -2.76002  -4.51081  1.000 17.16178  ? 340 HIS A HD2  1 
ATOM   5173 H HE1  . HIS A 1 348 ? 18.32547  -2.09997  -3.63670  1.000 14.89134  ? 340 HIS A HE1  1 
ATOM   5174 N N    . GLU A 1 349 ? 21.70504  -0.70848  -9.99368  1.000 14.42050  ? 341 GLU A N    1 
ATOM   5175 C CA   . GLU A 1 349 ? 21.86186  0.28945   -11.04348 1.000 16.76318  ? 341 GLU A CA   1 
ATOM   5176 C C    . GLU A 1 349 ? 20.81983  0.12480   -12.13993 1.000 16.02646  ? 341 GLU A C    1 
ATOM   5177 O O    . GLU A 1 349 ? 20.37347  1.11655   -12.72106 1.000 15.24962  ? 341 GLU A O    1 
ATOM   5178 C CB   . GLU A 1 349 ? 23.26774  0.20404   -11.64173 1.000 18.75123  ? 341 GLU A CB   1 
ATOM   5179 C CG   . GLU A 1 349 ? 24.32104  0.96699   -10.84426 1.000 22.04673  ? 341 GLU A CG   1 
ATOM   5180 C CD   . GLU A 1 349 ? 23.97866  2.42813   -10.71973 1.000 18.66681  ? 341 GLU A CD   1 
ATOM   5181 O OE1  . GLU A 1 349 ? 24.25402  3.18752   -11.67995 1.000 20.30338  ? 341 GLU A OE1  1 
ATOM   5182 O OE2  . GLU A 1 349 ? 23.39631  2.81369   -9.67691  1.000 19.50871  ? 341 GLU A OE2  1 
ATOM   5183 H H    . GLU A 1 349 ? 22.36242  -1.25698  -9.91241  1.000 17.32162  ? 341 GLU A H    1 
ATOM   5184 H HA   . GLU A 1 349 ? 21.74979  1.16956   -10.65136 1.000 20.13284  ? 341 GLU A HA   1 
ATOM   5185 H HB2  . GLU A 1 349 ? 23.53719  -0.72724  -11.67361 1.000 22.51850  ? 341 GLU A HB2  1 
ATOM   5186 H HB3  . GLU A 1 349 ? 23.24851  0.57470   -12.53791 1.000 22.51850  ? 341 GLU A HB3  1 
ATOM   5187 H HG2  . GLU A 1 349 ? 24.38041  0.59158   -9.95183  1.000 26.47309  ? 341 GLU A HG2  1 
ATOM   5188 H HG3  . GLU A 1 349 ? 25.17775  0.89273   -11.29308 1.000 26.47309  ? 341 GLU A HG3  1 
ATOM   5189 N N    . THR A 1 350 ? 20.42711  -1.11348  -12.43620 1.000 15.84443  ? 342 THR A N    1 
ATOM   5190 C CA   . THR A 1 350 ? 19.38153  -1.34197  -13.42266 1.000 13.39156  ? 342 THR A CA   1 
ATOM   5191 C C    . THR A 1 350 ? 18.02851  -0.91457  -12.87692 1.000 13.75821  ? 342 THR A C    1 
ATOM   5192 O O    . THR A 1 350 ? 17.25689  -0.24887  -13.57312 1.000 13.82983  ? 342 THR A O    1 
ATOM   5193 C CB   . THR A 1 350 ? 19.36538  -2.81169  -13.83562 1.000 15.48874  ? 342 THR A CB   1 
ATOM   5194 O OG1  . THR A 1 350 ? 20.61843  -3.14938  -14.45176 1.000 15.30155  ? 342 THR A OG1  1 
ATOM   5195 C CG2  . THR A 1 350 ? 18.19265  -3.08995  -14.82294 1.000 16.81738  ? 342 THR A CG2  1 
ATOM   5196 H H    . THR A 1 350 ? 20.74772  -1.82912  -12.08310 1.000 19.03034  ? 342 THR A H    1 
ATOM   5197 H HA   . THR A 1 350 ? 19.56715  -0.81690  -14.21686 1.000 16.08690  ? 342 THR A HA   1 
ATOM   5198 H HB   . THR A 1 350 ? 19.23502  -3.37110  -13.05397 1.000 18.60351  ? 342 THR A HB   1 
ATOM   5199 H HG1  . THR A 1 350 ? 21.23471  -3.12532  -13.88148 1.000 18.37888  ? 342 THR A HG1  1 
ATOM   5200 H HG21 . THR A 1 350 ? 18.27085  -3.98566  -15.18692 1.000 20.19787  ? 342 THR A HG21 1 
ATOM   5201 H HG22 . THR A 1 350 ? 17.34372  -3.01115  -14.36033 1.000 20.19787  ? 342 THR A HG22 1 
ATOM   5202 H HG23 . THR A 1 350 ? 18.21424  -2.45079  -15.55226 1.000 20.19787  ? 342 THR A HG23 1 
ATOM   5203 N N    . ALA A 1 351 ? 17.73054  -1.27776  -11.62495 1.000 13.25332  ? 343 ALA A N    1 
ATOM   5204 C CA   . ALA A 1 351 ? 16.52235  -0.78735  -10.96974 1.000 11.30417  ? 343 ALA A CA   1 
ATOM   5205 C C    . ALA A 1 351 ? 16.46706  0.73721   -11.00022 1.000 16.90516  ? 343 ALA A C    1 
ATOM   5206 O O    . ALA A 1 351 ? 15.43578  1.32933   -11.33527 1.000 10.50518  ? 343 ALA A O    1 
ATOM   5207 C CB   . ALA A 1 351 ? 16.46314  -1.31732  -9.52942  1.000 12.33934  ? 343 ALA A CB   1 
ATOM   5208 H H    . ALA A 1 351 ? 18.20902  -1.80255  -11.13991 1.000 15.92101  ? 343 ALA A H    1 
ATOM   5209 H HA   . ALA A 1 351 ? 15.74271  -1.12106  -11.44058 1.000 13.58202  ? 343 ALA A HA   1 
ATOM   5210 H HB1  . ALA A 1 351 ? 15.67227  -0.96204  -9.09445  1.000 14.82423  ? 343 ALA A HB1  1 
ATOM   5211 H HB2  . ALA A 1 351 ? 16.42180  -2.28620  -9.55087  1.000 14.82423  ? 343 ALA A HB2  1 
ATOM   5212 H HB3  . ALA A 1 351 ? 17.25884  -1.03063  -9.05447  1.000 14.82423  ? 343 ALA A HB3  1 
ATOM   5213 N N    . ARG A 1 352 ? 17.58395  1.38919   -10.65768 1.000 14.51556  ? 344 ARG A N    1 
ATOM   5214 C CA   . ARG A 1 352 ? 17.63395  2.84528   -10.66341 1.000 14.63409  ? 344 ARG A CA   1 
ATOM   5215 C C    . ARG A 1 352 ? 17.43941  3.39531   -12.06847 1.000 11.32466  ? 344 ARG A C    1 
ATOM   5216 O O    . ARG A 1 352 ? 16.72667  4.38182   -12.25755 1.000 13.94142  ? 344 ARG A O    1 
ATOM   5217 C CB   . ARG A 1 352 ? 18.96636  3.32630   -10.08545 1.000 15.88048  ? 344 ARG A CB   1 
ATOM   5218 C CG   . ARG A 1 352 ? 19.05105  4.83312   -9.89845  1.000 16.63549  ? 344 ARG A CG   1 
ATOM   5219 C CD   . ARG A 1 352 ? 20.36880  5.22246   -9.24267  1.000 17.06850  ? 344 ARG A CD   1 
ATOM   5220 N NE   . ARG A 1 352 ? 21.51748  5.00942   -10.12274 1.000 18.65793  ? 344 ARG A NE   1 
ATOM   5221 C CZ   . ARG A 1 352 ? 21.81972  5.78142   -11.16409 1.000 19.77546  ? 344 ARG A CZ   1 
ATOM   5222 N NH1  . ARG A 1 352 ? 21.05665  6.80579   -11.46977 1.000 17.42089  ? 344 ARG A NH1  1 
ATOM   5223 N NH2  . ARG A 1 352 ? 22.88665  5.52744   -11.90524 1.000 22.09177  ? 344 ARG A NH2  1 
ATOM   5224 H H    . ARG A 1 352 ? 18.31892  1.01093   -10.42035 1.000 17.43570  ? 344 ARG A H    1 
ATOM   5225 H HA   . ARG A 1 352 ? 16.91935  3.18448   -10.10199 1.000 17.57793  ? 344 ARG A HA   1 
ATOM   5226 H HB2  . ARG A 1 352 ? 19.09588  2.91338   -9.21733  1.000 19.07360  ? 344 ARG A HB2  1 
ATOM   5227 H HB3  . ARG A 1 352 ? 19.67967  3.06306   -10.68777 1.000 19.07360  ? 344 ARG A HB3  1 
ATOM   5228 H HG2  . ARG A 1 352 ? 18.99599  5.27054   -10.76247 1.000 19.97961  ? 344 ARG A HG2  1 
ATOM   5229 H HG3  . ARG A 1 352 ? 18.32412  5.13042   -9.32916  1.000 19.97961  ? 344 ARG A HG3  1 
ATOM   5230 H HD2  . ARG A 1 352 ? 20.34037  6.16316   -9.00778  1.000 20.49922  ? 344 ARG A HD2  1 
ATOM   5231 H HD3  . ARG A 1 352 ? 20.49716  4.68516   -8.44535  1.000 20.49922  ? 344 ARG A HD3  1 
ATOM   5232 H HE   . ARG A 1 352 ? 22.03196  4.34069   -9.95626  1.000 22.40654  ? 344 ARG A HE   1 
ATOM   5233 H HH11 . ARG A 1 352 ? 20.35972  6.97914   -10.99665 1.000 20.92209  ? 344 ARG A HH11 1 
ATOM   5234 H HH12 . ARG A 1 352 ? 21.25392  7.30317   -12.14304 1.000 20.92209  ? 344 ARG A HH12 1 
ATOM   5235 H HH21 . ARG A 1 352 ? 23.39239  4.85815   -11.71583 1.000 26.52714  ? 344 ARG A HH21 1 
ATOM   5236 H HH22 . ARG A 1 352 ? 23.07410  6.03172   -12.57618 1.000 26.52714  ? 344 ARG A HH22 1 
ATOM   5237 N N    . MET A 1 353 ? 18.03407  2.74600   -13.06656 1.000 16.18083  ? 345 MET A N    1 
ATOM   5238 C CA   . MET A 1 353 ? 17.93034  3.23796   -14.43611 1.000 14.11788  ? 345 MET A CA   1 
ATOM   5239 C C    . MET A 1 353 ? 16.47235  3.27215   -14.88533 1.000 14.87038  ? 345 MET A C    1 
ATOM   5240 O O    . MET A 1 353 ? 15.99897  4.27296   -15.43819 1.000 15.44427  ? 345 MET A O    1 
ATOM   5241 C CB   . MET A 1 353 ? 18.77889  2.35908   -15.36013 1.000 18.00738  ? 345 MET A CB   1 
ATOM   5242 C CG   . MET A 1 353 ? 18.75753  2.77664   -16.81896 1.000 21.15432  ? 345 MET A CG   1 
ATOM   5243 S SD   . MET A 1 353 ? 19.82074  1.75965   -17.85924 1.000 21.89236  ? 345 MET A SD   1 
ATOM   5244 C CE   . MET A 1 353 ? 21.39012  1.89533   -17.00601 1.000 25.23353  ? 345 MET A CE   1 
ATOM   5245 H H    . MET A 1 353 ? 18.49784  2.02711   -12.97875 1.000 19.43402  ? 345 MET A H    1 
ATOM   5246 H HA   . MET A 1 353 ? 18.28585  4.13924   -14.48313 1.000 16.95848  ? 345 MET A HA   1 
ATOM   5247 H HB2  . MET A 1 353 ? 19.70029  2.39341   -15.05890 1.000 21.62588  ? 345 MET A HB2  1 
ATOM   5248 H HB3  . MET A 1 353 ? 18.44745  1.44879   -15.31093 1.000 21.62588  ? 345 MET A HB3  1 
ATOM   5249 H HG2  . MET A 1 353 ? 17.85066  2.70149   -17.15486 1.000 25.40221  ? 345 MET A HG2  1 
ATOM   5250 H HG3  . MET A 1 353 ? 19.06192  3.69504   -16.88820 1.000 25.40221  ? 345 MET A HG3  1 
ATOM   5251 H HE1  . MET A 1 353 ? 22.09417  1.56420   -17.58529 1.000 30.29725  ? 345 MET A HE1  1 
ATOM   5252 H HE2  . MET A 1 353 ? 21.55166  2.82665   -16.78817 1.000 30.29725  ? 345 MET A HE2  1 
ATOM   5253 H HE3  . MET A 1 353 ? 21.35448  1.36691   -16.19336 1.000 30.29725  ? 345 MET A HE3  1 
ATOM   5254 N N    . TYR A 1 354 ? 15.73147  2.18940   -14.63119 1.000 16.26011  ? 346 TYR A N    1 
ATOM   5255 C CA   . TYR A 1 354 ? 14.33449  2.15442   -15.05313 1.000 15.04514  ? 346 TYR A CA   1 
ATOM   5256 C C    . TYR A 1 354 ? 13.49031  3.14907   -14.27270 1.000 13.58612  ? 346 TYR A C    1 
ATOM   5257 O O    . TYR A 1 354 ? 12.66640  3.86577   -14.85528 1.000 12.50262  ? 346 TYR A O    1 
ATOM   5258 C CB   . TYR A 1 354 ? 13.77940  0.73384   -14.90909 1.000 12.25762  ? 346 TYR A CB   1 
ATOM   5259 C CG   . TYR A 1 354 ? 14.09825  -0.09240  -16.12664 1.000 12.69941  ? 346 TYR A CG   1 
ATOM   5260 C CD1  . TYR A 1 354 ? 15.31551  -0.73357  -16.25336 1.000 14.43947  ? 346 TYR A CD1  1 
ATOM   5261 C CD2  . TYR A 1 354 ? 13.19694  -0.18289  -17.17913 1.000 13.23249  ? 346 TYR A CD2  1 
ATOM   5262 C CE1  . TYR A 1 354 ? 15.61830  -1.47731  -17.39166 1.000 15.53296  ? 346 TYR A CE1  1 
ATOM   5263 C CE2  . TYR A 1 354 ? 13.49394  -0.90326  -18.31686 1.000 11.99834  ? 346 TYR A CE2  1 
ATOM   5264 C CZ   . TYR A 1 354 ? 14.70672  -1.54996  -18.42075 1.000 18.07516  ? 346 TYR A CZ   1 
ATOM   5265 O OH   . TYR A 1 354 ? 15.00752  -2.26818  -19.55762 1.000 14.94571  ? 346 TYR A OH   1 
ATOM   5266 H H    . TYR A 1 354 ? 16.00800  1.48243   -14.22706 1.000 19.52916  ? 346 TYR A H    1 
ATOM   5267 H HA   . TYR A 1 354 ? 14.28545  2.40079   -15.99004 1.000 18.07119  ? 346 TYR A HA   1 
ATOM   5268 H HB2  . TYR A 1 354 ? 14.17867  0.30807   -14.13436 1.000 14.72616  ? 346 TYR A HB2  1 
ATOM   5269 H HB3  . TYR A 1 354 ? 12.81562  0.77253   -14.80651 1.000 14.72616  ? 346 TYR A HB3  1 
ATOM   5270 H HD1  . TYR A 1 354 ? 15.94170  -0.66768  -15.56893 1.000 17.34438  ? 346 TYR A HD1  1 
ATOM   5271 H HD2  . TYR A 1 354 ? 12.37678  0.25092   -17.11545 1.000 15.89601  ? 346 TYR A HD2  1 
ATOM   5272 H HE1  . TYR A 1 354 ? 16.43224  -1.92257  -17.45609 1.000 18.65658  ? 346 TYR A HE1  1 
ATOM   5273 H HE2  . TYR A 1 354 ? 12.87793  -0.95259  -19.01184 1.000 14.41502  ? 346 TYR A HE2  1 
ATOM   5274 H HH   . TYR A 1 354 ? 15.75230  -2.64657  -19.46974 1.000 17.95187  ? 346 TYR A HH   1 
ATOM   5275 N N    . LEU A 1 355 ? 13.68259  3.22288   -12.95456 1.000 10.94852  ? 347 LEU A N    1 
ATOM   5276 C CA   . LEU A 1 355 ? 12.85946  4.12245   -12.15280 1.000 12.78274  ? 347 LEU A CA   1 
ATOM   5277 C C    . LEU A 1 355 ? 13.18940  5.58542   -12.43152 1.000 11.84079  ? 347 LEU A C    1 
ATOM   5278 O O    . LEU A 1 355 ? 12.28962  6.43394   -12.47232 1.000 15.56749  ? 347 LEU A O    1 
ATOM   5279 C CB   . LEU A 1 355 ? 13.03926  3.80023   -10.66723 1.000 13.74954  ? 347 LEU A CB   1 
ATOM   5280 C CG   . LEU A 1 355 ? 12.46424  2.46608   -10.21987 1.000 13.06051  ? 347 LEU A CG   1 
ATOM   5281 C CD1  . LEU A 1 355 ? 12.96103  2.08603   -8.82664  1.000 13.67586  ? 347 LEU A CD1  1 
ATOM   5282 C CD2  . LEU A 1 355 ? 10.93392  2.50959   -10.25363 1.000 13.58358  ? 347 LEU A CD2  1 
ATOM   5283 H H    . LEU A 1 355 ? 14.26806  2.77396   -12.51264 1.000 13.15525  ? 347 LEU A H    1 
ATOM   5284 H HA   . LEU A 1 355 ? 11.92778  3.98364   -12.38432 1.000 15.35631  ? 347 LEU A HA   1 
ATOM   5285 H HB2  . LEU A 1 355 ? 13.98893  3.78814   -10.47002 1.000 16.51647  ? 347 LEU A HB2  1 
ATOM   5286 H HB3  . LEU A 1 355 ? 12.60163  4.49369   -10.14907 1.000 16.51647  ? 347 LEU A HB3  1 
ATOM   5287 H HG   . LEU A 1 355 ? 12.76601  1.77748   -10.83279 1.000 15.68963  ? 347 LEU A HG   1 
ATOM   5288 H HD11 . LEU A 1 355 ? 12.57651  1.23136   -8.57650  1.000 16.42806  ? 347 LEU A HD11 1 
ATOM   5289 H HD12 . LEU A 1 355 ? 13.92872  2.02123   -8.84321  1.000 16.42806  ? 347 LEU A HD12 1 
ATOM   5290 H HD13 . LEU A 1 355 ? 12.68605  2.76975   -8.19592  1.000 16.42806  ? 347 LEU A HD13 1 
ATOM   5291 H HD21 . LEU A 1 355 ? 10.58665  1.66641   -9.92295  1.000 16.31732  ? 347 LEU A HD21 1 
ATOM   5292 H HD22 . LEU A 1 355 ? 10.62620  3.23746   -9.69113  1.000 16.31732  ? 347 LEU A HD22 1 
ATOM   5293 H HD23 . LEU A 1 355 ? 10.64212  2.65181   -11.16770 1.000 16.31732  ? 347 LEU A HD23 1 
ATOM   5294 N N    . LYS A 1 356 ? 14.47463  5.90044   -12.59601 1.000 15.58171  ? 348 LYS A N    1 
ATOM   5295 C CA   . LYS A 1 356 ? 14.85949  7.25277   -12.96749 1.000 16.71542  ? 348 LYS A CA   1 
ATOM   5296 C C    . LYS A 1 356 ? 14.23937  7.63251   -14.30162 1.000 20.02196  ? 348 LYS A C    1 
ATOM   5297 O O    . LYS A 1 356 ? 13.73475  8.74975   -14.46108 1.000 19.05506  ? 348 LYS A O    1 
ATOM   5298 C CB   . LYS A 1 356 ? 16.38298  7.35803   -13.01875 1.000 19.91453  ? 348 LYS A CB   1 
ATOM   5299 C CG   . LYS A 1 356 ? 16.91085  8.74955   -13.41338 1.000 22.59186  ? 348 LYS A CG   1 
ATOM   5300 C CD   . LYS A 1 356 ? 18.42731  8.74776   -13.48522 1.000 23.47055  ? 348 LYS A CD   1 
ATOM   5301 C CE   . LYS A 1 356 ? 18.94875  10.07693  -14.03455 1.000 30.88943  ? 348 LYS A CE   1 
ATOM   5302 N NZ   . LYS A 1 356 ? 20.42280  10.06144  -14.19721 1.000 34.55470  ? 348 LYS A NZ   1 
ATOM   5303 H H    . LYS A 1 356 ? 15.13207  5.35456   -12.49907 1.000 18.71507  ? 348 LYS A H    1 
ATOM   5304 H HA   . LYS A 1 356 ? 14.54338  7.88024   -12.29872 1.000 20.07553  ? 348 LYS A HA   1 
ATOM   5305 H HB2  . LYS A 1 356 ? 16.73735  7.14788   -12.14060 1.000 23.91445  ? 348 LYS A HB2  1 
ATOM   5306 H HB3  . LYS A 1 356 ? 16.71526  6.72210   -13.67149 1.000 23.91445  ? 348 LYS A HB3  1 
ATOM   5307 H HG2  . LYS A 1 356 ? 16.56132  8.99395   -14.28459 1.000 27.12726  ? 348 LYS A HG2  1 
ATOM   5308 H HG3  . LYS A 1 356 ? 16.63448  9.40132   -12.75028 1.000 27.12726  ? 348 LYS A HG3  1 
ATOM   5309 H HD2  . LYS A 1 356 ? 18.79328  8.61767   -12.59638 1.000 28.18169  ? 348 LYS A HD2  1 
ATOM   5310 H HD3  . LYS A 1 356 ? 18.72264  8.03503   -14.07318 1.000 28.18169  ? 348 LYS A HD3  1 
ATOM   5311 H HE2  . LYS A 1 356 ? 18.54854  10.24426  -14.90216 1.000 37.08434  ? 348 LYS A HE2  1 
ATOM   5312 H HE3  . LYS A 1 356 ? 18.71788  10.79059  -13.41951 1.000 37.08434  ? 348 LYS A HE3  1 
ATOM   5313 H HZ1  . LYS A 1 356 ? 20.69155  10.80389  -14.60786 1.000 41.48266  ? 348 LYS A HZ1  1 
ATOM   5314 H HZ2  . LYS A 1 356 ? 20.81648  10.01340  -13.40045 1.000 41.48266  ? 348 LYS A HZ2  1 
ATOM   5315 H HZ3  . LYS A 1 356 ? 20.66802  9.35750   -14.68345 1.000 41.48266  ? 348 LYS A HZ3  1 
ATOM   5316 N N    . ALA A 1 357 ? 14.23063  6.69892   -15.26136 1.000 18.65858  ? 349 ALA A N    1 
ATOM   5317 C CA   . ALA A 1 357 ? 13.63779  6.98860   -16.56212 1.000 18.00015  ? 349 ALA A CA   1 
ATOM   5318 C C    . ALA A 1 357 ? 12.15410  7.29693   -16.43244 1.000 17.89349  ? 349 ALA A C    1 
ATOM   5319 O O    . ALA A 1 357 ? 11.60135  8.06420   -17.22597 1.000 23.50920  ? 349 ALA A O    1 
ATOM   5320 C CB   . ALA A 1 357 ? 13.85948  5.81561   -17.51603 1.000 20.25575  ? 349 ALA A CB   1 
ATOM   5321 H H    . ALA A 1 357 ? 14.55599  5.90677   -15.18246 1.000 22.40732  ? 349 ALA A H    1 
ATOM   5322 H HA   . ALA A 1 357 ? 14.07657  7.76494   -16.94378 1.000 21.61720  ? 349 ALA A HA   1 
ATOM   5323 H HB1  . ALA A 1 357 ? 13.48735  6.03928   -18.38344 1.000 24.32392  ? 349 ALA A HB1  1 
ATOM   5324 H HB2  . ALA A 1 357 ? 14.81182  5.65031   -17.59733 1.000 24.32392  ? 349 ALA A HB2  1 
ATOM   5325 H HB3  . ALA A 1 357 ? 13.41671  5.02998   -17.15876 1.000 24.32392  ? 349 ALA A HB3  1 
ATOM   5326 N N    . ALA A 1 358 ? 11.49662  6.72355   -15.43470 1.000 16.87490  ? 350 ALA A N    1 
ATOM   5327 C CA   . ALA A 1 358 ? 10.09570  7.00594   -15.15424 1.000 17.57758  ? 350 ALA A CA   1 
ATOM   5328 C C    . ALA A 1 358 ? 9.91728   8.22352   -14.25884 1.000 20.89704  ? 350 ALA A C    1 
ATOM   5329 O O    . ALA A 1 358 ? 8.78429   8.55199   -13.90129 1.000 20.11659  ? 350 ALA A O    1 
ATOM   5330 C CB   . ALA A 1 358 ? 9.43435   5.78166   -14.51417 1.000 22.03686  ? 350 ALA A CB   1 
ATOM   5331 H H    . ALA A 1 358 ? 11.84742  6.15457   -14.89359 1.000 20.26690  ? 350 ALA A H    1 
ATOM   5332 H HA   . ALA A 1 358 ? 9.63361   7.18325   -15.98847 1.000 21.11012  ? 350 ALA A HA   1 
ATOM   5333 H HB1  . ALA A 1 358 ? 8.50317   5.98423   -14.33318 1.000 26.46126  ? 350 ALA A HB1  1 
ATOM   5334 H HB2  . ALA A 1 358 ? 9.49681   5.03242   -15.12706 1.000 26.46126  ? 350 ALA A HB2  1 
ATOM   5335 H HB3  . ALA A 1 358 ? 9.89401   5.57107   -13.68636 1.000 26.46126  ? 350 ALA A HB3  1 
ATOM   5336 N N    . GLY A 1 359 ? 10.99973  8.90006   -13.89585 1.000 19.05113  ? 351 GLY A N    1 
ATOM   5337 C CA   . GLY A 1 359 ? 10.91475  10.15399  -13.17515 1.000 24.13010  ? 351 GLY A CA   1 
ATOM   5338 C C    . GLY A 1 359 ? 10.97190  10.04204  -11.67130 1.000 23.16579  ? 351 GLY A C    1 
ATOM   5339 O O    . GLY A 1 359 ? 10.75437  11.04383  -10.97807 1.000 19.95204  ? 351 GLY A O    1 
ATOM   5340 H H    . GLY A 1 359 ? 11.80516  8.64685   -14.05946 1.000 22.87838  ? 351 GLY A H    1 
ATOM   5341 H HA2  . GLY A 1 359 ? 11.65015  10.72105  -13.45536 1.000 28.97314  ? 351 GLY A HA2  1 
ATOM   5342 H HA3  . GLY A 1 359 ? 10.07735  10.58589  -13.40565 1.000 28.97314  ? 351 GLY A HA3  1 
ATOM   5343 N N    . ALA A 1 360 ? 11.27018  8.87079   -11.14276 1.000 16.08090  ? 352 ALA A N    1 
ATOM   5344 C CA   . ALA A 1 360 ? 11.27374  8.69166   -9.70420  1.000 14.27712  ? 352 ALA A CA   1 
ATOM   5345 C C    . ALA A 1 360 ? 12.60257  9.13335   -9.09609  1.000 12.88399  ? 352 ALA A C    1 
ATOM   5346 O O    . ALA A 1 360 ? 13.63767  9.18541   -9.76758  1.000 18.12230  ? 352 ALA A O    1 
ATOM   5347 C CB   . ALA A 1 360 ? 11.00217  7.22980   -9.35869  1.000 15.92613  ? 352 ALA A CB   1 
ATOM   5348 H H    . ALA A 1 360 ? 11.47317  8.16718   -11.59368 1.000 19.31411  ? 352 ALA A H    1 
ATOM   5349 H HA   . ALA A 1 360 ? 10.57553  9.23970   -9.31298  1.000 17.14957  ? 352 ALA A HA   1 
ATOM   5350 H HB1  . ALA A 1 360 ? 10.99908  7.12861   -8.39399  1.000 19.12838  ? 352 ALA A HB1  1 
ATOM   5351 H HB2  . ALA A 1 360 ? 10.13919  6.97477   -9.72080  1.000 19.12838  ? 352 ALA A HB2  1 
ATOM   5352 H HB3  . ALA A 1 360 ? 11.69970  6.67872   -9.74685  1.000 19.12838  ? 352 ALA A HB3  1 
ATOM   5353 N N    . ASN A 1 361 ? 12.55536  9.41280   -7.78829  1.000 19.70515  ? 353 ASN A N    1 
ATOM   5354 C CA   . ASN A 1 361 ? 13.72829  9.67214   -6.96062  1.000 15.69837  ? 353 ASN A CA   1 
ATOM   5355 C C    . ASN A 1 361 ? 14.04969  8.39726   -6.19535  1.000 11.57366  ? 353 ASN A C    1 
ATOM   5356 O O    . ASN A 1 361 ? 13.24753  7.96283   -5.36595  1.000 17.38675  ? 353 ASN A O    1 
ATOM   5357 C CB   . ASN A 1 361 ? 13.45023  10.82221  -5.99776  1.000 17.22157  ? 353 ASN A CB   1 
ATOM   5358 C CG   . ASN A 1 361 ? 13.26532  12.13578  -6.72106  1.000 25.12433  ? 353 ASN A CG   1 
ATOM   5359 O OD1  . ASN A 1 361 ? 13.95298  12.40611  -7.69424  1.000 21.62482  ? 353 ASN A OD1  1 
ATOM   5360 N ND2  . ASN A 1 361 ? 12.32697  12.95059  -6.25911  1.000 26.54983  ? 353 ASN A ND2  1 
ATOM   5361 H H    . ASN A 1 361 ? 11.82099  9.45866   -7.34310  1.000 23.66320  ? 353 ASN A H    1 
ATOM   5362 H HA   . ASN A 1 361 ? 14.49023  9.91177   -7.51101  1.000 18.85506  ? 353 ASN A HA   1 
ATOM   5363 H HB2  . ASN A 1 361 ? 12.63875  10.63305  -5.50114  1.000 20.68290  ? 353 ASN A HB2  1 
ATOM   5364 H HB3  . ASN A 1 361 ? 14.19855  10.91513  -5.38761  1.000 20.68290  ? 353 ASN A HB3  1 
ATOM   5365 H HD21 . ASN A 1 361 ? 12.18901  13.70832  -6.64175  1.000 31.87682  ? 353 ASN A HD21 1 
ATOM   5366 H HD22 . ASN A 1 361 ? 11.85626  12.72139  -5.57684  1.000 31.87682  ? 353 ASN A HD22 1 
ATOM   5367 N N    . VAL A 1 362 ? 15.20907  7.80353   -6.47612  1.000 13.63161  ? 354 VAL A N    1 
ATOM   5368 C CA   . VAL A 1 362 ? 15.48884  6.41327   -6.12135  1.000 14.58599  ? 354 VAL A CA   1 
ATOM   5369 C C    . VAL A 1 362 ? 16.47612  6.33335   -4.96965  1.000 14.56648  ? 354 VAL A C    1 
ATOM   5370 O O    . VAL A 1 362 ? 17.50835  7.01085   -4.96807  1.000 17.59334  ? 354 VAL A O    1 
ATOM   5371 C CB   . VAL A 1 362 ? 16.03246  5.63465   -7.33546  1.000 16.25343  ? 354 VAL A CB   1 
ATOM   5372 C CG1  . VAL A 1 362 ? 16.36978  4.18182   -6.97926  1.000 15.13868  ? 354 VAL A CG1  1 
ATOM   5373 C CG2  . VAL A 1 362 ? 15.02795  5.69292   -8.49576  1.000 17.47118  ? 354 VAL A CG2  1 
ATOM   5374 H H    . VAL A 1 362 ? 15.86089  8.19367   -6.87926  1.000 16.37495  ? 354 VAL A H    1 
ATOM   5375 H HA   . VAL A 1 362 ? 14.65881  6.01551   -5.81518  1.000 17.52022  ? 354 VAL A HA   1 
ATOM   5376 H HB   . VAL A 1 362 ? 16.85968  6.05489   -7.61833  1.000 19.52114  ? 354 VAL A HB   1 
ATOM   5377 H HG11 . VAL A 1 362 ? 16.54390  3.68864   -7.79617  1.000 18.18344  ? 354 VAL A HG11 1 
ATOM   5378 H HG12 . VAL A 1 362 ? 17.15642  4.17026   -6.41185  1.000 18.18344  ? 354 VAL A HG12 1 
