data_8ZIU
# 
_entry.id   8ZIU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZIU         pdb_00008ziu 10.2210/pdb8ziu/pdb 
WWPDB D_1300047841 ?            ?                   
EMDB  EMD-60130    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-29 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZIU 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-14 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Mouse MYH6 R404Q left ventricle actin and myosin complex' 
_pdbx_database_related.db_id          EMD-60130 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              dannielee@sjtu.edu.cn 
_pdbx_contact_author.name_first         Cong 
_pdbx_contact_author.name_last          Liu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3425-6672 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, D.N.'   1 ? 
'Zhao, Q.Y.' 2 ? 
'Liu, C.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Mouse MYH6 R404Q left ventricle actin and myosin complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, D.N.'   1 ? 
primary 'Zhao, Q.Y.' 2 ? 
primary 'Liu, C.'    3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     nat 'Actin, alpha cardiac muscle 1' 41194.973 1 3.6.4.- ? ? ? 
2 polymer     nat Myosin-6                        87693.883 1 ?       ? ? ? 
3 non-polymer syn "ADENOSINE-5'-DIPHOSPHATE"      427.201   1 ?       ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Alpha-cardiac actin'                                                             
2 'Myosin heavy chain 6,Myosin heavy chain,cardiac muscle alpha isoform,MyHC-alpha' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEK
IWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVP
IYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPD
GQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPST
MKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKC
;
;TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEK
IWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVP
IYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPD
GQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPST
MKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKC
;
J ? 
2 'polypeptide(L)' no no 
;AQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKVVSREGGKVTAETENGKTVTIKEDQVMQQNPPK
FDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQ
YMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENPNANKGTLEDQIIQANPALEAFGNAKTVRNDNSS
RFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVAS
IDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHP
QVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTN
EKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLYDNHLGKSNN
FQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGKGGKKKG
SSFQTVSALHRENLNKLMTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQR
YRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLL
;
;AQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKVVSREGGKVTAETENGKTVTIKEDQVMQQNPPK
FDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQ
YMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENPNANKGTLEDQIIQANPALEAFGNAKTVRNDNSS
RFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVAS
IDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHP
QVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTN
EKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLYDNHLGKSNN
FQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGKGGKKKG
SSFQTVSALHRENLNKLMTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQR
YRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLL
;
C ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        "ADENOSINE-5'-DIPHOSPHATE" 
_pdbx_entity_nonpoly.comp_id     ADP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   THR n 
1 2   THR n 
1 3   ALA n 
1 4   LEU n 
1 5   VAL n 
1 6   CYS n 
1 7   ASP n 
1 8   ASN n 
1 9   GLY n 
1 10  SER n 
1 11  GLY n 
1 12  LEU n 
1 13  VAL n 
1 14  LYS n 
1 15  ALA n 
1 16  GLY n 
1 17  PHE n 
1 18  ALA n 
1 19  GLY n 
1 20  ASP n 
1 21  ASP n 
1 22  ALA n 
1 23  PRO n 
1 24  ARG n 
1 25  ALA n 
1 26  VAL n 
1 27  PHE n 
1 28  PRO n 
1 29  SER n 
1 30  ILE n 
1 31  VAL n 
1 32  GLY n 
1 33  ARG n 
1 34  PRO n 
1 35  ARG n 
1 36  HIS n 
1 37  GLN n 
1 38  GLY n 
1 39  VAL n 
1 40  MET n 
1 41  VAL n 
1 42  GLY n 
1 43  MET n 
1 44  GLY n 
1 45  GLN n 
1 46  LYS n 
1 47  ASP n 
1 48  SER n 
1 49  TYR n 
1 50  VAL n 
1 51  GLY n 
1 52  ASP n 
1 53  GLU n 
1 54  ALA n 
1 55  GLN n 
1 56  SER n 
1 57  LYS n 
1 58  ARG n 
1 59  GLY n 
1 60  ILE n 
1 61  LEU n 
1 62  THR n 
1 63  LEU n 
1 64  LYS n 
1 65  TYR n 
1 66  PRO n 
1 67  ILE n 
1 68  GLU n 
1 69  HIS n 
1 70  GLY n 
1 71  ILE n 
1 72  ILE n 
1 73  THR n 
1 74  ASN n 
1 75  TRP n 
1 76  ASP n 
1 77  ASP n 
1 78  MET n 
1 79  GLU n 
1 80  LYS n 
1 81  ILE n 
1 82  TRP n 
1 83  HIS n 
1 84  HIS n 
1 85  THR n 
1 86  PHE n 
1 87  TYR n 
1 88  ASN n 
1 89  GLU n 
1 90  LEU n 
1 91  ARG n 
1 92  VAL n 
1 93  ALA n 
1 94  PRO n 
1 95  GLU n 
1 96  GLU n 
1 97  HIS n 
1 98  PRO n 
1 99  THR n 
1 100 LEU n 
1 101 LEU n 
1 102 THR n 
1 103 GLU n 
1 104 ALA n 
1 105 PRO n 
1 106 LEU n 
1 107 ASN n 
1 108 PRO n 
1 109 LYS n 
1 110 ALA n 
1 111 ASN n 
1 112 ARG n 
1 113 GLU n 
1 114 LYS n 
1 115 MET n 
1 116 THR n 
1 117 GLN n 
1 118 ILE n 
1 119 MET n 
1 120 PHE n 
1 121 GLU n 
1 122 THR n 
1 123 PHE n 
1 124 ASN n 
1 125 VAL n 
1 126 PRO n 
1 127 ALA n 
1 128 MET n 
1 129 TYR n 
1 130 VAL n 
1 131 ALA n 
1 132 ILE n 
1 133 GLN n 
1 134 ALA n 
1 135 VAL n 
1 136 LEU n 
1 137 SER n 
1 138 LEU n 
1 139 TYR n 
1 140 ALA n 
1 141 SER n 
1 142 GLY n 
1 143 ARG n 
1 144 THR n 
1 145 THR n 
1 146 GLY n 
1 147 ILE n 
1 148 VAL n 
1 149 LEU n 
1 150 ASP n 
1 151 SER n 
1 152 GLY n 
1 153 ASP n 
1 154 GLY n 
1 155 VAL n 
1 156 THR n 
1 157 HIS n 
1 158 ASN n 
1 159 VAL n 
1 160 PRO n 
1 161 ILE n 
1 162 TYR n 
1 163 GLU n 
1 164 GLY n 
1 165 TYR n 
1 166 ALA n 
1 167 LEU n 
1 168 PRO n 
1 169 HIS n 
1 170 ALA n 
1 171 ILE n 
1 172 MET n 
1 173 ARG n 
1 174 LEU n 
1 175 ASP n 
1 176 LEU n 
1 177 ALA n 
1 178 GLY n 
1 179 ARG n 
1 180 ASP n 
1 181 LEU n 
1 182 THR n 
1 183 ASP n 
1 184 TYR n 
1 185 LEU n 
1 186 MET n 
1 187 LYS n 
1 188 ILE n 
1 189 LEU n 
1 190 THR n 
1 191 GLU n 
1 192 ARG n 
1 193 GLY n 
1 194 TYR n 
1 195 SER n 
1 196 PHE n 
1 197 VAL n 
1 198 THR n 
1 199 THR n 
1 200 ALA n 
1 201 GLU n 
1 202 ARG n 
1 203 GLU n 
1 204 ILE n 
1 205 VAL n 
1 206 ARG n 
1 207 ASP n 
1 208 ILE n 
1 209 LYS n 
1 210 GLU n 
1 211 LYS n 
1 212 LEU n 
1 213 CYS n 
1 214 TYR n 
1 215 VAL n 
1 216 ALA n 
1 217 LEU n 
1 218 ASP n 
1 219 PHE n 
1 220 GLU n 
1 221 ASN n 
1 222 GLU n 
1 223 MET n 
1 224 ALA n 
1 225 THR n 
1 226 ALA n 
1 227 ALA n 
1 228 SER n 
1 229 SER n 
1 230 SER n 
1 231 SER n 
1 232 LEU n 
1 233 GLU n 
1 234 LYS n 
1 235 SER n 
1 236 TYR n 
1 237 GLU n 
1 238 LEU n 
1 239 PRO n 
1 240 ASP n 
1 241 GLY n 
1 242 GLN n 
1 243 VAL n 
1 244 ILE n 
1 245 THR n 
1 246 ILE n 
1 247 GLY n 
1 248 ASN n 
1 249 GLU n 
1 250 ARG n 
1 251 PHE n 
1 252 ARG n 
1 253 CYS n 
1 254 PRO n 
1 255 GLU n 
1 256 THR n 
1 257 LEU n 
1 258 PHE n 
1 259 GLN n 
1 260 PRO n 
1 261 SER n 
1 262 PHE n 
1 263 ILE n 
1 264 GLY n 
1 265 MET n 
1 266 GLU n 
1 267 SER n 
1 268 ALA n 
1 269 GLY n 
1 270 ILE n 
1 271 HIS n 
1 272 GLU n 
1 273 THR n 
1 274 THR n 
1 275 TYR n 
1 276 ASN n 
1 277 SER n 
1 278 ILE n 
1 279 MET n 
1 280 LYS n 
1 281 CYS n 
1 282 ASP n 
1 283 ILE n 
1 284 ASP n 
1 285 ILE n 
1 286 ARG n 
1 287 LYS n 
1 288 ASP n 
1 289 LEU n 
1 290 TYR n 
1 291 ALA n 
1 292 ASN n 
1 293 ASN n 
1 294 VAL n 
1 295 LEU n 
1 296 SER n 
1 297 GLY n 
1 298 GLY n 
1 299 THR n 
1 300 THR n 
1 301 MET n 
1 302 TYR n 
1 303 PRO n 
1 304 GLY n 
1 305 ILE n 
1 306 ALA n 
1 307 ASP n 
1 308 ARG n 
1 309 MET n 
1 310 GLN n 
1 311 LYS n 
1 312 GLU n 
1 313 ILE n 
1 314 THR n 
1 315 ALA n 
1 316 LEU n 
1 317 ALA n 
1 318 PRO n 
1 319 SER n 
1 320 THR n 
1 321 MET n 
1 322 LYS n 
1 323 ILE n 
1 324 LYS n 
1 325 ILE n 
1 326 ILE n 
1 327 ALA n 
1 328 PRO n 
1 329 PRO n 
1 330 GLU n 
1 331 ARG n 
1 332 LYS n 
1 333 TYR n 
1 334 SER n 
1 335 VAL n 
1 336 TRP n 
1 337 ILE n 
1 338 GLY n 
1 339 GLY n 
1 340 SER n 
1 341 ILE n 
1 342 LEU n 
1 343 ALA n 
1 344 SER n 
1 345 LEU n 
1 346 SER n 
1 347 THR n 
1 348 PHE n 
1 349 GLN n 
1 350 GLN n 
1 351 MET n 
1 352 TRP n 
1 353 ILE n 
1 354 SER n 
1 355 LYS n 
1 356 GLN n 
1 357 GLU n 
1 358 TYR n 
1 359 ASP n 
1 360 GLU n 
1 361 ALA n 
1 362 GLY n 
1 363 PRO n 
1 364 SER n 
1 365 ILE n 
1 366 VAL n 
1 367 HIS n 
1 368 ARG n 
1 369 LYS n 
1 370 CYS n 
2 1   ALA n 
2 2   GLN n 
2 3   MET n 
2 4   ALA n 
2 5   ASP n 
2 6   PHE n 
2 7   GLY n 
2 8   ALA n 
2 9   ALA n 
2 10  ALA n 
2 11  GLN n 
2 12  TYR n 
2 13  LEU n 
2 14  ARG n 
2 15  LYS n 
2 16  SER n 
2 17  GLU n 
2 18  LYS n 
2 19  GLU n 
2 20  ARG n 
2 21  LEU n 
2 22  GLU n 
2 23  ALA n 
2 24  GLN n 
2 25  THR n 
2 26  ARG n 
2 27  PRO n 
2 28  PHE n 
2 29  ASP n 
2 30  ILE n 
2 31  ARG n 
2 32  THR n 
2 33  GLU n 
2 34  CYS n 
2 35  PHE n 
2 36  VAL n 
2 37  PRO n 
2 38  ASP n 
2 39  ASP n 
2 40  LYS n 
2 41  GLU n 
2 42  GLU n 
2 43  TYR n 
2 44  VAL n 
2 45  LYS n 
2 46  ALA n 
2 47  LYS n 
2 48  VAL n 
2 49  VAL n 
2 50  SER n 
2 51  ARG n 
2 52  GLU n 
2 53  GLY n 
2 54  GLY n 
2 55  LYS n 
2 56  VAL n 
2 57  THR n 
2 58  ALA n 
2 59  GLU n 
2 60  THR n 
2 61  GLU n 
2 62  ASN n 
2 63  GLY n 
2 64  LYS n 
2 65  THR n 
2 66  VAL n 
2 67  THR n 
2 68  ILE n 
2 69  LYS n 
2 70  GLU n 
2 71  ASP n 
2 72  GLN n 
2 73  VAL n 
2 74  MET n 
2 75  GLN n 
2 76  GLN n 
2 77  ASN n 
2 78  PRO n 
2 79  PRO n 
2 80  LYS n 
2 81  PHE n 
2 82  ASP n 
2 83  LYS n 
2 84  ILE n 
2 85  GLU n 
2 86  ASP n 
2 87  MET n 
2 88  ALA n 
2 89  MET n 
2 90  LEU n 
2 91  THR n 
2 92  PHE n 
2 93  LEU n 
2 94  HIS n 
2 95  GLU n 
2 96  PRO n 
2 97  ALA n 
2 98  VAL n 
2 99  LEU n 
2 100 TYR n 
2 101 ASN n 
2 102 LEU n 
2 103 LYS n 
2 104 GLU n 
2 105 ARG n 
2 106 TYR n 
2 107 ALA n 
2 108 ALA n 
2 109 TRP n 
2 110 MET n 
2 111 ILE n 
2 112 TYR n 
2 113 THR n 
2 114 TYR n 
2 115 SER n 
2 116 GLY n 
2 117 LEU n 
2 118 PHE n 
2 119 CYS n 
2 120 VAL n 
2 121 THR n 
2 122 VAL n 
2 123 ASN n 
2 124 PRO n 
2 125 TYR n 
2 126 LYS n 
2 127 TRP n 
2 128 LEU n 
2 129 PRO n 
2 130 VAL n 
2 131 TYR n 
2 132 ASN n 
2 133 ALA n 
2 134 GLU n 
2 135 VAL n 
2 136 VAL n 
2 137 ALA n 
2 138 ALA n 
2 139 TYR n 
2 140 ARG n 
2 141 GLY n 
2 142 LYS n 
2 143 LYS n 
2 144 ARG n 
2 145 SER n 
2 146 GLU n 
2 147 ALA n 
2 148 PRO n 
2 149 PRO n 
2 150 HIS n 
2 151 ILE n 
2 152 PHE n 
2 153 SER n 
2 154 ILE n 
2 155 SER n 
2 156 ASP n 
2 157 ASN n 
2 158 ALA n 
2 159 TYR n 
2 160 GLN n 
2 161 TYR n 
2 162 MET n 
2 163 LEU n 
2 164 THR n 
2 165 ASP n 
2 166 ARG n 
2 167 GLU n 
2 168 ASN n 
2 169 GLN n 
2 170 SER n 
2 171 ILE n 
2 172 LEU n 
2 173 ILE n 
2 174 THR n 
2 175 GLY n 
2 176 GLU n 
2 177 SER n 
2 178 GLY n 
2 179 ALA n 
2 180 GLY n 
2 181 LYS n 
2 182 THR n 
2 183 VAL n 
2 184 ASN n 
2 185 THR n 
2 186 LYS n 
2 187 ARG n 
2 188 VAL n 
2 189 ILE n 
2 190 GLN n 
2 191 TYR n 
2 192 PHE n 
2 193 ALA n 
2 194 SER n 
2 195 ILE n 
2 196 ALA n 
2 197 ALA n 
2 198 ILE n 
2 199 GLY n 
2 200 ASP n 
2 201 ARG n 
2 202 SER n 
2 203 LYS n 
2 204 LYS n 
2 205 GLU n 
2 206 ASN n 
2 207 PRO n 
2 208 ASN n 
2 209 ALA n 
2 210 ASN n 
2 211 LYS n 
2 212 GLY n 
2 213 THR n 
2 214 LEU n 
2 215 GLU n 
2 216 ASP n 
2 217 GLN n 
2 218 ILE n 
2 219 ILE n 
2 220 GLN n 
2 221 ALA n 
2 222 ASN n 
2 223 PRO n 
2 224 ALA n 
2 225 LEU n 
2 226 GLU n 
2 227 ALA n 
2 228 PHE n 
2 229 GLY n 
2 230 ASN n 
2 231 ALA n 
2 232 LYS n 
2 233 THR n 
2 234 VAL n 
2 235 ARG n 
2 236 ASN n 
2 237 ASP n 
2 238 ASN n 
2 239 SER n 
2 240 SER n 
2 241 ARG n 
2 242 PHE n 
2 243 GLY n 
2 244 LYS n 
2 245 PHE n 
2 246 ILE n 
2 247 ARG n 
2 248 ILE n 
2 249 HIS n 
2 250 PHE n 
2 251 GLY n 
2 252 ALA n 
2 253 THR n 
2 254 GLY n 
2 255 LYS n 
2 256 LEU n 
2 257 ALA n 
2 258 SER n 
2 259 ALA n 
2 260 ASP n 
2 261 ILE n 
2 262 GLU n 
2 263 THR n 
2 264 TYR n 
2 265 LEU n 
2 266 LEU n 
2 267 GLU n 
2 268 LYS n 
2 269 SER n 
2 270 ARG n 
2 271 VAL n 
2 272 ILE n 
2 273 PHE n 
2 274 GLN n 
2 275 LEU n 
2 276 LYS n 
2 277 ALA n 
2 278 GLU n 
2 279 ARG n 
2 280 ASN n 
2 281 TYR n 
2 282 HIS n 
2 283 ILE n 
2 284 PHE n 
2 285 TYR n 
2 286 GLN n 
2 287 ILE n 
2 288 LEU n 
2 289 SER n 
2 290 ASN n 
2 291 LYS n 
2 292 LYS n 
2 293 PRO n 
2 294 GLU n 
2 295 LEU n 
2 296 LEU n 
2 297 ASP n 
2 298 MET n 
2 299 LEU n 
2 300 LEU n 
2 301 VAL n 
2 302 THR n 
2 303 ASN n 
2 304 ASN n 
2 305 PRO n 
2 306 TYR n 
2 307 ASP n 
2 308 TYR n 
2 309 ALA n 
2 310 PHE n 
2 311 VAL n 
2 312 SER n 
2 313 GLN n 
2 314 GLY n 
2 315 GLU n 
2 316 VAL n 
2 317 SER n 
2 318 VAL n 
2 319 ALA n 
2 320 SER n 
2 321 ILE n 
2 322 ASP n 
2 323 ASP n 
2 324 SER n 
2 325 GLU n 
2 326 GLU n 
2 327 LEU n 
2 328 LEU n 
2 329 ALA n 
2 330 THR n 
2 331 ASP n 
2 332 SER n 
2 333 ALA n 
2 334 PHE n 
2 335 ASP n 
2 336 VAL n 
2 337 LEU n 
2 338 SER n 
2 339 PHE n 
2 340 THR n 
2 341 ALA n 
2 342 GLU n 
2 343 GLU n 
2 344 LYS n 
2 345 ALA n 
2 346 GLY n 
2 347 VAL n 
2 348 TYR n 
2 349 LYS n 
2 350 LEU n 
2 351 THR n 
2 352 GLY n 
2 353 ALA n 
2 354 ILE n 
2 355 MET n 
2 356 HIS n 
2 357 TYR n 
2 358 GLY n 
2 359 ASN n 
2 360 MET n 
2 361 LYS n 
2 362 PHE n 
2 363 LYS n 
2 364 GLN n 
2 365 LYS n 
2 366 GLN n 
2 367 ARG n 
2 368 GLU n 
2 369 GLU n 
2 370 GLN n 
2 371 ALA n 
2 372 GLU n 
2 373 PRO n 
2 374 ASP n 
2 375 GLY n 
2 376 THR n 
2 377 GLU n 
2 378 ASP n 
2 379 ALA n 
2 380 ASP n 
2 381 LYS n 
2 382 SER n 
2 383 ALA n 
2 384 TYR n 
2 385 LEU n 
2 386 MET n 
2 387 GLY n 
2 388 LEU n 
2 389 ASN n 
2 390 SER n 
2 391 ALA n 
2 392 ASP n 
2 393 LEU n 
2 394 LEU n 
2 395 LYS n 
2 396 GLY n 
2 397 LEU n 
2 398 CYS n 
2 399 HIS n 
2 400 PRO n 
2 401 GLN n 
2 402 VAL n 
2 403 LYS n 
2 404 VAL n 
2 405 GLY n 
2 406 ASN n 
2 407 GLU n 
2 408 TYR n 
2 409 VAL n 
2 410 THR n 
2 411 LYS n 
2 412 GLY n 
2 413 GLN n 
2 414 SER n 
2 415 VAL n 
2 416 GLN n 
2 417 GLN n 
2 418 VAL n 
2 419 TYR n 
2 420 TYR n 
2 421 SER n 
2 422 ILE n 
2 423 GLY n 
2 424 ALA n 
2 425 LEU n 
2 426 ALA n 
2 427 LYS n 
2 428 SER n 
2 429 VAL n 
2 430 TYR n 
2 431 GLU n 
2 432 LYS n 
2 433 MET n 
2 434 PHE n 
2 435 ASN n 
2 436 TRP n 
2 437 MET n 
2 438 VAL n 
2 439 THR n 
2 440 ARG n 
2 441 ILE n 
2 442 ASN n 
2 443 ALA n 
2 444 THR n 
2 445 LEU n 
2 446 GLU n 
2 447 THR n 
2 448 LYS n 
2 449 GLN n 
2 450 PRO n 
2 451 ARG n 
2 452 GLN n 
2 453 TYR n 
2 454 PHE n 
2 455 ILE n 
2 456 GLY n 
2 457 VAL n 
2 458 LEU n 
2 459 ASP n 
2 460 ILE n 
2 461 ALA n 
2 462 GLY n 
2 463 PHE n 
2 464 GLU n 
2 465 ILE n 
2 466 PHE n 
2 467 ASP n 
2 468 PHE n 
2 469 ASN n 
2 470 SER n 
2 471 PHE n 
2 472 GLU n 
2 473 GLN n 
2 474 LEU n 
2 475 CYS n 
2 476 ILE n 
2 477 ASN n 
2 478 PHE n 
2 479 THR n 
2 480 ASN n 
2 481 GLU n 
2 482 LYS n 
2 483 LEU n 
2 484 GLN n 
2 485 GLN n 
2 486 PHE n 
2 487 PHE n 
2 488 ASN n 
2 489 HIS n 
2 490 HIS n 
2 491 MET n 
2 492 PHE n 
2 493 VAL n 
2 494 LEU n 
2 495 GLU n 
2 496 GLN n 
2 497 GLU n 
2 498 GLU n 
2 499 TYR n 
2 500 LYS n 
2 501 LYS n 
2 502 GLU n 
2 503 GLY n 
2 504 ILE n 
2 505 GLU n 
2 506 TRP n 
2 507 GLU n 
2 508 PHE n 
2 509 ILE n 
2 510 ASP n 
2 511 PHE n 
2 512 GLY n 
2 513 MET n 
2 514 ASP n 
2 515 LEU n 
2 516 GLN n 
2 517 ALA n 
2 518 CYS n 
2 519 ILE n 
2 520 ASP n 
2 521 LEU n 
2 522 ILE n 
2 523 GLU n 
2 524 LYS n 
2 525 PRO n 
2 526 MET n 
2 527 GLY n 
2 528 ILE n 
2 529 MET n 
2 530 SER n 
2 531 ILE n 
2 532 LEU n 
2 533 GLU n 
2 534 GLU n 
2 535 GLU n 
2 536 CYS n 
2 537 MET n 
2 538 PHE n 
2 539 PRO n 
2 540 LYS n 
2 541 ALA n 
2 542 SER n 
2 543 ASP n 
2 544 MET n 
2 545 THR n 
2 546 PHE n 
2 547 LYS n 
2 548 ALA n 
2 549 LYS n 
2 550 LEU n 
2 551 TYR n 
2 552 ASP n 
2 553 ASN n 
2 554 HIS n 
2 555 LEU n 
2 556 GLY n 
2 557 LYS n 
2 558 SER n 
2 559 ASN n 
2 560 ASN n 
2 561 PHE n 
2 562 GLN n 
2 563 LYS n 
2 564 PRO n 
2 565 ARG n 
2 566 ASN n 
2 567 VAL n 
2 568 LYS n 
2 569 GLY n 
2 570 LYS n 
2 571 GLN n 
2 572 GLU n 
2 573 ALA n 
2 574 HIS n 
2 575 PHE n 
2 576 SER n 
2 577 LEU n 
2 578 VAL n 
2 579 HIS n 
2 580 TYR n 
2 581 ALA n 
2 582 GLY n 
2 583 THR n 
2 584 VAL n 
2 585 ASP n 
2 586 TYR n 
2 587 ASN n 
2 588 ILE n 
2 589 MET n 
2 590 GLY n 
2 591 TRP n 
2 592 LEU n 
2 593 GLU n 
2 594 LYS n 
2 595 ASN n 
2 596 LYS n 
2 597 ASP n 
2 598 PRO n 
2 599 LEU n 
2 600 ASN n 
2 601 GLU n 
2 602 THR n 
2 603 VAL n 
2 604 VAL n 
2 605 GLY n 
2 606 LEU n 
2 607 TYR n 
2 608 GLN n 
2 609 LYS n 
2 610 SER n 
2 611 SER n 
2 612 LEU n 
2 613 LYS n 
2 614 LEU n 
2 615 MET n 
2 616 ALA n 
2 617 THR n 
2 618 LEU n 
2 619 PHE n 
2 620 SER n 
2 621 THR n 
2 622 TYR n 
2 623 ALA n 
2 624 SER n 
2 625 ALA n 
2 626 ASP n 
2 627 THR n 
2 628 GLY n 
2 629 ASP n 
2 630 SER n 
2 631 GLY n 
2 632 LYS n 
2 633 GLY n 
2 634 LYS n 
2 635 GLY n 
2 636 GLY n 
2 637 LYS n 
2 638 LYS n 
2 639 LYS n 
2 640 GLY n 
2 641 SER n 
2 642 SER n 
2 643 PHE n 
2 644 GLN n 
2 645 THR n 
2 646 VAL n 
2 647 SER n 
2 648 ALA n 
2 649 LEU n 
2 650 HIS n 
2 651 ARG n 
2 652 GLU n 
2 653 ASN n 
2 654 LEU n 
2 655 ASN n 
2 656 LYS n 
2 657 LEU n 
2 658 MET n 
2 659 THR n 
2 660 ASN n 
2 661 LEU n 
2 662 LYS n 
2 663 THR n 
2 664 THR n 
2 665 HIS n 
2 666 PRO n 
2 667 HIS n 
2 668 PHE n 
2 669 VAL n 
2 670 ARG n 
2 671 CYS n 
2 672 ILE n 
2 673 ILE n 
2 674 PRO n 
2 675 ASN n 
2 676 GLU n 
2 677 ARG n 
2 678 LYS n 
2 679 ALA n 
2 680 PRO n 
2 681 GLY n 
2 682 VAL n 
2 683 MET n 
2 684 ASP n 
2 685 ASN n 
2 686 PRO n 
2 687 LEU n 
2 688 VAL n 
2 689 MET n 
2 690 HIS n 
2 691 GLN n 
2 692 LEU n 
2 693 ARG n 
2 694 CYS n 
2 695 ASN n 
2 696 GLY n 
2 697 VAL n 
2 698 LEU n 
2 699 GLU n 
2 700 GLY n 
2 701 ILE n 
2 702 ARG n 
2 703 ILE n 
2 704 CYS n 
2 705 ARG n 
2 706 LYS n 
2 707 GLY n 
2 708 PHE n 
2 709 PRO n 
2 710 ASN n 
2 711 ARG n 
2 712 ILE n 
2 713 LEU n 
2 714 TYR n 
2 715 GLY n 
2 716 ASP n 
2 717 PHE n 
2 718 ARG n 
2 719 GLN n 
2 720 ARG n 
2 721 TYR n 
2 722 ARG n 
2 723 ILE n 
2 724 LEU n 
2 725 ASN n 
2 726 PRO n 
2 727 ALA n 
2 728 ALA n 
2 729 ILE n 
2 730 PRO n 
2 731 GLU n 
2 732 GLY n 
2 733 GLN n 
2 734 PHE n 
2 735 ILE n 
2 736 ASP n 
2 737 SER n 
2 738 ARG n 
2 739 LYS n 
2 740 GLY n 
2 741 ALA n 
2 742 GLU n 
2 743 LYS n 
2 744 LEU n 
2 745 LEU n 
2 746 GLY n 
2 747 SER n 
2 748 LEU n 
2 749 ASP n 
2 750 ILE n 
2 751 ASP n 
2 752 HIS n 
2 753 ASN n 
2 754 GLN n 
2 755 TYR n 
2 756 LYS n 
2 757 PHE n 
2 758 GLY n 
2 759 HIS n 
2 760 THR n 
2 761 LYS n 
2 762 VAL n 
2 763 PHE n 
2 764 PHE n 
2 765 LYS n 
2 766 ALA n 
2 767 GLY n 
2 768 LEU n 
2 769 LEU n 
2 770 GLY n 
2 771 LEU n 
2 772 LEU n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 370 'house mouse' 'Mus musculus' 10090 ? ? C57BL/6JGpt ? ? ? ? 'Myh6em1Cin(R404Q)' ? ? ? ? ? ? ? ? ? 
