data_8ZMI
# 
_entry.id   8ZMI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZMI         pdb_00008zmi 10.2210/pdb8zmi/pdb 
WWPDB D_1300048110 ?            ?                   
EMDB  EMD-60248    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'EM metadata'     1 0 2025-03-12 ? 
3 'Additional map'  1 0 2025-03-12 1 
4 'Half map'        1 0 2025-03-12 1 
5 'Half map'        1 0 2025-03-12 2 
6 Image             1 0 2025-03-12 ? 
7 'Primary map'     1 0 2025-03-12 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZMI 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of BMV TLS-TyrRS-ATP(Pre-1a state)' 
_pdbx_database_related.db_id          EMD-60248 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              kmzhang@ustc.edu.cn 
_pdbx_contact_author.name_first         Kaiming 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0414-4776 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, K.' 1 0000-0003-0414-4776 
'Li, S.'    2 0000-0002-7041-5960 
'Yang, W.'  3 0009-0005-9328-2792 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                1276 
_citation.page_last                 1276 
_citation.title                     'Structural insights into dynamics of the BMV TLS aminoacylation.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-56612-4 
_citation.pdbx_database_id_PubMed   39900568 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, W.'  1 ?                   
primary 'Yi, R.'    2 ?                   
primary 'Yao, J.'   3 ?                   
primary 'Gao, Y.'   4 ?                   
primary 'Li, S.'    5 0000-0002-7041-5960 
primary 'Gong, Q.'  6 0000-0002-3034-6008 
primary 'Zhang, K.' 7 0000-0003-0414-4776 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'tyrosine--tRNA ligase'     43179.648 2 6.1.1.1 ? ? ? 
2 polymer     man 'RNA (169-MER)'             54354.141 1 ?       ? ? ? 
3 non-polymer syn "ADENOSINE-5'-TRIPHOSPHATE" 507.181   1 ?       ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Tyrosyl-tRNA synthetase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'   no no 
;MEQAPSEALQSLSVSDSQIPQSSNSTPQLSPEEKFKIVRSVGEECIQEDELLNLLTKKPEPVCYDGFEPSGRMHIAQGVM
KTISVNKLTSAGCRVKIWIADWFAKLNNKMGGDLKKIETVGRYLIEIWKAVGMDVEGGKVEFLWSSKEINARADEYWPLV
LDIAQKNNLKRIIRCSQIMGRSEQDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCDDIKRKNKPIILS
HHMLPGLQQGQEKMSKSDPSSSVFMEDEEAEVNVKIKKAYCPPKVVEGNPCLEYIKYLILPWFNEFTVERSADNGGNKTF
KSYEELIADYESGELHPADLKPALSKSLNKILEPVREHFRKDSNAKELLKRVKAYRVTK
;
;MEQAPSEALQSLSVSDSQIPQSSNSTPQLSPEEKFKIVRSVGEECIQEDELLNLLTKKPEPVCYDGFEPSGRMHIAQGVM
KTISVNKLTSAGCRVKIWIADWFAKLNNKMGGDLKKIETVGRYLIEIWKAVGMDVEGGKVEFLWSSKEINARADEYWPLV
LDIAQKNNLKRIIRCSQIMGRSEQDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCDDIKRKNKPIILS
HHMLPGLQQGQEKMSKSDPSSSVFMEDEEAEVNVKIKKAYCPPKVVEGNPCLEYIKYLILPWFNEFTVERSADNGGNKTF
KSYEELIADYESGELHPADLKPALSKSLNKILEPVREHFRKDSNAKELLKRVKAYRVTK
;
A,B ? 
2 polyribonucleotide no no 
;CGUGGUUGACACGCAGACCUCUUACAAGAGUGUCUAGGUGCCUUUGAGAGUUACUCUUUGCUCUCUUCGGAAGAACCCUU
AGGGGUUCGUGCAUGGGCUUGCAUAGCAAGUCUUAGAAUGCGGGUACCGUACAGUGUUGAAAAACACUGUAAAUCUCUAA
AAGAGACCA
;
;CGUGGUUGACACGCAGACCUCUUACAAGAGUGUCUAGGUGCCUUUGAGAGUUACUCUUUGCUCUCUUCGGAAGAACCCUU
AGGGGUUCGUGCAUGGGCUUGCAUAGCAAGUCUUAGAAUGCGGGUACCGUACAGUGUUGAAAAACACUGUAAAUCUCUAA
AAGAGACCA
;
C   ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        "ADENOSINE-5'-TRIPHOSPHATE" 
_pdbx_entity_nonpoly.comp_id     ATP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   GLN n 
1 4   ALA n 
1 5   PRO n 
1 6   SER n 
1 7   GLU n 
1 8   ALA n 
1 9   LEU n 
1 10  GLN n 
1 11  SER n 
1 12  LEU n 
1 13  SER n 
1 14  VAL n 
1 15  SER n 
1 16  ASP n 
1 17  SER n 
1 18  GLN n 
1 19  ILE n 
1 20  PRO n 
1 21  GLN n 
1 22  SER n 
1 23  SER n 
1 24  ASN n 
1 25  SER n 
1 26  THR n 
1 27  PRO n 
1 28  GLN n 
1 29  LEU n 
1 30  SER n 
1 31  PRO n 
1 32  GLU n 
1 33  GLU n 
1 34  LYS n 
1 35  PHE n 
1 36  LYS n 
1 37  ILE n 
1 38  VAL n 
1 39  ARG n 
1 40  SER n 
1 41  VAL n 
1 42  GLY n 
1 43  GLU n 
1 44  GLU n 
1 45  CYS n 
1 46  ILE n 
1 47  GLN n 
1 48  GLU n 
1 49  ASP n 
1 50  GLU n 
1 51  LEU n 
1 52  LEU n 
1 53  ASN n 
1 54  LEU n 
1 55  LEU n 
1 56  THR n 
1 57  LYS n 
1 58  LYS n 
1 59  PRO n 
1 60  GLU n 
1 61  PRO n 
1 62  VAL n 
1 63  CYS n 
1 64  TYR n 
1 65  ASP n 
1 66  GLY n 
1 67  PHE n 
1 68  GLU n 
1 69  PRO n 
1 70  SER n 
1 71  GLY n 
1 72  ARG n 
1 73  MET n 
1 74  HIS n 
1 75  ILE n 
1 76  ALA n 
1 77  GLN n 
1 78  GLY n 
1 79  VAL n 
1 80  MET n 
1 81  LYS n 
1 82  THR n 
1 83  ILE n 
1 84  SER n 
1 85  VAL n 
1 86  ASN n 
1 87  LYS n 
1 88  LEU n 
1 89  THR n 
1 90  SER n 
1 91  ALA n 
1 92  GLY n 
1 93  CYS n 
1 94  ARG n 
1 95  VAL n 
1 96  LYS n 
1 97  ILE n 
1 98  TRP n 
1 99  ILE n 
1 100 ALA n 
1 101 ASP n 
1 102 TRP n 
1 103 PHE n 
1 104 ALA n 
1 105 LYS n 
1 106 LEU n 
1 107 ASN n 
1 108 ASN n 
1 109 LYS n 
1 110 MET n 
1 111 GLY n 
1 112 GLY n 
1 113 ASP n 
1 114 LEU n 
1 115 LYS n 
1 116 LYS n 
1 117 ILE n 
1 118 GLU n 
1 119 THR n 
1 120 VAL n 
1 121 GLY n 
1 122 ARG n 
1 123 TYR n 
1 124 LEU n 
1 125 ILE n 
1 126 GLU n 
1 127 ILE n 
1 128 TRP n 
1 129 LYS n 
1 130 ALA n 
1 131 VAL n 
1 132 GLY n 
1 133 MET n 
1 134 ASP n 
1 135 VAL n 
1 136 GLU n 
1 137 GLY n 
1 138 GLY n 
1 139 LYS n 
1 140 VAL n 
1 141 GLU n 
1 142 PHE n 
1 143 LEU n 
1 144 TRP n 
1 145 SER n 
1 146 SER n 
1 147 LYS n 
1 148 GLU n 
1 149 ILE n 
1 150 ASN n 
1 151 ALA n 
1 152 ARG n 
1 153 ALA n 
1 154 ASP n 
1 155 GLU n 
1 156 TYR n 
1 157 TRP n 
1 158 PRO n 
1 159 LEU n 
1 160 VAL n 
1 161 LEU n 
1 162 ASP n 
1 163 ILE n 
1 164 ALA n 
1 165 GLN n 
1 166 LYS n 
1 167 ASN n 
1 168 ASN n 
1 169 LEU n 
1 170 LYS n 
1 171 ARG n 
1 172 ILE n 
1 173 ILE n 
1 174 ARG n 
1 175 CYS n 
1 176 SER n 
1 177 GLN n 
1 178 ILE n 
1 179 MET n 
1 180 GLY n 
1 181 ARG n 
1 182 SER n 
1 183 GLU n 
1 184 GLN n 
1 185 ASP n 
1 186 GLU n 
1 187 LEU n 
1 188 THR n 
1 189 ALA n 
1 190 ALA n 
1 191 GLN n 
1 192 ILE n 
1 193 PHE n 
1 194 TYR n 
1 195 PRO n 
1 196 CYS n 
1 197 MET n 
1 198 GLN n 
1 199 CYS n 
1 200 ALA n 
1 201 ASP n 
1 202 ILE n 
1 203 PHE n 
1 204 PHE n 
1 205 LEU n 
1 206 LYS n 
1 207 ALA n 
1 208 ASP n 
1 209 ILE n 
1 210 CYS n 
1 211 GLN n 
1 212 LEU n 
1 213 GLY n 
1 214 MET n 
1 215 ASP n 
1 216 GLN n 
1 217 ARG n 
1 218 LYS n 
1 219 VAL n 
1 220 ASN n 
1 221 VAL n 
1 222 LEU n 
1 223 ALA n 
1 224 ARG n 
1 225 GLU n 
1 226 TYR n 
1 227 CYS n 
1 228 ASP n 
1 229 ASP n 
1 230 ILE n 
1 231 LYS n 
1 232 ARG n 
1 233 LYS n 
1 234 ASN n 
1 235 LYS n 
1 236 PRO n 
1 237 ILE n 
1 238 ILE n 
1 239 LEU n 
1 240 SER n 
1 241 HIS n 
1 242 HIS n 
1 243 MET n 
1 244 LEU n 
1 245 PRO n 
1 246 GLY n 
1 247 LEU n 
1 248 GLN n 
1 249 GLN n 
1 250 GLY n 
1 251 GLN n 
1 252 GLU n 
1 253 LYS n 
1 254 MET n 
1 255 SER n 
1 256 LYS n 
1 257 SER n 
1 258 ASP n 
1 259 PRO n 
1 260 SER n 
1 261 SER n 
1 262 SER n 
1 263 VAL n 
1 264 PHE n 
1 265 MET n 
1 266 GLU n 
1 267 ASP n 
1 268 GLU n 
1 269 GLU n 
1 270 ALA n 
1 271 GLU n 
1 272 VAL n 
1 273 ASN n 
1 274 VAL n 
1 275 LYS n 
1 276 ILE n 
1 277 LYS n 
1 278 LYS n 
1 279 ALA n 
1 280 TYR n 
1 281 CYS n 
1 282 PRO n 
1 283 PRO n 
1 284 LYS n 
1 285 VAL n 
1 286 VAL n 
1 287 GLU n 
1 288 GLY n 
1 289 ASN n 
1 290 PRO n 
1 291 CYS n 
1 292 LEU n 
1 293 GLU n 
1 294 TYR n 
1 295 ILE n 
1 296 LYS n 
1 297 TYR n 
1 298 LEU n 
1 299 ILE n 
1 300 LEU n 
1 301 PRO n 
1 302 TRP n 
1 303 PHE n 
1 304 ASN n 
1 305 GLU n 
1 306 PHE n 
1 307 THR n 
1 308 VAL n 
1 309 GLU n 
1 310 ARG n 
1 311 SER n 
1 312 ALA n 
1 313 ASP n 
1 314 ASN n 
1 315 GLY n 
1 316 GLY n 
1 317 ASN n 
1 318 LYS n 
1 319 THR n 
1 320 PHE n 
1 321 LYS n 
1 322 SER n 
1 323 TYR n 
1 324 GLU n 
1 325 GLU n 
1 326 LEU n 
1 327 ILE n 
1 328 ALA n 
1 329 ASP n 
1 330 TYR n 
1 331 GLU n 
1 332 SER n 
1 333 GLY n 
1 334 GLU n 
1 335 LEU n 
1 336 HIS n 
1 337 PRO n 
1 338 ALA n 
1 339 ASP n 
1 340 LEU n 
1 341 LYS n 
1 342 PRO n 
1 343 ALA n 
1 344 LEU n 
1 345 SER n 
1 346 LYS n 
1 347 SER n 
1 348 LEU n 
1 349 ASN n 
1 350 LYS n 
1 351 ILE n 
1 352 LEU n 
1 353 GLU n 
1 354 PRO n 
1 355 VAL n 
1 356 ARG n 
1 357 GLU n 
1 358 HIS n 
1 359 PHE n 
1 360 ARG n 
1 361 LYS n 
1 362 ASP n 
1 363 SER n 
1 364 ASN n 
1 365 ALA n 
1 366 LYS n 
1 367 GLU n 
1 368 LEU n 
1 369 LEU n 
1 370 LYS n 
1 371 ARG n 
1 372 VAL n 
1 373 LYS n 
1 374 ALA n 
1 375 TYR n 
1 376 ARG n 
1 377 VAL n 
1 378 THR n 
1 379 LYS n 
2 1   C   n 
2 2   G   n 
2 3   U   n 
2 4   G   n 
2 5   G   n 
2 6   U   n 
2 7   U   n 
2 8   G   n 
2 9   A   n 
2 10  C   n 
2 11  A   n 
2 12  C   n 
2 13  G   n 
2 14  C   n 
2 15  A   n 
2 16  G   n 
2 17  A   n 
2 18  C   n 
2 19  C   n 
2 20  U   n 
2 21  C   n 
2 22  U   n 
2 23  U   n 
2 24  A   n 
2 25  C   n 
2 26  A   n 
2 27  A   n 
2 28  G   n 
2 29  A   n 
2 30  G   n 
2 31  U   n 
2 32  G   n 
2 33  U   n 
2 34  C   n 
2 35  U   n 
2 36  A   n 
2 37  G   n 
2 38  G   n 
2 39  U   n 
2 40  G   n 
2 41  C   n 
2 42  C   n 
2 43  U   n 
2 44  U   n 
2 45  U   n 
2 46  G   n 
2 47  A   n 
2 48  G   n 
2 49  A   n 
2 50  G   n 
2 51  U   n 
2 52  U   n 
2 53  A   n 
2 54  C   n 
2 55  U   n 
2 56  C   n 
2 57  U   n 
2 58  U   n 
2 59  U   n 
2 60  G   n 
2 61  C   n 
2 62  U   n 
2 63  C   n 
2 64  U   n 
2 65  C   n 
2 66  U   n 
2 67  U   n 
2 68  C   n 
2 69  G   n 
2 70  G   n 
2 71  A   n 
2 72  A   n 
2 73  G   n 
2 74  A   n 
2 75  A   n 
2 76  C   n 
2 77  C   n 
2 78  C   n 
2 79  U   n 
2 80  U   n 
2 81  A   n 
2 82  G   n 
2 83  G   n 
2 84  G   n 
2 85  G   n 
2 86  U   n 
2 87  U   n 
2 88  C   n 
2 89  G   n 
2 90  U   n 
2 91  G   n 
2 92  C   n 
2 93  A   n 
2 94  U   n 
2 95  G   n 
2 96  G   n 
2 97  G   n 
2 98  C   n 
2 99  U   n 
2 100 U   n 
2 101 G   n 
2 102 C   n 
2 103 A   n 
2 104 U   n 
2 105 A   n 
2 106 G   n 
2 107 C   n 
2 108 A   n 
2 109 A   n 
2 110 G   n 
2 111 U   n 
2 112 C   n 
2 113 U   n 
2 114 U   n 
2 115 A   n 
2 116 G   n 
2 117 A   n 
2 118 A   n 
2 119 U   n 
2 120 G   n 
2 121 C   n 
2 122 G   n 
2 123 G   n 
2 124 G   n 
2 125 U   n 
2 126 A   n 
2 127 C   n 
2 128 C   n 
2 129 G   n 
2 130 U   n 
2 131 A   n 
2 132 C   n 
2 133 A   n 
2 134 G   n 
2 135 U   n 
2 136 G   n 
2 137 U   n 
2 138 U   n 
2 139 G   n 
2 140 A   n 
2 141 A   n 
2 142 A   n 
2 143 A   n 
2 144 A   n 
2 145 C   n 
2 146 A   n 
2 147 C   n 
2 148 U   n 
2 149 G   n 
2 150 U   n 
2 151 A   n 
2 152 A   n 
2 153 A   n 
2 154 U   n 
2 155 C   n 
2 156 U   n 
2 157 C   n 
2 158 U   n 
2 159 A   n 
2 160 A   n 
2 161 A   n 
2 162 A   n 
2 163 G   n 
2 164 A   n 
2 165 G   n 
2 166 A   n 
2 167 C   n 
2 168 C   n 
2 169 A   n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 379 ? ? PHAVU_002G027700g ? ? ? ? ? ? 'Phaseolus vulgaris' 3885  ? ? ? ? ? ? ? ? 
'Escherichia coli'                               562    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 169 ? ? ?                 ? ? ? ? ? ? 'Brome mosaic virus' 12302 ? ? ? ? ? ? ? ? 
'in vitro transcription vector pT7-Fluc(deltai)' 905932 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P'   347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'        133.103 
ATP non-polymer         . "ADENOSINE-5'-TRIPHOSPHATE"  ? 'C10 H16 N5 O13 P3' 507.181 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'    323.197 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'      121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P'   363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'       181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'    324.181 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   PRO 5   5   ?   ?   ?   A . n 
A 1 6   SER 6   6   ?   ?   ?   A . n 
A 1 7   GLU 7   7   ?   ?   ?   A . n 
A 1 8   ALA 8   8   ?   ?   ?   A . n 
A 1 9   LEU 9   9   ?   ?   ?   A . n 
A 1 10  GLN 10  10  ?   ?   ?   A . n 
A 1 11  SER 11  11  ?   ?   ?   A . n 
A 1 12  LEU 12  12  ?   ?   ?   A . n 
A 1 13  SER 13  13  ?   ?   ?   A . n 
A 1 14  VAL 14  14  ?   ?   ?   A . n 
A 1 15  SER 15  15  ?   ?   ?   A . n 
A 1 16  ASP 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  GLN 18  18  ?   ?   ?   A . n 
A 1 19  ILE 19  19  ?   ?   ?   A . n 
A 1 20  PRO 20  20  ?   ?   ?   A . n 
A 1 21  GLN 21  21  ?   ?   ?   A . n 
A 1 22  SER 22  22  ?   ?   ?   A . n 
A 1 23  SER 23  23  ?   ?   ?   A . n 
A 1 24  ASN 24  24  ?   ?   ?   A . n 
A 1 25  SER 25  25  ?   ?   ?   A . n 
A 1 26  THR 26  26  ?   ?   ?   A . n 
A 1 27  PRO 27  27  ?   ?   ?   A . n 
A 1 28  GLN 28  28  ?   ?   ?   A . n 
A 1 29  LEU 29  29  ?   ?   ?   A . n 
A 1 30  SER 30  30  ?   ?   ?   A . n 
A 1 31  PRO 31  31  31  PRO PRO A . n 
A 1 32  GLU 32  32  32  GLU GLU A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  LYS 34  34  34  LYS LYS A . n 
A 1 35  PHE 35  35  35  PHE PHE A . n 
A 1 36  LYS 36  36  36  LYS LYS A . n 
A 1 37  ILE 37  37  37  ILE ILE A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  ARG 39  39  39  ARG ARG A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  CYS 45  45  45  CYS CYS A . n 
A 1 46  ILE 46  46  46  ILE ILE A . n 
A 1 47  GLN 47  47  47  GLN GLN A . n 
A 1 48  GLU 48  48  48  GLU GLU A . n 
A 1 49  ASP 49  49  49  ASP ASP A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  LEU 51  51  51  LEU LEU A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  LEU 54  54  54  LEU LEU A . n 
A 1 55  LEU 55  55  55  LEU LEU A . n 
A 1 56  THR 56  56  56  THR THR A . n 
A 1 57  LYS 57  57  57  LYS LYS A . n 
A 1 58  LYS 58  58  58  LYS LYS A . n 
A 1 59  PRO 59  59  59  PRO PRO A . n 
A 1 60  GLU 60  60  60  GLU GLU A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  VAL 62  62  62  VAL VAL A . n 
A 1 63  CYS 63  63  63  CYS CYS A . n 
A 1 64  TYR 64  64  64  TYR TYR A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  PHE 67  67  67  PHE PHE A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  PRO 69  69  69  PRO PRO A . n 
A 1 70  SER 70  70  70  SER SER A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  MET 73  73  73  MET MET A . n 
A 1 74  HIS 74  74  74  HIS HIS A . n 
A 1 75  ILE 75  75  75  ILE ILE A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  GLN 77  77  77  GLN GLN A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  VAL 79  79  79  VAL VAL A . n 
A 1 80  MET 80  80  80  MET MET A . n 
A 1 81  LYS 81  81  81  LYS LYS A . n 
A 1 82  THR 82  82  82  THR THR A . n 
A 1 83  ILE 83  83  83  ILE ILE A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  LYS 87  87  87  LYS LYS A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  THR 89  89  89  THR THR A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  ALA 91  91  91  ALA ALA A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  CYS 93  93  93  CYS CYS A . n 
A 1 94  ARG 94  94  94  ARG ARG A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  LYS 96  96  96  LYS LYS A . n 
A 1 97  ILE 97  97  97  ILE ILE A . n 
A 1 98  TRP 98  98  98  TRP TRP A . n 
A 1 99  ILE 99  99  99  ILE ILE A . n 
A 1 100 ALA 100 100 100 ALA ALA A . n 
A 1 101 ASP 101 101 101 ASP ASP A . n 
A 1 102 TRP 102 102 102 TRP TRP A . n 
A 1 103 PHE 103 103 103 PHE PHE A . n 
A 1 104 ALA 104 104 104 ALA ALA A . n 
A 1 105 LYS 105 105 105 LYS LYS A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 ASN 108 108 108 ASN ASN A . n 
A 1 109 LYS 109 109 109 LYS LYS A . n 
A 1 110 MET 110 110 110 MET MET A . n 
A 1 111 GLY 111 111 111 GLY GLY A . n 
A 1 112 GLY 112 112 112 GLY GLY A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 LEU 114 114 114 LEU LEU A . n 
A 1 115 LYS 115 115 115 LYS LYS A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 ILE 117 117 117 ILE ILE A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 THR 119 119 119 THR THR A . n 
A 1 120 VAL 120 120 120 VAL VAL A . n 
A 1 121 GLY 121 121 121 GLY GLY A . n 
A 1 122 ARG 122 122 122 ARG ARG A . n 
A 1 123 TYR 123 123 123 TYR TYR A . n 
A 1 124 LEU 124 124 124 LEU LEU A . n 
A 1 125 ILE 125 125 125 ILE ILE A . n 
A 1 126 GLU 126 126 126 GLU GLU A . n 
A 1 127 ILE 127 127 127 ILE ILE A . n 
A 1 128 TRP 128 128 128 TRP TRP A . n 
A 1 129 LYS 129 129 129 LYS LYS A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 GLY 132 132 132 GLY GLY A . n 
A 1 133 MET 133 133 133 MET MET A . n 
A 1 134 ASP 134 134 134 ASP ASP A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 LYS 139 139 139 LYS LYS A . n 
A 1 140 VAL 140 140 140 VAL VAL A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 TRP 144 144 144 TRP TRP A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 SER 146 146 146 SER SER A . n 
A 1 147 LYS 147 147 147 LYS LYS A . n 
A 1 148 GLU 148 148 148 GLU GLU A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 ASN 150 150 150 ASN ASN A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 ASP 154 154 154 ASP ASP A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 TYR 156 156 156 TYR TYR A . n 
A 1 157 TRP 157 157 157 TRP TRP A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 ASP 162 162 162 ASP ASP A . n 
A 1 163 ILE 163 163 163 ILE ILE A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 GLN 165 165 165 GLN GLN A . n 
A 1 166 LYS 166 166 166 LYS LYS A . n 
A 1 167 ASN 167 167 167 ASN ASN A . n 
A 1 168 ASN 168 168 168 ASN ASN A . n 
A 1 169 LEU 169 169 169 LEU LEU A . n 
A 1 170 LYS 170 170 170 LYS LYS A . n 
A 1 171 ARG 171 171 171 ARG ARG A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 ILE 173 173 173 ILE ILE A . n 
A 1 174 ARG 174 174 174 ARG ARG A . n 
A 1 175 CYS 175 175 175 CYS CYS A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 GLY 180 180 180 GLY GLY A . n 
A 1 181 ARG 181 181 181 ARG ARG A . n 
A 1 182 SER 182 182 182 SER SER A . n 
A 1 183 GLU 183 183 183 GLU GLU A . n 
A 1 184 GLN 184 184 184 GLN GLN A . n 
A 1 185 ASP 185 185 185 ASP ASP A . n 
A 1 186 GLU 186 186 186 GLU GLU A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 THR 188 188 188 THR THR A . n 
A 1 189 ALA 189 189 189 ALA ALA A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 GLN 191 191 191 GLN GLN A . n 
A 1 192 ILE 192 192 192 ILE ILE A . n 
A 1 193 PHE 193 193 193 PHE PHE A . n 
A 1 194 TYR 194 194 194 TYR TYR A . n 
A 1 195 PRO 195 195 195 PRO PRO A . n 
A 1 196 CYS 196 196 196 CYS CYS A . n 
A 1 197 MET 197 197 197 MET MET A . n 
A 1 198 GLN 198 198 198 GLN GLN A . n 
A 1 199 CYS 199 199 199 CYS CYS A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 ASP 201 201 201 ASP ASP A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 PHE 203 203 203 PHE PHE A . n 
A 1 204 PHE 204 204 204 PHE PHE A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 LYS 206 206 206 LYS LYS A . n 
A 1 207 ALA 207 207 207 ALA ALA A . n 
A 1 208 ASP 208 208 208 ASP ASP A . n 
A 1 209 ILE 209 209 209 ILE ILE A . n 
A 1 210 CYS 210 210 210 CYS CYS A . n 
A 1 211 GLN 211 211 211 GLN GLN A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 GLY 213 213 213 GLY GLY A . n 
A 1 214 MET 214 214 214 MET MET A . n 
A 1 215 ASP 215 215 215 ASP ASP A . n 
A 1 216 GLN 216 216 216 GLN GLN A . n 
A 1 217 ARG 217 217 217 ARG ARG A . n 
A 1 218 LYS 218 218 218 LYS LYS A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 ASN 220 220 220 ASN ASN A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 ALA 223 223 223 ALA ALA A . n 
A 1 224 ARG 224 224 224 ARG ARG A . n 
A 1 225 GLU 225 225 225 GLU GLU A . n 
A 1 226 TYR 226 226 226 TYR TYR A . n 
A 1 227 CYS 227 227 227 CYS CYS A . n 
A 1 228 ASP 228 228 228 ASP ASP A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 ILE 230 230 230 ILE ILE A . n 
A 1 231 LYS 231 231 231 LYS LYS A . n 
A 1 232 ARG 232 232 232 ARG ARG A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 ASN 234 234 234 ASN ASN A . n 
A 1 235 LYS 235 235 235 LYS LYS A . n 
A 1 236 PRO 236 236 236 PRO PRO A . n 
A 1 237 ILE 237 237 237 ILE ILE A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 SER 240 240 240 SER SER A . n 
A 1 241 HIS 241 241 241 HIS HIS A . n 
A 1 242 HIS 242 242 242 HIS HIS A . n 
A 1 243 MET 243 243 243 MET MET A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 PRO 245 245 245 PRO PRO A . n 
A 1 246 GLY 246 246 246 GLY GLY A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 GLN 248 248 248 GLN GLN A . n 
A 1 249 GLN 249 249 249 GLN GLN A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 GLN 251 251 251 GLN GLN A . n 
A 1 252 GLU 252 252 252 GLU GLU A . n 
A 1 253 LYS 253 253 253 LYS LYS A . n 
A 1 254 MET 254 254 254 MET MET A . n 
A 1 255 SER 255 255 255 SER SER A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 SER 257 257 257 SER SER A . n 
A 1 258 ASP 258 258 258 ASP ASP A . n 
A 1 259 PRO 259 259 259 PRO PRO A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 SER 262 262 262 SER SER A . n 
A 1 263 VAL 263 263 263 VAL VAL A . n 
A 1 264 PHE 264 264 264 PHE PHE A . n 
A 1 265 MET 265 265 265 MET MET A . n 
A 1 266 GLU 266 266 266 GLU GLU A . n 
A 1 267 ASP 267 267 267 ASP ASP A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 GLU 269 269 269 GLU GLU A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 GLU 271 271 271 GLU GLU A . n 
A 1 272 VAL 272 272 272 VAL VAL A . n 
A 1 273 ASN 273 273 273 ASN ASN A . n 
A 1 274 VAL 274 274 274 VAL VAL A . n 
A 1 275 LYS 275 275 275 LYS LYS A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 LYS 277 277 277 LYS LYS A . n 
A 1 278 LYS 278 278 278 LYS LYS A . n 
A 1 279 ALA 279 279 279 ALA ALA A . n 
A 1 280 TYR 280 280 280 TYR TYR A . n 
A 1 281 CYS 281 281 281 CYS CYS A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 PRO 283 283 283 PRO PRO A . n 
A 1 284 LYS 284 284 284 LYS LYS A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 VAL 286 286 286 VAL VAL A . n 
A 1 287 GLU 287 287 287 GLU GLU A . n 
A 1 288 GLY 288 288 288 GLY GLY A . n 
A 1 289 ASN 289 289 289 ASN ASN A . n 
A 1 290 PRO 290 290 290 PRO PRO A . n 
A 1 291 CYS 291 291 291 CYS CYS A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 GLU 293 293 293 GLU GLU A . n 
A 1 294 TYR 294 294 294 TYR TYR A . n 
A 1 295 ILE 295 295 295 ILE ILE A . n 
A 1 296 LYS 296 296 296 LYS LYS A . n 
A 1 297 TYR 297 297 297 TYR TYR A . n 
A 1 298 LEU 298 298 298 LEU LEU A . n 
A 1 299 ILE 299 299 299 ILE ILE A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 PRO 301 301 301 PRO PRO A . n 
A 1 302 TRP 302 302 302 TRP TRP A . n 
A 1 303 PHE 303 303 303 PHE PHE A . n 
A 1 304 ASN 304 304 304 ASN ASN A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 PHE 306 306 306 PHE PHE A . n 
A 1 307 THR 307 307 307 THR THR A . n 
A 1 308 VAL 308 308 308 VAL VAL A . n 
A 1 309 GLU 309 309 309 GLU GLU A . n 
A 1 310 ARG 310 310 310 ARG ARG A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 ALA 312 312 312 ALA ALA A . n 
A 1 313 ASP 313 313 313 ASP ASP A . n 
A 1 314 ASN 314 314 314 ASN ASN A . n 
A 1 315 GLY 315 315 315 GLY GLY A . n 
A 1 316 GLY 316 316 316 GLY GLY A . n 
A 1 317 ASN 317 317 317 ASN ASN A . n 
A 1 318 LYS 318 318 318 LYS LYS A . n 
A 1 319 THR 319 319 319 THR THR A . n 
A 1 320 PHE 320 320 320 PHE PHE A . n 
A 1 321 LYS 321 321 321 LYS LYS A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 TYR 323 323 323 TYR TYR A . n 
A 1 324 GLU 324 324 324 GLU GLU A . n 
A 1 325 GLU 325 325 325 GLU GLU A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 ALA 328 328 328 ALA ALA A . n 
A 1 329 ASP 329 329 329 ASP ASP A . n 
A 1 330 TYR 330 330 330 TYR TYR A . n 
A 1 331 GLU 331 331 331 GLU GLU A . n 
A 1 332 SER 332 332 332 SER SER A . n 
A 1 333 GLY 333 333 333 GLY GLY A . n 
A 1 334 GLU 334 334 334 GLU GLU A . n 
A 1 335 LEU 335 335 335 LEU LEU A . n 
A 1 336 HIS 336 336 336 HIS HIS A . n 
A 1 337 PRO 337 337 337 PRO PRO A . n 
A 1 338 ALA 338 338 338 ALA ALA A . n 
A 1 339 ASP 339 339 339 ASP ASP A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 LYS 341 341 341 LYS LYS A . n 
A 1 342 PRO 342 342 342 PRO PRO A . n 
A 1 343 ALA 343 343 343 ALA ALA A . n 
A 1 344 LEU 344 344 344 LEU LEU A . n 
A 1 345 SER 345 345 345 SER SER A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 ASN 349 349 349 ASN ASN A . n 
A 1 350 LYS 350 350 350 LYS LYS A . n 
A 1 351 ILE 351 351 351 ILE ILE A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 GLU 353 353 353 GLU GLU A . n 
A 1 354 PRO 354 354 354 PRO PRO A . n 
A 1 355 VAL 355 355 355 VAL VAL A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 GLU 357 357 357 GLU GLU A . n 
A 1 358 HIS 358 358 358 HIS HIS A . n 
A 1 359 PHE 359 359 359 PHE PHE A . n 
A 1 360 ARG 360 360 360 ARG ARG A . n 
A 1 361 LYS 361 361 361 LYS LYS A . n 
A 1 362 ASP 362 362 362 ASP ASP A . n 
A 1 363 SER 363 363 363 SER SER A . n 
A 1 364 ASN 364 364 364 ASN ASN A . n 
A 1 365 ALA 365 365 365 ALA ALA A . n 
A 1 366 LYS 366 366 366 LYS LYS A . n 
A 1 367 GLU 367 367 367 GLU GLU A . n 
A 1 368 LEU 368 368 368 LEU LEU A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 LYS 370 370 370 LYS LYS A . n 
A 1 371 ARG 371 371 371 ARG ARG A . n 
A 1 372 VAL 372 372 372 VAL VAL A . n 
A 1 373 LYS 373 373 373 LYS LYS A . n 
A 1 374 ALA 374 374 374 ALA ALA A . n 
A 1 375 TYR 375 375 375 TYR TYR A . n 
A 1 376 ARG 376 376 376 ARG ARG A . n 
A 1 377 VAL 377 377 377 VAL VAL A . n 
A 1 378 THR 378 378 378 THR THR A . n 
A 1 379 LYS 379 379 379 LYS LYS A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   GLU 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   PRO 5   5   ?   ?   ?   B . n 
B 1 6   SER 6   6   ?   ?   ?   B . n 
B 1 7   GLU 7   7   ?   ?   ?   B . n 
B 1 8   ALA 8   8   ?   ?   ?   B . n 
B 1 9   LEU 9   9   ?   ?   ?   B . n 
B 1 10  GLN 10  10  ?   ?   ?   B . n 
B 1 11  SER 11  11  ?   ?   ?   B . n 
B 1 12  LEU 12  12  ?   ?   ?   B . n 
B 1 13  SER 13  13  ?   ?   ?   B . n 
B 1 14  VAL 14  14  ?   ?   ?   B . n 
B 1 15  SER 15  15  ?   ?   ?   B . n 
B 1 16  ASP 16  16  ?   ?   ?   B . n 
B 1 17  SER 17  17  ?   ?   ?   B . n 
B 1 18  GLN 18  18  ?   ?   ?   B . n 
B 1 19  ILE 19  19  ?   ?   ?   B . n 
B 1 20  PRO 20  20  ?   ?   ?   B . n 
B 1 21  GLN 21  21  ?   ?   ?   B . n 
B 1 22  SER 22  22  ?   ?   ?   B . n 
B 1 23  SER 23  23  ?   ?   ?   B . n 
B 1 24  ASN 24  24  ?   ?   ?   B . n 
B 1 25  SER 25  25  ?   ?   ?   B . n 
B 1 26  THR 26  26  ?   ?   ?   B . n 
B 1 27  PRO 27  27  ?   ?   ?   B . n 
B 1 28  GLN 28  28  ?   ?   ?   B . n 
B 1 29  LEU 29  29  ?   ?   ?   B . n 
B 1 30  SER 30  30  ?   ?   ?   B . n 
B 1 31  PRO 31  31  31  PRO PRO B . n 
B 1 32  GLU 32  32  32  GLU GLU B . n 
B 1 33  GLU 33  33  33  GLU GLU B . n 
B 1 34  LYS 34  34  34  LYS LYS B . n 
B 1 35  PHE 35  35  35  PHE PHE B . n 
B 1 36  LYS 36  36  36  LYS LYS B . n 
B 1 37  ILE 37  37  37  ILE ILE B . n 
B 1 38  VAL 38  38  38  VAL VAL B . n 
B 1 39  ARG 39  39  39  ARG ARG B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  GLY 42  42  42  GLY GLY B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  GLU 44  44  44  GLU GLU B . n 
B 1 45  CYS 45  45  45  CYS CYS B . n 
B 1 46  ILE 46  46  46  ILE ILE B . n 
B 1 47  GLN 47  47  47  GLN GLN B . n 
B 1 48  GLU 48  48  48  GLU GLU B . n 
B 1 49  ASP 49  49  49  ASP ASP B . n 
B 1 50  GLU 50  50  50  GLU GLU B . n 
B 1 51  LEU 51  51  51  LEU LEU B . n 
B 1 52  LEU 52  52  52  LEU LEU B . n 
B 1 53  ASN 53  53  53  ASN ASN B . n 
B 1 54  LEU 54  54  54  LEU LEU B . n 
B 1 55  LEU 55  55  55  LEU LEU B . n 
B 1 56  THR 56  56  56  THR THR B . n 
B 1 57  LYS 57  57  57  LYS LYS B . n 
B 1 58  LYS 58  58  58  LYS LYS B . n 
B 1 59  PRO 59  59  59  PRO PRO B . n 
B 1 60  GLU 60  60  60  GLU GLU B . n 
B 1 61  PRO 61  61  61  PRO PRO B . n 
B 1 62  VAL 62  62  62  VAL VAL B . n 
B 1 63  CYS 63  63  63  CYS CYS B . n 
B 1 64  TYR 64  64  64  TYR TYR B . n 
B 1 65  ASP 65  65  65  ASP ASP B . n 
B 1 66  GLY 66  66  66  GLY GLY B . n 
B 1 67  PHE 67  67  67  PHE PHE B . n 
B 1 68  GLU 68  68  68  GLU GLU B . n 
B 1 69  PRO 69  69  69  PRO PRO B . n 
B 1 70  SER 70  70  70  SER SER B . n 
B 1 71  GLY 71  71  71  GLY GLY B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  MET 73  73  73  MET MET B . n 
B 1 74  HIS 74  74  74  HIS HIS B . n 
B 1 75  ILE 75  75  75  ILE ILE B . n 
B 1 76  ALA 76  76  76  ALA ALA B . n 
B 1 77  GLN 77  77  77  GLN GLN B . n 
B 1 78  GLY 78  78  78  GLY GLY B . n 
B 1 79  VAL 79  79  79  VAL VAL B . n 
B 1 80  MET 80  80  80  MET MET B . n 
B 1 81  LYS 81  81  81  LYS LYS B . n 
B 1 82  THR 82  82  82  THR THR B . n 
B 1 83  ILE 83  83  83  ILE ILE B . n 
B 1 84  SER 84  84  84  SER SER B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  ASN 86  86  86  ASN ASN B . n 
B 1 87  LYS 87  87  87  LYS LYS B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  THR 89  89  89  THR THR B . n 
B 1 90  SER 90  90  90  SER SER B . n 
B 1 91  ALA 91  91  91  ALA ALA B . n 
B 1 92  GLY 92  92  92  GLY GLY B . n 
B 1 93  CYS 93  93  93  CYS CYS B . n 
B 1 94  ARG 94  94  94  ARG ARG B . n 
B 1 95  VAL 95  95  95  VAL VAL B . n 
B 1 96  LYS 96  96  96  LYS LYS B . n 
B 1 97  ILE 97  97  97  ILE ILE B . n 
B 1 98  TRP 98  98  98  TRP TRP B . n 
B 1 99  ILE 99  99  99  ILE ILE B . n 
B 1 100 ALA 100 100 100 ALA ALA B . n 
B 1 101 ASP 101 101 101 ASP ASP B . n 
B 1 102 TRP 102 102 102 TRP TRP B . n 
B 1 103 PHE 103 103 103 PHE PHE B . n 
B 1 104 ALA 104 104 104 ALA ALA B . n 
B 1 105 LYS 105 105 105 LYS LYS B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 ASN 107 107 107 ASN ASN B . n 
B 1 108 ASN 108 108 108 ASN ASN B . n 
B 1 109 LYS 109 109 109 LYS LYS B . n 
B 1 110 MET 110 110 110 MET MET B . n 
B 1 111 GLY 111 111 111 GLY GLY B . n 
B 1 112 GLY 112 112 112 GLY GLY B . n 
B 1 113 ASP 113 113 113 ASP ASP B . n 
B 1 114 LEU 114 114 114 LEU LEU B . n 
B 1 115 LYS 115 115 115 LYS LYS B . n 
B 1 116 LYS 116 116 116 LYS LYS B . n 
B 1 117 ILE 117 117 117 ILE ILE B . n 
B 1 118 GLU 118 118 118 GLU GLU B . n 
B 1 119 THR 119 119 119 THR THR B . n 
B 1 120 VAL 120 120 120 VAL VAL B . n 
B 1 121 GLY 121 121 121 GLY GLY B . n 
B 1 122 ARG 122 122 122 ARG ARG B . n 
B 1 123 TYR 123 123 123 TYR TYR B . n 
B 1 124 LEU 124 124 124 LEU LEU B . n 
B 1 125 ILE 125 125 125 ILE ILE B . n 
B 1 126 GLU 126 126 126 GLU GLU B . n 
B 1 127 ILE 127 127 127 ILE ILE B . n 
B 1 128 TRP 128 128 128 TRP TRP B . n 
B 1 129 LYS 129 129 129 LYS LYS B . n 
B 1 130 ALA 130 130 130 ALA ALA B . n 
B 1 131 VAL 131 131 131 VAL VAL B . n 
B 1 132 GLY 132 132 132 GLY GLY B . n 
B 1 133 MET 133 133 133 MET MET B . n 
B 1 134 ASP 134 134 134 ASP ASP B . n 
B 1 135 VAL 135 135 135 VAL VAL B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 LYS 139 139 139 LYS LYS B . n 
B 1 140 VAL 140 140 140 VAL VAL B . n 
B 1 141 GLU 141 141 141 GLU GLU B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 LEU 143 143 143 LEU LEU B . n 
B 1 144 TRP 144 144 144 TRP TRP B . n 
B 1 145 SER 145 145 145 SER SER B . n 
B 1 146 SER 146 146 146 SER SER B . n 
B 1 147 LYS 147 147 147 LYS LYS B . n 
B 1 148 GLU 148 148 148 GLU GLU B . n 
B 1 149 ILE 149 149 149 ILE ILE B . n 
B 1 150 ASN 150 150 150 ASN ASN B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 ARG 152 152 152 ARG ARG B . n 
B 1 153 ALA 153 153 153 ALA ALA B . n 
B 1 154 ASP 154 154 154 ASP ASP B . n 
B 1 155 GLU 155 155 155 GLU GLU B . n 
B 1 156 TYR 156 156 156 TYR TYR B . n 
B 1 157 TRP 157 157 157 TRP TRP B . n 
B 1 158 PRO 158 158 158 PRO PRO B . n 
B 1 159 LEU 159 159 159 LEU LEU B . n 
B 1 160 VAL 160 160 160 VAL VAL B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 ASP 162 162 162 ASP ASP B . n 
B 1 163 ILE 163 163 163 ILE ILE B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 GLN 165 165 165 GLN GLN B . n 
B 1 166 LYS 166 166 166 LYS LYS B . n 
B 1 167 ASN 167 167 167 ASN ASN B . n 
B 1 168 ASN 168 168 168 ASN ASN B . n 
B 1 169 LEU 169 169 169 LEU LEU B . n 
B 1 170 LYS 170 170 170 LYS LYS B . n 
B 1 171 ARG 171 171 171 ARG ARG B . n 
B 1 172 ILE 172 172 172 ILE ILE B . n 
B 1 173 ILE 173 173 173 ILE ILE B . n 
B 1 174 ARG 174 174 174 ARG ARG B . n 
B 1 175 CYS 175 175 175 CYS CYS B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 GLN 177 177 177 GLN GLN B . n 
B 1 178 ILE 178 178 178 ILE ILE B . n 
B 1 179 MET 179 179 179 MET MET B . n 
B 1 180 GLY 180 180 180 GLY GLY B . n 
B 1 181 ARG 181 181 181 ARG ARG B . n 
B 1 182 SER 182 182 182 SER SER B . n 
B 1 183 GLU 183 183 183 GLU GLU B . n 
B 1 184 GLN 184 184 184 GLN GLN B . n 
B 1 185 ASP 185 185 185 ASP ASP B . n 
B 1 186 GLU 186 186 186 GLU GLU B . n 
B 1 187 LEU 187 187 187 LEU LEU B . n 
B 1 188 THR 188 188 188 THR THR B . n 
B 1 189 ALA 189 189 189 ALA ALA B . n 
B 1 190 ALA 190 190 190 ALA ALA B . n 
B 1 191 GLN 191 191 191 GLN GLN B . n 
B 1 192 ILE 192 192 192 ILE ILE B . n 
B 1 193 PHE 193 193 193 PHE PHE B . n 
B 1 194 TYR 194 194 194 TYR TYR B . n 
B 1 195 PRO 195 195 195 PRO PRO B . n 
B 1 196 CYS 196 196 196 CYS CYS B . n 
B 1 197 MET 197 197 197 MET MET B . n 
B 1 198 GLN 198 198 198 GLN GLN B . n 
B 1 199 CYS 199 199 199 CYS CYS B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 ASP 201 201 201 ASP ASP B . n 
B 1 202 ILE 202 202 202 ILE ILE B . n 
B 1 203 PHE 203 203 203 PHE PHE B . n 
B 1 204 PHE 204 204 204 PHE PHE B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 LYS 206 206 206 LYS LYS B . n 
B 1 207 ALA 207 207 207 ALA ALA B . n 
B 1 208 ASP 208 208 208 ASP ASP B . n 
B 1 209 ILE 209 209 209 ILE ILE B . n 
B 1 210 CYS 210 210 210 CYS CYS B . n 
B 1 211 GLN 211 211 211 GLN GLN B . n 
B 1 212 LEU 212 212 212 LEU LEU B . n 
B 1 213 GLY 213 213 213 GLY GLY B . n 
B 1 214 MET 214 214 214 MET MET B . n 
B 1 215 ASP 215 215 215 ASP ASP B . n 
B 1 216 GLN 216 216 216 GLN GLN B . n 
B 1 217 ARG 217 217 217 ARG ARG B . n 
B 1 218 LYS 218 218 218 LYS LYS B . n 
B 1 219 VAL 219 219 219 VAL VAL B . n 
B 1 220 ASN 220 220 220 ASN ASN B . n 
B 1 221 VAL 221 221 221 VAL VAL B . n 
B 1 222 LEU 222 222 222 LEU LEU B . n 
B 1 223 ALA 223 223 223 ALA ALA B . n 
B 1 224 ARG 224 224 224 ARG ARG B . n 
B 1 225 GLU 225 225 225 GLU GLU B . n 
B 1 226 TYR 226 226 226 TYR TYR B . n 
B 1 227 CYS 227 227 227 CYS CYS B . n 
B 1 228 ASP 228 228 228 ASP ASP B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 ILE 230 230 230 ILE ILE B . n 
B 1 231 LYS 231 231 231 LYS LYS B . n 
B 1 232 ARG 232 232 232 ARG ARG B . n 
B 1 233 LYS 233 233 233 LYS LYS B . n 
B 1 234 ASN 234 234 234 ASN ASN B . n 
B 1 235 LYS 235 235 235 LYS LYS B . n 
B 1 236 PRO 236 236 236 PRO PRO B . n 
B 1 237 ILE 237 237 237 ILE ILE B . n 
B 1 238 ILE 238 238 238 ILE ILE B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 SER 240 240 240 SER SER B . n 
B 1 241 HIS 241 241 241 HIS HIS B . n 
B 1 242 HIS 242 242 242 HIS HIS B . n 
B 1 243 MET 243 243 243 MET MET B . n 
B 1 244 LEU 244 244 244 LEU LEU B . n 
B 1 245 PRO 245 245 245 PRO PRO B . n 
B 1 246 GLY 246 246 246 GLY GLY B . n 
B 1 247 LEU 247 247 247 LEU LEU B . n 
B 1 248 GLN 248 248 248 GLN GLN B . n 
B 1 249 GLN 249 249 249 GLN GLN B . n 
B 1 250 GLY 250 250 250 GLY GLY B . n 
B 1 251 GLN 251 251 251 GLN GLN B . n 
B 1 252 GLU 252 252 252 GLU GLU B . n 
B 1 253 LYS 253 253 253 LYS LYS B . n 
B 1 254 MET 254 254 254 MET MET B . n 
B 1 255 SER 255 255 255 SER SER B . n 
B 1 256 LYS 256 256 256 LYS LYS B . n 
B 1 257 SER 257 257 257 SER SER B . n 
B 1 258 ASP 258 258 258 ASP ASP B . n 
B 1 259 PRO 259 259 259 PRO PRO B . n 
B 1 260 SER 260 260 260 SER SER B . n 
B 1 261 SER 261 261 261 SER SER B . n 
B 1 262 SER 262 262 262 SER SER B . n 
B 1 263 VAL 263 263 263 VAL VAL B . n 
B 1 264 PHE 264 264 264 PHE PHE B . n 
B 1 265 MET 265 265 265 MET MET B . n 
B 1 266 GLU 266 266 266 GLU GLU B . n 
B 1 267 ASP 267 267 267 ASP ASP B . n 
B 1 268 GLU 268 268 268 GLU GLU B . n 
B 1 269 GLU 269 269 269 GLU GLU B . n 
B 1 270 ALA 270 270 270 ALA ALA B . n 
B 1 271 GLU 271 271 271 GLU GLU B . n 
B 1 272 VAL 272 272 272 VAL VAL B . n 
B 1 273 ASN 273 273 273 ASN ASN B . n 
B 1 274 VAL 274 274 274 VAL VAL B . n 
B 1 275 LYS 275 275 275 LYS LYS B . n 
B 1 276 ILE 276 276 276 ILE ILE B . n 
B 1 277 LYS 277 277 277 LYS LYS B . n 
B 1 278 LYS 278 278 278 LYS LYS B . n 
B 1 279 ALA 279 279 279 ALA ALA B . n 
B 1 280 TYR 280 280 280 TYR TYR B . n 
B 1 281 CYS 281 281 281 CYS CYS B . n 
B 1 282 PRO 282 282 282 PRO PRO B . n 
B 1 283 PRO 283 283 283 PRO PRO B . n 
B 1 284 LYS 284 284 284 LYS LYS B . n 
B 1 285 VAL 285 285 285 VAL VAL B . n 
B 1 286 VAL 286 286 286 VAL VAL B . n 
B 1 287 GLU 287 287 287 GLU GLU B . n 
B 1 288 GLY 288 288 288 GLY GLY B . n 
B 1 289 ASN 289 289 289 ASN ASN B . n 
B 1 290 PRO 290 290 290 PRO PRO B . n 
B 1 291 CYS 291 291 291 CYS CYS B . n 
B 1 292 LEU 292 292 292 LEU LEU B . n 
B 1 293 GLU 293 293 293 GLU GLU B . n 
B 1 294 TYR 294 294 294 TYR TYR B . n 
B 1 295 ILE 295 295 295 ILE ILE B . n 
B 1 296 LYS 296 296 296 LYS LYS B . n 
B 1 297 TYR 297 297 297 TYR TYR B . n 
B 1 298 LEU 298 298 298 LEU LEU B . n 
B 1 299 ILE 299 299 299 ILE ILE B . n 
B 1 300 LEU 300 300 300 LEU LEU B . n 
B 1 301 PRO 301 301 301 PRO PRO B . n 
B 1 302 TRP 302 302 302 TRP TRP B . n 
B 1 303 PHE 303 303 303 PHE PHE B . n 
B 1 304 ASN 304 304 304 ASN ASN B . n 
B 1 305 GLU 305 305 305 GLU GLU B . n 
B 1 306 PHE 306 306 306 PHE PHE B . n 
B 1 307 THR 307 307 307 THR THR B . n 
B 1 308 VAL 308 308 308 VAL VAL B . n 
B 1 309 GLU 309 309 309 GLU GLU B . n 
B 1 310 ARG 310 310 310 ARG ARG B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 ALA 312 312 312 ALA ALA B . n 
B 1 313 ASP 313 313 313 ASP ASP B . n 
B 1 314 ASN 314 314 314 ASN ASN B . n 
B 1 315 GLY 315 315 315 GLY GLY B . n 
B 1 316 GLY 316 316 316 GLY GLY B . n 
B 1 317 ASN 317 317 317 ASN ASN B . n 
B 1 318 LYS 318 318 318 LYS LYS B . n 
B 1 319 THR 319 319 319 THR THR B . n 
B 1 320 PHE 320 320 320 PHE PHE B . n 
B 1 321 LYS 321 321 321 LYS LYS B . n 
B 1 322 SER 322 322 322 SER SER B . n 
B 1 323 TYR 323 323 323 TYR TYR B . n 
B 1 324 GLU 324 324 324 GLU GLU B . n 
B 1 325 GLU 325 325 325 GLU GLU B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 ILE 327 327 327 ILE ILE B . n 
B 1 328 ALA 328 328 328 ALA ALA B . n 
B 1 329 ASP 329 329 329 ASP ASP B . n 
B 1 330 TYR 330 330 330 TYR TYR B . n 
B 1 331 GLU 331 331 331 GLU GLU B . n 
B 1 332 SER 332 332 332 SER SER B . n 
B 1 333 GLY 333 333 333 GLY GLY B . n 
B 1 334 GLU 334 334 334 GLU GLU B . n 
B 1 335 LEU 335 335 335 LEU LEU B . n 
B 1 336 HIS 336 336 336 HIS HIS B . n 
B 1 337 PRO 337 337 337 PRO PRO B . n 
B 1 338 ALA 338 338 338 ALA ALA B . n 
B 1 339 ASP 339 339 339 ASP ASP B . n 
B 1 340 LEU 340 340 340 LEU LEU B . n 
B 1 341 LYS 341 341 341 LYS LYS B . n 
B 1 342 PRO 342 342 342 PRO PRO B . n 
B 1 343 ALA 343 343 343 ALA ALA B . n 
B 1 344 LEU 344 344 344 LEU LEU B . n 
B 1 345 SER 345 345 345 SER SER B . n 
B 1 346 LYS 346 346 346 LYS LYS B . n 
B 1 347 SER 347 347 347 SER SER B . n 
B 1 348 LEU 348 348 348 LEU LEU B . n 
B 1 349 ASN 349 349 349 ASN ASN B . n 
B 1 350 LYS 350 350 350 LYS LYS B . n 
B 1 351 ILE 351 351 351 ILE ILE B . n 
B 1 352 LEU 352 352 352 LEU LEU B . n 
B 1 353 GLU 353 353 353 GLU GLU B . n 
B 1 354 PRO 354 354 354 PRO PRO B . n 
B 1 355 VAL 355 355 355 VAL VAL B . n 
B 1 356 ARG 356 356 356 ARG ARG B . n 
B 1 357 GLU 357 357 357 GLU GLU B . n 
B 1 358 HIS 358 358 358 HIS HIS B . n 
B 1 359 PHE 359 359 359 PHE PHE B . n 
B 1 360 ARG 360 360 360 ARG ARG B . n 
B 1 361 LYS 361 361 361 LYS LYS B . n 
B 1 362 ASP 362 362 362 ASP ASP B . n 
B 1 363 SER 363 363 363 SER SER B . n 
B 1 364 ASN 364 364 364 ASN ASN B . n 
B 1 365 ALA 365 365 365 ALA ALA B . n 
B 1 366 LYS 366 366 366 LYS LYS B . n 
B 1 367 GLU 367 367 367 GLU GLU B . n 
B 1 368 LEU 368 368 368 LEU LEU B . n 
B 1 369 LEU 369 369 369 LEU LEU B . n 
B 1 370 LYS 370 370 370 LYS LYS B . n 
B 1 371 ARG 371 371 371 ARG ARG B . n 
B 1 372 VAL 372 372 372 VAL VAL B . n 
B 1 373 LYS 373 373 373 LYS LYS B . n 
B 1 374 ALA 374 374 374 ALA ALA B . n 
B 1 375 TYR 375 375 375 TYR TYR B . n 
B 1 376 ARG 376 376 376 ARG ARG B . n 
B 1 377 VAL 377 377 377 VAL VAL B . n 
B 1 378 THR 378 378 378 THR THR B . n 
B 1 379 LYS 379 379 379 LYS LYS B . n 
C 2 1   C   1   1   1   C   C   C . n 
C 2 2   G   2   2   2   G   G   C . n 
C 2 3   U   3   3   3   U   U   C . n 
C 2 4   G   4   4   4   G   G   C . n 
C 2 5   G   5   5   5   G   G   C . n 
C 2 6   U   6   6   6   U   U   C . n 
C 2 7   U   7   7   7   U   U   C . n 
C 2 8   G   8   8   8   G   G   C . n 
C 2 9   A   9   9   9   A   A   C . n 
C 2 10  C   10  10  10  C   C   C . n 
C 2 11  A   11  11  11  A   A   C . n 
C 2 12  C   12  12  12  C   C   C . n 
C 2 13  G   13  13  13  G   G   C . n 
C 2 14  C   14  14  14  C   C   C . n 
C 2 15  A   15  15  15  A   A   C . n 
C 2 16  G   16  16  16  G   G   C . n 
C 2 17  A   17  17  17  A   A   C . n 
C 2 18  C   18  18  18  C   C   C . n 
C 2 19  C   19  19  19  C   C   C . n 
C 2 20  U   20  20  20  U   U   C . n 
C 2 21  C   21  21  21  C   C   C . n 
C 2 22  U   22  22  22  U   U   C . n 
C 2 23  U   23  23  23  U   U   C . n 
C 2 24  A   24  24  24  A   A   C . n 
C 2 25  C   25  25  25  C   C   C . n 
C 2 26  A   26  26  26  A   A   C . n 
C 2 27  A   27  27  27  A   A   C . n 
C 2 28  G   28  28  28  G   G   C . n 
C 2 29  A   29  29  29  A   A   C . n 
C 2 30  G   30  30  30  G   G   C . n 
C 2 31  U   31  31  31  U   U   C . n 
C 2 32  G   32  32  32  G   G   C . n 
C 2 33  U   33  33  33  U   U   C . n 
C 2 34  C   34  34  34  C   C   C . n 
C 2 35  U   35  35  35  U   U   C . n 
C 2 36  A   36  36  36  A   A   C . n 
C 2 37  G   37  37  37  G   G   C . n 
C 2 38  G   38  38  38  G   G   C . n 
C 2 39  U   39  39  39  U   U   C . n 
C 2 40  G   40  40  40  G   G   C . n 
C 2 41  C   41  41  41  C   C   C . n 
C 2 42  C   42  42  42  C   C   C . n 
C 2 43  U   43  43  43  U   U   C . n 
C 2 44  U   44  44  44  U   U   C . n 
C 2 45  U   45  45  45  U   U   C . n 
C 2 46  G   46  46  46  G   G   C . n 
C 2 47  A   47  47  47  A   A   C . n 
C 2 48  G   48  48  48  G   G   C . n 
C 2 49  A   49  49  49  A   A   C . n 
C 2 50  G   50  50  50  G   G   C . n 
C 2 51  U   51  51  51  U   U   C . n 
C 2 52  U   52  52  52  U   U   C . n 
C 2 53  A   53  53  53  A   A   C . n 
C 2 54  C   54  54  54  C   C   C . n 
C 2 55  U   55  55  55  U   U   C . n 
C 2 56  C   56  56  56  C   C   C . n 
C 2 57  U   57  57  57  U   U   C . n 
C 2 58  U   58  58  58  U   U   C . n 
C 2 59  U   59  59  59  U   U   C . n 
C 2 60  G   60  60  60  G   G   C . n 
C 2 61  C   61  61  61  C   C   C . n 
C 2 62  U   62  62  62  U   U   C . n 
C 2 63  C   63  63  63  C   C   C . n 
C 2 64  U   64  64  64  U   U   C . n 
C 2 65  C   65  65  65  C   C   C . n 
C 2 66  U   66  66  66  U   U   C . n 
C 2 67  U   67  67  67  U   U   C . n 
C 2 68  C   68  68  68  C   C   C . n 
C 2 69  G   69  69  69  G   G   C . n 
C 2 70  G   70  70  70  G   G   C . n 
C 2 71  A   71  71  71  A   A   C . n 
C 2 72  A   72  72  72  A   A   C . n 
C 2 73  G   73  73  73  G   G   C . n 
C 2 74  A   74  74  74  A   A   C . n 
C 2 75  A   75  75  75  A   A   C . n 
C 2 76  C   76  76  76  C   C   C . n 
C 2 77  C   77  77  77  C   C   C . n 
C 2 78  C   78  78  78  C   C   C . n 
C 2 79  U   79  79  79  U   U   C . n 
C 2 80  U   80  80  80  U   U   C . n 
C 2 81  A   81  81  81  A   A   C . n 
C 2 82  G   82  82  82  G   G   C . n 
C 2 83  G   83  83  83  G   G   C . n 
C 2 84  G   84  84  84  G   G   C . n 
C 2 85  G   85  85  85  G   G   C . n 
C 2 86  U   86  86  86  U   U   C . n 
C 2 87  U   87  87  87  U   U   C . n 
C 2 88  C   88  88  88  C   C   C . n 
C 2 89  G   89  89  89  G   G   C . n 
C 2 90  U   90  90  90  U   U   C . n 
C 2 91  G   91  91  91  G   G   C . n 
C 2 92  C   92  92  92  C   C   C . n 
C 2 93  A   93  93  93  A   A   C . n 
C 2 94  U   94  94  94  U   U   C . n 
C 2 95  G   95  95  95  G   G   C . n 
C 2 96  G   96  96  96  G   G   C . n 
C 2 97  G   97  97  97  G   G   C . n 
C 2 98  C   98  98  98  C   C   C . n 
C 2 99  U   99  99  99  U   U   C . n 
C 2 100 U   100 100 100 U   U   C . n 
C 2 101 G   101 101 101 G   G   C . n 
C 2 102 C   102 102 102 C   C   C . n 
C 2 103 A   103 103 103 A   A   C . n 
C 2 104 U   104 104 104 U   U   C . n 
C 2 105 A   105 105 105 A   A   C . n 
C 2 106 G   106 106 106 G   G   C . n 
C 2 107 C   107 107 107 C   C   C . n 
C 2 108 A   108 108 108 A   A   C . n 
C 2 109 A   109 109 109 A   A   C . n 
C 2 110 G   110 110 110 G   G   C . n 
C 2 111 U   111 111 111 U   U   C . n 
C 2 112 C   112 112 112 C   C   C . n 
C 2 113 U   113 113 113 U   U   C . n 
C 2 114 U   114 114 114 U   U   C . n 
C 2 115 A   115 115 115 A   A   C . n 
C 2 116 G   116 116 116 G   G   C . n 
C 2 117 A   117 117 117 A   A   C . n 
C 2 118 A   118 118 118 A   A   C . n 
C 2 119 U   119 119 119 U   U   C . n 
C 2 120 G   120 120 120 G   G   C . n 
C 2 121 C   121 121 121 C   C   C . n 
C 2 122 G   122 122 122 G   G   C . n 
C 2 123 G   123 123 123 G   G   C . n 
C 2 124 G   124 124 124 G   G   C . n 
C 2 125 U   125 125 125 U   U   C . n 
C 2 126 A   126 126 126 A   A   C . n 
C 2 127 C   127 127 127 C   C   C . n 
C 2 128 C   128 128 128 C   C   C . n 
C 2 129 G   129 129 129 G   G   C . n 
C 2 130 U   130 130 130 U   U   C . n 
C 2 131 A   131 131 131 A   A   C . n 
C 2 132 C   132 132 132 C   C   C . n 
C 2 133 A   133 133 133 A   A   C . n 
C 2 134 G   134 134 134 G   G   C . n 
C 2 135 U   135 135 135 U   U   C . n 
C 2 136 G   136 136 136 G   G   C . n 
C 2 137 U   137 137 137 U   U   C . n 
C 2 138 U   138 138 138 U   U   C . n 
C 2 139 G   139 139 139 G   G   C . n 
C 2 140 A   140 140 140 A   A   C . n 
C 2 141 A   141 141 141 A   A   C . n 
C 2 142 A   142 142 142 A   A   C . n 
C 2 143 A   143 143 143 A   A   C . n 
C 2 144 A   144 144 144 A   A   C . n 
C 2 145 C   145 145 145 C   C   C . n 
C 2 146 A   146 146 146 A   A   C . n 
C 2 147 C   147 147 147 C   C   C . n 
C 2 148 U   148 148 148 U   U   C . n 
C 2 149 G   149 149 149 G   G   C . n 
C 2 150 U   150 150 150 U   U   C . n 
C 2 151 A   151 151 151 A   A   C . n 
C 2 152 A   152 152 152 A   A   C . n 
C 2 153 A   153 153 153 A   A   C . n 
C 2 154 U   154 154 154 U   U   C . n 
C 2 155 C   155 155 155 C   C   C . n 
C 2 156 U   156 156 156 U   U   C . n 
C 2 157 C   157 157 157 C   C   C . n 
C 2 158 U   158 158 158 U   U   C . n 
C 2 159 A   159 159 159 A   A   C . n 
C 2 160 A   160 160 160 A   A   C . n 
C 2 161 A   161 161 161 A   A   C . n 
C 2 162 A   162 162 162 A   A   C . n 
C 2 163 G   163 163 163 G   G   C . n 
C 2 164 A   164 164 164 A   A   C . n 
C 2 165 G   165 165 165 G   G   C . n 
C 2 166 A   166 166 166 A   A   C . n 
C 2 167 C   167 167 167 C   C   C . n 
C 2 168 C   168 168 168 C   C   C . n 
C 2 169 A   169 169 169 A   A   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ATP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ATP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         D 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          ATP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      ATP 
_pdbx_nonpoly_scheme.auth_mon_id     ATP 
_pdbx_nonpoly_scheme.pdb_strand_id   B 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZMI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZMI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZMI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ZMI 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 9771  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.527  ? 14005 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 16.344 ? 2779  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.033  ? 1678  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005  ? 1158  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZMI 
_struct.title                        'Cryo-EM structure of BMV TLS-TyrRS-ATP(Pre-1a state)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZMI 
_struct_keywords.text            
'Brome osaic Virus, tRNA-like structure, aminoacylation, tyrosyl-tRNA synthetase, LIGASE/RNA, LIGASE-RNA complex' 
_struct_keywords.pdbx_keywords   LIGASE/RNA 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP V7CJ18_PHAVU V7CJ18 ? 1 
;MEQAPSEALQSLSVSDSQIPQSSNSTPQLSPEEKFKIVRSVGEECIQEDELLNLLTKKPEPVCYDGFEPSGRMHIAQGVM
KTISVNKLTSAGCRVKIWIADWFAKLNNKMGGDLKKIETVGRYLIEIWKAVGMDVEGGKVEFLWSSKEINARADEYWPLV
LDIAQKNNLKRIIRCSQIMGRSEQDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCDDIKRKNKPIILS
HHMLPGLQQGQEKMSKSDPSSSVFMEDEEAEVNVKIKKAYCPPKVVEGNPCLEYIKYLILPWFNEFTVERSADNGGNKTF
KSYEELIADYESGELHPADLKPALSKSLNKILEPVREHFRKDSNAKELLKRVKAYRVTK
;
1    
2 GB  X58457.1     556693 ? 2 
;CGUGGUUGACACGCAGACCUCUUACAAGAGUGUCUAGGUGCCUUUGAGAGUUACUCUUUGCUCUCUUCGGAAGAACCCUU
AGGGGUUCGUGCAUGGGCUUGCAUAGCAAGUCUUAGAAUGCGGGUACCGUACAGUGUUGAAAAACACUGUAAAUCUCUAA
AAGAGACCA
;
2699 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZMI A 1 ? 379 ? V7CJ18 1    ? 379  ? 1 379 
2 1 8ZMI B 1 ? 379 ? V7CJ18 1    ? 379  ? 1 379 
3 2 8ZMI C 1 ? 169 ? 556693 2699 ? 2867 ? 1 169 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 31  ? SER A 40  ? PRO A 31  SER A 40  1 ? 10 
HELX_P HELX_P2  AA2 GLN A 47  ? LYS A 58  ? GLN A 47  LYS A 58  1 ? 12 
HELX_P HELX_P3  AA3 HIS A 74  ? ALA A 91  ? HIS A 74  ALA A 91  1 ? 18 
HELX_P HELX_P4  AA4 ALA A 100 ? ASN A 107 ? ALA A 100 ASN A 107 1 ? 8  
HELX_P HELX_P5  AA5 LYS A 109 ? GLY A 112 ? LYS A 109 GLY A 112 5 ? 4  
HELX_P HELX_P6  AA6 ASP A 113 ? GLY A 132 ? ASP A 113 GLY A 132 1 ? 20 
HELX_P HELX_P7  AA7 SER A 145 ? ARG A 152 ? SER A 145 ARG A 152 1 ? 8  
HELX_P HELX_P8  AA8 ARG A 152 ? ASN A 167 ? ARG A 152 ASN A 167 1 ? 16 
HELX_P HELX_P9  AA9 ASN A 168 ? ARG A 174 ? ASN A 168 ARG A 174 1 ? 7  
HELX_P HELX_P10 AB1 ALA A 189 ? LYS A 206 ? ALA A 189 LYS A 206 1 ? 18 
HELX_P HELX_P11 AB2 GLN A 216 ? ILE A 230 ? GLN A 216 ILE A 230 1 ? 15 
HELX_P HELX_P12 AB3 GLU A 268 ? ALA A 279 ? GLU A 268 ALA A 279 1 ? 12 
HELX_P HELX_P13 AB4 ASN A 289 ? ASN A 304 ? ASN A 289 ASN A 304 1 ? 16 
HELX_P HELX_P14 AB5 SER A 322 ? GLY A 333 ? SER A 322 GLY A 333 1 ? 12 
HELX_P HELX_P15 AB6 HIS A 336 ? ASP A 362 ? HIS A 336 ASP A 362 1 ? 27 
HELX_P HELX_P16 AB7 ASP A 362 ? TYR A 375 ? ASP A 362 TYR A 375 1 ? 14 
HELX_P HELX_P17 AB8 GLU B 32  ? SER B 40  ? GLU B 32  SER B 40  1 ? 9  
HELX_P HELX_P18 AB9 GLN B 47  ? LYS B 58  ? GLN B 47  LYS B 58  1 ? 12 
HELX_P HELX_P19 AC1 HIS B 74  ? GLY B 92  ? HIS B 74  GLY B 92  1 ? 19 
HELX_P HELX_P20 AC2 ALA B 100 ? ASN B 107 ? ALA B 100 ASN B 107 1 ? 8  
HELX_P HELX_P21 AC3 ASN B 108 ? GLY B 112 ? ASN B 108 GLY B 112 5 ? 5  
HELX_P HELX_P22 AC4 ASP B 113 ? GLY B 132 ? ASP B 113 GLY B 132 1 ? 20 
HELX_P HELX_P23 AC5 ASP B 134 ? GLY B 138 ? ASP B 134 GLY B 138 5 ? 5  
HELX_P HELX_P24 AC6 SER B 145 ? ARG B 152 ? SER B 145 ARG B 152 1 ? 8  
HELX_P HELX_P25 AC7 TYR B 156 ? ASN B 167 ? TYR B 156 ASN B 167 1 ? 12 
HELX_P HELX_P26 AC8 ASN B 168 ? SER B 176 ? ASN B 168 SER B 176 1 ? 9  
HELX_P HELX_P27 AC9 ALA B 189 ? LEU B 205 ? ALA B 189 LEU B 205 1 ? 17 
HELX_P HELX_P28 AD1 GLY B 213 ? ASP B 215 ? GLY B 213 ASP B 215 5 ? 3  
HELX_P HELX_P29 AD2 GLN B 216 ? ILE B 230 ? GLN B 216 ILE B 230 1 ? 15 
HELX_P HELX_P30 AD3 GLU B 268 ? LYS B 278 ? GLU B 268 LYS B 278 1 ? 11 
HELX_P HELX_P31 AD4 ASN B 289 ? ASN B 304 ? ASN B 289 ASN B 304 1 ? 16 
HELX_P HELX_P32 AD5 SER B 311 ? GLY B 315 ? SER B 311 GLY B 315 5 ? 5  
HELX_P HELX_P33 AD6 SER B 322 ? GLY B 333 ? SER B 322 GLY B 333 1 ? 12 
HELX_P HELX_P34 AD7 HIS B 336 ? ASP B 362 ? HIS B 336 ASP B 362 1 ? 27 
HELX_P HELX_P35 AD8 ASP B 362 ? TYR B 375 ? ASP B 362 TYR B 375 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1   hydrog ? ? C C 1   N3 ? ? ? 1_555 C G 13  N1 ? ? C C 1   C G 13  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog2   hydrog ? ? C C 1   N4 ? ? ? 1_555 C G 13  O6 ? ? C C 1   C G 13  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog3   hydrog ? ? C C 1   O2 ? ? ? 1_555 C G 13  N2 ? ? C C 1   C G 13  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog4   hydrog ? ? C G 2   N1 ? ? ? 1_555 C C 12  N3 ? ? C G 2   C C 12  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog5   hydrog ? ? C G 2   N2 ? ? ? 1_555 C C 12  O2 ? ? C G 2   C C 12  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog6   hydrog ? ? C G 2   O6 ? ? ? 1_555 C C 12  N4 ? ? C G 2   C C 12  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog7   hydrog ? ? C U 3   N3 ? ? ? 1_555 C A 11  N1 ? ? C U 3   C A 11  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog8   hydrog ? ? C U 3   O4 ? ? ? 1_555 C A 11  N6 ? ? C U 3   C A 11  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog9   hydrog ? ? C G 4   N1 ? ? ? 1_555 C C 10  N3 ? ? C G 4   C C 10  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog10  hydrog ? ? C G 4   N2 ? ? ? 1_555 C C 10  O2 ? ? C G 4   C C 10  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog11  hydrog ? ? C G 4   O6 ? ? ? 1_555 C C 10  N4 ? ? C G 4   C C 10  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog12  hydrog ? ? C G 5   N2 ? ? ? 1_555 C A 9   N7 ? ? C G 5   C A 9   1_555 ? ? ? ? ? ? TYPE_11_PAIR  ? ? ? 
hydrog13  hydrog ? ? C G 5   N3 ? ? ? 1_555 C A 9   N6 ? ? C G 5   C A 9   1_555 ? ? ? ? ? ? TYPE_11_PAIR  ? ? ? 
hydrog14  hydrog ? ? C A 15  N1 ? ? ? 1_555 C U 35  N3 ? ? C A 15  C U 35  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog15  hydrog ? ? C A 15  N6 ? ? ? 1_555 C U 35  O4 ? ? C A 15  C U 35  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog16  hydrog ? ? C G 16  N1 ? ? ? 1_555 C C 34  N3 ? ? C G 16  C C 34  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog17  hydrog ? ? C G 16  N2 ? ? ? 1_555 C C 34  O2 ? ? C G 16  C C 34  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog18  hydrog ? ? C G 16  O6 ? ? ? 1_555 C C 34  N4 ? ? C G 16  C C 34  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog19  hydrog ? ? C A 17  N1 ? ? ? 1_555 C U 33  N3 ? ? C A 17  C U 33  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog20  hydrog ? ? C A 17  N6 ? ? ? 1_555 C U 33  O4 ? ? C A 17  C U 33  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog21  hydrog ? ? C C 18  N3 ? ? ? 1_555 C G 32  N1 ? ? C C 18  C G 32  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog22  hydrog ? ? C C 18  N4 ? ? ? 1_555 C G 32  O6 ? ? C C 18  C G 32  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog23  hydrog ? ? C C 18  O2 ? ? ? 1_555 C G 32  N2 ? ? C C 18  C G 32  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog24  hydrog ? ? C C 19  N3 ? ? ? 1_555 C G 30  N1 ? ? C C 19  C G 30  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog25  hydrog ? ? C C 19  N4 ? ? ? 1_555 C G 30  O6 ? ? C C 19  C G 30  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog26  hydrog ? ? C C 19  O2 ? ? ? 1_555 C G 30  N2 ? ? C C 19  C G 30  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog27  hydrog ? ? C U 20  N3 ? ? ? 1_555 C A 29  N1 ? ? C U 20  C A 29  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog28  hydrog ? ? C U 20  O4 ? ? ? 1_555 C A 29  N6 ? ? C U 20  C A 29  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog29  hydrog ? ? C C 21  N3 ? ? ? 1_555 C G 28  N1 ? ? C C 21  C G 28  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog30  hydrog ? ? C C 21  N4 ? ? ? 1_555 C G 28  O6 ? ? C C 21  C G 28  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog31  hydrog ? ? C C 21  O2 ? ? ? 1_555 C G 28  N2 ? ? C C 21  C G 28  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog32  hydrog ? ? C U 22  N3 ? ? ? 1_555 C A 27  N1 ? ? C U 22  C A 27  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog33  hydrog ? ? C U 22  O4 ? ? ? 1_555 C A 27  N6 ? ? C U 22  C A 27  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog34  hydrog ? ? C G 37  N1 ? ? ? 1_555 C C 128 N3 ? ? C G 37  C C 128 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog35  hydrog ? ? C G 37  N2 ? ? ? 1_555 C C 128 O2 ? ? C G 37  C C 128 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog36  hydrog ? ? C G 37  O6 ? ? ? 1_555 C C 128 N4 ? ? C G 37  C C 128 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog37  hydrog ? ? C G 38  N1 ? ? ? 1_555 C C 127 N3 ? ? C G 38  C C 127 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog38  hydrog ? ? C G 38  N2 ? ? ? 1_555 C C 127 O2 ? ? C G 38  C C 127 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog39  hydrog ? ? C G 38  O6 ? ? ? 1_555 C C 127 N4 ? ? C G 38  C C 127 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog40  hydrog ? ? C G 38  N1 ? ? ? 1_555 C C 128 N3 ? ? C G 38  C C 128 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog41  hydrog ? ? C G 38  N2 ? ? ? 1_555 C C 128 O2 ? ? C G 38  C C 128 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog42  hydrog ? ? C G 38  O6 ? ? ? 1_555 C C 128 N4 ? ? C G 38  C C 128 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog43  hydrog ? ? C U 39  N3 ? ? ? 1_555 C A 126 N1 ? ? C U 39  C A 126 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog44  hydrog ? ? C U 39  O4 ? ? ? 1_555 C A 126 N6 ? ? C U 39  C A 126 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog45  hydrog ? ? C C 42  N3 ? ? ? 1_555 C G 123 N1 ? ? C C 42  C G 123 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog46  hydrog ? ? C C 42  N4 ? ? ? 1_555 C G 123 O6 ? ? C C 42  C G 123 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog47  hydrog ? ? C C 42  O2 ? ? ? 1_555 C G 123 N2 ? ? C C 42  C G 123 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog48  hydrog ? ? C U 43  O2 ? ? ? 1_555 C G 122 N2 ? ? C U 43  C G 122 1_555 ? ? ? ? ? ? 'U-G MISPAIR' ? ? ? 
hydrog49  hydrog ? ? C U 44  O4 ? ? ? 1_555 C A 118 N6 ? ? C U 44  C A 118 1_555 ? ? ? ? ? ? 'U-A PAIR'    ? ? ? 
hydrog50  hydrog ? ? C G 46  O6 ? ? ? 1_555 C C 65  N4 ? ? C G 46  C C 65  1_555 ? ? ? ? ? ? 'G-C PAIR'    ? ? ? 
hydrog51  hydrog ? ? C G 46  N1 ? ? ? 1_555 C U 66  O2 ? ? C G 46  C U 66  1_555 ? ? ? ? ? ? 'G-U MISPAIR' ? ? ? 
hydrog52  hydrog ? ? C A 47  N1 ? ? ? 1_555 C U 64  N3 ? ? C A 47  C U 64  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog53  hydrog ? ? C A 47  N6 ? ? ? 1_555 C U 64  O4 ? ? C A 47  C U 64  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog54  hydrog ? ? C G 48  N1 ? ? ? 1_555 C C 63  O2 ? ? C G 48  C C 63  1_555 ? ? ? ? ? ? 'G-C PAIR'    ? ? ? 
hydrog55  hydrog ? ? C G 48  N2 ? ? ? 1_555 C U 64  O2 ? ? C G 48  C U 64  1_555 ? ? ? ? ? ? 'G-U MISPAIR' ? ? ? 
hydrog56  hydrog ? ? C A 49  N6 ? ? ? 1_555 C U 62  O4 ? ? C A 49  C U 62  1_555 ? ? ? ? ? ? 'A-U PAIR'    ? ? ? 
hydrog57  hydrog ? ? C A 49  N6 ? ? ? 1_555 C C 63  O2 ? ? C A 49  C C 63  1_555 ? ? ? ? ? ? 'A-C MISPAIR' ? ? ? 
hydrog58  hydrog ? ? C G 50  N1 ? ? ? 1_555 C C 61  N3 ? ? C G 50  C C 61  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog59  hydrog ? ? C G 50  N2 ? ? ? 1_555 C C 61  O2 ? ? C G 50  C C 61  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog60  hydrog ? ? C G 50  O6 ? ? ? 1_555 C C 61  N4 ? ? C G 50  C C 61  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog61  hydrog ? ? C U 51  N3 ? ? ? 1_555 C G 60  O6 ? ? C U 51  C G 60  1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog62  hydrog ? ? C U 51  O2 ? ? ? 1_555 C G 60  N1 ? ? C U 51  C G 60  1_555 ? ? ? ? ? ? TYPE_28_PAIR  ? ? ? 
hydrog63  hydrog ? ? C U 52  N3 ? ? ? 1_555 C A 161 N7 ? ? C U 52  C A 161 1_555 ? ? ? ? ? ? HOOGSTEEN     ? ? ? 
hydrog64  hydrog ? ? C U 52  O4 ? ? ? 1_555 C A 161 N6 ? ? C U 52  C A 161 1_555 ? ? ? ? ? ? HOOGSTEEN     ? ? ? 
hydrog65  hydrog ? ? C C 54  N3 ? ? ? 1_555 C G 165 N1 ? ? C C 54  C G 165 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog66  hydrog ? ? C C 54  N4 ? ? ? 1_555 C G 165 O6 ? ? C C 54  C G 165 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog67  hydrog ? ? C C 54  O2 ? ? ? 1_555 C G 165 N2 ? ? C C 54  C G 165 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog68  hydrog ? ? C U 55  N3 ? ? ? 1_555 C A 164 N1 ? ? C U 55  C A 164 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog69  hydrog ? ? C U 55  O4 ? ? ? 1_555 C A 164 N6 ? ? C U 55  C A 164 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog70  hydrog ? ? C C 56  N3 ? ? ? 1_555 C G 163 N1 ? ? C C 56  C G 163 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog71  hydrog ? ? C C 56  N4 ? ? ? 1_555 C G 163 O6 ? ? C C 56  C G 163 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog72  hydrog ? ? C C 56  O2 ? ? ? 1_555 C G 163 N2 ? ? C C 56  C G 163 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog73  hydrog ? ? C U 57  N3 ? ? ? 1_555 C A 162 N1 ? ? C U 57  C A 162 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog74  hydrog ? ? C U 57  O4 ? ? ? 1_555 C A 162 N6 ? ? C U 57  C A 162 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog75  hydrog ? ? C U 58  N3 ? ? ? 1_555 C A 161 N1 ? ? C U 58  C A 161 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog76  hydrog ? ? C U 58  O4 ? ? ? 1_555 C A 161 N6 ? ? C U 58  C A 161 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog77  hydrog ? ? C U 59  N3 ? ? ? 1_555 C A 160 N1 ? ? C U 59  C A 160 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog78  hydrog ? ? C U 59  O4 ? ? ? 1_555 C A 160 N6 ? ? C U 59  C A 160 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog79  hydrog ? ? C A 72  N1 ? ? ? 1_555 C G 89  N2 ? ? C A 72  C G 89  1_555 ? ? ? ? ? ? 'A-G MISPAIR' ? ? ? 
hydrog80  hydrog ? ? C A 72  N7 ? ? ? 1_555 C G 124 N2 ? ? C A 72  C G 124 1_555 ? ? ? ? ? ? 'A-G MISPAIR' ? ? ? 
hydrog81  hydrog ? ? C G 73  N2 ? ? ? 1_555 C C 88  O2 ? ? C G 73  C C 88  1_555 ? ? ? ? ? ? 'G-C PAIR'    ? ? ? 
hydrog82  hydrog ? ? C A 74  N1 ? ? ? 1_555 C U 87  N3 ? ? C A 74  C U 87  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog83  hydrog ? ? C A 74  N6 ? ? ? 1_555 C U 87  O4 ? ? C A 74  C U 87  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog84  hydrog ? ? C A 75  N1 ? ? ? 1_555 C U 86  N3 ? ? C A 75  C U 86  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog85  hydrog ? ? C A 75  N6 ? ? ? 1_555 C U 86  O4 ? ? C A 75  C U 86  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog86  hydrog ? ? C C 76  N3 ? ? ? 1_555 C G 85  N1 ? ? C C 76  C G 85  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog87  hydrog ? ? C C 76  N4 ? ? ? 1_555 C G 85  O6 ? ? C C 76  C G 85  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog88  hydrog ? ? C C 76  O2 ? ? ? 1_555 C G 85  N2 ? ? C C 76  C G 85  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog89  hydrog ? ? C C 77  N3 ? ? ? 1_555 C G 84  N1 ? ? C C 77  C G 84  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog90  hydrog ? ? C C 77  N4 ? ? ? 1_555 C G 84  O6 ? ? C C 77  C G 84  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog91  hydrog ? ? C C 77  O2 ? ? ? 1_555 C G 84  N2 ? ? C C 77  C G 84  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog92  hydrog ? ? C C 78  N3 ? ? ? 1_555 C G 83  N1 ? ? C C 78  C G 83  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog93  hydrog ? ? C C 78  N4 ? ? ? 1_555 C G 83  O6 ? ? C C 78  C G 83  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog94  hydrog ? ? C C 78  O2 ? ? ? 1_555 C G 83  N2 ? ? C C 78  C G 83  1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog95  hydrog ? ? C G 91  N7 ? ? ? 1_555 C A 117 N6 ? ? C G 91  C A 117 1_555 ? ? ? ? ? ? 'G-A MISPAIR' ? ? ? 
hydrog96  hydrog ? ? C G 91  N1 ? ? ? 1_555 C C 121 N3 ? ? C G 91  C C 121 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog97  hydrog ? ? C G 91  N2 ? ? ? 1_555 C C 121 O2 ? ? C G 91  C C 121 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog98  hydrog ? ? C G 91  O6 ? ? ? 1_555 C C 121 N4 ? ? C G 91  C C 121 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog99  hydrog ? ? C C 92  N3 ? ? ? 1_555 C G 120 N1 ? ? C C 92  C G 120 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog100 hydrog ? ? C C 92  N4 ? ? ? 1_555 C G 120 O6 ? ? C C 92  C G 120 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog101 hydrog ? ? C C 92  O2 ? ? ? 1_555 C G 120 N2 ? ? C C 92  C G 120 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog102 hydrog ? ? C A 93  N1 ? ? ? 1_555 C U 119 N3 ? ? C A 93  C U 119 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog103 hydrog ? ? C A 93  N6 ? ? ? 1_555 C U 119 O4 ? ? C A 93  C U 119 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog104 hydrog ? ? C U 94  N3 ? ? ? 1_555 C A 118 N1 ? ? C U 94  C A 118 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog105 hydrog ? ? C U 94  O4 ? ? ? 1_555 C A 118 N6 ? ? C U 94  C A 118 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog106 hydrog ? ? C G 96  N1 ? ? ? 1_555 C C 112 N3 ? ? C G 96  C C 112 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog107 hydrog ? ? C G 96  N2 ? ? ? 1_555 C C 112 O2 ? ? C G 96  C C 112 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog108 hydrog ? ? C G 96  O6 ? ? ? 1_555 C C 112 N4 ? ? C G 96  C C 112 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog109 hydrog ? ? C G 97  N1 ? ? ? 1_555 C C 112 N3 ? ? C G 97  C C 112 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog110 hydrog ? ? C G 97  N2 ? ? ? 1_555 C C 112 O2 ? ? C G 97  C C 112 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog111 hydrog ? ? C G 97  O6 ? ? ? 1_555 C C 112 N4 ? ? C G 97  C C 112 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog112 hydrog ? ? C C 98  N3 ? ? ? 1_555 C G 110 N1 ? ? C C 98  C G 110 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog113 hydrog ? ? C C 98  N4 ? ? ? 1_555 C G 110 O6 ? ? C C 98  C G 110 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog114 hydrog ? ? C C 98  O2 ? ? ? 1_555 C G 110 N2 ? ? C C 98  C G 110 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog115 hydrog ? ? C U 99  N3 ? ? ? 1_555 C A 109 N1 ? ? C U 99  C A 109 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog116 hydrog ? ? C U 99  O4 ? ? ? 1_555 C A 109 N6 ? ? C U 99  C A 109 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog117 hydrog ? ? C U 100 N3 ? ? ? 1_555 C A 108 N1 ? ? C U 100 C A 108 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog118 hydrog ? ? C U 100 O4 ? ? ? 1_555 C A 108 N6 ? ? C U 100 C A 108 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog119 hydrog ? ? C G 101 N1 ? ? ? 1_555 C C 107 N3 ? ? C G 101 C C 107 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog120 hydrog ? ? C G 101 N2 ? ? ? 1_555 C C 107 O2 ? ? C G 101 C C 107 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog121 hydrog ? ? C G 101 O6 ? ? ? 1_555 C C 107 N4 ? ? C G 101 C C 107 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog122 hydrog ? ? C U 130 N3 ? ? ? 1_555 C A 151 N1 ? ? C U 130 C A 151 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog123 hydrog ? ? C U 130 O4 ? ? ? 1_555 C A 151 N6 ? ? C U 130 C A 151 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog124 hydrog ? ? C A 131 N1 ? ? ? 1_555 C U 150 N3 ? ? C A 131 C U 150 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog125 hydrog ? ? C A 131 N6 ? ? ? 1_555 C U 150 O4 ? ? C A 131 C U 150 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog126 hydrog ? ? C C 132 N3 ? ? ? 1_555 C G 149 N1 ? ? C C 132 C G 149 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog127 hydrog ? ? C C 132 N4 ? ? ? 1_555 C G 149 O6 ? ? C C 132 C G 149 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog128 hydrog ? ? C C 132 O2 ? ? ? 1_555 C G 149 N2 ? ? C C 132 C G 149 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog129 hydrog ? ? C A 133 N1 ? ? ? 1_555 C U 148 N3 ? ? C A 133 C U 148 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog130 hydrog ? ? C A 133 N6 ? ? ? 1_555 C U 148 O4 ? ? C A 133 C U 148 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog131 hydrog ? ? C G 134 N1 ? ? ? 1_555 C C 147 N3 ? ? C G 134 C C 147 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog132 hydrog ? ? C G 134 N2 ? ? ? 1_555 C C 147 O2 ? ? C G 134 C C 147 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog133 hydrog ? ? C G 134 O6 ? ? ? 1_555 C C 147 N4 ? ? C G 134 C C 147 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog134 hydrog ? ? C U 135 N3 ? ? ? 1_555 C A 146 N1 ? ? C U 135 C A 146 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog135 hydrog ? ? C U 135 O4 ? ? ? 1_555 C A 146 N6 ? ? C U 135 C A 146 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog136 hydrog ? ? C G 136 N1 ? ? ? 1_555 C C 145 N3 ? ? C G 136 C C 145 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog137 hydrog ? ? C G 136 N2 ? ? ? 1_555 C C 145 O2 ? ? C G 136 C C 145 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog138 hydrog ? ? C G 136 O6 ? ? ? 1_555 C C 145 N4 ? ? C G 136 C C 145 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog139 hydrog ? ? C U 137 N3 ? ? ? 1_555 C A 144 N1 ? ? C U 137 C A 144 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog140 hydrog ? ? C U 137 O4 ? ? ? 1_555 C A 144 N6 ? ? C U 137 C A 144 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog141 hydrog ? ? C U 137 N3 ? ? ? 1_555 C C 145 N3 ? ? C U 137 C C 145 1_555 ? ? ? ? ? ? TYPE_18_PAIR  ? ? ? 
hydrog142 hydrog ? ? C U 137 O4 ? ? ? 1_555 C C 145 N4 ? ? C U 137 C C 145 1_555 ? ? ? ? ? ? TYPE_18_PAIR  ? ? ? 
hydrog143 hydrog ? ? C U 138 N3 ? ? ? 1_555 C A 143 N1 ? ? C U 138 C A 143 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog144 hydrog ? ? C U 138 O4 ? ? ? 1_555 C A 143 N6 ? ? C U 138 C A 143 1_555 ? ? ? ? ? ? WATSON-CRICK  ? ? ? 
hydrog145 hydrog ? ? C G 139 N2 ? ? ? 1_555 C A 142 N7 ? ? C G 139 C A 142 1_555 ? ? ? ? ? ? TYPE_11_PAIR  ? ? ? 
hydrog146 hydrog ? ? C G 139 N3 ? ? ? 1_555 C A 142 N6 ? ? C G 139 C A 142 1_555 ? ? ? ? ? ? TYPE_11_PAIR  ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 44  ? CYS A 45  ? GLU A 44  CYS A 45  
AA1 2 ILE A 237 ? SER A 240 ? ILE A 237 SER A 240 
AA1 3 ILE A 209 ? GLN A 211 ? ILE A 209 GLN A 211 
AA1 4 VAL A 62  ? PHE A 67  ? VAL A 62  PHE A 67  
AA1 5 ARG A 94  ? ILE A 99  ? ARG A 94  ILE A 99  
AA1 6 VAL A 140 ? TRP A 144 ? VAL A 140 TRP A 144 
AA2 1 PHE A 306 ? VAL A 308 ? PHE A 306 VAL A 308 
AA2 2 LYS A 318 ? PHE A 320 ? LYS A 318 PHE A 320 
AA3 1 GLU B 44  ? ILE B 46  ? GLU B 44  ILE B 46  
AA3 2 ILE B 237 ? SER B 240 ? ILE B 237 SER B 240 
AA3 3 ILE B 209 ? CYS B 210 ? ILE B 209 CYS B 210 
AA4 1 TYR B 64  ? PHE B 67  ? TYR B 64  PHE B 67  
AA4 2 VAL B 95  ? ILE B 99  ? VAL B 95  ILE B 99  
AA4 3 VAL B 140 ? TRP B 144 ? VAL B 140 TRP B 144 
AA5 1 PHE B 306 ? VAL B 308 ? PHE B 306 VAL B 308 
AA5 2 LYS B 318 ? PHE B 320 ? LYS B 318 PHE B 320 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU A 44  ? N GLU A 44  O SER A 240 ? O SER A 240 
AA1 2 3 O ILE A 237 ? O ILE A 237 N CYS A 210 ? N CYS A 210 
AA1 3 4 N ILE A 209 ? N ILE A 209 O VAL A 62  ? O VAL A 62  
AA1 4 5 N CYS A 63  ? N CYS A 63  O LYS A 96  ? O LYS A 96  
AA1 5 6 N ILE A 97  ? N ILE A 97  O GLU A 141 ? O GLU A 141 
AA2 1 2 N PHE A 306 ? N PHE A 306 O PHE A 320 ? O PHE A 320 
AA3 1 2 N GLU B 44  ? N GLU B 44  O SER B 240 ? O SER B 240 
AA3 2 3 O LEU B 239 ? O LEU B 239 N CYS B 210 ? N CYS B 210 
AA4 1 2 N ASP B 65  ? N ASP B 65  O TRP B 98  ? O TRP B 98  
AA4 2 3 N ILE B 99  ? N ILE B 99  O LEU B 143 ? O LEU B 143 
AA5 1 2 N VAL B 308 ? N VAL B 308 O LYS B 318 ? O LYS B 318 
# 
_pdbx_entry_details.entry_id                   8ZMI 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   B LYS 277 ? ? "O2'" C U   23  ? ? 2.15 
2 1 OD1 B ASP 101 ? ? OG    B SER 145 ? ? 2.18 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 "O3'" C U 23  ? ? P  C A 24  ? ? OP1 C A 24  ? ? 117.46 110.50 6.96  1.10 Y 
2 1 N1    C C 112 ? ? C2 C C 112 ? ? O2  C C 112 ? ? 122.56 118.90 3.66  0.60 N 
3 1 N3    C C 112 ? ? C2 C C 112 ? ? O2  C C 112 ? ? 116.70 121.90 -5.20 0.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 60  ? ? -153.52 80.11   
2  1 ALA A 100 ? ? -93.22  55.06   
3  1 ASN A 108 ? ? 77.13   -9.11   
4  1 MET A 110 ? ? 60.47   61.90   
5  1 ASN A 234 ? ? 70.69   73.08   
6  1 ASN B 108 ? ? 65.20   60.98   
7  1 SER B 182 ? ? 178.64  -123.96 
8  1 ALA B 189 ? ? -26.32  -37.85  
9  1 PRO B 259 ? ? -77.77  43.72   
10 1 LEU B 298 ? ? -121.15 -51.56  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZMI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8ZMI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.49 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               325881 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Cryo-EM structure of BMV TLS-TyrRS-ATP(Pre-1a state)' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8ZMI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1300 
_em_imaging.nominal_defocus_max             3300 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8ZMI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZMI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8ZMI 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1  ? A MET 1  
2  1 Y 1 A GLU 2  ? A GLU 2  
3  1 Y 1 A GLN 3  ? A GLN 3  
4  1 Y 1 A ALA 4  ? A ALA 4  
5  1 Y 1 A PRO 5  ? A PRO 5  
6  1 Y 1 A SER 6  ? A SER 6  
7  1 Y 1 A GLU 7  ? A GLU 7  
8  1 Y 1 A ALA 8  ? A ALA 8  
9  1 Y 1 A LEU 9  ? A LEU 9  
10 1 Y 1 A GLN 10 ? A GLN 10 
11 1 Y 1 A SER 11 ? A SER 11 
12 1 Y 1 A LEU 12 ? A LEU 12 
13 1 Y 1 A SER 13 ? A SER 13 
14 1 Y 1 A VAL 14 ? A VAL 14 
15 1 Y 1 A SER 15 ? A SER 15 
16 1 Y 1 A ASP 16 ? A ASP 16 
17 1 Y 1 A SER 17 ? A SER 17 
18 1 Y 1 A GLN 18 ? A GLN 18 
19 1 Y 1 A ILE 19 ? A ILE 19 
20 1 Y 1 A PRO 20 ? A PRO 20 
21 1 Y 1 A GLN 21 ? A GLN 21 
22 1 Y 1 A SER 22 ? A SER 22 
23 1 Y 1 A SER 23 ? A SER 23 
24 1 Y 1 A ASN 24 ? A ASN 24 
25 1 Y 1 A SER 25 ? A SER 25 
26 1 Y 1 A THR 26 ? A THR 26 
27 1 Y 1 A PRO 27 ? A PRO 27 
28 1 Y 1 A GLN 28 ? A GLN 28 
29 1 Y 1 A LEU 29 ? A LEU 29 
30 1 Y 1 A SER 30 ? A SER 30 
31 1 Y 1 B MET 1  ? B MET 1  
32 1 Y 1 B GLU 2  ? B GLU 2  
33 1 Y 1 B GLN 3  ? B GLN 3  
34 1 Y 1 B ALA 4  ? B ALA 4  
35 1 Y 1 B PRO 5  ? B PRO 5  
36 1 Y 1 B SER 6  ? B SER 6  
37 1 Y 1 B GLU 7  ? B GLU 7  
38 1 Y 1 B ALA 8  ? B ALA 8  
39 1 Y 1 B LEU 9  ? B LEU 9  
40 1 Y 1 B GLN 10 ? B GLN 10 
41 1 Y 1 B SER 11 ? B SER 11 
42 1 Y 1 B LEU 12 ? B LEU 12 
43 1 Y 1 B SER 13 ? B SER 13 
44 1 Y 1 B VAL 14 ? B VAL 14 
45 1 Y 1 B SER 15 ? B SER 15 
46 1 Y 1 B ASP 16 ? B ASP 16 
47 1 Y 1 B SER 17 ? B SER 17 
48 1 Y 1 B GLN 18 ? B GLN 18 
49 1 Y 1 B ILE 19 ? B ILE 19 
50 1 Y 1 B PRO 20 ? B PRO 20 
51 1 Y 1 B GLN 21 ? B GLN 21 
52 1 Y 1 B SER 22 ? B SER 22 
53 1 Y 1 B SER 23 ? B SER 23 
54 1 Y 1 B ASN 24 ? B ASN 24 
55 1 Y 1 B SER 25 ? B SER 25 
56 1 Y 1 B THR 26 ? B THR 26 
57 1 Y 1 B PRO 27 ? B PRO 27 
58 1 Y 1 B GLN 28 ? B GLN 28 
59 1 Y 1 B LEU 29 ? B LEU 29 
60 1 Y 1 B SER 30 ? B SER 30 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O N N 1   
A   P      P N N 2   
A   OP1    O N N 3   
A   OP2    O N N 4   
A   "O5'"  O N N 5   
A   "C5'"  C N N 6   
A   "C4'"  C N R 7   
A   "O4'"  O N N 8   
A   "C3'"  C N S 9   
A   "O3'"  O N N 10  
A   "C2'"  C N R 11  
A   "O2'"  O N N 12  
A   "C1'"  C N R 13  
A   N9     N Y N 14  
A   C8     C Y N 15  
A   N7     N Y N 16  
A   C5     C Y N 17  
A   C6     C Y N 18  
A   N6     N N N 19  
A   N1     N Y N 20  
A   C2     C Y N 21  
A   N3     N Y N 22  
A   C4     C Y N 23  
A   HOP3   H N N 24  
A   HOP2   H N N 25  
A   "H5'"  H N N 26  
A   "H5''" H N N 27  
A   "H4'"  H N N 28  
A   "H3'"  H N N 29  
A   "HO3'" H N N 30  
A   "H2'"  H N N 31  
A   "HO2'" H N N 32  
A   "H1'"  H N N 33  
A   H8     H N N 34  
A   H61    H N N 35  
A   H62    H N N 36  
A   H2     H N N 37  
ALA N      N N N 38  
ALA CA     C N S 39  
ALA C      C N N 40  
ALA O      O N N 41  
ALA CB     C N N 42  
ALA OXT    O N N 43  
ALA H      H N N 44  
ALA H2     H N N 45  
ALA HA     H N N 46  
ALA HB1    H N N 47  
ALA HB2    H N N 48  
ALA HB3    H N N 49  
ALA HXT    H N N 50  
ARG N      N N N 51  
ARG CA     C N S 52  
ARG C      C N N 53  
ARG O      O N N 54  
ARG CB     C N N 55  
ARG CG     C N N 56  
ARG CD     C N N 57  
ARG NE     N N N 58  
ARG CZ     C N N 59  
ARG NH1    N N N 60  
ARG NH2    N N N 61  
ARG OXT    O N N 62  
ARG H      H N N 63  
ARG H2     H N N 64  
ARG HA     H N N 65  
ARG HB2    H N N 66  
ARG HB3    H N N 67  
ARG HG2    H N N 68  
ARG HG3    H N N 69  
ARG HD2    H N N 70  
ARG HD3    H N N 71  
ARG HE     H N N 72  
ARG HH11   H N N 73  
ARG HH12   H N N 74  
ARG HH21   H N N 75  
ARG HH22   H N N 76  
ARG HXT    H N N 77  
ASN N      N N N 78  
ASN CA     C N S 79  
ASN C      C N N 80  
ASN O      O N N 81  
ASN CB     C N N 82  
ASN CG     C N N 83  
ASN OD1    O N N 84  
ASN ND2    N N N 85  
ASN OXT    O N N 86  
ASN H      H N N 87  
ASN H2     H N N 88  
ASN HA     H N N 89  
ASN HB2    H N N 90  
ASN HB3    H N N 91  
ASN HD21   H N N 92  
ASN HD22   H N N 93  
ASN HXT    H N N 94  
ASP N      N N N 95  
ASP CA     C N S 96  
ASP C      C N N 97  
ASP O      O N N 98  
ASP CB     C N N 99  
ASP CG     C N N 100 
ASP OD1    O N N 101 
ASP OD2    O N N 102 
ASP OXT    O N N 103 
ASP H      H N N 104 
ASP H2     H N N 105 
ASP HA     H N N 106 
ASP HB2    H N N 107 
ASP HB3    H N N 108 
ASP HD2    H N N 109 
ASP HXT    H N N 110 
ATP PG     P N N 111 
ATP O1G    O N N 112 
ATP O2G    O N N 113 
ATP O3G    O N N 114 
ATP PB     P N R 115 
ATP O1B    O N N 116 
ATP O2B    O N N 117 
ATP O3B    O N N 118 
ATP PA     P N R 119 
ATP O1A    O N N 120 
ATP O2A    O N N 121 
ATP O3A    O N N 122 
ATP "O5'"  O N N 123 
ATP "C5'"  C N N 124 
ATP "C4'"  C N R 125 
ATP "O4'"  O N N 126 
ATP "C3'"  C N S 127 
ATP "O3'"  O N N 128 
ATP "C2'"  C N R 129 
ATP "O2'"  O N N 130 
ATP "C1'"  C N R 131 
ATP N9     N Y N 132 
ATP C8     C Y N 133 
ATP N7     N Y N 134 
ATP C5     C Y N 135 
ATP C6     C Y N 136 
ATP N6     N N N 137 
ATP N1     N Y N 138 
ATP C2     C Y N 139 
ATP N3     N Y N 140 
ATP C4     C Y N 141 
ATP HOG2   H N N 142 
ATP HOG3   H N N 143 
ATP HOB2   H N N 144 
ATP HOA2   H N N 145 
ATP "H5'1" H N N 146 
ATP "H5'2" H N N 147 
ATP "H4'"  H N N 148 
ATP "H3'"  H N N 149 
ATP "HO3'" H N N 150 
ATP "H2'"  H N N 151 
ATP "HO2'" H N N 152 
ATP "H1'"  H N N 153 
ATP H8     H N N 154 
ATP HN61   H N N 155 
ATP HN62   H N N 156 
ATP H2     H N N 157 
C   OP3    O N N 158 
C   P      P N N 159 
C   OP1    O N N 160 
C   OP2    O N N 161 
C   "O5'"  O N N 162 
C   "C5'"  C N N 163 
C   "C4'"  C N R 164 
C   "O4'"  O N N 165 
C   "C3'"  C N S 166 
C   "O3'"  O N N 167 
C   "C2'"  C N R 168 
C   "O2'"  O N N 169 
C   "C1'"  C N R 170 
C   N1     N N N 171 
C   C2     C N N 172 
C   O2     O N N 173 
C   N3     N N N 174 
C   C4     C N N 175 
C   N4     N N N 176 
C   C5     C N N 177 
C   C6     C N N 178 
C   HOP3   H N N 179 
C   HOP2   H N N 180 
C   "H5'"  H N N 181 
C   "H5''" H N N 182 
C   "H4'"  H N N 183 
C   "H3'"  H N N 184 
C   "HO3'" H N N 185 
C   "H2'"  H N N 186 
C   "HO2'" H N N 187 
C   "H1'"  H N N 188 
C   H41    H N N 189 
C   H42    H N N 190 
C   H5     H N N 191 
C   H6     H N N 192 
CYS N      N N N 193 
CYS CA     C N R 194 
CYS C      C N N 195 
CYS O      O N N 196 
CYS CB     C N N 197 
CYS SG     S N N 198 
CYS OXT    O N N 199 
CYS H      H N N 200 
CYS H2     H N N 201 
CYS HA     H N N 202 
CYS HB2    H N N 203 
CYS HB3    H N N 204 
CYS HG     H N N 205 
CYS HXT    H N N 206 
G   OP3    O N N 207 
G   P      P N N 208 
G   OP1    O N N 209 
G   OP2    O N N 210 
G   "O5'"  O N N 211 
G   "C5'"  C N N 212 
G   "C4'"  C N R 213 
G   "O4'"  O N N 214 
G   "C3'"  C N S 215 
G   "O3'"  O N N 216 
G   "C2'"  C N R 217 
G   "O2'"  O N N 218 
G   "C1'"  C N R 219 
G   N9     N Y N 220 
G   C8     C Y N 221 
G   N7     N Y N 222 
G   C5     C Y N 223 
G   C6     C N N 224 
G   O6     O N N 225 
G   N1     N N N 226 
G   C2     C N N 227 
G   N2     N N N 228 
G   N3     N N N 229 
G   C4     C Y N 230 
G   HOP3   H N N 231 
G   HOP2   H N N 232 
G   "H5'"  H N N 233 
G   "H5''" H N N 234 
G   "H4'"  H N N 235 
G   "H3'"  H N N 236 
G   "HO3'" H N N 237 
G   "H2'"  H N N 238 
G   "HO2'" H N N 239 
G   "H1'"  H N N 240 
G   H8     H N N 241 
G   H1     H N N 242 
G   H21    H N N 243 
G   H22    H N N 244 
GLN N      N N N 245 
GLN CA     C N S 246 
GLN C      C N N 247 
GLN O      O N N 248 
GLN CB     C N N 249 
GLN CG     C N N 250 
GLN CD     C N N 251 
GLN OE1    O N N 252 
GLN NE2    N N N 253 
GLN OXT    O N N 254 
GLN H      H N N 255 
GLN H2     H N N 256 
GLN HA     H N N 257 
GLN HB2    H N N 258 
GLN HB3    H N N 259 
GLN HG2    H N N 260 
GLN HG3    H N N 261 
GLN HE21   H N N 262 
GLN HE22   H N N 263 
GLN HXT    H N N 264 
GLU N      N N N 265 
GLU CA     C N S 266 
GLU C      C N N 267 
GLU O      O N N 268 
GLU CB     C N N 269 
GLU CG     C N N 270 
GLU CD     C N N 271 
GLU OE1    O N N 272 
GLU OE2    O N N 273 
GLU OXT    O N N 274 
GLU H      H N N 275 
GLU H2     H N N 276 
GLU HA     H N N 277 
GLU HB2    H N N 278 
GLU HB3    H N N 279 
GLU HG2    H N N 280 
GLU HG3    H N N 281 
GLU HE2    H N N 282 
GLU HXT    H N N 283 
GLY N      N N N 284 
GLY CA     C N N 285 
GLY C      C N N 286 
GLY O      O N N 287 
GLY OXT    O N N 288 
GLY H      H N N 289 
GLY H2     H N N 290 
GLY HA2    H N N 291 
GLY HA3    H N N 292 
GLY HXT    H N N 293 
HIS N      N N N 294 
HIS CA     C N S 295 
HIS C      C N N 296 
HIS O      O N N 297 
HIS CB     C N N 298 
HIS CG     C Y N 299 
HIS ND1    N Y N 300 
HIS CD2    C Y N 301 
HIS CE1    C Y N 302 
HIS NE2    N Y N 303 
HIS OXT    O N N 304 
HIS H      H N N 305 
HIS H2     H N N 306 
HIS HA     H N N 307 
HIS HB2    H N N 308 
HIS HB3    H N N 309 
HIS HD1    H N N 310 
HIS HD2    H N N 311 
HIS HE1    H N N 312 
HIS HE2    H N N 313 
HIS HXT    H N N 314 
ILE N      N N N 315 
ILE CA     C N S 316 
ILE C      C N N 317 
ILE O      O N N 318 
ILE CB     C N S 319 
ILE CG1    C N N 320 
ILE CG2    C N N 321 
ILE CD1    C N N 322 
ILE OXT    O N N 323 
ILE H      H N N 324 
ILE H2     H N N 325 
ILE HA     H N N 326 
ILE HB     H N N 327 
ILE HG12   H N N 328 
ILE HG13   H N N 329 
ILE HG21   H N N 330 
ILE HG22   H N N 331 
ILE HG23   H N N 332 
ILE HD11   H N N 333 
ILE HD12   H N N 334 
ILE HD13   H N N 335 
ILE HXT    H N N 336 
LEU N      N N N 337 
LEU CA     C N S 338 
LEU C      C N N 339 
LEU O      O N N 340 
LEU CB     C N N 341 
LEU CG     C N N 342 
LEU CD1    C N N 343 
LEU CD2    C N N 344 
LEU OXT    O N N 345 
LEU H      H N N 346 
LEU H2     H N N 347 
LEU HA     H N N 348 
LEU HB2    H N N 349 
LEU HB3    H N N 350 
LEU HG     H N N 351 
LEU HD11   H N N 352 
LEU HD12   H N N 353 
LEU HD13   H N N 354 
LEU HD21   H N N 355 
LEU HD22   H N N 356 
LEU HD23   H N N 357 
LEU HXT    H N N 358 
LYS N      N N N 359 
LYS CA     C N S 360 
LYS C      C N N 361 
LYS O      O N N 362 
LYS CB     C N N 363 
LYS CG     C N N 364 
LYS CD     C N N 365 
LYS CE     C N N 366 
LYS NZ     N N N 367 
LYS OXT    O N N 368 
LYS H      H N N 369 
LYS H2     H N N 370 
LYS HA     H N N 371 
LYS HB2    H N N 372 
LYS HB3    H N N 373 
LYS HG2    H N N 374 
LYS HG3    H N N 375 
LYS HD2    H N N 376 
LYS HD3    H N N 377 
LYS HE2    H N N 378 
LYS HE3    H N N 379 
LYS HZ1    H N N 380 
LYS HZ2    H N N 381 
LYS HZ3    H N N 382 
LYS HXT    H N N 383 
MET N      N N N 384 
MET CA     C N S 385 
MET C      C N N 386 
MET O      O N N 387 
MET CB     C N N 388 
MET CG     C N N 389 
MET SD     S N N 390 
MET CE     C N N 391 
MET OXT    O N N 392 
MET H      H N N 393 
MET H2     H N N 394 
MET HA     H N N 395 
MET HB2    H N N 396 
MET HB3    H N N 397 
MET HG2    H N N 398 
MET HG3    H N N 399 
MET HE1    H N N 400 
MET HE2    H N N 401 
MET HE3    H N N 402 
MET HXT    H N N 403 
PHE N      N N N 404 
PHE CA     C N S 405 
PHE C      C N N 406 
PHE O      O N N 407 
PHE CB     C N N 408 
PHE CG     C Y N 409 
PHE CD1    C Y N 410 
PHE CD2    C Y N 411 
PHE CE1    C Y N 412 
PHE CE2    C Y N 413 
PHE CZ     C Y N 414 
PHE OXT    O N N 415 
PHE H      H N N 416 
PHE H2     H N N 417 
PHE HA     H N N 418 
PHE HB2    H N N 419 
PHE HB3    H N N 420 
PHE HD1    H N N 421 
PHE HD2    H N N 422 
PHE HE1    H N N 423 
PHE HE2    H N N 424 
PHE HZ     H N N 425 
PHE HXT    H N N 426 
PRO N      N N N 427 
PRO CA     C N S 428 
PRO C      C N N 429 
PRO O      O N N 430 
PRO CB     C N N 431 
PRO CG     C N N 432 
PRO CD     C N N 433 
PRO OXT    O N N 434 
PRO H      H N N 435 
PRO HA     H N N 436 
PRO HB2    H N N 437 
PRO HB3    H N N 438 
PRO HG2    H N N 439 
PRO HG3    H N N 440 
PRO HD2    H N N 441 
PRO HD3    H N N 442 
PRO HXT    H N N 443 
SER N      N N N 444 
SER CA     C N S 445 
SER C      C N N 446 
SER O      O N N 447 
SER CB     C N N 448 
SER OG     O N N 449 
SER OXT    O N N 450 
SER H      H N N 451 
SER H2     H N N 452 
SER HA     H N N 453 
SER HB2    H N N 454 
SER HB3    H N N 455 
SER HG     H N N 456 
SER HXT    H N N 457 
THR N      N N N 458 
THR CA     C N S 459 
THR C      C N N 460 
THR O      O N N 461 
THR CB     C N R 462 
THR OG1    O N N 463 
THR CG2    C N N 464 
THR OXT    O N N 465 
THR H      H N N 466 
THR H2     H N N 467 
THR HA     H N N 468 
THR HB     H N N 469 
THR HG1    H N N 470 
THR HG21   H N N 471 
THR HG22   H N N 472 
THR HG23   H N N 473 
THR HXT    H N N 474 
TRP N      N N N 475 
TRP CA     C N S 476 
TRP C      C N N 477 
TRP O      O N N 478 
TRP CB     C N N 479 
TRP CG     C Y N 480 
TRP CD1    C Y N 481 
TRP CD2    C Y N 482 
TRP NE1    N Y N 483 
TRP CE2    C Y N 484 
TRP CE3    C Y N 485 
TRP CZ2    C Y N 486 
TRP CZ3    C Y N 487 
TRP CH2    C Y N 488 
TRP OXT    O N N 489 
TRP H      H N N 490 
TRP H2     H N N 491 
TRP HA     H N N 492 
TRP HB2    H N N 493 
TRP HB3    H N N 494 
TRP HD1    H N N 495 
TRP HE1    H N N 496 
TRP HE3    H N N 497 
TRP HZ2    H N N 498 
TRP HZ3    H N N 499 
TRP HH2    H N N 500 
TRP HXT    H N N 501 
TYR N      N N N 502 
TYR CA     C N S 503 
TYR C      C N N 504 
TYR O      O N N 505 
TYR CB     C N N 506 
TYR CG     C Y N 507 
TYR CD1    C Y N 508 
TYR CD2    C Y N 509 
TYR CE1    C Y N 510 
TYR CE2    C Y N 511 
TYR CZ     C Y N 512 
TYR OH     O N N 513 
TYR OXT    O N N 514 
TYR H      H N N 515 
TYR H2     H N N 516 
TYR HA     H N N 517 
TYR HB2    H N N 518 
TYR HB3    H N N 519 
TYR HD1    H N N 520 
TYR HD2    H N N 521 
TYR HE1    H N N 522 
TYR HE2    H N N 523 
TYR HH     H N N 524 
TYR HXT    H N N 525 
U   OP3    O N N 526 
U   P      P N N 527 
U   OP1    O N N 528 
U   OP2    O N N 529 
U   "O5'"  O N N 530 
U   "C5'"  C N N 531 
U   "C4'"  C N R 532 
U   "O4'"  O N N 533 
U   "C3'"  C N S 534 
U   "O3'"  O N N 535 
U   "C2'"  C N R 536 
U   "O2'"  O N N 537 
U   "C1'"  C N R 538 
U   N1     N N N 539 
U   C2     C N N 540 
U   O2     O N N 541 
U   N3     N N N 542 
U   C4     C N N 543 
U   O4     O N N 544 
U   C5     C N N 545 
U   C6     C N N 546 
U   HOP3   H N N 547 
U   HOP2   H N N 548 
U   "H5'"  H N N 549 
U   "H5''" H N N 550 
U   "H4'"  H N N 551 
U   "H3'"  H N N 552 
U   "HO3'" H N N 553 
U   "H2'"  H N N 554 
U   "HO2'" H N N 555 
U   "H1'"  H N N 556 
U   H3     H N N 557 
U   H5     H N N 558 
U   H6     H N N 559 
VAL N      N N N 560 
VAL CA     C N S 561 
VAL C      C N N 562 
VAL O      O N N 563 
VAL CB     C N N 564 
VAL CG1    C N N 565 
VAL CG2    C N N 566 
VAL OXT    O N N 567 
VAL H      H N N 568 
VAL H2     H N N 569 
VAL HA     H N N 570 
VAL HB     H N N 571 
VAL HG11   H N N 572 
VAL HG12   H N N 573 
VAL HG13   H N N 574 
VAL HG21   H N N 575 
VAL HG22   H N N 576 
VAL HG23   H N N 577 
VAL HXT    H N N 578 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
ATP PG    O1G    doub N N 109 
ATP PG    O2G    sing N N 110 
ATP PG    O3G    sing N N 111 
ATP PG    O3B    sing N N 112 
ATP O2G   HOG2   sing N N 113 
ATP O3G   HOG3   sing N N 114 
ATP PB    O1B    doub N N 115 
ATP PB    O2B    sing N N 116 
ATP PB    O3B    sing N N 117 
ATP PB    O3A    sing N N 118 
ATP O2B   HOB2   sing N N 119 
ATP PA    O1A    doub N N 120 
ATP PA    O2A    sing N N 121 
ATP PA    O3A    sing N N 122 
ATP PA    "O5'"  sing N N 123 
ATP O2A   HOA2   sing N N 124 
ATP "O5'" "C5'"  sing N N 125 
ATP "C5'" "C4'"  sing N N 126 
ATP "C5'" "H5'1" sing N N 127 
ATP "C5'" "H5'2" sing N N 128 
ATP "C4'" "O4'"  sing N N 129 
ATP "C4'" "C3'"  sing N N 130 
ATP "C4'" "H4'"  sing N N 131 
ATP "O4'" "C1'"  sing N N 132 
ATP "C3'" "O3'"  sing N N 133 
ATP "C3'" "C2'"  sing N N 134 
ATP "C3'" "H3'"  sing N N 135 
ATP "O3'" "HO3'" sing N N 136 
ATP "C2'" "O2'"  sing N N 137 
ATP "C2'" "C1'"  sing N N 138 
ATP "C2'" "H2'"  sing N N 139 
ATP "O2'" "HO2'" sing N N 140 
ATP "C1'" N9     sing N N 141 
ATP "C1'" "H1'"  sing N N 142 
ATP N9    C8     sing Y N 143 
ATP N9    C4     sing Y N 144 
ATP C8    N7     doub Y N 145 
ATP C8    H8     sing N N 146 
ATP N7    C5     sing Y N 147 
ATP C5    C6     sing Y N 148 
ATP C5    C4     doub Y N 149 
ATP C6    N6     sing N N 150 
ATP C6    N1     doub Y N 151 
ATP N6    HN61   sing N N 152 
ATP N6    HN62   sing N N 153 
ATP N1    C2     sing Y N 154 
ATP C2    N3     doub Y N 155 
ATP C2    H2     sing N N 156 
ATP N3    C4     sing Y N 157 
C   OP3   P      sing N N 158 
C   OP3   HOP3   sing N N 159 
C   P     OP1    doub N N 160 
C   P     OP2    sing N N 161 
C   P     "O5'"  sing N N 162 
C   OP2   HOP2   sing N N 163 
C   "O5'" "C5'"  sing N N 164 
C   "C5'" "C4'"  sing N N 165 
C   "C5'" "H5'"  sing N N 166 
C   "C5'" "H5''" sing N N 167 
C   "C4'" "O4'"  sing N N 168 
C   "C4'" "C3'"  sing N N 169 
C   "C4'" "H4'"  sing N N 170 
C   "O4'" "C1'"  sing N N 171 
C   "C3'" "O3'"  sing N N 172 
C   "C3'" "C2'"  sing N N 173 
C   "C3'" "H3'"  sing N N 174 
C   "O3'" "HO3'" sing N N 175 
C   "C2'" "O2'"  sing N N 176 
C   "C2'" "C1'"  sing N N 177 
C   "C2'" "H2'"  sing N N 178 
C   "O2'" "HO2'" sing N N 179 
C   "C1'" N1     sing N N 180 
C   "C1'" "H1'"  sing N N 181 
C   N1    C2     sing N N 182 
C   N1    C6     sing N N 183 
C   C2    O2     doub N N 184 
C   C2    N3     sing N N 185 
C   N3    C4     doub N N 186 
C   C4    N4     sing N N 187 
C   C4    C5     sing N N 188 
C   N4    H41    sing N N 189 
C   N4    H42    sing N N 190 
C   C5    C6     doub N N 191 
C   C5    H5     sing N N 192 
C   C6    H6     sing N N 193 
CYS N     CA     sing N N 194 
CYS N     H      sing N N 195 
CYS N     H2     sing N N 196 
CYS CA    C      sing N N 197 
CYS CA    CB     sing N N 198 
CYS CA    HA     sing N N 199 
CYS C     O      doub N N 200 
CYS C     OXT    sing N N 201 
CYS CB    SG     sing N N 202 
CYS CB    HB2    sing N N 203 
CYS CB    HB3    sing N N 204 
CYS SG    HG     sing N N 205 
CYS OXT   HXT    sing N N 206 
G   OP3   P      sing N N 207 
G   OP3   HOP3   sing N N 208 
G   P     OP1    doub N N 209 
G   P     OP2    sing N N 210 
G   P     "O5'"  sing N N 211 
G   OP2   HOP2   sing N N 212 
G   "O5'" "C5'"  sing N N 213 
G   "C5'" "C4'"  sing N N 214 
G   "C5'" "H5'"  sing N N 215 
G   "C5'" "H5''" sing N N 216 
G   "C4'" "O4'"  sing N N 217 
G   "C4'" "C3'"  sing N N 218 
G   "C4'" "H4'"  sing N N 219 
G   "O4'" "C1'"  sing N N 220 
G   "C3'" "O3'"  sing N N 221 
G   "C3'" "C2'"  sing N N 222 
G   "C3'" "H3'"  sing N N 223 
G   "O3'" "HO3'" sing N N 224 
G   "C2'" "O2'"  sing N N 225 
G   "C2'" "C1'"  sing N N 226 
G   "C2'" "H2'"  sing N N 227 
G   "O2'" "HO2'" sing N N 228 
G   "C1'" N9     sing N N 229 
G   "C1'" "H1'"  sing N N 230 
G   N9    C8     sing Y N 231 
G   N9    C4     sing Y N 232 
G   C8    N7     doub Y N 233 
G   C8    H8     sing N N 234 
G   N7    C5     sing Y N 235 
G   C5    C6     sing N N 236 
G   C5    C4     doub Y N 237 
G   C6    O6     doub N N 238 
G   C6    N1     sing N N 239 
G   N1    C2     sing N N 240 
G   N1    H1     sing N N 241 
G   C2    N2     sing N N 242 
G   C2    N3     doub N N 243 
G   N2    H21    sing N N 244 
G   N2    H22    sing N N 245 
G   N3    C4     sing N N 246 
GLN N     CA     sing N N 247 
GLN N     H      sing N N 248 
GLN N     H2     sing N N 249 
GLN CA    C      sing N N 250 
GLN CA    CB     sing N N 251 
GLN CA    HA     sing N N 252 
GLN C     O      doub N N 253 
GLN C     OXT    sing N N 254 
GLN CB    CG     sing N N 255 
GLN CB    HB2    sing N N 256 
GLN CB    HB3    sing N N 257 
GLN CG    CD     sing N N 258 
GLN CG    HG2    sing N N 259 
GLN CG    HG3    sing N N 260 
GLN CD    OE1    doub N N 261 
GLN CD    NE2    sing N N 262 
GLN NE2   HE21   sing N N 263 
GLN NE2   HE22   sing N N 264 
GLN OXT   HXT    sing N N 265 
GLU N     CA     sing N N 266 
GLU N     H      sing N N 267 
GLU N     H2     sing N N 268 
GLU CA    C      sing N N 269 
GLU CA    CB     sing N N 270 
GLU CA    HA     sing N N 271 
GLU C     O      doub N N 272 
GLU C     OXT    sing N N 273 
GLU CB    CG     sing N N 274 
GLU CB    HB2    sing N N 275 
GLU CB    HB3    sing N N 276 
GLU CG    CD     sing N N 277 
GLU CG    HG2    sing N N 278 
GLU CG    HG3    sing N N 279 
GLU CD    OE1    doub N N 280 
GLU CD    OE2    sing N N 281 
GLU OE2   HE2    sing N N 282 
GLU OXT   HXT    sing N N 283 
GLY N     CA     sing N N 284 
GLY N     H      sing N N 285 
GLY N     H2     sing N N 286 
GLY CA    C      sing N N 287 
GLY CA    HA2    sing N N 288 
GLY CA    HA3    sing N N 289 
GLY C     O      doub N N 290 
GLY C     OXT    sing N N 291 
GLY OXT   HXT    sing N N 292 
HIS N     CA     sing N N 293 
HIS N     H      sing N N 294 
HIS N     H2     sing N N 295 
HIS CA    C      sing N N 296 
HIS CA    CB     sing N N 297 
HIS CA    HA     sing N N 298 
HIS C     O      doub N N 299 
HIS C     OXT    sing N N 300 
HIS CB    CG     sing N N 301 
HIS CB    HB2    sing N N 302 
HIS CB    HB3    sing N N 303 
HIS CG    ND1    sing Y N 304 
HIS CG    CD2    doub Y N 305 
HIS ND1   CE1    doub Y N 306 
HIS ND1   HD1    sing N N 307 
HIS CD2   NE2    sing Y N 308 
HIS CD2   HD2    sing N N 309 
HIS CE1   NE2    sing Y N 310 
HIS CE1   HE1    sing N N 311 
HIS NE2   HE2    sing N N 312 
HIS OXT   HXT    sing N N 313 
ILE N     CA     sing N N 314 
ILE N     H      sing N N 315 
ILE N     H2     sing N N 316 
ILE CA    C      sing N N 317 
ILE CA    CB     sing N N 318 
ILE CA    HA     sing N N 319 
ILE C     O      doub N N 320 
ILE C     OXT    sing N N 321 
ILE CB    CG1    sing N N 322 
ILE CB    CG2    sing N N 323 
ILE CB    HB     sing N N 324 
ILE CG1   CD1    sing N N 325 
ILE CG1   HG12   sing N N 326 
ILE CG1   HG13   sing N N 327 
ILE CG2   HG21   sing N N 328 
ILE CG2   HG22   sing N N 329 
ILE CG2   HG23   sing N N 330 
ILE CD1   HD11   sing N N 331 
ILE CD1   HD12   sing N N 332 
ILE CD1   HD13   sing N N 333 
ILE OXT   HXT    sing N N 334 
LEU N     CA     sing N N 335 
LEU N     H      sing N N 336 
LEU N     H2     sing N N 337 
LEU CA    C      sing N N 338 
LEU CA    CB     sing N N 339 
LEU CA    HA     sing N N 340 
LEU C     O      doub N N 341 
LEU C     OXT    sing N N 342 
LEU CB    CG     sing N N 343 
LEU CB    HB2    sing N N 344 
LEU CB    HB3    sing N N 345 
LEU CG    CD1    sing N N 346 
LEU CG    CD2    sing N N 347 
LEU CG    HG     sing N N 348 
LEU CD1   HD11   sing N N 349 
LEU CD1   HD12   sing N N 350 
LEU CD1   HD13   sing N N 351 
LEU CD2   HD21   sing N N 352 
LEU CD2   HD22   sing N N 353 
LEU CD2   HD23   sing N N 354 
LEU OXT   HXT    sing N N 355 
LYS N     CA     sing N N 356 
LYS N     H      sing N N 357 
LYS N     H2     sing N N 358 
LYS CA    C      sing N N 359 
LYS CA    CB     sing N N 360 
LYS CA    HA     sing N N 361 
LYS C     O      doub N N 362 
LYS C     OXT    sing N N 363 
LYS CB    CG     sing N N 364 
LYS CB    HB2    sing N N 365 
LYS CB    HB3    sing N N 366 
LYS CG    CD     sing N N 367 
LYS CG    HG2    sing N N 368 
LYS CG    HG3    sing N N 369 
LYS CD    CE     sing N N 370 
LYS CD    HD2    sing N N 371 
LYS CD    HD3    sing N N 372 
LYS CE    NZ     sing N N 373 
LYS CE    HE2    sing N N 374 
LYS CE    HE3    sing N N 375 
LYS NZ    HZ1    sing N N 376 
LYS NZ    HZ2    sing N N 377 
LYS NZ    HZ3    sing N N 378 
LYS OXT   HXT    sing N N 379 
MET N     CA     sing N N 380 
MET N     H      sing N N 381 
MET N     H2     sing N N 382 
MET CA    C      sing N N 383 
MET CA    CB     sing N N 384 
MET CA    HA     sing N N 385 
MET C     O      doub N N 386 
MET C     OXT    sing N N 387 
MET CB    CG     sing N N 388 
MET CB    HB2    sing N N 389 
MET CB    HB3    sing N N 390 
MET CG    SD     sing N N 391 
MET CG    HG2    sing N N 392 
MET CG    HG3    sing N N 393 
MET SD    CE     sing N N 394 
MET CE    HE1    sing N N 395 
MET CE    HE2    sing N N 396 
MET CE    HE3    sing N N 397 
MET OXT   HXT    sing N N 398 
PHE N     CA     sing N N 399 
PHE N     H      sing N N 400 
PHE N     H2     sing N N 401 
PHE CA    C      sing N N 402 
PHE CA    CB     sing N N 403 
PHE CA    HA     sing N N 404 
PHE C     O      doub N N 405 
PHE C     OXT    sing N N 406 
PHE CB    CG     sing N N 407 
PHE CB    HB2    sing N N 408 
PHE CB    HB3    sing N N 409 
PHE CG    CD1    doub Y N 410 
PHE CG    CD2    sing Y N 411 
PHE CD1   CE1    sing Y N 412 
PHE CD1   HD1    sing N N 413 
PHE CD2   CE2    doub Y N 414 
PHE CD2   HD2    sing N N 415 
PHE CE1   CZ     doub Y N 416 
PHE CE1   HE1    sing N N 417 
PHE CE2   CZ     sing Y N 418 
PHE CE2   HE2    sing N N 419 
PHE CZ    HZ     sing N N 420 
PHE OXT   HXT    sing N N 421 
PRO N     CA     sing N N 422 
PRO N     CD     sing N N 423 
PRO N     H      sing N N 424 
PRO CA    C      sing N N 425 
PRO CA    CB     sing N N 426 
PRO CA    HA     sing N N 427 
PRO C     O      doub N N 428 
PRO C     OXT    sing N N 429 
PRO CB    CG     sing N N 430 
PRO CB    HB2    sing N N 431 
PRO CB    HB3    sing N N 432 
PRO CG    CD     sing N N 433 
PRO CG    HG2    sing N N 434 
PRO CG    HG3    sing N N 435 
PRO CD    HD2    sing N N 436 
PRO CD    HD3    sing N N 437 
PRO OXT   HXT    sing N N 438 
SER N     CA     sing N N 439 
SER N     H      sing N N 440 
SER N     H2     sing N N 441 
SER CA    C      sing N N 442 
SER CA    CB     sing N N 443 
SER CA    HA     sing N N 444 
SER C     O      doub N N 445 
SER C     OXT    sing N N 446 
SER CB    OG     sing N N 447 
SER CB    HB2    sing N N 448 
SER CB    HB3    sing N N 449 
SER OG    HG     sing N N 450 
SER OXT   HXT    sing N N 451 
THR N     CA     sing N N 452 
THR N     H      sing N N 453 
THR N     H2     sing N N 454 
THR CA    C      sing N N 455 
THR CA    CB     sing N N 456 
THR CA    HA     sing N N 457 
THR C     O      doub N N 458 
THR C     OXT    sing N N 459 
THR CB    OG1    sing N N 460 
THR CB    CG2    sing N N 461 
THR CB    HB     sing N N 462 
THR OG1   HG1    sing N N 463 
THR CG2   HG21   sing N N 464 
THR CG2   HG22   sing N N 465 
THR CG2   HG23   sing N N 466 
THR OXT   HXT    sing N N 467 
TRP N     CA     sing N N 468 
TRP N     H      sing N N 469 
TRP N     H2     sing N N 470 
TRP CA    C      sing N N 471 
TRP CA    CB     sing N N 472 
TRP CA    HA     sing N N 473 
TRP C     O      doub N N 474 
TRP C     OXT    sing N N 475 
TRP CB    CG     sing N N 476 
TRP CB    HB2    sing N N 477 
TRP CB    HB3    sing N N 478 
TRP CG    CD1    doub Y N 479 
TRP CG    CD2    sing Y N 480 
TRP CD1   NE1    sing Y N 481 
TRP CD1   HD1    sing N N 482 
TRP CD2   CE2    doub Y N 483 
TRP CD2   CE3    sing Y N 484 
TRP NE1   CE2    sing Y N 485 
TRP NE1   HE1    sing N N 486 
TRP CE2   CZ2    sing Y N 487 
TRP CE3   CZ3    doub Y N 488 
TRP CE3   HE3    sing N N 489 
TRP CZ2   CH2    doub Y N 490 
TRP CZ2   HZ2    sing N N 491 
TRP CZ3   CH2    sing Y N 492 
TRP CZ3   HZ3    sing N N 493 
TRP CH2   HH2    sing N N 494 
TRP OXT   HXT    sing N N 495 
TYR N     CA     sing N N 496 
TYR N     H      sing N N 497 
TYR N     H2     sing N N 498 
TYR CA    C      sing N N 499 
TYR CA    CB     sing N N 500 
TYR CA    HA     sing N N 501 
TYR C     O      doub N N 502 
TYR C     OXT    sing N N 503 
TYR CB    CG     sing N N 504 
TYR CB    HB2    sing N N 505 
TYR CB    HB3    sing N N 506 
TYR CG    CD1    doub Y N 507 
TYR CG    CD2    sing Y N 508 
TYR CD1   CE1    sing Y N 509 
TYR CD1   HD1    sing N N 510 
TYR CD2   CE2    doub Y N 511 
TYR CD2   HD2    sing N N 512 
TYR CE1   CZ     doub Y N 513 
TYR CE1   HE1    sing N N 514 
TYR CE2   CZ     sing Y N 515 
TYR CE2   HE2    sing N N 516 
TYR CZ    OH     sing N N 517 
TYR OH    HH     sing N N 518 
TYR OXT   HXT    sing N N 519 
U   OP3   P      sing N N 520 
U   OP3   HOP3   sing N N 521 
U   P     OP1    doub N N 522 
U   P     OP2    sing N N 523 
U   P     "O5'"  sing N N 524 
U   OP2   HOP2   sing N N 525 
U   "O5'" "C5'"  sing N N 526 
U   "C5'" "C4'"  sing N N 527 
U   "C5'" "H5'"  sing N N 528 
U   "C5'" "H5''" sing N N 529 
U   "C4'" "O4'"  sing N N 530 
U   "C4'" "C3'"  sing N N 531 
U   "C4'" "H4'"  sing N N 532 
U   "O4'" "C1'"  sing N N 533 
U   "C3'" "O3'"  sing N N 534 
U   "C3'" "C2'"  sing N N 535 
U   "C3'" "H3'"  sing N N 536 
U   "O3'" "HO3'" sing N N 537 
U   "C2'" "O2'"  sing N N 538 
U   "C2'" "C1'"  sing N N 539 
U   "C2'" "H2'"  sing N N 540 
U   "O2'" "HO2'" sing N N 541 
U   "C1'" N1     sing N N 542 
U   "C1'" "H1'"  sing N N 543 
U   N1    C2     sing N N 544 
U   N1    C6     sing N N 545 
U   C2    O2     doub N N 546 
U   C2    N3     sing N N 547 
U   N3    C4     sing N N 548 
U   N3    H3     sing N N 549 
U   C4    O4     doub N N 550 
U   C4    C5     sing N N 551 
U   C5    C6     doub N N 552 
U   C5    H5     sing N N 553 
U   C6    H6     sing N N 554 
VAL N     CA     sing N N 555 
VAL N     H      sing N N 556 
VAL N     H2     sing N N 557 
VAL CA    C      sing N N 558 
VAL CA    CB     sing N N 559 
VAL CA    HA     sing N N 560 
VAL C     O      doub N N 561 
VAL C     OXT    sing N N 562 
VAL CB    CG1    sing N N 563 
VAL CB    CG2    sing N N 564 
VAL CB    HB     sing N N 565 
VAL CG1   HG11   sing N N 566 
VAL CG1   HG12   sing N N 567 
VAL CG1   HG13   sing N N 568 
VAL CG2   HG21   sing N N 569 
VAL CG2   HG22   sing N N 570 
VAL CG2   HG23   sing N N 571 
VAL OXT   HXT    sing N N 572 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-23 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZMI 
_em_admin.last_update        2025-03-12 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'Cryo-EM structure of BMV TLS-TyrRS-ATP(Pre-1a state)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    YES 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.12 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 3885  'Phaseolus vulgaris' ? ? ? ? ? 
? ? 1 3 12302 'Brome mosaic virus' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 1 2 561    'Escherichia coli'                               ? ? 
? 1 3 905932 'in vitro transcription vector pT7-Fluc(deltai)' ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   3980856 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC 4.2 
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU       ?   
MASKING                    ? 3  ? ? ? ?         ?   
'CTF CORRECTION'           ? 4  1 ? ? ?         ?   
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?   
'MODEL FITTING'            ? 7  ? ? ? ?         ?   
'MODEL REFINEMENT'         ? 8  ? ? ? ?         ?   
OTHER                      ? 9  ? ? ? ?         ?   
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?         ?   
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?         ?   
CLASSIFICATION             ? 12 1 ? ? ?         ?   
RECONSTRUCTION             ? 13 1 ? ? ?         ?   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
8ZMI 'double helix'        
8ZMI 'a-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 C A 9   1_555 C G 5   1_555 -6.716 -3.043 -0.409 -5.101  6.847   -14.181 1  C_A9:G5_C     C 9   ? C 5   ? 11 10 
1 C C 10  1_555 C G 4   1_555 0.133  -0.225 -0.836 5.005   4.102   -2.008  2  C_C10:G4_C    C 10  ? C 4   ? 19 1  
1 C A 11  1_555 C U 3   1_555 0.075  -0.165 -0.740 -0.416  -0.022  -2.270  3  C_A11:U3_C    C 11  ? C 3   ? 20 1  
1 C C 12  1_555 C G 2   1_555 0.173  -0.212 -0.801 5.453   -2.119  0.854   4  C_C12:G2_C    C 12  ? C 2   ? 19 1  
1 C G 13  1_555 C C 1   1_555 -0.162 -0.363 -1.184 8.176   -0.475  0.962   5  C_G13:C1_C    C 13  ? C 1   ? 19 1  
1 C A 15  1_555 C U 35  1_555 0.095  -0.083 0.329  -1.912  -5.923  -3.381  6  C_A15:U35_C   C 15  ? C 35  ? 20 1  
1 C G 16  1_555 C C 34  1_555 -0.196 -0.149 -0.535 -5.313  -5.177  2.411   7  C_G16:C34_C   C 16  ? C 34  ? 19 1  
1 C A 17  1_555 C U 33  1_555 0.100  -0.081 -0.452 -11.793 -1.051  0.410   8  C_A17:U33_C   C 17  ? C 33  ? 20 1  
1 C C 18  1_555 C G 32  1_555 0.235  -0.121 0.372  -14.042 9.267   1.047   9  C_C18:G32_C   C 18  ? C 32  ? 19 1  
1 C C 19  1_555 C G 30  1_555 0.144  -0.117 0.248  0.129   -2.574  0.573   10 C_C19:G30_C   C 19  ? C 30  ? 19 1  
1 C U 20  1_555 C A 29  1_555 -0.157 -0.131 -0.383 -3.612  7.149   -2.549  11 C_U20:A29_C   C 20  ? C 29  ? 20 1  
1 C C 21  1_555 C G 28  1_555 0.205  -0.122 -0.098 0.645   19.835  2.627   12 C_C21:G28_C   C 21  ? C 28  ? 19 1  
1 C U 22  1_555 C A 27  1_555 -0.488 -0.223 -1.088 15.984  26.128  -9.182  13 C_U22:A27_C   C 22  ? C 27  ? 20 1  
1 C A 126 1_555 C U 39  1_555 0.571  0.078  -0.677 -6.681  -1.862  -3.308  14 C_A126:U39_C  C 126 ? C 39  ? 20 1  
1 C C 127 1_555 C G 38  1_555 0.126  -0.315 -1.059 0.293   1.887   -1.690  15 C_C127:G38_C  C 127 ? C 38  ? 19 1  
1 C C 128 1_555 C G 37  1_555 0.193  -0.168 -0.632 5.912   -3.572  1.236   16 C_C128:G37_C  C 128 ? C 37  ? 19 1  
1 C U 130 1_555 C A 151 1_555 -0.079 -0.119 -0.400 -2.192  -3.866  6.120   17 C_U130:A151_C C 130 ? C 151 ? 20 1  
1 C A 131 1_555 C U 150 1_555 0.042  -0.120 0.274  -1.254  -2.326  3.465   18 C_A131:U150_C C 131 ? C 150 ? 20 1  
1 C C 132 1_555 C G 149 1_555 0.178  -0.161 -0.389 0.032   -1.701  0.068   19 C_C132:G149_C C 132 ? C 149 ? 19 1  
1 C A 133 1_555 C U 148 1_555 0.014  -0.137 0.517  1.000   8.723   4.636   20 C_A133:U148_C C 133 ? C 148 ? 20 1  
1 C G 134 1_555 C C 147 1_555 -0.174 -0.220 -0.872 -3.728  -0.684  1.433   21 C_G134:C147_C C 134 ? C 147 ? 19 1  
1 C U 135 1_555 C A 146 1_555 -0.044 -0.185 -0.741 0.406   0.181   2.222   22 C_U135:A146_C C 135 ? C 146 ? 20 1  
1 C G 136 1_555 C C 145 1_555 -0.125 -0.294 -1.153 -7.948  1.201   0.299   23 C_G136:C145_C C 136 ? C 145 ? 19 1  
1 C U 137 1_555 C A 144 1_555 -0.183 -0.363 -1.231 -2.616  8.511   -6.248  24 C_U137:A144_C C 137 ? C 144 ? 20 1  
1 C U 138 1_555 C A 143 1_555 -0.047 -0.162 -0.572 0.452   2.122   1.166   25 C_U138:A143_C C 138 ? C 143 ? 20 1  
1 C G 139 1_555 C A 142 1_555 6.716  -4.334 -1.036 5.558   3.437   -12.425 26 C_G139:A142_C C 139 ? C 142 ? 11 10 
1 C G 46  1_555 C C 65  1_555 -0.734 0.702  -2.061 -13.242 -25.367 -21.103 27 C_G46:C65_C   C 46  ? C 65  ? ?  ?  
1 C A 47  1_555 C U 64  1_555 0.605  0.518  -1.734 -22.816 -11.670 -18.917 28 C_A47:U64_C   C 47  ? C 64  ? 20 1  
1 C G 48  1_555 C C 63  1_555 -3.906 -0.423 -0.309 5.380   -11.924 17.394  29 C_G48:C63_C   C 48  ? C 63  ? ?  ?  
1 C A 49  1_555 C U 62  1_555 0.524  0.650  -1.506 1.285   -11.252 -23.035 30 C_A49:U62_C   C 49  ? C 62  ? ?  ?  
1 C G 50  1_555 C C 61  1_555 -0.207 -0.215 -0.752 -7.877  -5.701  0.996   31 C_G50:C61_C   C 50  ? C 61  ? 19 1  
1 C U 51  1_555 C G 60  1_555 1.961  -0.481 -0.560 -3.466  -3.617  -4.117  32 C_U51:G60_C   C 51  ? C 60  ? 28 1  
1 C A 160 1_555 C U 59  1_555 0.089  -0.149 0.555  -0.186  -4.959  -2.495  33 C_A160:U59_C  C 160 ? C 59  ? 20 1  
1 C A 161 1_555 C U 58  1_555 0.061  -0.091 0.071  0.696   -1.898  0.926   34 C_A161:U58_C  C 161 ? C 58  ? 20 1  
1 C A 162 1_555 C U 57  1_555 0.046  -0.136 -0.460 2.768   -5.571  1.813   35 C_A162:U57_C  C 162 ? C 57  ? 20 1  
1 C G 163 1_555 C C 56  1_555 -0.163 -0.143 -0.274 -0.833  -2.986  0.739   36 C_G163:C56_C  C 163 ? C 56  ? 19 1  
1 C A 164 1_555 C U 55  1_555 0.086  -0.099 -0.224 0.145   1.615   -1.131  37 C_A164:U55_C  C 164 ? C 55  ? 20 1  
1 C G 165 1_555 C C 54  1_555 -0.173 -0.318 -0.891 12.066  3.895   -1.149  38 C_G165:C54_C  C 165 ? C 54  ? 19 1  
1 C A 72  1_555 C G 124 1_555 -6.997 -7.136 -0.310 -2.711  -17.957 -40.259 39 C_A72:G124_C  C 72  ? C 124 ? ?  10 
1 C C 42  1_555 C G 123 1_555 0.200  -0.165 -0.752 -6.559  -0.367  1.008   40 C_C42:G123_C  C 42  ? C 123 ? 19 1  
1 C U 43  1_555 C G 122 1_555 0.930  0.459  -0.139 -2.310  2.071   2.137   41 C_U43:G122_C  C 43  ? C 122 ? ?  1  
1 C G 91  1_555 C C 121 1_555 -0.380 -0.730 -0.313 -4.230  -2.393  -0.298  42 C_G91:C121_C  C 91  ? C 121 ? 19 1  
1 C C 92  1_555 C G 120 1_555 0.201  -0.123 -0.203 -1.221  -2.318  0.753   43 C_C92:G120_C  C 92  ? C 120 ? 19 1  
1 C A 93  1_555 C U 119 1_555 0.019  -0.072 -0.312 -0.843  -2.639  -1.387  44 C_A93:U119_C  C 93  ? C 119 ? 20 1  
1 C U 94  1_555 C A 118 1_555 0.041  -0.181 -1.098 0.625   -2.575  -1.894  45 C_U94:A118_C  C 94  ? C 118 ? 20 1  
1 C G 73  1_555 C C 88  1_555 -0.624 0.391  -1.115 -13.912 -6.913  15.335  46 C_G73:C88_C   C 73  ? C 88  ? ?  1  
1 C A 74  1_555 C U 87  1_555 0.004  -0.097 -0.181 -7.583  -1.749  -2.079  47 C_A74:U87_C   C 74  ? C 87  ? 20 1  
1 C A 75  1_555 C U 86  1_555 0.054  -0.116 0.093  -5.420  2.833   -0.379  48 C_A75:U86_C   C 75  ? C 86  ? 20 1  
1 C C 76  1_555 C G 85  1_555 0.211  -0.128 0.442  -0.130  6.194   2.799   49 C_C76:G85_C   C 76  ? C 85  ? 19 1  
1 C C 77  1_555 C G 84  1_555 0.219  -0.183 0.607  1.962   6.094   3.271   50 C_C77:G84_C   C 77  ? C 84  ? 19 1  
1 C C 78  1_555 C G 83  1_555 0.210  -0.221 0.735  3.946   4.721   2.723   51 C_C78:G83_C   C 78  ? C 83  ? 19 1  
1 C G 97  1_555 C C 112 1_555 -0.215 -0.154 0.652  -11.349 10.605  6.137   52 C_G97:C112_C  C 97  ? C 112 ? 19 1  
1 C C 98  1_555 C G 110 1_555 -0.072 -0.558 -1.593 5.550   12.306  -10.884 53 C_C98:G110_C  C 98  ? C 110 ? 19 1  
1 C U 99  1_555 C A 109 1_555 -0.065 -0.188 -0.614 -5.141  -3.321  -0.663  54 C_U99:A109_C  C 99  ? C 109 ? 20 1  
1 C U 100 1_555 C A 108 1_555 -0.112 -0.191 -0.846 -0.298  2.603   -3.563  55 C_U100:A108_C C 100 ? C 108 ? 20 1  
1 C G 101 1_555 C C 107 1_555 -0.172 -0.165 -0.085 5.030   9.374   -0.644  56 C_G101:C107_C C 101 ? C 107 ? 19 1  
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 C A 9   1_555 C G 5   1_555 C C 10  1_555 C G 4   1_555 -0.330 -1.189 3.317 -1.920  2.980  58.098 -1.380 0.238  3.266  3.066  
1.975   58.196 1  CC_A9C10:G4G5_CC        C 9   ? C 5   ? C 10  ? C 4   ? 
1 C C 10  1_555 C G 4   1_555 C A 11  1_555 C U 3   1_555 -0.194 -1.046 3.552 1.381   41.665 36.230 -3.613 0.293  1.629  50.736 
-1.681  54.696 2  CC_C10A11:U3G4_CC       C 10  ? C 4   ? C 11  ? C 3   ? 
1 C A 11  1_555 C U 3   1_555 C C 12  1_555 C G 2   1_555 0.346  -1.672 3.074 1.209   2.046  34.241 -3.130 -0.410 2.982  3.470  
-2.050  34.321 3  CC_A11C12:G2U3_CC       C 11  ? C 3   ? C 12  ? C 2   ? 
1 C C 12  1_555 C G 2   1_555 C G 13  1_555 C C 1   1_555 -0.768 -0.168 3.223 3.951   34.176 25.436 -3.601 1.447  1.753  54.222 
-6.268  42.556 4  CC_C12G13:C1G2_CC       C 12  ? C 2   ? C 13  ? C 1   ? 
1 C G 13  1_555 C C 1   1_555 C A 15  1_555 C U 35  1_555 -1.331 -4.740 4.602 -13.158 25.316 63.086 -5.351 0.585  2.933  23.000 
11.954  68.626 5  CC_G13A15:U35C1_CC      C 13  ? C 1   ? C 15  ? C 35  ? 
1 C A 15  1_555 C U 35  1_555 C G 16  1_555 C C 34  1_555 0.218  -1.429 3.757 -1.611  0.544  31.333 -2.759 -0.749 3.717  1.007  
2.980   31.378 6  CC_A15G16:C34U35_CC     C 15  ? C 35  ? C 16  ? C 34  ? 
1 C G 16  1_555 C C 34  1_555 C A 17  1_555 C U 33  1_555 -0.333 -1.530 3.418 -3.354  1.018  34.268 -2.750 0.018  3.388  1.722  
5.673   34.441 7  CC_G16A17:U33C34_CC     C 16  ? C 34  ? C 17  ? C 33  ? 
1 C A 17  1_555 C U 33  1_555 C C 18  1_555 C G 32  1_555 0.238  -1.704 3.374 -5.885  2.536  36.913 -2.989 -1.151 3.180  3.968  
9.209   37.446 8  CC_A17C18:G32U33_CC     C 17  ? C 33  ? C 18  ? C 32  ? 
1 C C 18  1_555 C G 32  1_555 C C 19  1_555 C G 30  1_555 0.501  -2.228 3.873 -19.514 20.067 39.435 -4.352 -2.186 2.122  26.136 
25.415  48.035 9  CC_C18C19:G30G32_CC     C 18  ? C 32  ? C 19  ? C 30  ? 
1 C C 19  1_555 C G 30  1_555 C U 20  1_555 C A 29  1_555 -1.226 -2.302 3.281 -2.172  3.801  31.650 -4.855 1.844  3.065  6.928  
3.959   31.944 10 CC_C19U20:A29G30_CC     C 19  ? C 30  ? C 20  ? C 29  ? 
1 C U 20  1_555 C A 29  1_555 C C 21  1_555 C G 28  1_555 0.189  -1.841 3.125 -3.610  6.665  30.911 -4.450 -0.936 2.642  12.276 
6.649   31.805 11 CC_U20C21:G28A29_CC     C 20  ? C 29  ? C 21  ? C 28  ? 
1 C C 21  1_555 C G 28  1_555 C U 22  1_555 C A 27  1_555 -2.705 -1.641 2.743 3.377   23.199 30.533 -4.367 4.393  0.998  37.839 
-5.509  38.324 12 CC_C21U22:A27G28_CC     C 21  ? C 28  ? C 22  ? C 27  ? 
1 C A 126 1_555 C U 39  1_555 C C 127 1_555 C G 38  1_555 -0.350 -1.596 3.190 0.768   1.932  30.833 -3.354 0.800  3.077  3.629  
-1.442  30.902 13 CC_A126C127:G38U39_CC   C 126 ? C 39  ? C 127 ? C 38  ? 
1 C C 127 1_555 C G 38  1_555 C C 128 1_555 C G 37  1_555 0.370  -1.176 3.259 0.934   5.212  29.618 -3.299 -0.529 3.022  10.093 
-1.808  30.077 14 CC_C127C128:G37G38_CC   C 127 ? C 38  ? C 128 ? C 37  ? 
1 C C 128 1_555 C G 37  1_555 C U 130 1_555 C A 151 1_555 1.675  -2.580 6.110 8.051   24.673 67.072 -3.726 -0.942 5.166  21.525 
-7.024  71.367 15 CC_C128U130:A151G37_CC  C 128 ? C 37  ? C 130 ? C 151 ? 
1 C U 130 1_555 C A 151 1_555 C A 131 1_555 C U 150 1_555 -0.224 -0.846 3.104 -5.479  24.961 29.535 -3.932 -0.247 1.878  40.691 
8.932   38.870 16 CC_U130A131:U150A151_CC C 130 ? C 151 ? C 131 ? C 150 ? 
1 C A 131 1_555 C U 150 1_555 C C 132 1_555 C G 149 1_555 -0.314 -1.539 3.545 1.416   0.967  33.338 -2.852 0.799  3.484  1.685  
-2.465  33.381 17 CC_A131C132:G149U150_CC C 131 ? C 150 ? C 132 ? C 149 ? 
1 C C 132 1_555 C G 149 1_555 C A 133 1_555 C U 148 1_555 -0.020 -1.515 2.937 -7.868  20.656 30.124 -4.488 -0.773 1.575  34.510 
13.145  37.212 18 CC_C132A133:U148G149_CC C 132 ? C 149 ? C 133 ? C 148 ? 
1 C A 133 1_555 C U 148 1_555 C G 134 1_555 C C 147 1_555 -0.311 -1.639 3.722 5.113   11.461 27.356 -5.597 1.686  2.730  22.774 
-10.161 30.048 19 CC_A133G134:C147U148_CC C 133 ? C 148 ? C 134 ? C 147 ? 
1 C G 134 1_555 C C 147 1_555 C U 135 1_555 C A 146 1_555 -0.231 -1.528 3.493 -2.107  1.648  29.905 -3.308 -0.013 3.414  3.186  
4.073   30.021 20 CC_G134U135:A146C147_CC C 134 ? C 147 ? C 135 ? C 146 ? 
1 C U 135 1_555 C A 146 1_555 C G 136 1_555 C C 145 1_555 -0.031 -0.734 3.636 1.257   31.927 30.957 -4.095 0.164  2.061  46.974 
-1.849  44.206 21 CC_U135G136:C145A146_CC C 135 ? C 146 ? C 136 ? C 145 ? 
1 C G 136 1_555 C C 145 1_555 C U 137 1_555 C A 144 1_555 -0.773 -1.620 3.414 -1.639  2.787  30.475 -3.630 1.130  3.292  5.283  
3.107   30.642 22 CC_G136U137:A144C145_CC C 136 ? C 145 ? C 137 ? C 144 ? 
1 C U 137 1_555 C A 144 1_555 C U 138 1_555 C A 143 1_555 0.514  -1.377 3.495 0.548   9.922  29.381 -4.499 -0.856 2.896  18.893 
-1.044  30.981 23 CC_U137U138:A143A144_CC C 137 ? C 144 ? C 138 ? C 143 ? 
1 C U 138 1_555 C A 143 1_555 C G 139 1_555 C A 142 1_555 0.905  -1.258 3.598 -2.691  2.804  39.555 -2.202 -1.669 3.439  4.131  
3.964   39.738 24 CC_U138G139:A142A143_CC C 138 ? C 143 ? C 139 ? C 142 ? 
1 C G 46  1_555 C C 65  1_555 C A 47  1_555 C U 64  1_555 0.216  -1.508 3.765 -0.901  22.457 32.998 -4.893 -0.426 2.313  34.949 
1.403   39.749 25 CC_G46A47:U64C65_CC     C 46  ? C 65  ? C 47  ? C 64  ? 
1 C A 47  1_555 C U 64  1_555 C G 48  1_555 C C 63  1_555 2.055  -0.745 2.479 -12.491 7.687  11.710 -4.110 -9.270 -0.116 27.044 
43.942  18.748 26 CC_A47G48:C63U64_CC     C 47  ? C 64  ? C 48  ? C 63  ? 
1 C G 48  1_555 C C 63  1_555 C A 49  1_555 C U 62  1_555 -2.876 -1.336 3.418 1.968   5.389  50.855 -1.923 3.468  3.164  6.252  
-2.283  51.156 27 CC_G48A49:U62C63_CC     C 48  ? C 63  ? C 49  ? C 62  ? 
1 C A 49  1_555 C U 62  1_555 C G 50  1_555 C C 61  1_555 0.859  -1.332 3.459 -8.764  18.544 26.902 -5.031 -2.773 1.836  34.243 
16.184  33.714 28 CC_A49G50:C61U62_CC     C 49  ? C 62  ? C 50  ? C 61  ? 
1 C G 50  1_555 C C 61  1_555 C U 51  1_555 C G 60  1_555 -0.140 -1.189 3.296 1.847   -0.795 44.537 -1.494 0.356  3.308  -1.049 
-2.435  44.580 29 CC_G50U51:G60C61_CC     C 50  ? C 61  ? C 51  ? C 60  ? 
1 C U 51  1_555 C G 60  1_555 C A 160 1_555 C U 59  1_555 -0.927 -1.649 3.212 -1.741  0.521  35.932 -2.742 1.257  3.228  0.845  
2.819   35.976 30 CC_U51A160:U59G60_CC    C 51  ? C 60  ? C 160 ? C 59  ? 
1 C A 160 1_555 C U 59  1_555 C A 161 1_555 C U 58  1_555 -1.234 -2.284 3.112 -1.169  14.624 21.247 -8.191 2.522  1.347  34.815 
2.782   25.772 31 CC_A160A161:U58U59_CC   C 160 ? C 59  ? C 161 ? C 58  ? 
1 C A 161 1_555 C U 58  1_555 C A 162 1_555 C U 57  1_555 0.073  -1.209 3.399 3.076   4.106  32.324 -2.868 0.411  3.218  7.318  
-5.483  32.718 32 CC_A161A162:U57U58_CC   C 161 ? C 58  ? C 162 ? C 57  ? 
1 C A 162 1_555 C U 57  1_555 C G 163 1_555 C C 56  1_555 0.140  -1.474 3.189 -1.617  12.276 31.622 -4.293 -0.472 2.454  21.522 
2.836   33.902 33 CC_A162G163:C56U57_CC   C 162 ? C 57  ? C 163 ? C 56  ? 
1 C G 163 1_555 C C 56  1_555 C A 164 1_555 C U 55  1_555 0.610  -1.282 3.130 0.361   5.674  40.709 -2.400 -0.832 2.938  8.108  
-0.516  41.087 34 CC_G163A164:U55C56_CC   C 163 ? C 56  ? C 164 ? C 55  ? 
1 C A 164 1_555 C U 55  1_555 C G 165 1_555 C C 54  1_555 0.304  -1.257 3.502 9.066   8.205  24.440 -4.772 1.684  2.870  18.011 
-19.901 27.286 35 CC_A164G165:C54U55_CC   C 164 ? C 55  ? C 165 ? C 54  ? 
1 C A 72  1_555 C G 124 1_555 C C 42  1_555 C G 123 1_555 4.629  1.954  3.218 -12.054 5.966  57.976 1.707  -5.211 2.469  6.066  
12.255  59.383 36 CC_A72C42:G123G124_CC   C 72  ? C 124 ? C 42  ? C 123 ? 
1 C C 42  1_555 C G 123 1_555 C U 43  1_555 C G 122 1_555 0.501  -1.465 3.090 -0.897  3.377  33.723 -3.013 -0.992 2.920  5.802  
1.541   33.898 37 CC_C42U43:G122G123_CC   C 42  ? C 123 ? C 43  ? C 122 ? 
1 C U 43  1_555 C G 122 1_555 C G 91  1_555 C C 121 1_555 -1.340 -1.368 2.992 -0.327  17.078 33.066 -4.030 2.070  2.075  27.817 
0.532   37.107 38 CC_U43G91:C121G122_CC   C 43  ? C 122 ? C 91  ? C 121 ? 
1 C G 91  1_555 C C 121 1_555 C C 92  1_555 C G 120 1_555 -0.533 -0.772 3.184 -2.859  0.560  38.488 -1.235 0.461  3.203  0.848  
4.329   38.594 39 CC_G91C92:G120C121_CC   C 91  ? C 121 ? C 92  ? C 120 ? 
1 C C 92  1_555 C G 120 1_555 C A 93  1_555 C U 119 1_555 -0.790 -1.193 3.206 -5.722  34.374 27.531 -4.340 0.593  1.219  52.114 
8.676   44.144 40 CC_C92A93:U119G120_CC   C 92  ? C 120 ? C 93  ? C 119 ? 
1 C A 93  1_555 C U 119 1_555 C U 94  1_555 C A 118 1_555 -0.424 -1.442 3.506 1.092   0.902  32.455 -2.746 0.962  3.450  1.614  
-1.954  32.485 41 CC_A93U94:A118U119_CC   C 93  ? C 119 ? C 94  ? C 118 ? 
1 C G 73  1_555 C C 88  1_555 C A 74  1_555 C U 87  1_555 -1.907 -1.200 2.965 -13.047 6.638  31.870 -2.983 1.231  3.179  11.369 
22.346  34.992 42 CC_G73A74:U87C88_CC     C 73  ? C 88  ? C 74  ? C 87  ? 
1 C A 74  1_555 C U 87  1_555 C A 75  1_555 C U 86  1_555 -0.288 -1.302 3.119 -3.739  4.601  33.363 -2.925 -0.066 2.933  7.935  
6.449   33.871 43 CC_A74A75:U86U87_CC     C 74  ? C 87  ? C 75  ? C 86  ? 
1 C A 75  1_555 C U 86  1_555 C C 76  1_555 C G 85  1_555 0.831  -1.558 3.141 -1.442  4.217  32.966 -3.374 -1.674 2.887  7.390  
2.526   33.258 44 CC_A75C76:G85U86_CC     C 75  ? C 86  ? C 76  ? C 85  ? 
1 C C 76  1_555 C G 85  1_555 C C 77  1_555 C G 84  1_555 0.172  -1.925 3.121 0.418   4.046  28.808 -4.643 -0.259 2.832  8.081  
-0.836  29.087 45 CC_C76C77:G84G85_CC     C 76  ? C 85  ? C 77  ? C 84  ? 
1 C C 77  1_555 C G 84  1_555 C C 78  1_555 C G 83  1_555 0.292  -1.957 3.188 1.634   3.517  31.307 -4.217 -0.249 2.967  6.485  
-3.014  31.541 46 CC_C77C78:G83G84_CC     C 77  ? C 84  ? C 78  ? C 83  ? 
1 C G 97  1_555 C C 112 1_555 C C 98  1_555 C G 110 1_555 2.320  -1.588 4.774 -10.597 12.913 41.571 -3.644 -4.329 3.494  17.374 
14.258  44.663 47 CC_G97C98:G110C112_CC   C 97  ? C 112 ? C 98  ? C 110 ? 
1 C C 98  1_555 C G 110 1_555 C U 99  1_555 C A 109 1_555 2.240  -1.573 3.399 10.341  63.906 43.188 -3.063 -1.519 1.060  59.091 
-9.562  76.496 48 CC_C98U99:A109G110_CC   C 98  ? C 110 ? C 99  ? C 109 ? 
1 C U 99  1_555 C A 109 1_555 C U 100 1_555 C A 108 1_555 0.258  -1.183 3.403 1.291   2.744  31.152 -2.725 -0.229 3.297  5.095  
-2.397  31.295 49 CC_U99U100:A108A109_CC  C 99  ? C 109 ? C 100 ? C 108 ? 