ATOM   5379 H HG13 . VAL A 1 362 ? 15.61742  3.78895   -6.50968  1.000 18.18344  ? 354 VAL A HG13 1 
ATOM   5380 H HG21 . VAL A 1 362 ? 15.35982  5.15059   -9.22831  1.000 20.98244  ? 354 VAL A HG21 1 
ATOM   5381 H HG22 . VAL A 1 362 ? 14.17328  5.34998   -8.19107  1.000 20.98244  ? 354 VAL A HG22 1 
ATOM   5382 H HG23 . VAL A 1 362 ? 14.93109  6.61414   -8.78365  1.000 20.98244  ? 354 VAL A HG23 1 
ATOM   5383 N N    . ILE A 1 363 ? 16.17721  5.45866   -4.01830  1.000 11.60935  ? 355 ILE A N    1 
ATOM   5384 C CA   . ILE A 1 363 ? 17.09037  5.07291   -2.95059  1.000 15.45009  ? 355 ILE A CA   1 
ATOM   5385 C C    . ILE A 1 363 ? 17.36444  3.58187   -3.09406  1.000 15.13810  ? 355 ILE A C    1 
ATOM   5386 O O    . ILE A 1 363 ? 16.42448  2.77977   -3.15201  1.000 14.83164  ? 355 ILE A O    1 
ATOM   5387 C CB   . ILE A 1 363 ? 16.49996  5.38272   -1.56181  1.000 12.14308  ? 355 ILE A CB   1 
ATOM   5388 C CG1  . ILE A 1 363 ? 16.08170  6.85535   -1.45357  1.000 16.48827  ? 355 ILE A CG1  1 
ATOM   5389 C CG2  . ILE A 1 363 ? 17.50529  4.98714   -0.46834  1.000 17.15731  ? 355 ILE A CG2  1 
ATOM   5390 C CD1  . ILE A 1 363 ? 17.22786  7.82103   -1.50632  1.000 18.51581  ? 355 ILE A CD1  1 
ATOM   5391 H H    . ILE A 1 363 ? 15.41807  5.05769   -3.96804  1.000 13.94824  ? 355 ILE A H    1 
ATOM   5392 H HA   . ILE A 1 363 ? 17.92543  5.55775   -3.04292  1.000 18.55713  ? 355 ILE A HA   1 
ATOM   5393 H HB   . ILE A 1 363 ? 15.69528  4.85514   -1.43915  1.000 14.58871  ? 355 ILE A HB   1 
ATOM   5394 H HG12 . ILE A 1 363 ? 15.48595  7.06422   -2.19001  1.000 19.80294  ? 355 ILE A HG12 1 
ATOM   5395 H HG13 . ILE A 1 363 ? 15.62369  6.98711   -0.60872  1.000 19.80294  ? 355 ILE A HG13 1 
ATOM   5396 H HG21 . ILE A 1 363 ? 17.15777  5.26203   0.39455   1.000 20.60579  ? 355 ILE A HG21 1 
ATOM   5397 H HG22 . ILE A 1 363 ? 17.62720  4.02497   -0.48456  1.000 20.60579  ? 355 ILE A HG22 1 
ATOM   5398 H HG23 . ILE A 1 363 ? 18.35051  5.43062   -0.64105  1.000 20.60579  ? 355 ILE A HG23 1 
ATOM   5399 H HD11 . ILE A 1 363 ? 16.87960  8.72606   -1.48334  1.000 22.23599  ? 355 ILE A HD11 1 
ATOM   5400 H HD12 . ILE A 1 363 ? 17.80442  7.66894   -0.74124  1.000 22.23599  ? 355 ILE A HD12 1 
ATOM   5401 H HD13 . ILE A 1 363 ? 17.72364  7.67815   -2.32771  1.000 22.23599  ? 355 ILE A HD13 1 
ATOM   5402 N N    . ASN A 1 364 ? 18.64203  3.20355   -3.13232  1.000 9.93625   ? 356 ASN A N    1 
ATOM   5403 C CA   . ASN A 1 364 ? 19.03802  1.81328   -3.33713  1.000 10.42079  ? 356 ASN A CA   1 
ATOM   5404 C C    . ASN A 1 364 ? 19.55203  1.24075   -2.02020  1.000 15.43302  ? 356 ASN A C    1 
ATOM   5405 O O    . ASN A 1 364 ? 20.64577  1.58876   -1.56692  1.000 14.00395  ? 356 ASN A O    1 
ATOM   5406 C CB   . ASN A 1 364 ? 20.08732  1.70204   -4.43846  1.000 12.05173  ? 356 ASN A CB   1 
ATOM   5407 C CG   . ASN A 1 364 ? 19.52364  2.03296   -5.80658  1.000 11.88978  ? 356 ASN A CG   1 
ATOM   5408 O OD1  . ASN A 1 364 ? 19.65310  3.14981   -6.29822  1.000 14.52132  ? 356 ASN A OD1  1 
ATOM   5409 N ND2  . ASN A 1 364 ? 18.87948  1.04377   -6.43182  1.000 15.20268  ? 356 ASN A ND2  1 
ATOM   5410 H H    . ASN A 1 364 ? 19.30528  3.74326   -3.04062  1.000 11.94052  ? 356 ASN A H    1 
ATOM   5411 H HA   . ASN A 1 364 ? 18.25876  1.29908   -3.60029  1.000 12.52197  ? 356 ASN A HA   1 
ATOM   5412 H HB2  . ASN A 1 364 ? 20.81038  2.32123   -4.25216  1.000 14.47910  ? 356 ASN A HB2  1 
ATOM   5413 H HB3  . ASN A 1 364 ? 20.42660  0.79366   -4.46352  1.000 14.47910  ? 356 ASN A HB3  1 
ATOM   5414 H HD21 . ASN A 1 364 ? 18.53976  1.17659   -7.21063  1.000 18.26023  ? 356 ASN A HD21 1 
ATOM   5415 H HD22 . ASN A 1 364 ? 18.80447  0.27411   -6.05553  1.000 18.26023  ? 356 ASN A HD22 1 
ATOM   5416 N N    . ILE A 1 365 ? 18.77632  0.33756   -1.42905  1.000 9.27946   ? 357 ILE A N    1 
ATOM   5417 C CA   . ILE A 1 365 ? 19.06431  -0.22632  -0.11560  1.000 10.61139  ? 357 ILE A CA   1 
ATOM   5418 C C    . ILE A 1 365 ? 19.33600  -1.71694  -0.25453  1.000 14.90751  ? 357 ILE A C    1 
ATOM   5419 O O    . ILE A 1 365 ? 18.60938  -2.43006  -0.95878  1.000 13.53959  ? 357 ILE A O    1 
ATOM   5420 C CB   . ILE A 1 365 ? 17.90547  0.01764   0.87125   1.000 12.00310  ? 357 ILE A CB   1 
ATOM   5421 C CG1  . ILE A 1 365 ? 17.75782  1.50500   1.18538   1.000 12.83943  ? 357 ILE A CG1  1 
ATOM   5422 C CG2  . ILE A 1 365 ? 18.15334  -0.73839  2.17157   1.000 14.65709  ? 357 ILE A CG2  1 
ATOM   5423 C CD1  . ILE A 1 365 ? 16.38927  1.87422   1.76634   1.000 12.25205  ? 357 ILE A CD1  1 
ATOM   5424 H H    . ILE A 1 365 ? 18.05562  0.02691   -1.78075  1.000 11.15237  ? 357 ILE A H    1 
ATOM   5425 H HA   . ILE A 1 365 ? 19.86491  0.19751   0.23126   1.000 12.75069  ? 357 ILE A HA   1 
ATOM   5426 H HB   . ILE A 1 365 ? 17.09131  -0.30103  0.45114   1.000 14.42075  ? 357 ILE A HB   1 
ATOM   5427 H HG12 . ILE A 1 365 ? 18.43359  1.75622   1.83431   1.000 15.42434  ? 357 ILE A HG12 1 
ATOM   5428 H HG13 . ILE A 1 365 ? 17.87943  2.01114   0.36689   1.000 15.42434  ? 357 ILE A HG13 1 
ATOM   5429 H HG21 . ILE A 1 365 ? 17.49392  -0.46312  2.82754   1.000 17.60554  ? 357 ILE A HG21 1 
ATOM   5430 H HG22 . ILE A 1 365 ? 18.07498  -1.69044  2.00318   1.000 17.60554  ? 357 ILE A HG22 1 
ATOM   5431 H HG23 . ILE A 1 365 ? 19.04515  -0.53147  2.49211   1.000 17.60554  ? 357 ILE A HG23 1 
ATOM   5432 H HD11 . ILE A 1 365 ? 16.34726  2.83549   1.88917   1.000 14.71949  ? 357 ILE A HD11 1 
ATOM   5433 H HD12 . ILE A 1 365 ? 15.69702  1.58898   1.14963   1.000 14.71949  ? 357 ILE A HD12 1 
ATOM   5434 H HD13 . ILE A 1 365 ? 16.27717  1.42652   2.61951   1.000 14.71949  ? 357 ILE A HD13 1 
ATOM   5435 N N    . SER A 1 366 ? 20.37039  -2.19452  0.44190   1.000 11.66109  ? 358 SER A N    1 
ATOM   5436 C CA   . SER A 1 366 ? 20.70525  -3.61016  0.45743   1.000 11.45869  ? 358 SER A CA   1 
ATOM   5437 C C    . SER A 1 366 ? 20.86240  -4.10908  1.88331   1.000 12.97483  ? 358 SER A C    1 
ATOM   5438 O O    . SER A 1 366 ? 21.30174  -3.37457  2.76979   1.000 12.75265  ? 358 SER A O    1 
ATOM   5439 C CB   . SER A 1 366 ? 22.00999  -3.87921  -0.31222  1.000 11.98380  ? 358 SER A CB   1 
ATOM   5440 O OG   . SER A 1 366 ? 21.94979  -3.34201  -1.61989  1.000 14.25305  ? 358 SER A OG   1 
ATOM   5441 H H    . SER A 1 366 ? 20.89629  -1.70778  0.91742   1.000 14.01033  ? 358 SER A H    1 
ATOM   5442 H HA   . SER A 1 366 ? 19.98013  -4.10622  0.04631   1.000 13.76745  ? 358 SER A HA   1 
ATOM   5443 H HB2  . SER A 1 366 ? 22.74726  -3.46630  0.16407   1.000 14.39759  ? 358 SER A HB2  1 
ATOM   5444 H HB3  . SER A 1 366 ? 22.14853  -4.83742  -0.37163  1.000 14.39759  ? 358 SER A HB3  1 
ATOM   5445 H HG   . SER A 1 366 ? 21.39425  -3.77094  -2.08140  1.000 17.12068  ? 358 SER A HG   1 
ATOM   5446 N N    . TRP A 1 367 ? 20.48926  -5.37122  2.09771   1.000 11.56102  ? 359 TRP A N    1 
ATOM   5447 C CA   . TRP A 1 367 ? 20.77912  -6.00491  3.37546   1.000 12.25173  ? 359 TRP A CA   1 
ATOM   5448 C C    . TRP A 1 367 ? 22.27941  -6.13034  3.58081   1.000 11.55588  ? 359 TRP A C    1 
ATOM   5449 O O    . TRP A 1 367 ? 22.79496  -5.85245  4.66988   1.000 14.22192  ? 359 TRP A O    1 
ATOM   5450 C CB   . TRP A 1 367 ? 20.16431  -7.39709  3.44349   1.000 14.56149  ? 359 TRP A CB   1 
ATOM   5451 C CG   . TRP A 1 367 ? 18.67259  -7.45961  3.32082   1.000 13.09756  ? 359 TRP A CG   1 
ATOM   5452 C CD1  . TRP A 1 367 ? 17.81464  -6.41600  3.14527   1.000 19.89291  ? 359 TRP A CD1  1 
ATOM   5453 C CD2  . TRP A 1 367 ? 17.86359  -8.64847  3.33732   1.000 12.80337  ? 359 TRP A CD2  1 
ATOM   5454 N NE1  . TRP A 1 367 ? 16.51629  -6.87665  3.07400   1.000 22.07919  ? 359 TRP A NE1  1 
ATOM   5455 C CE2  . TRP A 1 367 ? 16.51852  -8.23874  3.20712   1.000 14.87964  ? 359 TRP A CE2  1 
ATOM   5456 C CE3  . TRP A 1 367 ? 18.14250  -10.01181 3.49362   1.000 18.19284  ? 359 TRP A CE3  1 
ATOM   5457 C CZ2  . TRP A 1 367 ? 15.46279  -9.14150  3.18762   1.000 15.17300  ? 359 TRP A CZ2  1 
ATOM   5458 C CZ3  . TRP A 1 367 ? 17.08568  -10.90658 3.48096   1.000 22.51903  ? 359 TRP A CZ3  1 
ATOM   5459 C CH2  . TRP A 1 367 ? 15.76396  -10.46481 3.32914   1.000 20.25661  ? 359 TRP A CH2  1 
ATOM   5460 H H    . TRP A 1 367 ? 20.07641  -5.86904  1.53085   1.000 13.89025  ? 359 TRP A H    1 
ATOM   5461 H HA   . TRP A 1 367 ? 20.38973  -5.45840  4.07589   1.000 14.71910  ? 359 TRP A HA   1 
ATOM   5462 H HB2  . TRP A 1 367 ? 20.53412  -7.92807  2.72085   1.000 17.49080  ? 359 TRP A HB2  1 
ATOM   5463 H HB3  . TRP A 1 367 ? 20.39866  -7.79116  4.29829   1.000 17.49080  ? 359 TRP A HB3  1 
ATOM   5464 H HD1  . TRP A 1 367 ? 18.06741  -5.52321  3.08261   1.000 23.88851  ? 359 TRP A HD1  1 
ATOM   5465 H HE1  . TRP A 1 367 ? 15.81805  -6.38687  2.96370   1.000 26.51205  ? 359 TRP A HE1  1 
ATOM   5466 H HE3  . TRP A 1 367 ? 19.01678  -10.30929 3.60332   1.000 21.84843  ? 359 TRP A HE3  1 
ATOM   5467 H HZ2  . TRP A 1 367 ? 14.58436  -8.85488  3.08216   1.000 18.22462  ? 359 TRP A HZ2  1 
ATOM   5468 H HZ3  . TRP A 1 367 ? 17.25569  -11.81609 3.57478   1.000 27.03986  ? 359 TRP A HZ3  1 
ATOM   5469 H HH2  . TRP A 1 367 ? 15.07497  -11.08945 3.32476   1.000 24.32496  ? 359 TRP A HH2  1 
ATOM   5470 N N    . LEU A 1 368 ? 22.99038  -6.56132  2.54173   1.000 14.42318  ? 360 LEU A N    1 
ATOM   5471 C CA   . LEU A 1 368 ? 24.38297  -6.97761  2.65182   1.000 13.78862  ? 360 LEU A CA   1 
ATOM   5472 C C    . LEU A 1 368 ? 25.20807  -6.38141  1.52446   1.000 17.45642  ? 360 LEU A C    1 
ATOM   5473 O O    . LEU A 1 368 ? 24.81255  -6.44627  0.35572   1.000 17.48567  ? 360 LEU A O    1 
ATOM   5474 C CB   . LEU A 1 368 ? 24.49017  -8.50599  2.62271   1.000 13.87971  ? 360 LEU A CB   1 
ATOM   5475 C CG   . LEU A 1 368 ? 23.74462  -9.23603  3.74137   1.000 16.53258  ? 360 LEU A CG   1 
ATOM   5476 C CD1  . LEU A 1 368 ? 23.72032  -10.73074 3.50515   1.000 24.60288  ? 360 LEU A CD1  1 
ATOM   5477 C CD2  . LEU A 1 368 ? 24.38485  -8.90148  5.07746   1.000 24.81446  ? 360 LEU A CD2  1 
ATOM   5478 H H    . LEU A 1 368 ? 22.67846  -6.62253  1.74263   1.000 17.32484  ? 360 LEU A H    1 
ATOM   5479 H HA   . LEU A 1 368 ? 24.74648  -6.64215  3.48623   1.000 16.56337  ? 360 LEU A HA   1 
ATOM   5480 H HB2  . LEU A 1 368 ? 24.12868  -8.82107  1.77953   1.000 16.67267  ? 360 LEU A HB2  1 
ATOM   5481 H HB3  . LEU A 1 368 ? 25.42702  -8.74740  2.69292   1.000 16.67267  ? 360 LEU A HB3  1 
ATOM   5482 H HG   . LEU A 1 368 ? 22.82028  -8.94233  3.75694   1.000 19.85612  ? 360 LEU A HG   1 
ATOM   5483 H HD11 . LEU A 1 368 ? 23.30424  -11.16410 4.26672   1.000 29.54048  ? 360 LEU A HD11 1 
ATOM   5484 H HD12 . LEU A 1 368 ? 23.21082  -10.91508 2.70059   1.000 29.54048  ? 360 LEU A HD12 1 
ATOM   5485 H HD13 . LEU A 1 368 ? 24.63070  -11.04873 3.40029   1.000 29.54048  ? 360 LEU A HD13 1 
ATOM   5486 H HD21 . LEU A 1 368 ? 23.89712  -9.35383  5.78343   1.000 29.79437  ? 360 LEU A HD21 1 
ATOM   5487 H HD22 . LEU A 1 368 ? 25.30765  -9.20024  5.06907   1.000 29.79437  ? 360 LEU A HD22 1 
ATOM   5488 H HD23 . LEU A 1 368 ? 24.34912  -7.94170  5.21326   1.000 29.79437  ? 360 LEU A HD23 1 
ATOM   5489 N N    . LYS A 1 369 ? 26.35421  -5.80651  1.87901   1.000 13.14214  ? 361 LYS A N    1 
ATOM   5490 C CA   . LYS A 1 369 ? 27.30092  -5.25828  0.91765   1.000 10.02870  ? 361 LYS A CA   1 
ATOM   5491 C C    . LYS A 1 369 ? 28.53658  -6.14928  0.90586   1.000 16.78117  ? 361 LYS A C    1 
ATOM   5492 O O    . LYS A 1 369 ? 29.19664  -6.30298  1.93608   1.000 17.17969  ? 361 LYS A O    1 
ATOM   5493 C CB   . LYS A 1 369 ? 27.67575  -3.81879  1.27497   1.000 19.31889  ? 361 LYS A CB   1 
ATOM   5494 C CG   . LYS A 1 369 ? 28.75025  -3.20971  0.39849   1.000 16.39169  ? 361 LYS A CG   1 
ATOM   5495 C CD   . LYS A 1 369 ? 28.26809  -2.95364  -1.02566  1.000 18.02128  ? 361 LYS A CD   1 
ATOM   5496 C CE   . LYS A 1 369 ? 29.41425  -2.75233  -2.01097  1.000 21.63237  ? 361 LYS A CE   1 
ATOM   5497 N NZ   . LYS A 1 369 ? 30.11740  -4.03957  -2.31701  1.000 18.13029  ? 361 LYS A NZ   1 
ATOM   5498 H H    . LYS A 1 369 ? 26.61094  -5.72084  2.69531   1.000 15.78759  ? 361 LYS A H    1 
ATOM   5499 H HA   . LYS A 1 369 ? 26.90708  -5.25538  0.03120   1.000 12.05147  ? 361 LYS A HA   1 
ATOM   5500 H HB2  . LYS A 1 369 ? 26.88366  -3.26478  1.19402   1.000 23.19969  ? 361 LYS A HB2  1 
ATOM   5501 H HB3  . LYS A 1 369 ? 28.00005  -3.80245  2.18901   1.000 23.19969  ? 361 LYS A HB3  1 
ATOM   5502 H HG2  . LYS A 1 369 ? 29.02700  -2.36147  0.77901   1.000 19.68705  ? 361 LYS A HG2  1 
ATOM   5503 H HG3  . LYS A 1 369 ? 29.50599  -3.81626  0.35526   1.000 19.68705  ? 361 LYS A HG3  1 
ATOM   5504 H HD2  . LYS A 1 369 ? 27.74665  -3.71495  -1.32468  1.000 21.64256  ? 361 LYS A HD2  1 
ATOM   5505 H HD3  . LYS A 1 369 ? 27.72115  -2.15260  -1.03513  1.000 21.64256  ? 361 LYS A HD3  1 
ATOM   5506 H HE2  . LYS A 1 369 ? 29.06342  -2.39306  -2.84087  1.000 25.97587  ? 361 LYS A HE2  1 
ATOM   5507 H HE3  . LYS A 1 369 ? 30.05970  -2.13682  -1.62959  1.000 25.97587  ? 361 LYS A HE3  1 
ATOM   5508 H HZ1  . LYS A 1 369 ? 30.83285  -3.88286  -2.82265  1.000 21.77337  ? 361 LYS A HZ1  1 
ATOM   5509 H HZ2  . LYS A 1 369 ? 30.37787  -4.43124  -1.56146  1.000 21.77337  ? 361 LYS A HZ2  1 
ATOM   5510 H HZ3  . LYS A 1 369 ? 29.57003  -4.58913  -2.75343  1.000 21.77337  ? 361 LYS A HZ3  1 
ATOM   5511 N N    . THR A 1 370 ? 28.83770  -6.74375  -0.24700  1.000 18.40328  ? 362 THR A N    1 
ATOM   5512 C CA   . THR A 1 370 ? 30.00103  -7.62131  -0.35044  1.000 16.97580  ? 362 THR A CA   1 
ATOM   5513 C C    . THR A 1 370 ? 31.28020  -6.80965  -0.17457  1.000 12.37730  ? 362 THR A C    1 
ATOM   5514 O O    . THR A 1 370 ? 31.45085  -5.76045  -0.80213  1.000 19.57632  ? 362 THR A O    1 
ATOM   5515 C CB   . THR A 1 370 ? 30.01777  -8.34312  -1.69730  1.000 23.57892  ? 362 THR A CB   1 
ATOM   5516 O OG1  . THR A 1 370 ? 28.77585  -9.02637  -1.89062  1.000 22.26984  ? 362 THR A OG1  1 
ATOM   5517 C CG2  . THR A 1 370 ? 31.16671  -9.37376  -1.74218  1.000 22.94998  ? 362 THR A CG2  1 
ATOM   5518 H H    . THR A 1 370 ? 28.38970  -6.65654  -0.97589  1.000 22.10096  ? 362 THR A H    1 
ATOM   5519 H HA   . THR A 1 370 ? 29.95647  -8.29370  0.34728   1.000 20.38798  ? 362 THR A HA   1 
ATOM   5520 H HB   . THR A 1 370 ? 30.15024  -7.69615  -2.40778  1.000 28.31172  ? 362 THR A HB   1 
ATOM   5521 H HG1  . THR A 1 370 ? 28.70271  -9.26831  -2.69169  1.000 26.74083  ? 362 THR A HG1  1 
ATOM   5522 H HG21 . THR A 1 370 ? 31.15623  -9.84559  -2.58963  1.000 27.55700  ? 362 THR A HG21 1 
ATOM   5523 H HG22 . THR A 1 370 ? 32.02022  -8.92365  -1.64303  1.000 27.55700  ? 362 THR A HG22 1 
ATOM   5524 H HG23 . THR A 1 370 ? 31.06426  -10.01635 -1.02282  1.000 27.55700  ? 362 THR A HG23 1 
ATOM   5525 N N    . ILE A 1 371 ? 32.17313  -7.29054  0.69342   1.000 23.07107  ? 363 ILE A N    1 
ATOM   5526 C CA   . ILE A 1 371 ? 33.35955  -6.51704  1.02668   1.000 22.70436  ? 363 ILE A CA   1 
ATOM   5527 C C    . ILE A 1 371 ? 34.31098  -6.49885  -0.16075  1.000 23.42874  ? 363 ILE A C    1 
ATOM   5528 O O    . ILE A 1 371 ? 34.34350  -7.42402  -0.98663  1.000 24.97420  ? 363 ILE A O    1 
ATOM   5529 C CB   . ILE A 1 371 ? 34.06036  -7.07391  2.28083   1.000 23.75040  ? 363 ILE A CB   1 
ATOM   5530 C CG1  . ILE A 1 371 ? 34.66772  -8.44660  1.99122   1.000 47.55323  ? 363 ILE A CG1  1 
ATOM   5531 C CG2  . ILE A 1 371 ? 33.09310  -7.13979  3.45566   1.000 28.08821  ? 363 ILE A CG2  1 
ATOM   5532 C CD1  . ILE A 1 371 ? 35.63188  -8.93014  3.06836   1.000 47.28980  ? 363 ILE A CD1  1 
ATOM   5533 H H    . ILE A 1 371 ? 32.11261  -8.04916  1.09395   1.000 27.70230  ? 363 ILE A H    1 
ATOM   5534 H HA   . ILE A 1 371 ? 33.08449  -5.60745  1.22135   1.000 27.26226  ? 363 ILE A HA   1 
ATOM   5535 H HB   . ILE A 1 371 ? 34.78068  -6.46964  2.51935   1.000 28.51750  ? 363 ILE A HB   1 
ATOM   5536 H HG12 . ILE A 1 371 ? 33.95104  -9.09655  1.92176   1.000 57.08090  ? 363 ILE A HG12 1 
ATOM   5537 H HG13 . ILE A 1 371 ? 35.15669  -8.40126  1.15470   1.000 57.08090  ? 363 ILE A HG13 1 
ATOM   5538 H HG21 . ILE A 1 371 ? 33.58242  -7.39386  4.25373   1.000 33.72287  ? 363 ILE A HG21 1 
ATOM   5539 H HG22 . ILE A 1 371 ? 32.68745  -6.26751  3.58003   1.000 33.72287  ? 363 ILE A HG22 1 
ATOM   5540 H HG23 . ILE A 1 371 ? 32.40781  -7.79898  3.26393   1.000 33.72287  ? 363 ILE A HG23 1 
ATOM   5541 H HD11 . ILE A 1 371 ? 36.01219  -9.77917  2.79373   1.000 56.76478  ? 363 ILE A HD11 1 
ATOM   5542 H HD12 . ILE A 1 371 ? 36.33635  -8.27273  3.17983   1.000 56.76478  ? 363 ILE A HD12 1 
ATOM   5543 H HD13 . ILE A 1 371 ? 35.14633  -9.03907  3.90100   1.000 56.76478  ? 363 ILE A HD13 1 
ATOM   5544 N N    . ASN A 1 372 ? 35.11112  -5.44020  -0.23651  1.000 27.01562  ? 364 ASN A N    1 
ATOM   5545 C CA   . ASN A 1 372 ? 36.17735  -5.33969  -1.22829  1.000 41.44982  ? 364 ASN A CA   1 
ATOM   5546 C C    . ASN A 1 372 ? 35.64133  -5.45772  -2.64684  1.000 37.52703  ? 364 ASN A C    1 
ATOM   5547 O O    . ASN A 1 372 ? 36.30752  -6.00528  -3.52827  1.000 31.47688  ? 364 ASN A O    1 
ATOM   5548 C CB   . ASN A 1 372 ? 37.25256  -6.39845  -0.97760  1.000 33.57774  ? 364 ASN A CB   1 
ATOM   5549 C CG   . ASN A 1 372 ? 37.95063  -6.20466  0.35343   1.000 31.54220  ? 364 ASN A CG   1 
ATOM   5550 O OD1  . ASN A 1 372 ? 37.88182  -5.12641  0.94670   1.000 36.98025  ? 364 ASN A OD1  1 
ATOM   5551 N ND2  . ASN A 1 372 ? 38.62407  -7.24549  0.83150   1.000 47.44310  ? 364 ASN A ND2  1 
ATOM   5552 H H    . ASN A 1 372 ? 35.05574  -4.75710  0.28301   1.000 32.43577  ? 364 ASN A H    1 
ATOM   5553 H HA   . ASN A 1 372 ? 36.58676  -4.46396  -1.14839  1.000 49.75681  ? 364 ASN A HA   1 
ATOM   5554 H HB2  . ASN A 1 372 ? 36.84020  -7.27644  -0.97726  1.000 40.31031  ? 364 ASN A HB2  1 
ATOM   5555 H HB3  . ASN A 1 372 ? 37.92028  -6.34580  -1.67922  1.000 40.31031  ? 364 ASN A HB3  1 
ATOM   5556 H HD21 . ASN A 1 372 ? 39.03618  -7.18228  1.58367   1.000 56.94874  ? 364 ASN A HD21 1 
ATOM   5557 H HD22 . ASN A 1 372 ? 38.64785  -7.98238  0.38875   1.000 56.94874  ? 364 ASN A HD22 1 
ATOM   5558 N N    . ARG A 1 373 ? 34.42896  -4.95650  -2.86902  1.000 34.04390  ? 365 ARG A N    1 
ATOM   5559 C CA   . ARG A 1 373 ? 33.84740  -4.87996  -4.20265  1.000 25.55242  ? 365 ARG A CA   1 
ATOM   5560 C C    . ARG A 1 373 ? 33.23487  -3.50010  -4.35884  1.000 27.63947  ? 365 ARG A C    1 
ATOM   5561 O O    . ARG A 1 373 ? 32.40790  -3.09018  -3.53946  1.000 26.06166  ? 365 ARG A O    1 
ATOM   5562 C CB   . ARG A 1 373 ? 32.79497  -5.97005  -4.42899  1.000 28.11780  ? 365 ARG A CB   1 
ATOM   5563 C CG   . ARG A 1 373 ? 33.32976  -7.39364  -4.31490  1.000 37.88467  ? 365 ARG A CG   1 
ATOM   5564 C CD   . ARG A 1 373 ? 34.30711  -7.71573  -5.43687  1.000 37.08235  ? 365 ARG A CD   1 
ATOM   5565 N NE   . ARG A 1 373 ? 33.62927  -7.95127  -6.70962  1.000 36.87487  ? 365 ARG A NE   1 
ATOM   5566 C CZ   . ARG A 1 373 ? 33.10101  -9.11443  -7.07673  1.000 32.95424  ? 365 ARG A CZ   1 
ATOM   5567 N NH1  . ARG A 1 373 ? 33.16892  -10.16464 -6.26755  1.000 45.96972  ? 365 ARG A NH1  1 
ATOM   5568 N NH2  . ARG A 1 373 ? 32.50520  -9.22684  -8.25837  1.000 48.22949  ? 365 ARG A NH2  1 
ATOM   5569 H H    . ARG A 1 373 ? 33.91579  -4.64926  -2.25107  1.000 40.86971  ? 365 ARG A H    1 
ATOM   5570 H HA   . ARG A 1 373 ? 34.54059  -4.99966  -4.87053  1.000 30.67993  ? 365 ARG A HA   1 
ATOM   5571 H HB2  . ARG A 1 373 ? 32.09398  -5.86577  -3.76669  1.000 33.75838  ? 365 ARG A HB2  1 
ATOM   5572 H HB3  . ARG A 1 373 ? 32.42739  -5.86504  -5.32048  1.000 33.75838  ? 365 ARG A HB3  1 
ATOM   5573 H HG2  . ARG A 1 373 ? 33.79295  -7.49577  -3.46878  1.000 45.47863  ? 365 ARG A HG2  1 
ATOM   5574 H HG3  . ARG A 1 373 ? 32.59038  -8.01944  -4.36601  1.000 45.47863  ? 365 ARG A HG3  1 
ATOM   5575 H HD2  . ARG A 1 373 ? 34.91604  -6.96960  -5.55255  1.000 44.51585  ? 365 ARG A HD2  1 
ATOM   5576 H HD3  . ARG A 1 373 ? 34.80362  -8.51652  -5.20640  1.000 44.51585  ? 365 ARG A HD3  1 
ATOM   5577 H HE   . ARG A 1 373 ? 33.56789  -7.29229  -7.25877  1.000 44.26687  ? 365 ARG A HE   1 
ATOM   5578 H HH11 . ARG A 1 373 ? 33.55574  -10.09388 -5.50272  1.000 55.18068  ? 365 ARG A HH11 1 
ATOM   5579 H HH12 . ARG A 1 373 ? 32.82609  -10.91575 -6.50818  1.000 55.18068  ? 365 ARG A HH12 1 
ATOM   5580 H HH21 . ARG A 1 373 ? 32.46174  -8.54783  -8.78435  1.000 57.89241  ? 365 ARG A HH21 1 
ATOM   5581 H HH22 . ARG A 1 373 ? 32.16287  -9.97864  -8.49754  1.000 57.89241  ? 365 ARG A HH22 1 
ATOM   5582 N N    . ASP A 1 374 ? 33.64041  -2.79022  -5.40171  1.000 25.57322  ? 366 ASP A N    1 
ATOM   5583 C CA   . ASP A 1 374 ? 33.17008  -1.44047  -5.65351  1.000 22.50406  ? 366 ASP A CA   1 
ATOM   5584 C C    . ASP A 1 374 ? 31.91368  -1.45906  -6.51674  1.000 21.02992  ? 366 ASP A C    1 