2 1 sample 1 772 'house mouse' 'Mus musculus' 10090 ? ? C57BL/6JGpt ? ? ? ? 'Myh6em1Cin(R404Q)' ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ADP non-polymer         n "ADENOSINE-5'-DIPHOSPHATE" ? 'C10 H15 N5 O10 P2' 427.201 
ALA 'L-peptide linking' y ALANINE                    ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                   ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                 ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'            ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                   ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                  ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'            ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                    ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                  ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                 ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                    ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                     ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                 ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE              ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                    ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                     ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                  ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                 ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                   ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                     ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   THR 1   7   7   THR THR J . n 
A 1 2   THR 2   8   8   THR THR J . n 
A 1 3   ALA 3   9   9   ALA ALA J . n 
A 1 4   LEU 4   10  10  LEU LEU J . n 
A 1 5   VAL 5   11  11  VAL VAL J . n 
A 1 6   CYS 6   12  12  CYS CYS J . n 
A 1 7   ASP 7   13  13  ASP ASP J . n 
A 1 8   ASN 8   14  14  ASN ASN J . n 
A 1 9   GLY 9   15  15  GLY GLY J . n 
A 1 10  SER 10  16  16  SER SER J . n 
A 1 11  GLY 11  17  17  GLY GLY J . n 
A 1 12  LEU 12  18  18  LEU LEU J . n 
A 1 13  VAL 13  19  19  VAL VAL J . n 
A 1 14  LYS 14  20  20  LYS LYS J . n 
A 1 15  ALA 15  21  21  ALA ALA J . n 
A 1 16  GLY 16  22  22  GLY GLY J . n 
A 1 17  PHE 17  23  23  PHE PHE J . n 
A 1 18  ALA 18  24  24  ALA ALA J . n 
A 1 19  GLY 19  25  25  GLY GLY J . n 
A 1 20  ASP 20  26  26  ASP ASP J . n 
A 1 21  ASP 21  27  27  ASP ASP J . n 
A 1 22  ALA 22  28  28  ALA ALA J . n 
A 1 23  PRO 23  29  29  PRO PRO J . n 
A 1 24  ARG 24  30  30  ARG ARG J . n 
A 1 25  ALA 25  31  31  ALA ALA J . n 
A 1 26  VAL 26  32  32  VAL VAL J . n 
A 1 27  PHE 27  33  33  PHE PHE J . n 
A 1 28  PRO 28  34  34  PRO PRO J . n 
A 1 29  SER 29  35  35  SER SER J . n 
A 1 30  ILE 30  36  36  ILE ILE J . n 
A 1 31  VAL 31  37  37  VAL VAL J . n 
A 1 32  GLY 32  38  38  GLY GLY J . n 
A 1 33  ARG 33  39  39  ARG ARG J . n 
A 1 34  PRO 34  40  40  PRO PRO J . n 
A 1 35  ARG 35  41  41  ARG ARG J . n 
A 1 36  HIS 36  42  42  HIS HIS J . n 
A 1 37  GLN 37  43  43  GLN GLN J . n 
A 1 38  GLY 38  44  44  GLY GLY J . n 
A 1 39  VAL 39  45  45  VAL VAL J . n 
A 1 40  MET 40  46  46  MET MET J . n 
A 1 41  VAL 41  47  47  VAL VAL J . n 
A 1 42  GLY 42  48  48  GLY GLY J . n 
A 1 43  MET 43  49  49  MET MET J . n 
A 1 44  GLY 44  50  50  GLY GLY J . n 
A 1 45  GLN 45  51  51  GLN GLN J . n 
A 1 46  LYS 46  52  52  LYS LYS J . n 
A 1 47  ASP 47  53  53  ASP ASP J . n 
A 1 48  SER 48  54  54  SER SER J . n 
A 1 49  TYR 49  55  55  TYR TYR J . n 
A 1 50  VAL 50  56  56  VAL VAL J . n 
A 1 51  GLY 51  57  57  GLY GLY J . n 
A 1 52  ASP 52  58  58  ASP ASP J . n 
A 1 53  GLU 53  59  59  GLU GLU J . n 
A 1 54  ALA 54  60  60  ALA ALA J . n 
A 1 55  GLN 55  61  61  GLN GLN J . n 
A 1 56  SER 56  62  62  SER SER J . n 
A 1 57  LYS 57  63  63  LYS LYS J . n 
A 1 58  ARG 58  64  64  ARG ARG J . n 
A 1 59  GLY 59  65  65  GLY GLY J . n 
A 1 60  ILE 60  66  66  ILE ILE J . n 
A 1 61  LEU 61  67  67  LEU LEU J . n 
A 1 62  THR 62  68  68  THR THR J . n 
A 1 63  LEU 63  69  69  LEU LEU J . n 
A 1 64  LYS 64  70  70  LYS LYS J . n 
A 1 65  TYR 65  71  71  TYR TYR J . n 
A 1 66  PRO 66  72  72  PRO PRO J . n 
A 1 67  ILE 67  73  73  ILE ILE J . n 
A 1 68  GLU 68  74  74  GLU GLU J . n 
A 1 69  HIS 69  75  75  HIS HIS J . n 
A 1 70  GLY 70  76  76  GLY GLY J . n 
A 1 71  ILE 71  77  77  ILE ILE J . n 
A 1 72  ILE 72  78  78  ILE ILE J . n 
A 1 73  THR 73  79  79  THR THR J . n 
A 1 74  ASN 74  80  80  ASN ASN J . n 
A 1 75  TRP 75  81  81  TRP TRP J . n 
A 1 76  ASP 76  82  82  ASP ASP J . n 
A 1 77  ASP 77  83  83  ASP ASP J . n 
A 1 78  MET 78  84  84  MET MET J . n 
A 1 79  GLU 79  85  85  GLU GLU J . n 
A 1 80  LYS 80  86  86  LYS LYS J . n 
A 1 81  ILE 81  87  87  ILE ILE J . n 
A 1 82  TRP 82  88  88  TRP TRP J . n 
A 1 83  HIS 83  89  89  HIS HIS J . n 
A 1 84  HIS 84  90  90  HIS HIS J . n 
A 1 85  THR 85  91  91  THR THR J . n 
A 1 86  PHE 86  92  92  PHE PHE J . n 
A 1 87  TYR 87  93  93  TYR TYR J . n 
A 1 88  ASN 88  94  94  ASN ASN J . n 
A 1 89  GLU 89  95  95  GLU GLU J . n 
A 1 90  LEU 90  96  96  LEU LEU J . n 
A 1 91  ARG 91  97  97  ARG ARG J . n 
A 1 92  VAL 92  98  98  VAL VAL J . n 
A 1 93  ALA 93  99  99  ALA ALA J . n 
A 1 94  PRO 94  100 100 PRO PRO J . n 
A 1 95  GLU 95  101 101 GLU GLU J . n 
A 1 96  GLU 96  102 102 GLU GLU J . n 
A 1 97  HIS 97  103 103 HIS HIS J . n 
A 1 98  PRO 98  104 104 PRO PRO J . n 
A 1 99  THR 99  105 105 THR THR J . n 
A 1 100 LEU 100 106 106 LEU LEU J . n 
A 1 101 LEU 101 107 107 LEU LEU J . n 
A 1 102 THR 102 108 108 THR THR J . n 
A 1 103 GLU 103 109 109 GLU GLU J . n 
A 1 104 ALA 104 110 110 ALA ALA J . n 
A 1 105 PRO 105 111 111 PRO PRO J . n 
A 1 106 LEU 106 112 112 LEU LEU J . n 
A 1 107 ASN 107 113 113 ASN ASN J . n 
A 1 108 PRO 108 114 114 PRO PRO J . n 
A 1 109 LYS 109 115 115 LYS LYS J . n 
A 1 110 ALA 110 116 116 ALA ALA J . n 
A 1 111 ASN 111 117 117 ASN ASN J . n 
A 1 112 ARG 112 118 118 ARG ARG J . n 
A 1 113 GLU 113 119 119 GLU GLU J . n 
A 1 114 LYS 114 120 120 LYS LYS J . n 
A 1 115 MET 115 121 121 MET MET J . n 
A 1 116 THR 116 122 122 THR THR J . n 
A 1 117 GLN 117 123 123 GLN GLN J . n 
A 1 118 ILE 118 124 124 ILE ILE J . n 
A 1 119 MET 119 125 125 MET MET J . n 
A 1 120 PHE 120 126 126 PHE PHE J . n 
A 1 121 GLU 121 127 127 GLU GLU J . n 
A 1 122 THR 122 128 128 THR THR J . n 
A 1 123 PHE 123 129 129 PHE PHE J . n 
A 1 124 ASN 124 130 130 ASN ASN J . n 
A 1 125 VAL 125 131 131 VAL VAL J . n 
A 1 126 PRO 126 132 132 PRO PRO J . n 
A 1 127 ALA 127 133 133 ALA ALA J . n 
A 1 128 MET 128 134 134 MET MET J . n 
A 1 129 TYR 129 135 135 TYR TYR J . n 
A 1 130 VAL 130 136 136 VAL VAL J . n 
A 1 131 ALA 131 137 137 ALA ALA J . n 
A 1 132 ILE 132 138 138 ILE ILE J . n 
A 1 133 GLN 133 139 139 GLN GLN J . n 
A 1 134 ALA 134 140 140 ALA ALA J . n 
A 1 135 VAL 135 141 141 VAL VAL J . n 
A 1 136 LEU 136 142 142 LEU LEU J . n 
A 1 137 SER 137 143 143 SER SER J . n 
A 1 138 LEU 138 144 144 LEU LEU J . n 
A 1 139 TYR 139 145 145 TYR TYR J . n 
A 1 140 ALA 140 146 146 ALA ALA J . n 
A 1 141 SER 141 147 147 SER SER J . n 
A 1 142 GLY 142 148 148 GLY GLY J . n 
A 1 143 ARG 143 149 149 ARG ARG J . n 
A 1 144 THR 144 150 150 THR THR J . n 
A 1 145 THR 145 151 151 THR THR J . n 
A 1 146 GLY 146 152 152 GLY GLY J . n 
A 1 147 ILE 147 153 153 ILE ILE J . n 
A 1 148 VAL 148 154 154 VAL VAL J . n 
A 1 149 LEU 149 155 155 LEU LEU J . n 
A 1 150 ASP 150 156 156 ASP ASP J . n 
A 1 151 SER 151 157 157 SER SER J . n 
A 1 152 GLY 152 158 158 GLY GLY J . n 
A 1 153 ASP 153 159 159 ASP ASP J . n 
A 1 154 GLY 154 160 160 GLY GLY J . n 
A 1 155 VAL 155 161 161 VAL VAL J . n 
A 1 156 THR 156 162 162 THR THR J . n 
A 1 157 HIS 157 163 163 HIS HIS J . n 
A 1 158 ASN 158 164 164 ASN ASN J . n 
A 1 159 VAL 159 165 165 VAL VAL J . n 
A 1 160 PRO 160 166 166 PRO PRO J . n 
A 1 161 ILE 161 167 167 ILE ILE J . n 
A 1 162 TYR 162 168 168 TYR TYR J . n 
A 1 163 GLU 163 169 169 GLU GLU J . n 
A 1 164 GLY 164 170 170 GLY GLY J . n 
A 1 165 TYR 165 171 171 TYR TYR J . n 
A 1 166 ALA 166 172 172 ALA ALA J . n 
A 1 167 LEU 167 173 173 LEU LEU J . n 
A 1 168 PRO 168 174 174 PRO PRO J . n 
A 1 169 HIS 169 175 175 HIS HIS J . n 
A 1 170 ALA 170 176 176 ALA ALA J . n 
A 1 171 ILE 171 177 177 ILE ILE J . n 
A 1 172 MET 172 178 178 MET MET J . n 
A 1 173 ARG 173 179 179 ARG ARG J . n 
A 1 174 LEU 174 180 180 LEU LEU J . n 
A 1 175 ASP 175 181 181 ASP ASP J . n 
A 1 176 LEU 176 182 182 LEU LEU J . n 
A 1 177 ALA 177 183 183 ALA ALA J . n 
A 1 178 GLY 178 184 184 GLY GLY J . n 
A 1 179 ARG 179 185 185 ARG ARG J . n 
A 1 180 ASP 180 186 186 ASP ASP J . n 
A 1 181 LEU 181 187 187 LEU LEU J . n 
A 1 182 THR 182 188 188 THR THR J . n 
A 1 183 ASP 183 189 189 ASP ASP J . n 
A 1 184 TYR 184 190 190 TYR TYR J . n 
A 1 185 LEU 185 191 191 LEU LEU J . n 
A 1 186 MET 186 192 192 MET MET J . n 
A 1 187 LYS 187 193 193 LYS LYS J . n 
A 1 188 ILE 188 194 194 ILE ILE J . n 
A 1 189 LEU 189 195 195 LEU LEU J . n 
A 1 190 THR 190 196 196 THR THR J . n 
A 1 191 GLU 191 197 197 GLU GLU J . n 
A 1 192 ARG 192 198 198 ARG ARG J . n 
A 1 193 GLY 193 199 199 GLY GLY J . n 
A 1 194 TYR 194 200 200 TYR TYR J . n 
A 1 195 SER 195 201 201 SER SER J . n 
A 1 196 PHE 196 202 202 PHE PHE J . n 
A 1 197 VAL 197 203 203 VAL VAL J . n 
A 1 198 THR 198 204 204 THR THR J . n 
A 1 199 THR 199 205 205 THR THR J . n 
A 1 200 ALA 200 206 206 ALA ALA J . n 
A 1 201 GLU 201 207 207 GLU GLU J . n 
A 1 202 ARG 202 208 208 ARG ARG J . n 
A 1 203 GLU 203 209 209 GLU GLU J . n 
A 1 204 ILE 204 210 210 ILE ILE J . n 
A 1 205 VAL 205 211 211 VAL VAL J . n 
A 1 206 ARG 206 212 212 ARG ARG J . n 
A 1 207 ASP 207 213 213 ASP ASP J . n 
A 1 208 ILE 208 214 214 ILE ILE J . n 
A 1 209 LYS 209 215 215 LYS LYS J . n 
A 1 210 GLU 210 216 216 GLU GLU J . n 
A 1 211 LYS 211 217 217 LYS LYS J . n 
A 1 212 LEU 212 218 218 LEU LEU J . n 
A 1 213 CYS 213 219 219 CYS CYS J . n 
A 1 214 TYR 214 220 220 TYR TYR J . n 
A 1 215 VAL 215 221 221 VAL VAL J . n 
A 1 216 ALA 216 222 222 ALA ALA J . n 
A 1 217 LEU 217 223 223 LEU LEU J . n 
A 1 218 ASP 218 224 224 ASP ASP J . n 
A 1 219 PHE 219 225 225 PHE PHE J . n 
A 1 220 GLU 220 226 226 GLU GLU J . n 
A 1 221 ASN 221 227 227 ASN ASN J . n 
A 1 222 GLU 222 228 228 GLU GLU J . n 
A 1 223 MET 223 229 229 MET MET J . n 
A 1 224 ALA 224 230 230 ALA ALA J . n 
A 1 225 THR 225 231 231 THR THR J . n 
A 1 226 ALA 226 232 232 ALA ALA J . n 
A 1 227 ALA 227 233 233 ALA ALA J . n 
A 1 228 SER 228 234 234 SER SER J . n 
A 1 229 SER 229 235 235 SER SER J . n 
A 1 230 SER 230 236 236 SER SER J . n 
A 1 231 SER 231 237 237 SER SER J . n 
A 1 232 LEU 232 238 238 LEU LEU J . n 
A 1 233 GLU 233 239 239 GLU GLU J . n 
A 1 234 LYS 234 240 240 LYS LYS J . n 
A 1 235 SER 235 241 241 SER SER J . n 
A 1 236 TYR 236 242 242 TYR TYR J . n 
A 1 237 GLU 237 243 243 GLU GLU J . n 
A 1 238 LEU 238 244 244 LEU LEU J . n 
A 1 239 PRO 239 245 245 PRO PRO J . n 
A 1 240 ASP 240 246 246 ASP ASP J . n 
A 1 241 GLY 241 247 247 GLY GLY J . n 
A 1 242 GLN 242 248 248 GLN GLN J . n 
A 1 243 VAL 243 249 249 VAL VAL J . n 
A 1 244 ILE 244 250 250 ILE ILE J . n 
A 1 245 THR 245 251 251 THR THR J . n 
A 1 246 ILE 246 252 252 ILE ILE J . n 
A 1 247 GLY 247 253 253 GLY GLY J . n 
A 1 248 ASN 248 254 254 ASN ASN J . n 
A 1 249 GLU 249 255 255 GLU GLU J . n 
A 1 250 ARG 250 256 256 ARG ARG J . n 
A 1 251 PHE 251 257 257 PHE PHE J . n 
A 1 252 ARG 252 258 258 ARG ARG J . n 
A 1 253 CYS 253 259 259 CYS CYS J . n 
A 1 254 PRO 254 260 260 PRO PRO J . n 
A 1 255 GLU 255 261 261 GLU GLU J . n 
A 1 256 THR 256 262 262 THR THR J . n 
A 1 257 LEU 257 263 263 LEU LEU J . n 
A 1 258 PHE 258 264 264 PHE PHE J . n 
A 1 259 GLN 259 265 265 GLN GLN J . n 
A 1 260 PRO 260 266 266 PRO PRO J . n 
A 1 261 SER 261 267 267 SER SER J . n 
A 1 262 PHE 262 268 268 PHE PHE J . n 
A 1 263 ILE 263 269 269 ILE ILE J . n 
A 1 264 GLY 264 270 270 GLY GLY J . n 
A 1 265 MET 265 271 271 MET MET J . n 
A 1 266 GLU 266 272 272 GLU GLU J . n 
A 1 267 SER 267 273 273 SER SER J . n 
A 1 268 ALA 268 274 274 ALA ALA J . n 
A 1 269 GLY 269 275 275 GLY GLY J . n 
A 1 270 ILE 270 276 276 ILE ILE J . n 
A 1 271 HIS 271 277 277 HIS HIS J . n 
A 1 272 GLU 272 278 278 GLU GLU J . n 
A 1 273 THR 273 279 279 THR THR J . n 
A 1 274 THR 274 280 280 THR THR J . n 
A 1 275 TYR 275 281 281 TYR TYR J . n 
A 1 276 ASN 276 282 282 ASN ASN J . n 
A 1 277 SER 277 283 283 SER SER J . n 
A 1 278 ILE 278 284 284 ILE ILE J . n 
A 1 279 MET 279 285 285 MET MET J . n 
A 1 280 LYS 280 286 286 LYS LYS J . n 
A 1 281 CYS 281 287 287 CYS CYS J . n 
A 1 282 ASP 282 288 288 ASP ASP J . n 
A 1 283 ILE 283 289 289 ILE ILE J . n 
A 1 284 ASP 284 290 290 ASP ASP J . n 
A 1 285 ILE 285 291 291 ILE ILE J . n 
A 1 286 ARG 286 292 292 ARG ARG J . n 
A 1 287 LYS 287 293 293 LYS LYS J . n 
A 1 288 ASP 288 294 294 ASP ASP J . n 
A 1 289 LEU 289 295 295 LEU LEU J . n 
A 1 290 TYR 290 296 296 TYR TYR J . n 
A 1 291 ALA 291 297 297 ALA ALA J . n 
A 1 292 ASN 292 298 298 ASN ASN J . n 
A 1 293 ASN 293 299 299 ASN ASN J . n 
A 1 294 VAL 294 300 300 VAL VAL J . n 
A 1 295 LEU 295 301 301 LEU LEU J . n 
A 1 296 SER 296 302 302 SER SER J . n 
A 1 297 GLY 297 303 303 GLY GLY J . n 
A 1 298 GLY 298 304 304 GLY GLY J . n 
A 1 299 THR 299 305 305 THR THR J . n 
A 1 300 THR 300 306 306 THR THR J . n 
A 1 301 MET 301 307 307 MET MET J . n 
A 1 302 TYR 302 308 308 TYR TYR J . n 
A 1 303 PRO 303 309 309 PRO PRO J . n 
A 1 304 GLY 304 310 310 GLY GLY J . n 
A 1 305 ILE 305 311 311 ILE ILE J . n 
A 1 306 ALA 306 312 312 ALA ALA J . n 
A 1 307 ASP 307 313 313 ASP ASP J . n 
A 1 308 ARG 308 314 314 ARG ARG J . n 
A 1 309 MET 309 315 315 MET MET J . n 
A 1 310 GLN 310 316 316 GLN GLN J . n 
A 1 311 LYS 311 317 317 LYS LYS J . n 
A 1 312 GLU 312 318 318 GLU GLU J . n 
A 1 313 ILE 313 319 319 ILE ILE J . n 
A 1 314 THR 314 320 320 THR THR J . n 
A 1 315 ALA 315 321 321 ALA ALA J . n 
A 1 316 LEU 316 322 322 LEU LEU J . n 
A 1 317 ALA 317 323 323 ALA ALA J . n 
A 1 318 PRO 318 324 324 PRO PRO J . n 
A 1 319 SER 319 325 325 SER SER J . n 
A 1 320 THR 320 326 326 THR THR J . n 
A 1 321 MET 321 327 327 MET MET J . n 
A 1 322 LYS 322 328 328 LYS LYS J . n 
A 1 323 ILE 323 329 329 ILE ILE J . n 
A 1 324 LYS 324 330 330 LYS LYS J . n 
A 1 325 ILE 325 331 331 ILE ILE J . n 
A 1 326 ILE 326 332 332 ILE ILE J . n 
A 1 327 ALA 327 333 333 ALA ALA J . n 
A 1 328 PRO 328 334 334 PRO PRO J . n 
A 1 329 PRO 329 335 335 PRO PRO J . n 
A 1 330 GLU 330 336 336 GLU GLU J . n 
A 1 331 ARG 331 337 337 ARG ARG J . n 
A 1 332 LYS 332 338 338 LYS LYS J . n 
A 1 333 TYR 333 339 339 TYR TYR J . n 
A 1 334 SER 334 340 340 SER SER J . n 
A 1 335 VAL 335 341 341 VAL VAL J . n 
A 1 336 TRP 336 342 342 TRP TRP J . n 
A 1 337 ILE 337 343 343 ILE ILE J . n 
A 1 338 GLY 338 344 344 GLY GLY J . n 
A 1 339 GLY 339 345 345 GLY GLY J . n 
A 1 340 SER 340 346 346 SER SER J . n 
A 1 341 ILE 341 347 347 ILE ILE J . n 
A 1 342 LEU 342 348 348 LEU LEU J . n 
A 1 343 ALA 343 349 349 ALA ALA J . n 
A 1 344 SER 344 350 350 SER SER J . n 
A 1 345 LEU 345 351 351 LEU LEU J . n 
A 1 346 SER 346 352 352 SER SER J . n 
A 1 347 THR 347 353 353 THR THR J . n 
A 1 348 PHE 348 354 354 PHE PHE J . n 
A 1 349 GLN 349 355 355 GLN GLN J . n 
A 1 350 GLN 350 356 356 GLN GLN J . n 
A 1 351 MET 351 357 357 MET MET J . n 
A 1 352 TRP 352 358 358 TRP TRP J . n 
