data_8ZT3
# 
_entry.id   8ZT3 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZT3         pdb_00008zt3 10.2210/pdb8zt3/pdb 
WWPDB D_1300048471 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZT3 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-06 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              abei@mol.f.u-tokyo.ac.jp 
_pdbx_contact_author.name_first         Ikuro 
_pdbx_contact_author.name_last          Abe 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3640-888X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Rui, Z.'  1 ? 
'Mori, T.' 2 ? 
'Abe, I.'  3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                10896 
_citation.page_last                 10896 
_citation.title                     
'Structure-function analysis of carrier protein-dependent 2-sulfamoylacetyl transferase in the biosynthesis of altemicidin.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-55265-z 
_citation.pdbx_database_id_PubMed   39738057 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhu, Y.'      1 ?                   
primary 'Mori, T.'     2 0000-0002-2754-5858 
primary 'Karasawa, M.' 3 ?                   
primary 'Shirai, K.'   4 ?                   
primary 'Cheng, W.'    5 ?                   
primary 'Terada, T.'   6 0000-0002-7091-0646 
primary 'Awakawa, T.'  7 0000-0003-2575-3175 
primary 'Abe, I.'      8 0000-0002-3640-888X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'GNAT family transferase' 22243.867 6   ? ? ? ? 
2 non-polymer nat 'CHLORIDE ION'            35.453    1   ? ? ? ? 
3 water       nat water                     18.015    184 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGLVPRGSHMADTRIPAGEATAAWQWEVSRDTGEVHAMLCACDAHQAAASGTSAPARRMETTEHRVRSG
SVHLLRHDGRPAGMFTLTWDPPFAADEGAFPPAERPLYLSRLAVAPEWLTGGSLVGLRCLRRAIETAAQAGGDALRSEAN
PDLSATRSLLDILGFVQHGPTLSDGQGRRRVHLHKSLRPASPGPGGED
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGLVPRGSHMADTRIPAGEATAAWQWEVSRDTGEVHAMLCACDAHQAAASGTSAPARRMETTEHRVRSG
SVHLLRHDGRPAGMFTLTWDPPFAADEGAFPPAERPLYLSRLAVAPEWLTGGSLVGLRCLRRAIETAAQAGGDALRSEAN
PDLSATRSLLDILGFVQHGPTLSDGQGRRRVHLHKSLRPASPGPGGED
;
_entity_poly.pdbx_strand_id                 D,A,B,C,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'CHLORIDE ION' CL  
3 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  ALA n 
1 23  ASP n 
1 24  THR n 
1 25  ARG n 
1 26  ILE n 
1 27  PRO n 
1 28  ALA n 
1 29  GLY n 
1 30  GLU n 
1 31  ALA n 
1 32  THR n 
1 33  ALA n 
1 34  ALA n 
1 35  TRP n 
1 36  GLN n 
1 37  TRP n 
1 38  GLU n 
1 39  VAL n 
1 40  SER n 
1 41  ARG n 
1 42  ASP n 
1 43  THR n 
1 44  GLY n 
1 45  GLU n 
1 46  VAL n 
1 47  HIS n 
1 48  ALA n 
1 49  MET n 
1 50  LEU n 
1 51  CYS n 
1 52  ALA n 
1 53  CYS n 
1 54  ASP n 
1 55  ALA n 
1 56  HIS n 
1 57  GLN n 
1 58  ALA n 
1 59  ALA n 
1 60  ALA n 
1 61  SER n 
1 62  GLY n 
1 63  THR n 
1 64  SER n 
1 65  ALA n 
1 66  PRO n 
1 67  ALA n 
1 68  ARG n 
1 69  ARG n 
1 70  MET n 
1 71  GLU n 
1 72  THR n 
1 73  THR n 
1 74  GLU n 
1 75  HIS n 
1 76  ARG n 
1 77  VAL n 
1 78  ARG n 
1 79  SER n 
1 80  GLY n 
1 81  SER n 
1 82  VAL n 
1 83  HIS n 
1 84  LEU n 
1 85  LEU n 
1 86  ARG n 
1 87  HIS n 
1 88  ASP n 
1 89  GLY n 
1 90  ARG n 
1 91  PRO n 
1 92  ALA n 
1 93  GLY n 
1 94  MET n 
1 95  PHE n 
1 96  THR n 
1 97  LEU n 
1 98  THR n 
1 99  TRP n 
1 100 ASP n 
1 101 PRO n 
1 102 PRO n 
1 103 PHE n 
1 104 ALA n 
1 105 ALA n 
1 106 ASP n 
1 107 GLU n 
1 108 GLY n 
1 109 ALA n 
1 110 PHE n 
1 111 PRO n 
1 112 PRO n 
1 113 ALA n 
1 114 GLU n 
1 115 ARG n 
1 116 PRO n 
1 117 LEU n 
1 118 TYR n 
1 119 LEU n 
1 120 SER n 
1 121 ARG n 
1 122 LEU n 
1 123 ALA n 
1 124 VAL n 
1 125 ALA n 
1 126 PRO n 
1 127 GLU n 
1 128 TRP n 
1 129 LEU n 
1 130 THR n 
1 131 GLY n 
1 132 GLY n 
1 133 SER n 
1 134 LEU n 
1 135 VAL n 
1 136 GLY n 
1 137 LEU n 
1 138 ARG n 
1 139 CYS n 
1 140 LEU n 
1 141 ARG n 
1 142 ARG n 
1 143 ALA n 
1 144 ILE n 
1 145 GLU n 
1 146 THR n 
1 147 ALA n 
1 148 ALA n 
1 149 GLN n 
1 150 ALA n 
1 151 GLY n 
1 152 GLY n 
1 153 ASP n 
1 154 ALA n 
1 155 LEU n 
1 156 ARG n 
1 157 SER n 
1 158 GLU n 
1 159 ALA n 
1 160 ASN n 
1 161 PRO n 
1 162 ASP n 
1 163 LEU n 
1 164 SER n 
1 165 ALA n 
1 166 THR n 
1 167 ARG n 
1 168 SER n 
1 169 LEU n 
1 170 LEU n 
1 171 ASP n 
1 172 ILE n 
1 173 LEU n 
1 174 GLY n 
1 175 PHE n 
1 176 VAL n 
1 177 GLN n 
1 178 HIS n 
1 179 GLY n 
1 180 PRO n 
1 181 THR n 
1 182 LEU n 
1 183 SER n 
1 184 ASP n 
1 185 GLY n 
1 186 GLN n 
1 187 GLY n 
1 188 ARG n 
1 189 ARG n 
1 190 ARG n 
1 191 VAL n 
1 192 HIS n 
1 193 LEU n 
1 194 HIS n 
1 195 LYS n 
1 196 SER n 
1 197 LEU n 
1 198 ARG n 
1 199 PRO n 
1 200 ALA n 
1 201 SER n 
1 202 PRO n 
1 203 GLY n 
1 204 PRO n 
1 205 GLY n 
1 206 GLY n 
1 207 GLU n 
1 208 ASP n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   208 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 sbzI 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptomyces sp.' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1931 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION'  ? 'Cl -1'          35.453  
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -19 ?   ?   ?   D . n 
A 1 2   GLY 2   -18 ?   ?   ?   D . n 
A 1 3   SER 3   -17 ?   ?   ?   D . n 
A 1 4   SER 4   -16 ?   ?   ?   D . n 
A 1 5   HIS 5   -15 ?   ?   ?   D . n 
A 1 6   HIS 6   -14 ?   ?   ?   D . n 
A 1 7   HIS 7   -13 ?   ?   ?   D . n 
A 1 8   HIS 8   -12 ?   ?   ?   D . n 
A 1 9   HIS 9   -11 ?   ?   ?   D . n 
A 1 10  HIS 10  -10 ?   ?   ?   D . n 
A 1 11  SER 11  -9  ?   ?   ?   D . n 
A 1 12  SER 12  -8  ?   ?   ?   D . n 
A 1 13  GLY 13  -7  ?   ?   ?   D . n 
A 1 14  LEU 14  -6  ?   ?   ?   D . n 
A 1 15  VAL 15  -5  ?   ?   ?   D . n 
A 1 16  PRO 16  -4  ?   ?   ?   D . n 
A 1 17  ARG 17  -3  ?   ?   ?   D . n 
A 1 18  GLY 18  -2  ?   ?   ?   D . n 
A 1 19  SER 19  -1  ?   ?   ?   D . n 
A 1 20  HIS 20  0   ?   ?   ?   D . n 
A 1 21  MET 21  1   ?   ?   ?   D . n 
A 1 22  ALA 22  2   ?   ?   ?   D . n 
A 1 23  ASP 23  3   3   ASP ASP D . n 
A 1 24  THR 24  4   4   THR THR D . n 
A 1 25  ARG 25  5   5   ARG ARG D . n 
A 1 26  ILE 26  6   6   ILE ILE D . n 
A 1 27  PRO 27  7   7   PRO PRO D . n 
A 1 28  ALA 28  8   8   ALA ALA D . n 
A 1 29  GLY 29  9   9   GLY GLY D . n 
A 1 30  GLU 30  10  10  GLU GLU D . n 
A 1 31  ALA 31  11  11  ALA ALA D . n 
A 1 32  THR 32  12  12  THR THR D . n 
A 1 33  ALA 33  13  13  ALA ALA D . n 
A 1 34  ALA 34  14  14  ALA ALA D . n 
A 1 35  TRP 35  15  15  TRP TRP D . n 
A 1 36  GLN 36  16  16  GLN GLN D . n 
A 1 37  TRP 37  17  17  TRP TRP D . n 
A 1 38  GLU 38  18  18  GLU GLU D . n 
A 1 39  VAL 39  19  19  VAL VAL D . n 
A 1 40  SER 40  20  20  SER SER D . n 
A 1 41  ARG 41  21  21  ARG ARG D . n 
A 1 42  ASP 42  22  22  ASP ASP D . n 
A 1 43  THR 43  23  23  THR THR D . n 
A 1 44  GLY 44  24  24  GLY GLY D . n 
A 1 45  GLU 45  25  25  GLU GLU D . n 
A 1 46  VAL 46  26  26  VAL VAL D . n 
A 1 47  HIS 47  27  27  HIS HIS D . n 
A 1 48  ALA 48  28  28  ALA ALA D . n 
A 1 49  MET 49  29  29  MET MET D . n 
A 1 50  LEU 50  30  30  LEU LEU D . n 
A 1 51  CYS 51  31  31  CYS CYS D . n 
A 1 52  ALA 52  32  32  ALA ALA D . n 
A 1 53  CYS 53  33  33  CYS CYS D . n 
A 1 54  ASP 54  34  34  ASP ASP D . n 
A 1 55  ALA 55  35  35  ALA ALA D . n 
A 1 56  HIS 56  36  36  HIS HIS D . n 
A 1 57  GLN 57  37  37  GLN GLN D . n 
A 1 58  ALA 58  38  38  ALA ALA D . n 
A 1 59  ALA 59  39  39  ALA ALA D . n 
A 1 60  ALA 60  40  40  ALA ALA D . n 
A 1 61  SER 61  41  41  SER SER D . n 
A 1 62  GLY 62  42  42  GLY GLY D . n 
A 1 63  THR 63  43  43  THR THR D . n 
A 1 64  SER 64  44  44  SER SER D . n 
A 1 65  ALA 65  45  45  ALA ALA D . n 
A 1 66  PRO 66  46  46  PRO PRO D . n 
A 1 67  ALA 67  47  47  ALA ALA D . n 
A 1 68  ARG 68  48  48  ARG ARG D . n 
A 1 69  ARG 69  49  49  ARG ARG D . n 
A 1 70  MET 70  50  50  MET MET D . n 
A 1 71  GLU 71  51  51  GLU GLU D . n 
A 1 72  THR 72  52  52  THR THR D . n 
A 1 73  THR 73  53  53  THR THR D . n 
A 1 74  GLU 74  54  54  GLU GLU D . n 
A 1 75  HIS 75  55  55  HIS HIS D . n 
A 1 76  ARG 76  56  56  ARG ARG D . n 
A 1 77  VAL 77  57  57  VAL VAL D . n 
A 1 78  ARG 78  58  58  ARG ARG D . n 
A 1 79  SER 79  59  59  SER SER D . n 
A 1 80  GLY 80  60  60  GLY GLY D . n 
A 1 81  SER 81  61  61  SER SER D . n 
A 1 82  VAL 82  62  62  VAL VAL D . n 
A 1 83  HIS 83  63  63  HIS HIS D . n 
A 1 84  LEU 84  64  64  LEU LEU D . n 
A 1 85  LEU 85  65  65  LEU LEU D . n 
A 1 86  ARG 86  66  66  ARG ARG D . n 
A 1 87  HIS 87  67  67  HIS HIS D . n 
A 1 88  ASP 88  68  68  ASP ASP D . n 
A 1 89  GLY 89  69  69  GLY GLY D . n 
A 1 90  ARG 90  70  70  ARG ARG D . n 
A 1 91  PRO 91  71  71  PRO PRO D . n 
A 1 92  ALA 92  72  72  ALA ALA D . n 
A 1 93  GLY 93  73  73  GLY GLY D . n 
A 1 94  MET 94  74  74  MET MET D . n 
A 1 95  PHE 95  75  75  PHE PHE D . n 
A 1 96  THR 96  76  76  THR THR D . n 
A 1 97  LEU 97  77  77  LEU LEU D . n 
A 1 98  THR 98  78  78  THR THR D . n 
A 1 99  TRP 99  79  79  TRP TRP D . n 
A 1 100 ASP 100 80  80  ASP ASP D . n 
A 1 101 PRO 101 81  81  PRO PRO D . n 
A 1 102 PRO 102 82  82  PRO PRO D . n 
A 1 103 PHE 103 83  83  PHE PHE D . n 
A 1 104 ALA 104 84  84  ALA ALA D . n 
A 1 105 ALA 105 85  85  ALA ALA D . n 
A 1 106 ASP 106 86  86  ASP ASP D . n 
A 1 107 GLU 107 87  87  GLU GLU D . n 
A 1 108 GLY 108 88  88  GLY GLY D . n 
A 1 109 ALA 109 89  89  ALA ALA D . n 
A 1 110 PHE 110 90  90  PHE PHE D . n 
A 1 111 PRO 111 91  91  PRO PRO D . n 
A 1 112 PRO 112 92  92  PRO PRO D . n 
A 1 113 ALA 113 93  93  ALA ALA D . n 
A 1 114 GLU 114 94  94  GLU GLU D . n 
A 1 115 ARG 115 95  95  ARG ARG D . n 
A 1 116 PRO 116 96  96  PRO PRO D . n 
A 1 117 LEU 117 97  97  LEU LEU D . n 
A 1 118 TYR 118 98  98  TYR TYR D . n 
A 1 119 LEU 119 99  99  LEU LEU D . n 
A 1 120 SER 120 100 100 SER SER D . n 
A 1 121 ARG 121 101 101 ARG ARG D . n 
A 1 122 LEU 122 102 102 LEU LEU D . n 
A 1 123 ALA 123 103 103 ALA ALA D . n 
A 1 124 VAL 124 104 104 VAL VAL D . n 
A 1 125 ALA 125 105 105 ALA ALA D . n 
A 1 126 PRO 126 106 106 PRO PRO D . n 
A 1 127 GLU 127 107 107 GLU GLU D . n 
A 1 128 TRP 128 108 108 TRP TRP D . n 
A 1 129 LEU 129 109 109 LEU LEU D . n 
A 1 130 THR 130 110 110 THR THR D . n 
A 1 131 GLY 131 111 111 GLY GLY D . n 
A 1 132 GLY 132 112 112 GLY GLY D . n 
A 1 133 SER 133 113 113 SER SER D . n 
A 1 134 LEU 134 114 114 LEU LEU D . n 
A 1 135 VAL 135 115 115 VAL VAL D . n 
A 1 136 GLY 136 116 116 GLY GLY D . n 
A 1 137 LEU 137 117 117 LEU LEU D . n 
A 1 138 ARG 138 118 118 ARG ARG D . n 
A 1 139 CYS 139 119 119 CYS CYS D . n 
A 1 140 LEU 140 120 120 LEU LEU D . n 
A 1 141 ARG 141 121 121 ARG ARG D . n 
A 1 142 ARG 142 122 122 ARG ARG D . n 
A 1 143 ALA 143 123 123 ALA ALA D . n 
A 1 144 ILE 144 124 124 ILE ILE D . n 
A 1 145 GLU 145 125 125 GLU GLU D . n 
A 1 146 THR 146 126 126 THR THR D . n 
A 1 147 ALA 147 127 127 ALA ALA D . n 
A 1 148 ALA 148 128 128 ALA ALA D . n 
A 1 149 GLN 149 129 129 GLN GLN D . n 
A 1 150 ALA 150 130 130 ALA ALA D . n 
A 1 151 GLY 151 131 131 GLY GLY D . n 
A 1 152 GLY 152 132 132 GLY GLY D . n 
A 1 153 ASP 153 133 133 ASP ASP D . n 
A 1 154 ALA 154 134 134 ALA ALA D . n 
A 1 155 LEU 155 135 135 LEU LEU D . n 
A 1 156 ARG 156 136 136 ARG ARG D . n 
A 1 157 SER 157 137 137 SER SER D . n 
A 1 158 GLU 158 138 138 GLU GLU D . n 
A 1 159 ALA 159 139 139 ALA ALA D . n 
A 1 160 ASN 160 140 140 ASN ASN D . n 
A 1 161 PRO 161 141 141 PRO PRO D . n 
A 1 162 ASP 162 142 142 ASP ASP D . n 
A 1 163 LEU 163 143 143 LEU LEU D . n 
A 1 164 SER 164 144 144 SER SER D . n 
A 1 165 ALA 165 145 145 ALA ALA D . n 
A 1 166 THR 166 146 146 THR THR D . n 
A 1 167 ARG 167 147 147 ARG ARG D . n 
A 1 168 SER 168 148 148 SER SER D . n 
A 1 169 LEU 169 149 149 LEU LEU D . n 
A 1 170 LEU 170 150 150 LEU LEU D . n 
A 1 171 ASP 171 151 151 ASP ASP D . n 
A 1 172 ILE 172 152 152 ILE ILE D . n 
A 1 173 LEU 173 153 153 LEU LEU D . n 
A 1 174 GLY 174 154 154 GLY GLY D . n 
A 1 175 PHE 175 155 155 PHE PHE D . n 
A 1 176 VAL 176 156 156 VAL VAL D . n 
A 1 177 GLN 177 157 157 GLN GLN D . n 
A 1 178 HIS 178 158 158 HIS HIS D . n 
A 1 179 GLY 179 159 159 GLY GLY D . n 
A 1 180 PRO 180 160 160 PRO PRO D . n 
A 1 181 THR 181 161 161 THR THR D . n 
A 1 182 LEU 182 162 162 LEU LEU D . n 
A 1 183 SER 183 163 163 SER SER D . n 
A 1 184 ASP 184 164 164 ASP ASP D . n 
A 1 185 GLY 185 165 165 GLY GLY D . n 
A 1 186 GLN 186 166 166 GLN GLN D . n 
A 1 187 GLY 187 167 167 GLY GLY D . n 
A 1 188 ARG 188 168 168 ARG ARG D . n 
A 1 189 ARG 189 169 169 ARG ARG D . n 
A 1 190 ARG 190 170 170 ARG ARG D . n 
A 1 191 VAL 191 171 171 VAL VAL D . n 
A 1 192 HIS 192 172 172 HIS HIS D . n 
A 1 193 LEU 193 173 173 LEU LEU D . n 
A 1 194 HIS 194 174 174 HIS HIS D . n 
A 1 195 LYS 195 175 175 LYS LYS D . n 
A 1 196 SER 196 176 176 SER SER D . n 
A 1 197 LEU 197 177 177 LEU LEU D . n 
A 1 198 ARG 198 178 ?   ?   ?   D . n 
A 1 199 PRO 199 179 ?   ?   ?   D . n 
A 1 200 ALA 200 180 ?   ?   ?   D . n 
A 1 201 SER 201 181 ?   ?   ?   D . n 
A 1 202 PRO 202 182 ?   ?   ?   D . n 
A 1 203 GLY 203 183 ?   ?   ?   D . n 
A 1 204 PRO 204 184 ?   ?   ?   D . n 
A 1 205 GLY 205 185 ?   ?   ?   D . n 
A 1 206 GLY 206 186 ?   ?   ?   D . n 
A 1 207 GLU 207 187 ?   ?   ?   D . n 
A 1 208 ASP 208 188 ?   ?   ?   D . n 
B 1 1   MET 1   -19 ?   ?   ?   A . n 
B 1 2   GLY 2   -18 ?   ?   ?   A . n 
B 1 3   SER 3   -17 ?   ?   ?   A . n 
B 1 4   SER 4   -16 ?   ?   ?   A . n 
B 1 5   HIS 5   -15 ?   ?   ?   A . n 
B 1 6   HIS 6   -14 ?   ?   ?   A . n 
B 1 7   HIS 7   -13 ?   ?   ?   A . n 
B 1 8   HIS 8   -12 ?   ?   ?   A . n 
B 1 9   HIS 9   -11 ?   ?   ?   A . n 
B 1 10  HIS 10  -10 ?   ?   ?   A . n 
B 1 11  SER 11  -9  ?   ?   ?   A . n 
B 1 12  SER 12  -8  ?   ?   ?   A . n 
B 1 13  GLY 13  -7  ?   ?   ?   A . n 
B 1 14  LEU 14  -6  ?   ?   ?   A . n 
B 1 15  VAL 15  -5  ?   ?   ?   A . n 
B 1 16  PRO 16  -4  ?   ?   ?   A . n 
B 1 17  ARG 17  -3  ?   ?   ?   A . n 
B 1 18  GLY 18  -2  ?   ?   ?   A . n 
B 1 19  SER 19  -1  ?   ?   ?   A . n 
B 1 20  HIS 20  0   ?   ?   ?   A . n 
B 1 21  MET 21  1   ?   ?   ?   A . n 
B 1 22  ALA 22  2   ?   ?   ?   A . n 
B 1 23  ASP 23  3   ?   ?   ?   A . n 
B 1 24  THR 24  4   ?   ?   ?   A . n 
B 1 25  ARG 25  5   ?   ?   ?   A . n 
B 1 26  ILE 26  6   ?   ?   ?   A . n 
B 1 27  PRO 27  7   ?   ?   ?   A . n 
B 1 28  ALA 28  8   ?   ?   ?   A . n 
B 1 29  GLY 29  9   ?   ?   ?   A . n 
B 1 30  GLU 30  10  ?   ?   ?   A . n 
B 1 31  ALA 31  11  ?   ?   ?   A . n 
B 1 32  THR 32  12  ?   ?   ?   A . n 
B 1 33  ALA 33  13  ?   ?   ?   A . n 
B 1 34  ALA 34  14  14  ALA ALA A . n 
B 1 35  TRP 35  15  15  TRP TRP A . n 
B 1 36  GLN 36  16  16  GLN GLN A . n 
B 1 37  TRP 37  17  17  TRP TRP A . n 
B 1 38  GLU 38  18  18  GLU GLU A . n 
B 1 39  VAL 39  19  19  VAL VAL A . n 
B 1 40  SER 40  20  20  SER SER A . n 
B 1 41  ARG 41  21  21  ARG ARG A . n 
B 1 42  ASP 42  22  22  ASP ASP A . n 
B 1 43  THR 43  23  23  THR THR A . n 
B 1 44  GLY 44  24  24  GLY GLY A . n 
B 1 45  GLU 45  25  25  GLU GLU A . n 
B 1 46  VAL 46  26  26  VAL VAL A . n 
B 1 47  HIS 47  27  27  HIS HIS A . n 
B 1 48  ALA 48  28  28  ALA ALA A . n 
B 1 49  MET 49  29  29  MET MET A . n 
B 1 50  LEU 50  30  30  LEU LEU A . n 
B 1 51  CYS 51  31  31  CYS CYS A . n 
B 1 52  ALA 52  32  32  ALA ALA A . n 
B 1 53  CYS 53  33  33  CYS CYS A . n 
B 1 54  ASP 54  34  34  ASP ASP A . n 
B 1 55  ALA 55  35  35  ALA ALA A . n 
B 1 56  HIS 56  36  36  HIS HIS A . n 
B 1 57  GLN 57  37  37  GLN GLN A . n 
B 1 58  ALA 58  38  38  ALA ALA A . n 
B 1 59  ALA 59  39  39  ALA ALA A . n 
B 1 60  ALA 60  40  40  ALA ALA A . n 
B 1 61  SER 61  41  41  SER SER A . n 
B 1 62  GLY 62  42  42  GLY GLY A . n 
B 1 63  THR 63  43  43  THR THR A . n 
B 1 64  SER 64  44  44  SER SER A . n 
B 1 65  ALA 65  45  45  ALA ALA A . n 
B 1 66  PRO 66  46  46  PRO PRO A . n 
B 1 67  ALA 67  47  47  ALA ALA A . n 
B 1 68  ARG 68  48  48  ARG ARG A . n 
B 1 69  ARG 69  49  49  ARG ARG A . n 
B 1 70  MET 70  50  50  MET MET A . n 
B 1 71  GLU 71  51  51  GLU GLU A . n 
B 1 72  THR 72  52  52  THR THR A . n 
B 1 73  THR 73  53  53  THR THR A . n 
B 1 74  GLU 74  54  54  GLU GLU A . n 
B 1 75  HIS 75  55  55  HIS HIS A . n 
B 1 76  ARG 76  56  56  ARG ARG A . n 
B 1 77  VAL 77  57  57  VAL VAL A . n 
B 1 78  ARG 78  58  58  ARG ARG A . n 
B 1 79  SER 79  59  59  SER SER A . n 
B 1 80  GLY 80  60  60  GLY GLY A . n 
B 1 81  SER 81  61  61  SER SER A . n 
B 1 82  VAL 82  62  62  VAL VAL A . n 
B 1 83  HIS 83  63  63  HIS HIS A . n 
B 1 84  LEU 84  64  64  LEU LEU A . n 
B 1 85  LEU 85  65  65  LEU LEU A . n 
B 1 86  ARG 86  66  66  ARG ARG A . n 
B 1 87  HIS 87  67  67  HIS HIS A . n 
B 1 88  ASP 88  68  68  ASP ASP A . n 
B 1 89  GLY 89  69  69  GLY GLY A . n 
B 1 90  ARG 90  70  70  ARG ARG A . n 
B 1 91  PRO 91  71  71  PRO PRO A . n 
B 1 92  ALA 92  72  72  ALA ALA A . n 
B 1 93  GLY 93  73  73  GLY GLY A . n 
B 1 94  MET 94  74  74  MET MET A . n 
B 1 95  PHE 95  75  75  PHE PHE A . n 
B 1 96  THR 96  76  76  THR THR A . n 
B 1 97  LEU 97  77  77  LEU LEU A . n 
B 1 98  THR 98  78  78  THR THR A . n 
B 1 99  TRP 99  79  79  TRP TRP A . n 
B 1 100 ASP 100 80  80  ASP ASP A . n 
B 1 101 PRO 101 81  81  PRO PRO A . n 
B 1 102 PRO 102 82  82  PRO PRO A . n 
B 1 103 PHE 103 83  83  PHE PHE A . n 
B 1 104 ALA 104 84  84  ALA ALA A . n 
B 1 105 ALA 105 85  85  ALA ALA A . n 
B 1 106 ASP 106 86  86  ASP ASP A . n 
B 1 107 GLU 107 87  87  GLU GLU A . n 
B 1 108 GLY 108 88  88  GLY GLY A . n 
B 1 109 ALA 109 89  89  ALA ALA A . n 
B 1 110 PHE 110 90  90  PHE PHE A . n 
B 1 111 PRO 111 91  91  PRO PRO A . n 
B 1 112 PRO 112 92  92  PRO PRO A . n 
B 1 113 ALA 113 93  93  ALA ALA A . n 
B 1 114 GLU 114 94  94  GLU GLU A . n 
B 1 115 ARG 115 95  95  ARG ARG A . n 
B 1 116 PRO 116 96  96  PRO PRO A . n 
B 1 117 LEU 117 97  97  LEU LEU A . n 
B 1 118 TYR 118 98  98  TYR TYR A . n 
B 1 119 LEU 119 99  99  LEU LEU A . n 
B 1 120 SER 120 100 100 SER SER A . n 
B 1 121 ARG 121 101 101 ARG ARG A . n 
B 1 122 LEU 122 102 102 LEU LEU A . n 
B 1 123 ALA 123 103 103 ALA ALA A . n 
B 1 124 VAL 124 104 104 VAL VAL A . n 
B 1 125 ALA 125 105 105 ALA ALA A . n 
B 1 126 PRO 126 106 106 PRO PRO A . n 
B 1 127 GLU 127 107 107 GLU GLU A . n 
B 1 128 TRP 128 108 108 TRP TRP A . n 
B 1 129 LEU 129 109 109 LEU LEU A . n 
B 1 130 THR 130 110 110 THR THR A . n 
B 1 131 GLY 131 111 111 GLY GLY A . n 
B 1 132 GLY 132 112 112 GLY GLY A . n 
B 1 133 SER 133 113 113 SER SER A . n 
B 1 134 LEU 134 114 114 LEU LEU A . n 
B 1 135 VAL 135 115 115 VAL VAL A . n 
B 1 136 GLY 136 116 116 GLY GLY A . n 
B 1 137 LEU 137 117 117 LEU LEU A . n 
B 1 138 ARG 138 118 118 ARG ARG A . n 
B 1 139 CYS 139 119 119 CYS CYS A . n 
B 1 140 LEU 140 120 120 LEU LEU A . n 
B 1 141 ARG 141 121 121 ARG ARG A . n 
B 1 142 ARG 142 122 122 ARG ARG A . n 
B 1 143 ALA 143 123 123 ALA ALA A . n 
B 1 144 ILE 144 124 124 ILE ILE A . n 
B 1 145 GLU 145 125 125 GLU GLU A . n 
B 1 146 THR 146 126 126 THR THR A . n 
B 1 147 ALA 147 127 127 ALA ALA A . n 
B 1 148 ALA 148 128 128 ALA ALA A . n 
B 1 149 GLN 149 129 129 GLN GLN A . n 
B 1 150 ALA 150 130 130 ALA ALA A . n 
B 1 151 GLY 151 131 131 GLY GLY A . n 
B 1 152 GLY 152 132 132 GLY GLY A . n 
B 1 153 ASP 153 133 133 ASP ASP A . n 
B 1 154 ALA 154 134 134 ALA ALA A . n 
B 1 155 LEU 155 135 135 LEU LEU A . n 
B 1 156 ARG 156 136 136 ARG ARG A . n 
B 1 157 SER 157 137 137 SER SER A . n 
B 1 158 GLU 158 138 138 GLU GLU A . n 
B 1 159 ALA 159 139 139 ALA ALA A . n 
B 1 160 ASN 160 140 140 ASN ASN A . n 
B 1 161 PRO 161 141 141 PRO PRO A . n 
B 1 162 ASP 162 142 142 ASP ASP A . n 
B 1 163 LEU 163 143 143 LEU LEU A . n 
B 1 164 SER 164 144 144 SER SER A . n 
B 1 165 ALA 165 145 145 ALA ALA A . n 
B 1 166 THR 166 146 146 THR THR A . n 
B 1 167 ARG 167 147 147 ARG ARG A . n 
B 1 168 SER 168 148 148 SER SER A . n 
B 1 169 LEU 169 149 149 LEU LEU A . n 
B 1 170 LEU 170 150 150 LEU LEU A . n 
B 1 171 ASP 171 151 151 ASP ASP A . n 
B 1 172 ILE 172 152 152 ILE ILE A . n 
B 1 173 LEU 173 153 153 LEU LEU A . n 
B 1 174 GLY 174 154 154 GLY GLY A . n 
B 1 175 PHE 175 155 155 PHE PHE A . n 
B 1 176 VAL 176 156 156 VAL VAL A . n 
B 1 177 GLN 177 157 157 GLN GLN A . n 
B 1 178 HIS 178 158 158 HIS HIS A . n 
B 1 179 GLY 179 159 159 GLY GLY A . n 
B 1 180 PRO 180 160 160 PRO PRO A . n 
B 1 181 THR 181 161 161 THR THR A . n 
B 1 182 LEU 182 162 162 LEU LEU A . n 
B 1 183 SER 183 163 163 SER SER A . n 
B 1 184 ASP 184 164 164 ASP ASP A . n 
B 1 185 GLY 185 165 165 GLY GLY A . n 
B 1 186 GLN 186 166 166 GLN GLN A . n 
B 1 187 GLY 187 167 167 GLY GLY A . n 
B 1 188 ARG 188 168 168 ARG ARG A . n 
B 1 189 ARG 189 169 169 ARG ARG A . n 
B 1 190 ARG 190 170 170 ARG ARG A . n 
B 1 191 VAL 191 171 171 VAL VAL A . n 
B 1 192 HIS 192 172 172 HIS HIS A . n 
B 1 193 LEU 193 173 173 LEU LEU A . n 
B 1 194 HIS 194 174 174 HIS HIS A . n 
B 1 195 LYS 195 175 175 LYS LYS A . n 
B 1 196 SER 196 176 176 SER SER A . n 
B 1 197 LEU 197 177 177 LEU LEU A . n 
B 1 198 ARG 198 178 ?   ?   ?   A . n 
B 1 199 PRO 199 179 ?   ?   ?   A . n 
B 1 200 ALA 200 180 ?   ?   ?   A . n 
B 1 201 SER 201 181 ?   ?   ?   A . n 
B 1 202 PRO 202 182 ?   ?   ?   A . n 
B 1 203 GLY 203 183 ?   ?   ?   A . n 
B 1 204 PRO 204 184 ?   ?   ?   A . n 
B 1 205 GLY 205 185 ?   ?   ?   A . n 
B 1 206 GLY 206 186 ?   ?   ?   A . n 
B 1 207 GLU 207 187 ?   ?   ?   A . n 
B 1 208 ASP 208 188 ?   ?   ?   A . n 
C 1 1   MET 1   -19 ?   ?   ?   B . n 
C 1 2   GLY 2   -18 ?   ?   ?   B . n 
C 1 3   SER 3   -17 ?   ?   ?   B . n 
C 1 4   SER 4   -16 ?   ?   ?   B . n 
C 1 5   HIS 5   -15 ?   ?   ?   B . n 
C 1 6   HIS 6   -14 ?   ?   ?   B . n 
C 1 7   HIS 7   -13 ?   ?   ?   B . n 
C 1 8   HIS 8   -12 ?   ?   ?   B . n 
C 1 9   HIS 9   -11 ?   ?   ?   B . n 
C 1 10  HIS 10  -10 ?   ?   ?   B . n 
C 1 11  SER 11  -9  ?   ?   ?   B . n 
C 1 12  SER 12  -8  ?   ?   ?   B . n 
C 1 13  GLY 13  -7  ?   ?   ?   B . n 
C 1 14  LEU 14  -6  ?   ?   ?   B . n 
C 1 15  VAL 15  -5  ?   ?   ?   B . n 
C 1 16  PRO 16  -4  ?   ?   ?   B . n 
C 1 17  ARG 17  -3  ?   ?   ?   B . n 
C 1 18  GLY 18  -2  ?   ?   ?   B . n 
C 1 19  SER 19  -1  ?   ?   ?   B . n 
C 1 20  HIS 20  0   ?   ?   ?   B . n 
C 1 21  MET 21  1   ?   ?   ?   B . n 
C 1 22  ALA 22  2   ?   ?   ?   B . n 
C 1 23  ASP 23  3   ?   ?   ?   B . n 
C 1 24  THR 24  4   ?   ?   ?   B . n 
C 1 25  ARG 25  5   ?   ?   ?   B . n 
C 1 26  ILE 26  6   ?   ?   ?   B . n 
C 1 27  PRO 27  7   ?   ?   ?   B . n 
C 1 28  ALA 28  8   ?   ?   ?   B . n 
C 1 29  GLY 29  9   ?   ?   ?   B . n 
C 1 30  GLU 30  10  ?   ?   ?   B . n 
C 1 31  ALA 31  11  ?   ?   ?   B . n 
C 1 32  THR 32  12  ?   ?   ?   B . n 
C 1 33  ALA 33  13  ?   ?   ?   B . n 
C 1 34  ALA 34  14  14  ALA ALA B . n 
C 1 35  TRP 35  15  15  TRP TRP B . n 
C 1 36  GLN 36  16  16  GLN GLN B . n 
C 1 37  TRP 37  17  17  TRP TRP B . n 
C 1 38  GLU 38  18  18  GLU GLU B . n 
C 1 39  VAL 39  19  19  VAL VAL B . n 
C 1 40  SER 40  20  20  SER SER B . n 
C 1 41  ARG 41  21  21  ARG ARG B . n 
C 1 42  ASP 42  22  22  ASP ASP B . n 
C 1 43  THR 43  23  23  THR THR B . n 
C 1 44  GLY 44  24  24  GLY GLY B . n 
C 1 45  GLU 45  25  25  GLU GLU B . n 
C 1 46  VAL 46  26  26  VAL VAL B . n 
C 1 47  HIS 47  27  27  HIS HIS B . n 
C 1 48  ALA 48  28  28  ALA ALA B . n 
C 1 49  MET 49  29  29  MET MET B . n 
C 1 50  LEU 50  30  30  LEU LEU B . n 
C 1 51  CYS 51  31  31  CYS CYS B . n 
C 1 52  ALA 52  32  32  ALA ALA B . n 
C 1 53  CYS 53  33  33  CYS CYS B . n 
C 1 54  ASP 54  34  34  ASP ASP B . n 
C 1 55  ALA 55  35  35  ALA ALA B . n 
C 1 56  HIS 56  36  36  HIS HIS B . n 
C 1 57  GLN 57  37  37  GLN GLN B . n 
C 1 58  ALA 58  38  38  ALA ALA B . n 
C 1 59  ALA 59  39  39  ALA ALA B . n 
C 1 60  ALA 60  40  40  ALA ALA B . n 
C 1 61  SER 61  41  41  SER SER B . n 
C 1 62  GLY 62  42  42  GLY GLY B . n 
C 1 63  THR 63  43  43  THR THR B . n 
C 1 64  SER 64  44  44  SER SER B . n 
C 1 65  ALA 65  45  45  ALA ALA B . n 
C 1 66  PRO 66  46  46  PRO PRO B . n 
C 1 67  ALA 67  47  47  ALA ALA B . n 
C 1 68  ARG 68  48  48  ARG ARG B . n 
C 1 69  ARG 69  49  49  ARG ARG B . n 
C 1 70  MET 70  50  50  MET MET B . n 
C 1 71  GLU 71  51  51  GLU GLU B . n 
C 1 72  THR 72  52  52  THR THR B . n 
C 1 73  THR 73  53  53  THR THR B . n 
C 1 74  GLU 74  54  54  GLU GLU B . n 
C 1 75  HIS 75  55  55  HIS HIS B . n 
C 1 76  ARG 76  56  56  ARG ARG B . n 
C 1 77  VAL 77  57  57  VAL VAL B . n 
C 1 78  ARG 78  58  58  ARG ARG B . n 
C 1 79  SER 79  59  59  SER SER B . n 
C 1 80  GLY 80  60  60  GLY GLY B . n 
C 1 81  SER 81  61  61  SER SER B . n 
C 1 82  VAL 82  62  62  VAL VAL B . n 
C 1 83  HIS 83  63  63  HIS HIS B . n 
C 1 84  LEU 84  64  64  LEU LEU B . n 
C 1 85  LEU 85  65  65  LEU LEU B . n 
C 1 86  ARG 86  66  66  ARG ARG B . n 
C 1 87  HIS 87  67  67  HIS HIS B . n 
C 1 88  ASP 88  68  68  ASP ASP B . n 
C 1 89  GLY 89  69  69  GLY GLY B . n 
C 1 90  ARG 90  70  70  ARG ARG B . n 
C 1 91  PRO 91  71  71  PRO PRO B . n 
C 1 92  ALA 92  72  72  ALA ALA B . n 
C 1 93  GLY 93  73  73  GLY GLY B . n 
C 1 94  MET 94  74  74  MET MET B . n 
C 1 95  PHE 95  75  75  PHE PHE B . n 
C 1 96  THR 96  76  76  THR THR B . n 
C 1 97  LEU 97  77  77  LEU LEU B . n 
C 1 98  THR 98  78  78  THR THR B . n 
C 1 99  TRP 99  79  79  TRP TRP B . n 
C 1 100 ASP 100 80  80  ASP ASP B . n 
C 1 101 PRO 101 81  81  PRO PRO B . n 
C 1 102 PRO 102 82  82  PRO PRO B . n 
C 1 103 PHE 103 83  83  PHE PHE B . n 
C 1 104 ALA 104 84  84  ALA ALA B . n 
C 1 105 ALA 105 85  85  ALA ALA B . n 
C 1 106 ASP 106 86  86  ASP ASP B . n 
C 1 107 GLU 107 87  87  GLU GLU B . n 
C 1 108 GLY 108 88  88  GLY GLY B . n 
C 1 109 ALA 109 89  89  ALA ALA B . n 
C 1 110 PHE 110 90  90  PHE PHE B . n 
C 1 111 PRO 111 91  91  PRO PRO B . n 
C 1 112 PRO 112 92  92  PRO PRO B . n 
C 1 113 ALA 113 93  93  ALA ALA B . n 
C 1 114 GLU 114 94  94  GLU GLU B . n 
C 1 115 ARG 115 95  95  ARG ARG B . n 
C 1 116 PRO 116 96  96  PRO PRO B . n 
C 1 117 LEU 117 97  97  LEU LEU B . n 
C 1 118 TYR 118 98  98  TYR TYR B . n 
C 1 119 LEU 119 99  99  LEU LEU B . n 
C 1 120 SER 120 100 100 SER SER B . n 
C 1 121 ARG 121 101 101 ARG ARG B . n 
C 1 122 LEU 122 102 102 LEU LEU B . n 
C 1 123 ALA 123 103 103 ALA ALA B . n 
C 1 124 VAL 124 104 104 VAL VAL B . n 
C 1 125 ALA 125 105 105 ALA ALA B . n 
C 1 126 PRO 126 106 106 PRO PRO B . n 
C 1 127 GLU 127 107 107 GLU GLU B . n 
C 1 128 TRP 128 108 108 TRP TRP B . n 
C 1 129 LEU 129 109 109 LEU LEU B . n 
C 1 130 THR 130 110 110 THR THR B . n 
C 1 131 GLY 131 111 111 GLY GLY B . n 
C 1 132 GLY 132 112 112 GLY GLY B . n 
C 1 133 SER 133 113 113 SER SER B . n 
C 1 134 LEU 134 114 114 LEU LEU B . n 
C 1 135 VAL 135 115 115 VAL VAL B . n 
C 1 136 GLY 136 116 116 GLY GLY B . n 
C 1 137 LEU 137 117 117 LEU LEU B . n 
C 1 138 ARG 138 118 118 ARG ARG B . n 
C 1 139 CYS 139 119 119 CYS CYS B . n 
C 1 140 LEU 140 120 120 LEU LEU B . n 
C 1 141 ARG 141 121 121 ARG ARG B . n 
C 1 142 ARG 142 122 122 ARG ARG B . n 
C 1 143 ALA 143 123 123 ALA ALA B . n 
C 1 144 ILE 144 124 124 ILE ILE B . n 
C 1 145 GLU 145 125 125 GLU GLU B . n 
C 1 146 THR 146 126 126 THR THR B . n 
C 1 147 ALA 147 127 127 ALA ALA B . n 
C 1 148 ALA 148 128 128 ALA ALA B . n 
C 1 149 GLN 149 129 129 GLN GLN B . n 
C 1 150 ALA 150 130 130 ALA ALA B . n 
C 1 151 GLY 151 131 131 GLY GLY B . n 
C 1 152 GLY 152 132 132 GLY GLY B . n 
C 1 153 ASP 153 133 133 ASP ASP B . n 
C 1 154 ALA 154 134 134 ALA ALA B . n 
C 1 155 LEU 155 135 135 LEU LEU B . n 
C 1 156 ARG 156 136 136 ARG ARG B . n 
C 1 157 SER 157 137 137 SER SER B . n 
C 1 158 GLU 158 138 138 GLU GLU B . n 
C 1 159 ALA 159 139 139 ALA ALA B . n 
C 1 160 ASN 160 140 140 ASN ASN B . n 
C 1 161 PRO 161 141 141 PRO PRO B . n 
C 1 162 ASP 162 142 142 ASP ASP B . n 
C 1 163 LEU 163 143 143 LEU LEU B . n 
C 1 164 SER 164 144 144 SER SER B . n 
C 1 165 ALA 165 145 145 ALA ALA B . n 
C 1 166 THR 166 146 146 THR THR B . n 
C 1 167 ARG 167 147 147 ARG ARG B . n 
C 1 168 SER 168 148 148 SER SER B . n 
C 1 169 LEU 169 149 149 LEU LEU B . n 
C 1 170 LEU 170 150 150 LEU LEU B . n 
C 1 171 ASP 171 151 151 ASP ASP B . n 
C 1 172 ILE 172 152 152 ILE ILE B . n 
C 1 173 LEU 173 153 153 LEU LEU B . n 
C 1 174 GLY 174 154 154 GLY GLY B . n 
C 1 175 PHE 175 155 155 PHE PHE B . n 
C 1 176 VAL 176 156 156 VAL VAL B . n 
C 1 177 GLN 177 157 157 GLN GLN B . n 
C 1 178 HIS 178 158 158 HIS HIS B . n 
C 1 179 GLY 179 159 159 GLY GLY B . n 
C 1 180 PRO 180 160 160 PRO PRO B . n 
C 1 181 THR 181 161 161 THR THR B . n 
C 1 182 LEU 182 162 162 LEU LEU B . n 
C 1 183 SER 183 163 163 SER SER B . n 
C 1 184 ASP 184 164 164 ASP ASP B . n 
C 1 185 GLY 185 165 165 GLY GLY B . n 
C 1 186 GLN 186 166 166 GLN GLN B . n 
C 1 187 GLY 187 167 167 GLY GLY B . n 
C 1 188 ARG 188 168 168 ARG ARG B . n 
C 1 189 ARG 189 169 169 ARG ARG B . n 
C 1 190 ARG 190 170 170 ARG ARG B . n 
C 1 191 VAL 191 171 171 VAL VAL B . n 
C 1 192 HIS 192 172 172 HIS HIS B . n 
C 1 193 LEU 193 173 173 LEU LEU B . n 
C 1 194 HIS 194 174 174 HIS HIS B . n 
C 1 195 LYS 195 175 175 LYS LYS B . n 
C 1 196 SER 196 176 176 SER SER B . n 
C 1 197 LEU 197 177 177 LEU LEU B . n 
C 1 198 ARG 198 178 178 ARG ARG B . n 
C 1 199 PRO 199 179 ?   ?   ?   B . n 
C 1 200 ALA 200 180 ?   ?   ?   B . n 
C 1 201 SER 201 181 ?   ?   ?   B . n 
C 1 202 PRO 202 182 ?   ?   ?   B . n 
C 1 203 GLY 203 183 ?   ?   ?   B . n 
C 1 204 PRO 204 184 ?   ?   ?   B . n 
C 1 205 GLY 205 185 ?   ?   ?   B . n 
C 1 206 GLY 206 186 ?   ?   ?   B . n 
C 1 207 GLU 207 187 ?   ?   ?   B . n 
C 1 208 ASP 208 188 ?   ?   ?   B . n 
D 1 1   MET 1   -19 ?   ?   ?   C . n 
D 1 2   GLY 2   -18 ?   ?   ?   C . n 
D 1 3   SER 3   -17 ?   ?   ?   C . n 
D 1 4   SER 4   -16 ?   ?   ?   C . n 
D 1 5   HIS 5   -15 ?   ?   ?   C . n 
D 1 6   HIS 6   -14 ?   ?   ?   C . n 
D 1 7   HIS 7   -13 ?   ?   ?   C . n 
D 1 8   HIS 8   -12 ?   ?   ?   C . n 
D 1 9   HIS 9   -11 ?   ?   ?   C . n 
D 1 10  HIS 10  -10 ?   ?   ?   C . n 
D 1 11  SER 11  -9  ?   ?   ?   C . n 
D 1 12  SER 12  -8  ?   ?   ?   C . n 
D 1 13  GLY 13  -7  ?   ?   ?   C . n 
D 1 14  LEU 14  -6  ?   ?   ?   C . n 
D 1 15  VAL 15  -5  ?   ?   ?   C . n 
D 1 16  PRO 16  -4  ?   ?   ?   C . n 
D 1 17  ARG 17  -3  ?   ?   ?   C . n 
D 1 18  GLY 18  -2  ?   ?   ?   C . n 
D 1 19  SER 19  -1  ?   ?   ?   C . n 
D 1 20  HIS 20  0   ?   ?   ?   C . n 
D 1 21  MET 21  1   ?   ?   ?   C . n 
D 1 22  ALA 22  2   ?   ?   ?   C . n 
D 1 23  ASP 23  3   ?   ?   ?   C . n 
D 1 24  THR 24  4   ?   ?   ?   C . n 
D 1 25  ARG 25  5   ?   ?   ?   C . n 
D 1 26  ILE 26  6   ?   ?   ?   C . n 
D 1 27  PRO 27  7   ?   ?   ?   C . n 
D 1 28  ALA 28  8   ?   ?   ?   C . n 
D 1 29  GLY 29  9   ?   ?   ?   C . n 
D 1 30  GLU 30  10  ?   ?   ?   C . n 
D 1 31  ALA 31  11  ?   ?   ?   C . n 
D 1 32  THR 32  12  ?   ?   ?   C . n 
D 1 33  ALA 33  13  ?   ?   ?   C . n 
D 1 34  ALA 34  14  14  ALA ALA C . n 
D 1 35  TRP 35  15  15  TRP TRP C . n 
D 1 36  GLN 36  16  16  GLN GLN C . n 
D 1 37  TRP 37  17  17  TRP TRP C . n 
D 1 38  GLU 38  18  18  GLU GLU C . n 
D 1 39  VAL 39  19  19  VAL VAL C . n 
D 1 40  SER 40  20  20  SER SER C . n 
D 1 41  ARG 41  21  21  ARG ARG C . n 
D 1 42  ASP 42  22  22  ASP ASP C . n 
D 1 43  THR 43  23  23  THR THR C . n 
D 1 44  GLY 44  24  24  GLY GLY C . n 
D 1 45  GLU 45  25  25  GLU GLU C . n 
D 1 46  VAL 46  26  26  VAL VAL C . n 
D 1 47  HIS 47  27  27  HIS HIS C . n 
D 1 48  ALA 48  28  28  ALA ALA C . n 
D 1 49  MET 49  29  29  MET MET C . n 
D 1 50  LEU 50  30  30  LEU LEU C . n 
D 1 51  CYS 51  31  31  CYS CYS C . n 
D 1 52  ALA 52  32  32  ALA ALA C . n 
D 1 53  CYS 53  33  33  CYS CYS C . n 
D 1 54  ASP 54  34  34  ASP ASP C . n 
D 1 55  ALA 55  35  35  ALA ALA C . n 
D 1 56  HIS 56  36  36  HIS HIS C . n 
D 1 57  GLN 57  37  37  GLN GLN C . n 
D 1 58  ALA 58  38  38  ALA ALA C . n 
D 1 59  ALA 59  39  39  ALA ALA C . n 
D 1 60  ALA 60  40  40  ALA ALA C . n 
D 1 61  SER 61  41  41  SER SER C . n 
D 1 62  GLY 62  42  42  GLY GLY C . n 
D 1 63  THR 63  43  43  THR THR C . n 
D 1 64  SER 64  44  44  SER SER C . n 
D 1 65  ALA 65  45  45  ALA ALA C . n 
D 1 66  PRO 66  46  46  PRO PRO C . n 
D 1 67  ALA 67  47  47  ALA ALA C . n 
D 1 68  ARG 68  48  48  ARG ARG C . n 
D 1 69  ARG 69  49  49  ARG ARG C . n 
D 1 70  MET 70  50  50  MET MET C . n 
D 1 71  GLU 71  51  51  GLU GLU C . n 
D 1 72  THR 72  52  52  THR THR C . n 
D 1 73  THR 73  53  53  THR THR C . n 
D 1 74  GLU 74  54  54  GLU GLU C . n 
D 1 75  HIS 75  55  55  HIS HIS C . n 
D 1 76  ARG 76  56  56  ARG ARG C . n 
D 1 77  VAL 77  57  57  VAL VAL C . n 
D 1 78  ARG 78  58  58  ARG ARG C . n 
D 1 79  SER 79  59  59  SER SER C . n 
D 1 80  GLY 80  60  60  GLY GLY C . n 
D 1 81  SER 81  61  61  SER SER C . n 
D 1 82  VAL 82  62  62  VAL VAL C . n 
D 1 83  HIS 83  63  63  HIS HIS C . n 
D 1 84  LEU 84  64  64  LEU LEU C . n 
D 1 85  LEU 85  65  65  LEU LEU C . n 
D 1 86  ARG 86  66  66  ARG ARG C . n 
D 1 87  HIS 87  67  67  HIS HIS C . n 
D 1 88  ASP 88  68  68  ASP ASP C . n 
D 1 89  GLY 89  69  69  GLY GLY C . n 
D 1 90  ARG 90  70  70  ARG ARG C . n 
D 1 91  PRO 91  71  71  PRO PRO C . n 
D 1 92  ALA 92  72  72  ALA ALA C . n 
D 1 93  GLY 93  73  73  GLY GLY C . n 
D 1 94  MET 94  74  74  MET MET C . n 
D 1 95  PHE 95  75  75  PHE PHE C . n 
D 1 96  THR 96  76  76  THR THR C . n 
D 1 97  LEU 97  77  77  LEU LEU C . n 
D 1 98  THR 98  78  78  THR THR C . n 
D 1 99  TRP 99  79  79  TRP TRP C . n 
D 1 100 ASP 100 80  80  ASP ASP C . n 
D 1 101 PRO 101 81  81  PRO PRO C . n 
D 1 102 PRO 102 82  82  PRO PRO C . n 
D 1 103 PHE 103 83  83  PHE PHE C . n 
D 1 104 ALA 104 84  84  ALA ALA C . n 
D 1 105 ALA 105 85  85  ALA ALA C . n 
D 1 106 ASP 106 86  86  ASP ASP C . n 
D 1 107 GLU 107 87  87  GLU GLU C . n 
D 1 108 GLY 108 88  88  GLY GLY C . n 
D 1 109 ALA 109 89  89  ALA ALA C . n 
D 1 110 PHE 110 90  90  PHE PHE C . n 
D 1 111 PRO 111 91  91  PRO PRO C . n 
D 1 112 PRO 112 92  92  PRO PRO C . n 
D 1 113 ALA 113 93  93  ALA ALA C . n 
D 1 114 GLU 114 94  94  GLU GLU C . n 
D 1 115 ARG 115 95  95  ARG ARG C . n 
D 1 116 PRO 116 96  96  PRO PRO C . n 
D 1 117 LEU 117 97  97  LEU LEU C . n 
D 1 118 TYR 118 98  98  TYR TYR C . n 
D 1 119 LEU 119 99  99  LEU LEU C . n 
D 1 120 SER 120 100 100 SER SER C . n 
D 1 121 ARG 121 101 101 ARG ARG C . n 
D 1 122 LEU 122 102 102 LEU LEU C . n 
D 1 123 ALA 123 103 103 ALA ALA C . n 
D 1 124 VAL 124 104 104 VAL VAL C . n 
D 1 125 ALA 125 105 105 ALA ALA C . n 
D 1 126 PRO 126 106 106 PRO PRO C . n 
D 1 127 GLU 127 107 107 GLU GLU C . n 
D 1 128 TRP 128 108 108 TRP TRP C . n 
D 1 129 LEU 129 109 109 LEU LEU C . n 
D 1 130 THR 130 110 110 THR THR C . n 
D 1 131 GLY 131 111 111 GLY GLY C . n 
D 1 132 GLY 132 112 112 GLY GLY C . n 
D 1 133 SER 133 113 113 SER SER C . n 
D 1 134 LEU 134 114 114 LEU LEU C . n 
D 1 135 VAL 135 115 115 VAL VAL C . n 
D 1 136 GLY 136 116 116 GLY GLY C . n 
D 1 137 LEU 137 117 117 LEU LEU C . n 
D 1 138 ARG 138 118 118 ARG ARG C . n 
D 1 139 CYS 139 119 119 CYS CYS C . n 
D 1 140 LEU 140 120 120 LEU LEU C . n 
D 1 141 ARG 141 121 121 ARG ARG C . n 
D 1 142 ARG 142 122 122 ARG ARG C . n 
D 1 143 ALA 143 123 123 ALA ALA C . n 
D 1 144 ILE 144 124 124 ILE ILE C . n 
D 1 145 GLU 145 125 125 GLU GLU C . n 
D 1 146 THR 146 126 126 THR THR C . n 
D 1 147 ALA 147 127 127 ALA ALA C . n 
D 1 148 ALA 148 128 128 ALA ALA C . n 
D 1 149 GLN 149 129 129 GLN GLN C . n 
D 1 150 ALA 150 130 130 ALA ALA C . n 
D 1 151 GLY 151 131 131 GLY GLY C . n 
D 1 152 GLY 152 132 132 GLY GLY C . n 
D 1 153 ASP 153 133 133 ASP ASP C . n 
D 1 154 ALA 154 134 134 ALA ALA C . n 
D 1 155 LEU 155 135 135 LEU LEU C . n 
D 1 156 ARG 156 136 136 ARG ARG C . n 
D 1 157 SER 157 137 137 SER SER C . n 
D 1 158 GLU 158 138 138 GLU GLU C . n 
D 1 159 ALA 159 139 139 ALA ALA C . n 
D 1 160 ASN 160 140 140 ASN ASN C . n 
D 1 161 PRO 161 141 141 PRO PRO C . n 
D 1 162 ASP 162 142 142 ASP ASP C . n 
D 1 163 LEU 163 143 143 LEU LEU C . n 
D 1 164 SER 164 144 144 SER SER C . n 
D 1 165 ALA 165 145 145 ALA ALA C . n 
D 1 166 THR 166 146 146 THR THR C . n 
D 1 167 ARG 167 147 147 ARG ARG C . n 
D 1 168 SER 168 148 148 SER SER C . n 
D 1 169 LEU 169 149 149 LEU LEU C . n 
D 1 170 LEU 170 150 150 LEU LEU C . n 
D 1 171 ASP 171 151 151 ASP ASP C . n 
D 1 172 ILE 172 152 152 ILE ILE C . n 
D 1 173 LEU 173 153 153 LEU LEU C . n 
D 1 174 GLY 174 154 154 GLY GLY C . n 
D 1 175 PHE 175 155 155 PHE PHE C . n 
D 1 176 VAL 176 156 156 VAL VAL C . n 
D 1 177 GLN 177 157 157 GLN GLN C . n 
D 1 178 HIS 178 158 158 HIS HIS C . n 
D 1 179 GLY 179 159 159 GLY GLY C . n 
D 1 180 PRO 180 160 160 PRO PRO C . n 
D 1 181 THR 181 161 161 THR THR C . n 
D 1 182 LEU 182 162 162 LEU LEU C . n 
D 1 183 SER 183 163 163 SER SER C . n 
D 1 184 ASP 184 164 164 ASP ASP C . n 
D 1 185 GLY 185 165 165 GLY GLY C . n 
D 1 186 GLN 186 166 166 GLN GLN C . n 
D 1 187 GLY 187 167 167 GLY GLY C . n 
D 1 188 ARG 188 168 168 ARG ARG C . n 
D 1 189 ARG 189 169 169 ARG ARG C . n 
D 1 190 ARG 190 170 170 ARG ARG C . n 
D 1 191 VAL 191 171 171 VAL VAL C . n 
D 1 192 HIS 192 172 172 HIS HIS C . n 
D 1 193 LEU 193 173 173 LEU LEU C . n 
D 1 194 HIS 194 174 174 HIS HIS C . n 
D 1 195 LYS 195 175 175 LYS LYS C . n 
D 1 196 SER 196 176 176 SER SER C . n 
D 1 197 LEU 197 177 177 LEU LEU C . n 
D 1 198 ARG 198 178 178 ARG ARG C . n 
D 1 199 PRO 199 179 ?   ?   ?   C . n 
D 1 200 ALA 200 180 ?   ?   ?   C . n 
D 1 201 SER 201 181 ?   ?   ?   C . n 
D 1 202 PRO 202 182 ?   ?   ?   C . n 
D 1 203 GLY 203 183 ?   ?   ?   C . n 
D 1 204 PRO 204 184 ?   ?   ?   C . n 
D 1 205 GLY 205 185 ?   ?   ?   C . n 
D 1 206 GLY 206 186 ?   ?   ?   C . n 
D 1 207 GLU 207 187 ?   ?   ?   C . n 
D 1 208 ASP 208 188 ?   ?   ?   C . n 
E 1 1   MET 1   -19 ?   ?   ?   E . n 
E 1 2   GLY 2   -18 ?   ?   ?   E . n 
E 1 3   SER 3   -17 ?   ?   ?   E . n 
E 1 4   SER 4   -16 ?   ?   ?   E . n 
E 1 5   HIS 5   -15 ?   ?   ?   E . n 
E 1 6   HIS 6   -14 ?   ?   ?   E . n 
E 1 7   HIS 7   -13 ?   ?   ?   E . n 
E 1 8   HIS 8   -12 ?   ?   ?   E . n 
E 1 9   HIS 9   -11 ?   ?   ?   E . n 
E 1 10  HIS 10  -10 ?   ?   ?   E . n 
E 1 11  SER 11  -9  ?   ?   ?   E . n 
E 1 12  SER 12  -8  ?   ?   ?   E . n 
E 1 13  GLY 13  -7  ?   ?   ?   E . n 
E 1 14  LEU 14  -6  ?   ?   ?   E . n 
E 1 15  VAL 15  -5  ?   ?   ?   E . n 
E 1 16  PRO 16  -4  ?   ?   ?   E . n 
E 1 17  ARG 17  -3  ?   ?   ?   E . n 
E 1 18  GLY 18  -2  ?   ?   ?   E . n 
E 1 19  SER 19  -1  ?   ?   ?   E . n 
E 1 20  HIS 20  0   ?   ?   ?   E . n 
E 1 21  MET 21  1   ?   ?   ?   E . n 
E 1 22  ALA 22  2   ?   ?   ?   E . n 
E 1 23  ASP 23  3   ?   ?   ?   E . n 
E 1 24  THR 24  4   ?   ?   ?   E . n 
E 1 25  ARG 25  5   ?   ?   ?   E . n 
E 1 26  ILE 26  6   ?   ?   ?   E . n 
E 1 27  PRO 27  7   ?   ?   ?   E . n 
E 1 28  ALA 28  8   ?   ?   ?   E . n 
E 1 29  GLY 29  9   ?   ?   ?   E . n 
E 1 30  GLU 30  10  ?   ?   ?   E . n 
E 1 31  ALA 31  11  ?   ?   ?   E . n 
E 1 32  THR 32  12  ?   ?   ?   E . n 
E 1 33  ALA 33  13  ?   ?   ?   E . n 
E 1 34  ALA 34  14  14  ALA ALA E . n 
E 1 35  TRP 35  15  15  TRP TRP E . n 
E 1 36  GLN 36  16  16  GLN GLN E . n 
E 1 37  TRP 37  17  17  TRP TRP E . n 
E 1 38  GLU 38  18  18  GLU GLU E . n 
E 1 39  VAL 39  19  19  VAL VAL E . n 
E 1 40  SER 40  20  20  SER SER E . n 
E 1 41  ARG 41  21  21  ARG ARG E . n 
E 1 42  ASP 42  22  22  ASP ASP E . n 
E 1 43  THR 43  23  23  THR THR E . n 
E 1 44  GLY 44  24  24  GLY GLY E . n 
E 1 45  GLU 45  25  25  GLU GLU E . n 
E 1 46  VAL 46  26  26  VAL VAL E . n 
E 1 47  HIS 47  27  27  HIS HIS E . n 
E 1 48  ALA 48  28  28  ALA ALA E . n 
E 1 49  MET 49  29  29  MET MET E . n 
E 1 50  LEU 50  30  30  LEU LEU E . n 
E 1 51  CYS 51  31  31  CYS CYS E . n 
E 1 52  ALA 52  32  32  ALA ALA E . n 
E 1 53  CYS 53  33  33  CYS CYS E . n 
E 1 54  ASP 54  34  34  ASP ASP E . n 
E 1 55  ALA 55  35  35  ALA ALA E . n 
E 1 56  HIS 56  36  36  HIS HIS E . n 
E 1 57  GLN 57  37  37  GLN GLN E . n 
E 1 58  ALA 58  38  38  ALA ALA E . n 
E 1 59  ALA 59  39  39  ALA ALA E . n 
E 1 60  ALA 60  40  40  ALA ALA E . n 
E 1 61  SER 61  41  41  SER SER E . n 
E 1 62  GLY 62  42  42  GLY GLY E . n 
E 1 63  THR 63  43  43  THR THR E . n 
E 1 64  SER 64  44  44  SER SER E . n 
E 1 65  ALA 65  45  45  ALA ALA E . n 
E 1 66  PRO 66  46  46  PRO PRO E . n 
E 1 67  ALA 67  47  47  ALA ALA E . n 
E 1 68  ARG 68  48  48  ARG ARG E . n 
E 1 69  ARG 69  49  49  ARG ARG E . n 
E 1 70  MET 70  50  50  MET MET E . n 
E 1 71  GLU 71  51  51  GLU GLU E . n 
E 1 72  THR 72  52  52  THR THR E . n 
E 1 73  THR 73  53  53  THR THR E . n 
E 1 74  GLU 74  54  54  GLU GLU E . n 
E 1 75  HIS 75  55  55  HIS HIS E . n 
E 1 76  ARG 76  56  56  ARG ARG E . n 
E 1 77  VAL 77  57  57  VAL VAL E . n 
E 1 78  ARG 78  58  58  ARG ARG E . n 
E 1 79  SER 79  59  59  SER SER E . n 
E 1 80  GLY 80  60  60  GLY GLY E . n 
E 1 81  SER 81  61  61  SER SER E . n 
E 1 82  VAL 82  62  62  VAL VAL E . n 
E 1 83  HIS 83  63  63  HIS HIS E . n 
E 1 84  LEU 84  64  64  LEU LEU E . n 
E 1 85  LEU 85  65  65  LEU LEU E . n 
E 1 86  ARG 86  66  66  ARG ARG E . n 
E 1 87  HIS 87  67  67  HIS HIS E . n 
E 1 88  ASP 88  68  68  ASP ASP E . n 
E 1 89  GLY 89  69  69  GLY GLY E . n 
E 1 90  ARG 90  70  70  ARG ARG E . n 
E 1 91  PRO 91  71  71  PRO PRO E . n 
E 1 92  ALA 92  72  72  ALA ALA E . n 
E 1 93  GLY 93  73  73  GLY GLY E . n 
E 1 94  MET 94  74  74  MET MET E . n 
E 1 95  PHE 95  75  75  PHE PHE E . n 
E 1 96  THR 96  76  76  THR THR E . n 
E 1 97  LEU 97  77  77  LEU LEU E . n 
E 1 98  THR 98  78  78  THR THR E . n 
E 1 99  TRP 99  79  79  TRP TRP E . n 
E 1 100 ASP 100 80  80  ASP ASP E . n 
E 1 101 PRO 101 81  81  PRO PRO E . n 
E 1 102 PRO 102 82  82  PRO PRO E . n 
E 1 103 PHE 103 83  83  PHE PHE E . n 
E 1 104 ALA 104 84  84  ALA ALA E . n 
E 1 105 ALA 105 85  85  ALA ALA E . n 
E 1 106 ASP 106 86  ?   ?   ?   E . n 
E 1 107 GLU 107 87  ?   ?   ?   E . n 
E 1 108 GLY 108 88  ?   ?   ?   E . n 
E 1 109 ALA 109 89  ?   ?   ?   E . n 
E 1 110 PHE 110 90  90  PHE PHE E . n 
E 1 111 PRO 111 91  91  PRO PRO E . n 
E 1 112 PRO 112 92  92  PRO PRO E . n 
E 1 113 ALA 113 93  93  ALA ALA E . n 
E 1 114 GLU 114 94  94  GLU GLU E . n 
E 1 115 ARG 115 95  95  ARG ARG E . n 
E 1 116 PRO 116 96  96  PRO PRO E . n 
E 1 117 LEU 117 97  97  LEU LEU E . n 
E 1 118 TYR 118 98  98  TYR TYR E . n 
E 1 119 LEU 119 99  99  LEU LEU E . n 
E 1 120 SER 120 100 100 SER SER E . n 
E 1 121 ARG 121 101 101 ARG ARG E . n 
E 1 122 LEU 122 102 102 LEU LEU E . n 
E 1 123 ALA 123 103 103 ALA ALA E . n 
E 1 124 VAL 124 104 104 VAL VAL E . n 
E 1 125 ALA 125 105 105 ALA ALA E . n 
E 1 126 PRO 126 106 106 PRO PRO E . n 
E 1 127 GLU 127 107 107 GLU GLU E . n 
E 1 128 TRP 128 108 108 TRP TRP E . n 
E 1 129 LEU 129 109 109 LEU LEU E . n 
E 1 130 THR 130 110 110 THR THR E . n 
E 1 131 GLY 131 111 ?   ?   ?   E . n 
E 1 132 GLY 132 112 ?   ?   ?   E . n 
E 1 133 SER 133 113 ?   ?   ?   E . n 
E 1 134 LEU 134 114 114 LEU LEU E . n 
E 1 135 VAL 135 115 115 VAL VAL E . n 
E 1 136 GLY 136 116 116 GLY GLY E . n 
E 1 137 LEU 137 117 117 LEU LEU E . n 
E 1 138 ARG 138 118 118 ARG ARG E . n 
E 1 139 CYS 139 119 119 CYS CYS E . n 
E 1 140 LEU 140 120 120 LEU LEU E . n 
E 1 141 ARG 141 121 121 ARG ARG E . n 
E 1 142 ARG 142 122 122 ARG ARG E . n 
E 1 143 ALA 143 123 123 ALA ALA E . n 
E 1 144 ILE 144 124 124 ILE ILE E . n 
E 1 145 GLU 145 125 125 GLU GLU E . n 
E 1 146 THR 146 126 126 THR THR E . n 
E 1 147 ALA 147 127 127 ALA ALA E . n 
E 1 148 ALA 148 128 128 ALA ALA E . n 
E 1 149 GLN 149 129 129 GLN GLN E . n 
E 1 150 ALA 150 130 130 ALA ALA E . n 
E 1 151 GLY 151 131 131 GLY GLY E . n 
E 1 152 GLY 152 132 132 GLY GLY E . n 
E 1 153 ASP 153 133 133 ASP ASP E . n 
E 1 154 ALA 154 134 134 ALA ALA E . n 
E 1 155 LEU 155 135 135 LEU LEU E . n 
E 1 156 ARG 156 136 136 ARG ARG E . n 
E 1 157 SER 157 137 137 SER SER E . n 
E 1 158 GLU 158 138 138 GLU GLU E . n 
E 1 159 ALA 159 139 139 ALA ALA E . n 
E 1 160 ASN 160 140 140 ASN ASN E . n 
E 1 161 PRO 161 141 141 PRO PRO E . n 
E 1 162 ASP 162 142 142 ASP ASP E . n 
E 1 163 LEU 163 143 143 LEU LEU E . n 
E 1 164 SER 164 144 144 SER SER E . n 
E 1 165 ALA 165 145 145 ALA ALA E . n 
E 1 166 THR 166 146 146 THR THR E . n 
E 1 167 ARG 167 147 147 ARG ARG E . n 
E 1 168 SER 168 148 148 SER SER E . n 
E 1 169 LEU 169 149 149 LEU LEU E . n 
E 1 170 LEU 170 150 150 LEU LEU E . n 
E 1 171 ASP 171 151 151 ASP ASP E . n 
E 1 172 ILE 172 152 152 ILE ILE E . n 
E 1 173 LEU 173 153 153 LEU LEU E . n 
E 1 174 GLY 174 154 154 GLY GLY E . n 
E 1 175 PHE 175 155 155 PHE PHE E . n 
E 1 176 VAL 176 156 156 VAL VAL E . n 
E 1 177 GLN 177 157 157 GLN GLN E . n 
E 1 178 HIS 178 158 158 HIS HIS E . n 
E 1 179 GLY 179 159 159 GLY GLY E . n 
E 1 180 PRO 180 160 160 PRO PRO E . n 
E 1 181 THR 181 161 161 THR THR E . n 
E 1 182 LEU 182 162 162 LEU LEU E . n 
E 1 183 SER 183 163 163 SER SER E . n 
E 1 184 ASP 184 164 164 ASP ASP E . n 
E 1 185 GLY 185 165 165 GLY GLY E . n 
E 1 186 GLN 186 166 166 GLN GLN E . n 
E 1 187 GLY 187 167 167 GLY GLY E . n 
E 1 188 ARG 188 168 168 ARG ARG E . n 
E 1 189 ARG 189 169 169 ARG ARG E . n 
E 1 190 ARG 190 170 170 ARG ARG E . n 
E 1 191 VAL 191 171 171 VAL VAL E . n 
E 1 192 HIS 192 172 172 HIS HIS E . n 
E 1 193 LEU 193 173 173 LEU LEU E . n 
E 1 194 HIS 194 174 174 HIS HIS E . n 
E 1 195 LYS 195 175 175 LYS LYS E . n 
E 1 196 SER 196 176 176 SER SER E . n 
E 1 197 LEU 197 177 177 LEU LEU E . n 
E 1 198 ARG 198 178 178 ARG ARG E . n 
E 1 199 PRO 199 179 179 PRO PRO E . n 
E 1 200 ALA 200 180 180 ALA ALA E . n 
E 1 201 SER 201 181 181 SER SER E . n 
E 1 202 PRO 202 182 182 PRO PRO E . n 
E 1 203 GLY 203 183 183 GLY GLY E . n 
E 1 204 PRO 204 184 ?   ?   ?   E . n 
E 1 205 GLY 205 185 ?   ?   ?   E . n 
E 1 206 GLY 206 186 ?   ?   ?   E . n 
E 1 207 GLU 207 187 187 GLU GLU E . n 
E 1 208 ASP 208 188 188 ASP ASP E . n 
F 1 1   MET 1   -19 ?   ?   ?   F . n 
F 1 2   GLY 2   -18 ?   ?   ?   F . n 
F 1 3   SER 3   -17 ?   ?   ?   F . n 
F 1 4   SER 4   -16 ?   ?   ?   F . n 
F 1 5   HIS 5   -15 ?   ?   ?   F . n 
F 1 6   HIS 6   -14 ?   ?   ?   F . n 
F 1 7   HIS 7   -13 ?   ?   ?   F . n 
F 1 8   HIS 8   -12 ?   ?   ?   F . n 
F 1 9   HIS 9   -11 ?   ?   ?   F . n 
F 1 10  HIS 10  -10 ?   ?   ?   F . n 
F 1 11  SER 11  -9  ?   ?   ?   F . n 
F 1 12  SER 12  -8  ?   ?   ?   F . n 
F 1 13  GLY 13  -7  ?   ?   ?   F . n 
F 1 14  LEU 14  -6  ?   ?   ?   F . n 
F 1 15  VAL 15  -5  ?   ?   ?   F . n 
F 1 16  PRO 16  -4  ?   ?   ?   F . n 
F 1 17  ARG 17  -3  ?   ?   ?   F . n 
F 1 18  GLY 18  -2  ?   ?   ?   F . n 
F 1 19  SER 19  -1  ?   ?   ?   F . n 
F 1 20  HIS 20  0   ?   ?   ?   F . n 
F 1 21  MET 21  1   ?   ?   ?   F . n 
F 1 22  ALA 22  2   ?   ?   ?   F . n 
F 1 23  ASP 23  3   ?   ?   ?   F . n 
F 1 24  THR 24  4   ?   ?   ?   F . n 
F 1 25  ARG 25  5   ?   ?   ?   F . n 
F 1 26  ILE 26  6   ?   ?   ?   F . n 
F 1 27  PRO 27  7   ?   ?   ?   F . n 
F 1 28  ALA 28  8   ?   ?   ?   F . n 
F 1 29  GLY 29  9   ?   ?   ?   F . n 
F 1 30  GLU 30  10  ?   ?   ?   F . n 
F 1 31  ALA 31  11  ?   ?   ?   F . n 
F 1 32  THR 32  12  ?   ?   ?   F . n 
F 1 33  ALA 33  13  ?   ?   ?   F . n 
F 1 34  ALA 34  14  14  ALA ALA F . n 
F 1 35  TRP 35  15  15  TRP TRP F . n 
F 1 36  GLN 36  16  16  GLN GLN F . n 
F 1 37  TRP 37  17  17  TRP TRP F . n 
F 1 38  GLU 38  18  18  GLU GLU F . n 
F 1 39  VAL 39  19  19  VAL VAL F . n 
F 1 40  SER 40  20  20  SER SER F . n 
F 1 41  ARG 41  21  21  ARG ARG F . n 
F 1 42  ASP 42  22  22  ASP ASP F . n 
F 1 43  THR 43  23  23  THR THR F . n 
F 1 44  GLY 44  24  24  GLY GLY F . n 
F 1 45  GLU 45  25  25  GLU GLU F . n 
F 1 46  VAL 46  26  26  VAL VAL F . n 
F 1 47  HIS 47  27  27  HIS HIS F . n 
F 1 48  ALA 48  28  28  ALA ALA F . n 
F 1 49  MET 49  29  29  MET MET F . n 
F 1 50  LEU 50  30  30  LEU LEU F . n 
F 1 51  CYS 51  31  31  CYS CYS F . n 
F 1 52  ALA 52  32  32  ALA ALA F . n 
F 1 53  CYS 53  33  33  CYS CYS F . n 
F 1 54  ASP 54  34  34  ASP ASP F . n 
F 1 55  ALA 55  35  35  ALA ALA F . n 
F 1 56  HIS 56  36  36  HIS HIS F . n 
F 1 57  GLN 57  37  37  GLN GLN F . n 
F 1 58  ALA 58  38  38  ALA ALA F . n 
F 1 59  ALA 59  39  39  ALA ALA F . n 
F 1 60  ALA 60  40  ?   ?   ?   F . n 
F 1 61  SER 61  41  ?   ?   ?   F . n 
F 1 62  GLY 62  42  ?   ?   ?   F . n 
F 1 63  THR 63  43  ?   ?   ?   F . n 
F 1 64  SER 64  44  44  SER SER F . n 
F 1 65  ALA 65  45  45  ALA ALA F . n 
F 1 66  PRO 66  46  46  PRO PRO F . n 
F 1 67  ALA 67  47  47  ALA ALA F . n 
F 1 68  ARG 68  48  48  ARG ARG F . n 
F 1 69  ARG 69  49  49  ARG ARG F . n 
F 1 70  MET 70  50  50  MET MET F . n 
F 1 71  GLU 71  51  51  GLU GLU F . n 
F 1 72  THR 72  52  52  THR THR F . n 
F 1 73  THR 73  53  53  THR THR F . n 
F 1 74  GLU 74  54  54  GLU GLU F . n 
F 1 75  HIS 75  55  55  HIS HIS F . n 
F 1 76  ARG 76  56  56  ARG ARG F . n 
F 1 77  VAL 77  57  57  VAL VAL F . n 
F 1 78  ARG 78  58  58  ARG ARG F . n 
F 1 79  SER 79  59  59  SER SER F . n 
F 1 80  GLY 80  60  60  GLY GLY F . n 
F 1 81  SER 81  61  61  SER SER F . n 
F 1 82  VAL 82  62  62  VAL VAL F . n 
F 1 83  HIS 83  63  63  HIS HIS F . n 
F 1 84  LEU 84  64  64  LEU LEU F . n 
F 1 85  LEU 85  65  65  LEU LEU F . n 
F 1 86  ARG 86  66  66  ARG ARG F . n 
F 1 87  HIS 87  67  67  HIS HIS F . n 
F 1 88  ASP 88  68  68  ASP ASP F . n 
F 1 89  GLY 89  69  69  GLY GLY F . n 
F 1 90  ARG 90  70  70  ARG ARG F . n 
F 1 91  PRO 91  71  71  PRO PRO F . n 
F 1 92  ALA 92  72  72  ALA ALA F . n 
F 1 93  GLY 93  73  73  GLY GLY F . n 
F 1 94  MET 94  74  74  MET MET F . n 
F 1 95  PHE 95  75  75  PHE PHE F . n 
F 1 96  THR 96  76  76  THR THR F . n 
F 1 97  LEU 97  77  77  LEU LEU F . n 
F 1 98  THR 98  78  78  THR THR F . n 
F 1 99  TRP 99  79  79  TRP TRP F . n 
F 1 100 ASP 100 80  80  ASP ASP F . n 
F 1 101 PRO 101 81  81  PRO PRO F . n 
F 1 102 PRO 102 82  82  PRO PRO F . n 
F 1 103 PHE 103 83  83  PHE PHE F . n 
F 1 104 ALA 104 84  84  ALA ALA F . n 
F 1 105 ALA 105 85  85  ALA ALA F . n 
F 1 106 ASP 106 86  86  ASP ASP F . n 
F 1 107 GLU 107 87  87  GLU GLU F . n 
F 1 108 GLY 108 88  88  GLY GLY F . n 
F 1 109 ALA 109 89  89  ALA ALA F . n 
F 1 110 PHE 110 90  90  PHE PHE F . n 
F 1 111 PRO 111 91  91  PRO PRO F . n 
F 1 112 PRO 112 92  92  PRO PRO F . n 
F 1 113 ALA 113 93  93  ALA ALA F . n 
F 1 114 GLU 114 94  94  GLU GLU F . n 
F 1 115 ARG 115 95  95  ARG ARG F . n 
F 1 116 PRO 116 96  96  PRO PRO F . n 
F 1 117 LEU 117 97  97  LEU LEU F . n 
F 1 118 TYR 118 98  98  TYR TYR F . n 
F 1 119 LEU 119 99  99  LEU LEU F . n 
F 1 120 SER 120 100 100 SER SER F . n 
F 1 121 ARG 121 101 101 ARG ARG F . n 
F 1 122 LEU 122 102 102 LEU LEU F . n 
F 1 123 ALA 123 103 103 ALA ALA F . n 
F 1 124 VAL 124 104 104 VAL VAL F . n 
F 1 125 ALA 125 105 105 ALA ALA F . n 
F 1 126 PRO 126 106 106 PRO PRO F . n 
F 1 127 GLU 127 107 107 GLU GLU F . n 
F 1 128 TRP 128 108 108 TRP TRP F . n 
F 1 129 LEU 129 109 109 LEU LEU F . n 
F 1 130 THR 130 110 110 THR THR F . n 
F 1 131 GLY 131 111 ?   ?   ?   F . n 
F 1 132 GLY 132 112 ?   ?   ?   F . n 
F 1 133 SER 133 113 113 SER SER F . n 
F 1 134 LEU 134 114 114 LEU LEU F . n 
F 1 135 VAL 135 115 115 VAL VAL F . n 
F 1 136 GLY 136 116 116 GLY GLY F . n 
F 1 137 LEU 137 117 117 LEU LEU F . n 
F 1 138 ARG 138 118 118 ARG ARG F . n 
F 1 139 CYS 139 119 119 CYS CYS F . n 
F 1 140 LEU 140 120 120 LEU LEU F . n 
F 1 141 ARG 141 121 121 ARG ARG F . n 
F 1 142 ARG 142 122 122 ARG ARG F . n 
F 1 143 ALA 143 123 123 ALA ALA F . n 
F 1 144 ILE 144 124 124 ILE ILE F . n 
F 1 145 GLU 145 125 125 GLU GLU F . n 
F 1 146 THR 146 126 126 THR THR F . n 
F 1 147 ALA 147 127 127 ALA ALA F . n 
F 1 148 ALA 148 128 128 ALA ALA F . n 
F 1 149 GLN 149 129 129 GLN GLN F . n 
F 1 150 ALA 150 130 130 ALA ALA F . n 
F 1 151 GLY 151 131 131 GLY GLY F . n 
F 1 152 GLY 152 132 132 GLY GLY F . n 
F 1 153 ASP 153 133 133 ASP ASP F . n 
F 1 154 ALA 154 134 134 ALA ALA F . n 
F 1 155 LEU 155 135 135 LEU LEU F . n 
F 1 156 ARG 156 136 136 ARG ARG F . n 
F 1 157 SER 157 137 137 SER SER F . n 
F 1 158 GLU 158 138 138 GLU GLU F . n 
F 1 159 ALA 159 139 139 ALA ALA F . n 
F 1 160 ASN 160 140 140 ASN ASN F . n 
F 1 161 PRO 161 141 141 PRO PRO F . n 
F 1 162 ASP 162 142 142 ASP ASP F . n 
F 1 163 LEU 163 143 143 LEU LEU F . n 
F 1 164 SER 164 144 144 SER SER F . n 
F 1 165 ALA 165 145 145 ALA ALA F . n 
F 1 166 THR 166 146 146 THR THR F . n 
F 1 167 ARG 167 147 147 ARG ARG F . n 
F 1 168 SER 168 148 148 SER SER F . n 
F 1 169 LEU 169 149 149 LEU LEU F . n 
F 1 170 LEU 170 150 150 LEU LEU F . n 
F 1 171 ASP 171 151 151 ASP ASP F . n 
F 1 172 ILE 172 152 152 ILE ILE F . n 
F 1 173 LEU 173 153 153 LEU LEU F . n 
F 1 174 GLY 174 154 154 GLY GLY F . n 
F 1 175 PHE 175 155 155 PHE PHE F . n 
F 1 176 VAL 176 156 156 VAL VAL F . n 
F 1 177 GLN 177 157 157 GLN GLN F . n 
F 1 178 HIS 178 158 158 HIS HIS F . n 
F 1 179 GLY 179 159 159 GLY GLY F . n 
F 1 180 PRO 180 160 160 PRO PRO F . n 
F 1 181 THR 181 161 161 THR THR F . n 
F 1 182 LEU 182 162 162 LEU LEU F . n 
F 1 183 SER 183 163 163 SER SER F . n 
F 1 184 ASP 184 164 ?   ?   ?   F . n 
F 1 185 GLY 185 165 ?   ?   ?   F . n 
F 1 186 GLN 186 166 ?   ?   ?   F . n 
F 1 187 GLY 187 167 ?   ?   ?   F . n 
F 1 188 ARG 188 168 ?   ?   ?   F . n 
F 1 189 ARG 189 169 169 ARG ARG F . n 
F 1 190 ARG 190 170 170 ARG ARG F . n 
F 1 191 VAL 191 171 171 VAL VAL F . n 
F 1 192 HIS 192 172 172 HIS HIS F . n 
F 1 193 LEU 193 173 173 LEU LEU F . n 
F 1 194 HIS 194 174 174 HIS HIS F . n 
F 1 195 LYS 195 175 175 LYS LYS F . n 
F 1 196 SER 196 176 176 SER SER F . n 
F 1 197 LEU 197 177 177 LEU LEU F . n 
F 1 198 ARG 198 178 178 ARG ARG F . n 
F 1 199 PRO 199 179 179 PRO PRO F . n 
F 1 200 ALA 200 180 ?   ?   ?   F . n 
F 1 201 SER 201 181 ?   ?   ?   F . n 
F 1 202 PRO 202 182 ?   ?   ?   F . n 
F 1 203 GLY 203 183 ?   ?   ?   F . n 
F 1 204 PRO 204 184 ?   ?   ?   F . n 
F 1 205 GLY 205 185 ?   ?   ?   F . n 
F 1 206 GLY 206 186 ?   ?   ?   F . n 
F 1 207 GLU 207 187 ?   ?   ?   F . n 
F 1 208 ASP 208 188 ?   ?   ?   F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 CL  1  201 1   CL  CL  B . 
H 3 HOH 1  201 46  HOH HOH D . 
H 3 HOH 2  202 128 HOH HOH D . 
H 3 HOH 3  203 155 HOH HOH D . 
H 3 HOH 4  204 47  HOH HOH D . 
H 3 HOH 5  205 158 HOH HOH D . 
H 3 HOH 6  206 141 HOH HOH D . 
H 3 HOH 7  207 14  HOH HOH D . 
H 3 HOH 8  208 85  HOH HOH D . 
H 3 HOH 9  209 143 HOH HOH D . 
H 3 HOH 10 210 76  HOH HOH D . 
H 3 HOH 11 211 114 HOH HOH D . 
H 3 HOH 12 212 16  HOH HOH D . 
H 3 HOH 13 213 186 HOH HOH D . 
H 3 HOH 14 214 181 HOH HOH D . 
H 3 HOH 15 215 1   HOH HOH D . 
H 3 HOH 16 216 108 HOH HOH D . 
H 3 HOH 17 217 124 HOH HOH D . 
H 3 HOH 18 218 93  HOH HOH D . 
H 3 HOH 19 219 5   HOH HOH D . 
H 3 HOH 20 220 65  HOH HOH D . 
H 3 HOH 21 221 40  HOH HOH D . 
H 3 HOH 22 222 56  HOH HOH D . 
H 3 HOH 23 223 148 HOH HOH D . 
H 3 HOH 24 224 83  HOH HOH D . 
H 3 HOH 25 225 172 HOH HOH D . 
H 3 HOH 26 226 168 HOH HOH D . 
H 3 HOH 27 227 146 HOH HOH D . 
H 3 HOH 28 228 131 HOH HOH D . 
H 3 HOH 29 229 75  HOH HOH D . 
H 3 HOH 30 230 127 HOH HOH D . 
H 3 HOH 31 231 45  HOH HOH D . 
H 3 HOH 32 232 55  HOH HOH D . 
H 3 HOH 33 233 89  HOH HOH D . 
H 3 HOH 34 234 78  HOH HOH D . 
H 3 HOH 35 235 22  HOH HOH D . 
H 3 HOH 36 236 209 HOH HOH D . 
H 3 HOH 37 237 23  HOH HOH D . 
H 3 HOH 38 238 199 HOH HOH D . 
H 3 HOH 39 239 185 HOH HOH D . 
H 3 HOH 40 240 154 HOH HOH D . 
H 3 HOH 41 241 52  HOH HOH D . 
H 3 HOH 42 242 119 HOH HOH D . 
H 3 HOH 43 243 201 HOH HOH D . 
H 3 HOH 44 244 188 HOH HOH D . 
H 3 HOH 45 245 197 HOH HOH D . 
H 3 HOH 46 246 193 HOH HOH D . 
I 3 HOH 1  201 145 HOH HOH A . 
I 3 HOH 2  202 48  HOH HOH A . 
I 3 HOH 3  203 4   HOH HOH A . 
I 3 HOH 4  204 156 HOH HOH A . 
I 3 HOH 5  205 102 HOH HOH A . 
I 3 HOH 6  206 175 HOH HOH A . 
I 3 HOH 7  207 229 HOH HOH A . 
I 3 HOH 8  208 49  HOH HOH A . 
I 3 HOH 9  209 171 HOH HOH A . 
I 3 HOH 10 210 179 HOH HOH A . 
I 3 HOH 11 211 38  HOH HOH A . 
I 3 HOH 12 212 2   HOH HOH A . 
I 3 HOH 13 213 61  HOH HOH A . 
I 3 HOH 14 214 160 HOH HOH A . 
I 3 HOH 15 215 66  HOH HOH A . 
I 3 HOH 16 216 37  HOH HOH A . 
I 3 HOH 17 217 88  HOH HOH A . 
I 3 HOH 18 218 57  HOH HOH A . 
I 3 HOH 19 219 109 HOH HOH A . 
I 3 HOH 20 220 210 HOH HOH A . 
I 3 HOH 21 221 173 HOH HOH A . 
I 3 HOH 22 222 28  HOH HOH A . 
I 3 HOH 23 223 58  HOH HOH A . 
I 3 HOH 24 224 94  HOH HOH A . 
I 3 HOH 25 225 117 HOH HOH A . 
I 3 HOH 26 226 200 HOH HOH A . 
I 3 HOH 27 227 73  HOH HOH A . 
I 3 HOH 28 228 68  HOH HOH A . 
I 3 HOH 29 229 36  HOH HOH A . 
I 3 HOH 30 230 29  HOH HOH A . 
I 3 HOH 31 231 90  HOH HOH A . 
I 3 HOH 32 232 100 HOH HOH A . 
I 3 HOH 33 233 223 HOH HOH A . 
I 3 HOH 34 234 116 HOH HOH A . 
I 3 HOH 35 235 137 HOH HOH A . 
I 3 HOH 36 236 182 HOH HOH A . 
I 3 HOH 37 237 86  HOH HOH A . 
I 3 HOH 38 238 216 HOH HOH A . 
I 3 HOH 39 239 157 HOH HOH A . 
I 3 HOH 40 240 203 HOH HOH A . 
I 3 HOH 41 241 98  HOH HOH A . 
I 3 HOH 42 242 163 HOH HOH A . 
I 3 HOH 43 243 112 HOH HOH A . 
I 3 HOH 44 244 198 HOH HOH A . 
I 3 HOH 45 245 21  HOH HOH A . 
I 3 HOH 46 246 184 HOH HOH A . 
I 3 HOH 47 247 115 HOH HOH A . 
I 3 HOH 48 248 214 HOH HOH A . 
I 3 HOH 49 249 177 HOH HOH A . 
I 3 HOH 50 250 224 HOH HOH A . 
I 3 HOH 51 251 79  HOH HOH A . 
I 3 HOH 52 252 25  HOH HOH A . 
J 3 HOH 1  301 41  HOH HOH B . 
J 3 HOH 2  302 53  HOH HOH B . 
J 3 HOH 3  303 10  HOH HOH B . 
J 3 HOH 4  304 225 HOH HOH B . 
J 3 HOH 5  305 101 HOH HOH B . 
J 3 HOH 6  306 62  HOH HOH B . 
J 3 HOH 7  307 33  HOH HOH B . 
J 3 HOH 8  308 63  HOH HOH B . 
J 3 HOH 9  309 42  HOH HOH B . 
J 3 HOH 10 310 99  HOH HOH B . 
J 3 HOH 11 311 19  HOH HOH B . 
J 3 HOH 12 312 39  HOH HOH B . 
J 3 HOH 13 313 34  HOH HOH B . 
J 3 HOH 14 314 125 HOH HOH B . 
J 3 HOH 15 315 31  HOH HOH B . 
J 3 HOH 16 316 151 HOH HOH B . 
J 3 HOH 17 317 103 HOH HOH B . 
J 3 HOH 18 318 132 HOH HOH B . 
J 3 HOH 19 319 72  HOH HOH B . 
J 3 HOH 20 320 170 HOH HOH B . 
J 3 HOH 21 321 194 HOH HOH B . 
J 3 HOH 22 322 32  HOH HOH B . 
J 3 HOH 23 323 208 HOH HOH B . 
J 3 HOH 24 324 142 HOH HOH B . 
J 3 HOH 25 325 164 HOH HOH B . 
J 3 HOH 26 326 43  HOH HOH B . 
J 3 HOH 27 327 130 HOH HOH B . 
J 3 HOH 28 328 162 HOH HOH B . 
J 3 HOH 29 329 74  HOH HOH B . 
J 3 HOH 30 330 123 HOH HOH B . 
J 3 HOH 31 331 152 HOH HOH B . 
J 3 HOH 32 332 113 HOH HOH B . 
J 3 HOH 33 333 176 HOH HOH B . 
J 3 HOH 34 334 134 HOH HOH B . 
K 3 HOH 1  201 24  HOH HOH C . 
K 3 HOH 2  202 17  HOH HOH C . 
K 3 HOH 3  203 220 HOH HOH C . 
K 3 HOH 4  204 13  HOH HOH C . 
K 3 HOH 5  205 8   HOH HOH C . 
K 3 HOH 6  206 118 HOH HOH C . 
K 3 HOH 7  207 20  HOH HOH C . 
K 3 HOH 8  208 9   HOH HOH C . 
K 3 HOH 9  209 144 HOH HOH C . 
K 3 HOH 10 210 44  HOH HOH C . 
K 3 HOH 11 211 191 HOH HOH C . 
K 3 HOH 12 212 228 HOH HOH C . 
K 3 HOH 13 213 64  HOH HOH C . 
K 3 HOH 14 214 18  HOH HOH C . 
K 3 HOH 15 215 80  HOH HOH C . 
K 3 HOH 16 216 221 HOH HOH C . 
K 3 HOH 17 217 120 HOH HOH C . 
K 3 HOH 18 218 7   HOH HOH C . 
K 3 HOH 19 219 105 HOH HOH C . 
K 3 HOH 20 220 126 HOH HOH C . 
K 3 HOH 21 221 136 HOH HOH C . 
K 3 HOH 22 222 95  HOH HOH C . 
K 3 HOH 23 223 192 HOH HOH C . 
L 3 HOH 1  201 15  HOH HOH E . 
L 3 HOH 2  202 81  HOH HOH E . 
L 3 HOH 3  203 213 HOH HOH E . 
L 3 HOH 4  204 50  HOH HOH E . 
L 3 HOH 5  205 54  HOH HOH E . 
L 3 HOH 6  206 3   HOH HOH E . 
L 3 HOH 7  207 174 HOH HOH E . 
L 3 HOH 8  208 92  HOH HOH E . 
L 3 HOH 9  209 166 HOH HOH E . 
L 3 HOH 10 210 147 HOH HOH E . 
L 3 HOH 11 211 12  HOH HOH E . 
L 3 HOH 12 212 60  HOH HOH E . 
L 3 HOH 13 213 84  HOH HOH E . 
L 3 HOH 14 214 67  HOH HOH E . 
L 3 HOH 15 215 138 HOH HOH E . 
L 3 HOH 16 216 190 HOH HOH E . 
L 3 HOH 17 217 153 HOH HOH E . 
L 3 HOH 18 218 217 HOH HOH E . 
L 3 HOH 19 219 206 HOH HOH E . 
L 3 HOH 20 220 218 HOH HOH E . 
L 3 HOH 21 221 139 HOH HOH E . 
M 3 HOH 1  201 77  HOH HOH F . 
M 3 HOH 2  202 226 HOH HOH F . 
M 3 HOH 3  203 11  HOH HOH F . 
M 3 HOH 4  204 149 HOH HOH F . 
M 3 HOH 5  205 161 HOH HOH F . 
M 3 HOH 6  206 202 HOH HOH F . 
M 3 HOH 7  207 135 HOH HOH F . 
M 3 HOH 8  208 129 HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 F MET 50 ? CG ? F MET 70 CG 
2 1 Y 1 F MET 50 ? SD ? F MET 70 SD 
3 1 Y 1 F MET 50 ? CE ? F MET 70 CE 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.21.1_5286 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           4 
# 
_cell.angle_alpha                  108.543 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.803 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.006 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZT3 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     50.760 
_cell.length_a_esd                 ? 
_cell.length_b                     64.396 
_cell.length_b_esd                 ? 
_cell.length_c                     93.121 
_cell.length_c_esd                 ? 
_cell.volume                       288554.497 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZT3 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            'P 1' 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZT3 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.16 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          43.11 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Tris-HCl, pH 8.0, 0.2 M KSCN, 25% PEG 3350.' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-10-30 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PHOTON FACTORY BEAMLINE BL-1A' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL-1A 
_diffrn_source.pdbx_synchrotron_site       'Photon Factory' 
# 
_reflns.B_iso_Wilson_estimate                          40.81 
_reflns.entry_id                                       8ZT3 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.50 
_reflns.d_resolution_low                               44.28 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     37967 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.2 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.996 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.056 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.50 
_reflns_shell.d_res_low                                     2.60 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.6 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4248 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               3.7 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.888 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          97.7 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.318 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               49.42 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ZT3 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.50 
_refine.ls_d_res_low                             44.28 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     37954 
_refine.ls_number_reflns_R_free                  1984 
_refine.ls_number_reflns_R_work                  35970 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.14 
_refine.ls_percent_reflns_R_free                 5.23 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2038 
_refine.ls_R_factor_R_free                       0.2511 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2012 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.99 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      AlphaFold 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.1860 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3592 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.50 
_refine_hist.d_res_low                        44.28 
_refine_hist.number_atoms_solvent             184 
_refine_hist.number_atoms_total               7737 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7552 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         1 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0023  ? 7742  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.4985  ? 10520 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0355  ? 1143  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0045  ? 1402  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.0085 ? 2818  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.50 2.56  . . 140 2569 97.20 . . . . 0.2899 . . . . . . . . . . . 0.3524 
'X-RAY DIFFRACTION' 2.56 2.63  . . 138 2548 98.28 . . . . 0.2696 . . . . . . . . . . . 0.3517 
'X-RAY DIFFRACTION' 2.63 2.71  . . 145 2556 97.65 . . . . 0.2542 . . . . . . . . . . . 0.3223 
'X-RAY DIFFRACTION' 2.71 2.80  . . 140 2578 97.98 . . . . 0.2369 . . . . . . . . . . . 0.3048 
'X-RAY DIFFRACTION' 2.80 2.90  . . 137 2550 98.42 . . . . 0.2366 . . . . . . . . . . . 0.3135 
'X-RAY DIFFRACTION' 2.90 3.01  . . 143 2594 97.89 . . . . 0.2444 . . . . . . . . . . . 0.2908 
'X-RAY DIFFRACTION' 3.01 3.15  . . 144 2578 98.44 . . . . 0.2552 . . . . . . . . . . . 0.2722 
'X-RAY DIFFRACTION' 3.15 3.32  . . 144 2569 98.83 . . . . 0.2241 . . . . . . . . . . . 0.3113 
'X-RAY DIFFRACTION' 3.32 3.52  . . 144 2563 98.62 . . . . 0.2020 . . . . . . . . . . . 0.2831 
'X-RAY DIFFRACTION' 3.52 3.80  . . 148 2582 98.59 . . . . 0.1925 . . . . . . . . . . . 0.2539 
'X-RAY DIFFRACTION' 3.80 4.18  . . 145 2577 98.30 . . . . 0.1813 . . . . . . . . . . . 0.2231 
'X-RAY DIFFRACTION' 4.18 4.78  . . 140 2557 97.97 . . . . 0.1543 . . . . . . . . . . . 0.1922 
'X-RAY DIFFRACTION' 4.78 6.02  . . 133 2604 98.77 . . . . 0.1772 . . . . . . . . . . . 0.2061 
'X-RAY DIFFRACTION' 6.02 44.28 . . 143 2545 97.11 . . . . 0.1717 . . . . . . . . . . . 0.2029 
# 
_struct.entry_id                     8ZT3 
_struct.title                        'N-acetyltransferase SbzI in the biosynthesis of altemicidin' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZT3 
_struct_keywords.text            
'A general control non-repressible 5 (GCN5)-related N-acetyltransferase, altemicidin, biosynthesis, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A3T0ZHG5_STRSQ 
_struct_ref.pdbx_db_accession          A0A3T0ZHG5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MADTRIPAGEATAAWQWEVSRDTGEVHALLCACDAHQAAASGTSAPARRLETTEHRVRSGSVHLLRHDGRPAGMFTLTWD
PPFAADEGAFPPAERPLYLSRLAVAPEWLTGGSLVGLRCLRRAIETAAQAGGDALRSEANPDLSATRSLLDILGFVQHGP
TLSDGQGRRRVHLHKSLRPASPGPGGED
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZT3 D 21 ? 208 ? A0A3T0ZHG5 1 ? 188 ? 1 188 
2 1 8ZT3 A 21 ? 208 ? A0A3T0ZHG5 1 ? 188 ? 1 188 
3 1 8ZT3 B 21 ? 208 ? A0A3T0ZHG5 1 ? 188 ? 1 188 
4 1 8ZT3 C 21 ? 208 ? A0A3T0ZHG5 1 ? 188 ? 1 188 
5 1 8ZT3 E 21 ? 208 ? A0A3T0ZHG5 1 ? 188 ? 1 188 
6 1 8ZT3 F 21 ? 208 ? A0A3T0ZHG5 1 ? 188 ? 1 188 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8ZT3 MET D 1  ? UNP A0A3T0ZHG5 ?   ?  'initiating methionine' -19 1   
1 8ZT3 GLY D 2  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -18 2   
1 8ZT3 SER D 3  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -17 3   
1 8ZT3 SER D 4  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -16 4   
1 8ZT3 HIS D 5  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -15 5   
1 8ZT3 HIS D 6  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -14 6   
1 8ZT3 HIS D 7  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -13 7   
1 8ZT3 HIS D 8  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -12 8   
1 8ZT3 HIS D 9  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -11 9   
1 8ZT3 HIS D 10 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -10 10  
1 8ZT3 SER D 11 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -9  11  
1 8ZT3 SER D 12 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -8  12  
1 8ZT3 GLY D 13 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -7  13  
1 8ZT3 LEU D 14 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -6  14  
1 8ZT3 VAL D 15 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -5  15  
1 8ZT3 PRO D 16 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -4  16  
1 8ZT3 ARG D 17 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -3  17  
1 8ZT3 GLY D 18 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -2  18  
1 8ZT3 SER D 19 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -1  19  
1 8ZT3 HIS D 20 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        0   20  
1 8ZT3 MET D 49 ? UNP A0A3T0ZHG5 LEU 29 'engineered mutation'   29  21  
1 8ZT3 MET D 70 ? UNP A0A3T0ZHG5 LEU 50 'engineered mutation'   50  22  
2 8ZT3 MET A 1  ? UNP A0A3T0ZHG5 ?   ?  'initiating methionine' -19 23  
2 8ZT3 GLY A 2  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -18 24  
2 8ZT3 SER A 3  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -17 25  
2 8ZT3 SER A 4  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -16 26  
2 8ZT3 HIS A 5  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -15 27  
2 8ZT3 HIS A 6  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -14 28  
2 8ZT3 HIS A 7  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -13 29  
2 8ZT3 HIS A 8  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -12 30  
2 8ZT3 HIS A 9  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -11 31  
2 8ZT3 HIS A 10 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -10 32  
2 8ZT3 SER A 11 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -9  33  
2 8ZT3 SER A 12 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -8  34  
2 8ZT3 GLY A 13 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -7  35  
2 8ZT3 LEU A 14 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -6  36  
2 8ZT3 VAL A 15 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -5  37  
2 8ZT3 PRO A 16 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -4  38  
2 8ZT3 ARG A 17 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -3  39  
2 8ZT3 GLY A 18 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -2  40  
2 8ZT3 SER A 19 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -1  41  
2 8ZT3 HIS A 20 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        0   42  
2 8ZT3 MET A 49 ? UNP A0A3T0ZHG5 LEU 29 'engineered mutation'   29  43  
2 8ZT3 MET A 70 ? UNP A0A3T0ZHG5 LEU 50 'engineered mutation'   50  44  
3 8ZT3 MET B 1  ? UNP A0A3T0ZHG5 ?   ?  'initiating methionine' -19 45  
3 8ZT3 GLY B 2  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -18 46  
3 8ZT3 SER B 3  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -17 47  
3 8ZT3 SER B 4  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -16 48  
3 8ZT3 HIS B 5  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -15 49  
3 8ZT3 HIS B 6  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -14 50  
3 8ZT3 HIS B 7  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -13 51  
3 8ZT3 HIS B 8  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -12 52  
3 8ZT3 HIS B 9  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -11 53  
3 8ZT3 HIS B 10 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -10 54  
3 8ZT3 SER B 11 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -9  55  
3 8ZT3 SER B 12 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -8  56  
3 8ZT3 GLY B 13 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -7  57  
3 8ZT3 LEU B 14 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -6  58  
3 8ZT3 VAL B 15 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -5  59  
3 8ZT3 PRO B 16 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -4  60  
3 8ZT3 ARG B 17 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -3  61  
3 8ZT3 GLY B 18 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -2  62  
3 8ZT3 SER B 19 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -1  63  
3 8ZT3 HIS B 20 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        0   64  
3 8ZT3 MET B 49 ? UNP A0A3T0ZHG5 LEU 29 'engineered mutation'   29  65  
3 8ZT3 MET B 70 ? UNP A0A3T0ZHG5 LEU 50 'engineered mutation'   50  66  
4 8ZT3 MET C 1  ? UNP A0A3T0ZHG5 ?   ?  'initiating methionine' -19 67  
4 8ZT3 GLY C 2  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -18 68  
4 8ZT3 SER C 3  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -17 69  
4 8ZT3 SER C 4  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -16 70  
4 8ZT3 HIS C 5  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -15 71  
4 8ZT3 HIS C 6  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -14 72  
4 8ZT3 HIS C 7  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -13 73  
4 8ZT3 HIS C 8  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -12 74  
4 8ZT3 HIS C 9  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -11 75  
4 8ZT3 HIS C 10 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -10 76  
4 8ZT3 SER C 11 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -9  77  
4 8ZT3 SER C 12 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -8  78  
4 8ZT3 GLY C 13 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -7  79  
4 8ZT3 LEU C 14 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -6  80  
4 8ZT3 VAL C 15 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -5  81  
4 8ZT3 PRO C 16 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -4  82  
4 8ZT3 ARG C 17 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -3  83  
4 8ZT3 GLY C 18 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -2  84  
4 8ZT3 SER C 19 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -1  85  
4 8ZT3 HIS C 20 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        0   86  
4 8ZT3 MET C 49 ? UNP A0A3T0ZHG5 LEU 29 'engineered mutation'   29  87  
4 8ZT3 MET C 70 ? UNP A0A3T0ZHG5 LEU 50 'engineered mutation'   50  88  
5 8ZT3 MET E 1  ? UNP A0A3T0ZHG5 ?   ?  'initiating methionine' -19 89  
5 8ZT3 GLY E 2  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -18 90  
5 8ZT3 SER E 3  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -17 91  
5 8ZT3 SER E 4  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -16 92  
5 8ZT3 HIS E 5  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -15 93  
5 8ZT3 HIS E 6  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -14 94  
5 8ZT3 HIS E 7  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -13 95  
5 8ZT3 HIS E 8  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -12 96  
5 8ZT3 HIS E 9  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -11 97  
5 8ZT3 HIS E 10 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -10 98  
5 8ZT3 SER E 11 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -9  99  
5 8ZT3 SER E 12 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -8  100 
5 8ZT3 GLY E 13 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -7  101 
5 8ZT3 LEU E 14 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -6  102 
5 8ZT3 VAL E 15 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -5  103 
5 8ZT3 PRO E 16 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -4  104 
5 8ZT3 ARG E 17 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -3  105 
5 8ZT3 GLY E 18 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -2  106 
5 8ZT3 SER E 19 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -1  107 
5 8ZT3 HIS E 20 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        0   108 
5 8ZT3 MET E 49 ? UNP A0A3T0ZHG5 LEU 29 'engineered mutation'   29  109 
5 8ZT3 MET E 70 ? UNP A0A3T0ZHG5 LEU 50 'engineered mutation'   50  110 
6 8ZT3 MET F 1  ? UNP A0A3T0ZHG5 ?   ?  'initiating methionine' -19 111 
6 8ZT3 GLY F 2  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -18 112 
6 8ZT3 SER F 3  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -17 113 
6 8ZT3 SER F 4  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -16 114 
6 8ZT3 HIS F 5  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -15 115 
6 8ZT3 HIS F 6  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -14 116 
6 8ZT3 HIS F 7  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -13 117 
6 8ZT3 HIS F 8  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -12 118 
6 8ZT3 HIS F 9  ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -11 119 
6 8ZT3 HIS F 10 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -10 120 
6 8ZT3 SER F 11 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -9  121 
6 8ZT3 SER F 12 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -8  122 
6 8ZT3 GLY F 13 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -7  123 
6 8ZT3 LEU F 14 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -6  124 
6 8ZT3 VAL F 15 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -5  125 
6 8ZT3 PRO F 16 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -4  126 
6 8ZT3 ARG F 17 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -3  127 
6 8ZT3 GLY F 18 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -2  128 
6 8ZT3 SER F 19 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        -1  129 
6 8ZT3 HIS F 20 ? UNP A0A3T0ZHG5 ?   ?  'expression tag'        0   130 
6 8ZT3 MET F 49 ? UNP A0A3T0ZHG5 LEU 29 'engineered mutation'   29  131 
6 8ZT3 MET F 70 ? UNP A0A3T0ZHG5 LEU 50 'engineered mutation'   50  132 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
4 author_defined_assembly ? monomeric 1 
5 author_defined_assembly ? monomeric 1 
6 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,H   
2 1 B,I   
3 1 C,G,J 
4 1 D,K   
5 1 E,L   
6 1 F,M   
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 28  ? ALA A 34  ? ALA D 8   ALA D 14  1 ? 7  
HELX_P HELX_P2  AA2 ASP A 42  ? GLY A 62  ? ASP D 22  GLY D 42  1 ? 21 
HELX_P HELX_P3  AA3 ARG A 69  ? SER A 79  ? ARG D 49  SER D 59  1 ? 11 
HELX_P HELX_P4  AA4 PRO A 126 ? LEU A 129 ? PRO D 106 LEU D 109 5 ? 4  
HELX_P HELX_P5  AA5 LEU A 134 ? ALA A 150 ? LEU D 114 ALA D 130 1 ? 17 
HELX_P HELX_P6  AA6 LEU A 163 ? LEU A 173 ? LEU D 143 LEU D 153 1 ? 11 
HELX_P HELX_P7  AA7 ASP B 42  ? GLY B 62  ? ASP A 22  GLY A 42  1 ? 21 
HELX_P HELX_P8  AA8 ARG B 69  ? SER B 79  ? ARG A 49  SER A 59  1 ? 11 
HELX_P HELX_P9  AA9 ASP B 106 ? PHE B 110 ? ASP A 86  PHE A 90  5 ? 5  
HELX_P HELX_P10 AB1 PRO B 126 ? LEU B 129 ? PRO A 106 LEU A 109 5 ? 4  
HELX_P HELX_P11 AB2 LEU B 134 ? ALA B 150 ? LEU A 114 ALA A 130 1 ? 17 
HELX_P HELX_P12 AB3 LEU B 163 ? LEU B 173 ? LEU A 143 LEU A 153 1 ? 11 
HELX_P HELX_P13 AB4 ASP C 42  ? GLY C 62  ? ASP B 22  GLY B 42  1 ? 21 
HELX_P HELX_P14 AB5 ARG C 69  ? SER C 79  ? ARG B 49  SER B 59  1 ? 11 
HELX_P HELX_P15 AB6 PRO C 126 ? LEU C 129 ? PRO B 106 LEU B 109 5 ? 4  
HELX_P HELX_P16 AB7 LEU C 134 ? ALA C 150 ? LEU B 114 ALA B 130 1 ? 17 
HELX_P HELX_P17 AB8 LEU C 163 ? LEU C 173 ? LEU B 143 LEU B 153 1 ? 11 
HELX_P HELX_P18 AB9 ASP D 42  ? GLY D 62  ? ASP C 22  GLY C 42  1 ? 21 
HELX_P HELX_P19 AC1 ARG D 69  ? SER D 79  ? ARG C 49  SER C 59  1 ? 11 
HELX_P HELX_P20 AC2 PRO D 126 ? LEU D 129 ? PRO C 106 LEU C 109 5 ? 4  
HELX_P HELX_P21 AC3 LEU D 134 ? GLN D 149 ? LEU C 114 GLN C 129 1 ? 16 
HELX_P HELX_P22 AC4 ALA D 150 ? GLY D 152 ? ALA C 130 GLY C 132 5 ? 3  
HELX_P HELX_P23 AC5 LEU D 163 ? LEU D 173 ? LEU C 143 LEU C 153 1 ? 11 
HELX_P HELX_P24 AC6 ASP E 42  ? GLY E 62  ? ASP E 22  GLY E 42  1 ? 21 
HELX_P HELX_P25 AC7 ARG E 69  ? SER E 79  ? ARG E 49  SER E 59  1 ? 11 
HELX_P HELX_P26 AC8 PRO E 126 ? LEU E 129 ? PRO E 106 LEU E 109 5 ? 4  
HELX_P HELX_P27 AC9 VAL E 135 ? ALA E 150 ? VAL E 115 ALA E 130 1 ? 16 
HELX_P HELX_P28 AD1 LEU E 163 ? LEU E 173 ? LEU E 143 LEU E 153 1 ? 11 
HELX_P HELX_P29 AD2 ASP F 42  ? ALA F 59  ? ASP F 22  ALA F 39  1 ? 18 
HELX_P HELX_P30 AD3 ARG F 69  ? SER F 79  ? ARG F 49  SER F 59  1 ? 11 
HELX_P HELX_P31 AD4 PRO F 126 ? LEU F 129 ? PRO F 106 LEU F 109 5 ? 4  
HELX_P HELX_P32 AD5 LEU F 134 ? ALA F 150 ? LEU F 114 ALA F 130 1 ? 17 
HELX_P HELX_P33 AD6 LEU F 163 ? LEU F 173 ? LEU F 143 LEU F 153 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 7 ? 
AA3 ? 7 ? 
AA4 ? 7 ? 
AA5 ? 7 ? 
AA6 ? 7 ? 
AA7 ? 7 ? 
AA8 ? 7 ? 
AA9 ? 7 ? 
AB1 ? 7 ? 
AB2 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? parallel      
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? parallel      
AA2 5 6 ? anti-parallel 
AA2 6 7 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? parallel      
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? parallel      
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? parallel      
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? parallel      
AA6 5 6 ? anti-parallel 
AA6 6 7 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? parallel      
AA7 5 6 ? anti-parallel 
AA7 6 7 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? parallel      
AA8 5 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? parallel      
AA9 5 6 ? anti-parallel 
AA9 6 7 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? parallel      
AB1 5 6 ? anti-parallel 
AB1 6 7 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? parallel      
AB2 5 6 ? anti-parallel 
AB2 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TRP A 35  ? VAL A 39  ? TRP D 15  VAL D 19  
AA1 2 VAL A 82  ? HIS A 87  ? VAL D 62  HIS D 67  
AA1 3 ARG A 90  ? THR A 98  ? ARG D 70  THR D 78  
AA1 4 PRO A 116 ? VAL A 124 ? PRO D 96  VAL D 104 
AA1 5 ALA A 154 ? ALA A 159 ? ALA D 134 ALA D 139 
AA1 6 ARG A 189 ? SER A 196 ? ARG D 169 SER D 176 
AA1 7 VAL A 176 ? GLN A 177 ? VAL D 156 GLN D 157 
AA2 1 TRP A 35  ? VAL A 39  ? TRP D 15  VAL D 19  
AA2 2 VAL A 82  ? HIS A 87  ? VAL D 62  HIS D 67  
AA2 3 ARG A 90  ? THR A 98  ? ARG D 70  THR D 78  
AA2 4 PRO A 116 ? VAL A 124 ? PRO D 96  VAL D 104 
AA2 5 ALA A 154 ? ALA A 159 ? ALA D 134 ALA D 139 
AA2 6 ARG A 189 ? SER A 196 ? ARG D 169 SER D 176 
AA2 7 LEU A 182 ? SER A 183 ? LEU D 162 SER D 163 
AA3 1 TRP B 35  ? VAL B 39  ? TRP A 15  VAL A 19  
AA3 2 VAL B 82  ? HIS B 87  ? VAL A 62  HIS A 67  
AA3 3 ARG B 90  ? THR B 98  ? ARG A 70  THR A 78  
AA3 4 PRO B 116 ? VAL B 124 ? PRO A 96  VAL A 104 
AA3 5 ALA B 154 ? ALA B 159 ? ALA A 134 ALA A 139 
AA3 6 ARG B 189 ? SER B 196 ? ARG A 169 SER A 176 
AA3 7 VAL B 176 ? GLN B 177 ? VAL A 156 GLN A 157 
AA4 1 TRP B 35  ? VAL B 39  ? TRP A 15  VAL A 19  
AA4 2 VAL B 82  ? HIS B 87  ? VAL A 62  HIS A 67  
AA4 3 ARG B 90  ? THR B 98  ? ARG A 70  THR A 78  
AA4 4 PRO B 116 ? VAL B 124 ? PRO A 96  VAL A 104 
AA4 5 ALA B 154 ? ALA B 159 ? ALA A 134 ALA A 139 
AA4 6 ARG B 189 ? SER B 196 ? ARG A 169 SER A 176 
AA4 7 LEU B 182 ? SER B 183 ? LEU A 162 SER A 163 
AA5 1 TRP C 35  ? VAL C 39  ? TRP B 15  VAL B 19  
AA5 2 VAL C 82  ? HIS C 87  ? VAL B 62  HIS B 67  
AA5 3 ARG C 90  ? THR C 98  ? ARG B 70  THR B 78  
AA5 4 PRO C 116 ? VAL C 124 ? PRO B 96  VAL B 104 
AA5 5 ALA C 154 ? ALA C 159 ? ALA B 134 ALA B 139 
AA5 6 ARG C 189 ? SER C 196 ? ARG B 169 SER B 176 
AA5 7 VAL C 176 ? GLN C 177 ? VAL B 156 GLN B 157 
AA6 1 TRP C 35  ? VAL C 39  ? TRP B 15  VAL B 19  
AA6 2 VAL C 82  ? HIS C 87  ? VAL B 62  HIS B 67  
AA6 3 ARG C 90  ? THR C 98  ? ARG B 70  THR B 78  
AA6 4 PRO C 116 ? VAL C 124 ? PRO B 96  VAL B 104 
AA6 5 ALA C 154 ? ALA C 159 ? ALA B 134 ALA B 139 
AA6 6 ARG C 189 ? SER C 196 ? ARG B 169 SER B 176 
AA6 7 LEU C 182 ? SER C 183 ? LEU B 162 SER B 163 
AA7 1 TRP D 35  ? VAL D 39  ? TRP C 15  VAL C 19  
AA7 2 VAL D 82  ? HIS D 87  ? VAL C 62  HIS C 67  
AA7 3 ARG D 90  ? THR D 98  ? ARG C 70  THR C 78  
AA7 4 PRO D 116 ? VAL D 124 ? PRO C 96  VAL C 104 
AA7 5 ALA D 154 ? ALA D 159 ? ALA C 134 ALA C 139 
AA7 6 ARG D 189 ? SER D 196 ? ARG C 169 SER C 176 
AA7 7 VAL D 176 ? GLN D 177 ? VAL C 156 GLN C 157 
AA8 1 TRP D 35  ? VAL D 39  ? TRP C 15  VAL C 19  
AA8 2 VAL D 82  ? HIS D 87  ? VAL C 62  HIS C 67  
AA8 3 ARG D 90  ? THR D 98  ? ARG C 70  THR C 78  
AA8 4 PRO D 116 ? VAL D 124 ? PRO C 96  VAL C 104 
AA8 5 ALA D 154 ? ALA D 159 ? ALA C 134 ALA C 139 
AA8 6 ARG D 189 ? SER D 196 ? ARG C 169 SER C 176 
AA8 7 LEU D 182 ? SER D 183 ? LEU C 162 SER C 163 
AA9 1 TRP E 35  ? VAL E 39  ? TRP E 15  VAL E 19  
AA9 2 VAL E 82  ? HIS E 87  ? VAL E 62  HIS E 67  
AA9 3 ARG E 90  ? THR E 98  ? ARG E 70  THR E 78  
AA9 4 PRO E 116 ? VAL E 124 ? PRO E 96  VAL E 104 
AA9 5 ALA E 154 ? ALA E 159 ? ALA E 134 ALA E 139 
AA9 6 ARG E 189 ? SER E 196 ? ARG E 169 SER E 176 
AA9 7 VAL E 176 ? GLN E 177 ? VAL E 156 GLN E 157 
AB1 1 TRP E 35  ? VAL E 39  ? TRP E 15  VAL E 19  
AB1 2 VAL E 82  ? HIS E 87  ? VAL E 62  HIS E 67  
AB1 3 ARG E 90  ? THR E 98  ? ARG E 70  THR E 78  
AB1 4 PRO E 116 ? VAL E 124 ? PRO E 96  VAL E 104 
AB1 5 ALA E 154 ? ALA E 159 ? ALA E 134 ALA E 139 
AB1 6 ARG E 189 ? SER E 196 ? ARG E 169 SER E 176 
AB1 7 LEU E 182 ? SER E 183 ? LEU E 162 SER E 163 
AB2 1 TRP F 35  ? VAL F 39  ? TRP F 15  VAL F 19  
AB2 2 VAL F 82  ? HIS F 87  ? VAL F 62  HIS F 67  
AB2 3 ARG F 90  ? THR F 98  ? ARG F 70  THR F 78  
AB2 4 PRO F 116 ? VAL F 124 ? PRO F 96  VAL F 104 
AB2 5 ALA F 154 ? ALA F 159 ? ALA F 134 ALA F 139 
AB2 6 VAL F 191 ? SER F 196 ? VAL F 171 SER F 176 
AB2 7 VAL F 176 ? GLN F 177 ? VAL F 156 GLN F 157 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 36  ? N GLN D 16  O ARG A 86  ? O ARG D 66  
AA1 2 3 N LEU A 85  ? N LEU D 65  O ALA A 92  ? O ALA D 72  
AA1 3 4 N THR A 98  ? N THR D 78  O TYR A 118 ? O TYR D 98  
AA1 4 5 N LEU A 119 ? N LEU D 99  O ARG A 156 ? O ARG D 136 
AA1 5 6 N SER A 157 ? N SER D 137 O LEU A 193 ? O LEU D 173 
AA1 6 7 O HIS A 194 ? O HIS D 174 N VAL A 176 ? N VAL D 156 
AA2 1 2 N GLN A 36  ? N GLN D 16  O ARG A 86  ? O ARG D 66  
AA2 2 3 N LEU A 85  ? N LEU D 65  O ALA A 92  ? O ALA D 72  
AA2 3 4 N THR A 98  ? N THR D 78  O TYR A 118 ? O TYR D 98  
AA2 4 5 N LEU A 119 ? N LEU D 99  O ARG A 156 ? O ARG D 136 
AA2 5 6 N SER A 157 ? N SER D 137 O LEU A 193 ? O LEU D 173 
AA2 6 7 O ARG A 190 ? O ARG D 170 N LEU A 182 ? N LEU D 162 
AA3 1 2 N GLN B 36  ? N GLN A 16  O ARG B 86  ? O ARG A 66  
AA3 2 3 N LEU B 85  ? N LEU A 65  O ALA B 92  ? O ALA A 72  
AA3 3 4 N THR B 98  ? N THR A 78  O TYR B 118 ? O TYR A 98  
AA3 4 5 N LEU B 117 ? N LEU A 97  O ALA B 154 ? O ALA A 134 
AA3 5 6 N SER B 157 ? N SER A 137 O LEU B 193 ? O LEU A 173 
AA3 6 7 O HIS B 194 ? O HIS A 174 N VAL B 176 ? N VAL A 156 
AA4 1 2 N GLN B 36  ? N GLN A 16  O ARG B 86  ? O ARG A 66  
AA4 2 3 N LEU B 85  ? N LEU A 65  O ALA B 92  ? O ALA A 72  
AA4 3 4 N THR B 98  ? N THR A 78  O TYR B 118 ? O TYR A 98  
AA4 4 5 N LEU B 117 ? N LEU A 97  O ALA B 154 ? O ALA A 134 
AA4 5 6 N SER B 157 ? N SER A 137 O LEU B 193 ? O LEU A 173 
AA4 6 7 O ARG B 190 ? O ARG A 170 N LEU B 182 ? N LEU A 162 
AA5 1 2 N GLN C 36  ? N GLN B 16  O ARG C 86  ? O ARG B 66  
AA5 2 3 N HIS C 87  ? N HIS B 67  O ARG C 90  ? O ARG B 70  
AA5 3 4 N THR C 98  ? N THR B 78  O TYR C 118 ? O TYR B 98  
AA5 4 5 N LEU C 119 ? N LEU B 99  O ARG C 156 ? O ARG B 136 
AA5 5 6 N LEU C 155 ? N LEU B 135 O LYS C 195 ? O LYS B 175 
AA5 6 7 O HIS C 194 ? O HIS B 174 N VAL C 176 ? N VAL B 156 
AA6 1 2 N GLN C 36  ? N GLN B 16  O ARG C 86  ? O ARG B 66  
AA6 2 3 N HIS C 87  ? N HIS B 67  O ARG C 90  ? O ARG B 70  
AA6 3 4 N THR C 98  ? N THR B 78  O TYR C 118 ? O TYR B 98  
AA6 4 5 N LEU C 119 ? N LEU B 99  O ARG C 156 ? O ARG B 136 
AA6 5 6 N LEU C 155 ? N LEU B 135 O LYS C 195 ? O LYS B 175 
AA6 6 7 O ARG C 190 ? O ARG B 170 N LEU C 182 ? N LEU B 162 
AA7 1 2 N GLU D 38  ? N GLU C 18  O LEU D 84  ? O LEU C 64  
AA7 2 3 N LEU D 85  ? N LEU C 65  O ALA D 92  ? O ALA C 72  
AA7 3 4 N THR D 98  ? N THR C 78  O TYR D 118 ? O TYR C 98  
AA7 4 5 N LEU D 119 ? N LEU C 99  O ARG D 156 ? O ARG C 136 
AA7 5 6 N SER D 157 ? N SER C 137 O LEU D 193 ? O LEU C 173 
AA7 6 7 O HIS D 194 ? O HIS C 174 N VAL D 176 ? N VAL C 156 
AA8 1 2 N GLU D 38  ? N GLU C 18  O LEU D 84  ? O LEU C 64  
AA8 2 3 N LEU D 85  ? N LEU C 65  O ALA D 92  ? O ALA C 72  
AA8 3 4 N THR D 98  ? N THR C 78  O TYR D 118 ? O TYR C 98  
AA8 4 5 N LEU D 119 ? N LEU C 99  O ARG D 156 ? O ARG C 136 
AA8 5 6 N SER D 157 ? N SER C 137 O LEU D 193 ? O LEU C 173 
AA8 6 7 O ARG D 190 ? O ARG C 170 N LEU D 182 ? N LEU C 162 
AA9 1 2 N GLN E 36  ? N GLN E 16  O ARG E 86  ? O ARG E 66  
AA9 2 3 N HIS E 87  ? N HIS E 67  O ARG E 90  ? O ARG E 70  
AA9 3 4 N THR E 98  ? N THR E 78  O TYR E 118 ? O TYR E 98  
AA9 4 5 N LEU E 119 ? N LEU E 99  O ARG E 156 ? O ARG E 136 
AA9 5 6 N SER E 157 ? N SER E 137 O LEU E 193 ? O LEU E 173 
AA9 6 7 O HIS E 194 ? O HIS E 174 N VAL E 176 ? N VAL E 156 
AB1 1 2 N GLN E 36  ? N GLN E 16  O ARG E 86  ? O ARG E 66  
AB1 2 3 N HIS E 87  ? N HIS E 67  O ARG E 90  ? O ARG E 70  
AB1 3 4 N THR E 98  ? N THR E 78  O TYR E 118 ? O TYR E 98  
AB1 4 5 N LEU E 119 ? N LEU E 99  O ARG E 156 ? O ARG E 136 
AB1 5 6 N SER E 157 ? N SER E 137 O LEU E 193 ? O LEU E 173 
AB1 6 7 O ARG E 190 ? O ARG E 170 N LEU E 182 ? N LEU E 162 
AB2 1 2 N GLN F 36  ? N GLN F 16  O ARG F 86  ? O ARG F 66  
AB2 2 3 N HIS F 87  ? N HIS F 67  O ARG F 90  ? O ARG F 70  
AB2 3 4 N THR F 98  ? N THR F 78  O TYR F 118 ? O TYR F 98  
AB2 4 5 N LEU F 117 ? N LEU F 97  O ARG F 156 ? O ARG F 136 
AB2 5 6 N SER F 157 ? N SER F 137 O LEU F 193 ? O LEU F 173 
AB2 6 7 O HIS F 194 ? O HIS F 174 N VAL F 176 ? N VAL F 156 
# 
_pdbx_entry_details.entry_id                   8ZT3 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ALA D 8   ? ? -97.32  -134.83 
2 1 ALA D 84  ? ? -104.82 62.34   
3 1 GLU D 87  ? ? 67.71   -26.59  
4 1 THR D 110 ? B -115.51 -71.17  
5 1 ALA D 130 ? ? -65.73  9.55    
6 1 ALA B 130 ? ? -65.18  8.83    
7 1 LEU E 109 ? ? -90.02  53.30   
# 
_space_group_symop.id              1 
_space_group_symop.operation_xyz   x,y,z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 D MET -19 ? A MET 1   
2   1 Y 1 D GLY -18 ? A GLY 2   
3   1 Y 1 D SER -17 ? A SER 3   
4   1 Y 1 D SER -16 ? A SER 4   
5   1 Y 1 D HIS -15 ? A HIS 5   
6   1 Y 1 D HIS -14 ? A HIS 6   
7   1 Y 1 D HIS -13 ? A HIS 7   
8   1 Y 1 D HIS -12 ? A HIS 8   
9   1 Y 1 D HIS -11 ? A HIS 9   
10  1 Y 1 D HIS -10 ? A HIS 10  
11  1 Y 1 D SER -9  ? A SER 11  
12  1 Y 1 D SER -8  ? A SER 12  
13  1 Y 1 D GLY -7  ? A GLY 13  
14  1 Y 1 D LEU -6  ? A LEU 14  
15  1 Y 1 D VAL -5  ? A VAL 15  
16  1 Y 1 D PRO -4  ? A PRO 16  
17  1 Y 1 D ARG -3  ? A ARG 17  
18  1 Y 1 D GLY -2  ? A GLY 18  
19  1 Y 1 D SER -1  ? A SER 19  
20  1 Y 1 D HIS 0   ? A HIS 20  
21  1 Y 1 D MET 1   ? A MET 21  
22  1 Y 1 D ALA 2   ? A ALA 22  
23  1 Y 1 D ARG 178 ? A ARG 198 
24  1 Y 1 D PRO 179 ? A PRO 199 
25  1 Y 1 D ALA 180 ? A ALA 200 
26  1 Y 1 D SER 181 ? A SER 201 
27  1 Y 1 D PRO 182 ? A PRO 202 
28  1 Y 1 D GLY 183 ? A GLY 203 
29  1 Y 1 D PRO 184 ? A PRO 204 
30  1 Y 1 D GLY 185 ? A GLY 205 
31  1 Y 1 D GLY 186 ? A GLY 206 
32  1 Y 1 D GLU 187 ? A GLU 207 
33  1 Y 1 D ASP 188 ? A ASP 208 
34  1 Y 1 A MET -19 ? B MET 1   
35  1 Y 1 A GLY -18 ? B GLY 2   
36  1 Y 1 A SER -17 ? B SER 3   
37  1 Y 1 A SER -16 ? B SER 4   
38  1 Y 1 A HIS -15 ? B HIS 5   
39  1 Y 1 A HIS -14 ? B HIS 6   
40  1 Y 1 A HIS -13 ? B HIS 7   
41  1 Y 1 A HIS -12 ? B HIS 8   
42  1 Y 1 A HIS -11 ? B HIS 9   
43  1 Y 1 A HIS -10 ? B HIS 10  
44  1 Y 1 A SER -9  ? B SER 11  
45  1 Y 1 A SER -8  ? B SER 12  
46  1 Y 1 A GLY -7  ? B GLY 13  
47  1 Y 1 A LEU -6  ? B LEU 14  
48  1 Y 1 A VAL -5  ? B VAL 15  
49  1 Y 1 A PRO -4  ? B PRO 16  
50  1 Y 1 A ARG -3  ? B ARG 17  
51  1 Y 1 A GLY -2  ? B GLY 18  
52  1 Y 1 A SER -1  ? B SER 19  
53  1 Y 1 A HIS 0   ? B HIS 20  
54  1 Y 1 A MET 1   ? B MET 21  
55  1 Y 1 A ALA 2   ? B ALA 22  
56  1 Y 1 A ASP 3   ? B ASP 23  
57  1 Y 1 A THR 4   ? B THR 24  
58  1 Y 1 A ARG 5   ? B ARG 25  
59  1 Y 1 A ILE 6   ? B ILE 26  
60  1 Y 1 A PRO 7   ? B PRO 27  
61  1 Y 1 A ALA 8   ? B ALA 28  
62  1 Y 1 A GLY 9   ? B GLY 29  
63  1 Y 1 A GLU 10  ? B GLU 30  
64  1 Y 1 A ALA 11  ? B ALA 31  
65  1 Y 1 A THR 12  ? B THR 32  
66  1 Y 1 A ALA 13  ? B ALA 33  
67  1 Y 1 A ARG 178 ? B ARG 198 
68  1 Y 1 A PRO 179 ? B PRO 199 
69  1 Y 1 A ALA 180 ? B ALA 200 
70  1 Y 1 A SER 181 ? B SER 201 
71  1 Y 1 A PRO 182 ? B PRO 202 
72  1 Y 1 A GLY 183 ? B GLY 203 
73  1 Y 1 A PRO 184 ? B PRO 204 
74  1 Y 1 A GLY 185 ? B GLY 205 
75  1 Y 1 A GLY 186 ? B GLY 206 
76  1 Y 1 A GLU 187 ? B GLU 207 
77  1 Y 1 A ASP 188 ? B ASP 208 
78  1 Y 1 B MET -19 ? C MET 1   
79  1 Y 1 B GLY -18 ? C GLY 2   
80  1 Y 1 B SER -17 ? C SER 3   
81  1 Y 1 B SER -16 ? C SER 4   
82  1 Y 1 B HIS -15 ? C HIS 5   
83  1 Y 1 B HIS -14 ? C HIS 6   
84  1 Y 1 B HIS -13 ? C HIS 7   
85  1 Y 1 B HIS -12 ? C HIS 8   
86  1 Y 1 B HIS -11 ? C HIS 9   
87  1 Y 1 B HIS -10 ? C HIS 10  
88  1 Y 1 B SER -9  ? C SER 11  
89  1 Y 1 B SER -8  ? C SER 12  
90  1 Y 1 B GLY -7  ? C GLY 13  
91  1 Y 1 B LEU -6  ? C LEU 14  
92  1 Y 1 B VAL -5  ? C VAL 15  
93  1 Y 1 B PRO -4  ? C PRO 16  
94  1 Y 1 B ARG -3  ? C ARG 17  
95  1 Y 1 B GLY -2  ? C GLY 18  
96  1 Y 1 B SER -1  ? C SER 19  
97  1 Y 1 B HIS 0   ? C HIS 20  
98  1 Y 1 B MET 1   ? C MET 21  
99  1 Y 1 B ALA 2   ? C ALA 22  
100 1 Y 1 B ASP 3   ? C ASP 23  
101 1 Y 1 B THR 4   ? C THR 24  
102 1 Y 1 B ARG 5   ? C ARG 25  
103 1 Y 1 B ILE 6   ? C ILE 26  
104 1 Y 1 B PRO 7   ? C PRO 27  
105 1 Y 1 B ALA 8   ? C ALA 28  
106 1 Y 1 B GLY 9   ? C GLY 29  
107 1 Y 1 B GLU 10  ? C GLU 30  
108 1 Y 1 B ALA 11  ? C ALA 31  
109 1 Y 1 B THR 12  ? C THR 32  
110 1 Y 1 B ALA 13  ? C ALA 33  
111 1 Y 1 B PRO 179 ? C PRO 199 
112 1 Y 1 B ALA 180 ? C ALA 200 
113 1 Y 1 B SER 181 ? C SER 201 
114 1 Y 1 B PRO 182 ? C PRO 202 
115 1 Y 1 B GLY 183 ? C GLY 203 
116 1 Y 1 B PRO 184 ? C PRO 204 
117 1 Y 1 B GLY 185 ? C GLY 205 
118 1 Y 1 B GLY 186 ? C GLY 206 
119 1 Y 1 B GLU 187 ? C GLU 207 
120 1 Y 1 B ASP 188 ? C ASP 208 
121 1 Y 1 C MET -19 ? D MET 1   
122 1 Y 1 C GLY -18 ? D GLY 2   
123 1 Y 1 C SER -17 ? D SER 3   
124 1 Y 1 C SER -16 ? D SER 4   
125 1 Y 1 C HIS -15 ? D HIS 5   
126 1 Y 1 C HIS -14 ? D HIS 6   
127 1 Y 1 C HIS -13 ? D HIS 7   
128 1 Y 1 C HIS -12 ? D HIS 8   
129 1 Y 1 C HIS -11 ? D HIS 9   
130 1 Y 1 C HIS -10 ? D HIS 10  
131 1 Y 1 C SER -9  ? D SER 11  
132 1 Y 1 C SER -8  ? D SER 12  
133 1 Y 1 C GLY -7  ? D GLY 13  
134 1 Y 1 C LEU -6  ? D LEU 14  
135 1 Y 1 C VAL -5  ? D VAL 15  
136 1 Y 1 C PRO -4  ? D PRO 16  
137 1 Y 1 C ARG -3  ? D ARG 17  
138 1 Y 1 C GLY -2  ? D GLY 18  
139 1 Y 1 C SER -1  ? D SER 19  
140 1 Y 1 C HIS 0   ? D HIS 20  
141 1 Y 1 C MET 1   ? D MET 21  
142 1 Y 1 C ALA 2   ? D ALA 22  
143 1 Y 1 C ASP 3   ? D ASP 23  
144 1 Y 1 C THR 4   ? D THR 24  
145 1 Y 1 C ARG 5   ? D ARG 25  
146 1 Y 1 C ILE 6   ? D ILE 26  
147 1 Y 1 C PRO 7   ? D PRO 27  
148 1 Y 1 C ALA 8   ? D ALA 28  
149 1 Y 1 C GLY 9   ? D GLY 29  
150 1 Y 1 C GLU 10  ? D GLU 30  
151 1 Y 1 C ALA 11  ? D ALA 31  
152 1 Y 1 C THR 12  ? D THR 32  
153 1 Y 1 C ALA 13  ? D ALA 33  
154 1 Y 1 C PRO 179 ? D PRO 199 
155 1 Y 1 C ALA 180 ? D ALA 200 
156 1 Y 1 C SER 181 ? D SER 201 
157 1 Y 1 C PRO 182 ? D PRO 202 
158 1 Y 1 C GLY 183 ? D GLY 203 
159 1 Y 1 C PRO 184 ? D PRO 204 
160 1 Y 1 C GLY 185 ? D GLY 205 
161 1 Y 1 C GLY 186 ? D GLY 206 
162 1 Y 1 C GLU 187 ? D GLU 207 
163 1 Y 1 C ASP 188 ? D ASP 208 
164 1 Y 1 E MET -19 ? E MET 1   
165 1 Y 1 E GLY -18 ? E GLY 2   
166 1 Y 1 E SER -17 ? E SER 3   
167 1 Y 1 E SER -16 ? E SER 4   
168 1 Y 1 E HIS -15 ? E HIS 5   
169 1 Y 1 E HIS -14 ? E HIS 6   
170 1 Y 1 E HIS -13 ? E HIS 7   
171 1 Y 1 E HIS -12 ? E HIS 8   
172 1 Y 1 E HIS -11 ? E HIS 9   
173 1 Y 1 E HIS -10 ? E HIS 10  
174 1 Y 1 E SER -9  ? E SER 11  
175 1 Y 1 E SER -8  ? E SER 12  
176 1 Y 1 E GLY -7  ? E GLY 13  
177 1 Y 1 E LEU -6  ? E LEU 14  
178 1 Y 1 E VAL -5  ? E VAL 15  
179 1 Y 1 E PRO -4  ? E PRO 16  
180 1 Y 1 E ARG -3  ? E ARG 17  
181 1 Y 1 E GLY -2  ? E GLY 18  
182 1 Y 1 E SER -1  ? E SER 19  
183 1 Y 1 E HIS 0   ? E HIS 20  
184 1 Y 1 E MET 1   ? E MET 21  
185 1 Y 1 E ALA 2   ? E ALA 22  
186 1 Y 1 E ASP 3   ? E ASP 23  
187 1 Y 1 E THR 4   ? E THR 24  
188 1 Y 1 E ARG 5   ? E ARG 25  
189 1 Y 1 E ILE 6   ? E ILE 26  
190 1 Y 1 E PRO 7   ? E PRO 27  
191 1 Y 1 E ALA 8   ? E ALA 28  
192 1 Y 1 E GLY 9   ? E GLY 29  
193 1 Y 1 E GLU 10  ? E GLU 30  
194 1 Y 1 E ALA 11  ? E ALA 31  
195 1 Y 1 E THR 12  ? E THR 32  
196 1 Y 1 E ALA 13  ? E ALA 33  
197 1 Y 1 E ASP 86  ? E ASP 106 
198 1 Y 1 E GLU 87  ? E GLU 107 
199 1 Y 1 E GLY 88  ? E GLY 108 
200 1 Y 1 E ALA 89  ? E ALA 109 
201 1 Y 1 E GLY 111 ? E GLY 131 
202 1 Y 1 E GLY 112 ? E GLY 132 
203 1 Y 1 E SER 113 ? E SER 133 
204 1 Y 1 E PRO 184 ? E PRO 204 
205 1 Y 1 E GLY 185 ? E GLY 205 
206 1 Y 1 E GLY 186 ? E GLY 206 
207 1 Y 1 F MET -19 ? F MET 1   
208 1 Y 1 F GLY -18 ? F GLY 2   
209 1 Y 1 F SER -17 ? F SER 3   
210 1 Y 1 F SER -16 ? F SER 4   
211 1 Y 1 F HIS -15 ? F HIS 5   
212 1 Y 1 F HIS -14 ? F HIS 6   
213 1 Y 1 F HIS -13 ? F HIS 7   
214 1 Y 1 F HIS -12 ? F HIS 8   
215 1 Y 1 F HIS -11 ? F HIS 9   
216 1 Y 1 F HIS -10 ? F HIS 10  
217 1 Y 1 F SER -9  ? F SER 11  
218 1 Y 1 F SER -8  ? F SER 12  
219 1 Y 1 F GLY -7  ? F GLY 13  
220 1 Y 1 F LEU -6  ? F LEU 14  
221 1 Y 1 F VAL -5  ? F VAL 15  
222 1 Y 1 F PRO -4  ? F PRO 16  
223 1 Y 1 F ARG -3  ? F ARG 17  
224 1 Y 1 F GLY -2  ? F GLY 18  
225 1 Y 1 F SER -1  ? F SER 19  
226 1 Y 1 F HIS 0   ? F HIS 20  
227 1 Y 1 F MET 1   ? F MET 21  
228 1 Y 1 F ALA 2   ? F ALA 22  
229 1 Y 1 F ASP 3   ? F ASP 23  
230 1 Y 1 F THR 4   ? F THR 24  
231 1 Y 1 F ARG 5   ? F ARG 25  
232 1 Y 1 F ILE 6   ? F ILE 26  
233 1 Y 1 F PRO 7   ? F PRO 27  
234 1 Y 1 F ALA 8   ? F ALA 28  
235 1 Y 1 F GLY 9   ? F GLY 29  
236 1 Y 1 F GLU 10  ? F GLU 30  
237 1 Y 1 F ALA 11  ? F ALA 31  
238 1 Y 1 F THR 12  ? F THR 32  
239 1 Y 1 F ALA 13  ? F ALA 33  
240 1 Y 1 F ALA 40  ? F ALA 60  
241 1 Y 1 F SER 41  ? F SER 61  
242 1 Y 1 F GLY 42  ? F GLY 62  
243 1 Y 1 F THR 43  ? F THR 63  
244 1 Y 1 F GLY 111 ? F GLY 131 
245 1 Y 1 F GLY 112 ? F GLY 132 
246 1 Y 1 F ASP 164 ? F ASP 184 
247 1 Y 1 F GLY 165 ? F GLY 185 
248 1 Y 1 F GLN 166 ? F GLN 186 
249 1 Y 1 F GLY 167 ? F GLY 187 
250 1 Y 1 F ARG 168 ? F ARG 188 
251 1 Y 1 F ALA 180 ? F ALA 200 
252 1 Y 1 F SER 181 ? F SER 201 
253 1 Y 1 F PRO 182 ? F PRO 202 
254 1 Y 1 F GLY 183 ? F GLY 203 
255 1 Y 1 F PRO 184 ? F PRO 204 
256 1 Y 1 F GLY 185 ? F GLY 205 
257 1 Y 1 F GLY 186 ? F GLY 206 
258 1 Y 1 F GLU 187 ? F GLU 207 
259 1 Y 1 F ASP 188 ? F ASP 208 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
THR N    N  N N 305 
THR CA   C  N S 306 
THR C    C  N N 307 
THR O    O  N N 308 
THR CB   C  N R 309 
THR OG1  O  N N 310 
THR CG2  C  N N 311 
THR OXT  O  N N 312 
THR H    H  N N 313 
THR H2   H  N N 314 
THR HA   H  N N 315 
THR HB   H  N N 316 
THR HG1  H  N N 317 
THR HG21 H  N N 318 
THR HG22 H  N N 319 
THR HG23 H  N N 320 
THR HXT  H  N N 321 
TRP N    N  N N 322 
TRP CA   C  N S 323 
TRP C    C  N N 324 
TRP O    O  N N 325 
TRP CB   C  N N 326 
TRP CG   C  Y N 327 
TRP CD1  C  Y N 328 
TRP CD2  C  Y N 329 
TRP NE1  N  Y N 330 
TRP CE2  C  Y N 331 
TRP CE3  C  Y N 332 
TRP CZ2  C  Y N 333 
TRP CZ3  C  Y N 334 
TRP CH2  C  Y N 335 
TRP OXT  O  N N 336 
TRP H    H  N N 337 
TRP H2   H  N N 338 
TRP HA   H  N N 339 
TRP HB2  H  N N 340 
TRP HB3  H  N N 341 
TRP HD1  H  N N 342 
TRP HE1  H  N N 343 
TRP HE3  H  N N 344 
TRP HZ2  H  N N 345 
TRP HZ3  H  N N 346 
TRP HH2  H  N N 347 
TRP HXT  H  N N 348 
TYR N    N  N N 349 
TYR CA   C  N S 350 
TYR C    C  N N 351 
TYR O    O  N N 352 
TYR CB   C  N N 353 
TYR CG   C  Y N 354 
TYR CD1  C  Y N 355 
TYR CD2  C  Y N 356 
TYR CE1  C  Y N 357 
TYR CE2  C  Y N 358 
TYR CZ   C  Y N 359 
TYR OH   O  N N 360 
TYR OXT  O  N N 361 
TYR H    H  N N 362 
TYR H2   H  N N 363 
TYR HA   H  N N 364 
TYR HB2  H  N N 365 
TYR HB3  H  N N 366 
TYR HD1  H  N N 367 
TYR HD2  H  N N 368 
TYR HE1  H  N N 369 
TYR HE2  H  N N 370 
TYR HH   H  N N 371 
TYR HXT  H  N N 372 
VAL N    N  N N 373 
VAL CA   C  N S 374 
VAL C    C  N N 375 
VAL O    O  N N 376 
VAL CB   C  N N 377 
VAL CG1  C  N N 378 
VAL CG2  C  N N 379 
VAL OXT  O  N N 380 
VAL H    H  N N 381 
VAL H2   H  N N 382 
VAL HA   H  N N 383 
VAL HB   H  N N 384 
VAL HG11 H  N N 385 
VAL HG12 H  N N 386 
VAL HG13 H  N N 387 
VAL HG21 H  N N 388 
VAL HG22 H  N N 389 
VAL HG23 H  N N 390 
VAL HXT  H  N N 391 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1' 
_space_group.name_Hall        'P 1' 
_space_group.IT_number        1 
_space_group.crystal_system   triclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8ZT3 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.019701 
_atom_sites.fract_transf_matrix[1][2]   0.000002 
_atom_sites.fract_transf_matrix[1][3]   0.000292 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015529 
_atom_sites.fract_transf_matrix[2][3]   0.005209 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011328 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? ?       ?       ? ? ?        ?        ? ? ?   ? ? 