ATOM   5585 O O    . ASP A 1 374 ? 31.69955  -2.36320  -7.33121  1.000 24.66935  ? 366 ASP A O    1 
ATOM   5586 C CB   . ASP A 1 374 ? 34.25573  -0.61053  -6.34803  1.000 32.38456  ? 366 ASP A CB   1 
ATOM   5587 C CG   . ASP A 1 374 ? 35.49560  -0.42556  -5.49549  1.000 35.84900  ? 366 ASP A CG   1 
ATOM   5588 O OD1  . ASP A 1 374 ? 35.40433  -0.56112  -4.25780  1.000 33.72620  ? 366 ASP A OD1  1 
ATOM   5589 O OD2  . ASP A 1 374 ? 36.56849  -0.14263  -6.06981  1.000 50.76774  ? 366 ASP A OD2  1 
ATOM   5590 H H    . ASP A 1 374 ? 34.19956  -3.07563  -5.98949  1.000 30.70489  ? 366 ASP A H    1 
ATOM   5591 H HA   . ASP A 1 374 ? 32.95298  -1.01769  -4.80792  1.000 27.02189  ? 366 ASP A HA   1 
ATOM   5592 H HB2  . ASP A 1 374 ? 34.51993  -1.05891  -7.16660  1.000 38.87849  ? 366 ASP A HB2  1 
ATOM   5593 H HB3  . ASP A 1 374 ? 33.89893  0.26823   -6.55141  1.000 38.87849  ? 366 ASP A HB3  1 
ATOM   5594 N N    . VAL A 1 375 ? 31.09551  -0.42837  -6.34993  1.000 23.05418  ? 367 VAL A N    1 
ATOM   5595 C CA   . VAL A 1 375 ? 29.86323  -0.27173  -7.11164  1.000 24.12431  ? 367 VAL A CA   1 
ATOM   5596 C C    . VAL A 1 375 ? 30.12742  0.65867   -8.28967  1.000 22.58990  ? 367 VAL A C    1 
ATOM   5597 O O    . VAL A 1 375 ? 30.47247  1.83187   -8.10532  1.000 25.72720  ? 367 VAL A O    1 
ATOM   5598 C CB   . VAL A 1 375 ? 28.72723  0.26902   -6.23142  1.000 28.58432  ? 367 VAL A CB   1 
ATOM   5599 C CG1  . VAL A 1 375 ? 27.50472  0.57598   -7.08376  1.000 28.46689  ? 367 VAL A CG1  1 
ATOM   5600 C CG2  . VAL A 1 375 ? 28.40829  -0.71493  -5.12943  1.000 27.81406  ? 367 VAL A CG2  1 
ATOM   5601 H H    . VAL A 1 375 ? 31.23579  0.20785   -5.78856  1.000 27.68204  ? 367 VAL A H    1 
ATOM   5602 H HA   . VAL A 1 375 ? 29.60131  -1.13656  -7.46428  1.000 28.96619  ? 367 VAL A HA   1 
ATOM   5603 H HB   . VAL A 1 375 ? 29.00511  1.09765   -5.81064  1.000 34.31821  ? 367 VAL A HB   1 
ATOM   5604 H HG11 . VAL A 1 375 ? 26.74603  0.73722   -6.50128  1.000 34.17729  ? 367 VAL A HG11 1 
ATOM   5605 H HG12 . VAL A 1 375 ? 27.68346  1.36427   -7.62000  1.000 34.17729  ? 367 VAL A HG12 1 
ATOM   5606 H HG13 . VAL A 1 375 ? 27.32348  -0.18242  -7.66072  1.000 34.17729  ? 367 VAL A HG13 1 
ATOM   5607 H HG21 . VAL A 1 375 ? 27.66134  -0.37716  -4.61090  1.000 33.39390  ? 367 VAL A HG21 1 
ATOM   5608 H HG22 . VAL A 1 375 ? 28.17616  -1.56910  -5.52618  1.000 33.39390  ? 367 VAL A HG22 1 
ATOM   5609 H HG23 . VAL A 1 375 ? 29.18744  -0.81532  -4.56044  1.000 33.39390  ? 367 VAL A HG23 1 
ATOM   5610 N N    . SER A 1 376 ? 29.93716  0.14624   -9.50024  1.000 22.75494  ? 368 SER A N    1 
ATOM   5611 C CA   . SER A 1 376 ? 30.07870  0.94268   -10.70968 1.000 25.31287  ? 368 SER A CA   1 
ATOM   5612 C C    . SER A 1 376 ? 28.75238  1.62734   -11.01253 1.000 25.89635  ? 368 SER A C    1 
ATOM   5613 O O    . SER A 1 376 ? 27.71911  0.96014   -11.15170 1.000 26.61176  ? 368 SER A O    1 
ATOM   5614 C CB   . SER A 1 376 ? 30.51105  0.06443   -11.88286 1.000 32.97496  ? 368 SER A CB   1 
ATOM   5615 O OG   . SER A 1 376 ? 31.81192  -0.45738  -11.66909 1.000 35.32283  ? 368 SER A OG   1 
ATOM   5616 H H    . SER A 1 376 ? 29.72209  -0.67324  -9.64790  1.000 27.32295  ? 368 SER A H    1 
ATOM   5617 H HA   . SER A 1 376 ? 30.75506  1.62452   -10.57353 1.000 30.39247  ? 368 SER A HA   1 
ATOM   5618 H HB2  . SER A 1 376 ? 29.88623  -0.67201  -11.97319 1.000 39.58698  ? 368 SER A HB2  1 
ATOM   5619 H HB3  . SER A 1 376 ? 30.51401  0.59824   -12.69276 1.000 39.58698  ? 368 SER A HB3  1 
ATOM   5620 H HG   . SER A 1 376 ? 32.03315  -0.95007  -12.31245 1.000 42.40442  ? 368 SER A HG   1 
ATOM   5621 N N    . ILE A 1 377 ? 28.78392  2.94544   -11.12108 1.000 20.29728  ? 369 ILE A N    1 
ATOM   5622 C CA   . ILE A 1 377 ? 27.60082  3.73772   -11.42846 1.000 22.73515  ? 369 ILE A CA   1 
ATOM   5623 C C    . ILE A 1 377 ? 27.49927  3.89586   -12.93799 1.000 38.93289  ? 369 ILE A C    1 
ATOM   5624 O O    . ILE A 1 377 ? 28.49331  4.16961   -13.61830 1.000 27.16821  ? 369 ILE A O    1 
ATOM   5625 C CB   . ILE A 1 377 ? 27.65662  5.10490   -10.72404 1.000 21.90780  ? 369 ILE A CB   1 
ATOM   5626 C CG1  . ILE A 1 377 ? 27.82455  4.91813   -9.21232  1.000 30.61699  ? 369 ILE A CG1  1 
ATOM   5627 C CG2  . ILE A 1 377 ? 26.41938  5.92016   -11.02482 1.000 22.17226  ? 369 ILE A CG2  1 
ATOM   5628 C CD1  . ILE A 1 377 ? 26.74528  4.08875   -8.55026  1.000 22.17031  ? 369 ILE A CD1  1 
ATOM   5629 H H    . ILE A 1 377 ? 29.49554  3.41739   -11.01888 1.000 24.37375  ? 369 ILE A H    1 
ATOM   5630 H HA   . ILE A 1 377 ? 26.81132  3.27054   -11.11327 1.000 27.29920  ? 369 ILE A HA   1 
ATOM   5631 H HB   . ILE A 1 377 ? 28.42574  5.58769   -11.06503 1.000 26.30638  ? 369 ILE A HB   1 
ATOM   5632 H HG12 . ILE A 1 377 ? 28.67264  4.47651   -9.04921  1.000 36.75741  ? 369 ILE A HG12 1 
ATOM   5633 H HG13 . ILE A 1 377 ? 27.81941  5.79225   -8.79187  1.000 36.75741  ? 369 ILE A HG13 1 
ATOM   5634 H HG21 . ILE A 1 377 ? 26.40916  6.70206   -10.45087 1.000 26.62373  ? 369 ILE A HG21 1 
ATOM   5635 H HG22 . ILE A 1 377 ? 26.43957  6.19315   -11.95539 1.000 26.62373  ? 369 ILE A HG22 1 
ATOM   5636 H HG23 . ILE A 1 377 ? 25.63411  5.37612   -10.85667 1.000 26.62373  ? 369 ILE A HG23 1 
ATOM   5637 H HD11 . ILE A 1 377 ? 26.83308  4.16677   -7.58740  1.000 26.62140  ? 369 ILE A HD11 1 
ATOM   5638 H HD12 . ILE A 1 377 ? 25.87714  4.41801   -8.83101  1.000 26.62140  ? 369 ILE A HD12 1 
ATOM   5639 H HD13 . ILE A 1 377 ? 26.85008  3.16233   -8.81797  1.000 26.62140  ? 369 ILE A HD13 1 
ATOM   5640 N N    . CYS A 1 378 ? 26.28894  3.72815   -13.46320 1.000 22.02190  ? 370 CYS A N    1 
ATOM   5641 C CA   . CYS A 1 378 ? 26.04568  3.65133   -14.89640 1.000 24.29435  ? 370 CYS A CA   1 
ATOM   5642 C C    . CYS A 1 378 ? 24.91619  4.59468   -15.28623 1.000 24.98351  ? 370 CYS A C    1 
ATOM   5643 O O    . CYS A 1 378 ? 23.99168  4.84236   -14.50574 1.000 31.58120  ? 370 CYS A O    1 
ATOM   5644 C CB   . CYS A 1 378 ? 25.67934  2.19938   -15.32584 1.000 21.11682  ? 370 CYS A CB   1 
ATOM   5645 S SG   . CYS A 1 378 ? 26.94135  0.95976   -14.92972 1.000 35.62157  ? 370 CYS A SG   1 
ATOM   5646 H H    . CYS A 1 378 ? 25.57226  3.65419   -12.99361 1.000 26.44330  ? 370 CYS A H    1 
ATOM   5647 H HA   . CYS A 1 378 ? 26.84438  3.92749   -15.37256 1.000 29.17024  ? 370 CYS A HA   1 
ATOM   5648 H HB2  . CYS A 1 378 ? 24.86136  1.94028   -14.87341 1.000 25.35721  ? 370 CYS A HB2  1 
ATOM   5649 H HB3  . CYS A 1 378 ? 25.54580  2.18553   -16.28650 1.000 25.35721  ? 370 CYS A HB3  1 
ATOM   5650 H HG   . CYS A 1 378 ? 27.95410  1.23329   -15.51239 1.000 42.76290  ? 370 CYS A HG   1 
ATOM   5651 N N    . GLU A 1 379 ? 24.98811  5.10442   -16.51763 1.000 22.24240  ? 371 GLU A N    1 
ATOM   5652 C CA   . GLU A 1 379 ? 23.92326  5.89822   -17.10784 1.000 21.52386  ? 371 GLU A CA   1 
ATOM   5653 C C    . GLU A 1 379 ? 23.77319  5.48754   -18.56947 1.000 23.04674  ? 371 GLU A C    1 
ATOM   5654 O O    . GLU A 1 379 ? 24.78049  5.23363   -19.24450 1.000 28.39480  ? 371 GLU A O    1 
ATOM   5655 C CB   . GLU A 1 379 ? 24.20511  7.40397   -17.01108 1.000 24.80763  ? 371 GLU A CB   1 
ATOM   5656 C CG   . GLU A 1 379 ? 24.28445  7.93116   -15.58171 1.000 30.06122  ? 371 GLU A CG   1 
ATOM   5657 C CD   . GLU A 1 379 ? 22.93945  7.94782   -14.87507 1.000 34.55020  ? 371 GLU A CD   1 
ATOM   5658 O OE1  . GLU A 1 379 ? 21.89772  7.92388   -15.56149 1.000 31.40118  ? 371 GLU A OE1  1 
ATOM   5659 O OE2  . GLU A 1 379 ? 22.92230  7.99214   -13.62675 1.000 26.94238  ? 371 GLU A OE2  1 
ATOM   5660 H H    . GLU A 1 379 ? 25.66338  4.99815   -17.03947 1.000 26.70791  ? 371 GLU A H    1 
ATOM   5661 H HA   . GLU A 1 379 ? 23.08941  5.72321   -16.64420 1.000 25.84565  ? 371 GLU A HA   1 
ATOM   5662 H HB2  . GLU A 1 379 ? 25.05451  7.58929   -17.44129 1.000 29.78618  ? 371 GLU A HB2  1 
ATOM   5663 H HB3  . GLU A 1 379 ? 23.49288  7.88298   -17.46293 1.000 29.78618  ? 371 GLU A HB3  1 
ATOM   5664 H HG2  . GLU A 1 379 ? 24.88297  7.36450   -15.07027 1.000 36.09049  ? 371 GLU A HG2  1 
ATOM   5665 H HG3  . GLU A 1 379 ? 24.62291  8.84001   -15.60005 1.000 36.09049  ? 371 GLU A HG3  1 
ATOM   5666 N N    . PRO A 1 380 ? 22.54362  5.38553   -19.07732 1.000 23.69574  ? 372 PRO A N    1 
ATOM   5667 C CA   . PRO A 1 380 ? 22.36237  4.97583   -20.47680 1.000 21.17281  ? 372 PRO A CA   1 
ATOM   5668 C C    . PRO A 1 380 ? 22.58457  6.13378   -21.43436 1.000 20.59902  ? 372 PRO A C    1 
ATOM   5669 O O    . PRO A 1 380 ? 22.18064  7.26796   -21.16972 1.000 25.50111  ? 372 PRO A O    1 
ATOM   5670 C CB   . PRO A 1 380 ? 20.90568  4.49828   -20.52215 1.000 21.16734  ? 372 PRO A CB   1 
ATOM   5671 C CG   . PRO A 1 380 ? 20.22236  5.33127   -19.48948 1.000 24.66918  ? 372 PRO A CG   1 
ATOM   5672 C CD   . PRO A 1 380 ? 21.25445  5.62014   -18.40066 1.000 24.34933  ? 372 PRO A CD   1 
ATOM   5673 H HA   . PRO A 1 380 ? 22.95819  4.24395   -20.70097 1.000 25.42440  ? 372 PRO A HA   1 
ATOM   5674 H HB2  . PRO A 1 380 ? 20.53013  4.65326   -21.40297 1.000 25.41784  ? 372 PRO A HB2  1 
ATOM   5675 H HB3  . PRO A 1 380 ? 20.85588  3.55502   -20.30154 1.000 25.41784  ? 372 PRO A HB3  1 
ATOM   5676 H HG2  . PRO A 1 380 ? 19.91368  6.15751   -19.89313 1.000 29.62004  ? 372 PRO A HG2  1 
ATOM   5677 H HG3  . PRO A 1 380 ? 19.47050  4.83973   -19.12343 1.000 29.62004  ? 372 PRO A HG3  1 
ATOM   5678 H HD2  . PRO A 1 380 ? 21.18695  6.53895   -18.09713 1.000 29.23622  ? 372 PRO A HD2  1 
ATOM   5679 H HD3  . PRO A 1 380 ? 21.14344  5.01421   -17.65137 1.000 29.23622  ? 372 PRO A HD3  1 
ATOM   5680 N N    . THR A 1 381 ? 23.25341  5.82940   -22.55257 1.000 23.02934  ? 373 THR A N    1 
ATOM   5681 C CA   . THR A 1 381 ? 23.43528  6.79945   -23.62653 1.000 24.07818  ? 373 THR A CA   1 
ATOM   5682 C C    . THR A 1 381 ? 22.21224  6.87610   -24.52284 1.000 44.67387  ? 373 THR A C    1 
ATOM   5683 O O    . THR A 1 381 ? 22.00970  7.88908   -25.20170 1.000 44.99014  ? 373 THR A O    1 
ATOM   5684 C CB   . THR A 1 381 ? 24.65268  6.43487   -24.48419 1.000 25.67551  ? 373 THR A CB   1 
ATOM   5685 O OG1  . THR A 1 381 ? 24.40970  5.18911   -25.14604 1.000 41.21180  ? 373 THR A OG1  1 
ATOM   5686 C CG2  . THR A 1 381 ? 25.90187  6.30629   -23.63988 1.000 42.31303  ? 373 THR A CG2  1 
ATOM   5687 H H    . THR A 1 381 ? 23.61149  5.06358   -22.71036 1.000 27.65224  ? 373 THR A H    1 
ATOM   5688 H HA   . THR A 1 381 ? 23.60067  7.67071   -23.23354 1.000 28.91084  ? 373 THR A HA   1 
ATOM   5689 H HB   . THR A 1 381 ? 24.80138  7.13747   -25.13622 1.000 30.82764  ? 373 THR A HB   1 
ATOM   5690 H HG1  . THR A 1 381 ? 25.06394  4.99068   -25.63410 1.000 49.47119  ? 373 THR A HG1  1 
ATOM   5691 H HG21 . THR A 1 381 ? 26.65720  6.06664   -24.19930 1.000 50.79265  ? 373 THR A HG21 1 
ATOM   5692 H HG22 . THR A 1 381 ? 26.09199  7.14874   -23.19825 1.000 50.79265  ? 373 THR A HG22 1 
ATOM   5693 H HG23 . THR A 1 381 ? 25.77806  5.61892   -22.96676 1.000 50.79265  ? 373 THR A HG23 1 
ATOM   5694 N N    . ARG A 1 382 ? 21.40838  5.82043   -24.55118 1.000 32.68857  ? 374 ARG A N    1 
ATOM   5695 C CA   . ARG A 1 382 ? 20.17760  5.78403   -25.31763 1.000 31.39108  ? 374 ARG A CA   1 
ATOM   5696 C C    . ARG A 1 382 ? 18.99079  5.79707   -24.36612 1.000 46.02674  ? 374 ARG A C    1 
ATOM   5697 O O    . ARG A 1 382 ? 19.08468  5.39728   -23.20497 1.000 29.11879  ? 374 ARG A O    1 
ATOM   5698 C CB   . ARG A 1 382 ? 20.11934  4.54797   -26.21877 1.000 38.98835  ? 374 ARG A CB   1 
ATOM   5699 C CG   . ARG A 1 382 ? 19.05377  4.63642   -27.30372 1.000 72.05941  ? 374 ARG A CG   1 
ATOM   5700 C CD   . ARG A 1 382 ? 19.05055  3.38296   -28.17146 1.000 65.37239  ? 374 ARG A CD   1 
ATOM   5701 N NE   . ARG A 1 382 ? 17.69463  2.92627   -28.46220 1.000 45.04757  ? 374 ARG A NE   1 
ATOM   5702 C CZ   . ARG A 1 382 ? 17.38099  1.68633   -28.82367 1.000 56.17264  ? 374 ARG A CZ   1 
ATOM   5703 N NH1  . ARG A 1 382 ? 18.33699  0.76881   -28.93813 1.000 41.18555  ? 374 ARG A NH1  1 
ATOM   5704 N NH2  . ARG A 1 382 ? 16.10884  1.36866   -29.07022 1.000 29.09671  ? 374 ARG A NH2  1 
ATOM   5705 H H    . ARG A 1 382 ? 21.56251  5.09250   -24.11996 1.000 39.24330  ? 374 ARG A H    1 
ATOM   5706 H HA   . ARG A 1 382 ? 20.12591  6.56452   -25.89127 1.000 37.68631  ? 374 ARG A HA   1 
ATOM   5707 H HB2  . ARG A 1 382 ? 20.97886  4.43797   -26.65468 1.000 46.80304  ? 374 ARG A HB2  1 
ATOM   5708 H HB3  . ARG A 1 382 ? 19.92288  3.77127   -25.67192 1.000 46.80304  ? 374 ARG A HB3  1 
ATOM   5709 H HG2  . ARG A 1 382 ? 18.18017  4.72667   -26.89191 1.000 86.48832  ? 374 ARG A HG2  1 
ATOM   5710 H HG3  . ARG A 1 382 ? 19.23360  5.40208   -27.87146 1.000 86.48832  ? 374 ARG A HG3  1 
ATOM   5711 H HD2  . ARG A 1 382 ? 19.49293  3.57556   -29.01295 1.000 78.46389  ? 374 ARG A HD2  1 
ATOM   5712 H HD3  . ARG A 1 382 ? 19.51743  2.67109   -27.70653 1.000 78.46389  ? 374 ARG A HD3  1 
ATOM   5713 H HE   . ARG A 1 382 ? 17.05582  3.49813   -28.39504 1.000 54.07411  ? 374 ARG A HE   1 
ATOM   5714 H HH11 . ARG A 1 382 ? 19.15559  0.97852   -28.77839 1.000 49.43968  ? 374 ARG A HH11 1 
ATOM   5715 H HH12 . ARG A 1 382 ? 18.13656  -0.03417  -29.17187 1.000 49.43968  ? 374 ARG A HH12 1 
ATOM   5716 H HH21 . ARG A 1 382 ? 15.49427  1.96554   -28.99510 1.000 34.93307  ? 374 ARG A HH21 1 
ATOM   5717 H HH22 . ARG A 1 382 ? 15.90340  0.56703   -29.30426 1.000 34.93307  ? 374 ARG A HH22 1 
ATOM   5718 N N    . LYS A 1 383 ? 17.86980  6.26540   -24.87581 1.000 26.07012  ? 375 LYS A N    1 
ATOM   5719 C CA   . LYS A 1 383 ? 16.68768  6.45744   -24.05399 1.000 37.28595  ? 375 LYS A CA   1 
ATOM   5720 C C    . LYS A 1 383 ? 16.01739  5.13230   -23.71584 1.000 32.14479  ? 375 LYS A C    1 
ATOM   5721 O O    . LYS A 1 383 ? 15.93627  4.22246   -24.54770 1.000 25.37298  ? 375 LYS A O    1 
ATOM   5722 C CB   . LYS A 1 383 ? 15.71273  7.36090   -24.78838 1.000 47.32127  ? 375 LYS A CB   1 
ATOM   5723 C CG   . LYS A 1 383 ? 15.24171  6.73717   -26.04543 1.000 78.22319  ? 375 LYS A CG   1 
ATOM   5724 C CD   . LYS A 1 383 ? 13.81617  6.49387   -25.94029 1.000 82.62623  ? 375 LYS A CD   1 
ATOM   5725 C CE   . LYS A 1 383 ? 13.48680  5.96330   -27.22849 1.000 79.68936  ? 375 LYS A CE   1 
ATOM   5726 N NZ   . LYS A 1 383 ? 12.22524  5.23916   -26.82038 1.000 73.46980  ? 375 LYS A NZ   1 
ATOM   5727 H H    . LYS A 1 383 ? 17.76300  6.48250   -25.70107 1.000 31.30116  ? 375 LYS A H    1 
ATOM   5728 H HA   . LYS A 1 383 ? 16.94225  6.87162   -23.21461 1.000 44.76016  ? 375 LYS A HA   1 
ATOM   5729 H HB2  . LYS A 1 383 ? 14.94286  7.52936   -24.22286 1.000 56.80254  ? 375 LYS A HB2  1 
ATOM   5730 H HB3  . LYS A 1 383 ? 16.15272  8.19712   -25.00754 1.000 56.80254  ? 375 LYS A HB3  1 
ATOM   5731 H HG2  . LYS A 1 383 ? 15.40654  7.33270   -26.79314 1.000 93.88485  ? 375 LYS A HG2  1 
ATOM   5732 H HG3  . LYS A 1 383 ? 15.69702  5.89252   -26.18740 1.000 93.88485  ? 375 LYS A HG3  1 
ATOM   5733 H HD2  . LYS A 1 383 ? 13.61846  5.84674   -25.24529 1.000 99.16850  ? 375 LYS A HD2  1 
ATOM   5734 H HD3  . LYS A 1 383 ? 13.32849  7.31619   -25.77638 1.000 99.16850  ? 375 LYS A HD3  1 
ATOM   5735 H HE2  . LYS A 1 383 ? 13.31043  6.65647   -27.88371 1.000 95.64426  ? 375 LYS A HE2  1 
ATOM   5736 H HE3  . LYS A 1 383 ? 14.16180  5.35312   -27.56457 1.000 95.64426  ? 375 LYS A HE3  1 
ATOM   5737 H HZ1  . LYS A 1 383 ? 11.87811  4.81401   -27.52098 1.000 88.18078  ? 375 LYS A HZ1  1 
ATOM   5738 H HZ2  . LYS A 1 383 ? 12.40781  4.64502   -26.18338 1.000 88.18078  ? 375 LYS A HZ2  1 
ATOM   5739 H HZ3  . LYS A 1 383 ? 11.62725  5.82074   -26.51010 1.000 88.18078  ? 375 LYS A HZ3  1 
ATOM   5740 N N    . ILE A 1 384 ? 15.52215  5.04357   -22.48548 1.000 24.49564  ? 376 ILE A N    1 
ATOM   5741 C CA   . ILE A 1 384 ? 14.86656  3.84864   -21.96705 1.000 22.91523  ? 376 ILE A CA   1 
ATOM   5742 C C    . ILE A 1 384 ? 13.35845  4.04273   -22.05505 1.000 16.63903  ? 376 ILE A C    1 
ATOM   5743 O O    . ILE A 1 384 ? 12.84437  5.10675   -21.69131 1.000 20.32909  ? 376 ILE A O    1 
ATOM   5744 C CB   . ILE A 1 384 ? 15.29488  3.58812   -20.51120 1.000 26.15590  ? 376 ILE A CB   1 
ATOM   5745 C CG1  . ILE A 1 384 ? 16.80352  3.34484   -20.42292 1.000 30.80364  ? 376 ILE A CG1  1 
ATOM   5746 C CG2  . ILE A 1 384 ? 14.52318  2.43374   -19.90436 1.000 27.20027  ? 376 ILE A CG2  1 
ATOM   5747 C CD1  . ILE A 1 384 ? 17.27360  2.09777   -21.11086 1.000 27.77669  ? 376 ILE A CD1  1 
ATOM   5748 H H    . ILE A 1 384 ? 15.55536  5.68478   -21.91333 1.000 29.41179  ? 376 ILE A H    1 
ATOM   5749 H HA   . ILE A 1 384 ? 15.10793  3.08326   -22.51187 1.000 27.51529  ? 376 ILE A HA   1 
ATOM   5750 H HB   . ILE A 1 384 ? 15.08518  4.38446   -19.99860 1.000 31.40410  ? 376 ILE A HB   1 
ATOM   5751 H HG12 . ILE A 1 384 ? 17.26203  4.09550   -20.83181 1.000 36.98139  ? 376 ILE A HG12 1 
ATOM   5752 H HG13 . ILE A 1 384 ? 17.05097  3.27445   -19.48766 1.000 36.98139  ? 376 ILE A HG13 1 
ATOM   5753 H HG21 . ILE A 1 384 ? 14.92496  2.19783   -19.05359 1.000 32.65735  ? 376 ILE A HG21 1 
ATOM   5754 H HG22 . ILE A 1 384 ? 13.60160  2.70539   -19.77094 1.000 32.65735  ? 376 ILE A HG22 1 
ATOM   5755 H HG23 . ILE A 1 384 ? 14.56051  1.67629   -20.50915 1.000 32.65735  ? 376 ILE A HG23 1 
ATOM   5756 H HD11 . ILE A 1 384 ? 18.23022  2.00592   -20.97918 1.000 33.34905  ? 376 ILE A HD11 1 
ATOM   5757 H HD12 . ILE A 1 384 ? 16.81246  1.33407   -20.73006 1.000 33.34905  ? 376 ILE A HD12 1 
ATOM   5758 H HD13 . ILE A 1 384 ? 17.07507  2.16556   -22.05790 1.000 33.34905  ? 376 ILE A HD13 1 
ATOM   5759 N N    . ARG A 1 385 ? 12.64569  3.01684   -22.54590 1.000 15.43520  ? 377 ARG A N    1 
ATOM   5760 C CA   . ARG A 1 385 ? 11.19432  2.94845   -22.45116 1.000 15.20807  ? 377 ARG A CA   1 
ATOM   5761 C C    . ARG A 1 385 ? 10.90223  2.15797   -21.18527 1.000 17.17411  ? 377 ARG A C    1 
ATOM   5762 O O    . ARG A 1 385 ? 10.94788  0.92655   -21.22123 1.000 16.68898  ? 377 ARG A O    1 
ATOM   5763 C CB   . ARG A 1 385 ? 10.58999  2.27359   -23.67715 1.000 17.62334  ? 377 ARG A CB   1 
ATOM   5764 C CG   . ARG A 1 385 ? 10.87884  3.00511   -24.98133 1.000 21.34681  ? 377 ARG A CG   1 
ATOM   5765 C CD   . ARG A 1 385 ? 10.41091  2.18758   -26.21658 1.000 18.90094  ? 377 ARG A CD   1 
ATOM   5766 N NE   . ARG A 1 385 ? 11.01508  0.86484   -26.22879 1.000 16.50944  ? 377 ARG A NE   1 
ATOM   5767 C CZ   . ARG A 1 385 ? 12.25422  0.60909   -26.62300 1.000 17.92597  ? 377 ARG A CZ   1 
ATOM   5768 N NH1  . ARG A 1 385 ? 13.02367  1.58787   -27.08413 1.000 23.17153  ? 377 ARG A NH1  1 
ATOM   5769 N NH2  . ARG A 1 385 ? 12.71808  -0.63479  -26.55339 1.000 19.13597  ? 377 ARG A NH2  1 
ATOM   5770 H H    . ARG A 1 385 ? 12.99362  2.33893   -22.94462 1.000 18.53926  ? 377 ARG A H    1 
ATOM   5771 H HA   . ARG A 1 385 ? 10.79144  3.82984   -22.40950 1.000 18.26671  ? 377 ARG A HA   1 
ATOM   5772 H HB2  . ARG A 1 385 ? 10.95485  1.37797   -23.75226 1.000 21.16503  ? 377 ARG A HB2  1 
ATOM   5773 H HB3  . ARG A 1 385 ? 9.62712   2.23145   -23.56760 1.000 21.16503  ? 377 ARG A HB3  1 
ATOM   5774 H HG2  . ARG A 1 385 ? 10.40920  3.85384   -24.98325 1.000 25.63320  ? 377 ARG A HG2  1 
ATOM   5775 H HG3  . ARG A 1 385 ? 11.83405  3.15433   -25.06004 1.000 25.63320  ? 377 ARG A HG3  1 
ATOM   5776 H HD2  . ARG A 1 385 ? 9.44684   2.08416   -26.18859 1.000 22.69816  ? 377 ARG A HD2  1 
ATOM   5777 H HD3  . ARG A 1 385 ? 10.67142  2.65124   -27.02779 1.000 22.69816  ? 377 ARG A HD3  1 
ATOM   5778 H HE   . ARG A 1 385 ? 10.53520  0.20299   -25.96181 1.000 19.82835  ? 377 ARG A HE   1 
ATOM   5779 H HH11 . ARG A 1 385 ? 12.71834  2.39066   -27.12768 1.000 27.82286  ? 377 ARG A HH11 1 
ATOM   5780 H HH12 . ARG A 1 385 ? 13.82742  1.41908   -27.33928 1.000 27.82286  ? 377 ARG A HH12 1 
ATOM   5781 H HH21 . ARG A 1 385 ? 12.21517  -1.26516  -26.25452 1.000 22.98019  ? 377 ARG A HH21 1 
ATOM   5782 H HH22 . ARG A 1 385 ? 13.52106  -0.80911  -26.80722 1.000 22.98019  ? 377 ARG A HH22 1 
ATOM   5783 N N    . PRO A 1 386 ? 10.65690  2.80734   -20.04123 1.000 15.29117  ? 378 PRO A N    1 
ATOM   5784 C CA   . PRO A 1 386 ? 10.73162  2.06783   -18.76535 1.000 16.38553  ? 378 PRO A CA   1 
ATOM   5785 C C    . PRO A 1 386 ? 9.66717   0.99736   -18.58245 1.000 16.55710  ? 378 PRO A C    1 
ATOM   5786 O O    . PRO A 1 386 ? 9.90160   0.05720   -17.80602 1.000 13.44453  ? 378 PRO A O    1 
ATOM   5787 C CB   . PRO A 1 386 ? 10.59012  3.16728   -17.70371 1.000 15.07989  ? 378 PRO A CB   1 
ATOM   5788 C CG   . PRO A 1 386 ? 9.94632   4.31855   -18.39611 1.000 22.49950  ? 378 PRO A CG   1 
ATOM   5789 C CD   . PRO A 1 386 ? 10.36042  4.23575   -19.84206 1.000 14.75894  ? 378 PRO A CD   1 
ATOM   5790 H HA   . PRO A 1 386 ? 11.60563  1.65316   -18.69427 1.000 19.67966  ? 378 PRO A HA   1 