1 C U 100 1_555 C A 108 1_555 C G 101 1_555 C C 107 1_555 0.666  -1.574 3.544 1.388   5.112  28.986 -4.240 -1.000 3.252  10.107 
-2.745  29.456 50 CC_U100G101:C107A108_CC C 100 ? C 108 ? C 101 ? C 107 ? 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8ZMI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . PRO A 1 31  ? 158.908 123.424 171.209 1.00 53.23  ? 31  PRO A N     1 
ATOM   2    C CA    . PRO A 1 31  ? 157.894 123.361 170.150 1.00 53.23  ? 31  PRO A CA    1 
ATOM   3    C C     . PRO A 1 31  ? 156.503 123.028 170.684 1.00 53.23  ? 31  PRO A C     1 
ATOM   4    O O     . PRO A 1 31  ? 155.581 123.827 170.520 1.00 53.23  ? 31  PRO A O     1 
ATOM   5    C CB    . PRO A 1 31  ? 158.410 122.250 169.232 1.00 53.23  ? 31  PRO A CB    1 
ATOM   6    C CG    . PRO A 1 31  ? 159.293 121.415 170.090 1.00 53.23  ? 31  PRO A CG    1 
ATOM   7    C CD    . PRO A 1 31  ? 159.892 122.334 171.110 1.00 53.23  ? 31  PRO A CD    1 
ATOM   8    N N     . GLU A 1 32  ? 156.354 121.861 171.314 1.00 46.17  ? 32  GLU A N     1 
ATOM   9    C CA    . GLU A 1 32  ? 155.058 121.491 171.869 1.00 46.17  ? 32  GLU A CA    1 
ATOM   10   C C     . GLU A 1 32  ? 154.668 122.393 173.032 1.00 46.17  ? 32  GLU A C     1 
ATOM   11   O O     . GLU A 1 32  ? 153.484 122.712 173.197 1.00 46.17  ? 32  GLU A O     1 
ATOM   12   C CB    . GLU A 1 32  ? 155.068 120.028 172.308 1.00 46.17  ? 32  GLU A CB    1 
ATOM   13   C CG    . GLU A 1 32  ? 153.688 119.469 172.593 1.00 46.17  ? 32  GLU A CG    1 
ATOM   14   C CD    . GLU A 1 32  ? 152.845 119.345 171.339 1.00 46.17  ? 32  GLU A CD    1 
ATOM   15   O OE1   . GLU A 1 32  ? 153.407 119.015 170.274 1.00 46.17  ? 32  GLU A OE1   1 
ATOM   16   O OE2   . GLU A 1 32  ? 151.621 119.578 171.418 1.00 46.17  ? 32  GLU A OE2   1 
ATOM   17   N N     . GLU A 1 33  ? 155.640 122.810 173.847 1.00 50.39  ? 33  GLU A N     1 
ATOM   18   C CA    . GLU A 1 33  ? 155.349 123.773 174.904 1.00 50.39  ? 33  GLU A CA    1 
ATOM   19   C C     . GLU A 1 33  ? 154.861 125.091 174.319 1.00 50.39  ? 33  GLU A C     1 
ATOM   20   O O     . GLU A 1 33  ? 153.900 125.687 174.823 1.00 50.39  ? 33  GLU A O     1 
ATOM   21   C CB    . GLU A 1 33  ? 156.591 123.998 175.767 1.00 50.39  ? 33  GLU A CB    1 
ATOM   22   C CG    . GLU A 1 33  ? 157.330 122.726 176.146 1.00 50.39  ? 33  GLU A CG    1 
ATOM   23   C CD    . GLU A 1 33  ? 158.448 122.394 175.177 1.00 50.39  ? 33  GLU A CD    1 
ATOM   24   O OE1   . GLU A 1 33  ? 158.657 123.169 174.220 1.00 50.39  ? 33  GLU A OE1   1 
ATOM   25   O OE2   . GLU A 1 33  ? 159.119 121.359 175.374 1.00 50.39  ? 33  GLU A OE2   1 
ATOM   26   N N     . LYS A 1 34  ? 155.512 125.558 173.250 1.00 41.26  ? 34  LYS A N     1 
ATOM   27   C CA    . LYS A 1 34  ? 155.065 126.774 172.581 1.00 41.26  ? 34  LYS A CA    1 
ATOM   28   C C     . LYS A 1 34  ? 153.653 126.612 172.040 1.00 41.26  ? 34  LYS A C     1 
ATOM   29   O O     . LYS A 1 34  ? 152.827 127.524 172.158 1.00 41.26  ? 34  LYS A O     1 
ATOM   30   C CB    . LYS A 1 34  ? 156.026 127.140 171.450 1.00 41.26  ? 34  LYS A CB    1 
ATOM   31   C CG    . LYS A 1 34  ? 157.377 127.653 171.911 1.00 41.26  ? 34  LYS A CG    1 
ATOM   32   C CD    . LYS A 1 34  ? 158.236 128.059 170.724 1.00 41.26  ? 34  LYS A CD    1 
ATOM   33   C CE    . LYS A 1 34  ? 159.585 128.597 171.171 1.00 41.26  ? 34  LYS A CE    1 
ATOM   34   N NZ    . LYS A 1 34  ? 160.392 129.087 170.020 1.00 41.26  ? 34  LYS A NZ    1 
ATOM   35   N N     . PHE A 1 35  ? 153.359 125.457 171.439 1.00 39.14  ? 35  PHE A N     1 
ATOM   36   C CA    . PHE A 1 35  ? 152.022 125.229 170.904 1.00 39.14  ? 35  PHE A CA    1 
ATOM   37   C C     . PHE A 1 35  ? 150.973 125.237 172.006 1.00 39.14  ? 35  PHE A C     1 
ATOM   38   O O     . PHE A 1 35  ? 149.895 125.817 171.838 1.00 39.14  ? 35  PHE A O     1 
ATOM   39   C CB    . PHE A 1 35  ? 151.969 123.910 170.143 1.00 39.14  ? 35  PHE A CB    1 
ATOM   40   C CG    . PHE A 1 35  ? 150.583 123.364 169.992 1.00 39.14  ? 35  PHE A CG    1 
ATOM   41   C CD1   . PHE A 1 35  ? 149.723 123.883 169.045 1.00 39.14  ? 35  PHE A CD1   1 
ATOM   42   C CD2   . PHE A 1 35  ? 150.137 122.335 170.803 1.00 39.14  ? 35  PHE A CD2   1 
ATOM   43   C CE1   . PHE A 1 35  ? 148.448 123.387 168.906 1.00 39.14  ? 35  PHE A CE1   1 
ATOM   44   C CE2   . PHE A 1 35  ? 148.862 121.836 170.668 1.00 39.14  ? 35  PHE A CE2   1 
ATOM   45   C CZ    . PHE A 1 35  ? 148.017 122.361 169.718 1.00 39.14  ? 35  PHE A CZ    1 
ATOM   46   N N     . LYS A 1 36  ? 151.260 124.583 173.133 1.00 36.31  ? 36  LYS A N     1 
ATOM   47   C CA    . LYS A 1 36  ? 150.307 124.571 174.239 1.00 36.31  ? 36  LYS A CA    1 
ATOM   48   C C     . LYS A 1 36  ? 150.087 125.974 174.790 1.00 36.31  ? 36  LYS A C     1 
ATOM   49   O O     . LYS A 1 36  ? 148.944 126.380 175.043 1.00 36.31  ? 36  LYS A O     1 
ATOM   50   C CB    . LYS A 1 36  ? 150.792 123.630 175.341 1.00 36.31  ? 36  LYS A CB    1 
ATOM   51   C CG    . LYS A 1 36  ? 150.481 122.164 175.087 1.00 36.31  ? 36  LYS A CG    1 
ATOM   52   C CD    . LYS A 1 36  ? 149.100 121.798 175.604 1.00 36.31  ? 36  LYS A CD    1 
ATOM   53   C CE    . LYS A 1 36  ? 149.119 121.566 177.106 1.00 36.31  ? 36  LYS A CE    1 
ATOM   54   N NZ    . LYS A 1 36  ? 147.751 121.601 177.691 1.00 36.31  ? 36  LYS A NZ    1 
ATOM   55   N N     . ILE A 1 37  ? 151.169 126.738 174.959 1.00 36.16  ? 37  ILE A N     1 
ATOM   56   C CA    . ILE A 1 37  ? 151.046 128.100 175.470 1.00 36.16  ? 37  ILE A CA    1 
ATOM   57   C C     . ILE A 1 37  ? 150.214 128.953 174.521 1.00 36.16  ? 37  ILE A C     1 
ATOM   58   O O     . ILE A 1 37  ? 149.333 129.707 174.952 1.00 36.16  ? 37  ILE A O     1 
ATOM   59   C CB    . ILE A 1 37  ? 152.441 128.708 175.705 1.00 36.16  ? 37  ILE A CB    1 
ATOM   60   C CG1   . ILE A 1 37  ? 153.105 128.058 176.920 1.00 36.16  ? 37  ILE A CG1   1 
ATOM   61   C CG2   . ILE A 1 37  ? 152.345 130.209 175.894 1.00 36.16  ? 37  ILE A CG2   1 
ATOM   62   C CD1   . ILE A 1 37  ? 154.402 128.719 177.331 1.00 36.16  ? 37  ILE A CD1   1 
ATOM   63   N N     . VAL A 1 38  ? 150.471 128.843 173.216 1.00 34.50  ? 38  VAL A N     1 
ATOM   64   C CA    . VAL A 1 38  ? 149.737 129.646 172.244 1.00 34.50  ? 38  VAL A CA    1 
ATOM   65   C C     . VAL A 1 38  ? 148.267 129.245 172.211 1.00 34.50  ? 38  VAL A C     1 
ATOM   66   O O     . VAL A 1 38  ? 147.378 130.105 172.202 1.00 34.50  ? 38  VAL A O     1 
ATOM   67   C CB    . VAL A 1 38  ? 150.392 129.527 170.857 1.00 34.50  ? 38  VAL A CB    1 
ATOM   68   C CG1   . VAL A 1 38  ? 149.433 129.985 169.776 1.00 34.50  ? 38  VAL A CG1   1 
ATOM   69   C CG2   . VAL A 1 38  ? 151.676 130.338 170.811 1.00 34.50  ? 38  VAL A CG2   1 
ATOM   70   N N     . ARG A 1 39  ? 147.982 127.942 172.198 1.00 39.24  ? 39  ARG A N     1 
ATOM   71   C CA    . ARG A 1 39  ? 146.601 127.481 172.151 1.00 39.24  ? 39  ARG A CA    1 
ATOM   72   C C     . ARG A 1 39  ? 145.839 127.808 173.427 1.00 39.24  ? 39  ARG A C     1 
ATOM   73   O O     . ARG A 1 39  ? 144.608 127.902 173.392 1.00 39.24  ? 39  ARG A O     1 
ATOM   74   C CB    . ARG A 1 39  ? 146.564 125.976 171.882 1.00 39.24  ? 39  ARG A CB    1 
ATOM   75   C CG    . ARG A 1 39  ? 145.174 125.411 171.662 1.00 39.24  ? 39  ARG A CG    1 
ATOM   76   C CD    . ARG A 1 39  ? 144.489 126.099 170.498 1.00 39.24  ? 39  ARG A CD    1 
ATOM   77   N NE    . ARG A 1 39  ? 143.231 125.451 170.152 1.00 39.24  ? 39  ARG A NE    1 
ATOM   78   C CZ    . ARG A 1 39  ? 142.056 125.774 170.674 1.00 39.24  ? 39  ARG A CZ    1 
ATOM   79   N NH1   . ARG A 1 39  ? 141.943 126.731 171.579 1.00 39.24  ? 39  ARG A NH1   1 
ATOM   80   N NH2   . ARG A 1 39  ? 140.969 125.119 170.279 1.00 39.24  ? 39  ARG A NH2   1 
ATOM   81   N N     . SER A 1 40  ? 146.538 127.999 174.548 1.00 35.98  ? 40  SER A N     1 
ATOM   82   C CA    . SER A 1 40  ? 145.865 128.398 175.778 1.00 35.98  ? 40  SER A CA    1 
ATOM   83   C C     . SER A 1 40  ? 145.279 129.803 175.704 1.00 35.98  ? 40  SER A C     1 
ATOM   84   O O     . SER A 1 40  ? 144.518 130.183 176.599 1.00 35.98  ? 40  SER A O     1 
ATOM   85   C CB    . SER A 1 40  ? 146.831 128.305 176.960 1.00 35.98  ? 40  SER A CB    1 
ATOM   86   O OG    . SER A 1 40  ? 147.880 129.248 176.833 1.00 35.98  ? 40  SER A OG    1 
ATOM   87   N N     . VAL A 1 41  ? 145.617 130.578 174.674 1.00 30.93  ? 41  VAL A N     1 
ATOM   88   C CA    . VAL A 1 41  ? 145.109 131.943 174.559 1.00 30.93  ? 41  VAL A CA    1 
ATOM   89   C C     . VAL A 1 41  ? 143.689 131.950 174.005 1.00 30.93  ? 41  VAL A C     1 
ATOM   90   O O     . VAL A 1 41  ? 142.754 132.434 174.652 1.00 30.93  ? 41  VAL A O     1 
ATOM   91   C CB    . VAL A 1 41  ? 146.053 132.793 173.689 1.00 30.93  ? 41  VAL A CB    1 
ATOM   92   C CG1   . VAL A 1 41  ? 145.332 134.023 173.176 1.00 30.93  ? 41  VAL A CG1   1 
ATOM   93   C CG2   . VAL A 1 41  ? 147.283 133.189 174.483 1.00 30.93  ? 41  VAL A CG2   1 
ATOM   94   N N     . GLY A 1 42  ? 143.507 131.418 172.799 1.00 35.56  ? 42  GLY A N     1 
ATOM   95   C CA    . GLY A 1 42  ? 142.216 131.485 172.151 1.00 35.56  ? 42  GLY A CA    1 
ATOM   96   C C     . GLY A 1 42  ? 141.247 130.427 172.634 1.00 35.56  ? 42  GLY A C     1 
ATOM   97   O O     . GLY A 1 42  ? 141.612 129.445 173.278 1.00 35.56  ? 42  GLY A O     1 
ATOM   98   N N     . GLU A 1 43  ? 139.974 130.644 172.307 1.00 52.39  ? 43  GLU A N     1 
ATOM   99   C CA    . GLU A 1 43  ? 138.921 129.681 172.598 1.00 52.39  ? 43  GLU A CA    1 
ATOM   100  C C     . GLU A 1 43  ? 138.501 128.868 171.387 1.00 52.39  ? 43  GLU A C     1 
ATOM   101  O O     . GLU A 1 43  ? 138.047 127.734 171.549 1.00 52.39  ? 43  GLU A O     1 
ATOM   102  C CB    . GLU A 1 43  ? 137.686 130.388 173.173 1.00 52.39  ? 43  GLU A CB    1 
ATOM   103  C CG    . GLU A 1 43  ? 136.930 131.248 172.172 1.00 52.39  ? 43  GLU A CG    1 
ATOM   104  C CD    . GLU A 1 43  ? 135.507 131.536 172.607 1.00 52.39  ? 43  GLU A CD    1 
ATOM   105  O OE1   . GLU A 1 43  ? 134.959 130.752 173.409 1.00 52.39  ? 43  GLU A OE1   1 
ATOM   106  O OE2   . GLU A 1 43  ? 134.935 132.545 172.143 1.00 52.39  ? 43  GLU A OE2   1 
ATOM   107  N N     . GLU A 1 44  ? 138.639 129.418 170.183 1.00 55.58  ? 44  GLU A N     1 
ATOM   108  C CA    . GLU A 1 44  ? 138.347 128.704 168.945 1.00 55.58  ? 44  GLU A CA    1 
ATOM   109  C C     . GLU A 1 44  ? 139.481 128.992 167.974 1.00 55.58  ? 44  GLU A C     1 
ATOM   110  O O     . GLU A 1 44  ? 139.529 130.069 167.370 1.00 55.58  ? 44  GLU A O     1 
ATOM   111  C CB    . GLU A 1 44  ? 136.998 129.126 168.360 1.00 55.58  ? 44  GLU A CB    1 
ATOM   112  C CG    . GLU A 1 44  ? 136.781 128.686 166.921 1.00 55.58  ? 44  GLU A CG    1 
ATOM   113  C CD    . GLU A 1 44  ? 135.401 129.036 166.406 1.00 55.58  ? 44  GLU A CD    1 
ATOM   114  O OE1   . GLU A 1 44  ? 134.406 128.590 167.015 1.00 55.58  ? 44  GLU A OE1   1 
ATOM   115  O OE2   . GLU A 1 44  ? 135.311 129.756 165.390 1.00 55.58  ? 44  GLU A OE2   1 
ATOM   116  N N     . CYS A 1 45  ? 140.401 128.043 167.839 1.00 57.37  ? 45  CYS A N     1 
ATOM   117  C CA    . CYS A 1 45  ? 141.548 128.175 166.949 1.00 57.37  ? 45  CYS A CA    1 
ATOM   118  C C     . CYS A 1 45  ? 141.330 127.262 165.751 1.00 57.37  ? 45  CYS A C     1 
ATOM   119  O O     . CYS A 1 45  ? 141.420 126.036 165.874 1.00 57.37  ? 45  CYS A O     1 
ATOM   120  C CB    . CYS A 1 45  ? 142.847 127.829 167.672 1.00 57.37  ? 45  CYS A CB    1 
ATOM   121  S SG    . CYS A 1 45  ? 144.324 128.039 166.659 1.00 57.37  ? 45  CYS A SG    1 
ATOM   122  N N     . ILE A 1 46  ? 141.041 127.856 164.601 1.00 56.81  ? 46  ILE A N     1 
ATOM   123  C CA    . ILE A 1 46  ? 140.858 127.083 163.381 1.00 56.81  ? 46  ILE A CA    1 
ATOM   124  C C     . ILE A 1 46  ? 142.220 126.625 162.878 1.00 56.81  ? 46  ILE A C     1 
ATOM   125  O O     . ILE A 1 46  ? 143.213 127.361 162.960 1.00 56.81  ? 46  ILE A O     1 
ATOM   126  C CB    . ILE A 1 46  ? 140.098 127.904 162.323 1.00 56.81  ? 46  ILE A CB    1 
ATOM   127  C CG1   . ILE A 1 46  ? 139.681 127.016 161.149 1.00 56.81  ? 46  ILE A CG1   1 
ATOM   128  C CG2   . ILE A 1 46  ? 140.930 129.076 161.839 1.00 56.81  ? 46  ILE A CG2   1 
ATOM   129  C CD1   . ILE A 1 46  ? 138.665 127.657 160.229 1.00 56.81  ? 46  ILE A CD1   1 
ATOM   130  N N     . GLN A 1 47  ? 142.274 125.386 162.387 1.00 58.71  ? 47  GLN A N     1 
ATOM   131  C CA    . GLN A 1 47  ? 143.507 124.765 161.906 1.00 58.71  ? 47  GLN A CA    1 
ATOM   132  C C     . GLN A 1 47  ? 144.570 124.725 163.008 1.00 58.71  ? 47  GLN A C     1 
ATOM   133  O O     . GLN A 1 47  ? 145.646 125.319 162.906 1.00 58.71  ? 47  GLN A O     1 
ATOM   134  C CB    . GLN A 1 47  ? 144.025 125.478 160.653 1.00 58.71  ? 47  GLN A CB    1 
ATOM   135  C CG    . GLN A 1 47  ? 143.049 125.468 159.488 1.00 58.71  ? 47  GLN A CG    1 
ATOM   136  C CD    . GLN A 1 47  ? 142.547 124.076 159.157 1.00 58.71  ? 47  GLN A CD    1 
ATOM   137  O OE1   . GLN A 1 47  ? 141.341 123.835 159.109 1.00 58.71  ? 47  GLN A OE1   1 
ATOM   138  N NE2   . GLN A 1 47  ? 143.471 123.153 158.924 1.00 58.71  ? 47  GLN A NE2   1 
ATOM   139  N N     . GLU A 1 48  ? 144.233 124.009 164.083 1.00 52.50  ? 48  GLU A N     1 
ATOM   140  C CA    . GLU A 1 48  ? 145.198 123.758 165.148 1.00 52.50  ? 48  GLU A CA    1 
ATOM   141  C C     . GLU A 1 48  ? 146.424 123.023 164.619 1.00 52.50  ? 48  GLU A C     1 
ATOM   142  O O     . GLU A 1 48  ? 147.542 123.227 165.113 1.00 52.50  ? 48  GLU A O     1 
ATOM   143  C CB    . GLU A 1 48  ? 144.525 122.960 166.265 1.00 52.50  ? 48  GLU A CB    1 
ATOM   144  C CG    . GLU A 1 48  ? 145.288 122.906 167.570 1.00 52.50  ? 48  GLU A CG    1 
ATOM   145  C CD    . GLU A 1 48  ? 144.519 122.173 168.652 1.00 52.50  ? 48  GLU A CD    1 
ATOM   146  O OE1   . GLU A 1 48  ? 143.441 121.623 168.344 1.00 52.50  ? 48  GLU A OE1   1 
ATOM   147  O OE2   . GLU A 1 48  ? 144.983 122.151 169.810 1.00 52.50  ? 48  GLU A OE2   1 
ATOM   148  N N     . ASP A 1 49  ? 146.231 122.168 163.612 1.00 50.92  ? 49  ASP A N     1 
ATOM   149  C CA    . ASP A 1 49  ? 147.361 121.529 162.949 1.00 50.92  ? 49  ASP A CA    1 
ATOM   150  C C     . ASP A 1 49  ? 148.271 122.571 162.314 1.00 50.92  ? 49  ASP A C     1 
ATOM   151  O O     . ASP A 1 49  ? 149.500 122.489 162.420 1.00 50.92  ? 49  ASP A O     1 
ATOM   152  C CB    . ASP A 1 49  ? 146.854 120.540 161.899 1.00 50.92  ? 49  ASP A CB    1 
ATOM   153  C CG    . ASP A 1 49  ? 145.824 119.578 162.456 1.00 50.92  ? 49  ASP A CG    1 
ATOM   154  O OD1   . ASP A 1 49  ? 145.934 119.208 163.644 1.00 50.92  ? 49  ASP A OD1   1 
ATOM   155  O OD2   . ASP A 1 49  ? 144.899 119.196 161.707 1.00 50.92  ? 49  ASP A OD2   1 
ATOM   156  N N     . GLU A 1 50  ? 147.680 123.568 161.650 1.00 52.24  ? 50  GLU A N     1 
ATOM   157  C CA    . GLU A 1 50  ? 148.478 124.654 161.093 1.00 52.24  ? 50  GLU A CA    1 
ATOM   158  C C     . GLU A 1 50  ? 149.158 125.464 162.187 1.00 52.24  ? 50  GLU A C     1 
ATOM   159  O O     . GLU A 1 50  ? 150.268 125.961 161.982 1.00 52.24  ? 50  GLU A O     1 
ATOM   160  C CB    . GLU A 1 50  ? 147.614 125.565 160.221 1.00 52.24  ? 50  GLU A CB    1 
ATOM   161  C CG    . GLU A 1 50  ? 147.239 124.967 158.877 1.00 52.24  ? 50  GLU A CG    1 
ATOM   162  C CD    . GLU A 1 50  ? 146.323 125.869 158.075 1.00 52.24  ? 50  GLU A CD    1 
ATOM   163  O OE1   . GLU A 1 50  ? 145.989 126.967 158.567 1.00 52.24  ? 50  GLU A OE1   1 
ATOM   164  O OE2   . GLU A 1 50  ? 145.936 125.480 156.953 1.00 52.24  ? 50  GLU A OE2   1 
ATOM   165  N N     . LEU A 1 51  ? 148.514 125.612 163.347 1.00 45.54  ? 51  LEU A N     1 
ATOM   166  C CA    . LEU A 1 51  ? 149.150 126.317 164.457 1.00 45.54  ? 51  LEU A CA    1 
ATOM   167  C C     . LEU A 1 51  ? 150.407 125.588 164.916 1.00 45.54  ? 51  LEU A C     1 
ATOM   168  O O     . LEU A 1 51  ? 151.466 126.202 165.109 1.00 45.54  ? 51  LEU A O     1 
ATOM   169  C CB    . LEU A 1 51  ? 148.165 126.470 165.616 1.00 45.54  ? 51  LEU A CB    1 
ATOM   170  C CG    . LEU A 1 51  ? 148.696 127.251 166.818 1.00 45.54  ? 51  LEU A CG    1 
ATOM   171  C CD1   . LEU A 1 51  ? 149.228 128.600 166.371 1.00 45.54  ? 51  LEU A CD1   1 
ATOM   172  C CD2   . LEU A 1 51  ? 147.619 127.419 167.872 1.00 45.54  ? 51  LEU A CD2   1 
ATOM   173  N N     . LEU A 1 52  ? 150.305 124.269 165.089 1.00 43.93  ? 52  LEU A N     1 
ATOM   174  C CA    . LEU A 1 52  ? 151.476 123.484 165.470 1.00 43.93  ? 52  LEU A CA    1 
ATOM   175  C C     . LEU A 1 52  ? 152.552 123.541 164.392 1.00 43.93  ? 52  LEU A C     1 
ATOM   176  O O     . LEU A 1 52  ? 153.744 123.684 164.697 1.00 43.93  ? 52  LEU A O     1 
ATOM   177  C CB    . LEU A 1 52  ? 151.072 122.036 165.749 1.00 43.93  ? 52  LEU A CB    1 
ATOM   178  C CG    . LEU A 1 52  ? 152.198 121.094 166.178 1.00 43.93  ? 52  LEU A CG    1 
ATOM   179  C CD1   . LEU A 1 52  ? 152.923 121.635 167.398 1.00 43.93  ? 52  LEU A CD1   1 
ATOM   180  C CD2   . LEU A 1 52  ? 151.650 119.704 166.454 1.00 43.93  ? 52  LEU A CD2   1 
ATOM   181  N N     . ASN A 1 53  ? 152.148 123.447 163.123 1.00 47.58  ? 53  ASN A N     1 
ATOM   182  C CA    . ASN A 1 53  ? 153.112 123.485 162.028 1.00 47.58  ? 53  ASN A CA    1 
ATOM   183  C C     . ASN A 1 53  ? 153.845 124.821 161.991 1.00 47.58  ? 53  ASN A C     1 
ATOM   184  O O     . ASN A 1 53  ? 155.064 124.866 161.782 1.00 47.58  ? 53  ASN A O     1 
ATOM   185  C CB    . ASN A 1 53  ? 152.393 123.219 160.705 1.00 47.58  ? 53  ASN A CB    1 
ATOM   186  C CG    . ASN A 1 53  ? 153.340 122.828 159.589 1.00 47.58  ? 53  ASN A CG    1 
ATOM   187  O OD1   . ASN A 1 53  ? 154.529 123.137 159.628 1.00 47.58  ? 53  ASN A OD1   1 
ATOM   188  N ND2   . ASN A 1 53  ? 152.812 122.142 158.582 1.00 47.58  ? 53  ASN A ND2   1 
ATOM   189  N N     . LEU A 1 54  ? 153.116 125.920 162.191 1.00 46.01  ? 54  LEU A N     1 
ATOM   190  C CA    . LEU A 1 54  ? 153.735 127.239 162.233 1.00 46.01  ? 54  LEU A CA    1 
ATOM   191  C C     . LEU A 1 54  ? 154.704 127.358 163.397 1.00 46.01  ? 54  LEU A C     1 
ATOM   192  O O     . LEU A 1 54  ? 155.837 127.823 163.232 1.00 46.01  ? 54  LEU A O     1 
ATOM   193  C CB    . LEU A 1 54  ? 152.661 128.318 162.336 1.00 46.01  ? 54  LEU A CB    1 
ATOM   194  C CG    . LEU A 1 54  ? 153.211 129.742 162.325 1.00 46.01  ? 54  LEU A CG    1 
ATOM   195  C CD1   . LEU A 1 54  ? 153.919 130.050 161.013 1.00 46.01  ? 54  LEU A CD1   1 
ATOM   196  C CD2   . LEU A 1 54  ? 152.111 130.736 162.605 1.00 46.01  ? 54  LEU A CD2   1 
ATOM   197  N N     . LEU A 1 55  ? 154.272 126.957 164.594 1.00 45.06  ? 55  LEU A N     1 
ATOM   198  C CA    . LEU A 1 55  ? 155.145 127.083 165.753 1.00 45.06  ? 55  LEU A CA    1 
ATOM   199  C C     . LEU A 1 55  ? 156.357 126.168 165.664 1.00 45.06  ? 55  LEU A C     1 
ATOM   200  O O     . LEU A 1 55  ? 157.354 126.412 166.352 1.00 45.06  ? 55  LEU A O     1 
ATOM   201  C CB    . LEU A 1 55  ? 154.358 126.815 167.033 1.00 45.06  ? 55  LEU A CB    1 
ATOM   202  C CG    . LEU A 1 55  ? 153.373 127.940 167.348 1.00 45.06  ? 55  LEU A CG    1 
ATOM   203  C CD1   . LEU A 1 55  ? 152.181 127.418 168.117 1.00 45.06  ? 55  LEU A CD1   1 
ATOM   204  C CD2   . LEU A 1 55  ? 154.070 129.048 168.120 1.00 45.06  ? 55  LEU A CD2   1 
ATOM   205  N N     . THR A 1 56  ? 156.299 125.124 164.834 1.00 48.71  ? 56  THR A N     1 
ATOM   206  C CA    . THR A 1 56  ? 157.491 124.317 164.597 1.00 48.71  ? 56  THR A CA    1 
ATOM   207  C C     . THR A 1 56  ? 158.411 124.975 163.573 1.00 48.71  ? 56  THR A C     1 
ATOM   208  O O     . THR A 1 56  ? 159.612 125.135 163.819 1.00 48.71  ? 56  THR A O     1 
ATOM   209  C CB    . THR A 1 56  ? 157.099 122.910 164.142 1.00 48.71  ? 56  THR A CB    1 
ATOM   210  O OG1   . THR A 1 56  ? 156.165 122.997 163.059 1.00 48.71  ? 56  THR A OG1   1 
ATOM   211  C CG2   . THR A 1 56  ? 156.478 122.131 165.291 1.00 48.71  ? 56  THR A CG2   1 
ATOM   212  N N     . LYS A 1 57  ? 157.867 125.363 162.415 1.00 49.51  ? 57  LYS A N     1 
ATOM   213  C CA    . LYS A 1 57  ? 158.709 125.895 161.344 1.00 49.51  ? 57  LYS A CA    1 
ATOM   214  C C     . LYS A 1 57  ? 159.319 127.241 161.717 1.00 49.51  ? 57  LYS A C     1 
ATOM   215  O O     . LYS A 1 57  ? 160.535 127.434 161.604 1.00 49.51  ? 57  LYS A O     1 
ATOM   216  C CB    . LYS A 1 57  ? 157.906 126.028 160.049 1.00 49.51  ? 57  LYS A CB    1 
ATOM   217  C CG    . LYS A 1 57  ? 157.417 124.722 159.459 1.00 49.51  ? 57  LYS A CG    1 
ATOM   218  C CD    . LYS A 1 57  ? 156.601 124.980 158.201 1.00 49.51  ? 57  LYS A CD    1 
ATOM   219  C CE    . LYS A 1 57  ? 156.901 123.951 157.126 1.00 49.51  ? 57  LYS A CE    1 
ATOM   220  N NZ    . LYS A 1 57  ? 156.764 122.561 157.641 1.00 49.51  ? 57  LYS A NZ    1 
ATOM   221  N N     . LYS A 1 58  ? 158.495 128.183 162.165 1.00 46.21  ? 58  LYS A N     1 
ATOM   222  C CA    . LYS A 1 58  ? 159.024 129.529 162.330 1.00 46.21  ? 58  LYS A CA    1 
ATOM   223  C C     . LYS A 1 58  ? 159.491 129.762 163.760 1.00 46.21  ? 58  LYS A C     1 
ATOM   224  O O     . LYS A 1 58  ? 158.821 129.341 164.710 1.00 46.21  ? 58  LYS A O     1 
ATOM   225  C CB    . LYS A 1 58  ? 157.965 130.572 161.969 1.00 46.21  ? 58  LYS A CB    1 
ATOM   226  C CG    . LYS A 1 58  ? 158.517 131.814 161.286 1.00 46.21  ? 58  LYS A CG    1 
ATOM   227  C CD    . LYS A 1 58  ? 157.421 132.597 160.581 1.00 46.21  ? 58  LYS A CD    1 
ATOM   228  C CE    . LYS A 1 58  ? 157.752 134.081 160.524 1.00 46.21  ? 58  LYS A CE    1 
ATOM   229  N NZ    . LYS A 1 58  ? 156.655 134.874 159.904 1.00 46.21  ? 58  LYS A NZ    1 
ATOM   230  N N     . PRO A 1 59  ? 160.638 130.425 163.938 1.00 44.89  ? 59  PRO A N     1 
ATOM   231  C CA    . PRO A 1 59  ? 161.104 130.725 165.299 1.00 44.89  ? 59  PRO A CA    1 
ATOM   232  C C     . PRO A 1 59  ? 160.407 131.910 165.939 1.00 44.89  ? 59  PRO A C     1 
ATOM   233  O O     . PRO A 1 59  ? 160.469 132.048 167.168 1.00 44.89  ? 59  PRO A O     1 
ATOM   234  C CB    . PRO A 1 59  ? 162.598 131.009 165.101 1.00 44.89  ? 59  PRO A CB    1 
ATOM   235  C CG    . PRO A 1 59  ? 162.693 131.532 163.705 1.00 44.89  ? 59  PRO A CG    1 
ATOM   236  C CD    . PRO A 1 59  ? 161.571 130.912 162.907 1.00 44.89  ? 59  PRO A CD    1 
ATOM   237  N N     . GLU A 1 60  ? 159.753 132.768 165.158 1.00 41.14  ? 60  GLU A N     1 
ATOM   238  C CA    . GLU A 1 60  ? 159.077 133.934 165.710 1.00 41.14  ? 60  GLU A CA    1 
ATOM   239  C C     . GLU A 1 60  ? 157.925 134.357 164.807 1.00 41.14  ? 60  GLU A C     1 
ATOM   240  O O     . GLU A 1 60  ? 158.072 135.291 164.008 1.00 41.14  ? 60  GLU A O     1 
ATOM   241  C CB    . GLU A 1 60  ? 160.063 135.088 165.894 1.00 41.14  ? 60  GLU A CB    1 
ATOM   242  C CG    . GLU A 1 60  ? 159.502 136.273 166.663 1.00 41.14  ? 60  GLU A CG    1 
ATOM   243  C CD    . GLU A 1 60  ? 160.540 137.346 166.916 1.00 41.14  ? 60  GLU A CD    1 
ATOM   244  O OE1   . GLU A 1 60  ? 161.700 137.162 166.492 1.00 41.14  ? 60  GLU A OE1   1 
ATOM   245  O OE2   . GLU A 1 60  ? 160.198 138.375 167.537 1.00 41.14  ? 60  GLU A OE2   1 
ATOM   246  N N     . PRO A 1 61  ? 156.775 133.694 164.889 1.00 40.66  ? 61  PRO A N     1 
ATOM   247  C CA    . PRO A 1 61  ? 155.623 134.120 164.090 1.00 40.66  ? 61  PRO A CA    1 
ATOM   248  C C     . PRO A 1 61  ? 155.079 135.456 164.573 1.00 40.66  ? 61  PRO A C     1 
ATOM   249  O O     . PRO A 1 61  ? 155.240 135.849 165.731 1.00 40.66  ? 61  PRO A O     1 
ATOM   250  C CB    . PRO A 1 61  ? 154.609 132.992 164.299 1.00 40.66  ? 61  PRO A CB    1 
ATOM   251  C CG    . PRO A 1 61  ? 154.959 132.431 165.619 1.00 40.66  ? 61  PRO A CG    1 
ATOM   252  C CD    . PRO A 1 61  ? 156.456 132.533 165.735 1.00 40.66  ? 61  PRO A CD    1 
ATOM   253  N N     . VAL A 1 62  ? 154.427 136.161 163.653 1.00 40.27  ? 62  VAL A N     1 
ATOM   254  C CA    . VAL A 1 62  ? 153.950 137.521 163.882 1.00 40.27  ? 62  VAL A CA    1 
ATOM   255  C C     . VAL A 1 62  ? 152.463 137.480 164.200 1.00 40.27  ? 62  VAL A C     1 
ATOM   256  O O     . VAL A 1 62  ? 151.685 136.831 163.490 1.00 40.27  ? 62  VAL A O     1 
ATOM   257  C CB    . VAL A 1 62  ? 154.226 138.414 162.662 1.00 40.27  ? 62  VAL A CB    1 
ATOM   258  C CG1   . VAL A 1 62  ? 153.693 139.811 162.900 1.00 40.27  ? 62  VAL A CG1   1 
ATOM   259  C CG2   . VAL A 1 62  ? 155.713 138.452 162.366 1.00 40.27  ? 62  VAL A CG2   1 
ATOM   260  N N     . CYS A 1 63  ? 152.066 138.179 165.260 1.00 36.95  ? 63  CYS A N     1 
ATOM   261  C CA    . CYS A 1 63  ? 150.685 138.219 165.714 1.00 36.95  ? 63  CYS A CA    1 
ATOM   262  C C     . CYS A 1 63  ? 150.200 139.661 165.794 1.00 36.95  ? 63  CYS A C     1 
ATOM   263  O O     . CYS A 1 63  ? 150.995 140.602 165.818 1.00 36.95  ? 63  CYS A O     1 
ATOM   264  C CB    . CYS A 1 63  ? 150.529 137.557 167.084 1.00 36.95  ? 63  CYS A CB    1 
ATOM   265  S SG    . CYS A 1 63  ? 148.871 137.731 167.760 1.00 36.95  ? 63  CYS A SG    1 
ATOM   266  N N     . TYR A 1 64  ? 148.881 139.837 165.827 1.00 40.66  ? 64  TYR A N     1 
ATOM   267  C CA    . TYR A 1 64  ? 148.329 141.163 166.063 1.00 40.66  ? 64  TYR A CA    1 
ATOM   268  C C     . TYR A 1 64  ? 147.103 140.998 166.949 1.00 40.66  ? 64  TYR A C     1 
ATOM   269  O O     . TYR A 1 64  ? 146.639 139.883 167.194 1.00 40.66  ? 64  TYR A O     1 
ATOM   270  C CB    . TYR A 1 64  ? 147.916 141.878 164.770 1.00 40.66  ? 64  TYR A CB    1 
ATOM   271  C CG    . TYR A 1 64  ? 146.784 141.196 164.055 1.00 40.66  ? 64  TYR A CG    1 
ATOM   272  C CD1   . TYR A 1 64  ? 147.004 140.216 163.113 1.00 40.66  ? 64  TYR A CD1   1 
ATOM   273  C CD2   . TYR A 1 64  ? 145.474 141.549 164.344 1.00 40.66  ? 64  TYR A CD2   1 
ATOM   274  C CE1   . TYR A 1 64  ? 145.951 139.605 162.485 1.00 40.66  ? 64  TYR A CE1   1 
ATOM   275  C CE2   . TYR A 1 64  ? 144.426 140.947 163.732 1.00 40.66  ? 64  TYR A CE2   1 
ATOM   276  C CZ    . TYR A 1 64  ? 144.662 139.978 162.801 1.00 40.66  ? 64  TYR A CZ    1 
ATOM   277  O OH    . TYR A 1 64  ? 143.584 139.389 162.197 1.00 40.66  ? 64  TYR A OH    1 
ATOM   278  N N     . ASP A 1 65  ? 146.572 142.121 167.424 1.00 42.16  ? 65  ASP A N     1 
ATOM   279  C CA    . ASP A 1 65  ? 145.243 142.144 168.017 1.00 42.16  ? 65  ASP A CA    1 
ATOM   280  C C     . ASP A 1 65  ? 144.464 143.334 167.473 1.00 42.16  ? 65  ASP A C     1 
ATOM   281  O O     . ASP A 1 65  ? 145.027 144.403 167.221 1.00 42.16  ? 65  ASP A O     1 
ATOM   282  C CB    . ASP A 1 65  ? 145.291 142.176 169.563 1.00 42.16  ? 65  ASP A CB    1 
ATOM   283  C CG    . ASP A 1 65  ? 146.080 143.350 170.115 1.00 42.16  ? 65  ASP A CG    1 
ATOM   284  O OD1   . ASP A 1 65  ? 146.682 144.106 169.327 1.00 42.16  ? 65  ASP A OD1   1 
ATOM   285  O OD2   . ASP A 1 65  ? 146.097 143.511 171.354 1.00 42.16  ? 65  ASP A OD2   1 
ATOM   286  N N     . GLY A 1 66  ? 143.166 143.127 167.264 1.00 48.71  ? 66  GLY A N     1 
ATOM   287  C CA    . GLY A 1 66  ? 142.299 144.192 166.793 1.00 48.71  ? 66  GLY A CA    1 
ATOM   288  C C     . GLY A 1 66  ? 141.778 145.013 167.952 1.00 48.71  ? 66  GLY A C     1 
ATOM   289  O O     . GLY A 1 66  ? 141.285 144.451 168.934 1.00 48.71  ? 66  GLY A O     1 
ATOM   290  N N     . PHE A 1 67  ? 141.872 146.339 167.860 1.00 52.01  ? 67  PHE A N     1 
ATOM   291  C CA    . PHE A 1 67  ? 141.621 147.171 169.033 1.00 52.01  ? 67  PHE A CA    1 
ATOM   292  C C     . PHE A 1 67  ? 141.251 148.579 168.585 1.00 52.01  ? 67  PHE A C     1 
ATOM   293  O O     . PHE A 1 67  ? 142.074 149.267 167.973 1.00 52.01  ? 67  PHE A O     1 
ATOM   294  C CB    . PHE A 1 67  ? 142.851 147.182 169.930 1.00 52.01  ? 67  PHE A CB    1 
ATOM   295  C CG    . PHE A 1 67  ? 142.673 147.962 171.188 1.00 52.01  ? 67  PHE A CG    1 
ATOM   296  C CD1   . PHE A 1 67  ? 141.927 147.440 172.227 1.00 52.01  ? 67  PHE A CD1   1 
ATOM   297  C CD2   . PHE A 1 67  ? 143.264 149.201 171.346 1.00 52.01  ? 67  PHE A CD2   1 
ATOM   298  C CE1   . PHE A 1 67  ? 141.757 148.142 173.395 1.00 52.01  ? 67  PHE A CE1   1 
ATOM   299  C CE2   . PHE A 1 67  ? 143.099 149.909 172.516 1.00 52.01  ? 67  PHE A CE2   1 
ATOM   300  C CZ    . PHE A 1 67  ? 142.346 149.374 173.541 1.00 52.01  ? 67  PHE A CZ    1 
ATOM   301  N N     . GLU A 1 68  ? 140.023 149.002 168.892 1.00 49.63  ? 68  GLU A N     1 
ATOM   302  C CA    . GLU A 1 68  ? 139.577 150.359 168.592 1.00 49.63  ? 68  GLU A CA    1 
ATOM   303  C C     . GLU A 1 68  ? 139.680 151.220 169.842 1.00 49.63  ? 68  GLU A C     1 
ATOM   304  O O     . GLU A 1 68  ? 138.997 150.932 170.834 1.00 49.63  ? 68  GLU A O     1 
ATOM   305  C CB    . GLU A 1 68  ? 138.143 150.360 168.087 1.00 49.63  ? 68  GLU A CB    1 
ATOM   306  C CG    . GLU A 1 68  ? 137.937 149.698 166.735 1.00 49.63  ? 68  GLU A CG    1 
ATOM   307  C CD    . GLU A 1 68  ? 137.811 148.191 166.835 1.00 49.63  ? 68  GLU A CD    1 
ATOM   308  O OE1   . GLU A 1 68  ? 137.821 147.668 167.969 1.00 49.63  ? 68  GLU A OE1   1 
ATOM   309  O OE2   . GLU A 1 68  ? 137.695 147.530 165.782 1.00 49.63  ? 68  GLU A OE2   1 
ATOM   310  N N     . PRO A 1 69  ? 140.496 152.275 169.848 1.00 45.87  ? 69  PRO A N     1 
ATOM   311  C CA    . PRO A 1 69  ? 140.629 153.118 171.044 1.00 45.87  ? 69  PRO A CA    1 
ATOM   312  C C     . PRO A 1 69  ? 139.491 154.118 171.136 1.00 45.87  ? 69  PRO A C     1 
ATOM   313  O O     . PRO A 1 69  ? 139.412 155.071 170.353 1.00 45.87  ? 69  PRO A O     1 
ATOM   314  C CB    . PRO A 1 69  ? 141.984 153.808 170.827 1.00 45.87  ? 69  PRO A CB    1 
ATOM   315  C CG    . PRO A 1 69  ? 142.169 153.833 169.336 1.00 45.87  ? 69  PRO A CG    1 
ATOM   316  C CD    . PRO A 1 69  ? 141.240 152.824 168.703 1.00 45.87  ? 69  PRO A CD    1 
ATOM   317  N N     . SER A 1 70  ? 138.603 153.913 172.107 1.00 66.21  ? 70  SER A N     1 
ATOM   318  C CA    . SER A 1 70  ? 137.444 154.785 172.268 1.00 66.21  ? 70  SER A CA    1 
ATOM   319  C C     . SER A 1 70  ? 137.149 154.933 173.754 1.00 66.21  ? 70  SER A C     1 
ATOM   320  O O     . SER A 1 70  ? 136.423 154.114 174.326 1.00 66.21  ? 70  SER A O     1 
ATOM   321  C CB    . SER A 1 70  ? 136.234 154.230 171.522 1.00 66.21  ? 70  SER A CB    1 
ATOM   322  O OG    . SER A 1 70  ? 135.828 152.988 172.069 1.00 66.21  ? 70  SER A OG    1 
ATOM   323  N N     . GLY A 1 71  ? 137.702 155.978 174.365 1.00 76.22  ? 71  GLY A N     1 
ATOM   324  C CA    . GLY A 1 71  ? 137.385 156.295 175.747 1.00 76.22  ? 71  GLY A CA    1 
ATOM   325  C C     . GLY A 1 71  ? 137.739 155.175 176.704 1.00 76.22  ? 71  GLY A C     1 
ATOM   326  O O     . GLY A 1 71  ? 138.804 154.554 176.617 1.00 76.22  ? 71  GLY A O     1 
ATOM   327  N N     . ARG A 1 72  ? 136.827 154.917 177.638 1.00 78.23  ? 72  ARG A N     1 
ATOM   328  C CA    . ARG A 1 72  ? 137.061 153.924 178.677 1.00 78.23  ? 72  ARG A CA    1 
ATOM   329  C C     . ARG A 1 72  ? 137.142 152.524 178.081 1.00 78.23  ? 72  ARG A C     1 
ATOM   330  O O     . ARG A 1 72  ? 136.394 152.174 177.165 1.00 78.23  ? 72  ARG A O     1 
ATOM   331  C CB    . ARG A 1 72  ? 135.950 153.998 179.724 1.00 78.23  ? 72  ARG A CB    1 
ATOM   332  C CG    . ARG A 1 72  ? 135.273 155.363 179.787 1.00 78.23  ? 72  ARG A CG    1 
ATOM   333  C CD    . ARG A 1 72  ? 134.142 155.402 180.802 1.00 78.23  ? 72  ARG A CD    1 
ATOM   334  N NE    . ARG A 1 72  ? 134.624 155.262 182.171 1.00 78.23  ? 72  ARG A NE    1 
ATOM   335  C CZ    . ARG A 1 72  ? 133.841 155.205 183.239 1.00 78.23  ? 72  ARG A CZ    1 
ATOM   336  N NH1   . ARG A 1 72  ? 132.524 155.279 183.135 1.00 78.23  ? 72  ARG A NH1   1 
ATOM   337  N NH2   . ARG A 1 72  ? 134.392 155.069 184.442 1.00 78.23  ? 72  ARG A NH2   1 
ATOM   338  N N     . MET A 1 73  ? 138.063 151.722 178.608 1.00 69.26  ? 73  MET A N     1 
ATOM   339  C CA    . MET A 1 73  ? 138.334 150.380 178.112 1.00 69.26  ? 73  MET A CA    1 
ATOM   340  C C     . MET A 1 73  ? 138.231 149.394 179.267 1.00 69.26  ? 73  MET A C     1 
ATOM   341  O O     . MET A 1 73  ? 138.871 149.579 180.307 1.00 69.26  ? 73  MET A O     1 
ATOM   342  C CB    . MET A 1 73  ? 139.702 150.353 177.414 1.00 69.26  ? 73  MET A CB    1 
ATOM   343  C CG    . MET A 1 73  ? 140.283 149.005 176.999 1.00 69.26  ? 73  MET A CG    1 
ATOM   344  S SD    . MET A 1 73  ? 140.960 148.020 178.342 1.00 69.26  ? 73  MET A SD    1 
ATOM   345  C CE    . MET A 1 73  ? 142.062 149.227 179.077 1.00 69.26  ? 73  MET A CE    1 
ATOM   346  N N     . HIS A 1 74  ? 137.428 148.349 179.076 1.00 66.37  ? 74  HIS A N     1 
ATOM   347  C CA    . HIS A 1 74  ? 136.945 147.518 180.166 1.00 66.37  ? 74  HIS A CA    1 
ATOM   348  C C     . HIS A 1 74  ? 137.886 146.350 180.455 1.00 66.37  ? 74  HIS A C     1 
ATOM   349  O O     . HIS A 1 74  ? 138.952 146.194 179.852 1.00 66.37  ? 74  HIS A O     1 
ATOM   350  C CB    . HIS A 1 74  ? 135.532 147.014 179.864 1.00 66.37  ? 74  HIS A CB    1 
ATOM   351  C CG    . HIS A 1 74  ? 135.362 146.470 178.481 1.00 66.37  ? 74  HIS A CG    1 
ATOM   352  N ND1   . HIS A 1 74  ? 135.924 145.279 178.075 1.00 66.37  ? 74  HIS A ND1   1 
ATOM   353  C CD2   . HIS A 1 74  ? 134.684 146.950 177.412 1.00 66.37  ? 74  HIS A CD2   1 
ATOM   354  C CE1   . HIS A 1 74  ? 135.602 145.051 176.814 1.00 66.37  ? 74  HIS A CE1   1 
ATOM   355  N NE2   . HIS A 1 74  ? 134.851 146.050 176.388 1.00 66.37  ? 74  HIS A NE2   1 
ATOM   356  N N     . ILE A 1 75  ? 137.456 145.511 181.401 1.00 62.24  ? 75  ILE A N     1 
ATOM   357  C CA    . ILE A 1 75  ? 138.310 144.454 181.934 1.00 62.24  ? 75  ILE A CA    1 
ATOM   358  C C     . ILE A 1 75  ? 138.643 143.431 180.854 1.00 62.24  ? 75  ILE A C     1 
ATOM   359  O O     . ILE A 1 75  ? 139.751 142.881 180.823 1.00 62.24  ? 75  ILE A O     1 
ATOM   360  C CB    . ILE A 1 75  ? 137.638 143.805 183.162 1.00 62.24  ? 75  ILE A CB    1 
ATOM   361  C CG1   . ILE A 1 75  ? 138.624 142.923 183.928 1.00 62.24  ? 75  ILE A CG1   1 
ATOM   362  C CG2   . ILE A 1 75  ? 136.386 143.026 182.771 1.00 62.24  ? 75  ILE A CG2   1 
ATOM   363  C CD1   . ILE A 1 75  ? 139.750 143.689 184.564 1.00 62.24  ? 75  ILE A CD1   1 
ATOM   364  N N     . ALA A 1 76  ? 137.697 143.165 179.947 1.00 56.25  ? 76  ALA A N     1 
ATOM   365  C CA    . ALA A 1 76  ? 137.936 142.184 178.893 1.00 56.25  ? 76  ALA A CA    1 
ATOM   366  C C     . ALA A 1 76  ? 139.062 142.625 177.968 1.00 56.25  ? 76  ALA A C     1 
ATOM   367  O O     . ALA A 1 76  ? 139.937 141.825 177.619 1.00 56.25  ? 76  ALA A O     1 
ATOM   368  C CB    . ALA A 1 76  ? 136.654 141.945 178.097 1.00 56.25  ? 76  ALA A CB    1 
ATOM   369  N N     . GLN A 1 77  ? 139.059 143.892 177.555 1.00 56.73  ? 77  GLN A N     1 
ATOM   370  C CA    . GLN A 1 77  ? 140.127 144.387 176.700 1.00 56.73  ? 77  GLN A CA    1 
ATOM   371  C C     . GLN A 1 77  ? 141.411 144.670 177.464 1.00 56.73  ? 77  GLN A C     1 
ATOM   372  O O     . GLN A 1 77  ? 142.475 144.755 176.843 1.00 56.73  ? 77  GLN A O     1 
ATOM   373  C CB    . GLN A 1 77  ? 139.680 145.653 175.963 1.00 56.73  ? 77  GLN A CB    1 
ATOM   374  C CG    . GLN A 1 77  ? 138.453 145.507 175.060 1.00 56.73  ? 77  GLN A CG    1 
ATOM   375  C CD    . GLN A 1 77  ? 138.615 144.471 173.955 1.00 56.73  ? 77  GLN A CD    1 
ATOM   376  O OE1   . GLN A 1 77  ? 138.802 143.281 174.211 1.00 56.73  ? 77  GLN A OE1   1 
ATOM   377  N NE2   . GLN A 1 77  ? 138.540 144.929 172.710 1.00 56.73  ? 77  GLN A NE2   1 
ATOM   378  N N     . GLY A 1 78  ? 141.345 144.861 178.777 1.00 51.04  ? 78  GLY A N     1 
ATOM   379  C CA    . GLY A 1 78  ? 142.577 145.028 179.522 1.00 51.04  ? 78  GLY A CA    1 
ATOM   380  C C     . GLY A 1 78  ? 143.277 143.739 179.906 1.00 51.04  ? 78  GLY A C     1 
ATOM   381  O O     . GLY A 1 78  ? 144.337 143.405 179.364 1.00 51.04  ? 78  GLY A O     1 
ATOM   382  N N     . VAL A 1 79  ? 142.652 142.971 180.799 1.00 51.09  ? 79  VAL A N     1 
ATOM   383  C CA    . VAL A 1 79  ? 143.361 141.876 181.452 1.00 51.09  ? 79  VAL A CA    1 
ATOM   384  C C     . VAL A 1 79  ? 143.422 140.646 180.557 1.00 51.09  ? 79  VAL A C     1 
ATOM   385  O O     . VAL A 1 79  ? 144.462 139.986 180.470 1.00 51.09  ? 79  VAL A O     1 
ATOM   386  C CB    . VAL A 1 79  ? 142.720 141.564 182.816 1.00 51.09  ? 79  VAL A CB    1 
ATOM   387  C CG1   . VAL A 1 79  ? 143.209 140.227 183.343 1.00 51.09  ? 79  VAL A CG1   1 
ATOM   388  C CG2   . VAL A 1 79  ? 143.058 142.665 183.805 1.00 51.09  ? 79  VAL A CG2   1 
ATOM   389  N N     . MET A 1 80  ? 142.325 140.313 179.877 1.00 48.94  ? 80  MET A N     1 
ATOM   390  C CA    . MET A 1 80  ? 142.366 139.190 178.947 1.00 48.94  ? 80  MET A CA    1 
ATOM   391  C C     . MET A 1 80  ? 143.372 139.445 177.832 1.00 48.94  ? 80  MET A C     1 
ATOM   392  O O     . MET A 1 80  ? 144.153 138.555 177.471 1.00 48.94  ? 80  MET A O     1 
ATOM   393  C CB    . MET A 1 80  ? 140.973 138.934 178.373 1.00 48.94  ? 80  MET A CB    1 
ATOM   394  C CG    . MET A 1 80  ? 140.719 137.493 177.979 1.00 48.94  ? 80  MET A CG    1 
ATOM   395  S SD    . MET A 1 80  ? 139.125 137.268 177.171 1.00 48.94  ? 80  MET A SD    1 
ATOM   396  C CE    . MET A 1 80  ? 139.406 135.728 176.301 1.00 48.94  ? 80  MET A CE    1 
ATOM   397  N N     . LYS A 1 81  ? 143.383 140.666 177.292 1.00 47.95  ? 81  LYS A N     1 
ATOM   398  C CA    . LYS A 1 81  ? 144.324 140.996 176.227 1.00 47.95  ? 81  LYS A CA    1 
ATOM   399  C C     . LYS A 1 81  ? 145.763 140.946 176.720 1.00 47.95  ? 81  LYS A C     1 
ATOM   400  O O     . LYS A 1 81  ? 146.642 140.425 176.023 1.00 47.95  ? 81  LYS A O     1 
ATOM   401  C CB    . LYS A 1 81  ? 144.008 142.374 175.650 1.00 47.95  ? 81  LYS A CB    1 
ATOM   402  C CG    . LYS A 1 81  ? 142.799 142.406 174.733 1.00 47.95  ? 81  LYS A CG    1 
ATOM   403  C CD    . LYS A 1 81  ? 143.081 141.745 173.399 1.00 47.95  ? 81  LYS A CD    1 
ATOM   404  C CE    . LYS A 1 81  ? 141.965 142.039 172.412 1.00 47.95  ? 81  LYS A CE    1 
ATOM   405  N NZ    . LYS A 1 81  ? 142.390 141.829 171.005 1.00 47.95  ? 81  LYS A NZ    1 
ATOM   406  N N     . THR A 1 82  ? 146.035 141.480 177.916 1.00 48.10  ? 82  THR A N     1 
ATOM   407  C CA    . THR A 1 82  ? 147.413 141.454 178.396 1.00 48.10  ? 82  THR A CA    1 
ATOM   408  C C     . THR A 1 82  ? 147.855 140.041 178.757 1.00 48.10  ? 82  THR A C     1 
ATOM   409  O O     . THR A 1 82  ? 149.025 139.700 178.566 1.00 48.10  ? 82  THR A O     1 
ATOM   410  C CB    . THR A 1 82  ? 147.600 142.411 179.578 1.00 48.10  ? 82  THR A CB    1 
ATOM   411  O OG1   . THR A 1 82  ? 149.000 142.574 179.841 1.00 48.10  ? 82  THR A OG1   1 
ATOM   412  C CG2   . THR A 1 82  ? 146.922 141.894 180.828 1.00 48.10  ? 82  THR A CG2   1 
ATOM   413  N N     . ILE A 1 83  ? 146.940 139.195 179.237 1.00 44.36  ? 83  ILE A N     1 
ATOM   414  C CA    . ILE A 1 83  ? 147.283 137.798 179.490 1.00 44.36  ? 83  ILE A CA    1 
ATOM   415  C C     . ILE A 1 83  ? 147.609 137.088 178.184 1.00 44.36  ? 83  ILE A C     1 
ATOM   416  O O     . ILE A 1 83  ? 148.592 136.341 178.092 1.00 44.36  ? 83  ILE A O     1 
ATOM   417  C CB    . ILE A 1 83  ? 146.142 137.098 180.252 1.00 44.36  ? 83  ILE A CB    1 
ATOM   418  C CG1   . ILE A 1 83  ? 146.249 137.387 181.750 1.00 44.36  ? 83  ILE A CG1   1 
ATOM   419  C CG2   . ILE A 1 83  ? 146.155 135.598 179.994 1.00 44.36  ? 83  ILE A CG2   1 
ATOM   420  C CD1   . ILE A 1 83  ? 145.002 137.036 182.528 1.00 44.36  ? 83  ILE A CD1   1 
ATOM   421  N N     . SER A 1 84  ? 146.793 137.314 177.151 1.00 40.38  ? 84  SER A N     1 
ATOM   422  C CA    . SER A 1 84  ? 147.053 136.698 175.854 1.00 40.38  ? 84  SER A CA    1 
ATOM   423  C C     . SER A 1 84  ? 148.388 137.157 175.281 1.00 40.38  ? 84  SER A C     1 
ATOM   424  O O     . SER A 1 84  ? 149.170 136.343 174.774 1.00 40.38  ? 84  SER A O     1 
ATOM   425  C CB    . SER A 1 84  ? 145.915 137.023 174.890 1.00 40.38  ? 84  SER A CB    1 
ATOM   426  O OG    . SER A 1 84  ? 144.696 136.454 175.335 1.00 40.38  ? 84  SER A OG    1 
ATOM   427  N N     . VAL A 1 85  ? 148.670 138.458 175.364 1.00 42.15  ? 85  VAL A N     1 
ATOM   428  C CA    . VAL A 1 85  ? 149.926 138.982 174.840 1.00 42.15  ? 85  VAL A CA    1 
ATOM   429  C C     . VAL A 1 85  ? 151.108 138.437 175.630 1.00 42.15  ? 85  VAL A C     1 
ATOM   430  O O     . VAL A 1 85  ? 152.154 138.112 175.057 1.00 42.15  ? 85  VAL A O     1 
ATOM   431  C CB    . VAL A 1 85  ? 149.901 140.520 174.837 1.00 42.15  ? 85  VAL A CB    1 
ATOM   432  C CG1   . VAL A 1 85  ? 151.269 141.066 174.499 1.00 42.15  ? 85  VAL A CG1   1 
ATOM   433  C CG2   . VAL A 1 85  ? 148.876 141.024 173.838 1.00 42.15  ? 85  VAL A CG2   1 
ATOM   434  N N     . ASN A 1 86  ? 150.969 138.329 176.954 1.00 42.67  ? 86  ASN A N     1 
ATOM   435  C CA    . ASN A 1 86  ? 152.049 137.780 177.765 1.00 42.67  ? 86  ASN A CA    1 
ATOM   436  C C     . ASN A 1 86  ? 152.314 136.323 177.416 1.00 42.67  ? 86  ASN A C     1 
ATOM   437  O O     . ASN A 1 86  ? 153.471 135.902 177.317 1.00 42.67  ? 86  ASN A O     1 
ATOM   438  C CB    . ASN A 1 86  ? 151.718 137.929 179.249 1.00 42.67  ? 86  ASN A CB    1 
ATOM   439  C CG    . ASN A 1 86  ? 152.354 139.158 179.862 1.00 42.67  ? 86  ASN A CG    1 
ATOM   440  O OD1   . ASN A 1 86  ? 152.605 140.149 179.176 1.00 42.67  ? 86  ASN A OD1   1 
ATOM   441  N ND2   . ASN A 1 86  ? 152.620 139.100 181.162 1.00 42.67  ? 86  ASN A ND2   1 
ATOM   442  N N     . LYS A 1 87  ? 151.255 135.537 177.214 1.00 39.22  ? 87  LYS A N     1 
ATOM   443  C CA    . LYS A 1 87  ? 151.449 134.149 176.808 1.00 39.22  ? 87  LYS A CA    1 
ATOM   444  C C     . LYS A 1 87  ? 152.138 134.065 175.452 1.00 39.22  ? 87  LYS A C     1 
ATOM   445  O O     . LYS A 1 87  ? 153.068 133.269 175.266 1.00 39.22  ? 87  LYS A O     1 
ATOM   446  C CB    . LYS A 1 87  ? 150.108 133.418 176.777 1.00 39.22  ? 87  LYS A CB    1 
ATOM   447  C CG    . LYS A 1 87  ? 149.675 132.861 178.120 1.00 39.22  ? 87  LYS A CG    1 
ATOM   448  C CD    . LYS A 1 87  ? 148.289 132.247 178.039 1.00 39.22  ? 87  LYS A CD    1 
ATOM   449  C CE    . LYS A 1 87  ? 147.758 131.907 179.420 1.00 39.22  ? 87  LYS A CE    1 
ATOM   450  N NZ    . LYS A 1 87  ? 146.407 131.288 179.354 1.00 39.22  ? 87  LYS A NZ    1 
ATOM   451  N N     . LEU A 1 88  ? 151.713 134.895 174.497 1.00 37.57  ? 88  LEU A N     1 
ATOM   452  C CA    . LEU A 1 88  ? 152.294 134.826 173.160 1.00 37.57  ? 88  LEU A CA    1 
ATOM   453  C C     . LEU A 1 88  ? 153.746 135.284 173.142 1.00 37.57  ? 88  LEU A C     1 
ATOM   454  O O     . LEU A 1 88  ? 154.556 134.731 172.391 1.00 37.57  ? 88  LEU A O     1 
ATOM   455  C CB    . LEU A 1 88  ? 151.462 135.647 172.179 1.00 37.57  ? 88  LEU A CB    1 
ATOM   456  C CG    . LEU A 1 88  ? 150.072 135.085 171.881 1.00 37.57  ? 88  LEU A CG    1 
ATOM   457  C CD1   . LEU A 1 88  ? 149.598 135.563 170.528 1.00 37.57  ? 88  LEU A CD1   1 
ATOM   458  C CD2   . LEU A 1 88  ? 150.064 133.567 171.942 1.00 37.57  ? 88  LEU A CD2   1 
ATOM   459  N N     . THR A 1 89  ? 154.099 136.287 173.948 1.00 41.54  ? 89  THR A N     1 
ATOM   460  C CA    . THR A 1 89  ? 155.493 136.709 174.011 1.00 41.54  ? 89  THR A CA    1 
ATOM   461  C C     . THR A 1 89  ? 156.343 135.744 174.827 1.00 41.54  ? 89  THR A C     1 
ATOM   462  O O     . THR A 1 89  ? 157.559 135.672 174.618 1.00 41.54  ? 89  THR A O     1 
ATOM   463  C CB    . THR A 1 89  ? 155.601 138.126 174.580 1.00 41.54  ? 89  THR A CB    1 
ATOM   464  O OG1   . THR A 1 89  ? 156.955 138.581 174.475 1.00 41.54  ? 89  THR A OG1   1 
ATOM   465  C CG2   . THR A 1 89  ? 155.181 138.155 176.034 1.00 41.54  ? 89  THR A CG2   1 
ATOM   466  N N     . SER A 1 90  ? 155.735 135.000 175.755 1.00 39.75  ? 90  SER A N     1 
ATOM   467  C CA    . SER A 1 90  ? 156.464 133.934 176.430 1.00 39.75  ? 90  SER A CA    1 
ATOM   468  C C     . SER A 1 90  ? 156.705 132.757 175.498 1.00 39.75  ? 90  SER A C     1 
ATOM   469  O O     . SER A 1 90  ? 157.698 132.038 175.651 1.00 39.75  ? 90  SER A O     1 
ATOM   470  C CB    . SER A 1 90  ? 155.705 133.483 177.677 1.00 39.75  ? 90  SER A CB    1 
ATOM   471  O OG    . SER A 1 90  ? 155.573 134.544 178.606 1.00 39.75  ? 90  SER A OG    1 
ATOM   472  N N     . ALA A 1 91  ? 155.813 132.546 174.532 1.00 35.76  ? 91  ALA A N     1 
ATOM   473  C CA    . ALA A 1 91  ? 156.003 131.519 173.517 1.00 35.76  ? 91  ALA A CA    1 
ATOM   474  C C     . ALA A 1 91  ? 156.953 131.955 172.407 1.00 35.76  ? 91  ALA A C     1 
ATOM   475  O O     . ALA A 1 91  ? 157.001 131.298 171.362 1.00 35.76  ? 91  ALA A O     1 
ATOM   476  C CB    . ALA A 1 91  ? 154.655 131.114 172.916 1.00 35.76  ? 91  ALA A CB    1 
ATOM   477  N N     . GLY A 1 92  ? 157.698 133.036 172.608 1.00 37.09  ? 92  GLY A N     1 
ATOM   478  C CA    . GLY A 1 92  ? 158.643 133.515 171.613 1.00 37.09  ? 92  GLY A CA    1 
ATOM   479  C C     . GLY A 1 92  ? 158.010 134.008 170.330 1.00 37.09  ? 92  GLY A C     1 
ATOM   480  O O     . GLY A 1 92  ? 158.601 133.853 169.254 1.00 37.09  ? 92  GLY A O     1 
ATOM   481  N N     . CYS A 1 93  ? 156.825 134.606 170.417 1.00 36.96  ? 93  CYS A N     1 
ATOM   482  C CA    . CYS A 1 93  ? 156.115 135.132 169.261 1.00 36.96  ? 93  CYS A CA    1 
ATOM   483  C C     . CYS A 1 93  ? 155.859 136.618 169.462 1.00 36.96  ? 93  CYS A C     1 
ATOM   484  O O     . CYS A 1 93  ? 155.484 137.048 170.558 1.00 36.96  ? 93  CYS A O     1 
ATOM   485  C CB    . CYS A 1 93  ? 154.789 134.398 169.043 1.00 36.96  ? 93  CYS A CB    1 
ATOM   486  S SG    . CYS A 1 93  ? 154.906 132.599 169.155 1.00 36.96  ? 93  CYS A SG    1 
ATOM   487  N N     . ARG A 1 94  ? 156.064 137.399 168.408 1.00 40.96  ? 94  ARG A N     1 
ATOM   488  C CA    . ARG A 1 94  ? 155.840 138.834 168.477 1.00 40.96  ? 94  ARG A CA    1 
ATOM   489  C C     . ARG A 1 94  ? 154.379 139.162 168.198 1.00 40.96  ? 94  ARG A C     1 
ATOM   490  O O     . ARG A 1 94  ? 153.696 138.465 167.443 1.00 40.96  ? 94  ARG A O     1 
ATOM   491  C CB    . ARG A 1 94  ? 156.740 139.579 167.490 1.00 40.96  ? 94  ARG A CB    1 
ATOM   492  C CG    . ARG A 1 94  ? 156.370 139.397 166.028 1.00 40.96  ? 94  ARG A CG    1 
ATOM   493  C CD    . ARG A 1 94  ? 157.176 140.335 165.143 1.00 40.96  ? 94  ARG A CD    1 
ATOM   494  N NE    . ARG A 1 94  ? 158.612 140.135 165.299 1.00 40.96  ? 94  ARG A NE    1 
ATOM   495  C CZ    . ARG A 1 94  ? 159.420 140.974 165.931 1.00 40.96  ? 94  ARG A CZ    1 
ATOM   496  N NH1   . ARG A 1 94  ? 158.966 142.088 166.482 1.00 40.96  ? 94  ARG A NH1   1 
ATOM   497  N NH2   . ARG A 1 94  ? 160.716 140.687 166.017 1.00 40.96  ? 94  ARG A NH2   1 
ATOM   498  N N     . VAL A 1 95  ? 153.904 140.234 168.826 1.00 37.01  ? 95  VAL A N     1 
ATOM   499  C CA    . VAL A 1 95  ? 152.537 140.709 168.661 1.00 37.01  ? 95  VAL A CA    1 
ATOM   500  C C     . VAL A 1 95  ? 152.578 142.168 168.233 1.00 37.01  ? 95  VAL A C     1 
ATOM   501  O O     . VAL A 1 95  ? 153.374 142.958 168.752 1.00 37.01  ? 95  VAL A O     1 
ATOM   502  C CB    . VAL A 1 95  ? 151.710 140.541 169.951 1.00 37.01  ? 95  VAL A CB    1 
ATOM   503  C CG1   . VAL A 1 95  ? 151.449 139.072 170.223 1.00 37.01  ? 95  VAL A CG1   1 
ATOM   504  C CG2   . VAL A 1 95  ? 152.430 141.175 171.123 1.00 37.01  ? 95  VAL A CG2   1 
ATOM   505  N N     . LYS A 1 96  ? 151.731 142.521 167.272 1.00 34.65  ? 96  LYS A N     1 
ATOM   506  C CA    . LYS A 1 96  ? 151.634 143.884 166.766 1.00 34.65  ? 96  LYS A CA    1 
ATOM   507  C C     . LYS A 1 96  ? 150.295 144.463 167.205 1.00 34.65  ? 96  LYS A C     1 
ATOM   508  O O     . LYS A 1 96  ? 149.243 144.061 166.699 1.00 34.65  ? 96  LYS A O     1 
ATOM   509  C CB    . LYS A 1 96  ? 151.771 143.913 165.247 1.00 34.65  ? 96  LYS A CB    1 
ATOM   510  C CG    . LYS A 1 96  ? 153.163 143.591 164.737 1.00 34.65  ? 96  LYS A CG    1 
ATOM   511  C CD    . LYS A 1 96  ? 153.142 143.320 163.244 1.00 34.65  ? 96  LYS A CD    1 
ATOM   512  C CE    . LYS A 1 96  ? 154.474 143.658 162.597 1.00 34.65  ? 96  LYS A CE    1 
ATOM   513  N NZ    . LYS A 1 96  ? 154.877 145.067 162.848 1.00 34.65  ? 96  LYS A NZ    1 
ATOM   514  N N     . ILE A 1 97  ? 150.332 145.412 168.137 1.00 33.08  ? 97  ILE A N     1 
ATOM   515  C CA    . ILE A 1 97  ? 149.105 146.064 168.577 1.00 33.08  ? 97  ILE A CA    1 
ATOM   516  C C     . ILE A 1 97  ? 148.630 146.983 167.461 1.00 33.08  ? 97  ILE A C     1 
ATOM   517  O O     . ILE A 1 97  ? 149.383 147.836 166.977 1.00 33.08  ? 97  ILE A O     1 
ATOM   518  C CB    . ILE A 1 97  ? 149.332 146.835 169.882 1.00 33.08  ? 97  ILE A CB    1 
ATOM   519  C CG1   . ILE A 1 97  ? 149.913 145.910 170.952 1.00 33.08  ? 97  ILE A CG1   1 
ATOM   520  C CG2   . ILE A 1 97  ? 148.032 147.440 170.372 1.00 33.08  ? 97  ILE A CG2   1 
ATOM   521  C CD1   . ILE A 1 97  ? 148.943 144.885 171.470 1.00 33.08  ? 97  ILE A CD1   1 
ATOM   522  N N     . TRP A 1 98  ? 147.381 146.809 167.041 1.00 32.17  ? 98  TRP A N     1 
ATOM   523  C CA    . TRP A 1 98  ? 146.835 147.511 165.881 1.00 32.17  ? 98  TRP A CA    1 
ATOM   524  C C     . TRP A 1 98  ? 145.844 148.565 166.371 1.00 32.17  ? 98  TRP A C     1 
ATOM   525  O O     . TRP A 1 98  ? 144.643 148.312 166.475 1.00 32.17  ? 98  TRP A O     1 
ATOM   526  C CB    . TRP A 1 98  ? 146.180 146.529 164.913 1.00 32.17  ? 98  TRP A CB    1 
ATOM   527  C CG    . TRP A 1 98  ? 145.949 147.101 163.553 1.00 32.17  ? 98  TRP A CG    1 
ATOM   528  C CD1   . TRP A 1 98  ? 144.769 147.148 162.873 1.00 32.17  ? 98  TRP A CD1   1 
ATOM   529  C CD2   . TRP A 1 98  ? 146.929 147.704 162.698 1.00 32.17  ? 98  TRP A CD2   1 
ATOM   530  N NE1   . TRP A 1 98  ? 144.950 147.748 161.650 1.00 32.17  ? 98  TRP A NE1   1 
ATOM   531  C CE2   . TRP A 1 98  ? 146.268 148.097 161.518 1.00 32.17  ? 98  TRP A CE2   1 
ATOM   532  C CE3   . TRP A 1 98  ? 148.300 147.950 162.816 1.00 32.17  ? 98  TRP A CE3   1 
ATOM   533  C CZ2   . TRP A 1 98  ? 146.930 148.723 160.467 1.00 32.17  ? 98  TRP A CZ2   1 
ATOM   534  C CZ3   . TRP A 1 98  ? 148.954 148.571 161.772 1.00 32.17  ? 98  TRP A CZ3   1 
ATOM   535  C CH2   . TRP A 1 98  ? 148.270 148.949 160.612 1.00 32.17  ? 98  TRP A CH2   1 
ATOM   536  N N     . ILE A 1 99  ? 146.360 149.757 166.663 1.00 34.21  ? 99  ILE A N     1 
ATOM   537  C CA    . ILE A 1 99  ? 145.527 150.873 167.101 1.00 34.21  ? 99  ILE A CA    1 
ATOM   538  C C     . ILE A 1 99  ? 144.674 151.318 165.918 1.00 34.21  ? 99  ILE A C     1 
ATOM   539  O O     . ILE A 1 99  ? 145.193 151.831 164.924 1.00 34.21  ? 99  ILE A O     1 
ATOM   540  C CB    . ILE A 1 99  ? 146.376 152.028 167.641 1.00 34.21  ? 99  ILE A CB    1 
ATOM   541  C CG1   . ILE A 1 99  ? 147.386 151.512 168.665 1.00 34.21  ? 99  ILE A CG1   1 
ATOM   542  C CG2   . ILE A 1 99  ? 145.492 153.084 168.267 1.00 34.21  ? 99  ILE A CG2   1 
ATOM   543  C CD1   . ILE A 1 99  ? 146.749 150.895 169.887 1.00 34.21  ? 99  ILE A CD1   1 
ATOM   544  N N     . ALA A 1 100 ? 143.364 151.123 166.022 1.00 36.27  ? 100 ALA A N     1 
ATOM   545  C CA    . ALA A 1 100 ? 142.440 151.389 164.920 1.00 36.27  ? 100 ALA A CA    1 
ATOM   546  C C     . ALA A 1 100 ? 141.870 152.804 165.013 1.00 36.27  ? 100 ALA A C     1 
ATOM   547  O O     . ALA A 1 100 ? 140.656 153.018 165.024 1.00 36.27  ? 100 ALA A O     1 
ATOM   548  C CB    . ALA A 1 100 ? 141.330 150.345 164.908 1.00 36.27  ? 100 ALA A CB    1 
ATOM   549  N N     . ASP A 1 101 ? 142.770 153.787 165.074 1.00 39.88  ? 101 ASP A N     1 
ATOM   550  C CA    . ASP A 1 101 ? 142.326 155.172 165.193 1.00 39.88  ? 101 ASP A CA    1 
ATOM   551  C C     . ASP A 1 101 ? 141.635 155.644 163.919 1.00 39.88  ? 101 ASP A C     1 
ATOM   552  O O     . ASP A 1 101 ? 140.673 156.417 163.979 1.00 39.88  ? 101 ASP A O     1 
ATOM   553  C CB    . ASP A 1 101 ? 143.506 156.080 165.542 1.00 39.88  ? 101 ASP A CB    1 
ATOM   554  C CG    . ASP A 1 101 ? 144.531 156.161 164.432 1.00 39.88  ? 101 ASP A CG    1 
ATOM   555  O OD1   . ASP A 1 101 ? 144.281 156.883 163.447 1.00 39.88  ? 101 ASP A OD1   1 
ATOM   556  O OD2   . ASP A 1 101 ? 145.588 155.508 164.546 1.00 39.88  ? 101 ASP A OD2   1 
ATOM   557  N N     . TRP A 1 102 ? 142.112 155.194 162.757 1.00 33.39  ? 102 TRP A N     1 
ATOM   558  C CA    . TRP A 1 102 ? 141.456 155.535 161.498 1.00 33.39  ? 102 TRP A CA    1 
ATOM   559  C C     . TRP A 1 102 ? 140.032 154.992 161.461 1.00 33.39  ? 102 TRP A C     1 
ATOM   560  O O     . TRP A 1 102 ? 139.093 155.695 161.061 1.00 33.39  ? 102 TRP A O     1 
ATOM   561  C CB    . TRP A 1 102 ? 142.279 154.982 160.334 1.00 33.39  ? 102 TRP A CB    1 
ATOM   562  C CG    . TRP A 1 102 ? 141.975 155.570 158.991 1.00 33.39  ? 102 TRP A CG    1 
ATOM   563  C CD1   . TRP A 1 102 ? 140.747 155.778 158.444 1.00 33.39  ? 102 TRP A CD1   1 
ATOM   564  C CD2   . TRP A 1 102 ? 142.928 156.002 158.013 1.00 33.39  ? 102 TRP A CD2   1 
ATOM   565  N NE1   . TRP A 1 102 ? 140.874 156.326 157.193 1.00 33.39  ? 102 TRP A NE1   1 
ATOM   566  C CE2   . TRP A 1 102 ? 142.204 156.471 156.903 1.00 33.39  ? 102 TRP A CE2   1 
ATOM   567  C CE3   . TRP A 1 102 ? 144.324 156.043 157.970 1.00 33.39  ? 102 TRP A CE3   1 
ATOM   568  C CZ2   . TRP A 1 102 ? 142.826 156.973 155.765 1.00 33.39  ? 102 TRP A CZ2   1 
ATOM   569  C CZ3   . TRP A 1 102 ? 144.940 156.543 156.840 1.00 33.39  ? 102 TRP A CZ3   1 
ATOM   570  C CH2   . TRP A 1 102 ? 144.192 157.001 155.753 1.00 33.39  ? 102 TRP A CH2   1 
ATOM   571  N N     . PHE A 1 103 ? 139.855 153.740 161.885 1.00 39.02  ? 103 PHE A N     1 
ATOM   572  C CA    . PHE A 1 103 ? 138.526 153.142 161.927 1.00 39.02  ? 103 PHE A CA    1 
ATOM   573  C C     . PHE A 1 103 ? 137.633 153.863 162.926 1.00 39.02  ? 103 PHE A C     1 
ATOM   574  O O     . PHE A 1 103 ? 136.441 154.061 162.670 1.00 39.02  ? 103 PHE A O     1 
ATOM   575  C CB    . PHE A 1 103 ? 138.638 151.658 162.270 1.00 39.02  ? 103 PHE A CB    1 
ATOM   576  C CG    . PHE A 1 103 ? 139.520 150.888 161.329 1.00 39.02  ? 103 PHE A CG    1 
ATOM   577  C CD1   . PHE A 1 103 ? 140.221 149.778 161.765 1.00 39.02  ? 103 PHE A CD1   1 
ATOM   578  C CD2   . PHE A 1 103 ? 139.638 151.265 160.005 1.00 39.02  ? 103 PHE A CD2   1 
ATOM   579  C CE1   . PHE A 1 103 ? 141.036 149.074 160.905 1.00 39.02  ? 103 PHE A CE1   1 
ATOM   580  C CE2   . PHE A 1 103 ? 140.446 150.559 159.145 1.00 39.02  ? 103 PHE A CE2   1 
ATOM   581  C CZ    . PHE A 1 103 ? 141.144 149.462 159.593 1.00 39.02  ? 103 PHE A CZ    1 
ATOM   582  N N     . ALA A 1 104 ? 138.192 154.263 164.071 1.00 43.27  ? 104 ALA A N     1 
ATOM   583  C CA    . ALA A 1 104 ? 137.420 155.042 165.034 1.00 43.27  ? 104 ALA A CA    1 
ATOM   584  C C     . ALA A 1 104 ? 136.966 156.367 164.435 1.00 43.27  ? 104 ALA A C     1 
ATOM   585  O O     . ALA A 1 104 ? 135.801 156.754 164.575 1.00 43.27  ? 104 ALA A O     1 
ATOM   586  C CB    . ALA A 1 104 ? 138.243 155.279 166.299 1.00 43.27  ? 104 ALA A CB    1 
ATOM   587  N N     . LYS A 1 105 ? 137.870 157.070 163.748 1.00 45.66  ? 105 LYS A N     1 
ATOM   588  C CA    . LYS A 1 105 ? 137.506 158.347 163.143 1.00 45.66  ? 105 LYS A CA    1 
ATOM   589  C C     . LYS A 1 105 ? 136.408 158.175 162.103 1.00 45.66  ? 105 LYS A C     1 
ATOM   590  O O     . LYS A 1 105 ? 135.462 158.969 162.052 1.00 45.66  ? 105 LYS A O     1 
ATOM   591  C CB    . LYS A 1 105 ? 138.729 159.007 162.510 1.00 45.66  ? 105 LYS A CB    1 
ATOM   592  C CG    . LYS A 1 105 ? 139.794 159.443 163.493 1.00 45.66  ? 105 LYS A CG    1 
ATOM   593  C CD    . LYS A 1 105 ? 141.144 159.517 162.808 1.00 45.66  ? 105 LYS A CD    1 
ATOM   594  C CE    . LYS A 1 105 ? 141.121 160.524 161.671 1.00 45.66  ? 105 LYS A CE    1 
ATOM   595  N NZ    . LYS A 1 105 ? 142.478 160.767 161.111 1.00 45.66  ? 105 LYS A NZ    1 
ATOM   596  N N     . LEU A 1 106 ? 136.512 157.143 161.263 1.00 41.52  ? 106 LEU A N     1 
ATOM   597  C CA    . LEU A 1 106 ? 135.520 156.980 160.206 1.00 41.52  ? 106 LEU A CA    1 
ATOM   598  C C     . LEU A 1 106 ? 134.231 156.327 160.689 1.00 41.52  ? 106 LEU A C     1 
ATOM   599  O O     . LEU A 1 106 ? 133.232 156.355 159.963 1.00 41.52  ? 106 LEU A O     1 
ATOM   600  C CB    . LEU A 1 106 ? 136.106 156.192 159.035 1.00 41.52  ? 106 LEU A CB    1 
ATOM   601  C CG    . LEU A 1 106 ? 136.825 157.061 157.997 1.00 41.52  ? 106 LEU A CG    1 
ATOM   602  C CD1   . LEU A 1 106 ? 135.831 158.031 157.379 1.00 41.52  ? 106 LEU A CD1   1 
ATOM   603  C CD2   . LEU A 1 106 ? 138.016 157.815 158.570 1.00 41.52  ? 106 LEU A CD2   1 
ATOM   604  N N     . ASN A 1 107 ? 134.225 155.739 161.884 1.00 58.91  ? 107 ASN A N     1 
ATOM   605  C CA    . ASN A 1 107 ? 132.978 155.345 162.526 1.00 58.91  ? 107 ASN A CA    1 
ATOM   606  C C     . ASN A 1 107 ? 132.456 156.416 163.472 1.00 58.91  ? 107 ASN A C     1 
ATOM   607  O O     . ASN A 1 107 ? 131.407 156.216 164.095 1.00 58.91  ? 107 ASN A O     1 
ATOM   608  C CB    . ASN A 1 107 ? 133.166 154.028 163.284 1.00 58.91  ? 107 ASN A CB    1 
ATOM   609  C CG    . ASN A 1 107 ? 131.883 153.228 163.388 1.00 58.91  ? 107 ASN A CG    1 
ATOM   610  O OD1   . ASN A 1 107 ? 130.848 153.624 162.853 1.00 58.91  ? 107 ASN A OD1   1 
ATOM   611  N ND2   . ASN A 1 107 ? 131.945 152.097 164.079 1.00 58.91  ? 107 ASN A ND2   1 
ATOM   612  N N     . ASN A 1 108 ? 133.181 157.527 163.600 1.00 64.14  ? 108 ASN A N     1 
ATOM   613  C CA    . ASN A 1 108 ? 132.905 158.716 164.397 1.00 64.14  ? 108 ASN A CA    1 
ATOM   614  C C     . ASN A 1 108 ? 133.199 158.487 165.874 1.00 64.14  ? 108 ASN A C     1 
ATOM   615  O O     . ASN A 1 108 ? 133.315 159.466 166.612 1.00 64.14  ? 108 ASN A O     1 
ATOM   616  C CB    . ASN A 1 108 ? 131.460 159.238 164.251 1.00 64.14  ? 108 ASN A CB    1 
ATOM   617  C CG    . ASN A 1 108 ? 130.998 159.295 162.806 1.00 64.14  ? 108 ASN A CG    1 
ATOM   618  O OD1   . ASN A 1 108 ? 131.316 160.235 162.078 1.00 64.14  ? 108 ASN A OD1   1 
ATOM   619  N ND2   . ASN A 1 108 ? 130.232 158.293 162.389 1.00 64.14  ? 108 ASN A ND2   1 
ATOM   620  N N     . LYS A 1 109 ? 133.474 157.250 166.294 1.00 82.86  ? 109 LYS A N     1 
ATOM   621  C CA    . LYS A 1 109 ? 133.606 156.915 167.707 1.00 82.86  ? 109 LYS A CA    1 
ATOM   622  C C     . LYS A 1 109 ? 134.610 157.820 168.405 1.00 82.86  ? 109 LYS A C     1 
ATOM   623  O O     . LYS A 1 109 ? 135.654 158.168 167.849 1.00 82.86  ? 109 LYS A O     1 
ATOM   624  C CB    . LYS A 1 109 ? 134.034 155.454 167.865 1.00 82.86  ? 109 LYS A CB    1 
ATOM   625  C CG    . LYS A 1 109 ? 133.049 154.448 167.305 1.00 82.86  ? 109 LYS A CG    1 
ATOM   626  C CD    . LYS A 1 109 ? 131.720 154.544 168.028 1.00 82.86  ? 109 LYS A CD    1 
ATOM   627  C CE    . LYS A 1 109 ? 131.862 154.104 169.476 1.00 82.86  ? 109 LYS A CE    1 
ATOM   628  N NZ    . LYS A 1 109 ? 132.224 152.665 169.587 1.00 82.86  ? 109 LYS A NZ    1 
ATOM   629  N N     . MET A 1 110 ? 134.267 158.207 169.634 1.00 93.14  ? 110 MET A N     1 
ATOM   630  C CA    . MET A 1 110 ? 135.090 159.091 170.454 1.00 93.14  ? 110 MET A CA    1 
ATOM   631  C C     . MET A 1 110 ? 135.280 160.441 169.758 1.00 93.14  ? 110 MET A C     1 
ATOM   632  O O     . MET A 1 110 ? 136.390 160.838 169.398 1.00 93.14  ? 110 MET A O     1 
ATOM   633  C CB    . MET A 1 110 ? 136.431 158.432 170.794 1.00 93.14  ? 110 MET A CB    1 
ATOM   634  C CG    . MET A 1 110 ? 137.304 159.195 171.782 1.00 93.14  ? 110 MET A CG    1 
ATOM   635  S SD    . MET A 1 110 ? 136.560 159.281 173.422 1.00 93.14  ? 110 MET A SD    1 
ATOM   636  C CE    . MET A 1 110 ? 137.361 160.737 174.087 1.00 93.14  ? 110 MET A CE    1 
ATOM   637  N N     . GLY A 1 111 ? 134.165 161.137 169.539 1.00 81.03  ? 111 GLY A N     1 
ATOM   638  C CA    . GLY A 1 111 ? 134.173 162.513 169.084 1.00 81.03  ? 111 GLY A CA    1 
ATOM   639  C C     . GLY A 1 111 ? 134.633 162.754 167.663 1.00 81.03  ? 111 GLY A C     1 
ATOM   640  O O     . GLY A 1 111 ? 134.525 163.890 167.188 1.00 81.03  ? 111 GLY A O     1 
ATOM   641  N N     . GLY A 1 112 ? 135.126 161.736 166.965 1.00 73.94  ? 112 GLY A N     1 
ATOM   642  C CA    . GLY A 1 112 ? 135.636 161.956 165.613 1.00 73.94  ? 112 GLY A CA    1 
ATOM   643  C C     . GLY A 1 112 ? 136.737 162.987 165.505 1.00 73.94  ? 112 GLY A C     1 
ATOM   644  O O     . GLY A 1 112 ? 136.753 163.776 164.551 1.00 73.94  ? 112 GLY A O     1 
ATOM   645  N N     . ASP A 1 113 ? 137.668 163.004 166.459 1.00 76.98  ? 113 ASP A N     1 
ATOM   646  C CA    . ASP A 1 113 ? 138.783 163.946 166.454 1.00 76.98  ? 113 ASP A CA    1 
ATOM   647  C C     . ASP A 1 113 ? 140.090 163.169 166.513 1.00 76.98  ? 113 ASP A C     1 
ATOM   648  O O     . ASP A 1 113 ? 140.339 162.443 167.482 1.00 76.98  ? 113 ASP A O     1 
ATOM   649  C CB    . ASP A 1 113 ? 138.678 164.928 167.622 1.00 76.98  ? 113 ASP A CB    1 
ATOM   650  C CG    . ASP A 1 113 ? 139.708 166.039 167.547 1.00 76.98  ? 113 ASP A CG    1 
ATOM   651  O OD1   . ASP A 1 113 ? 140.893 165.778 167.845 1.00 76.98  ? 113 ASP A OD1   1 
ATOM   652  O OD2   . ASP A 1 113 ? 139.333 167.175 167.188 1.00 76.98  ? 113 ASP A OD2   1 
ATOM   653  N N     . LEU A 1 114 ? 140.929 163.346 165.488 1.00 69.60  ? 114 LEU A N     1 
ATOM   654  C CA    . LEU A 1 114 ? 142.108 162.500 165.315 1.00 69.60  ? 114 LEU A CA    1 
ATOM   655  C C     . LEU A 1 114 ? 143.106 162.674 166.453 1.00 69.60  ? 114 LEU A C     1 
ATOM   656  O O     . LEU A 1 114 ? 143.595 161.688 167.017 1.00 69.60  ? 114 LEU A O     1 
ATOM   657  C CB    . LEU A 1 114 ? 142.775 162.806 163.973 1.00 69.60  ? 114 LEU A CB    1 
ATOM   658  C CG    . LEU A 1 114 ? 144.218 162.324 163.780 1.00 69.60  ? 114 LEU A CG    1 
ATOM   659  C CD1   . LEU A 1 114 ? 144.330 160.808 163.878 1.00 69.60  ? 114 LEU A CD1   1 
ATOM   660  C CD2   . LEU A 1 114 ? 144.782 162.823 162.457 1.00 69.60  ? 114 LEU A CD2   1 
ATOM   661  N N     . LYS A 1 115 ? 143.439 163.922 166.791 1.00 73.49  ? 115 LYS A N     1 
ATOM   662  C CA    . LYS A 1 115 ? 144.492 164.159 167.774 1.00 73.49  ? 115 LYS A CA    1 
ATOM   663  C C     . LYS A 1 115 ? 144.117 163.596 169.138 1.00 73.49  ? 115 LYS A C     1 
ATOM   664  O O     . LYS A 1 115 ? 144.925 162.916 169.787 1.00 73.49  ? 115 LYS A O     1 
ATOM   665  C CB    . LYS A 1 115 ? 144.786 165.656 167.874 1.00 73.49  ? 115 LYS A CB    1 
ATOM   666  C CG    . LYS A 1 115 ? 146.077 166.082 167.196 1.00 73.49  ? 115 LYS A CG    1 
ATOM   667  C CD    . LYS A 1 115 ? 147.286 165.474 167.887 1.00 73.49  ? 115 LYS A CD    1 
ATOM   668  C CE    . LYS A 1 115 ? 148.551 166.257 167.575 1.00 73.49  ? 115 LYS A CE    1 
ATOM   669  N NZ    . LYS A 1 115 ? 149.756 165.634 168.191 1.00 73.49  ? 115 LYS A NZ    1 
ATOM   670  N N     . LYS A 1 116 ? 142.889 163.841 169.587 1.00 80.92  ? 116 LYS A N     1 
ATOM   671  C CA    . LYS A 1 116 ? 142.530 163.362 170.911 1.00 80.92  ? 116 LYS A CA    1 
ATOM   672  C C     . LYS A 1 116 ? 142.150 161.885 170.915 1.00 80.92  ? 116 LYS A C     1 
ATOM   673  O O     . LYS A 1 116 ? 142.294 161.233 171.953 1.00 80.92  ? 116 LYS A O     1 
ATOM   674  C CB    . LYS A 1 116 ? 141.442 164.260 171.514 1.00 80.92  ? 116 LYS A CB    1 
ATOM   675  C CG    . LYS A 1 116 ? 140.093 164.302 170.830 1.00 80.92  ? 116 LYS A CG    1 
ATOM   676  C CD    . LYS A 1 116 ? 139.148 163.260 171.382 1.00 80.92  ? 116 LYS A CD    1 
ATOM   677  C CE    . LYS A 1 116 ? 137.780 163.408 170.757 1.00 80.92  ? 116 LYS A CE    1 
ATOM   678  N NZ    . LYS A 1 116 ? 136.846 162.388 171.274 1.00 80.92  ? 116 LYS A NZ    1 
ATOM   679  N N     . ILE A 1 117 ? 141.755 161.314 169.772 1.00 71.52  ? 117 ILE A N     1 
ATOM   680  C CA    . ILE A 1 117 ? 141.675 159.859 169.683 1.00 71.52  ? 117 ILE A CA    1 
ATOM   681  C C     . ILE A 1 117 ? 143.064 159.246 169.821 1.00 71.52  ? 117 ILE A C     1 
ATOM   682  O O     . ILE A 1 117 ? 143.238 158.203 170.463 1.00 71.52  ? 117 ILE A O     1 
ATOM   683  C CB    . ILE A 1 117 ? 140.989 159.434 168.370 1.00 71.52  ? 117 ILE A CB    1 
ATOM   684  C CG1   . ILE A 1 117 ? 139.470 159.567 168.495 1.00 71.52  ? 117 ILE A CG1   1 
ATOM   685  C CG2   . ILE A 1 117 ? 141.362 158.009 167.994 1.00 71.52  ? 117 ILE A CG2   1 
ATOM   686  C CD1   . ILE A 1 117 ? 138.725 159.217 167.227 1.00 71.52  ? 117 ILE A CD1   1 
ATOM   687  N N     . GLU A 1 118 ? 144.074 159.884 169.227 1.00 68.23  ? 118 GLU A N     1 
ATOM   688  C CA    . GLU A 1 118 ? 145.447 159.422 169.401 1.00 68.23  ? 118 GLU A CA    1 
ATOM   689  C C     . GLU A 1 118 ? 145.883 159.528 170.857 1.00 68.23  ? 118 GLU A C     1 
ATOM   690  O O     . GLU A 1 118 ? 146.583 158.646 171.370 1.00 68.23  ? 118 GLU A O     1 
ATOM   691  C CB    . GLU A 1 118 ? 146.388 160.220 168.499 1.00 68.23  ? 118 GLU A CB    1 
ATOM   692  C CG    . GLU A 1 118 ? 147.847 159.806 168.599 1.00 68.23  ? 118 GLU A CG    1 
ATOM   693  C CD    . GLU A 1 118 ? 148.687 160.814 169.358 1.00 68.23  ? 118 GLU A CD    1 
ATOM   694  O OE1   . GLU A 1 118 ? 148.178 161.917 169.647 1.00 68.23  ? 118 GLU A OE1   1 
ATOM   695  O OE2   . GLU A 1 118 ? 149.857 160.503 169.665 1.00 68.23  ? 118 GLU A OE2   1 
ATOM   696  N N     . THR A 1 119 ? 145.491 160.609 171.536 1.00 78.50  ? 119 THR A N     1 
ATOM   697  C CA    . THR A 1 119 ? 145.816 160.728 172.957 1.00 78.50  ? 119 THR A CA    1 
ATOM   698  C C     . THR A 1 119 ? 145.145 159.623 173.767 1.00 78.50  ? 119 THR A C     1 
ATOM   699  O O     . THR A 1 119 ? 145.751 159.065 174.689 1.00 78.50  ? 119 THR A O     1 
ATOM   700  C CB    . THR A 1 119 ? 145.407 162.097 173.501 1.00 78.50  ? 119 THR A CB    1 
ATOM   701  O OG1   . THR A 1 119 ? 143.992 162.264 173.373 1.00 78.50  ? 119 THR A OG1   1 
ATOM   702  C CG2   . THR A 1 119 ? 146.122 163.209 172.747 1.00 78.50  ? 119 THR A CG2   1 
ATOM   703  N N     . VAL A 1 120 ? 143.891 159.298 173.442 1.00 70.93  ? 120 VAL A N     1 
ATOM   704  C CA    . VAL A 1 120 ? 143.211 158.188 174.109 1.00 70.93  ? 120 VAL A CA    1 
ATOM   705  C C     . VAL A 1 120 ? 143.948 156.878 173.857 1.00 70.93  ? 120 VAL A C     1 
ATOM   706  O O     . VAL A 1 120 ? 144.136 156.068 174.773 1.00 70.93  ? 120 VAL A O     1 
ATOM   707  C CB    . VAL A 1 120 ? 141.741 158.108 173.657 1.00 70.93  ? 120 VAL A CB    1 
ATOM   708  C CG1   . VAL A 1 120 ? 141.065 156.893 174.261 1.00 70.93  ? 120 VAL A CG1   1 
ATOM   709  C CG2   . VAL A 1 120 ? 140.995 159.363 174.068 1.00 70.93  ? 120 VAL A CG2   1 
ATOM   710  N N     . GLY A 1 121 ? 144.364 156.642 172.613 1.00 65.53  ? 121 GLY A N     1 
ATOM   711  C CA    . GLY A 1 121 ? 145.110 155.430 172.312 1.00 65.53  ? 121 GLY A CA    1 
ATOM   712  C C     . GLY A 1 121 ? 146.408 155.343 173.090 1.00 65.53  ? 121 GLY A C     1 
ATOM   713  O O     . GLY A 1 121 ? 146.777 154.275 173.586 1.00 65.53  ? 121 GLY A O     1 
ATOM   714  N N     . ARG A 1 122 ? 147.114 156.468 173.214 1.00 73.35  ? 122 ARG A N     1 
ATOM   715  C CA    . ARG A 1 122 ? 148.330 156.502 174.022 1.00 73.35  ? 122 ARG A CA    1 
ATOM   716  C C     . ARG A 1 122 ? 148.024 156.221 175.490 1.00 73.35  ? 122 ARG A C     1 
ATOM   717  O O     . ARG A 1 122 ? 148.781 155.518 176.168 1.00 73.35  ? 122 ARG A O     1 
ATOM   718  C CB    . ARG A 1 122 ? 149.024 157.854 173.863 1.00 73.35  ? 122 ARG A CB    1 
ATOM   719  C CG    . ARG A 1 122 ? 150.209 158.066 174.791 1.00 73.35  ? 122 ARG A CG    1 
ATOM   720  C CD    . ARG A 1 122 ? 151.316 157.052 174.525 1.00 73.35  ? 122 ARG A CD    1 
ATOM   721  N NE    . ARG A 1 122 ? 151.590 156.862 173.104 1.00 73.35  ? 122 ARG A NE    1 
ATOM   722  C CZ    . ARG A 1 122 ? 152.082 157.791 172.293 1.00 73.35  ? 122 ARG A CZ    1 
ATOM   723  N NH1   . ARG A 1 122 ? 152.399 158.998 172.732 1.00 73.35  ? 122 ARG A NH1   1 
ATOM   724  N NH2   . ARG A 1 122 ? 152.269 157.497 171.010 1.00 73.35  ? 122 ARG A NH2   1 
ATOM   725  N N     . TYR A 1 123 ? 146.917 156.769 175.996 1.00 77.28  ? 123 TYR A N     1 
ATOM   726  C CA    . TYR A 1 123 ? 146.523 156.523 177.380 1.00 77.28  ? 123 TYR A CA    1 
ATOM   727  C C     . TYR A 1 123 ? 146.261 155.041 177.628 1.00 77.28  ? 123 TYR A C     1 
ATOM   728  O O     . TYR A 1 123 ? 146.706 154.482 178.637 1.00 77.28  ? 123 TYR A O     1 
ATOM   729  C CB    . TYR A 1 123 ? 145.286 157.359 177.710 1.00 77.28  ? 123 TYR A CB    1 
ATOM   730  C CG    . TYR A 1 123 ? 144.565 156.961 178.976 1.00 77.28  ? 123 TYR A CG    1 
ATOM   731  C CD1   . TYR A 1 123 ? 145.228 156.918 180.194 1.00 77.28  ? 123 TYR A CD1   1 
ATOM   732  C CD2   . TYR A 1 123 ? 143.216 156.636 178.952 1.00 77.28  ? 123 TYR A CD2   1 
ATOM   733  C CE1   . TYR A 1 123 ? 144.568 156.559 181.351 1.00 77.28  ? 123 TYR A CE1   1 
ATOM   734  C CE2   . TYR A 1 123 ? 142.547 156.276 180.103 1.00 77.28  ? 123 TYR A CE2   1 
ATOM   735  C CZ    . TYR A 1 123 ? 143.227 156.238 181.300 1.00 77.28  ? 123 TYR A CZ    1 
ATOM   736  O OH    . TYR A 1 123 ? 142.564 155.877 182.450 1.00 77.28  ? 123 TYR A OH    1 
ATOM   737  N N     . LEU A 1 124 ? 145.550 154.385 176.711 1.00 63.96  ? 124 LEU A N     1 
ATOM   738  C CA    . LEU A 1 124 ? 145.293 152.952 176.856 1.00 63.96  ? 124 LEU A CA    1 
ATOM   739  C C     . LEU A 1 124 ? 146.559 152.118 176.679 1.00 63.96  ? 124 LEU A C     1 
ATOM   740  O O     . LEU A 1 124 ? 146.716 151.080 177.340 1.00 63.96  ? 124 LEU A O     1 
ATOM   741  C CB    . LEU A 1 124 ? 144.198 152.523 175.880 1.00 63.96  ? 124 LEU A CB    1 
ATOM   742  C CG    . LEU A 1 124 ? 142.754 152.791 176.324 1.00 63.96  ? 124 LEU A CG    1 
ATOM   743  C CD1   . LEU A 1 124 ? 142.382 154.251 176.368 1.00 63.96  ? 124 LEU A CD1   1 
ATOM   744  C CD2   . LEU A 1 124 ? 141.832 152.101 175.358 1.00 63.96  ? 124 LEU A CD2   1 
ATOM   745  N N     . ILE A 1 125 ? 147.473 152.548 175.807 1.00 62.62  ? 125 ILE A N     1 
ATOM   746  C CA    . ILE A 1 125 ? 148.772 151.886 175.717 1.00 62.62  ? 125 ILE A CA    1 
ATOM   747  C C     . ILE A 1 125 ? 149.505 151.987 177.048 1.00 62.62  ? 125 ILE A C     1 
ATOM   748  O O     . ILE A 1 125 ? 150.134 151.026 177.505 1.00 62.62  ? 125 ILE A O     1 
ATOM   749  C CB    . ILE A 1 125 ? 149.597 152.478 174.559 1.00 62.62  ? 125 ILE A CB    1 
ATOM   750  C CG1   . ILE A 1 125 ? 149.160 151.865 173.228 1.00 62.62  ? 125 ILE A CG1   1 
ATOM   751  C CG2   . ILE A 1 125 ? 151.085 152.261 174.782 1.00 62.62  ? 125 ILE A CG2   1 
ATOM   752  C CD1   . ILE A 1 125 ? 149.789 152.517 172.020 1.00 62.62  ? 125 ILE A CD1   1 
ATOM   753  N N     . GLU A 1 126 ? 149.424 153.150 177.697 1.00 68.58  ? 126 GLU A N     1 
ATOM   754  C CA    . GLU A 1 126 ? 150.022 153.307 179.019 1.00 68.58  ? 126 GLU A CA    1 
ATOM   755  C C     . GLU A 1 126 ? 149.333 152.416 180.046 1.00 68.58  ? 126 GLU A C     1 
ATOM   756  O O     . GLU A 1 126 ? 149.979 151.902 180.965 1.00 68.58  ? 126 GLU A O     1 
ATOM   757  C CB    . GLU A 1 126 ? 149.960 154.771 179.453 1.00 68.58  ? 126 GLU A CB    1 
ATOM   758  C CG    . GLU A 1 126 ? 150.992 155.663 178.781 1.00 68.58  ? 126 GLU A CG    1 
ATOM   759  C CD    . GLU A 1 126 ? 152.322 154.967 178.570 1.00 68.58  ? 126 GLU A CD    1 
ATOM   760  O OE1   . GLU A 1 126 ? 152.968 154.594 179.572 1.00 68.58  ? 126 GLU A OE1   1 
ATOM   761  O OE2   . GLU A 1 126 ? 152.723 154.795 177.400 1.00 68.58  ? 126 GLU A OE2   1 
ATOM   762  N N     . ILE A 1 127 ? 148.017 152.237 179.916 1.00 64.10  ? 127 ILE A N     1 
ATOM   763  C CA    . ILE A 1 127 ? 147.294 151.339 180.817 1.00 64.10  ? 127 ILE A CA    1 
ATOM   764  C C     . ILE A 1 127 ? 147.825 149.917 180.688 1.00 64.10  ? 127 ILE A C     1 
ATOM   765  O O     . ILE A 1 127 ? 148.065 149.230 181.689 1.00 64.10  ? 127 ILE A O     1 
ATOM   766  C CB    . ILE A 1 127 ? 145.781 151.397 180.543 1.00 64.10  ? 127 ILE A CB    1 
ATOM   767  C CG1   . ILE A 1 127 ? 145.233 152.795 180.828 1.00 64.10  ? 127 ILE A CG1   1 
ATOM   768  C CG2   . ILE A 1 127 ? 145.046 150.349 181.365 1.00 64.10  ? 127 ILE A CG2   1 
ATOM   769  C CD1   . ILE A 1 127 ? 143.819 152.996 180.340 1.00 64.10  ? 127 ILE A CD1   1 
ATOM   770  N N     . TRP A 1 128 ? 147.996 149.448 179.450 1.00 57.08  ? 128 TRP A N     1 
ATOM   771  C CA    . TRP A 1 128 ? 148.562 148.114 179.244 1.00 57.08  ? 128 TRP A CA    1 
ATOM   772  C C     . TRP A 1 128 ? 150.000 148.029 179.745 1.00 57.08  ? 128 TRP A C     1 
ATOM   773  O O     . TRP A 1 128 ? 150.407 147.008 180.314 1.00 57.08  ? 128 TRP A O     1 
ATOM   774  C CB    . TRP A 1 128 ? 148.466 147.708 177.774 1.00 57.08  ? 128 TRP A CB    1 
ATOM   775  C CG    . TRP A 1 128 ? 147.061 147.465 177.325 1.00 57.08  ? 128 TRP A CG    1 
ATOM   776  C CD1   . TRP A 1 128 ? 145.947 147.432 178.110 1.00 57.08  ? 128 TRP A CD1   1 
ATOM   777  C CD2   . TRP A 1 128 ? 146.619 147.200 175.990 1.00 57.08  ? 128 TRP A CD2   1 
ATOM   778  N NE1   . TRP A 1 128 ? 144.837 147.169 177.346 1.00 57.08  ? 128 TRP A NE1   1 
ATOM   779  C CE2   . TRP A 1 128 ? 145.223 147.023 176.041 1.00 57.08  ? 128 TRP A CE2   1 
ATOM   780  C CE3   . TRP A 1 128 ? 147.267 147.099 174.757 1.00 57.08  ? 128 TRP A CE3   1 
ATOM   781  C CZ2   . TRP A 1 128 ? 144.465 146.751 174.907 1.00 57.08  ? 128 TRP A CZ2   1 
ATOM   782  C CZ3   . TRP A 1 128 ? 146.512 146.829 173.633 1.00 57.08  ? 128 TRP A CZ3   1 
ATOM   783  C CH2   . TRP A 1 128 ? 145.125 146.659 173.715 1.00 57.08  ? 128 TRP A CH2   1 
ATOM   784  N N     . LYS A 1 129 ? 150.782 149.093 179.550 1.00 67.11  ? 129 LYS A N     1 
ATOM   785  C CA    . LYS A 1 129 ? 152.139 149.125 180.086 1.00 67.11  ? 129 LYS A CA    1 
ATOM   786  C C     . LYS A 1 129 ? 152.134 148.966 181.600 1.00 67.11  ? 129 LYS A C     1 
ATOM   787  O O     . LYS A 1 129 ? 152.939 148.211 182.159 1.00 67.11  ? 129 LYS A O     1 
ATOM   788  C CB    . LYS A 1 129 ? 152.819 150.438 179.699 1.00 67.11  ? 129 LYS A CB    1 
ATOM   789  C CG    . LYS A 1 129 ? 153.274 150.529 178.254 1.00 67.11  ? 129 LYS A CG    1 
ATOM   790  C CD    . LYS A 1 129 ? 154.786 150.453 178.151 1.00 67.11  ? 129 LYS A CD    1 
ATOM   791  C CE    . LYS A 1 129 ? 155.288 151.264 176.967 1.00 67.11  ? 129 LYS A CE    1 
ATOM   792  N NZ    . LYS A 1 129 ? 156.773 151.351 176.937 1.00 67.11  ? 129 LYS A NZ    1 
ATOM   793  N N     . ALA A 1 130 ? 151.232 149.675 182.279 1.00 72.14  ? 130 ALA A N     1 
ATOM   794  C CA    . ALA A 1 130 ? 151.165 149.607 183.734 1.00 72.14  ? 130 ALA A CA    1 
ATOM   795  C C     . ALA A 1 130 ? 150.703 148.237 184.209 1.00 72.14  ? 130 ALA A C     1 
ATOM   796  O O     . ALA A 1 130 ? 151.286 147.666 185.139 1.00 72.14  ? 130 ALA A O     1 
ATOM   797  C CB    . ALA A 1 130 ? 150.236 150.697 184.264 1.00 72.14  ? 130 ALA A CB    1 
ATOM   798  N N     . VAL A 1 131 ? 149.655 147.691 183.586 1.00 69.44  ? 131 VAL A N     1 
ATOM   799  C CA    . VAL A 1 131 ? 149.141 146.399 184.026 1.00 69.44  ? 131 VAL A CA    1 
ATOM   800  C C     . VAL A 1 131 ? 150.130 145.286 183.705 1.00 69.44  ? 131 VAL A C     1 
ATOM   801  O O     . VAL A 1 131 ? 150.103 144.230 184.346 1.00 69.44  ? 131 VAL A O     1 
ATOM   802  C CB    . VAL A 1 131 ? 147.756 146.119 183.407 1.00 69.44  ? 131 VAL A CB    1 
ATOM   803  C CG1   . VAL A 1 131 ? 147.850 145.971 181.905 1.00 69.44  ? 131 VAL A CG1   1 
ATOM   804  C CG2   . VAL A 1 131 ? 147.100 144.905 184.046 1.00 69.44  ? 131 VAL A CG2   1 
ATOM   805  N N     . GLY A 1 132 ? 151.033 145.507 182.751 1.00 66.43  ? 132 GLY A N     1 
ATOM   806  C CA    . GLY A 1 132 ? 152.054 144.525 182.446 1.00 66.43  ? 132 GLY A CA    1 
ATOM   807  C C     . GLY A 1 132 ? 152.218 144.255 180.967 1.00 66.43  ? 132 GLY A C     1 
ATOM   808  O O     . GLY A 1 132 ? 151.289 143.800 180.293 1.00 66.43  ? 132 GLY A O     1 
ATOM   809  N N     . MET A 1 133 ? 153.417 144.529 180.459 1.00 73.67  ? 133 MET A N     1 
ATOM   810  C CA    . MET A 1 133 ? 153.719 144.413 179.042 1.00 73.67  ? 133 MET A CA    1 
ATOM   811  C C     . MET A 1 133 ? 155.230 144.475 178.876 1.00 73.67  ? 133 MET A C     1 
ATOM   812  O O     . MET A 1 133 ? 155.875 145.383 179.405 1.00 73.67  ? 133 MET A O     1 
ATOM   813  C CB    . MET A 1 133 ? 153.048 145.535 178.243 1.00 73.67  ? 133 MET A CB    1 
ATOM   814  C CG    . MET A 1 133 ? 153.209 145.418 176.746 1.00 73.67  ? 133 MET A CG    1 
ATOM   815  S SD    . MET A 1 133 ? 152.401 143.931 176.139 1.00 73.67  ? 133 MET A SD    1 
ATOM   816  C CE    . MET A 1 133 ? 150.677 144.388 176.298 1.00 73.67  ? 133 MET A CE    1 
ATOM   817  N N     . ASP A 1 134 ? 155.792 143.515 178.143 1.00 85.00  ? 134 ASP A N     1 
ATOM   818  C CA    . ASP A 1 134 ? 157.244 143.448 177.971 1.00 85.00  ? 134 ASP A CA    1 
ATOM   819  C C     . ASP A 1 134 ? 157.635 144.256 176.739 1.00 85.00  ? 134 ASP A C     1 
ATOM   820  O O     . ASP A 1 134 ? 157.726 143.740 175.624 1.00 85.00  ? 134 ASP A O     1 
ATOM   821  C CB    . ASP A 1 134 ? 157.723 142.004 177.883 1.00 85.00  ? 134 ASP A CB    1 
ATOM   822  C CG    . ASP A 1 134 ? 157.007 141.207 176.813 1.00 85.00  ? 134 ASP A CG    1 
ATOM   823  O OD1   . ASP A 1 134 ? 155.977 141.681 176.289 1.00 85.00  ? 134 ASP A OD1   1 
ATOM   824  O OD2   . ASP A 1 134 ? 157.502 140.112 176.479 1.00 85.00  ? 134 ASP A OD2   1 
ATOM   825  N N     . VAL A 1 135 ? 157.874 145.546 176.947 1.00 89.70  ? 135 VAL A N     1 
ATOM   826  C CA    . VAL A 1 135 ? 158.376 146.412 175.890 1.00 89.70  ? 135 VAL A CA    1 
ATOM   827  C C     . VAL A 1 135 ? 159.897 146.439 175.832 1.00 89.70  ? 135 VAL A C     1 
ATOM   828  O O     . VAL A 1 135 ? 160.452 146.936 174.839 1.00 89.70  ? 135 VAL A O     1 
ATOM   829  C CB    . VAL A 1 135 ? 157.822 147.843 176.034 1.00 89.70  ? 135 VAL A CB    1 
ATOM   830  C CG1   . VAL A 1 135 ? 156.316 147.804 176.220 1.00 89.70  ? 135 VAL A CG1   1 
ATOM   831  C CG2   . VAL A 1 135 ? 158.492 148.551 177.201 1.00 89.70  ? 135 VAL A CG2   1 
ATOM   832  N N     . GLU A 1 136 ? 160.588 145.931 176.855 1.00 95.92  ? 136 GLU A N     1 
ATOM   833  C CA    . GLU A 1 136 ? 162.047 145.921 176.837 1.00 95.92  ? 136 GLU A CA    1 
ATOM   834  C C     . GLU A 1 136 ? 162.582 145.017 175.734 1.00 95.92  ? 136 GLU A C     1 
ATOM   835  O O     . GLU A 1 136 ? 163.557 145.365 175.057 1.00 95.92  ? 136 GLU A O     1 
ATOM   836  C CB    . GLU A 1 136 ? 162.584 145.480 178.200 1.00 95.92  ? 136 GLU A CB    1 
ATOM   837  C CG    . GLU A 1 136 ? 162.244 146.426 179.341 1.00 95.92  ? 136 GLU A CG    1 
ATOM   838  C CD    . GLU A 1 136 ? 160.890 146.132 179.960 1.00 95.92  ? 136 GLU A CD    1 
ATOM   839  O OE1   . GLU A 1 136 ? 160.253 145.137 179.555 1.00 95.92  ? 136 GLU A OE1   1 
ATOM   840  O OE2   . GLU A 1 136 ? 160.463 146.897 180.850 1.00 95.92  ? 136 GLU A OE2   1 
ATOM   841  N N     . GLY A 1 137 ? 161.960 143.857 175.537 1.00 84.21  ? 137 GLY A N     1 
ATOM   842  C CA    . GLY A 1 137 ? 162.408 142.909 174.539 1.00 84.21  ? 137 GLY A CA    1 
ATOM   843  C C     . GLY A 1 137 ? 161.986 143.199 173.119 1.00 84.21  ? 137 GLY A C     1 
ATOM   844  O O     . GLY A 1 137 ? 162.443 142.517 172.197 1.00 84.21  ? 137 GLY A O     1 
ATOM   845  N N     . GLY A 1 138 ? 161.126 144.193 172.908 1.00 73.63  ? 138 GLY A N     1 
ATOM   846  C CA    . GLY A 1 138 ? 160.697 144.528 171.566 1.00 73.63  ? 138 GLY A CA    1 
ATOM   847  C C     . GLY A 1 138 ? 159.788 143.512 170.918 1.00 73.63  ? 138 GLY A C     1 
ATOM   848  O O     . GLY A 1 138 ? 159.585 143.563 169.702 1.00 73.63  ? 138 GLY A O     1 
ATOM   849  N N     . LYS A 1 139 ? 159.232 142.581 171.696 1.00 58.47  ? 139 LYS A N     1 
ATOM   850  C CA    . LYS A 1 139 ? 158.326 141.591 171.126 1.00 58.47  ? 139 LYS A CA    1 
ATOM   851  C C     . LYS A 1 139 ? 156.980 142.204 170.767 1.00 58.47  ? 139 LYS A C     1 
ATOM   852  O O     . LYS A 1 139 ? 156.317 141.738 169.834 1.00 58.47  ? 139 LYS A O     1 
ATOM   853  C CB    . LYS A 1 139 ? 158.135 140.430 172.101 1.00 58.47  ? 139 LYS A CB    1 
ATOM   854  C CG    . LYS A 1 139 ? 159.409 139.664 172.416 1.00 58.47  ? 139 LYS A CG    1 
ATOM   855  C CD    . LYS A 1 139 ? 159.786 138.727 171.280 1.00 58.47  ? 139 LYS A CD    1 
ATOM   856  C CE    . LYS A 1 139 ? 161.290 138.517 171.216 1.00 58.47  ? 139 LYS A CE    1 
ATOM   857  N NZ    . LYS A 1 139 ? 161.763 138.324 169.817 1.00 58.47  ? 139 LYS A NZ    1 
ATOM   858  N N     . VAL A 1 140 ? 156.560 143.238 171.488 1.00 58.86  ? 140 VAL A N     1 
ATOM   859  C CA    . VAL A 1 140 ? 155.279 143.891 171.254 1.00 58.86  ? 140 VAL A CA    1 
ATOM   860  C C     . VAL A 1 140 ? 155.498 145.107 170.368 1.00 58.86  ? 140 VAL A C     1 
ATOM   861  O O     . VAL A 1 140 ? 156.545 145.763 170.417 1.00 58.86  ? 140 VAL A O     1 
ATOM   862  C CB    . VAL A 1 140 ? 154.597 144.275 172.584 1.00 58.86  ? 140 VAL A CB    1 
ATOM   863  C CG1   . VAL A 1 140 ? 154.470 143.052 173.470 1.00 58.86  ? 140 VAL A CG1   1 
ATOM   864  C CG2   . VAL A 1 140 ? 155.380 145.368 173.295 1.00 58.86  ? 140 VAL A CG2   1 
ATOM   865  N N     . GLU A 1 141 ? 154.505 145.403 169.533 1.00 47.46  ? 141 GLU A N     1 
ATOM   866  C CA    . GLU A 1 141 ? 154.580 146.510 168.588 1.00 47.46  ? 141 GLU A CA    1 
ATOM   867  C C     . GLU A 1 141 ? 153.296 147.319 168.667 1.00 47.46  ? 141 GLU A C     1 
ATOM   868  O O     . GLU A 1 141 ? 152.222 146.817 168.325 1.00 47.46  ? 141 GLU A O     1 
ATOM   869  C CB    . GLU A 1 141 ? 154.812 146.001 167.163 1.00 47.46  ? 141 GLU A CB    1 
ATOM   870  C CG    . GLU A 1 141 ? 156.205 145.441 166.933 1.00 47.46  ? 141 GLU A CG    1 
ATOM   871  C CD    . GLU A 1 141 ? 156.400 144.923 165.524 1.00 47.46  ? 141 GLU A CD    1 
ATOM   872  O OE1   . GLU A 1 141 ? 156.440 145.747 164.587 1.00 47.46  ? 141 GLU A OE1   1 
ATOM   873  O OE2   . GLU A 1 141 ? 156.515 143.691 165.353 1.00 47.46  ? 141 GLU A OE2   1 
ATOM   874  N N     . PHE A 1 142 ? 153.411 148.569 169.109 1.00 47.38  ? 142 PHE A N     1 
ATOM   875  C CA    . PHE A 1 142 ? 152.272 149.480 169.196 1.00 47.38  ? 142 PHE A CA    1 
ATOM   876  C C     . PHE A 1 142 ? 152.176 150.230 167.875 1.00 47.38  ? 142 PHE A C     1 
ATOM   877  O O     . PHE A 1 142 ? 152.833 151.254 167.679 1.00 47.38  ? 142 PHE A O     1 
ATOM   878  C CB    . PHE A 1 142 ? 152.440 150.435 170.372 1.00 47.38  ? 142 PHE A CB    1 
ATOM   879  C CG    . PHE A 1 142 ? 152.216 149.793 171.710 1.00 47.38  ? 142 PHE A CG    1 
ATOM   880  C CD1   . PHE A 1 142 ? 151.070 149.058 171.956 1.00 47.38  ? 142 PHE A CD1   1 
ATOM   881  C CD2   . PHE A 1 142 ? 153.160 149.909 172.715 1.00 47.38  ? 142 PHE A CD2   1 
ATOM   882  C CE1   . PHE A 1 142 ? 150.863 148.462 173.184 1.00 47.38  ? 142 PHE A CE1   1 
ATOM   883  C CE2   . PHE A 1 142 ? 152.960 149.313 173.945 1.00 47.38  ? 142 PHE A CE2   1 
ATOM   884  C CZ    . PHE A 1 142 ? 151.810 148.589 174.179 1.00 47.38  ? 142 PHE A CZ    1 
ATOM   885  N N     . LEU A 1 143 ? 151.353 149.722 166.963 1.00 38.36  ? 143 LEU A N     1 
ATOM   886  C CA    . LEU A 1 143 ? 151.230 150.275 165.621 1.00 38.36  ? 143 LEU A CA    1 
ATOM   887  C C     . LEU A 1 143 ? 149.887 150.972 165.462 1.00 38.36  ? 143 LEU A C     1 
ATOM   888  O O     . LEU A 1 143 ? 148.836 150.369 165.699 1.00 38.36  ? 143 LEU A O     1 
ATOM   889  C CB    . LEU A 1 143 ? 151.382 149.182 164.564 1.00 38.36  ? 143 LEU A CB    1 
ATOM   890  C CG    . LEU A 1 143 ? 152.773 148.559 164.471 1.00 38.36  ? 143 LEU A CG    1 
ATOM   891  C CD1   . LEU A 1 143 ? 152.867 147.660 163.258 1.00 38.36  ? 143 LEU A CD1   1 
ATOM   892  C CD2   . LEU A 1 143 ? 153.839 149.640 164.424 1.00 38.36  ? 143 LEU A CD2   1 
ATOM   893  N N     . TRP A 1 144 ? 149.930 152.237 165.056 1.00 41.49  ? 144 TRP A N     1 
ATOM   894  C CA    . TRP A 1 144 ? 148.730 153.001 164.758 1.00 41.49  ? 144 TRP A CA    1 
ATOM   895  C C     . TRP A 1 144 ? 148.356 152.804 163.296 1.00 41.49  ? 144 TRP A C     1 
ATOM   896  O O     . TRP A 1 144 ? 149.218 152.850 162.414 1.00 41.49  ? 144 TRP A O     1 
ATOM   897  C CB    . TRP A 1 144 ? 148.946 154.487 165.049 1.00 41.49  ? 144 TRP A CB    1 
ATOM   898  C CG    . TRP A 1 144 ? 149.572 154.762 166.383 1.00 41.49  ? 144 TRP A CG    1 
ATOM   899  C CD1   . TRP A 1 144 ? 150.866 154.524 166.749 1.00 41.49  ? 144 TRP A CD1   1 
ATOM   900  C CD2   . TRP A 1 144 ? 148.932 155.336 167.527 1.00 41.49  ? 144 TRP A CD2   1 
ATOM   901  N NE1   . TRP A 1 144 ? 151.068 154.909 168.051 1.00 41.49  ? 144 TRP A NE1   1 
ATOM   902  C CE2   . TRP A 1 144 ? 149.897 155.412 168.551 1.00 41.49  ? 144 TRP A CE2   1 
ATOM   903  C CE3   . TRP A 1 144 ? 147.638 155.794 167.786 1.00 41.49  ? 144 TRP A CE3   1 
ATOM   904  C CZ2   . TRP A 1 144 ? 149.607 155.925 169.812 1.00 41.49  ? 144 TRP A CZ2   1 
ATOM   905  C CZ3   . TRP A 1 144 ? 147.352 156.301 169.039 1.00 41.49  ? 144 TRP A CZ3   1 
ATOM   906  C CH2   . TRP A 1 144 ? 148.331 156.363 170.036 1.00 41.49  ? 144 TRP A CH2   1 
ATOM   907  N N     . SER A 1 145 ? 147.066 152.575 163.045 1.00 32.72  ? 145 SER A N     1 
ATOM   908  C CA    . SER A 1 145 ? 146.621 152.314 161.679 1.00 32.72  ? 145 SER A CA    1 
ATOM   909  C C     . SER A 1 145 ? 146.899 153.500 160.765 1.00 32.72  ? 145 SER A C     1 
ATOM   910  O O     . SER A 1 145 ? 147.364 153.322 159.634 1.00 32.72  ? 145 SER A O     1 
ATOM   911  C CB    . SER A 1 145 ? 145.135 151.965 161.662 1.00 32.72  ? 145 SER A CB    1 
ATOM   912  O OG    . SER A 1 145 ? 144.897 150.732 162.314 1.00 32.72  ? 145 SER A OG    1 
ATOM   913  N N     . SER A 1 146 ? 146.630 154.718 161.237 1.00 34.72  ? 146 SER A N     1 
ATOM   914  C CA    . SER A 1 146 ? 146.820 155.893 160.391 1.00 34.72  ? 146 SER A CA    1 
ATOM   915  C C     . SER A 1 146 ? 148.276 156.042 159.971 1.00 34.72  ? 146 SER A C     1 
ATOM   916  O O     . SER A 1 146 ? 148.572 156.296 158.799 1.00 34.72  ? 146 SER A O     1 
ATOM   917  C CB    . SER A 1 146 ? 146.338 157.148 161.116 1.00 34.72  ? 146 SER A CB    1 
ATOM   918  O OG    . SER A 1 146 ? 146.873 157.215 162.426 1.00 34.72  ? 146 SER A OG    1 
ATOM   919  N N     . LYS A 1 147 ? 149.202 155.876 160.917 1.00 30.27  ? 147 LYS A N     1 
ATOM   920  C CA    . LYS A 1 147 ? 150.617 156.032 160.600 1.00 30.27  ? 147 LYS A CA    1 
ATOM   921  C C     . LYS A 1 147 ? 151.073 154.979 159.599 1.00 30.27  ? 147 LYS A C     1 
ATOM   922  O O     . LYS A 1 147 ? 151.757 155.293 158.618 1.00 30.27  ? 147 LYS A O     1 
ATOM   923  C CB    . LYS A 1 147 ? 151.450 155.961 161.881 1.00 30.27  ? 147 LYS A CB    1 
ATOM   924  C CG    . LYS A 1 147 ? 152.827 156.601 161.775 1.00 30.27  ? 147 LYS A CG    1 
ATOM   925  C CD    . LYS A 1 147 ? 153.878 155.605 161.307 1.00 30.27  ? 147 LYS A CD    1 
ATOM   926  C CE    . LYS A 1 147 ? 155.280 156.081 161.644 1.00 30.27  ? 147 LYS A CE    1 
ATOM   927  N NZ    . LYS A 1 147 ? 156.321 155.184 161.070 1.00 30.27  ? 147 LYS A NZ    1 
ATOM   928  N N     . GLU A 1 148 ? 150.693 153.720 159.825 1.00 29.99  ? 148 GLU A N     1 
ATOM   929  C CA    . GLU A 1 148 ? 151.122 152.652 158.929 1.00 29.99  ? 148 GLU A CA    1 
ATOM   930  C C     . GLU A 1 148 ? 150.536 152.825 157.533 1.00 29.99  ? 148 GLU A C     1 
ATOM   931  O O     . GLU A 1 148 ? 151.225 152.592 156.532 1.00 29.99  ? 148 GLU A O     1 
ATOM   932  C CB    . GLU A 1 148 ? 150.738 151.293 159.510 1.00 29.99  ? 148 GLU A CB    1 
ATOM   933  C CG    . GLU A 1 148 ? 151.666 150.815 160.609 1.00 29.99  ? 148 GLU A CG    1 
ATOM   934  C CD    . GLU A 1 148 ? 153.031 150.425 160.083 1.00 29.99  ? 148 GLU A CD    1 
ATOM   935  O OE1   . GLU A 1 148 ? 153.103 149.519 159.227 1.00 29.99  ? 148 GLU A OE1   1 
ATOM   936  O OE2   . GLU A 1 148 ? 154.034 151.026 160.522 1.00 29.99  ? 148 GLU A OE2   1 
ATOM   937  N N     . ILE A 1 149 ? 149.271 153.235 157.442 1.00 25.17  ? 149 ILE A N     1 
ATOM   938  C CA    . ILE A 1 149 ? 148.658 153.423 156.132 1.00 25.17  ? 149 ILE A CA    1 
ATOM   939  C C     . ILE A 1 149 ? 149.285 154.610 155.409 1.00 25.17  ? 149 ILE A C     1 
ATOM   940  O O     . ILE A 1 149 ? 149.567 154.540 154.209 1.00 25.17  ? 149 ILE A O     1 
ATOM   941  C CB    . ILE A 1 149 ? 147.134 153.574 156.273 1.00 25.17  ? 149 ILE A CB    1 
ATOM   942  C CG1   . ILE A 1 149 ? 146.537 152.301 156.873 1.00 25.17  ? 149 ILE A CG1   1 
ATOM   943  C CG2   . ILE A 1 149 ? 146.506 153.867 154.925 1.00 25.17  ? 149 ILE A CG2   1 
ATOM   944  C CD1   . ILE A 1 149 ? 145.148 152.483 157.440 1.00 25.17  ? 149 ILE A CD1   1 
ATOM   945  N N     . ASN A 1 150 ? 149.532 155.713 156.120 1.00 27.12  ? 150 ASN A N     1 
ATOM   946  C CA    . ASN A 1 150 ? 150.210 156.838 155.487 1.00 27.12  ? 150 ASN A CA    1 
ATOM   947  C C     . ASN A 1 150 ? 151.623 156.467 155.057 1.00 27.12  ? 150 ASN A C     1 
ATOM   948  O O     . ASN A 1 150 ? 152.143 157.024 154.084 1.00 27.12  ? 150 ASN A O     1 
ATOM   949  C CB    . ASN A 1 150 ? 150.237 158.038 156.433 1.00 27.12  ? 150 ASN A CB    1 
ATOM   950  C CG    . ASN A 1 150 ? 148.870 158.659 156.620 1.00 27.12  ? 150 ASN A CG    1 
ATOM   951  O OD1   . ASN A 1 150 ? 147.884 158.201 156.044 1.00 27.12  ? 150 ASN A OD1   1 
ATOM   952  N ND2   . ASN A 1 150 ? 148.804 159.711 157.428 1.00 27.12  ? 150 ASN A ND2   1 
ATOM   953  N N     . ALA A 1 151 ? 152.261 155.535 155.768 1.00 29.50  ? 151 ALA A N     1 
ATOM   954  C CA    . ALA A 1 151 ? 153.607 155.120 155.391 1.00 29.50  ? 151 ALA A CA    1 
ATOM   955  C C     . ALA A 1 151 ? 153.598 154.220 154.160 1.00 29.50  ? 151 ALA A C     1 
ATOM   956  O O     . ALA A 1 151 ? 154.445 154.370 153.273 1.00 29.50  ? 151 ALA A O     1 
ATOM   957  C CB    . ALA A 1 151 ? 154.284 154.415 156.564 1.00 29.50  ? 151 ALA A CB    1 
ATOM   958  N N     . ARG A 1 152 ? 152.656 153.282 154.084 1.00 21.69  ? 152 ARG A N     1 
ATOM   959  C CA    . ARG A 1 152 ? 152.676 152.246 153.051 1.00 21.69  ? 152 ARG A CA    1 
ATOM   960  C C     . ARG A 1 152 ? 151.328 152.148 152.344 1.00 21.69  ? 152 ARG A C     1 
ATOM   961  O O     . ARG A 1 152 ? 150.762 151.065 152.181 1.00 21.69  ? 152 ARG A O     1 
ATOM   962  C CB    . ARG A 1 152 ? 153.069 150.900 153.651 1.00 21.69  ? 152 ARG A CB    1 
ATOM   963  C CG    . ARG A 1 152 ? 154.497 150.846 154.167 1.00 21.69  ? 152 ARG A CG    1 
ATOM   964  C CD    . ARG A 1 152 ? 154.928 149.419 154.463 1.00 21.69  ? 152 ARG A CD    1 
ATOM   965  N NE    . ARG A 1 152 ? 154.369 148.929 155.717 1.00 21.69  ? 152 ARG A NE    1 
ATOM   966  C CZ    . ARG A 1 152 ? 154.368 147.657 156.090 1.00 21.69  ? 152 ARG A CZ    1 
ATOM   967  N NH1   . ARG A 1 152 ? 154.890 146.712 155.326 1.00 21.69  ? 152 ARG A NH1   1 
ATOM   968  N NH2   . ARG A 1 152 ? 153.826 147.324 157.258 1.00 21.69  ? 152 ARG A NH2   1 
ATOM   969  N N     . ALA A 1 153 ? 150.786 153.298 151.939 1.00 27.80  ? 153 ALA A N     1 
ATOM   970  C CA    . ALA A 1 153 ? 149.565 153.311 151.139 1.00 27.80  ? 153 ALA A CA    1 
ATOM   971  C C     . ALA A 1 153 ? 149.721 152.504 149.857 1.00 27.80  ? 153 ALA A C     1 
ATOM   972  O O     . ALA A 1 153 ? 148.844 151.706 149.507 1.00 27.80  ? 153 ALA A O     1 
ATOM   973  C CB    . ALA A 1 153 ? 149.168 154.752 150.821 1.00 27.80  ? 153 ALA A CB    1 
ATOM   974  N N     . ASP A 1 154 ? 150.839 152.686 149.151 1.00 25.52  ? 154 ASP A N     1 
ATOM   975  C CA    . ASP A 1 154 ? 151.016 152.030 147.859 1.00 25.52  ? 154 ASP A CA    1 
ATOM   976  C C     . ASP A 1 154 ? 151.084 150.512 147.976 1.00 25.52  ? 154 ASP A C     1 
ATOM   977  O O     . ASP A 1 154 ? 150.979 149.819 146.959 1.00 25.52  ? 154 ASP A O     1 
ATOM   978  C CB    . ASP A 1 154 ? 152.266 152.575 147.162 1.00 25.52  ? 154 ASP A CB    1 
ATOM   979  C CG    . ASP A 1 154 ? 153.545 152.293 147.932 1.00 25.52  ? 154 ASP A CG    1 
ATOM   980  O OD1   . ASP A 1 154 ? 153.479 151.710 149.034 1.00 25.52  ? 154 ASP A OD1   1 
ATOM   981  O OD2   . ASP A 1 154 ? 154.627 152.664 147.431 1.00 25.52  ? 154 ASP A OD2   1 
ATOM   982  N N     . GLU A 1 155 ? 151.264 149.985 149.185 1.00 32.02  ? 155 GLU A N     1 
ATOM   983  C CA    . GLU A 1 155 ? 151.203 148.550 149.427 1.00 32.02  ? 155 GLU A CA    1 
ATOM   984  C C     . GLU A 1 155 ? 149.895 148.110 150.066 1.00 32.02  ? 155 GLU A C     1 
ATOM   985  O O     . GLU A 1 155 ? 149.461 146.974 149.846 1.00 32.02  ? 155 GLU A O     1 
ATOM   986  C CB    . GLU A 1 155 ? 152.369 148.114 150.322 1.00 32.02  ? 155 GLU A CB    1 
ATOM   987  C CG    . GLU A 1 155 ? 152.531 146.609 150.449 1.00 32.02  ? 155 GLU A CG    1 
ATOM   988  C CD    . GLU A 1 155 ? 153.867 146.215 151.044 1.00 32.02  ? 155 GLU A CD    1 
ATOM   989  O OE1   . GLU A 1 155 ? 154.870 146.198 150.299 1.00 32.02  ? 155 GLU A OE1   1 
ATOM   990  O OE2   . GLU A 1 155 ? 153.915 145.919 152.256 1.00 32.02  ? 155 GLU A OE2   1 
ATOM   991  N N     . TYR A 1 156 ? 149.254 148.984 150.841 1.00 34.15  ? 156 TYR A N     1 
ATOM   992  C CA    . TYR A 1 156 ? 148.058 148.619 151.590 1.00 34.15  ? 156 TYR A CA    1 
ATOM   993  C C     . TYR A 1 156 ? 146.780 148.789 150.776 1.00 34.15  ? 156 TYR A C     1 
ATOM   994  O O     . TYR A 1 156 ? 145.924 147.900 150.771 1.00 34.15  ? 156 TYR A O     1 
ATOM   995  C CB    . TYR A 1 156 ? 147.979 149.453 152.871 1.00 34.15  ? 156 TYR A CB    1 
ATOM   996  C CG    . TYR A 1 156 ? 146.686 149.296 153.638 1.00 34.15  ? 156 TYR A CG    1 
ATOM   997  C CD1   . TYR A 1 156 ? 146.187 148.041 153.950 1.00 34.15  ? 156 TYR A CD1   1 
ATOM   998  C CD2   . TYR A 1 156 ? 145.969 150.405 154.056 1.00 34.15  ? 156 TYR A CD2   1 
ATOM   999  C CE1   . TYR A 1 156 ? 145.009 147.897 154.651 1.00 34.15  ? 156 TYR A CE1   1 
ATOM   1000 C CE2   . TYR A 1 156 ? 144.791 150.268 154.756 1.00 34.15  ? 156 TYR A CE2   1 
ATOM   1001 C CZ    . TYR A 1 156 ? 144.318 149.015 155.052 1.00 34.15  ? 156 TYR A CZ    1 
ATOM   1002 O OH    . TYR A 1 156 ? 143.145 148.879 155.752 1.00 34.15  ? 156 TYR A OH    1 
ATOM   1003 N N     . TRP A 1 157 ? 146.630 149.918 150.094 1.00 42.14  ? 157 TRP A N     1 
ATOM   1004 C CA    . TRP A 1 157 ? 145.378 150.223 149.414 1.00 42.14  ? 157 TRP A CA    1 
ATOM   1005 C C     . TRP A 1 157 ? 145.198 149.407 148.135 1.00 42.14  ? 157 TRP A C     1 
ATOM   1006 O O     . TRP A 1 157 ? 144.073 148.977 147.843 1.00 42.14  ? 157 TRP A O     1 
ATOM   1007 C CB    . TRP A 1 157 ? 145.286 151.722 149.133 1.00 42.14  ? 157 TRP A CB    1 
ATOM   1008 C CG    . TRP A 1 157 ? 144.878 152.495 150.345 1.00 42.14  ? 157 TRP A CG    1 
ATOM   1009 C CD1   . TRP A 1 157 ? 145.601 153.453 150.989 1.00 42.14  ? 157 TRP A CD1   1 
ATOM   1010 C CD2   . TRP A 1 157 ? 143.652 152.360 151.073 1.00 42.14  ? 157 TRP A CD2   1 
ATOM   1011 N NE1   . TRP A 1 157 ? 144.898 153.932 152.067 1.00 42.14  ? 157 TRP A NE1   1 
ATOM   1012 C CE2   . TRP A 1 157 ? 143.699 153.276 152.141 1.00 42.14  ? 157 TRP A CE2   1 
ATOM   1013 C CE3   . TRP A 1 157 ? 142.517 151.558 150.922 1.00 42.14  ? 157 TRP A CE3   1 
ATOM   1014 C CZ2   . TRP A 1 157 ? 142.657 153.411 153.051 1.00 42.14  ? 157 TRP A CZ2   1 
ATOM   1015 C CZ3   . TRP A 1 157 ? 141.486 151.693 151.826 1.00 42.14  ? 157 TRP A CZ3   1 
ATOM   1016 C CH2   . TRP A 1 157 ? 141.561 152.613 152.876 1.00 42.14  ? 157 TRP A CH2   1 
ATOM   1017 N N     . PRO A 1 158 ? 146.250 149.171 147.339 1.00 35.09  ? 158 PRO A N     1 
ATOM   1018 C CA    . PRO A 1 158 ? 146.116 148.147 146.292 1.00 35.09  ? 158 PRO A CA    1 
ATOM   1019 C C     . PRO A 1 158 ? 145.720 146.796 146.851 1.00 35.09  ? 158 PRO A C     1 
ATOM   1020 O O     . PRO A 1 158 ? 144.941 146.072 146.222 1.00 35.09  ? 158 PRO A O     1 
ATOM   1021 C CB    . PRO A 1 158 ? 147.509 148.122 145.653 1.00 35.09  ? 158 PRO A CB    1 
ATOM   1022 C CG    . PRO A 1 158 ? 148.014 149.493 145.844 1.00 35.09  ? 158 PRO A CG    1 
ATOM   1023 C CD    . PRO A 1 158 ? 147.501 149.937 147.182 1.00 35.09  ? 158 PRO A CD    1 
ATOM   1024 N N     . LEU A 1 159 ? 146.224 146.444 148.036 1.00 35.02  ? 159 LEU A N     1 
ATOM   1025 C CA    . LEU A 1 159 ? 145.810 145.205 148.687 1.00 35.02  ? 159 LEU A CA    1 
ATOM   1026 C C     . LEU A 1 159 ? 144.326 145.234 149.037 1.00 35.02  ? 159 LEU A C     1 
ATOM   1027 O O     . LEU A 1 159 ? 143.616 144.236 148.853 1.00 35.02  ? 159 LEU A O     1 
ATOM   1028 C CB    . LEU A 1 159 ? 146.657 144.972 149.938 1.00 35.02  ? 159 LEU A CB    1 
ATOM   1029 C CG    . LEU A 1 159 ? 146.268 143.823 150.864 1.00 35.02  ? 159 LEU A CG    1 
ATOM   1030 C CD1   . LEU A 1 159 ? 146.269 142.508 150.114 1.00 35.02  ? 159 LEU A CD1   1 
ATOM   1031 C CD2   . LEU A 1 159 ? 147.216 143.770 152.047 1.00 35.02  ? 159 LEU A CD2   1 
ATOM   1032 N N     . VAL A 1 160 ? 143.840 146.372 149.541 1.00 29.39  ? 160 VAL A N     1 
ATOM   1033 C CA    . VAL A 1 160 ? 142.422 146.500 149.867 1.00 29.39  ? 160 VAL A CA    1 
ATOM   1034 C C     . VAL A 1 160 ? 141.574 146.321 148.617 1.00 29.39  ? 160 VAL A C     1 
ATOM   1035 O O     . VAL A 1 160 ? 140.572 145.595 148.624 1.00 29.39  ? 160 VAL A O     1 
ATOM   1036 C CB    . VAL A 1 160 ? 142.151 147.858 150.540 1.00 29.39  ? 160 VAL A CB    1 
ATOM   1037 C CG1   . VAL A 1 160 ? 140.664 148.155 150.560 1.00 29.39  ? 160 VAL A CG1   1 
ATOM   1038 C CG2   . VAL A 1 160 ? 142.713 147.874 151.944 1.00 29.39  ? 160 VAL A CG2   1 
ATOM   1039 N N     . LEU A 1 161 ? 141.966 146.971 147.521 1.00 28.16  ? 161 LEU A N     1 
ATOM   1040 C CA    . LEU A 1 161 ? 141.187 146.867 146.294 1.00 28.16  ? 161 LEU A CA    1 
ATOM   1041 C C     . LEU A 1 161 ? 141.254 145.460 145.711 1.00 28.16  ? 161 LEU A C     1 
ATOM   1042 O O     . LEU A 1 161 ? 140.276 144.979 145.129 1.00 28.16  ? 161 LEU A O     1 
ATOM   1043 C CB    . LEU A 1 161 ? 141.666 147.904 145.282 1.00 28.16  ? 161 LEU A CB    1 
ATOM   1044 C CG    . LEU A 1 161 ? 141.229 149.331 145.611 1.00 28.16  ? 161 LEU A CG    1 
ATOM   1045 C CD1   . LEU A 1 161 ? 142.221 150.338 145.059 1.00 28.16  ? 161 LEU A CD1   1 
ATOM   1046 C CD2   . LEU A 1 161 ? 139.833 149.597 145.084 1.00 28.16  ? 161 LEU A CD2   1 
ATOM   1047 N N     . ASP A 1 162 ? 142.395 144.781 145.857 1.00 33.52  ? 162 ASP A N     1 
ATOM   1048 C CA    . ASP A 1 162 ? 142.492 143.400 145.396 1.00 33.52  ? 162 ASP A CA    1 
ATOM   1049 C C     . ASP A 1 162 ? 141.578 142.483 146.197 1.00 33.52  ? 162 ASP A C     1 
ATOM   1050 O O     . ASP A 1 162 ? 140.910 141.610 145.628 1.00 33.52  ? 162 ASP A O     1 
ATOM   1051 C CB    . ASP A 1 162 ? 143.939 142.918 145.477 1.00 33.52  ? 162 ASP A CB    1 
ATOM   1052 C CG    . ASP A 1 162 ? 144.839 143.615 144.479 1.00 33.52  ? 162 ASP A CG    1 
ATOM   1053 O OD1   . ASP A 1 162 ? 144.312 144.302 143.579 1.00 33.52  ? 162 ASP A OD1   1 
ATOM   1054 O OD2   . ASP A 1 162 ? 146.074 143.476 144.595 1.00 33.52  ? 162 ASP A OD2   1 
ATOM   1055 N N     . ILE A 1 163 ? 141.536 142.661 147.519 1.00 29.46  ? 163 ILE A N     1 
ATOM   1056 C CA    . ILE A 1 163 ? 140.620 141.874 148.340 1.00 29.46  ? 163 ILE A CA    1 
ATOM   1057 C C     . ILE A 1 163 ? 139.178 142.166 147.953 1.00 29.46  ? 163 ILE A C     1 
ATOM   1058 O O     . ILE A 1 163 ? 138.332 141.262 147.901 1.00 29.46  ? 163 ILE A O     1 
ATOM   1059 C CB    . ILE A 1 163 ? 140.880 142.142 149.832 1.00 29.46  ? 163 ILE A CB    1 
ATOM   1060 C CG1   . ILE A 1 163 ? 142.259 141.618 150.217 1.00 29.46  ? 163 ILE A CG1   1 
ATOM   1061 C CG2   . ILE A 1 163 ? 139.806 141.524 150.693 1.00 29.46  ? 163 ILE A CG2   1 
ATOM   1062 C CD1   . ILE A 1 163 ? 142.678 141.999 151.589 1.00 29.46  ? 163 ILE A CD1   1 
ATOM   1063 N N     . ALA A 1 164 ? 138.880 143.433 147.667 1.00 39.85  ? 164 ALA A N     1 
ATOM   1064 C CA    . ALA A 1 164 ? 137.548 143.797 147.204 1.00 39.85  ? 164 ALA A CA    1 
ATOM   1065 C C     . ALA A 1 164 ? 137.204 143.092 145.901 1.00 39.85  ? 164 ALA A C     1 
ATOM   1066 O O     . ALA A 1 164 ? 136.082 142.607 145.725 1.00 39.85  ? 164 ALA A O     1 
ATOM   1067 C CB    . ALA A 1 164 ? 137.464 145.307 147.023 1.00 39.85  ? 164 ALA A CB    1 
ATOM   1068 N N     . GLN A 1 165 ? 138.154 143.045 144.969 1.00 42.84  ? 165 GLN A N     1 
ATOM   1069 C CA    . GLN A 1 165 ? 137.919 142.357 143.706 1.00 42.84  ? 165 GLN A CA    1 
ATOM   1070 C C     . GLN A 1 165 ? 137.669 140.873 143.928 1.00 42.84  ? 165 GLN A C     1 
ATOM   1071 O O     . GLN A 1 165 ? 136.768 140.288 143.317 1.00 42.84  ? 165 GLN A O     1 
ATOM   1072 C CB    . GLN A 1 165 ? 139.110 142.558 142.775 1.00 42.84  ? 165 GLN A CB    1 
ATOM   1073 C CG    . GLN A 1 165 ? 139.164 143.918 142.125 1.00 42.84  ? 165 GLN A CG    1 
ATOM   1074 C CD    . GLN A 1 165 ? 140.334 144.046 141.183 1.00 42.84  ? 165 GLN A CD    1 
ATOM   1075 O OE1   . GLN A 1 165 ? 141.490 144.018 141.602 1.00 42.84  ? 165 GLN A OE1   1 
ATOM   1076 N NE2   . GLN A 1 165 ? 140.043 144.167 139.897 1.00 42.84  ? 165 GLN A NE2   1 
ATOM   1077 N N     . LYS A 1 166 ? 138.457 140.248 144.802 1.00 40.71  ? 166 LYS A N     1 
ATOM   1078 C CA    . LYS A 1 166 ? 138.338 138.810 145.006 1.00 40.71  ? 166 LYS A CA    1 
ATOM   1079 C C     . LYS A 1 166 ? 137.093 138.415 145.790 1.00 40.71  ? 166 LYS A C     1 
ATOM   1080 O O     . LYS A 1 166 ? 136.616 137.289 145.617 1.00 40.71  ? 166 LYS A O     1 
ATOM   1081 C CB    . LYS A 1 166 ? 139.582 138.267 145.711 1.00 40.71  ? 166 LYS A CB    1 
ATOM   1082 C CG    . LYS A 1 166 ? 140.886 138.579 144.999 1.00 40.71  ? 166 LYS A CG    1 
ATOM   1083 C CD    . LYS A 1 166 ? 141.051 137.737 143.746 1.00 40.71  ? 166 LYS A CD    1 
ATOM   1084 C CE    . LYS A 1 166 ? 142.070 138.352 142.801 1.00 40.71  ? 166 LYS A CE    1 
ATOM   1085 N NZ    . LYS A 1 166 ? 142.716 137.330 141.933 1.00 40.71  ? 166 LYS A NZ    1 
ATOM   1086 N N     . ASN A 1 167 ? 136.555 139.291 146.636 1.00 43.12  ? 167 ASN A N     1 
ATOM   1087 C CA    . ASN A 1 167 ? 135.412 138.953 147.477 1.00 43.12  ? 167 ASN A CA    1 
ATOM   1088 C C     . ASN A 1 167 ? 134.203 139.793 147.092 1.00 43.12  ? 167 ASN A C     1 
ATOM   1089 O O     . ASN A 1 167 ? 134.306 141.016 146.967 1.00 43.12  ? 167 ASN A O     1 
ATOM   1090 C CB    . ASN A 1 167 ? 135.757 139.142 148.951 1.00 43.12  ? 167 ASN A CB    1 
ATOM   1091 C CG    . ASN A 1 167 ? 137.000 138.381 149.348 1.00 43.12  ? 167 ASN A CG    1 
ATOM   1092 O OD1   . ASN A 1 167 ? 138.046 138.974 149.611 1.00 43.12  ? 167 ASN A OD1   1 
ATOM   1093 N ND2   . ASN A 1 167 ? 136.893 137.064 149.402 1.00 43.12  ? 167 ASN A ND2   1 
ATOM   1094 N N     . ASN A 1 168 ? 133.057 139.136 146.929 1.00 57.52  ? 168 ASN A N     1 
ATOM   1095 C CA    . ASN A 1 168 ? 131.895 139.783 146.343 1.00 57.52  ? 168 ASN A CA    1 
ATOM   1096 C C     . ASN A 1 168 ? 131.118 140.592 147.384 1.00 57.52  ? 168 ASN A C     1 
ATOM   1097 O O     . ASN A 1 168 ? 131.399 140.568 148.592 1.00 57.52  ? 168 ASN A O     1 
ATOM   1098 C CB    . ASN A 1 168 ? 130.983 138.749 145.685 1.00 57.52  ? 168 ASN A CB    1 
ATOM   1099 C CG    . ASN A 1 168 ? 130.165 137.972 146.690 1.00 57.52  ? 168 ASN A CG    1 
ATOM   1100 O OD1   . ASN A 1 168 ? 129.000 138.283 146.930 1.00 57.52  ? 168 ASN A OD1   1 
ATOM   1101 N ND2   . ASN A 1 168 ? 130.771 136.953 147.286 1.00 57.52  ? 168 ASN A ND2   1 
ATOM   1102 N N     . LEU A 1 169 ? 130.117 141.320 146.881 1.00 51.52  ? 169 LEU A N     1 
ATOM   1103 C CA    . LEU A 1 169 ? 129.370 142.254 147.715 1.00 51.52  ? 169 LEU A CA    1 
ATOM   1104 C C     . LEU A 1 169 ? 128.586 141.541 148.805 1.00 51.52  ? 169 LEU A C     1 
ATOM   1105 O O     . LEU A 1 169 ? 128.530 142.015 149.941 1.00 51.52  ? 169 LEU A O     1 
ATOM   1106 C CB    . LEU A 1 169 ? 128.427 143.097 146.861 1.00 51.52  ? 169 LEU A CB    1 
ATOM   1107 C CG    . LEU A 1 169 ? 127.896 144.290 147.653 1.00 51.52  ? 169 LEU A CG    1 
ATOM   1108 C CD1   . LEU A 1 169 ? 129.047 145.072 148.262 1.00 51.52  ? 169 LEU A CD1   1 
ATOM   1109 C CD2   . LEU A 1 169 ? 127.019 145.175 146.789 1.00 51.52  ? 169 LEU A CD2   1 
ATOM   1110 N N     . LYS A 1 170 ? 127.938 140.424 148.473 1.00 59.68  ? 170 LYS A N     1 
ATOM   1111 C CA    . LYS A 1 170 ? 127.167 139.708 149.484 1.00 59.68  ? 170 LYS A CA    1 
ATOM   1112 C C     . LYS A 1 170 ? 128.068 139.216 150.609 1.00 59.68  ? 170 LYS A C     1 
ATOM   1113 O O     . LYS A 1 170 ? 127.713 139.306 151.792 1.00 59.68  ? 170 LYS A O     1 
ATOM   1114 C CB    . LYS A 1 170 ? 126.410 138.543 148.846 1.00 59.68  ? 170 LYS A CB    1 
ATOM   1115 C CG    . LYS A 1 170 ? 125.610 138.927 147.613 1.00 59.68  ? 170 LYS A CG    1 
ATOM   1116 C CD    . LYS A 1 170 ? 125.081 137.699 146.889 1.00 59.68  ? 170 LYS A CD    1 
ATOM   1117 C CE    . LYS A 1 170 ? 124.259 138.089 145.671 1.00 59.68  ? 170 LYS A CE    1 
ATOM   1118 N NZ    . LYS A 1 170 ? 123.127 138.985 146.031 1.00 59.68  ? 170 LYS A NZ    1 
ATOM   1119 N N     . ARG A 1 171 ? 129.247 138.701 150.257 1.00 60.57  ? 171 ARG A N     1 
ATOM   1120 C CA    . ARG A 1 171 ? 130.187 138.244 151.272 1.00 60.57  ? 171 ARG A CA    1 
ATOM   1121 C C     . ARG A 1 171 ? 130.651 139.400 152.148 1.00 60.57  ? 171 ARG A C     1 
ATOM   1122 O O     . ARG A 1 171 ? 130.781 139.252 153.369 1.00 60.57  ? 171 ARG A O     1 
ATOM   1123 C CB    . ARG A 1 171 ? 131.378 137.550 150.613 1.00 60.57  ? 171 ARG A CB    1 
ATOM   1124 C CG    . ARG A 1 171 ? 132.486 137.199 151.582 1.00 60.57  ? 171 ARG A CG    1 
ATOM   1125 C CD    . ARG A 1 171 ? 133.007 135.798 151.340 1.00 60.57  ? 171 ARG A CD    1 
ATOM   1126 N NE    . ARG A 1 171 ? 133.878 135.360 152.422 1.00 60.57  ? 171 ARG A NE    1 
ATOM   1127 C CZ    . ARG A 1 171 ? 133.449 134.850 153.568 1.00 60.57  ? 171 ARG A CZ    1 
ATOM   1128 N NH1   . ARG A 1 171 ? 132.159 134.690 153.813 1.00 60.57  ? 171 ARG A NH1   1 
ATOM   1129 N NH2   . ARG A 1 171 ? 134.336 134.493 154.491 1.00 60.57  ? 171 ARG A NH2   1 
ATOM   1130 N N     . ILE A 1 172 ? 130.908 140.563 151.546 1.00 48.87  ? 172 ILE A N     1 
ATOM   1131 C CA    . ILE A 1 172 ? 131.318 141.702 152.366 1.00 48.87  ? 172 ILE A CA    1 
ATOM   1132 C C     . ILE A 1 172 ? 130.166 142.188 153.247 1.00 48.87  ? 172 ILE A C     1 
ATOM   1133 O O     . ILE A 1 172 ? 130.386 142.608 154.391 1.00 48.87  ? 172 ILE A O     1 
ATOM   1134 C CB    . ILE A 1 172 ? 131.886 142.829 151.488 1.00 48.87  ? 172 ILE A CB    1 
ATOM   1135 C CG1   . ILE A 1 172 ? 133.074 142.315 150.678 1.00 48.87  ? 172 ILE A CG1   1 
ATOM   1136 C CG2   . ILE A 1 172 ? 132.352 143.976 152.355 1.00 48.87  ? 172 ILE A CG2   1 
ATOM   1137 C CD1   . ILE A 1 172 ? 134.237 141.865 151.528 1.00 48.87  ? 172 ILE A CD1   1 
ATOM   1138 N N     . ILE A 1 173 ? 128.929 142.142 152.740 1.00 56.50  ? 173 ILE A N     1 
ATOM   1139 C CA    . ILE A 1 173 ? 127.749 142.412 153.561 1.00 56.50  ? 173 ILE A CA    1 
ATOM   1140 C C     . ILE A 1 173 ? 127.715 141.497 154.771 1.00 56.50  ? 173 ILE A C     1 
ATOM   1141 O O     . ILE A 1 173 ? 127.432 141.943 155.890 1.00 56.50  ? 173 ILE A O     1 
ATOM   1142 C CB    . ILE A 1 173 ? 126.455 142.249 152.738 1.00 56.50  ? 173 ILE A CB    1 
ATOM   1143 C CG1   . ILE A 1 173 ? 126.334 143.302 151.642 1.00 56.50  ? 173 ILE A CG1   1 
ATOM   1144 C CG2   . ILE A 1 173 ? 125.234 142.309 153.644 1.00 56.50  ? 173 ILE A CG2   1 
ATOM   1145 C CD1   . ILE A 1 173 ? 126.141 144.684 152.173 1.00 56.50  ? 173 ILE A CD1   1 
ATOM   1146 N N     . ARG A 1 174 ? 128.011 140.211 154.576 1.00 74.93  ? 174 ARG A N     1 
ATOM   1147 C CA    . ARG A 1 174 ? 127.810 139.232 155.635 1.00 74.93  ? 174 ARG A CA    1 
ATOM   1148 C C     . ARG A 1 174 ? 128.705 139.483 156.842 1.00 74.93  ? 174 ARG A C     1 
ATOM   1149 O O     . ARG A 1 174 ? 128.463 138.905 157.906 1.00 74.93  ? 174 ARG A O     1 
ATOM   1150 C CB    . ARG A 1 174 ? 128.034 137.829 155.078 1.00 74.93  ? 174 ARG A CB    1 
ATOM   1151 C CG    . ARG A 1 174 ? 126.744 137.127 154.704 1.00 74.93  ? 174 ARG A CG    1 
ATOM   1152 C CD    . ARG A 1 174 ? 127.014 135.759 154.126 1.00 74.93  ? 174 ARG A CD    1 
ATOM   1153 N NE    . ARG A 1 174 ? 126.997 135.779 152.669 1.00 74.93  ? 174 ARG A NE    1 
ATOM   1154 C CZ    . ARG A 1 174 ? 128.048 135.514 151.906 1.00 74.93  ? 174 ARG A CZ    1 
ATOM   1155 N NH1   . ARG A 1 174 ? 129.219 135.194 152.432 1.00 74.93  ? 174 ARG A NH1   1 
ATOM   1156 N NH2   . ARG A 1 174 ? 127.922 135.574 150.584 1.00 74.93  ? 174 ARG A NH2   1 
ATOM   1157 N N     . CYS A 1 175 ? 129.726 140.330 156.708 1.00 63.92  ? 175 CYS A N     1 
ATOM   1158 C CA    . CYS A 1 175 ? 130.520 140.775 157.853 1.00 63.92  ? 175 CYS A CA    1 
ATOM   1159 C C     . CYS A 1 175 ? 129.857 142.014 158.461 1.00 63.92  ? 175 CYS A C     1 
ATOM   1160 O O     . CYS A 1 175 ? 130.376 143.132 158.424 1.00 63.92  ? 175 CYS A O     1 
ATOM   1161 C CB    . CYS A 1 175 ? 131.955 141.053 157.430 1.00 63.92  ? 175 CYS A CB    1 
ATOM   1162 S SG    . CYS A 1 175 ? 132.799 139.636 156.693 1.00 63.92  ? 175 CYS A SG    1 
ATOM   1163 N N     . SER A 1 176 ? 128.673 141.792 159.039 1.00 84.43  ? 176 SER A N     1 
ATOM   1164 C CA    . SER A 1 176 ? 127.818 142.883 159.488 1.00 84.43  ? 176 SER A CA    1 
ATOM   1165 C C     . SER A 1 176 ? 127.693 143.008 161.000 1.00 84.43  ? 176 SER A C     1 
ATOM   1166 O O     . SER A 1 176 ? 127.572 144.132 161.496 1.00 84.43  ? 176 SER A O     1 
ATOM   1167 C CB    . SER A 1 176 ? 126.410 142.732 158.895 1.00 84.43  ? 176 SER A CB    1 
ATOM   1168 O OG    . SER A 1 176 ? 125.796 141.534 159.336 1.00 84.43  ? 176 SER A OG    1 
ATOM   1169 N N     . GLN A 1 177 ? 127.725 141.902 161.741 1.00 96.64  ? 177 GLN A N     1 
ATOM   1170 C CA    . GLN A 1 177 ? 127.482 141.939 163.178 1.00 96.64  ? 177 GLN A CA    1 
ATOM   1171 C C     . GLN A 1 177 ? 128.717 142.313 163.987 1.00 96.64  ? 177 GLN A C     1 
ATOM   1172 O O     . GLN A 1 177 ? 128.643 142.341 165.220 1.00 96.64  ? 177 GLN A O     1 
ATOM   1173 C CB    . GLN A 1 177 ? 126.937 140.591 163.667 1.00 96.64  ? 177 GLN A CB    1 
ATOM   1174 C CG    . GLN A 1 177 ? 127.779 139.390 163.285 1.00 96.64  ? 177 GLN A CG    1 
ATOM   1175 C CD    . GLN A 1 177 ? 127.179 138.081 163.764 1.00 96.64  ? 177 GLN A CD    1 
ATOM   1176 O OE1   . GLN A 1 177 ? 126.113 137.669 163.307 1.00 96.64  ? 177 GLN A OE1   1 
ATOM   1177 N NE2   . GLN A 1 177 ? 127.861 137.421 164.693 1.00 96.64  ? 177 GLN A NE2   1 
ATOM   1178 N N     . ILE A 1 178 ? 129.850 142.586 163.334 1.00 88.63  ? 178 ILE A N     1 
ATOM   1179 C CA    . ILE A 1 178 ? 131.012 143.087 164.059 1.00 88.63  ? 178 ILE A CA    1 
ATOM   1180 C C     . ILE A 1 178 ? 130.743 144.458 164.663 1.00 88.63  ? 178 ILE A C     1 
ATOM   1181 O O     . ILE A 1 178 ? 131.346 144.811 165.684 1.00 88.63  ? 178 ILE A O     1 
ATOM   1182 C CB    . ILE A 1 178 ? 132.246 143.133 163.139 1.00 88.63  ? 178 ILE A CB    1 
ATOM   1183 C CG1   . ILE A 1 178 ? 131.953 143.958 161.887 1.00 88.63  ? 178 ILE A CG1   1 
ATOM   1184 C CG2   . ILE A 1 178 ? 132.681 141.735 162.748 1.00 88.63  ? 178 ILE A CG2   1 
ATOM   1185 C CD1   . ILE A 1 178 ? 133.095 143.971 160.906 1.00 88.63  ? 178 ILE A CD1   1 
ATOM   1186 N N     . MET A 1 179 ? 129.851 145.244 164.058 1.00 90.61  ? 179 MET A N     1 
ATOM   1187 C CA    . MET A 1 179 ? 129.440 146.527 164.610 1.00 90.61  ? 179 MET A CA    1 
ATOM   1188 C C     . MET A 1 179 ? 128.149 146.444 165.414 1.00 90.61  ? 179 MET A C     1 
ATOM   1189 O O     . MET A 1 179 ? 127.742 147.449 166.007 1.00 90.61  ? 179 MET A O     1 
ATOM   1190 C CB    . MET A 1 179 ? 129.292 147.559 163.485 1.00 90.61  ? 179 MET A CB    1 
ATOM   1191 C CG    . MET A 1 179 ? 130.611 147.935 162.814 1.00 90.61  ? 179 MET A CG    1 
ATOM   1192 S SD    . MET A 1 179 ? 130.438 149.143 161.488 1.00 90.61  ? 179 MET A SD    1 
ATOM   1193 C CE    . MET A 1 179 ? 132.126 149.256 160.898 1.00 90.61  ? 179 MET A CE    1 
ATOM   1194 N N     . GLY A 1 180 ? 127.501 145.282 165.455 1.00 111.69 ? 180 GLY A N     1 
ATOM   1195 C CA    . GLY A 1 180 ? 126.307 145.104 166.258 1.00 111.69 ? 180 GLY A CA    1 
ATOM   1196 C C     . GLY A 1 180 ? 125.014 145.465 165.556 1.00 111.69 ? 180 GLY A C     1 
ATOM   1197 O O     . GLY A 1 180 ? 124.216 146.247 166.084 1.00 111.69 ? 180 GLY A O     1 
ATOM   1198 N N     . ARG A 1 181 ? 124.790 144.904 164.367 1.00 109.96 ? 181 ARG A N     1 
ATOM   1199 C CA    . ARG A 1 181 ? 123.557 145.126 163.622 1.00 109.96 ? 181 ARG A CA    1 
ATOM   1200 C C     . ARG A 1 181 ? 123.077 143.815 163.013 1.00 109.96 ? 181 ARG A C     1 
ATOM   1201 O O     . ARG A 1 181 ? 123.822 142.836 162.927 1.00 109.96 ? 181 ARG A O     1 
ATOM   1202 C CB    . ARG A 1 181 ? 123.732 146.182 162.519 1.00 109.96 ? 181 ARG A CB    1 
ATOM   1203 C CG    . ARG A 1 181 ? 124.103 147.563 163.027 1.00 109.96 ? 181 ARG A CG    1 
ATOM   1204 C CD    . ARG A 1 181 ? 124.549 148.480 161.902 1.00 109.96 ? 181 ARG A CD    1 
ATOM   1205 N NE    . ARG A 1 181 ? 125.168 149.695 162.416 1.00 109.96 ? 181 ARG A NE    1 
ATOM   1206 C CZ    . ARG A 1 181 ? 125.173 150.860 161.784 1.00 109.96 ? 181 ARG A CZ    1 
ATOM   1207 N NH1   . ARG A 1 181 ? 124.578 151.013 160.612 1.00 109.96 ? 181 ARG A NH1   1 
ATOM   1208 N NH2   . ARG A 1 181 ? 125.779 151.901 162.347 1.00 109.96 ? 181 ARG A NH2   1 
ATOM   1209 N N     . SER A 1 182 ? 121.816 143.808 162.586 1.00 118.51 ? 182 SER A N     1 
ATOM   1210 C CA    . SER A 1 182 ? 121.209 142.636 161.971 1.00 118.51 ? 182 SER A CA    1 
ATOM   1211 C C     . SER A 1 182 ? 121.455 142.629 160.466 1.00 118.51 ? 182 SER A C     1 
ATOM   1212 O O     . SER A 1 182 ? 121.821 143.642 159.864 1.00 118.51 ? 182 SER A O     1 
ATOM   1213 C CB    . SER A 1 182 ? 119.704 142.577 162.255 1.00 118.51 ? 182 SER A CB    1 
ATOM   1214 O OG    . SER A 1 182 ? 118.998 143.568 161.529 1.00 118.51 ? 182 SER A OG    1 
ATOM   1215 N N     . GLU A 1 183 ? 121.250 141.455 159.864 1.00 109.33 ? 183 GLU A N     1 
ATOM   1216 C CA    . GLU A 1 183 ? 121.531 141.291 158.441 1.00 109.33 ? 183 GLU A CA    1 
ATOM   1217 C C     . GLU A 1 183 ? 120.570 142.107 157.583 1.00 109.33 ? 183 GLU A C     1 
ATOM   1218 O O     . GLU A 1 183 ? 120.974 142.692 156.571 1.00 109.33 ? 183 GLU A O     1 
ATOM   1219 C CB    . GLU A 1 183 ? 121.463 139.812 158.061 1.00 109.33 ? 183 GLU A CB    1 
ATOM   1220 C CG    . GLU A 1 183 ? 122.065 139.495 156.703 1.00 109.33 ? 183 GLU A CG    1 
ATOM   1221 C CD    . GLU A 1 183 ? 123.577 139.591 156.701 1.00 109.33 ? 183 GLU A CD    1 
ATOM   1222 O OE1   . GLU A 1 183 ? 124.195 139.304 157.748 1.00 109.33 ? 183 GLU A OE1   1 
ATOM   1223 O OE2   . GLU A 1 183 ? 124.149 139.953 155.653 1.00 109.33 ? 183 GLU A OE2   1 
ATOM   1224 N N     . GLN A 1 184 ? 119.294 142.159 157.972 1.00 117.99 ? 184 GLN A N     1 
ATOM   1225 C CA    . GLN A 1 184 ? 118.285 142.813 157.145 1.00 117.99 ? 184 GLN A CA    1 
ATOM   1226 C C     . GLN A 1 184 ? 118.435 144.330 157.121 1.00 117.99 ? 184 GLN A C     1 
ATOM   1227 O O     . GLN A 1 184 ? 117.799 144.987 156.289 1.00 117.99 ? 184 GLN A O     1 
ATOM   1228 C CB    . GLN A 1 184 ? 116.884 142.438 157.631 1.00 117.99 ? 184 GLN A CB    1 
ATOM   1229 C CG    . GLN A 1 184 ? 116.696 140.952 157.891 1.00 117.99 ? 184 GLN A CG    1 
ATOM   1230 C CD    . GLN A 1 184 ? 116.903 140.111 156.647 1.00 117.99 ? 184 GLN A CD    1 
ATOM   1231 O OE1   . GLN A 1 184 ? 116.516 140.502 155.545 1.00 117.99 ? 184 GLN A OE1   1 
ATOM   1232 N NE2   . GLN A 1 184 ? 117.522 138.949 156.816 1.00 117.99 ? 184 GLN A NE2   1 
ATOM   1233 N N     . ASP A 1 185 ? 119.252 144.900 158.003 1.00 107.61 ? 185 ASP A N     1 
ATOM   1234 C CA    . ASP A 1 185 ? 119.409 146.345 158.051 1.00 107.61 ? 185 ASP A CA    1 
ATOM   1235 C C     . ASP A 1 185 ? 120.178 146.845 156.828 1.00 107.61 ? 185 ASP A C     1 
ATOM   1236 O O     . ASP A 1 185 ? 120.765 146.074 156.063 1.00 107.61 ? 185 ASP A O     1 
ATOM   1237 C CB    . ASP A 1 185 ? 120.121 146.766 159.336 1.00 107.61 ? 185 ASP A CB    1 
ATOM   1238 C CG    . ASP A 1 185 ? 119.310 146.458 160.579 1.00 107.61 ? 185 ASP A CG    1 
ATOM   1239 O OD1   . ASP A 1 185 ? 118.115 146.123 160.442 1.00 107.61 ? 185 ASP A OD1   1 
ATOM   1240 O OD2   . ASP A 1 185 ? 119.866 146.554 161.693 1.00 107.61 ? 185 ASP A OD2   1 
ATOM   1241 N N     . GLU A 1 186 ? 120.171 148.164 156.653 1.00 75.35  ? 186 GLU A N     1 
ATOM   1242 C CA    . GLU A 1 186 ? 120.825 148.821 155.530 1.00 75.35  ? 186 GLU A CA    1 
ATOM   1243 C C     . GLU A 1 186 ? 122.133 149.441 155.997 1.00 75.35  ? 186 GLU A C     1 
ATOM   1244 O O     . GLU A 1 186 ? 122.163 150.156 157.005 1.00 75.35  ? 186 GLU A O     1 
ATOM   1245 C CB    . GLU A 1 186 ? 119.924 149.892 154.914 1.00 75.35  ? 186 GLU A CB    1 
ATOM   1246 C CG    . GLU A 1 186 ? 120.470 150.488 153.627 1.00 75.35  ? 186 GLU A CG    1 
ATOM   1247 C CD    . GLU A 1 186 ? 119.483 151.417 152.951 1.00 75.35  ? 186 GLU A CD    1 
ATOM   1248 O OE1   . GLU A 1 186 ? 119.294 152.547 153.447 1.00 75.35  ? 186 GLU A OE1   1 
ATOM   1249 O OE2   . GLU A 1 186 ? 118.896 151.017 151.923 1.00 75.35  ? 186 GLU A OE2   1 
ATOM   1250 N N     . LEU A 1 187 ? 123.204 149.169 155.262 1.00 51.49  ? 187 LEU A N     1 
ATOM   1251 C CA    . LEU A 1 187 ? 124.540 149.628 155.603 1.00 51.49  ? 187 LEU A CA    1 
ATOM   1252 C C     . LEU A 1 187 ? 124.906 150.854 154.777 1.00 51.49  ? 187 LEU A C     1 
ATOM   1253 O O     . LEU A 1 187 ? 124.267 151.169 153.771 1.00 51.49  ? 187 LEU A O     1 
ATOM   1254 C CB    . LEU A 1 187 ? 125.573 148.521 155.367 1.00 51.49  ? 187 LEU A CB    1 
ATOM   1255 C CG    . LEU A 1 187 ? 125.700 147.381 156.381 1.00 51.49  ? 187 LEU A CG    1 
ATOM   1256 C CD1   . LEU A 1 187 ? 124.506 146.439 156.316 1.00 51.49  ? 187 LEU A CD1   1 
ATOM   1257 C CD2   . LEU A 1 187 ? 126.997 146.618 156.162 1.00 51.49  ? 187 LEU A CD2   1 
ATOM   1258 N N     . THR A 1 188 ? 125.937 151.556 155.228 1.00 41.47  ? 188 THR A N     1 
ATOM   1259 C CA    . THR A 1 188 ? 126.558 152.600 154.432 1.00 41.47  ? 188 THR A CA    1 
ATOM   1260 C C     . THR A 1 188 ? 127.767 152.033 153.697 1.00 41.47  ? 188 THR A C     1 
ATOM   1261 O O     . THR A 1 188 ? 128.299 150.979 154.051 1.00 41.47  ? 188 THR A O     1 
ATOM   1262 C CB    . THR A 1 188 ? 126.974 153.783 155.305 1.00 41.47  ? 188 THR A CB    1 
ATOM   1263 O OG1   . THR A 1 188 ? 127.667 153.306 156.463 1.00 41.47  ? 188 THR A OG1   1 
ATOM   1264 C CG2   . THR A 1 188 ? 125.752 154.570 155.744 1.00 41.47  ? 188 THR A CG2   1 
ATOM   1265 N N     . ALA A 1 189 ? 128.196 152.744 152.652 1.00 35.08  ? 189 ALA A N     1 
ATOM   1266 C CA    . ALA A 1 189 ? 129.314 152.256 151.852 1.00 35.08  ? 189 ALA A CA    1 
ATOM   1267 C C     . ALA A 1 189 ? 130.597 152.161 152.669 1.00 35.08  ? 189 ALA A C     1 
ATOM   1268 O O     . ALA A 1 189 ? 131.482 151.366 152.335 1.00 35.08  ? 189 ALA A O     1 
ATOM   1269 C CB    . ALA A 1 189 ? 129.522 153.149 150.631 1.00 35.08  ? 189 ALA A CB    1 
ATOM   1270 N N     . ALA A 1 190 ? 130.722 152.958 153.734 1.00 37.96  ? 190 ALA A N     1 
ATOM   1271 C CA    . ALA A 1 190 ? 131.856 152.793 154.639 1.00 37.96  ? 190 ALA A CA    1 
ATOM   1272 C C     . ALA A 1 190 ? 131.777 151.476 155.394 1.00 37.96  ? 190 ALA A C     1 
ATOM   1273 O O     . ALA A 1 190 ? 132.811 150.903 155.749 1.00 37.96  ? 190 ALA A O     1 
ATOM   1274 C CB    . ALA A 1 190 ? 131.930 153.952 155.628 1.00 37.96  ? 190 ALA A CB    1 
ATOM   1275 N N     . GLN A 1 191 ? 130.571 150.978 155.641 1.00 49.85  ? 191 GLN A N     1 
ATOM   1276 C CA    . GLN A 1 191 ? 130.405 149.690 156.298 1.00 49.85  ? 191 GLN A CA    1 
ATOM   1277 C C     . GLN A 1 191 ? 130.694 148.529 155.358 1.00 49.85  ? 191 GLN A C     1 
ATOM   1278 O O     . GLN A 1 191 ? 130.699 147.376 155.799 1.00 49.85  ? 191 GLN A O     1 
ATOM   1279 C CB    . GLN A 1 191 ? 128.989 149.584 156.863 1.00 49.85  ? 191 GLN A CB    1 
ATOM   1280 C CG    . GLN A 1 191 ? 128.672 150.678 157.872 1.00 49.85  ? 191 GLN A CG    1 
ATOM   1281 C CD    . GLN A 1 191 ? 127.766 150.221 158.994 1.00 49.85  ? 191 GLN A CD    1 
ATOM   1282 O OE1   . GLN A 1 191 ? 128.041 150.464 160.167 1.00 49.85  ? 191 GLN A OE1   1 
ATOM   1283 N NE2   . GLN A 1 191 ? 126.667 149.567 158.637 1.00 49.85  ? 191 GLN A NE2   1 
ATOM   1284 N N     . ILE A 1 192 ? 130.927 148.814 154.079 1.00 40.34  ? 192 ILE A N     1 
ATOM   1285 C CA    . ILE A 1 192 ? 131.519 147.858 153.163 1.00 40.34  ? 192 ILE A CA    1 
ATOM   1286 C C     . ILE A 1 192 ? 133.008 148.109 152.954 1.00 40.34  ? 192 ILE A C     1 
ATOM   1287 O O     . ILE A 1 192 ? 133.765 147.152 152.756 1.00 40.34  ? 192 ILE A O     1 
ATOM   1288 C CB    . ILE A 1 192 ? 130.760 147.873 151.821 1.00 40.34  ? 192 ILE A CB    1 
ATOM   1289 C CG1   . ILE A 1 192 ? 129.316 147.473 152.078 1.00 40.34  ? 192 ILE A CG1   1 
ATOM   1290 C CG2   . ILE A 1 192 ? 131.402 146.965 150.797 1.00 40.34  ? 192 ILE A CG2   1 
ATOM   1291 C CD1   . ILE A 1 192 ? 129.220 146.116 152.714 1.00 40.34  ? 192 ILE A CD1   1 
ATOM   1292 N N     . PHE A 1 193 ? 133.451 149.363 153.031 1.00 38.57  ? 193 PHE A N     1 
ATOM   1293 C CA    . PHE A 1 193 ? 134.876 149.659 152.976 1.00 38.57  ? 193 PHE A CA    1 
ATOM   1294 C C     . PHE A 1 193 ? 135.607 149.002 154.140 1.00 38.57  ? 193 PHE A C     1 
ATOM   1295 O O     . PHE A 1 193 ? 136.667 148.396 153.960 1.00 38.57  ? 193 PHE A O     1 
ATOM   1296 C CB    . PHE A 1 193 ? 135.083 151.170 153.024 1.00 38.57  ? 193 PHE A CB    1 
ATOM   1297 C CG    . PHE A 1 193 ? 135.237 151.808 151.681 1.00 38.57  ? 193 PHE A CG    1 
ATOM   1298 C CD1   . PHE A 1 193 ? 134.217 151.718 150.752 1.00 38.57  ? 193 PHE A CD1   1 
ATOM   1299 C CD2   . PHE A 1 193 ? 136.377 152.514 151.351 1.00 38.57  ? 193 PHE A CD2   1 
ATOM   1300 C CE1   . PHE A 1 193 ? 134.332 152.311 149.518 1.00 38.57  ? 193 PHE A CE1   1 
ATOM   1301 C CE2   . PHE A 1 193 ? 136.501 153.110 150.117 1.00 38.57  ? 193 PHE A CE2   1 
ATOM   1302 C CZ    . PHE A 1 193 ? 135.473 153.010 149.198 1.00 38.57  ? 193 PHE A CZ    1 
ATOM   1303 N N     . TYR A 1 194 ? 135.032 149.102 155.341 1.00 43.60  ? 194 TYR A N     1 
ATOM   1304 C CA    . TYR A 1 194 ? 135.700 148.662 156.565 1.00 43.60  ? 194 TYR A CA    1 
ATOM   1305 C C     . TYR A 1 194 ? 136.030 147.173 156.597 1.00 43.60  ? 194 TYR A C     1 
ATOM   1306 O O     . TYR A 1 194 ? 137.144 146.826 157.027 1.00 43.60  ? 194 TYR A O     1 
ATOM   1307 C CB    . TYR A 1 194 ? 134.842 149.068 157.768 1.00 43.60  ? 194 TYR A CB    1 
ATOM   1308 C CG    . TYR A 1 194 ? 135.368 148.610 159.108 1.00 43.60  ? 194 TYR A CG    1 
ATOM   1309 C CD1   . TYR A 1 194 ? 136.348 149.330 159.775 1.00 43.60  ? 194 TYR A CD1   1 
ATOM   1310 C CD2   . TYR A 1 194 ? 134.870 147.463 159.714 1.00 43.60  ? 194 TYR A CD2   1 
ATOM   1311 C CE1   . TYR A 1 194 ? 136.823 148.916 161.005 1.00 43.60  ? 194 TYR A CE1   1 
ATOM   1312 C CE2   . TYR A 1 194 ? 135.338 147.043 160.945 1.00 43.60  ? 194 TYR A CE2   1 
ATOM   1313 C CZ    . TYR A 1 194 ? 136.314 147.774 161.586 1.00 43.60  ? 194 TYR A CZ    1 
ATOM   1314 O OH    . TYR A 1 194 ? 136.787 147.361 162.810 1.00 43.60  ? 194 TYR A OH    1 
ATOM   1315 N N     . PRO A 1 195 ? 135.130 146.251 156.224 1.00 35.20  ? 195 PRO A N     1 
ATOM   1316 C CA    . PRO A 1 195 ? 135.522 144.831 156.252 1.00 35.20  ? 195 PRO A CA    1 
ATOM   1317 C C     . PRO A 1 195 ? 136.741 144.532 155.401 1.00 35.20  ? 195 PRO A C     1 