N  ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ASP A 1 23  ? 19.64712  -42.58004 68.32554  1.000 68.86116  ? 3   ASP D N   1 
ATOM   2    C  CA  . ASP A 1 23  ? 20.88326  -42.02926 67.78028  1.000 78.87007  ? 3   ASP D CA  1 
ATOM   3    C  C   . ASP A 1 23  ? 20.68582  -41.60778 66.32800  1.000 78.99051  ? 3   ASP D C   1 
ATOM   4    O  O   . ASP A 1 23  ? 21.09940  -42.30993 65.40803  1.000 76.09041  ? 3   ASP D O   1 
ATOM   5    C  CB  . ASP A 1 23  ? 22.02046  -43.04926 67.88801  1.000 62.79579  ? 3   ASP D CB  1 
ATOM   6    C  CG  . ASP A 1 23  ? 23.37455  -42.46072 67.52547  1.000 66.18075  ? 3   ASP D CG  1 
ATOM   7    O  OD1 . ASP A 1 23  ? 23.46469  -41.23127 67.32157  1.000 64.45613  ? 3   ASP D OD1 1 
ATOM   8    O  OD2 . ASP A 1 23  ? 24.35337  -43.23239 67.44510  1.000 71.86326  ? 3   ASP D OD2 1 
ATOM   9    N  N   . THR A 1 24  ? 20.05952  -40.45227 66.13087  1.000 77.07648  ? 4   THR D N   1 
ATOM   10   C  CA  . THR A 1 24  ? 19.74677  -39.95977 64.79775  1.000 72.51593  ? 4   THR D CA  1 
ATOM   11   C  C   . THR A 1 24  ? 20.90513  -39.13430 64.24806  1.000 80.50991  ? 4   THR D C   1 
ATOM   12   O  O   . THR A 1 24  ? 21.50514  -38.32679 64.96443  1.000 80.36423  ? 4   THR D O   1 
ATOM   13   C  CB  . THR A 1 24  ? 18.46894  -39.12057 64.82837  1.000 67.17094  ? 4   THR D CB  1 
ATOM   14   O  OG1 . THR A 1 24  ? 17.48236  -39.78407 65.62909  1.000 78.76958  ? 4   THR D OG1 1 
ATOM   15   C  CG2 . THR A 1 24  ? 17.92309  -38.94263 63.42951  1.000 65.74294  ? 4   THR D CG2 1 
ATOM   16   N  N   . ARG A 1 25  ? 21.21635  -39.34468 62.96889  1.000 78.71773  ? 5   ARG D N   1 
ATOM   17   C  CA  . ARG A 1 25  ? 22.32134  -38.66613 62.29079  1.000 74.90087  ? 5   ARG D CA  1 
ATOM   18   C  C   . ARG A 1 25  ? 21.77752  -37.96621 61.04707  1.000 73.32356  ? 5   ARG D C   1 
ATOM   19   O  O   . ARG A 1 25  ? 21.62621  -38.59332 59.99430  1.000 72.05779  ? 5   ARG D O   1 
ATOM   20   C  CB  . ARG A 1 25  ? 23.42793  -39.65578 61.92397  1.000 73.19599  ? 5   ARG D CB  1 
ATOM   21   C  CG  . ARG A 1 25  ? 23.90254  -40.53408 63.07045  1.000 72.82409  ? 5   ARG D CG  1 
ATOM   22   C  CD  . ARG A 1 25  ? 24.65567  -39.73910 64.12151  1.000 75.78636  ? 5   ARG D CD  1 
ATOM   23   N  NE  . ARG A 1 25  ? 25.12196  -40.59402 65.20664  1.000 70.71911  ? 5   ARG D NE  1 
ATOM   24   C  CZ  . ARG A 1 25  ? 26.31075  -41.18079 65.24092  1.000 77.05735  ? 5   ARG D CZ  1 
ATOM   25   N  NH1 . ARG A 1 25  ? 27.19410  -41.01113 64.27058  1.000 67.63477  ? 5   ARG D NH1 1 
ATOM   26   N  NH2 . ARG A 1 25  ? 26.62154  -41.95695 66.27527  1.000 75.12379  ? 5   ARG D NH2 1 
ATOM   27   N  N   . ILE A 1 26  ? 21.48574  -36.67685 61.16556  1.000 74.78087  ? 6   ILE D N   1 
ATOM   28   C  CA  . ILE A 1 26  ? 21.07651  -35.88003 60.00614  1.000 75.21409  ? 6   ILE D CA  1 
ATOM   29   C  C   . ILE A 1 26  ? 22.32818  -35.42275 59.26134  1.000 82.07862  ? 6   ILE D C   1 
ATOM   30   O  O   . ILE A 1 26  ? 23.23881  -34.85458 59.88700  1.000 75.72911  ? 6   ILE D O   1 
ATOM   31   C  CB  . ILE A 1 26  ? 20.22451  -34.68714 60.43864  1.000 75.69447  ? 6   ILE D CB  1 
ATOM   32   C  CG1 . ILE A 1 26  ? 18.77295  -35.11388 60.68528  1.000 78.80294  ? 6   ILE D CG1 1 
ATOM   33   C  CG2 . ILE A 1 26  ? 20.24847  -33.59167 59.38223  1.000 65.45654  ? 6   ILE D CG2 1 
ATOM   34   C  CD1 . ILE A 1 26  ? 18.50859  -35.69506 62.05870  1.000 73.66251  ? 6   ILE D CD1 1 
ATOM   35   N  N   . PRO A 1 27  ? 22.41727  -35.65379 57.95039  1.000 81.07199  ? 7   PRO D N   1 
ATOM   36   C  CA  . PRO A 1 27  ? 23.62154  -35.26173 57.20213  1.000 75.53261  ? 7   PRO D CA  1 
ATOM   37   C  C   . PRO A 1 27  ? 23.71492  -33.74833 57.07777  1.000 76.87673  ? 7   PRO D C   1 
ATOM   38   O  O   . PRO A 1 27  ? 22.80341  -33.09251 56.57281  1.000 77.17507  ? 7   PRO D O   1 
ATOM   39   C  CB  . PRO A 1 27  ? 23.42547  -35.93220 55.83749  1.000 74.44156  ? 7   PRO D CB  1 
ATOM   40   C  CG  . PRO A 1 27  ? 21.95075  -36.07069 55.70264  1.000 70.90676  ? 7   PRO D CG  1 
ATOM   41   C  CD  . PRO A 1 27  ? 21.42493  -36.32167 57.09045  1.000 79.87824  ? 7   PRO D CD  1 
ATOM   42   N  N   . ALA A 1 28  ? 24.82321  -33.19436 57.55513  1.000 79.93966  ? 8   ALA D N   1 
ATOM   43   C  CA  . ALA A 1 28  ? 25.08923  -31.76795 57.41422  1.000 76.38136  ? 8   ALA D CA  1 
ATOM   44   C  C   . ALA A 1 28  ? 25.99764  -31.53263 56.21380  1.000 72.35621  ? 8   ALA D C   1 
ATOM   45   O  O   . ALA A 1 28  ? 25.77334  -32.11635 55.14549  1.000 83.81911  ? 8   ALA D O   1 
ATOM   46   C  CB  . ALA A 1 28  ? 25.69609  -31.20764 58.70230  1.000 75.96198  ? 8   ALA D CB  1 
ATOM   47   N  N   . GLY A 1 29  ? 27.02065  -30.69508 56.37170  1.000 63.11923  ? 9   GLY D N   1 
ATOM   48   C  CA  . GLY A 1 29  ? 27.94377  -30.41931 55.28666  1.000 53.10097  ? 9   GLY D CA  1 
ATOM   49   C  C   . GLY A 1 29  ? 27.45631  -29.31208 54.36122  1.000 45.63543  ? 9   GLY D C   1 
ATOM   50   O  O   . GLY A 1 29  ? 26.26514  -29.02771 54.25200  1.000 48.27173  ? 9   GLY D O   1 
ATOM   51   N  N   . GLU A 1 30  ? 28.41327  -28.67228 53.67644  1.000 38.41568  ? 10  GLU D N   1 
ATOM   52   C  CA  . GLU A 1 30  ? 28.07169  -27.56571 52.78440  1.000 44.90888  ? 10  GLU D CA  1 
ATOM   53   C  C   . GLU A 1 30  ? 27.34644  -28.04514 51.53048  1.000 47.91498  ? 10  GLU D C   1 
ATOM   54   O  O   . GLU A 1 30  ? 26.52095  -27.30709 50.97879  1.000 43.28093  ? 10  GLU D O   1 
ATOM   55   C  CB  . GLU A 1 30  ? 29.33534  -26.78242 52.42403  1.000 36.30213  ? 10  GLU D CB  1 
ATOM   56   C  CG  . GLU A 1 30  ? 30.03601  -26.19625 53.63981  1.000 33.30615  ? 10  GLU D CG  1 
ATOM   57   C  CD  . GLU A 1 30  ? 31.17494  -25.27025 53.27860  1.000 37.68787  ? 10  GLU D CD  1 
ATOM   58   O  OE1 . GLU A 1 30  ? 31.69123  -25.38868 52.15058  1.000 41.63015  ? 10  GLU D OE1 1 
ATOM   59   O  OE2 . GLU A 1 30  ? 31.54723  -24.42092 54.11853  1.000 30.54922  ? 10  GLU D OE2 1 
ATOM   60   N  N   . ALA A 1 31  ? 27.63271  -29.26840 51.07169  1.000 47.39481  ? 11  ALA D N   1 
ATOM   61   C  CA  . ALA A 1 31  ? 26.96173  -29.79948 49.88859  1.000 49.11468  ? 11  ALA D CA  1 
ATOM   62   C  C   . ALA A 1 31  ? 25.46085  -29.94111 50.11700  1.000 52.32872  ? 11  ALA D C   1 
ATOM   63   O  O   . ALA A 1 31  ? 24.65720  -29.60558 49.23844  1.000 49.81666  ? 11  ALA D O   1 
ATOM   64   C  CB  . ALA A 1 31  ? 27.58047  -31.14089 49.50218  1.000 42.17743  ? 11  ALA D CB  1 
ATOM   65   N  N   . THR A 1 32  ? 25.06339  -30.44281 51.28905  1.000 46.85824  ? 12  THR D N   1 
ATOM   66   C  CA  . THR A 1 32  ? 23.64450  -30.49885 51.62936  1.000 49.19007  ? 12  THR D CA  1 
ATOM   67   C  C   . THR A 1 32  ? 23.05833  -29.09770 51.76554  1.000 43.56194  ? 12  THR D C   1 
ATOM   68   O  O   . THR A 1 32  ? 21.98186  -28.80826 51.23027  1.000 41.18530  ? 12  THR D O   1 
ATOM   69   C  CB  . THR A 1 32  ? 23.44417  -31.29433 52.92174  1.000 61.21592  ? 12  THR D CB  1 
ATOM   70   O  OG1 . THR A 1 32  ? 23.65738  -32.68884 52.66815  1.000 69.50151  ? 12  THR D OG1 1 
ATOM   71   C  CG2 . THR A 1 32  ? 22.04219  -31.08658 53.47536  1.000 49.77155  ? 12  THR D CG2 1 
ATOM   72   N  N   . ALA A 1 33  ? 23.76275  -28.20744 52.46776  1.000 42.83527  ? 13  ALA D N   1 
ATOM   73   C  CA  . ALA A 1 33  ? 23.26230  -26.85896 52.70538  1.000 45.47087  ? 13  ALA D CA  1 
ATOM   74   C  C   . ALA A 1 33  ? 23.17583  -26.02440 51.43736  1.000 41.61266  ? 13  ALA D C   1 
ATOM   75   O  O   . ALA A 1 33  ? 22.57177  -24.94628 51.46986  1.000 39.88174  ? 13  ALA D O   1 
ATOM   76   C  CB  . ALA A 1 33  ? 24.14408  -26.14173 53.72631  1.000 36.48888  ? 13  ALA D CB  1 
ATOM   77   N  N   . ALA A 1 34  ? 23.77194  -26.48206 50.33402  1.000 44.43453  ? 14  ALA D N   1 
ATOM   78   C  CA  . ALA A 1 34  ? 23.65031  -25.75438 49.07606  1.000 45.32932  ? 14  ALA D CA  1 
ATOM   79   C  C   . ALA A 1 34  ? 22.21244  -25.70537 48.56564  1.000 44.86016  ? 14  ALA D C   1 
ATOM   80   O  O   . ALA A 1 34  ? 21.88492  -24.82930 47.75741  1.000 36.24306  ? 14  ALA D O   1 
ATOM   81   C  CB  . ALA A 1 34  ? 24.56427  -26.38251 48.02059  1.000 33.41309  ? 14  ALA D CB  1 
ATOM   82   N  N   . TRP A 1 35  ? 21.35030  -26.61425 49.02021  1.000 38.41453  ? 15  TRP D N   1 
ATOM   83   C  CA  . TRP A 1 35  ? 19.94876  -26.65486 48.61536  1.000 42.65740  ? 15  TRP D CA  1 
ATOM   84   C  C   . TRP A 1 35  ? 19.08903  -26.01599 49.70033  1.000 41.88636  ? 15  TRP D C   1 
ATOM   85   O  O   . TRP A 1 35  ? 19.13278  -26.44078 50.86064  1.000 42.56444  ? 15  TRP D O   1 
ATOM   86   C  CB  . TRP A 1 35  ? 19.49822  -28.09282 48.35637  1.000 35.72842  ? 15  TRP D CB  1 
ATOM   87   C  CG  . TRP A 1 35  ? 20.24716  -28.76674 47.24874  1.000 42.24816  ? 15  TRP D CG  1 
ATOM   88   C  CD1 . TRP A 1 35  ? 21.39591  -29.49811 47.35960  1.000 39.13871  ? 15  TRP D CD1 1 
ATOM   89   C  CD2 . TRP A 1 35  ? 19.90392  -28.76802 45.85643  1.000 42.98778  ? 15  TRP D CD2 1 
ATOM   90   N  NE1 . TRP A 1 35  ? 21.78719  -29.95485 46.12277  1.000 42.05758  ? 15  TRP D NE1 1 
ATOM   91   C  CE2 . TRP A 1 35  ? 20.88853  -29.52096 45.18361  1.000 44.16964  ? 15  TRP D CE2 1 
ATOM   92   C  CE3 . TRP A 1 35  ? 18.85970  -28.20665 45.11403  1.000 32.98904  ? 15  TRP D CE3 1 
ATOM   93   C  CZ2 . TRP A 1 35  ? 20.85890  -29.72644 43.80414  1.000 42.29270  ? 15  TRP D CZ2 1 
ATOM   94   C  CZ3 . TRP A 1 35  ? 18.83247  -28.41115 43.74566  1.000 35.65177  ? 15  TRP D CZ3 1 
ATOM   95   C  CH2 . TRP A 1 35  ? 19.82561  -29.16397 43.10513  1.000 45.38100  ? 15  TRP D CH2 1 
ATOM   96   N  N   . GLN A 1 36  ? 18.31280  -24.99817 49.32626  1.000 35.12185  ? 16  GLN D N   1 
ATOM   97   C  CA  . GLN A 1 36  ? 17.49650  -24.26297 50.28791  1.000 38.60237  ? 16  GLN D CA  1 
ATOM   98   C  C   . GLN A 1 36  ? 16.09123  -24.04481 49.74091  1.000 41.18135  ? 16  GLN D C   1 
ATOM   99   O  O   . GLN A 1 36  ? 15.92577  -23.55990 48.61744  1.000 36.50177  ? 16  GLN D O   1 
ATOM   100  C  CB  . GLN A 1 36  ? 18.13790  -22.90976 50.63280  1.000 46.07660  ? 16  GLN D CB  1 
ATOM   101  C  CG  . GLN A 1 36  ? 19.48120  -23.00676 51.35392  1.000 44.70304  ? 16  GLN D CG  1 
ATOM   102  C  CD  . GLN A 1 36  ? 19.35781  -23.53644 52.77215  1.000 49.68918  ? 16  GLN D CD  1 
ATOM   103  O  OE1 . GLN A 1 36  ? 18.28697  -23.48022 53.37810  1.000 54.91197  ? 16  GLN D OE1 1 
ATOM   104  N  NE2 . GLN A 1 36  ? 20.45815  -24.05528 53.30832  1.000 44.99684  ? 16  GLN D NE2 1 
ATOM   105  N  N   . TRP A 1 37  ? 15.08293  -24.38794 50.53807  1.000 33.14539  ? 17  TRP D N   1 
ATOM   106  C  CA  . TRP A 1 37  ? 13.69312  -24.12506 50.19281  1.000 34.45494  ? 17  TRP D CA  1 
ATOM   107  C  C   . TRP A 1 37  ? 13.24581  -22.79358 50.78471  1.000 36.28610  ? 17  TRP D C   1 
ATOM   108  O  O   . TRP A 1 37  ? 13.71293  -22.37819 51.84880  1.000 37.31774  ? 17  TRP D O   1 
ATOM   109  C  CB  . TRP A 1 37  ? 12.77346  -25.24276 50.69086  1.000 32.94228  ? 17  TRP D CB  1 
ATOM   110  C  CG  . TRP A 1 37  ? 12.70698  -26.42767 49.77915  1.000 31.54076  ? 17  TRP D CG  1 
ATOM   111  C  CD1 . TRP A 1 37  ? 13.33156  -27.62689 49.95004  1.000 26.74828  ? 17  TRP D CD1 1 
ATOM   112  C  CD2 . TRP A 1 37  ? 11.97586  -26.52627 48.54967  1.000 31.91077  ? 17  TRP D CD2 1 
ATOM   113  N  NE1 . TRP A 1 37  ? 13.03618  -28.46837 48.90438  1.000 40.23282  ? 17  TRP D NE1 1 
ATOM   114  C  CE2 . TRP A 1 37  ? 12.20580  -27.81647 48.03075  1.000 32.70533  ? 17  TRP D CE2 1 
ATOM   115  C  CE3 . TRP A 1 37  ? 11.14977  -25.64978 47.83786  1.000 30.17773  ? 17  TRP D CE3 1 
ATOM   116  C  CZ2 . TRP A 1 37  ? 11.63927  -28.25261 46.83264  1.000 34.16698  ? 17  TRP D CZ2 1 
ATOM   117  C  CZ3 . TRP A 1 37  ? 10.58881  -26.08439 46.64815  1.000 31.30543  ? 17  TRP D CZ3 1 
ATOM   118  C  CH2 . TRP A 1 37  ? 10.83507  -27.37372 46.15785  1.000 28.16285  ? 17  TRP D CH2 1 
ATOM   119  N  N   . GLU A 1 38  ? 12.32847  -22.12787 50.08374  1.000 37.67552  ? 18  GLU D N   1 
ATOM   120  C  CA  . GLU A 1 38  ? 11.79063  -20.86007 50.55175  1.000 30.64076  ? 18  GLU D CA  1 
ATOM   121  C  C   . GLU A 1 38  ? 10.38056  -20.68357 50.01189  1.000 41.66884  ? 18  GLU D C   1 
ATOM   122  O  O   . GLU A 1 38  ? 9.98633   -21.31188 49.02550  1.000 40.52679  ? 18  GLU D O   1 
ATOM   123  C  CB  . GLU A 1 38  ? 12.67018  -19.67816 50.12057  1.000 33.70616  ? 18  GLU D CB  1 
ATOM   124  C  CG  . GLU A 1 38  ? 12.56074  -19.34027 48.63891  1.000 36.17593  ? 18  GLU D CG  1 
ATOM   125  C  CD  . GLU A 1 38  ? 13.55686  -18.28635 48.19430  1.000 39.35326  ? 18  GLU D CD  1 
ATOM   126  O  OE1 . GLU A 1 38  ? 14.74561  -18.38590 48.56697  1.000 40.79394  ? 18  GLU D OE1 1 
ATOM   127  O  OE2 . GLU A 1 38  ? 13.14964  -17.35420 47.47010  1.000 40.10708  ? 18  GLU D OE2 1 
ATOM   128  N  N   . VAL A 1 39  ? 9.62050   -19.82506 50.68406  1.000 44.93265  ? 19  VAL D N   1 
ATOM   129  C  CA  . VAL A 1 39  ? 8.38027   -19.28939 50.13645  1.000 38.66582  ? 19  VAL D CA  1 
ATOM   130  C  C   . VAL A 1 39  ? 8.74088   -18.05324 49.32706  1.000 34.99141  ? 19  VAL D C   1 
ATOM   131  O  O   . VAL A 1 39  ? 9.25160   -17.07151 49.87481  1.000 42.80753  ? 19  VAL D O   1 
ATOM   132  C  CB  . VAL A 1 39  ? 7.37151   -18.95712 51.24527  1.000 37.06895  ? 19  VAL D CB  1 
ATOM   133  C  CG1 . VAL A 1 39  ? 6.12618   -18.29702 50.65603  1.000 25.89606  ? 19  VAL D CG1 1 
ATOM   134  C  CG2 . VAL A 1 39  ? 7.00102   -20.21817 52.00967  1.000 38.49055  ? 19  VAL D CG2 1 
ATOM   135  N  N   . SER A 1 40  ? 8.48421   -18.10350 48.02545  1.000 37.16337  ? 20  SER D N   1 
ATOM   136  C  CA  . SER A 1 40  ? 8.99459   -17.08123 47.12587  1.000 31.96732  ? 20  SER D CA  1 
ATOM   137  C  C   . SER A 1 40  ? 8.31257   -15.73972 47.35426  1.000 36.73671  ? 20  SER D C   1 
ATOM   138  O  O   . SER A 1 40  ? 7.11753   -15.66959 47.65296  1.000 42.93564  ? 20  SER D O   1 
ATOM   139  C  CB  . SER A 1 40  ? 8.80201   -17.50957 45.67532  1.000 36.15960  ? 20  SER D CB  1 
ATOM   140  O  OG  . SER A 1 40  ? 9.27316   -16.49742 44.80690  1.000 34.79901  ? 20  SER D OG  1 
ATOM   141  N  N   . ARG A 1 41  ? 9.08901   -14.66587 47.19938  1.000 44.33175  ? 21  ARG D N   1 
ATOM   142  C  CA  . ARG A 1 41  ? 8.55794   -13.31076 47.22485  1.000 46.40828  ? 21  ARG D CA  1 
ATOM   143  C  C   . ARG A 1 41  ? 9.01120   -12.48694 46.02498  1.000 47.84349  ? 21  ARG D C   1 
ATOM   144  O  O   . ARG A 1 41  ? 8.77063   -11.27404 45.99590  1.000 53.34963  ? 21  ARG D O   1 
ATOM   145  C  CB  . ARG A 1 41  ? 8.94935   -12.59377 48.52274  1.000 39.77386  ? 21  ARG D CB  1 
ATOM   146  C  CG  . ARG A 1 41  ? 8.00027   -12.82136 49.69152  1.000 61.11535  ? 21  ARG D CG  1 
ATOM   147  C  CD  . ARG A 1 41  ? 6.57342   -12.35733 49.38337  1.000 70.65321  ? 21  ARG D CD  1 
ATOM   148  N  NE  . ARG A 1 41  ? 6.52535   -11.24219 48.44329  1.000 73.10595  ? 21  ARG D NE  1 
ATOM   149  C  CZ  . ARG A 1 41  ? 5.43571   -10.53916 48.16519  1.000 75.63772  ? 21  ARG D CZ  1 
ATOM   150  N  NH1 . ARG A 1 41  ? 4.29305   -10.75586 48.79637  1.000 73.76105  ? 21  ARG D NH1 1 
ATOM   151  N  NH2 . ARG A 1 41  ? 5.49416   -9.59447  47.23022  1.000 72.89172  ? 21  ARG D NH2 1 
ATOM   152  N  N   . ASP A 1 42  ? 9.65112   -13.10775 45.03720  1.000 38.19121  ? 22  ASP D N   1 
ATOM   153  C  CA  . ASP A 1 42  ? 10.16860  -12.41725 43.86039  1.000 42.49244  ? 22  ASP D CA  1 
ATOM   154  C  C   . ASP A 1 42  ? 9.34706   -12.86157 42.65598  1.000 42.56135  ? 22  ASP D C   1 
ATOM   155  O  O   . ASP A 1 42  ? 9.47648   -13.99999 42.19350  1.000 48.76672  ? 22  ASP D O   1 
ATOM   156  C  CB  . ASP A 1 42  ? 11.65438  -12.71740 43.66552  1.000 43.75534  ? 22  ASP D CB  1 
ATOM   157  C  CG  . ASP A 1 42  ? 12.33593  -11.73823 42.72678  1.000 51.29978  ? 22  ASP D CG  1 
ATOM   158  O  OD1 . ASP A 1 42  ? 11.65762  -11.17958 41.83859  1.000 58.43903  ? 22  ASP D OD1 1 
ATOM   159  O  OD2 . ASP A 1 42  ? 13.55746  -11.52882 42.87932  1.000 59.27276  ? 22  ASP D OD2 1 
ATOM   160  N  N   . THR A 1 43  ? 8.51209   -11.95734 42.14382  1.000 40.05574  ? 23  THR D N   1 
ATOM   161  C  CA  . THR A 1 43  ? 7.61147   -12.31026 41.05061  1.000 36.17624  ? 23  THR D CA  1 
ATOM   162  C  C   . THR A 1 43  ? 8.37115   -12.52452 39.74536  1.000 33.68322  ? 23  THR D C   1 
ATOM   163  O  O   . THR A 1 43  ? 8.12391   -13.49971 39.02327  1.000 34.13247  ? 23  THR D O   1 
ATOM   164  C  CB  . THR A 1 43  ? 6.54791   -11.22374 40.88494  1.000 35.52136  ? 23  THR D CB  1 
ATOM   165  O  OG1 . THR A 1 43  ? 5.61616   -11.29531 41.97455  1.000 41.61266  ? 23  THR D OG1 1 
ATOM   166  C  CG2 . THR A 1 43  ? 5.80042   -11.40412 39.56917  1.000 42.33175  ? 23  THR D CG2 1 
ATOM   167  N  N   . GLY A 1 44  ? 9.29144   -11.61463 39.42019  1.000 35.26786  ? 24  GLY D N   1 
ATOM   168  C  CA  . GLY A 1 44  ? 10.03099  -11.73785 38.17514  1.000 28.06827  ? 24  GLY D CA  1 
ATOM   169  C  C   . GLY A 1 44  ? 10.87193  -12.99705 38.11743  1.000 34.94695  ? 24  GLY D C   1 
ATOM   170  O  O   . GLY A 1 44  ? 10.95857  -13.64706 37.07325  1.000 35.50092  ? 24  GLY D O   1 
ATOM   171  N  N   . GLU A 1 45  ? 11.48632  -13.36744 39.24386  1.000 32.19251  ? 25  GLU D N   1 
ATOM   172  C  CA  . GLU A 1 45  ? 12.27917  -14.59182 39.30211  1.000 34.46249  ? 25  GLU D CA  1 
ATOM   173  C  C   . GLU A 1 45  ? 11.41197  -15.81814 39.03733  1.000 36.39862  ? 25  GLU D C   1 
ATOM   174  O  O   . GLU A 1 45  ? 11.77989  -16.69821 38.24587  1.000 35.47113  ? 25  GLU D O   1 
ATOM   175  C  CB  . GLU A 1 45  ? 12.96382  -14.68460 40.66679  1.000 31.25316  ? 25  GLU D CB  1 
ATOM   176  C  CG  . GLU A 1 45  ? 14.09512  -15.68096 40.76938  1.000 38.10623  ? 25  GLU D CG  1 
ATOM   177  C  CD  . GLU A 1 45  ? 14.88110  -15.51278 42.05713  1.000 50.38697  ? 25  GLU D CD  1 
ATOM   178  O  OE1 . GLU A 1 45  ? 14.27897  -15.12087 43.07901  1.000 40.78901  ? 25  GLU D OE1 1 
ATOM   179  O  OE2 . GLU A 1 45  ? 16.10738  -15.74773 42.04667  1.000 52.73749  ? 25  GLU D OE2 1 
ATOM   180  N  N   . VAL A 1 46  ? 10.24815  -15.88198 39.68995  1.000 32.55391  ? 26  VAL D N   1 
ATOM   181  C  CA  . VAL A 1 46  ? 9.33031   -17.00247 39.50797  1.000 27.28959  ? 26  VAL D CA  1 
ATOM   182  C  C   . VAL A 1 46  ? 8.88417   -17.09530 38.05545  1.000 32.82027  ? 26  VAL D C   1 
ATOM   183  O  O   . VAL A 1 46  ? 8.87932   -18.17817 37.45501  1.000 31.62489  ? 26  VAL D O   1 
ATOM   184  C  CB  . VAL A 1 46  ? 8.12632   -16.85810 40.45526  1.000 25.07416  ? 26  VAL D CB  1 
ATOM   185  C  CG1 . VAL A 1 46  ? 7.01888   -17.81534 40.04954  1.000 24.46808  ? 26  VAL D CG1 1 
ATOM   186  C  CG2 . VAL A 1 46  ? 8.54648   -17.10880 41.88242  1.000 20.36784  ? 26  VAL D CG2 1 
ATOM   187  N  N   . HIS A 1 47  ? 8.48837   -15.96095 37.47251  1.000 30.59575  ? 27  HIS D N   1 
ATOM   188  C  CA  . HIS A 1 47  ? 7.99451   -15.98372 36.10066  1.000 31.72202  ? 27  HIS D CA  1 
ATOM   189  C  C   . HIS A 1 47  ? 9.09406   -16.38007 35.12221  1.000 34.64114  ? 27  HIS D C   1 
ATOM   190  O  O   . HIS A 1 47  ? 8.83961   -17.12400 34.16651  1.000 28.62027  ? 27  HIS D O   1 
ATOM   191  C  CB  . HIS A 1 47  ? 7.40247   -14.62539 35.72984  1.000 25.92639  ? 27  HIS D CB  1 
ATOM   192  C  CG  . HIS A 1 47  ? 6.36468   -14.69814 34.65334  1.000 29.75022  ? 27  HIS D CG  1 
ATOM   193  N  ND1 . HIS A 1 47  ? 5.05551   -15.04867 34.90517  1.000 28.69897  ? 27  HIS D ND1 1 
ATOM   194  C  CD2 . HIS A 1 47  ? 6.44673   -14.48629 33.31854  1.000 33.05901  ? 27  HIS D CD2 1 
ATOM   195  C  CE1 . HIS A 1 47  ? 4.37335   -15.03939 33.77395  1.000 30.20021  ? 27  HIS D CE1 1 
ATOM   196  N  NE2 . HIS A 1 47  ? 5.19412   -14.70105 32.79595  1.000 38.86213  ? 27  HIS D NE2 1 
ATOM   197  N  N   . ALA A 1 48  ? 10.32373  -15.90408 35.34694  1.000 29.32876  ? 28  ALA D N   1 
ATOM   198  C  CA  . ALA A 1 48  ? 11.42752  -16.27045 34.46599  1.000 29.01854  ? 28  ALA D CA  1 
ATOM   199  C  C   . ALA A 1 48  ? 11.71934  -17.76232 34.54434  1.000 32.14030  ? 28  ALA D C   1 
ATOM   200  O  O   . ALA A 1 48  ? 11.92296  -18.41708 33.51475  1.000 32.48635  ? 28  ALA D O   1 
ATOM   201  C  CB  . ALA A 1 48  ? 12.67359  -15.45861 34.81991  1.000 19.57312  ? 28  ALA D CB  1 
ATOM   202  N  N   . MET A 1 49  ? 11.75259  -18.31243 35.76164  1.000 31.11286  ? 29  MET D N   1 
ATOM   203  C  CA  . MET A 1 49  ? 11.93383  -19.75144 35.93586  1.000 29.90677  ? 29  MET D CA  1 
ATOM   204  C  C   . MET A 1 49  ? 10.84977  -20.53730 35.20249  1.000 35.12817  ? 29  MET D C   1 
ATOM   205  O  O   . MET A 1 49  ? 11.14037  -21.49115 34.46112  1.000 31.23343  ? 29  MET D O   1 
ATOM   206  C  CB  . MET A 1 49  ? 11.93309  -20.08056 37.43152  1.000 32.90620  ? 29  MET D CB  1 
ATOM   207  C  CG  . MET A 1 49  ? 11.54525  -21.51014 37.77867  1.000 35.15616  ? 29  MET D CG  1 
ATOM   208  S  SD  . MET A 1 49  ? 12.83865  -22.68988 37.37559  1.000 63.95462  ? 29  MET D SD  1 
ATOM   209  C  CE  . MET A 1 49  ? 14.23436  -21.93447 38.19853  1.000 47.50927  ? 29  MET D CE  1 
ATOM   210  N  N   . LEU A 1 50  ? 9.58879   -20.14055 35.39790  1.000 29.81379  ? 30  LEU D N   1 
ATOM   211  C  CA  . LEU A 1 50  ? 8.47363   -20.84574 34.77717  1.000 29.48727  ? 30  LEU D CA  1 
ATOM   212  C  C   . LEU A 1 50  ? 8.57733   -20.81311 33.25765  1.000 31.85061  ? 30  LEU D C   1 
ATOM   213  O  O   . LEU A 1 50  ? 8.41924   -21.84251 32.59236  1.000 31.03780  ? 30  LEU D O   1 
ATOM   214  C  CB  . LEU A 1 50  ? 7.15159   -20.23493 35.24197  1.000 28.42267  ? 30  LEU D CB  1 
ATOM   215  C  CG  . LEU A 1 50  ? 5.87236   -20.90650 34.73660  1.000 28.97313  ? 30  LEU D CG  1 
ATOM   216  C  CD1 . LEU A 1 50  ? 5.81446   -22.35007 35.20146  1.000 24.91517  ? 30  LEU D CD1 1 
ATOM   217  C  CD2 . LEU A 1 50  ? 4.64630   -20.14101 35.20605  1.000 30.57382  ? 30  LEU D CD2 1 
ATOM   218  N  N   . CYS A 1 51  ? 8.85782   -19.63716 32.68864  1.000 33.29756  ? 31  CYS D N   1 
ATOM   219  C  CA  . CYS A 1 51  ? 8.90514   -19.51998 31.23448  1.000 32.61878  ? 31  CYS D CA  1 
ATOM   220  C  C   . CYS A 1 51  ? 10.11609  -20.22771 30.64246  1.000 32.08794  ? 31  CYS D C   1 
ATOM   221  O  O   . CYS A 1 51  ? 10.02598  -20.78300 29.53995  1.000 29.80401  ? 31  CYS D O   1 
ATOM   222  C  CB  . CYS A 1 51  ? 8.89140   -18.05008 30.82720  1.000 29.88421  ? 31  CYS D CB  1 
ATOM   223  S  SG  . CYS A 1 51  ? 7.31810   -17.24677 31.16544  1.000 32.50864  ? 31  CYS D SG  1 
ATOM   224  N  N   . ALA A 1 52  ? 11.24917  -20.23125 31.34827  1.000 28.88052  ? 32  ALA D N   1 
ATOM   225  C  CA  . ALA A 1 52  ? 12.40765  -20.96738 30.85519  1.000 37.64938  ? 32  ALA D CA  1 
ATOM   226  C  C   . ALA A 1 52  ? 12.12450  -22.46689 30.82247  1.000 33.55034  ? 32  ALA D C   1 
ATOM   227  O  O   . ALA A 1 52  ? 12.43032  -23.15011 29.83194  1.000 31.87664  ? 32  ALA D O   1 
ATOM   228  C  CB  . ALA A 1 52  ? 13.63487  -20.65164 31.71396  1.000 25.58232  ? 32  ALA D CB  1 
ATOM   229  N  N   . CYS A 1 53  ? 11.53073  -22.99759 31.89942  1.000 30.32133  ? 33  CYS D N   1 
ATOM   230  C  CA  . CYS A 1 53  ? 11.15203  -24.40781 31.90151  1.000 26.81345  ? 33  CYS D CA  1 
ATOM   231  C  C   . CYS A 1 53  ? 10.12733  -24.70366 30.81297  1.000 31.09291  ? 33  CYS D C   1 
ATOM   232  O  O   . CYS A 1 53  ? 10.19205  -25.75358 30.15766  1.000 33.59456  ? 33  CYS D O   1 
ATOM   233  C  CB  . CYS A 1 53  ? 10.60952  -24.80730 33.27310  1.000 32.76846  ? 33  CYS D CB  1 
ATOM   234  S  SG  . CYS A 1 53  ? 10.21638  -26.56796 33.44294  1.000 30.80393  ? 33  CYS D SG  1 
ATOM   235  N  N   . ASP A 1 54  ? 9.17524   -23.78816 30.60427  1.000 24.04656  ? 34  ASP D N   1 
ATOM   236  C  CA  . ASP A 1 54  ? 8.17810   -23.97708 29.55644  1.000 32.74309  ? 34  ASP D CA  1 
ATOM   237  C  C   . ASP A 1 54  ? 8.83624   -24.07593 28.18773  1.000 30.64212  ? 34  ASP D C   1 
ATOM   238  O  O   . ASP A 1 54  ? 8.50594   -24.96229 27.39356  1.000 38.41027  ? 34  ASP D O   1 
ATOM   239  C  CB  . ASP A 1 54  ? 7.16171   -22.83349 29.57528  1.000 31.11852  ? 34  ASP D CB  1 
ATOM   240  C  CG  . ASP A 1 54  ? 6.18523   -22.93231 30.72617  1.000 27.33964  ? 34  ASP D CG  1 
ATOM   241  O  OD1 . ASP A 1 54  ? 6.00914   -24.04066 31.26713  1.000 30.64700  ? 34  ASP D OD1 1 
ATOM   242  O  OD2 . ASP A 1 54  ? 5.59474   -21.89394 31.08780  1.000 33.85944  ? 34  ASP D OD2 1 
ATOM   243  N  N   . ALA A 1 55  ? 9.77070   -23.16725 27.89407  1.000 32.16509  ? 35  ALA D N   1 
ATOM   244  C  CA  . ALA A 1 55  ? 10.44754  -23.19546 26.60148  1.000 29.38953  ? 35  ALA D CA  1 
ATOM   245  C  C   . ALA A 1 55  ? 11.23021  -24.48922 26.41813  1.000 31.04788  ? 35  ALA D C   1 
ATOM   246  O  O   . ALA A 1 55  ? 11.17492  -25.10937 25.34690  1.000 33.85480  ? 35  ALA D O   1 
ATOM   247  C  CB  . ALA A 1 55  ? 11.36651  -21.98155 26.46034  1.000 28.42001  ? 35  ALA D CB  1 
ATOM   248  N  N   . HIS A 1 56  ? 11.95396  -24.92111 27.45704  1.000 31.56342  ? 36  HIS D N   1 
ATOM   249  C  CA  . HIS A 1 56  ? 12.72632  -26.15753 27.34912  1.000 30.89855  ? 36  HIS D CA  1 
ATOM   250  C  C   . HIS A 1 56  ? 11.82222  -27.35130 27.06512  1.000 35.30544  ? 36  HIS D C   1 
ATOM   251  O  O   . HIS A 1 56  ? 12.08757  -28.14556 26.15310  1.000 35.80200  ? 36  HIS D O   1 
ATOM   252  C  CB  . HIS A 1 56  ? 13.53177  -26.39620 28.62596  1.000 32.30649  ? 36  HIS D CB  1 
ATOM   253  C  CG  . HIS A 1 56  ? 14.59001  -27.44670 28.48281  1.000 31.10052  ? 36  HIS D CG  1 
ATOM   254  N  ND1 . HIS A 1 56  ? 14.33095  -28.79211 28.63297  1.000 34.13403  ? 36  HIS D ND1 1 
ATOM   255  C  CD2 . HIS A 1 56  ? 15.91055  -27.34823 28.19836  1.000 33.03247  ? 36  HIS D CD2 1 
ATOM   256  C  CE1 . HIS A 1 56  ? 15.44639  -29.47656 28.45144  1.000 33.10225  ? 36  HIS D CE1 1 
ATOM   257  N  NE2 . HIS A 1 56  ? 16.41974  -28.62412 28.18601  1.000 30.51996  ? 36  HIS D NE2 1 
ATOM   258  N  N   . GLN A 1 57  ? 10.74116  -27.49236 27.83615  1.000 35.84889  ? 37  GLN D N   1 
ATOM   259  C  CA  . GLN A 1 57  ? 9.87376   -28.65276 27.66803  1.000 31.03814  ? 37  GLN D CA  1 
ATOM   260  C  C   . GLN A 1 57  ? 9.11360   -28.60635 26.34737  1.000 33.71586  ? 37  GLN D C   1 
ATOM   261  O  O   . GLN A 1 57  ? 8.90083   -29.65306 25.72137  1.000 30.48373  ? 37  GLN D O   1 
ATOM   262  C  CB  . GLN A 1 57  ? 8.91540   -28.75526 28.85509  1.000 27.10432  ? 37  GLN D CB  1 
ATOM   263  C  CG  . GLN A 1 57  ? 9.63223   -29.06929 30.16673  1.000 37.02704  ? 37  GLN D CG  1 
ATOM   264  C  CD  . GLN A 1 57  ? 8.70709   -29.09019 31.36747  1.000 46.66172  ? 37  GLN D CD  1 
ATOM   265  O  OE1 . GLN A 1 57  ? 7.76393   -28.30216 31.45741  1.000 42.81285  ? 37  GLN D OE1 1 
ATOM   266  N  NE2 . GLN A 1 57  ? 8.97542   -29.99668 32.30167  1.000 43.13603  ? 37  GLN D NE2 1 
ATOM   267  N  N   . ALA A 1 58  ? 8.72412   -27.41164 25.89186  1.000 28.30877  ? 38  ALA D N   1 
ATOM   268  C  CA  . ALA A 1 58  ? 8.05000   -27.29661 24.60395  1.000 32.25372  ? 38  ALA D CA  1 
ATOM   269  C  C   . ALA A 1 58  ? 8.98642   -27.66075 23.45870  1.000 40.71131  ? 38  ALA D C   1 
ATOM   270  O  O   . ALA A 1 58  ? 8.57840   -28.34149 22.51023  1.000 42.81944  ? 38  ALA D O   1 
ATOM   271  C  CB  . ALA A 1 58  ? 7.49558   -25.88236 24.42738  1.000 28.62066  ? 38  ALA D CB  1 
ATOM   272  N  N   . ALA A 1 59  ? 10.24953  -27.23094 23.53105  1.000 37.00682  ? 39  ALA D N   1 
ATOM   273  C  CA  . ALA A 1 59  ? 11.21377  -27.64534 22.51713  1.000 32.93275  ? 39  ALA D CA  1 
ATOM   274  C  C   . ALA A 1 59  ? 11.45069  -29.14919 22.56270  1.000 36.73986  ? 39  ALA D C   1 
ATOM   275  O  O   . ALA A 1 59  ? 11.59133  -29.79406 21.51786  1.000 32.44214  ? 39  ALA D O   1 
ATOM   276  C  CB  . ALA A 1 59  ? 12.53174  -26.89458 22.69707  1.000 38.21622  ? 39  ALA D CB  1 
ATOM   277  N  N   . ALA A 1 60  ? 11.49962  -29.72931 23.76340  1.000 34.29710  ? 40  ALA D N   1 
ATOM   278  C  CA  . ALA A 1 60  ? 11.82301  -31.14728 23.86940  1.000 30.30609  ? 40  ALA D CA  1 
ATOM   279  C  C   . ALA A 1 60  ? 10.66139  -32.04806 23.47638  1.000 32.44218  ? 40  ALA D C   1 
ATOM   280  O  O   . ALA A 1 60  ? 10.89095  -33.20516 23.10764  1.000 41.17911  ? 40  ALA D O   1 
ATOM   281  C  CB  . ALA A 1 60  ? 12.27497  -31.48791 25.29212  1.000 27.26687  ? 40  ALA D CB  1 
ATOM   282  N  N   . SER A 1 61  ? 9.42606   -31.56044 23.55904  1.000 40.94213  ? 41  SER D N   1 
ATOM   283  C  CA  . SER A 1 61  ? 8.26119   -32.39253 23.29651  1.000 36.14380  ? 41  SER D CA  1 
ATOM   284  C  C   . SER A 1 61  ? 7.55886   -32.05422 21.98826  1.000 41.64819  ? 41  SER D C   1 
ATOM   285  O  O   . SER A 1 61  ? 6.52147   -32.65478 21.68531  1.000 41.71366  ? 41  SER D O   1 
ATOM   286  C  CB  . SER A 1 61  ? 7.26794   -32.28272 24.45748  1.000 38.79482  ? 41  SER D CB  1 
ATOM   287  O  OG  . SER A 1 61  ? 6.69188   -30.98882 24.50236  1.000 45.26280  ? 41  SER D OG  1 
ATOM   288  N  N   . GLY A 1 62  ? 8.08739   -31.11447 21.20752  1.000 46.91086  ? 42  GLY D N   1 
ATOM   289  C  CA  . GLY A 1 62  ? 7.43851   -30.73509 19.96872  1.000 32.88523  ? 42  GLY D CA  1 
ATOM   290  C  C   . GLY A 1 62  ? 6.12945   -30.00211 20.14033  1.000 48.25548  ? 42  GLY D C   1 
ATOM   291  O  O   . GLY A 1 62  ? 5.31845   -29.97459 19.21171  1.000 50.64476  ? 42  GLY D O   1 
ATOM   292  N  N   . THR A 1 63  ? 5.89563   -29.40894 21.30413  1.000 50.61128  ? 43  THR D N   1 
ATOM   293  C  CA  . THR A 1 63  ? 4.69355   -28.63759 21.57605  1.000 45.57107  ? 43  THR D CA  1 
ATOM   294  C  C   . THR A 1 63  ? 5.04042   -27.15295 21.63665  1.000 49.01003  ? 43  THR D C   1 
ATOM   295  O  O   . THR A 1 63  ? 6.20252   -26.75432 21.51672  1.000 44.95349  ? 43  THR D O   1 
ATOM   296  C  CB  . THR A 1 63  ? 4.03854   -29.10012 22.87947  1.000 43.42868  ? 43  THR D CB  1 
ATOM   297  O  OG1 . THR A 1 63  ? 4.92088   -28.83507 23.97701  1.000 50.35313  ? 43  THR D OG1 1 
ATOM   298  C  CG2 . THR A 1 63  ? 3.74243   -30.59193 22.82723  1.000 43.22690  ? 43  THR D CG2 1 
ATOM   299  N  N   . SER A 1 64  ? 4.01153   -26.33035 21.81999  1.000 48.64704  ? 44  SER D N   1 
ATOM   300  C  CA  . SER A 1 64  ? 4.17624   -24.89709 22.01154  1.000 48.73582  ? 44  SER D CA  1 
ATOM   301  C  C   . SER A 1 64  ? 3.97100   -24.55687 23.48146  1.000 48.85572  ? 44  SER D C   1 
ATOM   302  O  O   . SER A 1 64  ? 3.07272   -25.09641 24.13451  1.000 49.44762  ? 44  SER D O   1 
ATOM   303  C  CB  . SER A 1 64  ? 3.19423   -24.10519 21.14466  1.000 47.56974  ? 44  SER D CB  1 
ATOM   304  O  OG  . SER A 1 64  ? 1.85400   -24.34336 21.53792  1.000 59.78183  ? 44  SER D OG  1 
ATOM   305  N  N   . ALA A 1 65  ? 4.81033   -23.66458 23.99727  1.000 44.68613  ? 45  ALA D N   1 
ATOM   306  C  CA  . ALA A 1 65  ? 4.73575   -23.31050 25.40620  1.000 33.47780  ? 45  ALA D CA  1 
ATOM   307  C  C   . ALA A 1 65  ? 3.42215   -22.58994 25.69924  1.000 41.31392  ? 45  ALA D C   1 
ATOM   308  O  O   . ALA A 1 65  ? 2.95788   -21.78728 24.88388  1.000 45.96836  ? 45  ALA D O   1 
ATOM   309  C  CB  . ALA A 1 65  ? 5.91731   -22.42770 25.80349  1.000 26.37543  ? 45  ALA D CB  1 
ATOM   310  N  N   . PRO A 1 66  ? 2.79595   -22.85948 26.84171  1.000 50.13300  ? 46  PRO D N   1 
ATOM   311  C  CA  . PRO A 1 66  ? 1.54952   -22.16353 27.17185  1.000 49.01854  ? 46  PRO D CA  1 
ATOM   312  C  C   . PRO A 1 66  ? 1.79826   -20.69510 27.47474  1.000 45.66381  ? 46  PRO D C   1 
ATOM   313  O  O   . PRO A 1 66  ? 2.89356   -20.29425 27.87799  1.000 46.88369  ? 46  PRO D O   1 
ATOM   314  C  CB  . PRO A 1 66  ? 1.04219   -22.91147 28.41002  1.000 46.24632  ? 46  PRO D CB  1 
ATOM   315  C  CG  . PRO A 1 66  ? 2.26943   -23.48403 29.02904  1.000 41.61914  ? 46  PRO D CG  1 
ATOM   316  C  CD  . PRO A 1 66  ? 3.18577   -23.82551 27.88404  1.000 40.52569  ? 46  PRO D CD  1 
ATOM   317  N  N   . ALA A 1 67  ? 0.75981   -19.88998 27.26370  1.000 52.96228  ? 47  ALA D N   1 
ATOM   318  C  CA  . ALA A 1 67  ? 0.82270   -18.46195 27.54423  1.000 45.04992  ? 47  ALA D CA  1 
ATOM   319  C  C   . ALA A 1 67  ? 0.66303   -18.25463 29.04416  1.000 49.59674  ? 47  ALA D C   1 
ATOM   320  O  O   . ALA A 1 67  ? -0.40837  -18.51129 29.60063  1.000 57.42682  ? 47  ALA D O   1 
ATOM   321  C  CB  . ALA A 1 67  ? -0.25885  -17.71898 26.76477  1.000 52.69860  ? 47  ALA D CB  1 
ATOM   322  N  N   . ARG A 1 68  ? 1.71629   -17.77534 29.69790  1.000 45.66883  ? 48  ARG D N   1 
ATOM   323  C  CA  . ARG A 1 68  ? 1.70548   -17.58057 31.14079  1.000 46.95510  ? 48  ARG D CA  1 
ATOM   324  C  C   . ARG A 1 68  ? 1.32061   -16.14718 31.47557  1.000 39.28824  ? 48  ARG D C   1 
ATOM   325  O  O   . ARG A 1 68  ? 1.76193   -15.20064 30.81619  1.000 39.51748  ? 48  ARG D O   1 
ATOM   326  C  CB  . ARG A 1 68  ? 3.07348   -17.90771 31.74059  1.000 40.14229  ? 48  ARG D CB  1 
ATOM   327  C  CG  . ARG A 1 68  ? 3.53513   -19.33111 31.49121  1.000 38.20292  ? 48  ARG D CG  1 
ATOM   328  C  CD  . ARG A 1 68  ? 2.64542   -20.34493 32.19277  1.000 27.53785  ? 48  ARG D CD  1 
ATOM   329  N  NE  . ARG A 1 68  ? 3.22818   -21.68034 32.14803  1.000 37.90101  ? 48  ARG D NE  1 
ATOM   330  C  CZ  . ARG A 1 68  ? 2.70324   -22.75190 32.72634  1.000 31.33398  ? 48  ARG D CZ  1 
ATOM   331  N  NH1 . ARG A 1 68  ? 1.57273   -22.68506 33.40996  1.000 31.28233  ? 48  ARG D NH1 1 
ATOM   332  N  NH2 . ARG A 1 68  ? 3.32971   -23.92026 32.61649  1.000 36.38264  ? 48  ARG D NH2 1 
ATOM   333  N  N   . ARG A 1 69  ? 0.48943   -15.99737 32.50143  1.000 41.94764  ? 49  ARG D N   1 
ATOM   334  C  CA  . ARG A 1 69  ? 0.00058   -14.69705 32.93571  1.000 36.06174  ? 49  ARG D CA  1 
ATOM   335  C  C   . ARG A 1 69  ? 0.84797   -14.19989 34.09903  1.000 44.27316  ? 49  ARG D C   1 
ATOM   336  O  O   . ARG A 1 69  ? 0.92278   -14.85648 35.14442  1.000 44.05366  ? 49  ARG D O   1 
ATOM   337  C  CB  . ARG A 1 69  ? -1.46951  -14.77627 33.34390  1.000 40.55589  ? 49  ARG D CB  1 
ATOM   338  C  CG  . ARG A 1 69  ? -2.42419  -15.05186 32.19889  1.000 49.44693  ? 49  ARG D CG  1 
ATOM   339  C  CD  . ARG A 1 69  ? -3.82676  -15.32872 32.71880  1.000 56.02400  ? 49  ARG D CD  1 
ATOM   340  N  NE  . ARG A 1 69  ? -4.80491  -15.40265 31.64068  1.000 62.84338  ? 49  ARG D NE  1 
ATOM   341  C  CZ  . ARG A 1 69  ? -5.50176  -14.36755 31.19237  1.000 60.87571  ? 49  ARG D CZ  1 
ATOM   342  N  NH1 . ARG A 1 69  ? -5.35596  -13.15916 31.71165  1.000 60.97656  ? 49  ARG D NH1 1 
ATOM   343  N  NH2 . ARG A 1 69  ? -6.36642  -14.54894 30.19824  1.000 53.87714  ? 49  ARG D NH2 1 
ATOM   344  N  N   . MET A 1 70  ? 1.47509   -13.03490 33.91781  1.000 36.51485  ? 50  MET D N   1 
ATOM   345  C  CA  . MET A 1 70  ? 2.23026   -12.43018 35.00858  1.000 37.08782  ? 50  MET D CA  1 
ATOM   346  C  C   . MET A 1 70  ? 1.31555   -12.03816 36.16425  1.000 36.41570  ? 50  MET D C   1 
ATOM   347  O  O   . MET A 1 70  ? 1.75614   -11.99880 37.31951  1.000 32.92366  ? 50  MET D O   1 
ATOM   348  C  CB  . MET A 1 70  ? 3.00736   -11.21827 34.49238  1.000 49.61412  ? 50  MET D CB  1 
ATOM   349  C  CG  . MET A 1 70  ? 4.43628   -11.12281 35.00299  1.000 44.37765  ? 50  MET D CG  1 
ATOM   350  S  SD  . MET A 1 70  ? 5.35052   -9.80309  34.18161  1.000 84.69407  ? 50  MET D SD  1 
ATOM   351  C  CE  . MET A 1 70  ? 6.78367   -10.69559 33.57005  1.000 47.88804  ? 50  MET D CE  1 
ATOM   352  N  N   . GLU A 1 71  ? 0.04122   -11.75337 35.87318  1.000 36.76224  ? 51  GLU D N   1 
ATOM   353  C  CA  . GLU A 1 71  ? -0.92951  -11.48165 36.93103  1.000 41.63013  ? 51  GLU D CA  1 
ATOM   354  C  C   . GLU A 1 71  ? -1.09758  -12.69004 37.84274  1.000 32.10770  ? 51  GLU D C   1 
ATOM   355  O  O   . GLU A 1 71  ? -1.14226  -12.55053 39.07093  1.000 30.11594  ? 51  GLU D O   1 
ATOM   356  C  CB  . GLU A 1 71  ? -2.28396  -11.09448 36.32937  1.000 42.26546  ? 51  GLU D CB  1 
ATOM   357  C  CG  . GLU A 1 71  ? -2.23930  -10.10973 35.16252  1.000 42.81398  ? 51  GLU D CG  1 
ATOM   358  C  CD  . GLU A 1 71  ? -1.95938  -10.77571 33.82645  1.000 45.81349  ? 51  GLU D CD  1 
ATOM   359  O  OE1 . GLU A 1 71  ? -0.83674  -11.28848 33.64287  1.000 48.74932  ? 51  GLU D OE1 1 
ATOM   360  O  OE2 . GLU A 1 71  ? -2.86440  -10.79375 32.96462  1.000 52.34690  ? 51  GLU D OE2 1 
ATOM   361  N  N   . THR A 1 72  ? -1.20843  -13.88571 37.25342  1.000 39.89075  ? 52  THR D N   1 
ATOM   362  C  CA  . THR A 1 72  ? -1.30669  -15.10777 38.04667  1.000 32.33640  ? 52  THR D CA  1 
ATOM   363  C  C   . THR A 1 72  ? -0.05966  -15.30624 38.90183  1.000 33.16225  ? 52  THR D C   1 
ATOM   364  O  O   . THR A 1 72  ? -0.15677  -15.68152 40.07620  1.000 30.49405  ? 52  THR D O   1 
ATOM   365  C  CB  . THR A 1 72  ? -1.52935  -16.31437 37.12870  1.000 37.38864  ? 52  THR D CB  1 
ATOM   366  O  OG1 . THR A 1 72  ? -2.51451  -15.99176 36.13961  1.000 37.63489  ? 52  THR D OG1 1 
ATOM   367  C  CG2 . THR A 1 72  ? -2.00559  -17.52446 37.92594  1.000 34.30944  ? 52  THR D CG2 1 
ATOM   368  N  N   . THR A 1 73  ? 1.12193   -15.05782 38.32787  1.000 34.66922  ? 53  THR D N   1 
ATOM   369  C  CA  . THR A 1 73  ? 2.36351   -15.15712 39.09292  1.000 33.47219  ? 53  THR D CA  1 
ATOM   370  C  C   . THR A 1 73  ? 2.34758   -14.20998 40.28738  1.000 32.87125  ? 53  THR D C   1 
ATOM   371  O  O   . THR A 1 73  ? 2.67650   -14.60470 41.41304  1.000 36.81811  ? 53  THR D O   1 
ATOM   372  C  CB  . THR A 1 73  ? 3.56745   -14.86298 38.19005  1.000 37.04073  ? 53  THR D CB  1 
ATOM   373  O  OG1 . THR A 1 73  ? 3.57780   -15.77560 37.08561  1.000 32.39434  ? 53  THR D OG1 1 
ATOM   374  C  CG2 . THR A 1 73  ? 4.87797   -15.00315 38.96290  1.000 30.47086  ? 53  THR D CG2 1 
ATOM   375  N  N   . GLU A 1 74  ? 1.96890   -12.94943 40.05575  1.000 29.84638  ? 54  GLU D N   1 
ATOM   376  C  CA  . GLU A 1 74  ? 1.89256   -11.98122 41.14574  1.000 34.60278  ? 54  GLU D CA  1 
ATOM   377  C  C   . GLU A 1 74  ? 0.91595   -12.43523 42.22250  1.000 38.00003  ? 54  GLU D C   1 
ATOM   378  O  O   . GLU A 1 74  ? 1.21805   -12.35342 43.41889  1.000 40.53567  ? 54  GLU D O   1 
ATOM   379  C  CB  . GLU A 1 74  ? 1.49039   -10.61054 40.60324  1.000 37.80042  ? 54  GLU D CB  1 
ATOM   380  C  CG  . GLU A 1 74  ? 2.55145   -9.95017  39.73776  1.000 48.69332  ? 54  GLU D CG  1 
ATOM   381  C  CD  . GLU A 1 74  ? 2.11754   -8.59653  39.21843  1.000 44.87810  ? 54  GLU D CD  1 
ATOM   382  O  OE1 . GLU A 1 74  ? 0.91020   -8.42289  38.94773  1.000 37.55019  ? 54  GLU D OE1 1 
ATOM   383  O  OE2 . GLU A 1 74  ? 2.98328   -7.70681  39.08682  1.000 47.75437  ? 54  GLU D OE2 1 
ATOM   384  N  N   . HIS A 1 75  ? -0.25541  -12.93160 41.81718  1.000 35.43785  ? 55  HIS D N   1 
ATOM   385  C  CA  . HIS A 1 75  ? -1.24429  -13.37224 42.79623  1.000 38.65497  ? 55  HIS D CA  1 
ATOM   386  C  C   . HIS A 1 75  ? -0.72799  -14.54869 43.61763  1.000 41.30587  ? 55  HIS D C   1 
ATOM   387  O  O   . HIS A 1 75  ? -0.87104  -14.56544 44.84595  1.000 43.53139  ? 55  HIS D O   1 
ATOM   388  C  CB  . HIS A 1 75  ? -2.55642  -13.73535 42.09922  1.000 35.95807  ? 55  HIS D CB  1 
ATOM   389  C  CG  . HIS A 1 75  ? -3.57115  -14.35237 43.01079  1.000 57.97387  ? 55  HIS D CG  1 
ATOM   390  N  ND1 . HIS A 1 75  ? -3.78506  -15.71293 43.07213  1.000 57.11595  ? 55  HIS D ND1 1 
ATOM   391  C  CD2 . HIS A 1 75  ? -4.42175  -13.79658 43.90634  1.000 65.88926  ? 55  HIS D CD2 1 
ATOM   392  C  CE1 . HIS A 1 75  ? -4.72708  -15.96842 43.96222  1.000 60.65500  ? 55  HIS D CE1 1 
ATOM   393  N  NE2 . HIS A 1 75  ? -5.13047  -14.82289 44.48239  1.000 73.62216  ? 55  HIS D NE2 1 
ATOM   394  N  N   . ARG A 1 76  ? -0.11316  -15.53736 42.96244  1.000 40.00644  ? 56  ARG D N   1 
ATOM   395  C  CA  . ARG A 1 76  ? 0.36878   -16.70896 43.69018  1.000 41.03233  ? 56  ARG D CA  1 
ATOM   396  C  C   . ARG A 1 76  ? 1.52472   -16.35305 44.61908  1.000 34.80219  ? 56  ARG D C   1 
ATOM   397  O  O   . ARG A 1 76  ? 1.60582   -16.86895 45.74073  1.000 29.53749  ? 56  ARG D O   1 
ATOM   398  C  CB  . ARG A 1 76  ? 0.78528   -17.80982 42.71420  1.000 38.38789  ? 56  ARG D CB  1 
ATOM   399  C  CG  . ARG A 1 76  ? -0.34634  -18.34456 41.85650  1.000 34.77694  ? 56  ARG D CG  1 
ATOM   400  C  CD  . ARG A 1 76  ? -1.55440  -18.72370 42.69949  1.000 29.25350  ? 56  ARG D CD  1 
ATOM   401  N  NE  . ARG A 1 76  ? -2.64399  -19.21890 41.86817  1.000 36.77764  ? 56  ARG D NE  1 
ATOM   402  C  CZ  . ARG A 1 76  ? -3.87731  -19.44242 42.29962  1.000 33.24130  ? 56  ARG D CZ  1 
ATOM   403  N  NH1 . ARG A 1 76  ? -4.21992  -19.22331 43.55854  1.000 36.94479  ? 56  ARG D NH1 1 
ATOM   404  N  NH2 . ARG A 1 76  ? -4.79142  -19.89216 41.44461  1.000 34.79683  ? 56  ARG D NH2 1 
ATOM   405  N  N   . VAL A 1 77  ? 2.42686   -15.47336 44.17556  1.000 34.56555  ? 57  VAL D N   1 
ATOM   406  C  CA  . VAL A 1 77  ? 3.55065   -15.07737 45.01950  1.000 39.78132  ? 57  VAL D CA  1 
ATOM   407  C  C   . VAL A 1 77  ? 3.06418   -14.26498 46.21602  1.000 32.72513  ? 57  VAL D C   1 
ATOM   408  O  O   . VAL A 1 77  ? 3.52404   -14.46678 47.34652  1.000 30.71041  ? 57  VAL D O   1 
ATOM   409  C  CB  . VAL A 1 77  ? 4.59648   -14.30846 44.18849  1.000 30.99471  ? 57  VAL D CB  1 
ATOM   410  C  CG1 . VAL A 1 77  ? 5.64302   -13.68097 45.09112  1.000 38.60871  ? 57  VAL D CG1 1 
ATOM   411  C  CG2 . VAL A 1 77  ? 5.26636   -15.23662 43.18358  1.000 29.04315  ? 57  VAL D CG2 1 
ATOM   412  N  N   . ARG A 1 78  ? 2.11685   -13.34768 45.99286  1.000 37.84851  ? 58  ARG D N   1 
ATOM   413  C  CA  . ARG A 1 78  ? 1.60022   -12.52430 47.08399  1.000 40.49522  ? 58  ARG D CA  1 
ATOM   414  C  C   . ARG A 1 78  ? 0.91525   -13.36240 48.15479  1.000 40.53044  ? 58  ARG D C   1 
ATOM   415  O  O   . ARG A 1 78  ? 0.95649   -13.00923 49.33931  1.000 42.65315  ? 58  ARG D O   1 
ATOM   416  C  CB  . ARG A 1 78  ? 0.62539   -11.47889 46.54012  1.000 46.81880  ? 58  ARG D CB  1 
ATOM   417  C  CG  . ARG A 1 78  ? 1.23467   -10.11083 46.28420  1.000 53.88608  ? 58  ARG D CG  1 
ATOM   418  C  CD  . ARG A 1 78  ? 2.51621   -10.21232 45.47796  1.000 63.60531  ? 58  ARG D CD  1 
ATOM   419  N  NE  . ARG A 1 78  ? 2.68100   -9.07432  44.58350  1.000 77.78798  ? 58  ARG D NE  1 
ATOM   420  C  CZ  . ARG A 1 78  ? 3.71451   -8.90452  43.77175  1.000 68.10133  ? 58  ARG D CZ  1 
ATOM   421  N  NH1 . ARG A 1 78  ? 4.71603   -9.76896  43.73768  1.000 61.97852  ? 58  ARG D NH1 1 
ATOM   422  N  NH2 . ARG A 1 78  ? 3.74054   -7.84424  42.97024  1.000 67.45925  ? 58  ARG D NH2 1 
ATOM   423  N  N   . SER A 1 79  ? 0.28406   -14.46742 47.76484  1.000 33.87893  ? 59  SER D N   1 
ATOM   424  C  CA  . SER A 1 79  ? -0.42265  -15.32239 48.70875  1.000 35.71011  ? 59  SER D CA  1 
ATOM   425  C  C   . SER A 1 79  ? 0.49422   -16.28799 49.44798  1.000 37.55877  ? 59  SER D C   1 
ATOM   426  O  O   . SER A 1 79  ? 0.01279   -17.02813 50.31181  1.000 39.71538  ? 59  SER D O   1 
ATOM   427  C  CB  . SER A 1 79  ? -1.51198  -16.11462 47.97990  1.000 30.50247  ? 59  SER D CB  1 
ATOM   428  O  OG  . SER A 1 79  ? -2.38542  -15.24683 47.27835  1.000 53.14807  ? 59  SER D OG  1 
ATOM   429  N  N   . GLY A 1 80  ? 1.78904   -16.30110 49.14242  1.000 35.19836  ? 60  GLY D N   1 
ATOM   430  C  CA  . GLY A 1 80  ? 2.67343   -17.28636 49.73444  1.000 28.17603  ? 60  GLY D CA  1 
ATOM   431  C  C   . GLY A 1 80  ? 2.43570   -18.69530 49.23913  1.000 38.83534  ? 60  GLY D C   1 
ATOM   432  O  O   . GLY A 1 80  ? 2.66926   -19.65390 49.98104  1.000 34.69416  ? 60  GLY D O   1 
ATOM   433  N  N   . SER A 1 81  ? 1.97841   -18.84578 47.99560  1.000 30.35695  ? 61  SER D N   1 
ATOM   434  C  CA  . SER A 1 81  ? 1.65059   -20.14251 47.42002  1.000 30.25685  ? 61  SER D CA  1 
ATOM   435  C  C   . SER A 1 81  ? 2.76952   -20.72184 46.56299  1.000 41.12441  ? 61  SER D C   1 
ATOM   436  O  O   . SER A 1 81  ? 2.63744   -21.85557 46.08979  1.000 30.34623  ? 61  SER D O   1 
ATOM   437  C  CB  . SER A 1 81  ? 0.36959   -20.03897 46.58260  1.000 31.67681  ? 61  SER D CB  1 
ATOM   438  O  OG  . SER A 1 81  ? -0.71013  -19.53306 47.34855  1.000 43.95402  ? 61  SER D OG  1 
ATOM   439  N  N   . VAL A 1 82  ? 3.85630   -19.98123 46.34865  1.000 32.61746  ? 62  VAL D N   1 
ATOM   440  C  CA  . VAL A 1 82  ? 4.94619   -20.40176 45.47358  1.000 31.61569  ? 62  VAL D CA  1 
ATOM   441  C  C   . VAL A 1 82  ? 6.12124   -20.82447 46.34548  1.000 29.28810  ? 62  VAL D C   1 
ATOM   442  O  O   . VAL A 1 82  ? 6.72588   -19.99662 47.03895  1.000 32.32027  ? 62  VAL D O   1 
ATOM   443  C  CB  . VAL A 1 82  ? 5.35543   -19.28947 44.49928  1.000 31.55730  ? 62  VAL D CB  1 
ATOM   444  C  CG1 . VAL A 1 82  ? 6.39392   -19.79862 43.50869  1.000 26.61842  ? 62  VAL D CG1 1 
ATOM   445  C  CG2 . VAL A 1 82  ? 4.13566   -18.74961 43.76921  1.000 25.73555  ? 62  VAL D CG2 1 
ATOM   446  N  N   . HIS A 1 83  ? 6.45734   -22.10965 46.29952  1.000 31.66914  ? 63  HIS D N   1 
ATOM   447  C  CA  . HIS A 1 83  ? 7.59241   -22.65248 47.03177  1.000 33.66975  ? 63  HIS D CA  1 
ATOM   448  C  C   . HIS A 1 83  ? 8.72715   -22.89318 46.04336  1.000 33.62620  ? 63  HIS D C   1 
ATOM   449  O  O   . HIS A 1 83  ? 8.54417   -23.59408 45.03883  1.000 31.97999  ? 63  HIS D O   1 
ATOM   450  C  CB  . HIS A 1 83  ? 7.20488   -23.94149 47.75366  1.000 29.11428  ? 63  HIS D CB  1 
ATOM   451  C  CG  . HIS A 1 83  ? 6.03070   -23.78598 48.66976  1.000 39.27167  ? 63  HIS D CG  1 
ATOM   452  N  ND1 . HIS A 1 83  ? 6.15155   -23.79451 50.04310  1.000 46.33569  ? 63  HIS D ND1 1 
ATOM   453  C  CD2 . HIS A 1 83  ? 4.71346   -23.60624 48.40901  1.000 32.90662  ? 63  HIS D CD2 1 
ATOM   454  C  CE1 . HIS A 1 83  ? 4.95901   -23.63334 50.58874  1.000 39.09740  ? 63  HIS D CE1 1 
ATOM   455  N  NE2 . HIS A 1 83  ? 4.06935   -23.51555 49.61911  1.000 34.98137  ? 63  HIS D NE2 1 
ATOM   456  N  N   . LEU A 1 84  ? 9.88905   -22.30471 46.32426  1.000 34.58883  ? 64  LEU D N   1 
ATOM   457  C  CA  . LEU A 1 84  ? 11.02256  -22.30142 45.40961  1.000 31.61982  ? 64  LEU D CA  1 
ATOM   458  C  C   . LEU A 1 84  ? 12.23773  -22.93723 46.07367  1.000 31.79330  ? 64  LEU D C   1 
ATOM   459  O  O   . LEU A 1 84  ? 12.54180  -22.65216 47.23793  1.000 30.54530  ? 64  LEU D O   1 
ATOM   460  C  CB  . LEU A 1 84  ? 11.34320  -20.87400 44.95133  1.000 27.42652  ? 64  LEU D CB  1 
ATOM   461  C  CG  . LEU A 1 84  ? 12.39778  -20.71927 43.85604  1.000 32.12650  ? 64  LEU D CG  1 
ATOM   462  C  CD1 . LEU A 1 84  ? 11.94848  -19.71492 42.80956  1.000 31.85369  ? 64  LEU D CD1 1 
ATOM   463  C  CD2 . LEU A 1 84  ? 13.70305  -20.28224 44.47253  1.000 34.42807  ? 64  LEU D CD2 1 
ATOM   464  N  N   . LEU A 1 85  ? 12.92340  -23.79670 45.32317  1.000 33.43391  ? 65  LEU D N   1 
ATOM   465  C  CA  . LEU A 1 85  ? 14.13452  -24.48492 45.74667  1.000 30.74227  ? 65  LEU D CA  1 
ATOM   466  C  C   . LEU A 1 85  ? 15.32150  -23.87842 45.01158  1.000 36.42615  ? 65  LEU D C   1 
ATOM   467  O  O   . LEU A 1 85  ? 15.36101  -23.89689 43.77249  1.000 31.39668  ? 65  LEU D O   1 
ATOM   468  C  CB  . LEU A 1 85  ? 14.03553  -25.98350 45.45614  1.000 28.18914  ? 65  LEU D CB  1 
ATOM   469  C  CG  . LEU A 1 85  ? 15.31666  -26.81617 45.57240  1.000 36.02048  ? 65  LEU D CG  1 
ATOM   470  C  CD1 . LEU A 1 85  ? 15.80253  -26.86085 47.01415  1.000 36.49822  ? 65  LEU D CD1 1 
ATOM   471  C  CD2 . LEU A 1 85  ? 15.12714  -28.22759 45.01846  1.000 27.81621  ? 65  LEU D CD2 1 
ATOM   472  N  N   . ARG A 1 86  ? 16.27935  -23.35875 45.78041  1.000 30.19008  ? 66  ARG D N   1 
ATOM   473  C  CA  . ARG A 1 86  ? 17.50379  -22.74511 45.29247  1.000 31.01303  ? 66  ARG D CA  1 
ATOM   474  C  C   . ARG A 1 86  ? 18.69142  -23.67693 45.48690  1.000 37.20678  ? 66  ARG D C   1 
ATOM   475  O  O   . ARG A 1 86  ? 18.75182  -24.44915 46.45238  1.000 39.14754  ? 66  ARG D O   1 
ATOM   476  C  CB  . ARG A 1 86  ? 17.80707  -21.43585 46.02746  1.000 29.61819  ? 66  ARG D CB  1 
ATOM   477  C  CG  . ARG A 1 86  ? 16.99388  -20.24695 45.59504  1.000 35.82972  ? 66  ARG D CG  1 
ATOM   478  C  CD  . ARG A 1 86  ? 17.41953  -19.00707 46.36154  1.000 31.83596  ? 66  ARG D CD  1 
ATOM   479  N  NE  . ARG A 1 86  ? 16.41921  -17.95344 46.26434  1.000 39.41060  ? 66  ARG D NE  1 
ATOM   480  C  CZ  . ARG A 1 86  ? 16.29349  -17.13609 45.22871  1.000 37.64265  ? 66  ARG D CZ  1 
ATOM   481  N  NH1 . ARG A 1 86  ? 17.10036  -17.21573 44.18280  1.000 28.08541  ? 66  ARG D NH1 1 
ATOM   482  N  NH2 . ARG A 1 86  ? 15.33153  -16.21859 45.24058  1.000 33.97426  ? 66  ARG D NH2 1 
ATOM   483  N  N   . HIS A 1 87  ? 19.65113  -23.56034 44.57006  1.000 31.31167  ? 67  HIS D N   1 
ATOM   484  C  CA  . HIS A 1 87  ? 20.94205  -24.23578 44.65613  1.000 33.57917  ? 67  HIS D CA  1 
ATOM   485  C  C   . HIS A 1 87  ? 22.02580  -23.17194 44.53994  1.000 40.20775  ? 67  HIS D C   1 
ATOM   486  O  O   . HIS A 1 87  ? 22.16534  -22.54002 43.48610  1.000 37.46136  ? 67  HIS D O   1 
ATOM   487  C  CB  . HIS A 1 87  ? 21.09225  -25.29052 43.55923  1.000 33.38600  ? 67  HIS D CB  1 
ATOM   488  C  CG  . HIS A 1 87  ? 22.42715  -25.96726 43.55010  1.000 48.51254  ? 67  HIS D CG  1 
ATOM   489  N  ND1 . HIS A 1 87  ? 22.79777  -26.89674 44.49837  1.000 48.10170  ? 67  HIS D ND1 1 
ATOM   490  C  CD2 . HIS A 1 87  ? 23.48098  -25.84750 42.70844  1.000 42.95648  ? 67  HIS D CD2 1 
ATOM   491  C  CE1 . HIS A 1 87  ? 24.02160  -27.32160 44.23978  1.000 42.60719  ? 67  HIS D CE1 1 
ATOM   492  N  NE2 . HIS A 1 87  ? 24.45809  -26.70149 43.15827  1.000 39.26554  ? 67  HIS D NE2 1 
ATOM   493  N  N   . ASP A 1 88  ? 22.78118  -22.97059 45.62315  1.000 34.66705  ? 68  ASP D N   1 
ATOM   494  C  CA  . ASP A 1 88  ? 23.81552  -21.93567 45.68912  1.000 32.23889  ? 68  ASP D CA  1 
ATOM   495  C  C   . ASP A 1 88  ? 23.24794  -20.56193 45.33854  1.000 37.94457  ? 68  ASP D C   1 
ATOM   496  O  O   . ASP A 1 88  ? 23.88896  -19.75390 44.66348  1.000 34.69785  ? 68  ASP D O   1 
ATOM   497  C  CB  . ASP A 1 88  ? 25.00352  -22.27905 44.78796  1.000 38.01417  ? 68  ASP D CB  1 
ATOM   498  C  CG  . ASP A 1 88  ? 25.77829  -23.48667 45.27883  1.000 42.27597  ? 68  ASP D CG  1 
ATOM   499  O  OD1 . ASP A 1 88  ? 25.80495  -23.72081 46.50668  1.000 42.43047  ? 68  ASP D OD1 1 
ATOM   500  O  OD2 . ASP A 1 88  ? 26.36237  -24.19982 44.43701  1.000 49.41838  ? 68  ASP D OD2 1 
ATOM   501  N  N   . GLY A 1 89  ? 22.02567  -20.29543 45.80075  1.000 31.94832  ? 69  GLY D N   1 
ATOM   502  C  CA  . GLY A 1 89  ? 21.37233  -19.02682 45.57656  1.000 36.16999  ? 69  GLY D CA  1 
ATOM   503  C  C   . GLY A 1 89  ? 20.59485  -18.91904 44.28066  1.000 33.90329  ? 69  GLY D C   1 
ATOM   504  O  O   . GLY A 1 89  ? 19.73136  -18.04224 44.16565  1.000 33.85730  ? 69  GLY D O   1 
ATOM   505  N  N   . ARG A 1 90  ? 20.87335  -19.77839 43.30397  1.000 35.60782  ? 70  ARG D N   1 
ATOM   506  C  CA  . ARG A 1 90  ? 20.18453  -19.73180 42.02006  1.000 40.47490  ? 70  ARG D CA  1 
ATOM   507  C  C   . ARG A 1 90  ? 18.97610  -20.66594 42.02593  1.000 34.26787  ? 70  ARG D C   1 
ATOM   508  O  O   . ARG A 1 90  ? 19.06240  -21.79171 42.52718  1.000 37.88183  ? 70  ARG D O   1 
ATOM   509  C  CB  . ARG A 1 90  ? 21.13092  -20.12041 40.88891  1.000 41.32327  ? 70  ARG D CB  1 
ATOM   510  C  CG  . ARG A 1 90  ? 21.89307  -18.94509 40.29509  1.000 49.84921  ? 70  ARG D CG  1 
ATOM   511  C  CD  . ARG A 1 90  ? 23.17361  -19.39280 39.60519  1.000 48.56257  ? 70  ARG D CD  1 
ATOM   512  N  NE  . ARG A 1 90  ? 23.06970  -20.74186 39.06216  1.000 58.96736  ? 70  ARG D NE  1 
ATOM   513  C  CZ  . ARG A 1 90  ? 22.51197  -21.04315 37.89725  1.000 57.98855  ? 70  ARG D CZ  1 
ATOM   514  N  NH1 . ARG A 1 90  ? 21.97037  -20.11254 37.12830  1.000 44.99629  ? 70  ARG D NH1 1 
ATOM   515  N  NH2 . ARG A 1 90  ? 22.49091  -22.31147 37.49711  1.000 55.48696  ? 70  ARG D NH2 1 
ATOM   516  N  N   . PRO A 1 91  ? 17.84561  -20.21848 41.48022  1.000 35.55197  ? 71  PRO D N   1 
ATOM   517  C  CA  . PRO A 1 91  ? 16.62438  -21.03462 41.54022  1.000 41.09043  ? 71  PRO D CA  1 
ATOM   518  C  C   . PRO A 1 91  ? 16.77540  -22.30819 40.72075  1.000 33.40381  ? 71  PRO D C   1 
ATOM   519  O  O   . PRO A 1 91  ? 17.14252  -22.26808 39.54441  1.000 36.68215  ? 71  PRO D O   1 
ATOM   520  C  CB  . PRO A 1 91  ? 15.54556  -20.11029 40.95918  1.000 31.82600  ? 71  PRO D CB  1 
ATOM   521  C  CG  . PRO A 1 91  ? 16.13370  -18.73026 41.01925  1.000 31.59435  ? 71  PRO D CG  1 
ATOM   522  C  CD  . PRO A 1 91  ? 17.60724  -18.90942 40.85109  1.000 34.92099  ? 71  PRO D CD  1 
ATOM   523  N  N   . ALA A 1 92  ? 16.49832  -23.44277 41.35854  1.000 33.17033  ? 72  ALA D N   1 
ATOM   524  C  CA  . ALA A 1 92  ? 16.58612  -24.74966 40.71937  1.000 32.87011  ? 72  ALA D CA  1 
ATOM   525  C  C   . ALA A 1 92  ? 15.22925  -25.35419 40.40372  1.000 39.06127  ? 72  ALA D C   1 
ATOM   526  O  O   . ALA A 1 92  ? 15.07190  -25.99350 39.36002  1.000 34.92384  ? 72  ALA D O   1 
ATOM   527  C  CB  . ALA A 1 92  ? 17.37873  -25.72173 41.60387  1.000 28.10600  ? 72  ALA D CB  1 
ATOM   528  N  N   . GLY A 1 93  ? 14.24561  -25.17325 41.28277  1.000 31.72749  ? 73  GLY D N   1 
ATOM   529  C  CA  . GLY A 1 93  ? 12.91642  -25.69889 41.01721  1.000 30.27143  ? 73  GLY D CA  1 
ATOM   530  C  C   . GLY A 1 93  ? 11.87519  -24.93052 41.79694  1.000 31.79919  ? 73  GLY D C   1 
ATOM   531  O  O   . GLY A 1 93  ? 12.19995  -24.06534 42.61114  1.000 28.03584  ? 73  GLY D O   1 
ATOM   532  N  N   . MET A 1 94  ? 10.60809  -25.26049 41.54908  1.000 19.05803  ? 74  MET D N   1 
ATOM   533  C  CA  . MET A 1 94  ? 9.52707   -24.62610 42.29616  1.000 29.68988  ? 74  MET D CA  1 
ATOM   534  C  C   . MET A 1 94  ? 8.20644   -25.32022 41.99711  1.000 27.17981  ? 74  MET D C   1 
ATOM   535  O  O   . MET A 1 94  ? 8.09162   -26.13036 41.07176  1.000 27.09244  ? 74  MET D O   1 
ATOM   536  C  CB  . MET A 1 94  ? 9.40546   -23.13663 41.96652  1.000 31.68187  ? 74  MET D CB  1 
ATOM   537  C  CG  . MET A 1 94  ? 8.89366   -22.86486 40.56686  1.000 25.06067  ? 74  MET D CG  1 
ATOM   538  S  SD  . MET A 1 94  ? 8.40117   -21.15111 40.38712  1.000 24.39132  ? 74  MET D SD  1 
ATOM   539  C  CE  . MET A 1 94  ? 8.05964   -21.09076 38.63513  1.000 20.62784  ? 74  MET D CE  1 
ATOM   540  N  N   . PHE A 1 95  ? 7.20177   -24.95776 42.79134  1.000 27.62211  ? 75  PHE D N   1 
ATOM   541  C  CA  . PHE A 1 95  ? 5.82152   -25.35533 42.54511  1.000 30.21874  ? 75  PHE D CA  1 
ATOM   542  C  C   . PHE A 1 95  ? 4.90365   -24.33360 43.20263  1.000 30.43382  ? 75  PHE D C   1 
ATOM   543  O  O   . PHE A 1 95  ? 5.34686   -23.48500 43.98184  1.000 26.73906  ? 75  PHE D O   1 
ATOM   544  C  CB  . PHE A 1 95  ? 5.54364   -26.77478 43.05293  1.000 25.40880  ? 75  PHE D CB  1 
ATOM   545  C  CG  . PHE A 1 95  ? 5.73566   -26.94659 44.53372  1.000 34.84582  ? 75  PHE D CG  1 
ATOM   546  C  CD1 . PHE A 1 95  ? 4.67483   -26.76989 45.40919  1.000 27.83625  ? 75  PHE D CD1 1 
ATOM   547  C  CD2 . PHE A 1 95  ? 6.97359   -27.29806 45.05047  1.000 26.12535  ? 75  PHE D CD2 1 
ATOM   548  C  CE1 . PHE A 1 95  ? 4.84791   -26.92982 46.77232  1.000 30.65030  ? 75  PHE D CE1 1 
ATOM   549  C  CE2 . PHE A 1 95  ? 7.14968   -27.46126 46.41359  1.000 27.26854  ? 75  PHE D CE2 1 
ATOM   550  C  CZ  . PHE A 1 95  ? 6.08611   -27.27639 47.27342  1.000 24.79313  ? 75  PHE D CZ  1 
ATOM   551  N  N   . THR A 1 96  ? 3.61364   -24.42136 42.87119  1.000 30.85248  ? 76  THR D N   1 
ATOM   552  C  CA  . THR A 1 96  ? 2.57255   -23.59826 43.46770  1.000 26.49359  ? 76  THR D CA  1 
ATOM   553  C  C   . THR A 1 96  ? 1.53965   -24.52611 44.08680  1.000 29.57030  ? 76  THR D C   1 
ATOM   554  O  O   . THR A 1 96  ? 1.04163   -25.43883 43.41871  1.000 30.92821  ? 76  THR D O   1 
ATOM   555  C  CB  . THR A 1 96  ? 1.91798   -22.67898 42.42719  1.000 29.30539  ? 76  THR D CB  1 
ATOM   556  O  OG1 . THR A 1 96  ? 2.86660   -21.70444 41.97189  1.000 33.35323  ? 76  THR D OG1 1 
ATOM   557  C  CG2 . THR A 1 96  ? 0.70440   -21.96474 43.01228  1.000 27.12131  ? 76  THR D CG2 1 
ATOM   558  N  N   . LEU A 1 97  ? 1.24113   -24.30697 45.36423  1.000 26.72748  ? 77  LEU D N   1 
ATOM   559  C  CA  . LEU A 1 97  ? 0.33663   -25.15738 46.12722  1.000 25.29904  ? 77  LEU D CA  1 
ATOM   560  C  C   . LEU A 1 97  ? -0.77850  -24.29113 46.69076  1.000 31.10522  ? 77  LEU D C   1 
ATOM   561  O  O   . LEU A 1 97  ? -0.51476  -23.36557 47.46580  1.000 30.44626  ? 77  LEU D O   1 
ATOM   562  C  CB  . LEU A 1 97  ? 1.08779   -25.87386 47.24965  1.000 23.61976  ? 77  LEU D CB  1 
ATOM   563  C  CG  . LEU A 1 97  ? 0.30895   -26.86872 48.10781  1.000 28.28899  ? 77  LEU D CG  1 
ATOM   564  C  CD1 . LEU A 1 97  ? -0.15080  -28.04277 47.26892  1.000 28.10324  ? 77  LEU D CD1 1 
ATOM   565  C  CD2 . LEU A 1 97  ? 1.15779   -27.34170 49.27642  1.000 26.33818  ? 77  LEU D CD2 1 
ATOM   566  N  N   . THR A 1 98  ? -2.01810  -24.57848 46.29721  1.000 30.91781  ? 78  THR D N   1 
ATOM   567  C  CA  . THR A 1 98  ? -3.14457  -23.74960 46.70706  1.000 33.29507  ? 78  THR D CA  1 
ATOM   568  C  C   . THR A 1 98  ? -4.28112  -24.60897 47.24616  1.000 33.79625  ? 78  THR D C   1 
ATOM   569  O  O   . THR A 1 98  ? -4.35469  -25.81346 47.00152  1.000 36.28238  ? 78  THR D O   1 
ATOM   570  C  CB  . THR A 1 98  ? -3.66263  -22.87109 45.55270  1.000 27.38488  ? 78  THR D CB  1 
ATOM   571  O  OG1 . THR A 1 98  ? -4.03579  -23.69631 44.44109  1.000 27.34553  ? 78  THR D OG1 1 
ATOM   572  C  CG2 . THR A 1 98  ? -2.59324  -21.87917 45.11004  1.000 24.60599  ? 78  THR D CG2 1 
ATOM   573  N  N   . TRP A 1 99  ? -5.16845  -23.96633 48.00780  1.000 35.22699  ? 79  TRP D N   1 
ATOM   574  C  CA  . TRP A 1 99  ? -6.39191  -24.62537 48.44965  1.000 27.98795  ? 79  TRP D CA  1 
ATOM   575  C  C   . TRP A 1 99  ? -7.49789  -24.52697 47.40739  1.000 34.94787  ? 79  TRP D C   1 
ATOM   576  O  O   . TRP A 1 99  ? -8.38047  -25.39202 47.36666  1.000 35.17352  ? 79  TRP D O   1 
ATOM   577  C  CB  . TRP A 1 99  ? -6.87626  -24.02884 49.77456  1.000 31.17162  ? 79  TRP D CB  1 
ATOM   578  C  CG  . TRP A 1 99  ? -6.10359  -24.45139 50.99254  1.000 32.18465  ? 79  TRP D CG  1 
ATOM   579  C  CD1 . TRP A 1 99  ? -5.16272  -23.72195 51.66021  1.000 28.67401  ? 79  TRP D CD1 1 
ATOM   580  C  CD2 . TRP A 1 99  ? -6.21898  -25.69632 51.69499  1.000 30.09365  ? 79  TRP D CD2 1 
ATOM   581  N  NE1 . TRP A 1 99  ? -4.68183  -24.43737 52.73123  1.000 31.65742  ? 79  TRP D NE1 1 
ATOM   582  C  CE2 . TRP A 1 99  ? -5.31477  -25.65182 52.77534  1.000 24.49377  ? 79  TRP D CE2 1 
ATOM   583  C  CE3 . TRP A 1 99  ? -6.99557  -26.84577 51.51168  1.000 31.13882  ? 79  TRP D CE3 1 
ATOM   584  C  CZ2 . TRP A 1 99  ? -5.16820  -26.71049 53.66998  1.000 32.93228  ? 79  TRP D CZ2 1 
ATOM   585  C  CZ3 . TRP A 1 99  ? -6.85244  -27.89210 52.40331  1.000 25.91186  ? 79  TRP D CZ3 1 
ATOM   586  C  CH2 . TRP A 1 99  ? -5.94401  -27.81868 53.46689  1.000 31.98176  ? 79  TRP D CH2 1 
ATOM   587  N  N   . ASP A 1 100 ? -7.47827  -23.47176 46.56961  1.000 32.22835  ? 80  ASP D N   1 
ATOM   588  C  CA  . ASP A 1 100 ? -8.47141  -23.29093 45.52542  1.000 37.91449  ? 80  ASP D CA  1 
ATOM   589  C  C   . ASP A 1 100 ? -7.96899  -23.84999 44.19840  1.000 37.28713  ? 80  ASP D C   1 
ATOM   590  O  O   . ASP A 1 100 ? -6.76847  -23.80791 43.91347  1.000 37.28898  ? 80  ASP D O   1 
ATOM   591  C  CB  . ASP A 1 100 ? -8.82497  -21.80925 45.35190  1.000 40.58573  ? 80  ASP D CB  1 
ATOM   592  C  CG  . ASP A 1 100 ? -7.59877  -20.91056 45.29700  1.000 53.04764  ? 80  ASP D CG  1 
ATOM   593  O  OD1 . ASP A 1 100 ? -6.79470  -20.92683 46.25674  1.000 46.21392  ? 80  ASP D OD1 1 
ATOM   594  O  OD2 . ASP A 1 100 ? -7.43967  -20.18496 44.29157  1.000 48.58140  ? 80  ASP D OD2 1 
ATOM   595  N  N   . PRO A 1 101 ? -8.86296  -24.39035 43.37364  1.000 43.04248  ? 81  PRO D N   1 
ATOM   596  C  CA  . PRO A 1 101 ? -8.44282  -24.97632 42.09778  1.000 39.03322  ? 81  PRO D CA  1 
ATOM   597  C  C   . PRO A 1 101 ? -7.95399  -23.90532 41.14218  1.000 42.33421  ? 81  PRO D C   1 
ATOM   598  O  O   . PRO A 1 101 ? -8.64925  -22.90746 40.89786  1.000 39.38572  ? 81  PRO D O   1 
ATOM   599  C  CB  . PRO A 1 101 ? -9.72372  -25.64739 41.57166  1.000 34.91155  ? 81  PRO D CB  1 
ATOM   600  C  CG  . PRO A 1 101 ? -10.63133 -25.74973 42.75616  1.000 40.68126  ? 81  PRO D CG  1 
ATOM   601  C  CD  . PRO A 1 101 ? -10.30221 -24.57498 43.61487  1.000 44.01875  ? 81  PRO D CD  1 
ATOM   602  N  N   . PRO A 1 102 ? -6.75606  -24.07433 40.58429  1.000 47.61640  ? 82  PRO D N   1 
ATOM   603  C  CA  . PRO A 1 102 ? -6.27091  -23.17423 39.53008  1.000 36.89100  ? 82  PRO D CA  1 
ATOM   604  C  C   . PRO A 1 102 ? -6.74471  -23.52968 38.12753  1.000 38.27199  ? 82  PRO D C   1 
ATOM   605  O  O   . PRO A 1 102 ? -6.31001  -22.88332 37.16982  1.000 38.83264  ? 82  PRO D O   1 
ATOM   606  C  CB  . PRO A 1 102 ? -4.75147  -23.34886 39.63882  1.000 39.10106  ? 82  PRO D CB  1 
ATOM   607  C  CG  . PRO A 1 102 ? -4.59170  -24.78259 40.02029  1.000 36.72487  ? 82  PRO D CG  1 
ATOM   608  C  CD  . PRO A 1 102 ? -5.76214  -25.10683 40.92535  1.000 37.32545  ? 82  PRO D CD  1 
ATOM   609  N  N   . PHE A 1 103 ? -7.60415  -24.53597 37.98345  1.000 36.23383  ? 83  PHE D N   1 
ATOM   610  C  CA  . PHE A 1 103 ? -8.16083  -24.91824 36.69522  1.000 47.73560  ? 83  PHE D CA  1 
ATOM   611  C  C   . PHE A 1 103 ? -9.64151  -25.22161 36.88346  1.000 39.20255  ? 83  PHE D C   1 
ATOM   612  O  O   . PHE A 1 103 ? -10.11633 -25.42008 38.00511  1.000 34.63600  ? 83  PHE D O   1 
ATOM   613  C  CB  . PHE A 1 103 ? -7.41503  -26.12134 36.09992  1.000 46.95788  ? 83  PHE D CB  1 
ATOM   614  C  CG  . PHE A 1 103 ? -7.17055  -27.22987 37.08117  1.000 43.10994  ? 83  PHE D CG  1 
ATOM   615  C  CD1 . PHE A 1 103 ? -8.16001  -28.15657 37.35918  1.000 40.90807  ? 83  PHE D CD1 1 
ATOM   616  C  CD2 . PHE A 1 103 ? -5.95228  -27.34090 37.72976  1.000 41.46687  ? 83  PHE D CD2 1 
ATOM   617  C  CE1 . PHE A 1 103 ? -7.94280  -29.16993 38.26698  1.000 45.50857  ? 83  PHE D CE1 1 
ATOM   618  C  CE2 . PHE A 1 103 ? -5.72750  -28.35732 38.63972  1.000 37.61302  ? 83  PHE D CE2 1 
ATOM   619  C  CZ  . PHE A 1 103 ? -6.72508  -29.27234 38.90775  1.000 40.89810  ? 83  PHE D CZ  1 
ATOM   620  N  N   . ALA A 1 104 ? -10.37694 -25.26691 35.77182  1.000 35.48664  ? 84  ALA D N   1 
ATOM   621  C  CA  . ALA A 1 104 ? -11.81569 -25.52855 35.82083  1.000 50.05291  ? 84  ALA D CA  1 
ATOM   622  C  C   . ALA A 1 104 ? -12.16608 -26.94896 35.37588  1.000 57.60364  ? 84  ALA D C   1 
ATOM   623  O  O   . ALA A 1 104 ? -12.90190 -27.13969 34.40492  1.000 68.69459  ? 84  ALA D O   1 
ATOM   624  C  CB  . ALA A 1 104 ? -12.57336 -24.50593 34.96013  1.000 49.60317  ? 84  ALA D CB  1 
ATOM   625  N  N   . ALA A 1 105 ? -11.68147 -27.95325 36.09838  1.000 54.52619  ? 85  ALA D N   1 
ATOM   626  C  CA  . ALA A 1 105 ? -11.97827 -29.33246 35.74384  1.000 48.40989  ? 85  ALA D CA  1 
ATOM   627  C  C   . ALA A 1 105 ? -13.36427 -29.73921 36.23729  1.000 62.10140  ? 85  ALA D C   1 
ATOM   628  O  O   . ALA A 1 105 ? -13.89875 -29.18557 37.20129  1.000 57.78447  ? 85  ALA D O   1 
ATOM   629  C  CB  . ALA A 1 105 ? -10.92584 -30.27831 36.32840  1.000 51.95173  ? 85  ALA D CB  1 
ATOM   630  N  N   . ASP A 1 106 ? -13.92570 -30.75637 35.57654  1.000 64.90856  ? 86  ASP D N   1 
ATOM   631  C  CA  . ASP A 1 106 ? -15.27439 -31.22551 35.88131  1.000 62.65468  ? 86  ASP D CA  1 
ATOM   632  C  C   . ASP A 1 106 ? -15.42638 -31.69264 37.32644  1.000 73.63536  ? 86  ASP D C   1 
ATOM   633  O  O   . ASP A 1 106 ? -16.55915 -31.82991 37.80259  1.000 64.71602  ? 86  ASP D O   1 
ATOM   634  C  CB  . ASP A 1 106 ? -15.64510 -32.35916 34.91787  1.000 70.62846  ? 86  ASP D CB  1 
ATOM   635  C  CG  . ASP A 1 106 ? -17.14713 -32.49973 34.71559  1.000 70.50382  ? 86  ASP D CG  1 
ATOM   636  O  OD1 . ASP A 1 106 ? -17.88374 -32.66756 35.71027  1.000 74.78517  ? 86  ASP D OD1 1 
ATOM   637  O  OD2 . ASP A 1 106 ? -17.59228 -32.44832 33.54961  1.000 71.17285  ? 86  ASP D OD2 1 
ATOM   638  N  N   . GLU A 1 107 ? -14.31565 -31.95051 38.02488  1.000 74.62924  ? 87  GLU D N   1 
ATOM   639  C  CA  . GLU A 1 107 ? -14.29051 -32.50321 39.37968  1.000 69.33175  ? 87  GLU D CA  1 
ATOM   640  C  C   . GLU A 1 107 ? -14.79025 -33.94496 39.39802  1.000 71.27748  ? 87  GLU D C   1 
ATOM   641  O  O   . GLU A 1 107 ? -14.41300 -34.72294 40.28071  1.000 60.71585  ? 87  GLU D O   1 
ATOM   642  C  CB  . GLU A 1 107 ? -15.08830 -31.63152 40.35450  1.000 73.24424  ? 87  GLU D CB  1 
ATOM   643  C  CG  . GLU A 1 107 ? -14.36406 -30.35766 40.76974  1.000 84.39911  ? 87  GLU D CG  1 
ATOM   644  C  CD  . GLU A 1 107 ? -15.09943 -29.10008 40.35034  1.000 87.00040  ? 87  GLU D CD  1 
ATOM   645  O  OE1 . GLU A 1 107 ? -16.16422 -29.21963 39.70807  1.000 79.30281  ? 87  GLU D OE1 1 
ATOM   646  O  OE2 . GLU A 1 107 ? -14.61275 -27.99256 40.66496  1.000 78.46010  ? 87  GLU D OE2 1 
ATOM   647  N  N   . GLY A 1 108 ? -15.64049 -34.31023 38.43725  1.000 72.11440  ? 88  GLY D N   1 
ATOM   648  C  CA  . GLY A 1 108 ? -15.83984 -35.70910 38.11392  1.000 51.23579  ? 88  GLY D CA  1 
ATOM   649  C  C   . GLY A 1 108 ? -14.63444 -36.36067 37.47228  1.000 59.64273  ? 88  GLY D C   1 
ATOM   650  O  O   . GLY A 1 108 ? -14.60212 -37.59034 37.35087  1.000 62.93401  ? 88  GLY D O   1 
ATOM   651  N  N   . ALA A 1 109 ? -13.65111 -35.56210 37.05749  1.000 69.27350  ? 89  ALA D N   1 
ATOM   652  C  CA  . ALA A 1 109 ? -12.36438 -36.04685 36.57977  1.000 61.35134  ? 89  ALA D CA  1 
ATOM   653  C  C   . ALA A 1 109 ? -11.38437 -36.32982 37.71452  1.000 57.93405  ? 89  ALA D C   1 
ATOM   654  O  O   . ALA A 1 109 ? -10.20125 -36.56571 37.44733  1.000 59.39394  ? 89  ALA D O   1 
ATOM   655  C  CB  . ALA A 1 109 ? -11.75278 -35.03690 35.60391  1.000 63.45905  ? 89  ALA D CB  1 
ATOM   656  N  N   . PHE A 1 110 ? -11.84313 -36.29914 38.96262  1.000 54.99994  ? 90  PHE D N   1 
ATOM   657  C  CA  . PHE A 1 110 ? -11.04703 -36.65329 40.12556  1.000 52.36858  ? 90  PHE D CA  1 
ATOM   658  C  C   . PHE A 1 110 ? -11.81450 -37.63825 40.99287  1.000 50.93425  ? 90  PHE D C   1 
ATOM   659  O  O   . PHE A 1 110 ? -13.05011 -37.64381 40.98827  1.000 50.54052  ? 90  PHE D O   1 
ATOM   660  C  CB  . PHE A 1 110 ? -10.69404 -35.42091 40.97268  1.000 47.90909  ? 90  PHE D CB  1 
ATOM   661  C  CG  . PHE A 1 110 ? -9.88388  -34.39005 40.24711  1.000 43.74661  ? 90  PHE D CG  1 
ATOM   662  C  CD1 . PHE A 1 110 ? -8.55852  -34.63084 39.92796  1.000 41.03896  ? 90  PHE D CD1 1 
ATOM   663  C  CD2 . PHE A 1 110 ? -10.44158 -33.16941 39.90237  1.000 42.75218  ? 90  PHE D CD2 1 
ATOM   664  C  CE1 . PHE A 1 110 ? -7.80791  -33.68079 39.26531  1.000 35.12081  ? 90  PHE D CE1 1 
ATOM   665  C  CE2 . PHE A 1 110 ? -9.69792  -32.21418 39.24098  1.000 34.61990  ? 90  PHE D CE2 1 
ATOM   666  C  CZ  . PHE A 1 110 ? -8.37804  -32.47034 38.92153  1.000 51.37148  ? 90  PHE D CZ  1 
ATOM   667  N  N   . PRO A 1 111 ? -11.11139 -38.49131 41.73357  1.000 51.43818  ? 91  PRO D N   1 
ATOM   668  C  CA  . PRO A 1 111 ? -11.76247 -39.26584 42.79037  1.000 52.04508  ? 91  PRO D CA  1 
ATOM   669  C  C   . PRO A 1 111 ? -12.27477 -38.33995 43.87707  1.000 54.63846  ? 91  PRO D C   1 
ATOM   670  O  O   . PRO A 1 111 ? -11.80411 -37.19960 44.00355  1.000 55.45232  ? 91  PRO D O   1 
ATOM   671  C  CB  . PRO A 1 111 ? -10.64085 -40.17241 43.31922  1.000 46.40281  ? 91  PRO D CB  1 
ATOM   672  C  CG  . PRO A 1 111 ? -9.65779  -40.24598 42.19042  1.000 54.31118  ? 91  PRO D CG  1 
ATOM   673  C  CD  . PRO A 1 111 ? -9.71683  -38.90581 41.52176  1.000 49.22844  ? 91  PRO D CD  1 
ATOM   674  N  N   . PRO A 1 112 ? -13.25342 -38.77426 44.67319  1.000 60.70805  ? 92  PRO D N   1 
ATOM   675  C  CA  . PRO A 1 112 ? -13.79124 -37.88700 45.71756  1.000 54.53831  ? 92  PRO D CA  1 
ATOM   676  C  C   . PRO A 1 112 ? -12.74403 -37.57395 46.77845  1.000 48.13535  ? 92  PRO D C   1 
ATOM   677  O  O   . PRO A 1 112 ? -11.91813 -38.41816 47.13377  1.000 43.80835  ? 92  PRO D O   1 
ATOM   678  C  CB  . PRO A 1 112 ? -14.96064 -38.69207 46.30732  1.000 52.62374  ? 92  PRO D CB  1 
ATOM   679  C  CG  . PRO A 1 112 ? -14.59414 -40.11163 46.03519  1.000 58.33112  ? 92  PRO D CG  1 
ATOM   680  C  CD  . PRO A 1 112 ? -13.90050 -40.09846 44.70284  1.000 59.58249  ? 92  PRO D CD  1 
ATOM   681  N  N   . ALA A 1 113 ? -12.77431 -36.33743 47.26617  1.000 47.00434  ? 93  ALA D N   1 
ATOM   682  C  CA  . ALA A 1 113 ? -11.84189 -35.88458 48.28563  1.000 39.26484  ? 93  ALA D CA  1 
ATOM   683  C  C   . ALA A 1 113 ? -12.48242 -34.74687 49.06601  1.000 38.79222  ? 93  ALA D C   1 
ATOM   684  O  O   . ALA A 1 113 ? -13.12821 -33.87525 48.47975  1.000 35.18242  ? 93  ALA D O   1 
ATOM   685  C  CB  . ALA A 1 113 ? -10.51208 -35.43055 47.66687  1.000 37.37859  ? 93  ALA D CB  1 
ATOM   686  N  N   . GLU A 1 114 ? -12.30025 -34.75869 50.38789  1.000 41.51125  ? 94  GLU D N   1 
ATOM   687  C  CA  . GLU A 1 114 ? -12.92649 -33.75144 51.23704  1.000 51.78120  ? 94  GLU D CA  1 
ATOM   688  C  C   . GLU A 1 114 ? -12.08912 -32.48731 51.36898  1.000 41.87992  ? 94  GLU D C   1 
ATOM   689  O  O   . GLU A 1 114 ? -12.64511 -31.38524 51.42217  1.000 45.72757  ? 94  GLU D O   1 
ATOM   690  C  CB  . GLU A 1 114 ? -13.21238 -34.32761 52.62577  1.000 52.89138  ? 94  GLU D CB  1 
ATOM   691  C  CG  . GLU A 1 114 ? -14.30656 -35.37457 52.63281  1.000 51.61646  ? 94  GLU D CG  1 
ATOM   692  C  CD  . GLU A 1 114 ? -14.82613 -35.67469 54.02187  1.000 63.41006  ? 94  GLU D CD  1 
ATOM   693  O  OE1 . GLU A 1 114 ? -14.04173 -35.58659 54.99028  1.000 66.18311  ? 94  GLU D OE1 1 
ATOM   694  O  OE2 . GLU A 1 114 ? -16.02742 -35.99223 54.14083  1.000 72.29246  ? 94  GLU D OE2 1 
ATOM   695  N  N   . ARG A 1 115 ? -10.76609 -32.61806 51.43458  1.000 46.26158  ? 95  ARG D N   1 
ATOM   696  C  CA  . ARG A 1 115 ? -9.86031  -31.47629 51.56503  1.000 39.70185  ? 95  ARG D CA  1 
ATOM   697  C  C   . ARG A 1 115 ? -8.72477  -31.60786 50.55682  1.000 40.56398  ? 95  ARG D C   1 
ATOM   698  O  O   . ARG A 1 115 ? -7.58796  -31.93571 50.91878  1.000 38.24718  ? 95  ARG D O   1 
ATOM   699  C  CB  . ARG A 1 115 ? -9.31043  -31.37461 52.98772  1.000 40.75339  ? 95  ARG D CB  1 
ATOM   700  C  CG  . ARG A 1 115 ? -10.37179 -31.34789 54.07144  1.000 44.14870  ? 95  ARG D CG  1 
ATOM   701  C  CD  . ARG A 1 115 ? -9.74188  -31.46120 55.44520  1.000 43.79011  ? 95  ARG D CD  1 
ATOM   702  N  NE  . ARG A 1 115 ? -8.85557  -32.61396 55.54682  1.000 58.07899  ? 95  ARG D NE  1 
ATOM   703  C  CZ  . ARG A 1 115 ? -9.25691  -33.84615 55.82657  1.000 52.88198  ? 95  ARG D CZ  1 
ATOM   704  N  NH1 . ARG A 1 115 ? -10.53216 -34.12613 56.04092  1.000 61.32906  ? 95  ARG D NH1 1 
ATOM   705  N  NH2 . ARG A 1 115 ? -8.35641  -34.82261 55.89014  1.000 52.24293  ? 95  ARG D NH2 1 
ATOM   706  N  N   . PRO A 1 116 ? -8.99536  -31.35026 49.27840  1.000 36.73224  ? 96  PRO D N   1 
ATOM   707  C  CA  . PRO A 1 116 ? -7.93139  -31.43986 48.27392  1.000 34.23139  ? 96  PRO D CA  1 
ATOM   708  C  C   . PRO A 1 116 ? -7.12665  -30.15300 48.18126  1.000 35.00612  ? 96  PRO D C   1 
ATOM   709  O  O   . PRO A 1 116 ? -7.66773  -29.04659 48.25320  1.000 37.27852  ? 96  PRO D O   1 
ATOM   710  C  CB  . PRO A 1 116 ? -8.70246  -31.69835 46.97512  1.000 34.74354  ? 96  PRO D CB  1 
ATOM   711  C  CG  . PRO A 1 116 ? -9.99247  -30.97227 47.18429  1.000 32.50737  ? 96  PRO D CG  1 
ATOM   712  C  CD  . PRO A 1 116 ? -10.30512 -31.06153 48.66550  1.000 32.61628  ? 96  PRO D CD  1 
ATOM   713  N  N   . LEU A 1 117 ? -5.81536  -30.30704 48.03398  1.000 30.32853  ? 97  LEU D N   1 
ATOM   714  C  CA  . LEU A 1 117 ? -4.94893  -29.20747 47.64227  1.000 32.20920  ? 97  LEU D CA  1 
ATOM   715  C  C   . LEU A 1 117 ? -4.55920  -29.38452 46.18286  1.000 37.39954  ? 97  LEU D C   1 
ATOM   716  O  O   . LEU A 1 117 ? -4.65508  -30.47815 45.61828  1.000 32.81888  ? 97  LEU D O   1 
ATOM   717  C  CB  . LEU A 1 117 ? -3.69800  -29.11548 48.52287  1.000 31.90962  ? 97  LEU D CB  1 
ATOM   718  C  CG  . LEU A 1 117 ? -3.90496  -28.48234 49.90046  1.000 34.05899  ? 97  LEU D CG  1 
ATOM   719  C  CD1 . LEU A 1 117 ? -4.19156  -29.55117 50.92962  1.000 39.73158  ? 97  LEU D CD1 1 
ATOM   720  C  CD2 . LEU A 1 117 ? -2.70300  -27.64444 50.31013  1.000 28.10300  ? 97  LEU D CD2 1 
ATOM   721  N  N   . TYR A 1 118 ? -4.12323  -28.29271 45.56783  1.000 30.41066  ? 98  TYR D N   1 
ATOM   722  C  CA  . TYR A 1 118 ? -3.90460  -28.26010 44.13344  1.000 32.62595  ? 98  TYR D CA  1 
ATOM   723  C  C   . TYR A 1 118 ? -2.47421  -27.84466 43.83746  1.000 30.51777  ? 98  TYR D C   1 
ATOM   724  O  O   . TYR A 1 118 ? -1.98909  -26.83014 44.35851  1.000 24.13934  ? 98  TYR D O   1 
ATOM   725  C  CB  . TYR A 1 118 ? -4.89990  -27.31742 43.45947  1.000 35.24579  ? 98  TYR D CB  1 
ATOM   726  C  CG  . TYR A 1 118 ? -6.33017  -27.79812 43.55992  1.000 37.35244  ? 98  TYR D CG  1 
ATOM   727  C  CD1 . TYR A 1 118 ? -7.11608  -27.47846 44.66136  1.000 36.46750  ? 98  TYR D CD1 1 
ATOM   728  C  CD2 . TYR A 1 118 ? -6.89091  -28.58040 42.56025  1.000 34.54880  ? 98  TYR D CD2 1 
ATOM   729  C  CE1 . TYR A 1 118 ? -8.42103  -27.91955 44.75912  1.000 34.10780  ? 98  TYR D CE1 1 
ATOM   730  C  CE2 . TYR A 1 118 ? -8.19492  -29.02386 42.64771  1.000 36.24072  ? 98  TYR D CE2 1 
ATOM   731  C  CZ  . TYR A 1 118 ? -8.95511  -28.69109 43.74776  1.000 36.43016  ? 98  TYR D CZ  1 
ATOM   732  O  OH  . TYR A 1 118 ? -10.25386 -29.13523 43.83355  1.000 36.86069  ? 98  TYR D OH  1 
ATOM   733  N  N   . LEU A 1 119 ? -1.81354  -28.64650 43.00934  1.000 31.21944  ? 99  LEU D N   1 
ATOM   734  C  CA  . LEU A 1 119 ? -0.45561  -28.40569 42.55229  1.000 30.41213  ? 99  LEU D CA  1 
ATOM   735  C  C   . LEU A 1 119 ? -0.50601  -27.81836 41.15022  1.000 32.10974  ? 99  LEU D C   1 
ATOM   736  O  O   . LEU A 1 119 ? -1.15561  -28.37810 40.25995  1.000 28.83879  ? 99  LEU D O   1 
ATOM   737  C  CB  . LEU A 1 119 ? 0.35130   -29.70540 42.55267  1.000 25.80283  ? 99  LEU D CB  1 
ATOM   738  C  CG  . LEU A 1 119 ? 1.70513   -29.68354 41.84207  1.000 33.12245  ? 99  LEU D CG  1 
ATOM   739  C  CD1 . LEU A 1 119 ? 2.74865   -29.00083 42.70229  1.000 24.12657  ? 99  LEU D CD1 1 
ATOM   740  C  CD2 . LEU A 1 119 ? 2.14697   -31.09322 41.46438  1.000 27.76408  ? 99  LEU D CD2 1 
ATOM   741  N  N   . SER A 1 120 ? 0.16972   -26.69005 40.95999  1.000 24.47019  ? 100 SER D N   1 
ATOM   742  C  CA  . SER A 1 120 ? 0.23815   -26.05189 39.65769  1.000 22.98325  ? 100 SER D CA  1 
ATOM   743  C  C   . SER A 1 120 ? 1.62962   -25.47400 39.45711  1.000 28.99577  ? 100 SER D C   1 
ATOM   744  O  O   . SER A 1 120 ? 2.42257   -25.35326 40.39700  1.000 27.91856  ? 100 SER D O   1 
ATOM   745  C  CB  . SER A 1 120 ? -0.82214  -24.95037 39.50340  1.000 21.35863  ? 100 SER D CB  1 
ATOM   746  O  OG  . SER A 1 120 ? -0.66141  -23.94759 40.48970  1.000 25.75860  ? 100 SER D OG  1 
ATOM   747  N  N   . ARG A 1 121 ? 1.92245   -25.14810 38.19996  1.000 24.30811  ? 101 ARG D N   1 
ATOM   748  C  CA  . ARG A 1 121 ? 3.13576   -24.42194 37.83435  1.000 25.23963  ? 101 ARG D CA  1 
ATOM   749  C  C   . ARG A 1 121 ? 4.39468   -25.10686 38.36145  1.000 24.28188  ? 101 ARG D C   1 
ATOM   750  O  O   . ARG A 1 121 ? 5.31597   -24.45809 38.86177  1.000 22.99440  ? 101 ARG D O   1 
ATOM   751  C  CB  . ARG A 1 121 ? 3.06248   -22.97627 38.31877  1.000 18.32742  ? 101 ARG D CB  1 
ATOM   752  C  CG  . ARG A 1 121 ? 1.97038   -22.16749 37.65070  1.000 26.31644  ? 101 ARG D CG  1 
ATOM   753  C  CD  . ARG A 1 121 ? 2.03811   -20.71468 38.08120  1.000 39.36150  ? 101 ARG D CD  1 
ATOM   754  N  NE  . ARG A 1 121 ? 1.58813   -19.81494 37.02797  1.000 36.55996  ? 101 ARG D NE  1 
ATOM   755  C  CZ  . ARG A 1 121 ? 2.02205   -18.57153 36.88593  1.000 31.02989  ? 101 ARG D CZ  1 
ATOM   756  N  NH1 . ARG A 1 121 ? 2.91854   -18.05787 37.71099  1.000 33.93372  ? 101 ARG D NH1 1 
ATOM   757  N  NH2 . ARG A 1 121 ? 1.55847   -17.83152 35.88253  1.000 42.20924  ? 101 ARG D NH2 1 
ATOM   758  N  N   . LEU A 1 122 ? 4.43119   -26.43377 38.26354  1.000 26.33121  ? 102 LEU D N   1 
ATOM   759  C  CA  . LEU A 1 122 ? 5.66479   -27.15644 38.54212  1.000 24.44698  ? 102 LEU D CA  1 
ATOM   760  C  C   . LEU A 1 122 ? 6.71001   -26.78545 37.49798  1.000 22.36370  ? 102 LEU D C   1 
ATOM   761  O  O   . LEU A 1 122 ? 6.45297   -26.86724 36.29359  1.000 31.07865  ? 102 LEU D O   1 
ATOM   762  C  CB  . LEU A 1 122 ? 5.42175   -28.66313 38.53817  1.000 26.08894  ? 102 LEU D CB  1 
ATOM   763  C  CG  . LEU A 1 122 ? 6.63304   -29.53471 38.89070  1.000 30.30242  ? 102 LEU D CG  1 
ATOM   764  C  CD1 . LEU A 1 122 ? 6.90038   -29.53191 40.39202  1.000 33.66518  ? 102 LEU D CD1 1 
ATOM   765  C  CD2 . LEU A 1 122 ? 6.43752   -30.94726 38.37561  1.000 24.37781  ? 102 LEU D CD2 1 
ATOM   766  N  N   . ALA A 1 123 ? 7.88368   -26.35624 37.95459  1.000 25.52091  ? 103 ALA D N   1 
ATOM   767  C  CA  . ALA A 1 123 ? 8.91106   -25.88695 37.03546  1.000 32.38201  ? 103 ALA D CA  1 
ATOM   768  C  C   . ALA A 1 123 ? 10.28937  -26.25792 37.56009  1.000 35.39031  ? 103 ALA D C   1 
ATOM   769  O  O   . ALA A 1 123 ? 10.58577  -26.06453 38.74321  1.000 29.60598  ? 103 ALA D O   1 
ATOM   770  C  CB  . ALA A 1 123 ? 8.81357   -24.37137 36.82926  1.000 36.34043  ? 103 ALA D CB  1 
ATOM   771  N  N   . VAL A 1 124 ? 11.12466  -26.78761 36.67204  1.000 32.99764  ? 104 VAL D N   1 
ATOM   772  C  CA  . VAL A 1 124 ? 12.51380  -27.11563 36.96889  1.000 34.60417  ? 104 VAL D CA  1 
ATOM   773  C  C   . VAL A 1 124 ? 13.39260  -26.32467 36.01019  1.000 33.57849  ? 104 VAL D C   1 
ATOM   774  O  O   . VAL A 1 124 ? 13.12531  -26.29295 34.80279  1.000 36.40227  ? 104 VAL D O   1 
ATOM   775  C  CB  . VAL A 1 124 ? 12.78340  -28.62717 36.84060  1.000 31.22051  ? 104 VAL D CB  1 
ATOM   776  C  CG1 . VAL A 1 124 ? 14.21425  -28.95714 37.25020  1.000 34.83794  ? 104 VAL D CG1 1 
ATOM   777  C  CG2 . VAL A 1 124 ? 11.79007  -29.41491 37.67638  1.000 25.08266  ? 104 VAL D CG2 1 
ATOM   778  N  N   . ALA A 1 125 ? 14.43038  -25.68691 36.54567  1.000 30.63629  ? 105 ALA D N   1 
ATOM   779  C  CA  . ALA A 1 125 ? 15.32353  -24.89702 35.71080  1.000 35.60949  ? 105 ALA D CA  1 
ATOM   780  C  C   . ALA A 1 125 ? 15.91144  -25.77153 34.60632  1.000 32.53746  ? 105 ALA D C   1 
ATOM   781  O  O   . ALA A 1 125 ? 16.26265  -26.93091 34.85610  1.000 40.50523  ? 105 ALA D O   1 
ATOM   782  C  CB  . ALA A 1 125 ? 16.44684  -24.28149 36.54768  1.000 34.79385  ? 105 ALA D CB  1 
ATOM   783  N  N   . PRO A 1 126 ? 16.01924  -25.25655 33.37964  1.000 25.01524  ? 106 PRO D N   1 
ATOM   784  C  CA  . PRO A 1 126 ? 16.51660  -26.08326 32.26478  1.000 38.14361  ? 106 PRO D CA  1 
ATOM   785  C  C   . PRO A 1 126 ? 17.83992  -26.78551 32.53467  1.000 35.57694  ? 106 PRO D C   1 
ATOM   786  O  O   . PRO A 1 126 ? 18.02134  -27.92688 32.08821  1.000 40.21501  ? 106 PRO D O   1 
ATOM   787  C  CB  . PRO A 1 126 ? 16.63546  -25.06902 31.11977  1.000 32.28202  ? 106 PRO D CB  1 
ATOM   788  C  CG  . PRO A 1 126 ? 15.58384  -24.04911 31.42372  1.000 39.56534  ? 106 PRO D CG  1 
ATOM   789  C  CD  . PRO A 1 126 ? 15.51750  -23.94764 32.92594  1.000 30.55588  ? 106 PRO D CD  1 
ATOM   790  N  N   . GLU A 1 127 ? 18.76151  -26.15628 33.26748  1.000 34.58421  ? 107 GLU D N   1 
ATOM   791  C  CA  . GLU A 1 127 ? 20.03238  -26.80605 33.56248  1.000 41.16700  ? 107 GLU D CA  1 
ATOM   792  C  C   . GLU A 1 127 ? 19.89170  -27.99057 34.51322  1.000 41.57493  ? 107 GLU D C   1 
ATOM   793  O  O   . GLU A 1 127 ? 20.82904  -28.78826 34.61422  1.000 42.90211  ? 107 GLU D O   1 
ATOM   794  C  CB  . GLU A 1 127 ? 21.02497  -25.79334 34.14006  1.000 41.14851  ? 107 GLU D CB  1 
ATOM   795  C  CG  . GLU A 1 127 ? 20.56413  -25.09980 35.41228  1.000 48.76254  ? 107 GLU D CG  1 
ATOM   796  C  CD  . GLU A 1 127 ? 19.92690  -23.74756 35.14966  1.000 56.26061  ? 107 GLU D CD  1 
ATOM   797  O  OE1 . GLU A 1 127 ? 19.20263  -23.60519 34.13952  1.000 39.65471  ? 107 GLU D OE1 1 
ATOM   798  O  OE2 . GLU A 1 127 ? 20.15940  -22.82154 35.95578  1.000 54.24114  ? 107 GLU D OE2 1 
ATOM   799  N  N   . TRP A 1 128 ? 18.75576  -28.13753 35.19570  1.000 37.71345  ? 108 TRP D N   1 
ATOM   800  C  CA  . TRP A 1 128 ? 18.50993  -29.28662 36.05846  1.000 39.52926  ? 108 TRP D CA  1 
ATOM   801  C  C   . TRP A 1 128 ? 17.59030  -30.31760 35.41992  1.000 41.13192  ? 108 TRP D C   1 
ATOM   802  O  O   . TRP A 1 128 ? 17.24247  -31.30460 36.07503  1.000 37.55545  ? 108 TRP D O   1 
ATOM   803  C  CB  . TRP A 1 128 ? 17.92149  -28.83821 37.40484  1.000 32.91212  ? 108 TRP D CB  1 
ATOM   804  C  CG  . TRP A 1 128 ? 18.84645  -27.98048 38.20869  1.000 38.57204  ? 108 TRP D CG  1 
ATOM   805  C  CD1 . TRP A 1 128 ? 18.75750  -26.63287 38.39431  1.000 36.28636  ? 108 TRP D CD1 1 
ATOM   806  C  CD2 . TRP A 1 128 ? 20.01000  -28.40905 38.92858  1.000 41.74670  ? 108 TRP D CD2 1 
ATOM   807  N  NE1 . TRP A 1 128 ? 19.79023  -26.19438 39.18667  1.000 43.20467  ? 108 TRP D NE1 1 
ATOM   808  C  CE2 . TRP A 1 128 ? 20.57410  -27.26520 39.52787  1.000 39.44169  ? 108 TRP D CE2 1 
ATOM   809  C  CE3 . TRP A 1 128 ? 20.62868  -29.64849 39.12496  1.000 38.11272  ? 108 TRP D CE3 1 
ATOM   810  C  CZ2 . TRP A 1 128 ? 21.72713  -27.32302 40.30996  1.000 36.52039  ? 108 TRP D CZ2 1 
ATOM   811  C  CZ3 . TRP A 1 128 ? 21.77314  -29.70351 39.90155  1.000 40.47235  ? 108 TRP D CZ3 1 
ATOM   812  C  CH2 . TRP A 1 128 ? 22.30951  -28.54791 40.48505  1.000 35.74033  ? 108 TRP D CH2 1 
ATOM   813  N  N   . LEU A 1 129 ? 17.19177  -30.11605 34.16436  1.000 41.88270  ? 109 LEU D N   1 
ATOM   814  C  CA  . LEU A 1 129 ? 16.33078  -31.05045 33.45212  1.000 41.33624  ? 109 LEU D CA  1 
ATOM   815  C  C   . LEU A 1 129 ? 17.10244  -32.19627 32.80868  1.000 46.27936  ? 109 LEU D C   1 
ATOM   816  O  O   . LEU A 1 129 ? 16.50688  -32.98849 32.07007  1.000 45.95548  ? 109 LEU D O   1 
ATOM   817  C  CB  . LEU A 1 129 ? 15.51710  -30.30053 32.39115  1.000 38.51886  ? 109 LEU D CB  1 
ATOM   818  C  CG  . LEU A 1 129 ? 14.37175  -29.44425 32.94115  1.000 40.97291  ? 109 LEU D CG  1 
ATOM   819  C  CD1 . LEU A 1 129 ? 13.65294  -28.67735 31.84244  1.000 39.16298  ? 109 LEU D CD1 1 
ATOM   820  C  CD2 . LEU A 1 129 ? 13.39513  -30.32401 33.69668  1.000 35.85308  ? 109 LEU D CD2 1 
ATOM   821  N  N   A THR A 1 130 ? 18.40810  -32.27154 33.04895  0.550 47.87484  ? 110 THR D N   1 
ATOM   822  N  N   B THR A 1 130 ? 18.39988  -32.33684 33.09088  0.450 48.78885  ? 110 THR D N   1 
ATOM   823  C  CA  A THR A 1 130 ? 19.23259  -33.39694 32.64627  0.550 53.49417  ? 110 THR D CA  1 
ATOM   824  C  CA  B THR A 1 130 ? 19.22396  -33.34090 32.41962  0.450 53.41001  ? 110 THR D CA  1 
ATOM   825  C  C   A THR A 1 130 ? 20.08159  -33.82543 33.83464  0.550 55.11535  ? 110 THR D C   1 
ATOM   826  C  C   B THR A 1 130 ? 19.73986  -34.39765 33.38921  0.450 56.90092  ? 110 THR D C   1 
ATOM   827  O  O   A THR A 1 130 ? 20.15862  -33.13638 34.85627  0.550 46.05507  ? 110 THR D O   1 
ATOM   828  O  O   B THR A 1 130 ? 19.28173  -35.54268 33.33710  0.450 55.41718  ? 110 THR D O   1 
ATOM   829  C  CB  A THR A 1 130 ? 20.12345  -33.05536 31.44290  0.550 51.27000  ? 110 THR D CB  1 
ATOM   830  C  CB  B THR A 1 130 ? 20.38060  -32.66149 31.68398  0.450 51.98014  ? 110 THR D CB  1 
ATOM   831  O  OG1 A THR A 1 130 ? 20.90970  -31.89360 31.73484  0.550 52.77372  ? 110 THR D OG1 1 
ATOM   832  O  OG1 B THR A 1 130 ? 19.85875  -31.74862 30.71126  0.450 54.99339  ? 110 THR D OG1 1 
ATOM   833  C  CG2 A THR A 1 130 ? 19.27421  -32.79607 30.20773  0.550 48.10679  ? 110 THR D CG2 1 
ATOM   834  C  CG2 B THR A 1 130 ? 21.25468  -33.69954 30.98753  0.450 52.97869  ? 110 THR D CG2 1 
ATOM   835  N  N   A GLY A 1 131 ? 20.71853  -34.98050 33.69427  0.550 57.97954  ? 111 GLY D N   1 
ATOM   836  N  N   B GLY A 1 131 ? 20.67774  -34.05716 34.26782  0.450 54.61569  ? 111 GLY D N   1 
ATOM   837  C  CA  A GLY A 1 131 ? 21.50348  -35.53274 34.77417  0.550 55.14754  ? 111 GLY D CA  1 
ATOM   838  C  CA  B GLY A 1 131 ? 21.40111  -35.04342 35.04089  0.450 54.73455  ? 111 GLY D CA  1 
ATOM   839  C  C   A GLY A 1 131 ? 20.64376  -36.22971 35.81257  0.550 56.70547  ? 111 GLY D C   1 
ATOM   840  C  C   B GLY A 1 131 ? 20.55547  -35.72580 36.10197  0.450 56.90622  ? 111 GLY D C   1 
ATOM   841  O  O   A GLY A 1 131 ? 19.46914  -36.54948 35.59770  0.550 56.72755  ? 111 GLY D O   1 
ATOM   842  O  O   B GLY A 1 131 ? 19.32960  -35.61602 36.15432  0.450 57.61738  ? 111 GLY D O   1 
ATOM   843  N  N   . GLY A 1 132 ? 21.25290  -36.45682 36.97202  1.000 55.70156  ? 112 GLY D N   1 
ATOM   844  C  CA  . GLY A 1 132 ? 20.59953  -37.20476 38.02751  1.000 56.35320  ? 112 GLY D CA  1 
ATOM   845  C  C   . GLY A 1 132 ? 20.55454  -36.50632 39.36842  1.000 59.73429  ? 112 GLY D C   1 
ATOM   846  O  O   . GLY A 1 132 ? 20.76344  -37.13957 40.40583  1.000 67.66690  ? 112 GLY D O   1 
ATOM   847  N  N   . SER A 1 133 ? 20.28609  -35.20172 39.36580  1.000 60.34269  ? 113 SER D N   1 
ATOM   848  C  CA  . SER A 1 133 ? 20.10093  -34.47226 40.61354  1.000 42.34935  ? 113 SER D CA  1 
ATOM   849  C  C   . SER A 1 133 ? 18.67486  -34.55933 41.13775  1.000 53.47155  ? 113 SER D C   1 
ATOM   850  O  O   . SER A 1 133 ? 18.43258  -34.16798 42.28540  1.000 46.08768  ? 113 SER D O   1 
ATOM   851  C  CB  . SER A 1 133 ? 20.50013  -33.00444 40.44139  1.000 48.41308  ? 113 SER D CB  1 
ATOM   852  O  OG  . SER A 1 133 ? 21.90322  -32.87960 40.28661  1.000 56.68769  ? 113 SER D OG  1 
ATOM   853  N  N   . LEU A 1 134 ? 17.73554  -35.04802 40.32338  1.000 48.41539  ? 114 LEU D N   1 
ATOM   854  C  CA  . LEU A 1 134 ? 16.38159  -35.37564 40.77202  1.000 45.58670  ? 114 LEU D CA  1 
ATOM   855  C  C   . LEU A 1 134 ? 15.65004  -34.15138 41.31997  1.000 39.34723  ? 114 LEU D C   1 
ATOM   856  O  O   . LEU A 1 134 ? 14.88801  -34.24606 42.28451  1.000 38.08730  ? 114 LEU D O   1 
ATOM   857  C  CB  . LEU A 1 134 ? 16.41299  -36.50117 41.80996  1.000 57.35096  ? 114 LEU D CB  1 
ATOM   858  C  CG  . LEU A 1 134 ? 17.17422  -37.77065 41.40969  1.000 52.35584  ? 114 LEU D CG  1 
ATOM   859  C  CD1 . LEU A 1 134 ? 17.17114  -38.78736 42.53955  1.000 48.70673  ? 114 LEU D CD1 1 
ATOM   860  C  CD2 . LEU A 1 134 ? 16.60349  -38.37912 40.13633  1.000 33.43161  ? 114 LEU D CD2 1 
ATOM   861  N  N   . VAL A 1 135 ? 15.87511  -32.99372 40.69256  1.000 34.18234  ? 115 VAL D N   1 
ATOM   862  C  CA  . VAL A 1 135 ? 15.27469  -31.75496 41.17916  1.000 36.91749  ? 115 VAL D CA  1 
ATOM   863  C  C   . VAL A 1 135 ? 13.75510  -31.80205 41.04723  1.000 39.16138  ? 115 VAL D C   1 
ATOM   864  O  O   . VAL A 1 135 ? 13.02896  -31.34480 41.93820  1.000 35.26701  ? 115 VAL D O   1 
ATOM   865  C  CB  . VAL A 1 135 ? 15.88283  -30.54747 40.44186  1.000 36.26049  ? 115 VAL D CB  1 
ATOM   866  C  CG1 . VAL A 1 135 ? 15.29701  -29.25189 40.97387  1.000 29.69981  ? 115 VAL D CG1 1 
ATOM   867  C  CG2 . VAL A 1 135 ? 17.39903  -30.54613 40.59859  1.000 35.14817  ? 115 VAL D CG2 1 
ATOM   868  N  N   . GLY A 1 136 ? 13.24813  -32.36314 39.94652  1.000 27.25004  ? 116 GLY D N   1 
ATOM   869  C  CA  . GLY A 1 136 ? 11.80842  -32.52709 39.81372  1.000 18.35014  ? 116 GLY D CA  1 
ATOM   870  C  C   . GLY A 1 136 ? 11.22763  -33.43481 40.88163  1.000 36.43766  ? 116 GLY D C   1 
ATOM   871  O  O   . GLY A 1 136 ? 10.15826  -33.15838 41.43549  1.000 35.87104  ? 116 GLY D O   1 
ATOM   872  N  N   . LEU A 1 137 ? 11.92540  -34.53136 41.18735  1.000 36.24238  ? 117 LEU D N   1 
ATOM   873  C  CA  . LEU A 1 137 ? 11.49001  -35.39758 42.27565  1.000 32.75818  ? 117 LEU D CA  1 
ATOM   874  C  C   . LEU A 1 137 ? 11.53466  -34.66204 43.60777  1.000 36.97470  ? 117 LEU D C   1 
ATOM   875  O  O   . LEU A 1 137 ? 10.63836  -34.82619 44.44029  1.000 33.53142  ? 117 LEU D O   1 
ATOM   876  C  CB  . LEU A 1 137 ? 12.35197  -36.65816 42.32498  1.000 38.14977  ? 117 LEU D CB  1 
ATOM   877  C  CG  . LEU A 1 137 ? 12.07958  -37.60584 43.49456  1.000 35.27000  ? 117 LEU D CG  1 
ATOM   878  C  CD1 . LEU A 1 137 ? 10.67141  -38.17346 43.41131  1.000 34.56394  ? 117 LEU D CD1 1 
ATOM   879  C  CD2 . LEU A 1 137 ? 13.11125  -38.71851 43.52450  1.000 33.38595  ? 117 LEU D CD2 1 
ATOM   880  N  N   . ARG A 1 138 ? 12.56741  -33.84066 43.82359  1.000 37.54174  ? 118 ARG D N   1 
ATOM   881  C  CA  . ARG A 1 138 ? 12.63776  -33.03531 45.04053  1.000 39.77802  ? 118 ARG D CA  1 
ATOM   882  C  C   . ARG A 1 138 ? 11.42357  -32.12382 45.16347  1.000 40.52493  ? 118 ARG D C   1 
ATOM   883  O  O   . ARG A 1 138 ? 10.79887  -32.03999 46.22714  1.000 29.91669  ? 118 ARG D O   1 
ATOM   884  C  CB  . ARG A 1 138 ? 13.92291  -32.20562 45.05552  1.000 37.38533  ? 118 ARG D CB  1 
ATOM   885  C  CG  . ARG A 1 138 ? 15.20652  -33.00710 45.17844  1.000 39.96350  ? 118 ARG D CG  1 
ATOM   886  C  CD  . ARG A 1 138 ? 16.41825  -32.09157 45.07055  1.000 37.97217  ? 118 ARG D CD  1 
ATOM   887  N  NE  . ARG A 1 138 ? 17.66883  -32.83650 44.99448  1.000 53.40474  ? 118 ARG D NE  1 
ATOM   888  C  CZ  . ARG A 1 138 ? 18.45697  -33.08676 46.03028  1.000 54.24416  ? 118 ARG D CZ  1 
ATOM   889  N  NH1 . ARG A 1 138 ? 18.16045  -32.65401 47.24477  1.000 63.11329  ? 118 ARG D NH1 1 
ATOM   890  N  NH2 . ARG A 1 138 ? 19.57140  -33.78733 45.84219  1.000 55.09590  ? 118 ARG D NH2 1 
ATOM   891  N  N   . CYS A 1 139 ? 11.07283  -31.43538 44.07447  1.000 32.52279  ? 119 CYS D N   1 
ATOM   892  C  CA  . CYS A 1 139 ? 9.95254   -30.50168 44.10997  1.000 30.19144  ? 119 CYS D CA  1 
ATOM   893  C  C   . CYS A 1 139 ? 8.63309   -31.22423 44.34310  1.000 29.57388  ? 119 CYS D C   1 
ATOM   894  O  O   . CYS A 1 139 ? 7.80460   -30.76994 45.14054  1.000 36.65172  ? 119 CYS D O   1 
ATOM   895  C  CB  . CYS A 1 139 ? 9.90095   -29.69694 42.81282  1.000 31.73326  ? 119 CYS D CB  1 
ATOM   896  S  SG  . CYS A 1 139 ? 11.34771  -28.65208 42.53895  1.000 32.07324  ? 119 CYS D SG  1 
ATOM   897  N  N   . LEU A 1 140 ? 8.42086   -32.35381 43.66369  1.000 37.90639  ? 120 LEU D N   1 
ATOM   898  C  CA  . LEU A 1 140 ? 7.17396   -33.09159 43.84346  1.000 32.96340  ? 120 LEU D CA  1 
ATOM   899  C  C   . LEU A 1 140 ? 7.07620   -33.68981 45.24207  1.000 34.87407  ? 120 LEU D C   1 
ATOM   900  O  O   . LEU A 1 140 ? 5.99578   -33.69967 45.84406  1.000 32.43749  ? 120 LEU D O   1 
ATOM   901  C  CB  . LEU A 1 140 ? 7.04918   -34.17674 42.77457  1.000 30.20625  ? 120 LEU D CB  1 
ATOM   902  C  CG  . LEU A 1 140 ? 6.41388   -33.69482 41.46828  1.000 38.26425  ? 120 LEU D CG  1 
ATOM   903  C  CD1 . LEU A 1 140 ? 6.49127   -34.75146 40.38090  1.000 33.21081  ? 120 LEU D CD1 1 
ATOM   904  C  CD2 . LEU A 1 140 ? 4.96827   -33.29359 41.71381  1.000 37.51066  ? 120 LEU D CD2 1 
ATOM   905  N  N   . ARG A 1 141 ? 8.18831   -34.20338 45.77196  1.000 38.30186  ? 121 ARG D N   1 
ATOM   906  C  CA  . ARG A 1 141 ? 8.19895   -34.68565 47.14647  1.000 38.79751  ? 121 ARG D CA  1 
ATOM   907  C  C   . ARG A 1 141 ? 7.87518   -33.56225 48.11910  1.000 37.71085  ? 121 ARG D C   1 
ATOM   908  O  O   . ARG A 1 141 ? 7.08249   -33.74777 49.04733  1.000 39.22820  ? 121 ARG D O   1 
ATOM   909  C  CB  . ARG A 1 141 ? 9.55840   -35.30622 47.47129  1.000 40.09116  ? 121 ARG D CB  1 
ATOM   910  C  CG  . ARG A 1 141 ? 9.75910   -36.70397 46.90505  1.000 44.12424  ? 121 ARG D CG  1 
ATOM   911  C  CD  . ARG A 1 141 ? 8.87221   -37.70795 47.62390  1.000 51.36923  ? 121 ARG D CD  1 
ATOM   912  N  NE  . ARG A 1 141 ? 9.19541   -37.78203 49.04433  1.000 60.32082  ? 121 ARG D NE  1 
ATOM   913  C  CZ  . ARG A 1 141 ? 8.41349   -38.32970 49.96465  1.000 63.11676  ? 121 ARG D CZ  1 
ATOM   914  N  NH1 . ARG A 1 141 ? 7.23449   -38.84423 49.65370  1.000 61.07888  ? 121 ARG D NH1 1 
ATOM   915  N  NH2 . ARG A 1 141 ? 8.82256   -38.35765 51.22947  1.000 50.17712  ? 121 ARG D NH2 1 
ATOM   916  N  N   . ARG A 1 142 ? 8.48226   -32.38943 47.92165  1.000 32.53811  ? 122 ARG D N   1 
ATOM   917  C  CA  . ARG A 1 142 ? 8.18862   -31.24358 48.77375  1.000 34.61593  ? 122 ARG D CA  1 
ATOM   918  C  C   . ARG A 1 142 ? 6.71156   -30.87860 48.71324  1.000 39.28326  ? 122 ARG D C   1 
ATOM   919  O  O   . ARG A 1 142 ? 6.09113   -30.60411 49.74552  1.000 31.27775  ? 122 ARG D O   1 
ATOM   920  C  CB  . ARG A 1 142 ? 9.05244   -30.05608 48.35441  1.000 30.28290  ? 122 ARG D CB  1 
ATOM   921  C  CG  . ARG A 1 142 ? 8.85968   -28.80617 49.19141  1.000 32.73055  ? 122 ARG D CG  1 
ATOM   922  C  CD  . ARG A 1 142 ? 9.62920   -28.88769 50.49270  1.000 31.80750  ? 122 ARG D CD  1 
ATOM   923  N  NE  . ARG A 1 142 ? 9.60427   -27.61745 51.20629  1.000 35.39716  ? 122 ARG D NE  1 
ATOM   924  C  CZ  . ARG A 1 142 ? 10.33041  -27.34939 52.28194  1.000 34.97190  ? 122 ARG D CZ  1 
ATOM   925  N  NH1 . ARG A 1 142 ? 11.16098  -28.24212 52.79487  1.000 35.79694  ? 122 ARG D NH1 1 
ATOM   926  N  NH2 . ARG A 1 142 ? 10.22414  -26.15422 52.85412  1.000 26.02729  ? 122 ARG D NH2 1 
ATOM   927  N  N   . ALA A 1 143 ? 6.12989   -30.88369 47.51081  1.000 26.02614  ? 123 ALA D N   1 
ATOM   928  C  CA  . ALA A 1 143 ? 4.71724   -30.54758 47.36703  1.000 29.47114  ? 123 ALA D CA  1 
ATOM   929  C  C   . ALA A 1 143 ? 3.82953   -31.56793 48.06942  1.000 36.27426  ? 123 ALA D C   1 
ATOM   930  O  O   . ALA A 1 143 ? 2.88774   -31.19458 48.77817  1.000 34.58153  ? 123 ALA D O   1 
ATOM   931  C  CB  . ALA A 1 143 ? 4.34936   -30.44016 45.88650  1.000 29.18339  ? 123 ALA D CB  1 
ATOM   932  N  N   . ILE A 1 144 ? 4.11792   -32.86004 47.88740  1.000 33.63867  ? 124 ILE D N   1 
ATOM   933  C  CA  . ILE A 1 144 ? 3.32922   -33.90861 48.53252  1.000 33.90607  ? 124 ILE D CA  1 
ATOM   934  C  C   . ILE A 1 144 ? 3.41333   -33.78263 50.04837  1.000 36.04960  ? 124 ILE D C   1 
ATOM   935  O  O   . ILE A 1 144 ? 2.39555   -33.82918 50.75466  1.000 33.00987  ? 124 ILE D O   1 
ATOM   936  C  CB  . ILE A 1 144 ? 3.79508   -35.29684 48.06033  1.000 40.49709  ? 124 ILE D CB  1 
ATOM   937  C  CG1 . ILE A 1 144 ? 3.45766   -35.50059 46.58255  1.000 35.55714  ? 124 ILE D CG1 1 
ATOM   938  C  CG2 . ILE A 1 144 ? 3.17404   -36.39046 48.91723  1.000 30.16828  ? 124 ILE D CG2 1 
ATOM   939  C  CD1 . ILE A 1 144 ? 4.19672   -36.65307 45.94453  1.000 29.15751  ? 124 ILE D CD1 1 
ATOM   940  N  N   . GLU A 1 145 ? 4.62872   -33.62284 50.57365  1.000 38.41479  ? 125 GLU D N   1 
ATOM   941  C  CA  . GLU A 1 145 ? 4.78943   -33.46258 52.01287  1.000 42.83869  ? 125 GLU D CA  1 
ATOM   942  C  C   . GLU A 1 145 ? 4.00380   -32.25424 52.50603  1.000 44.17255  ? 125 GLU D C   1 
ATOM   943  O  O   . GLU A 1 145 ? 3.11933   -32.38534 53.35624  1.000 44.52571  ? 125 GLU D O   1 
ATOM   944  C  CB  . GLU A 1 145 ? 6.27367   -33.34392 52.36680  1.000 46.28373  ? 125 GLU D CB  1 
ATOM   945  C  CG  . GLU A 1 145 ? 7.10445   -34.56266 51.95368  1.000 61.68761  ? 125 GLU D CG  1 
ATOM   946  C  CD  . GLU A 1 145 ? 7.51343   -35.44373 53.12058  1.000 80.98485  ? 125 GLU D CD  1 
ATOM   947  O  OE1 . GLU A 1 145 ? 8.61781   -35.23304 53.66373  1.000 84.51480  ? 125 GLU D OE1 1 
ATOM   948  O  OE2 . GLU A 1 145 ? 6.73410   -36.34615 53.49179  1.000 75.69432  ? 125 GLU D OE2 1 
ATOM   949  N  N   . THR A 1 146 ? 4.27914   -31.07426 51.93602  1.000 45.77142  ? 126 THR D N   1 
ATOM   950  C  CA  . THR A 1 146 ? 3.62203   -29.84497 52.37377  1.000 32.58425  ? 126 THR D CA  1 
ATOM   951  C  C   . THR A 1 146 ? 2.10359   -29.96821 52.32726  1.000 37.82441  ? 126 THR D C   1 
ATOM   952  O  O   . THR A 1 146 ? 1.40962   -29.48173 53.22749  1.000 35.43102  ? 126 THR D O   1 
ATOM   953  C  CB  . THR A 1 146 ? 4.08677   -28.66857 51.51103  1.000 32.61626  ? 126 THR D CB  1 
ATOM   954  O  OG1 . THR A 1 146 ? 5.51751   -28.62642 51.48475  1.000 36.11456  ? 126 THR D OG1 1 
ATOM   955  C  CG2 . THR A 1 146 ? 3.55872   -27.35626 52.07358  1.000 32.65665  ? 126 THR D CG2 1 
ATOM   956  N  N   . ALA A 1 147 ? 1.56764   -30.62152 51.29258  1.000 43.00299  ? 127 ALA D N   1 
ATOM   957  C  CA  . ALA A 1 147 ? 0.12409   -30.80834 51.21319  1.000 44.96053  ? 127 ALA D CA  1 
ATOM   958  C  C   . ALA A 1 147 ? -0.37165  -31.72465 52.32372  1.000 42.71263  ? 127 ALA D C   1 
ATOM   959  O  O   . ALA A 1 147 ? -1.45390  -31.50548 52.88085  1.000 44.32710  ? 127 ALA D O   1 
ATOM   960  C  CB  . ALA A 1 147 ? -0.25852  -31.36607 49.84239  1.000 31.31105  ? 127 ALA D CB  1 
ATOM   961  N  N   . ALA A 1 148 ? 0.41279   -32.74878 52.66937  1.000 41.97851  ? 128 ALA D N   1 
ATOM   962  C  CA  . ALA A 1 148 ? 0.00394   -33.65491 53.73884  1.000 49.98486  ? 128 ALA D CA  1 
ATOM   963  C  C   . ALA A 1 148 ? 0.04491   -32.96917 55.10502  1.000 43.64895  ? 128 ALA D C   1 
ATOM   964  O  O   . ALA A 1 148 ? -0.86036  -33.15564 55.92715  1.000 39.98286  ? 128 ALA D O   1 
ATOM   965  C  CB  . ALA A 1 148 ? 0.88644   -34.90606 53.72766  1.000 29.67345  ? 128 ALA D CB  1 
ATOM   966  N  N   . GLN A 1 149 ? 1.08347   -32.17105 55.36435  1.000 38.44084  ? 129 GLN D N   1 
ATOM   967  C  CA  . GLN A 1 149 ? 1.22917   -31.52768 56.66796  1.000 40.79865  ? 129 GLN D CA  1 
ATOM   968  C  C   . GLN A 1 149 ? 0.14049   -30.48150 56.88574  1.000 45.95761  ? 129 GLN D C   1 
ATOM   969  O  O   . GLN A 1 149 ? -0.38338  -30.34079 57.99620  1.000 55.97168  ? 129 GLN D O   1 
ATOM   970  C  CB  . GLN A 1 149 ? 2.61626   -30.89537 56.78034  1.000 35.80658  ? 129 GLN D CB  1 
ATOM   971  C  CG  . GLN A 1 149 ? 3.72219   -31.77382 56.20190  1.000 60.76213  ? 129 GLN D CG  1 
ATOM   972  C  CD  . GLN A 1 149 ? 5.10559   -31.37537 56.67975  1.000 63.41536  ? 129 GLN D CD  1 
ATOM   973  O  OE1 . GLN A 1 149 ? 5.51450   -31.73262 57.78425  1.000 65.43262  ? 129 GLN D OE1 1 
ATOM   974  N  NE2 . GLN A 1 149 ? 5.83225   -30.63054 55.85320  1.000 59.52201  ? 129 GLN D NE2 1 
ATOM   975  N  N   . ALA A 1 150 ? -0.21999  -29.72694 55.82543  1.000 44.07983  ? 130 ALA D N   1 
ATOM   976  C  CA  . ALA A 1 150 ? -1.35033  -28.79269 55.87482  1.000 41.24190  ? 130 ALA D CA  1 
ATOM   977  C  C   . ALA A 1 150 ? -2.70410  -29.51286 56.05112  1.000 47.96350  ? 130 ALA D C   1 
ATOM   978  O  O   . ALA A 1 150 ? -3.72695  -28.84469 55.92951  1.000 45.93742  ? 130 ALA D O   1 
ATOM   979  C  CB  . ALA A 1 150 ? -1.39522  -27.93880 54.60998  1.000 32.34640  ? 130 ALA D CB  1 
ATOM   980  N  N   . GLY A 1 151 ? -2.74189  -30.81687 56.33022  1.000 45.98393  ? 131 GLY D N   1 
ATOM   981  C  CA  . GLY A 1 151 ? -4.00504  -31.51783 56.52243  1.000 34.92174  ? 131 GLY D CA  1 
ATOM   982  C  C   . GLY A 1 151 ? -4.70046  -31.94420 55.25113  1.000 56.21289  ? 131 GLY D C   1 
ATOM   983  O  O   . GLY A 1 151 ? -5.92873  -32.08467 55.24148  1.000 60.17608  ? 131 GLY D O   1 
ATOM   984  N  N   . GLY A 1 152 ? -3.94616  -32.17272 54.17830  1.000 53.43667  ? 132 GLY D N   1 
ATOM   985  C  CA  . GLY A 1 152 ? -4.55515  -32.42003 52.88422  1.000 50.33954  ? 132 GLY D CA  1 
ATOM   986  C  C   . GLY A 1 152 ? -5.08607  -33.83744 52.74193  1.000 42.99258  ? 132 GLY D C   1 
ATOM   987  O  O   . GLY A 1 152 ? -4.47921  -34.80627 53.19863  1.000 45.30793  ? 132 GLY D O   1 
ATOM   988  N  N   . ASP A 1 153 ? -6.24599  -33.94170 52.09547  1.000 44.80042  ? 133 ASP D N   1 
ATOM   989  C  CA  . ASP A 1 153 ? -6.84532  -35.22431 51.75655  1.000 45.32881  ? 133 ASP D CA  1 
ATOM   990  C  C   . ASP A 1 153 ? -6.33232  -35.76450 50.42921  1.000 53.01976  ? 133 ASP D C   1 
ATOM   991  O  O   . ASP A 1 153 ? -6.29885  -36.98535 50.23181  1.000 43.49190  ? 133 ASP D O   1 
ATOM   992  C  CB  . ASP A 1 153 ? -8.36885  -35.08018 51.69803  1.000 50.65854  ? 133 ASP D CB  1 
ATOM   993  C  CG  . ASP A 1 153 ? -9.08998  -36.40619 51.79793  1.000 49.29446  ? 133 ASP D CG  1 
ATOM   994  O  OD1 . ASP A 1 153 ? -8.41528  -37.44966 51.91135  1.000 65.99415  ? 133 ASP D OD1 1 
ATOM   995  O  OD2 . ASP A 1 153 ? -10.33956 -36.40339 51.76852  1.000 59.60589  ? 133 ASP D OD2 1 
ATOM   996  N  N   . ALA A 1 154 ? -5.93291  -34.88149 49.51741  1.000 41.27063  ? 134 ALA D N   1 
ATOM   997  C  CA  . ALA A 1 154 ? -5.45184  -35.29059 48.20737  1.000 31.41775  ? 134 ALA D CA  1 
ATOM   998  C  C   . ALA A 1 154 ? -4.69381  -34.13083 47.58443  1.000 40.00477  ? 134 ALA D C   1 
ATOM   999  O  O   . ALA A 1 154 ? -4.88268  -32.97018 47.95775  1.000 43.61926  ? 134 ALA D O   1 
ATOM   1000 C  CB  . ALA A 1 154 ? -6.60039  -35.72900 47.29650  1.000 29.99019  ? 134 ALA D CB  1 
ATOM   1001 N  N   . LEU A 1 155 ? -3.83250  -34.46084 46.62558  1.000 33.53379  ? 135 LEU D N   1 
ATOM   1002 C  CA  . LEU A 1 155 ? -3.11383  -33.46630 45.83643  1.000 29.40491  ? 135 LEU D CA  1 
ATOM   1003 C  C   . LEU A 1 155 ? -3.52935  -33.63973 44.38262  1.000 32.14733  ? 135 LEU D C   1 
ATOM   1004 O  O   . LEU A 1 155 ? -3.25818  -34.67974 43.77267  1.000 38.18100  ? 135 LEU D O   1 
ATOM   1005 C  CB  . LEU A 1 155 ? -1.60213  -33.60386 46.00308  1.000 29.97282  ? 135 LEU D CB  1 
ATOM   1006 C  CG  . LEU A 1 155 ? -0.77398  -32.48995 45.35914  1.000 31.34137  ? 135 LEU D CG  1 
ATOM   1007 C  CD1 . LEU A 1 155 ? -1.30328  -31.12124 45.76449  1.000 33.25074  ? 135 LEU D CD1 1 
ATOM   1008 C  CD2 . LEU A 1 155 ? 0.68413   -32.63091 45.74497  1.000 30.24822  ? 135 LEU D CD2 1 
ATOM   1009 N  N   . ARG A 1 156 ? -4.20510  -32.63425 43.83959  1.000 36.34077  ? 136 ARG D N   1 
ATOM   1010 C  CA  . ARG A 1 156 ? -4.68400  -32.65409 42.46794  1.000 33.11938  ? 136 ARG D CA  1 
ATOM   1011 C  C   . ARG A 1 156 ? -3.84109  -31.72015 41.61183  1.000 35.98451  ? 136 ARG D C   1 
ATOM   1012 O  O   . ARG A 1 156 ? -3.32742  -30.70405 42.08965  1.000 38.03403  ? 136 ARG D O   1 
ATOM   1013 C  CB  . ARG A 1 156 ? -6.15799  -32.25169 42.39465  1.000 28.63150  ? 136 ARG D CB  1 
ATOM   1014 C  CG  . ARG A 1 156 ? -7.09734  -33.24370 43.06415  1.000 29.14822  ? 136 ARG D CG  1 
ATOM   1015 C  CD  . ARG A 1 156 ? -8.51938  -32.71943 43.13153  1.000 26.37030  ? 136 ARG D CD  1 
ATOM   1016 N  NE  . ARG A 1 156 ? -9.42905  -33.69658 43.71749  1.000 36.62627  ? 136 ARG D NE  1 
ATOM   1017 C  CZ  . ARG A 1 156 ? -10.70829 -33.46852 43.98593  1.000 40.98109  ? 136 ARG D CZ  1 
ATOM   1018 N  NH1 . ARG A 1 156 ? -11.26583 -32.29086 43.75433  1.000 31.36599  ? 136 ARG D NH1 1 
ATOM   1019 N  NH2 . ARG A 1 156 ? -11.44786 -34.44761 44.49961  1.000 53.32754  ? 136 ARG D NH2 1 
ATOM   1020 N  N   . SER A 1 157 ? -3.70023  -32.07572 40.33782  1.000 32.51345  ? 137 SER D N   1 
ATOM   1021 C  CA  . SER A 1 157 ? -2.85955  -31.29669 39.44405  1.000 29.84417  ? 137 SER D CA  1 
ATOM   1022 C  C   . SER A 1 157 ? -3.36422  -31.44363 38.01767  1.000 30.47783  ? 137 SER D C   1 
ATOM   1023 O  O   . SER A 1 157 ? -4.04937  -32.40956 37.67531  1.000 34.85284  ? 137 SER D O   1 
ATOM   1024 C  CB  . SER A 1 157 ? -1.39058  -31.72841 39.54052  1.000 32.54378  ? 137 SER D CB  1 
ATOM   1025 O  OG  . SER A 1 157 ? -0.55224  -30.84597 38.81359  1.000 41.24822  ? 137 SER D OG  1 
ATOM   1026 N  N   . GLU A 1 158 ? -3.01944  -30.46356 37.18918  1.000 35.28150  ? 138 GLU D N   1 
ATOM   1027 C  CA  . GLU A 1 158 ? -3.27461  -30.50887 35.75803  1.000 29.98448  ? 138 GLU D CA  1 
ATOM   1028 C  C   . GLU A 1 158 ? -1.94128  -30.65329 35.04142  1.000 36.51340  ? 138 GLU D C   1 
ATOM   1029 O  O   . GLU A 1 158 ? -1.02637  -29.85562 35.26706  1.000 40.19924  ? 138 GLU D O   1 
ATOM   1030 C  CB  . GLU A 1 158 ? -4.00300  -29.24925 35.28680  1.000 23.07098  ? 138 GLU D CB  1 
ATOM   1031 C  CG  . GLU A 1 158 ? -4.45154  -29.31539 33.84034  1.000 31.92222  ? 138 GLU D CG  1 
ATOM   1032 C  CD  . GLU A 1 158 ? -5.16507  -28.05799 33.39410  1.000 45.83710  ? 138 GLU D CD  1 
ATOM   1033 O  OE1 . GLU A 1 158 ? -4.48612  -27.03816 33.15228  1.000 38.61753  ? 138 GLU D OE1 1 
ATOM   1034 O  OE2 . GLU A 1 158 ? -6.40923  -28.08879 33.29192  1.000 53.58410  ? 138 GLU D OE2 1 
ATOM   1035 N  N   . ALA A 1 159 ? -1.82646  -31.66805 34.18924  1.000 28.02975  ? 139 ALA D N   1 
ATOM   1036 C  CA  . ALA A 1 159 ? -0.56657  -31.95768 33.52259  1.000 36.82395  ? 139 ALA D CA  1 
ATOM   1037 C  C   . ALA A 1 159 ? -0.75651  -31.99148 32.01332  1.000 27.94363  ? 139 ALA D C   1 
ATOM   1038 O  O   . ALA A 1 159 ? -1.86019  -32.19883 31.50471  1.000 29.54082  ? 139 ALA D O   1 
ATOM   1039 C  CB  . ALA A 1 159 ? 0.03387   -33.28972 33.99657  1.000 25.03807  ? 139 ALA D CB  1 
ATOM   1040 N  N   . ASN A 1 160 ? 0.34869   -31.77867 31.29982  1.000 31.83212  ? 140 ASN D N   1 
ATOM   1041 C  CA  . ASN A 1 160 ? 0.37612   -31.96108 29.85882  1.000 30.62429  ? 140 ASN D CA  1 
ATOM   1042 C  C   . ASN A 1 160 ? 0.90169   -33.35703 29.57085  1.000 33.06296  ? 140 ASN D C   1 
ATOM   1043 O  O   . ASN A 1 160 ? 2.09352   -33.61595 29.79847  1.000 37.43883  ? 140 ASN D O   1 
ATOM   1044 C  CB  . ASN A 1 160 ? 1.26028   -30.90745 29.19428  1.000 31.01380  ? 140 ASN D CB  1 
ATOM   1045 C  CG  . ASN A 1 160 ? 1.12011   -30.89180 27.67677  1.000 38.71238  ? 140 ASN D CG  1 
ATOM   1046 O  OD1 . ASN A 1 160 ? 0.88412   -31.92462 27.04933  1.000 38.28396  ? 140 ASN D OD1 1 
ATOM   1047 N  ND2 . ASN A 1 160 ? 1.26166   -29.71242 27.08241  1.000 35.74886  ? 140 ASN D ND2 1 
ATOM   1048 N  N   . PRO A 1 161 ? 0.07103   -34.28555 29.09050  1.000 39.15863  ? 141 PRO D N   1 
ATOM   1049 C  CA  . PRO A 1 161 ? 0.57004   -35.64418 28.82228  1.000 40.98176  ? 141 PRO D CA  1 
ATOM   1050 C  C   . PRO A 1 161 ? 1.63082   -35.69693 27.73789  1.000 32.46226  ? 141 PRO D C   1 
ATOM   1051 O  O   . PRO A 1 161 ? 2.36083   -36.69272 27.65635  1.000 36.34251  ? 141 PRO D O   1 
ATOM   1052 C  CB  . PRO A 1 161 ? -0.69595  -36.40877 28.40889  1.000 32.96854  ? 141 PRO D CB  1 
ATOM   1053 C  CG  . PRO A 1 161 ? -1.61675  -35.35286 27.89364  1.000 30.87489  ? 141 PRO D CG  1 
ATOM   1054 C  CD  . PRO A 1 161 ? -1.35398  -34.14372 28.74810  1.000 35.38757  ? 141 PRO D CD  1 
ATOM   1055 N  N   . ASP A 1 162 ? 1.74582   -34.66128 26.90542  1.000 36.96124  ? 142 ASP D N   1 
ATOM   1056 C  CA  . ASP A 1 162 ? 2.77997   -34.62880 25.88055  1.000 46.36954  ? 142 ASP D CA  1 
ATOM   1057 C  C   . ASP A 1 162 ? 4.15459   -34.28138 26.43556  1.000 35.55530  ? 142 ASP D C   1 
ATOM   1058 O  O   . ASP A 1 162 ? 5.13990   -34.37413 25.69742  1.000 35.18393  ? 142 ASP D O   1 
ATOM   1059 C  CB  . ASP A 1 162 ? 2.39590   -33.63946 24.77786  1.000 40.09519  ? 142 ASP D CB  1 
ATOM   1060 C  CG  . ASP A 1 162 ? 1.15646   -34.07294 24.01834  1.000 46.23700  ? 142 ASP D CG  1 
ATOM   1061 O  OD1 . ASP A 1 162 ? 0.93267   -35.29518 23.89635  1.000 40.82332  ? 142 ASP D OD1 1 
ATOM   1062 O  OD2 . ASP A 1 162 ? 0.40566   -33.19518 23.54409  1.000 55.37294  ? 142 ASP D OD2 1 
ATOM   1063 N  N   . LEU A 1 163 ? 4.24576   -33.87860 27.70280  1.000 34.31443  ? 143 LEU D N   1 
ATOM   1064 C  CA  . LEU A 1 163 ? 5.53129   -33.70983 28.38109  1.000 28.54598  ? 143 LEU D CA  1 
ATOM   1065 C  C   . LEU A 1 163 ? 5.85153   -35.03952 29.05373  1.000 37.48695  ? 143 LEU D C   1 
ATOM   1066 O  O   . LEU A 1 163 ? 5.50228   -35.27807 30.21112  1.000 40.42535  ? 143 LEU D O   1 
ATOM   1067 C  CB  . LEU A 1 163 ? 5.47547   -32.55408 29.37277  1.000 35.75089  ? 143 LEU D CB  1 
ATOM   1068 C  CG  . LEU A 1 163 ? 5.08504   -31.19118 28.78700  1.000 34.60619  ? 143 LEU D CG  1 
ATOM   1069 C  CD1 . LEU A 1 163 ? 5.15352   -30.08856 29.83956  1.000 30.00808  ? 143 LEU D CD1 1 
ATOM   1070 C  CD2 . LEU A 1 163 ? 5.95909   -30.84808 27.59431  1.000 34.78268  ? 143 LEU D CD2 1 
ATOM   1071 N  N   . SER A 1 164 ? 6.54099   -35.91223 28.31111  1.000 34.39424  ? 144 SER D N   1 
ATOM   1072 C  CA  . SER A 1 164 ? 6.62480   -37.32349 28.68242  1.000 28.61048  ? 144 SER D CA  1 
ATOM   1073 C  C   . SER A 1 164 ? 7.34460   -37.53148 30.00970  1.000 34.57511  ? 144 SER D C   1 
ATOM   1074 O  O   . SER A 1 164 ? 6.91695   -38.35299 30.82917  1.000 34.18201  ? 144 SER D O   1 
ATOM   1075 C  CB  . SER A 1 164 ? 7.32300   -38.11506 27.57581  1.000 27.63339  ? 144 SER D CB  1 
ATOM   1076 O  OG  . SER A 1 164 ? 6.60283   -38.03618 26.35897  1.000 46.14335  ? 144 SER D OG  1 
ATOM   1077 N  N   . ALA A 1 165 ? 8.45025   -36.81922 30.23403  1.000 32.16069  ? 145 ALA D N   1 
ATOM   1078 C  CA  . ALA A 1 165 ? 9.23974   -37.05633 31.43902  1.000 30.06719  ? 145 ALA D CA  1 
ATOM   1079 C  C   . ALA A 1 165 ? 8.45799   -36.67661 32.68991  1.000 32.05021  ? 145 ALA D C   1 
ATOM   1080 O  O   . ALA A 1 165 ? 8.37855   -37.45433 33.64948  1.000 37.44213  ? 145 ALA D O   1 
ATOM   1081 C  CB  . ALA A 1 165 ? 10.55594  -36.28398 31.36589  1.000 24.97706  ? 145 ALA D CB  1 
ATOM   1082 N  N   . THR A 1 166 ? 7.86824   -35.47964 32.69332  1.000 31.33749  ? 146 THR D N   1 
ATOM   1083 C  CA  . THR A 1 166 ? 7.08626   -35.04157 33.84394  1.000 31.85927  ? 146 THR D CA  1 
ATOM   1084 C  C   . THR A 1 166 ? 5.86181   -35.92513 34.04543  1.000 38.04456  ? 146 THR D C   1 
ATOM   1085 O  O   . THR A 1 166 ? 5.50076   -36.24872 35.18365  1.000 31.87969  ? 146 THR D O   1 
ATOM   1086 C  CB  . THR A 1 166 ? 6.67105   -33.58153 33.66582  1.000 35.14552  ? 146 THR D CB  1 
ATOM   1087 O  OG1 . THR A 1 166 ? 7.83401   -32.78284 33.40991  1.000 40.41365  ? 146 THR D OG1 1 
ATOM   1088 C  CG2 . THR A 1 166 ? 5.97339   -33.06931 34.91576  1.000 40.53928  ? 146 THR D CG2 1 
ATOM   1089 N  N   . ARG A 1 167 ? 5.21046   -36.32531 32.94922  1.000 33.90877  ? 147 ARG D N   1 
ATOM   1090 C  CA  . ARG A 1 167 ? 4.04817   -37.20183 33.05330  1.000 35.29335  ? 147 ARG D CA  1 
ATOM   1091 C  C   . ARG A 1 167 ? 4.42299   -38.53559 33.68600  1.000 36.19505  ? 147 ARG D C   1 
ATOM   1092 O  O   . ARG A 1 167 ? 3.69647   -39.05469 34.54377  1.000 30.47344  ? 147 ARG D O   1 
ATOM   1093 C  CB  . ARG A 1 167 ? 3.43188   -37.41538 31.66971  1.000 35.10728  ? 147 ARG D CB  1 
ATOM   1094 C  CG  . ARG A 1 167 ? 2.14985   -38.23285 31.67129  1.000 32.07006  ? 147 ARG D CG  1 
ATOM   1095 C  CD  . ARG A 1 167 ? 1.01972   -37.48826 32.37104  1.000 35.62313  ? 147 ARG D CD  1 
ATOM   1096 N  NE  . ARG A 1 167 ? -0.18382  -38.30628 32.46293  1.000 33.61255  ? 147 ARG D NE  1 
ATOM   1097 C  CZ  . ARG A 1 167 ? -0.42356  -39.17451 33.43607  1.000 32.38591  ? 147 ARG D CZ  1 
ATOM   1098 N  NH1 . ARG A 1 167 ? 0.43325   -39.35412 34.42891  1.000 29.44804  ? 147 ARG D NH1 1 
ATOM   1099 N  NH2 . ARG A 1 167 ? -1.54795  -39.88412 33.40995  1.000 31.82546  ? 147 ARG D NH2 1 
ATOM   1100 N  N   . SER A 1 168 ? 5.56494   -39.09832 33.28456  1.000 33.66587  ? 148 SER D N   1 
ATOM   1101 C  CA  . SER A 1 168 ? 6.00487   -40.36538 33.85432  1.000 29.40867  ? 148 SER D CA  1 
ATOM   1102 C  C   . SER A 1 168 ? 6.38906   -40.20683 35.31969  1.000 34.37550  ? 148 SER D C   1 
ATOM   1103 O  O   . SER A 1 168 ? 6.09962   -41.08601 36.13728  1.000 35.48013  ? 148 SER D O   1 
ATOM   1104 C  CB  . SER A 1 168 ? 7.17288   -40.92406 33.04328  1.000 37.05930  ? 148 SER D CB  1 
ATOM   1105 O  OG  . SER A 1 168 ? 7.59193   -42.17771 33.55093  1.000 54.24114  ? 148 SER D OG  1 
ATOM   1106 N  N   . LEU A 1 169 ? 7.03731   -39.09258 35.67338  1.000 33.41207  ? 149 LEU D N   1 