ATOM   5791 H HB2  . PRO A 1 386 ? 10.03417  2.84891   -16.97539 1.000 18.11289  ? 378 PRO A HB2  1 
ATOM   5792 H HB3  . PRO A 1 386 ? 11.46665  3.41329   -17.36893 1.000 18.11289  ? 378 PRO A HB3  1 
ATOM   5793 H HG2  . PRO A 1 386 ? 8.98239   4.24914   -18.31299 1.000 27.01642  ? 378 PRO A HG2  1 
ATOM   5794 H HG3  . PRO A 1 386 ? 10.25454  5.14869   -18.00017 1.000 27.01642  ? 378 PRO A HG3  1 
ATOM   5795 H HD2  . PRO A 1 386 ? 9.63773   4.52063   -20.42298 1.000 17.72775  ? 378 PRO A HD2  1 
ATOM   5796 H HD3  . PRO A 1 386 ? 11.14942  4.77606   -20.00469 1.000 17.72775  ? 378 PRO A HD3  1 
ATOM   5797 N N    . TRP A 1 387 ? 8.51742   1.10801   -19.25429 1.000 15.73247  ? 379 TRP A N    1 
ATOM   5798 C CA   . TRP A 1 387 ? 7.38284   0.22528   -19.02568 1.000 13.52377  ? 379 TRP A CA   1 
ATOM   5799 C C    . TRP A 1 387 ? 7.31466   -0.92090  -20.02740 1.000 16.64968  ? 379 TRP A C    1 
ATOM   5800 O O    . TRP A 1 387 ? 6.27018   -1.57009  -20.14790 1.000 18.23655  ? 379 TRP A O    1 
ATOM   5801 C CB   . TRP A 1 387 ? 6.08909   1.04302   -19.04839 1.000 15.83588  ? 379 TRP A CB   1 
ATOM   5802 C CG   . TRP A 1 387 ? 6.09058   2.20428   -18.10761 1.000 16.76374  ? 379 TRP A CG   1 
ATOM   5803 C CD1  . TRP A 1 387 ? 6.34327   3.51382   -18.41626 1.000 22.49856  ? 379 TRP A CD1  1 
ATOM   5804 C CD2  . TRP A 1 387 ? 5.82413   2.17058   -16.70009 1.000 15.69634  ? 379 TRP A CD2  1 
ATOM   5805 N NE1  . TRP A 1 387 ? 6.25489   4.29267   -17.28816 1.000 20.55380  ? 379 TRP A NE1  1 
ATOM   5806 C CE2  . TRP A 1 387 ? 5.94078   3.49386   -16.22000 1.000 16.29005  ? 379 TRP A CE2  1 
ATOM   5807 C CE3  . TRP A 1 387 ? 5.51224   1.14993   -15.79747 1.000 15.05102  ? 379 TRP A CE3  1 
ATOM   5808 C CZ2  . TRP A 1 387 ? 5.74234   3.82439   -14.88020 1.000 17.76277  ? 379 TRP A CZ2  1 
ATOM   5809 C CZ3  . TRP A 1 387 ? 5.31297   1.47669   -14.47315 1.000 17.36374  ? 379 TRP A CZ3  1 
ATOM   5810 C CH2  . TRP A 1 387 ? 5.43346   2.80507   -14.02159 1.000 19.99543  ? 379 TRP A CH2  1 
ATOM   5811 H H    . TRP A 1 387 ? 8.37281   1.70146   -19.85969 1.000 18.89599  ? 379 TRP A H    1 
ATOM   5812 H HA   . TRP A 1 387 ? 7.47243   -0.17645  -18.14733 1.000 16.24555  ? 379 TRP A HA   1 
ATOM   5813 H HB2  . TRP A 1 387 ? 5.95504   1.38902   -19.94461 1.000 19.02007  ? 379 TRP A HB2  1 
ATOM   5814 H HB3  . TRP A 1 387 ? 5.35053   0.46435   -18.80226 1.000 19.02007  ? 379 TRP A HB3  1 
ATOM   5815 H HD1  . TRP A 1 387 ? 6.54559   3.83049   -19.26696 1.000 27.01529  ? 379 TRP A HD1  1 
ATOM   5816 H HE1  . TRP A 1 387 ? 6.37689   5.14342   -17.25731 1.000 24.68158  ? 379 TRP A HE1  1 
ATOM   5817 H HE3  . TRP A 1 387 ? 5.44060   0.26825   -16.08454 1.000 18.07824  ? 379 TRP A HE3  1 
ATOM   5818 H HZ2  . TRP A 1 387 ? 5.81690   4.70219   -14.58222 1.000 21.33235  ? 379 TRP A HZ2  1 
ATOM   5819 H HZ3  . TRP A 1 387 ? 5.09470   0.80680   -13.86611 1.000 20.85351  ? 379 TRP A HZ3  1 
ATOM   5820 H HH2  . TRP A 1 387 ? 5.30025   2.99342   -13.12066 1.000 24.01154  ? 379 TRP A HH2  1 
ATOM   5821 N N    . GLU A 1 388 ? 8.41238   -1.20308  -20.72117 1.000 15.19764  ? 380 GLU A N    1 
ATOM   5822 C CA   . GLU A 1 388 ? 8.46524   -2.30174  -21.66749 1.000 13.50603  ? 380 GLU A CA   1 
ATOM   5823 C C    . GLU A 1 388 ? 9.91119   -2.75442  -21.80317 1.000 16.99751  ? 380 GLU A C    1 
ATOM   5824 O O    . GLU A 1 388 ? 10.84051  -2.14743  -21.25318 1.000 18.33822  ? 380 GLU A O    1 
ATOM   5825 C CB   . GLU A 1 388 ? 7.87248   -1.89661  -23.02736 1.000 17.85171  ? 380 GLU A CB   1 
ATOM   5826 C CG   . GLU A 1 388 ? 8.57629   -0.75305  -23.68624 1.000 16.04850  ? 380 GLU A CG   1 
ATOM   5827 C CD   . GLU A 1 388 ? 8.00709   -0.40901  -25.06308 1.000 17.42384  ? 380 GLU A CD   1 
ATOM   5828 O OE1  . GLU A 1 388 ? 6.91106   0.18621   -25.12248 1.000 23.99917  ? 380 GLU A OE1  1 
ATOM   5829 O OE2  . GLU A 1 388 ? 8.67771   -0.72971  -26.07004 1.000 22.34335  ? 380 GLU A OE2  1 
ATOM   5830 H H    . GLU A 1 388 ? 9.14917   -0.76404  -20.65809 1.000 18.25419  ? 380 GLU A H    1 
ATOM   5831 H HA   . GLU A 1 388 ? 7.94782   -3.04877  -21.32819 1.000 16.22426  ? 380 GLU A HA   1 
ATOM   5832 H HB2  . GLU A 1 388 ? 7.92254   -2.65769  -23.62665 1.000 21.43907  ? 380 GLU A HB2  1 
ATOM   5833 H HB3  . GLU A 1 388 ? 6.94694   -1.63705  -22.89733 1.000 21.43907  ? 380 GLU A HB3  1 
ATOM   5834 H HG2  . GLU A 1 388 ? 8.49319   0.03322   -23.12429 1.000 19.27522  ? 380 GLU A HG2  1 
ATOM   5835 H HG3  . GLU A 1 388 ? 9.51191   -0.98266  -23.79928 1.000 19.27522  ? 380 GLU A HG3  1 
ATOM   5836 N N    . ALA A 1 389 ? 10.08822  -3.84533  -22.53603 1.000 16.84294  ? 381 ALA A N    1 
ATOM   5837 C CA   . ALA A 1 389 ? 11.42040  -4.38701  -22.74038 1.000 15.60405  ? 381 ALA A CA   1 
ATOM   5838 C C    . ALA A 1 389 ? 12.29427  -3.40753  -23.51512 1.000 17.52570  ? 381 ALA A C    1 
ATOM   5839 O O    . ALA A 1 389 ? 11.83619  -2.71105  -24.43179 1.000 15.23442  ? 381 ALA A O    1 
ATOM   5840 C CB   . ALA A 1 389 ? 11.35161  -5.72332  -23.48142 1.000 22.29552  ? 381 ALA A CB   1 
ATOM   5841 H H    . ALA A 1 389 ? 9.45857   -4.28601  -22.92196 1.000 20.22855  ? 381 ALA A H    1 
ATOM   5842 H HA   . ALA A 1 389 ? 11.83143  -4.54112  -21.87540 1.000 18.74188  ? 381 ALA A HA   1 
ATOM   5843 H HB1  . ALA A 1 389 ? 12.25271  -6.05525  -23.61836 1.000 26.77164  ? 381 ALA A HB1  1 
ATOM   5844 H HB2  . ALA A 1 389 ? 10.84410  -6.35461  -22.94775 1.000 26.77164  ? 381 ALA A HB2  1 
ATOM   5845 H HB3  . ALA A 1 389 ? 10.91541  -5.58781  -24.33715 1.000 26.77164  ? 381 ALA A HB3  1 
ATOM   5846 N N    . ASN A 1 390 ? 13.56705  -3.36926  -23.13326 1.000 15.80346  ? 382 ASN A N    1 
ATOM   5847 C CA   . ASN A 1 390 ? 14.59927  -2.61091  -23.82166 1.000 16.89224  ? 382 ASN A CA   1 
ATOM   5848 C C    . ASN A 1 390 ? 15.77695  -3.52991  -24.10947 1.000 20.38633  ? 382 ASN A C    1 
ATOM   5849 O O    . ASN A 1 390 ? 16.03808  -4.47731  -23.36648 1.000 18.14095  ? 382 ASN A O    1 
ATOM   5850 C CB   . ASN A 1 390 ? 15.10364  -1.41690  -23.00030 1.000 20.06771  ? 382 ASN A CB   1 
ATOM   5851 C CG   . ASN A 1 390 ? 14.05538  -0.36663  -22.79973 1.000 15.47310  ? 382 ASN A CG   1 
ATOM   5852 O OD1  . ASN A 1 390 ? 14.05176  0.66179   -23.48430 1.000 19.56489  ? 382 ASN A OD1  1 
ATOM   5853 N ND2  . ASN A 1 390 ? 13.13236  -0.62086  -21.86050 1.000 17.38950  ? 382 ASN A ND2  1 
ATOM   5854 H H    . ASN A 1 390 ? 13.86765  -3.79363  -22.44831 1.000 18.98118  ? 382 ASN A H    1 
ATOM   5855 H HA   . ASN A 1 390 ? 14.23289  -2.27034  -24.65273 1.000 20.28771  ? 382 ASN A HA   1 
ATOM   5856 H HB2  . ASN A 1 390 ? 15.38474  -1.73062  -22.12654 1.000 24.09828  ? 382 ASN A HB2  1 
ATOM   5857 H HB3  . ASN A 1 390 ? 15.85222  -1.00882  -23.46290 1.000 24.09828  ? 382 ASN A HB3  1 
ATOM   5858 H HD21 . ASN A 1 390 ? 12.50799  -0.05010  -21.70559 1.000 20.88443  ? 382 ASN A HD21 1 
ATOM   5859 H HD22 . ASN A 1 390 ? 13.16486  -1.35463  -21.41316 1.000 20.88443  ? 382 ASN A HD22 1 
ATOM   5860 N N    . THR A 1 391 ? 16.49207  -3.24870  -25.19637 1.000 17.93622  ? 383 THR A N    1 
ATOM   5861 C CA   . THR A 1 391 ? 17.66921  -4.02593  -25.57076 1.000 22.56554  ? 383 THR A CA   1 
ATOM   5862 C C    . THR A 1 391 ? 18.79491  -3.04747  -25.86790 1.000 22.53381  ? 383 THR A C    1 
ATOM   5863 O O    . THR A 1 391 ? 18.76883  -2.35979  -26.89304 1.000 24.02016  ? 383 THR A O    1 
ATOM   5864 C CB   . THR A 1 391 ? 17.39396  -4.92798  -26.77354 1.000 24.94214  ? 383 THR A CB   1 
ATOM   5865 O OG1  . THR A 1 391 ? 16.29067  -5.79753  -26.47926 1.000 24.43183  ? 383 THR A OG1  1 
ATOM   5866 C CG2  . THR A 1 391 ? 18.63220  -5.76394  -27.08251 1.000 25.60983  ? 383 THR A CG2  1 
ATOM   5867 H H    . THR A 1 391 ? 16.31231  -2.60522  -25.73787 1.000 21.54049  ? 383 THR A H    1 
ATOM   5868 H HA   . THR A 1 391 ? 17.93156  -4.59341  -24.82911 1.000 27.09567  ? 383 THR A HA   1 
ATOM   5869 H HB   . THR A 1 391 ? 17.17607  -4.39033  -27.55094 1.000 29.94759  ? 383 THR A HB   1 
ATOM   5870 H HG1  . THR A 1 391 ? 16.21652  -6.38071  -27.07927 1.000 29.33521  ? 383 THR A HG1  1 
ATOM   5871 H HG21 . THR A 1 391 ? 18.42611  -6.42284  -27.76388 1.000 30.74882  ? 383 THR A HG21 1 
ATOM   5872 H HG22 . THR A 1 391 ? 19.34692  -5.19208  -27.40353 1.000 30.74882  ? 383 THR A HG22 1 
ATOM   5873 H HG23 . THR A 1 391 ? 18.93138  -6.22225  -26.28166 1.000 30.74882  ? 383 THR A HG23 1 
ATOM   5874 N N    . LEU A 1 392 ? 19.76943  -2.97317  -24.96958 1.000 22.26199  ? 384 LEU A N    1 
ATOM   5875 C CA   . LEU A 1 392 ? 20.88811  -2.05764  -25.11259 1.000 20.50221  ? 384 LEU A CA   1 
ATOM   5876 C C    . LEU A 1 392 ? 22.16985  -2.81096  -25.44730 1.000 24.60040  ? 384 LEU A C    1 
ATOM   5877 O O    . LEU A 1 392 ? 22.36568  -3.95931  -25.04431 1.000 24.98967  ? 384 LEU A O    1 
ATOM   5878 C CB   . LEU A 1 392 ? 21.08316  -1.24681  -23.83175 1.000 20.70990  ? 384 LEU A CB   1 
ATOM   5879 C CG   . LEU A 1 392 ? 20.36259  0.09748   -23.76558 1.000 20.68560  ? 384 LEU A CG   1 
ATOM   5880 C CD1  . LEU A 1 392 ? 18.86738  -0.05298  -23.85170 1.000 32.96454  ? 384 LEU A CD1  1 
ATOM   5881 C CD2  . LEU A 1 392 ? 20.76175  0.83749   -22.48359 1.000 25.22552  ? 384 LEU A CD2  1 
ATOM   5882 H H    . LEU A 1 392 ? 19.80298  -3.45286  -24.25658 1.000 26.73141  ? 384 LEU A H    1 
ATOM   5883 H HA   . LEU A 1 392 ? 20.71038  -1.44765  -25.84554 1.000 24.61967  ? 384 LEU A HA   1 
ATOM   5884 H HB2  . LEU A 1 392 ? 20.76372  -1.77935  -23.08659 1.000 24.86891  ? 384 LEU A HB2  1 
ATOM   5885 H HB3  . LEU A 1 392 ? 22.03112  -1.06835  -23.72969 1.000 24.86891  ? 384 LEU A HB3  1 
ATOM   5886 H HG   . LEU A 1 392 ? 20.63010  0.62665   -24.53325 1.000 24.83974  ? 384 LEU A HG   1 
ATOM   5887 H HD11 . LEU A 1 392 ? 18.45516  0.81726   -23.73483 1.000 39.57447  ? 384 LEU A HD11 1 
ATOM   5888 H HD12 . LEU A 1 392 ? 18.63594  -0.41449  -24.72156 1.000 39.57447  ? 384 LEU A HD12 1 
ATOM   5889 H HD13 . LEU A 1 392 ? 18.56994  -0.65642  -23.15292 1.000 39.57447  ? 384 LEU A HD13 1 
ATOM   5890 H HD21 . LEU A 1 392 ? 20.24577  1.65624   -22.41789 1.000 30.28764  ? 384 LEU A HD21 1 
ATOM   5891 H HD22 . LEU A 1 392 ? 20.57761  0.26829   -21.72004 1.000 30.28764  ? 384 LEU A HD22 1 
ATOM   5892 H HD23 . LEU A 1 392 ? 21.70852  1.04522   -22.52063 1.000 30.28764  ? 384 LEU A HD23 1 
ATOM   5893 N N    . ASP A 1 393 ? 23.03237  -2.15781  -26.21675 1.000 27.02959  ? 385 ASP A N    1 
ATOM   5894 C CA   . ASP A 1 393 ? 24.37343  -2.65751  -26.45884 1.000 27.29539  ? 385 ASP A CA   1 
ATOM   5895 C C    . ASP A 1 393 ? 25.29500  -2.22859  -25.31920 1.000 22.18319  ? 385 ASP A C    1 
ATOM   5896 O O    . ASP A 1 393 ? 25.03066  -1.25912  -24.60504 1.000 22.87954  ? 385 ASP A O    1 
ATOM   5897 C CB   . ASP A 1 393 ? 24.89463  -2.13340  -27.79986 1.000 42.91277  ? 385 ASP A CB   1 
ATOM   5898 C CG   . ASP A 1 393 ? 25.98706  -3.00111  -28.38337 1.000 51.55813  ? 385 ASP A CG   1 
ATOM   5899 O OD1  . ASP A 1 393 ? 27.10427  -2.99517  -27.82445 1.000 55.29256  ? 385 ASP A OD1  1 
ATOM   5900 O OD2  . ASP A 1 393 ? 25.72977  -3.68532  -29.39915 1.000 57.04504  ? 385 ASP A OD2  1 
ATOM   5901 H H    . ASP A 1 393 ? 22.86096  -1.41443  -26.61375 1.000 32.45253  ? 385 ASP A H    1 
ATOM   5902 H HA   . ASP A 1 393 ? 24.37218  -3.62662  -26.50031 1.000 32.77149  ? 385 ASP A HA   1 
ATOM   5903 H HB2  . ASP A 1 393 ? 24.16188  -2.10644  -28.43489 1.000 51.51234  ? 385 ASP A HB2  1 
ATOM   5904 H HB3  . ASP A 1 393 ? 25.25578  -1.24226  -27.67199 1.000 51.51234  ? 385 ASP A HB3  1 
ATOM   5905 N N    . VAL A 1 394 ? 26.40335  -2.95437  -25.16536 1.000 33.00783  ? 386 VAL A N    1 
ATOM   5906 C CA   . VAL A 1 394 ? 27.38797  -2.57393  -24.15739 1.000 26.81464  ? 386 VAL A CA   1 
ATOM   5907 C C    . VAL A 1 394 ? 27.88351  -1.15509  -24.40106 1.000 30.50291  ? 386 VAL A C    1 
ATOM   5908 O O    . VAL A 1 394 ? 28.23484  -0.44107  -23.45327 1.000 31.52050  ? 386 VAL A O    1 
ATOM   5909 C CB   . VAL A 1 394 ? 28.55460  -3.58180  -24.13940 1.000 37.37113  ? 386 VAL A CB   1 
ATOM   5910 C CG1  . VAL A 1 394 ? 28.05498  -4.96861  -23.77395 1.000 42.39306  ? 386 VAL A CG1  1 
ATOM   5911 C CG2  . VAL A 1 394 ? 29.26433  -3.60305  -25.49074 1.000 45.74638  ? 386 VAL A CG2  1 
ATOM   5912 H H    . VAL A 1 394 ? 26.60347  -3.65521  -25.62184 1.000 39.62642  ? 386 VAL A H    1 
ATOM   5913 H HA   . VAL A 1 394 ? 26.96050  -2.59764  -23.28698 1.000 32.19460  ? 386 VAL A HA   1 
ATOM   5914 H HB   . VAL A 1 394 ? 29.19639  -3.30603  -23.46637 1.000 44.86238  ? 386 VAL A HB   1 
ATOM   5915 H HG11 . VAL A 1 394 ? 28.81151  -5.57356  -23.72299 1.000 50.88869  ? 386 VAL A HG11 1 
ATOM   5916 H HG12 . VAL A 1 394 ? 27.60664  -4.92653  -22.91482 1.000 50.88869  ? 386 VAL A HG12 1 
ATOM   5917 H HG13 . VAL A 1 394 ? 27.43512  -5.27088  -24.45608 1.000 50.88869  ? 386 VAL A HG13 1 
ATOM   5918 H HG21 . VAL A 1 394 ? 29.98537  -4.25110  -25.45859 1.000 54.91268  ? 386 VAL A HG21 1 
ATOM   5919 H HG22 . VAL A 1 394 ? 28.62684  -3.85134  -26.17838 1.000 54.91268  ? 386 VAL A HG22 1 
ATOM   5920 H HG23 . VAL A 1 394 ? 29.62126  -2.71990  -25.67391 1.000 54.91268  ? 386 VAL A HG23 1 
ATOM   5921 N N    . ASP A 1 395 ? 27.91333  -0.71703  -25.66425 1.000 29.35691  ? 387 ASP A N    1 
ATOM   5922 C CA   . ASP A 1 395 ? 28.32490  0.64536   -25.98737 1.000 29.06134  ? 387 ASP A CA   1 
ATOM   5923 C C    . ASP A 1 395 ? 27.29563  1.69048   -25.58211 1.000 31.45061  ? 387 ASP A C    1 
ATOM   5924 O O    . ASP A 1 395 ? 27.59999  2.88666   -25.62881 1.000 27.41641  ? 387 ASP A O    1 
ATOM   5925 C CB   . ASP A 1 395 ? 28.59189  0.77854   -27.49071 1.000 29.50768  ? 387 ASP A CB   1 
ATOM   5926 C CG   . ASP A 1 395 ? 29.73573  -0.08322  -27.95425 1.000 49.20861  ? 387 ASP A CG   1 
ATOM   5927 O OD1  . ASP A 1 395 ? 29.64549  -0.66853  -29.05538 1.000 62.58163  ? 387 ASP A OD1  1 
ATOM   5928 O OD2  . ASP A 1 395 ? 30.72972  -0.17955  -27.20709 1.000 38.20408  ? 387 ASP A OD2  1 
ATOM   5929 H H    . ASP A 1 395 ? 27.69954  -1.19131  -26.34905 1.000 35.24532  ? 387 ASP A H    1 
ATOM   5930 H HA   . ASP A 1 395 ? 29.14968  0.82645   -25.51004 1.000 34.89063  ? 387 ASP A HA   1 
ATOM   5931 H HB2  . ASP A 1 395 ? 27.79721  0.51093   -27.97833 1.000 35.42624  ? 387 ASP A HB2  1 
ATOM   5932 H HB3  . ASP A 1 395 ? 28.81004  1.70180   -27.69296 1.000 35.42624  ? 387 ASP A HB3  1 
ATOM   5933 N N    . ASP A 1 396 ? 26.08808  1.28041   -25.21350 1.000 25.83652  ? 388 ASP A N    1 
ATOM   5934 C CA   . ASP A 1 396 ? 25.05330  2.20728   -24.78922 1.000 23.71070  ? 388 ASP A CA   1 
ATOM   5935 C C    . ASP A 1 396 ? 25.15215  2.55099   -23.30549 1.000 22.28602  ? 388 ASP A C    1 
ATOM   5936 O O    . ASP A 1 396 ? 24.26735  3.23377   -22.78003 1.000 26.12652  ? 388 ASP A O    1 
ATOM   5937 C CB   . ASP A 1 396 ? 23.66928  1.61925   -25.08701 1.000 25.40504  ? 388 ASP A CB   1 
ATOM   5938 C CG   . ASP A 1 396 ? 23.39554  1.47882   -26.57054 1.000 30.50217  ? 388 ASP A CG   1 
ATOM   5939 O OD1  . ASP A 1 396 ? 23.86421  2.34023   -27.35090 1.000 29.14367  ? 388 ASP A OD1  1 
ATOM   5940 O OD2  . ASP A 1 396 ? 22.70290  0.50847   -26.95681 1.000 31.51877  ? 388 ASP A OD2  1 
ATOM   5941 H H    . ASP A 1 396 ? 25.84250  0.45631   -25.20135 1.000 31.02084  ? 388 ASP A H    1 
ATOM   5942 H HA   . ASP A 1 396 ? 25.14667  3.02883   -25.29641 1.000 28.46986  ? 388 ASP A HA   1 
ATOM   5943 H HB2  . ASP A 1 396 ? 23.60800  0.73791   -24.68652 1.000 30.50308  ? 388 ASP A HB2  1 
ATOM   5944 H HB3  . ASP A 1 396 ? 22.99117  2.20226   -24.71131 1.000 30.50308  ? 388 ASP A HB3  1 
ATOM   5945 N N    . ILE A 1 397 ? 26.19640  2.08620   -22.62592 1.000 23.75704  ? 389 ILE A N    1 
ATOM   5946 C CA   . ILE A 1 397 ? 26.38135  2.29551   -21.19353 1.000 27.39061  ? 389 ILE A CA   1 
ATOM   5947 C C    . ILE A 1 397 ? 27.50986  3.29595   -20.98293 1.000 28.00201  ? 389 ILE A C    1 
ATOM   5948 O O    . ILE A 1 397 ? 28.60357  3.13145   -21.53527 1.000 29.70943  ? 389 ILE A O    1 
ATOM   5949 C CB   . ILE A 1 397 ? 26.69940  0.97545   -20.47088 1.000 22.60277  ? 389 ILE A CB   1 
ATOM   5950 C CG1  . ILE A 1 397 ? 25.63626  -0.08270  -20.77167 1.000 24.01649  ? 389 ILE A CG1  1 
ATOM   5951 C CG2  . ILE A 1 397 ? 26.83176  1.21304   -18.96929 1.000 31.68759  ? 389 ILE A CG2  1 
ATOM   5952 C CD1  . ILE A 1 397 ? 24.23591  0.33720   -20.42116 1.000 29.77377  ? 389 ILE A CD1  1 
ATOM   5953 H H    . ILE A 1 397 ? 26.83178  1.63159   -22.98539 1.000 28.52547  ? 389 ILE A H    1 
ATOM   5954 H HA   . ILE A 1 397 ? 25.56568  2.67016   -20.82581 1.000 32.88576  ? 389 ILE A HA   1 
ATOM   5955 H HB   . ILE A 1 397 ? 27.54721  0.64196   -20.80391 1.000 27.14034  ? 389 ILE A HB   1 
ATOM   5956 H HG12 . ILE A 1 397 ? 25.65543  -0.28111  -21.72097 1.000 28.83681  ? 389 ILE A HG12 1 
ATOM   5957 H HG13 . ILE A 1 397 ? 25.84057  -0.88199  -20.26149 1.000 28.83681  ? 389 ILE A HG13 1 
ATOM   5958 H HG21 . ILE A 1 397 ? 26.90730  0.35693   -18.51955 1.000 38.04213  ? 389 ILE A HG21 1 
ATOM   5959 H HG22 . ILE A 1 397 ? 27.62525  1.74544   -18.80253 1.000 38.04213  ? 389 ILE A HG22 1 
ATOM   5960 H HG23 . ILE A 1 397 ? 26.04488  1.68425   -18.65355 1.000 38.04213  ? 389 ILE A HG23 1 
ATOM   5961 H HD11 . ILE A 1 397 ? 23.63529  -0.40942  -20.57184 1.000 35.74554  ? 389 ILE A HD11 1 
ATOM   5962 H HD12 . ILE A 1 397 ? 24.20930  0.59999   -19.48781 1.000 35.74554  ? 389 ILE A HD12 1 
ATOM   5963 H HD13 . ILE A 1 397 ? 23.98068  1.08564   -20.98293 1.000 35.74554  ? 389 ILE A HD13 1 
ATOM   5964 N N    . ASN A 1 398 ? 27.24618  4.32374   -20.17803 1.000 26.61899  ? 390 ASN A N    1 
ATOM   5965 C CA   . ASN A 1 398 ? 28.25100  5.29599   -19.75982 1.000 27.00415  ? 390 ASN A CA   1 
ATOM   5966 C C    . ASN A 1 398 ? 28.59574  5.00145   -18.30355 1.000 31.69880  ? 390 ASN A C    1 
ATOM   5967 O O    . ASN A 1 398 ? 27.73747  5.12490   -17.42460 1.000 26.47212  ? 390 ASN A O    1 
ATOM   5968 C CB   . ASN A 1 398 ? 27.73457  6.72185   -19.93277 1.000 39.86285  ? 390 ASN A CB   1 
ATOM   5969 C CG   . ASN A 1 398 ? 28.79054  7.76797   -19.61803 1.000 45.11944  ? 390 ASN A CG   1 
ATOM   5970 O OD1  . ASN A 1 398 ? 29.92533  7.44026   -19.27593 1.000 60.26349  ? 390 ASN A OD1  1 
ATOM   5971 N ND2  . ASN A 1 398 ? 28.41711  9.03582   -19.73138 1.000 50.04858  ? 390 ASN A ND2  1 
ATOM   5972 H H    . ASN A 1 398 ? 26.46659  4.48257   -19.85150 1.000 31.95982  ? 390 ASN A H    1 
ATOM   5973 H HA   . ASN A 1 398 ? 29.05211  5.20015   -20.29829 1.000 32.42201  ? 390 ASN A HA   1 
ATOM   5974 H HB2  . ASN A 1 398 ? 27.45224  6.84701   -20.85230 1.000 47.85244  ? 390 ASN A HB2  1 
ATOM   5975 H HB3  . ASN A 1 398 ? 26.98478  6.86192   -19.33352 1.000 47.85244  ? 390 ASN A HB3  1 
ATOM   5976 H HD21 . ASN A 1 398 ? 27.61406  9.22769   -19.97198 1.000 60.07532  ? 390 ASN A HD21 1 
ATOM   5977 H HD22 . ASN A 1 398 ? 28.97808  9.66590   -19.56427 1.000 60.07532  ? 390 ASN A HD22 1 
ATOM   5978 N N    . TYR A 1 399 ? 29.83800  4.58444   -18.05413 1.000 28.87355  ? 391 TYR A N    1 
ATOM   5979 C CA   . TYR A 1 399 ? 30.31758  4.28703   -16.70213 1.000 28.46382  ? 391 TYR A CA   1 
ATOM   5980 C C    . TYR A 1 399 ? 30.84382  5.58624   -16.11270 1.000 42.49518  ? 391 TYR A C    1 
ATOM   5981 O O    . TYR A 1 399 ? 31.97272  5.99493   -16.39126 1.000 37.37893  ? 391 TYR A O    1 
ATOM   5982 C CB   . TYR A 1 399 ? 31.38704  3.19990   -16.73281 1.000 35.73052  ? 391 TYR A CB   1 
ATOM   5983 C CG   . TYR A 1 399 ? 30.87199  1.87922   -17.26031 1.000 37.89578  ? 391 TYR A CG   1 
ATOM   5984 C CD1  . TYR A 1 399 ? 30.36881  0.91525   -16.40001 1.000 42.76142  ? 391 TYR A CD1  1 
ATOM   5985 C CD2  . TYR A 1 399 ? 30.88040  1.60193   -18.62140 1.000 36.66031  ? 391 TYR A CD2  1 
ATOM   5986 C CE1  . TYR A 1 399 ? 29.88454  -0.28965  -16.87934 1.000 41.46968  ? 391 TYR A CE1  1 
ATOM   5987 C CE2  . TYR A 1 399 ? 30.40176  0.39737   -19.11233 1.000 49.36331  ? 391 TYR A CE2  1 
ATOM   5988 C CZ   . TYR A 1 399 ? 29.90557  -0.54396  -18.23693 1.000 47.76938  ? 391 TYR A CZ   1 
ATOM   5989 O OH   . TYR A 1 399 ? 29.42724  -1.74283  -18.71717 1.000 49.61475  ? 391 TYR A OH   1 
ATOM   5990 H H    . TYR A 1 399 ? 30.43353  4.46363   -18.66269 1.000 34.66529  ? 391 TYR A H    1 
ATOM   5991 H HA   . TYR A 1 399 ? 29.58577  3.96621   -16.15219 1.000 34.17361  ? 391 TYR A HA   1 
ATOM   5992 H HB2  . TYR A 1 399 ? 32.11332  3.48889   -17.30718 1.000 42.89365  ? 391 TYR A HB2  1 
ATOM   5993 H HB3  . TYR A 1 399 ? 31.71453  3.05494   -15.83135 1.000 42.89365  ? 391 TYR A HB3  1 
ATOM   5994 H HD1  . TYR A 1 399 ? 30.35646  1.08110   -15.48501 1.000 51.33073  ? 391 TYR A HD1  1 
ATOM   5995 H HD2  . TYR A 1 399 ? 31.21340  2.23633   -19.21431 1.000 44.00939  ? 391 TYR A HD2  1 
ATOM   5996 H HE1  . TYR A 1 399 ? 29.54662  -0.92494  -16.29019 1.000 49.78064  ? 391 TYR A HE1  1 