ATOM   1318 O O     . PRO A 1 195 ? 137.594 143.737 155.810 1.00 35.20  ? 195 PRO A O     1 
ATOM   1319 C CB    . PRO A 1 195 ? 134.270 144.116 155.730 1.00 35.20  ? 195 PRO A CB    1 
ATOM   1320 C CG    . PRO A 1 195 ? 133.160 145.020 156.086 1.00 35.20  ? 195 PRO A CG    1 
ATOM   1321 C CD    . PRO A 1 195 ? 133.702 146.403 155.898 1.00 35.20  ? 195 PRO A CD    1 
ATOM   1322 N N     . CYS A 1 196 ? 136.863 145.169 154.235 1.00 32.20  ? 196 CYS A N     1 
ATOM   1323 C CA    . CYS A 1 196 ? 138.035 144.944 153.396 1.00 32.20  ? 196 CYS A CA    1 
ATOM   1324 C C     . CYS A 1 196 ? 139.288 145.541 154.022 1.00 32.20  ? 196 CYS A C     1 
ATOM   1325 O O     . CYS A 1 196 ? 140.376 144.971 153.902 1.00 32.20  ? 196 CYS A O     1 
ATOM   1326 C CB    . CYS A 1 196 ? 137.800 145.516 152.001 1.00 32.20  ? 196 CYS A CB    1 
ATOM   1327 S SG    . CYS A 1 196 ? 136.470 144.705 151.093 1.00 32.20  ? 196 CYS A SG    1 
ATOM   1328 N N     . MET A 1 197 ? 139.161 146.685 154.699 1.00 31.72  ? 197 MET A N     1 
ATOM   1329 C CA    . MET A 1 197 ? 140.315 147.258 155.384 1.00 31.72  ? 197 MET A CA    1 
ATOM   1330 C C     . MET A 1 197 ? 140.797 146.344 156.508 1.00 31.72  ? 197 MET A C     1 
ATOM   1331 O O     . MET A 1 197 ? 142.005 146.125 156.666 1.00 31.72  ? 197 MET A O     1 
ATOM   1332 C CB    . MET A 1 197 ? 139.974 148.652 155.913 1.00 31.72  ? 197 MET A CB    1 
ATOM   1333 C CG    . MET A 1 197 ? 139.341 149.555 154.865 1.00 31.72  ? 197 MET A CG    1 
ATOM   1334 S SD    . MET A 1 197 ? 139.017 151.248 155.392 1.00 31.72  ? 197 MET A SD    1 
ATOM   1335 C CE    . MET A 1 197 ? 140.614 151.731 156.034 1.00 31.72  ? 197 MET A CE    1 
ATOM   1336 N N     . GLN A 1 198 ? 139.867 145.784 157.285 1.00 37.39  ? 198 GLN A N     1 
ATOM   1337 C CA    . GLN A 1 198 ? 140.252 144.801 158.296 1.00 37.39  ? 198 GLN A CA    1 
ATOM   1338 C C     . GLN A 1 198 ? 140.882 143.566 157.662 1.00 37.39  ? 198 GLN A C     1 
ATOM   1339 O O     . GLN A 1 198 ? 141.899 143.062 158.150 1.00 37.39  ? 198 GLN A O     1 
ATOM   1340 C CB    . GLN A 1 198 ? 139.042 144.399 159.138 1.00 37.39  ? 198 GLN A CB    1 
ATOM   1341 C CG    . GLN A 1 198 ? 138.370 145.529 159.889 1.00 37.39  ? 198 GLN A CG    1 
ATOM   1342 C CD    . GLN A 1 198 ? 138.824 145.592 161.334 1.00 37.39  ? 198 GLN A CD    1 
ATOM   1343 O OE1   . GLN A 1 198 ? 138.816 144.585 162.039 1.00 37.39  ? 198 GLN A OE1   1 
ATOM   1344 N NE2   . GLN A 1 198 ? 139.214 146.774 161.784 1.00 37.39  ? 198 GLN A NE2   1 
ATOM   1345 N N     . CYS A 1 199 ? 140.291 143.065 156.575 1.00 30.17  ? 199 CYS A N     1 
ATOM   1346 C CA    . CYS A 1 199 ? 140.824 141.881 155.910 1.00 30.17  ? 199 CYS A CA    1 
ATOM   1347 C C     . CYS A 1 199 ? 142.219 142.124 155.353 1.00 30.17  ? 199 CYS A C     1 
ATOM   1348 O O     . CYS A 1 199 ? 143.022 141.191 155.270 1.00 30.17  ? 199 CYS A O     1 
ATOM   1349 C CB    . CYS A 1 199 ? 139.874 141.447 154.795 1.00 30.17  ? 199 CYS A CB    1 
ATOM   1350 S SG    . CYS A 1 199 ? 140.431 140.033 153.835 1.00 30.17  ? 199 CYS A SG    1 
ATOM   1351 N N     . ALA A 1 200 ? 142.523 143.358 154.968 1.00 27.73  ? 200 ALA A N     1 
ATOM   1352 C CA    . ALA A 1 200 ? 143.840 143.685 154.446 1.00 27.73  ? 200 ALA A CA    1 
ATOM   1353 C C     . ALA A 1 200 ? 144.840 144.051 155.528 1.00 27.73  ? 200 ALA A C     1 
ATOM   1354 O O     . ALA A 1 200 ? 146.043 144.036 155.257 1.00 27.73  ? 200 ALA A O     1 
ATOM   1355 C CB    . ALA A 1 200 ? 143.745 144.840 153.447 1.00 27.73  ? 200 ALA A CB    1 
ATOM   1356 N N     . ASP A 1 201 ? 144.376 144.398 156.733 1.00 30.40  ? 201 ASP A N     1 
ATOM   1357 C CA    . ASP A 1 201 ? 145.308 144.699 157.818 1.00 30.40  ? 201 ASP A CA    1 
ATOM   1358 C C     . ASP A 1 201 ? 146.183 143.500 158.160 1.00 30.40  ? 201 ASP A C     1 
ATOM   1359 O O     . ASP A 1 201 ? 147.362 143.663 158.493 1.00 30.40  ? 201 ASP A O     1 
ATOM   1360 C CB    . ASP A 1 201 ? 144.551 145.185 159.054 1.00 30.40  ? 201 ASP A CB    1 
ATOM   1361 C CG    . ASP A 1 201 ? 144.085 146.614 158.920 1.00 30.40  ? 201 ASP A CG    1 
ATOM   1362 O OD1   . ASP A 1 201 ? 144.916 147.462 158.537 1.00 30.40  ? 201 ASP A OD1   1 
ATOM   1363 O OD2   . ASP A 1 201 ? 142.903 146.897 159.198 1.00 30.40  ? 201 ASP A OD2   1 
ATOM   1364 N N     . ILE A 1 202 ? 145.632 142.288 158.068 1.00 39.08  ? 202 ILE A N     1 
ATOM   1365 C CA    . ILE A 1 202 ? 146.400 141.087 158.386 1.00 39.08  ? 202 ILE A CA    1 
ATOM   1366 C C     . ILE A 1 202 ? 147.602 140.975 157.458 1.00 39.08  ? 202 ILE A C     1 
ATOM   1367 O O     . ILE A 1 202 ? 148.747 140.826 157.901 1.00 39.08  ? 202 ILE A O     1 
ATOM   1368 C CB    . ILE A 1 202 ? 145.507 139.841 158.280 1.00 39.08  ? 202 ILE A CB    1 
ATOM   1369 C CG1   . ILE A 1 202 ? 144.341 139.943 159.245 1.00 39.08  ? 202 ILE A CG1   1 
ATOM   1370 C CG2   . ILE A 1 202 ? 146.306 138.590 158.592 1.00 39.08  ? 202 ILE A CG2   1 
ATOM   1371 C CD1   . ILE A 1 202 ? 143.430 138.760 159.190 1.00 39.08  ? 202 ILE A CD1   1 
ATOM   1372 N N     . PHE A 1 203 ? 147.355 141.064 156.150 1.00 63.87  ? 203 PHE A N     1 
ATOM   1373 C CA    . PHE A 1 203 ? 148.434 140.903 155.185 1.00 63.87  ? 203 PHE A CA    1 
ATOM   1374 C C     . PHE A 1 203 ? 149.347 142.118 155.169 1.00 63.87  ? 203 PHE A C     1 
ATOM   1375 O O     . PHE A 1 203 ? 150.543 141.993 154.881 1.00 63.87  ? 203 PHE A O     1 
ATOM   1376 C CB    . PHE A 1 203 ? 147.859 140.643 153.798 1.00 63.87  ? 203 PHE A CB    1 
ATOM   1377 C CG    . PHE A 1 203 ? 146.939 139.461 153.740 1.00 63.87  ? 203 PHE A CG    1 
ATOM   1378 C CD1   . PHE A 1 203 ? 145.600 139.602 154.044 1.00 63.87  ? 203 PHE A CD1   1 
ATOM   1379 C CD2   . PHE A 1 203 ? 147.411 138.212 153.387 1.00 63.87  ? 203 PHE A CD2   1 
ATOM   1380 C CE1   . PHE A 1 203 ? 144.746 138.526 153.998 1.00 63.87  ? 203 PHE A CE1   1 
ATOM   1381 C CE2   . PHE A 1 203 ? 146.560 137.131 153.338 1.00 63.87  ? 203 PHE A CE2   1 
ATOM   1382 C CZ    . PHE A 1 203 ? 145.226 137.289 153.645 1.00 63.87  ? 203 PHE A CZ    1 
ATOM   1383 N N     . PHE A 1 204 ? 148.804 143.298 155.468 1.00 34.79  ? 204 PHE A N     1 
ATOM   1384 C CA    . PHE A 1 204 ? 149.632 144.494 155.561 1.00 34.79  ? 204 PHE A CA    1 
ATOM   1385 C C     . PHE A 1 204 ? 150.617 144.384 156.718 1.00 34.79  ? 204 PHE A C     1 
ATOM   1386 O O     . PHE A 1 204 ? 151.777 144.792 156.599 1.00 34.79  ? 204 PHE A O     1 
ATOM   1387 C CB    . PHE A 1 204 ? 148.735 145.723 155.718 1.00 34.79  ? 204 PHE A CB    1 
ATOM   1388 C CG    . PHE A 1 204 ? 149.478 146.999 155.928 1.00 34.79  ? 204 PHE A CG    1 
ATOM   1389 C CD1   . PHE A 1 204 ? 150.581 147.308 155.158 1.00 34.79  ? 204 PHE A CD1   1 
ATOM   1390 C CD2   . PHE A 1 204 ? 149.066 147.897 156.895 1.00 34.79  ? 204 PHE A CD2   1 
ATOM   1391 C CE1   . PHE A 1 204 ? 151.264 148.489 155.350 1.00 34.79  ? 204 PHE A CE1   1 
ATOM   1392 C CE2   . PHE A 1 204 ? 149.745 149.080 157.091 1.00 34.79  ? 204 PHE A CE2   1 
ATOM   1393 C CZ    . PHE A 1 204 ? 150.845 149.376 156.321 1.00 34.79  ? 204 PHE A CZ    1 
ATOM   1394 N N     . LEU A 1 205 ? 150.175 143.821 157.843 1.00 35.46  ? 205 LEU A N     1 
ATOM   1395 C CA    . LEU A 1 205 ? 151.063 143.543 158.961 1.00 35.46  ? 205 LEU A CA    1 
ATOM   1396 C C     . LEU A 1 205 ? 151.915 142.305 158.738 1.00 35.46  ? 205 LEU A C     1 
ATOM   1397 O O     . LEU A 1 205 ? 152.911 142.124 159.446 1.00 35.46  ? 205 LEU A O     1 
ATOM   1398 C CB    . LEU A 1 205 ? 150.253 143.366 160.246 1.00 35.46  ? 205 LEU A CB    1 
ATOM   1399 C CG    . LEU A 1 205 ? 149.625 144.625 160.840 1.00 35.46  ? 205 LEU A CG    1 
ATOM   1400 C CD1   . LEU A 1 205 ? 148.648 144.260 161.943 1.00 35.46  ? 205 LEU A CD1   1 
ATOM   1401 C CD2   . LEU A 1 205 ? 150.706 145.543 161.362 1.00 35.46  ? 205 LEU A CD2   1 
ATOM   1402 N N     . LYS A 1 206 ? 151.553 141.463 157.774 1.00 39.51  ? 206 LYS A N     1 
ATOM   1403 C CA    . LYS A 1 206 ? 152.222 140.191 157.528 1.00 39.51  ? 206 LYS A CA    1 
ATOM   1404 C C     . LYS A 1 206 ? 152.271 139.361 158.812 1.00 39.51  ? 206 LYS A C     1 
ATOM   1405 O O     . LYS A 1 206 ? 153.306 138.828 159.215 1.00 39.51  ? 206 LYS A O     1 
ATOM   1406 C CB    . LYS A 1 206 ? 153.614 140.421 156.929 1.00 39.51  ? 206 LYS A CB    1 
ATOM   1407 C CG    . LYS A 1 206 ? 153.571 141.054 155.536 1.00 39.51  ? 206 LYS A CG    1 
ATOM   1408 C CD    . LYS A 1 206 ? 154.959 141.288 154.956 1.00 39.51  ? 206 LYS A CD    1 
ATOM   1409 C CE    . LYS A 1 206 ? 154.885 141.812 153.525 1.00 39.51  ? 206 LYS A CE    1 
ATOM   1410 N NZ    . LYS A 1 206 ? 154.319 143.187 153.436 1.00 39.51  ? 206 LYS A NZ    1 
ATOM   1411 N N     . ALA A 1 207 ? 151.106 139.264 159.448 1.00 33.03  ? 207 ALA A N     1 
ATOM   1412 C CA    . ALA A 1 207 ? 150.929 138.518 160.685 1.00 33.03  ? 207 ALA A CA    1 
ATOM   1413 C C     . ALA A 1 207 ? 150.516 137.084 160.384 1.00 33.03  ? 207 ALA A C     1 
ATOM   1414 O O     . ALA A 1 207 ? 149.732 136.831 159.465 1.00 33.03  ? 207 ALA A O     1 
ATOM   1415 C CB    . ALA A 1 207 ? 149.875 139.178 161.572 1.00 33.03  ? 207 ALA A CB    1 
ATOM   1416 N N     . ASP A 1 208 ? 151.030 136.151 161.183 1.00 37.38  ? 208 ASP A N     1 
ATOM   1417 C CA    . ASP A 1 208 ? 150.825 134.724 160.967 1.00 37.38  ? 208 ASP A CA    1 
ATOM   1418 C C     . ASP A 1 208 ? 149.669 134.149 161.774 1.00 37.38  ? 208 ASP A C     1 
ATOM   1419 O O     . ASP A 1 208 ? 148.956 133.270 161.280 1.00 37.38  ? 208 ASP A O     1 
ATOM   1420 C CB    . ASP A 1 208 ? 152.108 133.963 161.301 1.00 37.38  ? 208 ASP A CB    1 
ATOM   1421 C CG    . ASP A 1 208 ? 153.219 134.238 160.312 1.00 37.38  ? 208 ASP A CG    1 
ATOM   1422 O OD1   . ASP A 1 208 ? 152.910 134.520 159.136 1.00 37.38  ? 208 ASP A OD1   1 
ATOM   1423 O OD2   . ASP A 1 208 ? 154.401 134.196 160.712 1.00 37.38  ? 208 ASP A OD2   1 
ATOM   1424 N N     . ILE A 1 209 ? 149.469 134.613 163.004 1.00 37.86  ? 209 ILE A N     1 
ATOM   1425 C CA    . ILE A 1 209 ? 148.359 134.178 163.842 1.00 37.86  ? 209 ILE A CA    1 
ATOM   1426 C C     . ILE A 1 209 ? 147.509 135.394 164.183 1.00 37.86  ? 209 ILE A C     1 
ATOM   1427 O O     . ILE A 1 209 ? 148.040 136.477 164.457 1.00 37.86  ? 209 ILE A O     1 
ATOM   1428 C CB    . ILE A 1 209 ? 148.843 133.450 165.111 1.00 37.86  ? 209 ILE A CB    1 
ATOM   1429 C CG1   . ILE A 1 209 ? 149.688 134.372 165.985 1.00 37.86  ? 209 ILE A CG1   1 
ATOM   1430 C CG2   . ILE A 1 209 ? 149.616 132.190 164.745 1.00 37.86  ? 209 ILE A CG2   1 
ATOM   1431 C CD1   . ILE A 1 209 ? 150.000 133.799 167.344 1.00 37.86  ? 209 ILE A CD1   1 
ATOM   1432 N N     . CYS A 1 210 ? 146.192 135.220 164.132 1.00 40.99  ? 210 CYS A N     1 
ATOM   1433 C CA    . CYS A 1 210 ? 145.233 136.310 164.255 1.00 40.99  ? 210 CYS A CA    1 
ATOM   1434 C C     . CYS A 1 210 ? 144.441 136.120 165.540 1.00 40.99  ? 210 CYS A C     1 
ATOM   1435 O O     . CYS A 1 210 ? 143.810 135.075 165.729 1.00 40.99  ? 210 CYS A O     1 
ATOM   1436 C CB    . CYS A 1 210 ? 144.285 136.319 163.057 1.00 40.99  ? 210 CYS A CB    1 
ATOM   1437 S SG    . CYS A 1 210 ? 145.075 136.586 161.462 1.00 40.99  ? 210 CYS A SG    1 
ATOM   1438 N N     . GLN A 1 211 ? 144.461 137.121 166.418 1.00 45.63  ? 211 GLN A N     1 
ATOM   1439 C CA    . GLN A 1 211 ? 143.631 137.104 167.617 1.00 45.63  ? 211 GLN A CA    1 
ATOM   1440 C C     . GLN A 1 211 ? 142.800 138.380 167.659 1.00 45.63  ? 211 GLN A C     1 
ATOM   1441 O O     . GLN A 1 211 ? 143.341 139.487 167.559 1.00 45.63  ? 211 GLN A O     1 
ATOM   1442 C CB    . GLN A 1 211 ? 144.474 136.927 168.889 1.00 45.63  ? 211 GLN A CB    1 
ATOM   1443 C CG    . GLN A 1 211 ? 145.222 138.153 169.384 1.00 45.63  ? 211 GLN A CG    1 
ATOM   1444 C CD    . GLN A 1 211 ? 145.960 137.909 170.684 1.00 45.63  ? 211 GLN A CD    1 
ATOM   1445 O OE1   . GLN A 1 211 ? 145.352 137.827 171.750 1.00 45.63  ? 211 GLN A OE1   1 
ATOM   1446 N NE2   . GLN A 1 211 ? 147.280 137.812 170.604 1.00 45.63  ? 211 GLN A NE2   1 
ATOM   1447 N N     . LEU A 1 212 ? 141.484 138.216 167.759 1.00 48.91  ? 212 LEU A N     1 
ATOM   1448 C CA    . LEU A 1 212 ? 140.544 139.325 167.870 1.00 48.91  ? 212 LEU A CA    1 
ATOM   1449 C C     . LEU A 1 212 ? 139.349 138.846 168.683 1.00 48.91  ? 212 LEU A C     1 
ATOM   1450 O O     . LEU A 1 212 ? 139.403 137.805 169.345 1.00 48.91  ? 212 LEU A O     1 
ATOM   1451 C CB    . LEU A 1 212 ? 140.108 139.837 166.490 1.00 48.91  ? 212 LEU A CB    1 
ATOM   1452 C CG    . LEU A 1 212 ? 141.166 140.259 165.473 1.00 48.91  ? 212 LEU A CG    1 
ATOM   1453 C CD1   . LEU A 1 212 ? 141.468 139.107 164.541 1.00 48.91  ? 212 LEU A CD1   1 
ATOM   1454 C CD2   . LEU A 1 212 ? 140.716 141.479 164.698 1.00 48.91  ? 212 LEU A CD2   1 
ATOM   1455 N N     . GLY A 1 213 ? 138.265 139.610 168.635 1.00 63.80  ? 213 GLY A N     1 
ATOM   1456 C CA    . GLY A 1 213 ? 137.028 139.180 169.247 1.00 63.80  ? 213 GLY A CA    1 
ATOM   1457 C C     . GLY A 1 213 ? 136.343 138.095 168.439 1.00 63.80  ? 213 GLY A C     1 
ATOM   1458 O O     . GLY A 1 213 ? 136.688 137.806 167.292 1.00 63.80  ? 213 GLY A O     1 
ATOM   1459 N N     . MET A 1 214 ? 135.342 137.473 169.065 1.00 74.62  ? 214 MET A N     1 
ATOM   1460 C CA    . MET A 1 214 ? 134.584 136.424 168.396 1.00 74.62  ? 214 MET A CA    1 
ATOM   1461 C C     . MET A 1 214 ? 133.734 136.968 167.254 1.00 74.62  ? 214 MET A C     1 
ATOM   1462 O O     . MET A 1 214 ? 133.401 136.216 166.332 1.00 74.62  ? 214 MET A O     1 
ATOM   1463 C CB    . MET A 1 214 ? 133.703 135.694 169.414 1.00 74.62  ? 214 MET A CB    1 
ATOM   1464 C CG    . MET A 1 214 ? 132.975 134.471 168.877 1.00 74.62  ? 214 MET A CG    1 
ATOM   1465 S SD    . MET A 1 214 ? 134.102 133.144 168.413 1.00 74.62  ? 214 MET A SD    1 
ATOM   1466 C CE    . MET A 1 214 ? 133.098 132.251 167.230 1.00 74.62  ? 214 MET A CE    1 
ATOM   1467 N N     . ASP A 1 215 ? 133.389 138.256 167.289 1.00 73.83  ? 215 ASP A N     1 
ATOM   1468 C CA    . ASP A 1 215 ? 132.584 138.847 166.227 1.00 73.83  ? 215 ASP A CA    1 
ATOM   1469 C C     . ASP A 1 215 ? 133.342 138.941 164.908 1.00 73.83  ? 215 ASP A C     1 
ATOM   1470 O O     . ASP A 1 215 ? 132.755 138.715 163.844 1.00 73.83  ? 215 ASP A O     1 
ATOM   1471 C CB    . ASP A 1 215 ? 132.093 140.232 166.653 1.00 73.83  ? 215 ASP A CB    1 
ATOM   1472 C CG    . ASP A 1 215 ? 133.201 141.096 167.225 1.00 73.83  ? 215 ASP A CG    1 
ATOM   1473 O OD1   . ASP A 1 215 ? 134.388 140.775 167.007 1.00 73.83  ? 215 ASP A OD1   1 
ATOM   1474 O OD2   . ASP A 1 215 ? 132.883 142.098 167.898 1.00 73.83  ? 215 ASP A OD2   1 
ATOM   1475 N N     . GLN A 1 216 ? 134.635 139.257 164.953 1.00 58.99  ? 216 GLN A N     1 
ATOM   1476 C CA    . GLN A 1 216 ? 135.446 139.423 163.753 1.00 58.99  ? 216 GLN A CA    1 
ATOM   1477 C C     . GLN A 1 216 ? 135.837 138.096 163.113 1.00 58.99  ? 216 GLN A C     1 
ATOM   1478 O O     . GLN A 1 216 ? 136.715 138.075 162.240 1.00 58.99  ? 216 GLN A O     1 
ATOM   1479 C CB    . GLN A 1 216 ? 136.700 140.234 164.084 1.00 58.99  ? 216 GLN A CB    1 
ATOM   1480 C CG    . GLN A 1 216 ? 136.409 141.676 164.457 1.00 58.99  ? 216 GLN A CG    1 
ATOM   1481 C CD    . GLN A 1 216 ? 137.495 142.628 164.005 1.00 58.99  ? 216 GLN A CD    1 
ATOM   1482 O OE1   . GLN A 1 216 ? 138.112 143.316 164.818 1.00 58.99  ? 216 GLN A OE1   1 
ATOM   1483 N NE2   . GLN A 1 216 ? 137.740 142.669 162.702 1.00 58.99  ? 216 GLN A NE2   1 
ATOM   1484 N N     . ARG A 1 217 ? 135.204 136.997 163.530 1.00 58.93  ? 217 ARG A N     1 
ATOM   1485 C CA    . ARG A 1 217 ? 135.510 135.697 162.946 1.00 58.93  ? 217 ARG A CA    1 
ATOM   1486 C C     . ARG A 1 217 ? 135.216 135.681 161.453 1.00 58.93  ? 217 ARG A C     1 
ATOM   1487 O O     . ARG A 1 217 ? 135.950 135.061 160.678 1.00 58.93  ? 217 ARG A O     1 
ATOM   1488 C CB    . ARG A 1 217 ? 134.716 134.602 163.655 1.00 58.93  ? 217 ARG A CB    1 
ATOM   1489 C CG    . ARG A 1 217 ? 135.078 133.199 163.212 1.00 58.93  ? 217 ARG A CG    1 
ATOM   1490 C CD    . ARG A 1 217 ? 134.046 132.199 163.689 1.00 58.93  ? 217 ARG A CD    1 
ATOM   1491 N NE    . ARG A 1 217 ? 132.732 132.479 163.122 1.00 58.93  ? 217 ARG A NE    1 
ATOM   1492 C CZ    . ARG A 1 217 ? 132.354 132.131 161.900 1.00 58.93  ? 217 ARG A CZ    1 
ATOM   1493 N NH1   . ARG A 1 217 ? 133.166 131.479 161.083 1.00 58.93  ? 217 ARG A NH1   1 
ATOM   1494 N NH2   . ARG A 1 217 ? 131.129 132.445 161.486 1.00 58.93  ? 217 ARG A NH2   1 
ATOM   1495 N N     . LYS A 1 218 ? 134.140 136.347 161.029 1.00 57.43  ? 218 LYS A N     1 
ATOM   1496 C CA    . LYS A 1 218 ? 133.821 136.391 159.606 1.00 57.43  ? 218 LYS A CA    1 
ATOM   1497 C C     . LYS A 1 218 ? 134.888 137.144 158.821 1.00 57.43  ? 218 LYS A C     1 
ATOM   1498 O O     . LYS A 1 218 ? 135.259 136.730 157.718 1.00 57.43  ? 218 LYS A O     1 
ATOM   1499 C CB    . LYS A 1 218 ? 132.447 137.020 159.392 1.00 57.43  ? 218 LYS A CB    1 
ATOM   1500 C CG    . LYS A 1 218 ? 131.329 136.304 160.120 1.00 57.43  ? 218 LYS A CG    1 
ATOM   1501 C CD    . LYS A 1 218 ? 130.035 137.076 160.004 1.00 57.43  ? 218 LYS A CD    1 
ATOM   1502 C CE    . LYS A 1 218 ? 130.097 138.334 160.844 1.00 57.43  ? 218 LYS A CE    1 
ATOM   1503 N NZ    . LYS A 1 218 ? 130.558 138.042 162.228 1.00 57.43  ? 218 LYS A NZ    1 
ATOM   1504 N N     . VAL A 1 219 ? 135.400 138.245 159.375 1.00 47.18  ? 219 VAL A N     1 
ATOM   1505 C CA    . VAL A 1 219 ? 136.475 138.979 158.710 1.00 47.18  ? 219 VAL A CA    1 
ATOM   1506 C C     . VAL A 1 219 ? 137.734 138.126 158.630 1.00 47.18  ? 219 VAL A C     1 
ATOM   1507 O O     . VAL A 1 219 ? 138.447 138.132 157.619 1.00 47.18  ? 219 VAL A O     1 
ATOM   1508 C CB    . VAL A 1 219 ? 136.741 140.311 159.434 1.00 47.18  ? 219 VAL A CB    1 
ATOM   1509 C CG1   . VAL A 1 219 ? 137.927 141.019 158.812 1.00 47.18  ? 219 VAL A CG1   1 
ATOM   1510 C CG2   . VAL A 1 219 ? 135.508 141.192 159.385 1.00 47.18  ? 219 VAL A CG2   1 
ATOM   1511 N N     . ASN A 1 220 ? 138.034 137.385 159.696 1.00 49.59  ? 220 ASN A N     1 
ATOM   1512 C CA    . ASN A 1 220 ? 139.208 136.519 159.677 1.00 49.59  ? 220 ASN A CA    1 
ATOM   1513 C C     . ASN A 1 220 ? 139.056 135.395 158.655 1.00 49.59  ? 220 ASN A C     1 
ATOM   1514 O O     . ASN A 1 220 ? 140.019 135.039 157.963 1.00 49.59  ? 220 ASN A O     1 
ATOM   1515 C CB    . ASN A 1 220 ? 139.454 135.967 161.076 1.00 49.59  ? 220 ASN A CB    1 
ATOM   1516 C CG    . ASN A 1 220 ? 139.656 137.065 162.096 1.00 49.59  ? 220 ASN A CG    1 
ATOM   1517 O OD1   . ASN A 1 220 ? 140.338 138.053 161.824 1.00 49.59  ? 220 ASN A OD1   1 
ATOM   1518 N ND2   . ASN A 1 220 ? 139.063 136.904 163.273 1.00 49.59  ? 220 ASN A ND2   1 
ATOM   1519 N N     . VAL A 1 221 ? 137.855 134.827 158.547 1.00 51.41  ? 221 VAL A N     1 
ATOM   1520 C CA    . VAL A 1 221 ? 137.587 133.820 157.524 1.00 51.41  ? 221 VAL A CA    1 
ATOM   1521 C C     . VAL A 1 221 ? 137.726 134.427 156.133 1.00 51.41  ? 221 VAL A C     1 
ATOM   1522 O O     . VAL A 1 221 ? 138.216 133.780 155.198 1.00 51.41  ? 221 VAL A O     1 
ATOM   1523 C CB    . VAL A 1 221 ? 136.194 133.205 157.746 1.00 51.41  ? 221 VAL A CB    1 
ATOM   1524 C CG1   . VAL A 1 221 ? 135.791 132.357 156.565 1.00 51.41  ? 221 VAL A CG1   1 
ATOM   1525 C CG2   . VAL A 1 221 ? 136.187 132.373 159.017 1.00 51.41  ? 221 VAL A CG2   1 
ATOM   1526 N N     . LEU A 1 222 ? 137.297 135.680 155.976 1.00 42.50  ? 222 LEU A N     1 
ATOM   1527 C CA    . LEU A 1 222 ? 137.479 136.382 154.710 1.00 42.50  ? 222 LEU A CA    1 
ATOM   1528 C C     . LEU A 1 222 ? 138.956 136.515 154.368 1.00 42.50  ? 222 LEU A C     1 
ATOM   1529 O O     . LEU A 1 222 ? 139.358 136.323 153.214 1.00 42.50  ? 222 LEU A O     1 
ATOM   1530 C CB    . LEU A 1 222 ? 136.827 137.761 154.791 1.00 42.50  ? 222 LEU A CB    1 
ATOM   1531 C CG    . LEU A 1 222 ? 136.873 138.631 153.542 1.00 42.50  ? 222 LEU A CG    1 
ATOM   1532 C CD1   . LEU A 1 222 ? 135.998 138.006 152.484 1.00 42.50  ? 222 LEU A CD1   1 
ATOM   1533 C CD2   . LEU A 1 222 ? 136.420 140.041 153.857 1.00 42.50  ? 222 LEU A CD2   1 
ATOM   1534 N N     . ALA A 1 223 ? 139.777 136.853 155.362 1.00 40.88  ? 223 ALA A N     1 
ATOM   1535 C CA    . ALA A 1 223 ? 141.216 136.948 155.138 1.00 40.88  ? 223 ALA A CA    1 
ATOM   1536 C C     . ALA A 1 223 ? 141.808 135.600 154.749 1.00 40.88  ? 223 ALA A C     1 
ATOM   1537 O O     . ALA A 1 223 ? 142.661 135.524 153.857 1.00 40.88  ? 223 ALA A O     1 
ATOM   1538 C CB    . ALA A 1 223 ? 141.906 137.494 156.383 1.00 40.88  ? 223 ALA A CB    1 
ATOM   1539 N N     . ARG A 1 224 ? 141.374 134.528 155.414 1.00 50.06  ? 224 ARG A N     1 
ATOM   1540 C CA    . ARG A 1 224 ? 141.841 133.192 155.049 1.00 50.06  ? 224 ARG A CA    1 
ATOM   1541 C C     . ARG A 1 224 ? 141.481 132.856 153.606 1.00 50.06  ? 224 ARG A C     1 
ATOM   1542 O O     . ARG A 1 224 ? 142.314 132.334 152.851 1.00 50.06  ? 224 ARG A O     1 
ATOM   1543 C CB    . ARG A 1 224 ? 141.250 132.149 155.997 1.00 50.06  ? 224 ARG A CB    1 
ATOM   1544 C CG    . ARG A 1 224 ? 141.992 131.983 157.308 1.00 50.06  ? 224 ARG A CG    1 
ATOM   1545 C CD    . ARG A 1 224 ? 141.489 130.757 158.048 1.00 50.06  ? 224 ARG A CD    1 
ATOM   1546 N NE    . ARG A 1 224 ? 142.365 130.377 159.149 1.00 50.06  ? 224 ARG A NE    1 
ATOM   1547 C CZ    . ARG A 1 224 ? 143.285 129.426 159.080 1.00 50.06  ? 224 ARG A CZ    1 
ATOM   1548 N NH1   . ARG A 1 224 ? 143.477 128.729 157.973 1.00 50.06  ? 224 ARG A NH1   1 
ATOM   1549 N NH2   . ARG A 1 224 ? 144.030 129.166 160.150 1.00 50.06  ? 224 ARG A NH2   1 
ATOM   1550 N N     . GLU A 1 225 ? 140.242 133.147 153.206 1.00 50.52  ? 225 GLU A N     1 
ATOM   1551 C CA    . GLU A 1 225 ? 139.823 132.877 151.836 1.00 50.52  ? 225 GLU A CA    1 
ATOM   1552 C C     . GLU A 1 225 ? 140.622 133.697 150.831 1.00 50.52  ? 225 GLU A C     1 
ATOM   1553 O O     . GLU A 1 225 ? 141.005 133.178 149.777 1.00 50.52  ? 225 GLU A O     1 
ATOM   1554 C CB    . GLU A 1 225 ? 138.327 133.147 151.679 1.00 50.52  ? 225 GLU A CB    1 
ATOM   1555 C CG    . GLU A 1 225 ? 137.443 131.974 152.075 1.00 50.52  ? 225 GLU A CG    1 
ATOM   1556 C CD    . GLU A 1 225 ? 135.967 132.267 151.895 1.00 50.52  ? 225 GLU A CD    1 
ATOM   1557 O OE1   . GLU A 1 225 ? 135.504 132.306 150.735 1.00 50.52  ? 225 GLU A OE1   1 
ATOM   1558 O OE2   . GLU A 1 225 ? 135.267 132.451 152.912 1.00 50.52  ? 225 GLU A OE2   1 
ATOM   1559 N N     . TYR A 1 226 ? 140.886 134.969 151.135 1.00 42.21  ? 226 TYR A N     1 
ATOM   1560 C CA    . TYR A 1 226 ? 141.693 135.785 150.233 1.00 42.21  ? 226 TYR A CA    1 
ATOM   1561 C C     . TYR A 1 226 ? 143.110 135.240 150.111 1.00 42.21  ? 226 TYR A C     1 
ATOM   1562 O O     . TYR A 1 226 ? 143.685 135.222 149.015 1.00 42.21  ? 226 TYR A O     1 
ATOM   1563 C CB    . TYR A 1 226 ? 141.735 137.231 150.715 1.00 42.21  ? 226 TYR A CB    1 
ATOM   1564 C CG    . TYR A 1 226 ? 142.765 138.052 149.983 1.00 42.21  ? 226 TYR A CG    1 
ATOM   1565 C CD1   . TYR A 1 226 ? 142.623 138.325 148.632 1.00 42.21  ? 226 TYR A CD1   1 
ATOM   1566 C CD2   . TYR A 1 226 ? 143.898 138.520 150.631 1.00 42.21  ? 226 TYR A CD2   1 
ATOM   1567 C CE1   . TYR A 1 226 ? 143.561 139.070 147.954 1.00 42.21  ? 226 TYR A CE1   1 
ATOM   1568 C CE2   . TYR A 1 226 ? 144.848 139.262 149.959 1.00 42.21  ? 226 TYR A CE2   1 
ATOM   1569 C CZ    . TYR A 1 226 ? 144.675 139.532 148.620 1.00 42.21  ? 226 TYR A CZ    1 
ATOM   1570 O OH    . TYR A 1 226 ? 145.616 140.270 147.941 1.00 42.21  ? 226 TYR A OH    1 
ATOM   1571 N N     . CYS A 1 227 ? 143.595 134.598 151.181 1.00 46.45  ? 227 CYS A N     1 
ATOM   1572 C CA    . CYS A 1 227 ? 144.977 134.039 151.179 1.00 46.45  ? 227 CYS A CA    1 
ATOM   1573 C C     . CYS A 1 227 ? 145.050 132.753 150.355 1.00 46.45  ? 227 CYS A C     1 
ATOM   1574 O O     . CYS A 1 227 ? 146.156 132.404 149.928 1.00 46.45  ? 227 CYS A O     1 
ATOM   1575 C CB    . CYS A 1 227 ? 145.456 133.739 152.589 1.00 46.45  ? 227 CYS A CB    1 
ATOM   1576 S SG    . CYS A 1 227 ? 147.245 133.501 152.705 1.00 46.45  ? 227 CYS A SG    1 
ATOM   1577 N N     . ASP A 1 228 ? 143.933 132.055 150.166 1.00 56.22  ? 228 ASP A N     1 
ATOM   1578 C CA    . ASP A 1 228 ? 143.943 130.854 149.289 1.00 56.22  ? 228 ASP A CA    1 
ATOM   1579 C C     . ASP A 1 228 ? 143.474 131.238 147.892 1.00 56.22  ? 228 ASP A C     1 
ATOM   1580 O O     . ASP A 1 228 ? 143.446 130.350 147.026 1.00 56.22  ? 228 ASP A O     1 
ATOM   1581 C CB    . ASP A 1 228 ? 143.116 129.707 149.858 1.00 56.22  ? 228 ASP A CB    1 
ATOM   1582 C CG    . ASP A 1 228 ? 143.989 128.632 150.477 1.00 56.22  ? 228 ASP A CG    1 
ATOM   1583 O OD1   . ASP A 1 228 ? 145.219 128.710 150.300 1.00 56.22  ? 228 ASP A OD1   1 
ATOM   1584 O OD2   . ASP A 1 228 ? 143.437 127.735 151.134 1.00 56.22  ? 228 ASP A OD2   1 
ATOM   1585 N N     . ASP A 1 229 ? 143.106 132.502 147.693 1.00 51.46  ? 229 ASP A N     1 
ATOM   1586 C CA    . ASP A 1 229 ? 142.724 132.990 146.343 1.00 51.46  ? 229 ASP A CA    1 
ATOM   1587 C C     . ASP A 1 229 ? 143.968 133.664 145.793 1.00 51.46  ? 229 ASP A C     1 
ATOM   1588 O O     . ASP A 1 229 ? 144.004 133.925 144.587 1.00 51.46  ? 229 ASP A O     1 
ATOM   1589 C CB    . ASP A 1 229 ? 141.486 133.885 146.335 1.00 51.46  ? 229 ASP A CB    1 
ATOM   1590 C CG    . ASP A 1 229 ? 140.184 133.111 146.426 1.00 51.46  ? 229 ASP A CG    1 
ATOM   1591 O OD1   . ASP A 1 229 ? 140.248 131.883 146.616 1.00 51.46  ? 229 ASP A OD1   1 
ATOM   1592 O OD2   . ASP A 1 229 ? 139.118 133.743 146.298 1.00 51.46  ? 229 ASP A OD2   1 
ATOM   1593 N N     . ILE A 1 230 ? 144.929 133.971 146.668 1.00 45.57  ? 230 ILE A N     1 
ATOM   1594 C CA    . ILE A 1 230 ? 146.193 134.472 146.135 1.00 45.57  ? 230 ILE A CA    1 
ATOM   1595 C C     . ILE A 1 230 ? 147.324 133.470 146.286 1.00 45.57  ? 230 ILE A C     1 
ATOM   1596 O O     . ILE A 1 230 ? 148.470 133.789 145.941 1.00 45.57  ? 230 ILE A O     1 
ATOM   1597 C CB    . ILE A 1 230 ? 146.604 135.813 146.771 1.00 45.57  ? 230 ILE A CB    1 
ATOM   1598 C CG1   . ILE A 1 230 ? 146.754 135.676 148.286 1.00 45.57  ? 230 ILE A CG1   1 
ATOM   1599 C CG2   . ILE A 1 230 ? 145.614 136.891 146.399 1.00 45.57  ? 230 ILE A CG2   1 
ATOM   1600 C CD1   . ILE A 1 230 ? 147.343 136.900 148.950 1.00 45.57  ? 230 ILE A CD1   1 
ATOM   1601 N N     . LYS A 1 231 ? 147.042 132.276 146.810 1.00 52.49  ? 231 LYS A N     1 
ATOM   1602 C CA    . LYS A 1 231 ? 147.999 131.167 146.806 1.00 52.49  ? 231 LYS A CA    1 
ATOM   1603 C C     . LYS A 1 231 ? 149.237 131.494 147.636 1.00 52.49  ? 231 LYS A C     1 
ATOM   1604 O O     . LYS A 1 231 ? 150.358 131.119 147.287 1.00 52.49  ? 231 LYS A O     1 
ATOM   1605 C CB    . LYS A 1 231 ? 148.399 130.783 145.379 1.00 52.49  ? 231 LYS A CB    1 
ATOM   1606 C CG    . LYS A 1 231 ? 147.239 130.447 144.459 1.00 52.49  ? 231 LYS A CG    1 
ATOM   1607 C CD    . LYS A 1 231 ? 146.720 129.042 144.699 1.00 52.49  ? 231 LYS A CD    1 
ATOM   1608 C CE    . LYS A 1 231 ? 145.532 128.741 143.799 1.00 52.49  ? 231 LYS A CE    1 
ATOM   1609 N NZ    . LYS A 1 231 ? 144.300 129.451 144.239 1.00 52.49  ? 231 LYS A NZ    1 
ATOM   1610 N N     . ARG A 1 232 ? 149.040 132.274 148.694 1.00 49.69  ? 232 ARG A N     1 
ATOM   1611 C CA    . ARG A 1 232 ? 150.162 132.519 149.624 1.00 49.69  ? 232 ARG A CA    1 
ATOM   1612 C C     . ARG A 1 232 ? 150.193 131.314 150.548 1.00 49.69  ? 232 ARG A C     1 
ATOM   1613 O O     . ARG A 1 232 ? 149.114 130.899 150.996 1.00 49.69  ? 232 ARG A O     1 
ATOM   1614 C CB    . ARG A 1 232 ? 149.907 133.798 150.422 1.00 49.69  ? 232 ARG A CB    1 
ATOM   1615 C CG    . ARG A 1 232 ? 150.892 134.082 151.546 1.00 49.69  ? 232 ARG A CG    1 
ATOM   1616 C CD    . ARG A 1 232 ? 150.555 135.413 152.193 1.00 49.69  ? 232 ARG A CD    1 
ATOM   1617 N NE    . ARG A 1 232 ? 151.148 135.622 153.505 1.00 49.69  ? 232 ARG A NE    1 
ATOM   1618 C CZ    . ARG A 1 232 ? 150.542 135.355 154.656 1.00 49.69  ? 232 ARG A CZ    1 
ATOM   1619 N NH1   . ARG A 1 232 ? 149.318 134.860 154.661 1.00 49.69  ? 232 ARG A NH1   1 
ATOM   1620 N NH2   . ARG A 1 232 ? 151.159 135.584 155.799 1.00 49.69  ? 232 ARG A NH2   1 
ATOM   1621 N N     . LYS A 1 233 ? 151.376 130.742 150.759 1.00 60.71  ? 233 LYS A N     1 
ATOM   1622 C CA    . LYS A 1 233 ? 151.508 129.619 151.719 1.00 60.71  ? 233 LYS A CA    1 
ATOM   1623 C C     . LYS A 1 233 ? 151.502 130.213 153.126 1.00 60.71  ? 233 LYS A C     1 
ATOM   1624 O O     . LYS A 1 233 ? 151.781 131.418 153.234 1.00 60.71  ? 233 LYS A O     1 
ATOM   1625 C CB    . LYS A 1 233 ? 152.756 128.793 151.405 1.00 60.71  ? 233 LYS A CB    1 
ATOM   1626 C CG    . LYS A 1 233 ? 152.633 127.926 150.159 1.00 60.71  ? 233 LYS A CG    1 
ATOM   1627 C CD    . LYS A 1 233 ? 151.358 127.109 150.149 1.00 60.71  ? 233 LYS A CD    1 
ATOM   1628 C CE    . LYS A 1 233 ? 151.143 126.339 148.865 1.00 60.71  ? 233 LYS A CE    1 
ATOM   1629 N NZ    . LYS A 1 233 ? 149.849 125.616 148.872 1.00 60.71  ? 233 LYS A NZ    1 
ATOM   1630 N N     . ASN A 1 234 ? 151.164 129.410 154.134 1.00 64.91  ? 234 ASN A N     1 
ATOM   1631 C CA    . ASN A 1 234 ? 151.072 129.914 155.526 1.00 64.91  ? 234 ASN A CA    1 
ATOM   1632 C C     . ASN A 1 234 ? 149.852 130.816 155.620 1.00 64.91  ? 234 ASN A C     1 
ATOM   1633 O O     . ASN A 1 234 ? 150.043 132.042 155.697 1.00 64.91  ? 234 ASN A O     1 
ATOM   1634 C CB    . ASN A 1 234 ? 152.305 130.701 155.979 1.00 64.91  ? 234 ASN A CB    1 
ATOM   1635 C CG    . ASN A 1 234 ? 153.547 129.849 156.132 1.00 64.91  ? 234 ASN A CG    1 
ATOM   1636 O OD1   . ASN A 1 234 ? 153.556 128.679 155.757 1.00 64.91  ? 234 ASN A OD1   1 
ATOM   1637 N ND2   . ASN A 1 234 ? 154.601 130.430 156.682 1.00 64.91  ? 234 ASN A ND2   1 
ATOM   1638 N N     . LYS A 1 235 ? 148.654 130.234 155.606 1.00 49.49  ? 235 LYS A N     1 
ATOM   1639 C CA    . LYS A 1 235 ? 147.458 131.045 155.777 1.00 49.49  ? 235 LYS A CA    1 
ATOM   1640 C C     . LYS A 1 235 ? 147.357 131.523 157.224 1.00 49.49  ? 235 LYS A C     1 
ATOM   1641 O O     . LYS A 1 235 ? 147.712 130.780 158.148 1.00 49.49  ? 235 LYS A O     1 
ATOM   1642 C CB    . LYS A 1 235 ? 146.209 130.245 155.402 1.00 49.49  ? 235 LYS A CB    1 
ATOM   1643 C CG    . LYS A 1 235 ? 146.296 129.562 154.049 1.00 49.49  ? 235 LYS A CG    1 
ATOM   1644 C CD    . LYS A 1 235 ? 145.176 128.554 153.856 1.00 49.49  ? 235 LYS A CD    1 
ATOM   1645 C CE    . LYS A 1 235 ? 143.818 129.168 154.140 1.00 49.49  ? 235 LYS A CE    1 
ATOM   1646 N NZ    . LYS A 1 235 ? 142.710 128.246 153.769 1.00 49.49  ? 235 LYS A NZ    1 
ATOM   1647 N N     . PRO A 1 236 ? 146.898 132.753 157.457 1.00 39.40  ? 236 PRO A N     1 
ATOM   1648 C CA    . PRO A 1 236 ? 146.866 133.280 158.826 1.00 39.40  ? 236 PRO A CA    1 
ATOM   1649 C C     . PRO A 1 236 ? 146.003 132.419 159.735 1.00 39.40  ? 236 PRO A C     1 
ATOM   1650 O O     . PRO A 1 236 ? 144.954 131.912 159.333 1.00 39.40  ? 236 PRO A O     1 
ATOM   1651 C CB    . PRO A 1 236 ? 146.281 134.687 158.654 1.00 39.40  ? 236 PRO A CB    1 
ATOM   1652 C CG    . PRO A 1 236 ? 145.581 134.658 157.339 1.00 39.40  ? 236 PRO A CG    1 
ATOM   1653 C CD    . PRO A 1 236 ? 146.360 133.714 156.481 1.00 39.40  ? 236 PRO A CD    1 
ATOM   1654 N N     . ILE A 1 237 ? 146.459 132.260 160.971 1.00 41.84  ? 237 ILE A N     1 
ATOM   1655 C CA    . ILE A 1 237 ? 145.837 131.350 161.925 1.00 41.84  ? 237 ILE A CA    1 
ATOM   1656 C C     . ILE A 1 237 ? 144.959 132.155 162.870 1.00 41.84  ? 237 ILE A C     1 
ATOM   1657 O O     . ILE A 1 237 ? 145.422 133.113 163.500 1.00 41.84  ? 237 ILE A O     1 
ATOM   1658 C CB    . ILE A 1 237 ? 146.905 130.559 162.694 1.00 41.84  ? 237 ILE A CB    1 
ATOM   1659 C CG1   . ILE A 1 237 ? 147.698 129.691 161.720 1.00 41.84  ? 237 ILE A CG1   1 
ATOM   1660 C CG2   . ILE A 1 237 ? 146.261 129.699 163.764 1.00 41.84  ? 237 ILE A CG2   1 
ATOM   1661 C CD1   . ILE A 1 237 ? 148.928 129.075 162.318 1.00 41.84  ? 237 ILE A CD1   1 
ATOM   1662 N N     . ILE A 1 238 ? 143.694 131.765 162.980 1.00 47.71  ? 238 ILE A N     1 
ATOM   1663 C CA    . ILE A 1 238 ? 142.698 132.531 163.718 1.00 47.71  ? 238 ILE A CA    1 
ATOM   1664 C C     . ILE A 1 238 ? 142.642 132.014 165.146 1.00 47.71  ? 238 ILE A C     1 
ATOM   1665 O O     . ILE A 1 238 ? 142.373 130.829 165.377 1.00 47.71  ? 238 ILE A O     1 
ATOM   1666 C CB    . ILE A 1 238 ? 141.318 132.447 163.045 1.00 47.71  ? 238 ILE A CB    1 
ATOM   1667 C CG1   . ILE A 1 238 ? 141.441 132.732 161.546 1.00 47.71  ? 238 ILE A CG1   1 
ATOM   1668 C CG2   . ILE A 1 238 ? 140.346 133.407 163.704 1.00 47.71  ? 238 ILE A CG2   1 
ATOM   1669 C CD1   . ILE A 1 238 ? 142.262 133.960 161.212 1.00 47.71  ? 238 ILE A CD1   1 
ATOM   1670 N N     . LEU A 1 239 ? 142.896 132.903 166.104 1.00 47.95  ? 239 LEU A N     1 
ATOM   1671 C CA    . LEU A 1 239 ? 142.892 132.577 167.529 1.00 47.95  ? 239 LEU A CA    1 
ATOM   1672 C C     . LEU A 1 239 ? 141.846 133.475 168.182 1.00 47.95  ? 239 LEU A C     1 
ATOM   1673 O O     . LEU A 1 239 ? 142.171 134.542 168.709 1.00 47.95  ? 239 LEU A O     1 
ATOM   1674 C CB    . LEU A 1 239 ? 144.279 132.777 168.128 1.00 47.95  ? 239 LEU A CB    1 
ATOM   1675 C CG    . LEU A 1 239 ? 144.600 132.080 169.447 1.00 47.95  ? 239 LEU A CG    1 
ATOM   1676 C CD1   . LEU A 1 239 ? 144.511 130.580 169.276 1.00 47.95  ? 239 LEU A CD1   1 
ATOM   1677 C CD2   . LEU A 1 239 ? 145.983 132.482 169.923 1.00 47.95  ? 239 LEU A CD2   1 
ATOM   1678 N N     . SER A 1 240 ? 140.591 133.036 168.155 1.00 52.50  ? 240 SER A N     1 
ATOM   1679 C CA    . SER A 1 240 ? 139.483 133.872 168.594 1.00 52.50  ? 240 SER A CA    1 
ATOM   1680 C C     . SER A 1 240 ? 139.427 133.946 170.114 1.00 52.50  ? 240 SER A C     1 
ATOM   1681 O O     . SER A 1 240 ? 139.529 132.925 170.800 1.00 52.50  ? 240 SER A O     1 
ATOM   1682 C CB    . SER A 1 240 ? 138.164 133.335 168.042 1.00 52.50  ? 240 SER A CB    1 
ATOM   1683 O OG    . SER A 1 240 ? 138.224 133.191 166.634 1.00 52.50  ? 240 SER A OG    1 
ATOM   1684 N N     . HIS A 1 241 ? 139.267 135.159 170.635 1.00 53.85  ? 241 HIS A N     1 
ATOM   1685 C CA    . HIS A 1 241 ? 139.071 135.365 172.060 1.00 53.85  ? 241 HIS A CA    1 
ATOM   1686 C C     . HIS A 1 241 ? 137.640 135.009 172.457 1.00 53.85  ? 241 HIS A C     1 
ATOM   1687 O O     . HIS A 1 241 ? 136.776 134.750 171.616 1.00 53.85  ? 241 HIS A O     1 
ATOM   1688 C CB    . HIS A 1 241 ? 139.374 136.812 172.442 1.00 53.85  ? 241 HIS A CB    1 
ATOM   1689 C CG    . HIS A 1 241 ? 140.821 137.081 172.708 1.00 53.85  ? 241 HIS A CG    1 
ATOM   1690 N ND1   . HIS A 1 241 ? 141.325 138.354 172.857 1.00 53.85  ? 241 HIS A ND1   1 
ATOM   1691 C CD2   . HIS A 1 241 ? 141.873 136.241 172.852 1.00 53.85  ? 241 HIS A CD2   1 
ATOM   1692 C CE1   . HIS A 1 241 ? 142.625 138.288 173.082 1.00 53.85  ? 241 HIS A CE1   1 
ATOM   1693 N NE2   . HIS A 1 241 ? 142.982 137.017 173.083 1.00 53.85  ? 241 HIS A NE2   1 
ATOM   1694 N N     . HIS A 1 242 ? 137.395 135.001 173.763 1.00 68.23  ? 242 HIS A N     1 
ATOM   1695 C CA    . HIS A 1 242 ? 136.058 134.811 174.303 1.00 68.23  ? 242 HIS A CA    1 
ATOM   1696 C C     . HIS A 1 242 ? 135.540 136.132 174.856 1.00 68.23  ? 242 HIS A C     1 
ATOM   1697 O O     . HIS A 1 242 ? 136.244 136.828 175.593 1.00 68.23  ? 242 HIS A O     1 
ATOM   1698 C CB    . HIS A 1 242 ? 136.049 133.744 175.399 1.00 68.23  ? 242 HIS A CB    1 
ATOM   1699 C CG    . HIS A 1 242 ? 134.739 133.032 175.535 1.00 68.23  ? 242 HIS A CG    1 
ATOM   1700 N ND1   . HIS A 1 242 ? 134.557 131.962 176.383 1.00 68.23  ? 242 HIS A ND1   1 
ATOM   1701 C CD2   . HIS A 1 242 ? 133.546 133.237 174.927 1.00 68.23  ? 242 HIS A CD2   1 
ATOM   1702 C CE1   . HIS A 1 242 ? 133.309 131.538 176.293 1.00 68.23  ? 242 HIS A CE1   1 
ATOM   1703 N NE2   . HIS A 1 242 ? 132.674 132.295 175.417 1.00 68.23  ? 242 HIS A NE2   1 
ATOM   1704 N N     . MET A 1 243 ? 134.306 136.471 174.496 1.00 78.27  ? 243 MET A N     1 
ATOM   1705 C CA    . MET A 1 243 ? 133.707 137.747 174.858 1.00 78.27  ? 243 MET A CA    1 
ATOM   1706 C C     . MET A 1 243 ? 133.038 137.640 176.222 1.00 78.27  ? 243 MET A C     1 
ATOM   1707 O O     . MET A 1 243 ? 132.198 136.762 176.441 1.00 78.27  ? 243 MET A O     1 
ATOM   1708 C CB    . MET A 1 243 ? 132.689 138.187 173.805 1.00 78.27  ? 243 MET A CB    1 
ATOM   1709 C CG    . MET A 1 243 ? 133.208 138.130 172.379 1.00 78.27  ? 243 MET A CG    1 
ATOM   1710 S SD    . MET A 1 243 ? 134.147 139.600 171.925 1.00 78.27  ? 243 MET A SD    1 
ATOM   1711 C CE    . MET A 1 243 ? 132.855 140.620 171.221 1.00 78.27  ? 243 MET A CE    1 
ATOM   1712 N N     . LEU A 1 244 ? 133.415 138.531 177.128 1.00 86.40  ? 244 LEU A N     1 
ATOM   1713 C CA    . LEU A 1 244 ? 132.807 138.569 178.452 1.00 86.40  ? 244 LEU A CA    1 
ATOM   1714 C C     . LEU A 1 244 ? 131.436 139.234 178.375 1.00 86.40  ? 244 LEU A C     1 
ATOM   1715 O O     . LEU A 1 244 ? 131.299 140.282 177.736 1.00 86.40  ? 244 LEU A O     1 
ATOM   1716 C CB    . LEU A 1 244 ? 133.705 139.316 179.430 1.00 86.40  ? 244 LEU A CB    1 
ATOM   1717 C CG    . LEU A 1 244 ? 135.063 138.661 179.690 1.00 86.40  ? 244 LEU A CG    1 
ATOM   1718 C CD1   . LEU A 1 244 ? 135.902 139.497 180.645 1.00 86.40  ? 244 LEU A CD1   1 
ATOM   1719 C CD2   . LEU A 1 244 ? 134.880 137.251 180.227 1.00 86.40  ? 244 LEU A CD2   1 
ATOM   1720 N N     . PRO A 1 245 ? 130.415 138.668 179.004 1.00 91.20  ? 245 PRO A N     1 
ATOM   1721 C CA    . PRO A 1 245 ? 129.061 139.212 178.895 1.00 91.20  ? 245 PRO A CA    1 
ATOM   1722 C C     . PRO A 1 245 ? 128.812 140.280 179.955 1.00 91.20  ? 245 PRO A C     1 
ATOM   1723 O O     . PRO A 1 245 ? 129.688 140.631 180.744 1.00 91.20  ? 245 PRO A O     1 
ATOM   1724 C CB    . PRO A 1 245 ? 128.178 137.983 179.117 1.00 91.20  ? 245 PRO A CB    1 
ATOM   1725 C CG    . PRO A 1 245 ? 129.029 137.030 179.935 1.00 91.20  ? 245 PRO A CG    1 
ATOM   1726 C CD    . PRO A 1 245 ? 130.465 137.502 179.898 1.00 91.20  ? 245 PRO A CD    1 
ATOM   1727 N N     . GLY A 1 246 ? 127.585 140.798 179.958 1.00 100.39 ? 246 GLY A N     1 
ATOM   1728 C CA    . GLY A 1 246 ? 127.216 141.810 180.924 1.00 100.39 ? 246 GLY A CA    1 
ATOM   1729 C C     . GLY A 1 246 ? 127.008 141.241 182.314 1.00 100.39 ? 246 GLY A C     1 
ATOM   1730 O O     . GLY A 1 246 ? 126.667 140.073 182.501 1.00 100.39 ? 246 GLY A O     1 
ATOM   1731 N N     . LEU A 1 247 ? 127.227 142.101 183.312 1.00 100.75 ? 247 LEU A N     1 
ATOM   1732 C CA    . LEU A 1 247 ? 127.053 141.685 184.701 1.00 100.75 ? 247 LEU A CA    1 
ATOM   1733 C C     . LEU A 1 247 ? 125.599 141.347 185.004 1.00 100.75 ? 247 LEU A C     1 
ATOM   1734 O O     . LEU A 1 247 ? 125.317 140.366 185.701 1.00 100.75 ? 247 LEU A O     1 
ATOM   1735 C CB    . LEU A 1 247 ? 127.555 142.777 185.644 1.00 100.75 ? 247 LEU A CB    1 
ATOM   1736 C CG    . LEU A 1 247 ? 128.991 143.241 185.408 1.00 100.75 ? 247 LEU A CG    1 
ATOM   1737 C CD1   . LEU A 1 247 ? 129.320 144.436 186.282 1.00 100.75 ? 247 LEU A CD1   1 
ATOM   1738 C CD2   . LEU A 1 247 ? 129.950 142.100 185.680 1.00 100.75 ? 247 LEU A CD2   1 
ATOM   1739 N N     . GLN A 1 248 ? 124.665 142.145 184.496 1.00 104.98 ? 248 GLN A N     1 
ATOM   1740 C CA    . GLN A 1 248 ? 123.250 141.893 184.722 1.00 104.98 ? 248 GLN A CA    1 
ATOM   1741 C C     . GLN A 1 248 ? 122.762 140.803 183.778 1.00 104.98 ? 248 GLN A C     1 
ATOM   1742 O O     . GLN A 1 248 ? 123.068 140.822 182.581 1.00 104.98 ? 248 GLN A O     1 
ATOM   1743 C CB    . GLN A 1 248 ? 122.441 143.174 184.523 1.00 104.98 ? 248 GLN A CB    1 
ATOM   1744 C CG    . GLN A 1 248 ? 122.890 144.331 185.403 1.00 104.98 ? 248 GLN A CG    1 
ATOM   1745 C CD    . GLN A 1 248 ? 122.704 144.047 186.881 1.00 104.98 ? 248 GLN A CD    1 
ATOM   1746 O OE1   . GLN A 1 248 ? 121.593 143.781 187.339 1.00 104.98 ? 248 GLN A OE1   1 
ATOM   1747 N NE2   . GLN A 1 248 ? 123.795 144.104 187.636 1.00 104.98 ? 248 GLN A NE2   1 
ATOM   1748 N N     . GLN A 1 249 ? 122.009 139.848 184.321 1.00 112.56 ? 249 GLN A N     1 
ATOM   1749 C CA    . GLN A 1 249 ? 121.506 138.741 183.518 1.00 112.56 ? 249 GLN A CA    1 
ATOM   1750 C C     . GLN A 1 249 ? 120.563 139.250 182.436 1.00 112.56 ? 249 GLN A C     1 
ATOM   1751 O O     . GLN A 1 249 ? 119.752 140.151 182.672 1.00 112.56 ? 249 GLN A O     1 
ATOM   1752 C CB    . GLN A 1 249 ? 120.796 137.722 184.409 1.00 112.56 ? 249 GLN A CB    1 
ATOM   1753 C CG    . GLN A 1 249 ? 120.438 136.423 183.704 1.00 112.56 ? 249 GLN A CG    1 
ATOM   1754 C CD    . GLN A 1 249 ? 121.567 135.893 182.839 1.00 112.56 ? 249 GLN A CD    1 
ATOM   1755 O OE1   . GLN A 1 249 ? 121.391 135.663 181.643 1.00 112.56 ? 249 GLN A OE1   1 
ATOM   1756 N NE2   . GLN A 1 249 ? 122.732 135.690 183.443 1.00 112.56 ? 249 GLN A NE2   1 
ATOM   1757 N N     . GLY A 1 250 ? 120.672 138.666 181.246 1.00 115.92 ? 250 GLY A N     1 
ATOM   1758 C CA    . GLY A 1 250 ? 119.905 139.078 180.086 1.00 115.92 ? 250 GLY A CA    1 
ATOM   1759 C C     . GLY A 1 250 ? 120.723 139.757 179.010 1.00 115.92 ? 250 GLY A C     1 
ATOM   1760 O O     . GLY A 1 250 ? 120.278 139.820 177.855 1.00 115.92 ? 250 GLY A O     1 
ATOM   1761 N N     . GLN A 1 251 ? 121.906 140.268 179.344 1.00 113.86 ? 251 GLN A N     1 
ATOM   1762 C CA    . GLN A 1 251 ? 122.792 140.914 178.384 1.00 113.86 ? 251 GLN A CA    1 
ATOM   1763 C C     . GLN A 1 251 ? 124.056 140.077 178.251 1.00 113.86 ? 251 GLN A C     1 
ATOM   1764 O O     . GLN A 1 251 ? 124.788 139.893 179.229 1.00 113.86 ? 251 GLN A O     1 
ATOM   1765 C CB    . GLN A 1 251 ? 123.133 142.339 178.822 1.00 113.86 ? 251 GLN A CB    1 
ATOM   1766 C CG    . GLN A 1 251 ? 121.922 143.176 179.203 1.00 113.86 ? 251 GLN A CG    1 
ATOM   1767 C CD    . GLN A 1 251 ? 122.241 144.655 179.288 1.00 113.86 ? 251 GLN A CD    1 
ATOM   1768 O OE1   . GLN A 1 251 ? 123.076 145.077 180.087 1.00 113.86 ? 251 GLN A OE1   1 
ATOM   1769 N NE2   . GLN A 1 251 ? 121.572 145.453 178.463 1.00 113.86 ? 251 GLN A NE2   1 
ATOM   1770 N N     . GLU A 1 252 ? 124.307 139.573 177.045 1.00 111.80 ? 252 GLU A N     1 
ATOM   1771 C CA    . GLU A 1 252 ? 125.472 138.746 176.766 1.00 111.80 ? 252 GLU A CA    1 
ATOM   1772 C C     . GLU A 1 252 ? 126.591 139.510 176.073 1.00 111.80 ? 252 GLU A C     1 
ATOM   1773 O O     . GLU A 1 252 ? 127.642 138.924 175.793 1.00 111.80 ? 252 GLU A O     1 
ATOM   1774 C CB    . GLU A 1 252 ? 125.068 137.542 175.909 1.00 111.80 ? 252 GLU A CB    1 
ATOM   1775 C CG    . GLU A 1 252 ? 124.796 137.885 174.452 1.00 111.80 ? 252 GLU A CG    1 
ATOM   1776 C CD    . GLU A 1 252 ? 123.376 138.364 174.214 1.00 111.80 ? 252 GLU A CD    1 
ATOM   1777 O OE1   . GLU A 1 252 ? 122.661 138.635 175.202 1.00 111.80 ? 252 GLU A OE1   1 
ATOM   1778 O OE2   . GLU A 1 252 ? 122.975 138.475 173.037 1.00 111.80 ? 252 GLU A OE2   1 
ATOM   1779 N N     . LYS A 1 253 ? 126.397 140.793 175.794 1.00 105.42 ? 253 LYS A N     1 
ATOM   1780 C CA    . LYS A 1 253 ? 127.362 141.589 175.053 1.00 105.42 ? 253 LYS A CA    1 
ATOM   1781 C C     . LYS A 1 253 ? 128.213 142.430 175.998 1.00 105.42 ? 253 LYS A C     1 
ATOM   1782 O O     . LYS A 1 253 ? 127.940 142.550 177.194 1.00 105.42 ? 253 LYS A O     1 
ATOM   1783 C CB    . LYS A 1 253 ? 126.646 142.488 174.040 1.00 105.42 ? 253 LYS A CB    1 
ATOM   1784 C CG    . LYS A 1 253 ? 125.873 143.633 174.674 1.00 105.42 ? 253 LYS A CG    1 
ATOM   1785 C CD    . LYS A 1 253 ? 125.266 144.546 173.622 1.00 105.42 ? 253 LYS A CD    1 
ATOM   1786 C CE    . LYS A 1 253 ? 124.413 145.631 174.261 1.00 105.42 ? 253 LYS A CE    1 
ATOM   1787 N NZ    . LYS A 1 253 ? 125.221 146.547 175.115 1.00 105.42 ? 253 LYS A NZ    1 
ATOM   1788 N N     . MET A 1 254 ? 129.264 143.017 175.435 1.00 101.67 ? 254 MET A N     1 
ATOM   1789 C CA    . MET A 1 254 ? 130.140 143.935 176.145 1.00 101.67 ? 254 MET A CA    1 
ATOM   1790 C C     . MET A 1 254 ? 130.016 145.322 175.530 1.00 101.67 ? 254 MET A C     1 
ATOM   1791 O O     . MET A 1 254 ? 129.885 145.461 174.309 1.00 101.67 ? 254 MET A O     1 
ATOM   1792 C CB    . MET A 1 254 ? 131.596 143.462 176.095 1.00 101.67 ? 254 MET A CB    1 
ATOM   1793 C CG    . MET A 1 254 ? 132.177 143.376 174.691 1.00 101.67 ? 254 MET A CG    1 
ATOM   1794 S SD    . MET A 1 254 ? 133.916 142.908 174.674 1.00 101.67 ? 254 MET A SD    1 
ATOM   1795 C CE    . MET A 1 254 ? 133.890 141.490 175.764 1.00 101.67 ? 254 MET A CE    1 
ATOM   1796 N N     . SER A 1 255 ? 130.042 146.348 176.378 1.00 98.27  ? 255 SER A N     1 
ATOM   1797 C CA    . SER A 1 255 ? 129.912 147.717 175.898 1.00 98.27  ? 255 SER A CA    1 
ATOM   1798 C C     . SER A 1 255 ? 130.529 148.663 176.914 1.00 98.27  ? 255 SER A C     1 
ATOM   1799 O O     . SER A 1 255 ? 130.143 148.654 178.087 1.00 98.27  ? 255 SER A O     1 
ATOM   1800 C CB    . SER A 1 255 ? 128.442 148.079 175.654 1.00 98.27  ? 255 SER A CB    1 
ATOM   1801 O OG    . SER A 1 255 ? 128.319 149.391 175.133 1.00 98.27  ? 255 SER A OG    1 
ATOM   1802 N N     . LYS A 1 256 ? 131.486 149.474 176.460 1.00 91.15  ? 256 LYS A N     1 
ATOM   1803 C CA    . LYS A 1 256 ? 132.066 150.506 177.309 1.00 91.15  ? 256 LYS A CA    1 
ATOM   1804 C C     . LYS A 1 256 ? 131.143 151.704 177.479 1.00 91.15  ? 256 LYS A C     1 
ATOM   1805 O O     . LYS A 1 256 ? 131.295 152.455 178.449 1.00 91.15  ? 256 LYS A O     1 
ATOM   1806 C CB    . LYS A 1 256 ? 133.409 150.962 176.736 1.00 91.15  ? 256 LYS A CB    1 
ATOM   1807 C CG    . LYS A 1 256 ? 133.328 151.473 175.307 1.00 91.15  ? 256 LYS A CG    1 
ATOM   1808 C CD    . LYS A 1 256 ? 134.669 151.363 174.605 1.00 91.15  ? 256 LYS A CD    1 
ATOM   1809 C CE    . LYS A 1 256 ? 134.974 149.928 174.212 1.00 91.15  ? 256 LYS A CE    1 
ATOM   1810 N NZ    . LYS A 1 256 ? 136.181 149.835 173.345 1.00 91.15  ? 256 LYS A NZ    1 
ATOM   1811 N N     . SER A 1 257 ? 130.195 151.900 176.560 1.00 98.23  ? 257 SER A N     1 
ATOM   1812 C CA    . SER A 1 257 ? 129.228 152.981 176.699 1.00 98.23  ? 257 SER A CA    1 
ATOM   1813 C C     . SER A 1 257 ? 128.184 152.675 177.765 1.00 98.23  ? 257 SER A C     1 
ATOM   1814 O O     . SER A 1 257 ? 127.576 153.600 178.314 1.00 98.23  ? 257 SER A O     1 
ATOM   1815 C CB    . SER A 1 257 ? 128.544 153.253 175.358 1.00 98.23  ? 257 SER A CB    1 
ATOM   1816 O OG    . SER A 1 257 ? 127.895 152.090 174.873 1.00 98.23  ? 257 SER A OG    1 
ATOM   1817 N N     . ASP A 1 258 ? 127.963 151.395 178.066 1.00 98.49  ? 258 ASP A N     1 
ATOM   1818 C CA    . ASP A 1 258 ? 127.017 151.003 179.097 1.00 98.49  ? 258 ASP A CA    1 
ATOM   1819 C C     . ASP A 1 258 ? 127.782 150.623 180.353 1.00 98.49  ? 258 ASP A C     1 
ATOM   1820 O O     . ASP A 1 258 ? 128.413 149.555 180.383 1.00 98.49  ? 258 ASP A O     1 
ATOM   1821 C CB    . ASP A 1 258 ? 126.158 149.832 178.622 1.00 98.49  ? 258 ASP A CB    1 
ATOM   1822 C CG    . ASP A 1 258 ? 125.154 149.388 179.665 1.00 98.49  ? 258 ASP A CG    1 
ATOM   1823 O OD1   . ASP A 1 258 ? 124.233 150.170 179.977 1.00 98.49  ? 258 ASP A OD1   1 
ATOM   1824 O OD2   . ASP A 1 258 ? 125.288 148.256 180.176 1.00 98.49  ? 258 ASP A OD2   1 
ATOM   1825 N N     . PRO A 1 259 ? 127.760 151.443 181.407 1.00 100.02 ? 259 PRO A N     1 
ATOM   1826 C CA    . PRO A 1 259 ? 128.507 151.113 182.626 1.00 100.02 ? 259 PRO A CA    1 
ATOM   1827 C C     . PRO A 1 259 ? 127.855 150.045 183.489 1.00 100.02 ? 259 PRO A C     1 
ATOM   1828 O O     . PRO A 1 259 ? 128.420 149.691 184.529 1.00 100.02 ? 259 PRO A O     1 
ATOM   1829 C CB    . PRO A 1 259 ? 128.555 152.456 183.370 1.00 100.02 ? 259 PRO A CB    1 
ATOM   1830 C CG    . PRO A 1 259 ? 127.345 153.182 182.900 1.00 100.02 ? 259 PRO A CG    1 
ATOM   1831 C CD    . PRO A 1 259 ? 127.156 152.784 181.467 1.00 100.02 ? 259 PRO A CD    1 
ATOM   1832 N N     . SER A 1 260 ? 126.694 149.526 183.099 1.00 102.32 ? 260 SER A N     1 
ATOM   1833 C CA    . SER A 1 260 ? 125.976 148.539 183.892 1.00 102.32 ? 260 SER A CA    1 
ATOM   1834 C C     . SER A 1 260 ? 126.305 147.104 183.499 1.00 102.32 ? 260 SER A C     1 
ATOM   1835 O O     . SER A 1 260 ? 125.691 146.174 184.032 1.00 102.32 ? 260 SER A O     1 
ATOM   1836 C CB    . SER A 1 260 ? 124.466 148.771 183.780 1.00 102.32 ? 260 SER A CB    1 
ATOM   1837 O OG    . SER A 1 260 ? 124.035 148.682 182.434 1.00 102.32 ? 260 SER A OG    1 
ATOM   1838 N N     . SER A 1 261 ? 127.254 146.899 182.584 1.00 99.86  ? 261 SER A N     1 
ATOM   1839 C CA    . SER A 1 261 ? 127.563 145.564 182.092 1.00 99.86  ? 261 SER A CA    1 
ATOM   1840 C C     . SER A 1 261 ? 129.020 145.152 182.247 1.00 99.86  ? 261 SER A C     1 
ATOM   1841 O O     . SER A 1 261 ? 129.315 143.960 182.109 1.00 99.86  ? 261 SER A O     1 
ATOM   1842 C CB    . SER A 1 261 ? 127.176 145.437 180.610 1.00 99.86  ? 261 SER A CB    1 
ATOM   1843 O OG    . SER A 1 261 ? 125.777 145.574 180.434 1.00 99.86  ? 261 SER A OG    1 
ATOM   1844 N N     . SER A 1 262 ? 129.935 146.078 182.528 1.00 91.96  ? 262 SER A N     1 
ATOM   1845 C CA    . SER A 1 262 ? 131.344 145.729 182.622 1.00 91.96  ? 262 SER A CA    1 
ATOM   1846 C C     . SER A 1 262 ? 132.039 146.665 183.598 1.00 91.96  ? 262 SER A C     1 
ATOM   1847 O O     . SER A 1 262 ? 131.563 147.767 183.883 1.00 91.96  ? 262 SER A O     1 
ATOM   1848 C CB    . SER A 1 262 ? 132.029 145.783 181.251 1.00 91.96  ? 262 SER A CB    1 
ATOM   1849 O OG    . SER A 1 262 ? 131.662 144.671 180.454 1.00 91.96  ? 262 SER A OG    1 
ATOM   1850 N N     . VAL A 1 263 ? 133.179 146.207 184.107 1.00 78.90  ? 263 VAL A N     1 
ATOM   1851 C CA    . VAL A 1 263 ? 134.006 146.980 185.024 1.00 78.90  ? 263 VAL A CA    1 
ATOM   1852 C C     . VAL A 1 263 ? 135.243 147.458 184.279 1.00 78.90  ? 263 VAL A C     1 
ATOM   1853 O O     . VAL A 1 263 ? 135.776 146.769 183.401 1.00 78.90  ? 263 VAL A O     1 
ATOM   1854 C CB    . VAL A 1 263 ? 134.379 146.156 186.277 1.00 78.90  ? 263 VAL A CB    1 
ATOM   1855 C CG1   . VAL A 1 263 ? 135.257 144.971 185.906 1.00 78.90  ? 263 VAL A CG1   1 
ATOM   1856 C CG2   . VAL A 1 263 ? 135.063 147.033 187.317 1.00 78.90  ? 263 VAL A CG2   1 
ATOM   1857 N N     . PHE A 1 264 ? 135.692 148.662 184.613 1.00 79.76  ? 264 PHE A N     1 
ATOM   1858 C CA    . PHE A 1 264 ? 136.833 149.287 183.964 1.00 79.76  ? 264 PHE A CA    1 
ATOM   1859 C C     . PHE A 1 264 ? 138.018 149.314 184.922 1.00 79.76  ? 264 PHE A C     1 
ATOM   1860 O O     . PHE A 1 264 ? 137.887 149.052 186.120 1.00 79.76  ? 264 PHE A O     1 
ATOM   1861 C CB    . PHE A 1 264 ? 136.490 150.711 183.508 1.00 79.76  ? 264 PHE A CB    1 
ATOM   1862 C CG    . PHE A 1 264 ? 135.272 150.802 182.621 1.00 79.76  ? 264 PHE A CG    1 
ATOM   1863 C CD1   . PHE A 1 264 ? 134.796 149.698 181.935 1.00 79.76  ? 264 PHE A CD1   1 
ATOM   1864 C CD2   . PHE A 1 264 ? 134.595 152.001 182.491 1.00 79.76  ? 264 PHE A CD2   1 
ATOM   1865 C CE1   . PHE A 1 264 ? 133.676 149.790 181.132 1.00 79.76  ? 264 PHE A CE1   1 
ATOM   1866 C CE2   . PHE A 1 264 ? 133.474 152.099 181.690 1.00 79.76  ? 264 PHE A CE2   1 
ATOM   1867 C CZ    . PHE A 1 264 ? 133.015 150.993 181.009 1.00 79.76  ? 264 PHE A CZ    1 
ATOM   1868 N N     . MET A 1 265 ? 139.188 149.636 184.377 1.00 79.64  ? 265 MET A N     1 
ATOM   1869 C CA    . MET A 1 265 ? 140.388 149.828 185.180 1.00 79.64  ? 265 MET A CA    1 
ATOM   1870 C C     . MET A 1 265 ? 140.629 151.286 185.541 1.00 79.64  ? 265 MET A C     1 
ATOM   1871 O O     . MET A 1 265 ? 141.616 151.587 186.221 1.00 79.64  ? 265 MET A O     1 
ATOM   1872 C CB    . MET A 1 265 ? 141.608 149.262 184.453 1.00 79.64  ? 265 MET A CB    1 
ATOM   1873 C CG    . MET A 1 265 ? 141.694 147.751 184.521 1.00 79.64  ? 265 MET A CG    1 
ATOM   1874 S SD    . MET A 1 265 ? 140.471 146.959 183.471 1.00 79.64  ? 265 MET A SD    1 
ATOM   1875 C CE    . MET A 1 265 ? 141.195 147.262 181.873 1.00 79.64  ? 265 MET A CE    1 
ATOM   1876 N N     . GLU A 1 266 ? 139.759 152.192 185.101 1.00 92.26  ? 266 GLU A N     1 
ATOM   1877 C CA    . GLU A 1 266 ? 139.760 153.570 185.568 1.00 92.26  ? 266 GLU A CA    1 
ATOM   1878 C C     . GLU A 1 266 ? 138.786 153.773 186.718 1.00 92.26  ? 266 GLU A C     1 
ATOM   1879 O O     . GLU A 1 266 ? 138.567 154.911 187.144 1.00 92.26  ? 266 GLU A O     1 
ATOM   1880 C CB    . GLU A 1 266 ? 139.428 154.527 184.420 1.00 92.26  ? 266 GLU A CB    1 
ATOM   1881 C CG    . GLU A 1 266 ? 138.158 154.184 183.655 1.00 92.26  ? 266 GLU A CG    1 
ATOM   1882 C CD    . GLU A 1 266 ? 137.765 155.262 182.660 1.00 92.26  ? 266 GLU A CD    1 
ATOM   1883 O OE1   . GLU A 1 266 ? 138.346 155.298 181.555 1.00 92.26  ? 266 GLU A OE1   1 
ATOM   1884 O OE2   . GLU A 1 266 ? 136.876 156.078 182.985 1.00 92.26  ? 266 GLU A OE2   1 
ATOM   1885 N N     . ASP A 1 267 ? 138.201 152.694 187.227 1.00 95.30  ? 267 ASP A N     1 
ATOM   1886 C CA    . ASP A 1 267 ? 137.250 152.755 188.324 1.00 95.30  ? 267 ASP A CA    1 
ATOM   1887 C C     . ASP A 1 267 ? 137.964 152.670 189.670 1.00 95.30  ? 267 ASP A C     1 
ATOM   1888 O O     . ASP A 1 267 ? 139.071 152.139 189.785 1.00 95.30  ? 267 ASP A O     1 
ATOM   1889 C CB    . ASP A 1 267 ? 136.223 151.629 188.208 1.00 95.30  ? 267 ASP A CB    1 
ATOM   1890 C CG    . ASP A 1 267 ? 135.350 151.762 186.980 1.00 95.30  ? 267 ASP A CG    1 
ATOM   1891 O OD1   . ASP A 1 267 ? 135.198 152.895 186.477 1.00 95.30  ? 267 ASP A OD1   1 
ATOM   1892 O OD2   . ASP A 1 267 ? 134.801 150.736 186.526 1.00 95.30  ? 267 ASP A OD2   1 
ATOM   1893 N N     . GLU A 1 268 ? 137.311 153.208 190.694 1.00 103.50 ? 268 GLU A N     1 
ATOM   1894 C CA    . GLU A 1 268 ? 137.840 153.164 192.046 1.00 103.50 ? 268 GLU A CA    1 
ATOM   1895 C C     . GLU A 1 268 ? 137.414 151.875 192.744 1.00 103.50 ? 268 GLU A C     1 
ATOM   1896 O O     . GLU A 1 268 ? 136.522 151.153 192.291 1.00 103.50 ? 268 GLU A O     1 
ATOM   1897 C CB    . GLU A 1 268 ? 137.383 154.386 192.840 1.00 103.50 ? 268 GLU A CB    1 
ATOM   1898 C CG    . GLU A 1 268 ? 138.107 155.665 192.460 1.00 103.50 ? 268 GLU A CG    1 
ATOM   1899 C CD    . GLU A 1 268 ? 139.595 155.454 192.250 1.00 103.50 ? 268 GLU A CD    1 
ATOM   1900 O OE1   . GLU A 1 268 ? 140.277 155.043 193.212 1.00 103.50 ? 268 GLU A OE1   1 
ATOM   1901 O OE2   . GLU A 1 268 ? 140.082 155.693 191.124 1.00 103.50 ? 268 GLU A OE2   1 
ATOM   1902 N N     . GLU A 1 269 ? 138.066 151.597 193.876 1.00 99.73  ? 269 GLU A N     1 
ATOM   1903 C CA    . GLU A 1 269 ? 137.863 150.323 194.557 1.00 99.73  ? 269 GLU A CA    1 
ATOM   1904 C C     . GLU A 1 269 ? 136.424 150.165 195.033 1.00 99.73  ? 269 GLU A C     1 
ATOM   1905 O O     . GLU A 1 269 ? 135.822 149.099 194.871 1.00 99.73  ? 269 GLU A O     1 
ATOM   1906 C CB    . GLU A 1 269 ? 138.836 150.197 195.730 1.00 99.73  ? 269 GLU A CB    1 
ATOM   1907 C CG    . GLU A 1 269 ? 140.300 150.124 195.321 1.00 99.73  ? 269 GLU A CG    1 
ATOM   1908 C CD    . GLU A 1 269 ? 140.932 151.493 195.161 1.00 99.73  ? 269 GLU A CD    1 
ATOM   1909 O OE1   . GLU A 1 269 ? 140.372 152.323 194.415 1.00 99.73  ? 269 GLU A OE1   1 
ATOM   1910 O OE2   . GLU A 1 269 ? 141.989 151.741 195.778 1.00 99.73  ? 269 GLU A OE2   1 
ATOM   1911 N N     . ALA A 1 270 ? 135.856 151.217 195.626 1.00 105.57 ? 270 ALA A N     1 
ATOM   1912 C CA    . ALA A 1 270 ? 134.515 151.112 196.194 1.00 105.57 ? 270 ALA A CA    1 
ATOM   1913 C C     . ALA A 1 270 ? 133.478 150.816 195.116 1.00 105.57 ? 270 ALA A C     1 
ATOM   1914 O O     . ALA A 1 270 ? 132.627 149.932 195.279 1.00 105.57 ? 270 ALA A O     1 
ATOM   1915 C CB    . ALA A 1 270 ? 134.164 152.394 196.948 1.00 105.57 ? 270 ALA A CB    1 
ATOM   1916 N N     . GLU A 1 271 ? 133.538 151.541 193.997 1.00 101.27 ? 271 GLU A N     1 
ATOM   1917 C CA    . GLU A 1 271 ? 132.579 151.293 192.927 1.00 101.27 ? 271 GLU A CA    1 
ATOM   1918 C C     . GLU A 1 271 ? 132.853 149.970 192.223 1.00 101.27 ? 271 GLU A C     1 
ATOM   1919 O O     . GLU A 1 271 ? 131.920 149.346 191.708 1.00 101.27 ? 271 GLU A O     1 
ATOM   1920 C CB    . GLU A 1 271 ? 132.566 152.461 191.937 1.00 101.27 ? 271 GLU A CB    1 
ATOM   1921 C CG    . GLU A 1 271 ? 133.845 152.676 191.152 1.00 101.27 ? 271 GLU A CG    1 
ATOM   1922 C CD    . GLU A 1 271 ? 133.764 153.894 190.246 1.00 101.27 ? 271 GLU A CD    1 
ATOM   1923 O OE1   . GLU A 1 271 ? 132.718 154.577 190.252 1.00 101.27 ? 271 GLU A OE1   1 
ATOM   1924 O OE2   . GLU A 1 271 ? 134.744 154.176 189.529 1.00 101.27 ? 271 GLU A OE2   1 
ATOM   1925 N N     . VAL A 1 272 ? 134.106 149.510 192.208 1.00 101.08 ? 272 VAL A N     1 
ATOM   1926 C CA    . VAL A 1 272 ? 134.387 148.160 191.721 1.00 101.08 ? 272 VAL A CA    1 
ATOM   1927 C C     . VAL A 1 272 ? 133.681 147.129 192.594 1.00 101.08 ? 272 VAL A C     1 
ATOM   1928 O O     . VAL A 1 272 ? 133.066 146.178 192.094 1.00 101.08 ? 272 VAL A O     1 
ATOM   1929 C CB    . VAL A 1 272 ? 135.905 147.912 191.660 1.00 101.08 ? 272 VAL A CB    1 
ATOM   1930 C CG1   . VAL A 1 272 ? 136.204 146.419 191.648 1.00 101.08 ? 272 VAL A CG1   1 
ATOM   1931 C CG2   . VAL A 1 272 ? 136.500 148.579 190.431 1.00 101.08 ? 272 VAL A CG2   1 
ATOM   1932 N N     . ASN A 1 273 ? 133.757 147.307 193.916 1.00 99.75  ? 273 ASN A N     1 
ATOM   1933 C CA    . ASN A 1 273 ? 133.047 146.412 194.827 1.00 99.75  ? 273 ASN A CA    1 
ATOM   1934 C C     . ASN A 1 273 ? 131.546 146.459 194.581 1.00 99.75  ? 273 ASN A C     1 
ATOM   1935 O O     . ASN A 1 273 ? 130.868 145.422 194.594 1.00 99.75  ? 273 ASN A O     1 
ATOM   1936 C CB    . ASN A 1 273 ? 133.344 146.776 196.284 1.00 99.75  ? 273 ASN A CB    1 
ATOM   1937 C CG    . ASN A 1 273 ? 134.801 146.598 196.655 1.00 99.75  ? 273 ASN A CG    1 
ATOM   1938 O OD1   . ASN A 1 273 ? 135.322 145.486 196.663 1.00 99.75  ? 273 ASN A OD1   1 
ATOM   1939 N ND2   . ASN A 1 273 ? 135.472 147.699 196.948 1.00 99.75  ? 273 ASN A ND2   1 
ATOM   1940 N N     . VAL A 1 274 ? 131.009 147.662 194.371 1.00 98.95  ? 274 VAL A N     1 
ATOM   1941 C CA    . VAL A 1 274 ? 129.582 147.806 194.095 1.00 98.95  ? 274 VAL A CA    1 
ATOM   1942 C C     . VAL A 1 274 ? 129.211 147.056 192.820 1.00 98.95  ? 274 VAL A C     1 
ATOM   1943 O O     . VAL A 1 274 ? 128.179 146.375 192.758 1.00 98.95  ? 274 VAL A O     1 
ATOM   1944 C CB    . VAL A 1 274 ? 129.206 149.297 194.020 1.00 98.95  ? 274 VAL A CB    1 
ATOM   1945 C CG1   . VAL A 1 274 ? 127.762 149.466 193.588 1.00 98.95  ? 274 VAL A CG1   1 
ATOM   1946 C CG2   . VAL A 1 274 ? 129.438 149.966 195.367 1.00 98.95  ? 274 VAL A CG2   1 
ATOM   1947 N N     . LYS A 1 275 ? 130.056 147.158 191.789 1.00 98.05  ? 275 LYS A N     1 
ATOM   1948 C CA    . LYS A 1 275 ? 129.831 146.420 190.550 1.00 98.05  ? 275 LYS A CA    1 
ATOM   1949 C C     . LYS A 1 275 ? 129.821 144.916 190.793 1.00 98.05  ? 275 LYS A C     1 
ATOM   1950 O O     . LYS A 1 275 ? 128.965 144.197 190.263 1.00 98.05  ? 275 LYS A O     1 
ATOM   1951 C CB    . LYS A 1 275 ? 130.913 146.773 189.529 1.00 98.05  ? 275 LYS A CB    1 
ATOM   1952 C CG    . LYS A 1 275 ? 130.857 148.190 188.993 1.00 98.05  ? 275 LYS A CG    1 
ATOM   1953 C CD    . LYS A 1 275 ? 129.512 148.491 188.374 1.00 98.05  ? 275 LYS A CD    1 
ATOM   1954 C CE    . LYS A 1 275 ? 129.468 147.996 186.943 1.00 98.05  ? 275 LYS A CE    1 
ATOM   1955 N NZ    . LYS A 1 275 ? 128.111 148.128 186.353 1.00 98.05  ? 275 LYS A NZ    1 
ATOM   1956 N N     . ILE A 1 276 ? 130.774 144.422 191.584 1.00 99.06  ? 276 ILE A N     1 
ATOM   1957 C CA    . ILE A 1 276 ? 130.875 142.982 191.811 1.00 99.06  ? 276 ILE A CA    1 
ATOM   1958 C C     . ILE A 1 276 ? 129.646 142.466 192.553 1.00 99.06  ? 276 ILE A C     1 
ATOM   1959 O O     . ILE A 1 276 ? 129.089 141.417 192.207 1.00 99.06  ? 276 ILE A O     1 
ATOM   1960 C CB    . ILE A 1 276 ? 132.174 142.637 192.559 1.00 99.06  ? 276 ILE A CB    1 
ATOM   1961 C CG1   . ILE A 1 276 ? 133.393 143.164 191.799 1.00 99.06  ? 276 ILE A CG1   1 
ATOM   1962 C CG2   . ILE A 1 276 ? 132.284 141.135 192.768 1.00 99.06  ? 276 ILE A CG2   1 
ATOM   1963 C CD1   . ILE A 1 276 ? 133.424 142.777 190.342 1.00 99.06  ? 276 ILE A CD1   1 
ATOM   1964 N N     . LYS A 1 277 ? 129.205 143.190 193.585 1.00 100.25 ? 277 LYS A N     1 
ATOM   1965 C CA    . LYS A 1 277 ? 128.003 142.759 194.302 1.00 100.25 ? 277 LYS A CA    1 
ATOM   1966 C C     . LYS A 1 277 ? 126.731 142.919 193.475 1.00 100.25 ? 277 LYS A C     1 
ATOM   1967 O O     . LYS A 1 277 ? 125.790 142.137 193.653 1.00 100.25 ? 277 LYS A O     1 
ATOM   1968 C CB    . LYS A 1 277 ? 127.862 143.471 195.656 1.00 100.25 ? 277 LYS A CB    1 
ATOM   1969 C CG    . LYS A 1 277 ? 129.143 143.739 196.454 1.00 100.25 ? 277 LYS A CG    1 
ATOM   1970 C CD    . LYS A 1 277 ? 130.135 142.572 196.355 1.00 100.25 ? 277 LYS A CD    1 
ATOM   1971 C CE    . LYS A 1 277 ? 131.490 142.897 196.955 1.00 100.25 ? 277 LYS A CE    1 
ATOM   1972 N NZ    . LYS A 1 277 ? 132.384 143.541 195.964 1.00 100.25 ? 277 LYS A NZ    1 
ATOM   1973 N N     . LYS A 1 278 ? 126.664 143.899 192.570 1.00 100.65 ? 278 LYS A N     1 
ATOM   1974 C CA    . LYS A 1 278 ? 125.482 143.972 191.718 1.00 100.65 ? 278 LYS A CA    1 
ATOM   1975 C C     . LYS A 1 278 ? 125.543 142.979 190.565 1.00 100.65 ? 278 LYS A C     1 
ATOM   1976 O O     . LYS A 1 278 ? 124.527 142.765 189.895 1.00 100.65 ? 278 LYS A O     1 
ATOM   1977 C CB    . LYS A 1 278 ? 125.284 145.384 191.163 1.00 100.65 ? 278 LYS A CB    1 
ATOM   1978 C CG    . LYS A 1 278 ? 126.264 145.780 190.077 1.00 100.65 ? 278 LYS A CG    1 
ATOM   1979 C CD    . LYS A 1 278 ? 125.749 146.974 189.291 1.00 100.65 ? 278 LYS A CD    1 
ATOM   1980 C CE    . LYS A 1 278 ? 125.711 148.228 190.145 1.00 100.65 ? 278 LYS A CE    1 
ATOM   1981 N NZ    . LYS A 1 278 ? 127.077 148.668 190.527 1.00 100.65 ? 278 LYS A NZ    1 
ATOM   1982 N N     . ALA A 1 279 ? 126.702 142.375 190.318 1.00 99.04  ? 279 ALA A N     1 
ATOM   1983 C CA    . ALA A 1 279 ? 126.826 141.409 189.236 1.00 99.04  ? 279 ALA A CA    1 
ATOM   1984 C C     . ALA A 1 279 ? 126.023 140.150 189.542 1.00 99.04  ? 279 ALA A C     1 
ATOM   1985 O O     . ALA A 1 279 ? 125.960 139.694 190.687 1.00 99.04  ? 279 ALA A O     1 
ATOM   1986 C CB    . ALA A 1 279 ? 128.294 141.056 189.003 1.00 99.04  ? 279 ALA A CB    1 
ATOM   1987 N N     . TYR A 1 280 ? 125.410 139.587 188.504 1.00 106.92 ? 280 TYR A N     1 
ATOM   1988 C CA    . TYR A 1 280 ? 124.570 138.410 188.670 1.00 106.92 ? 280 TYR A CA    1 
ATOM   1989 C C     . TYR A 1 280 ? 125.426 137.172 188.910 1.00 106.92 ? 280 TYR A C     1 
ATOM   1990 O O     . TYR A 1 280 ? 126.389 136.918 188.181 1.00 106.92 ? 280 TYR A O     1 
ATOM   1991 C CB    . TYR A 1 280 ? 123.687 138.221 187.437 1.00 106.92 ? 280 TYR A CB    1 
ATOM   1992 C CG    . TYR A 1 280 ? 122.799 137.000 187.480 1.00 106.92 ? 280 TYR A CG    1 
ATOM   1993 C CD1   . TYR A 1 280 ? 121.736 136.921 188.370 1.00 106.92 ? 280 TYR A CD1   1 
ATOM   1994 C CD2   . TYR A 1 280 ? 123.014 135.933 186.619 1.00 106.92 ? 280 TYR A CD2   1 
ATOM   1995 C CE1   . TYR A 1 280 ? 120.919 135.807 188.408 1.00 106.92 ? 280 TYR A CE1   1 
ATOM   1996 C CE2   . TYR A 1 280 ? 122.202 134.818 186.647 1.00 106.92 ? 280 TYR A CE2   1 
ATOM   1997 C CZ    . TYR A 1 280 ? 121.157 134.759 187.544 1.00 106.92 ? 280 TYR A CZ    1 
ATOM   1998 O OH    . TYR A 1 280 ? 120.346 133.647 187.576 1.00 106.92 ? 280 TYR A OH    1 
ATOM   1999 N N     . CYS A 1 281 ? 125.073 136.403 189.938 1.00 106.00 ? 281 CYS A N     1 
ATOM   2000 C CA    . CYS A 1 281 ? 125.800 135.189 190.285 1.00 106.00 ? 281 CYS A CA    1 
ATOM   2001 C C     . CYS A 1 281 ? 124.899 134.237 191.061 1.00 106.00 ? 281 CYS A C     1 
ATOM   2002 O O     . CYS A 1 281 ? 124.819 134.322 192.293 1.00 106.00 ? 281 CYS A O     1 
ATOM   2003 C CB    . CYS A 1 281 ? 127.048 135.521 191.104 1.00 106.00 ? 281 CYS A CB    1 
ATOM   2004 S SG    . CYS A 1 281 ? 128.263 134.186 191.191 1.00 106.00 ? 281 CYS A SG    1 
ATOM   2005 N N     . PRO A 1 282 ? 124.210 133.322 190.386 1.00 105.78 ? 282 PRO A N     1 
ATOM   2006 C CA    . PRO A 1 282 ? 123.343 132.377 191.089 1.00 105.78 ? 282 PRO A CA    1 
ATOM   2007 C C     . PRO A 1 282 ? 124.142 131.202 191.621 1.00 105.78 ? 282 PRO A C     1 
ATOM   2008 O O     . PRO A 1 282 ? 124.994 130.645 190.913 1.00 105.78 ? 282 PRO A O     1 
ATOM   2009 C CB    . PRO A 1 282 ? 122.353 131.937 190.003 1.00 105.78 ? 282 PRO A CB    1 
ATOM   2010 C CG    . PRO A 1 282 ? 123.120 132.068 188.725 1.00 105.78 ? 282 PRO A CG    1 
ATOM   2011 C CD    . PRO A 1 282 ? 124.194 133.116 188.927 1.00 105.78 ? 282 PRO A CD    1 
ATOM   2012 N N     . PRO A 1 283 ? 123.906 130.802 192.869 1.00 100.18 ? 283 PRO A N     1 
ATOM   2013 C CA    . PRO A 1 283 ? 124.651 129.671 193.431 1.00 100.18 ? 283 PRO A CA    1 
ATOM   2014 C C     . PRO A 1 283 ? 124.306 128.363 192.736 1.00 100.18 ? 283 PRO A C     1 
ATOM   2015 O O     . PRO A 1 283 ? 123.185 128.158 192.261 1.00 100.18 ? 283 PRO A O     1 
ATOM   2016 C CB    . PRO A 1 283 ? 124.216 129.650 194.901 1.00 100.18 ? 283 PRO A CB    1 
ATOM   2017 C CG    . PRO A 1 283 ? 122.903 130.354 194.924 1.00 100.18 ? 283 PRO A CG    1 
ATOM   2018 C CD    . PRO A 1 283 ? 122.945 131.375 193.826 1.00 100.18 ? 283 PRO A CD    1 
ATOM   2019 N N     . LYS A 1 284 ? 125.300 127.474 192.684 1.00 102.14 ? 284 LYS A N     1 
ATOM   2020 C CA    . LYS A 1 284 ? 125.155 126.139 192.100 1.00 102.14 ? 284 LYS A CA    1 
ATOM   2021 C C     . LYS A 1 284 ? 124.675 126.202 190.650 1.00 102.14 ? 284 LYS A C     1 
ATOM   2022 O O     . LYS A 1 284 ? 123.861 125.388 190.210 1.00 102.14 ? 284 LYS A O     1 
ATOM   2023 C CB    . LYS A 1 284 ? 124.223 125.269 192.946 1.00 102.14 ? 284 LYS A CB    1 
ATOM   2024 C CG    . LYS A 1 284 ? 124.644 125.159 194.403 1.00 102.14 ? 284 LYS A CG    1 
ATOM   2025 C CD    . LYS A 1 284 ? 123.778 124.164 195.157 1.00 102.14 ? 284 LYS A CD    1 
ATOM   2026 C CE    . LYS A 1 284 ? 124.102 124.168 196.641 1.00 102.14 ? 284 LYS A CE    1 
ATOM   2027 N NZ    . LYS A 1 284 ? 123.257 123.203 197.395 1.00 102.14 ? 284 LYS A NZ    1 
ATOM   2028 N N     . VAL A 1 285 ? 125.183 127.176 189.900 1.00 102.60 ? 285 VAL A N     1 
ATOM   2029 C CA    . VAL A 1 285 ? 124.892 127.319 188.477 1.00 102.60 ? 285 VAL A CA    1 
ATOM   2030 C C     . VAL A 1 285 ? 126.221 127.376 187.736 1.00 102.60 ? 285 VAL A C     1 
ATOM   2031 O O     . VAL A 1 285 ? 127.064 128.233 188.029 1.00 102.60 ? 285 VAL A O     1 
ATOM   2032 C CB    . VAL A 1 285 ? 124.042 128.566 188.188 1.00 102.60 ? 285 VAL A CB    1 
ATOM   2033 C CG1   . VAL A 1 285 ? 123.958 128.816 186.692 1.00 102.60 ? 285 VAL A CG1   1 
ATOM   2034 C CG2   . VAL A 1 285 ? 122.652 128.406 188.783 1.00 102.60 ? 285 VAL A CG2   1 
ATOM   2035 N N     . VAL A 1 286 ? 126.400 126.479 186.768 1.00 103.60 ? 286 VAL A N     1 
ATOM   2036 C CA    . VAL A 1 286 ? 127.704 126.319 186.128 1.00 103.60 ? 286 VAL A CA    1 
ATOM   2037 C C     . VAL A 1 286 ? 127.943 127.415 185.097 1.00 103.60 ? 286 VAL A C     1 
ATOM   2038 O O     . VAL A 1 286 ? 128.864 128.228 185.232 1.00 103.60 ? 286 VAL A O     1 
ATOM   2039 C CB    . VAL A 1 286 ? 127.820 124.922 185.492 1.00 103.60 ? 286 VAL A CB    1 
ATOM   2040 C CG1   . VAL A 1 286 ? 129.172 124.758 184.814 1.00 103.60 ? 286 VAL A CG1   1 
ATOM   2041 C CG2   . VAL A 1 286 ? 127.604 123.846 186.540 1.00 103.60 ? 286 VAL A CG2   1 
ATOM   2042 N N     . GLU A 1 287 ? 127.118 127.455 184.058 1.00 107.04 ? 287 GLU A N     1 
ATOM   2043 C CA    . GLU A 1 287 ? 127.299 128.383 182.952 1.00 107.04 ? 287 GLU A CA    1 
ATOM   2044 C C     . GLU A 1 287 ? 126.334 129.554 183.080 1.00 107.04 ? 287 GLU A C     1 
ATOM   2045 O O     . GLU A 1 287 ? 125.375 129.526 183.856 1.00 107.04 ? 287 GLU A O     1 
ATOM   2046 C CB    . GLU A 1 287 ? 127.107 127.673 181.607 1.00 107.04 ? 287 GLU A CB    1 
ATOM   2047 C CG    . GLU A 1 287 ? 125.680 127.236 181.327 1.00 107.04 ? 287 GLU A CG    1 
ATOM   2048 C CD    . GLU A 1 287 ? 125.608 126.113 180.311 1.00 107.04 ? 287 GLU A CD    1 
ATOM   2049 O OE1   . GLU A 1 287 ? 126.210 125.047 180.558 1.00 107.04 ? 287 GLU A OE1   1 
ATOM   2050 O OE2   . GLU A 1 287 ? 124.951 126.297 179.265 1.00 107.04 ? 287 GLU A OE2   1 
ATOM   2051 N N     . GLY A 1 288 ? 126.602 130.595 182.296 1.00 107.03 ? 288 GLY A N     1 
ATOM   2052 C CA    . GLY A 1 288 ? 125.807 131.802 182.368 1.00 107.03 ? 288 GLY A CA    1 
ATOM   2053 C C     . GLY A 1 288 ? 126.078 132.662 183.578 1.00 107.03 ? 288 GLY A C     1 
ATOM   2054 O O     . GLY A 1 288 ? 125.233 133.489 183.935 1.00 107.03 ? 288 GLY A O     1 
ATOM   2055 N N     . ASN A 1 289 ? 127.227 132.491 184.226 1.00 107.08 ? 289 ASN A N     1 
ATOM   2056 C CA    . ASN A 1 289 ? 127.578 133.284 185.399 1.00 107.08 ? 289 ASN A CA    1 
ATOM   2057 C C     . ASN A 1 289 ? 128.694 134.252 185.037 1.00 107.08 ? 289 ASN A C     1 
ATOM   2058 O O     . ASN A 1 289 ? 129.851 133.825 184.875 1.00 107.08 ? 289 ASN A O     1 
ATOM   2059 C CB    . ASN A 1 289 ? 128.004 132.381 186.557 1.00 107.08 ? 289 ASN A CB    1 
ATOM   2060 C CG    . ASN A 1 289 ? 128.103 133.127 187.878 1.00 107.08 ? 289 ASN A CG    1 
ATOM   2061 O OD1   . ASN A 1 289 ? 128.351 134.333 187.913 1.00 107.08 ? 289 ASN A OD1   1 
ATOM   2062 N ND2   . ASN A 1 289 ? 127.898 132.409 188.977 1.00 107.08 ? 289 ASN A ND2   1 
ATOM   2063 N N     . PRO A 1 290 ? 128.395 135.544 184.877 1.00 100.20 ? 290 PRO A N     1 
ATOM   2064 C CA    . PRO A 1 290 ? 129.468 136.511 184.603 1.00 100.20 ? 290 PRO A CA    1 
ATOM   2065 C C     . PRO A 1 290 ? 130.579 136.484 185.635 1.00 100.20 ? 290 PRO A C     1 
ATOM   2066 O O     . PRO A 1 290 ? 131.750 136.635 185.273 1.00 100.20 ? 290 PRO A O     1 
ATOM   2067 C CB    . PRO A 1 290 ? 128.733 137.859 184.611 1.00 100.20 ? 290 PRO A CB    1 
ATOM   2068 C CG    . PRO A 1 290 ? 127.268 137.538 184.446 1.00 100.20 ? 290 PRO A CG    1 
ATOM   2069 C CD    . PRO A 1 290 ? 127.080 136.051 184.458 1.00 100.20 ? 290 PRO A CD    1 
ATOM   2070 N N     . CYS A 1 291 ? 130.248 136.296 186.915 1.00 102.26 ? 291 CYS A N     1 
ATOM   2071 C CA    . CYS A 1 291 ? 131.278 136.277 187.949 1.00 102.26 ? 291 CYS A CA    1 
ATOM   2072 C C     . CYS A 1 291 ? 132.210 135.082 187.782 1.00 102.26 ? 291 CYS A C     1 
ATOM   2073 O O     . CYS A 1 291 ? 133.436 135.221 187.877 1.00 102.26 ? 291 CYS A O     1 
ATOM   2074 C CB    . CYS A 1 291 ? 130.631 136.271 189.334 1.00 102.26 ? 291 CYS A CB    1 
ATOM   2075 S SG    . CYS A 1 291 ? 129.504 137.653 189.627 1.00 102.26 ? 291 CYS A SG    1 
ATOM   2076 N N     . LEU A 1 292 ? 131.647 133.897 187.532 1.00 100.90 ? 292 LEU A N     1 
ATOM   2077 C CA    . LEU A 1 292 ? 132.481 132.716 187.328 1.00 100.90 ? 292 LEU A CA    1 
ATOM   2078 C C     . LEU A 1 292 ? 133.336 132.853 186.075 1.00 100.90 ? 292 LEU A C     1 
ATOM   2079 O O     . LEU A 1 292 ? 134.513 132.467 186.069 1.00 100.90 ? 292 LEU A O     1 
ATOM   2080 C CB    . LEU A 1 292 ? 131.612 131.462 187.249 1.00 100.90 ? 292 LEU A CB    1 
ATOM   2081 C CG    . LEU A 1 292 ? 130.943 131.013 188.549 1.00 100.90 ? 292 LEU A CG    1 
ATOM   2082 C CD1   . LEU A 1 292 ? 130.008 129.841 188.292 1.00 100.90 ? 292 LEU A CD1   1 
ATOM   2083 C CD2   . LEU A 1 292 ? 131.988 130.653 189.594 1.00 100.90 ? 292 LEU A CD2   1 
ATOM   2084 N N     . GLU A 1 293 ? 132.760 133.394 184.998 1.00 91.85  ? 293 GLU A N     1 
ATOM   2085 C CA    . GLU A 1 293 ? 133.539 133.584 183.779 1.00 91.85  ? 293 GLU A CA    1 
ATOM   2086 C C     . GLU A 1 293 ? 134.659 134.595 183.991 1.00 91.85  ? 293 GLU A C     1 
ATOM   2087 O O     . GLU A 1 293 ? 135.775 134.403 183.494 1.00 91.85  ? 293 GLU A O     1 
ATOM   2088 C CB    . GLU A 1 293 ? 132.628 134.006 182.629 1.00 91.85  ? 293 GLU A CB    1 
ATOM   2089 C CG    . GLU A 1 293 ? 132.242 132.851 181.716 1.00 91.85  ? 293 GLU A CG    1 
ATOM   2090 C CD    . GLU A 1 293 ? 131.449 133.296 180.507 1.00 91.85  ? 293 GLU A CD    1 
ATOM   2091 O OE1   . GLU A 1 293 ? 131.026 134.468 180.472 1.00 91.85  ? 293 GLU A OE1   1 
ATOM   2092 O OE2   . GLU A 1 293 ? 131.251 132.473 179.588 1.00 91.85  ? 293 GLU A OE2   1 
ATOM   2093 N N     . TYR A 1 294 ? 134.385 135.677 184.725 1.00 90.05  ? 294 TYR A N     1 
ATOM   2094 C CA    . TYR A 1 294 ? 135.434 136.636 185.050 1.00 90.05  ? 294 TYR A CA    1 
ATOM   2095 C C     . TYR A 1 294 ? 136.536 135.976 185.862 1.00 90.05  ? 294 TYR A C     1 
ATOM   2096 O O     . TYR A 1 294 ? 137.724 136.187 185.601 1.00 90.05  ? 294 TYR A O     1 
ATOM   2097 C CB    . TYR A 1 294 ? 134.859 137.830 185.814 1.00 90.05  ? 294 TYR A CB    1 
ATOM   2098 C CG    . TYR A 1 294 ? 134.118 138.830 184.959 1.00 90.05  ? 294 TYR A CG    1 
ATOM   2099 C CD1   . TYR A 1 294 ? 133.825 138.560 183.630 1.00 90.05  ? 294 TYR A CD1   1 
ATOM   2100 C CD2   . TYR A 1 294 ? 133.742 140.061 185.476 1.00 90.05  ? 294 TYR A CD2   1 
ATOM   2101 C CE1   . TYR A 1 294 ? 133.152 139.477 182.849 1.00 90.05  ? 294 TYR A CE1   1 
ATOM   2102 C CE2   . TYR A 1 294 ? 133.076 140.986 184.700 1.00 90.05  ? 294 TYR A CE2   1 
ATOM   2103 C CZ    . TYR A 1 294 ? 132.782 140.689 183.387 1.00 90.05  ? 294 TYR A CZ    1 
ATOM   2104 O OH    . TYR A 1 294 ? 132.116 141.608 182.609 1.00 90.05  ? 294 TYR A OH    1 
ATOM   2105 N N     . ILE A 1 295 ? 136.157 135.174 186.859 1.00 88.50  ? 295 ILE A N     1 
ATOM   2106 C CA    . ILE A 1 295 ? 137.144 134.408 187.618 1.00 88.50  ? 295 ILE A CA    1 
ATOM   2107 C C     . ILE A 1 295 ? 138.043 133.635 186.663 1.00 88.50  ? 295 ILE A C     1 
ATOM   2108 O O     . ILE A 1 295 ? 139.257 133.871 186.589 1.00 88.50  ? 295 ILE A O     1 
ATOM   2109 C CB    . ILE A 1 295 ? 136.445 133.464 188.612 1.00 88.50  ? 295 ILE A CB    1 
ATOM   2110 C CG1   . ILE A 1 295 ? 135.861 134.254 189.782 1.00 88.50  ? 295 ILE A CG1   1 
ATOM   2111 C CG2   . ILE A 1 295 ? 137.409 132.396 189.113 1.00 88.50  ? 295 ILE A CG2   1 
ATOM   2112 C CD1   . ILE A 1 295 ? 135.089 133.403 190.761 1.00 88.50  ? 295 ILE A CD1   1 
ATOM   2113 N N     . LYS A 1 296 ? 137.424 132.770 185.852 1.00 88.15  ? 296 LYS A N     1 
ATOM   2114 C CA    . LYS A 1 296 ? 138.167 131.834 185.014 1.00 88.15  ? 296 LYS A CA    1 
ATOM   2115 C C     . LYS A 1 296 ? 139.059 132.552 184.009 1.00 88.15  ? 296 LYS A C     1 
ATOM   2116 O O     . LYS A 1 296 ? 140.174 132.098 183.728 1.00 88.15  ? 296 LYS A O     1 
ATOM   2117 C CB    . LYS A 1 296 ? 137.192 130.903 184.292 1.00 88.15  ? 296 LYS A CB    1 
ATOM   2118 C CG    . LYS A 1 296 ? 137.850 129.885 183.374 1.00 88.15  ? 296 LYS A CG    1 
ATOM   2119 C CD    . LYS A 1 296 ? 136.810 129.020 182.681 1.00 88.15  ? 296 LYS A CD    1 
ATOM   2120 C CE    . LYS A 1 296 ? 137.462 127.942 181.832 1.00 88.15  ? 296 LYS A CE    1 
ATOM   2121 N NZ    . LYS A 1 296 ? 138.193 128.520 180.672 1.00 88.15  ? 296 LYS A NZ    1 
ATOM   2122 N N     . TYR A 1 297 ? 138.588 133.663 183.445 1.00 83.75  ? 297 TYR A N     1 
ATOM   2123 C CA    . TYR A 1 297 ? 139.332 134.331 182.386 1.00 83.75  ? 297 TYR A CA    1 
ATOM   2124 C C     . TYR A 1 297 ? 140.269 135.425 182.883 1.00 83.75  ? 297 TYR A C     1 
ATOM   2125 O O     . TYR A 1 297 ? 141.087 135.911 182.095 1.00 83.75  ? 297 TYR A O     1 
ATOM   2126 C CB    . TYR A 1 297 ? 138.367 134.927 181.356 1.00 83.75  ? 297 TYR A CB    1 
ATOM   2127 C CG    . TYR A 1 297 ? 137.753 133.901 180.434 1.00 83.75  ? 297 TYR A CG    1 
ATOM   2128 C CD1   . TYR A 1 297 ? 138.482 133.359 179.387 1.00 83.75  ? 297 TYR A CD1   1 
ATOM   2129 C CD2   . TYR A 1 297 ? 136.443 133.478 180.607 1.00 83.75  ? 297 TYR A CD2   1 
ATOM   2130 C CE1   . TYR A 1 297 ? 137.927 132.423 178.541 1.00 83.75  ? 297 TYR A CE1   1 
ATOM   2131 C CE2   . TYR A 1 297 ? 135.879 132.542 179.765 1.00 83.75  ? 297 TYR A CE2   1 
ATOM   2132 C CZ    . TYR A 1 297 ? 136.626 132.018 178.735 1.00 83.75  ? 297 TYR A CZ    1 
ATOM   2133 O OH    . TYR A 1 297 ? 136.069 131.085 177.892 1.00 83.75  ? 297 TYR A OH    1 
ATOM   2134 N N     . LEU A 1 298 ? 140.185 135.829 184.149 1.00 78.45  ? 298 LEU A N     1 
ATOM   2135 C CA    . LEU A 1 298 ? 141.032 136.908 184.637 1.00 78.45  ? 298 LEU A CA    1 
ATOM   2136 C C     . LEU A 1 298 ? 141.953 136.491 185.772 1.00 78.45  ? 298 LEU A C     1 
ATOM   2137 O O     . LEU A 1 298 ? 143.167 136.704 185.679 1.00 78.45  ? 298 LEU A O     1 
ATOM   2138 C CB    . LEU A 1 298 ? 140.162 138.096 185.079 1.00 78.45  ? 298 LEU A CB    1 
ATOM   2139 C CG    . LEU A 1 298 ? 139.085 138.543 184.087 1.00 78.45  ? 298 LEU A CG    1 
ATOM   2140 C CD1   . LEU A 1 298 ? 138.087 139.463 184.768 1.00 78.45  ? 298 LEU A CD1   1 
ATOM   2141 C CD2   . LEU A 1 298 ? 139.704 139.218 182.874 1.00 78.45  ? 298 LEU A CD2   1 
ATOM   2142 N N     . ILE A 1 299 ? 141.426 135.903 186.845 1.00 83.71  ? 299 ILE A N     1 
ATOM   2143 C CA    . ILE A 1 299 ? 142.249 135.761 188.045 1.00 83.71  ? 299 ILE A CA    1 
ATOM   2144 C C     . ILE A 1 299 ? 143.007 134.443 188.051 1.00 83.71  ? 299 ILE A C     1 
ATOM   2145 O O     . ILE A 1 299 ? 144.158 134.388 188.493 1.00 83.71  ? 299 ILE A O     1 
ATOM   2146 C CB    . ILE A 1 299 ? 141.397 135.930 189.319 1.00 83.71  ? 299 ILE A CB    1 
ATOM   2147 C CG1   . ILE A 1 299 ? 140.215 134.965 189.325 1.00 83.71  ? 299 ILE A CG1   1 
ATOM   2148 C CG2   . ILE A 1 299 ? 140.910 137.361 189.445 1.00 83.71  ? 299 ILE A CG2   1 
ATOM   2149 C CD1   . ILE A 1 299 ? 139.335 135.113 190.536 1.00 83.71  ? 299 ILE A CD1   1 
ATOM   2150 N N     . LEU A 1 300 ? 142.384 133.368 187.577 1.00 87.47  ? 300 LEU A N     1 
ATOM   2151 C CA    . LEU A 1 300 ? 143.099 132.100 187.471 1.00 87.47  ? 300 LEU A CA    1 
ATOM   2152 C C     . LEU A 1 300 ? 144.288 132.177 186.520 1.00 87.47  ? 300 LEU A C     1 
ATOM   2153 O O     . LEU A 1 300 ? 145.396 131.799 186.932 1.00 87.47  ? 300 LEU A O     1 
ATOM   2154 C CB    . LEU A 1 300 ? 142.121 130.990 187.072 1.00 87.47  ? 300 LEU A CB    1 
ATOM   2155 C CG    . LEU A 1 300 ? 141.059 130.681 188.128 1.00 87.47  ? 300 LEU A CG    1 
ATOM   2156 C CD1   . LEU A 1 300 ? 140.063 129.680 187.593 1.00 87.47  ? 300 LEU A CD1   1 
ATOM   2157 C CD2   . LEU A 1 300 ? 141.704 130.167 189.403 1.00 87.47  ? 300 LEU A CD2   1 
ATOM   2158 N N     . PRO A 1 301 ? 144.155 132.655 185.275 1.00 79.39  ? 301 PRO A N     1 
ATOM   2159 C CA    . PRO A 1 301 ? 145.339 132.700 184.400 1.00 79.39  ? 301 PRO A CA    1 
ATOM   2160 C C     . PRO A 1 301 ? 146.429 133.628 184.904 1.00 79.39  ? 301 PRO A C     1 
ATOM   2161 O O     . PRO A 1 301 ? 147.616 133.356 184.683 1.00 79.39  ? 301 PRO A O     1 
ATOM   2162 C CB    . PRO A 1 301 ? 144.764 133.177 183.057 1.00 79.39  ? 301 PRO A CB    1 
ATOM   2163 C CG    . PRO A 1 301 ? 143.288 132.931 183.151 1.00 79.39  ? 301 PRO A CG    1 
ATOM   2164 C CD    . PRO A 1 301 ? 142.966 133.181 184.584 1.00 79.39  ? 301 PRO A CD    1 
ATOM   2165 N N     . TRP A 1 302 ? 146.062 134.717 185.580 1.00 78.07  ? 302 TRP A N     1 
ATOM   2166 C CA    . TRP A 1 302 ? 147.056 135.697 186.007 1.00 78.07  ? 302 TRP A CA    1 
ATOM   2167 C C     . TRP A 1 302 ? 147.875 135.186 187.189 1.00 78.07  ? 302 TRP A C     1 
ATOM   2168 O O     . TRP A 1 302 ? 149.101 135.342 187.216 1.00 78.07  ? 302 TRP A O     1 
ATOM   2169 C CB    . TRP A 1 302 ? 146.367 137.019 186.352 1.00 78.07  ? 302 TRP A CB    1 
ATOM   2170 C CG    . TRP A 1 302 ? 147.317 138.141 186.647 1.00 78.07  ? 302 TRP A CG    1 
ATOM   2171 C CD1   . TRP A 1 302 ? 148.180 138.236 187.699 1.00 78.07  ? 302 TRP A CD1   1 
ATOM   2172 C CD2   . TRP A 1 302 ? 147.509 139.322 185.863 1.00 78.07  ? 302 TRP A CD2   1 
ATOM   2173 N NE1   . TRP A 1 302 ? 148.893 139.406 187.623 1.00 78.07  ? 302 TRP A NE1   1 
ATOM   2174 C CE2   . TRP A 1 302 ? 148.500 140.091 186.504 1.00 78.07  ? 302 TRP A CE2   1 
ATOM   2175 C CE3   . TRP A 1 302 ? 146.937 139.805 184.684 1.00 78.07  ? 302 TRP A CE3   1 
ATOM   2176 C CZ2   . TRP A 1 302 ? 148.929 141.316 186.005 1.00 78.07  ? 302 TRP A CZ2   1 
ATOM   2177 C CZ3   . TRP A 1 302 ? 147.365 141.020 184.191 1.00 78.07  ? 302 TRP A CZ3   1 
ATOM   2178 C CH2   . TRP A 1 302 ? 148.352 141.761 184.850 1.00 78.07  ? 302 TRP A CH2   1 
ATOM   2179 N N     . PHE A 1 303 ? 147.218 134.578 188.179 1.00 89.66  ? 303 PHE A N     1 
ATOM   2180 C CA    . PHE A 1 303 ? 147.865 134.263 189.445 1.00 89.66  ? 303 PHE A CA    1 
ATOM   2181 C C     . PHE A 1 303 ? 148.083 132.774 189.667 1.00 89.66  ? 303 PHE A C     1 
ATOM   2182 O O     . PHE A 1 303 ? 148.666 132.399 190.691 1.00 89.66  ? 303 PHE A O     1 
ATOM   2183 C CB    . PHE A 1 303 ? 147.054 134.838 190.612 1.00 89.66  ? 303 PHE A CB    1 
ATOM   2184 C CG    . PHE A 1 303 ? 147.300 136.296 190.858 1.00 89.66  ? 303 PHE A CG    1 
ATOM   2185 C CD1   . PHE A 1 303 ? 148.589 136.793 190.953 1.00 89.66  ? 303 PHE A CD1   1 
ATOM   2186 C CD2   . PHE A 1 303 ? 146.236 137.170 191.001 1.00 89.66  ? 303 PHE A CD2   1 
ATOM   2187 C CE1   . PHE A 1 303 ? 148.811 138.140 191.180 1.00 89.66  ? 303 PHE A CE1   1 
ATOM   2188 C CE2   . PHE A 1 303 ? 146.450 138.514 191.230 1.00 89.66  ? 303 PHE A CE2   1 
ATOM   2189 C CZ    . PHE A 1 303 ? 147.738 139.001 191.319 1.00 89.66  ? 303 PHE A CZ    1 
ATOM   2190 N N     . ASN A 1 304 ? 147.626 131.919 188.749 1.00 94.51  ? 304 ASN A N     1 
ATOM   2191 C CA    . ASN A 1 304 ? 147.803 130.476 188.842 1.00 94.51  ? 304 ASN A CA    1 
ATOM   2192 C C     . ASN A 1 304 ? 147.100 129.899 190.065 1.00 94.51  ? 304 ASN A C     1 
ATOM   2193 O O     . ASN A 1 304 ? 147.296 128.722 190.395 1.00 94.51  ? 304 ASN A O     1 
ATOM   2194 C CB    . ASN A 1 304 ? 149.292 130.113 188.863 1.00 94.51  ? 304 ASN A CB    1 
ATOM   2195 C CG    . ASN A 1 304 ? 150.057 130.702 187.700 1.00 94.51  ? 304 ASN A CG    1 
ATOM   2196 O OD1   . ASN A 1 304 ? 150.918 131.565 187.880 1.00 94.51  ? 304 ASN A OD1   1 
ATOM   2197 N ND2   . ASN A 1 304 ? 149.762 130.227 186.500 1.00 94.51  ? 304 ASN A ND2   1 
ATOM   2198 N N     . GLU A 1 305 ? 146.293 130.720 190.737 1.00 102.94 ? 305 GLU A N     1 
ATOM   2199 C CA    . GLU A 1 305 ? 145.576 130.314 191.939 1.00 102.94 ? 305 GLU A CA    1 
ATOM   2200 C C     . GLU A 1 305 ? 144.570 131.402 192.279 1.00 102.94 ? 305 GLU A C     1 
ATOM   2201 O O     . GLU A 1 305 ? 144.580 132.489 191.694 1.00 102.94 ? 305 GLU A O     1 
ATOM   2202 C CB    . GLU A 1 305 ? 146.527 130.052 193.115 1.00 102.94 ? 305 GLU A CB    1 
ATOM   2203 C CG    . GLU A 1 305 ? 147.490 131.200 193.418 1.00 102.94 ? 305 GLU A CG    1 
ATOM   2204 C CD    . GLU A 1 305 ? 146.907 132.248 194.347 1.00 102.94 ? 305 GLU A CD    1 
ATOM   2205 O OE1   . GLU A 1 305 ? 145.916 131.940 195.040 1.00 102.94 ? 305 GLU A OE1   1 
ATOM   2206 O OE2   . GLU A 1 305 ? 147.440 133.380 194.383 1.00 102.94 ? 305 GLU A OE2   1 
ATOM   2207 N N     . PHE A 1 306 ? 143.707 131.097 193.246 1.00 104.11 ? 306 PHE A N     1 
ATOM   2208 C CA    . PHE A 1 306 ? 142.687 132.032 193.707 1.00 104.11 ? 306 PHE A CA    1 
ATOM   2209 C C     . PHE A 1 306 ? 142.393 131.743 195.169 1.00 104.11 ? 306 PHE A C     1 
ATOM   2210 O O     . PHE A 1 306 ? 142.019 130.617 195.512 1.00 104.11 ? 306 PHE A O     1 
ATOM   2211 C CB    . PHE A 1 306 ? 141.415 131.920 192.861 1.00 104.11 ? 306 PHE A CB    1 
ATOM   2212 C CG    . PHE A 1 306 ? 140.348 132.910 193.236 1.00 104.11 ? 306 PHE A CG    1 
ATOM   2213 C CD1   . PHE A 1 306 ? 140.682 134.162 193.724 1.00 104.11 ? 306 PHE A CD1   1 
ATOM   2214 C CD2   . PHE A 1 306 ? 139.008 132.581 193.113 1.00 104.11 ? 306 PHE A CD2   1 
ATOM   2215 C CE1   . PHE A 1 306 ? 139.700 135.067 194.077 1.00 104.11 ? 306 PHE A CE1   1 
ATOM   2216 C CE2   . PHE A 1 306 ? 138.022 133.482 193.463 1.00 104.11 ? 306 PHE A CE2   1 
ATOM   2217 C CZ    . PHE A 1 306 ? 138.369 134.727 193.946 1.00 104.11 ? 306 PHE A CZ    1 
ATOM   2218 N N     . THR A 1 307 ? 142.565 132.750 196.024 1.00 104.63 ? 307 THR A N     1 
ATOM   2219 C CA    . THR A 1 307 ? 142.308 132.610 197.452 1.00 104.63 ? 307 THR A CA    1 
ATOM   2220 C C     . THR A 1 307 ? 140.927 133.171 197.774 1.00 104.63 ? 307 THR A C     1 
ATOM   2221 O O     . THR A 1 307 ? 140.649 134.344 197.499 1.00 104.63 ? 307 THR A O     1 
ATOM   2222 C CB    . THR A 1 307 ? 143.377 133.330 198.273 1.00 104.63 ? 307 THR A CB    1 
ATOM   2223 O OG1   . THR A 1 307 ? 143.354 134.730 197.965 1.00 104.63 ? 307 THR A OG1   1 
ATOM   2224 C CG2   . THR A 1 307 ? 144.758 132.773 197.967 1.00 104.63 ? 307 THR A CG2   1 
ATOM   2225 N N     . VAL A 1 308 ? 140.072 132.341 198.363 1.00 108.35 ? 308 VAL A N     1 
ATOM   2226 C CA    . VAL A 1 308 ? 138.706 132.719 198.709 1.00 108.35 ? 308 VAL A CA    1 
ATOM   2227 C C     . VAL A 1 308 ? 138.586 132.740 200.226 1.00 108.35 ? 308 VAL A C     1 
ATOM   2228 O O     . VAL A 1 308 ? 138.906 131.750 200.896 1.00 108.35 ? 308 VAL A O     1 
ATOM   2229 C CB    . VAL A 1 308 ? 137.679 131.764 198.085 1.00 108.35 ? 308 VAL A CB    1 
ATOM   2230 C CG1   . VAL A 1 308 ? 136.268 132.209 198.428 1.00 108.35 ? 308 VAL A CG1   1 
ATOM   2231 C CG2   . VAL A 1 308 ? 137.868 131.703 196.579 1.00 108.35 ? 308 VAL A CG2   1 
ATOM   2232 N N     . GLU A 1 309 ? 138.123 133.866 200.767 1.00 109.97 ? 309 GLU A N     1 
ATOM   2233 C CA    . GLU A 1 309 ? 137.976 134.037 202.212 1.00 109.97 ? 309 GLU A CA    1 
ATOM   2234 C C     . GLU A 1 309 ? 136.588 133.554 202.611 1.00 109.97 ? 309 GLU A C     1 
ATOM   2235 O O     . GLU A 1 309 ? 135.635 134.329 202.696 1.00 109.97 ? 309 GLU A O     1 
ATOM   2236 C CB    . GLU A 1 309 ? 138.202 135.490 202.608 1.00 109.97 ? 309 GLU A CB    1 
ATOM   2237 C CG    . GLU A 1 309 ? 139.637 135.960 202.442 1.00 109.97 ? 309 GLU A CG    1 
ATOM   2238 C CD    . GLU A 1 309 ? 140.065 136.926 203.528 1.00 109.97 ? 309 GLU A CD    1 
ATOM   2239 O OE1   . GLU A 1 309 ? 139.418 136.948 204.596 1.00 109.97 ? 309 GLU A OE1   1 
ATOM   2240 O OE2   . GLU A 1 309 ? 141.046 137.667 203.310 1.00 109.97 ? 309 GLU A OE2   1 
ATOM   2241 N N     . ARG A 1 310 ? 136.473 132.254 202.863 1.00 109.31 ? 310 ARG A N     1 
ATOM   2242 C CA    . ARG A 1 310 ? 135.206 131.661 203.259 1.00 109.31 ? 310 ARG A CA    1 
ATOM   2243 C C     . ARG A 1 310 ? 135.008 131.773 204.769 1.00 109.31 ? 310 ARG A C     1 
ATOM   2244 O O     . ARG A 1 310 ? 135.940 132.040 205.531 1.00 109.31 ? 310 ARG A O     1 
ATOM   2245 C CB    . ARG A 1 310 ? 135.137 130.198 202.819 1.00 109.31 ? 310 ARG A CB    1 
ATOM   2246 C CG    . ARG A 1 310 ? 135.391 129.984 201.337 1.00 109.31 ? 310 ARG A CG    1 
ATOM   2247 C CD    . ARG A 1 310 ? 135.133 128.541 200.934 1.00 109.31 ? 310 ARG A CD    1 
ATOM   2248 N NE    . ARG A 1 310 ? 135.902 127.599 201.737 1.00 109.31 ? 310 ARG A NE    1 
ATOM   2249 C CZ    . ARG A 1 310 ? 136.235 126.377 201.344 1.00 109.31 ? 310 ARG A CZ    1 
ATOM   2250 N NH1   . ARG A 1 310 ? 135.887 125.914 200.154 1.00 109.31 ? 310 ARG A NH1   1 
ATOM   2251 N NH2   . ARG A 1 310 ? 136.934 125.599 202.165 1.00 109.31 ? 310 ARG A NH2   1 
ATOM   2252 N N     . SER A 1 311 ? 133.767 131.562 205.198 1.00 106.58 ? 311 SER A N     1 
ATOM   2253 C CA    . SER A 1 311 ? 133.439 131.620 206.612 1.00 106.58 ? 311 SER A CA    1 
ATOM   2254 C C     . SER A 1 311 ? 133.989 130.397 207.341 1.00 106.58 ? 311 SER A C     1 
ATOM   2255 O O     . SER A 1 311 ? 134.326 129.376 206.736 1.00 106.58 ? 311 SER A O     1 
ATOM   2256 C CB    . SER A 1 311 ? 131.926 131.712 206.812 1.00 106.58 ? 311 SER A CB    1 
ATOM   2257 O OG    . SER A 1 311 ? 131.281 130.523 206.389 1.00 106.58 ? 311 SER A OG    1 
ATOM   2258 N N     . ALA A 1 312 ? 134.075 130.514 208.668 1.00 107.43 ? 312 ALA A N     1 
ATOM   2259 C CA    . ALA A 1 312 ? 134.575 129.420 209.490 1.00 107.43 ? 312 ALA A CA    1 
ATOM   2260 C C     . ALA A 1 312 ? 133.633 128.224 209.521 1.00 107.43 ? 312 ALA A C     1 
ATOM   2261 O O     . ALA A 1 312 ? 134.055 127.137 209.928 1.00 107.43 ? 312 ALA A O     1 
ATOM   2262 C CB    . ALA A 1 312 ? 134.834 129.909 210.916 1.00 107.43 ? 312 ALA A CB    1 
ATOM   2263 N N     . ASP A 1 313 ? 132.380 128.394 209.105 1.00 111.40 ? 313 ASP A N     1 
ATOM   2264 C CA    . ASP A 1 313 ? 131.410 127.308 209.078 1.00 111.40 ? 313 ASP A CA    1 
ATOM   2265 C C     . ASP A 1 313 ? 131.366 126.587 207.738 1.00 111.40 ? 313 ASP A C     1 
ATOM   2266 O O     . ASP A 1 313 ? 130.567 125.658 207.577 1.00 111.40 ? 313 ASP A O     1 
ATOM   2267 C CB    . ASP A 1 313 ? 130.015 127.840 209.421 1.00 111.40 ? 313 ASP A CB    1 
ATOM   2268 C CG    . ASP A 1 313 ? 129.899 128.282 210.867 1.00 111.40 ? 313 ASP A CG    1 
ATOM   2269 O OD1   . ASP A 1 313 ? 130.942 128.590 211.482 1.00 111.40 ? 313 ASP A OD1   1 
ATOM   2270 O OD2   . ASP A 1 313 ? 128.766 128.321 211.389 1.00 111.40 ? 313 ASP A OD2   1 
ATOM   2271 N N     . ASN A 1 314 ? 132.197 126.990 206.776 1.00 113.64 ? 314 ASN A N     1 
ATOM   2272 C CA    . ASN A 1 314 ? 132.240 126.356 205.466 1.00 113.64 ? 314 ASN A CA    1 
ATOM   2273 C C     . ASN A 1 314 ? 133.513 125.559 205.222 1.00 113.64 ? 314 ASN A C     1 
ATOM   2274 O O     . ASN A 1 314 ? 133.580 124.822 204.232 1.00 113.64 ? 314 ASN A O     1 
ATOM   2275 C CB    . ASN A 1 314 ? 132.085 127.410 204.359 1.00 113.64 ? 314 ASN A CB    1 
ATOM   2276 C CG    . ASN A 1 314 ? 130.653 127.882 204.198 1.00 113.64 ? 314 ASN A CG    1 
ATOM   2277 O OD1   . ASN A 1 314 ? 129.736 127.343 204.818 1.00 113.64 ? 314 ASN A OD1   1 
ATOM   2278 N ND2   . ASN A 1 314 ? 130.454 128.893 203.361 1.00 113.64 ? 314 ASN A ND2   1 
ATOM   2279 N N     . GLY A 1 315 ? 134.515 125.683 206.088 1.00 110.78 ? 315 GLY A N     1 
ATOM   2280 C CA    . GLY A 1 315 ? 135.760 124.961 205.915 1.00 110.78 ? 315 GLY A CA    1 
ATOM   2281 C C     . GLY A 1 315 ? 136.977 125.857 206.003 1.00 110.78 ? 315 GLY A C     1 
ATOM   2282 O O     . GLY A 1 315 ? 138.095 125.431 205.698 1.00 110.78 ? 315 GLY A O     1 
ATOM   2283 N N     . GLY A 1 316 ? 136.772 127.102 206.420 1.00 109.12 ? 316 GLY A N     1 
ATOM   2284 C CA    . GLY A 1 316 ? 137.861 128.044 206.541 1.00 109.12 ? 316 GLY A CA    1 
ATOM   2285 C C     . GLY A 1 316 ? 138.343 128.552 205.195 1.00 109.12 ? 316 GLY A C     1 
ATOM   2286 O O     . GLY A 1 316 ? 137.720 128.350 204.148 1.00 109.12 ? 316 GLY A O     1 
ATOM   2287 N N     . ASN A 1 317 ? 139.484 129.233 205.238 1.00 107.11 ? 317 ASN A N     1 
ATOM   2288 C CA    . ASN A 1 317 ? 140.086 129.759 204.022 1.00 107.11 ? 317 ASN A CA    1 
ATOM   2289 C C     . ASN A 1 317 ? 140.655 128.623 203.179 1.00 107.11 ? 317 ASN A C     1 
ATOM   2290 O O     . ASN A 1 317 ? 141.341 127.733 203.689 1.00 107.11 ? 317 ASN A O     1 
ATOM   2291 C CB    . ASN A 1 317 ? 141.188 130.762 204.365 1.00 107.11 ? 317 ASN A CB    1 
ATOM   2292 C CG    . ASN A 1 317 ? 140.649 132.025 205.011 1.00 107.11 ? 317 ASN A CG    1 
ATOM   2293 O OD1   . ASN A 1 317 ? 139.619 132.558 204.600 1.00 107.11 ? 317 ASN A OD1   1 
ATOM   2294 N ND2   . ASN A 1 317 ? 141.348 132.511 206.030 1.00 107.11 ? 317 ASN A ND2   1 
ATOM   2295 N N     . LYS A 1 318 ? 140.366 128.657 201.880 1.00 109.22 ? 318 LYS A N     1 
ATOM   2296 C CA    . LYS A 1 318 ? 140.839 127.647 200.945 1.00 109.22 ? 318 LYS A CA    1 
ATOM   2297 C C     . LYS A 1 318 ? 141.304 128.313 199.658 1.00 109.22 ? 318 LYS A C     1 
ATOM   2298 O O     . LYS A 1 318 ? 140.682 129.268 199.184 1.00 109.22 ? 318 LYS A O     1 
ATOM   2299 C CB    . LYS A 1 318 ? 139.742 126.619 200.636 1.00 109.22 ? 318 LYS A CB    1 
ATOM   2300 C CG    . LYS A 1 318 ? 140.202 125.465 199.763 1.00 109.22 ? 318 LYS A CG    1 
ATOM   2301 C CD    . LYS A 1 318 ? 139.402 124.207 200.038 1.00 109.22 ? 318 LYS A CD    1 
ATOM   2302 C CE    . LYS A 1 318 ? 139.643 123.162 198.963 1.00 109.22 ? 318 LYS A CE    1 
ATOM   2303 N NZ    . LYS A 1 318 ? 138.581 122.120 198.969 1.00 109.22 ? 318 LYS A NZ    1 
ATOM   2304 N N     . THR A 1 319 ? 142.399 127.804 199.097 1.00 105.04 ? 319 THR A N     1 
ATOM   2305 C CA    . THR A 1 319 ? 142.943 128.296 197.838 1.00 105.04 ? 319 THR A CA    1 
ATOM   2306 C C     . THR A 1 319 ? 142.703 127.258 196.748 1.00 105.04 ? 319 THR A C     1 
ATOM   2307 O O     . THR A 1 319 ? 143.032 126.080 196.924 1.00 105.04 ? 319 THR A O     1 
ATOM   2308 C CB    . THR A 1 319 ? 144.440 128.593 197.963 1.00 105.04 ? 319 THR A CB    1 
ATOM   2309 O OG1   . THR A 1 319 ? 144.651 129.612 198.947 1.00 105.04 ? 319 THR A OG1   1 
ATOM   2310 C CG2   . THR A 1 319 ? 144.998 129.075 196.634 1.00 105.04 ? 319 THR A CG2   1 
ATOM   2311 N N     . PHE A 1 320 ? 142.139 127.696 195.627 1.00 106.66 ? 320 PHE A N     1 
ATOM   2312 C CA    . PHE A 1 320 ? 141.828 126.816 194.507 1.00 106.66 ? 320 PHE A CA    1 
ATOM   2313 C C     . PHE A 1 320 ? 142.894 126.974 193.430 1.00 106.66 ? 320 PHE A C     1 
ATOM   2314 O O     . PHE A 1 320 ? 143.191 128.095 193.004 1.00 106.66 ? 320 PHE A O     1 
ATOM   2315 C CB    . PHE A 1 320 ? 140.441 127.119 193.942 1.00 106.66 ? 320 PHE A CB    1 
ATOM   2316 C CG    . PHE A 1 320 ? 139.346 127.077 194.968 1.00 106.66 ? 320 PHE A CG    1 
ATOM   2317 C CD1   . PHE A 1 320 ? 138.818 125.867 195.383 1.00 106.66 ? 320 PHE A CD1   1 
ATOM   2318 C CD2   . PHE A 1 320 ? 138.843 128.244 195.517 1.00 106.66 ? 320 PHE A CD2   1 
ATOM   2319 C CE1   . PHE A 1 320 ? 137.809 125.820 196.324 1.00 106.66 ? 320 PHE A CE1   1 
ATOM   2320 C CE2   . PHE A 1 320 ? 137.832 128.202 196.461 1.00 106.66 ? 320 PHE A CE2   1 
ATOM   2321 C CZ    . PHE A 1 320 ? 137.315 126.987 196.864 1.00 106.66 ? 320 PHE A CZ    1 
ATOM   2322 N N     . LYS A 1 321 ? 143.466 125.852 192.997 1.00 108.94 ? 321 LYS A N     1 
ATOM   2323 C CA    . LYS A 1 321 ? 144.555 125.853 192.031 1.00 108.94 ? 321 LYS A CA    1 
ATOM   2324 C C     . LYS A 1 321 ? 144.071 125.697 190.592 1.00 108.94 ? 321 LYS A C     1 
ATOM   2325 O O     . LYS A 1 321 ? 144.820 126.018 189.664 1.00 108.94 ? 321 LYS A O     1 
ATOM   2326 C CB    . LYS A 1 321 ? 145.540 124.727 192.388 1.00 108.94 ? 321 LYS A CB    1 
ATOM   2327 C CG    . LYS A 1 321 ? 146.778 124.602 191.515 1.00 108.94 ? 321 LYS A CG    1 
ATOM   2328 C CD    . LYS A 1 321 ? 147.649 125.840 191.632 1.00 108.94 ? 321 LYS A CD    1 
ATOM   2329 C CE    . LYS A 1 321 ? 148.296 125.930 193.003 1.00 108.94 ? 321 LYS A CE    1 
ATOM   2330 N NZ    . LYS A 1 321 ? 149.198 127.110 193.099 1.00 108.94 ? 321 LYS A NZ    1 
ATOM   2331 N N     . SER A 1 322 ? 142.834 125.251 190.380 1.00 107.14 ? 322 SER A N     1 
ATOM   2332 C CA    . SER A 1 322 ? 142.329 125.020 189.035 1.00 107.14 ? 322 SER A CA    1 
ATOM   2333 C C     . SER A 1 322 ? 140.851 125.368 188.954 1.00 107.14 ? 322 SER A C     1 
ATOM   2334 O O     . SER A 1 322 ? 140.109 125.224 189.933 1.00 107.14 ? 322 SER A O     1 
ATOM   2335 C CB    . SER A 1 322 ? 142.539 123.565 188.600 1.00 107.14 ? 322 SER A CB    1 
ATOM   2336 O OG    . SER A 1 322 ? 141.514 122.728 189.107 1.00 107.14 ? 322 SER A OG    1 
ATOM   2337 N N     . TYR A 1 323 ? 140.430 125.822 187.771 1.00 105.40 ? 323 TYR A N     1 
ATOM   2338 C CA    . TYR A 1 323 ? 139.020 126.119 187.553 1.00 105.40 ? 323 TYR A CA    1 
ATOM   2339 C C     . TYR A 1 323 ? 138.152 124.890 187.770 1.00 105.40 ? 323 TYR A C     1 
ATOM   2340 O O     . TYR A 1 323 ? 137.020 125.012 188.246 1.00 105.40 ? 323 TYR A O     1 
ATOM   2341 C CB    . TYR A 1 323 ? 138.806 126.679 186.146 1.00 105.40 ? 323 TYR A CB    1 
ATOM   2342 C CG    . TYR A 1 323 ? 137.350 126.831 185.764 1.00 105.40 ? 323 TYR A CG    1 
ATOM   2343 C CD1   . TYR A 1 323 ? 136.590 127.892 186.241 1.00 105.40 ? 323 TYR A CD1   1 
ATOM   2344 C CD2   . TYR A 1 323 ? 136.736 125.917 184.919 1.00 105.40 ? 323 TYR A CD2   1 
ATOM   2345 C CE1   . TYR A 1 323 ? 135.257 128.032 185.892 1.00 105.40 ? 323 TYR A CE1   1 
ATOM   2346 C CE2   . TYR A 1 323 ? 135.406 126.049 184.564 1.00 105.40 ? 323 TYR A CE2   1 
ATOM   2347 C CZ    . TYR A 1 323 ? 134.672 127.107 185.052 1.00 105.40 ? 323 TYR A CZ    1 
ATOM   2348 O OH    . TYR A 1 323 ? 133.348 127.240 184.699 1.00 105.40 ? 323 TYR A OH    1 
ATOM   2349 N N     . GLU A 1 324 ? 138.663 123.702 187.439 1.00 110.97 ? 324 GLU A N     1 
ATOM   2350 C CA    . GLU A 1 324 ? 137.878 122.482 187.602 1.00 110.97 ? 324 GLU A CA    1 
ATOM   2351 C C     . GLU A 1 324 ? 137.534 122.237 189.067 1.00 110.97 ? 324 GLU A C     1 
ATOM   2352 O O     . GLU A 1 324 ? 136.366 122.024 189.415 1.00 110.97 ? 324 GLU A O     1 
ATOM   2353 C CB    . GLU A 1 324 ? 138.636 121.290 187.013 1.00 110.97 ? 324 GLU A CB    1 
ATOM   2354 C CG    . GLU A 1 324 ? 138.391 121.004 185.519 1.00 110.97 ? 324 GLU A CG    1 
ATOM   2355 C CD    . GLU A 1 324 ? 136.923 120.817 185.124 1.00 110.97 ? 324 GLU A CD    1 
ATOM   2356 O OE1   . GLU A 1 324 ? 136.671 120.595 183.921 1.00 110.97 ? 324 GLU A OE1   1 
ATOM   2357 O OE2   . GLU A 1 324 ? 136.027 120.828 185.995 1.00 110.97 ? 324 GLU A OE2   1 
ATOM   2358 N N     . GLU A 1 325 ? 138.537 122.278 189.948 1.00 111.63 ? 325 GLU A N     1 
ATOM   2359 C CA    . GLU A 1 325 ? 138.252 122.069 191.364 1.00 111.63 ? 325 GLU A CA    1 
ATOM   2360 C C     . GLU A 1 325 ? 137.470 123.235 191.953 1.00 111.63 ? 325 GLU A C     1 
ATOM   2361 O O     . GLU A 1 325 ? 136.642 123.030 192.848 1.00 111.63 ? 325 GLU A O     1 
ATOM   2362 C CB    . GLU A 1 325 ? 139.543 121.837 192.153 1.00 111.63 ? 325 GLU A CB    1 
ATOM   2363 C CG    . GLU A 1 325 ? 140.488 123.022 192.210 1.00 111.63 ? 325 GLU A CG    1 
ATOM   2364 C CD    . GLU A 1 325 ? 141.768 122.700 192.951 1.00 111.63 ? 325 GLU A CD    1 
ATOM   2365 O OE1   . GLU A 1 325 ? 141.921 121.544 193.397 1.00 111.63 ? 325 GLU A OE1   1 
ATOM   2366 O OE2   . GLU A 1 325 ? 142.614 123.603 193.101 1.00 111.63 ? 325 GLU A OE2   1 
ATOM   2367 N N     . LEU A 1 326 ? 137.703 124.456 191.461 1.00 105.59 ? 326 LEU A N     1 
ATOM   2368 C CA    . LEU A 1 326 ? 136.939 125.597 191.955 1.00 105.59 ? 326 LEU A CA    1 
ATOM   2369 C C     . LEU A 1 326 ? 135.455 125.431 191.645 1.00 105.59 ? 326 LEU A C     1 
ATOM   2370 O O     . LEU A 1 326 ? 134.601 125.610 192.522 1.00 105.59 ? 326 LEU A O     1 
ATOM   2371 C CB    . LEU A 1 326 ? 137.491 126.894 191.355 1.00 105.59 ? 326 LEU A CB    1 
ATOM   2372 C CG    . LEU A 1 326 ? 136.964 128.243 191.863 1.00 105.59 ? 326 LEU A CG    1 
ATOM   2373 C CD1   . LEU A 1 326 ? 138.020 129.320 191.674 1.00 105.59 ? 326 LEU A CD1   1 
ATOM   2374 C CD2   . LEU A 1 326 ? 135.676 128.658 191.163 1.00 105.59 ? 326 LEU A CD2   1 
ATOM   2375 N N     . ILE A 1 327 ? 135.128 125.067 190.403 1.00 103.73 ? 327 ILE A N     1 
ATOM   2376 C CA    . ILE A 1 327 ? 133.728 124.893 190.030 1.00 103.73 ? 327 ILE A CA    1 
ATOM   2377 C C     . ILE A 1 327 ? 133.139 123.657 190.699 1.00 103.73 ? 327 ILE A C     1 
ATOM   2378 O O     . ILE A 1 327 ? 131.947 123.634 191.023 1.00 103.73 ? 327 ILE A O     1 
ATOM   2379 C CB    . ILE A 1 327 ? 133.570 124.853 188.496 1.00 103.73 ? 327 ILE A CB    1 
ATOM   2380 C CG1   . ILE A 1 327 ? 132.110 125.085 188.104 1.00 103.73 ? 327 ILE A CG1   1 
ATOM   2381 C CG2   . ILE A 1 327 ? 134.060 123.535 187.919 1.00 103.73 ? 327 ILE A CG2   1 
ATOM   2382 C CD1   . ILE A 1 327 ? 131.669 126.524 188.227 1.00 103.73 ? 327 ILE A CD1   1 
ATOM   2383 N N     . ALA A 1 328 ? 133.949 122.621 190.938 1.00 107.84 ? 328 ALA A N     1 
ATOM   2384 C CA    . ALA A 1 328 ? 133.451 121.449 191.651 1.00 107.84 ? 328 ALA A CA    1 
ATOM   2385 C C     . ALA A 1 328 ? 133.067 121.802 193.083 1.00 107.84 ? 328 ALA A C     1 
ATOM   2386 O O     . ALA A 1 328 ? 132.004 121.398 193.573 1.00 107.84 ? 328 ALA A O     1 
ATOM   2387 C CB    . ALA A 1 328 ? 134.500 120.337 191.630 1.00 107.84 ? 328 ALA A CB    1 
ATOM   2388 N N     . ASP A 1 329 ? 133.919 122.567 193.770 1.00 110.17 ? 329 ASP A N     1 
ATOM   2389 C CA    . ASP A 1 329 ? 133.605 122.978 195.134 1.00 110.17 ? 329 ASP A CA    1 
ATOM   2390 C C     . ASP A 1 329 ? 132.444 123.963 195.168 1.00 110.17 ? 329 ASP A C     1 
ATOM   2391 O O     . ASP A 1 329 ? 131.663 123.966 196.126 1.00 110.17 ? 329 ASP A O     1 
ATOM   2392 C CB    . ASP A 1 329 ? 134.842 123.582 195.798 1.00 110.17 ? 329 ASP A CB    1 
ATOM   2393 C CG    . ASP A 1 329 ? 135.851 122.528 196.213 1.00 110.17 ? 329 ASP A CG    1 
ATOM   2394 O OD1   . ASP A 1 329 ? 135.442 121.373 196.453 1.00 110.17 ? 329 ASP A OD1   1 
ATOM   2395 O OD2   . ASP A 1 329 ? 137.054 122.851 196.295 1.00 110.17 ? 329 ASP A OD2   1 
ATOM   2396 N N     . TYR A 1 330 ? 132.319 124.806 194.141 1.00 105.24 ? 330 TYR A N     1 
ATOM   2397 C CA    . TYR A 1 330 ? 131.171 125.702 194.050 1.00 105.24 ? 330 TYR A CA    1 
ATOM   2398 C C     . TYR A 1 330 ? 129.874 124.921 193.863 1.00 105.24 ? 330 TYR A C     1 
ATOM   2399 O O     . TYR A 1 330 ? 128.847 125.257 194.464 1.00 105.24 ? 330 TYR A O     1 
ATOM   2400 C CB    . TYR A 1 330 ? 131.385 126.692 192.906 1.00 105.24 ? 330 TYR A CB    1 
ATOM   2401 C CG    . TYR A 1 330 ? 130.126 127.325 192.365 1.00 105.24 ? 330 TYR A CG    1 
ATOM   2402 C CD1   . TYR A 1 330 ? 129.481 128.338 193.060 1.00 105.24 ? 330 TYR A CD1   1 
ATOM   2403 C CD2   . TYR A 1 330 ? 129.591 126.919 191.151 1.00 105.24 ? 330 TYR A CD2   1 
ATOM   2404 C CE1   . TYR A 1 330 ? 128.333 128.924 192.564 1.00 105.24 ? 330 TYR A CE1   1 
ATOM   2405 C CE2   . TYR A 1 330 ? 128.445 127.496 190.649 1.00 105.24 ? 330 TYR A CE2   1 
ATOM   2406 C CZ    . TYR A 1 330 ? 127.822 128.500 191.356 1.00 105.24 ? 330 TYR A CZ    1 
ATOM   2407 O OH    . TYR A 1 330 ? 126.678 129.077 190.856 1.00 105.24 ? 330 TYR A OH    1 
ATOM   2408 N N     . GLU A 1 331 ? 129.903 123.879 193.028 1.00 105.41 ? 331 GLU A N     1 
ATOM   2409 C CA    . GLU A 1 331 ? 128.730 123.031 192.841 1.00 105.41 ? 331 GLU A CA    1 
ATOM   2410 C C     . GLU A 1 331 ? 128.382 122.272 194.115 1.00 105.41 ? 331 GLU A C     1 
ATOM   2411 O O     . GLU A 1 331 ? 127.202 122.137 194.460 1.00 105.41 ? 331 GLU A O     1 
ATOM   2412 C CB    . GLU A 1 331 ? 128.970 122.050 191.694 1.00 105.41 ? 331 GLU A CB    1 
ATOM   2413 C CG    . GLU A 1 331 ? 128.766 122.627 190.307 1.00 105.41 ? 331 GLU A CG    1 
ATOM   2414 C CD    . GLU A 1 331 ? 129.167 121.652 189.218 1.00 105.41 ? 331 GLU A CD    1 
ATOM   2415 O OE1   . GLU A 1 331 ? 130.325 121.184 189.237 1.00 105.41 ? 331 GLU A OE1   1 
ATOM   2416 O OE2   . GLU A 1 331 ? 128.323 121.340 188.353 1.00 105.41 ? 331 GLU A OE2   1 
ATOM   2417 N N     . SER A 1 332 ? 129.393 121.763 194.823 1.00 109.90 ? 332 SER A N     1 
ATOM   2418 C CA    . SER A 1 332 ? 129.151 120.931 195.997 1.00 109.90 ? 332 SER A CA    1 
ATOM   2419 C C     . SER A 1 332 ? 128.462 121.680 197.131 1.00 109.90 ? 332 SER A C     1 
ATOM   2420 O O     . SER A 1 332 ? 127.903 121.033 198.023 1.00 109.90 ? 332 SER A O     1 
ATOM   2421 C CB    . SER A 1 332 ? 130.468 120.329 196.488 1.00 109.90 ? 332 SER A CB    1 
ATOM   2422 O OG    . SER A 1 332 ? 131.380 121.343 196.861 1.00 109.90 ? 332 SER A OG    1 
ATOM   2423 N N     . GLY A 1 333 ? 128.484 123.010 197.124 1.00 112.17 ? 333 GLY A N     1 
ATOM   2424 C CA    . GLY A 1 333 ? 127.666 123.780 198.038 1.00 112.17 ? 333 GLY A CA    1 
ATOM   2425 C C     . GLY A 1 333 ? 128.360 124.377 199.240 1.00 112.17 ? 333 GLY A C     1 
ATOM   2426 O O     . GLY A 1 333 ? 127.686 124.986 200.078 1.00 112.17 ? 333 GLY A O     1 
ATOM   2427 N N     . GLU A 1 334 ? 129.678 124.229 199.365 1.00 116.39 ? 334 GLU A N     1 
ATOM   2428 C CA    . GLU A 1 334 ? 130.410 124.895 200.434 1.00 116.39 ? 334 GLU A CA    1 
ATOM   2429 C C     . GLU A 1 334 ? 130.983 126.237 200.002 1.00 116.39 ? 334 GLU A C     1 
ATOM   2430 O O     . GLU A 1 334 ? 131.600 126.926 200.821 1.00 116.39 ? 334 GLU A O     1 
ATOM   2431 C CB    . GLU A 1 334 ? 131.534 124.000 200.967 1.00 116.39 ? 334 GLU A CB    1 
ATOM   2432 C CG    . GLU A 1 334 ? 132.755 123.914 200.072 1.00 116.39 ? 334 GLU A CG    1 
ATOM   2433 C CD    . GLU A 1 334 ? 132.679 122.756 199.105 1.00 116.39 ? 334 GLU A CD    1 
ATOM   2434 O OE1   . GLU A 1 334 ? 131.564 122.238 198.888 1.00 116.39 ? 334 GLU A OE1   1 
ATOM   2435 O OE2   . GLU A 1 334 ? 133.733 122.358 198.567 1.00 116.39 ? 334 GLU A OE2   1 
ATOM   2436 N N     . LEU A 1 335 ? 130.796 126.621 198.742 1.00 111.60 ? 335 LEU A N     1 
ATOM   2437 C CA    . LEU A 1 335 ? 131.196 127.930 198.243 1.00 111.60 ? 335 LEU A CA    1 
ATOM   2438 C C     . LEU A 1 335 ? 129.940 128.673 197.811 1.00 111.60 ? 335 LEU A C     1 
ATOM   2439 O O     . LEU A 1 335 ? 129.166 128.166 196.992 1.00 111.60 ? 335 LEU A O     1 
ATOM   2440 C CB    . LEU A 1 335 ? 132.184 127.804 197.081 1.00 111.60 ? 335 LEU A CB    1 
ATOM   2441 C CG    . LEU A 1 335 ? 132.449 129.068 196.261 1.00 111.60 ? 335 LEU A CG    1 
ATOM   2442 C CD1   . LEU A 1 335 ? 133.013 130.173 197.141 1.00 111.60 ? 335 LEU A CD1   1 
ATOM   2443 C CD2   . LEU A 1 335 ? 133.393 128.769 195.109 1.00 111.60 ? 335 LEU A CD2   1 
ATOM   2444 N N     . HIS A 1 336 ? 129.744 129.864 198.358 1.00 114.75 ? 336 HIS A N     1 
ATOM   2445 C CA    . HIS A 1 336 ? 128.562 130.674 198.122 1.00 114.75 ? 336 HIS A CA    1 
ATOM   2446 C C     . HIS A 1 336 ? 128.955 132.007 197.501 1.00 114.75 ? 336 HIS A C     1 
ATOM   2447 O O     . HIS A 1 336 ? 130.107 132.442 197.622 1.00 114.75 ? 336 HIS A O     1 
ATOM   2448 C CB    . HIS A 1 336 ? 127.799 130.918 199.433 1.00 114.75 ? 336 HIS A CB    1 
ATOM   2449 C CG    . HIS A 1 336 ? 127.334 129.663 200.103 1.00 114.75 ? 336 HIS A CG    1 
ATOM   2450 N ND1   . HIS A 1 336 ? 126.568 128.715 199.458 1.00 114.75 ? 336 HIS A ND1   1 
ATOM   2451 C CD2   . HIS A 1 336 ? 127.525 129.199 201.361 1.00 114.75 ? 336 HIS A CD2   1 
ATOM   2452 C CE1   . HIS A 1 336 ? 126.308 127.723 200.290 1.00 114.75 ? 336 HIS A CE1   1 
ATOM   2453 N NE2   . HIS A 1 336 ? 126.877 127.992 201.451 1.00 114.75 ? 336 HIS A NE2   1 
ATOM   2454 N N     . PRO A 1 337 ? 128.028 132.672 196.806 1.00 105.84 ? 337 PRO A N     1 
ATOM   2455 C CA    . PRO A 1 337 ? 128.340 134.010 196.278 1.00 105.84 ? 337 PRO A CA    1 
ATOM   2456 C C     . PRO A 1 337 ? 128.737 135.003 197.355 1.00 105.84 ? 337 PRO A C     1 
ATOM   2457 O O     . PRO A 1 337 ? 129.577 135.874 197.097 1.00 105.84 ? 337 PRO A O     1 
ATOM   2458 C CB    . PRO A 1 337 ? 127.036 134.422 195.581 1.00 105.84 ? 337 PRO A CB    1 
ATOM   2459 C CG    . PRO A 1 337 ? 126.376 133.134 195.230 1.00 105.84 ? 337 PRO A CG    1 
ATOM   2460 C CD    . PRO A 1 337 ? 126.717 132.186 196.343 1.00 105.84 ? 337 PRO A CD    1 
ATOM   2461 N N     . ALA A 1 338 ? 128.175 134.885 198.561 1.00 104.81 ? 338 ALA A N     1 
ATOM   2462 C CA    . ALA A 1 338 ? 128.509 135.807 199.642 1.00 104.81 ? 338 ALA A CA    1 
ATOM   2463 C C     . ALA A 1 338 ? 129.978 135.731 200.040 1.00 104.81 ? 338 ALA A C     1 
ATOM   2464 O O     . ALA A 1 338 ? 130.493 136.677 200.645 1.00 104.81 ? 338 ALA A O     1 
ATOM   2465 C CB    . ALA A 1 338 ? 127.625 135.532 200.859 1.00 104.81 ? 338 ALA A CB    1 
ATOM   2466 N N     . ASP A 1 339 ? 130.657 134.628 199.730 1.00 105.31 ? 339 ASP A N     1 
ATOM   2467 C CA    . ASP A 1 339 ? 132.094 134.517 199.943 1.00 105.31 ? 339 ASP A CA    1 
ATOM   2468 C C     . ASP A 1 339 ? 132.894 134.656 198.658 1.00 105.31 ? 339 ASP A C     1 
ATOM   2469 O O     . ASP A 1 339 ? 134.065 135.046 198.707 1.00 105.31 ? 339 ASP A O     1 
ATOM   2470 C CB    . ASP A 1 339 ? 132.434 133.176 200.601 1.00 105.31 ? 339 ASP A CB    1 
ATOM   2471 C CG    . ASP A 1 339 ? 131.787 133.014 201.962 1.00 105.31 ? 339 ASP A CG    1 
ATOM   2472 O OD1   . ASP A 1 339 ? 131.234 134.006 202.481 1.00 105.31 ? 339 ASP A OD1   1 
ATOM   2473 O OD2   . ASP A 1 339 ? 131.833 131.894 202.513 1.00 105.31 ? 339 ASP A OD2   1 
ATOM   2474 N N     . LEU A 1 340 ? 132.286 134.343 197.512 1.00 102.91 ? 340 LEU A N     1 
ATOM   2475 C CA    . LEU A 1 340 ? 132.985 134.459 196.237 1.00 102.91 ? 340 LEU A CA    1 
ATOM   2476 C C     . LEU A 1 340 ? 133.165 135.919 195.838 1.00 102.91 ? 340 LEU A C     1 
ATOM   2477 O O     . LEU A 1 340 ? 134.239 136.317 195.373 1.00 102.91 ? 340 LEU A O     1 
ATOM   2478 C CB    . LEU A 1 340 ? 132.220 133.688 195.159 1.00 102.91 ? 340 LEU A CB    1 
ATOM   2479 C CG    . LEU A 1 340 ? 132.834 133.576 193.763 1.00 102.91 ? 340 LEU A CG    1 
ATOM   2480 C CD1   . LEU A 1 340 ? 132.598 132.184 193.204 1.00 102.91 ? 340 LEU A CD1   1 
ATOM   2481 C CD2   . LEU A 1 340 ? 132.251 134.628 192.831 1.00 102.91 ? 340 LEU A CD2   1 
ATOM   2482 N N     . LYS A 1 341 ? 132.119 136.729 196.006 1.00 100.96 ? 341 LYS A N     1 
ATOM   2483 C CA    . LYS A 1 341 ? 132.195 138.135 195.614 1.00 100.96 ? 341 LYS A CA    1 
ATOM   2484 C C     . LYS A 1 341 ? 133.264 138.914 196.369 1.00 100.96 ? 341 LYS A C     1 
ATOM   2485 O O     . LYS A 1 341 ? 133.991 139.690 195.726 1.00 100.96 ? 341 LYS A O     1 
ATOM   2486 C CB    . LYS A 1 341 ? 130.815 138.785 195.763 1.00 100.96 ? 341 LYS A CB    1 
ATOM   2487 C CG    . LYS A 1 341 ? 129.808 138.335 194.719 1.00 100.96 ? 341 LYS A CG    1 
ATOM   2488 C CD    . LYS A 1 341 ? 128.521 139.134 194.812 1.00 100.96 ? 341 LYS A CD    1 
ATOM   2489 C CE    . LYS A 1 341 ? 127.561 138.760 193.695 1.00 100.96 ? 341 LYS A CE    1 
ATOM   2490 N NZ    . LYS A 1 341 ? 127.032 137.379 193.866 1.00 100.96 ? 341 LYS A NZ    1 
ATOM   2491 N N     . PRO A 1 342 ? 133.407 138.800 197.697 1.00 95.68  ? 342 PRO A N     1 
ATOM   2492 C CA    . PRO A 1 342 ? 134.518 139.515 198.353 1.00 95.68  ? 342 PRO A CA    1 
ATOM   2493 C C     . PRO A 1 342 ? 135.888 139.089 197.852 1.00 95.68  ? 342 PRO A C     1 
ATOM   2494 O O     . PRO A 1 342 ? 136.758 139.942 197.637 1.00 95.68  ? 342 PRO A O     1 
ATOM   2495 C CB    . PRO A 1 342 ? 134.324 139.179 199.838 1.00 95.68  ? 342 PRO A CB    1 
ATOM   2496 C CG    . PRO A 1 342 ? 132.887 138.835 199.966 1.00 95.68  ? 342 PRO A CG    1 
ATOM   2497 C CD    . PRO A 1 342 ? 132.522 138.156 198.685 1.00 95.68  ? 342 PRO A CD    1 
ATOM   2498 N N     . ALA A 1 343 ? 136.102 137.786 197.647 1.00 92.81  ? 343 ALA A N     1 
ATOM   2499 C CA    . ALA A 1 343 ? 137.388 137.316 197.141 1.00 92.81  ? 343 ALA A CA    1 
ATOM   2500 C C     . ALA A 1 343 ? 137.619 137.771 195.705 1.00 92.81  ? 343 ALA A C     1 
ATOM   2501 O O     . ALA A 1 343 ? 138.733 138.172 195.346 1.00 92.81  ? 343 ALA A O     1 
ATOM   2502 C CB    . ALA A 1 343 ? 137.466 135.795 197.243 1.00 92.81  ? 343 ALA A CB    1 
ATOM   2503 N N     . LEU A 1 344 ? 136.578 137.710 194.869 1.00 90.92  ? 344 LEU A N     1 
ATOM   2504 C CA    . LEU A 1 344 ? 136.690 138.210 193.503 1.00 90.92  ? 344 LEU A CA    1 
ATOM   2505 C C     . LEU A 1 344 ? 137.052 139.688 193.500 1.00 90.92  ? 344 LEU A C     1 
ATOM   2506 O O     . LEU A 1 344 ? 137.926 140.123 192.740 1.00 90.92  ? 344 LEU A O     1 
ATOM   2507 C CB    . LEU A 1 344 ? 135.374 137.975 192.756 1.00 90.92  ? 344 LEU A CB    1 
ATOM   2508 C CG    . LEU A 1 344 ? 135.292 138.134 191.233 1.00 90.92  ? 344 LEU A CG    1 
ATOM   2509 C CD1   . LEU A 1 344 ? 134.147 137.299 190.682 1.00 90.92  ? 344 LEU A CD1   1 
ATOM   2510 C CD2   . LEU A 1 344 ? 135.112 139.587 190.824 1.00 90.92  ? 344 LEU A CD2   1 
ATOM   2511 N N     . SER A 1 345 ? 136.388 140.472 194.350 1.00 94.25  ? 345 SER A N     1 
ATOM   2512 C CA    . SER A 1 345 ? 136.664 141.899 194.428 1.00 94.25  ? 345 SER A CA    1 
ATOM   2513 C C     . SER A 1 345 ? 138.088 142.162 194.891 1.00 94.25  ? 345 SER A C     1 
ATOM   2514 O O     . SER A 1 345 ? 138.775 143.029 194.341 1.00 94.25  ? 345 SER A O     1 
ATOM   2515 C CB    . SER A 1 345 ? 135.668 142.566 195.372 1.00 94.25  ? 345 SER A CB    1 
ATOM   2516 O OG    . SER A 1 345 ? 134.338 142.396 194.920 1.00 94.25  ? 345 SER A OG    1 
ATOM   2517 N N     . LYS A 1 346 ? 138.549 141.425 195.904 1.00 87.84  ? 346 LYS A N     1 
ATOM   2518 C CA    . LYS A 1 346 ? 139.910 141.613 196.392 1.00 87.84  ? 346 LYS A CA    1 
ATOM   2519 C C     . LYS A 1 346 ? 140.932 141.275 195.314 1.00 87.84  ? 346 LYS A C     1 
ATOM   2520 O O     . LYS A 1 346 ? 141.909 142.008 195.123 1.00 87.84  ? 346 LYS A O     1 
ATOM   2521 C CB    . LYS A 1 346 ? 140.141 140.760 197.639 1.00 87.84  ? 346 LYS A CB    1 
ATOM   2522 C CG    . LYS A 1 346 ? 141.387 141.131 198.423 1.00 87.84  ? 346 LYS A CG    1 
ATOM   2523 C CD    . LYS A 1 346 ? 141.869 139.971 199.277 1.00 87.84  ? 346 LYS A CD    1 
ATOM   2524 C CE    . LYS A 1 346 ? 142.465 138.867 198.421 1.00 87.84  ? 346 LYS A CE    1 
ATOM   2525 N NZ    . LYS A 1 346 ? 143.514 139.390 197.502 1.00 87.84  ? 346 LYS A NZ    1 
ATOM   2526 N N     . SER A 1 347 ? 140.717 140.173 194.590 1.00 88.68  ? 347 SER A N     1 
ATOM   2527 C CA    . SER A 1 347 ? 141.652 139.781 193.540 1.00 88.68  ? 347 SER A CA    1 
ATOM   2528 C C     . SER A 1 347 ? 141.679 140.808 192.414 1.00 88.68  ? 347 SER A C     1 
ATOM   2529 O O     . SER A 1 347 ? 142.753 141.197 191.936 1.00 88.68  ? 347 SER A O     1 
ATOM   2530 C CB    . SER A 1 347 ? 141.281 138.401 193.001 1.00 88.68  ? 347 SER A CB    1 
ATOM   2531 O OG    . SER A 1 347 ? 139.883 138.300 192.795 1.00 88.68  ? 347 SER A OG    1 
ATOM   2532 N N     . LEU A 1 348 ? 140.502 141.262 191.976 1.00 84.47  ? 348 LEU A N     1 
ATOM   2533 C CA    . LEU A 1 348 ? 140.448 142.265 190.917 1.00 84.47  ? 348 LEU A CA    1 
ATOM   2534 C C     . LEU A 1 348 ? 141.100 143.567 191.362 1.00 84.47  ? 348 LEU A C     1 
ATOM   2535 O O     . LEU A 1 348 ? 141.823 144.205 190.588 1.00 84.47  ? 348 LEU A O     1 
ATOM   2536 C CB    . LEU A 1 348 ? 138.999 142.503 190.491 1.00 84.47  ? 348 LEU A CB    1 
ATOM   2537 C CG    . LEU A 1 348 ? 138.508 141.725 189.267 1.00 84.47  ? 348 LEU A CG    1 
ATOM   2538 C CD1   . LEU A 1 348 ? 138.500 140.228 189.533 1.00 84.47  ? 348 LEU A CD1   1 
ATOM   2539 C CD2   . LEU A 1 348 ? 137.126 142.199 188.844 1.00 84.47  ? 348 LEU A CD2   1 
ATOM   2540 N N     . ASN A 1 349 ? 140.864 143.974 192.611 1.00 88.22  ? 349 ASN A N     1 
ATOM   2541 C CA    . ASN A 1 349 ? 141.488 145.187 193.123 1.00 88.22  ? 349 ASN A CA    1 
ATOM   2542 C C     . ASN A 1 349 ? 143.002 145.047 193.171 1.00 88.22  ? 349 ASN A C     1 
ATOM   2543 O O     . ASN A 1 349 ? 143.727 145.987 192.831 1.00 88.22  ? 349 ASN A O     1 
ATOM   2544 C CB    . ASN A 1 349 ? 140.933 145.517 194.509 1.00 88.22  ? 349 ASN A CB    1 
ATOM   2545 C CG    . ASN A 1 349 ? 139.547 146.126 194.450 1.00 88.22  ? 349 ASN A CG    1 
ATOM   2546 O OD1   . ASN A 1 349 ? 139.034 146.430 193.373 1.00 88.22  ? 349 ASN A OD1   1 
ATOM   2547 N ND2   . ASN A 1 349 ? 138.932 146.309 195.613 1.00 88.22  ? 349 ASN A ND2   1 
ATOM   2548 N N     . LYS A 1 350 ? 143.499 143.882 193.596 1.00 82.34  ? 350 LYS A N     1 
ATOM   2549 C CA    . LYS A 1 350 ? 144.942 143.663 193.622 1.00 82.34  ? 350 LYS A CA    1 
ATOM   2550 C C     . LYS A 1 350 ? 145.528 143.718 192.218 1.00 82.34  ? 350 LYS A C     1 
ATOM   2551 O O     . LYS A 1 350 ? 146.627 144.247 192.015 1.00 82.34  ? 350 LYS A O     1 
ATOM   2552 C CB    . LYS A 1 350 ? 145.259 142.323 194.287 1.00 82.34  ? 350 LYS A CB    1 
ATOM   2553 C CG    . LYS A 1 350 ? 146.747 142.049 194.470 1.00 82.34  ? 350 LYS A CG    1 
ATOM   2554 C CD    . LYS A 1 350 ? 147.460 143.208 195.156 1.00 82.34  ? 350 LYS A CD    1 
ATOM   2555 C CE    . LYS A 1 350 ? 146.934 143.438 196.567 1.00 82.34  ? 350 LYS A CE    1 
ATOM   2556 N NZ    . LYS A 1 350 ? 147.953 144.078 197.445 1.00 82.34  ? 350 LYS A NZ    1 
ATOM   2557 N N     . ILE A 1 351 ? 144.808 143.169 191.236 1.00 87.33  ? 351 ILE A N     1 
ATOM   2558 C CA    . ILE A 1 351 ? 145.262 143.250 189.849 1.00 87.33  ? 351 ILE A CA    1 
ATOM   2559 C C     . ILE A 1 351 ? 145.297 144.700 189.381 1.00 87.33  ? 351 ILE A C     1 
ATOM   2560 O O     . ILE A 1 351 ? 146.216 145.116 188.665 1.00 87.33  ? 351 ILE A O     1 
ATOM   2561 C CB    . ILE A 1 351 ? 144.370 142.381 188.941 1.00 87.33  ? 351 ILE A CB    1 
ATOM   2562 C CG1   . ILE A 1 351 ? 144.557 140.899 189.269 1.00 87.33  ? 351 ILE A CG1   1 
ATOM   2563 C CG2   . ILE A 1 351 ? 144.677 142.638 187.476 1.00 87.33  ? 351 ILE A CG2   1 
ATOM   2564 C CD1   . ILE A 1 351 ? 143.345 140.052 188.963 1.00 87.33  ? 351 ILE A CD1   1 
ATOM   2565 N N     . LEU A 1 352 ? 144.301 145.492 189.776 1.00 85.53  ? 352 LEU A N     1 
ATOM   2566 C CA    . LEU A 1 352 ? 144.186 146.863 189.292 1.00 85.53  ? 352 LEU A CA    1 
ATOM   2567 C C     . LEU A 1 352 ? 145.039 147.863 190.066 1.00 85.53  ? 352 LEU A C     1 
ATOM   2568 O O     . LEU A 1 352 ? 145.167 149.007 189.617 1.00 85.53  ? 352 LEU A O     1 
ATOM   2569 C CB    . LEU A 1 352 ? 142.721 147.309 189.329 1.00 85.53  ? 352 LEU A CB    1 
ATOM   2570 C CG    . LEU A 1 352 ? 141.877 147.084 188.070 1.00 85.53  ? 352 LEU A CG    1 
ATOM   2571 C CD1   . LEU A 1 352 ? 141.789 145.610 187.704 1.00 85.53  ? 352 LEU A CD1   1 
ATOM   2572 C CD2   . LEU A 1 352 ? 140.486 147.674 188.249 1.00 85.53  ? 352 LEU A CD2   1 
ATOM   2573 N N     . GLU A 1 353 ? 145.602 147.477 191.211 1.00 92.98  ? 353 GLU A N     1 
ATOM   2574 C CA    . GLU A 1 353 ? 146.481 148.390 191.945 1.00 92.98  ? 353 GLU A CA    1 
ATOM   2575 C C     . GLU A 1 353 ? 147.627 148.955 191.112 1.00 92.98  ? 353 GLU A C     1 
ATOM   2576 O O     . GLU A 1 353 ? 147.880 150.168 191.221 1.00 92.98  ? 353 GLU A O     1 
ATOM   2577 C CB    . GLU A 1 353 ? 147.047 147.716 193.209 1.00 92.98  ? 353 GLU A CB    1 
ATOM   2578 C CG    . GLU A 1 353 ? 146.043 147.211 194.248 1.00 92.98  ? 353 GLU A CG    1 
ATOM   2579 C CD    . GLU A 1 353 ? 144.912 148.187 194.568 1.00 92.98  ? 353 GLU A CD    1 
ATOM   2580 O OE1   . GLU A 1 353 ? 143.870 147.727 195.080 1.00 92.98  ? 353 GLU A OE1   1 
ATOM   2581 O OE2   . GLU A 1 353 ? 145.072 149.411 194.369 1.00 92.98  ? 353 GLU A OE2   1 
ATOM   2582 N N     . PRO A 1 354 ? 148.361 148.176 190.303 1.00 92.41  ? 354 PRO A N     1 
ATOM   2583 C CA    . PRO A 1 354 ? 149.415 148.801 189.482 1.00 92.41  ? 354 PRO A CA    1 
ATOM   2584 C C     . PRO A 1 354 ? 148.895 149.906 188.582 1.00 92.41  ? 354 PRO A C     1 
ATOM   2585 O O     . PRO A 1 354 ? 149.589 150.908 188.377 1.00 92.41  ? 354 PRO A O     1 
ATOM   2586 C CB    . PRO A 1 354 ? 149.986 147.633 188.663 1.00 92.41  ? 354 PRO A CB    1 
ATOM   2587 C CG    . PRO A 1 354 ? 149.478 146.394 189.272 1.00 92.41  ? 354 PRO A CG    1 
ATOM   2588 C CD    . PRO A 1 354 ? 148.422 146.702 190.275 1.00 92.41  ? 354 PRO A CD    1 
ATOM   2589 N N     . VAL A 1 355 ? 147.679 149.758 188.050 1.00 95.66  ? 355 VAL A N     1 
ATOM   2590 C CA    . VAL A 1 355 ? 147.113 150.784 187.178 1.00 95.66  ? 355 VAL A CA    1 
ATOM   2591 C C     . VAL A 1 355 ? 146.943 152.096 187.938 1.00 95.66  ? 355 VAL A C     1 
ATOM   2592 O O     . VAL A 1 355 ? 147.354 153.166 187.470 1.00 95.66  ? 355 VAL A O     1 
ATOM   2593 C CB    . VAL A 1 355 ? 145.778 150.299 186.584 1.00 95.66  ? 355 VAL A CB    1 
ATOM   2594 C CG1   . VAL A 1 355 ? 145.137 151.392 185.752 1.00 95.66  ? 355 VAL A CG1   1 
ATOM   2595 C CG2   . VAL A 1 355 ? 145.995 149.045 185.750 1.00 95.66  ? 355 VAL A CG2   1 
ATOM   2596 N N     . ARG A 1 356 ? 146.339 152.031 189.127 1.00 95.06  ? 356 ARG A N     1 
ATOM   2597 C CA    . ARG A 1 356 ? 146.115 153.242 189.910 1.00 95.06  ? 356 ARG A CA    1 
ATOM   2598 C C     . ARG A 1 356 ? 147.428 153.848 190.391 1.00 95.06  ? 356 ARG A C     1 
ATOM   2599 O O     . ARG A 1 356 ? 147.582 155.076 190.407 1.00 95.06  ? 356 ARG A O     1 
ATOM   2600 C CB    . ARG A 1 356 ? 145.194 152.942 191.092 1.00 95.06  ? 356 ARG A CB    1 
ATOM   2601 C CG    . ARG A 1 356 ? 144.017 152.043 190.747 1.00 95.06  ? 356 ARG A CG    1 
ATOM   2602 C CD    . ARG A 1 356 ? 143.696 151.091 191.886 1.00 95.06  ? 356 ARG A CD    1 
ATOM   2603 N NE    . ARG A 1 356 ? 142.689 150.106 191.511 1.00 95.06  ? 356 ARG A NE    1 
ATOM   2604 C CZ    . ARG A 1 356 ? 141.381 150.297 191.609 1.00 95.06  ? 356 ARG A CZ    1 
ATOM   2605 N NH1   . ARG A 1 356 ? 140.881 151.440 192.048 1.00 95.06  ? 356 ARG A NH1   1 
ATOM   2606 N NH2   . ARG A 1 356 ? 140.554 149.318 191.256 1.00 95.06  ? 356 ARG A NH2   1 
ATOM   2607 N N     . GLU A 1 357 ? 148.383 153.006 190.796 1.00 101.68 ? 357 GLU A N     1 
ATOM   2608 C CA    . GLU A 1 357 ? 149.681 153.524 191.217 1.00 101.68 ? 357 GLU A CA    1 
ATOM   2609 C C     . GLU A 1 357 ? 150.396 154.222 190.067 1.00 101.68 ? 357 GLU A C     1 
ATOM   2610 O O     . GLU A 1 357 ? 150.998 155.284 190.260 1.00 101.68 ? 357 GLU A O     1 
ATOM   2611 C CB    . GLU A 1 357 ? 150.548 152.402 191.789 1.00 101.68 ? 357 GLU A CB    1 
ATOM   2612 C CG    . GLU A 1 357 ? 149.928 151.679 192.971 1.00 101.68 ? 357 GLU A CG    1 
ATOM   2613 C CD    . GLU A 1 357 ? 149.214 152.621 193.921 1.00 101.68 ? 357 GLU A CD    1 
ATOM   2614 O OE1   . GLU A 1 357 ? 149.891 153.469 194.540 1.00 101.68 ? 357 GLU A OE1   1 
ATOM   2615 O OE2   . GLU A 1 357 ? 147.976 152.515 194.046 1.00 101.68 ? 357 GLU A OE2   1 
ATOM   2616 N N     . HIS A 1 358 ? 150.336 153.648 188.864 1.00 101.69 ? 358 HIS A N     1 
ATOM   2617 C CA    . HIS A 1 358 ? 150.929 154.302 187.704 1.00 101.69 ? 358 HIS A CA    1 
ATOM   2618 C C     . HIS A 1 358 ? 150.230 155.620 187.400 1.00 101.69 ? 358 HIS A C     1 
ATOM   2619 O O     . HIS A 1 358 ? 150.888 156.619 187.090 1.00 101.69 ? 358 HIS A O     1 
ATOM   2620 C CB    . HIS A 1 358 ? 150.875 153.371 186.496 1.00 101.69 ? 358 HIS A CB    1 
ATOM   2621 C CG    . HIS A 1 358 ? 151.598 153.895 185.295 1.00 101.69 ? 358 HIS A CG    1 
ATOM   2622 N ND1   . HIS A 1 358 ? 151.004 154.729 184.372 1.00 101.69 ? 358 HIS A ND1   1 
ATOM   2623 C CD2   . HIS A 1 358 ? 152.867 153.700 184.863 1.00 101.69 ? 358 HIS A CD2   1 
ATOM   2624 C CE1   . HIS A 1 358 ? 151.876 155.026 183.425 1.00 101.69 ? 358 HIS A CE1   1 
ATOM   2625 N NE2   . HIS A 1 358 ? 153.014 154.415 183.700 1.00 101.69 ? 358 HIS A NE2   1 
ATOM   2626 N N     . PHE A 1 359 ? 148.897 155.644 187.496 1.00 97.06  ? 359 PHE A N     1 
ATOM   2627 C CA    . PHE A 1 359 ? 148.167 156.886 187.257 1.00 97.06  ? 359 PHE A CA    1 
ATOM   2628 C C     . PHE A 1 359 ? 148.567 157.969 188.249 1.00 97.06  ? 359 PHE A C     1 
ATOM   2629 O O     . PHE A 1 359 ? 148.738 159.131 187.864 1.00 97.06  ? 359 PHE A O     1 
ATOM   2630 C CB    . PHE A 1 359 ? 146.660 156.640 187.334 1.00 97.06  ? 359 PHE A CB    1 
ATOM   2631 C CG    . PHE A 1 359 ? 146.104 155.890 186.159 1.00 97.06  ? 359 PHE A CG    1 
ATOM   2632 C CD1   . PHE A 1 359 ? 146.867 155.689 185.021 1.00 97.06  ? 359 PHE A CD1   1 
ATOM   2633 C CD2   . PHE A 1 359 ? 144.812 155.395 186.191 1.00 97.06  ? 359 PHE A CD2   1 
ATOM   2634 C CE1   . PHE A 1 359 ? 146.354 154.999 183.941 1.00 97.06  ? 359 PHE A CE1   1 
ATOM   2635 C CE2   . PHE A 1 359 ? 144.292 154.708 185.113 1.00 97.06  ? 359 PHE A CE2   1 
ATOM   2636 C CZ    . PHE A 1 359 ? 145.065 154.508 183.987 1.00 97.06  ? 359 PHE A CZ    1 