ATOM   1107 C  CA  . LEU A 1 169 ? 7.37332   -38.85464 37.07561  1.000 37.13316  ? 149 LEU D CA  1 
ATOM   1108 C  C   . LEU A 1 169 ? 6.11659   -38.73360 37.93088  1.000 34.64752  ? 149 LEU D C   1 
ATOM   1109 O  O   . LEU A 1 169 ? 6.07205   -39.23967 39.05878  1.000 32.22375  ? 149 LEU D O   1 
ATOM   1110 C  CB  . LEU A 1 169 ? 8.23854   -37.59984 37.21181  1.000 30.51519  ? 149 LEU D CB  1 
ATOM   1111 C  CG  . LEU A 1 169 ? 8.57608   -37.18340 38.64732  1.000 26.03346  ? 149 LEU D CG  1 
ATOM   1112 C  CD1 . LEU A 1 169 ? 9.24995   -38.32283 39.39690  1.000 31.35992  ? 149 LEU D CD1 1 
ATOM   1113 C  CD2 . LEU A 1 169 ? 9.44936   -35.93491 38.66911  1.000 28.52108  ? 149 LEU D CD2 1 
ATOM   1114 N  N   . LEU A 1 170 ? 5.08498   -38.06387 37.41193  1.000 30.91658  ? 150 LEU D N   1 
ATOM   1115 C  CA  . LEU A 1 170 ? 3.82371   -37.97397 38.14095  1.000 31.57320  ? 150 LEU D CA  1 
ATOM   1116 C  C   . LEU A 1 170 ? 3.16372   -39.34175 38.26807  1.000 37.59407  ? 150 LEU D C   1 
ATOM   1117 O  O   . LEU A 1 170 ? 2.60235   -39.67188 39.31950  1.000 34.19038  ? 150 LEU D O   1 
ATOM   1118 C  CB  . LEU A 1 170 ? 2.88564   -36.98403 37.44864  1.000 34.76446  ? 150 LEU D CB  1 
ATOM   1119 C  CG  . LEU A 1 170 ? 3.31034   -35.51289 37.47386  1.000 27.91885  ? 150 LEU D CG  1 
ATOM   1120 C  CD1 . LEU A 1 170 ? 2.60941   -34.72649 36.37769  1.000 24.42716  ? 150 LEU D CD1 1 
ATOM   1121 C  CD2 . LEU A 1 170 ? 3.03478   -34.89050 38.83659  1.000 28.85151  ? 150 LEU D CD2 1 
ATOM   1122 N  N   . ASP A 1 171 ? 3.22792   -40.15457 37.21086  1.000 31.56433  ? 151 ASP D N   1 
ATOM   1123 C  CA  . ASP A 1 171 ? 2.63585   -41.48717 37.27206  1.000 33.67815  ? 151 ASP D CA  1 
ATOM   1124 C  C   . ASP A 1 171 ? 3.35736   -42.37328 38.28100  1.000 35.96208  ? 151 ASP D C   1 
ATOM   1125 O  O   . ASP A 1 171 ? 2.71769   -43.13744 39.01181  1.000 34.43913  ? 151 ASP D O   1 
ATOM   1126 C  CB  . ASP A 1 171 ? 2.65225   -42.13037 35.88704  1.000 35.47112  ? 151 ASP D CB  1 
ATOM   1127 C  CG  . ASP A 1 171 ? 2.08248   -43.53087 35.89056  1.000 38.67369  ? 151 ASP D CG  1 
ATOM   1128 O  OD1 . ASP A 1 171 ? 0.85413   -43.67478 36.06867  1.000 41.38717  ? 151 ASP D OD1 1 
ATOM   1129 O  OD2 . ASP A 1 171 ? 2.86428   -44.49007 35.71899  1.000 42.84534  ? 151 ASP D OD2 1 
ATOM   1130 N  N   . ILE A 1 172 ? 4.68668   -42.28490 38.33725  1.000 36.99830  ? 152 ILE D N   1 
ATOM   1131 C  CA  . ILE A 1 172 ? 5.45250   -43.12320 39.25431  1.000 38.07526  ? 152 ILE D CA  1 
ATOM   1132 C  C   . ILE A 1 172 ? 5.18353   -42.72379 40.69995  1.000 36.38876  ? 152 ILE D C   1 
ATOM   1133 O  O   . ILE A 1 172 ? 5.11283   -43.57950 41.59126  1.000 37.30086  ? 152 ILE D O   1 
ATOM   1134 C  CB  . ILE A 1 172 ? 6.95200   -43.05005 38.90938  1.000 35.92624  ? 152 ILE D CB  1 
ATOM   1135 C  CG1 . ILE A 1 172 ? 7.21245   -43.69850 37.54370  1.000 34.33705  ? 152 ILE D CG1 1 
ATOM   1136 C  CG2 . ILE A 1 172 ? 7.79088   -43.71953 39.99224  1.000 26.18837  ? 152 ILE D CG2 1 
ATOM   1137 C  CD1 . ILE A 1 172 ? 8.60491   -43.45285 37.00356  1.000 40.86157  ? 152 ILE D CD1 1 
ATOM   1138 N  N   . LEU A 1 173 ? 5.00920   -41.42712 40.95573  1.000 35.64475  ? 153 LEU D N   1 
ATOM   1139 C  CA  . LEU A 1 173 ? 4.74776   -40.94795 42.30774  1.000 35.66441  ? 153 LEU D CA  1 
ATOM   1140 C  C   . LEU A 1 173 ? 3.31399   -41.19569 42.76510  1.000 35.43539  ? 153 LEU D C   1 
ATOM   1141 O  O   . LEU A 1 173 ? 2.96639   -40.82457 43.89280  1.000 35.18894  ? 153 LEU D O   1 
ATOM   1142 C  CB  . LEU A 1 173 ? 5.06688   -39.45282 42.41241  1.000 32.60775  ? 153 LEU D CB  1 
ATOM   1143 C  CG  . LEU A 1 173 ? 6.54867   -39.06276 42.36663  1.000 34.32822  ? 153 LEU D CG  1 
ATOM   1144 C  CD1 . LEU A 1 173 ? 6.76091   -37.72823 43.06415  1.000 43.21695  ? 153 LEU D CD1 1 
ATOM   1145 C  CD2 . LEU A 1 173 ? 7.43340   -40.13865 42.98558  1.000 37.67992  ? 153 LEU D CD2 1 
ATOM   1146 N  N   . GLY A 1 174 ? 2.47736   -41.80547 41.93194  1.000 33.89165  ? 154 GLY D N   1 
ATOM   1147 C  CA  . GLY A 1 174 ? 1.14475   -42.19146 42.33836  1.000 32.75499  ? 154 GLY D CA  1 
ATOM   1148 C  C   . GLY A 1 174 ? 0.02206   -41.28462 41.88959  1.000 32.04596  ? 154 GLY D C   1 
ATOM   1149 O  O   . GLY A 1 174 ? -1.10963  -41.46677 42.34687  1.000 35.58958  ? 154 GLY D O   1 
ATOM   1150 N  N   . PHE A 1 175 ? 0.29151   -40.31223 41.02323  1.000 33.00082  ? 155 PHE D N   1 
ATOM   1151 C  CA  . PHE A 1 175 ? -0.77243  -39.47347 40.48363  1.000 34.08020  ? 155 PHE D CA  1 
ATOM   1152 C  C   . PHE A 1 175 ? -1.56734  -40.27105 39.45861  1.000 37.32674  ? 155 PHE D C   1 
ATOM   1153 O  O   . PHE A 1 175 ? -1.01771  -40.71141 38.44406  1.000 37.89267  ? 155 PHE D O   1 
ATOM   1154 C  CB  . PHE A 1 175 ? -0.19276  -38.20659 39.85742  1.000 37.06943  ? 155 PHE D CB  1 
ATOM   1155 C  CG  . PHE A 1 175 ? 0.28994   -37.19686 40.86255  1.000 33.48238  ? 155 PHE D CG  1 
ATOM   1156 C  CD1 . PHE A 1 175 ? 1.54713   -37.31236 41.43435  1.000 31.14559  ? 155 PHE D CD1 1 
ATOM   1157 C  CD2 . PHE A 1 175 ? -0.51147  -36.12609 41.22615  1.000 36.83384  ? 155 PHE D CD2 1 
ATOM   1158 C  CE1 . PHE A 1 175 ? 1.99216   -36.38078 42.35635  1.000 32.54354  ? 155 PHE D CE1 1 
ATOM   1159 C  CE2 . PHE A 1 175 ? -0.06913  -35.19028 42.14794  1.000 29.81202  ? 155 PHE D CE2 1 
ATOM   1160 C  CZ  . PHE A 1 175 ? 1.18350   -35.31972 42.71208  1.000 33.48484  ? 155 PHE D CZ  1 
ATOM   1161 N  N   . VAL A 1 176 ? -2.85181  -40.47116 39.73021  1.000 34.08310  ? 156 VAL D N   1 
ATOM   1162 C  CA  . VAL A 1 176 ? -3.72492  -41.27041 38.87963  1.000 29.13987  ? 156 VAL D CA  1 
ATOM   1163 C  C   . VAL A 1 176 ? -4.57915  -40.34098 38.03132  1.000 30.03633  ? 156 VAL D C   1 
ATOM   1164 O  O   . VAL A 1 176 ? -5.09913  -39.33089 38.52448  1.000 34.50983  ? 156 VAL D O   1 
ATOM   1165 C  CB  . VAL A 1 176 ? -4.60297  -42.21424 39.72521  1.000 39.54461  ? 156 VAL D CB  1 
ATOM   1166 C  CG1 . VAL A 1 176 ? -5.59033  -42.96329 38.84253  1.000 37.74749  ? 156 VAL D CG1 1 
ATOM   1167 C  CG2 . VAL A 1 176 ? -3.73172  -43.19059 40.51150  1.000 30.88018  ? 156 VAL D CG2 1 
ATOM   1168 N  N   . GLN A 1 177 ? -4.71103  -40.67124 36.74901  1.000 25.74683  ? 157 GLN D N   1 
ATOM   1169 C  CA  . GLN A 1 177 ? -5.62491  -39.97380 35.85707  1.000 33.35360  ? 157 GLN D CA  1 
ATOM   1170 C  C   . GLN A 1 177 ? -6.99353  -40.63395 35.96659  1.000 37.54855  ? 157 GLN D C   1 
ATOM   1171 O  O   . GLN A 1 177 ? -7.12070  -41.84712 35.77376  1.000 48.41534  ? 157 GLN D O   1 
ATOM   1172 C  CB  . GLN A 1 177 ? -5.10981  -40.00526 34.41742  1.000 26.99721  ? 157 GLN D CB  1 
ATOM   1173 C  CG  . GLN A 1 177 ? -6.02006  -39.33595 33.40416  1.000 28.93350  ? 157 GLN D CG  1 
ATOM   1174 C  CD  . GLN A 1 177 ? -5.45326  -39.38147 31.99332  1.000 38.99518  ? 157 GLN D CD  1 
ATOM   1175 O  OE1 . GLN A 1 177 ? -4.26492  -39.63204 31.79712  1.000 33.44511  ? 157 GLN D OE1 1 
ATOM   1176 N  NE2 . GLN A 1 177 ? -6.30740  -39.14209 31.00273  1.000 26.39372  ? 157 GLN D NE2 1 
ATOM   1177 N  N   . HIS A 1 178 ? -8.01244  -39.84180 36.28648  1.000 42.54055  ? 158 HIS D N   1 
ATOM   1178 C  CA  . HIS A 1 178 ? -9.35191  -40.37303 36.51164  1.000 52.95110  ? 158 HIS D CA  1 
ATOM   1179 C  C   . HIS A 1 178 ? -10.30826 -40.08768 35.36353  1.000 54.25075  ? 158 HIS D C   1 
ATOM   1180 O  O   . HIS A 1 178 ? -11.08476 -40.96710 34.98346  1.000 43.87803  ? 158 HIS D O   1 
ATOM   1181 C  CB  . HIS A 1 178 ? -9.92792  -39.80697 37.81353  1.000 49.30150  ? 158 HIS D CB  1 
ATOM   1182 C  CG  . HIS A 1 178 ? -11.09824 -40.57484 38.34863  1.000 63.09086  ? 158 HIS D CG  1 
ATOM   1183 N  ND1 . HIS A 1 178 ? -12.39566 -40.11589 38.25827  1.000 65.04511  ? 158 HIS D ND1 1 
ATOM   1184 C  CD2 . HIS A 1 178 ? -11.16523 -41.76753 38.98725  1.000 62.73631  ? 158 HIS D CD2 1 
ATOM   1185 C  CE1 . HIS A 1 178 ? -13.21087 -40.99321 38.81658  1.000 56.14601  ? 158 HIS D CE1 1 
ATOM   1186 N  NE2 . HIS A 1 178 ? -12.48964 -42.00443 39.26662  1.000 61.82703  ? 158 HIS D NE2 1 
ATOM   1187 N  N   . GLY A 1 179 ? -10.26440 -38.88370 34.79883  1.000 42.78035  ? 159 GLY D N   1 
ATOM   1188 C  CA  . GLY A 1 179 ? -11.11170 -38.52698 33.68931  1.000 35.13558  ? 159 GLY D CA  1 
ATOM   1189 C  C   . GLY A 1 179 ? -10.39883 -38.64879 32.35884  1.000 37.90035  ? 159 GLY D C   1 
ATOM   1190 O  O   . GLY A 1 179 ? -9.23587  -39.04771 32.28080  1.000 41.61434  ? 159 GLY D O   1 
ATOM   1191 N  N   . PRO A 1 180 ? -11.09163 -38.30827 31.27766  1.000 37.65324  ? 160 PRO D N   1 
ATOM   1192 C  CA  . PRO A 1 180 ? -10.48859 -38.41317 29.94500  1.000 42.92021  ? 160 PRO D CA  1 
ATOM   1193 C  C   . PRO A 1 180 ? -9.50869  -37.28287 29.66329  1.000 41.44236  ? 160 PRO D C   1 
ATOM   1194 O  O   . PRO A 1 180 ? -9.50653  -36.23797 30.31670  1.000 41.68828  ? 160 PRO D O   1 
ATOM   1195 C  CB  . PRO A 1 180 ? -11.69828 -38.33075 29.00505  1.000 44.87590  ? 160 PRO D CB  1 
ATOM   1196 C  CG  . PRO A 1 180 ? -12.69940 -37.53449 29.77256  1.000 51.41240  ? 160 PRO D CG  1 
ATOM   1197 C  CD  . PRO A 1 180 ? -12.50808 -37.89953 31.21239  1.000 37.57158  ? 160 PRO D CD  1 
ATOM   1198 N  N   . THR A 1 181 ? -8.66510  -37.52337 28.66286  1.000 39.66462  ? 161 THR D N   1 
ATOM   1199 C  CA  . THR A 1 181 ? -7.71902  -36.52500 28.18440  1.000 30.49469  ? 161 THR D CA  1 
ATOM   1200 C  C   . THR A 1 181 ? -8.45486  -35.46297 27.37787  1.000 32.43764  ? 161 THR D C   1 
ATOM   1201 O  O   . THR A 1 181 ? -9.26782  -35.78539 26.50552  1.000 36.41162  ? 161 THR D O   1 
ATOM   1202 C  CB  . THR A 1 181 ? -6.63298  -37.18289 27.32868  1.000 31.51480  ? 161 THR D CB  1 
ATOM   1203 O  OG1 . THR A 1 181 ? -5.94512  -38.16986 28.10856  1.000 36.20336  ? 161 THR D OG1 1 
ATOM   1204 C  CG2 . THR A 1 181 ? -5.63198  -36.14759 26.82709  1.000 24.32397  ? 161 THR D CG2 1 
ATOM   1205 N  N   . LEU A 1 182 ? -8.16400  -34.19801 27.66538  1.000 33.14887  ? 162 LEU D N   1 
ATOM   1206 C  CA  . LEU A 1 182 ? -8.86036  -33.07385 27.06032  1.000 34.75941  ? 162 LEU D CA  1 
ATOM   1207 C  C   . LEU A 1 182 ? -7.96718  -32.38347 26.04073  1.000 35.63510  ? 162 LEU D C   1 
ATOM   1208 O  O   . LEU A 1 182 ? -6.75298  -32.27064 26.23522  1.000 29.58759  ? 162 LEU D O   1 
ATOM   1209 C  CB  . LEU A 1 182 ? -9.29993  -32.06043 28.12269  1.000 35.93426  ? 162 LEU D CB  1 
ATOM   1210 C  CG  . LEU A 1 182 ? -10.25255 -32.54240 29.21945  1.000 41.76642  ? 162 LEU D CG  1 
ATOM   1211 C  CD1 . LEU A 1 182 ? -10.62685 -31.39203 30.14842  1.000 25.42909  ? 162 LEU D CD1 1 
ATOM   1212 C  CD2 . LEU A 1 182 ? -11.49634 -33.17486 28.61546  1.000 31.92352  ? 162 LEU D CD2 1 
ATOM   1213 N  N   . SER A 1 183 ? -8.57818  -31.92521 24.95542  1.000 39.68392  ? 163 SER D N   1 
ATOM   1214 C  CA  . SER A 1 183 ? -7.93256  -31.04972 23.98999  1.000 46.41243  ? 163 SER D CA  1 
ATOM   1215 C  C   . SER A 1 183 ? -8.60683  -29.68737 24.07016  1.000 39.73326  ? 163 SER D C   1 
ATOM   1216 O  O   . SER A 1 183 ? -9.83932  -29.60412 24.08837  1.000 44.71037  ? 163 SER D O   1 
ATOM   1217 C  CB  . SER A 1 183 ? -8.02380  -31.62671 22.57456  1.000 39.30348  ? 163 SER D CB  1 
ATOM   1218 O  OG  . SER A 1 183 ? -7.38116  -30.78380 21.63440  1.000 62.66441  ? 163 SER D OG  1 
ATOM   1219 N  N   . ASP A 1 184 ? -7.80277  -28.62693 24.13710  1.000 38.86405  ? 164 ASP D N   1 
ATOM   1220 C  CA  . ASP A 1 184 ? -8.32862  -27.28542 24.36401  1.000 43.28873  ? 164 ASP D CA  1 
ATOM   1221 C  C   . ASP A 1 184 ? -8.90395  -26.64016 23.10877  1.000 46.06738  ? 164 ASP D C   1 
ATOM   1222 O  O   . ASP A 1 184 ? -9.38591  -25.50498 23.18639  1.000 43.89177  ? 164 ASP D O   1 
ATOM   1223 C  CB  . ASP A 1 184 ? -7.23777  -26.38240 24.95037  1.000 37.90101  ? 164 ASP D CB  1 
ATOM   1224 C  CG  . ASP A 1 184 ? -6.18326  -25.97997 23.92500  1.000 45.18379  ? 164 ASP D CG  1 
ATOM   1225 O  OD1 . ASP A 1 184 ? -6.04133  -26.65778 22.88271  1.000 42.49678  ? 164 ASP D OD1 1 
ATOM   1226 O  OD2 . ASP A 1 184 ? -5.47993  -24.97817 24.17490  1.000 51.22420  ? 164 ASP D OD2 1 
ATOM   1227 N  N   . GLY A 1 185 ? -8.85969  -27.32154 21.96368  1.000 39.71764  ? 165 GLY D N   1 
ATOM   1228 C  CA  . GLY A 1 185 ? -9.34484  -26.77041 20.72052  1.000 45.19792  ? 165 GLY D CA  1 
ATOM   1229 C  C   . GLY A 1 185 ? -8.28924  -26.11325 19.86136  1.000 46.63292  ? 165 GLY D C   1 
ATOM   1230 O  O   . GLY A 1 185 ? -8.60011  -25.69785 18.73742  1.000 44.87375  ? 165 GLY D O   1 
ATOM   1231 N  N   . GLN A 1 186 ? -7.05348  -26.01354 20.34811  1.000 48.23870  ? 166 GLN D N   1 
ATOM   1232 C  CA  . GLN A 1 186 ? -5.95484  -25.36195 19.64527  1.000 47.76486  ? 166 GLN D CA  1 
ATOM   1233 C  C   . GLN A 1 186 ? -4.68192  -26.18087 19.76873  1.000 45.29517  ? 166 GLN D C   1 
ATOM   1234 O  O   . GLN A 1 186 ? -3.57204  -25.63878 19.83868  1.000 49.43560  ? 166 GLN D O   1 
ATOM   1235 C  CB  . GLN A 1 186 ? -5.74559  -23.94129 20.16066  1.000 44.85525  ? 166 GLN D CB  1 
ATOM   1236 C  CG  . GLN A 1 186 ? -6.89395  -22.99990 19.83475  1.000 48.99744  ? 166 GLN D CG  1 
ATOM   1237 C  CD  . GLN A 1 186 ? -6.83468  -21.69829 20.61468  1.000 54.71242  ? 166 GLN D CD  1 
ATOM   1238 O  OE1 . GLN A 1 186 ? -5.93118  -21.48960 21.42221  1.000 61.91412  ? 166 GLN D OE1 1 
ATOM   1239 N  NE2 . GLN A 1 186 ? -7.80411  -20.81676 20.37812  1.000 37.38383  ? 166 GLN D NE2 1 
ATOM   1240 N  N   . GLY A 1 187 ? -4.83726  -27.50417 19.80646  1.000 43.17468  ? 167 GLY D N   1 
ATOM   1241 C  CA  . GLY A 1 187 ? -3.71398  -28.42115 19.74741  1.000 41.86624  ? 167 GLY D CA  1 
ATOM   1242 C  C   . GLY A 1 187 ? -3.02870  -28.72284 21.06114  1.000 41.67645  ? 167 GLY D C   1 
ATOM   1243 O  O   . GLY A 1 187 ? -1.96448  -29.35439 21.05160  1.000 52.34582  ? 167 GLY D O   1 
ATOM   1244 N  N   . ARG A 1 188 ? -3.58924  -28.29205 22.18681  1.000 40.55286  ? 168 ARG D N   1 
ATOM   1245 C  CA  . ARG A 1 188 ? -2.99568  -28.52701 23.49651  1.000 40.20018  ? 168 ARG D CA  1 
ATOM   1246 C  C   . ARG A 1 188 ? -3.79377  -29.58512 24.24556  1.000 38.06958  ? 168 ARG D C   1 
ATOM   1247 O  O   . ARG A 1 188 ? -5.00964  -29.44736 24.42111  1.000 39.09333  ? 168 ARG D O   1 
ATOM   1248 C  CB  . ARG A 1 188 ? -2.93321  -27.23398 24.31307  1.000 40.70413  ? 168 ARG D CB  1 
ATOM   1249 C  CG  . ARG A 1 188 ? -1.72781  -26.36797 24.00356  1.000 53.07968  ? 168 ARG D CG  1 
ATOM   1250 C  CD  . ARG A 1 188 ? -2.02592  -24.89881 24.23969  1.000 65.82194  ? 168 ARG D CD  1 
ATOM   1251 N  NE  . ARG A 1 188 ? -0.82965  -24.07697 24.10314  1.000 62.52524  ? 168 ARG D NE  1 
ATOM   1252 C  CZ  . ARG A 1 188 ? -0.81678  -22.85388 23.59143  1.000 73.49341  ? 168 ARG D CZ  1 
ATOM   1253 N  NH1 . ARG A 1 188 ? -1.91729  -22.29007 23.11947  1.000 77.42318  ? 168 ARG D NH1 1 
ATOM   1254 N  NH2 . ARG A 1 188 ? 0.33090   -22.18405 23.54111  1.000 68.06557  ? 168 ARG D NH2 1 
ATOM   1255 N  N   . ARG A 1 189 ? -3.10579  -30.63044 24.69042  1.000 39.50648  ? 169 ARG D N   1 
ATOM   1256 C  CA  . ARG A 1 189 ? -3.71059  -31.70128 25.46565  1.000 31.57999  ? 169 ARG D CA  1 
ATOM   1257 C  C   . ARG A 1 189 ? -3.42857  -31.49827 26.94970  1.000 34.15478  ? 169 ARG D C   1 
ATOM   1258 O  O   . ARG A 1 189 ? -2.37527  -30.98438 27.33283  1.000 37.57463  ? 169 ARG D O   1 
ATOM   1259 C  CB  . ARG A 1 189 ? -3.17846  -33.06376 25.01688  1.000 33.70768  ? 169 ARG D CB  1 
ATOM   1260 C  CG  . ARG A 1 189 ? -3.45928  -33.40289 23.55759  1.000 37.51349  ? 169 ARG D CG  1 
ATOM   1261 C  CD  . ARG A 1 189 ? -2.70080  -34.65521 23.14808  1.000 40.05194  ? 169 ARG D CD  1 
ATOM   1262 N  NE  . ARG A 1 189 ? -3.14725  -35.82002 23.90217  1.000 50.34915  ? 169 ARG D NE  1 
ATOM   1263 C  CZ  . ARG A 1 189 ? -2.42378  -36.91455 24.09597  1.000 52.30525  ? 169 ARG D CZ  1 
ATOM   1264 N  NH1 . ARG A 1 189 ? -1.18795  -37.01831 23.63447  1.000 47.13218  ? 169 ARG D NH1 1 
ATOM   1265 N  NH2 . ARG A 1 189 ? -2.95154  -37.92849 24.77611  1.000 45.83614  ? 169 ARG D NH2 1 
ATOM   1266 N  N   . ARG A 1 190 ? -4.38451  -31.90057 27.78665  1.000 34.22044  ? 170 ARG D N   1 
ATOM   1267 C  CA  . ARG A 1 190 ? -4.20799  -31.80723 29.22893  1.000 28.05129  ? 170 ARG D CA  1 
ATOM   1268 C  C   . ARG A 1 190 ? -4.97758  -32.93045 29.90919  1.000 29.85619  ? 170 ARG D C   1 
ATOM   1269 O  O   . ARG A 1 190 ? -5.99480  -33.40915 29.39870  1.000 26.77566  ? 170 ARG D O   1 
ATOM   1270 C  CB  . ARG A 1 190 ? -4.65316  -30.44182 29.77379  1.000 28.18962  ? 170 ARG D CB  1 
ATOM   1271 C  CG  . ARG A 1 190 ? -6.14537  -30.17088 29.69681  1.000 31.34150  ? 170 ARG D CG  1 
ATOM   1272 C  CD  . ARG A 1 190 ? -6.44095  -28.74361 30.13474  1.000 34.84490  ? 170 ARG D CD  1 
ATOM   1273 N  NE  . ARG A 1 190 ? -7.85685  -28.51374 30.39520  1.000 35.41331  ? 170 ARG D NE  1 
ATOM   1274 C  CZ  . ARG A 1 190 ? -8.72151  -28.06001 29.49869  1.000 33.51788  ? 170 ARG D CZ  1 
ATOM   1275 N  NH1 . ARG A 1 190 ? -8.35413  -27.79603 28.25513  1.000 31.02875  ? 170 ARG D NH1 1 
ATOM   1276 N  NH2 . ARG A 1 190 ? -9.98640  -27.86467 29.85952  1.000 33.34815  ? 170 ARG D NH2 1 
ATOM   1277 N  N   . VAL A 1 191 ? -4.46540  -33.35609 31.06480  1.000 23.75015  ? 171 VAL D N   1 
ATOM   1278 C  CA  . VAL A 1 191 ? -5.07309  -34.40674 31.86689  1.000 27.92364  ? 171 VAL D CA  1 
ATOM   1279 C  C   . VAL A 1 191 ? -5.11847  -33.93436 33.31363  1.000 30.34580  ? 171 VAL D C   1 
ATOM   1280 O  O   . VAL A 1 191 ? -4.36094  -33.05499 33.73206  1.000 26.94345  ? 171 VAL D O   1 
ATOM   1281 C  CB  . VAL A 1 191 ? -4.31361  -35.75198 31.75594  1.000 28.43090  ? 171 VAL D CB  1 
ATOM   1282 C  CG1 . VAL A 1 191 ? -4.37684  -36.28869 30.33020  1.000 26.67380  ? 171 VAL D CG1 1 
ATOM   1283 C  CG2 . VAL A 1 191 ? -2.86848  -35.59024 32.20070  1.000 22.27685  ? 171 VAL D CG2 1 
ATOM   1284 N  N   . HIS A 1 192 ? -6.03271  -34.52489 34.07660  1.000 32.00697  ? 172 HIS D N   1 
ATOM   1285 C  CA  . HIS A 1 192 ? -6.24614  -34.16378 35.47173  1.000 30.84664  ? 172 HIS D CA  1 
ATOM   1286 C  C   . HIS A 1 192 ? -5.83818  -35.33738 36.35261  1.000 34.70924  ? 172 HIS D C   1 
ATOM   1287 O  O   . HIS A 1 192 ? -6.42564  -36.42167 36.26216  1.000 33.66321  ? 172 HIS D O   1 
ATOM   1288 C  CB  . HIS A 1 192 ? -7.70206  -33.76270 35.70866  1.000 34.34405  ? 172 HIS D CB  1 
ATOM   1289 C  CG  . HIS A 1 192 ? -8.11529  -32.54498 34.94140  1.000 41.29745  ? 172 HIS D CG  1 
ATOM   1290 N  ND1 . HIS A 1 192 ? -9.01643  -32.59050 33.89840  1.000 42.43617  ? 172 HIS D ND1 1 
ATOM   1291 C  CD2 . HIS A 1 192 ? -7.72716  -31.25157 35.04772  1.000 37.27436  ? 172 HIS D CD2 1 
ATOM   1292 C  CE1 . HIS A 1 192 ? -9.17585  -31.37557 33.40456  1.000 36.83438  ? 172 HIS D CE1 1 
ATOM   1293 N  NE2 . HIS A 1 192 ? -8.40422  -30.54518 34.08331  1.000 42.42834  ? 172 HIS D NE2 1 
ATOM   1294 N  N   . LEU A 1 193 ? -4.82812  -35.12053 37.19167  1.000 31.49406  ? 173 LEU D N   1 
ATOM   1295 C  CA  . LEU A 1 193 ? -4.23003  -36.16175 38.00947  1.000 31.00313  ? 173 LEU D CA  1 
ATOM   1296 C  C   . LEU A 1 193 ? -4.55427  -35.93145 39.47897  1.000 30.92012  ? 173 LEU D C   1 
ATOM   1297 O  O   . LEU A 1 193 ? -4.71571  -34.79231 39.92993  1.000 33.41456  ? 173 LEU D O   1 
ATOM   1298 C  CB  . LEU A 1 193 ? -2.71090  -36.20156 37.81321  1.000 26.45795  ? 173 LEU D CB  1 
ATOM   1299 C  CG  . LEU A 1 193 ? -2.23912  -36.19343 36.35666  1.000 34.03115  ? 173 LEU D CG  1 
ATOM   1300 C  CD1 . LEU A 1 193 ? -0.72114  -36.18466 36.27985  1.000 21.66940  ? 173 LEU D CD1 1 
ATOM   1301 C  CD2 . LEU A 1 193 ? -2.81774  -37.37566 35.58537  1.000 28.06024  ? 173 LEU D CD2 1 
ATOM   1302 N  N   . HIS A 1 194 ? -4.61775  -37.03279 40.22199  1.000 31.42568  ? 174 HIS D N   1 
ATOM   1303 C  CA  . HIS A 1 194 ? -5.00744  -37.03289 41.62362  1.000 31.06047  ? 174 HIS D CA  1 
ATOM   1304 C  C   . HIS A 1 194 ? -4.11805  -38.01144 42.37212  1.000 36.41431  ? 174 HIS D C   1 
ATOM   1305 O  O   . HIS A 1 194 ? -3.96153  -39.15924 41.94422  1.000 32.17068  ? 174 HIS D O   1 
ATOM   1306 C  CB  . HIS A 1 194 ? -6.48687  -37.42132 41.76541  1.000 37.43527  ? 174 HIS D CB  1 
ATOM   1307 C  CG  . HIS A 1 194 ? -6.91464  -37.73074 43.16816  1.000 46.57046  ? 174 HIS D CG  1 
ATOM   1308 N  ND1 . HIS A 1 194 ? -6.55846  -38.89311 43.81986  1.000 45.40564  ? 174 HIS D ND1 1 
ATOM   1309 C  CD2 . HIS A 1 194 ? -7.70492  -37.04585 44.02850  1.000 41.56937  ? 174 HIS D CD2 1 
ATOM   1310 C  CE1 . HIS A 1 194 ? -7.09025  -38.89887 45.02886  1.000 37.96999  ? 174 HIS D CE1 1 
ATOM   1311 N  NE2 . HIS A 1 194 ? -7.79377  -37.79132 45.17896  1.000 37.59234  ? 174 HIS D NE2 1 
ATOM   1312 N  N   . LYS A 1 195 ? -3.53252  -37.56372 43.47884  1.000 33.72466  ? 175 LYS D N   1 
ATOM   1313 C  CA  . LYS A 1 195 ? -2.75294  -38.43518 44.34507  1.000 35.49215  ? 175 LYS D CA  1 
ATOM   1314 C  C   . LYS A 1 195 ? -3.34066  -38.40278 45.74734  1.000 39.03490  ? 175 LYS D C   1 
ATOM   1315 O  O   . LYS A 1 195 ? -3.50730  -37.32721 46.33055  1.000 33.62979  ? 175 LYS D O   1 
ATOM   1316 C  CB  . LYS A 1 195 ? -1.27677  -38.02785 44.38692  1.000 33.26841  ? 175 LYS D CB  1 
ATOM   1317 C  CG  . LYS A 1 195 ? -0.47546  -38.85161 45.38590  1.000 37.88812  ? 175 LYS D CG  1 
ATOM   1318 C  CD  . LYS A 1 195 ? 0.98390   -38.44222 45.45319  1.000 34.44802  ? 175 LYS D CD  1 
ATOM   1319 C  CE  . LYS A 1 195 ? 1.71730   -39.23293 46.53642  1.000 40.82121  ? 175 LYS D CE  1 
ATOM   1320 N  NZ  . LYS A 1 195 ? 1.65847   -40.70734 46.31579  1.000 44.17154  ? 175 LYS D NZ  1 
ATOM   1321 N  N   . SER A 1 196 ? -3.65680  -39.57832 46.28114  1.000 42.15139  ? 176 SER D N   1 
ATOM   1322 C  CA  . SER A 1 196 ? -4.12466  -39.66910 47.65465  1.000 42.80661  ? 176 SER D CA  1 
ATOM   1323 C  C   . SER A 1 196 ? -2.98543  -39.35628 48.61678  1.000 45.39017  ? 176 SER D C   1 
ATOM   1324 O  O   . SER A 1 196 ? -1.82600  -39.70201 48.37078  1.000 47.82409  ? 176 SER D O   1 
ATOM   1325 C  CB  . SER A 1 196 ? -4.68746  -41.06289 47.93540  1.000 37.85410  ? 176 SER D CB  1 
ATOM   1326 O  OG  . SER A 1 196 ? -5.73462  -41.38828 47.03699  1.000 55.96692  ? 176 SER D OG  1 
ATOM   1327 N  N   . LEU A 1 197 ? -3.31981  -38.69191 49.71665  1.000 46.74179  ? 177 LEU D N   1 
ATOM   1328 C  CA  . LEU A 1 197 ? -2.32701  -38.36030 50.73312  1.000 47.77503  ? 177 LEU D CA  1 
ATOM   1329 C  C   . LEU A 1 197 ? -2.55823  -39.15955 52.00999  1.000 53.21857  ? 177 LEU D C   1 
ATOM   1330 O  O   . LEU A 1 197 ? -3.66572  -39.62946 52.27307  1.000 49.20733  ? 177 LEU D O   1 
ATOM   1331 C  CB  . LEU A 1 197 ? -2.35362  -36.86536 51.04237  1.000 46.82455  ? 177 LEU D CB  1 
ATOM   1332 C  CG  . LEU A 1 197 ? -1.96501  -35.92667 49.89852  1.000 51.60406  ? 177 LEU D CG  1 
ATOM   1333 C  CD1 . LEU A 1 197 ? -2.05026  -34.47486 50.34548  1.000 41.39743  ? 177 LEU D CD1 1 
ATOM   1334 C  CD2 . LEU A 1 197 ? -0.57243  -36.25511 49.37091  1.000 35.71672  ? 177 LEU D CD2 1 
ATOM   1335 N  N   . ALA B 1 34  ? -29.35805 5.88835   16.23569  1.000 51.36675  ? 14  ALA A N   1 
ATOM   1336 C  CA  . ALA B 1 34  ? -29.33467 5.55884   17.65565  1.000 55.97838  ? 14  ALA A CA  1 
ATOM   1337 C  C   . ALA B 1 34  ? -27.93080 5.71558   18.23396  1.000 61.41033  ? 14  ALA A C   1 
ATOM   1338 O  O   . ALA B 1 34  ? -27.69244 6.57371   19.08352  1.000 62.48406  ? 14  ALA A O   1 
ATOM   1339 C  CB  . ALA B 1 34  ? -29.84329 4.14523   17.87999  1.000 48.90541  ? 14  ALA A CB  1 
ATOM   1340 N  N   . TRP B 1 35  ? -27.00747 4.87517   17.77345  1.000 53.00660  ? 15  TRP A N   1 
ATOM   1341 C  CA  . TRP B 1 35  ? -25.61502 4.91621   18.20227  1.000 51.62005  ? 15  TRP A CA  1 
ATOM   1342 C  C   . TRP B 1 35  ? -24.78718 5.58640   17.11421  1.000 54.24444  ? 15  TRP A C   1 
ATOM   1343 O  O   . TRP B 1 35  ? -24.68605 5.06434   15.99700  1.000 57.54723  ? 15  TRP A O   1 
ATOM   1344 C  CB  . TRP B 1 35  ? -25.08830 3.50964   18.48883  1.000 46.22246  ? 15  TRP A CB  1 
ATOM   1345 C  CG  . TRP B 1 35  ? -25.85435 2.78828   19.54988  1.000 48.98704  ? 15  TRP A CG  1 
ATOM   1346 C  CD1 . TRP B 1 35  ? -26.95096 1.99717   19.37201  1.000 43.09431  ? 15  TRP A CD1 1 
ATOM   1347 C  CD2 . TRP B 1 35  ? -25.58870 2.79594   20.95921  1.000 50.99380  ? 15  TRP A CD2 1 
ATOM   1348 N  NE1 . TRP B 1 35  ? -27.38347 1.50997   20.58090  1.000 49.18747  ? 15  TRP A NE1 1 
ATOM   1349 C  CE2 . TRP B 1 35  ? -26.56473 1.98540   21.57125  1.000 45.39214  ? 15  TRP A CE2 1 
ATOM   1350 C  CE3 . TRP B 1 35  ? -24.62037 3.40805   21.76154  1.000 46.19409  ? 15  TRP A CE3 1 
ATOM   1351 C  CZ2 . TRP B 1 35  ? -26.60081 1.76968   22.94714  1.000 44.74040  ? 15  TRP A CZ2 1 
ATOM   1352 C  CZ3 . TRP B 1 35  ? -24.65776 3.19300   23.12838  1.000 38.68354  ? 15  TRP A CZ3 1 
ATOM   1353 C  CH2 . TRP B 1 35  ? -25.64102 2.38055   23.70689  1.000 53.45468  ? 15  TRP A CH2 1 
ATOM   1354 N  N   . GLN B 1 36  ? -24.19483 6.73381   17.43993  1.000 39.98722  ? 16  GLN A N   1 
ATOM   1355 C  CA  . GLN B 1 36  ? -23.44699 7.52460   16.47116  1.000 43.81694  ? 16  GLN A CA  1 
ATOM   1356 C  C   . GLN B 1 36  ? -22.04446 7.79158   16.99464  1.000 47.03208  ? 16  GLN A C   1 
ATOM   1357 O  O   . GLN B 1 36  ? -21.88053 8.31563   18.10049  1.000 41.26610  ? 16  GLN A O   1 
ATOM   1358 C  CB  . GLN B 1 36  ? -24.15025 8.85487   16.18117  1.000 52.97752  ? 16  GLN A CB  1 
ATOM   1359 C  CG  . GLN B 1 36  ? -25.65611 8.75797   15.99270  1.000 56.49236  ? 16  GLN A CG  1 
ATOM   1360 C  CD  . GLN B 1 36  ? -26.05262 8.00942   14.73261  1.000 70.57665  ? 16  GLN A CD  1 
ATOM   1361 O  OE1 . GLN B 1 36  ? -25.24788 7.83864   13.81447  1.000 60.41664  ? 16  GLN A OE1 1 
ATOM   1362 N  NE2 . GLN B 1 36  ? -27.30232 7.55838   14.68340  1.000 70.98103  ? 16  GLN A NE2 1 
ATOM   1363 N  N   . TRP B 1 37  ? -21.03943 7.44515   16.19967  1.000 40.70921  ? 17  TRP A N   1 
ATOM   1364 C  CA  . TRP B 1 37  ? -19.65834 7.75805   16.52865  1.000 41.95941  ? 17  TRP A CA  1 
ATOM   1365 C  C   . TRP B 1 37  ? -19.24758 9.06737   15.86788  1.000 46.52095  ? 17  TRP A C   1 
ATOM   1366 O  O   . TRP B 1 37  ? -19.70691 9.40483   14.77303  1.000 60.85134  ? 17  TRP A O   1 
ATOM   1367 C  CB  . TRP B 1 37  ? -18.71440 6.63674   16.09500  1.000 39.56146  ? 17  TRP A CB  1 
ATOM   1368 C  CG  . TRP B 1 37  ? -18.63863 5.49852   17.06827  1.000 39.59071  ? 17  TRP A CG  1 
ATOM   1369 C  CD1 . TRP B 1 37  ? -19.25967 4.28833   16.96351  1.000 31.58095  ? 17  TRP A CD1 1 
ATOM   1370 C  CD2 . TRP B 1 37  ? -17.89447 5.46321   18.29338  1.000 41.52270  ? 17  TRP A CD2 1 
ATOM   1371 N  NE1 . TRP B 1 37  ? -18.94976 3.50140   18.04596  1.000 38.84170  ? 17  TRP A NE1 1 
ATOM   1372 C  CE2 . TRP B 1 37  ? -18.11328 4.19911   18.87756  1.000 39.00804  ? 17  TRP A CE2 1 
ATOM   1373 C  CE3 . TRP B 1 37  ? -17.06427 6.37729   18.95259  1.000 38.05732  ? 17  TRP A CE3 1 
ATOM   1374 C  CZ2 . TRP B 1 37  ? -17.53561 3.82680   20.09093  1.000 32.88684  ? 17  TRP A CZ2 1 
ATOM   1375 C  CZ3 . TRP B 1 37  ? -16.48874 6.00460   20.15653  1.000 26.00495  ? 17  TRP A CZ3 1 
ATOM   1376 C  CH2 . TRP B 1 37  ? -16.72704 4.74071   20.71212  1.000 31.39189  ? 17  TRP A CH2 1 
ATOM   1377 N  N   . GLU B 1 38  ? -18.37519 9.80556   16.55121  1.000 47.34246  ? 18  GLU A N   1 
ATOM   1378 C  CA  . GLU B 1 38  ? -17.88375 11.07375  16.03833  1.000 37.53778  ? 18  GLU A CA  1 
ATOM   1379 C  C   . GLU B 1 38  ? -16.48270 11.31146  16.57663  1.000 42.94176  ? 18  GLU A C   1 
ATOM   1380 O  O   . GLU B 1 38  ? -16.06448 10.70628  17.56774  1.000 41.47517  ? 18  GLU A O   1 
ATOM   1381 C  CB  . GLU B 1 38  ? -18.80929 12.23491  16.43049  1.000 45.56701  ? 18  GLU A CB  1 
ATOM   1382 C  CG  . GLU B 1 38  ? -18.73140 12.60793  17.90294  1.000 41.80496  ? 18  GLU A CG  1 
ATOM   1383 C  CD  . GLU B 1 38  ? -19.79339 13.60535  18.31918  1.000 42.31077  ? 18  GLU A CD  1 
ATOM   1384 O  OE1 . GLU B 1 38  ? -20.97467 13.40068  17.97130  1.000 55.32066  ? 18  GLU A OE1 1 
ATOM   1385 O  OE2 . GLU B 1 38  ? -19.44715 14.59543  18.99715  1.000 45.64265  ? 18  GLU A OE2 1 
ATOM   1386 N  N   . VAL B 1 39  ? -15.75278 12.18765  15.89581  1.000 41.98908  ? 19  VAL A N   1 
ATOM   1387 C  CA  . VAL B 1 39  ? -14.52341 12.75418  16.43691  1.000 37.42491  ? 19  VAL A CA  1 
ATOM   1388 C  C   . VAL B 1 39  ? -14.91184 13.99226  17.23112  1.000 43.97205  ? 19  VAL A C   1 
ATOM   1389 O  O   . VAL B 1 39  ? -15.41972 14.96617  16.66641  1.000 38.66795  ? 19  VAL A O   1 
ATOM   1390 C  CB  . VAL B 1 39  ? -13.51913 13.09490  15.32591  1.000 38.92152  ? 19  VAL A CB  1 
ATOM   1391 C  CG1 . VAL B 1 39  ? -12.28463 13.77805  15.90734  1.000 36.75719  ? 19  VAL A CG1 1 
ATOM   1392 C  CG2 . VAL B 1 39  ? -13.12775 11.83422  14.56587  1.000 33.09329  ? 19  VAL A CG2 1 
ATOM   1393 N  N   . SER B 1 40  ? -14.69020 13.95059  18.54005  1.000 36.63723  ? 20  SER A N   1 
ATOM   1394 C  CA  . SER B 1 40  ? -15.19203 15.00254  19.41021  1.000 39.88417  ? 20  SER A CA  1 
ATOM   1395 C  C   . SER B 1 40  ? -14.45383 16.31278  19.17186  1.000 33.15272  ? 20  SER A C   1 
ATOM   1396 O  O   . SER B 1 40  ? -13.25258 16.33100  18.89095  1.000 37.43589  ? 20  SER A O   1 
ATOM   1397 C  CB  . SER B 1 40  ? -15.05871 14.58967  20.87397  1.000 40.60194  ? 20  SER A CB  1 
ATOM   1398 O  OG  . SER B 1 40  ? -15.58447 15.59489  21.72302  1.000 48.49714  ? 20  SER A OG  1 
ATOM   1399 N  N   . ARG B 1 41  ? -15.19108 17.41735  19.28271  1.000 41.44727  ? 21  ARG A N   1 
ATOM   1400 C  CA  . ARG B 1 41  ? -14.61041 18.75129  19.23374  1.000 54.15823  ? 21  ARG A CA  1 
ATOM   1401 C  C   . ARG B 1 41  ? -15.04314 19.59454  20.42725  1.000 44.05918  ? 21  ARG A C   1 
ATOM   1402 O  O   . ARG B 1 41  ? -14.82565 20.81199  20.42342  1.000 49.23219  ? 21  ARG A O   1 
ATOM   1403 C  CB  . ARG B 1 41  ? -14.97876 19.45199  17.92027  1.000 40.41504  ? 21  ARG A CB  1 
ATOM   1404 C  CG  . ARG B 1 41  ? -16.45941 19.74543  17.76247  1.000 52.06595  ? 21  ARG A CG  1 
ATOM   1405 C  CD  . ARG B 1 41  ? -16.90276 19.54010  16.32309  1.000 55.23202  ? 21  ARG A CD  1 
ATOM   1406 N  NE  . ARG B 1 41  ? -18.06950 20.34431  15.97936  1.000 62.03832  ? 21  ARG A NE  1 
ATOM   1407 C  CZ  . ARG B 1 41  ? -19.32117 20.02017  16.27420  1.000 61.75515  ? 21  ARG A CZ  1 
ATOM   1408 N  NH1 . ARG B 1 41  ? -19.60975 18.92424  16.95708  1.000 62.98345  ? 21  ARG A NH1 1 
ATOM   1409 N  NH2 . ARG B 1 41  ? -20.30867 20.81693  15.87494  1.000 51.32253  ? 21  ARG A NH2 1 
ATOM   1410 N  N   . ASP B 1 42  ? -15.63420 18.97472  21.44969  1.000 44.13400  ? 22  ASP A N   1 
ATOM   1411 C  CA  . ASP B 1 42  ? -16.15788 19.66427  22.62518  1.000 49.38980  ? 22  ASP A CA  1 
ATOM   1412 C  C   . ASP B 1 42  ? -15.34371 19.24025  23.84252  1.000 41.56352  ? 22  ASP A C   1 
ATOM   1413 O  O   . ASP B 1 42  ? -15.46204 18.10256  24.30936  1.000 42.23834  ? 22  ASP A O   1 
ATOM   1414 C  CB  . ASP B 1 42  ? -17.64041 19.34842  22.81782  1.000 53.29747  ? 22  ASP A CB  1 
ATOM   1415 C  CG  . ASP B 1 42  ? -18.32396 20.31184  23.76379  1.000 62.06841  ? 22  ASP A CG  1 
ATOM   1416 O  OD1 . ASP B 1 42  ? -17.68045 21.30057  24.17442  1.000 68.99858  ? 22  ASP A OD1 1 
ATOM   1417 O  OD2 . ASP B 1 42  ? -19.50793 20.08445  24.09213  1.000 62.80175  ? 22  ASP A OD2 1 
ATOM   1418 N  N   . THR B 1 43  ? -14.53153 20.16132  24.36518  1.000 43.15429  ? 23  THR A N   1 
ATOM   1419 C  CA  . THR B 1 43  ? -13.64816 19.83142  25.48130  1.000 43.03727  ? 23  THR A CA  1 
ATOM   1420 C  C   . THR B 1 43  ? -14.42572 19.64066  26.77973  1.000 36.17418  ? 23  THR A C   1 
ATOM   1421 O  O   . THR B 1 43  ? -14.15827 18.69907  27.53907  1.000 34.10087  ? 23  THR A O   1 
ATOM   1422 C  CB  . THR B 1 43  ? -12.58859 20.92242  25.64828  1.000 30.97272  ? 23  THR A CB  1 
ATOM   1423 O  OG1 . THR B 1 43  ? -11.65130 20.84994  24.56665  1.000 43.80483  ? 23  THR A OG1 1 
ATOM   1424 C  CG2 . THR B 1 43  ? -11.84748 20.75323  26.96564  1.000 45.10194  ? 23  THR A CG2 1 
ATOM   1425 N  N   . GLY B 1 44  ? -15.38231 20.52781  27.05720  1.000 28.15353  ? 24  GLY A N   1 
ATOM   1426 C  CA  . GLY B 1 44  ? -16.14531 20.41320  28.28883  1.000 25.24868  ? 24  GLY A CA  1 
ATOM   1427 C  C   . GLY B 1 44  ? -16.94017 19.12450  28.36696  1.000 36.06958  ? 24  GLY A C   1 
ATOM   1428 O  O   . GLY B 1 44  ? -16.98203 18.47425  29.41292  1.000 37.48361  ? 24  GLY A O   1 
ATOM   1429 N  N   . GLU B 1 45  ? -17.57083 18.73297  27.25774  1.000 28.48962  ? 25  GLU A N   1 
ATOM   1430 C  CA  . GLU B 1 45  ? -18.34098 17.49235  27.22528  1.000 28.96203  ? 25  GLU A CA  1 
ATOM   1431 C  C   . GLU B 1 45  ? -17.45228 16.28540  27.51033  1.000 41.09143  ? 25  GLU A C   1 
ATOM   1432 O  O   . GLU B 1 45  ? -17.79341 15.42203  28.33407  1.000 36.66044  ? 25  GLU A O   1 
ATOM   1433 C  CB  . GLU B 1 45  ? -19.02377 17.36309  25.86314  1.000 32.97678  ? 25  GLU A CB  1 
ATOM   1434 C  CG  . GLU B 1 45  ? -20.01851 16.22842  25.72185  1.000 46.62253  ? 25  GLU A CG  1 
ATOM   1435 C  CD  . GLU B 1 45  ? -20.77511 16.30661  24.40768  1.000 55.03279  ? 25  GLU A CD  1 
ATOM   1436 O  OE1 . GLU B 1 45  ? -20.12660 16.50220  23.35778  1.000 45.25475  ? 25  GLU A OE1 1 
ATOM   1437 O  OE2 . GLU B 1 45  ? -22.01941 16.20286  24.42492  1.000 54.79890  ? 25  GLU A OE2 1 
ATOM   1438 N  N   . VAL B 1 46  ? -16.29757 16.22303  26.84101  1.000 34.76124  ? 26  VAL A N   1 
ATOM   1439 C  CA  . VAL B 1 46  ? -15.36847 15.11188  27.01865  1.000 36.53215  ? 26  VAL A CA  1 
ATOM   1440 C  C   . VAL B 1 46  ? -14.89024 15.04029  28.46316  1.000 36.49302  ? 26  VAL A C   1 
ATOM   1441 O  O   . VAL B 1 46  ? -14.91223 13.97332  29.08966  1.000 27.12099  ? 26  VAL A O   1 
ATOM   1442 C  CB  . VAL B 1 46  ? -14.18820 15.24880  26.04033  1.000 36.70047  ? 26  VAL A CB  1 
ATOM   1443 C  CG1 . VAL B 1 46  ? -13.03623 14.35731  26.47814  1.000 32.93743  ? 26  VAL A CG1 1 
ATOM   1444 C  CG2 . VAL B 1 46  ? -14.62495 14.90354  24.63271  1.000 30.98365  ? 26  VAL A CG2 1 
ATOM   1445 N  N   . HIS B 1 47  ? -14.43447 16.17292  29.00738  1.000 34.35846  ? 27  HIS A N   1 
ATOM   1446 C  CA  . HIS B 1 47  ? -13.91298 16.17436  30.36991  1.000 32.05337  ? 27  HIS A CA  1 
ATOM   1447 C  C   . HIS B 1 47  ? -14.99593 15.80726  31.37210  1.000 32.28555  ? 27  HIS A C   1 
ATOM   1448 O  O   . HIS B 1 47  ? -14.73117 15.09474  32.34851  1.000 30.89234  ? 27  HIS A O   1 
ATOM   1449 C  CB  . HIS B 1 47  ? -13.32147 17.54115  30.70747  1.000 28.79636  ? 27  HIS A CB  1 
ATOM   1450 C  CG  . HIS B 1 47  ? -12.32251 17.50752  31.82205  1.000 36.93610  ? 27  HIS A CG  1 
ATOM   1451 N  ND1 . HIS B 1 47  ? -11.02087 17.09141  31.63800  1.000 33.24924  ? 27  HIS A ND1 1 
ATOM   1452 C  CD2 . HIS B 1 47  ? -12.43350 17.82973  33.13319  1.000 29.46442  ? 27  HIS A CD2 1 
ATOM   1453 C  CE1 . HIS B 1 47  ? -10.37118 17.16472  32.78585  1.000 29.51679  ? 27  HIS A CE1 1 
ATOM   1454 N  NE2 . HIS B 1 47  ? -11.20536 17.60937  33.70906  1.000 31.83188  ? 27  HIS A NE2 1 
ATOM   1455 N  N   . ALA B 1 48  ? -16.22525 16.27961  31.14581  1.000 26.00800  ? 28  ALA A N   1 
ATOM   1456 C  CA  . ALA B 1 48  ? -17.31204 15.97925  32.06727  1.000 27.52712  ? 28  ALA A CA  1 
ATOM   1457 C  C   . ALA B 1 48  ? -17.62411 14.49076  32.07422  1.000 30.33594  ? 28  ALA A C   1 
ATOM   1458 O  O   . ALA B 1 48  ? -17.79529 13.88840  33.14147  1.000 32.75786  ? 28  ALA A O   1 
ATOM   1459 C  CB  . ALA B 1 48  ? -18.55368 16.79152  31.69664  1.000 29.76746  ? 28  ALA A CB  1 
ATOM   1460 N  N   . MET B 1 49  ? -17.71506 13.87917  30.88928  1.000 27.05616  ? 29  MET A N   1 
ATOM   1461 C  CA  . MET B 1 49  ? -17.98947 12.44708  30.84341  1.000 29.56533  ? 29  MET A CA  1 
ATOM   1462 C  C   . MET B 1 49  ? -16.84480 11.64818  31.45779  1.000 31.94324  ? 29  MET A C   1 
ATOM   1463 O  O   . MET B 1 49  ? -17.07856 10.66577  32.17473  1.000 27.18576  ? 29  MET A O   1 
ATOM   1464 C  CB  . MET B 1 49  ? -18.25139 11.99456  29.40783  1.000 34.25065  ? 29  MET A CB  1 
ATOM   1465 C  CG  . MET B 1 49  ? -18.72027 10.54975  29.33539  1.000 32.75927  ? 29  MET A CG  1 
ATOM   1466 S  SD  . MET B 1 49  ? -17.90225 9.60457   28.04595  1.000 69.67411  ? 29  MET A SD  1 
ATOM   1467 C  CE  . MET B 1 49  ? -18.53167 10.39844  26.57518  1.000 48.16570  ? 29  MET A CE  1 
ATOM   1468 N  N   . LEU B 1 50  ? -15.60006 12.05769  31.19020  1.000 27.91097  ? 30  LEU A N   1 
ATOM   1469 C  CA  . LEU B 1 50  ? -14.44568 11.37651  31.76842  1.000 23.13467  ? 30  LEU A CA  1 
ATOM   1470 C  C   . LEU B 1 50  ? -14.48908 11.41822  33.29037  1.000 31.85003  ? 30  LEU A C   1 
ATOM   1471 O  O   . LEU B 1 50  ? -14.29127 10.39637  33.95774  1.000 25.45002  ? 30  LEU A O   1 
ATOM   1472 C  CB  . LEU B 1 50  ? -13.15374 12.01073  31.25168  1.000 26.40771  ? 30  LEU A CB  1 
ATOM   1473 C  CG  . LEU B 1 50  ? -11.83205 11.44084  31.77441  1.000 29.84228  ? 30  LEU A CG  1 
ATOM   1474 C  CD1 . LEU B 1 50  ? -11.69145 9.97208   31.40042  1.000 27.01783  ? 30  LEU A CD1 1 
ATOM   1475 C  CD2 . LEU B 1 50  ? -10.65452 12.24803  31.24668  1.000 27.64991  ? 30  LEU A CD2 1 
ATOM   1476 N  N   . CYS B 1 51  ? -14.75468 12.59650  33.85987  1.000 30.57044  ? 31  CYS A N   1 
ATOM   1477 C  CA  . CYS B 1 51  ? -14.79481 12.70981  35.31291  1.000 33.32497  ? 31  CYS A CA  1 
ATOM   1478 C  C   . CYS B 1 51  ? -15.98719 11.96961  35.90651  1.000 34.94513  ? 31  CYS A C   1 
ATOM   1479 O  O   . CYS B 1 51  ? -15.87379 11.39930  36.99631  1.000 32.93516  ? 31  CYS A O   1 
ATOM   1480 C  CB  . CYS B 1 51  ? -14.80885 14.18159  35.72383  1.000 29.88887  ? 31  CYS A CB  1 
ATOM   1481 S  SG  . CYS B 1 51  ? -13.29562 15.05892  35.27461  1.000 36.48557  ? 31  CYS A SG  1 
ATOM   1482 N  N   . ALA B 1 52  ? -17.12831 11.94897  35.21166  1.000 24.54905  ? 32  ALA A N   1 
ATOM   1483 C  CA  . ALA B 1 52  ? -18.27174 11.19516  35.71802  1.000 26.40286  ? 32  ALA A CA  1 
ATOM   1484 C  C   . ALA B 1 52  ? -17.97328 9.69955   35.74760  1.000 36.00139  ? 32  ALA A C   1 
ATOM   1485 O  O   . ALA B 1 52  ? -18.27798 9.01437   36.73511  1.000 34.90129  ? 32  ALA A O   1 
ATOM   1486 C  CB  . ALA B 1 52  ? -19.51300 11.48882  34.87315  1.000 23.32122  ? 32  ALA A CB  1 
ATOM   1487 N  N   . CYS B 1 53  ? -17.37419 9.17649   34.67257  1.000 32.80027  ? 33  CYS A N   1 
ATOM   1488 C  CA  . CYS B 1 53  ? -16.98210 7.77146   34.65265  1.000 31.55328  ? 33  CYS A CA  1 
ATOM   1489 C  C   . CYS B 1 53  ? -15.94240 7.47413   35.72628  1.000 28.93035  ? 33  CYS A C   1 
ATOM   1490 O  O   . CYS B 1 53  ? -15.99495 6.42150   36.37334  1.000 34.61299  ? 33  CYS A O   1 
ATOM   1491 C  CB  . CYS B 1 53  ? -16.45359 7.39318   33.26939  1.000 26.54294  ? 33  CYS A CB  1 
ATOM   1492 S  SG  . CYS B 1 53  ? -16.03617 5.64267   33.08342  1.000 31.43163  ? 33  CYS A SG  1 
ATOM   1493 N  N   . ASP B 1 54  ? -14.99020 8.38966   35.93108  1.000 27.95678  ? 34  ASP A N   1 
ATOM   1494 C  CA  . ASP B 1 54  ? -14.00849 8.21323   36.99668  1.000 28.12491  ? 34  ASP A CA  1 
ATOM   1495 C  C   . ASP B 1 54  ? -14.68956 8.12341   38.35515  1.000 32.92899  ? 34  ASP A C   1 
ATOM   1496 O  O   . ASP B 1 54  ? -14.35784 7.25567   39.16855  1.000 38.51443  ? 34  ASP A O   1 
ATOM   1497 C  CB  . ASP B 1 54  ? -12.99598 9.36147   36.99030  1.000 28.96511  ? 34  ASP A CB  1 
ATOM   1498 C  CG  . ASP B 1 54  ? -12.05057 9.30758   35.81129  1.000 35.14521  ? 34  ASP A CG  1 
ATOM   1499 O  OD1 . ASP B 1 54  ? -11.85722 8.21275   35.24977  1.000 42.53555  ? 34  ASP A OD1 1 
ATOM   1500 O  OD2 . ASP B 1 54  ? -11.50044 10.36807  35.44762  1.000 37.86906  ? 34  ASP A OD2 1 
ATOM   1501 N  N   . ALA B 1 55  ? -15.64569 9.01866   38.61950  1.000 32.06161  ? 35  ALA A N   1 
ATOM   1502 C  CA  . ALA B 1 55  ? -16.33735 9.00573   39.90490  1.000 34.28475  ? 35  ALA A CA  1 
ATOM   1503 C  C   . ALA B 1 55  ? -17.09781 7.70040   40.10281  1.000 36.70982  ? 35  ALA A C   1 
ATOM   1504 O  O   . ALA B 1 55  ? -17.03712 7.08874   41.17824  1.000 38.66379  ? 35  ALA A O   1 
ATOM   1505 C  CB  . ALA B 1 55  ? -17.28000 10.20779  40.00973  1.000 26.79478  ? 35  ALA A CB  1 
ATOM   1506 N  N   . HIS B 1 56  ? -17.81785 7.25537   39.06907  1.000 40.27934  ? 36  HIS A N   1 
ATOM   1507 C  CA  . HIS B 1 56  ? -18.58107 6.01604   39.18298  1.000 38.30299  ? 36  HIS A CA  1 
ATOM   1508 C  C   . HIS B 1 56  ? -17.66485 4.82661   39.43993  1.000 36.73377  ? 36  HIS A C   1 
ATOM   1509 O  O   . HIS B 1 56  ? -17.90997 4.02171   40.34713  1.000 37.00149  ? 36  HIS A O   1 
ATOM   1510 C  CB  . HIS B 1 56  ? -19.40867 5.78377   37.91929  1.000 37.58474  ? 36  HIS A CB  1 
ATOM   1511 C  CG  . HIS B 1 56  ? -20.30437 4.58482   38.00004  1.000 45.38365  ? 36  HIS A CG  1 
ATOM   1512 N  ND1 . HIS B 1 56  ? -19.82610 3.29196   37.95712  1.000 49.65082  ? 36  HIS A ND1 1 
ATOM   1513 C  CD2 . HIS B 1 56  ? -21.64876 4.48263   38.12839  1.000 41.91210  ? 36  HIS A CD2 1 
ATOM   1514 C  CE1 . HIS B 1 56  ? -20.83623 2.44595   38.05126  1.000 46.32334  ? 36  HIS A CE1 1 
ATOM   1515 N  NE2 . HIS B 1 56  ? -21.95344 3.14282   38.15620  1.000 43.53681  ? 36  HIS A NE2 1 
ATOM   1516 N  N   . GLN B 1 57  ? -16.60440 4.69448   38.64100  1.000 39.49824  ? 37  GLN A N   1 
ATOM   1517 C  CA  . GLN B 1 57  ? -15.72169 3.54365   38.77367  1.000 37.54096  ? 37  GLN A CA  1 
ATOM   1518 C  C   . GLN B 1 57  ? -14.95001 3.56699   40.08849  1.000 40.73296  ? 37  GLN A C   1 
ATOM   1519 O  O   . GLN B 1 57  ? -14.70447 2.50631   40.67536  1.000 43.68221  ? 37  GLN A O   1 
ATOM   1520 C  CB  . GLN B 1 57  ? -14.77087 3.48494   37.57995  1.000 35.58289  ? 37  GLN A CB  1 
ATOM   1521 C  CG  . GLN B 1 57  ? -15.46276 3.17071   36.25813  1.000 30.20903  ? 37  GLN A CG  1 
ATOM   1522 C  CD  . GLN B 1 57  ? -14.48645 3.07371   35.10476  1.000 56.18901  ? 37  GLN A CD  1 
ATOM   1523 O  OE1 . GLN B 1 57  ? -13.53872 3.85441   35.01469  1.000 51.36916  ? 37  GLN A OE1 1 
ATOM   1524 N  NE2 . GLN B 1 57  ? -14.70538 2.10552   34.21994  1.000 63.68733  ? 37  GLN A NE2 1 
ATOM   1525 N  N   . ALA B 1 58  ? -14.57912 4.75270   40.58072  1.000 33.42098  ? 38  ALA A N   1 
ATOM   1526 C  CA  . ALA B 1 58  ? -13.91650 4.83262   41.87705  1.000 33.64277  ? 38  ALA A CA  1 
ATOM   1527 C  C   . ALA B 1 58  ? -14.86686 4.44170   43.00224  1.000 43.70367  ? 38  ALA A C   1 
ATOM   1528 O  O   . ALA B 1 58  ? -14.48479 3.69765   43.91281  1.000 45.96333  ? 38  ALA A O   1 
ATOM   1529 C  CB  . ALA B 1 58  ? -13.36283 6.24093   42.09550  1.000 31.06283  ? 38  ALA A CB  1 
ATOM   1530 N  N   . ALA B 1 59  ? -16.11650 4.91528   42.94825  1.000 39.52696  ? 39  ALA A N   1 
ATOM   1531 C  CA  . ALA B 1 59  ? -17.09701 4.51448   43.95307  1.000 40.95911  ? 39  ALA A CA  1 
ATOM   1532 C  C   . ALA B 1 59  ? -17.34249 3.00967   43.91843  1.000 44.72954  ? 39  ALA A C   1 
ATOM   1533 O  O   . ALA B 1 59  ? -17.51163 2.37727   44.96926  1.000 43.48702  ? 39  ALA A O   1 
ATOM   1534 C  CB  . ALA B 1 59  ? -18.40566 5.28173   43.74819  1.000 33.78870  ? 39  ALA A CB  1 
ATOM   1535 N  N   . ALA B 1 60  ? -17.35459 2.41688   42.71824  1.000 40.17534  ? 40  ALA A N   1 
ATOM   1536 C  CA  . ALA B 1 60  ? -17.61815 0.98581   42.58621  1.000 33.74498  ? 40  ALA A CA  1 
ATOM   1537 C  C   . ALA B 1 60  ? -16.44326 0.12296   43.03084  1.000 39.64104  ? 40  ALA A C   1 
ATOM   1538 O  O   . ALA B 1 60  ? -16.65693 -0.95388  43.59747  1.000 45.56079  ? 40  ALA A O   1 
ATOM   1539 C  CB  . ALA B 1 60  ? -17.97451 0.64724   41.13838  1.000 31.88575  ? 40  ALA A CB  1 
ATOM   1540 N  N   . SER B 1 61  ? -15.21011 0.56645   42.78876  1.000 42.23640  ? 41  SER A N   1 
ATOM   1541 C  CA  . SER B 1 61  ? -14.02533 -0.22060  43.09965  1.000 47.91392  ? 41  SER A CA  1 
ATOM   1542 C  C   . SER B 1 61  ? -13.33397 0.22539   44.38089  1.000 48.71942  ? 41  SER A C   1 
ATOM   1543 O  O   . SER B 1 61  ? -12.26055 -0.29231  44.70214  1.000 51.92049  ? 41  SER A O   1 
ATOM   1544 C  CB  . SER B 1 61  ? -13.03777 -0.17408  41.92912  1.000 46.84189  ? 41  SER A CB  1 
ATOM   1545 O  OG  . SER B 1 61  ? -12.63142 1.15337   41.63671  1.000 53.19127  ? 41  SER A OG  1 
ATOM   1546 N  N   . GLY B 1 62  ? -13.91894 1.16509   45.11919  1.000 50.19919  ? 42  GLY A N   1 
ATOM   1547 C  CA  . GLY B 1 62  ? -13.29669 1.62817   46.34481  1.000 53.45001  ? 42  GLY A CA  1 
ATOM   1548 C  C   . GLY B 1 62  ? -11.97513 2.33589   46.15589  1.000 56.17454  ? 42  GLY A C   1 
ATOM   1549 O  O   . GLY B 1 62  ? -11.17649 2.39881   47.09409  1.000 65.55339  ? 42  GLY A O   1 
ATOM   1550 N  N   . THR B 1 63  ? -11.71578 2.86806   44.96504  1.000 53.74958  ? 43  THR A N   1 
ATOM   1551 C  CA  . THR B 1 63  ? -10.49599 3.60519   44.68461  1.000 44.97669  ? 43  THR A CA  1 
ATOM   1552 C  C   . THR B 1 63  ? -10.78465 5.10421   44.69852  1.000 44.27135  ? 43  THR A C   1 
ATOM   1553 O  O   . THR B 1 63  ? -11.92099 5.54648   44.88326  1.000 48.22860  ? 43  THR A O   1 
ATOM   1554 C  CB  . THR B 1 63  ? -9.90148  3.18044   43.33801  1.000 57.29485  ? 43  THR A CB  1 
ATOM   1555 O  OG1 . THR B 1 63  ? -10.71643 3.68365   42.27010  1.000 50.69872  ? 43  THR A OG1 1 
ATOM   1556 C  CG2 . THR B 1 63  ? -9.82400  1.66429   43.23736  1.000 45.82660  ? 43  THR A CG2 1 
ATOM   1557 N  N   . SER B 1 64  ? -9.73531  5.89577   44.50394  1.000 43.78643  ? 44  SER A N   1 
ATOM   1558 C  CA  . SER B 1 64  ? -9.86500  7.33652   44.34789  1.000 47.32810  ? 44  SER A CA  1 
ATOM   1559 C  C   . SER B 1 64  ? -9.73267  7.69697   42.87434  1.000 51.37738  ? 44  SER A C   1 
ATOM   1560 O  O   . SER B 1 64  ? -8.88707  7.14525   42.16316  1.000 47.33628  ? 44  SER A O   1 
ATOM   1561 C  CB  . SER B 1 64  ? -8.81089  8.07984   45.17040  1.000 52.45136  ? 44  SER A CB  1 
ATOM   1562 O  OG  . SER B 1 64  ? -7.50439  7.79362   44.70418  1.000 59.69388  ? 44  SER A OG  1 
ATOM   1563 N  N   . ALA B 1 65  ? -10.57975 8.61357   42.41930  1.000 46.98282  ? 45  ALA A N   1 
ATOM   1564 C  CA  . ALA B 1 65  ? -10.55419 9.00989   41.02125  1.000 45.81380  ? 45  ALA A CA  1 
ATOM   1565 C  C   . ALA B 1 65  ? -9.23579  9.71041   40.69877  1.000 41.95974  ? 45  ALA A C   1 
ATOM   1566 O  O   . ALA B 1 65  ? -8.73688  10.49752  41.50746  1.000 47.56087  ? 45  ALA A O   1 
ATOM   1567 C  CB  . ALA B 1 65  ? -11.73140 9.93406   40.70524  1.000 40.11679  ? 45  ALA A CB  1 
ATOM   1568 N  N   . PRO B 1 66  ? -8.63984  9.43616   39.54112  1.000 49.18432  ? 46  PRO A N   1 
ATOM   1569 C  CA  . PRO B 1 66  ? -7.39906  10.12724  39.17835  1.000 48.51317  ? 46  PRO A CA  1 
ATOM   1570 C  C   . PRO B 1 66  ? -7.64809  11.60157  38.90441  1.000 46.11397  ? 46  PRO A C   1 
ATOM   1571 O  O   . PRO B 1 66  ? -8.75088  12.01286  38.53648  1.000 44.07762  ? 46  PRO A O   1 
ATOM   1572 C  CB  . PRO B 1 66  ? -6.94009  9.39332   37.91194  1.000 45.61854  ? 46  PRO A CB  1 
ATOM   1573 C  CG  . PRO B 1 66  ? -8.19092  8.82203   37.33459  1.000 35.98411  ? 46  PRO A CG  1 
ATOM   1574 C  CD  . PRO B 1 66  ? -9.04703  8.45590   38.51846  1.000 43.04074  ? 46  PRO A CD  1 
ATOM   1575 N  N   . ALA B 1 67  ? -6.60473  12.40344  39.10403  1.000 49.45796  ? 47  ALA A N   1 
ATOM   1576 C  CA  . ALA B 1 67  ? -6.67331  13.83318  38.82437  1.000 45.54683  ? 47  ALA A CA  1 
ATOM   1577 C  C   . ALA B 1 67  ? -6.49381  14.03982  37.32587  1.000 40.06326  ? 47  ALA A C   1 
ATOM   1578 O  O   . ALA B 1 67  ? -5.39531  13.85216  36.79219  1.000 40.00726  ? 47  ALA A O   1 
ATOM   1579 C  CB  . ALA B 1 67  ? -5.61533  14.59101  39.62206  1.000 31.07056  ? 47  ALA A CB  1 
ATOM   1580 N  N   . ARG B 1 68  ? -7.56806  14.43260  36.64771  1.000 36.26545  ? 48  ARG A N   1 
ATOM   1581 C  CA  . ARG B 1 68  ? -7.54342  14.63281  35.20665  1.000 35.14280  ? 48  ARG A CA  1 
ATOM   1582 C  C   . ARG B 1 68  ? -7.14171  16.06300  34.87303  1.000 36.86579  ? 48  ARG A C   1 
ATOM   1583 O  O   . ARG B 1 68  ? -7.58362  17.01504  35.52354  1.000 29.05959  ? 48  ARG A O   1 
ATOM   1584 C  CB  . ARG B 1 68  ? -8.91182  14.31970  34.60291  1.000 39.37967  ? 48  ARG A CB  1 
ATOM   1585 C  CG  . ARG B 1 68  ? -9.39074  12.89812  34.85382  1.000 38.95894  ? 48  ARG A CG  1 
ATOM   1586 C  CD  . ARG B 1 68  ? -8.49464  11.87716  34.16719  1.000 27.87787  ? 48  ARG A CD  1 
ATOM   1587 N  NE  . ARG B 1 68  ? -9.11015  10.55572  34.15511  1.000 36.56006  ? 48  ARG A NE  1 
ATOM   1588 C  CZ  . ARG B 1 68  ? -8.60298  9.49416   33.54383  1.000 29.62461  ? 48  ARG A CZ  1 
ATOM   1589 N  NH1 . ARG B 1 68  ? -7.46218  9.55905   32.87671  1.000 34.23692  ? 48  ARG A NH1 1 
ATOM   1590 N  NH2 . ARG B 1 68  ? -9.25636  8.33771   33.60537  1.000 30.20226  ? 48  ARG A NH2 1 
ATOM   1591 N  N   . ARG B 1 69  ? -6.30015  16.20589  33.85244  1.000 37.63359  ? 49  ARG A N   1 
ATOM   1592 C  CA  . ARG B 1 69  ? -5.79063  17.50770  33.44226  1.000 33.47480  ? 49  ARG A CA  1 
ATOM   1593 C  C   . ARG B 1 69  ? -6.66709  18.10213  32.34754  1.000 38.37440  ? 49  ARG A C   1 
ATOM   1594 O  O   . ARG B 1 69  ? -6.90928  17.46072  31.32040  1.000 35.33755  ? 49  ARG A O   1 
ATOM   1595 C  CB  . ARG B 1 69  ? -4.34675  17.39640  32.95238  1.000 44.27140  ? 49  ARG A CB  1 
ATOM   1596 C  CG  . ARG B 1 69  ? -3.32218  17.24599  34.06288  1.000 42.80222  ? 49  ARG A CG  1 
ATOM   1597 C  CD  . ARG B 1 69  ? -2.00351  17.89564  33.67515  1.000 49.87186  ? 49  ARG A CD  1 
ATOM   1598 N  NE  . ARG B 1 69  ? -1.14007  18.09984  34.83118  1.000 63.98666  ? 49  ARG A NE  1 
ATOM   1599 C  CZ  . ARG B 1 69  ? -0.13719  17.30154  35.16909  1.000 69.25759  ? 49  ARG A CZ  1 
ATOM   1600 N  NH1 . ARG B 1 69  ? 0.17699   16.24097  34.44330  1.000 66.44266  ? 49  ARG A NH1 1 
ATOM   1601 N  NH2 . ARG B 1 69  ? 0.56938   17.57534  36.26206  1.000 64.00296  ? 49  ARG A NH2 1 
ATOM   1602 N  N   . MET B 1 70  ? -7.14438  19.32858  32.57911  1.000 48.64635  ? 50  MET A N   1 
ATOM   1603 C  CA  . MET B 1 70  ? -7.89831  20.04197  31.55326  1.000 42.30293  ? 50  MET A CA  1 
ATOM   1604 C  C   . MET B 1 70  ? -7.05348  20.27297  30.30647  1.000 43.90021  ? 50  MET A C   1 
ATOM   1605 O  O   . MET B 1 70  ? -7.55288  20.16393  29.17950  1.000 42.94315  ? 50  MET A O   1 
ATOM   1606 C  CB  . MET B 1 70  ? -8.40584  21.37450  32.10753  1.000 52.91887  ? 50  MET A CB  1 
ATOM   1607 C  CG  . MET B 1 70  ? -9.84436  21.34866  32.58472  1.000 43.61076  ? 50  MET A CG  1 
ATOM   1608 S  SD  . MET B 1 70  ? -10.99878 21.08055  31.22706  1.000 71.95993  ? 50  MET A SD  1 
ATOM   1609 C  CE  . MET B 1 70  ? -10.48974 22.37290  30.09652  1.000 56.85367  ? 50  MET A CE  1 
ATOM   1610 N  N   . GLU B 1 71  ? -5.77129  20.60282  30.48742  1.000 44.17036  ? 51  GLU A N   1 
ATOM   1611 C  CA  . GLU B 1 71  ? -4.90362  20.83157  29.33693  1.000 44.01747  ? 51  GLU A CA  1 
ATOM   1612 C  C   . GLU B 1 71  ? -4.72281  19.56409  28.51149  1.000 36.64157  ? 51  GLU A C   1 
ATOM   1613 O  O   . GLU B 1 71  ? -4.63750  19.63413  27.28070  1.000 43.96467  ? 51  GLU A O   1 
ATOM   1614 C  CB  . GLU B 1 71  ? -3.54807  21.37946  29.79256  1.000 43.69068  ? 51  GLU A CB  1 
ATOM   1615 C  CG  . GLU B 1 71  ? -2.83124  20.54560  30.84746  1.000 45.11719  ? 51  GLU A CG  1 
ATOM   1616 C  CD  . GLU B 1 71  ? -3.09208  21.03120  32.26238  1.000 51.24754  ? 51  GLU A CD  1 
ATOM   1617 O  OE1 . GLU B 1 71  ? -4.26858  21.27783  32.60489  1.000 58.97244  ? 51  GLU A OE1 1 
ATOM   1618 O  OE2 . GLU B 1 71  ? -2.11650  21.17303  33.03165  1.000 44.08088  ? 51  GLU A OE2 1 
ATOM   1619 N  N   . THR B 1 72  ? -4.68018  18.39908  29.16239  1.000 42.58022  ? 52  THR A N   1 
ATOM   1620 C  CA  . THR B 1 72  ? -4.60988  17.14282  28.42188  1.000 33.88874  ? 52  THR A CA  1 
ATOM   1621 C  C   . THR B 1 72  ? -5.87080  16.92492  27.59278  1.000 34.22387  ? 52  THR A C   1 
ATOM   1622 O  O   . THR B 1 72  ? -5.79404  16.52590  26.42375  1.000 33.17194  ? 52  THR A O   1 
ATOM   1623 C  CB  . THR B 1 72  ? -4.38390  15.97732  29.38801  1.000 39.23421  ? 52  THR A CB  1 
ATOM   1624 O  OG1 . THR B 1 72  ? -3.09569  16.11001  30.00305  1.000 31.17498  ? 52  THR A OG1 1 
ATOM   1625 C  CG2 . THR B 1 72  ? -4.45424  14.63466  28.65660  1.000 34.02226  ? 52  THR A CG2 1 
ATOM   1626 N  N   . THR B 1 73  ? -7.04143  17.19337  28.17780  1.000 28.03698  ? 53  THR A N   1 
ATOM   1627 C  CA  . THR B 1 73  ? -8.28590  17.07987  27.42395  1.000 35.50057  ? 53  THR A CA  1 
ATOM   1628 C  C   . THR B 1 73  ? -8.29147  18.02456  26.22810  1.000 40.32841  ? 53  THR A C   1 
ATOM   1629 O  O   . THR B 1 73  ? -8.68115  17.63336  25.12176  1.000 34.71942  ? 53  THR A O   1 
ATOM   1630 C  CB  . THR B 1 73  ? -9.48256  17.36218  28.33258  1.000 34.31943  ? 53  THR A CB  1 
ATOM   1631 O  OG1 . THR B 1 73  ? -9.50073  16.42213  29.41381  1.000 34.90936  ? 53  THR A OG1 1 
ATOM   1632 C  CG2 . THR B 1 73  ? -10.77703 17.24365  27.55500  1.000 35.70147  ? 53  THR A CG2 1 
ATOM   1633 N  N   . GLU B 1 74  ? -7.85781  19.27233  26.43129  1.000 33.41562  ? 54  GLU A N   1 
ATOM   1634 C  CA  . GLU B 1 74  ? -7.79332  20.22983  25.32955  1.000 32.27168  ? 54  GLU A CA  1 
ATOM   1635 C  C   . GLU B 1 74  ? -6.86591  19.73716  24.22574  1.000 36.83789  ? 54  GLU A C   1 
ATOM   1636 O  O   . GLU B 1 74  ? -7.21098  19.78847  23.03883  1.000 38.14715  ? 54  GLU A O   1 
ATOM   1637 C  CB  . GLU B 1 74  ? -7.33020  21.59510  25.84048  1.000 34.13142  ? 54  GLU A CB  1 
ATOM   1638 C  CG  . GLU B 1 74  ? -8.32516  22.30384  26.74457  1.000 40.02619  ? 54  GLU A CG  1 
ATOM   1639 C  CD  . GLU B 1 74  ? -7.80390  23.63876  27.24565  1.000 42.59652  ? 54  GLU A CD  1 
ATOM   1640 O  OE1 . GLU B 1 74  ? -6.59460  23.91146  27.08251  1.000 48.88886  ? 54  GLU A OE1 1 
ATOM   1641 O  OE2 . GLU B 1 74  ? -8.60427  24.41742  27.80312  1.000 43.91400  ? 54  GLU A OE2 1 
ATOM   1642 N  N   . HIS B 1 75  ? -5.67814  19.25464  24.60182  1.000 28.93316  ? 55  HIS A N   1 
ATOM   1643 C  CA  . HIS B 1 75  ? -4.71906  18.78731  23.60725  1.000 29.56852  ? 55  HIS A CA  1 
ATOM   1644 C  C   . HIS B 1 75  ? -5.25524  17.58514  22.83832  1.000 35.92659  ? 55  HIS A C   1 
ATOM   1645 O  O   . HIS B 1 75  ? -5.05301  17.47742  21.62339  1.000 34.73537  ? 55  HIS A O   1 
ATOM   1646 C  CB  . HIS B 1 75  ? -3.39059  18.44398  24.28000  1.000 30.61541  ? 55  HIS A CB  1 
ATOM   1647 C  CG  . HIS B 1 75  ? -2.39735  17.80746  23.35866  1.000 42.07599  ? 55  HIS A CG  1 
ATOM   1648 N  ND1 . HIS B 1 75  ? -1.88809  18.45542  22.25343  1.000 51.43023  ? 55  HIS A ND1 1 
ATOM   1649 C  CD2 . HIS B 1 75  ? -1.82373  16.58050  23.37349  1.000 38.39233  ? 55  HIS A CD2 1 
ATOM   1650 C  CE1 . HIS B 1 75  ? -1.04128  17.65658  21.62888  1.000 49.24515  ? 55  HIS A CE1 1 
ATOM   1651 N  NE2 . HIS B 1 75  ? -0.98422  16.51285  22.28777  1.000 40.45726  ? 55  HIS A NE2 1 
ATOM   1652 N  N   . ARG B 1 76  ? -5.94540  16.67093  23.52523  1.000 31.30339  ? 56  ARG A N   1 
ATOM   1653 C  CA  . ARG B 1 76  ? -6.45670  15.48291  22.84736  1.000 30.89239  ? 56  ARG A CA  1 
ATOM   1654 C  C   . ARG B 1 76  ? -7.62657  15.82301  21.93187  1.000 36.55924  ? 56  ARG A C   1 
ATOM   1655 O  O   . ARG B 1 76  ? -7.73902  15.27068  20.83048  1.000 33.94450  ? 56  ARG A O   1 
ATOM   1656 C  CB  . ARG B 1 76  ? -6.87001  14.42204  23.86756  1.000 29.59019  ? 56  ARG A CB  1 
ATOM   1657 C  CG  . ARG B 1 76  ? -5.71849  13.83563  24.66230  1.000 26.15388  ? 56  ARG A CG  1 
ATOM   1658 C  CD  . ARG B 1 76  ? -4.57726  13.42441  23.75619  1.000 23.47659  ? 56  ARG A CD  1 
ATOM   1659 N  NE  . ARG B 1 76  ? -3.44276  12.91138  24.51410  1.000 30.85165  ? 56  ARG A NE  1 
ATOM   1660 C  CZ  . ARG B 1 76  ? -2.23569  12.70511  24.00570  1.000 39.71798  ? 56  ARG A CZ  1 
ATOM   1661 N  NH1 . ARG B 1 76  ? -1.96245  12.97742  22.73980  1.000 42.12103  ? 56  ARG A NH1 1 
ATOM   1662 N  NH2 . ARG B 1 76  ? -1.27826  12.21431  24.78697  1.000 43.00954  ? 56  ARG A NH2 1 
ATOM   1663 N  N   . VAL B 1 77  ? -8.50823  16.72639  22.36616  1.000 36.59389  ? 57  VAL A N   1 
ATOM   1664 C  CA  . VAL B 1 77  ? -9.66753  17.08104  21.55329  1.000 30.53309  ? 57  VAL A CA  1 
ATOM   1665 C  C   . VAL B 1 77  ? -9.23694  17.88046  20.32972  1.000 41.25667  ? 57  VAL A C   1 
ATOM   1666 O  O   . VAL B 1 77  ? -9.67398  17.60676  19.20561  1.000 39.68193  ? 57  VAL A O   1 
ATOM   1667 C  CB  . VAL B 1 77  ? -10.70027 17.84620  22.39946  1.000 34.96679  ? 57  VAL A CB  1 
ATOM   1668 C  CG1 . VAL B 1 77  ? -11.77857 18.44918  21.51454  1.000 35.43142  ? 57  VAL A CG1 1 
ATOM   1669 C  CG2 . VAL B 1 77  ? -11.32140 16.91813  23.43073  1.000 32.32378  ? 57  VAL A CG2 1 
ATOM   1670 N  N   . ARG B 1 78  ? -8.36271  18.87246  20.52549  1.000 47.45827  ? 58  ARG A N   1 
ATOM   1671 C  CA  . ARG B 1 78  ? -7.93277  19.70389  19.40562  1.000 41.93627  ? 58  ARG A CA  1 
ATOM   1672 C  C   . ARG B 1 78  ? -7.14974  18.90241  18.37530  1.000 47.01275  ? 58  ARG A C   1 
ATOM   1673 O  O   . ARG B 1 78  ? -7.18229  19.22887  17.18378  1.000 50.31043  ? 58  ARG A O   1 
ATOM   1674 C  CB  . ARG B 1 78  ? -7.09726  20.88160  19.91134  1.000 44.20802  ? 58  ARG A CB  1 
ATOM   1675 C  CG  . ARG B 1 78  ? -7.86998  21.89360  20.75398  1.000 52.07007  ? 58  ARG A CG  1 
ATOM   1676 C  CD  . ARG B 1 78  ? -8.68122  22.87172  19.90663  1.000 59.20942  ? 58  ARG A CD  1 
ATOM   1677 N  NE  . ARG B 1 78  ? -9.85035  22.26375  19.28115  1.000 64.73473  ? 58  ARG A NE  1 
ATOM   1678 C  CZ  . ARG B 1 78  ? -11.02669 22.11598  19.87575  1.000 59.59714  ? 58  ARG A CZ  1 
ATOM   1679 N  NH1 . ARG B 1 78  ? -11.22341 22.50389  21.12554  1.000 56.05489  ? 58  ARG A NH1 1 
ATOM   1680 N  NH2 . ARG B 1 78  ? -12.03067 21.56337  19.20033  1.000 56.52727  ? 58  ARG A NH2 1 
ATOM   1681 N  N   . SER B 1 79  ? -6.45062  17.85321  18.80634  1.000 44.82471  ? 59  SER A N   1 
ATOM   1682 C  CA  . SER B 1 79  ? -5.69396  17.00519  17.89401  1.000 37.85463  ? 59  SER A CA  1 
ATOM   1683 C  C   . SER B 1 79  ? -6.57031  16.01264  17.14117  1.000 44.57355  ? 59  SER A C   1 
ATOM   1684 O  O   . SER B 1 79  ? -6.06070  15.30344  16.26678  1.000 46.79530  ? 59  SER A O   1 
ATOM   1685 C  CB  . SER B 1 79  ? -4.60349  16.24832  18.66174  1.000 35.86990  ? 59  SER A CB  1 
ATOM   1686 O  OG  . SER B 1 79  ? -3.71641  17.14829  19.30482  1.000 44.76996  ? 59  SER A OG  1 
ATOM   1687 N  N   . GLY B 1 80  ? -7.86324  15.94659  17.45022  1.000 41.05019  ? 60  GLY A N   1 
ATOM   1688 C  CA  . GLY B 1 80  ? -8.73563  14.98774  16.80083  1.000 39.87624  ? 60  GLY A CA  1 
ATOM   1689 C  C   . GLY B 1 80  ? -8.50777  13.55730  17.23009  1.000 40.47072  ? 60  GLY A C   1 
ATOM   1690 O  O   . GLY B 1 80  ? -8.79361  12.63382  16.46297  1.000 40.88974  ? 60  GLY A O   1 
ATOM   1691 N  N   . SER B 1 81  ? -8.00384  13.34863  18.44441  1.000 36.15126  ? 61  SER A N   1 
ATOM   1692 C  CA  . SER B 1 81  ? -7.68808  12.02200  18.95226  1.000 33.38949  ? 61  SER A CA  1 
ATOM   1693 C  C   . SER B 1 81  ? -8.79145  11.43254  19.82191  1.000 31.24596  ? 61  SER A C   1 
ATOM   1694 O  O   . SER B 1 81  ? -8.67164  10.28006  20.24829  1.000 34.18214  ? 61  SER A O   1 
ATOM   1695 C  CB  . SER B 1 81  ? -6.37826  12.06355  19.74813  1.000 35.53365  ? 61  SER A CB  1 
ATOM   1696 O  OG  . SER B 1 81  ? -5.31049  12.56183  18.95967  1.000 42.00125  ? 61  SER A OG  1 
ATOM   1697 N  N   . VAL B 1 82  ? -9.85428  12.18308  20.09769  1.000 34.79302  ? 62  VAL A N   1 
ATOM   1698 C  CA  . VAL B 1 82  ? -10.92367 11.73616  20.98414  1.000 33.57082  ? 62  VAL A CA  1 
ATOM   1699 C  C   . VAL B 1 82  ? -12.11293 11.31076  20.13589  1.000 33.44897  ? 62  VAL A C   1 
ATOM   1700 O  O   . VAL B 1 82  ? -12.68931 12.12405  19.40345  1.000 38.19128  ? 62  VAL A O   1 
ATOM   1701 C  CB  . VAL B 1 82  ? -11.31958 12.83304  21.98464  1.000 26.43770  ? 62  VAL A CB  1 
ATOM   1702 C  CG1 . VAL B 1 82  ? -12.39252 12.32617  22.93786  1.000 25.14044  ? 62  VAL A CG1 1 
ATOM   1703 C  CG2 . VAL B 1 82  ? -10.10014 13.29822  22.75023  1.000 30.55822  ? 62  VAL A CG2 1 
ATOM   1704 N  N   . HIS B 1 83  ? -12.47921 10.03687  20.23407  1.000 35.74299  ? 63  HIS A N   1 
ATOM   1705 C  CA  . HIS B 1 83  ? -13.63520 9.48908   19.54036  1.000 32.67790  ? 63  HIS A CA  1 
ATOM   1706 C  C   . HIS B 1 83  ? -14.73622 9.24013   20.55874  1.000 30.70983  ? 63  HIS A C   1 
ATOM   1707 O  O   . HIS B 1 83  ? -14.51714 8.54321   21.55661  1.000 34.39792  ? 63  HIS A O   1 
ATOM   1708 C  CB  . HIS B 1 83  ? -13.27331 8.19954   18.80146  1.000 31.52469  ? 63  HIS A CB  1 
ATOM   1709 C  CG  . HIS B 1 83  ? -12.15801 8.36529   17.81728  1.000 38.19250  ? 63  HIS A CG  1 
ATOM   1710 N  ND1 . HIS B 1 83  ? -12.35324 8.30497   16.45349  1.000 36.15456  ? 63  HIS A ND1 1 
ATOM   1711 C  CD2 . HIS B 1 83  ? -10.83746 8.60435   17.99926  1.000 27.50049  ? 63  HIS A CD2 1 
ATOM   1712 C  CE1 . HIS B 1 83  ? -11.19955 8.49247   15.83820  1.000 35.67389  ? 63  HIS A CE1 1 
ATOM   1713 N  NE2 . HIS B 1 83  ? -10.26432 8.67759   16.75322  1.000 35.70189  ? 63  HIS A NE2 1 
ATOM   1714 N  N   . LEU B 1 84  ? -15.91056 9.81411   20.30344  1.000 31.21625  ? 64  LEU A N   1 
ATOM   1715 C  CA  . LEU B 1 84  ? -17.02650 9.80683   21.23661  1.000 31.53821  ? 64  LEU A CA  1 
ATOM   1716 C  C   . LEU B 1 84  ? -18.23821 9.13171   20.60414  1.000 39.27603  ? 64  LEU A C   1 
ATOM   1717 O  O   . LEU B 1 84  ? -18.53741 9.34018   19.42248  1.000 39.14066  ? 64  LEU A O   1 
ATOM   1718 C  CB  . LEU B 1 84  ? -17.37769 11.23829  21.67162  1.000 32.99783  ? 64  LEU A CB  1 
ATOM   1719 C  CG  . LEU B 1 84  ? -18.36172 11.41982  22.82839  1.000 35.59109  ? 64  LEU A CG  1 
ATOM   1720 C  CD1 . LEU B 1 84  ? -17.91561 12.56465  23.71650  1.000 43.03943  ? 64  LEU A CD1 1 
ATOM   1721 C  CD2 . LEU B 1 84  ? -19.76112 11.67848  22.30480  1.000 44.30664  ? 64  LEU A CD2 1 
ATOM   1722 N  N   . LEU B 1 85  ? -18.93257 8.32696   21.40640  1.000 40.21000  ? 65  LEU A N   1 
ATOM   1723 C  CA  . LEU B 1 85  ? -20.12139 7.58475   21.00728  1.000 37.20033  ? 65  LEU A CA  1 
ATOM   1724 C  C   . LEU B 1 85  ? -21.33188 8.17682   21.71471  1.000 46.10215  ? 65  LEU A C   1 
ATOM   1725 O  O   . LEU B 1 85  ? -21.39089 8.17362   22.95255  1.000 44.36854  ? 65  LEU A O   1 
ATOM   1726 C  CB  . LEU B 1 85  ? -19.98283 6.10257   21.35713  1.000 33.48921  ? 65  LEU A CB  1 
ATOM   1727 C  CG  . LEU B 1 85  ? -21.24217 5.23492   21.25102  1.000 42.13817  ? 65  LEU A CG  1 
ATOM   1728 C  CD1 . LEU B 1 85  ? -21.71720 5.14653   19.81021  1.000 42.72025  ? 65  LEU A CD1 1 
ATOM   1729 C  CD2 . LEU B 1 85  ? -21.00401 3.84107   21.82448  1.000 32.61161  ? 65  LEU A CD2 1 
ATOM   1730 N  N   . ARG B 1 86  ? -22.28717 8.66869   20.92612  1.000 47.16167  ? 66  ARG A N   1 
ATOM   1731 C  CA  . ARG B 1 86  ? -23.54882 9.21599   21.39782  1.000 45.87318  ? 66  ARG A CA  1 
ATOM   1732 C  C   . ARG B 1 86  ? -24.67655 8.21049   21.21232  1.000 50.67809  ? 66  ARG A C   1 
ATOM   1733 O  O   . ARG B 1 86  ? -24.70063 7.44179   20.24375  1.000 55.13239  ? 66  ARG A O   1 
ATOM   1734 C  CB  . ARG B 1 86  ? -23.91214 10.49944  20.64790  1.000 46.18489  ? 66  ARG A CB  1 
ATOM   1735 C  CG  . ARG B 1 86  ? -23.05908 11.69043  20.97873  1.000 50.97789  ? 66  ARG A CG  1 
ATOM   1736 C  CD  . ARG B 1 86  ? -23.52176 12.91550  20.20961  1.000 42.11477  ? 66  ARG A CD  1 
ATOM   1737 N  NE  . ARG B 1 86  ? -22.49805 13.95222  20.20583  1.000 50.01394  ? 66  ARG A NE  1 
ATOM   1738 C  CZ  . ARG B 1 86  ? -22.28071 14.78952  21.20989  1.000 44.72121  ? 66  ARG A CZ  1 
ATOM   1739 N  NH1 . ARG B 1 86  ? -23.01961 14.75923  22.30676  1.000 37.52227  ? 66  ARG A NH1 1 
ATOM   1740 N  NH2 . ARG B 1 86  ? -21.29192 15.67304  21.11497  1.000 39.97524  ? 66  ARG A NH2 1 
ATOM   1741 N  N   . HIS B 1 87  ? -25.62794 8.24977   22.14448  1.000 43.55070  ? 67  HIS A N   1 
ATOM   1742 C  CA  . HIS B 1 87  ? -26.86243 7.47711   22.06617  1.000 48.54252  ? 67  HIS A CA  1 
ATOM   1743 C  C   . HIS B 1 87  ? -28.02648 8.45101   22.18428  1.000 59.30740  ? 67  HIS A C   1 
ATOM   1744 O  O   . HIS B 1 87  ? -28.23080 9.05038   23.24532  1.000 63.27111  ? 67  HIS A O   1 
ATOM   1745 C  CB  . HIS B 1 87  ? -26.92203 6.41085   23.15917  1.000 45.19630  ? 67  HIS A CB  1 
ATOM   1746 C  CG  . HIS B 1 87  ? -28.17415 5.59142   23.13363  1.000 60.60816  ? 67  HIS A CG  1 
ATOM   1747 N  ND1 . HIS B 1 87  ? -28.45270 4.69135   22.12758  1.000 60.81308  ? 67  HIS A ND1 1 
ATOM   1748 C  CD2 . HIS B 1 87  ? -29.22542 5.54127   23.98592  1.000 56.91119  ? 67  HIS A CD2 1 
ATOM   1749 C  CE1 . HIS B 1 87  ? -29.61902 4.11792   22.36427  1.000 63.87689  ? 67  HIS A CE1 1 
ATOM   1750 N  NE2 . HIS B 1 87  ? -30.10851 4.61559   23.48596  1.000 64.29213  ? 67  HIS A NE2 1 
ATOM   1751 N  N   . ASP B 1 88  ? -28.78330 8.60470   21.09593  1.000 59.27169  ? 68  ASP A N   1 
ATOM   1752 C  CA  . ASP B 1 88  ? -29.89570 9.55517   21.02839  1.000 55.00194  ? 68  ASP A CA  1 
ATOM   1753 C  C   . ASP B 1 88  ? -29.43087 10.96916  21.37090  1.000 50.41946  ? 68  ASP A C   1 
ATOM   1754 O  O   . ASP B 1 88  ? -30.14498 11.74810  22.00854  1.000 62.51318  ? 68  ASP A O   1 
ATOM   1755 C  CB  . ASP B 1 88  ? -31.05283 9.12409   21.93257  1.000 57.39769  ? 68  ASP A CB  1 
ATOM   1756 C  CG  . ASP B 1 88  ? -31.68003 7.81255   21.49598  1.000 60.99054  ? 68  ASP A CG  1 
ATOM   1757 O  OD1 . ASP B 1 88  ? -31.50832 7.42551   20.31925  1.000 67.91069  ? 68  ASP A OD1 1 
ATOM   1758 O  OD2 . ASP B 1 88  ? -32.35215 7.16993   22.33037  1.000 61.55867  ? 68  ASP A OD2 1 
ATOM   1759 N  N   . GLY B 1 89  ? -28.21078 11.30126  20.94670  1.000 54.75227  ? 69  GLY A N   1 
ATOM   1760 C  CA  . GLY B 1 89  ? -27.63192 12.60466  21.17884  1.000 56.14399  ? 69  GLY A CA  1 
ATOM   1761 C  C   . GLY B 1 89  ? -26.79462 12.72306  22.43707  1.000 49.34494  ? 69  GLY A C   1 
ATOM   1762 O  O   . GLY B 1 89  ? -25.88032 13.55331  22.48231  1.000 49.51513  ? 69  GLY A O   1 
ATOM   1763 N  N   . ARG B 1 90  ? -27.08509 11.92387  23.45874  1.000 47.97688  ? 70  ARG A N   1 
ATOM   1764 C  CA  . ARG B 1 90  ? -26.33069 12.03098  24.70015  1.000 55.18308  ? 70  ARG A CA  1 
ATOM   1765 C  C   . ARG B 1 90  ? -25.02305 11.24706  24.60327  1.000 53.22195  ? 70  ARG A C   1 
ATOM   1766 O  O   . ARG B 1 90  ? -24.99286 10.15959  24.02331  1.000 52.30041  ? 70  ARG A O   1 
ATOM   1767 C  CB  . ARG B 1 90  ? -27.14703 11.51146  25.87850  1.000 56.40067  ? 70  ARG A CB  1 
ATOM   1768 C  CG  . ARG B 1 90  ? -28.28207 12.41786  26.30103  1.000 59.01310  ? 70  ARG A CG  1 
ATOM   1769 C  CD  . ARG B 1 90  ? -28.91911 11.90733  27.57944  1.000 61.68719  ? 70  ARG A CD  1 
ATOM   1770 N  NE  . ARG B 1 90  ? -29.21789 10.48290  27.49875  1.000 62.39608  ? 70  ARG A NE  1 
ATOM   1771 C  CZ  . ARG B 1 90  ? -30.29058 9.97535   26.90703  1.000 71.36208  ? 70  ARG A CZ  1 
ATOM   1772 N  NH1 . ARG B 1 90  ? -31.18996 10.75045  26.32308  1.000 65.21154  ? 70  ARG A NH1 1 
ATOM   1773 N  NH2 . ARG B 1 90  ? -30.46405 8.65659   26.89805  1.000 70.57371  ? 70  ARG A NH2 1 
ATOM   1774 N  N   . PRO B 1 91  ? -23.93545 11.77092  25.16626  1.000 51.99224  ? 71  PRO A N   1 
ATOM   1775 C  CA  . PRO B 1 91  ? -22.66864 11.02626  25.15723  1.000 44.64814  ? 71  PRO A CA  1 
ATOM   1776 C  C   . PRO B 1 91  ? -22.78637 9.74223   25.96526  1.000 41.51809  ? 71  PRO A C   1 
ATOM   1777 O  O   . PRO B 1 91  ? -23.16790 9.75883   27.13729  1.000 39.38709  ? 71  PRO A O   1 
ATOM   1778 C  CB  . PRO B 1 91  ? -21.67445 12.00549  25.79514  1.000 45.83542  ? 71  PRO A CB  1 
ATOM   1779 C  CG  . PRO B 1 91  ? -22.32781 13.34880  25.69980  1.000 40.69002  ? 71  PRO A CG  1 
ATOM   1780 C  CD  . PRO B 1 91  ? -23.79551 13.09780  25.78771  1.000 48.52110  ? 71  PRO A CD  1 
ATOM   1781 N  N   . ALA B 1 92  ? -22.45751 8.62256   25.32633  1.000 39.35914  ? 72  ALA A N   1 
ATOM   1782 C  CA  . ALA B 1 92  ? -22.50708 7.31116   25.96252  1.000 36.71311  ? 72  ALA A CA  1 
ATOM   1783 C  C   . ALA B 1 92  ? -21.13518 6.73797   26.27443  1.000 39.43374  ? 72  ALA A C   1 
ATOM   1784 O  O   . ALA B 1 92  ? -20.95936 6.10391   27.31830  1.000 30.32093  ? 72  ALA A O   1 
ATOM   1785 C  CB  . ALA B 1 92  ? -23.27406 6.32169   25.07838  1.000 34.20658  ? 72  ALA A CB  1 
ATOM   1786 N  N   . GLY B 1 93  ? -20.15865 6.93771   25.39386  1.000 32.53859  ? 73  GLY A N   1 
ATOM   1787 C  CA  . GLY B 1 93  ? -18.82152 6.43807   25.65953  1.000 26.10570  ? 73  GLY A CA  1 
ATOM   1788 C  C   . GLY B 1 93  ? -17.80639 7.23210   24.87099  1.000 32.04410  ? 73  GLY A C   1 
ATOM   1789 O  O   . GLY B 1 93  ? -18.15900 8.13136   24.10762  1.000 31.27095  ? 73  GLY A O   1 
ATOM   1790 N  N   . MET B 1 94  ? -16.53270 6.88421   25.05298  1.000 29.58167  ? 74  MET A N   1 
ATOM   1791 C  CA  . MET B 1 94  ? -15.47146 7.52028   24.27965  1.000 30.19116  ? 74  MET A CA  1 
ATOM   1792 C  C   . MET B 1 94  ? -14.14511 6.83578   24.57425  1.000 29.60506  ? 74  MET A C   1 
ATOM   1793 O  O   . MET B 1 94  ? -14.03115 6.00108   25.47701  1.000 24.49836  ? 74  MET A O   1 
ATOM   1794 C  CB  . MET B 1 94  ? -15.36033 9.01817   24.57889  1.000 26.16882  ? 74  MET A CB  1 
ATOM   1795 C  CG  . MET B 1 94  ? -14.88607 9.32922   25.97890  1.000 23.16239  ? 74  MET A CG  1 
ATOM   1796 S  SD  . MET B 1 94  ? -14.43815 11.06156  26.16305  1.000 26.30384  ? 74  MET A SD  1 
ATOM   1797 C  CE  . MET B 1 94  ? -14.12655 11.10538  27.92789  1.000 25.14038  ? 74  MET A CE  1 
ATOM   1798 N  N   . PHE B 1 95  ? -13.14293 7.21376   23.78489  1.000 29.38662  ? 75  PHE A N   1 
ATOM   1799 C  CA  . PHE B 1 95  ? -11.75767 6.81525   24.00116  1.000 27.63238  ? 75  PHE A CA  1 
ATOM   1800 C  C   . PHE B 1 95  ? -10.86222 7.83670   23.31267  1.000 31.07081  ? 75  PHE A C   1 
ATOM   1801 O  O   . PHE B 1 95  ? -11.32950 8.67077   22.53203  1.000 25.55225  ? 75  PHE A O   1 
ATOM   1802 C  CB  . PHE B 1 95  ? -11.48991 5.39136   23.49140  1.000 30.20945  ? 75  PHE A CB  1 
ATOM   1803 C  CG  . PHE B 1 95  ? -11.72984 5.20999   22.01627  1.000 35.13929  ? 75  PHE A CG  1 
ATOM   1804 C  CD1 . PHE B 1 95  ? -10.70614 5.40769   21.10117  1.000 28.14929  ? 75  PHE A CD1 1 
ATOM   1805 C  CD2 . PHE B 1 95  ? -12.97683 4.83061   21.54605  1.000 26.51495  ? 75  PHE A CD2 1 
ATOM   1806 C  CE1 . PHE B 1 95  ? -10.92598 5.23570   19.74494  1.000 36.53189  ? 75  PHE A CE1 1 
ATOM   1807 C  CE2 . PHE B 1 95  ? -13.20047 4.65758   20.18988  1.000 25.74363  ? 75  PHE A CE2 1 
ATOM   1808 C  CZ  . PHE B 1 95  ? -12.17589 4.86011   19.29064  1.000 25.89975  ? 75  PHE A CZ  1 
ATOM   1809 N  N   . THR B 1 96  ? -9.56496  7.76507   23.61523  1.000 29.29584  ? 76  THR A N   1 
ATOM   1810 C  CA  . THR B 1 96  ? -8.55114  8.60533   22.99736  1.000 23.94920  ? 76  THR A CA  1 
ATOM   1811 C  C   . THR B 1 96  ? -7.52935  7.69361   22.33772  1.000 25.15737  ? 76  THR A C   1 
ATOM   1812 O  O   . THR B 1 96  ? -7.00805  6.77437   22.97823  1.000 24.88747  ? 76  THR A O   1 
ATOM   1813 C  CB  . THR B 1 96  ? -7.87609  9.52009   24.03056  1.000 32.18328  ? 76  THR A CB  1 
ATOM   1814 O  OG1 . THR B 1 96  ? -8.83231  10.45277  24.55387  1.000 32.34959  ? 76  THR A OG1 1 
ATOM   1815 C  CG2 . THR B 1 96  ? -6.71280  10.28891  23.40723  1.000 25.01474  ? 76  THR A CG2 1 
ATOM   1816 N  N   . LEU B 1 97  ? -7.26831  7.93219   21.05613  1.000 29.68233  ? 77  LEU A N   1 
ATOM   1817 C  CA  . LEU B 1 97  ? -6.36919  7.10636   20.26063  1.000 29.04861  ? 77  LEU A CA  1 
ATOM   1818 C  C   . LEU B 1 97  ? -5.26616  7.99468   19.70741  1.000 31.34301  ? 77  LEU A C   1 
ATOM   1819 O  O   . LEU B 1 97  ? -5.54625  8.95874   18.98619  1.000 35.66389  ? 77  LEU A O   1 
ATOM   1820 C  CB  . LEU B 1 97  ? -7.12738  6.40979   19.13024  1.000 25.47892  ? 77  LEU A CB  1 
ATOM   1821 C  CG  . LEU B 1 97  ? -6.33531  5.44058   18.25596  1.000 36.98734  ? 77  LEU A CG  1 
ATOM   1822 C  CD1 . LEU B 1 97  ? -5.81911  4.27338   19.08321  1.000 34.80431  ? 77  LEU A CD1 1 
ATOM   1823 C  CD2 . LEU B 1 97  ? -7.19346  4.94925   17.10231  1.000 31.22281  ? 77  LEU A CD2 1 
ATOM   1824 N  N   . THR B 1 98  ? -4.01900  7.68223   20.05245  1.000 26.68243  ? 78  THR A N   1 
ATOM   1825 C  CA  . THR B 1 98  ? -2.89518  8.52393   19.66436  1.000 31.34224  ? 78  THR A CA  1 
ATOM   1826 C  C   . THR B 1 98  ? -1.78587  7.68767   19.03964  1.000 31.22336  ? 78  THR A C   1 
ATOM   1827 O  O   . THR B 1 98  ? -1.66319  6.48574   19.28657  1.000 38.31906  ? 78  THR A O   1 
ATOM   1828 C  CB  . THR B 1 98  ? -2.32957  9.30950   20.85997  1.000 28.57407  ? 78  THR A CB  1 
ATOM   1829 O  OG1 . THR B 1 98  ? -1.91121  8.39602   21.88000  1.000 28.50865  ? 78  THR A OG1 1 
ATOM   1830 C  CG2 . THR B 1 98  ? -3.37756  10.26103  21.42816  1.000 26.68201  ? 78  THR A CG2 1 
ATOM   1831 N  N   . TRP B 1 99  ? -0.96983  8.34777   18.21421  1.000 34.96278  ? 79  TRP A N   1 
ATOM   1832 C  CA  . TRP B 1 99  ? 0.21349   7.70590   17.65364  1.000 35.95664  ? 79  TRP A CA  1 
ATOM   1833 C  C   . TRP B 1 99  ? 1.39445   7.72318   18.61307  1.000 36.34729  ? 79  TRP A C   1 
ATOM   1834 O  O   . TRP B 1 99  ? 2.29421   6.88479   18.48410  1.000 40.78847  ? 79  TRP A O   1 
ATOM   1835 C  CB  . TRP B 1 99  ? 0.62062   8.37747   16.34046  1.000 39.62528  ? 79  TRP A CB  1 
ATOM   1836 C  CG  . TRP B 1 99  ? -0.22381  7.98929   15.16413  1.000 38.19497  ? 79  TRP A CG  1 
ATOM   1837 C  CD1 . TRP B 1 99  ? -1.22749  8.71989   14.59855  1.000 40.59507  ? 79  TRP A CD1 1 
ATOM   1838 C  CD2 . TRP B 1 99  ? -0.13294  6.77750   14.40493  1.000 36.89013  ? 79  TRP A CD2 1 
ATOM   1839 N  NE1 . TRP B 1 99  ? -1.77059  8.03705   13.53668  1.000 42.34297  ? 79  TRP A NE1 1 
ATOM   1840 C  CE2 . TRP B 1 99  ? -1.11538  6.84190   13.39637  1.000 42.99754  ? 79  TRP A CE2 1 
ATOM   1841 C  CE3 . TRP B 1 99  ? 0.68214   5.64331   14.48143  1.000 41.06867  ? 79  TRP A CE3 1 
ATOM   1842 C  CZ2 . TRP B 1 99  ? -1.30482  5.81551   12.47118  1.000 46.74621  ? 79  TRP A CZ2 1 
ATOM   1843 C  CZ3 . TRP B 1 99  ? 0.49269   4.62567   13.56188  1.000 47.03435  ? 79  TRP A CZ3 1 
ATOM   1844 C  CH2 . TRP B 1 99  ? -0.49256  4.71890   12.57079  1.000 51.04097  ? 79  TRP A CH2 1 
ATOM   1845 N  N   . ASP B 1 100 ? 1.41218   8.66515   19.57421  1.000 33.00801  ? 80  ASP A N   1 
ATOM   1846 C  CA  . ASP B 1 100 ? 2.44351   8.81199   20.58590  1.000 38.29196  ? 80  ASP A CA  1 
ATOM   1847 C  C   . ASP B 1 100 ? 2.00877   8.16558   21.89726  1.000 35.67977  ? 80  ASP A C   1 
ATOM   1848 O  O   . ASP B 1 100 ? 0.81375   8.11769   22.20746  1.000 35.42499  ? 80  ASP A O   1 
ATOM   1849 C  CB  . ASP B 1 100 ? 2.75650   10.29332  20.83058  1.000 37.13685  ? 80  ASP A CB  1 
ATOM   1850 C  CG  . ASP B 1 100 ? 1.51979   11.10478  21.17927  1.000 51.25972  ? 80  ASP A CG  1 
ATOM   1851 O  OD1 . ASP B 1 100 ? 0.52465   11.03166  20.42568  1.000 47.94495  ? 80  ASP A OD1 1 
ATOM   1852 O  OD2 . ASP B 1 100 ? 1.54212   11.81391  22.20902  1.000 60.37158  ? 80  ASP A OD2 1 
ATOM   1853 N  N   . PRO B 1 101 ? 2.95429   7.65637   22.68318  1.000 38.41792  ? 81  PRO A N   1 
ATOM   1854 C  CA  . PRO B 1 101 ? 2.60500   7.03720   23.96870  1.000 40.18056  ? 81  PRO A CA  1 
ATOM   1855 C  C   . PRO B 1 101 ? 2.10029   8.07315   24.95548  1.000 31.68176  ? 81  PRO A C   1 
ATOM   1856 O  O   . PRO B 1 101 ? 2.76585   9.08966   25.20200  1.000 35.03220  ? 81  PRO A O   1 
ATOM   1857 C  CB  . PRO B 1 101 ? 3.93278   6.42332   24.44438  1.000 37.14269  ? 81  PRO A CB  1 
ATOM   1858 C  CG  . PRO B 1 101 ? 4.81275   6.39041   23.23004  1.000 32.93860  ? 81  PRO A CG  1 
ATOM   1859 C  CD  . PRO B 1 101 ? 4.39140   7.54539   22.38753  1.000 36.29733  ? 81  PRO A CD  1 
ATOM   1860 N  N   . PRO B 1 102 ? 0.92320   7.85413   25.54064  1.000 34.21979  ? 82  PRO A N   1 
ATOM   1861 C  CA  . PRO B 1 102 ? 0.42982   8.72625   26.61519  1.000 31.49837  ? 82  PRO A CA  1 
ATOM   1862 C  C   . PRO B 1 102 ? 0.91849   8.35273   28.00762  1.000 32.13826  ? 82  PRO A C   1 
ATOM   1863 O  O   . PRO B 1 102 ? 0.42493   8.92290   28.98461  1.000 35.96153  ? 82  PRO A O   1 
ATOM   1864 C  CB  . PRO B 1 102 ? -1.08839  8.52933   26.51351  1.000 32.72100  ? 82  PRO A CB  1 
ATOM   1865 C  CG  . PRO B 1 102 ? -1.22725  7.09857   26.10946  1.000 32.08144  ? 82  PRO A CG  1 
ATOM   1866 C  CD  . PRO B 1 102 ? -0.04641  6.79683   25.20653  1.000 30.65599  ? 82  PRO A CD  1 
ATOM   1867 N  N   . PHE B 1 103 ? 1.85276   7.41079   28.11875  1.000 38.25746  ? 83  PHE A N   1 
ATOM   1868 C  CA  . PHE B 1 103 ? 2.43890   7.02093   29.39107  1.000 36.34059  ? 83  PHE A CA  1 
ATOM   1869 C  C   . PHE B 1 103 ? 3.95294   6.96799   29.23997  1.000 41.27809  ? 83  PHE A C   1 
ATOM   1870 O  O   . PHE B 1 103 ? 4.49050   6.96511   28.12866  1.000 44.61339  ? 83  PHE A O   1 
ATOM   1871 C  CB  . PHE B 1 103 ? 1.88933   5.67174   29.88172  1.000 35.89330  ? 83  PHE A CB  1 
ATOM   1872 C  CG  . PHE B 1 103 ? 1.79713   4.61763   28.81099  1.000 35.25724  ? 83  PHE A CG  1 
ATOM   1873 C  CD1 . PHE B 1 103 ? 2.93863   4.07528   28.24317  1.000 38.25207  ? 83  PHE A CD1 1 
ATOM   1874 C  CD2 . PHE B 1 103 ? 0.56202   4.16380   28.38108  1.000 33.07764  ? 83  PHE A CD2 1 
ATOM   1875 C  CE1 . PHE B 1 103 ? 2.84912   3.11157   27.25517  1.000 42.67768  ? 83  PHE A CE1 1 
ATOM   1876 C  CE2 . PHE B 1 103 ? 0.46688   3.19689   27.39634  1.000 31.37956  ? 83  PHE A CE2 1 
ATOM   1877 C  CZ  . PHE B 1 103 ? 1.61065   2.67025   26.83302  1.000 30.37539  ? 83  PHE A CZ  1 
ATOM   1878 N  N   . ALA B 1 104 ? 4.64329   6.90993   30.37645  1.000 36.34554  ? 84  ALA A N   1 
ATOM   1879 C  CA  . ALA B 1 104 ? 6.09907   6.95600   30.40891  1.000 43.10191  ? 84  ALA A CA  1 
ATOM   1880 C  C   . ALA B 1 104 ? 6.74008   5.57500   30.48828  1.000 39.82428  ? 84  ALA A C   1 
ATOM   1881 O  O   . ALA B 1 104 ? 7.96023   5.48131   30.65091  1.000 37.30992  ? 84  ALA A O   1 
ATOM   1882 C  CB  . ALA B 1 104 ? 6.56958   7.81238   31.58868  1.000 42.82599  ? 84  ALA A CB  1 
ATOM   1883 N  N   . ALA B 1 105 ? 5.95216   4.50862   30.37053  1.000 36.05998  ? 85  ALA A N   1 
ATOM   1884 C  CA  . ALA B 1 105 ? 6.47786   3.15930   30.51234  1.000 36.50808  ? 85  ALA A CA  1 
ATOM   1885 C  C   . ALA B 1 105 ? 7.52121   2.86115   29.44043  1.000 46.67084  ? 85  ALA A C   1 
ATOM   1886 O  O   . ALA B 1 105 ? 7.53421   3.45895   28.36102  1.000 44.68506  ? 85  ALA A O   1 
ATOM   1887 C  CB  . ALA B 1 105 ? 5.35152   2.13248   30.42998  1.000 34.42823  ? 85  ALA A CB  1 
ATOM   1888 N  N   . ASP B 1 106 ? 8.40536   1.91451   29.75463  1.000 44.73362  ? 86  ASP A N   1 
ATOM   1889 C  CA  . ASP B 1 106 ? 9.39779   1.44272   28.79806  1.000 40.05355  ? 86  ASP A CA  1 
ATOM   1890 C  C   . ASP B 1 106 ? 8.73313   0.47743   27.82552  1.000 48.51819  ? 86  ASP A C   1 
ATOM   1891 O  O   . ASP B 1 106 ? 8.24460   -0.58355  28.22922  1.000 50.34297  ? 86  ASP A O   1 
ATOM   1892 C  CB  . ASP B 1 106 ? 10.56337  0.77380   29.52108  1.000 43.57902  ? 86  ASP A CB  1 
ATOM   1893 C  CG  . ASP B 1 106 ? 11.48076  0.02540   28.57455  1.000 42.28513  ? 86  ASP A CG  1 
ATOM   1894 O  OD1 . ASP B 1 106 ? 11.86508  0.60117   27.53437  1.000 42.79220  ? 86  ASP A OD1 1 
ATOM   1895 O  OD2 . ASP B 1 106 ? 11.82501  -1.13633  28.87601  1.000 51.19501  ? 86  ASP A OD2 1 
ATOM   1896 N  N   . GLU B 1 107 ? 8.71743   0.84482   26.54420  1.000 46.53587  ? 87  GLU A N   1 
ATOM   1897 C  CA  . GLU B 1 107 ? 8.01412   0.05732   25.54108  1.000 50.34265  ? 87  GLU A CA  1 
ATOM   1898 C  C   . GLU B 1 107 ? 8.73420   -1.23450  25.18267  1.000 51.08021  ? 87  GLU A C   1 
ATOM   1899 O  O   . GLU B 1 107 ? 8.14152   -2.08181  24.50614  1.000 53.98043  ? 87  GLU A O   1 
ATOM   1900 C  CB  . GLU B 1 107 ? 7.80280   0.89668   24.28526  1.000 52.70241  ? 87  GLU A CB  1 
ATOM   1901 C  CG  . GLU B 1 107 ? 7.32760   2.30468   24.57596  1.000 56.12936  ? 87  GLU A CG  1 
ATOM   1902 C  CD  . GLU B 1 107 ? 6.14703   2.69512   23.72256  1.000 53.52876  ? 87  GLU A CD  1 
ATOM   1903 O  OE1 . GLU B 1 107 ? 5.08392   2.05242   23.85018  1.000 41.14163  ? 87  GLU A OE1 1 
ATOM   1904 O  OE2 . GLU B 1 107 ? 6.28456   3.63082   22.90780  1.000 54.87870  ? 87  GLU A OE2 1 
ATOM   1905 N  N   . GLY B 1 108 ? 9.98593   -1.40748  25.61244  1.000 58.16377  ? 88  GLY A N   1 
ATOM   1906 C  CA  . GLY B 1 108 ? 10.68667  -2.65553  25.36770  1.000 53.29597  ? 88  GLY A CA  1 
ATOM   1907 C  C   . GLY B 1 108 ? 10.02645  -3.85977  26.00494  1.000 60.18457  ? 88  GLY A C   1 
ATOM   1908 O  O   . GLY B 1 108 ? 10.29442  -4.99446  25.59341  1.000 57.19407  ? 88  GLY A O   1 
ATOM   1909 N  N   . ALA B 1 109 ? 9.16593   -3.63961  27.00292  1.000 62.41483  ? 89  ALA A N   1 
ATOM   1910 C  CA  . ALA B 1 109 ? 8.43512   -4.74713  27.60849  1.000 60.70025  ? 89  ALA A CA  1 
ATOM   1911 C  C   . ALA B 1 109 ? 7.38642   -5.30520  26.65372  1.000 51.42158  ? 89  ALA A C   1 
ATOM   1912 O  O   . ALA B 1 109 ? 7.13233   -6.51520  26.64158  1.000 47.86060  ? 89  ALA A O   1 
ATOM   1913 C  CB  . ALA B 1 109 ? 7.78709   -4.29468  28.91726  1.000 44.68266  ? 89  ALA A CB  1 
ATOM   1914 N  N   . PHE B 1 110 ? 6.76712   -4.44211  25.85015  1.000 50.51544  ? 90  PHE A N   1 
ATOM   1915 C  CA  . PHE B 1 110 ? 5.76253   -4.88555  24.90032  1.000 47.94715  ? 90  PHE A CA  1 
ATOM   1916 C  C   . PHE B 1 110 ? 6.39971   -5.72558  23.79617  1.000 49.60165  ? 90  PHE A C   1 
ATOM   1917 O  O   . PHE B 1 110 ? 7.59802   -5.60878  23.52539  1.000 55.54985  ? 90  PHE A O   1 
ATOM   1918 C  CB  . PHE B 1 110 ? 5.04324   -3.69066  24.27573  1.000 49.03807  ? 90  PHE A CB  1 
ATOM   1919 C  CG  . PHE B 1 110 ? 4.25145   -2.86950  25.25144  1.000 46.24399  ? 90  PHE A CG  1 
ATOM   1920 C  CD1 . PHE B 1 110 ? 3.27267   -3.45382  26.03981  1.000 49.78583  ? 90  PHE A CD1 1 
ATOM   1921 C  CD2 . PHE B 1 110 ? 4.46494   -1.50518  25.35847  1.000 36.97918  ? 90  PHE A CD2 1 
ATOM   1922 C  CE1 . PHE B 1 110 ? 2.53370   -2.69306  26.92932  1.000 39.87403  ? 90  PHE A CE1 1 
ATOM   1923 C  CE2 . PHE B 1 110 ? 3.72962   -0.74273  26.24234  1.000 45.76959  ? 90  PHE A CE2 1 
ATOM   1924 C  CZ  . PHE B 1 110 ? 2.76362   -1.33626  27.02726  1.000 38.34424  ? 90  PHE A CZ  1 
ATOM   1925 N  N   . PRO B 1 111 ? 5.62130   -6.58864  23.14913  1.000 52.25825  ? 91  PRO A N   1 
ATOM   1926 C  CA  . PRO B 1 111 ? 6.11560   -7.25600  21.95397  1.000 53.36321  ? 91  PRO A CA  1 
ATOM   1927 C  C   . PRO B 1 111 ? 6.43907   -6.23015  20.87646  1.000 48.13999  ? 91  PRO A C   1 
ATOM   1928 O  O   . PRO B 1 111 ? 5.83070   -5.14678  20.83166  1.000 49.96294  ? 91  PRO A O   1 
ATOM   1929 C  CB  . PRO B 1 111 ? 4.94966   -8.16006  21.53820  1.000 42.22856  ? 91  PRO A CB  1 
ATOM   1930 C  CG  . PRO B 1 111 ? 4.17160   -8.37069  22.78764  1.000 42.44034  ? 91  PRO A CG  1 
ATOM   1931 C  CD  . PRO B 1 111 ? 4.29183   -7.08678  23.54754  1.000 42.30248  ? 91  PRO A CD  1 
ATOM   1932 N  N   . PRO B 1 112 ? 7.39551   -6.53301  20.00376  1.000 58.30115  ? 92  PRO A N   1 
ATOM   1933 C  CA  . PRO B 1 112 ? 7.79360   -5.55188  18.98569  1.000 44.94244  ? 92  PRO A CA  1 
ATOM   1934 C  C   . PRO B 1 112 ? 6.63345   -5.18623  18.07220  1.000 46.14465  ? 92  PRO A C   1 
ATOM   1935 O  O   . PRO B 1 112 ? 5.81104   -6.02979  17.70862  1.000 50.07625  ? 92  PRO A O   1 
ATOM   1936 C  CB  . PRO B 1 112 ? 8.90877   -6.27141  18.21779  1.000 52.24735  ? 92  PRO A CB  1 
ATOM   1937 C  CG  . PRO B 1 112 ? 9.42699   -7.29682  19.17484  1.000 56.39589  ? 92  PRO A CG  1 
ATOM   1938 C  CD  . PRO B 1 112 ? 8.23166   -7.74365  19.96298  1.000 49.17924  ? 92  PRO A CD  1 
ATOM   1939 N  N   . ALA B 1 113 ? 6.57215   -3.90791  17.70878  1.000 40.87438  ? 93  ALA A N   1 
ATOM   1940 C  CA  . ALA B 1 113 ? 5.54039   -3.41381  16.81104  1.000 40.26344  ? 93  ALA A CA  1 
ATOM   1941 C  C   . ALA B 1 113 ? 6.11075   -2.25805  16.00464  1.000 44.96233  ? 93  ALA A C   1 
ATOM   1942 O  O   . ALA B 1 113 ? 6.88130   -1.45032  16.52811  1.000 49.76931  ? 93  ALA A O   1 
ATOM   1943 C  CB  . ALA B 1 113 ? 4.28852   -2.96879  17.57669  1.000 45.27802  ? 93  ALA A CB  1 
ATOM   1944 N  N   . GLU B 1 114 ? 5.73793   -2.19095  14.72689  1.000 54.81652  ? 94  GLU A N   1 
ATOM   1945 C  CA  . GLU B 1 114 ? 6.23834   -1.13566  13.85417  1.000 55.38414  ? 94  GLU A CA  1 
ATOM   1946 C  C   . GLU B 1 114 ? 5.35846   0.10908   13.89720  1.000 42.93806  ? 94  GLU A C   1 
ATOM   1947 O  O   . GLU B 1 114 ? 5.87145   1.23011   13.97812  1.000 53.35839  ? 94  GLU A O   1 
ATOM   1948 C  CB  . GLU B 1 114 ? 6.36523   -1.63871  12.41390  1.000 56.18736  ? 94  GLU A CB  1 
ATOM   1949 C  CG  . GLU B 1 114 ? 7.52892   -2.57393  12.16743  1.000 47.03076  ? 94  GLU A CG  1 
ATOM   1950 C  CD  . GLU B 1 114 ? 7.91695   -2.62459  10.70167  1.000 72.83469  ? 94  GLU A CD  1 
ATOM   1951 O  OE1 . GLU B 1 114 ? 8.65624   -1.72305  10.24944  1.000 71.20123  ? 94  GLU A OE1 1 
ATOM   1952 O  OE2 . GLU B 1 114 ? 7.46545   -3.55052  9.99454   1.000 75.51897  ? 94  GLU A OE2 1 
ATOM   1953 N  N   . ARG B 1 115 ? 4.03777   -0.06525  13.82351  1.000 49.81132  ? 95  ARG A N   1 
ATOM   1954 C  CA  . ARG B 1 115 ? 3.08316   1.04258   13.82317  1.000 50.50016  ? 95  ARG A CA  1 
ATOM   1955 C  C   . ARG B 1 115 ? 2.09795   0.87399   14.97667  1.000 44.70008  ? 95  ARG A C   1 
ATOM   1956 O  O   . ARG B 1 115 ? 0.90409   0.62761   14.75738  1.000 44.65724  ? 95  ARG A O   1 
ATOM   1957 C  CB  . ARG B 1 115 ? 2.34392   1.12679   12.48856  1.000 58.36223  ? 95  ARG A CB  1 
ATOM   1958 C  CG  . ARG B 1 115 ? 3.25466   1.35868   11.29494  1.000 65.74022  ? 95  ARG A CG  1 
ATOM   1959 C  CD  . ARG B 1 115 ? 2.59578   0.94254   9.98611   1.000 67.56070  ? 95  ARG A CD  1 
ATOM   1960 N  NE  . ARG B 1 115 ? 2.15793   -0.44950  10.00543  1.000 74.53388  ? 95  ARG A NE  1 
ATOM   1961 C  CZ  . ARG B 1 115 ? 2.96934   -1.49582  9.91790   1.000 68.88837  ? 95  ARG A CZ  1 
ATOM   1962 N  NH1 . ARG B 1 115 ? 4.28236   -1.34904  9.83218   1.000 71.09195  ? 95  ARG A NH1 1 
ATOM   1963 N  NH2 . ARG B 1 115 ? 2.45068   -2.72110  9.92234   1.000 67.93138  ? 95  ARG A NH2 1 
ATOM   1964 N  N   . PRO B 1 116 ? 2.56067   1.00496   16.21905  1.000 43.97781  ? 96  PRO A N   1 
ATOM   1965 C  CA  . PRO B 1 116 ? 1.64889   0.84983   17.35500  1.000 41.96262  ? 96  PRO A CA  1 
ATOM   1966 C  C   . PRO B 1 116 ? 0.87118   2.12851   17.61955  1.000 36.74940  ? 96  PRO A C   1 
ATOM   1967 O  O   . PRO B 1 116 ? 1.40705   3.23668   17.54186  1.000 33.00925  ? 96  PRO A O   1 
ATOM   1968 C  CB  . PRO B 1 116 ? 2.59420   0.52514   18.51702  1.000 34.63759  ? 96  PRO A CB  1 
ATOM   1969 C  CG  . PRO B 1 116 ? 3.83333   1.27971   18.17734  1.000 39.38046  ? 96  PRO A CG  1 
ATOM   1970 C  CD  . PRO B 1 116 ? 3.93500   1.30176   16.66395  1.000 45.85050  ? 96  PRO A CD  1 
ATOM   1971 N  N   . LEU B 1 117 ? -0.41288  1.96429   17.91505  1.000 32.95594  ? 97  LEU A N   1 
ATOM   1972 C  CA  . LEU B 1 117 ? -1.25239  3.04864   18.39526  1.000 31.10494  ? 97  LEU A CA  1 
ATOM   1973 C  C   . LEU B 1 117 ? -1.53302  2.84169   19.87567  1.000 32.89262  ? 97  LEU A C   1 
ATOM   1974 O  O   . LEU B 1 117 ? -1.32303  1.75667   20.42511  1.000 33.92712  ? 97  LEU A O   1 
ATOM   1975 C  CB  . LEU B 1 117 ? -2.56424  3.14194   17.60994  1.000 38.96309  ? 97  LEU A CB  1 
ATOM   1976 C  CG  . LEU B 1 117 ? -2.45567  3.79564   16.23056  1.000 44.44734  ? 97  LEU A CG  1 
ATOM   1977 C  CD1 . LEU B 1 117 ? -2.14559  2.75662   15.17593  1.000 40.97612  ? 97  LEU A CD1 1 
ATOM   1978 C  CD2 . LEU B 1 117 ? -3.71914  4.56356   15.87806  1.000 42.74248  ? 97  LEU A CD2 1 
ATOM   1979 N  N   . TYR B 1 118 ? -2.01518  3.89738   20.52170  1.000 32.49918  ? 98  TYR A N   1 
ATOM   1980 C  CA  . TYR B 1 118 ? -2.15308  3.91271   21.96782  1.000 26.67774  ? 98  TYR A CA  1 
ATOM   1981 C  C   . TYR B 1 118 ? -3.56498  4.32309   22.34757  1.000 31.34526  ? 98  TYR A C   1 
ATOM   1982 O  O   . TYR B 1 118 ? -4.08491  5.33212   21.85138  1.000 33.13551  ? 98  TYR A O   1 
ATOM   1983 C  CB  . TYR B 1 118 ? -1.12685  4.85787   22.59421  1.000 27.81086  ? 98  TYR A CB  1 
ATOM   1984 C  CG  . TYR B 1 118 ? 0.29377   4.40634   22.35066  1.000 37.49315  ? 98  TYR A CG  1 
ATOM   1985 C  CD1 . TYR B 1 118 ? 0.94794   4.72433   21.16586  1.000 37.44593  ? 98  TYR A CD1 1 
ATOM   1986 C  CD2 . TYR B 1 118 ? 0.97417   3.64892   23.29175  1.000 28.02531  ? 98  TYR A CD2 1 
ATOM   1987 C  CE1 . TYR B 1 118 ? 2.23827   4.30795   20.93115  1.000 31.02463  ? 98  TYR A CE1 1 
ATOM   1988 C  CE2 . TYR B 1 118 ? 2.27077   3.22871   23.06566  1.000 38.75541  ? 98  TYR A CE2 1 
ATOM   1989 C  CZ  . TYR B 1 118 ? 2.89615   3.56224   21.88234  1.000 33.57653  ? 98  TYR A CZ  1 
ATOM   1990 O  OH  . TYR B 1 118 ? 4.18454   3.15186   21.64014  1.000 34.19129  ? 98  TYR A OH  1 
ATOM   1991 N  N   . LEU B 1 119 ? -4.17113  3.52896   23.22398  1.000 28.77725  ? 99  LEU A N   1 
ATOM   1992 C  CA  . LEU B 1 119 ? -5.51424  3.75786   23.73125  1.000 25.48706  ? 99  LEU A CA  1 
ATOM   1993 C  C   . LEU B 1 119 ? -5.43462  4.30998   25.14826  1.000 33.21111  ? 99  LEU A C   1 
ATOM   1994 O  O   . LEU B 1 119 ? -4.74889  3.73829   26.00342  1.000 28.42332  ? 99  LEU A O   1 
ATOM   1995 C  CB  . LEU B 1 119 ? -6.31490  2.45701   23.71682  1.000 28.02425  ? 99  LEU A CB  1 
ATOM   1996 C  CG  . LEU B 1 119 ? -7.61658  2.45619   24.50933  1.000 33.53390  ? 99  LEU A CG  1 
ATOM   1997 C  CD1 . LEU B 1 119 ? -8.71564  3.12933   23.71541  1.000 22.50933  ? 99  LEU A CD1 1 
ATOM   1998 C  CD2 . LEU B 1 119 ? -7.99343  1.03715   24.87743  1.000 32.80277  ? 99  LEU A CD2 1 
ATOM   1999 N  N   . SER B 1 120 ? -6.13094  5.41957   25.39108  1.000 22.88017  ? 100 SER A N   1 
ATOM   2000 C  CA  . SER B 1 120 ? -6.16199  6.02779   26.71237  1.000 24.66626  ? 100 SER A CA  1 
ATOM   2001 C  C   . SER B 1 120 ? -7.54074  6.62194   26.95779  1.000 30.07247  ? 100 SER A C   1 
ATOM   2002 O  O   . SER B 1 120 ? -8.35072  6.76928   26.03829  1.000 26.30831  ? 100 SER A O   1 
ATOM   2003 C  CB  . SER B 1 120 ? -5.07917  7.10656   26.87076  1.000 29.54102  ? 100 SER A CB  1 
ATOM   2004 O  OG  . SER B 1 120 ? -5.22304  8.14079   25.91080  1.000 26.55625  ? 100 SER A OG  1 
ATOM   2005 N  N   . ARG B 1 121 ? -7.80520  6.93464   28.22636  1.000 29.11342  ? 101 ARG A N   1 
ATOM   2006 C  CA  . ARG B 1 121 ? -8.99974  7.68058   28.62261  1.000 28.55553  ? 101 ARG A CA  1 
ATOM   2007 C  C   . ARG B 1 121 ? -10.28079 7.01876   28.11875  1.000 31.61879  ? 101 ARG A C   1 
ATOM   2008 O  O   . ARG B 1 121 ? -11.20811 7.68558   27.64933  1.000 24.32989  ? 101 ARG A O   1 
ATOM   2009 C  CB  . ARG B 1 121 ? -8.91180  9.12798   28.14232  1.000 25.59833  ? 101 ARG A CB  1 
ATOM   2010 C  CG  . ARG B 1 121 ? -7.80749  9.92887   28.80208  1.000 27.92655  ? 101 ARG A CG  1 
ATOM   2011 C  CD  . ARG B 1 121 ? -7.88127  11.38130  28.37867  1.000 30.01048  ? 101 ARG A CD  1 
ATOM   2012 N  NE  . ARG B 1 121 ? -7.45067  12.28611  29.43571  1.000 30.75130  ? 101 ARG A NE  1 
ATOM   2013 C  CZ  . ARG B 1 121 ? -7.84601  13.54703  29.53523  1.000 36.34825  ? 101 ARG A CZ  1 
ATOM   2014 N  NH1 . ARG B 1 121 ? -8.69379  14.07328  28.66748  1.000 33.30658  ? 101 ARG A NH1 1 
ATOM   2015 N  NH2 . ARG B 1 121 ? -7.39012  14.29456  30.53670  1.000 35.68121  ? 101 ARG A NH2 1 
ATOM   2016 N  N   . LEU B 1 122 ? -10.32255 5.69005   28.19647  1.000 30.62487  ? 102 LEU A N   1 
ATOM   2017 C  CA  . LEU B 1 122 ? -11.56244 4.97114   27.94342  1.000 27.17199  ? 102 LEU A CA  1 
ATOM   2018 C  C   . LEU B 1 122 ? -12.58494 5.35984   29.00044  1.000 30.16892  ? 102 LEU A C   1 
ATOM   2019 O  O   . LEU B 1 122 ? -12.30601 5.29856   30.20170  1.000 38.60748  ? 102 LEU A O   1 
ATOM   2020 C  CB  . LEU B 1 122 ? -11.31313 3.46007   27.96212  1.000 36.64196  ? 102 LEU A CB  1 
ATOM   2021 C  CG  . LEU B 1 122 ? -12.37720 2.47348   27.45397  1.000 38.93639  ? 102 LEU A CG  1 
ATOM   2022 C  CD1 . LEU B 1 122 ? -13.53577 2.29084   28.43477  1.000 42.82618  ? 102 LEU A CD1 1 
ATOM   2023 C  CD2 . LEU B 1 122 ? -12.89396 2.88698   26.08488  1.000 28.44152  ? 102 LEU A CD2 1 
ATOM   2024 N  N   . ALA B 1 123 ? -13.76606 5.77401   28.55196  1.000 30.51235  ? 103 ALA A N   1 
ATOM   2025 C  CA  . ALA B 1 123 ? -14.79974 6.25039   29.45596  1.000 31.31175  ? 103 ALA A CA  1 
ATOM   2026 C  C   . ALA B 1 123 ? -16.16467 5.80081   28.96340  1.000 33.47587  ? 103 ALA A C   1 
ATOM   2027 O  O   . ALA B 1 123 ? -16.44894 5.84551   27.76378  1.000 30.90677  ? 103 ALA A O   1 
ATOM   2028 C  CB  . ALA B 1 123 ? -14.77267 7.77931   29.58793  1.000 35.96099  ? 103 ALA A CB  1 
ATOM   2029 N  N   . VAL B 1 124 ? -17.00057 5.36183   29.89992  1.000 25.31175  ? 104 VAL A N   1 
ATOM   2030 C  CA  . VAL B 1 124 ? -18.38247 4.98751   29.63067  1.000 33.48184  ? 104 VAL A CA  1 
ATOM   2031 C  C   . VAL B 1 124 ? -19.27432 5.78653   30.56940  1.000 32.58308  ? 104 VAL A C   1 
ATOM   2032 O  O   . VAL B 1 124 ? -18.99230 5.87526   31.77066  1.000 25.87571  ? 104 VAL A O   1 
ATOM   2033 C  CB  . VAL B 1 124 ? -18.61632 3.47651   29.82122  1.000 34.18293  ? 104 VAL A CB  1 
ATOM   2034 C  CG1 . VAL B 1 124 ? -20.05038 3.11612   29.46994  1.000 35.18772  ? 104 VAL A CG1 1 
ATOM   2035 C  CG2 . VAL B 1 124 ? -17.63180 2.66739   28.98867  1.000 27.93030  ? 104 VAL A CG2 1 
ATOM   2036 N  N   . ALA B 1 125 ? -20.34136 6.36368   30.02439  1.000 29.00635  ? 105 ALA A N   1 
ATOM   2037 C  CA  . ALA B 1 125 ? -21.26894 7.12966   30.84288  1.000 32.60275  ? 105 ALA A CA  1 
ATOM   2038 C  C   . ALA B 1 125 ? -21.80805 6.26319   31.97968  1.000 30.67762  ? 105 ALA A C   1 
ATOM   2039 O  O   . ALA B 1 125 ? -22.17095 5.10167   31.75635  1.000 30.63312  ? 105 ALA A O   1 
ATOM   2040 C  CB  . ALA B 1 125 ? -22.42327 7.66159   29.99373  1.000 28.04876  ? 105 ALA A CB  1 
ATOM   2041 N  N   . PRO B 1 126 ? -21.86767 6.79155   33.20518  1.000 31.95280  ? 106 PRO A N   1 
ATOM   2042 C  CA  . PRO B 1 126 ? -22.30450 5.97540   34.35159  1.000 35.63449  ? 106 PRO A CA  1 
ATOM   2043 C  C   . PRO B 1 126 ? -23.65560 5.30477   34.17292  1.000 36.02685  ? 106 PRO A C   1 
ATOM   2044 O  O   . PRO B 1 126 ? -23.85812 4.20166   34.69705  1.000 40.65997  ? 106 PRO A O   1 
ATOM   2045 C  CB  . PRO B 1 126 ? -22.32864 6.99060   35.50078  1.000 35.56135  ? 106 PRO A CB  1 
ATOM   2046 C  CG  . PRO B 1 126 ? -21.30279 8.00664   35.11619  1.000 38.35841  ? 106 PRO A CG  1 
ATOM   2047 C  CD  . PRO B 1 126 ? -21.37788 8.11660   33.61844  1.000 29.26643  ? 106 PRO A CD  1 
ATOM   2048 N  N   . GLU B 1 127 ? -24.58758 5.92488   33.44668  1.000 31.57549  ? 107 GLU A N   1 
ATOM   2049 C  CA  . GLU B 1 127 ? -25.87613 5.28552   33.20802  1.000 39.55166  ? 107 GLU A CA  1 
ATOM   2050 C  C   . GLU B 1 127 ? -25.76529 4.04356   32.33032  1.000 45.20428  ? 107 GLU A C   1 
ATOM   2051 O  O   . GLU B 1 127 ? -26.72555 3.26900   32.26230  1.000 37.08640  ? 107 GLU A O   1 
ATOM   2052 C  CB  . GLU B 1 127 ? -26.85974 6.27920   32.58246  1.000 34.74625  ? 107 GLU A CB  1 
ATOM   2053 C  CG  . GLU B 1 127 ? -26.39806 6.89510   31.26989  1.000 43.57440  ? 107 GLU A CG  1 
ATOM   2054 C  CD  . GLU B 1 127 ? -25.77277 8.27048   31.44865  1.000 58.74181  ? 107 GLU A CD  1 
ATOM   2055 O  OE1 . GLU B 1 127 ? -24.95265 8.44709   32.37708  1.000 45.93396  ? 107 GLU A OE1 1 
ATOM   2056 O  OE2 . GLU B 1 127 ? -26.10820 9.17915   30.65853  1.000 53.71206  ? 107 GLU A OE2 1 
ATOM   2057 N  N   . TRP B 1 128 ? -24.63198 3.83440   31.66235  1.000 38.59890  ? 108 TRP A N   1 
ATOM   2058 C  CA  . TRP B 1 128 ? -24.39581 2.62364   30.88876  1.000 48.33690  ? 108 TRP A CA  1 
ATOM   2059 C  C   . TRP B 1 128 ? -23.45986 1.65192   31.59122  1.000 46.33991  ? 108 TRP A C   1 
ATOM   2060 O  O   . TRP B 1 128 ? -23.10524 0.62421   31.00774  1.000 47.67403  ? 108 TRP A O   1 
ATOM   2061 C  CB  . TRP B 1 128 ? -23.83424 2.97267   29.50737  1.000 38.32506  ? 108 TRP A CB  1 
ATOM   2062 C  CG  . TRP B 1 128 ? -24.75158 3.82515   28.68966  1.000 42.81993  ? 108 TRP A CG  1 
ATOM   2063 C  CD1 . TRP B 1 128 ? -24.59564 5.14778   28.39546  1.000 44.27177  ? 108 TRP A CD1 1 
ATOM   2064 C  CD2 . TRP B 1 128 ? -25.97715 3.41804   28.06904  1.000 44.19707  ? 108 TRP A CD2 1 
ATOM   2065 N  NE1 . TRP B 1 128 ? -25.64378 5.58874   27.62527  1.000 40.29395  ? 108 TRP A NE1 1 
ATOM   2066 C  CE2 . TRP B 1 128 ? -26.50635 4.54617   27.41179  1.000 48.00861  ? 108 TRP A CE2 1 
ATOM   2067 C  CE3 . TRP B 1 128 ? -26.67678 2.20858   28.00259  1.000 48.21760  ? 108 TRP A CE3 1 
ATOM   2068 C  CZ2 . TRP B 1 128 ? -27.70141 4.50178   26.69771  1.000 49.27762  ? 108 TRP A CZ2 1 
ATOM   2069 C  CZ3 . TRP B 1 128 ? -27.86398 2.16663   27.29228  1.000 48.60997  ? 108 TRP A CZ3 1 
ATOM   2070 C  CH2 . TRP B 1 128 ? -28.36414 3.30622   26.64945  1.000 51.19256  ? 108 TRP A CH2 1 
ATOM   2071 N  N   . LEU B 1 129 ? -23.04991 1.95257   32.82224  1.000 48.93952  ? 109 LEU A N   1 
ATOM   2072 C  CA  . LEU B 1 129 ? -22.18049 1.06470   33.59366  1.000 48.82214  ? 109 LEU A CA  1 
ATOM   2073 C  C   . LEU B 1 129 ? -23.01852 0.05926   34.38551  1.000 50.72864  ? 109 LEU A C   1 
ATOM   2074 O  O   . LEU B 1 129 ? -22.96488 -0.02776  35.61189  1.000 56.60817  ? 109 LEU A O   1 
ATOM   2075 C  CB  . LEU B 1 129 ? -21.26985 1.88031   34.50470  1.000 43.15727  ? 109 LEU A CB  1 
ATOM   2076 C  CG  . LEU B 1 129 ? -20.17956 2.67569   33.78236  1.000 44.41241  ? 109 LEU A CG  1 
ATOM   2077 C  CD1 . LEU B 1 129 ? -19.34058 3.48877   34.75542  1.000 41.33644  ? 109 LEU A CD1 1 
ATOM   2078 C  CD2 . LEU B 1 129 ? -19.30036 1.73956   32.97182  1.000 39.95154  ? 109 LEU A CD2 1 
ATOM   2079 N  N   . THR B 1 130 ? -23.80863 -0.70842  33.64370  1.000 58.89525  ? 110 THR A N   1 
ATOM   2080 C  CA  . THR B 1 130 ? -24.69847 -1.71066  34.20481  1.000 65.88370  ? 110 THR A CA  1 
ATOM   2081 C  C   . THR B 1 130 ? -24.23418 -3.10596  33.80685  1.000 66.08504  ? 110 THR A C   1 
ATOM   2082 O  O   . THR B 1 130 ? -23.41545 -3.27852  32.89987  1.000 66.11811  ? 110 THR A O   1 
ATOM   2083 C  CB  . THR B 1 130 ? -26.14033 -1.48140  33.73858  1.000 58.70133  ? 110 THR A CB  1 
ATOM   2084 O  OG1 . THR B 1 130 ? -26.19828 -1.54565  32.30837  1.000 52.77961  ? 110 THR A OG1 1 
ATOM   2085 C  CG2 . THR B 1 130 ? -26.62823 -0.11589  34.19311  1.000 50.66529  ? 110 THR A CG2 1 
ATOM   2086 N  N   . GLY B 1 131 ? -24.76545 -4.10507  34.50790  1.000 61.93090  ? 111 GLY A N   1 
ATOM   2087 C  CA  . GLY B 1 131 ? -24.42506 -5.48786  34.23747  1.000 67.08178  ? 111 GLY A CA  1 
ATOM   2088 C  C   . GLY B 1 131 ? -24.84470 -5.94204  32.85415  1.000 72.81634  ? 111 GLY A C   1 
ATOM   2089 O  O   . GLY B 1 131 ? -25.97870 -5.69841  32.42849  1.000 66.75866  ? 111 GLY A O   1 
ATOM   2090 N  N   . GLY B 1 132 ? -23.93375 -6.60091  32.13967  1.000 69.16929  ? 112 GLY A N   1 
ATOM   2091 C  CA  . GLY B 1 132 ? -24.19214 -7.04591  30.78702  1.000 59.87934  ? 112 GLY A CA  1 
ATOM   2092 C  C   . GLY B 1 132 ? -24.17897 -5.96091  29.73328  1.000 65.91006  ? 112 GLY A C   1 
ATOM   2093 O  O   . GLY B 1 132 ? -24.35991 -6.27123  28.54765  1.000 60.12735  ? 112 GLY A O   1 
ATOM   2094 N  N   . SER B 1 133 ? -23.97808 -4.70430  30.12201  1.000 60.45385  ? 113 SER A N   1 
ATOM   2095 C  CA  . SER B 1 133 ? -23.91837 -3.61490  29.15847  1.000 48.69496  ? 113 SER A CA  1 
ATOM   2096 C  C   . SER B 1 133 ? -22.71670 -3.77998  28.23797  1.000 54.35024  ? 113 SER A C   1 
ATOM   2097 O  O   . SER B 1 133 ? -21.64047 -4.21194  28.66110  1.000 55.38467  ? 113 SER A O   1 
ATOM   2098 C  CB  . SER B 1 133 ? -23.84428 -2.27119  29.87979  1.000 46.79288  ? 113 SER A CB  1 
ATOM   2099 O  OG  . SER B 1 133 ? -23.71741 -1.19738  28.96132  1.000 41.62809  ? 113 SER A OG  1 
ATOM   2100 N  N   . LEU B 1 134 ? -22.90441 -3.42575  26.96740  1.000 44.29293  ? 114 LEU A N   1 
ATOM   2101 C  CA  . LEU B 1 134 ? -21.87826 -3.60898  25.95052  1.000 43.18659  ? 114 LEU A CA  1 
ATOM   2102 C  C   . LEU B 1 134 ? -21.31414 -2.28747  25.44051  1.000 37.75881  ? 114 LEU A C   1 
ATOM   2103 O  O   . LEU B 1 134 ? -20.66344 -2.26621  24.39100  1.000 38.73272  ? 114 LEU A O   1 
ATOM   2104 C  CB  . LEU B 1 134 ? -22.43315 -4.43195  24.78652  1.000 45.78759  ? 114 LEU A CB  1 
ATOM   2105 C  CG  . LEU B 1 134 ? -22.94701 -5.83366  25.13190  1.000 44.94125  ? 114 LEU A CG  1 
ATOM   2106 C  CD1 . LEU B 1 134 ? -23.35669 -6.57565  23.86935  1.000 50.44732  ? 114 LEU A CD1 1 
ATOM   2107 C  CD2 . LEU B 1 134 ? -21.90057 -6.62024  25.90322  1.000 37.18120  ? 114 LEU A CD2 1 
ATOM   2108 N  N   . VAL B 1 135 ? -21.54558 -1.18624  26.16103  1.000 39.07356  ? 115 VAL A N   1 
ATOM   2109 C  CA  . VAL B 1 135 ? -21.04809 0.11140   25.71240  1.000 38.85998  ? 115 VAL A CA  1 
ATOM   2110 C  C   . VAL B 1 135 ? -19.52439 0.15127   25.76519  1.000 38.43262  ? 115 VAL A C   1 
ATOM   2111 O  O   . VAL B 1 135 ? -18.86985 0.64668   24.83802  1.000 33.47119  ? 115 VAL A O   1 
ATOM   2112 C  CB  . VAL B 1 135 ? -21.68365 1.23694   26.54755  1.000 38.97621  ? 115 VAL A CB  1 
ATOM   2113 C  CG1 . VAL B 1 135 ? -21.21793 2.59685   26.04708  1.000 30.15267  ? 115 VAL A CG1 1 
ATOM   2114 C  CG2 . VAL B 1 135 ? -23.20000 1.13590   26.48489  1.000 33.48608  ? 115 VAL A CG2 1 
ATOM   2115 N  N   . GLY B 1 136 ? -18.93421 -0.36710  26.84450  1.000 33.65493  ? 116 GLY A N   1 
ATOM   2116 C  CA  . GLY B 1 136 ? -17.48603 -0.49155  26.88702  1.000 33.13484  ? 116 GLY A CA  1 
ATOM   2117 C  C   . GLY B 1 136 ? -16.95397 -1.37001  25.77142  1.000 39.66996  ? 116 GLY A C   1 
ATOM   2118 O  O   . GLY B 1 136 ? -15.91748 -1.07053  25.16875  1.000 31.05606  ? 116 GLY A O   1 
ATOM   2119 N  N   . LEU B 1 137 ? -17.66300 -2.46324  25.47511  1.000 36.83707  ? 117 LEU A N   1 
ATOM   2120 C  CA  . LEU B 1 137 ? -17.28980 -3.29924  24.34076  1.000 32.64478  ? 117 LEU A CA  1 
ATOM   2121 C  C   . LEU B 1 137 ? -17.38863 -2.52415  23.03435  1.000 30.14781  ? 117 LEU A C   1 
ATOM   2122 O  O   . LEU B 1 137 ? -16.52494 -2.66140  22.16420  1.000 32.13005  ? 117 LEU A O   1 
ATOM   2123 C  CB  . LEU B 1 137 ? -18.16537 -4.55122  24.29242  1.000 33.58382  ? 117 LEU A CB  1 
ATOM   2124 C  CG  . LEU B 1 137 ? -17.92234 -5.47398  23.09405  1.000 34.90054  ? 117 LEU A CG  1 
ATOM   2125 C  CD1 . LEU B 1 137 ? -16.49912 -6.01489  23.09962  1.000 29.13033  ? 117 LEU A CD1 1 
ATOM   2126 C  CD2 . LEU B 1 137 ? -18.93233 -6.61070  23.06874  1.000 33.36557  ? 117 LEU A CD2 1 
ATOM   2127 N  N   . ARG B 1 138 ? -18.42989 -1.69971  22.87953  1.000 31.07239  ? 118 ARG A N   1 
ATOM   2128 C  CA  . ARG B 1 138 ? -18.53881 -0.86524  21.68506  1.000 31.07893  ? 118 ARG A CA  1 
ATOM   2129 C  C   . ARG B 1 138 ? -17.33423 0.05867   21.55427  1.000 33.00837  ? 118 ARG A C   1 
ATOM   2130 O  O   . ARG B 1 138 ? -16.74611 0.18471   20.47354  1.000 31.27518  ? 118 ARG A O   1 
ATOM   2131 C  CB  . ARG B 1 138 ? -19.83247 -0.04777  21.71738  1.000 28.45001  ? 118 ARG A CB  1 
ATOM   2132 C  CG  . ARG B 1 138 ? -21.10974 -0.86223  21.59172  1.000 35.44973  ? 118 ARG A CG  1 
ATOM   2133 C  CD  . ARG B 1 138 ? -22.33959 0.03125   21.69689  1.000 40.34397  ? 118 ARG A CD  1 
ATOM   2134 N  NE  . ARG B 1 138 ? -23.58594 -0.72748  21.68610  1.000 47.85245  ? 118 ARG A NE  1 
ATOM   2135 C  CZ  . ARG B 1 138 ? -24.30895 -0.96944  20.60047  1.000 48.60824  ? 118 ARG A CZ  1 
ATOM   2136 N  NH1 . ARG B 1 138 ? -23.93379 -0.53478  19.40800  1.000 44.62734  ? 118 ARG A NH1 1 
ATOM   2137 N  NH2 . ARG B 1 138 ? -25.43843 -1.66274  20.71425  1.000 55.40598  ? 118 ARG A NH2 1 
ATOM   2138 N  N   . CYS B 1 139 ? -16.94992 0.71214   22.65314  1.000 34.31317  ? 119 CYS A N   1 
ATOM   2139 C  CA  . CYS B 1 139 ? -15.83551 1.65317   22.60215  1.000 30.86521  ? 119 CYS A CA  1 
ATOM   2140 C  C   . CYS B 1 139 ? -14.53257 0.94067   22.26036  1.000 27.57354  ? 119 CYS A C   1 
ATOM   2141 O  O   . CYS B 1 139 ? -13.76527 1.40043   21.40628  1.000 28.60496  ? 119 CYS A O   1 
ATOM   2142 C  CB  . CYS B 1 139 ? -15.71034 2.39912   23.93224  1.000 33.74264  ? 119 CYS A CB  1 
ATOM   2143 S  SG  . CYS B 1 139 ? -17.13823 3.41475   24.38897  1.000 32.54987  ? 119 CYS A SG  1 
ATOM   2144 N  N   . LEU B 1 140 ? -14.26970 -0.19434  22.91346  1.000 34.52962  ? 120 LEU A N   1 
ATOM   2145 C  CA  . LEU B 1 140 ? -13.03235 -0.92459  22.65218  1.000 30.86938  ? 120 LEU A CA  1 
ATOM   2146 C  C   . LEU B 1 140 ? -13.00390 -1.48962  21.23571  1.000 34.46420  ? 120 LEU A C   1 
ATOM   2147 O  O   . LEU B 1 140 ? -11.95342 -1.48509  20.58308  1.000 32.52031  ? 120 LEU A O   1 
ATOM   2148 C  CB  . LEU B 1 140 ? -12.85131 -2.03262  23.68760  1.000 28.30679  ? 120 LEU A CB  1 
ATOM   2149 C  CG  . LEU B 1 140 ? -12.23862 -1.57230  25.01156  1.000 42.70742  ? 120 LEU A CG  1 
ATOM   2150 C  CD1 . LEU B 1 140 ? -12.27933 -2.67404  26.05075  1.000 36.82898  ? 120 LEU A CD1 1 
ATOM   2151 C  CD2 . LEU B 1 140 ? -10.80866 -1.11622  24.78516  1.000 42.14669  ? 120 LEU A CD2 1 
ATOM   2152 N  N   . ARG B 1 141 ? -14.14533 -1.97633  20.73998  1.000 36.51467  ? 121 ARG A N   1 
ATOM   2153 C  CA  . ARG B 1 141 ? -14.21781 -2.45684  19.36451  1.000 34.72995  ? 121 ARG A CA  1 
ATOM   2154 C  C   . ARG B 1 141 ? -13.95755 -1.33051  18.37399  1.000 34.39902  ? 121 ARG A C   1 
ATOM   2155 O  O   . ARG B 1 141 ? -13.23538 -1.51668  17.38656  1.000 34.12488  ? 121 ARG A O   1 
ATOM   2156 C  CB  . ARG B 1 141 ? -15.58404 -3.09589  19.10990  1.000 29.68439  ? 121 ARG A CB  1 
ATOM   2157 C  CG  . ARG B 1 141 ? -15.70025 -4.53100  19.59906  1.000 30.34184  ? 121 ARG A CG  1 
ATOM   2158 C  CD  . ARG B 1 141 ? -14.94670 -5.46186  18.66740  1.000 27.38580  ? 121 ARG A CD  1 
ATOM   2159 N  NE  . ARG B 1 141 ? -15.45422 -5.33858  17.30644  1.000 32.54008  ? 121 ARG A NE  1 
ATOM   2160 C  CZ  . ARG B 1 141 ? -14.74827 -5.58736  16.21248  1.000 39.42248  ? 121 ARG A CZ  1 
ATOM   2161 N  NH1 . ARG B 1 141 ? -13.49078 -5.99572  16.27743  1.000 41.06089  ? 121 ARG A NH1 1 
ATOM   2162 N  NH2 . ARG B 1 141 ? -15.31514 -5.41132  15.02286  1.000 45.05226  ? 121 ARG A NH2 1 
ATOM   2163 N  N   . ARG B 1 142 ? -14.53808 -0.15301  18.62103  1.000 29.43612  ? 122 ARG A N   1 
ATOM   2164 C  CA  . ARG B 1 142 ? -14.27722 0.99358   17.75925  1.000 29.05359  ? 122 ARG A CA  1 
ATOM   2165 C  C   . ARG B 1 142 ? -12.80379 1.37828   17.79053  1.000 36.68988  ? 122 ARG A C   1 
ATOM   2166 O  O   . ARG B 1 142 ? -12.22366 1.72245   16.75550  1.000 33.28191  ? 122 ARG A O   1 
ATOM   2167 C  CB  . ARG B 1 142 ? -15.15185 2.17110   18.18274  1.000 28.84410  ? 122 ARG A CB  1 
ATOM   2168 C  CG  . ARG B 1 142 ? -14.96007 3.42577   17.35304  1.000 37.53983  ? 122 ARG A CG  1 
ATOM   2169 C  CD  . ARG B 1 142 ? -15.62153 3.29809   15.99569  1.000 32.92258  ? 122 ARG A CD  1 
ATOM   2170 N  NE  . ARG B 1 142 ? -15.66744 4.58160   15.30611  1.000 41.27006  ? 122 ARG A NE  1 
ATOM   2171 C  CZ  . ARG B 1 142 ? -16.38438 4.82045   14.21709  1.000 40.41166  ? 122 ARG A CZ  1 
ATOM   2172 N  NH1 . ARG B 1 142 ? -17.13312 3.88088   13.66263  1.000 43.94767  ? 122 ARG A NH1 1 
ATOM   2173 N  NH2 . ARG B 1 142 ? -16.35180 6.03284   13.67250  1.000 38.40367  ? 122 ARG A NH2 1 
ATOM   2174 N  N   . ALA B 1 143 ? -12.17864 1.31836   18.96951  1.000 35.59914  ? 123 ALA A N   1 
ATOM   2175 C  CA  . ALA B 1 143 ? -10.75532 1.63067   19.06276  1.000 34.72736  ? 123 ALA A CA  1 
ATOM   2176 C  C   . ALA B 1 143 ? -9.91897  0.63370   18.26867  1.000 30.59769  ? 123 ALA A C   1 
ATOM   2177 O  O   . ALA B 1 143 ? -9.00432  1.02612   17.53363  1.000 34.02483  ? 123 ALA A O   1 
ATOM   2178 C  CB  . ALA B 1 143 ? -10.31492 1.66332   20.52795  1.000 26.55137  ? 123 ALA A CB  1 
ATOM   2179 N  N   . ILE B 1 144 ? -10.22150 -0.65996  18.40333  1.000 29.57204  ? 124 ILE A N   1 
ATOM   2180 C  CA  . ILE B 1 144 ? -9.49190  -1.68800  17.66334  1.000 36.96777  ? 124 ILE A CA  1 
ATOM   2181 C  C   . ILE B 1 144 ? -9.64557  -1.47292  16.16115  1.000 43.31383  ? 124 ILE A C   1 
ATOM   2182 O  O   . ILE B 1 144 ? -8.67011  -1.53644  15.40075  1.000 32.37733  ? 124 ILE A O   1 
ATOM   2183 C  CB  . ILE B 1 144 ? -9.97149  -3.08848  18.08790  1.000 43.45225  ? 124 ILE A CB  1 
ATOM   2184 C  CG1 . ILE B 1 144 ? -9.59826  -3.36251  19.54747  1.000 36.13744  ? 124 ILE A CG1 1 
ATOM   2185 C  CG2 . ILE B 1 144 ? -9.39606  -4.16261  17.16773  1.000 26.46013  ? 124 ILE A CG2 1 
ATOM   2186 C  CD1 . ILE B 1 144 ? -10.24701 -4.60299  20.11929  1.000 32.50471  ? 124 ILE A CD1 1 
ATOM   2187 N  N   . GLU B 1 145 ? -10.87439 -1.20190  15.71250  1.000 34.13331  ? 125 GLU A N   1 
ATOM   2188 C  CA  . GLU B 1 145 ? -11.11439 -1.03638  14.28277  1.000 33.67928  ? 125 GLU A CA  1 
ATOM   2189 C  C   . GLU B 1 145 ? -10.44270 0.22155   13.74597  1.000 41.51681  ? 125 GLU A C   1 
ATOM   2190 O  O   . GLU B 1 145 ? -9.89137  0.20947   12.63901  1.000 43.39665  ? 125 GLU A O   1 
ATOM   2191 C  CB  . GLU B 1 145 ? -12.61710 -1.01259  14.00106  1.000 38.80420  ? 125 GLU A CB  1 
ATOM   2192 C  CG  . GLU B 1 145 ? -13.25663 -2.39145  13.95732  1.000 37.99915  ? 125 GLU A CG  1 
ATOM   2193 C  CD  . GLU B 1 145 ? -12.75415 -3.22598  12.79114  1.000 63.12327  ? 125 GLU A CD  1 
ATOM   2194 O  OE1 . GLU B 1 145 ? -12.68057 -2.69225  11.66227  1.000 61.65621  ? 125 GLU A OE1 1 
ATOM   2195 O  OE2 . GLU B 1 145 ? -12.42532 -4.41200  13.00650  1.000 52.84257  ? 125 GLU A OE2 1 
ATOM   2196 N  N   . THR B 1 146 ? -10.47419 1.31496   14.51443  1.000 42.30560  ? 126 THR A N   1 
ATOM   2197 C  CA  . THR B 1 146 ? -9.83835  2.55173   14.07396  1.000 37.29184  ? 126 THR A CA  1 
ATOM   2198 C  C   . THR B 1 146 ? -8.32436  2.40192   14.02749  1.000 39.52302  ? 126 THR A C   1 
ATOM   2199 O  O   . THR B 1 146 ? -7.66600  2.95344   13.13764  1.000 44.15154  ? 126 THR A O   1 
ATOM   2200 C  CB  . THR B 1 146 ? -10.23583 3.70238   14.99931  1.000 31.85458  ? 126 THR A CB  1 
ATOM   2201 O  OG1 . THR B 1 146 ? -11.66356 3.75523   15.10848  1.000 32.29861  ? 126 THR A OG1 1 
ATOM   2202 C  CG2 . THR B 1 146 ? -9.72425  5.02863   14.45937  1.000 24.48622  ? 126 THR A CG2 1 
ATOM   2203 N  N   . ALA B 1 147 ? -7.75215  1.65831   14.97661  1.000 35.68955  ? 127 ALA A N   1 
ATOM   2204 C  CA  . ALA B 1 147 ? -6.31383  1.42615   14.94889  1.000 40.86772  ? 127 ALA A CA  1 
ATOM   2205 C  C   . ALA B 1 147 ? -5.92506  0.52906   13.78050  1.000 40.51361  ? 127 ALA A C   1 
ATOM   2206 O  O   . ALA B 1 147 ? -4.88679  0.74626   13.14655  1.000 41.37179  ? 127 ALA A O   1 
ATOM   2207 C  CB  . ALA B 1 147 ? -5.85198  0.82326   16.27518  1.000 32.22682  ? 127 ALA A CB  1 
ATOM   2208 N  N   . ALA B 1 148 ? -6.74599  -0.47846  13.47215  1.000 41.29972  ? 128 ALA A N   1 
ATOM   2209 C  CA  . ALA B 1 148 ? -6.42761  -1.36150  12.35345  1.000 46.46996  ? 128 ALA A CA  1 
ATOM   2210 C  C   . ALA B 1 148 ? -6.55037  -0.63062  11.02092  1.000 48.43475  ? 128 ALA A C   1 
ATOM   2211 O  O   . ALA B 1 148 ? -5.67036  -0.73977  10.15808  1.000 42.42668  ? 128 ALA A O   1 
ATOM   2212 C  CB  . ALA B 1 148 ? -7.33122  -2.59361  12.37816  1.000 33.11857  ? 128 ALA A CB  1 