ATOM   5997 H HE2  . TYR A 1 399 ? 30.41540  0.22566   -20.02624 1.000 59.25300  ? 391 TYR A HE2  1 
ATOM   5998 H HH   . TYR A 1 399 ? 29.03151  -2.16021  -18.10497 1.000 59.55472  ? 391 TYR A HH   1 
ATOM   5999 N N    . VAL A 1 400 ? 30.02020  6.24338   -15.29164 1.000 31.62208  ? 392 VAL A N    1 
ATOM   6000 C CA   . VAL A 1 400 ? 30.30739  7.61894   -14.89524 1.000 26.70743  ? 392 VAL A CA   1 
ATOM   6001 C C    . VAL A 1 400 ? 31.05642  7.73985   -13.57472 1.000 36.16422  ? 392 VAL A C    1 
ATOM   6002 O O    . VAL A 1 400 ? 31.53486  8.83783   -13.24601 1.000 34.73166  ? 392 VAL A O    1 
ATOM   6003 C CB   . VAL A 1 400 ? 29.01132  8.44355   -14.78646 1.000 26.23758  ? 392 VAL A CB   1 
ATOM   6004 C CG1  . VAL A 1 400 ? 28.29489  8.49866   -16.11913 1.000 35.45608  ? 392 VAL A CG1  1 
ATOM   6005 C CG2  . VAL A 1 400 ? 28.09398  7.86004   -13.69727 1.000 31.29873  ? 392 VAL A CG2  1 
ATOM   6006 H H    . VAL A 1 400 ? 29.29873  5.91697   -14.95618 1.000 37.96352  ? 392 VAL A H    1 
ATOM   6007 H HA   . VAL A 1 400 ? 30.87354  7.99068   -15.58964 1.000 32.06594  ? 392 VAL A HA   1 
ATOM   6008 H HB   . VAL A 1 400 ? 29.23997  9.35219   -14.53549 1.000 31.50212  ? 392 VAL A HB   1 
ATOM   6009 H HG11 . VAL A 1 400 ? 27.49676  9.04207   -16.02638 1.000 42.56432  ? 392 VAL A HG11 1 
ATOM   6010 H HG12 . VAL A 1 400 ? 28.88695  8.89059   -16.78000 1.000 42.56432  ? 392 VAL A HG12 1 
ATOM   6011 H HG13 . VAL A 1 400 ? 28.05263  7.59779   -16.38493 1.000 42.56432  ? 392 VAL A HG13 1 
ATOM   6012 H HG21 . VAL A 1 400 ? 27.26989  8.37101   -13.67139 1.000 37.57550  ? 392 VAL A HG21 1 
ATOM   6013 H HG22 . VAL A 1 400 ? 27.90197  6.93318   -13.90933 1.000 37.57550  ? 392 VAL A HG22 1 
ATOM   6014 H HG23 . VAL A 1 400 ? 28.54536  7.91669   -12.84056 1.000 37.57550  ? 392 VAL A HG23 1 
ATOM   6015 N N    . GLY A 1 401 ? 31.16616  6.66919   -12.79950 1.000 32.80033  ? 393 GLY A N    1 
ATOM   6016 C CA   . GLY A 1 401 ? 31.86625  6.76811   -11.53651 1.000 36.84613  ? 393 GLY A CA   1 
ATOM   6017 C C    . GLY A 1 401 ? 31.75929  5.49174   -10.72915 1.000 42.58245  ? 393 GLY A C    1 
ATOM   6018 O O    . GLY A 1 401 ? 31.28537  4.45812   -11.20796 1.000 32.51427  ? 393 GLY A O    1 
ATOM   6019 H H    . GLY A 1 401 ? 30.84910  5.89079   -12.98162 1.000 39.37741  ? 393 GLY A H    1 
ATOM   6020 H HA2  . GLY A 1 401 ? 32.80483  6.95002   -11.70045 1.000 44.23237  ? 393 GLY A HA2  1 
ATOM   6021 H HA3  . GLY A 1 401 ? 31.49036  7.49410   -11.01444 1.000 44.23237  ? 393 GLY A HA3  1 
ATOM   6022 N N    . THR A 1 402 ? 32.21348  5.59660   -9.48215  1.000 24.03215  ? 394 THR A N    1 
ATOM   6023 C CA   . THR A 1 402 ? 32.33345  4.44342   -8.60559  1.000 30.91345  ? 394 THR A CA   1 
ATOM   6024 C C    . THR A 1 402 ? 32.04035  4.86711   -7.17374  1.000 47.88131  ? 394 THR A C    1 
ATOM   6025 O O    . THR A 1 402 ? 32.52746  5.90777   -6.72549  1.000 42.17457  ? 394 THR A O    1 
ATOM   6026 C CB   . THR A 1 402 ? 33.73788  3.83819   -8.70393  1.000 39.21209  ? 394 THR A CB   1 
ATOM   6027 O OG1  . THR A 1 402 ? 33.99268  3.42431   -10.05413 1.000 47.04769  ? 394 THR A OG1  1 
ATOM   6028 C CG2  . THR A 1 402 ? 33.87593  2.65034   -7.77276  1.000 42.18210  ? 394 THR A CG2  1 
ATOM   6029 H H    . THR A 1 402 ? 32.46086  6.33593   -9.11909  1.000 28.85560  ? 394 THR A H    1 
ATOM   6030 H HA   . THR A 1 402 ? 31.68105  3.77144   -8.85802  1.000 37.11316  ? 394 THR A HA   1 
ATOM   6031 H HB   . THR A 1 402 ? 34.39420  4.50335   -8.44373  1.000 47.07153  ? 394 THR A HB   1 
ATOM   6032 H HG1  . THR A 1 402 ? 34.77802  3.13415   -10.12232 1.000 56.47425  ? 394 THR A HG1  1 
ATOM   6033 H HG21 . THR A 1 402 ? 34.73947  2.22737   -7.90037  1.000 50.63554  ? 394 THR A HG21 1 
ATOM   6034 H HG22 . THR A 1 402 ? 33.80115  2.94134   -6.85047  1.000 50.63554  ? 394 THR A HG22 1 
ATOM   6035 H HG23 . THR A 1 402 ? 33.17782  2.00229   -7.95597  1.000 50.63554  ? 394 THR A HG23 1 
ATOM   6036 N N    . ILE A 1 403 ? 31.23482  4.07247   -6.47179  1.000 30.91344  ? 395 ILE A N    1 
ATOM   6037 C CA   . ILE A 1 403 ? 31.07185  4.18236   -5.02499  1.000 22.34227  ? 395 ILE A CA   1 
ATOM   6038 C C    . ILE A 1 403 ? 31.90131  3.04781   -4.43826  1.000 26.80844  ? 395 ILE A C    1 
ATOM   6039 O O    . ILE A 1 403 ? 31.45282  1.90055   -4.37795  1.000 30.83931  ? 395 ILE A O    1 
ATOM   6040 C CB   . ILE A 1 403 ? 29.60120  4.11037   -4.59539  1.000 22.34466  ? 395 ILE A CB   1 
ATOM   6041 C CG1  . ILE A 1 403 ? 28.78420  5.17908   -5.32742  1.000 26.68059  ? 395 ILE A CG1  1 
ATOM   6042 C CG2  . ILE A 1 403 ? 29.48453  4.30467   -3.08729  1.000 21.55777  ? 395 ILE A CG2  1 
ATOM   6043 C CD1  . ILE A 1 403 ? 27.31012  5.24003   -4.91693  1.000 22.07222  ? 395 ILE A CD1  1 
ATOM   6044 H H    . ILE A 1 403 ? 30.76036  3.44615   -6.82139  1.000 37.11316  ? 395 ILE A H    1 
ATOM   6045 H HA   . ILE A 1 403 ? 31.41990  5.03251   -4.71351  1.000 26.82774  ? 395 ILE A HA   1 
ATOM   6046 H HB   . ILE A 1 403 ? 29.25365  3.23538   -4.82883  1.000 26.83061  ? 395 ILE A HB   1 
ATOM   6047 H HG12 . ILE A 1 403 ? 29.17583  6.04737   -5.14414  1.000 32.03373  ? 395 ILE A HG12 1 
ATOM   6048 H HG13 . ILE A 1 403 ? 28.81622  4.99494   -6.27925  1.000 32.03373  ? 395 ILE A HG13 1 
ATOM   6049 H HG21 . ILE A 1 403 ? 28.56754  4.13945   -2.81760  1.000 25.88634  ? 395 ILE A HG21 1 
ATOM   6050 H HG22 . ILE A 1 403 ? 30.07804  3.68019   -2.64157  1.000 25.88634  ? 395 ILE A HG22 1 
ATOM   6051 H HG23 . ILE A 1 403 ? 29.73553  5.21509   -2.86583  1.000 25.88634  ? 395 ILE A HG23 1 
ATOM   6052 H HD11 . ILE A 1 403 ? 26.83665  5.82773   -5.52630  1.000 26.50369  ? 395 ILE A HD11 1 
ATOM   6053 H HD12 . ILE A 1 403 ? 26.93344  4.34714   -4.95886  1.000 26.50369  ? 395 ILE A HD12 1 
ATOM   6054 H HD13 . ILE A 1 403 ? 27.24831  5.58294   -4.01166  1.000 26.50369  ? 395 ILE A HD13 1 
ATOM   6055 N N    . GLY A 1 404 ? 33.12618  3.35969   -4.02143  1.000 27.09890  ? 396 GLY A N    1 
ATOM   6056 C CA   . GLY A 1 404 ? 34.02487  2.32672   -3.55628  1.000 31.95736  ? 396 GLY A CA   1 
ATOM   6057 C C    . GLY A 1 404 ? 33.57347  1.71506   -2.24714  1.000 21.32332  ? 396 GLY A C    1 
ATOM   6058 O O    . GLY A 1 404 ? 32.74341  2.25870   -1.51355  1.000 26.65965  ? 396 GLY A O    1 
ATOM   6059 H H    . GLY A 1 404 ? 33.45187  4.15536   -4.00059  1.000 32.53571  ? 396 GLY A H    1 
ATOM   6060 H HA2  . GLY A 1 404 ? 34.07566  1.62229   -4.22119  1.000 38.36586  ? 396 GLY A HA2  1 
ATOM   6061 H HA3  . GLY A 1 404 ? 34.90907  2.70445   -3.42821  1.000 38.36586  ? 396 GLY A HA3  1 
ATOM   6062 N N    . TYR A 1 405 ? 34.13915  0.54872   -1.94381  1.000 23.45654  ? 397 TYR A N    1 
ATOM   6063 C CA   . TYR A 1 405 ? 33.79840  -0.10295  -0.68684  1.000 22.38199  ? 397 TYR A CA   1 
ATOM   6064 C C    . TYR A 1 405 ? 34.55977  0.50574   0.48666   1.000 27.67273  ? 397 TYR A C    1 
ATOM   6065 O O    . TYR A 1 405 ? 33.95944  1.04359   1.42261   1.000 22.25803  ? 397 TYR A O    1 
ATOM   6066 C CB   . TYR A 1 405 ? 34.08578  -1.60079  -0.74940  1.000 20.65774  ? 397 TYR A CB   1 
ATOM   6067 C CG   . TYR A 1 405 ? 33.80584  -2.25709  0.57179   1.000 28.75374  ? 397 TYR A CG   1 
ATOM   6068 C CD1  . TYR A 1 405 ? 32.49979  -2.53503  0.96641   1.000 22.11284  ? 397 TYR A CD1  1 
ATOM   6069 C CD2  . TYR A 1 405 ? 34.83429  -2.56244  1.44875   1.000 25.15652  ? 397 TYR A CD2  1 
ATOM   6070 C CE1  . TYR A 1 405 ? 32.23238  -3.11373  2.18375   1.000 23.02092  ? 397 TYR A CE1  1 
ATOM   6071 C CE2  . TYR A 1 405 ? 34.57531  -3.14766  2.66857   1.000 26.83393  ? 397 TYR A CE2  1 
ATOM   6072 C CZ   . TYR A 1 405 ? 33.26956  -3.41250  3.03385   1.000 24.24197  ? 397 TYR A CZ   1 
ATOM   6073 O OH   . TYR A 1 405 ? 33.00015  -3.97848  4.24800   1.000 28.48114  ? 397 TYR A OH   1 
ATOM   6074 H H    . TYR A 1 405 ? 34.70597  0.12804   -2.43507  1.000 28.16488  ? 397 TYR A H    1 
ATOM   6075 H HA   . TYR A 1 405 ? 32.84672  0.02169   -0.54662  1.000 26.87541  ? 397 TYR A HA   1 
ATOM   6076 H HB2  . TYR A 1 405 ? 33.51980  -2.01002  -1.42253  1.000 24.80631  ? 397 TYR A HB2  1 
ATOM   6077 H HB3  . TYR A 1 405 ? 35.01960  -1.74113  -0.97117  1.000 24.80631  ? 397 TYR A HB3  1 
ATOM   6078 H HD1  . TYR A 1 405 ? 31.79588  -2.32528  0.39595   1.000 26.55243  ? 397 TYR A HD1  1 
ATOM   6079 H HD2  . TYR A 1 405 ? 35.71225  -2.36944  1.21032   1.000 30.20485  ? 397 TYR A HD2  1 
ATOM   6080 H HE1  . TYR A 1 405 ? 31.35563  -3.30179  2.43043   1.000 27.64213  ? 397 TYR A HE1  1 
ATOM   6081 H HE2  . TYR A 1 405 ? 35.27479  -3.36305  3.24237   1.000 32.21774  ? 397 TYR A HE2  1 
ATOM   6082 H HH   . TYR A 1 405 ? 33.70662  -4.04362  4.69773   1.000 34.19439  ? 397 TYR A HH   1 
ATOM   6083 N N    . ALA A 1 406 ? 35.89059  0.40455   0.46128   1.000 27.81374  ? 398 ALA A N    1 
ATOM   6084 C CA   . ALA A 1 406 ? 36.68120  0.78676   1.62913   1.000 25.45001  ? 398 ALA A CA   1 
ATOM   6085 C C    . ALA A 1 406 ? 36.38851  2.21704   2.05300   1.000 16.95579  ? 398 ALA A C    1 
ATOM   6086 O O    . ALA A 1 406 ? 36.30282  2.51280   3.25108   1.000 28.96854  ? 398 ALA A O    1 
ATOM   6087 C CB   . ALA A 1 406 ? 38.17306  0.61751   1.33625   1.000 30.51778  ? 398 ALA A CB   1 
ATOM   6088 H H    . ALA A 1 406 ? 36.35124  0.12257   -0.20796  1.000 33.39351  ? 398 ALA A H    1 
ATOM   6089 H HA   . ALA A 1 406 ? 36.44720  0.19846   2.36400   1.000 30.55703  ? 398 ALA A HA   1 
ATOM   6090 H HB1  . ALA A 1 406 ? 38.67959  0.85869   2.12755   1.000 36.63835  ? 398 ALA A HB1  1 
ATOM   6091 H HB2  . ALA A 1 406 ? 38.34594  -0.30781  1.10215   1.000 36.63835  ? 398 ALA A HB2  1 
ATOM   6092 H HB3  . ALA A 1 406 ? 38.41761  1.19681   0.59766   1.000 36.63835  ? 398 ALA A HB3  1 
ATOM   6093 N N    . GLU A 1 407 ? 36.22330  3.11742   1.08460   1.000 22.29305  ? 399 GLU A N    1 
ATOM   6094 C CA   . GLU A 1 407 ? 36.05520  4.53167   1.39036   1.000 26.44044  ? 399 GLU A CA   1 
ATOM   6095 C C    . GLU A 1 407 ? 34.72472  4.83105   2.06496   1.000 28.53411  ? 399 GLU A C    1 
ATOM   6096 O O    . GLU A 1 407 ? 34.57297  5.90287   2.66022   1.000 27.30037  ? 399 GLU A O    1 
ATOM   6097 C CB   . GLU A 1 407 ? 36.15502  5.36384   0.10825   1.000 34.03025  ? 399 GLU A CB   1 
ATOM   6098 C CG   . GLU A 1 407 ? 37.41105  5.12590   -0.70404  1.000 64.79172  ? 399 GLU A CG   1 
ATOM   6099 C CD   . GLU A 1 407 ? 37.18212  4.19263   -1.87655  1.000 65.82313  ? 399 GLU A CD   1 
ATOM   6100 O OE1  . GLU A 1 407 ? 37.27840  4.65282   -3.03525  1.000 89.51913  ? 399 GLU A OE1  1 
ATOM   6101 O OE2  . GLU A 1 407 ? 36.91144  2.99593   -1.63625  1.000 44.37764  ? 399 GLU A OE2  1 
ATOM   6102 H H    . GLU A 1 407 ? 36.20512  2.93360   0.24467   1.000 26.76868  ? 399 GLU A H    1 
ATOM   6103 H HA   . GLU A 1 407 ? 36.76975  4.79481   1.99126   1.000 31.74555  ? 399 GLU A HA   1 
ATOM   6104 H HB2  . GLU A 1 407 ? 35.39645  5.15059   -0.45743  1.000 40.85333  ? 399 GLU A HB2  1 
ATOM   6105 H HB3  . GLU A 1 407 ? 36.13601  6.30345   0.34842   1.000 40.85333  ? 399 GLU A HB3  1 
ATOM   6106 H HG2  . GLU A 1 407 ? 37.72746  5.97391   -1.05283  1.000 77.76709  ? 399 GLU A HG2  1 
ATOM   6107 H HG3  . GLU A 1 407 ? 38.08695  4.72934   -0.13238  1.000 77.76709  ? 399 GLU A HG3  1 
ATOM   6108 N N    . ASN A 1 408 ? 33.75423  3.92350   1.98137   1.000 24.21888  ? 400 ASN A N    1 
ATOM   6109 C CA   . ASN A 1 408 ? 32.39727  4.22366   2.42010   1.000 22.69701  ? 400 ASN A CA   1 
ATOM   6110 C C    . ASN A 1 408 ? 31.91040  3.29862   3.52783   1.000 23.91625  ? 400 ASN A C    1 
ATOM   6111 O O    . ASN A 1 408 ? 30.74489  3.39602   3.93324   1.000 20.98079  ? 400 ASN A O    1 
ATOM   6112 C CB   . ASN A 1 408 ? 31.44479  4.17756   1.21755   1.000 21.75882  ? 400 ASN A CB   1 
ATOM   6113 C CG   . ASN A 1 408 ? 31.69700  5.30694   0.23476   1.000 26.33580  ? 400 ASN A CG   1 
ATOM   6114 O OD1  . ASN A 1 408 ? 31.46839  6.46612   0.54789   1.000 22.19544  ? 400 ASN A OD1  1 
ATOM   6115 N ND2  . ASN A 1 408 ? 32.18504  4.96985   -0.95727  1.000 30.68381  ? 400 ASN A ND2  1 
ATOM   6116 H H    . ASN A 1 408 ? 33.85895  3.12725   1.67376   1.000 29.07967  ? 400 ASN A H    1 
ATOM   6117 H HA   . ASN A 1 408 ? 32.37808  5.12242   2.78445   1.000 27.25343  ? 400 ASN A HA   1 
ATOM   6118 H HB2  . ASN A 1 408 ? 31.56638  3.33725   0.74850   1.000 26.12761  ? 400 ASN A HB2  1 
ATOM   6119 H HB3  . ASN A 1 408 ? 30.53076  4.25180   1.53369   1.000 26.12761  ? 400 ASN A HB3  1 
ATOM   6120 H HD21 . ASN A 1 408 ? 32.34299  5.57770   -1.54478  1.000 36.83759  ? 400 ASN A HD21 1 
ATOM   6121 H HD22 . ASN A 1 408 ? 32.34231  4.14427   -1.13971  1.000 36.83759  ? 400 ASN A HD22 1 
ATOM   6122 N N    . VAL A 1 409 ? 32.77213  2.42445   4.04995   1.000 20.67359  ? 401 VAL A N    1 
ATOM   6123 C CA   . VAL A 1 409 ? 32.41365  1.63614   5.22004   1.000 19.51788  ? 401 VAL A CA   1 
ATOM   6124 C C    . VAL A 1 409 ? 32.32410  2.54508   6.43680   1.000 29.23569  ? 401 VAL A C    1 
ATOM   6125 O O    . VAL A 1 409 ? 33.19592  3.39301   6.66165   1.000 24.87685  ? 401 VAL A O    1 
ATOM   6126 C CB   . VAL A 1 409 ? 33.44365  0.51935   5.44845   1.000 25.03221  ? 401 VAL A CB   1 
ATOM   6127 C CG1  . VAL A 1 409 ? 33.14130  -0.22128  6.74299   1.000 35.49100  ? 401 VAL A CG1  1 
ATOM   6128 C CG2  . VAL A 1 409 ? 33.44624  -0.42106  4.27315   1.000 28.00826  ? 401 VAL A CG2  1 
ATOM   6129 H H    . VAL A 1 409 ? 33.56218  2.27301   3.74583   1.000 24.82533  ? 401 VAL A H    1 
ATOM   6130 H HA   . VAL A 1 409 ? 31.54649  1.22766   5.07145   1.000 23.43848  ? 401 VAL A HA   1 
ATOM   6131 H HB   . VAL A 1 409 ? 34.32992  0.90514   5.52958   1.000 30.05567  ? 401 VAL A HB   1 
ATOM   6132 H HG11 . VAL A 1 409 ? 33.68766  -1.02173  6.78388   1.000 42.60622  ? 401 VAL A HG11 1 
ATOM   6133 H HG12 . VAL A 1 409 ? 33.34648  0.35794   7.49353   1.000 42.60622  ? 401 VAL A HG12 1 
ATOM   6134 H HG13 . VAL A 1 409 ? 32.20154  -0.46115  6.75751   1.000 42.60622  ? 401 VAL A HG13 1 
ATOM   6135 H HG21 . VAL A 1 409 ? 34.19513  -1.03157  4.35884   1.000 33.62694  ? 401 VAL A HG21 1 
ATOM   6136 H HG22 . VAL A 1 409 ? 32.61342  -0.91829  4.26471   1.000 33.62694  ? 401 VAL A HG22 1 
ATOM   6137 H HG23 . VAL A 1 409 ? 33.53180  0.09477   3.45614   1.000 33.62694  ? 401 VAL A HG23 1 
ATOM   6138 N N    . THR A 1 410 ? 31.27774  2.36056   7.24146   1.000 21.64746  ? 402 THR A N    1 
ATOM   6139 C CA   . THR A 1 410 ? 31.08319  3.17512   8.43269   1.000 22.64235  ? 402 THR A CA   1 
ATOM   6140 C C    . THR A 1 410 ? 31.91592  2.63806   9.59650   1.000 29.45311  ? 402 THR A C    1 
ATOM   6141 O O    . THR A 1 410 ? 32.27978  1.46014   9.64821   1.000 28.93878  ? 402 THR A O    1 
ATOM   6142 C CB   . THR A 1 410 ? 29.60060  3.22176   8.81471   1.000 25.02538  ? 402 THR A CB   1 
ATOM   6143 O OG1  . THR A 1 410 ? 29.14092  1.90535   9.14332   1.000 28.79908  ? 402 THR A OG1  1 
ATOM   6144 C CG2  . THR A 1 410 ? 28.77413  3.76488   7.65415   1.000 27.42749  ? 402 THR A CG2  1 
ATOM   6145 H H    . THR A 1 410 ? 30.66670  1.76835   7.11688   1.000 25.99398  ? 402 THR A H    1 
ATOM   6146 H HA   . THR A 1 410 ? 31.37411  4.08288   8.25317   1.000 27.18784  ? 402 THR A HA   1 
ATOM   6147 H HB   . THR A 1 410 ? 29.48313  3.80338   9.58206   1.000 30.04747  ? 402 THR A HB   1 
ATOM   6148 H HG1  . THR A 1 410 ? 29.48743  1.65194   9.86535   1.000 34.57592  ? 402 THR A HG1  1 
ATOM   6149 H HG21 . THR A 1 410 ? 27.84176  3.83134   7.91334   1.000 32.93001  ? 402 THR A HG21 1 
ATOM   6150 H HG22 . THR A 1 410 ? 29.09434  4.64515   7.40219   1.000 32.93001  ? 402 THR A HG22 1 
ATOM   6151 H HG23 . THR A 1 410 ? 28.84681  3.17265   6.88937   1.000 32.93001  ? 402 THR A HG23 1 
ATOM   6152 N N    . HIS A 1 411 ? 32.21072  3.52703   10.54280  1.000 31.47236  ? 403 HIS A N    1 
ATOM   6153 C CA   . HIS A 1 411 ? 33.11017  3.18587   11.63842  1.000 41.68839  ? 403 HIS A CA   1 
ATOM   6154 C C    . HIS A 1 411 ? 32.61304  1.96387   12.40347  1.000 54.75582  ? 403 HIS A C    1 
ATOM   6155 O O    . HIS A 1 411 ? 31.43749  1.87749   12.77322  1.000 47.68803  ? 403 HIS A O    1 
ATOM   6156 C CB   . HIS A 1 411 ? 33.25178  4.37423   12.58751  1.000 64.01251  ? 403 HIS A CB   1 
ATOM   6157 C CG   . HIS A 1 411 ? 34.17571  4.12025   13.73837  1.000 77.16024  ? 403 HIS A CG   1 
ATOM   6158 N ND1  . HIS A 1 411 ? 33.72392  3.80583   15.00247  1.000 75.53436  ? 403 HIS A ND1  1 
ATOM   6159 C CD2  . HIS A 1 411 ? 35.52734  4.13411   13.81521  1.000 66.38377  ? 403 HIS A CD2  1 
ATOM   6160 C CE1  . HIS A 1 411 ? 34.75732  3.63821   15.80816  1.000 72.76302  ? 403 HIS A CE1  1 
ATOM   6161 N NE2  . HIS A 1 411 ? 35.86330  3.83122   15.11230  1.000 86.54601  ? 403 HIS A NE2  1 
ATOM   6162 H H    . HIS A 1 411 ? 31.90427  4.33003   10.57247  1.000 37.78386  ? 403 HIS A H    1 
ATOM   6163 H HA   . HIS A 1 411 ? 33.98207  2.97315   11.27040  1.000 50.04309  ? 403 HIS A HA   1 
ATOM   6164 H HB2  . HIS A 1 411 ? 33.59947  5.13094   12.09011  1.000 76.83204  ? 403 HIS A HB2  1 
ATOM   6165 H HB3  . HIS A 1 411 ? 32.37841  4.58905   12.95081  1.000 76.83204  ? 403 HIS A HB3  1 
ATOM   6166 H HD2  . HIS A 1 411 ? 36.11790  4.31488   13.11990  1.000 79.67754  ? 403 HIS A HD2  1 
ATOM   6167 H HE1  . HIS A 1 411 ? 34.71356  3.42127   16.71145  1.000 87.33265  ? 403 HIS A HE1  1 
ATOM   6168 N N    . GLY A 1 412 ? 33.52245  1.02035   12.64857  1.000 46.00662  ? 404 GLY A N    1 
ATOM   6169 C CA   . GLY A 1 412 ? 33.20791  -0.18033  13.39296  1.000 40.40759  ? 404 GLY A CA   1 
ATOM   6170 C C    . GLY A 1 412 ? 32.53821  -1.28182  12.60071  1.000 62.36307  ? 404 GLY A C    1 
ATOM   6171 O O    . GLY A 1 412 ? 32.26387  -2.34805  13.16835  1.000 47.97878  ? 404 GLY A O    1 
ATOM   6172 N N    . SER A 1 413 ? 32.27023  -1.07035  11.31382  1.000 41.24341  ? 405 SER A N    1 
ATOM   6173 C CA   . SER A 1 413 ? 31.55603  -2.04752  10.50249  1.000 45.88515  ? 405 SER A CA   1 
ATOM   6174 C C    . SER A 1 413 ? 32.53421  -3.03036  9.87180   1.000 51.72146  ? 405 SER A C    1 
ATOM   6175 O O    . SER A 1 413 ? 33.48479  -2.62540  9.19555   1.000 47.27147  ? 405 SER A O    1 
ATOM   6176 C CB   . SER A 1 413 ? 30.73403  -1.34795  9.42040   1.000 29.36879  ? 405 SER A CB   1 
ATOM   6177 O OG   . SER A 1 413 ? 29.79840  -0.45626  10.01067  1.000 42.19569  ? 405 SER A OG   1 
ATOM   6178 N N    . ALA A 1 414 ? 32.29520  -4.31698  10.09661  1.000 64.97224  ? 406 ALA A N    1 
ATOM   6179 C CA   . ALA A 1 414 ? 33.12356  -5.37903  9.54389   1.000 60.99717  ? 406 ALA A CA   1 
ATOM   6180 C C    . ALA A 1 414 ? 32.21956  -6.56540  9.22893   1.000 60.20375  ? 406 ALA A C    1 
ATOM   6181 O O    . ALA A 1 414 ? 31.13126  -6.68025  9.79048   1.000 50.56123  ? 406 ALA A O    1 
ATOM   6182 C CB   . ALA A 1 414 ? 34.23183  -5.79470  10.51875  1.000 51.06864  ? 406 ALA A CB   1 
ATOM   6183 N N    . PRO A 1 415 ? 32.65502  -7.45642  8.33459   1.000 69.74161  ? 407 PRO A N    1 
ATOM   6184 C CA   . PRO A 1 415 ? 31.82059  -8.63774  8.04164   1.000 61.38096  ? 407 PRO A CA   1 
ATOM   6185 C C    . PRO A 1 415 ? 31.56835  -9.50202  9.26104   1.000 69.51604  ? 407 PRO A C    1 
ATOM   6186 O O    . PRO A 1 415 ? 30.65812  -10.33815 9.23067   1.000 56.00323  ? 407 PRO A O    1 
ATOM   6187 C CB   . PRO A 1 415 ? 32.63315  -9.38885  6.97763   1.000 44.83603  ? 407 PRO A CB   1 
ATOM   6188 C CG   . PRO A 1 415 ? 34.04667  -8.93646  7.19821   1.000 71.94547  ? 407 PRO A CG   1 
ATOM   6189 C CD   . PRO A 1 415 ? 33.94870  -7.50191  7.63969   1.000 62.10177  ? 407 PRO A CD   1 
ATOM   6190 N N    . GLN A 1 416 ? 32.33338  -9.30897  10.34004  1.000 70.29840  ? 408 GLN A N    1 
ATOM   6191 C CA   . GLN A 1 416 ? 32.17714  -10.11949 11.54176  1.000 57.49219  ? 408 GLN A CA   1 
ATOM   6192 C C    . GLN A 1 416 ? 30.99324  -9.69121  12.39165  1.000 44.25275  ? 408 GLN A C    1 
ATOM   6193 O O    . GLN A 1 416 ? 30.60163  -10.43647 13.29898  1.000 40.72326  ? 408 GLN A O    1 
ATOM   6194 C CB   . GLN A 1 416 ? 33.47060  -10.07276 12.37398  1.000 70.18346  ? 408 GLN A CB   1 
ATOM   6195 C CG   . GLN A 1 416 ? 34.74362  -10.30565 11.55093  1.000 92.28793  ? 408 GLN A CG   1 
ATOM   6196 C CD   . GLN A 1 416 ? 34.63405  -11.47707 10.59068  1.000 96.42515  ? 408 GLN A CD   1 
ATOM   6197 O OE1  . GLN A 1 416 ? 33.67294  -11.58984 9.82820   1.000 79.40424  ? 408 GLN A OE1  1 
ATOM   6198 N NE2  . GLN A 1 416 ? 35.62344  -12.36097 10.62925  1.000 78.47429  ? 408 GLN A NE2  1 
ATOM   6199 N N    . VAL A 1 417 ? 30.43343  -8.50476  12.15439  1.000 41.29481  ? 409 VAL A N    1 
ATOM   6200 C CA   . VAL A 1 417 ? 29.40970  -8.02095  13.06927  1.000 32.58280  ? 409 VAL A CA   1 
ATOM   6201 C C    . VAL A 1 417 ? 28.05119  -8.65715  12.77867  1.000 34.41647  ? 409 VAL A C    1 
ATOM   6202 O O    . VAL A 1 417 ? 27.23586  -8.81452  13.69512  1.000 41.69329  ? 409 VAL A O    1 