ATOM   2637 N N     . ARG A 1 360 ? 148.722 157.610 189.522 1.00 100.57 ? 360 ARG A N     1 
ATOM   2638 C CA    . ARG A 1 360 ? 149.096 158.582 190.541 1.00 100.57 ? 360 ARG A CA    1 
ATOM   2639 C C     . ARG A 1 360 ? 150.562 158.988 190.472 1.00 100.57 ? 360 ARG A C     1 
ATOM   2640 O O     . ARG A 1 360 ? 150.908 160.096 190.897 1.00 100.57 ? 360 ARG A O     1 
ATOM   2641 C CB    . ARG A 1 360 ? 148.782 158.031 191.935 1.00 100.57 ? 360 ARG A CB    1 
ATOM   2642 C CG    . ARG A 1 360 ? 147.312 158.114 192.310 1.00 100.57 ? 360 ARG A CG    1 
ATOM   2643 C CD    . ARG A 1 360 ? 146.983 157.216 193.490 1.00 100.57 ? 360 ARG A CD    1 
ATOM   2644 N NE    . ARG A 1 360 ? 145.573 156.848 193.512 1.00 100.57 ? 360 ARG A NE    1 
ATOM   2645 C CZ    . ARG A 1 360 ? 145.106 155.697 193.978 1.00 100.57 ? 360 ARG A CZ    1 
ATOM   2646 N NH1   . ARG A 1 360 ? 145.913 154.774 194.474 1.00 100.57 ? 360 ARG A NH1   1 
ATOM   2647 N NH2   . ARG A 1 360 ? 143.797 155.467 193.944 1.00 100.57 ? 360 ARG A NH2   1 
ATOM   2648 N N     . LYS A 1 361 ? 151.435 158.124 189.949 1.00 104.93 ? 361 LYS A N     1 
ATOM   2649 C CA    . LYS A 1 361 ? 152.859 158.442 189.921 1.00 104.93 ? 361 LYS A CA    1 
ATOM   2650 C C     . LYS A 1 361 ? 153.252 159.178 188.644 1.00 104.93 ? 361 LYS A C     1 
ATOM   2651 O O     . LYS A 1 361 ? 153.816 160.276 188.704 1.00 104.93 ? 361 LYS A O     1 
ATOM   2652 C CB    . LYS A 1 361 ? 153.686 157.165 190.078 1.00 104.93 ? 361 LYS A CB    1 
ATOM   2653 C CG    . LYS A 1 361 ? 153.683 156.592 191.487 1.00 104.93 ? 361 LYS A CG    1 
ATOM   2654 C CD    . LYS A 1 361 ? 154.916 155.739 191.739 1.00 104.93 ? 361 LYS A CD    1 
ATOM   2655 C CE    . LYS A 1 361 ? 155.046 155.378 193.211 1.00 104.93 ? 361 LYS A CE    1 
ATOM   2656 N NZ    . LYS A 1 361 ? 156.140 154.396 193.449 1.00 104.93 ? 361 LYS A NZ    1 
ATOM   2657 N N     . ASP A 1 362 ? 152.968 158.592 187.482 1.00 112.06 ? 362 ASP A N     1 
ATOM   2658 C CA    . ASP A 1 362 ? 153.418 159.155 186.216 1.00 112.06 ? 362 ASP A CA    1 
ATOM   2659 C C     . ASP A 1 362 ? 152.640 160.429 185.910 1.00 112.06 ? 362 ASP A C     1 
ATOM   2660 O O     . ASP A 1 362 ? 151.411 160.398 185.771 1.00 112.06 ? 362 ASP A O     1 
ATOM   2661 C CB    . ASP A 1 362 ? 153.249 158.135 185.092 1.00 112.06 ? 362 ASP A CB    1 
ATOM   2662 C CG    . ASP A 1 362 ? 153.838 158.610 183.777 1.00 112.06 ? 362 ASP A CG    1 
ATOM   2663 O OD1   . ASP A 1 362 ? 154.646 159.563 183.793 1.00 112.06 ? 362 ASP A OD1   1 
ATOM   2664 O OD2   . ASP A 1 362 ? 153.492 158.030 182.726 1.00 112.06 ? 362 ASP A OD2   1 
ATOM   2665 N N     . SER A 1 363 ? 153.361 161.547 185.804 1.00 115.90 ? 363 SER A N     1 
ATOM   2666 C CA    . SER A 1 363 ? 152.721 162.817 185.478 1.00 115.90 ? 363 SER A CA    1 
ATOM   2667 C C     . SER A 1 363 ? 152.088 162.774 184.094 1.00 115.90 ? 363 SER A C     1 
ATOM   2668 O O     . SER A 1 363 ? 150.984 163.292 183.893 1.00 115.90 ? 363 SER A O     1 
ATOM   2669 C CB    . SER A 1 363 ? 153.737 163.955 185.569 1.00 115.90 ? 363 SER A CB    1 
ATOM   2670 O OG    . SER A 1 363 ? 154.737 163.824 184.573 1.00 115.90 ? 363 SER A OG    1 
ATOM   2671 N N     . ASN A 1 364 ? 152.775 162.164 183.125 1.00 118.68 ? 364 ASN A N     1 
ATOM   2672 C CA    . ASN A 1 364 ? 152.218 162.051 181.781 1.00 118.68 ? 364 ASN A CA    1 
ATOM   2673 C C     . ASN A 1 364 ? 150.944 161.216 181.779 1.00 118.68 ? 364 ASN A C     1 
ATOM   2674 O O     . ASN A 1 364 ? 149.956 161.578 181.128 1.00 118.68 ? 364 ASN A O     1 
ATOM   2675 C CB    . ASN A 1 364 ? 153.256 161.451 180.834 1.00 118.68 ? 364 ASN A CB    1 
ATOM   2676 C CG    . ASN A 1 364 ? 152.708 161.222 179.440 1.00 118.68 ? 364 ASN A CG    1 
ATOM   2677 O OD1   . ASN A 1 364 ? 152.332 162.166 178.745 1.00 118.68 ? 364 ASN A OD1   1 
ATOM   2678 N ND2   . ASN A 1 364 ? 152.659 159.962 179.023 1.00 118.68 ? 364 ASN A ND2   1 
ATOM   2679 N N     . ALA A 1 365 ? 150.945 160.095 182.505 1.00 115.90 ? 365 ALA A N     1 
ATOM   2680 C CA    . ALA A 1 365 ? 149.751 159.259 182.575 1.00 115.90 ? 365 ALA A CA    1 
ATOM   2681 C C     . ALA A 1 365 ? 148.602 159.994 183.252 1.00 115.90 ? 365 ALA A C     1 
ATOM   2682 O O     . ALA A 1 365 ? 147.449 159.898 182.814 1.00 115.90 ? 365 ALA A O     1 
ATOM   2683 C CB    . ALA A 1 365 ? 150.062 157.957 183.310 1.00 115.90 ? 365 ALA A CB    1 
ATOM   2684 N N     . LYS A 1 366 ? 148.896 160.733 184.325 1.00 119.03 ? 366 LYS A N     1 
ATOM   2685 C CA    . LYS A 1 366 ? 147.851 161.496 184.998 1.00 119.03 ? 366 LYS A CA    1 
ATOM   2686 C C     . LYS A 1 366 ? 147.287 162.578 184.086 1.00 119.03 ? 366 LYS A C     1 
ATOM   2687 O O     . LYS A 1 366 ? 146.072 162.809 184.062 1.00 119.03 ? 366 LYS A O     1 
ATOM   2688 C CB    . LYS A 1 366 ? 148.393 162.108 186.290 1.00 119.03 ? 366 LYS A CB    1 
ATOM   2689 C CG    . LYS A 1 366 ? 147.320 162.725 187.168 1.00 119.03 ? 366 LYS A CG    1 
ATOM   2690 C CD    . LYS A 1 366 ? 146.249 161.704 187.520 1.00 119.03 ? 366 LYS A CD    1 
ATOM   2691 C CE    . LYS A 1 366 ? 145.276 162.255 188.548 1.00 119.03 ? 366 LYS A CE    1 
ATOM   2692 N NZ    . LYS A 1 366 ? 144.256 163.143 187.925 1.00 119.03 ? 366 LYS A NZ    1 
ATOM   2693 N N     . GLU A 1 367 ? 148.154 163.253 183.327 1.00 123.92 ? 367 GLU A N     1 
ATOM   2694 C CA    . GLU A 1 367 ? 147.684 164.264 182.386 1.00 123.92 ? 367 GLU A CA    1 
ATOM   2695 C C     . GLU A 1 367 ? 146.815 163.646 181.299 1.00 123.92 ? 367 GLU A C     1 
ATOM   2696 O O     . GLU A 1 367 ? 145.787 164.217 180.918 1.00 123.92 ? 367 GLU A O     1 
ATOM   2697 C CB    . GLU A 1 367 ? 148.873 165.001 181.768 1.00 123.92 ? 367 GLU A CB    1 
ATOM   2698 C CG    . GLU A 1 367 ? 149.552 165.982 182.709 1.00 123.92 ? 367 GLU A CG    1 
ATOM   2699 C CD    . GLU A 1 367 ? 148.675 167.174 183.039 1.00 123.92 ? 367 GLU A CD    1 
ATOM   2700 O OE1   . GLU A 1 367 ? 147.855 167.566 182.182 1.00 123.92 ? 367 GLU A OE1   1 
ATOM   2701 O OE2   . GLU A 1 367 ? 148.806 167.719 184.155 1.00 123.92 ? 367 GLU A OE2   1 
ATOM   2702 N N     . LEU A 1 368 ? 147.214 162.481 180.783 1.00 115.58 ? 368 LEU A N     1 
ATOM   2703 C CA    . LEU A 1 368 ? 146.404 161.807 179.772 1.00 115.58 ? 368 LEU A CA    1 
ATOM   2704 C C     . LEU A 1 368 ? 145.046 161.405 180.334 1.00 115.58 ? 368 LEU A C     1 
ATOM   2705 O O     . LEU A 1 368 ? 144.019 161.546 179.658 1.00 115.58 ? 368 LEU A O     1 
ATOM   2706 C CB    . LEU A 1 368 ? 147.145 160.587 179.227 1.00 115.58 ? 368 LEU A CB    1 
ATOM   2707 C CG    . LEU A 1 368 ? 148.407 160.871 178.411 1.00 115.58 ? 368 LEU A CG    1 
ATOM   2708 C CD1   . LEU A 1 368 ? 149.246 159.612 178.258 1.00 115.58 ? 368 LEU A CD1   1 
ATOM   2709 C CD2   . LEU A 1 368 ? 148.050 161.450 177.051 1.00 115.58 ? 368 LEU A CD2   1 
ATOM   2710 N N     . LEU A 1 369 ? 145.020 160.903 181.571 1.00 114.30 ? 369 LEU A N     1 
ATOM   2711 C CA    . LEU A 1 369 ? 143.751 160.551 182.201 1.00 114.30 ? 369 LEU A CA    1 
ATOM   2712 C C     . LEU A 1 369 ? 142.871 161.781 182.390 1.00 114.30 ? 369 LEU A C     1 
ATOM   2713 O O     . LEU A 1 369 ? 141.654 161.723 182.174 1.00 114.30 ? 369 LEU A O     1 
ATOM   2714 C CB    . LEU A 1 369 ? 144.005 159.858 183.540 1.00 114.30 ? 369 LEU A CB    1 
ATOM   2715 C CG    . LEU A 1 369 ? 142.791 159.641 184.446 1.00 114.30 ? 369 LEU A CG    1 
ATOM   2716 C CD1   . LEU A 1 369 ? 141.746 158.776 183.758 1.00 114.30 ? 369 LEU A CD1   1 
ATOM   2717 C CD2   . LEU A 1 369 ? 143.214 159.024 185.770 1.00 114.30 ? 369 LEU A CD2   1 
ATOM   2718 N N     . LYS A 1 370 ? 143.468 162.902 182.800 1.00 123.26 ? 370 LYS A N     1 
ATOM   2719 C CA    . LYS A 1 370 ? 142.702 164.134 182.961 1.00 123.26 ? 370 LYS A CA    1 
ATOM   2720 C C     . LYS A 1 370 ? 142.135 164.609 181.629 1.00 123.26 ? 370 LYS A C     1 
ATOM   2721 O O     . LYS A 1 370 ? 140.980 165.046 181.558 1.00 123.26 ? 370 LYS A O     1 
ATOM   2722 C CB    . LYS A 1 370 ? 143.575 165.215 183.596 1.00 123.26 ? 370 LYS A CB    1 
ATOM   2723 C CG    . LYS A 1 370 ? 143.838 165.001 185.078 1.00 123.26 ? 370 LYS A CG    1 
ATOM   2724 C CD    . LYS A 1 370 ? 144.628 166.154 185.677 1.00 123.26 ? 370 LYS A CD    1 
ATOM   2725 C CE    . LYS A 1 370 ? 146.115 166.006 185.402 1.00 123.26 ? 370 LYS A CE    1 
ATOM   2726 N NZ    . LYS A 1 370 ? 146.923 167.001 186.161 1.00 123.26 ? 370 LYS A NZ    1 
ATOM   2727 N N     . ARG A 1 371 ? 142.930 164.528 180.559 1.00 124.84 ? 371 ARG A N     1 
ATOM   2728 C CA    . ARG A 1 371 ? 142.429 164.899 179.239 1.00 124.84 ? 371 ARG A CA    1 
ATOM   2729 C C     . ARG A 1 371 ? 141.285 163.990 178.810 1.00 124.84 ? 371 ARG A C     1 
ATOM   2730 O O     . ARG A 1 371 ? 140.284 164.460 178.256 1.00 124.84 ? 371 ARG A O     1 
ATOM   2731 C CB    . ARG A 1 371 ? 143.558 164.857 178.208 1.00 124.84 ? 371 ARG A CB    1 
ATOM   2732 C CG    . ARG A 1 371 ? 144.689 165.837 178.465 1.00 124.84 ? 371 ARG A CG    1 
ATOM   2733 C CD    . ARG A 1 371 ? 145.993 165.328 177.871 1.00 124.84 ? 371 ARG A CD    1 
ATOM   2734 N NE    . ARG A 1 371 ? 147.147 166.078 178.352 1.00 124.84 ? 371 ARG A NE    1 
ATOM   2735 C CZ    . ARG A 1 371 ? 148.324 166.113 177.741 1.00 124.84 ? 371 ARG A CZ    1 
ATOM   2736 N NH1   . ARG A 1 371 ? 148.539 165.449 176.617 1.00 124.84 ? 371 ARG A NH1   1 
ATOM   2737 N NH2   . ARG A 1 371 ? 149.309 166.832 178.271 1.00 124.84 ? 371 ARG A NH2   1 
ATOM   2738 N N     . VAL A 1 372 ? 141.416 162.685 179.059 1.00 119.29 ? 372 VAL A N     1 
ATOM   2739 C CA    . VAL A 1 372 ? 140.359 161.745 178.695 1.00 119.29 ? 372 VAL A CA    1 
ATOM   2740 C C     . VAL A 1 372 ? 139.078 162.064 179.455 1.00 119.29 ? 372 VAL A C     1 
ATOM   2741 O O     . VAL A 1 372 ? 137.981 162.066 178.882 1.00 119.29 ? 372 VAL A O     1 
ATOM   2742 C CB    . VAL A 1 372 ? 140.823 160.298 178.944 1.00 119.29 ? 372 VAL A CB    1 
ATOM   2743 C CG1   . VAL A 1 372 ? 139.635 159.348 178.961 1.00 119.29 ? 372 VAL A CG1   1 
ATOM   2744 C CG2   . VAL A 1 372 ? 141.832 159.878 177.888 1.00 119.29 ? 372 VAL A CG2   1 
ATOM   2745 N N     . LYS A 1 373 ? 139.196 162.344 180.756 1.00 119.04 ? 373 LYS A N     1 
ATOM   2746 C CA    . LYS A 1 373 ? 138.023 162.717 181.540 1.00 119.04 ? 373 LYS A CA    1 
ATOM   2747 C C     . LYS A 1 373 ? 137.418 164.029 181.057 1.00 119.04 ? 373 LYS A C     1 
ATOM   2748 O O     . LYS A 1 373 ? 136.193 164.196 181.096 1.00 119.04 ? 373 LYS A O     1 
ATOM   2749 C CB    . LYS A 1 373 ? 138.387 162.812 183.022 1.00 119.04 ? 373 LYS A CB    1 
ATOM   2750 C CG    . LYS A 1 373 ? 138.794 161.491 183.664 1.00 119.04 ? 373 LYS A CG    1 
ATOM   2751 C CD    . LYS A 1 373 ? 137.620 160.525 183.772 1.00 119.04 ? 373 LYS A CD    1 
ATOM   2752 C CE    . LYS A 1 373 ? 137.732 159.386 182.767 1.00 119.04 ? 373 LYS A CE    1 
ATOM   2753 N NZ    . LYS A 1 373 ? 136.559 158.471 182.828 1.00 119.04 ? 373 LYS A NZ    1 
ATOM   2754 N N     . ALA A 1 374 ? 138.251 164.965 180.602 1.00 128.12 ? 374 ALA A N     1 
ATOM   2755 C CA    . ALA A 1 374 ? 137.751 166.221 180.058 1.00 128.12 ? 374 ALA A CA    1 
ATOM   2756 C C     . ALA A 1 374 ? 137.029 166.038 178.731 1.00 128.12 ? 374 ALA A C     1 
ATOM   2757 O O     . ALA A 1 374 ? 136.059 166.757 178.466 1.00 128.12 ? 374 ALA A O     1 
ATOM   2758 C CB    . ALA A 1 374 ? 138.900 167.216 179.887 1.00 128.12 ? 374 ALA A CB    1 
ATOM   2759 N N     . TYR A 1 375 ? 137.475 165.105 177.896 1.00 126.27 ? 375 TYR A N     1 
ATOM   2760 C CA    . TYR A 1 375 ? 136.812 164.829 176.631 1.00 126.27 ? 375 TYR A CA    1 
ATOM   2761 C C     . TYR A 1 375 ? 135.498 164.096 176.871 1.00 126.27 ? 375 TYR A C     1 
ATOM   2762 O O     . TYR A 1 375 ? 135.340 163.365 177.852 1.00 126.27 ? 375 TYR A O     1 
ATOM   2763 C CB    . TYR A 1 375 ? 137.705 163.997 175.707 1.00 126.27 ? 375 TYR A CB    1 
ATOM   2764 C CG    . TYR A 1 375 ? 139.079 164.582 175.464 1.00 126.27 ? 375 TYR A CG    1 
ATOM   2765 C CD1   . TYR A 1 375 ? 139.269 165.956 175.390 1.00 126.27 ? 375 TYR A CD1   1 
ATOM   2766 C CD2   . TYR A 1 375 ? 140.183 163.758 175.292 1.00 126.27 ? 375 TYR A CD2   1 
ATOM   2767 C CE1   . TYR A 1 375 ? 140.523 166.492 175.164 1.00 126.27 ? 375 TYR A CE1   1 
ATOM   2768 C CE2   . TYR A 1 375 ? 141.441 164.285 175.067 1.00 126.27 ? 375 TYR A CE2   1 
ATOM   2769 C CZ    . TYR A 1 375 ? 141.605 165.652 175.003 1.00 126.27 ? 375 TYR A CZ    1 
ATOM   2770 O OH    . TYR A 1 375 ? 142.855 166.180 174.776 1.00 126.27 ? 375 TYR A OH    1 
ATOM   2771 N N     . ARG A 1 376 ? 134.552 164.300 175.960 1.00 150.58 ? 376 ARG A N     1 
ATOM   2772 C CA    . ARG A 1 376 ? 133.244 163.667 176.031 1.00 150.58 ? 376 ARG A CA    1 
ATOM   2773 C C     . ARG A 1 376 ? 133.203 162.458 175.106 1.00 150.58 ? 376 ARG A C     1 
ATOM   2774 O O     . ARG A 1 376 ? 133.731 162.497 173.991 1.00 150.58 ? 376 ARG A O     1 
ATOM   2775 C CB    . ARG A 1 376 ? 132.137 164.654 175.654 1.00 150.58 ? 376 ARG A CB    1 
ATOM   2776 C CG    . ARG A 1 376 ? 130.751 164.241 176.123 1.00 150.58 ? 376 ARG A CG    1 
ATOM   2777 C CD    . ARG A 1 376 ? 129.800 165.427 176.149 1.00 150.58 ? 376 ARG A CD    1 
ATOM   2778 N NE    . ARG A 1 376 ? 128.518 165.088 176.756 1.00 150.58 ? 376 ARG A NE    1 
ATOM   2779 C CZ    . ARG A 1 376 ? 127.497 164.552 176.101 1.00 150.58 ? 376 ARG A CZ    1 
ATOM   2780 N NH1   . ARG A 1 376 ? 127.572 164.279 174.809 1.00 150.58 ? 376 ARG A NH1   1 
ATOM   2781 N NH2   . ARG A 1 376 ? 126.373 164.285 176.759 1.00 150.58 ? 376 ARG A NH2   1 
ATOM   2782 N N     . VAL A 1 377 ? 132.571 161.385 175.575 1.00 154.77 ? 377 VAL A N     1 
ATOM   2783 C CA    . VAL A 1 377 ? 132.479 160.133 174.833 1.00 154.77 ? 377 VAL A CA    1 
ATOM   2784 C C     . VAL A 1 377 ? 131.105 160.051 174.183 1.00 154.77 ? 377 VAL A C     1 
ATOM   2785 O O     . VAL A 1 377 ? 130.079 160.205 174.857 1.00 154.77 ? 377 VAL A O     1 
ATOM   2786 C CB    . VAL A 1 377 ? 132.729 158.923 175.748 1.00 154.77 ? 377 VAL A CB    1 
ATOM   2787 C CG1   . VAL A 1 377 ? 132.914 157.662 174.919 1.00 154.77 ? 377 VAL A CG1   1 
ATOM   2788 C CG2   . VAL A 1 377 ? 133.941 159.170 176.633 1.00 154.77 ? 377 VAL A CG2   1 
ATOM   2789 N N     . THR A 1 378 ? 131.085 159.807 172.874 1.00 148.67 ? 378 THR A N     1 
ATOM   2790 C CA    . THR A 1 378 ? 129.851 159.699 172.109 1.00 148.67 ? 378 THR A CA    1 
ATOM   2791 C C     . THR A 1 378 ? 129.937 158.482 171.202 1.00 148.67 ? 378 THR A C     1 
ATOM   2792 O O     . THR A 1 378 ? 130.954 158.276 170.531 1.00 148.67 ? 378 THR A O     1 
ATOM   2793 C CB    . THR A 1 378 ? 129.601 160.965 171.278 1.00 148.67 ? 378 THR A CB    1 
ATOM   2794 O OG1   . THR A 1 378 ? 129.411 162.083 172.154 1.00 148.67 ? 378 THR A OG1   1 
ATOM   2795 C CG2   . THR A 1 378 ? 128.367 160.801 170.403 1.00 148.67 ? 378 THR A CG2   1 
ATOM   2796 N N     . LYS A 1 379 ? 128.878 157.679 171.185 1.00 146.56 ? 379 LYS A N     1 
ATOM   2797 C CA    . LYS A 1 379 ? 128.833 156.492 170.340 1.00 146.56 ? 379 LYS A CA    1 
ATOM   2798 C C     . LYS A 1 379 ? 128.489 156.866 168.901 1.00 146.56 ? 379 LYS A C     1 
ATOM   2799 O O     . LYS A 1 379 ? 127.779 157.841 168.654 0.00 146.56 ? 379 LYS A O     1 
ATOM   2800 C CB    . LYS A 1 379 ? 127.817 155.483 170.882 1.00 146.56 ? 379 LYS A CB    1 
ATOM   2801 C CG    . LYS A 1 379 ? 127.852 154.131 170.187 1.00 146.56 ? 379 LYS A CG    1 
ATOM   2802 C CD    . LYS A 1 379 ? 126.838 153.172 170.787 1.00 146.56 ? 379 LYS A CD    1 
ATOM   2803 C CE    . LYS A 1 379 ? 126.941 151.795 170.152 1.00 146.56 ? 379 LYS A CE    1 
ATOM   2804 N NZ    . LYS A 1 379 ? 125.894 150.867 170.662 1.00 146.56 ? 379 LYS A NZ    1 
ATOM   2805 O OXT   . LYS A 1 379 ? 128.910 156.205 167.952 0.00 146.56 ? 379 LYS A OXT   1 
ATOM   2806 N N     . PRO B 1 31  ? 134.058 187.642 130.336 1.00 52.62  ? 31  PRO B N     1 
ATOM   2807 C CA    . PRO B 1 31  ? 133.263 186.768 131.205 1.00 52.62  ? 31  PRO B CA    1 
ATOM   2808 C C     . PRO B 1 31  ? 132.098 186.116 130.468 1.00 52.62  ? 31  PRO B C     1 
ATOM   2809 O O     . PRO B 1 31  ? 131.903 184.907 130.578 1.00 52.62  ? 31  PRO B O     1 
ATOM   2810 C CB    . PRO B 1 31  ? 132.759 187.721 132.291 1.00 52.62  ? 31  PRO B CB    1 
ATOM   2811 C CG    . PRO B 1 31  ? 133.778 188.804 132.336 1.00 52.62  ? 31  PRO B CG    1 
ATOM   2812 C CD    . PRO B 1 31  ? 134.244 188.981 130.921 1.00 52.62  ? 31  PRO B CD    1 
ATOM   2813 N N     . GLU B 1 32  ? 131.327 186.920 129.733 1.00 55.01  ? 32  GLU B N     1 
ATOM   2814 C CA    . GLU B 1 32  ? 130.222 186.369 128.954 1.00 55.01  ? 32  GLU B CA    1 
ATOM   2815 C C     . GLU B 1 32  ? 130.729 185.465 127.838 1.00 55.01  ? 32  GLU B C     1 
ATOM   2816 O O     . GLU B 1 32  ? 130.152 184.401 127.582 1.00 55.01  ? 32  GLU B O     1 
ATOM   2817 C CB    . GLU B 1 32  ? 129.363 187.499 128.386 1.00 55.01  ? 32  GLU B CB    1 
ATOM   2818 C CG    . GLU B 1 32  ? 128.645 188.331 129.440 1.00 55.01  ? 32  GLU B CG    1 
ATOM   2819 C CD    . GLU B 1 32  ? 129.531 189.401 130.046 1.00 55.01  ? 32  GLU B CD    1 
ATOM   2820 O OE1   . GLU B 1 32  ? 130.456 189.873 129.352 1.00 55.01  ? 32  GLU B OE1   1 
ATOM   2821 O OE2   . GLU B 1 32  ? 129.304 189.770 131.218 1.00 55.01  ? 32  GLU B OE2   1 
ATOM   2822 N N     . GLU B 1 33  ? 131.807 185.869 127.161 1.00 52.08  ? 33  GLU B N     1 
ATOM   2823 C CA    . GLU B 1 33  ? 132.390 185.006 126.140 1.00 52.08  ? 33  GLU B CA    1 
ATOM   2824 C C     . GLU B 1 33  ? 132.904 183.709 126.750 1.00 52.08  ? 33  GLU B C     1 
ATOM   2825 O O     . GLU B 1 33  ? 132.780 182.641 126.137 1.00 52.08  ? 33  GLU B O     1 
ATOM   2826 C CB    . GLU B 1 33  ? 133.505 185.746 125.392 1.00 52.08  ? 33  GLU B CB    1 
ATOM   2827 C CG    . GLU B 1 33  ? 134.822 185.912 126.151 1.00 52.08  ? 33  GLU B CG    1 
ATOM   2828 C CD    . GLU B 1 33  ? 134.771 186.996 127.214 1.00 52.08  ? 33  GLU B CD    1 
ATOM   2829 O OE1   . GLU B 1 33  ? 135.798 187.210 127.893 1.00 52.08  ? 33  GLU B OE1   1 
ATOM   2830 O OE2   . GLU B 1 33  ? 133.711 187.637 127.370 1.00 52.08  ? 33  GLU B OE2   1 
ATOM   2831 N N     . LYS B 1 34  ? 133.461 183.779 127.962 1.00 44.40  ? 34  LYS B N     1 
ATOM   2832 C CA    . LYS B 1 34  ? 133.838 182.565 128.674 1.00 44.40  ? 34  LYS B CA    1 
ATOM   2833 C C     . LYS B 1 34  ? 132.619 181.692 128.927 1.00 44.40  ? 34  LYS B C     1 
ATOM   2834 O O     . LYS B 1 34  ? 132.681 180.467 128.775 1.00 44.40  ? 34  LYS B O     1 
ATOM   2835 C CB    . LYS B 1 34  ? 134.525 182.920 129.992 1.00 44.40  ? 34  LYS B CB    1 
ATOM   2836 C CG    . LYS B 1 34  ? 136.038 183.004 129.915 1.00 44.40  ? 34  LYS B CG    1 
ATOM   2837 C CD    . LYS B 1 34  ? 136.623 183.370 131.268 1.00 44.40  ? 34  LYS B CD    1 
ATOM   2838 C CE    . LYS B 1 34  ? 137.906 184.168 131.126 1.00 44.40  ? 34  LYS B CE    1 
ATOM   2839 N NZ    . LYS B 1 34  ? 138.392 184.665 132.442 1.00 44.40  ? 34  LYS B NZ    1 
ATOM   2840 N N     . PHE B 1 35  ? 131.498 182.309 129.312 1.00 40.31  ? 35  PHE B N     1 
ATOM   2841 C CA    . PHE B 1 35  ? 130.262 181.558 129.500 1.00 40.31  ? 35  PHE B CA    1 
ATOM   2842 C C     . PHE B 1 35  ? 129.867 180.823 128.227 1.00 40.31  ? 35  PHE B C     1 
ATOM   2843 O O     . PHE B 1 35  ? 129.578 179.623 128.264 1.00 40.31  ? 35  PHE B O     1 
ATOM   2844 C CB    . PHE B 1 35  ? 129.137 182.497 129.939 1.00 40.31  ? 35  PHE B CB    1 
ATOM   2845 C CG    . PHE B 1 35  ? 127.802 181.819 130.110 1.00 40.31  ? 35  PHE B CG    1 
ATOM   2846 C CD1   . PHE B 1 35  ? 127.719 180.498 130.519 1.00 40.31  ? 35  PHE B CD1   1 
ATOM   2847 C CD2   . PHE B 1 35  ? 126.629 182.502 129.840 1.00 40.31  ? 35  PHE B CD2   1 
ATOM   2848 C CE1   . PHE B 1 35  ? 126.495 179.877 130.670 1.00 40.31  ? 35  PHE B CE1   1 
ATOM   2849 C CE2   . PHE B 1 35  ? 125.400 181.886 129.988 1.00 40.31  ? 35  PHE B CE2   1 
ATOM   2850 C CZ    . PHE B 1 35  ? 125.334 180.571 130.404 1.00 40.31  ? 35  PHE B CZ    1 
ATOM   2851 N N     . LYS B 1 36  ? 129.844 181.525 127.093 1.00 38.30  ? 36  LYS B N     1 
ATOM   2852 C CA    . LYS B 1 36  ? 129.433 180.885 125.845 1.00 38.30  ? 36  LYS B CA    1 
ATOM   2853 C C     . LYS B 1 36  ? 130.367 179.739 125.474 1.00 38.30  ? 36  LYS B C     1 
ATOM   2854 O O     . LYS B 1 36  ? 129.914 178.632 125.152 1.00 38.30  ? 36  LYS B O     1 
ATOM   2855 C CB    . LYS B 1 36  ? 129.361 181.914 124.715 1.00 38.30  ? 36  LYS B CB    1 
ATOM   2856 C CG    . LYS B 1 36  ? 128.023 182.639 124.606 1.00 38.30  ? 36  LYS B CG    1 
ATOM   2857 C CD    . LYS B 1 36  ? 127.793 183.617 125.743 1.00 38.30  ? 36  LYS B CD    1 
ATOM   2858 C CE    . LYS B 1 36  ? 126.481 184.364 125.575 1.00 38.30  ? 36  LYS B CE    1 
ATOM   2859 N NZ    . LYS B 1 36  ? 126.175 185.221 126.753 1.00 38.30  ? 36  LYS B NZ    1 
ATOM   2860 N N     . ILE B 1 37  ? 131.680 179.978 125.535 1.00 34.90  ? 37  ILE B N     1 
ATOM   2861 C CA    . ILE B 1 37  ? 132.637 178.950 125.128 1.00 34.90  ? 37  ILE B CA    1 
ATOM   2862 C C     . ILE B 1 37  ? 132.540 177.732 126.040 1.00 34.90  ? 37  ILE B C     1 
ATOM   2863 O O     . ILE B 1 37  ? 132.520 176.587 125.573 1.00 34.90  ? 37  ILE B O     1 
ATOM   2864 C CB    . ILE B 1 37  ? 134.065 179.522 125.093 1.00 34.90  ? 37  ILE B CB    1 
ATOM   2865 C CG1   . ILE B 1 37  ? 134.137 180.719 124.145 1.00 34.90  ? 37  ILE B CG1   1 
ATOM   2866 C CG2   . ILE B 1 37  ? 135.050 178.455 124.661 1.00 34.90  ? 37  ILE B CG2   1 
ATOM   2867 C CD1   . ILE B 1 37  ? 135.444 181.477 124.213 1.00 34.90  ? 37  ILE B CD1   1 
ATOM   2868 N N     . VAL B 1 38  ? 132.472 177.957 127.354 1.00 28.67  ? 38  VAL B N     1 
ATOM   2869 C CA    . VAL B 1 38  ? 132.419 176.844 128.298 1.00 28.67  ? 38  VAL B CA    1 
ATOM   2870 C C     . VAL B 1 38  ? 131.109 176.079 128.157 1.00 28.67  ? 38  VAL B C     1 
ATOM   2871 O O     . VAL B 1 38  ? 131.093 174.842 128.172 1.00 28.67  ? 38  VAL B O     1 
ATOM   2872 C CB    . VAL B 1 38  ? 132.631 177.358 129.733 1.00 28.67  ? 38  VAL B CB    1 
ATOM   2873 C CG1   . VAL B 1 38  ? 132.175 176.327 130.743 1.00 28.67  ? 38  VAL B CG1   1 
ATOM   2874 C CG2   . VAL B 1 38  ? 134.092 177.710 129.953 1.00 28.67  ? 38  VAL B CG2   1 
ATOM   2875 N N     . ARG B 1 39  ? 129.992 176.795 128.016 1.00 29.34  ? 39  ARG B N     1 
ATOM   2876 C CA    . ARG B 1 39  ? 128.697 176.135 127.895 1.00 29.34  ? 39  ARG B CA    1 
ATOM   2877 C C     . ARG B 1 39  ? 128.608 175.332 126.605 1.00 29.34  ? 39  ARG B C     1 
ATOM   2878 O O     . ARG B 1 39  ? 127.922 174.305 126.551 1.00 29.34  ? 39  ARG B O     1 
ATOM   2879 C CB    . ARG B 1 39  ? 127.579 177.176 127.966 1.00 29.34  ? 39  ARG B CB    1 
ATOM   2880 C CG    . ARG B 1 39  ? 126.180 176.617 127.789 1.00 29.34  ? 39  ARG B CG    1 
ATOM   2881 C CD    . ARG B 1 39  ? 125.900 175.511 128.786 1.00 29.34  ? 39  ARG B CD    1 
ATOM   2882 N NE    . ARG B 1 39  ? 124.565 174.951 128.622 1.00 29.34  ? 39  ARG B NE    1 
ATOM   2883 C CZ    . ARG B 1 39  ? 124.258 173.986 127.767 1.00 29.34  ? 39  ARG B CZ    1 
ATOM   2884 N NH1   . ARG B 1 39  ? 125.170 173.448 126.976 1.00 29.34  ? 39  ARG B NH1   1 
ATOM   2885 N NH2   . ARG B 1 39  ? 123.004 173.549 127.705 1.00 29.34  ? 39  ARG B NH2   1 
ATOM   2886 N N     . SER B 1 40  ? 129.305 175.776 125.556 1.00 30.19  ? 40  SER B N     1 
ATOM   2887 C CA    . SER B 1 40  ? 129.283 175.040 124.298 1.00 30.19  ? 40  SER B CA    1 
ATOM   2888 C C     . SER B 1 40  ? 129.939 173.669 124.412 1.00 30.19  ? 40  SER B C     1 
ATOM   2889 O O     . SER B 1 40  ? 129.760 172.836 123.517 1.00 30.19  ? 40  SER B O     1 
ATOM   2890 C CB    . SER B 1 40  ? 129.970 175.855 123.202 1.00 30.19  ? 40  SER B CB    1 
ATOM   2891 O OG    . SER B 1 40  ? 131.379 175.760 123.308 1.00 30.19  ? 40  SER B OG    1 
ATOM   2892 N N     . VAL B 1 41  ? 130.694 173.417 125.485 1.00 27.25  ? 41  VAL B N     1 
ATOM   2893 C CA    . VAL B 1 41  ? 131.404 172.147 125.618 1.00 27.25  ? 41  VAL B CA    1 
ATOM   2894 C C     . VAL B 1 41  ? 130.427 170.991 125.786 1.00 27.25  ? 41  VAL B C     1 
ATOM   2895 O O     . VAL B 1 41  ? 130.533 169.967 125.101 1.00 27.25  ? 41  VAL B O     1 
ATOM   2896 C CB    . VAL B 1 41  ? 132.401 172.212 126.789 1.00 27.25  ? 41  VAL B CB    1 
ATOM   2897 C CG1   . VAL B 1 41  ? 133.012 170.850 127.034 1.00 27.25  ? 41  VAL B CG1   1 
ATOM   2898 C CG2   . VAL B 1 41  ? 133.485 173.231 126.502 1.00 27.25  ? 41  VAL B CG2   1 
ATOM   2899 N N     . GLY B 1 42  ? 129.461 171.132 126.692 1.00 31.51  ? 42  GLY B N     1 
ATOM   2900 C CA    . GLY B 1 42  ? 128.567 170.044 127.014 1.00 31.51  ? 42  GLY B CA    1 
ATOM   2901 C C     . GLY B 1 42  ? 127.127 170.387 126.693 1.00 31.51  ? 42  GLY B C     1 
ATOM   2902 O O     . GLY B 1 42  ? 126.719 171.548 126.700 1.00 31.51  ? 42  GLY B O     1 
ATOM   2903 N N     . GLU B 1 43  ? 126.354 169.339 126.410 1.00 42.79  ? 43  GLU B N     1 
ATOM   2904 C CA    . GLU B 1 43  ? 124.940 169.497 126.098 1.00 42.79  ? 43  GLU B CA    1 
ATOM   2905 C C     . GLU B 1 43  ? 124.086 169.732 127.336 1.00 42.79  ? 43  GLU B C     1 
ATOM   2906 O O     . GLU B 1 43  ? 123.029 170.366 127.236 1.00 42.79  ? 43  GLU B O     1 
ATOM   2907 C CB    . GLU B 1 43  ? 124.426 168.270 125.340 1.00 42.79  ? 43  GLU B CB    1 
ATOM   2908 C CG    . GLU B 1 43  ? 124.233 167.031 126.197 1.00 42.79  ? 43  GLU B CG    1 
ATOM   2909 C CD    . GLU B 1 43  ? 123.636 165.875 125.421 1.00 42.79  ? 43  GLU B CD    1 
ATOM   2910 O OE1   . GLU B 1 43  ? 122.983 166.126 124.386 1.00 42.79  ? 43  GLU B OE1   1 
ATOM   2911 O OE2   . GLU B 1 43  ? 123.815 164.715 125.847 1.00 42.79  ? 43  GLU B OE2   1 
ATOM   2912 N N     . GLU B 1 44  ? 124.514 169.240 128.497 1.00 41.57  ? 44  GLU B N     1 
ATOM   2913 C CA    . GLU B 1 44  ? 123.787 169.410 129.751 1.00 41.57  ? 44  GLU B CA    1 
ATOM   2914 C C     . GLU B 1 44  ? 124.695 170.129 130.739 1.00 41.57  ? 44  GLU B C     1 
ATOM   2915 O O     . GLU B 1 44  ? 125.782 169.639 131.061 1.00 41.57  ? 44  GLU B O     1 
ATOM   2916 C CB    . GLU B 1 44  ? 123.332 168.065 130.310 1.00 41.57  ? 44  GLU B CB    1 
ATOM   2917 C CG    . GLU B 1 44  ? 122.889 168.130 131.761 1.00 41.57  ? 44  GLU B CG    1 
ATOM   2918 C CD    . GLU B 1 44  ? 123.113 166.827 132.498 1.00 41.57  ? 44  GLU B CD    1 
ATOM   2919 O OE1   . GLU B 1 44  ? 123.573 165.856 131.863 1.00 41.57  ? 44  GLU B OE1   1 
ATOM   2920 O OE2   . GLU B 1 44  ? 122.831 166.773 133.713 1.00 41.57  ? 44  GLU B OE2   1 
ATOM   2921 N N     . CYS B 1 45  ? 124.249 171.284 131.219 1.00 39.88  ? 45  CYS B N     1 
ATOM   2922 C CA    . CYS B 1 45  ? 124.995 172.077 132.193 1.00 39.88  ? 45  CYS B CA    1 
ATOM   2923 C C     . CYS B 1 45  ? 124.112 172.283 133.418 1.00 39.88  ? 45  CYS B C     1 
ATOM   2924 O O     . CYS B 1 45  ? 123.234 173.151 133.420 1.00 39.88  ? 45  CYS B O     1 
ATOM   2925 C CB    . CYS B 1 45  ? 125.433 173.408 131.597 1.00 39.88  ? 45  CYS B CB    1 
ATOM   2926 S SG    . CYS B 1 45  ? 126.354 174.451 132.742 1.00 39.88  ? 45  CYS B SG    1 
ATOM   2927 N N     . ILE B 1 46  ? 124.346 171.485 134.458 1.00 44.94  ? 46  ILE B N     1 
ATOM   2928 C CA    . ILE B 1 46  ? 123.582 171.620 135.690 1.00 44.94  ? 46  ILE B CA    1 
ATOM   2929 C C     . ILE B 1 46  ? 124.005 172.896 136.404 1.00 44.94  ? 46  ILE B C     1 
ATOM   2930 O O     . ILE B 1 46  ? 125.202 173.158 136.582 1.00 44.94  ? 46  ILE B O     1 
ATOM   2931 C CB    . ILE B 1 46  ? 123.777 170.382 136.578 1.00 44.94  ? 46  ILE B CB    1 
ATOM   2932 C CG1   . ILE B 1 46  ? 122.999 169.196 136.006 1.00 44.94  ? 46  ILE B CG1   1 
ATOM   2933 C CG2   . ILE B 1 46  ? 123.341 170.668 138.004 1.00 44.94  ? 46  ILE B CG2   1 
ATOM   2934 C CD1   . ILE B 1 46  ? 123.029 167.966 136.882 1.00 44.94  ? 46  ILE B CD1   1 
ATOM   2935 N N     . GLN B 1 47  ? 123.019 173.698 136.812 1.00 45.81  ? 47  GLN B N     1 
ATOM   2936 C CA    . GLN B 1 47  ? 123.241 174.965 137.511 1.00 45.81  ? 47  GLN B CA    1 
ATOM   2937 C C     . GLN B 1 47  ? 124.076 175.925 136.656 1.00 45.81  ? 47  GLN B C     1 
ATOM   2938 O O     . GLN B 1 47  ? 125.218 176.271 136.970 1.00 45.81  ? 47  GLN B O     1 
ATOM   2939 C CB    . GLN B 1 47  ? 123.887 174.731 138.882 1.00 45.81  ? 47  GLN B CB    1 
ATOM   2940 C CG    . GLN B 1 47  ? 123.028 173.919 139.836 1.00 45.81  ? 47  GLN B CG    1 
ATOM   2941 C CD    . GLN B 1 47  ? 121.718 174.603 140.170 1.00 45.81  ? 47  GLN B CD    1 
ATOM   2942 O OE1   . GLN B 1 47  ? 120.658 174.211 139.683 1.00 45.81  ? 47  GLN B OE1   1 
ATOM   2943 N NE2   . GLN B 1 47  ? 121.783 175.633 141.007 1.00 45.81  ? 47  GLN B NE2   1 
ATOM   2944 N N     . GLU B 1 48  ? 123.462 176.334 135.542 1.00 54.35  ? 48  GLU B N     1 
ATOM   2945 C CA    . GLU B 1 48  ? 124.092 177.316 134.666 1.00 54.35  ? 48  GLU B CA    1 
ATOM   2946 C C     . GLU B 1 48  ? 124.354 178.630 135.391 1.00 54.35  ? 48  GLU B C     1 
ATOM   2947 O O     . GLU B 1 48  ? 125.344 179.309 135.103 1.00 54.35  ? 48  GLU B O     1 
ATOM   2948 C CB    . GLU B 1 48  ? 123.225 177.556 133.429 1.00 54.35  ? 48  GLU B CB    1 
ATOM   2949 C CG    . GLU B 1 48  ? 122.847 176.293 132.673 1.00 54.35  ? 48  GLU B CG    1 
ATOM   2950 C CD    . GLU B 1 48  ? 121.566 175.663 133.184 1.00 54.35  ? 48  GLU B CD    1 
ATOM   2951 O OE1   . GLU B 1 48  ? 121.163 175.968 134.325 1.00 54.35  ? 48  GLU B OE1   1 
ATOM   2952 O OE2   . GLU B 1 48  ? 120.964 174.857 132.443 1.00 54.35  ? 48  GLU B OE2   1 
ATOM   2953 N N     . ASP B 1 49  ? 123.484 179.007 136.332 1.00 54.29  ? 49  ASP B N     1 
ATOM   2954 C CA    . ASP B 1 49  ? 123.744 180.198 137.136 1.00 54.29  ? 49  ASP B CA    1 
ATOM   2955 C C     . ASP B 1 49  ? 125.000 180.030 137.984 1.00 54.29  ? 49  ASP B C     1 
ATOM   2956 O O     . ASP B 1 49  ? 125.804 180.962 138.112 1.00 54.29  ? 49  ASP B O     1 
ATOM   2957 C CB    . ASP B 1 49  ? 122.527 180.521 138.006 1.00 54.29  ? 49  ASP B CB    1 
ATOM   2958 C CG    . ASP B 1 49  ? 122.205 179.423 139.010 1.00 54.29  ? 49  ASP B CG    1 
ATOM   2959 O OD1   . ASP B 1 49  ? 122.893 178.381 139.017 1.00 54.29  ? 49  ASP B OD1   1 
ATOM   2960 O OD2   . ASP B 1 49  ? 121.255 179.607 139.800 1.00 54.29  ? 49  ASP B OD2   1 
ATOM   2961 N N     . GLU B 1 50  ? 125.187 178.845 138.569 1.00 46.87  ? 50  GLU B N     1 
ATOM   2962 C CA    . GLU B 1 50  ? 126.408 178.579 139.319 1.00 46.87  ? 50  GLU B CA    1 
ATOM   2963 C C     . GLU B 1 50  ? 127.633 178.583 138.414 1.00 46.87  ? 50  GLU B C     1 
ATOM   2964 O O     . GLU B 1 50  ? 128.698 179.054 138.823 1.00 46.87  ? 50  GLU B O     1 
ATOM   2965 C CB    . GLU B 1 50  ? 126.293 177.248 140.062 1.00 46.87  ? 50  GLU B CB    1 
ATOM   2966 C CG    . GLU B 1 50  ? 125.238 177.237 141.154 1.00 46.87  ? 50  GLU B CG    1 
ATOM   2967 C CD    . GLU B 1 50  ? 125.172 175.910 141.883 1.00 46.87  ? 50  GLU B CD    1 
ATOM   2968 O OE1   . GLU B 1 50  ? 125.925 174.988 141.506 1.00 46.87  ? 50  GLU B OE1   1 
ATOM   2969 O OE2   . GLU B 1 50  ? 124.369 175.791 142.832 1.00 46.87  ? 50  GLU B OE2   1 
ATOM   2970 N N     . LEU B 1 51  ? 127.505 178.066 137.189 1.00 43.45  ? 51  LEU B N     1 
ATOM   2971 C CA    . LEU B 1 51  ? 128.614 178.150 136.242 1.00 43.45  ? 51  LEU B CA    1 
ATOM   2972 C C     . LEU B 1 51  ? 128.940 179.600 135.907 1.00 43.45  ? 51  LEU B C     1 
ATOM   2973 O O     . LEU B 1 51  ? 130.114 179.969 135.784 1.00 43.45  ? 51  LEU B O     1 
ATOM   2974 C CB    . LEU B 1 51  ? 128.290 177.358 134.972 1.00 43.45  ? 51  LEU B CB    1 
ATOM   2975 C CG    . LEU B 1 51  ? 129.389 177.302 133.905 1.00 43.45  ? 51  LEU B CG    1 
ATOM   2976 C CD1   . LEU B 1 51  ? 129.491 175.927 133.280 1.00 43.45  ? 51  LEU B CD1   1 
ATOM   2977 C CD2   . LEU B 1 51  ? 129.121 178.326 132.826 1.00 43.45  ? 51  LEU B CD2   1 
ATOM   2978 N N     . LEU B 1 52  ? 127.911 180.434 135.745 1.00 44.66  ? 52  LEU B N     1 
ATOM   2979 C CA    . LEU B 1 52  ? 128.130 181.857 135.509 1.00 44.66  ? 52  LEU B CA    1 
ATOM   2980 C C     . LEU B 1 52  ? 128.871 182.500 136.674 1.00 44.66  ? 52  LEU B C     1 
ATOM   2981 O O     . LEU B 1 52  ? 129.822 183.264 136.475 1.00 44.66  ? 52  LEU B O     1 
ATOM   2982 C CB    . LEU B 1 52  ? 126.795 182.560 135.269 1.00 44.66  ? 52  LEU B CB    1 
ATOM   2983 C CG    . LEU B 1 52  ? 126.382 182.729 133.811 1.00 44.66  ? 52  LEU B CG    1 
ATOM   2984 C CD1   . LEU B 1 52  ? 125.056 183.458 133.712 1.00 44.66  ? 52  LEU B CD1   1 
ATOM   2985 C CD2   . LEU B 1 52  ? 127.465 183.500 133.083 1.00 44.66  ? 52  LEU B CD2   1 
ATOM   2986 N N     . ASN B 1 53  ? 128.444 182.200 137.903 1.00 46.57  ? 53  ASN B N     1 
ATOM   2987 C CA    . ASN B 1 53  ? 129.128 182.747 139.072 1.00 46.57  ? 53  ASN B CA    1 
ATOM   2988 C C     . ASN B 1 53  ? 130.579 182.286 139.125 1.00 46.57  ? 53  ASN B C     1 
ATOM   2989 O O     . ASN B 1 53  ? 131.482 183.078 139.425 1.00 46.57  ? 53  ASN B O     1 
ATOM   2990 C CB    . ASN B 1 53  ? 128.392 182.350 140.353 1.00 46.57  ? 53  ASN B CB    1 
ATOM   2991 C CG    . ASN B 1 53  ? 127.020 182.981 140.456 1.00 46.57  ? 53  ASN B CG    1 
ATOM   2992 O OD1   . ASN B 1 53  ? 126.012 182.287 140.583 1.00 46.57  ? 53  ASN B OD1   1 
ATOM   2993 N ND2   . ASN B 1 53  ? 126.974 184.307 140.403 1.00 46.57  ? 53  ASN B ND2   1 
ATOM   2994 N N     . LEU B 1 54  ? 130.817 181.006 138.832 1.00 45.35  ? 54  LEU B N     1 
ATOM   2995 C CA    . LEU B 1 54  ? 132.173 180.469 138.847 1.00 45.35  ? 54  LEU B CA    1 
ATOM   2996 C C     . LEU B 1 54  ? 133.050 181.157 137.811 1.00 45.35  ? 54  LEU B C     1 
ATOM   2997 O O     . LEU B 1 54  ? 134.198 181.515 138.093 1.00 45.35  ? 54  LEU B O     1 
ATOM   2998 C CB    . LEU B 1 54  ? 132.136 178.963 138.602 1.00 45.35  ? 54  LEU B CB    1 
ATOM   2999 C CG    . LEU B 1 54  ? 133.486 178.299 138.342 1.00 45.35  ? 54  LEU B CG    1 
ATOM   3000 C CD1   . LEU B 1 54  ? 134.377 178.389 139.569 1.00 45.35  ? 54  LEU B CD1   1 
ATOM   3001 C CD2   . LEU B 1 54  ? 133.277 176.859 137.932 1.00 45.35  ? 54  LEU B CD2   1 
ATOM   3002 N N     . LEU B 1 55  ? 132.527 181.352 136.600 1.00 45.26  ? 55  LEU B N     1 
ATOM   3003 C CA    . LEU B 1 55  ? 133.320 182.002 135.566 1.00 45.26  ? 55  LEU B CA    1 
ATOM   3004 C C     . LEU B 1 55  ? 133.509 183.489 135.831 1.00 45.26  ? 55  LEU B C     1 
ATOM   3005 O O     . LEU B 1 55  ? 134.489 184.069 135.353 1.00 45.26  ? 55  LEU B O     1 
ATOM   3006 C CB    . LEU B 1 55  ? 132.682 181.789 134.194 1.00 45.26  ? 55  LEU B CB    1 
ATOM   3007 C CG    . LEU B 1 55  ? 133.001 180.441 133.547 1.00 45.26  ? 55  LEU B CG    1 
ATOM   3008 C CD1   . LEU B 1 55  ? 132.117 180.201 132.344 1.00 45.26  ? 55  LEU B CD1   1 
ATOM   3009 C CD2   . LEU B 1 55  ? 134.466 180.379 133.152 1.00 45.26  ? 55  LEU B CD2   1 
ATOM   3010 N N     . THR B 1 56  ? 132.598 184.119 136.575 1.00 47.97  ? 56  THR B N     1 
ATOM   3011 C CA    . THR B 1 56  ? 132.789 185.524 136.915 1.00 47.97  ? 56  THR B CA    1 
ATOM   3012 C C     . THR B 1 56  ? 133.820 185.697 138.025 1.00 47.97  ? 56  THR B C     1 
ATOM   3013 O O     . THR B 1 56  ? 134.612 186.646 137.996 1.00 47.97  ? 56  THR B O     1 
ATOM   3014 C CB    . THR B 1 56  ? 131.460 186.162 137.320 1.00 47.97  ? 56  THR B CB    1 
ATOM   3015 O OG1   . THR B 1 56  ? 130.805 185.337 138.290 1.00 47.97  ? 56  THR B OG1   1 
ATOM   3016 C CG2   . THR B 1 56  ? 130.558 186.340 136.107 1.00 47.97  ? 56  THR B CG2   1 
ATOM   3017 N N     . LYS B 1 57  ? 133.832 184.796 139.010 1.00 50.80  ? 57  LYS B N     1 
ATOM   3018 C CA    . LYS B 1 57  ? 134.705 185.011 140.161 1.00 50.80  ? 57  LYS B CA    1 
ATOM   3019 C C     . LYS B 1 57  ? 136.069 184.338 140.019 1.00 50.80  ? 57  LYS B C     1 
ATOM   3020 O O     . LYS B 1 57  ? 137.089 184.940 140.369 1.00 50.80  ? 57  LYS B O     1 
ATOM   3021 C CB    . LYS B 1 57  ? 134.014 184.545 141.449 1.00 50.80  ? 57  LYS B CB    1 
ATOM   3022 C CG    . LYS B 1 57  ? 133.750 183.051 141.557 1.00 50.80  ? 57  LYS B CG    1 
ATOM   3023 C CD    . LYS B 1 57  ? 133.413 182.660 142.986 1.00 50.80  ? 57  LYS B CD    1 
ATOM   3024 C CE    . LYS B 1 57  ? 132.521 181.430 143.029 1.00 50.80  ? 57  LYS B CE    1 
ATOM   3025 N NZ    . LYS B 1 57  ? 131.230 181.658 142.323 1.00 50.80  ? 57  LYS B NZ    1 
ATOM   3026 N N     . LYS B 1 58  ? 136.118 183.105 139.513 1.00 51.29  ? 58  LYS B N     1 
ATOM   3027 C CA    . LYS B 1 58  ? 137.370 182.364 139.394 1.00 51.29  ? 58  LYS B CA    1 
ATOM   3028 C C     . LYS B 1 58  ? 138.024 182.654 138.049 1.00 51.29  ? 58  LYS B C     1 
ATOM   3029 O O     . LYS B 1 58  ? 137.405 182.418 137.005 1.00 51.29  ? 58  LYS B O     1 
ATOM   3030 C CB    . LYS B 1 58  ? 137.124 180.868 139.531 1.00 51.29  ? 58  LYS B CB    1 
ATOM   3031 C CG    . LYS B 1 58  ? 138.390 180.030 139.597 1.00 51.29  ? 58  LYS B CG    1 
ATOM   3032 C CD    . LYS B 1 58  ? 139.284 180.465 140.747 1.00 51.29  ? 58  LYS B CD    1 
ATOM   3033 C CE    . LYS B 1 58  ? 138.684 180.082 142.090 1.00 51.29  ? 58  LYS B CE    1 
ATOM   3034 N NZ    . LYS B 1 58  ? 139.014 181.076 143.148 1.00 51.29  ? 58  LYS B NZ    1 
ATOM   3035 N N     . PRO B 1 59  ? 139.256 183.169 138.033 1.00 46.38  ? 59  PRO B N     1 
ATOM   3036 C CA    . PRO B 1 59  ? 139.935 183.430 136.756 1.00 46.38  ? 59  PRO B CA    1 
ATOM   3037 C C     . PRO B 1 59  ? 140.092 182.180 135.905 1.00 46.38  ? 59  PRO B C     1 
ATOM   3038 O O     . PRO B 1 59  ? 139.658 182.152 134.750 1.00 46.38  ? 59  PRO B O     1 
ATOM   3039 C CB    . PRO B 1 59  ? 141.300 183.987 137.189 1.00 46.38  ? 59  PRO B CB    1 
ATOM   3040 C CG    . PRO B 1 59  ? 141.444 183.602 138.632 1.00 46.38  ? 59  PRO B CG    1 
ATOM   3041 C CD    . PRO B 1 59  ? 140.059 183.611 139.183 1.00 46.38  ? 59  PRO B CD    1 
ATOM   3042 N N     . GLU B 1 60  ? 140.708 181.141 136.464 1.00 46.90  ? 60  GLU B N     1 
ATOM   3043 C CA    . GLU B 1 60  ? 140.914 179.894 135.737 1.00 46.90  ? 60  GLU B CA    1 
ATOM   3044 C C     . GLU B 1 60  ? 140.185 178.745 136.421 1.00 46.90  ? 60  GLU B C     1 
ATOM   3045 O O     . GLU B 1 60  ? 140.696 178.186 137.405 1.00 46.90  ? 60  GLU B O     1 
ATOM   3046 C CB    . GLU B 1 60  ? 142.410 179.588 135.604 1.00 46.90  ? 60  GLU B CB    1 
ATOM   3047 C CG    . GLU B 1 60  ? 143.213 179.649 136.898 1.00 46.90  ? 60  GLU B CG    1 
ATOM   3048 C CD    . GLU B 1 60  ? 144.670 179.286 136.698 1.00 46.90  ? 60  GLU B CD    1 
ATOM   3049 O OE1   . GLU B 1 60  ? 145.064 179.022 135.543 1.00 46.90  ? 60  GLU B OE1   1 
ATOM   3050 O OE2   . GLU B 1 60  ? 145.420 179.263 137.696 1.00 46.90  ? 60  GLU B OE2   1 
ATOM   3051 N N     . PRO B 1 61  ? 138.992 178.372 135.963 1.00 42.83  ? 61  PRO B N     1 
ATOM   3052 C CA    . PRO B 1 61  ? 138.338 177.179 136.510 1.00 42.83  ? 61  PRO B CA    1 
ATOM   3053 C C     . PRO B 1 61  ? 139.177 175.939 136.250 1.00 42.83  ? 61  PRO B C     1 
ATOM   3054 O O     . PRO B 1 61  ? 139.803 175.800 135.198 1.00 42.83  ? 61  PRO B O     1 
ATOM   3055 C CB    . PRO B 1 61  ? 137.006 177.125 135.754 1.00 42.83  ? 61  PRO B CB    1 
ATOM   3056 C CG    . PRO B 1 61  ? 136.779 178.524 135.290 1.00 42.83  ? 61  PRO B CG    1 
ATOM   3057 C CD    . PRO B 1 61  ? 138.140 179.069 134.987 1.00 42.83  ? 61  PRO B CD    1 
ATOM   3058 N N     . VAL B 1 62  ? 139.191 175.037 137.222 1.00 38.33  ? 62  VAL B N     1 
ATOM   3059 C CA    . VAL B 1 62  ? 139.905 173.771 137.106 1.00 38.33  ? 62  VAL B CA    1 
ATOM   3060 C C     . VAL B 1 62  ? 138.877 172.686 136.793 1.00 38.33  ? 62  VAL B C     1 
ATOM   3061 O O     . VAL B 1 62  ? 138.270 172.091 137.686 1.00 38.33  ? 62  VAL B O     1 
ATOM   3062 C CB    . VAL B 1 62  ? 140.740 173.475 138.356 1.00 38.33  ? 62  VAL B CB    1 
ATOM   3063 C CG1   . VAL B 1 62  ? 141.840 174.507 138.486 1.00 38.33  ? 62  VAL B CG1   1 
ATOM   3064 C CG2   . VAL B 1 62  ? 139.892 173.559 139.610 1.00 38.33  ? 62  VAL B CG2   1 
ATOM   3065 N N     . CYS B 1 63  ? 138.674 172.431 135.504 1.00 43.66  ? 63  CYS B N     1 
ATOM   3066 C CA    . CYS B 1 63  ? 137.759 171.390 135.072 1.00 43.66  ? 63  CYS B CA    1 
ATOM   3067 C C     . CYS B 1 63  ? 138.367 170.015 135.328 1.00 43.66  ? 63  CYS B C     1 
ATOM   3068 O O     . CYS B 1 63  ? 139.455 169.881 135.891 1.00 43.66  ? 63  CYS B O     1 
ATOM   3069 C CB    . CYS B 1 63  ? 137.414 171.563 133.596 1.00 43.66  ? 63  CYS B CB    1 
ATOM   3070 S SG    . CYS B 1 63  ? 136.964 173.255 133.150 1.00 43.66  ? 63  CYS B SG    1 
ATOM   3071 N N     . TYR B 1 64  ? 137.648 168.977 134.911 1.00 63.87  ? 64  TYR B N     1 
ATOM   3072 C CA    . TYR B 1 64  ? 138.085 167.607 135.148 1.00 63.87  ? 64  TYR B CA    1 
ATOM   3073 C C     . TYR B 1 64  ? 137.421 166.680 134.143 1.00 63.87  ? 64  TYR B C     1 
ATOM   3074 O O     . TYR B 1 64  ? 136.193 166.666 134.025 1.00 63.87  ? 64  TYR B O     1 
ATOM   3075 C CB    . TYR B 1 64  ? 137.761 167.171 136.580 1.00 63.87  ? 64  TYR B CB    1 
ATOM   3076 C CG    . TYR B 1 64  ? 137.604 165.680 136.760 1.00 63.87  ? 64  TYR B CG    1 
ATOM   3077 C CD1   . TYR B 1 64  ? 138.710 164.863 136.927 1.00 63.87  ? 64  TYR B CD1   1 
ATOM   3078 C CD2   . TYR B 1 64  ? 136.349 165.090 136.775 1.00 63.87  ? 64  TYR B CD2   1 
ATOM   3079 C CE1   . TYR B 1 64  ? 138.571 163.504 137.096 1.00 63.87  ? 64  TYR B CE1   1 
ATOM   3080 C CE2   . TYR B 1 64  ? 136.203 163.732 136.940 1.00 63.87  ? 64  TYR B CE2   1 
ATOM   3081 C CZ    . TYR B 1 64  ? 137.316 162.943 137.100 1.00 63.87  ? 64  TYR B CZ    1 
ATOM   3082 O OH    . TYR B 1 64  ? 137.171 161.586 137.266 1.00 63.87  ? 64  TYR B OH    1 
ATOM   3083 N N     . ASP B 1 65  ? 138.233 165.921 133.417 1.00 51.54  ? 65  ASP B N     1 
ATOM   3084 C CA    . ASP B 1 65  ? 137.768 164.810 132.603 1.00 51.54  ? 65  ASP B CA    1 
ATOM   3085 C C     . ASP B 1 65  ? 138.872 163.768 132.508 1.00 51.54  ? 65  ASP B C     1 
ATOM   3086 O O     . ASP B 1 65  ? 140.061 164.085 132.559 1.00 51.54  ? 65  ASP B O     1 
ATOM   3087 C CB    . ASP B 1 65  ? 137.297 165.276 131.213 1.00 51.54  ? 65  ASP B CB    1 
ATOM   3088 C CG    . ASP B 1 65  ? 138.402 165.913 130.384 1.00 51.54  ? 65  ASP B CG    1 
ATOM   3089 O OD1   . ASP B 1 65  ? 139.541 166.053 130.873 1.00 51.54  ? 65  ASP B OD1   1 
ATOM   3090 O OD2   . ASP B 1 65  ? 138.123 166.282 129.223 1.00 51.54  ? 65  ASP B OD2   1 
ATOM   3091 N N     . GLY B 1 66  ? 138.471 162.507 132.394 1.00 45.60  ? 66  GLY B N     1 
ATOM   3092 C CA    . GLY B 1 66  ? 139.430 161.424 132.481 1.00 45.60  ? 66  GLY B CA    1 
ATOM   3093 C C     . GLY B 1 66  ? 139.093 160.291 131.539 1.00 45.60  ? 66  GLY B C     1 
ATOM   3094 O O     . GLY B 1 66  ? 138.020 160.255 130.930 1.00 45.60  ? 66  GLY B O     1 
ATOM   3095 N N     . PHE B 1 67  ? 140.040 159.364 131.419 1.00 40.92  ? 67  PHE B N     1 
ATOM   3096 C CA    . PHE B 1 67  ? 139.885 158.205 130.556 1.00 40.92  ? 67  PHE B CA    1 
ATOM   3097 C C     . PHE B 1 67  ? 140.732 157.062 131.090 1.00 40.92  ? 67  PHE B C     1 
ATOM   3098 O O     . PHE B 1 67  ? 141.765 157.289 131.724 1.00 40.92  ? 67  PHE B O     1 
ATOM   3099 C CB    . PHE B 1 67  ? 140.291 158.525 129.114 1.00 40.92  ? 67  PHE B CB    1 
ATOM   3100 C CG    . PHE B 1 67  ? 141.753 158.822 128.945 1.00 40.92  ? 67  PHE B CG    1 
ATOM   3101 C CD1   . PHE B 1 67  ? 142.300 159.997 129.431 1.00 40.92  ? 67  PHE B CD1   1 
ATOM   3102 C CD2   . PHE B 1 67  ? 142.581 157.928 128.291 1.00 40.92  ? 67  PHE B CD2   1 
ATOM   3103 C CE1   . PHE B 1 67  ? 143.644 160.268 129.276 1.00 40.92  ? 67  PHE B CE1   1 
ATOM   3104 C CE2   . PHE B 1 67  ? 143.924 158.197 128.131 1.00 40.92  ? 67  PHE B CE2   1 
ATOM   3105 C CZ    . PHE B 1 67  ? 144.455 159.368 128.625 1.00 40.92  ? 67  PHE B CZ    1 
ATOM   3106 N N     . GLU B 1 68  ? 140.287 155.841 130.838 1.00 48.13  ? 68  GLU B N     1 
ATOM   3107 C CA    . GLU B 1 68  ? 141.075 154.674 131.214 1.00 48.13  ? 68  GLU B CA    1 
ATOM   3108 C C     . GLU B 1 68  ? 142.051 154.334 130.094 1.00 48.13  ? 68  GLU B C     1 
ATOM   3109 O O     . GLU B 1 68  ? 141.622 154.034 128.976 1.00 48.13  ? 68  GLU B O     1 
ATOM   3110 C CB    . GLU B 1 68  ? 140.170 153.482 131.502 1.00 48.13  ? 68  GLU B CB    1 
ATOM   3111 C CG    . GLU B 1 68  ? 139.317 153.639 132.748 1.00 48.13  ? 68  GLU B CG    1 
ATOM   3112 C CD    . GLU B 1 68  ? 138.337 152.500 132.921 1.00 48.13  ? 68  GLU B CD    1 
ATOM   3113 O OE1   . GLU B 1 68  ? 138.563 151.427 132.324 1.00 48.13  ? 68  GLU B OE1   1 
ATOM   3114 O OE2   . GLU B 1 68  ? 137.338 152.677 133.650 1.00 48.13  ? 68  GLU B OE2   1 
ATOM   3115 N N     . PRO B 1 69  ? 143.356 154.364 130.350 1.00 35.34  ? 69  PRO B N     1 
ATOM   3116 C CA    . PRO B 1 69  ? 144.346 154.132 129.279 1.00 35.34  ? 69  PRO B CA    1 
ATOM   3117 C C     . PRO B 1 69  ? 144.397 152.674 128.853 1.00 35.34  ? 69  PRO B C     1 
ATOM   3118 O O     . PRO B 1 69  ? 145.284 151.898 129.224 1.00 35.34  ? 69  PRO B O     1 
ATOM   3119 C CB    . PRO B 1 69  ? 145.646 154.605 129.937 1.00 35.34  ? 69  PRO B CB    1 
ATOM   3120 C CG    . PRO B 1 69  ? 145.453 154.298 131.368 1.00 35.34  ? 69  PRO B CG    1 
ATOM   3121 C CD    . PRO B 1 69  ? 143.998 154.549 131.661 1.00 35.34  ? 69  PRO B CD    1 
ATOM   3122 N N     . SER B 1 70  ? 143.419 152.273 128.047 1.00 39.25  ? 70  SER B N     1 
ATOM   3123 C CA    . SER B 1 70  ? 143.320 150.896 127.595 1.00 39.25  ? 70  SER B CA    1 
ATOM   3124 C C     . SER B 1 70  ? 142.623 150.842 126.247 1.00 39.25  ? 70  SER B C     1 
ATOM   3125 O O     . SER B 1 70  ? 141.851 151.735 125.891 1.00 39.25  ? 70  SER B O     1 
ATOM   3126 C CB    . SER B 1 70  ? 142.558 150.038 128.604 1.00 39.25  ? 70  SER B CB    1 
ATOM   3127 O OG    . SER B 1 70  ? 141.205 150.445 128.694 1.00 39.25  ? 70  SER B OG    1 
ATOM   3128 N N     . GLY B 1 71  ? 142.906 149.778 125.500 1.00 39.20  ? 71  GLY B N     1 
ATOM   3129 C CA    . GLY B 1 71  ? 142.250 149.549 124.232 1.00 39.20  ? 71  GLY B CA    1 
ATOM   3130 C C     . GLY B 1 71  ? 142.605 150.597 123.198 1.00 39.20  ? 71  GLY B C     1 
ATOM   3131 O O     . GLY B 1 71  ? 143.550 151.375 123.335 1.00 39.20  ? 71  GLY B O     1 
ATOM   3132 N N     . ARG B 1 72  ? 141.810 150.613 122.134 1.00 43.78  ? 72  ARG B N     1 
ATOM   3133 C CA    . ARG B 1 72  ? 141.934 151.639 121.115 1.00 43.78  ? 72  ARG B CA    1 
ATOM   3134 C C     . ARG B 1 72  ? 141.262 152.920 121.607 1.00 43.78  ? 72  ARG B C     1 
ATOM   3135 O O     . ARG B 1 72  ? 140.743 152.989 122.724 1.00 43.78  ? 72  ARG B O     1 
ATOM   3136 C CB    . ARG B 1 72  ? 141.338 151.145 119.800 1.00 43.78  ? 72  ARG B CB    1 
ATOM   3137 C CG    . ARG B 1 72  ? 141.709 149.704 119.474 1.00 43.78  ? 72  ARG B CG    1 
ATOM   3138 C CD    . ARG B 1 72  ? 141.147 149.256 118.136 1.00 43.78  ? 72  ARG B CD    1 
ATOM   3139 N NE    . ARG B 1 72  ? 141.669 150.055 117.035 1.00 43.78  ? 72  ARG B NE    1 
ATOM   3140 C CZ    . ARG B 1 72  ? 141.348 149.877 115.761 1.00 43.78  ? 72  ARG B CZ    1 
ATOM   3141 N NH1   . ARG B 1 72  ? 140.502 148.932 115.387 1.00 43.78  ? 72  ARG B NH1   1 
ATOM   3142 N NH2   . ARG B 1 72  ? 141.891 150.667 114.839 1.00 43.78  ? 72  ARG B NH2   1 
ATOM   3143 N N     . MET B 1 73  ? 141.277 153.955 120.774 1.00 34.82  ? 73  MET B N     1 
ATOM   3144 C CA    . MET B 1 73  ? 140.718 155.256 121.129 1.00 34.82  ? 73  MET B CA    1 
ATOM   3145 C C     . MET B 1 73  ? 139.825 155.745 119.995 1.00 34.82  ? 73  MET B C     1 
ATOM   3146 O O     . MET B 1 73  ? 140.315 156.103 118.920 1.00 34.82  ? 73  MET B O     1 
ATOM   3147 C CB    . MET B 1 73  ? 141.826 156.257 121.434 1.00 34.82  ? 73  MET B CB    1 
ATOM   3148 C CG    . MET B 1 73  ? 141.337 157.542 122.065 1.00 34.82  ? 73  MET B CG    1 
ATOM   3149 S SD    . MET B 1 73  ? 142.493 158.865 121.717 1.00 34.82  ? 73  MET B SD    1 
ATOM   3150 C CE    . MET B 1 73  ? 142.694 158.581 119.967 1.00 34.82  ? 73  MET B CE    1 
ATOM   3151 N N     . HIS B 1 74  ? 138.521 155.765 120.247 1.00 43.46  ? 74  HIS B N     1 
ATOM   3152 C CA    . HIS B 1 74  ? 137.547 156.149 119.237 1.00 43.46  ? 74  HIS B CA    1 
ATOM   3153 C C     . HIS B 1 74  ? 137.610 157.643 118.928 1.00 43.46  ? 74  HIS B C     1 
ATOM   3154 O O     . HIS B 1 74  ? 138.085 158.455 119.732 1.00 43.46  ? 74  HIS B O     1 
ATOM   3155 C CB    . HIS B 1 74  ? 136.143 155.754 119.693 1.00 43.46  ? 74  HIS B CB    1 
ATOM   3156 C CG    . HIS B 1 74  ? 135.807 156.207 121.079 1.00 43.46  ? 74  HIS B CG    1 
ATOM   3157 N ND1   . HIS B 1 74  ? 134.898 157.209 121.337 1.00 43.46  ? 74  HIS B ND1   1 
ATOM   3158 C CD2   . HIS B 1 74  ? 136.247 155.782 122.287 1.00 43.46  ? 74  HIS B CD2   1 
ATOM   3159 C CE1   . HIS B 1 74  ? 134.797 157.387 122.642 1.00 43.46  ? 74  HIS B CE1   1 
ATOM   3160 N NE2   . HIS B 1 74  ? 135.607 156.534 123.242 1.00 43.46  ? 74  HIS B NE2   1 
ATOM   3161 N N     . ILE B 1 75  ? 137.128 157.993 117.730 1.00 32.59  ? 75  ILE B N     1 
ATOM   3162 C CA    . ILE B 1 75  ? 137.176 159.379 117.276 1.00 32.59  ? 75  ILE B CA    1 
ATOM   3163 C C     . ILE B 1 75  ? 136.386 160.275 118.217 1.00 32.59  ? 75  ILE B C     1 
ATOM   3164 O O     . ILE B 1 75  ? 136.794 161.406 118.495 1.00 32.59  ? 75  ILE B O     1 
ATOM   3165 C CB    . ILE B 1 75  ? 136.677 159.497 115.822 1.00 32.59  ? 75  ILE B CB    1 
ATOM   3166 C CG1   . ILE B 1 75  ? 136.853 160.925 115.302 1.00 32.59  ? 75  ILE B CG1   1 
ATOM   3167 C CG2   . ILE B 1 75  ? 135.225 159.073 115.702 1.00 32.59  ? 75  ILE B CG2   1 
ATOM   3168 C CD1   . ILE B 1 75  ? 138.277 161.301 114.998 1.00 32.59  ? 75  ILE B CD1   1 
ATOM   3169 N N     . ALA B 1 76  ? 135.253 159.786 118.728 1.00 45.05  ? 76  ALA B N     1 
ATOM   3170 C CA    . ALA B 1 76  ? 134.493 160.569 119.697 1.00 45.05  ? 76  ALA B CA    1 
ATOM   3171 C C     . ALA B 1 76  ? 135.397 161.042 120.823 1.00 45.05  ? 76  ALA B C     1 
ATOM   3172 O O     . ALA B 1 76  ? 135.646 162.244 120.969 1.00 45.05  ? 76  ALA B O     1 
ATOM   3173 C CB    . ALA B 1 76  ? 133.332 159.746 120.253 1.00 45.05  ? 76  ALA B CB    1 
ATOM   3174 N N     . GLN B 1 77  ? 135.957 160.096 121.580 1.00 39.47  ? 77  GLN B N     1 
ATOM   3175 C CA    . GLN B 1 77  ? 136.898 160.441 122.638 1.00 39.47  ? 77  GLN B CA    1 
ATOM   3176 C C     . GLN B 1 77  ? 137.958 161.408 122.138 1.00 39.47  ? 77  GLN B C     1 
ATOM   3177 O O     . GLN B 1 77  ? 138.044 162.541 122.623 1.00 39.47  ? 77  GLN B O     1 
ATOM   3178 C CB    . GLN B 1 77  ? 137.554 159.174 123.180 1.00 39.47  ? 77  GLN B CB    1 
ATOM   3179 C CG    . GLN B 1 77  ? 138.660 159.416 124.181 1.00 39.47  ? 77  GLN B CG    1 
ATOM   3180 C CD    . GLN B 1 77  ? 139.030 158.161 124.939 1.00 39.47  ? 77  GLN B CD    1 
ATOM   3181 O OE1   . GLN B 1 77  ? 138.652 157.054 124.554 1.00 39.47  ? 77  GLN B OE1   1 
ATOM   3182 N NE2   . GLN B 1 77  ? 139.792 158.323 126.008 1.00 39.47  ? 77  GLN B NE2   1 
ATOM   3183 N N     . GLY B 1 78  ? 138.712 161.010 121.113 1.00 33.74  ? 78  GLY B N     1 
ATOM   3184 C CA    . GLY B 1 78  ? 139.864 161.801 120.709 1.00 33.74  ? 78  GLY B CA    1 
ATOM   3185 C C     . GLY B 1 78  ? 139.508 163.226 120.330 1.00 33.74  ? 78  GLY B C     1 
ATOM   3186 O O     . GLY B 1 78  ? 139.902 164.181 121.010 1.00 33.74  ? 78  GLY B O     1 
ATOM   3187 N N     . VAL B 1 79  ? 138.742 163.393 119.253 1.00 32.68  ? 79  VAL B N     1 
ATOM   3188 C CA    . VAL B 1 79  ? 138.537 164.729 118.708 1.00 32.68  ? 79  VAL B CA    1 
ATOM   3189 C C     . VAL B 1 79  ? 137.581 165.539 119.581 1.00 32.68  ? 79  VAL B C     1 
ATOM   3190 O O     . VAL B 1 79  ? 137.756 166.751 119.733 1.00 32.68  ? 79  VAL B O     1 
ATOM   3191 C CB    . VAL B 1 79  ? 138.077 164.660 117.238 1.00 32.68  ? 79  VAL B CB    1 
ATOM   3192 C CG1   . VAL B 1 79  ? 136.723 164.041 117.114 1.00 32.68  ? 79  VAL B CG1   1 
ATOM   3193 C CG2   . VAL B 1 79  ? 138.076 166.042 116.619 1.00 32.68  ? 79  VAL B CG2   1 
ATOM   3194 N N     . MET B 1 80  ? 136.546 164.908 120.159 1.00 32.81  ? 80  MET B N     1 
ATOM   3195 C CA    . MET B 1 80  ? 135.670 165.666 121.046 1.00 32.81  ? 80  MET B CA    1 
ATOM   3196 C C     . MET B 1 80  ? 136.412 166.176 122.271 1.00 32.81  ? 80  MET B C     1 
ATOM   3197 O O     . MET B 1 80  ? 136.235 167.334 122.662 1.00 32.81  ? 80  MET B O     1 
ATOM   3198 C CB    . MET B 1 80  ? 134.461 164.836 121.470 1.00 32.81  ? 80  MET B CB    1 
ATOM   3199 C CG    . MET B 1 80  ? 133.289 164.966 120.531 1.00 32.81  ? 80  MET B CG    1 
ATOM   3200 S SD    . MET B 1 80  ? 131.816 164.114 121.108 1.00 32.81  ? 80  MET B SD    1 
ATOM   3201 C CE    . MET B 1 80  ? 131.354 163.248 119.619 1.00 32.81  ? 80  MET B CE    1 
ATOM   3202 N N     . LYS B 1 81  ? 137.238 165.338 122.905 1.00 33.77  ? 81  LYS B N     1 
ATOM   3203 C CA    . LYS B 1 81  ? 138.007 165.849 124.026 1.00 33.77  ? 81  LYS B CA    1 
ATOM   3204 C C     . LYS B 1 81  ? 139.020 166.896 123.596 1.00 33.77  ? 81  LYS B C     1 
ATOM   3205 O O     . LYS B 1 81  ? 139.239 167.854 124.343 1.00 33.77  ? 81  LYS B O     1 
ATOM   3206 C CB    . LYS B 1 81  ? 138.708 164.705 124.758 1.00 33.77  ? 81  LYS B CB    1 
ATOM   3207 C CG    . LYS B 1 81  ? 138.969 164.995 126.229 1.00 33.77  ? 81  LYS B CG    1 
ATOM   3208 C CD    . LYS B 1 81  ? 139.305 163.732 127.002 1.00 33.77  ? 81  LYS B CD    1 
ATOM   3209 C CE    . LYS B 1 81  ? 138.106 162.806 127.090 1.00 33.77  ? 81  LYS B CE    1 
ATOM   3210 N NZ    . LYS B 1 81  ? 136.985 163.433 127.840 1.00 33.77  ? 81  LYS B NZ    1 
ATOM   3211 N N     . THR B 1 82  ? 139.611 166.763 122.406 1.00 27.88  ? 82  THR B N     1 
ATOM   3212 C CA    . THR B 1 82  ? 140.512 167.796 121.911 1.00 27.88  ? 82  THR B CA    1 
ATOM   3213 C C     . THR B 1 82  ? 139.797 169.132 121.732 1.00 27.88  ? 82  THR B C     1 
ATOM   3214 O O     . THR B 1 82  ? 140.300 170.173 122.166 1.00 27.88  ? 82  THR B O     1 
ATOM   3215 C CB    . THR B 1 82  ? 141.140 167.358 120.587 1.00 27.88  ? 82  THR B CB    1 
ATOM   3216 O OG1   . THR B 1 82  ? 141.762 166.079 120.752 1.00 27.88  ? 82  THR B OG1   1 
ATOM   3217 C CG2   . THR B 1 82  ? 142.188 168.363 120.146 1.00 27.88  ? 82  THR B CG2   1 
ATOM   3218 N N     . ILE B 1 83  ? 138.614 169.112 121.115 1.00 30.39  ? 83  ILE B N     1 
ATOM   3219 C CA    . ILE B 1 83  ? 137.851 170.341 120.904 1.00 30.39  ? 83  ILE B CA    1 
ATOM   3220 C C     . ILE B 1 83  ? 137.413 170.931 122.237 1.00 30.39  ? 83  ILE B C     1 
ATOM   3221 O O     . ILE B 1 83  ? 137.490 172.146 122.453 1.00 30.39  ? 83  ILE B O     1 
ATOM   3222 C CB    . ILE B 1 83  ? 136.646 170.076 119.984 1.00 30.39  ? 83  ILE B CB    1 
ATOM   3223 C CG1   . ILE B 1 83  ? 137.116 169.633 118.601 1.00 30.39  ? 83  ILE B CG1   1 
ATOM   3224 C CG2   . ILE B 1 83  ? 135.776 171.312 119.874 1.00 30.39  ? 83  ILE B CG2   1 
ATOM   3225 C CD1   . ILE B 1 83  ? 136.006 169.109 117.726 1.00 30.39  ? 83  ILE B CD1   1 
ATOM   3226 N N     . SER B 1 84  ? 136.942 170.080 123.151 1.00 27.27  ? 84  SER B N     1 
ATOM   3227 C CA    . SER B 1 84  ? 136.487 170.560 124.449 1.00 27.27  ? 84  SER B CA    1 
ATOM   3228 C C     . SER B 1 84  ? 137.626 171.211 125.219 1.00 27.27  ? 84  SER B C     1 
ATOM   3229 O O     . SER B 1 84  ? 137.458 172.280 125.816 1.00 27.27  ? 84  SER B O     1 
ATOM   3230 C CB    . SER B 1 84  ? 135.887 169.405 125.250 1.00 27.27  ? 84  SER B CB    1 
ATOM   3231 O OG    . SER B 1 84  ? 134.806 168.810 124.555 1.00 27.27  ? 84  SER B OG    1 
ATOM   3232 N N     . VAL B 1 85  ? 138.804 170.586 125.202 1.00 25.50  ? 85  VAL B N     1 
ATOM   3233 C CA    . VAL B 1 85  ? 139.935 171.130 125.941 1.00 25.50  ? 85  VAL B CA    1 
ATOM   3234 C C     . VAL B 1 85  ? 140.446 172.407 125.288 1.00 25.50  ? 85  VAL B C     1 
ATOM   3235 O O     . VAL B 1 85  ? 140.840 173.353 125.978 1.00 25.50  ? 85  VAL B O     1 
ATOM   3236 C CB    . VAL B 1 85  ? 141.039 170.072 126.075 1.00 25.50  ? 85  VAL B CB    1 
ATOM   3237 C CG1   . VAL B 1 85  ? 142.325 170.717 126.547 1.00 25.50  ? 85  VAL B CG1   1 
ATOM   3238 C CG2   . VAL B 1 85  ? 140.595 168.988 127.041 1.00 25.50  ? 85  VAL B CG2   1 
ATOM   3239 N N     . ASN B 1 86  ? 140.460 172.461 123.954 1.00 29.87  ? 86  ASN B N     1 
ATOM   3240 C CA    . ASN B 1 86  ? 140.846 173.699 123.286 1.00 29.87  ? 86  ASN B CA    1 
ATOM   3241 C C     . ASN B 1 86  ? 139.887 174.830 123.635 1.00 29.87  ? 86  ASN B C     1 
ATOM   3242 O O     . ASN B 1 86  ? 140.319 175.955 123.911 1.00 29.87  ? 86  ASN B O     1 
ATOM   3243 C CB    . ASN B 1 86  ? 140.901 173.488 121.775 1.00 29.87  ? 86  ASN B CB    1 
ATOM   3244 C CG    . ASN B 1 86  ? 141.976 172.506 121.367 1.00 29.87  ? 86  ASN B CG    1 
ATOM   3245 O OD1   . ASN B 1 86  ? 142.997 172.374 122.040 1.00 29.87  ? 86  ASN B OD1   1 
ATOM   3246 N ND2   . ASN B 1 86  ? 141.750 171.807 120.262 1.00 29.87  ? 86  ASN B ND2   1 
ATOM   3247 N N     . LYS B 1 87  ? 138.583 174.544 123.642 1.00 31.18  ? 87  LYS B N     1 
ATOM   3248 C CA    . LYS B 1 87  ? 137.596 175.548 124.023 1.00 31.18  ? 87  LYS B CA    1 
ATOM   3249 C C     . LYS B 1 87  ? 137.816 176.010 125.457 1.00 31.18  ? 87  LYS B C     1 
ATOM   3250 O O     . LYS B 1 87  ? 137.771 177.209 125.752 1.00 31.18  ? 87  LYS B O     1 
ATOM   3251 C CB    . LYS B 1 87  ? 136.187 174.980 123.853 1.00 31.18  ? 87  LYS B CB    1 
ATOM   3252 C CG    . LYS B 1 87  ? 135.652 175.041 122.435 1.00 31.18  ? 87  LYS B CG    1 
ATOM   3253 C CD    . LYS B 1 87  ? 134.274 174.406 122.343 1.00 31.18  ? 87  LYS B CD    1 
ATOM   3254 C CE    . LYS B 1 87  ? 133.666 174.597 120.964 1.00 31.18  ? 87  LYS B CE    1 
ATOM   3255 N NZ    . LYS B 1 87  ? 133.507 176.037 120.622 1.00 31.18  ? 87  LYS B NZ    1 
ATOM   3256 N N     . LEU B 1 88  ? 138.065 175.064 126.364 1.00 35.52  ? 88  LEU B N     1 
ATOM   3257 C CA    . LEU B 1 88  ? 138.255 175.414 127.767 1.00 35.52  ? 88  LEU B CA    1 
ATOM   3258 C C     . LEU B 1 88  ? 139.518 176.245 127.970 1.00 35.52  ? 88  LEU B C     1 
ATOM   3259 O O     . LEU B 1 88  ? 139.513 177.211 128.742 1.00 35.52  ? 88  LEU B O     1 
ATOM   3260 C CB    . LEU B 1 88  ? 138.296 174.142 128.610 1.00 35.52  ? 88  LEU B CB    1 
ATOM   3261 C CG    . LEU B 1 88  ? 136.926 173.508 128.848 1.00 35.52  ? 88  LEU B CG    1 
ATOM   3262 C CD1   . LEU B 1 88  ? 137.041 172.290 129.738 1.00 35.52  ? 88  LEU B CD1   1 
ATOM   3263 C CD2   . LEU B 1 88  ? 135.974 174.520 129.454 1.00 35.52  ? 88  LEU B CD2   1 
ATOM   3264 N N     . THR B 1 89  ? 140.607 175.886 127.288 1.00 36.48  ? 89  THR B N     1 
ATOM   3265 C CA    . THR B 1 89  ? 141.848 176.644 127.414 1.00 36.48  ? 89  THR B CA    1 
ATOM   3266 C C     . THR B 1 89  ? 141.705 178.035 126.810 1.00 36.48  ? 89  THR B C     1 
ATOM   3267 O O     . THR B 1 89  ? 142.246 179.011 127.345 1.00 36.48  ? 89  THR B O     1 
ATOM   3268 C CB    . THR B 1 89  ? 142.997 175.878 126.757 1.00 36.48  ? 89  THR B CB    1 
ATOM   3269 O OG1   . THR B 1 89  ? 143.225 174.659 127.473 1.00 36.48  ? 89  THR B OG1   1 
ATOM   3270 C CG2   . THR B 1 89  ? 144.275 176.704 126.771 1.00 36.48  ? 89  THR B CG2   1 
ATOM   3271 N N     . SER B 1 90  ? 140.975 178.151 125.697 1.00 38.21  ? 90  SER B N     1 
ATOM   3272 C CA    . SER B 1 90  ? 140.667 179.471 125.159 1.00 38.21  ? 90  SER B CA    1 
ATOM   3273 C C     . SER B 1 90  ? 139.856 180.284 126.159 1.00 38.21  ? 90  SER B C     1 
ATOM   3274 O O     . SER B 1 90  ? 140.078 181.490 126.320 1.00 38.21  ? 90  SER B O     1 
ATOM   3275 C CB    . SER B 1 90  ? 139.917 179.338 123.835 1.00 38.21  ? 90  SER B CB    1 
ATOM   3276 O OG    . SER B 1 90  ? 138.649 178.737 124.029 1.00 38.21  ? 90  SER B OG    1 
ATOM   3277 N N     . ALA B 1 91  ? 138.908 179.637 126.839 1.00 37.08  ? 91  ALA B N     1 
ATOM   3278 C CA    . ALA B 1 91  ? 138.216 180.289 127.944 1.00 37.08  ? 91  ALA B CA    1 
ATOM   3279 C C     . ALA B 1 91  ? 139.155 180.512 129.121 1.00 37.08  ? 91  ALA B C     1 
ATOM   3280 O O     . ALA B 1 91  ? 138.912 181.385 129.963 1.00 37.08  ? 91  ALA B O     1 
ATOM   3281 C CB    . ALA B 1 91  ? 137.008 179.456 128.371 1.00 37.08  ? 91  ALA B CB    1 
ATOM   3282 N N     . GLY B 1 92  ? 140.233 179.737 129.197 1.00 41.88  ? 92  GLY B N     1 
ATOM   3283 C CA    . GLY B 1 92  ? 141.172 179.852 130.294 1.00 41.88  ? 92  GLY B CA    1 
ATOM   3284 C C     . GLY B 1 92  ? 140.857 178.909 131.434 1.00 41.88  ? 92  GLY B C     1 
ATOM   3285 O O     . GLY B 1 92  ? 140.744 179.336 132.586 1.00 41.88  ? 92  GLY B O     1 
ATOM   3286 N N     . CYS B 1 93  ? 140.711 177.622 131.127 1.00 41.49  ? 93  CYS B N     1 
ATOM   3287 C CA    . CYS B 1 93  ? 140.373 176.619 132.126 1.00 41.49  ? 93  CYS B CA    1 
ATOM   3288 C C     . CYS B 1 93  ? 141.546 175.672 132.322 1.00 41.49  ? 93  CYS B C     1 
ATOM   3289 O O     . CYS B 1 93  ? 142.080 175.124 131.354 1.00 41.49  ? 93  CYS B O     1 
ATOM   3290 C CB    . CYS B 1 93  ? 139.124 175.827 131.722 1.00 41.49  ? 93  CYS B CB    1 
ATOM   3291 S SG    . CYS B 1 93  ? 137.566 176.687 132.028 1.00 41.49  ? 93  CYS B SG    1 
ATOM   3292 N N     . ARG B 1 94  ? 141.938 175.481 133.581 1.00 41.61  ? 94  ARG B N     1 
ATOM   3293 C CA    . ARG B 1 94  ? 143.034 174.577 133.932 1.00 41.61  ? 94  ARG B CA    1 
ATOM   3294 C C     . ARG B 1 94  ? 142.507 173.144 134.013 1.00 41.61  ? 94  ARG B C     1 
ATOM   3295 O O     . ARG B 1 94  ? 142.228 172.601 135.083 1.00 41.61  ? 94  ARG B O     1 
ATOM   3296 C CB    . ARG B 1 94  ? 143.681 175.011 135.240 1.00 41.61  ? 94  ARG B CB    1 
ATOM   3297 C CG    . ARG B 1 94  ? 145.039 174.383 135.509 1.00 41.61  ? 94  ARG B CG    1 
ATOM   3298 C CD    . ARG B 1 94  ? 146.046 174.748 134.434 1.00 41.61  ? 94  ARG B CD    1 
ATOM   3299 N NE    . ARG B 1 94  ? 147.418 174.566 134.891 1.00 41.61  ? 94  ARG B NE    1 
ATOM   3300 C CZ    . ARG B 1 94  ? 148.154 175.517 135.450 1.00 41.61  ? 94  ARG B CZ    1 
ATOM   3301 N NH1   . ARG B 1 94  ? 147.680 176.737 135.637 1.00 41.61  ? 94  ARG B NH1   1 
ATOM   3302 N NH2   . ARG B 1 94  ? 149.397 175.235 135.831 1.00 41.61  ? 94  ARG B NH2   1 
ATOM   3303 N N     . VAL B 1 95  ? 142.371 172.530 132.835 1.00 48.73  ? 95  VAL B N     1 
ATOM   3304 C CA    . VAL B 1 95  ? 141.874 171.163 132.763 1.00 48.73  ? 95  VAL B CA    1 
ATOM   3305 C C     . VAL B 1 95  ? 142.858 170.219 133.440 1.00 48.73  ? 95  VAL B C     1 
ATOM   3306 O O     . VAL B 1 95  ? 144.074 170.291 133.220 1.00 48.73  ? 95  VAL B O     1 
ATOM   3307 C CB    . VAL B 1 95  ? 141.629 170.763 131.300 1.00 48.73  ? 95  VAL B CB    1 
ATOM   3308 C CG1   . VAL B 1 95  ? 141.192 169.313 131.207 1.00 48.73  ? 95  VAL B CG1   1 
ATOM   3309 C CG2   . VAL B 1 95  ? 140.593 171.672 130.675 1.00 48.73  ? 95  VAL B CG2   1 
ATOM   3310 N N     . LYS B 1 96  ? 142.330 169.327 134.284 1.00 63.87  ? 96  LYS B N     1 
ATOM   3311 C CA    . LYS B 1 96  ? 143.128 168.345 135.024 1.00 63.87  ? 96  LYS B CA    1 
ATOM   3312 C C     . LYS B 1 96  ? 142.682 166.956 134.576 1.00 63.87  ? 96  LYS B C     1 
ATOM   3313 O O     . LYS B 1 96  ? 141.774 166.365 135.162 1.00 63.87  ? 96  LYS B O     1 
ATOM   3314 C CB    . LYS B 1 96  ? 142.970 168.533 136.528 1.00 63.87  ? 96  LYS B CB    1 
ATOM   3315 C CG    . LYS B 1 96  ? 143.738 169.711 137.094 1.00 63.87  ? 96  LYS B CG    1 
ATOM   3316 C CD    . LYS B 1 96  ? 143.546 169.816 138.597 1.00 63.87  ? 96  LYS B CD    1 
ATOM   3317 C CE    . LYS B 1 96  ? 144.514 170.812 139.213 1.00 63.87  ? 96  LYS B CE    1 
ATOM   3318 N NZ    . LYS B 1 96  ? 144.351 170.899 140.690 1.00 63.87  ? 96  LYS B NZ    1 
ATOM   3319 N N     . ILE B 1 97  ? 143.332 166.432 133.535 1.00 46.40  ? 97  ILE B N     1 
ATOM   3320 C CA    . ILE B 1 97  ? 142.931 165.142 132.993 1.00 46.40  ? 97  ILE B CA    1 
ATOM   3321 C C     . ILE B 1 97  ? 143.389 164.021 133.917 1.00 46.40  ? 97  ILE B C     1 
ATOM   3322 O O     . ILE B 1 97  ? 144.543 163.983 134.363 1.00 46.40  ? 97  ILE B O     1 
ATOM   3323 C CB    . ILE B 1 97  ? 143.484 164.963 131.571 1.00 46.40  ? 97  ILE B CB    1 
ATOM   3324 C CG1   . ILE B 1 97  ? 142.966 166.081 130.667 1.00 46.40  ? 97  ILE B CG1   1 
ATOM   3325 C CG2   . ILE B 1 97  ? 143.072 163.616 131.011 1.00 46.40  ? 97  ILE B CG2   1 
ATOM   3326 C CD1   . ILE B 1 97  ? 143.628 166.129 129.313 1.00 46.40  ? 97  ILE B CD1   1 
ATOM   3327 N N     . TRP B 1 98  ? 142.475 163.097 134.206 1.00 63.87  ? 98  TRP B N     1 
ATOM   3328 C CA    . TRP B 1 98  ? 142.699 162.020 135.169 1.00 63.87  ? 98  TRP B CA    1 
ATOM   3329 C C     . TRP B 1 98  ? 142.861 160.710 134.407 1.00 63.87  ? 98  TRP B C     1 
ATOM   3330 O O     . TRP B 1 98  ? 141.880 160.129 133.937 1.00 63.87  ? 98  TRP B O     1 
ATOM   3331 C CB    . TRP B 1 98  ? 141.538 161.947 136.154 1.00 63.87  ? 98  TRP B CB    1 
ATOM   3332 C CG    . TRP B 1 98  ? 141.770 161.058 137.328 1.00 63.87  ? 98  TRP B CG    1 
ATOM   3333 C CD1   . TRP B 1 98  ? 141.164 159.864 137.581 1.00 63.87  ? 98  TRP B CD1   1 
ATOM   3334 C CD2   . TRP B 1 98  ? 142.657 161.299 138.424 1.00 63.87  ? 98  TRP B CD2   1 
ATOM   3335 N NE1   . TRP B 1 98  ? 141.626 159.340 138.763 1.00 63.87  ? 98  TRP B NE1   1 
ATOM   3336 C CE2   . TRP B 1 98  ? 142.544 160.203 139.300 1.00 63.87  ? 98  TRP B CE2   1 
ATOM   3337 C CE3   . TRP B 1 98  ? 143.540 162.331 138.748 1.00 63.87  ? 98  TRP B CE3   1 
ATOM   3338 C CZ2   . TRP B 1 98  ? 143.279 160.112 140.475 1.00 63.87  ? 98  TRP B CZ2   1 
ATOM   3339 C CZ3   . TRP B 1 98  ? 144.268 162.237 139.915 1.00 63.87  ? 98  TRP B CZ3   1 
ATOM   3340 C CH2   . TRP B 1 98  ? 144.134 161.136 140.764 1.00 63.87  ? 98  TRP B CH2   1 
ATOM   3341 N N     . ILE B 1 99  ? 144.099 160.236 134.290 1.00 42.08  ? 99  ILE B N     1 
ATOM   3342 C CA    . ILE B 1 99  ? 144.361 158.972 133.607 1.00 42.08  ? 99  ILE B CA    1 
ATOM   3343 C C     . ILE B 1 99  ? 144.240 157.842 134.628 1.00 42.08  ? 99  ILE B C     1 
ATOM   3344 O O     . ILE B 1 99  ? 145.024 157.760 135.576 1.00 42.08  ? 99  ILE B O     1 
ATOM   3345 C CB    . ILE B 1 99  ? 145.730 158.964 132.916 1.00 42.08  ? 99  ILE B CB    1 
ATOM   3346 C CG1   . ILE B 1 99  ? 145.917 160.180 131.997 1.00 42.08  ? 99  ILE B CG1   1 
ATOM   3347 C CG2   . ILE B 1 99  ? 145.894 157.708 132.095 1.00 42.08  ? 99  ILE B CG2   1 
ATOM   3348 C CD1   . ILE B 1 99  ? 146.407 161.452 132.654 1.00 42.08  ? 99  ILE B CD1   1 
ATOM   3349 N N     . ALA B 1 100 ? 143.265 156.955 134.419 1.00 38.49  ? 100 ALA B N     1 
ATOM   3350 C CA    . ALA B 1 100 ? 142.824 156.002 135.440 1.00 38.49  ? 100 ALA B CA    1 
ATOM   3351 C C     . ALA B 1 100 ? 143.552 154.664 135.290 1.00 38.49  ? 100 ALA B C     1 
ATOM   3352 O O     . ALA B 1 100 ? 142.991 153.643 134.876 1.00 38.49  ? 100 ALA B O     1 
ATOM   3353 C CB    . ALA B 1 100 ? 141.314 155.825 135.365 1.00 38.49  ? 100 ALA B CB    1 
ATOM   3354 N N     . ASP B 1 101 ? 144.835 154.675 135.666 1.00 38.49  ? 101 ASP B N     1 
ATOM   3355 C CA    . ASP B 1 101 ? 145.654 153.486 135.458 1.00 38.49  ? 101 ASP B CA    1 
ATOM   3356 C C     . ASP B 1 101 ? 145.349 152.388 136.477 1.00 38.49  ? 101 ASP B C     1 
ATOM   3357 O O     . ASP B 1 101 ? 145.360 151.204 136.125 1.00 38.49  ? 101 ASP B O     1 
ATOM   3358 C CB    . ASP B 1 101 ? 147.139 153.852 135.443 1.00 38.49  ? 101 ASP B CB    1 
ATOM   3359 C CG    . ASP B 1 101 ? 147.624 154.439 136.744 1.00 38.49  ? 101 ASP B CG    1 
ATOM   3360 O OD1   . ASP B 1 101 ? 146.852 154.504 137.723 1.00 38.49  ? 101 ASP B OD1   1 
ATOM   3361 O OD2   . ASP B 1 101 ? 148.804 154.844 136.774 1.00 38.49  ? 101 ASP B OD2   1 
ATOM   3362 N N     . TRP B 1 102 ? 145.056 152.741 137.737 1.00 40.05  ? 102 TRP B N     1 
ATOM   3363 C CA    . TRP B 1 102 ? 144.556 151.704 138.640 1.00 40.05  ? 102 TRP B CA    1 
ATOM   3364 C C     . TRP B 1 102 ? 143.218 151.147 138.187 1.00 40.05  ? 102 TRP B C     1 
ATOM   3365 O O     . TRP B 1 102 ? 142.975 149.947 138.326 1.00 40.05  ? 102 TRP B O     1 
ATOM   3366 C CB    . TRP B 1 102 ? 144.451 152.154 140.097 1.00 40.05  ? 102 TRP B CB    1 
ATOM   3367 C CG    . TRP B 1 102 ? 145.737 152.371 140.784 1.00 40.05  ? 102 TRP B CG    1 
ATOM   3368 C CD1   . TRP B 1 102 ? 146.981 152.095 140.308 1.00 40.05  ? 102 TRP B CD1   1 
ATOM   3369 C CD2   . TRP B 1 102 ? 145.897 152.693 142.165 1.00 40.05  ? 102 TRP B CD2   1 
ATOM   3370 N NE1   . TRP B 1 102 ? 147.921 152.338 141.278 1.00 40.05  ? 102 TRP B NE1   1 
ATOM   3371 C CE2   . TRP B 1 102 ? 147.277 152.697 142.434 1.00 40.05  ? 102 TRP B CE2   1 
ATOM   3372 C CE3   . TRP B 1 102 ? 145.006 153.028 143.189 1.00 40.05  ? 102 TRP B CE3   1 
ATOM   3373 C CZ2   . TRP B 1 102 ? 147.787 153.027 143.686 1.00 40.05  ? 102 TRP B CZ2   1 
ATOM   3374 C CZ3   . TRP B 1 102 ? 145.513 153.354 144.420 1.00 40.05  ? 102 TRP B CZ3   1 
ATOM   3375 C CH2   . TRP B 1 102 ? 146.886 153.350 144.661 1.00 40.05  ? 102 TRP B CH2   1 
ATOM   3376 N N     . PHE B 1 103 ? 142.320 151.988 137.683 1.00 39.06  ? 103 PHE B N     1 
ATOM   3377 C CA    . PHE B 1 103 ? 141.080 151.424 137.161 1.00 39.06  ? 103 PHE B CA    1 
ATOM   3378 C C     . PHE B 1 103 ? 141.312 150.475 135.994 1.00 39.06  ? 103 PHE B C     1 
ATOM   3379 O O     . PHE B 1 103 ? 140.662 149.424 135.939 1.00 39.06  ? 103 PHE B O     1 
ATOM   3380 C CB    . PHE B 1 103 ? 140.105 152.529 136.751 1.00 39.06  ? 103 PHE B CB    1 
ATOM   3381 C CG    . PHE B 1 103 ? 139.736 153.468 137.867 1.00 39.06  ? 103 PHE B CG    1 
ATOM   3382 C CD1   . PHE B 1 103 ? 140.650 154.370 138.390 1.00 39.06  ? 103 PHE B CD1   1 
ATOM   3383 C CD2   . PHE B 1 103 ? 138.454 153.454 138.382 1.00 39.06  ? 103 PHE B CD2   1 
ATOM   3384 C CE1   . PHE B 1 103 ? 140.294 155.230 139.413 1.00 39.06  ? 103 PHE B CE1   1 
ATOM   3385 C CE2   . PHE B 1 103 ? 138.091 154.309 139.399 1.00 39.06  ? 103 PHE B CE2   1 
ATOM   3386 C CZ    . PHE B 1 103 ? 139.012 155.200 139.916 1.00 39.06  ? 103 PHE B CZ    1 
ATOM   3387 N N     . ALA B 1 104 ? 142.236 150.797 135.088 1.00 49.09  ? 104 ALA B N     1 
ATOM   3388 C CA    . ALA B 1 104 ? 142.599 149.871 134.018 1.00 49.09  ? 104 ALA B CA    1 
ATOM   3389 C C     . ALA B 1 104 ? 143.175 148.568 134.576 1.00 49.09  ? 104 ALA B C     1 
ATOM   3390 O O     . ALA B 1 104 ? 142.780 147.475 134.157 1.00 49.09  ? 104 ALA B O     1 
ATOM   3391 C CB    . ALA B 1 104 ? 143.592 150.542 133.063 1.00 49.09  ? 104 ALA B CB    1 
ATOM   3392 N N     . LYS B 1 105 ? 144.088 148.668 135.542 1.00 41.90  ? 105 LYS B N     1 
ATOM   3393 C CA    . LYS B 1 105 ? 144.706 147.485 136.133 1.00 41.90  ? 105 LYS B CA    1 
ATOM   3394 C C     . LYS B 1 105 ? 143.670 146.601 136.816 1.00 41.90  ? 105 LYS B C     1 
ATOM   3395 O O     . LYS B 1 105 ? 143.699 145.373 136.679 1.00 41.90  ? 105 LYS B O     1 
ATOM   3396 C CB    . LYS B 1 105 ? 145.785 147.889 137.140 1.00 41.90  ? 105 LYS B CB    1 
ATOM   3397 C CG    . LYS B 1 105 ? 147.048 148.464 136.521 1.00 41.90  ? 105 LYS B CG    1 
ATOM   3398 C CD    . LYS B 1 105 ? 147.832 149.301 137.520 1.00 41.90  ? 105 LYS B CD    1 
ATOM   3399 C CE    . LYS B 1 105 ? 147.958 148.602 138.864 1.00 41.90  ? 105 LYS B CE    1 
ATOM   3400 N NZ    . LYS B 1 105 ? 148.574 147.252 138.745 1.00 41.90  ? 105 LYS B NZ    1 
ATOM   3401 N N     . LEU B 1 106 ? 142.754 147.223 137.559 1.00 40.71  ? 106 LEU B N     1 
ATOM   3402 C CA    . LEU B 1 106 ? 141.750 146.476 138.304 1.00 40.71  ? 106 LEU B CA    1 
ATOM   3403 C C     . LEU B 1 106 ? 140.702 145.869 137.382 1.00 40.71  ? 106 LEU B C     1 
ATOM   3404 O O     . LEU B 1 106 ? 140.160 144.799 137.684 1.00 40.71  ? 106 LEU B O     1 
ATOM   3405 C CB    . LEU B 1 106 ? 141.094 147.382 139.345 1.00 40.71  ? 106 LEU B CB    1 
ATOM   3406 C CG    . LEU B 1 106 ? 142.022 147.926 140.436 1.00 40.71  ? 106 LEU B CG    1 
ATOM   3407 C CD1   . LEU B 1 106 ? 141.227 148.601 141.538 1.00 40.71  ? 106 LEU B CD1   1 
ATOM   3408 C CD2   . LEU B 1 106 ? 142.912 146.834 141.002 1.00 40.71  ? 106 LEU B CD2   1 
ATOM   3409 N N     . ASN B 1 107 ? 140.398 146.524 136.264 1.00 45.68  ? 107 ASN B N     1 
ATOM   3410 C CA    . ASN B 1 107 ? 139.562 145.908 135.245 1.00 45.68  ? 107 ASN B CA    1 
ATOM   3411 C C     . ASN B 1 107 ? 140.350 144.947 134.367 1.00 45.68  ? 107 ASN B C     1 
ATOM   3412 O O     . ASN B 1 107 ? 139.775 144.345 133.453 1.00 45.68  ? 107 ASN B O     1 
ATOM   3413 C CB    . ASN B 1 107 ? 138.900 146.986 134.384 1.00 45.68  ? 107 ASN B CB    1 
ATOM   3414 C CG    . ASN B 1 107 ? 137.489 146.617 133.979 1.00 45.68  ? 107 ASN B CG    1 
ATOM   3415 O OD1   . ASN B 1 107 ? 136.965 145.581 134.387 1.00 45.68  ? 107 ASN B OD1   1 
ATOM   3416 N ND2   . ASN B 1 107 ? 136.866 147.464 133.168 1.00 45.68  ? 107 ASN B ND2   1 
ATOM   3417 N N     . ASN B 1 108 ? 141.653 144.820 134.628 1.00 61.19  ? 108 ASN B N     1 
ATOM   3418 C CA    . ASN B 1 108 ? 142.528 143.859 133.957 1.00 61.19  ? 108 ASN B CA    1 
ATOM   3419 C C     . ASN B 1 108 ? 142.654 144.193 132.472 1.00 61.19  ? 108 ASN B C     1 
ATOM   3420 O O     . ASN B 1 108 ? 142.291 143.417 131.586 1.00 61.19  ? 108 ASN B O     1 
ATOM   3421 C CB    . ASN B 1 108 ? 142.043 142.422 134.170 1.00 61.19  ? 108 ASN B CB    1 
ATOM   3422 C CG    . ASN B 1 108 ? 143.040 141.395 133.679 1.00 61.19  ? 108 ASN B CG    1 
ATOM   3423 O OD1   . ASN B 1 108 ? 144.249 141.622 133.716 1.00 61.19  ? 108 ASN B OD1   1 
ATOM   3424 N ND2   . ASN B 1 108 ? 142.538 140.257 133.215 1.00 61.19  ? 108 ASN B ND2   1 
ATOM   3425 N N     . LYS B 1 109 ? 143.178 145.388 132.223 1.00 60.34  ? 109 LYS B N     1 
ATOM   3426 C CA    . LYS B 1 109 ? 143.402 145.898 130.879 1.00 60.34  ? 109 LYS B CA    1 
ATOM   3427 C C     . LYS B 1 109 ? 144.856 145.650 130.498 1.00 60.34  ? 109 LYS B C     1 
ATOM   3428 O O     . LYS B 1 109 ? 145.760 145.877 131.310 1.00 60.34  ? 109 LYS B O     1 
ATOM   3429 C CB    . LYS B 1 109 ? 143.067 147.386 130.813 1.00 60.34  ? 109 LYS B CB    1 
ATOM   3430 C CG    . LYS B 1 109 ? 141.599 147.696 131.056 1.00 60.34  ? 109 LYS B CG    1 
ATOM   3431 C CD    . LYS B 1 109 ? 140.695 146.739 130.297 1.00 60.34  ? 109 LYS B CD    1 
ATOM   3432 C CE    . LYS B 1 109 ? 139.230 147.000 130.607 1.00 60.34  ? 109 LYS B CE    1 
ATOM   3433 N NZ    . LYS B 1 109 ? 138.361 145.874 130.169 1.00 60.34  ? 109 LYS B NZ    1 
ATOM   3434 N N     . MET B 1 110 ? 145.074 145.182 129.267 1.00 73.98  ? 110 MET B N     1 
ATOM   3435 C CA    . MET B 1 110 ? 146.404 144.821 128.775 1.00 73.98  ? 110 MET B CA    1 
ATOM   3436 C C     . MET B 1 110 ? 147.060 143.771 129.672 1.00 73.98  ? 110 MET B C     1 
ATOM   3437 O O     . MET B 1 110 ? 148.258 143.831 129.949 1.00 73.98  ? 110 MET B O     1 
ATOM   3438 C CB    . MET B 1 110 ? 147.305 146.052 128.635 1.00 73.98  ? 110 MET B CB    1 
ATOM   3439 C CG    . MET B 1 110 ? 146.847 147.054 127.584 1.00 73.98  ? 110 MET B CG    1 
ATOM   3440 S SD    . MET B 1 110 ? 146.800 146.386 125.908 1.00 73.98  ? 110 MET B SD    1 
ATOM   3441 C CE    . MET B 1 110 ? 145.044 146.097 125.695 1.00 73.98  ? 110 MET B CE    1 
ATOM   3442 N N     . GLY B 1 111 ? 146.266 142.806 130.131 1.00 77.45  ? 111 GLY B N     1 
ATOM   3443 C CA    . GLY B 1 111 ? 146.782 141.753 130.982 1.00 77.45  ? 111 GLY B CA    1 
ATOM   3444 C C     . GLY B 1 111 ? 147.168 142.191 132.374 1.00 77.45  ? 111 GLY B C     1 
ATOM   3445 O O     . GLY B 1 111 ? 147.955 141.505 133.031 1.00 77.45  ? 111 GLY B O     1 
ATOM   3446 N N     . GLY B 1 112 ? 146.633 143.313 132.848 1.00 73.08  ? 112 GLY B N     1 
ATOM   3447 C CA    . GLY B 1 112 ? 146.960 143.790 134.178 1.00 73.08  ? 112 GLY B CA    1 
ATOM   3448 C C     . GLY B 1 112 ? 148.410 144.170 134.368 1.00 73.08  ? 112 GLY B C     1 
ATOM   3449 O O     . GLY B 1 112 ? 148.963 143.954 135.450 1.00 73.08  ? 112 GLY B O     1 
ATOM   3450 N N     . ASP B 1 113 ? 149.044 144.730 133.343 1.00 66.17  ? 113 ASP B N     1 
ATOM   3451 C CA    . ASP B 1 113 ? 150.443 145.126 133.408 1.00 66.17  ? 113 ASP B CA    1 
ATOM   3452 C C     . ASP B 1 113 ? 150.535 146.642 133.518 1.00 66.17  ? 113 ASP B C     1 
ATOM   3453 O O     . ASP B 1 113 ? 150.049 147.363 132.640 1.00 66.17  ? 113 ASP B O     1 
ATOM   3454 C CB    . ASP B 1 113 ? 151.207 144.635 132.177 1.00 66.17  ? 113 ASP B CB    1 
ATOM   3455 C CG    . ASP B 1 113 ? 152.710 144.625 132.387 1.00 66.17  ? 113 ASP B CG    1 
ATOM   3456 O OD1   . ASP B 1 113 ? 153.168 145.081 133.455 1.00 66.17  ? 113 ASP B OD1   1 
ATOM   3457 O OD2   . ASP B 1 113 ? 153.434 144.157 131.483 1.00 66.17  ? 113 ASP B OD2   1 
ATOM   3458 N N     . LEU B 1 114 ? 151.158 147.117 134.599 1.00 57.04  ? 114 LEU B N     1 
ATOM   3459 C CA    . LEU B 1 114 ? 151.278 148.555 134.811 1.00 57.04  ? 114 LEU B CA    1 
ATOM   3460 C C     . LEU B 1 114 ? 152.104 149.212 133.713 1.00 57.04  ? 114 LEU B C     1 
ATOM   3461 O O     . LEU B 1 114 ? 151.754 150.294 133.231 1.00 57.04  ? 114 LEU B O     1 
ATOM   3462 C CB    . LEU B 1 114 ? 151.890 148.837 136.182 1.00 57.04  ? 114 LEU B CB    1 
ATOM   3463 C CG    . LEU B 1 114 ? 152.252 150.296 136.468 1.00 57.04  ? 114 LEU B CG    1 
ATOM   3464 C CD1   . LEU B 1 114 ? 151.000 151.145 136.595 1.00 57.04  ? 114 LEU B CD1   1 
ATOM   3465 C CD2   . LEU B 1 114 ? 153.107 150.403 137.720 1.00 57.04  ? 114 LEU B CD2   1 
ATOM   3466 N N     . LYS B 1 115 ? 153.205 148.575 133.305 1.00 58.04  ? 115 LYS B N     1 
ATOM   3467 C CA    . LYS B 1 115 ? 154.041 149.152 132.257 1.00 58.04  ? 115 LYS B CA    1 
ATOM   3468 C C     . LYS B 1 115 ? 153.311 149.193 130.920 1.00 58.04  ? 115 LYS B C     1 
ATOM   3469 O O     . LYS B 1 115 ? 153.398 150.188 130.191 1.00 58.04  ? 115 LYS B O     1 
ATOM   3470 C CB    . LYS B 1 115 ? 155.347 148.368 132.137 1.00 58.04  ? 115 LYS B CB    1 
ATOM   3471 C CG    . LYS B 1 115 ? 156.280 148.554 133.321 1.00 58.04  ? 115 LYS B CG    1 
ATOM   3472 C CD    . LYS B 1 115 ? 156.775 149.989 133.407 1.00 58.04  ? 115 LYS B CD    1 
ATOM   3473 C CE    . LYS B 1 115 ? 157.674 150.194 134.615 1.00 58.04  ? 115 LYS B CE    1 
ATOM   3474 N NZ    . LYS B 1 115 ? 158.171 151.594 134.703 1.00 58.04  ? 115 LYS B NZ    1 
ATOM   3475 N N     . LYS B 1 116 ? 152.582 148.126 130.581 1.00 55.48  ? 116 LYS B N     1 
ATOM   3476 C CA    . LYS B 1 116 ? 151.811 148.124 129.341 1.00 55.48  ? 116 LYS B CA    1 
ATOM   3477 C C     . LYS B 1 116 ? 150.724 149.192 129.364 1.00 55.48  ? 116 LYS B C     1 
ATOM   3478 O O     . LYS B 1 116 ? 150.481 149.867 128.356 1.00 55.48  ? 116 LYS B O     1 
ATOM   3479 C CB    . LYS B 1 116 ? 151.199 146.745 129.103 1.00 55.48  ? 116 LYS B CB    1 
ATOM   3480 C CG    . LYS B 1 116 ? 152.213 145.651 128.820 1.00 55.48  ? 116 LYS B CG    1 
ATOM   3481 C CD    . LYS B 1 116 ? 151.536 144.418 128.244 1.00 55.48  ? 116 LYS B CD    1 
ATOM   3482 C CE    . LYS B 1 116 ? 152.471 143.221 128.240 1.00 55.48  ? 116 LYS B CE    1 
ATOM   3483 N NZ    . LYS B 1 116 ? 151.763 141.972 127.845 1.00 55.48  ? 116 LYS B NZ    1 
ATOM   3484 N N     . ILE B 1 117 ? 150.055 149.356 130.506 1.00 46.03  ? 117 ILE B N     1 
ATOM   3485 C CA    . ILE B 1 117 ? 149.004 150.360 130.610 1.00 46.03  ? 117 ILE B CA    1 
ATOM   3486 C C     . ILE B 1 117 ? 149.590 151.763 130.507 1.00 46.03  ? 117 ILE B C     1 
ATOM   3487 O O     . ILE B 1 117 ? 149.008 152.646 129.867 1.00 46.03  ? 117 ILE B O     1 
ATOM   3488 C CB    . ILE B 1 117 ? 148.211 150.153 131.912 1.00 46.03  ? 117 ILE B CB    1 
ATOM   3489 C CG1   . ILE B 1 117 ? 147.231 148.994 131.732 1.00 46.03  ? 117 ILE B CG1   1 
ATOM   3490 C CG2   . ILE B 1 117 ? 147.477 151.416 132.308 1.00 46.03  ? 117 ILE B CG2   1 
ATOM   3491 C CD1   . ILE B 1 117 ? 146.565 148.557 133.002 1.00 46.03  ? 117 ILE B CD1   1 
ATOM   3492 N N     . GLU B 1 118 ? 150.755 151.989 131.116 1.00 48.77  ? 118 GLU B N     1 
ATOM   3493 C CA    . GLU B 1 118 ? 151.423 153.278 130.969 1.00 48.77  ? 118 GLU B CA    1 
ATOM   3494 C C     . GLU B 1 118 ? 151.820 153.529 129.519 1.00 48.77  ? 118 GLU B C     1 
ATOM   3495 O O     . GLU B 1 118 ? 151.720 154.658 129.027 1.00 48.77  ? 118 GLU B O     1 
ATOM   3496 C CB    . GLU B 1 118 ? 152.649 153.345 131.876 1.00 48.77  ? 118 GLU B CB    1 
ATOM   3497 C CG    . GLU B 1 118 ? 153.462 154.616 131.705 1.00 48.77  ? 118 GLU B CG    1 
ATOM   3498 C CD    . GLU B 1 118 ? 154.872 154.482 132.235 1.00 48.77  ? 118 GLU B CD    1 
ATOM   3499 O OE1   . GLU B 1 118 ? 155.251 153.366 132.648 1.00 48.77  ? 118 GLU B OE1   1 
ATOM   3500 O OE2   . GLU B 1 118 ? 155.606 155.493 132.231 1.00 48.77  ? 118 GLU B OE2   1 
ATOM   3501 N N     . THR B 1 119 ? 152.285 152.489 128.823 1.00 43.87  ? 119 THR B N     1 
ATOM   3502 C CA    . THR B 1 119 ? 152.631 152.640 127.412 1.00 43.87  ? 119 THR B CA    1 
ATOM   3503 C C     . THR B 1 119 ? 151.409 153.012 126.581 1.00 43.87  ? 119 THR B C     1 
ATOM   3504 O O     . THR B 1 119 ? 151.479 153.898 125.722 1.00 43.87  ? 119 THR B O     1 
ATOM   3505 C CB    . THR B 1 119 ? 153.266 151.352 126.889 1.00 43.87  ? 119 THR B CB    1 
ATOM   3506 O OG1   . THR B 1 119 ? 154.579 151.205 127.443 1.00 43.87  ? 119 THR B OG1   1 
ATOM   3507 C CG2   . THR B 1 119 ? 153.361 151.376 125.372 1.00 43.87  ? 119 THR B CG2   1 
ATOM   3508 N N     . VAL B 1 120 ? 150.275 152.354 126.833 1.00 33.64  ? 120 VAL B N     1 
ATOM   3509 C CA    . VAL B 1 120 ? 149.050 152.675 126.103 1.00 33.64  ? 120 VAL B CA    1 
ATOM   3510 C C     . VAL B 1 120 ? 148.606 154.101 126.409 1.00 33.64  ? 120 VAL B C     1 
ATOM   3511 O O     . VAL B 1 120 ? 148.156 154.836 125.519 1.00 33.64  ? 120 VAL B O     1 
ATOM   3512 C CB    . VAL B 1 120 ? 147.946 151.653 126.431 1.00 33.64  ? 120 VAL B CB    1 
ATOM   3513 C CG1   . VAL B 1 120 ? 146.618 152.092 125.843 1.00 33.64  ? 120 VAL B CG1   1 
ATOM   3514 C CG2   . VAL B 1 120 ? 148.329 150.278 125.913 1.00 33.64  ? 120 VAL B CG2   1 
ATOM   3515 N N     . GLY B 1 121 ? 148.725 154.513 127.671 1.00 32.98  ? 121 GLY B N     1 
ATOM   3516 C CA    . GLY B 1 121 ? 148.382 155.879 128.027 1.00 32.98  ? 121 GLY B CA    1 
ATOM   3517 C C     . GLY B 1 121 ? 149.255 156.900 127.325 1.00 32.98  ? 121 GLY B C     1 
ATOM   3518 O O     . GLY B 1 121 ? 148.761 157.912 126.825 1.00 32.98  ? 121 GLY B O     1 
ATOM   3519 N N     . ARG B 1 122 ? 150.564 156.649 127.278 1.00 33.56  ? 122 ARG B N     1 
ATOM   3520 C CA    . ARG B 1 122 ? 151.460 157.545 126.557 1.00 33.56  ? 122 ARG B CA    1 
ATOM   3521 C C     . ARG B 1 122 ? 151.134 157.577 125.072 1.00 33.56  ? 122 ARG B C     1 
ATOM   3522 O O     . ARG B 1 122 ? 151.211 158.635 124.442 1.00 33.56  ? 122 ARG B O     1 
ATOM   3523 C CB    . ARG B 1 122 ? 152.913 157.126 126.774 1.00 33.56  ? 122 ARG B CB    1 
ATOM   3524 C CG    . ARG B 1 122 ? 153.416 157.340 128.189 1.00 33.56  ? 122 ARG B CG    1 
ATOM   3525 C CD    . ARG B 1 122 ? 154.850 157.838 128.185 1.00 33.56  ? 122 ARG B CD    1 
ATOM   3526 N NE    . ARG B 1 122 ? 155.086 158.796 127.112 1.00 33.56  ? 122 ARG B NE    1 
ATOM   3527 C CZ    . ARG B 1 122 ? 156.239 158.937 126.473 1.00 33.56  ? 122 ARG B CZ    1 
ATOM   3528 N NH1   . ARG B 1 122 ? 157.288 158.187 126.768 1.00 33.56  ? 122 ARG B NH1   1 
ATOM   3529 N NH2   . ARG B 1 122 ? 156.341 159.850 125.512 1.00 33.56  ? 122 ARG B NH2   1 
ATOM   3530 N N     . TYR B 1 123 ? 150.767 156.430 124.503 1.00 36.84  ? 123 TYR B N     1 
ATOM   3531 C CA    . TYR B 1 123 ? 150.330 156.376 123.111 1.00 36.84  ? 123 TYR B CA    1 
ATOM   3532 C C     . TYR B 1 123 ? 149.122 157.275 122.878 1.00 36.84  ? 123 TYR B C     1 
ATOM   3533 O O     . TYR B 1 123 ? 149.088 158.061 121.921 1.00 36.84  ? 123 TYR B O     1 
ATOM   3534 C CB    . TYR B 1 123 ? 150.015 154.923 122.755 1.00 36.84  ? 123 TYR B CB    1 
ATOM   3535 C CG    . TYR B 1 123 ? 149.139 154.701 121.547 1.00 36.84  ? 123 TYR B CG    1 
ATOM   3536 C CD1   . TYR B 1 123 ? 149.580 155.019 120.275 1.00 36.84  ? 123 TYR B CD1   1 
ATOM   3537 C CD2   . TYR B 1 123 ? 147.880 154.132 121.682 1.00 36.84  ? 123 TYR B CD2   1 
ATOM   3538 C CE1   . TYR B 1 123 ? 148.784 154.798 119.173 1.00 36.84  ? 123 TYR B CE1   1 
ATOM   3539 C CE2   . TYR B 1 123 ? 147.079 153.908 120.587 1.00 36.84  ? 123 TYR B CE2   1 
ATOM   3540 C CZ    . TYR B 1 123 ? 147.536 154.240 119.334 1.00 36.84  ? 123 TYR B CZ    1 
ATOM   3541 O OH    . TYR B 1 123 ? 146.739 154.022 118.236 1.00 36.84  ? 123 TYR B OH    1 
ATOM   3542 N N     . LEU B 1 124 ? 148.123 157.182 123.758 1.00 30.76  ? 124 LEU B N     1 
ATOM   3543 C CA    . LEU B 1 124 ? 146.926 158.003 123.605 1.00 30.76  ? 124 LEU B CA    1 
ATOM   3544 C C     . LEU B 1 124 ? 147.249 159.483 123.762 1.00 30.76  ? 124 LEU B C     1 
ATOM   3545 O O     . LEU B 1 124 ? 146.732 160.327 123.018 1.00 30.76  ? 124 LEU B O     1 
ATOM   3546 C CB    . LEU B 1 124 ? 145.864 157.574 124.617 1.00 30.76  ? 124 LEU B CB    1 
ATOM   3547 C CG    . LEU B 1 124 ? 145.387 156.124 124.506 1.00 30.76  ? 124 LEU B CG    1 
ATOM   3548 C CD1   . LEU B 1 124 ? 144.305 155.822 125.530 1.00 30.76  ? 124 LEU B CD1   1 
ATOM   3549 C CD2   . LEU B 1 124 ? 144.910 155.808 123.101 1.00 30.76  ? 124 LEU B CD2   1 
ATOM   3550 N N     . ILE B 1 125 ? 148.112 159.818 124.722 1.00 28.93  ? 125 ILE B N     1 
ATOM   3551 C CA    . ILE B 1 125 ? 148.448 161.220 124.948 1.00 28.93  ? 125 ILE B CA    1 
ATOM   3552 C C     . ILE B 1 125 ? 149.234 161.774 123.767 1.00 28.93  ? 125 ILE B C     1 
ATOM   3553 O O     . ILE B 1 125 ? 149.082 162.943 123.397 1.00 28.93  ? 125 ILE B O     1 
ATOM   3554 C CB    . ILE B 1 125 ? 149.212 161.384 126.273 1.00 28.93  ? 125 ILE B CB    1 
ATOM   3555 C CG1   . ILE B 1 125 ? 148.362 160.859 127.426 1.00 28.93  ? 125 ILE B CG1   1 
ATOM   3556 C CG2   . ILE B 1 125 ? 149.570 162.841 126.505 1.00 28.93  ? 125 ILE B CG2   1 
ATOM   3557 C CD1   . ILE B 1 125 ? 147.069 161.570 127.595 1.00 28.93  ? 125 ILE B CD1   1 
ATOM   3558 N N     . GLU B 1 126 ? 150.084 160.947 123.153 1.00 36.09  ? 126 GLU B N     1 
ATOM   3559 C CA    . GLU B 1 126 ? 150.794 161.385 121.956 1.00 36.09  ? 126 GLU B CA    1 
ATOM   3560 C C     . GLU B 1 126 ? 149.834 161.588 120.790 1.00 36.09  ? 126 GLU B C     1 
ATOM   3561 O O     . GLU B 1 126 ? 149.986 162.540 120.014 1.00 36.09  ? 126 GLU B O     1 
ATOM   3562 C CB    . GLU B 1 126 ? 151.886 160.380 121.591 1.00 36.09  ? 126 GLU B CB    1 
ATOM   3563 C CG    . GLU B 1 126 ? 153.063 160.358 122.559 1.00 36.09  ? 126 GLU B CG    1 
ATOM   3564 C CD    . GLU B 1 126 ? 153.833 161.664 122.592 1.00 36.09  ? 126 GLU B CD    1 
ATOM   3565 O OE1   . GLU B 1 126 ? 153.814 162.396 121.580 1.00 36.09  ? 126 GLU B OE1   1 
ATOM   3566 O OE2   . GLU B 1 126 ? 154.462 161.957 123.631 1.00 36.09  ? 126 GLU B OE2   1 
ATOM   3567 N N     . ILE B 1 127 ? 148.834 160.711 120.654 1.00 28.04  ? 127 ILE B N     1 
ATOM   3568 C CA    . ILE B 1 127 ? 147.801 160.925 119.640 1.00 28.04  ? 127 ILE B CA    1 
ATOM   3569 C C     . ILE B 1 127 ? 147.135 162.278 119.850 1.00 28.04  ? 127 ILE B C     1 
ATOM   3570 O O     . ILE B 1 127 ? 146.942 163.056 118.907 1.00 28.04  ? 127 ILE B O     1 
ATOM   3571 C CB    . ILE B 1 127 ? 146.757 159.797 119.672 1.00 28.04  ? 127 ILE B CB    1 
ATOM   3572 C CG1   . ILE B 1 127 ? 147.346 158.475 119.200 1.00 28.04  ? 127 ILE B CG1   1 
ATOM   3573 C CG2   . ILE B 1 127 ? 145.582 160.159 118.792 1.00 28.04  ? 127 ILE B CG2   1 
ATOM   3574 C CD1   . ILE B 1 127 ? 146.342 157.355 119.257 1.00 28.04  ? 127 ILE B CD1   1 
ATOM   3575 N N     . TRP B 1 128 ? 146.758 162.566 121.095 1.00 23.74  ? 128 TRP B N     1 
ATOM   3576 C CA    . TRP B 1 128 ? 146.084 163.824 121.393 1.00 23.74  ? 128 TRP B CA    1 
ATOM   3577 C C     . TRP B 1 128 ? 146.985 165.021 121.110 1.00 23.74  ? 128 TRP B C     1 
ATOM   3578 O O     . TRP B 1 128 ? 146.537 166.029 120.545 1.00 23.74  ? 128 TRP B O     1 
ATOM   3579 C CB    . TRP B 1 128 ? 145.624 163.836 122.845 1.00 23.74  ? 128 TRP B CB    1 
ATOM   3580 C CG    . TRP B 1 128 ? 144.310 163.167 123.074 1.00 23.74  ? 128 TRP B CG    1 
ATOM   3581 C CD1   . TRP B 1 128 ? 143.367 162.861 122.139 1.00 23.74  ? 128 TRP B CD1   1 
ATOM   3582 C CD2   . TRP B 1 128 ? 143.774 162.759 124.334 1.00 23.74  ? 128 TRP B CD2   1 
ATOM   3583 N NE1   . TRP B 1 128 ? 142.289 162.257 122.737 1.00 23.74  ? 128 TRP B NE1   1 
ATOM   3584 C CE2   . TRP B 1 128 ? 142.514 162.187 124.086 1.00 23.74  ? 128 TRP B CE2   1 
ATOM   3585 C CE3   . TRP B 1 128 ? 144.245 162.811 125.647 1.00 23.74  ? 128 TRP B CE3   1 
ATOM   3586 C CZ2   . TRP B 1 128 ? 141.718 161.673 125.103 1.00 23.74  ? 128 TRP B CZ2   1 
ATOM   3587 C CZ3   . TRP B 1 128 ? 143.457 162.302 126.652 1.00 23.74  ? 128 TRP B CZ3   1 
ATOM   3588 C CH2   . TRP B 1 128 ? 142.207 161.739 126.377 1.00 23.74  ? 128 TRP B CH2   1 
ATOM   3589 N N     . LYS B 1 129 ? 148.255 164.933 121.510 1.00 27.37  ? 129 LYS B N     1 
ATOM   3590 C CA    . LYS B 1 129 ? 149.197 166.012 121.238 1.00 27.37  ? 129 LYS B CA    1 
ATOM   3591 C C     . LYS B 1 129 ? 149.330 166.253 119.743 1.00 27.37  ? 129 LYS B C     1 
ATOM   3592 O O     . LYS B 1 129 ? 149.451 167.400 119.297 1.00 27.37  ? 129 LYS B O     1 
ATOM   3593 C CB    . LYS B 1 129 ? 150.558 165.684 121.849 1.00 27.37  ? 129 LYS B CB    1 
ATOM   3594 C CG    . LYS B 1 129 ? 150.654 165.931 123.342 1.00 27.37  ? 129 LYS B CG    1 
ATOM   3595 C CD    . LYS B 1 129 ? 152.036 165.575 123.859 1.00 27.37  ? 129 LYS B CD    1 
ATOM   3596 C CE    . LYS B 1 129 ? 153.118 166.263 123.043 1.00 27.37  ? 129 LYS B CE    1 
ATOM   3597 N NZ    . LYS B 1 129 ? 154.483 165.841 123.454 1.00 27.37  ? 129 LYS B NZ    1 
ATOM   3598 N N     . ALA B 1 130 ? 149.313 165.180 118.952 1.00 28.51  ? 130 ALA B N     1 
ATOM   3599 C CA    . ALA B 1 130 ? 149.370 165.327 117.504 1.00 28.51  ? 130 ALA B CA    1 
ATOM   3600 C C     . ALA B 1 130 ? 148.114 166.002 116.967 1.00 28.51  ? 130 ALA B C     1 
ATOM   3601 O O     . ALA B 1 130 ? 148.194 166.892 116.112 1.00 28.51  ? 130 ALA B O     1 
ATOM   3602 C CB    . ALA B 1 130 ? 149.568 163.963 116.847 1.00 28.51  ? 130 ALA B CB    1 
ATOM   3603 N N     . VAL B 1 131 ? 146.941 165.594 117.457 1.00 21.49  ? 131 VAL B N     1 
ATOM   3604 C CA    . VAL B 1 131 ? 145.700 166.064 116.845 1.00 21.49  ? 131 VAL B CA    1 
ATOM   3605 C C     . VAL B 1 131 ? 145.410 167.508 117.242 1.00 21.49  ? 131 VAL B C     1 
ATOM   3606 O O     . VAL B 1 131 ? 144.728 168.235 116.511 1.00 21.49  ? 131 VAL B O     1 
ATOM   3607 C CB    . VAL B 1 131 ? 144.522 165.133 117.187 1.00 21.49  ? 131 VAL B CB    1 
ATOM   3608 C CG1   . VAL B 1 131 ? 144.221 165.161 118.665 1.00 21.49  ? 131 VAL B CG1   1 
ATOM   3609 C CG2   . VAL B 1 131 ? 143.289 165.507 116.371 1.00 21.49  ? 131 VAL B CG2   1 
ATOM   3610 N N     . GLY B 1 132 ? 145.934 167.965 118.380 1.00 25.51  ? 132 GLY B N     1 
ATOM   3611 C CA    . GLY B 1 132 ? 145.733 169.375 118.664 1.00 25.51  ? 132 GLY B CA    1 
ATOM   3612 C C     . GLY B 1 132 ? 145.513 169.856 120.085 1.00 25.51  ? 132 GLY B C     1 
ATOM   3613 O O     . GLY B 1 132 ? 145.270 171.051 120.283 1.00 25.51  ? 132 GLY B O     1 
ATOM   3614 N N     . MET B 1 133 ? 145.555 168.965 121.072 1.00 25.23  ? 133 MET B N     1 
ATOM   3615 C CA    . MET B 1 133 ? 145.522 169.401 122.464 1.00 25.23  ? 133 MET B CA    1 
ATOM   3616 C C     . MET B 1 133 ? 146.584 170.464 122.714 1.00 25.23  ? 133 MET B C     1 
ATOM   3617 O O     . MET B 1 133 ? 147.756 170.279 122.374 1.00 25.23  ? 133 MET B O     1 
ATOM   3618 C CB    . MET B 1 133 ? 145.753 168.209 123.390 1.00 25.23  ? 133 MET B CB    1 
ATOM   3619 C CG    . MET B 1 133 ? 144.743 167.101 123.237 1.00 25.23  ? 133 MET B CG    1 
ATOM   3620 S SD    . MET B 1 133 ? 144.371 166.278 124.798 1.00 25.23  ? 133 MET B SD    1 
ATOM   3621 C CE    . MET B 1 133 ? 143.535 167.568 125.682 1.00 25.23  ? 133 MET B CE    1 
ATOM   3622 N N     . ASP B 1 134 ? 146.173 171.580 123.318 1.00 31.26  ? 134 ASP B N     1 
ATOM   3623 C CA    . ASP B 1 134 ? 147.087 172.688 123.606 1.00 31.26  ? 134 ASP B CA    1 
ATOM   3624 C C     . ASP B 1 134 ? 147.870 172.386 124.885 1.00 31.26  ? 134 ASP B C     1 
ATOM   3625 O O     . ASP B 1 134 ? 147.810 173.101 125.887 1.00 31.26  ? 134 ASP B O     1 
ATOM   3626 C CB    . ASP B 1 134 ? 146.324 174.001 123.711 1.00 31.26  ? 134 ASP B CB    1 
ATOM   3627 C CG    . ASP B 1 134 ? 145.734 174.437 122.387 1.00 31.26  ? 134 ASP B CG    1 
ATOM   3628 O OD1   . ASP B 1 134 ? 145.444 173.560 121.548 1.00 31.26  ? 134 ASP B OD1   1 
ATOM   3629 O OD2   . ASP B 1 134 ? 145.557 175.657 122.185 1.00 31.26  ? 134 ASP B OD2   1 
ATOM   3630 N N     . VAL B 1 135 ? 148.627 171.290 124.826 1.00 34.61  ? 135 VAL B N     1 
ATOM   3631 C CA    . VAL B 1 135 ? 149.461 170.899 125.956 1.00 34.61  ? 135 VAL B CA    1 
ATOM   3632 C C     . VAL B 1 135 ? 150.582 171.908 126.163 1.00 34.61  ? 135 VAL B C     1 
ATOM   3633 O O     . VAL B 1 135 ? 150.953 172.222 127.301 1.00 34.61  ? 135 VAL B O     1 
ATOM   3634 C CB    . VAL B 1 135 ? 150.006 169.477 125.742 1.00 34.61  ? 135 VAL B CB    1 
ATOM   3635 C CG1   . VAL B 1 135 ? 150.758 169.002 126.973 1.00 34.61  ? 135 VAL B CG1   1 
ATOM   3636 C CG2   . VAL B 1 135 ? 148.874 168.526 125.397 1.00 34.61  ? 135 VAL B CG2   1 
ATOM   3637 N N     . GLU B 1 136 ? 151.134 172.440 125.070 1.00 45.32  ? 136 GLU B N     1 
ATOM   3638 C CA    . GLU B 1 136 ? 152.225 173.402 125.168 1.00 45.32  ? 136 GLU B CA    1 
ATOM   3639 C C     . GLU B 1 136 ? 151.796 174.707 125.827 1.00 45.32  ? 136 GLU B C     1 
ATOM   3640 O O     . GLU B 1 136 ? 152.656 175.461 126.294 1.00 45.32  ? 136 GLU B O     1 
ATOM   3641 C CB    . GLU B 1 136 ? 152.799 173.690 123.780 1.00 45.32  ? 136 GLU B CB    1 
ATOM   3642 C CG    . GLU B 1 136 ? 153.327 172.461 123.056 1.00 45.32  ? 136 GLU B CG    1 
ATOM   3643 C CD    . GLU B 1 136 ? 154.778 172.166 123.381 1.00 45.32  ? 136 GLU B CD    1 
ATOM   3644 O OE1   . GLU B 1 136 ? 155.312 172.769 124.336 1.00 45.32  ? 136 GLU B OE1   1 
ATOM   3645 O OE2   . GLU B 1 136 ? 155.385 171.330 122.680 1.00 45.32  ? 136 GLU B OE2   1 
ATOM   3646 N N     . GLY B 1 137 ? 150.493 174.990 125.875 1.00 40.11  ? 137 GLY B N     1 
ATOM   3647 C CA    . GLY B 1 137 ? 150.036 176.225 126.489 1.00 40.11  ? 137 GLY B CA    1 
ATOM   3648 C C     . GLY B 1 137 ? 150.203 176.242 127.995 1.00 40.11  ? 137 GLY B C     1 
ATOM   3649 O O     . GLY B 1 137 ? 150.190 177.309 128.613 1.00 40.11  ? 137 GLY B O     1 
ATOM   3650 N N     . GLY B 1 138 ? 150.361 175.070 128.606 1.00 42.91  ? 138 GLY B N     1 
ATOM   3651 C CA    . GLY B 1 138 ? 150.528 174.969 130.038 1.00 42.91  ? 138 GLY B CA    1 
ATOM   3652 C C     . GLY B 1 138 ? 149.245 174.968 130.838 1.00 42.91  ? 138 GLY B C     1 
ATOM   3653 O O     . GLY B 1 138 ? 149.303 174.837 132.068 1.00 42.91  ? 138 GLY B O     1 
ATOM   3654 N N     . LYS B 1 139 ? 148.092 175.107 130.190 1.00 40.38  ? 139 LYS B N     1 
ATOM   3655 C CA    . LYS B 1 139 ? 146.809 175.086 130.876 1.00 40.38  ? 139 LYS B CA    1 
ATOM   3656 C C     . LYS B 1 139 ? 146.210 173.690 130.973 1.00 40.38  ? 139 LYS B C     1 
ATOM   3657 O O     . LYS B 1 139 ? 145.119 173.538 131.529 1.00 40.38  ? 139 LYS B O     1 
ATOM   3658 C CB    . LYS B 1 139 ? 145.817 176.021 130.178 1.00 40.38  ? 139 LYS B CB    1 
ATOM   3659 C CG    . LYS B 1 139 ? 146.234 177.480 130.186 1.00 40.38  ? 139 LYS B CG    1 
ATOM   3660 C CD    . LYS B 1 139 ? 146.260 178.032 131.601 1.00 40.38  ? 139 LYS B CD    1 
ATOM   3661 C CE    . LYS B 1 139 ? 146.629 179.505 131.611 1.00 40.38  ? 139 LYS B CE    1 
ATOM   3662 N NZ    . LYS B 1 139 ? 146.700 180.048 132.995 1.00 40.38  ? 139 LYS B NZ    1 
ATOM   3663 N N     . VAL B 1 140 ? 146.888 172.675 130.447 1.00 36.08  ? 140 VAL B N     1 
ATOM   3664 C CA    . VAL B 1 140 ? 146.419 171.297 130.505 1.00 36.08  ? 140 VAL B CA    1 
ATOM   3665 C C     . VAL B 1 140 ? 147.452 170.472 131.257 1.00 36.08  ? 140 VAL B C     1 
ATOM   3666 O O     . VAL B 1 140 ? 148.638 170.483 130.905 1.00 36.08  ? 140 VAL B O     1 
ATOM   3667 C CB    . VAL B 1 140 ? 146.177 170.719 129.101 1.00 36.08  ? 140 VAL B CB    1 
ATOM   3668 C CG1   . VAL B 1 140 ? 145.583 169.326 129.198 1.00 36.08  ? 140 VAL B CG1   1 
ATOM   3669 C CG2   . VAL B 1 140 ? 145.273 171.638 128.307 1.00 36.08  ? 140 VAL B CG2   1 
ATOM   3670 N N     . GLU B 1 141 ? 147.002 169.761 132.287 1.00 41.97  ? 141 GLU B N     1 
ATOM   3671 C CA    . GLU B 1 141 ? 147.853 168.888 133.082 1.00 41.97  ? 141 GLU B CA    1 
ATOM   3672 C C     . GLU B 1 141 ? 147.330 167.466 132.964 1.00 41.97  ? 141 GLU B C     1 
ATOM   3673 O O     . GLU B 1 141 ? 146.120 167.238 133.055 1.00 41.97  ? 141 GLU B O     1 
ATOM   3674 C CB    . GLU B 1 141 ? 147.879 169.324 134.547 1.00 41.97  ? 141 GLU B CB    1 
ATOM   3675 C CG    . GLU B 1 141 ? 147.940 170.827 134.736 1.00 41.97  ? 141 GLU B CG    1 
ATOM   3676 C CD    . GLU B 1 141 ? 148.070 171.227 136.191 1.00 41.97  ? 141 GLU B CD    1 
ATOM   3677 O OE1   . GLU B 1 141 ? 148.157 170.325 137.051 1.00 41.97  ? 141 GLU B OE1   1 
ATOM   3678 O OE2   . GLU B 1 141 ? 148.083 172.443 136.475 1.00 41.97  ? 141 GLU B OE2   1 
ATOM   3679 N N     . PHE B 1 142 ? 148.237 166.517 132.757 1.00 38.43  ? 142 PHE B N     1 
ATOM   3680 C CA    . PHE B 1 142 ? 147.879 165.115 132.585 1.00 38.43  ? 142 PHE B CA    1 
ATOM   3681 C C     . PHE B 1 142 ? 148.306 164.369 133.843 1.00 38.43  ? 142 PHE B C     1 
ATOM   3682 O O     . PHE B 1 142 ? 149.479 164.011 133.991 1.00 38.43  ? 142 PHE B O     1 
ATOM   3683 C CB    . PHE B 1 142 ? 148.551 164.528 131.348 1.00 38.43  ? 142 PHE B CB    1 
ATOM   3684 C CG    . PHE B 1 142 ? 148.083 165.135 130.059 1.00 38.43  ? 142 PHE B CG    1 
ATOM   3685 C CD1   . PHE B 1 142 ? 147.232 164.445 129.221 1.00 38.43  ? 142 PHE B CD1   1 
ATOM   3686 C CD2   . PHE B 1 142 ? 148.525 166.387 129.669 1.00 38.43  ? 142 PHE B CD2   1 
ATOM   3687 C CE1   . PHE B 1 142 ? 146.810 164.999 128.029 1.00 38.43  ? 142 PHE B CE1   1 
ATOM   3688 C CE2   . PHE B 1 142 ? 148.109 166.945 128.481 1.00 38.43  ? 142 PHE B CE2   1 
ATOM   3689 C CZ    . PHE B 1 142 ? 147.250 166.250 127.660 1.00 38.43  ? 142 PHE B CZ    1 
ATOM   3690 N N     . LEU B 1 143 ? 147.357 164.133 134.743 1.00 37.27  ? 143 LEU B N     1 
ATOM   3691 C CA    . LEU B 1 143 ? 147.647 163.551 136.045 1.00 37.27  ? 143 LEU B CA    1 
ATOM   3692 C C     . LEU B 1 143 ? 147.354 162.057 136.025 1.00 37.27  ? 143 LEU B C     1 
ATOM   3693 O O     . LEU B 1 143 ? 146.222 161.643 135.755 1.00 37.27  ? 143 LEU B O     1 
ATOM   3694 C CB    . LEU B 1 143 ? 146.825 164.238 137.137 1.00 37.27  ? 143 LEU B CB    1 
ATOM   3695 C CG    . LEU B 1 143 ? 147.087 165.736 137.302 1.00 37.27  ? 143 LEU B CG    1 
ATOM   3696 C CD1   . LEU B 1 143 ? 146.281 166.311 138.455 1.00 37.27  ? 143 LEU B CD1   1 
ATOM   3697 C CD2   . LEU B 1 143 ? 148.568 166.002 137.495 1.00 37.27  ? 143 LEU B CD2   1 
ATOM   3698 N N     . TRP B 1 144 ? 148.374 161.255 136.320 1.00 36.23  ? 144 TRP B N     1 
ATOM   3699 C CA    . TRP B 1 144 ? 148.224 159.813 136.430 1.00 36.23  ? 144 TRP B CA    1 
ATOM   3700 C C     . TRP B 1 144 ? 147.643 159.450 137.787 1.00 36.23  ? 144 TRP B C     1 
ATOM   3701 O O     . TRP B 1 144 ? 148.044 160.000 138.817 1.00 36.23  ? 144 TRP B O     1 
ATOM   3702 C CB    . TRP B 1 144 ? 149.565 159.110 136.228 1.00 36.23  ? 144 TRP B CB    1 
ATOM   3703 C CG    . TRP B 1 144 ? 150.084 159.223 134.838 1.00 36.23  ? 144 TRP B CG    1 
ATOM   3704 C CD1   . TRP B 1 144 ? 150.855 160.221 134.324 1.00 36.23  ? 144 TRP B CD1   1 
ATOM   3705 C CD2   . TRP B 1 144 ? 149.857 158.299 133.771 1.00 36.23  ? 144 TRP B CD2   1 
ATOM   3706 N NE1   . TRP B 1 144 ? 151.125 159.974 133.000 1.00 36.23  ? 144 TRP B NE1   1 
ATOM   3707 C CE2   . TRP B 1 144 ? 150.523 158.798 132.637 1.00 36.23  ? 144 TRP B CE2   1 
ATOM   3708 C CE3   . TRP B 1 144 ? 149.155 157.095 133.665 1.00 36.23  ? 144 TRP B CE3   1 
ATOM   3709 C CZ2   . TRP B 1 144 ? 150.507 158.138 131.414 1.00 36.23  ? 144 TRP B CZ2   1 
ATOM   3710 C CZ3   . TRP B 1 144 ? 149.142 156.441 132.452 1.00 36.23  ? 144 TRP B CZ3   1 
ATOM   3711 C CH2   . TRP B 1 144 ? 149.812 156.963 131.342 1.00 36.23  ? 144 TRP B CH2   1 
ATOM   3712 N N     . SER B 1 145 ? 146.685 158.524 137.779 1.00 35.09  ? 145 SER B N     1 
ATOM   3713 C CA    . SER B 1 145 ? 146.016 158.145 139.018 1.00 35.09  ? 145 SER B CA    1 
ATOM   3714 C C     . SER B 1 145 ? 146.992 157.523 140.009 1.00 35.09  ? 145 SER B C     1 
ATOM   3715 O O     . SER B 1 145 ? 147.009 157.890 141.190 1.00 35.09  ? 145 SER B O     1 
ATOM   3716 C CB    . SER B 1 145 ? 144.866 157.186 138.719 1.00 35.09  ? 145 SER B CB    1 
ATOM   3717 O OG    . SER B 1 145 ? 145.339 156.038 138.041 1.00 35.09  ? 145 SER B OG    1 
ATOM   3718 N N     . SER B 1 146 ? 147.828 156.589 139.544 1.00 33.89  ? 146 SER B N     1 
ATOM   3719 C CA    . SER B 1 146 ? 148.721 155.888 140.460 1.00 33.89  ? 146 SER B CA    1 
ATOM   3720 C C     . SER B 1 146 ? 149.714 156.847 141.097 1.00 33.89  ? 146 SER B C     1 
ATOM   3721 O O     . SER B 1 146 ? 149.885 156.857 142.321 1.00 33.89  ? 146 SER B O     1 
ATOM   3722 C CB    . SER B 1 146 ? 149.466 154.768 139.737 1.00 33.89  ? 146 SER B CB    1 
ATOM   3723 O OG    . SER B 1 146 ? 150.169 155.251 138.609 1.00 33.89  ? 146 SER B OG    1 
ATOM   3724 N N     . LYS B 1 147 ? 150.383 157.661 140.280 1.00 33.58  ? 147 LYS B N     1 
ATOM   3725 C CA    . LYS B 1 147 ? 151.425 158.534 140.805 1.00 33.58  ? 147 LYS B CA    1 
ATOM   3726 C C     . LYS B 1 147 ? 150.845 159.571 141.758 1.00 33.58  ? 147 LYS B C     1 
ATOM   3727 O O     . LYS B 1 147 ? 151.381 159.794 142.850 1.00 33.58  ? 147 LYS B O     1 
ATOM   3728 C CB    . LYS B 1 147 ? 152.174 159.205 139.655 1.00 33.58  ? 147 LYS B CB    1 
ATOM   3729 C CG    . LYS B 1 147 ? 153.287 160.130 140.109 1.00 33.58  ? 147 LYS B CG    1 
ATOM   3730 C CD    . LYS B 1 147 ? 153.995 160.777 138.931 1.00 33.58  ? 147 LYS B CD    1 
ATOM   3731 C CE    . LYS B 1 147 ? 154.593 159.732 138.006 1.00 33.58  ? 147 LYS B CE    1 
ATOM   3732 N NZ    . LYS B 1 147 ? 155.619 158.919 138.711 1.00 33.58  ? 147 LYS B NZ    1 
ATOM   3733 N N     . GLU B 1 148 ? 149.730 160.195 141.373 1.00 35.19  ? 148 GLU B N     1 
ATOM   3734 C CA    . GLU B 1 148 ? 149.132 161.225 142.214 1.00 35.19  ? 148 GLU B CA    1 
ATOM   3735 C C     . GLU B 1 148 ? 148.609 160.632 143.519 1.00 35.19  ? 148 GLU B C     1 
ATOM   3736 O O     . GLU B 1 148 ? 148.771 161.225 144.593 1.00 35.19  ? 148 GLU B O     1 
ATOM   3737 C CB    . GLU B 1 148 ? 148.016 161.934 141.449 1.00 35.19  ? 148 GLU B CB    1 
ATOM   3738 C CG    . GLU B 1 148 ? 147.648 163.297 141.999 1.00 35.19  ? 148 GLU B CG    1 
ATOM   3739 C CD    . GLU B 1 148 ? 148.867 164.155 142.279 1.00 35.19  ? 148 GLU B CD    1 
ATOM   3740 O OE1   . GLU B 1 148 ? 149.756 164.229 141.398 1.00 35.19  ? 148 GLU B OE1   1 
ATOM   3741 O OE2   . GLU B 1 148 ? 148.938 164.752 143.369 1.00 35.19  ? 148 GLU B OE2   1 
ATOM   3742 N N     . ILE B 1 149 ? 147.972 159.459 143.445 1.00 32.97  ? 149 ILE B N     1 
ATOM   3743 C CA    . ILE B 1 149 ? 147.450 158.817 144.649 1.00 32.97  ? 149 ILE B CA    1 
ATOM   3744 C C     . ILE B 1 149 ? 148.591 158.435 145.583 1.00 32.97  ? 149 ILE B C     1 
ATOM   3745 O O     . ILE B 1 149 ? 148.538 158.676 146.795 1.00 32.97  ? 149 ILE B O     1 
ATOM   3746 C CB    . ILE B 1 149 ? 146.601 157.588 144.281 1.00 32.97  ? 149 ILE B CB    1 
ATOM   3747 C CG1   . ILE B 1 149 ? 145.197 158.016 143.854 1.00 32.97  ? 149 ILE B CG1   1 
ATOM   3748 C CG2   . ILE B 1 149 ? 146.523 156.643 145.475 1.00 32.97  ? 149 ILE B CG2   1 
ATOM   3749 C CD1   . ILE B 1 149 ? 144.326 156.884 143.342 1.00 32.97  ? 149 ILE B CD1   1 
ATOM   3750 N N     . ASN B 1 150 ? 149.647 157.837 145.035 1.00 28.45  ? 150 ASN B N     1 
ATOM   3751 C CA    . ASN B 1 150 ? 150.742 157.394 145.885 1.00 28.45  ? 150 ASN B CA    1 
ATOM   3752 C C     . ASN B 1 150 ? 151.572 158.576 146.369 1.00 28.45  ? 150 ASN B C     1 
ATOM   3753 O O     . ASN B 1 150 ? 152.362 158.444 147.311 1.00 28.45  ? 150 ASN B O     1 
ATOM   3754 C CB    . ASN B 1 150 ? 151.599 156.378 145.134 1.00 28.45  ? 150 ASN B CB    1 
ATOM   3755 C CG    . ASN B 1 150 ? 150.811 155.141 144.732 1.00 28.45  ? 150 ASN B CG    1 
ATOM   3756 O OD1   . ASN B 1 150 ? 149.719 154.894 145.244 1.00 28.45  ? 150 ASN B OD1   1 
ATOM   3757 N ND2   . ASN B 1 150 ? 151.371 154.348 143.825 1.00 28.45  ? 150 ASN B ND2   1 
ATOM   3758 N N     . ALA B 1 151 ? 151.412 159.741 145.738 1.00 33.61  ? 151 ALA B N     1 
ATOM   3759 C CA    . ALA B 1 151 ? 152.041 160.942 146.274 1.00 33.61  ? 151 ALA B CA    1 
ATOM   3760 C C     . ALA B 1 151 ? 151.239 161.504 147.441 1.00 33.61  ? 151 ALA B C     1 
ATOM   3761 O O     . ALA B 1 151 ? 151.784 161.716 148.530 1.00 33.61  ? 151 ALA B O     1 
ATOM   3762 C CB    . ALA B 1 151 ? 152.206 161.992 145.176 1.00 33.61  ? 151 ALA B CB    1 
ATOM   3763 N N     . ARG B 1 152 ? 149.938 161.750 147.238 1.00 38.91  ? 152 ARG B N     1 
ATOM   3764 C CA    . ARG B 1 152 ? 149.070 162.269 148.297 1.00 38.91  ? 152 ARG B CA    1 
ATOM   3765 C C     . ARG B 1 152 ? 147.806 161.410 148.389 1.00 38.91  ? 152 ARG B C     1 
ATOM   3766 O O     . ARG B 1 152 ? 146.756 161.752 147.845 1.00 38.91  ? 152 ARG B O     1 
ATOM   3767 C CB    . ARG B 1 152 ? 148.725 163.737 148.049 1.00 38.91  ? 152 ARG B CB    1 
ATOM   3768 C CG    . ARG B 1 152 ? 149.580 164.724 148.821 1.00 38.91  ? 152 ARG B CG    1 
ATOM   3769 C CD    . ARG B 1 152 ? 149.166 166.154 148.511 1.00 38.91  ? 152 ARG B CD    1 
ATOM   3770 N NE    . ARG B 1 152 ? 149.735 166.629 147.255 1.00 38.91  ? 152 ARG B NE    1 
ATOM   3771 C CZ    . ARG B 1 152 ? 149.082 166.663 146.101 1.00 38.91  ? 152 ARG B CZ    1 
ATOM   3772 N NH1   . ARG B 1 152 ? 147.829 166.252 146.003 1.00 38.91  ? 152 ARG B NH1   1 
ATOM   3773 N NH2   . ARG B 1 152 ? 149.704 167.120 145.018 1.00 38.91  ? 152 ARG B NH2   1 
ATOM   3774 N N     . ALA B 1 153 ? 147.922 160.279 149.078 1.00 40.94  ? 153 ALA B N     1 
ATOM   3775 C CA    . ALA B 1 153 ? 146.780 159.471 149.476 1.00 40.94  ? 153 ALA B CA    1 
ATOM   3776 C C     . ALA B 1 153 ? 146.214 159.847 150.837 1.00 40.94  ? 153 ALA B C     1 
ATOM   3777 O O     . ALA B 1 153 ? 145.051 159.530 151.111 1.00 40.94  ? 153 ALA B O     1 
ATOM   3778 C CB    . ALA B 1 153 ? 147.165 157.988 149.484 1.00 40.94  ? 153 ALA B CB    1 
ATOM   3779 N N     . ASP B 1 154 ? 146.998 160.508 151.691 1.00 39.68  ? 154 ASP B N     1 
ATOM   3780 C CA    . ASP B 1 154 ? 146.488 160.905 152.999 1.00 39.68  ? 154 ASP B CA    1 
ATOM   3781 C C     . ASP B 1 154 ? 145.414 161.978 152.870 1.00 39.68  ? 154 ASP B C     1 
ATOM   3782 O O     . ASP B 1 154 ? 144.641 162.209 153.806 1.00 39.68  ? 154 ASP B O     1 
ATOM   3783 C CB    . ASP B 1 154 ? 147.635 161.387 153.888 1.00 39.68  ? 154 ASP B CB    1 
ATOM   3784 C CG    . ASP B 1 154 ? 148.416 162.531 153.271 1.00 39.68  ? 154 ASP B CG    1 
ATOM   3785 O OD1   . ASP B 1 154 ? 148.118 162.914 152.121 1.00 39.68  ? 154 ASP B OD1   1 
ATOM   3786 O OD2   . ASP B 1 154 ? 149.332 163.050 153.942 1.00 39.68  ? 154 ASP B OD2   1 
ATOM   3787 N N     . GLU B 1 155 ? 145.358 162.652 151.722 1.00 47.06  ? 155 GLU B N     1 
ATOM   3788 C CA    . GLU B 1 155 ? 144.311 163.618 151.423 1.00 47.06  ? 155 GLU B CA    1 
ATOM   3789 C C     . GLU B 1 155 ? 143.248 163.056 150.491 1.00 47.06  ? 155 GLU B C     1 
ATOM   3790 O O     . GLU B 1 155 ? 142.319 163.780 150.121 1.00 47.06  ? 155 GLU B O     1 
ATOM   3791 C CB    . GLU B 1 155 ? 144.921 164.881 150.807 1.00 47.06  ? 155 GLU B CB    1 
ATOM   3792 C CG    . GLU B 1 155 ? 145.798 165.674 151.761 1.00 47.06  ? 155 GLU B CG    1 
ATOM   3793 C CD    . GLU B 1 155 ? 146.414 166.896 151.109 1.00 47.06  ? 155 GLU B CD    1 
ATOM   3794 O OE1   . GLU B 1 155 ? 146.264 167.053 149.879 1.00 47.06  ? 155 GLU B OE1   1 
ATOM   3795 O OE2   . GLU B 1 155 ? 147.049 167.698 151.824 1.00 47.06  ? 155 GLU B OE2   1 
ATOM   3796 N N     . TYR B 1 156 ? 143.360 161.788 150.105 1.00 63.87  ? 156 TYR B N     1 
ATOM   3797 C CA    . TYR B 1 156 ? 142.480 161.175 149.119 1.00 63.87  ? 156 TYR B CA    1 
ATOM   3798 C C     . TYR B 1 156 ? 141.657 160.027 149.680 1.00 63.87  ? 156 TYR B C     1 
ATOM   3799 O O     . TYR B 1 156 ? 140.436 160.007 149.510 1.00 63.87  ? 156 TYR B O     1 
ATOM   3800 C CB    . TYR B 1 156 ? 143.303 160.668 147.934 1.00 63.87  ? 156 TYR B CB    1 
ATOM   3801 C CG    . TYR B 1 156 ? 142.508 159.889 146.919 1.00 63.87  ? 156 TYR B CG    1 
ATOM   3802 C CD1   . TYR B 1 156 ? 141.804 160.537 145.920 1.00 63.87  ? 156 TYR B CD1   1 
ATOM   3803 C CD2   . TYR B 1 156 ? 142.465 158.505 146.956 1.00 63.87  ? 156 TYR B CD2   1 
ATOM   3804 C CE1   . TYR B 1 156 ? 141.081 159.829 144.991 1.00 63.87  ? 156 TYR B CE1   1 
ATOM   3805 C CE2   . TYR B 1 156 ? 141.743 157.791 146.033 1.00 63.87  ? 156 TYR B CE2   1 
ATOM   3806 C CZ    . TYR B 1 156 ? 141.054 158.457 145.053 1.00 63.87  ? 156 TYR B CZ    1 
ATOM   3807 O OH    . TYR B 1 156 ? 140.334 157.745 144.127 1.00 63.87  ? 156 TYR B OH    1 
ATOM   3808 N N     . TRP B 1 157 ? 142.298 159.064 150.326 1.00 63.87  ? 157 TRP B N     1 
ATOM   3809 C CA    . TRP B 1 157 ? 141.601 157.901 150.863 1.00 63.87  ? 157 TRP B CA    1 
ATOM   3810 C C     . TRP B 1 157 ? 140.713 158.267 152.051 1.00 63.87  ? 157 TRP B C     1 
ATOM   3811 O O     . TRP B 1 157 ? 139.634 157.679 152.205 1.00 63.87  ? 157 TRP B O     1 
ATOM   3812 C CB    . TRP B 1 157 ? 142.602 156.811 151.242 1.00 63.87  ? 157 TRP B CB    1 
ATOM   3813 C CG    . TRP B 1 157 ? 143.119 156.068 150.054 1.00 63.87  ? 157 TRP B CG    1 
ATOM   3814 C CD1   . TRP B 1 157 ? 144.388 156.094 149.559 1.00 63.87  ? 157 TRP B CD1   1 
ATOM   3815 C CD2   . TRP B 1 157 ? 142.374 155.193 149.201 1.00 63.87  ? 157 TRP B CD2   1 
ATOM   3816 N NE1   . TRP B 1 157 ? 144.482 155.285 148.455 1.00 63.87  ? 157 TRP B NE1   1 
ATOM   3817 C CE2   . TRP B 1 157 ? 143.257 154.720 148.214 1.00 63.87  ? 157 TRP B CE2   1 
ATOM   3818 C CE3   . TRP B 1 157 ? 141.046 154.761 149.180 1.00 63.87  ? 157 TRP B CE3   1 
ATOM   3819 C CZ2   . TRP B 1 157 ? 142.856 153.839 147.218 1.00 63.87  ? 157 TRP B CZ2   1 
ATOM   3820 C CZ3   . TRP B 1 157 ? 140.651 153.886 148.190 1.00 63.87  ? 157 TRP B CZ3   1 
ATOM   3821 C CH2   . TRP B 1 157 ? 141.553 153.434 147.223 1.00 63.87  ? 157 TRP B CH2   1 
ATOM   3822 N N     . PRO B 1 158 ? 141.112 159.205 152.919 1.00 43.94  ? 158 PRO B N     1 
ATOM   3823 C CA    . PRO B 1 158 ? 140.127 159.742 153.869 1.00 43.94  ? 158 PRO B CA    1 
ATOM   3824 C C     . PRO B 1 158 ? 138.909 160.330 153.183 1.00 43.94  ? 158 PRO B C     1 
ATOM   3825 O O     . PRO B 1 158 ? 137.792 160.183 153.686 1.00 43.94  ? 158 PRO B O     1 
ATOM   3826 C CB    . PRO B 1 158 ? 140.930 160.802 154.628 1.00 43.94  ? 158 PRO B CB    1 
ATOM   3827 C CG    . PRO B 1 158 ? 142.293 160.248 154.643 1.00 43.94  ? 158 PRO B CG    1 
ATOM   3828 C CD    . PRO B 1 158 ? 142.476 159.642 153.276 1.00 43.94  ? 158 PRO B CD    1 
ATOM   3829 N N     . LEU B 1 159 ? 139.091 160.983 152.034 1.00 37.83  ? 159 LEU B N     1 
ATOM   3830 C CA    . LEU B 1 159 ? 137.951 161.514 151.291 1.00 37.83  ? 159 LEU B CA    1 
ATOM   3831 C C     . LEU B 1 159 ? 137.057 160.403 150.755 1.00 37.83  ? 159 LEU B C     1 
ATOM   3832 O O     . LEU B 1 159 ? 135.826 160.525 150.785 1.00 37.83  ? 159 LEU B O     1 
ATOM   3833 C CB    . LEU B 1 159 ? 138.444 162.394 150.146 1.00 37.83  ? 159 LEU B CB    1 
ATOM   3834 C CG    . LEU B 1 159 ? 137.402 163.269 149.459 1.00 37.83  ? 159 LEU B CG    1 
ATOM   3835 C CD1   . LEU B 1 159 ? 136.936 164.375 150.389 1.00 37.83  ? 159 LEU B CD1   1 
ATOM   3836 C CD2   . LEU B 1 159 ? 137.991 163.842 148.193 1.00 37.83  ? 159 LEU B CD2   1 
ATOM   3837 N N     . VAL B 1 160 ? 137.653 159.323 150.246 1.00 36.15  ? 160 VAL B N     1 
ATOM   3838 C CA    . VAL B 1 160 ? 136.858 158.197 149.773 1.00 36.15  ? 160 VAL B CA    1 
ATOM   3839 C C     . VAL B 1 160 ? 136.105 157.531 150.916 1.00 36.15  ? 160 VAL B C     1 
ATOM   3840 O O     . VAL B 1 160 ? 134.934 157.162 150.756 1.00 36.15  ? 160 VAL B O     1 
ATOM   3841 C CB    . VAL B 1 160 ? 137.744 157.172 149.049 1.00 36.15  ? 160 VAL B CB    1 
ATOM   3842 C CG1   . VAL B 1 160 ? 136.896 156.077 148.448 1.00 36.15  ? 160 VAL B CG1   1 
ATOM   3843 C CG2   . VAL B 1 160 ? 138.575 157.850 147.980 1.00 36.15  ? 160 VAL B CG2   1 
ATOM   3844 N N     . LEU B 1 161 ? 136.735 157.378 152.078 1.00 33.41  ? 161 LEU B N     1 
ATOM   3845 C CA    . LEU B 1 161 ? 136.007 156.878 153.234 1.00 33.41  ? 161 LEU B CA    1 
ATOM   3846 C C     . LEU B 1 161 ? 134.908 157.837 153.677 1.00 33.41  ? 161 LEU B C     1 
ATOM   3847 O O     . LEU B 1 161 ? 133.840 157.389 154.100 1.00 33.41  ? 161 LEU B O     1 
ATOM   3848 C CB    . LEU B 1 161 ? 136.976 156.596 154.380 1.00 33.41  ? 161 LEU B CB    1 
ATOM   3849 C CG    . LEU B 1 161 ? 137.620 155.215 154.303 1.00 33.41  ? 161 LEU B CG    1 
ATOM   3850 C CD1   . LEU B 1 161 ? 138.552 154.980 155.468 1.00 33.41  ? 161 LEU B CD1   1 
ATOM   3851 C CD2   . LEU B 1 161 ? 136.528 154.175 154.299 1.00 33.41  ? 161 LEU B CD2   1 
ATOM   3852 N N     . ASP B 1 162 ? 135.141 159.147 153.578 1.00 30.40  ? 162 ASP B N     1 
ATOM   3853 C CA    . ASP B 1 162 ? 134.119 160.114 153.964 1.00 30.40  ? 162 ASP B CA    1 
ATOM   3854 C C     . ASP B 1 162 ? 132.898 160.018 153.059 1.00 30.40  ? 162 ASP B C     1 
ATOM   3855 O O     . ASP B 1 162 ? 131.759 160.038 153.535 1.00 30.40  ? 162 ASP B O     1 
ATOM   3856 C CB    . ASP B 1 162 ? 134.700 161.527 153.940 1.00 30.40  ? 162 ASP B CB    1 
ATOM   3857 C CG    . ASP B 1 162 ? 133.865 162.513 154.731 1.00 30.40  ? 162 ASP B CG    1 
ATOM   3858 O OD1   . ASP B 1 162 ? 132.709 162.770 154.335 1.00 30.40  ? 162 ASP B OD1   1 
ATOM   3859 O OD2   . ASP B 1 162 ? 134.364 163.032 155.751 1.00 30.40  ? 162 ASP B OD2   1 
ATOM   3860 N N     . ILE B 1 163 ? 133.113 159.919 151.744 1.00 30.27  ? 163 ILE B N     1 
ATOM   3861 C CA    . ILE B 1 163 ? 131.978 159.763 150.833 1.00 30.27  ? 163 ILE B CA    1 
ATOM   3862 C C     . ILE B 1 163 ? 131.277 158.430 151.067 1.00 30.27  ? 163 ILE B C     1 
ATOM   3863 O O     . ILE B 1 163 ? 130.039 158.357 151.068 1.00 30.27  ? 163 ILE B O     1 
ATOM   3864 C CB    . ILE B 1 163 ? 132.409 159.951 149.362 1.00 30.27  ? 163 ILE B CB    1 
ATOM   3865 C CG1   . ILE B 1 163 ? 131.205 159.830 148.432 1.00 30.27  ? 163 ILE B CG1   1 
ATOM   3866 C CG2   . ILE B 1 163 ? 133.457 158.968 148.941 1.00 30.27  ? 163 ILE B CG2   1 
ATOM   3867 C CD1   . ILE B 1 163 ? 130.184 160.876 148.624 1.00 30.27  ? 163 ILE B CD1   1 
ATOM   3868 N N     . ALA B 1 164 ? 132.046 157.361 151.298 1.00 33.40  ? 164 ALA B N     1 
ATOM   3869 C CA    . ALA B 1 164 ? 131.434 156.063 151.557 1.00 33.40  ? 164 ALA B CA    1 
ATOM   3870 C C     . ALA B 1 164 ? 130.592 156.089 152.828 1.00 33.40  ? 164 ALA B C     1 
ATOM   3871 O O     . ALA B 1 164 ? 129.553 155.425 152.907 1.00 33.40  ? 164 ALA B O     1 
ATOM   3872 C CB    . ALA B 1 164 ? 132.512 154.985 151.646 1.00 33.40  ? 164 ALA B CB    1 
ATOM   3873 N N     . GLN B 1 165 ? 131.032 156.842 153.837 1.00 36.40  ? 165 GLN B N     1 
ATOM   3874 C CA    . GLN B 1 165 ? 130.275 156.934 155.081 1.00 36.40  ? 165 GLN B CA    1 
ATOM   3875 C C     . GLN B 1 165 ? 129.047 157.819 154.925 1.00 36.40  ? 165 GLN B C     1 
ATOM   3876 O O     . GLN B 1 165 ? 127.970 157.491 155.436 1.00 36.40  ? 165 GLN B O     1 
ATOM   3877 C CB    . GLN B 1 165 ? 131.179 157.451 156.200 1.00 36.40  ? 165 GLN B CB    1 
ATOM   3878 C CG    . GLN B 1 165 ? 130.444 157.885 157.452 1.00 36.40  ? 165 GLN B CG    1 
ATOM   3879 C CD    . GLN B 1 165 ? 131.307 158.735 158.361 1.00 36.40  ? 165 GLN B CD    1 
ATOM   3880 O OE1   . GLN B 1 165 ? 132.451 159.048 158.034 1.00 36.40  ? 165 GLN B OE1   1 
ATOM   3881 N NE2   . GLN B 1 165 ? 130.761 159.118 159.508 1.00 36.40  ? 165 GLN B NE2   1 
ATOM   3882 N N     . LYS B 1 166 ? 129.183 158.942 154.219 1.00 31.59  ? 166 LYS B N     1 
ATOM   3883 C CA    . LYS B 1 166 ? 128.087 159.892 154.106 1.00 31.59  ? 166 LYS B CA    1 
ATOM   3884 C C     . LYS B 1 166 ? 126.990 159.428 153.160 1.00 31.59  ? 166 LYS B C     1 
ATOM   3885 O O     . LYS B 1 166 ? 125.845 159.867 153.309 1.00 31.59  ? 166 LYS B O     1 
ATOM   3886 C CB    . LYS B 1 166 ? 128.614 161.254 153.653 1.00 31.59  ? 166 LYS B CB    1 
ATOM   3887 C CG    . LYS B 1 166 ? 129.448 161.965 154.702 1.00 31.59  ? 166 LYS B CG    1 
ATOM   3888 C CD    . LYS B 1 166 ? 128.582 162.476 155.837 1.00 31.59  ? 166 LYS B CD    1 
ATOM   3889 C CE    . LYS B 1 166 ? 129.429 163.021 156.973 1.00 31.59  ? 166 LYS B CE    1 
ATOM   3890 N NZ    . LYS B 1 166 ? 128.633 163.880 157.893 1.00 31.59  ? 166 LYS B NZ    1 
ATOM   3891 N N     . ASN B 1 167 ? 127.297 158.564 152.194 1.00 35.07  ? 167 ASN B N     1 
ATOM   3892 C CA    . ASN B 1 167 ? 126.285 158.061 151.277 1.00 35.07  ? 167 ASN B CA    1 
ATOM   3893 C C     . ASN B 1 167 ? 126.054 156.577 151.513 1.00 35.07  ? 167 ASN B C     1 
ATOM   3894 O O     . ASN B 1 167 ? 126.996 155.824 151.772 1.00 35.07  ? 167 ASN B O     1 
ATOM   3895 C CB    . ASN B 1 167 ? 126.679 158.318 149.824 1.00 35.07  ? 167 ASN B CB    1 
ATOM   3896 C CG    . ASN B 1 167 ? 126.924 159.786 149.545 1.00 35.07  ? 167 ASN B CG    1 
ATOM   3897 O OD1   . ASN B 1 167 ? 126.926 160.611 150.456 1.00 35.07  ? 167 ASN B OD1   1 
ATOM   3898 N ND2   . ASN B 1 167 ? 127.115 160.121 148.281 1.00 35.07  ? 167 ASN B ND2   1 
ATOM   3899 N N     . ASN B 1 168 ? 124.794 156.166 151.419 1.00 41.98  ? 168 ASN B N     1 
ATOM   3900 C CA    . ASN B 1 168 ? 124.380 154.828 151.806 1.00 41.98  ? 168 ASN B CA    1 
ATOM   3901 C C     . ASN B 1 168 ? 124.635 153.815 150.691 1.00 41.98  ? 168 ASN B C     1 
ATOM   3902 O O     . ASN B 1 168 ? 124.933 154.159 149.542 1.00 41.98  ? 168 ASN B O     1 
ATOM   3903 C CB    . ASN B 1 168 ? 122.903 154.824 152.210 1.00 41.98  ? 168 ASN B CB    1 
ATOM   3904 C CG    . ASN B 1 168 ? 121.979 155.180 151.062 1.00 41.98  ? 168 ASN B CG    1 
ATOM   3905 O OD1   . ASN B 1 168 ? 121.815 154.410 150.115 1.00 41.98  ? 168 ASN B OD1   1 
ATOM   3906 N ND2   . ASN B 1 168 ? 121.364 156.354 151.143 1.00 41.98  ? 168 ASN B ND2   1 
ATOM   3907 N N     . LEU B 1 169 ? 124.504 152.539 151.062 1.00 44.16  ? 169 LEU B N     1 
ATOM   3908 C CA    . LEU B 1 169 ? 124.818 151.451 150.144 1.00 44.16  ? 169 LEU B CA    1 
ATOM   3909 C C     . LEU B 1 169 ? 123.886 151.446 148.944 1.00 44.16  ? 169 LEU B C     1 
ATOM   3910 O O     . LEU B 1 169 ? 124.318 151.179 147.819 1.00 44.16  ? 169 LEU B O     1 
ATOM   3911 C CB    . LEU B 1 169 ? 124.737 150.112 150.869 1.00 44.16  ? 169 LEU B CB    1 
ATOM   3912 C CG    . LEU B 1 169 ? 125.289 148.935 150.072 1.00 44.16  ? 169 LEU B CG    1 
ATOM   3913 C CD1   . LEU B 1 169 ? 126.797 149.014 150.043 1.00 44.16  ? 169 LEU B CD1   1 
ATOM   3914 C CD2   . LEU B 1 169 ? 124.815 147.619 150.651 1.00 44.16  ? 169 LEU B CD2   1 
ATOM   3915 N N     . LYS B 1 170 ? 122.596 151.707 149.164 1.00 51.97  ? 170 LYS B N     1 
ATOM   3916 C CA    . LYS B 1 170 ? 121.656 151.703 148.050 1.00 51.97  ? 170 LYS B CA    1 
ATOM   3917 C C     . LYS B 1 170 ? 122.005 152.786 147.040 1.00 51.97  ? 170 LYS B C     1 
ATOM   3918 O O     . LYS B 1 170 ? 122.001 152.542 145.827 1.00 51.97  ? 170 LYS B O     1 
ATOM   3919 C CB    . LYS B 1 170 ? 120.229 151.883 148.565 1.00 51.97  ? 170 LYS B CB    1 
ATOM   3920 C CG    . LYS B 1 170 ? 119.162 151.686 147.503 1.00 51.97  ? 170 LYS B CG    1 
ATOM   3921 C CD    . LYS B 1 170 ? 119.249 150.293 146.900 1.00 51.97  ? 170 LYS B CD    1 
ATOM   3922 C CE    . LYS B 1 170 ? 118.908 149.225 147.928 1.00 51.97  ? 170 LYS B CE    1 
ATOM   3923 N NZ    . LYS B 1 170 ? 118.963 147.856 147.347 1.00 51.97  ? 170 LYS B NZ    1 
ATOM   3924 N N     . ARG B 1 171 ? 122.336 153.984 147.524 1.00 46.24  ? 171 ARG B N     1 
ATOM   3925 C CA    . ARG B 1 171 ? 122.714 155.067 146.624 1.00 46.24  ? 171 ARG B CA    1 
ATOM   3926 C C     . ARG B 1 171 ? 124.001 154.740 145.877 1.00 46.24  ? 171 ARG B C     1 
ATOM   3927 O O     . ARG B 1 171 ? 124.114 155.008 144.674 1.00 46.24  ? 171 ARG B O     1 
ATOM   3928 C CB    . ARG B 1 171 ? 122.862 156.370 147.406 1.00 46.24  ? 171 ARG B CB    1 
ATOM   3929 C CG    . ARG B 1 171 ? 123.361 157.532 146.573 1.00 46.24  ? 171 ARG B CG    1 
ATOM   3930 C CD    . ARG B 1 171 ? 122.335 157.934 145.530 1.00 46.24  ? 171 ARG B CD    1 
ATOM   3931 N NE    . ARG B 1 171 ? 122.922 158.741 144.467 1.00 46.24  ? 171 ARG B NE    1 
ATOM   3932 C CZ    . ARG B 1 171 ? 122.339 158.982 143.301 1.00 46.24  ? 171 ARG B CZ    1 
ATOM   3933 N NH1   . ARG B 1 171 ? 121.139 158.503 143.017 1.00 46.24  ? 171 ARG B NH1   1 
ATOM   3934 N NH2   . ARG B 1 171 ? 122.975 159.720 142.398 1.00 46.24  ? 171 ARG B NH2   1 
ATOM   3935 N N     . ILE B 1 172 ? 124.985 154.157 146.568 1.00 41.62  ? 172 ILE B N     1 
ATOM   3936 C CA    . ILE B 1 172 ? 126.246 153.840 145.901 1.00 41.62  ? 172 ILE B CA    1 
ATOM   3937 C C     . ILE B 1 172 ? 126.045 152.752 144.850 1.00 41.62  ? 172 ILE B C     1 
ATOM   3938 O O     . ILE B 1 172 ? 126.613 152.821 143.754 1.00 41.62  ? 172 ILE B O     1 
ATOM   3939 C CB    . ILE B 1 172 ? 127.323 153.451 146.926 1.00 41.62  ? 172 ILE B CB    1 
ATOM   3940 C CG1   . ILE B 1 172 ? 127.554 154.597 147.908 1.00 41.62  ? 172 ILE B CG1   1 
ATOM   3941 C CG2   . ILE B 1 172 ? 128.622 153.121 146.222 1.00 41.62  ? 172 ILE B CG2   1 
ATOM   3942 C CD1   . ILE B 1 172 ? 128.047 155.861 147.258 1.00 41.62  ? 172 ILE B CD1   1 
ATOM   3943 N N     . ILE B 1 173 ? 125.237 151.736 145.156 1.00 51.49  ? 173 ILE B N     1 
ATOM   3944 C CA    . ILE B 1 173 ? 124.954 150.696 144.169 1.00 51.49  ? 173 ILE B CA    1 
ATOM   3945 C C     . ILE B 1 173 ? 124.211 151.283 142.976 1.00 51.49  ? 173 ILE B C     1 
ATOM   3946 O O     . ILE B 1 173 ? 124.468 150.912 141.824 1.00 51.49  ? 173 ILE B O     1 
ATOM   3947 C CB    . ILE B 1 173 ? 124.170 149.536 144.813 1.00 51.49  ? 173 ILE B CB    1 
ATOM   3948 C CG1   . ILE B 1 173 ? 125.040 148.805 145.835 1.00 51.49  ? 173 ILE B CG1   1 
ATOM   3949 C CG2   . ILE B 1 173 ? 123.685 148.559 143.754 1.00 51.49  ? 173 ILE B CG2   1 
ATOM   3950 C CD1   . ILE B 1 173 ? 124.262 147.866 146.728 1.00 51.49  ? 173 ILE B CD1   1 
ATOM   3951 N N     . ARG B 1 174 ? 123.281 152.208 143.229 1.00 58.10  ? 174 ARG B N     1 
ATOM   3952 C CA    . ARG B 1 174 ? 122.581 152.864 142.129 1.00 58.10  ? 174 ARG B CA    1 
ATOM   3953 C C     . ARG B 1 174 ? 123.552 153.632 141.242 1.00 58.10  ? 174 ARG B C     1 
ATOM   3954 O O     . ARG B 1 174 ? 123.451 153.586 140.010 1.00 58.10  ? 174 ARG B O     1 
ATOM   3955 C CB    . ARG B 1 174 ? 121.500 153.795 142.674 1.00 58.10  ? 174 ARG B CB    1 
ATOM   3956 C CG    . ARG B 1 174 ? 120.596 154.384 141.605 1.00 58.10  ? 174 ARG B CG    1 