ATOM   2213 N  N   . GLN B 1 149 ? -7.63939  0.12154   10.83652  1.000 43.42642  ? 129 GLN A N   1 
ATOM   2214 C  CA  . GLN B 1 149 ? -7.85930  0.85241   9.59390   1.000 39.13028  ? 129 GLN A CA  1 
ATOM   2215 C  C   . GLN B 1 149 ? -6.84375  1.96835   9.38440   1.000 47.36485  ? 129 GLN A C   1 
ATOM   2216 O  O   . GLN B 1 149 ? -6.65003  2.40835   8.24521   1.000 49.32350  ? 129 GLN A O   1 
ATOM   2217 C  CB  . GLN B 1 149 ? -9.27704  1.42052   9.57475   1.000 45.54340  ? 129 GLN A CB  1 
ATOM   2218 C  CG  . GLN B 1 149 ? -10.34750 0.35087   9.44481   1.000 55.62182  ? 129 GLN A CG  1 
ATOM   2219 C  CD  . GLN B 1 149 ? -11.69127 0.79183   9.98656   1.000 72.14079  ? 129 GLN A CD  1 
ATOM   2220 O  OE1 . GLN B 1 149 ? -11.96519 1.98655   10.11823  1.000 66.63154  ? 129 GLN A OE1 1 
ATOM   2221 N  NE2 . GLN B 1 149 ? -12.53891 -0.17727  10.31122  1.000 68.87966  ? 129 GLN A NE2 1 
ATOM   2222 N  N   . ALA B 1 150 ? -6.19785  2.43904   10.45036  1.000 48.78343  ? 130 ALA A N   1 
ATOM   2223 C  CA  . ALA B 1 150 ? -5.10518  3.39556   10.33765  1.000 42.75633  ? 130 ALA A CA  1 
ATOM   2224 C  C   . ALA B 1 150 ? -3.77749  2.72481   10.02017  1.000 40.62636  ? 130 ALA A C   1 
ATOM   2225 O  O   . ALA B 1 150 ? -2.73313  3.38069   10.09412  1.000 41.55118  ? 130 ALA A O   1 
ATOM   2226 C  CB  . ALA B 1 150 ? -4.98281  4.21060   11.62814  1.000 33.16217  ? 130 ALA A CB  1 
ATOM   2227 N  N   . GLY B 1 151 ? -3.79628  1.44214   9.66172   1.000 46.48709  ? 131 GLY A N   1 
ATOM   2228 C  CA  . GLY B 1 151 ? -2.56797  0.72015   9.39965   1.000 44.75221  ? 131 GLY A CA  1 
ATOM   2229 C  C   . GLY B 1 151 ? -1.79848  0.34700   10.64148  1.000 51.24264  ? 131 GLY A C   1 
ATOM   2230 O  O   . GLY B 1 151 ? -0.57906  0.16523   10.57623  1.000 55.73374  ? 131 GLY A O   1 
ATOM   2231 N  N   . GLY B 1 152 ? -2.48301  0.21387   11.77519  1.000 51.47835  ? 132 GLY A N   1 
ATOM   2232 C  CA  . GLY B 1 152 ? -1.79764  0.01969   13.03656  1.000 38.39607  ? 132 GLY A CA  1 
ATOM   2233 C  C   . GLY B 1 152 ? -1.30273  -1.40604  13.21123  1.000 37.81686  ? 132 GLY A C   1 
ATOM   2234 O  O   . GLY B 1 152 ? -1.95757  -2.37215  12.82501  1.000 46.04660  ? 132 GLY A O   1 
ATOM   2235 N  N   . ASP B 1 153 ? -0.12204  -1.52312  13.80882  1.000 43.23529  ? 133 ASP A N   1 
ATOM   2236 C  CA  . ASP B 1 153 ? 0.45778   -2.82741  14.09303  1.000 51.85241  ? 133 ASP A CA  1 
ATOM   2237 C  C   . ASP B 1 153 ? -0.05386  -3.38830  15.41277  1.000 51.81269  ? 133 ASP A C   1 
ATOM   2238 O  O   . ASP B 1 153 ? -0.21789  -4.60850  15.54348  1.000 42.76477  ? 133 ASP A O   1 
ATOM   2239 C  CB  . ASP B 1 153 ? 1.98689   -2.71448  14.10730  1.000 53.10508  ? 133 ASP A CB  1 
ATOM   2240 C  CG  . ASP B 1 153 ? 2.68117   -4.05997  14.08114  1.000 62.01053  ? 133 ASP A CG  1 
ATOM   2241 O  OD1 . ASP B 1 153 ? 1.99352   -5.10234  14.04197  1.000 76.17219  ? 133 ASP A OD1 1 
ATOM   2242 O  OD2 . ASP B 1 153 ? 3.92639   -4.06930  14.09502  1.000 58.58721  ? 133 ASP A OD2 1 
ATOM   2243 N  N   . ALA B 1 154 ? -0.33547  -2.52186  16.38338  1.000 41.44572  ? 134 ALA A N   1 
ATOM   2244 C  CA  . ALA B 1 154 ? -0.76410  -2.97862  17.69597  1.000 39.42676  ? 134 ALA A CA  1 
ATOM   2245 C  C   . ALA B 1 154 ? -1.51386  -1.85637  18.39467  1.000 37.73078  ? 134 ALA A C   1 
ATOM   2246 O  O   . ALA B 1 154 ? -1.42072  -0.68729  18.01353  1.000 33.11702  ? 134 ALA A O   1 
ATOM   2247 C  CB  . ALA B 1 154 ? 0.42401   -3.44157  18.54595  1.000 32.89422  ? 134 ALA A CB  1 
ATOM   2248 N  N   . LEU B 1 155 ? -2.25958  -2.23356  19.42789  1.000 31.79080  ? 135 LEU A N   1 
ATOM   2249 C  CA  . LEU B 1 155 ? -2.96766  -1.29178  20.28636  1.000 30.75492  ? 135 LEU A CA  1 
ATOM   2250 C  C   . LEU B 1 155 ? -2.45767  -1.49216  21.70652  1.000 33.71358  ? 135 LEU A C   1 
ATOM   2251 O  O   . LEU B 1 155 ? -2.71554  -2.53135  22.32325  1.000 33.03389  ? 135 LEU A O   1 
ATOM   2252 C  CB  . LEU B 1 155 ? -4.47885  -1.49377  20.19935  1.000 30.48629  ? 135 LEU A CB  1 
ATOM   2253 C  CG  . LEU B 1 155 ? -5.35238  -0.47852  20.93586  1.000 37.31980  ? 135 LEU A CG  1 
ATOM   2254 C  CD1 . LEU B 1 155 ? -4.99740  0.95766   20.54919  1.000 26.25957  ? 135 LEU A CD1 1 
ATOM   2255 C  CD2 . LEU B 1 155 ? -6.81943  -0.76141  20.65935  1.000 30.60421  ? 135 LEU A CD2 1 
ATOM   2256 N  N   . ARG B 1 156 ? -1.71144  -0.51412  22.20921  1.000 36.03061  ? 136 ARG A N   1 
ATOM   2257 C  CA  . ARG B 1 156 ? -1.16016  -0.54802  23.55397  1.000 34.29468  ? 136 ARG A CA  1 
ATOM   2258 C  C   . ARG B 1 156 ? -1.95061  0.38904   24.45661  1.000 34.19458  ? 136 ARG A C   1 
ATOM   2259 O  O   . ARG B 1 156 ? -2.46745  1.41793   24.00923  1.000 34.34438  ? 136 ARG A O   1 
ATOM   2260 C  CB  . ARG B 1 156 ? 0.31914   -0.15489  23.54489  1.000 35.46423  ? 136 ARG A CB  1 
ATOM   2261 C  CG  . ARG B 1 156 ? 1.19606   -1.13872  22.79702  1.000 36.03624  ? 136 ARG A CG  1 
ATOM   2262 C  CD  . ARG B 1 156 ? 2.58522   -0.58246  22.55210  1.000 38.78798  ? 136 ARG A CD  1 
ATOM   2263 N  NE  . ARG B 1 156 ? 3.45870   -1.58063  21.94787  1.000 41.15562  ? 136 ARG A NE  1 
ATOM   2264 C  CZ  . ARG B 1 156 ? 4.71865   -1.36416  21.59642  1.000 45.26825  ? 136 ARG A CZ  1 
ATOM   2265 N  NH1 . ARG B 1 156 ? 5.29078   -0.18311  21.76452  1.000 42.32179  ? 136 ARG A NH1 1 
ATOM   2266 N  NH2 . ARG B 1 156 ? 5.42342   -2.35904  21.06525  1.000 44.92725  ? 136 ARG A NH2 1 
ATOM   2267 N  N   . SER B 1 157 ? -2.04265  0.02733   25.73475  1.000 32.64556  ? 137 SER A N   1 
ATOM   2268 C  CA  . SER B 1 157 ? -2.87466  0.79673   26.64882  1.000 31.65662  ? 137 SER A CA  1 
ATOM   2269 C  C   . SER B 1 157 ? -2.34869  0.66633   28.06947  1.000 31.76461  ? 137 SER A C   1 
ATOM   2270 O  O   . SER B 1 157 ? -1.65057  -0.29067  28.40966  1.000 43.14197  ? 137 SER A O   1 
ATOM   2271 C  CB  . SER B 1 157 ? -4.33938  0.34487   26.58311  1.000 23.37946  ? 137 SER A CB  1 
ATOM   2272 O  OG  . SER B 1 157 ? -5.18010  1.22651   27.30961  1.000 36.45340  ? 137 SER A OG  1 
ATOM   2273 N  N   . GLU B 1 158 ? -2.70028  1.64650   28.89678  1.000 31.44684  ? 138 GLU A N   1 
ATOM   2274 C  CA  . GLU B 1 158 ? -2.44019  1.61722   30.32862  1.000 34.80847  ? 138 GLU A CA  1 
ATOM   2275 C  C   . GLU B 1 158 ? -3.76861  1.46178   31.05236  1.000 31.90989  ? 138 GLU A C   1 
ATOM   2276 O  O   . GLU B 1 158 ? -4.69680  2.24234   30.82017  1.000 41.39942  ? 138 GLU A O   1 
ATOM   2277 C  CB  . GLU B 1 158 ? -1.72708  2.89096   30.78023  1.000 32.38327  ? 138 GLU A CB  1 
ATOM   2278 C  CG  . GLU B 1 158 ? -1.27776  2.88654   32.22841  1.000 31.48263  ? 138 GLU A CG  1 
ATOM   2279 C  CD  . GLU B 1 158 ? -0.53251  4.15202   32.58633  1.000 43.66222  ? 138 GLU A CD  1 
ATOM   2280 O  OE1 . GLU B 1 158 ? -1.16668  5.22764   32.61480  1.000 38.75176  ? 138 GLU A OE1 1 
ATOM   2281 O  OE2 . GLU B 1 158 ? 0.69289   4.07421   32.81218  1.000 46.77074  ? 138 GLU A OE2 1 
ATOM   2282 N  N   . ALA B 1 159 ? -3.86499  0.45281   31.91473  1.000 26.38601  ? 139 ALA A N   1 
ATOM   2283 C  CA  . ALA B 1 159 ? -5.12672  0.12269   32.55908  1.000 27.67132  ? 139 ALA A CA  1 
ATOM   2284 C  C   . ALA B 1 159 ? -4.96745  0.10457   34.07176  1.000 29.58039  ? 139 ALA A C   1 
ATOM   2285 O  O   . ALA B 1 159 ? -3.86818  -0.06382  34.60618  1.000 25.86944  ? 139 ALA A O   1 
ATOM   2286 C  CB  . ALA B 1 159 ? -5.66712  -1.23346  32.08017  1.000 24.55145  ? 139 ALA A CB  1 
ATOM   2287 N  N   . ASN B 1 160 ? -6.09748  0.27723   34.75587  1.000 36.60422  ? 140 ASN A N   1 
ATOM   2288 C  CA  . ASN B 1 160 ? -6.15493  0.15220   36.20258  1.000 36.69601  ? 140 ASN A CA  1 
ATOM   2289 C  C   . ASN B 1 160 ? -6.65549  -1.24235  36.54200  1.000 32.63768  ? 140 ASN A C   1 
ATOM   2290 O  O   . ASN B 1 160 ? -7.83361  -1.54167  36.29404  1.000 35.99393  ? 140 ASN A O   1 
ATOM   2291 C  CB  . ASN B 1 160 ? -7.07779  1.21396   36.79841  1.000 31.13350  ? 140 ASN A CB  1 
ATOM   2292 C  CG  . ASN B 1 160 ? -6.99732  1.28181   38.31474  1.000 35.34657  ? 140 ASN A CG  1 
ATOM   2293 O  OD1 . ASN B 1 160 ? -6.80304  0.26864   38.98734  1.000 44.03336  ? 140 ASN A OD1 1 
ATOM   2294 N  ND2 . ASN B 1 160 ? -7.14322  2.48268   38.85921  1.000 35.68403  ? 140 ASN A ND2 1 
ATOM   2295 N  N   . PRO B 1 161 ? -5.82019  -2.12559  37.09449  1.000 38.35309  ? 141 PRO A N   1 
ATOM   2296 C  CA  . PRO B 1 161 ? -6.29694  -3.48268  37.40498  1.000 42.56996  ? 141 PRO A CA  1 
ATOM   2297 C  C   . PRO B 1 161 ? -7.37637  -3.51579  38.46875  1.000 33.71834  ? 141 PRO A C   1 
ATOM   2298 O  O   . PRO B 1 161 ? -8.12853  -4.49583  38.53490  1.000 37.80543  ? 141 PRO A O   1 
ATOM   2299 C  CB  . PRO B 1 161 ? -5.02588  -4.20260  37.87626  1.000 33.78997  ? 141 PRO A CB  1 
ATOM   2300 C  CG  . PRO B 1 161 ? -4.14829  -3.11156  38.38754  1.000 31.52721  ? 141 PRO A CG  1 
ATOM   2301 C  CD  . PRO B 1 161 ? -4.41324  -1.93449  37.48641  1.000 41.53834  ? 141 PRO A CD  1 
ATOM   2302 N  N   . ASP B 1 162 ? -7.48469  -2.47788  39.29889  1.000 33.59253  ? 142 ASP A N   1 
ATOM   2303 C  CA  . ASP B 1 162 ? -8.52046  -2.42572  40.32297  1.000 45.07509  ? 142 ASP A CA  1 
ATOM   2304 C  C   . ASP B 1 162 ? -9.89905  -2.10799  39.76073  1.000 39.41535  ? 142 ASP A C   1 
ATOM   2305 O  O   . ASP B 1 162 ? -10.89302 -2.29151  40.47061  1.000 40.59917  ? 142 ASP A O   1 
ATOM   2306 C  CB  . ASP B 1 162 ? -8.14690  -1.39935  41.39380  1.000 38.82145  ? 142 ASP A CB  1 
ATOM   2307 C  CG  . ASP B 1 162 ? -6.93434  -1.81885  42.19139  1.000 39.33553  ? 142 ASP A CG  1 
ATOM   2308 O  OD1 . ASP B 1 162 ? -6.58582  -3.01486  42.13857  1.000 46.60049  ? 142 ASP A OD1 1 
ATOM   2309 O  OD2 . ASP B 1 162 ? -6.32189  -0.95703  42.85668  1.000 52.86305  ? 142 ASP A OD2 1 
ATOM   2310 N  N   . LEU B 1 163 ? -9.98552  -1.63694  38.51683  1.000 37.99811  ? 143 LEU A N   1 
ATOM   2311 C  CA  . LEU B 1 163 ? -11.26398 -1.51859  37.81500  1.000 38.22557  ? 143 LEU A CA  1 
ATOM   2312 C  C   . LEU B 1 163 ? -11.53554 -2.87573  37.17892  1.000 34.23492  ? 143 LEU A C   1 
ATOM   2313 O  O   . LEU B 1 163 ? -11.17890 -3.13121  36.02842  1.000 41.51636  ? 143 LEU A O   1 
ATOM   2314 C  CB  . LEU B 1 163 ? -11.22269 -0.39448  36.78692  1.000 29.47667  ? 143 LEU A CB  1 
ATOM   2315 C  CG  . LEU B 1 163 ? -10.89009 1.00388   37.32072  1.000 38.75073  ? 143 LEU A CG  1 
ATOM   2316 C  CD1 . LEU B 1 163 ? -10.99588 2.05299   36.22107  1.000 34.38695  ? 143 LEU A CD1 1 
ATOM   2317 C  CD2 . LEU B 1 163 ? -11.77851 1.37101   38.50363  1.000 45.55080  ? 143 LEU A CD2 1 
ATOM   2318 N  N   . SER B 1 164 ? -12.18181 -3.75699  37.94766  1.000 38.31854  ? 144 SER A N   1 
ATOM   2319 C  CA  . SER B 1 164 ? -12.23336 -5.17402  37.59273  1.000 40.12882  ? 144 SER A CA  1 
ATOM   2320 C  C   . SER B 1 164 ? -12.98871 -5.41511  36.28900  1.000 40.09192  ? 144 SER A C   1 
ATOM   2321 O  O   . SER B 1 164 ? -12.55214 -6.21650  35.45414  1.000 37.36223  ? 144 SER A O   1 
ATOM   2322 C  CB  . SER B 1 164 ? -12.86529 -5.96813  38.73480  1.000 39.26789  ? 144 SER A CB  1 
ATOM   2323 O  OG  . SER B 1 164 ? -14.12405 -5.42431  39.09029  1.000 54.98439  ? 144 SER A OG  1 
ATOM   2324 N  N   . ALA B 1 165 ? -14.12423 -4.73955  36.09575  1.000 40.32735  ? 145 ALA A N   1 
ATOM   2325 C  CA  . ALA B 1 165 ? -14.91287 -4.95109  34.88419  1.000 36.89703  ? 145 ALA A CA  1 
ATOM   2326 C  C   . ALA B 1 165 ? -14.12158 -4.57341  33.63674  1.000 36.89021  ? 145 ALA A C   1 
ATOM   2327 O  O   . ALA B 1 165 ? -14.05158 -5.34584  32.67208  1.000 41.02899  ? 145 ALA A O   1 
ATOM   2328 C  CB  . ALA B 1 165 ? -16.21367 -4.15276  34.96042  1.000 36.80646  ? 145 ALA A CB  1 
ATOM   2329 N  N   . THR B 1 166 ? -13.50550 -3.38809  33.64599  1.000 34.24745  ? 146 THR A N   1 
ATOM   2330 C  CA  . THR B 1 166 ? -12.74677 -2.92857  32.48583  1.000 32.33165  ? 146 THR A CA  1 
ATOM   2331 C  C   . THR B 1 166 ? -11.51165 -3.79153  32.24924  1.000 35.02913  ? 146 THR A C   1 
ATOM   2332 O  O   . THR B 1 166 ? -11.17993 -4.10612  31.10048  1.000 31.37269  ? 146 THR A O   1 
ATOM   2333 C  CB  . THR B 1 166 ? -12.35033 -1.46229  32.66783  1.000 38.37179  ? 146 THR A CB  1 
ATOM   2334 O  OG1 . THR B 1 166 ? -13.51804 -0.68154  32.95304  1.000 51.12899  ? 146 THR A OG1 1 
ATOM   2335 C  CG2 . THR B 1 166 ? -11.68337 -0.92201  31.40736  1.000 43.28143  ? 146 THR A CG2 1 
ATOM   2336 N  N   . ARG B 1 167 ? -10.81818 -4.18300  33.32163  1.000 33.55074  ? 147 ARG A N   1 
ATOM   2337 C  CA  . ARG B 1 167 ? -9.64811  -5.04355  33.17198  1.000 38.21176  ? 147 ARG A CA  1 
ATOM   2338 C  C   . ARG B 1 167 ? -10.02860 -6.38500  32.55870  1.000 39.06161  ? 147 ARG A C   1 
ATOM   2339 O  O   . ARG B 1 167 ? -9.34841  -6.87932  31.64894  1.000 28.06834  ? 147 ARG A O   1 
ATOM   2340 C  CB  . ARG B 1 167 ? -8.96922  -5.24643  34.52706  1.000 30.50837  ? 147 ARG A CB  1 
ATOM   2341 C  CG  . ARG B 1 167 ? -7.69870  -6.08173  34.46817  1.000 31.44702  ? 147 ARG A CG  1 
ATOM   2342 C  CD  . ARG B 1 167 ? -6.62780  -5.39356  33.63564  1.000 29.67933  ? 147 ARG A CD  1 
ATOM   2343 N  NE  . ARG B 1 167 ? -5.44839  -6.23334  33.47423  1.000 26.07033  ? 147 ARG A NE  1 
ATOM   2344 C  CZ  . ARG B 1 167 ? -5.26645  -7.08220  32.47209  1.000 32.95881  ? 147 ARG A CZ  1 
ATOM   2345 N  NH1 . ARG B 1 167 ? -6.16757  -7.22396  31.51364  1.000 28.67312  ? 147 ARG A NH1 1 
ATOM   2346 N  NH2 . ARG B 1 167 ? -4.15258  -7.80800  32.43063  1.000 32.62897  ? 147 ARG A NH2 1 
ATOM   2347 N  N   . SER B 1 168 ? -11.12557 -6.98065  33.03458  1.000 39.67009  ? 148 SER A N   1 
ATOM   2348 C  CA  . SER B 1 168 ? -11.57569 -8.25398  32.48498  1.000 33.19989  ? 148 SER A CA  1 
ATOM   2349 C  C   . SER B 1 168 ? -11.99547 -8.10775  31.02808  1.000 34.36594  ? 148 SER A C   1 
ATOM   2350 O  O   . SER B 1 168 ? -11.69555 -8.97603  30.20168  1.000 29.77894  ? 148 SER A O   1 
ATOM   2351 C  CB  . SER B 1 168 ? -12.72461 -8.80888  33.32670  1.000 32.66714  ? 148 SER A CB  1 
ATOM   2352 O  OG  . SER B 1 168 ? -13.18177 -10.04824 32.81501  1.000 52.35490  ? 148 SER A OG  1 
ATOM   2353 N  N   . LEU B 1 169 ? -12.68552 -7.01217  30.69291  1.000 35.17727  ? 149 LEU A N   1 
ATOM   2354 C  CA  . LEU B 1 169 ? -13.08780 -6.78431  29.30758  1.000 31.80815  ? 149 LEU A CA  1 
ATOM   2355 C  C   . LEU B 1 169 ? -11.87536 -6.62807  28.39723  1.000 38.52426  ? 149 LEU A C   1 
ATOM   2356 O  O   . LEU B 1 169 ? -11.85195 -7.16652  27.28320  1.000 37.54378  ? 149 LEU A O   1 
ATOM   2357 C  CB  . LEU B 1 169 ? -13.98989 -5.55178  29.21873  1.000 30.40442  ? 149 LEU A CB  1 
ATOM   2358 C  CG  . LEU B 1 169 ? -14.36699 -5.08759  27.80872  1.000 31.32080  ? 149 LEU A CG  1 
ATOM   2359 C  CD1 . LEU B 1 169 ? -15.06731 -6.19845  27.04216  1.000 31.71912  ? 149 LEU A CD1 1 
ATOM   2360 C  CD2 . LEU B 1 169 ? -15.23376 -3.83459  27.85890  1.000 34.94090  ? 149 LEU A CD2 1 
ATOM   2361 N  N   . LEU B 1 170 ? -10.86063 -5.88783  28.85116  1.000 39.55833  ? 150 LEU A N   1 
ATOM   2362 C  CA  . LEU B 1 170 ? -9.63131  -5.76268  28.07521  1.000 35.62078  ? 150 LEU A CA  1 
ATOM   2363 C  C   . LEU B 1 170 ? -8.95642  -7.11681  27.90007  1.000 39.17438  ? 150 LEU A C   1 
ATOM   2364 O  O   . LEU B 1 170 ? -8.42643  -7.42115  26.82475  1.000 36.24903  ? 150 LEU A O   1 
ATOM   2365 C  CB  . LEU B 1 170 ? -8.68293  -4.76984  28.74995  1.000 36.34924  ? 150 LEU A CB  1 
ATOM   2366 C  CG  . LEU B 1 170 ? -9.06784  -3.28829  28.70206  1.000 33.93839  ? 150 LEU A CG  1 
ATOM   2367 C  CD1 . LEU B 1 170 ? -8.41758  -2.52271  29.84167  1.000 26.99548  ? 150 LEU A CD1 1 
ATOM   2368 C  CD2 . LEU B 1 170 ? -8.67855  -2.67640  27.36554  1.000 26.23981  ? 150 LEU A CD2 1 
ATOM   2369 N  N   . ASP B 1 171 ? -8.97389  -7.94849  28.94487  1.000 38.47379  ? 151 ASP A N   1 
ATOM   2370 C  CA  . ASP B 1 171 ? -8.35218  -9.26501  28.84259  1.000 41.98553  ? 151 ASP A CA  1 
ATOM   2371 C  C   . ASP B 1 171 ? -9.09790  -10.15743 27.85688  1.000 40.03288  ? 151 ASP A C   1 
ATOM   2372 O  O   . ASP B 1 171 ? -8.47427  -10.89443 27.08482  1.000 43.32267  ? 151 ASP A O   1 
ATOM   2373 C  CB  . ASP B 1 171 ? -8.28723  -9.92242  30.21966  1.000 36.63265  ? 151 ASP A CB  1 
ATOM   2374 C  CG  . ASP B 1 171 ? -7.68834  -11.31228 30.17205  1.000 35.83006  ? 151 ASP A CG  1 
ATOM   2375 O  OD1 . ASP B 1 171 ? -6.47085  -11.42963 29.91697  1.000 40.79059  ? 151 ASP A OD1 1 
ATOM   2376 O  OD2 . ASP B 1 171 ? -8.43688  -12.28745 30.38957  1.000 46.85936  ? 151 ASP A OD2 1 
ATOM   2377 N  N   . ILE B 1 172 ? -10.43190 -10.10327 27.86851  1.000 39.66638  ? 152 ILE A N   1 
ATOM   2378 C  CA  . ILE B 1 172 ? -11.22806 -10.92642 26.96310  1.000 33.57258  ? 152 ILE A CA  1 
ATOM   2379 C  C   . ILE B 1 172 ? -10.99541 -10.51687 25.51564  1.000 34.78801  ? 152 ILE A C   1 
ATOM   2380 O  O   . ILE B 1 172 ? -11.00608 -11.36153 24.61192  1.000 36.94261  ? 152 ILE A O   1 
ATOM   2381 C  CB  . ILE B 1 172 ? -12.72003 -10.83960 27.34590  1.000 36.60758  ? 152 ILE A CB  1 
ATOM   2382 C  CG1 . ILE B 1 172 ? -12.94890 -11.43096 28.73677  1.000 31.60289  ? 152 ILE A CG1 1 
ATOM   2383 C  CG2 . ILE B 1 172 ? -13.58946 -11.54817 26.31452  1.000 38.03091  ? 152 ILE A CG2 1 
ATOM   2384 C  CD1 . ILE B 1 172 ? -14.34911 -11.22078 29.26345  1.000 39.03457  ? 152 ILE A CD1 1 
ATOM   2385 N  N   . LEU B 1 173 ? -10.77698 -9.22761  25.26726  1.000 36.02909  ? 153 LEU A N   1 
ATOM   2386 C  CA  . LEU B 1 173 ? -10.57529 -8.73957  23.90956  1.000 36.76321  ? 153 LEU A CA  1 
ATOM   2387 C  C   . LEU B 1 173 ? -9.14341  -8.90688  23.41640  1.000 31.88897  ? 153 LEU A C   1 
ATOM   2388 O  O   . LEU B 1 173 ? -8.83066  -8.44288  22.31442  1.000 35.01924  ? 153 LEU A O   1 
ATOM   2389 C  CB  . LEU B 1 173 ? -10.99109 -7.26874  23.81151  1.000 34.02122  ? 153 LEU A CB  1 
ATOM   2390 C  CG  . LEU B 1 173 ? -12.49827 -7.00468  23.87283  1.000 26.96642  ? 153 LEU A CG  1 
ATOM   2391 C  CD1 . LEU B 1 173 ? -12.80551 -5.56681  23.50082  1.000 34.19585  ? 153 LEU A CD1 1 
ATOM   2392 C  CD2 . LEU B 1 173 ? -13.25518 -7.96416  22.96554  1.000 35.10720  ? 153 LEU A CD2 1 
ATOM   2393 N  N   . GLY B 1 174 ? -8.27384  -9.54941  24.18967  1.000 32.42158  ? 154 GLY A N   1 
ATOM   2394 C  CA  . GLY B 1 174 ? -6.93156  -9.85046  23.74137  1.000 30.17071  ? 154 GLY A CA  1 
ATOM   2395 C  C   . GLY B 1 174 ? -5.84276  -8.89714  24.17857  1.000 32.47121  ? 154 GLY A C   1 
ATOM   2396 O  O   . GLY B 1 174 ? -4.73830  -8.96031  23.62639  1.000 37.63877  ? 154 GLY A O   1 
ATOM   2397 N  N   . PHE B 1 175 ? -6.10802  -8.01924  25.14240  1.000 35.18249  ? 155 PHE A N   1 
ATOM   2398 C  CA  . PHE B 1 175 ? -5.07355  -7.12862  25.65847  1.000 38.08116  ? 155 PHE A CA  1 
ATOM   2399 C  C   . PHE B 1 175 ? -4.25003  -7.89552  26.68587  1.000 36.37907  ? 155 PHE A C   1 
ATOM   2400 O  O   . PHE B 1 175 ? -4.72030  -8.16436  27.79469  1.000 38.17470  ? 155 PHE A O   1 
ATOM   2401 C  CB  . PHE B 1 175 ? -5.69128  -5.87025  26.26118  1.000 32.54663  ? 155 PHE A CB  1 
ATOM   2402 C  CG  . PHE B 1 175 ? -6.21203  -4.89871  25.23629  1.000 31.95541  ? 155 PHE A CG  1 
ATOM   2403 C  CD1 . PHE B 1 175 ? -7.46817  -5.06413  24.67905  1.000 28.46007  ? 155 PHE A CD1 1 
ATOM   2404 C  CD2 . PHE B 1 175 ? -5.44278  -3.81865  24.83299  1.000 36.01849  ? 155 PHE A CD2 1 
ATOM   2405 C  CE1 . PHE B 1 175 ? -7.94761  -4.17319  23.73685  1.000 32.66777  ? 155 PHE A CE1 1 
ATOM   2406 C  CE2 . PHE B 1 175 ? -5.91731  -2.92383  23.89127  1.000 34.04575  ? 155 PHE A CE2 1 
ATOM   2407 C  CZ  . PHE B 1 175 ? -7.17118  -3.10100  23.34218  1.000 31.77929  ? 155 PHE A CZ  1 
ATOM   2408 N  N   . VAL B 1 176 ? -3.02472  -8.25525  26.31795  1.000 33.59229  ? 156 VAL A N   1 
ATOM   2409 C  CA  . VAL B 1 176 ? -2.15903  -9.07317  27.16205  1.000 31.86459  ? 156 VAL A CA  1 
ATOM   2410 C  C   . VAL B 1 176 ? -1.27890  -8.15286  27.99784  1.000 34.63686  ? 156 VAL A C   1 
ATOM   2411 O  O   . VAL B 1 176 ? -0.72834  -7.17107  27.48536  1.000 31.79700  ? 156 VAL A O   1 
ATOM   2412 C  CB  . VAL B 1 176 ? -1.30702  -10.02963 26.30951  1.000 38.85703  ? 156 VAL A CB  1 
ATOM   2413 C  CG1 . VAL B 1 176 ? -0.37512  -10.84686 27.19207  1.000 26.91485  ? 156 VAL A CG1 1 
ATOM   2414 C  CG2 . VAL B 1 176 ? -2.21096  -10.93658 25.47319  1.000 23.49464  ? 156 VAL A CG2 1 
ATOM   2415 N  N   . GLN B 1 177 ? -1.15684  -8.45342  29.28883  1.000 28.28536  ? 157 GLN A N   1 
ATOM   2416 C  CA  . GLN B 1 177 ? -0.32380  -7.64343  30.16739  1.000 35.10347  ? 157 GLN A CA  1 
ATOM   2417 C  C   . GLN B 1 177 ? 1.14343   -8.00437  29.98246  1.000 41.82202  ? 157 GLN A C   1 
ATOM   2418 O  O   . GLN B 1 177 ? 1.49960   -9.18582  29.92603  1.000 38.17607  ? 157 GLN A O   1 
ATOM   2419 C  CB  . GLN B 1 177 ? -0.73148  -7.83026  31.62842  1.000 31.14547  ? 157 GLN A CB  1 
ATOM   2420 C  CG  . GLN B 1 177 ? 0.19308   -7.12873  32.62130  1.000 26.14171  ? 157 GLN A CG  1 
ATOM   2421 C  CD  . GLN B 1 177 ? -0.36741  -7.10403  34.03031  1.000 36.37600  ? 157 GLN A CD  1 
ATOM   2422 O  OE1 . GLN B 1 177 ? -1.57921  -7.17133  34.22540  1.000 35.13315  ? 157 GLN A OE1 1 
ATOM   2423 N  NE2 . GLN B 1 177 ? 0.51466   -7.00600  35.02167  1.000 36.22148  ? 157 GLN A NE2 1 
ATOM   2424 N  N   . HIS B 1 178 ? 1.99351   -6.98417  29.87570  1.000 39.74001  ? 158 HIS A N   1 
ATOM   2425 C  CA  . HIS B 1 178 ? 3.43596   -7.18334  29.85648  1.000 40.66183  ? 158 HIS A CA  1 
ATOM   2426 C  C   . HIS B 1 178 ? 4.07737   -6.32519  30.93624  1.000 41.52913  ? 158 HIS A C   1 
ATOM   2427 O  O   . HIS B 1 178 ? 3.69186   -5.16939  31.13545  1.000 40.53054  ? 158 HIS A O   1 
ATOM   2428 C  CB  . HIS B 1 178 ? 4.03363   -6.85832  28.48287  1.000 44.17256  ? 158 HIS A CB  1 
ATOM   2429 C  CG  . HIS B 1 178 ? 3.64963   -7.83772  27.41825  1.000 45.59265  ? 158 HIS A CG  1 
ATOM   2430 N  ND1 . HIS B 1 178 ? 2.48818   -7.72242  26.68541  1.000 52.53011  ? 158 HIS A ND1 1 
ATOM   2431 C  CD2 . HIS B 1 178 ? 4.26159   -8.96287  26.97849  1.000 43.77390  ? 158 HIS A CD2 1 
ATOM   2432 C  CE1 . HIS B 1 178 ? 2.40577   -8.72879  25.83342  1.000 47.81111  ? 158 HIS A CE1 1 
ATOM   2433 N  NE2 . HIS B 1 178 ? 3.47029   -9.49505  25.98958  1.000 42.55211  ? 158 HIS A NE2 1 
ATOM   2434 N  N   . GLY B 1 179 ? 5.05203   -6.90026  31.63543  1.000 34.46493  ? 159 GLY A N   1 
ATOM   2435 C  CA  . GLY B 1 179 ? 5.67219   -6.24335  32.75896  1.000 35.63552  ? 159 GLY A CA  1 
ATOM   2436 C  C   . GLY B 1 179 ? 4.85487   -6.41453  34.02291  1.000 36.82997  ? 159 GLY A C   1 
ATOM   2437 O  O   . GLY B 1 179 ? 3.70591   -6.86475  33.98992  1.000 35.55093  ? 159 GLY A O   1 
ATOM   2438 N  N   . PRO B 1 180 ? 5.43341   -6.06341  35.16543  1.000 38.57032  ? 160 PRO A N   1 
ATOM   2439 C  CA  . PRO B 1 180 ? 4.73238   -6.23871  36.44003  1.000 38.47472  ? 160 PRO A CA  1 
ATOM   2440 C  C   . PRO B 1 180 ? 3.67301   -5.16484  36.65319  1.000 37.15693  ? 160 PRO A C   1 
ATOM   2441 O  O   . PRO B 1 180 ? 3.59994   -4.16124  35.94231  1.000 36.22932  ? 160 PRO A O   1 
ATOM   2442 C  CB  . PRO B 1 180 ? 5.85472   -6.11821  37.47586  1.000 41.35289  ? 160 PRO A CB  1 
ATOM   2443 C  CG  . PRO B 1 180 ? 6.84702   -5.21643  36.82598  1.000 43.70964  ? 160 PRO A CG  1 
ATOM   2444 C  CD  . PRO B 1 180 ? 6.79704   -5.53598  35.35140  1.000 42.58341  ? 160 PRO A CD  1 
ATOM   2445 N  N   . THR B 1 181 ? 2.83917   -5.40367  37.66049  1.000 36.27516  ? 161 THR A N   1 
ATOM   2446 C  CA  . THR B 1 181 ? 1.88574   -4.40132  38.10682  1.000 34.88936  ? 161 THR A CA  1 
ATOM   2447 C  C   . THR B 1 181 ? 2.62425   -3.34028  38.91063  1.000 32.49499  ? 161 THR A C   1 
ATOM   2448 O  O   . THR B 1 181 ? 3.35914   -3.66009  39.85022  1.000 35.02860  ? 161 THR A O   1 
ATOM   2449 C  CB  . THR B 1 181 ? 0.78608   -5.04372  38.94982  1.000 34.70104  ? 161 THR A CB  1 
ATOM   2450 O  OG1 . THR B 1 181 ? 0.09312   -6.02107  38.16126  1.000 38.20173  ? 161 THR A OG1 1 
ATOM   2451 C  CG2 . THR B 1 181 ? -0.20183  -3.99373  39.42181  1.000 34.88177  ? 161 THR A CG2 1 
ATOM   2452 N  N   . LEU B 1 182 ? 2.43613   -2.07992  38.53846  1.000 34.35462  ? 162 LEU A N   1 
ATOM   2453 C  CA  . LEU B 1 182 ? 3.14569   -0.97040  39.15539  1.000 34.62425  ? 162 LEU A CA  1 
ATOM   2454 C  C   . LEU B 1 182 ? 2.22088   -0.20135  40.08774  1.000 32.56213  ? 162 LEU A C   1 
ATOM   2455 O  O   . LEU B 1 182 ? 1.03468   -0.02090  39.79503  1.000 31.61812  ? 162 LEU A O   1 
ATOM   2456 C  CB  . LEU B 1 182 ? 3.71794   -0.02363  38.09657  1.000 33.46033  ? 162 LEU A CB  1 
ATOM   2457 C  CG  . LEU B 1 182 ? 4.77537   -0.59588  37.14969  1.000 37.87570  ? 162 LEU A CG  1 
ATOM   2458 C  CD1 . LEU B 1 182 ? 5.26971   0.47246   36.18414  1.000 33.49868  ? 162 LEU A CD1 1 
ATOM   2459 C  CD2 . LEU B 1 182 ? 5.93069   -1.17927  37.93896  1.000 27.73824  ? 162 LEU A CD2 1 
ATOM   2460 N  N   . SER B 1 183 ? 2.77506   0.23924   41.21371  1.000 37.80222  ? 163 SER A N   1 
ATOM   2461 C  CA  . SER B 1 183 ? 2.11860   1.16240   42.12636  1.000 38.04074  ? 163 SER A CA  1 
ATOM   2462 C  C   . SER B 1 183 ? 2.81263   2.51527   42.04086  1.000 36.38474  ? 163 SER A C   1 
ATOM   2463 O  O   . SER B 1 183 ? 4.03482   2.58416   41.88114  1.000 43.03233  ? 163 SER A O   1 
ATOM   2464 C  CB  . SER B 1 183 ? 2.15445   0.63837   43.56589  1.000 41.47055  ? 163 SER A CB  1 
ATOM   2465 O  OG  . SER B 1 183 ? 1.57161   1.56324   44.47007  1.000 50.52238  ? 163 SER A OG  1 
ATOM   2466 N  N   . ASP B 1 184 ? 2.03265   3.59045   42.14070  1.000 35.73850  ? 164 ASP A N   1 
ATOM   2467 C  CA  . ASP B 1 184 ? 2.55710   4.94266   41.98788  1.000 40.10823  ? 164 ASP A CA  1 
ATOM   2468 C  C   . ASP B 1 184 ? 3.12341   5.51202   43.28337  1.000 35.47636  ? 164 ASP A C   1 
ATOM   2469 O  O   . ASP B 1 184 ? 3.52234   6.68010   43.30804  1.000 39.64930  ? 164 ASP A O   1 
ATOM   2470 C  CB  . ASP B 1 184 ? 1.47598   5.87943   41.43592  1.000 30.41653  ? 164 ASP A CB  1 
ATOM   2471 C  CG  . ASP B 1 184 ? 0.30923   6.07732   42.39836  1.000 46.23944  ? 164 ASP A CG  1 
ATOM   2472 O  OD1 . ASP B 1 184 ? 0.23034   5.36248   43.42170  1.000 45.29603  ? 164 ASP A OD1 1 
ATOM   2473 O  OD2 . ASP B 1 184 ? -0.53714  6.95390   42.12274  1.000 46.90621  ? 164 ASP A OD2 1 
ATOM   2474 N  N   . GLY B 1 185 ? 3.17301   4.71769   44.35153  1.000 41.34616  ? 165 GLY A N   1 
ATOM   2475 C  CA  . GLY B 1 185 ? 3.59600   5.20157   45.64705  1.000 41.32332  ? 165 GLY A CA  1 
ATOM   2476 C  C   . GLY B 1 185 ? 2.51888   5.89543   46.44763  1.000 53.57166  ? 165 GLY A C   1 
ATOM   2477 O  O   . GLY B 1 185 ? 2.79011   6.33025   47.57545  1.000 52.63119  ? 165 GLY A O   1 
ATOM   2478 N  N   . GLN B 1 186 ? 1.30922   6.01609   45.90461  1.000 40.59438  ? 166 GLN A N   1 
ATOM   2479 C  CA  . GLN B 1 186 ? 0.20463   6.69069   46.57363  1.000 47.15476  ? 166 GLN A CA  1 
ATOM   2480 C  C   . GLN B 1 186 ? -1.07777  5.88639   46.41939  1.000 51.48315  ? 166 GLN A C   1 
ATOM   2481 O  O   . GLN B 1 186 ? -2.17000  6.44479   46.27214  1.000 49.69978  ? 166 GLN A O   1 
ATOM   2482 C  CB  . GLN B 1 186 ? 0.02472   8.11219   46.04227  1.000 50.71903  ? 166 GLN A CB  1 
ATOM   2483 C  CG  . GLN B 1 186 ? 1.18625   9.03650   46.37460  1.000 48.71630  ? 166 GLN A CG  1 
ATOM   2484 C  CD  . GLN B 1 186 ? 1.11087   10.36165  45.64618  1.000 57.53214  ? 166 GLN A CD  1 
ATOM   2485 O  OE1 . GLN B 1 186 ? 0.33781   10.52160  44.70069  1.000 69.86391  ? 166 GLN A OE1 1 
ATOM   2486 N  NE2 . GLN B 1 186 ? 1.91853   11.32238  46.08260  1.000 49.52189  ? 166 GLN A NE2 1 
ATOM   2487 N  N   . GLY B 1 187 ? -0.95840  4.55860   46.43900  1.000 39.61179  ? 167 GLY A N   1 
ATOM   2488 C  CA  . GLY B 1 187 ? -2.09587  3.67005   46.49254  1.000 41.46010  ? 167 GLY A CA  1 
ATOM   2489 C  C   . GLY B 1 187 ? -2.60374  3.17699   45.15201  1.000 47.56551  ? 167 GLY A C   1 
ATOM   2490 O  O   . GLY B 1 187 ? -3.17914  2.08552   45.08596  1.000 47.61335  ? 167 GLY A O   1 
ATOM   2491 N  N   . ARG B 1 188 ? -2.41267  3.94774   44.08511  1.000 39.93431  ? 168 ARG A N   1 
ATOM   2492 C  CA  . ARG B 1 188 ? -2.93326  3.55828   42.78299  1.000 40.76459  ? 168 ARG A CA  1 
ATOM   2493 C  C   . ARG B 1 188 ? -2.05030  2.49749   42.13732  1.000 42.46923  ? 168 ARG A C   1 
ATOM   2494 O  O   . ARG B 1 188 ? -0.83546  2.45266   42.34825  1.000 38.21880  ? 168 ARG A O   1 
ATOM   2495 C  CB  . ARG B 1 188 ? -3.04418  4.76953   41.85557  1.000 44.75080  ? 168 ARG A CB  1 
ATOM   2496 C  CG  . ARG B 1 188 ? -3.99374  5.84325   42.34851  1.000 52.36359  ? 168 ARG A CG  1 
ATOM   2497 C  CD  . ARG B 1 188 ? -4.21815  6.90593   41.28611  1.000 58.80032  ? 168 ARG A CD  1 
ATOM   2498 N  NE  . ARG B 1 188 ? -4.90110  8.07665   41.82209  1.000 54.98582  ? 168 ARG A NE  1 
ATOM   2499 C  CZ  . ARG B 1 188 ? -4.28725  9.08232   42.43115  1.000 72.89996  ? 168 ARG A CZ  1 
ATOM   2500 N  NH1 . ARG B 1 188 ? -2.97545  9.08603   42.60898  1.000 67.38682  ? 168 ARG A NH1 1 
ATOM   2501 N  NH2 . ARG B 1 188 ? -5.00662  10.10938  42.87455  1.000 69.32590  ? 168 ARG A NH2 1 
ATOM   2502 N  N   . ARG B 1 189 ? -2.68010  1.64113   41.33912  1.000 34.26481  ? 169 ARG A N   1 
ATOM   2503 C  CA  . ARG B 1 189 ? -2.00137  0.57848   40.61666  1.000 33.86835  ? 169 ARG A CA  1 
ATOM   2504 C  C   . ARG B 1 189 ? -2.30078  0.70699   39.12928  1.000 32.33291  ? 169 ARG A C   1 
ATOM   2505 O  O   . ARG B 1 189 ? -3.36355  1.19651   38.73667  1.000 34.49341  ? 169 ARG A O   1 
ATOM   2506 C  CB  . ARG B 1 189 ? -2.43551  -0.80301  41.13064  1.000 41.59119  ? 169 ARG A CB  1 
ATOM   2507 C  CG  . ARG B 1 189 ? -2.09511  -1.03989  42.59461  1.000 37.28762  ? 169 ARG A CG  1 
ATOM   2508 C  CD  . ARG B 1 189 ? -2.77292  -2.28102  43.16077  1.000 40.77999  ? 169 ARG A CD  1 
ATOM   2509 N  NE  . ARG B 1 189 ? -2.32625  -3.51328  42.51995  1.000 58.54139  ? 169 ARG A NE  1 
ATOM   2510 C  CZ  . ARG B 1 189 ? -3.13203  -4.39373  41.94087  1.000 55.78803  ? 169 ARG A CZ  1 
ATOM   2511 N  NH1 . ARG B 1 189 ? -4.44386  -4.22244  41.92098  1.000 57.26172  ? 169 ARG A NH1 1 
ATOM   2512 N  NH2 . ARG B 1 189 ? -2.60936  -5.47857  41.37657  1.000 52.83978  ? 169 ARG A NH2 1 
ATOM   2513 N  N   . ARG B 1 190 ? -1.35291  0.27437   38.29899  1.000 34.24834  ? 170 ARG A N   1 
ATOM   2514 C  CA  . ARG B 1 190 ? -1.53978  0.33353   36.85662  1.000 32.76721  ? 170 ARG A CA  1 
ATOM   2515 C  C   . ARG B 1 190 ? -0.74178  -0.77962  36.19166  1.000 33.89161  ? 170 ARG A C   1 
ATOM   2516 O  O   . ARG B 1 190 ? 0.28642   -1.22639  36.71057  1.000 30.68040  ? 170 ARG A O   1 
ATOM   2517 C  CB  . ARG B 1 190 ? -1.13437  1.70111   36.28993  1.000 27.24092  ? 170 ARG A CB  1 
ATOM   2518 C  CG  . ARG B 1 190 ? 0.35689   1.98568   36.32984  1.000 34.48548  ? 170 ARG A CG  1 
ATOM   2519 C  CD  . ARG B 1 190 ? 0.63692   3.41991   35.91665  1.000 32.54914  ? 170 ARG A CD  1 
ATOM   2520 N  NE  . ARG B 1 190 ? 2.04865   3.65896   35.64299  1.000 32.33178  ? 170 ARG A NE  1 
ATOM   2521 C  CZ  . ARG B 1 190 ? 2.92510   4.08678   36.54044  1.000 32.07635  ? 170 ARG A CZ  1 
ATOM   2522 N  NH1 . ARG B 1 190 ? 2.57833   4.29792   37.79933  1.000 31.38172  ? 170 ARG A NH1 1 
ATOM   2523 N  NH2 . ARG B 1 190 ? 4.18025   4.31269   36.16409  1.000 34.75244  ? 170 ARG A NH2 1 
ATOM   2524 N  N   . VAL B 1 191 ? -1.24265  -1.23166  35.03913  1.000 21.94650  ? 171 VAL A N   1 
ATOM   2525 C  CA  . VAL B 1 191 ? -0.60935  -2.27173  34.24060  1.000 25.03899  ? 171 VAL A CA  1 
ATOM   2526 C  C   . VAL B 1 191 ? -0.57738  -1.80410  32.79060  1.000 27.34744  ? 171 VAL A C   1 
ATOM   2527 O  O   . VAL B 1 191 ? -1.30799  -0.89498  32.38680  1.000 26.66037  ? 171 VAL A O   1 
ATOM   2528 C  CB  . VAL B 1 191 ? -1.33315  -3.63833  34.35210  1.000 29.80284  ? 171 VAL A CB  1 
ATOM   2529 C  CG1 . VAL B 1 191 ? -1.31039  -4.15167  35.79272  1.000 27.41125  ? 171 VAL A CG1 1 
ATOM   2530 C  CG2 . VAL B 1 191 ? -2.76412  -3.54171  33.82974  1.000 20.15579  ? 171 VAL A CG2 1 
ATOM   2531 N  N   . HIS B 1 192 ? 0.29058   -2.43588  32.00462  1.000 25.91781  ? 172 HIS A N   1 
ATOM   2532 C  CA  . HIS B 1 192 ? 0.48935   -2.07344  30.60650  1.000 34.70269  ? 172 HIS A CA  1 
ATOM   2533 C  C   . HIS B 1 192 ? 0.11071   -3.25467  29.72127  1.000 32.22680  ? 172 HIS A C   1 
ATOM   2534 O  O   . HIS B 1 192 ? 0.65047   -4.35817  29.88005  1.000 34.25086  ? 172 HIS A O   1 
ATOM   2535 C  CB  . HIS B 1 192 ? 1.93111   -1.61808  30.37369  1.000 36.81769  ? 172 HIS A CB  1 
ATOM   2536 C  CG  . HIS B 1 192 ? 2.29451   -0.38991  31.14988  1.000 37.79835  ? 172 HIS A CG  1 
ATOM   2537 N  ND1 . HIS B 1 192 ? 3.16144   -0.41411  32.22202  1.000 42.29041  ? 172 HIS A ND1 1 
ATOM   2538 C  CD2 . HIS B 1 192 ? 1.87508   0.89258   31.03354  1.000 34.32612  ? 172 HIS A CD2 1 
ATOM   2539 C  CE1 . HIS B 1 192 ? 3.27395   0.80364   32.72151  1.000 34.47279  ? 172 HIS A CE1 1 
ATOM   2540 N  NE2 . HIS B 1 192 ? 2.50395   1.61496   32.01818  1.000 40.75627  ? 172 HIS A NE2 1 
ATOM   2541 N  N   . LEU B 1 193 ? -0.83605  -3.02000  28.81388  1.000 34.47156  ? 173 LEU A N   1 
ATOM   2542 C  CA  . LEU B 1 193 ? -1.44584  -4.04221  27.98026  1.000 32.25851  ? 173 LEU A CA  1 
ATOM   2543 C  C   . LEU B 1 193 ? -1.11255  -3.80441  26.51376  1.000 29.51685  ? 173 LEU A C   1 
ATOM   2544 O  O   . LEU B 1 193 ? -0.93505  -2.66414  26.07233  1.000 28.70055  ? 173 LEU A O   1 
ATOM   2545 C  CB  . LEU B 1 193 ? -2.96861  -4.05227  28.15282  1.000 21.36543  ? 173 LEU A CB  1 
ATOM   2546 C  CG  . LEU B 1 193 ? -3.50067  -4.04200  29.58461  1.000 27.14929  ? 173 LEU A CG  1 
ATOM   2547 C  CD1 . LEU B 1 193 ? -5.01360  -3.89642  29.58729  1.000 27.57453  ? 173 LEU A CD1 1 
ATOM   2548 C  CD2 . LEU B 1 193 ? -3.07605  -5.30098  30.32888  1.000 31.92075  ? 173 LEU A CD2 1 
ATOM   2549 N  N   . HIS B 1 194 ? -1.07336  -4.90010  25.76163  1.000 31.20973  ? 174 HIS A N   1 
ATOM   2550 C  CA  . HIS B 1 194 ? -0.69865  -4.89673  24.35738  1.000 28.26655  ? 174 HIS A CA  1 
ATOM   2551 C  C   . HIS B 1 194 ? -1.60548  -5.86524  23.61581  1.000 30.49284  ? 174 HIS A C   1 
ATOM   2552 O  O   . HIS B 1 194 ? -1.72749  -7.02862  24.01268  1.000 31.56703  ? 174 HIS A O   1 
ATOM   2553 C  CB  . HIS B 1 194 ? 0.77270   -5.30372  24.20020  1.000 36.22671  ? 174 HIS A CB  1 
ATOM   2554 C  CG  . HIS B 1 194 ? 1.27768   -5.25774  22.79105  1.000 47.24219  ? 174 HIS A CG  1 
ATOM   2555 N  ND1 . HIS B 1 194 ? 0.92001   -6.18699  21.83605  1.000 35.68926  ? 174 HIS A ND1 1 
ATOM   2556 C  CD2 . HIS B 1 194 ? 2.14258   -4.40998  22.18550  1.000 45.97719  ? 174 HIS A CD2 1 
ATOM   2557 C  CE1 . HIS B 1 194 ? 1.53011   -5.90274  20.69916  1.000 43.02693  ? 174 HIS A CE1 1 
ATOM   2558 N  NE2 . HIS B 1 194 ? 2.27782   -4.82926  20.88457  1.000 51.91925  ? 174 HIS A NE2 1 
ATOM   2559 N  N   . LYS B 1 195 ? -2.24757  -5.39166  22.55194  1.000 30.68497  ? 175 LYS A N   1 
ATOM   2560 C  CA  . LYS B 1 195 ? -3.05052  -6.24811  21.68946  1.000 35.88763  ? 175 LYS A CA  1 
ATOM   2561 C  C   . LYS B 1 195 ? -2.49205  -6.19270  20.27764  1.000 36.61603  ? 175 LYS A C   1 
ATOM   2562 O  O   . LYS B 1 195 ? -2.34100  -5.10701  19.70810  1.000 34.09524  ? 175 LYS A O   1 
ATOM   2563 C  CB  . LYS B 1 195 ? -4.52186  -5.83557  21.68467  1.000 38.39730  ? 175 LYS A CB  1 
ATOM   2564 C  CG  . LYS B 1 195 ? -5.27690  -6.41279  20.49304  1.000 35.94873  ? 175 LYS A CG  1 
ATOM   2565 C  CD  . LYS B 1 195 ? -6.77657  -6.28767  20.66413  1.000 33.51404  ? 175 LYS A CD  1 
ATOM   2566 C  CE  . LYS B 1 195 ? -7.54173  -6.92747  19.50187  1.000 43.63095  ? 175 LYS A CE  1 
ATOM   2567 N  NZ  . LYS B 1 195 ? -7.53799  -8.42223  19.49045  1.000 39.41609  ? 175 LYS A NZ  1 
ATOM   2568 N  N   . SER B 1 196 ? -2.19427  -7.35927  19.71563  1.000 34.68464  ? 176 SER A N   1 
ATOM   2569 C  CA  . SER B 1 196 ? -1.73740  -7.42197  18.33739  1.000 40.83373  ? 176 SER A CA  1 
ATOM   2570 C  C   . SER B 1 196 ? -2.90300  -7.19669  17.38140  1.000 42.50072  ? 176 SER A C   1 
ATOM   2571 O  O   . SER B 1 196 ? -4.04086  -7.59328  17.64689  1.000 45.38351  ? 176 SER A O   1 
ATOM   2572 C  CB  . SER B 1 196 ? -1.07520  -8.76799  18.05618  1.000 38.47473  ? 176 SER A CB  1 
ATOM   2573 O  OG  . SER B 1 196 ? 0.00802   -8.98640  18.94201  1.000 57.67426  ? 176 SER A OG  1 
ATOM   2574 N  N   . LEU B 1 197 ? -2.60846  -6.54919  16.25888  1.000 44.66439  ? 177 LEU A N   1 
ATOM   2575 C  CA  . LEU B 1 197 ? -3.62381  -6.27214  15.25011  1.000 46.67671  ? 177 LEU A CA  1 
ATOM   2576 C  C   . LEU B 1 197 ? -3.36143  -7.06305  13.96934  1.000 54.02301  ? 177 LEU A C   1 
ATOM   2577 O  O   . LEU B 1 197 ? -2.35754  -7.76617  13.84031  1.000 52.36992  ? 177 LEU A O   1 
ATOM   2578 C  CB  . LEU B 1 197 ? -3.67938  -4.77322  14.94544  1.000 43.57776  ? 177 LEU A CB  1 
ATOM   2579 C  CG  . LEU B 1 197 ? -4.03961  -3.86271  16.12288  1.000 47.70135  ? 177 LEU A CG  1 
ATOM   2580 C  CD1 . LEU B 1 197 ? -4.02802  -2.39807  15.70627  1.000 36.43684  ? 177 LEU A CD1 1 
ATOM   2581 C  CD2 . LEU B 1 197 ? -5.39136  -4.24421  16.70811  1.000 40.50315  ? 177 LEU A CD2 1 
ATOM   2582 N  N   . ALA C 1 34  ? -9.60871  -19.97480 35.91089  1.000 60.17148  ? 14  ALA B N   1 
ATOM   2583 C  CA  . ALA C 1 34  ? -10.93050 -20.40705 36.35015  1.000 49.17879  ? 14  ALA B CA  1 
ATOM   2584 C  C   . ALA C 1 34  ? -11.86712 -20.60542 35.15846  1.000 50.30684  ? 14  ALA B C   1 
ATOM   2585 O  O   . ALA C 1 34  ? -12.90612 -21.25539 35.27796  1.000 53.39258  ? 14  ALA B O   1 
ATOM   2586 C  CB  . ALA C 1 34  ? -11.51753 -19.40264 37.33077  1.000 44.10091  ? 14  ALA B CB  1 
ATOM   2587 N  N   . TRP C 1 35  ? -11.49236 -20.03448 34.01501  1.000 38.10577  ? 15  TRP B N   1 
ATOM   2588 C  CA  . TRP C 1 35  ? -12.21341 -20.19872 32.75720  1.000 36.96996  ? 15  TRP B CA  1 
ATOM   2589 C  C   . TRP C 1 35  ? -11.34538 -21.02064 31.81480  1.000 43.45415  ? 15  TRP B C   1 
ATOM   2590 O  O   . TRP C 1 35  ? -10.25557 -20.57924 31.43495  1.000 45.40216  ? 15  TRP B O   1 
ATOM   2591 C  CB  . TRP C 1 35  ? -12.54553 -18.84448 32.12678  1.000 35.02329  ? 15  TRP B CB  1 
ATOM   2592 C  CG  . TRP C 1 35  ? -13.42688 -17.97319 32.96567  1.000 44.39691  ? 15  TRP B CG  1 
ATOM   2593 C  CD1 . TRP C 1 35  ? -13.03208 -17.11210 33.94795  1.000 45.85926  ? 15  TRP B CD1 1 
ATOM   2594 C  CD2 . TRP C 1 35  ? -14.85500 -17.87063 32.89245  1.000 43.20174  ? 15  TRP B CD2 1 
ATOM   2595 N  NE1 . TRP C 1 35  ? -14.12486 -16.48373 34.49410  1.000 43.61372  ? 15  TRP B NE1 1 
ATOM   2596 C  CE2 . TRP C 1 35  ? -15.25590 -16.93153 33.86379  1.000 41.23293  ? 15  TRP B CE2 1 
ATOM   2597 C  CE3 . TRP C 1 35  ? -15.83323 -18.48358 32.10230  1.000 39.17422  ? 15  TRP B CE3 1 
ATOM   2598 C  CZ2 . TRP C 1 35  ? -16.59201 -16.59047 34.06632  1.000 44.93572  ? 15  TRP B CZ2 1 
ATOM   2599 C  CZ3 . TRP C 1 35  ? -17.15891 -18.14420 32.30533  1.000 38.89746  ? 15  TRP B CZ3 1 
ATOM   2600 C  CH2 . TRP C 1 35  ? -17.52600 -17.20595 33.27885  1.000 49.14692  ? 15  TRP B CH2 1 
ATOM   2601 N  N   . GLN C 1 36  ? -11.82357 -22.20447 31.42891  1.000 33.62575  ? 16  GLN B N   1 
ATOM   2602 C  CA  . GLN C 1 36  ? -11.02390 -23.10651 30.60896  1.000 39.56895  ? 16  GLN B CA  1 
ATOM   2603 C  C   . GLN C 1 36  ? -11.82663 -23.61928 29.42235  1.000 37.02922  ? 16  GLN B C   1 
ATOM   2604 O  O   . GLN C 1 36  ? -13.01429 -23.92583 29.54805  1.000 30.83295  ? 16  GLN B O   1 
ATOM   2605 C  CB  . GLN C 1 36  ? -10.50777 -24.28812 31.43462  1.000 43.15875  ? 16  GLN B CB  1 
ATOM   2606 C  CG  . GLN C 1 36  ? -8.99578  -24.34029 31.54950  1.000 43.98206  ? 16  GLN B CG  1 
ATOM   2607 C  CD  . GLN C 1 36  ? -8.52640  -25.35848 32.56626  1.000 43.39447  ? 16  GLN B CD  1 
ATOM   2608 O  OE1 . GLN C 1 36  ? -9.24985  -25.69618 33.50475  1.000 50.02690  ? 16  GLN B OE1 1 
ATOM   2609 N  NE2 . GLN C 1 36  ? -7.31003  -25.85631 32.38465  1.000 52.23690  ? 16  GLN B NE2 1 
ATOM   2610 N  N   . TRP C 1 37  ? -11.16804 -23.72522 28.27297  1.000 34.77678  ? 17  TRP B N   1 
ATOM   2611 C  CA  . TRP C 1 37  ? -11.79587 -24.22846 27.06049  1.000 34.32748  ? 17  TRP B CA  1 
ATOM   2612 C  C   . TRP C 1 37  ? -11.43666 -25.69184 26.83887  1.000 37.39405  ? 17  TRP B C   1 
ATOM   2613 O  O   . TRP C 1 37  ? -10.37007 -26.16076 27.24587  1.000 35.41525  ? 17  TRP B O   1 
ATOM   2614 C  CB  . TRP C 1 37  ? -11.38271 -23.39791 25.84205  1.000 30.61236  ? 17  TRP B CB  1 
ATOM   2615 C  CG  . TRP C 1 37  ? -12.13011 -22.10664 25.74644  1.000 39.14834  ? 17  TRP B CG  1 
ATOM   2616 C  CD1 . TRP C 1 37  ? -11.70908 -20.88020 26.17290  1.000 28.93097  ? 17  TRP B CD1 1 
ATOM   2617 C  CD2 . TRP C 1 37  ? -13.44601 -21.91629 25.21019  1.000 32.43152  ? 17  TRP B CD2 1 
ATOM   2618 N  NE1 . TRP C 1 37  ? -12.67799 -19.93640 25.92549  1.000 38.97254  ? 17  TRP B NE1 1 
ATOM   2619 C  CE2 . TRP C 1 37  ? -13.75466 -20.54733 25.33714  1.000 38.95731  ? 17  TRP B CE2 1 
ATOM   2620 C  CE3 . TRP C 1 37  ? -14.39011 -22.76989 24.63056  1.000 34.27003  ? 17  TRP B CE3 1 
ATOM   2621 C  CZ2 . TRP C 1 37  ? -14.96876 -20.01204 24.90626  1.000 40.66442  ? 17  TRP B CZ2 1 
ATOM   2622 C  CZ3 . TRP C 1 37  ? -15.59489 -22.23664 24.20279  1.000 34.95901  ? 17  TRP B CZ3 1 
ATOM   2623 C  CH2 . TRP C 1 37  ? -15.87200 -20.87056 24.34041  1.000 34.66016  ? 17  TRP B CH2 1 
ATOM   2624 N  N   . GLU C 1 38  ? -12.35169 -26.41609 26.20034  1.000 39.35023  ? 18  GLU B N   1 
ATOM   2625 C  CA  . GLU C 1 38  ? -12.11403 -27.81618 25.89011  1.000 36.60321  ? 18  GLU B CA  1 
ATOM   2626 C  C   . GLU C 1 38  ? -12.90335 -28.18709 24.64485  1.000 37.71145  ? 18  GLU B C   1 
ATOM   2627 O  O   . GLU C 1 38  ? -13.90738 -27.55046 24.31459  1.000 32.56142  ? 18  GLU B O   1 
ATOM   2628 C  CB  . GLU C 1 38  ? -12.50515 -28.72808 27.06165  1.000 26.40564  ? 18  GLU B CB  1 
ATOM   2629 C  CG  . GLU C 1 38  ? -14.00384 -28.80934 27.30264  1.000 27.16247  ? 18  GLU B CG  1 
ATOM   2630 C  CD  . GLU C 1 38  ? -14.35905 -29.48269 28.61498  1.000 31.01906  ? 18  GLU B CD  1 
ATOM   2631 O  OE1 . GLU C 1 38  ? -13.80765 -29.08592 29.66385  1.000 29.05410  ? 18  GLU B OE1 1 
ATOM   2632 O  OE2 . GLU C 1 38  ? -15.19171 -30.41264 28.59664  1.000 40.07194  ? 18  GLU B OE2 1 
ATOM   2633 N  N   . VAL C 1 39  ? -12.42441 -29.20631 23.94024  1.000 36.01510  ? 19  VAL B N   1 
ATOM   2634 C  CA  . VAL C 1 39  ? -13.21189 -29.82897 22.88333  1.000 33.75026  ? 19  VAL B CA  1 
ATOM   2635 C  C   . VAL C 1 39  ? -14.16196 -30.81376 23.54634  1.000 34.45712  ? 19  VAL B C   1 
ATOM   2636 O  O   . VAL C 1 39  ? -13.72496 -31.77766 24.18381  1.000 32.20073  ? 19  VAL B O   1 
ATOM   2637 C  CB  . VAL C 1 39  ? -12.31778 -30.53074 21.85262  1.000 37.24408  ? 19  VAL B CB  1 
ATOM   2638 C  CG1 . VAL C 1 39  ? -13.17283 -31.27511 20.83607  1.000 30.26303  ? 19  VAL B CG1 1 
ATOM   2639 C  CG2 . VAL C 1 39  ? -11.42741 -29.52617 21.16022  1.000 36.02067  ? 19  VAL B CG2 1 
ATOM   2640 N  N   . SER C 1 40  ? -15.45963 -30.56466 23.41779  1.000 30.57030  ? 20  SER B N   1 
ATOM   2641 C  CA  . SER C 1 40  ? -16.43314 -31.41257 24.08512  1.000 35.51331  ? 20  SER B CA  1 
ATOM   2642 C  C   . SER C 1 40  ? -16.50100 -32.77946 23.41771  1.000 35.04936  ? 20  SER B C   1 
ATOM   2643 O  O   . SER C 1 40  ? -16.53489 -32.89091 22.18904  1.000 39.52016  ? 20  SER B O   1 
ATOM   2644 C  CB  . SER C 1 40  ? -17.81060 -30.75721 24.07625  1.000 36.62331  ? 20  SER B CB  1 
ATOM   2645 O  OG  . SER C 1 40  ? -18.72116 -31.52637 24.84019  1.000 34.65716  ? 20  SER B OG  1 
ATOM   2646 N  N   . ARG C 1 41  ? -16.51722 -33.82637 24.24320  1.000 38.00159  ? 21  ARG B N   1 
ATOM   2647 C  CA  . ARG C 1 41  ? -16.70762 -35.19447 23.77728  1.000 47.67366  ? 21  ARG B CA  1 
ATOM   2648 C  C   . ARG C 1 41  ? -17.90131 -35.85319 24.45818  1.000 45.63071  ? 21  ARG B C   1 
ATOM   2649 O  O   . ARG C 1 41  ? -18.02368 -37.08233 24.44591  1.000 53.90050  ? 21  ARG B O   1 
ATOM   2650 C  CB  . ARG C 1 41  ? -15.43478 -36.01388 23.99439  1.000 33.06761  ? 21  ARG B CB  1 
ATOM   2651 C  CG  . ARG C 1 41  ? -14.26117 -35.52804 23.16328  1.000 38.69844  ? 21  ARG B CG  1 
ATOM   2652 C  CD  . ARG C 1 41  ? -14.53266 -35.71776 21.67957  1.000 31.47234  ? 21  ARG B CD  1 
ATOM   2653 N  NE  . ARG C 1 41  ? -13.44328 -35.20719 20.85555  1.000 45.56965  ? 21  ARG B NE  1 
ATOM   2654 C  CZ  . ARG C 1 41  ? -13.32980 -35.41612 19.55063  1.000 49.79307  ? 21  ARG B CZ  1 
ATOM   2655 N  NH1 . ARG C 1 41  ? -14.21271 -36.14601 18.88762  1.000 49.09246  ? 21  ARG B NH1 1 
ATOM   2656 N  NH2 . ARG C 1 41  ? -12.30415 -34.88099 18.89450  1.000 34.48282  ? 21  ARG B NH2 1 
ATOM   2657 N  N   . ASP C 1 42  ? -18.78680 -35.05113 25.04576  1.000 40.22084  ? 22  ASP B N   1 
ATOM   2658 C  CA  . ASP C 1 42  ? -19.96276 -35.53072 25.76435  1.000 41.29645  ? 22  ASP B CA  1 
ATOM   2659 C  C   . ASP C 1 42  ? -21.19927 -35.02388 25.03188  1.000 40.60158  ? 22  ASP B C   1 
ATOM   2660 O  O   . ASP C 1 42  ? -21.51780 -33.83117 25.09433  1.000 48.35560  ? 22  ASP B O   1 
ATOM   2661 C  CB  . ASP C 1 42  ? -19.93937 -35.05032 27.21581  1.000 42.71889  ? 22  ASP B CB  1 
ATOM   2662 C  CG  . ASP C 1 42  ? -20.92639 -35.78795 28.09749  1.000 44.93436  ? 22  ASP B CG  1 
ATOM   2663 O  OD1 . ASP C 1 42  ? -21.93438 -36.30968 27.57625  1.000 47.37313  ? 22  ASP B OD1 1 
ATOM   2664 O  OD2 . ASP C 1 42  ? -20.69119 -35.84086 29.32237  1.000 56.02309  ? 22  ASP B OD2 1 
ATOM   2665 N  N   . THR C 1 43  ? -21.89620 -35.93066 24.34329  1.000 40.26651  ? 23  THR B N   1 
ATOM   2666 C  CA  . THR C 1 43  ? -23.06449 -35.53531 23.56078  1.000 35.47428  ? 23  THR B CA  1 
ATOM   2667 C  C   . THR C 1 43  ? -24.20796 -35.06779 24.45640  1.000 38.73398  ? 23  THR B C   1 
ATOM   2668 O  O   . THR C 1 43  ? -24.85473 -34.05027 24.16951  1.000 35.95315  ? 23  THR B O   1 
ATOM   2669 C  CB  . THR C 1 43  ? -23.51515 -36.69980 22.67612  1.000 36.47572  ? 23  THR B CB  1 
ATOM   2670 O  OG1 . THR C 1 43  ? -22.54303 -36.92537 21.64621  1.000 40.83898  ? 23  THR B OG1 1 
ATOM   2671 C  CG2 . THR C 1 43  ? -24.86436 -36.40468 22.03695  1.000 34.32974  ? 23  THR B CG2 1 
ATOM   2672 N  N   . GLY C 1 44  ? -24.47081 -35.79685 25.54404  1.000 35.93417  ? 24  GLY B N   1 
ATOM   2673 C  CA  . GLY C 1 44  ? -25.56715 -35.42761 26.42538  1.000 38.68661  ? 24  GLY B CA  1 
ATOM   2674 C  C   . GLY C 1 44  ? -25.38132 -34.06385 27.06294  1.000 39.75169  ? 24  GLY B C   1 
ATOM   2675 O  O   . GLY C 1 44  ? -26.32662 -33.27576 27.14532  1.000 39.31782  ? 24  GLY B O   1 
ATOM   2676 N  N   . GLU C 1 45  ? -24.16063 -33.76508 27.51883  1.000 38.95049  ? 25  GLU B N   1 
ATOM   2677 C  CA  . GLU C 1 45  ? -23.88773 -32.46527 28.12813  1.000 36.14724  ? 25  GLU B CA  1 
ATOM   2678 C  C   . GLU C 1 45  ? -24.11430 -31.33263 27.13307  1.000 39.50091  ? 25  GLU B C   1 
ATOM   2679 O  O   . GLU C 1 45  ? -24.75202 -30.32079 27.45658  1.000 35.01055  ? 25  GLU B O   1 
ATOM   2680 C  CB  . GLU C 1 45  ? -22.45580 -32.43501 28.66790  1.000 38.20755  ? 25  GLU B CB  1 
ATOM   2681 C  CG  . GLU C 1 45  ? -22.10996 -31.20091 29.48889  1.000 43.54839  ? 25  GLU B CG  1 
ATOM   2682 C  CD  . GLU C 1 45  ? -20.75960 -31.31587 30.17211  1.000 49.16309  ? 25  GLU B CD  1 
ATOM   2683 O  OE1 . GLU C 1 45  ? -19.77530 -31.67605 29.49359  1.000 46.44520  ? 25  GLU B OE1 1 
ATOM   2684 O  OE2 . GLU C 1 45  ? -20.68520 -31.06551 31.39487  1.000 53.10740  ? 25  GLU B OE2 1 
ATOM   2685 N  N   . VAL C 1 46  ? -23.60151 -31.49409 25.91125  1.000 34.23671  ? 26  VAL B N   1 
ATOM   2686 C  CA  . VAL C 1 46  ? -23.76172 -30.47138 24.88364  1.000 30.68359  ? 26  VAL B CA  1 
ATOM   2687 C  C   . VAL C 1 46  ? -25.23549 -30.25494 24.57429  1.000 30.25240  ? 26  VAL B C   1 
ATOM   2688 O  O   . VAL C 1 46  ? -25.71304 -29.11535 24.51283  1.000 31.21416  ? 26  VAL B O   1 
ATOM   2689 C  CB  . VAL C 1 46  ? -22.96926 -30.85629 23.62201  1.000 33.29900  ? 26  VAL B CB  1 
ATOM   2690 C  CG1 . VAL C 1 46  ? -23.42766 -30.02672 22.43350  1.000 22.15736  ? 26  VAL B CG1 1 
ATOM   2691 C  CG2 . VAL C 1 46  ? -21.49479 -30.65513 23.86012  1.000 28.65901  ? 26  VAL B CG2 1 
ATOM   2692 N  N   . HIS C 1 47  ? -25.97797 -31.34480 24.36699  1.000 33.94176  ? 27  HIS B N   1 
ATOM   2693 C  CA  . HIS C 1 47  ? -27.38064 -31.19942 23.99362  1.000 32.75818  ? 27  HIS B CA  1 
ATOM   2694 C  C   . HIS C 1 47  ? -28.19192 -30.56824 25.11856  1.000 30.62102  ? 27  HIS B C   1 
ATOM   2695 O  O   . HIS C 1 47  ? -29.03885 -29.70082 24.86619  1.000 30.13234  ? 27  HIS B O   1 
ATOM   2696 C  CB  . HIS C 1 47  ? -27.96851 -32.55206 23.59734  1.000 33.99108  ? 27  HIS B CB  1 
ATOM   2697 C  CG  . HIS C 1 47  ? -29.19256 -32.44645 22.74247  1.000 36.40705  ? 27  HIS B CG  1 
ATOM   2698 N  ND1 . HIS C 1 47  ? -29.13390 -32.20892 21.38560  1.000 32.53300  ? 27  HIS B ND1 1 
ATOM   2699 C  CD2 . HIS C 1 47  ? -30.50770 -32.53085 23.05340  1.000 35.74564  ? 27  HIS B CD2 1 
ATOM   2700 C  CE1 . HIS C 1 47  ? -30.36004 -32.16106 20.89618  1.000 39.25561  ? 27  HIS B CE1 1 
ATOM   2701 N  NE2 . HIS C 1 47  ? -31.21206 -32.35222 21.88754  1.000 40.02849  ? 27  HIS B NE2 1 
ATOM   2702 N  N   . ALA C 1 48  ? -27.94346 -30.97969 26.36618  1.000 31.32726  ? 28  ALA B N   1 
ATOM   2703 C  CA  . ALA C 1 48  ? -28.65993 -30.39038 27.49199  1.000 33.61588  ? 28  ALA B CA  1 
ATOM   2704 C  C   . ALA C 1 48  ? -28.36200 -28.90314 27.61792  1.000 34.51190  ? 28  ALA B C   1 
ATOM   2705 O  O   . ALA C 1 48  ? -29.27482 -28.09793 27.83873  1.000 34.19763  ? 28  ALA B O   1 
ATOM   2706 C  CB  . ALA C 1 48  ? -28.29712 -31.11945 28.78378  1.000 37.89861  ? 28  ALA B CB  1 
ATOM   2707 N  N   . MET C 1 49  ? -27.08884 -28.51990 27.47986  1.000 29.20050  ? 29  MET B N   1 
ATOM   2708 C  CA  . MET C 1 49  ? -26.71824 -27.10986 27.55791  1.000 30.40587  ? 29  MET B CA  1 
ATOM   2709 C  C   . MET C 1 49  ? -27.39018 -26.30129 26.45192  1.000 29.83221  ? 29  MET B C   1 
ATOM   2710 O  O   . MET C 1 49  ? -27.94684 -25.21957 26.69954  1.000 29.60076  ? 29  MET B O   1 
ATOM   2711 C  CB  . MET C 1 49  ? -25.19158 -26.98886 27.49372  1.000 34.31182  ? 29  MET B CB  1 
ATOM   2712 C  CG  . MET C 1 49  ? -24.64501 -25.62248 27.09761  1.000 28.37317  ? 29  MET B CG  1 
ATOM   2713 S  SD  . MET C 1 49  ? -25.10842 -24.29964 28.22477  1.000 64.09804  ? 29  MET B SD  1 
ATOM   2714 C  CE  . MET C 1 49  ? -24.87089 -25.10719 29.81448  1.000 48.91965  ? 29  MET B CE  1 
ATOM   2715 N  N   . LEU C 1 50  ? -27.35618 -26.82382 25.22304  1.000 30.50068  ? 30  LEU B N   1 
ATOM   2716 C  CA  . LEU C 1 50  ? -27.98724 -26.14606 24.09717  1.000 29.02797  ? 30  LEU B CA  1 
ATOM   2717 C  C   . LEU C 1 50  ? -29.47629 -25.93893 24.34549  1.000 32.87204  ? 30  LEU B C   1 
ATOM   2718 O  O   . LEU C 1 50  ? -30.00081 -24.83465 24.15718  1.000 26.92397  ? 30  LEU B O   1 
ATOM   2719 C  CB  . LEU C 1 50  ? -27.75585 -26.95081 22.81662  1.000 25.67607  ? 30  LEU B CB  1 
ATOM   2720 C  CG  . LEU C 1 50  ? -28.34162 -26.39162 21.51763  1.000 27.76979  ? 30  LEU B CG  1 
ATOM   2721 C  CD1 . LEU C 1 50  ? -27.75191 -25.02360 21.20798  1.000 26.45299  ? 30  LEU B CD1 1 
ATOM   2722 C  CD2 . LEU C 1 50  ? -28.10553 -27.35899 20.36558  1.000 25.27574  ? 30  LEU B CD2 1 
ATOM   2723 N  N   . CYS C 1 51  ? -30.17314 -26.99044 24.78741  1.000 27.85991  ? 31  CYS B N   1 
ATOM   2724 C  CA  . CYS C 1 51  ? -31.61575 -26.88150 24.97945  1.000 30.04502  ? 31  CYS B CA  1 
ATOM   2725 C  C   . CYS C 1 51  ? -31.96540 -25.96847 26.14503  1.000 29.23849  ? 31  CYS B C   1 
ATOM   2726 O  O   . CYS C 1 51  ? -32.96863 -25.24860 26.08139  1.000 32.67843  ? 31  CYS B O   1 
ATOM   2727 C  CB  . CYS C 1 51  ? -32.22806 -28.26624 25.18039  1.000 28.06296  ? 31  CYS B CB  1 
ATOM   2728 S  SG  . CYS C 1 51  ? -32.16747 -29.29788 23.70175  1.000 38.65287  ? 31  CYS B SG  1 
ATOM   2729 N  N   . ALA C 1 52  ? -31.15583 -25.96969 27.20699  1.000 32.25763  ? 32  ALA B N   1 
ATOM   2730 C  CA  . ALA C 1 52  ? -31.41172 -25.06497 28.32361  1.000 30.92058  ? 32  ALA B CA  1 
ATOM   2731 C  C   . ALA C 1 52  ? -31.26014 -23.60844 27.89602  1.000 27.16693  ? 32  ALA B C   1 
ATOM   2732 O  O   . ALA C 1 52  ? -32.10781 -22.75938 28.21737  1.000 34.85401  ? 32  ALA B O   1 
ATOM   2733 C  CB  . ALA C 1 52  ? -30.47536 -25.39167 29.48733  1.000 30.23447  ? 32  ALA B CB  1 
ATOM   2734 N  N   . CYS C 1 53  ? -30.17578 -23.29744 27.17493  1.000 29.37683  ? 33  CYS B N   1 
ATOM   2735 C  CA  . CYS C 1 53  ? -29.99634 -21.93608 26.68029  1.000 29.19431  ? 33  CYS B CA  1 
ATOM   2736 C  C   . CYS C 1 53  ? -31.12627 -21.54262 25.73874  1.000 27.29971  ? 33  CYS B C   1 
ATOM   2737 O  O   . CYS C 1 53  ? -31.63468 -20.41595 25.80561  1.000 31.05400  ? 33  CYS B O   1 
ATOM   2738 C  CB  . CYS C 1 53  ? -28.64433 -21.79797 25.98258  1.000 32.24274  ? 33  CYS B CB  1 
ATOM   2739 S  SG  . CYS C 1 53  ? -28.30804 -20.13675 25.34140  1.000 33.64563  ? 33  CYS B SG  1 
ATOM   2740 N  N   . ASP C 1 54  ? -31.53384 -22.46141 24.85760  1.000 31.14341  ? 34  ASP B N   1 
ATOM   2741 C  CA  . ASP C 1 54  ? -32.65018 -22.19467 23.95703  1.000 31.62223  ? 34  ASP B CA  1 
ATOM   2742 C  C   . ASP C 1 54  ? -33.91466 -21.85701 24.73513  1.000 32.70834  ? 34  ASP B C   1 
ATOM   2743 O  O   . ASP C 1 54  ? -34.61960 -20.89824 24.40517  1.000 26.85779  ? 34  ASP B O   1 
ATOM   2744 C  CB  . ASP C 1 54  ? -32.89634 -23.40195 23.04999  1.000 29.18893  ? 34  ASP B CB  1 
ATOM   2745 C  CG  . ASP C 1 54  ? -31.82846 -23.56962 21.99390  1.000 34.10403  ? 34  ASP B CG  1 
ATOM   2746 O  OD1 . ASP C 1 54  ? -31.15805 -22.57293 21.66486  1.000 35.36215  ? 34  ASP B OD1 1 
ATOM   2747 O  OD2 . ASP C 1 54  ? -31.66190 -24.70412 21.49648  1.000 37.10812  ? 34  ASP B OD2 1 
ATOM   2748 N  N   . ALA C 1 55  ? -34.21895 -22.64415 25.77152  1.000 32.13612  ? 35  ALA B N   1 
ATOM   2749 C  CA  . ALA C 1 55  ? -35.42166 -22.41145 26.56549  1.000 33.50669  ? 35  ALA B CA  1 
ATOM   2750 C  C   . ALA C 1 55  ? -35.39590 -21.03499 27.21488  1.000 33.32075  ? 35  ALA B C   1 
ATOM   2751 O  O   . ALA C 1 55  ? -36.37492 -20.27724 27.13979  1.000 29.40695  ? 35  ALA B O   1 
ATOM   2752 C  CB  . ALA C 1 55  ? -35.56071 -23.49884 27.62823  1.000 29.73767  ? 35  ALA B CB  1 
ATOM   2753 N  N   . HIS C 1 56  ? -34.28158 -20.69548 27.86795  1.000 30.50659  ? 36  HIS B N   1 
ATOM   2754 C  CA  . HIS C 1 56  ? -34.22507 -19.40718 28.55167  1.000 33.70211  ? 36  HIS B CA  1 
ATOM   2755 C  C   . HIS C 1 56  ? -34.30355 -18.24641 27.56457  1.000 34.67257  ? 36  HIS B C   1 
ATOM   2756 O  O   . HIS C 1 56  ? -35.01487 -17.26610 27.81323  1.000 42.76290  ? 36  HIS B O   1 
ATOM   2757 C  CB  . HIS C 1 56  ? -32.96977 -19.31541 29.41726  1.000 28.78029  ? 36  HIS B CB  1 
ATOM   2758 C  CG  . HIS C 1 56  ? -33.16693 -19.83157 30.80961  1.000 32.09491  ? 36  HIS B CG  1 
ATOM   2759 N  ND1 . HIS C 1 56  ? -32.93873 -21.14556 31.15744  1.000 30.09844  ? 36  HIS B ND1 1 
ATOM   2760 C  CD2 . HIS C 1 56  ? -33.59198 -19.21339 31.93697  1.000 24.43838  ? 36  HIS B CD2 1 
ATOM   2761 C  CE1 . HIS C 1 56  ? -33.20362 -21.31176 32.44116  1.000 29.10400  ? 36  HIS B CE1 1 
ATOM   2762 N  NE2 . HIS C 1 56  ? -33.60309 -20.15507 32.93727  1.000 22.01311  ? 36  HIS B NE2 1 
ATOM   2763 N  N   . GLN C 1 57  ? -33.61072 -18.34329 26.42684  1.000 35.81994  ? 37  GLN B N   1 
ATOM   2764 C  CA  . GLN C 1 57  ? -33.67002 -17.25430 25.45723  1.000 33.35838  ? 37  GLN B CA  1 
ATOM   2765 C  C   . GLN C 1 57  ? -35.04334 -17.14538 24.80524  1.000 38.42902  ? 37  GLN B C   1 
ATOM   2766 O  O   . GLN C 1 57  ? -35.49431 -16.03417 24.50471  1.000 45.69279  ? 37  GLN B O   1 
ATOM   2767 C  CB  . GLN C 1 57  ? -32.58159 -17.42619 24.40105  1.000 35.25676  ? 37  GLN B CB  1 
ATOM   2768 C  CG  . GLN C 1 57  ? -31.18999 -17.09475 24.91513  1.000 33.70123  ? 37  GLN B CG  1 
ATOM   2769 C  CD  . GLN C 1 57  ? -30.13911 -17.16602 23.83030  1.000 52.08621  ? 37  GLN B CD  1 
ATOM   2770 O  OE1 . GLN C 1 57  ? -30.22444 -17.99211 22.91882  1.000 45.09875  ? 37  GLN B OE1 1 
ATOM   2771 N  NE2 . GLN C 1 57  ? -29.13949 -16.29559 23.91867  1.000 50.62827  ? 37  GLN B NE2 1 
ATOM   2772 N  N   . ALA C 1 58  ? -35.72952 -18.27079 24.59442  1.000 37.42876  ? 38  ALA B N   1 
ATOM   2773 C  CA  . ALA C 1 58  ? -37.07800 -18.21897 24.04334  1.000 36.11144  ? 38  ALA B CA  1 
ATOM   2774 C  C   . ALA C 1 58  ? -38.04193 -17.56113 25.01896  1.000 36.44976  ? 38  ALA B C   1 
ATOM   2775 O  O   . ALA C 1 58  ? -38.87744 -16.74335 24.61836  1.000 40.28304  ? 38  ALA B O   1 
ATOM   2776 C  CB  . ALA C 1 58  ? -37.55293 -19.62635 23.68647  1.000 38.50294  ? 38  ALA B CB  1 
ATOM   2777 N  N   . ALA C 1 59  ? -37.93367 -17.89269 26.30699  1.000 31.46943  ? 39  ALA B N   1 
ATOM   2778 C  CA  . ALA C 1 59  ? -38.79353 -17.24703 27.29416  1.000 36.29143  ? 39  ALA B CA  1 
ATOM   2779 C  C   . ALA C 1 59  ? -38.48790 -15.75844 27.40065  1.000 41.16920  ? 39  ALA B C   1 
ATOM   2780 O  O   . ALA C 1 59  ? -39.40492 -14.93385 27.50207  1.000 46.25444  ? 39  ALA B O   1 
ATOM   2781 C  CB  . ALA C 1 59  ? -38.64140 -17.92505 28.65494  1.000 35.77541  ? 39  ALA B CB  1 
ATOM   2782 N  N   . ALA C 1 60  ? -37.20363 -15.39236 27.36017  1.000 43.07799  ? 40  ALA B N   1 
ATOM   2783 C  CA  . ALA C 1 60  ? -36.83192 -13.99458 27.54874  1.000 45.79044  ? 40  ALA B CA  1 
ATOM   2784 C  C   . ALA C 1 60  ? -37.14016 -13.14271 26.32125  1.000 44.65821  ? 40  ALA B C   1 
ATOM   2785 O  O   . ALA C 1 60  ? -37.37990 -11.93717 26.45469  1.000 51.42200  ? 40  ALA B O   1 
ATOM   2786 C  CB  . ALA C 1 60  ? -35.34856 -13.89152 27.90569  1.000 39.02437  ? 40  ALA B CB  1 
ATOM   2787 N  N   . SER C 1 61  ? -37.14142 -13.73373 25.12779  1.000 36.20623  ? 41  SER B N   1 
ATOM   2788 C  CA  . SER C 1 61  ? -37.32742 -12.97626 23.89728  1.000 43.97778  ? 41  SER B CA  1 
ATOM   2789 C  C   . SER C 1 61  ? -38.71896 -13.12495 23.29635  1.000 53.91871  ? 41  SER B C   1 
ATOM   2790 O  O   . SER C 1 61  ? -38.97115 -12.57816 22.21797  1.000 48.69675  ? 41  SER B O   1 
ATOM   2791 C  CB  . SER C 1 61  ? -36.28341 -13.39543 22.86060  1.000 46.82407  ? 41  SER B CB  1 
ATOM   2792 O  OG  . SER C 1 61  ? -36.45472 -14.75562 22.50824  1.000 55.38119  ? 41  SER B OG  1 
ATOM   2793 N  N   . GLY C 1 62  ? -39.62067 -13.85255 23.95105  1.000 49.56080  ? 42  GLY B N   1 
ATOM   2794 C  CA  . GLY C 1 62  ? -40.96374 -14.00284 23.42747  1.000 49.35829  ? 42  GLY B CA  1 
ATOM   2795 C  C   . GLY C 1 62  ? -41.08778 -14.88833 22.20845  1.000 52.05913  ? 42  GLY B C   1 
ATOM   2796 O  O   . GLY C 1 62  ? -42.05912 -14.75859 21.45891  1.000 53.96660  ? 42  GLY B O   1 
ATOM   2797 N  N   . THR C 1 63  ? -40.13159 -15.78482 21.98356  1.000 57.44549  ? 43  THR B N   1 
ATOM   2798 C  CA  . THR C 1 63  ? -40.17118 -16.73880 20.88659  1.000 40.29300  ? 43  THR B CA  1 
ATOM   2799 C  C   . THR C 1 63  ? -40.27880 -18.15654 21.44503  1.000 48.55419  ? 43  THR B C   1 
ATOM   2800 O  O   . THR C 1 63  ? -40.44134 -18.36482 22.65379  1.000 49.94862  ? 43  THR B O   1 
ATOM   2801 C  CB  . THR C 1 63  ? -38.93611 -16.58313 19.99255  1.000 49.46898  ? 43  THR B CB  1 
ATOM   2802 O  OG1 . THR C 1 63  ? -37.75170 -16.57594 20.80133  1.000 49.26619  ? 43  THR B OG1 1 
ATOM   2803 C  CG2 . THR C 1 63  ? -39.01130 -15.29442 19.18635  1.000 54.81268  ? 43  THR B CG2 1 
ATOM   2804 N  N   . SER C 1 64  ? -40.18996 -19.13924 20.55491  1.000 43.79335  ? 44  SER B N   1 
ATOM   2805 C  CA  . SER C 1 64  ? -40.16607 -20.54388 20.93187  1.000 45.77239  ? 44  SER B CA  1 
ATOM   2806 C  C   . SER C 1 64  ? -38.80737 -21.13257 20.58063  1.000 43.61687  ? 44  SER B C   1 
ATOM   2807 O  O   . SER C 1 64  ? -38.22059 -20.78917 19.54929  1.000 47.85838  ? 44  SER B O   1 
ATOM   2808 C  CB  . SER C 1 64  ? -41.28120 -21.32814 20.23185  1.000 47.81275  ? 44  SER B CB  1 
ATOM   2809 O  OG  . SER C 1 64  ? -41.10384 -21.33734 18.82653  1.000 49.16192  ? 44  SER B OG  1 
ATOM   2810 N  N   . ALA C 1 65  ? -38.30465 -22.00438 21.44788  1.000 44.52511  ? 45  ALA B N   1 
ATOM   2811 C  CA  . ALA C 1 65  ? -37.00152 -22.60440 21.21350  1.000 45.96010  ? 45  ALA B CA  1 
ATOM   2812 C  C   . ALA C 1 65  ? -37.06143 -23.52845 19.99918  1.000 47.92577  ? 45  ALA B C   1 
ATOM   2813 O  O   . ALA C 1 65  ? -38.05253 -24.24006 19.80657  1.000 49.19449  ? 45  ALA B O   1 
ATOM   2814 C  CB  . ALA C 1 65  ? -36.53654 -23.38217 22.44290  1.000 35.94731  ? 45  ALA B CB  1 
ATOM   2815 N  N   . PRO C 1 66  ? -36.03198 -23.52898 19.15718  1.000 52.06886  ? 46  PRO B N   1 
ATOM   2816 C  CA  . PRO C 1 66  ? -36.03767 -24.41286 17.98790  1.000 46.76455  ? 46  PRO B CA  1 
ATOM   2817 C  C   . PRO C 1 66  ? -35.83849 -25.86776 18.38460  1.000 48.50710  ? 46  PRO B C   1 
ATOM   2818 O  O   . PRO C 1 66  ? -35.29859 -26.19137 19.44515  1.000 46.46316  ? 46  PRO B O   1 
ATOM   2819 C  CB  . PRO C 1 66  ? -34.86281 -23.90038 17.14803  1.000 51.70360  ? 46  PRO B CB  1 
ATOM   2820 C  CG  . PRO C 1 66  ? -33.94884 -23.26199 18.13922  1.000 44.25806  ? 46  PRO B CG  1 
ATOM   2821 C  CD  . PRO C 1 66  ? -34.83602 -22.66922 19.20025  1.000 39.45205  ? 46  PRO B CD  1 
ATOM   2822 N  N   . ALA C 1 67  ? -36.29585 -26.75530 17.50606  1.000 50.53517  ? 47  ALA B N   1 
ATOM   2823 C  CA  . ALA C 1 67  ? -36.12765 -28.18731 17.71645  1.000 51.32048  ? 47  ALA B CA  1 
ATOM   2824 C  C   . ALA C 1 67  ? -34.70688 -28.58863 17.34172  1.000 42.18734  ? 47  ALA B C   1 
ATOM   2825 O  O   . ALA C 1 67  ? -34.26448 -28.34569 16.21406  1.000 49.04228  ? 47  ALA B O   1 
ATOM   2826 C  CB  . ALA C 1 67  ? -37.14538 -28.97475 16.89653  1.000 40.70628  ? 47  ALA B CB  1 
ATOM   2827 N  N   . ARG C 1 68  ? -33.98992 -29.18915 18.28616  1.000 41.25196  ? 48  ARG B N   1 
ATOM   2828 C  CA  . ARG C 1 68  ? -32.60613 -29.59511 18.08056  1.000 42.18529  ? 48  ARG B CA  1 
ATOM   2829 C  C   . ARG C 1 68  ? -32.54517 -31.09961 17.84899  1.000 39.83765  ? 48  ARG B C   1 
ATOM   2830 O  O   . ARG C 1 68  ? -33.17704 -31.86940 18.57989  1.000 42.76504  ? 48  ARG B O   1 
ATOM   2831 C  CB  . ARG C 1 68  ? -31.74126 -29.20979 19.28261  1.000 34.24466  ? 48  ARG B CB  1 
ATOM   2832 C  CG  . ARG C 1 68  ? -31.80617 -27.73649 19.66816  1.000 39.88495  ? 48  ARG B CG  1 
ATOM   2833 C  CD  . ARG C 1 68  ? -31.18805 -26.83418 18.60887  1.000 29.90227  ? 48  ARG B CD  1 
ATOM   2834 N  NE  . ARG C 1 68  ? -31.03048 -25.46986 19.10021  1.000 34.20890  ? 48  ARG B NE  1 
ATOM   2835 C  CZ  . ARG C 1 68  ? -30.45674 -24.48340 18.42314  1.000 37.85360  ? 48  ARG B CZ  1 
ATOM   2836 N  NH1 . ARG C 1 68  ? -29.96424 -24.67054 17.20921  1.000 36.53396  ? 48  ARG B NH1 1 
ATOM   2837 N  NH2 . ARG C 1 68  ? -30.37328 -23.27819 18.97929  1.000 26.84520  ? 48  ARG B NH2 1 
ATOM   2838 N  N   . ARG C 1 69  ? -31.78819 -31.51409 16.83508  1.000 44.42609  ? 49  ARG B N   1 
ATOM   2839 C  CA  . ARG C 1 69  ? -31.59862 -32.92861 16.53566  1.000 41.08208  ? 49  ARG B CA  1 
ATOM   2840 C  C   . ARG C 1 69  ? -30.45331 -33.47991 17.37601  1.000 40.61047  ? 49  ARG B C   1 
ATOM   2841 O  O   . ARG C 1 69  ? -29.32321 -32.98622 17.29376  1.000 38.00592  ? 49  ARG B O   1 
ATOM   2842 C  CB  . ARG C 1 69  ? -31.31031 -33.13934 15.05014  1.000 41.23270  ? 49  ARG B CB  1 
ATOM   2843 C  CG  . ARG C 1 69  ? -32.54133 -33.30135 14.17472  1.000 47.38789  ? 49  ARG B CG  1 
ATOM   2844 C  CD  . ARG C 1 69  ? -32.14122 -33.38055 12.70883  1.000 60.42066  ? 49  ARG B CD  1 
ATOM   2845 N  NE  . ARG C 1 69  ? -31.17875 -34.45005 12.46798  1.000 67.44368  ? 49  ARG B NE  1 
ATOM   2846 C  CZ  . ARG C 1 69  ? -30.39109 -34.52571 11.40337  1.000 71.41844  ? 49  ARG B CZ  1 
ATOM   2847 N  NH1 . ARG C 1 69  ? -30.41884 -33.60297 10.45528  1.000 60.58536  ? 49  ARG B NH1 1 
ATOM   2848 N  NH2 . ARG C 1 69  ? -29.54790 -35.54820 11.29136  1.000 56.02102  ? 49  ARG B NH2 1 
ATOM   2849 N  N   . MET C 1 70  ? -30.74913 -34.50467 18.17992  1.000 47.32950  ? 50  MET B N   1 
ATOM   2850 C  CA  . MET C 1 70  ? -29.70096 -35.21148 18.91002  1.000 44.05511  ? 50  MET B CA  1 
ATOM   2851 C  C   . MET C 1 70  ? -28.64237 -35.77542 17.96844  1.000 39.64940  ? 50  MET B C   1 
ATOM   2852 O  O   . MET C 1 70  ? -27.45303 -35.80443 18.31359  1.000 44.93368  ? 50  MET B O   1 
ATOM   2853 C  CB  . MET C 1 70  ? -30.32300 -36.33295 19.74579  1.000 46.76377  ? 50  MET B CB  1 
ATOM   2854 C  CG  . MET C 1 70  ? -29.32147 -37.24789 20.43038  1.000 50.28073  ? 50  MET B CG  1 
ATOM   2855 S  SD  . MET C 1 70  ? -28.50113 -36.47102 21.83232  1.000 66.91461  ? 50  MET B SD  1 
ATOM   2856 C  CE  . MET C 1 70  ? -29.87648 -36.30987 22.97223  1.000 63.55768  ? 50  MET B CE  1 
ATOM   2857 N  N   . GLU C 1 71  ? -29.05413 -36.22362 16.77831  1.000 46.81409  ? 51  GLU B N   1 
ATOM   2858 C  CA  . GLU C 1 71  ? -28.10530 -36.78080 15.81982  1.000 47.20904  ? 51  GLU B CA  1 
ATOM   2859 C  C   . GLU C 1 71  ? -27.09472 -35.73062 15.37386  1.000 42.50922  ? 51  GLU B C   1 
ATOM   2860 O  O   . GLU C 1 71  ? -25.89727 -36.01999 15.26512  1.000 42.06246  ? 51  GLU B O   1 
ATOM   2861 C  CB  . GLU C 1 71  ? -28.84830 -37.35713 14.61020  1.000 41.35140  ? 51  GLU B CB  1 
ATOM   2862 C  CG  . GLU C 1 71  ? -29.83421 -38.48554 14.91613  1.000 59.61862  ? 51  GLU B CG  1 
ATOM   2863 C  CD  . GLU C 1 71  ? -31.16493 -37.99153 15.46837  1.000 64.99709  ? 51  GLU B CD  1 
ATOM   2864 O  OE1 . GLU C 1 71  ? -31.54790 -38.42876 16.57459  1.000 59.49881  ? 51  GLU B OE1 1 
ATOM   2865 O  OE2 . GLU C 1 71  ? -31.82590 -37.16605 14.80057  1.000 62.03119  ? 51  GLU B OE2 1 
ATOM   2866 N  N   . THR C 1 72  ? -27.55959 -34.50564 15.10669  1.000 37.88131  ? 52  THR B N   1 
ATOM   2867 C  CA  . THR C 1 72  ? -26.64352 -33.42360 14.75871  1.000 44.28364  ? 52  THR B CA  1 
ATOM   2868 C  C   . THR C 1 72  ? -25.66285 -33.15546 15.89192  1.000 41.35835  ? 52  THR B C   1 
ATOM   2869 O  O   . THR C 1 72  ? -24.47467 -32.90222 15.65225  1.000 36.61208  ? 52  THR B O   1 
ATOM   2870 C  CB  . THR C 1 72  ? -27.42999 -32.15547 14.42125  1.000 35.90956  ? 52  THR B CB  1 
ATOM   2871 O  OG1 . THR C 1 72  ? -28.43976 -32.45608 13.45232  1.000 44.66919  ? 52  THR B OG1 1 
ATOM   2872 C  CG2 . THR C 1 72  ? -26.50498 -31.08766 13.85909  1.000 28.70873  ? 52  THR B CG2 1 
ATOM   2873 N  N   . THR C 1 73  ? -26.14478 -33.21651 17.13520  1.000 37.36554  ? 53  THR B N   1 
ATOM   2874 C  CA  . THR C 1 73  ? -25.26988 -33.02249 18.28545  1.000 35.20532  ? 53  THR B CA  1 
ATOM   2875 C  C   . THR C 1 73  ? -24.16566 -34.07030 18.31322  1.000 39.40548  ? 53  THR B C   1 
ATOM   2876 O  O   . THR C 1 73  ? -22.98097 -33.73741 18.44403  1.000 34.77234  ? 53  THR B O   1 
ATOM   2877 C  CB  . THR C 1 73  ? -26.08586 -33.06473 19.57905  1.000 38.26215  ? 53  THR B CB  1 
ATOM   2878 O  OG1 . THR C 1 73  ? -27.07163 -32.02405 19.55885  1.000 33.34454  ? 53  THR B OG1 1 
ATOM   2879 C  CG2 . THR C 1 73  ? -25.18164 -32.87719 20.78920  1.000 35.41577  ? 53  THR B CG2 1 
ATOM   2880 N  N   . GLU C 1 74  ? -24.53696 -35.34733 18.18488  1.000 40.10091  ? 54  GLU B N   1 
ATOM   2881 C  CA  . GLU C 1 74  ? -23.53221 -36.40463 18.23680  1.000 37.62832  ? 54  GLU B CA  1 
ATOM   2882 C  C   . GLU C 1 74  ? -22.55977 -36.29542 17.06955  1.000 41.70021  ? 54  GLU B C   1 
ATOM   2883 O  O   . GLU C 1 74  ? -21.36155 -36.55892 17.22276  1.000 41.12990  ? 54  GLU B O   1 
ATOM   2884 C  CB  . GLU C 1 74  ? -24.20205 -37.77751 18.24589  1.000 46.93516  ? 54  GLU B CB  1 
ATOM   2885 C  CG  . GLU C 1 74  ? -23.31783 -38.87539 18.81336  1.000 56.02208  ? 54  GLU B CG  1 
ATOM   2886 C  CD  . GLU C 1 74  ? -23.39135 -40.15901 18.01483  1.000 65.54231  ? 54  GLU B CD  1 
ATOM   2887 O  OE1 . GLU C 1 74  ? -24.16595 -40.20728 17.03646  1.000 72.90490  ? 54  GLU B OE1 1 
ATOM   2888 O  OE2 . GLU C 1 74  ? -22.67092 -41.11834 18.36299  1.000 69.60046  ? 54  GLU B OE2 1 
ATOM   2889 N  N   . HIS C 1 75  ? -23.05290 -35.89796 15.89553  1.000 41.54223  ? 55  HIS B N   1 
ATOM   2890 C  CA  . HIS C 1 75  ? -22.17205 -35.75415 14.74214  1.000 38.66646  ? 55  HIS B CA  1 
ATOM   2891 C  C   . HIS C 1 75  ? -21.16025 -34.63495 14.95660  1.000 44.63389  ? 55  HIS B C   1 
ATOM   2892 O  O   . HIS C 1 75  ? -19.96684 -34.80708 14.68268  1.000 45.27490  ? 55  HIS B O   1 
ATOM   2893 C  CB  . HIS C 1 75  ? -22.99586 -35.50144 13.48097  1.000 34.46112  ? 55  HIS B CB  1 
ATOM   2894 C  CG  . HIS C 1 75  ? -22.16691 -35.19602 12.27368  1.000 37.55991  ? 55  HIS B CG  1 
ATOM   2895 N  ND1 . HIS C 1 75  ? -21.17506 -36.03899 11.82053  1.000 35.79718  ? 55  HIS B ND1 1 
ATOM   2896 C  CD2 . HIS C 1 75  ? -22.17010 -34.13295 11.43499  1.000 41.80944  ? 55  HIS B CD2 1 
ATOM   2897 C  CE1 . HIS C 1 75  ? -20.60917 -35.51271 10.74913  1.000 42.02004  ? 55  HIS B CE1 1 
ATOM   2898 N  NE2 . HIS C 1 75  ? -21.19432 -34.35624 10.49407  1.000 51.41884  ? 55  HIS B NE2 1 
ATOM   2899 N  N   . ARG C 1 76  ? -21.61769 -33.47904 15.44998  1.000 30.07812  ? 56  ARG B N   1 
ATOM   2900 C  CA  . ARG C 1 76  ? -20.69874 -32.37313 15.70499  1.000 33.89095  ? 56  ARG B CA  1 
ATOM   2901 C  C   . ARG C 1 76  ? -19.70312 -32.72074 16.80631  1.000 36.31960  ? 56  ARG B C   1 
ATOM   2902 O  O   . ARG C 1 76  ? -18.53032 -32.33328 16.73477  1.000 36.48447  ? 56  ARG B O   1 
ATOM   2903 C  CB  . ARG C 1 76  ? -21.47631 -31.10744 16.07123  1.000 33.08480  ? 56  ARG B CB  1 
ATOM   2904 C  CG  . ARG C 1 76  ? -22.37574 -30.58069 14.96517  1.000 30.83286  ? 56  ARG B CG  1 
ATOM   2905 C  CD  . ARG C 1 76  ? -21.63895 -30.47260 13.63903  1.000 32.01141  ? 56  ARG B CD  1 
ATOM   2906 N  NE  . ARG C 1 76  ? -22.49547 -29.92112 12.59646  1.000 32.57305  ? 56  ARG B NE  1 
ATOM   2907 C  CZ  . ARG C 1 76  ? -22.18552 -29.88542 11.30778  1.000 42.67673  ? 56  ARG B CZ  1 
ATOM   2908 N  NH1 . ARG C 1 76  ? -21.05607 -30.40334 10.85281  1.000 36.39029  ? 56  ARG B NH1 1 
ATOM   2909 N  NH2 . ARG C 1 76  ? -23.03122 -29.31670 10.45355  1.000 41.33849  ? 56  ARG B NH2 1 
ATOM   2910 N  N   . VAL C 1 77  ? -20.14844 -33.45057 17.83208  1.000 33.23589  ? 57  VAL B N   1 
ATOM   2911 C  CA  . VAL C 1 77  ? -19.25489 -33.79805 18.93182  1.000 32.72904  ? 57  VAL B CA  1 
ATOM   2912 C  C   . VAL C 1 77  ? -18.18400 -34.77662 18.46427  1.000 38.45128  ? 57  VAL B C   1 
ATOM   2913 O  O   . VAL C 1 77  ? -16.99911 -34.61758 18.78378  1.000 31.39179  ? 57  VAL B O   1 
ATOM   2914 C  CB  . VAL C 1 77  ? -20.06476 -34.35105 20.11881  1.000 35.84396  ? 57  VAL B CB  1 
ATOM   2915 C  CG1 . VAL C 1 77  ? -19.14534 -34.98598 21.14358  1.000 33.51307  ? 57  VAL B CG1 1 
ATOM   2916 C  CG2 . VAL C 1 77  ? -20.87928 -33.23939 20.76088  1.000 30.68251  ? 57  VAL B CG2 1 
ATOM   2917 N  N   . ARG C 1 78  ? -18.57534 -35.79179 17.68756  1.000 43.53304  ? 58  ARG B N   1 
ATOM   2918 C  CA  . ARG C 1 78  ? -17.60263 -36.76990 17.20608  1.000 37.99574  ? 58  ARG B CA  1 
ATOM   2919 C  C   . ARG C 1 78  ? -16.56245 -36.11960 16.30172  1.000 35.20433  ? 58  ARG B C   1 
ATOM   2920 O  O   . ARG C 1 78  ? -15.38232 -36.49309 16.32544  1.000 42.26979  ? 58  ARG B O   1 
ATOM   2921 C  CB  . ARG C 1 78  ? -18.31585 -37.89946 16.46606  1.000 38.89360  ? 58  ARG B CB  1 
ATOM   2922 C  CG  . ARG C 1 78  ? -19.23804 -38.73642 17.32745  1.000 48.24828  ? 58  ARG B CG  1 
ATOM   2923 C  CD  . ARG C 1 78  ? -19.48997 -40.07990 16.65228  1.000 48.90810  ? 58  ARG B CD  1 
ATOM   2924 N  NE  . ARG C 1 78  ? -20.24485 -40.97639 17.51574  1.000 54.23806  ? 58  ARG B NE  1 
ATOM   2925 C  CZ  . ARG C 1 78  ? -19.70239 -41.70031 18.48300  1.000 61.59546  ? 58  ARG B CZ  1 
ATOM   2926 N  NH1 . ARG C 1 78  ? -18.40935 -41.62960 18.75099  1.000 54.76506  ? 58  ARG B NH1 1 
ATOM   2927 N  NH2 . ARG C 1 78  ? -20.47642 -42.51306 19.19863  1.000 60.57716  ? 58  ARG B NH2 1 
ATOM   2928 N  N   . SER C 1 79  ? -16.98061 -35.14095 15.50150  1.000 37.66417  ? 59  SER B N   1 
ATOM   2929 C  CA  . SER C 1 79  ? -16.06633 -34.42491 14.62375  1.000 44.04136  ? 59  SER B CA  1 
ATOM   2930 C  C   . SER C 1 79  ? -15.17542 -33.44077 15.37071  1.000 45.25547  ? 59  SER B C   1 
ATOM   2931 O  O   . SER C 1 79  ? -14.33123 -32.79413 14.74035  1.000 40.52354  ? 59  SER B O   1 
ATOM   2932 C  CB  . SER C 1 79  ? -16.85488 -33.69200 13.53703  1.000 45.03521  ? 59  SER B CB  1 
ATOM   2933 O  OG  . SER C 1 79  ? -17.62617 -34.59862 12.76686  1.000 52.79632  ? 59  SER B OG  1 
ATOM   2934 N  N   . GLY C 1 80  ? -15.34054 -33.30973 16.68508  1.000 42.25308  ? 60  GLY B N   1 
ATOM   2935 C  CA  . GLY C 1 80  ? -14.54787 -32.36433 17.44858  1.000 34.75230  ? 60  GLY B CA  1 
ATOM   2936 C  C   . GLY C 1 80  ? -14.84583 -30.91422 17.14303  1.000 34.41107  ? 60  GLY B C   1 
ATOM   2937 O  O   . GLY C 1 80  ? -13.95421 -30.06660 17.25863  1.000 39.95046  ? 60  GLY B O   1 
ATOM   2938 N  N   . SER C 1 81  ? -16.08195 -30.60151 16.76181  1.000 30.54784  ? 61  SER B N   1 
ATOM   2939 C  CA  . SER C 1 81  ? -16.45613 -29.25444 16.35555  1.000 30.96774  ? 61  SER B CA  1 
ATOM   2940 C  C   . SER C 1 81  ? -17.12399 -28.45075 17.46206  1.000 34.90047  ? 61  SER B C   1 
ATOM   2941 O  O   . SER C 1 81  ? -17.42308 -27.26982 17.25281  1.000 35.57526  ? 61  SER B O   1 
ATOM   2942 C  CB  . SER C 1 81  ? -17.38419 -29.30991 15.13842  1.000 32.54306  ? 61  SER B CB  1 
ATOM   2943 O  OG  . SER C 1 81  ? -16.74785 -29.94501 14.04255  1.000 39.20385  ? 61  SER B OG  1 
ATOM   2944 N  N   . VAL C 1 82  ? -17.36994 -29.04788 18.62224  1.000 26.82601  ? 62  VAL B N   1 
ATOM   2945 C  CA  . VAL C 1 82  ? -18.06198 -28.37416 19.71334  1.000 29.66195  ? 62  VAL B CA  1 
ATOM   2946 C  C   . VAL C 1 82  ? -17.01800 -27.93497 20.73205  1.000 36.28380  ? 62  VAL B C   1 
ATOM   2947 O  O   . VAL C 1 82  ? -16.36166 -28.76885 21.36704  1.000 35.56542  ? 62  VAL B O   1 
ATOM   2948 C  CB  . VAL C 1 82  ? -19.12248 -29.27887 20.35180  1.000 31.04929  ? 62  VAL B CB  1 
ATOM   2949 C  CG1 . VAL C 1 82  ? -19.96348 -28.48803 21.34269  1.000 22.58920  ? 62  VAL B CG1 1 
ATOM   2950 C  CG2 . VAL C 1 82  ? -19.99395 -29.90980 19.27655  1.000 27.99014  ? 62  VAL B CG2 1 
ATOM   2951 N  N   . HIS C 1 83  ? -16.86266 -26.62430 20.89223  1.000 27.43689  ? 63  HIS B N   1 
ATOM   2952 C  CA  . HIS C 1 83  ? -15.93373 -26.05887 21.85977  1.000 30.26635  ? 63  HIS B CA  1 
ATOM   2953 C  C   . HIS C 1 83  ? -16.72358 -25.55693 23.06018  1.000 33.53342  ? 63  HIS B C   1 
ATOM   2954 O  O   . HIS C 1 83  ? -17.65392 -24.75629 22.90351  1.000 32.68949  ? 63  HIS B O   1 
ATOM   2955 C  CB  . HIS C 1 83  ? -15.11919 -24.92471 21.23665  1.000 29.67174  ? 63  HIS B CB  1 
ATOM   2956 C  CG  . HIS C 1 83  ? -14.40460 -25.31484 19.97972  1.000 34.94384  ? 63  HIS B CG  1 
ATOM   2957 N  ND1 . HIS C 1 83  ? -13.03071 -25.40667 19.90148  1.000 29.41606  ? 63  HIS B ND1 1 
ATOM   2958 C  CD2 . HIS C 1 83  ? -14.87481 -25.64315 18.75260  1.000 30.98028  ? 63  HIS B CD2 1 
ATOM   2959 C  CE1 . HIS C 1 83  ? -12.68594 -25.77222 18.67976  1.000 32.87999  ? 63  HIS B CE1 1 
ATOM   2960 N  NE2 . HIS C 1 83  ? -13.78586 -25.92257 17.96325  1.000 33.55589  ? 63  HIS B NE2 1 
ATOM   2961 N  N   . LEU C 1 84  ? -16.36132 -26.03957 24.24931  1.000 33.16956  ? 64  LEU B N   1 
ATOM   2962 C  CA  . LEU C 1 84  ? -17.08760 -25.76091 25.47981  1.000 31.89474  ? 64  LEU B CA  1 
ATOM   2963 C  C   . LEU C 1 84  ? -16.19808 -24.99237 26.44816  1.000 31.57339  ? 64  LEU B C   1 
ATOM   2964 O  O   . LEU C 1 84  ? -15.04813 -25.38198 26.69333  1.000 29.24379  ? 64  LEU B O   1 
ATOM   2965 C  CB  . LEU C 1 84  ? -17.58153 -27.06159 26.12292  1.000 28.11433  ? 64  LEU B CB  1 
ATOM   2966 C  CG  . LEU C 1 84  ? -18.50412 -26.91699 27.33255  1.000 35.01677  ? 64  LEU B CG  1 
ATOM   2967 C  CD1 . LEU C 1 84  ? -19.67768 -27.87740 27.21857  1.000 32.86542  ? 64  LEU B CD1 1 
ATOM   2968 C  CD2 . LEU C 1 84  ? -17.74154 -27.15521 28.62860  1.000 33.88205  ? 64  LEU B CD2 1 
ATOM   2969 N  N   . LEU C 1 85  ? -16.74355 -23.90475 26.99220  1.000 36.02560  ? 65  LEU B N   1 
ATOM   2970 C  CA  . LEU C 1 85  ? -16.09737 -23.07573 27.99988  1.000 30.68303  ? 65  LEU B CA  1 
ATOM   2971 C  C   . LEU C 1 85  ? -16.66256 -23.44340 29.36361  1.000 34.66363  ? 65  LEU B C   1 
ATOM   2972 O  O   . LEU C 1 85  ? -17.86858 -23.27940 29.60420  1.000 34.78446  ? 65  LEU B O   1 
ATOM   2973 C  CB  . LEU C 1 85  ? -16.32876 -21.59138 27.71662  1.000 29.52995  ? 65  LEU B CB  1 
ATOM   2974 C  CG  . LEU C 1 85  ? -15.89078 -20.59366 28.79552  1.000 35.91101  ? 65  LEU B CG  1 
ATOM   2975 C  CD1 . LEU C 1 85  ? -14.37333 -20.56308 28.93950  1.000 29.72965  ? 65  LEU B CD1 1 
ATOM   2976 C  CD2 . LEU C 1 85  ? -16.43508 -19.20023 28.50116  1.000 34.80090  ? 65  LEU B CD2 1 
ATOM   2977 N  N   . ARG C 1 86  ? -15.78491 -23.90984 30.24953  1.000 29.90552  ? 66  ARG B N   1 
ATOM   2978 C  CA  . ARG C 1 86  ? -16.13270 -24.40051 31.57170  1.000 39.64957  ? 66  ARG B CA  1 
ATOM   2979 C  C   . ARG C 1 86  ? -15.60095 -23.44030 32.62988  1.000 40.31135  ? 66  ARG B C   1 
ATOM   2980 O  O   . ARG C 1 86  ? -14.49412 -22.89979 32.49746  1.000 41.76525  ? 66  ARG B O   1 
ATOM   2981 C  CB  . ARG C 1 86  ? -15.55257 -25.80537 31.78101  1.000 32.09968  ? 66  ARG B CB  1 
ATOM   2982 C  CG  . ARG C 1 86  ? -16.13530 -26.57937 32.94640  1.000 41.90719  ? 66  ARG B CG  1 
ATOM   2983 C  CD  . ARG C 1 86  ? -15.58537 -28.00184 32.98949  1.000 39.21515  ? 66  ARG B CD  1 
ATOM   2984 N  NE  . ARG C 1 86  ? -15.87817 -28.74192 31.76764  1.000 34.06033  ? 66  ARG B NE  1 
ATOM   2985 C  CZ  . ARG C 1 86  ? -16.96986 -29.47009 31.57838  1.000 37.03253  ? 66  ARG B CZ  1 
ATOM   2986 N  NH1 . ARG C 1 86  ? -17.89774 -29.58073 32.51505  1.000 32.10270  ? 66  ARG B NH1 1 
ATOM   2987 N  NH2 . ARG C 1 86  ? -17.13654 -30.10028 30.41934  1.000 34.10811  ? 66  ARG B NH2 1 
ATOM   2988 N  N   . HIS C 1 87  ? -16.39977 -23.22815 33.67551  1.000 40.51979  ? 67  HIS B N   1 
ATOM   2989 C  CA  . HIS C 1 87  ? -16.05196 -22.34311 34.78210  1.000 46.03474  ? 67  HIS B CA  1 
ATOM   2990 C  C   . HIS C 1 87  ? -16.35943 -23.05384 36.09060  1.000 43.39525  ? 67  HIS B C   1 
ATOM   2991 O  O   . HIS C 1 87  ? -17.52429 -23.35162 36.37627  1.000 45.49306  ? 67  HIS B O   1 
ATOM   2992 C  CB  . HIS C 1 87  ? -16.82052 -21.02125 34.69726  1.000 50.35389  ? 67  HIS B CB  1 
ATOM   2993 C  CG  . HIS C 1 87  ? -16.54599 -20.08595 35.83473  1.000 58.81541  ? 67  HIS B CG  1 
ATOM   2994 N  ND1 . HIS C 1 87  ? -15.31472 -19.49815 36.03519  1.000 61.52392  ? 67  HIS B ND1 1 
ATOM   2995 C  CD2 . HIS C 1 87  ? -17.34447 -19.63567 36.83177  1.000 55.66834  ? 67  HIS B CD2 1 
ATOM   2996 C  CE1 . HIS C 1 87  ? -15.36664 -18.72610 37.10594  1.000 63.34618  ? 67  HIS B CE1 1 
ATOM   2997 N  NE2 . HIS C 1 87  ? -16.58703 -18.79179 37.60769  1.000 62.29468  ? 67  HIS B NE2 1 
ATOM   2998 N  N   . ASP C 1 88  ? -15.31490 -23.32065 36.87931  1.000 43.05473  ? 68  ASP B N   1 
ATOM   2999 C  CA  . ASP C 1 88  ? -15.44254 -23.99576 38.17403  1.000 47.35283  ? 68  ASP B CA  1 
ATOM   3000 C  C   . ASP C 1 88  ? -16.11901 -25.35699 38.02632  1.000 54.13055  ? 68  ASP B C   1 
ATOM   3001 O  O   . ASP C 1 88  ? -16.91688 -25.77131 38.86955  1.000 54.77206  ? 68  ASP B O   1 
ATOM   3002 C  CB  . ASP C 1 88  ? -16.19241 -23.12359 39.18626  1.000 54.03914  ? 68  ASP B CB  1 
ATOM   3003 C  CG  . ASP C 1 88  ? -15.47561 -21.81799 39.48071  1.000 60.83329  ? 68  ASP B CG  1 
ATOM   3004 O  OD1 . ASP C 1 88  ? -14.22963 -21.79132 39.41845  1.000 61.07916  ? 68  ASP B OD1 1 
ATOM   3005 O  OD2 . ASP C 1 88  ? -16.16209 -20.81738 39.77482  1.000 71.76181  ? 68  ASP B OD2 1 
ATOM   3006 N  N   . GLY C 1 89  ? -15.80011 -26.05887 36.94023  1.000 55.45366  ? 69  GLY B N   1 
ATOM   3007 C  CA  . GLY C 1 89  ? -16.35353 -27.36514 36.67465  1.000 53.85535  ? 69  GLY B CA  1 
ATOM   3008 C  C   . GLY C 1 89  ? -17.67483 -27.37029 35.93537  1.000 45.19498  ? 69  GLY B C   1 
ATOM   3009 O  O   . GLY C 1 89  ? -17.99930 -28.37122 35.28690  1.000 49.55299  ? 69  GLY B O   1 
ATOM   3010 N  N   . ARG C 1 90  ? -18.44433 -26.28750 36.00898  1.000 38.73171  ? 70  ARG B N   1 
ATOM   3011 C  CA  . ARG C 1 90  ? -19.73301 -26.28593 35.32742  1.000 45.72994  ? 70  ARG B CA  1 
ATOM   3012 C  C   . ARG C 1 90  ? -19.59411 -25.70434 33.92290  1.000 36.16246  ? 70  ARG B C   1 
ATOM   3013 O  O   . ARG C 1 90  ? -18.80106 -24.78131 33.70770  1.000 41.31777  ? 70  ARG B O   1 
ATOM   3014 C  CB  . ARG C 1 90  ? -20.76166 -25.47404 36.11363  1.000 45.50506  ? 70  ARG B CB  1 
ATOM   3015 C  CG  . ARG C 1 90  ? -20.96684 -25.94685 37.54231  1.000 51.29513  ? 70  ARG B CG  1 
ATOM   3016 C  CD  . ARG C 1 90  ? -22.01024 -25.10754 38.27237  1.000 61.74684  ? 70  ARG B CD  1 
ATOM   3017 N  NE  . ARG C 1 90  ? -21.73097 -23.67773 38.19718  1.000 56.55039  ? 70  ARG B NE  1 
ATOM   3018 C  CZ  . ARG C 1 90  ? -20.76053 -23.06454 38.86191  1.000 60.66679  ? 70  ARG B CZ  1 
ATOM   3019 N  NH1 . ARG C 1 90  ? -19.92551 -23.73330 39.64060  1.000 60.58890  ? 70  ARG B NH1 1 
ATOM   3020 N  NH2 . ARG C 1 90  ? -20.62117 -21.74722 38.73825  1.000 60.54902  ? 70  ARG B NH2 1 
ATOM   3021 N  N   . PRO C 1 91  ? -20.34396 -26.23598 32.95790  1.000 38.84898  ? 71  PRO B N   1 
ATOM   3022 C  CA  . PRO C 1 91  ? -20.33683 -25.64656 31.61224  1.000 37.57467  ? 71  PRO B CA  1 
ATOM   3023 C  C   . PRO C 1 91  ? -20.94487 -24.25232 31.63674  1.000 36.01626  ? 71  PRO B C   1 
ATOM   3024 O  O   . PRO C 1 91  ? -22.06673 -24.05436 32.10661  1.000 42.73418  ? 71  PRO B O   1 
ATOM   3025 C  CB  . PRO C 1 91  ? -21.18911 -26.61887 30.78764  1.000 33.18609  ? 71  PRO B CB  1 
ATOM   3026 C  CG  . PRO C 1 91  ? -21.20235 -27.89033 31.57927  1.000 32.69473  ? 71  PRO B CG  1 
ATOM   3027 C  CD  . PRO C 1 91  ? -21.13451 -27.47557 33.01557  1.000 32.96059  ? 71  PRO B CD  1 
ATOM   3028 N  N   . ALA C 1 92  ? -20.18905 -23.28117 31.13715  1.000 33.03347  ? 72  ALA B N   1 
ATOM   3029 C  CA  . ALA C 1 92  ? -20.64155 -21.89766 31.10892  1.000 31.15642  ? 72  ALA B CA  1 
ATOM   3030 C  C   . ALA C 1 92  ? -21.06876 -21.44864 29.72059  1.000 27.19211  ? 72  ALA B C   1 
ATOM   3031 O  O   . ALA C 1 92  ? -22.02174 -20.67223 29.59189  1.000 25.27230  ? 72  ALA B O   1 
ATOM   3032 C  CB  . ALA C 1 92  ? -19.54500 -20.96534 31.63693  1.000 30.60007  ? 72  ALA B CB  1 
ATOM   3033 N  N   . GLY C 1 93  ? -20.37764 -21.90766 28.67957  1.000 28.43457  ? 73  GLY B N   1 
ATOM   3034 C  CA  . GLY C 1 93  ? -20.75477 -21.55010 27.32368  1.000 25.67469  ? 73  GLY B CA  1 
ATOM   3035 C  C   . GLY C 1 93  ? -20.23613 -22.58272 26.34837  1.000 32.46203  ? 73  GLY B C   1 
ATOM   3036 O  O   . GLY C 1 93  ? -19.53385 -23.52126 26.72764  1.000 31.68408  ? 73  GLY B O   1 
ATOM   3037 N  N   . MET C 1 94  ? -20.57805 -22.39147 25.07416  1.000 27.33942  ? 74  MET B N   1 
ATOM   3038 C  CA  . MET C 1 94  ? -20.06212 -23.25661 24.01803  1.000 30.05511  ? 74  MET B CA  1 
ATOM   3039 C  C   . MET C 1 94  ? -20.45942 -22.69560 22.65933  1.000 30.07017  ? 74  MET B C   1 
ATOM   3040 O  O   . MET C 1 94  ? -21.30411 -21.80135 22.54759  1.000 23.56333  ? 74  MET B O   1 
ATOM   3041 C  CB  . MET C 1 94  ? -20.57092 -24.69629 24.15017  1.000 31.03462  ? 74  MET B CB  1 
ATOM   3042 C  CG  . MET C 1 94  ? -22.01302 -24.87168 23.70881  1.000 35.37484  ? 74  MET B CG  1 
ATOM   3043 S  SD  . MET C 1 94  ? -22.48558 -26.60168 23.59275  1.000 30.83606  ? 74  MET B SD  1 
ATOM   3044 C  CE  . MET C 1 94  ? -24.26085 -26.43520 23.49936  1.000 23.73795  ? 74  MET B CE  1 
ATOM   3045 N  N   . PHE C 1 95  ? -19.84203 -23.26108 21.62344  1.000 24.20041  ? 75  PHE B N   1 
ATOM   3046 C  CA  . PHE C 1 95  ? -20.21517 -22.98692 20.24257  1.000 26.01272  ? 75  PHE B CA  1 
ATOM   3047 C  C   . PHE C 1 95  ? -19.81716 -24.18147 19.38748  1.000 32.24863  ? 75  PHE B C   1 
ATOM   3048 O  O   . PHE C 1 95  ? -19.05100 -25.04781 19.81883  1.000 31.30531  ? 75  PHE B O   1 
ATOM   3049 C  CB  . PHE C 1 95  ? -19.56459 -21.69502 19.71861  1.000 25.16138  ? 75  PHE B CB  1 
ATOM   3050 C  CG  . PHE C 1 95  ? -18.06340 -21.74708 19.65403  1.000 33.50081  ? 75  PHE B CG  1 
ATOM   3051 C  CD1 . PHE C 1 95  ? -17.41517 -22.18292 18.50607  1.000 28.01037  ? 75  PHE B CD1 1 
ATOM   3052 C  CD2 . PHE C 1 95  ? -17.29900 -21.35297 20.73878  1.000 35.53597  ? 75  PHE B CD2 1 
ATOM   3053 C  CE1 . PHE C 1 95  ? -16.03747 -22.23292 18.44773  1.000 33.47321  ? 75  PHE B CE1 1 
ATOM   3054 C  CE2 . PHE C 1 95  ? -15.91767 -21.39755 20.68525  1.000 37.10102  ? 75  PHE B CE2 1 
ATOM   3055 C  CZ  . PHE C 1 95  ? -15.28687 -21.84015 19.53892  1.000 32.71184  ? 75  PHE B CZ  1 
ATOM   3056 N  N   . THR C 1 96  ? -20.35225 -24.23009 18.16794  1.000 27.96642  ? 76  THR B N   1 
ATOM   3057 C  CA  . THR C 1 96  ? -19.99976 -25.25067 17.19367  1.000 27.97168  ? 76  THR B CA  1 
ATOM   3058 C  C   . THR C 1 96  ? -19.38142 -24.55638 15.99150  1.000 34.23744  ? 76  THR B C   1 
ATOM   3059 O  O   . THR C 1 96  ? -19.96623 -23.61462 15.44532  1.000 35.84678  ? 76  THR B O   1 
ATOM   3060 C  CB  . THR C 1 96  ? -21.22539 -26.07642 16.77935  1.000 30.77763  ? 76  THR B CB  1 
ATOM   3061 O  OG1 . THR C 1 96  ? -21.71382 -26.80951 17.90973  1.000 29.73117  ? 76  THR B OG1 1 
ATOM   3062 C  CG2 . THR C 1 96  ? -20.86791 -27.05322 15.66790  1.000 25.79311  ? 76  THR B CG2 1 
ATOM   3063 N  N   . LEU C 1 97  ? -18.19272 -25.00432 15.60029  1.000 30.33576  ? 77  LEU B N   1 
ATOM   3064 C  CA  . LEU C 1 97  ? -17.43632 -24.39718 14.51326  1.000 37.45484  ? 77  LEU B CA  1 
ATOM   3065 C  C   . LEU C 1 97  ? -17.15280 -25.47252 13.47657  1.000 35.98457  ? 77  LEU B C   1 
ATOM   3066 O  O   . LEU C 1 97  ? -16.43401 -26.43600 13.76334  1.000 39.19806  ? 77  LEU B O   1 
ATOM   3067 C  CB  . LEU C 1 97  ? -16.13571 -23.78184 15.03557  1.000 32.80698  ? 77  LEU B CB  1 
ATOM   3068 C  CG  . LEU C 1 97  ? -15.27832 -23.01490 14.03189  1.000 34.00055  ? 77  LEU B CG  1 
ATOM   3069 C  CD1 . LEU C 1 97  ? -16.01805 -21.78236 13.53977  1.000 31.95964  ? 77  LEU B CD1 1 
ATOM   3070 C  CD2 . LEU C 1 97  ? -13.94294 -22.63748 14.65163  1.000 33.22960  ? 77  LEU B CD2 1 
ATOM   3071 N  N   . THR C 1 98  ? -17.72281 -25.31898 12.28234  1.000 32.40271  ? 78  THR B N   1 
ATOM   3072 C  CA  . THR C 1 98  ? -17.62574 -26.35296 11.26061  1.000 35.59582  ? 78  THR B CA  1 
ATOM   3073 C  C   . THR C 1 98  ? -17.11216 -25.77020 9.95157   1.000 38.05972  ? 78  THR B C   1 
ATOM   3074 O  O   . THR C 1 98  ? -17.15915 -24.56227 9.71920   1.000 32.96417  ? 78  THR B O   1 
ATOM   3075 C  CB  . THR C 1 98  ? -18.97776 -27.04529 11.01495  1.000 29.03169  ? 78  THR B CB  1 
ATOM   3076 O  OG1 . THR C 1 98  ? -19.97250 -26.06776 10.68276  1.000 31.64984  ? 78  THR B OG1 1 
ATOM   3077 C  CG2 . THR C 1 98  ? -19.41559 -27.82336 12.24548  1.000 27.93811  ? 78  THR B CG2 1 
ATOM   3078 N  N   . TRP C 1 99  ? -16.60556 -26.65259 9.09287   1.000 39.18874  ? 79  TRP B N   1 
ATOM   3079 C  CA  . TRP C 1 99  ? -16.23096 -26.25307 7.74445   1.000 39.92773  ? 79  TRP B CA  1 
ATOM   3080 C  C   . TRP C 1 99  ? -17.37240 -26.41033 6.75219   1.000 42.71530  ? 79  TRP B C   1 
ATOM   3081 O  O   . TRP C 1 99  ? -17.32306 -25.81501 5.66993   1.000 47.32633  ? 79  TRP B O   1 
ATOM   3082 C  CB  . TRP C 1 99  ? -15.02010 -27.05653 7.26565   1.000 36.97211  ? 79  TRP B CB  1 
ATOM   3083 C  CG  . TRP C 1 99  ? -13.73283 -26.64503 7.90600   1.000 36.50827  ? 79  TRP B CG  1 
ATOM   3084 C  CD1 . TRP C 1 99  ? -13.19651 -27.13696 9.05957   1.000 36.85506  ? 79  TRP B CD1 1 
ATOM   3085 C  CD2 . TRP C 1 99  ? -12.81093 -25.66121 7.42150   1.000 37.82669  ? 79  TRP B CD2 1 
ATOM   3086 N  NE1 . TRP C 1 99  ? -11.99759 -26.51948 9.32432   1.000 41.22578  ? 79  TRP B NE1 1 
ATOM   3087 C  CE2 . TRP C 1 99  ? -11.73907 -25.60876 8.33388   1.000 31.27395  ? 79  TRP B CE2 1 
ATOM   3088 C  CE3 . TRP C 1 99  ? -12.78793 -24.82063 6.30428   1.000 39.36017  ? 79  TRP B CE3 1 
ATOM   3089 C  CZ2 . TRP C 1 99  ? -10.65660 -24.74982 8.16416   1.000 37.62949  ? 79  TRP B CZ2 1 
ATOM   3090 C  CZ3 . TRP C 1 99  ? -11.71303 -23.96860 6.13798   1.000 37.98118  ? 79  TRP B CZ3 1 
ATOM   3091 C  CH2 . TRP C 1 99  ? -10.66245 -23.93879 7.06296   1.000 42.83194  ? 79  TRP B CH2 1 
ATOM   3092 N  N   . ASP C 1 100 ? -18.39076 -27.19440 7.09330   1.000 40.47153  ? 80  ASP B N   1 
ATOM   3093 C  CA  . ASP C 1 100 ? -19.57880 -27.38247 6.28188   1.000 46.75928  ? 80  ASP B CA  1 
ATOM   3094 C  C   . ASP C 1 100 ? -20.71678 -26.50857 6.79671   1.000 43.00409  ? 80  ASP B C   1 
ATOM   3095 O  O   . ASP C 1 100 ? -20.79971 -26.23077 7.99714   1.000 42.86081  ? 80  ASP B O   1 
ATOM   3096 C  CB  . ASP C 1 100 ? -20.01973 -28.85111 6.29477   1.000 39.81501  ? 80  ASP B CB  1 
ATOM   3097 C  CG  . ASP C 1 100 ? -20.26471 -29.37683 7.69709   1.000 44.42136  ? 80  ASP B CG  1 
ATOM   3098 O  OD1 . ASP C 1 100 ? -19.38407 -29.19878 8.56465   1.000 45.53448  ? 80  ASP B OD1 1 
ATOM   3099 O  OD2 . ASP C 1 100 ? -21.34040 -29.96631 7.93178   1.000 46.93884  ? 80  ASP B OD2 1 
ATOM   3100 N  N   . PRO C 1 101 ? -21.60208 -26.05482 5.91370   1.000 46.06076  ? 81  PRO B N   1 
ATOM   3101 C  CA  . PRO C 1 101 ? -22.72470 -25.21289 6.34645   1.000 41.77056  ? 81  PRO B CA  1 
ATOM   3102 C  C   . PRO C 1 101 ? -23.69989 -26.00118 7.20129   1.000 42.83201  ? 81  PRO B C   1 
ATOM   3103 O  O   . PRO C 1 101 ? -24.22614 -27.03565 6.76494   1.000 47.25487  ? 81  PRO B O   1 
ATOM   3104 C  CB  . PRO C 1 101 ? -23.37518 -24.77630 5.02214   1.000 43.33207  ? 81  PRO B CB  1 
ATOM   3105 C  CG  . PRO C 1 101 ? -22.33912 -25.03688 3.96503   1.000 40.09238  ? 81  PRO B CG  1 
ATOM   3106 C  CD  . PRO C 1 101 ? -21.56885 -26.22203 4.45159   1.000 41.01285  ? 81  PRO B CD  1 
ATOM   3107 N  N   . PRO C 1 102 ? -23.96791 -25.54832 8.42839   1.000 41.95522  ? 82  PRO B N   1 
ATOM   3108 C  CA  . PRO C 1 102 ? -24.97825 -26.20617 9.26411   1.000 40.65583  ? 82  PRO B CA  1 
ATOM   3109 C  C   . PRO C 1 102 ? -26.40211 -25.76977 8.96530   1.000 39.03635  ? 82  PRO B C   1 
ATOM   3110 O  O   . PRO C 1 102 ? -27.32747 -26.23102 9.64270   1.000 41.62000  ? 82  PRO B O   1 
ATOM   3111 C  CB  . PRO C 1 102 ? -24.56529 -25.78161 10.67969  1.000 34.09199  ? 82  PRO B CB  1 
ATOM   3112 C  CG  . PRO C 1 102 ? -23.99858 -24.41760 10.48318  1.000 35.52284  ? 82  PRO B CG  1 
ATOM   3113 C  CD  . PRO C 1 102 ? -23.33260 -24.41616 9.12464   1.000 38.46943  ? 82  PRO B CD  1 
ATOM   3114 N  N   . PHE C 1 103 ? -26.59809 -24.89180 7.98512   1.000 41.80123  ? 83  PHE B N   1 
ATOM   3115 C  CA  . PHE C 1 103 ? -27.91725 -24.39397 7.63229   1.000 43.72913  ? 83  PHE B CA  1 
ATOM   3116 C  C   . PHE C 1 103 ? -28.01191 -24.27656 6.11958   1.000 50.26910  ? 83  PHE B C   1 
ATOM   3117 O  O   . PHE C 1 103 ? -27.00559 -24.29610 5.40884   1.000 47.76633  ? 83  PHE B O   1 
ATOM   3118 C  CB  . PHE C 1 103 ? -28.20831 -23.03381 8.28319   1.000 45.26897  ? 83  PHE B CB  1 
ATOM   3119 C  CG  . PHE C 1 103 ? -27.11879 -22.01601 8.07529   1.000 50.22004  ? 83  PHE B CG  1 
ATOM   3120 C  CD1 . PHE C 1 103 ? -27.08332 -21.23114 6.93082   1.000 44.59910  ? 83  PHE B CD1 1 
ATOM   3121 C  CD2 . PHE C 1 103 ? -26.13098 -21.84008 9.02973   1.000 47.29267  ? 83  PHE B CD2 1 
ATOM   3122 C  CE1 . PHE C 1 103 ? -26.08097 -20.29659 6.74462   1.000 47.12851  ? 83  PHE B CE1 1 
ATOM   3123 C  CE2 . PHE C 1 103 ? -25.13052 -20.90896 8.85043   1.000 45.64634  ? 83  PHE B CE2 1 
ATOM   3124 C  CZ  . PHE C 1 103 ? -25.10402 -20.13574 7.70773   1.000 51.58596  ? 83  PHE B CZ  1 
ATOM   3125 N  N   . ALA C 1 104 ? -29.23899 -24.15019 5.63145   1.000 53.94048  ? 84  ALA B N   1 
ATOM   3126 C  CA  . ALA C 1 104 ? -29.49307 -24.03108 4.20250   1.000 58.05212  ? 84  ALA B CA  1 
ATOM   3127 C  C   . ALA C 1 104 ? -29.58325 -22.55447 3.83571   1.000 47.12054  ? 84  ALA B C   1 
ATOM   3128 O  O   . ALA C 1 104 ? -30.37765 -21.81019 4.42263   1.000 55.29948  ? 84  ALA B O   1 
ATOM   3129 C  CB  . ALA C 1 104 ? -30.77503 -24.76749 3.81408   1.000 54.25349  ? 84  ALA B CB  1 
ATOM   3130 N  N   . ALA C 1 105 ? -28.75770 -22.13107 2.88032   1.000 50.77441  ? 85  ALA B N   1 
ATOM   3131 C  CA  . ALA C 1 105 ? -28.75822 -20.75141 2.41289   1.000 55.94129  ? 85  ALA B CA  1 
ATOM   3132 C  C   . ALA C 1 105 ? -28.43190 -20.73254 0.92842   1.000 64.20920  ? 85  ALA B C   1 
ATOM   3133 O  O   . ALA C 1 105 ? -27.48727 -21.39753 0.49322   1.000 63.52709  ? 85  ALA B O   1 
ATOM   3134 C  CB  . ALA C 1 105 ? -27.74994 -19.89898 3.19054   1.000 48.35210  ? 85  ALA B CB  1 
ATOM   3135 N  N   . ASP C 1 106 ? -29.21197 -19.97390 0.16073   1.000 63.86420  ? 86  ASP B N   1 
ATOM   3136 C  CA  . ASP C 1 106 ? -28.95957 -19.85404 -1.26804  1.000 70.43060  ? 86  ASP B CA  1 
ATOM   3137 C  C   . ASP C 1 106 ? -27.59391 -19.22283 -1.51191  1.000 74.41016  ? 86  ASP B C   1 
ATOM   3138 O  O   . ASP C 1 106 ? -27.06856 -18.48133 -0.67647  1.000 67.09613  ? 86  ASP B O   1 
ATOM   3139 C  CB  . ASP C 1 106 ? -30.05131 -19.01725 -1.93821  1.000 61.57679  ? 86  ASP B CB  1 
ATOM   3140 C  CG  . ASP C 1 106 ? -31.44125 -19.57833 -1.70959  1.000 60.81685  ? 86  ASP B CG  1 
ATOM   3141 O  OD1 . ASP C 1 106 ? -31.55200 -20.76742 -1.34477  1.000 64.24113  ? 86  ASP B OD1 1 
ATOM   3142 O  OD2 . ASP C 1 106 ? -32.42424 -18.83055 -1.89973  1.000 57.73484  ? 86  ASP B OD2 1 
ATOM   3143 N  N   . GLU C 1 107 ? -27.01236 -19.53095 -2.66802  1.000 69.23126  ? 87  GLU B N   1 
ATOM   3144 C  CA  . GLU C 1 107 ? -25.71837 -18.96229 -3.01348  1.000 75.78719  ? 87  GLU B CA  1 
ATOM   3145 C  C   . GLU C 1 107 ? -25.84533 -17.45563 -3.20006  1.000 71.53060  ? 87  GLU B C   1 
ATOM   3146 O  O   . GLU C 1 107 ? -26.86108 -16.95553 -3.69192  1.000 76.82623  ? 87  GLU B O   1 
ATOM   3147 C  CB  . GLU C 1 107 ? -25.15875 -19.62093 -4.27604  1.000 83.93547  ? 87  GLU B CB  1 
ATOM   3148 C  CG  . GLU C 1 107 ? -25.96616 -19.38936 -5.54076  1.000 84.67848  ? 87  GLU B CG  1 
ATOM   3149 C  CD  . GLU C 1 107 ? -25.42831 -20.18006 -6.71895  1.000 85.06658  ? 87  GLU B CD  1 
ATOM   3150 O  OE1 . GLU C 1 107 ? -25.17421 -21.39232 -6.55537  1.000 77.59115  ? 87  GLU B OE1 1 
ATOM   3151 O  OE2 . GLU C 1 107 ? -25.24901 -19.58829 -7.80437  1.000 83.15116  ? 87  GLU B OE2 1 
ATOM   3152 N  N   . GLY C 1 108 ? -24.81203 -16.72922 -2.78351  1.000 65.12987  ? 88  GLY B N   1 
ATOM   3153 C  CA  . GLY C 1 108 ? -24.85344 -15.28451 -2.77339  1.000 59.35811  ? 88  GLY B CA  1 
ATOM   3154 C  C   . GLY C 1 108 ? -25.32689 -14.66863 -1.47517  1.000 64.64159  ? 88  GLY B C   1 
ATOM   3155 O  O   . GLY C 1 108 ? -25.35056 -13.43519 -1.36693  1.000 69.58886  ? 88  GLY B O   1 
ATOM   3156 N  N   . ALA C 1 109 ? -25.71392 -15.48343 -0.49002  1.000 59.36754  ? 89  ALA B N   1 
ATOM   3157 C  CA  . ALA C 1 109 ? -26.10132 -14.95476 0.81185   1.000 54.42550  ? 89  ALA B CA  1 
ATOM   3158 C  C   . ALA C 1 109 ? -24.90453 -14.46357 1.61194   1.000 54.02543  ? 89  ALA B C   1 
ATOM   3159 O  O   . ALA C 1 109 ? -25.08225 -13.67936 2.55000   1.000 52.62673  ? 89  ALA B O   1 
ATOM   3160 C  CB  . ALA C 1 109 ? -26.85681 -16.01681 1.61212   1.000 52.09538  ? 89  ALA B CB  1 
ATOM   3161 N  N   . PHE C 1 110 ? -23.70226 -14.91355 1.26971   1.000 56.41881  ? 90  PHE B N   1 
ATOM   3162 C  CA  . PHE C 1 110 ? -22.47201 -14.49260 1.91384   1.000 50.95844  ? 90  PHE B CA  1 
ATOM   3163 C  C   . PHE C 1 110 ? -21.49391 -13.97327 0.86911   1.000 54.20700  ? 90  PHE B C   1 
ATOM   3164 O  O   . PHE C 1 110 ? -21.55610 -14.36803 -0.29804  1.000 54.01494  ? 90  PHE B O   1 
ATOM   3165 C  CB  . PHE C 1 110 ? -21.82191 -15.65183 2.68354   1.000 46.45832  ? 90  PHE B CB  1 
ATOM   3166 C  CG  . PHE C 1 110 ? -22.68553 -16.22393 3.77104   1.000 54.30504  ? 90  PHE B CG  1 
ATOM   3167 C  CD1 . PHE C 1 110 ? -22.81963 -15.57070 4.98692   1.000 42.74255  ? 90  PHE B CD1 1 
ATOM   3168 C  CD2 . PHE C 1 110 ? -23.35318 -17.42177 3.58168   1.000 41.65482  ? 90  PHE B CD2 1 
ATOM   3169 C  CE1 . PHE C 1 110 ? -23.61182 -16.09921 5.98816   1.000 45.10023  ? 90  PHE B CE1 1 
ATOM   3170 C  CE2 . PHE C 1 110 ? -24.14560 -17.95625 4.57846   1.000 36.73735  ? 90  PHE B CE2 1 
ATOM   3171 C  CZ  . PHE C 1 110 ? -24.27583 -17.29570 5.78300   1.000 51.44837  ? 90  PHE B CZ  1 
ATOM   3172 N  N   . PRO C 1 111 ? -20.58609 -13.07824 1.26546   1.000 48.38789  ? 91  PRO B N   1 
ATOM   3173 C  CA  . PRO C 1 111 ? -19.53593 -12.66803 0.34071   1.000 43.78334  ? 91  PRO B CA  1 
ATOM   3174 C  C   . PRO C 1 111 ? -18.64650 -13.84870 -0.00668  1.000 49.30828  ? 91  PRO B C   1 
ATOM   3175 O  O   . PRO C 1 111 ? -18.53672 -14.81055 0.77053   1.000 51.11874  ? 91  PRO B O   1 
ATOM   3176 C  CB  . PRO C 1 111 ? -18.76803 -11.60230 1.14122   1.000 51.98315  ? 91  PRO B CB  1 
ATOM   3177 C  CG  . PRO C 1 111 ? -19.72549 -11.13170 2.18024   1.000 50.99948  ? 91  PRO B CG  1 
ATOM   3178 C  CD  . PRO C 1 111 ? -20.55433 -12.32441 2.52542   1.000 51.15710  ? 91  PRO B CD  1 
ATOM   3179 N  N   . PRO C 1 112 ? -18.01331 -13.81481 -1.17645  1.000 52.64036  ? 92  PRO B N   1 
ATOM   3180 C  CA  . PRO C 1 112 ? -17.11555 -14.91851 -1.55002  1.000 52.46752  ? 92  PRO B CA  1 
ATOM   3181 C  C   . PRO C 1 112 ? -15.97468 -15.06556 -0.55396  1.000 43.23585  ? 92  PRO B C   1 
ATOM   3182 O  O   . PRO C 1 112 ? -15.44490 -14.08060 -0.03457  1.000 51.07977  ? 92  PRO B O   1 
ATOM   3183 C  CB  . PRO C 1 112 ? -16.60556 -14.50550 -2.93648  1.000 48.75805  ? 92  PRO B CB  1 
ATOM   3184 C  CG  . PRO C 1 112 ? -17.64442 -13.55553 -3.45598  1.000 44.33328  ? 92  PRO B CG  1 
ATOM   3185 C  CD  . PRO C 1 112 ? -18.15956 -12.82518 -2.25357  1.000 47.93466  ? 92  PRO B CD  1 
ATOM   3186 N  N   . ALA C 1 113 ? -15.60407 -16.31655 -0.28799  1.000 46.07411  ? 93  ALA B N   1 
ATOM   3187 C  CA  . ALA C 1 113 ? -14.55682 -16.62533 0.67237   1.000 49.44108  ? 93  ALA B CA  1 
ATOM   3188 C  C   . ALA C 1 113 ? -13.79421 -17.85475 0.20306   1.000 47.25090  ? 93  ALA B C   1 
ATOM   3189 O  O   . ALA C 1 113 ? -14.36577 -18.77545 -0.38820  1.000 54.08417  ? 93  ALA B O   1 
ATOM   3190 C  CB  . ALA C 1 113 ? -15.12399 -16.85534 2.08009   1.000 41.68079  ? 93  ALA B CB  1 
ATOM   3191 N  N   . GLU C 1 114 ? -12.49161 -17.85550 0.47919   1.000 51.41237  ? 94  GLU B N   1 
ATOM   3192 C  CA  . GLU C 1 114 ? -11.62996 -18.95677 0.06992   1.000 48.61354  ? 94  GLU B CA  1 
ATOM   3193 C  C   . GLU C 1 114 ? -11.74726 -20.13864 1.02747   1.000 54.01222  ? 94  GLU B C   1 
ATOM   3194 O  O   . GLU C 1 114 ? -11.88289 -21.29035 0.59579   1.000 53.83630  ? 94  GLU B O   1 
ATOM   3195 C  CB  . GLU C 1 114 ? -10.18550 -18.45984 -0.01746  1.000 55.29380  ? 94  GLU B CB  1 
ATOM   3196 C  CG  . GLU C 1 114 ? -9.95292  -17.45111 -1.12832  1.000 67.61260  ? 94  GLU B CG  1 
ATOM   3197 C  CD  . GLU C 1 114 ? -9.36905  -18.08622 -2.36903  1.000 78.59080  ? 94  GLU B CD  1 
ATOM   3198 O  OE1 . GLU C 1 114 ? -8.33927  -18.78319 -2.25025  1.000 83.01684  ? 94  GLU B OE1 1 
ATOM   3199 O  OE2 . GLU C 1 114 ? -9.95249  -17.90724 -3.45863  1.000 79.07676  ? 94  GLU B OE2 1 
ATOM   3200 N  N   . ARG C 1 115 ? -11.70215 -19.86714 2.33025   1.000 49.21643  ? 95  ARG B N   1 
ATOM   3201 C  CA  . ARG C 1 115 ? -11.78503 -20.90042 3.36311   1.000 44.49789  ? 95  ARG B CA  1 
ATOM   3202 C  C   . ARG C 1 115 ? -12.70173 -20.41264 4.47371   1.000 48.18526  ? 95  ARG B C   1 
ATOM   3203 O  O   . ARG C 1 115 ? -12.24397 -19.99649 5.54635   1.000 44.70439  ? 95  ARG B O   1 
ATOM   3204 C  CB  . ARG C 1 115 ? -10.39683 -21.24340 3.90754   1.000 53.86915  ? 95  ARG B CB  1 
ATOM   3205 C  CG  . ARG C 1 115 ? -9.45697  -21.84665 2.87852   1.000 53.72268  ? 95  ARG B CG  1 
ATOM   3206 C  CD  . ARG C 1 115 ? -8.03396  -21.91247 3.40099   1.000 56.95483  ? 95  ARG B CD  1 
ATOM   3207 N  NE  . ARG C 1 115 ? -7.13914  -21.03675 2.65353   1.000 65.31639  ? 95  ARG B NE  1 
ATOM   3208 C  CZ  . ARG C 1 115 ? -6.88468  -19.77441 2.97032   1.000 69.06564  ? 95  ARG B CZ  1 
ATOM   3209 N  NH1 . ARG C 1 115 ? -7.43891  -19.20075 4.02616   1.000 71.17435  ? 95  ARG B NH1 1 
ATOM   3210 N  NH2 . ARG C 1 115 ? -6.05357  -19.06954 2.20796   1.000 66.27776  ? 95  ARG B NH2 1 
ATOM   3211 N  N   . PRO C 1 116 ? -14.01257 -20.43247 4.24556   1.000 47.78626  ? 96  PRO B N   1 
ATOM   3212 C  CA  . PRO C 1 116 ? -14.94391 -19.96484 5.27297   1.000 43.04325  ? 96  PRO B CA  1 
ATOM   3213 C  C   . PRO C 1 116 ? -15.26531 -21.05081 6.28424   1.000 40.66045  ? 96  PRO B C   1 
ATOM   3214 O  O   . PRO C 1 116 ? -15.32732 -22.23935 5.96219   1.000 43.35391  ? 96  PRO B O   1 
ATOM   3215 C  CB  . PRO C 1 116 ? -16.18970 -19.58991 4.46511   1.000 44.11663  ? 96  PRO B CB  1 
ATOM   3216 C  CG  . PRO C 1 116 ? -16.17027 -20.55028 3.32300   1.000 40.26617  ? 96  PRO B CG  1 
ATOM   3217 C  CD  . PRO C 1 116 ? -14.71213 -20.81637 3.00491   1.000 48.15252  ? 96  PRO B CD  1 
ATOM   3218 N  N   . LEU C 1 117 ? -15.45950 -20.62263 7.52789   1.000 46.53989  ? 97  LEU B N   1 
ATOM   3219 C  CA  . LEU C 1 117 ? -15.97848 -21.48486 8.57696   1.000 38.03004  ? 97  LEU B CA  1 
ATOM   3220 C  C   . LEU C 1 117 ? -17.33938 -20.97827 9.02949   1.000 33.54704  ? 97  LEU B C   1 
ATOM   3221 O  O   . LEU C 1 117 ? -17.69682 -19.81560 8.82321   1.000 39.00462  ? 97  LEU B O   1 
ATOM   3222 C  CB  . LEU C 1 117 ? -15.02499 -21.56809 9.77201   1.000 41.53480  ? 97  LEU B CB  1 
ATOM   3223 C  CG  . LEU C 1 117 ? -13.74356 -22.35981 9.52789   1.000 36.48386  ? 97  LEU B CG  1 
ATOM   3224 C  CD1 . LEU C 1 117 ? -12.62131 -21.41288 9.20434   1.000 33.97682  ? 97  LEU B CD1 1 
ATOM   3225 C  CD2 . LEU C 1 117 ? -13.39637 -23.22452 10.73014  1.000 40.53459  ? 97  LEU B CD2 1 
ATOM   3226 N  N   . TYR C 1 118 ? -18.09582 -21.87087 9.65850   1.000 29.74277  ? 98  TYR B N   1 
ATOM   3227 C  CA  . TYR C 1 118 ? -19.47654 -21.61708 10.03233  1.000 35.06948  ? 98  TYR B CA  1 
ATOM   3228 C  C   . TYR C 1 118 ? -19.63064 -21.75874 11.53813  1.000 33.91798  ? 98  TYR B C   1 
ATOM   3229 O  O   . TYR C 1 118 ? -19.20419 -22.76455 12.12218  1.000 36.07994  ? 98  TYR B O   1 
ATOM   3230 C  CB  . TYR C 1 118 ? -20.41897 -22.58033 9.30806   1.000 33.67614  ? 98  TYR B CB  1 
ATOM   3231 C  CG  . TYR C 1 118 ? -20.43323 -22.40481 7.80721   1.000 36.01479  ? 98  TYR B CG  1 
ATOM   3232 C  CD1 . TYR C 1 118 ? -19.47092 -23.00949 7.00902   1.000 36.57657  ? 98  TYR B CD1 1 
ATOM   3233 C  CD2 . TYR C 1 118 ? -21.41004 -21.63651 7.18746   1.000 44.32866  ? 98  TYR B CD2 1 
ATOM   3234 C  CE1 . TYR C 1 118 ? -19.47962 -22.85344 5.63878   1.000 38.72835  ? 98  TYR B CE1 1 
ATOM   3235 C  CE2 . TYR C 1 118 ? -21.42770 -21.47451 5.81381   1.000 37.69354  ? 98  TYR B CE2 1 
ATOM   3236 C  CZ  . TYR C 1 118 ? -20.45879 -22.08689 5.04564   1.000 36.05063  ? 98  TYR B CZ  1 
ATOM   3237 O  OH  . TYR C 1 118 ? -20.46172 -21.93575 3.67890   1.000 44.75780  ? 98  TYR B OH  1 
ATOM   3238 N  N   . LEU C 1 119 ? -20.23224 -20.74450 12.15256  1.000 29.02178  ? 99  LEU B N   1 
ATOM   3239 C  CA  . LEU C 1 119 ? -20.54765 -20.72806 13.57342  1.000 32.80365  ? 99  LEU B CA  1 
ATOM   3240 C  C   . LEU C 1 119 ? -22.01377 -21.08762 13.76803  1.000 35.43423  ? 99  LEU B C   1 
ATOM   3241 O  O   . LEU C 1 119 ? -22.89188 -20.49083 13.13568  1.000 37.82662  ? 99  LEU B O   1 
ATOM   3242 C  CB  . LEU C 1 119 ? -20.26663 -19.34803 14.17071  1.000 33.63154  ? 99  LEU B CB  1 
ATOM   3243 C  CG  . LEU C 1 119 ? -20.81887 -19.07107 15.56995  1.000 31.76184  ? 99  LEU B CG  1 
ATOM   3244 C  CD1 . LEU C 1 119 ? -19.99701 -19.78356 16.62617  1.000 24.23146  ? 99  LEU B CD1 1 
ATOM   3245 C  CD2 . LEU C 1 119 ? -20.87120 -17.57618 15.84118  1.000 38.10641  ? 99  LEU B CD2 1 
ATOM   3246 N  N   . SER C 1 120 ? -22.27764 -22.05193 14.64599  1.000 30.10631  ? 100 SER B N   1 
ATOM   3247 C  CA  . SER C 1 120 ? -23.64228 -22.44554 14.95570  1.000 27.72019  ? 100 SER B CA  1 
ATOM   3248 C  C   . SER C 1 120 ? -23.74254 -22.80383 16.43072  1.000 31.05008  ? 100 SER B C   1 
ATOM   3249 O  O   . SER C 1 120 ? -22.73729 -22.93668 17.13628  1.000 28.85733  ? 100 SER B O   1 
ATOM   3250 C  CB  . SER C 1 120 ? -24.10456 -23.62436 14.08402  1.000 21.82454  ? 100 SER B CB  1 
ATOM   3251 O  OG  . SER C 1 120 ? -23.32203 -24.78037 14.32440  1.000 25.66878  ? 100 SER B OG  1 
ATOM   3252 N  N   . ARG C 1 121 ? -24.98554 -22.93168 16.89337  1.000 26.54864  ? 101 ARG B N   1 
ATOM   3253 C  CA  . ARG C 1 121 ? -25.28340 -23.47145 18.21731  1.000 26.16019  ? 101 ARG B CA  1 
ATOM   3254 C  C   . ARG C 1 121 ? -24.52665 -22.72946 19.31468  1.000 29.06518  ? 101 ARG B C   1 
ATOM   3255 O  O   . ARG C 1 121 ? -23.96264 -23.33469 20.23007  1.000 27.99333  ? 101 ARG B O   1 
ATOM   3256 C  CB  . ARG C 1 121 ? -24.98169 -24.96785 18.26627  1.000 33.71939  ? 101 ARG B CB  1 
ATOM   3257 C  CG  . ARG C 1 121 ? -25.82984 -25.79457 17.31667  1.000 28.64744  ? 101 ARG B CG  1 
ATOM   3258 C  CD  . ARG C 1 121 ? -25.61261 -27.27159 17.55199  1.000 28.31169  ? 101 ARG B CD  1 
ATOM   3259 N  NE  . ARG C 1 121 ? -26.79813 -28.05675 17.23738  1.000 34.77994  ? 101 ARG B NE  1 
ATOM   3260 C  CZ  . ARG C 1 121 ? -27.00118 -29.29604 17.66091  1.000 36.14711  ? 101 ARG B CZ  1 
ATOM   3261 N  NH1 . ARG C 1 121 ? -26.11214 -29.92046 18.41391  1.000 33.70584  ? 101 ARG B NH1 1 
ATOM   3262 N  NH2 . ARG C 1 121 ? -28.12990 -29.91901 17.33206  1.000 37.33190  ? 101 ARG B NH2 1 
ATOM   3263 N  N   . LEU C 1 122 ? -24.49327 -21.40481 19.20610  1.000 30.49651  ? 102 LEU B N   1 
ATOM   3264 C  CA  . LEU C 1 122 ? -23.97985 -20.58457 20.29163  1.000 31.01190  ? 102 LEU B CA  1 
ATOM   3265 C  C   . LEU C 1 122 ? -24.88900 -20.73324 21.50454  1.000 29.07748  ? 102 LEU B C   1 
ATOM   3266 O  O   . LEU C 1 122 ? -26.10726 -20.56046 21.40448  1.000 40.23003  ? 102 LEU B O   1 
ATOM   3267 C  CB  . LEU C 1 122 ? -23.89366 -19.12183 19.86032  1.000 30.56167  ? 102 LEU B CB  1 
ATOM   3268 C  CG  . LEU C 1 122 ? -23.31264 -18.14229 20.88479  1.000 34.66158  ? 102 LEU B CG  1 
ATOM   3269 C  CD1 . LEU C 1 122 ? -21.79661 -18.27707 20.97565  1.000 38.88315  ? 102 LEU B CD1 1 
ATOM   3270 C  CD2 . LEU C 1 122 ? -23.71749 -16.71921 20.54639  1.000 32.36876  ? 102 LEU B CD2 1 
ATOM   3271 N  N   . ALA C 1 123 ? -24.30345 -21.07206 22.64981  1.000 26.82309  ? 103 ALA B N   1 
ATOM   3272 C  CA  . ALA C 1 123 ? -25.08800 -21.33378 23.84648  1.000 29.56578  ? 103 ALA B CA  1 
ATOM   3273 C  C   . ALA C 1 123 ? -24.36775 -20.79522 25.07100  1.000 28.75103  ? 103 ALA B C   1 
ATOM   3274 O  O   . ALA C 1 123 ? -23.15293 -20.95929 25.21211  1.000 32.63511  ? 103 ALA B O   1 
ATOM   3275 C  CB  . ALA C 1 123 ? -25.35856 -22.83463 24.01689  1.000 27.20697  ? 103 ALA B CB  1 
ATOM   3276 N  N   . VAL C 1 124 ? -25.12825 -20.15794 25.95401  1.000 23.80930  ? 104 VAL B N   1 
ATOM   3277 C  CA  . VAL C 1 124 ? -24.63220 -19.67323 27.23450  1.000 34.32924  ? 104 VAL B CA  1 
ATOM   3278 C  C   . VAL C 1 124 ? -25.47841 -20.30701 28.32888  1.000 33.20023  ? 104 VAL B C   1 
ATOM   3279 O  O   . VAL C 1 124 ? -26.71066 -20.32990 28.22842  1.000 41.68886  ? 104 VAL B O   1 
ATOM   3280 C  CB  . VAL C 1 124 ? -24.67906 -18.13536 27.31592  1.000 31.11199  ? 104 VAL B CB  1 
ATOM   3281 C  CG1 . VAL C 1 124 ? -24.44796 -17.66609 28.74183  1.000 32.47849  ? 104 VAL B CG1 1 
ATOM   3282 C  CG2 . VAL C 1 124 ? -23.64441 -17.52309 26.38172  1.000 32.69907  ? 104 VAL B CG2 1 
ATOM   3283 N  N   . ALA C 1 125 ? -24.82033 -20.83765 29.35478  1.000 30.94539  ? 105 ALA B N   1 
ATOM   3284 C  CA  . ALA C 1 125 ? -25.54630 -21.42188 30.47144  1.000 30.95761  ? 105 ALA B CA  1 
ATOM   3285 C  C   . ALA C 1 125 ? -26.48713 -20.38213 31.07510  1.000 31.28910  ? 105 ALA B C   1 
ATOM   3286 O  O   . ALA C 1 125 ? -26.12960 -19.20124 31.16413  1.000 36.89212  ? 105 ALA B O   1 
ATOM   3287 C  CB  . ALA C 1 125 ? -24.57946 -21.93783 31.53823  1.000 30.70372  ? 105 ALA B CB  1 
ATOM   3288 N  N   . PRO C 1 126 ? -27.69424 -20.77995 31.48505  1.000 33.54395  ? 106 PRO B N   1 
ATOM   3289 C  CA  . PRO C 1 126 ? -28.66054 -19.80019 32.01434  1.000 39.30118  ? 106 PRO B CA  1 
ATOM   3290 C  C   . PRO C 1 126 ? -28.12999 -18.96252 33.16568  1.000 38.09248  ? 106 PRO B C   1 
ATOM   3291 O  O   . PRO C 1 126 ? -28.55518 -17.81104 33.32751  1.000 31.02425  ? 106 PRO B O   1 
ATOM   3292 C  CB  . PRO C 1 126 ? -29.83377 -20.68357 32.45864  1.000 36.33766  ? 106 PRO B CB  1 
ATOM   3293 C  CG  . PRO C 1 126 ? -29.73092 -21.90136 31.60007  1.000 39.73909  ? 106 PRO B CG  1 
ATOM   3294 C  CD  . PRO C 1 126 ? -28.26426 -22.13596 31.39786  1.000 33.73978  ? 106 PRO B CD  1 
ATOM   3295 N  N   . GLU C 1 127 ? -27.20944 -19.50362 33.96914  1.000 40.88329  ? 107 GLU B N   1 
ATOM   3296 C  CA  . GLU C 1 127 ? -26.61605 -18.72572 35.05203  1.000 40.74602  ? 107 GLU B CA  1 
ATOM   3297 C  C   . GLU C 1 127 ? -25.89914 -17.48611 34.53131  1.000 47.40069  ? 107 GLU B C   1 
ATOM   3298 O  O   . GLU C 1 127 ? -25.81329 -16.47518 35.23851  1.000 47.40579  ? 107 GLU B O   1 
ATOM   3299 C  CB  . GLU C 1 127 ? -25.64740 -19.59948 35.84940  1.000 48.78080  ? 107 GLU B CB  1 
ATOM   3300 C  CG  . GLU C 1 127 ? -25.00364 -18.89980 37.03863  1.000 54.49569  ? 107 GLU B CG  1 
ATOM   3301 C  CD  . GLU C 1 127 ? -23.94580 -19.74956 37.71026  1.000 57.85121  ? 107 GLU B CD  1 
ATOM   3302 O  OE1 . GLU C 1 127 ? -23.63207 -20.83681 37.18037  1.000 57.10732  ? 107 GLU B OE1 1 
ATOM   3303 O  OE2 . GLU C 1 127 ? -23.42911 -19.32967 38.76728  1.000 62.21696  ? 107 GLU B OE2 1 
ATOM   3304 N  N   . TRP C 1 128 ? -25.39427 -17.53498 33.29984  1.000 47.03978  ? 108 TRP B N   1 
ATOM   3305 C  CA  . TRP C 1 128 ? -24.57208 -16.46605 32.75464  1.000 38.40492  ? 108 TRP B CA  1 
ATOM   3306 C  C   . TRP C 1 128 ? -25.29649 -15.60604 31.72964  1.000 42.89326  ? 108 TRP B C   1 
ATOM   3307 O  O   . TRP C 1 128 ? -24.66954 -14.72395 31.13261  1.000 43.70678  ? 108 TRP B O   1 
ATOM   3308 C  CB  . TRP C 1 128 ? -23.30320 -17.05453 32.13217  1.000 37.37610  ? 108 TRP B CB  1 
ATOM   3309 C  CG  . TRP C 1 128 ? -22.57585 -17.97623 33.05560  1.000 46.33244  ? 108 TRP B CG  1 
ATOM   3310 C  CD1 . TRP C 1 128 ? -22.51659 -19.33731 32.97706  1.000 44.39787  ? 108 TRP B CD1 1 
ATOM   3311 C  CD2 . TRP C 1 128 ? -21.81556 -17.60709 34.21147  1.000 48.65419  ? 108 TRP B CD2 1 
ATOM   3312 N  NE1 . TRP C 1 128 ? -21.75884 -19.83794 34.00775  1.000 53.92550  ? 108 TRP B NE1 1 
ATOM   3313 C  CE2 . TRP C 1 128 ? -21.31746 -18.79586 34.78031  1.000 53.02012  ? 108 TRP B CE2 1 
ATOM   3314 C  CE3 . TRP C 1 128 ? -21.50473 -16.38691 34.81800  1.000 49.01544  ? 108 TRP B CE3 1 
ATOM   3315 C  CZ2 . TRP C 1 128 ? -20.52634 -18.80029 35.92547  1.000 53.08057  ? 108 TRP B CZ2 1 
ATOM   3316 C  CZ3 . TRP C 1 128 ? -20.71907 -16.39284 35.95500  1.000 61.66139  ? 108 TRP B CZ3 1 
ATOM   3317 C  CH2 . TRP C 1 128 ? -20.23802 -17.59202 36.49683  1.000 60.84075  ? 108 TRP B CH2 1 
ATOM   3318 N  N   . LEU C 1 129 ? -26.58987 -15.83532 31.50378  1.000 50.91302  ? 109 LEU B N   1 