ATOM   6203 C CB   . VAL A 1 417 ? 29.32410  -6.48408  13.02748  1.000 42.82842  ? 409 VAL A CB   1 
ATOM   6204 C CG1  . VAL A 1 417 ? 30.67910  -5.87549  13.35046  1.000 60.44706  ? 409 VAL A CG1  1 
ATOM   6205 C CG2  . VAL A 1 417 ? 28.81960  -6.00165  11.66662  1.000 56.84955  ? 409 VAL A CG2  1 
ATOM   6206 H HA   . VAL A 1 417 ? 29.66988  -8.28197  13.96653  1.000 39.11638  ? 409 VAL A HA   1 
ATOM   6207 H HB   . VAL A 1 417 ? 28.68824  -6.18638  13.69678  1.000 51.41113  ? 409 VAL A HB   1 
ATOM   6208 H HG11 . VAL A 1 417 ? 30.63747  -4.91724  13.20581  1.000 72.55349  ? 409 VAL A HG11 1 
ATOM   6209 H HG12 . VAL A 1 417 ? 30.89568  -6.06096  14.27760  1.000 72.55349  ? 409 VAL A HG12 1 
ATOM   6210 H HG13 . VAL A 1 417 ? 31.34865  -6.26897  12.76927  1.000 72.55349  ? 409 VAL A HG13 1 
ATOM   6211 H HG21 . VAL A 1 417 ? 28.22943  -5.24337  11.79930  1.000 68.23648  ? 409 VAL A HG21 1 
ATOM   6212 H HG22 . VAL A 1 417 ? 29.57899  -5.73870  11.12340  1.000 68.23648  ? 409 VAL A HG22 1 
ATOM   6213 H HG23 . VAL A 1 417 ? 28.33788  -6.72404  11.23419  1.000 68.23648  ? 409 VAL A HG23 1 
ATOM   6214 N N    . LEU A 1 418 ? 27.76216  -9.00339  11.51892  1.000 27.37210  ? 410 LEU A N    1 
ATOM   6215 C CA   . LEU A 1 418 ? 26.45027  -9.56320  11.20329  1.000 24.47431  ? 410 LEU A CA   1 
ATOM   6216 C C    . LEU A 1 418 ? 26.20731  -10.83778 11.99467  1.000 20.27865  ? 410 LEU A C    1 
ATOM   6217 O O    . LEU A 1 418 ? 25.14479  -11.01023 12.60531  1.000 21.31384  ? 410 LEU A O    1 
ATOM   6218 C CB   . LEU A 1 418 ? 26.32242  -9.83369  9.70522   1.000 25.60085  ? 410 LEU A CB   1 
ATOM   6219 C CG   . LEU A 1 418 ? 24.97436  -10.43667 9.28416   1.000 20.81352  ? 410 LEU A CG   1 
ATOM   6220 C CD1  . LEU A 1 418 ? 23.84444  -9.44613  9.56647   1.000 33.37441  ? 410 LEU A CD1  1 
ATOM   6221 C CD2  . LEU A 1 418 ? 25.00439  -10.84641 7.82532   1.000 36.34394  ? 410 LEU A CD2  1 
ATOM   6222 H H    . LEU A 1 418 ? 28.29534  -8.92541  10.84867  1.000 32.86354  ? 410 LEU A H    1 
ATOM   6223 H HA   . LEU A 1 418 ? 25.77231  -8.91195  11.44232  1.000 29.38619  ? 410 LEU A HA   1 
ATOM   6224 H HB2  . LEU A 1 418 ? 26.43139  -8.99541  9.22951   1.000 30.73804  ? 410 LEU A HB2  1 
ATOM   6225 H HB3  . LEU A 1 418 ? 27.01824  -10.45668 9.44327   1.000 30.73804  ? 410 LEU A HB3  1 
ATOM   6226 H HG   . LEU A 1 418 ? 24.80092  -11.23793 9.80262   1.000 24.99325  ? 410 LEU A HG   1 
ATOM   6227 H HD11 . LEU A 1 418 ? 23.00727  -9.82517  9.25600   1.000 40.06631  ? 410 LEU A HD11 1 
ATOM   6228 H HD12 . LEU A 1 418 ? 23.79936  -9.28228  10.52146  1.000 40.06631  ? 410 LEU A HD12 1 
ATOM   6229 H HD13 . LEU A 1 418 ? 24.02652  -8.61714  9.09686   1.000 40.06631  ? 410 LEU A HD13 1 
ATOM   6230 H HD21 . LEU A 1 418 ? 24.11736  -11.13597 7.56030   1.000 43.62975  ? 410 LEU A HD21 1 
ATOM   6231 H HD22 . LEU A 1 418 ? 25.27796  -10.08572 7.28921   1.000 43.62975  ? 410 LEU A HD22 1 
ATOM   6232 H HD23 . LEU A 1 418 ? 25.63662  -11.57367 7.71451   1.000 43.62975  ? 410 LEU A HD23 1 
ATOM   6233 N N    . SER A 1 419 ? 27.18980  -11.74919 11.98599  1.000 22.71158  ? 411 SER A N    1 
ATOM   6234 C CA   . SER A 1 419 ? 27.10592  -12.96578 12.78559  1.000 27.58639  ? 411 SER A CA   1 
ATOM   6235 C C    . SER A 1 419 ? 26.76197  -12.64205 14.23265  1.000 21.24462  ? 411 SER A C    1 
ATOM   6236 O O    . SER A 1 419 ? 25.88355  -13.26942 14.83287  1.000 23.46547  ? 411 SER A O    1 
ATOM   6237 C CB   . SER A 1 419 ? 28.43465  -13.73027 12.70912  1.000 28.09122  ? 411 SER A CB   1 
ATOM   6238 O OG   . SER A 1 419 ? 29.53264  -12.84386 12.86777  1.000 40.45508  ? 411 SER A OG   1 
ATOM   6239 H H    . SER A 1 419 ? 27.91250  -11.68242 11.52464  1.000 27.27092  ? 411 SER A H    1 
ATOM   6240 H HA   . SER A 1 419 ? 26.40676  -13.53351 12.42537  1.000 33.12069  ? 411 SER A HA   1 
ATOM   6241 H HB2  . SER A 1 419 ? 28.45903  -14.39399 13.41608  1.000 33.72649  ? 411 SER A HB2  1 
ATOM   6242 H HB3  . SER A 1 419 ? 28.50072  -14.16429 11.84416  1.000 33.72649  ? 411 SER A HB3  1 
ATOM   6243 H HG   . SER A 1 419 ? 30.25479  -13.27117 12.82890  1.000 48.56312  ? 411 SER A HG   1 
ATOM   6244 N N    . GLU A 1 420 ? 27.46105  -11.66779 14.81323  1.000 22.35679  ? 412 GLU A N    1 
ATOM   6245 C CA   . GLU A 1 420 ? 27.23229  -11.32922 16.21149  1.000 22.27663  ? 412 GLU A CA   1 
ATOM   6246 C C    . GLU A 1 420 ? 25.87262  -10.67365 16.40860  1.000 24.41467  ? 412 GLU A C    1 
ATOM   6247 O O    . GLU A 1 420 ? 25.22679  -10.89061 17.44017  1.000 24.23812  ? 412 GLU A O    1 
ATOM   6248 C CB   . GLU A 1 420 ? 28.34221  -10.41303 16.71445  1.000 35.66712  ? 412 GLU A CB   1 
ATOM   6249 C CG   . GLU A 1 420 ? 29.73067  -11.01109 16.57961  1.000 47.43471  ? 412 GLU A CG   1 
ATOM   6250 C CD   . GLU A 1 420 ? 30.82629  -10.05643 17.01566  1.000 58.70162  ? 412 GLU A CD   1 
ATOM   6251 O OE1  . GLU A 1 420 ? 30.68855  -8.83869  16.77780  1.000 46.55710  ? 412 GLU A OE1  1 
ATOM   6252 O OE2  . GLU A 1 420 ? 31.82787  -10.52644 17.59546  1.000 71.45674  ? 412 GLU A OE2  1 
ATOM   6253 H H    . GLU A 1 420 ? 28.06481  -11.19505 14.42388  1.000 26.84517  ? 412 GLU A H    1 
ATOM   6254 H HA   . GLU A 1 420 ? 27.25378  -12.14193 16.74059  1.000 26.74898  ? 412 GLU A HA   1 
ATOM   6255 H HB2  . GLU A 1 420 ? 28.32292  -9.58895  16.20316  1.000 42.81757  ? 412 GLU A HB2  1 
ATOM   6256 H HB3  . GLU A 1 420 ? 28.19011  -10.22436 17.65369  1.000 42.81757  ? 412 GLU A HB3  1 
ATOM   6257 H HG2  . GLU A 1 420 ? 29.78759  -11.80572 17.13297  1.000 56.93867  ? 412 GLU A HG2  1 
ATOM   6258 H HG3  . GLU A 1 420 ? 29.88643  -11.24199 15.65046  1.000 56.93867  ? 412 GLU A HG3  1 
ATOM   6259 N N    . LYS A 1 421 ? 25.40532  -9.90498  15.42148  1.000 22.25258  ? 413 LYS A N    1 
ATOM   6260 C CA   . LYS A 1 421 ? 24.09569  -9.26643  15.54749  1.000 20.58459  ? 413 LYS A CA   1 
ATOM   6261 C C    . LYS A 1 421 ? 22.96596  -10.28809 15.46992  1.000 19.32199  ? 413 LYS A C    1 
ATOM   6262 O O    . LYS A 1 421 ? 21.98666  -10.20274 16.22559  1.000 18.89884  ? 413 LYS A O    1 
ATOM   6263 C CB   . LYS A 1 421 ? 23.92418  -8.19743  14.46901  1.000 21.06597  ? 413 LYS A CB   1 
ATOM   6264 C CG   . LYS A 1 421 ? 22.88668  -7.13942  14.83368  1.000 20.89170  ? 413 LYS A CG   1 
ATOM   6265 C CD   . LYS A 1 421 ? 22.70198  -6.12909  13.71641  1.000 24.65578  ? 413 LYS A CD   1 
ATOM   6266 C CE   . LYS A 1 421 ? 22.11601  -4.83479  14.24067  1.000 30.73071  ? 413 LYS A CE   1 
ATOM   6267 N NZ   . LYS A 1 421 ? 23.07524  -4.08157  15.11336  1.000 28.99511  ? 413 LYS A NZ   1 
ATOM   6268 H H    . LYS A 1 421 ? 25.81788  -9.74098  14.68493  1.000 26.72012  ? 413 LYS A H    1 
ATOM   6269 H HA   . LYS A 1 421 ? 24.04755  -8.83171  16.41328  1.000 24.71853  ? 413 LYS A HA   1 
ATOM   6270 H HB2  . LYS A 1 421 ? 24.77346  -7.74888  14.33327  1.000 25.29618  ? 413 LYS A HB2  1 
ATOM   6271 H HB3  . LYS A 1 421 ? 23.63916  -8.62429  13.64594  1.000 25.29618  ? 413 LYS A HB3  1 
ATOM   6272 H HG2  . LYS A 1 421 ? 22.03338  -7.57022  14.99860  1.000 25.08707  ? 413 LYS A HG2  1 
ATOM   6273 H HG3  . LYS A 1 421 ? 23.17779  -6.66494  15.62805  1.000 25.08707  ? 413 LYS A HG3  1 
ATOM   6274 H HD2  . LYS A 1 421 ? 23.56199  -5.93433  13.31225  1.000 29.60396  ? 413 LYS A HD2  1 
ATOM   6275 H HD3  . LYS A 1 421 ? 22.09694  -6.49159  13.05051  1.000 29.60396  ? 413 LYS A HD3  1 
ATOM   6276 H HE2  . LYS A 1 421 ? 21.88163  -4.26602  13.49069  1.000 36.89387  ? 413 LYS A HE2  1 
ATOM   6277 H HE3  . LYS A 1 421 ? 21.32510  -5.03437  14.76558  1.000 36.89387  ? 413 LYS A HE3  1 
ATOM   6278 H HZ1  . LYS A 1 421 ? 22.74892  -3.27453  15.29858  1.000 34.81116  ? 413 LYS A HZ1  1 
ATOM   6279 H HZ2  . LYS A 1 421 ? 23.20431  -4.52281  15.87543  1.000 34.81116  ? 413 LYS A HZ2  1 
ATOM   6280 H HZ3  . LYS A 1 421 ? 23.85660  -3.98871  14.69747  1.000 34.81116  ? 413 LYS A HZ3  1 
ATOM   6281 N N    . ILE A 1 422 ? 23.06376  -11.24925 14.55193  1.000 16.06347  ? 414 ILE A N    1 
ATOM   6282 C CA   . ILE A 1 422 ? 22.03642  -12.27923 14.47915  1.000 15.32316  ? 414 ILE A CA   1 
ATOM   6283 C C    . ILE A 1 422 ? 22.01871  -13.08984 15.76864  1.000 15.16867  ? 414 ILE A C    1 
ATOM   6284 O O    . ILE A 1 422 ? 20.95129  -13.40953 16.30637  1.000 17.63328  ? 414 ILE A O    1 
ATOM   6285 C CB   . ILE A 1 422 ? 22.24995  -13.16585 13.23804  1.000 16.43236  ? 414 ILE A CB   1 
ATOM   6286 C CG1  . ILE A 1 422 ? 22.07257  -12.32865 11.96916  1.000 22.69471  ? 414 ILE A CG1  1 
ATOM   6287 C CG2  . ILE A 1 422 ? 21.28684  -14.33149 13.25470  1.000 22.59526  ? 414 ILE A CG2  1 
ATOM   6288 C CD1  . ILE A 1 422 ? 22.46143  -13.05269 10.67702  1.000 24.47916  ? 414 ILE A CD1  1 
ATOM   6289 H H    . ILE A 1 422 ? 23.69828  -11.32385 13.97625  1.000 19.29319  ? 414 ILE A H    1 
ATOM   6290 H HA   . ILE A 1 422 ? 21.17035  -11.85295 14.38371  1.000 18.40481  ? 414 ILE A HA   1 
ATOM   6291 H HB   . ILE A 1 422 ? 23.15298  -13.51973 13.25236  1.000 19.73586  ? 414 ILE A HB   1 
ATOM   6292 H HG12 . ILE A 1 422 ? 21.13960  -12.07411 11.89388  1.000 27.25067  ? 414 ILE A HG12 1 
ATOM   6293 H HG13 . ILE A 1 422 ? 22.62785  -11.53652 12.04053  1.000 27.25067  ? 414 ILE A HG13 1 
ATOM   6294 H HG21 . ILE A 1 422 ? 21.36638  -14.81882 12.41978  1.000 27.13134  ? 414 ILE A HG21 1 
ATOM   6295 H HG22 . ILE A 1 422 ? 21.50739  -14.91276 13.99927  1.000 27.13134  ? 414 ILE A HG22 1 
ATOM   6296 H HG23 . ILE A 1 422 ? 20.38334  -13.99321 13.35548  1.000 27.13134  ? 414 ILE A HG23 1 
ATOM   6297 H HD11 . ILE A 1 422 ? 22.40174  -12.42987 9.93579   1.000 29.39201  ? 414 ILE A HD11 1 
ATOM   6298 H HD12 . ILE A 1 422 ? 23.37020  -13.38146 10.76046  1.000 29.39201  ? 414 ILE A HD12 1 
ATOM   6299 H HD13 . ILE A 1 422 ? 21.85293  -13.79470 10.53540  1.000 29.39201  ? 414 ILE A HD13 1 
ATOM   6300 N N    . GLN A 1 423 ? 23.20173  -13.43195 16.29054  1.000 19.25117  ? 415 GLN A N    1 
ATOM   6301 C CA   . GLN A 1 423 ? 23.25766  -14.18940 17.53784  1.000 21.22012  ? 415 GLN A CA   1 
ATOM   6302 C C    . GLN A 1 423 ? 22.64804  -13.39840 18.69145  1.000 17.58963  ? 415 GLN A C    1 
ATOM   6303 O O    . GLN A 1 423 ? 21.86190  -13.93937 19.48130  1.000 22.29220  ? 415 GLN A O    1 
ATOM   6304 C CB   . GLN A 1 423 ? 24.70501  -14.57194 17.85073  1.000 24.12299  ? 415 GLN A CB   1 
ATOM   6305 C CG   . GLN A 1 423 ? 25.29103  -15.60165 16.90348  1.000 45.81738  ? 415 GLN A CG   1 
ATOM   6306 C CD   . GLN A 1 423 ? 26.73048  -15.94801 17.23815  1.000 67.16133  ? 415 GLN A CD   1 
ATOM   6307 O OE1  . GLN A 1 423 ? 27.61474  -15.86811 16.38362  1.000 65.98694  ? 415 GLN A OE1  1 
ATOM   6308 N NE2  . GLN A 1 423 ? 26.97264  -16.33598 18.48737  1.000 62.20117  ? 415 GLN A NE2  1 
ATOM   6309 H H    . GLN A 1 423 ? 23.96730  -13.24113 15.94838  1.000 23.11843  ? 415 GLN A H    1 
ATOM   6310 H HA   . GLN A 1 423 ? 22.74638  -15.00704 17.43317  1.000 25.48116  ? 415 GLN A HA   1 
ATOM   6311 H HB2  . GLN A 1 423 ? 25.25545  -13.77504 17.79718  1.000 28.96461  ? 415 GLN A HB2  1 
ATOM   6312 H HB3  . GLN A 1 423 ? 24.74194  -14.94105 18.74700  1.000 28.96461  ? 415 GLN A HB3  1 
ATOM   6313 H HG2  . GLN A 1 423 ? 24.76585  -16.41550 16.95583  1.000 54.99787  ? 415 GLN A HG2  1 
ATOM   6314 H HG3  . GLN A 1 423 ? 25.26860  -15.24989 15.99978  1.000 54.99787  ? 415 GLN A HG3  1 
ATOM   6315 H HE21 . GLN A 1 423 ? 26.32929  -16.37980 19.05639  1.000 74.65843  ? 415 GLN A HE21 1 
ATOM   6316 H HE22 . GLN A 1 423 ? 27.77254  -16.54299 18.72592  1.000 74.65843  ? 415 GLN A HE22 1 
ATOM   6317 N N    . GLN A 1 424 ? 22.98219  -12.10701 18.78540  1.000 20.05602  ? 416 GLN A N    1 
ATOM   6318 C CA   . GLN A 1 424 ? 22.40937  -11.25253 19.81876  1.000 22.02804  ? 416 GLN A CA   1 
ATOM   6319 C C    . GLN A 1 424 ? 20.89347  -11.19021 19.69619  1.000 23.03555  ? 416 GLN A C    1 
ATOM   6320 O O    . GLN A 1 424 ? 20.17596  -11.24080 20.70124  1.000 20.37416  ? 416 GLN A O    1 
ATOM   6321 C CB   . GLN A 1 424 ? 23.01150  -9.85144  19.72207  1.000 20.69402  ? 416 GLN A CB   1 
ATOM   6322 C CG   . GLN A 1 424 ? 22.56008  -8.88383  20.81375  1.000 33.68464  ? 416 GLN A CG   1 
ATOM   6323 C CD   . GLN A 1 424 ? 22.76528  -7.41643  20.43289  1.000 37.25384  ? 416 GLN A CD   1 
ATOM   6324 O OE1  . GLN A 1 424 ? 23.24343  -7.10326  19.34449  1.000 34.06469  ? 416 GLN A OE1  1 
ATOM   6325 N NE2  . GLN A 1 424 ? 22.40235  -6.51410  21.33750  1.000 35.02736  ? 416 GLN A NE2  1 
ATOM   6326 H H    . GLN A 1 424 ? 23.53611  -11.70597 18.26392  1.000 24.08425  ? 416 GLN A H    1 
ATOM   6327 H HA   . GLN A 1 424 ? 22.62742  -11.61761 20.69058  1.000 26.45067  ? 416 GLN A HA   1 
ATOM   6328 H HB2  . GLN A 1 424 ? 23.97685  -9.92665  19.77985  1.000 24.84985  ? 416 GLN A HB2  1 
ATOM   6329 H HB3  . GLN A 1 424 ? 22.75925  -9.46628  18.86830  1.000 24.84985  ? 416 GLN A HB3  1 
ATOM   6330 H HG2  . GLN A 1 424 ? 21.61478  -9.01925  20.98393  1.000 40.43859  ? 416 GLN A HG2  1 
ATOM   6331 H HG3  . GLN A 1 424 ? 23.07057  -9.05773  21.62001  1.000 40.43859  ? 416 GLN A HG3  1 
ATOM   6332 H HE21 . GLN A 1 424 ? 22.07205  -6.76818  22.08979  1.000 42.04986  ? 416 GLN A HE21 1 
ATOM   6333 H HE22 . GLN A 1 424 ? 22.49768  -5.67579  21.17092  1.000 42.04986  ? 416 GLN A HE22 1 
ATOM   6334 N N    . TYR A 1 425 ? 20.38830  -11.10144 18.46647  1.000 15.89829  ? 417 TYR A N    1 
ATOM   6335 C CA   . TYR A 1 425 ? 18.94588  -11.04859 18.26088  1.000 14.95580  ? 417 TYR A CA   1 
ATOM   6336 C C    . TYR A 1 425 ? 18.29050  -12.39025 18.57602  1.000 19.21217  ? 417 TYR A C    1 
ATOM   6337 O O    . TYR A 1 425 ? 17.26809  -12.44322 19.26722  1.000 16.79617  ? 417 TYR A O    1 
ATOM   6338 C CB   . TYR A 1 425 ? 18.66306  -10.61836 16.81752  1.000 15.18031  ? 417 TYR A CB   1 
ATOM   6339 C CG   . TYR A 1 425 ? 17.20233  -10.57314 16.44285  1.000 16.94594  ? 417 TYR A CG   1 
ATOM   6340 C CD1  . TYR A 1 425 ? 16.45350  -9.42157  16.64318  1.000 16.50577  ? 417 TYR A CD1  1 
ATOM   6341 C CD2  . TYR A 1 425 ? 16.57178  -11.67952 15.88843  1.000 15.11424  ? 417 TYR A CD2  1 
ATOM   6342 C CE1  . TYR A 1 425 ? 15.11742  -9.37496  16.30839  1.000 13.28316  ? 417 TYR A CE1  1 
ATOM   6343 C CE2  . TYR A 1 425 ? 15.21591  -11.64596 15.55457  1.000 18.94389  ? 417 TYR A CE2  1 
ATOM   6344 C CZ   . TYR A 1 425 ? 14.50276  -10.48723 15.76259  1.000 18.05516  ? 417 TYR A CZ   1 
ATOM   6345 O OH   . TYR A 1 425 ? 13.17116  -10.43447 15.43070  1.000 17.08001  ? 417 TYR A OH   1 
ATOM   6346 H H    . TYR A 1 425 ? 20.85409  -11.07065 17.74418  1.000 19.09498  ? 417 TYR A H    1 
ATOM   6347 H HA   . TYR A 1 425 ? 18.55658  -10.39212 18.85954  1.000 17.96399  ? 417 TYR A HA   1 
ATOM   6348 H HB2  . TYR A 1 425 ? 19.02524  -9.72825  16.68548  1.000 18.23340  ? 417 TYR A HB2  1 
ATOM   6349 H HB3  . TYR A 1 425 ? 19.09794  -11.24563 16.21893  1.000 18.23340  ? 417 TYR A HB3  1 
ATOM   6350 H HD1  . TYR A 1 425 ? 16.85996  -8.66943  17.00920  1.000 19.82395  ? 417 TYR A HD1  1 
ATOM   6351 H HD2  . TYR A 1 425 ? 17.06071  -12.45598 15.73690  1.000 18.15411  ? 417 TYR A HD2  1 
ATOM   6352 H HE1  . TYR A 1 425 ? 14.62937  -8.59597  16.44942  1.000 15.95681  ? 417 TYR A HE1  1 
ATOM   6353 H HE2  . TYR A 1 425 ? 14.80034  -12.39687 15.19634  1.000 22.74969  ? 417 TYR A HE2  1 
ATOM   6354 H HH   . TYR A 1 425 ? 12.90449  -11.19411 15.19107  1.000 20.51303  ? 417 TYR A HH   1 
ATOM   6355 N N    . ASP A 1 426 ? 18.86151  -13.48748 18.07506  1.000 23.82822  ? 418 ASP A N    1 
ATOM   6356 C CA   . ASP A 1 426 ? 18.20602  -14.78643 18.21099  1.000 23.44514  ? 418 ASP A CA   1 
ATOM   6357 C C    . ASP A 1 426 ? 18.14194  -15.23615 19.66399  1.000 24.03789  ? 418 ASP A C    1 
ATOM   6358 O O    . ASP A 1 426 ? 17.20126  -15.93439 20.05856  1.000 27.84466  ? 418 ASP A O    1 
ATOM   6359 C CB   . ASP A 1 426 ? 18.93800  -15.83784 17.37589  1.000 26.80613  ? 418 ASP A CB   1 
ATOM   6360 C CG   . ASP A 1 426 ? 18.64135  -15.72660 15.89352  1.000 35.47803  ? 418 ASP A CG   1 
ATOM   6361 O OD1  . ASP A 1 426 ? 17.76001  -14.92889 15.51494  1.000 25.82555  ? 418 ASP A OD1  1 
ATOM   6362 O OD2  . ASP A 1 426 ? 19.29795  -16.44014 15.10675  1.000 30.85038  ? 418 ASP A OD2  1 
ATOM   6363 H H    . ASP A 1 426 ? 19.61431  -13.50621 17.65967  1.000 28.61089  ? 418 ASP A H    1 
ATOM   6364 H HA   . ASP A 1 426 ? 17.29923  -14.70788 17.87564  1.000 28.15120  ? 418 ASP A HA   1 
ATOM   6365 H HB2  . ASP A 1 426 ? 19.89397  -15.72852 17.49867  1.000 32.18438  ? 418 ASP A HB2  1 
ATOM   6366 H HB3  . ASP A 1 426 ? 18.66452  -16.72071 17.67024  1.000 32.18438  ? 418 ASP A HB3  1 
ATOM   6367 N N    . ASN A 1 427 ? 19.12162  -14.84547 20.47375  1.000 22.43815  ? 419 ASN A N    1 
ATOM   6368 C CA   . ASN A 1 427 ? 19.21074  -15.29479 21.85566  1.000 24.80581  ? 419 ASN A CA   1 
ATOM   6369 C C    . ASN A 1 427 ? 18.86923  -14.18838 22.84253  1.000 35.23948  ? 419 ASN A C    1 
ATOM   6370 O O    . ASN A 1 427 ? 19.17538  -14.30927 24.03278  1.000 26.25790  ? 419 ASN A O    1 
ATOM   6371 C CB   . ASN A 1 427 ? 20.61011  -15.84052 22.14447  1.000 28.83268  ? 419 ASN A CB   1 
ATOM   6372 C CG   . ASN A 1 427 ? 20.92268  -17.09846 21.35361  1.000 27.24712  ? 419 ASN A CG   1 
ATOM   6373 O OD1  . ASN A 1 427 ? 20.47546  -18.19195 21.69875  1.000 43.23948  ? 419 ASN A OD1  1 
ATOM   6374 N ND2  . ASN A 1 427 ? 21.68697  -16.94515 20.27935  1.000 30.57827  ? 419 ASN A ND2  1 
ATOM   6375 H H    . ASN A 1 427 ? 19.75488  -14.31244 20.24036  1.000 26.94280  ? 419 ASN A H    1 
ATOM   6376 H HA   . ASN A 1 427 ? 18.57317  -16.01435 21.98466  1.000 29.78400  ? 419 ASN A HA   1 
ATOM   6377 H HB2  . ASN A 1 427 ? 21.26720  -15.16689 21.90918  1.000 34.61624  ? 419 ASN A HB2  1 
ATOM   6378 H HB3  . ASN A 1 427 ? 20.67770  -16.05457 23.08814  1.000 34.61624  ? 419 ASN A HB3  1 
ATOM   6379 H HD21 . ASN A 1 427 ? 21.89297  -17.62692 19.79733  1.000 36.71095  ? 419 ASN A HD21 1 
ATOM   6380 H HD22 . ASN A 1 427 ? 21.97619  -16.16403 20.06532  1.000 36.71095  ? 419 ASN A HD22 1 
ATOM   6381 N N    . TRP A 1 428 ? 18.22181  -13.12485 22.37522  1.000 24.78583  ? 420 TRP A N    1 
ATOM   6382 C CA   . TRP A 1 428 ? 17.95764  -11.97151 23.22148  1.000 22.33663  ? 420 TRP A CA   1 
ATOM   6383 C C    . TRP A 1 428 ? 17.02274  -12.34545 24.36559  1.000 18.27588  ? 420 TRP A C    1 
ATOM   6384 O O    . TRP A 1 428 ? 16.04560  -13.07450 24.17831  1.000 23.11709  ? 420 TRP A O    1 
ATOM   6385 C CB   . TRP A 1 428 ? 17.34663  -10.82629 22.38991  1.000 20.37822  ? 420 TRP A CB   1 
ATOM   6386 C CG   . TRP A 1 428 ? 17.41417  -9.51351  23.09709  1.000 16.28669  ? 420 TRP A CG   1 
ATOM   6387 C CD1  . TRP A 1 428 ? 18.40907  -8.58482  23.00318  1.000 20.35435  ? 420 TRP A CD1  1 
ATOM   6388 C CD2  . TRP A 1 428 ? 16.47314  -8.99618  24.04863  1.000 19.93645  ? 420 TRP A CD2  1 
ATOM   6389 N NE1  . TRP A 1 428 ? 18.14664  -7.52751  23.83221  1.000 19.41180  ? 420 TRP A NE1  1 
ATOM   6390 C CE2  . TRP A 1 428 ? 16.95703  -7.74729  24.47506  1.000 17.55999  ? 420 TRP A CE2  1 
ATOM   6391 C CE3  . TRP A 1 428 ? 15.25878  -9.45747  24.56203  1.000 23.17482  ? 420 TRP A CE3  1 
ATOM   6392 C CZ2  . TRP A 1 428 ? 16.27925  -6.96103  25.40131  1.000 18.37011  ? 420 TRP A CZ2  1 
ATOM   6393 C CZ3  . TRP A 1 428 ? 14.58774  -8.67219  25.47208  1.000 19.53571  ? 420 TRP A CZ3  1 
ATOM   6394 C CH2  . TRP A 1 428 ? 15.10421  -7.44883  25.89342  1.000 14.91642  ? 420 TRP A CH2  1 
ATOM   6395 H H    . TRP A 1 428 ? 17.92573  -13.04783 21.57147  1.000 29.76002  ? 420 TRP A H    1 
ATOM   6396 H HA   . TRP A 1 428 ? 18.79183  -11.65704 23.60376  1.000 26.82098  ? 420 TRP A HA   1 
ATOM   6397 H HB2  . TRP A 1 428 ? 17.83392  -10.74513 21.55513  1.000 24.47089  ? 420 TRP A HB2  1 
ATOM   6398 H HB3  . TRP A 1 428 ? 16.41424  -11.02580 22.21174  1.000 24.47089  ? 420 TRP A HB3  1 
ATOM   6399 H HD1  . TRP A 1 428 ? 19.15699  -8.65921  22.45548  1.000 24.44224  ? 420 TRP A HD1  1 
ATOM   6400 H HE1  . TRP A 1 428 ? 18.64814  -6.83621  23.93325  1.000 23.31118  ? 420 TRP A HE1  1 
ATOM   6401 H HE3  . TRP A 1 428 ? 14.91101  -10.27756 24.29479  1.000 27.82681  ? 420 TRP A HE3  1 
ATOM   6402 H HZ2  . TRP A 1 428 ? 16.61343  -6.13700  25.67371  1.000 22.06115  ? 420 TRP A HZ2  1 
ATOM   6403 H HZ3  . TRP A 1 428 ? 13.77308  -8.96429  25.81254  1.000 23.45988  ? 420 TRP A HZ3  1 
ATOM   6404 H HH2  . TRP A 1 428 ? 14.63640  -6.95256  26.52569  1.000 17.91673  ? 420 TRP A HH2  1 
ATOM   6405 N N    . ASP A 1 429 ? 17.30676  -11.79315 25.54338  1.000 21.34171  ? 421 ASP A N    1 
ATOM   6406 C CA   . ASP A 1 429 ? 16.45752  -11.93800 26.71317  1.000 23.18657  ? 421 ASP A CA   1 
ATOM   6407 C C    . ASP A 1 429 ? 16.60428  -10.68401 27.56074  1.000 22.58602  ? 421 ASP A C    1 
ATOM   6408 O O    . ASP A 1 429 ? 17.55414  -9.90770  27.39793  1.000 22.37999  ? 421 ASP A O    1 
ATOM   6409 C CB   . ASP A 1 429 ? 16.83324  -13.18356 27.51904  1.000 28.78894  ? 421 ASP A CB   1 