ATOM   3957 C CD    . ARG B 1 174 ? 119.813 155.577 142.133 1.00 58.10  ? 174 ARG B CD    1 
ATOM   3958 N NE    . ARG B 1 174 ? 119.285 155.348 143.474 1.00 58.10  ? 174 ARG B NE    1 
ATOM   3959 C CZ    . ARG B 1 174 ? 118.257 154.558 143.754 1.00 58.10  ? 174 ARG B CZ    1 
ATOM   3960 N NH1   . ARG B 1 174 ? 117.607 153.905 142.804 1.00 58.10  ? 174 ARG B NH1   1 
ATOM   3961 N NH2   . ARG B 1 174 ? 117.869 154.423 145.018 1.00 58.10  ? 174 ARG B NH2   1 
ATOM   3962 N N     . CYS B 1 175 ? 124.638 154.158 141.816 1.00 58.34  ? 175 CYS B N     1 
ATOM   3963 C CA    . CYS B 1 175 ? 125.665 154.860 140.987 1.00 58.34  ? 175 CYS B CA    1 
ATOM   3964 C C     . CYS B 1 175 ? 126.463 153.887 140.109 1.00 58.34  ? 175 CYS B C     1 
ATOM   3965 O O     . CYS B 1 175 ? 127.143 154.368 139.192 1.00 58.34  ? 175 CYS B O     1 
ATOM   3966 C CB    . CYS B 1 175 ? 126.610 155.702 141.833 1.00 58.34  ? 175 CYS B CB    1 
ATOM   3967 S SG    . CYS B 1 175 ? 125.847 157.250 142.372 1.00 58.34  ? 175 CYS B SG    1 
ATOM   3968 N N     . SER B 1 176 ? 126.400 152.582 140.377 1.00 64.97  ? 176 SER B N     1 
ATOM   3969 C CA    . SER B 1 176 ? 127.228 151.605 139.618 1.00 64.97  ? 176 SER B CA    1 
ATOM   3970 C C     . SER B 1 176 ? 126.375 150.795 138.638 1.00 64.97  ? 176 SER B C     1 
ATOM   3971 O O     . SER B 1 176 ? 126.917 149.860 138.027 1.00 64.97  ? 176 SER B O     1 
ATOM   3972 C CB    . SER B 1 176 ? 127.996 150.711 140.548 1.00 64.97  ? 176 SER B CB    1 
ATOM   3973 O OG    . SER B 1 176 ? 129.028 150.024 139.859 1.00 64.97  ? 176 SER B OG    1 
ATOM   3974 N N     . GLN B 1 177 ? 125.095 151.134 138.498 1.00 82.54  ? 177 GLN B N     1 
ATOM   3975 C CA    . GLN B 1 177 ? 124.201 150.438 137.531 1.00 82.54  ? 177 GLN B CA    1 
ATOM   3976 C C     . GLN B 1 177 ? 124.684 150.671 136.096 1.00 82.54  ? 177 GLN B C     1 
ATOM   3977 O O     . GLN B 1 177 ? 124.543 149.743 135.281 1.00 82.54  ? 177 GLN B O     1 
ATOM   3978 C CB    . GLN B 1 177 ? 122.760 150.930 137.669 1.00 82.54  ? 177 GLN B CB    1 
ATOM   3979 C CG    . GLN B 1 177 ? 122.147 150.661 139.033 1.00 82.54  ? 177 GLN B CG    1 
ATOM   3980 C CD    . GLN B 1 177 ? 120.713 150.204 138.919 1.00 82.54  ? 177 GLN B CD    1 
ATOM   3981 O OE1   . GLN B 1 177 ? 120.174 150.058 137.825 1.00 82.54  ? 177 GLN B OE1   1 
ATOM   3982 N NE2   . GLN B 1 177 ? 120.087 149.962 140.059 1.00 82.54  ? 177 GLN B NE2   1 
ATOM   3983 N N     . ILE B 1 178 ? 125.204 151.864 135.793 1.00 79.43  ? 178 ILE B N     1 
ATOM   3984 C CA    . ILE B 1 178 ? 125.621 152.230 134.404 1.00 79.43  ? 178 ILE B CA    1 
ATOM   3985 C C     . ILE B 1 178 ? 126.717 151.280 133.909 1.00 79.43  ? 178 ILE B C     1 
ATOM   3986 O O     . ILE B 1 178 ? 126.720 150.966 132.704 1.00 79.43  ? 178 ILE B O     1 
ATOM   3987 C CB    . ILE B 1 178 ? 126.054 153.708 134.339 1.00 79.43  ? 178 ILE B CB    1 
ATOM   3988 C CG1   . ILE B 1 178 ? 126.548 154.217 135.697 1.00 79.43  ? 178 ILE B CG1   1 
ATOM   3989 C CG2   . ILE B 1 178 ? 124.928 154.572 133.795 1.00 79.43  ? 178 ILE B CG2   1 
ATOM   3990 C CD1   . ILE B 1 178 ? 128.040 154.087 135.907 1.00 79.43  ? 178 ILE B CD1   1 
ATOM   3991 N N     . MET B 1 179 ? 127.608 150.844 134.799 1.00 93.42  ? 179 MET B N     1 
ATOM   3992 C CA    . MET B 1 179 ? 128.700 149.910 134.421 1.00 93.42  ? 179 MET B CA    1 
ATOM   3993 C C     . MET B 1 179 ? 128.059 148.620 133.907 1.00 93.42  ? 179 MET B C     1 
ATOM   3994 O O     . MET B 1 179 ? 128.704 147.930 133.094 1.00 93.42  ? 179 MET B O     1 
ATOM   3995 C CB    . MET B 1 179 ? 129.575 149.569 135.633 1.00 93.42  ? 179 MET B CB    1 
ATOM   3996 C CG    . MET B 1 179 ? 129.989 150.781 136.450 1.00 93.42  ? 179 MET B CG    1 
ATOM   3997 S SD    . MET B 1 179 ? 131.311 151.766 135.699 1.00 93.42  ? 179 MET B SD    1 
ATOM   3998 C CE    . MET B 1 179 ? 132.741 150.765 136.104 1.00 93.42  ? 179 MET B CE    1 
ATOM   3999 N N     . GLY B 1 180 ? 126.834 148.319 134.347 1.00 95.18  ? 180 GLY B N     1 
ATOM   4000 C CA    . GLY B 1 180 ? 126.181 147.048 133.979 1.00 95.18  ? 180 GLY B CA    1 
ATOM   4001 C C     . GLY B 1 180 ? 126.144 146.112 135.170 1.00 95.18  ? 180 GLY B C     1 
ATOM   4002 O O     . GLY B 1 180 ? 125.641 144.983 135.012 1.00 95.18  ? 180 GLY B O     1 
ATOM   4003 N N     . ARG B 1 181 ? 126.643 146.569 136.325 1.00 91.07  ? 181 ARG B N     1 
ATOM   4004 C CA    . ARG B 1 181 ? 126.571 145.749 137.561 1.00 91.07  ? 181 ARG B CA    1 
ATOM   4005 C C     . ARG B 1 181 ? 125.446 146.304 138.435 1.00 91.07  ? 181 ARG B C     1 
ATOM   4006 O O     . ARG B 1 181 ? 125.584 147.459 138.873 1.00 91.07  ? 181 ARG B O     1 
ATOM   4007 C CB    . ARG B 1 181 ? 127.893 145.844 138.326 1.00 91.07  ? 181 ARG B CB    1 
ATOM   4008 C CG    . ARG B 1 181 ? 129.115 145.363 137.558 1.00 91.07  ? 181 ARG B CG    1 
ATOM   4009 C CD    . ARG B 1 181 ? 129.088 143.865 137.338 1.00 91.07  ? 181 ARG B CD    1 
ATOM   4010 N NE    . ARG B 1 181 ? 130.378 143.317 136.947 1.00 91.07  ? 181 ARG B NE    1 
ATOM   4011 C CZ    . ARG B 1 181 ? 131.219 142.715 137.779 1.00 91.07  ? 181 ARG B CZ    1 
ATOM   4012 N NH1   . ARG B 1 181 ? 132.372 142.246 137.334 1.00 91.07  ? 181 ARG B NH1   1 
ATOM   4013 N NH2   . ARG B 1 181 ? 130.900 142.577 139.053 1.00 91.07  ? 181 ARG B NH2   1 
ATOM   4014 N N     . SER B 1 182 ? 124.406 145.504 138.700 1.00 110.43 ? 182 SER B N     1 
ATOM   4015 C CA    . SER B 1 182 ? 123.249 145.933 139.537 1.00 110.43 ? 182 SER B CA    1 
ATOM   4016 C C     . SER B 1 182 ? 122.244 144.785 139.597 1.00 110.43 ? 182 SER B C     1 
ATOM   4017 O O     . SER B 1 182 ? 122.633 143.680 140.013 1.00 110.43 ? 182 SER B O     1 
ATOM   4018 C CB    . SER B 1 182 ? 122.584 147.176 139.007 1.00 110.43 ? 182 SER B CB    1 
ATOM   4019 O OG    . SER B 1 182 ? 122.218 147.021 137.644 1.00 110.43 ? 182 SER B OG    1 
ATOM   4020 N N     . GLU B 1 183 ? 120.994 145.039 139.204 1.00 122.28 ? 183 GLU B N     1 
ATOM   4021 C CA    . GLU B 1 183 ? 120.009 143.931 139.129 1.00 122.28 ? 183 GLU B CA    1 
ATOM   4022 C C     . GLU B 1 183 ? 120.539 142.949 138.086 1.00 122.28 ? 183 GLU B C     1 
ATOM   4023 O O     . GLU B 1 183 ? 120.426 141.729 138.308 1.00 122.28 ? 183 GLU B O     1 
ATOM   4024 C CB    . GLU B 1 183 ? 118.645 144.460 138.683 1.00 122.28 ? 183 GLU B CB    1 
ATOM   4025 C CG    . GLU B 1 183 ? 118.168 145.669 139.468 1.00 122.28 ? 183 GLU B CG    1 
ATOM   4026 C CD    . GLU B 1 183 ? 118.243 146.989 138.717 1.00 122.28 ? 183 GLU B CD    1 
ATOM   4027 O OE1   . GLU B 1 183 ? 118.888 147.026 137.651 1.00 122.28 ? 183 GLU B OE1   1 
ATOM   4028 O OE2   . GLU B 1 183 ? 117.650 147.975 139.199 1.00 122.28 ? 183 GLU B OE2   1 
ATOM   4029 N N     . GLN B 1 184 ? 121.096 143.475 136.993 1.00 116.92 ? 184 GLN B N     1 
ATOM   4030 C CA    . GLN B 1 184 ? 121.634 142.620 135.906 1.00 116.92 ? 184 GLN B CA    1 
ATOM   4031 C C     . GLN B 1 184 ? 122.819 141.768 136.382 1.00 116.92 ? 184 GLN B C     1 
ATOM   4032 O O     . GLN B 1 184 ? 122.829 140.565 136.049 1.00 116.92 ? 184 GLN B O     1 
ATOM   4033 C CB    . GLN B 1 184 ? 122.070 143.510 134.742 1.00 116.92 ? 184 GLN B CB    1 
ATOM   4034 C CG    . GLN B 1 184 ? 122.751 142.755 133.611 1.00 116.92 ? 184 GLN B CG    1 
ATOM   4035 C CD    . GLN B 1 184 ? 123.437 143.691 132.647 1.00 116.92 ? 184 GLN B CD    1 
ATOM   4036 O OE1   . GLN B 1 184 ? 124.052 143.267 131.671 1.00 116.92 ? 184 GLN B OE1   1 
ATOM   4037 N NE2   . GLN B 1 184 ? 123.339 144.981 132.920 1.00 116.92 ? 184 GLN B NE2   1 
ATOM   4038 N N     . ASP B 1 185 ? 123.762 142.332 137.153 1.00 107.71 ? 185 ASP B N     1 
ATOM   4039 C CA    . ASP B 1 185 ? 124.986 141.545 137.489 1.00 107.71 ? 185 ASP B CA    1 
ATOM   4040 C C     . ASP B 1 185 ? 125.351 141.601 138.977 1.00 107.71 ? 185 ASP B C     1 
ATOM   4041 O O     . ASP B 1 185 ? 125.175 142.669 139.584 1.00 107.71 ? 185 ASP B O     1 
ATOM   4042 C CB    . ASP B 1 185 ? 126.159 141.970 136.601 1.00 107.71 ? 185 ASP B CB    1 
ATOM   4043 C CG    . ASP B 1 185 ? 127.085 140.825 136.226 1.00 107.71 ? 185 ASP B CG    1 
ATOM   4044 O OD1   . ASP B 1 185 ? 126.946 139.738 136.820 1.00 107.71 ? 185 ASP B OD1   1 
ATOM   4045 O OD2   . ASP B 1 185 ? 127.931 141.028 135.333 1.00 107.71 ? 185 ASP B OD2   1 
ATOM   4046 N N     . GLU B 1 186 ? 125.882 140.498 139.523 1.00 96.60  ? 186 GLU B N     1 
ATOM   4047 C CA    . GLU B 1 186 ? 126.337 140.460 140.940 1.00 96.60  ? 186 GLU B CA    1 
ATOM   4048 C C     . GLU B 1 186 ? 127.514 141.424 141.093 1.00 96.60  ? 186 GLU B C     1 
ATOM   4049 O O     . GLU B 1 186 ? 128.378 141.431 140.201 1.00 96.60  ? 186 GLU B O     1 
ATOM   4050 C CB    . GLU B 1 186 ? 126.755 139.036 141.303 1.00 96.60  ? 186 GLU B CB    1 
ATOM   4051 C CG    . GLU B 1 186 ? 127.132 138.866 142.764 1.00 96.60  ? 186 GLU B CG    1 
ATOM   4052 C CD    . GLU B 1 186 ? 127.164 137.425 143.240 1.00 96.60  ? 186 GLU B CD    1 
ATOM   4053 O OE1   . GLU B 1 186 ? 126.630 136.560 142.523 1.00 96.60  ? 186 GLU B OE1   1 
ATOM   4054 O OE2   . GLU B 1 186 ? 127.720 137.174 144.327 1.00 96.60  ? 186 GLU B OE2   1 
ATOM   4055 N N     . LEU B 1 187 ? 127.572 142.176 142.192 1.00 60.40  ? 187 LEU B N     1 
ATOM   4056 C CA    . LEU B 1 187 ? 128.623 143.214 142.318 1.00 60.40  ? 187 LEU B CA    1 
ATOM   4057 C C     . LEU B 1 187 ? 129.761 142.720 143.205 1.00 60.40  ? 187 LEU B C     1 
ATOM   4058 O O     . LEU B 1 187 ? 129.481 141.943 144.123 1.00 60.40  ? 187 LEU B O     1 
ATOM   4059 C CB    . LEU B 1 187 ? 128.003 144.488 142.895 1.00 60.40  ? 187 LEU B CB    1 
ATOM   4060 C CG    . LEU B 1 187 ? 126.908 145.147 142.062 1.00 60.40  ? 187 LEU B CG    1 
ATOM   4061 C CD1   . LEU B 1 187 ? 125.533 144.765 142.586 1.00 60.40  ? 187 LEU B CD1   1 
ATOM   4062 C CD2   . LEU B 1 187 ? 127.072 146.658 142.083 1.00 60.40  ? 187 LEU B CD2   1 
ATOM   4063 N N     . THR B 1 188 ? 131.003 143.075 142.877 1.00 53.33  ? 188 THR B N     1 
ATOM   4064 C CA    . THR B 1 188 ? 132.162 142.760 143.747 1.00 53.33  ? 188 THR B CA    1 
ATOM   4065 C C     . THR B 1 188 ? 132.470 144.060 144.477 1.00 53.33  ? 188 THR B C     1 
ATOM   4066 O O     . THR B 1 188 ? 132.629 145.030 143.779 1.00 53.33  ? 188 THR B O     1 
ATOM   4067 C CB    . THR B 1 188 ? 133.375 142.374 142.898 1.00 53.33  ? 188 THR B CB    1 
ATOM   4068 O OG1   . THR B 1 188 ? 133.950 143.531 142.294 1.00 53.33  ? 188 THR B OG1   1 
ATOM   4069 C CG2   . THR B 1 188 ? 133.032 141.379 141.813 1.00 53.33  ? 188 THR B CG2   1 
ATOM   4070 N N     . ALA B 1 189 ? 132.439 144.095 145.813 1.00 41.86  ? 189 ALA B N     1 
ATOM   4071 C CA    . ALA B 1 189 ? 132.705 145.303 146.586 1.00 41.86  ? 189 ALA B CA    1 
ATOM   4072 C C     . ALA B 1 189 ? 133.602 146.281 145.843 1.00 41.86  ? 189 ALA B C     1 
ATOM   4073 O O     . ALA B 1 189 ? 133.453 147.498 146.018 1.00 41.86  ? 189 ALA B O     1 
ATOM   4074 C CB    . ALA B 1 189 ? 133.331 144.937 147.931 1.00 41.86  ? 189 ALA B CB    1 
ATOM   4075 N N     . ALA B 1 190 ? 134.591 145.805 145.110 1.00 39.97  ? 190 ALA B N     1 
ATOM   4076 C CA    . ALA B 1 190 ? 135.403 146.743 144.311 1.00 39.97  ? 190 ALA B CA    1 
ATOM   4077 C C     . ALA B 1 190 ? 134.470 147.748 143.631 1.00 39.97  ? 190 ALA B C     1 
ATOM   4078 O O     . ALA B 1 190 ? 134.894 148.885 143.451 1.00 39.97  ? 190 ALA B O     1 
ATOM   4079 C CB    . ALA B 1 190 ? 136.263 146.009 143.332 1.00 39.97  ? 190 ALA B CB    1 
ATOM   4080 N N     . GLN B 1 191 ? 133.225 147.361 143.327 1.00 42.81  ? 191 GLN B N     1 
ATOM   4081 C CA    . GLN B 1 191 ? 132.266 148.231 142.588 1.00 42.81  ? 191 GLN B CA    1 
ATOM   4082 C C     . GLN B 1 191 ? 131.608 149.193 143.570 1.00 42.81  ? 191 GLN B C     1 
ATOM   4083 O O     . GLN B 1 191 ? 130.700 149.896 143.132 1.00 42.81  ? 191 GLN B O     1 
ATOM   4084 C CB    . GLN B 1 191 ? 131.182 147.415 141.881 1.00 42.81  ? 191 GLN B CB    1 
ATOM   4085 C CG    . GLN B 1 191 ? 131.699 146.229 141.082 1.00 42.81  ? 191 GLN B CG    1 
ATOM   4086 C CD    . GLN B 1 191 ? 132.371 146.627 139.794 1.00 42.81  ? 191 GLN B CD    1 
ATOM   4087 O OE1   . GLN B 1 191 ? 132.130 147.701 139.251 1.00 42.81  ? 191 GLN B OE1   1 
ATOM   4088 N NE2   . GLN B 1 191 ? 133.215 145.745 139.286 1.00 42.81  ? 191 GLN B NE2   1 
ATOM   4089 N N     . ILE B 1 192 ? 131.935 149.106 144.857 1.00 36.74  ? 192 ILE B N     1 
ATOM   4090 C CA    . ILE B 1 192 ? 131.451 150.094 145.862 1.00 36.74  ? 192 ILE B CA    1 
ATOM   4091 C C     . ILE B 1 192 ? 132.673 150.959 146.156 1.00 36.74  ? 192 ILE B C     1 
ATOM   4092 O O     . ILE B 1 192 ? 132.495 152.060 146.681 1.00 36.74  ? 192 ILE B O     1 
ATOM   4093 C CB    . ILE B 1 192 ? 130.833 149.428 147.103 1.00 36.74  ? 192 ILE B CB    1 
ATOM   4094 C CG1   . ILE B 1 192 ? 129.890 148.286 146.723 1.00 36.74  ? 192 ILE B CG1   1 
ATOM   4095 C CG2   . ILE B 1 192 ? 130.153 150.441 148.006 1.00 36.74  ? 192 ILE B CG2   1 
ATOM   4096 C CD1   . ILE B 1 192 ? 128.713 148.713 145.888 1.00 36.74  ? 192 ILE B CD1   1 
ATOM   4097 N N     . PHE B 1 193 ? 133.881 150.458 145.873 1.00 34.23  ? 193 PHE B N     1 
ATOM   4098 C CA    . PHE B 1 193 ? 135.023 151.372 145.952 1.00 34.23  ? 193 PHE B CA    1 
ATOM   4099 C C     . PHE B 1 193 ? 135.196 152.191 144.675 1.00 34.23  ? 193 PHE B C     1 
ATOM   4100 O O     . PHE B 1 193 ? 135.659 153.335 144.745 1.00 34.23  ? 193 PHE B O     1 
ATOM   4101 C CB    . PHE B 1 193 ? 136.331 150.649 146.301 1.00 34.23  ? 193 PHE B CB    1 
ATOM   4102 C CG    . PHE B 1 193 ? 136.230 149.702 147.463 1.00 34.23  ? 193 PHE B CG    1 
ATOM   4103 C CD1   . PHE B 1 193 ? 135.707 148.442 147.329 1.00 34.23  ? 193 PHE B CD1   1 
ATOM   4104 C CD2   . PHE B 1 193 ? 136.727 150.077 148.697 1.00 34.23  ? 193 PHE B CD2   1 
ATOM   4105 C CE1   . PHE B 1 193 ? 135.617 147.597 148.415 1.00 34.23  ? 193 PHE B CE1   1 
ATOM   4106 C CE2   . PHE B 1 193 ? 136.655 149.234 149.779 1.00 34.23  ? 193 PHE B CE2   1 
ATOM   4107 C CZ    . PHE B 1 193 ? 136.104 147.987 149.635 1.00 34.23  ? 193 PHE B CZ    1 
ATOM   4108 N N     . TYR B 1 194 ? 134.832 151.648 143.509 1.00 35.48  ? 194 TYR B N     1 
ATOM   4109 C CA    . TYR B 1 194 ? 135.009 152.408 142.271 1.00 35.48  ? 194 TYR B CA    1 
ATOM   4110 C C     . TYR B 1 194 ? 134.189 153.692 142.239 1.00 35.48  ? 194 TYR B C     1 
ATOM   4111 O O     . TYR B 1 194 ? 134.775 154.762 141.996 1.00 35.48  ? 194 TYR B O     1 
ATOM   4112 C CB    . TYR B 1 194 ? 134.698 151.532 141.051 1.00 35.48  ? 194 TYR B CB    1 
ATOM   4113 C CG    . TYR B 1 194 ? 135.601 150.336 140.870 1.00 35.48  ? 194 TYR B CG    1 
ATOM   4114 C CD1   . TYR B 1 194 ? 136.906 150.341 141.343 1.00 35.48  ? 194 TYR B CD1   1 
ATOM   4115 C CD2   . TYR B 1 194 ? 135.147 149.200 140.214 1.00 35.48  ? 194 TYR B CD2   1 
ATOM   4116 C CE1   . TYR B 1 194 ? 137.728 149.244 141.175 1.00 35.48  ? 194 TYR B CE1   1 
ATOM   4117 C CE2   . TYR B 1 194 ? 135.959 148.102 140.043 1.00 35.48  ? 194 TYR B CE2   1 
ATOM   4118 C CZ    . TYR B 1 194 ? 137.248 148.127 140.523 1.00 35.48  ? 194 TYR B CZ    1 
ATOM   4119 O OH    . TYR B 1 194 ? 138.055 147.028 140.347 1.00 35.48  ? 194 TYR B OH    1 
ATOM   4120 N N     . PRO B 1 195 ? 132.864 153.679 142.454 1.00 37.39  ? 195 PRO B N     1 
ATOM   4121 C CA    . PRO B 1 195 ? 132.131 154.954 142.435 1.00 37.39  ? 195 PRO B CA    1 
ATOM   4122 C C     . PRO B 1 195 ? 132.612 155.924 143.493 1.00 37.39  ? 195 PRO B C     1 
ATOM   4123 O O     . PRO B 1 195 ? 132.657 157.132 143.242 1.00 37.39  ? 195 PRO B O     1 
ATOM   4124 C CB    . PRO B 1 195 ? 130.676 154.526 142.672 1.00 37.39  ? 195 PRO B CB    1 
ATOM   4125 C CG    . PRO B 1 195 ? 130.628 153.104 142.273 1.00 37.39  ? 195 PRO B CG    1 
ATOM   4126 C CD    . PRO B 1 195 ? 131.949 152.551 142.691 1.00 37.39  ? 195 PRO B CD    1 
ATOM   4127 N N     . CYS B 1 196 ? 132.987 155.423 144.670 1.00 42.11  ? 196 CYS B N     1 
ATOM   4128 C CA    . CYS B 1 196 ? 133.486 156.308 145.715 1.00 42.11  ? 196 CYS B CA    1 
ATOM   4129 C C     . CYS B 1 196 ? 134.800 156.961 145.307 1.00 42.11  ? 196 CYS B C     1 
ATOM   4130 O O     . CYS B 1 196 ? 134.987 158.165 145.513 1.00 42.11  ? 196 CYS B O     1 
ATOM   4131 C CB    . CYS B 1 196 ? 133.645 155.536 147.023 1.00 42.11  ? 196 CYS B CB    1 
ATOM   4132 S SG    . CYS B 1 196 ? 132.082 155.124 147.826 1.00 42.11  ? 196 CYS B SG    1 
ATOM   4133 N N     . MET B 1 197 ? 135.719 156.193 144.713 1.00 36.66  ? 197 MET B N     1 
ATOM   4134 C CA    . MET B 1 197 ? 136.965 156.801 144.257 1.00 36.66  ? 197 MET B CA    1 
ATOM   4135 C C     . MET B 1 197 ? 136.723 157.802 143.135 1.00 36.66  ? 197 MET B C     1 
ATOM   4136 O O     . MET B 1 197 ? 137.334 158.875 143.123 1.00 36.66  ? 197 MET B O     1 
ATOM   4137 C CB    . MET B 1 197 ? 137.971 155.743 143.801 1.00 36.66  ? 197 MET B CB    1 
ATOM   4138 C CG    . MET B 1 197 ? 138.699 155.049 144.935 1.00 36.66  ? 197 MET B CG    1 
ATOM   4139 S SD    . MET B 1 197 ? 139.566 153.554 144.429 1.00 36.66  ? 197 MET B SD    1 
ATOM   4140 C CE    . MET B 1 197 ? 138.379 152.796 143.336 1.00 36.66  ? 197 MET B CE    1 
ATOM   4141 N N     . GLN B 1 198 ? 135.846 157.477 142.183 1.00 39.32  ? 198 GLN B N     1 
ATOM   4142 C CA    . GLN B 1 198 ? 135.598 158.409 141.087 1.00 39.32  ? 198 GLN B CA    1 
ATOM   4143 C C     . GLN B 1 198 ? 134.932 159.684 141.586 1.00 39.32  ? 198 GLN B C     1 
ATOM   4144 O O     . GLN B 1 198 ? 135.216 160.777 141.084 1.00 39.32  ? 198 GLN B O     1 
ATOM   4145 C CB    . GLN B 1 198 ? 134.755 157.745 140.001 1.00 39.32  ? 198 GLN B CB    1 
ATOM   4146 C CG    . GLN B 1 198 ? 135.406 156.522 139.392 1.00 39.32  ? 198 GLN B CG    1 
ATOM   4147 C CD    . GLN B 1 198 ? 134.544 155.877 138.334 1.00 39.32  ? 198 GLN B CD    1 
ATOM   4148 O OE1   . GLN B 1 198 ? 133.801 156.558 137.630 1.00 39.32  ? 198 GLN B OE1   1 
ATOM   4149 N NE2   . GLN B 1 198 ? 134.638 154.559 138.212 1.00 39.32  ? 198 GLN B NE2   1 
ATOM   4150 N N     . CYS B 1 199 ? 134.042 159.568 142.574 1.00 41.21  ? 199 CYS B N     1 
ATOM   4151 C CA    . CYS B 1 199 ? 133.428 160.750 143.164 1.00 41.21  ? 199 CYS B CA    1 
ATOM   4152 C C     . CYS B 1 199 ? 134.426 161.565 143.973 1.00 41.21  ? 199 CYS B C     1 
ATOM   4153 O O     . CYS B 1 199 ? 134.352 162.798 143.976 1.00 41.21  ? 199 CYS B O     1 
ATOM   4154 C CB    . CYS B 1 199 ? 132.242 160.344 144.041 1.00 41.21  ? 199 CYS B CB    1 
ATOM   4155 S SG    . CYS B 1 199 ? 131.661 161.638 145.158 1.00 41.21  ? 199 CYS B SG    1 
ATOM   4156 N N     . ALA B 1 200 ? 135.362 160.906 144.656 1.00 31.19  ? 200 ALA B N     1 
ATOM   4157 C CA    . ALA B 1 200 ? 136.359 161.626 145.434 1.00 31.19  ? 200 ALA B CA    1 
ATOM   4158 C C     . ALA B 1 200 ? 137.469 162.210 144.574 1.00 31.19  ? 200 ALA B C     1 
ATOM   4159 O O     . ALA B 1 200 ? 138.200 163.085 145.046 1.00 31.19  ? 200 ALA B O     1 
ATOM   4160 C CB    . ALA B 1 200 ? 136.961 160.707 146.495 1.00 31.19  ? 200 ALA B CB    1 
ATOM   4161 N N     . ASP B 1 201 ? 137.617 161.738 143.335 1.00 44.83  ? 201 ASP B N     1 
ATOM   4162 C CA    . ASP B 1 201 ? 138.611 162.318 142.436 1.00 44.83  ? 201 ASP B CA    1 
ATOM   4163 C C     . ASP B 1 201 ? 138.330 163.792 142.183 1.00 44.83  ? 201 ASP B C     1 
ATOM   4164 O O     . ASP B 1 201 ? 139.257 164.609 142.118 1.00 44.83  ? 201 ASP B O     1 
ATOM   4165 C CB    . ASP B 1 201 ? 138.636 161.554 141.113 1.00 44.83  ? 201 ASP B CB    1 
ATOM   4166 C CG    . ASP B 1 201 ? 139.187 160.153 141.256 1.00 44.83  ? 201 ASP B CG    1 
ATOM   4167 O OD1   . ASP B 1 201 ? 140.027 159.931 142.150 1.00 44.83  ? 201 ASP B OD1   1 
ATOM   4168 O OD2   . ASP B 1 201 ? 138.776 159.268 140.476 1.00 44.83  ? 201 ASP B OD2   1 
ATOM   4169 N N     . ILE B 1 202 ? 137.053 164.147 142.037 1.00 43.57  ? 202 ILE B N     1 
ATOM   4170 C CA    . ILE B 1 202 ? 136.683 165.524 141.726 1.00 43.57  ? 202 ILE B CA    1 
ATOM   4171 C C     . ILE B 1 202 ? 137.146 166.464 142.831 1.00 43.57  ? 202 ILE B C     1 
ATOM   4172 O O     . ILE B 1 202 ? 137.730 167.522 142.569 1.00 43.57  ? 202 ILE B O     1 
ATOM   4173 C CB    . ILE B 1 202 ? 135.165 165.624 141.497 1.00 43.57  ? 202 ILE B CB    1 
ATOM   4174 C CG1   . ILE B 1 202 ? 134.749 164.706 140.348 1.00 43.57  ? 202 ILE B CG1   1 
ATOM   4175 C CG2   . ILE B 1 202 ? 134.766 167.058 141.220 1.00 43.57  ? 202 ILE B CG2   1 
ATOM   4176 C CD1   . ILE B 1 202 ? 133.280 164.374 140.330 1.00 43.57  ? 202 ILE B CD1   1 
ATOM   4177 N N     . PHE B 1 203 ? 136.897 166.089 144.086 1.00 63.87  ? 203 PHE B N     1 
ATOM   4178 C CA    . PHE B 1 203 ? 137.303 166.921 145.211 1.00 63.87  ? 203 PHE B CA    1 
ATOM   4179 C C     . PHE B 1 203 ? 138.792 166.820 145.513 1.00 63.87  ? 203 PHE B C     1 
ATOM   4180 O O     . PHE B 1 203 ? 139.365 167.777 146.044 1.00 63.87  ? 203 PHE B O     1 
ATOM   4181 C CB    . PHE B 1 203 ? 136.488 166.557 146.451 1.00 63.87  ? 203 PHE B CB    1 
ATOM   4182 C CG    . PHE B 1 203 ? 135.019 166.419 146.185 1.00 63.87  ? 203 PHE B CG    1 
ATOM   4183 C CD1   . PHE B 1 203 ? 134.213 167.538 146.087 1.00 63.87  ? 203 PHE B CD1   1 
ATOM   4184 C CD2   . PHE B 1 203 ? 134.444 165.172 146.022 1.00 63.87  ? 203 PHE B CD2   1 
ATOM   4185 C CE1   . PHE B 1 203 ? 132.863 167.415 145.838 1.00 63.87  ? 203 PHE B CE1   1 
ATOM   4186 C CE2   . PHE B 1 203 ? 133.095 165.043 145.772 1.00 63.87  ? 203 PHE B CE2   1 
ATOM   4187 C CZ    . PHE B 1 203 ? 132.304 166.166 145.681 1.00 63.87  ? 203 PHE B CZ    1 
ATOM   4188 N N     . PHE B 1 204 ? 139.429 165.688 145.200 1.00 44.83  ? 204 PHE B N     1 
ATOM   4189 C CA    . PHE B 1 204 ? 140.879 165.601 145.334 1.00 44.83  ? 204 PHE B CA    1 
ATOM   4190 C C     . PHE B 1 204 ? 141.566 166.565 144.378 1.00 44.83  ? 204 PHE B C     1 
ATOM   4191 O O     . PHE B 1 204 ? 142.515 167.260 144.761 1.00 44.83  ? 204 PHE B O     1 
ATOM   4192 C CB    . PHE B 1 204 ? 141.341 164.163 145.085 1.00 44.83  ? 204 PHE B CB    1 
ATOM   4193 C CG    . PHE B 1 204 ? 142.835 163.979 145.140 1.00 44.83  ? 204 PHE B CG    1 
ATOM   4194 C CD1   . PHE B 1 204 ? 143.616 164.722 146.009 1.00 44.83  ? 204 PHE B CD1   1 
ATOM   4195 C CD2   . PHE B 1 204 ? 143.456 163.059 144.316 1.00 44.83  ? 204 PHE B CD2   1 
ATOM   4196 C CE1   . PHE B 1 204 ? 144.984 164.553 146.052 1.00 44.83  ? 204 PHE B CE1   1 
ATOM   4197 C CE2   . PHE B 1 204 ? 144.823 162.885 144.358 1.00 44.83  ? 204 PHE B CE2   1 
ATOM   4198 C CZ    . PHE B 1 204 ? 145.588 163.632 145.226 1.00 44.83  ? 204 PHE B CZ    1 
ATOM   4199 N N     . LEU B 1 205 ? 141.088 166.637 143.140 1.00 42.22  ? 205 LEU B N     1 
ATOM   4200 C CA    . LEU B 1 205 ? 141.608 167.576 142.160 1.00 42.22  ? 205 LEU B CA    1 
ATOM   4201 C C     . LEU B 1 205 ? 141.059 168.981 142.359 1.00 42.22  ? 205 LEU B C     1 
ATOM   4202 O O     . LEU B 1 205 ? 141.416 169.887 141.598 1.00 42.22  ? 205 LEU B O     1 
ATOM   4203 C CB    . LEU B 1 205 ? 141.292 167.084 140.747 1.00 42.22  ? 205 LEU B CB    1 
ATOM   4204 C CG    . LEU B 1 205 ? 141.838 165.695 140.417 1.00 42.22  ? 205 LEU B CG    1 
ATOM   4205 C CD1   . LEU B 1 205 ? 141.482 165.303 138.999 1.00 42.22  ? 205 LEU B CD1   1 
ATOM   4206 C CD2   . LEU B 1 205 ? 143.339 165.650 140.630 1.00 42.22  ? 205 LEU B CD2   1 
ATOM   4207 N N     . LYS B 1 206 ? 140.203 169.177 143.366 1.00 38.11  ? 206 LYS B N     1 
ATOM   4208 C CA    . LYS B 1 206 ? 139.560 170.464 143.633 1.00 38.11  ? 206 LYS B CA    1 
ATOM   4209 C C     . LYS B 1 206 ? 138.813 170.971 142.406 1.00 38.11  ? 206 LYS B C     1 
ATOM   4210 O O     . LYS B 1 206 ? 138.736 172.175 142.160 1.00 38.11  ? 206 LYS B O     1 
ATOM   4211 C CB    . LYS B 1 206 ? 140.573 171.503 144.122 1.00 38.11  ? 206 LYS B CB    1 
ATOM   4212 C CG    . LYS B 1 206 ? 141.633 170.946 145.059 1.00 38.11  ? 206 LYS B CG    1 
ATOM   4213 C CD    . LYS B 1 206 ? 142.355 172.057 145.801 1.00 38.11  ? 206 LYS B CD    1 
ATOM   4214 C CE    . LYS B 1 206 ? 143.373 171.493 146.777 1.00 38.11  ? 206 LYS B CE    1 
ATOM   4215 N NZ    . LYS B 1 206 ? 144.722 171.374 146.160 1.00 38.11  ? 206 LYS B NZ    1 
ATOM   4216 N N     . ALA B 1 207 ? 138.242 170.045 141.639 1.00 38.22  ? 207 ALA B N     1 
ATOM   4217 C CA    . ALA B 1 207 ? 137.613 170.396 140.375 1.00 38.22  ? 207 ALA B CA    1 
ATOM   4218 C C     . ALA B 1 207 ? 136.347 171.209 140.607 1.00 38.22  ? 207 ALA B C     1 
ATOM   4219 O O     . ALA B 1 207 ? 135.457 170.794 141.356 1.00 38.22  ? 207 ALA B O     1 
ATOM   4220 C CB    . ALA B 1 207 ? 137.290 169.134 139.580 1.00 38.22  ? 207 ALA B CB    1 
ATOM   4221 N N     . ASP B 1 208 ? 136.268 172.369 139.958 1.00 35.99  ? 208 ASP B N     1 
ATOM   4222 C CA    . ASP B 1 208 ? 135.071 173.197 140.013 1.00 35.99  ? 208 ASP B CA    1 
ATOM   4223 C C     . ASP B 1 208 ? 134.078 172.851 138.915 1.00 35.99  ? 208 ASP B C     1 
ATOM   4224 O O     . ASP B 1 208 ? 132.896 173.194 139.027 1.00 35.99  ? 208 ASP B O     1 
ATOM   4225 C CB    . ASP B 1 208 ? 135.449 174.676 139.910 1.00 35.99  ? 208 ASP B CB    1 
ATOM   4226 C CG    . ASP B 1 208 ? 136.497 175.079 140.925 1.00 35.99  ? 208 ASP B CG    1 
ATOM   4227 O OD1   . ASP B 1 208 ? 136.752 174.292 141.859 1.00 35.99  ? 208 ASP B OD1   1 
ATOM   4228 O OD2   . ASP B 1 208 ? 137.066 176.182 140.788 1.00 35.99  ? 208 ASP B OD2   1 
ATOM   4229 N N     . ILE B 1 209 ? 134.534 172.182 137.861 1.00 35.83  ? 209 ILE B N     1 
ATOM   4230 C CA    . ILE B 1 209 ? 133.695 171.776 136.743 1.00 35.83  ? 209 ILE B CA    1 
ATOM   4231 C C     . ILE B 1 209 ? 133.947 170.302 136.467 1.00 35.83  ? 209 ILE B C     1 
ATOM   4232 O O     . ILE B 1 209 ? 135.054 169.796 136.674 1.00 35.83  ? 209 ILE B O     1 
ATOM   4233 C CB    . ILE B 1 209 ? 133.976 172.622 135.480 1.00 35.83  ? 209 ILE B CB    1 
ATOM   4234 C CG1   . ILE B 1 209 ? 133.913 174.114 135.804 1.00 35.83  ? 209 ILE B CG1   1 
ATOM   4235 C CG2   . ILE B 1 209 ? 132.991 172.293 134.377 1.00 35.83  ? 209 ILE B CG2   1 
ATOM   4236 C CD1   . ILE B 1 209 ? 134.161 175.012 134.614 1.00 35.83  ? 209 ILE B CD1   1 
ATOM   4237 N N     . CYS B 1 210 ? 132.912 169.609 136.004 1.00 42.89  ? 210 CYS B N     1 
ATOM   4238 C CA    . CYS B 1 210 ? 133.027 168.223 135.572 1.00 42.89  ? 210 CYS B CA    1 
ATOM   4239 C C     . CYS B 1 210 ? 132.457 168.107 134.170 1.00 42.89  ? 210 CYS B C     1 
ATOM   4240 O O     . CYS B 1 210 ? 131.311 168.500 133.929 1.00 42.89  ? 210 CYS B O     1 
ATOM   4241 C CB    . CYS B 1 210 ? 132.296 167.282 136.528 1.00 42.89  ? 210 CYS B CB    1 
ATOM   4242 S SG    . CYS B 1 210 ? 133.013 167.213 138.174 1.00 42.89  ? 210 CYS B SG    1 
ATOM   4243 N N     . GLN B 1 211 ? 133.255 167.577 133.246 1.00 63.87  ? 211 GLN B N     1 
ATOM   4244 C CA    . GLN B 1 211 ? 132.805 167.320 131.886 1.00 63.87  ? 211 GLN B CA    1 
ATOM   4245 C C     . GLN B 1 211 ? 132.891 165.845 131.520 1.00 63.87  ? 211 GLN B C     1 
ATOM   4246 O O     . GLN B 1 211 ? 133.160 165.510 130.361 1.00 63.87  ? 211 GLN B O     1 
ATOM   4247 C CB    . GLN B 1 211 ? 133.593 168.177 130.896 1.00 63.87  ? 211 GLN B CB    1 
ATOM   4248 C CG    . GLN B 1 211 ? 135.093 168.039 130.999 1.00 63.87  ? 211 GLN B CG    1 
ATOM   4249 C CD    . GLN B 1 211 ? 135.819 168.941 130.028 1.00 63.87  ? 211 GLN B CD    1 
ATOM   4250 O OE1   . GLN B 1 211 ? 135.197 169.623 129.216 1.00 63.87  ? 211 GLN B OE1   1 
ATOM   4251 N NE2   . GLN B 1 211 ? 137.144 168.949 130.105 1.00 63.87  ? 211 GLN B NE2   1 
ATOM   4252 N N     . LEU B 1 212 ? 132.667 164.960 132.487 1.00 54.67  ? 212 LEU B N     1 
ATOM   4253 C CA    . LEU B 1 212 ? 132.639 163.531 132.217 1.00 54.67  ? 212 LEU B CA    1 
ATOM   4254 C C     . LEU B 1 212 ? 131.476 163.192 131.295 1.00 54.67  ? 212 LEU B C     1 
ATOM   4255 O O     . LEU B 1 212 ? 130.496 163.933 131.198 1.00 54.67  ? 212 LEU B O     1 
ATOM   4256 C CB    . LEU B 1 212 ? 132.506 162.753 133.524 1.00 54.67  ? 212 LEU B CB    1 
ATOM   4257 C CG    . LEU B 1 212 ? 133.679 162.843 134.499 1.00 54.67  ? 212 LEU B CG    1 
ATOM   4258 C CD1   . LEU B 1 212 ? 133.330 162.138 135.797 1.00 54.67  ? 212 LEU B CD1   1 
ATOM   4259 C CD2   . LEU B 1 212 ? 134.933 162.247 133.882 1.00 54.67  ? 212 LEU B CD2   1 
ATOM   4260 N N     . GLY B 1 213 ? 131.582 162.055 130.621 1.00 57.93  ? 213 GLY B N     1 
ATOM   4261 C CA    . GLY B 1 213 ? 130.526 161.625 129.730 1.00 57.93  ? 213 GLY B CA    1 
ATOM   4262 C C     . GLY B 1 213 ? 129.260 161.252 130.477 1.00 57.93  ? 213 GLY B C     1 
ATOM   4263 O O     . GLY B 1 213 ? 129.197 161.238 131.707 1.00 57.93  ? 213 GLY B O     1 
ATOM   4264 N N     . MET B 1 214 ? 128.220 160.943 129.700 1.00 67.82  ? 214 MET B N     1 
ATOM   4265 C CA    . MET B 1 214 ? 126.933 160.586 130.288 1.00 67.82  ? 214 MET B CA    1 
ATOM   4266 C C     . MET B 1 214 ? 127.006 159.305 131.108 1.00 67.82  ? 214 MET B C     1 
ATOM   4267 O O     . MET B 1 214 ? 126.103 159.046 131.911 1.00 67.82  ? 214 MET B O     1 
ATOM   4268 C CB    . MET B 1 214 ? 125.876 160.443 129.192 1.00 67.82  ? 214 MET B CB    1 
ATOM   4269 C CG    . MET B 1 214 ? 125.350 161.763 128.655 1.00 67.82  ? 214 MET B CG    1 
ATOM   4270 S SD    . MET B 1 214 ? 123.831 162.294 129.467 1.00 67.82  ? 214 MET B SD    1 
ATOM   4271 C CE    . MET B 1 214 ? 123.867 164.052 129.130 1.00 67.82  ? 214 MET B CE    1 
ATOM   4272 N N     . ASP B 1 215 ? 128.052 158.496 130.920 1.00 70.67  ? 215 ASP B N     1 
ATOM   4273 C CA    . ASP B 1 215 ? 128.202 157.285 131.720 1.00 70.67  ? 215 ASP B CA    1 
ATOM   4274 C C     . ASP B 1 215 ? 128.393 157.611 133.196 1.00 70.67  ? 215 ASP B C     1 
ATOM   4275 O O     . ASP B 1 215 ? 127.818 156.944 134.064 1.00 70.67  ? 215 ASP B O     1 
ATOM   4276 C CB    . ASP B 1 215 ? 129.376 156.454 131.201 1.00 70.67  ? 215 ASP B CB    1 
ATOM   4277 C CG    . ASP B 1 215 ? 129.096 155.831 129.849 1.00 70.67  ? 215 ASP B CG    1 
ATOM   4278 O OD1   . ASP B 1 215 ? 127.915 155.544 129.560 1.00 70.67  ? 215 ASP B OD1   1 
ATOM   4279 O OD2   . ASP B 1 215 ? 130.055 155.628 129.076 1.00 70.67  ? 215 ASP B OD2   1 
ATOM   4280 N N     . GLN B 1 216 ? 129.191 158.634 133.502 1.00 69.89  ? 216 GLN B N     1 
ATOM   4281 C CA    . GLN B 1 216 ? 129.526 158.978 134.878 1.00 69.89  ? 216 GLN B CA    1 
ATOM   4282 C C     . GLN B 1 216 ? 128.777 160.215 135.368 1.00 69.89  ? 216 GLN B C     1 
ATOM   4283 O O     . GLN B 1 216 ? 129.193 160.848 136.346 1.00 69.89  ? 216 GLN B O     1 
ATOM   4284 C CB    . GLN B 1 216 ? 131.037 159.159 135.020 1.00 69.89  ? 216 GLN B CB    1 
ATOM   4285 C CG    . GLN B 1 216 ? 131.806 157.862 134.796 1.00 69.89  ? 216 GLN B CG    1 
ATOM   4286 C CD    . GLN B 1 216 ? 133.303 158.015 134.968 1.00 69.89  ? 216 GLN B CD    1 
ATOM   4287 O OE1   . GLN B 1 216 ? 133.803 159.105 135.237 1.00 69.89  ? 216 GLN B OE1   1 
ATOM   4288 N NE2   . GLN B 1 216 ? 134.030 156.915 134.808 1.00 69.89  ? 216 GLN B NE2   1 
ATOM   4289 N N     . ARG B 1 217 ? 127.671 160.567 134.709 1.00 56.25  ? 217 ARG B N     1 
ATOM   4290 C CA    . ARG B 1 217 ? 126.802 161.612 135.237 1.00 56.25  ? 217 ARG B CA    1 
ATOM   4291 C C     . ARG B 1 217 ? 126.236 161.209 136.593 1.00 56.25  ? 217 ARG B C     1 
ATOM   4292 O O     . ARG B 1 217 ? 125.950 162.066 137.436 1.00 56.25  ? 217 ARG B O     1 
ATOM   4293 C CB    . ARG B 1 217 ? 125.677 161.909 134.247 1.00 56.25  ? 217 ARG B CB    1 
ATOM   4294 C CG    . ARG B 1 217 ? 124.830 163.114 134.614 1.00 56.25  ? 217 ARG B CG    1 
ATOM   4295 C CD    . ARG B 1 217 ? 123.511 163.111 133.864 1.00 56.25  ? 217 ARG B CD    1 
ATOM   4296 N NE    . ARG B 1 217 ? 122.671 164.241 134.241 1.00 56.25  ? 217 ARG B NE    1 
ATOM   4297 C CZ    . ARG B 1 217 ? 121.783 164.218 135.226 1.00 56.25  ? 217 ARG B CZ    1 
ATOM   4298 N NH1   . ARG B 1 217 ? 121.590 163.133 135.957 1.00 56.25  ? 217 ARG B NH1   1 
ATOM   4299 N NH2   . ARG B 1 217 ? 121.073 165.313 135.484 1.00 56.25  ? 217 ARG B NH2   1 
ATOM   4300 N N     . LYS B 1 218 ? 126.072 159.904 136.821 1.00 58.74  ? 218 LYS B N     1 
ATOM   4301 C CA    . LYS B 1 218 ? 125.654 159.426 138.135 1.00 58.74  ? 218 LYS B CA    1 
ATOM   4302 C C     . LYS B 1 218 ? 126.682 159.796 139.197 1.00 58.74  ? 218 LYS B C     1 
ATOM   4303 O O     . LYS B 1 218 ? 126.331 160.278 140.279 1.00 58.74  ? 218 LYS B O     1 
ATOM   4304 C CB    . LYS B 1 218 ? 125.440 157.914 138.092 1.00 58.74  ? 218 LYS B CB    1 
ATOM   4305 C CG    . LYS B 1 218 ? 124.372 157.470 137.110 1.00 58.74  ? 218 LYS B CG    1 
ATOM   4306 C CD    . LYS B 1 218 ? 123.846 156.087 137.450 1.00 58.74  ? 218 LYS B CD    1 
ATOM   4307 C CE    . LYS B 1 218 ? 122.541 155.802 136.727 1.00 58.74  ? 218 LYS B CE    1 
ATOM   4308 N NZ    . LYS B 1 218 ? 121.800 154.667 137.343 1.00 58.74  ? 218 LYS B NZ    1 
ATOM   4309 N N     . VAL B 1 219 ? 127.966 159.589 138.895 1.00 50.86  ? 219 VAL B N     1 
ATOM   4310 C CA    . VAL B 1 219 ? 129.021 159.967 139.828 1.00 50.86  ? 219 VAL B CA    1 
ATOM   4311 C C     . VAL B 1 219 ? 129.078 161.479 139.992 1.00 50.86  ? 219 VAL B C     1 
ATOM   4312 O O     . VAL B 1 219 ? 129.356 161.981 141.087 1.00 50.86  ? 219 VAL B O     1 
ATOM   4313 C CB    . VAL B 1 219 ? 130.370 159.391 139.363 1.00 50.86  ? 219 VAL B CB    1 
ATOM   4314 C CG1   . VAL B 1 219 ? 131.521 160.029 140.121 1.00 50.86  ? 219 VAL B CG1   1 
ATOM   4315 C CG2   . VAL B 1 219 ? 130.385 157.889 139.554 1.00 50.86  ? 219 VAL B CG2   1 
ATOM   4316 N N     . ASN B 1 220 ? 128.815 162.231 138.923 1.00 47.40  ? 220 ASN B N     1 
ATOM   4317 C CA    . ASN B 1 220 ? 128.773 163.685 139.048 1.00 47.40  ? 220 ASN B CA    1 
ATOM   4318 C C     . ASN B 1 220 ? 127.662 164.133 139.996 1.00 47.40  ? 220 ASN B C     1 
ATOM   4319 O O     . ASN B 1 220 ? 127.873 165.008 140.845 1.00 47.40  ? 220 ASN B O     1 
ATOM   4320 C CB    . ASN B 1 220 ? 128.598 164.317 137.669 1.00 47.40  ? 220 ASN B CB    1 
ATOM   4321 C CG    . ASN B 1 220 ? 129.842 164.193 136.811 1.00 47.40  ? 220 ASN B CG    1 
ATOM   4322 O OD1   . ASN B 1 220 ? 130.954 164.075 137.325 1.00 47.40  ? 220 ASN B OD1   1 
ATOM   4323 N ND2   . ASN B 1 220 ? 129.660 164.219 135.497 1.00 47.40  ? 220 ASN B ND2   1 
ATOM   4324 N N     . VAL B 1 221 ? 126.476 163.534 139.874 1.00 51.35  ? 221 VAL B N     1 
ATOM   4325 C CA    . VAL B 1 221 ? 125.372 163.863 140.772 1.00 51.35  ? 221 VAL B CA    1 
ATOM   4326 C C     . VAL B 1 221 ? 125.703 163.442 142.200 1.00 51.35  ? 221 VAL B C     1 
ATOM   4327 O O     . VAL B 1 221 ? 125.346 164.129 143.168 1.00 51.35  ? 221 VAL B O     1 
ATOM   4328 C CB    . VAL B 1 221 ? 124.071 163.210 140.271 1.00 51.35  ? 221 VAL B CB    1 
ATOM   4329 C CG1   . VAL B 1 221 ? 122.976 163.312 141.319 1.00 51.35  ? 221 VAL B CG1   1 
ATOM   4330 C CG2   . VAL B 1 221 ? 123.625 163.854 138.969 1.00 51.35  ? 221 VAL B CG2   1 
ATOM   4331 N N     . LEU B 1 222 ? 126.384 162.305 142.352 1.00 44.05  ? 222 LEU B N     1 
ATOM   4332 C CA    . LEU B 1 222 ? 126.809 161.862 143.675 1.00 44.05  ? 222 LEU B CA    1 
ATOM   4333 C C     . LEU B 1 222 ? 127.767 162.866 144.304 1.00 44.05  ? 222 LEU B C     1 
ATOM   4334 O O     . LEU B 1 222 ? 127.668 163.175 145.498 1.00 44.05  ? 222 LEU B O     1 
ATOM   4335 C CB    . LEU B 1 222 ? 127.468 160.490 143.570 1.00 44.05  ? 222 LEU B CB    1 
ATOM   4336 C CG    . LEU B 1 222 ? 127.518 159.661 144.846 1.00 44.05  ? 222 LEU B CG    1 
ATOM   4337 C CD1   . LEU B 1 222 ? 126.110 159.497 145.370 1.00 44.05  ? 222 LEU B CD1   1 
ATOM   4338 C CD2   . LEU B 1 222 ? 128.159 158.316 144.579 1.00 44.05  ? 222 LEU B CD2   1 
ATOM   4339 N N     . ALA B 1 223 ? 128.704 163.383 143.511 1.00 41.35  ? 223 ALA B N     1 
ATOM   4340 C CA    . ALA B 1 223 ? 129.607 164.416 144.001 1.00 41.35  ? 223 ALA B CA    1 
ATOM   4341 C C     . ALA B 1 223 ? 128.843 165.678 144.373 1.00 41.35  ? 223 ALA B C     1 
ATOM   4342 O O     . ALA B 1 223 ? 129.171 166.342 145.362 1.00 41.35  ? 223 ALA B O     1 
ATOM   4343 C CB    . ALA B 1 223 ? 130.672 164.722 142.950 1.00 41.35  ? 223 ALA B CB    1 
ATOM   4344 N N     . ARG B 1 224 ? 127.824 166.028 143.588 1.00 40.69  ? 224 ARG B N     1 
ATOM   4345 C CA    . ARG B 1 224 ? 127.014 167.201 143.909 1.00 40.69  ? 224 ARG B CA    1 
ATOM   4346 C C     . ARG B 1 224 ? 126.323 167.040 145.259 1.00 40.69  ? 224 ARG B C     1 
ATOM   4347 O O     . ARG B 1 224 ? 126.334 167.955 146.094 1.00 40.69  ? 224 ARG B O     1 
ATOM   4348 C CB    . ARG B 1 224 ? 125.984 167.445 142.806 1.00 40.69  ? 224 ARG B CB    1 
ATOM   4349 C CG    . ARG B 1 224 ? 126.565 168.037 141.537 1.00 40.69  ? 224 ARG B CG    1 
ATOM   4350 C CD    . ARG B 1 224 ? 125.468 168.551 140.611 1.00 40.69  ? 224 ARG B CD    1 
ATOM   4351 N NE    . ARG B 1 224 ? 124.960 169.870 140.980 1.00 40.69  ? 224 ARG B NE    1 
ATOM   4352 C CZ    . ARG B 1 224 ? 125.697 170.961 141.151 1.00 40.69  ? 224 ARG B CZ    1 
ATOM   4353 N NH1   . ARG B 1 224 ? 127.001 170.964 140.929 1.00 40.69  ? 224 ARG B NH1   1 
ATOM   4354 N NH2   . ARG B 1 224 ? 125.105 172.088 141.534 1.00 40.69  ? 224 ARG B NH2   1 
ATOM   4355 N N     . GLU B 1 225 ? 125.717 165.875 145.497 1.00 47.39  ? 225 GLU B N     1 
ATOM   4356 C CA    . GLU B 1 225 ? 125.012 165.692 146.762 1.00 47.39  ? 225 GLU B CA    1 
ATOM   4357 C C     . GLU B 1 225 ? 125.984 165.574 147.932 1.00 47.39  ? 225 GLU B C     1 
ATOM   4358 O O     . GLU B 1 225 ? 125.661 166.002 149.044 1.00 47.39  ? 225 GLU B O     1 
ATOM   4359 C CB    . GLU B 1 225 ? 124.073 164.484 146.702 1.00 47.39  ? 225 GLU B CB    1 
ATOM   4360 C CG    . GLU B 1 225 ? 124.724 163.150 146.434 1.00 47.39  ? 225 GLU B CG    1 
ATOM   4361 C CD    . GLU B 1 225 ? 123.712 162.023 146.375 1.00 47.39  ? 225 GLU B CD    1 
ATOM   4362 O OE1   . GLU B 1 225 ? 122.835 162.058 145.487 1.00 47.39  ? 225 GLU B OE1   1 
ATOM   4363 O OE2   . GLU B 1 225 ? 123.789 161.105 147.218 1.00 47.39  ? 225 GLU B OE2   1 
ATOM   4364 N N     . TYR B 1 226 ? 127.182 165.030 147.705 1.00 49.99  ? 226 TYR B N     1 
ATOM   4365 C CA    . TYR B 1 226 ? 128.201 165.064 148.751 1.00 49.99  ? 226 TYR B CA    1 
ATOM   4366 C C     . TYR B 1 226 ? 128.620 166.495 149.063 1.00 49.99  ? 226 TYR B C     1 
ATOM   4367 O O     . TYR B 1 226 ? 128.852 166.846 150.226 1.00 49.99  ? 226 TYR B O     1 
ATOM   4368 C CB    . TYR B 1 226 ? 129.414 164.237 148.337 1.00 49.99  ? 226 TYR B CB    1 
ATOM   4369 C CG    . TYR B 1 226 ? 130.597 164.353 149.275 1.00 49.99  ? 226 TYR B CG    1 
ATOM   4370 C CD1   . TYR B 1 226 ? 130.643 163.638 150.461 1.00 49.99  ? 226 TYR B CD1   1 
ATOM   4371 C CD2   . TYR B 1 226 ? 131.670 165.176 148.969 1.00 49.99  ? 226 TYR B CD2   1 
ATOM   4372 C CE1   . TYR B 1 226 ? 131.724 163.734 151.311 1.00 49.99  ? 226 TYR B CE1   1 
ATOM   4373 C CE2   . TYR B 1 226 ? 132.753 165.283 149.815 1.00 49.99  ? 226 TYR B CE2   1 
ATOM   4374 C CZ    . TYR B 1 226 ? 132.775 164.559 150.983 1.00 49.99  ? 226 TYR B CZ    1 
ATOM   4375 O OH    . TYR B 1 226 ? 133.853 164.665 151.830 1.00 49.99  ? 226 TYR B OH    1 
ATOM   4376 N N     . CYS B 1 227 ? 128.740 167.330 148.029 1.00 45.09  ? 227 CYS B N     1 
ATOM   4377 C CA    . CYS B 1 227 ? 129.066 168.734 148.240 1.00 45.09  ? 227 CYS B CA    1 
ATOM   4378 C C     . CYS B 1 227 ? 127.977 169.428 149.044 1.00 45.09  ? 227 CYS B C     1 
ATOM   4379 O O     . CYS B 1 227 ? 128.262 170.297 149.876 1.00 45.09  ? 227 CYS B O     1 
ATOM   4380 C CB    . CYS B 1 227 ? 129.270 169.423 146.892 1.00 45.09  ? 227 CYS B CB    1 
ATOM   4381 S SG    . CYS B 1 227 ? 129.747 171.154 146.997 1.00 45.09  ? 227 CYS B SG    1 
ATOM   4382 N N     . ASP B 1 228 ? 126.718 169.061 148.797 1.00 45.10  ? 228 ASP B N     1 
ATOM   4383 C CA    . ASP B 1 228 ? 125.630 169.549 149.641 1.00 45.10  ? 228 ASP B CA    1 
ATOM   4384 C C     . ASP B 1 228 ? 125.787 169.058 151.077 1.00 45.10  ? 228 ASP B C     1 
ATOM   4385 O O     . ASP B 1 228 ? 125.550 169.811 152.029 1.00 45.10  ? 228 ASP B O     1 
ATOM   4386 C CB    . ASP B 1 228 ? 124.280 169.110 149.073 1.00 45.10  ? 228 ASP B CB    1 
ATOM   4387 C CG    . ASP B 1 228 ? 123.874 169.909 147.853 1.00 45.10  ? 228 ASP B CG    1 
ATOM   4388 O OD1   . ASP B 1 228 ? 124.245 171.098 147.770 1.00 45.10  ? 228 ASP B OD1   1 
ATOM   4389 O OD2   . ASP B 1 228 ? 123.180 169.349 146.978 1.00 45.10  ? 228 ASP B OD2   1 
ATOM   4390 N N     . ASP B 1 229 ? 126.180 167.794 151.247 1.00 44.25  ? 229 ASP B N     1 
ATOM   4391 C CA    . ASP B 1 229 ? 126.313 167.219 152.583 1.00 44.25  ? 229 ASP B CA    1 
ATOM   4392 C C     . ASP B 1 229 ? 127.397 167.918 153.394 1.00 44.25  ? 229 ASP B C     1 
ATOM   4393 O O     . ASP B 1 229 ? 127.223 168.165 154.593 1.00 44.25  ? 229 ASP B O     1 
ATOM   4394 C CB    . ASP B 1 229 ? 126.610 165.722 152.484 1.00 44.25  ? 229 ASP B CB    1 
ATOM   4395 C CG    . ASP B 1 229 ? 125.363 164.871 152.590 1.00 44.25  ? 229 ASP B CG    1 
ATOM   4396 O OD1   . ASP B 1 229 ? 124.298 165.416 152.946 1.00 44.25  ? 229 ASP B OD1   1 
ATOM   4397 O OD2   . ASP B 1 229 ? 125.446 163.655 152.317 1.00 44.25  ? 229 ASP B OD2   1 
ATOM   4398 N N     . ILE B 1 230 ? 128.523 168.245 152.762 1.00 44.01  ? 230 ILE B N     1 
ATOM   4399 C CA    . ILE B 1 230 ? 129.685 168.754 153.486 1.00 44.01  ? 230 ILE B CA    1 
ATOM   4400 C C     . ILE B 1 230 ? 129.577 170.273 153.589 1.00 44.01  ? 230 ILE B C     1 
ATOM   4401 O O     . ILE B 1 230 ? 130.465 170.943 154.129 1.00 44.01  ? 230 ILE B O     1 
ATOM   4402 C CB    . ILE B 1 230 ? 130.985 168.295 152.797 1.00 44.01  ? 230 ILE B CB    1 
ATOM   4403 C CG1   . ILE B 1 230 ? 131.012 166.774 152.752 1.00 44.01  ? 230 ILE B CG1   1 
ATOM   4404 C CG2   . ILE B 1 230 ? 132.226 168.723 153.566 1.00 44.01  ? 230 ILE B CG2   1 
ATOM   4405 C CD1   . ILE B 1 230 ? 130.991 166.126 154.118 1.00 44.01  ? 230 ILE B CD1   1 
ATOM   4406 N N     . LYS B 1 231 ? 128.462 170.823 153.106 1.00 58.97  ? 231 LYS B N     1 
ATOM   4407 C CA    . LYS B 1 231 ? 128.165 172.250 153.223 1.00 58.97  ? 231 LYS B CA    1 
ATOM   4408 C C     . LYS B 1 231 ? 129.249 173.097 152.551 1.00 58.97  ? 231 LYS B C     1 
ATOM   4409 O O     . LYS B 1 231 ? 129.967 173.870 153.190 1.00 58.97  ? 231 LYS B O     1 
ATOM   4410 C CB    . LYS B 1 231 ? 127.980 172.650 154.693 1.00 58.97  ? 231 LYS B CB    1 
ATOM   4411 C CG    . LYS B 1 231 ? 127.304 173.997 154.903 1.00 58.97  ? 231 LYS B CG    1 
ATOM   4412 C CD    . LYS B 1 231 ? 125.827 173.938 154.558 1.00 58.97  ? 231 LYS B CD    1 
ATOM   4413 C CE    . LYS B 1 231 ? 125.073 173.048 155.532 1.00 58.97  ? 231 LYS B CE    1 
ATOM   4414 N NZ    . LYS B 1 231 ? 123.598 173.153 155.356 1.00 58.97  ? 231 LYS B NZ    1 
ATOM   4415 N N     . ARG B 1 232 ? 129.365 172.925 151.238 1.00 46.47  ? 232 ARG B N     1 
ATOM   4416 C CA    . ARG B 1 232 ? 130.217 173.760 150.403 1.00 46.47  ? 232 ARG B CA    1 
ATOM   4417 C C     . ARG B 1 232 ? 129.332 174.595 149.489 1.00 46.47  ? 232 ARG B C     1 
ATOM   4418 O O     . ARG B 1 232 ? 128.408 174.066 148.863 1.00 46.47  ? 232 ARG B O     1 
ATOM   4419 C CB    . ARG B 1 232 ? 131.186 172.917 149.573 1.00 46.47  ? 232 ARG B CB    1 
ATOM   4420 C CG    . ARG B 1 232 ? 132.465 172.523 150.284 1.00 46.47  ? 232 ARG B CG    1 
ATOM   4421 C CD    . ARG B 1 232 ? 132.841 171.089 149.950 1.00 46.47  ? 232 ARG B CD    1 
ATOM   4422 N NE    . ARG B 1 232 ? 132.855 170.857 148.511 1.00 46.47  ? 232 ARG B NE    1 
ATOM   4423 C CZ    . ARG B 1 232 ? 133.922 171.007 147.738 1.00 46.47  ? 232 ARG B CZ    1 
ATOM   4424 N NH1   . ARG B 1 232 ? 135.088 171.384 148.235 1.00 46.47  ? 232 ARG B NH1   1 
ATOM   4425 N NH2   . ARG B 1 232 ? 133.815 170.773 146.433 1.00 46.47  ? 232 ARG B NH2   1 
ATOM   4426 N N     . LYS B 1 233 ? 129.614 175.892 149.415 1.00 48.30  ? 233 LYS B N     1 
ATOM   4427 C CA    . LYS B 1 233 ? 128.809 176.812 148.625 1.00 48.30  ? 233 LYS B CA    1 
ATOM   4428 C C     . LYS B 1 233 ? 129.139 176.764 147.138 1.00 48.30  ? 233 LYS B C     1 
ATOM   4429 O O     . LYS B 1 233 ? 128.376 177.304 146.330 1.00 48.30  ? 233 LYS B O     1 
ATOM   4430 C CB    . LYS B 1 233 ? 128.982 178.246 149.154 1.00 48.30  ? 233 LYS B CB    1 
ATOM   4431 C CG    . LYS B 1 233 ? 127.958 179.300 148.675 1.00 48.30  ? 233 LYS B CG    1 
ATOM   4432 C CD    . LYS B 1 233 ? 126.473 178.874 148.640 1.00 48.30  ? 233 LYS B CD    1 
ATOM   4433 C CE    . LYS B 1 233 ? 126.017 178.051 149.848 1.00 48.30  ? 233 LYS B CE    1 
ATOM   4434 N NZ    . LYS B 1 233 ? 124.534 178.017 149.972 1.00 48.30  ? 233 LYS B NZ    1 
ATOM   4435 N N     . ASN B 1 234 ? 130.239 176.121 146.755 1.00 41.83  ? 234 ASN B N     1 
ATOM   4436 C CA    . ASN B 1 234 ? 130.667 176.035 145.360 1.00 41.83  ? 234 ASN B CA    1 
ATOM   4437 C C     . ASN B 1 234 ? 130.533 174.583 144.909 1.00 41.83  ? 234 ASN B C     1 
ATOM   4438 O O     . ASN B 1 234 ? 131.487 173.806 144.983 1.00 41.83  ? 234 ASN B O     1 
ATOM   4439 C CB    . ASN B 1 234 ? 132.097 176.546 145.195 1.00 41.83  ? 234 ASN B CB    1 
ATOM   4440 C CG    . ASN B 1 234 ? 132.150 177.992 144.747 1.00 41.83  ? 234 ASN B CG    1 
ATOM   4441 O OD1   . ASN B 1 234 ? 131.153 178.711 144.810 1.00 41.83  ? 234 ASN B OD1   1 
ATOM   4442 N ND2   . ASN B 1 234 ? 133.319 178.427 144.291 1.00 41.83  ? 234 ASN B ND2   1 
ATOM   4443 N N     . LYS B 1 235 ? 129.344 174.224 144.438 1.00 35.30  ? 235 LYS B N     1 
ATOM   4444 C CA    . LYS B 1 235 ? 129.124 172.884 143.927 1.00 35.30  ? 235 LYS B CA    1 
ATOM   4445 C C     . LYS B 1 235 ? 129.854 172.701 142.596 1.00 35.30  ? 235 LYS B C     1 
ATOM   4446 O O     . LYS B 1 235 ? 130.018 173.655 141.832 1.00 35.30  ? 235 LYS B O     1 
ATOM   4447 C CB    . LYS B 1 235 ? 127.632 172.621 143.746 1.00 35.30  ? 235 LYS B CB    1 
ATOM   4448 C CG    . LYS B 1 235 ? 126.923 172.174 145.014 1.00 35.30  ? 235 LYS B CG    1 
ATOM   4449 C CD    . LYS B 1 235 ? 125.414 172.178 144.837 1.00 35.30  ? 235 LYS B CD    1 
ATOM   4450 C CE    . LYS B 1 235 ? 124.887 170.776 144.579 1.00 35.30  ? 235 LYS B CE    1 
ATOM   4451 N NZ    . LYS B 1 235 ? 123.422 170.673 144.826 1.00 35.30  ? 235 LYS B NZ    1 
ATOM   4452 N N     . PRO B 1 236 ? 130.309 171.483 142.298 1.00 31.65  ? 236 PRO B N     1 
ATOM   4453 C CA    . PRO B 1 236 ? 131.009 171.243 141.027 1.00 31.65  ? 236 PRO B CA    1 
ATOM   4454 C C     . PRO B 1 236 ? 130.027 171.219 139.864 1.00 31.65  ? 236 PRO B C     1 
ATOM   4455 O O     . PRO B 1 236 ? 129.073 170.438 139.855 1.00 31.65  ? 236 PRO B O     1 
ATOM   4456 C CB    . PRO B 1 236 ? 131.669 169.877 141.241 1.00 31.65  ? 236 PRO B CB    1 
ATOM   4457 C CG    . PRO B 1 236 ? 130.792 169.199 142.231 1.00 31.65  ? 236 PRO B CG    1 
ATOM   4458 C CD    . PRO B 1 236 ? 130.283 170.280 143.147 1.00 31.65  ? 236 PRO B CD    1 
ATOM   4459 N N     . ILE B 1 237 ? 130.267 172.086 138.878 1.00 30.96  ? 237 ILE B N     1 
ATOM   4460 C CA    . ILE B 1 237 ? 129.390 172.166 137.717 1.00 30.96  ? 237 ILE B CA    1 
ATOM   4461 C C     . ILE B 1 237 ? 129.557 170.917 136.865 1.00 30.96  ? 237 ILE B C     1 
ATOM   4462 O O     . ILE B 1 237 ? 130.649 170.340 136.780 1.00 30.96  ? 237 ILE B O     1 
ATOM   4463 C CB    . ILE B 1 237 ? 129.694 173.434 136.902 1.00 30.96  ? 237 ILE B CB    1 
ATOM   4464 C CG1   . ILE B 1 237 ? 129.807 174.644 137.825 1.00 30.96  ? 237 ILE B CG1   1 
ATOM   4465 C CG2   . ILE B 1 237 ? 128.601 173.676 135.884 1.00 30.96  ? 237 ILE B CG2   1 
ATOM   4466 C CD1   . ILE B 1 237 ? 128.534 174.960 138.556 1.00 30.96  ? 237 ILE B CD1   1 
ATOM   4467 N N     . ILE B 1 238 ? 128.471 170.489 136.227 1.00 32.12  ? 238 ILE B N     1 
ATOM   4468 C CA    . ILE B 1 238 ? 128.467 169.313 135.365 1.00 32.12  ? 238 ILE B CA    1 
ATOM   4469 C C     . ILE B 1 238 ? 128.306 169.781 133.926 1.00 32.12  ? 238 ILE B C     1 
ATOM   4470 O O     . ILE B 1 238 ? 127.424 170.594 133.627 1.00 32.12  ? 238 ILE B O     1 
ATOM   4471 C CB    . ILE B 1 238 ? 127.353 168.327 135.754 1.00 32.12  ? 238 ILE B CB    1 
ATOM   4472 C CG1   . ILE B 1 238 ? 127.349 168.076 137.265 1.00 32.12  ? 238 ILE B CG1   1 
ATOM   4473 C CG2   . ILE B 1 238 ? 127.514 167.018 135.002 1.00 32.12  ? 238 ILE B CG2   1 
ATOM   4474 C CD1   . ILE B 1 238 ? 128.713 167.804 137.866 1.00 32.12  ? 238 ILE B CD1   1 
ATOM   4475 N N     . LEU B 1 239 ? 129.169 169.274 133.033 1.00 30.88  ? 239 LEU B N     1 
ATOM   4476 C CA    . LEU B 1 239 ? 129.186 169.658 131.623 1.00 30.88  ? 239 LEU B CA    1 
ATOM   4477 C C     . LEU B 1 239 ? 129.274 168.390 130.770 1.00 30.88  ? 239 LEU B C     1 
ATOM   4478 O O     . LEU B 1 239 ? 130.123 168.268 129.891 1.00 30.88  ? 239 LEU B O     1 
ATOM   4479 C CB    . LEU B 1 239 ? 130.340 170.611 131.308 1.00 30.88  ? 239 LEU B CB    1 
ATOM   4480 C CG    . LEU B 1 239 ? 130.136 172.092 131.613 1.00 30.88  ? 239 LEU B CG    1 
ATOM   4481 C CD1   . LEU B 1 239 ? 131.393 172.862 131.273 1.00 30.88  ? 239 LEU B CD1   1 
ATOM   4482 C CD2   . LEU B 1 239 ? 128.950 172.633 130.842 1.00 30.88  ? 239 LEU B CD2   1 
ATOM   4483 N N     . SER B 1 240 ? 128.396 167.432 131.057 1.00 36.54  ? 240 SER B N     1 
ATOM   4484 C CA    . SER B 1 240 ? 128.468 166.125 130.415 1.00 36.54  ? 240 SER B CA    1 
ATOM   4485 C C     . SER B 1 240 ? 128.479 166.247 128.896 1.00 36.54  ? 240 SER B C     1 
ATOM   4486 O O     . SER B 1 240 ? 127.580 166.839 128.295 1.00 36.54  ? 240 SER B O     1 
ATOM   4487 C CB    . SER B 1 240 ? 127.291 165.258 130.860 1.00 36.54  ? 240 SER B CB    1 
ATOM   4488 O OG    . SER B 1 240 ? 127.341 165.010 132.254 1.00 36.54  ? 240 SER B OG    1 
ATOM   4489 N N     . HIS B 1 241 ? 129.513 165.679 128.279 1.00 45.98  ? 241 HIS B N     1 
ATOM   4490 C CA    . HIS B 1 241 ? 129.630 165.667 126.829 1.00 45.98  ? 241 HIS B CA    1 
ATOM   4491 C C     . HIS B 1 241 ? 128.547 164.790 126.217 1.00 45.98  ? 241 HIS B C     1 
ATOM   4492 O O     . HIS B 1 241 ? 128.160 163.761 126.778 1.00 45.98  ? 241 HIS B O     1 
ATOM   4493 C CB    . HIS B 1 241 ? 131.003 165.153 126.395 1.00 45.98  ? 241 HIS B CB    1 
ATOM   4494 C CG    . HIS B 1 241 ? 132.146 165.986 126.882 1.00 45.98  ? 241 HIS B CG    1 
ATOM   4495 N ND1   . HIS B 1 241 ? 133.415 165.476 127.055 1.00 45.98  ? 241 HIS B ND1   1 
ATOM   4496 C CD2   . HIS B 1 241 ? 132.214 167.291 127.233 1.00 45.98  ? 241 HIS B CD2   1 
ATOM   4497 C CE1   . HIS B 1 241 ? 134.215 166.432 127.491 1.00 45.98  ? 241 HIS B CE1   1 
ATOM   4498 N NE2   . HIS B 1 241 ? 133.511 167.543 127.608 1.00 45.98  ? 241 HIS B NE2   1 
ATOM   4499 N N     . HIS B 1 242 ? 128.058 165.205 125.053 1.00 49.07  ? 242 HIS B N     1 
ATOM   4500 C CA    . HIS B 1 242 ? 127.043 164.421 124.370 1.00 49.07  ? 242 HIS B CA    1 
ATOM   4501 C C     . HIS B 1 242 ? 127.653 163.120 123.860 1.00 49.07  ? 242 HIS B C     1 
ATOM   4502 O O     . HIS B 1 242 ? 128.686 163.113 123.188 1.00 49.07  ? 242 HIS B O     1 
ATOM   4503 C CB    . HIS B 1 242 ? 126.441 165.217 123.212 1.00 49.07  ? 242 HIS B CB    1 
ATOM   4504 C CG    . HIS B 1 242 ? 125.510 164.424 122.349 1.00 49.07  ? 242 HIS B CG    1 
ATOM   4505 N ND1   . HIS B 1 242 ? 125.286 164.723 121.023 1.00 49.07  ? 242 HIS B ND1   1 
ATOM   4506 C CD2   . HIS B 1 242 ? 124.722 163.359 122.632 1.00 49.07  ? 242 HIS B CD2   1 
ATOM   4507 C CE1   . HIS B 1 242 ? 124.414 163.866 120.522 1.00 49.07  ? 242 HIS B CE1   1 
ATOM   4508 N NE2   . HIS B 1 242 ? 124.057 163.028 121.478 1.00 49.07  ? 242 HIS B NE2   1 
ATOM   4509 N N     . MET B 1 243 ? 127.002 162.009 124.192 1.00 62.75  ? 243 MET B N     1 
ATOM   4510 C CA    . MET B 1 243 ? 127.487 160.684 123.812 1.00 62.75  ? 243 MET B CA    1 
ATOM   4511 C C     . MET B 1 243 ? 127.251 160.492 122.320 1.00 62.75  ? 243 MET B C     1 
ATOM   4512 O O     . MET B 1 243 ? 126.109 160.452 121.857 1.00 62.75  ? 243 MET B O     1 
ATOM   4513 C CB    . MET B 1 243 ? 126.803 159.598 124.634 1.00 62.75  ? 243 MET B CB    1 
ATOM   4514 C CG    . MET B 1 243 ? 127.577 158.293 124.676 1.00 62.75  ? 243 MET B CG    1 
ATOM   4515 S SD    . MET B 1 243 ? 128.840 158.274 125.962 1.00 62.75  ? 243 MET B SD    1 
ATOM   4516 C CE    . MET B 1 243 ? 127.841 157.983 127.417 1.00 62.75  ? 243 MET B CE    1 
ATOM   4517 N N     . LEU B 1 244 ? 128.339 160.378 121.571 1.00 56.30  ? 244 LEU B N     1 
ATOM   4518 C CA    . LEU B 1 244 ? 128.243 160.192 120.133 1.00 56.30  ? 244 LEU B CA    1 
ATOM   4519 C C     . LEU B 1 244 ? 127.630 158.830 119.822 1.00 56.30  ? 244 LEU B C     1 
ATOM   4520 O O     . LEU B 1 244 ? 128.125 157.803 120.301 1.00 56.30  ? 244 LEU B O     1 
ATOM   4521 C CB    . LEU B 1 244 ? 129.630 160.293 119.501 1.00 56.30  ? 244 LEU B CB    1 
ATOM   4522 C CG    . LEU B 1 244 ? 129.762 160.193 117.984 1.00 56.30  ? 244 LEU B CG    1 
ATOM   4523 C CD1   . LEU B 1 244 ? 129.032 161.330 117.329 1.00 56.30  ? 244 LEU B CD1   1 
ATOM   4524 C CD2   . LEU B 1 244 ? 131.219 160.218 117.580 1.00 56.30  ? 244 LEU B CD2   1 
ATOM   4525 N N     . PRO B 1 245 ? 126.562 158.777 119.034 1.00 57.02  ? 245 PRO B N     1 
ATOM   4526 C CA    . PRO B 1 245 ? 126.024 157.479 118.622 1.00 57.02  ? 245 PRO B CA    1 
ATOM   4527 C C     . PRO B 1 245 ? 126.963 156.787 117.649 1.00 57.02  ? 245 PRO B C     1 
ATOM   4528 O O     . PRO B 1 245 ? 127.743 157.419 116.934 1.00 57.02  ? 245 PRO B O     1 
ATOM   4529 C CB    . PRO B 1 245 ? 124.685 157.821 117.958 1.00 57.02  ? 245 PRO B CB    1 
ATOM   4530 C CG    . PRO B 1 245 ? 124.668 159.297 117.770 1.00 57.02  ? 245 PRO B CG    1 
ATOM   4531 C CD    . PRO B 1 245 ? 125.885 159.909 118.384 1.00 57.02  ? 245 PRO B CD    1 
ATOM   4532 N N     . GLY B 1 246 ? 126.882 155.461 117.637 1.00 53.79  ? 246 GLY B N     1 
ATOM   4533 C CA    . GLY B 1 246 ? 127.715 154.685 116.747 1.00 53.79  ? 246 GLY B CA    1 
ATOM   4534 C C     . GLY B 1 246 ? 127.381 154.931 115.290 1.00 53.79  ? 246 GLY B C     1 
ATOM   4535 O O     . GLY B 1 246 ? 126.277 155.339 114.930 1.00 53.79  ? 246 GLY B O     1 
ATOM   4536 N N     . LEU B 1 247 ? 128.372 154.687 114.433 1.00 52.58  ? 247 LEU B N     1 
ATOM   4537 C CA    . LEU B 1 247 ? 128.179 154.877 113.003 1.00 52.58  ? 247 LEU B CA    1 
ATOM   4538 C C     . LEU B 1 247 ? 127.147 153.924 112.420 1.00 52.58  ? 247 LEU B C     1 
ATOM   4539 O O     . LEU B 1 247 ? 126.527 154.253 111.404 1.00 52.58  ? 247 LEU B O     1 
ATOM   4540 C CB    . LEU B 1 247 ? 129.506 154.712 112.263 1.00 52.58  ? 247 LEU B CB    1 
ATOM   4541 C CG    . LEU B 1 247 ? 130.604 155.714 112.616 1.00 52.58  ? 247 LEU B CG    1 
ATOM   4542 C CD1   . LEU B 1 247 ? 131.963 155.071 112.452 1.00 52.58  ? 247 LEU B CD1   1 
ATOM   4543 C CD2   . LEU B 1 247 ? 130.497 156.957 111.756 1.00 52.58  ? 247 LEU B CD2   1 
ATOM   4544 N N     . GLN B 1 248 ? 126.949 152.760 113.030 1.00 59.67  ? 248 GLN B N     1 
ATOM   4545 C CA    . GLN B 1 248 ? 125.912 151.845 112.584 1.00 59.67  ? 248 GLN B CA    1 
ATOM   4546 C C     . GLN B 1 248 ? 124.570 152.227 113.195 1.00 59.67  ? 248 GLN B C     1 
ATOM   4547 O O     . GLN B 1 248 ? 124.501 152.892 114.232 1.00 59.67  ? 248 GLN B O     1 
ATOM   4548 C CB    . GLN B 1 248 ? 126.268 150.403 112.952 1.00 59.67  ? 248 GLN B CB    1 
ATOM   4549 C CG    . GLN B 1 248 ? 127.702 149.966 112.622 1.00 59.67  ? 248 GLN B CG    1 
ATOM   4550 C CD    . GLN B 1 248 ? 128.104 150.123 111.155 1.00 59.67  ? 248 GLN B CD    1 
ATOM   4551 O OE1   . GLN B 1 248 ? 127.322 150.562 110.312 1.00 59.67  ? 248 GLN B OE1   1 
ATOM   4552 N NE2   . GLN B 1 248 ? 129.343 149.755 110.852 1.00 59.67  ? 248 GLN B NE2   1 
ATOM   4553 N N     . GLN B 1 249 ? 123.497 151.797 112.536 1.00 69.09  ? 249 GLN B N     1 
ATOM   4554 C CA    . GLN B 1 249 ? 122.155 152.160 112.970 1.00 69.09  ? 249 GLN B CA    1 
ATOM   4555 C C     . GLN B 1 249 ? 121.839 151.554 114.332 1.00 69.09  ? 249 GLN B C     1 
ATOM   4556 O O     . GLN B 1 249 ? 122.145 150.390 114.602 1.00 69.09  ? 249 GLN B O     1 
ATOM   4557 C CB    . GLN B 1 249 ? 121.126 151.700 111.934 1.00 69.09  ? 249 GLN B CB    1 
ATOM   4558 C CG    . GLN B 1 249 ? 119.703 152.189 112.178 1.00 69.09  ? 249 GLN B CG    1 
ATOM   4559 C CD    . GLN B 1 249 ? 118.920 151.295 113.120 1.00 69.09  ? 249 GLN B CD    1 
ATOM   4560 O OE1   . GLN B 1 249 ? 119.158 150.089 113.192 1.00 69.09  ? 249 GLN B OE1   1 
ATOM   4561 N NE2   . GLN B 1 249 ? 117.980 151.884 113.850 1.00 69.09  ? 249 GLN B NE2   1 
ATOM   4562 N N     . GLY B 1 250 ? 121.222 152.360 115.196 1.00 76.12  ? 250 GLY B N     1 
ATOM   4563 C CA    . GLY B 1 250 ? 120.718 151.909 116.472 1.00 76.12  ? 250 GLY B CA    1 
ATOM   4564 C C     . GLY B 1 250 ? 121.702 151.991 117.622 1.00 76.12  ? 250 GLY B C     1 
ATOM   4565 O O     . GLY B 1 250 ? 121.293 151.879 118.782 1.00 76.12  ? 250 GLY B O     1 
ATOM   4566 N N     . GLN B 1 251 ? 122.987 152.185 117.334 1.00 74.98  ? 251 GLN B N     1 
ATOM   4567 C CA    . GLN B 1 251 ? 123.987 152.241 118.393 1.00 74.98  ? 251 GLN B CA    1 
ATOM   4568 C C     . GLN B 1 251 ? 124.006 153.615 119.048 1.00 74.98  ? 251 GLN B C     1 
ATOM   4569 O O     . GLN B 1 251 ? 124.826 154.468 118.692 1.00 74.98  ? 251 GLN B O     1 
ATOM   4570 C CB    . GLN B 1 251 ? 125.370 151.889 117.842 1.00 74.98  ? 251 GLN B CB    1 
ATOM   4571 C CG    . GLN B 1 251 ? 125.373 150.699 116.895 1.00 74.98  ? 251 GLN B CG    1 
ATOM   4572 C CD    . GLN B 1 251 ? 124.791 149.449 117.525 1.00 74.98  ? 251 GLN B CD    1 
ATOM   4573 O OE1   . GLN B 1 251 ? 125.003 149.177 118.707 1.00 74.98  ? 251 GLN B OE1   1 
ATOM   4574 N NE2   . GLN B 1 251 ? 124.048 148.681 116.737 1.00 74.98  ? 251 GLN B NE2   1 
ATOM   4575 N N     . GLU B 1 252 ? 123.105 153.839 120.007 1.00 74.47  ? 252 GLU B N     1 
ATOM   4576 C CA    . GLU B 1 252 ? 123.056 155.129 120.687 1.00 74.47  ? 252 GLU B CA    1 
ATOM   4577 C C     . GLU B 1 252 ? 124.286 155.345 121.559 1.00 74.47  ? 252 GLU B C     1 
ATOM   4578 O O     . GLU B 1 252 ? 124.673 156.488 121.827 1.00 74.47  ? 252 GLU B O     1 
ATOM   4579 C CB    . GLU B 1 252 ? 121.782 155.235 121.525 1.00 74.47  ? 252 GLU B CB    1 
ATOM   4580 C CG    . GLU B 1 252 ? 120.500 155.261 120.711 1.00 74.47  ? 252 GLU B CG    1 
ATOM   4581 C CD    . GLU B 1 252 ? 119.263 155.385 121.578 1.00 74.47  ? 252 GLU B CD    1 
ATOM   4582 O OE1   . GLU B 1 252 ? 119.370 155.161 122.802 1.00 74.47  ? 252 GLU B OE1   1 
ATOM   4583 O OE2   . GLU B 1 252 ? 118.186 155.709 121.038 1.00 74.47  ? 252 GLU B OE2   1 
ATOM   4584 N N     . LYS B 1 253 ? 124.911 154.263 122.011 1.00 71.52  ? 253 LYS B N     1 
ATOM   4585 C CA    . LYS B 1 253 ? 126.085 154.339 122.869 1.00 71.52  ? 253 LYS B CA    1 
ATOM   4586 C C     . LYS B 1 253 ? 127.341 154.152 122.028 1.00 71.52  ? 253 LYS B C     1 
ATOM   4587 O O     . LYS B 1 253 ? 127.404 153.247 121.189 1.00 71.52  ? 253 LYS B O     1 
ATOM   4588 C CB    . LYS B 1 253 ? 126.021 153.284 123.976 1.00 71.52  ? 253 LYS B CB    1 
ATOM   4589 C CG    . LYS B 1 253 ? 127.364 152.964 124.616 1.00 71.52  ? 253 LYS B CG    1 
ATOM   4590 C CD    . LYS B 1 253 ? 127.874 154.130 125.448 1.00 71.52  ? 253 LYS B CD    1 
ATOM   4591 C CE    . LYS B 1 253 ? 129.196 153.795 126.116 1.00 71.52  ? 253 LYS B CE    1 
ATOM   4592 N NZ    . LYS B 1 253 ? 129.893 155.015 126.606 1.00 71.52  ? 253 LYS B NZ    1 
ATOM   4593 N N     . MET B 1 254 ? 128.330 155.013 122.252 1.00 69.17  ? 254 MET B N     1 
ATOM   4594 C CA    . MET B 1 254 ? 129.588 154.920 121.527 1.00 69.17  ? 254 MET B CA    1 
ATOM   4595 C C     . MET B 1 254 ? 130.356 153.687 121.993 1.00 69.17  ? 254 MET B C     1 
ATOM   4596 O O     . MET B 1 254 ? 130.673 153.553 123.179 1.00 69.17  ? 254 MET B O     1 
ATOM   4597 C CB    . MET B 1 254 ? 130.418 156.184 121.758 1.00 69.17  ? 254 MET B CB    1 
ATOM   4598 C CG    . MET B 1 254 ? 131.903 156.066 121.441 1.00 69.17  ? 254 MET B CG    1 
ATOM   4599 S SD    . MET B 1 254 ? 132.334 155.268 119.879 1.00 69.17  ? 254 MET B SD    1 
ATOM   4600 C CE    . MET B 1 254 ? 131.241 156.111 118.730 1.00 69.17  ? 254 MET B CE    1 
ATOM   4601 N N     . SER B 1 255 ? 130.656 152.788 121.060 1.00 70.31  ? 255 SER B N     1 
ATOM   4602 C CA    . SER B 1 255 ? 131.316 151.524 121.368 1.00 70.31  ? 255 SER B CA    1 
ATOM   4603 C C     . SER B 1 255 ? 132.750 151.566 120.857 1.00 70.31  ? 255 SER B C     1 
ATOM   4604 O O     . SER B 1 255 ? 132.979 151.608 119.644 1.00 70.31  ? 255 SER B O     1 
ATOM   4605 C CB    . SER B 1 255 ? 130.559 150.350 120.748 1.00 70.31  ? 255 SER B CB    1 
ATOM   4606 O OG    . SER B 1 255 ? 131.209 149.121 121.025 1.00 70.31  ? 255 SER B OG    1 
ATOM   4607 N N     . LYS B 1 256 ? 133.709 151.551 121.781 1.00 62.66  ? 256 LYS B N     1 
ATOM   4608 C CA    . LYS B 1 256 ? 135.123 151.510 121.436 1.00 62.66  ? 256 LYS B CA    1 
ATOM   4609 C C     . LYS B 1 256 ? 135.687 150.095 121.413 1.00 62.66  ? 256 LYS B C     1 
ATOM   4610 O O     . LYS B 1 256 ? 136.876 149.922 121.125 1.00 62.66  ? 256 LYS B O     1 
ATOM   4611 C CB    . LYS B 1 256 ? 135.934 152.365 122.416 1.00 62.66  ? 256 LYS B CB    1 
ATOM   4612 C CG    . LYS B 1 256 ? 135.802 151.940 123.867 1.00 62.66  ? 256 LYS B CG    1 
ATOM   4613 C CD    . LYS B 1 256 ? 136.445 152.951 124.799 1.00 62.66  ? 256 LYS B CD    1 
ATOM   4614 C CE    . LYS B 1 256 ? 137.864 153.278 124.367 1.00 62.66  ? 256 LYS B CE    1 
ATOM   4615 N NZ    . LYS B 1 256 ? 138.461 154.369 125.188 1.00 62.66  ? 256 LYS B NZ    1 
ATOM   4616 N N     . SER B 1 257 ? 134.870 149.085 121.710 1.00 75.42  ? 257 SER B N     1 
ATOM   4617 C CA    . SER B 1 257 ? 135.319 147.700 121.685 1.00 75.42  ? 257 SER B CA    1 
ATOM   4618 C C     . SER B 1 257 ? 134.988 146.987 120.382 1.00 75.42  ? 257 SER B C     1 
ATOM   4619 O O     . SER B 1 257 ? 135.526 145.902 120.135 1.00 75.42  ? 257 SER B O     1 
ATOM   4620 C CB    . SER B 1 257 ? 134.703 146.922 122.854 1.00 75.42  ? 257 SER B CB    1 
ATOM   4621 O OG    . SER B 1 257 ? 134.961 147.569 124.088 1.00 75.42  ? 257 SER B OG    1 
ATOM   4622 N N     . ASP B 1 258 ? 134.124 147.565 119.551 1.00 77.27  ? 258 ASP B N     1 
ATOM   4623 C CA    . ASP B 1 258 ? 133.756 146.980 118.266 1.00 77.27  ? 258 ASP B CA    1 
ATOM   4624 C C     . ASP B 1 258 ? 134.342 147.830 117.147 1.00 77.27  ? 258 ASP B C     1 
ATOM   4625 O O     . ASP B 1 258 ? 133.854 148.942 116.892 1.00 77.27  ? 258 ASP B O     1 
ATOM   4626 C CB    . ASP B 1 258 ? 132.234 146.887 118.131 1.00 77.27  ? 258 ASP B CB    1 
ATOM   4627 C CG    . ASP B 1 258 ? 131.797 146.351 116.781 1.00 77.27  ? 258 ASP B CG    1 
ATOM   4628 O OD1   . ASP B 1 258 ? 132.587 145.626 116.139 1.00 77.27  ? 258 ASP B OD1   1 
ATOM   4629 O OD2   . ASP B 1 258 ? 130.662 146.656 116.360 1.00 77.27  ? 258 ASP B OD2   1 
ATOM   4630 N N     . PRO B 1 259 ? 135.385 147.362 116.447 1.00 71.37  ? 259 PRO B N     1 
ATOM   4631 C CA    . PRO B 1 259 ? 136.012 148.147 115.375 1.00 71.37  ? 259 PRO B CA    1 
ATOM   4632 C C     . PRO B 1 259 ? 135.219 148.137 114.069 1.00 71.37  ? 259 PRO B C     1 
ATOM   4633 O O     . PRO B 1 259 ? 135.778 147.987 112.981 1.00 71.37  ? 259 PRO B O     1 
ATOM   4634 C CB    . PRO B 1 259 ? 137.374 147.469 115.215 1.00 71.37  ? 259 PRO B CB    1 
ATOM   4635 C CG    . PRO B 1 259 ? 137.106 146.048 115.566 1.00 71.37  ? 259 PRO B CG    1 
ATOM   4636 C CD    . PRO B 1 259 ? 136.085 146.086 116.675 1.00 71.37  ? 259 PRO B CD    1 
ATOM   4637 N N     . SER B 1 260 ? 133.902 148.297 114.181 1.00 71.11  ? 260 SER B N     1 
ATOM   4638 C CA    . SER B 1 260 ? 133.041 148.423 113.015 1.00 71.11  ? 260 SER B CA    1 
ATOM   4639 C C     . SER B 1 260 ? 131.993 149.514 113.167 1.00 71.11  ? 260 SER B C     1 
ATOM   4640 O O     . SER B 1 260 ? 131.380 149.898 112.166 1.00 71.11  ? 260 SER B O     1 
ATOM   4641 C CB    . SER B 1 260 ? 132.345 147.086 112.713 1.00 71.11  ? 260 SER B CB    1 
ATOM   4642 O OG    . SER B 1 260 ? 131.421 146.750 113.733 1.00 71.11  ? 260 SER B OG    1 
ATOM   4643 N N     . SER B 1 261 ? 131.769 150.027 114.379 1.00 62.68  ? 261 SER B N     1 
ATOM   4644 C CA    . SER B 1 261 ? 130.746 151.035 114.626 1.00 62.68  ? 261 SER B CA    1 
ATOM   4645 C C     . SER B 1 261 ? 131.340 152.320 115.188 1.00 62.68  ? 261 SER B C     1 
ATOM   4646 O O     . SER B 1 261 ? 130.617 153.113 115.797 1.00 62.68  ? 261 SER B O     1 
ATOM   4647 C CB    . SER B 1 261 ? 129.674 150.494 115.576 1.00 62.68  ? 261 SER B CB    1 
ATOM   4648 O OG    . SER B 1 261 ? 128.907 151.546 116.133 1.00 62.68  ? 261 SER B OG    1 
ATOM   4649 N N     . SER B 1 262 ? 132.638 152.541 115.002 1.00 47.47  ? 262 SER B N     1 
ATOM   4650 C CA    . SER B 1 262 ? 133.289 153.733 115.521 1.00 47.47  ? 262 SER B CA    1 
ATOM   4651 C C     . SER B 1 262 ? 134.584 153.964 114.761 1.00 47.47  ? 262 SER B C     1 
ATOM   4652 O O     . SER B 1 262 ? 135.389 153.043 114.601 1.00 47.47  ? 262 SER B O     1 
ATOM   4653 C CB    . SER B 1 262 ? 133.581 153.606 117.019 1.00 47.47  ? 262 SER B CB    1 
ATOM   4654 O OG    . SER B 1 262 ? 132.397 153.361 117.756 1.00 47.47  ? 262 SER B OG    1 
ATOM   4655 N N     . VAL B 1 263 ? 134.780 155.193 114.302 1.00 38.49  ? 263 VAL B N     1 
ATOM   4656 C CA    . VAL B 1 263 ? 136.033 155.569 113.660 1.00 38.49  ? 263 VAL B CA    1 
ATOM   4657 C C     . VAL B 1 263 ? 137.100 155.714 114.734 1.00 38.49  ? 263 VAL B C     1 
ATOM   4658 O O     . VAL B 1 263 ? 136.881 156.368 115.759 1.00 38.49  ? 263 VAL B O     1 
ATOM   4659 C CB    . VAL B 1 263 ? 135.867 156.867 112.855 1.00 38.49  ? 263 VAL B CB    1 
ATOM   4660 C CG1   . VAL B 1 263 ? 137.216 157.508 112.591 1.00 38.49  ? 263 VAL B CG1   1 
ATOM   4661 C CG2   . VAL B 1 263 ? 135.150 156.587 111.549 1.00 38.49  ? 263 VAL B CG2   1 
ATOM   4662 N N     . PHE B 1 264 ? 138.245 155.080 114.521 1.00 42.06  ? 264 PHE B N     1 
ATOM   4663 C CA    . PHE B 1 264 ? 139.369 155.172 115.437 1.00 42.06  ? 264 PHE B CA    1 
ATOM   4664 C C     . PHE B 1 264 ? 140.470 156.007 114.801 1.00 42.06  ? 264 PHE B C     1 
ATOM   4665 O O     . PHE B 1 264 ? 140.753 155.870 113.607 1.00 42.06  ? 264 PHE B O     1 
ATOM   4666 C CB    . PHE B 1 264 ? 139.889 153.783 115.809 1.00 42.06  ? 264 PHE B CB    1 
ATOM   4667 C CG    . PHE B 1 264 ? 138.885 152.945 116.547 1.00 42.06  ? 264 PHE B CG    1 
ATOM   4668 C CD1   . PHE B 1 264 ? 138.698 153.106 117.909 1.00 42.06  ? 264 PHE B CD1   1 
ATOM   4669 C CD2   . PHE B 1 264 ? 138.123 152.003 115.880 1.00 42.06  ? 264 PHE B CD2   1 
ATOM   4670 C CE1   . PHE B 1 264 ? 137.774 152.342 118.591 1.00 42.06  ? 264 PHE B CE1   1 
ATOM   4671 C CE2   . PHE B 1 264 ? 137.198 151.235 116.558 1.00 42.06  ? 264 PHE B CE2   1 
ATOM   4672 C CZ    . PHE B 1 264 ? 137.023 151.404 117.915 1.00 42.06  ? 264 PHE B CZ    1 
ATOM   4673 N N     . MET B 1 265 ? 141.081 156.880 115.602 1.00 38.72  ? 265 MET B N     1 
ATOM   4674 C CA    . MET B 1 265 ? 142.047 157.827 115.061 1.00 38.72  ? 265 MET B CA    1 
ATOM   4675 C C     . MET B 1 265 ? 143.304 157.149 114.532 1.00 38.72  ? 265 MET B C     1 
ATOM   4676 O O     . MET B 1 265 ? 144.070 157.782 113.798 1.00 38.72  ? 265 MET B O     1 
ATOM   4677 C CB    . MET B 1 265 ? 142.414 158.867 116.118 1.00 38.72  ? 265 MET B CB    1 
ATOM   4678 C CG    . MET B 1 265 ? 141.256 159.774 116.486 1.00 38.72  ? 265 MET B CG    1 
ATOM   4679 S SD    . MET B 1 265 ? 141.651 160.953 117.778 1.00 38.72  ? 265 MET B SD    1 
ATOM   4680 C CE    . MET B 1 265 ? 142.755 162.027 116.880 1.00 38.72  ? 265 MET B CE    1 
ATOM   4681 N N     . GLU B 1 266 ? 143.536 155.890 114.887 1.00 43.44  ? 266 GLU B N     1 
ATOM   4682 C CA    . GLU B 1 266 ? 144.668 155.134 114.371 1.00 43.44  ? 266 GLU B CA    1 
ATOM   4683 C C     . GLU B 1 266 ? 144.372 154.457 113.039 1.00 43.44  ? 266 GLU B C     1 
ATOM   4684 O O     . GLU B 1 266 ? 145.265 153.818 112.475 1.00 43.44  ? 266 GLU B O     1 
ATOM   4685 C CB    . GLU B 1 266 ? 145.104 154.084 115.396 1.00 43.44  ? 266 GLU B CB    1 
ATOM   4686 C CG    . GLU B 1 266 ? 143.991 153.143 115.815 1.00 43.44  ? 266 GLU B CG    1 
ATOM   4687 C CD    . GLU B 1 266 ? 144.392 152.240 116.961 1.00 43.44  ? 266 GLU B CD    1 
ATOM   4688 O OE1   . GLU B 1 266 ? 145.555 152.322 117.406 1.00 43.44  ? 266 GLU B OE1   1 
ATOM   4689 O OE2   . GLU B 1 266 ? 143.544 151.444 117.414 1.00 43.44  ? 266 GLU B OE2   1 
ATOM   4690 N N     . ASP B 1 267 ? 143.151 154.580 112.525 1.00 45.26  ? 267 ASP B N     1 
ATOM   4691 C CA    . ASP B 1 267 ? 142.789 153.919 111.281 1.00 45.26  ? 267 ASP B CA    1 
ATOM   4692 C C     . ASP B 1 267 ? 143.429 154.617 110.084 1.00 45.26  ? 267 ASP B C     1 
ATOM   4693 O O     . ASP B 1 267 ? 143.756 155.806 110.118 1.00 45.26  ? 267 ASP B O     1 
ATOM   4694 C CB    . ASP B 1 267 ? 141.271 153.885 111.108 1.00 45.26  ? 267 ASP B CB    1 
ATOM   4695 C CG    . ASP B 1 267 ? 140.622 152.765 111.892 1.00 45.26  ? 267 ASP B CG    1 
ATOM   4696 O OD1   . ASP B 1 267 ? 141.357 151.968 112.510 1.00 45.26  ? 267 ASP B OD1   1 
ATOM   4697 O OD2   . ASP B 1 267 ? 139.376 152.677 111.884 1.00 45.26  ? 267 ASP B OD2   1 
ATOM   4698 N N     . GLU B 1 268 ? 143.603 153.850 109.011 1.00 50.71  ? 268 GLU B N     1 
ATOM   4699 C CA    . GLU B 1 268 ? 144.149 154.370 107.770 1.00 50.71  ? 268 GLU B CA    1 
ATOM   4700 C C     . GLU B 1 268 ? 143.102 155.206 107.039 1.00 50.71  ? 268 GLU B C     1 
ATOM   4701 O O     . GLU B 1 268 ? 141.920 155.220 107.389 1.00 50.71  ? 268 GLU B O     1 
ATOM   4702 C CB    . GLU B 1 268 ? 144.637 153.227 106.881 1.00 50.71  ? 268 GLU B CB    1 
ATOM   4703 C CG    . GLU B 1 268 ? 145.804 152.442 107.457 1.00 50.71  ? 268 GLU B CG    1 
ATOM   4704 C CD    . GLU B 1 268 ? 147.074 153.263 107.543 1.00 50.71  ? 268 GLU B CD    1 
ATOM   4705 O OE1   . GLU B 1 268 ? 147.275 154.142 106.678 1.00 50.71  ? 268 GLU B OE1   1 
ATOM   4706 O OE2   . GLU B 1 268 ? 147.873 153.028 108.474 1.00 50.71  ? 268 GLU B OE2   1 
ATOM   4707 N N     . GLU B 1 269 ? 143.557 155.920 106.006 1.00 51.68  ? 269 GLU B N     1 
ATOM   4708 C CA    . GLU B 1 269 ? 142.648 156.755 105.228 1.00 51.68  ? 269 GLU B CA    1 
ATOM   4709 C C     . GLU B 1 269 ? 141.580 155.916 104.537 1.00 51.68  ? 269 GLU B C     1 
ATOM   4710 O O     . GLU B 1 269 ? 140.390 156.254 104.576 1.00 51.68  ? 269 GLU B O     1 
ATOM   4711 C CB    . GLU B 1 269 ? 143.441 157.569 104.206 1.00 51.68  ? 269 GLU B CB    1 
ATOM   4712 C CG    . GLU B 1 269 ? 142.635 158.637 103.491 1.00 51.68  ? 269 GLU B CG    1 
ATOM   4713 C CD    . GLU B 1 269 ? 143.511 159.603 102.717 1.00 51.68  ? 269 GLU B CD    1 
ATOM   4714 O OE1   . GLU B 1 269 ? 144.747 159.428 102.734 1.00 51.68  ? 269 GLU B OE1   1 
ATOM   4715 O OE2   . GLU B 1 269 ? 142.965 160.536 102.092 1.00 51.68  ? 269 GLU B OE2   1 
ATOM   4716 N N     . ALA B 1 270 ? 141.985 154.809 103.911 1.00 53.20  ? 270 ALA B N     1 
ATOM   4717 C CA    . ALA B 1 270 ? 141.019 153.945 103.241 1.00 53.20  ? 270 ALA B CA    1 
ATOM   4718 C C     . ALA B 1 270 ? 140.054 153.317 104.237 1.00 53.20  ? 270 ALA B C     1 
ATOM   4719 O O     . ALA B 1 270 ? 138.856 153.200 103.958 1.00 53.20  ? 270 ALA B O     1 
ATOM   4720 C CB    . ALA B 1 270 ? 141.746 152.865 102.441 1.00 53.20  ? 270 ALA B CB    1 
ATOM   4721 N N     . GLU B 1 271 ? 140.557 152.904 105.403 1.00 54.67  ? 271 GLU B N     1 
ATOM   4722 C CA    . GLU B 1 271 ? 139.685 152.312 106.412 1.00 54.67  ? 271 GLU B CA    1 
ATOM   4723 C C     . GLU B 1 271 ? 138.674 153.325 106.933 1.00 54.67  ? 271 GLU B C     1 
ATOM   4724 O O     . GLU B 1 271 ? 137.501 152.993 107.138 1.00 54.67  ? 271 GLU B O     1 
ATOM   4725 C CB    . GLU B 1 271 ? 140.520 151.744 107.559 1.00 54.67  ? 271 GLU B CB    1 
ATOM   4726 C CG    . GLU B 1 271 ? 139.709 151.010 108.616 1.00 54.67  ? 271 GLU B CG    1 
ATOM   4727 C CD    . GLU B 1 271 ? 139.038 149.759 108.082 1.00 54.67  ? 271 GLU B CD    1 
ATOM   4728 O OE1   . GLU B 1 271 ? 137.954 149.873 107.472 1.00 54.67  ? 271 GLU B OE1   1 
ATOM   4729 O OE2   . GLU B 1 271 ? 139.595 148.658 108.273 1.00 54.67  ? 271 GLU B OE2   1 
ATOM   4730 N N     . VAL B 1 272 ? 139.110 154.568 107.155 1.00 47.59  ? 272 VAL B N     1 
ATOM   4731 C CA    . VAL B 1 272 ? 138.192 155.615 107.597 1.00 47.59  ? 272 VAL B CA    1 
ATOM   4732 C C     . VAL B 1 272 ? 137.137 155.881 106.531 1.00 47.59  ? 272 VAL B C     1 
ATOM   4733 O O     . VAL B 1 272 ? 135.947 156.040 106.839 1.00 47.59  ? 272 VAL B O     1 
ATOM   4734 C CB    . VAL B 1 272 ? 138.973 156.893 107.957 1.00 47.59  ? 272 VAL B CB    1 
ATOM   4735 C CG1   . VAL B 1 272 ? 138.040 158.086 108.036 1.00 47.59  ? 272 VAL B CG1   1 
ATOM   4736 C CG2   . VAL B 1 272 ? 139.708 156.707 109.270 1.00 47.59  ? 272 VAL B CG2   1 
ATOM   4737 N N     . ASN B 1 273 ? 137.554 155.938 105.263 1.00 50.79  ? 273 ASN B N     1 
ATOM   4738 C CA    . ASN B 1 273 ? 136.592 156.140 104.184 1.00 50.79  ? 273 ASN B CA    1 
ATOM   4739 C C     . ASN B 1 273 ? 135.574 155.008 104.135 1.00 50.79  ? 273 ASN B C     1 
ATOM   4740 O O     . ASN B 1 273 ? 134.375 155.252 103.967 1.00 50.79  ? 273 ASN B O     1 
ATOM   4741 C CB    . ASN B 1 273 ? 137.317 156.266 102.844 1.00 50.79  ? 273 ASN B CB    1 
ATOM   4742 C CG    . ASN B 1 273 ? 138.278 157.434 102.809 1.00 50.79  ? 273 ASN B CG    1 
ATOM   4743 O OD1   . ASN B 1 273 ? 138.275 158.281 103.700 1.00 50.79  ? 273 ASN B OD1   1 
ATOM   4744 N ND2   . ASN B 1 273 ? 139.110 157.486 101.775 1.00 50.79  ? 273 ASN B ND2   1 
ATOM   4745 N N     . VAL B 1 274 ? 136.033 153.765 104.288 1.00 54.09  ? 274 VAL B N     1 
ATOM   4746 C CA    . VAL B 1 274 ? 135.120 152.624 104.269 1.00 54.09  ? 274 VAL B CA    1 
ATOM   4747 C C     . VAL B 1 274 ? 134.147 152.695 105.439 1.00 54.09  ? 274 VAL B C     1 
ATOM   4748 O O     . VAL B 1 274 ? 132.943 152.460 105.279 1.00 54.09  ? 274 VAL B O     1 
ATOM   4749 C CB    . VAL B 1 274 ? 135.912 151.304 104.269 1.00 54.09  ? 274 VAL B CB    1 
ATOM   4750 C CG1   . VAL B 1 274 ? 134.990 150.130 104.556 1.00 54.09  ? 274 VAL B CG1   1 
ATOM   4751 C CG2   . VAL B 1 274 ? 136.615 151.111 102.936 1.00 54.09  ? 274 VAL B CG2   1 
ATOM   4752 N N     . LYS B 1 275 ? 134.649 153.019 106.633 1.00 49.26  ? 275 LYS B N     1 
ATOM   4753 C CA    . LYS B 1 275 ? 133.783 153.089 107.807 1.00 49.26  ? 275 LYS B CA    1 
ATOM   4754 C C     . LYS B 1 275 ? 132.721 154.168 107.644 1.00 49.26  ? 275 LYS B C     1 
ATOM   4755 O O     . LYS B 1 275 ? 131.543 153.948 107.947 1.00 49.26  ? 275 LYS B O     1 
ATOM   4756 C CB    . LYS B 1 275 ? 134.618 153.341 109.062 1.00 49.26  ? 275 LYS B CB    1 
ATOM   4757 C CG    . LYS B 1 275 ? 135.210 152.086 109.670 1.00 49.26  ? 275 LYS B CG    1 
ATOM   4758 C CD    . LYS B 1 275 ? 135.993 152.401 110.930 1.00 49.26  ? 275 LYS B CD    1 
ATOM   4759 C CE    . LYS B 1 275 ? 136.473 151.131 111.605 1.00 49.26  ? 275 LYS B CE    1 
ATOM   4760 N NZ    . LYS B 1 275 ? 137.354 151.423 112.767 1.00 49.26  ? 275 LYS B NZ    1 
ATOM   4761 N N     . ILE B 1 276 ? 133.119 155.346 107.156 1.00 50.94  ? 276 ILE B N     1 
ATOM   4762 C CA    . ILE B 1 276 ? 132.144 156.416 106.973 1.00 50.94  ? 276 ILE B CA    1 
ATOM   4763 C C     . ILE B 1 276 ? 131.147 156.056 105.880 1.00 50.94  ? 276 ILE B C     1 
ATOM   4764 O O     . ILE B 1 276 ? 129.946 156.320 106.016 1.00 50.94  ? 276 ILE B O     1 
ATOM   4765 C CB    . ILE B 1 276 ? 132.853 157.749 106.681 1.00 50.94  ? 276 ILE B CB    1 
ATOM   4766 C CG1   . ILE B 1 276 ? 133.640 158.206 107.907 1.00 50.94  ? 276 ILE B CG1   1 
ATOM   4767 C CG2   . ILE B 1 276 ? 131.841 158.813 106.300 1.00 50.94  ? 276 ILE B CG2   1 
ATOM   4768 C CD1   . ILE B 1 276 ? 132.769 158.590 109.079 1.00 50.94  ? 276 ILE B CD1   1 
ATOM   4769 N N     . LYS B 1 277 ? 131.611 155.442 104.788 1.00 62.10  ? 277 LYS B N     1 
ATOM   4770 C CA    . LYS B 1 277 ? 130.698 155.027 103.730 1.00 62.10  ? 277 LYS B CA    1 
ATOM   4771 C C     . LYS B 1 277 ? 129.716 153.974 104.221 1.00 62.10  ? 277 LYS B C     1 
ATOM   4772 O O     . LYS B 1 277 ? 128.584 153.907 103.734 1.00 62.10  ? 277 LYS B O     1 
ATOM   4773 C CB    . LYS B 1 277 ? 131.489 154.499 102.533 1.00 62.10  ? 277 LYS B CB    1 
ATOM   4774 C CG    . LYS B 1 277 ? 131.974 155.580 101.584 1.00 62.10  ? 277 LYS B CG    1 
ATOM   4775 C CD    . LYS B 1 277 ? 130.871 156.025 100.642 1.00 62.10  ? 277 LYS B CD    1 
ATOM   4776 C CE    . LYS B 1 277 ? 130.354 154.864 99.811  1.00 62.10  ? 277 LYS B CE    1 
ATOM   4777 N NZ    . LYS B 1 277 ? 131.440 154.212 99.033  1.00 62.10  ? 277 LYS B NZ    1 
ATOM   4778 N N     . LYS B 1 278 ? 130.125 153.143 105.175 1.00 62.74  ? 278 LYS B N     1 
ATOM   4779 C CA    . LYS B 1 278 ? 129.233 152.143 105.744 1.00 62.74  ? 278 LYS B CA    1 
ATOM   4780 C C     . LYS B 1 278 ? 128.472 152.650 106.962 1.00 62.74  ? 278 LYS B C     1 
ATOM   4781 O O     . LYS B 1 278 ? 127.677 151.898 107.535 1.00 62.74  ? 278 LYS B O     1 
ATOM   4782 C CB    . LYS B 1 278 ? 130.020 150.881 106.108 1.00 62.74  ? 278 LYS B CB    1 
ATOM   4783 C CG    . LYS B 1 278 ? 130.304 149.979 104.918 1.00 62.74  ? 278 LYS B CG    1 
ATOM   4784 C CD    . LYS B 1 278 ? 131.238 148.842 105.288 1.00 62.74  ? 278 LYS B CD    1 
ATOM   4785 C CE    . LYS B 1 278 ? 131.530 147.965 104.083 1.00 62.74  ? 278 LYS B CE    1 
ATOM   4786 N NZ    . LYS B 1 278 ? 131.955 148.773 102.907 1.00 62.74  ? 278 LYS B NZ    1 
ATOM   4787 N N     . ALA B 1 279 ? 128.696 153.896 107.369 1.00 58.45  ? 279 ALA B N     1 
ATOM   4788 C CA    . ALA B 1 279 ? 127.982 154.457 108.506 1.00 58.45  ? 279 ALA B CA    1 
ATOM   4789 C C     . ALA B 1 279 ? 126.508 154.678 108.180 1.00 58.45  ? 279 ALA B C     1 
ATOM   4790 O O     . ALA B 1 279 ? 126.128 154.915 107.031 1.00 58.45  ? 279 ALA B O     1 
ATOM   4791 C CB    . ALA B 1 279 ? 128.617 155.777 108.935 1.00 58.45  ? 279 ALA B CB    1 
ATOM   4792 N N     . TYR B 1 280 ? 125.677 154.593 109.215 1.00 63.18  ? 280 TYR B N     1 
ATOM   4793 C CA    . TYR B 1 280 ? 124.249 154.844 109.068 1.00 63.18  ? 280 TYR B CA    1 
ATOM   4794 C C     . TYR B 1 280 ? 123.994 156.322 108.808 1.00 63.18  ? 280 TYR B C     1 
ATOM   4795 O O     . TYR B 1 280 ? 124.603 157.189 109.443 1.00 63.18  ? 280 TYR B O     1 
ATOM   4796 C CB    . TYR B 1 280 ? 123.506 154.391 110.324 1.00 63.18  ? 280 TYR B CB    1 
ATOM   4797 C CG    . TYR B 1 280 ? 122.019 154.661 110.309 1.00 63.18  ? 280 TYR B CG    1 
ATOM   4798 C CD1   . TYR B 1 280 ? 121.234 154.286 109.228 1.00 63.18  ? 280 TYR B CD1   1 
ATOM   4799 C CD2   . TYR B 1 280 ? 121.399 155.287 111.382 1.00 63.18  ? 280 TYR B CD2   1 
ATOM   4800 C CE1   . TYR B 1 280 ? 119.873 154.530 109.216 1.00 63.18  ? 280 TYR B CE1   1 
ATOM   4801 C CE2   . TYR B 1 280 ? 120.042 155.537 111.378 1.00 63.18  ? 280 TYR B CE2   1 
ATOM   4802 C CZ    . TYR B 1 280 ? 119.283 155.155 110.294 1.00 63.18  ? 280 TYR B CZ    1 
ATOM   4803 O OH    . TYR B 1 280 ? 117.930 155.402 110.288 1.00 63.18  ? 280 TYR B OH    1 
ATOM   4804 N N     . CYS B 1 281 ? 123.094 156.609 107.871 1.00 66.10  ? 281 CYS B N     1 
ATOM   4805 C CA    . CYS B 1 281 ? 122.704 157.981 107.540 1.00 66.10  ? 281 CYS B CA    1 
ATOM   4806 C C     . CYS B 1 281 ? 121.329 157.962 106.894 1.00 66.10  ? 281 CYS B C     1 
ATOM   4807 O O     . CYS B 1 281 ? 121.197 157.819 105.673 1.00 66.10  ? 281 CYS B O     1 
ATOM   4808 C CB    . CYS B 1 281 ? 123.734 158.643 106.622 1.00 66.10  ? 281 CYS B CB    1 
ATOM   4809 S SG    . CYS B 1 281 ? 123.686 160.448 106.633 1.00 66.10  ? 281 CYS B SG    1 
ATOM   4810 N N     . PRO B 1 282 ? 120.274 158.099 107.689 1.00 63.98  ? 282 PRO B N     1 
ATOM   4811 C CA    . PRO B 1 282 ? 118.921 158.115 107.130 1.00 63.98  ? 282 PRO B CA    1 
ATOM   4812 C C     . PRO B 1 282 ? 118.666 159.405 106.373 1.00 63.98  ? 282 PRO B C     1 
ATOM   4813 O O     . PRO B 1 282 ? 118.983 160.497 106.866 1.00 63.98  ? 282 PRO B O     1 
ATOM   4814 C CB    . PRO B 1 282 ? 118.024 158.010 108.371 1.00 63.98  ? 282 PRO B CB    1 
ATOM   4815 C CG    . PRO B 1 282 ? 118.847 158.579 109.472 1.00 63.98  ? 282 PRO B CG    1 
ATOM   4816 C CD    . PRO B 1 282 ? 120.277 158.247 109.153 1.00 63.98  ? 282 PRO B CD    1 
ATOM   4817 N N     . PRO B 1 283 ? 118.098 159.324 105.173 1.00 65.80  ? 283 PRO B N     1 
ATOM   4818 C CA    . PRO B 1 283 ? 117.842 160.543 104.402 1.00 65.80  ? 283 PRO B CA    1 
ATOM   4819 C C     . PRO B 1 283 ? 116.693 161.345 104.990 1.00 65.80  ? 283 PRO B C     1 
ATOM   4820 O O     . PRO B 1 283 ? 115.687 160.795 105.445 1.00 65.80  ? 283 PRO B O     1 
ATOM   4821 C CB    . PRO B 1 283 ? 117.494 160.012 103.007 1.00 65.80  ? 283 PRO B CB    1 
ATOM   4822 C CG    . PRO B 1 283 ? 116.926 158.660 103.261 1.00 65.80  ? 283 PRO B CG    1 
ATOM   4823 C CD    . PRO B 1 283 ? 117.635 158.113 104.474 1.00 65.80  ? 283 PRO B CD    1 
ATOM   4824 N N     . LYS B 1 284 ? 116.867 162.669 104.984 1.00 71.50  ? 284 LYS B N     1 
ATOM   4825 C CA    . LYS B 1 284 ? 115.862 163.615 105.460 1.00 71.50  ? 284 LYS B CA    1 
ATOM   4826 C C     . LYS B 1 284 ? 115.520 163.399 106.930 1.00 71.50  ? 284 LYS B C     1 
ATOM   4827 O O     . LYS B 1 284 ? 114.477 163.862 107.402 1.00 71.50  ? 284 LYS B O     1 
ATOM   4828 C CB    . LYS B 1 284 ? 114.592 163.529 104.606 1.00 71.50  ? 284 LYS B CB    1 
ATOM   4829 C CG    . LYS B 1 284 ? 114.550 164.512 103.445 1.00 71.50  ? 284 LYS B CG    1 
ATOM   4830 C CD    . LYS B 1 284 ? 115.562 164.152 102.370 1.00 71.50  ? 284 LYS B CD    1 
ATOM   4831 C CE    . LYS B 1 284 ? 115.251 162.799 101.751 1.00 71.50  ? 284 LYS B CE    1 
ATOM   4832 N NZ    . LYS B 1 284 ? 116.302 162.377 100.784 1.00 71.50  ? 284 LYS B NZ    1 
ATOM   4833 N N     . VAL B 1 285 ? 116.386 162.702 107.661 1.00 66.95  ? 285 VAL B N     1 
ATOM   4834 C CA    . VAL B 1 285 ? 116.223 162.482 109.093 1.00 66.95  ? 285 VAL B CA    1 
ATOM   4835 C C     . VAL B 1 285 ? 117.447 163.043 109.800 1.00 66.95  ? 285 VAL B C     1 
ATOM   4836 O O     . VAL B 1 285 ? 118.581 162.674 109.474 1.00 66.95  ? 285 VAL B O     1 
ATOM   4837 C CB    . VAL B 1 285 ? 116.033 160.992 109.429 1.00 66.95  ? 285 VAL B CB    1 
ATOM   4838 C CG1   . VAL B 1 285 ? 115.716 160.819 110.905 1.00 66.95  ? 285 VAL B CG1   1 
ATOM   4839 C CG2   . VAL B 1 285 ? 114.930 160.391 108.573 1.00 66.95  ? 285 VAL B CG2   1 
ATOM   4840 N N     . VAL B 1 286 ? 117.218 163.927 110.765 1.00 70.67  ? 286 VAL B N     1 
ATOM   4841 C CA    . VAL B 1 286 ? 118.296 164.578 111.493 1.00 70.67  ? 286 VAL B CA    1 
ATOM   4842 C C     . VAL B 1 286 ? 118.433 164.034 112.910 1.00 70.67  ? 286 VAL B C     1 
ATOM   4843 O O     . VAL B 1 286 ? 119.533 164.006 113.460 1.00 70.67  ? 286 VAL B O     1 
ATOM   4844 C CB    . VAL B 1 286 ? 118.090 166.107 111.494 1.00 70.67  ? 286 VAL B CB    1 
ATOM   4845 C CG1   . VAL B 1 286 ? 117.917 166.603 110.072 1.00 70.67  ? 286 VAL B CG1   1 
ATOM   4846 C CG2   . VAL B 1 286 ? 116.881 166.488 112.334 1.00 70.67  ? 286 VAL B CG2   1 
ATOM   4847 N N     . GLU B 1 287 ? 117.331 163.597 113.514 1.00 79.13  ? 287 GLU B N     1 
ATOM   4848 C CA    . GLU B 1 287 ? 117.398 163.010 114.843 1.00 79.13  ? 287 GLU B CA    1 
ATOM   4849 C C     . GLU B 1 287 ? 117.842 161.558 114.743 1.00 79.13  ? 287 GLU B C     1 
ATOM   4850 O O     . GLU B 1 287 ? 117.213 160.750 114.053 1.00 79.13  ? 287 GLU B O     1 
ATOM   4851 C CB    . GLU B 1 287 ? 116.043 163.111 115.540 1.00 79.13  ? 287 GLU B CB    1 
ATOM   4852 C CG    . GLU B 1 287 ? 115.595 164.538 115.811 1.00 79.13  ? 287 GLU B CG    1 
ATOM   4853 C CD    . GLU B 1 287 ? 116.449 165.226 116.859 1.00 79.13  ? 287 GLU B CD    1 
ATOM   4854 O OE1   . GLU B 1 287 ? 116.214 164.997 118.064 1.00 79.13  ? 287 GLU B OE1   1 
ATOM   4855 O OE2   . GLU B 1 287 ? 117.357 165.994 116.478 1.00 79.13  ? 287 GLU B OE2   1 
ATOM   4856 N N     . GLY B 1 288 ? 118.928 161.226 115.435 1.00 66.32  ? 288 GLY B N     1 
ATOM   4857 C CA    . GLY B 1 288 ? 119.490 159.897 115.333 1.00 66.32  ? 288 GLY B CA    1 
ATOM   4858 C C     . GLY B 1 288 ? 120.308 159.650 114.090 1.00 66.32  ? 288 GLY B C     1 
ATOM   4859 O O     . GLY B 1 288 ? 120.458 158.495 113.682 1.00 66.32  ? 288 GLY B O     1 
ATOM   4860 N N     . ASN B 1 289 ? 120.841 160.702 113.466 1.00 59.37  ? 289 ASN B N     1 
ATOM   4861 C CA    . ASN B 1 289 ? 121.672 160.543 112.283 1.00 59.37  ? 289 ASN B CA    1 
ATOM   4862 C C     . ASN B 1 289 ? 123.131 160.548 112.707 1.00 59.37  ? 289 ASN B C     1 
ATOM   4863 O O     . ASN B 1 289 ? 123.652 161.609 113.092 1.00 59.37  ? 289 ASN B O     1 
ATOM   4864 C CB    . ASN B 1 289 ? 121.406 161.660 111.277 1.00 59.37  ? 289 ASN B CB    1 
ATOM   4865 C CG    . ASN B 1 289 ? 122.091 161.421 109.945 1.00 59.37  ? 289 ASN B CG    1 
ATOM   4866 O OD1   . ASN B 1 289 ? 122.808 160.438 109.768 1.00 59.37  ? 289 ASN B OD1   1 
ATOM   4867 N ND2   . ASN B 1 289 ? 121.868 162.322 108.996 1.00 59.37  ? 289 ASN B ND2   1 
ATOM   4868 N N     . PRO B 1 290 ? 123.821 159.403 112.672 1.00 52.60  ? 290 PRO B N     1 
ATOM   4869 C CA    . PRO B 1 290 ? 125.228 159.391 113.096 1.00 52.60  ? 290 PRO B CA    1 
ATOM   4870 C C     . PRO B 1 290 ? 126.103 160.330 112.293 1.00 52.60  ? 290 PRO B C     1 
ATOM   4871 O O     . PRO B 1 290 ? 126.951 161.010 112.873 1.00 52.60  ? 290 PRO B O     1 
ATOM   4872 C CB    . PRO B 1 290 ? 125.637 157.926 112.899 1.00 52.60  ? 290 PRO B CB    1 
ATOM   4873 C CG    . PRO B 1 290 ? 124.363 157.166 112.971 1.00 52.60  ? 290 PRO B CG    1 
ATOM   4874 C CD    . PRO B 1 290 ? 123.328 158.055 112.353 1.00 52.60  ? 290 PRO B CD    1 
ATOM   4875 N N     . CYS B 1 291 ? 125.904 160.415 110.977 1.00 55.62  ? 291 CYS B N     1 
ATOM   4876 C CA    . CYS B 1 291 ? 126.740 161.296 110.167 1.00 55.62  ? 291 CYS B CA    1 
ATOM   4877 C C     . CYS B 1 291 ? 126.499 162.760 110.508 1.00 55.62  ? 291 CYS B C     1 
ATOM   4878 O O     . CYS B 1 291 ? 127.453 163.534 110.651 1.00 55.62  ? 291 CYS B O     1 
ATOM   4879 C CB    . CYS B 1 291 ? 126.489 161.044 108.683 1.00 55.62  ? 291 CYS B CB    1 
ATOM   4880 S SG    . CYS B 1 291 ? 126.896 159.375 108.147 1.00 55.62  ? 291 CYS B SG    1 
ATOM   4881 N N     . LEU B 1 292 ? 125.233 163.161 110.641 1.00 56.06  ? 292 LEU B N     1 
ATOM   4882 C CA    . LEU B 1 292 ? 124.939 164.550 110.976 1.00 56.06  ? 292 LEU B CA    1 
ATOM   4883 C C     . LEU B 1 292 ? 125.482 164.914 112.349 1.00 56.06  ? 292 LEU B C     1 
ATOM   4884 O O     . LEU B 1 292 ? 126.027 166.006 112.536 1.00 56.06  ? 292 LEU B O     1 
ATOM   4885 C CB    . LEU B 1 292 ? 123.435 164.805 110.915 1.00 56.06  ? 292 LEU B CB    1 
ATOM   4886 C CG    . LEU B 1 292 ? 122.929 165.487 109.647 1.00 56.06  ? 292 LEU B CG    1 
ATOM   4887 C CD1   . LEU B 1 292 ? 121.419 165.558 109.671 1.00 56.06  ? 292 LEU B CD1   1 
ATOM   4888 C CD2   . LEU B 1 292 ? 123.531 166.874 109.511 1.00 56.06  ? 292 LEU B CD2   1 
ATOM   4889 N N     . GLU B 1 293 ? 125.337 164.017 113.326 1.00 50.69  ? 293 GLU B N     1 
ATOM   4890 C CA    . GLU B 1 293 ? 125.859 164.302 114.658 1.00 50.69  ? 293 GLU B CA    1 
ATOM   4891 C C     . GLU B 1 293 ? 127.385 164.344 114.652 1.00 50.69  ? 293 GLU B C     1 
ATOM   4892 O O     . GLU B 1 293 ? 127.996 165.197 115.315 1.00 50.69  ? 293 GLU B O     1 
ATOM   4893 C CB    . GLU B 1 293 ? 125.310 163.269 115.643 1.00 50.69  ? 293 GLU B CB    1 
ATOM   4894 C CG    . GLU B 1 293 ? 126.107 163.051 116.905 1.00 50.69  ? 293 GLU B CG    1 
ATOM   4895 C CD    . GLU B 1 293 ? 126.388 164.320 117.672 1.00 50.69  ? 293 GLU B CD    1 
ATOM   4896 O OE1   . GLU B 1 293 ? 127.580 164.612 117.890 1.00 50.69  ? 293 GLU B OE1   1 
ATOM   4897 O OE2   . GLU B 1 293 ? 125.429 165.033 118.034 1.00 50.69  ? 293 GLU B OE2   1 
ATOM   4898 N N     . TYR B 1 294 ? 128.017 163.442 113.894 1.00 42.07  ? 294 TYR B N     1 
ATOM   4899 C CA    . TYR B 1 294 ? 129.459 163.504 113.689 1.00 42.07  ? 294 TYR B CA    1 
ATOM   4900 C C     . TYR B 1 294 ? 129.867 164.869 113.160 1.00 42.07  ? 294 TYR B C     1 
ATOM   4901 O O     . TYR B 1 294 ? 130.788 165.500 113.687 1.00 42.07  ? 294 TYR B O     1 
ATOM   4902 C CB    . TYR B 1 294 ? 129.898 162.408 112.716 1.00 42.07  ? 294 TYR B CB    1 
ATOM   4903 C CG    . TYR B 1 294 ? 130.432 161.146 113.357 1.00 42.07  ? 294 TYR B CG    1 
ATOM   4904 C CD1   . TYR B 1 294 ? 129.581 160.242 113.974 1.00 42.07  ? 294 TYR B CD1   1 
ATOM   4905 C CD2   . TYR B 1 294 ? 131.783 160.845 113.319 1.00 42.07  ? 294 TYR B CD2   1 
ATOM   4906 C CE1   . TYR B 1 294 ? 130.061 159.087 114.548 1.00 42.07  ? 294 TYR B CE1   1 
ATOM   4907 C CE2   . TYR B 1 294 ? 132.273 159.693 113.893 1.00 42.07  ? 294 TYR B CE2   1 
ATOM   4908 C CZ    . TYR B 1 294 ? 131.408 158.816 114.506 1.00 42.07  ? 294 TYR B CZ    1 
ATOM   4909 O OH    . TYR B 1 294 ? 131.888 157.664 115.082 1.00 42.07  ? 294 TYR B OH    1 
ATOM   4910 N N     . ILE B 1 295 ? 129.176 165.350 112.126 1.00 39.31  ? 295 ILE B N     1 
ATOM   4911 C CA    . ILE B 1 295 ? 129.487 166.671 111.586 1.00 39.31  ? 295 ILE B CA    1 
ATOM   4912 C C     . ILE B 1 295 ? 129.338 167.725 112.671 1.00 39.31  ? 295 ILE B C     1 
ATOM   4913 O O     . ILE B 1 295 ? 130.285 168.458 112.974 1.00 39.31  ? 295 ILE B O     1 
ATOM   4914 C CB    . ILE B 1 295 ? 128.596 166.989 110.373 1.00 39.31  ? 295 ILE B CB    1 
ATOM   4915 C CG1   . ILE B 1 295 ? 128.859 166.005 109.238 1.00 39.31  ? 295 ILE B CG1   1 
ATOM   4916 C CG2   . ILE B 1 295 ? 128.849 168.404 109.897 1.00 39.31  ? 295 ILE B CG2   1 
ATOM   4917 C CD1   . ILE B 1 295 ? 127.655 165.770 108.365 1.00 39.31  ? 295 ILE B CD1   1 
ATOM   4918 N N     . LYS B 1 296 ? 128.189 167.719 113.353 1.00 41.85  ? 296 LYS B N     1 
ATOM   4919 C CA    . LYS B 1 296 ? 127.844 168.783 114.288 1.00 41.85  ? 296 LYS B CA    1 
ATOM   4920 C C     . LYS B 1 296 ? 128.869 168.913 115.404 1.00 41.85  ? 296 LYS B C     1 
ATOM   4921 O O     . LYS B 1 296 ? 129.272 170.027 115.755 1.00 41.85  ? 296 LYS B O     1 
ATOM   4922 C CB    . LYS B 1 296 ? 126.460 168.520 114.880 1.00 41.85  ? 296 LYS B CB    1 
ATOM   4923 C CG    . LYS B 1 296 ? 126.080 169.461 116.006 1.00 41.85  ? 296 LYS B CG    1 
ATOM   4924 C CD    . LYS B 1 296 ? 124.869 168.949 116.765 1.00 41.85  ? 296 LYS B CD    1 
ATOM   4925 C CE    . LYS B 1 296 ? 124.603 169.787 118.002 1.00 41.85  ? 296 LYS B CE    1 
ATOM   4926 N NZ    . LYS B 1 296 ? 123.430 169.288 118.768 1.00 41.85  ? 296 LYS B NZ    1 
ATOM   4927 N N     . TYR B 1 297 ? 129.302 167.793 115.981 1.00 40.53  ? 297 TYR B N     1 
ATOM   4928 C CA    . TYR B 1 297 ? 130.194 167.894 117.130 1.00 40.53  ? 297 TYR B CA    1 
ATOM   4929 C C     . TYR B 1 297 ? 131.655 167.588 116.826 1.00 40.53  ? 297 TYR B C     1 
ATOM   4930 O O     . TYR B 1 297 ? 132.475 167.631 117.750 1.00 40.53  ? 297 TYR B O     1 
ATOM   4931 C CB    . TYR B 1 297 ? 129.707 166.995 118.271 1.00 40.53  ? 297 TYR B CB    1 
ATOM   4932 C CG    . TYR B 1 297 ? 128.695 167.677 119.168 1.00 40.53  ? 297 TYR B CG    1 
ATOM   4933 C CD1   . TYR B 1 297 ? 127.494 167.064 119.498 1.00 40.53  ? 297 TYR B CD1   1 
ATOM   4934 C CD2   . TYR B 1 297 ? 128.948 168.938 119.690 1.00 40.53  ? 297 TYR B CD2   1 
ATOM   4935 C CE1   . TYR B 1 297 ? 126.574 167.687 120.317 1.00 40.53  ? 297 TYR B CE1   1 
ATOM   4936 C CE2   . TYR B 1 297 ? 128.035 169.570 120.509 1.00 40.53  ? 297 TYR B CE2   1 
ATOM   4937 C CZ    . TYR B 1 297 ? 126.850 168.941 120.820 1.00 40.53  ? 297 TYR B CZ    1 
ATOM   4938 O OH    . TYR B 1 297 ? 125.938 169.568 121.636 1.00 40.53  ? 297 TYR B OH    1 
ATOM   4939 N N     . LEU B 1 298 ? 132.019 167.302 115.574 1.00 34.40  ? 298 LEU B N     1 
ATOM   4940 C CA    . LEU B 1 298 ? 133.423 167.103 115.231 1.00 34.40  ? 298 LEU B CA    1 
ATOM   4941 C C     . LEU B 1 298 ? 133.894 168.081 114.165 1.00 34.40  ? 298 LEU B C     1 
ATOM   4942 O O     . LEU B 1 298 ? 134.916 168.748 114.353 1.00 34.40  ? 298 LEU B O     1 
ATOM   4943 C CB    . LEU B 1 298 ? 133.653 165.662 114.755 1.00 34.40  ? 298 LEU B CB    1 
ATOM   4944 C CG    . LEU B 1 298 ? 133.067 164.518 115.582 1.00 34.40  ? 298 LEU B CG    1 
ATOM   4945 C CD1   . LEU B 1 298 ? 133.556 163.184 115.057 1.00 34.40  ? 298 LEU B CD1   1 
ATOM   4946 C CD2   . LEU B 1 298 ? 133.376 164.668 117.045 1.00 34.40  ? 298 LEU B CD2   1 
ATOM   4947 N N     . ILE B 1 299 ? 133.175 168.185 113.045 1.00 33.60  ? 299 ILE B N     1 
ATOM   4948 C CA    . ILE B 1 299 ? 133.711 168.873 111.878 1.00 33.60  ? 299 ILE B CA    1 
ATOM   4949 C C     . ILE B 1 299 ? 133.496 170.373 112.003 1.00 33.60  ? 299 ILE B C     1 
ATOM   4950 O O     . ILE B 1 299 ? 134.436 171.166 111.868 1.00 33.60  ? 299 ILE B O     1 
ATOM   4951 C CB    . ILE B 1 299 ? 133.058 168.318 110.600 1.00 33.60  ? 299 ILE B CB    1 
ATOM   4952 C CG1   . ILE B 1 299 ? 133.318 166.817 110.483 1.00 33.60  ? 299 ILE B CG1   1 
ATOM   4953 C CG2   . ILE B 1 299 ? 133.574 169.053 109.381 1.00 33.60  ? 299 ILE B CG2   1 
ATOM   4954 C CD1   . ILE B 1 299 ? 134.772 166.457 110.395 1.00 33.60  ? 299 ILE B CD1   1 
ATOM   4955 N N     . LEU B 1 300 ? 132.259 170.782 112.258 1.00 41.15  ? 300 LEU B N     1 
ATOM   4956 C CA    . LEU B 1 300 ? 131.900 172.186 112.401 1.00 41.15  ? 300 LEU B CA    1 
ATOM   4957 C C     . LEU B 1 300 ? 132.677 172.871 113.525 1.00 41.15  ? 300 LEU B C     1 
ATOM   4958 O O     . LEU B 1 300 ? 133.215 173.961 113.302 1.00 41.15  ? 300 LEU B O     1 
ATOM   4959 C CB    . LEU B 1 300 ? 130.392 172.325 112.625 1.00 41.15  ? 300 LEU B CB    1 
ATOM   4960 C CG    . LEU B 1 300 ? 129.525 172.012 111.404 1.00 41.15  ? 300 LEU B CG    1 
ATOM   4961 C CD1   . LEU B 1 300 ? 128.049 172.037 111.767 1.00 41.15  ? 300 LEU B CD1   1 
ATOM   4962 C CD2   . LEU B 1 300 ? 129.822 172.988 110.279 1.00 41.15  ? 300 LEU B CD2   1 
ATOM   4963 N N     . PRO B 1 301 ? 132.781 172.292 114.730 1.00 37.70  ? 301 PRO B N     1 
ATOM   4964 C CA    . PRO B 1 301 ? 133.525 172.995 115.789 1.00 37.70  ? 301 PRO B CA    1 
ATOM   4965 C C     . PRO B 1 301 ? 135.003 173.168 115.487 1.00 37.70  ? 301 PRO B C     1 
ATOM   4966 O O     . PRO B 1 301 ? 135.658 174.007 116.118 1.00 37.70  ? 301 PRO B O     1 
ATOM   4967 C CB    . PRO B 1 301 ? 133.302 172.111 117.024 1.00 37.70  ? 301 PRO B CB    1 
ATOM   4968 C CG    . PRO B 1 301 ? 132.972 170.781 116.484 1.00 37.70  ? 301 PRO B CG    1 
ATOM   4969 C CD    . PRO B 1 301 ? 132.203 171.033 115.233 1.00 37.70  ? 301 PRO B CD    1 
ATOM   4970 N N     . TRP B 1 302 ? 135.556 172.402 114.544 1.00 32.84  ? 302 TRP B N     1 
ATOM   4971 C CA    . TRP B 1 302 ? 136.979 172.528 114.247 1.00 32.84  ? 302 TRP B CA    1 
ATOM   4972 C C     . TRP B 1 302 ? 137.239 173.617 113.212 1.00 32.84  ? 302 TRP B C     1 
ATOM   4973 O O     . TRP B 1 302 ? 137.988 174.565 113.476 1.00 32.84  ? 302 TRP B O     1 
ATOM   4974 C CB    . TRP B 1 302 ? 137.541 171.191 113.766 1.00 32.84  ? 302 TRP B CB    1 
ATOM   4975 C CG    . TRP B 1 302 ? 139.026 171.094 113.917 1.00 32.84  ? 302 TRP B CG    1 
ATOM   4976 C CD1   . TRP B 1 302 ? 139.967 171.811 113.241 1.00 32.84  ? 302 TRP B CD1   1 
ATOM   4977 C CD2   . TRP B 1 302 ? 139.743 170.227 114.802 1.00 32.84  ? 302 TRP B CD2   1 
ATOM   4978 N NE1   . TRP B 1 302 ? 141.226 171.447 113.650 1.00 32.84  ? 302 TRP B NE1   1 
ATOM   4979 C CE2   . TRP B 1 302 ? 141.115 170.475 114.609 1.00 32.84  ? 302 TRP B CE2   1 
ATOM   4980 C CE3   . TRP B 1 302 ? 139.359 169.266 115.740 1.00 32.84  ? 302 TRP B CE3   1 
ATOM   4981 C CZ2   . TRP B 1 302 ? 142.102 169.799 115.317 1.00 32.84  ? 302 TRP B CZ2   1 
ATOM   4982 C CZ3   . TRP B 1 302 ? 140.340 168.598 116.442 1.00 32.84  ? 302 TRP B CZ3   1 
ATOM   4983 C CH2   . TRP B 1 302 ? 141.694 168.865 116.227 1.00 32.84  ? 302 TRP B CH2   1 
ATOM   4984 N N     . PHE B 1 303 ? 136.635 173.500 112.029 1.00 40.52  ? 303 PHE B N     1 
ATOM   4985 C CA    . PHE B 1 303 ? 136.893 174.421 110.931 1.00 40.52  ? 303 PHE B CA    1 
ATOM   4986 C C     . PHE B 1 303 ? 135.908 175.578 110.841 1.00 40.52  ? 303 PHE B C     1 
ATOM   4987 O O     . PHE B 1 303 ? 136.043 176.406 109.932 1.00 40.52  ? 303 PHE B O     1 
ATOM   4988 C CB    . PHE B 1 303 ? 136.891 173.668 109.592 1.00 40.52  ? 303 PHE B CB    1 
ATOM   4989 C CG    . PHE B 1 303 ? 137.787 172.465 109.566 1.00 40.52  ? 303 PHE B CG    1 
ATOM   4990 C CD1   . PHE B 1 303 ? 139.083 172.539 110.044 1.00 40.52  ? 303 PHE B CD1   1 
ATOM   4991 C CD2   . PHE B 1 303 ? 137.333 171.258 109.061 1.00 40.52  ? 303 PHE B CD2   1 
ATOM   4992 C CE1   . PHE B 1 303 ? 139.910 171.434 110.014 1.00 40.52  ? 303 PHE B CE1   1 
ATOM   4993 C CE2   . PHE B 1 303 ? 138.156 170.151 109.033 1.00 40.52  ? 303 PHE B CE2   1 
ATOM   4994 C CZ    . PHE B 1 303 ? 139.444 170.238 109.510 1.00 40.52  ? 303 PHE B CZ    1 
ATOM   4995 N N     . ASN B 1 304 ? 134.928 175.665 111.744 1.00 50.42  ? 304 ASN B N     1 
ATOM   4996 C CA    . ASN B 1 304 ? 133.885 176.691 111.692 1.00 50.42  ? 304 ASN B CA    1 
ATOM   4997 C C     . ASN B 1 304 ? 133.126 176.662 110.367 1.00 50.42  ? 304 ASN B C     1 
ATOM   4998 O O     . ASN B 1 304 ? 132.524 177.660 109.964 1.00 50.42  ? 304 ASN B O     1 
ATOM   4999 C CB    . ASN B 1 304 ? 134.461 178.086 111.951 1.00 50.42  ? 304 ASN B CB    1 
ATOM   5000 C CG    . ASN B 1 304 ? 135.063 178.219 113.335 1.00 50.42  ? 304 ASN B CG    1 
ATOM   5001 O OD1   . ASN B 1 304 ? 134.714 177.474 114.250 1.00 50.42  ? 304 ASN B OD1   1 
ATOM   5002 N ND2   . ASN B 1 304 ? 135.973 179.172 113.495 1.00 50.42  ? 304 ASN B ND2   1 
ATOM   5003 N N     . GLU B 1 305 ? 133.144 175.517 109.688 1.00 48.20  ? 305 GLU B N     1 
ATOM   5004 C CA    . GLU B 1 305 ? 132.519 175.370 108.380 1.00 48.20  ? 305 GLU B CA    1 
ATOM   5005 C C     . GLU B 1 305 ? 132.483 173.893 108.022 1.00 48.20  ? 305 GLU B C     1 
ATOM   5006 O O     . GLU B 1 305 ? 133.134 173.065 108.664 1.00 48.20  ? 305 GLU B O     1 
ATOM   5007 C CB    . GLU B 1 305 ? 133.269 176.158 107.301 1.00 48.20  ? 305 GLU B CB    1 
ATOM   5008 C CG    . GLU B 1 305 ? 134.668 175.634 107.023 1.00 48.20  ? 305 GLU B CG    1 
ATOM   5009 C CD    . GLU B 1 305 ? 135.425 176.491 106.030 1.00 48.20  ? 305 GLU B CD    1 
ATOM   5010 O OE1   . GLU B 1 305 ? 134.841 177.470 105.522 1.00 48.20  ? 305 GLU B OE1   1 
ATOM   5011 O OE2   . GLU B 1 305 ? 136.605 176.185 105.759 1.00 48.20  ? 305 GLU B OE2   1 
ATOM   5012 N N     . PHE B 1 306 ? 131.707 173.575 106.985 1.00 53.15  ? 306 PHE B N     1 
ATOM   5013 C CA    . PHE B 1 306 ? 131.647 172.230 106.416 1.00 53.15  ? 306 PHE B CA    1 
ATOM   5014 C C     . PHE B 1 306 ? 131.514 172.357 104.896 1.00 53.15  ? 306 PHE B C     1 
ATOM   5015 O O     . PHE B 1 306 ? 130.413 172.476 104.357 1.00 53.15  ? 306 PHE B O     1 
ATOM   5016 C CB    . PHE B 1 306 ? 130.498 171.425 107.016 1.00 53.15  ? 306 PHE B CB    1 
ATOM   5017 C CG    . PHE B 1 306 ? 130.343 170.059 106.419 1.00 53.15  ? 306 PHE B CG    1 
ATOM   5018 C CD1   . PHE B 1 306 ? 131.297 169.082 106.637 1.00 53.15  ? 306 PHE B CD1   1 
ATOM   5019 C CD2   . PHE B 1 306 ? 129.243 169.752 105.639 1.00 53.15  ? 306 PHE B CD2   1 
ATOM   5020 C CE1   . PHE B 1 306 ? 131.157 167.825 106.087 1.00 53.15  ? 306 PHE B CE1   1 
ATOM   5021 C CE2   . PHE B 1 306 ? 129.098 168.496 105.088 1.00 53.15  ? 306 PHE B CE2   1 
ATOM   5022 C CZ    . PHE B 1 306 ? 130.056 167.532 105.312 1.00 53.15  ? 306 PHE B CZ    1 
ATOM   5023 N N     . THR B 1 307 ? 132.650 172.326 104.206 1.00 59.37  ? 307 THR B N     1 
ATOM   5024 C CA    . THR B 1 307 ? 132.649 172.473 102.757 1.00 59.37  ? 307 THR B CA    1 
ATOM   5025 C C     . THR B 1 307 ? 132.335 171.142 102.090 1.00 59.37  ? 307 THR B C     1 
ATOM   5026 O O     . THR B 1 307 ? 132.977 170.127 102.374 1.00 59.37  ? 307 THR B O     1 
ATOM   5027 C CB    . THR B 1 307 ? 134.003 172.998 102.281 1.00 59.37  ? 307 THR B CB    1 
ATOM   5028 O OG1   . THR B 1 307 ? 134.240 174.294 102.845 1.00 59.37  ? 307 THR B OG1   1 
ATOM   5029 C CG2   . THR B 1 307 ? 134.031 173.098 100.764 1.00 59.37  ? 307 THR B CG2   1 
ATOM   5030 N N     . VAL B 1 308 ? 131.346 171.149 101.200 1.00 63.64  ? 308 VAL B N     1 
ATOM   5031 C CA    . VAL B 1 308 ? 130.955 169.971 100.436 1.00 63.64  ? 308 VAL B CA    1 
ATOM   5032 C C     . VAL B 1 308 ? 131.033 170.310 98.953  1.00 63.64  ? 308 VAL B C     1 
ATOM   5033 O O     . VAL B 1 308 ? 130.579 171.378 98.527  1.00 63.64  ? 308 VAL B O     1 
ATOM   5034 C CB    . VAL B 1 308 ? 129.550 169.473 100.833 1.00 63.64  ? 308 VAL B CB    1 
ATOM   5035 C CG1   . VAL B 1 308 ? 128.478 170.494 100.487 1.00 63.64  ? 308 VAL B CG1   1 
ATOM   5036 C CG2   . VAL B 1 308 ? 129.250 168.150 100.153 1.00 63.64  ? 308 VAL B CG2   1 
ATOM   5037 N N     . GLU B 1 309 ? 131.649 169.423 98.177  1.00 77.05  ? 309 GLU B N     1 
ATOM   5038 C CA    . GLU B 1 309 ? 131.740 169.578 96.731  1.00 77.05  ? 309 GLU B CA    1 
ATOM   5039 C C     . GLU B 1 309 ? 130.769 168.606 96.072  1.00 77.05  ? 309 GLU B C     1 
ATOM   5040 O O     . GLU B 1 309 ? 130.823 167.398 96.324  1.00 77.05  ? 309 GLU B O     1 
ATOM   5041 C CB    . GLU B 1 309 ? 133.168 169.346 96.238  1.00 77.05  ? 309 GLU B CB    1 
ATOM   5042 C CG    . GLU B 1 309 ? 133.842 168.104 96.788  1.00 77.05  ? 309 GLU B CG    1 
ATOM   5043 C CD    . GLU B 1 309 ? 135.350 168.232 96.810  1.00 77.05  ? 309 GLU B CD    1 
ATOM   5044 O OE1   . GLU B 1 309 ? 135.867 169.267 96.338  1.00 77.05  ? 309 GLU B OE1   1 
ATOM   5045 O OE2   . GLU B 1 309 ? 136.020 167.296 97.291  1.00 77.05  ? 309 GLU B OE2   1 
ATOM   5046 N N     . ARG B 1 310 ? 129.880 169.138 95.237  1.00 76.81  ? 310 ARG B N     1 
ATOM   5047 C CA    . ARG B 1 310 ? 128.836 168.353 94.601  1.00 76.81  ? 310 ARG B CA    1 
ATOM   5048 C C     . ARG B 1 310 ? 128.833 168.625 93.103  1.00 76.81  ? 310 ARG B C     1 
ATOM   5049 O O     . ARG B 1 310 ? 129.432 169.590 92.623  1.00 76.81  ? 310 ARG B O     1 
ATOM   5050 C CB    . ARG B 1 310 ? 127.455 168.668 95.199  1.00 76.81  ? 310 ARG B CB    1 
ATOM   5051 C CG    . ARG B 1 310 ? 127.476 168.918 96.700  1.00 76.81  ? 310 ARG B CG    1 
ATOM   5052 C CD    . ARG B 1 310 ? 126.078 169.061 97.277  1.00 76.81  ? 310 ARG B CD    1 
ATOM   5053 N NE    . ARG B 1 310 ? 125.403 170.261 96.798  1.00 76.81  ? 310 ARG B NE    1 
ATOM   5054 C CZ    . ARG B 1 310 ? 124.318 170.781 97.355  1.00 76.81  ? 310 ARG B CZ    1 
ATOM   5055 N NH1   . ARG B 1 310 ? 123.757 170.231 98.418  1.00 76.81  ? 310 ARG B NH1   1 
ATOM   5056 N NH2   . ARG B 1 310 ? 123.783 171.880 96.831  1.00 76.81  ? 310 ARG B NH2   1 
ATOM   5057 N N     . SER B 1 311 ? 128.154 167.750 92.367  1.00 87.38  ? 311 SER B N     1 
ATOM   5058 C CA    . SER B 1 311 ? 128.039 167.916 90.928  1.00 87.38  ? 311 SER B CA    1 
ATOM   5059 C C     . SER B 1 311 ? 127.159 169.119 90.599  1.00 87.38  ? 311 SER B C     1 
ATOM   5060 O O     . SER B 1 311 ? 126.372 169.594 91.423  1.00 87.38  ? 311 SER B O     1 
ATOM   5061 C CB    . SER B 1 311 ? 127.466 166.653 90.285  1.00 87.38  ? 311 SER B CB    1 
ATOM   5062 O OG    . SER B 1 311 ? 126.234 166.289 90.884  1.00 87.38  ? 311 SER B OG    1 
ATOM   5063 N N     . ALA B 1 312 ? 127.308 169.616 89.368  1.00 88.23  ? 312 ALA B N     1 
ATOM   5064 C CA    . ALA B 1 312 ? 126.524 170.767 88.934  1.00 88.23  ? 312 ALA B CA    1 
ATOM   5065 C C     . ALA B 1 312 ? 125.030 170.475 88.971  1.00 88.23  ? 312 ALA B C     1 
ATOM   5066 O O     . ALA B 1 312 ? 124.229 171.372 89.257  1.00 88.23  ? 312 ALA B O     1 
ATOM   5067 C CB    . ALA B 1 312 ? 126.947 171.194 87.529  1.00 88.23  ? 312 ALA B CB    1 
ATOM   5068 N N     . ASP B 1 313 ? 124.636 169.232 88.686  1.00 90.01  ? 313 ASP B N     1 
ATOM   5069 C CA    . ASP B 1 313 ? 123.229 168.864 88.793  1.00 90.01  ? 313 ASP B CA    1 
ATOM   5070 C C     . ASP B 1 313 ? 122.781 168.777 90.246  1.00 90.01  ? 313 ASP B C     1 
ATOM   5071 O O     . ASP B 1 313 ? 121.584 168.891 90.532  1.00 90.01  ? 313 ASP B O     1 
ATOM   5072 C CB    . ASP B 1 313 ? 122.978 167.535 88.081  1.00 90.01  ? 313 ASP B CB    1 
ATOM   5073 C CG    . ASP B 1 313 ? 123.224 167.619 86.589  1.00 90.01  ? 313 ASP B CG    1 
ATOM   5074 O OD1   . ASP B 1 313 ? 123.034 168.712 86.015  1.00 90.01  ? 313 ASP B OD1   1 
ATOM   5075 O OD2   . ASP B 1 313 ? 123.608 166.593 85.989  1.00 90.01  ? 313 ASP B OD2   1 
ATOM   5076 N N     . ASN B 1 314 ? 123.719 168.576 91.173  1.00 88.01  ? 314 ASN B N     1 
ATOM   5077 C CA    . ASN B 1 314 ? 123.415 168.456 92.593  1.00 88.01  ? 314 ASN B CA    1 
ATOM   5078 C C     . ASN B 1 314 ? 123.763 169.720 93.372  1.00 88.01  ? 314 ASN B C     1 
ATOM   5079 O O     . ASN B 1 314 ? 124.158 169.641 94.540  1.00 88.01  ? 314 ASN B O     1 
ATOM   5080 C CB    . ASN B 1 314 ? 124.140 167.249 93.189  1.00 88.01  ? 314 ASN B CB    1 
ATOM   5081 C CG    . ASN B 1 314 ? 123.467 165.937 92.844  1.00 88.01  ? 314 ASN B CG    1 
ATOM   5082 O OD1   . ASN B 1 314 ? 122.391 165.916 92.245  1.00 88.01  ? 314 ASN B OD1   1 
ATOM   5083 N ND2   . ASN B 1 314 ? 124.097 164.830 93.221  1.00 88.01  ? 314 ASN B ND2   1 
ATOM   5084 N N     . GLY B 1 315 ? 123.629 170.889 92.746  1.00 82.24  ? 315 GLY B N     1 
ATOM   5085 C CA    . GLY B 1 315 ? 123.870 172.151 93.409  1.00 82.24  ? 315 GLY B CA    1 
ATOM   5086 C C     . GLY B 1 315 ? 125.296 172.654 93.349  1.00 82.24  ? 315 GLY B C     1 
ATOM   5087 O O     . GLY B 1 315 ? 125.549 173.792 93.763  1.00 82.24  ? 315 GLY B O     1 
ATOM   5088 N N     . GLY B 1 316 ? 126.232 171.851 92.851  1.00 82.06  ? 316 GLY B N     1 
ATOM   5089 C CA    . GLY B 1 316 ? 127.601 172.308 92.731  1.00 82.06  ? 316 GLY B CA    1 
ATOM   5090 C C     . GLY B 1 316 ? 128.298 172.438 94.078  1.00 82.06  ? 316 GLY B C     1 
ATOM   5091 O O     . GLY B 1 316 ? 127.840 171.940 95.110  1.00 82.06  ? 316 GLY B O     1 
ATOM   5092 N N     . ASN B 1 317 ? 129.433 173.132 94.048  1.00 78.46  ? 317 ASN B N     1 
ATOM   5093 C CA    . ASN B 1 317 ? 130.212 173.350 95.259  1.00 78.46  ? 317 ASN B CA    1 
ATOM   5094 C C     . ASN B 1 317 ? 129.501 174.345 96.167  1.00 78.46  ? 317 ASN B C     1 
ATOM   5095 O O     . ASN B 1 317 ? 129.099 175.426 95.726  1.00 78.46  ? 317 ASN B O     1 
ATOM   5096 C CB    . ASN B 1 317 ? 131.607 173.862 94.905  1.00 78.46  ? 317 ASN B CB    1 
ATOM   5097 C CG    . ASN B 1 317 ? 132.382 172.889 94.040  1.00 78.46  ? 317 ASN B CG    1 
ATOM   5098 O OD1   . ASN B 1 317 ? 132.257 171.674 94.186  1.00 78.46  ? 317 ASN B OD1   1 
ATOM   5099 N ND2   . ASN B 1 317 ? 133.190 173.421 93.130  1.00 78.46  ? 317 ASN B ND2   1 
ATOM   5100 N N     . LYS B 1 318 ? 129.345 173.979 97.436  1.00 72.01  ? 318 LYS B N     1 
ATOM   5101 C CA    . LYS B 1 318 ? 128.683 174.836 98.408  1.00 72.01  ? 318 LYS B CA    1 
ATOM   5102 C C     . LYS B 1 318 ? 129.322 174.630 99.772  1.00 72.01  ? 318 LYS B C     1 
ATOM   5103 O O     . LYS B 1 318 ? 129.714 173.513 100.119 1.00 72.01  ? 318 LYS B O     1 
ATOM   5104 C CB    . LYS B 1 318 ? 127.178 174.546 98.468  1.00 72.01  ? 318 LYS B CB    1 
ATOM   5105 C CG    . LYS B 1 318 ? 126.363 175.614 99.176  1.00 72.01  ? 318 LYS B CG    1 
ATOM   5106 C CD    . LYS B 1 318 ? 124.874 175.325 99.073  1.00 72.01  ? 318 LYS B CD    1 
ATOM   5107 C CE    . LYS B 1 318 ? 124.056 176.603 99.146  1.00 72.01  ? 318 LYS B CE    1 
ATOM   5108 N NZ    . LYS B 1 318 ? 124.530 177.621 98.168  1.00 72.01  ? 318 LYS B NZ    1 
ATOM   5109 N N     . THR B 1 319 ? 129.424 175.710 100.541 1.00 66.34  ? 319 THR B N     1 
ATOM   5110 C CA    . THR B 1 319 ? 130.051 175.686 101.855 1.00 66.34  ? 319 THR B CA    1 
ATOM   5111 C C     . THR B 1 319 ? 129.012 176.020 102.914 1.00 66.34  ? 319 THR B C     1 
ATOM   5112 O O     . THR B 1 319 ? 128.295 177.019 102.792 1.00 66.34  ? 319 THR B O     1 
ATOM   5113 C CB    . THR B 1 319 ? 131.218 176.673 101.930 1.00 66.34  ? 319 THR B CB    1 
ATOM   5114 O OG1   . THR B 1 319 ? 132.164 176.376 100.895 1.00 66.34  ? 319 THR B OG1   1 
ATOM   5115 C CG2   . THR B 1 319 ? 131.909 176.580 103.282 1.00 66.34  ? 319 THR B CG2   1 
ATOM   5116 N N     . PHE B 1 320 ? 128.934 175.186 103.947 1.00 64.83  ? 320 PHE B N     1 
ATOM   5117 C CA    . PHE B 1 320 ? 127.977 175.359 105.034 1.00 64.83  ? 320 PHE B CA    1 
ATOM   5118 C C     . PHE B 1 320 ? 128.718 175.881 106.258 1.00 64.83  ? 320 PHE B C     1 
ATOM   5119 O O     . PHE B 1 320 ? 129.571 175.188 106.821 1.00 64.83  ? 320 PHE B O     1 
ATOM   5120 C CB    . PHE B 1 320 ? 127.265 174.043 105.333 1.00 64.83  ? 320 PHE B CB    1 
ATOM   5121 C CG    . PHE B 1 320 ? 126.345 173.598 104.238 1.00 64.83  ? 320 PHE B CG    1 
ATOM   5122 C CD1   . PHE B 1 320 ? 125.948 174.481 103.250 1.00 64.83  ? 320 PHE B CD1   1 
ATOM   5123 C CD2   . PHE B 1 320 ? 125.895 172.296 104.180 1.00 64.83  ? 320 PHE B CD2   1 
ATOM   5124 C CE1   . PHE B 1 320 ? 125.105 174.075 102.241 1.00 64.83  ? 320 PHE B CE1   1 
ATOM   5125 C CE2   . PHE B 1 320 ? 125.053 171.883 103.171 1.00 64.83  ? 320 PHE B CE2   1 
ATOM   5126 C CZ    . PHE B 1 320 ? 124.658 172.774 102.199 1.00 64.83  ? 320 PHE B CZ    1 
ATOM   5127 N N     . LYS B 1 321 ? 128.390 177.105 106.668 1.00 66.63  ? 321 LYS B N     1 
ATOM   5128 C CA    . LYS B 1 321 ? 129.074 177.747 107.780 1.00 66.63  ? 321 LYS B CA    1 
ATOM   5129 C C     . LYS B 1 321 ? 128.436 177.464 109.132 1.00 66.63  ? 321 LYS B C     1 
ATOM   5130 O O     . LYS B 1 321 ? 129.022 177.827 110.159 1.00 66.63  ? 321 LYS B O     1 
ATOM   5131 C CB    . LYS B 1 321 ? 129.127 179.262 107.562 1.00 66.63  ? 321 LYS B CB    1 
ATOM   5132 C CG    . LYS B 1 321 ? 129.342 179.675 106.117 1.00 66.63  ? 321 LYS B CG    1 
ATOM   5133 C CD    . LYS B 1 321 ? 130.796 179.518 105.708 1.00 66.63  ? 321 LYS B CD    1 
ATOM   5134 C CE    . LYS B 1 321 ? 131.124 180.386 104.504 1.00 66.63  ? 321 LYS B CE    1 
ATOM   5135 N NZ    . LYS B 1 321 ? 132.527 180.194 104.045 1.00 66.63  ? 321 LYS B NZ    1 
ATOM   5136 N N     . SER B 1 322 ? 127.262 176.837 109.171 1.00 68.98  ? 322 SER B N     1 
ATOM   5137 C CA    . SER B 1 322 ? 126.585 176.640 110.444 1.00 68.98  ? 322 SER B CA    1 
ATOM   5138 C C     . SER B 1 322 ? 125.676 175.420 110.395 1.00 68.98  ? 322 SER B C     1 
ATOM   5139 O O     . SER B 1 322 ? 125.148 175.058 109.336 1.00 68.98  ? 322 SER B O     1 
ATOM   5140 C CB    . SER B 1 322 ? 125.772 177.878 110.838 1.00 68.98  ? 322 SER B CB    1 
ATOM   5141 O OG    . SER B 1 322 ? 124.552 177.940 110.123 1.00 68.98  ? 322 SER B OG    1 
ATOM   5142 N N     . TYR B 1 323 ? 125.492 174.804 111.565 1.00 64.52  ? 323 TYR B N     1 
ATOM   5143 C CA    . TYR B 1 323 ? 124.598 173.659 111.671 1.00 64.52  ? 323 TYR B CA    1 
ATOM   5144 C C     . TYR B 1 323 ? 123.165 174.032 111.326 1.00 64.52  ? 323 TYR B C     1 
ATOM   5145 O O     . TYR B 1 323 ? 122.395 173.175 110.887 1.00 64.52  ? 323 TYR B O     1 
ATOM   5146 C CB    . TYR B 1 323 ? 124.660 173.068 113.079 1.00 64.52  ? 323 TYR B CB    1 
ATOM   5147 C CG    . TYR B 1 323 ? 124.025 171.702 113.190 1.00 64.52  ? 323 TYR B CG    1 
ATOM   5148 C CD1   . TYR B 1 323 ? 123.255 171.361 114.293 1.00 64.52  ? 323 TYR B CD1   1 
ATOM   5149 C CD2   . TYR B 1 323 ? 124.196 170.754 112.194 1.00 64.52  ? 323 TYR B CD2   1 
ATOM   5150 C CE1   . TYR B 1 323 ? 122.670 170.114 114.396 1.00 64.52  ? 323 TYR B CE1   1 
ATOM   5151 C CE2   . TYR B 1 323 ? 123.618 169.504 112.290 1.00 64.52  ? 323 TYR B CE2   1 
ATOM   5152 C CZ    . TYR B 1 323 ? 122.857 169.189 113.393 1.00 64.52  ? 323 TYR B CZ    1 
ATOM   5153 O OH    . TYR B 1 323 ? 122.279 167.945 113.491 1.00 64.52  ? 323 TYR B OH    1 
ATOM   5154 N N     . GLU B 1 324 ? 122.789 175.301 111.505 1.00 77.79  ? 324 GLU B N     1 
ATOM   5155 C CA    . GLU B 1 324 ? 121.431 175.719 111.171 1.00 77.79  ? 324 GLU B CA    1 
ATOM   5156 C C     . GLU B 1 324 ? 121.156 175.554 109.680 1.00 77.79  ? 324 GLU B C     1 
ATOM   5157 O O     . GLU B 1 324 ? 120.182 174.903 109.284 1.00 77.79  ? 324 GLU B O     1 
ATOM   5158 C CB    . GLU B 1 324 ? 121.207 177.167 111.608 1.00 77.79  ? 324 GLU B CB    1 
ATOM   5159 C CG    . GLU B 1 324 ? 121.093 177.354 113.114 1.00 77.79  ? 324 GLU B CG    1 
ATOM   5160 C CD    . GLU B 1 324 ? 122.438 177.550 113.786 1.00 77.79  ? 324 GLU B CD    1 
ATOM   5161 O OE1   . GLU B 1 324 ? 123.462 177.593 113.073 1.00 77.79  ? 324 GLU B OE1   1 
ATOM   5162 O OE2   . GLU B 1 324 ? 122.471 177.662 115.030 1.00 77.79  ? 324 GLU B OE2   1 
ATOM   5163 N N     . GLU B 1 325 ? 122.020 176.118 108.832 1.00 73.76  ? 325 GLU B N     1 
ATOM   5164 C CA    . GLU B 1 325 ? 121.822 175.955 107.397 1.00 73.76  ? 325 GLU B CA    1 
ATOM   5165 C C     . GLU B 1 325 ? 122.091 174.519 106.970 1.00 73.76  ? 325 GLU B C     1 
ATOM   5166 O O     . GLU B 1 325 ? 121.453 174.015 106.038 1.00 73.76  ? 325 GLU B O     1 
ATOM   5167 C CB    . GLU B 1 325 ? 122.702 176.931 106.613 1.00 73.76  ? 325 GLU B CB    1 
ATOM   5168 C CG    . GLU B 1 325 ? 124.133 177.037 107.092 1.00 73.76  ? 325 GLU B CG    1 
ATOM   5169 C CD    . GLU B 1 325 ? 124.970 177.934 106.202 1.00 73.76  ? 325 GLU B CD    1 
ATOM   5170 O OE1   . GLU B 1 325 ? 124.382 178.707 105.416 1.00 73.76  ? 325 GLU B OE1   1 
ATOM   5171 O OE2   . GLU B 1 325 ? 126.213 177.867 106.283 1.00 73.76  ? 325 GLU B OE2   1 
ATOM   5172 N N     . LEU B 1 326 ? 123.019 173.837 107.649 1.00 71.63  ? 326 LEU B N     1 
ATOM   5173 C CA    . LEU B 1 326 ? 123.240 172.420 107.369 1.00 71.63  ? 326 LEU B CA    1 
ATOM   5174 C C     . LEU B 1 326 ? 121.954 171.616 107.525 1.00 71.63  ? 326 LEU B C     1 
ATOM   5175 O O     . LEU B 1 326 ? 121.539 170.899 106.606 1.00 71.63  ? 326 LEU B O     1 
ATOM   5176 C CB    . LEU B 1 326 ? 124.326 171.868 108.291 1.00 71.63  ? 326 LEU B CB    1 
ATOM   5177 C CG    . LEU B 1 326 ? 124.721 170.403 108.091 1.00 71.63  ? 326 LEU B CG    1 
ATOM   5178 C CD1   . LEU B 1 326 ? 125.308 170.159 106.721 1.00 71.63  ? 326 LEU B CD1   1 
ATOM   5179 C CD2   . LEU B 1 326 ? 125.701 169.981 109.165 1.00 71.63  ? 326 LEU B CD2   1 
ATOM   5180 N N     . ILE B 1 327 ? 121.298 171.741 108.681 1.00 78.91  ? 327 ILE B N     1 
ATOM   5181 C CA    . ILE B 1 327 ? 120.090 170.970 108.941 1.00 78.91  ? 327 ILE B CA    1 
ATOM   5182 C C     . ILE B 1 327 ? 118.945 171.446 108.057 1.00 78.91  ? 327 ILE B C     1 
ATOM   5183 O O     . ILE B 1 327 ? 118.133 170.633 107.599 1.00 78.91  ? 327 ILE B O     1 
ATOM   5184 C CB    . ILE B 1 327 ? 119.730 171.019 110.440 1.00 78.91  ? 327 ILE B CB    1 
ATOM   5185 C CG1   . ILE B 1 327 ? 118.627 170.014 110.762 1.00 78.91  ? 327 ILE B CG1   1 
ATOM   5186 C CG2   . ILE B 1 327 ? 119.300 172.409 110.872 1.00 78.91  ? 327 ILE B CG2   1 
ATOM   5187 C CD1   . ILE B 1 327 ? 118.445 169.774 112.242 1.00 78.91  ? 327 ILE B CD1   1 
ATOM   5188 N N     . ALA B 1 328 ? 118.864 172.753 107.781 1.00 83.72  ? 328 ALA B N     1 
ATOM   5189 C CA    . ALA B 1 328 ? 117.813 173.255 106.903 1.00 83.72  ? 328 ALA B CA    1 
ATOM   5190 C C     . ALA B 1 328 ? 117.925 172.645 105.511 1.00 83.72  ? 328 ALA B C     1 
ATOM   5191 O O     . ALA B 1 328 ? 116.946 172.117 104.970 1.00 83.72  ? 328 ALA B O     1 
ATOM   5192 C CB    . ALA B 1 328 ? 117.874 174.781 106.832 1.00 83.72  ? 328 ALA B CB    1 
ATOM   5193 N N     . ASP B 1 329 ? 119.123 172.694 104.921 1.00 82.22  ? 329 ASP B N     1 
ATOM   5194 C CA    . ASP B 1 329 ? 119.320 172.114 103.599 1.00 82.22  ? 329 ASP B CA    1 
ATOM   5195 C C     . ASP B 1 329 ? 119.124 170.605 103.610 1.00 82.22  ? 329 ASP B C     1 
ATOM   5196 O O     . ASP B 1 329 ? 118.544 170.053 102.667 1.00 82.22  ? 329 ASP B O     1 
ATOM   5197 C CB    . ASP B 1 329 ? 120.712 172.461 103.073 1.00 82.22  ? 329 ASP B CB    1 
ATOM   5198 C CG    . ASP B 1 329 ? 120.860 173.934 102.751 1.00 82.22  ? 329 ASP B CG    1 
ATOM   5199 O OD1   . ASP B 1 329 ? 119.847 174.572 102.397 1.00 82.22  ? 329 ASP B OD1   1 
ATOM   5200 O OD2   . ASP B 1 329 ? 121.991 174.454 102.849 1.00 82.22  ? 329 ASP B OD2   1 
ATOM   5201 N N     . TYR B 1 330 ? 119.594 169.920 104.657 1.00 74.76  ? 330 TYR B N     1 
ATOM   5202 C CA    . TYR B 1 330 ? 119.460 168.469 104.695 1.00 74.76  ? 330 TYR B CA    1 
ATOM   5203 C C     . TYR B 1 330 ? 117.995 168.059 104.778 1.00 74.76  ? 330 TYR B C     1 
ATOM   5204 O O     . TYR B 1 330 ? 117.574 167.095 104.127 1.00 74.76  ? 330 TYR B O     1 
ATOM   5205 C CB    . TYR B 1 330 ? 120.246 167.900 105.873 1.00 74.76  ? 330 TYR B CB    1 
ATOM   5206 C CG    . TYR B 1 330 ? 120.202 166.394 105.954 1.00 74.76  ? 330 TYR B CG    1 
ATOM   5207 C CD1   . TYR B 1 330 ? 120.964 165.618 105.092 1.00 74.76  ? 330 TYR B CD1   1 
ATOM   5208 C CD2   . TYR B 1 330 ? 119.388 165.747 106.871 1.00 74.76  ? 330 TYR B CD2   1 
ATOM   5209 C CE1   . TYR B 1 330 ? 120.933 164.243 105.153 1.00 74.76  ? 330 TYR B CE1   1 
ATOM   5210 C CE2   . TYR B 1 330 ? 119.348 164.369 106.938 1.00 74.76  ? 330 TYR B CE2   1 
ATOM   5211 C CZ    . TYR B 1 330 ? 120.123 163.623 106.076 1.00 74.76  ? 330 TYR B CZ    1 
ATOM   5212 O OH    . TYR B 1 330 ? 120.089 162.250 106.134 1.00 74.76  ? 330 TYR B OH    1 
ATOM   5213 N N     . GLU B 1 331 ? 117.202 168.775 105.580 1.00 81.74  ? 331 GLU B N     1 
ATOM   5214 C CA    . GLU B 1 331 ? 115.767 168.516 105.630 1.00 81.74  ? 331 GLU B CA    1 
ATOM   5215 C C     . GLU B 1 331 ? 115.099 168.840 104.300 1.00 81.74  ? 331 GLU B C     1 
ATOM   5216 O O     . GLU B 1 331 ? 114.227 168.093 103.841 1.00 81.74  ? 331 GLU B O     1 
ATOM   5217 C CB    . GLU B 1 331 ? 115.128 169.319 106.762 1.00 81.74  ? 331 GLU B CB    1 
ATOM   5218 C CG    . GLU B 1 331 ? 115.318 168.712 108.142 1.00 81.74  ? 331 GLU B CG    1 
ATOM   5219 C CD    . GLU B 1 331 ? 114.468 167.474 108.349 1.00 81.74  ? 331 GLU B CD    1 
ATOM   5220 O OE1   . GLU B 1 331 ? 113.404 167.369 107.703 1.00 81.74  ? 331 GLU B OE1   1 
ATOM   5221 O OE2   . GLU B 1 331 ? 114.857 166.607 109.157 1.00 81.74  ? 331 GLU B OE2   1 
ATOM   5222 N N     . SER B 1 332 ? 115.491 169.948 103.667 1.00 81.99  ? 332 SER B N     1 
ATOM   5223 C CA    . SER B 1 332 ? 114.919 170.303 102.374 1.00 81.99  ? 332 SER B CA    1 
ATOM   5224 C C     . SER B 1 332 ? 115.323 169.329 101.275 1.00 81.99  ? 332 SER B C     1 
ATOM   5225 O O     . SER B 1 332 ? 114.681 169.304 100.220 1.00 81.99  ? 332 SER B O     1 
ATOM   5226 C CB    . SER B 1 332 ? 115.333 171.722 101.986 1.00 81.99  ? 332 SER B CB    1 
ATOM   5227 O OG    . SER B 1 332 ? 116.690 171.762 101.581 1.00 81.99  ? 332 SER B OG    1 
ATOM   5228 N N     . GLY B 1 333 ? 116.364 168.531 101.498 1.00 79.72  ? 333 GLY B N     1 
ATOM   5229 C CA    . GLY B 1 333 ? 116.836 167.593 100.504 1.00 79.72  ? 333 GLY B CA    1 
ATOM   5230 C C     . GLY B 1 333 ? 117.875 168.138 99.551  1.00 79.72  ? 333 GLY B C     1 
ATOM   5231 O O     . GLY B 1 333 ? 118.325 167.401 98.665  1.00 79.72  ? 333 GLY B O     1 
ATOM   5232 N N     . GLU B 1 334 ? 118.270 169.405 99.701  1.00 80.05  ? 334 GLU B N     1 
ATOM   5233 C CA    . GLU B 1 334 ? 119.308 169.963 98.842  1.00 80.05  ? 334 GLU B CA    1 
ATOM   5234 C C     . GLU B 1 334 ? 120.646 169.269 99.058  1.00 80.05  ? 334 GLU B C     1 
ATOM   5235 O O     . GLU B 1 334 ? 121.443 169.157 98.120  1.00 80.05  ? 334 GLU B O     1 
ATOM   5236 C CB    . GLU B 1 334 ? 119.442 171.465 99.089  1.00 80.05  ? 334 GLU B CB    1 
ATOM   5237 C CG    . GLU B 1 334 ? 118.331 172.298 98.470  1.00 80.05  ? 334 GLU B CG    1 
ATOM   5238 C CD    . GLU B 1 334 ? 118.538 173.786 98.671  1.00 80.05  ? 334 GLU B CD    1 
ATOM   5239 O OE1   . GLU B 1 334 ? 119.456 174.351 98.040  1.00 80.05  ? 334 GLU B OE1   1 
ATOM   5240 O OE2   . GLU B 1 334 ? 117.784 174.391 99.461  1.00 80.05  ? 334 GLU B OE2   1 
ATOM   5241 N N     . LEU B 1 335 ? 120.908 168.802 100.274 1.00 70.08  ? 335 LEU B N     1 
ATOM   5242 C CA    . LEU B 1 335 ? 122.123 168.066 100.599 1.00 70.08  ? 335 LEU B CA    1 
ATOM   5243 C C     . LEU B 1 335 ? 121.784 166.584 100.674 1.00 70.08  ? 335 LEU B C     1 
ATOM   5244 O O     . LEU B 1 335 ? 120.919 166.181 101.460 1.00 70.08  ? 335 LEU B O     1 
ATOM   5245 C CB    . LEU B 1 335 ? 122.724 168.550 101.917 1.00 70.08  ? 335 LEU B CB    1 
ATOM   5246 C CG    . LEU B 1 335 ? 124.124 168.024 102.229 1.00 70.08  ? 335 LEU B CG    1 
ATOM   5247 C CD1   . LEU B 1 335 ? 125.119 168.503 101.186 1.00 70.08  ? 335 LEU B CD1   1 
ATOM   5248 C CD2   . LEU B 1 335 ? 124.547 168.455 103.615 1.00 70.08  ? 335 LEU B CD2   1 
ATOM   5249 N N     . HIS B 1 336 ? 122.463 165.782 99.865  1.00 70.07  ? 336 HIS B N     1 
ATOM   5250 C CA    . HIS B 1 336 ? 122.152 164.372 99.739  1.00 70.07  ? 336 HIS B CA    1 
ATOM   5251 C C     . HIS B 1 336 ? 123.325 163.532 100.244 1.00 70.07  ? 336 HIS B C     1 
ATOM   5252 O O     . HIS B 1 336 ? 124.478 163.966 100.158 1.00 70.07  ? 336 HIS B O     1 
ATOM   5253 C CB    . HIS B 1 336 ? 121.849 164.042 98.271  1.00 70.07  ? 336 HIS B CB    1 
ATOM   5254 C CG    . HIS B 1 336 ? 121.353 162.649 98.044  1.00 70.07  ? 336 HIS B CG    1 
ATOM   5255 N ND1   . HIS B 1 336 ? 122.196 161.577 97.849  1.00 70.07  ? 336 HIS B ND1   1 
ATOM   5256 C CD2   . HIS B 1 336 ? 120.094 162.156 97.979  1.00 70.07  ? 336 HIS B CD2   1 
ATOM   5257 C CE1   . HIS B 1 336 ? 121.476 160.483 97.673  1.00 70.07  ? 336 HIS B CE1   1 
ATOM   5258 N NE2   . HIS B 1 336 ? 120.198 160.807 97.749  1.00 70.07  ? 336 HIS B NE2   1 
ATOM   5259 N N     . PRO B 1 337 ? 123.068 162.340 100.796 1.00 67.79  ? 337 PRO B N     1 
ATOM   5260 C CA    . PRO B 1 337 ? 124.175 161.555 101.375 1.00 67.79  ? 337 PRO B CA    1 
ATOM   5261 C C     . PRO B 1 337 ? 125.304 161.255 100.403 1.00 67.79  ? 337 PRO B C     1 
ATOM   5262 O O     . PRO B 1 337 ? 126.468 161.192 100.823 1.00 67.79  ? 337 PRO B O     1 
ATOM   5263 C CB    . PRO B 1 337 ? 123.472 160.274 101.842 1.00 67.79  ? 337 PRO B CB    1 
ATOM   5264 C CG    . PRO B 1 337 ? 122.101 160.725 102.183 1.00 67.79  ? 337 PRO B CG    1 
ATOM   5265 C CD    . PRO B 1 337 ? 121.754 161.780 101.163 1.00 67.79  ? 337 PRO B CD    1 
ATOM   5266 N N     . ALA B 1 338 ? 124.992 161.079 99.113  1.00 74.21  ? 338 ALA B N     1 
ATOM   5267 C CA    . ALA B 1 338 ? 126.023 160.785 98.121  1.00 74.21  ? 338 ALA B CA    1 
ATOM   5268 C C     . ALA B 1 338 ? 127.103 161.856 98.105  1.00 74.21  ? 338 ALA B C     1 
ATOM   5269 O O     . ALA B 1 338 ? 128.273 161.566 97.832  1.00 74.21  ? 338 ALA B O     1 
ATOM   5270 C CB    . ALA B 1 338 ? 125.399 160.653 96.731  1.00 74.21  ? 338 ALA B CB    1 
ATOM   5271 N N     . ASP B 1 339 ? 126.725 163.104 98.372  1.00 72.37  ? 339 ASP B N     1 
ATOM   5272 C CA    . ASP B 1 339 ? 127.710 164.173 98.456  1.00 72.37  ? 339 ASP B CA    1 
ATOM   5273 C C     . ASP B 1 339 ? 128.134 164.435 99.894  1.00 72.37  ? 339 ASP B C     1 
ATOM   5274 O O     . ASP B 1 339 ? 129.233 164.949 100.128 1.00 72.37  ? 339 ASP B O     1 
ATOM   5275 C CB    . ASP B 1 339 ? 127.148 165.448 97.829  1.00 72.37  ? 339 ASP B CB    1 
ATOM   5276 C CG    . ASP B 1 339 ? 126.708 165.244 96.393  1.00 72.37  ? 339 ASP B CG    1 