ATOM   3319 C  CA  . LEU C 1 129 ? -27.36674 -14.98153 30.61416  1.000 51.60576  ? 109 LEU B CA  1 
ATOM   3320 C  C   . LEU C 1 129 ? -27.77238 -13.66737 31.26915  1.000 59.15993  ? 109 LEU B C   1 
ATOM   3321 O  O   . LEU C 1 129 ? -28.35232 -12.80944 30.59482  1.000 63.81405  ? 109 LEU B O   1 
ATOM   3322 C  CB  . LEU C 1 129 ? -28.61173 -15.72764 30.11920  1.000 47.40058  ? 109 LEU B CB  1 
ATOM   3323 C  CG  . LEU C 1 129 ? -28.37667 -16.78630 29.03771  1.000 49.38899  ? 109 LEU B CG  1 
ATOM   3324 C  CD1 . LEU C 1 129 ? -29.67593 -17.47868 28.64663  1.000 45.42717  ? 109 LEU B CD1 1 
ATOM   3325 C  CD2 . LEU C 1 129 ? -27.72439 -16.15478 27.82237  1.000 38.17636  ? 109 LEU B CD2 1 
ATOM   3326 N  N   . THR C 1 130 ? -27.48694 -13.49341 32.55865  1.000 65.66459  ? 110 THR B N   1 
ATOM   3327 C  CA  . THR C 1 130 ? -27.69310 -12.23542 33.26105  1.000 73.38886  ? 110 THR B CA  1 
ATOM   3328 C  C   . THR C 1 130 ? -26.45283 -11.92743 34.08533  1.000 76.68398  ? 110 THR B C   1 
ATOM   3329 O  O   . THR C 1 130 ? -25.85339 -12.82897 34.67929  1.000 73.58580  ? 110 THR B O   1 
ATOM   3330 C  CB  . THR C 1 130 ? -28.92757 -12.28087 34.17715  1.000 80.43573  ? 110 THR B CB  1 
ATOM   3331 O  OG1 . THR C 1 130 ? -28.76389 -13.31505 35.15540  1.000 81.47948  ? 110 THR B OG1 1 
ATOM   3332 C  CG2 . THR C 1 130 ? -30.19056 -12.54415 33.36777  1.000 69.24386  ? 110 THR B CG2 1 
ATOM   3333 N  N   . GLY C 1 131 ? -26.06909 -10.66046 34.11303  1.000 79.54608  ? 111 GLY B N   1 
ATOM   3334 C  CA  . GLY C 1 131 ? -24.90725 -10.21772 34.85579  1.000 68.97483  ? 111 GLY B CA  1 
ATOM   3335 C  C   . GLY C 1 131 ? -23.81476 -9.70101  33.93690  1.000 75.41124  ? 111 GLY B C   1 
ATOM   3336 O  O   . GLY C 1 131 ? -23.99201 -9.54858  32.72508  1.000 77.23289  ? 111 GLY B O   1 
ATOM   3337 N  N   . GLY C 1 132 ? -22.65725 -9.44066  34.54123  1.000 71.55555  ? 112 GLY B N   1 
ATOM   3338 C  CA  . GLY C 1 132 ? -21.54486 -8.85619  33.81900  1.000 64.78662  ? 112 GLY B CA  1 
ATOM   3339 C  C   . GLY C 1 132 ? -20.33370 -9.75344  33.65587  1.000 60.03449  ? 112 GLY B C   1 
ATOM   3340 O  O   . GLY C 1 132 ? -19.19766 -9.29655  33.81490  1.000 57.44595  ? 112 GLY B O   1 
ATOM   3341 N  N   . SER C 1 133 ? -20.55486 -11.02910 33.33317  1.000 55.49169  ? 113 SER B N   1 
ATOM   3342 C  CA  . SER C 1 133 ? -19.45408 -11.93897 33.03848  1.000 54.43086  ? 113 SER B CA  1 
ATOM   3343 C  C   . SER C 1 133 ? -19.09140 -11.98218 31.56022  1.000 49.61498  ? 113 SER B C   1 
ATOM   3344 O  O   . SER C 1 133 ? -17.99753 -12.45005 31.22309  1.000 50.86057  ? 113 SER B O   1 
ATOM   3345 C  CB  . SER C 1 133 ? -19.78510 -13.35782 33.51473  1.000 57.62864  ? 113 SER B CB  1 
ATOM   3346 O  OG  . SER C 1 133 ? -19.39982 -13.54875 34.86510  1.000 47.31357  ? 113 SER B OG  1 
ATOM   3347 N  N   . LEU C 1 134 ? -19.97948 -11.51709 30.67841  1.000 38.94552  ? 114 LEU B N   1 
ATOM   3348 C  CA  . LEU C 1 134 ? -19.69862 -11.42667 29.24415  1.000 40.54142  ? 114 LEU B CA  1 
ATOM   3349 C  C   . LEU C 1 134 ? -19.31282 -12.78720 28.66432  1.000 37.44350  ? 114 LEU B C   1 
ATOM   3350 O  O   . LEU C 1 134 ? -18.35833 -12.90742 27.89293  1.000 35.09506  ? 114 LEU B O   1 
ATOM   3351 C  CB  . LEU C 1 134 ? -18.61196 -10.38446 28.96508  1.000 39.83502  ? 114 LEU B CB  1 
ATOM   3352 C  CG  . LEU C 1 134 ? -18.85384 -8.98515  29.54284  1.000 43.48365  ? 114 LEU B CG  1 
ATOM   3353 C  CD1 . LEU C 1 134 ? -17.67106 -8.06963  29.26568  1.000 32.83731  ? 114 LEU B CD1 1 
ATOM   3354 C  CD2 . LEU C 1 134 ? -20.14260 -8.37819  28.99976  1.000 41.49765  ? 114 LEU B CD2 1 
ATOM   3355 N  N   . VAL C 1 135 ? -20.06523 -13.82383 29.03975  1.000 32.10688  ? 115 VAL B N   1 
ATOM   3356 C  CA  . VAL C 1 135 ? -19.74301 -15.17483 28.59117  1.000 31.31827  ? 115 VAL B CA  1 
ATOM   3357 C  C   . VAL C 1 135 ? -19.99517 -15.32040 27.09511  1.000 29.17197  ? 115 VAL B C   1 
ATOM   3358 O  O   . VAL C 1 135 ? -19.23371 -15.99144 26.38631  1.000 34.17139  ? 115 VAL B O   1 
ATOM   3359 C  CB  . VAL C 1 135 ? -20.53416 -16.20809 29.41311  1.000 26.03819  ? 115 VAL B CB  1 
ATOM   3360 C  CG1 . VAL C 1 135 ? -20.24913 -17.61508 28.91671  1.000 29.39997  ? 115 VAL B CG1 1 
ATOM   3361 C  CG2 . VAL C 1 135 ? -20.16826 -16.08716 30.87835  1.000 31.28068  ? 115 VAL B CG2 1 
ATOM   3362 N  N   . GLY C 1 136 ? -21.05903 -14.69481 26.58837  1.000 24.05782  ? 116 GLY B N   1 
ATOM   3363 C  CA  . GLY C 1 136 ? -21.29121 -14.70970 25.15316  1.000 24.95355  ? 116 GLY B CA  1 
ATOM   3364 C  C   . GLY C 1 136 ? -20.15285 -14.07476 24.37956  1.000 30.90751  ? 116 GLY B C   1 
ATOM   3365 O  O   . GLY C 1 136 ? -19.75765 -14.56631 23.31818  1.000 38.69503  ? 116 GLY B O   1 
ATOM   3366 N  N   . LEU C 1 137 ? -19.60286 -12.97919 24.90893  1.000 34.53034  ? 117 LEU B N   1 
ATOM   3367 C  CA  . LEU C 1 137 ? -18.44029 -12.35360 24.28909  1.000 30.68766  ? 117 LEU B CA  1 
ATOM   3368 C  C   . LEU C 1 137 ? -17.23489 -13.28485 24.31304  1.000 32.67246  ? 117 LEU B C   1 
ATOM   3369 O  O   . LEU C 1 137 ? -16.49873 -13.37806 23.32505  1.000 34.80738  ? 117 LEU B O   1 
ATOM   3370 C  CB  . LEU C 1 137 ? -18.11701 -11.03670 24.99396  1.000 29.17360  ? 117 LEU B CB  1 
ATOM   3371 C  CG  . LEU C 1 137 ? -16.82964 -10.33063 24.56384  1.000 30.25992  ? 117 LEU B CG  1 
ATOM   3372 C  CD1 . LEU C 1 137 ? -16.90812 -9.91540  23.10153  1.000 27.68575  ? 117 LEU B CD1 1 
ATOM   3373 C  CD2 . LEU C 1 137 ? -16.54856 -9.13166  25.46117  1.000 26.71164  ? 117 LEU B CD2 1 
ATOM   3374 N  N   . ARG C 1 138 ? -17.01426 -13.97853 25.43541  1.000 31.93007  ? 118 ARG B N   1 
ATOM   3375 C  CA  . ARG C 1 138 ? -15.92390 -14.94763 25.50541  1.000 38.31498  ? 118 ARG B CA  1 
ATOM   3376 C  C   . ARG C 1 138 ? -16.08094 -16.02548 24.44050  1.000 32.15060  ? 118 ARG B C   1 
ATOM   3377 O  O   . ARG C 1 138 ? -15.11766 -16.36768 23.74289  1.000 35.57382  ? 118 ARG B O   1 
ATOM   3378 C  CB  . ARG C 1 138 ? -15.86451 -15.58131 26.89799  1.000 37.80253  ? 118 ARG B CB  1 
ATOM   3379 C  CG  . ARG C 1 138 ? -15.57468 -14.61252 28.03830  1.000 41.29487  ? 118 ARG B CG  1 
ATOM   3380 C  CD  . ARG C 1 138 ? -15.62161 -15.32656 29.38643  1.000 44.79595  ? 118 ARG B CD  1 
ATOM   3381 N  NE  . ARG C 1 138 ? -15.47739 -14.40877 30.51199  1.000 50.49848  ? 118 ARG B NE  1 
ATOM   3382 C  CZ  . ARG C 1 138 ? -14.34865 -14.20704 31.17822  1.000 51.68764  ? 118 ARG B CZ  1 
ATOM   3383 N  NH1 . ARG C 1 138 ? -13.23476 -14.84570 30.86058  1.000 44.93199  ? 118 ARG B NH1 1 
ATOM   3384 N  NH2 . ARG C 1 138 ? -14.33856 -13.34489 32.19073  1.000 47.73338  ? 118 ARG B NH2 1 
ATOM   3385 N  N   . CYS C 1 139 ? -17.29637 -16.55880 24.29135  1.000 33.31650  ? 119 CYS B N   1 
ATOM   3386 C  CA  . CYS C 1 139 ? -17.53505 -17.61102 23.30817  1.000 33.53092  ? 119 CYS B CA  1 
ATOM   3387 C  C   . CYS C 1 139 ? -17.33075 -17.10323 21.88494  1.000 30.74362  ? 119 CYS B C   1 
ATOM   3388 O  O   . CYS C 1 139 ? -16.69294 -17.77746 21.06877  1.000 27.53833  ? 119 CYS B O   1 
ATOM   3389 C  CB  . CYS C 1 139 ? -18.94385 -18.18010 23.47974  1.000 32.60482  ? 119 CYS B CB  1 
ATOM   3390 S  SG  . CYS C 1 139 ? -19.27035 -18.91566 25.10225  1.000 31.63207  ? 119 CYS B SG  1 
ATOM   3391 N  N   . LEU C 1 140 ? -17.85730 -15.91732 21.56678  1.000 31.13173  ? 120 LEU B N   1 
ATOM   3392 C  CA  . LEU C 1 140 ? -17.69539 -15.38325 20.21660  1.000 30.51094  ? 120 LEU B CA  1 
ATOM   3393 C  C   . LEU C 1 140 ? -16.23465 -15.07732 19.90932  1.000 35.93881  ? 120 LEU B C   1 
ATOM   3394 O  O   . LEU C 1 140 ? -15.76290 -15.33019 18.79299  1.000 35.26847  ? 120 LEU B O   1 
ATOM   3395 C  CB  . LEU C 1 140 ? -18.55906 -14.13703 20.03665  1.000 32.11927  ? 120 LEU B CB  1 
ATOM   3396 C  CG  . LEU C 1 140 ? -19.99440 -14.44654 19.61466  1.000 46.81009  ? 120 LEU B CG  1 
ATOM   3397 C  CD1 . LEU C 1 140 ? -20.85857 -13.19998 19.63032  1.000 38.74484  ? 120 LEU B CD1 1 
ATOM   3398 C  CD2 . LEU C 1 140 ? -19.99130 -15.07387 18.23400  1.000 43.24848  ? 120 LEU B CD2 1 
ATOM   3399 N  N   . ARG C 1 141 ? -15.50138 -14.54134 20.88806  1.000 32.56470  ? 121 ARG B N   1 
ATOM   3400 C  CA  . ARG C 1 141 ? -14.08084 -14.27504 20.69617  1.000 33.68091  ? 121 ARG B CA  1 
ATOM   3401 C  C   . ARG C 1 141 ? -13.30640 -15.56439 20.47017  1.000 41.16019  ? 121 ARG B C   1 
ATOM   3402 O  O   . ARG C 1 141 ? -12.43800 -15.63146 19.58978  1.000 37.42408  ? 121 ARG B O   1 
ATOM   3403 C  CB  . ARG C 1 141 ? -13.52922 -13.51971 21.90494  1.000 37.77885  ? 121 ARG B CB  1 
ATOM   3404 C  CG  . ARG C 1 141 ? -13.84990 -12.03618 21.90153  1.000 40.94494  ? 121 ARG B CG  1 
ATOM   3405 C  CD  . ARG C 1 141 ? -13.00811 -11.32627 20.86045  1.000 43.64809  ? 121 ARG B CD  1 
ATOM   3406 N  NE  . ARG C 1 141 ? -11.58659 -11.45449 21.15774  1.000 47.81452  ? 121 ARG B NE  1 
ATOM   3407 C  CZ  . ARG C 1 141 ? -10.61874 -11.33919 20.25943  1.000 54.98796  ? 121 ARG B CZ  1 
ATOM   3408 N  NH1 . ARG C 1 141 ? -10.88339 -11.11929 18.98125  1.000 49.62114  ? 121 ARG B NH1 1 
ATOM   3409 N  NH2 . ARG C 1 141 ? -9.35394  -11.45963 20.65132  1.000 52.57952  ? 121 ARG B NH2 1 
ATOM   3410 N  N   . ARG C 1 142 ? -13.60327 -16.59915 21.26065  1.000 31.75068  ? 122 ARG B N   1 
ATOM   3411 C  CA  . ARG C 1 142 ? -12.94450 -17.88285 21.06398  1.000 29.85622  ? 122 ARG B CA  1 
ATOM   3412 C  C   . ARG C 1 142 ? -13.26646 -18.45541 19.69192  1.000 30.98553  ? 122 ARG B C   1 
ATOM   3413 O  O   . ARG C 1 142 ? -12.39544 -19.03600 19.03690  1.000 34.36445  ? 122 ARG B O   1 
ATOM   3414 C  CB  . ARG C 1 142 ? -13.35640 -18.85944 22.16230  1.000 29.15343  ? 122 ARG B CB  1 
ATOM   3415 C  CG  . ARG C 1 142 ? -12.61034 -20.18074 22.13296  1.000 30.64693  ? 122 ARG B CG  1 
ATOM   3416 C  CD  . ARG C 1 142 ? -11.18465 -20.02836 22.63210  1.000 22.68349  ? 122 ARG B CD  1 
ATOM   3417 N  NE  . ARG C 1 142 ? -10.50901 -21.31596 22.72265  1.000 36.47113  ? 122 ARG B NE  1 
ATOM   3418 C  CZ  . ARG C 1 142 ? -9.31753  -21.50311 23.27356  1.000 41.99270  ? 122 ARG B CZ  1 
ATOM   3419 N  NH1 . ARG C 1 142 ? -8.64271  -20.50431 23.81779  1.000 42.40033  ? 122 ARG B NH1 1 
ATOM   3420 N  NH2 . ARG C 1 142 ? -8.78983  -22.72443 23.27953  1.000 35.90573  ? 122 ARG B NH2 1 
ATOM   3421 N  N   . ALA C 1 143 ? -14.51114 -18.29675 19.23636  1.000 28.47006  ? 123 ALA B N   1 
ATOM   3422 C  CA  . ALA C 1 143 ? -14.88150 -18.80608 17.91996  1.000 36.42005  ? 123 ALA B CA  1 
ATOM   3423 C  C   . ALA C 1 143 ? -14.10821 -18.08979 16.82034  1.000 38.53028  ? 123 ALA B C   1 
ATOM   3424 O  O   . ALA C 1 143 ? -13.57532 -18.72776 15.90298  1.000 33.50575  ? 123 ALA B O   1 
ATOM   3425 C  CB  . ALA C 1 143 ? -16.39006 -18.66935 17.70661  1.000 25.83844  ? 123 ALA B CB  1 
ATOM   3426 N  N   . ILE C 1 144 ? -14.03607 -16.75827 16.90469  1.000 41.15751  ? 124 ILE B N   1 
ATOM   3427 C  CA  . ILE C 1 144 ? -13.30609 -15.96909 15.91443  1.000 39.18396  ? 124 ILE B CA  1 
ATOM   3428 C  C   . ILE C 1 144 ? -11.83289 -16.36959 15.88948  1.000 39.42767  ? 124 ILE B C   1 
ATOM   3429 O  O   . ILE C 1 144 ? -11.25197 -16.60052 14.82138  1.000 36.79087  ? 124 ILE B O   1 
ATOM   3430 C  CB  . ILE C 1 144 ? -13.48292 -14.46627 16.20351  1.000 43.14520  ? 124 ILE B CB  1 
ATOM   3431 C  CG1 . ILE C 1 144 ? -14.93998 -14.04659 15.99573  1.000 34.26914  ? 124 ILE B CG1 1 
ATOM   3432 C  CG2 . ILE C 1 144 ? -12.55767 -13.63258 15.33075  1.000 36.02462  ? 124 ILE B CG2 1 
ATOM   3433 C  CD1 . ILE C 1 144 ? -15.27066 -12.69015 16.57671  1.000 33.73978  ? 124 ILE B CD1 1 
ATOM   3434 N  N   . GLU C 1 145 ? -11.20559 -16.46082 17.06708  1.000 39.27604  ? 125 GLU B N   1 
ATOM   3435 C  CA  . GLU C 1 145 ? -9.78297  -16.79034 17.11748  1.000 40.20451  ? 125 GLU B CA  1 
ATOM   3436 C  C   . GLU C 1 145 ? -9.51717  -18.20901 16.62518  1.000 43.42320  ? 125 GLU B C   1 
ATOM   3437 O  O   . GLU C 1 145 ? -8.52703  -18.45065 15.92695  1.000 42.37622  ? 125 GLU B O   1 
ATOM   3438 C  CB  . GLU C 1 145 ? -9.25050  -16.60413 18.53736  1.000 38.38486  ? 125 GLU B CB  1 
ATOM   3439 C  CG  . GLU C 1 145 ? -9.13275  -15.14828 18.96192  1.000 53.91191  ? 125 GLU B CG  1 
ATOM   3440 C  CD  . GLU C 1 145 ? -9.05210  -14.98477 20.46631  1.000 70.79989  ? 125 GLU B CD  1 
ATOM   3441 O  OE1 . GLU C 1 145 ? -9.04496  -16.01165 21.18042  1.000 82.24589  ? 125 GLU B OE1 1 
ATOM   3442 O  OE2 . GLU C 1 145 ? -9.00527  -13.82770 20.93478  1.000 71.40976  ? 125 GLU B OE2 1 
ATOM   3443 N  N   . THR C 1 146 ? -10.38408 -19.16132 16.97769  1.000 42.74908  ? 126 THR B N   1 
ATOM   3444 C  CA  . THR C 1 146 ? -10.20111 -20.53372 16.52218  1.000 33.91442  ? 126 THR B CA  1 
ATOM   3445 C  C   . THR C 1 146 ? -10.35724 -20.63453 15.01206  1.000 40.17571  ? 126 THR B C   1 
ATOM   3446 O  O   . THR C 1 146 ? -9.58762  -21.33796 14.34623  1.000 33.81787  ? 126 THR B O   1 
ATOM   3447 C  CB  . THR C 1 146 ? -11.19981 -21.45197 17.22578  1.000 29.61836  ? 126 THR B CB  1 
ATOM   3448 O  OG1 . THR C 1 146 ? -11.15965 -21.20664 18.63698  1.000 34.39552  ? 126 THR B OG1 1 
ATOM   3449 C  CG2 . THR C 1 146 ? -10.86497 -22.91375 16.96187  1.000 29.81884  ? 126 THR B CG2 1 
ATOM   3450 N  N   . ALA C 1 147 ? -11.34437 -19.93060 14.45122  1.000 36.51478  ? 127 ALA B N   1 
ATOM   3451 C  CA  . ALA C 1 147 ? -11.53564 -19.95481 13.00606  1.000 44.82349  ? 127 ALA B CA  1 
ATOM   3452 C  C   . ALA C 1 147 ? -10.36475 -19.29913 12.28409  1.000 46.48485  ? 127 ALA B C   1 
ATOM   3453 O  O   . ALA C 1 147 ? -9.93768  -19.77347 11.22438  1.000 43.14366  ? 127 ALA B O   1 
ATOM   3454 C  CB  . ALA C 1 147 ? -12.85351 -19.27093 12.64307  1.000 36.55602  ? 127 ALA B CB  1 
ATOM   3455 N  N   . ALA C 1 148 ? -9.82185  -18.21739 12.84866  1.000 40.57349  ? 128 ALA B N   1 
ATOM   3456 C  CA  . ALA C 1 148 ? -8.67007  -17.57080 12.23053  1.000 36.80389  ? 128 ALA B CA  1 
ATOM   3457 C  C   . ALA C 1 148 ? -7.42965  -18.45901 12.29991  1.000 42.48372  ? 128 ALA B C   1 
ATOM   3458 O  O   . ALA C 1 148 ? -6.69968  -18.58929 11.31039  1.000 45.15969  ? 128 ALA B O   1 
ATOM   3459 C  CB  . ALA C 1 148 ? -8.41835  -16.21449 12.89156  1.000 39.77466  ? 128 ALA B CB  1 
ATOM   3460 N  N   . GLN C 1 149 ? -7.18370  -19.09017 13.45306  1.000 40.83493  ? 129 GLN B N   1 
ATOM   3461 C  CA  . GLN C 1 149 ? -6.02769  -19.97237 13.59507  1.000 37.45435  ? 129 GLN B CA  1 
ATOM   3462 C  C   . GLN C 1 149 ? -6.14205  -21.18427 12.68081  1.000 40.20072  ? 129 GLN B C   1 
ATOM   3463 O  O   . GLN C 1 149 ? -5.14365  -21.63419 12.11084  1.000 42.05419  ? 129 GLN B O   1 
ATOM   3464 C  CB  . GLN C 1 149 ? -5.88463  -20.41932 15.04829  1.000 32.39936  ? 129 GLN B CB  1 
ATOM   3465 C  CG  . GLN C 1 149 ? -5.43868  -19.31353 15.99320  1.000 49.47512  ? 129 GLN B CG  1 
ATOM   3466 C  CD  . GLN C 1 149 ? -5.39662  -19.77940 17.43603  1.000 57.35996  ? 129 GLN B CD  1 
ATOM   3467 O  OE1 . GLN C 1 149 ? -5.00284  -20.91190 17.72248  1.000 63.10611  ? 129 GLN B OE1 1 
ATOM   3468 N  NE2 . GLN C 1 149 ? -5.80981  -18.91254 18.35191  1.000 55.39218  ? 129 GLN B NE2 1 
ATOM   3469 N  N   . ALA C 1 150 ? -7.35817  -21.74215 12.53564  1.000 40.92029  ? 130 ALA B N   1 
ATOM   3470 C  CA  . ALA C 1 150 ? -7.59028  -22.84668 11.60083  1.000 38.54362  ? 130 ALA B CA  1 
ATOM   3471 C  C   . ALA C 1 150 ? -7.38473  -22.42711 10.12551  1.000 41.02547  ? 130 ALA B C   1 
ATOM   3472 O  O   . ALA C 1 150 ? -7.69496  -23.22453 9.24402   1.000 41.65604  ? 130 ALA B O   1 
ATOM   3473 C  CB  . ALA C 1 150 ? -8.99812  -23.40796 11.78032  1.000 30.85091  ? 130 ALA B CB  1 
ATOM   3474 N  N   . GLY C 1 151 ? -6.86597  -21.23052 9.84217   1.000 45.51190  ? 131 GLY B N   1 
ATOM   3475 C  CA  . GLY C 1 151 ? -6.65439  -20.80189 8.46636   1.000 40.02156  ? 131 GLY B CA  1 
ATOM   3476 C  C   . GLY C 1 151 ? -7.88243  -20.25220 7.78176   1.000 48.23848  ? 131 GLY B C   1 
ATOM   3477 O  O   . GLY C 1 151 ? -7.95500  -20.26134 6.54989   1.000 56.44033  ? 131 GLY B O   1 
ATOM   3478 N  N   . GLY C 1 152 ? -8.84916  -19.76044 8.55146   1.000 49.97760  ? 132 GLY B N   1 
ATOM   3479 C  CA  . GLY C 1 152 ? -10.12918 -19.39869 7.98739   1.000 40.77701  ? 132 GLY B CA  1 
ATOM   3480 C  C   . GLY C 1 152 ? -10.10967 -18.05087 7.29099   1.000 50.63266  ? 132 GLY B C   1 
ATOM   3481 O  O   . GLY C 1 152 ? -9.43690  -17.10727 7.70952   1.000 46.68333  ? 132 GLY B O   1 
ATOM   3482 N  N   . ASP C 1 153 ? -10.86099 -17.97803 6.19300   1.000 58.54944  ? 133 ASP B N   1 
ATOM   3483 C  CA  . ASP C 1 153 ? -11.02522 -16.74355 5.43923   1.000 59.64787  ? 133 ASP B CA  1 
ATOM   3484 C  C   . ASP C 1 153 ? -12.15863 -15.87945 5.97874   1.000 52.96655  ? 133 ASP B C   1 
ATOM   3485 O  O   . ASP C 1 153 ? -12.07113 -14.64612 5.92797   1.000 48.37867  ? 133 ASP B O   1 
ATOM   3486 C  CB  . ASP C 1 153 ? -11.28209 -17.07235 3.96671   1.000 47.73264  ? 133 ASP B CB  1 
ATOM   3487 C  CG  . ASP C 1 153 ? -10.98046 -15.91404 3.05038   1.000 59.48106  ? 133 ASP B CG  1 
ATOM   3488 O  OD1 . ASP C 1 153 ? -9.80465  -15.75649 2.65720   1.000 73.93694  ? 133 ASP B OD1 1 
ATOM   3489 O  OD2 . ASP C 1 153 ? -11.91797 -15.15757 2.72377   1.000 70.38830  ? 133 ASP B OD2 1 
ATOM   3490 N  N   . ALA C 1 154 ? -13.21310 -16.49823 6.50454   1.000 49.13612  ? 134 ALA B N   1 
ATOM   3491 C  CA  . ALA C 1 154 ? -14.37195 -15.76527 6.99205   1.000 46.42581  ? 134 ALA B CA  1 
ATOM   3492 C  C   . ALA C 1 154 ? -15.13870 -16.64897 7.96321   1.000 42.20753  ? 134 ALA B C   1 
ATOM   3493 O  O   . ALA C 1 154 ? -15.00025 -17.87461 7.95869   1.000 41.65598  ? 134 ALA B O   1 
ATOM   3494 C  CB  . ALA C 1 154 ? -15.27891 -15.31655 5.84027   1.000 38.12008  ? 134 ALA B CB  1 
ATOM   3495 N  N   . LEU C 1 155 ? -15.95517 -16.00867 8.79524   1.000 32.49917  ? 135 LEU B N   1 
ATOM   3496 C  CA  . LEU C 1 155 ? -16.81454 -16.70221 9.74792   1.000 31.66967  ? 135 LEU B CA  1 
ATOM   3497 C  C   . LEU C 1 155 ? -18.25879 -16.35566 9.41488   1.000 30.73386  ? 135 LEU B C   1 
ATOM   3498 O  O   . LEU C 1 155 ? -18.66559 -15.19348 9.52353   1.000 33.59259  ? 135 LEU B O   1 
ATOM   3499 C  CB  . LEU C 1 155 ? -16.46755 -16.32211 11.18565  1.000 28.49932  ? 135 LEU B CB  1 
ATOM   3500 C  CG  . LEU C 1 155 ? -17.20299 -17.10177 12.27504  1.000 32.09296  ? 135 LEU B CG  1 
ATOM   3501 C  CD1 . LEU C 1 155 ? -17.11389 -18.60164 12.01554  1.000 27.09961  ? 135 LEU B CD1 1 
ATOM   3502 C  CD2 . LEU C 1 155 ? -16.62724 -16.75472 13.63719  1.000 27.91615  ? 135 LEU B CD2 1 
ATOM   3503 N  N   . ARG C 1 156 ? -19.02201 -17.35808 8.99421   1.000 34.38707  ? 136 ARG B N   1 
ATOM   3504 C  CA  . ARG C 1 156 ? -20.41464 -17.18869 8.61439   1.000 39.68841  ? 136 ARG B CA  1 
ATOM   3505 C  C   . ARG C 1 156 ? -21.31999 -17.78934 9.68138   1.000 38.09846  ? 136 ARG B C   1 
ATOM   3506 O  O   . ARG C 1 156 ? -20.94338 -18.73899 10.37506  1.000 35.85525  ? 136 ARG B O   1 
ATOM   3507 C  CB  . ARG C 1 156 ? -20.69236 -17.85138 7.26022   1.000 31.92901  ? 136 ARG B CB  1 
ATOM   3508 C  CG  . ARG C 1 156 ? -19.82692 -17.32241 6.12711   1.000 42.79339  ? 136 ARG B CG  1 
ATOM   3509 C  CD  . ARG C 1 156 ? -19.95948 -18.16756 4.87066   1.000 48.39082  ? 136 ARG B CD  1 
ATOM   3510 N  NE  . ARG C 1 156 ? -19.27662 -17.56152 3.73292   1.000 51.98075  ? 136 ARG B NE  1 
ATOM   3511 C  CZ  . ARG C 1 156 ? -19.16823 -18.12259 2.53593   1.000 48.48807  ? 136 ARG B CZ  1 
ATOM   3512 N  NH1 . ARG C 1 156 ? -19.66965 -19.32102 2.28582   1.000 40.93141  ? 136 ARG B NH1 1 
ATOM   3513 N  NH2 . ARG C 1 156 ? -18.54054 -17.46474 1.56542   1.000 41.15898  ? 136 ARG B NH2 1 
ATOM   3514 N  N   . SER C 1 157 ? -22.51765 -17.22594 9.81544   1.000 34.36715  ? 137 SER B N   1 
ATOM   3515 C  CA  . SER C 1 157 ? -23.45976 -17.77226 10.78340  1.000 41.80032  ? 137 SER B CA  1 
ATOM   3516 C  C   . SER C 1 157 ? -24.88069 -17.42860 10.36332  1.000 41.34998  ? 137 SER B C   1 
ATOM   3517 O  O   . SER C 1 157 ? -25.11510 -16.49455 9.59269   1.000 42.41522  ? 137 SER B O   1 
ATOM   3518 C  CB  . SER C 1 157 ? -23.18168 -17.25806 12.20176  1.000 33.89213  ? 137 SER B CB  1 
ATOM   3519 O  OG  . SER C 1 157 ? -23.69085 -15.94769 12.38087  1.000 49.05153  ? 137 SER B OG  1 
ATOM   3520 N  N   . GLU C 1 158 ? -25.82689 -18.20246 10.88694  1.000 42.86481  ? 138 GLU B N   1 
ATOM   3521 C  CA  . GLU C 1 158 ? -27.24850 -17.91039 10.76966  1.000 42.96047  ? 138 GLU B CA  1 
ATOM   3522 C  C   . GLU C 1 158 ? -27.77143 -17.56372 12.15663  1.000 42.00678  ? 138 GLU B C   1 
ATOM   3523 O  O   . GLU C 1 158 ? -27.64675 -18.36683 13.08789  1.000 40.61293  ? 138 GLU B O   1 
ATOM   3524 C  CB  . GLU C 1 158 ? -28.01543 -19.09534 10.18055  1.000 39.92708  ? 138 GLU B CB  1 
ATOM   3525 C  CG  . GLU C 1 158 ? -29.48864 -18.80567 9.95156   1.000 46.18310  ? 138 GLU B CG  1 
ATOM   3526 C  CD  . GLU C 1 158 ? -30.24471 -19.99631 9.40143   1.000 53.07343  ? 138 GLU B CD  1 
ATOM   3527 O  OE1 . GLU C 1 158 ? -30.41562 -20.99060 10.13870  1.000 58.00056  ? 138 GLU B OE1 1 
ATOM   3528 O  OE2 . GLU C 1 158 ? -30.65865 -19.94088 8.22439   1.000 62.11066  ? 138 GLU B OE2 1 
ATOM   3529 N  N   . ALA C 1 159 ? -28.35565 -16.37690 12.29197  1.000 38.88356  ? 139 ALA B N   1 
ATOM   3530 C  CA  . ALA C 1 159 ? -28.80165 -15.87504 13.58190  1.000 38.28811  ? 139 ALA B CA  1 
ATOM   3531 C  C   . ALA C 1 159 ? -30.28988 -15.55808 13.55054  1.000 37.46911  ? 139 ALA B C   1 
ATOM   3532 O  O   . ALA C 1 159 ? -30.87608 -15.30639 12.49450  1.000 39.36225  ? 139 ALA B O   1 
ATOM   3533 C  CB  . ALA C 1 159 ? -28.01787 -14.62098 13.99536  1.000 37.08708  ? 139 ALA B CB  1 
ATOM   3534 N  N   . ASN C 1 160 ? -30.89485 -15.57407 14.73632  1.000 40.70035  ? 140 ASN B N   1 
ATOM   3535 C  CA  . ASN C 1 160 ? -32.27899 -15.16469 14.89869  1.000 40.74772  ? 140 ASN B CA  1 
ATOM   3536 C  C   . ASN C 1 160 ? -32.29294 -13.71384 15.34987  1.000 40.24212  ? 140 ASN B C   1 
ATOM   3537 O  O   . ASN C 1 160 ? -31.85817 -13.42373 16.47471  1.000 41.88147  ? 140 ASN B O   1 
ATOM   3538 C  CB  . ASN C 1 160 ? -32.98877 -16.05302 15.91976  1.000 41.14517  ? 140 ASN B CB  1 
ATOM   3539 C  CG  . ASN C 1 160 ? -34.49973 -15.86349 15.91826  1.000 51.32240  ? 140 ASN B CG  1 
ATOM   3540 O  OD1 . ASN C 1 160 ? -35.00399 -14.76060 15.70128  1.000 44.98491  ? 140 ASN B OD1 1 
ATOM   3541 N  ND2 . ASN C 1 160 ? -35.22906 -16.94604 16.16501  1.000 55.92574  ? 140 ASN B ND2 1 
ATOM   3542 N  N   . PRO C 1 161 ? -32.76340 -12.77297 14.52564  1.000 45.17702  ? 141 PRO B N   1 
ATOM   3543 C  CA  . PRO C 1 161 ? -32.75524 -11.36305 14.94681  1.000 38.98839  ? 141 PRO B CA  1 
ATOM   3544 C  C   . PRO C 1 161 ? -33.65896 -11.07630 16.13295  1.000 39.64605  ? 141 PRO B C   1 
ATOM   3545 O  O   . PRO C 1 161 ? -33.47595 -10.04312 16.78943  1.000 39.92479  ? 141 PRO B O   1 
ATOM   3546 C  CB  . PRO C 1 161 ? -33.22512 -10.61794 13.69019  1.000 40.67733  ? 141 PRO B CB  1 
ATOM   3547 C  CG  . PRO C 1 161 ? -34.01873 -11.62916 12.93563  1.000 45.07837  ? 141 PRO B CG  1 
ATOM   3548 C  CD  . PRO C 1 161 ? -33.34460 -12.94661 13.18387  1.000 43.28252  ? 141 PRO B CD  1 
ATOM   3549 N  N   . ASP C 1 162 ? -34.61863 -11.95276 16.43540  1.000 41.56739  ? 142 ASP B N   1 
ATOM   3550 C  CA  . ASP C 1 162 ? -35.48057 -11.75920 17.59370  1.000 48.91282  ? 142 ASP B CA  1 
ATOM   3551 C  C   . ASP C 1 162 ? -34.78156 -12.07309 18.90920  1.000 41.17138  ? 142 ASP B C   1 
ATOM   3552 O  O   . ASP C 1 162 ? -35.31929 -11.73948 19.97053  1.000 45.06122  ? 142 ASP B O   1 
ATOM   3553 C  CB  . ASP C 1 162 ? -36.74942 -12.60719 17.46076  1.000 49.01382  ? 142 ASP B CB  1 
ATOM   3554 C  CG  . ASP C 1 162 ? -37.70526 -12.06264 16.41600  1.000 52.76676  ? 142 ASP B CG  1 
ATOM   3555 O  OD1 . ASP C 1 162 ? -37.39311 -11.01241 15.81590  1.000 52.12844  ? 142 ASP B OD1 1 
ATOM   3556 O  OD2 . ASP C 1 162 ? -38.76767 -12.68178 16.19401  1.000 67.89100  ? 142 ASP B OD2 1 
ATOM   3557 N  N   . LEU C 1 163 ? -33.61339 -12.71274 18.86954  1.000 43.97731  ? 143 LEU B N   1 
ATOM   3558 C  CA  . LEU C 1 163 ? -32.74650 -12.82125 20.04239  1.000 40.99770  ? 143 LEU B CA  1 
ATOM   3559 C  C   . LEU C 1 163 ? -31.90464 -11.55243 20.06507  1.000 39.56102  ? 143 LEU B C   1 
ATOM   3560 O  O   . LEU C 1 163 ? -30.79922 -11.49946 19.52319  1.000 42.97121  ? 143 LEU B O   1 
ATOM   3561 C  CB  . LEU C 1 163 ? -31.89733 -14.08517 19.98421  1.000 41.12456  ? 143 LEU B CB  1 
ATOM   3562 C  CG  . LEU C 1 163 ? -32.68285 -15.39961 19.93427  1.000 44.52144  ? 143 LEU B CG  1 
ATOM   3563 C  CD1 . LEU C 1 163 ? -31.75294 -16.60732 19.97266  1.000 39.23656  ? 143 LEU B CD1 1 
ATOM   3564 C  CD2 . LEU C 1 163 ? -33.69537 -15.46272 21.06716  1.000 38.06760  ? 143 LEU B CD2 1 
ATOM   3565 N  N   . SER C 1 164 ? -32.44923 -10.51238 20.70142  1.000 42.15447  ? 144 SER B N   1 
ATOM   3566 C  CA  . SER C 1 164 ? -31.92036 -9.16262  20.53025  1.000 37.33581  ? 144 SER B CA  1 
ATOM   3567 C  C   . SER C 1 164 ? -30.51485 -9.02249  21.10139  1.000 36.57997  ? 144 SER B C   1 
ATOM   3568 O  O   . SER C 1 164 ? -29.64935 -8.39850  20.47648  1.000 36.94165  ? 144 SER B O   1 
ATOM   3569 C  CB  . SER C 1 164 ? -32.86867 -8.15335  21.17388  1.000 39.10447  ? 144 SER B CB  1 
ATOM   3570 O  OG  . SER C 1 164 ? -34.14635 -8.21310  20.56372  1.000 56.43896  ? 144 SER B OG  1 
ATOM   3571 N  N   . ALA C 1 165 ? -30.26821 -9.58744  22.28536  1.000 41.75865  ? 145 ALA B N   1 
ATOM   3572 C  CA  . ALA C 1 165 ? -28.94936 -9.46829  22.90057  1.000 33.70155  ? 145 ALA B CA  1 
ATOM   3573 C  C   . ALA C 1 165 ? -27.88225 -10.13285 22.04080  1.000 38.39799  ? 145 ALA B C   1 
ATOM   3574 O  O   . ALA C 1 165 ? -26.82473 -9.54757  21.77810  1.000 37.55635  ? 145 ALA B O   1 
ATOM   3575 C  CB  . ALA C 1 165 ? -28.96679 -10.07506 24.30379  1.000 26.96953  ? 145 ALA B CB  1 
ATOM   3576 N  N   . THR C 1 166 ? -28.15126 -11.35824 21.58357  1.000 35.10919  ? 146 THR B N   1 
ATOM   3577 C  CA  . THR C 1 166 ? -27.19029 -12.07476 20.75093  1.000 32.09248  ? 146 THR B CA  1 
ATOM   3578 C  C   . THR C 1 166 ? -27.00244 -11.38836 19.40343  1.000 34.06443  ? 146 THR B C   1 
ATOM   3579 O  O   . THR C 1 166 ? -25.87761 -11.30056 18.89791  1.000 36.33328  ? 146 THR B O   1 
ATOM   3580 C  CB  . THR C 1 166 ? -27.64513 -13.52098 20.55627  1.000 36.89497  ? 146 THR B CB  1 
ATOM   3581 O  OG1 . THR C 1 166 ? -27.89149 -14.12180 21.83368  1.000 33.17102  ? 146 THR B OG1 1 
ATOM   3582 C  CG2 . THR C 1 166 ? -26.57984 -14.32351 19.82034  1.000 37.68298  ? 146 THR B CG2 1 
ATOM   3583 N  N   . ARG C 1 167 ? -28.09085 -10.89484 18.80769  1.000 32.75264  ? 147 ARG B N   1 
ATOM   3584 C  CA  . ARG C 1 167 ? -27.98244 -10.19271 17.53214  1.000 42.24452  ? 147 ARG B CA  1 
ATOM   3585 C  C   . ARG C 1 167 ? -27.12830 -8.93687  17.66751  1.000 41.84504  ? 147 ARG B C   1 
ATOM   3586 O  O   . ARG C 1 167 ? -26.24933 -8.67659  16.83319  1.000 35.96254  ? 147 ARG B O   1 
ATOM   3587 C  CB  . ARG C 1 167 ? -29.37767 -9.84663  17.00809  1.000 30.27173  ? 147 ARG B CB  1 
ATOM   3588 C  CG  . ARG C 1 167 ? -29.37923 -9.13925  15.66462  1.000 41.03617  ? 147 ARG B CG  1 
ATOM   3589 C  CD  . ARG C 1 167 ? -28.81766 -10.03229 14.56734  1.000 37.41691  ? 147 ARG B CD  1 
ATOM   3590 N  NE  . ARG C 1 167 ? -28.59134 -9.28989  13.33363  1.000 40.81094  ? 147 ARG B NE  1 
ATOM   3591 C  CZ  . ARG C 1 167 ? -27.46111 -8.66285  13.03690  1.000 38.12750  ? 147 ARG B CZ  1 
ATOM   3592 N  NH1 . ARG C 1 167 ? -26.42384 -8.68356  13.85747  1.000 39.27567  ? 147 ARG B NH1 1 
ATOM   3593 N  NH2 . ARG C 1 167 ? -27.36976 -7.99588  11.88963  1.000 33.53453  ? 147 ARG B NH2 1 
ATOM   3594 N  N   . SER C 1 168 ? -27.36041 -8.15663  18.72735  1.000 40.36729  ? 148 SER B N   1 
ATOM   3595 C  CA  . SER C 1 168 ? -26.57744 -6.94668  18.95273  1.000 36.14087  ? 148 SER B CA  1 
ATOM   3596 C  C   . SER C 1 168 ? -25.11671 -7.27604  19.23738  1.000 38.63701  ? 148 SER B C   1 
ATOM   3597 O  O   . SER C 1 168 ? -24.21514 -6.58124  18.75551  1.000 35.55231  ? 148 SER B O   1 
ATOM   3598 C  CB  . SER C 1 168 ? -27.18432 -6.14060  20.10145  1.000 31.34441  ? 148 SER B CB  1 
ATOM   3599 O  OG  . SER C 1 168 ? -26.43458 -4.96571  20.35792  1.000 50.85454  ? 148 SER B OG  1 
ATOM   3600 N  N   . LEU C 1 169 ? -24.86182 -8.33164  20.01577  1.000 37.66801  ? 149 LEU B N   1 
ATOM   3601 C  CA  . LEU C 1 169 ? -23.48539 -8.73323  20.28641  1.000 34.74278  ? 149 LEU B CA  1 
ATOM   3602 C  C   . LEU C 1 169 ? -22.77104 -9.14738  19.00553  1.000 38.23931  ? 149 LEU B C   1 
ATOM   3603 O  O   . LEU C 1 169 ? -21.60792 -8.78723  18.79164  1.000 38.91914  ? 149 LEU B O   1 
ATOM   3604 C  CB  . LEU C 1 169 ? -23.46386 -9.86902  21.30960  1.000 38.81072  ? 149 LEU B CB  1 
ATOM   3605 C  CG  . LEU C 1 169 ? -22.09650 -10.43690 21.69410  1.000 37.94352  ? 149 LEU B CG  1 
ATOM   3606 C  CD1 . LEU C 1 169 ? -21.23363 -9.36663  22.33797  1.000 43.21630  ? 149 LEU B CD1 1 
ATOM   3607 C  CD2 . LEU C 1 169 ? -22.25673 -11.62845 22.62553  1.000 37.57136  ? 149 LEU B CD2 1 
ATOM   3608 N  N   . LEU C 1 170 ? -23.45204 -9.90133  18.13814  1.000 33.13257  ? 150 LEU B N   1 
ATOM   3609 C  CA  . LEU C 1 170 ? -22.86021 -10.26225 16.85362  1.000 36.45119  ? 150 LEU B CA  1 
ATOM   3610 C  C   . LEU C 1 170 ? -22.56916 -9.02308  16.01883  1.000 33.87527  ? 150 LEU B C   1 
ATOM   3611 O  O   . LEU C 1 170 ? -21.52051 -8.93472  15.37009  1.000 36.53543  ? 150 LEU B O   1 
ATOM   3612 C  CB  . LEU C 1 170 ? -23.78416 -11.21634 16.09576  1.000 27.26338  ? 150 LEU B CB  1 
ATOM   3613 C  CG  . LEU C 1 170 ? -23.92479 -12.62242 16.68365  1.000 32.44019  ? 150 LEU B CG  1 
ATOM   3614 C  CD1 . LEU C 1 170 ? -25.21567 -13.28526 16.22320  1.000 26.06080  ? 150 LEU B CD1 1 
ATOM   3615 C  CD2 . LEU C 1 170 ? -22.72183 -13.47927 16.32121  1.000 26.59216  ? 150 LEU B CD2 1 
ATOM   3616 N  N   . ASP C 1 171 ? -23.48154 -8.04852  16.03343  1.000 34.56968  ? 151 ASP B N   1 
ATOM   3617 C  CA  . ASP C 1 171 ? -23.25335 -6.81590  15.28410  1.000 38.69376  ? 151 ASP B CA  1 
ATOM   3618 C  C   . ASP C 1 171 ? -22.03937 -6.05585  15.81069  1.000 44.98115  ? 151 ASP B C   1 
ATOM   3619 O  O   . ASP C 1 171 ? -21.23615 -5.53570  15.02712  1.000 38.77947  ? 151 ASP B O   1 
ATOM   3620 C  CB  . ASP C 1 171 ? -24.49960 -5.93467  15.33640  1.000 39.17700  ? 151 ASP B CB  1 
ATOM   3621 C  CG  . ASP C 1 171 ? -24.29698 -4.60101  14.64922  1.000 43.66919  ? 151 ASP B CG  1 
ATOM   3622 O  OD1 . ASP C 1 171 ? -24.12765 -4.58764  13.41077  1.000 45.74806  ? 151 ASP B OD1 1 
ATOM   3623 O  OD2 . ASP C 1 171 ? -24.30441 -3.56590  15.34941  1.000 44.04690  ? 151 ASP B OD2 1 
ATOM   3624 N  N   . ILE C 1 172 ? -21.88540 -5.98562  17.13530  1.000 36.47072  ? 152 ILE B N   1 
ATOM   3625 C  CA  . ILE C 1 172 ? -20.77202 -5.24166  17.71812  1.000 35.31891  ? 152 ILE B CA  1 
ATOM   3626 C  C   . ILE C 1 172 ? -19.43764 -5.89866  17.38021  1.000 35.07540  ? 152 ILE B C   1 
ATOM   3627 O  O   . ILE C 1 172 ? -18.43111 -5.20896  17.17251  1.000 30.70821  ? 152 ILE B O   1 
ATOM   3628 C  CB  . ILE C 1 172 ? -20.97272 -5.10627  19.23950  1.000 33.53159  ? 152 ILE B CB  1 
ATOM   3629 C  CG1 . ILE C 1 172 ? -22.23986 -4.30502  19.53779  1.000 33.35781  ? 152 ILE B CG1 1 
ATOM   3630 C  CG2 . ILE C 1 172 ? -19.77014 -4.43801  19.88924  1.000 35.79247  ? 152 ILE B CG2 1 
ATOM   3631 C  CD1 . ILE C 1 172 ? -22.62225 -4.29350  20.99729  1.000 33.83407  ? 152 ILE B CD1 1 
ATOM   3632 N  N   . LEU C 1 173 ? -19.40365 -7.22721  17.29856  1.000 41.32992  ? 153 LEU B N   1 
ATOM   3633 C  CA  . LEU C 1 173 ? -18.16466 -7.94483  17.02300  1.000 37.93519  ? 153 LEU B CA  1 
ATOM   3634 C  C   . LEU C 1 173 ? -17.77159 -7.92466  15.55062  1.000 33.15154  ? 153 LEU B C   1 
ATOM   3635 O  O   . LEU C 1 173 ? -16.73541 -8.49825  15.19835  1.000 35.84199  ? 153 LEU B O   1 
ATOM   3636 C  CB  . LEU C 1 173 ? -18.27382 -9.39310  17.51214  1.000 38.78773  ? 153 LEU B CB  1 
ATOM   3637 C  CG  . LEU C 1 173 ? -17.84257 -9.69128  18.95333  1.000 43.12399  ? 153 LEU B CG  1 
ATOM   3638 C  CD1 . LEU C 1 173 ? -16.34572 -9.51200  19.11173  1.000 41.88620  ? 153 LEU B CD1 1 
ATOM   3639 C  CD2 . LEU C 1 173 ? -18.58173 -8.82239  19.95881  1.000 48.59447  ? 153 LEU B CD2 1 
ATOM   3640 N  N   . GLY C 1 174 ? -18.55513 -7.28495  14.68873  1.000 32.62664  ? 154 GLY B N   1 
ATOM   3641 C  CA  . GLY C 1 174 ? -18.20509 -7.15951  13.29001  1.000 33.10613  ? 154 GLY B CA  1 
ATOM   3642 C  C   . GLY C 1 174 ? -18.91607 -8.09799  12.34121  1.000 42.30066  ? 154 GLY B C   1 
ATOM   3643 O  O   . GLY C 1 174 ? -18.55073 -8.14435  11.16037  1.000 38.30078  ? 154 GLY B O   1 
ATOM   3644 N  N   . PHE C 1 175 ? -19.90570 -8.85299  12.81300  1.000 36.80558  ? 155 PHE B N   1 
ATOM   3645 C  CA  . PHE C 1 175 ? -20.69685 -9.69056  11.92136  1.000 38.51180  ? 155 PHE B CA  1 
ATOM   3646 C  C   . PHE C 1 175 ? -21.63975 -8.80961  11.11052  1.000 40.14987  ? 155 PHE B C   1 
ATOM   3647 O  O   . PHE C 1 175 ? -22.52056 -8.14719  11.67028  1.000 45.89697  ? 155 PHE B O   1 
ATOM   3648 C  CB  . PHE C 1 175 ? -21.47305 -10.73616 12.71929  1.000 37.89708  ? 155 PHE B CB  1 
ATOM   3649 C  CG  . PHE C 1 175 ? -20.62088 -11.86540 13.23242  1.000 37.58936  ? 155 PHE B CG  1 
ATOM   3650 C  CD1 . PHE C 1 175 ? -19.90025 -11.73304 14.40869  1.000 34.96848  ? 155 PHE B CD1 1 
ATOM   3651 C  CD2 . PHE C 1 175 ? -20.54250 -13.06064 12.53560  1.000 37.47174  ? 155 PHE B CD2 1 
ATOM   3652 C  CE1 . PHE C 1 175 ? -19.11503 -12.77116 14.87977  1.000 33.65807  ? 155 PHE B CE1 1 
ATOM   3653 C  CE2 . PHE C 1 175 ? -19.76123 -14.10289 13.00050  1.000 35.23266  ? 155 PHE B CE2 1 
ATOM   3654 C  CZ  . PHE C 1 175 ? -19.04607 -13.95801 14.17390  1.000 40.55368  ? 155 PHE B CZ  1 
ATOM   3655 N  N   . VAL C 1 176 ? -21.44968 -8.79324  9.79521   1.000 41.49786  ? 156 VAL B N   1 
ATOM   3656 C  CA  . VAL C 1 176 ? -22.18944 -7.90893  8.90423   1.000 48.35905  ? 156 VAL B CA  1 
ATOM   3657 C  C   . VAL C 1 176 ? -23.29794 -8.70075  8.22576   1.000 54.88464  ? 156 VAL B C   1 
ATOM   3658 O  O   . VAL C 1 176 ? -23.05758 -9.79121  7.69071   1.000 43.94093  ? 156 VAL B O   1 
ATOM   3659 C  CB  . VAL C 1 176 ? -21.25651 -7.26406  7.86456   1.000 51.25813  ? 156 VAL B CB  1 
ATOM   3660 C  CG1 . VAL C 1 176 ? -22.06318 -6.50389  6.82411   1.000 43.04694  ? 156 VAL B CG1 1 
ATOM   3661 C  CG2 . VAL C 1 176 ? -20.25687 -6.33951  8.55026   1.000 29.80776  ? 156 VAL B CG2 1 
ATOM   3662 N  N   . GLN C 1 177 ? -24.51288 -8.15688  8.25544   1.000 53.07106  ? 157 GLN B N   1 
ATOM   3663 C  CA  . GLN C 1 177 ? -25.63641 -8.70899  7.51097   1.000 58.68761  ? 157 GLN B CA  1 
ATOM   3664 C  C   . GLN C 1 177 ? -25.67548 -8.08128  6.12305   1.000 61.56088  ? 157 GLN B C   1 
ATOM   3665 O  O   . GLN C 1 177 ? -25.68390 -6.85230  5.99337   1.000 64.44246  ? 157 GLN B O   1 
ATOM   3666 C  CB  . GLN C 1 177 ? -26.95016 -8.45015  8.24925   1.000 48.58953  ? 157 GLN B CB  1 
ATOM   3667 C  CG  . GLN C 1 177 ? -28.18421 -8.94230  7.51620   1.000 54.69219  ? 157 GLN B CG  1 
ATOM   3668 C  CD  . GLN C 1 177 ? -29.45358 -8.70012  8.30535   1.000 56.35241  ? 157 GLN B CD  1 
ATOM   3669 O  OE1 . GLN C 1 177 ? -29.40808 -8.44036  9.50853   1.000 44.04808  ? 157 GLN B OE1 1 
ATOM   3670 N  NE2 . GLN C 1 177 ? -30.59582 -8.77965  7.63164   1.000 56.42177  ? 157 GLN B NE2 1 
ATOM   3671 N  N   . HIS C 1 178 ? -25.70611 -8.92364  5.08892   1.000 65.38883  ? 158 HIS B N   1 
ATOM   3672 C  CA  . HIS C 1 178 ? -25.66641 -8.44716  3.71158   1.000 69.12272  ? 158 HIS B CA  1 
ATOM   3673 C  C   . HIS C 1 178 ? -27.00622 -8.50364  2.99500   1.000 74.70594  ? 158 HIS B C   1 
ATOM   3674 O  O   . HIS C 1 178 ? -27.26484 -7.65504  2.13761   1.000 79.48593  ? 158 HIS B O   1 
ATOM   3675 C  CB  . HIS C 1 178 ? -24.63543 -9.24326  2.90302   1.000 63.07080  ? 158 HIS B CB  1 
ATOM   3676 C  CG  . HIS C 1 178 ? -23.22133 -8.97135  3.30382   1.000 69.10848  ? 158 HIS B CG  1 
ATOM   3677 N  ND1 . HIS C 1 178 ? -22.51942 -7.87852  2.84429   1.000 66.52279  ? 158 HIS B ND1 1 
ATOM   3678 C  CD2 . HIS C 1 178 ? -22.38089 -9.64123  4.12696   1.000 67.07558  ? 158 HIS B CD2 1 
ATOM   3679 C  CE1 . HIS C 1 178 ? -21.30504 -7.88917  3.36245   1.000 65.52883  ? 158 HIS B CE1 1 
ATOM   3680 N  NE2 . HIS C 1 178 ? -21.19538 -8.94783  4.14490   1.000 59.13755  ? 158 HIS B NE2 1 
ATOM   3681 N  N   . GLY C 1 179 ? -27.85742 -9.47682  3.31125   1.000 76.53554  ? 159 GLY B N   1 
ATOM   3682 C  CA  . GLY C 1 179 ? -29.16097 -9.56760  2.69831   1.000 67.81309  ? 159 GLY B CA  1 
ATOM   3683 C  C   . GLY C 1 179 ? -30.26729 -9.13358  3.63801   1.000 62.23272  ? 159 GLY B C   1 
ATOM   3684 O  O   . GLY C 1 179 ? -30.02274 -8.74656  4.78589   1.000 57.99982  ? 159 GLY B O   1 
ATOM   3685 N  N   . PRO C 1 180 ? -31.50887 -9.18317  3.16560   1.000 65.86623  ? 160 PRO B N   1 
ATOM   3686 C  CA  . PRO C 1 180 ? -32.64875 -8.85618  4.02687   1.000 62.08419  ? 160 PRO B CA  1 
ATOM   3687 C  C   . PRO C 1 180 ? -32.97074 -10.00497 4.97509   1.000 68.78285  ? 160 PRO B C   1 
ATOM   3688 O  O   . PRO C 1 180 ? -32.49891 -11.13097 4.82297   1.000 70.95105  ? 160 PRO B O   1 
ATOM   3689 C  CB  . PRO C 1 180 ? -33.78891 -8.62573  3.03085   1.000 61.80956  ? 160 PRO B CB  1 
ATOM   3690 C  CG  . PRO C 1 180 ? -33.42964 -9.48788  1.86588   1.000 63.26266  ? 160 PRO B CG  1 
ATOM   3691 C  CD  . PRO C 1 180 ? -31.92344 -9.46641  1.77963   1.000 63.16459  ? 160 PRO B CD  1 
ATOM   3692 N  N   . THR C 1 181 ? -33.79801 -9.69567  5.96932   1.000 68.87049  ? 161 THR B N   1 
ATOM   3693 C  CA  . THR C 1 181 ? -34.21879 -10.70217 6.93630   1.000 63.70996  ? 161 THR B CA  1 
ATOM   3694 C  C   . THR C 1 181 ? -35.22257 -11.65285 6.29454   1.000 72.40602  ? 161 THR B C   1 
ATOM   3695 O  O   . THR C 1 181 ? -36.16598 -11.21698 5.62682   1.000 79.28968  ? 161 THR B O   1 
ATOM   3696 C  CB  . THR C 1 181 ? -34.82953 -10.03494 8.17088   1.000 58.54844  ? 161 THR B CB  1 
ATOM   3697 O  OG1 . THR C 1 181 ? -33.87014 -9.14612  8.75719   1.000 63.45005  ? 161 THR B OG1 1 
ATOM   3698 C  CG2 . THR C 1 181 ? -35.23572 -11.07898 9.20242   1.000 52.99251  ? 161 THR B CG2 1 
ATOM   3699 N  N   . LEU C 1 182 ? -35.01282 -12.95250 6.48966   1.000 66.30801  ? 162 LEU B N   1 
ATOM   3700 C  CA  . LEU C 1 182 ? -35.84407 -13.98211 5.88315   1.000 65.87009  ? 162 LEU B CA  1 
ATOM   3701 C  C   . LEU C 1 182 ? -36.81468 -14.55899 6.90590   1.000 78.49914  ? 162 LEU B C   1 
ATOM   3702 O  O   . LEU C 1 182 ? -36.46361 -14.75045 8.07386   1.000 80.16052  ? 162 LEU B O   1 
ATOM   3703 C  CB  . LEU C 1 182 ? -34.97977 -15.10515 5.30164   1.000 70.86227  ? 162 LEU B CB  1 
ATOM   3704 C  CG  . LEU C 1 182 ? -33.87476 -14.68951 4.32822   1.000 74.17029  ? 162 LEU B CG  1 
ATOM   3705 C  CD1 . LEU C 1 182 ? -33.16452 -15.91369 3.76499   1.000 54.31151  ? 162 LEU B CD1 1 
ATOM   3706 C  CD2 . LEU C 1 182 ? -34.43106 -13.82077 3.20793   1.000 77.22913  ? 162 LEU B CD2 1 
ATOM   3707 N  N   . SER C 1 183 ? -38.03605 -14.83472 6.45732   1.000 89.25820  ? 163 SER B N   1 
ATOM   3708 C  CA  . SER C 1 183 ? -39.05476 -15.48457 7.26864   1.000 98.06479  ? 163 SER B CA  1 
ATOM   3709 C  C   . SER C 1 183 ? -39.38536 -16.84407 6.66801   1.000 98.01818  ? 163 SER B C   1 
ATOM   3710 O  O   . SER C 1 183 ? -39.47617 -16.98625 5.44441   1.000 100.46397 ? 163 SER B O   1 
ATOM   3711 C  CB  . SER C 1 183 ? -40.32029 -14.62636 7.36201   1.000 103.39032 ? 163 SER B CB  1 
ATOM   3712 O  OG  . SER C 1 183 ? -41.32174 -15.27186 8.13013   1.000 102.77974 ? 163 SER B OG  1 
ATOM   3713 N  N   . ASP C 1 184 ? -39.56168 -17.84407 7.53220   1.000 98.49366  ? 164 ASP B N   1 
ATOM   3714 C  CA  . ASP C 1 184 ? -39.81472 -19.21090 7.09719   1.000 106.93775 ? 164 ASP B CA  1 
ATOM   3715 C  C   . ASP C 1 184 ? -41.29510 -19.49051 6.85459   1.000 115.86891 ? 164 ASP B C   1 
ATOM   3716 O  O   . ASP C 1 184 ? -41.69134 -20.65929 6.77694   1.000 120.95155 ? 164 ASP B O   1 
ATOM   3717 C  CB  . ASP C 1 184 ? -39.25048 -20.20397 8.11726   1.000 98.90963  ? 164 ASP B CB  1 
ATOM   3718 C  CG  . ASP C 1 184 ? -40.01801 -20.20070 9.42667   1.000 100.56584 ? 164 ASP B CG  1 
ATOM   3719 O  OD1 . ASP C 1 184 ? -40.64979 -19.17323 9.75185   1.000 100.32549 ? 164 ASP B OD1 1 
ATOM   3720 O  OD2 . ASP C 1 184 ? -39.98524 -21.22991 10.13421  1.000 88.70289  ? 164 ASP B OD2 1 
ATOM   3721 N  N   . GLY C 1 185 ? -42.11761 -18.44910 6.73443   1.000 113.24173 ? 165 GLY B N   1 
ATOM   3722 C  CA  . GLY C 1 185 ? -43.53249 -18.59473 6.48485   1.000 111.14080 ? 165 GLY B CA  1 
ATOM   3723 C  C   . GLY C 1 185 ? -44.39209 -18.66446 7.73132   1.000 115.39285 ? 165 GLY B C   1 
ATOM   3724 O  O   . GLY C 1 185 ? -45.56517 -18.27990 7.68590   1.000 116.12375 ? 165 GLY B O   1 
ATOM   3725 N  N   . GLN C 1 186 ? -43.83911 -19.14776 8.84301   1.000 114.30519 ? 166 GLN B N   1 
ATOM   3726 C  CA  . GLN C 1 186 ? -44.58971 -19.23554 10.08879  1.000 120.04511 ? 166 GLN B CA  1 
ATOM   3727 C  C   . GLN C 1 186 ? -44.41047 -18.00372 10.96473  1.000 120.61131 ? 166 GLN B C   1 
ATOM   3728 O  O   . GLN C 1 186 ? -45.32778 -17.64585 11.71273  1.000 129.31227 ? 166 GLN B O   1 
ATOM   3729 C  CB  . GLN C 1 186 ? -44.17413 -20.49118 10.86462  1.000 115.67470 ? 166 GLN B CB  1 
ATOM   3730 C  CG  . GLN C 1 186 ? -45.17824 -20.95650 11.91466  1.000 123.64636 ? 166 GLN B CG  1 
ATOM   3731 C  CD  . GLN C 1 186 ? -45.00976 -20.25940 13.25274  1.000 126.99825 ? 166 GLN B CD  1 
ATOM   3732 O  OE1 . GLN C 1 186 ? -43.99901 -19.60276 13.50256  1.000 128.04307 ? 166 GLN B OE1 1 
ATOM   3733 N  NE2 . GLN C 1 186 ? -46.00397 -20.40132 14.12216  1.000 120.45955 ? 166 GLN B NE2 1 
ATOM   3734 N  N   . GLY C 1 187 ? -43.25689 -17.34535 10.88651  1.000 114.73868 ? 167 GLY B N   1 
ATOM   3735 C  CA  . GLY C 1 187 ? -42.99860 -16.17285 11.69814  1.000 110.08405 ? 167 GLY B CA  1 
ATOM   3736 C  C   . GLY C 1 187 ? -41.59624 -16.14790 12.26937  1.000 95.47636  ? 167 GLY B C   1 
ATOM   3737 O  O   . GLY C 1 187 ? -41.15503 -15.12819 12.80808  1.000 85.83780  ? 167 GLY B O   1 
ATOM   3738 N  N   . ARG C 1 188 ? -40.88761 -17.26957 12.15942  1.000 96.57438  ? 168 ARG B N   1 
ATOM   3739 C  CA  . ARG C 1 188 ? -39.51468 -17.36226 12.63981  1.000 84.78142  ? 168 ARG B CA  1 
ATOM   3740 C  C   . ARG C 1 188 ? -38.58711 -16.64412 11.66733  1.000 79.82588  ? 168 ARG B C   1 
ATOM   3741 O  O   . ARG C 1 188 ? -38.55725 -16.96519 10.47419  1.000 88.45633  ? 168 ARG B O   1 
ATOM   3742 C  CB  . ARG C 1 188 ? -39.10269 -18.82345 12.80377  1.000 85.09293  ? 168 ARG B CB  1 
ATOM   3743 C  CG  . ARG C 1 188 ? -37.64058 -19.01971 13.17539  1.000 80.16560  ? 168 ARG B CG  1 
ATOM   3744 C  CD  . ARG C 1 188 ? -37.34811 -20.47279 13.51416  1.000 92.98328  ? 168 ARG B CD  1 
ATOM   3745 N  NE  . ARG C 1 188 ? -38.03357 -20.89620 14.72936  1.000 89.62991  ? 168 ARG B NE  1 
ATOM   3746 C  CZ  . ARG C 1 188 ? -37.49975 -20.85599 15.94280  1.000 74.10335  ? 168 ARG B CZ  1 
ATOM   3747 N  NH1 . ARG C 1 188 ? -36.26446 -20.42512 16.14101  1.000 70.48019  ? 168 ARG B NH1 1 
ATOM   3748 N  NH2 . ARG C 1 188 ? -38.22317 -21.25854 16.98379  1.000 54.52776  ? 168 ARG B NH2 1 
ATOM   3749 N  N   . ARG C 1 189 ? -37.83332 -15.67689 12.17591  1.000 64.62759  ? 169 ARG B N   1 
ATOM   3750 C  CA  . ARG C 1 189 ? -36.94590 -14.86267 11.36212  1.000 64.60083  ? 169 ARG B CA  1 
ATOM   3751 C  C   . ARG C 1 189 ? -35.51964 -15.39395 11.43316  1.000 58.34531  ? 169 ARG B C   1 
ATOM   3752 O  O   . ARG C 1 189 ? -35.12149 -16.03232 12.41131  1.000 53.78305  ? 169 ARG B O   1 
ATOM   3753 C  CB  . ARG C 1 189 ? -36.98156 -13.40314 11.82009  1.000 61.74920  ? 169 ARG B CB  1 
ATOM   3754 C  CG  . ARG C 1 189 ? -38.36046 -12.76121 11.76489  1.000 59.86457  ? 169 ARG B CG  1 
ATOM   3755 C  CD  . ARG C 1 189 ? -38.39007 -11.48856 12.59231  1.000 57.10505  ? 169 ARG B CD  1 
ATOM   3756 N  NE  . ARG C 1 189 ? -37.42923 -10.50461 12.10748  1.000 57.07610  ? 169 ARG B NE  1 
ATOM   3757 C  CZ  . ARG C 1 189 ? -36.98562 -9.47592  12.81706  1.000 59.12187  ? 169 ARG B CZ  1 
ATOM   3758 N  NH1 . ARG C 1 189 ? -37.37690 -9.27675  14.06504  1.000 56.75837  ? 169 ARG B NH1 1 
ATOM   3759 N  NH2 . ARG C 1 189 ? -36.12262 -8.62932  12.26260  1.000 63.62271  ? 169 ARG B NH2 1 
ATOM   3760 N  N   . ARG C 1 190 ? -34.75264 -15.12638 10.37810  1.000 49.41863  ? 170 ARG B N   1 
ATOM   3761 C  CA  . ARG C 1 190 ? -33.36425 -15.55454 10.32052  1.000 49.71922  ? 170 ARG B CA  1 
ATOM   3762 C  C   . ARG C 1 190 ? -32.58359 -14.59637 9.43310   1.000 51.45039  ? 170 ARG B C   1 
ATOM   3763 O  O   . ARG C 1 190 ? -33.11095 -14.06029 8.45518   1.000 48.60667  ? 170 ARG B O   1 
ATOM   3764 C  CB  . ARG C 1 190 ? -33.23625 -16.99554 9.80538   1.000 45.79842  ? 170 ARG B CB  1 
ATOM   3765 C  CG  . ARG C 1 190 ? -33.62660 -17.18919 8.34726   1.000 56.00234  ? 170 ARG B CG  1 
ATOM   3766 C  CD  . ARG C 1 190 ? -33.57444 -18.66044 7.95571   1.000 61.56411  ? 170 ARG B CD  1 
ATOM   3767 N  NE  . ARG C 1 190 ? -33.61518 -18.84647 6.51018   1.000 52.62416  ? 170 ARG B NE  1 
ATOM   3768 C  CZ  . ARG C 1 190 ? -34.72887 -18.91607 5.79442   1.000 58.02470  ? 170 ARG B CZ  1 
ATOM   3769 N  NH1 . ARG C 1 190 ? -35.92089 -18.81936 6.35987   1.000 76.70845  ? 170 ARG B NH1 1 
ATOM   3770 N  NH2 . ARG C 1 190 ? -34.64445 -19.08457 4.47783   1.000 68.83784  ? 170 ARG B NH2 1 
ATOM   3771 N  N   . VAL C 1 191 ? -31.32249 -14.37561 9.79601   1.000 45.99259  ? 171 VAL B N   1 
ATOM   3772 C  CA  . VAL C 1 191 ? -30.41967 -13.51894 9.04077   1.000 41.03016  ? 171 VAL B CA  1 
ATOM   3773 C  C   . VAL C 1 191 ? -29.08702 -14.23614 8.88836   1.000 43.84558  ? 171 VAL B C   1 
ATOM   3774 O  O   . VAL C 1 191 ? -28.69972 -15.05625 9.72718   1.000 42.48124  ? 171 VAL B O   1 
ATOM   3775 C  CB  . VAL C 1 191 ? -30.22181 -12.14166 9.71241   1.000 49.07425  ? 171 VAL B CB  1 
ATOM   3776 C  CG1 . VAL C 1 191 ? -31.52293 -11.35201 9.71453   1.000 42.62459  ? 171 VAL B CG1 1 
ATOM   3777 C  CG2 . VAL C 1 191 ? -29.69315 -12.31159 11.13110  1.000 45.22624  ? 171 VAL B CG2 1 
ATOM   3778 N  N   . HIS C 1 192 ? -28.38242 -13.92201 7.80571   1.000 46.05719  ? 172 HIS B N   1 
ATOM   3779 C  CA  . HIS C 1 192 ? -27.09406 -14.52961 7.49734   1.000 44.19778  ? 172 HIS B CA  1 
ATOM   3780 C  C   . HIS C 1 192 ? -25.99624 -13.49527 7.70729   1.000 45.81403  ? 172 HIS B C   1 
ATOM   3781 O  O   . HIS C 1 192 ? -25.97467 -12.46242 7.02918   1.000 49.19674  ? 172 HIS B O   1 
ATOM   3782 C  CB  . HIS C 1 192 ? -27.07850 -15.06837 6.06735   1.000 44.11647  ? 172 HIS B CB  1 
ATOM   3783 C  CG  . HIS C 1 192 ? -28.01438 -16.21625 5.84980   1.000 44.67192  ? 172 HIS B CG  1 
ATOM   3784 N  ND1 . HIS C 1 192 ? -28.81311 -16.32597 4.73178   1.000 47.23688  ? 172 HIS B ND1 1 
ATOM   3785 C  CD2 . HIS C 1 192 ? -28.28017 -17.30483 6.61043   1.000 47.98784  ? 172 HIS B CD2 1 
ATOM   3786 C  CE1 . HIS C 1 192 ? -29.53202 -17.43128 4.81407   1.000 44.57429  ? 172 HIS B CE1 1 
ATOM   3787 N  NE2 . HIS C 1 192 ? -29.22668 -18.04407 5.94376   1.000 47.25892  ? 172 HIS B NE2 1 
ATOM   3788 N  N   . LEU C 1 193 ? -25.08988 -13.77814 8.64069   1.000 46.37200  ? 173 LEU B N   1 
ATOM   3789 C  CA  . LEU C 1 193 ? -24.05107 -12.85040 9.05851   1.000 41.17247  ? 173 LEU B CA  1 
ATOM   3790 C  C   . LEU C 1 193 ? -22.67686 -13.34200 8.62174   1.000 36.79896  ? 173 LEU B C   1 
ATOM   3791 O  O   . LEU C 1 193 ? -22.40512 -14.54812 8.59200   1.000 42.71820  ? 173 LEU B O   1 
ATOM   3792 C  CB  . LEU C 1 193 ? -24.06741 -12.66408 10.57906  1.000 37.51302  ? 173 LEU B CB  1 
ATOM   3793 C  CG  . LEU C 1 193 ? -25.41604 -12.25711 11.17513  1.000 42.02747  ? 173 LEU B CG  1 
ATOM   3794 C  CD1 . LEU C 1 193 ? -25.34807 -12.17969 12.69420  1.000 36.61248  ? 173 LEU B CD1 1 
ATOM   3795 C  CD2 . LEU C 1 193 ? -25.86444 -10.93500 10.58855  1.000 43.27085  ? 173 LEU B CD2 1 
ATOM   3796 N  N   . HIS C 1 194 ? -21.80590 -12.38038 8.31937   1.000 42.00870  ? 174 HIS B N   1 
ATOM   3797 C  CA  . HIS C 1 194 ? -20.45703 -12.62632 7.82835   1.000 39.94071  ? 174 HIS B CA  1 
ATOM   3798 C  C   . HIS C 1 194 ? -19.48106 -11.75522 8.60208   1.000 44.94283  ? 174 HIS B C   1 
ATOM   3799 O  O   . HIS C 1 194 ? -19.74528 -10.56761 8.81557   1.000 45.31633  ? 174 HIS B O   1 
ATOM   3800 C  CB  . HIS C 1 194 ? -20.36159 -12.31882 6.32637   1.000 42.49432  ? 174 HIS B CB  1 
ATOM   3801 C  CG  . HIS C 1 194 ? -18.96810 -12.05814 5.84275   1.000 45.80586  ? 174 HIS B CG  1 
ATOM   3802 N  ND1 . HIS C 1 194 ? -18.17130 -13.04530 5.30498   1.000 49.05714  ? 174 HIS B ND1 1 
ATOM   3803 C  CD2 . HIS C 1 194 ? -18.23387 -10.92013 5.80497   1.000 43.07356  ? 174 HIS B CD2 1 
ATOM   3804 C  CE1 . HIS C 1 194 ? -17.00548 -12.52803 4.96023   1.000 51.29638  ? 174 HIS B CE1 1 
ATOM   3805 N  NE2 . HIS C 1 194 ? -17.01627 -11.24088 5.25590   1.000 50.88932  ? 174 HIS B NE2 1 
ATOM   3806 N  N   . LYS C 1 195 ? -18.36074 -12.34033 9.02220   1.000 40.13801  ? 175 LYS B N   1 
ATOM   3807 C  CA  . LYS C 1 195 ? -17.26651 -11.57845 9.60767   1.000 38.49445  ? 175 LYS B CA  1 
ATOM   3808 C  C   . LYS C 1 195 ? -15.97318 -11.95202 8.90289   1.000 44.65329  ? 175 LYS B C   1 
ATOM   3809 O  O   . LYS C 1 195 ? -15.65385 -13.13740 8.77178   1.000 46.64968  ? 175 LYS B O   1 
ATOM   3810 C  CB  . LYS C 1 195 ? -17.13208 -11.82166 11.11580  1.000 39.60298  ? 175 LYS B CB  1 
ATOM   3811 C  CG  . LYS C 1 195 ? -15.94365 -11.07716 11.72207  1.000 45.18611  ? 175 LYS B CG  1 
ATOM   3812 C  CD  . LYS C 1 195 ? -15.83349 -11.24985 13.22655  1.000 44.76338  ? 175 LYS B CD  1 
ATOM   3813 C  CE  . LYS C 1 195 ? -14.60678 -10.51412 13.76224  1.000 54.05525  ? 175 LYS B CE  1 
ATOM   3814 N  NZ  . LYS C 1 195 ? -14.63746 -9.05124  13.46919  1.000 36.38008  ? 175 LYS B NZ  1 
ATOM   3815 N  N   . SER C 1 196 ? -15.23455 -10.94386 8.45024   1.000 48.45973  ? 176 SER B N   1 
ATOM   3816 C  CA  . SER C 1 196 ? -13.95325 -11.19453 7.80798   1.000 48.73568  ? 176 SER B CA  1 
ATOM   3817 C  C   . SER C 1 196 ? -12.93073 -11.66966 8.83177   1.000 44.09501  ? 176 SER B C   1 
ATOM   3818 O  O   . SER C 1 196 ? -12.92413 -11.22343 9.98223   1.000 48.33172  ? 176 SER B O   1 
ATOM   3819 C  CB  . SER C 1 196 ? -13.44950 -9.92982  7.11316   1.000 37.89251  ? 176 SER B CB  1 
ATOM   3820 O  OG  . SER C 1 196 ? -14.39277 -9.45915  6.16773   1.000 59.46526  ? 176 SER B OG  1 
ATOM   3821 N  N   . LEU C 1 197 ? -12.06652 -12.58358 8.40699   1.000 47.05031  ? 177 LEU B N   1 
ATOM   3822 C  CA  . LEU C 1 197 ? -11.00208 -13.11514 9.24116   1.000 53.49155  ? 177 LEU B CA  1 
ATOM   3823 C  C   . LEU C 1 197 ? -9.65489  -12.86160 8.57765   1.000 64.35135  ? 177 LEU B C   1 
ATOM   3824 O  O   . LEU C 1 197 ? -9.56991  -12.48279 7.40607   1.000 63.30389  ? 177 LEU B O   1 
ATOM   3825 C  CB  . LEU C 1 197 ? -11.19111 -14.61551 9.49671   1.000 55.35877  ? 177 LEU B CB  1 
ATOM   3826 C  CG  . LEU C 1 197 ? -12.46390 -15.06339 10.21702  1.000 50.54324  ? 177 LEU B CG  1 
ATOM   3827 C  CD1 . LEU C 1 197 ? -12.50956 -16.58019 10.29439  1.000 38.19856  ? 177 LEU B CD1 1 
ATOM   3828 C  CD2 . LEU C 1 197 ? -12.55222 -14.44843 11.60653  1.000 40.71750  ? 177 LEU B CD2 1 
ATOM   3829 N  N   . ARG C 1 198 ? -8.59355  -13.07477 9.34893   1.000 69.95463  ? 178 ARG B N   1 
ATOM   3830 C  CA  . ARG C 1 198 ? -7.23455  -12.97621 8.83087   1.000 79.37233  ? 178 ARG B CA  1 
ATOM   3831 C  C   . ARG C 1 198 ? -6.39859  -14.16607 9.29703   1.000 76.68889  ? 178 ARG B C   1 
ATOM   3832 O  O   . ARG C 1 198 ? -6.08976  -15.06883 8.51814   1.000 72.95541  ? 178 ARG B O   1 
ATOM   3833 C  CB  . ARG C 1 198 ? -6.58170  -11.66172 9.26754   1.000 84.57441  ? 178 ARG B CB  1 
ATOM   3834 C  CG  . ARG C 1 198 ? -7.22936  -10.41767 8.67421   1.000 89.96974  ? 178 ARG B CG  1 
ATOM   3835 C  CD  . ARG C 1 198 ? -7.08621  -10.38934 7.15925   1.000 86.96048  ? 178 ARG B CD  1 
ATOM   3836 N  NE  . ARG C 1 198 ? -7.80433  -9.27025  6.56059   1.000 88.74899  ? 178 ARG B NE  1 
ATOM   3837 C  CZ  . ARG C 1 198 ? -7.28654  -8.06547  6.36410   1.000 90.97055  ? 178 ARG B CZ  1 
ATOM   3838 N  NH1 . ARG C 1 198 ? -6.04065  -7.78396  6.70841   1.000 90.10479  ? 178 ARG B NH1 1 
ATOM   3839 N  NH2 . ARG C 1 198 ? -8.03817  -7.11900  5.80910   1.000 89.21979  ? 178 ARG B NH2 1 
ATOM   3840 N  N   . ALA D 1 34  ? -45.87636 13.28218  29.23872  1.000 41.57598  ? 14  ALA C N   1 
ATOM   3841 C  CA  . ALA D 1 34  ? -46.34813 12.31777  30.22417  1.000 45.53627  ? 14  ALA C CA  1 
ATOM   3842 C  C   . ALA D 1 34  ? -45.25755 11.96622  31.23845  1.000 47.15349  ? 14  ALA C C   1 
ATOM   3843 O  O   . ALA D 1 34  ? -44.25331 11.33667  30.89703  1.000 47.19235  ? 14  ALA C O   1 
ATOM   3844 C  CB  . ALA D 1 34  ? -46.85009 11.06050  29.53021  1.000 42.86982  ? 14  ALA C CB  1 
ATOM   3845 N  N   . TRP D 1 35  ? -45.46781 12.38116  32.48637  1.000 36.75535  ? 15  TRP C N   1 
ATOM   3846 C  CA  . TRP D 1 35  ? -44.57079 12.09365  33.60105  1.000 33.71803  ? 15  TRP C CA  1 
ATOM   3847 C  C   . TRP D 1 35  ? -45.33850 11.26919  34.62318  1.000 36.76319  ? 15  TRP C C   1 
ATOM   3848 O  O   . TRP D 1 35  ? -46.33883 11.74295  35.17370  1.000 42.82797  ? 15  TRP C O   1 
ATOM   3849 C  CB  . TRP D 1 35  ? -44.05362 13.38765  34.23600  1.000 36.22712  ? 15  TRP C CB  1 
ATOM   3850 C  CG  . TRP D 1 35  ? -43.21957 14.21411  33.31195  1.000 40.98978  ? 15  TRP C CG  1 
ATOM   3851 C  CD1 . TRP D 1 35  ? -43.66413 15.01850  32.30428  1.000 35.74468  ? 15  TRP C CD1 1 
ATOM   3852 C  CD2 . TRP D 1 35  ? -41.79182 14.32062  33.31152  1.000 40.57696  ? 15  TRP C CD2 1 
ATOM   3853 N  NE1 . TRP D 1 35  ? -42.60175 15.61793  31.67401  1.000 38.11551  ? 15  TRP C NE1 1 
ATOM   3854 C  CE2 . TRP D 1 35  ? -41.44056 15.20570  32.27366  1.000 40.57180  ? 15  TRP C CE2 1 
ATOM   3855 C  CE3 . TRP D 1 35  ? -40.77582 13.75196  34.08739  1.000 40.18814  ? 15  TRP C CE3 1 
ATOM   3856 C  CZ2 . TRP D 1 35  ? -40.11748 15.53644  31.99089  1.000 43.99355  ? 15  TRP C CZ2 1 
ATOM   3857 C  CZ3 . TRP D 1 35  ? -39.46062 14.08188  33.80454  1.000 41.44189  ? 15  TRP C CZ3 1 
ATOM   3858 C  CH2 . TRP D 1 35  ? -39.14445 14.96585  32.76523  1.000 43.59257  ? 15  TRP C CH2 1 
ATOM   3859 N  N   . GLN D 1 36  ? -44.88003 10.04412  34.88675  1.000 34.41124  ? 16  GLN C N   1 
ATOM   3860 C  CA  . GLN D 1 36  ? -45.64469 9.15477   35.75350  1.000 34.69027  ? 16  GLN C CA  1 
ATOM   3861 C  C   . GLN D 1 36  ? -44.79818 8.64147   36.90740  1.000 37.13048  ? 16  GLN C C   1 
ATOM   3862 O  O   . GLN D 1 36  ? -43.61798 8.33207   36.73721  1.000 37.89682  ? 16  GLN C O   1 
ATOM   3863 C  CB  . GLN D 1 36  ? -46.22193 7.97314   34.97193  1.000 37.03099  ? 16  GLN C CB  1 
ATOM   3864 C  CG  . GLN D 1 36  ? -47.47632 8.32217   34.19248  1.000 33.32951  ? 16  GLN C CG  1 
ATOM   3865 C  CD  . GLN D 1 36  ? -48.01047 7.15841   33.39141  1.000 34.20894  ? 16  GLN C CD  1 
ATOM   3866 O  OE1 . GLN D 1 36  ? -47.28190 6.53169   32.61929  1.000 37.69436  ? 16  GLN C OE1 1 
ATOM   3867 N  NE2 . GLN D 1 36  ? -49.28973 6.85591   33.57473  1.000 30.91656  ? 16  GLN C NE2 1 
ATOM   3868 N  N   . TRP D 1 37  ? -45.41259 8.54599   38.08211  1.000 36.50814  ? 17  TRP C N   1 
ATOM   3869 C  CA  . TRP D 1 37  ? -44.76996 7.97915   39.25782  1.000 35.20847  ? 17  TRP C CA  1 
ATOM   3870 C  C   . TRP D 1 37  ? -45.15186 6.51203   39.41846  1.000 34.25489  ? 17  TRP C C   1 
ATOM   3871 O  O   . TRP D 1 37  ? -46.23834 6.08599   39.01901  1.000 36.10513  ? 17  TRP C O   1 
ATOM   3872 C  CB  . TRP D 1 37  ? -45.15369 8.76186   40.51622  1.000 35.28312  ? 17  TRP C CB  1 
ATOM   3873 C  CG  . TRP D 1 37  ? -44.44174 10.06755  40.62590  1.000 36.66542  ? 17  TRP C CG  1 
ATOM   3874 C  CD1 . TRP D 1 37  ? -44.91838 11.29782  40.27282  1.000 34.20504  ? 17  TRP C CD1 1 
ATOM   3875 C  CD2 . TRP D 1 37  ? -43.10973 10.27613  41.10920  1.000 42.19001  ? 17  TRP C CD2 1 
ATOM   3876 N  NE1 . TRP D 1 37  ? -43.96573 12.25966  40.51383  1.000 31.26358  ? 17  TRP C NE1 1 
ATOM   3877 C  CE2 . TRP D 1 37  ? -42.84573 11.65757  41.02530  1.000 40.80752  ? 17  TRP C CE2 1 
ATOM   3878 C  CE3 . TRP D 1 37  ? -42.11615 9.42878   41.60724  1.000 34.67787  ? 17  TRP C CE3 1 
ATOM   3879 C  CZ2 . TRP D 1 37  ? -41.62952 12.20933  41.42065  1.000 33.31026  ? 17  TRP C CZ2 1 
ATOM   3880 C  CZ3 . TRP D 1 37  ? -40.91183 9.97841   42.00004  1.000 34.60289  ? 17  TRP C CZ3 1 
ATOM   3881 C  CH2 . TRP D 1 37  ? -40.67961 11.35595  41.90707  1.000 35.66022  ? 17  TRP C CH2 1 
ATOM   3882 N  N   . GLU D 1 38  ? -44.23844 5.73676   39.99797  1.000 31.49651  ? 18  GLU C N   1 
ATOM   3883 C  CA  . GLU D 1 38  ? -44.48851 4.32117   40.22170  1.000 38.05293  ? 18  GLU C CA  1 
ATOM   3884 C  C   . GLU D 1 38  ? -43.66477 3.85458   41.41213  1.000 31.59058  ? 18  GLU C C   1 
ATOM   3885 O  O   . GLU D 1 38  ? -42.59378 4.39444   41.69150  1.000 34.40882  ? 18  GLU C O   1 
ATOM   3886 C  CB  . GLU D 1 38  ? -44.14796 3.48913   38.97582  1.000 31.13511  ? 18  GLU C CB  1 
ATOM   3887 C  CG  . GLU D 1 38  ? -42.65533 3.39042   38.69279  1.000 34.45094  ? 18  GLU C CG  1 
ATOM   3888 C  CD  . GLU D 1 38  ? -42.34528 2.78578   37.33747  1.000 33.53743  ? 18  GLU C CD  1 
ATOM   3889 O  OE1 . GLU D 1 38  ? -42.91090 3.25614   36.32830  1.000 30.12283  ? 18  GLU C OE1 1 
ATOM   3890 O  OE2 . GLU D 1 38  ? -41.53422 1.83719   37.28268  1.000 42.54302  ? 18  GLU C OE2 1 
ATOM   3891 N  N   . VAL D 1 39  ? -44.17424 2.85447   42.12266  1.000 35.96180  ? 19  VAL C N   1 
ATOM   3892 C  CA  . VAL D 1 39  ? -43.37645 2.18907   43.14666  1.000 35.12671  ? 19  VAL C CA  1 
ATOM   3893 C  C   . VAL D 1 39  ? -42.44622 1.21635   42.43890  1.000 43.14389  ? 19  VAL C C   1 
ATOM   3894 O  O   . VAL D 1 39  ? -42.90139 0.25193   41.81469  1.000 40.42774  ? 19  VAL C O   1 
ATOM   3895 C  CB  . VAL D 1 39  ? -44.25844 1.46840   44.17419  1.000 37.30568  ? 19  VAL C CB  1 
ATOM   3896 C  CG1 . VAL D 1 39  ? -43.39494 0.65296   45.12559  1.000 30.69099  ? 19  VAL C CG1 1 
ATOM   3897 C  CG2 . VAL D 1 39  ? -45.08737 2.46795   44.94889  1.000 28.98176  ? 19  VAL C CG2 1 
ATOM   3898 N  N   . SER D 1 40  ? -41.14494 1.47440   42.52065  1.000 33.76022  ? 20  SER C N   1 
ATOM   3899 C  CA  . SER D 1 40  ? -40.19573 0.70536   41.73199  1.000 41.43537  ? 20  SER C CA  1 
ATOM   3900 C  C   . SER D 1 40  ? -40.16743 -0.75331  42.16984  1.000 39.69366  ? 20  SER C C   1 
ATOM   3901 O  O   . SER D 1 40  ? -40.15160 -1.06606  43.36392  1.000 45.38593  ? 20  SER C O   1 
ATOM   3902 C  CB  . SER D 1 40  ? -38.79704 1.30520   41.84143  1.000 40.90369  ? 20  SER C CB  1 
ATOM   3903 O  OG  . SER D 1 40  ? -37.90578 0.60616   40.99083  1.000 33.16756  ? 20  SER C OG  1 
ATOM   3904 N  N   . ARG D 1 41  ? -40.16957 -1.64645  41.18272  1.000 45.10509  ? 21  ARG C N   1 
ATOM   3905 C  CA  . ARG D 1 41  ? -40.04218 -3.07614  41.40591  1.000 49.27053  ? 21  ARG C CA  1 
ATOM   3906 C  C   . ARG D 1 41  ? -38.80931 -3.65251  40.72727  1.000 48.93361  ? 21  ARG C C   1 
ATOM   3907 O  O   . ARG D 1 41  ? -38.54444 -4.85387  40.86238  1.000 60.59042  ? 21  ARG C O   1 
ATOM   3908 C  CB  . ARG D 1 41  ? -41.29961 -3.80016  40.91017  1.000 50.84873  ? 21  ARG C CB  1 
ATOM   3909 C  CG  . ARG D 1 41  ? -42.58876 -3.12147  41.33976  1.000 60.84617  ? 21  ARG C CG  1 
ATOM   3910 C  CD  . ARG D 1 41  ? -43.78219 -3.70168  40.60907  1.000 52.30621  ? 21  ARG C CD  1 
ATOM   3911 N  NE  . ARG D 1 41  ? -43.85858 -5.14307  40.80408  1.000 68.12120  ? 21  ARG C NE  1 
ATOM   3912 C  CZ  . ARG D 1 41  ? -44.46219 -5.72721  41.82930  1.000 67.08137  ? 21  ARG C CZ  1 
ATOM   3913 N  NH1 . ARG D 1 41  ? -45.09408 -5.02164  42.75369  1.000 69.00133  ? 21  ARG C NH1 1 
ATOM   3914 N  NH2 . ARG D 1 41  ? -44.42458 -7.05171  41.93358  1.000 70.82710  ? 21  ARG C NH2 1 
ATOM   3915 N  N   . ASP D 1 42  ? -38.05755 -2.83287  39.99598  1.000 45.82423  ? 22  ASP C N   1 
ATOM   3916 C  CA  . ASP D 1 42  ? -36.81321 -3.24122  39.35488  1.000 43.24887  ? 22  ASP C CA  1 
ATOM   3917 C  C   . ASP D 1 42  ? -35.65535 -2.73846  40.21164  1.000 51.40567  ? 22  ASP C C   1 
ATOM   3918 O  O   . ASP D 1 42  ? -35.43627 -1.52801  40.32550  1.000 55.01320  ? 22  ASP C O   1 
ATOM   3919 C  CB  . ASP D 1 42  ? -36.73261 -2.69076  37.93286  1.000 39.91443  ? 22  ASP C CB  1 
ATOM   3920 C  CG  . ASP D 1 42  ? -35.65131 -3.35998  37.10581  1.000 52.41289  ? 22  ASP C CG  1 
ATOM   3921 O  OD1 . ASP D 1 42  ? -34.66543 -3.85850  37.69055  1.000 52.44189  ? 22  ASP C OD1 1 
ATOM   3922 O  OD2 . ASP D 1 42  ? -35.78809 -3.38557  35.86448  1.000 56.42807  ? 22  ASP C OD2 1 
ATOM   3923 N  N   . THR D 1 43  ? -34.91462 -3.67311  40.80775  1.000 51.32547  ? 23  THR C N   1 
ATOM   3924 C  CA  . THR D 1 43  ? -33.85489 -3.31006  41.74276  1.000 48.89193  ? 23  THR C CA  1 
ATOM   3925 C  C   . THR D 1 43  ? -32.61504 -2.79024  41.01724  1.000 44.74412  ? 23  THR C C   1 
ATOM   3926 O  O   . THR D 1 43  ? -32.00800 -1.79565  41.44290  1.000 44.75534  ? 23  THR C O   1 
ATOM   3927 C  CB  . THR D 1 43  ? -33.52309 -4.52071  42.61669  1.000 45.50729  ? 23  THR C CB  1 
ATOM   3928 O  OG1 . THR D 1 43  ? -34.50801 -4.65377  43.65046  1.000 52.89612  ? 23  THR C OG1 1 
ATOM   3929 C  CG2 . THR D 1 43  ? -32.17398 -4.37647  43.24495  1.000 52.77310  ? 23  THR C CG2 1 
ATOM   3930 N  N   . GLY D 1 44  ? -32.22779 -3.44527  39.92042  1.000 47.40534  ? 24  GLY C N   1 
ATOM   3931 C  CA  . GLY D 1 44  ? -31.07217 -2.99172  39.16674  1.000 38.31022  ? 24  GLY C CA  1 
ATOM   3932 C  C   . GLY D 1 44  ? -31.27694 -1.62253  38.55251  1.000 40.59992  ? 24  GLY C C   1 
ATOM   3933 O  O   . GLY D 1 44  ? -30.33268 -0.83899  38.44345  1.000 34.13813  ? 24  GLY C O   1 
ATOM   3934 N  N   . GLU D 1 45  ? -32.51464 -1.31391  38.15331  1.000 42.66312  ? 25  GLU C N   1 
ATOM   3935 C  CA  . GLU D 1 45  ? -32.83059 0.01282   37.63277  1.000 45.97672  ? 25  GLU C CA  1 
ATOM   3936 C  C   . GLU D 1 45  ? -32.57017 1.08540   38.68547  1.000 43.79637  ? 25  GLU C C   1 
ATOM   3937 O  O   . GLU D 1 45  ? -31.90696 2.09841   38.41575  1.000 34.86508  ? 25  GLU C O   1 
ATOM   3938 C  CB  . GLU D 1 45  ? -34.28854 0.03716   37.16669  1.000 41.74304  ? 25  GLU C CB  1 
ATOM   3939 C  CG  . GLU D 1 45  ? -34.65540 1.18657   36.24680  1.000 45.29693  ? 25  GLU C CG  1 
ATOM   3940 C  CD  . GLU D 1 45  ? -36.02287 0.99978   35.60745  1.000 45.35574  ? 25  GLU C CD  1 
ATOM   3941 O  OE1 . GLU D 1 45  ? -36.92987 0.45884   36.27393  1.000 37.71613  ? 25  GLU C OE1 1 
ATOM   3942 O  OE2 . GLU D 1 45  ? -36.18856 1.37843   34.42917  1.000 44.56986  ? 25  GLU C OE2 1 
ATOM   3943 N  N   . VAL D 1 46  ? -33.07672 0.86369   39.89993  1.000 38.18080  ? 26  VAL C N   1 
ATOM   3944 C  CA  . VAL D 1 46  ? -32.88178 1.81177   40.99061  1.000 37.64607  ? 26  VAL C CA  1 
ATOM   3945 C  C   . VAL D 1 46  ? -31.39878 1.99495   41.28030  1.000 40.10588  ? 26  VAL C C   1 
ATOM   3946 O  O   . VAL D 1 46  ? -30.90960 3.12419   41.42133  1.000 38.97154  ? 26  VAL C O   1 
ATOM   3947 C  CB  . VAL D 1 46  ? -33.64464 1.34293   42.24147  1.000 38.22773  ? 26  VAL C CB  1 
ATOM   3948 C  CG1 . VAL D 1 46  ? -33.22705 2.17016   43.45514  1.000 30.39949  ? 26  VAL C CG1 1 
ATOM   3949 C  CG2 . VAL D 1 46  ? -35.13092 1.45590   42.01593  1.000 30.74163  ? 26  VAL C CG2 1 
ATOM   3950 N  N   . HIS D 1 47  ? -30.66064 0.88774   41.38970  1.000 39.92803  ? 27  HIS C N   1 
ATOM   3951 C  CA  . HIS D 1 47  ? -29.25125 1.01576   41.74519  1.000 40.02649  ? 27  HIS C CA  1 
ATOM   3952 C  C   . HIS D 1 47  ? -28.46480 1.72627   40.65069  1.000 38.44683  ? 27  HIS C C   1 
ATOM   3953 O  O   . HIS D 1 47  ? -27.60806 2.57245   40.94696  1.000 39.45138  ? 27  HIS C O   1 
ATOM   3954 C  CB  . HIS D 1 47  ? -28.64693 -0.35380  42.04019  1.000 34.69517  ? 27  HIS C CB  1 
ATOM   3955 C  CG  . HIS D 1 47  ? -27.42625 -0.29149  42.90126  1.000 36.61389  ? 27  HIS C CG  1 
ATOM   3956 N  ND1 . HIS D 1 47  ? -27.49153 -0.20556  44.27551  1.000 36.77355  ? 27  HIS C ND1 1 
ATOM   3957 C  CD2 . HIS D 1 47  ? -26.11021 -0.27474  42.58394  1.000 32.51525  ? 27  HIS C CD2 1 
ATOM   3958 C  CE1 . HIS D 1 47  ? -26.26746 -0.15308  44.76872  1.000 36.53489  ? 27  HIS C CE1 1 
ATOM   3959 N  NE2 . HIS D 1 47  ? -25.41112 -0.19317  43.76346  1.000 38.14180  ? 27  HIS C NE2 1 
ATOM   3960 N  N   . ALA D 1 48  ? -28.73967 1.40114   39.38288  1.000 33.46305  ? 28  ALA C N   1 
ATOM   3961 C  CA  . ALA D 1 48  ? -28.04335 2.05994   38.28453  1.000 35.75172  ? 28  ALA C CA  1 
ATOM   3962 C  C   . ALA D 1 48  ? -28.29918 3.55687   38.30389  1.000 37.48939  ? 28  ALA C C   1 
ATOM   3963 O  O   . ALA D 1 48  ? -27.37439 4.36152   38.13736  1.000 35.39875  ? 28  ALA C O   1 
ATOM   3964 C  CB  . ALA D 1 48  ? -28.48096 1.45663   36.95007  1.000 36.31043  ? 28  ALA C CB  1 
ATOM   3965 N  N   . MET D 1 49  ? -29.55510 3.94923   38.51436  1.000 37.57702  ? 29  MET C N   1 
ATOM   3966 C  CA  . MET D 1 49  ? -29.89117 5.36650   38.53177  1.000 29.13906  ? 29  MET C CA  1 
ATOM   3967 C  C   . MET D 1 49  ? -29.19061 6.08271   39.68679  1.000 31.44021  ? 29  MET C C   1 
ATOM   3968 O  O   . MET D 1 49  ? -28.59788 7.15768   39.50575  1.000 29.10613  ? 29  MET C O   1 
ATOM   3969 C  CB  . MET D 1 49  ? -31.41357 5.51065   38.60009  1.000 32.03324  ? 29  MET C CB  1 
ATOM   3970 C  CG  . MET D 1 49  ? -31.90868 6.89583   38.88640  1.000 41.68359  ? 29  MET C CG  1 
ATOM   3971 S  SD  . MET D 1 49  ? -31.60654 7.96607   37.47069  1.000 64.44293  ? 29  MET C SD  1 
ATOM   3972 C  CE  . MET D 1 49  ? -30.10287 8.83039   37.94910  1.000 51.83238  ? 29  MET C CE  1 
ATOM   3973 N  N   . LEU D 1 50  ? -29.22734 5.48004   40.88414  1.000 31.79020  ? 30  LEU C N   1 
ATOM   3974 C  CA  . LEU D 1 50  ? -28.60112 6.09860   42.05150  1.000 31.08127  ? 30  LEU C CA  1 
ATOM   3975 C  C   . LEU D 1 50  ? -27.10562 6.29799   41.82713  1.000 35.52857  ? 30  LEU C C   1 
ATOM   3976 O  O   . LEU D 1 50  ? -26.56982 7.38730   42.06412  1.000 34.10563  ? 30  LEU C O   1 
ATOM   3977 C  CB  . LEU D 1 50  ? -28.85178 5.25714   43.30569  1.000 35.57561  ? 30  LEU C CB  1 
ATOM   3978 C  CG  . LEU D 1 50  ? -28.30234 5.88140   44.58303  1.000 38.54705  ? 30  LEU C CG  1 
ATOM   3979 C  CD1 . LEU D 1 50  ? -28.88981 7.27905   44.73823  1.000 31.55467  ? 30  LEU C CD1 1 
ATOM   3980 C  CD2 . LEU D 1 50  ? -28.64496 5.00701   45.76176  1.000 32.43347  ? 30  LEU C CD2 1 
ATOM   3981 N  N   . CYS D 1 51  ? -26.42201 5.26903   41.31338  1.000 38.09360  ? 31  CYS C N   1 
ATOM   3982 C  CA  . CYS D 1 51  ? -24.97703 5.38056   41.12059  1.000 33.59399  ? 31  CYS C CA  1 
ATOM   3983 C  C   . CYS D 1 51  ? -24.63096 6.36070   40.00384  1.000 36.27947  ? 31  CYS C C   1 
ATOM   3984 O  O   . CYS D 1 51  ? -23.64433 7.09971   40.11091  1.000 34.70729  ? 31  CYS C O   1 
ATOM   3985 C  CB  . CYS D 1 51  ? -24.36901 4.00150   40.85131  1.000 37.87674  ? 31  CYS C CB  1 
ATOM   3986 S  SG  . CYS D 1 51  ? -24.35367 2.94637   42.31244  1.000 37.30134  ? 31  CYS C SG  1 
ATOM   3987 N  N   . ALA D 1 52  ? -25.42530 6.38868   38.92750  1.000 34.56999  ? 32  ALA C N   1 
ATOM   3988 C  CA  . ALA D 1 52  ? -25.16995 7.34383   37.85416  1.000 34.16661  ? 32  ALA C CA  1 
ATOM   3989 C  C   . ALA D 1 52  ? -25.31625 8.78176   38.34524  1.000 35.70459  ? 32  ALA C C   1 
ATOM   3990 O  O   . ALA D 1 52  ? -24.47106 9.63851   38.04797  1.000 39.85706  ? 32  ALA C O   1 
ATOM   3991 C  CB  . ALA D 1 52  ? -26.10887 7.06453   36.67965  1.000 30.33746  ? 32  ALA C CB  1 
ATOM   3992 N  N   . CYS D 1 53  ? -26.38158 9.06704   39.10069  1.000 32.58456  ? 33  CYS C N   1 
ATOM   3993 C  CA  . CYS D 1 53  ? -26.56714 10.41755  39.62365  1.000 34.58229  ? 33  CYS C CA  1 
ATOM   3994 C  C   . CYS D 1 53  ? -25.45802 10.78439  40.59925  1.000 31.70898  ? 33  CYS C C   1 
ATOM   3995 O  O   . CYS D 1 53  ? -24.93003 11.90306  40.55493  1.000 35.72003  ? 33  CYS C O   1 
ATOM   3996 C  CB  . CYS D 1 53  ? -27.93546 10.54437  40.29362  1.000 32.83867  ? 33  CYS C CB  1 
ATOM   3997 S  SG  . CYS D 1 53  ? -28.31856 12.21047  40.91489  1.000 32.00623  ? 33  CYS C SG  1 
ATOM   3998 N  N   . ASP D 1 54  ? -25.09581 9.85616   41.49138  1.000 35.16418  ? 34  ASP C N   1 
ATOM   3999 C  CA  . ASP D 1 54  ? -23.98443 10.09608  42.40509  1.000 35.91368  ? 34  ASP C CA  1 
ATOM   4000 C  C   . ASP D 1 54  ? -22.71769 10.45102  41.63830  1.000 35.17408  ? 34  ASP C C   1 
ATOM   4001 O  O   . ASP D 1 54  ? -22.02938 11.42129  41.97180  1.000 30.77095  ? 34  ASP C O   1 
ATOM   4002 C  CB  . ASP D 1 54  ? -23.74380 8.86497   43.28197  1.000 33.44290  ? 34  ASP C CB  1 
ATOM   4003 C  CG  . ASP D 1 54  ? -24.85016 8.63165   44.28938  1.000 33.13349  ? 34  ASP C CG  1 
ATOM   4004 O  OD1 . ASP D 1 54  ? -25.58056 9.58754   44.61123  1.000 39.12317  ? 34  ASP C OD1 1 
ATOM   4005 O  OD2 . ASP D 1 54  ? -24.98518 7.48245   44.76051  1.000 41.16098  ? 34  ASP C OD2 1 
ATOM   4006 N  N   . ALA D 1 55  ? -22.40700 9.68202   40.59019  1.000 33.31974  ? 35  ALA C N   1 
ATOM   4007 C  CA  . ALA D 1 55  ? -21.18033 9.90693   39.83331  1.000 35.79276  ? 35  ALA C CA  1 
ATOM   4008 C  C   . ALA D 1 55  ? -21.19156 11.26864  39.15428  1.000 34.69564  ? 35  ALA C C   1 
ATOM   4009 O  O   . ALA D 1 55  ? -20.20476 12.01368  39.21469  1.000 37.78545  ? 35  ALA C O   1 
ATOM   4010 C  CB  . ALA D 1 55  ? -20.99289 8.79372   38.80340  1.000 36.00267  ? 35  ALA C CB  1 
ATOM   4011 N  N   . HIS D 1 56  ? -22.30092 11.61030  38.49410  1.000 36.98629  ? 36  HIS C N   1 
ATOM   4012 C  CA  . HIS D 1 56  ? -22.34653 12.87645  37.76991  1.000 37.22717  ? 36  HIS C CA  1 
ATOM   4013 C  C   . HIS D 1 56  ? -22.28549 14.06642  38.72231  1.000 38.18032  ? 36  HIS C C   1 
ATOM   4014 O  O   . HIS D 1 56  ? -21.55930 15.03519  38.46556  1.000 37.96832  ? 36  HIS C O   1 
ATOM   4015 C  CB  . HIS D 1 56  ? -23.59304 12.93686  36.89076  1.000 31.27690  ? 36  HIS C CB  1 
ATOM   4016 C  CG  . HIS D 1 56  ? -23.48332 12.11920  35.63952  1.000 45.29331  ? 36  HIS C CG  1 
ATOM   4017 N  ND1 . HIS D 1 56  ? -23.06499 12.64989  34.43606  1.000 34.97921  ? 36  HIS C ND1 1 
ATOM   4018 C  CD2 . HIS D 1 56  ? -23.72393 10.80643  35.40819  1.000 36.84762  ? 36  HIS C CD2 1 
ATOM   4019 C  CE1 . HIS D 1 56  ? -23.06243 11.70188  33.51599  1.000 29.01603  ? 36  HIS C CE1 1 
ATOM   4020 N  NE2 . HIS D 1 56  ? -23.45969 10.57438  34.07959  1.000 47.31161  ? 36  HIS C NE2 1 
ATOM   4021 N  N   . GLN D 1 57  ? -23.01212 14.01036  39.84152  1.000 38.72713  ? 37  GLN C N   1 
ATOM   4022 C  CA  . GLN D 1 57  ? -22.94957 15.12534  40.78074  1.000 37.40046  ? 37  GLN C CA  1 
ATOM   4023 C  C   . GLN D 1 57  ? -21.59029 15.21455  41.46387  1.000 36.91356  ? 37  GLN C C   1 
ATOM   4024 O  O   . GLN D 1 57  ? -21.10947 16.32201  41.73117  1.000 41.77673  ? 37  GLN C O   1 
ATOM   4025 C  CB  . GLN D 1 57  ? -24.07359 15.01537  41.80900  1.000 38.21563  ? 37  GLN C CB  1 
ATOM   4026 C  CG  . GLN D 1 57  ? -25.43394 15.41040  41.24727  1.000 44.21057  ? 37  GLN C CG  1 
ATOM   4027 C  CD  . GLN D 1 57  ? -26.53036 15.37662  42.29010  1.000 58.90970  ? 37  GLN C CD  1 
ATOM   4028 O  OE1 . GLN D 1 57  ? -26.47182 14.60114  43.24544  1.000 62.73026  ? 37  GLN C OE1 1 
ATOM   4029 N  NE2 . GLN D 1 57  ? -27.53914 16.22195  42.11420  1.000 48.96864  ? 37  GLN C NE2 1 
ATOM   4030 N  N   . ALA D 1 58  ? -20.94256 14.07552  41.72694  1.000 40.23604  ? 38  ALA C N   1 
ATOM   4031 C  CA  . ALA D 1 58  ? -19.61164 14.10524  42.32113  1.000 34.52798  ? 38  ALA C CA  1 
ATOM   4032 C  C   . ALA D 1 58  ? -18.59847 14.71886  41.36501  1.000 39.60107  ? 38  ALA C C   1 
ATOM   4033 O  O   . ALA D 1 58  ? -17.76192 15.53103  41.77633  1.000 44.19588  ? 38  ALA C O   1 
ATOM   4034 C  CB  . ALA D 1 58  ? -19.19112 12.69333  42.72582  1.000 37.62626  ? 38  ALA C CB  1 
ATOM   4035 N  N   . ALA D 1 59  ? -18.66712 14.35698  40.08115  1.000 36.26710  ? 39  ALA C N   1 
ATOM   4036 C  CA  . ALA D 1 59  ? -17.78420 14.97842  39.09877  1.000 35.03722  ? 39  ALA C CA  1 
ATOM   4037 C  C   . ALA D 1 59  ? -18.06388 16.47073  38.97206  1.000 38.41006  ? 39  ALA C C   1 
ATOM   4038 O  O   . ALA D 1 59  ? -17.13440 17.27304  38.82323  1.000 41.95960  ? 39  ALA C O   1 
ATOM   4039 C  CB  . ALA D 1 59  ? -17.93218 14.28961  37.74213  1.000 36.24220  ? 39  ALA C CB  1 
ATOM   4040 N  N   . ALA D 1 60  ? -19.34007 16.86455  39.03335  1.000 38.01135  ? 40  ALA C N   1 
ATOM   4041 C  CA  . ALA D 1 60  ? -19.67952 18.27384  38.86342  1.000 43.96670  ? 40  ALA C CA  1 
ATOM   4042 C  C   . ALA D 1 60  ? -19.26910 19.11455  40.06658  1.000 40.84051  ? 40  ALA C C   1 
ATOM   4043 O  O   . ALA D 1 60  ? -18.96342 20.30275  39.91241  1.000 40.88395  ? 40  ALA C O   1 
ATOM   4044 C  CB  . ALA D 1 60  ? -21.17789 18.42892  38.60521  1.000 36.72446  ? 40  ALA C CB  1 
ATOM   4045 N  N   . SER D 1 61  ? -19.26205 18.53274  41.26480  1.000 39.00921  ? 41  SER C N   1 
ATOM   4046 C  CA  . SER D 1 61  ? -18.98601 19.28639  42.48080  1.000 44.34138  ? 41  SER C CA  1 
ATOM   4047 C  C   . SER D 1 61  ? -17.58709 19.03935  43.03297  1.000 51.56200  ? 41  SER C C   1 
ATOM   4048 O  O   . SER D 1 61  ? -17.28164 19.49726  44.13855  1.000 48.22448  ? 41  SER C O   1 
ATOM   4049 C  CB  . SER D 1 61  ? -20.03073 18.96242  43.55029  1.000 42.88263  ? 41  SER C CB  1 
ATOM   4050 O  OG  . SER D 1 61  ? -19.93862 17.60887  43.95526  1.000 48.34478  ? 41  SER C OG  1 
ATOM   4051 N  N   . GLY D 1 62  ? -16.73193 18.33122  42.29886  1.000 41.04517  ? 42  GLY C N   1 
ATOM   4052 C  CA  . GLY D 1 62  ? -15.38694 18.07910  42.77495  1.000 40.76898  ? 42  GLY C CA  1 
ATOM   4053 C  C   . GLY D 1 62  ? -15.29359 17.19735  43.99877  1.000 47.36565  ? 42  GLY C C   1 
ATOM   4054 O  O   . GLY D 1 62  ? -14.30232 17.27336  44.72831  1.000 52.31640  ? 42  GLY C O   1 
ATOM   4055 N  N   . THR D 1 63  ? -16.29808 16.36553  44.25102  1.000 43.48947  ? 43  THR C N   1 
ATOM   4056 C  CA  . THR D 1 63  ? -16.30409 15.43125  45.36677  1.000 42.34037  ? 43  THR C CA  1 
ATOM   4057 C  C   . THR D 1 63  ? -16.28812 13.99735  44.84248  1.000 41.78304  ? 43  THR C C   1 
ATOM   4058 O  O   . THR D 1 63  ? -16.29946 13.74655  43.63329  1.000 40.19290  ? 43  THR C O   1 
ATOM   4059 C  CB  . THR D 1 63  ? -17.52005 15.67080  46.26558  1.000 51.17827  ? 43  THR C CB  1 
ATOM   4060 O  OG1 . THR D 1 63  ? -18.70935 15.71492  45.46492  1.000 44.16919  ? 43  THR C OG1 1 
ATOM   4061 C  CG2 . THR D 1 63  ? -17.37263 16.97510  47.02746  1.000 51.67189  ? 43  THR C CG2 1 
ATOM   4062 N  N   . SER D 1 64  ? -16.25851 13.04740  45.77228  1.000 41.34839  ? 44  SER C N   1 
ATOM   4063 C  CA  . SER D 1 64  ? -16.29087 11.62937  45.44723  1.000 49.06921  ? 44  SER C CA  1 
ATOM   4064 C  C   . SER D 1 64  ? -17.66483 11.06152  45.77694  1.000 45.70388  ? 44  SER C C   1 
ATOM   4065 O  O   . SER D 1 64  ? -18.24997 11.38779  46.81512  1.000 41.51595  ? 44  SER C O   1 
ATOM   4066 C  CB  . SER D 1 64  ? -15.20286 10.85984  46.20436  1.000 48.44636  ? 44  SER C CB  1 
ATOM   4067 O  OG  . SER D 1 64  ? -15.38936 10.94502  47.60561  1.000 48.25808  ? 44  SER C OG  1 
ATOM   4068 N  N   . ALA D 1 65  ? -18.17691 10.21922  44.88517  1.000 38.47663  ? 45  ALA C N   1 
ATOM   4069 C  CA  . ALA D 1 65  ? -19.50674 9.66273   45.07264  1.000 39.95047  ? 45  ALA C CA  1 
ATOM   4070 C  C   . ALA D 1 65  ? -19.51859 8.71795   46.27217  1.000 37.77814  ? 45  ALA C C   1 
ATOM   4071 O  O   . ALA D 1 65  ? -18.54249 7.99941   46.50877  1.000 42.29822  ? 45  ALA C O   1 
ATOM   4072 C  CB  . ALA D 1 65  ? -19.96319 8.92024   43.81694  1.000 34.55001  ? 45  ALA C CB  1 
ATOM   4073 N  N   . PRO D 1 66  ? -20.59961 8.69768   47.04642  1.000 44.56322  ? 46  PRO C N   1 
ATOM   4074 C  CA  . PRO D 1 66  ? -20.65997 7.79861   48.20115  1.000 38.34014  ? 46  PRO C CA  1 
ATOM   4075 C  C   . PRO D 1 66  ? -20.79488 6.34822   47.76691  1.000 49.74620  ? 46  PRO C C   1 
ATOM   4076 O  O   . PRO D 1 66  ? -21.26219 6.03199   46.66972  1.000 43.86343  ? 46  PRO C O   1 
ATOM   4077 C  CB  . PRO D 1 66  ? -21.90673 8.27166   48.95591  1.000 40.66438  ? 46  PRO C CB  1 
ATOM   4078 C  CG  . PRO D 1 66  ? -22.76651 8.87431   47.89803  1.000 38.17054  ? 46  PRO C CG  1 
ATOM   4079 C  CD  . PRO D 1 66  ? -21.82345 9.50690   46.90861  1.000 36.64545  ? 46  PRO C CD  1 
ATOM   4080 N  N   . ALA D 1 67  ? -20.36515 5.45809   48.65578  1.000 55.19419  ? 47  ALA C N   1 
ATOM   4081 C  CA  . ALA D 1 67  ? -20.46299 4.02689   48.40571  1.000 59.43957  ? 47  ALA C CA  1 
ATOM   4082 C  C   . ALA D 1 67  ? -21.89968 3.57391   48.63067  1.000 56.64143  ? 47  ALA C C   1 
ATOM   4083 O  O   . ALA D 1 67  ? -22.43917 3.72279   49.73247  1.000 62.60641  ? 47  ALA C O   1 
ATOM   4084 C  CB  . ALA D 1 67  ? -19.50296 3.25808   49.30954  1.000 52.59308  ? 47  ALA C CB  1 
ATOM   4085 N  N   . ARG D 1 68  ? -22.52109 3.03565   47.58731  1.000 48.86420  ? 48  ARG C N   1 
ATOM   4086 C  CA  . ARG D 1 68  ? -23.89869 2.56952   47.65080  1.000 53.25000  ? 48  ARG C CA  1 
ATOM   4087 C  C   . ARG D 1 68  ? -23.91804 1.05461   47.79950  1.000 54.50372  ? 48  ARG C C   1 
ATOM   4088 O  O   . ARG D 1 68  ? -23.24763 0.34322   47.04374  1.000 53.61259  ? 48  ARG C O   1 
ATOM   4089 C  CB  . ARG D 1 68  ? -24.67423 2.99218   46.40290  1.000 49.39581  ? 48  ARG C CB  1 
ATOM   4090 C  CG  . ARG D 1 68  ? -24.75644 4.49648   46.20575  1.000 46.93216  ? 48  ARG C CG  1 
ATOM   4091 C  CD  . ARG D 1 68  ? -25.45120 5.17213   47.37829  1.000 37.50119  ? 48  ARG C CD  1 
ATOM   4092 N  NE  . ARG D 1 68  ? -25.73691 6.57277   47.09447  1.000 41.39677  ? 48  ARG C NE  1 
ATOM   4093 C  CZ  . ARG D 1 68  ? -26.47027 7.36314   47.86626  1.000 32.99516  ? 48  ARG C CZ  1 
ATOM   4094 N  NH1 . ARG D 1 68  ? -27.02300 6.92013   48.98411  1.000 36.03535  ? 48  ARG C NH1 1 
ATOM   4095 N  NH2 . ARG D 1 68  ? -26.65249 8.63035   47.50768  1.000 25.71427  ? 48  ARG C NH2 1 
ATOM   4096 N  N   . ARG D 1 69  ? -24.68678 0.56774   48.77107  1.000 58.82346  ? 49  ARG C N   1 
ATOM   4097 C  CA  . ARG D 1 69  ? -24.77388 -0.85925  49.04848  1.000 45.76175  ? 49  ARG C CA  1 
ATOM   4098 C  C   . ARG D 1 69  ? -25.90075 -1.48943  48.23983  1.000 49.46383  ? 49  ARG C C   1 
ATOM   4099 O  O   . ARG D 1 69  ? -27.03412 -0.99731  48.24556  1.000 51.96928  ? 49  ARG C O   1 
ATOM   4100 C  CB  . ARG D 1 69  ? -24.99253 -1.10899  50.54063  1.000 48.17571  ? 49  ARG C CB  1 
ATOM   4101 C  CG  . ARG D 1 69  ? -23.78057 -1.68141  51.25950  1.000 61.15479  ? 49  ARG C CG  1 
ATOM   4102 C  CD  . ARG D 1 69  ? -24.06957 -1.87519  52.73842  1.000 64.59484  ? 49  ARG C CD  1 
ATOM   4103 N  NE  . ARG D 1 69  ? -25.19361 -2.77638  52.96231  1.000 62.99364  ? 49  ARG C NE  1 
ATOM   4104 C  CZ  . ARG D 1 69  ? -25.96511 -2.75641  54.04042  1.000 74.44815  ? 49  ARG C CZ  1 
ATOM   4105 N  NH1 . ARG D 1 69  ? -25.78197 -1.86951  55.00503  1.000 65.68962  ? 49  ARG C NH1 1 
ATOM   4106 N  NH2 . ARG D 1 69  ? -26.95088 -3.64245  54.14927  1.000 72.41105  ? 49  ARG C NH2 1 
ATOM   4107 N  N   . MET D 1 70  ? -25.57605 -2.58545  47.55247  1.000 45.57154  ? 50  MET C N   1 
ATOM   4108 C  CA  . MET D 1 70  ? -26.56749 -3.32341  46.77610  1.000 48.71062  ? 50  MET C CA  1 
ATOM   4109 C  C   . MET D 1 70  ? -27.70676 -3.82610  47.66022  1.000 54.15580  ? 50  MET C C   1 
ATOM   4110 O  O   . MET D 1 70  ? -28.88834 -3.73018  47.29136  1.000 53.72049  ? 50  MET C O   1 
ATOM   4111 C  CB  . MET D 1 70  ? -25.87194 -4.48529  46.06179  1.000 58.74496  ? 50  MET C CB  1 
ATOM   4112 C  CG  . MET D 1 70  ? -26.70792 -5.21845  45.03607  1.000 69.27412  ? 50  MET C CG  1 
ATOM   4113 S  SD  . MET D 1 70  ? -27.27160 -4.13191  43.72011  1.000 90.09985  ? 50  MET C SD  1 
ATOM   4114 C  CE  . MET D 1 70  ? -28.98045 -3.94798  44.19066  1.000 51.88718  ? 50  MET C CE  1 
ATOM   4115 N  N   . GLU D 1 71  ? -27.36863 -4.35812  48.83779  1.000 56.64743  ? 51  GLU C N   1 
ATOM   4116 C  CA  . GLU D 1 71  ? -28.38772 -4.85590  49.75386  1.000 56.51427  ? 51  GLU C CA  1 
ATOM   4117 C  C   . GLU D 1 71  ? -29.36007 -3.75920  50.17017  1.000 53.25402  ? 51  GLU C C   1 
ATOM   4118 O  O   . GLU D 1 71  ? -30.55205 -4.02756  50.34674  1.000 55.24662  ? 51  GLU C O   1 
ATOM   4119 C  CB  . GLU D 1 71  ? -27.72258 -5.47634  50.98228  1.000 58.03214  ? 51  GLU C CB  1 
ATOM   4120 C  CG  . GLU D 1 71  ? -28.70668 -5.89069  52.06555  1.000 74.45364  ? 51  GLU C CG  1 
ATOM   4121 C  CD  . GLU D 1 71  ? -28.16147 -6.96877  52.98109  1.000 81.89460  ? 51  GLU C CD  1 
ATOM   4122 O  OE1 . GLU D 1 71  ? -27.08262 -7.51456  52.67527  1.000 72.09198  ? 51  GLU C OE1 1 
ATOM   4123 O  OE2 . GLU D 1 71  ? -28.81837 -7.27471  54.00097  1.000 72.59378  ? 51  GLU C OE2 1 
ATOM   4124 N  N   . THR D 1 72  ? -28.88109 -2.51987  50.31517  1.000 49.63537  ? 52  THR C N   1 
ATOM   4125 C  CA  . THR D 1 72  ? -29.77929 -1.42152  50.66153  1.000 48.60422  ? 52  THR C CA  1 
ATOM   4126 C  C   . THR D 1 72  ? -30.79731 -1.18239  49.55449  1.000 43.66781  ? 52  THR C C   1 
ATOM   4127 O  O   . THR D 1 72  ? -31.98923 -0.99430  49.82642  1.000 40.76720  ? 52  THR C O   1 
ATOM   4128 C  CB  . THR D 1 72  ? -28.97930 -0.14598  50.94150  1.000 49.38799  ? 52  THR C CB  1 
ATOM   4129 O  OG1 . THR D 1 72  ? -27.90855 -0.43797  51.84652  1.000 56.81189  ? 52  THR C OG1 1 
ATOM   4130 C  CG2 . THR D 1 72  ? -29.87115 0.92630   51.55531  1.000 39.08866  ? 52  THR C CG2 1 
ATOM   4131 N  N   . THR D 1 73  ? -30.34333 -1.18629  48.29865  1.000 41.27815  ? 53  THR C N   1 
ATOM   4132 C  CA  . THR D 1 73  ? -31.26023 -1.02859  47.17371  1.000 45.61235  ? 53  THR C CA  1 
ATOM   4133 C  C   . THR D 1 73  ? -32.30159 -2.14067  47.16083  1.000 53.72743  ? 53  THR C C   1 
ATOM   4134 O  O   . THR D 1 73  ? -33.50232 -1.88455  46.98938  1.000 51.53132  ? 53  THR C O   1 
ATOM   4135 C  CB  . THR D 1 73  ? -30.47820 -1.00537  45.85724  1.000 47.09478  ? 53  THR C CB  1 
ATOM   4136 O  OG1 . THR D 1 73  ? -29.53925 0.07810   45.87463  1.000 44.95781  ? 53  THR C OG1 1 
ATOM   4137 C  CG2 . THR D 1 73  ? -31.41889 -0.83759  44.67263  1.000 47.25810  ? 53  THR C CG2 1 
ATOM   4138 N  N   . GLU D 1 74  ? -31.85724 -3.38706  47.35255  1.000 48.63890  ? 54  GLU C N   1 
ATOM   4139 C  CA  . GLU D 1 74  ? -32.79187 -4.51014  47.35143  1.000 45.24765  ? 54  GLU C CA  1 
ATOM   4140 C  C   . GLU D 1 74  ? -33.80781 -4.38672  48.48311  1.000 52.74837  ? 54  GLU C C   1 
ATOM   4141 O  O   . GLU D 1 74  ? -35.00923 -4.59127  48.27748  1.000 44.22340  ? 54  GLU C O   1 
ATOM   4142 C  CB  . GLU D 1 74  ? -32.02604 -5.83015  47.44432  1.000 52.47908  ? 54  GLU C CB  1 
ATOM   4143 C  CG  . GLU D 1 74  ? -31.91790 -6.55749  46.11455  1.000 59.49305  ? 54  GLU C CG  1 
ATOM   4144 C  CD  . GLU D 1 74  ? -30.57330 -7.23122  45.90765  1.000 66.59719  ? 54  GLU C CD  1 
ATOM   4145 O  OE1 . GLU D 1 74  ? -29.90642 -7.56479  46.90960  1.000 65.84042  ? 54  GLU C OE1 1 
ATOM   4146 O  OE2 . GLU D 1 74  ? -30.17904 -7.41709  44.73583  1.000 63.37203  ? 54  GLU C OE2 1 
ATOM   4147 N  N   . HIS D 1 75  ? -33.34342 -4.04896  49.68823  1.000 46.07715  ? 55  HIS C N   1 
ATOM   4148 C  CA  . HIS D 1 75  ? -34.25369 -3.85918  50.81397  1.000 42.15430  ? 55  HIS C CA  1 
ATOM   4149 C  C   . HIS D 1 75  ? -35.28357 -2.77963  50.50453  1.000 51.55941  ? 55  HIS C C   1 
ATOM   4150 O  O   . HIS D 1 75  ? -36.48882 -2.99483  50.67782  1.000 48.02461  ? 55  HIS C O   1 
ATOM   4151 C  CB  . HIS D 1 75  ? -33.45095 -3.51777  52.07668  1.000 47.07724  ? 55  HIS C CB  1 
ATOM   4152 C  CG  . HIS D 1 75  ? -34.27948 -3.31948  53.31535  1.000 55.79972  ? 55  HIS C CG  1 
ATOM   4153 N  ND1 . HIS D 1 75  ? -33.73885 -3.38858  54.58190  1.000 69.63700  ? 55  HIS C ND1 1 
ATOM   4154 C  CD2 . HIS D 1 75  ? -35.59384 -3.03778  53.48721  1.000 67.43371  ? 55  HIS C CD2 1 
ATOM   4155 C  CE1 . HIS D 1 75  ? -34.68354 -3.16431  55.47806  1.000 65.50890  ? 55  HIS C CE1 1 
ATOM   4156 N  NE2 . HIS D 1 75  ? -35.81904 -2.94824  54.83970  1.000 61.09573  ? 55  HIS C NE2 1 
ATOM   4157 N  N   . ARG D 1 76  ? -34.83046 -1.61377  50.02897  1.000 46.15953  ? 56  ARG C N   1 
ATOM   4158 C  CA  . ARG D 1 76  ? -35.75959 -0.51107  49.79682  1.000 47.14269  ? 56  ARG C CA  1 
ATOM   4159 C  C   . ARG D 1 76  ? -36.78385 -0.86171  48.72342  1.000 43.11401  ? 56  ARG C C   1 
ATOM   4160 O  O   . ARG D 1 76  ? -37.96653 -0.52449  48.85521  1.000 41.59806  ? 56  ARG C O   1 
ATOM   4161 C  CB  . ARG D 1 76  ? -35.00153 0.76158   49.41645  1.000 45.32381  ? 56  ARG C CB  1 
ATOM   4162 C  CG  . ARG D 1 76  ? -33.99981 1.24816   50.44825  1.000 44.86560  ? 56  ARG C CG  1 
ATOM   4163 C  CD  . ARG D 1 76  ? -34.60026 1.36541   51.83874  1.000 45.60261  ? 56  ARG C CD  1 
ATOM   4164 N  NE  . ARG D 1 76  ? -33.60448 1.83129   52.79637  1.000 48.14052  ? 56  ARG C NE  1 
ATOM   4165 C  CZ  . ARG D 1 76  ? -33.76337 1.82059   54.11243  1.000 48.84443  ? 56  ARG C CZ  1 
ATOM   4166 N  NH1 . ARG D 1 76  ? -34.87008 1.36068   54.67092  1.000 50.41704  ? 56  ARG C NH1 1 
ATOM   4167 N  NH2 . ARG D 1 76  ? -32.78577 2.28181   54.88815  1.000 57.62706  ? 56  ARG C NH2 1 
ATOM   4168 N  N   . VAL D 1 77  ? -36.35493 -1.53961  47.65536  1.000 44.61155  ? 57  VAL C N   1 
ATOM   4169 C  CA  . VAL D 1 77  ? -37.29296 -1.91502  46.60022  1.000 52.24813  ? 57  VAL C CA  1 
ATOM   4170 C  C   . VAL D 1 77  ? -38.29638 -2.94020  47.11709  1.000 50.61093  ? 57  VAL C C   1 
ATOM   4171 O  O   . VAL D 1 77  ? -39.51050 -2.79378  46.92977  1.000 47.80891  ? 57  VAL C O   1 
ATOM   4172 C  CB  . VAL D 1 77  ? -36.53709 -2.43592  45.36475  1.000 47.92022  ? 57  VAL C CB  1 
ATOM   4173 C  CG1 . VAL D 1 77  ? -37.51010 -3.06945  44.38358  1.000 34.77274  ? 57  VAL C CG1 1 
ATOM   4174 C  CG2 . VAL D 1 77  ? -35.77071 -1.30261  44.69655  1.000 40.98761  ? 57  VAL C CG2 1 
ATOM   4175 N  N   . ARG D 1 78  ? -37.80632 -3.98902  47.78420  1.000 50.54669  ? 58  ARG C N   1 
ATOM   4176 C  CA  . ARG D 1 78  ? -38.68937 -5.03877  48.28089  1.000 51.20281  ? 58  ARG C CA  1 
ATOM   4177 C  C   . ARG D 1 78  ? -39.64024 -4.54402  49.36360  1.000 46.14166  ? 58  ARG C C   1 
ATOM   4178 O  O   . ARG D 1 78  ? -40.64679 -5.20643  49.63560  1.000 54.79765  ? 58  ARG C O   1 
ATOM   4179 C  CB  . ARG D 1 78  ? -37.86471 -6.21077  48.81087  1.000 48.65199  ? 58  ARG C CB  1 
ATOM   4180 C  CG  . ARG D 1 78  ? -37.00708 -6.89348  47.75367  1.000 57.12018  ? 58  ARG C CG  1 
ATOM   4181 C  CD  . ARG D 1 78  ? -36.77554 -8.34031  48.12395  1.000 64.80587  ? 58  ARG C CD  1 
ATOM   4182 N  NE  . ARG D 1 78  ? -38.02860 -8.94950  48.55035  1.000 77.67004  ? 58  ARG C NE  1 
ATOM   4183 C  CZ  . ARG D 1 78  ? -38.93994 -9.44387  47.72375  1.000 71.39468  ? 58  ARG C CZ  1 
ATOM   4184 N  NH1 . ARG D 1 78  ? -38.74611 -9.46967  46.41416  1.000 68.72406  ? 58  ARG C NH1 1 
ATOM   4185 N  NH2 . ARG D 1 78  ? -40.07676 -9.91883  48.22254  1.000 60.00198  ? 58  ARG C NH2 1 
ATOM   4186 N  N   . SER D 1 79  ? -39.34912 -3.40495  49.98381  1.000 43.02907  ? 59  SER C N   1 
ATOM   4187 C  CA  . SER D 1 79  ? -40.23997 -2.80362  50.96432  1.000 39.23060  ? 59  SER C CA  1 
ATOM   4188 C  C   . SER D 1 79  ? -41.22720 -1.82910  50.34001  1.000 44.12351  ? 59  SER C C   1 
ATOM   4189 O  O   . SER D 1 79  ? -42.04976 -1.25725  51.06238  1.000 36.26533  ? 59  SER C O   1 
ATOM   4190 C  CB  . SER D 1 79  ? -39.42519 -2.08607  52.04238  1.000 38.11622  ? 59  SER C CB  1 
ATOM   4191 O  OG  . SER D 1 79  ? -38.50604 -2.97282  52.65379  1.000 54.25040  ? 59  SER C OG  1 
ATOM   4192 N  N   . GLY D 1 80  ? -41.16848 -1.63047  49.02493  1.000 43.29071  ? 60  GLY C N   1 
ATOM   4193 C  CA  . GLY D 1 80  ? -42.02465 -0.65656  48.37567  1.000 41.00692  ? 60  GLY C CA  1 
ATOM   4194 C  C   . GLY D 1 80  ? -41.74077 0.77383   48.77306  1.000 40.16660  ? 60  GLY C C   1 
ATOM   4195 O  O   . GLY D 1 80  ? -42.66055 1.59755   48.79305  1.000 32.41846  ? 60  GLY C O   1 
ATOM   4196 N  N   . SER D 1 81  ? -40.48469 1.09500   49.08665  1.000 38.51147  ? 61  SER C N   1 
ATOM   4197 C  CA  . SER D 1 81  ? -40.11535 2.41465   49.57963  1.000 41.22504  ? 61  SER C CA  1 
ATOM   4198 C  C   . SER D 1 81  ? -39.50456 3.31418   48.51363  1.000 37.27542  ? 61  SER C C   1 
ATOM   4199 O  O   . SER D 1 81  ? -39.26570 4.49459   48.78938  1.000 36.20437  ? 61  SER C O   1 
ATOM   4200 C  CB  . SER D 1 81  ? -39.13240 2.28372   50.74961  1.000 35.77693  ? 61  SER C CB  1 
ATOM   4201 O  OG  . SER D 1 81  ? -39.69729 1.52234   51.80128  1.000 45.12335  ? 61  SER C OG  1 
ATOM   4202 N  N   . VAL D 1 82  ? -39.25010 2.79900   47.31522  1.000 38.65868  ? 62  VAL C N   1 
ATOM   4203 C  CA  . VAL D 1 82  ? -38.61249 3.56463   46.25060  1.000 35.55461  ? 62  VAL C CA  1 
ATOM   4204 C  C   . VAL D 1 82  ? -39.68997 4.05273   45.29300  1.000 37.32731  ? 62  VAL C C   1 
ATOM   4205 O  O   . VAL D 1 82  ? -40.37609 3.24657   44.65230  1.000 37.09296  ? 62  VAL C O   1 
ATOM   4206 C  CB  . VAL D 1 82  ? -37.55655 2.72822   45.51239  1.000 34.09117  ? 62  VAL C CB  1 
ATOM   4207 C  CG1 . VAL D 1 82  ? -36.78866 3.59421   44.52409  1.000 31.18392  ? 62  VAL C CG1 1 
ATOM   4208 C  CG2 . VAL D 1 82  ? -36.61513 2.07334   46.50535  1.000 31.43280  ? 62  VAL C CG2 1 
ATOM   4209 N  N   . HIS D 1 83  ? -39.83838 5.37135   45.19627  1.000 35.77987  ? 63  HIS C N   1 
ATOM   4210 C  CA  . HIS D 1 83  ? -40.75454 5.99819   44.25365  1.000 32.21511  ? 63  HIS C CA  1 
ATOM   4211 C  C   . HIS D 1 83  ? -39.94164 6.51927   43.07547  1.000 31.02391  ? 63  HIS C C   1 
ATOM   4212 O  O   . HIS D 1 83  ? -39.00382 7.30273   43.26382  1.000 36.37216  ? 63  HIS C O   1 
ATOM   4213 C  CB  . HIS D 1 83  ? -41.53217 7.13266   44.91987  1.000 27.66191  ? 63  HIS C CB  1 
ATOM   4214 C  CG  . HIS D 1 83  ? -42.28014 6.71549   46.14869  1.000 35.16018  ? 63  HIS C CG  1 
ATOM   4215 N  ND1 . HIS D 1 83  ? -43.65703 6.71186   46.21631  1.000 33.83858  ? 63  HIS C ND1 1 
ATOM   4216 C  CD2 . HIS D 1 83  ? -41.84342 6.28897   47.35782  1.000 32.68862  ? 63  HIS C CD2 1 
ATOM   4217 C  CE1 . HIS D 1 83  ? -44.03617 6.30120   47.41341  1.000 36.87137  ? 63  HIS C CE1 1 
ATOM   4218 N  NE2 . HIS D 1 83  ? -42.95505 6.03765   48.12511  1.000 34.90524  ? 63  HIS C NE2 1 
ATOM   4219 N  N   . LEU D 1 84  ? -40.29826 6.08576   41.86833  1.000 28.19735  ? 64  LEU C N   1 
ATOM   4220 C  CA  . LEU D 1 84  ? -39.54519 6.38944   40.66112  1.000 32.88076  ? 64  LEU C CA  1 
ATOM   4221 C  C   . LEU D 1 84  ? -40.43181 7.13787   39.67688  1.000 38.98872  ? 64  LEU C C   1 
ATOM   4222 O  O   . LEU D 1 84  ? -41.55509 6.70702   39.38895  1.000 33.43461  ? 64  LEU C O   1 
ATOM   4223 C  CB  . LEU D 1 84  ? -38.99730 5.10771   40.02640  1.000 34.64221  ? 64  LEU C CB  1 
ATOM   4224 C  CG  . LEU D 1 84  ? -38.09290 5.25987   38.80291  1.000 28.80133  ? 64  LEU C CG  1 
ATOM   4225 C  CD1 . LEU D 1 84  ? -36.91054 4.31738   38.91830  1.000 28.32697  ? 64  LEU C CD1 1 
ATOM   4226 C  CD2 . LEU D 1 84  ? -38.86862 4.98507   37.52374  1.000 27.41090  ? 64  LEU C CD2 1 
ATOM   4227 N  N   . LEU D 1 85  ? -39.91988 8.25822   39.17409  1.000 36.25275  ? 65  LEU C N   1 
ATOM   4228 C  CA  . LEU D 1 85  ? -40.58066 9.07517   38.16800  1.000 38.40570  ? 65  LEU C CA  1 
ATOM   4229 C  C   . LEU D 1 85  ? -40.01743 8.71216   36.80110  1.000 32.82345  ? 65  LEU C C   1 
ATOM   4230 O  O   . LEU D 1 85  ? -38.81657 8.89772   36.55089  1.000 34.48807  ? 65  LEU C O   1 
ATOM   4231 C  CB  . LEU D 1 85  ? -40.37522 10.56282  38.45476  1.000 38.84783  ? 65  LEU C CB  1 
ATOM   4232 C  CG  . LEU D 1 85  ? -40.79416 11.52558  37.34031  1.000 41.12647  ? 65  LEU C CG  1 
ATOM   4233 C  CD1 . LEU D 1 85  ? -42.30299 11.48647  37.11752  1.000 29.43416  ? 65  LEU C CD1 1 
ATOM   4234 C  CD2 . LEU D 1 85  ? -40.31982 12.94376  37.63803  1.000 38.61024  ? 65  LEU C CD2 1 
ATOM   4235 N  N   . ARG D 1 86  ? -40.89229 8.21328   35.92907  1.000 30.46535  ? 66  ARG C N   1 
ATOM   4236 C  CA  . ARG D 1 86  ? -40.55808 7.75159   34.59302  1.000 31.59968  ? 66  ARG C CA  1 
ATOM   4237 C  C   . ARG D 1 86  ? -41.10885 8.72653   33.56017  1.000 34.23084  ? 66  ARG C C   1 
ATOM   4238 O  O   . ARG D 1 86  ? -42.20702 9.28274   33.72534  1.000 32.39200  ? 66  ARG C O   1 
ATOM   4239 C  CB  . ARG D 1 86  ? -41.12702 6.34552   34.34750  1.000 31.77969  ? 66  ARG C CB  1 
ATOM   4240 C  CG  . ARG D 1 86  ? -40.60955 5.64573   33.09599  1.000 33.91730  ? 66  ARG C CG  1 
ATOM   4241 C  CD  . ARG D 1 86  ? -41.12308 4.20485   32.99913  1.000 26.78337  ? 66  ARG C CD  1 
ATOM   4242 N  NE  . ARG D 1 86  ? -40.76957 3.41294   34.17145  1.000 23.79694  ? 66  ARG C NE  1 
ATOM   4243 C  CZ  . ARG D 1 86  ? -39.62363 2.76184   34.31906  1.000 27.96057  ? 66  ARG C CZ  1 
ATOM   4244 N  NH1 . ARG D 1 86  ? -38.69491 2.77327   33.37648  1.000 22.07488  ? 66  ARG C NH1 1 
ATOM   4245 N  NH2 . ARG D 1 86  ? -39.40070 2.08770   35.44365  1.000 24.67293  ? 66  ARG C NH2 1 
ATOM   4246 N  N   . HIS D 1 87  ? -40.32953 8.92677   32.49918  1.000 35.56183  ? 67  HIS C N   1 
ATOM   4247 C  CA  . HIS D 1 87  ? -40.67707 9.82176   31.40327  1.000 38.11954  ? 67  HIS C CA  1 
ATOM   4248 C  C   . HIS D 1 87  ? -40.17984 9.19884   30.10992  1.000 37.77935  ? 67  HIS C C   1 
ATOM   4249 O  O   . HIS D 1 87  ? -38.98698 8.90631   29.98409  1.000 38.96385  ? 67  HIS C O   1 
ATOM   4250 C  CB  . HIS D 1 87  ? -40.06256 11.21021  31.60802  1.000 38.59839  ? 67  HIS C CB  1 
ATOM   4251 C  CG  . HIS D 1 87  ? -40.29985 12.15189  30.46902  1.000 45.52791  ? 67  HIS C CG  1 
ATOM   4252 N  ND1 . HIS D 1 87  ? -41.54880 12.64635  30.15969  1.000 49.42378  ? 67  HIS C ND1 1 
ATOM   4253 C  CD2 . HIS D 1 87  ? -39.44729 12.69089  29.56535  1.000 52.16927  ? 67  HIS C CD2 1 
ATOM   4254 C  CE1 . HIS D 1 87  ? -41.45544 13.44989  29.11522  1.000 49.69345  ? 67  HIS C CE1 1 
ATOM   4255 N  NE2 . HIS D 1 87  ? -40.19109 13.49395  28.73511  1.000 58.50384  ? 67  HIS C NE2 1 
ATOM   4256 N  N   . ASP D 1 88  ? -41.09577 8.98344   29.16427  1.000 44.24826  ? 68  ASP C N   1 
ATOM   4257 C  CA  . ASP D 1 88  ? -40.76179 8.43814   27.84761  1.000 42.72175  ? 68  ASP C CA  1 
ATOM   4258 C  C   . ASP D 1 88  ? -40.12382 7.05594   27.96201  1.000 46.11094  ? 68  ASP C C   1 
ATOM   4259 O  O   . ASP D 1 88  ? -39.17396 6.72902   27.25002  1.000 44.10222  ? 68  ASP C O   1 
ATOM   4260 C  CB  . ASP D 1 88  ? -39.85566 9.39924   27.07071  1.000 47.73174  ? 68  ASP C CB  1 
ATOM   4261 C  CG  . ASP D 1 88  ? -39.99473 9.25188   25.56752  1.000 57.88257  ? 68  ASP C CG  1 
ATOM   4262 O  OD1 . ASP D 1 88  ? -41.11107 9.47086   25.05435  1.000 66.71862  ? 68  ASP C OD1 1 
ATOM   4263 O  OD2 . ASP D 1 88  ? -38.99039 8.92701   24.89910  1.000 62.38655  ? 68  ASP C OD2 1 
ATOM   4264 N  N   . GLY D 1 89  ? -40.64920 6.23649   28.87046  1.000 44.70041  ? 69  GLY C N   1 
ATOM   4265 C  CA  . GLY D 1 89  ? -40.15836 4.88708   29.05841  1.000 40.01889  ? 69  GLY C CA  1 
ATOM   4266 C  C   . GLY D 1 89  ? -38.93480 4.74706   29.93826  1.000 41.25374  ? 69  GLY C C   1 
ATOM   4267 O  O   . GLY D 1 89  ? -38.63974 3.62908   30.37904  1.000 35.49842  ? 69  GLY C O   1 
ATOM   4268 N  N   . ARG D 1 90  ? -38.21972 5.83589   30.22521  1.000 36.74137  ? 70  ARG C N   1 
ATOM   4269 C  CA  . ARG D 1 90  ? -36.96588 5.75592   30.95894  1.000 37.55671  ? 70  ARG C CA  1 
ATOM   4270 C  C   . ARG D 1 90  ? -37.06838 6.47772   32.29842  1.000 34.50205  ? 70  ARG C C   1 
ATOM   4271 O  O   . ARG D 1 90  ? -37.79744 7.46853   32.42297  1.000 34.33371  ? 70  ARG C O   1 
ATOM   4272 C  CB  . ARG D 1 90  ? -35.81928 6.35812   30.13568  1.000 38.45993  ? 70  ARG C CB  1 
ATOM   4273 C  CG  . ARG D 1 90  ? -35.73276 5.78381   28.73178  1.000 42.86833  ? 70  ARG C CG  1 
ATOM   4274 C  CD  . ARG D 1 90  ? -34.50174 6.25727   27.98155  1.000 53.54835  ? 70  ARG C CD  1 
ATOM   4275 N  NE  . ARG D 1 90  ? -34.52965 7.68871   27.71086  1.000 63.50828  ? 70  ARG C NE  1 
ATOM   4276 C  CZ  . ARG D 1 90  ? -33.83666 8.59204   28.38997  1.000 64.79895  ? 70  ARG C CZ  1 
ATOM   4277 N  NH1 . ARG D 1 90  ? -33.04847 8.24628   29.39502  1.000 53.66245  ? 70  ARG C NH1 1 
ATOM   4278 N  NH2 . ARG D 1 90  ? -33.93386 9.87383   28.04972  1.000 61.42590  ? 70  ARG C NH2 1 
ATOM   4279 N  N   . PRO D 1 91  ? -36.35378 6.00240   33.31999  1.000 39.16522  ? 71  PRO C N   1 
ATOM   4280 C  CA  . PRO D 1 91  ? -36.40514 6.67200   34.62743  1.000 33.69386  ? 71  PRO C CA  1 
ATOM   4281 C  C   . PRO D 1 91  ? -35.80596 8.06809   34.55184  1.000 32.64839  ? 71  PRO C C   1 
ATOM   4282 O  O   . PRO D 1 91  ? -34.68671 8.25689   34.07083  1.000 29.88223  ? 71  PRO C O   1 
ATOM   4283 C  CB  . PRO D 1 91  ? -35.57560 5.75502   35.53690  1.000 28.25671  ? 71  PRO C CB  1 
ATOM   4284 C  CG  . PRO D 1 91  ? -35.52289 4.44841   34.83206  1.000 27.59113  ? 71  PRO C CG  1 
ATOM   4285 C  CD  . PRO D 1 91  ? -35.54958 4.77010   33.36668  1.000 31.27186  ? 71  PRO C CD  1 
ATOM   4286 N  N   . ALA D 1 92  ? -36.56739 9.04966   35.02510  1.000 33.59283  ? 72  ALA C N   1 
ATOM   4287 C  CA  . ALA D 1 92  ? -36.08397 10.41949  35.10555  1.000 31.54057  ? 72  ALA C CA  1 
ATOM   4288 C  C   . ALA D 1 92  ? -35.66856 10.81576  36.51275  1.000 34.18702  ? 72  ALA C C   1 
ATOM   4289 O  O   . ALA D 1 92  ? -34.72218 11.59521  36.67034  1.000 31.98478  ? 72  ALA C O   1 
ATOM   4290 C  CB  . ALA D 1 92  ? -37.15158 11.39625  34.59966  1.000 30.89248  ? 72  ALA C CB  1 
ATOM   4291 N  N   . GLY D 1 93  ? -36.34698 10.30169  37.53652  1.000 28.17888  ? 73  GLY C N   1 
ATOM   4292 C  CA  . GLY D 1 93  ? -35.97150 10.64861  38.89570  1.000 27.03211  ? 73  GLY C CA  1 
ATOM   4293 C  C   . GLY D 1 93  ? -36.46294 9.59785   39.86386  1.000 33.64233  ? 73  GLY C C   1 
ATOM   4294 O  O   . GLY D 1 93  ? -37.14387 8.64739   39.47795  1.000 33.91805  ? 73  GLY C O   1 
ATOM   4295 N  N   . MET D 1 94  ? -36.11965 9.78150   41.13852  1.000 28.62758  ? 74  MET C N   1 
ATOM   4296 C  CA  . MET D 1 94  ? -36.60069 8.86952   42.17062  1.000 31.03381  ? 74  MET C CA  1 
ATOM   4297 C  C   . MET D 1 94  ? -36.23688 9.40938   43.54637  1.000 30.28120  ? 74  MET C C   1 
ATOM   4298 O  O   . MET D 1 94  ? -35.44305 10.34432  43.68886  1.000 28.67886  ? 74  MET C O   1 
ATOM   4299 C  CB  . MET D 1 94  ? -36.03575 7.45411   42.00058  1.000 39.71840  ? 74  MET C CB  1 
ATOM   4300 C  CG  . MET D 1 94  ? -34.55487 7.32968   42.31200  1.000 37.08657  ? 74  MET C CG  1 
ATOM   4301 S  SD  . MET D 1 94  ? -34.01745 5.60935   42.39664  1.000 37.62391  ? 74  MET C SD  1 
ATOM   4302 C  CE  . MET D 1 94  ? -32.24293 5.83080   42.45518  1.000 29.58537  ? 74  MET C CE  1 
ATOM   4303 N  N   . PHE D 1 95  ? -36.84145 8.79177   44.55896  1.000 28.86051  ? 75  PHE C N   1 
ATOM   4304 C  CA  . PHE D 1 95  ? -36.50243 9.02675   45.95653  1.000 35.64405  ? 75  PHE C CA  1 
ATOM   4305 C  C   . PHE D 1 95  ? -36.90553 7.79835   46.76088  1.000 38.95693  ? 75  PHE C C   1 
ATOM   4306 O  O   . PHE D 1 95  ? -37.60960 6.91417   46.26438  1.000 39.38298  ? 75  PHE C O   1 
ATOM   4307 C  CB  . PHE D 1 95  ? -37.17457 10.29677  46.50471  1.000 37.20631  ? 75  PHE C CB  1 
ATOM   4308 C  CG  . PHE D 1 95  ? -38.68004 10.25208  46.50218  1.000 32.26696  ? 75  PHE C CG  1 
ATOM   4309 C  CD1 . PHE D 1 95  ? -39.39768 10.68268  45.39749  1.000 36.74610  ? 75  PHE C CD1 1 
ATOM   4310 C  CD2 . PHE D 1 95  ? -39.37796 9.80401   47.61278  1.000 31.98101  ? 75  PHE C CD2 1 
ATOM   4311 C  CE1 . PHE D 1 95  ? -40.78225 10.65363  45.39475  1.000 35.73715  ? 75  PHE C CE1 1 
ATOM   4312 C  CE2 . PHE D 1 95  ? -40.76375 9.76999   47.61530  1.000 34.53808  ? 75  PHE C CE2 1 
ATOM   4313 C  CZ  . PHE D 1 95  ? -41.46555 10.19704  46.50586  1.000 31.32229  ? 75  PHE C CZ  1 
ATOM   4314 N  N   . THR D 1 96  ? -36.44176 7.74716   48.00878  1.000 35.68141  ? 76  THR C N   1 
ATOM   4315 C  CA  . THR D 1 96  ? -36.75650 6.66461   48.92814  1.000 38.81840  ? 76  THR C CA  1 
ATOM   4316 C  C   . THR D 1 96  ? -37.37108 7.26689   50.18043  1.000 39.75820  ? 76  THR C C   1 
ATOM   4317 O  O   . THR D 1 96  ? -36.78977 8.17201   50.78709  1.000 37.89256  ? 76  THR C O   1 
ATOM   4318 C  CB  . THR D 1 96  ? -35.50248 5.85021   49.28150  1.000 39.06318  ? 76  THR C CB  1 
ATOM   4319 O  OG1 . THR D 1 96  ? -35.01427 5.18301   48.11116  1.000 41.51974  ? 76  THR C OG1 1 
ATOM   4320 C  CG2 . THR D 1 96  ? -35.81273 4.81738   50.35907  1.000 34.56457  ? 76  THR C CG2 1 
ATOM   4321 N  N   . LEU D 1 97  ? -38.54354 6.76996   50.55888  1.000 40.33307  ? 77  LEU C N   1 
ATOM   4322 C  CA  . LEU D 1 97  ? -39.29554 7.29296   51.69134  1.000 38.22690  ? 77  LEU C CA  1 
ATOM   4323 C  C   . LEU D 1 97  ? -39.54117 6.15382   52.66820  1.000 40.20193  ? 77  LEU C C   1 
ATOM   4324 O  O   . LEU D 1 97  ? -40.23117 5.18473   52.33187  1.000 40.47558  ? 77  LEU C O   1 
ATOM   4325 C  CB  . LEU D 1 97  ? -40.61311 7.90886   51.22008  1.000 39.62010  ? 77  LEU C CB  1 
ATOM   4326 C  CG  . LEU D 1 97  ? -41.47842 8.66167   52.22643  1.000 47.38118  ? 77  LEU C CG  1 
ATOM   4327 C  CD1 . LEU D 1 97  ? -40.71174 9.82336   52.84191  1.000 40.54680  ? 77  LEU C CD1 1 
ATOM   4328 C  CD2 . LEU D 1 97  ? -42.73843 9.14951   51.53529  1.000 32.51707  ? 77  LEU C CD2 1 
ATOM   4329 N  N   . THR D 1 98  ? -38.96779 6.26095   53.86659  1.000 45.21024  ? 78  THR C N   1 
ATOM   4330 C  CA  . THR D 1 98  ? -39.05330 5.18828   54.85003  1.000 45.36100  ? 78  THR C CA  1 
ATOM   4331 C  C   . THR D 1 98  ? -39.51004 5.73419   56.19633  1.000 52.50408  ? 78  THR C C   1 
ATOM   4332 O  O   . THR D 1 98  ? -39.46466 6.93778   56.45420  1.000 50.57282  ? 78  THR C O   1 
ATOM   4333 C  CB  . THR D 1 98  ? -37.71053 4.45445   55.02031  1.000 45.39064  ? 78  THR C CB  1 
ATOM   4334 O  OG1 . THR D 1 98  ? -36.69369 5.38476   55.40905  1.000 46.31891  ? 78  THR C OG1 1 
ATOM   4335 C  CG2 . THR D 1 98  ? -37.29844 3.76918   53.71761  1.000 39.55668  ? 78  THR C CG2 1 
ATOM   4336 N  N   . TRP D 1 99  ? -39.97291 4.82793   57.05613  1.000 53.30014  ? 79  TRP C N   1 
ATOM   4337 C  CA  . TRP D 1 99  ? -40.34060 5.20943   58.41412  1.000 58.09214  ? 79  TRP C CA  1 
ATOM   4338 C  C   . TRP D 1 99  ? -39.17274 5.11952   59.38516  1.000 55.19383  ? 79  TRP C C   1 
ATOM   4339 O  O   . TRP D 1 99  ? -39.17738 5.80946   60.41106  1.000 58.67709  ? 79  TRP C O   1 
ATOM   4340 C  CB  . TRP D 1 99  ? -41.49373 4.33677   58.92319  1.000 56.15986  ? 79  TRP C CB  1 
ATOM   4341 C  CG  . TRP D 1 99  ? -42.83302 4.68624   58.34763  1.000 52.48994  ? 79  TRP C CG  1 
ATOM   4342 C  CD1 . TRP D 1 99  ? -43.49321 4.02997   57.34934  1.000 50.24922  ? 79  TRP C CD1 1 
ATOM   4343 C  CD2 . TRP D 1 99  ? -43.67776 5.77745   58.73786  1.000 53.84507  ? 79  TRP C CD2 1 
ATOM   4344 N  NE1 . TRP D 1 99  ? -44.69701 4.64392   57.09497  1.000 49.14204  ? 79  TRP C NE1 1 
ATOM   4345 C  CE2 . TRP D 1 99  ? -44.83376 5.71923   57.93346  1.000 47.75109  ? 79  TRP C CE2 1 
ATOM   4346 C  CE3 . TRP D 1 99  ? -43.56869 6.79687   59.68875  1.000 55.60956  ? 79  TRP C CE3 1 
ATOM   4347 C  CZ2 . TRP D 1 99  ? -45.87242 6.64170   58.05087  1.000 45.15362  ? 79  TRP C CZ2 1 
ATOM   4348 C  CZ3 . TRP D 1 99  ? -44.60025 7.70963   59.80308  1.000 57.01530  ? 79  TRP C CZ3 1 
ATOM   4349 C  CH2 . TRP D 1 99  ? -45.73662 7.62612   58.98913  1.000 58.05296  ? 79  TRP C CH2 1 
ATOM   4350 N  N   . ASP D 1 100 ? -38.18186 4.28370   59.08794  1.000 60.50120  ? 80  ASP C N   1 
ATOM   4351 C  CA  . ASP D 1 100 ? -37.00267 4.07776   59.90823  1.000 63.22326  ? 80  ASP C CA  1 
ATOM   4352 C  C   . ASP D 1 100 ? -35.80869 4.83339   59.33249  1.000 61.57800  ? 80  ASP C C   1 
ATOM   4353 O  O   . ASP D 1 100 ? -35.69061 4.98814   58.11289  1.000 53.75700  ? 80  ASP C O   1 
ATOM   4354 C  CB  . ASP D 1 100 ? -36.67868 2.58372   60.01138  1.000 57.71216  ? 80  ASP C CB  1 
ATOM   4355 C  CG  . ASP D 1 100 ? -36.58062 1.91328   58.65556  1.000 70.88055  ? 80  ASP C CG  1 
ATOM   4356 O  OD1 . ASP D 1 100 ? -35.83503 0.91720   58.53347  1.000 83.53625  ? 80  ASP C OD1 1 
ATOM   4357 O  OD2 . ASP D 1 100 ? -37.23954 2.38859   57.70557  1.000 71.39702  ? 80  ASP C OD2 1 
ATOM   4358 N  N   . PRO D 1 101 ? -34.91464 5.32068   60.18878  1.000 66.87092  ? 81  PRO C N   1 
ATOM   4359 C  CA  . PRO D 1 101 ? -33.81781 6.17644   59.71982  1.000 64.15977  ? 81  PRO C CA  1 
ATOM   4360 C  C   . PRO D 1 101 ? -32.83571 5.39981   58.86278  1.000 56.26117  ? 81  PRO C C   1 
ATOM   4361 O  O   . PRO D 1 101 ? -32.32393 4.35011   59.28088  1.000 56.20884  ? 81  PRO C O   1 
ATOM   4362 C  CB  . PRO D 1 101 ? -33.15853 6.65545   61.02405  1.000 60.26566  ? 81  PRO C CB  1 
ATOM   4363 C  CG  . PRO D 1 101 ? -34.17898 6.40935   62.09371  1.000 63.02464  ? 81  PRO C CG  1 
ATOM   4364 C  CD  . PRO D 1 101 ? -34.92669 5.19717   61.65562  1.000 55.58073  ? 81  PRO C CD  1 
ATOM   4365 N  N   . PRO D 1 102 ? -32.54505 5.88456   57.65309  1.000 56.71278  ? 82  PRO C N   1 
ATOM   4366 C  CA  . PRO D 1 102 ? -31.49024 5.27466   56.83623  1.000 53.14118  ? 82  PRO C CA  1 
ATOM   4367 C  C   . PRO D 1 102 ? -30.09153 5.76000   57.18006  1.000 57.24569  ? 82  PRO C C   1 
ATOM   4368 O  O   . PRO D 1 102 ? -29.13126 5.34565   56.51962  1.000 52.13788  ? 82  PRO C O   1 
ATOM   4369 C  CB  . PRO D 1 102 ? -31.88173 5.69837   55.41493  1.000 55.86345  ? 82  PRO C CB  1 
ATOM   4370 C  CG  . PRO D 1 102 ? -32.52061 7.03238   55.60692  1.000 55.48838  ? 82  PRO C CG  1 
ATOM   4371 C  CD  . PRO D 1 102 ? -33.23154 6.97781   56.94242  1.000 54.71707  ? 82  PRO C CD  1 
ATOM   4372 N  N   . PHE D 1 103 ? -29.95800 6.62979   58.18067  1.000 52.09674  ? 83  PHE C N   1 
ATOM   4373 C  CA  . PHE D 1 103 ? -28.66864 7.12892   58.62905  1.000 49.18610  ? 83  PHE C CA  1 
ATOM   4374 C  C   . PHE D 1 103 ? -28.67285 7.19274   60.14985  1.000 64.75930  ? 83  PHE C C   1 
ATOM   4375 O  O   . PHE D 1 103 ? -29.72052 7.09969   60.79645  1.000 65.68076  ? 83  PHE C O   1 
ATOM   4376 C  CB  . PHE D 1 103 ? -28.35180 8.50643   58.02968  1.000 57.09737  ? 83  PHE C CB  1 
ATOM   4377 C  CG  . PHE D 1 103 ? -29.44239 9.52567   58.22632  1.000 58.06276  ? 83  PHE C CG  1 
ATOM   4378 C  CD1 . PHE D 1 103 ? -29.50511 10.28368  59.38592  1.000 55.29303  ? 83  PHE C CD1 1 
ATOM   4379 C  CD2 . PHE D 1 103 ? -30.39760 9.73479   57.24556  1.000 58.88251  ? 83  PHE C CD2 1 
ATOM   4380 C  CE1 . PHE D 1 103 ? -30.50583 11.22346  59.56592  1.000 56.35102  ? 83  PHE C CE1 1 
ATOM   4381 C  CE2 . PHE D 1 103 ? -31.39810 10.67295  57.41960  1.000 49.97271  ? 83  PHE C CE2 1 
ATOM   4382 C  CZ  . PHE D 1 103 ? -31.45229 11.41770  58.58075  1.000 49.16730  ? 83  PHE C CZ  1 
ATOM   4383 N  N   . ALA D 1 104 ? -27.48402 7.35640   60.72220  1.000 62.81346  ? 84  ALA C N   1 
ATOM   4384 C  CA  . ALA D 1 104 ? -27.30939 7.41285   62.16747  1.000 60.92587  ? 84  ALA C CA  1 
ATOM   4385 C  C   . ALA D 1 104 ? -27.21720 8.86952   62.60379  1.000 61.83618  ? 84  ALA C C   1 
ATOM   4386 O  O   . ALA D 1 104 ? -26.34913 9.61031   62.12944  1.000 61.85972  ? 84  ALA C O   1 
ATOM   4387 C  CB  . ALA D 1 104 ? -26.06216 6.64085   62.59675  1.000 66.60522  ? 84  ALA C CB  1 
ATOM   4388 N  N   . ALA D 1 105 ? -28.11034 9.27541   63.50313  1.000 53.77355  ? 85  ALA C N   1 
ATOM   4389 C  CA  . ALA D 1 105 ? -28.10853 10.63232  64.02612  1.000 66.22077  ? 85  ALA C CA  1 
ATOM   4390 C  C   . ALA D 1 105 ? -28.61894 10.61053  65.45818  1.000 76.93264  ? 85  ALA C C   1 
ATOM   4391 O  O   . ALA D 1 105 ? -29.40455 9.73873   65.83882  1.000 78.08262  ? 85  ALA C O   1 
ATOM   4392 C  CB  . ALA D 1 105 ? -28.96377 11.57304  63.16898  1.000 62.88206  ? 85  ALA C CB  1 
ATOM   4393 N  N   . ASP D 1 106 ? -28.15964 11.57730  66.24905  1.000 89.28411  ? 86  ASP C N   1 
ATOM   4394 C  CA  . ASP D 1 106 ? -28.59296 11.67120  67.63603  1.000 102.41282 ? 86  ASP C CA  1 
ATOM   4395 C  C   . ASP D 1 106 ? -30.08673 11.95990  67.70862  1.000 105.91851 ? 86  ASP C C   1 
ATOM   4396 O  O   . ASP D 1 106 ? -30.64164 12.67249  66.86747  1.000 104.75186 ? 86  ASP C O   1 
ATOM   4397 C  CB  . ASP D 1 106 ? -27.80815 12.76126  68.36678  1.000 97.52588  ? 86  ASP C CB  1 
ATOM   4398 C  CG  . ASP D 1 106 ? -26.33981 12.42032  68.51546  1.000 88.83538  ? 86  ASP C CG  1 
ATOM   4399 O  OD1 . ASP D 1 106 ? -25.96337 11.26571  68.22072  1.000 82.91987  ? 86  ASP C OD1 1 
ATOM   4400 O  OD2 . ASP D 1 106 ? -25.56238 13.30818  68.92353  1.000 83.24936  ? 86  ASP C OD2 1 
ATOM   4401 N  N   . GLU D 1 107 ? -30.73941 11.39243  68.72641  1.000 112.08366 ? 87  GLU C N   1 
ATOM   4402 C  CA  . GLU D 1 107 ? -32.17837 11.57897  68.88154  1.000 115.00671 ? 87  GLU C CA  1 
ATOM   4403 C  C   . GLU D 1 107 ? -32.53365 13.04011  69.12002  1.000 113.29852 ? 87  GLU C C   1 
ATOM   4404 O  O   . GLU D 1 107 ? -33.58903 13.50314  68.67242  1.000 114.66514 ? 87  GLU C O   1 
ATOM   4405 C  CB  . GLU D 1 107 ? -32.70093 10.71096  70.02841  1.000 120.71123 ? 87  GLU C CB  1 
ATOM   4406 C  CG  . GLU D 1 107 ? -32.70959 9.20794   69.74925  1.000 120.22976 ? 87  GLU C CG  1 
ATOM   4407 C  CD  . GLU D 1 107 ? -31.34026 8.56013   69.88582  1.000 120.45813 ? 87  GLU C CD  1 
ATOM   4408 O  OE1 . GLU D 1 107 ? -30.37499 9.04360   69.25680  1.000 107.32949 ? 87  GLU C OE1 1 
ATOM   4409 O  OE2 . GLU D 1 107 ? -31.22914 7.56166   70.62831  1.000 119.85987 ? 87  GLU C OE2 1 
ATOM   4410 N  N   . GLY D 1 108 ? -31.67183 13.77957  69.81363  1.000 108.92192 ? 88  GLY C N   1 
ATOM   4411 C  CA  . GLY D 1 108 ? -31.89336 15.18440  70.07804  1.000 102.94366 ? 88  GLY C CA  1 
ATOM   4412 C  C   . GLY D 1 108 ? -31.51076 16.12951  68.96301  1.000 102.49605 ? 88  GLY C C   1 
ATOM   4413 O  O   . GLY D 1 108 ? -31.53934 17.34717  69.16260  1.000 99.09404  ? 88  GLY C O   1 
ATOM   4414 N  N   . ALA D 1 109 ? -31.15125 15.60842  67.78767  1.000 104.02877 ? 89  ALA C N   1 
ATOM   4415 C  CA  . ALA D 1 109 ? -30.76711 16.46605  66.67066  1.000 103.77382 ? 89  ALA C CA  1 
ATOM   4416 C  C   . ALA D 1 109 ? -31.98502 17.13363  66.03891  1.000 100.36035 ? 89  ALA C C   1 
ATOM   4417 O  O   . ALA D 1 109 ? -32.10103 18.36377  66.03524  1.000 97.86589  ? 89  ALA C O   1 
ATOM   4418 C  CB  . ALA D 1 109 ? -29.99437 15.65344  65.62853  1.000 94.79589  ? 89  ALA C CB  1 
ATOM   4419 N  N   . PHE D 1 110 ? -32.90574 16.33395  65.50563  1.000 88.82353  ? 90  PHE C N   1 
ATOM   4420 C  CA  . PHE D 1 110 ? -34.09604 16.85439  64.85474  1.000 77.41463  ? 90  PHE C CA  1 
ATOM   4421 C  C   . PHE D 1 110 ? -35.09343 17.38052  65.88176  1.000 81.61949  ? 90  PHE C C   1 
ATOM   4422 O  O   . PHE D 1 110 ? -35.07675 16.97103  67.04524  1.000 86.19702  ? 90  PHE C O   1 
ATOM   4423 C  CB  . PHE D 1 110 ? -34.75313 15.76550  64.01136  1.000 75.48074  ? 90  PHE C CB  1 
ATOM   4424 C  CG  . PHE D 1 110 ? -33.86569 15.21392  62.93406  1.000 76.84937  ? 90  PHE C CG  1 