A 1 353 ILE 353 359 359 ILE ILE J . n 
A 1 354 SER 354 360 360 SER SER J . n 
A 1 355 LYS 355 361 361 LYS LYS J . n 
A 1 356 GLN 356 362 362 GLN GLN J . n 
A 1 357 GLU 357 363 363 GLU GLU J . n 
A 1 358 TYR 358 364 364 TYR TYR J . n 
A 1 359 ASP 359 365 365 ASP ASP J . n 
A 1 360 GLU 360 366 366 GLU GLU J . n 
A 1 361 ALA 361 367 367 ALA ALA J . n 
A 1 362 GLY 362 368 368 GLY GLY J . n 
A 1 363 PRO 363 369 369 PRO PRO J . n 
A 1 364 SER 364 370 370 SER SER J . n 
A 1 365 ILE 365 371 371 ILE ILE J . n 
A 1 366 VAL 366 372 372 VAL VAL J . n 
A 1 367 HIS 367 373 373 HIS HIS J . n 
A 1 368 ARG 368 374 374 ARG ARG J . n 
A 1 369 LYS 369 375 375 LYS LYS J . n 
A 1 370 CYS 370 376 376 CYS CYS J . n 
B 2 1   ALA 1   4   4   ALA ALA C . n 
B 2 2   GLN 2   5   5   GLN GLN C . n 
B 2 3   MET 3   6   6   MET MET C . n 
B 2 4   ALA 4   7   7   ALA ALA C . n 
B 2 5   ASP 5   8   8   ASP ASP C . n 
B 2 6   PHE 6   9   9   PHE PHE C . n 
B 2 7   GLY 7   10  10  GLY GLY C . n 
B 2 8   ALA 8   11  11  ALA ALA C . n 
B 2 9   ALA 9   12  12  ALA ALA C . n 
B 2 10  ALA 10  13  13  ALA ALA C . n 
B 2 11  GLN 11  14  14  GLN GLN C . n 
B 2 12  TYR 12  15  15  TYR TYR C . n 
B 2 13  LEU 13  16  16  LEU LEU C . n 
B 2 14  ARG 14  17  17  ARG ARG C . n 
B 2 15  LYS 15  18  18  LYS LYS C . n 
B 2 16  SER 16  19  19  SER SER C . n 
B 2 17  GLU 17  20  20  GLU GLU C . n 
B 2 18  LYS 18  21  21  LYS LYS C . n 
B 2 19  GLU 19  22  22  GLU GLU C . n 
B 2 20  ARG 20  23  23  ARG ARG C . n 
B 2 21  LEU 21  24  24  LEU LEU C . n 
B 2 22  GLU 22  25  25  GLU GLU C . n 
B 2 23  ALA 23  26  26  ALA ALA C . n 
B 2 24  GLN 24  27  27  GLN GLN C . n 
B 2 25  THR 25  28  28  THR THR C . n 
B 2 26  ARG 26  29  29  ARG ARG C . n 
B 2 27  PRO 27  30  30  PRO PRO C . n 
B 2 28  PHE 28  31  31  PHE PHE C . n 
B 2 29  ASP 29  32  32  ASP ASP C . n 
B 2 30  ILE 30  33  33  ILE ILE C . n 
B 2 31  ARG 31  34  34  ARG ARG C . n 
B 2 32  THR 32  35  35  THR THR C . n 
B 2 33  GLU 33  36  36  GLU GLU C . n 
B 2 34  CYS 34  37  37  CYS CYS C . n 
B 2 35  PHE 35  38  38  PHE PHE C . n 
B 2 36  VAL 36  39  39  VAL VAL C . n 
B 2 37  PRO 37  40  40  PRO PRO C . n 
B 2 38  ASP 38  41  41  ASP ASP C . n 
B 2 39  ASP 39  42  42  ASP ASP C . n 
B 2 40  LYS 40  43  43  LYS LYS C . n 
B 2 41  GLU 41  44  44  GLU GLU C . n 
B 2 42  GLU 42  45  45  GLU GLU C . n 
B 2 43  TYR 43  46  46  TYR TYR C . n 
B 2 44  VAL 44  47  47  VAL VAL C . n 
B 2 45  LYS 45  48  48  LYS LYS C . n 
B 2 46  ALA 46  49  49  ALA ALA C . n 
B 2 47  LYS 47  50  50  LYS LYS C . n 
B 2 48  VAL 48  51  ?   ?   ?   C . n 
B 2 49  VAL 49  52  ?   ?   ?   C . n 
B 2 50  SER 50  53  ?   ?   ?   C . n 
B 2 51  ARG 51  54  ?   ?   ?   C . n 
B 2 52  GLU 52  55  ?   ?   ?   C . n 
B 2 53  GLY 53  56  ?   ?   ?   C . n 
B 2 54  GLY 54  57  ?   ?   ?   C . n 
B 2 55  LYS 55  58  ?   ?   ?   C . n 
B 2 56  VAL 56  59  ?   ?   ?   C . n 
B 2 57  THR 57  60  ?   ?   ?   C . n 
B 2 58  ALA 58  61  61  ALA ALA C . n 
B 2 59  GLU 59  62  62  GLU GLU C . n 
B 2 60  THR 60  63  63  THR THR C . n 
B 2 61  GLU 61  64  64  GLU GLU C . n 
B 2 62  ASN 62  65  65  ASN ASN C . n 
B 2 63  GLY 63  66  66  GLY GLY C . n 
B 2 64  LYS 64  67  67  LYS LYS C . n 
B 2 65  THR 65  68  68  THR THR C . n 
B 2 66  VAL 66  69  69  VAL VAL C . n 
B 2 67  THR 67  70  70  THR THR C . n 
B 2 68  ILE 68  71  71  ILE ILE C . n 
B 2 69  LYS 69  72  72  LYS LYS C . n 
B 2 70  GLU 70  73  73  GLU GLU C . n 
B 2 71  ASP 71  74  74  ASP ASP C . n 
B 2 72  GLN 72  75  75  GLN GLN C . n 
B 2 73  VAL 73  76  76  VAL VAL C . n 
B 2 74  MET 74  77  77  MET MET C . n 
B 2 75  GLN 75  78  78  GLN GLN C . n 
B 2 76  GLN 76  79  79  GLN GLN C . n 
B 2 77  ASN 77  80  80  ASN ASN C . n 
B 2 78  PRO 78  81  81  PRO PRO C . n 
B 2 79  PRO 79  82  82  PRO PRO C . n 
B 2 80  LYS 80  83  83  LYS LYS C . n 
B 2 81  PHE 81  84  84  PHE PHE C . n 
B 2 82  ASP 82  85  85  ASP ASP C . n 
B 2 83  LYS 83  86  86  LYS LYS C . n 
B 2 84  ILE 84  87  87  ILE ILE C . n 
B 2 85  GLU 85  88  88  GLU GLU C . n 
B 2 86  ASP 86  89  89  ASP ASP C . n 
B 2 87  MET 87  90  90  MET MET C . n 
B 2 88  ALA 88  91  91  ALA ALA C . n 
B 2 89  MET 89  92  92  MET MET C . n 
B 2 90  LEU 90  93  93  LEU LEU C . n 
B 2 91  THR 91  94  94  THR THR C . n 
B 2 92  PHE 92  95  95  PHE PHE C . n 
B 2 93  LEU 93  96  96  LEU LEU C . n 
B 2 94  HIS 94  97  97  HIS HIS C . n 
B 2 95  GLU 95  98  98  GLU GLU C . n 
B 2 96  PRO 96  99  99  PRO PRO C . n 
B 2 97  ALA 97  100 100 ALA ALA C . n 
B 2 98  VAL 98  101 101 VAL VAL C . n 
B 2 99  LEU 99  102 102 LEU LEU C . n 
B 2 100 TYR 100 103 103 TYR TYR C . n 
B 2 101 ASN 101 104 104 ASN ASN C . n 
B 2 102 LEU 102 105 105 LEU LEU C . n 
B 2 103 LYS 103 106 106 LYS LYS C . n 
B 2 104 GLU 104 107 107 GLU GLU C . n 
B 2 105 ARG 105 108 108 ARG ARG C . n 
B 2 106 TYR 106 109 109 TYR TYR C . n 
B 2 107 ALA 107 110 110 ALA ALA C . n 
B 2 108 ALA 108 111 111 ALA ALA C . n 
B 2 109 TRP 109 112 112 TRP TRP C . n 
B 2 110 MET 110 113 113 MET MET C . n 
B 2 111 ILE 111 114 114 ILE ILE C . n 
B 2 112 TYR 112 115 115 TYR TYR C . n 
B 2 113 THR 113 116 116 THR THR C . n 
B 2 114 TYR 114 117 117 TYR TYR C . n 
B 2 115 SER 115 118 118 SER SER C . n 
B 2 116 GLY 116 119 119 GLY GLY C . n 
B 2 117 LEU 117 120 120 LEU LEU C . n 
B 2 118 PHE 118 121 121 PHE PHE C . n 
B 2 119 CYS 119 122 122 CYS CYS C . n 
B 2 120 VAL 120 123 123 VAL VAL C . n 
B 2 121 THR 121 124 124 THR THR C . n 
B 2 122 VAL 122 125 125 VAL VAL C . n 
B 2 123 ASN 123 126 126 ASN ASN C . n 
B 2 124 PRO 124 127 127 PRO PRO C . n 
B 2 125 TYR 125 128 128 TYR TYR C . n 
B 2 126 LYS 126 129 129 LYS LYS C . n 
B 2 127 TRP 127 130 130 TRP TRP C . n 
B 2 128 LEU 128 131 131 LEU LEU C . n 
B 2 129 PRO 129 132 132 PRO PRO C . n 
B 2 130 VAL 130 133 133 VAL VAL C . n 
B 2 131 TYR 131 134 134 TYR TYR C . n 
B 2 132 ASN 132 135 135 ASN ASN C . n 
B 2 133 ALA 133 136 136 ALA ALA C . n 
B 2 134 GLU 134 137 137 GLU GLU C . n 
B 2 135 VAL 135 138 138 VAL VAL C . n 
B 2 136 VAL 136 139 139 VAL VAL C . n 
B 2 137 ALA 137 140 140 ALA ALA C . n 
B 2 138 ALA 138 141 141 ALA ALA C . n 
B 2 139 TYR 139 142 142 TYR TYR C . n 
B 2 140 ARG 140 143 143 ARG ARG C . n 
B 2 141 GLY 141 144 144 GLY GLY C . n 
B 2 142 LYS 142 145 145 LYS LYS C . n 
B 2 143 LYS 143 146 146 LYS LYS C . n 
B 2 144 ARG 144 147 147 ARG ARG C . n 
B 2 145 SER 145 148 148 SER SER C . n 
B 2 146 GLU 146 149 149 GLU GLU C . n 
B 2 147 ALA 147 150 150 ALA ALA C . n 
B 2 148 PRO 148 151 151 PRO PRO C . n 
B 2 149 PRO 149 152 152 PRO PRO C . n 
B 2 150 HIS 150 153 153 HIS HIS C . n 
B 2 151 ILE 151 154 154 ILE ILE C . n 
B 2 152 PHE 152 155 155 PHE PHE C . n 
B 2 153 SER 153 156 156 SER SER C . n 
B 2 154 ILE 154 157 157 ILE ILE C . n 
B 2 155 SER 155 158 158 SER SER C . n 
B 2 156 ASP 156 159 159 ASP ASP C . n 
B 2 157 ASN 157 160 160 ASN ASN C . n 
B 2 158 ALA 158 161 161 ALA ALA C . n 
B 2 159 TYR 159 162 162 TYR TYR C . n 
B 2 160 GLN 160 163 163 GLN GLN C . n 
B 2 161 TYR 161 164 164 TYR TYR C . n 
B 2 162 MET 162 165 165 MET MET C . n 
B 2 163 LEU 163 166 166 LEU LEU C . n 
B 2 164 THR 164 167 167 THR THR C . n 
B 2 165 ASP 165 168 168 ASP ASP C . n 
B 2 166 ARG 166 169 169 ARG ARG C . n 
B 2 167 GLU 167 170 170 GLU GLU C . n 
B 2 168 ASN 168 171 171 ASN ASN C . n 
B 2 169 GLN 169 172 172 GLN GLN C . n 
B 2 170 SER 170 173 173 SER SER C . n 
B 2 171 ILE 171 174 174 ILE ILE C . n 
B 2 172 LEU 172 175 175 LEU LEU C . n 
B 2 173 ILE 173 176 176 ILE ILE C . n 
B 2 174 THR 174 177 177 THR THR C . n 
B 2 175 GLY 175 178 178 GLY GLY C . n 
B 2 176 GLU 176 179 179 GLU GLU C . n 
B 2 177 SER 177 180 180 SER SER C . n 
B 2 178 GLY 178 181 181 GLY GLY C . n 
B 2 179 ALA 179 182 182 ALA ALA C . n 
B 2 180 GLY 180 183 183 GLY GLY C . n 
B 2 181 LYS 181 184 184 LYS LYS C . n 
B 2 182 THR 182 185 185 THR THR C . n 
B 2 183 VAL 183 186 186 VAL VAL C . n 
B 2 184 ASN 184 187 187 ASN ASN C . n 
B 2 185 THR 185 188 188 THR THR C . n 
B 2 186 LYS 186 189 189 LYS LYS C . n 
B 2 187 ARG 187 190 190 ARG ARG C . n 
B 2 188 VAL 188 191 191 VAL VAL C . n 
B 2 189 ILE 189 192 192 ILE ILE C . n 
B 2 190 GLN 190 193 193 GLN GLN C . n 
B 2 191 TYR 191 194 194 TYR TYR C . n 
B 2 192 PHE 192 195 195 PHE PHE C . n 
B 2 193 ALA 193 196 196 ALA ALA C . n 
B 2 194 SER 194 197 197 SER SER C . n 
B 2 195 ILE 195 198 198 ILE ILE C . n 
B 2 196 ALA 196 199 199 ALA ALA C . n 
B 2 197 ALA 197 200 200 ALA ALA C . n 
B 2 198 ILE 198 201 ?   ?   ?   C . n 
B 2 199 GLY 199 202 ?   ?   ?   C . n 
B 2 200 ASP 200 203 ?   ?   ?   C . n 
B 2 201 ARG 201 204 ?   ?   ?   C . n 
B 2 202 SER 202 205 ?   ?   ?   C . n 
B 2 203 LYS 203 206 ?   ?   ?   C . n 
B 2 204 LYS 204 207 ?   ?   ?   C . n 
B 2 205 GLU 205 208 ?   ?   ?   C . n 
B 2 206 ASN 206 209 ?   ?   ?   C . n 
B 2 207 PRO 207 210 ?   ?   ?   C . n 
B 2 208 ASN 208 211 ?   ?   ?   C . n 
B 2 209 ALA 209 212 ?   ?   ?   C . n 
B 2 210 ASN 210 213 ?   ?   ?   C . n 
B 2 211 LYS 211 214 ?   ?   ?   C . n 
B 2 212 GLY 212 215 215 GLY GLY C . n 
B 2 213 THR 213 216 216 THR THR C . n 
B 2 214 LEU 214 217 217 LEU LEU C . n 
B 2 215 GLU 215 218 218 GLU GLU C . n 
B 2 216 ASP 216 219 219 ASP ASP C . n 
B 2 217 GLN 217 220 220 GLN GLN C . n 
B 2 218 ILE 218 221 221 ILE ILE C . n 
B 2 219 ILE 219 222 222 ILE ILE C . n 
B 2 220 GLN 220 223 223 GLN GLN C . n 
B 2 221 ALA 221 224 224 ALA ALA C . n 
B 2 222 ASN 222 225 225 ASN ASN C . n 
B 2 223 PRO 223 226 226 PRO PRO C . n 
B 2 224 ALA 224 227 227 ALA ALA C . n 
B 2 225 LEU 225 228 228 LEU LEU C . n 
B 2 226 GLU 226 229 229 GLU GLU C . n 
B 2 227 ALA 227 230 230 ALA ALA C . n 
B 2 228 PHE 228 231 231 PHE PHE C . n 
B 2 229 GLY 229 232 232 GLY GLY C . n 
B 2 230 ASN 230 233 233 ASN ASN C . n 
B 2 231 ALA 231 234 234 ALA ALA C . n 
B 2 232 LYS 232 235 235 LYS LYS C . n 
B 2 233 THR 233 236 236 THR THR C . n 
B 2 234 VAL 234 237 237 VAL VAL C . n 
B 2 235 ARG 235 238 238 ARG ARG C . n 
B 2 236 ASN 236 239 239 ASN ASN C . n 
B 2 237 ASP 237 240 240 ASP ASP C . n 
B 2 238 ASN 238 241 241 ASN ASN C . n 
B 2 239 SER 239 242 242 SER SER C . n 
B 2 240 SER 240 243 243 SER SER C . n 
B 2 241 ARG 241 244 244 ARG ARG C . n 
B 2 242 PHE 242 245 245 PHE PHE C . n 
B 2 243 GLY 243 246 246 GLY GLY C . n 
B 2 244 LYS 244 247 247 LYS LYS C . n 
B 2 245 PHE 245 248 248 PHE PHE C . n 
B 2 246 ILE 246 249 249 ILE ILE C . n 
B 2 247 ARG 247 250 250 ARG ARG C . n 
B 2 248 ILE 248 251 251 ILE ILE C . n 
B 2 249 HIS 249 252 252 HIS HIS C . n 
B 2 250 PHE 250 253 253 PHE PHE C . n 
B 2 251 GLY 251 254 254 GLY GLY C . n 
B 2 252 ALA 252 255 255 ALA ALA C . n 
B 2 253 THR 253 256 256 THR THR C . n 
B 2 254 GLY 254 257 257 GLY GLY C . n 
B 2 255 LYS 255 258 258 LYS LYS C . n 
B 2 256 LEU 256 259 259 LEU LEU C . n 
B 2 257 ALA 257 260 260 ALA ALA C . n 
B 2 258 SER 258 261 261 SER SER C . n 
B 2 259 ALA 259 262 262 ALA ALA C . n 
B 2 260 ASP 260 263 263 ASP ASP C . n 
B 2 261 ILE 261 264 264 ILE ILE C . n 
B 2 262 GLU 262 265 265 GLU GLU C . n 
B 2 263 THR 263 266 266 THR THR C . n 
B 2 264 TYR 264 267 267 TYR TYR C . n 
B 2 265 LEU 265 268 268 LEU LEU C . n 
B 2 266 LEU 266 269 269 LEU LEU C . n 
B 2 267 GLU 267 270 270 GLU GLU C . n 
B 2 268 LYS 268 271 271 LYS LYS C . n 
B 2 269 SER 269 272 272 SER SER C . n 
B 2 270 ARG 270 273 273 ARG ARG C . n 
B 2 271 VAL 271 274 274 VAL VAL C . n 
B 2 272 ILE 272 275 275 ILE ILE C . n 
B 2 273 PHE 273 276 276 PHE PHE C . n 
B 2 274 GLN 274 277 277 GLN GLN C . n 
B 2 275 LEU 275 278 278 LEU LEU C . n 
B 2 276 LYS 276 279 279 LYS LYS C . n 
B 2 277 ALA 277 280 280 ALA ALA C . n 
B 2 278 GLU 278 281 281 GLU GLU C . n 
B 2 279 ARG 279 282 282 ARG ARG C . n 
B 2 280 ASN 280 283 283 ASN ASN C . n 
B 2 281 TYR 281 284 284 TYR TYR C . n 
B 2 282 HIS 282 285 285 HIS HIS C . n 
B 2 283 ILE 283 286 286 ILE ILE C . n 
B 2 284 PHE 284 287 287 PHE PHE C . n 
B 2 285 TYR 285 288 288 TYR TYR C . n 
B 2 286 GLN 286 289 289 GLN GLN C . n 
B 2 287 ILE 287 290 290 ILE ILE C . n 
B 2 288 LEU 288 291 291 LEU LEU C . n 
B 2 289 SER 289 292 292 SER SER C . n 
B 2 290 ASN 290 293 293 ASN ASN C . n 
B 2 291 LYS 291 294 294 LYS LYS C . n 
B 2 292 LYS 292 295 295 LYS LYS C . n 
B 2 293 PRO 293 296 296 PRO PRO C . n 
B 2 294 GLU 294 297 297 GLU GLU C . n 
B 2 295 LEU 295 298 298 LEU LEU C . n 
B 2 296 LEU 296 299 299 LEU LEU C . n 
B 2 297 ASP 297 300 300 ASP ASP C . n 
B 2 298 MET 298 301 301 MET MET C . n 
B 2 299 LEU 299 302 302 LEU LEU C . n 
B 2 300 LEU 300 303 303 LEU LEU C . n 
B 2 301 VAL 301 304 304 VAL VAL C . n 
B 2 302 THR 302 305 305 THR THR C . n 
B 2 303 ASN 303 306 306 ASN ASN C . n 
B 2 304 ASN 304 307 307 ASN ASN C . n 
B 2 305 PRO 305 308 308 PRO PRO C . n 
B 2 306 TYR 306 309 309 TYR TYR C . n 
B 2 307 ASP 307 310 310 ASP ASP C . n 
B 2 308 TYR 308 311 311 TYR TYR C . n 
B 2 309 ALA 309 312 312 ALA ALA C . n 
B 2 310 PHE 310 313 313 PHE PHE C . n 
B 2 311 VAL 311 314 314 VAL VAL C . n 
B 2 312 SER 312 315 315 SER SER C . n 
B 2 313 GLN 313 316 316 GLN GLN C . n 
B 2 314 GLY 314 317 317 GLY GLY C . n 
B 2 315 GLU 315 318 318 GLU GLU C . n 
B 2 316 VAL 316 319 319 VAL VAL C . n 
B 2 317 SER 317 320 320 SER SER C . n 
B 2 318 VAL 318 321 321 VAL VAL C . n 
B 2 319 ALA 319 322 322 ALA ALA C . n 
B 2 320 SER 320 323 323 SER SER C . n 
B 2 321 ILE 321 324 324 ILE ILE C . n 
B 2 322 ASP 322 325 325 ASP ASP C . n 
B 2 323 ASP 323 326 326 ASP ASP C . n 
B 2 324 SER 324 327 327 SER SER C . n 
B 2 325 GLU 325 328 328 GLU GLU C . n 
B 2 326 GLU 326 329 329 GLU GLU C . n 
B 2 327 LEU 327 330 330 LEU LEU C . n 
B 2 328 LEU 328 331 331 LEU LEU C . n 
B 2 329 ALA 329 332 332 ALA ALA C . n 
B 2 330 THR 330 333 333 THR THR C . n 
B 2 331 ASP 331 334 334 ASP ASP C . n 
B 2 332 SER 332 335 335 SER SER C . n 
B 2 333 ALA 333 336 336 ALA ALA C . n 
B 2 334 PHE 334 337 337 PHE PHE C . n 
B 2 335 ASP 335 338 338 ASP ASP C . n 
B 2 336 VAL 336 339 339 VAL VAL C . n 
B 2 337 LEU 337 340 340 LEU LEU C . n 
B 2 338 SER 338 341 341 SER SER C . n 
B 2 339 PHE 339 342 342 PHE PHE C . n 
B 2 340 THR 340 343 343 THR THR C . n 
B 2 341 ALA 341 344 344 ALA ALA C . n 
B 2 342 GLU 342 345 345 GLU GLU C . n 
B 2 343 GLU 343 346 346 GLU GLU C . n 
B 2 344 LYS 344 347 347 LYS LYS C . n 
B 2 345 ALA 345 348 348 ALA ALA C . n 
B 2 346 GLY 346 349 349 GLY GLY C . n 
B 2 347 VAL 347 350 350 VAL VAL C . n 
B 2 348 TYR 348 351 351 TYR TYR C . n 
B 2 349 LYS 349 352 352 LYS LYS C . n 
B 2 350 LEU 350 353 353 LEU LEU C . n 
B 2 351 THR 351 354 354 THR THR C . n 
B 2 352 GLY 352 355 355 GLY GLY C . n 
B 2 353 ALA 353 356 356 ALA ALA C . n 
B 2 354 ILE 354 357 357 ILE ILE C . n 
B 2 355 MET 355 358 358 MET MET C . n 
B 2 356 HIS 356 359 359 HIS HIS C . n 
B 2 357 TYR 357 360 360 TYR TYR C . n 
B 2 358 GLY 358 361 361 GLY GLY C . n 
B 2 359 ASN 359 362 362 ASN ASN C . n 
B 2 360 MET 360 363 363 MET MET C . n 
B 2 361 LYS 361 364 364 LYS LYS C . n 
B 2 362 PHE 362 365 365 PHE PHE C . n 
B 2 363 LYS 363 366 366 LYS LYS C . n 
B 2 364 GLN 364 367 367 GLN GLN C . n 
B 2 365 LYS 365 368 368 LYS LYS C . n 
B 2 366 GLN 366 369 369 GLN GLN C . n 
B 2 367 ARG 367 370 370 ARG ARG C . n 
B 2 368 GLU 368 371 371 GLU GLU C . n 
B 2 369 GLU 369 372 372 GLU GLU C . n 
B 2 370 GLN 370 373 373 GLN GLN C . n 
B 2 371 ALA 371 374 374 ALA ALA C . n 
B 2 372 GLU 372 375 375 GLU GLU C . n 
B 2 373 PRO 373 376 376 PRO PRO C . n 
B 2 374 ASP 374 377 377 ASP ASP C . n 
B 2 375 GLY 375 378 378 GLY GLY C . n 
B 2 376 THR 376 379 379 THR THR C . n 
B 2 377 GLU 377 380 380 GLU GLU C . n 