ATOM   5277 O OD1   . ASP B 1 339 ? 127.234 164.321 95.735  1.00 72.37  ? 339 ASP B OD1   1 
ATOM   5278 O OD2   . ASP B 1 339 ? 125.830 165.998 95.925  1.00 72.37  ? 339 ASP B OD2   1 
ATOM   5279 N N     . LEU B 1 340 ? 127.283 164.088 100.860 1.00 56.79  ? 340 LEU B N     1 
ATOM   5280 C CA    . LEU B 1 340 ? 127.587 164.358 102.261 1.00 56.79  ? 340 LEU B CA    1 
ATOM   5281 C C     . LEU B 1 340 ? 128.719 163.478 102.776 1.00 56.79  ? 340 LEU B C     1 
ATOM   5282 O O     . LEU B 1 340 ? 129.667 163.975 103.394 1.00 56.79  ? 340 LEU B O     1 
ATOM   5283 C CB    . LEU B 1 340 ? 126.335 164.161 103.115 1.00 56.79  ? 340 LEU B CB    1 
ATOM   5284 C CG    . LEU B 1 340 ? 126.539 164.373 104.614 1.00 56.79  ? 340 LEU B CG    1 
ATOM   5285 C CD1   . LEU B 1 340 ? 126.685 165.849 104.916 1.00 56.79  ? 340 LEU B CD1   1 
ATOM   5286 C CD2   . LEU B 1 340 ? 125.388 163.774 105.403 1.00 56.79  ? 340 LEU B CD2   1 
ATOM   5287 N N     . LYS B 1 341 ? 128.636 162.169 102.539 1.00 55.58  ? 341 LYS B N     1 
ATOM   5288 C CA    . LYS B 1 341 ? 129.630 161.264 103.113 1.00 55.58  ? 341 LYS B CA    1 
ATOM   5289 C C     . LYS B 1 341 ? 131.038 161.480 102.571 1.00 55.58  ? 341 LYS B C     1 
ATOM   5290 O O     . LYS B 1 341 ? 131.988 161.423 103.369 1.00 55.58  ? 341 LYS B O     1 
ATOM   5291 C CB    . LYS B 1 341 ? 129.180 159.808 102.957 1.00 55.58  ? 341 LYS B CB    1 
ATOM   5292 C CG    . LYS B 1 341 ? 128.156 159.382 103.986 1.00 55.58  ? 341 LYS B CG    1 
ATOM   5293 C CD    . LYS B 1 341 ? 127.971 157.883 103.967 1.00 55.58  ? 341 LYS B CD    1 
ATOM   5294 C CE    . LYS B 1 341 ? 126.990 157.432 105.028 1.00 55.58  ? 341 LYS B CE    1 
ATOM   5295 N NZ    . LYS B 1 341 ? 127.559 157.585 106.388 1.00 55.58  ? 341 LYS B NZ    1 
ATOM   5296 N N     . PRO B 1 342 ? 131.266 161.676 101.258 1.00 52.30  ? 342 PRO B N     1 
ATOM   5297 C CA    . PRO B 1 342 ? 132.630 161.996 100.810 1.00 52.30  ? 342 PRO B CA    1 
ATOM   5298 C C     . PRO B 1 342 ? 133.214 163.217 101.504 1.00 52.30  ? 342 PRO B C     1 
ATOM   5299 O O     . PRO B 1 342 ? 134.392 163.221 101.875 1.00 52.30  ? 342 PRO B O     1 
ATOM   5300 C CB    . PRO B 1 342 ? 132.465 162.252 99.308  1.00 52.30  ? 342 PRO B CB    1 
ATOM   5301 C CG    . PRO B 1 342 ? 131.200 161.598 98.918  1.00 52.30  ? 342 PRO B CG    1 
ATOM   5302 C CD    . PRO B 1 342 ? 130.425 161.213 100.141 1.00 52.30  ? 342 PRO B CD    1 
ATOM   5303 N N     . ALA B 1 343 ? 132.396 164.255 101.695 1.00 44.71  ? 343 ALA B N     1 
ATOM   5304 C CA    . ALA B 1 343 ? 132.880 165.466 102.350 1.00 44.71  ? 343 ALA B CA    1 
ATOM   5305 C C     . ALA B 1 343 ? 133.243 165.202 103.805 1.00 44.71  ? 343 ALA B C     1 
ATOM   5306 O O     . ALA B 1 343 ? 134.284 165.662 104.289 1.00 44.71  ? 343 ALA B O     1 
ATOM   5307 C CB    . ALA B 1 343 ? 131.831 166.573 102.253 1.00 44.71  ? 343 ALA B CB    1 
ATOM   5308 N N     . LEU B 1 344 ? 132.393 164.460 104.518 1.00 40.92  ? 344 LEU B N     1 
ATOM   5309 C CA    . LEU B 1 344 ? 132.690 164.124 105.906 1.00 40.92  ? 344 LEU B CA    1 
ATOM   5310 C C     . LEU B 1 344 ? 133.945 163.266 106.005 1.00 40.92  ? 344 LEU B C     1 
ATOM   5311 O O     . LEU B 1 344 ? 134.775 163.469 106.898 1.00 40.92  ? 344 LEU B O     1 
ATOM   5312 C CB    . LEU B 1 344 ? 131.496 163.409 106.539 1.00 40.92  ? 344 LEU B CB    1 
ATOM   5313 C CG    . LEU B 1 344 ? 131.754 162.629 107.828 1.00 40.92  ? 344 LEU B CG    1 
ATOM   5314 C CD1   . LEU B 1 344 ? 132.169 163.566 108.948 1.00 40.92  ? 344 LEU B CD1   1 
ATOM   5315 C CD2   . LEU B 1 344 ? 130.524 161.830 108.222 1.00 40.92  ? 344 LEU B CD2   1 
ATOM   5316 N N     . SER B 1 345 ? 134.099 162.302 105.094 1.00 42.80  ? 345 SER B N     1 
ATOM   5317 C CA    . SER B 1 345 ? 135.288 161.458 105.097 1.00 42.80  ? 345 SER B CA    1 
ATOM   5318 C C     . SER B 1 345 ? 136.542 162.280 104.846 1.00 42.80  ? 345 SER B C     1 
ATOM   5319 O O     . SER B 1 345 ? 137.563 162.086 105.515 1.00 42.80  ? 345 SER B O     1 
ATOM   5320 C CB    . SER B 1 345 ? 135.156 160.360 104.043 1.00 42.80  ? 345 SER B CB    1 
ATOM   5321 O OG    . SER B 1 345 ? 133.887 159.739 104.103 1.00 42.80  ? 345 SER B OG    1 
ATOM   5322 N N     . LYS B 1 346 ? 136.486 163.205 103.886 1.00 43.36  ? 346 LYS B N     1 
ATOM   5323 C CA    . LYS B 1 346 ? 137.647 164.039 103.598 1.00 43.36  ? 346 LYS B CA    1 
ATOM   5324 C C     . LYS B 1 346 ? 137.981 164.944 104.775 1.00 43.36  ? 346 LYS B C     1 
ATOM   5325 O O     . LYS B 1 346 ? 139.156 165.139 105.102 1.00 43.36  ? 346 LYS B O     1 
ATOM   5326 C CB    . LYS B 1 346 ? 137.406 164.862 102.335 1.00 43.36  ? 346 LYS B CB    1 
ATOM   5327 C CG    . LYS B 1 346 ? 138.606 165.687 101.904 1.00 43.36  ? 346 LYS B CG    1 
ATOM   5328 C CD    . LYS B 1 346 ? 138.747 165.712 100.391 1.00 43.36  ? 346 LYS B CD    1 
ATOM   5329 C CE    . LYS B 1 346 ? 137.398 165.862 99.711  1.00 43.36  ? 346 LYS B CE    1 
ATOM   5330 N NZ    . LYS B 1 346 ? 136.851 167.239 99.858  1.00 43.36  ? 346 LYS B NZ    1 
ATOM   5331 N N     . SER B 1 347 ? 136.963 165.509 105.426 1.00 33.54  ? 347 SER B N     1 
ATOM   5332 C CA    . SER B 1 347 ? 137.219 166.357 106.586 1.00 33.54  ? 347 SER B CA    1 
ATOM   5333 C C     . SER B 1 347 ? 137.815 165.557 107.738 1.00 33.54  ? 347 SER B C     1 
ATOM   5334 O O     . SER B 1 347 ? 138.742 166.024 108.415 1.00 33.54  ? 347 SER B O     1 
ATOM   5335 C CB    . SER B 1 347 ? 135.931 167.052 107.020 1.00 33.54  ? 347 SER B CB    1 
ATOM   5336 O OG    . SER B 1 347 ? 136.211 168.107 107.921 1.00 33.54  ? 347 SER B OG    1 
ATOM   5337 N N     . LEU B 1 348 ? 137.300 164.349 107.977 1.00 35.22  ? 348 LEU B N     1 
ATOM   5338 C CA    . LEU B 1 348 ? 137.854 163.508 109.032 1.00 35.22  ? 348 LEU B CA    1 
ATOM   5339 C C     . LEU B 1 348 ? 139.287 163.108 108.716 1.00 35.22  ? 348 LEU B C     1 
ATOM   5340 O O     . LEU B 1 348 ? 140.136 163.056 109.612 1.00 35.22  ? 348 LEU B O     1 
ATOM   5341 C CB    . LEU B 1 348 ? 136.981 162.270 109.233 1.00 35.22  ? 348 LEU B CB    1 
ATOM   5342 C CG    . LEU B 1 348 ? 135.865 162.416 110.266 1.00 35.22  ? 348 LEU B CG    1 
ATOM   5343 C CD1   . LEU B 1 348 ? 135.159 161.091 110.481 1.00 35.22  ? 348 LEU B CD1   1 
ATOM   5344 C CD2   . LEU B 1 348 ? 136.419 162.952 111.573 1.00 35.22  ? 348 LEU B CD2   1 
ATOM   5345 N N     . ASN B 1 349 ? 139.578 162.819 107.446 1.00 44.08  ? 349 ASN B N     1 
ATOM   5346 C CA    . ASN B 1 349 ? 140.949 162.514 107.056 1.00 44.08  ? 349 ASN B CA    1 
ATOM   5347 C C     . ASN B 1 349 ? 141.854 163.723 107.245 1.00 44.08  ? 349 ASN B C     1 
ATOM   5348 O O     . ASN B 1 349 ? 143.010 163.582 107.651 1.00 44.08  ? 349 ASN B O     1 
ATOM   5349 C CB    . ASN B 1 349 ? 140.988 162.029 105.609 1.00 44.08  ? 349 ASN B CB    1 
ATOM   5350 C CG    . ASN B 1 349 ? 140.297 160.696 105.429 1.00 44.08  ? 349 ASN B CG    1 
ATOM   5351 O OD1   . ASN B 1 349 ? 140.300 159.857 106.328 1.00 44.08  ? 349 ASN B OD1   1 
ATOM   5352 N ND2   . ASN B 1 349 ? 139.694 160.495 104.264 1.00 44.08  ? 349 ASN B ND2   1 
ATOM   5353 N N     . LYS B 1 350 ? 141.347 164.922 106.950 1.00 39.12  ? 350 LYS B N     1 
ATOM   5354 C CA    . LYS B 1 350 ? 142.130 166.131 107.180 1.00 39.12  ? 350 LYS B CA    1 
ATOM   5355 C C     . LYS B 1 350 ? 142.434 166.313 108.661 1.00 39.12  ? 350 LYS B C     1 
ATOM   5356 O O     . LYS B 1 350 ? 143.536 166.734 109.030 1.00 39.12  ? 350 LYS B O     1 
ATOM   5357 C CB    . LYS B 1 350 ? 141.389 167.349 106.631 1.00 39.12  ? 350 LYS B CB    1 
ATOM   5358 C CG    . LYS B 1 350 ? 142.270 168.570 106.417 1.00 39.12  ? 350 LYS B CG    1 
ATOM   5359 C CD    . LYS B 1 350 ? 141.459 169.765 105.934 1.00 39.12  ? 350 LYS B CD    1 
ATOM   5360 C CE    . LYS B 1 350 ? 140.506 169.380 104.814 1.00 39.12  ? 350 LYS B CE    1 
ATOM   5361 N NZ    . LYS B 1 350 ? 139.606 170.506 104.437 1.00 39.12  ? 350 LYS B NZ    1 
ATOM   5362 N N     . ILE B 1 351 ? 141.463 166.012 109.524 1.00 32.71  ? 351 ILE B N     1 
ATOM   5363 C CA    . ILE B 1 351 ? 141.695 166.121 110.962 1.00 32.71  ? 351 ILE B CA    1 
ATOM   5364 C C     . ILE B 1 351 ? 142.687 165.063 111.433 1.00 32.71  ? 351 ILE B C     1 
ATOM   5365 O O     . ILE B 1 351 ? 143.552 165.336 112.273 1.00 32.71  ? 351 ILE B O     1 
ATOM   5366 C CB    . ILE B 1 351 ? 140.365 166.035 111.733 1.00 32.71  ? 351 ILE B CB    1 
ATOM   5367 C CG1   . ILE B 1 351 ? 139.458 167.208 111.366 1.00 32.71  ? 351 ILE B CG1   1 
ATOM   5368 C CG2   . ILE B 1 351 ? 140.613 166.010 113.231 1.00 32.71  ? 351 ILE B CG2   1 
ATOM   5369 C CD1   . ILE B 1 351 ? 138.047 167.064 111.876 1.00 32.71  ? 351 ILE B CD1   1 
ATOM   5370 N N     . LEU B 1 352 ? 142.581 163.842 110.906 1.00 33.87  ? 352 LEU B N     1 
ATOM   5371 C CA    . LEU B 1 352 ? 143.424 162.745 111.364 1.00 33.87  ? 352 LEU B CA    1 
ATOM   5372 C C     . LEU B 1 352 ? 144.820 162.766 110.755 1.00 33.87  ? 352 LEU B C     1 
ATOM   5373 O O     . LEU B 1 352 ? 145.711 162.080 111.267 1.00 33.87  ? 352 LEU B O     1 
ATOM   5374 C CB    . LEU B 1 352 ? 142.762 161.404 111.046 1.00 33.87  ? 352 LEU B CB    1 
ATOM   5375 C CG    . LEU B 1 352 ? 141.460 161.116 111.789 1.00 33.87  ? 352 LEU B CG    1 
ATOM   5376 C CD1   . LEU B 1 352 ? 140.820 159.827 111.299 1.00 33.87  ? 352 LEU B CD1   1 
ATOM   5377 C CD2   . LEU B 1 352 ? 141.719 161.066 113.272 1.00 33.87  ? 352 LEU B CD2   1 
ATOM   5378 N N     . GLU B 1 353 ? 145.024 163.521 109.678 1.00 39.21  ? 353 GLU B N     1 
ATOM   5379 C CA    . GLU B 1 353 ? 146.329 163.537 109.025 1.00 39.21  ? 353 GLU B CA    1 
ATOM   5380 C C     . GLU B 1 353 ? 147.464 163.982 109.938 1.00 39.21  ? 353 GLU B C     1 
ATOM   5381 O O     . GLU B 1 353 ? 148.550 163.386 109.847 1.00 39.21  ? 353 GLU B O     1 
ATOM   5382 C CB    . GLU B 1 353 ? 146.266 164.410 107.765 1.00 39.21  ? 353 GLU B CB    1 
ATOM   5383 C CG    . GLU B 1 353 ? 147.257 164.003 106.690 1.00 39.21  ? 353 GLU B CG    1 
ATOM   5384 C CD    . GLU B 1 353 ? 147.175 162.527 106.351 1.00 39.21  ? 353 GLU B CD    1 
ATOM   5385 O OE1   . GLU B 1 353 ? 146.056 162.034 106.099 1.00 39.21  ? 353 GLU B OE1   1 
ATOM   5386 O OE2   . GLU B 1 353 ? 148.230 161.859 106.337 1.00 39.21  ? 353 GLU B OE2   1 
ATOM   5387 N N     . PRO B 1 354 ? 147.319 165.007 110.788 1.00 35.79  ? 354 PRO B N     1 
ATOM   5388 C CA    . PRO B 1 354 ? 148.419 165.317 111.714 1.00 35.79  ? 354 PRO B CA    1 
ATOM   5389 C C     . PRO B 1 354 ? 148.827 164.142 112.583 1.00 35.79  ? 354 PRO B C     1 
ATOM   5390 O O     . PRO B 1 354 ? 150.024 163.949 112.817 1.00 35.79  ? 354 PRO B O     1 
ATOM   5391 C CB    . PRO B 1 354 ? 147.851 166.474 112.545 1.00 35.79  ? 354 PRO B CB    1 
ATOM   5392 C CG    . PRO B 1 354 ? 146.932 167.159 111.615 1.00 35.79  ? 354 PRO B CG    1 
ATOM   5393 C CD    . PRO B 1 354 ? 146.291 166.064 110.805 1.00 35.79  ? 354 PRO B CD    1 
ATOM   5394 N N     . VAL B 1 355 ? 147.873 163.332 113.046 1.00 34.68  ? 355 VAL B N     1 
ATOM   5395 C CA    . VAL B 1 355 ? 148.213 162.196 113.901 1.00 34.68  ? 355 VAL B CA    1 
ATOM   5396 C C     . VAL B 1 355 ? 149.039 161.173 113.131 1.00 34.68  ? 355 VAL B C     1 
ATOM   5397 O O     . VAL B 1 355 ? 150.085 160.709 113.604 1.00 34.68  ? 355 VAL B O     1 
ATOM   5398 C CB    . VAL B 1 355 ? 146.937 161.566 114.485 1.00 34.68  ? 355 VAL B CB    1 
ATOM   5399 C CG1   . VAL B 1 355 ? 147.207 160.144 114.951 1.00 34.68  ? 355 VAL B CG1   1 
ATOM   5400 C CG2   . VAL B 1 355 ? 146.413 162.410 115.630 1.00 34.68  ? 355 VAL B CG2   1 
ATOM   5401 N N     . ARG B 1 356 ? 148.579 160.803 111.933 1.00 40.25  ? 356 ARG B N     1 
ATOM   5402 C CA    . ARG B 1 356 ? 149.306 159.821 111.136 1.00 40.25  ? 356 ARG B CA    1 
ATOM   5403 C C     . ARG B 1 356 ? 150.684 160.339 110.750 1.00 40.25  ? 356 ARG B C     1 
ATOM   5404 O O     . ARG B 1 356 ? 151.671 159.600 110.811 1.00 40.25  ? 356 ARG B O     1 
ATOM   5405 C CB    . ARG B 1 356 ? 148.500 159.453 109.890 1.00 40.25  ? 356 ARG B CB    1 
ATOM   5406 C CG    . ARG B 1 356 ? 147.194 158.734 110.182 1.00 40.25  ? 356 ARG B CG    1 
ATOM   5407 C CD    . ARG B 1 356 ? 146.805 157.824 109.031 1.00 40.25  ? 356 ARG B CD    1 
ATOM   5408 N NE    . ARG B 1 356 ? 145.365 157.604 108.955 1.00 40.25  ? 356 ARG B NE    1 
ATOM   5409 C CZ    . ARG B 1 356 ? 144.508 158.438 108.381 1.00 40.25  ? 356 ARG B CZ    1 
ATOM   5410 N NH1   . ARG B 1 356 ? 144.909 159.573 107.834 1.00 40.25  ? 356 ARG B NH1   1 
ATOM   5411 N NH2   . ARG B 1 356 ? 143.217 158.123 108.354 1.00 40.25  ? 356 ARG B NH2   1 
ATOM   5412 N N     . GLU B 1 357 ? 150.772 161.611 110.355 1.00 52.56  ? 357 GLU B N     1 
ATOM   5413 C CA    . GLU B 1 357 ? 152.061 162.191 109.992 1.00 52.56  ? 357 GLU B CA    1 
ATOM   5414 C C     . GLU B 1 357 ? 153.011 162.218 111.183 1.00 52.56  ? 357 GLU B C     1 
ATOM   5415 O O     . GLU B 1 357 ? 154.195 161.887 111.049 1.00 52.56  ? 357 GLU B O     1 
ATOM   5416 C CB    . GLU B 1 357 ? 151.854 163.598 109.432 1.00 52.56  ? 357 GLU B CB    1 
ATOM   5417 C CG    . GLU B 1 357 ? 153.120 164.426 109.325 1.00 52.56  ? 357 GLU B CG    1 
ATOM   5418 C CD    . GLU B 1 357 ? 152.830 165.910 109.208 1.00 52.56  ? 357 GLU B CD    1 
ATOM   5419 O OE1   . GLU B 1 357 ? 152.450 166.524 110.226 1.00 52.56  ? 357 GLU B OE1   1 
ATOM   5420 O OE2   . GLU B 1 357 ? 152.980 166.460 108.097 1.00 52.56  ? 357 GLU B OE2   1 
ATOM   5421 N N     . HIS B 1 358 ? 152.507 162.598 112.360 1.00 46.65  ? 358 HIS B N     1 
ATOM   5422 C CA    . HIS B 1 358 ? 153.337 162.628 113.558 1.00 46.65  ? 358 HIS B CA    1 
ATOM   5423 C C     . HIS B 1 358 ? 153.844 161.238 113.913 1.00 46.65  ? 358 HIS B C     1 
ATOM   5424 O O     . HIS B 1 358 ? 155.022 161.066 114.249 1.00 46.65  ? 358 HIS B O     1 
ATOM   5425 C CB    . HIS B 1 358 ? 152.539 163.226 114.716 1.00 46.65  ? 358 HIS B CB    1 
ATOM   5426 C CG    . HIS B 1 358 ? 153.260 163.219 116.026 1.00 46.65  ? 358 HIS B CG    1 
ATOM   5427 N ND1   . HIS B 1 358 ? 153.282 162.119 116.857 1.00 46.65  ? 358 HIS B ND1   1 
ATOM   5428 C CD2   . HIS B 1 358 ? 153.968 164.183 116.660 1.00 46.65  ? 358 HIS B CD2   1 
ATOM   5429 C CE1   . HIS B 1 358 ? 153.981 162.403 117.941 1.00 46.65  ? 358 HIS B CE1   1 
ATOM   5430 N NE2   . HIS B 1 358 ? 154.408 163.650 117.847 1.00 46.65  ? 358 HIS B NE2   1 
ATOM   5431 N N     . PHE B 1 359 ? 152.975 160.229 113.836 1.00 46.94  ? 359 PHE B N     1 
ATOM   5432 C CA    . PHE B 1 359 ? 153.395 158.882 114.201 1.00 46.94  ? 359 PHE B CA    1 
ATOM   5433 C C     . PHE B 1 359 ? 154.276 158.235 113.139 1.00 46.94  ? 359 PHE B C     1 
ATOM   5434 O O     . PHE B 1 359 ? 155.046 157.326 113.465 1.00 46.94  ? 359 PHE B O     1 
ATOM   5435 C CB    . PHE B 1 359 ? 152.174 158.013 114.496 1.00 46.94  ? 359 PHE B CB    1 
ATOM   5436 C CG    . PHE B 1 359 ? 151.712 158.096 115.923 1.00 46.94  ? 359 PHE B CG    1 
ATOM   5437 C CD1   . PHE B 1 359 ? 151.550 159.325 116.539 1.00 46.94  ? 359 PHE B CD1   1 
ATOM   5438 C CD2   . PHE B 1 359 ? 151.458 156.950 116.652 1.00 46.94  ? 359 PHE B CD2   1 
ATOM   5439 C CE1   . PHE B 1 359 ? 151.134 159.408 117.852 1.00 46.94  ? 359 PHE B CE1   1 
ATOM   5440 C CE2   . PHE B 1 359 ? 151.042 157.027 117.964 1.00 46.94  ? 359 PHE B CE2   1 
ATOM   5441 C CZ    . PHE B 1 359 ? 150.879 158.257 118.565 1.00 46.94  ? 359 PHE B CZ    1 
ATOM   5442 N N     . ARG B 1 360 ? 154.180 158.672 111.882 1.00 52.88  ? 360 ARG B N     1 
ATOM   5443 C CA    . ARG B 1 360 ? 155.120 158.210 110.867 1.00 52.88  ? 360 ARG B CA    1 
ATOM   5444 C C     . ARG B 1 360 ? 156.474 158.894 110.991 1.00 52.88  ? 360 ARG B C     1 
ATOM   5445 O O     . ARG B 1 360 ? 157.503 158.275 110.699 1.00 52.88  ? 360 ARG B O     1 
ATOM   5446 C CB    . ARG B 1 360 ? 154.553 158.445 109.465 1.00 52.88  ? 360 ARG B CB    1 
ATOM   5447 C CG    . ARG B 1 360 ? 153.333 157.607 109.119 1.00 52.88  ? 360 ARG B CG    1 
ATOM   5448 C CD    . ARG B 1 360 ? 153.693 156.441 108.215 1.00 52.88  ? 360 ARG B CD    1 
ATOM   5449 N NE    . ARG B 1 360 ? 152.524 155.644 107.865 1.00 52.88  ? 360 ARG B NE    1 
ATOM   5450 C CZ    . ARG B 1 360 ? 151.963 154.745 108.662 1.00 52.88  ? 360 ARG B CZ    1 
ATOM   5451 N NH1   . ARG B 1 360 ? 152.442 154.495 109.869 1.00 52.88  ? 360 ARG B NH1   1 
ATOM   5452 N NH2   . ARG B 1 360 ? 150.894 154.079 108.236 1.00 52.88  ? 360 ARG B NH2   1 
ATOM   5453 N N     . LYS B 1 361 ? 156.498 160.156 111.419 1.00 56.97  ? 361 LYS B N     1 
ATOM   5454 C CA    . LYS B 1 361 ? 157.737 160.922 111.431 1.00 56.97  ? 361 LYS B CA    1 
ATOM   5455 C C     . LYS B 1 361 ? 158.535 160.731 112.717 1.00 56.97  ? 361 LYS B C     1 
ATOM   5456 O O     . LYS B 1 361 ? 159.741 160.475 112.663 1.00 56.97  ? 361 LYS B O     1 
ATOM   5457 C CB    . LYS B 1 361 ? 157.432 162.406 111.210 1.00 56.97  ? 361 LYS B CB    1 
ATOM   5458 C CG    . LYS B 1 361 ? 157.109 162.752 109.766 1.00 56.97  ? 361 LYS B CG    1 
ATOM   5459 C CD    . LYS B 1 361 ? 156.784 164.226 109.604 1.00 56.97  ? 361 LYS B CD    1 
ATOM   5460 C CE    . LYS B 1 361 ? 156.764 164.622 108.137 1.00 56.97  ? 361 LYS B CE    1 
ATOM   5461 N NZ    . LYS B 1 361 ? 155.995 165.875 107.906 1.00 56.97  ? 361 LYS B NZ    1 
ATOM   5462 N N     . ASP B 1 362 ? 157.892 160.855 113.877 1.00 68.33  ? 362 ASP B N     1 
ATOM   5463 C CA    . ASP B 1 362 ? 158.612 160.730 115.136 1.00 68.33  ? 362 ASP B CA    1 
ATOM   5464 C C     . ASP B 1 362 ? 158.945 159.269 115.413 1.00 68.33  ? 362 ASP B C     1 
ATOM   5465 O O     . ASP B 1 362 ? 158.063 158.404 115.407 1.00 68.33  ? 362 ASP B O     1 
ATOM   5466 C CB    . ASP B 1 362 ? 157.787 161.312 116.281 1.00 68.33  ? 362 ASP B CB    1 
ATOM   5467 C CG    . ASP B 1 362 ? 158.530 161.292 117.603 1.00 68.33  ? 362 ASP B CG    1 
ATOM   5468 O OD1   . ASP B 1 362 ? 159.779 161.273 117.584 1.00 68.33  ? 362 ASP B OD1   1 
ATOM   5469 O OD2   . ASP B 1 362 ? 157.866 161.295 118.660 1.00 68.33  ? 362 ASP B OD2   1 
ATOM   5470 N N     . SER B 1 363 ? 160.230 158.998 115.659 1.00 77.24  ? 363 SER B N     1 
ATOM   5471 C CA    . SER B 1 363 ? 160.655 157.636 115.962 1.00 77.24  ? 363 SER B CA    1 
ATOM   5472 C C     . SER B 1 363 ? 160.032 157.141 117.260 1.00 77.24  ? 363 SER B C     1 
ATOM   5473 O O     . SER B 1 363 ? 159.622 155.979 117.356 1.00 77.24  ? 363 SER B O     1 
ATOM   5474 C CB    . SER B 1 363 ? 162.180 157.567 116.037 1.00 77.24  ? 363 SER B CB    1 
ATOM   5475 O OG    . SER B 1 363 ? 162.693 158.562 116.907 1.00 77.24  ? 363 SER B OG    1 
ATOM   5476 N N     . ASN B 1 364 ? 159.962 158.008 118.273 1.00 75.62  ? 364 ASN B N     1 
ATOM   5477 C CA    . ASN B 1 364 ? 159.346 157.619 119.537 1.00 75.62  ? 364 ASN B CA    1 
ATOM   5478 C C     . ASN B 1 364 ? 157.871 157.288 119.353 1.00 75.62  ? 364 ASN B C     1 
ATOM   5479 O O     . ASN B 1 364 ? 157.376 156.299 119.906 1.00 75.62  ? 364 ASN B O     1 
ATOM   5480 C CB    . ASN B 1 364 ? 159.523 158.732 120.570 1.00 75.62  ? 364 ASN B CB    1 
ATOM   5481 C CG    . ASN B 1 364 ? 158.865 158.406 121.894 1.00 75.62  ? 364 ASN B CG    1 
ATOM   5482 O OD1   . ASN B 1 364 ? 159.079 157.334 122.459 1.00 75.62  ? 364 ASN B OD1   1 
ATOM   5483 N ND2   . ASN B 1 364 ? 158.057 159.332 122.396 1.00 75.62  ? 364 ASN B ND2   1 
ATOM   5484 N N     . ALA B 1 365 ? 157.154 158.101 118.575 1.00 65.69  ? 365 ALA B N     1 
ATOM   5485 C CA    . ALA B 1 365 ? 155.745 157.824 118.319 1.00 65.69  ? 365 ALA B CA    1 
ATOM   5486 C C     . ALA B 1 365 ? 155.567 156.525 117.543 1.00 65.69  ? 365 ALA B C     1 
ATOM   5487 O O     . ALA B 1 365 ? 154.650 155.745 117.828 1.00 65.69  ? 365 ALA B O     1 
ATOM   5488 C CB    . ALA B 1 365 ? 155.109 158.992 117.567 1.00 65.69  ? 365 ALA B CB    1 
ATOM   5489 N N     . LYS B 1 366 ? 156.430 156.279 116.554 1.00 72.81  ? 366 LYS B N     1 
ATOM   5490 C CA    . LYS B 1 366 ? 156.344 155.036 115.795 1.00 72.81  ? 366 LYS B CA    1 
ATOM   5491 C C     . LYS B 1 366 ? 156.599 153.829 116.689 1.00 72.81  ? 366 LYS B C     1 
ATOM   5492 O O     . LYS B 1 366 ? 155.905 152.810 116.587 1.00 72.81  ? 366 LYS B O     1 
ATOM   5493 C CB    . LYS B 1 366 ? 157.333 155.062 114.630 1.00 72.81  ? 366 LYS B CB    1 
ATOM   5494 C CG    . LYS B 1 366 ? 157.298 153.817 113.761 1.00 72.81  ? 366 LYS B CG    1 
ATOM   5495 C CD    . LYS B 1 366 ? 156.001 153.738 112.973 1.00 72.81  ? 366 LYS B CD    1 
ATOM   5496 C CE    . LYS B 1 366 ? 156.002 152.554 112.020 1.00 72.81  ? 366 LYS B CE    1 
ATOM   5497 N NZ    . LYS B 1 366 ? 154.710 152.429 111.292 1.00 72.81  ? 366 LYS B NZ    1 
ATOM   5498 N N     . GLU B 1 367 ? 157.593 153.928 117.575 1.00 69.12  ? 367 GLU B N     1 
ATOM   5499 C CA    . GLU B 1 367 ? 157.871 152.838 118.503 1.00 69.12  ? 367 GLU B CA    1 
ATOM   5500 C C     . GLU B 1 367 ? 156.708 152.622 119.461 1.00 69.12  ? 367 GLU B C     1 
ATOM   5501 O O     . GLU B 1 367 ? 156.374 151.479 119.793 1.00 69.12  ? 367 GLU B O     1 
ATOM   5502 C CB    . GLU B 1 367 ? 159.160 153.121 119.275 1.00 69.12  ? 367 GLU B CB    1 
ATOM   5503 C CG    . GLU B 1 367 ? 159.727 151.910 119.995 1.00 69.12  ? 367 GLU B CG    1 
ATOM   5504 C CD    . GLU B 1 367 ? 160.135 150.805 119.041 1.00 69.12  ? 367 GLU B CD    1 
ATOM   5505 O OE1   . GLU B 1 367 ? 160.736 151.117 117.991 1.00 69.12  ? 367 GLU B OE1   1 
ATOM   5506 O OE2   . GLU B 1 367 ? 159.857 149.626 119.341 1.00 69.12  ? 367 GLU B OE2   1 
ATOM   5507 N N     . LEU B 1 368 ? 156.083 153.708 119.922 1.00 62.99  ? 368 LEU B N     1 
ATOM   5508 C CA    . LEU B 1 368 ? 154.912 153.581 120.784 1.00 62.99  ? 368 LEU B CA    1 
ATOM   5509 C C     . LEU B 1 368 ? 153.779 152.863 120.062 1.00 62.99  ? 368 LEU B C     1 
ATOM   5510 O O     . LEU B 1 368 ? 153.135 151.970 120.624 1.00 62.99  ? 368 LEU B O     1 
ATOM   5511 C CB    . LEU B 1 368 ? 154.456 154.961 121.259 1.00 62.99  ? 368 LEU B CB    1 
ATOM   5512 C CG    . LEU B 1 368 ? 155.220 155.586 122.426 1.00 62.99  ? 368 LEU B CG    1 
ATOM   5513 C CD1   . LEU B 1 368 ? 154.997 157.087 122.463 1.00 62.99  ? 368 LEU B CD1   1 
ATOM   5514 C CD2   . LEU B 1 368 ? 154.797 154.952 123.736 1.00 62.99  ? 368 LEU B CD2   1 
ATOM   5515 N N     . LEU B 1 369 ? 153.525 153.243 118.807 1.00 67.02  ? 369 LEU B N     1 
ATOM   5516 C CA    . LEU B 1 369 ? 152.469 152.592 118.038 1.00 67.02  ? 369 LEU B CA    1 
ATOM   5517 C C     . LEU B 1 369 ? 152.778 151.113 117.844 1.00 67.02  ? 369 LEU B C     1 
ATOM   5518 O O     . LEU B 1 369 ? 151.888 150.262 117.969 1.00 67.02  ? 369 LEU B O     1 
ATOM   5519 C CB    . LEU B 1 369 ? 152.295 153.297 116.690 1.00 67.02  ? 369 LEU B CB    1 
ATOM   5520 C CG    . LEU B 1 369 ? 150.990 153.178 115.888 1.00 67.02  ? 369 LEU B CG    1 
ATOM   5521 C CD1   . LEU B 1 369 ? 151.034 154.111 114.687 1.00 67.02  ? 369 LEU B CD1   1 
ATOM   5522 C CD2   . LEU B 1 369 ? 150.693 151.760 115.425 1.00 67.02  ? 369 LEU B CD2   1 
ATOM   5523 N N     . LYS B 1 370 ? 154.038 150.788 117.542 1.00 75.91  ? 370 LYS B N     1 
ATOM   5524 C CA    . LYS B 1 370 ? 154.422 149.391 117.369 1.00 75.91  ? 370 LYS B CA    1 
ATOM   5525 C C     . LYS B 1 370 ? 154.237 148.604 118.660 1.00 75.91  ? 370 LYS B C     1 
ATOM   5526 O O     . LYS B 1 370 ? 153.745 147.469 118.639 1.00 75.91  ? 370 LYS B O     1 
ATOM   5527 C CB    . LYS B 1 370 ? 155.870 149.303 116.886 1.00 75.91  ? 370 LYS B CB    1 
ATOM   5528 C CG    . LYS B 1 370 ? 156.420 147.888 116.817 1.00 75.91  ? 370 LYS B CG    1 
ATOM   5529 C CD    . LYS B 1 370 ? 155.547 147.000 115.945 1.00 75.91  ? 370 LYS B CD    1 
ATOM   5530 C CE    . LYS B 1 370 ? 155.917 145.536 116.104 1.00 75.91  ? 370 LYS B CE    1 
ATOM   5531 N NZ    . LYS B 1 370 ? 154.940 144.649 115.417 1.00 75.91  ? 370 LYS B NZ    1 
ATOM   5532 N N     . ARG B 1 371 ? 154.625 149.188 119.796 1.00 65.34  ? 371 ARG B N     1 
ATOM   5533 C CA    . ARG B 1 371 ? 154.463 148.500 121.071 1.00 65.34  ? 371 ARG B CA    1 
ATOM   5534 C C     . ARG B 1 371 ? 152.993 148.259 121.387 1.00 65.34  ? 371 ARG B C     1 
ATOM   5535 O O     . ARG B 1 371 ? 152.620 147.171 121.840 1.00 65.34  ? 371 ARG B O     1 
ATOM   5536 C CB    . ARG B 1 371 ? 155.132 149.297 122.190 1.00 65.34  ? 371 ARG B CB    1 
ATOM   5537 C CG    . ARG B 1 371 ? 156.648 149.272 122.139 1.00 65.34  ? 371 ARG B CG    1 
ATOM   5538 C CD    . ARG B 1 371 ? 157.247 149.128 123.527 1.00 65.34  ? 371 ARG B CD    1 
ATOM   5539 N NE    . ARG B 1 371 ? 156.904 150.249 124.393 1.00 65.34  ? 371 ARG B NE    1 
ATOM   5540 C CZ    . ARG B 1 371 ? 157.635 151.347 124.517 1.00 65.34  ? 371 ARG B CZ    1 
ATOM   5541 N NH1   . ARG B 1 371 ? 158.759 151.509 123.840 1.00 65.34  ? 371 ARG B NH1   1 
ATOM   5542 N NH2   . ARG B 1 371 ? 157.229 152.307 125.344 1.00 65.34  ? 371 ARG B NH2   1 
ATOM   5543 N N     . VAL B 1 372 ? 152.142 149.261 121.151 1.00 60.42  ? 372 VAL B N     1 
ATOM   5544 C CA    . VAL B 1 372 ? 150.713 149.085 121.405 1.00 60.42  ? 372 VAL B CA    1 
ATOM   5545 C C     . VAL B 1 372 ? 150.131 148.013 120.492 1.00 60.42  ? 372 VAL B C     1 
ATOM   5546 O O     . VAL B 1 372 ? 149.327 147.180 120.926 1.00 60.42  ? 372 VAL B O     1 
ATOM   5547 C CB    . VAL B 1 372 ? 149.963 150.421 121.263 1.00 60.42  ? 372 VAL B CB    1 
ATOM   5548 C CG1   . VAL B 1 372 ? 148.499 150.237 121.616 1.00 60.42  ? 372 VAL B CG1   1 
ATOM   5549 C CG2   . VAL B 1 372 ? 150.573 151.453 122.184 1.00 60.42  ? 372 VAL B CG2   1 
ATOM   5550 N N     . LYS B 1 373 ? 150.522 148.015 119.215 1.00 69.61  ? 373 LYS B N     1 
ATOM   5551 C CA    . LYS B 1 373 ? 150.062 146.962 118.316 1.00 69.61  ? 373 LYS B CA    1 
ATOM   5552 C C     . LYS B 1 373 ? 150.590 145.596 118.736 1.00 69.61  ? 373 LYS B C     1 
ATOM   5553 O O     . LYS B 1 373 ? 149.973 144.572 118.424 1.00 69.61  ? 373 LYS B O     1 
ATOM   5554 C CB    . LYS B 1 373 ? 150.473 147.270 116.877 1.00 69.61  ? 373 LYS B CB    1 
ATOM   5555 C CG    . LYS B 1 373 ? 149.523 148.203 116.148 1.00 69.61  ? 373 LYS B CG    1 
ATOM   5556 C CD    . LYS B 1 373 ? 149.848 148.268 114.666 1.00 69.61  ? 373 LYS B CD    1 
ATOM   5557 C CE    . LYS B 1 373 ? 148.767 149.007 113.895 1.00 69.61  ? 373 LYS B CE    1 
ATOM   5558 N NZ    . LYS B 1 373 ? 149.172 149.265 112.486 1.00 69.61  ? 373 LYS B NZ    1 
ATOM   5559 N N     . ALA B 1 374 ? 151.723 145.560 119.440 1.00 71.59  ? 374 ALA B N     1 
ATOM   5560 C CA    . ALA B 1 374 ? 152.271 144.293 119.908 1.00 71.59  ? 374 ALA B CA    1 
ATOM   5561 C C     . ALA B 1 374 ? 151.495 143.724 121.088 1.00 71.59  ? 374 ALA B C     1 
ATOM   5562 O O     . ALA B 1 374 ? 151.572 142.516 121.337 1.00 71.59  ? 374 ALA B O     1 
ATOM   5563 C CB    . ALA B 1 374 ? 153.742 144.464 120.288 1.00 71.59  ? 374 ALA B CB    1 
ATOM   5564 N N     . TYR B 1 375 ? 150.751 144.554 121.813 1.00 65.28  ? 375 TYR B N     1 
ATOM   5565 C CA    . TYR B 1 375 ? 149.994 144.103 122.973 1.00 65.28  ? 375 TYR B CA    1 
ATOM   5566 C C     . TYR B 1 375 ? 148.626 143.606 122.524 1.00 65.28  ? 375 TYR B C     1 
ATOM   5567 O O     . TYR B 1 375 ? 147.859 144.354 121.908 1.00 65.28  ? 375 TYR B O     1 
ATOM   5568 C CB    . TYR B 1 375 ? 149.844 145.225 124.000 1.00 65.28  ? 375 TYR B CB    1 
ATOM   5569 C CG    . TYR B 1 375 ? 151.149 145.853 124.430 1.00 65.28  ? 375 TYR B CG    1 
ATOM   5570 C CD1   . TYR B 1 375 ? 152.272 145.074 124.671 1.00 65.28  ? 375 TYR B CD1   1 
ATOM   5571 C CD2   . TYR B 1 375 ? 151.254 147.225 124.608 1.00 65.28  ? 375 TYR B CD2   1 
ATOM   5572 C CE1   . TYR B 1 375 ? 153.465 145.646 125.068 1.00 65.28  ? 375 TYR B CE1   1 
ATOM   5573 C CE2   . TYR B 1 375 ? 152.443 147.805 125.004 1.00 65.28  ? 375 TYR B CE2   1 
ATOM   5574 C CZ    . TYR B 1 375 ? 153.544 147.012 125.233 1.00 65.28  ? 375 TYR B CZ    1 
ATOM   5575 O OH    . TYR B 1 375 ? 154.729 147.587 125.629 1.00 65.28  ? 375 TYR B OH    1 
ATOM   5576 N N     . ARG B 1 376 ? 148.325 142.348 122.830 1.00 100.03 ? 376 ARG B N     1 
ATOM   5577 C CA    . ARG B 1 376 ? 147.017 141.784 122.531 1.00 100.03 ? 376 ARG B CA    1 
ATOM   5578 C C     . ARG B 1 376 ? 146.032 142.135 123.638 1.00 100.03 ? 376 ARG B C     1 
ATOM   5579 O O     . ARG B 1 376 ? 146.396 142.200 124.816 1.00 100.03 ? 376 ARG B O     1 
ATOM   5580 C CB    . ARG B 1 376 ? 147.115 140.266 122.368 1.00 100.03 ? 376 ARG B CB    1 
ATOM   5581 C CG    . ARG B 1 376 ? 145.832 139.600 121.895 1.00 100.03 ? 376 ARG B CG    1 
ATOM   5582 C CD    . ARG B 1 376 ? 146.014 138.099 121.741 1.00 100.03 ? 376 ARG B CD    1 
ATOM   5583 N NE    . ARG B 1 376 ? 146.361 137.457 123.003 1.00 100.03 ? 376 ARG B NE    1 
ATOM   5584 C CZ    . ARG B 1 376 ? 145.476 137.040 123.899 1.00 100.03 ? 376 ARG B CZ    1 
ATOM   5585 N NH1   . ARG B 1 376 ? 144.175 137.181 123.704 1.00 100.03 ? 376 ARG B NH1   1 
ATOM   5586 N NH2   . ARG B 1 376 ? 145.908 136.466 125.018 1.00 100.03 ? 376 ARG B NH2   1 
ATOM   5587 N N     . VAL B 1 377 ? 144.777 142.367 123.252 1.00 101.72 ? 377 VAL B N     1 
ATOM   5588 C CA    . VAL B 1 377 ? 143.752 142.742 124.218 1.00 101.72 ? 377 VAL B CA    1 
ATOM   5589 C C     . VAL B 1 377 ? 143.434 141.552 125.112 1.00 101.72 ? 377 VAL B C     1 
ATOM   5590 O O     . VAL B 1 377 ? 143.168 140.443 124.630 1.00 101.72 ? 377 VAL B O     1 
ATOM   5591 C CB    . VAL B 1 377 ? 142.493 143.249 123.499 1.00 101.72 ? 377 VAL B CB    1 
ATOM   5592 C CG1   . VAL B 1 377 ? 141.483 143.777 124.506 1.00 101.72 ? 377 VAL B CG1   1 
ATOM   5593 C CG2   . VAL B 1 377 ? 142.859 144.324 122.486 1.00 101.72 ? 377 VAL B CG2   1 
ATOM   5594 N N     . THR B 1 378 ? 143.461 141.777 126.424 1.00 98.88  ? 378 THR B N     1 
ATOM   5595 C CA    . THR B 1 378 ? 143.160 140.750 127.414 1.00 98.88  ? 378 THR B CA    1 
ATOM   5596 C C     . THR B 1 378 ? 141.989 141.220 128.264 1.00 98.88  ? 378 THR B C     1 
ATOM   5597 O O     . THR B 1 378 ? 142.113 142.196 129.011 1.00 98.88  ? 378 THR B O     1 
ATOM   5598 C CB    . THR B 1 378 ? 144.377 140.456 128.294 1.00 98.88  ? 378 THR B CB    1 
ATOM   5599 O OG1   . THR B 1 378 ? 145.436 139.923 127.489 1.00 98.88  ? 378 THR B OG1   1 
ATOM   5600 C CG2   . THR B 1 378 ? 144.019 139.454 129.381 1.00 98.88  ? 378 THR B CG2   1 
ATOM   5601 N N     . LYS B 1 379 ? 140.860 140.528 128.149 1.00 109.27 ? 379 LYS B N     1 
ATOM   5602 C CA    . LYS B 1 379 ? 139.668 140.866 128.920 1.00 109.27 ? 379 LYS B CA    1 
ATOM   5603 C C     . LYS B 1 379 ? 138.957 139.607 129.405 1.00 109.27 ? 379 LYS B C     1 
ATOM   5604 O O     . LYS B 1 379 ? 139.244 138.500 128.949 0.00 109.27 ? 379 LYS B O     1 
ATOM   5605 C CB    . LYS B 1 379 ? 138.710 141.724 128.090 1.00 109.27 ? 379 LYS B CB    1 
ATOM   5606 C CG    . LYS B 1 379 ? 139.181 143.152 127.868 1.00 109.27 ? 379 LYS B CG    1 
ATOM   5607 C CD    . LYS B 1 379 ? 138.063 144.026 127.322 1.00 109.27 ? 379 LYS B CD    1 
ATOM   5608 C CE    . LYS B 1 379 ? 137.798 143.736 125.854 1.00 109.27 ? 379 LYS B CE    1 
ATOM   5609 N NZ    . LYS B 1 379 ? 136.776 144.657 125.285 1.00 109.27 ? 379 LYS B NZ    1 
ATOM   5610 O OXT   . LYS B 1 379 ? 138.077 139.667 130.264 0.00 109.27 ? 379 LYS B OXT   1 
ATOM   5611 O "O5'" . C   C 2 1   ? 132.450 123.416 103.174 1.00 184.67 ? 1   C   C "O5'" 1 
ATOM   5612 C "C5'" . C   C 2 1   ? 131.256 122.987 103.812 1.00 184.67 ? 1   C   C "C5'" 1 
ATOM   5613 C "C4'" . C   C 2 1   ? 130.336 122.281 102.848 1.00 184.67 ? 1   C   C "C4'" 1 
ATOM   5614 O "O4'" . C   C 2 1   ? 129.965 123.182 101.776 1.00 184.67 ? 1   C   C "O4'" 1 
ATOM   5615 C "C3'" . C   C 2 1   ? 130.919 121.073 102.131 1.00 184.67 ? 1   C   C "C3'" 1 
ATOM   5616 O "O3'" . C   C 2 1   ? 130.884 119.899 102.925 1.00 184.67 ? 1   C   C "O3'" 1 
ATOM   5617 C "C2'" . C   C 2 1   ? 130.068 120.983 100.869 1.00 184.67 ? 1   C   C "C2'" 1 
ATOM   5618 O "O2'" . C   C 2 1   ? 128.833 120.338 101.142 1.00 184.67 ? 1   C   C "O2'" 1 
ATOM   5619 C "C1'" . C   C 2 1   ? 129.786 122.460 100.576 1.00 184.67 ? 1   C   C "C1'" 1 
ATOM   5620 N N1    . C   C 2 1   ? 130.675 123.034 99.535  1.00 184.67 ? 1   C   C N1    1 
ATOM   5621 C C2    . C   C 2 1   ? 130.135 123.285 98.268  1.00 184.67 ? 1   C   C C2    1 
ATOM   5622 O O2    . C   C 2 1   ? 128.948 123.007 98.046  1.00 184.67 ? 1   C   C O2    1 
ATOM   5623 N N3    . C   C 2 1   ? 130.913 123.817 97.294  1.00 184.67 ? 1   C   C N3    1 
ATOM   5624 C C4    . C   C 2 1   ? 132.189 124.107 97.555  1.00 184.67 ? 1   C   C C4    1 
ATOM   5625 N N4    . C   C 2 1   ? 132.922 124.629 96.567  1.00 184.67 ? 1   C   C N4    1 
ATOM   5626 C C5    . C   C 2 1   ? 132.770 123.867 98.835  1.00 184.67 ? 1   C   C C5    1 
ATOM   5627 C C6    . C   C 2 1   ? 131.986 123.338 99.785  1.00 184.67 ? 1   C   C C6    1 
ATOM   5628 P P     . G   C 2 2   ? 131.852 118.661 102.587 1.00 201.56 ? 2   G   C P     1 
ATOM   5629 O OP1   . G   C 2 2   ? 132.152 117.955 103.858 1.00 201.56 ? 2   G   C OP1   1 
ATOM   5630 O OP2   . G   C 2 2   ? 132.966 119.164 101.744 1.00 201.56 ? 2   G   C OP2   1 
ATOM   5631 O "O5'" . G   C 2 2   ? 130.949 117.702 101.690 1.00 201.56 ? 2   G   C "O5'" 1 
ATOM   5632 C "C5'" . G   C 2 2   ? 131.539 116.743 100.824 1.00 201.56 ? 2   G   C "C5'" 1 
ATOM   5633 C "C4'" . G   C 2 2   ? 130.788 116.652 99.520  1.00 201.56 ? 2   G   C "C4'" 1 
ATOM   5634 O "O4'" . G   C 2 2   ? 130.302 117.967 99.150  1.00 201.56 ? 2   G   C "O4'" 1 
ATOM   5635 C "C3'" . G   C 2 2   ? 131.599 116.200 98.314  1.00 201.56 ? 2   G   C "C3'" 1 
ATOM   5636 O "O3'" . G   C 2 2   ? 131.729 114.791 98.232  1.00 201.56 ? 2   G   C "O3'" 1 
ATOM   5637 C "C2'" . G   C 2 2   ? 130.834 116.808 97.147  1.00 201.56 ? 2   G   C "C2'" 1 
ATOM   5638 O "O2'" . G   C 2 2   ? 129.689 116.028 96.835  1.00 201.56 ? 2   G   C "O2'" 1 
ATOM   5639 C "C1'" . G   C 2 2   ? 130.363 118.130 97.750  1.00 201.56 ? 2   G   C "C1'" 1 
ATOM   5640 N N9    . G   C 2 2   ? 131.282 119.243 97.452  1.00 201.56 ? 2   G   C N9    1 
ATOM   5641 C C8    . G   C 2 2   ? 132.093 119.900 98.343  1.00 201.56 ? 2   G   C C8    1 
ATOM   5642 N N7    . G   C 2 2   ? 132.790 120.855 97.794  1.00 201.56 ? 2   G   C N7    1 
ATOM   5643 C C5    . G   C 2 2   ? 132.412 120.829 96.460  1.00 201.56 ? 2   G   C C5    1 
ATOM   5644 C C6    . G   C 2 2   ? 132.834 121.634 95.374  1.00 201.56 ? 2   G   C C6    1 
ATOM   5645 O O6    . G   C 2 2   ? 133.654 122.560 95.378  1.00 201.56 ? 2   G   C O6    1 
ATOM   5646 N N1    . G   C 2 2   ? 132.202 121.267 94.190  1.00 201.56 ? 2   G   C N1    1 
ATOM   5647 C C2    . G   C 2 2   ? 131.277 120.259 94.066  1.00 201.56 ? 2   G   C C2    1 
ATOM   5648 N N2    . G   C 2 2   ? 130.767 120.049 92.843  1.00 201.56 ? 2   G   C N2    1 
ATOM   5649 N N3    . G   C 2 2   ? 130.875 119.502 95.074  1.00 201.56 ? 2   G   C N3    1 
ATOM   5650 C C4    . G   C 2 2   ? 131.479 119.842 96.232  1.00 201.56 ? 2   G   C C4    1 
ATOM   5651 P P     . U   C 2 3   ? 132.969 114.136 97.447  1.00 213.14 ? 3   U   C P     1 
ATOM   5652 O OP1   . U   C 2 3   ? 132.905 112.664 97.635  1.00 213.14 ? 3   U   C OP1   1 
ATOM   5653 O OP2   . U   C 2 3   ? 134.198 114.872 97.838  1.00 213.14 ? 3   U   C OP2   1 
ATOM   5654 O "O5'" . U   C 2 3   ? 132.673 114.451 95.913  1.00 213.14 ? 3   U   C "O5'" 1 
ATOM   5655 C "C5'" . U   C 2 3   ? 131.558 113.874 95.246  1.00 213.14 ? 3   U   C "C5'" 1 
ATOM   5656 C "C4'" . U   C 2 3   ? 131.500 114.306 93.802  1.00 213.14 ? 3   U   C "C4'" 1 
ATOM   5657 O "O4'" . U   C 2 3   ? 131.242 115.732 93.723  1.00 213.14 ? 3   U   C "O4'" 1 
ATOM   5658 C "C3'" . U   C 2 3   ? 132.782 114.116 93.008  1.00 213.14 ? 3   U   C "C3'" 1 
ATOM   5659 O "O3'" . U   C 2 3   ? 132.941 112.790 92.536  1.00 213.14 ? 3   U   C "O3'" 1 
ATOM   5660 C "C2'" . U   C 2 3   ? 132.648 115.151 91.898  1.00 213.14 ? 3   U   C "C2'" 1 
ATOM   5661 O "O2'" . U   C 2 3   ? 131.790 114.676 90.870  1.00 213.14 ? 3   U   C "O2'" 1 
ATOM   5662 C "C1'" . U   C 2 3   ? 131.939 116.291 92.630  1.00 213.14 ? 3   U   C "C1'" 1 
ATOM   5663 N N1    . U   C 2 3   ? 132.884 117.306 93.149  1.00 213.14 ? 3   U   C N1    1 
ATOM   5664 C C2    . U   C 2 3   ? 133.403 118.246 92.275  1.00 213.14 ? 3   U   C C2    1 
ATOM   5665 O O2    . U   C 2 3   ? 133.125 118.273 91.088  1.00 213.14 ? 3   U   C O2    1 
ATOM   5666 N N3    . U   C 2 3   ? 134.266 119.155 92.842  1.00 213.14 ? 3   U   C N3    1 
ATOM   5667 C C4    . U   C 2 3   ? 134.646 119.210 94.171  1.00 213.14 ? 3   U   C C4    1 
ATOM   5668 O O4    . U   C 2 3   ? 135.425 120.080 94.559  1.00 213.14 ? 3   U   C O4    1 
ATOM   5669 C C5    . U   C 2 3   ? 134.063 118.209 95.006  1.00 213.14 ? 3   U   C C5    1 
ATOM   5670 C C6    . U   C 2 3   ? 133.222 117.317 94.480  1.00 213.14 ? 3   U   C C6    1 
ATOM   5671 P P     . G   C 2 4   ? 134.164 111.891 93.058  1.00 210.64 ? 4   G   C P     1 
ATOM   5672 O OP1   . G   C 2 4   ? 133.816 110.465 92.831  1.00 210.64 ? 4   G   C OP1   1 
ATOM   5673 O OP2   . G   C 2 4   ? 134.525 112.351 94.424  1.00 210.64 ? 4   G   C OP2   1 
ATOM   5674 O "O5'" . G   C 2 4   ? 135.360 112.268 92.078  1.00 210.64 ? 4   G   C "O5'" 1 
ATOM   5675 C "C5'" . G   C 2 4   ? 135.312 111.913 90.705  1.00 210.64 ? 4   G   C "C5'" 1 
ATOM   5676 C "C4'" . G   C 2 4   ? 136.464 112.515 89.942  1.00 210.64 ? 4   G   C "C4'" 1 
ATOM   5677 O "O4'" . G   C 2 4   ? 136.190 113.909 89.648  1.00 210.64 ? 4   G   C "O4'" 1 
ATOM   5678 C "C3'" . G   C 2 4   ? 137.797 112.550 90.671  1.00 210.64 ? 4   G   C "C3'" 1 
ATOM   5679 O "O3'" . G   C 2 4   ? 138.482 111.311 90.642  1.00 210.64 ? 4   G   C "O3'" 1 
ATOM   5680 C "C2'" . G   C 2 4   ? 138.532 113.676 89.957  1.00 210.64 ? 4   G   C "C2'" 1 
ATOM   5681 O "O2'" . G   C 2 4   ? 139.042 113.230 88.709  1.00 210.64 ? 4   G   C "O2'" 1 
ATOM   5682 C "C1'" . G   C 2 4   ? 137.390 114.654 89.690  1.00 210.64 ? 4   G   C "C1'" 1 
ATOM   5683 N N9    . G   C 2 4   ? 137.271 115.671 90.752  1.00 210.64 ? 4   G   C N9    1 
ATOM   5684 C C8    . G   C 2 4   ? 136.439 115.623 91.844  1.00 210.64 ? 4   G   C C8    1 
ATOM   5685 N N7    . G   C 2 4   ? 136.545 116.668 92.617  1.00 210.64 ? 4   G   C N7    1 
ATOM   5686 C C5    . G   C 2 4   ? 137.506 117.453 91.996  1.00 210.64 ? 4   G   C C5    1 
ATOM   5687 C C6    . G   C 2 4   ? 138.042 118.709 92.373  1.00 210.64 ? 4   G   C C6    1 
ATOM   5688 O O6    . G   C 2 4   ? 137.761 119.398 93.358  1.00 210.64 ? 4   G   C O6    1 
ATOM   5689 N N1    . G   C 2 4   ? 138.994 119.161 91.466  1.00 210.64 ? 4   G   C N1    1 
ATOM   5690 C C2    . G   C 2 4   ? 139.389 118.486 90.337  1.00 210.64 ? 4   G   C C2    1 
ATOM   5691 N N2    . G   C 2 4   ? 140.325 119.078 89.579  1.00 210.64 ? 4   G   C N2    1 
ATOM   5692 N N3    . G   C 2 4   ? 138.897 117.310 89.975  1.00 210.64 ? 4   G   C N3    1 
ATOM   5693 C C4    . G   C 2 4   ? 137.967 116.855 90.844  1.00 210.64 ? 4   G   C C4    1 
ATOM   5694 P P     . G   C 2 5   ? 139.168 110.740 91.979  1.00 205.43 ? 5   G   C P     1 
ATOM   5695 O OP1   . G   C 2 5   ? 139.779 109.425 91.656  1.00 205.43 ? 5   G   C OP1   1 
ATOM   5696 O OP2   . G   C 2 5   ? 138.179 110.839 93.083  1.00 205.43 ? 5   G   C OP2   1 
ATOM   5697 O "O5'" . G   C 2 5   ? 140.343 111.772 92.280  1.00 205.43 ? 5   G   C "O5'" 1 
ATOM   5698 C "C5'" . G   C 2 5   ? 141.356 112.019 91.317  1.00 205.43 ? 5   G   C "C5'" 1 
ATOM   5699 C "C4'" . G   C 2 5   ? 142.064 113.325 91.576  1.00 205.43 ? 5   G   C "C4'" 1 
ATOM   5700 O "O4'" . G   C 2 5   ? 141.103 114.416 91.609  1.00 205.43 ? 5   G   C "O4'" 1 
ATOM   5701 C "C3'" . G   C 2 5   ? 142.782 113.441 92.909  1.00 205.43 ? 5   G   C "C3'" 1 
ATOM   5702 O "O3'" . G   C 2 5   ? 144.028 112.770 92.942  1.00 205.43 ? 5   G   C "O3'" 1 
ATOM   5703 C "C2'" . G   C 2 5   ? 142.873 114.949 93.092  1.00 205.43 ? 5   G   C "C2'" 1 
ATOM   5704 O "O2'" . G   C 2 5   ? 143.875 115.497 92.249  1.00 205.43 ? 5   G   C "O2'" 1 
ATOM   5705 C "C1'" . G   C 2 5   ? 141.506 115.381 92.561  1.00 205.43 ? 5   G   C "C1'" 1 
ATOM   5706 N N9    . G   C 2 5   ? 140.512 115.407 93.649  1.00 205.43 ? 5   G   C N9    1 
ATOM   5707 C C8    . G   C 2 5   ? 139.616 114.419 93.979  1.00 205.43 ? 5   G   C C8    1 
ATOM   5708 N N7    . G   C 2 5   ? 138.878 114.720 95.012  1.00 205.43 ? 5   G   C N7    1 
ATOM   5709 C C5    . G   C 2 5   ? 139.319 115.979 95.394  1.00 205.43 ? 5   G   C C5    1 
ATOM   5710 C C6    . G   C 2 5   ? 138.891 116.820 96.455  1.00 205.43 ? 5   G   C C6    1 
ATOM   5711 O O6    . G   C 2 5   ? 138.009 116.613 97.297  1.00 205.43 ? 5   G   C O6    1 
ATOM   5712 N N1    . G   C 2 5   ? 139.609 118.009 96.483  1.00 205.43 ? 5   G   C N1    1 
ATOM   5713 C C2    . G   C 2 5   ? 140.607 118.349 95.605  1.00 205.43 ? 5   G   C C2    1 
ATOM   5714 N N2    . G   C 2 5   ? 141.178 119.544 95.800  1.00 205.43 ? 5   G   C N2    1 
ATOM   5715 N N3    . G   C 2 5   ? 141.018 117.578 94.611  1.00 205.43 ? 5   G   C N3    1 
ATOM   5716 C C4    . G   C 2 5   ? 140.333 116.415 94.567  1.00 205.43 ? 5   G   C C4    1 
ATOM   5717 P P     . U   C 2 6   ? 144.206 111.478 93.881  1.00 194.03 ? 6   U   C P     1 
ATOM   5718 O OP1   . U   C 2 6   ? 145.653 111.150 93.940  1.00 194.03 ? 6   U   C OP1   1 
ATOM   5719 O OP2   . U   C 2 6   ? 143.240 110.443 93.433  1.00 194.03 ? 6   U   C OP2   1 
ATOM   5720 O "O5'" . U   C 2 6   ? 143.748 111.987 95.321  1.00 194.03 ? 6   U   C "O5'" 1 
ATOM   5721 C "C5'" . U   C 2 6   ? 143.022 111.144 96.205  1.00 194.03 ? 6   U   C "C5'" 1 
ATOM   5722 C "C4'" . U   C 2 6   ? 143.437 111.368 97.638  1.00 194.03 ? 6   U   C "C4'" 1 
ATOM   5723 O "O4'" . U   C 2 6   ? 144.769 110.837 97.841  1.00 194.03 ? 6   U   C "O4'" 1 
ATOM   5724 C "C3'" . U   C 2 6   ? 143.534 112.823 98.075  1.00 194.03 ? 6   U   C "C3'" 1 
ATOM   5725 O "O3'" . U   C 2 6   ? 142.285 113.348 98.491  1.00 194.03 ? 6   U   C "O3'" 1 
ATOM   5726 C "C2'" . U   C 2 6   ? 144.564 112.782 99.198  1.00 194.03 ? 6   U   C "C2'" 1 
ATOM   5727 O "O2'" . U   C 2 6   ? 143.957 112.397 100.423 1.00 194.03 ? 6   U   C "O2'" 1 
ATOM   5728 C "C1'" . U   C 2 6   ? 145.488 111.652 98.740  1.00 194.03 ? 6   U   C "C1'" 1 
ATOM   5729 N N1    . U   C 2 6   ? 146.712 112.134 98.059  1.00 194.03 ? 6   U   C N1    1 
ATOM   5730 C C2    . U   C 2 6   ? 147.743 112.631 98.834  1.00 194.03 ? 6   U   C C2    1 
ATOM   5731 O O2    . U   C 2 6   ? 147.682 112.715 100.049 1.00 194.03 ? 6   U   C O2    1 
ATOM   5732 N N3    . U   C 2 6   ? 148.850 113.039 98.130  1.00 194.03 ? 6   U   C N3    1 
ATOM   5733 C C4    . U   C 2 6   ? 149.031 112.993 96.763  1.00 194.03 ? 6   U   C C4    1 
ATOM   5734 O O4    . U   C 2 6   ? 150.088 113.398 96.277  1.00 194.03 ? 6   U   C O4    1 
ATOM   5735 C C5    . U   C 2 6   ? 147.925 112.455 96.034  1.00 194.03 ? 6   U   C C5    1 
ATOM   5736 C C6    . U   C 2 6   ? 146.834 112.051 96.692  1.00 194.03 ? 6   U   C C6    1 
ATOM   5737 P P     . U   C 2 7   ? 141.314 114.088 97.446  1.00 197.58 ? 7   U   C P     1 
ATOM   5738 O OP1   . U   C 2 7   ? 140.130 113.219 97.229  1.00 197.58 ? 7   U   C OP1   1 
ATOM   5739 O OP2   . U   C 2 7   ? 142.130 114.524 96.285  1.00 197.58 ? 7   U   C OP2   1 
ATOM   5740 O "O5'" . U   C 2 7   ? 140.831 115.389 98.230  1.00 197.58 ? 7   U   C "O5'" 1 
ATOM   5741 C "C5'" . U   C 2 7   ? 140.256 115.289 99.525  1.00 197.58 ? 7   U   C "C5'" 1 
ATOM   5742 C "C4'" . U   C 2 7   ? 141.109 115.978 100.560 1.00 197.58 ? 7   U   C "C4'" 1 
ATOM   5743 O "O4'" . U   C 2 7   ? 142.462 115.456 100.496 1.00 197.58 ? 7   U   C "O4'" 1 
ATOM   5744 C "C3'" . U   C 2 7   ? 141.282 117.480 100.387 1.00 197.58 ? 7   U   C "C3'" 1 
ATOM   5745 O "O3'" . U   C 2 7   ? 140.194 118.225 100.907 1.00 197.58 ? 7   U   C "O3'" 1 
ATOM   5746 C "C2'" . U   C 2 7   ? 142.602 117.751 101.098 1.00 197.58 ? 7   U   C "C2'" 1 
ATOM   5747 O "O2'" . U   C 2 7   ? 142.413 117.808 102.505 1.00 197.58 ? 7   U   C "O2'" 1 
ATOM   5748 C "C1'" . U   C 2 7   ? 143.392 116.483 100.768 1.00 197.58 ? 7   U   C "C1'" 1 
ATOM   5749 N N1    . U   C 2 7   ? 144.270 116.653 99.586  1.00 197.58 ? 7   U   C N1    1 
ATOM   5750 C C2    . U   C 2 7   ? 145.545 117.139 99.798  1.00 197.58 ? 7   U   C C2    1 
ATOM   5751 O O2    . U   C 2 7   ? 145.964 117.430 100.905 1.00 197.58 ? 7   U   C O2    1 
ATOM   5752 N N3    . U   C 2 7   ? 146.312 117.271 98.666  1.00 197.58 ? 7   U   C N3    1 
ATOM   5753 C C4    . U   C 2 7   ? 145.943 116.973 97.369  1.00 197.58 ? 7   U   C C4    1 
ATOM   5754 O O4    . U   C 2 7   ? 146.747 117.148 96.452  1.00 197.58 ? 7   U   C O4    1 
ATOM   5755 C C5    . U   C 2 7   ? 144.610 116.476 97.231  1.00 197.58 ? 7   U   C C5    1 
ATOM   5756 C C6    . U   C 2 7   ? 143.843 116.337 98.317  1.00 197.58 ? 7   U   C C6    1 
ATOM   5757 P P     . G   C 2 8   ? 139.649 119.517 100.122 1.00 192.45 ? 8   G   C P     1 
ATOM   5758 O OP1   . G   C 2 8   ? 138.429 119.995 100.820 1.00 192.45 ? 8   G   C OP1   1 
ATOM   5759 O OP2   . G   C 2 8   ? 139.583 119.182 98.677  1.00 192.45 ? 8   G   C OP2   1 
ATOM   5760 O "O5'" . G   C 2 8   ? 140.793 120.606 100.329 1.00 192.45 ? 8   G   C "O5'" 1 
ATOM   5761 C "C5'" . G   C 2 8   ? 141.011 121.201 101.600 1.00 192.45 ? 8   G   C "C5'" 1 
ATOM   5762 C "C4'" . G   C 2 8   ? 142.159 122.181 101.569 1.00 192.45 ? 8   G   C "C4'" 1 
ATOM   5763 O "O4'" . G   C 2 8   ? 143.419 121.467 101.463 1.00 192.45 ? 8   G   C "O4'" 1 
ATOM   5764 C "C3'" . G   C 2 8   ? 142.183 123.147 100.394 1.00 192.45 ? 8   G   C "C3'" 1 
ATOM   5765 O "O3'" . G   C 2 8   ? 141.315 124.254 100.568 1.00 192.45 ? 8   G   C "O3'" 1 
ATOM   5766 C "C2'" . G   C 2 8   ? 143.653 123.532 100.312 1.00 192.45 ? 8   G   C "C2'" 1 
ATOM   5767 O "O2'" . G   C 2 8   ? 143.976 124.497 101.303 1.00 192.45 ? 8   G   C "O2'" 1 
ATOM   5768 C "C1'" . G   C 2 8   ? 144.331 122.213 100.683 1.00 192.45 ? 8   G   C "C1'" 1 
ATOM   5769 N N9    . G   C 2 8   ? 144.685 121.418 99.492  1.00 192.45 ? 8   G   C N9    1 
ATOM   5770 C C8    . G   C 2 8   ? 144.206 120.173 99.165  1.00 192.45 ? 8   G   C C8    1 
ATOM   5771 N N7    . G   C 2 8   ? 144.697 119.711 98.049  1.00 192.45 ? 8   G   C N7    1 
ATOM   5772 C C5    . G   C 2 8   ? 145.555 120.709 97.611  1.00 192.45 ? 8   G   C C5    1 
ATOM   5773 C C6    . G   C 2 8   ? 146.372 120.774 96.453  1.00 192.45 ? 8   G   C C6    1 
ATOM   5774 O O6    . G   C 2 8   ? 146.504 119.934 95.554  1.00 192.45 ? 8   G   C O6    1 
ATOM   5775 N N1    . G   C 2 8   ? 147.083 121.967 96.394  1.00 192.45 ? 8   G   C N1    1 
ATOM   5776 C C2    . G   C 2 8   ? 147.020 122.969 97.330  1.00 192.45 ? 8   G   C C2    1 
ATOM   5777 N N2    . G   C 2 8   ? 147.782 124.047 97.095  1.00 192.45 ? 8   G   C N2    1 
ATOM   5778 N N3    . G   C 2 8   ? 146.262 122.923 98.413  1.00 192.45 ? 8   G   C N3    1 
ATOM   5779 C C4    . G   C 2 8   ? 145.562 121.771 98.491  1.00 192.45 ? 8   G   C C4    1 
ATOM   5780 P P     . A   C 2 9   ? 140.699 125.003 99.287  1.00 195.44 ? 9   A   C P     1 
ATOM   5781 O OP1   . A   C 2 9   ? 139.573 125.854 99.750  1.00 195.44 ? 9   A   C OP1   1 
ATOM   5782 O OP2   . A   C 2 9   ? 140.457 123.984 98.235  1.00 195.44 ? 9   A   C OP2   1 
ATOM   5783 O "O5'" . A   C 2 9   ? 141.877 125.954 98.788  1.00 195.44 ? 9   A   C "O5'" 1 
ATOM   5784 C "C5'" . A   C 2 9   ? 141.797 126.617 97.535  1.00 195.44 ? 9   A   C "C5'" 1 
ATOM   5785 C "C4'" . A   C 2 9   ? 143.129 126.631 96.827  1.00 195.44 ? 9   A   C "C4'" 1 
ATOM   5786 O "O4'" . A   C 2 9   ? 143.873 125.433 97.166  1.00 195.44 ? 9   A   C "O4'" 1 
ATOM   5787 C "C3'" . A   C 2 9   ? 143.066 126.621 95.306  1.00 195.44 ? 9   A   C "C3'" 1 
ATOM   5788 O "O3'" . A   C 2 9   ? 142.878 127.914 94.755  1.00 195.44 ? 9   A   C "O3'" 1 
ATOM   5789 C "C2'" . A   C 2 9   ? 144.392 125.983 94.914  1.00 195.44 ? 9   A   C "C2'" 1 
ATOM   5790 O "O2'" . A   C 2 9   ? 145.444 126.935 94.976  1.00 195.44 ? 9   A   C "O2'" 1 
ATOM   5791 C "C1'" . A   C 2 9   ? 144.591 124.971 96.043  1.00 195.44 ? 9   A   C "C1'" 1 
ATOM   5792 N N9    . A   C 2 9   ? 144.089 123.626 95.701  1.00 195.44 ? 9   A   C N9    1 
ATOM   5793 C C8    . A   C 2 9   ? 143.223 122.878 96.458  1.00 195.44 ? 9   A   C C8    1 
ATOM   5794 N N7    . A   C 2 9   ? 142.939 121.710 95.943  1.00 195.44 ? 9   A   C N7    1 
ATOM   5795 C C5    . A   C 2 9   ? 143.670 121.679 94.766  1.00 195.44 ? 9   A   C C5    1 
ATOM   5796 C C6    . A   C 2 9   ? 143.793 120.700 93.765  1.00 195.44 ? 9   A   C C6    1 
ATOM   5797 N N6    . A   C 2 9   ? 143.155 119.526 93.797  1.00 195.44 ? 9   A   C N6    1 
ATOM   5798 N N1    . A   C 2 9   ? 144.602 120.973 92.718  1.00 195.44 ? 9   A   C N1    1 
ATOM   5799 C C2    . A   C 2 9   ? 145.238 122.151 92.692  1.00 195.44 ? 9   A   C C2    1 
ATOM   5800 N N3    . A   C 2 9   ? 145.202 123.149 93.572  1.00 195.44 ? 9   A   C N3    1 
ATOM   5801 C C4    . A   C 2 9   ? 144.391 122.850 94.603  1.00 195.44 ? 9   A   C C4    1 
ATOM   5802 P P     . C   C 2 10  ? 141.745 128.169 93.646  1.00 205.93 ? 10  C   C P     1 
ATOM   5803 O OP1   . C   C 2 10  ? 141.957 129.525 93.079  1.00 205.93 ? 10  C   C OP1   1 
ATOM   5804 O OP2   . C   C 2 10  ? 140.429 127.822 94.242  1.00 205.93 ? 10  C   C OP2   1 
ATOM   5805 O "O5'" . C   C 2 10  ? 142.069 127.105 92.505  1.00 205.93 ? 10  C   C "O5'" 1 
ATOM   5806 C "C5'" . C   C 2 10  ? 143.192 127.264 91.649  1.00 205.93 ? 10  C   C "C5'" 1 
ATOM   5807 C "C4'" . C   C 2 10  ? 143.268 126.151 90.635  1.00 205.93 ? 10  C   C "C4'" 1 
ATOM   5808 O "O4'" . C   C 2 10  ? 143.566 124.900 91.306  1.00 205.93 ? 10  C   C "O4'" 1 
ATOM   5809 C "C3'" . C   C 2 10  ? 141.984 125.870 89.869  1.00 205.93 ? 10  C   C "C3'" 1 
ATOM   5810 O "O3'" . C   C 2 10  ? 141.804 126.743 88.768  1.00 205.93 ? 10  C   C "O3'" 1 
ATOM   5811 C "C2'" . C   C 2 10  ? 142.140 124.408 89.469  1.00 205.93 ? 10  C   C "C2'" 1 
ATOM   5812 O "O2'" . C   C 2 10  ? 142.980 124.287 88.331  1.00 205.93 ? 10  C   C "O2'" 1 
ATOM   5813 C "C1'" . C   C 2 10  ? 142.881 123.837 90.679  1.00 205.93 ? 10  C   C "C1'" 1 
ATOM   5814 N N1    . C   C 2 10  ? 141.968 123.221 91.671  1.00 205.93 ? 10  C   C N1    1 
ATOM   5815 C C2    . C   C 2 10  ? 141.458 121.937 91.448  1.00 205.93 ? 10  C   C C2    1 
ATOM   5816 O O2    . C   C 2 10  ? 141.768 121.331 90.411  1.00 205.93 ? 10  C   C O2    1 
ATOM   5817 N N3    . C   C 2 10  ? 140.633 121.387 92.370  1.00 205.93 ? 10  C   C N3    1 
ATOM   5818 C C4    . C   C 2 10  ? 140.321 122.066 93.476  1.00 205.93 ? 10  C   C C4    1 
ATOM   5819 N N4    . C   C 2 10  ? 139.505 121.489 94.360  1.00 205.93 ? 10  C   C N4    1 
ATOM   5820 C C5    . C   C 2 10  ? 140.829 123.371 93.731  1.00 205.93 ? 10  C   C C5    1 
ATOM   5821 C C6    . C   C 2 10  ? 141.643 123.901 92.812  1.00 205.93 ? 10  C   C C6    1 
ATOM   5822 P P     . A   C 2 11  ? 140.383 127.449 88.515  1.00 213.02 ? 11  A   C P     1 
ATOM   5823 O OP1   . A   C 2 11  ? 140.634 128.852 88.099  1.00 213.02 ? 11  A   C OP1   1 
ATOM   5824 O OP2   . A   C 2 11  ? 139.520 127.177 89.693  1.00 213.02 ? 11  A   C OP2   1 
ATOM   5825 O "O5'" . A   C 2 11  ? 139.779 126.663 87.268  1.00 213.02 ? 11  A   C "O5'" 1 
ATOM   5826 C "C5'" . A   C 2 11  ? 138.525 127.034 86.714  1.00 213.02 ? 11  A   C "C5'" 1 
ATOM   5827 C "C4'" . A   C 2 11  ? 137.749 125.828 86.247  1.00 213.02 ? 11  A   C "C4'" 1 
ATOM   5828 O "O4'" . A   C 2 11  ? 138.380 124.618 86.737  1.00 213.02 ? 11  A   C "O4'" 1 
ATOM   5829 C "C3'" . A   C 2 11  ? 136.316 125.731 86.749  1.00 213.02 ? 11  A   C "C3'" 1 
ATOM   5830 O "O3'" . A   C 2 11  ? 135.413 126.511 85.984  1.00 213.02 ? 11  A   C "O3'" 1 
ATOM   5831 C "C2'" . A   C 2 11  ? 136.037 124.236 86.685  1.00 213.02 ? 11  A   C "C2'" 1 
ATOM   5832 O "O2'" . A   C 2 11  ? 135.735 123.838 85.356  1.00 213.02 ? 11  A   C "O2'" 1 
ATOM   5833 C "C1'" . A   C 2 11  ? 137.399 123.657 87.063  1.00 213.02 ? 11  A   C "C1'" 1 
ATOM   5834 N N9    . A   C 2 11  ? 137.504 123.362 88.504  1.00 213.02 ? 11  A   C N9    1 
ATOM   5835 C C8    . A   C 2 11  ? 138.274 124.033 89.422  1.00 213.02 ? 11  A   C C8    1 
ATOM   5836 N N7    . A   C 2 11  ? 138.188 123.552 90.636  1.00 213.02 ? 11  A   C N7    1 
ATOM   5837 C C5    . A   C 2 11  ? 137.305 122.490 90.506  1.00 213.02 ? 11  A   C C5    1 
ATOM   5838 C C6    . A   C 2 11  ? 136.801 121.574 91.440  1.00 213.02 ? 11  A   C C6    1 
ATOM   5839 N N6    . A   C 2 11  ? 137.136 121.598 92.729  1.00 213.02 ? 11  A   C N6    1 
ATOM   5840 N N1    . A   C 2 11  ? 135.937 120.630 91.007  1.00 213.02 ? 11  A   C N1    1 
ATOM   5841 C C2    . A   C 2 11  ? 135.608 120.619 89.708  1.00 213.02 ? 11  A   C C2    1 
ATOM   5842 N N3    . A   C 2 11  ? 136.017 121.430 88.730  1.00 213.02 ? 11  A   C N3    1 
ATOM   5843 C C4    . A   C 2 11  ? 136.875 122.355 89.199  1.00 213.02 ? 11  A   C C4    1 
ATOM   5844 P P     . C   C 2 12  ? 134.128 127.176 86.682  1.00 206.34 ? 12  C   C P     1 
ATOM   5845 O OP1   . C   C 2 12  ? 133.464 128.051 85.683  1.00 206.34 ? 12  C   C OP1   1 
ATOM   5846 O OP2   . C   C 2 12  ? 134.555 127.743 87.986  1.00 206.34 ? 12  C   C OP2   1 
ATOM   5847 O "O5'" . C   C 2 12  ? 133.167 125.940 86.972  1.00 206.34 ? 12  C   C "O5'" 1 
ATOM   5848 C "C5'" . C   C 2 12  ? 132.675 125.133 85.912  1.00 206.34 ? 12  C   C "C5'" 1 
ATOM   5849 C "C4'" . C   C 2 12  ? 131.915 123.942 86.436  1.00 206.34 ? 12  C   C "C4'" 1 
ATOM   5850 O "O4'" . C   C 2 12  ? 132.823 123.040 87.120  1.00 206.34 ? 12  C   C "O4'" 1 
ATOM   5851 C "C3'" . C   C 2 12  ? 130.845 124.243 87.473  1.00 206.34 ? 12  C   C "C3'" 1 
ATOM   5852 O "O3'" . C   C 2 12  ? 129.634 124.705 86.901  1.00 206.34 ? 12  C   C "O3'" 1 
ATOM   5853 C "C2'" . C   C 2 12  ? 130.715 122.916 88.208  1.00 206.34 ? 12  C   C "C2'" 1 
ATOM   5854 O "O2'" . C   C 2 12  ? 129.938 121.998 87.453  1.00 206.34 ? 12  C   C "O2'" 1 
ATOM   5855 C "C1'" . C   C 2 12  ? 132.166 122.431 88.213  1.00 206.34 ? 12  C   C "C1'" 1 
ATOM   5856 N N1    . C   C 2 12  ? 132.875 122.803 89.459  1.00 206.34 ? 12  C   C N1    1 
ATOM   5857 C C2    . C   C 2 12  ? 132.683 122.025 90.606  1.00 206.34 ? 12  C   C C2    1 
ATOM   5858 O O2    . C   C 2 12  ? 131.924 121.047 90.551  1.00 206.34 ? 12  C   C O2    1 
ATOM   5859 N N3    . C   C 2 12  ? 133.327 122.356 91.749  1.00 206.34 ? 12  C   C N3    1 
ATOM   5860 C C4    . C   C 2 12  ? 134.137 123.416 91.773  1.00 206.34 ? 12  C   C C4    1 
ATOM   5861 N N4    . C   C 2 12  ? 134.754 123.709 92.920  1.00 206.34 ? 12  C   C N4    1 
ATOM   5862 C C5    . C   C 2 12  ? 134.353 124.225 90.621  1.00 206.34 ? 12  C   C C5    1 
ATOM   5863 C C6    . C   C 2 12  ? 133.710 123.885 89.497  1.00 206.34 ? 12  C   C C6    1 
ATOM   5864 P P     . G   C 2 13  ? 129.327 126.281 86.828  1.00 188.37 ? 13  G   C P     1 
ATOM   5865 O OP1   . G   C 2 13  ? 128.822 126.586 85.465  1.00 188.37 ? 13  G   C OP1   1 
ATOM   5866 O OP2   . G   C 2 13  ? 130.507 127.010 87.356  1.00 188.37 ? 13  G   C OP2   1 
ATOM   5867 O "O5'" . G   C 2 13  ? 128.131 126.493 87.857  1.00 188.37 ? 13  G   C "O5'" 1 
ATOM   5868 C "C5'" . G   C 2 13  ? 126.827 126.013 87.567  1.00 188.37 ? 13  G   C "C5'" 1 
ATOM   5869 C "C4'" . G   C 2 13  ? 126.167 125.441 88.795  1.00 188.37 ? 13  G   C "C4'" 1 
ATOM   5870 O "O4'" . G   C 2 13  ? 126.927 124.300 89.270  1.00 188.37 ? 13  G   C "O4'" 1 
ATOM   5871 C "C3'" . G   C 2 13  ? 126.092 126.361 90.004  1.00 188.37 ? 13  G   C "C3'" 1 
ATOM   5872 O "O3'" . G   C 2 13  ? 125.016 127.281 89.939  1.00 188.37 ? 13  G   C "O3'" 1 
ATOM   5873 C "C2'" . G   C 2 13  ? 125.979 125.378 91.159  1.00 188.37 ? 13  G   C "C2'" 1 
ATOM   5874 O "O2'" . G   C 2 13  ? 124.653 124.882 91.269  1.00 188.37 ? 13  G   C "O2'" 1 
ATOM   5875 C "C1'" . G   C 2 13  ? 126.879 124.243 90.681  1.00 188.37 ? 13  G   C "C1'" 1 
ATOM   5876 N N9    . G   C 2 13  ? 128.253 124.362 91.205  1.00 188.37 ? 13  G   C N9    1 
ATOM   5877 C C8    . G   C 2 13  ? 129.326 124.949 90.580  1.00 188.37 ? 13  G   C C8    1 
ATOM   5878 N N7    . G   C 2 13  ? 130.422 124.897 91.286  1.00 188.37 ? 13  G   C N7    1 
ATOM   5879 C C5    . G   C 2 13  ? 130.049 124.235 92.448  1.00 188.37 ? 13  G   C C5    1 
ATOM   5880 C C6    . G   C 2 13  ? 130.813 123.883 93.588  1.00 188.37 ? 13  G   C C6    1 
ATOM   5881 O O6    . G   C 2 13  ? 132.007 124.093 93.821  1.00 188.37 ? 13  G   C O6    1 
ATOM   5882 N N1    . G   C 2 13  ? 130.047 123.225 94.544  1.00 188.37 ? 13  G   C N1    1 
ATOM   5883 C C2    . G   C 2 13  ? 128.715 122.927 94.408  1.00 188.37 ? 13  G   C C2    1 
ATOM   5884 N N2    . G   C 2 13  ? 128.173 122.289 95.454  1.00 188.37 ? 13  G   C N2    1 
ATOM   5885 N N3    . G   C 2 13  ? 127.984 123.251 93.352  1.00 188.37 ? 13  G   C N3    1 
ATOM   5886 C C4    . G   C 2 13  ? 128.712 123.899 92.416  1.00 188.37 ? 13  G   C C4    1 
ATOM   5887 P P     . C   C 2 14  ? 125.106 128.685 90.717  1.00 173.66 ? 14  C   C P     1 
ATOM   5888 O OP1   . C   C 2 14  ? 123.913 129.489 90.351  1.00 173.66 ? 14  C   C OP1   1 
ATOM   5889 O OP2   . C   C 2 14  ? 126.464 129.242 90.496  1.00 173.66 ? 14  C   C OP2   1 
ATOM   5890 O "O5'" . C   C 2 14  ? 124.982 128.290 92.257  1.00 173.66 ? 14  C   C "O5'" 1 
ATOM   5891 C "C5'" . C   C 2 14  ? 123.781 127.739 92.778  1.00 173.66 ? 14  C   C "C5'" 1 
ATOM   5892 C "C4'" . C   C 2 14  ? 124.013 127.055 94.103  1.00 173.66 ? 14  C   C "C4'" 1 
ATOM   5893 O "O4'" . C   C 2 14  ? 125.061 126.061 93.965  1.00 173.66 ? 14  C   C "O4'" 1 
ATOM   5894 C "C3'" . C   C 2 14  ? 124.496 127.942 95.239  1.00 173.66 ? 14  C   C "C3'" 1 
ATOM   5895 O "O3'" . C   C 2 14  ? 123.446 128.658 95.865  1.00 173.66 ? 14  C   C "O3'" 1 
ATOM   5896 C "C2'" . C   C 2 14  ? 125.196 126.951 96.160  1.00 173.66 ? 14  C   C "C2'" 1 
ATOM   5897 O "O2'" . C   C 2 14  ? 124.248 126.224 96.927  1.00 173.66 ? 14  C   C "O2'" 1 
ATOM   5898 C "C1'" . C   C 2 14  ? 125.826 125.996 95.149  1.00 173.66 ? 14  C   C "C1'" 1 
ATOM   5899 N N1    . C   C 2 14  ? 127.228 126.360 94.835  1.00 173.66 ? 14  C   C N1    1 
ATOM   5900 C C2    . C   C 2 14  ? 128.238 125.880 95.672  1.00 173.66 ? 14  C   C C2    1 
ATOM   5901 O O2    . C   C 2 14  ? 127.924 125.173 96.639  1.00 173.66 ? 14  C   C O2    1 
ATOM   5902 N N3    . C   C 2 14  ? 129.527 126.197 95.411  1.00 173.66 ? 14  C   C N3    1 
ATOM   5903 C C4    . C   C 2 14  ? 129.825 126.962 94.361  1.00 173.66 ? 14  C   C C4    1 
ATOM   5904 N N4    . C   C 2 14  ? 131.110 127.249 94.141  1.00 173.66 ? 14  C   C N4    1 
ATOM   5905 C C5    . C   C 2 14  ? 128.818 127.466 93.488  1.00 173.66 ? 14  C   C C5    1 
ATOM   5906 C C6    . C   C 2 14  ? 127.547 127.144 93.761  1.00 173.66 ? 14  C   C C6    1 
ATOM   5907 P P     . A   C 2 15  ? 123.764 130.005 96.680  1.00 148.73 ? 15  A   C P     1 
ATOM   5908 O OP1   . A   C 2 15  ? 122.473 130.661 97.009  1.00 148.73 ? 15  A   C OP1   1 
ATOM   5909 O OP2   . A   C 2 15  ? 124.804 130.760 95.936  1.00 148.73 ? 15  A   C OP2   1 
ATOM   5910 O "O5'" . A   C 2 15  ? 124.412 129.487 98.039  1.00 148.73 ? 15  A   C "O5'" 1 
ATOM   5911 C "C5'" . A   C 2 15  ? 123.681 128.648 98.921  1.00 148.73 ? 15  A   C "C5'" 1 
ATOM   5912 C "C4'" . A   C 2 15  ? 124.449 128.390 100.191 1.00 148.73 ? 15  A   C "C4'" 1 
ATOM   5913 O "O4'" . A   C 2 15  ? 125.439 127.351 99.979  1.00 148.73 ? 15  A   C "O4'" 1 
ATOM   5914 C "C3'" . A   C 2 15  ? 125.254 129.563 100.719 1.00 148.73 ? 15  A   C "C3'" 1 
ATOM   5915 O "O3'" . A   C 2 15  ? 124.457 130.492 101.430 1.00 148.73 ? 15  A   C "O3'" 1 
ATOM   5916 C "C2'" . A   C 2 15  ? 126.316 128.882 101.572 1.00 148.73 ? 15  A   C "C2'" 1 
ATOM   5917 O "O2'" . A   C 2 15  ? 125.782 128.509 102.834 1.00 148.73 ? 15  A   C "O2'" 1 
ATOM   5918 C "C1'" . A   C 2 15  ? 126.584 127.609 100.766 1.00 148.73 ? 15  A   C "C1'" 1 
ATOM   5919 N N9    . A   C 2 15  ? 127.751 127.735 99.870  1.00 148.73 ? 15  A   C N9    1 
ATOM   5920 C C8    . A   C 2 15  ? 127.738 127.644 98.501  1.00 148.73 ? 15  A   C C8    1 
ATOM   5921 N N7    . A   C 2 15  ? 128.915 127.782 97.948  1.00 148.73 ? 15  A   C N7    1 
ATOM   5922 C C5    . A   C 2 15  ? 129.767 127.970 99.024  1.00 148.73 ? 15  A   C C5    1 
ATOM   5923 C C6    . A   C 2 15  ? 131.154 128.176 99.091  1.00 148.73 ? 15  A   C C6    1 
ATOM   5924 N N6    . A   C 2 15  ? 131.934 128.224 98.011  1.00 148.73 ? 15  A   C N6    1 
ATOM   5925 N N1    . A   C 2 15  ? 131.715 128.332 100.309 1.00 148.73 ? 15  A   C N1    1 
ATOM   5926 C C2    . A   C 2 15  ? 130.917 128.278 101.385 1.00 148.73 ? 15  A   C C2    1 
ATOM   5927 N N3    . A   C 2 15  ? 129.597 128.093 101.448 1.00 148.73 ? 15  A   C N3    1 
ATOM   5928 C C4    . A   C 2 15  ? 129.070 127.940 100.218 1.00 148.73 ? 15  A   C C4    1 
ATOM   5929 P P     . G   C 2 16  ? 124.599 132.065 101.138 1.00 140.31 ? 16  G   C P     1 
ATOM   5930 O OP1   . G   C 2 16  ? 123.319 132.722 101.505 1.00 140.31 ? 16  G   C OP1   1 
ATOM   5931 O OP2   . G   C 2 16  ? 125.145 132.230 99.767  1.00 140.31 ? 16  G   C OP2   1 
ATOM   5932 O "O5'" . G   C 2 16  ? 125.711 132.536 102.173 1.00 140.31 ? 16  G   C "O5'" 1 
ATOM   5933 C "C5'" . G   C 2 16  ? 125.669 132.102 103.523 1.00 140.31 ? 16  G   C "C5'" 1 
ATOM   5934 C "C4'" . G   C 2 16  ? 127.050 132.033 104.121 1.00 140.31 ? 16  G   C "C4'" 1 
ATOM   5935 O "O4'" . G   C 2 16  ? 127.812 130.973 103.489 1.00 140.31 ? 16  G   C "O4'" 1 
ATOM   5936 C "C3'" . G   C 2 16  ? 127.912 133.269 103.933 1.00 140.31 ? 16  G   C "C3'" 1 
ATOM   5937 O "O3'" . G   C 2 16  ? 127.611 134.291 104.866 1.00 140.31 ? 16  G   C "O3'" 1 
ATOM   5938 C "C2'" . G   C 2 16  ? 129.324 132.713 104.066 1.00 140.31 ? 16  G   C "C2'" 1 
ATOM   5939 O "O2'" . G   C 2 16  ? 129.663 132.526 105.432 1.00 140.31 ? 16  G   C "O2'" 1 
ATOM   5940 C "C1'" . G   C 2 16  ? 129.173 131.338 103.412 1.00 140.31 ? 16  G   C "C1'" 1 
ATOM   5941 N N9    . G   C 2 16  ? 129.588 131.336 101.995 1.00 140.31 ? 16  G   C N9    1 
ATOM   5942 C C8    . G   C 2 16  ? 128.794 131.129 100.893 1.00 140.31 ? 16  G   C C8    1 
ATOM   5943 N N7    . G   C 2 16  ? 129.451 131.177 99.766  1.00 140.31 ? 16  G   C N7    1 
ATOM   5944 C C5    . G   C 2 16  ? 130.762 131.431 100.144 1.00 140.31 ? 16  G   C C5    1 
ATOM   5945 C C6    . G   C 2 16  ? 131.933 131.591 99.360  1.00 140.31 ? 16  G   C C6    1 
ATOM   5946 O O6    . G   C 2 16  ? 132.049 131.539 98.130  1.00 140.31 ? 16  G   C O6    1 
ATOM   5947 N N1    . G   C 2 16  ? 133.051 131.835 100.151 1.00 140.31 ? 16  G   C N1    1 
ATOM   5948 C C2    . G   C 2 16  ? 133.043 131.914 101.523 1.00 140.31 ? 16  G   C C2    1 
ATOM   5949 N N2    . G   C 2 16  ? 134.213 132.155 102.130 1.00 140.31 ? 16  G   C N2    1 
ATOM   5950 N N3    . G   C 2 16  ? 131.959 131.762 102.263 1.00 140.31 ? 16  G   C N3    1 
ATOM   5951 C C4    . G   C 2 16  ? 130.862 131.529 101.515 1.00 140.31 ? 16  G   C C4    1 
ATOM   5952 P P     . A   C 2 17  ? 127.736 135.834 104.442 1.00 133.65 ? 17  A   C P     1 
ATOM   5953 O OP1   . A   C 2 17  ? 126.997 136.648 105.440 1.00 133.65 ? 17  A   C OP1   1 
ATOM   5954 O OP2   . A   C 2 17  ? 127.388 135.945 103.002 1.00 133.65 ? 17  A   C OP2   1 
ATOM   5955 O "O5'" . A   C 2 17  ? 129.289 136.145 104.601 1.00 133.65 ? 17  A   C "O5'" 1 
ATOM   5956 C "C5'" . A   C 2 17  ? 129.968 135.851 105.812 1.00 133.65 ? 17  A   C "C5'" 1 
ATOM   5957 C "C4'" . A   C 2 17  ? 131.462 135.849 105.618 1.00 133.65 ? 17  A   C "C4'" 1 
ATOM   5958 O "O4'" . A   C 2 17  ? 131.847 134.740 104.766 1.00 133.65 ? 17  A   C "O4'" 1 
ATOM   5959 C "C3'" . A   C 2 17  ? 132.037 137.070 104.920 1.00 133.65 ? 17  A   C "C3'" 1 
ATOM   5960 O "O3'" . A   C 2 17  ? 132.216 138.167 105.798 1.00 133.65 ? 17  A   C "O3'" 1 
ATOM   5961 C "C2'" . A   C 2 17  ? 133.337 136.538 104.331 1.00 133.65 ? 17  A   C "C2'" 1 
ATOM   5962 O "O2'" . A   C 2 17  ? 134.348 136.471 105.326 1.00 133.65 ? 17  A   C "O2'" 1 
ATOM   5963 C "C1'" . A   C 2 17  ? 132.939 135.112 103.952 1.00 133.65 ? 17  A   C "C1'" 1 
ATOM   5964 N N9    . A   C 2 17  ? 132.529 135.000 102.540 1.00 133.65 ? 17  A   C N9    1 
ATOM   5965 C C8    . A   C 2 17  ? 131.287 134.671 102.060 1.00 133.65 ? 17  A   C C8    1 
ATOM   5966 N N7    . A   C 2 17  ? 131.213 134.635 100.753 1.00 133.65 ? 17  A   C N7    1 
ATOM   5967 C C5    . A   C 2 17  ? 132.495 134.968 100.343 1.00 133.65 ? 17  A   C C5    1 
ATOM   5968 C C6    . A   C 2 17  ? 133.069 135.111 99.068  1.00 133.65 ? 17  A   C C6    1 
ATOM   5969 N N6    . A   C 2 17  ? 132.394 134.925 97.933  1.00 133.65 ? 17  A   C N6    1 
ATOM   5970 N N1    . A   C 2 17  ? 134.373 135.455 98.996  1.00 133.65 ? 17  A   C N1    1 
ATOM   5971 C C2    . A   C 2 17  ? 135.044 135.643 100.140 1.00 133.65 ? 17  A   C C2    1 
ATOM   5972 N N3    . A   C 2 17  ? 134.616 135.535 101.397 1.00 133.65 ? 17  A   C N3    1 
ATOM   5973 C C4    . A   C 2 17  ? 133.318 135.192 101.431 1.00 133.65 ? 17  A   C C4    1 
ATOM   5974 P P     . C   C 2 18  ? 131.991 139.667 105.272 1.00 135.16 ? 18  C   C P     1 
ATOM   5975 O OP1   . C   C 2 18  ? 132.032 140.573 106.448 1.00 135.16 ? 18  C   C OP1   1 
ATOM   5976 O OP2   . C   C 2 18  ? 130.801 139.672 104.385 1.00 135.16 ? 18  C   C OP2   1 
ATOM   5977 O "O5'" . C   C 2 18  ? 133.279 139.956 104.382 1.00 135.16 ? 18  C   C "O5'" 1 
ATOM   5978 C "C5'" . C   C 2 18  ? 134.581 139.878 104.943 1.00 135.16 ? 18  C   C "C5'" 1 
ATOM   5979 C "C4'" . C   C 2 18  ? 135.649 140.072 103.897 1.00 135.16 ? 18  C   C "C4'" 1 
ATOM   5980 O "O4'" . C   C 2 18  ? 135.690 138.925 103.006 1.00 135.16 ? 18  C   C "O4'" 1 
ATOM   5981 C "C3'" . C   C 2 18  ? 135.457 141.254 102.962 1.00 135.16 ? 18  C   C "C3'" 1 
ATOM   5982 O "O3'" . C   C 2 18  ? 135.849 142.489 103.534 1.00 135.16 ? 18  C   C "O3'" 1 
ATOM   5983 C "C2'" . C   C 2 18  ? 136.285 140.851 101.752 1.00 135.16 ? 18  C   C "C2'" 1 
ATOM   5984 O "O2'" . C   C 2 18  ? 137.668 141.055 102.001 1.00 135.16 ? 18  C   C "O2'" 1 
ATOM   5985 C "C1'" . C   C 2 18  ? 136.020 139.344 101.698 1.00 135.16 ? 18  C   C "C1'" 1 
ATOM   5986 N N1    . C   C 2 18  ? 134.888 139.018 100.800 1.00 135.16 ? 18  C   C N1    1 
ATOM   5987 C C2    . C   C 2 18  ? 135.010 139.223 99.420  1.00 135.16 ? 18  C   C C2    1 
ATOM   5988 O O2    . C   C 2 18  ? 136.064 139.684 98.958  1.00 135.16 ? 18  C   C O2    1 
ATOM   5989 N N3    . C   C 2 18  ? 133.966 138.927 98.612  1.00 135.16 ? 18  C   C N3    1 
ATOM   5990 C C4    . C   C 2 18  ? 132.837 138.443 99.130  1.00 135.16 ? 18  C   C C4    1 
ATOM   5991 N N4    . C   C 2 18  ? 131.830 138.164 98.300  1.00 135.16 ? 18  C   C N4    1 
ATOM   5992 C C5    . C   C 2 18  ? 132.688 138.222 100.528 1.00 135.16 ? 18  C   C C5    1 
ATOM   5993 C C6    . C   C 2 18  ? 133.726 138.519 101.317 1.00 135.16 ? 18  C   C C6    1 
ATOM   5994 P P     . C   C 2 19  ? 135.012 143.823 103.217 1.00 132.55 ? 19  C   C P     1 
ATOM   5995 O OP1   . C   C 2 19  ? 135.525 144.907 104.093 1.00 132.55 ? 19  C   C OP1   1 
ATOM   5996 O OP2   . C   C 2 19  ? 133.570 143.476 103.249 1.00 132.55 ? 19  C   C OP2   1 
ATOM   5997 O "O5'" . C   C 2 19  ? 135.402 144.177 101.713 1.00 132.55 ? 19  C   C "O5'" 1 
ATOM   5998 C "C5'" . C   C 2 19  ? 136.728 144.554 101.375 1.00 132.55 ? 19  C   C "C5'" 1 
ATOM   5999 C "C4'" . C   C 2 19  ? 136.882 144.788 99.892  1.00 132.55 ? 19  C   C "C4'" 1 
ATOM   6000 O "O4'" . C   C 2 19  ? 136.648 143.551 99.168  1.00 132.55 ? 19  C   C "O4'" 1 
ATOM   6001 C "C3'" . C   C 2 19  ? 135.909 145.773 99.264  1.00 132.55 ? 19  C   C "C3'" 1 
ATOM   6002 O "O3'" . C   C 2 19  ? 136.285 147.126 99.452  1.00 132.55 ? 19  C   C "O3'" 1 
ATOM   6003 C "C2'" . C   C 2 19  ? 135.906 145.348 97.804  1.00 132.55 ? 19  C   C "C2'" 1 
ATOM   6004 O "O2'" . C   C 2 19  ? 137.062 145.836 97.139  1.00 132.55 ? 19  C   C "O2'" 1 
ATOM   6005 C "C1'" . C   C 2 19  ? 136.027 143.828 97.929  1.00 132.55 ? 19  C   C "C1'" 1 
ATOM   6006 N N1    . C   C 2 19  ? 134.710 143.147 97.899  1.00 132.55 ? 19  C   C N1    1 
ATOM   6007 C C2    . C   C 2 19  ? 133.876 143.239 96.774  1.00 132.55 ? 19  C   C C2    1 
ATOM   6008 O O2    . C   C 2 19  ? 134.244 143.917 95.803  1.00 132.55 ? 19  C   C O2    1 
ATOM   6009 N N3    . C   C 2 19  ? 132.677 142.606 96.782  1.00 132.55 ? 19  C   C N3    1 
ATOM   6010 C C4    . C   C 2 19  ? 132.306 141.887 97.839  1.00 132.55 ? 19  C   C C4    1 
ATOM   6011 N N4    . C   C 2 19  ? 131.122 141.270 97.812  1.00 132.55 ? 19  C   C N4    1 
ATOM   6012 C C5    . C   C 2 19  ? 133.136 141.773 98.987  1.00 132.55 ? 19  C   C C5    1 
ATOM   6013 C C6    . C   C 2 19  ? 134.317 142.400 98.971  1.00 132.55 ? 19  C   C C6    1 
ATOM   6014 P P     . U   C 2 20  ? 135.180 148.292 99.380  1.00 136.62 ? 20  U   C P     1 
ATOM   6015 O OP1   . U   C 2 20  ? 135.845 149.574 99.728  1.00 136.62 ? 20  U   C OP1   1 
ATOM   6016 O OP2   . U   C 2 20  ? 133.996 147.846 100.156 1.00 136.62 ? 20  U   C OP2   1 
ATOM   6017 O "O5'" . U   C 2 20  ? 134.765 148.354 97.842  1.00 136.62 ? 20  U   C "O5'" 1 
ATOM   6018 C "C5'" . U   C 2 20  ? 135.614 148.960 96.877  1.00 136.62 ? 20  U   C "C5'" 1 
ATOM   6019 C "C4'" . U   C 2 20  ? 134.883 149.239 95.586  1.00 136.62 ? 20  U   C "C4'" 1 
ATOM   6020 O "O4'" . U   C 2 20  ? 134.530 147.990 94.936  1.00 136.62 ? 20  U   C "O4'" 1 
ATOM   6021 C "C3'" . U   C 2 20  ? 133.559 149.979 95.715  1.00 136.62 ? 20  U   C "C3'" 1 
ATOM   6022 O "O3'" . U   C 2 20  ? 133.722 151.381 95.839  1.00 136.62 ? 20  U   C "O3'" 1 
ATOM   6023 C "C2'" . U   C 2 20  ? 132.820 149.566 94.449  1.00 136.62 ? 20  U   C "C2'" 1 
ATOM   6024 O "O2'" . U   C 2 20  ? 133.281 150.314 93.334  1.00 136.62 ? 20  U   C "O2'" 1 
ATOM   6025 C "C1'" . U   C 2 20  ? 133.283 148.119 94.283  1.00 136.62 ? 20  U   C "C1'" 1 
ATOM   6026 N N1    . U   C 2 20  ? 132.341 147.151 94.890  1.00 136.62 ? 20  U   C N1    1 
ATOM   6027 C C2    . U   C 2 20  ? 131.120 146.895 94.286  1.00 136.62 ? 20  U   C C2    1 
ATOM   6028 O O2    . U   C 2 20  ? 130.748 147.450 93.266  1.00 136.62 ? 20  U   C O2    1 
ATOM   6029 N N3    . U   C 2 20  ? 130.335 145.972 94.944  1.00 136.62 ? 20  U   C N3    1 
ATOM   6030 C C4    . U   C 2 20  ? 130.641 145.296 96.106  1.00 136.62 ? 20  U   C C4    1 
ATOM   6031 O O4    . U   C 2 20  ? 129.852 144.488 96.597  1.00 136.62 ? 20  U   C O4    1 
ATOM   6032 C C5    . U   C 2 20  ? 131.915 145.621 96.652  1.00 136.62 ? 20  U   C C5    1 
ATOM   6033 C C6    . U   C 2 20  ? 132.704 146.502 96.040  1.00 136.62 ? 20  U   C C6    1 
ATOM   6034 P P     . C   C 2 21  ? 132.687 152.242 96.717  1.00 134.03 ? 21  C   C P     1 
ATOM   6035 O OP1   . C   C 2 21  ? 133.196 153.635 96.781  1.00 134.03 ? 21  C   C OP1   1 
ATOM   6036 O OP2   . C   C 2 21  ? 132.424 151.500 97.976  1.00 134.03 ? 21  C   C OP2   1 
ATOM   6037 O "O5'" . C   C 2 21  ? 131.347 152.245 95.853  1.00 134.03 ? 21  C   C "O5'" 1 
ATOM   6038 C "C5'" . C   C 2 21  ? 131.243 153.017 94.665  1.00 134.03 ? 21  C   C "C5'" 1 
ATOM   6039 C "C4'" . C   C 2 21  ? 129.957 152.734 93.927  1.00 134.03 ? 21  C   C "C4'" 1 
ATOM   6040 O "O4'" . C   C 2 21  ? 129.849 151.314 93.662  1.00 134.03 ? 21  C   C "O4'" 1 
ATOM   6041 C "C3'" . C   C 2 21  ? 128.668 153.079 94.660  1.00 134.03 ? 21  C   C "C3'" 1 
ATOM   6042 O "O3'" . C   C 2 21  ? 128.326 154.451 94.542  1.00 134.03 ? 21  C   C "O3'" 1 
ATOM   6043 C "C2'" . C   C 2 21  ? 127.647 152.152 94.012  1.00 134.03 ? 21  C   C "C2'" 1 
ATOM   6044 O "O2'" . C   C 2 21  ? 127.172 152.703 92.793  1.00 134.03 ? 21  C   C "O2'" 1 
ATOM   6045 C "C1'" . C   C 2 21  ? 128.494 150.920 93.687  1.00 134.03 ? 21  C   C "C1'" 1 
ATOM   6046 N N1    . C   C 2 21  ? 128.329 149.812 94.657  1.00 134.03 ? 21  C   C N1    1 
ATOM   6047 C C2    . C   C 2 21  ? 127.104 149.141 94.751  1.00 134.03 ? 21  C   C C2    1 
ATOM   6048 O O2    . C   C 2 21  ? 126.154 149.482 94.039  1.00 134.03 ? 21  C   C O2    1 
ATOM   6049 N N3    . C   C 2 21  ? 126.966 148.118 95.623  1.00 134.03 ? 21  C   C N3    1 
ATOM   6050 C C4    . C   C 2 21  ? 127.992 147.740 96.378  1.00 134.03 ? 21  C   C C4    1 
ATOM   6051 N N4    . C   C 2 21  ? 127.789 146.723 97.221  1.00 134.03 ? 21  C   C N4    1 
ATOM   6052 C C5    . C   C 2 21  ? 129.251 148.400 96.306  1.00 134.03 ? 21  C   C C5    1 
ATOM   6053 C C6    . C   C 2 21  ? 129.379 149.408 95.432  1.00 134.03 ? 21  C   C C6    1 
ATOM   6054 P P     . U   C 2 22  ? 127.036 155.046 95.298  1.00 127.46 ? 22  U   C P     1 
ATOM   6055 O OP1   . U   C 2 22  ? 127.175 156.524 95.327  1.00 127.46 ? 22  U   C OP1   1 
ATOM   6056 O OP2   . U   C 2 22  ? 126.870 154.301 96.572  1.00 127.46 ? 22  U   C OP2   1 
ATOM   6057 O "O5'" . U   C 2 22  ? 125.806 154.683 94.348  1.00 127.46 ? 22  U   C "O5'" 1 
ATOM   6058 C "C5'" . U   C 2 22  ? 125.013 155.699 93.743  1.00 127.46 ? 22  U   C "C5'" 1 
ATOM   6059 C "C4'" . U   C 2 22  ? 123.563 155.596 94.153  1.00 127.46 ? 22  U   C "C4'" 1 
ATOM   6060 O "O4'" . U   C 2 22  ? 123.017 154.325 93.715  1.00 127.46 ? 22  U   C "O4'" 1 
ATOM   6061 C "C3'" . U   C 2 22  ? 123.303 155.617 95.650  1.00 127.46 ? 22  U   C "C3'" 1 
ATOM   6062 O "O3'" . U   C 2 22  ? 123.261 156.923 96.185  1.00 127.46 ? 22  U   C "O3'" 1 
ATOM   6063 C "C2'" . U   C 2 22  ? 121.988 154.860 95.787  1.00 127.46 ? 22  U   C "C2'" 1 
ATOM   6064 O "O2'" . U   C 2 22  ? 120.890 155.704 95.477  1.00 127.46 ? 22  U   C "O2'" 1 
ATOM   6065 C "C1'" . U   C 2 22  ? 122.120 153.819 94.682  1.00 127.46 ? 22  U   C "C1'" 1 
ATOM   6066 N N1    . U   C 2 22  ? 122.653 152.523 95.159  1.00 127.46 ? 22  U   C N1    1 
ATOM   6067 C C2    . U   C 2 22  ? 121.772 151.515 95.508  1.00 127.46 ? 22  U   C C2    1 
ATOM   6068 O O2    . U   C 2 22  ? 120.561 151.646 95.471  1.00 127.46 ? 22  U   C O2    1 
ATOM   6069 N N3    . U   C 2 22  ? 122.379 150.344 95.897  1.00 127.46 ? 22  U   C N3    1 
ATOM   6070 C C4    . U   C 2 22  ? 123.728 150.085 95.970  1.00 127.46 ? 22  U   C C4    1 
ATOM   6071 O O4    . U   C 2 22  ? 124.102 148.983 96.361  1.00 127.46 ? 22  U   C O4    1 
ATOM   6072 C C5    . U   C 2 22  ? 124.560 151.181 95.600  1.00 127.46 ? 22  U   C C5    1 
ATOM   6073 C C6    . U   C 2 22  ? 124.009 152.321 95.202  1.00 127.46 ? 22  U   C C6    1 
ATOM   6074 P P     . U   C 2 23  ? 123.693 157.140 97.709  1.00 95.09  ? 23  U   C P     1 
ATOM   6075 O OP1   . U   C 2 23  ? 122.880 156.156 98.474  1.00 95.09  ? 23  U   C OP1   1 
ATOM   6076 O OP2   . U   C 2 23  ? 123.591 158.571 98.072  1.00 95.09  ? 23  U   C OP2   1 
ATOM   6077 O "O5'" . U   C 2 23  ? 125.240 156.746 97.706  1.00 95.09  ? 23  U   C "O5'" 1 
ATOM   6078 C "C5'" . U   C 2 23  ? 126.043 156.938 98.862  1.00 95.09  ? 23  U   C "C5'" 1 
ATOM   6079 C "C4'" . U   C 2 23  ? 125.316 156.452 100.083 1.00 95.09  ? 23  U   C "C4'" 1 
ATOM   6080 O "O4'" . U   C 2 23  ? 124.976 155.053 99.892  1.00 95.09  ? 23  U   C "O4'" 1 
ATOM   6081 C "C3'" . U   C 2 23  ? 126.072 156.541 101.398 1.00 95.09  ? 23  U   C "C3'" 1 
ATOM   6082 O "O3'" . U   C 2 23  ? 125.230 156.978 102.485 1.00 95.09  ? 23  U   C "O3'" 1 
ATOM   6083 C "C2'" . U   C 2 23  ? 126.572 155.112 101.614 1.00 95.09  ? 23  U   C "C2'" 1 
ATOM   6084 O "O2'" . U   C 2 23  ? 126.769 154.756 102.965 1.00 95.09  ? 23  U   C "O2'" 1 
ATOM   6085 C "C1'" . U   C 2 23  ? 125.469 154.280 100.965 1.00 95.09  ? 23  U   C "C1'" 1 
ATOM   6086 N N1    . U   C 2 23  ? 125.936 153.002 100.414 1.00 95.09  ? 23  U   C N1    1 
ATOM   6087 C C2    . U   C 2 23  ? 125.046 151.949 100.406 1.00 95.09  ? 23  U   C C2    1 
ATOM   6088 O O2    . U   C 2 23  ? 123.907 152.049 100.823 1.00 95.09  ? 23  U   C O2    1 
ATOM   6089 N N3    . U   C 2 23  ? 125.534 150.781 99.880  1.00 95.09  ? 23  U   C N3    1 
ATOM   6090 C C4    . U   C 2 23  ? 126.800 150.564 99.377  1.00 95.09  ? 23  U   C C4    1 
ATOM   6091 O O4    . U   C 2 23  ? 127.094 149.451 98.939  1.00 95.09  ? 23  U   C O4    1 
ATOM   6092 C C5    . U   C 2 23  ? 127.663 151.704 99.425  1.00 95.09  ? 23  U   C C5    1 
ATOM   6093 C C6    . U   C 2 23  ? 127.213 152.856 99.930  1.00 95.09  ? 23  U   C C6    1 
ATOM   6094 P P     . A   C 2 24  ? 123.640 156.692 102.611 1.00 87.05  ? 24  A   C P     1 
ATOM   6095 O OP1   . A   C 2 24  ? 122.832 156.759 101.368 1.00 87.05  ? 24  A   C OP1   1 
ATOM   6096 O OP2   . A   C 2 24  ? 123.210 157.591 103.703 1.00 87.05  ? 24  A   C OP2   1 
ATOM   6097 O "O5'" . A   C 2 24  ? 123.560 155.221 103.209 1.00 87.05  ? 24  A   C "O5'" 1 
ATOM   6098 C "C5'" . A   C 2 24  ? 124.050 154.943 104.511 1.00 87.05  ? 24  A   C "C5'" 1 
ATOM   6099 C "C4'" . A   C 2 24  ? 123.048 154.157 105.313 1.00 87.05  ? 24  A   C "C4'" 1 
ATOM   6100 O "O4'" . A   C 2 24  ? 121.721 154.700 105.084 1.00 87.05  ? 24  A   C "O4'" 1 
ATOM   6101 C "C3'" . A   C 2 24  ? 122.911 152.689 104.946 1.00 87.05  ? 24  A   C "C3'" 1 
ATOM   6102 O "O3'" . A   C 2 24  ? 123.910 151.871 105.528 1.00 87.05  ? 24  A   C "O3'" 1 
ATOM   6103 C "C2'" . A   C 2 24  ? 121.502 152.367 105.414 1.00 87.05  ? 24  A   C "C2'" 1 
ATOM   6104 O "O2'" . A   C 2 24  ? 121.464 152.214 106.825 1.00 87.05  ? 24  A   C "O2'" 1 
ATOM   6105 C "C1'" . A   C 2 24  ? 120.772 153.656 105.049 1.00 87.05  ? 24  A   C "C1'" 1 
ATOM   6106 N N9    . A   C 2 24  ? 120.217 153.581 103.687 1.00 87.05  ? 24  A   C N9    1 
ATOM   6107 C C8    . A   C 2 24  ? 119.875 152.445 102.998 1.00 87.05  ? 24  A   C C8    1 
ATOM   6108 N N7    . A   C 2 24  ? 119.400 152.676 101.799 1.00 87.05  ? 24  A   C N7    1 
ATOM   6109 C C5    . A   C 2 24  ? 119.430 154.060 101.693 1.00 87.05  ? 24  A   C C5    1 
ATOM   6110 C C6    . A   C 2 24  ? 119.055 154.935 100.659 1.00 87.05  ? 24  A   C C6    1 
ATOM   6111 N N6    . A   C 2 24  ? 118.558 154.530 99.488  1.00 87.05  ? 24  A   C N6    1 
ATOM   6112 N N1    . A   C 2 24  ? 119.211 156.260 100.870 1.00 87.05  ? 24  A   C N1    1 
ATOM   6113 C C2    . A   C 2 24  ? 119.710 156.666 102.044 1.00 87.05  ? 24  A   C C2    1 
ATOM   6114 N N3    . A   C 2 24  ? 120.097 155.942 103.091 1.00 87.05  ? 24  A   C N3    1 
ATOM   6115 C C4    . A   C 2 24  ? 119.927 154.631 102.851 1.00 87.05  ? 24  A   C C4    1 
ATOM   6116 P P     . C   C 2 25  ? 124.988 151.133 104.593 1.00 91.48  ? 25  C   C P     1 
ATOM   6117 O OP1   . C   C 2 25  ? 126.256 151.899 104.665 1.00 91.48  ? 25  C   C OP1   1 
ATOM   6118 O OP2   . C   C 2 25  ? 124.358 150.883 103.275 1.00 91.48  ? 25  C   C OP2   1 
ATOM   6119 O "O5'" . C   C 2 25  ? 125.204 149.717 105.289 1.00 91.48  ? 25  C   C "O5'" 1 
ATOM   6120 C "C5'" . C   C 2 25  ? 124.331 148.631 105.012 1.00 91.48  ? 25  C   C "C5'" 1 
ATOM   6121 C "C4'" . C   C 2 25  ? 123.774 148.035 106.279 1.00 91.48  ? 25  C   C "C4'" 1 
ATOM   6122 O "O4'" . C   C 2 25  ? 123.009 149.039 106.994 1.00 91.48  ? 25  C   C "O4'" 1 
ATOM   6123 C "C3'" . C   C 2 25  ? 122.796 146.886 106.106 1.00 91.48  ? 25  C   C "C3'" 1 
ATOM   6124 O "O3'" . C   C 2 25  ? 123.429 145.642 105.862 1.00 91.48  ? 25  C   C "O3'" 1 
ATOM   6125 C "C2'" . C   C 2 25  ? 122.005 146.922 107.409 1.00 91.48  ? 25  C   C "C2'" 1 
ATOM   6126 O "O2'" . C   C 2 25  ? 122.737 146.304 108.457 1.00 91.48  ? 25  C   C "O2'" 1 
ATOM   6127 C "C1'" . C   C 2 25  ? 121.941 148.426 107.687 1.00 91.48  ? 25  C   C "C1'" 1 
ATOM   6128 N N1    . C   C 2 25  ? 120.662 149.028 107.241 1.00 91.48  ? 25  C   C N1    1 
ATOM   6129 C C2    . C   C 2 25  ? 119.744 149.408 108.222 1.00 91.48  ? 25  C   C C2    1 
ATOM   6130 O O2    . C   C 2 25  ? 120.042 149.241 109.414 1.00 91.48  ? 25  C   C O2    1 
ATOM   6131 N N3    . C   C 2 25  ? 118.565 149.958 107.853 1.00 91.48  ? 25  C   C N3    1 
ATOM   6132 C C4    . C   C 2 25  ? 118.282 150.124 106.560 1.00 91.48  ? 25  C   C C4    1 
ATOM   6133 N N4    . C   C 2 25  ? 117.105 150.669 106.242 1.00 91.48  ? 25  C   C N4    1 
ATOM   6134 C C5    . C   C 2 25  ? 119.193 149.739 105.536 1.00 91.48  ? 25  C   C C5    1 
ATOM   6135 C C6    . C   C 2 25  ? 120.356 149.198 105.919 1.00 91.48  ? 25  C   C C6    1 
ATOM   6136 P P     . A   C 2 26  ? 123.052 144.782 104.556 1.00 115.28 ? 26  A   C P     1 
ATOM   6137 O OP1   . A   C 2 26  ? 123.475 143.379 104.791 1.00 115.28 ? 26  A   C OP1   1 
ATOM   6138 O OP2   . A   C 2 26  ? 123.556 145.511 103.365 1.00 115.28 ? 26  A   C OP2   1 
ATOM   6139 O "O5'" . A   C 2 26  ? 121.459 144.812 104.513 1.00 115.28 ? 26  A   C "O5'" 1 
ATOM   6140 C "C5'" . A   C 2 26  ? 120.683 144.156 105.506 1.00 115.28 ? 26  A   C "C5'" 1 
ATOM   6141 C "C4'" . A   C 2 26  ? 119.230 144.546 105.412 1.00 115.28 ? 26  A   C "C4'" 1 
ATOM   6142 O "O4'" . A   C 2 26  ? 119.107 145.993 105.451 1.00 115.28 ? 26  A   C "O4'" 1 
ATOM   6143 C "C3'" . A   C 2 26  ? 118.525 144.154 104.125 1.00 115.28 ? 26  A   C "C3'" 1 
ATOM   6144 O "O3'" . A   C 2 26  ? 118.106 142.801 104.114 1.00 115.28 ? 26  A   C "O3'" 1 
ATOM   6145 C "C2'" . A   C 2 26  ? 117.381 145.155 104.056 1.00 115.28 ? 26  A   C "C2'" 1 
ATOM   6146 O "O2'" . A   C 2 26  ? 116.335 144.784 104.941 1.00 115.28 ? 26  A   C "O2'" 1 
ATOM   6147 C "C1'" . A   C 2 26  ? 118.054 146.410 104.607 1.00 115.28 ? 26  A   C "C1'" 1 
ATOM   6148 N N9    . A   C 2 26  ? 118.624 147.243 103.531 1.00 115.28 ? 26  A   C N9    1 
ATOM   6149 C C8    . A   C 2 26  ? 119.939 147.335 103.151 1.00 115.28 ? 26  A   C C8    1 
ATOM   6150 N N7    . A   C 2 26  ? 120.146 148.162 102.155 1.00 115.28 ? 26  A   C N7    1 
ATOM   6151 C C5    . A   C 2 26  ? 118.881 148.645 101.858 1.00 115.28 ? 26  A   C C5    1 
ATOM   6152 C C6    . A   C 2 26  ? 118.423 149.561 100.896 1.00 115.28 ? 26  A   C C6    1 
ATOM   6153 N N6    . A   C 2 26  ? 119.221 150.176 100.021 1.00 115.28 ? 26  A   C N6    1 
ATOM   6154 N N1    . A   C 2 26  ? 117.099 149.827 100.862 1.00 115.28 ? 26  A   C N1    1 
ATOM   6155 C C2    . A   C 2 26  ? 116.300 149.209 101.741 1.00 115.28 ? 26  A   C C2    1 
ATOM   6156 N N3    . A   C 2 26  ? 116.612 148.330 102.690 1.00 115.28 ? 26  A   C N3    1 
ATOM   6157 C C4    . A   C 2 26  ? 117.933 148.088 102.696 1.00 115.28 ? 26  A   C C4    1 
ATOM   6158 P P     . A   C 2 27  ? 118.700 141.787 103.019 1.00 129.33 ? 27  A   C P     1 
ATOM   6159 O OP1   . A   C 2 27  ? 118.068 140.459 103.229 1.00 129.33 ? 27  A   C OP1   1 
ATOM   6160 O OP2   . A   C 2 27  ? 120.180 141.908 103.033 1.00 129.33 ? 27  A   C OP2   1 
ATOM   6161 O "O5'" . A   C 2 27  ? 118.169 142.369 101.636 1.00 129.33 ? 27  A   C "O5'" 1 
ATOM   6162 C "C5'" . A   C 2 27  ? 116.777 142.500 101.397 1.00 129.33 ? 27  A   C "C5'" 1 
ATOM   6163 C "C4'" . A   C 2 27  ? 116.490 143.421 100.239 1.00 129.33 ? 27  A   C "C4'" 1 
ATOM   6164 O "O4'" . A   C 2 27  ? 116.897 144.777 100.560 1.00 129.33 ? 27  A   C "O4'" 1 
ATOM   6165 C "C3'" . A   C 2 27  ? 117.224 143.128 98.943  1.00 129.33 ? 27  A   C "C3'" 1 
ATOM   6166 O "O3'" . A   C 2 27  ? 116.680 142.040 98.218  1.00 129.33 ? 27  A   C "O3'" 1 
ATOM   6167 C "C2'" . A   C 2 27  ? 117.134 144.462 98.217  1.00 129.33 ? 27  A   C "C2'" 1 
ATOM   6168 O "O2'" . A   C 2 27  ? 115.838 144.647 97.667  1.00 129.33 ? 27  A   C "O2'" 1 
ATOM   6169 C "C1'" . A   C 2 27  ? 117.310 145.440 99.380  1.00 129.33 ? 27  A   C "C1'" 1 
ATOM   6170 N N9    . A   C 2 27  ? 118.719 145.848 99.520  1.00 129.33 ? 27  A   C N9    1 
ATOM   6171 C C8    . A   C 2 27  ? 119.684 145.365 100.368 1.00 129.33 ? 27  A   C C8    1 
ATOM   6172 N N7    . A   C 2 27  ? 120.852 145.947 100.217 1.00 129.33 ? 27  A   C N7    1 
ATOM   6173 C C5    . A   C 2 27  ? 120.641 146.868 99.199  1.00 129.33 ? 27  A   C C5    1 
ATOM   6174 C C6    . A   C 2 27  ? 121.479 147.804 98.565  1.00 129.33 ? 27  A   C C6    1 
ATOM   6175 N N6    . A   C 2 27  ? 122.767 147.979 98.868  1.00 129.33 ? 27  A   C N6    1 
ATOM   6176 N N1    . A   C 2 27  ? 120.945 148.568 97.584  1.00 129.33 ? 27  A   C N1    1 
ATOM   6177 C C2    . A   C 2 27  ? 119.656 148.395 97.270  1.00 129.33 ? 27  A   C C2    1 
ATOM   6178 N N3    . A   C 2 27  ? 118.770 147.553 97.792  1.00 129.33 ? 27  A   C N3    1 
ATOM   6179 C C4    . A   C 2 27  ? 119.333 146.811 98.760  1.00 129.33 ? 27  A   C C4    1 
ATOM   6180 P P     . G   C 2 28  ? 117.663 140.954 97.556  1.00 143.73 ? 28  G   C P     1 
ATOM   6181 O OP1   . G   C 2 28  ? 116.829 139.861 96.995  1.00 143.73 ? 28  G   C OP1   1 
ATOM   6182 O OP2   . G   C 2 28  ? 118.729 140.636 98.540  1.00 143.73 ? 28  G   C OP2   1 
ATOM   6183 O "O5'" . G   C 2 28  ? 118.330 141.736 96.338  1.00 143.73 ? 28  G   C "O5'" 1 
ATOM   6184 C "C5'" . G   C 2 28  ? 117.533 142.196 95.260  1.00 143.73 ? 28  G   C "C5'" 1 
ATOM   6185 C "C4'" . G   C 2 28  ? 118.273 143.167 94.373  1.00 143.73 ? 28  G   C "C4'" 1 
ATOM   6186 O "O4'" . G   C 2 28  ? 118.697 144.329 95.132  1.00 143.73 ? 28  G   C "O4'" 1 
ATOM   6187 C "C3'" . G   C 2 28  ? 119.560 142.672 93.737  1.00 143.73 ? 28  G   C "C3'" 1 
ATOM   6188 O "O3'" . G   C 2 28  ? 119.349 141.813 92.631  1.00 143.73 ? 28  G   C "O3'" 1 
ATOM   6189 C "C2'" . G   C 2 28  ? 120.257 143.975 93.372  1.00 143.73 ? 28  G   C "C2'" 1 
ATOM   6190 O "O2'" . G   C 2 28  ? 119.691 144.535 92.197  1.00 143.73 ? 28  G   C "O2'" 1 
ATOM   6191 C "C1'" . G   C 2 28  ? 119.876 144.861 94.561  1.00 143.73 ? 28  G   C "C1'" 1 
ATOM   6192 N N9    . G   C 2 28  ? 120.948 144.893 95.573  1.00 143.73 ? 28  G   C N9    1 
ATOM   6193 C C8    . G   C 2 28  ? 121.021 144.259 96.789  1.00 143.73 ? 28  G   C C8    1 
ATOM   6194 N N7    . G   C 2 28  ? 122.137 144.511 97.424  1.00 143.73 ? 28  G   C N7    1 
ATOM   6195 C C5    . G   C 2 28  ? 122.844 145.352 96.573  1.00 143.73 ? 28  G   C C5    1 
ATOM   6196 C C6    . G   C 2 28  ? 124.121 145.963 96.703  1.00 143.73 ? 28  G   C C6    1 
ATOM   6197 O O6    . G   C 2 28  ? 124.944 145.897 97.625  1.00 143.73 ? 28  G   C O6    1 
ATOM   6198 N N1    . G   C 2 28  ? 124.430 146.734 95.589  1.00 143.73 ? 28  G   C N1    1 
ATOM   6199 C C2    . G   C 2 28  ? 123.631 146.902 94.486  1.00 143.73 ? 28  G   C C2    1 
ATOM   6200 N N2    . G   C 2 28  ? 124.119 147.694 93.521  1.00 143.73 ? 28  G   C N2    1 
ATOM   6201 N N3    . G   C 2 28  ? 122.442 146.345 94.354  1.00 143.73 ? 28  G   C N3    1 
ATOM   6202 C C4    . G   C 2 28  ? 122.120 145.590 95.425  1.00 143.73 ? 28  G   C C4    1 
ATOM   6203 P P     . A   C 2 29  ? 120.502 140.785 92.185  1.00 150.35 ? 29  A   C P     1 
ATOM   6204 O OP1   . A   C 2 29  ? 119.912 139.816 91.227  1.00 150.35 ? 29  A   C OP1   1 
ATOM   6205 O OP2   . A   C 2 29  ? 121.171 140.287 93.414  1.00 150.35 ? 29  A   C OP2   1 
ATOM   6206 O "O5'" . A   C 2 29  ? 121.543 141.694 91.392  1.00 150.35 ? 29  A   C "O5'" 1 
ATOM   6207 C "C5'" . A   C 2 29  ? 121.159 142.362 90.200  1.00 150.35 ? 29  A   C "C5'" 1 
ATOM   6208 C "C4'" . A   C 2 29  ? 122.176 143.394 89.782  1.00 150.35 ? 29  A   C "C4'" 1 
ATOM   6209 O "O4'" . A   C 2 29  ? 122.326 144.398 90.821  1.00 150.35 ? 29  A   C "O4'" 1 
ATOM   6210 C "C3'" . A   C 2 29  ? 123.593 142.895 89.556  1.00 150.35 ? 29  A   C "C3'" 1 
ATOM   6211 O "O3'" . A   C 2 29  ? 123.771 142.250 88.307  1.00 150.35 ? 29  A   C "O3'" 1 
ATOM   6212 C "C2'" . A   C 2 29  ? 124.411 144.169 89.710  1.00 150.35 ? 29  A   C "C2'" 1 
ATOM   6213 O "O2'" . A   C 2 29  ? 124.311 144.974 88.545  1.00 150.35 ? 29  A   C "O2'" 1 
ATOM   6214 C "C1'" . A   C 2 29  ? 123.661 144.865 90.845  1.00 150.35 ? 29  A   C "C1'" 1 
ATOM   6215 N N9    . A   C 2 29  ? 124.254 144.537 92.153  1.00 150.35 ? 29  A   C N9    1 
ATOM   6216 C C8    . A   C 2 29  ? 123.749 143.719 93.132  1.00 150.35 ? 29  A   C C8    1 
ATOM   6217 N N7    . A   C 2 29  ? 124.524 143.618 94.183  1.00 150.35 ? 29  A   C N7    1 
ATOM   6218 C C5    . A   C 2 29  ? 125.615 144.416 93.869  1.00 150.35 ? 29  A   C C5    1 
ATOM   6219 C C6    . A   C 2 29  ? 126.788 144.731 94.572  1.00 150.35 ? 29  A   C C6    1 
ATOM   6220 N N6    . A   C 2 29  ? 127.056 144.249 95.784  1.00 150.35 ? 29  A   C N6    1 
ATOM   6221 N N1    . A   C 2 29  ? 127.680 145.559 93.983  1.00 150.35 ? 29  A   C N1    1 
ATOM   6222 C C2    . A   C 2 29  ? 127.398 146.036 92.764  1.00 150.35 ? 29  A   C C2    1 
ATOM   6223 N N3    . A   C 2 29  ? 126.328 145.813 92.003  1.00 150.35 ? 29  A   C N3    1 
ATOM   6224 C C4    . A   C 2 29  ? 125.465 144.986 92.620  1.00 150.35 ? 29  A   C C4    1 
ATOM   6225 P P     . G   C 2 30  ? 124.761 140.990 88.189  1.00 155.54 ? 30  G   C P     1 
ATOM   6226 O OP1   . G   C 2 30  ? 124.625 140.421 86.824  1.00 155.54 ? 30  G   C OP1   1 
ATOM   6227 O OP2   . G   C 2 30  ? 124.543 140.121 89.373  1.00 155.54 ? 30  G   C OP2   1 
ATOM   6228 O "O5'" . G   C 2 30  ? 126.215 141.630 88.310  1.00 155.54 ? 30  G   C "O5'" 1 
ATOM   6229 C "C5'" . G   C 2 30  ? 126.648 142.619 87.390  1.00 155.54 ? 30  G   C "C5'" 1 
ATOM   6230 C "C4'" . G   C 2 30  ? 127.901 143.313 87.860  1.00 155.54 ? 30  G   C "C4'" 1 
ATOM   6231 O "O4'" . G   C 2 30  ? 127.711 143.840 89.197  1.00 155.54 ? 30  G   C "O4'" 1 
ATOM   6232 C "C3'" . G   C 2 30  ? 129.143 142.448 87.984  1.00 155.54 ? 30  G   C "C3'" 1 
ATOM   6233 O "O3'" . G   C 2 30  ? 129.775 142.214 86.738  1.00 155.54 ? 30  G   C "O3'" 1 
ATOM   6234 C "C2'" . G   C 2 30  ? 130.003 143.244 88.960  1.00 155.54 ? 30  G   C "C2'" 1 
ATOM   6235 O "O2'" . G   C 2 30  ? 130.663 144.310 88.293  1.00 155.54 ? 30  G   C "O2'" 1 
ATOM   6236 C "C1'" . G   C 2 30  ? 128.943 143.839 89.890  1.00 155.54 ? 30  G   C "C1'" 1 
ATOM   6237 N N9    . G   C 2 30  ? 128.800 143.074 91.144  1.00 155.54 ? 30  G   C N9    1 
ATOM   6238 C C8    . G   C 2 30  ? 127.761 142.264 91.532  1.00 155.54 ? 30  G   C C8    1 
ATOM   6239 N N7    . G   C 2 30  ? 127.941 141.732 92.712  1.00 155.54 ? 30  G   C N7    1 
ATOM   6240 C C5    . G   C 2 30  ? 129.170 142.224 93.132  1.00 155.54 ? 30  G   C C5    1 
ATOM   6241 C C6    . G   C 2 30  ? 129.900 142.000 94.331  1.00 155.54 ? 30  G   C C6    1 
ATOM   6242 O O6    . G   C 2 30  ? 129.591 141.297 95.300  1.00 155.54 ? 30  G   C O6    1 
ATOM   6243 N N1    . G   C 2 30  ? 131.105 142.697 94.341  1.00 155.54 ? 30  G   C N1    1 
ATOM   6244 C C2    . G   C 2 30  ? 131.553 143.505 93.326  1.00 155.54 ? 30  G   C C2    1 
ATOM   6245 N N2    . G   C 2 30  ? 132.739 144.104 93.497  1.00 155.54 ? 30  G   C N2    1 
ATOM   6246 N N3    . G   C 2 30  ? 130.883 143.719 92.206  1.00 155.54 ? 30  G   C N3    1 
ATOM   6247 C C4    . G   C 2 30  ? 129.711 143.053 92.175  1.00 155.54 ? 30  G   C C4    1 
ATOM   6248 P P     . U   C 2 31  ? 129.489 140.857 85.927  1.00 163.27 ? 31  U   C P     1 
ATOM   6249 O OP1   . U   C 2 31  ? 128.480 141.152 84.878  1.00 163.27 ? 31  U   C OP1   1 
ATOM   6250 O OP2   . U   C 2 31  ? 129.226 139.779 86.913  1.00 163.27 ? 31  U   C OP2   1 
ATOM   6251 O "O5'" . U   C 2 31  ? 130.874 140.540 85.207  1.00 163.27 ? 31  U   C "O5'" 1 
ATOM   6252 C "C5'" . U   C 2 31  ? 131.797 139.624 85.776  1.00 163.27 ? 31  U   C "C5'" 1 
ATOM   6253 C "C4'" . U   C 2 31  ? 132.864 140.333 86.571  1.00 163.27 ? 31  U   C "C4'" 1 
ATOM   6254 O "O4'" . U   C 2 31  ? 132.242 141.192 87.562  1.00 163.27 ? 31  U   C "O4'" 1 
ATOM   6255 C "C3'" . U   C 2 31  ? 133.788 139.438 87.383  1.00 163.27 ? 31  U   C "C3'" 1 
ATOM   6256 O "O3'" . U   C 2 31  ? 134.837 138.882 86.612  1.00 163.27 ? 31  U   C "O3'" 1 
ATOM   6257 C "C2'" . U   C 2 31  ? 134.266 140.368 88.490  1.00 163.27 ? 31  U   C "C2'" 1 
ATOM   6258 O "O2'" . U   C 2 31  ? 135.290 141.229 88.014  1.00 163.27 ? 31  U   C "O2'" 1 
ATOM   6259 C "C1'" . U   C 2 31  ? 133.012 141.203 88.745  1.00 163.27 ? 31  U   C "C1'" 1 
ATOM   6260 N N1    . U   C 2 31  ? 132.186 140.656 89.847  1.00 163.27 ? 31  U   C N1    1 
ATOM   6261 C C2    . U   C 2 31  ? 132.544 140.971 91.143  1.00 163.27 ? 31  U   C C2    1 
ATOM   6262 O O2    . U   C 2 31  ? 133.506 141.669 91.413  1.00 163.27 ? 31  U   C O2    1 
ATOM   6263 N N3    . U   C 2 31  ? 131.736 140.433 92.114  1.00 163.27 ? 31  U   C N3    1 
ATOM   6264 C C4    . U   C 2 31  ? 130.627 139.633 91.926  1.00 163.27 ? 31  U   C C4    1 
ATOM   6265 O O4    . U   C 2 31  ? 130.001 139.227 92.906  1.00 163.27 ? 31  U   C O4    1 
ATOM   6266 C C5    . U   C 2 31  ? 130.319 139.355 90.558  1.00 163.27 ? 31  U   C C5    1 
ATOM   6267 C C6    . U   C 2 31  ? 131.089 139.864 89.592  1.00 163.27 ? 31  U   C C6    1 
ATOM   6268 P P     . G   C 2 32  ? 134.953 137.288 86.444  1.00 156.62 ? 32  G   C P     1 
ATOM   6269 O OP1   . G   C 2 32  ? 136.274 136.981 85.839  1.00 156.62 ? 32  G   C OP1   1 
ATOM   6270 O OP2   . G   C 2 32  ? 133.713 136.805 85.785  1.00 156.62 ? 32  G   C OP2   1 
ATOM   6271 O "O5'" . G   C 2 32  ? 134.957 136.748 87.941  1.00 156.62 ? 32  G   C "O5'" 1 
ATOM   6272 C "C5'" . G   C 2 32  ? 136.090 136.078 88.473  1.00 156.62 ? 32  G   C "C5'" 1 
ATOM   6273 C "C4'" . G   C 2 32  ? 136.927 136.999 89.325  1.00 156.62 ? 32  G   C "C4'" 1 
ATOM   6274 O "O4'" . G   C 2 32  ? 136.134 138.139 89.744  1.00 156.62 ? 32  G   C "O4'" 1 
ATOM   6275 C "C3'" . G   C 2 32  ? 137.448 136.405 90.624  1.00 156.62 ? 32  G   C "C3'" 1 
ATOM   6276 O "O3'" . G   C 2 32  ? 138.623 135.635 90.437  1.00 156.62 ? 32  G   C "O3'" 1 
ATOM   6277 C "C2'" . G   C 2 32  ? 137.660 137.637 91.496  1.00 156.62 ? 32  G   C "C2'" 1 
ATOM   6278 O "O2'" . G   C 2 32  ? 138.879 138.283 91.163  1.00 156.62 ? 32  G   C "O2'" 1 
ATOM   6279 C "C1'" . G   C 2 32  ? 136.502 138.531 91.049  1.00 156.62 ? 32  G   C "C1'" 1 
ATOM   6280 N N9    . G   C 2 32  ? 135.315 138.407 91.919  1.00 156.62 ? 32  G   C N9    1 
ATOM   6281 C C8    . G   C 2 32  ? 134.045 138.102 91.495  1.00 156.62 ? 32  G   C C8    1 
ATOM   6282 N N7    . G   C 2 32  ? 133.173 138.061 92.462  1.00 156.62 ? 32  G   C N7    1 
ATOM   6283 C C5    . G   C 2 32  ? 133.907 138.364 93.598  1.00 156.62 ? 32  G   C C5    1 
ATOM   6284 C C6    . G   C 2 32  ? 133.492 138.468 94.950  1.00 156.62 ? 32  G   C C6    1 
ATOM   6285 O O6    . G   C 2 32  ? 132.359 138.309 95.420  1.00 156.62 ? 32  G   C O6    1 
ATOM   6286 N N1    . G   C 2 32  ? 134.553 138.792 95.786  1.00 156.62 ? 32  G   C N1    1 
ATOM   6287 C C2    . G   C 2 32  ? 135.849 138.992 95.377  1.00 156.62 ? 32  G   C C2    1 
ATOM   6288 N N2    . G   C 2 32  ? 136.745 139.299 96.325  1.00 156.62 ? 32  G   C N2    1 
ATOM   6289 N N3    . G   C 2 32  ? 136.246 138.898 94.118  1.00 156.62 ? 32  G   C N3    1 
ATOM   6290 C C4    . G   C 2 32  ? 135.233 138.584 93.284  1.00 156.62 ? 32  G   C C4    1 
ATOM   6291 P P     . U   C 2 33  ? 138.670 134.099 90.906  1.00 151.12 ? 33  U   C P     1 
ATOM   6292 O OP1   . U   C 2 33  ? 139.573 133.363 89.984  1.00 151.12 ? 33  U   C OP1   1 
ATOM   6293 O OP2   . U   C 2 33  ? 137.273 133.631 91.093  1.00 151.12 ? 33  U   C OP2   1 
ATOM   6294 O "O5'" . U   C 2 33  ? 139.366 134.156 92.337  1.00 151.12 ? 33  U   C "O5'" 1 
ATOM   6295 C "C5'" . U   C 2 33  ? 140.621 134.796 92.515  1.00 151.12 ? 33  U   C "C5'" 1 
ATOM   6296 C "C4'" . U   C 2 33  ? 140.809 135.240 93.943  1.00 151.12 ? 33  U   C "C4'" 1 
ATOM   6297 O "O4'" . U   C 2 33  ? 139.850 136.285 94.256  1.00 151.12 ? 33  U   C "O4'" 1 
ATOM   6298 C "C3'" . U   C 2 33  ? 140.561 134.174 95.000  1.00 151.12 ? 33  U   C "C3'" 1 
ATOM   6299 O "O3'" . U   C 2 33  ? 141.688 133.341 95.209  1.00 151.12 ? 33  U   C "O3'" 1 
ATOM   6300 C "C2'" . U   C 2 33  ? 140.173 134.993 96.223  1.00 151.12 ? 33  U   C "C2'" 1 
ATOM   6301 O "O2'" . U   C 2 33  ? 141.326 135.527 96.855  1.00 151.12 ? 33  U   C "O2'" 1 
ATOM   6302 C "C1'" . U   C 2 33  ? 139.396 136.145 95.585  1.00 151.12 ? 33  U   C "C1'" 1 
ATOM   6303 N N1    . U   C 2 33  ? 137.934 135.906 95.552  1.00 151.12 ? 33  U   C N1    1 
ATOM   6304 C C2    . U   C 2 33  ? 137.200 136.023 96.720  1.00 151.12 ? 33  U   C C2    1 
ATOM   6305 O O2    . U   C 2 33  ? 137.701 136.299 97.797  1.00 151.12 ? 33  U   C O2    1 
ATOM   6306 N N3    . U   C 2 33  ? 135.850 135.796 96.582  1.00 151.12 ? 33  U   C N3    1 
ATOM   6307 C C4    . U   C 2 33  ? 135.174 135.479 95.421  1.00 151.12 ? 33  U   C C4    1 
ATOM   6308 O O4    . U   C 2 33  ? 133.955 135.302 95.439  1.00 151.12 ? 33  U   C O4    1 
ATOM   6309 C C5    . U   C 2 33  ? 136.001 135.385 94.259  1.00 151.12 ? 33  U   C C5    1 
ATOM   6310 C C6    . U   C 2 33  ? 137.314 135.600 94.364  1.00 151.12 ? 33  U   C C6    1 
ATOM   6311 P P     . C   C 2 34  ? 141.494 131.776 95.516  1.00 145.82 ? 34  C   C P     1 
ATOM   6312 O OP1   . C   C 2 34  ? 142.814 131.111 95.371  1.00 145.82 ? 34  C   C OP1   1 
ATOM   6313 O OP2   . C   C 2 34  ? 140.336 131.292 94.723  1.00 145.82 ? 34  C   C OP2   1 
ATOM   6314 O "O5'" . C   C 2 34  ? 141.091 131.734 97.055  1.00 145.82 ? 34  C   C "O5'" 1 
ATOM   6315 C "C5'" . C   C 2 34  ? 141.939 132.294 98.046  1.00 145.82 ? 34  C   C "C5'" 1 
ATOM   6316 C "C4'" . C   C 2 34  ? 141.193 132.537 99.334  1.00 145.82 ? 34  C   C "C4'" 1 
ATOM   6317 O "O4'" . C   C 2 34  ? 140.113 133.479 99.102  1.00 145.82 ? 34  C   C "O4'" 1 
ATOM   6318 C "C3'" . C   C 2 34  ? 140.501 131.325 99.938  1.00 145.82 ? 34  C   C "C3'" 1 
ATOM   6319 O "O3'" . C   C 2 34  ? 141.379 130.500 100.682 1.00 145.82 ? 34  C   C "O3'" 1 
ATOM   6320 C "C2'" . C   C 2 34  ? 139.398 131.955 100.777 1.00 145.82 ? 34  C   C "C2'" 1 
ATOM   6321 O "O2'" . C   C 2 34  ? 139.921 132.450 102.001 1.00 145.82 ? 34  C   C "O2'" 1 
ATOM   6322 C "C1'" . C   C 2 34  ? 139.003 133.148 99.908  1.00 145.82 ? 34  C   C "C1'" 1 
ATOM   6323 N N1    . C   C 2 34  ? 137.848 132.852 99.028  1.00 145.82 ? 34  C   C N1    1 
ATOM   6324 C C2    . C   C 2 34  ? 136.569 132.807 99.586  1.00 145.82 ? 34  C   C C2    1 
ATOM   6325 O O2    . C   C 2 34  ? 136.440 133.007 100.801 1.00 145.82 ? 34  C   C O2    1 
ATOM   6326 N N3    . C   C 2 34  ? 135.505 132.547 98.793  1.00 145.82 ? 34  C   C N3    1 
ATOM   6327 C C4    . C   C 2 34  ? 135.682 132.338 97.488  1.00 145.82 ? 34  C   C C4    1 
ATOM   6328 N N4    . C   C 2 34  ? 134.605 132.084 96.743  1.00 145.82 ? 34  C   C N4    1 
ATOM   6329 C C5    . C   C 2 34  ? 136.974 132.381 96.890  1.00 145.82 ? 34  C   C C5    1 
ATOM   6330 C C6    . C   C 2 34  ? 138.017 132.640 97.689  1.00 145.82 ? 34  C   C C6    1 
ATOM   6331 P P     . U   C 2 35  ? 141.104 128.920 100.783 1.00 138.97 ? 35  U   C P     1 
ATOM   6332 O OP1   . U   C 2 35  ? 142.391 128.237 101.069 1.00 138.97 ? 35  U   C OP1   1 
ATOM   6333 O OP2   . U   C 2 35  ? 140.309 128.535 99.591  1.00 138.97 ? 35  U   C OP2   1 
ATOM   6334 O "O5'" . U   C 2 35  ? 140.163 128.771 102.060 1.00 138.97 ? 35  U   C "O5'" 1 
ATOM   6335 C "C5'" . U   C 2 35  ? 140.412 129.526 103.240 1.00 138.97 ? 35  U   C "C5'" 1 
ATOM   6336 C "C4'" . U   C 2 35  ? 139.172 129.666 104.090 1.00 138.97 ? 35  U   C "C4'" 1 
ATOM   6337 O "O4'" . U   C 2 35  ? 138.038 129.980 103.236 1.00 138.97 ? 35  U   C "O4'" 1 
ATOM   6338 C "C3'" . U   C 2 35  ? 138.782 128.421 104.881 1.00 138.97 ? 35  U   C "C3'" 1 
ATOM   6339 O "O3'" . U   C 2 35  ? 138.232 128.811 106.138 1.00 138.97 ? 35  U   C "O3'" 1 
ATOM   6340 C "C2'" . U   C 2 35  ? 137.700 127.786 104.011 1.00 138.97 ? 35  U   C "C2'" 1 
ATOM   6341 O "O2'" . U   C 2 35  ? 136.786 126.973 104.715 1.00 138.97 ? 35  U   C "O2'" 1 
ATOM   6342 C "C1'" . U   C 2 35  ? 137.019 129.012 103.409 1.00 138.97 ? 35  U   C "C1'" 1 
ATOM   6343 N N1    . U   C 2 35  ? 136.417 128.758 102.092 1.00 138.97 ? 35  U   C N1    1 
ATOM   6344 C C2    . U   C 2 35  ? 135.043 128.623 101.983 1.00 138.97 ? 35  U   C C2    1 
ATOM   6345 O O2    . U   C 2 35  ? 134.293 128.705 102.940 1.00 138.97 ? 35  U   C O2    1 
ATOM   6346 N N3    . U   C 2 35  ? 134.586 128.385 100.706 1.00 138.97 ? 35  U   C N3    1 
ATOM   6347 C C4    . U   C 2 35  ? 135.353 128.276 99.560  1.00 138.97 ? 35  U   C C4    1 
ATOM   6348 O O4    . U   C 2 35  ? 134.821 128.060 98.471  1.00 138.97 ? 35  U   C O4    1 
ATOM   6349 C C5    . U   C 2 35  ? 136.759 128.428 99.762  1.00 138.97 ? 35  U   C C5    1 
ATOM   6350 C C6    . U   C 2 35  ? 137.228 128.658 100.988 1.00 138.97 ? 35  U   C C6    1 
ATOM   6351 P P     . A   C 2 36  ? 139.214 129.191 107.352 1.00 115.11 ? 36  A   C P     1 
ATOM   6352 O OP1   . A   C 2 36  ? 138.555 128.796 108.623 1.00 115.11 ? 36  A   C OP1   1 
ATOM   6353 O OP2   . A   C 2 36  ? 139.650 130.599 107.169 1.00 115.11 ? 36  A   C OP2   1 
ATOM   6354 O "O5'" . A   C 2 36  ? 140.483 128.254 107.125 1.00 115.11 ? 36  A   C "O5'" 1 
ATOM   6355 C "C5'" . A   C 2 36  ? 140.647 127.052 107.863 1.00 115.11 ? 36  A   C "C5'" 1 
ATOM   6356 C "C4'" . A   C 2 36  ? 139.617 126.021 107.479 1.00 115.11 ? 36  A   C "C4'" 1 
ATOM   6357 O "O4'" . A   C 2 36  ? 139.943 125.444 106.189 1.00 115.11 ? 36  A   C "O4'" 1 
ATOM   6358 C "C3'" . A   C 2 36  ? 139.498 124.820 108.401 1.00 115.11 ? 36  A   C "C3'" 1 
ATOM   6359 O "O3'" . A   C 2 36  ? 138.722 125.102 109.554 1.00 115.11 ? 36  A   C "O3'" 1 
ATOM   6360 C "C2'" . A   C 2 36  ? 138.879 123.761 107.495 1.00 115.11 ? 36  A   C "C2'" 1 
ATOM   6361 O "O2'" . A   C 2 36  ? 137.475 123.945 107.395 1.00 115.11 ? 36  A   C "O2'" 1 
ATOM   6362 C "C1'" . A   C 2 36  ? 139.508 124.101 106.142 1.00 115.11 ? 36  A   C "C1'" 1 
ATOM   6363 N N9    . A   C 2 36  ? 140.649 123.228 105.801 1.00 115.11 ? 36  A   C N9    1 
ATOM   6364 C C8    . A   C 2 36  ? 140.595 122.064 105.074 1.00 115.11 ? 36  A   C C8    1 
ATOM   6365 N N7    . A   C 2 36  ? 141.756 121.479 104.916 1.00 115.11 ? 36  A   C N7    1 
ATOM   6366 C C5    . A   C 2 36  ? 142.639 122.314 105.584 1.00 115.11 ? 36  A   C C5    1 
ATOM   6367 C C6    . A   C 2 36  ? 144.028 122.246 105.783 1.00 115.11 ? 36  A   C C6    1 
ATOM   6368 N N6    . A   C 2 36  ? 144.794 121.261 105.308 1.00 115.11 ? 36  A   C N6    1 
ATOM   6369 N N1    . A   C 2 36  ? 144.610 123.235 106.494 1.00 115.11 ? 36  A   C N1    1 
ATOM   6370 C C2    . A   C 2 36  ? 143.838 124.220 106.968 1.00 115.11 ? 36  A   C C2    1 
ATOM   6371 N N3    . A   C 2 36  ? 142.524 124.394 106.848 1.00 115.11 ? 36  A   C N3    1 
ATOM   6372 C C4    . A   C 2 36  ? 141.973 123.394 106.138 1.00 115.11 ? 36  A   C C4    1 
ATOM   6373 P P     . G   C 2 37  ? 138.854 124.192 110.871 1.00 96.71  ? 37  G   C P     1 
ATOM   6374 O OP1   . G   C 2 37  ? 138.049 124.822 111.948 1.00 96.71  ? 37  G   C OP1   1 
ATOM   6375 O OP2   . G   C 2 37  ? 140.295 123.925 111.103 1.00 96.71  ? 37  G   C OP2   1 
ATOM   6376 O "O5'" . G   C 2 37  ? 138.138 122.829 110.462 1.00 96.71  ? 37  G   C "O5'" 1 
ATOM   6377 C "C5'" . G   C 2 37  ? 138.418 121.621 111.152 1.00 96.71  ? 37  G   C "C5'" 1 
ATOM   6378 C "C4'" . G   C 2 37  ? 139.293 120.714 110.327 1.00 96.71  ? 37  G   C "C4'" 1 
ATOM   6379 O "O4'" . G   C 2 37  ? 140.532 121.398 110.006 1.00 96.71  ? 37  G   C "O4'" 1 
ATOM   6380 C "C3'" . G   C 2 37  ? 139.740 119.428 111.003 1.00 96.71  ? 37  G   C "C3'" 1 
ATOM   6381 O "O3'" . G   C 2 37  ? 138.765 118.404 110.927 1.00 96.71  ? 37  G   C "O3'" 1 
ATOM   6382 C "C2'" . G   C 2 37  ? 141.031 119.095 110.270 1.00 96.71  ? 37  G   C "C2'" 1 
ATOM   6383 O "O2'" . G   C 2 37  ? 140.752 118.504 109.010 1.00 96.71  ? 37  G   C "O2'" 1 
ATOM   6384 C "C1'" . G   C 2 37  ? 141.609 120.487 110.031 1.00 96.71  ? 37  G   C "C1'" 1 
ATOM   6385 N N9    . G   C 2 37  ? 142.534 120.900 111.102 1.00 96.71  ? 37  G   C N9    1 
ATOM   6386 C C8    . G   C 2 37  ? 142.245 121.728 112.159 1.00 96.71  ? 37  G   C C8    1 
ATOM   6387 N N7    . G   C 2 37  ? 143.263 121.926 112.950 1.00 96.71  ? 37  G   C N7    1 
ATOM   6388 C C5    . G   C 2 37  ? 144.287 121.186 112.378 1.00 96.71  ? 37  G   C C5    1 
ATOM   6389 C C6    . G   C 2 37  ? 145.630 121.008 112.794 1.00 96.71  ? 37  G   C C6    1 
ATOM   6390 O O6    . G   C 2 37  ? 146.200 121.497 113.776 1.00 96.71  ? 37  G   C O6    1 
ATOM   6391 N N1    . G   C 2 37  ? 146.332 120.180 111.924 1.00 96.71  ? 37  G   C N1    1 
ATOM   6392 C C2    . G   C 2 37  ? 145.804 119.587 110.802 1.00 96.71  ? 37  G   C C2    1 
ATOM   6393 N N2    . G   C 2 37  ? 146.626 118.813 110.079 1.00 96.71  ? 37  G   C N2    1 
ATOM   6394 N N3    . G   C 2 37  ? 144.550 119.742 110.409 1.00 96.71  ? 37  G   C N3    1 
ATOM   6395 C C4    . G   C 2 37  ? 143.855 120.548 111.237 1.00 96.71  ? 37  G   C C4    1 
ATOM   6396 P P     . G   C 2 38  ? 138.722 117.245 112.037 1.00 94.06  ? 38  G   C P     1 
ATOM   6397 O OP1   . G   C 2 38  ? 137.475 116.464 111.835 1.00 94.06  ? 38  G   C OP1   1 
ATOM   6398 O OP2   . G   C 2 38  ? 138.995 117.864 113.359 1.00 94.06  ? 38  G   C OP2   1 
ATOM   6399 O "O5'" . G   C 2 38  ? 139.956 116.309 111.665 1.00 94.06  ? 38  G   C "O5'" 1 
ATOM   6400 C "C5'" . G   C 2 38  ? 140.015 115.644 110.412 1.00 94.06  ? 38  G   C "C5'" 1 
ATOM   6401 C "C4'" . G   C 2 38  ? 141.376 115.043 110.169 1.00 94.06  ? 38  G   C "C4'" 1 
ATOM   6402 O "O4'" . G   C 2 38  ? 142.371 116.094 110.066 1.00 94.06  ? 38  G   C "O4'" 1 
ATOM   6403 C "C3'" . G   C 2 38  ? 141.909 114.139 111.268 1.00 94.06  ? 38  G   C "C3'" 1 
ATOM   6404 O "O3'" . G   C 2 38  ? 141.376 112.828 111.207 1.00 94.06  ? 38  G   C "O3'" 1 
ATOM   6405 C "C2'" . G   C 2 38  ? 143.413 114.198 111.046 1.00 94.06  ? 38  G   C "C2'" 1 
ATOM   6406 O "O2'" . G   C 2 38  ? 143.794 113.356 109.968 1.00 94.06  ? 38  G   C "O2'" 1 
ATOM   6407 C "C1'" . G   C 2 38  ? 143.597 115.652 110.609 1.00 94.06  ? 38  G   C "C1'" 1 
ATOM   6408 N N9    . G   C 2 38  ? 143.955 116.533 111.736 1.00 94.06  ? 38  G   C N9    1 
ATOM   6409 C C8    . G   C 2 38  ? 143.123 117.411 112.383 1.00 94.06  ? 38  G   C C8    1 
ATOM   6410 N N7    . G   C 2 38  ? 143.712 118.068 113.343 1.00 94.06  ? 38  G   C N7    1 
ATOM   6411 C C5    . G   C 2 38  ? 145.015 117.595 113.330 1.00 94.06  ? 38  G   C C5    1 
ATOM   6412 C C6    . G   C 2 38  ? 146.120 117.940 114.146 1.00 94.06  ? 38  G   C C6    1 
ATOM   6413 O O6    . G   C 2 38  ? 146.170 118.755 115.073 1.00 94.06  ? 38  G   C O6    1 
ATOM   6414 N N1    . G   C 2 38  ? 147.259 117.223 113.800 1.00 94.06  ? 38  G   C N1    1 
ATOM   6415 C C2    . G   C 2 38  ? 147.326 116.292 112.793 1.00 94.06  ? 38  G   C C2    1 
ATOM   6416 N N2    . G   C 2 38  ? 148.520 115.706 112.612 1.00 94.06  ? 38  G   C N2    1 
ATOM   6417 N N3    . G   C 2 38  ? 146.302 115.962 112.021 1.00 94.06  ? 38  G   C N3    1 
ATOM   6418 C C4    . G   C 2 38  ? 145.184 116.647 112.343 1.00 94.06  ? 38  G   C C4    1 
ATOM   6419 P P     . U   C 2 39  ? 141.153 111.986 112.556 1.00 87.32  ? 39  U   C P     1 
ATOM   6420 O OP1   . U   C 2 39  ? 140.287 110.824 112.237 1.00 87.32  ? 39  U   C OP1   1 
ATOM   6421 O OP2   . U   C 2 39  ? 140.747 112.934 113.625 1.00 87.32  ? 39  U   C OP2   1 
ATOM   6422 O "O5'" . U   C 2 39  ? 142.607 111.440 112.911 1.00 87.32  ? 39  U   C "O5'" 1 
ATOM   6423 C "C5'" . U   C 2 39  ? 143.345 110.674 111.970 1.00 87.32  ? 39  U   C "C5'" 1 
ATOM   6424 C "C4'" . U   C 2 39  ? 144.801 110.588 112.350 1.00 87.32  ? 39  U   C "C4'" 1 
ATOM   6425 O "O4'" . U   C 2 39  ? 145.395 111.913 112.335 1.00 87.32  ? 39  U   C "O4'" 1 
ATOM   6426 C "C3'" . U   C 2 39  ? 145.094 110.071 113.748 1.00 87.32  ? 39  U   C "C3'" 1 
ATOM   6427 O "O3'" . U   C 2 39  ? 145.033 108.659 113.839 1.00 87.32  ? 39  U   C "O3'" 1 
ATOM   6428 C "C2'" . U   C 2 39  ? 146.476 110.646 114.030 1.00 87.32  ? 39  U   C "C2'" 1 
ATOM   6429 O "O2'" . U   C 2 39  ? 147.480 109.887 113.373 1.00 87.32  ? 39  U   C "O2'" 1 
ATOM   6430 C "C1'" . U   C 2 39  ? 146.378 112.011 113.345 1.00 87.32  ? 39  U   C "C1'" 1 
ATOM   6431 N N1    . U   C 2 39  ? 145.978 113.077 114.292 1.00 87.32  ? 39  U   C N1    1 
ATOM   6432 C C2    . U   C 2 39  ? 146.948 113.582 115.134 1.00 87.32  ? 39  U   C C2    1 
ATOM   6433 O O2    . U   C 2 39  ? 148.102 113.193 115.125 1.00 87.32  ? 39  U   C O2    1 
ATOM   6434 N N3    . U   C 2 39  ? 146.518 114.564 115.991 1.00 87.32  ? 39  U   C N3    1 
ATOM   6435 C C4    . U   C 2 39  ? 145.244 115.080 116.088 1.00 87.32  ? 39  U   C C4    1 
ATOM   6436 O O4    . U   C 2 39  ? 145.011 115.965 116.912 1.00 87.32  ? 39  U   C O4    1 
ATOM   6437 C C5    . U   C 2 39  ? 144.297 114.506 115.183 1.00 87.32  ? 39  U   C C5    1 
ATOM   6438 C C6    . U   C 2 39  ? 144.688 113.548 114.338 1.00 87.32  ? 39  U   C C6    1 
ATOM   6439 P P     . G   C 2 40  ? 144.045 107.963 114.898 1.00 82.30  ? 40  G   C P     1 
ATOM   6440 O OP1   . G   C 2 40  ? 143.733 106.596 114.410 1.00 82.30  ? 40  G   C OP1   1 
ATOM   6441 O OP2   . G   C 2 40  ? 142.939 108.911 115.187 1.00 82.30  ? 40  G   C OP2   1 
ATOM   6442 O "O5'" . G   C 2 40  ? 144.929 107.824 116.215 1.00 82.30  ? 40  G   C "O5'" 1 
ATOM   6443 C "C5'" . G   C 2 40  ? 146.074 106.985 116.238 1.00 82.30  ? 40  G   C "C5'" 1 
ATOM   6444 C "C4'" . G   C 2 40  ? 146.939 107.270 117.439 1.00 82.30  ? 40  G   C "C4'" 1 
ATOM   6445 O "O4'" . G   C 2 40  ? 147.520 108.593 117.319 1.00 82.30  ? 40  G   C "O4'" 1 
ATOM   6446 C "C3'" . G   C 2 40  ? 146.223 107.299 118.779 1.00 82.30  ? 40  G   C "C3'" 1 
ATOM   6447 O "O3'" . G   C 2 40  ? 146.024 106.006 119.322 1.00 82.30  ? 40  G   C "O3'" 1 
ATOM   6448 C "C2'" . G   C 2 40  ? 147.130 108.184 119.623 1.00 82.30  ? 40  G   C "C2'" 1 
ATOM   6449 O "O2'" . G   C 2 40  ? 148.260 107.455 120.078 1.00 82.30  ? 40  G   C "O2'" 1 
ATOM   6450 C "C1'" . G   C 2 40  ? 147.606 109.200 118.590 1.00 82.30  ? 40  G   C "C1'" 1 
ATOM   6451 N N9    . G   C 2 40  ? 146.782 110.422 118.574 1.00 82.30  ? 40  G   C N9    1 
ATOM   6452 C C8    . G   C 2 40  ? 145.706 110.679 117.762 1.00 82.30  ? 40  G   C C8    1 
ATOM   6453 N N7    . G   C 2 40  ? 145.184 111.857 117.963 1.00 82.30  ? 40  G   C N7    1 
ATOM   6454 C C5    . G   C 2 40  ? 145.967 112.410 118.965 1.00 82.30  ? 40  G   C C5    1 
ATOM   6455 C C6    . G   C 2 40  ? 145.883 113.671 119.603 1.00 82.30  ? 40  G   C C6    1 
ATOM   6456 O O6    . G   C 2 40  ? 145.079 114.588 119.404 1.00 82.30  ? 40  G   C O6    1 
ATOM   6457 N N1    . G   C 2 40  ? 146.874 113.822 120.564 1.00 82.30  ? 40  G   C N1    1 
ATOM   6458 C C2    . G   C 2 40  ? 147.827 112.889 120.875 1.00 82.30  ? 40  G   C C2    1 
ATOM   6459 N N2    . G   C 2 40  ? 148.696 113.233 121.835 1.00 82.30  ? 40  G   C N2    1 
ATOM   6460 N N3    . G   C 2 40  ? 147.916 111.707 120.289 1.00 82.30  ? 40  G   C N3    1 
ATOM   6461 C C4    . G   C 2 40  ? 146.960 111.538 119.352 1.00 82.30  ? 40  G   C C4    1 
ATOM   6462 P P     . C   C 2 41  ? 144.856 105.749 120.394 1.00 78.40  ? 41  C   C P     1 
ATOM   6463 O OP1   . C   C 2 41  ? 144.682 104.282 120.544 1.00 78.40  ? 41  C   C OP1   1 
ATOM   6464 O OP2   . C   C 2 41  ? 143.691 106.591 120.024 1.00 78.40  ? 41  C   C OP2   1 
ATOM   6465 O "O5'" . C   C 2 41  ? 145.458 106.314 121.755 1.00 78.40  ? 41  C   C "O5'" 1 
ATOM   6466 C "C5'" . C   C 2 41  ? 146.697 105.838 122.256 1.00 78.40  ? 41  C   C "C5'" 1 
ATOM   6467 C "C4'" . C   C 2 41  ? 147.216 106.725 123.357 1.00 78.40  ? 41  C   C "C4'" 1 
ATOM   6468 O "O4'" . C   C 2 41  ? 147.559 108.029 122.826 1.00 78.40  ? 41  C   C "O4'" 1 
ATOM   6469 C "C3'" . C   C 2 41  ? 146.229 107.028 124.470 1.00 78.40  ? 41  C   C "C3'" 1 
ATOM   6470 O "O3'" . C   C 2 41  ? 146.141 105.980 125.417 1.00 78.40  ? 41  C   C "O3'" 1 
ATOM   6471 C "C2'" . C   C 2 41  ? 146.762 108.333 125.046 1.00 78.40  ? 41  C   C "C2'" 1 
ATOM   6472 O "O2'" . C   C 2 41  ? 147.848 108.086 125.926 1.00 78.40  ? 41  C   C "O2'" 1 
ATOM   6473 C "C1'" . C   C 2 41  ? 147.301 109.026 123.792 1.00 78.40  ? 41  C   C "C1'" 1 
ATOM   6474 N N1    . C   C 2 41  ? 146.345 110.006 123.225 1.00 78.40  ? 41  C   C N1    1 
ATOM   6475 C C2    . C   C 2 41  ? 146.374 111.322 123.691 1.00 78.40  ? 41  C   C C2    1 
ATOM   6476 O O2    . C   C 2 41  ? 147.196 111.626 124.565 1.00 78.40  ? 41  C   C O2    1 
ATOM   6477 N N3    . C   C 2 41  ? 145.513 112.231 123.182 1.00 78.40  ? 41  C   C N3    1 
ATOM   6478 C C4    . C   C 2 41  ? 144.645 111.867 122.240 1.00 78.40  ? 41  C   C C4    1 
ATOM   6479 N N4    . C   C 2 41  ? 143.811 112.793 121.764 1.00 78.40  ? 41  C   C N4    1 
ATOM   6480 C C5    . C   C 2 41  ? 144.591 110.535 121.744 1.00 78.40  ? 41  C   C C5    1 
ATOM   6481 C C6    . C   C 2 41  ? 145.450 109.648 122.259 1.00 78.40  ? 41  C   C C6    1 
ATOM   6482 P P     . C   C 2 42  ? 144.715 105.550 126.015 1.00 76.09  ? 42  C   C P     1 
ATOM   6483 O OP1   . C   C 2 42  ? 144.834 104.166 126.540 1.00 76.09  ? 42  C   C OP1   1 
ATOM   6484 O OP2   . C   C 2 42  ? 143.669 105.872 125.011 1.00 76.09  ? 42  C   C OP2   1 
ATOM   6485 O "O5'" . C   C 2 42  ? 144.525 106.528 127.253 1.00 76.09  ? 42  C   C "O5'" 1 
ATOM   6486 C "C5'" . C   C 2 42  ? 145.606 106.786 128.134 1.00 76.09  ? 42  C   C "C5'" 1 
ATOM   6487 C "C4'" . C   C 2 42  ? 145.412 108.079 128.880 1.00 76.09  ? 42  C   C "C4'" 1 
ATOM   6488 O "O4'" . C   C 2 42  ? 145.354 109.187 127.945 1.00 76.09  ? 42  C   C "O4'" 1 
ATOM   6489 C "C3'" . C   C 2 42  ? 144.120 108.205 129.667 1.00 76.09  ? 42  C   C "C3'" 1 
ATOM   6490 O "O3'" . C   C 2 42  ? 144.161 107.532 130.912 1.00 76.09  ? 42  C   C "O3'" 1 
ATOM   6491 C "C2'" . C   C 2 42  ? 143.962 109.711 129.797 1.00 76.09  ? 42  C   C "C2'" 1 
ATOM   6492 O "O2'" . C   C 2 42  ? 144.818 110.213 130.812 1.00 76.09  ? 42  C   C "O2'" 1 
ATOM   6493 C "C1'" . C   C 2 42  ? 144.493 110.189 128.446 1.00 76.09  ? 42  C   C "C1'" 1 
ATOM   6494 N N1    . C   C 2 42  ? 143.417 110.451 127.460 1.00 76.09  ? 42  C   C N1    1 
ATOM   6495 C C2    . C   C 2 42  ? 142.727 111.666 127.531 1.00 76.09  ? 42  C   C C2    1 
ATOM   6496 O O2    . C   C 2 42  ? 143.035 112.477 128.417 1.00 76.09  ? 42  C   C O2    1 
ATOM   6497 N N3    . C   C 2 42  ? 141.753 111.946 126.634 1.00 76.09  ? 42  C   C N3    1 
ATOM   6498 C C4    . C   C 2 42  ? 141.457 111.051 125.691 1.00 76.09  ? 42  C   C C4    1 
ATOM   6499 N N4    . C   C 2 42  ? 140.489 111.353 124.824 1.00 76.09  ? 42  C   C N4    1 
ATOM   6500 C C5    . C   C 2 42  ? 142.139 109.804 125.592 1.00 76.09  ? 42  C   C C5    1 
ATOM   6501 C C6    . C   C 2 42  ? 143.104 109.547 126.485 1.00 76.09  ? 42  C   C C6    1 
ATOM   6502 P P     . U   C 2 43  ? 142.801 106.998 131.579 1.00 77.99  ? 43  U   C P     1 
ATOM   6503 O OP1   . U   C 2 43  ? 143.161 106.172 132.758 1.00 77.99  ? 43  U   C OP1   1 
ATOM   6504 O OP2   . U   C 2 43  ? 141.962 106.415 130.503 1.00 77.99  ? 43  U   C OP2   1 
ATOM   6505 O "O5'" . U   C 2 43  ? 142.084 108.322 132.098 1.00 77.99  ? 43  U   C "O5'" 1 
ATOM   6506 C "C5'" . U   C 2 43  ? 142.729 109.187 133.020 1.00 77.99  ? 43  U   C "C5'" 1 
ATOM   6507 C "C4'" . U   C 2 43  ? 142.029 110.519 133.110 1.00 77.99  ? 43  U   C "C4'" 1 
ATOM   6508 O "O4'" . U   C 2 43  ? 142.088 111.203 131.832 1.00 77.99  ? 43  U   C "O4'" 1 
ATOM   6509 C "C3'" . U   C 2 43  ? 140.546 110.460 133.425 1.00 77.99  ? 43  U   C "C3'" 1 
ATOM   6510 O "O3'" . U   C 2 43  ? 140.291 110.277 134.804 1.00 77.99  ? 43  U   C "O3'" 1 
ATOM   6511 C "C2'" . U   C 2 43  ? 140.036 111.784 132.874 1.00 77.99  ? 43  U   C "C2'" 1 
ATOM   6512 O "O2'" . U   C 2 43  ? 140.340 112.846 133.764 1.00 77.99  ? 43  U   C "O2'" 1 
ATOM   6513 C "C1'" . U   C 2 43  ? 140.903 111.942 131.625 1.00 77.99  ? 43  U   C "C1'" 1 
ATOM   6514 N N1    . U   C 2 43  ? 140.235 111.435 130.404 1.00 77.99  ? 43  U   C N1    1 
ATOM   6515 C C2    . U   C 2 43  ? 139.274 112.230 129.818 1.00 77.99  ? 43  U   C C2    1 
ATOM   6516 O O2    . U   C 2 43  ? 138.954 113.315 130.270 1.00 77.99  ? 43  U   C O2    1 
ATOM   6517 N N3    . U   C 2 43  ? 138.696 111.710 128.686 1.00 77.99  ? 43  U   C N3    1 
ATOM   6518 C C4    . U   C 2 43  ? 138.978 110.501 128.088 1.00 77.99  ? 43  U   C C4    1 
ATOM   6519 O O4    . U   C 2 43  ? 138.371 110.169 127.069 1.00 77.99  ? 43  U   C O4    1 
ATOM   6520 C C5    . U   C 2 43  ? 139.987 109.737 128.750 1.00 77.99  ? 43  U   C C5    1 
ATOM   6521 C C6    . U   C 2 43  ? 140.563 110.219 129.855 1.00 77.99  ? 43  U   C C6    1 
ATOM   6522 P P     . U   C 2 44  ? 139.290 109.120 135.286 1.00 94.94  ? 44  U   C P     1 
ATOM   6523 O OP1   . U   C 2 44  ? 139.730 108.657 136.626 1.00 94.94  ? 44  U   C OP1   1 
ATOM   6524 O OP2   . U   C 2 44  ? 139.161 108.139 134.178 1.00 94.94  ? 44  U   C OP2   1 
ATOM   6525 O "O5'" . U   C 2 44  ? 137.897 109.874 135.442 1.00 94.94  ? 44  U   C "O5'" 1 
ATOM   6526 C "C5'" . U   C 2 44  ? 137.846 111.194 135.973 1.00 94.94  ? 44  U   C "C5'" 1 
ATOM   6527 C "C4'" . U   C 2 44  ? 137.049 111.252 137.251 1.00 94.94  ? 44  U   C "C4'" 1 
ATOM   6528 O "O4'" . U   C 2 44  ? 135.644 111.045 136.947 1.00 94.94  ? 44  U   C "O4'" 1 
ATOM   6529 C "C3'" . U   C 2 44  ? 137.421 110.203 138.296 1.00 94.94  ? 44  U   C "C3'" 1 
ATOM   6530 O "O3'" . U   C 2 44  ? 137.272 110.757 139.600 1.00 94.94  ? 44  U   C "O3'" 1 
ATOM   6531 C "C2'" . U   C 2 44  ? 136.373 109.117 138.074 1.00 94.94  ? 44  U   C "C2'" 1 
ATOM   6532 O "O2'" . U   C 2 44  ? 136.119 108.307 139.202 1.00 94.94  ? 44  U   C "O2'" 1 
ATOM   6533 C "C1'" . U   C 2 44  ? 135.150 109.942 137.682 1.00 94.94  ? 44  U   C "C1'" 1 
ATOM   6534 N N1    . U   C 2 44  ? 134.196 109.223 136.826 1.00 94.94  ? 44  U   C N1    1 
ATOM   6535 C C2    . U   C 2 44  ? 132.975 108.874 137.366 1.00 94.94  ? 44  U   C C2    1 
ATOM   6536 O O2    . U   C 2 44  ? 132.659 109.131 138.514 1.00 94.94  ? 44  U   C O2    1 
ATOM   6537 N N3    . U   C 2 44  ? 132.136 108.208 136.509 1.00 94.94  ? 44  U   C N3    1 
ATOM   6538 C C4    . U   C 2 44  ? 132.390 107.866 135.197 1.00 94.94  ? 44  U   C C4    1 
ATOM   6539 O O4    . U   C 2 44  ? 131.530 107.265 134.553 1.00 94.94  ? 44  U   C O4    1 
ATOM   6540 C C5    . U   C 2 44  ? 133.675 108.266 134.713 1.00 94.94  ? 44  U   C C5    1 
ATOM   6541 C C6    . U   C 2 44  ? 134.513 108.916 135.525 1.00 94.94  ? 44  U   C C6    1 
ATOM   6542 P P     . U   C 2 45  ? 138.551 110.893 140.561 1.00 72.96  ? 45  U   C P     1 
ATOM   6543 O OP1   . U   C 2 45  ? 138.187 111.770 141.702 1.00 72.96  ? 45  U   C OP1   1 
ATOM   6544 O OP2   . U   C 2 45  ? 139.723 111.240 139.720 1.00 72.96  ? 45  U   C OP2   1 
ATOM   6545 O "O5'" . U   C 2 45  ? 138.762 109.417 141.119 1.00 72.96  ? 45  U   C "O5'" 1 
ATOM   6546 C "C5'" . U   C 2 45  ? 137.816 108.834 142.001 1.00 72.96  ? 45  U   C "C5'" 1 
ATOM   6547 C "C4'" . U   C 2 45  ? 138.482 107.915 142.993 1.00 72.96  ? 45  U   C "C4'" 1 
ATOM   6548 O "O4'" . U   C 2 45  ? 139.881 108.271 143.115 1.00 72.96  ? 45  U   C "O4'" 1 
ATOM   6549 C "C3'" . U   C 2 45  ? 137.951 107.978 144.418 1.00 72.96  ? 45  U   C "C3'" 1 
ATOM   6550 O "O3'" . U   C 2 45  ? 136.791 107.184 144.606 1.00 72.96  ? 45  U   C "O3'" 1 
ATOM   6551 C "C2'" . U   C 2 45  ? 139.143 107.514 145.249 1.00 72.96  ? 45  U   C "C2'" 1 
ATOM   6552 O "O2'" . U   C 2 45  ? 139.211 106.097 145.279 1.00 72.96  ? 45  U   C "O2'" 1 
ATOM   6553 C "C1'" . U   C 2 45  ? 140.326 108.036 144.431 1.00 72.96  ? 45  U   C "C1'" 1 
ATOM   6554 N N1    . U   C 2 45  ? 140.934 109.273 144.981 1.00 72.96  ? 45  U   C N1    1 
ATOM   6555 C C2    . U   C 2 45  ? 140.363 110.520 144.781 1.00 72.96  ? 45  U   C C2    1 
ATOM   6556 O O2    . U   C 2 45  ? 139.339 110.722 144.156 1.00 72.96  ? 45  U   C O2    1 
ATOM   6557 N N3    . U   C 2 45  ? 141.048 111.566 145.346 1.00 72.96  ? 45  U   C N3    1 
ATOM   6558 C C4    . U   C 2 45  ? 142.213 111.510 146.076 1.00 72.96  ? 45  U   C C4    1 
ATOM   6559 O O4    . U   C 2 45  ? 142.703 112.548 146.520 1.00 72.96  ? 45  U   C O4    1 
ATOM   6560 C C5    . U   C 2 45  ? 142.739 110.195 146.239 1.00 72.96  ? 45  U   C C5    1 
ATOM   6561 C C6    . U   C 2 45  ? 142.097 109.158 145.699 1.00 72.96  ? 45  U   C C6    1 
ATOM   6562 P P     . G   C 2 46  ? 135.334 107.851 144.839 1.00 76.22  ? 46  G   C P     1 
ATOM   6563 O OP1   . G   C 2 46  ? 134.435 106.841 145.519 1.00 76.22  ? 46  G   C OP1   1 
ATOM   6564 O OP2   . G   C 2 46  ? 134.807 108.381 143.519 1.00 76.22  ? 46  G   C OP2   1 
ATOM   6565 O "O5'" . G   C 2 46  ? 135.592 109.086 145.851 1.00 76.22  ? 46  G   C "O5'" 1 
ATOM   6566 C "C5'" . G   C 2 46  ? 134.897 109.107 147.122 1.00 76.22  ? 46  G   C "C5'" 1 
ATOM   6567 C "C4'" . G   C 2 46  ? 135.752 108.430 148.164 1.00 76.22  ? 46  G   C "C4'" 1 
ATOM   6568 O "O4'" . G   C 2 46  ? 137.136 108.479 147.740 1.00 76.22  ? 46  G   C "O4'" 1 
ATOM   6569 C "C3'" . G   C 2 46  ? 135.739 109.062 149.560 1.00 76.22  ? 46  G   C "C3'" 1 
ATOM   6570 O "O3'" . G   C 2 46  ? 134.721 108.498 150.373 1.00 76.22  ? 46  G   C "O3'" 1 
ATOM   6571 C "C2'" . G   C 2 46  ? 137.127 108.704 150.091 1.00 76.22  ? 46  G   C "C2'" 1 
ATOM   6572 O "O2'" . G   C 2 46  ? 137.170 107.406 150.639 1.00 76.22  ? 46  G   C "O2'" 1 
ATOM   6573 C "C1'" . G   C 2 46  ? 137.975 108.799 148.827 1.00 76.22  ? 46  G   C "C1'" 1 
ATOM   6574 N N9    . G   C 2 46  ? 138.537 110.122 148.597 1.00 76.22  ? 46  G   C N9    1 
ATOM   6575 C C8    . G   C 2 46  ? 138.122 111.052 147.678 1.00 76.22  ? 46  G   C C8    1 
ATOM   6576 N N7    . G   C 2 46  ? 138.827 112.156 147.705 1.00 76.22  ? 46  G   C N7    1 
ATOM   6577 C C5    . G   C 2 46  ? 139.767 111.933 148.700 1.00 76.22  ? 46  G   C C5    1 
ATOM   6578 C C6    . G   C 2 46  ? 140.797 112.774 149.178 1.00 76.22  ? 46  G   C C6    1 
ATOM   6579 O O6    . G   C 2 46  ? 141.088 113.916 148.799 1.00 76.22  ? 46  G   C O6    1 
ATOM   6580 N N1    . G   C 2 46  ? 141.516 112.161 150.202 1.00 76.22  ? 46  G   C N1    1 
ATOM   6581 C C2    . G   C 2 46  ? 141.282 110.901 150.694 1.00 76.22  ? 46  G   C C2    1 
ATOM   6582 N N2    . G   C 2 46  ? 142.085 110.481 151.679 1.00 76.22  ? 46  G   C N2    1 
ATOM   6583 N N3    . G   C 2 46  ? 140.313 110.107 150.250 1.00 76.22  ? 46  G   C N3    1 
ATOM   6584 C C4    . G   C 2 46  ? 139.599 110.687 149.258 1.00 76.22  ? 46  G   C C4    1 
ATOM   6585 P P     . A   C 2 47  ? 133.752 109.455 151.194 1.00 90.97  ? 47  A   C P     1 
ATOM   6586 O OP1   . A   C 2 47  ? 132.581 108.658 151.631 1.00 90.97  ? 47  A   C OP1   1 
ATOM   6587 O OP2   . A   C 2 47  ? 133.546 110.691 150.399 1.00 90.97  ? 47  A   C OP2   1 
ATOM   6588 O "O5'" . A   C 2 47  ? 134.624 109.829 152.472 1.00 90.97  ? 47  A   C "O5'" 1 
ATOM   6589 C "C5'" . A   C 2 47  ? 134.772 111.199 152.879 1.00 90.97  ? 47  A   C "C5'" 1 
ATOM   6590 C "C4'" . A   C 2 47  ? 135.829 111.309 153.948 1.00 90.97  ? 47  A   C "C4'" 1 
ATOM   6591 O "O4'" . A   C 2 47  ? 137.132 111.054 153.353 1.00 90.97  ? 47  A   C "O4'" 1 
ATOM   6592 C "C3'" . A   C 2 47  ? 135.950 112.682 154.604 1.00 90.97  ? 47  A   C "C3'" 1 
ATOM   6593 O "O3'" . A   C 2 47  ? 135.094 112.809 155.733 1.00 90.97  ? 47  A   C "O3'" 1 
ATOM   6594 C "C2'" . A   C 2 47  ? 137.421 112.722 154.988 1.00 90.97  ? 47  A   C "C2'" 1 
ATOM   6595 O "O2'" . A   C 2 47  ? 137.713 112.011 156.173 1.00 90.97  ? 47  A   C "O2'" 1 
ATOM   6596 C "C1'" . A   C 2 47  ? 138.054 112.041 153.778 1.00 90.97  ? 47  A   C "C1'" 1 