ATOM   6410 C CG   . ASP A 1 429 ? 15.73868  -13.62062 28.47075  1.000 36.69872  ? 421 ASP A CG   1 
ATOM   6411 O OD1  . ASP A 1 429 ? 14.63746  -13.03519 28.43911  1.000 31.08192  ? 421 ASP A OD1  1 
ATOM   6412 O OD2  . ASP A 1 429 ? 15.98089  -14.56305 29.25374  1.000 36.99472  ? 421 ASP A OD2  1 
ATOM   6413 H H    . ASP A 1 429 ? 18.00718  -11.31646 25.69098  1.000 25.62707  ? 421 ASP A H    1 
ATOM   6414 H HA   . ASP A 1 429 ? 15.52909  -12.02289 26.44538  1.000 27.84090  ? 421 ASP A HA   1 
ATOM   6415 H HB2  . ASP A 1 429 ? 17.00743  -13.91526 26.90653  1.000 34.56375  ? 421 ASP A HB2  1 
ATOM   6416 H HB3  . ASP A 1 429 ? 17.62719  -12.99316 28.04277  1.000 34.56375  ? 421 ASP A HB3  1 
ATOM   6417 N N    . TRP A 1 430 ? 15.64940  -10.49017 28.46727  1.000 20.74016  ? 422 TRP A N    1 
ATOM   6418 C CA   . TRP A 1 430 ? 15.70300  -9.35000  29.36321  1.000 23.05041  ? 422 TRP A CA   1 
ATOM   6419 C C    . TRP A 1 430 ? 17.04794  -9.32728  30.08924  1.000 36.48551  ? 422 TRP A C    1 
ATOM   6420 O O    . TRP A 1 430 ? 17.45408  -10.35421 30.65203  1.000 28.22979  ? 422 TRP A O    1 
ATOM   6421 C CB   . TRP A 1 430 ? 14.56999  -9.42478  30.38090  1.000 24.27002  ? 422 TRP A CB   1 
ATOM   6422 C CG   . TRP A 1 430 ? 13.18123  -9.27236  29.83099  1.000 16.67314  ? 422 TRP A CG   1 
ATOM   6423 C CD1  . TRP A 1 430 ? 12.22558  -10.23843 29.75416  1.000 17.88091  ? 422 TRP A CD1  1 
ATOM   6424 C CD2  . TRP A 1 430 ? 12.58228  -8.07426  29.31768  1.000 11.45083  ? 422 TRP A CD2  1 
ATOM   6425 N NE1  . TRP A 1 430 ? 11.05858  -9.71532  29.23659  1.000 19.71128  ? 422 TRP A NE1  1 
ATOM   6426 C CE2  . TRP A 1 430 ? 11.25492  -8.38951  28.95681  1.000 15.78571  ? 422 TRP A CE2  1 
ATOM   6427 C CE3  . TRP A 1 430 ? 13.03458  -6.76585  29.13539  1.000 13.46108  ? 422 TRP A CE3  1 
ATOM   6428 C CZ2  . TRP A 1 430 ? 10.37994  -7.44485  28.40526  1.000 14.18778  ? 422 TRP A CZ2  1 
ATOM   6429 C CZ3  . TRP A 1 430 ? 12.16266  -5.83339  28.57443  1.000 15.15889  ? 422 TRP A CZ3  1 
ATOM   6430 C CH2  . TRP A 1 430 ? 10.85306  -6.18070  28.22428  1.000 15.06597  ? 422 TRP A CH2  1 
ATOM   6431 H H    . TRP A 1 430 ? 14.96751  -11.00201 28.57974  1.000 24.90522  ? 422 TRP A H    1 
ATOM   6432 H HA   . TRP A 1 430 ? 15.60494  -8.53069  28.85328  1.000 27.67752  ? 422 TRP A HA   1 
ATOM   6433 H HB2  . TRP A 1 430 ? 14.61164  -10.28961 30.81820  1.000 29.14105  ? 422 TRP A HB2  1 
ATOM   6434 H HB3  . TRP A 1 430 ? 14.69965  -8.71733  31.03174  1.000 29.14105  ? 422 TRP A HB3  1 
ATOM   6435 H HD1  . TRP A 1 430 ? 12.34245  -11.12391 30.01331  1.000 21.47411  ? 422 TRP A HD1  1 
ATOM   6436 H HE1  . TRP A 1 430 ? 10.32770  -10.15061 29.11040  1.000 23.67056  ? 422 TRP A HE1  1 
ATOM   6437 H HE3  . TRP A 1 430 ? 13.89737  -6.52196  29.38239  1.000 16.17032  ? 422 TRP A HE3  1 
ATOM   6438 H HZ2  . TRP A 1 430 ? 9.50900   -7.67231  28.17155  1.000 17.04236  ? 422 TRP A HZ2  1 
ATOM   6439 H HZ3  . TRP A 1 430 ? 12.45738  -4.96321  28.43011  1.000 18.20769  ? 422 TRP A HZ3  1 
ATOM   6440 H HH2  . TRP A 1 430 ? 10.29322  -5.53369  27.85979  1.000 18.09618  ? 422 TRP A HH2  1 
ATOM   6441 N N    . PRO A 1 431 ? 17.76362  -8.20683  30.09702  1.000 26.34275  ? 423 PRO A N    1 
ATOM   6442 C CA   . PRO A 1 431 ? 19.05572  -8.15106  30.79177  1.000 38.56567  ? 423 PRO A CA   1 
ATOM   6443 C C    . PRO A 1 431 ? 18.86678  -8.01729  32.30119  1.000 49.28390  ? 423 PRO A C    1 
ATOM   6444 O O    . PRO A 1 431 ? 17.75566  -7.87566  32.80824  1.000 57.56733  ? 423 PRO A O    1 
ATOM   6445 C CB   . PRO A 1 431 ? 19.72608  -6.91038  30.19301  1.000 41.84954  ? 423 PRO A CB   1 
ATOM   6446 C CG   . PRO A 1 431 ? 18.59268  -6.02418  29.80321  1.000 45.90752  ? 423 PRO A CG   1 
ATOM   6447 C CD   . PRO A 1 431 ? 17.46092  -6.94956  29.38400  1.000 35.45910  ? 423 PRO A CD   1 
ATOM   6448 H HA   . PRO A 1 431 ? 19.58697  -8.93919  30.59805  1.000 46.29582  ? 423 PRO A HA   1 
ATOM   6449 H HB2  . PRO A 1 431 ? 20.28957  -6.48411  30.85760  1.000 50.23647  ? 423 PRO A HB2  1 
ATOM   6450 H HB3  . PRO A 1 431 ? 20.25579  -7.15981  29.41965  1.000 50.23647  ? 423 PRO A HB3  1 
ATOM   6451 H HG2  . PRO A 1 431 ? 18.32787  -5.48029  30.56146  1.000 55.10604  ? 423 PRO A HG2  1 
ATOM   6452 H HG3  . PRO A 1 431 ? 18.86193  -5.45553  29.06494  1.000 55.10604  ? 423 PRO A HG3  1 
ATOM   6453 H HD2  . PRO A 1 431 ? 16.60299  -6.59310  29.66291  1.000 42.56795  ? 423 PRO A HD2  1 
ATOM   6454 H HD3  . PRO A 1 431 ? 17.46644  -7.08786  28.42393  1.000 42.56795  ? 423 PRO A HD3  1 
ATOM   6455 N N    . GLN A 1 432 ? 19.98650  -8.06076  33.01657  1.000 78.20690  ? 424 GLN A N    1 
ATOM   6456 C CA   . GLN A 1 432 ? 19.99460  -7.89406  34.46509  1.000 81.59358  ? 424 GLN A CA   1 
ATOM   6457 C C    . GLN A 1 432 ? 20.98745  -6.80346  34.86971  1.000 80.08566  ? 424 GLN A C    1 
ATOM   6458 O O    . GLN A 1 432 ? 21.34930  -5.93738  34.06998  1.000 80.32634  ? 424 GLN A O    1 
ATOM   6459 C CB   . GLN A 1 432 ? 20.34922  -9.21058  35.15415  1.000 64.40553  ? 424 GLN A CB   1 
ATOM   6460 C CG   . GLN A 1 432 ? 19.19873  -10.20200 35.23488  1.000 81.82424  ? 424 GLN A CG   1 
ATOM   6461 C CD   . GLN A 1 432 ? 19.05958  -11.04233 33.97762  1.000 75.10821  ? 424 GLN A CD   1 
ATOM   6462 O OE1  . GLN A 1 432 ? 18.00337  -11.06233 33.34628  1.000 75.09173  ? 424 GLN A OE1  1 
ATOM   6463 N NE2  . GLN A 1 432 ? 20.12836  -11.74255 33.60872  1.000 66.31309  ? 424 GLN A NE2  1 
ATOM   6464 O OXT  . GLN A 1 432 ? 21.45410  -6.76026  36.00950  1.000 61.48061  ? 424 GLN A OXT  1 
ATOM   6465 H H    . GLN A 1 432 ? 20.76782  -8.18775  32.68040  1.000 93.86530  ? 424 GLN A H    1 
ATOM   6466 H HA   . GLN A 1 432 ? 19.11018  -7.63157  34.76475  1.000 97.92932  ? 424 GLN A HA   1 
ATOM   6467 H HB2  . GLN A 1 432 ? 21.06890  -9.63458  34.66102  1.000 77.30366  ? 424 GLN A HB2  1 
ATOM   6468 H HB3  . GLN A 1 432 ? 20.63628  -9.01858  36.06059  1.000 77.30366  ? 424 GLN A HB3  1 
ATOM   6469 H HG2  . GLN A 1 432 ? 19.35019  -10.80212 35.98175  1.000 98.20612  ? 424 GLN A HG2  1 
ATOM   6470 H HG3  . GLN A 1 432 ? 18.36986  -9.71484  35.36354  1.000 98.20612  ? 424 GLN A HG3  1 
ATOM   6471 H HE21 . GLN A 1 432 ? 20.84962  -11.70430 34.07554  1.000 79.59273  ? 424 GLN A HE21 1 
ATOM   6472 H HE22 . GLN A 1 432 ? 20.09823  -12.23361 32.90334  1.000 79.59273  ? 424 GLN A HE22 1 
HETATM 6473 P P    . PO4 B 2 .   ? -8.33058  6.58127   25.25746  1.000 41.64453  ? 501 PO4 A P    1 
HETATM 6474 O O1   . PO4 B 2 .   ? -7.08460  7.02477   24.51351  1.000 30.87465  ? 501 PO4 A O1   1 
HETATM 6475 O O2   . PO4 B 2 .   ? -9.47833  7.48307   24.86637  1.000 37.83269  ? 501 PO4 A O2   1 
HETATM 6476 O O3   . PO4 B 2 .   ? -8.65324  5.14789   24.89498  1.000 54.77870  ? 501 PO4 A O3   1 
HETATM 6477 O O4   . PO4 B 2 .   ? -8.11193  6.67903   26.74756  1.000 35.27171  ? 501 PO4 A O4   1 
HETATM 6478 P P    . PO4 C 2 .   ? -8.84292  -12.33127 20.41229  1.000 102.78802 ? 502 PO4 A P    1 
HETATM 6479 O O1   . PO4 C 2 .   ? -7.44542  -11.91983 20.80485  1.000 65.75355  ? 502 PO4 A O1   1 
HETATM 6480 O O2   . PO4 C 2 .   ? -9.54676  -11.17489 19.74337  1.000 58.16305  ? 502 PO4 A O2   1 
HETATM 6481 O O3   . PO4 C 2 .   ? -8.76740  -13.49012 19.44598  1.000 86.14401  ? 502 PO4 A O3   1 
HETATM 6482 O O4   . PO4 C 2 .   ? -9.60631  -12.74002 21.64977  1.000 73.41364  ? 502 PO4 A O4   1 
HETATM 6483 O O    . HOH D 3 .   ? 13.16474  8.55641   34.85667  1.000 47.28286  ? 601 HOH A O    1 
HETATM 6484 O O    . HOH D 3 .   ? -12.02041 -14.47670 23.63869  1.000 49.11644  ? 602 HOH A O    1 
HETATM 6485 O O    . HOH D 3 .   ? 29.588    -17.512   3.804     1.000 54.80325  ? 603 HOH A O    1 
HETATM 6486 O O    . HOH D 3 .   ? 25.18354  -12.00849 -5.13149  1.000 50.79169  ? 604 HOH A O    1 
HETATM 6487 O O    . HOH D 3 .   ? 8.31346   -13.66892 21.66562  1.000 41.26675  ? 605 HOH A O    1 
HETATM 6488 O O    . HOH D 3 .   ? -6.51790  -11.83899 30.92103  1.000 24.92332  ? 606 HOH A O    1 
HETATM 6489 O O    . HOH D 3 .   ? 29.37189  -2.16040  -20.98879 1.000 44.20318  ? 607 HOH A O    1 
HETATM 6490 O O    . HOH D 3 .   ? -4.52395  -12.04707 34.14037  1.000 20.32107  ? 608 HOH A O    1 
HETATM 6491 O O    . HOH D 3 .   ? 24.90946  8.31998   3.46876   1.000 37.71651  ? 609 HOH A O    1 
HETATM 6492 O O    . HOH D 3 .   ? 28.22683  0.18394   -30.79335 1.000 46.67331  ? 610 HOH A O    1 
HETATM 6493 O O    . HOH D 3 .   ? 28.81405  15.11385  -10.46835 1.000 42.74182  ? 611 HOH A O    1 
HETATM 6494 O O    . HOH D 3 .   ? 15.68110  3.33752   -27.16809 1.000 56.23555  ? 612 HOH A O    1 
HETATM 6495 O O    . HOH D 3 .   ? 29.11364  -7.79324  9.00777   1.000 37.80947  ? 613 HOH A O    1 
HETATM 6496 O O    . HOH D 3 .   ? -12.75198 8.57819   34.43894  1.000 32.56864  ? 614 HOH A O    1 
HETATM 6497 O O    . HOH D 3 .   ? 14.87486  13.01903  7.44488   1.000 31.62408  ? 615 HOH A O    1 
HETATM 6498 O O    . HOH D 3 .   ? -0.54701  -10.22947 0.16754   1.000 29.50489  ? 616 HOH A O    1 
HETATM 6499 O O    . HOH D 3 .   ? 30.17370  1.62243   -22.65282 1.000 41.19848  ? 617 HOH A O    1 
HETATM 6500 O O    . HOH D 3 .   ? 29.34136  -12.18089 10.19115  1.000 35.69377  ? 618 HOH A O    1 
HETATM 6501 O O    . HOH D 3 .   ? 20.14566  -20.89372 0.96578   1.000 47.51078  ? 619 HOH A O    1 
HETATM 6502 O O    . HOH D 3 .   ? 21.07258  -11.75661 -19.82464 1.000 40.80164  ? 620 HOH A O    1 
HETATM 6503 O O    . HOH D 3 .   ? 7.49570   10.58979  -2.35728  1.000 21.28290  ? 621 HOH A O    1 
HETATM 6504 O O    . HOH D 3 .   ? 21.31787  -5.86103  -5.38378  1.000 26.10824  ? 622 HOH A O    1 
HETATM 6505 O O    . HOH D 3 .   ? 6.95862   -11.17182 33.27725  1.000 16.83777  ? 623 HOH A O    1 
HETATM 6506 O O    . HOH D 3 .   ? 9.87616   -8.19981  -6.15335  1.000 26.65771  ? 624 HOH A O    1 
HETATM 6507 O O    . HOH D 3 .   ? 33.73797  -10.89428 -3.92621  1.000 43.96602  ? 625 HOH A O    1 
HETATM 6508 O O    . HOH D 3 .   ? -7.13518  7.40402   22.02359  1.000 25.14998  ? 626 HOH A O    1 
HETATM 6509 O O    . HOH D 3 .   ? 3.87207   14.96493  9.66944   1.000 34.50865  ? 627 HOH A O    1 
HETATM 6510 O O    . HOH D 3 .   ? 8.67782   -16.22385 -8.08184  1.000 22.82540  ? 628 HOH A O    1 
HETATM 6511 O O    . HOH D 3 .   ? 9.84296   -12.33398 30.97296  1.000 31.93225  ? 629 HOH A O    1 
HETATM 6512 O O    . HOH D 3 .   ? 12.05209  -19.07984 -19.37458 1.000 29.85231  ? 630 HOH A O    1 
HETATM 6513 O O    . HOH D 3 .   ? 24.33900  -1.87694  10.92665  1.000 28.76360  ? 631 HOH A O    1 
HETATM 6514 O O    . HOH D 3 .   ? 19.01960  11.97357  17.66013  1.000 34.24573  ? 632 HOH A O    1 
HETATM 6515 O O    . HOH D 3 .   ? 11.29090  19.30401  18.07248  1.000 27.55920  ? 633 HOH A O    1 
HETATM 6516 O O    . HOH D 3 .   ? 35.00603  -4.21427  5.84095   1.000 36.60700  ? 634 HOH A O    1 
HETATM 6517 O O    . HOH D 3 .   ? 2.09184   -4.35800  11.39455  1.000 18.47292  ? 635 HOH A O    1 
HETATM 6518 O O    . HOH D 3 .   ? -0.196    -19.728   29.528    1.000 35.98495  ? 636 HOH A O    1 
HETATM 6519 O O    . HOH D 3 .   ? 22.15171  9.75522   4.01859   1.000 26.73497  ? 637 HOH A O    1 
HETATM 6520 O O    . HOH D 3 .   ? 6.91031   -9.82283  26.61632  1.000 13.54558  ? 638 HOH A O    1 
HETATM 6521 O O    . HOH D 3 .   ? 12.90056  8.76437   8.81255   1.000 17.04573  ? 639 HOH A O    1 
HETATM 6522 O O    . HOH D 3 .   ? -1.17945  23.16621  21.42544  1.000 35.29209  ? 640 HOH A O    1 
HETATM 6523 O O    . HOH D 3 .   ? 4.35624   8.96198   38.70382  1.000 43.36643  ? 641 HOH A O    1 
HETATM 6524 O O    . HOH D 3 .   ? 24.54791  -7.66477  -14.99298 1.000 37.13681  ? 642 HOH A O    1 
HETATM 6525 O O    . HOH D 3 .   ? -4.10983  -1.13164  8.15392   1.000 31.25929  ? 643 HOH A O    1 
HETATM 6526 O O    . HOH D 3 .   ? 6.19845   20.34829  14.33619  1.000 30.54016  ? 644 HOH A O    1 
HETATM 6527 O O    . HOH D 3 .   ? -2.07611  -5.17239  29.95962  1.000 21.35747  ? 645 HOH A O    1 
HETATM 6528 O O    . HOH D 3 .   ? 7.819     -19.935   -19.890   1.000 16.83799  ? 646 HOH A O    1 
HETATM 6529 O O    . HOH D 3 .   ? 30.59978  7.35386   2.85514   1.000 38.83384  ? 647 HOH A O    1 
HETATM 6530 O O    . HOH D 3 .   ? 15.68186  1.37937   -25.40991 1.000 22.56786  ? 648 HOH A O    1 
HETATM 6531 O O    . HOH D 3 .   ? -4.19815  0.99967   20.15318  1.000 12.62513  ? 649 HOH A O    1 
HETATM 6532 O O    . HOH D 3 .   ? -7.47933  20.76835  21.87490  1.000 37.64308  ? 650 HOH A O    1 
HETATM 6533 O O    . HOH D 3 .   ? 19.55275  -9.09456  -7.07416  1.000 33.30920  ? 651 HOH A O    1 
HETATM 6534 O O    . HOH D 3 .   ? 4.55197   -2.12146  13.13471  1.000 14.81745  ? 652 HOH A O    1 
HETATM 6535 O O    . HOH D 3 .   ? -6.32541  -13.39443 23.38231  1.000 35.73379  ? 653 HOH A O    1 
HETATM 6536 O O    . HOH D 3 .   ? 1.17078   -12.71617 21.63997  1.000 26.68990  ? 654 HOH A O    1 
HETATM 6537 O O    . HOH D 3 .   ? 2.22394   16.35089  11.69761  1.000 28.56331  ? 655 HOH A O    1 
HETATM 6538 O O    . HOH D 3 .   ? 14.56924  -19.77676 -17.28697 1.000 35.50311  ? 656 HOH A O    1 
HETATM 6539 O O    . HOH D 3 .   ? -7.82306  -1.98576  18.81454  1.000 25.95766  ? 657 HOH A O    1 
HETATM 6540 O O    . HOH D 3 .   ? -3.17051  25.33975  22.92271  1.000 41.48960  ? 658 HOH A O    1 
HETATM 6541 O O    . HOH D 3 .   ? -3.03554  6.66754   41.18116  1.000 36.10172  ? 659 HOH A O    1 
HETATM 6542 O O    . HOH D 3 .   ? 9.031     -12.505   34.756    1.000 35.23839  ? 660 HOH A O    1 
HETATM 6543 O O    . HOH D 3 .   ? 19.19884  5.35150   20.42958  1.000 27.30510  ? 661 HOH A O    1 
HETATM 6544 O O    . HOH D 3 .   ? 13.57922  -15.09933 -7.41124  1.000 21.42950  ? 662 HOH A O    1 
HETATM 6545 O O    . HOH D 3 .   ? -10.99702 0.91085   16.94259  1.000 44.50248  ? 663 HOH A O    1 
HETATM 6546 O O    . HOH D 3 .   ? 6.11377   8.18642   3.93938   1.000 29.35340  ? 664 HOH A O    1 
HETATM 6547 O O    . HOH D 3 .   ? 15.29618  -1.14978  -26.96107 1.000 25.27586  ? 665 HOH A O    1 
HETATM 6548 O O    . HOH D 3 .   ? -2.13177  -2.38260  32.21627  1.000 16.65865  ? 666 HOH A O    1 
HETATM 6549 O O    . HOH D 3 .   ? 14.36427  -5.10568  -20.87198 1.000 13.75911  ? 667 HOH A O    1 
HETATM 6550 O O    . HOH D 3 .   ? 9.21093   -5.50856  -7.90073  1.000 16.94353  ? 668 HOH A O    1 
HETATM 6551 O O    . HOH D 3 .   ? 7.50064   -12.68865 9.54817   1.000 29.33182  ? 669 HOH A O    1 
HETATM 6552 O O    . HOH D 3 .   ? 0.48014   -11.19659 -3.20471  1.000 37.40192  ? 670 HOH A O    1 
HETATM 6553 O O    . HOH D 3 .   ? 21.00038  9.69982   -17.33859 1.000 48.83786  ? 671 HOH A O    1 
HETATM 6554 O O    . HOH D 3 .   ? -7.76890  11.52112  37.28870  1.000 22.15655  ? 672 HOH A O    1 
HETATM 6555 O O    . HOH D 3 .   ? 5.02289   -13.82762 21.36858  1.000 39.95701  ? 673 HOH A O    1 
HETATM 6556 O O    . HOH D 3 .   ? 1.423     -16.687   34.127    1.000 19.62385  ? 674 HOH A O    1 
HETATM 6557 O O    . HOH D 3 .   ? 11.62334  6.16329   31.16951  1.000 18.54721  ? 675 HOH A O    1 
HETATM 6558 O O    . HOH D 3 .   ? 8.01455   -9.79511  11.63501  1.000 20.88309  ? 676 HOH A O    1 
HETATM 6559 O O    . HOH D 3 .   ? -1.98595  -0.00974  -15.83525 1.000 36.19111  ? 677 HOH A O    1 
HETATM 6560 O O    . HOH D 3 .   ? 21.36140  -1.19387  19.27717  1.000 30.79786  ? 678 HOH A O    1 
HETATM 6561 O O    . HOH D 3 .   ? 4.70420   6.83926   9.90486   1.000 18.63883  ? 679 HOH A O    1 
HETATM 6562 O O    . HOH D 3 .   ? 16.32923  9.31011   -9.62138  1.000 30.13075  ? 680 HOH A O    1 
HETATM 6563 O O    . HOH D 3 .   ? 21.53257  1.20903   16.31368  1.000 28.55440  ? 681 HOH A O    1 
HETATM 6564 O O    . HOH D 3 .   ? 9.16134   10.82671  9.64736   1.000 21.77200  ? 682 HOH A O    1 
HETATM 6565 O O    . HOH D 3 .   ? -5.50155  12.73890  37.79537  1.000 27.88395  ? 683 HOH A O    1 
HETATM 6566 O O    . HOH D 3 .   ? 0.59217   -11.19266 3.87006   1.000 29.20448  ? 684 HOH A O    1 
HETATM 6567 O O    . HOH D 3 .   ? 8.79490   8.57515   7.85374   1.000 30.09288  ? 685 HOH A O    1 
HETATM 6568 O O    . HOH D 3 .   ? 0.14809   2.94751   3.81669   1.000 32.64128  ? 686 HOH A O    1 
HETATM 6569 O O    . HOH D 3 .   ? -6.522    -19.633   29.972    1.000 20.07064  ? 687 HOH A O    1 
HETATM 6570 O O    . HOH D 3 .   ? 3.99144   -14.11432 -0.30411  1.000 28.51804  ? 688 HOH A O    1 
HETATM 6571 O O    . HOH D 3 .   ? 8.11403   -7.05099  -20.62822 1.000 31.70144  ? 689 HOH A O    1 
HETATM 6572 O O    . HOH D 3 .   ? -2.90814  -6.06351  20.64411  1.000 11.52599  ? 690 HOH A O    1 
HETATM 6573 O O    . HOH D 3 .   ? 25.12934  3.60237   22.15664  1.000 50.14114  ? 691 HOH A O    1 
HETATM 6574 O O    . HOH D 3 .   ? 21.65850  -17.50513 15.93792  1.000 45.55518  ? 692 HOH A O    1 
HETATM 6575 O O    . HOH D 3 .   ? -3.49122  -3.47146  11.88043  1.000 30.38075  ? 693 HOH A O    1 
HETATM 6576 O O    . HOH D 3 .   ? -4.92379  -3.44962  -14.99399 1.000 37.43658  ? 694 HOH A O    1 
HETATM 6577 O O    . HOH D 3 .   ? 5.78861   1.24692   -22.87591 1.000 25.97534  ? 695 HOH A O    1 
HETATM 6578 O O    . HOH D 3 .   ? 21.12160  0.17821   -29.15561 1.000 36.96998  ? 696 HOH A O    1 
HETATM 6579 O O    . HOH D 3 .   ? -0.72246  -12.69514 23.47462  1.000 19.88040  ? 697 HOH A O    1 
HETATM 6580 O O    . HOH D 3 .   ? 15.14377  10.59959  26.44356  1.000 20.59456  ? 698 HOH A O    1 
HETATM 6581 O O    . HOH D 3 .   ? -0.30534  17.43674  29.57373  1.000 15.38375  ? 699 HOH A O    1 
HETATM 6582 O O    . HOH D 3 .   ? 2.47720   -4.86883  -6.26200  1.000 28.48749  ? 700 HOH A O    1 
HETATM 6583 O O    . HOH D 3 .   ? 16.79224  -1.46629  -29.28759 1.000 30.07730  ? 701 HOH A O    1 
HETATM 6584 O O    . HOH D 3 .   ? 23.77641  10.11440  -12.11911 1.000 25.33660  ? 702 HOH A O    1 
HETATM 6585 O O    . HOH D 3 .   ? 29.18861  -15.93636 -3.22826  1.000 41.77686  ? 703 HOH A O    1 
HETATM 6586 O O    . HOH D 3 .   ? -6.28606  18.83380  34.04883  1.000 23.15164  ? 704 HOH A O    1 
HETATM 6587 O O    . HOH D 3 .   ? -1.83433  5.18902   -12.00651 1.000 33.94452  ? 705 HOH A O    1 
HETATM 6588 O O    . HOH D 3 .   ? 22.78255  -0.67800  -1.48494  1.000 16.14725  ? 706 HOH A O    1 
HETATM 6589 O O    . HOH D 3 .   ? 18.85336  8.01688   -9.96418  1.000 21.77878  ? 707 HOH A O    1 
HETATM 6590 O O    . HOH D 3 .   ? -8.97593  -7.07708  23.28937  1.000 19.23747  ? 708 HOH A O    1 
HETATM 6591 O O    . HOH D 3 .   ? 9.60175   -3.32596  -26.08141 1.000 26.45856  ? 709 HOH A O    1 
HETATM 6592 O O    . HOH D 3 .   ? 20.04658  5.84754   -5.88182  1.000 17.23285  ? 710 HOH A O    1 
HETATM 6593 O O    . HOH D 3 .   ? -2.70348  -2.12435  13.85605  1.000 19.44466  ? 711 HOH A O    1 
HETATM 6594 O O    . HOH D 3 .   ? -0.88642  12.33397  16.54848  1.000 12.76232  ? 712 HOH A O    1 
HETATM 6595 O O    . HOH D 3 .   ? 18.10844  -14.82313 -8.57020  1.000 45.63415  ? 713 HOH A O    1 
HETATM 6596 O O    . HOH D 3 .   ? 1.68433   -11.88430 -5.39087  1.000 35.03752  ? 714 HOH A O    1 
HETATM 6597 O O    . HOH D 3 .   ? 9.01702   23.32228  25.09008  1.000 48.53768  ? 715 HOH A O    1 
HETATM 6598 O O    . HOH D 3 .   ? 17.76635  6.17289   -16.40019 1.000 21.67861  ? 716 HOH A O    1 
HETATM 6599 O O    . HOH D 3 .   ? 15.15559  -7.22970  -24.32009 1.000 28.64659  ? 717 HOH A O    1 
HETATM 6600 O O    . HOH D 3 .   ? -0.23898  3.50467   6.56513   1.000 17.68279  ? 718 HOH A O    1 
HETATM 6601 O O    . HOH D 3 .   ? 24.52979  16.66121  -10.74538 1.000 36.32909  ? 719 HOH A O    1 
HETATM 6602 O O    . HOH D 3 .   ? 8.53289   -13.45281 -15.21371 1.000 14.86471  ? 720 HOH A O    1 
HETATM 6603 O O    . HOH D 3 .   ? 28.80883  -3.76139  -16.91894 1.000 31.27107  ? 721 HOH A O    1 
HETATM 6604 O O    . HOH D 3 .   ? 13.36400  7.79706   32.59318  1.000 33.16937  ? 722 HOH A O    1 
HETATM 6605 O O    . HOH D 3 .   ? 6.53308   20.66502  17.13398  1.000 17.30193  ? 723 HOH A O    1 
HETATM 6606 O O    . HOH D 3 .   ? 21.28002  -3.72169  26.84440  1.000 37.78703  ? 724 HOH A O    1 
HETATM 6607 O O    . HOH D 3 .   ? 18.37690  -2.70073  30.98261  1.000 32.51944  ? 725 HOH A O    1 
HETATM 6608 O O    . HOH D 3 .   ? 18.68625  -16.45292 12.38898  1.000 32.25333  ? 726 HOH A O    1 
HETATM 6609 O O    . HOH D 3 .   ? 17.49561  -16.32971 -21.22588 1.000 34.26561  ? 727 HOH A O    1 
HETATM 6610 O O    . HOH D 3 .   ? 23.34918  -4.59876  17.96301  1.000 27.31038  ? 728 HOH A O    1 
HETATM 6611 O O    . HOH D 3 .   ? 7.41819   -11.60716 5.43178   1.000 13.23197  ? 729 HOH A O    1 
HETATM 6612 O O    . HOH D 3 .   ? 4.16757   -0.73950  -21.79067 1.000 28.17223  ? 730 HOH A O    1 
HETATM 6613 O O    . HOH D 3 .   ? 20.29449  5.71509   -14.96035 1.000 22.54603  ? 731 HOH A O    1 
HETATM 6614 O O    . HOH D 3 .   ? 16.03861  7.31209   32.85781  1.000 34.39999  ? 732 HOH A O    1 
HETATM 6615 O O    . HOH D 3 .   ? 13.01934  14.69371  26.06282  1.000 32.48005  ? 733 HOH A O    1 