B 2 378 ASP 378 381 381 ASP ASP C . n 
B 2 379 ALA 379 382 382 ALA ALA C . n 
B 2 380 ASP 380 383 383 ASP ASP C . n 
B 2 381 LYS 381 384 384 LYS LYS C . n 
B 2 382 SER 382 385 385 SER SER C . n 
B 2 383 ALA 383 386 386 ALA ALA C . n 
B 2 384 TYR 384 387 387 TYR TYR C . n 
B 2 385 LEU 385 388 388 LEU LEU C . n 
B 2 386 MET 386 389 389 MET MET C . n 
B 2 387 GLY 387 390 390 GLY GLY C . n 
B 2 388 LEU 388 391 391 LEU LEU C . n 
B 2 389 ASN 389 392 392 ASN ASN C . n 
B 2 390 SER 390 393 393 SER SER C . n 
B 2 391 ALA 391 394 394 ALA ALA C . n 
B 2 392 ASP 392 395 395 ASP ASP C . n 
B 2 393 LEU 393 396 396 LEU LEU C . n 
B 2 394 LEU 394 397 397 LEU LEU C . n 
B 2 395 LYS 395 398 398 LYS LYS C . n 
B 2 396 GLY 396 399 399 GLY GLY C . n 
B 2 397 LEU 397 400 400 LEU LEU C . n 
B 2 398 CYS 398 401 401 CYS CYS C . n 
B 2 399 HIS 399 402 402 HIS HIS C . n 
B 2 400 PRO 400 403 403 PRO PRO C . n 
B 2 401 GLN 401 404 404 GLN GLN C . n 
B 2 402 VAL 402 405 405 VAL VAL C . n 
B 2 403 LYS 403 406 406 LYS LYS C . n 
B 2 404 VAL 404 407 407 VAL VAL C . n 
B 2 405 GLY 405 408 408 GLY GLY C . n 
B 2 406 ASN 406 409 409 ASN ASN C . n 
B 2 407 GLU 407 410 410 GLU GLU C . n 
B 2 408 TYR 408 411 411 TYR TYR C . n 
B 2 409 VAL 409 412 412 VAL VAL C . n 
B 2 410 THR 410 413 413 THR THR C . n 
B 2 411 LYS 411 414 414 LYS LYS C . n 
B 2 412 GLY 412 415 415 GLY GLY C . n 
B 2 413 GLN 413 416 416 GLN GLN C . n 
B 2 414 SER 414 417 417 SER SER C . n 
B 2 415 VAL 415 418 418 VAL VAL C . n 
B 2 416 GLN 416 419 419 GLN GLN C . n 
B 2 417 GLN 417 420 420 GLN GLN C . n 
B 2 418 VAL 418 421 421 VAL VAL C . n 
B 2 419 TYR 419 422 422 TYR TYR C . n 
B 2 420 TYR 420 423 423 TYR TYR C . n 
B 2 421 SER 421 424 424 SER SER C . n 
B 2 422 ILE 422 425 425 ILE ILE C . n 
B 2 423 GLY 423 426 426 GLY GLY C . n 
B 2 424 ALA 424 427 427 ALA ALA C . n 
B 2 425 LEU 425 428 428 LEU LEU C . n 
B 2 426 ALA 426 429 429 ALA ALA C . n 
B 2 427 LYS 427 430 430 LYS LYS C . n 
B 2 428 SER 428 431 431 SER SER C . n 
B 2 429 VAL 429 432 432 VAL VAL C . n 
B 2 430 TYR 430 433 433 TYR TYR C . n 
B 2 431 GLU 431 434 434 GLU GLU C . n 
B 2 432 LYS 432 435 435 LYS LYS C . n 
B 2 433 MET 433 436 436 MET MET C . n 
B 2 434 PHE 434 437 437 PHE PHE C . n 
B 2 435 ASN 435 438 438 ASN ASN C . n 
B 2 436 TRP 436 439 439 TRP TRP C . n 
B 2 437 MET 437 440 440 MET MET C . n 
B 2 438 VAL 438 441 441 VAL VAL C . n 
B 2 439 THR 439 442 442 THR THR C . n 
B 2 440 ARG 440 443 443 ARG ARG C . n 
B 2 441 ILE 441 444 444 ILE ILE C . n 
B 2 442 ASN 442 445 445 ASN ASN C . n 
B 2 443 ALA 443 446 446 ALA ALA C . n 
B 2 444 THR 444 447 447 THR THR C . n 
B 2 445 LEU 445 448 448 LEU LEU C . n 
B 2 446 GLU 446 449 449 GLU GLU C . n 
B 2 447 THR 447 450 450 THR THR C . n 
B 2 448 LYS 448 451 451 LYS LYS C . n 
B 2 449 GLN 449 452 452 GLN GLN C . n 
B 2 450 PRO 450 453 453 PRO PRO C . n 
B 2 451 ARG 451 454 454 ARG ARG C . n 
B 2 452 GLN 452 455 455 GLN GLN C . n 
B 2 453 TYR 453 456 456 TYR TYR C . n 
B 2 454 PHE 454 457 457 PHE PHE C . n 
B 2 455 ILE 455 458 458 ILE ILE C . n 
B 2 456 GLY 456 459 459 GLY GLY C . n 
B 2 457 VAL 457 460 460 VAL VAL C . n 
B 2 458 LEU 458 461 461 LEU LEU C . n 
B 2 459 ASP 459 462 462 ASP ASP C . n 
B 2 460 ILE 460 463 463 ILE ILE C . n 
B 2 461 ALA 461 464 464 ALA ALA C . n 
B 2 462 GLY 462 465 465 GLY GLY C . n 
B 2 463 PHE 463 466 466 PHE PHE C . n 
B 2 464 GLU 464 467 467 GLU GLU C . n 
B 2 465 ILE 465 468 468 ILE ILE C . n 
B 2 466 PHE 466 469 469 PHE PHE C . n 
B 2 467 ASP 467 470 470 ASP ASP C . n 
B 2 468 PHE 468 471 471 PHE PHE C . n 
B 2 469 ASN 469 472 472 ASN ASN C . n 
B 2 470 SER 470 473 473 SER SER C . n 
B 2 471 PHE 471 474 474 PHE PHE C . n 
B 2 472 GLU 472 475 475 GLU GLU C . n 
B 2 473 GLN 473 476 476 GLN GLN C . n 
B 2 474 LEU 474 477 477 LEU LEU C . n 
B 2 475 CYS 475 478 478 CYS CYS C . n 
B 2 476 ILE 476 479 479 ILE ILE C . n 
B 2 477 ASN 477 480 480 ASN ASN C . n 
B 2 478 PHE 478 481 481 PHE PHE C . n 
B 2 479 THR 479 482 482 THR THR C . n 
B 2 480 ASN 480 483 483 ASN ASN C . n 
B 2 481 GLU 481 484 484 GLU GLU C . n 
B 2 482 LYS 482 485 485 LYS LYS C . n 
B 2 483 LEU 483 486 486 LEU LEU C . n 
B 2 484 GLN 484 487 487 GLN GLN C . n 
B 2 485 GLN 485 488 488 GLN GLN C . n 
B 2 486 PHE 486 489 489 PHE PHE C . n 
B 2 487 PHE 487 490 490 PHE PHE C . n 
B 2 488 ASN 488 491 491 ASN ASN C . n 
B 2 489 HIS 489 492 492 HIS HIS C . n 
B 2 490 HIS 490 493 493 HIS HIS C . n 
B 2 491 MET 491 494 494 MET MET C . n 
B 2 492 PHE 492 495 495 PHE PHE C . n 
B 2 493 VAL 493 496 496 VAL VAL C . n 
B 2 494 LEU 494 497 497 LEU LEU C . n 
B 2 495 GLU 495 498 498 GLU GLU C . n 
B 2 496 GLN 496 499 499 GLN GLN C . n 
B 2 497 GLU 497 500 500 GLU GLU C . n 
B 2 498 GLU 498 501 501 GLU GLU C . n 
B 2 499 TYR 499 502 502 TYR TYR C . n 
B 2 500 LYS 500 503 503 LYS LYS C . n 
B 2 501 LYS 501 504 504 LYS LYS C . n 
B 2 502 GLU 502 505 505 GLU GLU C . n 
B 2 503 GLY 503 506 506 GLY GLY C . n 
B 2 504 ILE 504 507 507 ILE ILE C . n 
B 2 505 GLU 505 508 508 GLU GLU C . n 
B 2 506 TRP 506 509 509 TRP TRP C . n 
B 2 507 GLU 507 510 510 GLU GLU C . n 
B 2 508 PHE 508 511 511 PHE PHE C . n 
B 2 509 ILE 509 512 512 ILE ILE C . n 
B 2 510 ASP 510 513 513 ASP ASP C . n 
B 2 511 PHE 511 514 514 PHE PHE C . n 
B 2 512 GLY 512 515 515 GLY GLY C . n 
B 2 513 MET 513 516 516 MET MET C . n 
B 2 514 ASP 514 517 517 ASP ASP C . n 
B 2 515 LEU 515 518 518 LEU LEU C . n 
B 2 516 GLN 516 519 519 GLN GLN C . n 
B 2 517 ALA 517 520 520 ALA ALA C . n 
B 2 518 CYS 518 521 521 CYS CYS C . n 
B 2 519 ILE 519 522 522 ILE ILE C . n 
B 2 520 ASP 520 523 523 ASP ASP C . n 
B 2 521 LEU 521 524 524 LEU LEU C . n 
B 2 522 ILE 522 525 525 ILE ILE C . n 
B 2 523 GLU 523 526 526 GLU GLU C . n 
B 2 524 LYS 524 527 527 LYS LYS C . n 
B 2 525 PRO 525 528 528 PRO PRO C . n 
B 2 526 MET 526 529 529 MET MET C . n 
B 2 527 GLY 527 530 530 GLY GLY C . n 
B 2 528 ILE 528 531 531 ILE ILE C . n 
B 2 529 MET 529 532 532 MET MET C . n 
B 2 530 SER 530 533 533 SER SER C . n 
B 2 531 ILE 531 534 534 ILE ILE C . n 
B 2 532 LEU 532 535 535 LEU LEU C . n 
B 2 533 GLU 533 536 536 GLU GLU C . n 
B 2 534 GLU 534 537 537 GLU GLU C . n 
B 2 535 GLU 535 538 538 GLU GLU C . n 
B 2 536 CYS 536 539 539 CYS CYS C . n 
B 2 537 MET 537 540 540 MET MET C . n 
B 2 538 PHE 538 541 541 PHE PHE C . n 
B 2 539 PRO 539 542 542 PRO PRO C . n 
B 2 540 LYS 540 543 543 LYS LYS C . n 
B 2 541 ALA 541 544 544 ALA ALA C . n 
B 2 542 SER 542 545 545 SER SER C . n 
B 2 543 ASP 543 546 546 ASP ASP C . n 
B 2 544 MET 544 547 547 MET MET C . n 
B 2 545 THR 545 548 548 THR THR C . n 
B 2 546 PHE 546 549 549 PHE PHE C . n 
B 2 547 LYS 547 550 550 LYS LYS C . n 
B 2 548 ALA 548 551 551 ALA ALA C . n 
B 2 549 LYS 549 552 552 LYS LYS C . n 
B 2 550 LEU 550 553 553 LEU LEU C . n 
B 2 551 TYR 551 554 554 TYR TYR C . n 
B 2 552 ASP 552 555 555 ASP ASP C . n 
B 2 553 ASN 553 556 556 ASN ASN C . n 
B 2 554 HIS 554 557 557 HIS HIS C . n 
B 2 555 LEU 555 558 558 LEU LEU C . n 
B 2 556 GLY 556 559 559 GLY GLY C . n 
B 2 557 LYS 557 560 560 LYS LYS C . n 
B 2 558 SER 558 561 561 SER SER C . n 
B 2 559 ASN 559 562 562 ASN ASN C . n 
B 2 560 ASN 560 563 563 ASN ASN C . n 
B 2 561 PHE 561 564 564 PHE PHE C . n 
B 2 562 GLN 562 565 565 GLN GLN C . n 
B 2 563 LYS 563 566 566 LYS LYS C . n 
B 2 564 PRO 564 567 567 PRO PRO C . n 
B 2 565 ARG 565 568 568 ARG ARG C . n 
B 2 566 ASN 566 569 569 ASN ASN C . n 
B 2 567 VAL 567 570 570 VAL VAL C . n 
B 2 568 LYS 568 571 571 LYS LYS C . n 
B 2 569 GLY 569 572 572 GLY GLY C . n 
B 2 570 LYS 570 573 573 LYS LYS C . n 
B 2 571 GLN 571 574 574 GLN GLN C . n 
B 2 572 GLU 572 575 575 GLU GLU C . n 
B 2 573 ALA 573 576 576 ALA ALA C . n 
B 2 574 HIS 574 577 577 HIS HIS C . n 
B 2 575 PHE 575 578 578 PHE PHE C . n 
B 2 576 SER 576 579 579 SER SER C . n 
B 2 577 LEU 577 580 580 LEU LEU C . n 
B 2 578 VAL 578 581 581 VAL VAL C . n 
B 2 579 HIS 579 582 582 HIS HIS C . n 
B 2 580 TYR 580 583 583 TYR TYR C . n 
B 2 581 ALA 581 584 584 ALA ALA C . n 
B 2 582 GLY 582 585 585 GLY GLY C . n 
B 2 583 THR 583 586 586 THR THR C . n 
B 2 584 VAL 584 587 587 VAL VAL C . n 
B 2 585 ASP 585 588 588 ASP ASP C . n 
B 2 586 TYR 586 589 589 TYR TYR C . n 
B 2 587 ASN 587 590 590 ASN ASN C . n 
B 2 588 ILE 588 591 591 ILE ILE C . n 
B 2 589 MET 589 592 592 MET MET C . n 
B 2 590 GLY 590 593 593 GLY GLY C . n 
B 2 591 TRP 591 594 594 TRP TRP C . n 
B 2 592 LEU 592 595 595 LEU LEU C . n 
B 2 593 GLU 593 596 596 GLU GLU C . n 
B 2 594 LYS 594 597 597 LYS LYS C . n 
B 2 595 ASN 595 598 598 ASN ASN C . n 
B 2 596 LYS 596 599 599 LYS LYS C . n 
B 2 597 ASP 597 600 600 ASP ASP C . n 
B 2 598 PRO 598 601 601 PRO PRO C . n 
B 2 599 LEU 599 602 602 LEU LEU C . n 
B 2 600 ASN 600 603 603 ASN ASN C . n 
B 2 601 GLU 601 604 604 GLU GLU C . n 
B 2 602 THR 602 605 605 THR THR C . n 
B 2 603 VAL 603 606 606 VAL VAL C . n 
B 2 604 VAL 604 607 607 VAL VAL C . n 
B 2 605 GLY 605 608 608 GLY GLY C . n 
B 2 606 LEU 606 609 609 LEU LEU C . n 
B 2 607 TYR 607 610 610 TYR TYR C . n 
B 2 608 GLN 608 611 611 GLN GLN C . n 
B 2 609 LYS 609 612 612 LYS LYS C . n 
B 2 610 SER 610 613 613 SER SER C . n 
B 2 611 SER 611 614 614 SER SER C . n 
B 2 612 LEU 612 615 615 LEU LEU C . n 
B 2 613 LYS 613 616 616 LYS LYS C . n 
B 2 614 LEU 614 617 617 LEU LEU C . n 
B 2 615 MET 615 618 618 MET MET C . n 
B 2 616 ALA 616 619 619 ALA ALA C . n 
B 2 617 THR 617 620 620 THR THR C . n 
B 2 618 LEU 618 621 621 LEU LEU C . n 
B 2 619 PHE 619 622 622 PHE PHE C . n 
B 2 620 SER 620 623 623 SER SER C . n 
B 2 621 THR 621 624 624 THR THR C . n 
B 2 622 TYR 622 625 ?   ?   ?   C . n 
B 2 623 ALA 623 626 ?   ?   ?   C . n 
B 2 624 SER 624 627 ?   ?   ?   C . n 
B 2 625 ALA 625 628 ?   ?   ?   C . n 
B 2 626 ASP 626 629 ?   ?   ?   C . n 
B 2 627 THR 627 630 ?   ?   ?   C . n 
B 2 628 GLY 628 631 ?   ?   ?   C . n 
B 2 629 ASP 629 632 ?   ?   ?   C . n 
B 2 630 SER 630 633 ?   ?   ?   C . n 
B 2 631 GLY 631 634 ?   ?   ?   C . n 
B 2 632 LYS 632 635 ?   ?   ?   C . n 
B 2 633 GLY 633 636 ?   ?   ?   C . n 
B 2 634 LYS 634 637 637 LYS LYS C . n 
B 2 635 GLY 635 638 ?   ?   ?   C . n 
B 2 636 GLY 636 639 ?   ?   ?   C . n 
B 2 637 LYS 637 640 ?   ?   ?   C . n 
B 2 638 LYS 638 641 ?   ?   ?   C . n 
B 2 639 LYS 639 642 ?   ?   ?   C . n 
B 2 640 GLY 640 643 ?   ?   ?   C . n 
B 2 641 SER 641 644 644 SER SER C . n 
B 2 642 SER 642 645 645 SER SER C . n 
B 2 643 PHE 643 646 646 PHE PHE C . n 
B 2 644 GLN 644 647 647 GLN GLN C . n 
B 2 645 THR 645 648 648 THR THR C . n 
B 2 646 VAL 646 649 649 VAL VAL C . n 
B 2 647 SER 647 650 650 SER SER C . n 
B 2 648 ALA 648 651 651 ALA ALA C . n 
B 2 649 LEU 649 652 652 LEU LEU C . n 
B 2 650 HIS 650 653 653 HIS HIS C . n 
B 2 651 ARG 651 654 654 ARG ARG C . n 
B 2 652 GLU 652 655 655 GLU GLU C . n 
B 2 653 ASN 653 656 656 ASN ASN C . n 
B 2 654 LEU 654 657 657 LEU LEU C . n 
B 2 655 ASN 655 658 658 ASN ASN C . n 
B 2 656 LYS 656 659 659 LYS LYS C . n 
B 2 657 LEU 657 660 660 LEU LEU C . n 
B 2 658 MET 658 661 661 MET MET C . n 
B 2 659 THR 659 662 662 THR THR C . n 
B 2 660 ASN 660 663 663 ASN ASN C . n 
B 2 661 LEU 661 664 664 LEU LEU C . n 
B 2 662 LYS 662 665 665 LYS LYS C . n 
B 2 663 THR 663 666 666 THR THR C . n 
B 2 664 THR 664 667 667 THR THR C . n 
B 2 665 HIS 665 668 668 HIS HIS C . n 
B 2 666 PRO 666 669 669 PRO PRO C . n 
B 2 667 HIS 667 670 670 HIS HIS C . n 
B 2 668 PHE 668 671 671 PHE PHE C . n 
B 2 669 VAL 669 672 672 VAL VAL C . n 
B 2 670 ARG 670 673 673 ARG ARG C . n 
B 2 671 CYS 671 674 674 CYS CYS C . n 
B 2 672 ILE 672 675 675 ILE ILE C . n 
B 2 673 ILE 673 676 676 ILE ILE C . n 
B 2 674 PRO 674 677 677 PRO PRO C . n 
B 2 675 ASN 675 678 678 ASN ASN C . n 
B 2 676 GLU 676 679 679 GLU GLU C . n 
B 2 677 ARG 677 680 680 ARG ARG C . n 
B 2 678 LYS 678 681 681 LYS LYS C . n 
B 2 679 ALA 679 682 682 ALA ALA C . n 
B 2 680 PRO 680 683 683 PRO PRO C . n 
B 2 681 GLY 681 684 684 GLY GLY C . n 
B 2 682 VAL 682 685 685 VAL VAL C . n 
B 2 683 MET 683 686 686 MET MET C . n 
B 2 684 ASP 684 687 687 ASP ASP C . n 
B 2 685 ASN 685 688 688 ASN ASN C . n 
B 2 686 PRO 686 689 689 PRO PRO C . n 
B 2 687 LEU 687 690 690 LEU LEU C . n 
B 2 688 VAL 688 691 691 VAL VAL C . n 
B 2 689 MET 689 692 692 MET MET C . n 
B 2 690 HIS 690 693 693 HIS HIS C . n 
B 2 691 GLN 691 694 694 GLN GLN C . n 
B 2 692 LEU 692 695 695 LEU LEU C . n 
B 2 693 ARG 693 696 696 ARG ARG C . n 
B 2 694 CYS 694 697 697 CYS CYS C . n 
B 2 695 ASN 695 698 698 ASN ASN C . n 
B 2 696 GLY 696 699 699 GLY GLY C . n 
B 2 697 VAL 697 700 700 VAL VAL C . n 
B 2 698 LEU 698 701 701 LEU LEU C . n 
B 2 699 GLU 699 702 702 GLU GLU C . n 
B 2 700 GLY 700 703 703 GLY GLY C . n 
B 2 701 ILE 701 704 704 ILE ILE C . n 
B 2 702 ARG 702 705 705 ARG ARG C . n 
B 2 703 ILE 703 706 706 ILE ILE C . n 
B 2 704 CYS 704 707 707 CYS CYS C . n 
B 2 705 ARG 705 708 708 ARG ARG C . n 
B 2 706 LYS 706 709 709 LYS LYS C . n 
B 2 707 GLY 707 710 710 GLY GLY C . n 
B 2 708 PHE 708 711 711 PHE PHE C . n 
B 2 709 PRO 709 712 712 PRO PRO C . n 
B 2 710 ASN 710 713 713 ASN ASN C . n 
B 2 711 ARG 711 714 714 ARG ARG C . n 
B 2 712 ILE 712 715 715 ILE ILE C . n 
B 2 713 LEU 713 716 716 LEU LEU C . n 
B 2 714 TYR 714 717 717 TYR TYR C . n 
B 2 715 GLY 715 718 718 GLY GLY C . n 
B 2 716 ASP 716 719 719 ASP ASP C . n 
B 2 717 PHE 717 720 720 PHE PHE C . n 
B 2 718 ARG 718 721 721 ARG ARG C . n 
B 2 719 GLN 719 722 722 GLN GLN C . n 
B 2 720 ARG 720 723 723 ARG ARG C . n 
B 2 721 TYR 721 724 724 TYR TYR C . n 
B 2 722 ARG 722 725 725 ARG ARG C . n 
B 2 723 ILE 723 726 726 ILE ILE C . n 
B 2 724 LEU 724 727 727 LEU LEU C . n 
B 2 725 ASN 725 728 ?   ?   ?   C . n 
B 2 726 PRO 726 729 ?   ?   ?   C . n 
B 2 727 ALA 727 730 ?   ?   ?   C . n 
B 2 728 ALA 728 731 ?   ?   ?   C . n 
B 2 729 ILE 729 732 ?   ?   ?   C . n 
B 2 730 PRO 730 733 ?   ?   ?   C . n 
B 2 731 GLU 731 734 ?   ?   ?   C . n 
B 2 732 GLY 732 735 ?   ?   ?   C . n 
B 2 733 GLN 733 736 ?   ?   ?   C . n 
B 2 734 PHE 734 737 ?   ?   ?   C . n 
B 2 735 ILE 735 738 ?   ?   ?   C . n 
B 2 736 ASP 736 739 ?   ?   ?   C . n 
B 2 737 SER 737 740 ?   ?   ?   C . n 
B 2 738 ARG 738 741 ?   ?   ?   C . n 
B 2 739 LYS 739 742 ?   ?   ?   C . n 
B 2 740 GLY 740 743 743 GLY GLY C . n 
B 2 741 ALA 741 744 744 ALA ALA C . n 
B 2 742 GLU 742 745 745 GLU GLU C . n 
B 2 743 LYS 743 746 746 LYS LYS C . n 
B 2 744 LEU 744 747 747 LEU LEU C . n 
B 2 745 LEU 745 748 748 LEU LEU C . n 
B 2 746 GLY 746 749 749 GLY GLY C . n 
B 2 747 SER 747 750 750 SER SER C . n 
B 2 748 LEU 748 751 751 LEU LEU C . n 
B 2 749 ASP 749 752 752 ASP ASP C . n 
B 2 750 ILE 750 753 753 ILE ILE C . n 
B 2 751 ASP 751 754 754 ASP ASP C . n 
B 2 752 HIS 752 755 755 HIS HIS C . n 
B 2 753 ASN 753 756 756 ASN ASN C . n 
B 2 754 GLN 754 757 757 GLN GLN C . n 
B 2 755 TYR 755 758 758 TYR TYR C . n 
B 2 756 LYS 756 759 759 LYS LYS C . n 
B 2 757 PHE 757 760 760 PHE PHE C . n 
B 2 758 GLY 758 761 761 GLY GLY C . n 
B 2 759 HIS 759 762 762 HIS HIS C . n 
B 2 760 THR 760 763 763 THR THR C . n 
B 2 761 LYS 761 764 764 LYS LYS C . n 
B 2 762 VAL 762 765 765 VAL VAL C . n 
B 2 763 PHE 763 766 766 PHE PHE C . n 
B 2 764 PHE 764 767 767 PHE PHE C . n 
B 2 765 LYS 765 768 768 LYS LYS C . n 
B 2 766 ALA 766 769 769 ALA ALA C . n 
B 2 767 GLY 767 770 770 GLY GLY C . n 
B 2 768 LEU 768 771 771 LEU LEU C . n 
B 2 769 LEU 769 772 772 LEU LEU C . n 
B 2 770 GLY 770 773 773 GLY GLY C . n 
B 2 771 LEU 771 774 774 LEU LEU C . n 