ATOM   4425 C  CD1 . PHE D 1 110 ? -33.62420 15.93955  61.78000  1.000 70.69309  ? 90  PHE C CD1 1 
ATOM   4426 C  CD2 . PHE D 1 110 ? -33.28095 13.96485  63.07081  1.000 73.56162  ? 90  PHE C CD2 1 
ATOM   4427 C  CE1 . PHE D 1 110 ? -32.80886 15.43676  60.78808  1.000 65.57590  ? 90  PHE C CE1 1 
ATOM   4428 C  CE2 . PHE D 1 110 ? -32.46392 13.45504  62.07955  1.000 70.72182  ? 90  PHE C CE2 1 
ATOM   4429 C  CZ  . PHE D 1 110 ? -32.22807 14.19267  60.93678  1.000 66.36315  ? 90  PHE C CZ  1 
ATOM   4430 N  N   . PRO D 1 111 ? -35.97017 18.29722  65.47641  1.000 78.80803  ? 91  PRO C N   1 
ATOM   4431 C  CA  . PRO D 1 111 ? -37.04933 18.74474  66.36572  1.000 71.56343  ? 91  PRO C CA  1 
ATOM   4432 C  C   . PRO D 1 111 ? -37.97159 17.59230  66.71680  1.000 81.29088  ? 91  PRO C C   1 
ATOM   4433 O  O   . PRO D 1 111 ? -38.02259 16.58646  65.99204  1.000 80.77687  ? 91  PRO C O   1 
ATOM   4434 C  CB  . PRO D 1 111 ? -37.78197 19.80622  65.52971  1.000 71.13272  ? 91  PRO C CB  1 
ATOM   4435 C  CG  . PRO D 1 111 ? -36.79423 20.25012  64.52350  1.000 68.14699  ? 91  PRO C CG  1 
ATOM   4436 C  CD  . PRO D 1 111 ? -35.95246 19.05062  64.21095  1.000 76.71310  ? 91  PRO C CD  1 
ATOM   4437 N  N   . PRO D 1 112 ? -38.71252 17.69531  67.82024  1.000 86.58844  ? 92  PRO C N   1 
ATOM   4438 C  CA  . PRO D 1 112 ? -39.62150 16.60528  68.19535  1.000 83.55032  ? 92  PRO C CA  1 
ATOM   4439 C  C   . PRO D 1 112 ? -40.66463 16.35511  67.11502  1.000 78.30304  ? 92  PRO C C   1 
ATOM   4440 O  O   . PRO D 1 112 ? -41.19792 17.28751  66.51024  1.000 65.30226  ? 92  PRO C O   1 
ATOM   4441 C  CB  . PRO D 1 112 ? -40.26236 17.10837  69.49409  1.000 69.46560  ? 92  PRO C CB  1 
ATOM   4442 C  CG  . PRO D 1 112 ? -39.28663 18.10669  70.03652  1.000 74.74087  ? 92  PRO C CG  1 
ATOM   4443 C  CD  . PRO D 1 112 ? -38.67953 18.76542  68.83338  1.000 69.08222  ? 92  PRO C CD  1 
ATOM   4444 N  N   . ALA D 1 113 ? -40.94680 15.07642  66.87310  1.000 74.03917  ? 93  ALA C N   1 
ATOM   4445 C  CA  . ALA D 1 113 ? -41.91829 14.67269  65.86704  1.000 72.11539  ? 93  ALA C CA  1 
ATOM   4446 C  C   . ALA D 1 113 ? -42.59490 13.38939  66.32430  1.000 72.29706  ? 93  ALA C C   1 
ATOM   4447 O  O   . ALA D 1 113 ? -41.96216 12.54113  66.95993  1.000 72.57766  ? 93  ALA C O   1 
ATOM   4448 C  CB  . ALA D 1 113 ? -41.25831 14.47014  64.49700  1.000 74.79257  ? 93  ALA C CB  1 
ATOM   4449 N  N   . GLU D 1 114 ? -43.88192 13.25438  66.00004  1.000 75.92994  ? 94  GLU C N   1 
ATOM   4450 C  CA  . GLU D 1 114 ? -44.64246 12.07937  66.40871  1.000 74.75109  ? 94  GLU C CA  1 
ATOM   4451 C  C   . GLU D 1 114 ? -44.51483 10.94190  65.39918  1.000 78.87739  ? 94  GLU C C   1 
ATOM   4452 O  O   . GLU D 1 114 ? -44.23575 9.79991   65.77975  1.000 74.40751  ? 94  GLU C O   1 
ATOM   4453 C  CB  . GLU D 1 114 ? -46.11413 12.44635  66.61376  1.000 73.59249  ? 94  GLU C CB  1 
ATOM   4454 C  CG  . GLU D 1 114 ? -46.33322 13.66250  67.51069  1.000 82.96774  ? 94  GLU C CG  1 
ATOM   4455 C  CD  . GLU D 1 114 ? -45.67477 13.51632  68.87209  1.000 86.52780  ? 94  GLU C CD  1 
ATOM   4456 O  OE1 . GLU D 1 114 ? -45.57732 12.37491  69.37178  1.000 89.41957  ? 94  GLU C OE1 1 
ATOM   4457 O  OE2 . GLU D 1 114 ? -45.25437 14.54507  69.44203  1.000 83.39971  ? 94  GLU C OE2 1 
ATOM   4458 N  N   . ARG D 1 115 ? -44.70946 11.23507  64.11220  1.000 78.11889  ? 95  ARG C N   1 
ATOM   4459 C  CA  . ARG D 1 115 ? -44.57127 10.24958  63.03924  1.000 74.03803  ? 95  ARG C CA  1 
ATOM   4460 C  C   . ARG D 1 115 ? -43.67452 10.82631  61.95254  1.000 69.10633  ? 95  ARG C C   1 
ATOM   4461 O  O   . ARG D 1 115 ? -44.15564 11.24595  60.89097  1.000 69.59773  ? 95  ARG C O   1 
ATOM   4462 C  CB  . ARG D 1 115 ? -45.93636 9.85207   62.47625  1.000 74.31518  ? 95  ARG C CB  1 
ATOM   4463 C  CG  . ARG D 1 115 ? -46.75926 8.97126   63.40053  1.000 74.87892  ? 95  ARG C CG  1 
ATOM   4464 C  CD  . ARG D 1 115 ? -48.16649 8.78307   62.86219  1.000 69.59890  ? 95  ARG C CD  1 
ATOM   4465 N  NE  . ARG D 1 115 ? -48.89930 10.04303  62.83870  1.000 80.75058  ? 95  ARG C NE  1 
ATOM   4466 C  CZ  . ARG D 1 115 ? -50.11249 10.19829  62.32652  1.000 82.72461  ? 95  ARG C CZ  1 
ATOM   4467 N  NH1 . ARG D 1 115 ? -50.76225 9.18978   61.76873  1.000 75.55803  ? 95  ARG C NH1 1 
ATOM   4468 N  NH2 . ARG D 1 115 ? -50.68779 11.39656  62.37369  1.000 73.93297  ? 95  ARG C NH2 1 
ATOM   4469 N  N   . PRO D 1 116 ? -42.36241 10.86030  62.18099  1.000 70.04748  ? 96  PRO C N   1 
ATOM   4470 C  CA  . PRO D 1 116 ? -41.45449 11.39244  61.16097  1.000 62.04421  ? 96  PRO C CA  1 
ATOM   4471 C  C   . PRO D 1 116 ? -41.15046 10.36493  60.08301  1.000 61.98453  ? 96  PRO C C   1 
ATOM   4472 O  O   . PRO D 1 116 ? -41.01489 9.16793   60.34959  1.000 59.52846  ? 96  PRO C O   1 
ATOM   4473 C  CB  . PRO D 1 116 ? -40.19575 11.73922  61.96301  1.000 60.99046  ? 96  PRO C CB  1 
ATOM   4474 C  CG  . PRO D 1 116 ? -40.19315 10.74017  63.06868  1.000 61.99082  ? 96  PRO C CG  1 
ATOM   4475 C  CD  . PRO D 1 116 ? -41.64391 10.47427  63.41026  1.000 68.04616  ? 96  PRO C CD  1 
ATOM   4476 N  N   . LEU D 1 117 ? -41.05217 10.84932  58.85130  1.000 58.38351  ? 97  LEU C N   1 
ATOM   4477 C  CA  . LEU D 1 117 ? -40.61495 10.05082  57.71921  1.000 52.42344  ? 97  LEU C CA  1 
ATOM   4478 C  C   . LEU D 1 117 ? -39.24622 10.53180  57.25631  1.000 52.18376  ? 97  LEU C C   1 
ATOM   4479 O  O   . LEU D 1 117 ? -38.84846 11.67534  57.49822  1.000 55.82778  ? 97  LEU C O   1 
ATOM   4480 C  CB  . LEU D 1 117 ? -41.62803 10.11818  56.57201  1.000 51.84755  ? 97  LEU C CB  1 
ATOM   4481 C  CG  . LEU D 1 117 ? -42.84132 9.19451   56.70573  1.000 54.72199  ? 97  LEU C CG  1 
ATOM   4482 C  CD1 . LEU D 1 117 ? -44.08686 9.82959   56.10957  1.000 51.85045  ? 97  LEU C CD1 1 
ATOM   4483 C  CD2 . LEU D 1 117 ? -42.55246 7.86394   56.03203  1.000 47.12847  ? 97  LEU C CD2 1 
ATOM   4484 N  N   . TYR D 1 118 ? -38.52281 9.63987   56.58666  1.000 38.69879  ? 98  TYR C N   1 
ATOM   4485 C  CA  . TYR D 1 118 ? -37.14864 9.88456   56.18099  1.000 46.17407  ? 98  TYR C CA  1 
ATOM   4486 C  C   . TYR D 1 118 ? -37.04102 9.80957   54.66716  1.000 42.82759  ? 98  TYR C C   1 
ATOM   4487 O  O   . TYR D 1 118 ? -37.46597 8.81976   54.05499  1.000 48.61573  ? 98  TYR C O   1 
ATOM   4488 C  CB  . TYR D 1 118 ? -36.20019 8.87855   56.83563  1.000 47.14783  ? 98  TYR C CB  1 
ATOM   4489 C  CG  . TYR D 1 118 ? -36.04162 9.08637   58.32386  1.000 58.81995  ? 98  TYR C CG  1 
ATOM   4490 C  CD1 . TYR D 1 118 ? -36.97114 8.57626   59.22073  1.000 57.19422  ? 98  TYR C CD1 1 
ATOM   4491 C  CD2 . TYR D 1 118 ? -34.96441 9.80072   58.83153  1.000 58.70682  ? 98  TYR C CD2 1 
ATOM   4492 C  CE1 . TYR D 1 118 ? -36.83109 8.76849   60.58124  1.000 66.52712  ? 98  TYR C CE1 1 
ATOM   4493 C  CE2 . TYR D 1 118 ? -34.81489 9.99787   60.19026  1.000 60.48729  ? 98  TYR C CE2 1 
ATOM   4494 C  CZ  . TYR D 1 118 ? -35.75080 9.47993   61.06088  1.000 70.73029  ? 98  TYR C CZ  1 
ATOM   4495 O  OH  . TYR D 1 118 ? -35.60502 9.67457   62.41561  1.000 70.85445  ? 98  TYR C OH  1 
ATOM   4496 N  N   . LEU D 1 119 ? -36.47444 10.86117  54.08057  1.000 40.65903  ? 99  LEU C N   1 
ATOM   4497 C  CA  . LEU D 1 119 ? -36.19768 10.94823  52.65447  1.000 42.85425  ? 99  LEU C CA  1 
ATOM   4498 C  C   . LEU D 1 119 ? -34.72406 10.64788  52.41104  1.000 38.75701  ? 99  LEU C C   1 
ATOM   4499 O  O   . LEU D 1 119 ? -33.85053 11.26802  53.02802  1.000 43.37134  ? 99  LEU C O   1 
ATOM   4500 C  CB  . LEU D 1 119 ? -36.54925 12.34110  52.12719  1.000 39.80213  ? 99  LEU C CB  1 
ATOM   4501 C  CG  . LEU D 1 119 ? -36.04529 12.70508  50.73242  1.000 36.87695  ? 99  LEU C CG  1 
ATOM   4502 C  CD1 . LEU D 1 119 ? -36.85738 11.99610  49.66417  1.000 35.00821  ? 99  LEU C CD1 1 
ATOM   4503 C  CD2 . LEU D 1 119 ? -36.08535 14.20606  50.53857  1.000 35.12409  ? 99  LEU C CD2 1 
ATOM   4504 N  N   . SER D 1 120 ? -34.45102 9.70311   51.51271  1.000 35.63510  ? 100 SER C N   1 
ATOM   4505 C  CA  . SER D 1 120 ? -33.08536 9.31259   51.19490  1.000 36.65067  ? 100 SER C CA  1 
ATOM   4506 C  C   . SER D 1 120 ? -32.98545 8.99867   49.70908  1.000 35.17693  ? 100 SER C C   1 
ATOM   4507 O  O   . SER D 1 120 ? -33.99155 8.90425   49.00067  1.000 35.85467  ? 100 SER C O   1 
ATOM   4508 C  CB  . SER D 1 120 ? -32.62785 8.10923   52.03500  1.000 35.56134  ? 100 SER C CB  1 
ATOM   4509 O  OG  . SER D 1 120 ? -33.45772 6.97574   51.82494  1.000 34.90933  ? 100 SER C OG  1 
ATOM   4510 N  N   . ARG D 1 121 ? -31.74479 8.86062   49.24051  1.000 30.74453  ? 101 ARG C N   1 
ATOM   4511 C  CA  . ARG D 1 121 ? -31.45344 8.37893   47.88923  1.000 36.99710  ? 101 ARG C CA  1 
ATOM   4512 C  C   . ARG D 1 121 ? -32.22779 9.15260   46.82424  1.000 39.42180  ? 101 ARG C C   1 
ATOM   4513 O  O   . ARG D 1 121 ? -32.77653 8.57711   45.88054  1.000 27.70933  ? 101 ARG C O   1 
ATOM   4514 C  CB  . ARG D 1 121 ? -31.72973 6.88076   47.77834  1.000 35.97887  ? 101 ARG C CB  1 
ATOM   4515 C  CG  . ARG D 1 121 ? -30.85577 6.03506   48.68337  1.000 39.02112  ? 101 ARG C CG  1 
ATOM   4516 C  CD  . ARG D 1 121 ? -31.04244 4.56241   48.38953  1.000 37.53969  ? 101 ARG C CD  1 
ATOM   4517 N  NE  . ARG D 1 121 ? -29.82431 3.80789   48.65082  1.000 40.53074  ? 101 ARG C NE  1 
ATOM   4518 C  CZ  . ARG D 1 121 ? -29.52666 2.65129   48.07665  1.000 40.95504  ? 101 ARG C CZ  1 
ATOM   4519 N  NH1 . ARG D 1 121 ? -30.34328 2.08409   47.20517  1.000 39.30913  ? 101 ARG C NH1 1 
ATOM   4520 N  NH2 . ARG D 1 121 ? -28.37301 2.05856   48.37064  1.000 41.08043  ? 101 ARG C NH2 1 
ATOM   4521 N  N   . LEU D 1 122 ? -32.28677 10.47119  46.98516  1.000 37.44257  ? 102 LEU C N   1 
ATOM   4522 C  CA  . LEU D 1 122 ? -32.82949 11.31797  45.93428  1.000 33.81654  ? 102 LEU C CA  1 
ATOM   4523 C  C   . LEU D 1 122 ? -31.88182 11.29761  44.74272  1.000 33.22731  ? 102 LEU C C   1 
ATOM   4524 O  O   . LEU D 1 122 ? -30.67332 11.50060  44.89669  1.000 48.34179  ? 102 LEU C O   1 
ATOM   4525 C  CB  . LEU D 1 122 ? -33.01931 12.74617  46.43948  1.000 31.88843  ? 102 LEU C CB  1 
ATOM   4526 C  CG  . LEU D 1 122 ? -33.75787 13.68515  45.48008  1.000 38.20264  ? 102 LEU C CG  1 
ATOM   4527 C  CD1 . LEU D 1 122 ? -35.23144 13.82025  45.85738  1.000 35.50024  ? 102 LEU C CD1 1 
ATOM   4528 C  CD2 . LEU D 1 122 ? -33.08043 15.04897  45.40226  1.000 44.99598  ? 102 LEU C CD2 1 
ATOM   4529 N  N   . ALA D 1 123 ? -32.42292 11.03338  43.55630  1.000 32.43726  ? 103 ALA C N   1 
ATOM   4530 C  CA  . ALA D 1 123 ? -31.59294 10.87710  42.37160  1.000 30.06865  ? 103 ALA C CA  1 
ATOM   4531 C  C   . ALA D 1 123 ? -32.33769 11.39199  41.15059  1.000 28.06748  ? 103 ALA C C   1 
ATOM   4532 O  O   . ALA D 1 123 ? -33.53918 11.15661  41.00016  1.000 31.54596  ? 103 ALA C O   1 
ATOM   4533 C  CB  . ALA D 1 123 ? -31.18747 9.41141   42.16095  1.000 39.60066  ? 103 ALA C CB  1 
ATOM   4534 N  N   . VAL D 1 124 ? -31.61096 12.08819  40.28099  1.000 23.32467  ? 104 VAL C N   1 
ATOM   4535 C  CA  . VAL D 1 124 ? -32.14842 12.62907  39.03980  1.000 30.05060  ? 104 VAL C CA  1 
ATOM   4536 C  C   . VAL D 1 124 ? -31.26566 12.14986  37.89580  1.000 38.68127  ? 104 VAL C C   1 
ATOM   4537 O  O   . VAL D 1 124 ? -30.03706 12.11040  38.02748  1.000 38.38711  ? 104 VAL C O   1 
ATOM   4538 C  CB  . VAL D 1 124 ? -32.22149 14.17218  39.07502  1.000 28.63550  ? 104 VAL C CB  1 
ATOM   4539 C  CG1 . VAL D 1 124 ? -32.90064 14.70179  37.82987  1.000 34.61156  ? 104 VAL C CG1 1 
ATOM   4540 C  CG2 . VAL D 1 124 ? -32.95465 14.64648  40.32635  1.000 25.78291  ? 104 VAL C CG2 1 
ATOM   4541 N  N   . ALA D 1 125 ? -31.89316 11.77298  36.78272  1.000 32.65024  ? 105 ALA C N   1 
ATOM   4542 C  CA  . ALA D 1 125 ? -31.14826 11.26127  35.64100  1.000 30.65161  ? 105 ALA C CA  1 
ATOM   4543 C  C   . ALA D 1 125 ? -30.13099 12.29703  35.16808  1.000 33.38431  ? 105 ALA C C   1 
ATOM   4544 O  O   . ALA D 1 125 ? -30.41039 13.50139  35.20377  1.000 40.01862  ? 105 ALA C O   1 
ATOM   4545 C  CB  . ALA D 1 125 ? -32.09348 10.89578  34.49571  1.000 32.71743  ? 105 ALA C CB  1 
ATOM   4546 N  N   . PRO D 1 126 ? -28.94398 11.86775  34.72698  1.000 32.50095  ? 106 PRO C N   1 
ATOM   4547 C  CA  . PRO D 1 126 ? -27.91504 12.84234  34.32013  1.000 39.35742  ? 106 PRO C CA  1 
ATOM   4548 C  C   . PRO D 1 126 ? -28.37808 13.79563  33.23290  1.000 39.70811  ? 106 PRO C C   1 
ATOM   4549 O  O   . PRO D 1 126 ? -27.90995 14.93840  33.18081  1.000 39.94864  ? 106 PRO C O   1 
ATOM   4550 C  CB  . PRO D 1 126 ? -26.76322 11.94916  33.83557  1.000 34.83614  ? 106 PRO C CB  1 
ATOM   4551 C  CG  . PRO D 1 126 ? -26.96328 10.66201  34.56217  1.000 29.98889  ? 106 PRO C CG  1 
ATOM   4552 C  CD  . PRO D 1 126 ? -28.44616 10.48181  34.68227  1.000 32.31595  ? 106 PRO C CD  1 
ATOM   4553 N  N   . GLU D 1 127 ? -29.28923 13.36210  32.35933  1.000 38.96582  ? 107 GLU C N   1 
ATOM   4554 C  CA  . GLU D 1 127 ? -29.80697 14.25188  31.32459  1.000 44.22628  ? 107 GLU C CA  1 
ATOM   4555 C  C   . GLU D 1 127 ? -30.61283 15.39907  31.92273  1.000 51.16589  ? 107 GLU C C   1 
ATOM   4556 O  O   . GLU D 1 127 ? -30.72373 16.46575  31.30503  1.000 50.85431  ? 107 GLU C O   1 
ATOM   4557 C  CB  . GLU D 1 127 ? -30.66052 13.46285  30.33160  1.000 40.76979  ? 107 GLU C CB  1 
ATOM   4558 C  CG  . GLU D 1 127 ? -31.86015 12.79882  30.97427  1.000 48.95778  ? 107 GLU C CG  1 
ATOM   4559 C  CD  . GLU D 1 127 ? -32.46188 11.70080  30.11991  1.000 65.64379  ? 107 GLU C CD  1 
ATOM   4560 O  OE1 . GLU D 1 127 ? -32.91879 11.99193  28.99157  1.000 59.71363  ? 107 GLU C OE1 1 
ATOM   4561 O  OE2 . GLU D 1 127 ? -32.47922 10.53894  30.58036  1.000 55.82940  ? 107 GLU C OE2 1 
ATOM   4562 N  N   . TRP D 1 128 ? -31.19204 15.19828  33.10569  1.000 41.18806  ? 108 TRP C N   1 
ATOM   4563 C  CA  . TRP D 1 128 ? -32.00831 16.21278  33.75669  1.000 44.92666  ? 108 TRP C CA  1 
ATOM   4564 C  C   . TRP D 1 128 ? -31.24531 17.01030  34.80626  1.000 43.94555  ? 108 TRP C C   1 
ATOM   4565 O  O   . TRP D 1 128 ? -31.84581 17.83862  35.50009  1.000 49.47491  ? 108 TRP C O   1 
ATOM   4566 C  CB  . TRP D 1 128 ? -33.23766 15.56235  34.38717  1.000 41.12632  ? 108 TRP C CB  1 
ATOM   4567 C  CG  . TRP D 1 128 ? -34.04168 14.76178  33.41382  1.000 42.29324  ? 108 TRP C CG  1 
ATOM   4568 C  CD1 . TRP D 1 128 ? -34.20043 13.40695  33.40000  1.000 43.11286  ? 108 TRP C CD1 1 
ATOM   4569 C  CD2 . TRP D 1 128 ? -34.78785 15.26496  32.29831  1.000 45.35725  ? 108 TRP C CD2 1 
ATOM   4570 N  NE1 . TRP D 1 128 ? -35.00479 13.03534  32.34907  1.000 50.36013  ? 108 TRP C NE1 1 
ATOM   4571 C  CE2 . TRP D 1 128 ? -35.37890 14.15746  31.65800  1.000 43.34818  ? 108 TRP C CE2 1 
ATOM   4572 C  CE3 . TRP D 1 128 ? -35.01675 16.54439  31.78146  1.000 46.45057  ? 108 TRP C CE3 1 
ATOM   4573 C  CZ2 . TRP D 1 128 ? -36.18373 14.28953  30.52820  1.000 54.51845  ? 108 TRP C CZ2 1 
ATOM   4574 C  CZ3 . TRP D 1 128 ? -35.81742 16.67351  30.65959  1.000 51.93277  ? 108 TRP C CZ3 1 
ATOM   4575 C  CH2 . TRP D 1 128 ? -36.39101 15.55249  30.04550  1.000 54.27010  ? 108 TRP C CH2 1 
ATOM   4576 N  N   . LEU D 1 129 ? -29.94232 16.77367  34.94795  1.000 48.03945  ? 109 LEU C N   1 
ATOM   4577 C  CA  . LEU D 1 129 ? -29.10226 17.58885  35.82173  1.000 52.45729  ? 109 LEU C CA  1 
ATOM   4578 C  C   . LEU D 1 129 ? -28.55386 18.74732  34.99409  1.000 51.60216  ? 109 LEU C C   1 
ATOM   4579 O  O   . LEU D 1 129 ? -27.41813 18.74051  34.51404  1.000 53.88739  ? 109 LEU C O   1 
ATOM   4580 C  CB  . LEU D 1 129 ? -27.99694 16.74885  36.44783  1.000 47.09761  ? 109 LEU C CB  1 
ATOM   4581 C  CG  . LEU D 1 129 ? -28.47579 15.74303  37.49529  1.000 49.34475  ? 109 LEU C CG  1 
ATOM   4582 C  CD1 . LEU D 1 129 ? -27.29996 15.04046  38.15116  1.000 47.10851  ? 109 LEU C CD1 1 
ATOM   4583 C  CD2 . LEU D 1 129 ? -29.33897 16.44059  38.53556  1.000 50.87127  ? 109 LEU C CD2 1 
ATOM   4584 N  N   . THR D 1 130 ? -29.40088 19.75839  34.81736  1.000 64.86199  ? 110 THR C N   1 
ATOM   4585 C  CA  . THR D 1 130 ? -29.05977 20.94758  34.05296  1.000 69.56008  ? 110 THR C CA  1 
ATOM   4586 C  C   . THR D 1 130 ? -29.64627 22.16876  34.74474  1.000 64.75469  ? 110 THR C C   1 
ATOM   4587 O  O   . THR D 1 130 ? -30.70843 22.09629  35.36848  1.000 57.26792  ? 110 THR C O   1 
ATOM   4588 C  CB  . THR D 1 130 ? -29.57521 20.86585  32.60522  1.000 57.85209  ? 110 THR C CB  1 
ATOM   4589 O  OG1 . THR D 1 130 ? -30.89834 20.31406  32.59292  1.000 57.20195  ? 110 THR C OG1 1 
ATOM   4590 C  CG2 . THR D 1 130 ? -28.65725 20.00085  31.75239  1.000 50.71959  ? 110 THR C CG2 1 
ATOM   4591 N  N   . GLY D 1 131 ? -28.93821 23.29093  34.63431  1.000 70.88635  ? 111 GLY C N   1 
ATOM   4592 C  CA  . GLY D 1 131 ? -29.39994 24.53793  35.21272  1.000 66.97017  ? 111 GLY C CA  1 
ATOM   4593 C  C   . GLY D 1 131 ? -30.73900 24.97977  34.66002  1.000 69.85899  ? 111 GLY C C   1 
ATOM   4594 O  O   . GLY D 1 131 ? -30.82801 25.43497  33.51558  1.000 70.64496  ? 111 GLY C O   1 
ATOM   4595 N  N   . GLY D 1 132 ? -31.79030 24.84496  35.46403  1.000 69.83723  ? 112 GLY C N   1 
ATOM   4596 C  CA  . GLY D 1 132 ? -33.14328 25.17854  35.06004  1.000 68.03368  ? 112 GLY C CA  1 
ATOM   4597 C  C   . GLY D 1 132 ? -34.09705 24.00298  35.03091  1.000 70.45687  ? 112 GLY C C   1 
ATOM   4598 O  O   . GLY D 1 132 ? -35.31929 24.21072  35.06604  1.000 77.54957  ? 112 GLY C O   1 
ATOM   4599 N  N   . SER D 1 133 ? -33.58684 22.77546  34.96349  1.000 66.01889  ? 113 SER C N   1 
ATOM   4600 C  CA  . SER D 1 133 ? -34.45154 21.60399  34.98218  1.000 64.28129  ? 113 SER C CA  1 
ATOM   4601 C  C   . SER D 1 133 ? -35.14048 21.47416  36.33462  1.000 58.69642  ? 113 SER C C   1 
ATOM   4602 O  O   . SER D 1 133 ? -34.55478 21.76842  37.38102  1.000 57.31633  ? 113 SER C O   1 
ATOM   4603 C  CB  . SER D 1 133 ? -33.64586 20.34100  34.67658  1.000 63.72419  ? 113 SER C CB  1 
ATOM   4604 O  OG  . SER D 1 133 ? -34.44711 19.17732  34.79790  1.000 43.41651  ? 113 SER C OG  1 
ATOM   4605 N  N   . LEU D 1 134 ? -36.39678 21.02713  36.30894  1.000 50.79608  ? 114 LEU C N   1 
ATOM   4606 C  CA  . LEU D 1 134 ? -37.21802 20.94552  37.51030  1.000 46.46981  ? 114 LEU C CA  1 
ATOM   4607 C  C   . LEU D 1 134 ? -37.57531 19.50932  37.88367  1.000 40.82213  ? 114 LEU C C   1 
ATOM   4608 O  O   . LEU D 1 134 ? -38.52866 19.28946  38.64001  1.000 35.12385  ? 114 LEU C O   1 
ATOM   4609 C  CB  . LEU D 1 134 ? -38.48449 21.78459  37.33764  1.000 44.88543  ? 114 LEU C CB  1 
ATOM   4610 C  CG  . LEU D 1 134 ? -38.24589 23.26633  37.03828  1.000 45.41675  ? 114 LEU C CG  1 
ATOM   4611 C  CD1 . LEU D 1 134 ? -39.56394 24.02215  37.03115  1.000 45.67256  ? 114 LEU C CD1 1 
ATOM   4612 C  CD2 . LEU D 1 134 ? -37.27144 23.87720  38.04052  1.000 46.06810  ? 114 LEU C CD2 1 
ATOM   4613 N  N   . VAL D 1 135 ? -36.82771 18.52733  37.37125  1.000 31.51463  ? 115 VAL C N   1 
ATOM   4614 C  CA  . VAL D 1 135 ? -37.08022 17.13629  37.73640  1.000 30.16011  ? 115 VAL C CA  1 
ATOM   4615 C  C   . VAL D 1 135 ? -36.78631 16.91219  39.21428  1.000 32.55229  ? 115 VAL C C   1 
ATOM   4616 O  O   . VAL D 1 135 ? -37.51867 16.19097  39.90386  1.000 34.15113  ? 115 VAL C O   1 
ATOM   4617 C  CB  . VAL D 1 135 ? -36.26063 16.18817  36.84102  1.000 34.37749  ? 115 VAL C CB  1 
ATOM   4618 C  CG1 . VAL D 1 135 ? -36.52413 14.74001  37.21748  1.000 28.78650  ? 115 VAL C CG1 1 
ATOM   4619 C  CG2 . VAL D 1 135 ? -36.59607 16.42749  35.37503  1.000 37.15129  ? 115 VAL C CG2 1 
ATOM   4620 N  N   . GLY D 1 136 ? -35.71469 17.52435  39.72563  1.000 31.81958  ? 116 GLY C N   1 
ATOM   4621 C  CA  . GLY D 1 136 ? -35.45722 17.46253  41.15574  1.000 26.62799  ? 116 GLY C CA  1 
ATOM   4622 C  C   . GLY D 1 136 ? -36.58521 18.06985  41.96683  1.000 32.57392  ? 116 GLY C C   1 
ATOM   4623 O  O   . GLY D 1 136 ? -36.95616 17.55094  43.02383  1.000 34.58298  ? 116 GLY C O   1 
ATOM   4624 N  N   . LEU D 1 137 ? -37.15245 19.17532  41.47667  1.000 36.75098  ? 117 LEU C N   1 
ATOM   4625 C  CA  . LEU D 1 137 ? -38.31399 19.76575  42.13168  1.000 29.68634  ? 117 LEU C CA  1 
ATOM   4626 C  C   . LEU D 1 137 ? -39.51451 18.82898  42.07315  1.000 34.29230  ? 117 LEU C C   1 
ATOM   4627 O  O   . LEU D 1 137 ? -40.25563 18.70731  43.05404  1.000 35.52832  ? 117 LEU C O   1 
ATOM   4628 C  CB  . LEU D 1 137 ? -38.64815 21.11397  41.49494  1.000 38.15247  ? 117 LEU C CB  1 
ATOM   4629 C  CG  . LEU D 1 137 ? -39.88353 21.82837  42.04405  1.000 29.22277  ? 117 LEU C CG  1 
ATOM   4630 C  CD1 . LEU D 1 137 ? -39.67852 22.20129  43.50010  1.000 27.53903  ? 117 LEU C CD1 1 
ATOM   4631 C  CD2 . LEU D 1 137 ? -40.20039 23.05552  41.21263  1.000 34.77972  ? 117 LEU C CD2 1 
ATOM   4632 N  N   . ARG D 1 138 ? -39.72574 18.16142  40.93401  1.000 30.75643  ? 118 ARG C N   1 
ATOM   4633 C  CA  . ARG D 1 138 ? -40.78203 17.15581  40.85422  1.000 32.06377  ? 118 ARG C CA  1 
ATOM   4634 C  C   . ARG D 1 138 ? -40.60072 16.09091  41.92915  1.000 33.22799  ? 118 ARG C C   1 
ATOM   4635 O  O   . ARG D 1 138 ? -41.54382 15.75614  42.65688  1.000 36.05645  ? 118 ARG C O   1 
ATOM   4636 C  CB  . ARG D 1 138 ? -40.79950 16.50213  39.47003  1.000 29.58452  ? 118 ARG C CB  1 
ATOM   4637 C  CG  . ARG D 1 138 ? -41.26139 17.37788  38.31931  1.000 33.46920  ? 118 ARG C CG  1 
ATOM   4638 C  CD  . ARG D 1 138 ? -41.23442 16.58379  37.01662  1.000 35.11708  ? 118 ARG C CD  1 
ATOM   4639 N  NE  . ARG D 1 138 ? -41.60180 17.38027  35.85136  1.000 45.09087  ? 118 ARG C NE  1 
ATOM   4640 C  CZ  . ARG D 1 138 ? -42.81899 17.42130  35.32442  1.000 49.06585  ? 118 ARG C CZ  1 
ATOM   4641 N  NH1 . ARG D 1 138 ? -43.82156 16.72892  35.84238  1.000 39.16677  ? 118 ARG C NH1 1 
ATOM   4642 N  NH2 . ARG D 1 138 ? -43.03562 18.17233  34.24777  1.000 43.80208  ? 118 ARG C NH2 1 
ATOM   4643 N  N   . CYS D 1 139 ? -39.38602 15.54588  42.04028  1.000 31.51599  ? 119 CYS C N   1 
ATOM   4644 C  CA  . CYS D 1 139 ? -39.14212 14.46524  42.99053  1.000 30.75328  ? 119 CYS C CA  1 
ATOM   4645 C  C   . CYS D 1 139 ? -39.33159 14.93737  44.42449  1.000 31.71012  ? 119 CYS C C   1 
ATOM   4646 O  O   . CYS D 1 139 ? -39.93959 14.23631  45.24204  1.000 30.65351  ? 119 CYS C O   1 
ATOM   4647 C  CB  . CYS D 1 139 ? -37.73538 13.89959  42.79959  1.000 28.43609  ? 119 CYS C CB  1 
ATOM   4648 S  SG  . CYS D 1 139 ? -37.41868 13.22192  41.16111  1.000 30.67507  ? 119 CYS C SG  1 
ATOM   4649 N  N   . LEU D 1 140 ? -38.82229 16.12641  44.75001  1.000 35.39948  ? 120 LEU C N   1 
ATOM   4650 C  CA  . LEU D 1 140 ? -38.94494 16.61638  46.11727  1.000 42.72720  ? 120 LEU C CA  1 
ATOM   4651 C  C   . LEU D 1 140 ? -40.39264 16.94407  46.46363  1.000 39.50868  ? 120 LEU C C   1 
ATOM   4652 O  O   . LEU D 1 140 ? -40.84719 16.64594  47.57309  1.000 36.80558  ? 120 LEU C O   1 
ATOM   4653 C  CB  . LEU D 1 140 ? -38.03687 17.82733  46.32624  1.000 39.53090  ? 120 LEU C CB  1 
ATOM   4654 C  CG  . LEU D 1 140 ? -36.68971 17.47629  46.95943  1.000 39.74970  ? 120 LEU C CG  1 
ATOM   4655 C  CD1 . LEU D 1 140 ? -35.73594 18.65483  46.91852  1.000 45.94097  ? 120 LEU C CD1 1 
ATOM   4656 C  CD2 . LEU D 1 140 ? -36.90947 17.01988  48.38910  1.000 46.90523  ? 120 LEU C CD2 1 
ATOM   4657 N  N   . ARG D 1 141 ? -41.14247 17.53525  45.52864  1.000 36.75808  ? 121 ARG C N   1 
ATOM   4658 C  CA  . ARG D 1 141 ? -42.54945 17.81219  45.79501  1.000 36.25889  ? 121 ARG C CA  1 
ATOM   4659 C  C   . ARG D 1 141 ? -43.34048 16.52448  45.96127  1.000 44.86702  ? 121 ARG C C   1 
ATOM   4660 O  O   . ARG D 1 141 ? -44.22481 16.44022  46.82153  1.000 41.84861  ? 121 ARG C O   1 
ATOM   4661 C  CB  . ARG D 1 141 ? -43.14652 18.66336  44.67787  1.000 37.72894  ? 121 ARG C CB  1 
ATOM   4662 C  CG  . ARG D 1 141 ? -42.69095 20.10878  44.70750  1.000 44.71625  ? 121 ARG C CG  1 
ATOM   4663 C  CD  . ARG D 1 141 ? -43.84845 21.06054  44.46970  1.000 38.65358  ? 121 ARG C CD  1 
ATOM   4664 N  NE  . ARG D 1 141 ? -44.84487 20.99528  45.53284  1.000 50.29702  ? 121 ARG C NE  1 
ATOM   4665 C  CZ  . ARG D 1 141 ? -46.08334 20.54743  45.37756  1.000 50.55555  ? 121 ARG C CZ  1 
ATOM   4666 N  NH1 . ARG D 1 141 ? -46.52818 20.13721  44.20127  1.000 44.50917  ? 121 ARG C NH1 1 
ATOM   4667 N  NH2 . ARG D 1 141 ? -46.89831 20.51758  46.42795  1.000 48.46734  ? 121 ARG C NH2 1 
ATOM   4668 N  N   . ARG D 1 142 ? -43.03557 15.50705  45.14913  1.000 40.29050  ? 122 ARG C N   1 
ATOM   4669 C  CA  . ARG D 1 142 ? -43.70738 14.22216  45.30153  1.000 37.96147  ? 122 ARG C CA  1 
ATOM   4670 C  C   . ARG D 1 142 ? -43.37968 13.58822  46.64454  1.000 35.88000  ? 122 ARG C C   1 
ATOM   4671 O  O   . ARG D 1 142 ? -44.26125 13.02304  47.29889  1.000 37.66714  ? 122 ARG C O   1 
ATOM   4672 C  CB  . ARG D 1 142 ? -43.31878 13.28224  44.16417  1.000 34.20872  ? 122 ARG C CB  1 
ATOM   4673 C  CG  . ARG D 1 142 ? -44.04096 11.94870  44.19204  1.000 30.49915  ? 122 ARG C CG  1 
ATOM   4674 C  CD  . ARG D 1 142 ? -45.48519 12.07811  43.72966  1.000 30.75156  ? 122 ARG C CD  1 
ATOM   4675 N  NE  . ARG D 1 142 ? -46.14194 10.77703  43.65638  1.000 44.67503  ? 122 ARG C NE  1 
ATOM   4676 C  CZ  . ARG D 1 142 ? -47.31960 10.55598  43.08753  1.000 36.08026  ? 122 ARG C CZ  1 
ATOM   4677 N  NH1 . ARG D 1 142 ? -47.99819 11.52783  42.50116  1.000 28.58137  ? 122 ARG C NH1 1 
ATOM   4678 N  NH2 . ARG D 1 142 ? -47.82863 9.32741   43.10697  1.000 38.83399  ? 122 ARG C NH2 1 
ATOM   4679 N  N   . ALA D 1 143 ? -42.11827 13.67125  47.07260  1.000 33.89246  ? 123 ALA C N   1 
ATOM   4680 C  CA  . ALA D 1 143 ? -41.75253 13.13418  48.37800  1.000 37.67093  ? 123 ALA C CA  1 
ATOM   4681 C  C   . ALA D 1 143 ? -42.48191 13.86992  49.49434  1.000 42.75271  ? 123 ALA C C   1 
ATOM   4682 O  O   . ALA D 1 143 ? -43.00640 13.24108  50.42120  1.000 39.81206  ? 123 ALA C O   1 
ATOM   4683 C  CB  . ALA D 1 143 ? -40.23791 13.20894  48.57433  1.000 31.58209  ? 123 ALA C CB  1 
ATOM   4684 N  N   . ILE D 1 144 ? -42.54824 15.20169  49.40595  1.000 45.28957  ? 124 ILE C N   1 
ATOM   4685 C  CA  . ILE D 1 144 ? -43.22457 15.99491  50.43053  1.000 46.07667  ? 124 ILE C CA  1 
ATOM   4686 C  C   . ILE D 1 144 ? -44.70810 15.64612  50.48484  1.000 51.03055  ? 124 ILE C C   1 
ATOM   4687 O  O   . ILE D 1 144 ? -45.27558 15.45392  51.56455  1.000 53.04251  ? 124 ILE C O   1 
ATOM   4688 C  CB  . ILE D 1 144 ? -43.00363 17.49859  50.17866  1.000 44.33219  ? 124 ILE C CB  1 
ATOM   4689 C  CG1 . ILE D 1 144 ? -41.53295 17.87087  50.37603  1.000 43.00577  ? 124 ILE C CG1 1 
ATOM   4690 C  CG2 . ILE D 1 144 ? -43.87857 18.33290  51.10168  1.000 35.42030  ? 124 ILE C CG2 1 
ATOM   4691 C  CD1 . ILE D 1 144 ? -41.16898 19.22842  49.80687  1.000 43.24512  ? 124 ILE C CD1 1 
ATOM   4692 N  N   . GLU D 1 145 ? -45.35875 15.55067  49.32194  1.000 51.03264  ? 125 GLU C N   1 
ATOM   4693 C  CA  . GLU D 1 145 ? -46.78774 15.24546  49.30614  1.000 47.63401  ? 125 GLU C CA  1 
ATOM   4694 C  C   . GLU D 1 145 ? -47.06347 13.82696  49.79233  1.000 52.79414  ? 125 GLU C C   1 
ATOM   4695 O  O   . GLU D 1 145 ? -48.02078 13.59856  50.54156  1.000 56.84879  ? 125 GLU C O   1 
ATOM   4696 C  CB  . GLU D 1 145 ? -47.35982 15.44613  47.90336  1.000 49.29984  ? 125 GLU C CB  1 
ATOM   4697 C  CG  . GLU D 1 145 ? -47.58023 16.89393  47.51717  1.000 69.37040  ? 125 GLU C CG  1 
ATOM   4698 C  CD  . GLU D 1 145 ? -48.11165 17.04042  46.10626  1.000 78.92838  ? 125 GLU C CD  1 
ATOM   4699 O  OE1 . GLU D 1 145 ? -48.96528 17.92380  45.87636  1.000 90.00222  ? 125 GLU C OE1 1 
ATOM   4700 O  OE2 . GLU D 1 145 ? -47.67957 16.26445  45.22850  1.000 79.33322  ? 125 GLU C OE2 1 
ATOM   4701 N  N   . THR D 1 146 ? -46.24293 12.85971  49.37284  1.000 48.61977  ? 126 THR C N   1 
ATOM   4702 C  CA  . THR D 1 146 ? -46.43970 11.48029  49.80179  1.000 44.60963  ? 126 THR C CA  1 
ATOM   4703 C  C   . THR D 1 146 ? -46.21092 11.33573  51.29926  1.000 48.99551  ? 126 THR C C   1 
ATOM   4704 O  O   . THR D 1 146 ? -46.89831 10.55507  51.96722  1.000 50.39312  ? 126 THR C O   1 
ATOM   4705 C  CB  . THR D 1 146 ? -45.50498 10.55359  49.02397  1.000 40.52226  ? 126 THR C CB  1 
ATOM   4706 O  OG1 . THR D 1 146 ? -45.66296 10.78753  47.61892  1.000 42.61395  ? 126 THR C OG1 1 
ATOM   4707 C  CG2 . THR D 1 146 ? -45.81573 9.09579   49.32587  1.000 35.34488  ? 126 THR C CG2 1 
ATOM   4708 N  N   . ALA D 1 147 ? -45.25298 12.08645  51.84792  1.000 51.98549  ? 127 ALA C N   1 
ATOM   4709 C  CA  . ALA D 1 147 ? -45.01077 12.03073  53.28293  1.000 51.28395  ? 127 ALA C CA  1 
ATOM   4710 C  C   . ALA D 1 147 ? -46.10136 12.76314  54.05544  1.000 55.18002  ? 127 ALA C C   1 
ATOM   4711 O  O   . ALA D 1 147 ? -46.44511 12.36488  55.17203  1.000 56.76314  ? 127 ALA C O   1 
ATOM   4712 C  CB  . ALA D 1 147 ? -43.63150 12.60623  53.60461  1.000 42.85500  ? 127 ALA C CB  1 
ATOM   4713 N  N   . ALA D 1 148 ? -46.65753 13.83563  53.48445  1.000 63.00888  ? 128 ALA C N   1 
ATOM   4714 C  CA  . ALA D 1 148 ? -47.78627 14.50681  54.12286  1.000 61.02306  ? 128 ALA C CA  1 
ATOM   4715 C  C   . ALA D 1 148 ? -48.99046 13.57884  54.18595  1.000 59.21497  ? 128 ALA C C   1 
ATOM   4716 O  O   . ALA D 1 148 ? -49.64625 13.45681  55.22902  1.000 62.30763  ? 128 ALA C O   1 
ATOM   4717 C  CB  . ALA D 1 148 ? -48.12689 15.79884  53.37654  1.000 50.48203  ? 128 ALA C CB  1 
ATOM   4718 N  N   . GLN D 1 149 ? -49.29429 12.91796  53.07039  1.000 51.11998  ? 129 GLN C N   1 
ATOM   4719 C  CA  . GLN D 1 149 ? -50.21767 11.79888  53.08228  1.000 56.12930  ? 129 GLN C CA  1 
ATOM   4720 C  C   . GLN D 1 149 ? -49.63795 10.67821  53.94649  1.000 65.17166  ? 129 GLN C C   1 
ATOM   4721 O  O   . GLN D 1 149 ? -48.46236 10.69181  54.32102  1.000 69.16482  ? 129 GLN C O   1 
ATOM   4722 C  CB  . GLN D 1 149 ? -50.47072 11.30008  51.66118  1.000 51.87902  ? 129 GLN C CB  1 
ATOM   4723 C  CG  . GLN D 1 149 ? -50.93650 12.37609  50.68546  1.000 64.78841  ? 129 GLN C CG  1 
ATOM   4724 C  CD  . GLN D 1 149 ? -50.89035 11.89185  49.25163  1.000 79.25602  ? 129 GLN C CD  1 
ATOM   4725 O  OE1 . GLN D 1 149 ? -50.86036 12.68275  48.30550  1.000 69.23589  ? 129 GLN C OE1 1 
ATOM   4726 N  NE2 . GLN D 1 149 ? -50.87216 10.57604  49.08477  1.000 75.26589  ? 129 GLN C NE2 1 
ATOM   4727 N  N   . ALA D 1 150 ? -50.47595 9.69867   54.26966  1.000 63.96800  ? 130 ALA C N   1 
ATOM   4728 C  CA  . ALA D 1 150 ? -50.10469 8.57874   55.13108  1.000 76.15871  ? 130 ALA C CA  1 
ATOM   4729 C  C   . ALA D 1 150 ? -49.74696 9.01724   56.54806  1.000 71.02094  ? 130 ALA C C   1 
ATOM   4730 O  O   . ALA D 1 150 ? -49.14407 8.23940   57.29786  1.000 74.02223  ? 130 ALA C O   1 
ATOM   4731 C  CB  . ALA D 1 150 ? -48.95486 7.75356   54.53123  1.000 64.17905  ? 130 ALA C CB  1 
ATOM   4732 N  N   . GLY D 1 151 ? -50.07873 10.25275  56.92236  1.000 66.92909  ? 131 GLY C N   1 
ATOM   4733 C  CA  . GLY D 1 151 ? -49.94467 10.70542  58.29320  1.000 77.25998  ? 131 GLY C CA  1 
ATOM   4734 C  C   . GLY D 1 151 ? -48.55971 11.12012  58.73358  1.000 76.07067  ? 131 GLY C C   1 
ATOM   4735 O  O   . GLY D 1 151 ? -48.26529 11.06045  59.93098  1.000 81.08049  ? 131 GLY C O   1 
ATOM   4736 N  N   . GLY D 1 152 ? -47.70193 11.55544  57.81480  1.000 71.36022  ? 132 GLY C N   1 
ATOM   4737 C  CA  . GLY D 1 152 ? -46.35265 11.94227  58.19662  1.000 61.30583  ? 132 GLY C CA  1 
ATOM   4738 C  C   . GLY D 1 152 ? -46.33680 13.25322  58.96349  1.000 64.53054  ? 132 GLY C C   1 
ATOM   4739 O  O   . GLY D 1 152 ? -47.03086 14.21204  58.61977  1.000 63.45838  ? 132 GLY C O   1 
ATOM   4740 N  N   . ASP D 1 153 ? -45.52142 13.28722  60.01690  1.000 73.15187  ? 133 ASP C N   1 
ATOM   4741 C  CA  . ASP D 1 153 ? -45.39307 14.46515  60.86409  1.000 67.23669  ? 133 ASP C CA  1 
ATOM   4742 C  C   . ASP D 1 153 ? -44.27863 15.39322  60.40127  1.000 68.03087  ? 133 ASP C C   1 
ATOM   4743 O  O   . ASP D 1 153 ? -44.41600 16.61735  60.50779  1.000 67.63660  ? 133 ASP C O   1 
ATOM   4744 C  CB  . ASP D 1 153 ? -45.15082 14.03019  62.31470  1.000 70.75815  ? 133 ASP C CB  1 
ATOM   4745 C  CG  . ASP D 1 153 ? -45.44470 15.12877  63.32019  1.000 75.68067  ? 133 ASP C CG  1 
ATOM   4746 O  OD1 . ASP D 1 153 ? -44.77956 16.18443  63.27183  1.000 84.04146  ? 133 ASP C OD1 1 
ATOM   4747 O  OD2 . ASP D 1 153 ? -46.34779 14.93530  64.16483  1.000 79.47428  ? 133 ASP C OD2 1 
ATOM   4748 N  N   . ALA D 1 154 ? -43.18897 14.84012  59.87511  1.000 69.43047  ? 134 ALA C N   1 
ATOM   4749 C  CA  . ALA D 1 154 ? -42.07264 15.63950  59.39217  1.000 67.39042  ? 134 ALA C CA  1 
ATOM   4750 C  C   . ALA D 1 154 ? -41.29838 14.82510  58.36780  1.000 50.48198  ? 134 ALA C C   1 
ATOM   4751 O  O   . ALA D 1 154 ? -41.42279 13.59923  58.29884  1.000 51.75605  ? 134 ALA C O   1 
ATOM   4752 C  CB  . ALA D 1 154 ? -41.15498 16.08168  60.53629  1.000 58.42657  ? 134 ALA C CB  1 
ATOM   4753 N  N   . LEU D 1 155 ? -40.50087 15.52566  57.56449  1.000 50.24137  ? 135 LEU C N   1 
ATOM   4754 C  CA  . LEU D 1 155 ? -39.65332 14.90232  56.55373  1.000 46.40290  ? 135 LEU C CA  1 
ATOM   4755 C  C   . LEU D 1 155 ? -38.20433 15.20963  56.90466  1.000 42.34504  ? 135 LEU C C   1 
ATOM   4756 O  O   . LEU D 1 155 ? -37.77901 16.36862  56.84851  1.000 46.66840  ? 135 LEU C O   1 
ATOM   4757 C  CB  . LEU D 1 155 ? -40.00566 15.40190  55.15181  1.000 40.02784  ? 135 LEU C CB  1 
ATOM   4758 C  CG  . LEU D 1 155 ? -39.31714 14.66765  53.99986  1.000 44.26717  ? 135 LEU C CG  1 
ATOM   4759 C  CD1 . LEU D 1 155 ? -39.54906 13.16962  54.11629  1.000 34.59219  ? 135 LEU C CD1 1 
ATOM   4760 C  CD2 . LEU D 1 155 ? -39.80902 15.18253  52.65619  1.000 36.83679  ? 135 LEU C CD2 1 
ATOM   4761 N  N   . ARG D 1 156 ? -37.45977 14.17826  57.28631  1.000 45.71771  ? 136 ARG C N   1 
ATOM   4762 C  CA  . ARG D 1 156 ? -36.05322 14.29740  57.63144  1.000 47.57846  ? 136 ARG C CA  1 
ATOM   4763 C  C   . ARG D 1 156 ? -35.20359 13.69534  56.52135  1.000 56.57327  ? 136 ARG C C   1 
ATOM   4764 O  O   . ARG D 1 156 ? -35.61737 12.74777  55.84578  1.000 50.48614  ? 136 ARG C O   1 
ATOM   4765 C  CB  . ARG D 1 156 ? -35.75655 13.60101  58.96250  1.000 56.81857  ? 136 ARG C CB  1 
ATOM   4766 C  CG  . ARG D 1 156 ? -36.53737 14.17012  60.13406  1.000 56.56018  ? 136 ARG C CG  1 
ATOM   4767 C  CD  . ARG D 1 156 ? -36.43412 13.28232  61.36118  1.000 62.32819  ? 136 ARG C CD  1 
ATOM   4768 N  NE  . ARG D 1 156 ? -37.07392 13.89579  62.51868  1.000 75.55531  ? 136 ARG C NE  1 
ATOM   4769 C  CZ  . ARG D 1 156 ? -37.19304 13.31788  63.70591  1.000 69.99793  ? 136 ARG C CZ  1 
ATOM   4770 N  NH1 . ARG D 1 156 ? -36.73746 12.09586  63.92919  1.000 62.69385  ? 136 ARG C NH1 1 
ATOM   4771 N  NH2 . ARG D 1 156 ? -37.78333 13.98357  64.69432  1.000 75.91125  ? 136 ARG C NH2 1 
ATOM   4772 N  N   . SER D 1 157 ? -34.01003 14.25320  56.33495  1.000 56.18800  ? 137 SER C N   1 
ATOM   4773 C  CA  . SER D 1 157 ? -33.16209 13.79393  55.24360  1.000 44.31496  ? 137 SER C CA  1 
ATOM   4774 C  C   . SER D 1 157 ? -31.70582 14.09253  55.56733  1.000 51.80102  ? 137 SER C C   1 
ATOM   4775 O  O   . SER D 1 157 ? -31.39537 14.97427  56.37090  1.000 51.59457  ? 137 SER C O   1 
ATOM   4776 C  CB  . SER D 1 157 ? -33.56755 14.44392  53.91470  1.000 50.54740  ? 137 SER C CB  1 
ATOM   4777 O  OG  . SER D 1 157 ? -32.87947 13.85797  52.82209  1.000 42.75431  ? 137 SER C OG  1 
ATOM   4778 N  N   . GLU D 1 158 ? -30.81640 13.33599  54.93014  1.000 47.19194  ? 138 GLU C N   1 
ATOM   4779 C  CA  . GLU D 1 158 ? -29.38311 13.58902  54.96759  1.000 41.60944  ? 138 GLU C CA  1 
ATOM   4780 C  C   . GLU D 1 158 ? -28.95183 14.13869  53.61671  1.000 43.17748  ? 138 GLU C C   1 
ATOM   4781 O  O   . GLU D 1 158 ? -29.29299 13.56821  52.57608  1.000 46.18650  ? 138 GLU C O   1 
ATOM   4782 C  CB  . GLU D 1 158 ? -28.60160 12.31667  55.29511  1.000 46.43927  ? 138 GLU C CB  1 
ATOM   4783 C  CG  . GLU D 1 158 ? -27.09172 12.49838  55.20302  1.000 51.93339  ? 138 GLU C CG  1 
ATOM   4784 C  CD  . GLU D 1 158 ? -26.32854 11.21931  55.46686  1.000 58.96743  ? 138 GLU C CD  1 
ATOM   4785 O  OE1 . GLU D 1 158 ? -26.48252 10.64536  56.56456  1.000 71.53297  ? 138 GLU C OE1 1 
ATOM   4786 O  OE2 . GLU D 1 158 ? -25.57432 10.78596  54.57190  1.000 55.07065  ? 138 GLU C OE2 1 
ATOM   4787 N  N   . ALA D 1 159 ? -28.21020 15.24247  53.63209  1.000 41.49540  ? 139 ALA C N   1 
ATOM   4788 C  CA  . ALA D 1 159 ? -27.82936 15.92380  52.40524  1.000 34.96598  ? 139 ALA C CA  1 
ATOM   4789 C  C   . ALA D 1 159 ? -26.32959 16.18466  52.38722  1.000 40.93154  ? 139 ALA C C   1 
ATOM   4790 O  O   . ALA D 1 159 ? -25.66599 16.20434  53.42549  1.000 41.51523  ? 139 ALA C O   1 
ATOM   4791 C  CB  . ALA D 1 159 ? -28.59304 17.24530  52.23829  1.000 36.99806  ? 139 ALA C CB  1 
ATOM   4792 N  N   . ASN D 1 160 ? -25.80246 16.38073  51.17766  1.000 51.09467  ? 140 ASN C N   1 
ATOM   4793 C  CA  . ASN D 1 160 ? -24.41552 16.77200  50.98088  1.000 46.49612  ? 140 ASN C CA  1 
ATOM   4794 C  C   . ASN D 1 160 ? -24.37257 18.27179  50.73825  1.000 39.49106  ? 140 ASN C C   1 
ATOM   4795 O  O   . ASN D 1 160 ? -24.86331 18.73196  49.69708  1.000 47.18665  ? 140 ASN C O   1 
ATOM   4796 C  CB  . ASN D 1 160 ? -23.80869 16.01974  49.79602  1.000 42.64434  ? 140 ASN C CB  1 
ATOM   4797 C  CG  . ASN D 1 160 ? -22.31927 16.30250  49.60630  1.000 56.03328  ? 140 ASN C CG  1 
ATOM   4798 O  OD1 . ASN D 1 160 ? -21.78792 17.30210  50.09186  1.000 54.88541  ? 140 ASN C OD1 1 
ATOM   4799 N  ND2 . ASN D 1 160 ? -21.64248 15.41547  48.88660  1.000 54.64384  ? 140 ASN C ND2 1 
ATOM   4800 N  N   . PRO D 1 161 ? -23.81569 19.07185  51.65103  1.000 45.67178  ? 141 PRO C N   1 
ATOM   4801 C  CA  . PRO D 1 161 ? -23.76463 20.52294  51.41244  1.000 41.48091  ? 141 PRO C CA  1 
ATOM   4802 C  C   . PRO D 1 161 ? -22.88673 20.91550  50.23409  1.000 45.14773  ? 141 PRO C C   1 
ATOM   4803 O  O   . PRO D 1 161 ? -23.07143 22.01222  49.69021  1.000 43.96375  ? 141 PRO C O   1 
ATOM   4804 C  CB  . PRO D 1 161 ? -23.21416 21.07843  52.73334  1.000 36.84531  ? 141 PRO C CB  1 
ATOM   4805 C  CG  . PRO D 1 161 ? -22.47374 19.93516  53.34442  1.000 45.90407  ? 141 PRO C CG  1 
ATOM   4806 C  CD  . PRO D 1 161 ? -23.22965 18.70063  52.95007  1.000 47.42901  ? 141 PRO C CD  1 
ATOM   4807 N  N   . ASP D 1 162 ? -21.94912 20.05976  49.81541  1.000 45.48306  ? 142 ASP C N   1 
ATOM   4808 C  CA  . ASP D 1 162 ? -21.10552 20.35602  48.66332  1.000 44.10645  ? 142 ASP C CA  1 
ATOM   4809 C  C   . ASP D 1 162 ? -21.81862 20.15049  47.33350  1.000 43.35012  ? 142 ASP C C   1 
ATOM   4810 O  O   . ASP D 1 162 ? -21.28108 20.55072  46.29538  1.000 46.87032  ? 142 ASP C O   1 
ATOM   4811 C  CB  . ASP D 1 162 ? -19.83080 19.50843  48.70855  1.000 48.18610  ? 142 ASP C CB  1 
ATOM   4812 C  CG  . ASP D 1 162 ? -18.83030 20.02249  49.72423  1.000 56.36769  ? 142 ASP C CG  1 
ATOM   4813 O  OD1 . ASP D 1 162 ? -19.00544 21.16357  50.19786  1.000 58.45450  ? 142 ASP C OD1 1 
ATOM   4814 O  OD2 . ASP D 1 162 ? -17.87000 19.29212  50.05064  1.000 70.63642  ? 142 ASP C OD2 1 
ATOM   4815 N  N   . LEU D 1 163 ? -23.00382 19.54254  47.33584  1.000 41.94626  ? 143 LEU C N   1 
ATOM   4816 C  CA  . LEU D 1 163 ? -23.85312 19.48366  46.14662  1.000 43.94879  ? 143 LEU C CA  1 
ATOM   4817 C  C   . LEU D 1 163 ? -24.70600 20.74615  46.15268  1.000 42.31891  ? 143 LEU C C   1 
ATOM   4818 O  O   . LEU D 1 163 ? -25.80674 20.77577  46.70446  1.000 39.79472  ? 143 LEU C O   1 
ATOM   4819 C  CB  . LEU D 1 163 ? -24.69917 18.21628  46.14407  1.000 46.25045  ? 143 LEU C CB  1 
ATOM   4820 C  CG  . LEU D 1 163 ? -23.92975 16.89292  46.20774  1.000 44.34884  ? 143 LEU C CG  1 
ATOM   4821 C  CD1 . LEU D 1 163 ? -24.87732 15.70817  46.08402  1.000 37.66464  ? 143 LEU C CD1 1 
ATOM   4822 C  CD2 . LEU D 1 163 ? -22.84734 16.83542  45.13652  1.000 45.59735  ? 143 LEU C CD2 1 
ATOM   4823 N  N   . SER D 1 164 ? -24.18502 21.80540  45.52396  1.000 43.80036  ? 144 SER C N   1 
ATOM   4824 C  CA  . SER D 1 164 ? -24.75729 23.13922  45.70064  1.000 42.85163  ? 144 SER C CA  1 
ATOM   4825 C  C   . SER D 1 164 ? -26.18235 23.22866  45.16498  1.000 42.90750  ? 144 SER C C   1 
ATOM   4826 O  O   . SER D 1 164 ? -27.05471 23.81759  45.81232  1.000 52.00916  ? 144 SER C O   1 
ATOM   4827 C  CB  . SER D 1 164 ? -23.86737 24.18553  45.02889  1.000 42.62692  ? 144 SER C CB  1 
ATOM   4828 O  OG  . SER D 1 164 ? -22.59179 24.23760  45.64391  1.000 56.31879  ? 144 SER C OG  1 
ATOM   4829 N  N   . ALA D 1 165 ? -26.43951 22.66095  43.98432  1.000 47.51554  ? 145 ALA C N   1 
ATOM   4830 C  CA  . ALA D 1 165 ? -27.77694 22.74363  43.40115  1.000 38.63256  ? 145 ALA C CA  1 
ATOM   4831 C  C   . ALA D 1 165 ? -28.80187 22.02128  44.26708  1.000 45.98625  ? 145 ALA C C   1 
ATOM   4832 O  O   . ALA D 1 165 ? -29.87225 22.56443  44.57188  1.000 44.00177  ? 145 ALA C O   1 
ATOM   4833 C  CB  . ALA D 1 165 ? -27.76923 22.16815  41.98558  1.000 28.86539  ? 145 ALA C CB  1 
ATOM   4834 N  N   . THR D 1 166 ? -28.48788 20.78774  44.67085  1.000 40.39811  ? 146 THR C N   1 
ATOM   4835 C  CA  . THR D 1 166 ? -29.40251 20.02016  45.51028  1.000 35.38867  ? 146 THR C CA  1 
ATOM   4836 C  C   . THR D 1 166 ? -29.60711 20.69303  46.86011  1.000 39.32622  ? 146 THR C C   1 
ATOM   4837 O  O   . THR D 1 166 ? -30.73158 20.74434  47.37621  1.000 37.31358  ? 146 THR C O   1 
ATOM   4838 C  CB  . THR D 1 166 ? -28.86708 18.60252  45.70555  1.000 28.17578  ? 146 THR C CB  1 
ATOM   4839 O  OG1 . THR D 1 166 ? -28.48890 18.05460  44.43569  1.000 39.01667  ? 146 THR C OG1 1 
ATOM   4840 C  CG2 . THR D 1 166 ? -29.92764 17.71505  46.34487  1.000 26.09164  ? 146 THR C CG2 1 
ATOM   4841 N  N   . ARG D 1 167 ? -28.52614 21.21016  47.44839  1.000 32.54270  ? 147 ARG C N   1 
ATOM   4842 C  CA  . ARG D 1 167 ? -28.63106 21.88413  48.73626  1.000 40.10869  ? 147 ARG C CA  1 
ATOM   4843 C  C   . ARG D 1 167 ? -29.51009 23.12328  48.63565  1.000 43.26299  ? 147 ARG C C   1 
ATOM   4844 O  O   . ARG D 1 167 ? -30.35960 23.36410  49.50135  1.000 35.07865  ? 147 ARG C O   1 
ATOM   4845 C  CB  . ARG D 1 167 ? -27.23760 22.24938  49.24546  1.000 34.05677  ? 147 ARG C CB  1 
ATOM   4846 C  CG  . ARG D 1 167 ? -27.22183 22.79230  50.65849  1.000 44.09239  ? 147 ARG C CG  1 
ATOM   4847 C  CD  . ARG D 1 167 ? -27.69067 21.74420  51.65508  1.000 40.51565  ? 147 ARG C CD  1 
ATOM   4848 N  NE  . ARG D 1 167 ? -27.84203 22.30427  52.99236  1.000 57.50935  ? 147 ARG C NE  1 
ATOM   4849 C  CZ  . ARG D 1 167 ? -28.95695 22.85886  53.44821  1.000 55.29944  ? 147 ARG C CZ  1 
ATOM   4850 N  NH1 . ARG D 1 167 ? -30.04622 22.93633  52.70109  1.000 48.90773  ? 147 ARG C NH1 1 
ATOM   4851 N  NH2 . ARG D 1 167 ? -28.97904 23.35083  54.68339  1.000 49.77914  ? 147 ARG C NH2 1 
ATOM   4852 N  N   . SER D 1 168 ? -29.32650 23.91596  47.57752  1.000 47.42859  ? 148 SER C N   1 
ATOM   4853 C  CA  . SER D 1 168 ? -30.13967 25.11208  47.39331  1.000 39.83703  ? 148 SER C CA  1 
ATOM   4854 C  C   . SER D 1 168 ? -31.60477 24.75339  47.18659  1.000 42.04568  ? 148 SER C C   1 
ATOM   4855 O  O   . SER D 1 168 ? -32.49512 25.40798  47.74279  1.000 40.50160  ? 148 SER C O   1 
ATOM   4856 C  CB  . SER D 1 168 ? -29.60939 25.92457  46.21238  1.000 30.33852  ? 148 SER C CB  1 
ATOM   4857 O  OG  . SER D 1 168 ? -30.39332 27.08372  45.99776  1.000 47.16853  ? 148 SER C OG  1 
ATOM   4858 N  N   . LEU D 1 169 ? -31.87428 23.70987  46.39537  1.000 41.89279  ? 149 LEU C N   1 
ATOM   4859 C  CA  . LEU D 1 169 ? -33.25241 23.27172  46.19559  1.000 36.99330  ? 149 LEU C CA  1 
ATOM   4860 C  C   . LEU D 1 169 ? -33.88906 22.83229  47.50950  1.000 38.27278  ? 149 LEU C C   1 
ATOM   4861 O  O   . LEU D 1 169 ? -35.04694 23.16587  47.78853  1.000 40.75959  ? 149 LEU C O   1 
ATOM   4862 C  CB  . LEU D 1 169 ? -33.29984 22.13997  45.16800  1.000 32.25621  ? 149 LEU C CB  1 
ATOM   4863 C  CG  . LEU D 1 169 ? -34.68631 21.57048  44.85550  1.000 26.45206  ? 149 LEU C CG  1 
ATOM   4864 C  CD1 . LEU D 1 169 ? -35.60395 22.66636  44.34278  1.000 28.33944  ? 149 LEU C CD1 1 
ATOM   4865 C  CD2 . LEU D 1 169 ? -34.60054 20.42579  43.85226  1.000 30.84180  ? 149 LEU C CD2 1 
ATOM   4866 N  N   . LEU D 1 170 ? -33.14681 22.08577  48.33230  1.000 41.48397  ? 150 LEU C N   1 
ATOM   4867 C  CA  . LEU D 1 170 ? -33.67549 21.67131  49.62902  1.000 40.40443  ? 150 LEU C CA  1 
ATOM   4868 C  C   . LEU D 1 170 ? -33.92591 22.87170  50.53355  1.000 43.93005  ? 150 LEU C C   1 
ATOM   4869 O  O   . LEU D 1 170 ? -34.90325 22.89495  51.29080  1.000 46.38303  ? 150 LEU C O   1 
ATOM   4870 C  CB  . LEU D 1 170 ? -32.71747 20.68518  50.29778  1.000 37.08052  ? 150 LEU C CB  1 
ATOM   4871 C  CG  . LEU D 1 170 ? -32.69459 19.27055  49.71565  1.000 40.12016  ? 150 LEU C CG  1 
ATOM   4872 C  CD1 . LEU D 1 170 ? -31.41427 18.54104  50.09670  1.000 19.98644  ? 150 LEU C CD1 1 
ATOM   4873 C  CD2 . LEU D 1 170 ? -33.91493 18.49212  50.18383  1.000 32.97771  ? 150 LEU C CD2 1 
ATOM   4874 N  N   . ASP D 1 171 ? -33.05672 23.88173  50.46506  1.000 41.61419  ? 151 ASP C N   1 
ATOM   4875 C  CA  . ASP D 1 171 ? -33.23323 25.06217  51.30512  1.000 43.90032  ? 151 ASP C CA  1 
ATOM   4876 C  C   . ASP D 1 171 ? -34.46259 25.86277  50.89041  1.000 47.16077  ? 151 ASP C C   1 
ATOM   4877 O  O   . ASP D 1 171 ? -35.21660 26.33959  51.74720  1.000 50.68221  ? 151 ASP C O   1 
ATOM   4878 C  CB  . ASP D 1 171 ? -31.98149 25.93562  51.25160  1.000 44.64602  ? 151 ASP C CB  1 
ATOM   4879 C  CG  . ASP D 1 171 ? -32.11597 27.19622  52.08367  1.000 55.83420  ? 151 ASP C CG  1 
ATOM   4880 O  OD1 . ASP D 1 171 ? -32.16810 27.08705  53.32868  1.000 55.83500  ? 151 ASP C OD1 1 
ATOM   4881 O  OD2 . ASP D 1 171 ? -32.17106 28.29482  51.49148  1.000 56.76652  ? 151 ASP C OD2 1 
ATOM   4882 N  N   . ILE D 1 172 ? -34.68503 26.01445  49.58176  1.000 44.09503  ? 152 ILE C N   1 
ATOM   4883 C  CA  . ILE D 1 172 ? -35.83386 26.77928  49.10021  1.000 41.41410  ? 152 ILE C CA  1 
ATOM   4884 C  C   . ILE D 1 172 ? -37.14211 26.12478  49.52695  1.000 42.62221  ? 152 ILE C C   1 
ATOM   4885 O  O   . ILE D 1 172 ? -38.12283 26.81506  49.83089  1.000 43.37164  ? 152 ILE C O   1 
ATOM   4886 C  CB  . ILE D 1 172 ? -35.75400 26.94315  47.56780  1.000 40.62820  ? 152 ILE C CB  1 
ATOM   4887 C  CG1 . ILE D 1 172 ? -34.51286 27.74811  47.17876  1.000 46.48823  ? 152 ILE C CG1 1 
ATOM   4888 C  CG2 . ILE D 1 172 ? -37.00473 27.62073  47.02438  1.000 40.86364  ? 152 ILE C CG2 1 
ATOM   4889 C  CD1 . ILE D 1 172 ? -34.24073 27.76316  45.68860  1.000 39.62916  ? 152 ILE C CD1 1 
ATOM   4890 N  N   . LEU D 1 173 ? -37.17844 24.79445  49.57723  1.000 53.31855  ? 153 LEU C N   1 
ATOM   4891 C  CA  . LEU D 1 173 ? -38.39835 24.07103  49.91671  1.000 44.72978  ? 153 LEU C CA  1 
ATOM   4892 C  C   . LEU D 1 173 ? -38.63756 23.95561  51.41856  1.000 46.69849  ? 153 LEU C C   1 
ATOM   4893 O  O   . LEU D 1 173 ? -39.61344 23.31508  51.82106  1.000 52.07829  ? 153 LEU C O   1 
ATOM   4894 C  CB  . LEU D 1 173 ? -38.37875 22.67743  49.28101  1.000 44.15462  ? 153 LEU C CB  1 
ATOM   4895 C  CG  . LEU D 1 173 ? -38.95343 22.53287  47.86609  1.000 48.80433  ? 153 LEU C CG  1 
ATOM   4896 C  CD1 . LEU D 1 173 ? -40.45167 22.78167  47.87610  1.000 49.64186  ? 153 LEU C CD1 1 
ATOM   4897 C  CD2 . LEU D 1 173 ? -38.26636 23.45825  46.86393  1.000 43.14133  ? 153 LEU C CD2 1 
ATOM   4898 N  N   . GLY D 1 174 ? -37.78572 24.54285  52.25357  1.000 46.54740  ? 154 GLY C N   1 
ATOM   4899 C  CA  . GLY D 1 174 ? -38.03626 24.60124  53.67966  1.000 45.13389  ? 154 GLY C CA  1 
ATOM   4900 C  C   . GLY D 1 174 ? -37.26415 23.63018  54.54648  1.000 50.01149  ? 154 GLY C C   1 
ATOM   4901 O  O   . GLY D 1 174 ? -37.58642 23.50198  55.73332  1.000 56.43231  ? 154 GLY C O   1 
ATOM   4902 N  N   . PHE D 1 175 ? -36.25927 22.94830  54.00647  1.000 45.89790  ? 155 PHE C N   1 
ATOM   4903 C  CA  . PHE D 1 175 ? -35.46760 22.01934  54.80327  1.000 52.90287  ? 155 PHE C CA  1 
ATOM   4904 C  C   . PHE D 1 175 ? -34.43747 22.79485  55.61555  1.000 59.56816  ? 155 PHE C C   1 
ATOM   4905 O  O   . PHE D 1 175 ? -33.57505 23.47596  55.04997  1.000 61.72019  ? 155 PHE C O   1 
ATOM   4906 C  CB  . PHE D 1 175 ? -34.79248 20.98285  53.90743  1.000 50.81870  ? 155 PHE C CB  1 
ATOM   4907 C  CG  . PHE D 1 175 ? -35.72739 19.91975  53.39785  1.000 48.76098  ? 155 PHE C CG  1 
ATOM   4908 C  CD1 . PHE D 1 175 ? -36.54119 20.15857  52.30058  1.000 41.61692  ? 155 PHE C CD1 1 
ATOM   4909 C  CD2 . PHE D 1 175 ? -35.78948 18.67937  54.01396  1.000 46.93789  ? 155 PHE C CD2 1 
ATOM   4910 C  CE1 . PHE D 1 175 ? -37.39959 19.18189  51.83008  1.000 39.15551  ? 155 PHE C CE1 1 
ATOM   4911 C  CE2 . PHE D 1 175 ? -36.64531 17.69876  53.54706  1.000 44.60686  ? 155 PHE C CE2 1 
ATOM   4912 C  CZ  . PHE D 1 175 ? -37.45079 17.95146  52.45409  1.000 43.14955  ? 155 PHE C CZ  1 
ATOM   4913 N  N   . VAL D 1 176 ? -34.53390 22.69518  56.93954  1.000 55.68829  ? 156 VAL C N   1 
ATOM   4914 C  CA  . VAL D 1 176 ? -33.65487 23.40218  57.86360  1.000 51.94518  ? 156 VAL C CA  1 
ATOM   4915 C  C   . VAL D 1 176 ? -32.67611 22.40740  58.47098  1.000 47.65699  ? 156 VAL C C   1 
ATOM   4916 O  O   . VAL D 1 176 ? -33.06267 21.29908  58.85793  1.000 52.73665  ? 156 VAL C O   1 
ATOM   4917 C  CB  . VAL D 1 176 ? -34.46842 24.12408  58.95472  1.000 45.75718  ? 156 VAL C CB  1 
ATOM   4918 C  CG1 . VAL D 1 176 ? -33.56253 24.62093  60.06086  1.000 51.69034  ? 156 VAL C CG1 1 
ATOM   4919 C  CG2 . VAL D 1 176 ? -35.24884 25.27858  58.34779  1.000 48.71280  ? 156 VAL C CG2 1 
ATOM   4920 N  N   . GLN D 1 177 ? -31.40652 22.80051  58.54634  1.000 50.09615  ? 157 GLN C N   1 
ATOM   4921 C  CA  . GLN D 1 177 ? -30.38400 21.93847  59.12166  1.000 56.39556  ? 157 GLN C CA  1 
ATOM   4922 C  C   . GLN D 1 177 ? -30.45677 21.95174  60.64280  1.000 68.19122  ? 157 GLN C C   1 
ATOM   4923 O  O   . GLN D 1 177 ? -30.65228 23.00103  61.26301  1.000 64.47913  ? 157 GLN C O   1 
ATOM   4924 C  CB  . GLN D 1 177 ? -28.98873 22.37160  58.67038  1.000 53.83782  ? 157 GLN C CB  1 
ATOM   4925 C  CG  . GLN D 1 177 ? -27.87195 21.52867  59.27424  1.000 59.36611  ? 157 GLN C CG  1 
ATOM   4926 C  CD  . GLN D 1 177 ? -26.50119 21.89092  58.74461  1.000 55.79897  ? 157 GLN C CD  1 
ATOM   4927 O  OE1 . GLN D 1 177 ? -26.37168 22.51030  57.68847  1.000 62.21844  ? 157 GLN C OE1 1 
ATOM   4928 N  NE2 . GLN D 1 177 ? -25.46537 21.50400  59.47936  1.000 59.58430  ? 157 GLN C NE2 1 
ATOM   4929 N  N   . HIS D 1 178 ? -30.29630 20.77233  61.24070  1.000 68.63781  ? 158 HIS C N   1 
ATOM   4930 C  CA  . HIS D 1 178 ? -30.28983 20.61113  62.68907  1.000 65.63467  ? 158 HIS C CA  1 
ATOM   4931 C  C   . HIS D 1 178 ? -29.09790 19.75197  63.07907  1.000 73.37908  ? 158 HIS C C   1 
ATOM   4932 O  O   . HIS D 1 178 ? -29.02689 18.57794  62.70186  1.000 72.10142  ? 158 HIS C O   1 
ATOM   4933 C  CB  . HIS D 1 178 ? -31.59995 19.98828  63.17614  1.000 68.97583  ? 158 HIS C CB  1 
ATOM   4934 C  CG  . HIS D 1 178 ? -32.78935 20.87196  62.97236  1.000 65.79749  ? 158 HIS C CG  1 
ATOM   4935 N  ND1 . HIS D 1 178 ? -33.38540 21.56575  64.00298  1.000 70.84323  ? 158 HIS C ND1 1 
ATOM   4936 C  CD2 . HIS D 1 178 ? -33.47834 21.19546  61.85255  1.000 66.17972  ? 158 HIS C CD2 1 
ATOM   4937 C  CE1 . HIS D 1 178 ? -34.39551 22.27243  63.52821  1.000 74.44507  ? 158 HIS C CE1 1 
ATOM   4938 N  NE2 . HIS D 1 178 ? -34.47569 22.06279  62.22652  1.000 67.87192  ? 158 HIS C NE2 1 
ATOM   4939 N  N   . GLY D 1 179 ? -28.16612 20.33770  63.82759  1.000 75.87161  ? 159 GLY C N   1 
ATOM   4940 C  CA  . GLY D 1 179 ? -26.95561 19.65685  64.21646  1.000 70.83007  ? 159 GLY C CA  1 
ATOM   4941 C  C   . GLY D 1 179 ? -25.75469 20.16855  63.44854  1.000 67.47257  ? 159 GLY C C   1 
ATOM   4942 O  O   . GLY D 1 179 ? -25.88598 20.90921  62.46731  1.000 69.97282  ? 159 GLY C O   1 
ATOM   4943 N  N   . PRO D 1 180 ? -24.55645 19.78353  63.88026  1.000 68.46908  ? 160 PRO C N   1 
ATOM   4944 C  CA  . PRO D 1 180 ? -23.34216 20.23252  63.19010  1.000 69.60217  ? 160 PRO C CA  1 
ATOM   4945 C  C   . PRO D 1 180 ? -23.20052 19.57700  61.82388  1.000 61.62214  ? 160 PRO C C   1 
ATOM   4946 O  O   . PRO D 1 180 ? -23.98954 18.71840  61.42040  1.000 66.99143  ? 160 PRO C O   1 
ATOM   4947 C  CB  . PRO D 1 180 ? -22.21843 19.80335  64.13708  1.000 65.06973  ? 160 PRO C CB  1 
ATOM   4948 C  CG  . PRO D 1 180 ? -22.78331 18.63376  64.86858  1.000 68.78280  ? 160 PRO C CG  1 
ATOM   4949 C  CD  . PRO D 1 180 ? -24.25131 18.91835  65.03362  1.000 69.77851  ? 160 PRO C CD  1 
ATOM   4950 N  N   . THR D 1 181 ? -22.17219 20.01508  61.09905  1.000 64.15334  ? 161 THR C N   1 
ATOM   4951 C  CA  . THR D 1 181 ? -21.79670 19.38882  59.84101  1.000 57.30974  ? 161 THR C CA  1 
ATOM   4952 C  C   . THR D 1 181 ? -20.80555 18.26905  60.12837  1.000 60.96127  ? 161 THR C C   1 
ATOM   4953 O  O   . THR D 1 181 ? -19.83745 18.46280  60.86963  1.000 66.97444  ? 161 THR C O   1 
ATOM   4954 C  CB  . THR D 1 181 ? -21.19229 20.41245  58.87921  1.000 63.58746  ? 161 THR C CB  1 
ATOM   4955 O  OG1 . THR D 1 181 ? -22.12164 21.48370  58.66909  1.000 61.22796  ? 161 THR C OG1 1 
ATOM   4956 C  CG2 . THR D 1 181 ? -20.87029 19.76126  57.53865  1.000 56.44397  ? 161 THR C CG2 1 
ATOM   4957 N  N   . LEU D 1 182 ? -21.05035 17.10270  59.54460  1.000 61.06702  ? 162 LEU C N   1 
ATOM   4958 C  CA  . LEU D 1 182 ? -20.30764 15.89343  59.86253  1.000 55.57359  ? 162 LEU C CA  1 
ATOM   4959 C  C   . LEU D 1 182 ? -19.37710 15.52456  58.71456  1.000 64.26592  ? 162 LEU C C   1 
ATOM   4960 O  O   . LEU D 1 182 ? -19.74796 15.62832  57.54049  1.000 68.04389  ? 162 LEU C O   1 
ATOM   4961 C  CB  . LEU D 1 182 ? -21.26464 14.73272  60.15780  1.000 61.48643  ? 162 LEU C CB  1 
ATOM   4962 C  CG  . LEU D 1 182 ? -21.92195 14.63935  61.54279  1.000 57.24139  ? 162 LEU C CG  1 
ATOM   4963 C  CD1 . LEU D 1 182 ? -22.74804 15.86825  61.89651  1.000 66.29784  ? 162 LEU C CD1 1 
ATOM   4964 C  CD2 . LEU D 1 182 ? -22.78508 13.39394  61.62385  1.000 56.68241  ? 162 LEU C CD2 1 
ATOM   4965 N  N   . SER D 1 183 ? -18.16714 15.09542  59.06269  1.000 67.19292  ? 163 SER C N   1 
ATOM   4966 C  CA  . SER D 1 183 ? -17.18582 14.61500  58.10156  1.000 67.51920  ? 163 SER C CA  1 
ATOM   4967 C  C   . SER D 1 183 ? -16.87878 13.15144  58.38126  1.000 80.19587  ? 163 SER C C   1 
ATOM   4968 O  O   . SER D 1 183 ? -16.85850 12.72257  59.53940  1.000 78.34366  ? 163 SER C O   1 
ATOM   4969 C  CB  . SER D 1 183 ? -15.89297 15.43735  58.15840  1.000 68.16528  ? 163 SER C CB  1 
ATOM   4970 O  OG  . SER D 1 183 ? -16.10215 16.75675  57.68867  1.000 68.14519  ? 163 SER C OG  1 
ATOM   4971 N  N   . ASP D 1 184 ? -16.64356 12.38707  57.31713  1.000 77.27906  ? 164 ASP C N   1 
ATOM   4972 C  CA  . ASP D 1 184 ? -16.32138 10.97169  57.43335  1.000 86.21647  ? 164 ASP C CA  1 
ATOM   4973 C  C   . ASP D 1 184 ? -14.82345 10.71828  57.55162  1.000 91.08872  ? 164 ASP C C   1 
ATOM   4974 O  O   . ASP D 1 184 ? -14.38733 9.57007   57.41541  1.000 95.79716  ? 164 ASP C O   1 
ATOM   4975 C  CB  . ASP D 1 184 ? -16.88660 10.20010  56.23637  1.000 81.38051  ? 164 ASP C CB  1 
ATOM   4976 C  CG  . ASP D 1 184 ? -16.17976 10.53615  54.93545  1.000 78.96681  ? 164 ASP C CG  1 
ATOM   4977 O  OD1 . ASP D 1 184 ? -15.66911 11.66838  54.80443  1.000 82.43901  ? 164 ASP C OD1 1 
ATOM   4978 O  OD2 . ASP D 1 184 ? -16.13588 9.66513   54.04095  1.000 82.58631  ? 164 ASP C OD2 1 
ATOM   4979 N  N   . GLY D 1 185 ? -14.02929 11.76027  57.80101  1.000 82.48175  ? 165 GLY C N   1 
ATOM   4980 C  CA  . GLY D 1 185 ? -12.59089 11.63721  57.86691  1.000 87.71383  ? 165 GLY C CA  1 
ATOM   4981 C  C   . GLY D 1 185 ? -11.89135 11.56181  56.52901  1.000 90.66608  ? 165 GLY C C   1 
ATOM   4982 O  O   . GLY D 1 185 ? -10.66820 11.73990  56.47535  1.000 95.95065  ? 165 GLY C O   1 
ATOM   4983 N  N   . GLN D 1 186 ? -12.62395 11.30740  55.44413  1.000 89.69996  ? 166 GLN C N   1 
ATOM   4984 C  CA  . GLN D 1 186 ? -12.04533 11.21713  54.11307  1.000 83.12168  ? 166 GLN C CA  1 
ATOM   4985 C  C   . GLN D 1 186 ? -12.34099 12.42958  53.24300  1.000 85.26153  ? 166 GLN C C   1 
ATOM   4986 O  O   . GLN D 1 186 ? -11.80125 12.51922  52.13450  1.000 78.99722  ? 166 GLN C O   1 
ATOM   4987 C  CB  . GLN D 1 186 ? -12.54916 9.95240   53.40185  1.000 82.38586  ? 166 GLN C CB  1 
ATOM   4988 C  CG  . GLN D 1 186 ? -12.57603 8.71851   54.28860  1.000 84.10366  ? 166 GLN C CG  1 
ATOM   4989 C  CD  . GLN D 1 186 ? -12.98030 7.46706   53.53591  1.000 84.37222  ? 166 GLN C CD  1 
ATOM   4990 O  OE1 . GLN D 1 186 ? -14.14699 7.07253   53.54268  1.000 74.82635  ? 166 GLN C OE1 1 
ATOM   4991 N  NE2 . GLN D 1 186 ? -12.01319 6.83240   52.88321  1.000 73.01491  ? 166 GLN C NE2 1 
ATOM   4992 N  N   . GLY D 1 187 ? -13.18028 13.35249  53.70347  1.000 78.49802  ? 167 GLY C N   1 
ATOM   4993 C  CA  . GLY D 1 187 ? -13.48619 14.56613  52.96824  1.000 71.41396  ? 167 GLY C CA  1 
ATOM   4994 C  C   . GLY D 1 187 ? -14.93863 14.73567  52.57598  1.000 67.45533  ? 167 GLY C C   1 
ATOM   4995 O  O   . GLY D 1 187 ? -15.30994 15.82528  52.11389  1.000 74.26984  ? 167 GLY C O   1 
ATOM   4996 N  N   . ARG D 1 188 ? -15.78703 13.72180  52.73074  1.000 67.35063  ? 168 ARG C N   1 
ATOM   4997 C  CA  . ARG D 1 188 ? -17.18565 13.82974  52.33403  1.000 72.48560  ? 168 ARG C CA  1 
ATOM   4998 C  C   . ARG D 1 188 ? -17.99628 14.37640  53.50265  1.000 71.14227  ? 168 ARG C C   1 
ATOM   4999 O  O   . ARG D 1 188 ? -18.00614 13.78813  54.58935  1.000 69.97661  ? 168 ARG C O   1 
ATOM   5000 C  CB  . ARG D 1 188 ? -17.74214 12.48176  51.87614  1.000 71.72971  ? 168 ARG C CB  1 
ATOM   5001 C  CG  . ARG D 1 188 ? -18.82003 12.61654  50.80853  1.000 72.70914  ? 168 ARG C CG  1 
ATOM   5002 C  CD  . ARG D 1 188 ? -19.77471 11.43426  50.78797  1.000 73.81002  ? 168 ARG C CD  1 
ATOM   5003 N  NE  . ARG D 1 188 ? -20.86097 11.65171  49.83947  1.000 70.00024  ? 168 ARG C NE  1 
ATOM   5004 C  CZ  . ARG D 1 188 ? -21.95745 12.35091  50.10323  1.000 65.31684  ? 168 ARG C CZ  1 
ATOM   5005 N  NH1 . ARG D 1 188 ? -22.15808 12.90255  51.28933  1.000 59.75153  ? 168 ARG C NH1 1 
ATOM   5006 N  NH2 . ARG D 1 188 ? -22.87547 12.50302  49.15232  1.000 58.01884  ? 168 ARG C NH2 1 
ATOM   5007 N  N   . ARG D 1 189 ? -18.67487 15.49460  53.27558  1.000 66.59352  ? 169 ARG C N   1 
ATOM   5008 C  CA  . ARG D 1 189 ? -19.43221 16.18118  54.30930  1.000 59.17565  ? 169 ARG C CA  1 
ATOM   5009 C  C   . ARG D 1 189 ? -20.91290 15.84974  54.17651  1.000 59.44080  ? 169 ARG C C   1 
ATOM   5010 O  O   . ARG D 1 189 ? -21.39712 15.51319  53.09390  1.000 59.87117  ? 169 ARG C O   1 
ATOM   5011 C  CB  . ARG D 1 189 ? -19.21207 17.69362  54.21663  1.000 58.22148  ? 169 ARG C CB  1 
ATOM   5012 C  CG  . ARG D 1 189 ? -17.74014 18.07791  54.21563  1.000 59.30675  ? 169 ARG C CG  1 
ATOM   5013 C  CD  . ARG D 1 189 ? -17.50378 19.51539  53.77832  1.000 53.92849  ? 169 ARG C CD  1 
ATOM   5014 N  NE  . ARG D 1 189 ? -17.95975 20.48705  54.76507  1.000 72.59514  ? 169 ARG C NE  1 
ATOM   5015 C  CZ  . ARG D 1 189 ? -18.82623 21.45875  54.51582  1.000 72.45712  ? 169 ARG C CZ  1 
ATOM   5016 N  NH1 . ARG D 1 189 ? -19.33921 21.63340  53.30979  1.000 63.51604  ? 169 ARG C NH1 1 
ATOM   5017 N  NH2 . ARG D 1 189 ? -19.17918 22.28153  55.49943  1.000 66.76207  ? 169 ARG C NH2 1 
ATOM   5018 N  N   . ARG D 1 190 ? -21.63033 15.93758  55.29175  1.000 49.06781  ? 170 ARG C N   1 
ATOM   5019 C  CA  . ARG D 1 190 ? -23.04227 15.58957  55.28634  1.000 53.67103  ? 170 ARG C CA  1 
ATOM   5020 C  C   . ARG D 1 190 ? -23.74371 16.32228  56.42211  1.000 50.80659  ? 170 ARG C C   1 
ATOM   5021 O  O   . ARG D 1 190 ? -23.15380 16.57331  57.47428  1.000 49.12530  ? 170 ARG C O   1 
ATOM   5022 C  CB  . ARG D 1 190 ? -23.23311 14.07368  55.40739  1.000 61.37712  ? 170 ARG C CB  1 
ATOM   5023 C  CG  . ARG D 1 190 ? -22.51461 13.46243  56.59623  1.000 66.97605  ? 170 ARG C CG  1 
ATOM   5024 C  CD  . ARG D 1 190 ? -22.69979 11.95680  56.65056  1.000 70.87600  ? 170 ARG C CD  1 
ATOM   5025 N  NE  . ARG D 1 190 ? -22.75826 11.47428  58.02567  1.000 84.52608  ? 170 ARG C NE  1 
ATOM   5026 C  CZ  . ARG D 1 190 ? -21.69839 11.21660  58.77997  1.000 79.94041  ? 170 ARG C CZ  1 
ATOM   5027 N  NH1 . ARG D 1 190 ? -20.46818 11.40155  58.33082  1.000 74.67155  ? 170 ARG C NH1 1 
ATOM   5028 N  NH2 . ARG D 1 190 ? -21.87768 10.75942  60.01594  1.000 71.33265  ? 170 ARG C NH2 1 
ATOM   5029 N  N   . VAL D 1 191 ? -25.01291 16.66495  56.19227  1.000 42.78812  ? 171 VAL C N   1 
ATOM   5030 C  CA  . VAL D 1 191 ? -25.81181 17.44340  57.13065  1.000 41.33543  ? 171 VAL C CA  1 
ATOM   5031 C  C   . VAL D 1 191 ? -27.19761 16.81944  57.24846  1.000 49.25235  ? 171 VAL C C   1 
ATOM   5032 O  O   . VAL D 1 191 ? -27.65453 16.09105  56.36438  1.000 47.31699  ? 171 VAL C O   1 
ATOM   5033 C  CB  . VAL D 1 191 ? -25.92597 18.92375  56.69946  1.000 47.53720  ? 171 VAL C CB  1 
ATOM   5034 C  CG1 . VAL D 1 191 ? -24.58682 19.62602  56.85454  1.000 49.69104  ? 171 VAL C CG1 1 
ATOM   5035 C  CG2 . VAL D 1 191 ? -26.40077 19.01736  55.26189  1.000 43.41427  ? 171 VAL C CG2 1 
ATOM   5036 N  N   . HIS D 1 192 ? -27.87022 17.12115  58.35997  1.000 49.48578  ? 172 HIS C N   1 
ATOM   5037 C  CA  . HIS D 1 192 ? -29.18815 16.57399  58.67074  1.000 51.36311  ? 172 HIS C CA  1 
ATOM   5038 C  C   . HIS D 1 192 ? -30.23450 17.68185  58.58457  1.000 49.86313  ? 172 HIS C C   1 
ATOM   5039 O  O   . HIS D 1 192 ? -30.15878 18.66977  59.32189  1.000 50.89924  ? 172 HIS C O   1 
ATOM   5040 C  CB  . HIS D 1 192 ? -29.19807 15.92885  60.05828  1.000 48.67016  ? 172 HIS C CB  1 
ATOM   5041 C  CG  . HIS D 1 192 ? -28.32204 14.71907  60.17189  1.000 56.94559  ? 172 HIS C CG  1 
ATOM   5042 N  ND1 . HIS D 1 192 ? -28.10283 13.85702  59.11836  1.000 66.38007  ? 172 HIS C ND1 1 
ATOM   5043 C  CD2 . HIS D 1 192 ? -27.60915 14.22866  61.21397  1.000 60.16988  ? 172 HIS C CD2 1 
ATOM   5044 C  CE1 . HIS D 1 192 ? -27.29436 12.88700  59.50660  1.000 65.11145  ? 172 HIS C CE1 1 
ATOM   5045 N  NE2 . HIS D 1 192 ? -26.97980 13.08930  60.77374  1.000 71.11145  ? 172 HIS C NE2 1 
ATOM   5046 N  N   . LEU D 1 193 ? -31.21280 17.50783  57.69543  1.000 50.76286  ? 173 LEU C N   1 
ATOM   5047 C  CA  . LEU D 1 193 ? -32.25545 18.48820  57.42700  1.000 51.55140  ? 173 LEU C CA  1 
ATOM   5048 C  C   . LEU D 1 193 ? -33.60970 17.97410  57.89775  1.000 46.74649  ? 173 LEU C C   1 
ATOM   5049 O  O   . LEU D 1 193 ? -33.88434 16.76833  57.86515  1.000 52.49350  ? 173 LEU C O   1 
ATOM   5050 C  CB  . LEU D 1 193 ? -32.34830 18.81998  55.93291  1.000 46.75292  ? 173 LEU C CB  1 
ATOM   5051 C  CG  . LEU D 1 193 ? -31.26976 19.61876  55.19071  1.000 51.98500  ? 173 LEU C CG  1 
ATOM   5052 C  CD1 . LEU D 1 193 ? -31.15596 21.02671  55.73349  1.000 54.82339  ? 173 LEU C CD1 1 
ATOM   5053 C  CD2 . LEU D 1 193 ? -29.91945 18.92219  55.21235  1.000 46.70836  ? 173 LEU C CD2 1 
ATOM   5054 N  N   . HIS D 1 194 ? -34.46607 18.91841  58.29044  1.000 49.25255  ? 174 HIS C N   1 
ATOM   5055 C  CA  . HIS D 1 194 ? -35.81428 18.64185  58.76283  1.000 48.53784  ? 174 HIS C CA  1 
ATOM   5056 C  C   . HIS D 1 194 ? -36.77193 19.63971  58.13021  1.000 53.35314  ? 174 HIS C C   1 
ATOM   5057 O  O   . HIS D 1 194 ? -36.46996 20.83428  58.05480  1.000 56.10565  ? 174 HIS C O   1 
ATOM   5058 C  CB  . HIS D 1 194 ? -35.88850 18.72882  60.29552  1.000 58.84869  ? 174 HIS C CB  1 
ATOM   5059 C  CG  . HIS D 1 194 ? -37.28337 18.80882  60.83723  1.000 61.78637  ? 174 HIS C CG  1 
ATOM   5060 N  ND1 . HIS D 1 194 ? -38.00778 19.98215  60.86518  1.000 59.87727  ? 174 HIS C ND1 1 
ATOM   5061 C  CD2 . HIS D 1 194 ? -38.07918 17.86354  61.39091  1.000 63.99257  ? 174 HIS C CD2 1 
ATOM   5062 C  CE1 . HIS D 1 194 ? -39.19413 19.75294  61.39903  1.000 59.95511  ? 174 HIS C CE1 1 
ATOM   5063 N  NE2 . HIS D 1 194 ? -39.26196 18.47569  61.72850  1.000 65.64102  ? 174 HIS C NE2 1 
ATOM   5064 N  N   . LYS D 1 195 ? -37.92306 19.14564  57.67701  1.000 52.20574  ? 175 LYS C N   1 
ATOM   5065 C  CA  . LYS D 1 195 ? -38.98420 19.98481  57.13623  1.000 55.61467  ? 175 LYS C CA  1 
ATOM   5066 C  C   . LYS D 1 195 ? -40.30150 19.58999  57.78438  1.000 59.52660  ? 175 LYS C C   1 
ATOM   5067 O  O   . LYS D 1 195 ? -40.65753 18.40736  57.80366  1.000 60.78718  ? 175 LYS C O   1 
ATOM   5068 C  CB  . LYS D 1 195 ? -39.08714 19.85786  55.61152  1.000 48.36178  ? 175 LYS C CB  1 
ATOM   5069 C  CG  . LYS D 1 195 ? -40.28675 20.58960  55.02157  1.000 50.31807  ? 175 LYS C CG  1 
ATOM   5070 C  CD  . LYS D 1 195 ? -40.38090 20.40228  53.51801  1.000 51.62725  ? 175 LYS C CD  1 
ATOM   5071 C  CE  . LYS D 1 195 ? -41.66329 21.01376  52.96815  1.000 45.06215  ? 175 LYS C CE  1 
ATOM   5072 N  NZ  . LYS D 1 195 ? -41.73891 22.48499  53.17944  1.000 48.35010  ? 175 LYS C NZ  1 
ATOM   5073 N  N   . SER D 1 196 ? -41.01481 20.57689  58.31994  1.000 62.72552  ? 176 SER C N   1 
ATOM   5074 C  CA  . SER D 1 196 ? -42.30971 20.31766  58.93213  1.000 63.37715  ? 176 SER C CA  1 
ATOM   5075 C  C   . SER D 1 196 ? -43.34701 20.00308  57.86112  1.000 58.33411  ? 176 SER C C   1 
ATOM   5076 O  O   . SER D 1 196 ? -43.33206 20.58063  56.77071  1.000 64.59976  ? 176 SER C O   1 
ATOM   5077 C  CB  . SER D 1 196 ? -42.75015 21.52147  59.76189  1.000 69.61214  ? 176 SER C CB  1 
ATOM   5078 O  OG  . SER D 1 196 ? -41.73093 21.90653  60.66981  1.000 69.63195  ? 176 SER C OG  1 
ATOM   5079 N  N   . LEU D 1 197 ? -44.25505 19.08278  58.17759  1.000 63.00288  ? 177 LEU C N   1 
ATOM   5080 C  CA  . LEU D 1 197 ? -45.24219 18.59965  57.22440  1.000 70.34119  ? 177 LEU C CA  1 
ATOM   5081 C  C   . LEU D 1 197 ? -46.65676 18.82769  57.73820  1.000 79.63677  ? 177 LEU C C   1 
ATOM   5082 O  O   . LEU D 1 197 ? -46.90656 18.81524  58.94781  1.000 85.96094  ? 177 LEU C O   1 
ATOM   5083 C  CB  . LEU D 1 197 ? -45.05237 17.10584  56.93677  1.000 65.86596  ? 177 LEU C CB  1 
ATOM   5084 C  CG  . LEU D 1 197 ? -43.77744 16.66351  56.22295  1.000 58.38494  ? 177 LEU C CG  1 
ATOM   5085 C  CD1 . LEU D 1 197 ? -43.77691 15.15618  56.08371  1.000 60.10362  ? 177 LEU C CD1 1 
ATOM   5086 C  CD2 . LEU D 1 197 ? -43.65858 17.32724  54.86198  1.000 45.72172  ? 177 LEU C CD2 1 
ATOM   5087 N  N   . ARG D 1 198 ? -47.57410 19.03985  56.79566  1.000 85.70869  ? 178 ARG C N   1 
ATOM   5088 C  CA  . ARG D 1 198 ? -49.01511 19.02543  57.05084  1.000 89.05412  ? 178 ARG C CA  1 
ATOM   5089 C  C   . ARG D 1 198 ? -49.46712 20.09283  58.05047  1.000 97.91770  ? 178 ARG C C   1 
ATOM   5090 O  O   . ARG D 1 198 ? -50.64481 20.16871  58.40499  1.000 93.01765  ? 178 ARG C O   1 
ATOM   5091 C  CB  . ARG D 1 198 ? -49.43773 17.63471  57.53635  1.000 80.75392  ? 178 ARG C CB  1 
ATOM   5092 C  CG  . ARG D 1 198 ? -50.83161 17.20647  57.11089  1.000 81.39208  ? 178 ARG C CG  1 
ATOM   5093 C  CD  . ARG D 1 198 ? -50.99738 15.70170  57.26163  1.000 81.14046  ? 178 ARG C CD  1 
ATOM   5094 N  NE  . ARG D 1 198 ? -52.36160 15.26151  56.99448  1.000 88.26090  ? 178 ARG C NE  1 
ATOM   5095 C  CZ  . ARG D 1 198 ? -52.83625 14.97469  55.78980  1.000 87.45485  ? 178 ARG C CZ  1 
ATOM   5096 N  NH1 . ARG D 1 198 ? -52.08710 15.09071  54.70546  1.000 85.09529  ? 178 ARG C NH1 1 
ATOM   5097 N  NH2 . ARG D 1 198 ? -54.09507 14.56236  55.66976  1.000 80.96334  ? 178 ARG C NH2 1 
ATOM   5098 N  N   . ALA E 1 34  ? -3.93700  -0.78742  59.72183  1.000 63.13267  ? 14  ALA E N   1 
ATOM   5099 C  CA  . ALA E 1 34  ? -3.39471  -2.08051  60.11551  1.000 71.85155  ? 14  ALA E CA  1 
ATOM   5100 C  C   . ALA E 1 34  ? -4.44906  -3.17559  59.97102  1.000 76.35902  ? 14  ALA E C   1 
ATOM   5101 O  O   . ALA E 1 34  ? -4.32190  -4.05821  59.12143  1.000 81.69087  ? 14  ALA E O   1 
ATOM   5102 C  CB  . ALA E 1 34  ? -2.87761  -2.02673  61.54208  1.000 77.68845  ? 14  ALA E CB  1 
ATOM   5103 N  N   . TRP E 1 35  ? -5.48376  -3.11143  60.80739  1.000 71.96794  ? 15  TRP E N   1 
ATOM   5104 C  CA  . TRP E 1 35  ? -6.61601  -4.02855  60.74359  1.000 62.76998  ? 15  TRP E CA  1 
ATOM   5105 C  C   . TRP E 1 35  ? -7.74198  -3.35388  59.97075  1.000 62.25231  ? 15  TRP E C   1 
ATOM   5106 O  O   . TRP E 1 35  ? -8.28251  -2.33578  60.41807  1.000 68.94061  ? 15  TRP E O   1 
ATOM   5107 C  CB  . TRP E 1 35  ? -7.08208  -4.42060  62.14523  1.000 56.31710  ? 15  TRP E CB  1 
ATOM   5108 C  CG  . TRP E 1 35  ? -6.02249  -5.08158  62.97686  1.000 62.63771  ? 15  TRP E CG  1 
ATOM   5109 C  CD1 . TRP E 1 35  ? -5.06784  -4.46256  63.73259  1.000 57.29556  ? 15  TRP E CD1 1 
ATOM   5110 C  CD2 . TRP E 1 35  ? -5.81366  -6.49110  63.14343  1.000 58.36308  ? 15  TRP E CD2 1 
ATOM   5111 N  NE1 . TRP E 1 35  ? -4.27759  -5.39896  64.35624  1.000 65.15115  ? 15  TRP E NE1 1 
ATOM   5112 C  CE2 . TRP E 1 35  ? -4.71441  -6.65123  64.01124  1.000 65.34678  ? 15  TRP E CE2 1 
ATOM   5113 C  CE3 . TRP E 1 35  ? -6.44837  -7.63175  62.64247  1.000 58.72250  ? 15  TRP E CE3 1 
ATOM   5114 C  CZ2 . TRP E 1 35  ? -4.23657  -7.90636  64.38879  1.000 53.53568  ? 15  TRP E CZ2 1 
ATOM   5115 C  CZ3 . TRP E 1 35  ? -5.97253  -8.87752  63.01895  1.000 57.33833  ? 15  TRP E CZ3 1 
ATOM   5116 C  CH2 . TRP E 1 35  ? -4.87768  -9.00378  63.88360  1.000 49.51680  ? 15  TRP E CH2 1 
ATOM   5117 N  N   . GLN E 1 36  ? -8.09142  -3.91680  58.81571  1.000 66.74198  ? 16  GLN E N   1 
ATOM   5118 C  CA  . GLN E 1 36  ? -9.07528  -3.31546  57.92540  1.000 66.13310  ? 16  GLN E CA  1 
ATOM   5119 C  C   . GLN E 1 36  ? -10.10934 -4.35481  57.52037  1.000 58.33065  ? 16  GLN E C   1 
ATOM   5120 O  O   . GLN E 1 36  ? -9.75290  -5.45998  57.10370  1.000 55.82121  ? 16  GLN E O   1 
ATOM   5121 C  CB  . GLN E 1 36  ? -8.39582  -2.73388  56.68030  1.000 71.01062  ? 16  GLN E CB  1 
ATOM   5122 C  CG  . GLN E 1 36  ? -7.38138  -1.64430  56.98261  1.000 84.21262  ? 16  GLN E CG  1 
ATOM   5123 C  CD  . GLN E 1 36  ? -6.52427  -1.29063  55.78135  1.000 99.75299  ? 16  GLN E CD  1 
ATOM   5124 O  OE1 . GLN E 1 36  ? -6.79312  -1.72230  54.65981  1.000 95.84578  ? 16  GLN E OE1 1 
ATOM   5125 N  NE2 . GLN E 1 36  ? -5.47974  -0.50315  56.01395  1.000 96.32308  ? 16  GLN E NE2 1 
ATOM   5126 N  N   . TRP E 1 37  ? -11.38304 -4.00039  57.62950  1.000 47.72689  ? 17  TRP E N   1 
ATOM   5127 C  CA  . TRP E 1 37  ? -12.46230 -4.88877  57.22963  1.000 46.90400  ? 17  TRP E CA  1 
ATOM   5128 C  C   . TRP E 1 37  ? -12.89175 -4.58654  55.80040  1.000 54.13191  ? 17  TRP E C   1 
ATOM   5129 O  O   . TRP E 1 37  ? -12.77260 -3.45516  55.32253  1.000 56.93154  ? 17  TRP E O   1 
ATOM   5130 C  CB  . TRP E 1 37  ? -13.66000 -4.75688  58.17145  1.000 45.14802  ? 17  TRP E CB  1 
ATOM   5131 C  CG  . TRP E 1 37  ? -13.47688 -5.48803  59.45753  1.000 50.87584  ? 17  TRP E CG  1 
ATOM   5132 C  CD1 . TRP E 1 37  ? -13.01703 -4.97561  60.63556  1.000 45.16315  ? 17  TRP E CD1 1 
ATOM   5133 C  CD2 . TRP E 1 37  ? -13.73985 -6.87514  59.69748  1.000 47.72584  ? 17  TRP E CD2 1 
ATOM   5134 N  NE1 . TRP E 1 37  ? -12.98251 -5.95762  61.59613  1.000 42.47113  ? 17  TRP E NE1 1 
ATOM   5135 C  CE2 . TRP E 1 37  ? -13.42119 -7.13341  61.04505  1.000 51.34813  ? 17  TRP E CE2 1 
ATOM   5136 C  CE3 . TRP E 1 37  ? -14.21568 -7.92284  58.90380  1.000 41.23924  ? 17  TRP E CE3 1 
ATOM   5137 C  CZ2 . TRP E 1 37  ? -13.56252 -8.39645  61.61576  1.000 43.52846  ? 17  TRP E CZ2 1 
ATOM   5138 C  CZ3 . TRP E 1 37  ? -14.35666 -9.17440  59.47149  1.000 34.92959  ? 17  TRP E CZ3 1 
ATOM   5139 C  CH2 . TRP E 1 37  ? -14.03180 -9.40021  60.81484  1.000 42.61636  ? 17  TRP E CH2 1 
ATOM   5140 N  N   . GLU E 1 38  ? -13.38992 -5.61525  55.11739  1.000 53.49195  ? 18  GLU E N   1 
ATOM   5141 C  CA  . GLU E 1 38  ? -13.86184 -5.44503  53.75175  1.000 44.23075  ? 18  GLU E CA  1 
ATOM   5142 C  C   . GLU E 1 38  ? -14.97401 -6.44437  53.47455  1.000 40.85638  ? 18  GLU E C   1 
ATOM   5143 O  O   . GLU E 1 38  ? -15.09599 -7.47219  54.14531  1.000 44.91702  ? 18  GLU E O   1 
ATOM   5144 C  CB  . GLU E 1 38  ? -12.72589 -5.62441  52.73265  1.000 45.08889  ? 18  GLU E CB  1 
ATOM   5145 C  CG  . GLU E 1 38  ? -12.32816 -7.07972  52.49976  1.000 50.60485  ? 18  GLU E CG  1 
ATOM   5146 C  CD  . GLU E 1 38  ? -11.11474 -7.23266  51.59696  1.000 50.94956  ? 18  GLU E CD  1 
ATOM   5147 O  OE1 . GLU E 1 38  ? -10.11111 -6.51985  51.80879  1.000 55.73779  ? 18  GLU E OE1 1 
ATOM   5148 O  OE2 . GLU E 1 38  ? -11.16360 -8.06819  50.66980  1.000 56.00293  ? 18  GLU E OE2 1 
ATOM   5149 N  N   . VAL E 1 39  ? -15.79523 -6.12236  52.47952  1.000 41.35364  ? 19  VAL E N   1 
ATOM   5150 C  CA  . VAL E 1 39  ? -16.71410 -7.09524  51.89910  1.000 42.52704  ? 19  VAL E CA  1 
ATOM   5151 C  C   . VAL E 1 39  ? -15.93790 -7.84029  50.81740  1.000 45.88832  ? 19  VAL E C   1 
ATOM   5152 O  O   . VAL E 1 39  ? -15.54150 -7.25200  49.80822  1.000 50.24086  ? 19  VAL E O   1 
ATOM   5153 C  CB  . VAL E 1 39  ? -17.97129 -6.42552  51.33370  1.000 41.65765  ? 19  VAL E CB  1 
ATOM   5154 C  CG1 . VAL E 1 39  ? -18.92453 -7.47370  50.77136  1.000 36.17591  ? 19  VAL E CG1 1 
ATOM   5155 C  CG2 . VAL E 1 39  ? -18.65863 -5.60210  52.41338  1.000 39.78139  ? 19  VAL E CG2 1 
ATOM   5156 N  N   . SER E 1 40  ? -15.69822 -9.13066  51.03822  1.000 43.57212  ? 20  SER E N   1 
ATOM   5157 C  CA  . SER E 1 40  ? -14.77027 -9.87215  50.19489  1.000 49.10900  ? 20  SER E CA  1 
ATOM   5158 C  C   . SER E 1 40  ? -15.33573 -10.09109 48.79686  1.000 47.63666  ? 20  SER E C   1 
ATOM   5159 O  O   . SER E 1 40  ? -16.51279 -10.42169 48.62579  1.000 46.64594  ? 20  SER E O   1 
ATOM   5160 C  CB  . SER E 1 40  ? -14.43031 -11.21813 50.83040  1.000 47.91882  ? 20  SER E CB  1 
ATOM   5161 O  OG  . SER E 1 40  ? -13.45675 -11.89625 50.05613  1.000 49.08862  ? 20  SER E OG  1 
ATOM   5162 N  N   . ARG E 1 41  ? -14.47474 -9.91199  47.79267  1.000 44.40281  ? 21  ARG E N   1 
ATOM   5163 C  CA  . ARG E 1 41  ? -14.81748 -10.16052 46.39767  1.000 50.55285  ? 21  ARG E CA  1 
ATOM   5164 C  C   . ARG E 1 41  ? -13.97253 -11.27237 45.78686  1.000 54.75158  ? 21  ARG E C   1 
ATOM   5165 O  O   . ARG E 1 41  ? -14.04271 -11.49445 44.57228  1.000 53.27726  ? 21  ARG E O   1 
ATOM   5166 C  CB  . ARG E 1 41  ? -14.65500 -8.88075  45.57070  1.000 53.37468  ? 21  ARG E CB  1 
ATOM   5167 C  CG  . ARG E 1 41  ? -14.99721 -7.59985  46.30995  1.000 58.13000  ? 21  ARG E CG  1 
ATOM   5168 C  CD  . ARG E 1 41  ? -14.54277 -6.38282  45.51939  1.000 66.62520  ? 21  ARG E CD  1 
ATOM   5169 N  NE  . ARG E 1 41  ? -13.84554 -5.41308  46.35650  1.000 74.15250  ? 21  ARG E NE  1 
ATOM   5170 C  CZ  . ARG E 1 41  ? -13.21602 -4.34141  45.89398  1.000 83.74713  ? 21  ARG E CZ  1 
ATOM   5171 N  NH1 . ARG E 1 41  ? -13.17389 -4.06942  44.59971  1.000 83.17005  ? 21  ARG E NH1 1 
ATOM   5172 N  NH2 . ARG E 1 41  ? -12.61140 -3.52344  46.75094  1.000 84.76439  ? 21  ARG E NH2 1 
ATOM   5173 N  N   . ASP E 1 42  ? -13.17868 -11.97505 46.59272  1.000 48.28923  ? 22  ASP E N   1 
ATOM   5174 C  CA  . ASP E 1 42  ? -12.20929 -12.95521 46.11088  1.000 41.92791  ? 22  ASP E CA  1 
ATOM   5175 C  C   . ASP E 1 42  ? -12.61694 -14.33158 46.62170  1.000 42.02525  ? 22  ASP E C   1 
ATOM   5176 O  O   . ASP E 1 42  ? -12.49350 -14.61705 47.81774  1.000 49.93521  ? 22  ASP E O   1 
ATOM   5177 C  CB  . ASP E 1 42  ? -10.79919 -12.58638 46.57478  1.000 45.29515  ? 22  ASP E CB  1 
ATOM   5178 C  CG  . ASP E 1 42  ? -9.71523  -13.31146 45.80349  1.000 40.37477  ? 22  ASP E CG  1 
ATOM   5179 O  OD1 . ASP E 1 42  ? -9.97436  -14.42054 45.29423  1.000 54.89785  ? 22  ASP E OD1 1 
ATOM   5180 O  OD2 . ASP E 1 42  ? -8.59526  -12.76852 45.71050  1.000 56.22928  ? 22  ASP E OD2 1 
ATOM   5181 N  N   . THR E 1 43  ? -13.08829 -15.18653 45.71249  1.000 43.52717  ? 23  THR E N   1 
ATOM   5182 C  CA  . THR E 1 43  ? -13.52819 -16.52308 46.10180  1.000 35.01092  ? 23  THR E CA  1 
ATOM   5183 C  C   . THR E 1 43  ? -12.35553 -17.38435 46.56104  1.000 43.73597  ? 23  THR E C   1 
ATOM   5184 O  O   . THR E 1 43  ? -12.43498 -18.06009 47.59515  1.000 42.55936  ? 23  THR E O   1 
ATOM   5185 C  CB  . THR E 1 43  ? -14.26313 -17.18677 44.93504  1.000 31.92158  ? 23  THR E CB  1 
ATOM   5186 O  OG1 . THR E 1 43  ? -15.53755 -16.55454 44.75148  1.000 37.29371  ? 23  THR E OG1 1 
ATOM   5187 C  CG2 . THR E 1 43  ? -14.47468 -18.67630 45.20132  1.000 37.34567  ? 23  THR E CG2 1 
ATOM   5188 N  N   . GLY E 1 44  ? -11.25809 -17.37542 45.80172  1.000 37.11254  ? 24  GLY E N   1 
ATOM   5189 C  CA  . GLY E 1 44  ? -10.11865 -18.20565 46.15738  1.000 35.73820  ? 24  GLY E CA  1 
ATOM   5190 C  C   . GLY E 1 44  ? -9.49475  -17.81533 47.48282  1.000 33.85385  ? 24  GLY E C   1 
ATOM   5191 O  O   . GLY E 1 44  ? -9.10938  -18.67851 48.27407  1.000 36.55052  ? 24  GLY E O   1 
ATOM   5192 N  N   . GLU E 1 45  ? -9.39126  -16.51103 47.74361  1.000 34.54422  ? 25  GLU E N   1 
ATOM   5193 C  CA  . GLU E 1 45  ? -8.84906  -16.04004 49.01408  1.000 40.86728  ? 25  GLU E CA  1 
ATOM   5194 C  C   . GLU E 1 45  ? -9.68876  -16.54023 50.18421  1.000 36.30773  ? 25  GLU E C   1 
ATOM   5195 O  O   . GLU E 1 45  ? -9.15726  -17.08910 51.15990  1.000 35.12385  ? 25  GLU E O   1 
ATOM   5196 C  CB  . GLU E 1 45  ? -8.78171  -14.51323 48.99254  1.000 42.02284  ? 25  GLU E CB  1 
ATOM   5197 C  CG  . GLU E 1 45  ? -7.91861  -13.87157 50.05515  1.000 46.29881  ? 25  GLU E CG  1 
ATOM   5198 C  CD  . GLU E 1 45  ? -7.67563  -12.40010 49.76893  1.000 55.58577  ? 25  GLU E CD  1 
ATOM   5199 O  OE1 . GLU E 1 45  ? -8.40488  -11.82715 48.93260  1.000 46.25146  ? 25  GLU E OE1 1 
ATOM   5200 O  OE2 . GLU E 1 45  ? -6.74885  -11.81754 50.36595  1.000 58.34265  ? 25  GLU E OE2 1 
ATOM   5201 N  N   . VAL E 1 46  ? -11.01076 -16.37703 50.08419  1.000 36.83921  ? 26  VAL E N   1 
ATOM   5202 C  CA  . VAL E 1 46  ? -11.92441 -16.82674 51.13141  1.000 36.17510  ? 26  VAL E CA  1 
ATOM   5203 C  C   . VAL E 1 46  ? -11.81086 -18.33430 51.33477  1.000 34.92169  ? 26  VAL E C   1 
ATOM   5204 O  O   . VAL E 1 46  ? -11.74702 -18.82294 52.47057  1.000 30.42558  ? 26  VAL E O   1 
ATOM   5205 C  CB  . VAL E 1 46  ? -13.36635 -16.41126 50.78405  1.000 32.97994  ? 26  VAL E CB  1 
ATOM   5206 C  CG1 . VAL E 1 46  ? -14.36355 -17.16509 51.64991  1.000 28.15183  ? 26  VAL E CG1 1 
ATOM   5207 C  CG2 . VAL E 1 46  ? -13.53864 -14.91449 50.94638  1.000 26.66924  ? 26  VAL E CG2 1 
ATOM   5208 N  N   . HIS E 1 47  ? -11.79773 -19.09534 50.23555  1.000 30.83659  ? 27  HIS E N   1 
ATOM   5209 C  CA  . HIS E 1 47  ? -11.78019 -20.55121 50.34737  1.000 34.31241  ? 27  HIS E CA  1 
ATOM   5210 C  C   . HIS E 1 47  ? -10.47760 -21.04121 50.96558  1.000 32.09381  ? 27  HIS E C   1 
ATOM   5211 O  O   . HIS E 1 47  ? -10.48648 -21.95320 51.80269  1.000 31.25658  ? 27  HIS E O   1 
ATOM   5212 C  CB  . HIS E 1 47  ? -11.99720 -21.18745 48.97404  1.000 34.42065  ? 27  HIS E CB  1 
ATOM   5213 C  CG  . HIS E 1 47  ? -12.48348 -22.60221 49.03177  1.000 29.89568  ? 27  HIS E CG  1 
ATOM   5214 N  ND1 . HIS E 1 47  ? -13.81319 -22.92498 49.19889  1.000 29.91539  ? 27  HIS E ND1 1 
ATOM   5215 C  CD2 . HIS E 1 47  ? -11.81841 -23.77881 48.94906  1.000 34.98933  ? 27  HIS E CD2 1 
ATOM   5216 C  CE1 . HIS E 1 47  ? -13.94699 -24.23893 49.21458  1.000 26.51846  ? 27  HIS E CE1 1 
ATOM   5217 N  NE2 . HIS E 1 47  ? -12.75140 -24.78071 49.06569  1.000 33.62986  ? 27  HIS E NE2 1 
ATOM   5218 N  N   . ALA E 1 48  ? -9.34874  -20.44457 50.56842  1.000 30.67463  ? 28  ALA E N   1 
ATOM   5219 C  CA  . ALA E 1 48  ? -8.06421  -20.81721 51.14956  1.000 33.53226  ? 28  ALA E CA  1 
ATOM   5220 C  C   . ALA E 1 48  ? -8.01769  -20.49342 52.63648  1.000 34.31637  ? 28  ALA E C   1 
ATOM   5221 O  O   . ALA E 1 48  ? -7.53927  -21.30377 53.44025  1.000 34.25450  ? 28  ALA E O   1 
ATOM   5222 C  CB  . ALA E 1 48  ? -6.93119  -20.10764 50.40945  1.000 30.34707  ? 28  ALA E CB  1 
ATOM   5223 N  N   . MET E 1 49  ? -8.49857  -19.30654 53.01941  1.000 34.75427  ? 29  MET E N   1 
ATOM   5224 C  CA  . MET E 1 49  ? -8.55997  -18.95338 54.43362  1.000 33.84699  ? 29  MET E CA  1 
ATOM   5225 C  C   . MET E 1 49  ? -9.38119  -19.97328 55.21341  1.000 35.57990  ? 29  MET E C   1 
ATOM   5226 O  O   . MET E 1 49  ? -8.95221  -20.46714 56.26665  1.000 33.37972  ? 29  MET E O   1 
ATOM   5227 C  CB  . MET E 1 49  ? -9.15020  -17.55142 54.58691  1.000 42.76000  ? 29  MET E CB  1 
ATOM   5228 C  CG  . MET E 1 49  ? -8.21342  -16.54449 55.21767  1.000 49.90845  ? 29  MET E CG  1 
ATOM   5229 S  SD  . MET E 1 49  ? -8.11750  -16.75032 57.00148  1.000 62.85046  ? 29  MET E SD  1 
ATOM   5230 C  CE  . MET E 1 49  ? -9.80161  -16.35014 57.46287  1.000 53.69802  ? 29  MET E CE  1 
ATOM   5231 N  N   . LEU E 1 50  ? -10.56462 -20.31089 54.69345  1.000 38.13381  ? 30  LEU E N   1 
ATOM   5232 C  CA  . LEU E 1 50  ? -11.45409 -21.24060 55.38048  1.000 33.48268  ? 30  LEU E CA  1 
ATOM   5233 C  C   . LEU E 1 50  ? -10.80798 -22.60959 55.54179  1.000 35.68991  ? 30  LEU E C   1 
ATOM   5234 O  O   . LEU E 1 50  ? -10.84538 -23.20053 56.62695  1.000 41.46096  ? 30  LEU E O   1 
ATOM   5235 C  CB  . LEU E 1 50  ? -12.77224 -21.36028 54.61805  1.000 33.28726  ? 30  LEU E CB  1 
ATOM   5236 C  CG  . LEU E 1 50  ? -13.84592 -22.22041 55.28184  1.000 35.32280  ? 30  LEU E CG  1 
ATOM   5237 C  CD1 . LEU E 1 50  ? -14.18073 -21.68465 56.66616  1.000 25.20724  ? 30  LEU E CD1 1 
ATOM   5238 C  CD2 . LEU E 1 50  ? -15.08620 -22.27239 54.41292  1.000 31.33206  ? 30  LEU E CD2 1 
ATOM   5239 N  N   . CYS E 1 51  ? -10.20906 -23.13388 54.46992  1.000 33.74384  ? 31  CYS E N   1 
ATOM   5240 C  CA  . CYS E 1 51  ? -9.62875  -24.47117 54.54734  1.000 39.70690  ? 31  CYS E CA  1 
ATOM   5241 C  C   . CYS E 1 51  ? -8.40229  -24.49938 55.45523  1.000 37.86871  ? 31  CYS E C   1 
ATOM   5242 O  O   . CYS E 1 51  ? -8.20451  -25.46384 56.20548  1.000 38.26956  ? 31  CYS E O   1 
ATOM   5243 C  CB  . CYS E 1 51  ? -9.28453  -24.97691 53.14851  1.000 29.33666  ? 31  CYS E CB  1 
ATOM   5244 S  SG  . CYS E 1 51  ? -10.72131 -25.38433 52.12196  1.000 42.24724  ? 31  CYS E SG  1 
ATOM   5245 N  N   . ALA E 1 52  ? -7.57219  -23.45172 55.41571  1.000 34.20707  ? 32  ALA E N   1 
ATOM   5246 C  CA  . ALA E 1 52  ? -6.42092  -23.39974 56.31120  1.000 35.94550  ? 32  ALA E CA  1 
ATOM   5247 C  C   . ALA E 1 52  ? -6.86244  -23.36341 57.76796  1.000 39.11444  ? 32  ALA E C   1 
ATOM   5248 O  O   . ALA E 1 52  ? -6.29887  -24.07045 58.61651  1.000 47.49281  ? 32  ALA E O   1 
ATOM   5249 C  CB  . ALA E 1 52  ? -5.55066  -22.18730 55.98184  1.000 27.89671  ? 32  ALA E CB  1 
ATOM   5250 N  N   . CYS E 1 53  ? -7.87900  -22.55266 58.07705  1.000 39.03943  ? 33  CYS E N   1 
ATOM   5251 C  CA  . CYS E 1 53  ? -8.37549  -22.50059 59.44695  1.000 44.51586  ? 33  CYS E CA  1 
ATOM   5252 C  C   . CYS E 1 53  ? -8.97602  -23.83504 59.86921  1.000 40.26196  ? 33  CYS E C   1 
ATOM   5253 O  O   . CYS E 1 53  ? -8.77612  -24.27960 61.00652  1.000 40.83877  ? 33  CYS E O   1 
ATOM   5254 C  CB  . CYS E 1 53  ? -9.40528  -21.38487 59.59735  1.000 44.15213  ? 33  CYS E CB  1 
ATOM   5255 S  SG  . CYS E 1 53  ? -10.04135 -21.25601 61.28105  1.000 39.87507  ? 33  CYS E SG  1 
ATOM   5256 N  N   . ASP E 1 54  ? -9.72792  -24.48122 58.97215  1.000 33.34326  ? 34  ASP E N   1 
ATOM   5257 C  CA  . ASP E 1 54  ? -10.28432 -25.79311 59.28283  1.000 34.91208  ? 34  ASP E CA  1 
ATOM   5258 C  C   . ASP E 1 54  ? -9.18186  -26.79284 59.60172  1.000 48.17741  ? 34  ASP E C   1 
ATOM   5259 O  O   . ASP E 1 54  ? -9.29151  -27.56006 60.56414  1.000 46.32268  ? 34  ASP E O   1 
ATOM   5260 C  CB  . ASP E 1 54  ? -11.13887 -26.29954 58.11942  1.000 38.43660  ? 34  ASP E CB  1 
ATOM   5261 C  CG  . ASP E 1 54  ? -12.46818 -25.58005 58.00690  1.000 39.53712  ? 34  ASP E CG  1 
ATOM   5262 O  OD1 . ASP E 1 54  ? -12.90888 -24.97295 59.00511  1.000 41.38332  ? 34  ASP E OD1 1 
ATOM   5263 O  OD2 . ASP E 1 54  ? -13.07784 -25.63278 56.91752  1.000 35.91823  ? 34  ASP E OD2 1 
ATOM   5264 N  N   . ALA E 1 55  ? -8.10690  -26.79310 58.80920  1.000 49.88574  ? 35  ALA E N   1 
ATOM   5265 C  CA  . ALA E 1 55  ? -7.01297  -27.72978 59.04768  1.000 49.97800  ? 35  ALA E CA  1 
ATOM   5266 C  C   . ALA E 1 55  ? -6.34735  -27.46381 60.39212  1.000 43.72301  ? 35  ALA E C   1 
ATOM   5267 O  O   . ALA E 1 55  ? -6.08027  -28.39574 61.16324  1.000 47.00066  ? 35  ALA E O   1 
ATOM   5268 C  CB  . ALA E 1 55  ? -5.99139  -27.64588 57.91313  1.000 30.69143  ? 35  ALA E CB  1 
ATOM   5269 N  N   . HIS E 1 56  ? -6.07192  -26.19104 60.69284  1.000 43.22435  ? 36  HIS E N   1 
ATOM   5270 C  CA  . HIS E 1 56  ? -5.41329  -25.87279 61.95680  1.000 45.92789  ? 36  HIS E CA  1 
ATOM   5271 C  C   . HIS E 1 56  ? -6.28740  -26.25082 63.14897  1.000 48.79049  ? 36  HIS E C   1 
ATOM   5272 O  O   . HIS E 1 56  ? -5.80075  -26.83296 64.12750  1.000 51.67568  ? 36  HIS E O   1 
ATOM   5273 C  CB  . HIS E 1 56  ? -5.04593  -24.39129 62.00779  1.000 45.89675  ? 36  HIS E CB  1 
ATOM   5274 C  CG  . HIS E 1 56  ? -4.19214  -24.02904 63.18227  1.000 60.93523  ? 36  HIS E CG  1 
ATOM   5275 N  ND1 . HIS E 1 56  ? -4.71597  -23.75927 64.42833  1.000 60.25951  ? 36  HIS E ND1 1 
ATOM   5276 C  CD2 . HIS E 1 56  ? -2.84899  -23.90975 63.30497  1.000 62.45254  ? 36  HIS E CD2 1 
ATOM   5277 C  CE1 . HIS E 1 56  ? -3.73301  -23.48218 65.26622  1.000 63.00621  ? 36  HIS E CE1 1 
ATOM   5278 N  NE2 . HIS E 1 56  ? -2.59001  -23.56588 64.60956  1.000 66.28591  ? 36  HIS E NE2 1 
ATOM   5279 N  N   . GLN E 1 57  ? -7.58504  -25.94316 63.07991  1.000 54.87906  ? 37  GLN E N   1 
ATOM   5280 C  CA  . GLN E 1 57  ? -8.48452  -26.28287 64.17761  1.000 56.00124  ? 37  GLN E CA  1 
ATOM   5281 C  C   . GLN E 1 57  ? -8.63721  -27.79218 64.33058  1.000 52.75027  ? 37  GLN E C   1 
ATOM   5282 O  O   . GLN E 1 57  ? -8.70733  -28.30013 65.45606  1.000 49.83849  ? 37  GLN E O   1 
ATOM   5283 C  CB  . GLN E 1 57  ? -9.84488  -25.62349 63.96010  1.000 53.51662  ? 37  GLN E CB  1 
ATOM   5284 C  CG  . GLN E 1 57  ? -9.84241  -24.11524 64.15734  1.000 55.12582  ? 37  GLN E CG  1 
ATOM   5285 C  CD  . GLN E 1 57  ? -11.19858 -23.49770 63.88718  1.000 62.36791  ? 37  GLN E CD  1 
ATOM   5286 O  OE1 . GLN E 1 57  ? -11.90583 -23.90493 62.96380  1.000 54.22294  ? 37  GLN E OE1 1 
ATOM   5287 N  NE2 . GLN E 1 57  ? -11.57400 -22.51515 64.69825  1.000 61.22864  ? 37  GLN E NE2 1 
ATOM   5288 N  N   . ALA E 1 58  ? -8.68453  -28.52734 63.21453  1.000 47.46775  ? 38  ALA E N   1 
ATOM   5289 C  CA  . ALA E 1 58  ? -8.78529  -29.98089 63.29069  1.000 57.25570  ? 38  ALA E CA  1 
ATOM   5290 C  C   . ALA E 1 58  ? -7.53747  -30.58561 63.91738  1.000 57.35109  ? 38  ALA E C   1 
ATOM   5291 O  O   . ALA E 1 58  ? -7.62667  -31.54365 64.69579  1.000 55.15176  ? 38  ALA E O   1 
ATOM   5292 C  CB  . ALA E 1 58  ? -9.02296  -30.56585 61.89862  1.000 47.27220  ? 38  ALA E CB  1 
ATOM   5293 N  N   . ALA E 1 59  ? -6.36369  -30.04499 63.58290  1.000 51.83390  ? 39  ALA E N   1 
ATOM   5294 C  CA  . ALA E 1 59  ? -5.13621  -30.52166 64.20964  1.000 51.48688  ? 39  ALA E CA  1 
ATOM   5295 C  C   . ALA E 1 59  ? -5.11927  -30.20324 65.70051  1.000 64.58322  ? 39  ALA E C   1 
ATOM   5296 O  O   . ALA E 1 59  ? -4.71061  -31.03776 66.51714  1.000 65.28277  ? 39  ALA E O   1 
ATOM   5297 C  CB  . ALA E 1 59  ? -3.91908  -29.91540 63.51004  1.000 43.57323  ? 39  ALA E CB  1 
ATOM   5298 N  N   . ALA E 1 60  ? -5.57329  -29.00588 66.07666  1.000 59.29048  ? 40  ALA E N   1 
ATOM   5299 C  CA  . ALA E 1 60  ? -5.51808  -28.58651 67.47178  1.000 66.41083  ? 40  ALA E CA  1 
ATOM   5300 C  C   . ALA E 1 60  ? -6.59205  -29.23451 68.33774  1.000 69.25004  ? 40  ALA E C   1 
ATOM   5301 O  O   . ALA E 1 60  ? -6.44837  -29.25256 69.56450  1.000 64.11313  ? 40  ALA E O   1 
ATOM   5302 C  CB  . ALA E 1 60  ? -5.64131  -27.06586 67.56778  1.000 57.54190  ? 40  ALA E CB  1 
ATOM   5303 N  N   . SER E 1 61  ? -7.66071  -29.76053 67.73849  1.000 71.33603  ? 41  SER E N   1 
ATOM   5304 C  CA  . SER E 1 61  ? -8.77194  -30.31923 68.49927  1.000 69.01530  ? 41  SER E CA  1 
ATOM   5305 C  C   . SER E 1 61  ? -8.96459  -31.81234 68.26903  1.000 74.80533  ? 41  SER E C   1 
ATOM   5306 O  O   . SER E 1 61  ? -9.93305  -32.38679 68.78477  1.000 68.78022  ? 41  SER E O   1 
ATOM   5307 C  CB  . SER E 1 61  ? -10.06546 -29.57150 68.17130  1.000 67.03902  ? 41  SER E CB  1 
ATOM   5308 O  OG  . SER E 1 61  ? -10.19661 -29.40533 66.77147  1.000 72.19427  ? 41  SER E OG  1 
ATOM   5309 N  N   . GLY E 1 62  ? -8.08151  -32.45200 67.50478  1.000 72.25813  ? 42  GLY E N   1 
ATOM   5310 C  CA  . GLY E 1 62  ? -8.16995  -33.88282 67.28580  1.000 69.89099  ? 42  GLY E CA  1 
ATOM   5311 C  C   . GLY E 1 62  ? -9.36166  -34.33266 66.47415  1.000 65.00828  ? 42  GLY E C   1 
ATOM   5312 O  O   . GLY E 1 62  ? -9.78498  -35.48549 66.59751  1.000 67.04475  ? 42  GLY E O   1 
ATOM   5313 N  N   . THR E 1 63  ? -9.92237  -33.45442 65.65210  1.000 71.01601  ? 43  THR E N   1 
ATOM   5314 C  CA  . THR E 1 63  ? -11.05462 -33.77712 64.80001  1.000 68.05792  ? 43  THR E CA  1 
ATOM   5315 C  C   . THR E 1 63  ? -10.60599 -33.81658 63.34247  1.000 64.96224  ? 43  THR E C   1 
ATOM   5316 O  O   . THR E 1 63  ? -9.43437  -33.60597 63.01678  1.000 58.70392  ? 43  THR E O   1 
ATOM   5317 C  CB  . THR E 1 63  ? -12.18565 -32.76310 64.99312  1.000 67.78466  ? 43  THR E CB  1 
ATOM   5318 O  OG1 . THR E 1 63  ? -11.93423 -31.60194 64.19091  1.000 69.77368  ? 43  THR E OG1 1 
ATOM   5319 C  CG2 . THR E 1 63  ? -12.28204 -32.34306 66.45307  1.000 72.57922  ? 43  THR E CG2 1 
ATOM   5320 N  N   . SER E 1 64  ? -11.55815 -34.10037 62.46055  1.000 65.29188  ? 44  SER E N   1 
ATOM   5321 C  CA  . SER E 1 64  ? -11.34886 -34.02145 61.02264  1.000 64.32486  ? 44  SER E CA  1 
ATOM   5322 C  C   . SER E 1 64  ? -12.03084 -32.76451 60.49831  1.000 62.12929  ? 44  SER E C   1 
ATOM   5323 O  O   . SER E 1 64  ? -13.18235 -32.48494 60.84844  1.000 59.49693  ? 44  SER E O   1 
ATOM   5324 C  CB  . SER E 1 64  ? -11.89735 -35.26460 60.31820  1.000 67.81891  ? 44  SER E CB  1 
ATOM   5325 O  OG  . SER E 1 64  ? -13.30124 -35.36131 60.48053  1.000 62.67935  ? 44  SER E OG  1 
ATOM   5326 N  N   . ALA E 1 65  ? -11.32061 -32.01018 59.66819  1.000 54.23605  ? 45  ALA E N   1 
ATOM   5327 C  CA  . ALA E 1 65  ? -11.86962 -30.76348 59.15778  1.000 59.62758  ? 45  ALA E CA  1 
ATOM   5328 C  C   . ALA E 1 65  ? -13.04794 -31.04822 58.22780  1.000 53.42769  ? 45  ALA E C   1 
ATOM   5329 O  O   . ALA E 1 65  ? -13.04031 -32.04765 57.50222  1.000 56.86980  ? 45  ALA E O   1 
ATOM   5330 C  CB  . ALA E 1 65  ? -10.79551 -29.96430 58.41973  1.000 47.39981  ? 45  ALA E CB  1 
ATOM   5331 N  N   . PRO E 1 66  ? -14.07373 -30.19987 58.23135  1.000 52.58126  ? 46  PRO E N   1 
ATOM   5332 C  CA  . PRO E 1 66  ? -15.24222 -30.45147 57.38127  1.000 50.27337  ? 46  PRO E CA  1 
ATOM   5333 C  C   . PRO E 1 66  ? -14.92445 -30.25242 55.90656  1.000 47.54026  ? 46  PRO E C   1 
ATOM   5334 O  O   . PRO E 1 66  ? -13.98902 -29.54415 55.52804  1.000 48.56267  ? 46  PRO E O   1 
ATOM   5335 C  CB  . PRO E 1 66  ? -16.26438 -29.42220 57.87189  1.000 47.82878  ? 46  PRO E CB  1 
ATOM   5336 C  CG  . PRO E 1 66  ? -15.43458 -28.31348 58.42954  1.000 47.18712  ? 46  PRO E CG  1 
ATOM   5337 C  CD  . PRO E 1 66  ? -14.22871 -28.97699 59.03987  1.000 41.37240  ? 46  PRO E CD  1 
ATOM   5338 N  N   . ALA E 1 67  ? -15.72730 -30.90216 55.06615  1.000 52.55310  ? 47  ALA E N   1 
ATOM   5339 C  CA  . ALA E 1 67  ? -15.58018 -30.77891 53.62070  1.000 49.64106  ? 47  ALA E CA  1 
ATOM   5340 C  C   . ALA E 1 67  ? -16.25083 -29.49323 53.15187  1.000 39.13195  ? 47  ALA E C   1 
ATOM   5341 O  O   . ALA E 1 67  ? -17.47575 -29.35487 53.24205  1.000 44.89024  ? 47  ALA E O   1 
ATOM   5342 C  CB  . ALA E 1 67  ? -16.17932 -31.99229 52.91213  1.000 36.64044  ? 47  ALA E CB  1 
ATOM   5343 N  N   . ARG E 1 68  ? -15.45399 -28.55878 52.64687  1.000 32.51184  ? 48  ARG E N   1 
ATOM   5344 C  CA  . ARG E 1 68  ? -15.95180 -27.26102 52.21888  1.000 32.76279  ? 48  ARG E CA  1 
ATOM   5345 C  C   . ARG E 1 68  ? -16.26834 -27.28108 50.72938  1.000 43.23307  ? 48  ARG E C   1 
ATOM   5346 O  O   . ARG E 1 68  ? -15.52318 -27.85496 49.92857  1.000 41.94193  ? 48  ARG E O   1 
ATOM   5347 C  CB  . ARG E 1 68  ? -14.93624 -26.16318 52.53422  1.000 29.39491  ? 48  ARG E CB  1 
ATOM   5348 C  CG  . ARG E 1 68  ? -14.61885 -26.03638 54.01908  1.000 41.64592  ? 48  ARG E CG  1 
ATOM   5349 C  CD  . ARG E 1 68  ? -15.87438 -25.74797 54.83953  1.000 37.46940  ? 48  ARG E CD  1 
ATOM   5350 N  NE  . ARG E 1 68  ? -15.55139 -25.43053 56.22642  1.000 45.96435  ? 48  ARG E NE  1 
ATOM   5351 C  CZ  . ARG E 1 68  ? -16.41997 -24.96965 57.11696  1.000 35.33344  ? 48  ARG E CZ  1 
ATOM   5352 N  NH1 . ARG E 1 68  ? -17.68792 -24.75670 56.80228  1.000 31.01461  ? 48  ARG E NH1 1 
ATOM   5353 N  NH2 . ARG E 1 68  ? -16.00501 -24.71261 58.35391  1.000 37.59802  ? 48  ARG E NH2 1 
ATOM   5354 N  N   . ARG E 1 69  ? -17.37772 -26.64553 50.36795  1.000 38.34958  ? 49  ARG E N   1 
ATOM   5355 C  CA  . ARG E 1 69  ? -17.91197 -26.68630 49.01515  1.000 28.37622  ? 49  ARG E CA  1 
ATOM   5356 C  C   . ARG E 1 69  ? -17.56137 -25.39374 48.28843  1.000 36.51158  ? 49  ARG E C   1 
ATOM   5357 O  O   . ARG E 1 69  ? -17.85276 -24.29850 48.78181  1.000 38.67386  ? 49  ARG E O   1 
ATOM   5358 C  CB  . ARG E 1 69  ? -19.42649 -26.89785 49.05952  1.000 35.39517  ? 49  ARG E CB  1 
ATOM   5359 C  CG  . ARG E 1 69  ? -20.07757 -27.26825 47.74406  1.000 43.02410  ? 49  ARG E CG  1 
ATOM   5360 C  CD  . ARG E 1 69  ? -21.48866 -27.78674 47.99636  1.000 43.30845  ? 49  ARG E CD  1 
ATOM   5361 N  NE  . ARG E 1 69  ? -22.34023 -27.66480 46.82107  1.000 37.35074  ? 49  ARG E NE  1 
ATOM   5362 C  CZ  . ARG E 1 69  ? -22.98862 -26.55858 46.48535  1.000 39.04342  ? 49  ARG E CZ  1 
ATOM   5363 N  NH1 . ARG E 1 69  ? -22.90722 -25.46053 47.21913  1.000 36.10434  ? 49  ARG E NH1 1 
ATOM   5364 N  NH2 . ARG E 1 69  ? -23.73606 -26.55293 45.38588  1.000 38.02061  ? 49  ARG E NH2 1 
ATOM   5365 N  N   . MET E 1 70  ? -16.93289 -25.52896 47.11702  1.000 38.91221  ? 50  MET E N   1 
ATOM   5366 C  CA  . MET E 1 70  ? -16.48954 -24.35860 46.36298  1.000 40.78458  ? 50  MET E CA  1 
ATOM   5367 C  C   . MET E 1 70  ? -17.66904 -23.50511 45.90880  1.000 38.60299  ? 50  MET E C   1 
ATOM   5368 O  O   . MET E 1 70  ? -17.60023 -22.26831 45.93843  1.000 39.01004  ? 50  MET E O   1 
ATOM   5369 C  CB  . MET E 1 70  ? -15.65301 -24.80293 45.16100  1.000 45.48662  ? 50  MET E CB  1 
ATOM   5370 C  CG  . MET E 1 70  ? -14.16852 -24.50802 45.28371  1.000 52.84759  ? 50  MET E CG  1 
ATOM   5371 S  SD  . MET E 1 70  ? -13.82629 -22.73684 45.28141  1.000 75.08801  ? 50  MET E SD  1 
ATOM   5372 C  CE  . MET E 1 70  ? -14.44522 -22.27885 43.66376  1.000 63.41724  ? 50  MET E CE  1 
ATOM   5373 N  N   . GLU E 1 71  ? -18.75794 -24.14900 45.47830  1.000 37.53420  ? 51  GLU E N   1 
ATOM   5374 C  CA  . GLU E 1 71  ? -19.92625 -23.40793 45.01414  1.000 42.13366  ? 51  GLU E CA  1 
ATOM   5375 C  C   . GLU E 1 71  ? -20.52735 -22.57138 46.13723  1.000 33.32972  ? 51  GLU E C   1 
ATOM   5376 O  O   . GLU E 1 71  ? -21.00833 -21.45811 45.90098  1.000 34.08355  ? 51  GLU E O   1 
ATOM   5377 C  CB  . GLU E 1 71  ? -20.96860 -24.37242 44.44029  1.000 45.14103  ? 51  GLU E CB  1 
ATOM   5378 C  CG  . GLU E 1 71  ? -20.50828 -25.17721 43.21980  1.000 40.90238  ? 51  GLU E CG  1 
ATOM   5379 C  CD  . GLU E 1 71  ? -19.68845 -26.41003 43.58213  1.000 48.66425  ? 51  GLU E CD  1 
ATOM   5380 O  OE1 . GLU E 1 71  ? -19.01766 -26.40445 44.63643  1.000 45.34401  ? 51  GLU E OE1 1 
ATOM   5381 O  OE2 . GLU E 1 71  ? -19.71766 -27.39181 42.80998  1.000 49.21342  ? 51  GLU E OE2 1 
ATOM   5382 N  N   . THR E 1 72  ? -20.50362 -23.08970 47.36872  1.000 35.66503  ? 52  THR E N   1 
ATOM   5383 C  CA  . THR E 1 72  ? -20.95102 -22.30254 48.51297  1.000 33.76320  ? 52  THR E CA  1 
ATOM   5384 C  C   . THR E 1 72  ? -20.08394 -21.06389 48.69777  1.000 40.31490  ? 52  THR E C   1 
ATOM   5385 O  O   . THR E 1 72  ? -20.59926 -19.97259 48.96575  1.000 43.48687  ? 52  THR E O   1 
ATOM   5386 C  CB  . THR E 1 72  ? -20.94301 -23.16171 49.78015  1.000 38.60384  ? 52  THR E CB  1 
ATOM   5387 O  OG1 . THR E 1 72  ? -21.79096 -24.30048 49.59548  1.000 33.79373  ? 52  THR E OG1 1 
ATOM   5388 C  CG2 . THR E 1 72  ? -21.43579 -22.36028 50.97989  1.000 38.82775  ? 52  THR E CG2 1 
ATOM   5389 N  N   . THR E 1 73  ? -18.76440 -21.21305 48.55528  1.000 39.88722  ? 53  THR E N   1 
ATOM   5390 C  CA  . THR E 1 73  ? -17.86978 -20.06457 48.67254  1.000 39.67182  ? 53  THR E CA  1 
ATOM   5391 C  C   . THR E 1 73  ? -18.18521 -19.01795 47.61223  1.000 40.69860  ? 53  THR E C   1 
ATOM   5392 O  O   . THR E 1 73  ? -18.26572 -17.81718 47.90689  1.000 38.38942  ? 53  THR E O   1 
ATOM   5393 C  CB  . THR E 1 73  ? -16.41203 -20.51528 48.55879  1.000 34.38228  ? 53  THR E CB  1 
ATOM   5394 O  OG1 . THR E 1 73  ? -16.12238 -21.46968 49.58805  1.000 36.71660  ? 53  THR E OG1 1 
ATOM   5395 C  CG2 . THR E 1 73  ? -15.47167 -19.32208 48.69558  1.000 29.66166  ? 53  THR E CG2 1 
ATOM   5396 N  N   . GLU E 1 74  ? -18.36579 -19.45972 46.36512  1.000 39.82805  ? 54  GLU E N   1 
ATOM   5397 C  CA  . GLU E 1 74  ? -18.67383 -18.51916 45.29355  1.000 44.85206  ? 54  GLU E CA  1 
ATOM   5398 C  C   . GLU E 1 74  ? -20.00591 -17.82383 45.54565  1.000 41.30411  ? 54  GLU E C   1 
ATOM   5399 O  O   . GLU E 1 74  ? -20.13308 -16.61417 45.32692  1.000 50.26054  ? 54  GLU E O   1 
ATOM   5400 C  CB  . GLU E 1 74  ? -18.68124 -19.24182 43.94527  1.000 45.26085  ? 54  GLU E CB  1 
ATOM   5401 C  CG  . GLU E 1 74  ? -18.02458 -18.45706 42.81989  1.000 54.15112  ? 54  GLU E CG  1 
ATOM   5402 C  CD  . GLU E 1 74  ? -18.78263 -17.19399 42.46669  1.000 66.02741  ? 54  GLU E CD  1 
ATOM   5403 O  OE1 . GLU E 1 74  ? -20.01342 -17.27337 42.27132  1.000 67.68789  ? 54  GLU E OE1 1 
ATOM   5404 O  OE2 . GLU E 1 74  ? -18.15034 -16.11832 42.39066  1.000 68.94243  ? 54  GLU E OE2 1 
ATOM   5405 N  N   . HIS E 1 75  ? -21.00352 -18.56988 46.02689  1.000 34.97269  ? 55  HIS E N   1 
ATOM   5406 C  CA  . HIS E 1 75  ? -22.30820 -17.98561 46.32077  1.000 36.48898  ? 55  HIS E CA  1 
ATOM   5407 C  C   . HIS E 1 75  ? -22.21095 -16.94682 47.43164  1.000 43.66277  ? 55  HIS E C   1 
ATOM   5408 O  O   . HIS E 1 75  ? -22.78033 -15.85510 47.32446  1.000 40.60597  ? 55  HIS E O   1 
ATOM   5409 C  CB  . HIS E 1 75  ? -23.29431 -19.09348 46.69780  1.000 43.50481  ? 55  HIS E CB  1 
ATOM   5410 C  CG  . HIS E 1 75  ? -24.66032 -18.59969 47.06623  1.000 45.67565  ? 55  HIS E CG  1 
ATOM   5411 N  ND1 . HIS E 1 75  ? -25.49654 -19.29575 47.91444  1.000 46.82372  ? 55  HIS E ND1 1 
ATOM   5412 C  CD2 . HIS E 1 75  ? -25.33834 -17.48557 46.70055  1.000 42.90031  ? 55  HIS E CD2 1 
ATOM   5413 C  CE1 . HIS E 1 75  ? -26.62915 -18.63101 48.05734  1.000 38.32921  ? 55  HIS E CE1 1 
ATOM   5414 N  NE2 . HIS E 1 75  ? -26.55864 -17.52893 47.33169  1.000 45.19721  ? 55  HIS E NE2 1 
ATOM   5415 N  N   . ARG E 1 76  ? -21.49054 -17.26949 48.51018  1.000 40.68514  ? 56  ARG E N   1 
ATOM   5416 C  CA  . ARG E 1 76  ? -21.37002 -16.33324 49.62312  1.000 37.23478  ? 56  ARG E CA  1 
ATOM   5417 C  C   . ARG E 1 76  ? -20.61948 -15.07479 49.20880  1.000 37.78358  ? 56  ARG E C   1 
ATOM   5418 O  O   . ARG E 1 76  ? -21.00780 -13.96371 49.58841  1.000 42.53200  ? 56  ARG E O   1 
ATOM   5419 C  CB  . ARG E 1 76  ? -20.67413 -16.99862 50.81171  1.000 39.40121  ? 56  ARG E CB  1 
ATOM   5420 C  CG  . ARG E 1 76  ? -21.37157 -18.22946 51.35517  1.000 35.91378  ? 56  ARG E CG  1 
ATOM   5421 C  CD  . ARG E 1 76  ? -22.85426 -18.00539 51.56111  1.000 33.02201  ? 56  ARG E CD  1 
ATOM   5422 N  NE  . ARG E 1 76  ? -23.51298 -19.23888 51.97375  1.000 47.25150  ? 56  ARG E NE  1 
ATOM   5423 C  CZ  . ARG E 1 76  ? -24.82630 -19.41296 52.01033  1.000 44.91714  ? 56  ARG E CZ  1 
ATOM   5424 N  NH1 . ARG E 1 76  ? -25.66152 -18.44565 51.66791  1.000 44.87398  ? 56  ARG E NH1 1 
ATOM   5425 N  NH2 . ARG E 1 76  ? -25.31349 -20.58833 52.39658  1.000 42.02289  ? 56  ARG E NH2 1 
ATOM   5426 N  N   . VAL E 1 77  ? -19.54435 -15.22407 48.43166  1.000 45.24840  ? 57  VAL E N   1 
ATOM   5427 C  CA  . VAL E 1 77  ? -18.76827 -14.05907 48.01704  1.000 42.11080  ? 57  VAL E CA  1 
ATOM   5428 C  C   . VAL E 1 77  ? -19.58182 -13.18641 47.06806  1.000 47.61742  ? 57  VAL E C   1 
ATOM   5429 O  O   . VAL E 1 77  ? -19.64405 -11.96089 47.22742  1.000 45.93908  ? 57  VAL E O   1 
ATOM   5430 C  CB  . VAL E 1 77  ? -17.43630 -14.49863 47.38371  1.000 40.30207  ? 57  VAL E CB  1 
ATOM   5431 C  CG1 . VAL E 1 77  ? -16.72231 -13.30506 46.76988  1.000 41.88600  ? 57  VAL E CG1 1 
ATOM   5432 C  CG2 . VAL E 1 77  ? -16.55280 -15.16435 48.42443  1.000 38.49786  ? 57  VAL E CG2 1 
ATOM   5433 N  N   . ARG E 1 78  ? -20.23113 -13.80454 46.07480  1.000 44.44197  ? 58  ARG E N   1 
ATOM   5434 C  CA  . ARG E 1 78  ? -21.00857 -13.03755 45.10838  1.000 47.84792  ? 58  ARG E CA  1 
ATOM   5435 C  C   . ARG E 1 78  ? -22.25838 -12.42576 45.72650  1.000 53.98299  ? 58  ARG E C   1 
ATOM   5436 O  O   . ARG E 1 78  ? -22.83565 -11.50336 45.14149  1.000 57.00971  ? 58  ARG E O   1 
ATOM   5437 C  CB  . ARG E 1 78  ? -21.38429 -13.91715 43.91048  1.000 49.02260  ? 58  ARG E CB  1 
ATOM   5438 C  CG  . ARG E 1 78  ? -22.50831 -14.92785 44.15030  1.000 57.81888  ? 58  ARG E CG  1 
ATOM   5439 C  CD  . ARG E 1 78  ? -22.71345 -15.77679 42.89236  1.000 59.41190  ? 58  ARG E CD  1 
ATOM   5440 N  NE  . ARG E 1 78  ? -23.92393 -16.59191 42.91680  1.000 62.06743  ? 58  ARG E NE  1 
ATOM   5441 C  CZ  . ARG E 1 78  ? -23.94298 -17.91894 42.88551  1.000 64.38168  ? 58  ARG E CZ  1 
ATOM   5442 N  NH1 . ARG E 1 78  ? -22.82550 -18.62808 42.87492  1.000 57.02639  ? 58  ARG E NH1 1 
ATOM   5443 N  NH2 . ARG E 1 78  ? -25.11359 -18.55056 42.84542  1.000 51.59328  ? 58  ARG E NH2 1 
ATOM   5444 N  N   . SER E 1 79  ? -22.68592 -12.91198 46.88801  1.000 49.50014  ? 59  SER E N   1 
ATOM   5445 C  CA  . SER E 1 79  ? -23.79484 -12.31669 47.61811  1.000 44.39093  ? 59  SER E CA  1 
ATOM   5446 C  C   . SER E 1 79  ? -23.35469 -11.19232 48.54549  1.000 49.17433  ? 59  SER E C   1 
ATOM   5447 O  O   . SER E 1 79  ? -24.20635 -10.57556 49.19260  1.000 54.54431  ? 59  SER E O   1 
ATOM   5448 C  CB  . SER E 1 79  ? -24.52732 -13.38912 48.43087  1.000 46.46773  ? 59  SER E CB  1 
ATOM   5449 O  OG  . SER E 1 79  ? -24.98451 -14.43740 47.59384  1.000 51.76604  ? 59  SER E OG  1 
ATOM   5450 N  N   . GLY E 1 80  ? -22.05697 -10.90971 48.62694  1.000 47.21267  ? 60  GLY E N   1 
ATOM   5451 C  CA  . GLY E 1 80  ? -21.57594 -9.91133  49.56275  1.000 41.13834  ? 60  GLY E CA  1 
ATOM   5452 C  C   . GLY E 1 80  ? -21.73894 -10.30118 51.01365  1.000 43.47065  ? 60  GLY E C   1 
ATOM   5453 O  O   . GLY E 1 80  ? -21.77645 -9.42535  51.88413  1.000 48.85336  ? 60  GLY E O   1 
ATOM   5454 N  N   . SER E 1 81  ? -21.83491 -11.59894 51.29965  1.000 44.44489  ? 61  SER E N   1 
ATOM   5455 C  CA  . SER E 1 81  ? -22.08667 -12.08206 52.64988  1.000 42.04801  ? 61  SER E CA  1 
ATOM   5456 C  C   . SER E 1 81  ? -20.81626 -12.33879 53.44874  1.000 44.61255  ? 61  SER E C   1 
ATOM   5457 O  O   . SER E 1 81  ? -20.90295 -12.55513 54.66178  1.000 38.98775  ? 61  SER E O   1 
ATOM   5458 C  CB  . SER E 1 81  ? -22.91143 -13.37450 52.59944  1.000 39.64582  ? 61  SER E CB  1 
ATOM   5459 O  OG  . SER E 1 81  ? -24.11357 -13.18829 51.87425  1.000 50.58792  ? 61  SER E OG  1 
ATOM   5460 N  N   . VAL E 1 82  ? -19.65059 -12.32561 52.81023  1.000 43.14627  ? 62  VAL E N   1 
ATOM   5461 C  CA  . VAL E 1 82  ? -18.38935 -12.65282 53.46491  1.000 40.05246  ? 62  VAL E CA  1 
ATOM   5462 C  C   . VAL E 1 82  ? -17.69009 -11.35707 53.84463  1.000 39.16896  ? 62  VAL E C   1 
ATOM   5463 O  O   . VAL E 1 82  ? -17.32635 -10.55807 52.97328  1.000 43.41801  ? 62  VAL E O   1 
ATOM   5464 C  CB  . VAL E 1 82  ? -17.49232 -13.51484 52.56327  1.000 38.92846  ? 62  VAL E CB  1 
ATOM   5465 C  CG1 . VAL E 1 82  ? -16.24947 -13.95341 53.32251  1.000 36.69503  ? 62  VAL E CG1 1 
ATOM   5466 C  CG2 . VAL E 1 82  ? -18.25961 -14.71512 52.04697  1.000 27.24224  ? 62  VAL E CG2 1 
ATOM   5467 N  N   . HIS E 1 83  ? -17.49898 -11.15073 55.14298  1.000 40.51774  ? 63  HIS E N   1 
ATOM   5468 C  CA  . HIS E 1 83  ? -16.76707 -10.00330 55.65878  1.000 35.17693  ? 63  HIS E CA  1 
ATOM   5469 C  C   . HIS E 1 83  ? -15.39932 -10.48367 56.12394  1.000 33.69782  ? 63  HIS E C   1 
ATOM   5470 O  O   . HIS E 1 83  ? -15.30772 -11.38242 56.96937  1.000 38.50128  ? 63  HIS E O   1 
ATOM   5471 C  CB  . HIS E 1 83  ? -17.53429 -9.33720  56.79874  1.000 36.99913  ? 63  HIS E CB  1 
ATOM   5472 C  CG  . HIS E 1 83  ? -18.93398 -8.94874  56.43487  1.000 39.43070  ? 63  HIS E CG  1 
ATOM   5473 N  ND1 . HIS E 1 83  ? -19.32165 -7.63707  56.25809  1.000 38.64882  ? 63  HIS E ND1 1 
ATOM   5474 C  CD2 . HIS E 1 83  ? -20.03762 -9.70106  56.21079  1.000 35.57582  ? 63  HIS E CD2 1 
ATOM   5475 C  CE1 . HIS E 1 83  ? -20.60403 -7.59823  55.94310  1.000 44.60509  ? 63  HIS E CE1 1 
ATOM   5476 N  NE2 . HIS E 1 83  ? -21.06177 -8.83713  55.90693  1.000 51.95779  ? 63  HIS E NE2 1 
ATOM   5477 N  N   . LEU E 1 84  ? -14.34523 -9.88723  55.57137  1.000 38.75302  ? 64  LEU E N   1 
ATOM   5478 C  CA  . LEU E 1 84  ? -12.97890 -10.34923 55.76901  1.000 34.65625  ? 64  LEU E CA  1 
ATOM   5479 C  C   . LEU E 1 84  ? -12.16346 -9.27022  56.46681  1.000 38.81127  ? 64  LEU E C   1 
ATOM   5480 O  O   . LEU E 1 84  ? -12.17523 -8.10554  56.05069  1.000 45.79876  ? 64  LEU E O   1 
ATOM   5481 C  CB  . LEU E 1 84  ? -12.33912 -10.72657 54.42760  1.000 42.77839  ? 64  LEU E CB  1 
ATOM   5482 C  CG  . LEU E 1 84  ? -10.98762 -11.44212 54.44615  1.000 44.96115  ? 64  LEU E CG  1 
ATOM   5483 C  CD1 . LEU E 1 84  ? -10.99891 -12.58557 53.44600  1.000 40.73989  ? 64  LEU E CD1 1 
ATOM   5484 C  CD2 . LEU E 1 84  ? -9.85250  -10.47694 54.13573  1.000 41.02830  ? 64  LEU E CD2 1 
ATOM   5485 N  N   . LEU E 1 85  ? -11.46813 -9.66350  57.52977  1.000 42.66185  ? 65  LEU E N   1 
ATOM   5486 C  CA  . LEU E 1 85  ? -10.56191 -8.79832  58.26882  1.000 47.76227  ? 65  LEU E CA  1 
ATOM   5487 C  C   . LEU E 1 85  ? -9.14223  -9.06587  57.78936  1.000 48.77057  ? 65  LEU E C   1 
ATOM   5488 O  O   . LEU E 1 85  ? -8.63335  -10.18625 57.93299  1.000 46.56306  ? 65  LEU E O   1 
ATOM   5489 C  CB  . LEU E 1 85  ? -10.67773 -9.04422  59.77288  1.000 45.66042  ? 65  LEU E CB  1 
ATOM   5490 C  CG  . LEU E 1 85  ? -9.59177  -8.42407  60.65538  1.000 45.26986  ? 65  LEU E CG  1 
ATOM   5491 C  CD1 . LEU E 1 85  ? -9.61135  -6.90329  60.57202  1.000 51.28490  ? 65  LEU E CD1 1 
ATOM   5492 C  CD2 . LEU E 1 85  ? -9.73945  -8.89355  62.09687  1.000 41.50767  ? 65  LEU E CD2 1 
ATOM   5493 N  N   . ARG E 1 86  ? -8.51190  -8.03027  57.24371  1.000 53.08710  ? 66  ARG E N   1 
ATOM   5494 C  CA  . ARG E 1 86  ? -7.19653  -8.08476  56.63192  1.000 55.30185  ? 66  ARG E CA  1 
ATOM   5495 C  C   . ARG E 1 86  ? -6.21193  -7.32205  57.50818  1.000 60.54079  ? 66  ARG E C   1 
ATOM   5496 O  O   . ARG E 1 86  ? -6.56517  -6.30055  58.10929  1.000 65.24258  ? 66  ARG E O   1 
ATOM   5497 C  CB  . ARG E 1 86  ? -7.25526  -7.47030  55.22901  1.000 54.09553  ? 66  ARG E CB  1 
ATOM   5498 C  CG  . ARG E 1 86  ? -6.12177  -7.83291  54.30285  1.000 54.42343  ? 66  ARG E CG  1 
ATOM   5499 C  CD  . ARG E 1 86  ? -6.30612  -7.17783  52.93803  1.000 56.31788  ? 66  ARG E CD  1 
ATOM   5500 N  NE  . ARG E 1 86  ? -7.47689  -7.67984  52.22769  1.000 50.82662  ? 66  ARG E NE  1 
ATOM   5501 C  CZ  . ARG E 1 86  ? -7.47211  -8.74658  51.43919  1.000 53.33345  ? 66  ARG E CZ  1 
ATOM   5502 N  NH1 . ARG E 1 86  ? -6.37510  -9.46253  51.25162  1.000 41.83443  ? 66  ARG E NH1 1 
ATOM   5503 N  NH2 . ARG E 1 86  ? -8.59580  -9.10449  50.82369  1.000 43.93502  ? 66  ARG E NH2 1 
ATOM   5504 N  N   . HIS E 1 87  ? -4.98214  -7.82450  57.59380  1.000 59.31613  ? 67  HIS E N   1 
ATOM   5505 C  CA  . HIS E 1 87  ? -3.93239  -7.18208  58.37650  1.000 71.10096  ? 67  HIS E CA  1 
ATOM   5506 C  C   . HIS E 1 87  ? -2.66771  -7.10584  57.53538  1.000 75.20483  ? 67  HIS E C   1 
ATOM   5507 O  O   . HIS E 1 87  ? -2.10330  -8.14165  57.16801  1.000 73.03299  ? 67  HIS E O   1 
ATOM   5508 C  CB  . HIS E 1 87  ? -3.66591  -7.93794  59.68136  1.000 59.29938  ? 67  HIS E CB  1 
ATOM   5509 C  CG  . HIS E 1 87  ? -2.64238  -7.28166  60.55516  1.000 72.03687  ? 67  HIS E CG  1 
ATOM   5510 N  ND1 . HIS E 1 87  ? -2.79167  -6.00097  61.04434  1.000 69.39760  ? 67  HIS E ND1 1 
ATOM   5511 C  CD2 . HIS E 1 87  ? -1.45328  -7.72737  61.02502  1.000 70.59117  ? 67  HIS E CD2 1 
ATOM   5512 C  CE1 . HIS E 1 87  ? -1.74006  -5.68775  61.78019  1.000 66.43558  ? 67  HIS E CE1 1 
ATOM   5513 N  NE2 . HIS E 1 87  ? -0.91327  -6.71802  61.78465  1.000 71.70554  ? 67  HIS E NE2 1 
ATOM   5514 N  N   . ASP E 1 88  ? -2.22600  -5.88114  57.24086  1.000 77.52607  ? 68  ASP E N   1 
ATOM   5515 C  CA  . ASP E 1 88  ? -1.06493  -5.63533  56.38511  1.000 79.25235  ? 68  ASP E CA  1 
ATOM   5516 C  C   . ASP E 1 88  ? -1.23585  -6.29351  55.01902  1.000 70.93328  ? 68  ASP E C   1 
ATOM   5517 O  O   . ASP E 1 88  ? -0.28847  -6.83598  54.44727  1.000 73.19264  ? 68  ASP E O   1 
ATOM   5518 C  CB  . ASP E 1 88  ? 0.23382   -6.09628  57.05085  1.000 89.96932  ? 68  ASP E CB  1 
ATOM   5519 C  CG  . ASP E 1 88  ? 0.65499   -5.19713  58.19443  1.000 100.95267 ? 68  ASP E CG  1 
ATOM   5520 O  OD1 . ASP E 1 88  ? 0.24177   -4.01765  58.21406  1.000 102.19589 ? 68  ASP E OD1 1 
ATOM   5521 O  OD2 . ASP E 1 88  ? 1.40994   -5.67014  59.07166  1.000 99.93632  ? 68  ASP E OD2 1 
ATOM   5522 N  N   . GLY E 1 89  ? -2.45920  -6.25126  54.49344  1.000 62.99878  ? 69  GLY E N   1 
ATOM   5523 C  CA  . GLY E 1 89  ? -2.75650  -6.82400  53.19997  1.000 66.04468  ? 69  GLY E CA  1 
ATOM   5524 C  C   . GLY E 1 89  ? -3.03923  -8.31092  53.19449  1.000 61.40788  ? 69  GLY E C   1 
ATOM   5525 O  O   . GLY E 1 89  ? -3.55523  -8.82091  52.19155  1.000 64.49404  ? 69  GLY E O   1 
ATOM   5526 N  N   . ARG E 1 90  ? -2.73563  -9.02484  54.28142  1.000 56.67017  ? 70  ARG E N   1 
ATOM   5527 C  CA  . ARG E 1 90  ? -2.93674  -10.46429 54.37185  1.000 59.71117  ? 70  ARG E CA  1 
ATOM   5528 C  C   . ARG E 1 90  ? -4.22901  -10.78357 55.11601  1.000 65.78067  ? 70  ARG E C   1 
ATOM   5529 O  O   . ARG E 1 90  ? -4.54728  -10.12992 56.11694  1.000 62.07664  ? 70  ARG E O   1 
ATOM   5530 C  CB  . ARG E 1 90  ? -1.76232  -11.12582 55.09344  1.000 60.32110  ? 70  ARG E CB  1 
ATOM   5531 C  CG  . ARG E 1 90  ? -1.45566  -12.55426 54.65534  1.000 77.08642  ? 70  ARG E CG  1 