ATOM   6597 N N9    . A   C 2 47  ? 138.269 112.965 152.667 1.00 90.97  ? 47  A   C N9    1 
ATOM   6598 C C8    . A   C 2 47  ? 137.692 112.933 151.423 1.00 90.97  ? 47  A   C C8    1 
ATOM   6599 N N7    . A   C 2 47  ? 138.077 113.908 150.636 1.00 90.97  ? 47  A   C N7    1 
ATOM   6600 C C5    . A   C 2 47  ? 138.970 114.630 151.414 1.00 90.97  ? 47  A   C C5    1 
ATOM   6601 C C6    . A   C 2 47  ? 139.732 115.781 151.156 1.00 90.97  ? 47  A   C C6    1 
ATOM   6602 N N6    . A   C 2 47  ? 139.709 116.438 149.995 1.00 90.97  ? 47  A   C N6    1 
ATOM   6603 N N1    . A   C 2 47  ? 140.519 116.248 152.148 1.00 90.97  ? 47  A   C N1    1 
ATOM   6604 C C2    . A   C 2 47  ? 140.539 115.590 153.312 1.00 90.97  ? 47  A   C C2    1 
ATOM   6605 N N3    . A   C 2 47  ? 139.873 114.498 153.675 1.00 90.97  ? 47  A   C N3    1 
ATOM   6606 C C4    . A   C 2 47  ? 139.097 114.062 152.668 1.00 90.97  ? 47  A   C C4    1 
ATOM   6607 P P     . G   C 2 48  ? 133.883 113.851 155.692 1.00 92.48  ? 48  G   C P     1 
ATOM   6608 O OP1   . G   C 2 48  ? 132.646 113.199 156.276 1.00 92.48  ? 48  G   C OP1   1 
ATOM   6609 O OP2   . G   C 2 48  ? 133.735 114.384 154.281 1.00 92.48  ? 48  G   C OP2   1 
ATOM   6610 O "O5'" . G   C 2 48  ? 134.367 115.047 156.651 1.00 92.48  ? 48  G   C "O5'" 1 
ATOM   6611 C "C5'" . G   C 2 48  ? 135.125 114.716 157.835 1.00 92.48  ? 48  G   C "C5'" 1 
ATOM   6612 C "C4'" . G   C 2 48  ? 136.229 115.726 158.009 1.00 92.48  ? 48  G   C "C4'" 1 
ATOM   6613 O "O4'" . G   C 2 48  ? 137.220 115.533 156.969 1.00 92.48  ? 48  G   C "O4'" 1 
ATOM   6614 C "C3'" . G   C 2 48  ? 135.831 117.194 157.844 1.00 92.48  ? 48  G   C "C3'" 1 
ATOM   6615 O "O3'" . G   C 2 48  ? 135.221 117.753 158.998 1.00 92.48  ? 48  G   C "O3'" 1 
ATOM   6616 C "C2'" . G   C 2 48  ? 137.189 117.832 157.549 1.00 92.48  ? 48  G   C "C2'" 1 
ATOM   6617 O "O2'" . G   C 2 48  ? 137.944 118.104 158.709 1.00 92.48  ? 48  G   C "O2'" 1 
ATOM   6618 C "C1'" . G   C 2 48  ? 137.841 116.765 156.674 1.00 92.48  ? 48  G   C "C1'" 1 
ATOM   6619 N N9    . G   C 2 48  ? 137.687 117.045 155.254 1.00 92.48  ? 48  G   C N9    1 
ATOM   6620 C C8    . G   C 2 48  ? 136.901 116.378 154.350 1.00 92.48  ? 48  G   C C8    1 
ATOM   6621 N N7    . G   C 2 48  ? 136.965 116.882 153.143 1.00 92.48  ? 48  G   C N7    1 
ATOM   6622 C C5    . G   C 2 48  ? 137.837 117.956 153.266 1.00 92.48  ? 48  G   C C5    1 
ATOM   6623 C C6    . G   C 2 48  ? 138.292 118.874 152.292 1.00 92.48  ? 48  G   C C6    1 
ATOM   6624 O O6    . G   C 2 48  ? 137.999 118.925 151.090 1.00 92.48  ? 48  G   C O6    1 
ATOM   6625 N N1    . G   C 2 48  ? 139.174 119.803 152.843 1.00 92.48  ? 48  G   C N1    1 
ATOM   6626 C C2    . G   C 2 48  ? 139.568 119.841 154.157 1.00 92.48  ? 48  G   C C2    1 
ATOM   6627 N N2    . G   C 2 48  ? 140.419 120.815 154.503 1.00 92.48  ? 48  G   C N2    1 
ATOM   6628 N N3    . G   C 2 48  ? 139.145 118.978 155.076 1.00 92.48  ? 48  G   C N3    1 
ATOM   6629 C C4    . G   C 2 48  ? 138.286 118.068 154.561 1.00 92.48  ? 48  G   C C4    1 
ATOM   6630 P P     . A   C 2 49  ? 134.071 118.841 158.825 1.00 95.42  ? 49  A   C P     1 
ATOM   6631 O OP1   . A   C 2 49  ? 133.274 118.869 160.075 1.00 95.42  ? 49  A   C OP1   1 
ATOM   6632 O OP2   . A   C 2 49  ? 133.398 118.594 157.527 1.00 95.42  ? 49  A   C OP2   1 
ATOM   6633 O "O5'" . A   C 2 49  ? 134.882 120.205 158.713 1.00 95.42  ? 49  A   C "O5'" 1 
ATOM   6634 C "C5'" . A   C 2 49  ? 135.420 120.827 159.889 1.00 95.42  ? 49  A   C "C5'" 1 
ATOM   6635 C "C4'" . A   C 2 49  ? 136.309 121.980 159.502 1.00 95.42  ? 49  A   C "C4'" 1 
ATOM   6636 O "O4'" . A   C 2 49  ? 137.302 121.516 158.549 1.00 95.42  ? 49  A   C "O4'" 1 
ATOM   6637 C "C3'" . A   C 2 49  ? 135.624 123.144 158.792 1.00 95.42  ? 49  A   C "C3'" 1 
ATOM   6638 O "O3'" . A   C 2 49  ? 134.987 124.045 159.706 1.00 95.42  ? 49  A   C "O3'" 1 
ATOM   6639 C "C2'" . A   C 2 49  ? 136.796 123.778 158.054 1.00 95.42  ? 49  A   C "C2'" 1 
ATOM   6640 O "O2'" . A   C 2 49  ? 137.591 124.597 158.884 1.00 95.42  ? 49  A   C "O2'" 1 
ATOM   6641 C "C1'" . A   C 2 49  ? 137.579 122.541 157.610 1.00 95.42  ? 49  A   C "C1'" 1 
ATOM   6642 N N9    . A   C 2 49  ? 137.166 122.077 156.287 1.00 95.42  ? 49  A   C N9    1 
ATOM   6643 C C8    . A   C 2 49  ? 136.350 121.018 155.976 1.00 95.42  ? 49  A   C C8    1 
ATOM   6644 N N7    . A   C 2 49  ? 136.140 120.872 154.690 1.00 95.42  ? 49  A   C N7    1 
ATOM   6645 C C5    . A   C 2 49  ? 136.865 121.906 154.116 1.00 95.42  ? 49  A   C C5    1 
ATOM   6646 C C6    . A   C 2 49  ? 137.046 122.306 152.782 1.00 95.42  ? 49  A   C C6    1 
ATOM   6647 N N6    . A   C 2 49  ? 136.505 121.672 151.739 1.00 95.42  ? 49  A   C N6    1 
ATOM   6648 N N1    . A   C 2 49  ? 137.820 123.388 152.550 1.00 95.42  ? 49  A   C N1    1 
ATOM   6649 C C2    . A   C 2 49  ? 138.372 124.016 153.595 1.00 95.42  ? 49  A   C C2    1 
ATOM   6650 N N3    . A   C 2 49  ? 138.274 123.738 154.893 1.00 95.42  ? 49  A   C N3    1 
ATOM   6651 C C4    . A   C 2 49  ? 137.498 122.659 155.088 1.00 95.42  ? 49  A   C C4    1 
ATOM   6652 P P     . G   C 2 50  ? 133.552 124.747 159.359 1.00 97.16  ? 50  G   C P     1 
ATOM   6653 O OP1   . G   C 2 50  ? 133.024 125.337 160.614 1.00 97.16  ? 50  G   C OP1   1 
ATOM   6654 O OP2   . G   C 2 50  ? 132.722 123.778 158.600 1.00 97.16  ? 50  G   C OP2   1 
ATOM   6655 O "O5'" . G   C 2 50  ? 133.938 125.939 158.378 1.00 97.16  ? 50  G   C "O5'" 1 
ATOM   6656 C "C5'" . G   C 2 50  ? 134.921 126.898 158.742 1.00 97.16  ? 50  G   C "C5'" 1 
ATOM   6657 C "C4'" . G   C 2 50  ? 135.339 127.716 157.548 1.00 97.16  ? 50  G   C "C4'" 1 
ATOM   6658 O "O4'" . G   C 2 50  ? 136.086 126.882 156.631 1.00 97.16  ? 50  G   C "O4'" 1 
ATOM   6659 C "C3'" . G   C 2 50  ? 134.195 128.270 156.713 1.00 97.16  ? 50  G   C "C3'" 1 
ATOM   6660 O "O3'" . G   C 2 50  ? 133.697 129.489 157.234 1.00 97.16  ? 50  G   C "O3'" 1 
ATOM   6661 C "C2'" . G   C 2 50  ? 134.808 128.406 155.324 1.00 97.16  ? 50  G   C "C2'" 1 
ATOM   6662 O "O2'" . G   C 2 50  ? 135.544 129.612 155.209 1.00 97.16  ? 50  G   C "O2'" 1 
ATOM   6663 C "C1'" . G   C 2 50  ? 135.796 127.241 155.299 1.00 97.16  ? 50  G   C "C1'" 1 
ATOM   6664 N N9    . G   C 2 50  ? 135.286 126.054 154.592 1.00 97.16  ? 50  G   C N9    1 
ATOM   6665 C C8    . G   C 2 50  ? 135.098 124.812 155.140 1.00 97.16  ? 50  G   C C8    1 
ATOM   6666 N N7    . G   C 2 50  ? 134.664 123.931 154.286 1.00 97.16  ? 50  G   C N7    1 
ATOM   6667 C C5    . G   C 2 50  ? 134.566 124.634 153.097 1.00 97.16  ? 50  G   C C5    1 
ATOM   6668 C C6    . G   C 2 50  ? 134.146 124.198 151.819 1.00 97.16  ? 50  G   C C6    1 
ATOM   6669 O O6    . G   C 2 50  ? 133.769 123.070 151.482 1.00 97.16  ? 50  G   C O6    1 
ATOM   6670 N N1    . G   C 2 50  ? 134.197 125.230 150.890 1.00 97.16  ? 50  G   C N1    1 
ATOM   6671 C C2    . G   C 2 50  ? 134.599 126.518 151.155 1.00 97.16  ? 50  G   C C2    1 
ATOM   6672 N N2    . G   C 2 50  ? 134.582 127.379 150.128 1.00 97.16  ? 50  G   C N2    1 
ATOM   6673 N N3    . G   C 2 50  ? 134.995 126.934 152.346 1.00 97.16  ? 50  G   C N3    1 
ATOM   6674 C C4    . G   C 2 50  ? 134.953 125.946 153.263 1.00 97.16  ? 50  G   C C4    1 
ATOM   6675 P P     . U   C 2 51  ? 132.116 129.734 157.359 1.00 101.41 ? 51  U   C P     1 
ATOM   6676 O OP1   . U   C 2 51  ? 131.907 130.916 158.232 1.00 101.41 ? 51  U   C OP1   1 
ATOM   6677 O OP2   . U   C 2 51  ? 131.471 128.442 157.704 1.00 101.41 ? 51  U   C OP2   1 
ATOM   6678 O "O5'" . U   C 2 51  ? 131.678 130.123 155.879 1.00 101.41 ? 51  U   C "O5'" 1 
ATOM   6679 C "C5'" . U   C 2 51  ? 132.384 131.113 155.146 1.00 101.41 ? 51  U   C "C5'" 1 
ATOM   6680 C "C4'" . U   C 2 51  ? 132.048 131.041 153.680 1.00 101.41 ? 51  U   C "C4'" 1 
ATOM   6681 O "O4'" . U   C 2 51  ? 132.661 129.866 153.095 1.00 101.41 ? 51  U   C "O4'" 1 
ATOM   6682 C "C3'" . U   C 2 51  ? 130.571 130.891 153.359 1.00 101.41 ? 51  U   C "C3'" 1 
ATOM   6683 O "O3'" . U   C 2 51  ? 129.889 132.132 153.377 1.00 101.41 ? 51  U   C "O3'" 1 
ATOM   6684 C "C2'" . U   C 2 51  ? 130.584 130.220 151.991 1.00 101.41 ? 51  U   C "C2'" 1 
ATOM   6685 O "O2'" . U   C 2 51  ? 130.804 131.175 150.964 1.00 101.41 ? 51  U   C "O2'" 1 
ATOM   6686 C "C1'" . U   C 2 51  ? 131.824 129.330 152.093 1.00 101.41 ? 51  U   C "C1'" 1 
ATOM   6687 N N1    . U   C 2 51  ? 131.505 127.928 152.445 1.00 101.41 ? 51  U   C N1    1 
ATOM   6688 C C2    . U   C 2 51  ? 131.171 127.068 151.418 1.00 101.41 ? 51  U   C C2    1 
ATOM   6689 O O2    . U   C 2 51  ? 131.112 127.420 150.253 1.00 101.41 ? 51  U   C O2    1 
ATOM   6690 N N3    . U   C 2 51  ? 130.903 125.779 151.806 1.00 101.41 ? 51  U   C N3    1 
ATOM   6691 C C4    . U   C 2 51  ? 130.940 125.271 153.087 1.00 101.41 ? 51  U   C C4    1 
ATOM   6692 O O4    . U   C 2 51  ? 130.671 124.084 153.275 1.00 101.41 ? 51  U   C O4    1 
ATOM   6693 C C5    . U   C 2 51  ? 131.300 126.222 154.092 1.00 101.41 ? 51  U   C C5    1 
ATOM   6694 C C6    . U   C 2 51  ? 131.568 127.484 153.745 1.00 101.41 ? 51  U   C C6    1 
ATOM   6695 P P     . U   C 2 52  ? 128.842 132.465 154.547 1.00 107.45 ? 52  U   C P     1 
ATOM   6696 O OP1   . U   C 2 52  ? 129.237 133.758 155.158 1.00 107.45 ? 52  U   C OP1   1 
ATOM   6697 O OP2   . U   C 2 52  ? 128.709 131.264 155.409 1.00 107.45 ? 52  U   C OP2   1 
ATOM   6698 O "O5'" . U   C 2 52  ? 127.468 132.663 153.770 1.00 107.45 ? 52  U   C "O5'" 1 
ATOM   6699 C "C5'" . U   C 2 52  ? 127.037 131.702 152.814 1.00 107.45 ? 52  U   C "C5'" 1 
ATOM   6700 C "C4'" . U   C 2 52  ? 125.700 132.060 152.219 1.00 107.45 ? 52  U   C "C4'" 1 
ATOM   6701 O "O4'" . U   C 2 52  ? 125.212 130.916 151.469 1.00 107.45 ? 52  U   C "O4'" 1 
ATOM   6702 C "C3'" . U   C 2 52  ? 124.613 132.395 153.234 1.00 107.45 ? 52  U   C "C3'" 1 
ATOM   6703 O "O3'" . U   C 2 52  ? 123.710 133.348 152.675 1.00 107.45 ? 52  U   C "O3'" 1 
ATOM   6704 C "C2'" . U   C 2 52  ? 123.905 131.059 153.421 1.00 107.45 ? 52  U   C "C2'" 1 
ATOM   6705 O "O2'" . U   C 2 52  ? 122.569 131.160 153.866 1.00 107.45 ? 52  U   C "O2'" 1 
ATOM   6706 C "C1'" . U   C 2 52  ? 123.991 130.459 152.020 1.00 107.45 ? 52  U   C "C1'" 1 
ATOM   6707 N N1    . U   C 2 52  ? 124.031 128.992 152.023 1.00 107.45 ? 52  U   C N1    1 
ATOM   6708 C C2    . U   C 2 52  ? 123.028 128.304 151.374 1.00 107.45 ? 52  U   C C2    1 
ATOM   6709 O O2    . U   C 2 52  ? 122.112 128.859 150.792 1.00 107.45 ? 52  U   C O2    1 
ATOM   6710 N N3    . U   C 2 52  ? 123.142 126.938 151.429 1.00 107.45 ? 52  U   C N3    1 
ATOM   6711 C C4    . U   C 2 52  ? 124.133 126.214 152.058 1.00 107.45 ? 52  U   C C4    1 
ATOM   6712 O O4    . U   C 2 52  ? 124.100 124.984 152.021 1.00 107.45 ? 52  U   C O4    1 
ATOM   6713 C C5    . U   C 2 52  ? 125.133 127.002 152.709 1.00 107.45 ? 52  U   C C5    1 
ATOM   6714 C C6    . U   C 2 52  ? 125.047 128.332 152.669 1.00 107.45 ? 52  U   C C6    1 
ATOM   6715 P P     . A   C 2 53  ? 123.325 134.665 153.509 1.00 131.45 ? 53  A   C P     1 
ATOM   6716 O OP1   . A   C 2 53  ? 121.882 134.586 153.853 1.00 131.45 ? 53  A   C OP1   1 
ATOM   6717 O OP2   . A   C 2 53  ? 123.834 135.844 152.763 1.00 131.45 ? 53  A   C OP2   1 
ATOM   6718 O "O5'" . A   C 2 53  ? 124.178 134.527 154.847 1.00 131.45 ? 53  A   C "O5'" 1 
ATOM   6719 C "C5'" . A   C 2 53  ? 123.593 134.749 156.121 1.00 131.45 ? 53  A   C "C5'" 1 
ATOM   6720 C "C4'" . A   C 2 53  ? 122.948 133.495 156.655 1.00 131.45 ? 53  A   C "C4'" 1 
ATOM   6721 O "O4'" . A   C 2 53  ? 123.860 132.374 156.528 1.00 131.45 ? 53  A   C "O4'" 1 
ATOM   6722 C "C3'" . A   C 2 53  ? 122.581 133.501 158.129 1.00 131.45 ? 53  A   C "C3'" 1 
ATOM   6723 O "O3'" . A   C 2 53  ? 121.377 134.194 158.402 1.00 131.45 ? 53  A   C "O3'" 1 
ATOM   6724 C "C2'" . A   C 2 53  ? 122.518 132.014 158.457 1.00 131.45 ? 53  A   C "C2'" 1 
ATOM   6725 O "O2'" . A   C 2 53  ? 121.293 131.453 158.011 1.00 131.45 ? 53  A   C "O2'" 1 
ATOM   6726 C "C1'" . A   C 2 53  ? 123.648 131.462 157.586 1.00 131.45 ? 53  A   C "C1'" 1 
ATOM   6727 N N9    . A   C 2 53  ? 124.904 131.297 158.341 1.00 131.45 ? 53  A   C N9    1 
ATOM   6728 C C8    . A   C 2 53  ? 125.498 132.175 159.213 1.00 131.45 ? 53  A   C C8    1 
ATOM   6729 N N7    . A   C 2 53  ? 126.618 131.733 159.731 1.00 131.45 ? 53  A   C N7    1 
ATOM   6730 C C5    . A   C 2 53  ? 126.773 130.477 159.161 1.00 131.45 ? 53  A   C C5    1 
ATOM   6731 C C6    . A   C 2 53  ? 127.765 129.490 159.300 1.00 131.45 ? 53  A   C C6    1 
ATOM   6732 N N6    . A   C 2 53  ? 128.833 129.620 160.089 1.00 131.45 ? 53  A   C N6    1 
ATOM   6733 N N1    . A   C 2 53  ? 127.620 128.350 158.590 1.00 131.45 ? 53  A   C N1    1 
ATOM   6734 C C2    . A   C 2 53  ? 126.549 128.219 157.798 1.00 131.45 ? 53  A   C C2    1 
ATOM   6735 N N3    . A   C 2 53  ? 125.551 129.074 157.585 1.00 131.45 ? 53  A   C N3    1 
ATOM   6736 C C4    . A   C 2 53  ? 125.726 130.196 158.303 1.00 131.45 ? 53  A   C C4    1 
ATOM   6737 P P     . C   C 2 54  ? 121.053 134.686 159.898 1.00 161.00 ? 54  C   C P     1 
ATOM   6738 O OP1   . C   C 2 54  ? 119.837 135.536 159.846 1.00 161.00 ? 54  C   C OP1   1 
ATOM   6739 O OP2   . C   C 2 54  ? 122.305 135.226 160.486 1.00 161.00 ? 54  C   C OP2   1 
ATOM   6740 O "O5'" . C   C 2 54  ? 120.681 133.343 160.670 1.00 161.00 ? 54  C   C "O5'" 1 
ATOM   6741 C "C5'" . C   C 2 54  ? 121.334 132.983 161.880 1.00 161.00 ? 54  C   C "C5'" 1 
ATOM   6742 C "C4'" . C   C 2 54  ? 120.894 131.620 162.353 1.00 161.00 ? 54  C   C "C4'" 1 
ATOM   6743 O "O4'" . C   C 2 54  ? 119.449 131.531 162.276 1.00 161.00 ? 54  C   C "O4'" 1 
ATOM   6744 C "C3'" . C   C 2 54  ? 121.386 130.439 161.529 1.00 161.00 ? 54  C   C "C3'" 1 
ATOM   6745 O "O3'" . C   C 2 54  ? 122.697 130.032 161.883 1.00 161.00 ? 54  C   C "O3'" 1 
ATOM   6746 C "C2'" . C   C 2 54  ? 120.325 129.377 161.787 1.00 161.00 ? 54  C   C "C2'" 1 
ATOM   6747 O "O2'" . C   C 2 54  ? 120.551 128.736 163.034 1.00 161.00 ? 54  C   C "O2'" 1 
ATOM   6748 C "C1'" . C   C 2 54  ? 119.060 130.227 161.904 1.00 161.00 ? 54  C   C "C1'" 1 
ATOM   6749 N N1    . C   C 2 54  ? 118.298 130.305 160.635 1.00 161.00 ? 54  C   C N1    1 
ATOM   6750 C C2    . C   C 2 54  ? 117.285 129.372 160.399 1.00 161.00 ? 54  C   C C2    1 
ATOM   6751 O O2    . C   C 2 54  ? 117.065 128.500 161.254 1.00 161.00 ? 54  C   C O2    1 
ATOM   6752 N N3    . C   C 2 54  ? 116.573 129.442 159.248 1.00 161.00 ? 54  C   C N3    1 
ATOM   6753 C C4    . C   C 2 54  ? 116.841 130.398 158.355 1.00 161.00 ? 54  C   C C4    1 
ATOM   6754 N N4    . C   C 2 54  ? 116.119 130.432 157.233 1.00 161.00 ? 54  C   C N4    1 
ATOM   6755 C C5    . C   C 2 54  ? 117.865 131.363 158.570 1.00 161.00 ? 54  C   C C5    1 
ATOM   6756 C C6    . C   C 2 54  ? 118.557 131.281 159.711 1.00 161.00 ? 54  C   C C6    1 
ATOM   6757 P P     . U   C 2 55  ? 123.381 128.769 161.161 1.00 162.33 ? 55  U   C P     1 
ATOM   6758 O OP1   . U   C 2 55  ? 124.851 128.882 161.337 1.00 162.33 ? 55  U   C OP1   1 
ATOM   6759 O OP2   . U   C 2 55  ? 122.814 128.654 159.794 1.00 162.33 ? 55  U   C OP2   1 
ATOM   6760 O "O5'" . U   C 2 55  ? 122.882 127.518 162.013 1.00 162.33 ? 55  U   C "O5'" 1 
ATOM   6761 C "C5'" . U   C 2 55  ? 123.136 126.192 161.573 1.00 162.33 ? 55  U   C "C5'" 1 
ATOM   6762 C "C4'" . U   C 2 55  ? 121.975 125.276 161.869 1.00 162.33 ? 55  U   C "C4'" 1 
ATOM   6763 O "O4'" . U   C 2 55  ? 120.726 125.990 161.683 1.00 162.33 ? 55  U   C "O4'" 1 
ATOM   6764 C "C3'" . U   C 2 55  ? 121.854 124.055 160.969 1.00 162.33 ? 55  U   C "C3'" 1 
ATOM   6765 O "O3'" . U   C 2 55  ? 122.683 122.986 161.396 1.00 162.33 ? 55  U   C "O3'" 1 
ATOM   6766 C "C2'" . U   C 2 55  ? 120.366 123.732 161.027 1.00 162.33 ? 55  U   C "C2'" 1 
ATOM   6767 O "O2'" . U   C 2 55  ? 120.056 123.000 162.204 1.00 162.33 ? 55  U   C "O2'" 1 
ATOM   6768 C "C1'" . U   C 2 55  ? 119.746 125.126 161.148 1.00 162.33 ? 55  U   C "C1'" 1 
ATOM   6769 N N1    . U   C 2 55  ? 119.289 125.689 159.854 1.00 162.33 ? 55  U   C N1    1 
ATOM   6770 C C2    . U   C 2 55  ? 118.309 125.061 159.096 1.00 162.33 ? 55  U   C C2    1 
ATOM   6771 O O2    . U   C 2 55  ? 117.780 124.005 159.403 1.00 162.33 ? 55  U   C O2    1 
ATOM   6772 N N3    . U   C 2 55  ? 117.978 125.713 157.929 1.00 162.33 ? 55  U   C N3    1 
ATOM   6773 C C4    . U   C 2 55  ? 118.496 126.905 157.462 1.00 162.33 ? 55  U   C C4    1 
ATOM   6774 O O4    . U   C 2 55  ? 118.106 127.385 156.397 1.00 162.33 ? 55  U   C O4    1 
ATOM   6775 C C5    . U   C 2 55  ? 119.484 127.494 158.306 1.00 162.33 ? 55  U   C C5    1 
ATOM   6776 C C6    . U   C 2 55  ? 119.828 126.882 159.439 1.00 162.33 ? 55  U   C C6    1 
ATOM   6777 P P     . C   C 2 56  ? 122.887 121.683 160.476 1.00 165.90 ? 56  C   C P     1 
ATOM   6778 O OP1   . C   C 2 56  ? 123.996 120.883 161.054 1.00 165.90 ? 56  C   C OP1   1 
ATOM   6779 O OP2   . C   C 2 56  ? 122.963 122.128 159.061 1.00 165.90 ? 56  C   C OP2   1 
ATOM   6780 O "O5'" . C   C 2 56  ? 121.539 120.857 160.667 1.00 165.90 ? 56  C   C "O5'" 1 
ATOM   6781 C "C5'" . C   C 2 56  ? 121.554 119.443 160.797 1.00 165.90 ? 56  C   C "C5'" 1 
ATOM   6782 C "C4'" . C   C 2 56  ? 120.452 118.805 159.990 1.00 165.90 ? 56  C   C "C4'" 1 
ATOM   6783 O "O4'" . C   C 2 56  ? 119.394 119.774 159.765 1.00 165.90 ? 56  C   C "O4'" 1 
ATOM   6784 C "C3'" . C   C 2 56  ? 120.838 118.344 158.592 1.00 165.90 ? 56  C   C "C3'" 1 
ATOM   6785 O "O3'" . C   C 2 56  ? 121.460 117.071 158.589 1.00 165.90 ? 56  C   C "O3'" 1 
ATOM   6786 C "C2'" . C   C 2 56  ? 119.510 118.375 157.849 1.00 165.90 ? 56  C   C "C2'" 1 
ATOM   6787 O "O2'" . C   C 2 56  ? 118.737 117.225 158.157 1.00 165.90 ? 56  C   C "O2'" 1 
ATOM   6788 C "C1'" . C   C 2 56  ? 118.836 119.593 158.480 1.00 165.90 ? 56  C   C "C1'" 1 
ATOM   6789 N N1    . C   C 2 56  ? 119.052 120.832 157.697 1.00 165.90 ? 56  C   C N1    1 
ATOM   6790 C C2    . C   C 2 56  ? 118.341 121.045 156.509 1.00 165.90 ? 56  C   C C2    1 
ATOM   6791 O O2    . C   C 2 56  ? 117.544 120.178 156.124 1.00 165.90 ? 56  C   C O2    1 
ATOM   6792 N N3    . C   C 2 56  ? 118.551 122.188 155.812 1.00 165.90 ? 56  C   C N3    1 
ATOM   6793 C C4    . C   C 2 56  ? 119.419 123.098 156.259 1.00 165.90 ? 56  C   C C4    1 
ATOM   6794 N N4    . C   C 2 56  ? 119.601 124.214 155.549 1.00 165.90 ? 56  C   C N4    1 
ATOM   6795 C C5    . C   C 2 56  ? 120.149 122.907 157.465 1.00 165.90 ? 56  C   C C5    1 
ATOM   6796 C C6    . C   C 2 56  ? 119.933 121.775 158.143 1.00 165.90 ? 56  C   C C6    1 
ATOM   6797 P P     . U   C 2 57  ? 122.544 116.700 157.462 1.00 161.46 ? 57  U   C P     1 
ATOM   6798 O OP1   . U   C 2 57  ? 123.142 115.387 157.815 1.00 161.46 ? 57  U   C OP1   1 
ATOM   6799 O OP2   . U   C 2 57  ? 123.425 117.879 157.264 1.00 161.46 ? 57  U   C OP2   1 
ATOM   6800 O "O5'" . U   C 2 57  ? 121.677 116.504 156.141 1.00 161.46 ? 57  U   C "O5'" 1 
ATOM   6801 C "C5'" . U   C 2 57  ? 120.740 115.443 156.031 1.00 161.46 ? 57  U   C "C5'" 1 
ATOM   6802 C "C4'" . U   C 2 57  ? 119.990 115.511 154.725 1.00 161.46 ? 57  U   C "C4'" 1 
ATOM   6803 O "O4'" . U   C 2 57  ? 119.164 116.701 154.700 1.00 161.46 ? 57  U   C "O4'" 1 
ATOM   6804 C "C3'" . U   C 2 57  ? 120.852 115.626 153.477 1.00 161.46 ? 57  U   C "C3'" 1 
ATOM   6805 O "O3'" . U   C 2 57  ? 121.334 114.369 153.033 1.00 161.46 ? 57  U   C "O3'" 1 
ATOM   6806 C "C2'" . U   C 2 57  ? 119.922 116.308 152.481 1.00 161.46 ? 57  U   C "C2'" 1 
ATOM   6807 O "O2'" . U   C 2 57  ? 119.031 115.367 151.901 1.00 161.46 ? 57  U   C "O2'" 1 
ATOM   6808 C "C1'" . U   C 2 57  ? 119.118 117.234 153.394 1.00 161.46 ? 57  U   C "C1'" 1 
ATOM   6809 N N1    . U   C 2 57  ? 119.648 118.617 153.433 1.00 161.46 ? 57  U   C N1    1 
ATOM   6810 C C2    . U   C 2 57  ? 119.340 119.474 152.394 1.00 161.46 ? 57  U   C C2    1 
ATOM   6811 O O2    . U   C 2 57  ? 118.669 119.137 151.434 1.00 161.46 ? 57  U   C O2    1 
ATOM   6812 N N3    . U   C 2 57  ? 119.854 120.743 152.514 1.00 161.46 ? 57  U   C N3    1 
ATOM   6813 C C4    . U   C 2 57  ? 120.623 121.230 153.554 1.00 161.46 ? 57  U   C C4    1 
ATOM   6814 O O4    . U   C 2 57  ? 121.021 122.396 153.537 1.00 161.46 ? 57  U   C O4    1 
ATOM   6815 C C5    . U   C 2 57  ? 120.890 120.284 154.591 1.00 161.46 ? 57  U   C C5    1 
ATOM   6816 C C6    . U   C 2 57  ? 120.402 119.045 154.499 1.00 161.46 ? 57  U   C C6    1 
ATOM   6817 P P     . U   C 2 58  ? 122.729 114.266 152.245 1.00 152.85 ? 58  U   C P     1 
ATOM   6818 O OP1   . U   C 2 58  ? 123.107 112.832 152.166 1.00 152.85 ? 58  U   C OP1   1 
ATOM   6819 O OP2   . U   C 2 58  ? 123.672 115.241 152.850 1.00 152.85 ? 58  U   C OP2   1 
ATOM   6820 O "O5'" . U   C 2 58  ? 122.378 114.766 150.774 1.00 152.85 ? 58  U   C "O5'" 1 
ATOM   6821 C "C5'" . U   C 2 58  ? 121.380 114.117 149.998 1.00 152.85 ? 58  U   C "C5'" 1 
ATOM   6822 C "C4'" . U   C 2 58  ? 121.072 114.896 148.745 1.00 152.85 ? 58  U   C "C4'" 1 
ATOM   6823 O "O4'" . U   C 2 58  ? 120.446 116.157 149.095 1.00 152.85 ? 58  U   C "O4'" 1 
ATOM   6824 C "C3'" . U   C 2 58  ? 122.279 115.298 147.914 1.00 152.85 ? 58  U   C "C3'" 1 
ATOM   6825 O "O3'" . U   C 2 58  ? 122.735 114.257 147.069 1.00 152.85 ? 58  U   C "O3'" 1 
ATOM   6826 C "C2'" . U   C 2 58  ? 121.780 116.526 147.163 1.00 152.85 ? 58  U   C "C2'" 1 
ATOM   6827 O "O2'" . U   C 2 58  ? 120.987 116.144 146.048 1.00 152.85 ? 58  U   C "O2'" 1 
ATOM   6828 C "C1'" . U   C 2 58  ? 120.867 117.171 148.206 1.00 152.85 ? 58  U   C "C1'" 1 
ATOM   6829 N N1    . U   C 2 58  ? 121.551 118.226 148.989 1.00 152.85 ? 58  U   C N1    1 
ATOM   6830 C C2    . U   C 2 58  ? 121.671 119.488 148.435 1.00 152.85 ? 58  U   C C2    1 
ATOM   6831 O O2    . U   C 2 58  ? 121.249 119.767 147.327 1.00 152.85 ? 58  U   C O2    1 
ATOM   6832 N N3    . U   C 2 58  ? 122.310 120.413 149.228 1.00 152.85 ? 58  U   C N3    1 
ATOM   6833 C C4    . U   C 2 58  ? 122.824 120.207 150.493 1.00 152.85 ? 58  U   C C4    1 
ATOM   6834 O O4    . U   C 2 58  ? 123.376 121.129 151.096 1.00 152.85 ? 58  U   C O4    1 
ATOM   6835 C C5    . U   C 2 58  ? 122.656 118.879 150.995 1.00 152.85 ? 58  U   C C5    1 
ATOM   6836 C C6    . U   C 2 58  ? 122.040 117.962 150.246 1.00 152.85 ? 58  U   C C6    1 
ATOM   6837 P P     . U   C 2 59  ? 124.304 113.930 146.984 1.00 136.53 ? 59  U   C P     1 
ATOM   6838 O OP1   . U   C 2 59  ? 124.669 113.782 145.552 1.00 136.53 ? 59  U   C OP1   1 
ATOM   6839 O OP2   . U   C 2 59  ? 124.600 112.830 147.937 1.00 136.53 ? 59  U   C OP2   1 
ATOM   6840 O "O5'" . U   C 2 59  ? 124.988 115.256 147.539 1.00 136.53 ? 59  U   C "O5'" 1 
ATOM   6841 C "C5'" . U   C 2 59  ? 126.123 115.813 146.898 1.00 136.53 ? 59  U   C "C5'" 1 
ATOM   6842 C "C4'" . U   C 2 59  ? 125.736 116.930 145.963 1.00 136.53 ? 59  U   C "C4'" 1 
ATOM   6843 O "O4'" . U   C 2 59  ? 124.876 117.875 146.649 1.00 136.53 ? 59  U   C "O4'" 1 
ATOM   6844 C "C3'" . U   C 2 59  ? 126.886 117.776 145.441 1.00 136.53 ? 59  U   C "C3'" 1 
ATOM   6845 O "O3'" . U   C 2 59  ? 127.529 117.179 144.329 1.00 136.53 ? 59  U   C "O3'" 1 
ATOM   6846 C "C2'" . U   C 2 59  ? 126.215 119.104 145.116 1.00 136.53 ? 59  U   C "C2'" 1 
ATOM   6847 O "O2'" . U   C 2 59  ? 125.559 119.038 143.858 1.00 136.53 ? 59  U   C "O2'" 1 
ATOM   6848 C "C1'" . U   C 2 59  ? 125.150 119.189 146.211 1.00 136.53 ? 59  U   C "C1'" 1 
ATOM   6849 N N1    . U   C 2 59  ? 125.579 119.986 147.385 1.00 136.53 ? 59  U   C N1    1 
ATOM   6850 C C2    . U   C 2 59  ? 125.841 121.342 147.261 1.00 136.53 ? 59  U   C C2    1 
ATOM   6851 O O2    . U   C 2 59  ? 125.770 121.954 146.209 1.00 136.53 ? 59  U   C O2    1 
ATOM   6852 N N3    . U   C 2 59  ? 126.215 121.966 148.427 1.00 136.53 ? 59  U   C N3    1 
ATOM   6853 C C4    . U   C 2 59  ? 126.335 121.390 149.677 1.00 136.53 ? 59  U   C C4    1 
ATOM   6854 O O4    . U   C 2 59  ? 126.680 122.068 150.645 1.00 136.53 ? 59  U   C O4    1 
ATOM   6855 C C5    . U   C 2 59  ? 126.035 119.995 149.722 1.00 136.53 ? 59  U   C C5    1 
ATOM   6856 C C6    . U   C 2 59  ? 125.671 119.363 148.606 1.00 136.53 ? 59  U   C C6    1 
ATOM   6857 P P     . G   C 2 60  ? 129.025 117.605 143.930 1.00 115.96 ? 60  G   C P     1 
ATOM   6858 O OP1   . G   C 2 60  ? 129.535 116.618 142.944 1.00 115.96 ? 60  G   C OP1   1 
ATOM   6859 O OP2   . G   C 2 60  ? 129.784 117.853 145.181 1.00 115.96 ? 60  G   C OP2   1 
ATOM   6860 O "O5'" . G   C 2 60  ? 128.840 118.997 143.181 1.00 115.96 ? 60  G   C "O5'" 1 
ATOM   6861 C "C5'" . G   C 2 60  ? 129.964 119.793 142.847 1.00 115.96 ? 60  G   C "C5'" 1 
ATOM   6862 C "C4'" . G   C 2 60  ? 129.588 121.243 142.687 1.00 115.96 ? 60  G   C "C4'" 1 
ATOM   6863 O "O4'" . G   C 2 60  ? 128.563 121.597 143.649 1.00 115.96 ? 60  G   C "O4'" 1 
ATOM   6864 C "C3'" . G   C 2 60  ? 130.706 122.240 142.945 1.00 115.96 ? 60  G   C "C3'" 1 
ATOM   6865 O "O3'" . G   C 2 60  ? 131.551 122.410 141.822 1.00 115.96 ? 60  G   C "O3'" 1 
ATOM   6866 C "C2'" . G   C 2 60  ? 129.951 123.502 143.341 1.00 115.96 ? 60  G   C "C2'" 1 
ATOM   6867 O "O2'" . G   C 2 60  ? 129.463 124.176 142.190 1.00 115.96 ? 60  G   C "O2'" 1 
ATOM   6868 C "C1'" . G   C 2 60  ? 128.758 122.920 144.101 1.00 115.96 ? 60  G   C "C1'" 1 
ATOM   6869 N N9    . G   C 2 60  ? 128.966 122.885 145.562 1.00 115.96 ? 60  G   C N9    1 
ATOM   6870 C C8    . G   C 2 60  ? 128.894 121.764 146.352 1.00 115.96 ? 60  G   C C8    1 
ATOM   6871 N N7    . G   C 2 60  ? 129.103 122.006 147.616 1.00 115.96 ? 60  G   C N7    1 
ATOM   6872 C C5    . G   C 2 60  ? 129.320 123.374 147.669 1.00 115.96 ? 60  G   C C5    1 
ATOM   6873 C C6    . G   C 2 60  ? 129.599 124.207 148.781 1.00 115.96 ? 60  G   C C6    1 
ATOM   6874 O O6    . G   C 2 60  ? 129.713 123.890 149.970 1.00 115.96 ? 60  G   C O6    1 
ATOM   6875 N N1    . G   C 2 60  ? 129.751 125.534 148.400 1.00 115.96 ? 60  G   C N1    1 
ATOM   6876 C C2    . G   C 2 60  ? 129.649 125.998 147.114 1.00 115.96 ? 60  G   C C2    1 
ATOM   6877 N N2    . G   C 2 60  ? 129.827 127.316 146.950 1.00 115.96 ? 60  G   C N2    1 
ATOM   6878 N N3    . G   C 2 60  ? 129.387 125.232 146.067 1.00 115.96 ? 60  G   C N3    1 
ATOM   6879 C C4    . G   C 2 60  ? 129.234 123.936 146.412 1.00 115.96 ? 60  G   C C4    1 
ATOM   6880 P P     . C   C 2 61  ? 133.143 122.266 141.978 1.00 108.92 ? 61  C   C P     1 
ATOM   6881 O OP1   . C   C 2 61  ? 133.729 122.115 140.623 1.00 108.92 ? 61  C   C OP1   1 
ATOM   6882 O OP2   . C   C 2 61  ? 133.416 121.240 143.016 1.00 108.92 ? 61  C   C OP2   1 
ATOM   6883 O "O5'" . C   C 2 61  ? 133.595 123.680 142.550 1.00 108.92 ? 61  C   C "O5'" 1 
ATOM   6884 C "C5'" . C   C 2 61  ? 133.181 124.883 141.921 1.00 108.92 ? 61  C   C "C5'" 1 
ATOM   6885 C "C4'" . C   C 2 61  ? 133.354 126.063 142.839 1.00 108.92 ? 61  C   C "C4'" 1 
ATOM   6886 O "O4'" . C   C 2 61  ? 132.341 126.030 143.878 1.00 108.92 ? 61  C   C "O4'" 1 
ATOM   6887 C "C3'" . C   C 2 61  ? 134.666 126.111 143.605 1.00 108.92 ? 61  C   C "C3'" 1 
ATOM   6888 O "O3'" . C   C 2 61  ? 135.734 126.631 142.835 1.00 108.92 ? 61  C   C "O3'" 1 
ATOM   6889 C "C2'" . C   C 2 61  ? 134.312 126.960 144.817 1.00 108.92 ? 61  C   C "C2'" 1 
ATOM   6890 O "O2'" . C   C 2 61  ? 134.284 128.337 144.475 1.00 108.92 ? 61  C   C "O2'" 1 
ATOM   6891 C "C1'" . C   C 2 61  ? 132.880 126.503 145.094 1.00 108.92 ? 61  C   C "C1'" 1 
ATOM   6892 N N1    . C   C 2 61  ? 132.826 125.404 146.085 1.00 108.92 ? 61  C   C N1    1 
ATOM   6893 C C2    . C   C 2 61  ? 133.000 125.691 147.441 1.00 108.92 ? 61  C   C C2    1 
ATOM   6894 O O2    . C   C 2 61  ? 133.204 126.859 147.797 1.00 108.92 ? 61  C   C O2    1 
ATOM   6895 N N3    . C   C 2 61  ? 132.949 124.685 148.342 1.00 108.92 ? 61  C   C N3    1 
ATOM   6896 C C4    . C   C 2 61  ? 132.729 123.435 147.933 1.00 108.92 ? 61  C   C C4    1 
ATOM   6897 N N4    . C   C 2 61  ? 132.683 122.469 148.852 1.00 108.92 ? 61  C   C N4    1 
ATOM   6898 C C5    . C   C 2 61  ? 132.544 123.113 146.559 1.00 108.92 ? 61  C   C C5    1 
ATOM   6899 C C6    . C   C 2 61  ? 132.599 124.120 145.681 1.00 108.92 ? 61  C   C C6    1 
ATOM   6900 P P     . U   C 2 62  ? 136.805 125.643 142.132 1.00 98.12  ? 62  U   C P     1 
ATOM   6901 O OP1   . U   C 2 62  ? 136.454 125.526 140.696 1.00 98.12  ? 62  U   C OP1   1 
ATOM   6902 O OP2   . U   C 2 62  ? 136.965 124.412 142.955 1.00 98.12  ? 62  U   C OP2   1 
ATOM   6903 O "O5'" . U   C 2 62  ? 138.165 126.456 142.263 1.00 98.12  ? 62  U   C "O5'" 1 
ATOM   6904 C "C5'" . U   C 2 62  ? 139.090 126.126 143.305 1.00 98.12  ? 62  U   C "C5'" 1 
ATOM   6905 C "C4'" . U   C 2 62  ? 139.074 127.187 144.375 1.00 98.12  ? 62  U   C "C4'" 1 
ATOM   6906 O "O4'" . U   C 2 62  ? 137.756 127.246 144.989 1.00 98.12  ? 62  U   C "O4'" 1 
ATOM   6907 C "C3'" . U   C 2 62  ? 140.012 126.924 145.536 1.00 98.12  ? 62  U   C "C3'" 1 
ATOM   6908 O "O3'" . U   C 2 62  ? 141.348 127.309 145.248 1.00 98.12  ? 62  U   C "O3'" 1 
ATOM   6909 C "C2'" . U   C 2 62  ? 139.365 127.730 146.650 1.00 98.12  ? 62  U   C "C2'" 1 
ATOM   6910 O "O2'" . U   C 2 62  ? 139.626 129.114 146.565 1.00 98.12  ? 62  U   C "O2'" 1 
ATOM   6911 C "C1'" . U   C 2 62  ? 137.884 127.461 146.387 1.00 98.12  ? 62  U   C "C1'" 1 
ATOM   6912 N N1    . U   C 2 62  ? 137.354 126.279 147.085 1.00 98.12  ? 62  U   C N1    1 
ATOM   6913 C C2    . U   C 2 62  ? 137.379 126.264 148.466 1.00 98.12  ? 62  U   C C2    1 
ATOM   6914 O O2    . U   C 2 62  ? 137.818 127.184 149.134 1.00 98.12  ? 62  U   C O2    1 
ATOM   6915 N N3    . U   C 2 62  ? 136.860 125.130 149.038 1.00 98.12  ? 62  U   C N3    1 
ATOM   6916 C C4    . U   C 2 62  ? 136.326 124.038 148.392 1.00 98.12  ? 62  U   C C4    1 
ATOM   6917 O O4    . U   C 2 62  ? 135.900 123.090 149.053 1.00 98.12  ? 62  U   C O4    1 
ATOM   6918 C C5    . U   C 2 62  ? 136.329 124.133 146.967 1.00 98.12  ? 62  U   C C5    1 
ATOM   6919 C C6    . U   C 2 62  ? 136.832 125.222 146.376 1.00 98.12  ? 62  U   C C6    1 
ATOM   6920 P P     . C   C 2 63  ? 142.522 126.249 145.446 1.00 99.02  ? 63  C   C P     1 
ATOM   6921 O OP1   . C   C 2 63  ? 143.796 126.986 145.583 1.00 99.02  ? 63  C   C OP1   1 
ATOM   6922 O OP2   . C   C 2 63  ? 142.373 125.193 144.414 1.00 99.02  ? 63  C   C OP2   1 
ATOM   6923 O "O5'" . C   C 2 63  ? 142.220 125.646 146.886 1.00 99.02  ? 63  C   C "O5'" 1 
ATOM   6924 C "C5'" . C   C 2 63  ? 142.387 126.465 148.054 1.00 99.02  ? 63  C   C "C5'" 1 
ATOM   6925 C "C4'" . C   C 2 63  ? 141.990 125.693 149.281 1.00 99.02  ? 63  C   C "C4'" 1 
ATOM   6926 O "O4'" . C   C 2 63  ? 140.587 125.334 149.201 1.00 99.02  ? 63  C   C "O4'" 1 
ATOM   6927 C "C3'" . C   C 2 63  ? 142.696 124.364 149.462 1.00 99.02  ? 63  C   C "C3'" 1 
ATOM   6928 O "O3'" . C   C 2 63  ? 144.008 124.540 149.985 1.00 99.02  ? 63  C   C "O3'" 1 
ATOM   6929 C "C2'" . C   C 2 63  ? 141.734 123.634 150.390 1.00 99.02  ? 63  C   C "C2'" 1 
ATOM   6930 O "O2'" . C   C 2 63  ? 141.873 124.023 151.740 1.00 99.02  ? 63  C   C "O2'" 1 
ATOM   6931 C "C1'" . C   C 2 63  ? 140.380 124.087 149.841 1.00 99.02  ? 63  C   C "C1'" 1 
ATOM   6932 N N1    . C   C 2 63  ? 139.803 123.156 148.860 1.00 99.02  ? 63  C   C N1    1 
ATOM   6933 C C2    . C   C 2 63  ? 139.189 121.988 149.317 1.00 99.02  ? 63  C   C C2    1 
ATOM   6934 O O2    . C   C 2 63  ? 139.150 121.769 150.534 1.00 99.02  ? 63  C   C O2    1 
ATOM   6935 N N3    . C   C 2 63  ? 138.658 121.126 148.421 1.00 99.02  ? 63  C   C N3    1 
ATOM   6936 C C4    . C   C 2 63  ? 138.725 121.396 147.116 1.00 99.02  ? 63  C   C C4    1 
ATOM   6937 N N4    . C   C 2 63  ? 138.186 120.518 146.267 1.00 99.02  ? 63  C   C N4    1 
ATOM   6938 C C5    . C   C 2 63  ? 139.349 122.578 146.622 1.00 99.02  ? 63  C   C C5    1 
ATOM   6939 C C6    . C   C 2 63  ? 139.863 123.425 147.522 1.00 99.02  ? 63  C   C C6    1 
ATOM   6940 P P     . U   C 2 64  ? 145.263 124.576 148.988 1.00 89.96  ? 64  U   C P     1 
ATOM   6941 O OP1   . U   C 2 64  ? 145.798 125.959 148.969 1.00 89.96  ? 64  U   C OP1   1 
ATOM   6942 O OP2   . U   C 2 64  ? 144.864 123.925 147.716 1.00 89.96  ? 64  U   C OP2   1 
ATOM   6943 O "O5'" . U   C 2 64  ? 146.327 123.638 149.708 1.00 89.96  ? 64  U   C "O5'" 1 
ATOM   6944 C "C5'" . U   C 2 64  ? 146.956 124.055 150.929 1.00 89.96  ? 64  U   C "C5'" 1 
ATOM   6945 C "C4'" . U   C 2 64  ? 146.719 123.026 152.003 1.00 89.96  ? 64  U   C "C4'" 1 
ATOM   6946 O "O4'" . U   C 2 64  ? 145.294 122.842 152.174 1.00 89.96  ? 64  U   C "O4'" 1 
ATOM   6947 C "C3'" . U   C 2 64  ? 147.216 121.626 151.688 1.00 89.96  ? 64  U   C "C3'" 1 
ATOM   6948 O "O3'" . U   C 2 64  ? 148.594 121.459 151.987 1.00 89.96  ? 64  U   C "O3'" 1 
ATOM   6949 C "C2'" . U   C 2 64  ? 146.364 120.759 152.607 1.00 89.96  ? 64  U   C "C2'" 1 
ATOM   6950 O "O2'" . U   C 2 64  ? 146.913 120.627 153.901 1.00 89.96  ? 64  U   C "O2'" 1 
ATOM   6951 C "C1'" . U   C 2 64  ? 145.048 121.538 152.661 1.00 89.96  ? 64  U   C "C1'" 1 
ATOM   6952 N N1    . U   C 2 64  ? 143.978 120.930 151.859 1.00 89.96  ? 64  U   C N1    1 
ATOM   6953 C C2    . U   C 2 64  ? 142.989 120.248 152.536 1.00 89.96  ? 64  U   C C2    1 
ATOM   6954 O O2    . U   C 2 64  ? 142.971 120.142 153.749 1.00 89.96  ? 64  U   C O2    1 
ATOM   6955 N N3    . U   C 2 64  ? 142.021 119.696 151.737 1.00 89.96  ? 64  U   C N3    1 
ATOM   6956 C C4    . U   C 2 64  ? 141.937 119.755 150.364 1.00 89.96  ? 64  U   C C4    1 
ATOM   6957 O O4    . U   C 2 64  ? 140.999 119.202 149.790 1.00 89.96  ? 64  U   C O4    1 
ATOM   6958 C C5    . U   C 2 64  ? 143.004 120.469 149.736 1.00 89.96  ? 64  U   C C5    1 
ATOM   6959 C C6    . U   C 2 64  ? 143.967 121.017 150.487 1.00 89.96  ? 64  U   C C6    1 
ATOM   6960 P P     . C   C 2 65  ? 149.396 120.237 151.347 1.00 86.88  ? 65  C   C P     1 
ATOM   6961 O OP1   . C   C 2 65  ? 150.782 120.692 151.073 1.00 86.88  ? 65  C   C OP1   1 
ATOM   6962 O OP2   . C   C 2 65  ? 148.577 119.673 150.245 1.00 86.88  ? 65  C   C OP2   1 
ATOM   6963 O "O5'" . C   C 2 65  ? 149.435 119.172 152.530 1.00 86.88  ? 65  C   C "O5'" 1 
ATOM   6964 C "C5'" . C   C 2 65  ? 149.381 117.762 152.251 1.00 86.88  ? 65  C   C "C5'" 1 
ATOM   6965 C "C4'" . C   C 2 65  ? 148.619 117.045 153.339 1.00 86.88  ? 65  C   C "C4'" 1 
ATOM   6966 O "O4'" . C   C 2 65  ? 147.322 117.679 153.491 1.00 86.88  ? 65  C   C "O4'" 1 
ATOM   6967 C "C3'" . C   C 2 65  ? 148.318 115.578 153.069 1.00 86.88  ? 65  C   C "C3'" 1 
ATOM   6968 O "O3'" . C   C 2 65  ? 149.331 114.704 153.552 1.00 86.88  ? 65  C   C "O3'" 1 
ATOM   6969 C "C2'" . C   C 2 65  ? 147.040 115.357 153.865 1.00 86.88  ? 65  C   C "C2'" 1 
ATOM   6970 O "O2'" . C   C 2 65  ? 147.276 115.108 155.235 1.00 86.88  ? 65  C   C "O2'" 1 
ATOM   6971 C "C1'" . C   C 2 65  ? 146.324 116.695 153.685 1.00 86.88  ? 65  C   C "C1'" 1 
ATOM   6972 N N1    . C   C 2 65  ? 145.413 116.731 152.531 1.00 86.88  ? 65  C   C N1    1 
ATOM   6973 C C2    . C   C 2 65  ? 144.232 115.987 152.576 1.00 86.88  ? 65  C   C C2    1 
ATOM   6974 O O2    . C   C 2 65  ? 143.986 115.312 153.585 1.00 86.88  ? 65  C   C O2    1 
ATOM   6975 N N3    . C   C 2 65  ? 143.389 116.022 151.520 1.00 86.88  ? 65  C   C N3    1 
ATOM   6976 C C4    . C   C 2 65  ? 143.683 116.773 150.458 1.00 86.88  ? 65  C   C C4    1 
ATOM   6977 N N4    . C   C 2 65  ? 142.824 116.773 149.436 1.00 86.88  ? 65  C   C N4    1 
ATOM   6978 C C5    . C   C 2 65  ? 144.878 117.544 150.387 1.00 86.88  ? 65  C   C C5    1 
ATOM   6979 C C6    . C   C 2 65  ? 145.704 117.498 151.438 1.00 86.88  ? 65  C   C C6    1 
ATOM   6980 P P     . U   C 2 66  ? 150.221 113.855 152.527 1.00 79.86  ? 66  U   C P     1 
ATOM   6981 O OP1   . U   C 2 66  ? 151.285 113.172 153.300 1.00 79.86  ? 66  U   C OP1   1 
ATOM   6982 O OP2   . U   C 2 66  ? 150.587 114.740 151.395 1.00 79.86  ? 66  U   C OP2   1 
ATOM   6983 O "O5'" . U   C 2 66  ? 149.217 112.745 151.985 1.00 79.86  ? 66  U   C "O5'" 1 
ATOM   6984 C "C5'" . U   C 2 66  ? 148.701 111.716 152.845 1.00 79.86  ? 66  U   C "C5'" 1 
ATOM   6985 C "C4'" . U   C 2 66  ? 147.301 111.355 152.419 1.00 79.86  ? 66  U   C "C4'" 1 
ATOM   6986 O "O4'" . U   C 2 66  ? 146.549 112.584 152.239 1.00 79.86  ? 66  U   C "O4'" 1 
ATOM   6987 C "C3'" . U   C 2 66  ? 147.187 110.642 151.081 1.00 79.86  ? 66  U   C "C3'" 1 
ATOM   6988 O "O3'" . U   C 2 66  ? 147.332 109.219 151.169 1.00 79.86  ? 66  U   C "O3'" 1 
ATOM   6989 C "C2'" . U   C 2 66  ? 145.778 111.013 150.635 1.00 79.86  ? 66  U   C "C2'" 1 
ATOM   6990 O "O2'" . U   C 2 66  ? 144.792 110.183 151.209 1.00 79.86  ? 66  U   C "O2'" 1 
ATOM   6991 C "C1'" . U   C 2 66  ? 145.649 112.445 151.155 1.00 79.86  ? 66  U   C "C1'" 1 
ATOM   6992 N N1    . U   C 2 66  ? 145.971 113.464 150.145 1.00 79.86  ? 66  U   C N1    1 
ATOM   6993 C C2    . U   C 2 66  ? 144.995 113.777 149.223 1.00 79.86  ? 66  U   C C2    1 
ATOM   6994 O O2    . U   C 2 66  ? 143.895 113.259 149.224 1.00 79.86  ? 66  U   C O2    1 
ATOM   6995 N N3    . U   C 2 66  ? 145.355 114.727 148.302 1.00 79.86  ? 66  U   C N3    1 
ATOM   6996 C C4    . U   C 2 66  ? 146.564 115.378 148.203 1.00 79.86  ? 66  U   C C4    1 
ATOM   6997 O O4    . U   C 2 66  ? 146.733 116.213 147.314 1.00 79.86  ? 66  U   C O4    1 
ATOM   6998 C C5    . U   C 2 66  ? 147.524 114.998 149.193 1.00 79.86  ? 66  U   C C5    1 
ATOM   6999 C C6    . U   C 2 66  ? 147.201 114.077 150.108 1.00 79.86  ? 66  U   C C6    1 
ATOM   7000 P P     . U   C 2 67  ? 148.748 108.499 150.843 1.00 76.56  ? 67  U   C P     1 
ATOM   7001 O OP1   . U   C 2 67  ? 149.451 108.282 152.132 1.00 76.56  ? 67  U   C OP1   1 
ATOM   7002 O OP2   . U   C 2 67  ? 149.425 109.251 149.757 1.00 76.56  ? 67  U   C OP2   1 
ATOM   7003 O "O5'" . U   C 2 67  ? 148.319 107.075 150.270 1.00 76.56  ? 67  U   C "O5'" 1 
ATOM   7004 C "C5'" . U   C 2 67  ? 148.281 106.830 148.872 1.00 76.56  ? 67  U   C "C5'" 1 
ATOM   7005 C "C4'" . U   C 2 67  ? 146.944 107.197 148.277 1.00 76.56  ? 67  U   C "C4'" 1 
ATOM   7006 O "O4'" . U   C 2 67  ? 146.669 108.598 148.525 1.00 76.56  ? 67  U   C "O4'" 1 
ATOM   7007 C "C3'" . U   C 2 67  ? 146.831 107.053 146.766 1.00 76.56  ? 67  U   C "C3'" 1 
ATOM   7008 O "O3'" . U   C 2 67  ? 146.524 105.728 146.374 1.00 76.56  ? 67  U   C "O3'" 1 
ATOM   7009 C "C2'" . U   C 2 67  ? 145.734 108.048 146.403 1.00 76.56  ? 67  U   C "C2'" 1 
ATOM   7010 O "O2'" . U   C 2 67  ? 144.454 107.465 146.595 1.00 76.56  ? 67  U   C "O2'" 1 
ATOM   7011 C "C1'" . U   C 2 67  ? 145.928 109.142 147.456 1.00 76.56  ? 67  U   C "C1'" 1 
ATOM   7012 N N1    . U   C 2 67  ? 146.606 110.358 146.942 1.00 76.56  ? 67  U   C N1    1 
ATOM   7013 C C2    . U   C 2 67  ? 147.983 110.412 146.784 1.00 76.56  ? 67  U   C C2    1 
ATOM   7014 O O2    . U   C 2 67  ? 148.745 109.497 147.035 1.00 76.56  ? 67  U   C O2    1 
ATOM   7015 N N3    . U   C 2 67  ? 148.463 111.607 146.305 1.00 76.56  ? 67  U   C N3    1 
ATOM   7016 C C4    . U   C 2 67  ? 147.740 112.734 145.978 1.00 76.56  ? 67  U   C C4    1 
ATOM   7017 O O4    . U   C 2 67  ? 148.327 113.732 145.556 1.00 76.56  ? 67  U   C O4    1 
ATOM   7018 C C5    . U   C 2 67  ? 146.331 112.603 146.167 1.00 76.56  ? 67  U   C C5    1 
ATOM   7019 C C6    . U   C 2 67  ? 145.834 111.454 146.632 1.00 76.56  ? 67  U   C C6    1 
ATOM   7020 P P     . C   C 2 68  ? 147.621 104.811 145.641 1.00 81.53  ? 68  C   C P     1 
ATOM   7021 O OP1   . C   C 2 68  ? 148.500 104.226 146.685 1.00 81.53  ? 68  C   C OP1   1 
ATOM   7022 O OP2   . C   C 2 68  ? 148.222 105.592 144.531 1.00 81.53  ? 68  C   C OP2   1 
ATOM   7023 O "O5'" . C   C 2 68  ? 146.755 103.636 145.002 1.00 81.53  ? 68  C   C "O5'" 1 
ATOM   7024 C "C5'" . C   C 2 68  ? 147.373 102.477 144.468 1.00 81.53  ? 68  C   C "C5'" 1 
ATOM   7025 C "C4'" . C   C 2 68  ? 146.925 102.208 143.053 1.00 81.53  ? 68  C   C "C4'" 1 
ATOM   7026 O "O4'" . C   C 2 68  ? 145.507 101.906 143.022 1.00 81.53  ? 68  C   C "O4'" 1 
ATOM   7027 C "C3'" . C   C 2 68  ? 147.069 103.360 142.074 1.00 81.53  ? 68  C   C "C3'" 1 
ATOM   7028 O "O3'" . C   C 2 68  ? 148.394 103.535 141.606 1.00 81.53  ? 68  C   C "O3'" 1 
ATOM   7029 C "C2'" . C   C 2 68  ? 146.072 102.999 140.977 1.00 81.53  ? 68  C   C "C2'" 1 
ATOM   7030 O "O2'" . C   C 2 68  ? 146.637 102.059 140.075 1.00 81.53  ? 68  C   C "O2'" 1 
ATOM   7031 C "C1'" . C   C 2 68  ? 144.968 102.296 141.776 1.00 81.53  ? 68  C   C "C1'" 1 
ATOM   7032 N N1    . C   C 2 68  ? 143.751 103.126 141.969 1.00 81.53  ? 68  C   C N1    1 
ATOM   7033 C C2    . C   C 2 68  ? 143.705 104.254 142.805 1.00 81.53  ? 68  C   C C2    1 
ATOM   7034 O O2    . C   C 2 68  ? 144.696 104.604 143.455 1.00 81.53  ? 68  C   C O2    1 
ATOM   7035 N N3    . C   C 2 68  ? 142.553 104.954 142.914 1.00 81.53  ? 68  C   C N3    1 
ATOM   7036 C C4    . C   C 2 68  ? 141.476 104.585 142.227 1.00 81.53  ? 68  C   C C4    1 
ATOM   7037 N N4    . C   C 2 68  ? 140.366 105.309 142.366 1.00 81.53  ? 68  C   C N4    1 
ATOM   7038 C C5    . C   C 2 68  ? 141.490 103.456 141.364 1.00 81.53  ? 68  C   C C5    1 
ATOM   7039 C C6    . C   C 2 68  ? 142.633 102.771 141.267 1.00 81.53  ? 68  C   C C6    1 
ATOM   7040 P P     . G   C 2 69  ? 148.910 105.007 141.226 1.00 71.76  ? 69  G   C P     1 
ATOM   7041 O OP1   . G   C 2 69  ? 149.021 105.100 139.749 1.00 71.76  ? 69  G   C OP1   1 
ATOM   7042 O OP2   . G   C 2 69  ? 150.085 105.321 142.077 1.00 71.76  ? 69  G   C OP2   1 
ATOM   7043 O "O5'" . G   C 2 69  ? 147.715 105.947 141.692 1.00 71.76  ? 69  G   C "O5'" 1 
ATOM   7044 C "C5'" . G   C 2 69  ? 147.534 107.234 141.125 1.00 71.76  ? 69  G   C "C5'" 1 
ATOM   7045 C "C4'" . G   C 2 69  ? 147.647 108.311 142.171 1.00 71.76  ? 69  G   C "C4'" 1 
ATOM   7046 O "O4'" . G   C 2 69  ? 149.030 108.445 142.584 1.00 71.76  ? 69  G   C "O4'" 1 
ATOM   7047 C "C3'" . G   C 2 69  ? 147.251 109.710 141.728 1.00 71.76  ? 69  G   C "C3'" 1 
ATOM   7048 O "O3'" . G   C 2 69  ? 145.851 109.920 141.795 1.00 71.76  ? 69  G   C "O3'" 1 
ATOM   7049 C "C2'" . G   C 2 69  ? 148.032 110.600 142.685 1.00 71.76  ? 69  G   C "C2'" 1 
ATOM   7050 O "O2'" . G   C 2 69  ? 147.362 110.686 143.930 1.00 71.76  ? 69  G   C "O2'" 1 
ATOM   7051 C "C1'" . G   C 2 69  ? 149.316 109.793 142.884 1.00 71.76  ? 69  G   C "C1'" 1 
ATOM   7052 N N9    . G   C 2 69  ? 150.413 110.251 142.010 1.00 71.76  ? 69  G   C N9    1 
ATOM   7053 C C8    . G   C 2 69  ? 150.974 109.563 140.962 1.00 71.76  ? 69  G   C C8    1 
ATOM   7054 N N7    . G   C 2 69  ? 151.937 110.219 140.374 1.00 71.76  ? 69  G   C N7    1 
ATOM   7055 C C5    . G   C 2 69  ? 152.020 111.412 141.078 1.00 71.76  ? 69  G   C C5    1 
ATOM   7056 C C6    . G   C 2 69  ? 152.883 112.524 140.899 1.00 71.76  ? 69  G   C C6    1 
ATOM   7057 O O6    . G   C 2 69  ? 153.773 112.682 140.055 1.00 71.76  ? 69  G   C O6    1 
ATOM   7058 N N1    . G   C 2 69  ? 152.628 113.522 141.834 1.00 71.76  ? 69  G   C N1    1 
ATOM   7059 C C2    . G   C 2 69  ? 151.669 113.461 142.814 1.00 71.76  ? 69  G   C C2    1 
ATOM   7060 N N2    . G   C 2 69  ? 151.579 114.529 143.620 1.00 71.76  ? 69  G   C N2    1 
ATOM   7061 N N3    . G   C 2 69  ? 150.859 112.429 142.991 1.00 71.76  ? 69  G   C N3    1 
ATOM   7062 C C4    . G   C 2 69  ? 151.088 111.447 142.094 1.00 71.76  ? 69  G   C C4    1 
ATOM   7063 P P     . G   C 2 70  ? 145.042 110.485 140.527 1.00 71.45  ? 70  G   C P     1 
ATOM   7064 O OP1   . G   C 2 70  ? 143.714 109.824 140.513 1.00 71.45  ? 70  G   C OP1   1 
ATOM   7065 O OP2   . G   C 2 70  ? 145.921 110.378 139.337 1.00 71.45  ? 70  G   C OP2   1 
ATOM   7066 O "O5'" . G   C 2 70  ? 144.824 112.031 140.854 1.00 71.45  ? 70  G   C "O5'" 1 
ATOM   7067 C "C5'" . G   C 2 70  ? 145.924 112.925 140.927 1.00 71.45  ? 70  G   C "C5'" 1 
ATOM   7068 C "C4'" . G   C 2 70  ? 146.164 113.615 139.608 1.00 71.45  ? 70  G   C "C4'" 1 
ATOM   7069 O "O4'" . G   C 2 70  ? 145.433 114.864 139.566 1.00 71.45  ? 70  G   C "O4'" 1 
ATOM   7070 C "C3'" . G   C 2 70  ? 147.600 114.020 139.313 1.00 71.45  ? 70  G   C "C3'" 1 
ATOM   7071 O "O3'" . G   C 2 70  ? 148.382 112.941 138.829 1.00 71.45  ? 70  G   C "O3'" 1 
ATOM   7072 C "C2'" . G   C 2 70  ? 147.434 115.148 138.300 1.00 71.45  ? 70  G   C "C2'" 1 
ATOM   7073 O "O2'" . G   C 2 70  ? 147.257 114.622 136.994 1.00 71.45  ? 70  G   C "O2'" 1 
ATOM   7074 C "C1'" . G   C 2 70  ? 146.118 115.791 138.751 1.00 71.45  ? 70  G   C "C1'" 1 
ATOM   7075 N N9    . G   C 2 70  ? 146.303 117.064 139.480 1.00 71.45  ? 70  G   C N9    1 
ATOM   7076 C C8    . G   C 2 70  ? 145.731 118.258 139.110 1.00 71.45  ? 70  G   C C8    1 
ATOM   7077 N N7    . G   C 2 70  ? 146.031 119.251 139.895 1.00 71.45  ? 70  G   C N7    1 
ATOM   7078 C C5    . G   C 2 70  ? 146.860 118.684 140.848 1.00 71.45  ? 70  G   C C5    1 
ATOM   7079 C C6    . G   C 2 70  ? 147.499 119.286 141.962 1.00 71.45  ? 70  G   C C6    1 
ATOM   7080 O O6    . G   C 2 70  ? 147.453 120.466 142.328 1.00 71.45  ? 70  G   C O6    1 
ATOM   7081 N N1    . G   C 2 70  ? 148.252 118.364 142.679 1.00 71.45  ? 70  G   C N1    1 
ATOM   7082 C C2    . G   C 2 70  ? 148.374 117.035 142.364 1.00 71.45  ? 70  G   C C2    1 
ATOM   7083 N N2    . G   C 2 70  ? 149.147 116.304 143.180 1.00 71.45  ? 70  G   C N2    1 
ATOM   7084 N N3    . G   C 2 70  ? 147.782 116.463 141.328 1.00 71.45  ? 70  G   C N3    1 
ATOM   7085 C C4    . G   C 2 70  ? 147.044 117.336 140.611 1.00 71.45  ? 70  G   C C4    1 
ATOM   7086 P P     . A   C 2 71  ? 149.886 113.185 138.319 1.00 71.10  ? 71  A   C P     1 
ATOM   7087 O OP1   . A   C 2 71  ? 150.596 111.882 138.357 1.00 71.10  ? 71  A   C OP1   1 
ATOM   7088 O OP2   . A   C 2 71  ? 150.448 114.351 139.044 1.00 71.10  ? 71  A   C OP2   1 
ATOM   7089 O "O5'" . A   C 2 71  ? 149.717 113.585 136.787 1.00 71.10  ? 71  A   C "O5'" 1 
ATOM   7090 C "C5'" . A   C 2 71  ? 149.985 112.649 135.754 1.00 71.10  ? 71  A   C "C5'" 1 
ATOM   7091 C "C4'" . A   C 2 71  ? 148.829 111.705 135.550 1.00 71.10  ? 71  A   C "C4'" 1 
ATOM   7092 O "O4'" . A   C 2 71  ? 147.578 112.436 135.584 1.00 71.10  ? 71  A   C "O4'" 1 
ATOM   7093 C "C3'" . A   C 2 71  ? 148.783 110.980 134.216 1.00 71.10  ? 71  A   C "C3'" 1 
ATOM   7094 O "O3'" . A   C 2 71  ? 149.675 109.883 134.141 1.00 71.10  ? 71  A   C "O3'" 1 
ATOM   7095 C "C2'" . A   C 2 71  ? 147.316 110.592 134.109 1.00 71.10  ? 71  A   C "C2'" 1 
ATOM   7096 O "O2'" . A   C 2 71  ? 147.035 109.466 134.926 1.00 71.10  ? 71  A   C "O2'" 1 
ATOM   7097 C "C1'" . A   C 2 71  ? 146.639 111.816 134.728 1.00 71.10  ? 71  A   C "C1'" 1 
ATOM   7098 N N9    . A   C 2 71  ? 146.211 112.781 133.699 1.00 71.10  ? 71  A   C N9    1 
ATOM   7099 C C8    . A   C 2 71  ? 146.021 112.525 132.366 1.00 71.10  ? 71  A   C C8    1 
ATOM   7100 N N7    . A   C 2 71  ? 145.621 113.562 131.676 1.00 71.10  ? 71  A   C N7    1 
ATOM   7101 C C5    . A   C 2 71  ? 145.534 114.571 132.621 1.00 71.10  ? 71  A   C C5    1 
ATOM   7102 C C6    . A   C 2 71  ? 145.163 115.920 132.523 1.00 71.10  ? 71  A   C C6    1 
ATOM   7103 N N6    . A   C 2 71  ? 144.797 116.503 131.380 1.00 71.10  ? 71  A   C N6    1 
ATOM   7104 N N1    . A   C 2 71  ? 145.180 116.660 133.650 1.00 71.10  ? 71  A   C N1    1 
ATOM   7105 C C2    . A   C 2 71  ? 145.547 116.069 134.792 1.00 71.10  ? 71  A   C C2    1 
ATOM   7106 N N3    . A   C 2 71  ? 145.917 114.811 135.012 1.00 71.10  ? 71  A   C N3    1 
ATOM   7107 C C4    . A   C 2 71  ? 145.886 114.103 133.873 1.00 71.10  ? 71  A   C C4    1 
ATOM   7108 P P     . A   C 2 72  ? 150.729 109.797 132.931 1.00 73.03  ? 72  A   C P     1 
ATOM   7109 O OP1   . A   C 2 72  ? 151.270 108.416 132.878 1.00 73.03  ? 72  A   C OP1   1 
ATOM   7110 O OP2   . A   C 2 72  ? 151.660 110.947 133.046 1.00 73.03  ? 72  A   C OP2   1 
ATOM   7111 O "O5'" . A   C 2 72  ? 149.833 110.022 131.635 1.00 73.03  ? 72  A   C "O5'" 1 
ATOM   7112 C "C5'" . A   C 2 72  ? 150.367 110.662 130.487 1.00 73.03  ? 72  A   C "C5'" 1 
ATOM   7113 C "C4'" . A   C 2 72  ? 149.374 110.687 129.353 1.00 73.03  ? 72  A   C "C4'" 1 
ATOM   7114 O "O4'" . A   C 2 72  ? 148.157 111.349 129.775 1.00 73.03  ? 72  A   C "O4'" 1 
ATOM   7115 C "C3'" . A   C 2 72  ? 149.802 111.454 128.112 1.00 73.03  ? 72  A   C "C3'" 1 
ATOM   7116 O "O3'" . A   C 2 72  ? 150.643 110.688 127.267 1.00 73.03  ? 72  A   C "O3'" 1 
ATOM   7117 C "C2'" . A   C 2 72  ? 148.473 111.814 127.459 1.00 73.03  ? 72  A   C "C2'" 1 
ATOM   7118 O "O2'" . A   C 2 72  ? 147.987 110.728 126.687 1.00 73.03  ? 72  A   C "O2'" 1 
ATOM   7119 C "C1'" . A   C 2 72  ? 147.556 111.991 128.673 1.00 73.03  ? 72  A   C "C1'" 1 
ATOM   7120 N N9    . A   C 2 72  ? 147.290 113.407 128.995 1.00 73.03  ? 72  A   C N9    1 
ATOM   7121 C C8    . A   C 2 72  ? 146.249 114.161 128.521 1.00 73.03  ? 72  A   C C8    1 
ATOM   7122 N N7    . A   C 2 72  ? 146.236 115.397 128.953 1.00 73.03  ? 72  A   C N7    1 
ATOM   7123 C C5    . A   C 2 72  ? 147.351 115.466 129.768 1.00 73.03  ? 72  A   C C5    1 
ATOM   7124 C C6    . A   C 2 72  ? 147.892 116.516 130.526 1.00 73.03  ? 72  A   C C6    1 
ATOM   7125 N N6    . A   C 2 72  ? 147.367 117.740 130.589 1.00 73.03  ? 72  A   C N6    1 
ATOM   7126 N N1    . A   C 2 72  ? 149.012 116.259 131.228 1.00 73.03  ? 72  A   C N1    1 
ATOM   7127 C C2    . A   C 2 72  ? 149.526 115.028 131.162 1.00 73.03  ? 72  A   C C2    1 
ATOM   7128 N N3    . A   C 2 72  ? 149.122 113.960 130.487 1.00 73.03  ? 72  A   C N3    1 
ATOM   7129 C C4    . A   C 2 72  ? 148.013 114.250 129.799 1.00 73.03  ? 72  A   C C4    1 
ATOM   7130 P P     . G   C 2 73  ? 152.192 111.072 127.089 1.00 89.79  ? 73  G   C P     1 
ATOM   7131 O OP1   . G   C 2 73  ? 152.741 110.259 125.975 1.00 89.79  ? 73  G   C OP1   1 
ATOM   7132 O OP2   . G   C 2 73  ? 152.844 111.024 128.421 1.00 89.79  ? 73  G   C OP2   1 
ATOM   7133 O "O5'" . G   C 2 73  ? 152.160 112.590 126.617 1.00 89.79  ? 73  G   C "O5'" 1 
ATOM   7134 C "C5'" . G   C 2 73  ? 153.336 113.382 126.651 1.00 89.79  ? 73  G   C "C5'" 1 
ATOM   7135 C "C4'" . G   C 2 73  ? 153.006 114.837 126.855 1.00 89.79  ? 73  G   C "C4'" 1 
ATOM   7136 O "O4'" . G   C 2 73  ? 151.997 114.966 127.886 1.00 89.79  ? 73  G   C "O4'" 1 
ATOM   7137 C "C3'" . G   C 2 73  ? 154.146 115.716 127.340 1.00 89.79  ? 73  G   C "C3'" 1 
ATOM   7138 O "O3'" . G   C 2 73  ? 155.004 116.128 126.291 1.00 89.79  ? 73  G   C "O3'" 1 
ATOM   7139 C "C2'" . G   C 2 73  ? 153.417 116.867 128.020 1.00 89.79  ? 73  G   C "C2'" 1 
ATOM   7140 O "O2'" . G   C 2 73  ? 152.947 117.799 127.059 1.00 89.79  ? 73  G   C "O2'" 1 
ATOM   7141 C "C1'" . G   C 2 73  ? 152.206 116.153 128.619 1.00 89.79  ? 73  G   C "C1'" 1 
ATOM   7142 N N9    . G   C 2 73  ? 152.374 115.810 130.046 1.00 89.79  ? 73  G   C N9    1 
ATOM   7143 C C8    . G   C 2 73  ? 152.602 114.563 130.578 1.00 89.79  ? 73  G   C C8    1 
ATOM   7144 N N7    . G   C 2 73  ? 152.676 114.568 131.882 1.00 89.79  ? 73  G   C N7    1 
ATOM   7145 C C5    . G   C 2 73  ? 152.484 115.897 132.233 1.00 89.79  ? 73  G   C C5    1 
ATOM   7146 C C6    . G   C 2 73  ? 152.461 116.517 133.508 1.00 89.79  ? 73  G   C C6    1 
ATOM   7147 O O6    . G   C 2 73  ? 152.612 115.994 134.618 1.00 89.79  ? 73  G   C O6    1 
ATOM   7148 N N1    . G   C 2 73  ? 152.233 117.886 133.412 1.00 89.79  ? 73  G   C N1    1 
ATOM   7149 C C2    . G   C 2 73  ? 152.050 118.571 132.237 1.00 89.79  ? 73  G   C C2    1 
ATOM   7150 N N2    . G   C 2 73  ? 151.839 119.892 132.321 1.00 89.79  ? 73  G   C N2    1 
ATOM   7151 N N3    . G   C 2 73  ? 152.067 118.002 131.044 1.00 89.79  ? 73  G   C N3    1 
ATOM   7152 C C4    . G   C 2 73  ? 152.291 116.675 131.113 1.00 89.79  ? 73  G   C C4    1 
ATOM   7153 P P     . A   C 2 74  ? 156.483 116.665 126.617 1.00 116.59 ? 74  A   C P     1 
ATOM   7154 O OP1   . A   C 2 74  ? 157.255 116.671 125.349 1.00 116.59 ? 74  A   C OP1   1 
ATOM   7155 O OP2   . A   C 2 74  ? 157.000 115.910 127.786 1.00 116.59 ? 74  A   C OP2   1 
ATOM   7156 O "O5'" . A   C 2 74  ? 156.253 118.177 127.063 1.00 116.59 ? 74  A   C "O5'" 1 
ATOM   7157 C "C5'" . A   C 2 74  ? 155.657 119.111 126.177 1.00 116.59 ? 74  A   C "C5'" 1 
ATOM   7158 C "C4'" . A   C 2 74  ? 155.399 120.433 126.854 1.00 116.59 ? 74  A   C "C4'" 1 
ATOM   7159 O "O4'" . A   C 2 74  ? 154.396 120.275 127.888 1.00 116.59 ? 74  A   C "O4'" 1 
ATOM   7160 C "C3'" . A   C 2 74  ? 156.588 121.042 127.575 1.00 116.59 ? 74  A   C "C3'" 1 
ATOM   7161 O "O3'" . A   C 2 74  ? 157.447 121.740 126.691 1.00 116.59 ? 74  A   C "O3'" 1 
ATOM   7162 C "C2'" . A   C 2 74  ? 155.931 121.935 128.620 1.00 116.59 ? 74  A   C "C2'" 1 
ATOM   7163 O "O2'" . A   C 2 74  ? 155.518 123.164 128.041 1.00 116.59 ? 74  A   C "O2'" 1 
ATOM   7164 C "C1'" . A   C 2 74  ? 154.684 121.127 128.976 1.00 116.59 ? 74  A   C "C1'" 1 
ATOM   7165 N N9    . A   C 2 74  ? 154.856 120.294 130.181 1.00 116.59 ? 74  A   C N9    1 
ATOM   7166 C C8    . A   C 2 74  ? 154.837 118.924 130.206 1.00 116.59 ? 74  A   C C8    1 
ATOM   7167 N N7    . A   C 2 74  ? 154.991 118.402 131.393 1.00 116.59 ? 74  A   C N7    1 
ATOM   7168 C C5    . A   C 2 74  ? 155.113 119.509 132.215 1.00 116.59 ? 74  A   C C5    1 
ATOM   7169 C C6    . A   C 2 74  ? 155.301 119.613 133.598 1.00 116.59 ? 74  A   C C6    1 
ATOM   7170 N N6    . A   C 2 74  ? 155.396 118.550 134.397 1.00 116.59 ? 74  A   C N6    1 
ATOM   7171 N N1    . A   C 2 74  ? 155.388 120.847 134.131 1.00 116.59 ? 74  A   C N1    1 
ATOM   7172 C C2    . A   C 2 74  ? 155.288 121.907 133.314 1.00 116.59 ? 74  A   C C2    1 
ATOM   7173 N N3    . A   C 2 74  ? 155.110 121.934 131.991 1.00 116.59 ? 74  A   C N3    1 
ATOM   7174 C C4    . A   C 2 74  ? 155.027 120.686 131.492 1.00 116.59 ? 74  A   C C4    1 
ATOM   7175 P P     . A   C 2 75  ? 159.037 121.690 126.898 1.00 152.62 ? 75  A   C P     1 
ATOM   7176 O OP1   . A   C 2 75  ? 159.679 122.141 125.637 1.00 152.62 ? 75  A   C OP1   1 
ATOM   7177 O OP2   . A   C 2 75  ? 159.387 120.364 127.467 1.00 152.62 ? 75  A   C OP2   1 
ATOM   7178 O "O5'" . A   C 2 75  ? 159.304 122.794 128.011 1.00 152.62 ? 75  A   C "O5'" 1 
ATOM   7179 C "C5'" . A   C 2 75  ? 158.758 124.098 127.889 1.00 152.62 ? 75  A   C "C5'" 1 
ATOM   7180 C "C4'" . A   C 2 75  ? 158.889 124.862 129.180 1.00 152.62 ? 75  A   C "C4'" 1 
ATOM   7181 O "O4'" . A   C 2 75  ? 157.881 124.414 130.122 1.00 152.62 ? 75  A   C "O4'" 1 
ATOM   7182 C "C3'" . A   C 2 75  ? 160.202 124.665 129.918 1.00 152.62 ? 75  A   C "C3'" 1 
ATOM   7183 O "O3'" . A   C 2 75  ? 161.244 125.477 129.406 1.00 152.62 ? 75  A   C "O3'" 1 
ATOM   7184 C "C2'" . A   C 2 75  ? 159.827 124.977 131.360 1.00 152.62 ? 75  A   C "C2'" 1 
ATOM   7185 O "O2'" . A   C 2 75  ? 159.756 126.380 131.567 1.00 152.62 ? 75  A   C "O2'" 1 
ATOM   7186 C "C1'" . A   C 2 75  ? 158.411 124.409 131.431 1.00 152.62 ? 75  A   C "C1'" 1 
ATOM   7187 N N9    . A   C 2 75  ? 158.383 123.022 131.933 1.00 152.62 ? 75  A   C N9    1 
ATOM   7188 C C8    . A   C 2 75  ? 158.133 121.892 131.196 1.00 152.62 ? 75  A   C C8    1 
ATOM   7189 N N7    . A   C 2 75  ? 158.153 120.785 131.892 1.00 152.62 ? 75  A   C N7    1 
ATOM   7190 C C5    . A   C 2 75  ? 158.437 121.213 133.178 1.00 152.62 ? 75  A   C C5    1 
ATOM   7191 C C6    . A   C 2 75  ? 158.592 120.512 134.382 1.00 152.62 ? 75  A   C C6    1 
ATOM   7192 N N6    . A   C 2 75  ? 158.481 119.187 134.473 1.00 152.62 ? 75  A   C N6    1 
ATOM   7193 N N1    . A   C 2 75  ? 158.871 121.224 135.493 1.00 152.62 ? 75  A   C N1    1 
ATOM   7194 C C2    . A   C 2 75  ? 158.981 122.556 135.390 1.00 152.62 ? 75  A   C C2    1 
ATOM   7195 N N3    . A   C 2 75  ? 158.855 123.330 134.312 1.00 152.62 ? 75  A   C N3    1 
ATOM   7196 C C4    . A   C 2 75  ? 158.579 122.589 133.224 1.00 152.62 ? 75  A   C C4    1 
ATOM   7197 P P     . C   C 2 76  ? 162.727 124.881 129.253 1.00 177.22 ? 76  C   C P     1 
ATOM   7198 O OP1   . C   C 2 76  ? 163.523 125.833 128.438 1.00 177.22 ? 76  C   C OP1   1 
ATOM   7199 O OP2   . C   C 2 76  ? 162.613 123.462 128.827 1.00 177.22 ? 76  C   C OP2   1 
ATOM   7200 O "O5'" . C   C 2 76  ? 163.296 124.907 130.738 1.00 177.22 ? 76  C   C "O5'" 1 
ATOM   7201 C "C5'" . C   C 2 76  ? 163.206 126.086 131.523 1.00 177.22 ? 76  C   C "C5'" 1 
ATOM   7202 C "C4'" . C   C 2 76  ? 163.381 125.792 132.990 1.00 177.22 ? 76  C   C "C4'" 1 
ATOM   7203 O "O4'" . C   C 2 76  ? 162.247 125.038 133.494 1.00 177.22 ? 76  C   C "O4'" 1 
ATOM   7204 C "C3'" . C   C 2 76  ? 164.576 124.932 133.356 1.00 177.22 ? 76  C   C "C3'" 1 
ATOM   7205 O "O3'" . C   C 2 76  ? 165.796 125.650 133.362 1.00 177.22 ? 76  C   C "O3'" 1 
ATOM   7206 C "C2'" . C   C 2 76  ? 164.176 124.383 134.719 1.00 177.22 ? 76  C   C "C2'" 1 
ATOM   7207 O "O2'" . C   C 2 76  ? 164.368 125.362 135.729 1.00 177.22 ? 76  C   C "O2'" 1 
ATOM   7208 C "C1'" . C   C 2 76  ? 162.672 124.174 134.530 1.00 177.22 ? 76  C   C "C1'" 1 
ATOM   7209 N N1    . C   C 2 76  ? 162.342 122.774 134.168 1.00 177.22 ? 76  C   C N1    1 
ATOM   7210 C C2    . C   C 2 76  ? 162.412 121.792 135.164 1.00 177.22 ? 76  C   C C2    1 
ATOM   7211 O O2    . C   C 2 76  ? 162.750 122.124 136.309 1.00 177.22 ? 76  C   C O2    1 
ATOM   7212 N N3    . C   C 2 76  ? 162.116 120.507 134.859 1.00 177.22 ? 76  C   C N3    1 
ATOM   7213 C C4    . C   C 2 76  ? 161.759 120.186 133.615 1.00 177.22 ? 76  C   C C4    1 
ATOM   7214 N N4    . C   C 2 76  ? 161.474 118.907 133.355 1.00 177.22 ? 76  C   C N4    1 
ATOM   7215 C C5    . C   C 2 76  ? 161.678 121.164 132.581 1.00 177.22 ? 76  C   C C5    1 
ATOM   7216 C C6    . C   C 2 76  ? 161.973 122.433 132.897 1.00 177.22 ? 76  C   C C6    1 
ATOM   7217 P P     . C   C 2 77  ? 167.166 124.906 132.976 1.00 197.27 ? 77  C   C P     1 
ATOM   7218 O OP1   . C   C 2 77  ? 168.214 125.939 132.780 1.00 197.27 ? 77  C   C OP1   1 
ATOM   7219 O OP2   . C   C 2 77  ? 166.873 123.943 131.884 1.00 197.27 ? 77  C   C OP2   1 
ATOM   7220 O "O5'" . C   C 2 77  ? 167.525 124.077 134.286 1.00 197.27 ? 77  C   C "O5'" 1 
ATOM   7221 C "C5'" . C   C 2 77  ? 167.599 124.721 135.548 1.00 197.27 ? 77  C   C "C5'" 1 
ATOM   7222 C "C4'" . C   C 2 77  ? 167.619 123.730 136.684 1.00 197.27 ? 77  C   C "C4'" 1 
ATOM   7223 O "O4'" . C   C 2 77  ? 166.350 123.031 136.773 1.00 197.27 ? 77  C   C "O4'" 1 
ATOM   7224 C "C3'" . C   C 2 77  ? 168.638 122.611 136.579 1.00 197.27 ? 77  C   C "C3'" 1 
ATOM   7225 O "O3'" . C   C 2 77  ? 169.951 123.022 136.913 1.00 197.27 ? 77  C   C "O3'" 1 
ATOM   7226 C "C2'" . C   C 2 77  ? 168.064 121.561 137.520 1.00 197.27 ? 77  C   C "C2'" 1 
ATOM   7227 O "O2'" . C   C 2 77  ? 168.337 121.896 138.872 1.00 197.27 ? 77  C   C "O2'" 1 
ATOM   7228 C "C1'" . C   C 2 77  ? 166.561 121.726 137.276 1.00 197.27 ? 77  C   C "C1'" 1 
ATOM   7229 N N1    . C   C 2 77  ? 166.045 120.733 136.305 1.00 197.27 ? 77  C   C N1    1 
ATOM   7230 C C2    . C   C 2 77  ? 165.904 119.406 136.728 1.00 197.27 ? 77  C   C C2    1 
ATOM   7231 O O2    . C   C 2 77  ? 166.211 119.108 137.891 1.00 197.27 ? 77  C   C O2    1 
ATOM   7232 N N3    . C   C 2 77  ? 165.438 118.475 135.866 1.00 197.27 ? 77  C   C N3    1 
ATOM   7233 C C4    . C   C 2 77  ? 165.116 118.827 134.622 1.00 197.27 ? 77  C   C C4    1 
ATOM   7234 N N4    . C   C 2 77  ? 164.659 117.876 133.803 1.00 197.27 ? 77  C   C N4    1 
ATOM   7235 C C5    . C   C 2 77  ? 165.249 120.170 134.162 1.00 197.27 ? 77  C   C C5    1 
ATOM   7236 C C6    . C   C 2 77  ? 165.712 121.083 135.027 1.00 197.27 ? 77  C   C C6    1 
ATOM   7237 P P     . C   C 2 78  ? 171.213 122.311 136.220 1.00 208.43 ? 78  C   C P     1 
ATOM   7238 O OP1   . C   C 2 78  ? 172.428 123.092 136.567 1.00 208.43 ? 78  C   C OP1   1 
ATOM   7239 O OP2   . C   C 2 78  ? 170.878 122.065 134.794 1.00 208.43 ? 78  C   C OP2   1 
ATOM   7240 O "O5'" . C   C 2 78  ? 171.305 120.902 136.956 1.00 208.43 ? 78  C   C "O5'" 1 
ATOM   7241 C "C5'" . C   C 2 78  ? 171.418 120.832 138.369 1.00 208.43 ? 78  C   C "C5'" 1 
ATOM   7242 C "C4'" . C   C 2 78  ? 171.285 119.418 138.872 1.00 208.43 ? 78  C   C "C4'" 1 
ATOM   7243 O "O4'" . C   C 2 78  ? 169.928 118.936 138.681 1.00 208.43 ? 78  C   C "O4'" 1 
ATOM   7244 C "C3'" . C   C 2 78  ? 172.137 118.375 138.173 1.00 208.43 ? 78  C   C "C3'" 1 
ATOM   7245 O "O3'" . C   C 2 78  ? 173.493 118.399 138.579 1.00 208.43 ? 78  C   C "O3'" 1 
ATOM   7246 C "C2'" . C   C 2 78  ? 171.408 117.083 138.515 1.00 208.43 ? 78  C   C "C2'" 1 
ATOM   7247 O "O2'" . C   C 2 78  ? 171.694 116.683 139.847 1.00 208.43 ? 78  C   C "O2'" 1 
ATOM   7248 C "C1'" . C   C 2 78  ? 169.947 117.540 138.450 1.00 208.43 ? 78  C   C "C1'" 1 
ATOM   7249 N N1    . C   C 2 78  ? 169.348 117.258 137.126 1.00 208.43 ? 78  C   C N1    1 
ATOM   7250 C C2    . C   C 2 78  ? 168.947 115.947 136.848 1.00 208.43 ? 78  C   C C2    1 
ATOM   7251 O O2    . C   C 2 78  ? 169.090 115.075 137.717 1.00 208.43 ? 78  C   C O2    1 
ATOM   7252 N N3    . C   C 2 78  ? 168.406 115.653 135.644 1.00 208.43 ? 78  C   C N3    1 
ATOM   7253 C C4    . C   C 2 78  ? 168.264 116.614 134.731 1.00 208.43 ? 78  C   C C4    1 
ATOM   7254 N N4    . C   C 2 78  ? 167.727 116.282 133.554 1.00 208.43 ? 78  C   C N4    1 
ATOM   7255 C C5    . C   C 2 78  ? 168.667 117.958 134.983 1.00 208.43 ? 78  C   C C5    1 
ATOM   7256 C C6    . C   C 2 78  ? 169.200 118.234 136.180 1.00 208.43 ? 78  C   C C6    1 
ATOM   7257 P P     . U   C 2 79  ? 174.631 118.854 137.538 1.00 215.30 ? 79  U   C P     1 
ATOM   7258 O OP1   . U   C 2 79  ? 175.831 119.262 138.313 1.00 215.30 ? 79  U   C OP1   1 
ATOM   7259 O OP2   . U   C 2 79  ? 174.020 119.805 136.576 1.00 215.30 ? 79  U   C OP2   1 
ATOM   7260 O "O5'" . U   C 2 79  ? 174.983 117.518 136.746 1.00 215.30 ? 79  U   C "O5'" 1 
ATOM   7261 C "C5'" . U   C 2 79  ? 175.516 116.393 137.428 1.00 215.30 ? 79  U   C "C5'" 1 
ATOM   7262 C "C4'" . U   C 2 79  ? 174.972 115.099 136.878 1.00 215.30 ? 79  U   C "C4'" 1 
ATOM   7263 O "O4'" . U   C 2 79  ? 173.529 115.184 136.750 1.00 215.30 ? 79  U   C "O4'" 1 
ATOM   7264 C "C3'" . U   C 2 79  ? 175.436 114.709 135.485 1.00 215.30 ? 79  U   C "C3'" 1 
ATOM   7265 O "O3'" . U   C 2 79  ? 176.727 114.125 135.475 1.00 215.30 ? 79  U   C "O3'" 1 
ATOM   7266 C "C2'" . U   C 2 79  ? 174.339 113.759 135.028 1.00 215.30 ? 79  U   C "C2'" 1 
ATOM   7267 O "O2'" . U   C 2 79  ? 174.517 112.479 135.611 1.00 215.30 ? 79  U   C "O2'" 1 
ATOM   7268 C "C1'" . U   C 2 79  ? 173.100 114.403 135.654 1.00 215.30 ? 79  U   C "C1'" 1 
ATOM   7269 N N1    . U   C 2 79  ? 172.375 115.264 134.693 1.00 215.30 ? 79  U   C N1    1 
ATOM   7270 C C2    . U   C 2 79  ? 171.471 114.639 133.856 1.00 215.30 ? 79  U   C C2    1 
ATOM   7271 O O2    . U   C 2 79  ? 171.257 113.440 133.891 1.00 215.30 ? 79  U   C O2    1 
ATOM   7272 N N3    . U   C 2 79  ? 170.821 115.469 132.978 1.00 215.30 ? 79  U   C N3    1 
ATOM   7273 C C4    . U   C 2 79  ? 170.984 116.832 132.852 1.00 215.30 ? 79  U   C C4    1 
ATOM   7274 O O4    . U   C 2 79  ? 170.324 117.444 132.011 1.00 215.30 ? 79  U   C O4    1 
ATOM   7275 C C5    . U   C 2 79  ? 171.939 117.405 133.753 1.00 215.30 ? 79  U   C C5    1 
ATOM   7276 C C6    . U   C 2 79  ? 172.587 116.621 134.621 1.00 215.30 ? 79  U   C C6    1 
ATOM   7277 P P     . U   C 2 80  ? 177.575 114.060 134.111 1.00 220.62 ? 80  U   C P     1 
ATOM   7278 O OP1   . U   C 2 80  ? 178.987 113.766 134.464 1.00 220.62 ? 80  U   C OP1   1 
ATOM   7279 O OP2   . U   C 2 80  ? 177.254 115.272 133.314 1.00 220.62 ? 80  U   C OP2   1 
ATOM   7280 O "O5'" . U   C 2 80  ? 176.984 112.793 133.345 1.00 220.62 ? 80  U   C "O5'" 1 
ATOM   7281 C "C5'" . U   C 2 80  ? 177.479 112.420 132.067 1.00 220.62 ? 80  U   C "C5'" 1 
ATOM   7282 C "C4'" . U   C 2 80  ? 177.354 110.935 131.832 1.00 220.62 ? 80  U   C "C4'" 1 
ATOM   7283 O "O4'" . U   C 2 80  ? 177.997 110.212 132.913 1.00 220.62 ? 80  U   C "O4'" 1 
ATOM   7284 C "C3'" . U   C 2 80  ? 175.939 110.377 131.802 1.00 220.62 ? 80  U   C "C3'" 1 
ATOM   7285 O "O3'" . U   C 2 80  ? 175.309 110.554 130.544 1.00 220.62 ? 80  U   C "O3'" 1 
ATOM   7286 C "C2'" . U   C 2 80  ? 176.147 108.914 132.172 1.00 220.62 ? 80  U   C "C2'" 1 
ATOM   7287 O "O2'" . U   C 2 80  ? 176.584 108.169 131.044 1.00 220.62 ? 80  U   C "O2'" 1 
ATOM   7288 C "C1'" . U   C 2 80  ? 177.305 109.008 133.168 1.00 220.62 ? 80  U   C "C1'" 1 
ATOM   7289 N N1    . U   C 2 80  ? 176.843 109.013 134.575 1.00 220.62 ? 80  U   C N1    1 
ATOM   7290 C C2    . U   C 2 80  ? 176.457 107.807 135.132 1.00 220.62 ? 80  U   C C2    1 
ATOM   7291 O O2    . U   C 2 80  ? 176.474 106.754 134.518 1.00 220.62 ? 80  U   C O2    1 
ATOM   7292 N N3    . U   C 2 80  ? 176.044 107.878 136.440 1.00 220.62 ? 80  U   C N3    1 
ATOM   7293 C C4    . U   C 2 80  ? 175.983 109.006 137.232 1.00 220.62 ? 80  U   C C4    1 
ATOM   7294 O O4    . U   C 2 80  ? 175.588 108.908 138.395 1.00 220.62 ? 80  U   C O4    1 
ATOM   7295 C C5    . U   C 2 80  ? 176.403 110.211 136.585 1.00 220.62 ? 80  U   C C5    1 
ATOM   7296 C C6    . U   C 2 80  ? 176.809 110.173 135.312 1.00 220.62 ? 80  U   C C6    1 
ATOM   7297 P P     . A   C 2 81  ? 173.772 111.017 130.460 1.00 220.05 ? 81  A   C P     1 
ATOM   7298 O OP1   . A   C 2 81  ? 173.440 111.252 129.032 1.00 220.05 ? 81  A   C OP1   1 
ATOM   7299 O OP2   . A   C 2 81  ? 173.567 112.106 131.449 1.00 220.05 ? 81  A   C OP2   1 
ATOM   7300 O "O5'" . A   C 2 81  ? 172.952 109.743 130.953 1.00 220.05 ? 81  A   C "O5'" 1 
ATOM   7301 C "C5'" . A   C 2 81  ? 173.015 108.503 130.252 1.00 220.05 ? 81  A   C "C5'" 1 
ATOM   7302 C "C4'" . A   C 2 81  ? 171.766 107.681 130.466 1.00 220.05 ? 81  A   C "C4'" 1 
ATOM   7303 O "O4'" . A   C 2 81  ? 171.422 107.711 131.878 1.00 220.05 ? 81  A   C "O4'" 1 
ATOM   7304 C "C3'" . A   C 2 81  ? 170.531 108.176 129.721 1.00 220.05 ? 81  A   C "C3'" 1 
ATOM   7305 O "O3'" . A   C 2 81  ? 169.688 107.068 129.411 1.00 220.05 ? 81  A   C "O3'" 1 
ATOM   7306 C "C2'" . A   C 2 81  ? 169.849 109.059 130.758 1.00 220.05 ? 81  A   C "C2'" 1 
ATOM   7307 O "O2'" . A   C 2 81  ? 168.461 109.231 130.562 1.00 220.05 ? 81  A   C "O2'" 1 
ATOM   7308 C "C1'" . A   C 2 81  ? 170.149 108.308 132.053 1.00 220.05 ? 81  A   C "C1'" 1 
ATOM   7309 N N9    . A   C 2 81  ? 170.204 109.182 133.229 1.00 220.05 ? 81  A   C N9    1 
ATOM   7310 C C8    . A   C 2 81  ? 169.137 109.815 133.813 1.00 220.05 ? 81  A   C C8    1 
ATOM   7311 N N7    . A   C 2 81  ? 169.455 110.568 134.836 1.00 220.05 ? 81  A   C N7    1 
ATOM   7312 C C5    . A   C 2 81  ? 170.831 110.436 134.927 1.00 220.05 ? 81  A   C C5    1 
ATOM   7313 C C6    . A   C 2 81  ? 171.768 110.990 135.814 1.00 220.05 ? 81  A   C C6    1 
ATOM   7314 N N6    . A   C 2 81  ? 171.440 111.816 136.811 1.00 220.05 ? 81  A   C N6    1 
ATOM   7315 N N1    . A   C 2 81  ? 173.067 110.664 135.642 1.00 220.05 ? 81  A   C N1    1 
ATOM   7316 C C2    . A   C 2 81  ? 173.390 109.835 134.643 1.00 220.05 ? 81  A   C C2    1 
ATOM   7317 N N3    . A   C 2 81  ? 172.599 109.253 133.747 1.00 220.05 ? 81  A   C N3    1 
ATOM   7318 C C4    . A   C 2 81  ? 171.313 109.598 133.937 1.00 220.05 ? 81  A   C C4    1 
ATOM   7319 P P     . G   C 2 82  ? 168.772 107.093 128.091 1.00 217.47 ? 82  G   C P     1 
ATOM   7320 O OP1   . G   C 2 82  ? 169.602 106.642 126.945 1.00 217.47 ? 82  G   C OP1   1 
ATOM   7321 O OP2   . G   C 2 82  ? 168.086 108.408 128.028 1.00 217.47 ? 82  G   C OP2   1 
ATOM   7322 O "O5'" . G   C 2 82  ? 167.671 105.976 128.371 1.00 217.47 ? 82  G   C "O5'" 1 
ATOM   7323 C "C5'" . G   C 2 82  ? 166.995 105.915 129.618 1.00 217.47 ? 82  G   C "C5'" 1 
ATOM   7324 C "C4'" . G   C 2 82  ? 167.321 104.643 130.357 1.00 217.47 ? 82  G   C "C4'" 1 
ATOM   7325 O "O4'" . G   C 2 82  ? 168.687 104.695 130.845 1.00 217.47 ? 82  G   C "O4'" 1 
ATOM   7326 C "C3'" . G   C 2 82  ? 166.500 104.364 131.605 1.00 217.47 ? 82  G   C "C3'" 1 
ATOM   7327 O "O3'" . G   C 2 82  ? 165.223 103.818 131.323 1.00 217.47 ? 82  G   C "O3'" 1 
ATOM   7328 C "C2'" . G   C 2 82  ? 167.405 103.427 132.395 1.00 217.47 ? 82  G   C "C2'" 1 
ATOM   7329 O "O2'" . G   C 2 82  ? 167.329 102.105 131.882 1.00 217.47 ? 82  G   C "O2'" 1 
ATOM   7330 C "C1'" . G   C 2 82  ? 168.788 103.994 132.067 1.00 217.47 ? 82  G   C "C1'" 1 
ATOM   7331 N N9    . G   C 2 82  ? 169.278 104.911 133.116 1.00 217.47 ? 82  G   C N9    1 
ATOM   7332 C C8    . G   C 2 82  ? 168.534 105.750 133.912 1.00 217.47 ? 82  G   C C8    1 
ATOM   7333 N N7    . G   C 2 82  ? 169.256 106.435 134.756 1.00 217.47 ? 82  G   C N7    1 
ATOM   7334 C C5    . G   C 2 82  ? 170.557 106.021 134.509 1.00 217.47 ? 82  G   C C5    1 
ATOM   7335 C C6    . G   C 2 82  ? 171.778 106.417 135.114 1.00 217.47 ? 82  G   C C6    1 
ATOM   7336 O O6    . G   C 2 82  ? 171.958 107.238 136.022 1.00 217.47 ? 82  G   C O6    1 
ATOM   7337 N N1    . G   C 2 82  ? 172.863 105.749 134.558 1.00 217.47 ? 82  G   C N1    1 
ATOM   7338 C C2    . G   C 2 82  ? 172.787 104.820 133.549 1.00 217.47 ? 82  G   C C2    1 
ATOM   7339 N N2    . G   C 2 82  ? 173.949 104.285 133.149 1.00 217.47 ? 82  G   C N2    1 
ATOM   7340 N N3    . G   C 2 82  ? 171.656 104.443 132.976 1.00 217.47 ? 82  G   C N3    1 
ATOM   7341 C C4    . G   C 2 82  ? 170.587 105.081 133.500 1.00 217.47 ? 82  G   C C4    1 
ATOM   7342 P P     . G   C 2 83  ? 163.941 104.302 132.161 1.00 207.61 ? 83  G   C P     1 
ATOM   7343 O OP1   . G   C 2 83  ? 163.203 103.095 132.611 1.00 207.61 ? 83  G   C OP1   1 
ATOM   7344 O OP2   . G   C 2 83  ? 163.237 105.341 131.368 1.00 207.61 ? 83  G   C OP2   1 
ATOM   7345 O "O5'" . G   C 2 83  ? 164.571 105.004 133.446 1.00 207.61 ? 83  G   C "O5'" 1 
ATOM   7346 C "C5'" . G   C 2 83  ? 163.774 105.805 134.305 1.00 207.61 ? 83  G   C "C5'" 1 
ATOM   7347 C "C4'" . G   C 2 83  ? 164.584 106.361 135.449 1.00 207.61 ? 83  G   C "C4'" 1 
ATOM   7348 O "O4'" . G   C 2 83  ? 165.775 107.012 134.937 1.00 207.61 ? 83  G   C "O4'" 1 
ATOM   7349 C "C3'" . G   C 2 83  ? 163.905 107.433 136.286 1.00 207.61 ? 83  G   C "C3'" 1 
ATOM   7350 O "O3'" . G   C 2 83  ? 163.025 106.895 137.257 1.00 207.61 ? 83  G   C "O3'" 1 
ATOM   7351 C "C2'" . G   C 2 83  ? 165.084 108.190 136.884 1.00 207.61 ? 83  G   C "C2'" 1 
ATOM   7352 O "O2'" . G   C 2 83  ? 165.618 107.488 137.997 1.00 207.61 ? 83  G   C "O2'" 1 
ATOM   7353 C "C1'" . G   C 2 83  ? 166.099 108.127 135.741 1.00 207.61 ? 83  G   C "C1'" 1 
ATOM   7354 N N9    . G   C 2 83  ? 166.078 109.338 134.899 1.00 207.61 ? 83  G   C N9    1 
ATOM   7355 C C8    . G   C 2 83  ? 165.729 109.412 133.572 1.00 207.61 ? 83  G   C C8    1 
ATOM   7356 N N7    . G   C 2 83  ? 165.816 110.620 133.085 1.00 207.61 ? 83  G   C N7    1 
ATOM   7357 C C5    . G   C 2 83  ? 166.251 111.392 134.154 1.00 207.61 ? 83  G   C C5    1 
ATOM   7358 C C6    . G   C 2 83  ? 166.526 112.783 134.231 1.00 207.61 ? 83  G   C C6    1 
ATOM   7359 O O6    . G   C 2 83  ? 166.438 113.642 133.345 1.00 207.61 ? 83  G   C O6    1 
ATOM   7360 N N1    . G   C 2 83  ? 166.945 113.151 135.504 1.00 207.61 ? 83  G   C N1    1 
ATOM   7361 C C2    . G   C 2 83  ? 167.084 112.293 136.568 1.00 207.61 ? 83  G   C C2    1 
ATOM   7362 N N2    . G   C 2 83  ? 167.500 112.846 137.714 1.00 207.61 ? 83  G   C N2    1 
ATOM   7363 N N3    . G   C 2 83  ? 166.832 110.996 136.510 1.00 207.61 ? 83  G   C N3    1 
ATOM   7364 C C4    . G   C 2 83  ? 166.419 110.616 135.282 1.00 207.61 ? 83  G   C C4    1 
ATOM   7365 P P     . G   C 2 84  ? 161.711 107.707 137.699 1.00 197.99 ? 84  G   C P     1 
ATOM   7366 O OP1   . G   C 2 84  ? 160.863 106.800 138.512 1.00 197.99 ? 84  G   C OP1   1 
ATOM   7367 O OP2   . G   C 2 84  ? 161.144 108.358 136.490 1.00 197.99 ? 84  G   C OP2   1 
ATOM   7368 O "O5'" . G   C 2 84  ? 162.269 108.850 138.658 1.00 197.99 ? 84  G   C "O5'" 1 
ATOM   7369 C "C5'" . G   C 2 84  ? 162.934 108.524 139.869 1.00 197.99 ? 84  G   C "C5'" 1 
ATOM   7370 C "C4'" . G   C 2 84  ? 163.486 109.754 140.543 1.00 197.99 ? 84  G   C "C4'" 1 
ATOM   7371 O "O4'" . G   C 2 84  ? 164.549 110.322 139.737 1.00 197.99 ? 84  G   C "O4'" 1 
ATOM   7372 C "C3'" . G   C 2 84  ? 162.509 110.904 140.728 1.00 197.99 ? 84  G   C "C3'" 1 
ATOM   7373 O "O3'" . G   C 2 84  ? 161.668 110.734 141.856 1.00 197.99 ? 84  G   C "O3'" 1 
ATOM   7374 C "C2'" . G   C 2 84  ? 163.430 112.112 140.829 1.00 197.99 ? 84  G   C "C2'" 1 
ATOM   7375 O "O2'" . G   C 2 84  ? 163.990 112.209 142.130 1.00 197.99 ? 84  G   C "O2'" 1 
ATOM   7376 C "C1'" . G   C 2 84  ? 164.542 111.730 139.852 1.00 197.99 ? 84  G   C "C1'" 1 
ATOM   7377 N N9    . G   C 2 84  ? 164.339 112.314 138.513 1.00 197.99 ? 84  G   C N9    1 
ATOM   7378 C C8    . G   C 2 84  ? 163.999 111.651 137.358 1.00 197.99 ? 84  G   C C8    1 
ATOM   7379 N N7    . G   C 2 84  ? 163.903 112.442 136.324 1.00 197.99 ? 84  G   C N7    1 
ATOM   7380 C C5    . G   C 2 84  ? 164.191 113.704 136.825 1.00 197.99 ? 84  G   C C5    1 
ATOM   7381 C C6    . G   C 2 84  ? 164.242 114.966 136.176 1.00 197.99 ? 84  G   C C6    1 
ATOM   7382 O O6    . G   C 2 84  ? 164.033 115.235 134.987 1.00 197.99 ? 84  G   C O6    1 
ATOM   7383 N N1    . G   C 2 84  ? 164.577 115.982 137.062 1.00 197.99 ? 84  G   C N1    1 
ATOM   7384 C C2    . G   C 2 84  ? 164.832 115.809 138.401 1.00 197.99 ? 84  G   C C2    1 
ATOM   7385 N N2    . G   C 2 84  ? 165.137 116.914 139.093 1.00 197.99 ? 84  G   C N2    1 
ATOM   7386 N N3    . G   C 2 84  ? 164.790 114.641 139.017 1.00 197.99 ? 84  G   C N3    1 
ATOM   7387 C C4    . G   C 2 84  ? 164.466 113.639 138.175 1.00 197.99 ? 84  G   C C4    1 
ATOM   7388 P P     . G   C 2 85  ? 160.186 111.354 141.861 1.00 185.09 ? 85  G   C P     1 
ATOM   7389 O OP1   . G   C 2 85  ? 159.458 110.791 143.026 1.00 185.09 ? 85  G   C OP1   1 
ATOM   7390 O OP2   . G   C 2 85  ? 159.619 111.203 140.497 1.00 185.09 ? 85  G   C OP2   1 
ATOM   7391 O "O5'" . G   C 2 85  ? 160.421 112.906 142.133 1.00 185.09 ? 85  G   C "O5'" 1 
ATOM   7392 C "C5'" . G   C 2 85  ? 161.074 113.344 143.315 1.00 185.09 ? 85  G   C "C5'" 1 
ATOM   7393 C "C4'" . G   C 2 85  ? 161.476 114.794 143.222 1.00 185.09 ? 85  G   C "C4'" 1 
ATOM   7394 O "O4'" . G   C 2 85  ? 162.412 114.980 142.131 1.00 185.09 ? 85  G   C "O4'" 1 
ATOM   7395 C "C3'" . G   C 2 85  ? 160.359 115.779 142.921 1.00 185.09 ? 85  G   C "C3'" 1 
ATOM   7396 O "O3'" . G   C 2 85  ? 159.608 116.117 144.074 1.00 185.09 ? 85  G   C "O3'" 1 
ATOM   7397 C "C2'" . G   C 2 85  ? 161.106 116.962 142.316 1.00 185.09 ? 85  G   C "C2'" 1 
ATOM   7398 O "O2'" . G   C 2 85  ? 161.671 117.773 143.334 1.00 185.09 ? 85  G   C "O2'" 1 
ATOM   7399 C "C1'" . G   C 2 85  ? 162.243 116.262 141.567 1.00 185.09 ? 85  G   C "C1'" 1 
ATOM   7400 N N9    . G   C 2 85  ? 161.987 116.126 140.119 1.00 185.09 ? 85  G   C N9    1 
ATOM   7401 C C8    . G   C 2 85  ? 161.766 114.966 139.415 1.00 185.09 ? 85  G   C C8    1 
ATOM   7402 N N7    . G   C 2 85  ? 161.593 115.166 138.136 1.00 185.09 ? 85  G   C N7    1 
ATOM   7403 C C5    . G   C 2 85  ? 161.705 116.541 137.981 1.00 185.09 ? 85  G   C C5    1 
ATOM   7404 C C6    . G   C 2 85  ? 161.612 117.352 136.817 1.00 185.09 ? 85  G   C C6    1 
ATOM   7405 O O6    . G   C 2 85  ? 161.396 117.008 135.648 1.00 185.09 ? 85  G   C O6    1 
ATOM   7406 N N1    . G   C 2 85  ? 161.793 118.698 137.114 1.00 185.09 ? 85  G   C N1    1 
ATOM   7407 C C2    . G   C 2 85  ? 162.038 119.201 138.369 1.00 185.09 ? 85  G   C C2    1 
ATOM   7408 N N2    . G   C 2 85  ? 162.185 120.530 138.467 1.00 185.09 ? 85  G   C N2    1 
ATOM   7409 N N3    . G   C 2 85  ? 162.129 118.457 139.458 1.00 185.09 ? 85  G   C N3    1 
ATOM   7410 C C4    . G   C 2 85  ? 161.957 117.145 139.195 1.00 185.09 ? 85  G   C C4    1 
ATOM   7411 P P     . U   C 2 86  ? 158.088 116.618 143.937 1.00 170.87 ? 86  U   C P     1 
ATOM   7412 O OP1   . U   C 2 86  ? 157.467 116.572 145.285 1.00 170.87 ? 86  U   C OP1   1 
ATOM   7413 O OP2   . U   C 2 86  ? 157.458 115.879 142.814 1.00 170.87 ? 86  U   C OP2   1 
ATOM   7414 O "O5'" . U   C 2 86  ? 158.222 118.145 143.507 1.00 170.87 ? 86  U   C "O5'" 1 
ATOM   7415 C "C5'" . U   C 2 86  ? 158.780 119.109 144.389 1.00 170.87 ? 86  U   C "C5'" 1 
ATOM   7416 C "C4'" . U   C 2 86  ? 158.827 120.471 143.747 1.00 170.87 ? 86  U   C "C4'" 1 
ATOM   7417 O "O4'" . U   C 2 86  ? 159.771 120.455 142.645 1.00 170.87 ? 86  U   C "O4'" 1 
ATOM   7418 C "C3'" . U   C 2 86  ? 157.525 120.945 143.117 1.00 170.87 ? 86  U   C "C3'" 1 
ATOM   7419 O "O3'" . U   C 2 86  ? 156.637 121.521 144.058 1.00 170.87 ? 86  U   C "O3'" 1 
ATOM   7420 C "C2'" . U   C 2 86  ? 158.000 121.920 142.050 1.00 170.87 ? 86  U   C "C2'" 1 
ATOM   7421 O "O2'" . U   C 2 86  ? 158.323 123.177 142.626 1.00 170.87 ? 86  U   C "O2'" 1 
ATOM   7422 C "C1'" . U   C 2 86  ? 159.295 121.258 141.586 1.00 170.87 ? 86  U   C "C1'" 1 
ATOM   7423 N N1    . U   C 2 86  ? 159.110 120.394 140.396 1.00 170.87 ? 86  U   C N1    1 
ATOM   7424 C C2    . U   C 2 86  ? 159.062 120.976 139.142 1.00 170.87 ? 86  U   C C2    1 
ATOM   7425 O O2    . U   C 2 86  ? 159.143 122.180 138.967 1.00 170.87 ? 86  U   C O2    1 
ATOM   7426 N N3    . U   C 2 86  ? 158.908 120.092 138.098 1.00 170.87 ? 86  U   C N3    1 
ATOM   7427 C C4    . U   C 2 86  ? 158.806 118.716 138.182 1.00 170.87 ? 86  U   C C4    1 
ATOM   7428 O O4    . U   C 2 86  ? 158.671 118.036 137.165 1.00 170.87 ? 86  U   C O4    1 
ATOM   7429 C C5    . U   C 2 86  ? 158.871 118.195 139.509 1.00 170.87 ? 86  U   C C5    1 
ATOM   7430 C C6    . U   C 2 86  ? 159.021 119.031 140.537 1.00 170.87 ? 86  U   C C6    1 
ATOM   7431 P P     . U   C 2 87  ? 155.050 121.457 143.818 1.00 148.53 ? 87  U   C P     1 
ATOM   7432 O OP1   . U   C 2 87  ? 154.382 121.977 145.038 1.00 148.53 ? 87  U   C OP1   1 
ATOM   7433 O OP2   . U   C 2 87  ? 154.715 120.099 143.319 1.00 148.53 ? 87  U   C OP2   1 
ATOM   7434 O "O5'" . U   C 2 87  ? 154.796 122.496 142.637 1.00 148.53 ? 87  U   C "O5'" 1 
ATOM   7435 C "C5'" . U   C 2 87  ? 155.084 123.876 142.805 1.00 148.53 ? 87  U   C "C5'" 1 
ATOM   7436 C "C4'" . U   C 2 87  ? 155.054 124.611 141.489 1.00 148.53 ? 87  U   C "C4'" 1 
ATOM   7437 O "O4'" . U   C 2 87  ? 156.096 124.103 140.614 1.00 148.53 ? 87  U   C "O4'" 1 
ATOM   7438 C "C3'" . U   C 2 87  ? 153.783 124.457 140.671 1.00 148.53 ? 87  U   C "C3'" 1 
ATOM   7439 O "O3'" . U   C 2 87  ? 152.733 125.299 141.110 1.00 148.53 ? 87  U   C "O3'" 1 
ATOM   7440 C "C2'" . U   C 2 87  ? 154.262 124.758 139.257 1.00 148.53 ? 87  U   C "C2'" 1 
ATOM   7441 O "O2'" . U   C 2 87  ? 154.403 126.158 139.064 1.00 148.53 ? 87  U   C "O2'" 1 
ATOM   7442 C "C1'" . U   C 2 87  ? 155.655 124.131 139.272 1.00 148.53 ? 87  U   C "C1'" 1 
ATOM   7443 N N1    . U   C 2 87  ? 155.649 122.746 138.746 1.00 148.53 ? 87  U   C N1    1 
ATOM   7444 C C2    . U   C 2 87  ? 155.651 122.565 137.375 1.00 148.53 ? 87  U   C C2    1 
ATOM   7445 O O2    . U   C 2 87  ? 155.658 123.495 136.586 1.00 148.53 ? 87  U   C O2    1 
ATOM   7446 N N3    . U   C 2 87  ? 155.646 121.255 136.959 1.00 148.53 ? 87  U   C N3    1 
ATOM   7447 C C4    . U   C 2 87  ? 155.640 120.133 137.767 1.00 148.53 ? 87  U   C C4    1 
ATOM   7448 O O4    . U   C 2 87  ? 155.636 119.007 137.270 1.00 148.53 ? 87  U   C O4    1 
ATOM   7449 C C5    . U   C 2 87  ? 155.637 120.404 139.169 1.00 148.53 ? 87  U   C C5    1 
ATOM   7450 C C6    . U   C 2 87  ? 155.641 121.667 139.596 1.00 148.53 ? 87  U   C C6    1 
ATOM   7451 P P     . C   C 2 88  ? 151.234 124.731 141.205 1.00 112.75 ? 88  C   C P     1 
ATOM   7452 O OP1   . C   C 2 88  ? 150.381 125.784 141.812 1.00 112.75 ? 88  C   C OP1   1 
ATOM   7453 O OP2   . C   C 2 88  ? 151.292 123.384 141.826 1.00 112.75 ? 88  C   C OP2   1 
ATOM   7454 O "O5'" . C   C 2 88  ? 150.793 124.558 139.684 1.00 112.75 ? 88  C   C "O5'" 1 
ATOM   7455 C "C5'" . C   C 2 88  ? 150.765 125.675 138.808 1.00 112.75 ? 88  C   C "C5'" 1 
ATOM   7456 C "C4'" . C   C 2 88  ? 150.800 125.251 137.361 1.00 112.75 ? 88  C   C "C4'" 1 
ATOM   7457 O "O4'" . C   C 2 88  ? 151.967 124.429 137.112 1.00 112.75 ? 88  C   C "O4'" 1 
ATOM   7458 C "C3'" . C   C 2 88  ? 149.641 124.394 136.884 1.00 112.75 ? 88  C   C "C3'" 1 
ATOM   7459 O "O3'" . C   C 2 88  ? 148.482 125.155 136.593 1.00 112.75 ? 88  C   C "O3'" 1 
ATOM   7460 C "C2'" . C   C 2 88  ? 150.228 123.689 135.667 1.00 112.75 ? 88  C   C "C2'" 1 
ATOM   7461 O "O2'" . C   C 2 88  ? 150.210 124.545 134.535 1.00 112.75 ? 88  C   C "O2'" 1 
ATOM   7462 C "C1'" . C   C 2 88  ? 151.684 123.488 136.098 1.00 112.75 ? 88  C   C "C1'" 1 
ATOM   7463 N N1    . C   C 2 88  ? 151.942 122.123 136.611 1.00 112.75 ? 88  C   C N1    1 
ATOM   7464 C C2    . C   C 2 88  ? 152.379 121.161 135.698 1.00 112.75 ? 88  C   C C2    1 
ATOM   7465 O O2    . C   C 2 88  ? 152.537 121.518 134.520 1.00 112.75 ? 88  C   C O2    1 
ATOM   7466 N N3    . C   C 2 88  ? 152.634 119.903 136.124 1.00 112.75 ? 88  C   C N3    1 
ATOM   7467 C C4    . C   C 2 88  ? 152.453 119.592 137.408 1.00 112.75 ? 88  C   C C4    1 
ATOM   7468 N N4    . C   C 2 88  ? 152.711 118.340 137.789 1.00 112.75 ? 88  C   C N4    1 
ATOM   7469 C C5    . C   C 2 88  ? 152.004 120.551 138.361 1.00 112.75 ? 88  C   C C5    1 
ATOM   7470 C C6    . C   C 2 88  ? 151.761 121.794 137.925 1.00 112.75 ? 88  C   C C6    1 
ATOM   7471 P P     . G   C 2 89  ? 147.027 124.592 136.972 1.00 88.54  ? 89  G   C P     1 
ATOM   7472 O OP1   . G   C 2 89  ? 146.037 125.672 136.737 1.00 88.54  ? 89  G   C OP1   1 
ATOM   7473 O OP2   . G   C 2 89  ? 147.115 123.951 138.309 1.00 88.54  ? 89  G   C OP2   1 
ATOM   7474 O "O5'" . G   C 2 89  ? 146.769 123.449 135.895 1.00 88.54  ? 89  G   C "O5'" 1 
ATOM   7475 C "C5'" . G   C 2 89  ? 146.768 123.742 134.507 1.00 88.54  ? 89  G   C "C5'" 1 
ATOM   7476 C "C4'" . G   C 2 89  ? 146.825 122.481 133.686 1.00 88.54  ? 89  G   C "C4'" 1 
ATOM   7477 O "O4'" . G   C 2 89  ? 148.133 121.869 133.825 1.00 88.54  ? 89  G   C "O4'" 1 
ATOM   7478 C "C3'" . G   C 2 89  ? 145.856 121.384 134.098 1.00 88.54  ? 89  G   C "C3'" 1 
ATOM   7479 O "O3'" . G   C 2 89  ? 144.553 121.576 133.574 1.00 88.54  ? 89  G   C "O3'" 1 
ATOM   7480 C "C2'" . G   C 2 89  ? 146.541 120.124 133.586 1.00 88.54  ? 89  G   C "C2'" 1 
ATOM   7481 O "O2'" . G   C 2 89  ? 146.337 119.974 132.189 1.00 88.54  ? 89  G   C "O2'" 1 
ATOM   7482 C "C1'" . G   C 2 89  ? 148.012 120.464 133.824 1.00 88.54  ? 89  G   C "C1'" 1 
ATOM   7483 N N9    . G   C 2 89  ? 148.496 119.955 135.120 1.00 88.54  ? 89  G   C N9    1 
ATOM   7484 C C8    . G   C 2 89  ? 148.588 120.647 136.301 1.00 88.54  ? 89  G   C C8    1 
ATOM   7485 N N7    . G   C 2 89  ? 149.056 119.924 137.281 1.00 88.54  ? 89  G   C N7    1 
ATOM   7486 C C5    . G   C 2 89  ? 149.288 118.682 136.712 1.00 88.54  ? 89  G   C C5    1 
ATOM   7487 C C6    . G   C 2 89  ? 149.795 117.488 137.282 1.00 88.54  ? 89  G   C C6    1 
ATOM   7488 O O6    . G   C 2 89  ? 150.155 117.280 138.446 1.00 88.54  ? 89  G   C O6    1 
ATOM   7489 N N1    . G   C 2 89  ? 149.867 116.464 136.347 1.00 88.54  ? 89  G   C N1    1 
ATOM   7490 C C2    . G   C 2 89  ? 149.497 116.576 135.032 1.00 88.54  ? 89  G   C C2    1 
ATOM   7491 N N2    . G   C 2 89  ? 149.639 115.478 134.283 1.00 88.54  ? 89  G   C N2    1 
ATOM   7492 N N3    . G   C 2 89  ? 149.023 117.681 134.486 1.00 88.54  ? 89  G   C N3    1 
ATOM   7493 C C4    . G   C 2 89  ? 148.946 118.685 135.379 1.00 88.54  ? 89  G   C C4    1 
ATOM   7494 P P     . U   C 2 90  ? 143.380 122.166 134.502 1.00 72.90  ? 90  U   C P     1 
ATOM   7495 O OP1   . U   C 2 90  ? 142.453 122.933 133.633 1.00 72.90  ? 90  U   C OP1   1 
ATOM   7496 O OP2   . U   C 2 90  ? 143.996 122.825 135.680 1.00 72.90  ? 90  U   C OP2   1 
ATOM   7497 O "O5'" . U   C 2 90  ? 142.610 120.874 135.026 1.00 72.90  ? 90  U   C "O5'" 1 
ATOM   7498 C "C5'" . U   C 2 90  ? 143.139 120.093 136.086 1.00 72.90  ? 90  U   C "C5'" 1 
ATOM   7499 C "C4'" . U   C 2 90  ? 142.972 118.620 135.817 1.00 72.90  ? 90  U   C "C4'" 1 
ATOM   7500 O "O4'" . U   C 2 90  ? 143.646 117.852 136.846 1.00 72.90  ? 90  U   C "O4'" 1 
ATOM   7501 C "C3'" . U   C 2 90  ? 141.546 118.097 135.842 1.00 72.90  ? 90  U   C "C3'" 1 
ATOM   7502 O "O3'" . U   C 2 90  ? 140.853 118.342 134.631 1.00 72.90  ? 90  U   C "O3'" 1 
ATOM   7503 C "C2'" . U   C 2 90  ? 141.739 116.618 136.145 1.00 72.90  ? 90  U   C "C2'" 1 
ATOM   7504 O "O2'" . U   C 2 90  ? 142.119 115.913 134.973 1.00 72.90  ? 90  U   C "O2'" 1 
ATOM   7505 C "C1'" . U   C 2 90  ? 142.939 116.656 137.093 1.00 72.90  ? 90  U   C "C1'" 1 
ATOM   7506 N N1    . U   C 2 90  ? 142.537 116.630 138.516 1.00 72.90  ? 90  U   C N1    1 
ATOM   7507 C C2    . U   C 2 90  ? 142.212 115.407 139.064 1.00 72.90  ? 90  U   C C2    1 
ATOM   7508 O O2    . U   C 2 90  ? 142.239 114.369 138.426 1.00 72.90  ? 90  U   C O2    1 
ATOM   7509 N N3    . U   C 2 90  ? 141.851 115.445 140.387 1.00 72.90  ? 90  U   C N3    1 
ATOM   7510 C C4    . U   C 2 90  ? 141.786 116.557 141.200 1.00 72.90  ? 90  U   C C4    1 
ATOM   7511 O O4    . U   C 2 90  ? 141.442 116.429 142.376 1.00 72.90  ? 90  U   C O4    1 
ATOM   7512 C C5    . U   C 2 90  ? 142.142 117.785 140.558 1.00 72.90  ? 90  U   C C5    1 
ATOM   7513 C C6    . U   C 2 90  ? 142.497 117.779 139.270 1.00 72.90  ? 90  U   C C6    1 
ATOM   7514 P P     . G   C 2 91  ? 139.258 118.528 134.634 1.00 81.19  ? 91  G   C P     1 
ATOM   7515 O OP1   . G   C 2 91  ? 138.906 119.490 133.560 1.00 81.19  ? 91  G   C OP1   1 
ATOM   7516 O OP2   . G   C 2 91  ? 138.826 118.797 136.028 1.00 81.19  ? 91  G   C OP2   1 
ATOM   7517 O "O5'" . G   C 2 91  ? 138.702 117.095 134.219 1.00 81.19  ? 91  G   C "O5'" 1 
ATOM   7518 C "C5'" . G   C 2 91  ? 138.057 116.259 135.172 1.00 81.19  ? 91  G   C "C5'" 1 
ATOM   7519 C "C4'" . G   C 2 91  ? 136.558 116.346 135.050 1.00 81.19  ? 91  G   C "C4'" 1 
ATOM   7520 O "O4'" . G   C 2 91  ? 136.158 115.934 133.711 1.00 81.19  ? 91  G   C "O4'" 1 
ATOM   7521 C "C3'" . G   C 2 91  ? 135.761 115.468 136.016 1.00 81.19  ? 91  G   C "C3'" 1 
ATOM   7522 O "O3'" . G   C 2 91  ? 134.542 116.141 136.333 1.00 81.19  ? 91  G   C "O3'" 1 
ATOM   7523 C "C2'" . G   C 2 91  ? 135.457 114.244 135.159 1.00 81.19  ? 91  G   C "C2'" 1 
ATOM   7524 O "O2'" . G   C 2 91  ? 134.357 113.469 135.587 1.00 81.19  ? 91  G   C "O2'" 1 
ATOM   7525 C "C1'" . G   C 2 91  ? 135.204 114.896 133.809 1.00 81.19  ? 91  G   C "C1'" 1 
ATOM   7526 N N9    . G   C 2 91  ? 135.342 113.999 132.662 1.00 81.19  ? 91  G   C N9    1 
ATOM   7527 C C8    . G   C 2 91  ? 136.240 112.978 132.478 1.00 81.19  ? 91  G   C C8    1 
ATOM   7528 N N7    . G   C 2 91  ? 136.079 112.363 131.337 1.00 81.19  ? 91  G   C N7    1 
ATOM   7529 C C5    . G   C 2 91  ? 135.008 113.014 130.742 1.00 81.19  ? 91  G   C C5    1 
ATOM   7530 C C6    . G   C 2 91  ? 134.366 112.796 129.498 1.00 81.19  ? 91  G   C C6    1 
ATOM   7531 O O6    . G   C 2 91  ? 134.633 111.951 128.637 1.00 81.19  ? 91  G   C O6    1 
ATOM   7532 N N1    . G   C 2 91  ? 133.319 113.690 129.290 1.00 81.19  ? 91  G   C N1    1 
ATOM   7533 C C2    . G   C 2 91  ? 132.936 114.667 130.173 1.00 81.19  ? 91  G   C C2    1 
ATOM   7534 N N2    . G   C 2 91  ? 131.901 115.434 129.805 1.00 81.19  ? 91  G   C N2    1 
ATOM   7535 N N3    . G   C 2 91  ? 133.523 114.878 131.337 1.00 81.19  ? 91  G   C N3    1 
ATOM   7536 C C4    . G   C 2 91  ? 134.543 114.023 131.550 1.00 81.19  ? 91  G   C C4    1 
ATOM   7537 P P     . C   C 2 92  ? 133.612 115.655 137.552 1.00 84.67  ? 92  C   C P     1 
ATOM   7538 O OP1   . C   C 2 92  ? 133.501 116.787 138.506 1.00 84.67  ? 92  C   C OP1   1 
ATOM   7539 O OP2   . C   C 2 92  ? 134.093 114.336 138.035 1.00 84.67  ? 92  C   C OP2   1 
ATOM   7540 O "O5'" . C   C 2 92  ? 132.183 115.446 136.875 1.00 84.67  ? 92  C   C "O5'" 1 
ATOM   7541 C "C5'" . C   C 2 92  ? 131.348 116.560 136.600 1.00 84.67  ? 92  C   C "C5'" 1 
ATOM   7542 C "C4'" . C   C 2 92  ? 130.230 116.221 135.642 1.00 84.67  ? 92  C   C "C4'" 1 
ATOM   7543 O "O4'" . C   C 2 92  ? 130.754 115.967 134.316 1.00 84.67  ? 92  C   C "O4'" 1 
ATOM   7544 C "C3'" . C   C 2 92  ? 129.412 114.980 135.952 1.00 84.67  ? 92  C   C "C3'" 1 
ATOM   7545 O "O3'" . C   C 2 92  ? 128.451 115.198 136.969 1.00 84.67  ? 92  C   C "O3'" 1 
ATOM   7546 C "C2'" . C   C 2 92  ? 128.793 114.644 134.599 1.00 84.67  ? 92  C   C "C2'" 1 
ATOM   7547 O "O2'" . C   C 2 92  ? 127.648 115.448 134.356 1.00 84.67  ? 92  C   C "O2'" 1 
ATOM   7548 C "C1'" . C   C 2 92  ? 129.900 115.074 133.631 1.00 84.67  ? 92  C   C "C1'" 1 
ATOM   7549 N N1    . C   C 2 92  ? 130.688 113.929 133.117 1.00 84.67  ? 92  C   C N1    1 
ATOM   7550 C C2    . C   C 2 92  ? 130.333 113.399 131.873 1.00 84.67  ? 92  C   C C2    1 
ATOM   7551 O O2    . C   C 2 92  ? 129.385 113.915 131.266 1.00 84.67  ? 92  C   C O2    1 
ATOM   7552 N N3    . C   C 2 92  ? 131.029 112.354 131.368 1.00 84.67  ? 92  C   C N3    1 
ATOM   7553 C C4    . C   C 2 92  ? 132.041 111.840 132.065 1.00 84.67  ? 92  C   C C4    1 
ATOM   7554 N N4    . C   C 2 92  ? 132.708 110.810 131.541 1.00 84.67  ? 92  C   C N4    1 
ATOM   7555 C C5    . C   C 2 92  ? 132.421 112.357 133.337 1.00 84.67  ? 92  C   C C5    1 
ATOM   7556 C C6    . C   C 2 92  ? 131.727 113.393 133.822 1.00 84.67  ? 92  C   C C6    1 
ATOM   7557 P P     . A   C 2 93  ? 127.698 113.955 137.653 1.00 98.37  ? 93  A   C P     1 
ATOM   7558 O OP1   . A   C 2 93  ? 127.123 114.417 138.940 1.00 98.37  ? 93  A   C OP1   1 
ATOM   7559 O OP2   . A   C 2 93  ? 128.624 112.795 137.639 1.00 98.37  ? 93  A   C OP2   1 
ATOM   7560 O "O5'" . A   C 2 93  ? 126.493 113.635 136.661 1.00 98.37  ? 93  A   C "O5'" 1 
ATOM   7561 C "C5'" . A   C 2 93  ? 125.650 112.516 136.885 1.00 98.37  ? 93  A   C "C5'" 1 
ATOM   7562 C "C4'" . A   C 2 93  ? 124.864 112.150 135.652 1.00 98.37  ? 93  A   C "C4'" 1 
ATOM   7563 O "O4'" . A   C 2 93  ? 125.580 112.576 134.465 1.00 98.37  ? 93  A   C "O4'" 1 
ATOM   7564 C "C3'" . A   C 2 93  ? 124.635 110.662 135.439 1.00 98.37  ? 93  A   C "C3'" 1 
ATOM   7565 O "O3'" . A   C 2 93  ? 123.537 110.168 136.186 1.00 98.37  ? 93  A   C "O3'" 1 
ATOM   7566 C "C2'" . A   C 2 93  ? 124.443 110.558 133.932 1.00 98.37  ? 93  A   C "C2'" 1 
ATOM   7567 O "O2'" . A   C 2 93  ? 123.120 110.921 133.569 1.00 98.37  ? 93  A   C "O2'" 1 
ATOM   7568 C "C1'" . A   C 2 93  ? 125.397 111.640 133.425 1.00 98.37  ? 93  A   C "C1'" 1 
ATOM   7569 N N9    . A   C 2 93  ? 126.723 111.115 133.040 1.00 98.37  ? 93  A   C N9    1 
ATOM   7570 C C8    . A   C 2 93  ? 127.917 111.478 133.608 1.00 98.37  ? 93  A   C C8    1 
ATOM   7571 N N7    . A   C 2 93  ? 128.963 110.893 133.085 1.00 98.37  ? 93  A   C N7    1 
ATOM   7572 C C5    . A   C 2 93  ? 128.423 110.092 132.094 1.00 98.37  ? 93  A   C C5    1 
ATOM   7573 C C6    . A   C 2 93  ? 129.027 109.218 131.179 1.00 98.37  ? 93  A   C C6    1 
ATOM   7574 N N6    . A   C 2 93  ? 130.343 109.014 131.131 1.00 98.37  ? 93  A   C N6    1 
ATOM   7575 N N1    . A   C 2 93  ? 128.232 108.556 130.313 1.00 98.37  ? 93  A   C N1    1 
ATOM   7576 C C2    . A   C 2 93  ? 126.910 108.771 130.375 1.00 98.37  ? 93  A   C C2    1 
ATOM   7577 N N3    . A   C 2 93  ? 126.223 109.572 131.194 1.00 98.37  ? 93  A   C N3    1 
ATOM   7578 C C4    . A   C 2 93  ? 127.046 110.217 132.042 1.00 98.37  ? 93  A   C C4    1 
ATOM   7579 P P     . U   C 2 94  ? 123.672 108.803 137.021 1.00 122.94 ? 94  U   C P     1 
ATOM   7580 O OP1   . U   C 2 94  ? 122.619 108.800 138.068 1.00 122.94 ? 94  U   C OP1   1 
ATOM   7581 O OP2   . U   C 2 94  ? 125.095 108.644 137.412 1.00 122.94 ? 94  U   C OP2   1 
ATOM   7582 O "O5'" . U   C 2 94  ? 123.315 107.668 135.961 1.00 122.94 ? 94  U   C "O5'" 1 
ATOM   7583 C "C5'" . U   C 2 94  ? 122.046 107.640 135.325 1.00 122.94 ? 94  U   C "C5'" 1 
ATOM   7584 C "C4'" . U   C 2 94  ? 122.086 106.843 134.046 1.00 122.94 ? 94  U   C "C4'" 1 
ATOM   7585 O "O4'" . U   C 2 94  ? 123.026 107.449 133.121 1.00 122.94 ? 94  U   C "O4'" 1 
ATOM   7586 C "C3'" . U   C 2 94  ? 122.563 105.405 134.171 1.00 122.94 ? 94  U   C "C3'" 1 
ATOM   7587 O "O3'" . U   C 2 94  ? 121.540 104.523 134.602 1.00 122.94 ? 94  U   C "O3'" 1 
ATOM   7588 C "C2'" . U   C 2 94  ? 123.077 105.099 132.771 1.00 122.94 ? 94  U   C "C2'" 1 
ATOM   7589 O "O2'" . U   C 2 94  ? 122.000 104.800 131.896 1.00 122.94 ? 94  U   C "O2'" 1 
ATOM   7590 C "C1'" . U   C 2 94  ? 123.668 106.448 132.361 1.00 122.94 ? 94  U   C "C1'" 1 
ATOM   7591 N N1    . U   C 2 94  ? 125.126 106.531 132.607 1.00 122.94 ? 94  U   C N1    1 
ATOM   7592 C C2    . U   C 2 94  ? 125.977 105.808 131.792 1.00 122.94 ? 94  U   C C2    1 
ATOM   7593 O O2    . U   C 2 94  ? 125.590 105.090 130.886 1.00 122.94 ? 94  U   C O2    1 
ATOM   7594 N N3    . U   C 2 94  ? 127.312 105.948 132.083 1.00 122.94 ? 94  U   C N3    1 
ATOM   7595 C C4    . U   C 2 94  ? 127.871 106.724 133.075 1.00 122.94 ? 94  U   C C4    1 
ATOM   7596 O O4    . U   C 2 94  ? 129.094 106.747 133.211 1.00 122.94 ? 94  U   C O4    1 
ATOM   7597 C C5    . U   C 2 94  ? 126.927 107.445 133.869 1.00 122.94 ? 94  U   C C5    1 
ATOM   7598 C C6    . U   C 2 94  ? 125.623 107.326 133.611 1.00 122.94 ? 94  U   C C6    1 
ATOM   7599 P P     . G   C 2 95  ? 121.908 103.167 135.382 1.00 170.82 ? 95  G   C P     1 
ATOM   7600 O OP1   . G   C 2 95  ? 120.654 102.602 135.940 1.00 170.82 ? 95  G   C OP1   1 
ATOM   7601 O OP2   . G   C 2 95  ? 123.049 103.457 136.288 1.00 170.82 ? 95  G   C OP2   1 
ATOM   7602 O "O5'" . G   C 2 95  ? 122.426 102.186 134.238 1.00 170.82 ? 95  G   C "O5'" 1 
ATOM   7603 C "C5'" . G   C 2 95  ? 121.600 101.842 133.129 1.00 170.82 ? 95  G   C "C5'" 1 
ATOM   7604 C "C4'" . G   C 2 95  ? 122.425 101.411 131.942 1.00 170.82 ? 95  G   C "C4'" 1 
ATOM   7605 O "O4'" . G   C 2 95  ? 123.830 101.589 132.265 1.00 170.82 ? 95  G   C "O4'" 1 
ATOM   7606 C "C3'" . G   C 2 95  ? 122.263 99.947  131.540 1.00 170.82 ? 95  G   C "C3'" 1 
ATOM   7607 O "O3'" . G   C 2 95  ? 122.433 99.806  130.131 1.00 170.82 ? 95  G   C "O3'" 1 
ATOM   7608 C "C2'" . G   C 2 95  ? 123.420 99.269  132.262 1.00 170.82 ? 95  G   C "C2'" 1 
ATOM   7609 O "O2'" . G   C 2 95  ? 123.858 98.069  131.661 1.00 170.82 ? 95  G   C "O2'" 1 
ATOM   7610 C "C1'" . G   C 2 95  ? 124.501 100.344 132.208 1.00 170.82 ? 95  G   C "C1'" 1 
ATOM   7611 N N9    . G   C 2 95  ? 125.424 100.280 133.342 1.00 170.82 ? 95  G   C N9    1 
ATOM   7612 C C8    . G   C 2 95  ? 125.398 101.062 134.471 1.00 170.82 ? 95  G   C C8    1 
ATOM   7613 N N7    . G   C 2 95  ? 126.348 100.771 135.315 1.00 170.82 ? 95  G   C N7    1 
ATOM   7614 C C5    . G   C 2 95  ? 127.042 99.735  134.705 1.00 170.82 ? 95  G   C C5    1 
ATOM   7615 C C6    . G   C 2 95  ? 128.175 99.008  135.146 1.00 170.82 ? 95  G   C C6    1 
ATOM   7616 O O6    . G   C 2 95  ? 128.808 99.146  136.197 1.00 170.82 ? 95  G   C O6    1 
ATOM   7617 N N1    . G   C 2 95  ? 128.556 98.041  134.221 1.00 170.82 ? 95  G   C N1    1 
ATOM   7618 C C2    . G   C 2 95  ? 127.927 97.805  133.024 1.00 170.82 ? 95  G   C C2    1 
ATOM   7619 N N2    . G   C 2 95  ? 128.445 96.828  132.266 1.00 170.82 ? 95  G   C N2    1 
ATOM   7620 N N3    . G   C 2 95  ? 126.869 98.476  132.600 1.00 170.82 ? 95  G   C N3    1 
ATOM   7621 C C4    . G   C 2 95  ? 126.487 99.422  133.483 1.00 170.82 ? 95  G   C C4    1 
ATOM   7622 P P     . G   C 2 96  ? 121.532 98.755  129.314 1.00 196.94 ? 96  G   C P     1 
ATOM   7623 O OP1   . G   C 2 96  ? 121.930 98.828  127.885 1.00 196.94 ? 96  G   C OP1   1 
ATOM   7624 O OP2   . G   C 2 96  ? 120.112 98.974  129.692 1.00 196.94 ? 96  G   C OP2   1 
ATOM   7625 O "O5'" . G   C 2 96  ? 121.980 97.331  129.876 1.00 196.94 ? 96  G   C "O5'" 1 
ATOM   7626 C "C5'" . G   C 2 96  ? 122.423 96.309  128.994 1.00 196.94 ? 96  G   C "C5'" 1 
ATOM   7627 C "C4'" . G   C 2 96  ? 122.618 94.990  129.703 1.00 196.94 ? 96  G   C "C4'" 1 
ATOM   7628 O "O4'" . G   C 2 96  ? 123.647 95.114  130.718 1.00 196.94 ? 96  G   C "O4'" 1 
ATOM   7629 C "C3'" . G   C 2 96  ? 121.419 94.441  130.462 1.00 196.94 ? 96  G   C "C3'" 1 
ATOM   7630 O "O3'" . G   C 2 96  ? 120.487 93.773  129.626 1.00 196.94 ? 96  G   C "O3'" 1 
ATOM   7631 C "C2'" . G   C 2 96  ? 122.069 93.515  131.479 1.00 196.94 ? 96  G   C "C2'" 1 
ATOM   7632 O "O2'" . G   C 2 96  ? 122.433 92.288  130.867 1.00 196.94 ? 96  G   C "O2'" 1 
ATOM   7633 C "C1'" . G   C 2 96  ? 123.354 94.262  131.807 1.00 196.94 ? 96  G   C "C1'" 1 
ATOM   7634 N N9    . G   C 2 96  ? 123.264 95.073  133.034 1.00 196.94 ? 96  G   C N9    1 
ATOM   7635 C C8    . G   C 2 96  ? 122.419 96.124  133.296 1.00 196.94 ? 96  G   C C8    1 
ATOM   7636 N N7    . G   C 2 96  ? 122.621 96.660  134.468 1.00 196.94 ? 96  G   C N7    1 
ATOM   7637 C C5    . G   C 2 96  ? 123.663 95.918  135.007 1.00 196.94 ? 96  G   C C5    1 
ATOM   7638 C C6    . G   C 2 96  ? 124.325 96.034  136.253 1.00 196.94 ? 96  G   C C6    1 
ATOM   7639 O O6    . G   C 2 96  ? 124.101 96.815  137.181 1.00 196.94 ? 96  G   C O6    1 
ATOM   7640 N N1    . G   C 2 96  ? 125.321 95.069  136.407 1.00 196.94 ? 96  G   C N1    1 
ATOM   7641 C C2    . G   C 2 96  ? 125.667 94.133  135.458 1.00 196.94 ? 96  G   C C2    1 
ATOM   7642 N N2    . G   C 2 96  ? 126.662 93.288  135.799 1.00 196.94 ? 96  G   C N2    1 
ATOM   7643 N N3    . G   C 2 96  ? 125.056 94.019  134.289 1.00 196.94 ? 96  G   C N3    1 
ATOM   7644 C C4    . G   C 2 96  ? 124.078 94.939  134.133 1.00 196.94 ? 96  G   C C4    1 
ATOM   7645 P P     . G   C 2 97  ? 119.062 93.300  130.206 1.00 209.21 ? 97  G   C P     1 
ATOM   7646 O OP1   . G   C 2 97  ? 118.233 92.849  129.060 1.00 209.21 ? 97  G   C OP1   1 
ATOM   7647 O OP2   . G   C 2 97  ? 118.556 94.374  131.098 1.00 209.21 ? 97  G   C OP2   1 
ATOM   7648 O "O5'" . G   C 2 97  ? 119.389 92.025  131.110 1.00 209.21 ? 97  G   C "O5'" 1 
ATOM   7649 C "C5'" . G   C 2 97  ? 119.742 90.777  130.527 1.00 209.21 ? 97  G   C "C5'" 1 
ATOM   7650 C "C4'" . G   C 2 97  ? 120.494 89.895  131.498 1.00 209.21 ? 97  G   C "C4'" 1 
ATOM   7651 O "O4'" . G   C 2 97  ? 121.586 90.638  132.097 1.00 209.21 ? 97  G   C "O4'" 1 
ATOM   7652 C "C3'" . G   C 2 97  ? 119.703 89.374  132.686 1.00 209.21 ? 97  G   C "C3'" 1 
ATOM   7653 O "O3'" . G   C 2 97  ? 118.937 88.228  132.358 1.00 209.21 ? 97  G   C "O3'" 1 
ATOM   7654 C "C2'" . G   C 2 97  ? 120.789 89.102  133.723 1.00 209.21 ? 97  G   C "C2'" 1 
ATOM   7655 O "O2'" . G   C 2 97  ? 121.426 87.859  133.468 1.00 209.21 ? 97  G   C "O2'" 1 
ATOM   7656 C "C1'" . G   C 2 97  ? 121.786 90.223  133.431 1.00 209.21 ? 97  G   C "C1'" 1 
ATOM   7657 N N9    . G   C 2 97  ? 121.624 91.388  134.329 1.00 209.21 ? 97  G   C N9    1 
ATOM   7658 C C8    . G   C 2 97  ? 120.711 92.411  134.224 1.00 209.21 ? 97  G   C C8    1 
ATOM   7659 N N7    . G   C 2 97  ? 120.821 93.307  135.167 1.00 209.21 ? 97  G   C N7    1 
ATOM   7660 C C5    . G   C 2 97  ? 121.867 92.853  135.957 1.00 209.21 ? 97  G   C C5    1 
ATOM   7661 C C6    . G   C 2 97  ? 122.445 93.406  137.136 1.00 209.21 ? 97  G   C C6    1 
ATOM   7662 O O6    . G   C 2 97  ? 122.156 94.440  137.751 1.00 209.21 ? 97  G   C O6    1 
ATOM   7663 N N1    . G   C 2 97  ? 123.486 92.620  137.610 1.00 209.21 ? 97  G   C N1    1 
ATOM   7664 C C2    . G   C 2 97  ? 123.906 91.449  137.034 1.00 209.21 ? 97  G   C C2    1 
ATOM   7665 N N2    . G   C 2 97  ? 124.933 90.872  137.664 1.00 209.21 ? 97  G   C N2    1 
ATOM   7666 N N3    . G   C 2 97  ? 123.388 90.922  135.936 1.00 209.21 ? 97  G   C N3    1 
ATOM   7667 C C4    . G   C 2 97  ? 122.372 91.669  135.453 1.00 209.21 ? 97  G   C C4    1 
ATOM   7668 P P     . C   C 2 98  ? 117.718 87.766  133.296 1.00 223.58 ? 98  C   C P     1 
ATOM   7669 O OP1   . C   C 2 98  ? 117.085 86.575  132.675 1.00 223.58 ? 98  C   C OP1   1 
ATOM   7670 O OP2   . C   C 2 98  ? 116.893 88.964  133.597 1.00 223.58 ? 98  C   C OP2   1 
ATOM   7671 O "O5'" . C   C 2 98  ? 118.426 87.303  134.646 1.00 223.58 ? 98  C   C "O5'" 1 
ATOM   7672 C "C5'" . C   C 2 98  ? 118.148 87.968  135.868 1.00 223.58 ? 98  C   C "C5'" 1 
ATOM   7673 C "C4'" . C   C 2 98  ? 119.162 87.645  136.936 1.00 223.58 ? 98  C   C "C4'" 1 
ATOM   7674 O "O4'" . C   C 2 98  ? 120.222 88.645  136.909 1.00 223.58 ? 98  C   C "O4'" 1 
ATOM   7675 C "C3'" . C   C 2 98  ? 118.641 87.699  138.367 1.00 223.58 ? 98  C   C "C3'" 1 
ATOM   7676 O "O3'" . C   C 2 98  ? 117.965 86.519  138.774 1.00 223.58 ? 98  C   C "O3'" 1 
ATOM   7677 C "C2'" . C   C 2 98  ? 119.904 88.001  139.161 1.00 223.58 ? 98  C   C "C2'" 1 
ATOM   7678 O "O2'" . C   C 2 98  ? 120.719 86.843  139.268 1.00 223.58 ? 98  C   C "O2'" 1 
ATOM   7679 C "C1'" . C   C 2 98  ? 120.595 88.992  138.228 1.00 223.58 ? 98  C   C "C1'" 1 
ATOM   7680 N N1    . C   C 2 98  ? 120.110 90.368  138.482 1.00 223.58 ? 98  C   C N1    1 
ATOM   7681 C C2    . C   C 2 98  ? 120.418 91.038  139.676 1.00 223.58 ? 98  C   C C2    1 
ATOM   7682 O O2    . C   C 2 98  ? 121.121 90.519  140.558 1.00 223.58 ? 98  C   C O2    1 
ATOM   7683 N N3    . C   C 2 98  ? 119.923 92.278  139.871 1.00 223.58 ? 98  C   C N3    1 
ATOM   7684 C C4    . C   C 2 98  ? 119.173 92.857  138.934 1.00 223.58 ? 98  C   C C4    1 
ATOM   7685 N N4    . C   C 2 98  ? 118.711 94.076  139.203 1.00 223.58 ? 98  C   C N4    1 
ATOM   7686 C C5    . C   C 2 98  ? 118.833 92.204  137.719 1.00 223.58 ? 98  C   C C5    1 
ATOM   7687 C C6    . C   C 2 98  ? 119.321 90.976  137.543 1.00 223.58 ? 98  C   C C6    1 
ATOM   7688 P P     . U   C 2 99  ? 116.373 86.371  138.564 1.00 232.52 ? 99  U   C P     1 
ATOM   7689 O OP1   . U   C 2 99  ? 116.105 84.973  138.146 1.00 232.52 ? 99  U   C OP1   1 
ATOM   7690 O OP2   . U   C 2 99  ? 115.867 87.495  137.741 1.00 232.52 ? 99  U   C OP2   1 
ATOM   7691 O "O5'" . U   C 2 99  ? 115.745 86.586  140.012 1.00 232.52 ? 99  U   C "O5'" 1 
ATOM   7692 C "C5'" . U   C 2 99  ? 114.333 86.652  140.171 1.00 232.52 ? 99  U   C "C5'" 1 
ATOM   7693 C "C4'" . U   C 2 99  ? 113.930 87.554  141.312 1.00 232.52 ? 99  U   C "C4'" 1 
ATOM   7694 O "O4'" . U   C 2 99  ? 115.021 88.450  141.646 1.00 232.52 ? 99  U   C "O4'" 1 
ATOM   7695 C "C3'" . U   C 2 99  ? 112.760 88.488  141.041 1.00 232.52 ? 99  U   C "C3'" 1 
ATOM   7696 O "O3'" . U   C 2 99  ? 111.497 87.859  141.160 1.00 232.52 ? 99  U   C "O3'" 1 
ATOM   7697 C "C2'" . U   C 2 99  ? 112.984 89.601  142.056 1.00 232.52 ? 99  U   C "C2'" 1 
ATOM   7698 O "O2'" . U   C 2 99  ? 112.555 89.195  143.347 1.00 232.52 ? 99  U   C "O2'" 1 
ATOM   7699 C "C1'" . U   C 2 99  ? 114.507 89.698  142.066 1.00 232.52 ? 99  U   C "C1'" 1 
ATOM   7700 N N1    . U   C 2 99  ? 115.012 90.749  141.156 1.00 232.52 ? 99  U   C N1    1 
ATOM   7701 C C2    . U   C 2 99  ? 115.069 92.046  141.632 1.00 232.52 ? 99  U   C C2    1 
ATOM   7702 O O2    . U   C 2 99  ? 114.714 92.355  142.757 1.00 232.52 ? 99  U   C O2    1 
ATOM   7703 N N3    . U   C 2 99  ? 115.559 92.968  140.741 1.00 232.52 ? 99  U   C N3    1 
ATOM   7704 C C4    . U   C 2 99  ? 115.984 92.720  139.452 1.00 232.52 ? 99  U   C C4    1 
ATOM   7705 O O4    . U   C 2 99  ? 116.401 93.644  138.754 1.00 232.52 ? 99  U   C O4    1 
ATOM   7706 C C5    . U   C 2 99  ? 115.895 91.355  139.038 1.00 232.52 ? 99  U   C C5    1 
ATOM   7707 C C6    . U   C 2 99  ? 115.426 90.438  139.884 1.00 232.52 ? 99  U   C C6    1 
ATOM   7708 P P     . U   C 2 100 ? 110.224 88.457  140.380 1.00 238.28 ? 100 U   C P     1 
ATOM   7709 O OP1   . U   C 2 100 ? 109.092 87.513  140.554 1.00 238.28 ? 100 U   C OP1   1 
ATOM   7710 O OP2   . U   C 2 100 ? 110.663 88.834  139.012 1.00 238.28 ? 100 U   C OP2   1 
ATOM   7711 O "O5'" . U   C 2 100 ? 109.878 89.798  141.168 1.00 238.28 ? 100 U   C "O5'" 1 
ATOM   7712 C "C5'" . U   C 2 100 ? 109.497 89.764  142.536 1.00 238.28 ? 100 U   C "C5'" 1 
ATOM   7713 C "C4'" . U   C 2 100 ? 109.476 91.145  143.143 1.00 238.28 ? 100 U   C "C4'" 1 
ATOM   7714 O "O4'" . U   C 2 100 ? 110.799 91.741  143.082 1.00 238.28 ? 100 U   C "O4'" 1 
ATOM   7715 C "C3'" . U   C 2 100 ? 108.585 92.162  142.451 1.00 238.28 ? 100 U   C "C3'" 1 
ATOM   7716 O "O3'" . U   C 2 100 ? 107.221 92.024  142.803 1.00 238.28 ? 100 U   C "O3'" 1 
ATOM   7717 C "C2'" . U   C 2 100 ? 109.200 93.489  142.880 1.00 238.28 ? 100 U   C "C2'" 1 
ATOM   7718 O "O2'" . U   C 2 100 ? 108.796 93.827  144.198 1.00 238.28 ? 100 U   C "O2'" 1 
ATOM   7719 C "C1'" . U   C 2 100 ? 110.690 93.139  142.907 1.00 238.28 ? 100 U   C "C1'" 1 
ATOM   7720 N N1    . U   C 2 100 ? 111.378 93.520  141.651 1.00 238.28 ? 100 U   C N1    1 
ATOM   7721 C C2    . U   C 2 100 ? 111.779 94.836  141.496 1.00 238.28 ? 100 U   C C2    1 
ATOM   7722 O O2    . U   C 2 100 ? 111.588 95.688  142.347 1.00 238.28 ? 100 U   C O2    1 
ATOM   7723 N N3    . U   C 2 100 ? 112.414 95.120  140.308 1.00 238.28 ? 100 U   C N3    1 
ATOM   7724 C C4    . U   C 2 100 ? 112.678 94.230  139.284 1.00 238.28 ? 100 U   C C4    1 
ATOM   7725 O O4    . U   C 2 100 ? 113.258 94.607  138.266 1.00 238.28 ? 100 U   C O4    1 
ATOM   7726 C C5    . U   C 2 100 ? 112.235 92.894  139.525 1.00 238.28 ? 100 U   C C5    1 
ATOM   7727 C C6    . U   C 2 100 ? 111.616 92.592  140.668 1.00 238.28 ? 100 U   C C6    1 
ATOM   7728 P P     . G   C 2 101 ? 106.075 92.271  141.705 1.00 238.35 ? 101 G   C P     1 
ATOM   7729 O OP1   . G   C 2 101 ? 104.780 91.841  142.292 1.00 238.35 ? 101 G   C OP1   1 
ATOM   7730 O OP2   . G   C 2 101 ? 106.525 91.681  140.420 1.00 238.35 ? 101 G   C OP2   1 
ATOM   7731 O "O5'" . G   C 2 101 ? 106.039 93.855  141.550 1.00 238.35 ? 101 G   C "O5'" 1 
ATOM   7732 C "C5'" . G   C 2 101 ? 105.787 94.677  142.679 1.00 238.35 ? 101 G   C "C5'" 1 
ATOM   7733 C "C4'" . G   C 2 101 ? 105.846 96.143  142.338 1.00 238.35 ? 101 G   C "C4'" 1 
ATOM   7734 O "O4'" . G   C 2 101 ? 107.224 96.567  142.146 1.00 238.35 ? 101 G   C "O4'" 1 
ATOM   7735 C "C3'" . G   C 2 101 ? 105.169 96.572  141.050 1.00 238.35 ? 101 G   C "C3'" 1 
ATOM   7736 O "O3'" . G   C 2 101 ? 103.755 96.603  141.116 1.00 238.35 ? 101 G   C "O3'" 1 
ATOM   7737 C "C2'" . G   C 2 101 ? 105.822 97.921  140.793 1.00 238.35 ? 101 G   C "C2'" 1 
ATOM   7738 O "O2'" . G   C 2 101 ? 105.310 98.904  141.680 1.00 238.35 ? 101 G   C "O2'" 1 
ATOM   7739 C "C1'" . G   C 2 101 ? 107.267 97.614  141.193 1.00 238.35 ? 101 G   C "C1'" 1 
ATOM   7740 N N9    . G   C 2 101 ? 108.032 97.167  140.015 1.00 238.35 ? 101 G   C N9    1 
ATOM   7741 C C8    . G   C 2 101 ? 108.115 95.895  139.501 1.00 238.35 ? 101 G   C C8    1 
ATOM   7742 N N7    . G   C 2 101 ? 108.842 95.829  138.420 1.00 238.35 ? 101 G   C N7    1 
ATOM   7743 C C5    . G   C 2 101 ? 109.247 97.136  138.197 1.00 238.35 ? 101 G   C C5    1 
ATOM   7744 C C6    . G   C 2 101 ? 110.055 97.682  137.170 1.00 238.35 ? 101 G   C C6    1 
ATOM   7745 O O6    . G   C 2 101 ? 110.590 97.097  136.222 1.00 238.35 ? 101 G   C O6    1 
ATOM   7746 N N1    . G   C 2 101 ? 110.216 99.055  137.323 1.00 238.35 ? 101 G   C N1    1 
ATOM   7747 C C2    . G   C 2 101 ? 109.672 99.811  138.333 1.00 238.35 ? 101 G   C C2    1 
ATOM   7748 N N2    . G   C 2 101 ? 109.937 101.125 138.319 1.00 238.35 ? 101 G   C N2    1 
ATOM   7749 N N3    . G   C 2 101 ? 108.917 99.310  139.296 1.00 238.35 ? 101 G   C N3    1 
ATOM   7750 C C4    . G   C 2 101 ? 108.746 97.977  139.166 1.00 238.35 ? 101 G   C C4    1 
ATOM   7751 P P     . C   C 2 102 ? 102.903 95.744  140.056 1.00 238.26 ? 102 C   C P     1 
ATOM   7752 O OP1   . C   C 2 102 ? 101.661 96.496  139.743 1.00 238.26 ? 102 C   C OP1   1 
ATOM   7753 O OP2   . C   C 2 102 ? 102.811 94.350  140.561 1.00 238.26 ? 102 C   C OP2   1 
ATOM   7754 O "O5'" . C   C 2 102 ? 103.822 95.736  138.752 1.00 238.26 ? 102 C   C "O5'" 1 
ATOM   7755 C "C5'" . C   C 2 102 ? 103.764 94.671  137.810 1.00 238.26 ? 102 C   C "C5'" 1 
ATOM   7756 C "C4'" . C   C 2 102 ? 104.539 95.005  136.557 1.00 238.26 ? 102 C   C "C4'" 1 
ATOM   7757 O "O4'" . C   C 2 102 ? 105.909 95.347  136.902 1.00 238.26 ? 102 C   C "O4'" 1 
ATOM   7758 C "C3'" . C   C 2 102 ? 104.696 93.890  135.534 1.00 238.26 ? 102 C   C "C3'" 1 
ATOM   7759 O "O3'" . C   C 2 102 ? 103.550 93.678  134.730 1.00 238.26 ? 102 C   C "O3'" 1 
ATOM   7760 C "C2'" . C   C 2 102 ? 105.921 94.341  134.751 1.00 238.26 ? 102 C   C "C2'" 1 
ATOM   7761 O "O2'" . C   C 2 102 ? 105.584 95.384  133.849 1.00 238.26 ? 102 C   C "O2'" 1 
ATOM   7762 C "C1'" . C   C 2 102 ? 106.781 94.929  135.869 1.00 238.26 ? 102 C   C "C1'" 1 
ATOM   7763 N N1    . C   C 2 102 ? 107.724 93.922  136.409 1.00 238.26 ? 102 C   C N1    1 
ATOM   7764 C C2    . C   C 2 102 ? 108.955 93.766  135.767 1.00 238.26 ? 102 C   C C2    1 
ATOM   7765 O O2    . C   C 2 102 ? 109.215 94.485  134.790 1.00 238.26 ? 102 C   C O2    1 
ATOM   7766 N N3    . C   C 2 102 ? 109.834 92.847  136.230 1.00 238.26 ? 102 C   C N3    1 
ATOM   7767 C C4    . C   C 2 102 ? 109.517 92.096  137.284 1.00 238.26 ? 102 C   C C4    1 
ATOM   7768 N N4    . C   C 2 102 ? 110.409 91.197  137.706 1.00 238.26 ? 102 C   C N4    1 
ATOM   7769 C C5    . C   C 2 102 ? 108.267 92.226  137.952 1.00 238.26 ? 102 C   C C5    1 
ATOM   7770 C C6    . C   C 2 102 ? 107.408 93.140  137.486 1.00 238.26 ? 102 C   C C6    1 
ATOM   7771 P P     . A   C 2 103 ? 103.243 92.216  134.130 1.00 231.25 ? 103 A   C P     1 
ATOM   7772 O OP1   . A   C 2 103 ? 102.919 92.374  132.690 1.00 231.25 ? 103 A   C OP1   1 
ATOM   7773 O OP2   . A   C 2 103 ? 102.271 91.546  135.031 1.00 231.25 ? 103 A   C OP2   1 
ATOM   7774 O "O5'" . A   C 2 103 ? 104.632 91.437  134.236 1.00 231.25 ? 103 A   C "O5'" 1 
ATOM   7775 C "C5'" . A   C 2 103 ? 104.810 90.377  135.167 1.00 231.25 ? 103 A   C "C5'" 1 
ATOM   7776 C "C4'" . A   C 2 103 ? 105.007 89.051  134.473 1.00 231.25 ? 103 A   C "C4'" 1 
ATOM   7777 O "O4'" . A   C 2 103 ? 104.003 88.894  133.438 1.00 231.25 ? 103 A   C "O4'" 1 
ATOM   7778 C "C3'" . A   C 2 103 ? 106.329 88.859  133.743 1.00 231.25 ? 103 A   C "C3'" 1 
ATOM   7779 O "O3'" . A   C 2 103 ? 107.381 88.459  134.605 1.00 231.25 ? 103 A   C "O3'" 1 
ATOM   7780 C "C2'" . A   C 2 103 ? 105.981 87.808  132.696 1.00 231.25 ? 103 A   C "C2'" 1 
ATOM   7781 O "O2'" . A   C 2 103 ? 105.967 86.511  133.272 1.00 231.25 ? 103 A   C "O2'" 1 
ATOM   7782 C "C1'" . A   C 2 103 ? 104.545 88.194  132.339 1.00 231.25 ? 103 A   C "C1'" 1 
ATOM   7783 N N9    . A   C 2 103 ? 104.485 89.065  131.152 1.00 231.25 ? 103 A   C N9    1 
ATOM   7784 C C8    . A   C 2 103 ? 105.508 89.395  130.298 1.00 231.25 ? 103 A   C C8    1 
ATOM   7785 N N7    . A   C 2 103 ? 105.144 90.190  129.321 1.00 231.25 ? 103 A   C N7    1 
ATOM   7786 C C5    . A   C 2 103 ? 103.789 90.392  129.544 1.00 231.25 ? 103 A   C C5    1 
ATOM   7787 C C6    . A   C 2 103 ? 102.817 91.141  128.857 1.00 231.25 ? 103 A   C C6    1 
ATOM   7788 N N6    . A   C 2 103 ? 103.072 91.857  127.759 1.00 231.25 ? 103 A   C N6    1 
ATOM   7789 N N1    . A   C 2 103 ? 101.556 91.131  129.343 1.00 231.25 ? 103 A   C N1    1 
ATOM   7790 C C2    . A   C 2 103 ? 101.299 90.414  130.444 1.00 231.25 ? 103 A   C C2    1 
ATOM   7791 N N3    . A   C 2 103 ? 102.126 89.671  131.176 1.00 231.25 ? 103 A   C N3    1 
ATOM   7792 C C4    . A   C 2 103 ? 103.369 89.701  130.665 1.00 231.25 ? 103 A   C C4    1 
ATOM   7793 P P     . U   C 2 104 ? 108.494 89.514  135.089 1.00 237.39 ? 104 U   C P     1 
ATOM   7794 O OP1   . U   C 2 104 ? 108.685 89.320  136.548 1.00 237.39 ? 104 U   C OP1   1 
ATOM   7795 O OP2   . U   C 2 104 ? 108.126 90.853  134.562 1.00 237.39 ? 104 U   C OP2   1 
ATOM   7796 O "O5'" . U   C 2 104 ? 109.829 89.041  134.357 1.00 237.39 ? 104 U   C "O5'" 1 
ATOM   7797 C "C5'" . U   C 2 104 ? 111.107 89.425  134.848 1.00 237.39 ? 104 U   C "C5'" 1 
ATOM   7798 C "C4'" . U   C 2 104 ? 112.185 89.221  133.811 1.00 237.39 ? 104 U   C "C4'" 1 
ATOM   7799 O "O4'" . U   C 2 104 ? 112.191 87.831  133.402 1.00 237.39 ? 104 U   C "O4'" 1 
ATOM   7800 C "C3'" . U   C 2 104 ? 112.020 90.001  132.511 1.00 237.39 ? 104 U   C "C3'" 1 
ATOM   7801 O "O3'" . U   C 2 104 ? 112.555 91.314  132.585 1.00 237.39 ? 104 U   C "O3'" 1 
ATOM   7802 C "C2'" . U   C 2 104 ? 112.747 89.132  131.488 1.00 237.39 ? 104 U   C "C2'" 1 
ATOM   7803 O "O2'" . U   C 2 104 ? 114.144 89.388  131.513 1.00 237.39 ? 104 U   C "O2'" 1 
ATOM   7804 C "C1'" . U   C 2 104 ? 112.505 87.723  132.033 1.00 237.39 ? 104 U   C "C1'" 1 
ATOM   7805 N N1    . U   C 2 104 ? 111.400 87.013  131.347 1.00 237.39 ? 104 U   C N1    1 
ATOM   7806 C C2    . U   C 2 104 ? 111.722 86.252  130.240 1.00 237.39 ? 104 U   C C2    1 
ATOM   7807 O O2    . U   C 2 104 ? 112.858 86.162  129.808 1.00 237.39 ? 104 U   C O2    1 
ATOM   7808 N N3    . U   C 2 104 ? 110.663 85.603  129.655 1.00 237.39 ? 104 U   C N3    1 
ATOM   7809 C C4    . U   C 2 104 ? 109.344 85.633  130.058 1.00 237.39 ? 104 U   C C4    1 
ATOM   7810 O O4    . U   C 2 104 ? 108.502 84.994  129.425 1.00 237.39 ? 104 U   C O4    1 
ATOM   7811 C C5    . U   C 2 104 ? 109.094 86.437  131.215 1.00 237.39 ? 104 U   C C5    1 
ATOM   7812 C C6    . U   C 2 104 ? 110.106 87.080  131.807 1.00 237.39 ? 104 U   C C6    1 
ATOM   7813 P P     . A   C 2 105 ? 111.882 92.438  133.517 1.00 245.57 ? 105 A   C P     1 
ATOM   7814 O OP1   . A   C 2 105 ? 112.543 92.390  134.847 1.00 245.57 ? 105 A   C OP1   1 
ATOM   7815 O OP2   . A   C 2 105 ? 110.410 92.278  133.426 1.00 245.57 ? 105 A   C OP2   1 
ATOM   7816 O "O5'" . A   C 2 105 ? 112.288 93.814  132.822 1.00 245.57 ? 105 A   C "O5'" 1 
ATOM   7817 C "C5'" . A   C 2 105 ? 113.629 94.067  132.427 1.00 245.57 ? 105 A   C "C5'" 1 
ATOM   7818 C "C4'" . A   C 2 105 ? 113.766 94.087  130.925 1.00 245.57 ? 105 A   C "C4'" 1 
ATOM   7819 O "O4'" . A   C 2 105 ? 113.156 92.895  130.370 1.00 245.57 ? 105 A   C "O4'" 1 
ATOM   7820 C "C3'" . A   C 2 105 ? 113.071 95.232  130.201 1.00 245.57 ? 105 A   C "C3'" 1 
ATOM   7821 O "O3'" . A   C 2 105 ? 113.834 96.428  130.200 1.00 245.57 ? 105 A   C "O3'" 1 
ATOM   7822 C "C2'" . A   C 2 105 ? 112.841 94.663  128.804 1.00 245.57 ? 105 A   C "C2'" 1 
ATOM   7823 O "O2'" . A   C 2 105 ? 114.015 94.780  128.015 1.00 245.57 ? 105 A   C "O2'" 1 
ATOM   7824 C "C1'" . A   C 2 105 ? 112.605 93.179  129.103 1.00 245.57 ? 105 A   C "C1'" 1 
ATOM   7825 N N9    . A   C 2 105 ? 111.175 92.800  129.087 1.00 245.57 ? 105 A   C N9    1 
ATOM   7826 C C8    . A   C 2 105 ? 110.593 91.933  128.195 1.00 245.57 ? 105 A   C C8    1 
ATOM   7827 N N7    . A   C 2 105 ? 109.309 91.752  128.377 1.00 245.57 ? 105 A   C N7    1 
ATOM   7828 C C5    . A   C 2 105 ? 109.016 92.556  129.467 1.00 245.57 ? 105 A   C C5    1 
ATOM   7829 C C6    . A   C 2 105 ? 107.814 92.803  130.155 1.00 245.57 ? 105 A   C C6    1 
ATOM   7830 N N6    . A   C 2 105 ? 106.648 92.244  129.829 1.00 245.57 ? 105 A   C N6    1 
ATOM   7831 N N1    . A   C 2 105 ? 107.847 93.655  131.201 1.00 245.57 ? 105 A   C N1    1 
ATOM   7832 C C2    . A   C 2 105 ? 109.018 94.214  131.525 1.00 245.57 ? 105 A   C C2    1 
ATOM   7833 N N3    . A   C 2 105 ? 110.211 94.061  130.955 1.00 245.57 ? 105 A   C N3    1 
ATOM   7834 C C4    . A   C 2 105 ? 110.152 93.210  129.917 1.00 245.57 ? 105 A   C C4    1 
ATOM   7835 P P     . G   C 2 106 ? 113.495 97.613  131.233 1.00 235.69 ? 106 G   C P     1 
ATOM   7836 O OP1   . G   C 2 106 ? 114.771 98.071  131.838 1.00 235.69 ? 106 G   C OP1   1 
ATOM   7837 O OP2   . G   C 2 106 ? 112.391 97.152  132.111 1.00 235.69 ? 106 G   C OP2   1 
ATOM   7838 O "O5'" . G   C 2 106 ? 112.936 98.792  130.315 1.00 235.69 ? 106 G   C "O5'" 1 
ATOM   7839 C "C5'" . G   C 2 106 ? 113.752 99.406  129.326 1.00 235.69 ? 106 G   C "C5'" 1 
ATOM   7840 C "C4'" . G   C 2 106 ? 113.157 100.709 128.848 1.00 235.69 ? 106 G   C "C4'" 1 
ATOM   7841 O "O4'" . G   C 2 106 ? 111.708 100.607 128.852 1.00 235.69 ? 106 G   C "O4'" 1 
ATOM   7842 C "C3'" . G   C 2 106 ? 113.445 101.935 129.704 1.00 235.69 ? 106 G   C "C3'" 1 
ATOM   7843 O "O3'" . G   C 2 106 ? 114.709 102.519 129.431 1.00 235.69 ? 106 G   C "O3'" 1 
ATOM   7844 C "C2'" . G   C 2 106 ? 112.271 102.850 129.379 1.00 235.69 ? 106 G   C "C2'" 1 
ATOM   7845 O "O2'" . G   C 2 106 ? 112.463 103.485 128.123 1.00 235.69 ? 106 G   C "O2'" 1 
ATOM   7846 C "C1'" . G   C 2 106 ? 111.134 101.838 129.239 1.00 235.69 ? 106 G   C "C1'" 1 
ATOM   7847 N N9    . G   C 2 106 ? 110.430 101.642 130.522 1.00 235.69 ? 106 G   C N9    1 
ATOM   7848 C C8    . G   C 2 106 ? 110.233 102.591 131.495 1.00 235.69 ? 106 G   C C8    1 
ATOM   7849 N N7    . G   C 2 106 ? 109.577 102.142 132.529 1.00 235.69 ? 106 G   C N7    1 
ATOM   7850 C C5    . G   C 2 106 ? 109.317 100.814 132.220 1.00 235.69 ? 106 G   C C5    1 
ATOM   7851 C C6    . G   C 2 106 ? 108.634 99.816  132.963 1.00 235.69 ? 106 G   C C6    1 
ATOM   7852 O O6    . G   C 2 106 ? 108.105 99.911  134.077 1.00 235.69 ? 106 G   C O6    1 
ATOM   7853 N N1    . G   C 2 106 ? 108.597 98.605  132.280 1.00 235.69 ? 106 G   C N1    1 
ATOM   7854 C C2    . G   C 2 106 ? 109.148 98.383  131.042 1.00 235.69 ? 106 G   C C2    1 
ATOM   7855 N N2    . G   C 2 106 ? 109.012 97.149  130.541 1.00 235.69 ? 106 G   C N2    1 
ATOM   7856 N N3    . G   C 2 106 ? 109.785 99.303  130.341 1.00 235.69 ? 106 G   C N3    1 
ATOM   7857 C C4    . G   C 2 106 ? 109.832 100.490 130.982 1.00 235.69 ? 106 G   C C4    1 
ATOM   7858 P P     . C   C 2 107 ? 115.917 102.392 130.485 1.00 233.68 ? 107 C   C P     1 
ATOM   7859 O OP1   . C   C 2 107 ? 117.028 103.254 130.007 1.00 233.68 ? 107 C   C OP1   1 
ATOM   7860 O OP2   . C   C 2 107 ? 116.167 100.951 130.739 1.00 233.68 ? 107 C   C OP2   1 
ATOM   7861 O "O5'" . C   C 2 107 ? 115.344 103.034 131.826 1.00 233.68 ? 107 C   C "O5'" 1 
ATOM   7862 C "C5'" . C   C 2 107 ? 115.332 104.441 132.025 1.00 233.68 ? 107 C   C "C5'" 1 
ATOM   7863 C "C4'" . C   C 2 107 ? 114.628 104.805 133.308 1.00 233.68 ? 107 C   C "C4'" 1 
ATOM   7864 O "O4'" . C   C 2 107 ? 113.248 104.356 133.244 1.00 233.68 ? 107 C   C "O4'" 1 
ATOM   7865 C "C3'" . C   C 2 107 ? 115.177 104.154 134.571 1.00 233.68 ? 107 C   C "C3'" 1 
ATOM   7866 O "O3'" . C   C 2 107 ? 116.291 104.845 135.111 1.00 233.68 ? 107 C   C "O3'" 1 
ATOM   7867 C "C2'" . C   C 2 107 ? 113.967 104.136 135.494 1.00 233.68 ? 107 C   C "C2'" 1 
ATOM   7868 O "O2'" . C   C 2 107 ? 113.761 105.415 136.076 1.00 233.68 ? 107 C   C "O2'" 1 
ATOM   7869 C "C1'" . C   C 2 107 ? 112.835 103.870 134.504 1.00 233.68 ? 107 C   C "C1'" 1 
ATOM   7870 N N1    . C   C 2 107 ? 112.534 102.426 134.363 1.00 233.68 ? 107 C   C N1    1 
ATOM   7871 C C2    . C   C 2 107 ? 111.884 101.725 135.386 1.00 233.68 ? 107 C   C C2    1 
ATOM   7872 O O2    . C   C 2 107 ? 111.570 102.320 136.427 1.00 233.68 ? 107 C   C O2    1 
ATOM   7873 N N3    . C   C 2 107 ? 111.623 100.406 135.210 1.00 233.68 ? 107 C   C N3    1 
ATOM   7874 C C4    . C   C 2 107 ? 111.973 99.792  134.079 1.00 233.68 ? 107 C   C C4    1 
ATOM   7875 N N4    . C   C 2 107 ? 111.698 98.493  133.943 1.00 233.68 ? 107 C   C N4    1 
ATOM   7876 C C5    . C   C 2 107 ? 112.627 100.483 133.024 1.00 233.68 ? 107 C   C C5    1 
ATOM   7877 C C6    . C   C 2 107 ? 112.881 101.781 133.210 1.00 233.68 ? 107 C   C C6    1 
ATOM   7878 P P     . A   C 2 108 ? 117.358 104.072 136.033 1.00 234.74 ? 108 A   C P     1 
ATOM   7879 O OP1   . A   C 2 108 ? 118.519 104.973 136.247 1.00 234.74 ? 108 A   C OP1   1 
ATOM   7880 O OP2   . A   C 2 108 ? 117.576 102.724 135.448 1.00 234.74 ? 108 A   C OP2   1 
ATOM   7881 O "O5'" . A   C 2 108 ? 116.611 103.888 137.429 1.00 234.74 ? 108 A   C "O5'" 1 
ATOM   7882 C "C5'" . A   C 2 108 ? 116.280 105.008 138.239 1.00 234.74 ? 108 A   C "C5'" 1 
ATOM   7883 C "C4'" . A   C 2 108 ? 115.412 104.607 139.406 1.00 234.74 ? 108 A   C "C4'" 1 
ATOM   7884 O "O4'" . A   C 2 108 ? 114.186 104.003 138.917 1.00 234.74 ? 108 A   C "O4'" 1 
ATOM   7885 C "C3'" . A   C 2 108 ? 115.999 103.560 140.342 1.00 234.74 ? 108 A   C "C3'" 1 
ATOM   7886 O "O3'" . A   C 2 108 ? 116.874 104.121 141.307 1.00 234.74 ? 108 A   C "O3'" 1 
ATOM   7887 C "C2'" . A   C 2 108 ? 114.759 102.914 140.949 1.00 234.74 ? 108 A   C "C2'" 1 
ATOM   7888 O "O2'" . A   C 2 108 ? 114.231 103.722 141.991 1.00 234.74 ? 108 A   C "O2'" 1 
ATOM   7889 C "C1'" . A   C 2 108 ? 113.787 102.951 139.770 1.00 234.74 ? 108 A   C "C1'" 1 
ATOM   7890 N N9    . A   C 2 108 ? 113.795 101.699 138.990 1.00 234.74 ? 108 A   C N9    1 
ATOM   7891 C C8    . A   C 2 108 ? 114.288 101.536 137.720 1.00 234.74 ? 108 A   C C8    1 
ATOM   7892 N N7    . A   C 2 108 ? 114.162 100.321 137.250 1.00 234.74 ? 108 A   C N7    1 
ATOM   7893 C C5    . A   C 2 108 ? 113.539 99.634  138.281 1.00 234.74 ? 108 A   C C5    1 
ATOM   7894 C C6    . A   C 2 108 ? 113.132 98.296  138.398 1.00 234.74 ? 108 A   C C6    1 
ATOM   7895 N N6    . A   C 2 108 ? 113.303 97.398  137.428 1.00 234.74 ? 108 A   C N6    1 
ATOM   7896 N N1    . A   C 2 108 ? 112.539 97.911  139.550 1.00 234.74 ? 108 A   C N1    1 
ATOM   7897 C C2    . A   C 2 108 ? 112.374 98.828  140.514 1.00 234.74 ? 108 A   C C2    1 
ATOM   7898 N N3    . A   C 2 108 ? 112.715 100.118 140.521 1.00 234.74 ? 108 A   C N3    1 
ATOM   7899 C C4    . A   C 2 108 ? 113.302 100.466 139.361 1.00 234.74 ? 108 A   C C4    1 
ATOM   7900 P P     . A   C 2 109 ? 118.237 103.370 141.709 1.00 236.75 ? 109 A   C P     1 
ATOM   7901 O OP1   . A   C 2 109 ? 119.187 104.387 142.227 1.00 236.75 ? 109 A   C OP1   1 
ATOM   7902 O OP2   . A   C 2 109 ? 118.638 102.505 140.570 1.00 236.75 ? 109 A   C OP2   1 
ATOM   7903 O "O5'" . A   C 2 109 ? 117.819 102.424 142.921 1.00 236.75 ? 109 A   C "O5'" 1 
ATOM   7904 C "C5'" . A   C 2 109 ? 117.288 102.962 144.125 1.00 236.75 ? 109 A   C "C5'" 1 
ATOM   7905 C "C4'" . A   C 2 109 ? 116.494 101.927 144.881 1.00 236.75 ? 109 A   C "C4'" 1 
ATOM   7906 O "O4'" . A   C 2 109 ? 115.410 101.446 144.043 1.00 236.75 ? 109 A   C "O4'" 1 
ATOM   7907 C "C3'" . A   C 2 109 ? 117.255 100.668 145.275 1.00 236.75 ? 109 A   C "C3'" 1 
ATOM   7908 O "O3'" . A   C 2 109 ? 117.987 100.822 146.479 1.00 236.75 ? 109 A   C "O3'" 1 
ATOM   7909 C "C2'" . A   C 2 109 ? 116.154 99.620  145.360 1.00 236.75 ? 109 A   C "C2'" 1 
ATOM   7910 O "O2'" . A   C 2 109 ? 115.442 99.740  146.583 1.00 236.75 ? 109 A   C "O2'" 1 
ATOM   7911 C "C1'" . A   C 2 109 ? 115.235 100.058 144.222 1.00 236.75 ? 109 A   C "C1'" 1 
ATOM   7912 N N9    . A   C 2 109 ? 115.573 99.394  142.950 1.00 236.75 ? 109 A   C N9    1 
ATOM   7913 C C8    . A   C 2 109 ? 116.190 99.970  141.869 1.00 236.75 ? 109 A   C C8    1 
ATOM   7914 N N7    . A   C 2 109 ? 116.370 99.156  140.861 1.00 236.75 ? 109 A   C N7    1 
ATOM   7915 C C5    . A   C 2 109 ? 115.835 97.959  141.311 1.00 236.75 ? 109 A   C C5    1 