B 2 772 LEU 772 775 775 LEU LEU C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ADP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ADP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         C 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          ADP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    1 
_pdbx_nonpoly_scheme.pdb_mon_id      ADP 
_pdbx_nonpoly_scheme.auth_mon_id     ADP 
_pdbx_nonpoly_scheme.pdb_strand_id   J 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZIU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZIU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZIU 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ZIU 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 8852  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.581 ? 11955 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.462 ? 5336  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.044 ? 1303  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 1540  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZIU 
_struct.title                        'Mouse MYH6 R404Q left ventricle actin and myosin complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZIU 
_struct_keywords.text            'protein binding, actin, myosin' 
_struct_keywords.pdbx_keywords   'PROTEIN BINDING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP ACTC_MOUSE P68033 ? 1 
;TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEK
IWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVP
IYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPD
GQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPST
MKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKC
;
7 
2 UNP MYH6_MOUSE Q02566 ? 2 
;AQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKVVSREGGKVTAETENGKTVTIKEDQVMQQNPPK
FDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQ
YMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENPNANKGTLEDQIIQANPALEAFGNAKTVRNDNSS
RFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVAS
IDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHP
RVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTN
EKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLYDNHLGKSNN
FQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGKGGKKKG
SSFQTVSALHRENLNKLMTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQR
YRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLL
;
4 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZIU J 1 ? 370 ? P68033 7 ? 376 ? 7 376 
2 2 8ZIU C 1 ? 772 ? Q02566 4 ? 775 ? 4 775 
# 
_struct_ref_seq_dif.align_id                     2 
_struct_ref_seq_dif.pdbx_pdb_id_code             8ZIU 
_struct_ref_seq_dif.mon_id                       GLN 
_struct_ref_seq_dif.pdbx_pdb_strand_id           C 
_struct_ref_seq_dif.seq_num                      401 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   Q02566 
_struct_ref_seq_dif.db_mon_id                    ARG 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          404 
_struct_ref_seq_dif.details                      variant 
_struct_ref_seq_dif.pdbx_auth_seq_num            404 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 52  ? LYS A 57  ? ASP J 58  LYS J 63  1 ? 6  
HELX_P HELX_P2  AA2 ASN A 74  ? ASN A 88  ? ASN J 80  ASN J 94  1 ? 15 
HELX_P HELX_P3  AA3 ALA A 93  ? HIS A 97  ? ALA J 99  HIS J 103 5 ? 5  
HELX_P HELX_P4  AA4 PRO A 108 ? PHE A 123 ? PRO J 114 PHE J 129 1 ? 16 
HELX_P HELX_P5  AA5 GLN A 133 ? GLY A 142 ? GLN J 139 GLY J 148 1 ? 10 
HELX_P HELX_P6  AA6 PRO A 168 ? ILE A 171 ? PRO J 174 ILE J 177 5 ? 4  
HELX_P HELX_P7  AA7 ALA A 177 ? THR A 190 ? ALA J 183 THR J 196 1 ? 14 
HELX_P HELX_P8  AA8 GLU A 191 ? GLY A 193 ? GLU J 197 GLY J 199 5 ? 3  
HELX_P HELX_P9  AA9 THR A 198 ? CYS A 213 ? THR J 204 CYS J 219 1 ? 16 
HELX_P HELX_P10 AB1 ASP A 218 ? SER A 229 ? ASP J 224 SER J 235 1 ? 12 
HELX_P HELX_P11 AB2 ASN A 248 ? CYS A 253 ? ASN J 254 CYS J 259 1 ? 6  
HELX_P HELX_P12 AB3 PRO A 254 ? PHE A 258 ? PRO J 260 PHE J 264 5 ? 5  
HELX_P HELX_P13 AB4 GLN A 259 ? GLY A 264 ? GLN J 265 GLY J 270 5 ? 6  
HELX_P HELX_P14 AB5 GLY A 269 ? LYS A 280 ? GLY J 275 LYS J 286 1 ? 12 
HELX_P HELX_P15 AB6 ILE A 285 ? ALA A 291 ? ILE J 291 ALA J 297 1 ? 7  
HELX_P HELX_P16 AB7 GLY A 298 ? TYR A 302 ? GLY J 304 TYR J 308 5 ? 5  
HELX_P HELX_P17 AB8 GLY A 304 ? ALA A 317 ? GLY J 310 ALA J 323 1 ? 14 
HELX_P HELX_P18 AB9 GLU A 330 ? LYS A 332 ? GLU J 336 LYS J 338 5 ? 3  
HELX_P HELX_P19 AC1 TYR A 333 ? LEU A 345 ? TYR J 339 LEU J 351 1 ? 13 
HELX_P HELX_P20 AC2 SER A 346 ? GLN A 349 ? SER J 352 GLN J 355 5 ? 4  
HELX_P HELX_P21 AC3 LYS A 355 ? GLY A 362 ? LYS J 361 GLY J 368 1 ? 8  
HELX_P HELX_P22 AC4 SER A 364 ? LYS A 369 ? SER J 370 LYS J 375 1 ? 6  
HELX_P HELX_P23 AC5 MET B 3   ? ALA B 8   ? MET C 6   ALA C 11  5 ? 6  
HELX_P HELX_P24 AC6 ALA B 9   ? ARG B 14  ? ALA C 12  ARG C 17  1 ? 6  
HELX_P HELX_P25 AC7 SER B 16  ? GLN B 24  ? SER C 19  GLN C 27  1 ? 9  
HELX_P HELX_P26 AC8 PRO B 78  ? ASP B 82  ? PRO C 81  ASP C 85  5 ? 5  
HELX_P HELX_P27 AC9 ASP B 86  ? LEU B 90  ? ASP C 89  LEU C 93  5 ? 5  
HELX_P HELX_P28 AD1 HIS B 94  ? ALA B 108 ? HIS C 97  ALA C 111 1 ? 15 
HELX_P HELX_P29 AD2 HIS B 150 ? ARG B 166 ? HIS C 153 ARG C 169 1 ? 17 
HELX_P HELX_P30 AD3 GLY B 180 ? ALA B 196 ? GLY C 183 ALA C 199 1 ? 17 
HELX_P HELX_P31 AD4 THR B 213 ? ALA B 221 ? THR C 216 ALA C 224 1 ? 9  
HELX_P HELX_P32 AD5 ALA B 221 ? GLY B 229 ? ALA C 224 GLY C 232 1 ? 9  
HELX_P HELX_P33 AD6 GLU B 267 ? VAL B 271 ? GLU C 270 VAL C 274 5 ? 5  
HELX_P HELX_P34 AD7 HIS B 282 ? SER B 289 ? HIS C 285 SER C 292 1 ? 8  
HELX_P HELX_P35 AD8 LYS B 292 ? LEU B 299 ? LYS C 295 LEU C 302 1 ? 8  
HELX_P HELX_P36 AD9 ASN B 304 ? TYR B 308 ? ASN C 307 TYR C 311 5 ? 5  
HELX_P HELX_P37 AE1 ASP B 322 ? LEU B 337 ? ASP C 325 LEU C 340 1 ? 16 
HELX_P HELX_P38 AE2 ALA B 341 ? GLY B 358 ? ALA C 344 GLY C 361 1 ? 18 
HELX_P HELX_P39 AE3 THR B 376 ? MET B 386 ? THR C 379 MET C 389 1 ? 11 
HELX_P HELX_P40 AE4 ASN B 389 ? HIS B 399 ? ASN C 392 HIS C 402 1 ? 11 
HELX_P HELX_P41 AE5 SER B 414 ? LEU B 445 ? SER C 417 LEU C 448 1 ? 32 
HELX_P HELX_P42 AE6 SER B 470 ? GLU B 502 ? SER C 473 GLU C 505 1 ? 33 
HELX_P HELX_P43 AE7 GLY B 512 ? ALA B 517 ? GLY C 515 ALA C 520 1 ? 6  
HELX_P HELX_P44 AE8 CYS B 518 ? GLU B 523 ? CYS C 521 GLU C 526 5 ? 6  
HELX_P HELX_P45 AE9 GLY B 527 ? PHE B 538 ? GLY C 530 PHE C 541 1 ? 12 
HELX_P HELX_P46 AF1 SER B 542 ? LEU B 555 ? SER C 545 LEU C 558 1 ? 14 
HELX_P HELX_P47 AF2 GLY B 590 ? LYS B 596 ? GLY C 593 LYS C 599 1 ? 7  
HELX_P HELX_P48 AF3 ASN B 600 ? GLN B 608 ? ASN C 603 GLN C 611 1 ? 9  
HELX_P HELX_P49 AF4 LEU B 612 ? PHE B 619 ? LEU C 615 PHE C 622 1 ? 8  
HELX_P HELX_P50 AF5 THR B 645 ? THR B 663 ? THR C 648 THR C 666 1 ? 19 
HELX_P HELX_P51 AF6 ASP B 684 ? ASN B 695 ? ASP C 687 ASN C 698 1 ? 12 
HELX_P HELX_P52 AF7 GLY B 696 ? ARG B 705 ? GLY C 699 ARG C 708 1 ? 10 
HELX_P HELX_P53 AF8 LEU B 713 ? TYR B 721 ? LEU C 716 TYR C 724 1 ? 9  
HELX_P HELX_P54 AF9 ALA B 741 ? GLY B 746 ? ALA C 744 GLY C 749 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 3 ? 
AA3 ? 3 ? 
AA4 ? 5 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
AA7 ? 2 ? 
AA8 ? 7 ? 
AA9 ? 2 ? 
AB1 ? 2 ? 
AB2 ? 2 ? 
AB3 ? 3 ? 
AB4 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 25  ? PHE A 27  ? ALA J 31  PHE J 33  
AA1 2 VAL A 13  ? PHE A 17  ? VAL J 19  PHE J 23  
AA1 3 LEU A 4   ? ASP A 7   ? LEU J 10  ASP J 13  
AA1 4 THR A 99  ? GLU A 103 ? THR J 105 GLU J 109 
AA1 5 ALA A 127 ? ILE A 132 ? ALA J 133 ILE J 138 
AA1 6 ILE A 353 ? SER A 354 ? ILE J 359 SER J 360 
AA2 1 TYR A 49  ? VAL A 50  ? TYR J 55  VAL J 56  
AA2 2 VAL A 31  ? PRO A 34  ? VAL J 37  PRO J 40  
AA2 3 LEU A 61  ? LYS A 64  ? LEU J 67  LYS J 70  
AA3 1 TYR A 165 ? ALA A 166 ? TYR J 171 ALA J 172 
AA3 2 THR A 156 ? TYR A 162 ? THR J 162 TYR J 168 
AA3 3 MET A 172 ? LEU A 174 ? MET J 178 LEU J 180 
AA4 1 TYR A 165 ? ALA A 166 ? TYR J 171 ALA J 172 
AA4 2 THR A 156 ? TYR A 162 ? THR J 162 TYR J 168 
AA4 3 GLY A 146 ? SER A 151 ? GLY J 152 SER J 157 
AA4 4 ASN A 293 ? SER A 296 ? ASN J 299 SER J 302 
AA4 5 ILE A 325 ? ILE A 326 ? ILE J 331 ILE J 332 
AA5 1 LYS A 234 ? GLU A 237 ? LYS J 240 GLU J 243 
AA5 2 VAL A 243 ? ILE A 246 ? VAL J 249 ILE J 252 
AA6 1 TYR B 43  ? ALA B 46  ? TYR C 46  ALA C 49  
AA6 2 CYS B 34  ? PRO B 37  ? CYS C 37  PRO C 40  
AA6 3 MET B 74  ? GLN B 75  ? MET C 77  GLN C 78  
AA7 1 THR B 60  ? GLU B 61  ? THR C 63  GLU C 64  
AA7 2 THR B 65  ? VAL B 66  ? THR C 68  VAL C 69  
AA8 1 TYR B 112 ? SER B 115 ? TYR C 115 SER C 118 
AA8 2 PHE B 118 ? VAL B 122 ? PHE C 121 VAL C 125 
AA8 3 HIS B 665 ? ILE B 672 ? HIS C 668 ILE C 675 
AA8 4 GLN B 169 ? THR B 174 ? GLN C 172 THR C 177 
AA8 5 TYR B 453 ? ILE B 460 ? TYR C 456 ILE C 463 
AA8 6 GLY B 243 ? PHE B 250 ? GLY C 246 PHE C 253 
AA8 7 LEU B 256 ? TYR B 264 ? LEU C 259 TYR C 267 
AA9 1 ASN B 230 ? ALA B 231 ? ASN C 233 ALA C 234 
AA9 2 SER B 239 ? SER B 240 ? SER C 242 SER C 243 
AB1 1 PHE B 362 ? GLN B 364 ? PHE C 365 GLN C 367 
AB1 2 ALA B 371 ? PRO B 373 ? ALA C 374 PRO C 376 
AB2 1 GLN B 401 ? VAL B 404 ? GLN C 404 VAL C 407 
AB2 2 GLU B 407 ? THR B 410 ? GLU C 410 THR C 413 
AB3 1 PHE B 561 ? GLN B 562 ? PHE C 564 GLN C 565 
AB3 2 PHE B 575 ? HIS B 579 ? PHE C 578 HIS C 582 
AB3 3 GLY B 582 ? TYR B 586 ? GLY C 585 TYR C 589 
AB4 1 ASN B 710 ? ILE B 712 ? ASN C 713 ILE C 715 
AB4 2 VAL B 762 ? PHE B 764 ? VAL C 765 PHE C 767 
AB4 3 TYR B 755 ? PHE B 757 ? TYR C 758 PHE C 760 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 25  ? O ALA J 31  N ALA A 15  ? N ALA J 21  
AA1 2 3 O LYS A 14  ? O LYS J 20  N ASP A 7   ? N ASP J 13  
AA1 3 4 N LEU A 4   ? N LEU J 10  O LEU A 100 ? O LEU J 106 
AA1 4 5 N LEU A 101 ? N LEU J 107 O TYR A 129 ? O TYR J 135 
AA1 5 6 N MET A 128 ? N MET J 134 O ILE A 353 ? O ILE J 359 
AA2 1 2 O TYR A 49  ? O TYR J 55  N GLY A 32  ? N GLY J 38  
AA2 2 3 N VAL A 31  ? N VAL J 37  O LYS A 64  ? O LYS J 70  
AA3 1 2 O TYR A 165 ? O TYR J 171 N TYR A 162 ? N TYR J 168 
AA3 2 3 N THR A 156 ? N THR J 162 O LEU A 174 ? O LEU J 180 
AA4 1 2 O TYR A 165 ? O TYR J 171 N TYR A 162 ? N TYR J 168 
AA4 2 3 O ILE A 161 ? O ILE J 167 N GLY A 146 ? N GLY J 152 
AA4 3 4 N LEU A 149 ? N LEU J 155 O VAL A 294 ? O VAL J 300 
AA4 4 5 N ASN A 293 ? N ASN J 299 O ILE A 326 ? O ILE J 332 
AA5 1 2 N TYR A 236 ? N TYR J 242 O ILE A 244 ? O ILE J 250 
AA6 1 2 O VAL B 44  ? O VAL C 47  N VAL B 36  ? N VAL C 39  
AA6 2 3 N PHE B 35  ? N PHE C 38  O MET B 74  ? O MET C 77  
AA7 1 2 N THR B 60  ? N THR C 63  O VAL B 66  ? O VAL C 69  
AA8 1 2 N THR B 113 ? N THR C 116 O VAL B 120 ? O VAL C 123 
AA8 2 3 N THR B 121 ? N THR C 124 O ARG B 670 ? O ARG C 673 
AA8 3 4 O VAL B 669 ? O VAL C 672 N LEU B 172 ? N LEU C 175 
AA8 4 5 N GLN B 169 ? N GLN C 172 O GLY B 456 ? O GLY C 459 
AA8 5 6 O TYR B 453 ? O TYR C 456 N PHE B 250 ? N PHE C 253 
AA8 6 7 N HIS B 249 ? N HIS C 252 O ALA B 257 ? O ALA C 260 
AA9 1 2 N ALA B 231 ? N ALA C 234 O SER B 239 ? O SER C 242 
AB1 1 2 N LYS B 363 ? N LYS C 366 O GLU B 372 ? O GLU C 375 
AB2 1 2 N VAL B 402 ? N VAL C 405 O VAL B 409 ? O VAL C 412 
AB3 1 2 N GLN B 562 ? N GLN C 565 O SER B 576 ? O SER C 579 
AB3 2 3 N PHE B 575 ? N PHE C 578 O TYR B 586 ? O TYR C 589 
AB4 1 2 N ILE B 712 ? N ILE C 715 O VAL B 762 ? O VAL C 765 
AB4 2 3 O PHE B 763 ? O PHE C 766 N LYS B 756 ? N LYS C 759 
# 
_pdbx_entry_details.entry_id                   8ZIU 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OD1 J ASP 159 ? ? "O3'" J ADP 401 ? ? 2.13 
2 1 OH  C TYR 554 ? ? O     C HIS 577 ? ? 2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS J 63  ? ? -94.79  32.57   
2  1 GLU J 74  ? ? -90.79  -60.57  
3  1 PRO J 245 ? ? -82.41  40.42   
4  1 ASP J 246 ? ? -143.53 28.18   
5  1 PRO J 266 ? ? -65.54  2.31    
6  1 GLU C 45  ? ? 68.75   -11.85  
7  1 ASN C 65  ? ? -140.95 33.24   
8  1 TYR C 128 ? ? 58.94   8.43    
9  1 PRO C 132 ? ? -80.38  45.29   
10 1 ASN C 135 ? ? -49.34  -72.19  
11 1 ALA C 141 ? ? -85.17  49.82   
12 1 ALA C 199 ? ? -96.67  57.49   
13 1 ARG C 238 ? ? -98.02  32.24   
14 1 ARG C 244 ? ? -94.58  30.30   
15 1 TYR C 267 ? ? -122.49 -165.46 
16 1 ARG C 370 ? ? 72.70   -3.52   
17 1 THR C 450 ? ? -160.30 110.00  
18 1 ASP C 523 ? ? -97.45  35.47   
19 1 PRO C 528 ? ? -74.81  42.69   
20 1 ASP C 600 ? ? -145.71 57.21   
21 1 ASP C 754 ? ? -175.94 -170.68 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZIU 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8ZIU 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.54 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               92110 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 'Mouse MYH6 R404Q left ventricle actin and myosin complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8ZIU 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8ZIU 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZIU 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 C VAL 51  ? B VAL 48  
2  1 Y 1 C VAL 52  ? B VAL 49  
3  1 Y 1 C SER 53  ? B SER 50  
4  1 Y 1 C ARG 54  ? B ARG 51  
5  1 Y 1 C GLU 55  ? B GLU 52  
6  1 Y 1 C GLY 56  ? B GLY 53  
7  1 Y 1 C GLY 57  ? B GLY 54  
8  1 Y 1 C LYS 58  ? B LYS 55  
9  1 Y 1 C VAL 59  ? B VAL 56  
10 1 Y 1 C THR 60  ? B THR 57  
11 1 Y 1 C ILE 201 ? B ILE 198 
12 1 Y 1 C GLY 202 ? B GLY 199 
13 1 Y 1 C ASP 203 ? B ASP 200 
14 1 Y 1 C ARG 204 ? B ARG 201 
15 1 Y 1 C SER 205 ? B SER 202 
16 1 Y 1 C LYS 206 ? B LYS 203 
17 1 Y 1 C LYS 207 ? B LYS 204 
18 1 Y 1 C GLU 208 ? B GLU 205 
19 1 Y 1 C ASN 209 ? B ASN 206 
20 1 Y 1 C PRO 210 ? B PRO 207 
21 1 Y 1 C ASN 211 ? B ASN 208 
22 1 Y 1 C ALA 212 ? B ALA 209 
23 1 Y 1 C ASN 213 ? B ASN 210 
24 1 Y 1 C LYS 214 ? B LYS 211 
25 1 Y 1 C TYR 625 ? B TYR 622 
26 1 Y 1 C ALA 626 ? B ALA 623 
27 1 Y 1 C SER 627 ? B SER 624 
28 1 Y 1 C ALA 628 ? B ALA 625 
29 1 Y 1 C ASP 629 ? B ASP 626 
30 1 Y 1 C THR 630 ? B THR 627 
31 1 Y 1 C GLY 631 ? B GLY 628 
32 1 Y 1 C ASP 632 ? B ASP 629 
33 1 Y 1 C SER 633 ? B SER 630 
34 1 Y 1 C GLY 634 ? B GLY 631 
35 1 Y 1 C LYS 635 ? B LYS 632 
36 1 Y 1 C GLY 636 ? B GLY 633 
37 1 Y 1 C GLY 638 ? B GLY 635 
38 1 Y 1 C GLY 639 ? B GLY 636 
39 1 Y 1 C LYS 640 ? B LYS 637 
40 1 Y 1 C LYS 641 ? B LYS 638 
41 1 Y 1 C LYS 642 ? B LYS 639 
42 1 Y 1 C GLY 643 ? B GLY 640 
43 1 Y 1 C ASN 728 ? B ASN 725 
44 1 Y 1 C PRO 729 ? B PRO 726 
45 1 Y 1 C ALA 730 ? B ALA 727 
46 1 Y 1 C ALA 731 ? B ALA 728 
47 1 Y 1 C ILE 732 ? B ILE 729 
48 1 Y 1 C PRO 733 ? B PRO 730 
49 1 Y 1 C GLU 734 ? B GLU 731 
50 1 Y 1 C GLY 735 ? B GLY 732 
51 1 Y 1 C GLN 736 ? B GLN 733 
52 1 Y 1 C PHE 737 ? B PHE 734 
53 1 Y 1 C ILE 738 ? B ILE 735 
54 1 Y 1 C ASP 739 ? B ASP 736 
55 1 Y 1 C SER 740 ? B SER 737 
56 1 Y 1 C ARG 741 ? B ARG 738 
57 1 Y 1 C LYS 742 ? B LYS 739 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ADP PB     P N N 1   
ADP O1B    O N N 2   
ADP O2B    O N N 3   
ADP O3B    O N N 4   
ADP PA     P N S 5   
ADP O1A    O N N 6   
ADP O2A    O N N 7   
ADP O3A    O N N 8   
ADP "O5'"  O N N 9   
ADP "C5'"  C N N 10  
ADP "C4'"  C N R 11  
ADP "O4'"  O N N 12  
ADP "C3'"  C N S 13  
ADP "O3'"  O N N 14  
ADP "C2'"  C N R 15  
ADP "O2'"  O N N 16  
ADP "C1'"  C N R 17  
ADP N9     N Y N 18  
ADP C8     C Y N 19  
ADP N7     N Y N 20  
ADP C5     C Y N 21  
ADP C6     C Y N 22  
ADP N6     N N N 23  
ADP N1     N Y N 24  
ADP C2     C Y N 25  
ADP N3     N Y N 26  
ADP C4     C Y N 27  
ADP HOB2   H N N 28  
ADP HOB3   H N N 29  
ADP HOA2   H N N 30  