ATOM   5532 C  CD  . ARG E 1 90  ? -0.42706  -13.16593 55.58969  1.000 88.83619  ? 70  ARG E CD  1 
ATOM   5533 N  NE  . ARG E 1 90  ? 0.35719   -12.12893 56.25015  1.000 98.52055  ? 70  ARG E NE  1 
ATOM   5534 C  CZ  . ARG E 1 90  ? 0.95289   -12.27431 57.42558  1.000 98.76908  ? 70  ARG E CZ  1 
ATOM   5535 N  NH1 . ARG E 1 90  ? 0.88885   -13.41263 58.09640  1.000 92.74162  ? 70  ARG E NH1 1 
ATOM   5536 N  NH2 . ARG E 1 90  ? 1.61829   -11.24767 57.94738  1.000 92.07045  ? 70  ARG E NH2 1 
ATOM   5537 N  N   . PRO E 1 91  ? -4.99110  -11.77862 54.65749  1.000 61.60466  ? 71  PRO E N   1 
ATOM   5538 C  CA  . PRO E 1 91  ? -6.23966  -12.14007 55.35005  1.000 52.77236  ? 71  PRO E CA  1 
ATOM   5539 C  C   . PRO E 1 91  ? -5.95710  -12.67416 56.74609  1.000 52.07621  ? 71  PRO E C   1 
ATOM   5540 O  O   . PRO E 1 91  ? -5.21752  -13.64524 56.91844  1.000 57.96208  ? 71  PRO E O   1 
ATOM   5541 C  CB  . PRO E 1 91  ? -6.84981  -13.22055 54.44899  1.000 51.51536  ? 71  PRO E CB  1 
ATOM   5542 C  CG  . PRO E 1 91  ? -6.17127  -13.06325 53.13428  1.000 56.49122  ? 71  PRO E CG  1 
ATOM   5543 C  CD  . PRO E 1 91  ? -4.79438  -12.56682 53.42893  1.000 54.82587  ? 71  PRO E CD  1 
ATOM   5544 N  N   . ALA E 1 92  ? -6.56228  -12.03885 57.74435  1.000 51.62873  ? 72  ALA E N   1 
ATOM   5545 C  CA  . ALA E 1 92  ? -6.39875  -12.44760 59.13314  1.000 49.59472  ? 72  ALA E CA  1 
ATOM   5546 C  C   . ALA E 1 92  ? -7.59812  -13.21281 59.66982  1.000 44.41478  ? 72  ALA E C   1 
ATOM   5547 O  O   . ALA E 1 92  ? -7.42546  -14.16897 60.43209  1.000 39.96454  ? 72  ALA E O   1 
ATOM   5548 C  CB  . ALA E 1 92  ? -6.13719  -11.22732 60.02233  1.000 47.78213  ? 72  ALA E CB  1 
ATOM   5549 N  N   . GLY E 1 93  ? -8.81022  -12.80860 59.29892  1.000 42.10898  ? 73  GLY E N   1 
ATOM   5550 C  CA  . GLY E 1 93  ? -10.00483 -13.50275 59.74414  1.000 35.93639  ? 73  GLY E CA  1 
ATOM   5551 C  C   . GLY E 1 93  ? -11.14690 -13.21102 58.79800  1.000 39.14430  ? 73  GLY E C   1 
ATOM   5552 O  O   . GLY E 1 93  ? -11.00720 -12.43320 57.85392  1.000 44.12591  ? 73  GLY E O   1 
ATOM   5553 N  N   . MET E 1 94  ? -12.29268 -13.83527 59.06449  1.000 34.76270  ? 74  MET E N   1 
ATOM   5554 C  CA  . MET E 1 94  ? -13.47974 -13.58889 58.25218  1.000 36.95151  ? 74  MET E CA  1 
ATOM   5555 C  C   . MET E 1 94  ? -14.68860 -14.23705 58.91122  1.000 33.55052  ? 74  MET E C   1 
ATOM   5556 O  O   . MET E 1 94  ? -14.56475 -15.02809 59.84955  1.000 34.34955  ? 74  MET E O   1 
ATOM   5557 C  CB  . MET E 1 94  ? -13.31330 -14.11896 56.82298  1.000 35.91504  ? 74  MET E CB  1 
ATOM   5558 C  CG  . MET E 1 94  ? -13.33901 -15.63006 56.72651  1.000 31.83838  ? 74  MET E CG  1 
ATOM   5559 S  SD  . MET E 1 94  ? -13.40611 -16.19328 55.01820  1.000 33.64645  ? 74  MET E SD  1 
ATOM   5560 C  CE  . MET E 1 94  ? -13.40098 -17.96129 55.26267  1.000 25.32684  ? 74  MET E CE  1 
ATOM   5561 N  N   . PHE E 1 95  ? -15.86440 -13.88409 58.39595  1.000 32.07400  ? 75  PHE E N   1 
ATOM   5562 C  CA  . PHE E 1 95  ? -17.10470 -14.56600 58.74541  1.000 34.58562  ? 75  PHE E CA  1 
ATOM   5563 C  C   . PHE E 1 95  ? -18.08783 -14.40120 57.59467  1.000 35.41295  ? 75  PHE E C   1 
ATOM   5564 O  O   . PHE E 1 95  ? -17.89663 -13.56434 56.70724  1.000 35.57169  ? 75  PHE E O   1 
ATOM   5565 C  CB  . PHE E 1 95  ? -17.70145 -14.04255 60.06010  1.000 31.44512  ? 75  PHE E CB  1 
ATOM   5566 C  CG  . PHE E 1 95  ? -18.11494 -12.59493 60.01754  1.000 38.78468  ? 75  PHE E CG  1 
ATOM   5567 C  CD1 . PHE E 1 95  ? -19.40254 -12.23639 59.64494  1.000 34.39029  ? 75  PHE E CD1 1 
ATOM   5568 C  CD2 . PHE E 1 95  ? -17.22411 -11.59613 60.37252  1.000 36.98310  ? 75  PHE E CD2 1 
ATOM   5569 C  CE1 . PHE E 1 95  ? -19.78620 -10.90989 59.61139  1.000 38.46192  ? 75  PHE E CE1 1 
ATOM   5570 C  CE2 . PHE E 1 95  ? -17.60355 -10.26540 60.34139  1.000 39.33400  ? 75  PHE E CE2 1 
ATOM   5571 C  CZ  . PHE E 1 95  ? -18.88588 -9.92357  59.96022  1.000 38.67116  ? 75  PHE E CZ  1 
ATOM   5572 N  N   . THR E 1 96  ? -19.14282 -15.21553 57.61163  1.000 34.45270  ? 76  THR E N   1 
ATOM   5573 C  CA  . THR E 1 96  ? -20.19450 -15.16043 56.60776  1.000 43.52456  ? 76  THR E CA  1 
ATOM   5574 C  C   . THR E 1 96  ? -21.51465 -14.87188 57.30516  1.000 41.21090  ? 76  THR E C   1 
ATOM   5575 O  O   . THR E 1 96  ? -21.89398 -15.58332 58.24130  1.000 38.34287  ? 76  THR E O   1 
ATOM   5576 C  CB  . THR E 1 96  ? -20.27983 -16.47535 55.82202  1.000 40.70021  ? 76  THR E CB  1 
ATOM   5577 O  OG1 . THR E 1 96  ? -19.04144 -16.70936 55.14011  1.000 49.86768  ? 76  THR E OG1 1 
ATOM   5578 C  CG2 . THR E 1 96  ? -21.40804 -16.41755 54.80305  1.000 42.59766  ? 76  THR E CG2 1 
ATOM   5579 N  N   . LEU E 1 97  ? -22.20440 -13.82736 56.85584  1.000 40.20958  ? 77  LEU E N   1 
ATOM   5580 C  CA  . LEU E 1 97  ? -23.45222 -13.38107 57.46356  1.000 43.66209  ? 77  LEU E CA  1 
ATOM   5581 C  C   . LEU E 1 97  ? -24.53727 -13.36754 56.39767  1.000 42.47623  ? 77  LEU E C   1 
ATOM   5582 O  O   . LEU E 1 97  ? -24.44107 -12.61564 55.42203  1.000 44.42739  ? 77  LEU E O   1 
ATOM   5583 C  CB  . LEU E 1 97  ? -23.28647 -11.99338 58.08781  1.000 37.95845  ? 77  LEU E CB  1 
ATOM   5584 C  CG  . LEU E 1 97  ? -24.49210 -11.41554 58.82831  1.000 45.82640  ? 77  LEU E CG  1 
ATOM   5585 C  CD1 . LEU E 1 97  ? -24.84077 -12.26570 60.03881  1.000 48.07224  ? 77  LEU E CD1 1 
ATOM   5586 C  CD2 . LEU E 1 97  ? -24.21898 -9.97925  59.24264  1.000 48.65837  ? 77  LEU E CD2 1 
ATOM   5587 N  N   . THR E 1 98  ? -25.56714 -14.19063 56.58391  1.000 44.30612  ? 78  THR E N   1 
ATOM   5588 C  CA  . THR E 1 98  ? -26.62874 -14.31443 55.59248  1.000 49.96053  ? 78  THR E CA  1 
ATOM   5589 C  C   . THR E 1 98  ? -27.99491 -14.11192 56.23715  1.000 55.21941  ? 78  THR E C   1 
ATOM   5590 O  O   . THR E 1 98  ? -28.15998 -14.22919 57.45265  1.000 56.50330  ? 78  THR E O   1 
ATOM   5591 C  CB  . THR E 1 98  ? -26.58642 -15.67719 54.87753  1.000 47.35153  ? 78  THR E CB  1 
ATOM   5592 O  OG1 . THR E 1 98  ? -26.53681 -16.73319 55.84534  1.000 38.89712  ? 78  THR E OG1 1 
ATOM   5593 C  CG2 . THR E 1 98  ? -25.37468 -15.76903 53.96221  1.000 46.40049  ? 78  THR E CG2 1 
ATOM   5594 N  N   . TRP E 1 99  ? -28.98107 -13.78605 55.39730  1.000 57.47478  ? 79  TRP E N   1 
ATOM   5595 C  CA  . TRP E 1 99  ? -30.36345 -13.70937 55.85408  1.000 54.49949  ? 79  TRP E CA  1 
ATOM   5596 C  C   . TRP E 1 99  ? -31.05845 -15.06255 55.82419  1.000 53.29537  ? 79  TRP E C   1 
ATOM   5597 O  O   . TRP E 1 99  ? -32.00930 -15.27435 56.58397  1.000 67.82031  ? 79  TRP E O   1 
ATOM   5598 C  CB  . TRP E 1 99  ? -31.15294 -12.71019 55.00253  1.000 51.25644  ? 79  TRP E CB  1 
ATOM   5599 C  CG  . TRP E 1 99  ? -30.79589 -11.27571 55.26117  1.000 51.87546  ? 79  TRP E CG  1 
ATOM   5600 C  CD1 . TRP E 1 99  ? -29.96499 -10.48958 54.51645  1.000 56.47291  ? 79  TRP E CD1 1 
ATOM   5601 C  CD2 . TRP E 1 99  ? -31.25860 -10.45676 56.34356  1.000 54.87873  ? 79  TRP E CD2 1 
ATOM   5602 N  NE1 . TRP E 1 99  ? -29.88297 -9.23243  55.06666  1.000 53.06498  ? 79  TRP E NE1 1 
ATOM   5603 C  CE2 . TRP E 1 99  ? -30.66701 -9.18694  56.18923  1.000 51.53868  ? 79  TRP E CE2 1 
ATOM   5604 C  CE3 . TRP E 1 99  ? -32.11483 -10.67428 57.42722  1.000 47.70886  ? 79  TRP E CE3 1 
ATOM   5605 C  CZ2 . TRP E 1 99  ? -30.90484 -8.13933  57.07713  1.000 53.56851  ? 79  TRP E CZ2 1 
ATOM   5606 C  CZ3 . TRP E 1 99  ? -32.34915 -9.63346  58.30713  1.000 54.04737  ? 79  TRP E CZ3 1 
ATOM   5607 C  CH2 . TRP E 1 99  ? -31.74661 -8.38199  58.12703  1.000 58.71377  ? 79  TRP E CH2 1 
ATOM   5608 N  N   . ASP E 1 100 ? -30.60077 -15.97867 54.97185  1.000 53.17757  ? 80  ASP E N   1 
ATOM   5609 C  CA  . ASP E 1 100 ? -31.04857 -17.34517 54.76847  1.000 56.75024  ? 80  ASP E CA  1 
ATOM   5610 C  C   . ASP E 1 100 ? -30.16176 -18.32082 55.53512  1.000 59.53688  ? 80  ASP E C   1 
ATOM   5611 O  O   . ASP E 1 100 ? -28.96617 -18.07154 55.71617  1.000 62.54223  ? 80  ASP E O   1 
ATOM   5612 C  CB  . ASP E 1 100 ? -31.03064 -17.69751 53.27824  1.000 57.96993  ? 80  ASP E CB  1 
ATOM   5613 C  CG  . ASP E 1 100 ? -29.76608 -17.22590 52.58309  1.000 67.88501  ? 80  ASP E CG  1 
ATOM   5614 O  OD1 . ASP E 1 100 ? -29.33684 -16.07788 52.83162  1.000 64.48299  ? 80  ASP E OD1 1 
ATOM   5615 O  OD2 . ASP E 1 100 ? -29.19780 -18.00447 51.78853  1.000 63.84131  ? 80  ASP E OD2 1 
ATOM   5616 N  N   . PRO E 1 101 ? -30.71299 -19.43989 55.99744  1.000 56.70717  ? 81  PRO E N   1 
ATOM   5617 C  CA  . PRO E 1 101 ? -29.91697 -20.39190 56.78027  1.000 60.00873  ? 81  PRO E CA  1 
ATOM   5618 C  C   . PRO E 1 101 ? -28.91231 -21.12071 55.90642  1.000 65.24923  ? 81  PRO E C   1 
ATOM   5619 O  O   . PRO E 1 101 ? -29.28790 -21.78620 54.92868  1.000 62.22401  ? 81  PRO E O   1 
ATOM   5620 C  CB  . PRO E 1 101 ? -30.97216 -21.35628 57.34214  1.000 55.11442  ? 81  PRO E CB  1 
ATOM   5621 C  CG  . PRO E 1 101 ? -32.09879 -21.28189 56.36888  1.000 57.92990  ? 81  PRO E CG  1 
ATOM   5622 C  CD  . PRO E 1 101 ? -32.12046 -19.86124 55.87610  1.000 55.53700  ? 81  PRO E CD  1 
ATOM   5623 N  N   . PRO E 1 102 ? -27.62065 -21.01837 56.22367  1.000 63.75727  ? 82  PRO E N   1 
ATOM   5624 C  CA  . PRO E 1 102 ? -26.60127 -21.77503 55.49160  1.000 59.26299  ? 82  PRO E CA  1 
ATOM   5625 C  C   . PRO E 1 102 ? -26.42821 -23.20811 55.96483  1.000 47.87324  ? 82  PRO E C   1 
ATOM   5626 O  O   . PRO E 1 102 ? -25.43958 -23.84718 55.59810  1.000 46.77988  ? 82  PRO E O   1 
ATOM   5627 C  CB  . PRO E 1 102 ? -25.32888 -20.96022 55.75987  1.000 58.98836  ? 82  PRO E CB  1 
ATOM   5628 C  CG  . PRO E 1 102 ? -25.54351 -20.40512 57.12487  1.000 57.04148  ? 82  PRO E CG  1 
ATOM   5629 C  CD  . PRO E 1 102 ? -27.02924 -20.16913 57.27033  1.000 58.12913  ? 82  PRO E CD  1 
ATOM   5630 N  N   . PHE E 1 103 ? -27.35115 -23.71078 56.77599  1.000 50.79287  ? 83  PHE E N   1 
ATOM   5631 C  CA  . PHE E 1 103 ? -27.31097 -25.08152 57.25566  1.000 66.89123  ? 83  PHE E CA  1 
ATOM   5632 C  C   . PHE E 1 103 ? -28.74321 -25.56395 57.43973  1.000 73.24821  ? 83  PHE E C   1 
ATOM   5633 O  O   . PHE E 1 103 ? -29.69908 -24.78926 57.35556  1.000 73.94584  ? 83  PHE E O   1 
ATOM   5634 C  CB  . PHE E 1 103 ? -26.48965 -25.20348 58.54776  1.000 59.54385  ? 83  PHE E CB  1 
ATOM   5635 C  CG  . PHE E 1 103 ? -26.75121 -24.10684 59.54757  1.000 63.51648  ? 83  PHE E CG  1 
ATOM   5636 C  CD1 . PHE E 1 103 ? -27.66350 -24.29361 60.57350  1.000 68.50038  ? 83  PHE E CD1 1 
ATOM   5637 C  CD2 . PHE E 1 103 ? -26.07238 -22.89895 59.47103  1.000 62.36147  ? 83  PHE E CD2 1 
ATOM   5638 C  CE1 . PHE E 1 103 ? -27.90281 -23.29474 61.49994  1.000 70.09545  ? 83  PHE E CE1 1 
ATOM   5639 C  CE2 . PHE E 1 103 ? -26.31130 -21.89126 60.39381  1.000 69.52738  ? 83  PHE E CE2 1 
ATOM   5640 C  CZ  . PHE E 1 103 ? -27.22725 -22.09166 61.40997  1.000 62.85861  ? 83  PHE E CZ  1 
ATOM   5641 N  N   . ALA E 1 104 ? -28.88218 -26.86401 57.67846  1.000 69.71502  ? 84  ALA E N   1 
ATOM   5642 C  CA  . ALA E 1 104 ? -30.18769 -27.49625 57.81493  1.000 72.69110  ? 84  ALA E CA  1 
ATOM   5643 C  C   . ALA E 1 104 ? -30.64412 -27.41730 59.26769  1.000 73.03774  ? 84  ALA E C   1 
ATOM   5644 O  O   . ALA E 1 104 ? -30.01277 -28.00154 60.15553  1.000 76.75079  ? 84  ALA E O   1 
ATOM   5645 C  CB  . ALA E 1 104 ? -30.13346 -28.94859 57.34402  1.000 64.89230  ? 84  ALA E CB  1 
ATOM   5646 N  N   . ALA E 1 105 ? -31.74149 -26.70340 59.50491  1.000 77.28073  ? 85  ALA E N   1 
ATOM   5647 C  CA  . ALA E 1 105 ? -32.29127 -26.55067 60.84882  1.000 75.21780  ? 85  ALA E CA  1 
ATOM   5648 C  C   . ALA E 1 105 ? -33.59346 -27.33330 61.00072  1.000 72.14462  ? 85  ALA E C   1 
ATOM   5649 O  O   . ALA E 1 105 ? -34.67317 -26.75054 61.11703  1.000 64.07631  ? 85  ALA E O   1 
ATOM   5650 C  CB  . ALA E 1 105 ? -32.51623 -25.07777 61.16747  1.000 71.84562  ? 85  ALA E CB  1 
ATOM   5651 N  N   . PHE E 1 110 ? -34.08405 -23.05076 67.39010  1.000 79.59496  ? 90  PHE E N   1 
ATOM   5652 C  CA  . PHE E 1 110 ? -33.84379 -21.65207 67.71609  1.000 87.46598  ? 90  PHE E CA  1 
ATOM   5653 C  C   . PHE E 1 110 ? -35.07414 -20.99497 68.33590  1.000 80.07265  ? 90  PHE E C   1 
ATOM   5654 O  O   . PHE E 1 110 ? -36.20413 -21.38184 68.04093  1.000 83.42479  ? 90  PHE E O   1 
ATOM   5655 C  CB  . PHE E 1 110 ? -33.42384 -20.87273 66.46418  1.000 80.23463  ? 90  PHE E CB  1 
ATOM   5656 C  CG  . PHE E 1 110 ? -32.17704 -21.39035 65.81228  1.000 74.84168  ? 90  PHE E CG  1 
ATOM   5657 C  CD1 . PHE E 1 110 ? -30.93183 -21.11846 66.35282  1.000 72.48253  ? 90  PHE E CD1 1 
ATOM   5658 C  CD2 . PHE E 1 110 ? -32.24984 -22.14058 64.65023  1.000 74.07333  ? 90  PHE E CD2 1 
ATOM   5659 C  CE1 . PHE E 1 110 ? -29.78169 -21.59190 65.75065  1.000 65.80007  ? 90  PHE E CE1 1 
ATOM   5660 C  CE2 . PHE E 1 110 ? -31.10260 -22.61556 64.04332  1.000 75.92743  ? 90  PHE E CE2 1 
ATOM   5661 C  CZ  . PHE E 1 110 ? -29.86803 -22.34015 64.59403  1.000 67.34553  ? 90  PHE E CZ  1 
ATOM   5662 N  N   . PRO E 1 111 ? -34.85230 -20.00735 69.19803  1.000 80.98055  ? 91  PRO E N   1 
ATOM   5663 C  CA  . PRO E 1 111 ? -35.95850 -19.18444 69.68820  1.000 77.15380  ? 91  PRO E CA  1 
ATOM   5664 C  C   . PRO E 1 111 ? -36.58390 -18.39233 68.55531  1.000 79.85395  ? 91  PRO E C   1 
ATOM   5665 O  O   . PRO E 1 111 ? -35.92223 -18.11357 67.54422  1.000 81.08447  ? 91  PRO E O   1 
ATOM   5666 C  CB  . PRO E 1 111 ? -35.28351 -18.25622 70.70988  1.000 72.36670  ? 91  PRO E CB  1 
ATOM   5667 C  CG  . PRO E 1 111 ? -34.03435 -18.96191 71.11188  1.000 69.93931  ? 91  PRO E CG  1 
ATOM   5668 C  CD  . PRO E 1 111 ? -33.58432 -19.69487 69.87808  1.000 75.84075  ? 91  PRO E CD  1 
ATOM   5669 N  N   . PRO E 1 112 ? -37.85510 -18.01329 68.68071  1.000 79.91998  ? 92  PRO E N   1 
ATOM   5670 C  CA  . PRO E 1 112 ? -38.48755 -17.22358 67.61886  1.000 75.11969  ? 92  PRO E CA  1 
ATOM   5671 C  C   . PRO E 1 112 ? -37.81742 -15.86653 67.46045  1.000 74.14935  ? 92  PRO E C   1 
ATOM   5672 O  O   . PRO E 1 112 ? -37.32306 -15.27242 68.42212  1.000 77.06541  ? 92  PRO E O   1 
ATOM   5673 C  CB  . PRO E 1 112 ? -39.94072 -17.08165 68.09338  1.000 76.80661  ? 92  PRO E CB  1 
ATOM   5674 C  CG  . PRO E 1 112 ? -39.86997 -17.25717 69.57314  1.000 77.02021  ? 92  PRO E CG  1 
ATOM   5675 C  CD  . PRO E 1 112 ? -38.77069 -18.25459 69.80859  1.000 73.27635  ? 92  PRO E CD  1 
ATOM   5676 N  N   . ALA E 1 113 ? -37.80525 -15.37802 66.22151  1.000 62.10644  ? 93  ALA E N   1 
ATOM   5677 C  CA  . ALA E 1 113 ? -37.13764 -14.12513 65.90457  1.000 66.81379  ? 93  ALA E CA  1 
ATOM   5678 C  C   . ALA E 1 113 ? -37.86750 -13.43288 64.76447  1.000 63.28782  ? 93  ALA E C   1 
ATOM   5679 O  O   . ALA E 1 113 ? -38.46852 -14.08175 63.90326  1.000 65.46186  ? 93  ALA E O   1 
ATOM   5680 C  CB  . ALA E 1 113 ? -35.66834 -14.34852 65.53112  1.000 72.61662  ? 93  ALA E CB  1 
ATOM   5681 N  N   . GLU E 1 114 ? -37.80006 -12.10162 64.76946  1.000 64.54803  ? 94  GLU E N   1 
ATOM   5682 C  CA  . GLU E 1 114 ? -38.44767 -11.30508 63.73348  1.000 79.20048  ? 94  GLU E CA  1 
ATOM   5683 C  C   . GLU E 1 114 ? -37.57911 -11.20985 62.48518  1.000 77.96718  ? 94  GLU E C   1 
ATOM   5684 O  O   . GLU E 1 114 ? -38.03172 -11.52136 61.37787  1.000 79.36097  ? 94  GLU E O   1 
ATOM   5685 C  CB  . GLU E 1 114 ? -38.76487 -9.90688  64.27267  1.000 86.19672  ? 94  GLU E CB  1 
ATOM   5686 C  CG  . GLU E 1 114 ? -39.71544 -9.89258  65.46193  1.000 87.55370  ? 94  GLU E CG  1 
ATOM   5687 C  CD  . GLU E 1 114 ? -40.06029 -8.48498  65.90918  1.000 100.93026 ? 94  GLU E CD  1 
ATOM   5688 O  OE1 . GLU E 1 114 ? -39.48915 -7.52908  65.34468  1.000 107.67830 ? 94  GLU E OE1 1 
ATOM   5689 O  OE2 . GLU E 1 114 ? -40.90199 -8.33146  66.81985  1.000 103.23136 ? 94  GLU E OE2 1 
ATOM   5690 N  N   . ARG E 1 115 ? -36.32796 -10.78185 62.64782  1.000 72.15367  ? 95  ARG E N   1 
ATOM   5691 C  CA  . ARG E 1 115 ? -35.37242 -10.65123 61.54667  1.000 78.10325  ? 95  ARG E CA  1 
ATOM   5692 C  C   . ARG E 1 115 ? -34.04787 -11.28488 61.95458  1.000 68.03770  ? 95  ARG E C   1 
ATOM   5693 O  O   . ARG E 1 115 ? -33.06867 -10.58413 62.23519  1.000 57.92159  ? 95  ARG E O   1 
ATOM   5694 C  CB  . ARG E 1 115 ? -35.17597 -9.18396  61.16148  1.000 80.02858  ? 95  ARG E CB  1 
ATOM   5695 C  CG  . ARG E 1 115 ? -36.45297 -8.45700  60.77502  1.000 81.91140  ? 95  ARG E CG  1 
ATOM   5696 C  CD  . ARG E 1 115 ? -36.15364 -7.04151  60.30990  1.000 79.81609  ? 95  ARG E CD  1 
ATOM   5697 N  NE  . ARG E 1 115 ? -35.24614 -7.03042  59.16873  1.000 79.71889  ? 95  ARG E NE  1 
ATOM   5698 C  CZ  . ARG E 1 115 ? -35.63407 -7.10521  57.90281  1.000 87.17828  ? 95  ARG E CZ  1 
ATOM   5699 N  NH1 . ARG E 1 115 ? -36.91363 -7.18607  57.57540  1.000 86.76978  ? 95  ARG E NH1 1 
ATOM   5700 N  NH2 . ARG E 1 115 ? -34.71523 -7.10129  56.94111  1.000 72.22971  ? 95  ARG E NH2 1 
ATOM   5701 N  N   . PRO E 1 116 ? -33.98316 -12.61441 62.00429  1.000 68.10438  ? 96  PRO E N   1 
ATOM   5702 C  CA  . PRO E 1 116 ? -32.73488 -13.27099 62.40593  1.000 64.94389  ? 96  PRO E CA  1 
ATOM   5703 C  C   . PRO E 1 116 ? -31.75516 -13.38207 61.24763  1.000 64.49524  ? 96  PRO E C   1 
ATOM   5704 O  O   . PRO E 1 116 ? -32.13421 -13.65307 60.10509  1.000 66.71347  ? 96  PRO E O   1 
ATOM   5705 C  CB  . PRO E 1 116 ? -33.20360 -14.65481 62.86867  1.000 61.88367  ? 96  PRO E CB  1 
ATOM   5706 C  CG  . PRO E 1 116 ? -34.39960 -14.92405 62.01764  1.000 61.66248  ? 96  PRO E CG  1 
ATOM   5707 C  CD  . PRO E 1 116 ? -35.06225 -13.58891 61.75767  1.000 65.39888  ? 96  PRO E CD  1 
ATOM   5708 N  N   . LEU E 1 117 ? -30.48099 -13.16395 61.55558  1.000 56.26544  ? 97  LEU E N   1 
ATOM   5709 C  CA  . LEU E 1 117 ? -29.39489 -13.40799 60.62148  1.000 50.35130  ? 97  LEU E CA  1 
ATOM   5710 C  C   . LEU E 1 117 ? -28.60250 -14.62852 61.06904  1.000 55.55583  ? 97  LEU E C   1 
ATOM   5711 O  O   . LEU E 1 117 ? -28.66980 -15.05291 62.22561  1.000 54.56741  ? 97  LEU E O   1 
ATOM   5712 C  CB  . LEU E 1 117 ? -28.47130 -12.18944 60.50228  1.000 45.09841  ? 97  LEU E CB  1 
ATOM   5713 C  CG  . LEU E 1 117 ? -29.04837 -10.97988 59.76208  1.000 47.30924  ? 97  LEU E CG  1 
ATOM   5714 C  CD1 . LEU E 1 117 ? -29.71619 -10.02685 60.73221  1.000 50.15380  ? 97  LEU E CD1 1 
ATOM   5715 C  CD2 . LEU E 1 117 ? -27.98065 -10.26229 58.94987  1.000 49.13797  ? 97  LEU E CD2 1 
ATOM   5716 N  N   . TYR E 1 118 ? -27.84719 -15.19301 60.13245  1.000 56.89316  ? 98  TYR E N   1 
ATOM   5717 C  CA  . TYR E 1 118 ? -27.11223 -16.42866 60.34771  1.000 49.98581  ? 98  TYR E CA  1 
ATOM   5718 C  C   . TYR E 1 118 ? -25.62278 -16.17671 60.18094  1.000 44.82991  ? 98  TYR E C   1 
ATOM   5719 O  O   . TYR E 1 118 ? -25.19718 -15.55482 59.19803  1.000 43.84893  ? 98  TYR E O   1 
ATOM   5720 C  CB  . TYR E 1 118 ? -27.57179 -17.51483 59.37770  1.000 53.28407  ? 98  TYR E CB  1 
ATOM   5721 C  CG  . TYR E 1 118 ? -28.96072 -18.03914 59.64844  1.000 57.60178  ? 98  TYR E CG  1 
ATOM   5722 C  CD1 . TYR E 1 118 ? -30.08030 -17.38415 59.15521  1.000 58.91263  ? 98  TYR E CD1 1 
ATOM   5723 C  CD2 . TYR E 1 118 ? -29.15245 -19.19443 60.39495  1.000 62.24983  ? 98  TYR E CD2 1 
ATOM   5724 C  CE1 . TYR E 1 118 ? -31.35245 -17.86180 59.39866  1.000 58.16796  ? 98  TYR E CE1 1 
ATOM   5725 C  CE2 . TYR E 1 118 ? -30.42105 -19.68065 60.64468  1.000 59.87195  ? 98  TYR E CE2 1 
ATOM   5726 C  CZ  . TYR E 1 118 ? -31.51789 -19.00988 60.14352  1.000 58.69128  ? 98  TYR E CZ  1 
ATOM   5727 O  OH  . TYR E 1 118 ? -32.78517 -19.48784 60.38756  1.000 72.98111  ? 98  TYR E OH  1 
ATOM   5728 N  N   . LEU E 1 119 ? -24.84621 -16.66442 61.14518  1.000 40.35881  ? 99  LEU E N   1 
ATOM   5729 C  CA  . LEU E 1 119 ? -23.39312 -16.58642 61.13537  1.000 45.93967  ? 99  LEU E CA  1 
ATOM   5730 C  C   . LEU E 1 119 ? -22.81795 -17.95731 60.80399  1.000 41.59742  ? 99  LEU E C   1 
ATOM   5731 O  O   . LEU E 1 119 ? -23.18442 -18.95708 61.43096  1.000 39.60494  ? 99  LEU E O   1 
ATOM   5732 C  CB  . LEU E 1 119 ? -22.87064 -16.11053 62.49204  1.000 39.26036  ? 99  LEU E CB  1 
ATOM   5733 C  CG  . LEU E 1 119 ? -21.39234 -16.37503 62.78236  1.000 34.92836  ? 99  LEU E CG  1 
ATOM   5734 C  CD1 . LEU E 1 119 ? -20.49612 -15.38561 62.04666  1.000 30.84779  ? 99  LEU E CD1 1 
ATOM   5735 C  CD2 . LEU E 1 119 ? -21.13131 -16.34865 64.27902  1.000 35.14654  ? 99  LEU E CD2 1 
ATOM   5736 N  N   . SER E 1 120 ? -21.91645 -18.00102 59.82622  1.000 39.55021  ? 100 SER E N   1 
ATOM   5737 C  CA  . SER E 1 120 ? -21.28731 -19.25102 59.42681  1.000 37.62958  ? 100 SER E CA  1 
ATOM   5738 C  C   . SER E 1 120 ? -19.85801 -18.97376 58.98183  1.000 34.57708  ? 100 SER E C   1 
ATOM   5739 O  O   . SER E 1 120 ? -19.43678 -17.82145 58.84075  1.000 33.83425  ? 100 SER E O   1 
ATOM   5740 C  CB  . SER E 1 120 ? -22.07974 -19.94885 58.31177  1.000 32.94798  ? 100 SER E CB  1 
ATOM   5741 O  OG  . SER E 1 120 ? -22.16943 -19.13551 57.15508  1.000 37.90350  ? 100 SER E OG  1 
ATOM   5742 N  N   . ARG E 1 121 ? -19.10600 -20.05870 58.79213  1.000 38.65480  ? 101 ARG E N   1 
ATOM   5743 C  CA  . ARG E 1 121 ? -17.77440 -20.00804 58.18817  1.000 33.87737  ? 101 ARG E CA  1 
ATOM   5744 C  C   . ARG E 1 121 ? -16.87416 -18.98335 58.87390  1.000 33.15214  ? 101 ARG E C   1 
ATOM   5745 O  O   . ARG E 1 121 ? -16.13827 -18.23802 58.22411  1.000 31.41927  ? 101 ARG E O   1 
ATOM   5746 C  CB  . ARG E 1 121 ? -17.86884 -19.72953 56.68856  1.000 34.07783  ? 101 ARG E CB  1 
ATOM   5747 C  CG  . ARG E 1 121 ? -18.46543 -20.86738 55.88594  1.000 31.28947  ? 101 ARG E CG  1 
ATOM   5748 C  CD  . ARG E 1 121 ? -18.37069 -20.57248 54.40359  1.000 35.10149  ? 101 ARG E CD  1 
ATOM   5749 N  NE  . ARG E 1 121 ? -18.31867 -21.78880 53.60377  1.000 34.89166  ? 101 ARG E NE  1 
ATOM   5750 C  CZ  . ARG E 1 121 ? -17.79634 -21.85576 52.38674  1.000 39.75027  ? 101 ARG E CZ  1 
ATOM   5751 N  NH1 . ARG E 1 121 ? -17.25978 -20.79477 51.80624  1.000 30.88289  ? 101 ARG E NH1 1 
ATOM   5752 N  NH2 . ARG E 1 121 ? -17.79877 -23.01907 51.74217  1.000 42.44123  ? 101 ARG E NH2 1 
ATOM   5753 N  N   . LEU E 1 122 ? -16.94920 -18.93173 60.20135  1.000 46.35046  ? 102 LEU E N   1 
ATOM   5754 C  CA  . LEU E 1 122 ? -16.00575 -18.13242 60.96966  1.000 40.33491  ? 102 LEU E CA  1 
ATOM   5755 C  C   . LEU E 1 122 ? -14.62470 -18.76767 60.88165  1.000 36.72261  ? 102 LEU E C   1 
ATOM   5756 O  O   . LEU E 1 122 ? -14.45610 -19.95153 61.18663  1.000 44.96856  ? 102 LEU E O   1 
ATOM   5757 C  CB  . LEU E 1 122 ? -16.45693 -18.03038 62.42464  1.000 38.05368  ? 102 LEU E CB  1 
ATOM   5758 C  CG  . LEU E 1 122 ? -15.61731 -17.15033 63.35221  1.000 42.13655  ? 102 LEU E CG  1 
ATOM   5759 C  CD1 . LEU E 1 122 ? -15.90591 -15.67868 63.09650  1.000 36.84507  ? 102 LEU E CD1 1 
ATOM   5760 C  CD2 . LEU E 1 122 ? -15.86279 -17.51092 64.81068  1.000 36.80994  ? 102 LEU E CD2 1 
ATOM   5761 N  N   . ALA E 1 123 ? -13.63611 -17.99094 60.44936  1.000 34.20978  ? 103 ALA E N   1 
ATOM   5762 C  CA  . ALA E 1 123 ? -12.31446 -18.55047 60.21632  1.000 39.69308  ? 103 ALA E CA  1 
ATOM   5763 C  C   . ALA E 1 123 ? -11.25362 -17.51563 60.55494  1.000 36.59662  ? 103 ALA E C   1 
ATOM   5764 O  O   . ALA E 1 123 ? -11.43343 -16.32293 60.29920  1.000 37.65043  ? 103 ALA E O   1 
ATOM   5765 C  CB  . ALA E 1 123 ? -12.16131 -19.02138 58.76441  1.000 36.91235  ? 103 ALA E CB  1 
ATOM   5766 N  N   . VAL E 1 124 ? -10.15621 -17.98442 61.14160  1.000 41.66045  ? 104 VAL E N   1 
ATOM   5767 C  CA  . VAL E 1 124 ? -8.99349  -17.16118 61.44829  1.000 40.92448  ? 104 VAL E CA  1 
ATOM   5768 C  C   . VAL E 1 124 ? -7.77151  -17.84317 60.85330  1.000 36.87982  ? 104 VAL E C   1 
ATOM   5769 O  O   . VAL E 1 124 ? -7.63449  -19.06805 60.94076  1.000 42.68886  ? 104 VAL E O   1 
ATOM   5770 C  CB  . VAL E 1 124 ? -8.82074  -16.95013 62.97011  1.000 42.03324  ? 104 VAL E CB  1 
ATOM   5771 C  CG1 . VAL E 1 124 ? -7.44597  -16.37558 63.28207  1.000 47.59255  ? 104 VAL E CG1 1 
ATOM   5772 C  CG2 . VAL E 1 124 ? -9.90585  -16.03276 63.50766  1.000 32.76194  ? 104 VAL E CG2 1 
ATOM   5773 N  N   . ALA E 1 125 ? -6.89961  -17.05692 60.23031  1.000 40.50517  ? 105 ALA E N   1 
ATOM   5774 C  CA  . ALA E 1 125 ? -5.68733  -17.61266 59.65008  1.000 45.15838  ? 105 ALA E CA  1 
ATOM   5775 C  C   . ALA E 1 125 ? -4.87827  -18.33611 60.72524  1.000 45.40916  ? 105 ALA E C   1 
ATOM   5776 O  O   . ALA E 1 125 ? -4.81352  -17.87169 61.86971  1.000 50.84979  ? 105 ALA E O   1 
ATOM   5777 C  CB  . ALA E 1 125 ? -4.84711  -16.50941 59.00613  1.000 40.25112  ? 105 ALA E CB  1 
ATOM   5778 N  N   . PRO E 1 126 ? -4.26522  -19.47870 60.39955  1.000 46.75177  ? 106 PRO E N   1 
ATOM   5779 C  CA  . PRO E 1 126 ? -3.52648  -20.23917 61.42531  1.000 55.07061  ? 106 PRO E CA  1 
ATOM   5780 C  C   . PRO E 1 126 ? -2.42415  -19.44631 62.10982  1.000 58.05336  ? 106 PRO E C   1 
ATOM   5781 O  O   . PRO E 1 126 ? -2.07568  -19.75018 63.25815  1.000 58.88065  ? 106 PRO E O   1 
ATOM   5782 C  CB  . PRO E 1 126 ? -2.95437  -21.42231 60.63171  1.000 56.10410  ? 106 PRO E CB  1 
ATOM   5783 C  CG  . PRO E 1 126 ? -3.87058  -21.57435 59.46258  1.000 46.34879  ? 106 PRO E CG  1 
ATOM   5784 C  CD  . PRO E 1 126 ? -4.31180  -20.18389 59.10695  1.000 49.04678  ? 106 PRO E CD  1 
ATOM   5785 N  N   . GLU E 1 127 ? -1.86849  -18.43440 61.44026  1.000 58.68605  ? 107 GLU E N   1 
ATOM   5786 C  CA  . GLU E 1 127 ? -0.80829  -17.62295 62.02530  1.000 57.49106  ? 107 GLU E CA  1 
ATOM   5787 C  C   . GLU E 1 127 ? -1.29962  -16.77043 63.18892  1.000 61.16168  ? 107 GLU E C   1 
ATOM   5788 O  O   . GLU E 1 127 ? -0.47818  -16.27014 63.96503  1.000 53.36013  ? 107 GLU E O   1 
ATOM   5789 C  CB  . GLU E 1 127 ? -0.18216  -16.73743 60.94436  1.000 56.82064  ? 107 GLU E CB  1 
ATOM   5790 C  CG  . GLU E 1 127 ? -1.17330  -16.23897 59.88541  1.000 69.47441  ? 107 GLU E CG  1 
ATOM   5791 C  CD  . GLU E 1 127 ? -1.43188  -17.25188 58.76975  1.000 74.89135  ? 107 GLU E CD  1 
ATOM   5792 O  OE1 . GLU E 1 127 ? -1.57012  -16.83001 57.60260  1.000 72.49842  ? 107 GLU E OE1 1 
ATOM   5793 O  OE2 . GLU E 1 127 ? -1.50558  -18.46700 59.05820  1.000 72.88806  ? 107 GLU E OE2 1 
ATOM   5794 N  N   . TRP E 1 128 ? -2.61113  -16.59255 63.32888  1.000 59.20953  ? 108 TRP E N   1 
ATOM   5795 C  CA  . TRP E 1 128 ? -3.18258  -15.86076 64.44964  1.000 59.25344  ? 108 TRP E CA  1 
ATOM   5796 C  C   . TRP E 1 128 ? -3.80948  -16.77418 65.49286  1.000 57.80921  ? 108 TRP E C   1 
ATOM   5797 O  O   . TRP E 1 128 ? -4.30180  -16.28138 66.51283  1.000 63.69594  ? 108 TRP E O   1 
ATOM   5798 C  CB  . TRP E 1 128 ? -4.22956  -14.86105 63.94981  1.000 62.73992  ? 108 TRP E CB  1 
ATOM   5799 C  CG  . TRP E 1 128 ? -3.67760  -13.80971 63.04119  1.000 55.80505  ? 108 TRP E CG  1 
ATOM   5800 C  CD1 . TRP E 1 128 ? -3.89516  -13.69054 61.70051  1.000 50.09164  ? 108 TRP E CD1 1 
ATOM   5801 C  CD2 . TRP E 1 128 ? -2.81531  -12.72617 63.40651  1.000 53.98844  ? 108 TRP E CD2 1 
ATOM   5802 N  NE1 . TRP E 1 128 ? -3.22395  -12.59848 61.20711  1.000 53.13612  ? 108 TRP E NE1 1 
ATOM   5803 C  CE2 . TRP E 1 128 ? -2.55229  -11.98974 62.23459  1.000 50.96957  ? 108 TRP E CE2 1 
ATOM   5804 C  CE3 . TRP E 1 128 ? -2.24123  -12.30664 64.61051  1.000 50.78385  ? 108 TRP E CE3 1 
ATOM   5805 C  CZ2 . TRP E 1 128 ? -1.73942  -10.85881 62.23087  1.000 63.08182  ? 108 TRP E CZ2 1 
ATOM   5806 C  CZ3 . TRP E 1 128 ? -1.43426  -11.18286 64.60490  1.000 45.48087  ? 108 TRP E CZ3 1 
ATOM   5807 C  CH2 . TRP E 1 128 ? -1.19050  -10.47205 63.42352  1.000 56.12806  ? 108 TRP E CH2 1 
ATOM   5808 N  N   . LEU E 1 129 ? -3.80456  -18.08419 65.26489  1.000 59.86107  ? 109 LEU E N   1 
ATOM   5809 C  CA  . LEU E 1 129 ? -4.36264  -19.04810 66.21370  1.000 70.49183  ? 109 LEU E CA  1 
ATOM   5810 C  C   . LEU E 1 129 ? -3.31009  -19.52193 67.21144  1.000 74.26308  ? 109 LEU E C   1 
ATOM   5811 O  O   . LEU E 1 129 ? -3.07946  -20.71679 67.39292  1.000 79.44531  ? 109 LEU E O   1 
ATOM   5812 C  CB  . LEU E 1 129 ? -4.97813  -20.22143 65.45980  1.000 63.50713  ? 109 LEU E CB  1 
ATOM   5813 C  CG  . LEU E 1 129 ? -6.25658  -19.88784 64.68666  1.000 59.70234  ? 109 LEU E CG  1 
ATOM   5814 C  CD1 . LEU E 1 129 ? -6.86787  -21.12990 64.04624  1.000 52.11901  ? 109 LEU E CD1 1 
ATOM   5815 C  CD2 . LEU E 1 129 ? -7.26039  -19.19758 65.60078  1.000 53.22443  ? 109 LEU E CD2 1 
ATOM   5816 N  N   . THR E 1 130 ? -2.65900  -18.56699 67.86728  1.000 86.03756  ? 110 THR E N   1 
ATOM   5817 C  CA  . THR E 1 130 ? -1.61746  -18.86648 68.84256  1.000 90.84410  ? 110 THR E CA  1 
ATOM   5818 C  C   . THR E 1 130 ? -1.75862  -17.98615 70.08115  1.000 90.76469  ? 110 THR E C   1 
ATOM   5819 O  O   . THR E 1 130 ? -2.60101  -18.23728 70.94281  1.000 98.81285  ? 110 THR E O   1 
ATOM   5820 C  CB  . THR E 1 130 ? -0.21061  -18.67275 68.24456  1.000 83.52471  ? 110 THR E CB  1 
ATOM   5821 O  OG1 . THR E 1 130 ? -0.14371  -17.40635 67.57671  1.000 83.16589  ? 110 THR E OG1 1 
ATOM   5822 C  CG2 . THR E 1 130 ? 0.11451   -19.78538 67.25705  1.000 81.46714  ? 110 THR E CG2 1 
ATOM   5823 N  N   . LEU E 1 134 ? -7.67746  -13.47855 69.91349  1.000 49.44671  ? 114 LEU E N   1 
ATOM   5824 C  CA  . LEU E 1 134 ? -8.07919  -12.08365 69.77273  1.000 45.04593  ? 114 LEU E CA  1 
ATOM   5825 C  C   . LEU E 1 134 ? -8.72198  -11.81842 68.41463  1.000 46.15602  ? 114 LEU E C   1 
ATOM   5826 O  O   . LEU E 1 134 ? -9.71251  -11.09465 68.32219  1.000 50.31765  ? 114 LEU E O   1 
ATOM   5827 C  CB  . LEU E 1 134 ? -6.87674  -11.15616 69.96974  1.000 53.18451  ? 114 LEU E CB  1 
ATOM   5828 C  CG  . LEU E 1 134 ? -6.28233  -11.07638 71.37470  1.000 54.80665  ? 114 LEU E CG  1 
ATOM   5829 C  CD1 . LEU E 1 134 ? -5.05908  -10.17059 71.39312  1.000 61.10830  ? 114 LEU E CD1 1 
ATOM   5830 C  CD2 . LEU E 1 134 ? -7.32982  -10.58020 72.35099  1.000 52.03606  ? 114 LEU E CD2 1 
ATOM   5831 N  N   . VAL E 1 135 ? -8.14711  -12.40608 67.36203  1.000 46.55749  ? 115 VAL E N   1 
ATOM   5832 C  CA  . VAL E 1 135 ? -8.66529  -12.19007 66.01364  1.000 52.41326  ? 115 VAL E CA  1 
ATOM   5833 C  C   . VAL E 1 135 ? -10.05743 -12.79240 65.87294  1.000 40.47812  ? 115 VAL E C   1 
ATOM   5834 O  O   . VAL E 1 135 ? -10.95155 -12.18895 65.26642  1.000 36.78373  ? 115 VAL E O   1 
ATOM   5835 C  CB  . VAL E 1 135 ? -7.68890  -12.75973 64.96823  1.000 47.92666  ? 115 VAL E CB  1 
ATOM   5836 C  CG1 . VAL E 1 135 ? -8.14950  -12.40592 63.56133  1.000 42.68268  ? 115 VAL E CG1 1 
ATOM   5837 C  CG2 . VAL E 1 135 ? -6.28292  -12.23966 65.22244  1.000 53.77353  ? 115 VAL E CG2 1 
ATOM   5838 N  N   . GLY E 1 136 ? -10.26424 -13.98921 66.42512  1.000 38.32574  ? 116 GLY E N   1 
ATOM   5839 C  CA  . GLY E 1 136 ? -11.60607 -14.54487 66.46787  1.000 39.45240  ? 116 GLY E CA  1 
ATOM   5840 C  C   . GLY E 1 136 ? -12.56849 -13.66114 67.23694  1.000 41.95017  ? 116 GLY E C   1 
ATOM   5841 O  O   . GLY E 1 136 ? -13.73745 -13.53010 66.86716  1.000 41.33817  ? 116 GLY E O   1 
ATOM   5842 N  N   . LEU E 1 137 ? -12.08324 -13.02787 68.30852  1.000 43.78383  ? 117 LEU E N   1 
ATOM   5843 C  CA  . LEU E 1 137 ? -12.91197 -12.09021 69.05912  1.000 37.16755  ? 117 LEU E CA  1 
ATOM   5844 C  C   . LEU E 1 137 ? -13.27048 -10.87374 68.21606  1.000 42.59789  ? 117 LEU E C   1 
ATOM   5845 O  O   . LEU E 1 137 ? -14.41715 -10.40980 68.24139  1.000 39.17782  ? 117 LEU E O   1 
ATOM   5846 C  CB  . LEU E 1 137 ? -12.18995 -11.66355 70.33593  1.000 43.73682  ? 117 LEU E CB  1 
ATOM   5847 C  CG  . LEU E 1 137 ? -12.79714 -10.50949 71.13480  1.000 36.42029  ? 117 LEU E CG  1 
ATOM   5848 C  CD1 . LEU E 1 137 ? -14.16087 -10.88734 71.69994  1.000 36.23478  ? 117 LEU E CD1 1 
ATOM   5849 C  CD2 . LEU E 1 137 ? -11.84584 -10.09262 72.24097  1.000 35.89863  ? 117 LEU E CD2 1 
ATOM   5850 N  N   . ARG E 1 138 ? -12.29795 -10.33624 67.47302  1.000 42.54352  ? 118 ARG E N   1 
ATOM   5851 C  CA  . ARG E 1 138 ? -12.57941 -9.22959  66.56432  1.000 38.04980  ? 118 ARG E CA  1 
ATOM   5852 C  C   . ARG E 1 138 ? -13.63916 -9.62101  65.54267  1.000 39.28194  ? 118 ARG E C   1 
ATOM   5853 O  O   . ARG E 1 138 ? -14.58001 -8.86088  65.28369  1.000 47.46982  ? 118 ARG E O   1 
ATOM   5854 C  CB  . ARG E 1 138 ? -11.29767 -8.78664  65.85483  1.000 42.63989  ? 118 ARG E CB  1 
ATOM   5855 C  CG  . ARG E 1 138 ? -10.15683 -8.39164  66.77114  1.000 48.75888  ? 118 ARG E CG  1 
ATOM   5856 C  CD  . ARG E 1 138 ? -8.92620  -7.97292  65.97481  1.000 51.49047  ? 118 ARG E CD  1 
ATOM   5857 N  NE  . ARG E 1 138 ? -9.00715  -6.59007  65.51729  1.000 60.55507  ? 118 ARG E NE  1 
ATOM   5858 C  CZ  . ARG E 1 138 ? -8.31514  -5.58745  66.04242  1.000 59.48824  ? 118 ARG E CZ  1 
ATOM   5859 N  NH1 . ARG E 1 138 ? -7.45361  -5.78374  67.02703  1.000 57.98512  ? 118 ARG E NH1 1 
ATOM   5860 N  NH2 . ARG E 1 138 ? -8.48802  -4.35789  65.56476  1.000 58.04764  ? 118 ARG E NH2 1 
ATOM   5861 N  N   . CYS E 1 139 ? -13.49930 -10.81273 64.95253  1.000 37.78420  ? 119 CYS E N   1 
ATOM   5862 C  CA  . CYS E 1 139 ? -14.44540 -11.25767 63.93394  1.000 41.17578  ? 119 CYS E CA  1 
ATOM   5863 C  C   . CYS E 1 139 ? -15.83866 -11.44490 64.51746  1.000 39.25754  ? 119 CYS E C   1 
ATOM   5864 O  O   . CYS E 1 139 ? -16.83674 -11.06916 63.89341  1.000 38.11249  ? 119 CYS E O   1 
ATOM   5865 C  CB  . CYS E 1 139 ? -13.95697 -12.55740 63.29217  1.000 34.65091  ? 119 CYS E CB  1 
ATOM   5866 S  SG  . CYS E 1 139 ? -12.38407 -12.42141 62.42300  1.000 38.46142  ? 119 CYS E SG  1 
ATOM   5867 N  N   . LEU E 1 140 ? -15.92743 -12.01848 65.71757  1.000 41.65774  ? 120 LEU E N   1 
ATOM   5868 C  CA  . LEU E 1 140 ? -17.23176 -12.25771 66.32202  1.000 38.61595  ? 120 LEU E CA  1 
ATOM   5869 C  C   . LEU E 1 140 ? -17.90058 -10.94972 66.73288  1.000 47.14479  ? 120 LEU E C   1 
ATOM   5870 O  O   . LEU E 1 140 ? -19.11428 -10.78769 66.55604  1.000 46.22657  ? 120 LEU E O   1 
ATOM   5871 C  CB  . LEU E 1 140 ? -17.08113 -13.20051 67.51347  1.000 35.43564  ? 120 LEU E CB  1 
ATOM   5872 C  CG  . LEU E 1 140 ? -18.27009 -14.12417 67.77521  1.000 48.32993  ? 120 LEU E CG  1 
ATOM   5873 C  CD1 . LEU E 1 140 ? -18.72512 -14.79156 66.48446  1.000 44.53272  ? 120 LEU E CD1 1 
ATOM   5874 C  CD2 . LEU E 1 140 ? -17.90109 -15.16706 68.81474  1.000 55.38367  ? 120 LEU E CD2 1 
ATOM   5875 N  N   . ARG E 1 141 ? -17.12832 -10.00075 67.27485  1.000 46.74385  ? 121 ARG E N   1 
ATOM   5876 C  CA  . ARG E 1 141 ? -17.68038 -8.68167  67.57268  1.000 47.49352  ? 121 ARG E CA  1 
ATOM   5877 C  C   . ARG E 1 141 ? -18.16850 -7.99589  66.30528  1.000 43.09431  ? 121 ARG E C   1 
ATOM   5878 O  O   . ARG E 1 141 ? -19.25226 -7.39681  66.28980  1.000 43.45556  ? 121 ARG E O   1 
ATOM   5879 C  CB  . ARG E 1 141 ? -16.63513 -7.81202  68.27263  1.000 43.00099  ? 121 ARG E CB  1 
ATOM   5880 C  CG  . ARG E 1 141 ? -16.42158 -8.13116  69.73862  1.000 47.56653  ? 121 ARG E CG  1 
ATOM   5881 C  CD  . ARG E 1 141 ? -15.36828 -7.21594  70.34198  1.000 50.26943  ? 121 ARG E CD  1 
ATOM   5882 N  NE  . ARG E 1 141 ? -15.72547 -5.80624  70.23333  1.000 49.40861  ? 121 ARG E NE  1 
ATOM   5883 C  CZ  . ARG E 1 141 ? -16.37958 -5.12458  71.16392  1.000 52.14830  ? 121 ARG E CZ  1 
ATOM   5884 N  NH1 . ARG E 1 141 ? -16.78704 -5.69971  72.28268  1.000 48.85384  ? 121 ARG E NH1 1 
ATOM   5885 N  NH2 . ARG E 1 141 ? -16.62889 -3.83243  70.96794  1.000 43.47635  ? 121 ARG E NH2 1 
ATOM   5886 N  N   . ARG E 1 142 ? -17.37809 -8.07389  65.23088  1.000 46.76329  ? 122 ARG E N   1 
ATOM   5887 C  CA  . ARG E 1 142 ? -17.78413 -7.47935  63.96422  1.000 43.94889  ? 122 ARG E CA  1 
ATOM   5888 C  C   . ARG E 1 142 ? -19.06695 -8.11331  63.44705  1.000 37.94142  ? 122 ARG E C   1 
ATOM   5889 O  O   . ARG E 1 142 ? -19.94805 -7.41368  62.94134  1.000 45.54354  ? 122 ARG E O   1 
ATOM   5890 C  CB  . ARG E 1 142 ? -16.66291 -7.62471  62.93754  1.000 43.28712  ? 122 ARG E CB  1 
ATOM   5891 C  CG  . ARG E 1 142 ? -16.92882 -6.92979  61.61271  1.000 45.64904  ? 122 ARG E CG  1 
ATOM   5892 C  CD  . ARG E 1 142 ? -16.77231 -5.42676  61.74668  1.000 44.63920  ? 122 ARG E CD  1 
ATOM   5893 N  NE  . ARG E 1 142 ? -16.81615 -4.75416  60.45393  1.000 52.18540  ? 122 ARG E NE  1 
ATOM   5894 C  CZ  . ARG E 1 142 ? -16.49037 -3.48317  60.26437  1.000 53.72584  ? 122 ARG E CZ  1 
ATOM   5895 N  NH1 . ARG E 1 142 ? -16.09253 -2.71552  61.26609  1.000 53.31762  ? 122 ARG E NH1 1 
ATOM   5896 N  NH2 . ARG E 1 142 ? -16.55938 -2.97124  59.03904  1.000 44.86278  ? 122 ARG E NH2 1 
ATOM   5897 N  N   . ALA E 1 143 ? -19.19797 -9.43607  63.58018  1.000 37.19255  ? 123 ALA E N   1 
ATOM   5898 C  CA  . ALA E 1 143 ? -20.40236 -10.11017 63.10268  1.000 45.32600  ? 123 ALA E CA  1 
ATOM   5899 C  C   . ALA E 1 143 ? -21.62320 -9.71774  63.92555  1.000 47.38936  ? 123 ALA E C   1 
ATOM   5900 O  O   . ALA E 1 143 ? -22.69637 -9.46238  63.36678  1.000 43.54200  ? 123 ALA E O   1 
ATOM   5901 C  CB  . ALA E 1 143 ? -20.20610 -11.62591 63.12438  1.000 30.65124  ? 123 ALA E CB  1 
ATOM   5902 N  N   . ILE E 1 144 ? -21.48055 -9.67156  65.25286  1.000 42.30455  ? 124 ILE E N   1 
ATOM   5903 C  CA  . ILE E 1 144 ? -22.59039 -9.26330  66.11243  1.000 42.65880  ? 124 ILE E CA  1 
ATOM   5904 C  C   . ILE E 1 144 ? -23.04180 -7.85085  65.75580  1.000 44.98250  ? 124 ILE E C   1 
ATOM   5905 O  O   . ILE E 1 144 ? -24.23896 -7.58485  65.57615  1.000 37.45129  ? 124 ILE E O   1 
ATOM   5906 C  CB  . ILE E 1 144 ? -22.18531 -9.37313  67.59511  1.000 48.61521  ? 124 ILE E CB  1 
ATOM   5907 C  CG1 . ILE E 1 144 ? -21.94291 -10.83685 67.98124  1.000 46.01961  ? 124 ILE E CG1 1 
ATOM   5908 C  CG2 . ILE E 1 144 ? -23.23673 -8.73235  68.49550  1.000 39.50982  ? 124 ILE E CG2 1 
ATOM   5909 C  CD1 . ILE E 1 144 ? -21.21975 -11.01292 69.30851  1.000 40.27062  ? 124 ILE E CD1 1 
ATOM   5910 N  N   . GLU E 1 145 ? -22.08133 -6.92771  65.62743  1.000 53.03954  ? 125 GLU E N   1 
ATOM   5911 C  CA  . GLU E 1 145 ? -22.41087 -5.54070  65.31227  1.000 40.26138  ? 125 GLU E CA  1 
ATOM   5912 C  C   . GLU E 1 145 ? -23.02375 -5.40694  63.92245  1.000 53.64190  ? 125 GLU E C   1 
ATOM   5913 O  O   . GLU E 1 145 ? -23.95341 -4.61773  63.72709  1.000 58.18426  ? 125 GLU E O   1 
ATOM   5914 C  CB  . GLU E 1 145 ? -21.16196 -4.66786  65.43146  1.000 46.40759  ? 125 GLU E CB  1 
ATOM   5915 C  CG  . GLU E 1 145 ? -20.62540 -4.54776  66.84768  1.000 59.61403  ? 125 GLU E CG  1 
ATOM   5916 C  CD  . GLU E 1 145 ? -19.35791 -3.71621  66.92738  1.000 63.62259  ? 125 GLU E CD  1 
ATOM   5917 O  OE1 . GLU E 1 145 ? -18.85790 -3.28142  65.86646  1.000 62.30237  ? 125 GLU E OE1 1 
ATOM   5918 O  OE2 . GLU E 1 145 ? -18.86304 -3.49951  68.05481  1.000 59.66384  ? 125 GLU E OE2 1 
ATOM   5919 N  N   . THR E 1 146 ? -22.50832 -6.15321  62.94091  1.000 50.75237  ? 126 THR E N   1 
ATOM   5920 C  CA  . THR E 1 146 ? -23.05831 -6.09197  61.59129  1.000 52.27627  ? 126 THR E CA  1 
ATOM   5921 C  C   . THR E 1 146 ? -24.47489 -6.65103  61.54787  1.000 45.87488  ? 126 THR E C   1 
ATOM   5922 O  O   . THR E 1 146 ? -25.33742 -6.11727  60.84043  1.000 50.13334  ? 126 THR E O   1 
ATOM   5923 C  CB  . THR E 1 146 ? -22.15032 -6.85065  60.62073  1.000 42.84589  ? 126 THR E CB  1 
ATOM   5924 O  OG1 . THR E 1 146 ? -20.80838 -6.36468  60.73836  1.000 45.79780  ? 126 THR E OG1 1 
ATOM   5925 C  CG2 . THR E 1 146 ? -22.62019 -6.66491  59.18584  1.000 37.31464  ? 126 THR E CG2 1 
ATOM   5926 N  N   . ALA E 1 147 ? -24.73763 -7.72210  62.29947  1.000 42.83102  ? 127 ALA E N   1 
ATOM   5927 C  CA  . ALA E 1 147 ? -26.08290 -8.28359  62.32720  1.000 52.65331  ? 127 ALA E CA  1 
ATOM   5928 C  C   . ALA E 1 147 ? -27.05531 -7.34507  63.03009  1.000 55.57541  ? 127 ALA E C   1 
ATOM   5929 O  O   . ALA E 1 147 ? -28.22193 -7.24056  62.63336  1.000 55.77241  ? 127 ALA E O   1 
ATOM   5930 C  CB  . ALA E 1 147 ? -26.06708 -9.65475  63.00188  1.000 37.44079  ? 127 ALA E CB  1 
ATOM   5931 N  N   . ALA E 1 148 ? -26.59555 -6.65067  64.07401  1.000 48.21747  ? 128 ALA E N   1 
ATOM   5932 C  CA  . ALA E 1 148 ? -27.47259 -5.70552  64.75911  1.000 56.35297  ? 128 ALA E CA  1 
ATOM   5933 C  C   . ALA E 1 148 ? -27.73586 -4.46914  63.90508  1.000 63.44111  ? 128 ALA E C   1 
ATOM   5934 O  O   . ALA E 1 148 ? -28.88069 -4.01455  63.79829  1.000 60.98344  ? 128 ALA E O   1 
ATOM   5935 C  CB  . ALA E 1 148 ? -26.87196 -5.31240  66.10836  1.000 55.08034  ? 128 ALA E CB  1 
ATOM   5936 N  N   . GLN E 1 149 ? -26.69026 -3.91498  63.28599  1.000 58.07404  ? 129 GLN E N   1 
ATOM   5937 C  CA  . GLN E 1 149 ? -26.83703 -2.72344  62.45729  1.000 64.15609  ? 129 GLN E CA  1 
ATOM   5938 C  C   . GLN E 1 149 ? -27.67501 -2.97925  61.21203  1.000 62.12062  ? 129 GLN E C   1 
ATOM   5939 O  O   . GLN E 1 149 ? -28.17005 -2.02161  60.60829  1.000 67.77180  ? 129 GLN E O   1 
ATOM   5940 C  CB  . GLN E 1 149 ? -25.46144 -2.18334  62.06031  1.000 60.51060  ? 129 GLN E CB  1 
ATOM   5941 C  CG  . GLN E 1 149 ? -24.65499 -1.62720  63.23534  1.000 75.75034  ? 129 GLN E CG  1 
ATOM   5942 C  CD  . GLN E 1 149 ? -23.26159 -1.17991  62.82869  1.000 73.64556  ? 129 GLN E CD  1 
ATOM   5943 O  OE1 . GLN E 1 149 ? -22.76500 -1.55112  61.76745  1.000 75.47152  ? 129 GLN E OE1 1 
ATOM   5944 N  NE2 . GLN E 1 149 ? -22.62453 -0.37207  63.67594  1.000 67.31903  ? 129 GLN E NE2 1 
ATOM   5945 N  N   . ALA E 1 150 ? -27.82986 -4.23788  60.80611  1.000 55.51420  ? 130 ALA E N   1 
ATOM   5946 C  CA  . ALA E 1 150 ? -28.73919 -4.60244  59.72983  1.000 58.11224  ? 130 ALA E CA  1 
ATOM   5947 C  C   . ALA E 1 150 ? -30.18119 -4.72736  60.20549  1.000 66.26749  ? 130 ALA E C   1 
ATOM   5948 O  O   . ALA E 1 150 ? -31.03379 -5.19651  59.44288  1.000 68.47717  ? 130 ALA E O   1 
ATOM   5949 C  CB  . ALA E 1 150 ? -28.28782 -5.91299  59.07918  1.000 55.64231  ? 130 ALA E CB  1 
ATOM   5950 N  N   . GLY E 1 151 ? -30.46520 -4.31670  61.44104  1.000 66.72665  ? 131 GLY E N   1 
ATOM   5951 C  CA  . GLY E 1 151 ? -31.78996 -4.42919  62.01035  1.000 72.03840  ? 131 GLY E CA  1 
ATOM   5952 C  C   . GLY E 1 151 ? -32.14838 -5.80145  62.52924  1.000 76.13068  ? 131 GLY E C   1 
ATOM   5953 O  O   . GLY E 1 151 ? -33.33133 -6.06266  62.77081  1.000 74.76765  ? 131 GLY E O   1 
ATOM   5954 N  N   . GLY E 1 152 ? -31.17164 -6.68836  62.70688  1.000 63.98371  ? 132 GLY E N   1 
ATOM   5955 C  CA  . GLY E 1 152 ? -31.46773 -8.03460  63.16277  1.000 57.51084  ? 132 GLY E CA  1 
ATOM   5956 C  C   . GLY E 1 152 ? -31.68271 -8.08910  64.66703  1.000 64.77214  ? 132 GLY E C   1 
ATOM   5957 O  O   . GLY E 1 152 ? -30.99498 -7.42720  65.44289  1.000 66.66439  ? 132 GLY E O   1 
ATOM   5958 N  N   . ASP E 1 153 ? -32.65459 -8.90227  65.07322  1.000 59.41864  ? 133 ASP E N   1 
ATOM   5959 C  CA  . ASP E 1 153 ? -32.95732 -9.11414  66.48309  1.000 67.55122  ? 133 ASP E CA  1 
ATOM   5960 C  C   . ASP E 1 153 ? -32.29142 -10.36027 67.04986  1.000 65.30417  ? 133 ASP E C   1 
ATOM   5961 O  O   . ASP E 1 153 ? -32.28205 -10.53677 68.27363  1.000 67.08813  ? 133 ASP E O   1 
ATOM   5962 C  CB  . ASP E 1 153 ? -34.46952 -9.19249  66.69877  1.000 65.70108  ? 133 ASP E CB  1 
ATOM   5963 C  CG  . ASP E 1 153 ? -35.12678 -10.25937 65.84040  1.000 68.29590  ? 133 ASP E CG  1 
ATOM   5964 O  OD1 . ASP E 1 153 ? -34.54607 -10.62058 64.79635  1.000 72.44820  ? 133 ASP E OD1 1 
ATOM   5965 O  OD2 . ASP E 1 153 ? -36.22311 -10.73442 66.20443  1.000 76.32926  ? 133 ASP E OD2 1 
ATOM   5966 N  N   . ALA E 1 154 ? -31.74055 -11.22207 66.19725  1.000 61.55260  ? 134 ALA E N   1 
ATOM   5967 C  CA  . ALA E 1 154 ? -31.08930 -12.43888 66.65352  1.000 63.09707  ? 134 ALA E CA  1 
ATOM   5968 C  C   . ALA E 1 154 ? -30.01899 -12.85021 65.65252  1.000 62.88864  ? 134 ALA E C   1 
ATOM   5969 O  O   . ALA E 1 154 ? -30.13146 -12.58491 64.45234  1.000 57.29133  ? 134 ALA E O   1 
ATOM   5970 C  CB  . ALA E 1 154 ? -32.09764 -13.57624 66.84673  1.000 49.44800  ? 134 ALA E CB  1 
ATOM   5971 N  N   . LEU E 1 155 ? -28.97459 -13.49705 66.16626  1.000 56.66226  ? 135 LEU E N   1 
ATOM   5972 C  CA  . LEU E 1 155 ? -27.91531 -14.08713 65.35811  1.000 47.44358  ? 135 LEU E CA  1 
ATOM   5973 C  C   . LEU E 1 155 ? -27.85400 -15.57247 65.67634  1.000 48.93862  ? 135 LEU E C   1 
ATOM   5974 O  O   . LEU E 1 155 ? -27.61506 -15.95762 66.82791  1.000 44.12007  ? 135 LEU E O   1 
ATOM   5975 C  CB  . LEU E 1 155 ? -26.56523 -13.41563 65.61972  1.000 51.38386  ? 135 LEU E CB  1 
ATOM   5976 C  CG  . LEU E 1 155 ? -25.40225 -13.91112 64.75326  1.000 49.11745  ? 135 LEU E CG  1 
ATOM   5977 C  CD1 . LEU E 1 155 ? -25.75125 -13.80100 63.27509  1.000 37.06320  ? 135 LEU E CD1 1 
ATOM   5978 C  CD2 . LEU E 1 155 ? -24.12061 -13.14814 65.06118  1.000 38.63380  ? 135 LEU E CD2 1 
ATOM   5979 N  N   . ARG E 1 156 ? -28.08754 -16.39642 64.66062  1.000 52.59050  ? 136 ARG E N   1 
ATOM   5980 C  CA  . ARG E 1 156 ? -28.09461 -17.84379 64.78923  1.000 52.01858  ? 136 ARG E CA  1 
ATOM   5981 C  C   . ARG E 1 156 ? -26.85465 -18.42459 64.12569  1.000 55.30753  ? 136 ARG E C   1 
ATOM   5982 O  O   . ARG E 1 156 ? -26.36730 -17.90465 63.11823  1.000 53.07484  ? 136 ARG E O   1 
ATOM   5983 C  CB  . ARG E 1 156 ? -29.35533 -18.44003 64.15678  1.000 62.16021  ? 136 ARG E CB  1 
ATOM   5984 C  CG  . ARG E 1 156 ? -30.64465 -17.93855 64.78250  1.000 59.86777  ? 136 ARG E CG  1 
ATOM   5985 C  CD  . ARG E 1 156 ? -31.85796 -18.32678 63.95608  1.000 63.49275  ? 136 ARG E CD  1 
ATOM   5986 N  NE  . ARG E 1 156 ? -33.10051 -17.96350 64.62682  1.000 74.50147  ? 136 ARG E NE  1 
ATOM   5987 C  CZ  . ARG E 1 156 ? -34.30322 -18.05439 64.07725  1.000 67.82823  ? 136 ARG E CZ  1 
ATOM   5988 N  NH1 . ARG E 1 156 ? -34.46444 -18.47747 62.83445  1.000 70.17067  ? 136 ARG E NH1 1 
ATOM   5989 N  NH2 . ARG E 1 156 ? -35.37056 -17.71035 64.79201  1.000 71.57327  ? 136 ARG E NH2 1 
ATOM   5990 N  N   . SER E 1 157 ? -26.34386 -19.50897 64.69885  1.000 49.49806  ? 137 SER E N   1 
ATOM   5991 C  CA  . SER E 1 157 ? -25.12571 -20.10609 64.17671  1.000 44.11957  ? 137 SER E CA  1 
ATOM   5992 C  C   . SER E 1 157 ? -25.14319 -21.60120 64.44643  1.000 47.88773  ? 137 SER E C   1 
ATOM   5993 O  O   . SER E 1 157 ? -25.84886 -22.07920 65.33694  1.000 45.88799  ? 137 SER E O   1 
ATOM   5994 C  CB  . SER E 1 157 ? -23.87699 -19.46323 64.79540  1.000 53.05407  ? 137 SER E CB  1 
ATOM   5995 O  OG  . SER E 1 157 ? -22.69708 -19.88457 64.13154  1.000 51.02470  ? 137 SER E OG  1 
ATOM   5996 N  N   . GLU E 1 158 ? -24.37422 -22.33649 63.65339  1.000 56.26194  ? 138 GLU E N   1 
ATOM   5997 C  CA  . GLU E 1 158 ? -24.14622 -23.75533 63.87991  1.000 56.87964  ? 138 GLU E CA  1 
ATOM   5998 C  C   . GLU E 1 158 ? -22.67004 -23.93546 64.20156  1.000 48.66022  ? 138 GLU E C   1 
ATOM   5999 O  O   . GLU E 1 158 ? -21.80630 -23.53207 63.41486  1.000 58.02654  ? 138 GLU E O   1 
ATOM   6000 C  CB  . GLU E 1 158 ? -24.55842 -24.59032 62.66563  1.000 48.99360  ? 138 GLU E CB  1 
ATOM   6001 C  CG  . GLU E 1 158 ? -24.45204 -26.08419 62.89696  1.000 54.49000  ? 138 GLU E CG  1 
ATOM   6002 C  CD  . GLU E 1 158 ? -24.83483 -26.90223 61.68172  1.000 70.29595  ? 138 GLU E CD  1 
ATOM   6003 O  OE1 . GLU E 1 158 ? -26.00478 -26.82372 61.24906  1.000 63.21349  ? 138 GLU E OE1 1 
ATOM   6004 O  OE2 . GLU E 1 158 ? -23.96166 -27.62829 61.15825  1.000 74.38209  ? 138 GLU E OE2 1 
ATOM   6005 N  N   . ALA E 1 159 ? -22.38262 -24.52683 65.35736  1.000 54.03113  ? 139 ALA E N   1 
ATOM   6006 C  CA  . ALA E 1 159 ? -21.01831 -24.61488 65.85362  1.000 51.66821  ? 139 ALA E CA  1 
ATOM   6007 C  C   . ALA E 1 159 ? -20.64705 -26.06552 66.11752  1.000 51.31161  ? 139 ALA E C   1 
ATOM   6008 O  O   . ALA E 1 159 ? -21.50745 -26.92715 66.30959  1.000 53.36480  ? 139 ALA E O   1 
ATOM   6009 C  CB  . ALA E 1 159 ? -20.83270 -23.78764 67.13323  1.000 42.00889  ? 139 ALA E CB  1 
ATOM   6010 N  N   . ASN E 1 160 ? -19.34183 -26.32480 66.11986  1.000 54.02940  ? 140 ASN E N   1 
ATOM   6011 C  CA  . ASN E 1 160 ? -18.82749 -27.63575 66.47688  1.000 56.09725  ? 140 ASN E CA  1 
ATOM   6012 C  C   . ASN E 1 160 ? -18.33823 -27.57935 67.91360  1.000 55.14144  ? 140 ASN E C   1 
ATOM   6013 O  O   . ASN E 1 160 ? -17.31054 -26.93763 68.18147  1.000 51.26511  ? 140 ASN E O   1 
ATOM   6014 C  CB  . ASN E 1 160 ? -17.69677 -28.05408 65.53827  1.000 58.36819  ? 140 ASN E CB  1 
ATOM   6015 C  CG  . ASN E 1 160 ? -17.17291 -29.44848 65.83784  1.000 64.86407  ? 140 ASN E CG  1 
ATOM   6016 O  OD1 . ASN E 1 160 ? -15.96690 -29.65535 65.98215  1.000 67.17708  ? 140 ASN E OD1 1 
ATOM   6017 N  ND2 . ASN E 1 160 ? -18.08160 -30.41142 65.94222  1.000 63.54972  ? 140 ASN E ND2 1 
ATOM   6018 N  N   . PRO E 1 161 ? -19.02677 -28.21504 68.86472  1.000 66.95420  ? 141 PRO E N   1 
ATOM   6019 C  CA  . PRO E 1 161 ? -18.59970 -28.11313 70.26956  1.000 64.19708  ? 141 PRO E CA  1 
ATOM   6020 C  C   . PRO E 1 161 ? -17.24161 -28.73457 70.53694  1.000 62.22674  ? 141 PRO E C   1 
ATOM   6021 O  O   . PRO E 1 161 ? -16.63628 -28.43835 71.57523  1.000 55.83655  ? 141 PRO E O   1 
ATOM   6022 C  CB  . PRO E 1 161 ? -19.71361 -28.84624 71.02970  1.000 54.76740  ? 141 PRO E CB  1 
ATOM   6023 C  CG  . PRO E 1 161 ? -20.29729 -29.78555 70.02525  1.000 62.16291  ? 141 PRO E CG  1 
ATOM   6024 C  CD  . PRO E 1 161 ? -20.21329 -29.07298 68.70374  1.000 58.95184  ? 141 PRO E CD  1 
ATOM   6025 N  N   . ASP E 1 162 ? -16.74005 -29.58245 69.63662  1.000 54.74835  ? 142 ASP E N   1 
ATOM   6026 C  CA  . ASP E 1 162 ? -15.41145 -30.16186 69.78774  1.000 59.30817  ? 142 ASP E CA  1 
ATOM   6027 C  C   . ASP E 1 162 ? -14.29496 -29.18079 69.45094  1.000 60.52386  ? 142 ASP E C   1 
ATOM   6028 O  O   . ASP E 1 162 ? -13.13232 -29.46533 69.75783  1.000 66.53572  ? 142 ASP E O   1 
ATOM   6029 C  CB  . ASP E 1 162 ? -15.28814 -31.41682 68.91894  1.000 73.38914  ? 142 ASP E CB  1 
ATOM   6030 C  CG  . ASP E 1 162 ? -16.19027 -32.54142 69.39421  1.000 66.67431  ? 142 ASP E CG  1 
ATOM   6031 O  OD1 . ASP E 1 162 ? -16.30778 -32.73077 70.62263  1.000 65.17590  ? 142 ASP E OD1 1 
ATOM   6032 O  OD2 . ASP E 1 162 ? -16.78890 -33.23081 68.54170  1.000 68.27954  ? 142 ASP E OD2 1 
ATOM   6033 N  N   . LEU E 1 163 ? -14.61323 -28.04464 68.82785  1.000 61.40481  ? 143 LEU E N   1 
ATOM   6034 C  CA  . LEU E 1 163 ? -13.66229 -26.94310 68.67136  1.000 58.16905  ? 143 LEU E CA  1 
ATOM   6035 C  C   . LEU E 1 163 ? -13.75829 -26.10174 69.93792  1.000 56.21186  ? 143 LEU E C   1 
ATOM   6036 O  O   . LEU E 1 163 ? -14.52564 -25.14124 70.01758  1.000 58.87922  ? 143 LEU E O   1 
ATOM   6037 C  CB  . LEU E 1 163 ? -13.96420 -26.13210 67.41653  1.000 57.66104  ? 143 LEU E CB  1 
ATOM   6038 C  CG  . LEU E 1 163 ? -13.91401 -26.85645 66.06514  1.000 59.93044  ? 143 LEU E CG  1 
ATOM   6039 C  CD1 . LEU E 1 163 ? -14.18754 -25.89572 64.91560  1.000 40.81870  ? 143 LEU E CD1 1 
ATOM   6040 C  CD2 . LEU E 1 163 ? -12.57922 -27.55338 65.86443  1.000 52.33669  ? 143 LEU E CD2 1 
ATOM   6041 N  N   . SER E 1 164 ? -12.95747 -26.47086 70.94170  1.000 58.73800  ? 144 SER E N   1 
ATOM   6042 C  CA  . SER E 1 164 ? -13.17060 -25.96859 72.29740  1.000 59.70775  ? 144 SER E CA  1 
ATOM   6043 C  C   . SER E 1 164 ? -12.94627 -24.46338 72.39686  1.000 55.86235  ? 144 SER E C   1 
ATOM   6044 O  O   . SER E 1 164 ? -13.73881 -23.75764 73.03206  1.000 56.10280  ? 144 SER E O   1 
ATOM   6045 C  CB  . SER E 1 164 ? -12.26282 -26.71265 73.27462  1.000 58.62897  ? 144 SER E CB  1 
ATOM   6046 O  OG  . SER E 1 164 ? -12.56914 -28.09611 73.29093  1.000 68.93498  ? 144 SER E OG  1 
ATOM   6047 N  N   . ALA E 1 165 ? -11.87359 -23.95268 71.78816  1.000 56.35689  ? 145 ALA E N   1 
ATOM   6048 C  CA  . ALA E 1 165 ? -11.58732 -22.52251 71.87347  1.000 46.16129  ? 145 ALA E CA  1 
ATOM   6049 C  C   . ALA E 1 165 ? -12.71787 -21.69845 71.26938  1.000 57.83572  ? 145 ALA E C   1 
ATOM   6050 O  O   . ALA E 1 165 ? -13.20285 -20.73975 71.88359  1.000 51.73635  ? 145 ALA E O   1 
ATOM   6051 C  CB  . ALA E 1 165 ? -10.26232 -22.21025 71.17983  1.000 47.83677  ? 145 ALA E CB  1 
ATOM   6052 N  N   . THR E 1 166 ? -13.16011 -22.06857 70.06525  1.000 55.39342  ? 146 THR E N   1 
ATOM   6053 C  CA  . THR E 1 166 ? -14.25536 -21.34807 69.42491  1.000 51.13828  ? 146 THR E CA  1 
ATOM   6054 C  C   . THR E 1 166 ? -15.55564 -21.51931 70.20072  1.000 44.87728  ? 146 THR E C   1 
ATOM   6055 O  O   . THR E 1 166 ? -16.35083 -20.57803 70.30561  1.000 48.53257  ? 146 THR E O   1 
ATOM   6056 C  CB  . THR E 1 166 ? -14.41966 -21.82500 67.98119  1.000 45.24200  ? 146 THR E CB  1 
ATOM   6057 O  OG1 . THR E 1 166 ? -13.17210 -21.68819 67.28994  1.000 49.06238  ? 146 THR E OG1 1 
ATOM   6058 C  CG2 . THR E 1 166 ? -15.47946 -21.00853 67.26173  1.000 40.72931  ? 146 THR E CG2 1 
ATOM   6059 N  N   . ARG E 1 167 ? -15.78761 -22.71240 70.75230  1.000 47.22655  ? 147 ARG E N   1 
ATOM   6060 C  CA  . ARG E 1 167 ? -17.00166 -22.94986 71.52659  1.000 51.11855  ? 147 ARG E CA  1 
ATOM   6061 C  C   . ARG E 1 167 ? -17.05786 -22.03405 72.74325  1.000 50.78312  ? 147 ARG E C   1 
ATOM   6062 O  O   . ARG E 1 167 ? -18.09208 -21.41773 73.02904  1.000 51.12601  ? 147 ARG E O   1 
ATOM   6063 C  CB  . ARG E 1 167 ? -17.07202 -24.42004 71.94708  1.000 49.20363  ? 147 ARG E CB  1 
ATOM   6064 C  CG  . ARG E 1 167 ? -18.35661 -24.79982 72.66667  1.000 46.06345  ? 147 ARG E CG  1 
ATOM   6065 C  CD  . ARG E 1 167 ? -19.56852 -24.57505 71.77916  1.000 48.15014  ? 147 ARG E CD  1 
ATOM   6066 N  NE  . ARG E 1 167 ? -20.81634 -24.72583 72.51696  1.000 50.93222  ? 147 ARG E NE  1 
ATOM   6067 C  CZ  . ARG E 1 167 ? -21.42363 -23.74177 73.16623  1.000 59.93986  ? 147 ARG E CZ  1 
ATOM   6068 N  NH1 . ARG E 1 167 ? -20.92174 -22.51724 73.19341  1.000 52.29423  ? 147 ARG E NH1 1 
ATOM   6069 N  NH2 . ARG E 1 167 ? -22.56259 -23.99199 73.80524  1.000 52.72649  ? 147 ARG E NH2 1 
ATOM   6070 N  N   . SER E 1 168 ? -15.94074 -21.92005 73.46432  1.000 49.79376  ? 148 SER E N   1 
ATOM   6071 C  CA  . SER E 1 168 ? -15.89669 -21.03739 74.62398  1.000 53.69185  ? 148 SER E CA  1 
ATOM   6072 C  C   . SER E 1 168 ? -16.00226 -19.57374 74.21338  1.000 54.84026  ? 148 SER E C   1 
ATOM   6073 O  O   . SER E 1 168 ? -16.65773 -18.78247 74.90016  1.000 51.37708  ? 148 SER E O   1 
ATOM   6074 C  CB  . SER E 1 168 ? -14.62135 -21.28761 75.42707  1.000 52.65947  ? 148 SER E CB  1 
ATOM   6075 O  OG  . SER E 1 168 ? -14.73448 -22.48009 76.18386  1.000 63.71086  ? 148 SER E OG  1 
ATOM   6076 N  N   . LEU E 1 169 ? -15.36858 -19.19179 73.09917  1.000 51.79890  ? 149 LEU E N   1 
ATOM   6077 C  CA  . LEU E 1 169 ? -15.49482 -17.81740 72.62105  1.000 48.32260  ? 149 LEU E CA  1 
ATOM   6078 C  C   . LEU E 1 169 ? -16.94733 -17.47250 72.31928  1.000 50.15945  ? 149 LEU E C   1 
ATOM   6079 O  O   . LEU E 1 169 ? -17.41323 -16.37239 72.63904  1.000 55.62816  ? 149 LEU E O   1 
ATOM   6080 C  CB  . LEU E 1 169 ? -14.62821 -17.60669 71.38009  1.000 43.98003  ? 149 LEU E CB  1 
ATOM   6081 C  CG  . LEU E 1 169 ? -14.74003 -16.22924 70.72172  1.000 47.56854  ? 149 LEU E CG  1 
ATOM   6082 C  CD1 . LEU E 1 169 ? -14.35015 -15.13777 71.70624  1.000 52.72107  ? 149 LEU E CD1 1 
ATOM   6083 C  CD2 . LEU E 1 169 ? -13.88580 -16.15053 69.46484  1.000 47.26569  ? 149 LEU E CD2 1 
ATOM   6084 N  N   . LEU E 1 170 ? -17.67915 -18.40417 71.70565  1.000 47.36718  ? 150 LEU E N   1 
ATOM   6085 C  CA  . LEU E 1 170 ? -19.09852 -18.18239 71.45059  1.000 47.58673  ? 150 LEU E CA  1 
ATOM   6086 C  C   . LEU E 1 170 ? -19.89262 -18.14145 72.75143  1.000 51.49314  ? 150 LEU E C   1 
ATOM   6087 O  O   . LEU E 1 170 ? -20.83423 -17.35183 72.88661  1.000 40.94232  ? 150 LEU E O   1 
ATOM   6088 C  CB  . LEU E 1 170 ? -19.63845 -19.27018 70.52100  1.000 42.37736  ? 150 LEU E CB  1 
ATOM   6089 C  CG  . LEU E 1 170 ? -19.09376 -19.27281 69.08945  1.000 47.09668  ? 150 LEU E CG  1 
ATOM   6090 C  CD1 . LEU E 1 170 ? -19.24538 -20.64550 68.45167  1.000 33.24991  ? 150 LEU E CD1 1 
ATOM   6091 C  CD2 . LEU E 1 170 ? -19.79021 -18.21498 68.24729  1.000 34.22268  ? 150 LEU E CD2 1 
ATOM   6092 N  N   . ASP E 1 171 ? -19.52473 -18.97890 73.72282  1.000 51.57861  ? 151 ASP E N   1 
ATOM   6093 C  CA  . ASP E 1 171 ? -20.25990 -19.00655 74.98333  1.000 52.24263  ? 151 ASP E CA  1 
ATOM   6094 C  C   . ASP E 1 171 ? -20.08813 -17.70516 75.76004  1.000 47.05105  ? 151 ASP E C   1 
ATOM   6095 O  O   . ASP E 1 171 ? -21.04489 -17.20612 76.36362  1.000 44.51928  ? 151 ASP E O   1 
ATOM   6096 C  CB  . ASP E 1 171 ? -19.80931 -20.19943 75.82506  1.000 46.33515  ? 151 ASP E CB  1 
ATOM   6097 C  CG  . ASP E 1 171 ? -20.54197 -20.28661 77.14761  1.000 56.09810  ? 151 ASP E CG  1 
ATOM   6098 O  OD1 . ASP E 1 171 ? -21.76110 -20.56069 77.13705  1.000 59.42330  ? 151 ASP E OD1 1 
ATOM   6099 O  OD2 . ASP E 1 171 ? -19.89994 -20.07928 78.19889  1.000 64.03257  ? 151 ASP E OD2 1 
ATOM   6100 N  N   . ILE E 1 172 ? -18.88155 -17.13547 75.74602  1.000 47.21119  ? 152 ILE E N   1 
ATOM   6101 C  CA  . ILE E 1 172 ? -18.61230 -15.93140 76.52854  1.000 45.91100  ? 152 ILE E CA  1 
ATOM   6102 C  C   . ILE E 1 172 ? -19.39475 -14.74281 75.98109  1.000 48.61853  ? 152 ILE E C   1 
ATOM   6103 O  O   . ILE E 1 172 ? -19.87464 -13.89421 76.74265  1.000 52.35386  ? 152 ILE E O   1 
ATOM   6104 C  CB  . ILE E 1 172 ? -17.09833 -15.64871 76.56015  1.000 40.38891  ? 152 ILE E CB  1 
ATOM   6105 C  CG1 . ILE E 1 172 ? -16.35443 -16.79261 77.25049  1.000 48.47978  ? 152 ILE E CG1 1 
ATOM   6106 C  CG2 . ILE E 1 172 ? -16.80634 -14.33994 77.27804  1.000 44.62902  ? 152 ILE E CG2 1 
ATOM   6107 C  CD1 . ILE E 1 172 ? -14.84958 -16.71036 77.10843  1.000 47.34179  ? 152 ILE E CD1 1 
ATOM   6108 N  N   . LEU E 1 173 ? -19.54530 -14.66507 74.66008  1.000 49.15770  ? 153 LEU E N   1 
ATOM   6109 C  CA  . LEU E 1 173 ? -20.19763 -13.52712 74.02328  1.000 48.78671  ? 153 LEU E CA  1 
ATOM   6110 C  C   . LEU E 1 173 ? -21.71967 -13.62766 74.02463  1.000 53.06100  ? 153 LEU E C   1 
ATOM   6111 O  O   . LEU E 1 173 ? -22.38056 -12.76145 73.44204  1.000 49.88639  ? 153 LEU E O   1 
ATOM   6112 C  CB  . LEU E 1 173 ? -19.67427 -13.34844 72.59670  1.000 43.32731  ? 153 LEU E CB  1 
ATOM   6113 C  CG  . LEU E 1 173 ? -18.49503 -12.37832 72.44289  1.000 49.99312  ? 153 LEU E CG  1 
ATOM   6114 C  CD1 . LEU E 1 173 ? -17.31037 -12.77153 73.32321  1.000 49.21130  ? 153 LEU E CD1 1 
ATOM   6115 C  CD2 . LEU E 1 173 ? -18.06309 -12.26610 70.98847  1.000 49.96337  ? 153 LEU E CD2 1 
ATOM   6116 N  N   . GLY E 1 174 ? -22.28794 -14.65155 74.65519  1.000 49.84820  ? 154 GLY E N   1 
ATOM   6117 C  CA  . GLY E 1 174 ? -23.72001 -14.73583 74.84316  1.000 46.57094  ? 154 GLY E CA  1 
ATOM   6118 C  C   . GLY E 1 174 ? -24.46346 -15.68618 73.93178  1.000 50.03705  ? 154 GLY E C   1 
ATOM   6119 O  O   . GLY E 1 174 ? -25.69893 -15.65312 73.91637  1.000 50.68149  ? 154 GLY E O   1 
ATOM   6120 N  N   . PHE E 1 175 ? -23.76349 -16.52522 73.17211  1.000 52.31669  ? 155 PHE E N   1 
ATOM   6121 C  CA  . PHE E 1 175 ? -24.42564 -17.51266 72.32819  1.000 53.57359  ? 155 PHE E CA  1 
ATOM   6122 C  C   . PHE E 1 175 ? -24.92669 -18.66232 73.19461  1.000 59.08459  ? 155 PHE E C   1 
ATOM   6123 O  O   . PHE E 1 175 ? -24.13171 -19.36254 73.83096  1.000 61.45706  ? 155 PHE E O   1 
ATOM   6124 C  CB  . PHE E 1 175 ? -23.47773 -18.01734 71.24093  1.000 53.39701  ? 155 PHE E CB  1 
ATOM   6125 C  CG  . PHE E 1 175 ? -23.28714 -17.04772 70.10547  1.000 46.91758  ? 155 PHE E CG  1 
ATOM   6126 C  CD1 . PHE E 1 175 ? -22.34860 -16.03145 70.19158  1.000 43.27775  ? 155 PHE E CD1 1 
ATOM   6127 C  CD2 . PHE E 1 175 ? -24.05005 -17.15219 68.95267  1.000 41.65223  ? 155 PHE E CD2 1 
ATOM   6128 C  CE1 . PHE E 1 175 ? -22.17501 -15.13842 69.15031  1.000 38.79813  ? 155 PHE E CE1 1 
ATOM   6129 C  CE2 . PHE E 1 175 ? -23.88097 -16.26200 67.90702  1.000 47.10707  ? 155 PHE E CE2 1 
ATOM   6130 C  CZ  . PHE E 1 175 ? -22.94245 -15.25336 68.00680  1.000 41.51580  ? 155 PHE E CZ  1 
ATOM   6131 N  N   . VAL E 1 176 ? -26.24290 -18.85060 73.22241  1.000 51.11095  ? 156 VAL E N   1 
ATOM   6132 C  CA  . VAL E 1 176 ? -26.88310 -19.87891 74.03390  1.000 54.17306  ? 156 VAL E CA  1 
ATOM   6133 C  C   . VAL E 1 176 ? -27.29606 -21.02938 73.12713  1.000 59.53892  ? 156 VAL E C   1 
ATOM   6134 O  O   . VAL E 1 176 ? -27.86575 -20.80976 72.04994  1.000 56.01532  ? 156 VAL E O   1 
ATOM   6135 C  CB  . VAL E 1 176 ? -28.09456 -19.30897 74.79362  1.000 64.29031  ? 156 VAL E CB  1 
ATOM   6136 C  CG1 . VAL E 1 176 ? -28.87645 -20.41912 75.48240  1.000 56.69098  ? 156 VAL E CG1 1 
ATOM   6137 C  CG2 . VAL E 1 176 ? -27.64198 -18.26388 75.80673  1.000 55.87601  ? 156 VAL E CG2 1 
ATOM   6138 N  N   . GLN E 1 177 ? -27.00340 -22.25537 73.55521  1.000 59.78362  ? 157 GLN E N   1 
ATOM   6139 C  CA  . GLN E 1 177 ? -27.41786 -23.43580 72.80956  1.000 57.62554  ? 157 GLN E CA  1 
ATOM   6140 C  C   . GLN E 1 177 ? -28.87656 -23.75789 73.10491  1.000 63.25580  ? 157 GLN E C   1 
ATOM   6141 O  O   . GLN E 1 177 ? -29.28293 -23.82967 74.26923  1.000 65.13772  ? 157 GLN E O   1 
ATOM   6142 C  CB  . GLN E 1 177 ? -26.54052 -24.63670 73.16019  1.000 51.26724  ? 157 GLN E CB  1 
ATOM   6143 C  CG  . GLN E 1 177 ? -26.93200 -25.89918 72.40877  1.000 59.13316  ? 157 GLN E CG  1 
ATOM   6144 C  CD  . GLN E 1 177 ? -26.17304 -27.12377 72.87429  1.000 58.54248  ? 157 GLN E CD  1 
ATOM   6145 O  OE1 . GLN E 1 177 ? -25.10947 -27.01665 73.48463  1.000 50.41922  ? 157 GLN E OE1 1 
ATOM   6146 N  NE2 . GLN E 1 177 ? -26.72203 -28.30000 72.59175  1.000 71.53153  ? 157 GLN E NE2 1 
ATOM   6147 N  N   . HIS E 1 178 ? -29.66042 -23.95264 72.04818  1.000 70.71122  ? 158 HIS E N   1 
ATOM   6148 C  CA  . HIS E 1 178 ? -31.06520 -24.34012 72.15367  1.000 71.05621  ? 158 HIS E CA  1 
ATOM   6149 C  C   . HIS E 1 178 ? -31.24202 -25.66327 71.41646  1.000 76.89524  ? 158 HIS E C   1 
ATOM   6150 O  O   . HIS E 1 178 ? -31.36537 -25.68709 70.18785  1.000 81.25600  ? 158 HIS E O   1 
ATOM   6151 C  CB  . HIS E 1 178 ? -31.98100 -23.25741 71.58967  1.000 76.08073  ? 158 HIS E CB  1 
ATOM   6152 C  CG  . HIS E 1 178 ? -32.07956 -22.03969 72.45457  1.000 84.63160  ? 158 HIS E CG  1 
ATOM   6153 N  ND1 . HIS E 1 178 ? -32.96809 -21.94315 73.50386  1.000 76.88086  ? 158 HIS E ND1 1 
ATOM   6154 C  CD2 . HIS E 1 178 ? -31.40039 -20.86851 72.42775  1.000 78.11933  ? 158 HIS E CD2 1 
ATOM   6155 C  CE1 . HIS E 1 178 ? -32.83264 -20.76496 74.08576  1.000 74.91053  ? 158 HIS E CE1 1 
ATOM   6156 N  NE2 . HIS E 1 178 ? -31.88799 -20.09353 73.45200  1.000 74.16739  ? 158 HIS E NE2 1 
ATOM   6157 N  N   . GLY E 1 179 ? -31.24955 -26.76132 72.16712  1.000 78.57391  ? 159 GLY E N   1 
ATOM   6158 C  CA  . GLY E 1 179 ? -31.41314 -28.07469 71.59420  1.000 68.18691  ? 159 GLY E CA  1 
ATOM   6159 C  C   . GLY E 1 179 ? -30.26459 -28.99968 71.93699  1.000 80.13532  ? 159 GLY E C   1 
ATOM   6160 O  O   . GLY E 1 179 ? -29.23374 -28.58018 72.47338  1.000 69.55827  ? 159 GLY E O   1 
ATOM   6161 N  N   . PRO E 1 180 ? -30.42556 -30.28331 71.63611  1.000 86.21170  ? 160 PRO E N   1 
ATOM   6162 C  CA  . PRO E 1 180 ? -29.36702 -31.25615 71.91780  1.000 84.44394  ? 160 PRO E CA  1 
ATOM   6163 C  C   . PRO E 1 180 ? -28.23281 -31.15680 70.90514  1.000 83.50829  ? 160 PRO E C   1 
ATOM   6164 O  O   . PRO E 1 180 ? -28.31673 -30.46338 69.89117  1.000 77.02828  ? 160 PRO E O   1 
ATOM   6165 C  CB  . PRO E 1 180 ? -30.09093 -32.60124 71.80359  1.000 72.74242  ? 160 PRO E CB  1 
ATOM   6166 C  CG  . PRO E 1 180 ? -31.18671 -32.33804 70.82438  1.000 78.05862  ? 160 PRO E CG  1 
ATOM   6167 C  CD  . PRO E 1 180 ? -31.63147 -30.92091 71.07716  1.000 76.42734  ? 160 PRO E CD  1 
ATOM   6168 N  N   . THR E 1 181 ? -27.15445 -31.87443 71.20492  1.000 76.51477  ? 161 THR E N   1 
ATOM   6169 C  CA  . THR E 1 181 ? -26.03579 -31.98425 70.28013  1.000 68.89989  ? 161 THR E CA  1 
ATOM   6170 C  C   . THR E 1 181 ? -26.35793 -33.02518 69.21321  1.000 74.53450  ? 161 THR E C   1 
ATOM   6171 O  O   . THR E 1 181 ? -26.78352 -34.13990 69.53232  1.000 81.76471  ? 161 THR E O   1 
ATOM   6172 C  CB  . THR E 1 181 ? -24.76002 -32.36151 71.03201  1.000 74.80336  ? 161 THR E CB  1 
ATOM   6173 O  OG1 . THR E 1 181 ? -24.48568 -31.37398 72.03491  1.000 84.18298  ? 161 THR E OG1 1 
ATOM   6174 C  CG2 . THR E 1 181 ? -23.58290 -32.44364 70.07611  1.000 70.02191  ? 161 THR E CG2 1 
ATOM   6175 N  N   . LEU E 1 182 ? -26.16080 -32.66195 67.94752  1.000 73.84185  ? 162 LEU E N   1 
ATOM   6176 C  CA  . LEU E 1 182 ? -26.52881 -33.51035 66.82171  1.000 66.10583  ? 162 LEU E CA  1 
ATOM   6177 C  C   . LEU E 1 182 ? -25.28606 -34.05294 66.12915  1.000 68.50740  ? 162 LEU E C   1 
ATOM   6178 O  O   . LEU E 1 182 ? -24.27888 -33.35041 65.99854  1.000 73.19749  ? 162 LEU E O   1 
ATOM   6179 C  CB  . LEU E 1 182 ? -27.37665 -32.74177 65.80348  1.000 57.47589  ? 162 LEU E CB  1 
ATOM   6180 C  CG  . LEU E 1 182 ? -28.49490 -31.83570 66.32329  1.000 66.82252  ? 162 LEU E CG  1 
ATOM   6181 C  CD1 . LEU E 1 182 ? -29.37209 -31.36908 65.16683  1.000 53.52574  ? 162 LEU E CD1 1 
ATOM   6182 C  CD2 . LEU E 1 182 ? -29.33049 -32.51664 67.40815  1.000 64.13845  ? 162 LEU E CD2 1 
ATOM   6183 N  N   . SER E 1 183 ? -25.36949 -35.30016 65.67495  1.000 68.46680  ? 163 SER E N   1 
ATOM   6184 C  CA  . SER E 1 183 ? -24.32088 -35.93045 64.88839  1.000 70.28586  ? 163 SER E CA  1 
ATOM   6185 C  C   . SER E 1 183 ? -24.82867 -36.21727 63.48053  1.000 73.38543  ? 163 SER E C   1 
ATOM   6186 O  O   . SER E 1 183 ? -26.01059 -36.50746 63.27606  1.000 69.27245  ? 163 SER E O   1 
ATOM   6187 C  CB  . SER E 1 183 ? -23.83407 -37.22535 65.54586  1.000 73.17288  ? 163 SER E CB  1 
ATOM   6188 O  OG  . SER E 1 183 ? -23.09540 -36.95057 66.72356  1.000 72.43658  ? 163 SER E OG  1 
ATOM   6189 N  N   . ASP E 1 184 ? -23.92144 -36.13275 62.50828  1.000 80.30992  ? 164 ASP E N   1 
ATOM   6190 C  CA  . ASP E 1 184 ? -24.26761 -36.27474 61.09912  1.000 87.43173  ? 164 ASP E CA  1 
ATOM   6191 C  C   . ASP E 1 184 ? -24.13634 -37.70605 60.58872  1.000 92.40465  ? 164 ASP E C   1 
ATOM   6192 O  O   . ASP E 1 184 ? -24.20957 -37.92537 59.37502  1.000 91.18070  ? 164 ASP E O   1 
ATOM   6193 C  CB  . ASP E 1 184 ? -23.40052 -35.34319 60.24504  1.000 82.36133  ? 164 ASP E CB  1 
ATOM   6194 C  CG  . ASP E 1 184 ? -21.94320 -35.77139 60.20498  1.000 79.63813  ? 164 ASP E CG  1 
ATOM   6195 O  OD1 . ASP E 1 184 ? -21.47320 -36.38976 61.18273  1.000 83.60524  ? 164 ASP E OD1 1 
ATOM   6196 O  OD2 . ASP E 1 184 ? -21.26644 -35.48709 59.19340  1.000 77.46129  ? 164 ASP E OD2 1 
ATOM   6197 N  N   . GLY E 1 185 ? -23.94558 -38.67993 61.47742  1.000 90.15094  ? 165 GLY E N   1 
ATOM   6198 C  CA  . GLY E 1 185 ? -23.77859 -40.06191 61.09159  1.000 88.21744  ? 165 GLY E CA  1 
ATOM   6199 C  C   . GLY E 1 185 ? -22.33762 -40.49014 60.89815  1.000 88.61258  ? 165 GLY E C   1 
ATOM   6200 O  O   . GLY E 1 185 ? -22.01789 -41.66715 61.09489  1.000 81.30589  ? 165 GLY E O   1 
ATOM   6201 N  N   . GLN E 1 186 ? -21.46067 -39.56339 60.51524  1.000 82.60469  ? 166 GLN E N   1 
ATOM   6202 C  CA  . GLN E 1 186 ? -20.04416 -39.86898 60.36880  1.000 81.63041  ? 166 GLN E CA  1 
ATOM   6203 C  C   . GLN E 1 186 ? -19.26893 -39.64997 61.66093  1.000 89.17369  ? 166 GLN E C   1 
ATOM   6204 O  O   . GLN E 1 186 ? -18.23009 -40.28822 61.86800  1.000 92.04459  ? 166 GLN E O   1 
ATOM   6205 C  CB  . GLN E 1 186 ? -19.44031 -39.02320 59.24181  1.000 85.07747  ? 166 GLN E CB  1 
ATOM   6206 C  CG  . GLN E 1 186 ? -18.10784 -39.53205 58.70285  1.000 89.20672  ? 166 GLN E CG  1 
ATOM   6207 C  CD  . GLN E 1 186 ? -16.91507 -38.96776 59.45033  1.000 98.10726  ? 166 GLN E CD  1 
ATOM   6208 O  OE1 . GLN E 1 186 ? -17.00474 -37.91409 60.08078  1.000 95.52868  ? 166 GLN E OE1 1 
ATOM   6209 N  NE2 . GLN E 1 186 ? -15.78915 -39.66949 59.38454  1.000 99.66291  ? 166 GLN E NE2 1 
ATOM   6210 N  N   . GLY E 1 187 ? -19.75481 -38.77503 62.53880  1.000 86.68040  ? 167 GLY E N   1 
ATOM   6211 C  CA  . GLY E 1 187 ? -19.09062 -38.52218 63.80239  1.000 88.68451  ? 167 GLY E CA  1 
ATOM   6212 C  C   . GLY E 1 187 ? -19.05480 -37.05715 64.18719  1.000 83.43639  ? 167 GLY E C   1 
ATOM   6213 O  O   . GLY E 1 187 ? -18.88934 -36.72349 65.36479  1.000 80.56927  ? 167 GLY E O   1 
ATOM   6214 N  N   . ARG E 1 188 ? -19.20689 -36.17415 63.20068  1.000 75.34938  ? 168 ARG E N   1 
ATOM   6215 C  CA  . ARG E 1 188 ? -19.17219 -34.74057 63.46134  1.000 81.91744  ? 168 ARG E CA  1 
ATOM   6216 C  C   . ARG E 1 188 ? -20.31695 -34.33011 64.37711  1.000 79.62834  ? 168 ARG E C   1 
ATOM   6217 O  O   . ARG E 1 188 ? -21.47267 -34.70267 64.15598  1.000 75.37154  ? 168 ARG E O   1 
ATOM   6218 C  CB  . ARG E 1 188 ? -19.24843 -33.95563 62.15081  1.000 81.14847  ? 168 ARG E CB  1 
ATOM   6219 C  CG  . ARG E 1 188 ? -17.90550 -33.52467 61.58136  1.000 86.13411  ? 168 ARG E CG  1 
ATOM   6220 C  CD  . ARG E 1 188 ? -17.40967 -34.49844 60.52715  1.000 86.39925  ? 168 ARG E CD  1 
ATOM   6221 N  NE  . ARG E 1 188 ? -16.46964 -33.86640 59.60836  1.000 82.84669  ? 168 ARG E NE  1 
ATOM   6222 C  CZ  . ARG E 1 188 ? -16.02963 -34.42108 58.48693  1.000 81.86649  ? 168 ARG E CZ  1 
ATOM   6223 N  NH1 . ARG E 1 188 ? -16.42052 -35.62848 58.11326  1.000 77.72858  ? 168 ARG E NH1 1 
ATOM   6224 N  NH2 . ARG E 1 188 ? -15.17869 -33.74611 57.71922  1.000 68.38027  ? 168 ARG E NH2 1 
ATOM   6225 N  N   . ARG E 1 189 ? -19.98871 -33.55686 65.40570  1.000 78.30494  ? 169 ARG E N   1 
ATOM   6226 C  CA  . ARG E 1 189 ? -20.97192 -32.99904 66.31950  1.000 71.52655  ? 169 ARG E CA  1 
ATOM   6227 C  C   . ARG E 1 189 ? -21.27721 -31.55483 65.94204  1.000 60.56966  ? 169 ARG E C   1 
ATOM   6228 O  O   . ARG E 1 189 ? -20.41944 -30.83263 65.42790  1.000 61.32642  ? 169 ARG E O   1 
ATOM   6229 C  CB  . ARG E 1 189 ? -20.47049 -33.07314 67.76329  1.000 71.84273  ? 169 ARG E CB  1 
ATOM   6230 C  CG  . ARG E 1 189 ? -20.82718 -34.37112 68.46984  1.000 69.34600  ? 169 ARG E CG  1 
ATOM   6231 C  CD  . ARG E 1 189 ? -19.72883 -34.80987 69.42021  1.000 67.35819  ? 169 ARG E CD  1 
ATOM   6232 N  NE  . ARG E 1 189 ? -19.34329 -33.75721 70.35160  1.000 81.67729  ? 169 ARG E NE  1 
ATOM   6233 C  CZ  . ARG E 1 189 ? -19.95111 -33.51412 71.50429  1.000 81.81776  ? 169 ARG E CZ  1 
ATOM   6234 N  NH1 . ARG E 1 189 ? -21.00761 -34.21033 71.88805  1.000 77.47246  ? 169 ARG E NH1 1 
ATOM   6235 N  NH2 . ARG E 1 189 ? -19.48485 -32.54941 72.29267  1.000 77.89513  ? 169 ARG E NH2 1 
ATOM   6236 N  N   . ARG E 1 190 ? -22.51713 -31.14230 66.19298  1.000 57.53838  ? 170 ARG E N   1 
ATOM   6237 C  CA  . ARG E 1 190 ? -22.93195 -29.77788 65.90735  1.000 63.09951  ? 170 ARG E CA  1 
ATOM   6238 C  C   . ARG E 1 190 ? -24.00708 -29.35595 66.89744  1.000 63.20973  ? 170 ARG E C   1 
ATOM   6239 O  O   . ARG E 1 190 ? -24.83302 -30.16586 67.32859  1.000 60.41565  ? 170 ARG E O   1 
ATOM   6240 C  CB  . ARG E 1 190 ? -23.44659 -29.62536 64.46921  1.000 64.58028  ? 170 ARG E CB  1 
ATOM   6241 C  CG  . ARG E 1 190 ? -24.76295 -30.33143 64.18307  1.000 65.33142  ? 170 ARG E CG  1 
ATOM   6242 C  CD  . ARG E 1 190 ? -25.17195 -30.13382 62.73607  1.000 60.88165  ? 170 ARG E CD  1 
ATOM   6243 N  NE  . ARG E 1 190 ? -26.50787 -30.64357 62.45279  1.000 72.85239  ? 170 ARG E NE  1 
ATOM   6244 C  CZ  . ARG E 1 190 ? -26.76810 -31.87273 62.02714  1.000 75.88900  ? 170 ARG E CZ  1 
ATOM   6245 N  NH1 . ARG E 1 190 ? -25.80329 -32.75973 61.83921  1.000 63.94081  ? 170 ARG E NH1 1 
ATOM   6246 N  NH2 . ARG E 1 190 ? -28.02811 -32.22048 61.78101  1.000 70.26382  ? 170 ARG E NH2 1 
ATOM   6247 N  N   . VAL E 1 191 ? -23.97788 -28.07534 67.25743  1.000 64.37364  ? 171 VAL E N   1 
ATOM   6248 C  CA  . VAL E 1 191 ? -24.97165 -27.46983 68.13040  1.000 59.61633  ? 171 VAL E CA  1 
ATOM   6249 C  C   . VAL E 1 191 ? -25.48383 -26.20569 67.45782  1.000 60.96298  ? 171 VAL E C   1 
ATOM   6250 O  O   . VAL E 1 191 ? -24.78453 -25.57507 66.65665  1.000 63.43807  ? 171 VAL E O   1 
ATOM   6251 C  CB  . VAL E 1 191 ? -24.40537 -27.14802 69.53266  1.000 53.65598  ? 171 VAL E CB  1 
ATOM   6252 C  CG1 . VAL E 1 191 ? -23.99267 -28.42645 70.24978  1.000 47.43201  ? 171 VAL E CG1 1 
ATOM   6253 C  CG2 . VAL E 1 191 ? -23.23100 -26.18221 69.42577  1.000 49.11206  ? 171 VAL E CG2 1 
ATOM   6254 N  N   . HIS E 1 192 ? -26.72012 -25.84067 67.78123  1.000 57.16638  ? 172 HIS E N   1 
ATOM   6255 C  CA  . HIS E 1 192 ? -27.35006 -24.64746 67.23294  1.000 56.65561  ? 172 HIS E CA  1 
ATOM   6256 C  C   . HIS E 1 192 ? -27.37530 -23.57031 68.30934  1.000 52.29546  ? 172 HIS E C   1 
ATOM   6257 O  O   . HIS E 1 192 ? -28.01830 -23.74032 69.35154  1.000 56.24556  ? 172 HIS E O   1 
ATOM   6258 C  CB  . HIS E 1 192 ? -28.75783 -24.95250 66.72158  1.000 56.12503  ? 172 HIS E CB  1 
ATOM   6259 C  CG  . HIS E 1 192 ? -28.77881 -25.80576 65.49016  1.000 65.43283  ? 172 HIS E CG  1 
ATOM   6260 N  ND1 . HIS E 1 192 ? -29.27636 -27.09123 65.48185  1.000 68.38340  ? 172 HIS E ND1 1 
ATOM   6261 C  CD2 . HIS E 1 192 ? -28.35650 -25.55873 64.22698  1.000 71.28311  ? 172 HIS E CD2 1 
ATOM   6262 C  CE1 . HIS E 1 192 ? -29.16345 -27.59781 64.26671  1.000 64.17343  ? 172 HIS E CE1 1 
ATOM   6263 N  NE2 . HIS E 1 192 ? -28.60755 -26.68856 63.48635  1.000 71.29136  ? 172 HIS E NE2 1 
ATOM   6264 N  N   . LEU E 1 193 ? -26.66273 -22.47614 68.05948  1.000 49.03336  ? 173 LEU E N   1 
ATOM   6265 C  CA  . LEU E 1 193 ? -26.49365 -21.39285 69.01175  1.000 48.63050  ? 173 LEU E CA  1 
ATOM   6266 C  C   . LEU E 1 193 ? -27.30863 -20.17925 68.58478  1.000 52.75149  ? 173 LEU E C   1 
ATOM   6267 O  O   . LEU E 1 193 ? -27.45971 -19.89649 67.39053  1.000 51.85760  ? 173 LEU E O   1 
ATOM   6268 C  CB  . LEU E 1 193 ? -25.01838 -21.00520 69.13558  1.000 42.67809  ? 173 LEU E CB  1 
ATOM   6269 C  CG  . LEU E 1 193 ? -24.05281 -22.13361 69.49262  1.000 41.04962  ? 173 LEU E CG  1 
ATOM   6270 C  CD1 . LEU E 1 193 ? -22.62682 -21.61634 69.51897  1.000 43.68075  ? 173 LEU E CD1 1 
ATOM   6271 C  CD2 . LEU E 1 193 ? -24.42515 -22.73879 70.83130  1.000 45.66065  ? 173 LEU E CD2 1 
ATOM   6272 N  N   . HIS E 1 194 ? -27.81408 -19.45586 69.58247  1.000 49.78829  ? 174 HIS E N   1 
ATOM   6273 C  CA  . HIS E 1 194 ? -28.63078 -18.26806 69.38030  1.000 51.62125  ? 174 HIS E CA  1 
ATOM   6274 C  C   . HIS E 1 194 ? -28.12743 -17.16377 70.29362  1.000 55.12887  ? 174 HIS E C   1 
ATOM   6275 O  O   . HIS E 1 194 ? -27.89256 -17.40142 71.48271  1.000 55.71187  ? 174 HIS E O   1 
ATOM   6276 C  CB  . HIS E 1 194 ? -30.11000 -18.56631 69.66866  1.000 61.24808  ? 174 HIS E CB  1 
ATOM   6277 C  CG  . HIS E 1 194 ? -30.94905 -17.34390 69.88454  1.000 63.08021  ? 174 HIS E CG  1 
ATOM   6278 N  ND1 . HIS E 1 194 ? -31.09660 -16.74981 71.12010  1.000 61.72486  ? 174 HIS E ND1 1 
ATOM   6279 C  CD2 . HIS E 1 194 ? -31.69718 -16.61266 69.02454  1.000 61.17097  ? 174 HIS E CD2 1 
ATOM   6280 C  CE1 . HIS E 1 194 ? -31.89234 -15.70082 71.00994  1.000 61.70827  ? 174 HIS E CE1 1 
ATOM   6281 N  NE2 . HIS E 1 194 ? -32.27081 -15.59567 69.74882  1.000 63.46095  ? 174 HIS E NE2 1 
ATOM   6282 N  N   . LYS E 1 195 ? -27.95583 -15.96443 69.74012  1.000 51.32300  ? 175 LYS E N   1 
ATOM   6283 C  CA  . LYS E 1 195 ? -27.66486 -14.77818 70.53583  1.000 48.84910  ? 175 LYS E CA  1 
ATOM   6284 C  C   . LYS E 1 195 ? -28.68237 -13.70268 70.19283  1.000 57.13953  ? 175 LYS E C   1 
ATOM   6285 O  O   . LYS E 1 195 ? -28.79307 -13.29979 69.03101  1.000 53.33748  ? 175 LYS E O   1 
ATOM   6286 C  CB  . LYS E 1 195 ? -26.24377 -14.25940 70.29593  1.000 46.83834  ? 175 LYS E CB  1 
ATOM   6287 C  CG  . LYS E 1 195 ? -25.97019 -12.94488 71.02279  1.000 47.07590  ? 175 LYS E CG  1 
ATOM   6288 C  CD  . LYS E 1 195 ? -24.56209 -12.42659 70.79172  1.000 48.14844  ? 175 LYS E CD  1 
ATOM   6289 C  CE  . LYS E 1 195 ? -24.37446 -11.05353 71.42880  1.000 42.08846  ? 175 LYS E CE  1 
ATOM   6290 N  NZ  . LYS E 1 195 ? -24.65542 -11.05470 72.89402  1.000 47.40905  ? 175 LYS E NZ  1 
ATOM   6291 N  N   . SER E 1 196 ? -29.42347 -13.24360 71.19769  1.000 60.53376  ? 176 SER E N   1 
ATOM   6292 C  CA  . SER E 1 196 ? -30.35097 -12.14129 70.99420  1.000 60.80426  ? 176 SER E CA  1 
ATOM   6293 C  C   . SER E 1 196 ? -29.58304 -10.84642 70.74656  1.000 59.16535  ? 176 SER E C   1 
ATOM   6294 O  O   . SER E 1 196 ? -28.50790 -10.61597 71.30677  1.000 51.10802  ? 176 SER E O   1 
ATOM   6295 C  CB  . SER E 1 196 ? -31.28260 -11.99323 72.19903  1.000 59.52605  ? 176 SER E CB  1 
ATOM   6296 O  OG  . SER E 1 196 ? -30.55764 -11.99843 73.41763  1.000 63.26364  ? 176 SER E OG  1 
ATOM   6297 N  N   . LEU E 1 197 ? -30.14085 -10.00026 69.88583  1.000 59.30815  ? 177 LEU E N   1 
ATOM   6298 C  CA  . LEU E 1 197 ? -29.48693 -8.77004  69.47014  1.000 59.92980  ? 177 LEU E CA  1 
ATOM   6299 C  C   . LEU E 1 197 ? -30.34778 -7.56502  69.81771  1.000 60.98186  ? 177 LEU E C   1 
ATOM   6300 O  O   . LEU E 1 197 ? -31.57461 -7.66268  69.91245  1.000 63.56283  ? 177 LEU E O   1 
ATOM   6301 C  CB  . LEU E 1 197 ? -29.20695 -8.77241  67.96183  1.000 60.94546  ? 177 LEU E CB  1 
ATOM   6302 C  CG  . LEU E 1 197 ? -28.34991 -9.90457  67.39755  1.000 52.61795  ? 177 LEU E CG  1 
ATOM   6303 C  CD1 . LEU E 1 197 ? -28.25725 -9.77726  65.88751  1.000 47.27442  ? 177 LEU E CD1 1 
ATOM   6304 C  CD2 . LEU E 1 197 ? -26.96576 -9.89647  68.02475  1.000 49.62469  ? 177 LEU E CD2 1 
ATOM   6305 N  N   . ARG E 1 198 ? -29.68795 -6.42445  70.01065  1.000 61.83691  ? 178 ARG E N   1 
ATOM   6306 C  CA  . ARG E 1 198 ? -30.38392 -5.15128  70.08952  1.000 76.94311  ? 178 ARG E CA  1 
ATOM   6307 C  C   . ARG E 1 198 ? -30.21244 -4.43296  68.76276  1.000 82.59702  ? 178 ARG E C   1 
ATOM   6308 O  O   . ARG E 1 198 ? -29.08631 -4.02748  68.43281  1.000 78.88710  ? 178 ARG E O   1 
ATOM   6309 C  CB  . ARG E 1 198 ? -29.84680 -4.29204  71.23270  1.000 79.18852  ? 178 ARG E CB  1 
ATOM   6310 C  CG  . ARG E 1 198 ? -30.37596 -2.86144  71.20940  1.000 85.54560  ? 178 ARG E CG  1 
ATOM   6311 C  CD  . ARG E 1 198 ? -30.05411 -2.10502  72.49002  1.000 89.40465  ? 178 ARG E CD  1 
ATOM   6312 N  NE  . ARG E 1 198 ? -30.78925 -0.84730  72.57089  1.000 99.73098  ? 178 ARG E NE  1 
ATOM   6313 C  CZ  . ARG E 1 198 ? -30.25300 0.35354   72.39709  1.000 103.95845 ? 178 ARG E CZ  1 
ATOM   6314 N  NH1 . ARG E 1 198 ? -28.95954 0.50717   72.16388  1.000 105.08139 ? 178 ARG E NH1 1 
ATOM   6315 N  NH2 . ARG E 1 198 ? -31.03384 1.42839   72.46419  1.000 90.77469  ? 178 ARG E NH2 1 
ATOM   6316 N  N   . PRO E 1 199 ? -31.26725 -4.27315  67.96398  1.000 87.77098  ? 179 PRO E N   1 
ATOM   6317 C  CA  . PRO E 1 199 ? -31.13209 -3.51453  66.71493  1.000 82.34160  ? 179 PRO E CA  1 
ATOM   6318 C  C   . PRO E 1 199 ? -30.67899 -2.08854  66.98966  1.000 87.19762  ? 179 PRO E C   1 
ATOM   6319 O  O   . PRO E 1 199 ? -31.13902 -1.44002  67.93222  1.000 89.95104  ? 179 PRO E O   1 
ATOM   6320 C  CB  . PRO E 1 199 ? -32.54405 -3.55566  66.11858  1.000 78.37062  ? 179 PRO E CB  1 
ATOM   6321 C  CG  . PRO E 1 199 ? -33.17595 -4.76379  66.73009  1.000 73.52281  ? 179 PRO E CG  1 
ATOM   6322 C  CD  . PRO E 1 199 ? -32.61175 -4.85504  68.11747  1.000 73.19248  ? 179 PRO E CD  1 
ATOM   6323 N  N   . ALA E 1 200 ? -29.75902 -1.60733  66.15828  1.000 86.65092  ? 180 ALA E N   1 
ATOM   6324 C  CA  . ALA E 1 200 ? -29.17264 -0.28750  66.32275  1.000 94.02184  ? 180 ALA E CA  1 
ATOM   6325 C  C   . ALA E 1 200 ? -29.18100 0.45066   64.99154  1.000 89.71424  ? 180 ALA E C   1 
ATOM   6326 O  O   . ALA E 1 200 ? -29.44927 -0.12528  63.93351  1.000 81.87298  ? 180 ALA E O   1 
ATOM   6327 C  CB  . ALA E 1 200 ? -27.74312 -0.37681  66.87258  1.000 92.88630  ? 180 ALA E CB  1 
ATOM   6328 N  N   . SER E 1 201 ? -28.88121 1.74910   65.06170  1.000 95.28413  ? 181 SER E N   1 
ATOM   6329 C  CA  . SER E 1 201 ? -28.76945 2.56593   63.86760  1.000 96.62949  ? 181 SER E CA  1 
ATOM   6330 C  C   . SER E 1 201 ? -27.63804 2.04540   62.98212  1.000 88.82201  ? 181 SER E C   1 
ATOM   6331 O  O   . SER E 1 201 ? -26.70640 1.39848   63.46857  1.000 92.59780  ? 181 SER E O   1 
ATOM   6332 C  CB  . SER E 1 201 ? -28.52709 4.02916   64.24688  1.000 88.96310  ? 181 SER E CB  1 
ATOM   6333 O  OG  . SER E 1 201 ? -27.42421 4.16092   65.12879  1.000 82.54438  ? 181 SER E OG  1 
ATOM   6334 N  N   . PRO E 1 202 ? -27.70628 2.30958   61.67140  1.000 86.46593  ? 182 PRO E N   1 
ATOM   6335 C  CA  . PRO E 1 202 ? -26.66748 1.78177   60.76419  1.000 83.44647  ? 182 PRO E CA  1 
ATOM   6336 C  C   . PRO E 1 202 ? -25.24292 2.13087   61.17533  1.000 83.95572  ? 182 PRO E C   1 
ATOM   6337 O  O   . PRO E 1 202 ? -24.40276 1.23140   61.30571  1.000 84.48570  ? 182 PRO E O   1 
ATOM   6338 C  CB  . PRO E 1 202 ? -27.05170 2.40516   59.41597  1.000 82.04791  ? 182 PRO E CB  1 
ATOM   6339 C  CG  . PRO E 1 202 ? -28.52900 2.60575   59.51033  1.000 77.23085  ? 182 PRO E CG  1 
ATOM   6340 C  CD  . PRO E 1 202 ? -28.79744 2.97907   60.93909  1.000 75.67008  ? 182 PRO E CD  1 
ATOM   6341 N  N   . GLY E 1 203 ? -24.94866 3.40963   61.38982  1.000 81.93514  ? 183 GLY E N   1 
ATOM   6342 C  CA  . GLY E 1 203 ? -23.61932 3.82972   61.79735  1.000 82.56765  ? 183 GLY E CA  1 
ATOM   6343 C  C   . GLY E 1 203 ? -22.52923 3.48041   60.80094  1.000 79.03908  ? 183 GLY E C   1 
ATOM   6344 O  O   . GLY E 1 203 ? -21.60822 4.26363   60.56920  1.000 66.92756  ? 183 GLY E O   1 
ATOM   6345 N  N   . GLU E 1 207 ? -25.64054 7.41145   55.11316  1.000 49.67367  ? 187 GLU E N   1 
ATOM   6346 C  CA  . GLU E 1 207 ? -26.55128 6.90493   54.09113  1.000 53.16058  ? 187 GLU E CA  1 
ATOM   6347 C  C   . GLU E 1 207 ? -25.80342 6.17723   52.97848  1.000 44.81360  ? 187 GLU E C   1 
ATOM   6348 O  O   . GLU E 1 207 ? -24.85231 6.70832   52.40642  1.000 47.57192  ? 187 GLU E O   1 
ATOM   6349 C  CB  . GLU E 1 207 ? -27.38076 8.04648   53.49596  1.000 51.81714  ? 187 GLU E CB  1 
ATOM   6350 C  CG  . GLU E 1 207 ? -28.17259 7.65056   52.25605  1.000 49.28452  ? 187 GLU E CG  1 
ATOM   6351 C  CD  . GLU E 1 207 ? -28.89896 8.82133   51.61641  1.000 46.01208  ? 187 GLU E CD  1 
ATOM   6352 O  OE1 . GLU E 1 207 ? -29.29930 9.75172   52.34830  1.000 46.52097  ? 187 GLU E OE1 1 
ATOM   6353 O  OE2 . GLU E 1 207 ? -29.06498 8.81151   50.37761  1.000 35.70791  ? 187 GLU E OE2 1 
ATOM   6354 N  N   . ASP E 1 208 ? -26.24142 4.95965   52.67462  1.000 44.79804  ? 188 ASP E N   1 
ATOM   6355 C  CA  . ASP E 1 208 ? -25.66206 4.18845   51.58088  1.000 43.85458  ? 188 ASP E CA  1 
ATOM   6356 C  C   . ASP E 1 208 ? -26.73840 3.77332   50.58117  1.000 53.63901  ? 188 ASP E C   1 
ATOM   6357 O  O   . ASP E 1 208 ? -26.55332 2.84159   49.79703  1.000 49.03426  ? 188 ASP E O   1 
ATOM   6358 C  CB  . ASP E 1 208 ? -24.92783 2.95542   52.11500  1.000 59.45537  ? 188 ASP E CB  1 
ATOM   6359 C  CG  . ASP E 1 208 ? -25.83792 2.01481   52.88743  1.000 60.83698  ? 188 ASP E CG  1 
ATOM   6360 O  OD1 . ASP E 1 208 ? -27.01907 2.35549   53.11437  1.000 62.21330  ? 188 ASP E OD1 1 
ATOM   6361 O  OD2 . ASP E 1 208 ? -25.36537 0.92629   53.27154  1.000 54.80377  ? 188 ASP E OD2 1 
ATOM   6362 O  OXT . ASP E 1 208 ? -27.82360 4.35620   50.54622  1.000 47.42587  ? 188 ASP E OXT 1 
ATOM   6363 N  N   . ALA F 1 34  ? -19.57692 -24.24409 85.70455  1.000 69.12785  ? 14  ALA F N   1 
ATOM   6364 C  CA  . ALA F 1 34  ? -18.17127 -24.50897 85.97364  1.000 70.75259  ? 14  ALA F CA  1 
ATOM   6365 C  C   . ALA F 1 34  ? -17.41367 -23.20742 86.22485  1.000 77.68404  ? 14  ALA F C   1 
ATOM   6366 O  O   . ALA F 1 34  ? -16.43622 -23.18362 86.97279  1.000 76.57171  ? 14  ALA F O   1 
ATOM   6367 C  CB  . ALA F 1 34  ? -17.54383 -25.27262 84.81650  1.000 68.05635  ? 14  ALA F CB  1 
ATOM   6368 N  N   . TRP F 1 35  ? -17.87192 -22.12759 85.59461  1.000 76.92643  ? 15  TRP F N   1 
ATOM   6369 C  CA  . TRP F 1 35  ? -17.32025 -20.79181 85.79247  1.000 77.59666  ? 15  TRP F CA  1 
ATOM   6370 C  C   . TRP F 1 35  ? -18.28312 -19.99934 86.66612  1.000 70.90190  ? 15  TRP F C   1 
ATOM   6371 O  O   . TRP F 1 35  ? -19.42817 -19.75160 86.26727  1.000 66.95739  ? 15  TRP F O   1 
ATOM   6372 C  CB  . TRP F 1 35  ? -17.09327 -20.08398 84.45628  1.000 71.66248  ? 15  TRP F CB  1 
ATOM   6373 C  CG  . TRP F 1 35  ? -16.02219 -20.70500 83.60815  1.000 69.74060  ? 15  TRP F CG  1 
ATOM   6374 C  CD1 . TRP F 1 35  ? -16.17330 -21.72254 82.71314  1.000 68.31203  ? 15  TRP F CD1 1 
ATOM   6375 C  CD2 . TRP F 1 35  ? -14.63565 -20.34160 83.57194  1.000 69.67870  ? 15  TRP F CD2 1 
ATOM   6376 N  NE1 . TRP F 1 35  ? -14.96786 -22.01853 82.12385  1.000 63.90189  ? 15  TRP F NE1 1 
ATOM   6377 C  CE2 . TRP F 1 35  ? -14.00749 -21.18482 82.63358  1.000 59.91696  ? 15  TRP F CE2 1 
ATOM   6378 C  CE3 . TRP F 1 35  ? -13.86468 -19.38687 84.24267  1.000 72.57245  ? 15  TRP F CE3 1 
ATOM   6379 C  CZ2 . TRP F 1 35  ? -12.64463 -21.10175 82.34900  1.000 61.83402  ? 15  TRP F CZ2 1 
ATOM   6380 C  CZ3 . TRP F 1 35  ? -12.51291 -19.30561 83.95756  1.000 62.71150  ? 15  TRP F CZ3 1 
ATOM   6381 C  CH2 . TRP F 1 35  ? -11.91701 -20.15757 83.02084  1.000 64.48129  ? 15  TRP F CH2 1 
ATOM   6382 N  N   . GLN F 1 36  ? -17.81820 -19.60126 87.84839  1.000 63.98887  ? 16  GLN F N   1 
ATOM   6383 C  CA  . GLN F 1 36  ? -18.66127 -18.94349 88.83782  1.000 72.25092  ? 16  GLN F CA  1 
ATOM   6384 C  C   . GLN F 1 36  ? -18.05055 -17.60812 89.23505  1.000 66.38825  ? 16  GLN F C   1 
ATOM   6385 O  O   . GLN F 1 36  ? -16.85254 -17.53125 89.51890  1.000 57.84432  ? 16  GLN F O   1 
ATOM   6386 C  CB  . GLN F 1 36  ? -18.83829 -19.82296 90.07898  1.000 72.17496  ? 16  GLN F CB  1 
ATOM   6387 C  CG  . GLN F 1 36  ? -20.24951 -19.83348 90.64162  1.000 70.88163  ? 16  GLN F CG  1 
ATOM   6388 C  CD  . GLN F 1 36  ? -21.12091 -20.88876 89.99159  1.000 71.70874  ? 16  GLN F CD  1 
ATOM   6389 O  OE1 . GLN F 1 36  ? -20.76535 -22.06690 89.95831  1.000 76.24168  ? 16  GLN F OE1 1 
ATOM   6390 N  NE2 . GLN F 1 36  ? -22.26623 -20.47117 89.46551  1.000 71.15993  ? 16  GLN F NE2 1 
ATOM   6391 N  N   . TRP F 1 37  ? -18.87118 -16.56282 89.26434  1.000 64.77002  ? 17  TRP F N   1 
ATOM   6392 C  CA  . TRP F 1 37  ? -18.43857 -15.25827 89.74168  1.000 64.78475  ? 17  TRP F CA  1 
ATOM   6393 C  C   . TRP F 1 37  ? -18.86462 -15.06334 91.19063  1.000 61.62513  ? 17  TRP F C   1 
ATOM   6394 O  O   . TRP F 1 37  ? -19.86200 -15.62825 91.64633  1.000 65.40293  ? 17  TRP F O   1 
ATOM   6395 C  CB  . TRP F 1 37  ? -19.00245 -14.13149 88.87156  1.000 51.55747  ? 17  TRP F CB  1 
ATOM   6396 C  CG  . TRP F 1 37  ? -18.23433 -13.93899 87.60323  1.000 63.67863  ? 17  TRP F CG  1 
ATOM   6397 C  CD1 . TRP F 1 37  ? -18.55767 -14.41794 86.36785  1.000 57.53658  ? 17  TRP F CD1 1 
ATOM   6398 C  CD2 . TRP F 1 37  ? -16.99890 -13.22921 87.44805  1.000 62.58606  ? 17  TRP F CD2 1 
ATOM   6399 N  NE1 . TRP F 1 37  ? -17.60448 -14.04531 85.45133  1.000 49.20328  ? 17  TRP F NE1 1 
ATOM   6400 C  CE2 . TRP F 1 37  ? -16.63632 -13.31516 86.08920  1.000 56.16953  ? 17  TRP F CE2 1 
ATOM   6401 C  CE3 . TRP F 1 37  ? -16.16670 -12.52637 88.32549  1.000 57.24383  ? 17  TRP F CE3 1 
ATOM   6402 C  CZ2 . TRP F 1 37  ? -15.47687 -12.72687 85.58724  1.000 53.48098  ? 17  TRP F CZ2 1 
ATOM   6403 C  CZ3 . TRP F 1 37  ? -15.01667 -11.94168 87.82513  1.000 51.78943  ? 17  TRP F CZ3 1 
ATOM   6404 C  CH2 . TRP F 1 37  ? -14.68382 -12.04443 86.46843  1.000 56.47316  ? 17  TRP F CH2 1 
ATOM   6405 N  N   . GLU F 1 38  ? -18.08992 -14.26004 91.91566  1.000 65.26925  ? 18  GLU F N   1 
ATOM   6406 C  CA  . GLU F 1 38  ? -18.38089 -14.00334 93.31687  1.000 61.76466  ? 18  GLU F CA  1 
ATOM   6407 C  C   . GLU F 1 38  ? -17.86789 -12.62270 93.69715  1.000 60.94650  ? 18  GLU F C   1 
ATOM   6408 O  O   . GLU F 1 38  ? -16.89359 -12.12213 93.12525  1.000 61.93927  ? 18  GLU F O   1 
ATOM   6409 C  CB  . GLU F 1 38  ? -17.75031 -15.06585 94.23055  1.000 54.37102  ? 18  GLU F CB  1 
ATOM   6410 C  CG  . GLU F 1 38  ? -16.25615 -14.88074 94.46524  1.000 55.69675  ? 18  GLU F CG  1 
ATOM   6411 C  CD  . GLU F 1 38  ? -15.66434 -15.93870 95.37608  1.000 67.98237  ? 18  GLU F CD  1 
ATOM   6412 O  OE1 . GLU F 1 38  ? -15.94504 -17.13562 95.15869  1.000 79.26252  ? 18  GLU F OE1 1 
ATOM   6413 O  OE2 . GLU F 1 38  ? -14.92192 -15.57213 96.31227  1.000 65.46900  ? 18  GLU F OE2 1 
ATOM   6414 N  N   . VAL F 1 39  ? -18.54882 -12.00487 94.65814  1.000 66.40736  ? 19  VAL F N   1 
ATOM   6415 C  CA  . VAL F 1 39  ? -18.01756 -10.83144 95.34265  1.000 54.06240  ? 19  VAL F CA  1 
ATOM   6416 C  C   . VAL F 1 39  ? -17.07585 -11.34932 96.42463  1.000 52.47406  ? 19  VAL F C   1 
ATOM   6417 O  O   . VAL F 1 39  ? -17.51742 -11.94697 97.40895  1.000 66.62620  ? 19  VAL F O   1 
ATOM   6418 C  CB  . VAL F 1 39  ? -19.13270 -9.96401  95.93615  1.000 56.50748  ? 19  VAL F CB  1 
ATOM   6419 C  CG1 . VAL F 1 39  ? -18.55978 -8.66741  96.48577  1.000 58.98412  ? 19  VAL F CG1 1 
ATOM   6420 C  CG2 . VAL F 1 39  ? -20.20484 -9.67906  94.88733  1.000 46.23395  ? 19  VAL F CG2 1 
ATOM   6421 N  N   . SER F 1 40  ? -15.77630 -11.13686 96.23504  1.000 49.10570  ? 20  SER F N   1 
ATOM   6422 C  CA  . SER F 1 40  ? -14.77865 -11.82439 97.04429  1.000 51.64228  ? 20  SER F CA  1 
ATOM   6423 C  C   . SER F 1 40  ? -14.82154 -11.37354 98.50035  1.000 57.60960  ? 20  SER F C   1 
ATOM   6424 O  O   . SER F 1 40  ? -15.05741 -10.20012 98.80222  1.000 63.27695  ? 20  SER F O   1 
ATOM   6425 C  CB  . SER F 1 40  ? -13.38181 -11.59213 96.47167  1.000 51.02935  ? 20  SER F CB  1 
ATOM   6426 O  OG  . SER F 1 40  ? -12.40721 -12.29573 97.22253  1.000 63.56722  ? 20  SER F OG  1 
ATOM   6427 N  N   . ARG F 1 41  ? -14.59761 -12.33035 99.40634  1.000 59.77213  ? 21  ARG F N   1 
ATOM   6428 C  CA  . ARG F 1 41  ? -14.43362 -12.06111 100.82735 1.000 63.88115  ? 21  ARG F CA  1 
ATOM   6429 C  C   . ARG F 1 41  ? -13.06317 -12.45145 101.36049 1.000 59.49736  ? 21  ARG F C   1 
ATOM   6430 O  O   . ARG F 1 41  ? -12.73616 -12.08863 102.49644 1.000 61.86798  ? 21  ARG F O   1 
ATOM   6431 C  CB  . ARG F 1 41  ? -15.50142 -12.80069 101.64991 1.000 48.55109  ? 21  ARG F CB  1 
ATOM   6432 C  CG  . ARG F 1 41  ? -16.92912 -12.36116 101.39215 1.000 52.02000  ? 21  ARG F CG  1 
ATOM   6433 C  CD  . ARG F 1 41  ? -17.87016 -13.08285 102.33778 1.000 53.16761  ? 21  ARG F CD  1 
ATOM   6434 N  NE  . ARG F 1 41  ? -19.25388 -12.64240 102.21578 1.000 58.88813  ? 21  ARG F NE  1 
ATOM   6435 C  CZ  . ARG F 1 41  ? -20.21341 -12.97324 103.06879 1.000 62.57008  ? 21  ARG F CZ  1 
ATOM   6436 N  NH1 . ARG F 1 41  ? -19.96524 -13.72606 104.12814 1.000 60.01589  ? 21  ARG F NH1 1 
ATOM   6437 N  NH2 . ARG F 1 41  ? -21.45142 -12.53691 102.85552 1.000 66.24589  ? 21  ARG F NH2 1 
ATOM   6438 N  N   . ASP F 1 42  ? -12.26027 -13.17701 100.58474 1.000 48.80463  ? 22  ASP F N   1 
ATOM   6439 C  CA  . ASP F 1 42  ? -10.96761 -13.68757 101.02854 1.000 52.64845  ? 22  ASP F CA  1 
ATOM   6440 C  C   . ASP F 1 42  ? -9.88299  -12.71587 100.57527 1.000 58.85246  ? 22  ASP F C   1 
ATOM   6441 O  O   . ASP F 1 42  ? -9.53047  -12.67590 99.39202  1.000 72.25496  ? 22  ASP F O   1 
ATOM   6442 C  CB  . ASP F 1 42  ? -10.72901 -15.08955 100.46883 1.000 63.63985  ? 22  ASP F CB  1 
ATOM   6443 C  CG  . ASP F 1 42  ? -9.63559  -15.84275 101.20538 1.000 67.83577  ? 22  ASP F CG  1 
ATOM   6444 O  OD1 . ASP F 1 42  ? -8.69861  -15.19909 101.72167 1.000 64.04605  ? 22  ASP F OD1 1 
ATOM   6445 O  OD2 . ASP F 1 42  ? -9.71483  -17.08814 101.26298 1.000 62.83908  ? 22  ASP F OD2 1 
ATOM   6446 N  N   . THR F 1 43  ? -9.35351  -11.93583 101.52048 1.000 58.86540  ? 23  THR F N   1 
ATOM   6447 C  CA  . THR F 1 43  ? -8.31423  -10.96565 101.18797 1.000 53.18727  ? 23  THR F CA  1 
ATOM   6448 C  C   . THR F 1 43  ? -6.98890  -11.65429 100.88582 1.000 58.26494  ? 23  THR F C   1 
ATOM   6449 O  O   . THR F 1 43  ? -6.28450  -11.27092 99.94290  1.000 57.41583  ? 23  THR F O   1 
ATOM   6450 C  CB  . THR F 1 43  ? -8.15658  -9.95959  102.33059 1.000 54.90699  ? 23  THR F CB  1 
ATOM   6451 O  OG1 . THR F 1 43  ? -9.26580  -9.05017  102.32476 1.000 48.64622  ? 23  THR F OG1 1 
ATOM   6452 C  CG2 . THR F 1 43  ? -6.85539  -9.17903  102.20145 1.000 48.08329  ? 23  THR F CG2 1 
ATOM   6453 N  N   . GLY F 1 44  ? -6.63565  -12.67316 101.67310 1.000 60.33154  ? 24  GLY F N   1 
ATOM   6454 C  CA  . GLY F 1 44  ? -5.39210  -13.38603 101.43221 1.000 58.59782  ? 24  GLY F CA  1 
ATOM   6455 C  C   . GLY F 1 44  ? -5.34723  -14.04061 100.06534 1.000 63.04390  ? 24  GLY F C   1 
ATOM   6456 O  O   . GLY F 1 44  ? -4.33124  -13.97769 99.37107  1.000 58.76997  ? 24  GLY F O   1 
ATOM   6457 N  N   . GLU F 1 45  ? -6.45278  -14.66524 99.65375  1.000 61.87333  ? 25  GLU F N   1 
ATOM   6458 C  CA  . GLU F 1 45  ? -6.49200  -15.31563 98.34751  1.000 65.15721  ? 25  GLU F CA  1 
ATOM   6459 C  C   . GLU F 1 45  ? -6.41699  -14.29692 97.21549  1.000 64.49961  ? 25  GLU F C   1 
ATOM   6460 O  O   . GLU F 1 45  ? -5.69562  -14.50621 96.23039  1.000 67.51490  ? 25  GLU F O   1 
ATOM   6461 C  CB  . GLU F 1 45  ? -7.75416  -16.17017 98.23396  1.000 64.64248  ? 25  GLU F CB  1 
ATOM   6462 C  CG  . GLU F 1 45  ? -8.29424  -16.31601 96.82654  1.000 65.44250  ? 25  GLU F CG  1 
ATOM   6463 C  CD  . GLU F 1 45  ? -9.06490  -17.60374 96.64145  1.000 70.36769  ? 25  GLU F CD  1 
ATOM   6464 O  OE1 . GLU F 1 45  ? -8.42315  -18.67399 96.60879  1.000 78.17592  ? 25  GLU F OE1 1 
ATOM   6465 O  OE2 . GLU F 1 45  ? -10.30807 -17.54962 96.54387  1.000 63.73349  ? 25  GLU F OE2 1 
ATOM   6466 N  N   . VAL F 1 46  ? -7.15371  -13.18952 97.33936  1.000 65.53114  ? 26  VAL F N   1 
ATOM   6467 C  CA  . VAL F 1 46  ? -7.10113  -12.13471 96.32835  1.000 61.39710  ? 26  VAL F CA  1 
ATOM   6468 C  C   . VAL F 1 46  ? -5.67991  -11.60453 96.18957  1.000 63.21432  ? 26  VAL F C   1 
ATOM   6469 O  O   . VAL F 1 46  ? -5.15520  -11.46319 95.07840  1.000 68.26223  ? 26  VAL F O   1 
ATOM   6470 C  CB  . VAL F 1 46  ? -8.09077  -11.00663 96.67499  1.000 58.98785  ? 26  VAL F CB  1 
ATOM   6471 C  CG1 . VAL F 1 46  ? -7.73052  -9.73053  95.93063  1.000 53.91460  ? 26  VAL F CG1 1 
ATOM   6472 C  CG2 . VAL F 1 46  ? -9.50949  -11.42948 96.34312  1.000 59.32443  ? 26  VAL F CG2 1 
ATOM   6473 N  N   . HIS F 1 47  ? -5.03134  -11.31230 97.31956  1.000 61.70648  ? 27  HIS F N   1 
ATOM   6474 C  CA  . HIS F 1 47  ? -3.68311  -10.75785 97.26827  1.000 64.43590  ? 27  HIS F CA  1 
ATOM   6475 C  C   . HIS F 1 47  ? -2.68885  -11.77386 96.72041  1.000 67.74980  ? 27  HIS F C   1 
ATOM   6476 O  O   . HIS F 1 47  ? -1.77217  -11.41104 95.97411  1.000 67.88167  ? 27  HIS F O   1 
ATOM   6477 C  CB  . HIS F 1 47  ? -3.25595  -10.28177 98.65514  1.000 59.21904  ? 27  HIS F CB  1 
ATOM   6478 C  CG  . HIS F 1 47  ? -2.20003  -9.22240  98.62712  1.000 64.81094  ? 27  HIS F CG  1 
ATOM   6479 N  ND1 . HIS F 1 47  ? -2.49995  -7.87757  98.58895  1.000 68.50876  ? 27  HIS F ND1 1 
ATOM   6480 C  CD2 . HIS F 1 47  ? -0.84862  -9.30781  98.61862  1.000 63.00161  ? 27  HIS F CD2 1 
ATOM   6481 C  CE1 . HIS F 1 47  ? -1.37882  -7.17975  98.56435  1.000 71.28220  ? 27  HIS F CE1 1 
ATOM   6482 N  NE2 . HIS F 1 47  ? -0.36237  -8.02342  98.58228  1.000 81.57619  ? 27  HIS F NE2 1 
ATOM   6483 N  N   . ALA F 1 48  ? -2.85879  -13.05155 97.07157  1.000 64.39478  ? 28  ALA F N   1 
ATOM   6484 C  CA  . ALA F 1 48  ? -1.97245  -14.09008 96.56098  1.000 73.20007  ? 28  ALA F CA  1 
ATOM   6485 C  C   . ALA F 1 48  ? -2.08688  -14.20734 95.04822  1.000 71.45044  ? 28  ALA F C   1 
ATOM   6486 O  O   . ALA F 1 48  ? -1.07370  -14.25369 94.33873  1.000 69.66280  ? 28  ALA F O   1 
ATOM   6487 C  CB  . ALA F 1 48  ? -2.29227  -15.42499 97.23342  1.000 63.80686  ? 28  ALA F CB  1 
ATOM   6488 N  N   . MET F 1 49  ? -3.31933  -14.25605 94.53382  1.000 69.09077  ? 29  MET F N   1 
ATOM   6489 C  CA  . MET F 1 49  ? -3.49757  -14.32246 93.08801  1.000 73.55036  ? 29  MET F CA  1 
ATOM   6490 C  C   . MET F 1 49  ? -2.94246  -13.08041 92.40712  1.000 77.71595  ? 29  MET F C   1 
ATOM   6491 O  O   . MET F 1 49  ? -2.29052  -13.18005 91.36369  1.000 74.39427  ? 29  MET F O   1 
ATOM   6492 C  CB  . MET F 1 49  ? -4.96851  -14.49526 92.72334  1.000 72.46042  ? 29  MET F CB  1 
ATOM   6493 C  CG  . MET F 1 49  ? -5.18338  -14.54712 91.21429  1.000 77.57140  ? 29  MET F CG  1 
ATOM   6494 S  SD  . MET F 1 49  ? -6.88539  -14.25799 90.72461  1.000 97.29973  ? 29  MET F SD  1 
ATOM   6495 C  CE  . MET F 1 49  ? -7.71267  -15.37252 91.83868  1.000 76.38258  ? 29  MET F CE  1 
ATOM   6496 N  N   . LEU F 1 50  ? -3.19154  -11.89941 92.98016  1.000 77.78953  ? 30  LEU F N   1 
ATOM   6497 C  CA  . LEU F 1 50  ? -2.69870  -10.66656 92.37431  1.000 78.87934  ? 30  LEU F CA  1 
ATOM   6498 C  C   . LEU F 1 50  ? -1.17892  -10.65532 92.30105  1.000 80.81819  ? 30  LEU F C   1 
ATOM   6499 O  O   . LEU F 1 50  ? -0.60617  -10.30429 91.26495  1.000 83.80997  ? 30  LEU F O   1 
ATOM   6500 C  CB  . LEU F 1 50  ? -3.20316  -9.45466  93.15513  1.000 73.98888  ? 30  LEU F CB  1 
ATOM   6501 C  CG  . LEU F 1 50  ? -2.76558  -8.09800  92.60418  1.000 75.65354  ? 30  LEU F CG  1 
ATOM   6502 C  CD1 . LEU F 1 50  ? -3.22260  -7.93295  91.16148  1.000 71.63233  ? 30  LEU F CD1 1 
ATOM   6503 C  CD2 . LEU F 1 50  ? -3.28993  -6.96517  93.47036  1.000 72.68220  ? 30  LEU F CD2 1 
ATOM   6504 N  N   . CYS F 1 51  ? -0.50579  -11.05937 93.38103  1.000 80.98444  ? 31  CYS F N   1 
ATOM   6505 C  CA  . CYS F 1 51  ? 0.95391   -11.03204 93.38206  1.000 83.32130  ? 31  CYS F CA  1 
ATOM   6506 C  C   . CYS F 1 51  ? 1.53781   -12.09611 92.45897  1.000 88.22474  ? 31  CYS F C   1 
ATOM   6507 O  O   . CYS F 1 51  ? 2.50984   -11.83078 91.74166  1.000 96.15112  ? 31  CYS F O   1 
ATOM   6508 C  CB  . CYS F 1 51  ? 1.48269   -11.19913 94.80412  1.000 75.12909  ? 31  CYS F CB  1 
ATOM   6509 S  SG  . CYS F 1 51  ? 1.19499   -9.75992  95.85947  1.000 81.60097  ? 31  CYS F SG  1 
ATOM   6510 N  N   . ALA F 1 52  ? 0.96345   -13.30396 92.45665  1.000 86.81282  ? 32  ALA F N   1 
ATOM   6511 C  CA  . ALA F 1 52  ? 1.44598   -14.34166 91.55056  1.000 90.16830  ? 32  ALA F CA  1 
ATOM   6512 C  C   . ALA F 1 52  ? 1.25449   -13.92110 90.10177  1.000 90.32823  ? 32  ALA F C   1 
ATOM   6513 O  O   . ALA F 1 52  ? 2.14205   -14.12469 89.25780  1.000 96.60779  ? 32  ALA F O   1 
ATOM   6514 C  CB  . ALA F 1 52  ? 0.71907   -15.65760 91.82767  1.000 84.46297  ? 32  ALA F CB  1 
ATOM   6515 N  N   . CYS F 1 53  ? 0.10352   -13.30280 89.80492  1.000 85.11518  ? 33  CYS F N   1 
ATOM   6516 C  CA  . CYS F 1 53  ? -0.18978  -12.86540 88.44659  1.000 85.64268  ? 33  CYS F CA  1 
ATOM   6517 C  C   . CYS F 1 53  ? 0.73216   -11.72969 88.02877  1.000 90.73420  ? 33  CYS F C   1 
ATOM   6518 O  O   . CYS F 1 53  ? 1.18730   -11.69453 86.88223  1.000 90.93909  ? 33  CYS F O   1 
ATOM   6519 C  CB  . CYS F 1 53  ? -1.66208  -12.44658 88.31896  1.000 82.34739  ? 33  CYS F CB  1 
ATOM   6520 S  SG  . CYS F 1 53  ? -2.32013  -12.34418 86.59713  1.000 103.86876 ? 33  CYS F SG  1 
ATOM   6521 N  N   . ASP F 1 54  ? 1.02308   -10.79482 88.94087  1.000 89.61523  ? 34  ASP F N   1 
ATOM   6522 C  CA  . ASP F 1 54  ? 1.96851   -9.72445  88.63392  1.000 97.06470  ? 34  ASP F CA  1 
ATOM   6523 C  C   . ASP F 1 54  ? 3.36589   -10.28023 88.39106  1.000 98.99808  ? 34  ASP F C   1 
ATOM   6524 O  O   . ASP F 1 54  ? 4.07534   -9.82914  87.48288  1.000 105.90251 ? 34  ASP F O   1 
ATOM   6525 C  CB  . ASP F 1 54  ? 1.98687   -8.70005  89.76946  1.000 104.13352 ? 34  ASP F CB  1 
ATOM   6526 C  CG  . ASP F 1 54  ? 0.69834   -7.90545  89.85865  1.000 95.82252  ? 34  ASP F CG  1 
ATOM   6527 O  OD1 . ASP F 1 54  ? 0.00780   -7.76522  88.82717  1.000 96.42530  ? 34  ASP F OD1 1 
ATOM   6528 O  OD2 . ASP F 1 54  ? 0.38220   -7.41052  90.95956  1.000 91.65275  ? 34  ASP F OD2 1 
ATOM   6529 N  N   . ALA F 1 55  ? 3.77477   -11.26983 89.18956  1.000 96.84870  ? 35  ALA F N   1 
ATOM   6530 C  CA  . ALA F 1 55  ? 5.08832   -11.87484 89.00176  1.000 99.27019  ? 35  ALA F CA  1 
ATOM   6531 C  C   . ALA F 1 55  ? 5.18312   -12.57739 87.65468  1.000 106.19436 ? 35  ALA F C   1 
ATOM   6532 O  O   . ALA F 1 55  ? 6.21342   -12.49434 86.97644  1.000 112.04604 ? 35  ALA F O   1 
ATOM   6533 C  CB  . ALA F 1 55  ? 5.38988   -12.84956 90.14012  1.000 90.58114  ? 35  ALA F CB  1 
ATOM   6534 N  N   . HIS F 1 56  ? 4.11993   -13.27595 87.24959  1.000 103.67761 ? 36  HIS F N   1 
ATOM   6535 C  CA  . HIS F 1 56  ? 4.12073   -13.91288 85.93540  1.000 103.40500 ? 36  HIS F CA  1 
ATOM   6536 C  C   . HIS F 1 56  ? 4.16721   -12.86977 84.82245  1.000 109.75449 ? 36  HIS F C   1 
ATOM   6537 O  O   . HIS F 1 56  ? 5.00351   -12.95048 83.91486  1.000 104.80182 ? 36  HIS F O   1 
ATOM   6538 C  CB  . HIS F 1 56  ? 2.89329   -14.81606 85.78480  1.000 92.96543  ? 36  HIS F CB  1 
ATOM   6539 C  CG  . HIS F 1 56  ? 2.90027   -15.65271 84.53931  1.000 96.51889  ? 36  HIS F CG  1 
ATOM   6540 N  ND1 . HIS F 1 56  ? 3.25563   -15.15477 83.30362  1.000 97.15717  ? 36  HIS F ND1 1 
ATOM   6541 C  CD2 . HIS F 1 56  ? 2.59454   -16.95716 84.34160  1.000 95.61230  ? 36  HIS F CD2 1 
ATOM   6542 C  CE1 . HIS F 1 56  ? 3.16946   -16.11404 82.40001  1.000 92.22224  ? 36  HIS F CE1 1 
ATOM   6543 N  NE2 . HIS F 1 56  ? 2.76948   -17.21821 83.00378  1.000 90.65935  ? 36  HIS F NE2 1 
ATOM   6544 N  N   . GLN F 1 57  ? 3.27117   -11.87908 84.87673  1.000 112.29560 ? 37  GLN F N   1 
ATOM   6545 C  CA  . GLN F 1 57  ? 3.16521   -10.90281 83.79629  1.000 110.62863 ? 37  GLN F CA  1 
ATOM   6546 C  C   . GLN F 1 57  ? 4.40563   -10.02469 83.69483  1.000 115.90749 ? 37  GLN F C   1 
ATOM   6547 O  O   . GLN F 1 57  ? 4.68717   -9.47791  82.62226  1.000 113.23144 ? 37  GLN F O   1 
ATOM   6548 C  CB  . GLN F 1 57  ? 1.91661   -10.04165 83.98974  1.000 110.80844 ? 37  GLN F CB  1 
ATOM   6549 C  CG  . GLN F 1 57  ? 0.60896   -10.80636 83.82590  1.000 117.63792 ? 37  GLN F CG  1 
ATOM   6550 C  CD  . GLN F 1 57  ? -0.61130  -9.95211  84.12313  1.000 117.66624 ? 37  GLN F CD  1 
ATOM   6551 O  OE1 . GLN F 1 57  ? -0.55546  -9.02683  84.93473  1.000 107.07475 ? 37  GLN F OE1 1 
ATOM   6552 N  NE2 . GLN F 1 57  ? -1.72196  -10.25906 83.46382  1.000 110.97671 ? 37  GLN F NE2 1 
ATOM   6553 N  N   . ALA F 1 58  ? 5.15036   -9.86762  84.79133  1.000 114.09947 ? 38  ALA F N   1 
ATOM   6554 C  CA  . ALA F 1 58  ? 6.38974   -9.10118  84.73217  1.000 115.28499 ? 38  ALA F CA  1 
ATOM   6555 C  C   . ALA F 1 58  ? 7.43053   -9.80832  83.87438  1.000 121.10315 ? 38  ALA F C   1 
ATOM   6556 O  O   . ALA F 1 58  ? 8.16755   -9.15805  83.12326  1.000 115.56099 ? 38  ALA F O   1 
ATOM   6557 C  CB  . ALA F 1 58  ? 6.92734   -8.86146  86.14233  1.000 103.30878 ? 38  ALA F CB  1 
ATOM   6558 N  N   . ALA F 1 59  ? 7.49934   -11.13566 83.97261  1.000 118.85557 ? 39  ALA F N   1 
ATOM   6559 C  CA  . ALA F 1 59  ? 8.41611   -11.95355 83.17825  1.000 110.07247 ? 39  ALA F CA  1 
ATOM   6560 C  C   . ALA F 1 59  ? 9.86542   -11.49576 83.32570  1.000 111.16065 ? 39  ALA F C   1 
ATOM   6561 O  O   . ALA F 1 59  ? 10.66393  -11.62723 82.39902  1.000 107.07475 ? 39  ALA F O   1 
ATOM   6562 C  CB  . ALA F 1 59  ? 7.99914   -11.94043 81.71016  1.000 98.09709  ? 39  ALA F CB  1 
ATOM   6563 N  N   . SER F 1 64  ? 9.22419   -5.49943  85.62244  1.000 105.60768 ? 44  SER F N   1 
ATOM   6564 C  CA  . SER F 1 64  ? 9.20237   -5.73910  87.06051  1.000 112.39661 ? 44  SER F CA  1 
ATOM   6565 C  C   . SER F 1 64  ? 7.79049   -5.57905  87.61624  1.000 116.70239 ? 44  SER F C   1 
ATOM   6566 O  O   . SER F 1 64  ? 7.05996   -4.66792  87.22581  1.000 117.21692 ? 44  SER F O   1 
ATOM   6567 C  CB  . SER F 1 64  ? 10.16421  -4.78977  87.77818  1.000 106.37596 ? 44  SER F CB  1 
ATOM   6568 O  OG  . SER F 1 64  ? 9.78350   -3.43813  87.58913  1.000 93.08936  ? 44  SER F OG  1 
ATOM   6569 N  N   . ALA F 1 65  ? 7.41542   -6.46879  88.53007  1.000 115.51590 ? 45  ALA F N   1 
ATOM   6570 C  CA  . ALA F 1 65  ? 6.07568   -6.43074  89.09594  1.000 111.58220 ? 45  ALA F CA  1 
ATOM   6571 C  C   . ALA F 1 65  ? 5.92263   -5.22205  90.01725  1.000 113.48053 ? 45  ALA F C   1 
ATOM   6572 O  O   . ALA F 1 65  ? 6.86488   -4.85715  90.72798  1.000 107.10142 ? 45  ALA F O   1 
ATOM   6573 C  CB  . ALA F 1 65  ? 5.78196   -7.71522  89.86866  1.000 106.40357 ? 45  ALA F CB  1 
ATOM   6574 N  N   . PRO F 1 66  ? 4.75703   -4.58061  90.02563  1.000 108.17436 ? 46  PRO F N   1 
ATOM   6575 C  CA  . PRO F 1 66  ? 4.55033   -3.43872  90.92082  1.000 110.72099 ? 46  PRO F CA  1 
ATOM   6576 C  C   . PRO F 1 66  ? 4.39873   -3.88159  92.36841  1.000 103.52683 ? 46  PRO F C   1 
ATOM   6577 O  O   . PRO F 1 66  ? 4.03234   -5.01958  92.67077  1.000 99.45914  ? 46  PRO F O   1 
ATOM   6578 C  CB  . PRO F 1 66  ? 3.25757   -2.80669  90.39573  1.000 106.48336 ? 46  PRO F CB  1 
ATOM   6579 C  CG  . PRO F 1 66  ? 2.52603   -3.94386  89.76304  1.000 98.78673  ? 46  PRO F CG  1 
ATOM   6580 C  CD  . PRO F 1 66  ? 3.58435   -4.83611  89.17087  1.000 102.97207 ? 46  PRO F CD  1 
ATOM   6581 N  N   . ALA F 1 67  ? 4.69064   -2.94970  93.27276  1.000 98.40825  ? 47  ALA F N   1 
ATOM   6582 C  CA  . ALA F 1 67  ? 4.56689   -3.20478  94.70237  1.000 98.24297  ? 47  ALA F CA  1 
ATOM   6583 C  C   . ALA F 1 67  ? 3.10149   -3.11202  95.11031  1.000 98.72049  ? 47  ALA F C   1 
ATOM   6584 O  O   . ALA F 1 67  ? 2.48235   -2.04976  94.98526  1.000 99.18163  ? 47  ALA F O   1 
ATOM   6585 C  CB  . ALA F 1 67  ? 5.41430   -2.21402  95.49675  1.000 86.24907  ? 47  ALA F CB  1 
ATOM   6586 N  N   . ARG F 1 68  ? 2.54872   -4.21919  95.59625  1.000 90.07282  ? 48  ARG F N   1 
ATOM   6587 C  CA  . ARG F 1 68  ? 1.14858   -4.28822  95.98856  1.000 87.91699  ? 48  ARG F CA  1 
ATOM   6588 C  C   . ARG F 1 68  ? 1.00651   -4.05091  97.48645  1.000 81.53976  ? 48  ARG F C   1 
ATOM   6589 O  O   . ARG F 1 68  ? 1.80400   -4.55053  98.28568  1.000 91.68662  ? 48  ARG F O   1 
ATOM   6590 C  CB  . ARG F 1 68  ? 0.54291   -5.64254  95.61368  1.000 93.31446  ? 48  ARG F CB  1 
ATOM   6591 C  CG  . ARG F 1 68  ? 0.55583   -5.94030  94.12072  1.000 90.45232  ? 48  ARG F CG  1 
ATOM   6592 C  CD  . ARG F 1 68  ? -0.24574  -4.90980  93.33911  1.000 84.60101  ? 48  ARG F CD  1 
ATOM   6593 N  NE  . ARG F 1 68  ? -0.39649  -5.28589  91.93828  1.000 85.51216  ? 48  ARG F NE  1 
ATOM   6594 C  CZ  . ARG F 1 68  ? -1.11734  -4.61074  91.05332  1.000 81.15404  ? 48  ARG F CZ  1 
ATOM   6595 N  NH1 . ARG F 1 68  ? -1.76464  -3.50633  91.38707  1.000 76.14476  ? 48  ARG F NH1 1 
ATOM   6596 N  NH2 . ARG F 1 68  ? -1.19323  -5.05680  89.80263  1.000 81.04271  ? 48  ARG F NH2 1 
ATOM   6597 N  N   . ARG F 1 69  ? -0.01668  -3.28763  97.85873  1.000 77.82840  ? 49  ARG F N   1 
ATOM   6598 C  CA  . ARG F 1 69  ? -0.27584  -2.93083  99.24747  1.000 78.29234  ? 49  ARG F CA  1 
ATOM   6599 C  C   . ARG F 1 69  ? -1.40731  -3.79988  99.78490  1.000 74.24119  ? 49  ARG F C   1 
ATOM   6600 O  O   . ARG F 1 69  ? -2.50652  -3.81319  99.22032  1.000 69.76378  ? 49  ARG F O   1 
ATOM   6601 C  CB  . ARG F 1 69  ? -0.62461  -1.44680  99.36213  1.000 80.33165  ? 49  ARG F CB  1 
ATOM   6602 C  CG  . ARG F 1 69  ? -1.12985  -1.01488  100.72602 1.000 85.55605  ? 49  ARG F CG  1 
ATOM   6603 C  CD  . ARG F 1 69  ? -1.47622  0.46646   100.73129 1.000 86.28843  ? 49  ARG F CD  1 
ATOM   6604 N  NE  . ARG F 1 69  ? -1.84780  0.93604   102.06019 1.000 85.90103  ? 49  ARG F NE  1 
ATOM   6605 C  CZ  . ARG F 1 69  ? -0.98197  1.34631   102.97662 1.000 91.44974  ? 49  ARG F CZ  1 
ATOM   6606 N  NH1 . ARG F 1 69  ? 0.31988   1.35716   102.74126 1.000 83.30408  ? 49  ARG F NH1 1 
ATOM   6607 N  NH2 . ARG F 1 69  ? -1.43326  1.75407   104.15942 1.000 98.94448  ? 49  ARG F NH2 1 
ATOM   6608 N  N   . MET F 1 70  ? -1.13496  -4.52393  100.87477 1.000 76.93108  ? 50  MET F N   1 
ATOM   6609 C  CA  . MET F 1 70  ? -2.14278  -5.41339  101.44481 1.000 73.02179  ? 50  MET F CA  1 
ATOM   6610 C  C   . MET F 1 70  ? -3.29948  -4.63761  102.05996 1.000 75.26078  ? 50  MET F C   1 
ATOM   6611 O  O   . MET F 1 70  ? -4.42282  -5.15100  102.12586 1.000 65.35175  ? 50  MET F O   1 
ATOM   6612 C  CB  . MET F 1 70  ? -1.50665  -6.32998  102.48935 1.000 71.68475  ? 50  MET F CB  1 
ATOM   6613 N  N   . GLU F 1 71  ? -3.04772  -3.40847  102.51494 1.000 82.46012  ? 51  GLU F N   1 
ATOM   6614 C  CA  . GLU F 1 71  ? -4.11609  -2.60013  103.09282 1.000 83.26651  ? 51  GLU F CA  1 
ATOM   6615 C  C   . GLU F 1 71  ? -5.14670  -2.21621  102.03811 1.000 73.20197  ? 51  GLU F C   1 
ATOM   6616 O  O   . GLU F 1 71  ? -6.35568  -2.24593  102.30236 1.000 64.24589  ? 51  GLU F O   1 
ATOM   6617 C  CB  . GLU F 1 71  ? -3.52855  -1.35342  103.75826 1.000 88.80263  ? 51  GLU F CB  1 
ATOM   6618 C  CG  . GLU F 1 71  ? -2.71741  -1.62111  105.02969 1.000 96.60503  ? 51  GLU F CG  1 
ATOM   6619 C  CD  . GLU F 1 71  ? -1.33027  -2.19161  104.76034 1.000 100.87019 ? 51  GLU F CD  1 
ATOM   6620 O  OE1 . GLU F 1 71  ? -1.00965  -2.48133  103.58827 1.000 93.98387  ? 51  GLU F OE1 1 
ATOM   6621 O  OE2 . GLU F 1 71  ? -0.55587  -2.34903  105.72836 1.000 102.80603 ? 51  GLU F OE2 1 
ATOM   6622 N  N   . THR F 1 72  ? -4.68876  -1.85307  100.83669 1.000 68.46974  ? 52  THR F N   1 
ATOM   6623 C  CA  . THR F 1 72  ? -5.62149  -1.57780  99.74862  1.000 73.76678  ? 52  THR F CA  1 
ATOM   6624 C  C   . THR F 1 72  ? -6.43342  -2.81803  99.39623  1.000 63.06226  ? 52  THR F C   1 
ATOM   6625 O  O   . THR F 1 72  ? -7.63120  -2.72080  99.10896  1.000 56.20754  ? 52  THR F O   1 
ATOM   6626 C  CB  . THR F 1 72  ? -4.87111  -1.05842  98.52039  1.000 67.22927  ? 52  THR F CB  1 
ATOM   6627 O  OG1 . THR F 1 72  ? -3.62861  -1.75853  98.38218  1.000 80.43288  ? 52  THR F OG1 1 
ATOM   6628 C  CG2 . THR F 1 72  ? -4.60335  0.43684   98.64246  1.000 45.40531  ? 52  THR F CG2 1 
ATOM   6629 N  N   . THR F 1 73  ? -5.80053  -3.99423  99.42002  1.000 64.10948  ? 53  THR F N   1 
ATOM   6630 C  CA  . THR F 1 73  ? -6.52910  -5.23618  99.17413  1.000 62.36381  ? 53  THR F CA  1 
ATOM   6631 C  C   . THR F 1 73  ? -7.61375  -5.44938  100.22340 1.000 65.16875  ? 53  THR F C   1 
ATOM   6632 O  O   . THR F 1 73  ? -8.76113  -5.77616  99.89312  1.000 55.58654  ? 53  THR F O   1 
ATOM   6633 C  CB  . THR F 1 73  ? -5.56076  -6.42228  99.15759  1.000 65.26687  ? 53  THR F CB  1 
ATOM   6634 O  OG1 . THR F 1 73  ? -4.56347  -6.21828  98.14852  1.000 67.84000  ? 53  THR F OG1 1 
ATOM   6635 C  CG2 . THR F 1 73  ? -6.30419  -7.72092  98.86843  1.000 57.99000  ? 53  THR F CG2 1 
ATOM   6636 N  N   . GLU F 1 74  ? -7.26006  -5.27911  101.50074 1.000 70.20911  ? 54  GLU F N   1 
ATOM   6637 C  CA  . GLU F 1 74  ? -8.24101  -5.42800  102.57114 1.000 63.51650  ? 54  GLU F CA  1 