HETATM 6616 O O    . HOH D 3 .   ? 0.53715   -2.84812  -3.73723  1.000 29.54714  ? 734 HOH A O    1 
HETATM 6617 O O    . HOH D 3 .   ? 7.07997   -19.12916 -10.27436 1.000 39.85907  ? 735 HOH A O    1 
HETATM 6618 O O    . HOH D 3 .   ? 19.97156  -8.48837  27.38067  1.000 39.73828  ? 736 HOH A O    1 
HETATM 6619 O O    . HOH D 3 .   ? 21.75876  -18.93599 18.30672  1.000 46.82535  ? 737 HOH A O    1 
HETATM 6620 O O    . HOH D 3 .   ? -1.32358  -6.24947  37.14249  1.000 29.79998  ? 738 HOH A O    1 
HETATM 6621 O O    . HOH D 3 .   ? 9.94648   4.21403   32.44697  1.000 16.37799  ? 739 HOH A O    1 
HETATM 6622 O O    . HOH D 3 .   ? 26.46519  -5.57159  -26.91752 1.000 44.30149  ? 740 HOH A O    1 
HETATM 6623 O O    . HOH D 3 .   ? 7.37024   10.71212  5.50257   1.000 42.56904  ? 741 HOH A O    1 
HETATM 6624 O O    . HOH D 3 .   ? -11.52876 16.97106  21.90468  1.000 33.14433  ? 742 HOH A O    1 
HETATM 6625 O O    . HOH D 3 .   ? 16.39524  16.25417  20.73393  1.000 38.35716  ? 743 HOH A O    1 
HETATM 6626 O O    . HOH D 3 .   ? 1.53865   13.21595  6.98735   1.000 37.54403  ? 744 HOH A O    1 
HETATM 6627 O O    . HOH D 3 .   ? -1.68116  -8.69126  38.20703  1.000 20.37054  ? 745 HOH A O    1 
HETATM 6628 O O    . HOH D 3 .   ? 7.635     -6.932    35.980    1.000 15.96234  ? 746 HOH A O    1 
HETATM 6629 O O    . HOH D 3 .   ? 23.00939  -4.45349  -6.95632  1.000 15.32681  ? 747 HOH A O    1 
HETATM 6630 O O    . HOH D 3 .   ? 3.72046   11.59950  -9.98907  1.000 34.45662  ? 748 HOH A O    1 
HETATM 6631 O O    . HOH D 3 .   ? -9.54748  -3.51835  30.07278  1.000 39.39233  ? 749 HOH A O    1 
HETATM 6632 O O    . HOH D 3 .   ? -0.21908  13.93312  7.72765   1.000 43.31710  ? 750 HOH A O    1 
HETATM 6633 O O    . HOH D 3 .   ? 7.98262   -15.71090 5.03314   1.000 26.51994  ? 751 HOH A O    1 
HETATM 6634 O O    . HOH D 3 .   ? -11.18185 1.13964   30.64859  1.000 46.45221  ? 752 HOH A O    1 
HETATM 6635 O O    . HOH D 3 .   ? 2.87110   -9.95250  -11.66762 1.000 32.33557  ? 753 HOH A O    1 
HETATM 6636 O O    . HOH D 3 .   ? 22.55195  -1.08011  13.44125  1.000 31.33971  ? 754 HOH A O    1 
HETATM 6637 O O    . HOH D 3 .   ? 21.39770  -11.33722 23.26003  1.000 30.82418  ? 755 HOH A O    1 
HETATM 6638 O O    . HOH D 3 .   ? -4.63789  5.77454   23.80114  1.000 18.57527  ? 756 HOH A O    1 
HETATM 6639 O O    . HOH D 3 .   ? -5.98969  3.93677   22.39724  1.000 25.20430  ? 757 HOH A O    1 
HETATM 6640 O O    . HOH D 3 .   ? -7.11746  18.23052  24.15713  1.000 19.02742  ? 758 HOH A O    1 
HETATM 6641 O O    . HOH D 3 .   ? 6.98521   6.99354   -17.79770 1.000 33.33751  ? 759 HOH A O    1 
HETATM 6642 O O    . HOH D 3 .   ? -1.05666  -11.34126 15.07919  1.000 14.71976  ? 760 HOH A O    1 
HETATM 6643 O O    . HOH D 3 .   ? 1.54765   7.92558   -7.06464  1.000 36.56576  ? 761 HOH A O    1 
HETATM 6644 O O    . HOH D 3 .   ? 6.91043   0.34846   -28.02432 1.000 19.85517  ? 762 HOH A O    1 
HETATM 6645 O O    . HOH D 3 .   ? -7.81141  -3.20429  13.46931  1.000 37.05945  ? 763 HOH A O    1 
HETATM 6646 O O    . HOH D 3 .   ? -5.37348  -8.20103  9.76146   1.000 27.25043  ? 764 HOH A O    1 
HETATM 6647 O O    . HOH D 3 .   ? 15.33116  11.39564  3.76159   1.000 20.64644  ? 765 HOH A O    1 
HETATM 6648 O O    . HOH D 3 .   ? 16.82978  9.64934   15.48816  1.000 21.46933  ? 766 HOH A O    1 
HETATM 6649 O O    . HOH D 3 .   ? 19.92503  -0.83350  12.93766  1.000 15.66867  ? 767 HOH A O    1 
HETATM 6650 O O    . HOH D 3 .   ? 17.26834  -14.41009 12.74660  1.000 29.79282  ? 768 HOH A O    1 
HETATM 6651 O O    . HOH D 3 .   ? 8.78814   -0.30047  35.29513  1.000 13.34911  ? 769 HOH A O    1 
HETATM 6652 O O    . HOH D 3 .   ? 15.46001  16.90715  24.44385  1.000 38.59058  ? 770 HOH A O    1 
HETATM 6653 O O    . HOH D 3 .   ? 1.33300   -1.53720  0.61421   1.000 21.91360  ? 771 HOH A O    1 
HETATM 6654 O O    . HOH D 3 .   ? 32.70447  -12.58213 -0.27733  1.000 36.00694  ? 772 HOH A O    1 
HETATM 6655 O O    . HOH D 3 .   ? -13.76998 10.04580  29.96057  1.000 30.78769  ? 773 HOH A O    1 
HETATM 6656 O O    . HOH D 3 .   ? 16.14084  -15.79913 -6.81795  1.000 35.19098  ? 774 HOH A O    1 
HETATM 6657 O O    . HOH D 3 .   ? 10.74485  12.78608  -3.86116  1.000 27.33839  ? 775 HOH A O    1 
HETATM 6658 O O    . HOH D 3 .   ? 13.29637  14.31201  12.09009  1.000 35.29120  ? 776 HOH A O    1 
HETATM 6659 O O    . HOH D 3 .   ? -6.92513  19.18958  17.28863  1.000 25.12941  ? 777 HOH A O    1 
HETATM 6660 O O    . HOH D 3 .   ? 12.40956  17.06021  27.67583  1.000 36.79907  ? 778 HOH A O    1 
HETATM 6661 O O    . HOH D 3 .   ? 21.50051  3.57884   -13.75163 1.000 19.81943  ? 779 HOH A O    1 
HETATM 6662 O O    . HOH D 3 .   ? 8.37873   -7.40712  13.19627  1.000 15.33559  ? 780 HOH A O    1 
HETATM 6663 O O    . HOH D 3 .   ? 8.50293   -10.95922 -13.59727 1.000 17.00616  ? 781 HOH A O    1 
HETATM 6664 O O    . HOH D 3 .   ? -0.15559  4.85997   -6.16815  1.000 39.80842  ? 782 HOH A O    1 
HETATM 6665 O O    . HOH D 3 .   ? -11.020   -19.100   32.282    1.000 35.47108  ? 783 HOH A O    1 
HETATM 6666 O O    . HOH D 3 .   ? 27.11946  -1.84306  -11.59220 1.000 28.29412  ? 784 HOH A O    1 
HETATM 6667 O O    . HOH D 3 .   ? 13.83935  -12.86563 -5.67251  1.000 21.51058  ? 785 HOH A O    1 
HETATM 6668 O O    . HOH D 3 .   ? 5.11267   -3.90599  -21.44199 1.000 37.19812  ? 786 HOH A O    1 
HETATM 6669 O O    . HOH D 3 .   ? 9.64466   16.77566  11.31675  1.000 29.35040  ? 787 HOH A O    1 
HETATM 6670 O O    . HOH D 3 .   ? 20.72395  3.18919   33.82213  1.000 41.33580  ? 788 HOH A O    1 
HETATM 6671 O O    . HOH D 3 .   ? 1.99293   5.86150   -1.39201  1.000 34.03181  ? 789 HOH A O    1 
HETATM 6672 O O    . HOH D 3 .   ? 5.30906   -13.17203 2.97148   1.000 12.92237  ? 790 HOH A O    1 
HETATM 6673 O O    . HOH D 3 .   ? 19.64029  -13.28204 -21.19003 1.000 37.90672  ? 791 HOH A O    1 
HETATM 6674 O O    . HOH D 3 .   ? 29.93615  8.26523   -1.16126  1.000 34.50470  ? 792 HOH A O    1 
HETATM 6675 O O    . HOH D 3 .   ? 3.31210   3.68714   41.94137  1.000 34.71051  ? 793 HOH A O    1 
HETATM 6676 O O    . HOH D 3 .   ? -3.21236  1.05244   38.89337  1.000 38.58889  ? 794 HOH A O    1 
HETATM 6677 O O    . HOH D 3 .   ? 11.80764  16.48831  13.42012  1.000 22.01103  ? 795 HOH A O    1 
HETATM 6678 O O    . HOH D 3 .   ? 22.95504  -0.05030  25.37727  1.000 43.00038  ? 796 HOH A O    1 
HETATM 6679 O O    . HOH D 3 .   ? 15.80760  7.19460   -20.51624 1.000 36.71376  ? 797 HOH A O    1 
HETATM 6680 O O    . HOH D 3 .   ? 6.94404   2.92251   35.45197  1.000 16.45748  ? 798 HOH A O    1 
HETATM 6681 O O    . HOH D 3 .   ? 9.56761   8.11273   31.31590  1.000 20.62013  ? 799 HOH A O    1 
HETATM 6682 O O    . HOH D 3 .   ? 6.67345   -10.40344 17.30419  1.000 13.88476  ? 800 HOH A O    1 
HETATM 6683 O O    . HOH D 3 .   ? 17.98341  16.01394  23.41911  1.000 47.73950  ? 801 HOH A O    1 
HETATM 6684 O O    . HOH D 3 .   ? 31.82978  5.00249   -20.18082 1.000 39.89093  ? 802 HOH A O    1 
HETATM 6685 O O    . HOH D 3 .   ? 10.19899  -17.82297 -1.81360  1.000 31.83306  ? 803 HOH A O    1 
HETATM 6686 O O    . HOH D 3 .   ? 15.32242  -16.00517 -9.86863  1.000 23.99015  ? 804 HOH A O    1 
HETATM 6687 O O    . HOH D 3 .   ? -9.37170  -0.53828  15.10756  1.000 27.18402  ? 805 HOH A O    1 
HETATM 6688 O O    . HOH D 3 .   ? -14.11513 16.29779  31.63524  1.000 41.25993  ? 806 HOH A O    1 
HETATM 6689 O O    . HOH D 3 .   ? 30.12391  6.06280   5.05991   1.000 32.04374  ? 807 HOH A O    1 
HETATM 6690 O O    . HOH D 3 .   ? -8.12981  3.51875   20.24488  1.000 37.09389  ? 808 HOH A O    1 
HETATM 6691 O O    . HOH D 3 .   ? 18.86186  -9.74843  -9.74587  1.000 24.55957  ? 809 HOH A O    1 
HETATM 6692 O O    . HOH D 3 .   ? 3.09490   -11.63076 15.54867  1.000 41.43093  ? 810 HOH A O    1 
HETATM 6693 O O    . HOH D 3 .   ? 8.77133   15.87188  -5.59117  1.000 48.32371  ? 811 HOH A O    1 
HETATM 6694 O O    . HOH D 3 .   ? 14.23905  -11.06040 -24.62897 1.000 43.52727  ? 812 HOH A O    1 
HETATM 6695 O O    . HOH D 3 .   ? 34.10848  6.12814   -3.59534  1.000 43.81956  ? 813 HOH A O    1 
HETATM 6696 O O    . HOH D 3 .   ? 11.88504  15.75400  -7.14542  1.000 40.42159  ? 814 HOH A O    1 
HETATM 6697 O O    . HOH D 3 .   ? 18.38020  11.62687  15.42021  1.000 34.39161  ? 815 HOH A O    1 
HETATM 6698 O O    . HOH D 3 .   ? 3.83821   21.42719  23.13896  1.000 25.64589  ? 816 HOH A O    1 
HETATM 6699 O O    . HOH D 3 .   ? 2.67133   -1.78591  10.73544  1.000 22.13418  ? 817 HOH A O    1 
HETATM 6700 O O    . HOH D 3 .   ? -3.06940  -12.16502 19.81557  1.000 44.64904  ? 818 HOH A O    1 
HETATM 6701 O O    . HOH D 3 .   ? 4.28638   9.87145   -13.03794 1.000 40.12118  ? 819 HOH A O    1 
HETATM 6702 O O    . HOH D 3 .   ? -7.48675  -5.75127  12.58279  1.000 38.68118  ? 820 HOH A O    1 
HETATM 6703 O O    . HOH D 3 .   ? 20.14150  -10.85792 25.56406  1.000 41.65642  ? 821 HOH A O    1 
HETATM 6704 O O    . HOH D 3 .   ? 7.77257   2.80649   -21.59418 1.000 18.18760  ? 822 HOH A O    1 
HETATM 6705 O O    . HOH D 3 .   ? -11.27659 13.25329  34.15820  1.000 29.01859  ? 823 HOH A O    1 
HETATM 6706 O O    . HOH D 3 .   ? 0.76449   -12.47284 11.02710  1.000 36.96120  ? 824 HOH A O    1 
HETATM 6707 O O    . HOH D 3 .   ? 36.74812  -14.94590 0.18903   1.000 52.51830  ? 825 HOH A O    1 
HETATM 6708 O O    . HOH D 3 .   ? 17.44319  12.14142  11.24371  1.000 29.01512  ? 826 HOH A O    1 
HETATM 6709 O O    . HOH D 3 .   ? 4.59153   -13.68123 -6.68761  1.000 33.51576  ? 827 HOH A O    1 
HETATM 6710 O O    . HOH D 3 .   ? -2.05770  5.14435   7.50377   1.000 35.17775  ? 828 HOH A O    1 
HETATM 6711 O O    . HOH D 3 .   ? 7.32410   -13.07240 17.85369  1.000 42.20771  ? 829 HOH A O    1 
HETATM 6712 O O    . HOH D 3 .   ? -8.935    -18.273   30.533    1.000 23.19550  ? 830 HOH A O    1 
HETATM 6713 O O    . HOH D 3 .   ? 30.32097  -4.40936  -13.28168 1.000 45.48796  ? 831 HOH A O    1 
HETATM 6714 O O    . HOH D 3 .   ? -6.16793  8.05418   17.93083  1.000 37.06221  ? 832 HOH A O    1 
HETATM 6715 O O    . HOH D 3 .   ? 13.86992  -4.66724  32.46820  1.000 26.90562  ? 833 HOH A O    1 
HETATM 6716 O O    . HOH D 3 .   ? 19.59443  20.36170  -6.52408  1.000 39.04658  ? 834 HOH A O    1 
HETATM 6717 O O    . HOH D 3 .   ? 31.15092  8.07705   -3.87227  1.000 42.70604  ? 835 HOH A O    1 
HETATM 6718 O O    . HOH D 3 .   ? 5.44762   -9.79946  12.35433  1.000 15.39704  ? 836 HOH A O    1 
HETATM 6719 O O    . HOH D 3 .   ? 25.06986  4.81875   10.08054  1.000 22.15954  ? 837 HOH A O    1 
HETATM 6720 O O    . HOH D 3 .   ? 11.97520  -10.77586 -5.42630  1.000 16.99492  ? 838 HOH A O    1 
HETATM 6721 O O    . HOH D 3 .   ? -2.58714  -0.30853  -0.13882  1.000 49.20941  ? 839 HOH A O    1 
HETATM 6722 O O    . HOH D 3 .   ? -12.10088 -1.22342  32.51084  1.000 33.68307  ? 840 HOH A O    1 
HETATM 6723 O O    . HOH D 3 .   ? 7.46655   21.46630  28.49528  1.000 44.39118  ? 841 HOH A O    1 
HETATM 6724 O O    . HOH D 3 .   ? -3.65217  26.60061  27.79913  1.000 25.98459  ? 842 HOH A O    1 
HETATM 6725 O O    . HOH D 3 .   ? 12.64969  13.47926  9.57518   1.000 37.06381  ? 843 HOH A O    1 
HETATM 6726 O O    . HOH D 3 .   ? 13.27571  -12.34461 32.39451  1.000 45.58723  ? 844 HOH A O    1 
HETATM 6727 O O    . HOH D 3 .   ? 26.83074  -3.10319  10.28059  1.000 30.90472  ? 845 HOH A O    1 
HETATM 6728 O O    . HOH D 3 .   ? 6.544     -16.022   24.753    1.000 44.72785  ? 846 HOH A O    1 
HETATM 6729 O O    . HOH D 3 .   ? 37.57119  -0.31836  -2.04028  1.000 38.87802  ? 847 HOH A O    1 
HETATM 6730 O O    . HOH D 3 .   ? 3.76849   19.14390  10.54548  1.000 43.50365  ? 848 HOH A O    1 
HETATM 6731 O O    . HOH D 3 .   ? 22.24719  7.93792   6.98955   1.000 37.86893  ? 849 HOH A O    1 
HETATM 6732 O O    . HOH D 3 .   ? 20.73302  -11.73202 -10.26732 1.000 36.34984  ? 850 HOH A O    1 
HETATM 6733 O O    . HOH D 3 .   ? 34.59250  -15.05440 4.38058   1.000 42.36570  ? 851 HOH A O    1 
HETATM 6734 O O    . HOH D 3 .   ? -15.29149 6.04049   30.99914  1.000 41.27959  ? 852 HOH A O    1 
HETATM 6735 O O    . HOH D 3 .   ? 13.36069  -16.72823 -20.38916 1.000 30.14598  ? 853 HOH A O    1 
HETATM 6736 O O    . HOH D 3 .   ? 28.94018  -2.97635  -14.01513 1.000 37.62402  ? 854 HOH A O    1 
HETATM 6737 O O    . HOH D 3 .   ? 28.28410  1.55636   15.93450  1.000 51.69320  ? 855 HOH A O    1 
HETATM 6738 O O    . HOH D 3 .   ? 6.26521   8.15707   8.12923   1.000 27.43326  ? 856 HOH A O    1 
HETATM 6739 O O    . HOH D 3 .   ? -0.03977  6.25275   -8.32031  1.000 42.82784  ? 857 HOH A O    1 
HETATM 6740 O O    . HOH D 3 .   ? -9.796    -11.045   46.772    1.000 29.61838  ? 858 HOH A O    1 
HETATM 6741 O O    . HOH D 3 .   ? -6.61974  -9.43021  11.51533  1.000 43.24708  ? 859 HOH A O    1 
HETATM 6742 O O    . HOH D 3 .   ? 0.89149   -2.54006  2.59814   1.000 30.90976  ? 860 HOH A O    1 
HETATM 6743 O O    . HOH D 3 .   ? 12.32593  13.69407  1.24308   1.000 42.08649  ? 861 HOH A O    1 
HETATM 6744 O O    . HOH D 3 .   ? 1.99092   -8.57582  -14.39371 1.000 45.84918  ? 862 HOH A O    1 
HETATM 6745 O O    . HOH D 3 .   ? -4.58902  -12.70463 22.41777  1.000 40.31902  ? 863 HOH A O    1 
HETATM 6746 O O    . HOH D 3 .   ? 14.68001  -21.75972 -15.67097 1.000 39.09639  ? 864 HOH A O    1 
HETATM 6747 O O    . HOH D 3 .   ? 1.66458   -15.00760 27.33628  1.000 34.36305  ? 865 HOH A O    1 
HETATM 6748 O O    . HOH D 3 .   ? 4.59305   -10.55325 -12.67955 1.000 40.93565  ? 866 HOH A O    1 
HETATM 6749 O O    . HOH D 3 .   ? 5.55921   -5.40605  -19.58579 1.000 35.92842  ? 867 HOH A O    1 
HETATM 6750 O O    . HOH D 3 .   ? -11.03987 14.47748  25.12287  1.000 35.74469  ? 868 HOH A O    1 
HETATM 6751 O O    . HOH D 3 .   ? 34.513    -16.396   -2.415    1.000 51.70156  ? 869 HOH A O    1 
HETATM 6752 O O    . HOH D 3 .   ? -1.94777  -13.51334 13.65628  1.000 30.06724  ? 870 HOH A O    1 
HETATM 6753 O O    . HOH D 3 .   ? -2.06598  -9.99397  -4.32330  1.000 39.84908  ? 871 HOH A O    1 
HETATM 6754 O O    . HOH D 3 .   ? 33.55199  -15.53669 6.30209   1.000 42.99911  ? 872 HOH A O    1 
HETATM 6755 O O    . HOH D 3 .   ? 34.12796  -10.78701 -0.78584  1.000 38.54226  ? 873 HOH A O    1 
HETATM 6756 O O    . HOH D 3 .   ? 15.62902  10.82075  30.31885  1.000 42.43142  ? 874 HOH A O    1 
HETATM 6757 O O    . HOH D 3 .   ? 9.71686   2.24259   34.53185  1.000 16.79955  ? 875 HOH A O    1 
HETATM 6758 O O    . HOH D 3 .   ? 11.72306  19.82765  27.83020  1.000 43.80759  ? 876 HOH A O    1 
HETATM 6759 O O    . HOH D 3 .   ? 10.123    -13.790   29.376    1.000 46.32167  ? 877 HOH A O    1 
HETATM 6760 O O    . HOH D 3 .   ? 6.83049   13.13343  -3.09187  1.000 38.30381  ? 878 HOH A O    1 
HETATM 6761 O O    . HOH D 3 .   ? 3.58491   -13.02918 27.12868  1.000 48.06601  ? 879 HOH A O    1 
HETATM 6762 O O    . HOH D 3 .   ? 3.98320   -11.65224 11.25508  1.000 31.66291  ? 880 HOH A O    1 
HETATM 6763 O O    . HOH D 3 .   ? -9.44463  -4.54764  16.80347  1.000 48.70326  ? 881 HOH A O    1 
HETATM 6764 O O    . HOH D 3 .   ? 8.335     -22.863   -19.021   1.000 40.32584  ? 882 HOH A O    1 
HETATM 6765 O O    . HOH D 3 .   ? 5.65730   -11.10608 14.98118  1.000 29.22977  ? 883 HOH A O    1 
HETATM 6766 O O    . HOH D 3 .   ? -6.02121  25.50718  26.77847  1.000 26.00882  ? 884 HOH A O    1 
HETATM 6767 O O    . HOH D 3 .   ? -0.36762  0.16735   2.96140   1.000 48.26149  ? 885 HOH A O    1 
HETATM 6768 O O    . HOH D 3 .   ? 25.264    -16.490   13.325    1.000 44.74234  ? 886 HOH A O    1 
HETATM 6769 O O    . HOH D 3 .   ? -8.49698  -2.69793  17.01277  1.000 33.84620  ? 887 HOH A O    1 
HETATM 6770 O O    . HOH D 3 .   ? -11.252   -2.577    -1.608    1.000 51.69013  ? 888 HOH A O    1 
HETATM 6771 O O    . HOH D 3 .   ? 26.18820  14.21267  -14.21054 1.000 47.96176  ? 889 HOH A O    1 
HETATM 6772 O O    . HOH D 3 .   ? -5.13083  22.50282  20.32310  1.000 38.86296  ? 890 HOH A O    1 
HETATM 6773 O O    . HOH D 3 .   ? 16.02620  -2.95632  33.17193  1.000 31.71815  ? 891 HOH A O    1 
HETATM 6774 O O    . HOH D 3 .   ? -12.299   25.284    27.385    1.000 42.32737  ? 892 HOH A O    1 
HETATM 6775 O O    . HOH D 3 .   ? 14.73775  13.96492  3.40714   1.000 33.76055  ? 893 HOH A O    1 
HETATM 6776 O O    . HOH D 3 .   ? 5.40863   23.19333  24.15502  1.000 42.55907  ? 894 HOH A O    1 
HETATM 6777 O O    . HOH D 3 .   ? -4.40978  -1.99493  -0.49421  1.000 44.70121  ? 895 HOH A O    1 
HETATM 6778 O O    . HOH D 3 .   ? -0.93891  -14.15573 10.84550  1.000 46.21778  ? 896 HOH A O    1 
HETATM 6779 O O    . HOH D 3 .   ? 9.687     -4.960    36.419    1.000 24.57268  ? 897 HOH A O    1 
HETATM 6780 O O    . HOH D 3 .   ? 14.31986  9.18610   31.18177  1.000 46.03522  ? 898 HOH A O    1 
HETATM 6781 O O    . HOH D 3 .   ? 16.64016  11.92342  -11.42016 1.000 42.50855  ? 899 HOH A O    1 
HETATM 6782 O O    . HOH D 3 .   ? -0.53401  4.43600   0.39981   1.000 45.37310  ? 900 HOH A O    1 
HETATM 6783 O O    . HOH D 3 .   ? -0.89428  5.53475   2.35462   1.000 38.37229  ? 901 HOH A O    1 
HETATM 6784 O O    . HOH D 3 .   ? 2.51420   3.12750   44.10474  1.000 46.21256  ? 902 HOH A O    1 
HETATM 6785 O O    . HOH D 3 .   ? 16.12247  10.11947  -17.31281 1.000 45.69732  ? 903 HOH A O    1 
HETATM 6786 O O    . HOH D 3 .   ? -5.81296  -10.49990 35.89997  1.000 46.55840  ? 904 HOH A O    1 
HETATM 6787 O O    . HOH D 3 .   ? 26.54807  -13.52158 -2.92672  1.000 49.75246  ? 905 HOH A O    1 
HETATM 6788 O O    . HOH D 3 .   ? -7.24848  20.96240  19.60639  1.000 39.81651  ? 906 HOH A O    1 
HETATM 6789 O O    . HOH D 3 .   ? 20.98707  -12.74984 27.27768  1.000 48.97777  ? 907 HOH A O    1 
HETATM 6790 O O    . HOH D 3 .   ? -0.98358  -0.81893  1.03869   1.000 51.20979  ? 908 HOH A O    1 
HETATM 6791 O O    . HOH D 3 .   ? 4.97172   22.94548  17.62039  1.000 37.35745  ? 909 HOH A O    1 
HETATM 6792 O O    . HOH D 3 .   ? 3.24325   -6.43051  -18.60766 1.000 45.49018  ? 910 HOH A O    1 
HETATM 6793 O O    . HOH D 3 .   ? 13.11817  -8.90137  -25.27060 1.000 33.68516  ? 911 HOH A O    1 
HETATM 6794 O O    . HOH D 3 .   ? 15.47970  13.28713  26.14144  1.000 33.55867  ? 912 HOH A O    1 
HETATM 6795 O O    . HOH D 3 .   ? 5.17043   -14.99604 5.22479   1.000 36.26229  ? 913 HOH A O    1 
HETATM 6796 O O    . HOH D 3 .   ? -7.30538  -15.92404 22.97357  1.000 46.50758  ? 914 HOH A O    1 
HETATM 6797 O O    . HOH D 3 .   ? 11.77621  11.05742  9.76599   1.000 26.37377  ? 915 HOH A O    1 
HETATM 6798 O O    . HOH D 3 .   ? 9.17746   6.29486   -24.16096 1.000 40.95062  ? 916 HOH A O    1 
HETATM 6799 O O    . HOH D 3 .   ? 17.40263  8.38545   -17.54201 1.000 41.43597  ? 917 HOH A O    1 
HETATM 6800 O O    . HOH D 3 .   ? 0.989     23.807    23.611    1.000 36.13792  ? 918 HOH A O    1 
HETATM 6801 O O    . HOH D 3 .   ? -2.05398  6.37635   -9.09093  1.000 48.23846  ? 919 HOH A O    1 
HETATM 6802 O O    . HOH D 3 .   ? 10.33098  10.41958  32.57712  1.000 39.26354  ? 920 HOH A O    1 
HETATM 6803 O O    . HOH D 3 .   ? -6.013    16.095    9.330     1.000 39.56553  ? 921 HOH A O    1 
HETATM 6804 O O    . HOH D 3 .   ? 4.441     15.338    -11.793   1.000 40.06046  ? 922 HOH A O    1 
HETATM 6805 O O    . HOH D 3 .   ? 7.65226   5.39683   -21.92175 1.000 29.27063  ? 923 HOH A O    1 
HETATM 6806 O O    . HOH D 3 .   ? 8.51042   13.13510  8.17955   1.000 42.38436  ? 924 HOH A O    1 
HETATM 6807 O O    . HOH D 3 .   ? 5.399     -16.684   27.040    1.000 38.31982  ? 925 HOH A O    1 
HETATM 6808 O O    . HOH D 3 .   ? 15.84724  12.50192  -13.29276 1.000 43.91172  ? 926 HOH A O    1 
HETATM 6809 O O    . HOH D 3 .   ? 2.15602   -13.93501 16.83819  1.000 44.72496  ? 927 HOH A O    1 
HETATM 6810 O O    . HOH D 3 .   ? 23.93222  -12.34841 23.20939  1.000 39.24713  ? 928 HOH A O    1 
HETATM 6811 O O    . HOH D 3 .   ? -8.51673  -4.81585  31.93459  1.000 38.70514  ? 929 HOH A O    1 
HETATM 6812 O O    . HOH D 3 .   ? -9.54663  12.85330  38.84647  1.000 40.67689  ? 930 HOH A O    1 
HETATM 6813 O O    . HOH D 3 .   ? 12.34949  18.77195  14.52120  1.000 47.04242  ? 931 HOH A O    1 
HETATM 6814 O O    . HOH D 3 .   ? -7.93771  -9.24094  31.11149  1.000 45.36053  ? 932 HOH A O    1 
HETATM 6815 O O    . HOH D 3 .   ? 0.19259   5.49800   -3.49901  1.000 48.19912  ? 933 HOH A O    1 
HETATM 6816 O O    . HOH D 3 .   ? -10.94306 -1.36882  30.79178  1.000 51.03785  ? 934 HOH A O    1 
HETATM 6817 O O    . HOH D 3 .   ? -1.77436  -15.18831 24.10598  1.000 32.36759  ? 935 HOH A O    1 
HETATM 6818 O O    . HOH D 3 .   ? 6.884     18.058    -13.568   1.000 37.30596  ? 936 HOH A O    1 
HETATM 6819 O O    . HOH D 3 .   ? 7.29185   -13.48218 14.27783  1.000 41.05565  ? 937 HOH A O    1 
HETATM 6820 O O    . HOH D 3 .   ? -4.41989  -14.83129 13.81407  1.000 33.49337  ? 938 HOH A O    1 
HETATM 6821 O O    . HOH D 3 .   ? -8.61504  -7.55624  32.24723  1.000 44.96723  ? 939 HOH A O    1 
# 