ADP "H5'1" H N N 31  
ADP "H5'2" H N N 32  
ADP "H4'"  H N N 33  
ADP "H3'"  H N N 34  
ADP "HO3'" H N N 35  
ADP "H2'"  H N N 36  
ADP "HO2'" H N N 37  
ADP "H1'"  H N N 38  
ADP H8     H N N 39  
ADP HN61   H N N 40  
ADP HN62   H N N 41  
ADP H2     H N N 42  
ALA N      N N N 43  
ALA CA     C N S 44  
ALA C      C N N 45  
ALA O      O N N 46  
ALA CB     C N N 47  
ALA OXT    O N N 48  
ALA H      H N N 49  
ALA H2     H N N 50  
ALA HA     H N N 51  
ALA HB1    H N N 52  
ALA HB2    H N N 53  
ALA HB3    H N N 54  
ALA HXT    H N N 55  
ARG N      N N N 56  
ARG CA     C N S 57  
ARG C      C N N 58  
ARG O      O N N 59  
ARG CB     C N N 60  
ARG CG     C N N 61  
ARG CD     C N N 62  
ARG NE     N N N 63  
ARG CZ     C N N 64  
ARG NH1    N N N 65  
ARG NH2    N N N 66  
ARG OXT    O N N 67  
ARG H      H N N 68  
ARG H2     H N N 69  
ARG HA     H N N 70  
ARG HB2    H N N 71  
ARG HB3    H N N 72  
ARG HG2    H N N 73  
ARG HG3    H N N 74  
ARG HD2    H N N 75  
ARG HD3    H N N 76  
ARG HE     H N N 77  
ARG HH11   H N N 78  
ARG HH12   H N N 79  
ARG HH21   H N N 80  
ARG HH22   H N N 81  
ARG HXT    H N N 82  
ASN N      N N N 83  
ASN CA     C N S 84  
ASN C      C N N 85  
ASN O      O N N 86  
ASN CB     C N N 87  
ASN CG     C N N 88  
ASN OD1    O N N 89  
ASN ND2    N N N 90  
ASN OXT    O N N 91  
ASN H      H N N 92  
ASN H2     H N N 93  
ASN HA     H N N 94  
ASN HB2    H N N 95  
ASN HB3    H N N 96  
ASN HD21   H N N 97  
ASN HD22   H N N 98  
ASN HXT    H N N 99  
ASP N      N N N 100 
ASP CA     C N S 101 
ASP C      C N N 102 
ASP O      O N N 103 
ASP CB     C N N 104 
ASP CG     C N N 105 
ASP OD1    O N N 106 
ASP OD2    O N N 107 
ASP OXT    O N N 108 
ASP H      H N N 109 
ASP H2     H N N 110 
ASP HA     H N N 111 
ASP HB2    H N N 112 
ASP HB3    H N N 113 
ASP HD2    H N N 114 
ASP HXT    H N N 115 
CYS N      N N N 116 
CYS CA     C N R 117 
CYS C      C N N 118 
CYS O      O N N 119 
CYS CB     C N N 120 
CYS SG     S N N 121 
CYS OXT    O N N 122 
CYS H      H N N 123 
CYS H2     H N N 124 
CYS HA     H N N 125 
CYS HB2    H N N 126 
CYS HB3    H N N 127 
CYS HG     H N N 128 
CYS HXT    H N N 129 
GLN N      N N N 130 
GLN CA     C N S 131 
GLN C      C N N 132 
GLN O      O N N 133 
GLN CB     C N N 134 
GLN CG     C N N 135 
GLN CD     C N N 136 
GLN OE1    O N N 137 
GLN NE2    N N N 138 
GLN OXT    O N N 139 
GLN H      H N N 140 
GLN H2     H N N 141 
GLN HA     H N N 142 
GLN HB2    H N N 143 
GLN HB3    H N N 144 
GLN HG2    H N N 145 
GLN HG3    H N N 146 
GLN HE21   H N N 147 
GLN HE22   H N N 148 
GLN HXT    H N N 149 
GLU N      N N N 150 
GLU CA     C N S 151 
GLU C      C N N 152 
GLU O      O N N 153 
GLU CB     C N N 154 
GLU CG     C N N 155 
GLU CD     C N N 156 
GLU OE1    O N N 157 
GLU OE2    O N N 158 
GLU OXT    O N N 159 
GLU H      H N N 160 
GLU H2     H N N 161 
GLU HA     H N N 162 
GLU HB2    H N N 163 
GLU HB3    H N N 164 
GLU HG2    H N N 165 
GLU HG3    H N N 166 
GLU HE2    H N N 167 
GLU HXT    H N N 168 
GLY N      N N N 169 
GLY CA     C N N 170 
GLY C      C N N 171 
GLY O      O N N 172 
GLY OXT    O N N 173 
GLY H      H N N 174 
GLY H2     H N N 175 
GLY HA2    H N N 176 
GLY HA3    H N N 177 
GLY HXT    H N N 178 
HIS N      N N N 179 
HIS CA     C N S 180 
HIS C      C N N 181 
HIS O      O N N 182 
HIS CB     C N N 183 
HIS CG     C Y N 184 
HIS ND1    N Y N 185 
HIS CD2    C Y N 186 
HIS CE1    C Y N 187 
HIS NE2    N Y N 188 
HIS OXT    O N N 189 
HIS H      H N N 190 
HIS H2     H N N 191 
HIS HA     H N N 192 
HIS HB2    H N N 193 
HIS HB3    H N N 194 
HIS HD1    H N N 195 
HIS HD2    H N N 196 
HIS HE1    H N N 197 
HIS HE2    H N N 198 
HIS HXT    H N N 199 
ILE N      N N N 200 
ILE CA     C N S 201 
ILE C      C N N 202 
ILE O      O N N 203 
ILE CB     C N S 204 
ILE CG1    C N N 205 
ILE CG2    C N N 206 
ILE CD1    C N N 207 
ILE OXT    O N N 208 
ILE H      H N N 209 
ILE H2     H N N 210 
ILE HA     H N N 211 
ILE HB     H N N 212 
ILE HG12   H N N 213 
ILE HG13   H N N 214 
ILE HG21   H N N 215 
ILE HG22   H N N 216 
ILE HG23   H N N 217 
ILE HD11   H N N 218 
ILE HD12   H N N 219 
ILE HD13   H N N 220 
ILE HXT    H N N 221 
LEU N      N N N 222 
LEU CA     C N S 223 
LEU C      C N N 224 
LEU O      O N N 225 
LEU CB     C N N 226 
LEU CG     C N N 227 
LEU CD1    C N N 228 
LEU CD2    C N N 229 
LEU OXT    O N N 230 
LEU H      H N N 231 
LEU H2     H N N 232 
LEU HA     H N N 233 
LEU HB2    H N N 234 
LEU HB3    H N N 235 
LEU HG     H N N 236 
LEU HD11   H N N 237 
LEU HD12   H N N 238 
LEU HD13   H N N 239 
LEU HD21   H N N 240 
LEU HD22   H N N 241 
LEU HD23   H N N 242 
LEU HXT    H N N 243 
LYS N      N N N 244 
LYS CA     C N S 245 
LYS C      C N N 246 
LYS O      O N N 247 
LYS CB     C N N 248 
LYS CG     C N N 249 
LYS CD     C N N 250 
LYS CE     C N N 251 
LYS NZ     N N N 252 
LYS OXT    O N N 253 
LYS H      H N N 254 
LYS H2     H N N 255 
LYS HA     H N N 256 
LYS HB2    H N N 257 
LYS HB3    H N N 258 
LYS HG2    H N N 259 
LYS HG3    H N N 260 
LYS HD2    H N N 261 
LYS HD3    H N N 262 
LYS HE2    H N N 263 
LYS HE3    H N N 264 
LYS HZ1    H N N 265 
LYS HZ2    H N N 266 
LYS HZ3    H N N 267 
LYS HXT    H N N 268 
MET N      N N N 269 
MET CA     C N S 270 
MET C      C N N 271 
MET O      O N N 272 
MET CB     C N N 273 
MET CG     C N N 274 
MET SD     S N N 275 
MET CE     C N N 276 
MET OXT    O N N 277 
MET H      H N N 278 
MET H2     H N N 279 
MET HA     H N N 280 
MET HB2    H N N 281 
MET HB3    H N N 282 
MET HG2    H N N 283 
MET HG3    H N N 284 
MET HE1    H N N 285 
MET HE2    H N N 286 
MET HE3    H N N 287 
MET HXT    H N N 288 
PHE N      N N N 289 
PHE CA     C N S 290 
PHE C      C N N 291 
PHE O      O N N 292 
PHE CB     C N N 293 
PHE CG     C Y N 294 
PHE CD1    C Y N 295 
PHE CD2    C Y N 296 
PHE CE1    C Y N 297 
PHE CE2    C Y N 298 
PHE CZ     C Y N 299 
PHE OXT    O N N 300 
PHE H      H N N 301 
PHE H2     H N N 302 
PHE HA     H N N 303 
PHE HB2    H N N 304 
PHE HB3    H N N 305 
PHE HD1    H N N 306 
PHE HD2    H N N 307 
PHE HE1    H N N 308 
PHE HE2    H N N 309 
PHE HZ     H N N 310 
PHE HXT    H N N 311 
PRO N      N N N 312 
PRO CA     C N S 313 
PRO C      C N N 314 
PRO O      O N N 315 
PRO CB     C N N 316 
PRO CG     C N N 317 
PRO CD     C N N 318 
PRO OXT    O N N 319 
PRO H      H N N 320 
PRO HA     H N N 321 
PRO HB2    H N N 322 
PRO HB3    H N N 323 
PRO HG2    H N N 324 
PRO HG3    H N N 325 
PRO HD2    H N N 326 
PRO HD3    H N N 327 
PRO HXT    H N N 328 
SER N      N N N 329 
SER CA     C N S 330 
SER C      C N N 331 
SER O      O N N 332 
SER CB     C N N 333 
SER OG     O N N 334 
SER OXT    O N N 335 
SER H      H N N 336 
SER H2     H N N 337 
SER HA     H N N 338 
SER HB2    H N N 339 
SER HB3    H N N 340 
SER HG     H N N 341 
SER HXT    H N N 342 
THR N      N N N 343 
THR CA     C N S 344 
THR C      C N N 345 
THR O      O N N 346 
THR CB     C N R 347 
THR OG1    O N N 348 
THR CG2    C N N 349 
THR OXT    O N N 350 
THR H      H N N 351 
THR H2     H N N 352 
THR HA     H N N 353 
THR HB     H N N 354 
THR HG1    H N N 355 
THR HG21   H N N 356 
THR HG22   H N N 357 
THR HG23   H N N 358 
THR HXT    H N N 359 
TRP N      N N N 360 
TRP CA     C N S 361 
TRP C      C N N 362 
TRP O      O N N 363 
TRP CB     C N N 364 
TRP CG     C Y N 365 
TRP CD1    C Y N 366 
TRP CD2    C Y N 367 
TRP NE1    N Y N 368 
TRP CE2    C Y N 369 
TRP CE3    C Y N 370 
TRP CZ2    C Y N 371 
TRP CZ3    C Y N 372 
TRP CH2    C Y N 373 
TRP OXT    O N N 374 
TRP H      H N N 375 
TRP H2     H N N 376 
TRP HA     H N N 377 
TRP HB2    H N N 378 
TRP HB3    H N N 379 
TRP HD1    H N N 380 
TRP HE1    H N N 381 
TRP HE3    H N N 382 
TRP HZ2    H N N 383 
TRP HZ3    H N N 384 
TRP HH2    H N N 385 
TRP HXT    H N N 386 
TYR N      N N N 387 
TYR CA     C N S 388 
TYR C      C N N 389 
TYR O      O N N 390 
TYR CB     C N N 391 
TYR CG     C Y N 392 
TYR CD1    C Y N 393 
TYR CD2    C Y N 394 
TYR CE1    C Y N 395 
TYR CE2    C Y N 396 
TYR CZ     C Y N 397 
TYR OH     O N N 398 
TYR OXT    O N N 399 
TYR H      H N N 400 
TYR H2     H N N 401 
TYR HA     H N N 402 
TYR HB2    H N N 403 
TYR HB3    H N N 404 
TYR HD1    H N N 405 
TYR HD2    H N N 406 
TYR HE1    H N N 407 
TYR HE2    H N N 408 
TYR HH     H N N 409 
TYR HXT    H N N 410 
VAL N      N N N 411 
VAL CA     C N S 412 
VAL C      C N N 413 
VAL O      O N N 414 
VAL CB     C N N 415 
VAL CG1    C N N 416 
VAL CG2    C N N 417 
VAL OXT    O N N 418 
VAL H      H N N 419 
VAL H2     H N N 420 
VAL HA     H N N 421 
VAL HB     H N N 422 
VAL HG11   H N N 423 
VAL HG12   H N N 424 
VAL HG13   H N N 425 
VAL HG21   H N N 426 
VAL HG22   H N N 427 
VAL HG23   H N N 428 
VAL HXT    H N N 429 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ADP PB    O1B    doub N N 1   
ADP PB    O2B    sing N N 2   
ADP PB    O3B    sing N N 3   
ADP PB    O3A    sing N N 4   
ADP O2B   HOB2   sing N N 5   
ADP O3B   HOB3   sing N N 6   
ADP PA    O1A    doub N N 7   
ADP PA    O2A    sing N N 8   
ADP PA    O3A    sing N N 9   
ADP PA    "O5'"  sing N N 10  
ADP O2A   HOA2   sing N N 11  
ADP "O5'" "C5'"  sing N N 12  
ADP "C5'" "C4'"  sing N N 13  
ADP "C5'" "H5'1" sing N N 14  
ADP "C5'" "H5'2" sing N N 15  
ADP "C4'" "O4'"  sing N N 16  
ADP "C4'" "C3'"  sing N N 17  
ADP "C4'" "H4'"  sing N N 18  
ADP "O4'" "C1'"  sing N N 19  
ADP "C3'" "O3'"  sing N N 20  
ADP "C3'" "C2'"  sing N N 21  
ADP "C3'" "H3'"  sing N N 22  
ADP "O3'" "HO3'" sing N N 23  
ADP "C2'" "O2'"  sing N N 24  
ADP "C2'" "C1'"  sing N N 25  
ADP "C2'" "H2'"  sing N N 26  
ADP "O2'" "HO2'" sing N N 27  
ADP "C1'" N9     sing N N 28  
ADP "C1'" "H1'"  sing N N 29  
ADP N9    C8     sing Y N 30  
ADP N9    C4     sing Y N 31  
ADP C8    N7     doub Y N 32  
ADP C8    H8     sing N N 33  
ADP N7    C5     sing Y N 34  
ADP C5    C6     sing Y N 35  
ADP C5    C4     doub Y N 36  
ADP C6    N6     sing N N 37  
ADP C6    N1     doub Y N 38  
ADP N6    HN61   sing N N 39  
ADP N6    HN62   sing N N 40  
ADP N1    C2     sing Y N 41  
ADP C2    N3     doub Y N 42  
ADP C2    H2     sing N N 43  
ADP N3    C4     sing Y N 44  
ALA N     CA     sing N N 45  
ALA N     H      sing N N 46  
ALA N     H2     sing N N 47  
ALA CA    C      sing N N 48  
ALA CA    CB     sing N N 49  
ALA CA    HA     sing N N 50  
ALA C     O      doub N N 51  
ALA C     OXT    sing N N 52  
ALA CB    HB1    sing N N 53  
ALA CB    HB2    sing N N 54  
ALA CB    HB3    sing N N 55  
ALA OXT   HXT    sing N N 56  
ARG N     CA     sing N N 57  
ARG N     H      sing N N 58  
ARG N     H2     sing N N 59  
ARG CA    C      sing N N 60  
ARG CA    CB     sing N N 61  
ARG CA    HA     sing N N 62  
ARG C     O      doub N N 63  
ARG C     OXT    sing N N 64  
ARG CB    CG     sing N N 65  
ARG CB    HB2    sing N N 66  
ARG CB    HB3    sing N N 67  
ARG CG    CD     sing N N 68  
ARG CG    HG2    sing N N 69  
ARG CG    HG3    sing N N 70  
ARG CD    NE     sing N N 71  
ARG CD    HD2    sing N N 72  
ARG CD    HD3    sing N N 73  
ARG NE    CZ     sing N N 74  
ARG NE    HE     sing N N 75  
ARG CZ    NH1    sing N N 76  
ARG CZ    NH2    doub N N 77  
ARG NH1   HH11   sing N N 78  
ARG NH1   HH12   sing N N 79  
ARG NH2   HH21   sing N N 80  
ARG NH2   HH22   sing N N 81  
ARG OXT   HXT    sing N N 82  
ASN N     CA     sing N N 83  
ASN N     H      sing N N 84  
ASN N     H2     sing N N 85  
ASN CA    C      sing N N 86  
ASN CA    CB     sing N N 87  
ASN CA    HA     sing N N 88  
ASN C     O      doub N N 89  
ASN C     OXT    sing N N 90  
ASN CB    CG     sing N N 91  
ASN CB    HB2    sing N N 92  
ASN CB    HB3    sing N N 93  
ASN CG    OD1    doub N N 94  
ASN CG    ND2    sing N N 95  
ASN ND2   HD21   sing N N 96  
ASN ND2   HD22   sing N N 97  
ASN OXT   HXT    sing N N 98  
ASP N     CA     sing N N 99  
ASP N     H      sing N N 100 
ASP N     H2     sing N N 101 
ASP CA    C      sing N N 102 
ASP CA    CB     sing N N 103 
ASP CA    HA     sing N N 104 
ASP C     O      doub N N 105 
ASP C     OXT    sing N N 106 
ASP CB    CG     sing N N 107 
ASP CB    HB2    sing N N 108 
ASP CB    HB3    sing N N 109 
ASP CG    OD1    doub N N 110 
ASP CG    OD2    sing N N 111 
ASP OD2   HD2    sing N N 112 
ASP OXT   HXT    sing N N 113 
CYS N     CA     sing N N 114 
CYS N     H      sing N N 115 
CYS N     H2     sing N N 116 
CYS CA    C      sing N N 117 
CYS CA    CB     sing N N 118 
CYS CA    HA     sing N N 119 
CYS C     O      doub N N 120 
CYS C     OXT    sing N N 121 
CYS CB    SG     sing N N 122 
CYS CB    HB2    sing N N 123 
CYS CB    HB3    sing N N 124 
CYS SG    HG     sing N N 125 
CYS OXT   HXT    sing N N 126 
GLN N     CA     sing N N 127 
GLN N     H      sing N N 128 
GLN N     H2     sing N N 129 
GLN CA    C      sing N N 130 
GLN CA    CB     sing N N 131 
GLN CA    HA     sing N N 132 
GLN C     O      doub N N 133 
GLN C     OXT    sing N N 134 
GLN CB    CG     sing N N 135 
GLN CB    HB2    sing N N 136 
GLN CB    HB3    sing N N 137 
GLN CG    CD     sing N N 138 
GLN CG    HG2    sing N N 139 
GLN CG    HG3    sing N N 140 
GLN CD    OE1    doub N N 141 
GLN CD    NE2    sing N N 142 
GLN NE2   HE21   sing N N 143 
GLN NE2   HE22   sing N N 144 
GLN OXT   HXT    sing N N 145 
GLU N     CA     sing N N 146 
GLU N     H      sing N N 147 
GLU N     H2     sing N N 148 
GLU CA    C      sing N N 149 
GLU CA    CB     sing N N 150 
GLU CA    HA     sing N N 151 
GLU C     O      doub N N 152 
GLU C     OXT    sing N N 153 
GLU CB    CG     sing N N 154 
GLU CB    HB2    sing N N 155 
GLU CB    HB3    sing N N 156 
GLU CG    CD     sing N N 157 
GLU CG    HG2    sing N N 158 
GLU CG    HG3    sing N N 159 
GLU CD    OE1    doub N N 160 
GLU CD    OE2    sing N N 161 
GLU OE2   HE2    sing N N 162 
GLU OXT   HXT    sing N N 163 
GLY N     CA     sing N N 164 
GLY N     H      sing N N 165 
GLY N     H2     sing N N 166 
GLY CA    C      sing N N 167 
GLY CA    HA2    sing N N 168 
GLY CA    HA3    sing N N 169 
GLY C     O      doub N N 170 
GLY C     OXT    sing N N 171 
GLY OXT   HXT    sing N N 172 
HIS N     CA     sing N N 173 
HIS N     H      sing N N 174 
HIS N     H2     sing N N 175 
HIS CA    C      sing N N 176 
HIS CA    CB     sing N N 177 
HIS CA    HA     sing N N 178 
HIS C     O      doub N N 179 
HIS C     OXT    sing N N 180 
HIS CB    CG     sing N N 181 
HIS CB    HB2    sing N N 182 
HIS CB    HB3    sing N N 183 
HIS CG    ND1    sing Y N 184 
HIS CG    CD2    doub Y N 185 
HIS ND1   CE1    doub Y N 186 
HIS ND1   HD1    sing N N 187 
HIS CD2   NE2    sing Y N 188 
HIS CD2   HD2    sing N N 189 
HIS CE1   NE2    sing Y N 190 
HIS CE1   HE1    sing N N 191 
HIS NE2   HE2    sing N N 192 
HIS OXT   HXT    sing N N 193 
ILE N     CA     sing N N 194 
ILE N     H      sing N N 195 
ILE N     H2     sing N N 196 
ILE CA    C      sing N N 197 
ILE CA    CB     sing N N 198 
ILE CA    HA     sing N N 199 
ILE C     O      doub N N 200 
ILE C     OXT    sing N N 201 
ILE CB    CG1    sing N N 202 
ILE CB    CG2    sing N N 203 
ILE CB    HB     sing N N 204 
ILE CG1   CD1    sing N N 205 
ILE CG1   HG12   sing N N 206 
ILE CG1   HG13   sing N N 207 
ILE CG2   HG21   sing N N 208 
ILE CG2   HG22   sing N N 209 
ILE CG2   HG23   sing N N 210 
ILE CD1   HD11   sing N N 211 
ILE CD1   HD12   sing N N 212 