ATOM   6638 C  C   . GLU F 1 74  ? -9.40035  -4.45630  102.39319 1.000 58.20020  ? 54  GLU F C   1 
ATOM   6639 O  O   . GLU F 1 74  ? -10.56718 -4.83154  102.56047 1.000 56.82142  ? 54  GLU F O   1 
ATOM   6640 C  CB  . GLU F 1 74  ? -7.57081  -5.21664  103.92821 1.000 71.56348  ? 54  GLU F CB  1 
ATOM   6641 C  CG  . GLU F 1 74  ? -8.48380  -5.45456  105.11927 1.000 73.95983  ? 54  GLU F CG  1 
ATOM   6642 C  CD  . GLU F 1 74  ? -8.27594  -4.43370  106.22058 1.000 79.80925  ? 54  GLU F CD  1 
ATOM   6643 O  OE1 . GLU F 1 74  ? -8.73172  -3.28191  106.05684 1.000 68.29612  ? 54  GLU F OE1 1 
ATOM   6644 O  OE2 . GLU F 1 74  ? -7.64774  -4.77864  107.24385 1.000 85.65163  ? 54  GLU F OE2 1 
ATOM   6645 N  N   . HIS F 1 75  ? -9.09898  -3.20541  102.03516 1.000 57.33277  ? 55  HIS F N   1 
ATOM   6646 C  CA  . HIS F 1 75  ? -10.15659 -2.21447  101.85681 1.000 57.22843  ? 55  HIS F CA  1 
ATOM   6647 C  C   . HIS F 1 75  ? -11.06107 -2.56474  100.68046 1.000 59.28161  ? 55  HIS F C   1 
ATOM   6648 O  O   . HIS F 1 75  ? -12.29013 -2.48018  100.79178 1.000 54.79186  ? 55  HIS F O   1 
ATOM   6649 C  CB  . HIS F 1 75  ? -9.55419  -0.82240  101.66836 1.000 58.94915  ? 55  HIS F CB  1 
ATOM   6650 C  CG  . HIS F 1 75  ? -10.56125 0.22281   101.30111 1.000 59.27694  ? 55  HIS F CG  1 
ATOM   6651 N  ND1 . HIS F 1 75  ? -11.66821 0.49418   102.07651 1.000 59.33484  ? 55  HIS F ND1 1 
ATOM   6652 C  CD2 . HIS F 1 75  ? -10.63396 1.05710   100.23694 1.000 60.52472  ? 55  HIS F CD2 1 
ATOM   6653 C  CE1 . HIS F 1 75  ? -12.37697 1.45353   101.50853 1.000 62.85801  ? 55  HIS F CE1 1 
ATOM   6654 N  NE2 . HIS F 1 75  ? -11.77131 1.81257   100.39090 1.000 68.32275  ? 55  HIS F NE2 1 
ATOM   6655 N  N   . ARG F 1 76  ? -10.47627 -2.95809  99.54516  1.000 59.18448  ? 56  ARG F N   1 
ATOM   6656 C  CA  . ARG F 1 76  ? -11.28757 -3.27423  98.37347  1.000 54.46681  ? 56  ARG F CA  1 
ATOM   6657 C  C   . ARG F 1 76  ? -12.16101 -4.49792  98.61744  1.000 54.62032  ? 56  ARG F C   1 
ATOM   6658 O  O   . ARG F 1 76  ? -13.34729 -4.49581  98.26866  1.000 52.44939  ? 56  ARG F O   1 
ATOM   6659 C  CB  . ARG F 1 76  ? -10.39895 -3.49117  97.14819  1.000 50.55073  ? 56  ARG F CB  1 
ATOM   6660 C  CG  . ARG F 1 76  ? -9.60607  -2.26962  96.71132  1.000 46.87555  ? 56  ARG F CG  1 
ATOM   6661 C  CD  . ARG F 1 76  ? -10.49016 -1.03995  96.57275  1.000 49.34556  ? 56  ARG F CD  1 
ATOM   6662 N  NE  . ARG F 1 76  ? -9.72918  0.11788   96.12025  1.000 47.96110  ? 56  ARG F NE  1 
ATOM   6663 C  CZ  . ARG F 1 76  ? -10.19968 1.35661   96.08484  1.000 48.92443  ? 56  ARG F CZ  1 
ATOM   6664 N  NH1 . ARG F 1 76  ? -11.42522 1.64208   96.49255  1.000 45.44418  ? 56  ARG F NH1 1 
ATOM   6665 N  NH2 . ARG F 1 76  ? -9.42010  2.33393   95.63087  1.000 46.02280  ? 56  ARG F NH2 1 
ATOM   6666 N  N   . VAL F 1 77  ? -11.59834 -5.55294  99.21379  1.000 51.77894  ? 57  VAL F N   1 
ATOM   6667 C  CA  . VAL F 1 77  ? -12.38979 -6.75101  99.47931  1.000 54.72683  ? 57  VAL F CA  1 
ATOM   6668 C  C   . VAL F 1 77  ? -13.47213 -6.45630  100.51103 1.000 57.06687  ? 57  VAL F C   1 
ATOM   6669 O  O   . VAL F 1 77  ? -14.59629 -6.96493  100.41587 1.000 55.73210  ? 57  VAL F O   1 
ATOM   6670 C  CB  . VAL F 1 77  ? -11.47825 -7.91058  99.92441  1.000 61.16642  ? 57  VAL F CB  1 
ATOM   6671 C  CG1 . VAL F 1 77  ? -12.30035 -9.15845  100.20475 1.000 53.73475  ? 57  VAL F CG1 1 
ATOM   6672 C  CG2 . VAL F 1 77  ? -10.42340 -8.20142  98.86437  1.000 58.52233  ? 57  VAL F CG2 1 
ATOM   6673 N  N   . ARG F 1 78  ? -13.15835 -5.61587  101.50099 1.000 66.99604  ? 58  ARG F N   1 
ATOM   6674 C  CA  . ARG F 1 78  ? -14.12786 -5.28187  102.53839 1.000 62.09174  ? 58  ARG F CA  1 
ATOM   6675 C  C   . ARG F 1 78  ? -15.30121 -4.48429  101.98041 1.000 56.63695  ? 58  ARG F C   1 
ATOM   6676 O  O   . ARG F 1 78  ? -16.42751 -4.61452  102.47362 1.000 56.43102  ? 58  ARG F O   1 
ATOM   6677 C  CB  . ARG F 1 78  ? -13.42766 -4.50666  103.65480 1.000 59.61914  ? 58  ARG F CB  1 
ATOM   6678 C  CG  . ARG F 1 78  ? -14.08251 -4.59426  105.01888 1.000 59.28607  ? 58  ARG F CG  1 
ATOM   6679 C  CD  . ARG F 1 78  ? -13.10678 -4.12304  106.08584 1.000 63.82177  ? 58  ARG F CD  1 
ATOM   6680 N  NE  . ARG F 1 78  ? -13.70287 -4.05758  107.41465 1.000 63.52546  ? 58  ARG F NE  1 
ATOM   6681 C  CZ  . ARG F 1 78  ? -13.03059 -3.75729  108.51777 1.000 62.02437  ? 58  ARG F CZ  1 
ATOM   6682 N  NH1 . ARG F 1 78  ? -11.73229 -3.50398  108.48821 1.000 56.60290  ? 58  ARG F NH1 1 
ATOM   6683 N  NH2 . ARG F 1 78  ? -13.67619 -3.71133  109.67948 1.000 54.99689  ? 58  ARG F NH2 1 
ATOM   6684 N  N   . SER F 1 79  ? -15.06306 -3.66391  100.95766 1.000 58.85027  ? 59  SER F N   1 
ATOM   6685 C  CA  . SER F 1 79  ? -16.11850 -2.87474  100.33520 1.000 50.08962  ? 59  SER F CA  1 
ATOM   6686 C  C   . SER F 1 79  ? -16.91407 -3.65595  99.29868  1.000 55.68046  ? 59  SER F C   1 
ATOM   6687 O  O   . SER F 1 79  ? -17.86292 -3.10565  98.72955  1.000 56.19601  ? 59  SER F O   1 
ATOM   6688 C  CB  . SER F 1 79  ? -15.52539 -1.62229  99.68343  1.000 59.06107  ? 59  SER F CB  1 
ATOM   6689 O  OG  . SER F 1 79  ? -14.85455 -0.81650  100.63528 1.000 52.34717  ? 59  SER F OG  1 
ATOM   6690 N  N   . GLY F 1 80  ? -16.55971 -4.91243  99.04182  1.000 66.24539  ? 60  GLY F N   1 
ATOM   6691 C  CA  . GLY F 1 80  ? -17.23699 -5.67892  98.01391  1.000 52.40622  ? 60  GLY F CA  1 
ATOM   6692 C  C   . GLY F 1 80  ? -16.93629 -5.22128  96.60510  1.000 57.11282  ? 60  GLY F C   1 
ATOM   6693 O  O   . GLY F 1 80  ? -17.78485 -5.36417  95.71953  1.000 56.57379  ? 60  GLY F O   1 
ATOM   6694 N  N   . SER F 1 81  ? -15.74325 -4.67215  96.37309  1.000 50.78565  ? 61  SER F N   1 
ATOM   6695 C  CA  . SER F 1 81  ? -15.35964 -4.14360  95.07190  1.000 55.23974  ? 61  SER F CA  1 
ATOM   6696 C  C   . SER F 1 81  ? -14.54298 -5.12072  94.23814  1.000 50.46095  ? 61  SER F C   1 
ATOM   6697 O  O   . SER F 1 81  ? -14.24231 -4.81643  93.07926  1.000 49.41822  ? 61  SER F O   1 
ATOM   6698 C  CB  . SER F 1 81  ? -14.56131 -2.84497  95.24203  1.000 51.57732  ? 61  SER F CB  1 
ATOM   6699 O  OG  . SER F 1 81  ? -15.32986 -1.85267  95.89882  1.000 65.28263  ? 61  SER F OG  1 
ATOM   6700 N  N   . VAL F 1 82  ? -14.17495 -6.27280  94.78879  1.000 53.80327  ? 62  VAL F N   1 
ATOM   6701 C  CA  . VAL F 1 82  ? -13.33399 -7.24191  94.09652  1.000 51.91330  ? 62  VAL F CA  1 
ATOM   6702 C  C   . VAL F 1 82  ? -14.21519 -8.38597  93.61889  1.000 55.31149  ? 62  VAL F C   1 
ATOM   6703 O  O   . VAL F 1 82  ? -14.79093 -9.12054  94.43109  1.000 49.86032  ? 62  VAL F O   1 
ATOM   6704 C  CB  . VAL F 1 82  ? -12.20505 -7.75418  95.00262  1.000 51.40737  ? 62  VAL F CB  1 
ATOM   6705 C  CG1 . VAL F 1 82  ? -11.10565 -8.39883  94.17173  1.000 47.39141  ? 62  VAL F CG1 1 
ATOM   6706 C  CG2 . VAL F 1 82  ? -11.65364 -6.61980  95.84561  1.000 51.19864  ? 62  VAL F CG2 1 
ATOM   6707 N  N   . HIS F 1 83  ? -14.31649 -8.54052  92.30206  1.000 58.01059  ? 63  HIS F N   1 
ATOM   6708 C  CA  . HIS F 1 83  ? -15.08867 -9.61536  91.69339  1.000 51.85766  ? 63  HIS F CA  1 
ATOM   6709 C  C   . HIS F 1 83  ? -14.13633 -10.70169 91.21553  1.000 47.41190  ? 63  HIS F C   1 
ATOM   6710 O  O   . HIS F 1 83  ? -13.20123 -10.41956 90.45504  1.000 50.48370  ? 63  HIS F O   1 
ATOM   6711 C  CB  . HIS F 1 83  ? -15.93183 -9.09226  90.53012  1.000 43.65047  ? 63  HIS F CB  1 
ATOM   6712 C  CG  . HIS F 1 83  ? -16.90190 -8.02469  90.92217  1.000 46.51302  ? 63  HIS F CG  1 
ATOM   6713 N  ND1 . HIS F 1 83  ? -16.50394 -6.80184  91.41812  1.000 53.16148  ? 63  HIS F ND1 1 
ATOM   6714 C  CD2 . HIS F 1 83  ? -18.25475 -8.00143  90.90205  1.000 53.13300  ? 63  HIS F CD2 1 
ATOM   6715 C  CE1 . HIS F 1 83  ? -17.57054 -6.06982  91.68332  1.000 49.04179  ? 63  HIS F CE1 1 
ATOM   6716 N  NE2 . HIS F 1 83  ? -18.64539 -6.77459  91.37907  1.000 46.26027  ? 63  HIS F NE2 1 
ATOM   6717 N  N   . LEU F 1 84  ? -14.37655 -11.93673 91.66294  1.000 50.67164  ? 64  LEU F N   1 
ATOM   6718 C  CA  . LEU F 1 84  ? -13.47414 -13.05325 91.41821  1.000 54.76828  ? 64  LEU F CA  1 
ATOM   6719 C  C   . LEU F 1 84  ? -14.20190 -14.16673 90.67667  1.000 49.73338  ? 64  LEU F C   1 
ATOM   6720 O  O   . LEU F 1 84  ? -15.34455 -14.50285 91.00438  1.000 47.63587  ? 64  LEU F O   1 
ATOM   6721 C  CB  . LEU F 1 84  ? -12.89404 -13.58481 92.73280  1.000 57.80866  ? 64  LEU F CB  1 
ATOM   6722 C  CG  . LEU F 1 84  ? -11.76002 -14.60994 92.64747  1.000 61.75488  ? 64  LEU F CG  1 
ATOM   6723 C  CD1 . LEU F 1 84  ? -10.69145 -14.30723 93.68176  1.000 61.92154  ? 64  LEU F CD1 1 
ATOM   6724 C  CD2 . LEU F 1 84  ? -12.29722 -16.01192 92.84281  1.000 64.22493  ? 64  LEU F CD2 1 
ATOM   6725 N  N   . LEU F 1 85  ? -13.52317 -14.74186 89.68619  1.000 54.83682  ? 65  LEU F N   1 
ATOM   6726 C  CA  . LEU F 1 85  ? -14.05429 -15.78772 88.82260  1.000 60.88508  ? 65  LEU F CA  1 
ATOM   6727 C  C   . LEU F 1 85  ? -13.30936 -17.08589 89.10196  1.000 59.08811  ? 65  LEU F C   1 
ATOM   6728 O  O   . LEU F 1 85  ? -12.08826 -17.15867 88.90516  1.000 55.16370  ? 65  LEU F O   1 
ATOM   6729 C  CB  . LEU F 1 85  ? -13.91090 -15.39298 87.35291  1.000 59.43148  ? 65  LEU F CB  1 
ATOM   6730 C  CG  . LEU F 1 85  ? -14.15625 -16.45857 86.28377  1.000 55.70288  ? 65  LEU F CG  1 
ATOM   6731 C  CD1 . LEU F 1 85  ? -15.60779 -16.91329 86.28671  1.000 52.85207  ? 65  LEU F CD1 1 
ATOM   6732 C  CD2 . LEU F 1 85  ? -13.75560 -15.92378 84.91806  1.000 57.32301  ? 65  LEU F CD2 1 
ATOM   6733 N  N   . ARG F 1 86  ? -14.04859 -18.09548 89.55937  1.000 55.14805  ? 66  ARG F N   1 
ATOM   6734 C  CA  . ARG F 1 86  ? -13.53832 -19.42509 89.85249  1.000 73.88420  ? 66  ARG F CA  1 
ATOM   6735 C  C   . ARG F 1 86  ? -13.93260 -20.40295 88.75547  1.000 65.85158  ? 66  ARG F C   1 
ATOM   6736 O  O   . ARG F 1 86  ? -14.97761 -20.25801 88.11229  1.000 57.80539  ? 66  ARG F O   1 
ATOM   6737 C  CB  . ARG F 1 86  ? -14.08072 -19.95387 91.18559  1.000 73.80132  ? 66  ARG F CB  1 
ATOM   6738 C  CG  . ARG F 1 86  ? -13.54275 -19.27215 92.41748  1.000 76.86285  ? 66  ARG F CG  1 
ATOM   6739 C  CD  . ARG F 1 86  ? -14.14743 -19.88611 93.66851  1.000 76.83197  ? 66  ARG F CD  1 
ATOM   6740 N  NE  . ARG F 1 86  ? -13.94167 -19.03792 94.83534  1.000 81.31102  ? 66  ARG F NE  1 
ATOM   6741 C  CZ  . ARG F 1 86  ? -12.85882 -19.06547 95.59889  1.000 76.51460  ? 66  ARG F CZ  1 
ATOM   6742 N  NH1 . ARG F 1 86  ? -11.86532 -19.90448 95.35857  1.000 75.77458  ? 66  ARG F NH1 1 
ATOM   6743 N  NH2 . ARG F 1 86  ? -12.76909 -18.22759 96.62729  1.000 72.99162  ? 66  ARG F NH2 1 
ATOM   6744 N  N   . HIS F 1 87  ? -13.08891 -21.41558 88.57023  1.000 74.09524  ? 67  HIS F N   1 
ATOM   6745 C  CA  . HIS F 1 87  ? -13.36928 -22.53693 87.68295  1.000 79.72222  ? 67  HIS F CA  1 
ATOM   6746 C  C   . HIS F 1 87  ? -13.17202 -23.82351 88.46827  1.000 78.79652  ? 67  HIS F C   1 
ATOM   6747 O  O   . HIS F 1 87  ? -12.05122 -24.12522 88.89387  1.000 73.09948  ? 67  HIS F O   1 
ATOM   6748 C  CB  . HIS F 1 87  ? -12.46591 -22.52016 86.44878  1.000 78.72104  ? 67  HIS F CB  1 
ATOM   6749 C  CG  . HIS F 1 87  ? -12.71670 -23.65798 85.50872  1.000 76.38487  ? 67  HIS F CG  1 
ATOM   6750 N  ND1 . HIS F 1 87  ? -13.89482 -23.79836 84.80639  1.000 77.89858  ? 67  HIS F ND1 1 
ATOM   6751 C  CD2 . HIS F 1 87  ? -11.94360 -24.71280 85.15959  1.000 72.87474  ? 67  HIS F CD2 1 
ATOM   6752 C  CE1 . HIS F 1 87  ? -13.83515 -24.88797 84.06199  1.000 74.76763  ? 67  HIS F CE1 1 
ATOM   6753 N  NE2 . HIS F 1 87  ? -12.66132 -25.46091 84.25780  1.000 79.70121  ? 67  HIS F NE2 1 
ATOM   6754 N  N   . ASP F 1 88  ? -14.25851 -24.57473 88.65875  1.000 82.38671  ? 68  ASP F N   1 
ATOM   6755 C  CA  . ASP F 1 88  ? -14.23615 -25.80676 89.44884  1.000 88.35126  ? 68  ASP F CA  1 
ATOM   6756 C  C   . ASP F 1 88  ? -13.66546 -25.55882 90.84134  1.000 84.04254  ? 68  ASP F C   1 
ATOM   6757 O  O   . ASP F 1 88  ? -12.92135 -26.37377 91.38863  1.000 78.58452  ? 68  ASP F O   1 
ATOM   6758 C  CB  . ASP F 1 88  ? -13.45554 -26.91363 88.73385  1.000 86.89422  ? 68  ASP F CB  1 
ATOM   6759 C  CG  . ASP F 1 88  ? -14.14539 -27.39580 87.46892  1.000 86.58195  ? 68  ASP F CG  1 
ATOM   6760 O  OD1 . ASP F 1 88  ? -15.38204 -27.25494 87.37083  1.000 84.18823  ? 68  ASP F OD1 1 
ATOM   6761 O  OD2 . ASP F 1 88  ? -13.45059 -27.92734 86.57677  1.000 84.76045  ? 68  ASP F OD2 1 
ATOM   6762 N  N   . GLY F 1 89  ? -14.02165 -24.42124 91.42303  1.000 79.91621  ? 69  GLY F N   1 
ATOM   6763 C  CA  . GLY F 1 89  ? -13.57817 -24.09523 92.76359  1.000 72.27564  ? 69  GLY F CA  1 
ATOM   6764 C  C   . GLY F 1 89  ? -12.26138 -23.34914 92.76277  1.000 73.00689  ? 69  GLY F C   1 
ATOM   6765 O  O   . GLY F 1 89  ? -12.02169 -22.49145 93.61583  1.000 81.51999  ? 69  GLY F O   1 
ATOM   6766 N  N   . ARG F 1 90  ? -11.39332 -23.66980 91.80583  1.000 71.61142  ? 70  ARG F N   1 
ATOM   6767 C  CA  . ARG F 1 90  ? -10.09909 -23.00088 91.72526  1.000 71.11152  ? 70  ARG F CA  1 
ATOM   6768 C  C   . ARG F 1 90  ? -10.26784 -21.61371 91.11364  1.000 78.85345  ? 70  ARG F C   1 
ATOM   6769 O  O   . ARG F 1 90  ? -10.89897 -21.47848 90.06046  1.000 82.45440  ? 70  ARG F O   1 
ATOM   6770 C  CB  . ARG F 1 90  ? -9.10974  -23.82228 90.90552  1.000 78.29369  ? 70  ARG F CB  1 
ATOM   6771 C  CG  . ARG F 1 90  ? -7.86988  -23.05230 90.49908  1.000 85.24193  ? 70  ARG F CG  1 
ATOM   6772 C  CD  . ARG F 1 90  ? -6.61845  -23.92261 90.49361  1.000 84.30089  ? 70  ARG F CD  1 
ATOM   6773 N  NE  . ARG F 1 90  ? -6.14808  -24.21167 91.84375  1.000 96.11625  ? 70  ARG F NE  1 
ATOM   6774 C  CZ  . ARG F 1 90  ? -4.95198  -24.70676 92.13412  1.000 98.81141  ? 70  ARG F CZ  1 
ATOM   6775 N  NH1 . ARG F 1 90  ? -4.06678  -24.97841 91.18856  1.000 97.25257  ? 70  ARG F NH1 1 
ATOM   6776 N  NH2 . ARG F 1 90  ? -4.63371  -24.92987 93.40617  1.000 92.13177  ? 70  ARG F NH2 1 
ATOM   6777 N  N   . PRO F 1 91  ? -9.73099  -20.56915 91.74217  1.000 82.25431  ? 71  PRO F N   1 
ATOM   6778 C  CA  . PRO F 1 91  ? -9.92376  -19.20977 91.21941  1.000 75.57359  ? 71  PRO F CA  1 
ATOM   6779 C  C   . PRO F 1 91  ? -9.12009  -19.00047 89.94398  1.000 72.23147  ? 71  PRO F C   1 
ATOM   6780 O  O   . PRO F 1 91  ? -7.92478  -19.29820 89.89296  1.000 71.92123  ? 71  PRO F O   1 
ATOM   6781 C  CB  . PRO F 1 91  ? -9.42163  -18.31578 92.36114  1.000 75.08572  ? 71  PRO F CB  1 
ATOM   6782 C  CG  . PRO F 1 91  ? -9.26072  -19.22706 93.55524  1.000 65.56453  ? 71  PRO F CG  1 
ATOM   6783 C  CD  . PRO F 1 91  ? -8.97434  -20.57580 93.00336  1.000 72.90304  ? 71  PRO F CD  1 
ATOM   6784 N  N   . ALA F 1 92  ? -9.78593  -18.47601 88.91611  1.000 70.07735  ? 72  ALA F N   1 
ATOM   6785 C  CA  . ALA F 1 92  ? -9.19173  -18.28698 87.59732  1.000 69.37077  ? 72  ALA F CA  1 
ATOM   6786 C  C   . ALA F 1 92  ? -8.86011  -16.83982 87.27359  1.000 67.68911  ? 72  ALA F C   1 
ATOM   6787 O  O   . ALA F 1 92  ? -7.83150  -16.57530 86.64694  1.000 67.83827  ? 72  ALA F O   1 
ATOM   6788 C  CB  . ALA F 1 92  ? -10.13227 -18.83159 86.51969  1.000 71.24247  ? 72  ALA F CB  1 
ATOM   6789 N  N   . GLY F 1 93  ? -9.70063  -15.89243 87.68202  1.000 70.91058  ? 73  GLY F N   1 
ATOM   6790 C  CA  . GLY F 1 93  ? -9.42247  -14.49770 87.38908  1.000 65.89440  ? 73  GLY F CA  1 
ATOM   6791 C  C   . GLY F 1 93  ? -10.11199 -13.59866 88.38859  1.000 62.41568  ? 73  GLY F C   1 
ATOM   6792 O  O   . GLY F 1 93  ? -10.79902 -14.06731 89.29640  1.000 62.54255  ? 73  GLY F O   1 
ATOM   6793 N  N   . MET F 1 94  ? -9.93132  -12.29013 88.20661  1.000 55.53001  ? 74  MET F N   1 
ATOM   6794 C  CA  . MET F 1 94  ? -10.59049 -11.30870 89.06482  1.000 59.47511  ? 74  MET F CA  1 
ATOM   6795 C  C   . MET F 1 94  ? -10.32490 -9.90537  88.53918  1.000 58.42910  ? 74  MET F C   1 
ATOM   6796 O  O   . MET F 1 94  ? -9.49057  -9.69285  87.65508  1.000 55.13033  ? 74  MET F O   1 
ATOM   6797 C  CB  . MET F 1 94  ? -10.11931 -11.41053 90.51745  1.000 48.88120  ? 74  MET F CB  1 
ATOM   6798 C  CG  . MET F 1 94  ? -8.66465  -11.04378 90.70192  1.000 50.32835  ? 74  MET F CG  1 
ATOM   6799 S  SD  . MET F 1 94  ? -8.23533  -10.83497 92.43517  1.000 59.05661  ? 74  MET F SD  1 
ATOM   6800 C  CE  . MET F 1 94  ? -6.45926  -10.66639 92.30207  1.000 60.24380  ? 74  MET F CE  1 
ATOM   6801 N  N   . PHE F 1 95  ? -11.05012 -8.94900  89.11510  1.000 60.31731  ? 75  PHE F N   1 
ATOM   6802 C  CA  . PHE F 1 95  ? -10.82022 -7.52908  88.87548  1.000 55.49840  ? 75  PHE F CA  1 
ATOM   6803 C  C   . PHE F 1 95  ? -11.36668 -6.75104  90.06468  1.000 55.99876  ? 75  PHE F C   1 
ATOM   6804 O  O   . PHE F 1 95  ? -12.08146 -7.29628  90.91022  1.000 55.74756  ? 75  PHE F O   1 
ATOM   6805 C  CB  . PHE F 1 95  ? -11.45693 -7.06375  87.55924  1.000 48.88863  ? 75  PHE F CB  1 
ATOM   6806 C  CG  . PHE F 1 95  ? -12.95543 -7.19021  87.52372  1.000 51.29632  ? 75  PHE F CG  1 
ATOM   6807 C  CD1 . PHE F 1 95  ? -13.76372 -6.13724  87.92559  1.000 41.28246  ? 75  PHE F CD1 1 
ATOM   6808 C  CD2 . PHE F 1 95  ? -13.55603 -8.35699  87.07694  1.000 43.33636  ? 75  PHE F CD2 1 
ATOM   6809 C  CE1 . PHE F 1 95  ? -15.13980 -6.24998  87.89234  1.000 47.67792  ? 75  PHE F CE1 1 
ATOM   6810 C  CE2 . PHE F 1 95  ? -14.93344 -8.47399  87.03992  1.000 38.65354  ? 75  PHE F CE2 1 
ATOM   6811 C  CZ  . PHE F 1 95  ? -15.72495 -7.42083  87.44878  1.000 42.64475  ? 75  PHE F CZ  1 
ATOM   6812 N  N   . THR F 1 96  ? -11.02111 -5.46412  90.12196  1.000 55.17733  ? 76  THR F N   1 
ATOM   6813 C  CA  . THR F 1 96  ? -11.50287 -4.55871  91.15356  1.000 49.53471  ? 76  THR F CA  1 
ATOM   6814 C  C   . THR F 1 96  ? -12.23309 -3.40888  90.47866  1.000 45.24523  ? 76  THR F C   1 
ATOM   6815 O  O   . THR F 1 96  ? -11.69314 -2.77897  89.56341  1.000 46.92987  ? 76  THR F O   1 
ATOM   6816 C  CB  . THR F 1 96  ? -10.34856 -4.02926  92.01268  1.000 58.78692  ? 76  THR F CB  1 
ATOM   6817 O  OG1 . THR F 1 96  ? -9.72095  -5.11624  92.70464  1.000 55.17526  ? 76  THR F OG1 1 
ATOM   6818 C  CG2 . THR F 1 96  ? -10.85743 -3.01428  93.03269  1.000 51.66328  ? 76  THR F CG2 1 
ATOM   6819 N  N   . LEU F 1 97  ? -13.45929 -3.14892  90.92080  1.000 40.29574  ? 77  LEU F N   1 
ATOM   6820 C  CA  . LEU F 1 97  ? -14.31144 -2.11984  90.34066  1.000 47.71593  ? 77  LEU F CA  1 
ATOM   6821 C  C   . LEU F 1 97  ? -14.69808 -1.14404  91.44107  1.000 52.41736  ? 77  LEU F C   1 
ATOM   6822 O  O   . LEU F 1 97  ? -15.37229 -1.52854  92.40326  1.000 53.52039  ? 77  LEU F O   1 
ATOM   6823 C  CB  . LEU F 1 97  ? -15.55264 -2.74292  89.70025  1.000 38.48551  ? 77  LEU F CB  1 
ATOM   6824 C  CG  . LEU F 1 97  ? -16.48471 -1.79561  88.95063  1.000 42.55674  ? 77  LEU F CG  1 
ATOM   6825 C  CD1 . LEU F 1 97  ? -15.75147 -1.13617  87.79511  1.000 43.49035  ? 77  LEU F CD1 1 
ATOM   6826 C  CD2 . LEU F 1 97  ? -17.71598 -2.54050  88.45805  1.000 42.17587  ? 77  LEU F CD2 1 
ATOM   6827 N  N   . THR F 1 98  ? -14.27207 0.11168   91.30389  1.000 40.64228  ? 78  THR F N   1 
ATOM   6828 C  CA  . THR F 1 98  ? -14.45632 1.09667   92.36172  1.000 39.81367  ? 78  THR F CA  1 
ATOM   6829 C  C   . THR F 1 98  ? -15.08639 2.37160   91.81474  1.000 45.18520  ? 78  THR F C   1 
ATOM   6830 O  O   . THR F 1 98  ? -15.06965 2.63666   90.61089  1.000 37.33874  ? 78  THR F O   1 
ATOM   6831 C  CB  . THR F 1 98  ? -13.12471 1.43698   93.05364  1.000 48.40045  ? 78  THR F CB  1 
ATOM   6832 O  OG1 . THR F 1 98  ? -12.18314 1.91615   92.08524  1.000 46.19119  ? 78  THR F OG1 1 
ATOM   6833 C  CG2 . THR F 1 98  ? -12.55219 0.20827   93.74709  1.000 42.81193  ? 78  THR F CG2 1 
ATOM   6834 N  N   . TRP F 1 99  ? -15.66079 3.16063   92.72629  1.000 45.92320  ? 79  TRP F N   1 
ATOM   6835 C  CA  . TRP F 1 99  ? -16.16651 4.48464   92.38370  1.000 44.87280  ? 79  TRP F CA  1 
ATOM   6836 C  C   . TRP F 1 99  ? -15.10046 5.56631   92.48593  1.000 43.82893  ? 79  TRP F C   1 
ATOM   6837 O  O   . TRP F 1 99  ? -15.23829 6.61761   91.84864  1.000 43.54160  ? 79  TRP F O   1 
ATOM   6838 C  CB  . TRP F 1 99  ? -17.34636 4.86377   93.28616  1.000 46.10555  ? 79  TRP F CB  1 
ATOM   6839 C  CG  . TRP F 1 99  ? -18.60306 4.09022   93.01800  1.000 44.57800  ? 79  TRP F CG  1 
ATOM   6840 C  CD1 . TRP F 1 99  ? -19.07759 3.02331   93.72595  1.000 42.77628  ? 79  TRP F CD1 1 
ATOM   6841 C  CD2 . TRP F 1 99  ? -19.55089 4.32879   91.96970  1.000 48.21210  ? 79  TRP F CD2 1 
ATOM   6842 N  NE1 . TRP F 1 99  ? -20.26055 2.58235   93.18183  1.000 49.07468  ? 79  TRP F NE1 1 
ATOM   6843 C  CE2 . TRP F 1 99  ? -20.57214 3.36636   92.10245  1.000 45.70859  ? 79  TRP F CE2 1 
ATOM   6844 C  CE3 . TRP F 1 99  ? -19.63367 5.26065   90.93086  1.000 45.29963  ? 79  TRP F CE3 1 
ATOM   6845 C  CZ2 . TRP F 1 99  ? -21.66146 3.30933   91.23621  1.000 47.10512  ? 79  TRP F CZ2 1 
ATOM   6846 C  CZ3 . TRP F 1 99  ? -20.71603 5.20273   90.07243  1.000 52.75645  ? 79  TRP F CZ3 1 
ATOM   6847 C  CH2 . TRP F 1 99  ? -21.71542 4.23370   90.22991  1.000 53.42212  ? 79  TRP F CH2 1 
ATOM   6848 N  N   . ASP F 1 100 ? -14.03931 5.33352   93.28028  1.000 41.47183  ? 80  ASP F N   1 
ATOM   6849 C  CA  . ASP F 1 100 ? -12.92381 6.24088   93.48806  1.000 46.84337  ? 80  ASP F CA  1 
ATOM   6850 C  C   . ASP F 1 100 ? -11.75463 5.87878   92.57922  1.000 49.34886  ? 80  ASP F C   1 
ATOM   6851 O  O   . ASP F 1 100 ? -11.54139 4.70291   92.26740  1.000 50.12151  ? 80  ASP F O   1 
ATOM   6852 C  CB  . ASP F 1 100 ? -12.45632 6.20008   94.94606  1.000 39.30245  ? 80  ASP F CB  1 
ATOM   6853 C  CG  . ASP F 1 100 ? -12.16736 4.79267   95.42700  1.000 45.15199  ? 80  ASP F CG  1 
ATOM   6854 O  OD1 . ASP F 1 100 ? -13.02310 3.90555   95.22358  1.000 47.59717  ? 80  ASP F OD1 1 
ATOM   6855 O  OD2 . ASP F 1 100 ? -11.08178 4.57085   96.00433  1.000 48.38517  ? 80  ASP F OD2 1 
ATOM   6856 N  N   . PRO F 1 101 ? -10.98520 6.86827   92.13574  1.000 54.31426  ? 81  PRO F N   1 
ATOM   6857 C  CA  . PRO F 1 101 ? -9.82666  6.58656   91.27963  1.000 53.76790  ? 81  PRO F CA  1 
ATOM   6858 C  C   . PRO F 1 101 ? -8.72836  5.88741   92.05983  1.000 59.15624  ? 81  PRO F C   1 
ATOM   6859 O  O   . PRO F 1 101 ? -8.24856  6.40823   93.07849  1.000 58.28174  ? 81  PRO F O   1 
ATOM   6860 C  CB  . PRO F 1 101 ? -9.37583  7.98266   90.81698  1.000 54.84751  ? 81  PRO F CB  1 
ATOM   6861 C  CG  . PRO F 1 101 ? -10.54408 8.89148   91.09488  1.000 53.10782  ? 81  PRO F CG  1 
ATOM   6862 C  CD  . PRO F 1 101 ? -11.21672 8.31278   92.29739  1.000 52.16647  ? 81  PRO F CD  1 
ATOM   6863 N  N   . PRO F 1 102 ? -8.30460  4.70182   91.61898  1.000 57.60063  ? 82  PRO F N   1 
ATOM   6864 C  CA  . PRO F 1 102 ? -7.17713  4.01717   92.25939  1.000 55.73938  ? 82  PRO F CA  1 
ATOM   6865 C  C   . PRO F 1 102 ? -5.80788  4.45618   91.76435  1.000 54.49729  ? 82  PRO F C   1 
ATOM   6866 O  O   . PRO F 1 102 ? -4.81319  3.81209   92.10779  1.000 43.56081  ? 82  PRO F O   1 
ATOM   6867 C  CB  . PRO F 1 102 ? -7.43670  2.54897   91.89378  1.000 46.36603  ? 82  PRO F CB  1 
ATOM   6868 C  CG  . PRO F 1 102 ? -8.06854  2.62902   90.54826  1.000 51.43513  ? 82  PRO F CG  1 
ATOM   6869 C  CD  . PRO F 1 102 ? -8.90617  3.88812   90.54786  1.000 49.85826  ? 82  PRO F CD  1 
ATOM   6870 N  N   . PHE F 1 103 ? -5.73003  5.51894   90.96664  1.000 56.45929  ? 83  PHE F N   1 
ATOM   6871 C  CA  . PHE F 1 103 ? -4.46860  6.00870   90.43353  1.000 54.45530  ? 83  PHE F CA  1 
ATOM   6872 C  C   . PHE F 1 103 ? -4.51824  7.52813   90.35126  1.000 52.62916  ? 83  PHE F C   1 
ATOM   6873 O  O   . PHE F 1 103 ? -5.57962  8.14624   90.46917  1.000 55.58428  ? 83  PHE F O   1 
ATOM   6874 C  CB  . PHE F 1 103 ? -4.16255  5.39204   89.06094  1.000 60.42846  ? 83  PHE F CB  1 
ATOM   6875 C  CG  . PHE F 1 103 ? -5.31489  5.44897   88.09603  1.000 59.28063  ? 83  PHE F CG  1 
ATOM   6876 C  CD1 . PHE F 1 103 ? -5.55577  6.59070   87.34819  1.000 59.67175  ? 83  PHE F CD1 1 
ATOM   6877 C  CD2 . PHE F 1 103 ? -6.15175  4.35657   87.93021  1.000 55.24784  ? 83  PHE F CD2 1 
ATOM   6878 C  CE1 . PHE F 1 103 ? -6.61382  6.64484   86.45936  1.000 60.79921  ? 83  PHE F CE1 1 
ATOM   6879 C  CE2 . PHE F 1 103 ? -7.21130  4.40544   87.04175  1.000 55.88324  ? 83  PHE F CE2 1 
ATOM   6880 C  CZ  . PHE F 1 103 ? -7.44172  5.55021   86.30626  1.000 56.97947  ? 83  PHE F CZ  1 
ATOM   6881 N  N   . ALA F 1 104 ? -3.34777  8.12876   90.14438  1.000 59.39926  ? 84  ALA F N   1 
ATOM   6882 C  CA  . ALA F 1 104 ? -3.19864  9.58270   90.09202  1.000 68.71061  ? 84  ALA F CA  1 
ATOM   6883 C  C   . ALA F 1 104 ? -3.12874  10.01856  88.63177  1.000 72.40631  ? 84  ALA F C   1 
ATOM   6884 O  O   . ALA F 1 104 ? -2.09105  9.87810   87.97957  1.000 73.23289  ? 84  ALA F O   1 
ATOM   6885 C  CB  . ALA F 1 104 ? -1.96055  10.02834  90.86221  1.000 62.20510  ? 84  ALA F CB  1 
ATOM   6886 N  N   . ALA F 1 105 ? -4.23643  10.54967  88.12018  1.000 73.93923  ? 85  ALA F N   1 
ATOM   6887 C  CA  . ALA F 1 105 ? -4.32349  11.02311  86.74733  1.000 80.07801  ? 85  ALA F CA  1 
ATOM   6888 C  C   . ALA F 1 105 ? -4.49079  12.53741  86.71743  1.000 79.90788  ? 85  ALA F C   1 
ATOM   6889 O  O   . ALA F 1 105 ? -5.11251  13.12754  87.60511  1.000 76.17493  ? 85  ALA F O   1 
ATOM   6890 C  CB  . ALA F 1 105 ? -5.48944  10.35821  86.00924  1.000 78.13832  ? 85  ALA F CB  1 
ATOM   6891 N  N   . ASP F 1 106 ? -3.92667  13.16287  85.68639  1.000 85.30742  ? 86  ASP F N   1 
ATOM   6892 C  CA  . ASP F 1 106 ? -4.05619  14.60064  85.51269  1.000 80.57271  ? 86  ASP F CA  1 
ATOM   6893 C  C   . ASP F 1 106 ? -5.43374  14.94976  84.95293  1.000 78.07064  ? 86  ASP F C   1 
ATOM   6894 O  O   . ASP F 1 106 ? -6.21687  14.08122  84.55740  1.000 86.53586  ? 86  ASP F O   1 
ATOM   6895 C  CB  . ASP F 1 106 ? -2.95941  15.13685  84.59326  1.000 83.26991  ? 86  ASP F CB  1 
ATOM   6896 C  CG  . ASP F 1 106 ? -1.64113  15.34544  85.31472  1.000 80.30101  ? 86  ASP F CG  1 
ATOM   6897 O  OD1 . ASP F 1 106 ? -1.57899  15.09463  86.53726  1.000 77.71353  ? 86  ASP F OD1 1 
ATOM   6898 O  OD2 . ASP F 1 106 ? -0.66717  15.76600  84.65564  1.000 76.16749  ? 86  ASP F OD2 1 
ATOM   6899 N  N   . GLU F 1 107 ? -5.72606  16.24748  84.92399  1.000 76.34238  ? 87  GLU F N   1 
ATOM   6900 C  CA  . GLU F 1 107 ? -7.00926  16.70797  84.41511  1.000 87.58378  ? 87  GLU F CA  1 
ATOM   6901 C  C   . GLU F 1 107 ? -7.06860  16.54671  82.90335  1.000 86.92906  ? 87  GLU F C   1 
ATOM   6902 O  O   . GLU F 1 107 ? -6.07022  16.72003  82.20101  1.000 89.19421  ? 87  GLU F O   1 
ATOM   6903 C  CB  . GLU F 1 107 ? -7.25087  18.16927  84.79920  1.000 89.66430  ? 87  GLU F CB  1 
ATOM   6904 C  CG  . GLU F 1 107 ? -6.23267  19.13631  84.22613  1.000 94.16074  ? 87  GLU F CG  1 
ATOM   6905 C  CD  . GLU F 1 107 ? -5.53061  19.94102  85.29693  1.000 102.23110 ? 87  GLU F CD  1 
ATOM   6906 O  OE1 . GLU F 1 107 ? -5.74156  21.17104  85.34834  1.000 97.85578  ? 87  GLU F OE1 1 
ATOM   6907 O  OE2 . GLU F 1 107 ? -4.78091  19.33941  86.09475  1.000 93.80473  ? 87  GLU F OE2 1 
ATOM   6908 N  N   . GLY F 1 108 ? -8.25251  16.21581  82.39925  1.000 84.12726  ? 88  GLY F N   1 
ATOM   6909 C  CA  . GLY F 1 108 ? -8.39887  16.00640  80.97190  1.000 82.53099  ? 88  GLY F CA  1 
ATOM   6910 C  C   . GLY F 1 108 ? -7.87710  14.68022  80.46803  1.000 84.38971  ? 88  GLY F C   1 
ATOM   6911 O  O   . GLY F 1 108 ? -7.91142  14.43854  79.25693  1.000 84.93152  ? 88  GLY F O   1 
ATOM   6912 N  N   . ALA F 1 109 ? -7.39516  13.80810  81.36005  1.000 85.13277  ? 89  ALA F N   1 
ATOM   6913 C  CA  . ALA F 1 109 ? -6.90598  12.50053  80.93831  1.000 80.67820  ? 89  ALA F CA  1 
ATOM   6914 C  C   . ALA F 1 109 ? -8.03112  11.57981  80.48322  1.000 74.99657  ? 89  ALA F C   1 
ATOM   6915 O  O   . ALA F 1 109 ? -7.75893  10.55892  79.84175  1.000 78.55498  ? 89  ALA F O   1 
ATOM   6916 C  CB  . ALA F 1 109 ? -6.11761  11.84234  82.06953  1.000 66.95637  ? 89  ALA F CB  1 
ATOM   6917 N  N   . PHE F 1 110 ? -9.27870  11.91387  80.79920  1.000 71.73377  ? 90  PHE F N   1 
ATOM   6918 C  CA  . PHE F 1 110 ? -10.44378 11.14792  80.39146  1.000 70.20886  ? 90  PHE F CA  1 
ATOM   6919 C  C   . PHE F 1 110 ? -11.50784 12.08317  79.83800  1.000 68.66362  ? 90  PHE F C   1 
ATOM   6920 O  O   . PHE F 1 110 ? -11.58554 13.24890  80.23971  1.000 68.73138  ? 90  PHE F O   1 
ATOM   6921 C  CB  . PHE F 1 110 ? -11.03054 10.35199  81.56827  1.000 64.70705  ? 90  PHE F CB  1 
ATOM   6922 C  CG  . PHE F 1 110 ? -10.06670 9.38213   82.19060  1.000 65.00684  ? 90  PHE F CG  1 
ATOM   6923 C  CD1 . PHE F 1 110 ? -9.75620  8.19040   81.55785  1.000 54.65009  ? 90  PHE F CD1 1 
ATOM   6924 C  CD2 . PHE F 1 110 ? -9.48088  9.65678   83.41568  1.000 62.42153  ? 90  PHE F CD2 1 
ATOM   6925 C  CE1 . PHE F 1 110 ? -8.87203  7.29558   82.12934  1.000 59.43038  ? 90  PHE F CE1 1 
ATOM   6926 C  CE2 . PHE F 1 110 ? -8.59627  8.76496   83.99354  1.000 55.57215  ? 90  PHE F CE2 1 
ATOM   6927 C  CZ  . PHE F 1 110 ? -8.29153  7.58278   83.34958  1.000 58.45704  ? 90  PHE F CZ  1 
ATOM   6928 N  N   . PRO F 1 111 ? -12.33326 11.60530  78.91079  1.000 66.88910  ? 91  PRO F N   1 
ATOM   6929 C  CA  . PRO F 1 111 ? -13.47946 12.39921  78.45583  1.000 65.15209  ? 91  PRO F CA  1 
ATOM   6930 C  C   . PRO F 1 111 ? -14.47714 12.59109  79.58334  1.000 64.79280  ? 91  PRO F C   1 
ATOM   6931 O  O   . PRO F 1 111 ? -14.48138 11.81817  80.55343  1.000 63.46388  ? 91  PRO F O   1 
ATOM   6932 C  CB  . PRO F 1 111 ? -14.06890 11.55072  77.31762  1.000 66.72974  ? 91  PRO F CB  1 
ATOM   6933 C  CG  . PRO F 1 111 ? -13.58604 10.17064  77.58192  1.000 57.22802  ? 91  PRO F CG  1 
ATOM   6934 C  CD  . PRO F 1 111 ? -12.22919 10.32200  78.19588  1.000 59.96217  ? 91  PRO F CD  1 
ATOM   6935 N  N   . PRO F 1 112 ? -15.33476 13.60861  79.49952  1.000 72.40847  ? 92  PRO F N   1 
ATOM   6936 C  CA  . PRO F 1 112 ? -16.25168 13.88926  80.61260  1.000 74.95398  ? 92  PRO F CA  1 
ATOM   6937 C  C   . PRO F 1 112 ? -17.22413 12.74198  80.84928  1.000 64.14806  ? 92  PRO F C   1 
ATOM   6938 O  O   . PRO F 1 112 ? -17.69791 12.09736  79.91120  1.000 73.89470  ? 92  PRO F O   1 
ATOM   6939 C  CB  . PRO F 1 112 ? -16.97896 15.16173  80.16093  1.000 67.09551  ? 92  PRO F CB  1 
ATOM   6940 C  CG  . PRO F 1 112 ? -16.85773 15.15995  78.67171  1.000 72.44963  ? 92  PRO F CG  1 
ATOM   6941 C  CD  . PRO F 1 112 ? -15.51959 14.54824  78.38007  1.000 69.43216  ? 92  PRO F CD  1 
ATOM   6942 N  N   . ALA F 1 113 ? -17.51496 12.49051  82.12431  1.000 57.05982  ? 93  ALA F N   1 
ATOM   6943 C  CA  . ALA F 1 113 ? -18.42860 11.42689  82.51220  1.000 59.50183  ? 93  ALA F CA  1 
ATOM   6944 C  C   . ALA F 1 113 ? -19.16965 11.84263  83.77424  1.000 60.43670  ? 93  ALA F C   1 
ATOM   6945 O  O   . ALA F 1 113 ? -18.61796 12.53263  84.63519  1.000 63.34831  ? 93  ALA F O   1 
ATOM   6946 C  CB  . ALA F 1 113 ? -17.68951 10.10296  82.74028  1.000 50.32970  ? 93  ALA F CB  1 
ATOM   6947 N  N   . GLU F 1 114 ? -20.42528 11.40749  83.88012  1.000 55.10027  ? 94  GLU F N   1 
ATOM   6948 C  CA  . GLU F 1 114 ? -21.26595 11.77016  85.01515  1.000 60.50377  ? 94  GLU F CA  1 
ATOM   6949 C  C   . GLU F 1 114 ? -21.06291 10.83828  86.20564  1.000 64.13070  ? 94  GLU F C   1 
ATOM   6950 O  O   . GLU F 1 114 ? -20.92325 11.30342  87.34102  1.000 68.49486  ? 94  GLU F O   1 
ATOM   6951 C  CB  . GLU F 1 114 ? -22.73777 11.78381  84.59370  1.000 57.41877  ? 94  GLU F CB  1 
ATOM   6952 C  CG  . GLU F 1 114 ? -23.08582 12.90633  83.63202  1.000 72.38893  ? 94  GLU F CG  1 
ATOM   6953 C  CD  . GLU F 1 114 ? -23.03909 14.27090  84.29423  1.000 72.11219  ? 94  GLU F CD  1 
ATOM   6954 O  OE1 . GLU F 1 114 ? -23.65100 14.43101  85.37216  1.000 72.60497  ? 94  GLU F OE1 1 
ATOM   6955 O  OE2 . GLU F 1 114 ? -22.38591 15.18219  83.74330  1.000 75.02646  ? 94  GLU F OE2 1 
ATOM   6956 N  N   . ARG F 1 115 ? -21.05026 9.52734   85.96835  1.000 63.39307  ? 95  ARG F N   1 
ATOM   6957 C  CA  . ARG F 1 115 ? -20.82355 8.52921   87.01482  1.000 59.04574  ? 95  ARG F CA  1 
ATOM   6958 C  C   . ARG F 1 115 ? -19.80458 7.51680   86.51130  1.000 62.67478  ? 95  ARG F C   1 
ATOM   6959 O  O   . ARG F 1 115 ? -20.15840 6.38396   86.15518  1.000 61.88445  ? 95  ARG F O   1 
ATOM   6960 C  CB  . ARG F 1 115 ? -22.12552 7.83526   87.41915  1.000 61.27624  ? 95  ARG F CB  1 
ATOM   6961 C  CG  . ARG F 1 115 ? -23.09840 8.71823   88.17938  1.000 67.85117  ? 95  ARG F CG  1 
ATOM   6962 C  CD  . ARG F 1 115 ? -24.46028 8.05260   88.27344  1.000 60.12967  ? 95  ARG F CD  1 
ATOM   6963 N  NE  . ARG F 1 115 ? -24.90605 7.56784   86.97209  1.000 75.64219  ? 95  ARG F NE  1 
ATOM   6964 C  CZ  . ARG F 1 115 ? -25.42579 8.33545   86.02349  1.000 79.66486  ? 95  ARG F CZ  1 
ATOM   6965 N  NH1 . ARG F 1 115 ? -25.58336 9.63766   86.19670  1.000 71.78758  ? 95  ARG F NH1 1 
ATOM   6966 N  NH2 . ARG F 1 115 ? -25.79261 7.78347   84.87006  1.000 76.99166  ? 95  ARG F NH2 1 
ATOM   6967 N  N   . PRO F 1 116 ? -18.52660 7.88653   86.47237  1.000 60.23304  ? 96  PRO F N   1 
ATOM   6968 C  CA  . PRO F 1 116 ? -17.50738 6.94537   85.99919  1.000 50.41205  ? 96  PRO F CA  1 
ATOM   6969 C  C   . PRO F 1 116 ? -17.12412 5.94341   87.07656  1.000 52.87560  ? 96  PRO F C   1 
ATOM   6970 O  O   . PRO F 1 116 ? -17.05694 6.26880   88.26465  1.000 58.50954  ? 96  PRO F O   1 
ATOM   6971 C  CB  . PRO F 1 116 ? -16.32722 7.85808   85.64935  1.000 52.15085  ? 96  PRO F CB  1 
ATOM   6972 C  CG  . PRO F 1 116 ? -16.46643 8.99653   86.60522  1.000 49.68563  ? 96  PRO F CG  1 
ATOM   6973 C  CD  . PRO F 1 116 ? -17.95096 9.20116   86.80903  1.000 52.58347  ? 96  PRO F CD  1 
ATOM   6974 N  N   . LEU F 1 117 ? -16.88435 4.70780   86.65001  1.000 47.23403  ? 97  LEU F N   1 
ATOM   6975 C  CA  . LEU F 1 117 ? -16.28830 3.68968   87.49983  1.000 43.90508  ? 97  LEU F CA  1 
ATOM   6976 C  C   . LEU F 1 117 ? -14.86770 3.40502   87.03244  1.000 40.35599  ? 97  LEU F C   1 
ATOM   6977 O  O   . LEU F 1 117 ? -14.48246 3.72890   85.90577  1.000 45.53074  ? 97  LEU F O   1 
ATOM   6978 C  CB  . LEU F 1 117 ? -17.11403 2.39877   87.49965  1.000 45.35623  ? 97  LEU F CB  1 
ATOM   6979 C  CG  . LEU F 1 117 ? -18.40606 2.43634   88.31754  1.000 46.70158  ? 97  LEU F CG  1 
ATOM   6980 C  CD1 . LEU F 1 117 ? -19.56877 2.89449   87.46239  1.000 42.93333  ? 97  LEU F CD1 1 
ATOM   6981 C  CD2 . LEU F 1 117 ? -18.69466 1.08351   88.94480  1.000 46.51796  ? 97  LEU F CD2 1 
ATOM   6982 N  N   . TYR F 1 118 ? -14.08698 2.79164   87.91563  1.000 39.05288  ? 98  TYR F N   1 
ATOM   6983 C  CA  . TYR F 1 118 ? -12.67053 2.56062   87.68267  1.000 42.75621  ? 98  TYR F CA  1 
ATOM   6984 C  C   . TYR F 1 118 ? -12.36107 1.07760   87.80705  1.000 42.32664  ? 98  TYR F C   1 
ATOM   6985 O  O   . TYR F 1 118 ? -12.74591 0.43431   88.79250  1.000 44.00643  ? 98  TYR F O   1 
ATOM   6986 C  CB  . TYR F 1 118 ? -11.81777 3.37268   88.65915  1.000 44.91633  ? 98  TYR F CB  1 
ATOM   6987 C  CG  . TYR F 1 118 ? -11.87951 4.86190   88.41151  1.000 51.51332  ? 98  TYR F CG  1 
ATOM   6988 C  CD1 . TYR F 1 118 ? -12.86868 5.64385   88.99497  1.000 49.69471  ? 98  TYR F CD1 1 
ATOM   6989 C  CD2 . TYR F 1 118 ? -10.95446 5.48545   87.58359  1.000 50.48219  ? 98  TYR F CD2 1 
ATOM   6990 C  CE1 . TYR F 1 118 ? -12.93263 7.00556   88.76580  1.000 52.21069  ? 98  TYR F CE1 1 
ATOM   6991 C  CE2 . TYR F 1 118 ? -11.00938 6.84831   87.34857  1.000 57.67621  ? 98  TYR F CE2 1 
ATOM   6992 C  CZ  . TYR F 1 118 ? -12.00012 7.60266   87.94233  1.000 54.14076  ? 98  TYR F CZ  1 
ATOM   6993 O  OH  . TYR F 1 118 ? -12.05787 8.95727   87.71034  1.000 40.37256  ? 98  TYR F OH  1 
ATOM   6994 N  N   . LEU F 1 119 ? -11.67012 0.54975   86.80066  1.000 43.58134  ? 99  LEU F N   1 
ATOM   6995 C  CA  . LEU F 1 119 ? -11.22694 -0.83545  86.76294  1.000 44.50284  ? 99  LEU F CA  1 
ATOM   6996 C  C   . LEU F 1 119 ? -9.75148  -0.89638  87.13153  1.000 47.97590  ? 99  LEU F C   1 
ATOM   6997 O  O   . LEU F 1 119 ? -8.93642  -0.15663  86.57000  1.000 48.25851  ? 99  LEU F O   1 
ATOM   6998 C  CB  . LEU F 1 119 ? -11.44959 -1.43373  85.37332  1.000 46.40724  ? 99  LEU F CB  1 
ATOM   6999 C  CG  . LEU F 1 119 ? -10.74852 -2.75771  85.06894  1.000 45.79520  ? 99  LEU F CG  1 
ATOM   7000 C  CD1 . LEU F 1 119 ? -11.44694 -3.91496  85.76115  1.000 43.80580  ? 99  LEU F CD1 1 
ATOM   7001 C  CD2 . LEU F 1 119 ? -10.67710 -2.98196  83.57149  1.000 43.99469  ? 99  LEU F CD2 1 
ATOM   7002 N  N   . SER F 1 120 ? -9.41237  -1.77213  88.07337  1.000 46.61057  ? 100 SER F N   1 
ATOM   7003 C  CA  . SER F 1 120 ? -8.03376  -1.91471  88.51118  1.000 43.09230  ? 100 SER F CA  1 
ATOM   7004 C  C   . SER F 1 120 ? -7.77458  -3.36924  88.87244  1.000 48.47422  ? 100 SER F C   1 
ATOM   7005 O  O   . SER F 1 120 ? -8.69457  -4.18970  88.95232  1.000 46.92725  ? 100 SER F O   1 
ATOM   7006 C  CB  . SER F 1 120 ? -7.72379  -0.99145  89.69831  1.000 56.35305  ? 100 SER F CB  1 
ATOM   7007 O  OG  . SER F 1 120 ? -8.55086  -1.28363  90.81255  1.000 44.21598  ? 100 SER F OG  1 
ATOM   7008 N  N   . ARG F 1 121 ? -6.49180  -3.68024  89.06305  1.000 51.04382  ? 101 ARG F N   1 
ATOM   7009 C  CA  . ARG F 1 121 ? -6.05638  -4.97365  89.58853  1.000 52.57182  ? 101 ARG F CA  1 
ATOM   7010 C  C   . ARG F 1 121 ? -6.64462  -6.13707  88.79282  1.000 54.76995  ? 101 ARG F C   1 
ATOM   7011 O  O   . ARG F 1 121 ? -7.11675  -7.12824  89.35463  1.000 56.52884  ? 101 ARG F O   1 
ATOM   7012 C  CB  . ARG F 1 121 ? -6.40509  -5.09326  91.07130  1.000 56.55736  ? 101 ARG F CB  1 
ATOM   7013 C  CG  . ARG F 1 121 ? -5.70688  -4.06875  91.94586  1.000 56.69031  ? 101 ARG F CG  1 
ATOM   7014 C  CD  . ARG F 1 121 ? -5.95328  -4.35051  93.41294  1.000 58.37766  ? 101 ARG F CD  1 
ATOM   7015 N  NE  . ARG F 1 121 ? -4.84457  -3.90943  94.24926  1.000 62.76413  ? 101 ARG F NE  1 
ATOM   7016 C  CZ  . ARG F 1 121 ? -4.64537  -4.31757  95.49445  1.000 65.60763  ? 101 ARG F CZ  1 
ATOM   7017 N  NH1 . ARG F 1 121 ? -5.45610  -5.18728  96.07202  1.000 65.63533  ? 101 ARG F NH1 1 
ATOM   7018 N  NH2 . ARG F 1 121 ? -3.60325  -3.84674  96.17434  1.000 74.51589  ? 101 ARG F NH2 1 
ATOM   7019 N  N   . LEU F 1 122 ? -6.63285  -6.00543  87.46912  1.000 55.03212  ? 102 LEU F N   1 
ATOM   7020 C  CA  . LEU F 1 122 ? -7.04414  -7.10245  86.60553  1.000 47.11514  ? 102 LEU F CA  1 
ATOM   7021 C  C   . LEU F 1 122 ? -6.00854  -8.21621  86.67865  1.000 49.84935  ? 102 LEU F C   1 
ATOM   7022 O  O   . LEU F 1 122 ? -4.81626  -7.97903  86.47064  1.000 48.65700  ? 102 LEU F O   1 
ATOM   7023 C  CB  . LEU F 1 122 ? -7.20212  -6.61150  85.16821  1.000 53.45586  ? 102 LEU F CB  1 
ATOM   7024 C  CG  . LEU F 1 122 ? -7.72243  -7.59971  84.12197  1.000 54.39253  ? 102 LEU F CG  1 
ATOM   7025 C  CD1 . LEU F 1 122 ? -9.20301  -7.88328  84.32844  1.000 50.19281  ? 102 LEU F CD1 1 
ATOM   7026 C  CD2 . LEU F 1 122 ? -7.46432  -7.05742  82.72899  1.000 49.61524  ? 102 LEU F CD2 1 
ATOM   7027 N  N   . ALA F 1 123 ? -6.45658  -9.43260  86.98175  1.000 46.09482  ? 103 ALA F N   1 
ATOM   7028 C  CA  . ALA F 1 123 ? -5.53551  -10.54267 87.19215  1.000 54.42371  ? 103 ALA F CA  1 
ATOM   7029 C  C   . ALA F 1 123 ? -6.15266  -11.83321 86.67034  1.000 62.22406  ? 103 ALA F C   1 
ATOM   7030 O  O   . ALA F 1 123 ? -7.36197  -12.04353 86.79029  1.000 60.66995  ? 103 ALA F O   1 
ATOM   7031 C  CB  . ALA F 1 123 ? -5.17054  -10.68658 88.67631  1.000 60.96917  ? 103 ALA F CB  1 
ATOM   7032 N  N   . VAL F 1 124 ? -5.31011  -12.69575 86.10466  1.000 62.37742  ? 104 VAL F N   1 
ATOM   7033 C  CA  . VAL F 1 124 ? -5.74277  -13.91755 85.43784  1.000 69.80545  ? 104 VAL F CA  1 
ATOM   7034 C  C   . VAL F 1 124 ? -4.75477  -15.01692 85.79947  1.000 69.73109  ? 104 VAL F C   1 
ATOM   7035 O  O   . VAL F 1 124 ? -3.57453  -14.93358 85.42556  1.000 70.54519  ? 104 VAL F O   1 
ATOM   7036 C  CB  . VAL F 1 124 ? -5.81419  -13.73901 83.91336  1.000 63.84726  ? 104 VAL F CB  1 
ATOM   7037 C  CG1 . VAL F 1 124 ? -7.14666  -13.13910 83.51894  1.000 61.97648  ? 104 VAL F CG1 1 
ATOM   7038 C  CG2 . VAL F 1 124 ? -4.68532  -12.83997 83.43660  1.000 54.10494  ? 104 VAL F CG2 1 
ATOM   7039 N  N   . ALA F 1 125 ? -5.24738  -16.04876 86.51259  1.000 64.11220  ? 105 ALA F N   1 
ATOM   7040 C  CA  . ALA F 1 125 ? -4.40725  -17.08705 87.10000  1.000 70.55749  ? 105 ALA F CA  1 
ATOM   7041 C  C   . ALA F 1 125 ? -3.35954  -17.55913 86.09404  1.000 80.09757  ? 105 ALA F C   1 
ATOM   7042 O  O   . ALA F 1 125 ? -3.67732  -17.75552 84.91203  1.000 83.20811  ? 105 ALA F O   1 
ATOM   7043 C  CB  . ALA F 1 125 ? -5.25857  -18.27337 87.55569  1.000 71.66957  ? 105 ALA F CB  1 
ATOM   7044 N  N   . PRO F 1 126 ? -2.10209  -17.71996 86.51529  1.000 82.35978  ? 106 PRO F N   1 
ATOM   7045 C  CA  . PRO F 1 126 ? -1.03395  -18.02777 85.54839  1.000 81.73973  ? 106 PRO F CA  1 
ATOM   7046 C  C   . PRO F 1 126 ? -1.27133  -19.29488 84.74403  1.000 83.18976  ? 106 PRO F C   1 
ATOM   7047 O  O   . PRO F 1 126 ? -0.87573  -19.35552 83.57330  1.000 76.27786  ? 106 PRO F O   1 
ATOM   7048 C  CB  . PRO F 1 126 ? 0.21207   -18.14849 86.44101  1.000 81.07935  ? 106 PRO F CB  1 
ATOM   7049 C  CG  . PRO F 1 126 ? -0.09811  -17.31169 87.63935  1.000 76.20972  ? 106 PRO F CG  1 
ATOM   7050 C  CD  . PRO F 1 126 ? -1.57301  -17.50101 87.86922  1.000 73.19034  ? 106 PRO F CD  1 
ATOM   7051 N  N   . GLU F 1 127 ? -1.89610  -20.31644 85.33939  1.000 81.65527  ? 107 GLU F N   1 
ATOM   7052 C  CA  . GLU F 1 127 ? -2.22283  -21.52972 84.59578  1.000 86.78603  ? 107 GLU F CA  1 
ATOM   7053 C  C   . GLU F 1 127 ? -3.17239  -21.25085 83.43794  1.000 91.49707  ? 107 GLU F C   1 
ATOM   7054 O  O   . GLU F 1 127 ? -3.22014  -22.03229 82.48057  1.000 87.62112  ? 107 GLU F O   1 
ATOM   7055 C  CB  . GLU F 1 127 ? -2.83417  -22.57170 85.53755  1.000 94.88008  ? 107 GLU F CB  1 
ATOM   7056 C  CG  . GLU F 1 127 ? -3.01974  -23.94909 84.91667  1.000 110.79096 ? 107 GLU F CG  1 
ATOM   7057 C  CD  . GLU F 1 127 ? -3.62139  -24.95107 85.88231  1.000 117.09688 ? 107 GLU F CD  1 
ATOM   7058 O  OE1 . GLU F 1 127 ? -3.88199  -24.57593 87.04484  1.000 120.94868 ? 107 GLU F OE1 1 
ATOM   7059 O  OE2 . GLU F 1 127 ? -3.83303  -26.11387 85.47720  1.000 111.29376 ? 107 GLU F OE2 1 
ATOM   7060 N  N   . TRP F 1 128 ? -3.91753  -20.15143 83.50001  1.000 90.65831  ? 108 TRP F N   1 
ATOM   7061 C  CA  . TRP F 1 128 ? -4.87285  -19.78915 82.46507  1.000 83.53518  ? 108 TRP F CA  1 
ATOM   7062 C  C   . TRP F 1 128 ? -4.29144  -18.86600 81.40171  1.000 84.00593  ? 108 TRP F C   1 
ATOM   7063 O  O   . TRP F 1 128 ? -5.02954  -18.43937 80.50849  1.000 91.73988  ? 108 TRP F O   1 
ATOM   7064 C  CB  . TRP F 1 128 ? -6.10362  -19.13784 83.09853  1.000 73.32631  ? 108 TRP F CB  1 
ATOM   7065 C  CG  . TRP F 1 128 ? -6.89419  -20.08354 83.93743  1.000 73.14724  ? 108 TRP F CG  1 
ATOM   7066 C  CD1 . TRP F 1 128 ? -6.90251  -20.16413 85.29803  1.000 75.38800  ? 108 TRP F CD1 1 
ATOM   7067 C  CD2 . TRP F 1 128 ? -7.78498  -21.10023 83.46956  1.000 79.82042  ? 108 TRP F CD2 1 
ATOM   7068 N  NE1 . TRP F 1 128 ? -7.75021  -21.16325 85.70898  1.000 85.16363  ? 108 TRP F NE1 1 
ATOM   7069 C  CE2 . TRP F 1 128 ? -8.30428  -21.75449 84.60419  1.000 79.82665  ? 108 TRP F CE2 1 
ATOM   7070 C  CE3 . TRP F 1 128 ? -8.19713  -21.51926 82.20069  1.000 71.80663  ? 108 TRP F CE3 1 
ATOM   7071 C  CZ2 . TRP F 1 128 ? -9.21430  -22.80469 84.50815  1.000 76.97441  ? 108 TRP F CZ2 1 
ATOM   7072 C  CZ3 . TRP F 1 128 ? -9.09984  -22.56120 82.10759  1.000 70.23078  ? 108 TRP F CZ3 1 
ATOM   7073 C  CH2 . TRP F 1 128 ? -9.59827  -23.19206 83.25375  1.000 76.80379  ? 108 TRP F CH2 1 
ATOM   7074 N  N   . LEU F 1 129 ? -3.00108  -18.54138 81.46612  1.000 80.34032  ? 109 LEU F N   1 
ATOM   7075 C  CA  . LEU F 1 129 ? -2.37268  -17.73848 80.41535  1.000 85.71444  ? 109 LEU F CA  1 
ATOM   7076 C  C   . LEU F 1 129 ? -1.79247  -18.64668 79.32934  1.000 88.70467  ? 109 LEU F C   1 
ATOM   7077 O  O   . LEU F 1 129 ? -0.59362  -18.66788 79.04599  1.000 79.48747  ? 109 LEU F O   1 
ATOM   7078 C  CB  . LEU F 1 129 ? -1.31563  -16.81226 81.00501  1.000 89.59469  ? 109 LEU F CB  1 
ATOM   7079 C  CG  . LEU F 1 129 ? -1.88713  -15.63119 81.79587  1.000 88.51824  ? 109 LEU F CG  1 
ATOM   7080 C  CD1 . LEU F 1 129 ? -0.89180  -14.47594 81.85161  1.000 80.20425  ? 109 LEU F CD1 1 
ATOM   7081 C  CD2 . LEU F 1 129 ? -3.22216  -15.17738 81.20627  1.000 80.17551  ? 109 LEU F CD2 1 
ATOM   7082 N  N   . THR F 1 130 ? -2.69390  -19.40430 78.71476  1.000 93.50925  ? 110 THR F N   1 
ATOM   7083 C  CA  . THR F 1 130 ? -2.34262  -20.35186 77.66698  1.000 96.63364  ? 110 THR F CA  1 
ATOM   7084 C  C   . THR F 1 130 ? -2.83717  -19.87008 76.30647  1.000 94.14065  ? 110 THR F C   1 
ATOM   7085 O  O   . THR F 1 130 ? -3.62096  -18.92458 76.21786  1.000 83.03072  ? 110 THR F O   1 
ATOM   7086 C  CB  . THR F 1 130 ? -2.92996  -21.74510 77.96518  1.000 99.13107  ? 110 THR F CB  1 
ATOM   7087 O  OG1 . THR F 1 130 ? -2.10559  -22.41705 78.92559  1.000 97.72984  ? 110 THR F OG1 1 
ATOM   7088 C  CG2 . THR F 1 130 ? -3.02353  -22.57867 76.69678  1.000 94.15913  ? 110 THR F CG2 1 
ATOM   7089 N  N   . SER F 1 133 ? -5.33425  -17.33197 76.61332  1.000 82.74137  ? 113 SER F N   1 
ATOM   7090 C  CA  . SER F 1 133 ? -6.70456  -17.82822 76.63082  1.000 75.54025  ? 113 SER F CA  1 
ATOM   7091 C  C   . SER F 1 133 ? -7.69784  -16.67292 76.61571  1.000 72.83621  ? 113 SER F C   1 
ATOM   7092 O  O   . SER F 1 133 ? -7.38504  -15.58020 76.13842  1.000 66.97843  ? 113 SER F O   1 
ATOM   7093 C  CB  . SER F 1 133 ? -6.94205  -18.71415 77.85510  1.000 85.21891  ? 113 SER F CB  1 
ATOM   7094 O  OG  . SER F 1 133 ? -6.66520  -18.01291 79.05450  1.000 80.25250  ? 113 SER F OG  1 
ATOM   7095 N  N   . LEU F 1 134 ? -8.89712  -16.91915 77.14769  1.000 66.33643  ? 114 LEU F N   1 
ATOM   7096 C  CA  . LEU F 1 134 ? -9.97365  -15.93550 77.13623  1.000 59.42042  ? 114 LEU F CA  1 
ATOM   7097 C  C   . LEU F 1 134 ? -10.47623 -15.61103 78.53906  1.000 59.02590  ? 114 LEU F C   1 
ATOM   7098 O  O   . LEU F 1 134 ? -11.57979 -15.07664 78.69109  1.000 43.39378  ? 114 LEU F O   1 
ATOM   7099 C  CB  . LEU F 1 134 ? -11.12937 -16.42283 76.26081  1.000 58.70313  ? 114 LEU F CB  1 
ATOM   7100 C  CG  . LEU F 1 134 ? -10.78778 -16.75650 74.80773  1.000 56.11075  ? 114 LEU F CG  1 
ATOM   7101 C  CD1 . LEU F 1 134 ? -12.05007 -17.10166 74.02631  1.000 56.69894  ? 114 LEU F CD1 1 
ATOM   7102 C  CD2 . LEU F 1 134 ? -10.02517 -15.61468 74.13921  1.000 51.62794  ? 114 LEU F CD2 1 
ATOM   7103 N  N   . VAL F 1 135 ? -9.69367  -15.92860 79.57170  1.000 63.04998  ? 115 VAL F N   1 
ATOM   7104 C  CA  . VAL F 1 135 ? -10.11237 -15.61835 80.93592  1.000 61.88500  ? 115 VAL F CA  1 
ATOM   7105 C  C   . VAL F 1 135 ? -10.12370 -14.11050 81.15723  1.000 59.89549  ? 115 VAL F C   1 
ATOM   7106 O  O   . VAL F 1 135 ? -11.01700 -13.56967 81.82544  1.000 46.05730  ? 115 VAL F O   1 
ATOM   7107 C  CB  . VAL F 1 135 ? -9.20191  -16.33754 81.94616  1.000 69.84283  ? 115 VAL F CB  1 
ATOM   7108 C  CG1 . VAL F 1 135 ? -9.86843  -16.40002 83.31882  1.000 70.47225  ? 115 VAL F CG1 1 
ATOM   7109 C  CG2 . VAL F 1 135 ? -8.85648  -17.72754 81.44100  1.000 68.53186  ? 115 VAL F CG2 1 
ATOM   7110 N  N   . GLY F 1 136 ? -9.13225  -13.40899 80.59987  1.000 47.23488  ? 116 GLY F N   1 
ATOM   7111 C  CA  . GLY F 1 136 ? -9.16312  -11.95849 80.61623  1.000 44.76449  ? 116 GLY F CA  1 
ATOM   7112 C  C   . GLY F 1 136 ? -10.37195 -11.39451 79.89713  1.000 53.36787  ? 116 GLY F C   1 
ATOM   7113 O  O   . GLY F 1 136 ? -10.91955 -10.36943 80.30774  1.000 58.52181  ? 116 GLY F O   1 
ATOM   7114 N  N   . LEU F 1 137 ? -10.81236 -12.05672 78.82342  1.000 53.61953  ? 117 LEU F N   1 
ATOM   7115 C  CA  . LEU F 1 137 ? -12.04762 -11.65186 78.15699  1.000 52.89800  ? 117 LEU F CA  1 
ATOM   7116 C  C   . LEU F 1 137 ? -13.24045 -11.77990 79.09556  1.000 48.14127  ? 117 LEU F C   1 
ATOM   7117 O  O   . LEU F 1 137 ? -14.08866 -10.88293 79.16557  1.000 47.36224  ? 117 LEU F O   1 
ATOM   7118 C  CB  . LEU F 1 137 ? -12.27060 -12.49064 76.89703  1.000 49.25529  ? 117 LEU F CB  1 
ATOM   7119 C  CG  . LEU F 1 137 ? -13.59302 -12.27588 76.15623  1.000 47.74644  ? 117 LEU F CG  1 
ATOM   7120 C  CD1 . LEU F 1 137 ? -13.58695 -10.94008 75.42536  1.000 41.25456  ? 117 LEU F CD1 1 
ATOM   7121 C  CD2 . LEU F 1 137 ? -13.88317 -13.42578 75.19310  1.000 55.40620  ? 117 LEU F CD2 1 
ATOM   7122 N  N   . ARG F 1 138 ? -13.32638 -12.90343 79.81427  1.000 47.78934  ? 118 ARG F N   1 
ATOM   7123 C  CA  . ARG F 1 138 ? -14.39130 -13.09123 80.79428  1.000 46.79389  ? 118 ARG F CA  1 
ATOM   7124 C  C   . ARG F 1 138 ? -14.37047 -11.98506 81.83911  1.000 48.42464  ? 118 ARG F C   1 
ATOM   7125 O  O   . ARG F 1 138 ? -15.40963 -11.39610 82.16034  1.000 48.90410  ? 118 ARG F O   1 
ATOM   7126 C  CB  . ARG F 1 138 ? -14.25313 -14.45893 81.46690  1.000 47.68458  ? 118 ARG F CB  1 
ATOM   7127 C  CG  . ARG F 1 138 ? -14.44224 -15.64521 80.53978  1.000 54.82160  ? 118 ARG F CG  1 
ATOM   7128 C  CD  . ARG F 1 138 ? -14.22677 -16.95720 81.28067  1.000 58.78124  ? 118 ARG F CD  1 
ATOM   7129 N  NE  . ARG F 1 138 ? -14.31512 -18.11555 80.39918  1.000 54.49033  ? 118 ARG F NE  1 
ATOM   7130 C  CZ  . ARG F 1 138 ? -15.42422 -18.81031 80.18350  1.000 60.71881  ? 118 ARG F CZ  1 
ATOM   7131 N  NH1 . ARG F 1 138 ? -16.56648 -18.49184 80.77249  1.000 52.68208  ? 118 ARG F NH1 1 
ATOM   7132 N  NH2 . ARG F 1 138 ? -15.38720 -19.85008 79.35539  1.000 58.88493  ? 118 ARG F NH2 1 
ATOM   7133 N  N   . CYS F 1 139 ? -13.18450 -11.68514 82.37420  1.000 50.78207  ? 119 CYS F N   1 
ATOM   7134 C  CA  . CYS F 1 139 ? -13.07348 -10.67601 83.42164  1.000 47.13575  ? 119 CYS F CA  1 
ATOM   7135 C  C   . CYS F 1 139 ? -13.46831 -9.29706  82.91037  1.000 52.32782  ? 119 CYS F C   1 
ATOM   7136 O  O   . CYS F 1 139 ? -14.19669 -8.56501  83.58785  1.000 51.59283  ? 119 CYS F O   1 
ATOM   7137 C  CB  . CYS F 1 139 ? -11.65007 -10.65284 83.97771  1.000 52.93714  ? 119 CYS F CB  1 
ATOM   7138 S  SG  . CYS F 1 139 ? -11.13754 -12.18303 84.78210  1.000 48.94015  ? 119 CYS F SG  1 
ATOM   7139 N  N   . LEU F 1 140 ? -13.00392 -8.92630  81.71354  1.000 51.31921  ? 120 LEU F N   1 
ATOM   7140 C  CA  . LEU F 1 140 ? -13.29212 -7.59534  81.18741  1.000 40.43192  ? 120 LEU F CA  1 
ATOM   7141 C  C   . LEU F 1 140 ? -14.75788 -7.45089  80.79666  1.000 48.42064  ? 120 LEU F C   1 
ATOM   7142 O  O   . LEU F 1 140 ? -15.36426 -6.39485  81.02357  1.000 49.08238  ? 120 LEU F O   1 
ATOM   7143 C  CB  . LEU F 1 140 ? -12.37818 -7.29744  80.00218  1.000 42.51709  ? 120 LEU F CB  1 
ATOM   7144 C  CG  . LEU F 1 140 ? -11.05010 -6.66360  80.41273  1.000 47.83680  ? 120 LEU F CG  1 
ATOM   7145 C  CD1 . LEU F 1 140 ? -10.04394 -6.70222  79.28290  1.000 56.21024  ? 120 LEU F CD1 1 
ATOM   7146 C  CD2 . LEU F 1 140 ? -11.29910 -5.23590  80.85232  1.000 47.09283  ? 120 LEU F CD2 1 
ATOM   7147 N  N   . ARG F 1 141 ? -15.34698 -8.49364  80.20764  1.000 50.25078  ? 121 ARG F N   1 
ATOM   7148 C  CA  . ARG F 1 141 ? -16.78131 -8.47434  79.94806  1.000 48.63447  ? 121 ARG F CA  1 
ATOM   7149 C  C   . ARG F 1 141 ? -17.56226 -8.30523  81.24530  1.000 41.65094  ? 121 ARG F C   1 
ATOM   7150 O  O   . ARG F 1 141 ? -18.46671 -7.46135  81.33641  1.000 45.62585  ? 121 ARG F O   1 
ATOM   7151 C  CB  . ARG F 1 141 ? -17.19117 -9.75899  79.22554  1.000 46.47588  ? 121 ARG F CB  1 
ATOM   7152 C  CG  . ARG F 1 141 ? -18.61089 -9.76482  78.67964  1.000 49.46110  ? 121 ARG F CG  1 
ATOM   7153 C  CD  . ARG F 1 141 ? -18.82110 -10.93948 77.72700  1.000 59.14330  ? 121 ARG F CD  1 
ATOM   7154 N  NE  . ARG F 1 141 ? -20.20191 -11.05055 77.26928  1.000 59.47169  ? 121 ARG F NE  1 
ATOM   7155 C  CZ  . ARG F 1 141 ? -20.68790 -10.44397 76.19462  1.000 56.63032  ? 121 ARG F CZ  1 
ATOM   7156 N  NH1 . ARG F 1 141 ? -19.93366 -9.65790  75.44371  1.000 54.70383  ? 121 ARG F NH1 1 
ATOM   7157 N  NH2 . ARG F 1 141 ? -21.96272 -10.63091 75.86497  1.000 51.71555  ? 121 ARG F NH2 1 
ATOM   7158 N  N   . ARG F 1 142 ? -17.22044 -9.10569  82.26321  1.000 42.03641  ? 122 ARG F N   1 
ATOM   7159 C  CA  . ARG F 1 142 ? -17.88946 -9.00247  83.55366  1.000 47.91532  ? 122 ARG F CA  1 
ATOM   7160 C  C   . ARG F 1 142 ? -17.74576 -7.60413  84.13705  1.000 50.32250  ? 122 ARG F C   1 
ATOM   7161 O  O   . ARG F 1 142 ? -18.70461 -7.05642  84.68679  1.000 43.68805  ? 122 ARG F O   1 
ATOM   7162 C  CB  . ARG F 1 142 ? -17.32619 -10.04637 84.51600  1.000 43.67579  ? 122 ARG F CB  1 
ATOM   7163 C  CG  . ARG F 1 142 ? -18.04258 -10.10987 85.85584  1.000 53.03163  ? 122 ARG F CG  1 
ATOM   7164 C  CD  . ARG F 1 142 ? -19.40370 -10.76698 85.71776  1.000 57.91023  ? 122 ARG F CD  1 
ATOM   7165 N  NE  . ARG F 1 142 ? -20.05328 -10.95242 87.00996  1.000 66.90594  ? 122 ARG F NE  1 
ATOM   7166 C  CZ  . ARG F 1 142 ? -21.14548 -11.67956 87.19854  1.000 62.16191  ? 122 ARG F CZ  1 
ATOM   7167 N  NH1 . ARG F 1 142 ? -21.73477 -12.31277 86.19745  1.000 70.11027  ? 122 ARG F NH1 1 
ATOM   7168 N  NH2 . ARG F 1 142 ? -21.65713 -11.77669 88.42206  1.000 59.81395  ? 122 ARG F NH2 1 
ATOM   7169 N  N   . ALA F 1 143 ? -16.56152 -7.00193  84.00542  1.000 46.66628  ? 123 ALA F N   1 
ATOM   7170 C  CA  . ALA F 1 143 ? -16.33985 -5.66446  84.54543  1.000 48.55678  ? 123 ALA F CA  1 
ATOM   7171 C  C   . ALA F 1 143 ? -17.20126 -4.63021  83.83383  1.000 48.46860  ? 123 ALA F C   1 
ATOM   7172 O  O   . ALA F 1 143 ? -17.83396 -3.78684  84.48120  1.000 50.70006  ? 123 ALA F O   1 
ATOM   7173 C  CB  . ALA F 1 143 ? -14.85982 -5.29468  84.44281  1.000 37.37230  ? 123 ALA F CB  1 
ATOM   7174 N  N   . ILE F 1 144 ? -17.22736 -4.67431  82.49869  1.000 47.58334  ? 124 ILE F N   1 
ATOM   7175 C  CA  . ILE F 1 144 ? -18.02001 -3.71661  81.72952  1.000 49.13202  ? 124 ILE F CA  1 
ATOM   7176 C  C   . ILE F 1 144 ? -19.49542 -3.83159  82.10068  1.000 47.13766  ? 124 ILE F C   1 
ATOM   7177 O  O   . ILE F 1 144 ? -20.17771 -2.82762  82.34456  1.000 52.57346  ? 124 ILE F O   1 
ATOM   7178 C  CB  . ILE F 1 144 ? -17.78960 -3.92927  80.22038  1.000 49.57767  ? 124 ILE F CB  1 
ATOM   7179 C  CG1 . ILE F 1 144 ? -16.35230 -3.55239  79.83998  1.000 46.85793  ? 124 ILE F CG1 1 
ATOM   7180 C  CG2 . ILE F 1 144 ? -18.79808 -3.13586  79.39551  1.000 33.90575  ? 124 ILE F CG2 1 
ATOM   7181 C  CD1 . ILE F 1 144 ? -15.96484 -3.95094  78.43205  1.000 42.38131  ? 124 ILE F CD1 1 
ATOM   7182 N  N   . GLU F 1 145 ? -19.99981 -5.06392  82.18535  1.000 52.58655  ? 125 GLU F N   1 
ATOM   7183 C  CA  . GLU F 1 145 ? -21.42130 -5.26351  82.44996  1.000 51.30006  ? 125 GLU F CA  1 
ATOM   7184 C  C   . GLU F 1 145 ? -21.77780 -4.92519  83.89670  1.000 50.50509  ? 125 GLU F C   1 
ATOM   7185 O  O   . GLU F 1 145 ? -22.86141 -4.39079  84.16841  1.000 52.16294  ? 125 GLU F O   1 
ATOM   7186 C  CB  . GLU F 1 145 ? -21.79697 -6.70082  82.08862  1.000 49.30649  ? 125 GLU F CB  1 
ATOM   7187 C  CG  . GLU F 1 145 ? -21.38304 -7.03372  80.64979  1.000 63.54125  ? 125 GLU F CG  1 
ATOM   7188 C  CD  . GLU F 1 145 ? -21.98926 -8.32260  80.11769  1.000 78.01589  ? 125 GLU F CD  1 
ATOM   7189 O  OE1 . GLU F 1 145 ? -21.86438 -9.37014  80.78484  1.000 78.31589  ? 125 GLU F OE1 1 
ATOM   7190 O  OE2 . GLU F 1 145 ? -22.59935 -8.28093  79.02788  1.000 74.45481  ? 125 GLU F OE2 1 
ATOM   7191 N  N   . THR F 1 146 ? -20.87389 -5.21084  84.83681  1.000 47.74325  ? 126 THR F N   1 
ATOM   7192 C  CA  . THR F 1 146 ? -21.09749 -4.83482  86.22770  1.000 54.14903  ? 126 THR F CA  1 
ATOM   7193 C  C   . THR F 1 146 ? -21.11235 -3.32101  86.39014  1.000 54.94443  ? 126 THR F C   1 
ATOM   7194 O  O   . THR F 1 146 ? -21.91946 -2.77914  87.15452  1.000 57.48923  ? 126 THR F O   1 
ATOM   7195 C  CB  . THR F 1 146 ? -20.01778 -5.45592  87.11731  1.000 49.50369  ? 126 THR F CB  1 
ATOM   7196 O  OG1 . THR F 1 146 ? -19.93485 -6.86410  86.86348  1.000 48.47382  ? 126 THR F OG1 1 
ATOM   7197 C  CG2 . THR F 1 146 ? -20.33783 -5.23360  88.59004  1.000 42.58622  ? 126 THR F CG2 1 
ATOM   7198 N  N   . ALA F 1 147 ? -20.22865 -2.61881  85.67592  1.000 52.23920  ? 127 ALA F N   1 
ATOM   7199 C  CA  . ALA F 1 147 ? -20.22044 -1.16288  85.75241  1.000 52.07951  ? 127 ALA F CA  1 
ATOM   7200 C  C   . ALA F 1 147 ? -21.46766 -0.57302  85.10789  1.000 52.94712  ? 127 ALA F C   1 
ATOM   7201 O  O   . ALA F 1 147 ? -22.00229 0.43489   85.58518  1.000 55.40403  ? 127 ALA F O   1 
ATOM   7202 C  CB  . ALA F 1 147 ? -18.95591 -0.60874  85.09725  1.000 42.06541  ? 127 ALA F CB  1 
ATOM   7203 N  N   . ALA F 1 148 ? -21.94872 -1.18929  84.02533  1.000 54.27281  ? 128 ALA F N   1 
ATOM   7204 C  CA  . ALA F 1 148 ? -23.17934 -0.71570  83.40006  1.000 58.30893  ? 128 ALA F CA  1 
ATOM   7205 C  C   . ALA F 1 148 ? -24.38429 -0.93158  84.31096  1.000 63.54253  ? 128 ALA F C   1 
ATOM   7206 O  O   . ALA F 1 148 ? -25.24948 -0.05441  84.42155  1.000 57.84676  ? 128 ALA F O   1 
ATOM   7207 C  CB  . ALA F 1 148 ? -23.38619 -1.41042  82.05439  1.000 52.19737  ? 128 ALA F CB  1 
ATOM   7208 N  N   . GLN F 1 149 ? -24.45889 -2.08986  84.97517  1.000 60.41702  ? 129 GLN F N   1 
ATOM   7209 C  CA  . GLN F 1 149 ? -25.57583 -2.34678  85.88121  1.000 57.87497  ? 129 GLN F CA  1 
ATOM   7210 C  C   . GLN F 1 149 ? -25.54932 -1.42070  87.09242  1.000 61.45367  ? 129 GLN F C   1 
ATOM   7211 O  O   . GLN F 1 149 ? -26.60088 -1.14080  87.67926  1.000 51.82371  ? 129 GLN F O   1 
ATOM   7212 C  CB  . GLN F 1 149 ? -25.56738 -3.80696  86.33526  1.000 57.57928  ? 129 GLN F CB  1 
ATOM   7213 C  CG  . GLN F 1 149 ? -26.75104 -4.62576  85.83129  1.000 63.05814  ? 129 GLN F CG  1 
ATOM   7214 C  CD  . GLN F 1 149 ? -26.75794 -4.77358  84.32204  1.000 82.90285  ? 129 GLN F CD  1 
ATOM   7215 O  OE1 . GLN F 1 149 ? -25.90159 -5.44890  83.74926  1.000 76.33025  ? 129 GLN F OE1 1 
ATOM   7216 N  NE2 . GLN F 1 149 ? -27.72357 -4.13563  83.66829  1.000 69.34738  ? 129 GLN F NE2 1 
ATOM   7217 N  N   . ALA F 1 150 ? -24.37113 -0.93493  87.47945  1.000 57.18486  ? 130 ALA F N   1 
ATOM   7218 C  CA  . ALA F 1 150 ? -24.24533 0.00346   88.58730  1.000 58.91382  ? 130 ALA F CA  1 
ATOM   7219 C  C   . ALA F 1 150 ? -24.59763 1.43344   88.19473  1.000 59.11634  ? 130 ALA F C   1 
ATOM   7220 O  O   . ALA F 1 150 ? -24.38198 2.35045   88.99498  1.000 64.23518  ? 130 ALA F O   1 
ATOM   7221 C  CB  . ALA F 1 150 ? -22.82445 -0.04745  89.16014  1.000 56.18321  ? 130 ALA F CB  1 
ATOM   7222 N  N   . GLY F 1 151 ? -25.12615 1.63963   86.99076  1.000 69.02117  ? 131 GLY F N   1 
ATOM   7223 C  CA  . GLY F 1 151 ? -25.50485 2.95782   86.52889  1.000 69.05911  ? 131 GLY F CA  1 
ATOM   7224 C  C   . GLY F 1 151 ? -24.37399 3.80720   85.99699  1.000 63.24635  ? 131 GLY F C   1 
ATOM   7225 O  O   . GLY F 1 151 ? -24.56471 5.01341   85.81109  1.000 66.89703  ? 131 GLY F O   1 
ATOM   7226 N  N   . GLY F 1 152 ? -23.20413 3.22486   85.74439  1.000 63.60017  ? 132 GLY F N   1 
ATOM   7227 C  CA  . GLY F 1 152 ? -22.07942 4.00468   85.25850  1.000 59.07608  ? 132 GLY F CA  1 
ATOM   7228 C  C   . GLY F 1 152 ? -22.17693 4.27749   83.76554  1.000 63.90940  ? 132 GLY F C   1 
ATOM   7229 O  O   . GLY F 1 152 ? -22.60301 3.43156   82.98006  1.000 65.05235  ? 132 GLY F O   1 
ATOM   7230 N  N   . ASP F 1 153 ? -21.76223 5.48373   83.37961  1.000 57.42453  ? 133 ASP F N   1 
ATOM   7231 C  CA  . ASP F 1 153 ? -21.73900 5.89719   81.98281  1.000 59.67438  ? 133 ASP F CA  1 
ATOM   7232 C  C   . ASP F 1 153 ? -20.37328 5.72504   81.33123  1.000 56.99034  ? 133 ASP F C   1 
ATOM   7233 O  O   . ASP F 1 153 ? -20.26294 5.88733   80.11225  1.000 55.69606  ? 133 ASP F O   1 
ATOM   7234 C  CB  . ASP F 1 153 ? -22.18615 7.35691   81.85175  1.000 62.28425  ? 133 ASP F CB  1 
ATOM   7235 C  CG  . ASP F 1 153 ? -21.34141 8.30404   82.68537  1.000 60.62480  ? 133 ASP F CG  1 
ATOM   7236 O  OD1 . ASP F 1 153 ? -20.67866 7.83170   83.63259  1.000 62.26871  ? 133 ASP F OD1 1 
ATOM   7237 O  OD2 . ASP F 1 153 ? -21.34064 9.52131   82.39801  1.000 67.14348  ? 133 ASP F OD2 1 
ATOM   7238 N  N   . ALA F 1 154 ? -19.33812 5.40703   82.10462  1.000 51.56204  ? 134 ALA F N   1 
ATOM   7239 C  CA  . ALA F 1 154 ? -18.00279 5.23212   81.55428  1.000 50.90453  ? 134 ALA F CA  1 
ATOM   7240 C  C   . ALA F 1 154 ? -17.18726 4.34816   82.48635  1.000 48.96843  ? 134 ALA F C   1 
ATOM   7241 O  O   . ALA F 1 154 ? -17.41837 4.31580   83.69771  1.000 44.82387  ? 134 ALA F O   1 
ATOM   7242 C  CB  . ALA F 1 154 ? -17.29955 6.57637   81.34519  1.000 52.48972  ? 134 ALA F CB  1 
ATOM   7243 N  N   . LEU F 1 155 ? -16.23591 3.62469   81.90151  1.000 51.54340  ? 135 LEU F N   1 
ATOM   7244 C  CA  . LEU F 1 155 ? -15.31209 2.77074   82.64060  1.000 40.62727  ? 135 LEU F CA  1 
ATOM   7245 C  C   . LEU F 1 155 ? -13.89809 3.24055   82.32839  1.000 41.84784  ? 135 LEU F C   1 
ATOM   7246 O  O   . LEU F 1 155 ? -13.44597 3.14589   81.18201  1.000 46.64905  ? 135 LEU F O   1 
ATOM   7247 C  CB  . LEU F 1 155 ? -15.50356 1.29911   82.27529  1.000 38.99617  ? 135 LEU F CB  1 
ATOM   7248 C  CG  . LEU F 1 155 ? -14.66138 0.29573   83.06887  1.000 44.90211  ? 135 LEU F CG  1 
ATOM   7249 C  CD1 . LEU F 1 155 ? -14.89106 0.47322   84.56134  1.000 41.64559  ? 135 LEU F CD1 1 
ATOM   7250 C  CD2 . LEU F 1 155 ? -14.96701 -1.13476  82.64554  1.000 42.95307  ? 135 LEU F CD2 1 
ATOM   7251 N  N   . ARG F 1 156 ? -13.21264 3.76125   83.34084  1.000 51.16714  ? 136 ARG F N   1 
ATOM   7252 C  CA  . ARG F 1 156 ? -11.85637 4.26641   83.20417  1.000 44.75367  ? 136 ARG F CA  1 
ATOM   7253 C  C   . ARG F 1 156 ? -10.87619 3.28830   83.83606  1.000 46.13534  ? 136 ARG F C   1 
ATOM   7254 O  O   . ARG F 1 156 ? -11.20252 2.59554   84.80425  1.000 44.89797  ? 136 ARG F O   1 
ATOM   7255 C  CB  . ARG F 1 156 ? -11.71359 5.64270   83.86145  1.000 46.90386  ? 136 ARG F CB  1 
ATOM   7256 C  CG  . ARG F 1 156 ? -12.63252 6.70887   83.28651  1.000 55.99815  ? 136 ARG F CG  1 
ATOM   7257 C  CD  . ARG F 1 156 ? -12.61847 7.96570   84.14180  1.000 56.75108  ? 136 ARG F CD  1 
ATOM   7258 N  NE  . ARG F 1 156 ? -13.41499 9.03595   83.55349  1.000 63.38138  ? 136 ARG F NE  1 
ATOM   7259 C  CZ  . ARG F 1 156 ? -13.62129 10.21656  84.12109  1.000 49.19122  ? 136 ARG F CZ  1 
ATOM   7260 N  NH1 . ARG F 1 156 ? -13.11363 10.51187  85.30659  1.000 54.96767  ? 136 ARG F NH1 1 
ATOM   7261 N  NH2 . ARG F 1 156 ? -14.35659 11.12285  83.48345  1.000 51.55741  ? 136 ARG F NH2 1 
ATOM   7262 N  N   . SER F 1 157 ? -9.66782  3.23750   83.28360  1.000 42.72850  ? 137 SER F N   1 
ATOM   7263 C  CA  . SER F 1 157 ? -8.67385  2.31040   83.80420  1.000 47.03459  ? 137 SER F CA  1 
ATOM   7264 C  C   . SER F 1 157 ? -7.28321  2.81783   83.45473  1.000 53.53142  ? 137 SER F C   1 
ATOM   7265 O  O   . SER F 1 157 ? -7.10466  3.60565   82.52233  1.000 48.30404  ? 137 SER F O   1 
ATOM   7266 C  CB  . SER F 1 157 ? -8.89405  0.89407   83.25845  1.000 55.70167  ? 137 SER F CB  1 
ATOM   7267 O  OG  . SER F 1 157 ? -8.11707  -0.06067  83.96216  1.000 60.75648  ? 137 SER F OG  1 
ATOM   7268 N  N   . GLU F 1 158 ? -6.30214  2.36286   84.23069  1.000 54.55208  ? 138 GLU F N   1 
ATOM   7269 C  CA  . GLU F 1 158 ? -4.89136  2.57268   83.93926  1.000 55.44353  ? 138 GLU F CA  1 
ATOM   7270 C  C   . GLU F 1 158 ? -4.28689  1.23780   83.53587  1.000 58.09909  ? 138 GLU F C   1 
ATOM   7271 O  O   . GLU F 1 158 ? -4.37792  0.26061   84.28611  1.000 64.00498  ? 138 GLU F O   1 
ATOM   7272 C  CB  . GLU F 1 158 ? -4.15045  3.15806   85.14278  1.000 62.21079  ? 138 GLU F CB  1 
ATOM   7273 C  CG  . GLU F 1 158 ? -2.64125  3.24601   84.95106  1.000 64.71712  ? 138 GLU F CG  1 
ATOM   7274 C  CD  . GLU F 1 158 ? -1.94157  3.96145   86.08979  1.000 63.27153  ? 138 GLU F CD  1 
ATOM   7275 O  OE1 . GLU F 1 158 ? -1.99749  5.20878   86.13772  1.000 57.95925  ? 138 GLU F OE1 1 
ATOM   7276 O  OE2 . GLU F 1 158 ? -1.33660  3.27502   86.93932  1.000 63.69018  ? 138 GLU F OE2 1 
ATOM   7277 N  N   . ALA F 1 159 ? -3.68033  1.19657   82.35258  1.000 60.97823  ? 139 ALA F N   1 
ATOM   7278 C  CA  . ALA F 1 159 ? -3.19357  -0.04784  81.77945  1.000 66.48531  ? 139 ALA F CA  1 
ATOM   7279 C  C   . ALA F 1 159 ? -1.71030  0.06225   81.46115  1.000 67.82243  ? 139 ALA F C   1 
ATOM   7280 O  O   . ALA F 1 159 ? -1.17613  1.15212   81.24010  1.000 64.68195  ? 139 ALA F O   1 
ATOM   7281 C  CB  . ALA F 1 159 ? -3.96926  -0.42209  80.50842  1.000 56.05027  ? 139 ALA F CB  1 
ATOM   7282 N  N   . ASN F 1 160 ? -1.05090  -1.09454  81.43913  1.000 72.88772  ? 140 ASN F N   1 
ATOM   7283 C  CA  . ASN F 1 160 ? 0.34103   -1.18362  81.03121  1.000 72.75553  ? 140 ASN F CA  1 
ATOM   7284 C  C   . ASN F 1 160 ? 0.39281   -1.58800  79.56663  1.000 69.64039  ? 140 ASN F C   1 
ATOM   7285 O  O   . ASN F 1 160 ? -0.01936  -2.70890  79.23126  1.000 72.63596  ? 140 ASN F O   1 
ATOM   7286 C  CB  . ASN F 1 160 ? 1.09100   -2.19673  81.89543  1.000 63.44385  ? 140 ASN F CB  1 
ATOM   7287 C  CG  . ASN F 1 160 ? 2.56954   -2.27951  81.55630  1.000 75.22377  ? 140 ASN F CG  1 
ATOM   7288 O  OD1 . ASN F 1 160 ? 3.06214   -1.57783  80.67264  1.000 75.27315  ? 140 ASN F OD1 1 
ATOM   7289 N  ND2 . ASN F 1 160 ? 3.28885   -3.13402  82.27253  1.000 76.74718  ? 140 ASN F ND2 1 
ATOM   7290 N  N   . PRO F 1 161 ? 0.87112   -0.72569  78.66317  1.000 69.25488  ? 141 PRO F N   1 
ATOM   7291 C  CA  . PRO F 1 161 ? 0.95594   -1.11961  77.24679  1.000 71.76441  ? 141 PRO F CA  1 
ATOM   7292 C  C   . PRO F 1 161 ? 1.95244   -2.23340  76.98248  1.000 76.09972  ? 141 PRO F C   1 
ATOM   7293 O  O   . PRO F 1 161 ? 1.92329   -2.81972  75.89397  1.000 72.98773  ? 141 PRO F O   1 
ATOM   7294 C  CB  . PRO F 1 161 ? 1.36625   0.18079   76.54018  1.000 73.85081  ? 141 PRO F CB  1 
ATOM   7295 C  CG  . PRO F 1 161 ? 1.98193   1.01994   77.60982  1.000 77.28010  ? 141 PRO F CG  1 
ATOM   7296 C  CD  . PRO F 1 161 ? 1.26778   0.67543   78.87749  1.000 71.61890  ? 141 PRO F CD  1 
ATOM   7297 N  N   . ASP F 1 162 ? 2.83318   -2.54609  77.93340  1.000 82.00545  ? 142 ASP F N   1 
ATOM   7298 C  CA  . ASP F 1 162 ? 3.76078   -3.65690  77.76077  1.000 77.20697  ? 142 ASP F CA  1 
ATOM   7299 C  C   . ASP F 1 162 ? 3.08008   -5.01246  77.90692  1.000 73.53425  ? 142 ASP F C   1 
ATOM   7300 O  O   . ASP F 1 162 ? 3.63585   -6.02262  77.45862  1.000 81.53105  ? 142 ASP F O   1 
ATOM   7301 C  CB  . ASP F 1 162 ? 4.92290   -3.53208  78.75328  1.000 82.74825  ? 142 ASP F CB  1 
ATOM   7302 C  CG  . ASP F 1 162 ? 5.90156   -2.42652  78.37023  1.000 93.19578  ? 142 ASP F CG  1 
ATOM   7303 O  OD1 . ASP F 1 162 ? 5.60485   -1.24546  78.64452  1.000 96.31309  ? 142 ASP F OD1 1 
ATOM   7304 O  OD2 . ASP F 1 162 ? 6.95979   -2.74371  77.78840  1.000 98.26086  ? 142 ASP F OD2 1 
ATOM   7305 N  N   . LEU F 1 163 ? 1.89895   -5.06079  78.52617  1.000 70.56370  ? 143 LEU F N   1 
ATOM   7306 C  CA  . LEU F 1 163 ? 1.05847   -6.25861  78.49792  1.000 76.92856  ? 143 LEU F CA  1 
ATOM   7307 C  C   . LEU F 1 163 ? 0.30689   -6.24345  77.17058  1.000 72.71249  ? 143 LEU F C   1 
ATOM   7308 O  O   . LEU F 1 163 ? -0.83688  -5.79051  77.06905  1.000 69.02190  ? 143 LEU F O   1 
ATOM   7309 C  CB  . LEU F 1 163 ? 0.10572   -6.29465  79.68570  1.000 79.43002  ? 143 LEU F CB  1 
ATOM   7310 C  CG  . LEU F 1 163 ? 0.62499   -6.84079  81.02099  1.000 85.02962  ? 143 LEU F CG  1 
ATOM   7311 C  CD1 . LEU F 1 163 ? 1.58194   -5.87577  81.70746  1.000 75.20021  ? 143 LEU F CD1 1 
ATOM   7312 C  CD2 . LEU F 1 163 ? -0.53412  -7.18978  81.93576  1.000 79.48932  ? 143 LEU F CD2 1 
ATOM   7313 N  N   . SER F 1 164 ? 0.99766   -6.71529  76.12574  1.000 71.02683  ? 144 SER F N   1 
ATOM   7314 C  CA  . SER F 1 164 ? 0.49791   -6.57391  74.76078  1.000 70.76028  ? 144 SER F CA  1 
ATOM   7315 C  C   . SER F 1 164 ? -0.84762  -7.26633  74.58151  1.000 65.67932  ? 144 SER F C   1 
ATOM   7316 O  O   . SER F 1 164 ? -1.75841  -6.71127  73.95562  1.000 60.24773  ? 144 SER F O   1 
ATOM   7317 C  CB  . SER F 1 164 ? 1.52868   -7.12243  73.77162  1.000 66.78485  ? 144 SER F CB  1 
ATOM   7318 O  OG  . SER F 1 164 ? 1.81448   -8.48622  74.03263  1.000 72.25197  ? 144 SER F OG  1 
ATOM   7319 N  N   . ALA F 1 165 ? -0.99386  -8.47669  75.12567  1.000 58.75959  ? 145 ALA F N   1 
ATOM   7320 C  CA  . ALA F 1 165 ? -2.26179  -9.19169  75.01418  1.000 68.11753  ? 145 ALA F CA  1 
ATOM   7321 C  C   . ALA F 1 165 ? -3.39071  -8.41682  75.68439  1.000 67.04648  ? 145 ALA F C   1 
ATOM   7322 O  O   . ALA F 1 165 ? -4.45692  -8.21343  75.09180  1.000 62.97076  ? 145 ALA F O   1 
ATOM   7323 C  CB  . ALA F 1 165 ? -2.12965  -10.58925 75.61907  1.000 62.92860  ? 145 ALA F CB  1 
ATOM   7324 N  N   . THR F 1 166 ? -3.16735  -7.96514  76.92149  1.000 63.50471  ? 146 THR F N   1 
ATOM   7325 C  CA  . THR F 1 166 ? -4.19468  -7.21332  77.63558  1.000 61.94596  ? 146 THR F CA  1 
ATOM   7326 C  C   . THR F 1 166 ? -4.47304  -5.87547  76.96113  1.000 53.39016  ? 146 THR F C   1 
ATOM   7327 O  O   . THR F 1 166 ? -5.62602  -5.43501  76.90027  1.000 57.06667  ? 146 THR F O   1 
ATOM   7328 C  CB  . THR F 1 166 ? -3.77450  -7.00623  79.09114  1.000 55.90817  ? 146 THR F CB  1 
ATOM   7329 O  OG1 . THR F 1 166 ? -3.50694  -8.27751  79.69575  1.000 59.08844  ? 146 THR F OG1 1 
ATOM   7330 C  CG2 . THR F 1 166 ? -4.87250  -6.30210  79.87468  1.000 51.32710  ? 146 THR F CG2 1 
ATOM   7331 N  N   . ARG F 1 167 ? -3.43399  -5.22011  76.43996  1.000 57.10985  ? 147 ARG F N   1 
ATOM   7332 C  CA  . ARG F 1 167 ? -3.62780  -3.93937  75.76667  1.000 57.89835  ? 147 ARG F CA  1 
ATOM   7333 C  C   . ARG F 1 167 ? -4.47607  -4.10264  74.50866  1.000 57.83914  ? 147 ARG F C   1 
ATOM   7334 O  O   . ARG F 1 167 ? -5.40281  -3.31895  74.26190  1.000 58.72011  ? 147 ARG F O   1 
ATOM   7335 C  CB  . ARG F 1 167 ? -2.27072  -3.31666  75.43347  1.000 51.87000  ? 147 ARG F CB  1 
ATOM   7336 C  CG  . ARG F 1 167 ? -2.35742  -1.92984  74.81912  1.000 55.96413  ? 147 ARG F CG  1 
ATOM   7337 C  CD  . ARG F 1 167 ? -2.97119  -0.93539  75.78961  1.000 52.24431  ? 147 ARG F CD  1 
ATOM   7338 N  NE  . ARG F 1 167 ? -3.18769  0.36312   75.16446  1.000 49.70531  ? 147 ARG F NE  1 
ATOM   7339 C  CZ  . ARG F 1 167 ? -4.30289  0.71495   74.53939  1.000 54.27871  ? 147 ARG F CZ  1 
ATOM   7340 N  NH1 . ARG F 1 167 ? -5.32902  -0.11376  74.43780  1.000 49.77523  ? 147 ARG F NH1 1 
ATOM   7341 N  NH2 . ARG F 1 167 ? -4.39134  1.92912   74.00377  1.000 59.19314  ? 147 ARG F NH2 1 
ATOM   7342 N  N   . SER F 1 168 ? -4.17329  -5.12235  73.69905  1.000 59.17203  ? 148 SER F N   1 
ATOM   7343 C  CA  . SER F 1 168 ? -4.97836  -5.38396  72.51021  1.000 64.63301  ? 148 SER F CA  1 
ATOM   7344 C  C   . SER F 1 168 ? -6.40188  -5.77287  72.88482  1.000 51.15804  ? 148 SER F C   1 
ATOM   7345 O  O   . SER F 1 168 ? -7.35880  -5.35422  72.22541  1.000 49.37234  ? 148 SER F O   1 
ATOM   7346 C  CB  . SER F 1 168 ? -4.32996  -6.47652  71.65889  1.000 53.29469  ? 148 SER F CB  1 
ATOM   7347 O  OG  . SER F 1 168 ? -3.16841  -5.99360  71.00698  1.000 62.12071  ? 148 SER F OG  1 
ATOM   7348 N  N   . LEU F 1 169 ? -6.56205  -6.57152  73.94274  1.000 52.99876  ? 149 LEU F N   1 
ATOM   7349 C  CA  . LEU F 1 169 ? -7.89713  -6.94794  74.39430  1.000 54.71223  ? 149 LEU F CA  1 
ATOM   7350 C  C   . LEU F 1 169 ? -8.70292  -5.72441  74.81557  1.000 54.17460  ? 149 LEU F C   1 
ATOM   7351 O  O   . LEU F 1 169 ? -9.89790  -5.62414  74.51407  1.000 52.42088  ? 149 LEU F O   1 
ATOM   7352 C  CB  . LEU F 1 169 ? -7.78403  -7.95223  75.54172  1.000 51.88483  ? 149 LEU F CB  1 
ATOM   7353 C  CG  . LEU F 1 169 ? -9.05668  -8.39305  76.26339  1.000 49.62640  ? 149 LEU F CG  1 
ATOM   7354 C  CD1 . LEU F 1 169 ? -10.07751 -8.94221  75.28248  1.000 56.81166  ? 149 LEU F CD1 1 
ATOM   7355 C  CD2 . LEU F 1 169 ? -8.71491  -9.42907  77.32263  1.000 55.63562  ? 149 LEU F CD2 1 
ATOM   7356 N  N   . LEU F 1 170 ? -8.06220  -4.77894  75.50628  1.000 52.76808  ? 150 LEU F N   1 
ATOM   7357 C  CA  . LEU F 1 170 ? -8.74510  -3.54830  75.89169  1.000 56.08058  ? 150 LEU F CA  1 
ATOM   7358 C  C   . LEU F 1 170 ? -9.10249  -2.70948  74.67180  1.000 53.83181  ? 150 LEU F C   1 
ATOM   7359 O  O   . LEU F 1 170 ? -10.19399 -2.13171  74.60713  1.000 51.53816  ? 150 LEU F O   1 
ATOM   7360 C  CB  . LEU F 1 170 ? -7.87297  -2.74746  76.85698  1.000 53.87111  ? 150 LEU F CB  1 
ATOM   7361 C  CG  . LEU F 1 170 ? -7.69368  -3.34864  78.25106  1.000 53.95687  ? 150 LEU F CG  1 
ATOM   7362 C  CD1 . LEU F 1 170 ? -6.44855  -2.79393  78.92395  1.000 46.36168  ? 150 LEU F CD1 1 
ATOM   7363 C  CD2 . LEU F 1 170 ? -8.92483  -3.08073  79.09996  1.000 52.12107  ? 150 LEU F CD2 1 
ATOM   7364 N  N   . ASP F 1 171 ? -8.19672  -2.63234  73.69392  1.000 54.32198  ? 151 ASP F N   1 
ATOM   7365 C  CA  . ASP F 1 171 ? -8.48167  -1.86139  72.48694  1.000 54.49546  ? 151 ASP F CA  1 
ATOM   7366 C  C   . ASP F 1 171 ? -9.64221  -2.46288  71.70353  1.000 48.25933  ? 151 ASP F C   1 
ATOM   7367 O  O   . ASP F 1 171 ? -10.47149 -1.73014  71.15363  1.000 44.79721  ? 151 ASP F O   1 
ATOM   7368 C  CB  . ASP F 1 171 ? -7.23231  -1.77529  71.61012  1.000 57.60161  ? 151 ASP F CB  1 
ATOM   7369 C  CG  . ASP F 1 171 ? -7.47812  -1.02857  70.31172  1.000 53.85604  ? 151 ASP F CG  1 
ATOM   7370 O  OD1 . ASP F 1 171 ? -7.72783  0.19396   70.36285  1.000 62.52151  ? 151 ASP F OD1 1 
ATOM   7371 O  OD2 . ASP F 1 171 ? -7.41687  -1.66446  69.23857  1.000 59.85460  ? 151 ASP F OD2 1 
ATOM   7372 N  N   . ILE F 1 172 ? -9.71949  -3.79302  71.64410  1.000 49.14909  ? 152 ILE F N   1 
ATOM   7373 C  CA  . ILE F 1 172 ? -10.77032 -4.44708  70.86967  1.000 47.32146  ? 152 ILE F CA  1 
ATOM   7374 C  C   . ILE F 1 172 ? -12.12849 -4.24944  71.53127  1.000 49.17407  ? 152 ILE F C   1 
ATOM   7375 O  O   . ILE F 1 172 ? -13.15101 -4.09486  70.85099  1.000 41.66351  ? 152 ILE F O   1 
ATOM   7376 C  CB  . ILE F 1 172 ? -10.43404 -5.93895  70.68512  1.000 42.28104  ? 152 ILE F CB  1 
ATOM   7377 C  CG1 . ILE F 1 172 ? -9.20478  -6.09148  69.78221  1.000 48.24963  ? 152 ILE F CG1 1 
ATOM   7378 C  CG2 . ILE F 1 172 ? -11.62347 -6.70046  70.10773  1.000 40.23867  ? 152 ILE F CG2 1 
ATOM   7379 C  CD1 . ILE F 1 172 ? -8.50831  -7.43067  69.91391  1.000 47.17083  ? 152 ILE F CD1 1 
ATOM   7380 N  N   . LEU F 1 173 ? -12.16179 -4.23105  72.86218  1.000 50.65540  ? 153 LEU F N   1 
ATOM   7381 C  CA  . LEU F 1 173 ? -13.41517 -4.09160  73.59255  1.000 44.64164  ? 153 LEU F CA  1 
ATOM   7382 C  C   . LEU F 1 173 ? -13.92097 -2.65323  73.65565  1.000 42.74852  ? 153 LEU F C   1 
ATOM   7383 O  O   . LEU F 1 173 ? -14.95071 -2.40311  74.29274  1.000 43.66860  ? 153 LEU F O   1 
ATOM   7384 C  CB  . LEU F 1 173 ? -13.25886 -4.65207  75.00914  1.000 37.42380  ? 153 LEU F CB  1 
ATOM   7385 C  CG  . LEU F 1 173 ? -13.10642 -6.17548  75.08513  1.000 48.07421  ? 153 LEU F CG  1 
ATOM   7386 C  CD1 . LEU F 1 173 ? -13.22182 -6.65885  76.52391  1.000 45.32102  ? 153 LEU F CD1 1 
ATOM   7387 C  CD2 . LEU F 1 173 ? -14.12559 -6.88338  74.19015  1.000 37.51577  ? 153 LEU F CD2 1 
ATOM   7388 N  N   . GLY F 1 174 ? -13.23911 -1.70851  73.01598  1.000 43.93950  ? 154 GLY F N   1 
ATOM   7389 C  CA  . GLY F 1 174 ? -13.71737 -0.34496  72.93329  1.000 52.38813  ? 154 GLY F CA  1 
ATOM   7390 C  C   . GLY F 1 174 ? -13.06219 0.65070   73.86434  1.000 50.06855  ? 154 GLY F C   1 
ATOM   7391 O  O   . GLY F 1 174 ? -13.50352 1.80456   73.90991  1.000 46.83893  ? 154 GLY F O   1 
ATOM   7392 N  N   . PHE F 1 175 ? -12.03268 0.24996   74.60725  1.000 50.06647  ? 155 PHE F N   1 
ATOM   7393 C  CA  . PHE F 1 175 ? -11.32233 1.17297   75.48452  1.000 56.80731  ? 155 PHE F CA  1 
ATOM   7394 C  C   . PHE F 1 175 ? -10.46087 2.11031   74.64574  1.000 57.52257  ? 155 PHE F C   1 
ATOM   7395 O  O   . PHE F 1 175 ? -9.55716  1.66254   73.93117  1.000 62.73414  ? 155 PHE F O   1 
ATOM   7396 C  CB  . PHE F 1 175 ? -10.47138 0.40628   76.49512  1.000 54.72440  ? 155 PHE F CB  1 
ATOM   7397 C  CG  . PHE F 1 175 ? -11.27025 -0.24676  77.58774  1.000 55.45411  ? 155 PHE F CG  1 
ATOM   7398 C  CD1 . PHE F 1 175 ? -11.88038 -1.47343  77.38148  1.000 54.12984  ? 155 PHE F CD1 1 
ATOM   7399 C  CD2 . PHE F 1 175 ? -11.41429 0.36821   78.82223  1.000 58.95157  ? 155 PHE F CD2 1 
ATOM   7400 C  CE1 . PHE F 1 175 ? -12.61793 -2.07551  78.38423  1.000 50.16366  ? 155 PHE F CE1 1 
ATOM   7401 C  CE2 . PHE F 1 175 ? -12.15092 -0.22840  79.83019  1.000 47.48758  ? 155 PHE F CE2 1 
ATOM   7402 C  CZ  . PHE F 1 175 ? -12.75299 -1.45183  79.61036  1.000 51.92473  ? 155 PHE F CZ  1 
ATOM   7403 N  N   . VAL F 1 176 ? -10.74480 3.40744   74.73283  1.000 59.81643  ? 156 VAL F N   1 
ATOM   7404 C  CA  . VAL F 1 176 ? -10.06864 4.42937   73.94225  1.000 52.22698  ? 156 VAL F CA  1 
ATOM   7405 C  C   . VAL F 1 176 ? -9.07336  5.16328   74.82858  1.000 62.38610  ? 156 VAL F C   1 
ATOM   7406 O  O   . VAL F 1 176 ? -9.40479  5.56285   75.95234  1.000 58.18455  ? 156 VAL F O   1 
ATOM   7407 C  CB  . VAL F 1 176 ? -11.08056 5.41027   73.32301  1.000 56.48596  ? 156 VAL F CB  1 
ATOM   7408 C  CG1 . VAL F 1 176 ? -10.40184 6.71747   72.93242  1.000 57.32899  ? 156 VAL F CG1 1 
ATOM   7409 C  CG2 . VAL F 1 176 ? -11.75123 4.78087   72.11652  1.000 63.17790  ? 156 VAL F CG2 1 
ATOM   7410 N  N   . GLN F 1 177 ? -7.85403  5.33955   74.32452  1.000 65.47087  ? 157 GLN F N   1 
ATOM   7411 C  CA  . GLN F 1 177 ? -6.86450  6.17276   74.99085  1.000 61.81066  ? 157 GLN F CA  1 
ATOM   7412 C  C   . GLN F 1 177 ? -7.11220  7.63691   74.64845  1.000 72.69726  ? 157 GLN F C   1 
ATOM   7413 O  O   . GLN F 1 177 ? -7.27029  7.99240   73.47610  1.000 73.99267  ? 157 GLN F O   1 
ATOM   7414 C  CB  . GLN F 1 177 ? -5.45247  5.75896   74.57925  1.000 64.32558  ? 157 GLN F CB  1 
ATOM   7415 C  CG  . GLN F 1 177 ? -4.41031  6.82813   74.82948  1.000 67.60915  ? 157 GLN F CG  1 
ATOM   7416 C  CD  . GLN F 1 177 ? -2.99185  6.30346   74.74156  1.000 74.97386  ? 157 GLN F CD  1 
ATOM   7417 O  OE1 . GLN F 1 177 ? -2.76245  5.09345   74.72634  1.000 68.04122  ? 157 GLN F OE1 1 
ATOM   7418 N  NE2 . GLN F 1 177 ? -2.02831  7.21565   74.68998  1.000 81.20729  ? 157 GLN F NE2 1 
ATOM   7419 N  N   . HIS F 1 178 ? -7.14585  8.48529   75.67411  1.000 85.89068  ? 158 HIS F N   1 
ATOM   7420 C  CA  . HIS F 1 178 ? -7.45300  9.90033   75.50739  1.000 81.02650  ? 158 HIS F CA  1 
ATOM   7421 C  C   . HIS F 1 178 ? -6.21064  10.78039  75.46130  1.000 89.38572  ? 158 HIS F C   1 
ATOM   7422 O  O   . HIS F 1 178 ? -6.13074  11.68452  74.62342  1.000 83.73025  ? 158 HIS F O   1 
ATOM   7423 C  CB  . HIS F 1 178 ? -8.37255  10.36916  76.63973  1.000 84.54088  ? 158 HIS F CB  1 
ATOM   7424 C  CG  . HIS F 1 178 ? -9.27580  11.50054  76.25864  1.000 89.66274  ? 158 HIS F CG  1 
ATOM   7425 N  ND1 . HIS F 1 178 ? -9.22333  12.73463  76.87104  1.000 80.24267  ? 158 HIS F ND1 1 
ATOM   7426 C  CD2 . HIS F 1 178 ? -10.25832 11.58255  75.33019  1.000 85.62350  ? 158 HIS F CD2 1 
ATOM   7427 C  CE1 . HIS F 1 178 ? -10.13339 13.52845  76.33535  1.000 76.06800  ? 158 HIS F CE1 1 
ATOM   7428 N  NE2 . HIS F 1 178 ? -10.77485 12.85382  75.39798  1.000 80.97265  ? 158 HIS F NE2 1 
ATOM   7429 N  N   . GLY F 1 179 ? -5.23781  10.53394  76.33728  1.000 88.93958  ? 159 GLY F N   1 
ATOM   7430 C  CA  . GLY F 1 179 ? -4.04118  11.33932  76.40337  1.000 92.67968  ? 159 GLY F CA  1 
ATOM   7431 C  C   . GLY F 1 179 ? -2.80758  10.59719  75.92925  1.000 95.34617  ? 159 GLY F C   1 
ATOM   7432 O  O   . GLY F 1 179 ? -2.87483  9.43688   75.51565  1.000 92.27066  ? 159 GLY F O   1 
ATOM   7433 N  N   . PRO F 1 180 ? -1.65284  11.25760  75.97371  1.000 94.75302  ? 160 PRO F N   1 
ATOM   7434 C  CA  . PRO F 1 180 ? -0.41169  10.61145  75.53066  1.000 93.31884  ? 160 PRO F CA  1 
ATOM   7435 C  C   . PRO F 1 180 ? 0.05201   9.55478   76.52360  1.000 96.34601  ? 160 PRO F C   1 
ATOM   7436 O  O   . PRO F 1 180 ? -0.46186  9.42179   77.63615  1.000 96.52996  ? 160 PRO F O   1 
ATOM   7437 C  CB  . PRO F 1 180 ? 0.59055   11.76912  75.44300  1.000 93.97707  ? 160 PRO F CB  1 
ATOM   7438 C  CG  . PRO F 1 180 ? -0.24392  13.02028  75.46282  1.000 92.72259  ? 160 PRO F CG  1 
ATOM   7439 C  CD  . PRO F 1 180 ? -1.44988  12.68186  76.28019  1.000 94.74324  ? 160 PRO F CD  1 
ATOM   7440 N  N   . THR F 1 181 ? 1.05537   8.79279   76.09573  1.000 91.62352  ? 161 THR F N   1 
ATOM   7441 C  CA  . THR F 1 181 ? 1.63166   7.74794   76.93159  1.000 88.93163  ? 161 THR F CA  1 
ATOM   7442 C  C   . THR F 1 181 ? 2.60041   8.34926   77.94215  1.000 92.70572  ? 161 THR F C   1 
ATOM   7443 O  O   . THR F 1 181 ? 3.40647   9.22137   77.60567  1.000 92.47524  ? 161 THR F O   1 
ATOM   7444 C  CB  . THR F 1 181 ? 2.35170   6.70974   76.06983  1.000 95.30461  ? 161 THR F CB  1 
ATOM   7445 O  OG1 . THR F 1 181 ? 1.42814   6.13602   75.13690  1.000 92.24457  ? 161 THR F OG1 1 
ATOM   7446 C  CG2 . THR F 1 181 ? 2.93147   5.60374   76.92994  1.000 91.90042  ? 161 THR F CG2 1 
ATOM   7447 N  N   . LEU F 1 182 ? 2.50492   7.88678   79.18828  1.000 92.09903  ? 162 LEU F N   1 
ATOM   7448 C  CA  . LEU F 1 182 ? 3.30309   8.39804   80.29365  1.000 86.48340  ? 162 LEU F CA  1 
ATOM   7449 C  C   . LEU F 1 182 ? 4.30656   7.34401   80.74284  1.000 88.56250  ? 162 LEU F C   1 
ATOM   7450 O  O   . LEU F 1 182 ? 4.00473   6.14689   80.74458  1.000 96.43092  ? 162 LEU F O   1 
ATOM   7451 C  CB  . LEU F 1 182 ? 2.41889   8.80809   81.47620  1.000 88.03658  ? 162 LEU F CB  1 
ATOM   7452 C  CG  . LEU F 1 182 ? 1.24222   9.75487   81.20957  1.000 92.09954  ? 162 LEU F CG  1 
ATOM   7453 C  CD1 . LEU F 1 182 ? -0.01136  8.98808   80.79650  1.000 81.31342  ? 162 LEU F CD1 1 
ATOM   7454 C  CD2 . LEU F 1 182 ? 0.95570   10.63452  82.42048  1.000 90.81521  ? 162 LEU F CD2 1 
ATOM   7455 N  N   . SER F 1 183 ? 5.49818   7.79391   81.12688  1.000 91.96844  ? 163 SER F N   1 
ATOM   7456 C  CA  . SER F 1 183 ? 6.54560   6.89055   81.59847  1.000 95.54088  ? 163 SER F CA  1 
ATOM   7457 C  C   . SER F 1 183 ? 6.85282   7.11043   83.07819  1.000 82.80311  ? 163 SER F C   1 
ATOM   7458 O  O   . SER F 1 183 ? 6.52289   8.15328   83.64448  1.000 93.81864  ? 163 SER F O   1 
ATOM   7459 C  CB  . SER F 1 183 ? 7.81890   7.06463   80.76720  1.000 91.23096  ? 163 SER F CB  1 
ATOM   7460 O  OG  . SER F 1 183 ? 7.64688   6.54386   79.46101  1.000 90.21447  ? 163 SER F OG  1 
ATOM   7461 N  N   . ARG F 1 189 ? 5.79428   2.22583   82.23901  1.000 81.70293  ? 169 ARG F N   1 
ATOM   7462 C  CA  . ARG F 1 189 ? 4.97097   2.87021   81.22324  1.000 87.15834  ? 169 ARG F CA  1 
ATOM   7463 C  C   . ARG F 1 189 ? 3.49099   2.56828   81.46968  1.000 84.92797  ? 169 ARG F C   1 
ATOM   7464 O  O   . ARG F 1 189 ? 3.14561   1.49295   81.96288  1.000 77.44956  ? 169 ARG F O   1 
ATOM   7465 C  CB  . ARG F 1 189 ? 5.39984   2.41086   79.82757  1.000 87.84042  ? 169 ARG F CB  1 
ATOM   7466 C  CG  . ARG F 1 189 ? 4.91852   3.29127   78.69138  1.000 92.01839  ? 169 ARG F CG  1 
ATOM   7467 C  CD  . ARG F 1 189 ? 5.70244   2.99578   77.41887  1.000 85.05843  ? 169 ARG F CD  1 
ATOM   7468 N  NE  . ARG F 1 189 ? 5.80711   1.56137   77.18235  1.000 90.49025  ? 169 ARG F NE  1 
ATOM   7469 C  CZ  . ARG F 1 189 ? 5.14004   0.90133   76.24481  1.000 88.34163  ? 169 ARG F CZ  1 
ATOM   7470 N  NH1 . ARG F 1 189 ? 4.34289   1.52442   75.39138  1.000 83.89933  ? 169 ARG F NH1 1 
ATOM   7471 N  NH2 . ARG F 1 189 ? 5.27783   -0.41784  76.15882  1.000 79.08589  ? 169 ARG F NH2 1 
ATOM   7472 N  N   . ARG F 1 190 ? 2.62188   3.52092   81.13364  1.000 82.53852  ? 170 ARG F N   1 
ATOM   7473 C  CA  . ARG F 1 190 ? 1.20457   3.39096   81.44282  1.000 78.64270  ? 170 ARG F CA  1 
ATOM   7474 C  C   . ARG F 1 190 ? 0.39639   4.26208   80.49168  1.000 78.53166  ? 170 ARG F C   1 
ATOM   7475 O  O   . ARG F 1 190 ? 0.90181   5.24685   79.94571  1.000 78.63078  ? 170 ARG F O   1 
ATOM   7476 C  CB  . ARG F 1 190 ? 0.91232   3.78616   82.89851  1.000 73.02309  ? 170 ARG F CB  1 
ATOM   7477 C  CG  . ARG F 1 190 ? 0.89206   5.29177   83.13312  1.000 83.81110  ? 170 ARG F CG  1 
ATOM   7478 C  CD  . ARG F 1 190 ? 1.13969   5.65026   84.58909  1.000 86.28110  ? 170 ARG F CD  1 
ATOM   7479 N  NE  . ARG F 1 190 ? 1.22388   7.09424   84.77750  1.000 94.57306  ? 170 ARG F NE  1 
ATOM   7480 C  CZ  . ARG F 1 190 ? 2.35959   7.77882   84.83264  1.000 95.88295  ? 170 ARG F CZ  1 
ATOM   7481 N  NH1 . ARG F 1 190 ? 3.53656   7.17615   84.76287  1.000 88.11702  ? 170 ARG F NH1 1 
ATOM   7482 N  NH2 . ARG F 1 190 ? 2.31479   9.10068   84.97323  1.000 95.69854  ? 170 ARG F NH2 1 
ATOM   7483 N  N   . VAL F 1 191 ? -0.86833  3.88222   80.30120  1.000 75.37651  ? 171 VAL F N   1 
ATOM   7484 C  CA  . VAL F 1 191 ? -1.82424  4.66309   79.52876  1.000 71.96453  ? 171 VAL F CA  1 
ATOM   7485 C  C   . VAL F 1 191 ? -3.14702  4.70142   80.28400  1.000 69.33602  ? 171 VAL F C   1 
ATOM   7486 O  O   . VAL F 1 191 ? -3.46143  3.81922   81.08762  1.000 62.29480  ? 171 VAL F O   1 
ATOM   7487 C  CB  . VAL F 1 191 ? -2.03144  4.10830   78.10027  1.000 74.56334  ? 171 VAL F CB  1 
ATOM   7488 C  CG1 . VAL F 1 191 ? -0.77936  4.30768   77.25575  1.000 80.23901  ? 171 VAL F CG1 1 
ATOM   7489 C  CG2 . VAL F 1 191 ? -2.41790  2.63619   78.14483  1.000 65.92615  ? 171 VAL F CG2 1 
ATOM   7490 N  N   . HIS F 1 192 ? -3.92184  5.75005   80.01718  1.000 61.75395  ? 172 HIS F N   1 
ATOM   7491 C  CA  . HIS F 1 192 ? -5.22898  5.95207   80.63141  1.000 62.48687  ? 172 HIS F CA  1 
ATOM   7492 C  C   . HIS F 1 192 ? -6.30683  5.68228   79.58913  1.000 64.34532  ? 172 HIS F C   1 
ATOM   7493 O  O   . HIS F 1 192 ? -6.38623  6.38667   78.57605  1.000 64.62171  ? 172 HIS F O   1 
ATOM   7494 C  CB  . HIS F 1 192 ? -5.35765  7.36738   81.19654  1.000 65.35924  ? 172 HIS F CB  1 
ATOM   7495 C  CG  . HIS F 1 192 ? -4.57147  7.59242   82.45186  1.000 70.79548  ? 172 HIS F CG  1 
ATOM   7496 N  ND1 . HIS F 1 192 ? -4.36870  6.60371   83.39119  1.000 69.85373  ? 172 HIS F ND1 1 
ATOM   7497 C  CD2 . HIS F 1 192 ? -3.93650  8.69283   82.92126  1.000 71.91719  ? 172 HIS F CD2 1 
ATOM   7498 C  CE1 . HIS F 1 192 ? -3.64460  7.08575   84.38547  1.000 69.33681  ? 172 HIS F CE1 1 
ATOM   7499 N  NE2 . HIS F 1 192 ? -3.36868  8.35095   84.12470  1.000 74.95321  ? 172 HIS F NE2 1 
ATOM   7500 N  N   . LEU F 1 193 ? -7.12948  4.66654   79.83932  1.000 60.05953  ? 173 LEU F N   1 
ATOM   7501 C  CA  . LEU F 1 193 ? -8.13139  4.20401   78.89367  1.000 54.91336  ? 173 LEU F CA  1 
ATOM   7502 C  C   . LEU F 1 193 ? -9.53438  4.49058   79.41275  1.000 57.65193  ? 173 LEU F C   1 
ATOM   7503 O  O   . LEU F 1 193 ? -9.79055  4.46541   80.62140  1.000 55.20643  ? 173 LEU F O   1 
ATOM   7504 C  CB  . LEU F 1 193 ? -7.97920  2.70381   78.62526  1.000 53.46337  ? 173 LEU F CB  1 
ATOM   7505 C  CG  . LEU F 1 193 ? -6.61003  2.24868   78.11737  1.000 54.89432  ? 173 LEU F CG  1 
ATOM   7506 C  CD1 . LEU F 1 193 ? -6.56650  0.73789   77.95650  1.000 51.13099  ? 173 LEU F CD1 1 
ATOM   7507 C  CD2 . LEU F 1 193 ? -6.27339  2.93590   76.80657  1.000 58.22578  ? 173 LEU F CD2 1 
ATOM   7508 N  N   . HIS F 1 194 ? -10.44127 4.75083   78.47337  1.000 56.39630  ? 174 HIS F N   1 
ATOM   7509 C  CA  . HIS F 1 194 ? -11.83821 5.04264   78.76162  1.000 51.95127  ? 174 HIS F CA  1 
ATOM   7510 C  C   . HIS F 1 194 ? -12.71157 4.25767   77.79823  1.000 56.50711  ? 174 HIS F C   1 
ATOM   7511 O  O   . HIS F 1 194 ? -12.44300 4.23931   76.59274  1.000 56.57092  ? 174 HIS F O   1 
ATOM   7512 C  CB  . HIS F 1 194 ? -12.12941 6.54171   78.63273  1.000 52.38051  ? 174 HIS F CB  1 
ATOM   7513 C  CG  . HIS F 1 194 ? -13.56907 6.85855   78.36839  1.000 64.69500  ? 174 HIS F CG  1 
ATOM   7514 N  ND1 . HIS F 1 194 ? -14.10938 6.86981   77.09926  1.000 67.49277  ? 174 HIS F ND1 1 
ATOM   7515 C  CD2 . HIS F 1 194 ? -14.57958 7.18026   79.21010  1.000 63.45133  ? 174 HIS F CD2 1 
ATOM   7516 C  CE1 . HIS F 1 194 ? -15.39140 7.18029   77.17200  1.000 71.71528  ? 174 HIS F CE1 1 
ATOM   7517 N  NE2 . HIS F 1 194 ? -15.70108 7.37616   78.44133  1.000 66.80503  ? 174 HIS F NE2 1 
ATOM   7518 N  N   . LYS F 1 195 ? -13.75102 3.61516   78.32714  1.000 55.17607  ? 175 LYS F N   1 
ATOM   7519 C  CA  . LYS F 1 195 ? -14.73164 2.91200   77.51249  1.000 52.96636  ? 175 LYS F CA  1 
ATOM   7520 C  C   . LYS F 1 195 ? -16.11892 3.43334   77.84892  1.000 52.38959  ? 175 LYS F C   1 
ATOM   7521 O  O   . LYS F 1 195 ? -16.49888 3.47929   79.02252  1.000 52.06599  ? 175 LYS F O   1 
ATOM   7522 C  CB  . LYS F 1 195 ? -14.67015 1.39900   77.73600  1.000 51.44681  ? 175 LYS F CB  1 
ATOM   7523 C  CG  . LYS F 1 195 ? -15.42377 0.59873   76.67879  1.000 50.40353  ? 175 LYS F CG  1 
ATOM   7524 C  CD  . LYS F 1 195 ? -16.33708 -0.44978  77.29024  1.000 50.75365  ? 175 LYS F CD  1 
ATOM   7525 C  CE  . LYS F 1 195 ? -17.11798 -1.16760  76.20079  1.000 53.02256  ? 175 LYS F CE  1 
ATOM   7526 N  NZ  . LYS F 1 195 ? -17.53659 -0.23008  75.11603  1.000 47.78973  ? 175 LYS F NZ  1 
ATOM   7527 N  N   . SER F 1 196 ? -16.86988 3.82076   76.82297  1.000 51.87079  ? 176 SER F N   1 
ATOM   7528 C  CA  . SER F 1 196 ? -18.23245 4.28665   77.03214  1.000 49.61857  ? 176 SER F CA  1 
ATOM   7529 C  C   . SER F 1 196 ? -19.12805 3.13477   77.47227  1.000 58.95782  ? 176 SER F C   1 
ATOM   7530 O  O   . SER F 1 196 ? -18.97118 1.99614   77.02277  1.000 51.07042  ? 176 SER F O   1 
ATOM   7531 C  CB  . SER F 1 196 ? -18.78074 4.91400   75.75041  1.000 48.76847  ? 176 SER F CB  1 
ATOM   7532 O  OG  . SER F 1 196 ? -17.93309 5.94866   75.28819  1.000 67.35051  ? 176 SER F OG  1 
ATOM   7533 N  N   . LEU F 1 197 ? -20.06804 3.43658   78.35876  1.000 54.05035  ? 177 LEU F N   1 
ATOM   7534 C  CA  . LEU F 1 197 ? -21.02011 2.46860   78.87972  1.000 56.91222  ? 177 LEU F CA  1 
ATOM   7535 C  C   . LEU F 1 197 ? -22.43856 2.95580   78.60976  1.000 72.25226  ? 177 LEU F C   1 
ATOM   7536 O  O   . LEU F 1 197 ? -22.65484 4.05043   78.08415  1.000 73.22824  ? 177 LEU F O   1 
ATOM   7537 C  CB  . LEU F 1 197 ? -20.80725 2.24128   80.37840  1.000 53.99397  ? 177 LEU F CB  1 
ATOM   7538 C  CG  . LEU F 1 197 ? -19.43489 1.73701   80.82881  1.000 56.51234  ? 177 LEU F CG  1 
ATOM   7539 C  CD1 . LEU F 1 197 ? -19.41061 1.62214   82.33734  1.000 51.14705  ? 177 LEU F CD1 1 
ATOM   7540 C  CD2 . LEU F 1 197 ? -19.10129 0.40360   80.17890  1.000 53.56895  ? 177 LEU F CD2 1 
ATOM   7541 N  N   . ARG F 1 198 ? -23.41587 2.12955   78.97847  1.000 75.18421  ? 178 ARG F N   1 
ATOM   7542 C  CA  . ARG F 1 198 ? -24.82527 2.51398   78.91414  1.000 80.03188  ? 178 ARG F CA  1 
ATOM   7543 C  C   . ARG F 1 198 ? -25.54399 1.95265   80.13598  1.000 84.32849  ? 178 ARG F C   1 
ATOM   7544 O  O   . ARG F 1 198 ? -25.82055 0.74312   80.20519  1.000 78.23939  ? 178 ARG F O   1 
ATOM   7545 C  CB  . ARG F 1 198 ? -25.47714 2.05237   77.61116  1.000 72.23445  ? 178 ARG F CB  1 
ATOM   7546 C  CG  . ARG F 1 198 ? -26.93982 2.49746   77.35874  1.000 83.10703  ? 178 ARG F CG  1 
ATOM   7547 C  CD  . ARG F 1 198 ? -27.34274 3.90539   77.86520  1.000 88.11462  ? 178 ARG F CD  1 
ATOM   7548 N  NE  . ARG F 1 198 ? -26.28261 4.90849   77.84671  1.000 95.24175  ? 178 ARG F NE  1 
ATOM   7549 C  CZ  . ARG F 1 198 ? -26.44683 6.17732   78.20009  1.000 94.55738  ? 178 ARG F CZ  1 
ATOM   7550 N  NH1 . ARG F 1 198 ? -27.64806 6.67653   78.45642  1.000 96.11118  ? 178 ARG F NH1 1 
ATOM   7551 N  NH2 . ARG F 1 198 ? -25.38033 6.96710   78.29588  1.000 89.49407  ? 178 ARG F NH2 1 
ATOM   7552 N  N   . PRO F 1 199 ? -25.85458 2.80454   81.12991  1.000 83.82138  ? 179 PRO F N   1 
ATOM   7553 C  CA  . PRO F 1 199 ? -26.51547 2.47010   82.39707  1.000 82.43738  ? 179 PRO F CA  1 
ATOM   7554 C  C   . PRO F 1 199 ? -27.83938 1.73242   82.21793  1.000 86.26923  ? 179 PRO F C   1 
ATOM   7555 O  O   . PRO F 1 199 ? -28.31186 1.05280   83.13032  1.000 79.02416  ? 179 PRO F O   1 
ATOM   7556 C  CB  . PRO F 1 199 ? -26.74862 3.84162   83.03738  1.000 80.01159  ? 179 PRO F CB  1 
ATOM   7557 C  CG  . PRO F 1 199 ? -25.68270 4.70386   82.46899  1.000 67.68549  ? 179 PRO F CG  1 
ATOM   7558 C  CD  . PRO F 1 199 ? -25.51584 4.23797   81.05531  1.000 76.36330  ? 179 PRO F CD  1 
HETATM 7559 CL CL  . CL  G 2 .   ? -30.17889 -28.59888 15.35219  1.000 63.78264  ? 201 CL  B CL  1 
HETATM 7560 O  O   . HOH H 3 .   ? 17.67177  -35.45006 37.74756  1.000 47.53724  ? 201 HOH D O   1 
HETATM 7561 O  O   . HOH H 3 .   ? 3.07611   -19.88640 52.32329  1.000 38.25441  ? 202 HOH D O   1 
HETATM 7562 O  O   . HOH H 3 .   ? -8.37132  -37.42879 35.06379  1.000 40.49874  ? 203 HOH D O   1 
HETATM 7563 O  O   . HOH H 3 .   ? 5.74143   -26.33250 30.26096  1.000 33.25898  ? 204 HOH D O   1 
HETATM 7564 O  O   . HOH H 3 .   ? 17.99659  -32.74596 38.00851  1.000 48.17018  ? 205 HOH D O   1 
HETATM 7565 O  O   . HOH H 3 .   ? 6.29378   -22.44343 22.30814  1.000 34.49699  ? 206 HOH D O   1 
HETATM 7566 O  O   . HOH H 3 .   ? -0.63769  -41.13952 35.92555  1.000 31.70819  ? 207 HOH D O   1 
HETATM 7567 O  O   . HOH H 3 .   ? 19.53531  -22.97047 38.79504  1.000 34.22492  ? 208 HOH D O   1 
HETATM 7568 O  O   . HOH H 3 .   ? 15.81124  -16.21622 49.57066  1.000 38.90331  ? 209 HOH D O   1 
HETATM 7569 O  O   . HOH H 3 .   ? -13.25671 -31.77116 46.91190  1.000 34.82917  ? 210 HOH D O   1 
HETATM 7570 O  O   . HOH H 3 .   ? 21.01453  -22.34634 47.76170  1.000 40.11769  ? 211 HOH D O   1 
HETATM 7571 O  O   . HOH H 3 .   ? 4.27049   -27.11759 25.90641  1.000 33.33727  ? 212 HOH D O   1 
HETATM 7572 O  O   . HOH H 3 .   ? 4.64762   -14.69610 30.18250  1.000 41.65921  ? 213 HOH D O   1 
HETATM 7573 O  O   . HOH H 3 .   ? 14.57883  -28.69404 25.29810  1.000 37.35646  ? 214 HOH D O   1 
HETATM 7574 O  O   . HOH H 3 .   ? -1.92627  -24.51625 42.82718  1.000 19.78805  ? 215 HOH D O   1 
HETATM 7575 O  O   . HOH H 3 .   ? 3.191     -45.507   41.931    1.000 43.22853  ? 216 HOH D O   1 
HETATM 7576 O  O   . HOH H 3 .   ? 8.73963   -23.66014 51.01469  1.000 42.93348  ? 217 HOH D O   1 
HETATM 7577 O  O   . HOH H 3 .   ? -2.02820  -39.16494 30.21762  1.000 33.20044  ? 218 HOH D O   1 
HETATM 7578 O  O   . HOH H 3 .   ? 5.43798   -22.36244 40.69201  1.000 24.91483  ? 219 HOH D O   1 
HETATM 7579 O  O   . HOH H 3 .   ? -3.26130  -38.84485 27.78937  1.000 32.00709  ? 220 HOH D O   1 
HETATM 7580 O  O   . HOH H 3 .   ? -7.83380  -36.28975 32.54430  1.000 31.28049  ? 221 HOH D O   1 
HETATM 7581 O  O   . HOH H 3 .   ? 1.11249   -23.28019 49.72825  1.000 39.69463  ? 222 HOH D O   1 
HETATM 7582 O  O   . HOH H 3 .   ? -9.86730  -27.42688 48.83230  1.000 36.53127  ? 223 HOH D O   1 
HETATM 7583 O  O   . HOH H 3 .   ? -4.63774  -20.28027 47.91985  1.000 39.51043  ? 224 HOH D O   1 
HETATM 7584 O  O   . HOH H 3 .   ? 14.48653  -30.87324 48.89094  1.000 39.33241  ? 225 HOH D O   1 
HETATM 7585 O  O   . HOH H 3 .   ? 25.49144  -22.60588 49.07436  1.000 39.73658  ? 226 HOH D O   1 
HETATM 7586 O  O   . HOH H 3 .   ? -3.59988  -43.18037 36.11316  1.000 40.50775  ? 227 HOH D O   1 
HETATM 7587 O  O   . HOH H 3 .   ? 12.06056  -14.77078 47.15220  1.000 45.82862  ? 228 HOH D O   1 
HETATM 7588 O  O   . HOH H 3 .   ? 0.52776   -25.14926 35.73269  1.000 24.86988  ? 229 HOH D O   1 
HETATM 7589 O  O   . HOH H 3 .   ? 19.090    -29.408   28.747    1.000 36.69313  ? 230 HOH D O   1 
HETATM 7590 O  O   . HOH H 3 .   ? -11.10903 -33.04513 24.26319  1.000 34.75187  ? 231 HOH D O   1 
HETATM 7591 O  O   . HOH H 3 .   ? -12.46068 -26.89813 39.08988  1.000 48.17228  ? 232 HOH D O   1 
HETATM 7592 O  O   . HOH H 3 .   ? 26.98660  -24.05911 41.62258  1.000 39.00465  ? 233 HOH D O   1 
HETATM 7593 O  O   . HOH H 3 .   ? -2.84661  -41.97562 44.61156  1.000 41.33043  ? 234 HOH D O   1 
HETATM 7594 O  O   . HOH H 3 .   ? 6.77549   -25.29491 33.77671  1.000 29.23243  ? 235 HOH D O   1 
HETATM 7595 O  O   . HOH H 3 .   ? 10.71286  -18.77995 53.17074  1.000 34.06016  ? 236 HOH D O   1 
HETATM 7596 O  O   . HOH H 3 .   ? -2.20681  -11.14269 30.14526  1.000 30.14758  ? 237 HOH D O   1 
HETATM 7597 O  O   . HOH H 3 .   ? 2.38699   -28.30335 37.26456  1.000 34.57267  ? 238 HOH D O   1 
HETATM 7598 O  O   . HOH H 3 .   ? 5.33970   -44.10311 33.91212  1.000 43.17688  ? 239 HOH D O   1 
HETATM 7599 O  O   . HOH H 3 .   ? 12.20892  -32.32632 48.88779  1.000 34.21017  ? 240 HOH D O   1 
HETATM 7600 O  O   . HOH H 3 .   ? 8.61055   -33.06031 30.29826  1.000 32.06438  ? 241 HOH D O   1 
HETATM 7601 O  O   . HOH H 3 .   ? 9.16649   -32.57579 27.66656  1.000 40.27597  ? 242 HOH D O   1 
HETATM 7602 O  O   . HOH H 3 .   ? 4.45918   -39.64974 52.00840  1.000 39.87069  ? 243 HOH D O   1 
HETATM 7603 O  O   . HOH H 3 .   ? -2.01683  -14.40084 28.23561  1.000 36.75060  ? 244 HOH D O   1 
HETATM 7604 O  O   . HOH H 3 .   ? 1.44651   -39.14450 51.66529  1.000 52.84236  ? 245 HOH D O   1 
HETATM 7605 O  O   . HOH H 3 .   ? 4.37987   -17.48535 53.82061  1.000 38.90854  ? 246 HOH D O   1 
HETATM 7606 O  O   . HOH I 3 .   ? -1.72071  12.53138  27.08671  1.000 35.66082  ? 201 HOH A O   1 
HETATM 7607 O  O   . HOH I 3 .   ? -0.92122  11.49837  18.44274  1.000 38.00857  ? 202 HOH A O   1 
HETATM 7608 O  O   . HOH I 3 .   ? -3.94549  7.76475   23.76985  1.000 28.18067  ? 203 HOH A O   1 
HETATM 7609 O  O   . HOH I 3 .   ? -4.98704  -9.20064  30.13134  1.000 33.44989  ? 204 HOH A O   1 
HETATM 7610 O  O   . HOH I 3 .   ? 3.58441   4.63804   17.45805  1.000 43.32791  ? 205 HOH A O   1 
HETATM 7611 O  O   . HOH I 3 .   ? -5.93600  4.32964   29.81295  1.000 40.79852  ? 206 HOH A O   1 
HETATM 7612 O  O   . HOH I 3 .   ? -25.32907 -2.72611  26.22655  1.000 42.75312  ? 207 HOH A O   1 
HETATM 7613 O  O   . HOH I 3 .   ? -2.95413  4.35192   27.89271  1.000 31.04494  ? 208 HOH A O   1 
HETATM 7614 O  O   . HOH I 3 .   ? -29.76142 5.74737   13.58214  1.000 45.27219  ? 209 HOH A O   1 
HETATM 7615 O  O   . HOH I 3 .   ? 8.81525   1.01079   32.27979  1.000 40.84797  ? 210 HOH A O   1 
HETATM 7616 O  O   . HOH I 3 .   ? -11.31285 12.22839  37.61453  1.000 34.87798  ? 211 HOH A O   1 
HETATM 7617 O  O   . HOH I 3 .   ? -11.38749 9.75088   25.86305  1.000 24.44012  ? 212 HOH A O   1 
HETATM 7618 O  O   . HOH I 3 .   ? -3.77642  -7.01462  35.87834  1.000 28.66141  ? 213 HOH A O   1 
HETATM 7619 O  O   . HOH I 3 .   ? 1.67076   2.89437   46.89219  1.000 44.49759  ? 214 HOH A O   1 
HETATM 7620 O  O   . HOH I 3 .   ? 2.19631   -3.93784  33.33220  1.000 33.60658  ? 215 HOH A O   1 
HETATM 7621 O  O   . HOH I 3 .   ? -10.21639 17.47675  36.29488  1.000 31.57244  ? 216 HOH A O   1 
HETATM 7622 O  O   . HOH I 3 .   ? -20.17514 19.01898  19.67452  1.000 50.69181  ? 217 HOH A O   1 
HETATM 7623 O  O   . HOH I 3 .   ? -3.59739  11.74042  37.05467  1.000 44.58422  ? 218 HOH A O   1 
HETATM 7624 O  O   . HOH I 3 .   ? -5.69788  -11.06039 26.73913  1.000 34.72862  ? 219 HOH A O   1 
HETATM 7625 O  O   . HOH I 3 .   ? -15.35545 -3.07845  38.13194  1.000 45.94744  ? 220 HOH A O   1 
HETATM 7626 O  O   . HOH I 3 .   ? -20.53641 3.38948   41.15173  1.000 37.91277  ? 221 HOH A O   1 
HETATM 7627 O  O   . HOH I 3 .   ? -10.96759 14.66320  19.22648  1.000 30.66862  ? 222 HOH A O   1 
HETATM 7628 O  O   . HOH I 3 .   ? -13.71002 2.58674   12.35369  1.000 53.49634  ? 223 HOH A O   1 
HETATM 7629 O  O   . HOH I 3 .   ? 5.227     -1.079    42.040    1.000 41.22076  ? 224 HOH A O   1 
HETATM 7630 O  O   . HOH I 3 .   ? -9.60241  23.48016  23.33265  1.000 52.90727  ? 225 HOH A O   1 
HETATM 7631 O  O   . HOH I 3 .   ? 7.11726   6.26143   27.08367  1.000 46.46461  ? 226 HOH A O   1 
HETATM 7632 O  O   . HOH I 3 .   ? -21.20904 6.24151   13.55127  1.000 35.16039  ? 227 HOH A O   1 
HETATM 7633 O  O   . HOH I 3 .   ? -7.38605  9.13224   16.66455  1.000 39.59004  ? 228 HOH A O   1 
HETATM 7634 O  O   . HOH I 3 .   ? -18.77109 -3.85810  28.02797  1.000 31.68038  ? 229 HOH A O   1 
HETATM 7635 O  O   . HOH I 3 .   ? -6.02159  6.93488   30.63718  1.000 29.46560  ? 230 HOH A O   1 
HETATM 7636 O  O   . HOH I 3 .   ? -9.81745  12.79606  26.19557  1.000 31.52696  ? 231 HOH A O   1 
HETATM 7637 O  O   . HOH I 3 .   ? -16.80850 12.83021  13.14761  1.000 37.17739  ? 232 HOH A O   1 
HETATM 7638 O  O   . HOH I 3 .   ? -15.18141 8.35987   15.40043  1.000 37.56603  ? 233 HOH A O   1 
HETATM 7639 O  O   . HOH I 3 .   ? 0.67515   -11.87830 31.06697  1.000 35.59502  ? 234 HOH A O   1 
HETATM 7640 O  O   . HOH I 3 .   ? -7.23819  1.10155   29.55228  1.000 35.29615  ? 235 HOH A O   1 
HETATM 7641 O  O   . HOH I 3 .   ? -11.49679 6.15319   38.97407  1.000 33.09022  ? 236 HOH A O   1 
HETATM 7642 O  O   . HOH I 3 .   ? -8.40885  3.57108   29.41108  1.000 35.34731  ? 237 HOH A O   1 
HETATM 7643 O  O   . HOH I 3 .   ? -12.31226 10.11079  44.51880  1.000 45.58603  ? 238 HOH A O   1 
HETATM 7644 O  O   . HOH I 3 .   ? -5.25580  12.95460  32.39018  1.000 33.89883  ? 239 HOH A O   1 
HETATM 7645 O  O   . HOH I 3 .   ? -19.06312 6.35025   12.05079  1.000 50.82668  ? 240 HOH A O   1 
HETATM 7646 O  O   . HOH I 3 .   ? -0.04456  3.70065   39.48720  1.000 33.70726  ? 241 HOH A O   1 
HETATM 7647 O  O   . HOH I 3 .   ? 10.22160  3.50262   25.50906  1.000 41.93292  ? 242 HOH A O   1 
HETATM 7648 O  O   . HOH I 3 .   ? -3.90826  -12.72718 28.43066  1.000 39.68092  ? 243 HOH A O   1 
HETATM 7649 O  O   . HOH I 3 .   ? -1.739    19.489    37.721    1.000 42.27744  ? 244 HOH A O   1 
HETATM 7650 O  O   . HOH I 3 .   ? -11.87095 -7.68131  18.70666  1.000 33.21062  ? 245 HOH A O   1 
HETATM 7651 O  O   . HOH I 3 .   ? 8.31255   5.35308   25.09627  1.000 45.08285  ? 246 HOH A O   1 
HETATM 7652 O  O   . HOH I 3 .   ? -4.58327  11.11439  33.96467  1.000 36.79084  ? 247 HOH A O   1 
HETATM 7653 O  O   . HOH I 3 .   ? -2.91904  6.51049   29.59289  1.000 35.17039  ? 248 HOH A O   1 
HETATM 7654 O  O   . HOH I 3 .   ? -3.62535  8.40995   38.07170  1.000 36.27273  ? 249 HOH A O   1 
HETATM 7655 O  O   . HOH I 3 .   ? -17.31376 -4.85348  30.32381  1.000 46.27011  ? 250 HOH A O   1 
HETATM 7656 O  O   . HOH I 3 .   ? -1.70772  5.48215   38.12277  1.000 31.70127  ? 251 HOH A O   1 
HETATM 7657 O  O   . HOH I 3 .   ? -3.75250  9.29460   35.83742  1.000 33.90749  ? 252 HOH A O   1 
HETATM 7658 O  O   . HOH J 3 .   ? -22.58813 -10.20397 30.86883  1.000 46.65668  ? 301 HOH B O   1 
HETATM 7659 O  O   . HOH J 3 .   ? -31.51862 -20.25870 20.84813  1.000 32.51326  ? 302 HOH B O   1 
HETATM 7660 O  O   . HOH J 3 .   ? -24.69620 -6.98051  12.00742  1.000 36.19520  ? 303 HOH B O   1 
HETATM 7661 O  O   . HOH J 3 .   ? -12.70306 -26.83904 29.84708  1.000 29.84448  ? 304 HOH B O   1 
HETATM 7662 O  O   . HOH J 3 .   ? -12.36552 -12.56280 33.64512  1.000 52.65577  ? 305 HOH B O   1 
HETATM 7663 O  O   . HOH J 3 .   ? -17.90823 -31.68875 27.29517  1.000 35.53095  ? 306 HOH B O   1 
HETATM 7664 O  O   . HOH J 3 .   ? -18.45586 -15.10929 3.52362   1.000 39.52849  ? 307 HOH B O   1 
HETATM 7665 O  O   . HOH J 3 .   ? -15.42856 -24.35529 4.46005   1.000 36.67756  ? 308 HOH B O   1 
HETATM 7666 O  O   . HOH J 3 .   ? -25.25724 -20.55999 11.99782  1.000 37.96594  ? 309 HOH B O   1 
HETATM 7667 O  O   . HOH J 3 .   ? -25.31813 -11.13487 -2.68259  1.000 55.86360  ? 310 HOH B O   1 
HETATM 7668 O  O   . HOH J 3 .   ? -21.08095 -24.77147 12.79023  1.000 32.76739  ? 311 HOH B O   1 
HETATM 7669 O  O   . HOH J 3 .   ? -27.41440 -22.62192 15.68333  1.000 33.18902  ? 312 HOH B O   1 
HETATM 7670 O  O   . HOH J 3 .   ? -35.06121 -26.23355 24.62850  1.000 28.47622  ? 313 HOH B O   1 
HETATM 7671 O  O   . HOH J 3 .   ? -30.90548 -8.37918  12.20024  1.000 42.18663  ? 314 HOH B O   1 
HETATM 7672 O  O   . HOH J 3 .   ? -16.54827 -31.52599 19.80550  1.000 30.29223  ? 315 HOH B O   1 
HETATM 7673 O  O   . HOH J 3 .   ? -34.30454 -26.31876 22.01609  1.000 39.73129  ? 316 HOH B O   1 
HETATM 7674 O  O   . HOH J 3 .   ? -18.67815 -31.42266 11.95392  1.000 46.82138  ? 317 HOH B O   1 
HETATM 7675 O  O   . HOH J 3 .   ? -29.60021 -12.07452 6.04630   1.000 39.87271  ? 318 HOH B O   1 
HETATM 7676 O  O   . HOH J 3 .   ? -36.02486 -18.97483 19.95126  1.000 44.26533  ? 319 HOH B O   1 
HETATM 7677 O  O   . HOH J 3 .   ? -35.62849 -30.45622 20.35400  1.000 44.53914  ? 320 HOH B O   1 
HETATM 7678 O  O   . HOH J 3 .   ? -8.45672  -22.65344 27.97730  1.000 31.80870  ? 321 HOH B O   1 
HETATM 7679 O  O   . HOH J 3 .   ? -22.56599 -25.88103 20.62895  1.000 23.88109  ? 322 HOH B O   1 
HETATM 7680 O  O   . HOH J 3 .   ? -26.41648 -3.25890  17.75091  1.000 48.54257  ? 323 HOH B O   1 
HETATM 7681 O  O   . HOH J 3 .   ? -34.36680 -32.20114 21.78911  1.000 34.29348  ? 324 HOH B O   1 
HETATM 7682 O  O   . HOH J 3 .   ? -27.04780 -22.70035 34.37040  1.000 38.76381  ? 325 HOH B O   1 
HETATM 7683 O  O   . HOH J 3 .   ? -13.43982 -9.49428  17.82304  1.000 39.98992  ? 326 HOH B O   1 
HETATM 7684 O  O   . HOH J 3 .   ? -22.30188 -39.38066 14.51024  1.000 44.13411  ? 327 HOH B O   1 
HETATM 7685 O  O   . HOH J 3 .   ? -13.20795 -26.83569 14.66281  1.000 40.46338  ? 328 HOH B O   1 
HETATM 7686 O  O   . HOH J 3 .   ? -22.15938 -17.69285 -0.61511  1.000 49.28318  ? 329 HOH B O   1 
HETATM 7687 O  O   . HOH J 3 .   ? -27.24331 -27.76014 5.24782   1.000 45.46366  ? 330 HOH B O   1 
HETATM 7688 O  O   . HOH J 3 .   ? -9.25657  -12.12628 12.78234  1.000 51.51401  ? 331 HOH B O   1 
HETATM 7689 O  O   . HOH J 3 .   ? -9.58312  -11.35461 15.27287  1.000 48.71079  ? 332 HOH B O   1 
HETATM 7690 O  O   . HOH J 3 .   ? -28.30264 -4.70067  16.75278  1.000 44.72671  ? 333 HOH B O   1 
HETATM 7691 O  O   . HOH J 3 .   ? -28.27552 -29.14246 2.96958   1.000 56.10792  ? 334 HOH B O   1 
HETATM 7692 O  O   . HOH K 3 .   ? -38.22647 0.89035   38.71797  1.000 38.91265  ? 201 HOH C O   1 
HETATM 7693 O  O   . HOH K 3 .   ? -31.49926 24.65136  54.55356  1.000 52.90165  ? 202 HOH C O   1 
HETATM 7694 O  O   . HOH K 3 .   ? -33.22623 14.32083  28.34130  1.000 56.90777  ? 203 HOH C O   1 
HETATM 7695 O  O   . HOH K 3 .   ? -35.38919 6.81728   53.31860  1.000 32.23482  ? 204 HOH C O   1 
HETATM 7696 O  O   . HOH K 3 .   ? -44.02539 5.45906   36.37297  1.000 28.32037  ? 205 HOH C O   1 
HETATM 7697 O  O   . HOH K 3 .   ? -43.69346 9.97242   28.83416  1.000 44.98073  ? 206 HOH C O   1 
HETATM 7698 O  O   . HOH K 3 .   ? -16.33143 8.83305   43.67589  1.000 35.79700  ? 207 HOH C O   1 
HETATM 7699 O  O   . HOH K 3 .   ? -34.28762 6.46762   45.62179  1.000 26.22477  ? 208 HOH C O   1 
HETATM 7700 O  O   . HOH K 3 .   ? -32.43854 4.54918   51.73544  1.000 44.45754  ? 209 HOH C O   1 
HETATM 7701 O  O   . HOH K 3 .   ? -31.49743 10.72144  54.25123  1.000 40.66593  ? 210 HOH C O   1 
HETATM 7702 O  O   . HOH K 3 .   ? -18.91895 16.56558  50.78238  1.000 56.60278  ? 211 HOH C O   1 
HETATM 7703 O  O   . HOH K 3 .   ? -37.28635 20.60394  33.75078  1.000 49.59548  ? 212 HOH C O   1 
HETATM 7704 O  O   . HOH K 3 .   ? -21.59353 6.28009   41.80911  1.000 34.19352  ? 213 HOH C O   1 
HETATM 7705 O  O   . HOH K 3 .   ? -35.08073 20.92260  39.99651  1.000 32.49575  ? 214 HOH C O   1 
HETATM 7706 O  O   . HOH K 3 .   ? -28.04605 10.64033  43.79165  1.000 35.85298  ? 215 HOH C O   1 
HETATM 7707 O  O   . HOH K 3 .   ? -32.68800 6.91787   32.57617  1.000 46.80059  ? 216 HOH C O   1 
HETATM 7708 O  O   . HOH K 3 .   ? -22.52801 12.29872  44.70668  1.000 32.45409  ? 217 HOH C O   1 
HETATM 7709 O  O   . HOH K 3 .   ? -39.90122 0.13394   46.05175  1.000 37.19810  ? 218 HOH C O   1 
HETATM 7710 O  O   . HOH K 3 .   ? -31.39514 12.22372  49.21441  1.000 35.23803  ? 219 HOH C O   1 
HETATM 7711 O  O   . HOH K 3 .   ? -42.97881 4.76956   50.88244  1.000 38.57997  ? 220 HOH C O   1 
HETATM 7712 O  O   . HOH K 3 .   ? -32.83866 10.54029  63.82758  1.000 51.88828  ? 221 HOH C O   1 
HETATM 7713 O  O   . HOH K 3 .   ? -14.29673 10.48433  42.80467  1.000 34.89248  ? 222 HOH C O   1 
HETATM 7714 O  O   . HOH K 3 .   ? -45.06224 5.16457   53.03343  1.000 38.97388  ? 223 HOH C O   1 
HETATM 7715 O  O   . HOH L 3 .   ? -22.69681 -21.25885 74.70442  1.000 48.01053  ? 201 HOH E O   1 
HETATM 7716 O  O   . HOH L 3 .   ? -21.96629 -20.99189 43.23445  1.000 41.07168  ? 202 HOH E O   1 
HETATM 7717 O  O   . HOH L 3 .   ? -34.15354 -25.39837 66.40177  1.000 57.23151  ? 203 HOH E O   1 
HETATM 7718 O  O   . HOH L 3 .   ? -11.87990 -27.96932 55.40667  1.000 41.19608  ? 204 HOH E O   1 
HETATM 7719 O  O   . HOH L 3 .   ? -24.10744 -17.30522 57.09515  1.000 40.47891  ? 205 HOH E O   1 
HETATM 7720 O  O   . HOH L 3 .   ? -16.51110 -16.57195 56.00713  1.000 27.98937  ? 206 HOH E O   1 
HETATM 7721 O  O   . HOH L 3 .   ? -27.61270 -13.74208 74.14364  1.000 48.06513  ? 207 HOH E O   1 
HETATM 7722 O  O   . HOH L 3 .   ? -27.08870 -11.33811 74.06668  1.000 44.50040  ? 208 HOH E O   1 
HETATM 7723 O  O   . HOH L 3 .   ? -11.26404 -5.55743  64.40041  1.000 47.26738  ? 209 HOH E O   1 
HETATM 7724 O  O   . HOH L 3 .   ? -8.60106  -16.11884 67.14597  1.000 44.37145  ? 210 HOH E O   1 
HETATM 7725 O  O   . HOH L 3 .   ? -18.74265 -11.37361 50.31332  1.000 39.03650  ? 211 HOH E O   1 
HETATM 7726 O  O   . HOH L 3 .   ? -24.303   -24.116   50.893    1.000 31.30744  ? 212 HOH E O   1 
HETATM 7727 O  O   . HOH L 3 .   ? -19.60972 -22.84061 59.04125  1.000 38.02220  ? 213 HOH E O   1 
HETATM 7728 O  O   . HOH L 3 .   ? -22.22868 -20.53449 54.48993  1.000 31.43351  ? 214 HOH E O   1 
HETATM 7729 O  O   . HOH L 3 .   ? -12.19044 -27.83546 49.33357  1.000 39.31288  ? 215 HOH E O   1 
HETATM 7730 O  O   . HOH L 3 .   ? -27.42717 -12.04145 53.29922  1.000 56.26178  ? 216 HOH E O   1 
HETATM 7731 O  O   . HOH L 3 .   ? -24.53779 -9.35976  54.96675  1.000 52.89234  ? 217 HOH E O   1 
HETATM 7732 O  O   . HOH L 3 .   ? -11.33831 -24.25104 68.26480  1.000 58.00325  ? 218 HOH E O   1 
HETATM 7733 O  O   . HOH L 3 .   ? -14.08753 -29.35247 47.32772  1.000 36.23968  ? 219 HOH E O   1 
HETATM 7734 O  O   . HOH L 3 .   ? -19.48291 -20.82774 62.04932  1.000 41.29373  ? 220 HOH E O   1 
HETATM 7735 O  O   . HOH L 3 .   ? -19.46874 -21.05049 64.69388  1.000 57.20941  ? 221 HOH E O   1 
HETATM 7736 O  O   . HOH M 3 .   ? 7.42718   1.81353   83.91841  1.000 57.77115  ? 201 HOH F O   1 
HETATM 7737 O  O   . HOH M 3 .   ? -14.31641 9.17656   81.35121  1.000 57.18592  ? 202 HOH F O   1 
HETATM 7738 O  O   . HOH M 3 .   ? -10.60314 0.29350   90.55138  1.000 42.09632  ? 203 HOH F O   1 
HETATM 7739 O  O   . HOH M 3 .   ? -23.44519 -3.79651  89.01689  1.000 48.99065  ? 204 HOH F O   1 
HETATM 7740 O  O   . HOH M 3 .   ? -8.87339  -7.53709  91.62644  1.000 47.17208  ? 205 HOH F O   1 
HETATM 7741 O  O   . HOH M 3 .   ? -15.79767 2.45193   95.48934  1.000 45.02334  ? 206 HOH F O   1 
HETATM 7742 O  O   . HOH M 3 .   ? -4.56223  -17.48424 95.47966  1.000 48.69199  ? 207 HOH F O   1 
HETATM 7743 O  O   . HOH M 3 .   ? -2.92024  -17.63928 93.33232  1.000 50.66976  ? 208 HOH F O   1 
# 