ATOM   7916 C C6    . A   C 2 109 ? 115.721 96.701  140.703 1.00 236.75 ? 109 A   C C6    1 
ATOM   7917 N N6    . A   C 2 109 ? 116.159 96.449  139.470 1.00 236.75 ? 109 A   C N6    1 
ATOM   7918 N N1    . A   C 2 109 ? 115.138 95.708  141.409 1.00 236.75 ? 109 A   C N1    1 
ATOM   7919 C C2    . A   C 2 109 ? 114.705 95.977  142.648 1.00 236.75 ? 109 A   C C2    1 
ATOM   7920 N N3    . A   C 2 109 ? 114.753 97.122  143.329 1.00 236.75 ? 109 A   C N3    1 
ATOM   7921 C C4    . A   C 2 109 ? 115.338 98.086  142.596 1.00 236.75 ? 109 A   C C4    1 
ATOM   7922 P P     . G   C 2 110 ? 119.410 100.099 146.666 1.00 232.33 ? 110 G   C P     1 
ATOM   7923 O OP1   . G   C 2 110 ? 120.233 100.934 147.578 1.00 232.33 ? 110 G   C OP1   1 
ATOM   7924 O OP2   . G   C 2 110 ? 119.930 99.753  145.318 1.00 232.33 ? 110 G   C OP2   1 
ATOM   7925 O "O5'" . G   C 2 110 ? 119.062 98.740  147.423 1.00 232.33 ? 110 G   C "O5'" 1 
ATOM   7926 C "C5'" . G   C 2 110 ? 119.746 98.371  148.612 1.00 232.33 ? 110 G   C "C5'" 1 
ATOM   7927 C "C4'" . G   C 2 110 ? 120.543 97.104  148.422 1.00 232.33 ? 110 G   C "C4'" 1 
ATOM   7928 O "O4'" . G   C 2 110 ? 119.653 96.017  148.062 1.00 232.33 ? 110 G   C "O4'" 1 
ATOM   7929 C "C3'" . G   C 2 110 ? 121.575 97.133  147.305 1.00 232.33 ? 110 G   C "C3'" 1 
ATOM   7930 O "O3'" . G   C 2 110 ? 122.796 97.729  147.710 1.00 232.33 ? 110 G   C "O3'" 1 
ATOM   7931 C "C2'" . G   C 2 110 ? 121.711 95.664  146.928 1.00 232.33 ? 110 G   C "C2'" 1 
ATOM   7932 O "O2'" . G   C 2 110 ? 122.561 94.988  147.843 1.00 232.33 ? 110 G   C "O2'" 1 
ATOM   7933 C "C1'" . G   C 2 110 ? 120.283 95.160  147.134 1.00 232.33 ? 110 G   C "C1'" 1 
ATOM   7934 N N9    . G   C 2 110 ? 119.488 95.166  145.891 1.00 232.33 ? 110 G   C N9    1 
ATOM   7935 C C8    . G   C 2 110 ? 118.506 96.075  145.579 1.00 232.33 ? 110 G   C C8    1 
ATOM   7936 N N7    . G   C 2 110 ? 117.941 95.849  144.428 1.00 232.33 ? 110 G   C N7    1 
ATOM   7937 C C5    . G   C 2 110 ? 118.587 94.720  143.951 1.00 232.33 ? 110 G   C C5    1 
ATOM   7938 C C6    . G   C 2 110 ? 118.392 94.003  142.746 1.00 232.33 ? 110 G   C C6    1 
ATOM   7939 O O6    . G   C 2 110 ? 117.619 94.232  141.814 1.00 232.33 ? 110 G   C O6    1 
ATOM   7940 N N1    . G   C 2 110 ? 119.257 92.921  142.639 1.00 232.33 ? 110 G   C N1    1 
ATOM   7941 C C2    . G   C 2 110 ? 120.179 92.551  143.583 1.00 232.33 ? 110 G   C C2    1 
ATOM   7942 N N2    . G   C 2 110 ? 120.909 91.465  143.275 1.00 232.33 ? 110 G   C N2    1 
ATOM   7943 N N3    . G   C 2 110 ? 120.372 93.209  144.720 1.00 232.33 ? 110 G   C N3    1 
ATOM   7944 C C4    . G   C 2 110 ? 119.546 94.276  144.840 1.00 232.33 ? 110 G   C C4    1 
ATOM   7945 P P     . U   C 2 111 ? 123.814 98.325  146.619 1.00 218.29 ? 111 U   C P     1 
ATOM   7946 O OP1   . U   C 2 111 ? 124.711 99.287  147.309 1.00 218.29 ? 111 U   C OP1   1 
ATOM   7947 O OP2   . U   C 2 111 ? 123.021 98.773  145.445 1.00 218.29 ? 111 U   C OP2   1 
ATOM   7948 O "O5'" . U   C 2 111 ? 124.688 97.069  146.176 1.00 218.29 ? 111 U   C "O5'" 1 
ATOM   7949 C "C5'" . U   C 2 111 ? 125.554 96.416  147.094 1.00 218.29 ? 111 U   C "C5'" 1 
ATOM   7950 C "C4'" . U   C 2 111 ? 126.199 95.204  146.470 1.00 218.29 ? 111 U   C "C4'" 1 
ATOM   7951 O "O4'" . U   C 2 111 ? 125.173 94.253  146.096 1.00 218.29 ? 111 U   C "O4'" 1 
ATOM   7952 C "C3'" . U   C 2 111 ? 126.972 95.458  145.184 1.00 218.29 ? 111 U   C "C3'" 1 
ATOM   7953 O "O3'" . U   C 2 111 ? 128.301 95.883  145.436 1.00 218.29 ? 111 U   C "O3'" 1 
ATOM   7954 C "C2'" . U   C 2 111 ? 126.896 94.119  144.459 1.00 218.29 ? 111 U   C "C2'" 1 
ATOM   7955 O "O2'" . U   C 2 111 ? 127.890 93.228  144.943 1.00 218.29 ? 111 U   C "O2'" 1 
ATOM   7956 C "C1'" . U   C 2 111 ? 125.529 93.596  144.900 1.00 218.29 ? 111 U   C "C1'" 1 
ATOM   7957 N N1    . U   C 2 111 ? 124.449 93.810  143.909 1.00 218.29 ? 111 U   C N1    1 
ATOM   7958 C C2    . U   C 2 111 ? 124.341 92.933  142.846 1.00 218.29 ? 111 U   C C2    1 
ATOM   7959 O O2    . U   C 2 111 ? 125.120 92.014  142.661 1.00 218.29 ? 111 U   C O2    1 
ATOM   7960 N N3    . U   C 2 111 ? 123.290 93.182  141.996 1.00 218.29 ? 111 U   C N3    1 
ATOM   7961 C C4    . U   C 2 111 ? 122.354 94.190  142.103 1.00 218.29 ? 111 U   C C4    1 
ATOM   7962 O O4    . U   C 2 111 ? 121.462 94.286  141.259 1.00 218.29 ? 111 U   C O4    1 
ATOM   7963 C C5    . U   C 2 111 ? 122.523 95.043  143.238 1.00 218.29 ? 111 U   C C5    1 
ATOM   7964 C C6    . U   C 2 111 ? 123.536 94.823  144.081 1.00 218.29 ? 111 U   C C6    1 
ATOM   7965 P P     . C   C 2 112 ? 129.097 96.771  144.360 1.00 200.18 ? 112 C   C P     1 
ATOM   7966 O OP1   . C   C 2 112 ? 130.373 97.208  144.980 1.00 200.18 ? 112 C   C OP1   1 
ATOM   7967 O OP2   . C   C 2 112 ? 128.157 97.785  143.818 1.00 200.18 ? 112 C   C OP2   1 
ATOM   7968 O "O5'" . C   C 2 112 ? 129.441 95.747  143.188 1.00 200.18 ? 112 C   C "O5'" 1 
ATOM   7969 C "C5'" . C   C 2 112 ? 130.326 94.653  143.392 1.00 200.18 ? 112 C   C "C5'" 1 
ATOM   7970 C "C4'" . C   C 2 112 ? 130.430 93.814  142.145 1.00 200.18 ? 112 C   C "C4'" 1 
ATOM   7971 O "O4'" . C   C 2 112 ? 129.165 93.148  141.906 1.00 200.18 ? 112 C   C "O4'" 1 
ATOM   7972 C "C3'" . C   C 2 112 ? 130.699 94.595  140.868 1.00 200.18 ? 112 C   C "C3'" 1 
ATOM   7973 O "O3'" . C   C 2 112 ? 132.081 94.821  140.662 1.00 200.18 ? 112 C   C "O3'" 1 
ATOM   7974 C "C2'" . C   C 2 112 ? 130.062 93.731  139.785 1.00 200.18 ? 112 C   C "C2'" 1 
ATOM   7975 O "O2'" . C   C 2 112 ? 130.936 92.678  139.406 1.00 200.18 ? 112 C   C "O2'" 1 
ATOM   7976 C "C1'" . C   C 2 112 ? 128.873 93.127  140.526 1.00 200.18 ? 112 C   C "C1'" 1 
ATOM   7977 N N1    . C   C 2 112 ? 127.597 93.853  140.321 1.00 200.18 ? 112 C   C N1    1 
ATOM   7978 C C2    . C   C 2 112 ? 126.678 93.404  139.369 1.00 200.18 ? 112 C   C C2    1 
ATOM   7979 O O2    . C   C 2 112 ? 126.933 92.493  138.579 1.00 200.18 ? 112 C   C O2    1 
ATOM   7980 N N3    . C   C 2 112 ? 125.515 94.063  139.180 1.00 200.18 ? 112 C   C N3    1 
ATOM   7981 C C4    . C   C 2 112 ? 125.198 95.076  139.985 1.00 200.18 ? 112 C   C C4    1 
ATOM   7982 N N4    . C   C 2 112 ? 124.035 95.682  139.760 1.00 200.18 ? 112 C   C N4    1 
ATOM   7983 C C5    . C   C 2 112 ? 126.089 95.551  140.988 1.00 200.18 ? 112 C   C C5    1 
ATOM   7984 C C6    . C   C 2 112 ? 127.255 94.906  141.124 1.00 200.18 ? 112 C   C C6    1 
ATOM   7985 P P     . U   C 2 113 ? 132.710 96.285  140.855 1.00 185.32 ? 113 U   C P     1 
ATOM   7986 O OP1   . U   C 2 113 ? 133.535 96.273  142.090 1.00 185.32 ? 113 U   C OP1   1 
ATOM   7987 O OP2   . U   C 2 113 ? 131.625 97.289  140.711 1.00 185.32 ? 113 U   C OP2   1 
ATOM   7988 O "O5'" . U   C 2 113 ? 133.692 96.422  139.611 1.00 185.32 ? 113 U   C "O5'" 1 
ATOM   7989 C "C5'" . U   C 2 113 ? 134.395 95.289  139.123 1.00 185.32 ? 113 U   C "C5'" 1 
ATOM   7990 C "C4'" . U   C 2 113 ? 133.934 94.908  137.739 1.00 185.32 ? 113 U   C "C4'" 1 
ATOM   7991 O "O4'" . U   C 2 113 ? 132.609 94.324  137.804 1.00 185.32 ? 113 U   C "O4'" 1 
ATOM   7992 C "C3'" . U   C 2 113 ? 133.781 96.052  136.751 1.00 185.32 ? 113 U   C "C3'" 1 
ATOM   7993 O "O3'" . U   C 2 113 ? 135.014 96.460  136.185 1.00 185.32 ? 113 U   C "O3'" 1 
ATOM   7994 C "C2'" . U   C 2 113 ? 132.788 95.491  135.739 1.00 185.32 ? 113 U   C "C2'" 1 
ATOM   7995 O "O2'" . U   C 2 113 ? 133.442 94.629  134.819 1.00 185.32 ? 113 U   C "O2'" 1 
ATOM   7996 C "C1'" . U   C 2 113 ? 131.882 94.643  136.635 1.00 185.32 ? 113 U   C "C1'" 1 
ATOM   7997 N N1    . U   C 2 113 ? 130.634 95.346  137.022 1.00 185.32 ? 113 U   C N1    1 
ATOM   7998 C C2    . U   C 2 113 ? 129.458 94.877  136.471 1.00 185.32 ? 113 U   C C2    1 
ATOM   7999 O O2    . U   C 2 113 ? 129.423 93.932  135.703 1.00 185.32 ? 113 U   C O2    1 
ATOM   8000 N N3    . U   C 2 113 ? 128.323 95.547  136.857 1.00 185.32 ? 113 U   C N3    1 
ATOM   8001 C C4    . U   C 2 113 ? 128.242 96.620  137.718 1.00 185.32 ? 113 U   C C4    1 
ATOM   8002 O O4    . U   C 2 113 ? 127.143 97.120  137.966 1.00 185.32 ? 113 U   C O4    1 
ATOM   8003 C C5    . U   C 2 113 ? 129.500 97.049  138.248 1.00 185.32 ? 113 U   C C5    1 
ATOM   8004 C C6    . U   C 2 113 ? 130.621 96.419  137.884 1.00 185.32 ? 113 U   C C6    1 
ATOM   8005 P P     . U   C 2 114 ? 135.240 97.998  135.780 1.00 160.00 ? 114 U   C P     1 
ATOM   8006 O OP1   . U   C 2 114 ? 133.959 98.719  135.991 1.00 160.00 ? 114 U   C OP1   1 
ATOM   8007 O OP2   . U   C 2 114 ? 135.889 98.020  134.446 1.00 160.00 ? 114 U   C OP2   1 
ATOM   8008 O "O5'" . U   C 2 114 ? 136.299 98.540  136.842 1.00 160.00 ? 114 U   C "O5'" 1 
ATOM   8009 C "C5'" . U   C 2 114 ? 136.427 97.940  138.121 1.00 160.00 ? 114 U   C "C5'" 1 
ATOM   8010 C "C4'" . U   C 2 114 ? 136.015 98.879  139.228 1.00 160.00 ? 114 U   C "C4'" 1 
ATOM   8011 O "O4'" . U   C 2 114 ? 137.146 99.683  139.644 1.00 160.00 ? 114 U   C "O4'" 1 
ATOM   8012 C "C3'" . U   C 2 114 ? 134.947 99.904  138.890 1.00 160.00 ? 114 U   C "C3'" 1 
ATOM   8013 O "O3'" . U   C 2 114 ? 133.636 99.368  138.888 1.00 160.00 ? 114 U   C "O3'" 1 
ATOM   8014 C "C2'" . U   C 2 114 ? 135.171 100.973 139.954 1.00 160.00 ? 114 U   C "C2'" 1 
ATOM   8015 O "O2'" . U   C 2 114 ? 134.588 100.582 141.188 1.00 160.00 ? 114 U   C "O2'" 1 
ATOM   8016 C "C1'" . U   C 2 114 ? 136.695 100.941 140.105 1.00 160.00 ? 114 U   C "C1'" 1 
ATOM   8017 N N1    . U   C 2 114 ? 137.360 102.010 139.324 1.00 160.00 ? 114 U   C N1    1 
ATOM   8018 C C2    . U   C 2 114 ? 138.700 102.228 139.572 1.00 160.00 ? 114 U   C C2    1 
ATOM   8019 O O2    . U   C 2 114 ? 139.338 101.556 140.362 1.00 160.00 ? 114 U   C O2    1 
ATOM   8020 N N3    . U   C 2 114 ? 139.271 103.236 138.836 1.00 160.00 ? 114 U   C N3    1 
ATOM   8021 C C4    . U   C 2 114 ? 138.642 104.048 137.914 1.00 160.00 ? 114 U   C C4    1 
ATOM   8022 O O4    . U   C 2 114 ? 139.288 104.920 137.332 1.00 160.00 ? 114 U   C O4    1 
ATOM   8023 C C5    . U   C 2 114 ? 137.251 103.776 137.730 1.00 160.00 ? 114 U   C C5    1 
ATOM   8024 C C6    . U   C 2 114 ? 136.672 102.796 138.429 1.00 160.00 ? 114 U   C C6    1 
ATOM   8025 P P     . A   C 2 115 ? 132.403 100.262 138.377 1.00 155.52 ? 115 A   C P     1 
ATOM   8026 O OP1   . A   C 2 115 ? 131.928 101.091 139.514 1.00 155.52 ? 115 A   C OP1   1 
ATOM   8027 O OP2   . A   C 2 115 ? 131.450 99.374  137.668 1.00 155.52 ? 115 A   C OP2   1 
ATOM   8028 O "O5'" . A   C 2 115 ? 133.046 101.231 137.289 1.00 155.52 ? 115 A   C "O5'" 1 
ATOM   8029 C "C5'" . A   C 2 115 ? 132.269 102.254 136.683 1.00 155.52 ? 115 A   C "C5'" 1 
ATOM   8030 C "C4'" . A   C 2 115 ? 132.785 102.613 135.312 1.00 155.52 ? 115 A   C "C4'" 1 
ATOM   8031 O "O4'" . A   C 2 115 ? 134.075 103.266 135.421 1.00 155.52 ? 115 A   C "O4'" 1 
ATOM   8032 C "C3'" . A   C 2 115 ? 133.036 101.452 134.363 1.00 155.52 ? 115 A   C "C3'" 1 
ATOM   8033 O "O3'" . A   C 2 115 ? 131.850 101.002 133.732 1.00 155.52 ? 115 A   C "O3'" 1 
ATOM   8034 C "C2'" . A   C 2 115 ? 134.057 102.028 133.388 1.00 155.52 ? 115 A   C "C2'" 1 
ATOM   8035 O "O2'" . A   C 2 115 ? 133.416 102.823 132.404 1.00 155.52 ? 115 A   C "O2'" 1 
ATOM   8036 C "C1'" . A   C 2 115 ? 134.869 102.954 134.297 1.00 155.52 ? 115 A   C "C1'" 1 
ATOM   8037 N N9    . A   C 2 115 ? 136.129 102.341 134.756 1.00 155.52 ? 115 A   C N9    1 
ATOM   8038 C C8    . A   C 2 115 ? 136.298 101.192 135.483 1.00 155.52 ? 115 A   C C8    1 
ATOM   8039 N N7    . A   C 2 115 ? 137.550 100.912 135.747 1.00 155.52 ? 115 A   C N7    1 
ATOM   8040 C C5    . A   C 2 115 ? 138.253 101.949 135.155 1.00 155.52 ? 115 A   C C5    1 
ATOM   8041 C C6    . A   C 2 115 ? 139.625 102.236 135.076 1.00 155.52 ? 115 A   C C6    1 
ATOM   8042 N N6    . A   C 2 115 ? 140.571 101.466 135.619 1.00 155.52 ? 115 A   C N6    1 
ATOM   8043 N N1    . A   C 2 115 ? 139.997 103.354 134.414 1.00 155.52 ? 115 A   C N1    1 
ATOM   8044 C C2    . A   C 2 115 ? 139.045 104.123 133.872 1.00 155.52 ? 115 A   C C2    1 
ATOM   8045 N N3    . A   C 2 115 ? 137.725 103.957 133.880 1.00 155.52 ? 115 A   C N3    1 
ATOM   8046 C C4    . A   C 2 115 ? 137.391 102.840 134.546 1.00 155.52 ? 115 A   C C4    1 
ATOM   8047 P P     . G   C 2 116 ? 131.571 99.431  133.543 1.00 156.61 ? 116 G   C P     1 
ATOM   8048 O OP1   . G   C 2 116 ? 130.551 99.276  132.476 1.00 156.61 ? 116 G   C OP1   1 
ATOM   8049 O OP2   . G   C 2 116 ? 131.328 98.836  134.881 1.00 156.61 ? 116 G   C OP2   1 
ATOM   8050 O "O5'" . G   C 2 116 ? 132.947 98.855  132.987 1.00 156.61 ? 116 G   C "O5'" 1 
ATOM   8051 C "C5'" . G   C 2 116 ? 132.966 97.700  132.156 1.00 156.61 ? 116 G   C "C5'" 1 
ATOM   8052 C "C4'" . G   C 2 116 ? 134.366 97.341  131.723 1.00 156.61 ? 116 G   C "C4'" 1 
ATOM   8053 O "O4'" . G   C 2 116 ? 134.289 96.419  130.602 1.00 156.61 ? 116 G   C "O4'" 1 
ATOM   8054 C "C3'" . G   C 2 116 ? 135.220 98.514  131.248 1.00 156.61 ? 116 G   C "C3'" 1 
ATOM   8055 O "O3'" . G   C 2 116 ? 136.588 98.254  131.559 1.00 156.61 ? 116 G   C "O3'" 1 
ATOM   8056 C "C2'" . G   C 2 116 ? 135.025 98.477  129.737 1.00 156.61 ? 116 G   C "C2'" 1 
ATOM   8057 O "O2'" . G   C 2 116 ? 136.069 99.075  128.998 1.00 156.61 ? 116 G   C "O2'" 1 
ATOM   8058 C "C1'" . G   C 2 116 ? 134.938 96.976  129.474 1.00 156.61 ? 116 G   C "C1'" 1 
ATOM   8059 N N9    . G   C 2 116 ? 134.158 96.627  128.285 1.00 156.61 ? 116 G   C N9    1 
ATOM   8060 C C8    . G   C 2 116 ? 134.631 96.128  127.095 1.00 156.61 ? 116 G   C C8    1 
ATOM   8061 N N7    . G   C 2 116 ? 133.687 95.922  126.217 1.00 156.61 ? 116 G   C N7    1 
ATOM   8062 C C5    . G   C 2 116 ? 132.522 96.311  126.863 1.00 156.61 ? 116 G   C C5    1 
ATOM   8063 C C6    . G   C 2 116 ? 131.175 96.316  126.414 1.00 156.61 ? 116 G   C C6    1 
ATOM   8064 O O6    . G   C 2 116 ? 130.727 95.964  125.316 1.00 156.61 ? 116 G   C O6    1 
ATOM   8065 N N1    . G   C 2 116 ? 130.309 96.791  127.394 1.00 156.61 ? 116 G   C N1    1 
ATOM   8066 C C2    . G   C 2 116 ? 130.687 97.207  128.647 1.00 156.61 ? 116 G   C C2    1 
ATOM   8067 N N2    . G   C 2 116 ? 129.704 97.634  129.453 1.00 156.61 ? 116 G   C N2    1 
ATOM   8068 N N3    . G   C 2 116 ? 131.937 97.209  129.076 1.00 156.61 ? 116 G   C N3    1 
ATOM   8069 C C4    . G   C 2 116 ? 132.796 96.753  128.140 1.00 156.61 ? 116 G   C C4    1 
ATOM   8070 P P     . A   C 2 117 ? 137.615 99.468  131.792 1.00 138.31 ? 117 A   C P     1 
ATOM   8071 O OP1   . A   C 2 117 ? 138.750 99.286  130.851 1.00 138.31 ? 117 A   C OP1   1 
ATOM   8072 O OP2   . A   C 2 117 ? 137.885 99.582  133.245 1.00 138.31 ? 117 A   C OP2   1 
ATOM   8073 O "O5'" . A   C 2 117 ? 136.807 100.760 131.332 1.00 138.31 ? 117 A   C "O5'" 1 
ATOM   8074 C "C5'" . A   C 2 117 ? 137.394 101.695 130.433 1.00 138.31 ? 117 A   C "C5'" 1 
ATOM   8075 C "C4'" . A   C 2 117 ? 136.381 102.272 129.476 1.00 138.31 ? 117 A   C "C4'" 1 
ATOM   8076 O "O4'" . A   C 2 117 ? 135.626 103.315 130.154 1.00 138.31 ? 117 A   C "O4'" 1 
ATOM   8077 C "C3'" . A   C 2 117 ? 136.976 102.922 128.230 1.00 138.31 ? 117 A   C "C3'" 1 
ATOM   8078 O "O3'" . A   C 2 117 ? 136.072 102.762 127.137 1.00 138.31 ? 117 A   C "O3'" 1 
ATOM   8079 C "C2'" . A   C 2 117 ? 137.044 104.393 128.624 1.00 138.31 ? 117 A   C "C2'" 1 
ATOM   8080 O "O2'" . A   C 2 117 ? 137.062 105.293 127.536 1.00 138.31 ? 117 A   C "O2'" 1 
ATOM   8081 C "C1'" . A   C 2 117 ? 135.777 104.540 129.460 1.00 138.31 ? 117 A   C "C1'" 1 
ATOM   8082 N N9    . A   C 2 117 ? 135.828 105.626 130.442 1.00 138.31 ? 117 A   C N9    1 
ATOM   8083 C C8    . A   C 2 117 ? 136.109 105.541 131.782 1.00 138.31 ? 117 A   C C8    1 
ATOM   8084 N N7    . A   C 2 117 ? 136.066 106.692 132.406 1.00 138.31 ? 117 A   C N7    1 
ATOM   8085 C C5    . A   C 2 117 ? 135.725 107.596 131.410 1.00 138.31 ? 117 A   C C5    1 
ATOM   8086 C C6    . A   C 2 117 ? 135.519 108.986 131.422 1.00 138.31 ? 117 A   C C6    1 
ATOM   8087 N N6    . A   C 2 117 ? 135.631 109.743 132.515 1.00 138.31 ? 117 A   C N6    1 
ATOM   8088 N N1    . A   C 2 117 ? 135.189 109.580 130.255 1.00 138.31 ? 117 A   C N1    1 
ATOM   8089 C C2    . A   C 2 117 ? 135.076 108.823 129.156 1.00 138.31 ? 117 A   C C2    1 
ATOM   8090 N N3    . A   C 2 117 ? 135.244 107.511 129.019 1.00 138.31 ? 117 A   C N3    1 
ATOM   8091 C C4    . A   C 2 117 ? 135.566 106.951 130.197 1.00 138.31 ? 117 A   C C4    1 
ATOM   8092 P P     . A   C 2 118 ? 136.457 101.806 125.905 1.00 136.52 ? 118 A   C P     1 
ATOM   8093 O OP1   . A   C 2 118 ? 137.410 100.781 126.403 1.00 136.52 ? 118 A   C OP1   1 
ATOM   8094 O OP2   . A   C 2 118 ? 136.835 102.669 124.758 1.00 136.52 ? 118 A   C OP2   1 
ATOM   8095 O "O5'" . A   C 2 118 ? 135.091 101.070 125.545 1.00 136.52 ? 118 A   C "O5'" 1 
ATOM   8096 C "C5'" . A   C 2 118 ? 134.555 100.073 126.401 1.00 136.52 ? 118 A   C "C5'" 1 
ATOM   8097 C "C4'" . A   C 2 118 ? 133.053 100.005 126.301 1.00 136.52 ? 118 A   C "C4'" 1 
ATOM   8098 O "O4'" . A   C 2 118 ? 132.491 99.765  127.617 1.00 136.52 ? 118 A   C "O4'" 1 
ATOM   8099 C "C3'" . A   C 2 118 ? 132.366 101.276 125.828 1.00 136.52 ? 118 A   C "C3'" 1 
ATOM   8100 O "O3'" . A   C 2 118 ? 132.365 101.399 124.416 1.00 136.52 ? 118 A   C "O3'" 1 
ATOM   8101 C "C2'" . A   C 2 118 ? 130.973 101.149 126.428 1.00 136.52 ? 118 A   C "C2'" 1 
ATOM   8102 O "O2'" . A   C 2 118 ? 130.173 100.266 125.655 1.00 136.52 ? 118 A   C "O2'" 1 
ATOM   8103 C "C1'" . A   C 2 118 ? 131.280 100.474 127.763 1.00 136.52 ? 118 A   C "C1'" 1 
ATOM   8104 N N9    . A   C 2 118 ? 131.447 101.449 128.856 1.00 136.52 ? 118 A   C N9    1 
ATOM   8105 C C8    . A   C 2 118 ? 132.629 101.882 129.402 1.00 136.52 ? 118 A   C C8    1 
ATOM   8106 N N7    . A   C 2 118 ? 132.476 102.752 130.368 1.00 136.52 ? 118 A   C N7    1 
ATOM   8107 C C5    . A   C 2 118 ? 131.101 102.898 130.469 1.00 136.52 ? 118 A   C C5    1 
ATOM   8108 C C6    . A   C 2 118 ? 130.301 103.684 131.312 1.00 136.52 ? 118 A   C C6    1 
ATOM   8109 N N6    . A   C 2 118 ? 130.798 104.496 132.247 1.00 136.52 ? 118 A   C N6    1 
ATOM   8110 N N1    . A   C 2 118 ? 128.962 103.604 131.158 1.00 136.52 ? 118 A   C N1    1 
ATOM   8111 C C2    . A   C 2 118 ? 128.474 102.785 130.217 1.00 136.52 ? 118 A   C C2    1 
ATOM   8112 N N3    . A   C 2 118 ? 129.125 101.997 129.364 1.00 136.52 ? 118 A   C N3    1 
ATOM   8113 C C4    . A   C 2 118 ? 130.452 102.101 129.544 1.00 136.52 ? 118 A   C C4    1 
ATOM   8114 P P     . U   C 2 119 ? 132.449 102.848 123.729 1.00 115.98 ? 119 U   C P     1 
ATOM   8115 O OP1   . U   C 2 119 ? 132.728 102.654 122.283 1.00 115.98 ? 119 U   C OP1   1 
ATOM   8116 O OP2   . U   C 2 119 ? 133.353 103.694 124.547 1.00 115.98 ? 119 U   C OP2   1 
ATOM   8117 O "O5'" . U   C 2 119 ? 130.972 103.425 123.871 1.00 115.98 ? 119 U   C "O5'" 1 
ATOM   8118 C "C5'" . U   C 2 119 ? 129.853 102.690 123.398 1.00 115.98 ? 119 U   C "C5'" 1 
ATOM   8119 C "C4'" . U   C 2 119 ? 128.562 103.266 123.920 1.00 115.98 ? 119 U   C "C4'" 1 
ATOM   8120 O "O4'" . U   C 2 119 ? 128.533 103.170 125.368 1.00 115.98 ? 119 U   C "O4'" 1 
ATOM   8121 C "C3'" . U   C 2 119 ? 128.344 104.744 123.642 1.00 115.98 ? 119 U   C "C3'" 1 
ATOM   8122 O "O3'" . U   C 2 119 ? 127.849 104.985 122.337 1.00 115.98 ? 119 U   C "O3'" 1 
ATOM   8123 C "C2'" . U   C 2 119 ? 127.384 105.157 124.751 1.00 115.98 ? 119 U   C "C2'" 1 
ATOM   8124 O "O2'" . U   C 2 119 ? 126.055 104.771 124.433 1.00 115.98 ? 119 U   C "O2'" 1 
ATOM   8125 C "C1'" . U   C 2 119 ? 127.873 104.292 125.914 1.00 115.98 ? 119 U   C "C1'" 1 
ATOM   8126 N N1    . U   C 2 119 ? 128.821 105.012 126.795 1.00 115.98 ? 119 U   C N1    1 
ATOM   8127 C C2    . U   C 2 119 ? 128.305 105.867 127.752 1.00 115.98 ? 119 U   C C2    1 
ATOM   8128 O O2    . U   C 2 119 ? 127.108 106.054 127.891 1.00 115.98 ? 119 U   C O2    1 
ATOM   8129 N N3    . U   C 2 119 ? 129.241 106.498 128.537 1.00 115.98 ? 119 U   C N3    1 
ATOM   8130 C C4    . U   C 2 119 ? 130.613 106.353 128.457 1.00 115.98 ? 119 U   C C4    1 
ATOM   8131 O O4    . U   C 2 119 ? 131.348 106.975 129.223 1.00 115.98 ? 119 U   C O4    1 
ATOM   8132 C C5    . U   C 2 119 ? 131.065 105.449 127.446 1.00 115.98 ? 119 U   C C5    1 
ATOM   8133 C C6    . U   C 2 119 ? 130.177 104.825 126.672 1.00 115.98 ? 119 U   C C6    1 
ATOM   8134 P P     . G   C 2 120 ? 128.712 105.850 121.295 1.00 97.29  ? 120 G   C P     1 
ATOM   8135 O OP1   . G   C 2 120 ? 128.538 105.257 119.945 1.00 97.29  ? 120 G   C OP1   1 
ATOM   8136 O OP2   . G   C 2 120 ? 130.078 106.014 121.854 1.00 97.29  ? 120 G   C OP2   1 
ATOM   8137 O "O5'" . G   C 2 120 ? 127.999 107.273 121.305 1.00 97.29  ? 120 G   C "O5'" 1 
ATOM   8138 C "C5'" . G   C 2 120 ? 128.759 108.470 121.306 1.00 97.29  ? 120 G   C "C5'" 1 
ATOM   8139 C "C4'" . G   C 2 120 ? 128.069 109.552 122.097 1.00 97.29  ? 120 G   C "C4'" 1 
ATOM   8140 O "O4'" . G   C 2 120 ? 127.815 109.084 123.447 1.00 97.29  ? 120 G   C "O4'" 1 
ATOM   8141 C "C3'" . G   C 2 120 ? 128.854 110.838 122.293 1.00 97.29  ? 120 G   C "C3'" 1 
ATOM   8142 O "O3'" . G   C 2 120 ? 128.779 111.702 121.173 1.00 97.29  ? 120 G   C "O3'" 1 
ATOM   8143 C "C2'" . G   C 2 120 ? 128.229 111.420 123.554 1.00 97.29  ? 120 G   C "C2'" 1 
ATOM   8144 O "O2'" . G   C 2 120 ? 126.995 112.056 123.255 1.00 97.29  ? 120 G   C "O2'" 1 
ATOM   8145 C "C1'" . G   C 2 120 ? 127.936 110.155 124.359 1.00 97.29  ? 120 G   C "C1'" 1 
ATOM   8146 N N9    . G   C 2 120 ? 129.009 109.835 125.321 1.00 97.29  ? 120 G   C N9    1 
ATOM   8147 C C8    . G   C 2 120 ? 129.973 108.867 125.181 1.00 97.29  ? 120 G   C C8    1 
ATOM   8148 N N7    . G   C 2 120 ? 130.786 108.801 126.199 1.00 97.29  ? 120 G   C N7    1 
ATOM   8149 C C5    . G   C 2 120 ? 130.329 109.781 127.068 1.00 97.29  ? 120 G   C C5    1 
ATOM   8150 C C6    . G   C 2 120 ? 130.814 110.176 128.340 1.00 97.29  ? 120 G   C C6    1 
ATOM   8151 O O6    . G   C 2 120 ? 131.775 109.720 128.970 1.00 97.29  ? 120 G   C O6    1 
ATOM   8152 N N1    . G   C 2 120 ? 130.059 111.209 128.882 1.00 97.29  ? 120 G   C N1    1 
ATOM   8153 C C2    . G   C 2 120 ? 128.974 111.791 128.275 1.00 97.29  ? 120 G   C C2    1 
ATOM   8154 N N2    . G   C 2 120 ? 128.362 112.777 128.945 1.00 97.29  ? 120 G   C N2    1 
ATOM   8155 N N3    . G   C 2 120 ? 128.512 111.431 127.087 1.00 97.29  ? 120 G   C N3    1 
ATOM   8156 C C4    . G   C 2 120 ? 129.231 110.427 126.543 1.00 97.29  ? 120 G   C C4    1 
ATOM   8157 P P     . C   C 2 121 ? 130.008 112.673 120.816 1.00 82.62  ? 121 C   C P     1 
ATOM   8158 O OP1   . C   C 2 121 ? 129.746 113.276 119.485 1.00 82.62  ? 121 C   C OP1   1 
ATOM   8159 O OP2   . C   C 2 121 ? 131.268 111.921 121.046 1.00 82.62  ? 121 C   C OP2   1 
ATOM   8160 O "O5'" . C   C 2 121 ? 129.916 113.828 121.908 1.00 82.62  ? 121 C   C "O5'" 1 
ATOM   8161 C "C5'" . C   C 2 121 ? 128.745 114.622 122.035 1.00 82.62  ? 121 C   C "C5'" 1 
ATOM   8162 C "C4'" . C   C 2 121 ? 128.724 115.362 123.347 1.00 82.62  ? 121 C   C "C4'" 1 
ATOM   8163 O "O4'" . C   C 2 121 ? 128.679 114.414 124.446 1.00 82.62  ? 121 C   C "O4'" 1 
ATOM   8164 C "C3'" . C   C 2 121 ? 129.947 116.213 123.645 1.00 82.62  ? 121 C   C "C3'" 1 
ATOM   8165 O "O3'" . C   C 2 121 ? 129.916 117.472 122.998 1.00 82.62  ? 121 C   C "O3'" 1 
ATOM   8166 C "C2'" . C   C 2 121 ? 129.929 116.298 125.165 1.00 82.62  ? 121 C   C "C2'" 1 
ATOM   8167 O "O2'" . C   C 2 121 ? 128.965 117.245 125.602 1.00 82.62  ? 121 C   C "O2'" 1 
ATOM   8168 C "C1'" . C   C 2 121 ? 129.434 114.901 125.536 1.00 82.62  ? 121 C   C "C1'" 1 
ATOM   8169 N N1    . C   C 2 121 ? 130.549 113.958 125.794 1.00 82.62  ? 121 C   C N1    1 
ATOM   8170 C C2    . C   C 2 121 ? 131.205 113.980 127.029 1.00 82.62  ? 121 C   C C2    1 
ATOM   8171 O O2    . C   C 2 121 ? 130.848 114.792 127.892 1.00 82.62  ? 121 C   C O2    1 
ATOM   8172 N N3    . C   C 2 121 ? 132.218 113.114 127.257 1.00 82.62  ? 121 C   C N3    1 
ATOM   8173 C C4    . C   C 2 121 ? 132.586 112.249 126.314 1.00 82.62  ? 121 C   C C4    1 
ATOM   8174 N N4    . C   C 2 121 ? 133.591 111.414 126.584 1.00 82.62  ? 121 C   C N4    1 
ATOM   8175 C C5    . C   C 2 121 ? 131.938 112.199 125.050 1.00 82.62  ? 121 C   C C5    1 
ATOM   8176 C C6    . C   C 2 121 ? 130.939 113.062 124.839 1.00 82.62  ? 121 C   C C6    1 
ATOM   8177 P P     . G   C 2 122 ? 131.109 117.897 122.011 1.00 75.39  ? 122 G   C P     1 
ATOM   8178 O OP1   . G   C 2 122 ? 130.580 118.903 121.057 1.00 75.39  ? 122 G   C OP1   1 
ATOM   8179 O OP2   . G   C 2 122 ? 131.738 116.656 121.493 1.00 75.39  ? 122 G   C OP2   1 
ATOM   8180 O "O5'" . G   C 2 122 ? 132.157 118.622 122.967 1.00 75.39  ? 122 G   C "O5'" 1 
ATOM   8181 C "C5'" . G   C 2 122 ? 131.794 119.793 123.683 1.00 75.39  ? 122 G   C "C5'" 1 
ATOM   8182 C "C4'" . G   C 2 122 ? 132.431 119.829 125.048 1.00 75.39  ? 122 G   C "C4'" 1 
ATOM   8183 O "O4'" . G   C 2 122 ? 132.123 118.609 125.766 1.00 75.39  ? 122 G   C "O4'" 1 
ATOM   8184 C "C3'" . G   C 2 122 ? 133.948 119.903 125.077 1.00 75.39  ? 122 G   C "C3'" 1 
ATOM   8185 O "O3'" . G   C 2 122 ? 134.431 121.222 124.891 1.00 75.39  ? 122 G   C "O3'" 1 
ATOM   8186 C "C2'" . G   C 2 122 ? 134.286 119.326 126.445 1.00 75.39  ? 122 G   C "C2'" 1 
ATOM   8187 O "O2'" . G   C 2 122 ? 134.106 120.303 127.458 1.00 75.39  ? 122 G   C "O2'" 1 
ATOM   8188 C "C1'" . G   C 2 122 ? 133.201 118.261 126.608 1.00 75.39  ? 122 G   C "C1'" 1 
ATOM   8189 N N9    . G   C 2 122 ? 133.670 116.909 126.250 1.00 75.39  ? 122 G   C N9    1 
ATOM   8190 C C8    . G   C 2 122 ? 133.261 116.139 125.190 1.00 75.39  ? 122 G   C C8    1 
ATOM   8191 N N7    . G   C 2 122 ? 133.847 114.976 125.140 1.00 75.39  ? 122 G   C N7    1 
ATOM   8192 C C5    . G   C 2 122 ? 134.695 114.977 126.236 1.00 75.39  ? 122 G   C C5    1 
ATOM   8193 C C6    . G   C 2 122 ? 135.592 113.986 126.698 1.00 75.39  ? 122 G   C C6    1 
ATOM   8194 O O6    . G   C 2 122 ? 135.819 112.871 126.216 1.00 75.39  ? 122 G   C O6    1 
ATOM   8195 N N1    . G   C 2 122 ? 136.258 114.396 127.847 1.00 75.39  ? 122 G   C N1    1 
ATOM   8196 C C2    . G   C 2 122 ? 136.083 115.604 128.472 1.00 75.39  ? 122 G   C C2    1 
ATOM   8197 N N2    . G   C 2 122 ? 136.821 115.816 129.571 1.00 75.39  ? 122 G   C N2    1 
ATOM   8198 N N3    . G   C 2 122 ? 135.253 116.540 128.048 1.00 75.39  ? 122 G   C N3    1 
ATOM   8199 C C4    . G   C 2 122 ? 134.596 116.160 126.934 1.00 75.39  ? 122 G   C C4    1 
ATOM   8200 P P     . G   C 2 123 ? 135.890 121.473 124.269 1.00 74.05  ? 123 G   C P     1 
ATOM   8201 O OP1   . G   C 2 123 ? 136.026 122.924 123.988 1.00 74.05  ? 123 G   C OP1   1 
ATOM   8202 O OP2   . G   C 2 123 ? 136.094 120.491 123.175 1.00 74.05  ? 123 G   C OP2   1 
ATOM   8203 O "O5'" . G   C 2 123 ? 136.887 121.106 125.456 1.00 74.05  ? 123 G   C "O5'" 1 
ATOM   8204 C "C5'" . G   C 2 123 ? 136.875 121.832 126.677 1.00 74.05  ? 123 G   C "C5'" 1 
ATOM   8205 C "C4'" . G   C 2 123 ? 137.816 121.218 127.683 1.00 74.05  ? 123 G   C "C4'" 1 
ATOM   8206 O "O4'" . G   C 2 123 ? 137.387 119.872 127.989 1.00 74.05  ? 123 G   C "O4'" 1 
ATOM   8207 C "C3'" . G   C 2 123 ? 139.257 121.068 127.222 1.00 74.05  ? 123 G   C "C3'" 1 
ATOM   8208 O "O3'" . G   C 2 123 ? 140.000 122.252 127.448 1.00 74.05  ? 123 G   C "O3'" 1 
ATOM   8209 C "C2'" . G   C 2 123 ? 139.769 119.881 128.035 1.00 74.05  ? 123 G   C "C2'" 1 
ATOM   8210 O "O2'" . G   C 2 123 ? 140.227 120.308 129.309 1.00 74.05  ? 123 G   C "O2'" 1 
ATOM   8211 C "C1'" . G   C 2 123 ? 138.503 119.047 128.232 1.00 74.05  ? 123 G   C "C1'" 1 
ATOM   8212 N N9    . G   C 2 123 ? 138.402 117.852 127.367 1.00 74.05  ? 123 G   C N9    1 
ATOM   8213 C C8    . G   C 2 123 ? 137.566 117.722 126.286 1.00 74.05  ? 123 G   C C8    1 
ATOM   8214 N N7    . G   C 2 123 ? 137.628 116.551 125.719 1.00 74.05  ? 123 G   C N7    1 
ATOM   8215 C C5    . G   C 2 123 ? 138.550 115.853 126.479 1.00 74.05  ? 123 G   C C5    1 
ATOM   8216 C C6    . G   C 2 123 ? 139.018 114.522 126.337 1.00 74.05  ? 123 G   C C6    1 
ATOM   8217 O O6    . G   C 2 123 ? 138.699 113.688 125.481 1.00 74.05  ? 123 G   C O6    1 
ATOM   8218 N N1    . G   C 2 123 ? 139.949 114.194 127.315 1.00 74.05  ? 123 G   C N1    1 
ATOM   8219 C C2    . G   C 2 123 ? 140.368 115.047 128.307 1.00 74.05  ? 123 G   C C2    1 
ATOM   8220 N N2    . G   C 2 123 ? 141.272 114.544 129.161 1.00 74.05  ? 123 G   C N2    1 
ATOM   8221 N N3    . G   C 2 123 ? 139.935 116.292 128.454 1.00 74.05  ? 123 G   C N3    1 
ATOM   8222 C C4    . G   C 2 123 ? 139.031 116.632 127.511 1.00 74.05  ? 123 G   C C4    1 
ATOM   8223 P P     . G   C 2 124 ? 140.779 122.982 126.249 1.00 76.74  ? 124 G   C P     1 
ATOM   8224 O OP1   . G   C 2 124 ? 140.458 124.431 126.306 1.00 76.74  ? 124 G   C OP1   1 
ATOM   8225 O OP2   . G   C 2 124 ? 140.524 122.220 125.001 1.00 76.74  ? 124 G   C OP2   1 
ATOM   8226 O "O5'" . G   C 2 124 ? 142.313 122.811 126.638 1.00 76.74  ? 124 G   C "O5'" 1 
ATOM   8227 C "C5'" . G   C 2 124 ? 142.739 122.881 127.993 1.00 76.74  ? 124 G   C "C5'" 1 
ATOM   8228 C "C4'" . G   C 2 124 ? 143.766 121.819 128.286 1.00 76.74  ? 124 G   C "C4'" 1 
ATOM   8229 O "O4'" . G   C 2 124 ? 143.105 120.538 128.437 1.00 76.74  ? 124 G   C "O4'" 1 
ATOM   8230 C "C3'" . G   C 2 124 ? 144.788 121.598 127.182 1.00 76.74  ? 124 G   C "C3'" 1 
ATOM   8231 O "O3'" . G   C 2 124 ? 145.885 122.488 127.286 1.00 76.74  ? 124 G   C "O3'" 1 
ATOM   8232 C "C2'" . G   C 2 124 ? 145.172 120.135 127.348 1.00 76.74  ? 124 G   C "C2'" 1 
ATOM   8233 O "O2'" . G   C 2 124 ? 146.129 119.984 128.385 1.00 76.74  ? 124 G   C "O2'" 1 
ATOM   8234 C "C1'" . G   C 2 124 ? 143.859 119.520 127.820 1.00 76.74  ? 124 G   C "C1'" 1 
ATOM   8235 N N9    . G   C 2 124 ? 143.036 118.961 126.732 1.00 76.74  ? 124 G   C N9    1 
ATOM   8236 C C8    . G   C 2 124 ? 142.220 119.660 125.877 1.00 76.74  ? 124 G   C C8    1 
ATOM   8237 N N7    . G   C 2 124 ? 141.572 118.898 125.041 1.00 76.74  ? 124 G   C N7    1 
ATOM   8238 C C5    . G   C 2 124 ? 141.978 117.613 125.366 1.00 76.74  ? 124 G   C C5    1 
ATOM   8239 C C6    . G   C 2 124 ? 141.614 116.367 124.796 1.00 76.74  ? 124 G   C C6    1 
ATOM   8240 O O6    . G   C 2 124 ? 140.835 116.140 123.863 1.00 76.74  ? 124 G   C O6    1 
ATOM   8241 N N1    . G   C 2 124 ? 142.261 115.315 125.429 1.00 76.74  ? 124 G   C N1    1 
ATOM   8242 C C2    . G   C 2 124 ? 143.142 115.451 126.471 1.00 76.74  ? 124 G   C C2    1 
ATOM   8243 N N2    . G   C 2 124 ? 143.666 114.320 126.947 1.00 76.74  ? 124 G   C N2    1 
ATOM   8244 N N3    . G   C 2 124 ? 143.491 116.603 127.012 1.00 76.74  ? 124 G   C N3    1 
ATOM   8245 C C4    . G   C 2 124 ? 142.876 117.636 126.412 1.00 76.74  ? 124 G   C C4    1 
ATOM   8246 P P     . U   C 2 125 ? 146.761 122.854 125.992 1.00 78.33  ? 125 U   C P     1 
ATOM   8247 O OP1   . U   C 2 125 ? 147.572 124.055 126.317 1.00 78.33  ? 125 U   C OP1   1 
ATOM   8248 O OP2   . U   C 2 125 ? 145.857 122.873 124.814 1.00 78.33  ? 125 U   C OP2   1 
ATOM   8249 O "O5'" . U   C 2 125 ? 147.752 121.617 125.842 1.00 78.33  ? 125 U   C "O5'" 1 
ATOM   8250 C "C5'" . U   C 2 125 ? 148.615 121.244 126.905 1.00 78.33  ? 125 U   C "C5'" 1 
ATOM   8251 C "C4'" . U   C 2 125 ? 149.098 119.826 126.745 1.00 78.33  ? 125 U   C "C4'" 1 
ATOM   8252 O "O4'" . U   C 2 125 ? 147.984 118.906 126.868 1.00 78.33  ? 125 U   C "O4'" 1 
ATOM   8253 C "C3'" . U   C 2 125 ? 149.705 119.486 125.396 1.00 78.33  ? 125 U   C "C3'" 1 
ATOM   8254 O "O3'" . U   C 2 125 ? 151.047 119.915 125.279 1.00 78.33  ? 125 U   C "O3'" 1 
ATOM   8255 C "C2'" . U   C 2 125 ? 149.528 117.975 125.322 1.00 78.33  ? 125 U   C "C2'" 1 
ATOM   8256 O "O2'" . U   C 2 125 ? 150.527 117.316 126.086 1.00 78.33  ? 125 U   C "O2'" 1 
ATOM   8257 C "C1'" . U   C 2 125 ? 148.183 117.791 126.026 1.00 78.33  ? 125 U   C "C1'" 1 
ATOM   8258 N N1    . U   C 2 125 ? 147.050 117.700 125.075 1.00 78.33  ? 125 U   C N1    1 
ATOM   8259 C C2    . U   C 2 125 ? 146.566 116.440 124.788 1.00 78.33  ? 125 U   C C2    1 
ATOM   8260 O O2    . U   C 2 125 ? 147.029 115.428 125.283 1.00 78.33  ? 125 U   C O2    1 
ATOM   8261 N N3    . U   C 2 125 ? 145.514 116.403 123.907 1.00 78.33  ? 125 U   C N3    1 
ATOM   8262 C C4    . U   C 2 125 ? 144.910 117.477 123.288 1.00 78.33  ? 125 U   C C4    1 
ATOM   8263 O O4    . U   C 2 125 ? 143.972 117.283 122.514 1.00 78.33  ? 125 U   C O4    1 
ATOM   8264 C C5    . U   C 2 125 ? 145.467 118.747 123.632 1.00 78.33  ? 125 U   C C5    1 
ATOM   8265 C C6    . U   C 2 125 ? 146.491 118.811 124.489 1.00 78.33  ? 125 U   C C6    1 
ATOM   8266 P P     . A   C 2 126 ? 151.471 120.902 124.086 1.00 84.46  ? 126 A   C P     1 
ATOM   8267 O OP1   . A   C 2 126 ? 152.442 121.889 124.622 1.00 84.46  ? 126 A   C OP1   1 
ATOM   8268 O OP2   . A   C 2 126 ? 150.230 121.375 123.422 1.00 84.46  ? 126 A   C OP2   1 
ATOM   8269 O "O5'" . A   C 2 126 ? 152.241 119.949 123.071 1.00 84.46  ? 126 A   C "O5'" 1 
ATOM   8270 C "C5'" . A   C 2 126 ? 153.311 119.134 123.521 1.00 84.46  ? 126 A   C "C5'" 1 
ATOM   8271 C "C4'" . A   C 2 126 ? 153.449 117.895 122.679 1.00 84.46  ? 126 A   C "C4'" 1 
ATOM   8272 O "O4'" . A   C 2 126 ? 152.312 117.024 122.897 1.00 84.46  ? 126 A   C "O4'" 1 
ATOM   8273 C "C3'" . A   C 2 126 ? 153.463 118.122 121.178 1.00 84.46  ? 126 A   C "C3'" 1 
ATOM   8274 O "O3'" . A   C 2 126 ? 154.741 118.503 120.704 1.00 84.46  ? 126 A   C "O3'" 1 
ATOM   8275 C "C2'" . A   C 2 126 ? 152.980 116.787 120.629 1.00 84.46  ? 126 A   C "C2'" 1 
ATOM   8276 O "O2'" . A   C 2 126 ? 154.040 115.843 120.607 1.00 84.46  ? 126 A   C "O2'" 1 
ATOM   8277 C "C1'" . A   C 2 126 ? 151.976 116.360 121.699 1.00 84.46  ? 126 A   C "C1'" 1 
ATOM   8278 N N9    . A   C 2 126 ? 150.585 116.704 121.350 1.00 84.46  ? 126 A   C N9    1 
ATOM   8279 C C8    . A   C 2 126 ? 149.767 117.597 121.991 1.00 84.46  ? 126 A   C C8    1 
ATOM   8280 N N7    . A   C 2 126 ? 148.569 117.691 121.473 1.00 84.46  ? 126 A   C N7    1 
ATOM   8281 C C5    . A   C 2 126 ? 148.598 116.793 120.419 1.00 84.46  ? 126 A   C C5    1 
ATOM   8282 C C6    . A   C 2 126 ? 147.634 116.429 119.468 1.00 84.46  ? 126 A   C C6    1 
ATOM   8283 N N6    . A   C 2 126 ? 146.401 116.938 119.430 1.00 84.46  ? 126 A   C N6    1 
ATOM   8284 N N1    . A   C 2 126 ? 147.981 115.503 118.549 1.00 84.46  ? 126 A   C N1    1 
ATOM   8285 C C2    . A   C 2 126 ? 149.214 114.986 118.590 1.00 84.46  ? 126 A   C C2    1 
ATOM   8286 N N3    . A   C 2 126 ? 150.209 115.252 119.432 1.00 84.46  ? 126 A   C N3    1 
ATOM   8287 C C4    . A   C 2 126 ? 149.831 116.173 120.333 1.00 84.46  ? 126 A   C C4    1 
ATOM   8288 P P     . C   C 2 127 ? 154.877 119.502 119.456 1.00 87.53  ? 127 C   C P     1 
ATOM   8289 O OP1   . C   C 2 127 ? 156.281 119.982 119.400 1.00 87.53  ? 127 C   C OP1   1 
ATOM   8290 O OP2   . C   C 2 127 ? 153.769 120.487 119.531 1.00 87.53  ? 127 C   C OP2   1 
ATOM   8291 O "O5'" . C   C 2 127 ? 154.622 118.565 118.195 1.00 87.53  ? 127 C   C "O5'" 1 
ATOM   8292 C "C5'" . C   C 2 127 ? 155.392 117.390 117.995 1.00 87.53  ? 127 C   C "C5'" 1 
ATOM   8293 C "C4'" . C   C 2 127 ? 154.892 116.608 116.808 1.00 87.53  ? 127 C   C "C4'" 1 
ATOM   8294 O "O4'" . C   C 2 127 ? 153.647 115.945 117.143 1.00 87.53  ? 127 C   C "O4'" 1 
ATOM   8295 C "C3'" . C   C 2 127 ? 154.554 117.433 115.578 1.00 87.53  ? 127 C   C "C3'" 1 
ATOM   8296 O "O3'" . C   C 2 127 ? 155.698 117.758 114.809 1.00 87.53  ? 127 C   C "O3'" 1 
ATOM   8297 C "C2'" . C   C 2 127 ? 153.550 116.552 114.847 1.00 87.53  ? 127 C   C "C2'" 1 
ATOM   8298 O "O2'" . C   C 2 127 ? 154.216 115.526 114.126 1.00 87.53  ? 127 C   C "O2'" 1 
ATOM   8299 C "C1'" . C   C 2 127 ? 152.799 115.912 116.014 1.00 87.53  ? 127 C   C "C1'" 1 
ATOM   8300 N N1    . C   C 2 127 ? 151.542 116.621 116.350 1.00 87.53  ? 127 C   C N1    1 
ATOM   8301 C C2    . C   C 2 127 ? 150.380 116.361 115.615 1.00 87.53  ? 127 C   C C2    1 
ATOM   8302 O O2    . C   C 2 127 ? 150.418 115.554 114.675 1.00 87.53  ? 127 C   C O2    1 
ATOM   8303 N N3    . C   C 2 127 ? 149.233 117.004 115.935 1.00 87.53  ? 127 C   C N3    1 
ATOM   8304 C C4    . C   C 2 127 ? 149.218 117.871 116.949 1.00 87.53  ? 127 C   C C4    1 
ATOM   8305 N N4    . C   C 2 127 ? 148.067 118.483 117.233 1.00 87.53  ? 127 C   C N4    1 
ATOM   8306 C C5    . C   C 2 127 ? 150.381 118.150 117.719 1.00 87.53  ? 127 C   C C5    1 
ATOM   8307 C C6    . C   C 2 127 ? 151.507 117.507 117.390 1.00 87.53  ? 127 C   C C6    1 
ATOM   8308 P P     . C   C 2 128 ? 155.785 119.167 114.045 1.00 97.70  ? 128 C   C P     1 
ATOM   8309 O OP1   . C   C 2 128 ? 157.205 119.409 113.683 1.00 97.70  ? 128 C   C OP1   1 
ATOM   8310 O OP2   . C   C 2 128 ? 155.054 120.177 114.852 1.00 97.70  ? 128 C   C OP2   1 
ATOM   8311 O "O5'" . C   C 2 128 ? 154.965 118.919 112.704 1.00 97.70  ? 128 C   C "O5'" 1 
ATOM   8312 C "C5'" . C   C 2 128 ? 155.246 117.797 111.880 1.00 97.70  ? 128 C   C "C5'" 1 
ATOM   8313 C "C4'" . C   C 2 128 ? 154.089 117.480 110.968 1.00 97.70  ? 128 C   C "C4'" 1 
ATOM   8314 O "O4'" . C   C 2 128 ? 152.945 117.056 111.752 1.00 97.70  ? 128 C   C "O4'" 1 
ATOM   8315 C "C3'" . C   C 2 128 ? 153.560 118.642 110.144 1.00 97.70  ? 128 C   C "C3'" 1 
ATOM   8316 O "O3'" . C   C 2 128 ? 154.338 118.892 108.988 1.00 97.70  ? 128 C   C "O3'" 1 
ATOM   8317 C "C2'" . C   C 2 128 ? 152.130 118.213 109.844 1.00 97.70  ? 128 C   C "C2'" 1 
ATOM   8318 O "O2'" . C   C 2 128 ? 152.102 117.268 108.785 1.00 97.70  ? 128 C   C "O2'" 1 
ATOM   8319 C "C1'" . C   C 2 128 ? 151.751 117.495 111.140 1.00 97.70  ? 128 C   C "C1'" 1 
ATOM   8320 N N1    . C   C 2 128 ? 151.030 118.378 112.085 1.00 97.70  ? 128 C   C N1    1 
ATOM   8321 C C2    . C   C 2 128 ? 149.652 118.544 111.928 1.00 97.70  ? 128 C   C C2    1 
ATOM   8322 O O2    . C   C 2 128 ? 149.084 117.951 111.002 1.00 97.70  ? 128 C   C O2    1 
ATOM   8323 N N3    . C   C 2 128 ? 148.974 119.343 112.784 1.00 97.70  ? 128 C   C N3    1 
ATOM   8324 C C4    . C   C 2 128 ? 149.625 119.964 113.769 1.00 97.70  ? 128 C   C C4    1 
ATOM   8325 N N4    . C   C 2 128 ? 148.923 120.744 114.594 1.00 97.70  ? 128 C   C N4    1 
ATOM   8326 C C5    . C   C 2 128 ? 151.029 119.813 113.955 1.00 97.70  ? 128 C   C C5    1 
ATOM   8327 C C6    . C   C 2 128 ? 151.684 119.019 113.100 1.00 97.70  ? 128 C   C C6    1 
ATOM   8328 P P     . G   C 2 129 ? 154.698 120.400 108.570 1.00 112.72 ? 129 G   C P     1 
ATOM   8329 O OP1   . G   C 2 129 ? 155.747 120.349 107.520 1.00 112.72 ? 129 G   C OP1   1 
ATOM   8330 O OP2   . G   C 2 129 ? 154.938 121.180 109.811 1.00 112.72 ? 129 G   C OP2   1 
ATOM   8331 O "O5'" . G   C 2 129 ? 153.357 120.938 107.902 1.00 112.72 ? 129 G   C "O5'" 1 
ATOM   8332 C "C5'" . G   C 2 129 ? 152.766 120.251 106.810 1.00 112.72 ? 129 G   C "C5'" 1 
ATOM   8333 C "C4'" . G   C 2 129 ? 151.330 120.662 106.614 1.00 112.72 ? 129 G   C "C4'" 1 
ATOM   8334 O "O4'" . G   C 2 129 ? 150.520 120.162 107.708 1.00 112.72 ? 129 G   C "O4'" 1 
ATOM   8335 C "C3'" . G   C 2 129 ? 151.064 122.158 106.613 1.00 112.72 ? 129 G   C "C3'" 1 
ATOM   8336 O "O3'" . G   C 2 129 ? 151.348 122.763 105.364 1.00 112.72 ? 129 G   C "O3'" 1 
ATOM   8337 C "C2'" . G   C 2 129 ? 149.597 122.237 107.011 1.00 112.72 ? 129 G   C "C2'" 1 
ATOM   8338 O "O2'" . G   C 2 129 ? 148.760 121.950 105.901 1.00 112.72 ? 129 G   C "O2'" 1 
ATOM   8339 C "C1'" . G   C 2 129 ? 149.490 121.081 108.004 1.00 112.72 ? 129 G   C "C1'" 1 
ATOM   8340 N N9    . G   C 2 129 ? 149.640 121.519 109.405 1.00 112.72 ? 129 G   C N9    1 
ATOM   8341 C C8    . G   C 2 129 ? 150.742 121.349 110.205 1.00 112.72 ? 129 G   C C8    1 
ATOM   8342 N N7    . G   C 2 129 ? 150.582 121.826 111.408 1.00 112.72 ? 129 G   C N7    1 
ATOM   8343 C C5    . G   C 2 129 ? 149.294 122.339 111.405 1.00 112.72 ? 129 G   C C5    1 
ATOM   8344 C C6    . G   C 2 129 ? 148.563 122.984 112.434 1.00 112.72 ? 129 G   C C6    1 
ATOM   8345 O O6    . G   C 2 129 ? 148.919 123.239 113.590 1.00 112.72 ? 129 G   C O6    1 
ATOM   8346 N N1    . G   C 2 129 ? 147.293 123.348 112.004 1.00 112.72 ? 129 G   C N1    1 
ATOM   8347 C C2    . G   C 2 129 ? 146.788 123.117 110.750 1.00 112.72 ? 129 G   C C2    1 
ATOM   8348 N N2    . G   C 2 129 ? 145.535 123.540 110.535 1.00 112.72 ? 129 G   C N2    1 
ATOM   8349 N N3    . G   C 2 129 ? 147.458 122.514 109.782 1.00 112.72 ? 129 G   C N3    1 
ATOM   8350 C C4    . G   C 2 129 ? 148.696 122.155 110.176 1.00 112.72 ? 129 G   C C4    1 
ATOM   8351 P P     . U   C 2 130 ? 151.781 124.307 105.297 1.00 127.64 ? 130 U   C P     1 
ATOM   8352 O OP1   . U   C 2 130 ? 152.283 124.586 103.928 1.00 127.64 ? 130 U   C OP1   1 
ATOM   8353 O OP2   . U   C 2 130 ? 152.646 124.592 106.470 1.00 127.64 ? 130 U   C OP2   1 
ATOM   8354 O "O5'" . U   C 2 130 ? 150.412 125.095 105.492 1.00 127.64 ? 130 U   C "O5'" 1 
ATOM   8355 C "C5'" . U   C 2 130 ? 149.305 124.854 104.635 1.00 127.64 ? 130 U   C "C5'" 1 
ATOM   8356 C "C4'" . U   C 2 130 ? 148.049 125.487 105.175 1.00 127.64 ? 130 U   C "C4'" 1 
ATOM   8357 O "O4'" . U   C 2 130 ? 147.638 124.814 106.393 1.00 127.64 ? 130 U   C "O4'" 1 
ATOM   8358 C "C3'" . U   C 2 130 ? 148.174 126.944 105.584 1.00 127.64 ? 130 U   C "C3'" 1 
ATOM   8359 O "O3'" . U   C 2 130 ? 148.093 127.827 104.482 1.00 127.64 ? 130 U   C "O3'" 1 
ATOM   8360 C "C2'" . U   C 2 130 ? 147.043 127.106 106.590 1.00 127.64 ? 130 U   C "C2'" 1 
ATOM   8361 O "O2'" . U   C 2 130 ? 145.798 127.256 105.925 1.00 127.64 ? 130 U   C "O2'" 1 
ATOM   8362 C "C1'" . U   C 2 130 ? 147.058 125.744 107.284 1.00 127.64 ? 130 U   C "C1'" 1 
ATOM   8363 N N1    . U   C 2 130 ? 147.843 125.749 108.541 1.00 127.64 ? 130 U   C N1    1 
ATOM   8364 C C2    . U   C 2 130 ? 147.226 126.209 109.687 1.00 127.64 ? 130 U   C C2    1 
ATOM   8365 O O2    . U   C 2 130 ? 146.078 126.618 109.699 1.00 127.64 ? 130 U   C O2    1 
ATOM   8366 N N3    . U   C 2 130 ? 148.001 126.179 110.821 1.00 127.64 ? 130 U   C N3    1 
ATOM   8367 C C4    . U   C 2 130 ? 149.304 125.741 110.927 1.00 127.64 ? 130 U   C C4    1 
ATOM   8368 O O4    . U   C 2 130 ? 149.869 125.776 112.021 1.00 127.64 ? 130 U   C O4    1 
ATOM   8369 C C5    . U   C 2 130 ? 149.873 125.275 109.701 1.00 127.64 ? 130 U   C C5    1 
ATOM   8370 C C6    . U   C 2 130 ? 149.141 125.294 108.582 1.00 127.64 ? 130 U   C C6    1 
ATOM   8371 P P     . A   C 2 131 ? 149.308 128.828 104.165 1.00 141.99 ? 131 A   C P     1 
ATOM   8372 O OP1   . A   C 2 131 ? 149.370 129.026 102.695 1.00 141.99 ? 131 A   C OP1   1 
ATOM   8373 O OP2   . A   C 2 131 ? 150.508 128.345 104.894 1.00 141.99 ? 131 A   C OP2   1 
ATOM   8374 O "O5'" . A   C 2 131 ? 148.844 130.197 104.829 1.00 141.99 ? 131 A   C "O5'" 1 
ATOM   8375 C "C5'" . A   C 2 131 ? 147.577 130.752 104.516 1.00 141.99 ? 131 A   C "C5'" 1 
ATOM   8376 C "C4'" . A   C 2 131 ? 146.974 131.464 105.698 1.00 141.99 ? 131 A   C "C4'" 1 
ATOM   8377 O "O4'" . A   C 2 131 ? 146.666 130.516 106.750 1.00 141.99 ? 131 A   C "O4'" 1 
ATOM   8378 C "C3'" . A   C 2 131 ? 147.858 132.490 106.384 1.00 141.99 ? 131 A   C "C3'" 1 
ATOM   8379 O "O3'" . A   C 2 131 ? 147.904 133.724 105.692 1.00 141.99 ? 131 A   C "O3'" 1 
ATOM   8380 C "C2'" . A   C 2 131 ? 147.235 132.588 107.771 1.00 141.99 ? 131 A   C "C2'" 1 
ATOM   8381 O "O2'" . A   C 2 131 ? 146.077 133.408 107.743 1.00 141.99 ? 131 A   C "O2'" 1 
ATOM   8382 C "C1'" . A   C 2 131 ? 146.793 131.144 108.010 1.00 141.99 ? 131 A   C "C1'" 1 
ATOM   8383 N N9    . A   C 2 131 ? 147.744 130.384 108.844 1.00 141.99 ? 131 A   C N9    1 
ATOM   8384 C C8    . A   C 2 131 ? 148.627 129.402 108.469 1.00 141.99 ? 131 A   C C8    1 
ATOM   8385 N N7    . A   C 2 131 ? 149.327 128.910 109.464 1.00 141.99 ? 131 A   C N7    1 
ATOM   8386 C C5    . A   C 2 131 ? 148.873 129.615 110.570 1.00 141.99 ? 131 A   C C5    1 
ATOM   8387 C C6    . A   C 2 131 ? 149.214 129.570 111.934 1.00 141.99 ? 131 A   C C6    1 
ATOM   8388 N N6    . A   C 2 131 ? 150.134 128.750 112.445 1.00 141.99 ? 131 A   C N6    1 
ATOM   8389 N N1    . A   C 2 131 ? 148.567 130.409 112.771 1.00 141.99 ? 131 A   C N1    1 
ATOM   8390 C C2    . A   C 2 131 ? 147.644 131.234 112.264 1.00 141.99 ? 131 A   C C2    1 
ATOM   8391 N N3    . A   C 2 131 ? 147.235 131.370 111.006 1.00 141.99 ? 131 A   C N3    1 
ATOM   8392 C C4    . A   C 2 131 ? 147.897 130.522 110.201 1.00 141.99 ? 131 A   C C4    1 
ATOM   8393 P P     . C   C 2 132 ? 149.182 134.684 105.841 1.00 149.03 ? 132 C   C P     1 
ATOM   8394 O OP1   . C   C 2 132 ? 149.133 135.693 104.753 1.00 149.03 ? 132 C   C OP1   1 
ATOM   8395 O OP2   . C   C 2 132 ? 150.384 133.824 105.993 1.00 149.03 ? 132 C   C OP2   1 
ATOM   8396 O "O5'" . C   C 2 132 ? 148.936 135.433 107.224 1.00 149.03 ? 132 C   C "O5'" 1 
ATOM   8397 C "C5'" . C   C 2 132 ? 147.717 136.117 107.474 1.00 149.03 ? 132 C   C "C5'" 1 
ATOM   8398 C "C4'" . C   C 2 132 ? 147.591 136.495 108.927 1.00 149.03 ? 132 C   C "C4'" 1 
ATOM   8399 O "O4'" . C   C 2 132 ? 147.433 135.304 109.739 1.00 149.03 ? 132 C   C "O4'" 1 
ATOM   8400 C "C3'" . C   C 2 132 ? 148.799 137.193 109.526 1.00 149.03 ? 132 C   C "C3'" 1 
ATOM   8401 O "O3'" . C   C 2 132 ? 148.831 138.575 109.219 1.00 149.03 ? 132 C   C "O3'" 1 
ATOM   8402 C "C2'" . C   C 2 132 ? 148.656 136.897 111.014 1.00 149.03 ? 132 C   C "C2'" 1 
ATOM   8403 O "O2'" . C   C 2 132 ? 147.710 137.770 111.611 1.00 149.03 ? 132 C   C "O2'" 1 
ATOM   8404 C "C1'" . C   C 2 132 ? 148.064 135.485 110.990 1.00 149.03 ? 132 C   C "C1'" 1 
ATOM   8405 N N1    . C   C 2 132 ? 149.089 134.429 111.162 1.00 149.03 ? 132 C   C N1    1 
ATOM   8406 C C2    . C   C 2 132 ? 149.563 134.128 112.445 1.00 149.03 ? 132 C   C C2    1 
ATOM   8407 O O2    . C   C 2 132 ? 149.118 134.766 113.410 1.00 149.03 ? 132 C   C O2    1 
ATOM   8408 N N3    . C   C 2 132 ? 150.492 133.155 112.594 1.00 149.03 ? 132 C   C N3    1 
ATOM   8409 C C4    . C   C 2 132 ? 150.944 132.492 111.528 1.00 149.03 ? 132 C   C C4    1 
ATOM   8410 N N4    . C   C 2 132 ? 151.860 131.539 111.710 1.00 149.03 ? 132 C   C N4    1 
ATOM   8411 C C5    . C   C 2 132 ? 150.475 132.775 110.215 1.00 149.03 ? 132 C   C C5    1 
ATOM   8412 C C6    . C   C 2 132 ? 149.558 133.738 110.082 1.00 149.03 ? 132 C   C C6    1 
ATOM   8413 P P     . A   C 2 133 ? 150.210 139.272 108.785 1.00 165.08 ? 133 A   C P     1 
ATOM   8414 O OP1   . A   C 2 133 ? 149.890 140.582 108.163 1.00 165.08 ? 133 A   C OP1   1 
ATOM   8415 O OP2   . A   C 2 133 ? 151.015 138.278 108.031 1.00 165.08 ? 133 A   C OP2   1 
ATOM   8416 O "O5'" . A   C 2 133 ? 150.938 139.548 110.171 1.00 165.08 ? 133 A   C "O5'" 1 
ATOM   8417 C "C5'" . A   C 2 133 ? 150.261 140.220 111.222 1.00 165.08 ? 133 A   C "C5'" 1 
ATOM   8418 C "C4'" . A   C 2 133 ? 151.051 140.165 112.503 1.00 165.08 ? 133 A   C "C4'" 1 
ATOM   8419 O "O4'" . A   C 2 133 ? 150.789 138.920 113.198 1.00 165.08 ? 133 A   C "O4'" 1 
ATOM   8420 C "C3'" . A   C 2 133 ? 152.561 140.185 112.346 1.00 165.08 ? 133 A   C "C3'" 1 
ATOM   8421 O "O3'" . A   C 2 133 ? 153.076 141.483 112.116 1.00 165.08 ? 133 A   C "O3'" 1 
ATOM   8422 C "C2'" . A   C 2 133 ? 153.035 139.553 113.647 1.00 165.08 ? 133 A   C "C2'" 1 
ATOM   8423 O "O2'" . A   C 2 133 ? 152.984 140.493 114.710 1.00 165.08 ? 133 A   C "O2'" 1 
ATOM   8424 C "C1'" . A   C 2 133 ? 151.952 138.498 113.881 1.00 165.08 ? 133 A   C "C1'" 1 
ATOM   8425 N N9    . A   C 2 133 ? 152.349 137.173 113.370 1.00 165.08 ? 133 A   C N9    1 
ATOM   8426 C C8    . A   C 2 133 ? 151.932 136.541 112.224 1.00 165.08 ? 133 A   C C8    1 
ATOM   8427 N N7    . A   C 2 133 ? 152.473 135.359 112.046 1.00 165.08 ? 133 A   C N7    1 
ATOM   8428 C C5    . A   C 2 133 ? 153.301 135.201 113.148 1.00 165.08 ? 133 A   C C5    1 
ATOM   8429 C C6    . A   C 2 133 ? 154.156 134.160 113.554 1.00 165.08 ? 133 A   C C6    1 
ATOM   8430 N N6    . A   C 2 133 ? 154.328 133.028 112.870 1.00 165.08 ? 133 A   C N6    1 
ATOM   8431 N N1    . A   C 2 133 ? 154.840 134.320 114.708 1.00 165.08 ? 133 A   C N1    1 
ATOM   8432 C C2    . A   C 2 133 ? 154.669 135.455 115.399 1.00 165.08 ? 133 A   C C2    1 
ATOM   8433 N N3    . A   C 2 133 ? 153.899 136.504 115.121 1.00 165.08 ? 133 A   C N3    1 
ATOM   8434 C C4    . A   C 2 133 ? 153.233 136.311 113.970 1.00 165.08 ? 133 A   C C4    1 
ATOM   8435 P P     . G   C 2 134 ? 154.372 141.679 111.188 1.00 176.26 ? 134 G   C P     1 
ATOM   8436 O OP1   . G   C 2 134 ? 154.413 143.095 110.743 1.00 176.26 ? 134 G   C OP1   1 
ATOM   8437 O OP2   . G   C 2 134 ? 154.385 140.592 110.177 1.00 176.26 ? 134 G   C OP2   1 
ATOM   8438 O "O5'" . G   C 2 134 ? 155.587 141.439 112.188 1.00 176.26 ? 134 G   C "O5'" 1 
ATOM   8439 C "C5'" . G   C 2 134 ? 155.671 142.162 113.405 1.00 176.26 ? 134 G   C "C5'" 1 
ATOM   8440 C "C4'" . G   C 2 134 ? 156.578 141.483 114.398 1.00 176.26 ? 134 G   C "C4'" 1 
ATOM   8441 O "O4'" . G   C 2 134 ? 156.018 140.205 114.792 1.00 176.26 ? 134 G   C "O4'" 1 
ATOM   8442 C "C3'" . G   C 2 134 ? 157.970 141.134 113.900 1.00 176.26 ? 134 G   C "C3'" 1 
ATOM   8443 O "O3'" . G   C 2 134 ? 158.849 142.245 113.912 1.00 176.26 ? 134 G   C "O3'" 1 
ATOM   8444 C "C2'" . G   C 2 134 ? 158.388 140.012 114.842 1.00 176.26 ? 134 G   C "C2'" 1 
ATOM   8445 O "O2'" . G   C 2 134 ? 158.823 140.538 116.087 1.00 176.26 ? 134 G   C "O2'" 1 
ATOM   8446 C "C1'" . G   C 2 134 ? 157.058 139.288 115.063 1.00 176.26 ? 134 G   C "C1'" 1 
ATOM   8447 N N9    . G   C 2 134 ? 156.904 138.113 114.184 1.00 176.26 ? 134 G   C N9    1 
ATOM   8448 C C8    . G   C 2 134 ? 156.091 137.982 113.085 1.00 176.26 ? 134 G   C C8    1 
ATOM   8449 N N7    . G   C 2 134 ? 156.174 136.807 112.522 1.00 176.26 ? 134 G   C N7    1 
ATOM   8450 C C5    . G   C 2 134 ? 157.099 136.118 113.295 1.00 176.26 ? 134 G   C C5    1 
ATOM   8451 C C6    . G   C 2 134 ? 157.600 134.794 113.179 1.00 176.26 ? 134 G   C C6    1 
ATOM   8452 O O6    . G   C 2 134 ? 157.323 133.932 112.337 1.00 176.26 ? 134 G   C O6    1 
ATOM   8453 N N1    . G   C 2 134 ? 158.523 134.506 114.180 1.00 176.26 ? 134 G   C N1    1 
ATOM   8454 C C2    . G   C 2 134 ? 158.912 135.377 115.169 1.00 176.26 ? 134 G   C C2    1 
ATOM   8455 N N2    . G   C 2 134 ? 159.813 134.926 116.054 1.00 176.26 ? 134 G   C N2    1 
ATOM   8456 N N3    . G   C 2 134 ? 158.451 136.610 115.288 1.00 176.26 ? 134 G   C N3    1 
ATOM   8457 C C4    . G   C 2 134 ? 157.555 136.911 114.326 1.00 176.26 ? 134 G   C C4    1 
ATOM   8458 P P     . U   C 2 135 ? 160.037 142.352 112.835 1.00 193.14 ? 135 U   C P     1 
ATOM   8459 O OP1   . U   C 2 135 ? 160.541 143.748 112.843 1.00 193.14 ? 135 U   C OP1   1 
ATOM   8460 O OP2   . U   C 2 135 ? 159.565 141.747 111.564 1.00 193.14 ? 135 U   C OP2   1 
ATOM   8461 O "O5'" . U   C 2 135 ? 161.177 141.415 113.433 1.00 193.14 ? 135 U   C "O5'" 1 
ATOM   8462 C "C5'" . U   C 2 135 ? 161.674 141.626 114.746 1.00 193.14 ? 135 U   C "C5'" 1 
ATOM   8463 C "C4'" . U   C 2 135 ? 162.529 140.473 115.203 1.00 193.14 ? 135 U   C "C4'" 1 
ATOM   8464 O "O4'" . U   C 2 135 ? 161.713 139.281 115.348 1.00 193.14 ? 135 U   C "O4'" 1 
ATOM   8465 C "C3'" . U   C 2 135 ? 163.632 140.048 114.248 1.00 193.14 ? 135 U   C "C3'" 1 
ATOM   8466 O "O3'" . U   C 2 135 ? 164.781 140.874 114.327 1.00 193.14 ? 135 U   C "O3'" 1 
ATOM   8467 C "C2'" . U   C 2 135 ? 163.882 138.603 114.654 1.00 193.14 ? 135 U   C "C2'" 1 
ATOM   8468 O "O2'" . U   C 2 135 ? 164.669 138.541 115.834 1.00 193.14 ? 135 U   C "O2'" 1 
ATOM   8469 C "C1'" . U   C 2 135 ? 162.465 138.138 114.994 1.00 193.14 ? 135 U   C "C1'" 1 
ATOM   8470 N N1    . U   C 2 135 ? 161.804 137.473 113.846 1.00 193.14 ? 135 U   C N1    1 
ATOM   8471 C C2    . U   C 2 135 ? 162.162 136.167 113.568 1.00 193.14 ? 135 U   C C2    1 
ATOM   8472 O O2    . U   C 2 135 ? 162.989 135.554 114.219 1.00 193.14 ? 135 U   C O2    1 
ATOM   8473 N N3    . U   C 2 135 ? 161.521 135.599 112.494 1.00 193.14 ? 135 U   C N3    1 
ATOM   8474 C C4    . U   C 2 135 ? 160.571 136.197 111.690 1.00 193.14 ? 135 U   C C4    1 
ATOM   8475 O O4    . U   C 2 135 ? 160.075 135.563 110.757 1.00 193.14 ? 135 U   C O4    1 
ATOM   8476 C C5    . U   C 2 135 ? 160.253 137.546 112.043 1.00 193.14 ? 135 U   C C5    1 
ATOM   8477 C C6    . U   C 2 135 ? 160.864 138.123 113.082 1.00 193.14 ? 135 U   C C6    1 
ATOM   8478 P P     . G   C 2 136 ? 165.164 141.839 113.101 1.00 207.61 ? 136 G   C P     1 
ATOM   8479 O OP1   . G   C 2 136 ? 165.760 143.080 113.660 1.00 207.61 ? 136 G   C OP1   1 
ATOM   8480 O OP2   . G   C 2 136 ? 163.986 141.931 112.201 1.00 207.61 ? 136 G   C OP2   1 
ATOM   8481 O "O5'" . G   C 2 136 ? 166.310 141.047 112.329 1.00 207.61 ? 136 G   C "O5'" 1 
ATOM   8482 C "C5'" . G   C 2 136 ? 167.574 140.825 112.936 1.00 207.61 ? 136 G   C "C5'" 1 
ATOM   8483 C "C4'" . G   C 2 136 ? 168.179 139.518 112.490 1.00 207.61 ? 136 G   C "C4'" 1 
ATOM   8484 O "O4'" . G   C 2 136 ? 167.301 138.423 112.850 1.00 207.61 ? 136 G   C "O4'" 1 
ATOM   8485 C "C3'" . G   C 2 136 ? 168.381 139.351 110.992 1.00 207.61 ? 136 G   C "C3'" 1 
ATOM   8486 O "O3'" . G   C 2 136 ? 169.554 139.989 110.519 1.00 207.61 ? 136 G   C "O3'" 1 
ATOM   8487 C "C2'" . G   C 2 136 ? 168.403 137.837 110.826 1.00 207.61 ? 136 G   C "C2'" 1 
ATOM   8488 O "O2'" . G   C 2 136 ? 169.671 137.310 111.188 1.00 207.61 ? 136 G   C "O2'" 1 
ATOM   8489 C "C1'" . G   C 2 136 ? 167.385 137.400 111.880 1.00 207.61 ? 136 G   C "C1'" 1 
ATOM   8490 N N9    . G   C 2 136 ? 166.045 137.167 111.309 1.00 207.61 ? 136 G   C N9    1 
ATOM   8491 C C8    . G   C 2 136 ? 164.922 137.948 111.439 1.00 207.61 ? 136 G   C C8    1 
ATOM   8492 N N7    . G   C 2 136 ? 163.883 137.456 110.819 1.00 207.61 ? 136 G   C N7    1 
ATOM   8493 C C5    . G   C 2 136 ? 164.347 136.279 110.248 1.00 207.61 ? 136 G   C C5    1 
ATOM   8494 C C6    . G   C 2 136 ? 163.682 135.310 109.451 1.00 207.61 ? 136 G   C C6    1 
ATOM   8495 O O6    . G   C 2 136 ? 162.505 135.288 109.073 1.00 207.61 ? 136 G   C O6    1 
ATOM   8496 N N1    . G   C 2 136 ? 164.536 134.272 109.086 1.00 207.61 ? 136 G   C N1    1 
ATOM   8497 C C2    . G   C 2 136 ? 165.861 134.178 109.440 1.00 207.61 ? 136 G   C C2    1 
ATOM   8498 N N2    . G   C 2 136 ? 166.534 133.105 108.998 1.00 207.61 ? 136 G   C N2    1 
ATOM   8499 N N3    . G   C 2 136 ? 166.489 135.074 110.180 1.00 207.61 ? 136 G   C N3    1 
ATOM   8500 C C4    . G   C 2 136 ? 165.678 136.087 110.545 1.00 207.61 ? 136 G   C C4    1 
ATOM   8501 P P     . U   C 2 137 ? 169.680 140.410 108.974 1.00 213.66 ? 137 U   C P     1 
ATOM   8502 O OP1   . U   C 2 137 ? 170.881 141.271 108.829 1.00 213.66 ? 137 U   C OP1   1 
ATOM   8503 O OP2   . U   C 2 137 ? 168.357 140.911 108.525 1.00 213.66 ? 137 U   C OP2   1 
ATOM   8504 O "O5'" . U   C 2 137 ? 169.968 139.035 108.222 1.00 213.66 ? 137 U   C "O5'" 1 
ATOM   8505 C "C5'" . U   C 2 137 ? 171.132 138.274 108.510 1.00 213.66 ? 137 U   C "C5'" 1 
ATOM   8506 C "C4'" . U   C 2 137 ? 171.170 137.001 107.703 1.00 213.66 ? 137 U   C "C4'" 1 
ATOM   8507 O "O4'" . U   C 2 137 ? 170.107 136.111 108.131 1.00 213.66 ? 137 U   C "O4'" 1 
ATOM   8508 C "C3'" . U   C 2 137 ? 170.941 137.161 106.210 1.00 213.66 ? 137 U   C "C3'" 1 
ATOM   8509 O "O3'" . U   C 2 137 ? 172.110 137.566 105.520 1.00 213.66 ? 137 U   C "O3'" 1 
ATOM   8510 C "C2'" . U   C 2 137 ? 170.431 135.785 105.797 1.00 213.66 ? 137 U   C "C2'" 1 
ATOM   8511 O "O2'" . U   C 2 137 ? 171.510 134.873 105.652 1.00 213.66 ? 137 U   C "O2'" 1 
ATOM   8512 C "C1'" . U   C 2 137 ? 169.617 135.379 107.027 1.00 213.66 ? 137 U   C "C1'" 1 
ATOM   8513 N N1    . U   C 2 137 ? 168.171 135.663 106.874 1.00 213.66 ? 137 U   C N1    1 
ATOM   8514 C C2    . U   C 2 137 ? 167.408 134.792 106.117 1.00 213.66 ? 137 U   C C2    1 
ATOM   8515 O O2    . U   C 2 137 ? 167.876 133.813 105.562 1.00 213.66 ? 137 U   C O2    1 
ATOM   8516 N N3    . U   C 2 137 ? 166.074 135.112 106.023 1.00 213.66 ? 137 U   C N3    1 
ATOM   8517 C C4    . U   C 2 137 ? 165.445 136.192 106.612 1.00 213.66 ? 137 U   C C4    1 
ATOM   8518 O O4    . U   C 2 137 ? 164.237 136.356 106.445 1.00 213.66 ? 137 U   C O4    1 
ATOM   8519 C C5    . U   C 2 137 ? 166.300 137.042 107.381 1.00 213.66 ? 137 U   C C5    1 
ATOM   8520 C C6    . U   C 2 137 ? 167.600 136.753 107.486 1.00 213.66 ? 137 U   C C6    1 
ATOM   8521 P P     . U   C 2 138 ? 172.005 138.580 104.280 1.00 218.29 ? 138 U   C P     1 
ATOM   8522 O OP1   . U   C 2 138 ? 173.367 139.097 103.991 1.00 218.29 ? 138 U   C OP1   1 
ATOM   8523 O OP2   . U   C 2 138 ? 170.900 139.533 104.557 1.00 218.29 ? 138 U   C OP2   1 
ATOM   8524 O "O5'" . U   C 2 138 ? 171.562 137.649 103.067 1.00 218.29 ? 138 U   C "O5'" 1 
ATOM   8525 C "C5'" . U   C 2 138 ? 172.310 136.490 102.730 1.00 218.29 ? 138 U   C "C5'" 1 
ATOM   8526 C "C4'" . U   C 2 138 ? 171.586 135.653 101.708 1.00 218.29 ? 138 U   C "C4'" 1 
ATOM   8527 O "O4'" . U   C 2 138 ? 170.420 135.037 102.317 1.00 218.29 ? 138 U   C "O4'" 1 
ATOM   8528 C "C3'" . U   C 2 138 ? 171.019 136.409 100.518 1.00 218.29 ? 138 U   C "C3'" 1 
ATOM   8529 O "O3'" . U   C 2 138 ? 171.985 136.707 99.524  1.00 218.29 ? 138 U   C "O3'" 1 
ATOM   8530 C "C2'" . U   C 2 138 ? 169.904 135.488 100.044 1.00 218.29 ? 138 U   C "C2'" 1 
ATOM   8531 O "O2'" . U   C 2 138 ? 170.434 134.395 99.309  1.00 218.29 ? 138 U   C "O2'" 1 
ATOM   8532 C "C1'" . U   C 2 138 ? 169.369 134.960 101.376 1.00 218.29 ? 138 U   C "C1'" 1 
ATOM   8533 N N1    . U   C 2 138 ? 168.228 135.765 101.870 1.00 218.29 ? 138 U   C N1    1 
ATOM   8534 C C2    . U   C 2 138 ? 166.969 135.436 101.405 1.00 218.29 ? 138 U   C C2    1 
ATOM   8535 O O2    . U   C 2 138 ? 166.775 134.521 100.625 1.00 218.29 ? 138 U   C O2    1 
ATOM   8536 N N3    . U   C 2 138 ? 165.944 136.213 101.887 1.00 218.29 ? 138 U   C N3    1 
ATOM   8537 C C4    . U   C 2 138 ? 166.052 137.269 102.771 1.00 218.29 ? 138 U   C C4    1 
ATOM   8538 O O4    . U   C 2 138 ? 165.043 137.882 103.122 1.00 218.29 ? 138 U   C O4    1 
ATOM   8539 C C5    . U   C 2 138 ? 167.386 137.550 103.205 1.00 218.29 ? 138 U   C C5    1 
ATOM   8540 C C6    . U   C 2 138 ? 168.401 136.808 102.752 1.00 218.29 ? 138 U   C C6    1 
ATOM   8541 P P     . G   C 2 139 ? 172.499 138.219 99.314  1.00 214.46 ? 139 G   C P     1 
ATOM   8542 O OP1   . G   C 2 139 ? 173.653 138.177 98.380  1.00 214.46 ? 139 G   C OP1   1 
ATOM   8543 O OP2   . G   C 2 139 ? 172.660 138.852 100.647 1.00 214.46 ? 139 G   C OP2   1 
ATOM   8544 O "O5'" . G   C 2 139 ? 171.294 138.952 98.571  1.00 214.46 ? 139 G   C "O5'" 1 
ATOM   8545 C "C5'" . G   C 2 139 ? 170.225 139.538 99.303  1.00 214.46 ? 139 G   C "C5'" 1 
ATOM   8546 C "C4'" . G   C 2 139 ? 168.892 139.034 98.812  1.00 214.46 ? 139 G   C "C4'" 1 
ATOM   8547 O "O4'" . G   C 2 139 ? 168.054 138.651 99.937  1.00 214.46 ? 139 G   C "O4'" 1 
ATOM   8548 C "C3'" . G   C 2 139 ? 168.035 140.029 98.049  1.00 214.46 ? 139 G   C "C3'" 1 
ATOM   8549 O "O3'" . G   C 2 139 ? 168.442 140.223 96.706  1.00 214.46 ? 139 G   C "O3'" 1 
ATOM   8550 C "C2'" . G   C 2 139 ? 166.646 139.429 98.195  1.00 214.46 ? 139 G   C "C2'" 1 
ATOM   8551 O "O2'" . G   C 2 139 ? 166.491 138.309 97.335  1.00 214.46 ? 139 G   C "O2'" 1 
ATOM   8552 C "C1'" . G   C 2 139 ? 166.700 138.926 99.637  1.00 214.46 ? 139 G   C "C1'" 1 
ATOM   8553 N N9    . G   C 2 139 ? 166.216 139.962 100.565 1.00 214.46 ? 139 G   C N9    1 
ATOM   8554 C C8    . G   C 2 139 ? 166.964 140.722 101.431 1.00 214.46 ? 139 G   C C8    1 
ATOM   8555 N N7    . G   C 2 139 ? 166.246 141.575 102.109 1.00 214.46 ? 139 G   C N7    1 
ATOM   8556 C C5    . G   C 2 139 ? 164.949 141.371 101.656 1.00 214.46 ? 139 G   C C5    1 
ATOM   8557 C C6    . G   C 2 139 ? 163.739 142.008 102.028 1.00 214.46 ? 139 G   C C6    1 
ATOM   8558 O O6    . G   C 2 139 ? 163.562 142.908 102.858 1.00 214.46 ? 139 G   C O6    1 
ATOM   8559 N N1    . G   C 2 139 ? 162.658 141.496 101.320 1.00 214.46 ? 139 G   C N1    1 
ATOM   8560 C C2    . G   C 2 139 ? 162.728 140.500 100.377 1.00 214.46 ? 139 G   C C2    1 
ATOM   8561 N N2    . G   C 2 139 ? 161.564 140.152 99.812  1.00 214.46 ? 139 G   C N2    1 
ATOM   8562 N N3    . G   C 2 139 ? 163.849 139.894 100.016 1.00 214.46 ? 139 G   C N3    1 
ATOM   8563 C C4    . G   C 2 139 ? 164.913 140.380 100.696 1.00 214.46 ? 139 G   C C4    1 
ATOM   8564 P P     . A   C 2 140 ? 168.531 141.715 96.114  1.00 214.24 ? 140 A   C P     1 
ATOM   8565 O OP1   . A   C 2 140 ? 168.526 141.625 94.632  1.00 214.24 ? 140 A   C OP1   1 
ATOM   8566 O OP2   . A   C 2 140 ? 169.644 142.416 96.804  1.00 214.24 ? 140 A   C OP2   1 
ATOM   8567 O "O5'" . A   C 2 140 ? 167.163 142.392 96.574  1.00 214.24 ? 140 A   C "O5'" 1 
ATOM   8568 C "C5'" . A   C 2 140 ? 167.083 143.788 96.823  1.00 214.24 ? 140 A   C "C5'" 1 
ATOM   8569 C "C4'" . A   C 2 140 ? 166.034 144.450 95.964  1.00 214.24 ? 140 A   C "C4'" 1 
ATOM   8570 O "O4'" . A   C 2 140 ? 166.403 144.333 94.567  1.00 214.24 ? 140 A   C "O4'" 1 
ATOM   8571 C "C3'" . A   C 2 140 ? 164.635 143.853 96.028  1.00 214.24 ? 140 A   C "C3'" 1 
ATOM   8572 O "O3'" . A   C 2 140 ? 163.895 144.295 97.154  1.00 214.24 ? 140 A   C "O3'" 1 
ATOM   8573 C "C2'" . A   C 2 140 ? 164.024 144.274 94.696  1.00 214.24 ? 140 A   C "C2'" 1 
ATOM   8574 O "O2'" . A   C 2 140 ? 163.544 145.609 94.763  1.00 214.24 ? 140 A   C "O2'" 1 
ATOM   8575 C "C1'" . A   C 2 140 ? 165.243 144.244 93.768  1.00 214.24 ? 140 A   C "C1'" 1 
ATOM   8576 N N9    . A   C 2 140 ? 165.313 143.025 92.933  1.00 214.24 ? 140 A   C N9    1 
ATOM   8577 C C8    . A   C 2 140 ? 165.259 142.996 91.561  1.00 214.24 ? 140 A   C C8    1 
ATOM   8578 N N7    . A   C 2 140 ? 165.343 141.797 91.044  1.00 214.24 ? 140 A   C N7    1 
ATOM   8579 C C5    . A   C 2 140 ? 165.464 140.970 92.150  1.00 214.24 ? 140 A   C C5    1 
ATOM   8580 C C6    . A   C 2 140 ? 165.593 139.574 92.268  1.00 214.24 ? 140 A   C C6    1 
ATOM   8581 N N6    . A   C 2 140 ? 165.623 138.745 91.222  1.00 214.24 ? 140 A   C N6    1 
ATOM   8582 N N1    . A   C 2 140 ? 165.692 139.051 93.509  1.00 214.24 ? 140 A   C N1    1 
ATOM   8583 C C2    . A   C 2 140 ? 165.663 139.886 94.554  1.00 214.24 ? 140 A   C C2    1 
ATOM   8584 N N3    . A   C 2 140 ? 165.545 141.211 94.567  1.00 214.24 ? 140 A   C N3    1 
ATOM   8585 C C4    . A   C 2 140 ? 165.447 141.707 93.322  1.00 214.24 ? 140 A   C C4    1 
ATOM   8586 P P     . A   C 2 141 ? 163.211 143.227 98.140  1.00 214.01 ? 141 A   C P     1 
ATOM   8587 O OP1   . A   C 2 141 ? 163.040 143.864 99.471  1.00 214.01 ? 141 A   C OP1   1 
ATOM   8588 O OP2   . A   C 2 141 ? 163.979 141.962 98.021  1.00 214.01 ? 141 A   C OP2   1 
ATOM   8589 O "O5'" . A   C 2 141 ? 161.765 142.982 97.516  1.00 214.01 ? 141 A   C "O5'" 1 
ATOM   8590 C "C5'" . A   C 2 141 ? 160.771 143.998 97.545  1.00 214.01 ? 141 A   C "C5'" 1 
ATOM   8591 C "C4'" . A   C 2 141 ? 159.707 143.755 96.504  1.00 214.01 ? 141 A   C "C4'" 1 
ATOM   8592 O "O4'" . A   C 2 141 ? 160.329 143.625 95.202  1.00 214.01 ? 141 A   C "O4'" 1 
ATOM   8593 C "C3'" . A   C 2 141 ? 158.895 142.477 96.667  1.00 214.01 ? 141 A   C "C3'" 1 
ATOM   8594 O "O3'" . A   C 2 141 ? 157.809 142.637 97.564  1.00 214.01 ? 141 A   C "O3'" 1 
ATOM   8595 C "C2'" . A   C 2 141 ? 158.448 142.166 95.242  1.00 214.01 ? 141 A   C "C2'" 1 
ATOM   8596 O "O2'" . A   C 2 141 ? 157.293 142.919 94.903  1.00 214.01 ? 141 A   C "O2'" 1 
ATOM   8597 C "C1'" . A   C 2 141 ? 159.625 142.690 94.417  1.00 214.01 ? 141 A   C "C1'" 1 
ATOM   8598 N N9    . A   C 2 141 ? 160.558 141.630 93.986  1.00 214.01 ? 141 A   C N9    1 
ATOM   8599 C C8    . A   C 2 141 ? 161.887 141.509 94.312  1.00 214.01 ? 141 A   C C8    1 
ATOM   8600 N N7    . A   C 2 141 ? 162.478 140.476 93.761  1.00 214.01 ? 141 A   C N7    1 
ATOM   8601 C C5    . A   C 2 141 ? 161.473 139.881 93.012  1.00 214.01 ? 141 A   C C5    1 
ATOM   8602 C C6    . A   C 2 141 ? 161.458 138.740 92.191  1.00 214.01 ? 141 A   C C6    1 
ATOM   8603 N N6    . A   C 2 141 ? 162.524 137.965 91.978  1.00 214.01 ? 141 A   C N6    1 
ATOM   8604 N N1    . A   C 2 141 ? 160.293 138.417 91.586  1.00 214.01 ? 141 A   C N1    1 
ATOM   8605 C C2    . A   C 2 141 ? 159.224 139.193 91.799  1.00 214.01 ? 141 A   C C2    1 
ATOM   8606 N N3    . A   C 2 141 ? 159.114 140.289 92.548  1.00 214.01 ? 141 A   C N3    1 
ATOM   8607 C C4    . A   C 2 141 ? 160.287 140.584 93.135  1.00 214.01 ? 141 A   C C4    1 
ATOM   8608 P P     . A   C 2 142 ? 157.642 141.672 98.839  1.00 212.84 ? 142 A   C P     1 
ATOM   8609 O OP1   . A   C 2 142 ? 156.502 142.177 99.646  1.00 212.84 ? 142 A   C OP1   1 
ATOM   8610 O OP2   . A   C 2 142 ? 158.975 141.514 99.472  1.00 212.84 ? 142 A   C OP2   1 
ATOM   8611 O "O5'" . A   C 2 142 ? 157.221 140.266 98.218  1.00 212.84 ? 142 A   C "O5'" 1 
ATOM   8612 C "C5'" . A   C 2 142 ? 156.075 140.132 97.388  1.00 212.84 ? 142 A   C "C5'" 1 
ATOM   8613 C "C4'" . A   C 2 142 ? 156.191 138.913 96.508  1.00 212.84 ? 142 A   C "C4'" 1 
ATOM   8614 O "O4'" . A   C 2 142 ? 157.293 139.100 95.581  1.00 212.84 ? 142 A   C "O4'" 1 
ATOM   8615 C "C3'" . A   C 2 142 ? 156.518 137.616 97.238  1.00 212.84 ? 142 A   C "C3'" 1 
ATOM   8616 O "O3'" . A   C 2 142 ? 155.360 136.962 97.729  1.00 212.84 ? 142 A   C "O3'" 1 
ATOM   8617 C "C2'" . A   C 2 142 ? 157.274 136.811 96.190  1.00 212.84 ? 142 A   C "C2'" 1 
ATOM   8618 O "O2'" . A   C 2 142 ? 156.372 136.204 95.276  1.00 212.84 ? 142 A   C "O2'" 1 
ATOM   8619 C "C1'" . A   C 2 142 ? 158.037 137.909 95.457  1.00 212.84 ? 142 A   C "C1'" 1 
ATOM   8620 N N9    . A   C 2 142 ? 159.368 138.161 96.039  1.00 212.84 ? 142 A   C N9    1 
ATOM   8621 C C8    . A   C 2 142 ? 159.673 139.170 96.916  1.00 212.84 ? 142 A   C C8    1 
ATOM   8622 N N7    . A   C 2 142 ? 160.925 139.204 97.283  1.00 212.84 ? 142 A   C N7    1 
ATOM   8623 C C5    . A   C 2 142 ? 161.492 138.144 96.597  1.00 212.84 ? 142 A   C C5    1 
ATOM   8624 C C6    . A   C 2 142 ? 162.807 137.659 96.571  1.00 212.84 ? 142 A   C C6    1 
ATOM   8625 N N6    . A   C 2 142 ? 163.795 138.210 97.282  1.00 212.84 ? 142 A   C N6    1 
ATOM   8626 N N1    . A   C 2 142 ? 163.061 136.586 95.789  1.00 212.84 ? 142 A   C N1    1 
ATOM   8627 C C2    . A   C 2 142 ? 162.048 136.053 95.090  1.00 212.84 ? 142 A   C C2    1 
ATOM   8628 N N3    . A   C 2 142 ? 160.768 136.422 95.033  1.00 212.84 ? 142 A   C N3    1 
ATOM   8629 C C4    . A   C 2 142 ? 160.550 137.490 95.821  1.00 212.84 ? 142 A   C C4    1 
ATOM   8630 P P     . A   C 2 143 ? 155.286 136.468 99.256  1.00 211.12 ? 143 A   C P     1 
ATOM   8631 O OP1   . A   C 2 143 ? 153.874 136.123 99.560  1.00 211.12 ? 143 A   C OP1   1 
ATOM   8632 O OP2   . A   C 2 143 ? 155.998 137.465 100.096 1.00 211.12 ? 143 A   C OP2   1 
ATOM   8633 O "O5'" . A   C 2 143 ? 156.133 135.120 99.268  1.00 211.12 ? 143 A   C "O5'" 1 
ATOM   8634 C "C5'" . A   C 2 143 ? 155.890 134.095 98.315  1.00 211.12 ? 143 A   C "C5'" 1 
ATOM   8635 C "C4'" . A   C 2 143 ? 157.132 133.278 98.069  1.00 211.12 ? 143 A   C "C4'" 1 
ATOM   8636 O "O4'" . A   C 2 143 ? 158.203 134.150 97.621  1.00 211.12 ? 143 A   C "O4'" 1 
ATOM   8637 C "C3'" . A   C 2 143 ? 157.710 132.575 99.288  1.00 211.12 ? 143 A   C "C3'" 1 
ATOM   8638 O "O3'" . A   C 2 143 ? 157.066 131.345 99.572  1.00 211.12 ? 143 A   C "O3'" 1 
ATOM   8639 C "C2'" . A   C 2 143 ? 159.180 132.430 98.926  1.00 211.12 ? 143 A   C "C2'" 1 
ATOM   8640 O "O2'" . A   C 2 143 ? 159.370 131.351 98.022  1.00 211.12 ? 143 A   C "O2'" 1 
ATOM   8641 C "C1'" . A   C 2 143 ? 159.432 133.737 98.177  1.00 211.12 ? 143 A   C "C1'" 1 
ATOM   8642 N N9    . A   C 2 143 ? 159.907 134.804 99.077  1.00 211.12 ? 143 A   C N9    1 
ATOM   8643 C C8    . A   C 2 143 ? 159.149 135.772 99.688  1.00 211.12 ? 143 A   C C8    1 
ATOM   8644 N N7    . A   C 2 143 ? 159.841 136.594 100.437 1.00 211.12 ? 143 A   C N7    1 
ATOM   8645 C C5    . A   C 2 143 ? 161.145 136.136 100.311 1.00 211.12 ? 143 A   C C5    1 
ATOM   8646 C C6    . A   C 2 143 ? 162.357 136.582 100.863 1.00 211.12 ? 143 A   C C6    1 
ATOM   8647 N N6    . A   C 2 143 ? 162.452 137.630 101.682 1.00 211.12 ? 143 A   C N6    1 
ATOM   8648 N N1    . A   C 2 143 ? 163.481 135.908 100.540 1.00 211.12 ? 143 A   C N1    1 
ATOM   8649 C C2    . A   C 2 143 ? 163.382 134.856 99.716  1.00 211.12 ? 143 A   C C2    1 
ATOM   8650 N N3    . A   C 2 143 ? 162.301 134.340 99.134  1.00 211.12 ? 143 A   C N3    1 
ATOM   8651 C C4    . A   C 2 143 ? 161.202 135.034 99.477  1.00 211.12 ? 143 A   C C4    1 
ATOM   8652 P P     . A   C 2 144 ? 156.996 130.798 101.080 1.00 211.12 ? 144 A   C P     1 
ATOM   8653 O OP1   . A   C 2 144 ? 156.019 129.681 101.121 1.00 211.12 ? 144 A   C OP1   1 
ATOM   8654 O OP2   . A   C 2 144 ? 156.820 131.961 101.986 1.00 211.12 ? 144 A   C OP2   1 
ATOM   8655 O "O5'" . A   C 2 144 ? 158.447 130.193 101.333 1.00 211.12 ? 144 A   C "O5'" 1 
ATOM   8656 C "C5'" . A   C 2 144 ? 158.972 129.183 100.484 1.00 211.12 ? 144 A   C "C5'" 1 
ATOM   8657 C "C4'" . A   C 2 144 ? 160.446 128.977 100.720 1.00 211.12 ? 144 A   C "C4'" 1 
ATOM   8658 O "O4'" . A   C 2 144 ? 161.189 130.139 100.271 1.00 211.12 ? 144 A   C "O4'" 1 
ATOM   8659 C "C3'" . A   C 2 144 ? 160.866 128.809 102.170 1.00 211.12 ? 144 A   C "C3'" 1 
ATOM   8660 O "O3'" . A   C 2 144 ? 160.652 127.494 102.653 1.00 211.12 ? 144 A   C "O3'" 1 
ATOM   8661 C "C2'" . A   C 2 144 ? 162.331 129.224 102.143 1.00 211.12 ? 144 A   C "C2'" 1 
ATOM   8662 O "O2'" . A   C 2 144 ? 163.142 128.169 101.645 1.00 211.12 ? 144 A   C "O2'" 1 
ATOM   8663 C "C1'" . A   C 2 144 ? 162.310 130.347 101.105 1.00 211.12 ? 144 A   C "C1'" 1 
ATOM   8664 N N9    . A   C 2 144 ? 162.195 131.680 101.727 1.00 211.12 ? 144 A   C N9    1 
ATOM   8665 C C8    . A   C 2 144 ? 161.080 132.479 101.787 1.00 211.12 ? 144 A   C C8    1 
ATOM   8666 N N7    . A   C 2 144 ? 161.278 133.620 102.400 1.00 211.12 ? 144 A   C N7    1 
ATOM   8667 C C5    . A   C 2 144 ? 162.614 133.570 102.770 1.00 211.12 ? 144 A   C C5    1 
ATOM   8668 C C6    . A   C 2 144 ? 163.437 134.480 103.455 1.00 211.12 ? 144 A   C C6    1 
ATOM   8669 N N6    . A   C 2 144 ? 163.004 135.660 103.902 1.00 211.12 ? 144 A   C N6    1 
ATOM   8670 N N1    . A   C 2 144 ? 164.727 134.135 103.670 1.00 211.12 ? 144 A   C N1    1 
ATOM   8671 C C2    . A   C 2 144 ? 165.146 132.947 103.212 1.00 211.12 ? 144 A   C C2    1 
ATOM   8672 N N3    . A   C 2 144 ? 164.470 132.006 102.555 1.00 211.12 ? 144 A   C N3    1 
ATOM   8673 C C4    . A   C 2 144 ? 163.193 132.382 102.362 1.00 211.12 ? 144 A   C C4    1 
ATOM   8674 P P     . C   C 2 145 ? 160.184 127.256 104.170 1.00 207.63 ? 145 C   C P     1 
ATOM   8675 O OP1   . C   C 2 145 ? 159.676 125.865 104.285 1.00 207.63 ? 145 C   C OP1   1 
ATOM   8676 O OP2   . C   C 2 145 ? 159.313 128.391 104.567 1.00 207.63 ? 145 C   C OP2   1 
ATOM   8677 O "O5'" . C   C 2 145 ? 161.537 127.355 105.002 1.00 207.63 ? 145 C   C "O5'" 1 
ATOM   8678 C "C5'" . C   C 2 145 ? 162.679 126.607 104.616 1.00 207.63 ? 145 C   C "C5'" 1 
ATOM   8679 C "C4'" . C   C 2 145 ? 163.937 127.166 105.229 1.00 207.63 ? 145 C   C "C4'" 1 
ATOM   8680 O "O4'" . C   C 2 145 ? 164.200 128.492 104.701 1.00 207.63 ? 145 C   C "O4'" 1 
ATOM   8681 C "C3'" . C   C 2 145 ? 163.902 127.373 106.733 1.00 207.63 ? 145 C   C "C3'" 1 
ATOM   8682 O "O3'" . C   C 2 145 ? 164.118 126.176 107.457 1.00 207.63 ? 145 C   C "O3'" 1 
ATOM   8683 C "C2'" . C   C 2 145 ? 164.978 128.429 106.945 1.00 207.63 ? 145 C   C "C2'" 1 
ATOM   8684 O "O2'" . C   C 2 145 ? 166.271 127.844 106.898 1.00 207.63 ? 145 C   C "O2'" 1 
ATOM   8685 C "C1'" . C   C 2 145 ? 164.794 129.297 105.698 1.00 207.63 ? 145 C   C "C1'" 1 
ATOM   8686 N N1    . C   C 2 145 ? 163.916 130.461 105.956 1.00 207.63 ? 145 C   C N1    1 
ATOM   8687 C C2    . C   C 2 145 ? 164.465 131.585 106.578 1.00 207.63 ? 145 C   C C2    1 
ATOM   8688 O O2    . C   C 2 145 ? 165.661 131.575 106.898 1.00 207.63 ? 145 C   C O2    1 
ATOM   8689 N N3    . C   C 2 145 ? 163.686 132.660 106.830 1.00 207.63 ? 145 C   C N3    1 
ATOM   8690 C C4    . C   C 2 145 ? 162.401 132.643 106.475 1.00 207.63 ? 145 C   C C4    1 
ATOM   8691 N N4    . C   C 2 145 ? 161.673 133.729 106.744 1.00 207.63 ? 145 C   C N4    1 
ATOM   8692 C C5    . C   C 2 145 ? 161.809 131.514 105.838 1.00 207.63 ? 145 C   C C5    1 
ATOM   8693 C C6    . C   C 2 145 ? 162.595 130.456 105.598 1.00 207.63 ? 145 C   C C6    1 
ATOM   8694 P P     . A   C 2 146 ? 162.892 125.461 108.207 1.00 197.07 ? 146 A   C P     1 
ATOM   8695 O OP1   . A   C 2 146 ? 162.907 124.018 107.855 1.00 197.07 ? 146 A   C OP1   1 
ATOM   8696 O OP2   . A   C 2 146 ? 161.670 126.267 107.956 1.00 197.07 ? 146 A   C OP2   1 
ATOM   8697 O "O5'" . A   C 2 146 ? 163.259 125.601 109.748 1.00 197.07 ? 146 A   C "O5'" 1 
ATOM   8698 C "C5'" . A   C 2 146 ? 164.569 125.309 110.209 1.00 197.07 ? 146 A   C "C5'" 1 
ATOM   8699 C "C4'" . A   C 2 146 ? 165.002 126.286 111.269 1.00 197.07 ? 146 A   C "C4'" 1 
ATOM   8700 O "O4'" . A   C 2 146 ? 165.324 127.564 110.663 1.00 197.07 ? 146 A   C "O4'" 1 
ATOM   8701 C "C3'" . A   C 2 146 ? 163.955 126.629 112.314 1.00 197.07 ? 146 A   C "C3'" 1 
ATOM   8702 O "O3'" . A   C 2 146 ? 163.847 125.645 113.326 1.00 197.07 ? 146 A   C "O3'" 1 
ATOM   8703 C "C2'" . A   C 2 146 ? 164.423 127.987 112.821 1.00 197.07 ? 146 A   C "C2'" 1 
ATOM   8704 O "O2'" . A   C 2 146 ? 165.491 127.836 113.745 1.00 197.07 ? 146 A   C "O2'" 1 
ATOM   8705 C "C1'" . A   C 2 146 ? 164.977 128.614 111.542 1.00 197.07 ? 146 A   C "C1'" 1 
ATOM   8706 N N9    . A   C 2 146 ? 163.999 129.492 110.873 1.00 197.07 ? 146 A   C N9    1 
ATOM   8707 C C8    . A   C 2 146 ? 163.218 129.212 109.779 1.00 197.07 ? 146 A   C C8    1 
ATOM   8708 N N7    . A   C 2 146 ? 162.449 130.207 109.409 1.00 197.07 ? 146 A   C N7    1 
ATOM   8709 C C5    . A   C 2 146 ? 162.744 131.211 110.321 1.00 197.07 ? 146 A   C C5    1 
ATOM   8710 C C6    . A   C 2 146 ? 162.263 132.523 110.475 1.00 197.07 ? 146 A   C C6    1 
ATOM   8711 N N6    . A   C 2 146 ? 161.344 133.075 109.680 1.00 197.07 ? 146 A   C N6    1 
ATOM   8712 N N1    . A   C 2 146 ? 162.763 133.262 111.489 1.00 197.07 ? 146 A   C N1    1 
ATOM   8713 C C2    . A   C 2 146 ? 163.687 132.711 112.286 1.00 197.07 ? 146 A   C C2    1 
ATOM   8714 N N3    . A   C 2 146 ? 164.217 131.492 112.244 1.00 197.07 ? 146 A   C N3    1 
ATOM   8715 C C4    . A   C 2 146 ? 163.697 130.784 111.227 1.00 197.07 ? 146 A   C C4    1 
ATOM   8716 P P     . C   C 2 147 ? 162.431 125.366 114.028 1.00 183.13 ? 147 C   C P     1 
ATOM   8717 O OP1   . C   C 2 147 ? 162.530 124.085 114.774 1.00 183.13 ? 147 C   C OP1   1 
ATOM   8718 O OP2   . C   C 2 147 ? 161.368 125.543 113.006 1.00 183.13 ? 147 C   C OP2   1 
ATOM   8719 O "O5'" . C   C 2 147 ? 162.298 126.544 115.089 1.00 183.13 ? 147 C   C "O5'" 1 
ATOM   8720 C "C5'" . C   C 2 147 ? 163.356 126.822 115.993 1.00 183.13 ? 147 C   C "C5'" 1 
ATOM   8721 C "C4'" . C   C 2 147 ? 163.207 128.186 116.617 1.00 183.13 ? 147 C   C "C4'" 1 
ATOM   8722 O "O4'" . C   C 2 147 ? 163.355 129.220 115.611 1.00 183.13 ? 147 C   C "O4'" 1 
ATOM   8723 C "C3'" . C   C 2 147 ? 161.859 128.482 117.246 1.00 183.13 ? 147 C   C "C3'" 1 
ATOM   8724 O "O3'" . C   C 2 147 ? 161.711 127.893 118.524 1.00 183.13 ? 147 C   C "O3'" 1 
ATOM   8725 C "C2'" . C   C 2 147 ? 161.828 130.005 117.257 1.00 183.13 ? 147 C   C "C2'" 1 
ATOM   8726 O "O2'" . C   C 2 147 ? 162.600 130.515 118.335 1.00 183.13 ? 147 C   C "O2'" 1 
ATOM   8727 C "C1'" . C   C 2 147 ? 162.551 130.333 115.948 1.00 183.13 ? 147 C   C "C1'" 1 
ATOM   8728 N N1    . C   C 2 147 ? 161.608 130.606 114.838 1.00 183.13 ? 147 C   C N1    1 
ATOM   8729 C C2    . C   C 2 147 ? 161.072 131.892 114.735 1.00 183.13 ? 147 C   C C2    1 
ATOM   8730 O O2    . C   C 2 147 ? 161.407 132.745 115.568 1.00 183.13 ? 147 C   C O2    1 
ATOM   8731 N N3    . C   C 2 147 ? 160.206 132.181 113.737 1.00 183.13 ? 147 C   C N3    1 
ATOM   8732 C C4    . C   C 2 147 ? 159.871 131.235 112.859 1.00 183.13 ? 147 C   C C4    1 
ATOM   8733 N N4    . C   C 2 147 ? 159.013 131.562 111.890 1.00 183.13 ? 147 C   C N4    1 
ATOM   8734 C C5    . C   C 2 147 ? 160.400 129.913 112.938 1.00 183.13 ? 147 C   C C5    1 
ATOM   8735 C C6    . C   C 2 147 ? 161.257 129.643 113.932 1.00 183.13 ? 147 C   C C6    1 
ATOM   8736 P P     . U   C 2 148 ? 160.323 127.199 118.932 1.00 170.07 ? 148 U   C P     1 
ATOM   8737 O OP1   . U   C 2 148 ? 160.592 126.236 120.030 1.00 170.07 ? 148 U   C OP1   1 
ATOM   8738 O OP2   . U   C 2 148 ? 159.660 126.729 117.689 1.00 170.07 ? 148 U   C OP2   1 
ATOM   8739 O "O5'" . U   C 2 148 ? 159.466 128.402 119.523 1.00 170.07 ? 148 U   C "O5'" 1 
ATOM   8740 C "C5'" . U   C 2 148 ? 160.044 129.313 120.445 1.00 170.07 ? 148 U   C "C5'" 1 
ATOM   8741 C "C4'" . U   C 2 148 ? 159.181 130.534 120.627 1.00 170.07 ? 148 U   C "C4'" 1 
ATOM   8742 O "O4'" . U   C 2 148 ? 159.274 131.390 119.460 1.00 170.07 ? 148 U   C "O4'" 1 
ATOM   8743 C "C3'" . U   C 2 148 ? 157.693 130.276 120.775 1.00 170.07 ? 148 U   C "C3'" 1 
ATOM   8744 O "O3'" . U   C 2 148 ? 157.337 129.869 122.084 1.00 170.07 ? 148 U   C "O3'" 1 
ATOM   8745 C "C2'" . U   C 2 148 ? 157.080 131.606 120.355 1.00 170.07 ? 148 U   C "C2'" 1 
ATOM   8746 O "O2'" . U   C 2 148 ? 157.144 132.547 121.417 1.00 170.07 ? 148 U   C "O2'" 1 
ATOM   8747 C "C1'" . U   C 2 148 ? 158.045 132.053 119.252 1.00 170.07 ? 148 U   C "C1'" 1 
ATOM   8748 N N1    . U   C 2 148 ? 157.546 131.728 117.896 1.00 170.07 ? 148 U   C N1    1 
ATOM   8749 C C2    . U   C 2 148 ? 156.631 132.597 117.335 1.00 170.07 ? 148 U   C C2    1 
ATOM   8750 O O2    . U   C 2 148 ? 156.231 133.594 117.911 1.00 170.07 ? 148 U   C O2    1 
ATOM   8751 N N3    . U   C 2 148 ? 156.196 132.262 116.076 1.00 170.07 ? 148 U   C N3    1 
ATOM   8752 C C4    . U   C 2 148 ? 156.580 131.162 115.336 1.00 170.07 ? 148 U   C C4    1 
ATOM   8753 O O4    . U   C 2 148 ? 156.104 130.986 114.213 1.00 170.07 ? 148 U   C O4    1 
ATOM   8754 C C5    . U   C 2 148 ? 157.532 130.311 115.984 1.00 170.07 ? 148 U   C C5    1 
ATOM   8755 C C6    . U   C 2 148 ? 157.973 130.615 117.210 1.00 170.07 ? 148 U   C C6    1 
ATOM   8756 P P     . G   C 2 149 ? 155.969 129.068 122.336 1.00 160.02 ? 149 G   C P     1 
ATOM   8757 O OP1   . G   C 2 149 ? 156.145 128.211 123.536 1.00 160.02 ? 149 G   C OP1   1 
ATOM   8758 O OP2   . G   C 2 149 ? 155.552 128.453 121.050 1.00 160.02 ? 149 G   C OP2   1 
ATOM   8759 O "O5'" . G   C 2 149 ? 154.924 130.214 122.692 1.00 160.02 ? 149 G   C "O5'" 1 
ATOM   8760 C "C5'" . G   C 2 149 ? 153.535 130.019 122.487 1.00 160.02 ? 149 G   C "C5'" 1 
ATOM   8761 C "C4'" . G   C 2 149 ? 152.850 131.307 122.111 1.00 160.02 ? 149 G   C "C4'" 1 
ATOM   8762 O "O4'" . G   C 2 149 ? 153.634 132.009 121.112 1.00 160.02 ? 149 G   C "O4'" 1 
ATOM   8763 C "C3'" . G   C 2 149 ? 151.479 131.159 121.474 1.00 160.02 ? 149 G   C "C3'" 1 
ATOM   8764 O "O3'" . G   C 2 149 ? 150.455 130.972 122.433 1.00 160.02 ? 149 G   C "O3'" 1 
ATOM   8765 C "C2'" . G   C 2 149 ? 151.340 132.444 120.669 1.00 160.02 ? 149 G   C "C2'" 1 
ATOM   8766 O "O2'" . G   C 2 149 ? 150.973 133.526 121.512 1.00 160.02 ? 149 G   C "O2'" 1 
ATOM   8767 C "C1'" . G   C 2 149 ? 152.779 132.665 120.200 1.00 160.02 ? 149 G   C "C1'" 1 
ATOM   8768 N N9    . G   C 2 149 ? 153.026 132.110 118.855 1.00 160.02 ? 149 G   C N9    1 
ATOM   8769 C C8    . G   C 2 149 ? 153.885 131.083 118.546 1.00 160.02 ? 149 G   C C8    1 
ATOM   8770 N N7    . G   C 2 149 ? 153.913 130.801 117.274 1.00 160.02 ? 149 G   C N7    1 
ATOM   8771 C C5    . G   C 2 149 ? 153.022 131.699 116.707 1.00 160.02 ? 149 G   C C5    1 
ATOM   8772 C C6    . G   C 2 149 ? 152.637 131.869 115.355 1.00 160.02 ? 149 G   C C6    1 
ATOM   8773 O O6    . G   C 2 149 ? 153.024 131.237 114.366 1.00 160.02 ? 149 G   C O6    1 
ATOM   8774 N N1    . G   C 2 149 ? 151.708 132.894 115.210 1.00 160.02 ? 149 G   C N1    1 
ATOM   8775 C C2    . G   C 2 149 ? 151.210 133.658 116.237 1.00 160.02 ? 149 G   C C2    1 
ATOM   8776 N N2    . G   C 2 149 ? 150.320 134.605 115.910 1.00 160.02 ? 149 G   C N2    1 
ATOM   8777 N N3    . G   C 2 149 ? 151.564 133.508 117.504 1.00 160.02 ? 149 G   C N3    1 
ATOM   8778 C C4    . G   C 2 149 ? 152.467 132.518 117.666 1.00 160.02 ? 149 G   C C4    1 
ATOM   8779 P P     . U   C 2 150 ? 149.421 129.752 122.286 1.00 154.14 ? 150 U   C P     1 
ATOM   8780 O OP1   . U   C 2 150 ? 148.927 129.397 123.641 1.00 154.14 ? 150 U   C OP1   1 
ATOM   8781 O OP2   . U   C 2 150 ? 150.053 128.710 121.439 1.00 154.14 ? 150 U   C OP2   1 
ATOM   8782 O "O5'" . U   C 2 150 ? 148.210 130.385 121.470 1.00 154.14 ? 150 U   C "O5'" 1 
ATOM   8783 C "C5'" . U   C 2 150 ? 147.711 131.672 121.797 1.00 154.14 ? 150 U   C "C5'" 1 
ATOM   8784 C "C4'" . U   C 2 150 ? 147.004 132.297 120.624 1.00 154.14 ? 150 U   C "C4'" 1 
ATOM   8785 O "O4'" . U   C 2 150 ? 147.964 132.619 119.585 1.00 154.14 ? 150 U   C "O4'" 1 
ATOM   8786 C "C3'" . U   C 2 150 ? 145.984 131.412 119.926 1.00 154.14 ? 150 U   C "C3'" 1 
ATOM   8787 O "O3'" . U   C 2 150 ? 144.735 131.390 120.593 1.00 154.14 ? 150 U   C "O3'" 1 
ATOM   8788 C "C2'" . U   C 2 150 ? 145.923 132.011 118.527 1.00 154.14 ? 150 U   C "C2'" 1 
ATOM   8789 O "O2'" . U   C 2 150 ? 145.109 133.174 118.513 1.00 154.14 ? 150 U   C "O2'" 1 
ATOM   8790 C "C1'" . U   C 2 150 ? 147.378 132.437 118.314 1.00 154.14 ? 150 U   C "C1'" 1 
ATOM   8791 N N1    . U   C 2 150 ? 148.162 131.423 117.571 1.00 154.14 ? 150 U   C N1    1 
ATOM   8792 C C2    . U   C 2 150 ? 147.992 131.350 116.202 1.00 154.14 ? 150 U   C C2    1 
ATOM   8793 O O2    . U   C 2 150 ? 147.227 132.075 115.590 1.00 154.14 ? 150 U   C O2    1 
ATOM   8794 N N3    . U   C 2 150 ? 148.747 130.396 115.569 1.00 154.14 ? 150 U   C N3    1 
ATOM   8795 C C4    . U   C 2 150 ? 149.642 129.526 116.155 1.00 154.14 ? 150 U   C C4    1 
ATOM   8796 O O4    . U   C 2 150 ? 150.254 128.717 115.455 1.00 154.14 ? 150 U   C O4    1 
ATOM   8797 C C5    . U   C 2 150 ? 149.765 129.665 117.573 1.00 154.14 ? 150 U   C C5    1 
ATOM   8798 C C6    . U   C 2 150 ? 149.041 130.586 118.216 1.00 154.14 ? 150 U   C C6    1 
ATOM   8799 P P     . A   C 2 151 ? 143.978 129.996 120.852 1.00 156.97 ? 151 A   C P     1 
ATOM   8800 O OP1   . A   C 2 151 ? 143.072 130.173 122.015 1.00 156.97 ? 151 A   C OP1   1 
ATOM   8801 O OP2   . A   C 2 151 ? 144.995 128.914 120.870 1.00 156.97 ? 151 A   C OP2   1 
ATOM   8802 O "O5'" . A   C 2 151 ? 143.081 129.806 119.551 1.00 156.97 ? 151 A   C "O5'" 1 
ATOM   8803 C "C5'" . A   C 2 151 ? 142.311 130.887 119.037 1.00 156.97 ? 151 A   C "C5'" 1 
ATOM   8804 C "C4'" . A   C 2 151 ? 142.046 130.733 117.560 1.00 156.97 ? 151 A   C "C4'" 1 
ATOM   8805 O "O4'" . A   C 2 151 ? 143.312 130.594 116.856 1.00 156.97 ? 151 A   C "O4'" 1 
ATOM   8806 C "C3'" . A   C 2 151 ? 141.207 129.517 117.169 1.00 156.97 ? 151 A   C "C3'" 1 
ATOM   8807 O "O3'" . A   C 2 151 ? 140.409 129.842 116.031 1.00 156.97 ? 151 A   C "O3'" 1 
ATOM   8808 C "C2'" . A   C 2 151 ? 142.267 128.499 116.761 1.00 156.97 ? 151 A   C "C2'" 1 
ATOM   8809 O "O2'" . A   C 2 151 ? 141.809 127.493 115.883 1.00 156.97 ? 151 A   C "O2'" 1 
ATOM   8810 C "C1'" . A   C 2 151 ? 143.302 129.400 116.098 1.00 156.97 ? 151 A   C "C1'" 1 
ATOM   8811 N N9    . A   C 2 151 ? 144.657 128.846 116.063 1.00 156.97 ? 151 A   C N9    1 
ATOM   8812 C C8    . A   C 2 151 ? 145.546 128.640 117.089 1.00 156.97 ? 151 A   C C8    1 
ATOM   8813 N N7    . A   C 2 151 ? 146.688 128.124 116.696 1.00 156.97 ? 151 A   C N7    1 
ATOM   8814 C C5    . A   C 2 151 ? 146.540 127.984 115.322 1.00 156.97 ? 151 A   C C5    1 
ATOM   8815 C C6    . A   C 2 151 ? 147.388 127.496 114.310 1.00 156.97 ? 151 A   C C6    1 
ATOM   8816 N N6    . A   C 2 151 ? 148.619 127.032 114.534 1.00 156.97 ? 151 A   C N6    1 
ATOM   8817 N N1    . A   C 2 151 ? 146.920 127.499 113.040 1.00 156.97 ? 151 A   C N1    1 
ATOM   8818 C C2    . A   C 2 151 ? 145.686 127.966 112.819 1.00 156.97 ? 151 A   C C2    1 
ATOM   8819 N N3    . A   C 2 151 ? 144.797 128.447 113.679 1.00 156.97 ? 151 A   C N3    1 
ATOM   8820 C C4    . A   C 2 151 ? 145.295 128.430 114.925 1.00 156.97 ? 151 A   C C4    1 
ATOM   8821 P P     . A   C 2 152 ? 138.870 129.388 115.964 1.00 180.40 ? 152 A   C P     1 
ATOM   8822 O OP1   . A   C 2 152 ? 138.832 127.905 115.896 1.00 180.40 ? 152 A   C OP1   1 
ATOM   8823 O OP2   . A   C 2 152 ? 138.201 130.190 114.909 1.00 180.40 ? 152 A   C OP2   1 
ATOM   8824 O "O5'" . A   C 2 152 ? 138.275 129.829 117.373 1.00 180.40 ? 152 A   C "O5'" 1 
ATOM   8825 C "C5'" . A   C 2 152 ? 136.873 129.898 117.580 1.00 180.40 ? 152 A   C "C5'" 1 
ATOM   8826 C "C4'" . A   C 2 152 ? 136.511 129.571 119.006 1.00 180.40 ? 152 A   C "C4'" 1 
ATOM   8827 O "O4'" . A   C 2 152 ? 136.907 128.207 119.311 1.00 180.40 ? 152 A   C "O4'" 1 
ATOM   8828 C "C3'" . A   C 2 152 ? 137.200 130.404 120.076 1.00 180.40 ? 152 A   C "C3'" 1 
ATOM   8829 O "O3'" . A   C 2 152 ? 136.587 131.669 120.273 1.00 180.40 ? 152 A   C "O3'" 1 
ATOM   8830 C "C2'" . A   C 2 152 ? 137.143 129.491 121.292 1.00 180.40 ? 152 A   C "C2'" 1 
ATOM   8831 O "O2'" . A   C 2 152 ? 135.848 129.511 121.874 1.00 180.40 ? 152 A   C "O2'" 1 
ATOM   8832 C "C1'" . A   C 2 152 ? 137.361 128.124 120.646 1.00 180.40 ? 152 A   C "C1'" 1 
ATOM   8833 N N9    . A   C 2 152 ? 138.788 127.747 120.625 1.00 180.40 ? 152 A   C N9    1 
ATOM   8834 C C8    . A   C 2 152 ? 139.568 127.509 119.521 1.00 180.40 ? 152 A   C C8    1 
ATOM   8835 N N7    . A   C 2 152 ? 140.807 127.191 119.806 1.00 180.40 ? 152 A   C N7    1 
ATOM   8836 C C5    . A   C 2 152 ? 140.846 127.219 121.194 1.00 180.40 ? 152 A   C C5    1 
ATOM   8837 C C6    . A   C 2 152 ? 141.879 126.972 122.115 1.00 180.40 ? 152 A   C C6    1 
ATOM   8838 N N6    . A   C 2 152 ? 143.122 126.635 121.763 1.00 180.40 ? 152 A   C N6    1 
ATOM   8839 N N1    . A   C 2 152 ? 141.589 127.085 123.430 1.00 180.40 ? 152 A   C N1    1 
ATOM   8840 C C2    . A   C 2 152 ? 140.343 127.424 123.784 1.00 180.40 ? 152 A   C C2    1 
ATOM   8841 N N3    . A   C 2 152 ? 139.289 127.680 123.013 1.00 180.40 ? 152 A   C N3    1 
ATOM   8842 C C4    . A   C 2 152 ? 139.609 127.559 121.712 1.00 180.40 ? 152 A   C C4    1 
ATOM   8843 P P     . A   C 2 153 ? 137.207 132.755 121.291 1.00 193.88 ? 153 A   C P     1 
ATOM   8844 O OP1   . A   C 2 153 ? 137.050 132.255 122.678 1.00 193.88 ? 153 A   C OP1   1 
ATOM   8845 O OP2   . A   C 2 153 ? 136.621 134.069 120.927 1.00 193.88 ? 153 A   C OP2   1 
ATOM   8846 O "O5'" . A   C 2 153 ? 138.765 132.808 120.952 1.00 193.88 ? 153 A   C "O5'" 1 
ATOM   8847 C "C5'" . A   C 2 153 ? 139.715 132.089 121.729 1.00 193.88 ? 153 A   C "C5'" 1 
ATOM   8848 C "C4'" . A   C 2 153 ? 140.454 132.981 122.697 1.00 193.88 ? 153 A   C "C4'" 1 
ATOM   8849 O "O4'" . A   C 2 153 ? 140.716 134.273 122.088 1.00 193.88 ? 153 A   C "O4'" 1 
ATOM   8850 C "C3'" . A   C 2 153 ? 139.726 133.329 123.986 1.00 193.88 ? 153 A   C "C3'" 1 
ATOM   8851 O "O3'" . A   C 2 153 ? 139.774 132.296 124.956 1.00 193.88 ? 153 A   C "O3'" 1 
ATOM   8852 C "C2'" . A   C 2 153 ? 140.432 134.605 124.423 1.00 193.88 ? 153 A   C "C2'" 1 
ATOM   8853 O "O2'" . A   C 2 153 ? 141.689 134.307 125.014 1.00 193.88 ? 153 A   C "O2'" 1 
ATOM   8854 C "C1'" . A   C 2 153 ? 140.681 135.284 123.076 1.00 193.88 ? 153 A   C "C1'" 1 
ATOM   8855 N N9    . A   C 2 153 ? 139.608 136.239 122.745 1.00 193.88 ? 153 A   C N9    1 
ATOM   8856 C C8    . A   C 2 153 ? 138.667 136.149 121.749 1.00 193.88 ? 153 A   C C8    1 
ATOM   8857 N N7    . A   C 2 153 ? 137.837 137.163 121.715 1.00 193.88 ? 153 A   C N7    1 
ATOM   8858 C C5    . A   C 2 153 ? 138.258 137.976 122.759 1.00 193.88 ? 153 A   C C5    1 
ATOM   8859 C C6    . A   C 2 153 ? 137.791 139.208 123.250 1.00 193.88 ? 153 A   C C6    1 
ATOM   8860 N N6    . A   C 2 153 ? 136.751 139.866 122.733 1.00 193.88 ? 153 A   C N6    1 
ATOM   8861 N N1    . A   C 2 153 ? 138.436 139.750 124.306 1.00 193.88 ? 153 A   C N1    1 
ATOM   8862 C C2    . A   C 2 153 ? 139.478 139.092 124.827 1.00 193.88 ? 153 A   C C2    1 
ATOM   8863 N N3    . A   C 2 153 ? 140.010 137.930 124.454 1.00 193.88 ? 153 A   C N3    1 
ATOM   8864 C C4    . A   C 2 153 ? 139.347 137.418 123.402 1.00 193.88 ? 153 A   C C4    1 
ATOM   8865 P P     . U   C 2 154 ? 138.425 131.750 125.645 1.00 206.97 ? 154 U   C P     1 
ATOM   8866 O OP1   . U   C 2 154 ? 138.741 131.438 127.062 1.00 206.97 ? 154 U   C OP1   1 
ATOM   8867 O OP2   . U   C 2 154 ? 137.859 130.685 124.780 1.00 206.97 ? 154 U   C OP2   1 
ATOM   8868 O "O5'" . U   C 2 154 ? 137.431 132.997 125.636 1.00 206.97 ? 154 U   C "O5'" 1 
ATOM   8869 C "C5'" . U   C 2 154 ? 137.535 134.019 126.619 1.00 206.97 ? 154 U   C "C5'" 1 
ATOM   8870 C "C4'" . U   C 2 154 ? 136.272 134.839 126.726 1.00 206.97 ? 154 U   C "C4'" 1 
ATOM   8871 O "O4'" . U   C 2 154 ? 135.882 135.342 125.424 1.00 206.97 ? 154 U   C "O4'" 1 
ATOM   8872 C "C3'" . U   C 2 154 ? 135.031 134.113 127.218 1.00 206.97 ? 154 U   C "C3'" 1 
ATOM   8873 O "O3'" . U   C 2 154 ? 135.018 133.933 128.622 1.00 206.97 ? 154 U   C "O3'" 1 
ATOM   8874 C "C2'" . U   C 2 154 ? 133.906 135.007 126.709 1.00 206.97 ? 154 U   C "C2'" 1 
ATOM   8875 O "O2'" . U   C 2 154 ? 133.741 136.137 127.553 1.00 206.97 ? 154 U   C "O2'" 1 
ATOM   8876 C "C1'" . U   C 2 154 ? 134.476 135.484 125.369 1.00 206.97 ? 154 U   C "C1'" 1 
ATOM   8877 N N1    . U   C 2 154 ? 133.944 134.707 124.226 1.00 206.97 ? 154 U   C N1    1 
ATOM   8878 C C2    . U   C 2 154 ? 132.835 135.222 123.583 1.00 206.97 ? 154 U   C C2    1 
ATOM   8879 O O2    . U   C 2 154 ? 132.309 136.270 123.917 1.00 206.97 ? 154 U   C O2    1 
ATOM   8880 N N3    . U   C 2 154 ? 132.367 134.473 122.532 1.00 206.97 ? 154 U   C N3    1 
ATOM   8881 C C4    . U   C 2 154 ? 132.881 133.281 122.070 1.00 206.97 ? 154 U   C C4    1 
ATOM   8882 O O4    . U   C 2 154 ? 132.349 132.721 121.110 1.00 206.97 ? 154 U   C O4    1 
ATOM   8883 C C5    . U   C 2 154 ? 134.024 132.809 122.790 1.00 206.97 ? 154 U   C C5    1 
ATOM   8884 C C6    . U   C 2 154 ? 134.503 133.519 123.818 1.00 206.97 ? 154 U   C C6    1 
ATOM   8885 P P     . C   C 2 155 ? 134.973 132.453 129.247 1.00 181.45 ? 155 C   C P     1 
ATOM   8886 O OP1   . C   C 2 155 ? 136.362 132.052 129.584 1.00 181.45 ? 155 C   C OP1   1 
ATOM   8887 O OP2   . C   C 2 155 ? 134.159 131.598 128.346 1.00 181.45 ? 155 C   C OP2   1 
ATOM   8888 O "O5'" . C   C 2 155 ? 134.169 132.638 130.609 1.00 181.45 ? 155 C   C "O5'" 1 
ATOM   8889 C "C5'" . C   C 2 155 ? 132.774 132.923 130.601 1.00 181.45 ? 155 C   C "C5'" 1 
ATOM   8890 C "C4'" . C   C 2 155 ? 132.281 133.337 131.965 1.00 181.45 ? 155 C   C "C4'" 1 
ATOM   8891 O "O4'" . C   C 2 155 ? 132.857 134.628 132.308 1.00 181.45 ? 155 C   C "O4'" 1 
ATOM   8892 C "C3'" . C   C 2 155 ? 130.768 133.500 132.089 1.00 181.45 ? 155 C   C "C3'" 1 
ATOM   8893 O "O3'" . C   C 2 155 ? 130.360 133.133 133.406 1.00 181.45 ? 155 C   C "O3'" 1 
ATOM   8894 C "C2'" . C   C 2 155 ? 130.578 135.001 131.903 1.00 181.45 ? 155 C   C "C2'" 1 
ATOM   8895 O "O2'" . C   C 2 155 ? 129.393 135.519 132.471 1.00 181.45 ? 155 C   C "O2'" 1 
ATOM   8896 C "C1'" . C   C 2 155 ? 131.824 135.551 132.590 1.00 181.45 ? 155 C   C "C1'" 1 
ATOM   8897 N N1    . C   C 2 155 ? 132.243 136.874 132.106 1.00 181.45 ? 155 C   C N1    1 
ATOM   8898 C C2    . C   C 2 155 ? 132.419 137.904 133.035 1.00 181.45 ? 155 C   C C2    1 
ATOM   8899 O O2    . C   C 2 155 ? 132.219 137.667 134.235 1.00 181.45 ? 155 C   C O2    1 
ATOM   8900 N N3    . C   C 2 155 ? 132.804 139.126 132.603 1.00 181.45 ? 155 C   C N3    1 
ATOM   8901 C C4    . C   C 2 155 ? 133.010 139.339 131.303 1.00 181.45 ? 155 C   C C4    1 
ATOM   8902 N N4    . C   C 2 155 ? 133.389 140.561 130.922 1.00 181.45 ? 155 C   C N4    1 
ATOM   8903 C C5    . C   C 2 155 ? 132.837 138.308 130.334 1.00 181.45 ? 155 C   C C5    1 
ATOM   8904 C C6    . C   C 2 155 ? 132.456 137.102 130.775 1.00 181.45 ? 155 C   C C6    1 
ATOM   8905 P P     . U   C 2 156 ? 130.010 131.603 133.759 1.00 142.01 ? 156 U   C P     1 
ATOM   8906 O OP1   . U   C 2 156 ? 130.949 130.708 133.036 1.00 142.01 ? 156 U   C OP1   1 
ATOM   8907 O OP2   . U   C 2 156 ? 128.548 131.421 133.582 1.00 142.01 ? 156 U   C OP2   1 
ATOM   8908 O "O5'" . U   C 2 156 ? 130.331 131.494 135.314 1.00 142.01 ? 156 U   C "O5'" 1 
ATOM   8909 C "C5'" . U   C 2 156 ? 129.557 132.210 136.270 1.00 142.01 ? 156 U   C "C5'" 1 
ATOM   8910 C "C4'" . U   C 2 156 ? 130.355 133.301 136.942 1.00 142.01 ? 156 U   C "C4'" 1 
ATOM   8911 O "O4'" . U   C 2 156 ? 129.531 133.914 137.971 1.00 142.01 ? 156 U   C "O4'" 1 
ATOM   8912 C "C3'" . U   C 2 156 ? 131.629 132.835 137.641 1.00 142.01 ? 156 U   C "C3'" 1 
ATOM   8913 O "O3'" . U   C 2 156 ? 132.618 133.863 137.579 1.00 142.01 ? 156 U   C "O3'" 1 
ATOM   8914 C "C2'" . U   C 2 156 ? 131.171 132.651 139.083 1.00 142.01 ? 156 U   C "C2'" 1 
ATOM   8915 O "O2'" . U   C 2 156 ? 132.204 132.743 140.042 1.00 142.01 ? 156 U   C "O2'" 1 
ATOM   8916 C "C1'" . U   C 2 156 ? 130.158 133.783 139.233 1.00 142.01 ? 156 U   C "C1'" 1 
ATOM   8917 N N1    . U   C 2 156 ? 129.114 133.511 140.231 1.00 142.01 ? 156 U   C N1    1 
ATOM   8918 C C2    . U   C 2 156 ? 129.048 134.328 141.342 1.00 142.01 ? 156 U   C C2    1 
ATOM   8919 O O2    . U   C 2 156 ? 129.811 135.260 141.524 1.00 142.01 ? 156 U   C O2    1 
ATOM   8920 N N3    . U   C 2 156 ? 128.051 134.015 142.233 1.00 142.01 ? 156 U   C N3    1 
ATOM   8921 C C4    . U   C 2 156 ? 127.135 132.990 142.129 1.00 142.01 ? 156 U   C C4    1 
ATOM   8922 O O4    . U   C 2 156 ? 126.295 132.835 143.016 1.00 142.01 ? 156 U   C O4    1 
ATOM   8923 C C5    . U   C 2 156 ? 127.271 132.188 140.951 1.00 142.01 ? 156 U   C C5    1 
ATOM   8924 C C6    . U   C 2 156 ? 128.232 132.470 140.066 1.00 142.01 ? 156 U   C C6    1 
ATOM   8925 P P     . C   C 2 157 ? 134.187 133.517 137.457 1.00 155.56 ? 157 C   C P     1 
ATOM   8926 O OP1   . C   C 2 157 ? 134.427 132.887 136.132 1.00 155.56 ? 157 C   C OP1   1 
ATOM   8927 O OP2   . C   C 2 157 ? 134.620 132.820 138.697 1.00 155.56 ? 157 C   C OP2   1 
ATOM   8928 O "O5'" . C   C 2 157 ? 134.859 134.961 137.456 1.00 155.56 ? 157 C   C "O5'" 1 
ATOM   8929 C "C5'" . C   C 2 157 ? 136.016 135.251 138.261 1.00 155.56 ? 157 C   C "C5'" 1 
ATOM   8930 C "C4'" . C   C 2 157 ? 136.773 136.430 137.689 1.00 155.56 ? 157 C   C "C4'" 1 
ATOM   8931 O "O4'" . C   C 2 157 ? 137.112 136.172 136.298 1.00 155.56 ? 157 C   C "O4'" 1 
ATOM   8932 C "C3'" . C   C 2 157 ? 136.044 137.776 137.711 1.00 155.56 ? 157 C   C "C3'" 1 
ATOM   8933 O "O3'" . C   C 2 157 ? 136.949 138.814 138.072 1.00 155.56 ? 157 C   C "O3'" 1 
ATOM   8934 C "C2'" . C   C 2 157 ? 135.656 137.987 136.249 1.00 155.56 ? 157 C   C "C2'" 1 
ATOM   8935 O "O2'" . C   C 2 157 ? 135.526 139.343 135.876 1.00 155.56 ? 157 C   C "O2'" 1 
ATOM   8936 C "C1'" . C   C 2 157 ? 136.836 137.328 135.540 1.00 155.56 ? 157 C   C "C1'" 1 
ATOM   8937 N N1    . C   C 2 157 ? 136.637 136.950 134.127 1.00 155.56 ? 157 C   C N1    1 
ATOM   8938 C C2    . C   C 2 157 ? 135.657 136.011 133.779 1.00 155.56 ? 157 C   C C2    1 
ATOM   8939 O O2    . C   C 2 157 ? 134.956 135.511 134.670 1.00 155.56 ? 157 C   C O2    1 
ATOM   8940 N N3    . C   C 2 157 ? 135.500 135.674 132.479 1.00 155.56 ? 157 C   C N3    1 
ATOM   8941 C C4    . C   C 2 157 ? 136.271 136.236 131.546 1.00 155.56 ? 157 C   C C4    1 
ATOM   8942 N N4    . C   C 2 157 ? 136.078 135.876 130.275 1.00 155.56 ? 157 C   C N4    1 
ATOM   8943 C C5    . C   C 2 157 ? 137.278 137.187 131.873 1.00 155.56 ? 157 C   C C5    1 
ATOM   8944 C C6    . C   C 2 157 ? 137.425 137.513 133.163 1.00 155.56 ? 157 C   C C6    1 
ATOM   8945 P P     . U   C 2 158 ? 137.261 139.134 139.610 1.00 116.43 ? 158 U   C P     1 
ATOM   8946 O OP1   . U   C 2 158 ? 137.212 140.605 139.789 1.00 116.43 ? 158 U   C OP1   1 
ATOM   8947 O OP2   . U   C 2 158 ? 138.485 138.391 139.998 1.00 116.43 ? 158 U   C OP2   1 
ATOM   8948 O "O5'" . U   C 2 158 ? 136.016 138.503 140.379 1.00 116.43 ? 158 U   C "O5'" 1 
ATOM   8949 C "C5'" . U   C 2 158 ? 136.213 137.555 141.445 1.00 116.43 ? 158 U   C "C5'" 1 
ATOM   8950 C "C4'" . U   C 2 158 ? 135.000 137.514 142.341 1.00 116.43 ? 158 U   C "C4'" 1 
ATOM   8951 O "O4'" . U   C 2 158 ? 133.934 138.317 141.759 1.00 116.43 ? 158 U   C "O4'" 1 
ATOM   8952 C "C3'" . U   C 2 158 ? 134.399 136.132 142.552 1.00 116.43 ? 158 U   C "C3'" 1 
ATOM   8953 O "O3'" . U   C 2 158 ? 133.781 136.122 143.831 1.00 116.43 ? 158 U   C "O3'" 1 
ATOM   8954 C "C2'" . U   C 2 158 ? 133.334 136.084 141.467 1.00 116.43 ? 158 U   C "C2'" 1 
ATOM   8955 O "O2'" . U   C 2 158 ? 132.333 135.121 141.705 1.00 116.43 ? 158 U   C "O2'" 1 
ATOM   8956 C "C1'" . U   C 2 158 ? 132.794 137.508 141.542 1.00 116.43 ? 158 U   C "C1'" 1 
ATOM   8957 N N1    . U   C 2 158 ? 132.128 137.966 140.317 1.00 116.43 ? 158 U   C N1    1 
ATOM   8958 C C2    . U   C 2 158 ? 130.924 138.627 140.455 1.00 116.43 ? 158 U   C C2    1 
ATOM   8959 O O2    . U   C 2 158 ? 130.405 138.838 141.537 1.00 116.43 ? 158 U   C O2    1 
ATOM   8960 N N3    . U   C 2 158 ? 130.352 139.034 139.276 1.00 116.43 ? 158 U   C N3    1 
ATOM   8961 C C4    . U   C 2 158 ? 130.845 138.853 138.002 1.00 116.43 ? 158 U   C C4    1 
ATOM   8962 O O4    . U   C 2 158 ? 130.208 139.278 137.038 1.00 116.43 ? 158 U   C O4    1 
ATOM   8963 C C5    . U   C 2 158 ? 132.095 138.159 137.943 1.00 116.43 ? 158 U   C C5    1 
ATOM   8964 C C6    . U   C 2 158 ? 132.678 137.749 139.075 1.00 116.43 ? 158 U   C C6    1 
ATOM   8965 P P     . A   C 2 159 ? 133.716 134.776 144.685 1.00 108.54 ? 159 A   C P     1 
ATOM   8966 O OP1   . A   C 2 159 ? 134.733 134.864 145.763 1.00 108.54 ? 159 A   C OP1   1 
ATOM   8967 O OP2   . A   C 2 159 ? 133.738 133.629 143.745 1.00 108.54 ? 159 A   C OP2   1 
ATOM   8968 O "O5'" . A   C 2 159 ? 132.272 134.847 145.351 1.00 108.54 ? 159 A   C "O5'" 1 
ATOM   8969 C "C5'" . A   C 2 159 ? 131.102 134.484 144.602 1.00 108.54 ? 159 A   C "C5'" 1 
ATOM   8970 C "C4'" . A   C 2 159 ? 130.413 133.321 145.266 1.00 108.54 ? 159 A   C "C4'" 1 
ATOM   8971 O "O4'" . A   C 2 159 ? 130.104 132.311 144.270 1.00 108.54 ? 159 A   C "O4'" 1 
ATOM   8972 C "C3'" . A   C 2 159 ? 131.223 132.616 146.355 1.00 108.54 ? 159 A   C "C3'" 1 
ATOM   8973 O "O3'" . A   C 2 159 ? 130.346 132.217 147.402 1.00 108.54 ? 159 A   C "O3'" 1 
ATOM   8974 C "C2'" . A   C 2 159 ? 131.738 131.369 145.645 1.00 108.54 ? 159 A   C "C2'" 1 
ATOM   8975 O "O2'" . A   C 2 159 ? 131.977 130.283 146.516 1.00 108.54 ? 159 A   C "O2'" 1 
ATOM   8976 C "C1'" . A   C 2 159 ? 130.573 131.058 144.713 1.00 108.54 ? 159 A   C "C1'" 1 
ATOM   8977 N N9    . A   C 2 159 ? 130.949 130.273 143.543 1.00 108.54 ? 159 A   C N9    1 
ATOM   8978 C C8    . A   C 2 159 ? 132.014 130.460 142.699 1.00 108.54 ? 159 A   C C8    1 
ATOM   8979 N N7    . A   C 2 159 ? 132.079 129.584 141.726 1.00 108.54 ? 159 A   C N7    1 
ATOM   8980 C C5    . A   C 2 159 ? 130.980 128.764 141.944 1.00 108.54 ? 159 A   C C5    1 
ATOM   8981 C C6    . A   C 2 159 ? 130.488 127.641 141.259 1.00 108.54 ? 159 A   C C6    1 
ATOM   8982 N N6    . A   C 2 159 ? 131.063 127.129 140.169 1.00 108.54 ? 159 A   C N6    1 
ATOM   8983 N N1    . A   C 2 159 ? 129.372 127.052 141.740 1.00 108.54 ? 159 A   C N1    1 
ATOM   8984 C C2    . A   C 2 159 ? 128.796 127.568 142.832 1.00 108.54 ? 159 A   C C2    1 
ATOM   8985 N N3    . A   C 2 159 ? 129.163 128.617 143.562 1.00 108.54 ? 159 A   C N3    1 
ATOM   8986 C C4    . A   C 2 159 ? 130.276 129.177 143.060 1.00 108.54 ? 159 A   C C4    1 
ATOM   8987 P P     . A   C 2 160 ? 129.963 133.215 148.605 1.00 113.09 ? 160 A   C P     1 
ATOM   8988 O OP1   . A   C 2 160 ? 129.674 134.562 148.055 1.00 113.09 ? 160 A   C OP1   1 
ATOM   8989 O OP2   . A   C 2 160 ? 130.984 133.066 149.671 1.00 113.09 ? 160 A   C OP2   1 
ATOM   8990 O "O5'" . A   C 2 160 ? 128.594 132.607 149.146 1.00 113.09 ? 160 A   C "O5'" 1 
ATOM   8991 C "C5'" . A   C 2 160 ? 127.357 132.919 148.521 1.00 113.09 ? 160 A   C "C5'" 1 
ATOM   8992 C "C4'" . A   C 2 160 ? 127.076 132.004 147.355 1.00 113.09 ? 160 A   C "C4'" 1 
ATOM   8993 O "O4'" . A   C 2 160 ? 127.953 130.849 147.409 1.00 113.09 ? 160 A   C "O4'" 1 
ATOM   8994 C "C3'" . A   C 2 160 ? 125.681 131.402 147.299 1.00 113.09 ? 160 A   C "C3'" 1 
ATOM   8995 O "O3'" . A   C 2 160 ? 124.709 132.287 146.772 1.00 113.09 ? 160 A   C "O3'" 1 
ATOM   8996 C "C2'" . A   C 2 160 ? 125.896 130.155 146.455 1.00 113.09 ? 160 A   C "C2'" 1 
ATOM   8997 O "O2'" . A   C 2 160 ? 125.993 130.494 145.080 1.00 113.09 ? 160 A   C "O2'" 1 
ATOM   8998 C "C1'" . A   C 2 160 ? 127.272 129.705 146.938 1.00 113.09 ? 160 A   C "C1'" 1 
ATOM   8999 N N9    . A   C 2 160 ? 127.173 128.740 148.046 1.00 113.09 ? 160 A   C N9    1 
ATOM   9000 C C8    . A   C 2 160 ? 127.372 128.991 149.380 1.00 113.09 ? 160 A   C C8    1 
ATOM   9001 N N7    . A   C 2 160 ? 127.213 127.941 150.144 1.00 113.09 ? 160 A   C N7    1 
ATOM   9002 C C5    . A   C 2 160 ? 126.886 126.931 149.253 1.00 113.09 ? 160 A   C C5    1 
ATOM   9003 C C6    . A   C 2 160 ? 126.595 125.572 149.441 1.00 113.09 ? 160 A   C C6    1 
ATOM   9004 N N6    . A   C 2 160 ? 126.589 124.985 150.637 1.00 113.09 ? 160 A   C N6    1 
ATOM   9005 N N1    . A   C 2 160 ? 126.308 124.828 148.352 1.00 113.09 ? 160 A   C N1    1 
ATOM   9006 C C2    . A   C 2 160 ? 126.317 125.424 147.153 1.00 113.09 ? 160 A   C C2    1 
ATOM   9007 N N3    . A   C 2 160 ? 126.574 126.697 146.849 1.00 113.09 ? 160 A   C N3    1 
ATOM   9008 C C4    . A   C 2 160 ? 126.854 127.406 147.956 1.00 113.09 ? 160 A   C C4    1 
ATOM   9009 P P     . A   C 2 161 ? 123.174 132.154 147.228 1.00 129.45 ? 161 A   C P     1 
ATOM   9010 O OP1   . A   C 2 161 ? 122.428 133.309 146.668 1.00 129.45 ? 161 A   C OP1   1 
ATOM   9011 O OP2   . A   C 2 161 ? 123.148 131.902 148.690 1.00 129.45 ? 161 A   C OP2   1 
ATOM   9012 O "O5'" . A   C 2 161 ? 122.667 130.834 146.495 1.00 129.45 ? 161 A   C "O5'" 1 
ATOM   9013 C "C5'" . A   C 2 161 ? 122.634 130.759 145.078 1.00 129.45 ? 161 A   C "C5'" 1 
ATOM   9014 C "C4'" . A   C 2 161 ? 122.093 129.436 144.599 1.00 129.45 ? 161 A   C "C4'" 1 
ATOM   9015 O "O4'" . A   C 2 161 ? 123.056 128.380 144.842 1.00 129.45 ? 161 A   C "O4'" 1 
ATOM   9016 C "C3'" . A   C 2 161 ? 120.830 128.940 145.281 1.00 129.45 ? 161 A   C "C3'" 1 
ATOM   9017 O "O3'" . A   C 2 161 ? 119.659 129.567 144.789 1.00 129.45 ? 161 A   C "O3'" 1 
ATOM   9018 C "C2'" . A   C 2 161 ? 120.877 127.440 145.014 1.00 129.45 ? 161 A   C "C2'" 1 
ATOM   9019 O "O2'" . A   C 2 161 ? 120.431 127.151 143.698 1.00 129.45 ? 161 A   C "O2'" 1 
ATOM   9020 C "C1'" . A   C 2 161 ? 122.381 127.163 145.087 1.00 129.45 ? 161 A   C "C1'" 1 
ATOM   9021 N N9    . A   C 2 161 ? 122.789 126.641 146.404 1.00 129.45 ? 161 A   C N9    1 
ATOM   9022 C C8    . A   C 2 161 ? 123.403 127.309 147.434 1.00 129.45 ? 161 A   C C8    1 
ATOM   9023 N N7    . A   C 2 161 ? 123.637 126.559 148.484 1.00 129.45 ? 161 A   C N7    1 
ATOM   9024 C C5    . A   C 2 161 ? 123.145 125.314 148.119 1.00 129.45 ? 161 A   C C5    1 
ATOM   9025 C C6    . A   C 2 161 ? 123.092 124.081 148.792 1.00 129.45 ? 161 A   C C6    1 
ATOM   9026 N N6    . A   C 2 161 ? 123.558 123.894 150.026 1.00 129.45 ? 161 A   C N6    1 
ATOM   9027 N N1    . A   C 2 161 ? 122.537 123.032 148.149 1.00 129.45 ? 161 A   C N1    1 
ATOM   9028 C C2    . A   C 2 161 ? 122.069 123.219 146.909 1.00 129.45 ? 161 A   C C2    1 
ATOM   9029 N N3    . A   C 2 161 ? 122.063 124.328 146.172 1.00 129.45 ? 161 A   C N3    1 
ATOM   9030 C C4    . A   C 2 161 ? 122.621 125.350 146.842 1.00 129.45 ? 161 A   C C4    1 
ATOM   9031 P P     . A   C 2 162 ? 118.375 129.739 145.739 1.00 146.85 ? 162 A   C P     1 
ATOM   9032 O OP1   . A   C 2 162 ? 117.454 130.709 145.094 1.00 146.85 ? 162 A   C OP1   1 
ATOM   9033 O OP2   . A   C 2 162 ? 118.853 129.990 147.122 1.00 146.85 ? 162 A   C OP2   1 
ATOM   9034 O "O5'" . A   C 2 162 ? 117.682 128.306 145.707 1.00 146.85 ? 162 A   C "O5'" 1 
ATOM   9035 C "C5'" . A   C 2 162 ? 117.254 127.734 144.481 1.00 146.85 ? 162 A   C "C5'" 1 
ATOM   9036 C "C4'" . A   C 2 162 ? 116.946 126.267 144.635 1.00 146.85 ? 162 A   C "C4'" 1 
ATOM   9037 O "O4'" . A   C 2 162 ? 118.159 125.542 144.966 1.00 146.85 ? 162 A   C "O4'" 1 
ATOM   9038 C "C3'" . A   C 2 162 ? 115.984 125.903 145.754 1.00 146.85 ? 162 A   C "C3'" 1 
ATOM   9039 O "O3'" . A   C 2 162 ? 114.626 126.094 145.399 1.00 146.85 ? 162 A   C "O3'" 1 
ATOM   9040 C "C2'" . A   C 2 162 ? 116.345 124.453 146.044 1.00 146.85 ? 162 A   C "C2'" 1 
ATOM   9041 O "O2'" . A   C 2 162 ? 115.780 123.591 145.067 1.00 146.85 ? 162 A   C "O2'" 1 
ATOM   9042 C "C1'" . A   C 2 162 ? 117.860 124.478 145.845 1.00 146.85 ? 162 A   C "C1'" 1 
ATOM   9043 N N9    . A   C 2 162 ? 118.578 124.706 147.113 1.00 146.85 ? 162 A   C N9    1 
ATOM   9044 C C8    . A   C 2 162 ? 119.084 125.890 147.586 1.00 146.85 ? 162 A   C C8    1 
ATOM   9045 N N7    . A   C 2 162 ? 119.674 125.785 148.751 1.00 146.85 ? 162 A   C N7    1 
ATOM   9046 C C5    . A   C 2 162 ? 119.547 124.440 149.067 1.00 146.85 ? 162 A   C C5    1 
ATOM   9047 C C6    . A   C 2 162 ? 119.965 123.687 150.176 1.00 146.85 ? 162 A   C C6    1 
ATOM   9048 N N6    . A   C 2 162 ? 120.624 124.208 151.213 1.00 146.85 ? 162 A   C N6    1 
ATOM   9049 N N1    . A   C 2 162 ? 119.682 122.366 150.186 1.00 146.85 ? 162 A   C N1    1 
ATOM   9050 C C2    . A   C 2 162 ? 119.021 121.848 149.144 1.00 146.85 ? 162 A   C C2    1 
ATOM   9051 N N3    . A   C 2 162 ? 118.575 122.452 148.044 1.00 146.85 ? 162 A   C N3    1 
ATOM   9052 C C4    . A   C 2 162 ? 118.873 123.763 148.068 1.00 146.85 ? 162 A   C C4    1 
ATOM   9053 P P     . G   C 2 163 ? 113.565 126.576 146.504 1.00 161.98 ? 163 G   C P     1 
ATOM   9054 O OP1   . G   C 2 163 ? 112.323 126.986 145.801 1.00 161.98 ? 163 G   C OP1   1 
ATOM   9055 O OP2   . G   C 2 163 ? 114.247 127.534 147.409 1.00 161.98 ? 163 G   C OP2   1 
ATOM   9056 O "O5'" . G   C 2 163 ? 113.250 125.254 147.334 1.00 161.98 ? 163 G   C "O5'" 1 
ATOM   9057 C "C5'" . G   C 2 163 ? 112.706 124.109 146.697 1.00 161.98 ? 163 G   C "C5'" 1 
ATOM   9058 C "C4'" . G   C 2 163 ? 112.809 122.886 147.572 1.00 161.98 ? 163 G   C "C4'" 1 
ATOM   9059 O "O4'" . G   C 2 163 ? 114.204 122.546 147.783 1.00 161.98 ? 163 G   C "O4'" 1 
ATOM   9060 C "C3'" . G   C 2 163 ? 112.249 123.022 148.978 1.00 161.98 ? 163 G   C "C3'" 1 
ATOM   9061 O "O3'" . G   C 2 163 ? 110.840 122.878 149.029 1.00 161.98 ? 163 G   C "O3'" 1 
ATOM   9062 C "C2'" . G   C 2 163 ? 113.001 121.941 149.742 1.00 161.98 ? 163 G   C "C2'" 1 
ATOM   9063 O "O2'" . G   C 2 163 ? 112.439 120.663 149.486 1.00 161.98 ? 163 G   C "O2'" 1 
ATOM   9064 C "C1'" . G   C 2 163 ? 114.376 122.004 149.076 1.00 161.98 ? 163 G   C "C1'" 1 
ATOM   9065 N N9    . G   C 2 163 ? 115.317 122.857 149.827 1.00 161.98 ? 163 G   C N9    1 
ATOM   9066 C C8    . G   C 2 163 ? 115.761 124.112 149.489 1.00 161.98 ? 163 G   C C8    1 
ATOM   9067 N N7    . G   C 2 163 ? 116.596 124.610 150.361 1.00 161.98 ? 163 G   C N7    1 
ATOM   9068 C C5    . G   C 2 163 ? 116.710 123.625 151.331 1.00 161.98 ? 163 G   C C5    1 
ATOM   9069 C C6    . G   C 2 163 ? 117.475 123.590 152.525 1.00 161.98 ? 163 G   C C6    1 
ATOM   9070 O O6    . G   C 2 163 ? 118.230 124.459 152.976 1.00 161.98 ? 163 G   C O6    1 
ATOM   9071 N N1    . G   C 2 163 ? 117.296 122.396 153.216 1.00 161.98 ? 163 G   C N1    1 
ATOM   9072 C C2    . G   C 2 163 ? 116.485 121.364 152.813 1.00 161.98 ? 163 G   C C2    1 
ATOM   9073 N N2    . G   C 2 163 ? 116.431 120.282 153.602 1.00 161.98 ? 163 G   C N2    1 
ATOM   9074 N N3    . G   C 2 163 ? 115.769 121.386 151.701 1.00 161.98 ? 163 G   C N3    1 
ATOM   9075 C C4    . G   C 2 163 ? 115.928 122.537 151.015 1.00 161.98 ? 163 G   C C4    1 
ATOM   9076 P P     . A   C 2 164 ? 109.985 123.696 150.115 1.00 175.31 ? 164 A   C P     1 
ATOM   9077 O OP1   . A   C 2 164 ? 108.545 123.509 149.806 1.00 175.31 ? 164 A   C OP1   1 
ATOM   9078 O OP2   . A   C 2 164 ? 110.548 125.068 150.202 1.00 175.31 ? 164 A   C OP2   1 
ATOM   9079 O "O5'" . A   C 2 164 ? 110.294 122.950 151.488 1.00 175.31 ? 164 A   C "O5'" 1 
ATOM   9080 C "C5'" . A   C 2 164 ? 109.938 121.589 151.677 1.00 175.31 ? 164 A   C "C5'" 1 
ATOM   9081 C "C4'" . A   C 2 164 ? 110.489 121.052 152.973 1.00 175.31 ? 164 A   C "C4'" 1 
ATOM   9082 O "O4'" . A   C 2 164 ? 111.938 120.991 152.903 1.00 175.31 ? 164 A   C "O4'" 1 
ATOM   9083 C "C3'" . A   C 2 164 ? 110.212 121.894 154.207 1.00 175.31 ? 164 A   C "C3'" 1 
ATOM   9084 O "O3'" . A   C 2 164 ? 108.919 121.677 154.743 1.00 175.31 ? 164 A   C "O3'" 1 
ATOM   9085 C "C2'" . A   C 2 164 ? 111.342 121.494 155.146 1.00 175.31 ? 164 A   C "C2'" 1 
ATOM   9086 O "O2'" . A   C 2 164 ? 111.066 120.242 155.757 1.00 175.31 ? 164 A   C "O2'" 1 
ATOM   9087 C "C1'" . A   C 2 164 ? 112.497 121.305 154.162 1.00 175.31 ? 164 A   C "C1'" 1 
ATOM   9088 N N9    . A   C 2 164 ? 113.304 122.530 154.014 1.00 175.31 ? 164 A   C N9    1 
ATOM   9089 C C8    . A   C 2 164 ? 113.266 123.421 152.971 1.00 175.31 ? 164 A   C C8    1 
ATOM   9090 N N7    . A   C 2 164 ? 114.097 124.425 153.100 1.00 175.31 ? 164 A   C N7    1 
ATOM   9091 C C5    . A   C 2 164 ? 114.725 124.178 154.311 1.00 175.31 ? 164 A   C C5    1 
ATOM   9092 C C6    . A   C 2 164 ? 115.717 124.880 155.014 1.00 175.31 ? 164 A   C C6    1 
ATOM   9093 N N6    . A   C 2 164 ? 116.260 126.013 154.571 1.00 175.31 ? 164 A   C N6    1 
ATOM   9094 N N1    . A   C 2 164 ? 116.135 124.376 156.195 1.00 175.31 ? 164 A   C N1    1 
ATOM   9095 C C2    . A   C 2 164 ? 115.582 123.236 156.633 1.00 175.31 ? 164 A   C C2    1 
ATOM   9096 N N3    . A   C 2 164 ? 114.642 122.483 156.061 1.00 175.31 ? 164 A   C N3    1 
ATOM   9097 C C4    . A   C 2 164 ? 114.250 123.015 154.888 1.00 175.31 ? 164 A   C C4    1 
ATOM   9098 P P     . G   C 2 165 ? 108.029 122.922 155.233 1.00 181.60 ? 165 G   C P     1 
ATOM   9099 O OP1   . G   C 2 165 ? 106.688 122.808 154.606 1.00 181.60 ? 165 G   C OP1   1 
ATOM   9100 O OP2   . G   C 2 165 ? 108.827 124.160 155.042 1.00 181.60 ? 165 G   C OP2   1 
ATOM   9101 O "O5'" . G   C 2 165 ? 107.865 122.681 156.798 1.00 181.60 ? 165 G   C "O5'" 1 
ATOM   9102 C "C5'" . G   C 2 165 ? 107.720 123.773 157.692 1.00 181.60 ? 165 G   C "C5'" 1 
ATOM   9103 C "C4'" . G   C 2 165 ? 108.689 123.669 158.841 1.00 181.60 ? 165 G   C "C4'" 1 
ATOM   9104 O "O4'" . G   C 2 165 ? 110.018 123.382 158.332 1.00 181.60 ? 165 G   C "O4'" 1 
ATOM   9105 C "C3'" . G   C 2 165 ? 108.877 124.929 159.671 1.00 181.60 ? 165 G   C "C3'" 1 
ATOM   9106 O "O3'" . G   C 2 165 ? 107.857 125.120 160.637 1.00 181.60 ? 165 G   C "O3'" 1 
ATOM   9107 C "C2'" . G   C 2 165 ? 110.260 124.724 160.272 1.00 181.60 ? 165 G   C "C2'" 1 
ATOM   9108 O "O2'" . G   C 2 165 ? 110.205 123.814 161.361 1.00 181.60 ? 165 G   C "O2'" 1 
ATOM   9109 C "C1'" . G   C 2 165 ? 110.988 124.045 159.115 1.00 181.60 ? 165 G   C "C1'" 1 
ATOM   9110 N N9    . G   C 2 165 ? 111.689 125.019 158.257 1.00 181.60 ? 165 G   C N9    1 
ATOM   9111 C C8    . G   C 2 165 ? 111.279 125.470 157.026 1.00 181.60 ? 165 G   C C8    1 
ATOM   9112 N N7    . G   C 2 165 ? 112.104 126.328 156.494 1.00 181.60 ? 165 G   C N7    1 
ATOM   9113 C C5    . G   C 2 165 ? 113.121 126.451 157.429 1.00 181.60 ? 165 G   C C5    1 
ATOM   9114 C C6    . G   C 2 165 ? 114.295 127.245 157.405 1.00 181.60 ? 165 G   C C6    1 
ATOM   9115 O O6    . G   C 2 165 ? 114.690 128.025 156.533 1.00 181.60 ? 165 G   C O6    1 
ATOM   9116 N N1    . G   C 2 165 ? 115.052 127.074 158.557 1.00 181.60 ? 165 G   C N1    1 
ATOM   9117 C C2    . G   C 2 165 ? 114.726 126.242 159.597 1.00 181.60 ? 165 G   C C2    1 
ATOM   9118 N N2    . G   C 2 165 ? 115.599 126.229 160.613 1.00 181.60 ? 165 G   C N2    1 
ATOM   9119 N N3    . G   C 2 165 ? 113.634 125.496 159.636 1.00 181.60 ? 165 G   C N3    1 
ATOM   9120 C C4    . G   C 2 165 ? 112.882 125.649 158.525 1.00 181.60 ? 165 G   C C4    1 
ATOM   9121 P P     . A   C 2 166 ? 107.593 126.582 161.250 1.00 188.49 ? 166 A   C P     1 
ATOM   9122 O OP1   . A   C 2 166 ? 106.127 126.818 161.252 1.00 188.49 ? 166 A   C OP1   1 
ATOM   9123 O OP2   . A   C 2 166 ? 108.489 127.541 160.555 1.00 188.49 ? 166 A   C OP2   1 
ATOM   9124 O "O5'" . A   C 2 166 ? 108.079 126.459 162.762 1.00 188.49 ? 166 A   C "O5'" 1 
ATOM   9125 C "C5'" . A   C 2 166 ? 108.887 127.465 163.358 1.00 188.49 ? 166 A   C "C5'" 1 
ATOM   9126 C "C4'" . A   C 2 166 ? 110.304 126.984 163.545 1.00 188.49 ? 166 A   C "C4'" 1 
ATOM   9127 O "O4'" . A   C 2 166 ? 110.975 126.940 162.262 1.00 188.49 ? 166 A   C "O4'" 1 
ATOM   9128 C "C3'" . A   C 2 166 ? 111.208 127.858 164.396 1.00 188.49 ? 166 A   C "C3'" 1 
ATOM   9129 O "O3'" . A   C 2 166 ? 111.007 127.670 165.786 1.00 188.49 ? 166 A   C "O3'" 1 
ATOM   9130 C "C2'" . A   C 2 166 ? 112.598 127.458 163.917 1.00 188.49 ? 166 A   C "C2'" 1 
ATOM   9131 O "O2'" . A   C 2 166 ? 112.995 126.227 164.503 1.00 188.49 ? 166 A   C "O2'" 1 
ATOM   9132 C "C1'" . A   C 2 166 ? 112.348 127.224 162.425 1.00 188.49 ? 166 A   C "C1'" 1 
ATOM   9133 N N9    . A   C 2 166 ? 112.693 128.405 161.611 1.00 188.49 ? 166 A   C N9    1 
ATOM   9134 C C8    . A   C 2 166 ? 113.604 129.385 161.916 1.00 188.49 ? 166 A   C C8    1 
ATOM   9135 N N7    . A   C 2 166 ? 113.718 130.311 160.997 1.00 188.49 ? 166 A   C N7    1 
ATOM   9136 C C5    . A   C 2 166 ? 112.827 129.912 160.012 1.00 188.49 ? 166 A   C C5    1 
ATOM   9137 C C6    . A   C 2 166 ? 112.478 130.475 158.772 1.00 188.49 ? 166 A   C C6    1 
ATOM   9138 N N6    . A   C 2 166 ? 113.009 131.604 158.296 1.00 188.49 ? 166 A   C N6    1 
ATOM   9139 N N1    . A   C 2 166 ? 111.554 129.831 158.026 1.00 188.49 ? 166 A   C N1    1 
ATOM   9140 C C2    . A   C 2 166 ? 111.022 128.701 158.505 1.00 188.49 ? 166 A   C C2    1 
ATOM   9141 N N3    . A   C 2 166 ? 111.269 128.074 159.653 1.00 188.49 ? 166 A   C N3    1 
ATOM   9142 C C4    . A   C 2 166 ? 112.194 128.735 160.371 1.00 188.49 ? 166 A   C C4    1 
ATOM   9143 P P     . C   C 2 167 ? 110.370 128.851 166.669 1.00 195.49 ? 167 C   C P     1 
ATOM   9144 O OP1   . C   C 2 167 ? 111.477 129.582 167.335 1.00 195.49 ? 167 C   C OP1   1 
ATOM   9145 O OP2   . C   C 2 167 ? 109.274 128.274 167.489 1.00 195.49 ? 167 C   C OP2   1 
ATOM   9146 O "O5'" . C   C 2 167 ? 109.717 129.818 165.586 1.00 195.49 ? 167 C   C "O5'" 1 
ATOM   9147 C "C5'" . C   C 2 167 ? 109.179 131.083 165.956 1.00 195.49 ? 167 C   C "C5'" 1 
ATOM   9148 C "C4'" . C   C 2 167 ? 109.514 132.151 164.943 1.00 195.49 ? 167 C   C "C4'" 1 
ATOM   9149 O "O4'" . C   C 2 167 ? 110.922 132.498 165.057 1.00 195.49 ? 167 C   C "O4'" 1 
ATOM   9150 C "C3'" . C   C 2 167 ? 109.286 131.767 163.481 1.00 195.49 ? 167 C   C "C3'" 1 
ATOM   9151 O "O3'" . C   C 2 167 ? 108.867 132.917 162.751 1.00 195.49 ? 167 C   C "O3'" 1 
ATOM   9152 C "C2'" . C   C 2 167 ? 110.682 131.363 163.018 1.00 195.49 ? 167 C   C "C2'" 1 
ATOM   9153 O "O2'" . C   C 2 167 ? 110.891 131.480 161.627 1.00 195.49 ? 167 C   C "O2'" 1 
ATOM   9154 C "C1'" . C   C 2 167 ? 111.557 132.333 163.804 1.00 195.49 ? 167 C   C "C1'" 1 
ATOM   9155 N N1    . C   C 2 167 ? 112.925 131.849 164.042 1.00 195.49 ? 167 C   C N1    1 
ATOM   9156 C C2    . C   C 2 167 ? 113.977 132.434 163.334 1.00 195.49 ? 167 C   C C2    1 
ATOM   9157 O O2    . C   C 2 167 ? 113.724 133.340 162.527 1.00 195.49 ? 167 C   C O2    1 
ATOM   9158 N N3    . C   C 2 167 ? 115.240 131.995 163.544 1.00 195.49 ? 167 C   C N3    1 
ATOM   9159 C C4    . C   C 2 167 ? 115.468 131.016 164.421 1.00 195.49 ? 167 C   C C4    1 
ATOM   9160 N N4    . C   C 2 167 ? 116.729 130.615 164.597 1.00 195.49 ? 167 C   C N4    1 
ATOM   9161 C C5    . C   C 2 167 ? 114.413 130.403 165.157 1.00 195.49 ? 167 C   C C5    1 
ATOM   9162 C C6    . C   C 2 167 ? 113.169 130.847 164.939 1.00 195.49 ? 167 C   C C6    1 
ATOM   9163 P P     . C   C 2 168 ? 107.552 132.864 161.830 1.00 205.65 ? 168 C   C P     1 
ATOM   9164 O OP1   . C   C 2 168 ? 106.740 131.695 162.251 1.00 205.65 ? 168 C   C OP1   1 
ATOM   9165 O OP2   . C   C 2 168 ? 107.978 132.990 160.413 1.00 205.65 ? 168 C   C OP2   1 
ATOM   9166 O "O5'" . C   C 2 168 ? 106.761 134.189 162.226 1.00 205.65 ? 168 C   C "O5'" 1 
ATOM   9167 C "C5'" . C   C 2 168 ? 106.093 134.289 163.474 1.00 205.65 ? 168 C   C "C5'" 1 
ATOM   9168 C "C4'" . C   C 2 168 ? 106.635 135.425 164.305 1.00 205.65 ? 168 C   C "C4'" 1 
ATOM   9169 O "O4'" . C   C 2 168 ? 108.034 135.193 164.606 1.00 205.65 ? 168 C   C "O4'" 1 
ATOM   9170 C "C3'" . C   C 2 168 ? 106.622 136.800 163.656 1.00 205.65 ? 168 C   C "C3'" 1 
ATOM   9171 O "O3'" . C   C 2 168 ? 105.353 137.426 163.720 1.00 205.65 ? 168 C   C "O3'" 1 
ATOM   9172 C "C2'" . C   C 2 168 ? 107.705 137.544 164.430 1.00 205.65 ? 168 C   C "C2'" 1 
ATOM   9173 O "O2'" . C   C 2 168 ? 107.205 138.005 165.676 1.00 205.65 ? 168 C   C "O2'" 1 
ATOM   9174 C "C1'" . C   C 2 168 ? 108.717 136.426 164.699 1.00 205.65 ? 168 C   C "C1'" 1 
ATOM   9175 N N1    . C   C 2 168 ? 109.842 136.435 163.734 1.00 205.65 ? 168 C   C N1    1 
ATOM   9176 C C2    . C   C 2 168 ? 110.998 137.140 164.078 1.00 205.65 ? 168 C   C C2    1 
ATOM   9177 O O2    . C   C 2 168 ? 111.039 137.724 165.171 1.00 205.65 ? 168 C   C O2    1 
ATOM   9178 N N3    . C   C 2 168 ? 112.041 137.164 163.217 1.00 205.65 ? 168 C   C N3    1 
ATOM   9179 C C4    . C   C 2 168 ? 111.960 136.521 162.051 1.00 205.65 ? 168 C   C C4    1 
ATOM   9180 N N4    . C   C 2 168 ? 113.013 136.573 161.232 1.00 205.65 ? 168 C   C N4    1 
ATOM   9181 C C5    . C   C 2 168 ? 110.794 135.796 161.673 1.00 205.65 ? 168 C   C C5    1 
ATOM   9182 C C6    . C   C 2 168 ? 109.770 135.782 162.536 1.00 205.65 ? 168 C   C C6    1 
ATOM   9183 P P     . A   C 2 169 ? 104.528 137.733 162.375 1.00 210.31 ? 169 A   C P     1 
ATOM   9184 O OP1   . A   C 2 169 ? 105.417 138.483 161.451 1.00 210.31 ? 169 A   C OP1   1 
ATOM   9185 O OP2   . A   C 2 169 ? 103.217 138.312 162.762 1.00 210.31 ? 169 A   C OP2   1 
ATOM   9186 O "O5'" . A   C 2 169 ? 104.265 136.294 161.744 1.00 210.31 ? 169 A   C "O5'" 1 
ATOM   9187 C "C5'" . A   C 2 169 ? 103.148 136.060 160.900 1.00 210.31 ? 169 A   C "C5'" 1 
ATOM   9188 C "C4'" . A   C 2 169 ? 103.574 135.568 159.540 1.00 210.31 ? 169 A   C "C4'" 1 
ATOM   9189 O "O4'" . A   C 2 169 ? 104.278 136.625 158.837 1.00 210.31 ? 169 A   C "O4'" 1 
ATOM   9190 C "C3'" . A   C 2 169 ? 104.550 134.402 159.527 1.00 210.31 ? 169 A   C "C3'" 1 
ATOM   9191 O "O3'" . A   C 2 169 ? 103.917 133.148 159.708 1.00 210.31 ? 169 A   C "O3'" 1 
ATOM   9192 C "C2'" . A   C 2 169 ? 105.231 134.553 158.173 1.00 210.31 ? 169 A   C "C2'" 1 
ATOM   9193 O "O2'" . A   C 2 169 ? 104.398 134.056 157.135 1.00 210.31 ? 169 A   C "O2'" 1 
ATOM   9194 C "C1'" . A   C 2 169 ? 105.307 136.075 158.042 1.00 210.31 ? 169 A   C "C1'" 1 
ATOM   9195 N N9    . A   C 2 169 ? 106.599 136.608 158.515 1.00 210.31 ? 169 A   C N9    1 
ATOM   9196 C C8    . A   C 2 169 ? 107.627 135.925 159.116 1.00 210.31 ? 169 A   C C8    1 
ATOM   9197 N N7    . A   C 2 169 ? 108.654 136.680 159.422 1.00 210.31 ? 169 A   C N7    1 
ATOM   9198 C C5    . A   C 2 169 ? 108.279 137.944 158.992 1.00 210.31 ? 169 A   C C5    1 
ATOM   9199 C C6    . A   C 2 169 ? 108.931 139.190 159.028 1.00 210.31 ? 169 A   C C6    1 
ATOM   9200 N N6    . A   C 2 169 ? 110.150 139.373 159.539 1.00 210.31 ? 169 A   C N6    1 
ATOM   9201 N N1    . A   C 2 169 ? 108.278 140.256 158.514 1.00 210.31 ? 169 A   C N1    1 
ATOM   9202 C C2    . A   C 2 169 ? 107.055 140.073 158.001 1.00 210.31 ? 169 A   C C2    1 
ATOM   9203 N N3    . A   C 2 169 ? 106.340 138.954 157.911 1.00 210.31 ? 169 A   C N3    1 
ATOM   9204 C C4    . A   C 2 169 ? 107.016 137.914 158.429 1.00 210.31 ? 169 A   C C4    1 
HETATM 9205 P PG    . ATP D 3 .   ? 138.162 150.665 127.790 1.00 67.67  ? 401 ATP B PG    1 
HETATM 9206 O O1G   . ATP D 3 .   ? 139.233 150.187 126.869 1.00 67.67  ? 401 ATP B O1G   1 
HETATM 9207 O O2G   . ATP D 3 .   ? 136.787 150.050 127.508 1.00 67.67  ? 401 ATP B O2G   1 
HETATM 9208 O O3G   . ATP D 3 .   ? 138.500 150.478 129.274 1.00 67.67  ? 401 ATP B O3G   1 
HETATM 9209 P PB    . ATP D 3 .   ? 137.482 153.503 128.481 1.00 67.67  ? 401 ATP B PB    1 
HETATM 9210 O O1B   . ATP D 3 .   ? 138.337 154.681 128.231 1.00 67.67  ? 401 ATP B O1B   1 
HETATM 9211 O O2B   . ATP D 3 .   ? 137.391 153.051 129.937 1.00 67.67  ? 401 ATP B O2B   1 
HETATM 9212 O O3B   . ATP D 3 .   ? 137.939 152.241 127.624 1.00 67.67  ? 401 ATP B O3B   1 
HETATM 9213 P PA    . ATP D 3 .   ? 134.837 154.796 128.172 1.00 67.67  ? 401 ATP B PA    1 
HETATM 9214 O O1A   . ATP D 3 .   ? 133.801 154.304 129.103 1.00 67.67  ? 401 ATP B O1A   1 
HETATM 9215 O O2A   . ATP D 3 .   ? 134.320 155.176 126.784 1.00 67.67  ? 401 ATP B O2A   1 
HETATM 9216 O O3A   . ATP D 3 .   ? 135.993 153.722 127.964 1.00 67.67  ? 401 ATP B O3A   1 
HETATM 9217 O "O5'" . ATP D 3 .   ? 135.603 156.039 128.774 1.00 67.67  ? 401 ATP B "O5'" 1 
HETATM 9218 C "C5'" . ATP D 3 .   ? 135.043 156.810 129.857 1.00 67.67  ? 401 ATP B "C5'" 1 
HETATM 9219 C "C4'" . ATP D 3 .   ? 135.656 158.187 129.849 1.00 67.67  ? 401 ATP B "C4'" 1 
HETATM 9220 O "O4'" . ATP D 3 .   ? 135.661 158.707 128.501 1.00 67.67  ? 401 ATP B "O4'" 1 
HETATM 9221 C "C3'" . ATP D 3 .   ? 134.924 159.227 130.693 1.00 67.67  ? 401 ATP B "C3'" 1 
HETATM 9222 O "O3'" . ATP D 3 .   ? 135.828 160.183 131.234 1.00 67.67  ? 401 ATP B "O3'" 1 
HETATM 9223 C "C2'" . ATP D 3 .   ? 133.969 159.863 129.683 1.00 67.67  ? 401 ATP B "C2'" 1 
HETATM 9224 O "O2'" . ATP D 3 .   ? 133.661 161.205 130.041 1.00 67.67  ? 401 ATP B "O2'" 1 
HETATM 9225 C "C1'" . ATP D 3 .   ? 134.811 159.837 128.406 1.00 67.67  ? 401 ATP B "C1'" 1 
HETATM 9226 N N9    . ATP D 3 .   ? 134.028 159.721 127.180 1.00 67.67  ? 401 ATP B N9    1 
HETATM 9227 C C8    . ATP D 3 .   ? 133.454 158.584 126.672 1.00 67.67  ? 401 ATP B C8    1 
HETATM 9228 N N7    . ATP D 3 .   ? 132.803 158.769 125.550 1.00 67.67  ? 401 ATP B N7    1 
HETATM 9229 C C5    . ATP D 3 .   ? 132.958 160.124 125.299 1.00 67.67  ? 401 ATP B C5    1 
HETATM 9230 C C6    . ATP D 3 .   ? 132.506 160.956 124.258 1.00 67.67  ? 401 ATP B C6    1 
HETATM 9231 N N6    . ATP D 3 .   ? 131.771 160.526 123.227 1.00 67.67  ? 401 ATP B N6    1 
HETATM 9232 N N1    . ATP D 3 .   ? 132.837 162.265 124.309 1.00 67.67  ? 401 ATP B N1    1 
HETATM 9233 C C2    . ATP D 3 .   ? 133.571 162.702 125.336 1.00 67.67  ? 401 ATP B C2    1 
HETATM 9234 N N3    . ATP D 3 .   ? 134.053 162.013 126.373 1.00 67.67  ? 401 ATP B N3    1 
HETATM 9235 C C4    . ATP D 3 .   ? 133.711 160.723 126.297 1.00 67.67  ? 401 ATP B C4    1 
# 