ILE CD1   HD13   sing N N 213 
ILE OXT   HXT    sing N N 214 
LEU N     CA     sing N N 215 
LEU N     H      sing N N 216 
LEU N     H2     sing N N 217 
LEU CA    C      sing N N 218 
LEU CA    CB     sing N N 219 
LEU CA    HA     sing N N 220 
LEU C     O      doub N N 221 
LEU C     OXT    sing N N 222 
LEU CB    CG     sing N N 223 
LEU CB    HB2    sing N N 224 
LEU CB    HB3    sing N N 225 
LEU CG    CD1    sing N N 226 
LEU CG    CD2    sing N N 227 
LEU CG    HG     sing N N 228 
LEU CD1   HD11   sing N N 229 
LEU CD1   HD12   sing N N 230 
LEU CD1   HD13   sing N N 231 
LEU CD2   HD21   sing N N 232 
LEU CD2   HD22   sing N N 233 
LEU CD2   HD23   sing N N 234 
LEU OXT   HXT    sing N N 235 
LYS N     CA     sing N N 236 
LYS N     H      sing N N 237 
LYS N     H2     sing N N 238 
LYS CA    C      sing N N 239 
LYS CA    CB     sing N N 240 
LYS CA    HA     sing N N 241 
LYS C     O      doub N N 242 
LYS C     OXT    sing N N 243 
LYS CB    CG     sing N N 244 
LYS CB    HB2    sing N N 245 
LYS CB    HB3    sing N N 246 
LYS CG    CD     sing N N 247 
LYS CG    HG2    sing N N 248 
LYS CG    HG3    sing N N 249 
LYS CD    CE     sing N N 250 
LYS CD    HD2    sing N N 251 
LYS CD    HD3    sing N N 252 
LYS CE    NZ     sing N N 253 
LYS CE    HE2    sing N N 254 
LYS CE    HE3    sing N N 255 
LYS NZ    HZ1    sing N N 256 
LYS NZ    HZ2    sing N N 257 
LYS NZ    HZ3    sing N N 258 
LYS OXT   HXT    sing N N 259 
MET N     CA     sing N N 260 
MET N     H      sing N N 261 
MET N     H2     sing N N 262 
MET CA    C      sing N N 263 
MET CA    CB     sing N N 264 
MET CA    HA     sing N N 265 
MET C     O      doub N N 266 
MET C     OXT    sing N N 267 
MET CB    CG     sing N N 268 
MET CB    HB2    sing N N 269 
MET CB    HB3    sing N N 270 
MET CG    SD     sing N N 271 
MET CG    HG2    sing N N 272 
MET CG    HG3    sing N N 273 
MET SD    CE     sing N N 274 
MET CE    HE1    sing N N 275 
MET CE    HE2    sing N N 276 
MET CE    HE3    sing N N 277 
MET OXT   HXT    sing N N 278 
PHE N     CA     sing N N 279 
PHE N     H      sing N N 280 
PHE N     H2     sing N N 281 
PHE CA    C      sing N N 282 
PHE CA    CB     sing N N 283 
PHE CA    HA     sing N N 284 
PHE C     O      doub N N 285 
PHE C     OXT    sing N N 286 
PHE CB    CG     sing N N 287 
PHE CB    HB2    sing N N 288 
PHE CB    HB3    sing N N 289 
PHE CG    CD1    doub Y N 290 
PHE CG    CD2    sing Y N 291 
PHE CD1   CE1    sing Y N 292 
PHE CD1   HD1    sing N N 293 
PHE CD2   CE2    doub Y N 294 
PHE CD2   HD2    sing N N 295 
PHE CE1   CZ     doub Y N 296 
PHE CE1   HE1    sing N N 297 
PHE CE2   CZ     sing Y N 298 
PHE CE2   HE2    sing N N 299 
PHE CZ    HZ     sing N N 300 
PHE OXT   HXT    sing N N 301 
PRO N     CA     sing N N 302 
PRO N     CD     sing N N 303 
PRO N     H      sing N N 304 
PRO CA    C      sing N N 305 
PRO CA    CB     sing N N 306 
PRO CA    HA     sing N N 307 
PRO C     O      doub N N 308 
PRO C     OXT    sing N N 309 
PRO CB    CG     sing N N 310 
PRO CB    HB2    sing N N 311 
PRO CB    HB3    sing N N 312 
PRO CG    CD     sing N N 313 
PRO CG    HG2    sing N N 314 
PRO CG    HG3    sing N N 315 
PRO CD    HD2    sing N N 316 
PRO CD    HD3    sing N N 317 
PRO OXT   HXT    sing N N 318 
SER N     CA     sing N N 319 
SER N     H      sing N N 320 
SER N     H2     sing N N 321 
SER CA    C      sing N N 322 
SER CA    CB     sing N N 323 
SER CA    HA     sing N N 324 
SER C     O      doub N N 325 
SER C     OXT    sing N N 326 
SER CB    OG     sing N N 327 
SER CB    HB2    sing N N 328 
SER CB    HB3    sing N N 329 
SER OG    HG     sing N N 330 
SER OXT   HXT    sing N N 331 
THR N     CA     sing N N 332 
THR N     H      sing N N 333 
THR N     H2     sing N N 334 
THR CA    C      sing N N 335 
THR CA    CB     sing N N 336 
THR CA    HA     sing N N 337 
THR C     O      doub N N 338 
THR C     OXT    sing N N 339 
THR CB    OG1    sing N N 340 
THR CB    CG2    sing N N 341 
THR CB    HB     sing N N 342 
THR OG1   HG1    sing N N 343 
THR CG2   HG21   sing N N 344 
THR CG2   HG22   sing N N 345 
THR CG2   HG23   sing N N 346 
THR OXT   HXT    sing N N 347 
TRP N     CA     sing N N 348 
TRP N     H      sing N N 349 
TRP N     H2     sing N N 350 
TRP CA    C      sing N N 351 
TRP CA    CB     sing N N 352 
TRP CA    HA     sing N N 353 
TRP C     O      doub N N 354 
TRP C     OXT    sing N N 355 
TRP CB    CG     sing N N 356 
TRP CB    HB2    sing N N 357 
TRP CB    HB3    sing N N 358 
TRP CG    CD1    doub Y N 359 
TRP CG    CD2    sing Y N 360 
TRP CD1   NE1    sing Y N 361 
TRP CD1   HD1    sing N N 362 
TRP CD2   CE2    doub Y N 363 
TRP CD2   CE3    sing Y N 364 
TRP NE1   CE2    sing Y N 365 
TRP NE1   HE1    sing N N 366 
TRP CE2   CZ2    sing Y N 367 
TRP CE3   CZ3    doub Y N 368 
TRP CE3   HE3    sing N N 369 
TRP CZ2   CH2    doub Y N 370 
TRP CZ2   HZ2    sing N N 371 
TRP CZ3   CH2    sing Y N 372 
TRP CZ3   HZ3    sing N N 373 
TRP CH2   HH2    sing N N 374 
TRP OXT   HXT    sing N N 375 
TYR N     CA     sing N N 376 
TYR N     H      sing N N 377 
TYR N     H2     sing N N 378 
TYR CA    C      sing N N 379 
TYR CA    CB     sing N N 380 
TYR CA    HA     sing N N 381 
TYR C     O      doub N N 382 
TYR C     OXT    sing N N 383 
TYR CB    CG     sing N N 384 
TYR CB    HB2    sing N N 385 
TYR CB    HB3    sing N N 386 
TYR CG    CD1    doub Y N 387 
TYR CG    CD2    sing Y N 388 
TYR CD1   CE1    sing Y N 389 
TYR CD1   HD1    sing N N 390 
TYR CD2   CE2    doub Y N 391 
TYR CD2   HD2    sing N N 392 
TYR CE1   CZ     doub Y N 393 
TYR CE1   HE1    sing N N 394 
TYR CE2   CZ     sing Y N 395 
TYR CE2   HE2    sing N N 396 
TYR CZ    OH     sing N N 397 
TYR OH    HH     sing N N 398 
TYR OXT   HXT    sing N N 399 
VAL N     CA     sing N N 400 
VAL N     H      sing N N 401 
VAL N     H2     sing N N 402 
VAL CA    C      sing N N 403 
VAL CA    CB     sing N N 404 
VAL CA    HA     sing N N 405 
VAL C     O      doub N N 406 
VAL C     OXT    sing N N 407 
VAL CB    CG1    sing N N 408 
VAL CB    CG2    sing N N 409 
VAL CB    HB     sing N N 410 
VAL CG1   HG11   sing N N 411 
VAL CG1   HG12   sing N N 412 
VAL CG1   HG13   sing N N 413 
VAL CG2   HG21   sing N N 414 
VAL CG2   HG22   sing N N 415 
VAL CG2   HG23   sing N N 416 
VAL OXT   HXT    sing N N 417 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-14 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZIU 
_em_admin.last_update        2025-01-29 
_em_admin.map_release_date   2025-01-29 
_em_admin.title              'Mouse MYH6 R404Q left ventricle actin and myosin complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10090 
_em_entity_assembly_naturalsource.organism             'Mus musculus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         55 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOCONTINUUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.15.2_3472: 
'IMAGE ACQUISITION'        ? 3  1 1 1 ?      ?            
MASKING                    ? 4  1 1 1 ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  1 1 1 ?      ?            
'DIFFRACTION INDEXING'     ? 7  1 1 1 ?      ?            
'MODEL FITTING'            ? 8  1 1 1 ?      ?            
OTHER                      ? 9  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8ZIU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . THR A 1 1   ? 240.823 188.195 222.000 1.00 75.90  ? 7   THR J N     1 
ATOM   2    C CA    . THR A 1 1   ? 240.005 188.795 223.048 1.00 75.90  ? 7   THR J CA    1 
ATOM   3    C C     . THR A 1 1   ? 238.532 188.432 222.861 1.00 75.90  ? 7   THR J C     1 
ATOM   4    O O     . THR A 1 1   ? 238.010 188.450 221.746 1.00 75.90  ? 7   THR J O     1 
ATOM   5    C CB    . THR A 1 1   ? 240.180 190.336 223.088 1.00 75.90  ? 7   THR J CB    1 
ATOM   6    O OG1   . THR A 1 1   ? 239.386 190.889 224.145 1.00 75.90  ? 7   THR J OG1   1 
ATOM   7    C CG2   . THR A 1 1   ? 239.792 190.977 221.758 1.00 75.90  ? 7   THR J CG2   1 
ATOM   8    N N     . THR A 1 2   ? 237.873 188.077 223.959 1.00 69.86  ? 8   THR J N     1 
ATOM   9    C CA    . THR A 1 2   ? 236.481 187.664 223.900 1.00 69.86  ? 8   THR J CA    1 
ATOM   10   C C     . THR A 1 2   ? 235.557 188.876 223.923 1.00 69.86  ? 8   THR J C     1 
ATOM   11   O O     . THR A 1 2   ? 235.963 189.998 224.233 1.00 69.86  ? 8   THR J O     1 
ATOM   12   C CB    . THR A 1 2   ? 236.143 186.732 225.062 1.00 69.86  ? 8   THR J CB    1 
ATOM   13   O OG1   . THR A 1 2   ? 236.594 187.314 226.290 1.00 69.86  ? 8   THR J OG1   1 
ATOM   14   C CG2   . THR A 1 2   ? 236.814 185.382 224.873 1.00 69.86  ? 8   THR J CG2   1 
ATOM   15   N N     . ALA A 1 3   ? 234.297 188.636 223.585 1.00 60.47  ? 9   ALA J N     1 
ATOM   16   C CA    . ALA A 1 3   ? 233.271 189.663 223.607 1.00 60.47  ? 9   ALA J CA    1 
ATOM   17   C C     . ALA A 1 3   ? 232.236 189.347 224.677 1.00 60.47  ? 9   ALA J C     1 
ATOM   18   O O     . ALA A 1 3   ? 232.004 188.188 225.028 1.00 60.47  ? 9   ALA J O     1 
ATOM   19   C CB    . ALA A 1 3   ? 232.592 189.794 222.242 1.00 60.47  ? 9   ALA J CB    1 
ATOM   20   N N     . LEU A 1 4   ? 231.614 190.400 225.193 1.00 57.55  ? 10  LEU J N     1 
ATOM   21   C CA    . LEU A 1 4   ? 230.597 190.284 226.225 1.00 57.55  ? 10  LEU J CA    1 
ATOM   22   C C     . LEU A 1 4   ? 229.214 190.452 225.616 1.00 57.55  ? 10  LEU J C     1 
ATOM   23   O O     . LEU A 1 4   ? 229.002 191.311 224.758 1.00 57.55  ? 10  LEU J O     1 
ATOM   24   C CB    . LEU A 1 4   ? 230.803 191.333 227.318 1.00 57.55  ? 10  LEU J CB    1 
ATOM   25   C CG    . LEU A 1 4   ? 232.148 191.345 228.034 1.00 57.55  ? 10  LEU J CG    1 
ATOM   26   C CD1   . LEU A 1 4   ? 232.230 192.530 228.966 1.00 57.55  ? 10  LEU J CD1   1 
ATOM   27   C CD2   . LEU A 1 4   ? 232.342 190.058 228.797 1.00 57.55  ? 10  LEU J CD2   1 
ATOM   28   N N     . VAL A 1 5   ? 228.276 189.627 226.068 1.00 54.51  ? 11  VAL J N     1 
ATOM   29   C CA    . VAL A 1 5   ? 226.873 189.736 225.695 1.00 54.51  ? 11  VAL J CA    1 
ATOM   30   C C     . VAL A 1 5   ? 226.090 190.047 226.958 1.00 54.51  ? 11  VAL J C     1 
ATOM   31   O O     . VAL A 1 5   ? 226.173 189.305 227.941 1.00 54.51  ? 11  VAL J O     1 
ATOM   32   C CB    . VAL A 1 5   ? 226.360 188.452 225.024 1.00 54.51  ? 11  VAL J CB    1 
ATOM   33   C CG1   . VAL A 1 5   ? 224.972 188.671 224.463 1.00 54.51  ? 11  VAL J CG1   1 
ATOM   34   C CG2   . VAL A 1 5   ? 227.311 188.021 223.931 1.00 54.51  ? 11  VAL J CG2   1 
ATOM   35   N N     . CYS A 1 6   ? 225.336 191.137 226.931 1.00 57.95  ? 12  CYS J N     1 
ATOM   36   C CA    . CYS A 1 6   ? 224.729 191.720 228.121 1.00 57.95  ? 12  CYS J CA    1 
ATOM   37   C C     . CYS A 1 6   ? 223.253 191.999 227.884 1.00 57.95  ? 12  CYS J C     1 
ATOM   38   O O     . CYS A 1 6   ? 222.781 193.127 228.030 1.00 57.95  ? 12  CYS J O     1 
ATOM   39   C CB    . CYS A 1 6   ? 225.463 192.987 228.547 1.00 57.95  ? 12  CYS J CB    1 
ATOM   40   S SG    . CYS A 1 6   ? 224.897 193.694 230.114 1.00 57.95  ? 12  CYS J SG    1 
ATOM   41   N N     . ASP A 1 7   ? 222.513 190.980 227.446 1.00 58.41  ? 13  ASP J N     1 
ATOM   42   C CA    . ASP A 1 7   ? 221.079 191.126 227.229 1.00 58.41  ? 13  ASP J CA    1 
ATOM   43   C C     . ASP A 1 7   ? 220.416 191.707 228.470 1.00 58.41  ? 13  ASP J C     1 
ATOM   44   O O     . ASP A 1 7   ? 220.359 191.058 229.517 1.00 58.41  ? 13  ASP J O     1 
ATOM   45   C CB    . ASP A 1 7   ? 220.452 189.778 226.877 1.00 58.41  ? 13  ASP J CB    1 
ATOM   46   C CG    . ASP A 1 7   ? 218.950 189.853 226.739 1.00 58.41  ? 13  ASP J CG    1 
ATOM   47   O OD1   . ASP A 1 7   ? 218.430 190.951 226.464 1.00 58.41  ? 13  ASP J OD1   1 
ATOM   48   O OD2   . ASP A 1 7   ? 218.284 188.812 226.906 1.00 58.41  ? 13  ASP J OD2   1 
ATOM   49   N N     . ASN A 1 8   ? 219.894 192.926 228.349 1.00 59.45  ? 14  ASN J N     1 
ATOM   50   C CA    . ASN A 1 8   ? 219.481 193.682 229.525 1.00 59.45  ? 14  ASN J CA    1 
ATOM   51   C C     . ASN A 1 8   ? 218.159 193.175 230.082 1.00 59.45  ? 14  ASN J C     1 
ATOM   52   O O     . ASN A 1 8   ? 218.097 192.700 231.219 1.00 59.45  ? 14  ASN J O     1 
ATOM   53   C CB    . ASN A 1 8   ? 219.384 195.169 229.183 1.00 59.45  ? 14  ASN J CB    1 
ATOM   54   C CG    . ASN A 1 8   ? 220.728 195.775 228.849 1.00 59.45  ? 14  ASN J CG    1 
ATOM   55   O OD1   . ASN A 1 8   ? 220.976 196.175 227.713 1.00 59.45  ? 14  ASN J OD1   1 
ATOM   56   N ND2   . ASN A 1 8   ? 221.603 195.853 229.843 1.00 59.45  ? 14  ASN J ND2   1 
ATOM   57   N N     . GLY A 1 9   ? 217.088 193.284 229.303 1.00 59.30  ? 15  GLY J N     1 
ATOM   58   C CA    . GLY A 1 9   ? 215.781 192.882 229.780 1.00 59.30  ? 15  GLY J CA    1 
ATOM   59   C C     . GLY A 1 9   ? 215.260 193.812 230.854 1.00 59.30  ? 15  GLY J C     1 
ATOM   60   O O     . GLY A 1 9   ? 216.038 194.506 231.511 1.00 59.30  ? 15  GLY J O     1 
ATOM   61   N N     . SER A 1 10  ? 213.949 193.837 231.052 1.00 59.93  ? 16  SER J N     1 
ATOM   62   C CA    . SER A 1 10  ? 213.360 194.726 232.041 1.00 59.93  ? 16  SER J CA    1 
ATOM   63   C C     . SER A 1 10  ? 213.178 194.074 233.403 1.00 59.93  ? 16  SER J C     1 
ATOM   64   O O     . SER A 1 10  ? 212.802 194.765 234.354 1.00 59.93  ? 16  SER J O     1 
ATOM   65   C CB    . SER A 1 10  ? 212.011 195.245 231.542 1.00 59.93  ? 16  SER J CB    1 
ATOM   66   O OG    . SER A 1 10  ? 211.083 194.187 231.412 1.00 59.93  ? 16  SER J OG    1 
ATOM   67   N N     . GLY A 1 11  ? 213.429 192.775 233.524 1.00 59.31  ? 17  GLY J N     1 
ATOM   68   C CA    . GLY A 1 11  ? 213.228 192.100 234.789 1.00 59.31  ? 17  GLY J CA    1 
ATOM   69   C C     . GLY A 1 11  ? 214.341 191.155 235.185 1.00 59.31  ? 17  GLY J C     1 
ATOM   70   O O     . GLY A 1 11  ? 214.348 190.644 236.307 1.00 59.31  ? 17  GLY J O     1 
ATOM   71   N N     . LEU A 1 12  ? 215.291 190.920 234.284 1.00 57.05  ? 18  LEU J N     1 
ATOM   72   C CA    . LEU A 1 12  ? 216.391 189.998 234.552 1.00 57.05  ? 18  LEU J CA    1 
ATOM   73   C C     . LEU A 1 12  ? 217.562 190.374 233.665 1.00 57.05  ? 18  LEU J C     1 
ATOM   74   O O     . LEU A 1 12  ? 217.412 190.422 232.444 1.00 57.05  ? 18  LEU J O     1 
ATOM   75   C CB    . LEU A 1 12  ? 215.973 188.555 234.287 1.00 57.05  ? 18  LEU J CB    1 
ATOM   76   C CG    . LEU A 1 12  ? 215.273 187.759 235.382 1.00 57.05  ? 18  LEU J CG    1 
ATOM   77   C CD1   . LEU A 1 12  ? 214.931 186.376 234.875 1.00 57.05  ? 18  LEU J CD1   1 
ATOM   78   C CD2   . LEU A 1 12  ? 216.155 187.670 236.607 1.00 57.05  ? 18  LEU J CD2   1 
ATOM   79   N N     . VAL A 1 13  ? 218.720 190.618 234.264 1.00 55.47  ? 19  VAL J N     1 
ATOM   80   C CA    . VAL A 1 13  ? 219.937 190.891 233.512 1.00 55.47  ? 19  VAL J CA    1 
ATOM   81   C C     . VAL A 1 13  ? 220.675 189.580 233.286 1.00 55.47  ? 19  VAL J C     1 
ATOM   82   O O     . VAL A 1 13  ? 221.023 188.880 234.241 1.00 55.47  ? 19  VAL J O     1 
ATOM   83   C CB    . VAL A 1 13  ? 220.827 191.904 234.248 1.00 55.47  ? 19  VAL J CB    1 
ATOM   84   C CG1   . VAL A 1 13  ? 222.223 191.886 233.672 1.00 55.47  ? 19  VAL J CG1   1 
ATOM   85   C CG2   . VAL A 1 13  ? 220.239 193.290 234.139 1.00 55.47  ? 19  VAL J CG2   1 
ATOM   86   N N     . LYS A 1 14  ? 220.914 189.247 232.022 1.00 54.11  ? 20  LYS J N     1 
ATOM   87   C CA    . LYS A 1 14  ? 221.604 188.020 231.638 1.00 54.11  ? 20  LYS J CA    1 
ATOM   88   C C     . LYS A 1 14  ? 222.881 188.406 230.909 1.00 54.11  ? 20  LYS J C     1 
ATOM   89   O O     . LYS A 1 14  ? 222.826 188.956 229.806 1.00 54.11  ? 20  LYS J O     1 
ATOM   90   C CB    . LYS A 1 14  ? 220.715 187.146 230.759 1.00 54.11  ? 20  LYS J CB    1 
ATOM   91   C CG    . LYS A 1 14  ? 219.307 187.003 231.281 1.00 54.11  ? 20  LYS J CG    1 
ATOM   92   C CD    . LYS A 1 14  ? 218.424 186.277 230.297 1.00 54.11  ? 20  LYS J CD    1 
ATOM   93   C CE    . LYS A 1 14  ? 216.968 186.493 230.632 1.00 54.11  ? 20  LYS J CE    1 
ATOM   94   N NZ    . LYS A 1 14  ? 216.644 187.939 230.686 1.00 54.11  ? 20  LYS J NZ    1 
ATOM   95   N N     . ALA A 1 15  ? 224.024 188.123 231.520 1.00 54.89  ? 21  ALA J N     1 
ATOM   96   C CA    . ALA A 1 15  ? 225.314 188.471 230.953 1.00 54.89  ? 21  ALA J CA    1 
ATOM   97   C C     . ALA A 1 15  ? 226.172 187.225 230.791 1.00 54.89  ? 21  ALA J C     1 
ATOM   98   O O     . ALA A 1 15  ? 225.876 186.159 231.332 1.00 54.89  ? 21  ALA J O     1 
ATOM   99   C CB    . ALA A 1 15  ? 226.036 189.503 231.821 1.00 54.89  ? 21  ALA J CB    1 
ATOM   100  N N     . GLY A 1 16  ? 227.252 187.374 230.036 1.00 55.89  ? 22  GLY J N     1 
ATOM   101  C CA    . GLY A 1 16  ? 228.151 186.267 229.796 1.00 55.89  ? 22  GLY J CA    1 
ATOM   102  C C     . GLY A 1 16  ? 229.145 186.621 228.709 1.00 55.89  ? 22  GLY J C     1 
ATOM   103  O O     . GLY A 1 16  ? 229.218 187.763 228.257 1.00 55.89  ? 22  GLY J O     1 
ATOM   104  N N     . PHE A 1 17  ? 229.906 185.613 228.301 1.00 56.95  ? 23  PHE J N     1 
ATOM   105  C CA    . PHE A 1 17  ? 230.929 185.767 227.279 1.00 56.95  ? 23  PHE J CA    1 
ATOM   106  C C     . PHE A 1 17  ? 230.444 185.193 225.957 1.00 56.95  ? 23  PHE J C     1 
ATOM   107  O O     . PHE A 1 17  ? 229.879 184.098 225.914 1.00 56.95  ? 23  PHE J O     1 
ATOM   108  C CB    . PHE A 1 17  ? 232.224 185.074 227.696 1.00 56.95  ? 23  PHE J CB    1 
ATOM   109  C CG    . PHE A 1 17  ? 232.866 185.675 228.903 1.00 56.95  ? 23  PHE J CG    1 
ATOM   110  C CD1   . PHE A 1 17  ? 233.718 186.753 228.781 1.00 56.95  ? 23  PHE J CD1   1 
ATOM   111  C CD2   . PHE A 1 17  ? 232.617 185.165 230.161 1.00 56.95  ? 23  PHE J CD2   1 
ATOM   112  C CE1   . PHE A 1 17  ? 234.308 187.308 229.889 1.00 56.95  ? 23  PHE J CE1   1 
ATOM   113  C CE2   . PHE A 1 17  ? 233.205 185.717 231.274 1.00 56.95  ? 23  PHE J CE2   1 
ATOM   114  C CZ    . PHE A 1 17  ? 234.050 186.787 231.137 1.00 56.95  ? 23  PHE J CZ    1 
ATOM   115  N N     . ALA A 1 18  ? 230.670 185.940 224.882 1.00 54.66  ? 24  ALA J N     1 
ATOM   116  C CA    . ALA A 1 18  ? 230.306 185.474 223.552 1.00 54.66  ? 24  ALA J CA    1 
ATOM   117  C C     . ALA A 1 18  ? 231.057 184.193 223.228 1.00 54.66  ? 24  ALA J C     1 
ATOM   118  O O     . ALA A 1 18  ? 232.289 184.160 223.256 1.00 54.66  ? 24  ALA J O     1 
ATOM   119  C CB    . ALA A 1 18  ? 230.612 186.550 222.516 1.00 54.66  ? 24  ALA J CB    1 
ATOM   120  N N     . GLY A 1 19  ? 230.311 183.139 222.922 1.00 57.77  ? 25  GLY J N     1 
ATOM   121  C CA    . GLY A 1 19  ? 230.864 181.822 222.678 1.00 57.77  ? 25  GLY J CA    1 
ATOM   122  C C     . GLY A 1 19  ? 230.405 180.773 223.664 1.00 57.77  ? 25  GLY J C     1 
ATOM   123  O O     . GLY A 1 19  ? 230.453 179.577 223.348 1.00 57.77  ? 25  GLY J O     1 
ATOM   124  N N     . ASP A 1 20  ? 229.955 181.180 224.846 1.00 59.99  ? 26  ASP J N     1 
ATOM   125  C CA    . ASP A 1 20  ? 229.443 180.243 225.827 1.00 59.99  ? 26  ASP J CA    1 
ATOM   126  C C     . ASP A 1 20  ? 228.062 179.744 225.414 1.00 59.99  ? 26  ASP J C     1 
ATOM   127  O O     . ASP A 1 20  ? 227.387 180.320 224.559 1.00 59.99  ? 26  ASP J O     1 
ATOM   128  C CB    . ASP A 1 20  ? 229.380 180.892 227.207 1.00 59.99  ? 26  ASP J CB    1 
ATOM   129  C CG    . ASP A 1 20  ? 230.750 181.113 227.811 1.00 59.99  ? 26  ASP J CG    1 
ATOM   130  O OD1   . ASP A 1 20  ? 231.752 180.938 227.089 1.00 59.99  ? 26  ASP J OD1   1 
ATOM   131  O OD2   . ASP A 1 20  ? 230.827 181.461 229.008 1.00 59.99  ? 26  ASP J OD2   1 
ATOM   132  N N     . ASP A 1 21  ? 227.642 178.652 226.042 1.00 64.70  ? 27  ASP J N     1 
ATOM   133  C CA    . ASP A 1 21  ? 226.345 178.059 225.764 1.00 64.70  ? 27  ASP J CA    1 
ATOM   134  C C     . ASP A 1 21  ? 225.215 178.687 226.565 1.00 64.70  ? 27  ASP J C     1 
ATOM   135  O O     . ASP A 1 21  ? 224.047 178.449 226.245 1.00 64.70  ? 27  ASP J O     1 
ATOM   136  C CB    . ASP A 1 21  ? 226.382 176.555 226.048 1.00 64.70  ? 27  ASP J CB    1 
ATOM   137  C CG    . ASP A 1 21  ? 226.793 175.746 224.842 1.00 64.70  ? 27  ASP J CG    1 
ATOM   138  O OD1   . ASP A 1 21  ? 227.276 176.343 223.860 1.00 64.70  ? 27  ASP J OD1   1 
ATOM   139  O OD2   . ASP A 1 21  ? 226.629 174.509 224.875 1.00 64.70  ? 27  ASP J OD2   1 
ATOM   140  N N     . ALA A 1 22  ? 225.529 179.476 227.589 1.00 61.02  ? 28  ALA J N     1 
ATOM   141  C CA    . ALA A 1 22  ? 224.515 179.983 228.501 1.00 61.02  ? 28  ALA J CA    1 
ATOM   142  C C     . ALA A 1 22  ? 225.063 181.205 229.212 1.00 61.02  ? 28  ALA J C     1 
ATOM   143  O O     . ALA A 1 22  ? 226.279 181.313 229.399 1.00 61.02  ? 28  ALA J O     1 
ATOM   144  C CB    . ALA A 1 22  ? 224.112 178.916 229.522 1.00 61.02  ? 28  ALA J CB    1 
ATOM   145  N N     . PRO A 1 23  ? 224.204 182.136 229.617 1.00 58.08  ? 29  PRO J N     1 
ATOM   146  C CA    . PRO A 1 23  ? 224.685 183.300 230.365 1.00 58.08  ? 29  PRO J CA    1 
ATOM   147  C C     . PRO A 1 23  ? 225.251 182.888 231.710 1.00 58.08  ? 29  PRO J C     1 
ATOM   148  O O     . PRO A 1 23  ? 224.698 182.033 232.403 1.00 58.08  ? 29  PRO J O     1 
ATOM   149  C CB    . PRO A 1 23  ? 223.428 184.162 230.523 1.00 58.08  ? 29  PRO J CB    1 
ATOM   150  C CG    . PRO A 1 23  ? 222.302 183.211 230.380 1.00 58.08  ? 29  PRO J CG    1 
ATOM   151  C CD    . PRO A 1 23  ? 222.752 182.191 229.390 1.00 58.08  ? 29  PRO J CD    1 
ATOM   152  N N     . ARG A 1 24  ? 226.368 183.511 232.076 1.00 64.79  ? 30  ARG J N     1 
ATOM   153  C CA    . ARG A 1 24  ? 227.026 183.174 233.330 1.00 64.79  ? 30  ARG J CA    1 
ATOM   154  C C     . ARG A 1 24  ? 226.403 183.896 234.517 1.00 64.79  ? 30  ARG J C     1 
ATOM   155  O O     . ARG A 1 24  ? 226.356 183.338 235.618 1.00 64.79  ? 30  ARG J O     1 
ATOM   156  C CB    . ARG A 1 24  ? 228.519 183.490 233.234 1.00 64.79  ? 30  ARG J CB    1 
ATOM   157  C CG    . ARG A 1 24  ? 229.311 183.120 234.467 1.00 64.79  ? 30  ARG J CG    1 
ATOM   158  C CD    . ARG A 1 24  ? 230.796 183.277 234.233 1.00 64.79  ? 30  ARG J CD    1 
ATOM   159  N NE    . ARG A 1 24  ? 231.274 182.315 233.244 1.00 64.79  ? 30  ARG J NE    1 
ATOM   160  C CZ    . ARG A 1 24  ? 232.513 182.286 232.767 1.00 64.79  ? 30  ARG J CZ    1 
ATOM   161  N NH1   . ARG A 1 24  ? 233.414 183.158 233.199 1.00 64.79  ? 30  ARG J NH1   1 
ATOM   162  N NH2   . ARG A 1 24  ? 232.855 181.376 231.867 1.00 64.79  ? 30  ARG J NH2   1 
ATOM   163  N N     . ALA A 1 25  ? 225.917 185.117 234.319 1.00 57.67  ? 31  ALA J N     1 
ATOM   164  C CA    . ALA A 1 25  ? 225.327 185.917 235.385 1.00 57.67  ? 31  ALA J CA    1 
ATOM   165  C C     . ALA A 1 25  ? 223.876 186.212 235.043 1.00 57.67  ? 31  ALA J C     1 
ATOM   166  O O     . ALA A 1 25  ? 223.597 186.903 234.059 1.00 57.67  ? 31  ALA J O     1 
ATOM   167  C CB    . ALA A 1 25  ? 226.101 187.218 235.586 1.00 57.67  ? 31  ALA J CB    1 
ATOM   168  N N     . VAL A 1 26  ? 222.959 185.694 235.856 1.00 56.63  ? 32  VAL J N     1 
ATOM   169  C CA    . VAL A 1 26  ? 221.531 185.964 235.731 1.00 56.63  ? 32  VAL J CA    1 
ATOM   170  C C     . VAL A 1 26  ? 221.045 186.434 237.094 1.00 56.63  ? 32  VAL J C     1 
ATOM   171  O O     . VAL A 1 26  ? 221.064 185.664 238.060 1.00 56.63  ? 32  VAL J O     1 
ATOM   172  C CB    . VAL A 1 26  ? 220.741 184.735 235.267 1.00 56.63  ? 32  VAL J CB    1 
ATOM   173  C CG1   . VAL A 1 26  ? 219.284 185.085 235.088 1.00 56.63  ? 32  VAL J CG1   1 
ATOM   174  C CG2   . VAL A 1 26  ? 221.311 184.192 233.978 1.00 56.63  ? 32  VAL J CG2   1 
ATOM   175  N N     . PHE A 1 27  ? 220.613 187.690 237.178 1.00 56.79  ? 33  PHE J N     1 
ATOM   176  C CA    . PHE A 1 27  ? 220.150 188.256 238.436 1.00 56.79  ? 33  PHE J CA    1 
ATOM   177  C C     . PHE A 1 27  ? 219.061 189.276 238.154 1.00 56.79  ? 33  PHE J C     1 
ATOM   178  O O     . PHE A 1 27  ? 219.034 189.862 237.067 1.00 56.79  ? 33  PHE J O     1 
ATOM   179  C CB    . PHE A 1 27  ? 221.304 188.903 239.215 1.00 56.79  ? 33  PHE J CB    1 
ATOM   180  C CG    . PHE A 1 27  ? 221.985 190.020 238.485 1.00 56.79  ? 33  PHE J CG    1 
ATOM   181  C CD1   . PHE A 1 27  ? 223.063 189.772 237.664 1.00 56.79  ? 33  PHE J CD1   1 
ATOM   182  C CD2   . PHE A 1 27  ? 221.557 191.322 238.637 1.00 56.79  ? 33  PHE J CD2   1 
ATOM   183  C CE1   . PHE A 1 27  ? 223.688 190.800 237.000 1.00 56.79  ? 33  PHE J CE1   1 
ATOM   184  C CE2   . PHE A 1 27  ? 222.181 192.349 237.977 1.00 56.79  ? 33  PHE J CE2   1 
ATOM   185  C CZ    . PHE A 1 27  ? 223.245 192.087 237.159 1.00 56.79  ? 33  PHE J CZ    1 
ATOM   186  N N     . PRO A 1 28  ? 218.152 189.509 239.102 1.00 58.22  ? 34  PRO J N     1 
ATOM   187  C CA    . PRO A 1 28  ? 217.064 190.469 238.866 1.00 58.22  ? 34  PRO J CA    1 
ATOM   188  C C     . PRO A 1 28  ? 217.588 191.891 238.738 1.00 58.22  ? 34  PRO J C     1 
ATOM   189  O O     . PRO A 1 28  ? 218.384 192.351 239.558 1.00 58.22  ? 34  PRO J O     1 
ATOM   190  C CB    . PRO A 1 28  ? 216.176 190.311 240.105 1.00 58.22  ? 34  PRO J CB    1 
ATOM   191  C CG    . PRO A 1 28  ? 216.530 188.985 240.665 1.00 58.22  ? 34  PRO J CG    1 
ATOM   192  C CD    . PRO A 1 28  ? 217.979 188.792 240.373 1.00 58.22  ? 34  PRO J CD    1 
ATOM   193  N N     . SER A 1 29  ? 217.125 192.590 237.705 1.00 58.28  ? 35  SER J N     1 
ATOM   194  C CA    . SER A 1 29  ? 217.526 193.970 237.446 1.00 58.28  ? 35  SER J CA    1 
ATOM   195  C C     . SER A 1 29  ? 216.783 194.880 238.413 1.00 58.28  ? 35  SER J C     1 
ATOM   196  O O     . SER A 1 29  ? 215.745 195.454 238.087 1.00 58.28  ? 35  SER J O     1 
ATOM   197  C CB    . SER A 1 29  ? 217.239 194.348 236.000 1.00 58.28  ? 35  SER J CB    1 
ATOM   198  O OG    . SER A 1 29  ? 217.416 195.735 235.795 1.00 58.28  ? 35  SER J OG    1 
ATOM   199  N N     . ILE A 1 30  ? 217.332 195.024 239.619 1.00 58.67  ? 36  ILE J N     1 
ATOM   200  C CA    . ILE A 1 30  ? 216.674 195.754 240.696 1.00 58.67  ? 36  ILE J CA    1 
ATOM   201  C C     . ILE A 1 30  ? 217.726 196.530 241.473 1.00 58.67  ? 36  ILE J C     1 
ATOM   202  O O     . ILE A 1 30  ? 218.844 196.056 241.682 1.00 58.67  ? 36  ILE J O     1 
ATOM   203  C CB    . ILE A 1 30  ? 215.898 194.798 241.633 1.00 58.67  ? 36  ILE J CB    1 
ATOM   204  C CG1   . ILE A 1 30  ? 214.733 194.138 240.904 1.00 58.67  ? 36  ILE J CG1   1 
ATOM   205  C CG2   . ILE A 1 30  ? 215.383 195.525 242.845 1.00 58.67  ? 36  ILE J CG2   1 
ATOM   206  C CD1   . ILE A 1 30  ? 214.092 193.024 241.691 1.00 58.67  ? 36  ILE J CD1   1 
ATOM   207  N N     . VAL A 1 31  ? 217.359 197.733 241.903 1.00 59.15  ? 37  VAL J N     1 
ATOM   208  C CA    . VAL A 1 31  ? 218.183 198.551 242.783 1.00 59.15  ? 37  VAL J CA    1 
ATOM   209  C C     . VAL A 1 31  ? 217.329 198.931 243.982 1.00 59.15  ? 37  VAL J C     1 
ATOM   210  O O     . VAL A 1 31  ? 216.340 199.657 243.835 1.00 59.15  ? 37  VAL J O     1 
ATOM   211  C CB    . VAL A 1 31  ? 218.712 199.809 242.077 1.00 59.15  ? 37  VAL J CB    1 
ATOM   212  C CG1   . VAL A 1 31  ? 219.432 200.704 243.065 1.00 59.15  ? 37  VAL J CG1   1 
ATOM   213  C CG2   . VAL A 1 31  ? 219.625 199.428 240.937 1.00 59.15  ? 37  VAL J CG2   1 
ATOM   214  N N     . GLY A 1 32  ? 217.704 198.445 245.160 1.00 61.72  ? 38  GLY J N     1 
ATOM   215  C CA    . GLY A 1 32  ? 216.938 198.663 246.373 1.00 61.72  ? 38  GLY J CA    1 
ATOM   216  C C     . GLY A 1 32  ? 217.677 199.562 247.344 1.00 61.72  ? 38  GLY J C     1 
ATOM   217  O O     . GLY A 1 32  ? 218.908 199.564 247.392 1.00 61.72  ? 38  GLY J O     1 
ATOM   218  N N     . ARG A 1 33  ? 216.916 200.329 248.119 1.00 65.35  ? 39  ARG J N     1 
ATOM   219  C CA    . ARG A 1 33  ? 217.460 201.224 249.125 1.00 65.35  ? 39  ARG J CA    1 
ATOM   220  C C     . ARG A 1 33  ? 216.729 201.026 250.444 1.00 65.35  ? 39  ARG J C     1 
ATOM   221  O O     . ARG A 1 33  ? 215.514 200.798 250.454 1.00 65.35  ? 39  ARG J O     1 
ATOM   222  C CB    . ARG A 1 33  ? 217.344 202.685 248.683 1.00 65.35  ? 39  ARG J CB    1 
ATOM   223  C CG    . ARG A 1 33  ? 218.198 203.027 247.488 1.00 65.35  ? 39  ARG J CG    1 
ATOM   224  C CD    . ARG A 1 33  ? 218.107 204.499 247.146 1.00 65.35  ? 39  ARG J CD    1 
ATOM   225  N NE    . ARG A 1 33  ? 219.032 204.859 246.078 1.00 65.35  ? 39  ARG J NE    1 
ATOM   226  C CZ    . ARG A 1 33  ? 218.805 204.636 244.789 1.00 65.35  ? 39  ARG J CZ    1 
ATOM   227  N NH1   . ARG A 1 33  ? 217.677 204.054 244.402 1.00 65.35  ? 39  ARG J NH1   1 
ATOM   228  N NH2   . ARG A 1 33  ? 219.705 204.996 243.884 1.00 65.35  ? 39  ARG J NH2   1 
ATOM   229  N N     . PRO A 1 34  ? 217.435 201.109 251.570 1.00 64.02  ? 40  PRO J N     1 
ATOM   230  C CA    . PRO A 1 34  ? 216.789 200.868 252.866 1.00 64.02  ? 40  PRO J CA    1 
ATOM   231  C C     . PRO A 1 34  ? 215.788 201.963 253.202 1.00 64.02  ? 40  PRO J C     1 
ATOM   232  O O     . PRO A 1 34  ? 216.092 203.153 253.110 1.00 64.02  ? 40  PRO J O     1 
ATOM   233  C CB    . PRO A 1 34  ? 217.964 200.859 253.847 1.00 64.02  ? 40  PRO J CB    1 
ATOM   234  C CG    . PRO A 1 34  ? 219.000 201.691 253.177 1.00 64.02  ? 40  PRO J CG    1 
ATOM   235  C CD    . PRO A 1 34  ? 218.870 201.395 251.719 1.00 64.02  ? 40  PRO J CD    1 
ATOM   236  N N     . ARG A 1 35  ? 214.586 201.549 253.597 1.00 67.01  ? 41  ARG J N     1 
ATOM   237  C CA    . ARG A 1 35  ? 213.542 202.485 253.992 1.00 67.01  ? 41  ARG J CA    1 
ATOM   238  C C     . ARG A 1 35  ? 213.653 202.895 255.453 1.00 67.01  ? 41  ARG J C     1 
ATOM   239  O O     . ARG A 1 35  ? 213.306 204.026 255.807 1.00 67.01  ? 41  ARG J O     1 
ATOM   240  C CB    . ARG A 1 35  ? 212.160 201.872 253.763 1.00 67.01  ? 41  ARG J CB    1 
ATOM   241  C CG    . ARG A 1 35  ? 212.032 201.009 252.533 1.00 67.01  ? 41  ARG J CG    1 
ATOM   242  C CD    . ARG A 1 35  ? 210.865 200.057 252.692 1.00 67.01  ? 41  ARG J CD    1 
ATOM   243  N NE    . ARG A 1 35  ? 209.739 200.706 253.352 1.00 67.01  ? 41  ARG J NE    1 
ATOM   244  C CZ    . ARG A 1 35  ? 208.735 200.054 253.924 1.00 67.01  ? 41  ARG J CZ    1 
ATOM   245  N NH1   . ARG A 1 35  ? 208.713 198.730 253.922 1.00 67.01  ? 41  ARG J NH1   1 
ATOM   246  N NH2   . ARG A 1 35  ? 207.753 200.728 254.503 1.00 67.01  ? 41  ARG J NH2   1 
ATOM   247  N N     . HIS A 1 36  ? 214.129 201.994 256.307 1.00 70.26  ? 42  HIS J N     1 
ATOM   248  C CA    . HIS A 1 36  ? 213.965 202.130 257.747 1.00 70.26  ? 42  HIS J CA    1 
ATOM   249  C C     . HIS A 1 36  ? 215.113 202.933 258.354 1.00 70.26  ? 42  HIS J C     1 
ATOM   250  O O     . HIS A 1 36  ? 215.910 203.563 257.655 1.00 70.26  ? 42  HIS J O     1 
ATOM   251  C CB    . HIS A 1 36  ? 213.822 200.752 258.380 1.00 70.26  ? 42  HIS J CB    1 
ATOM   252  C CG    . HIS A 1 36  ? 212.536 200.073 258.039 1.00 70.26  ? 42  HIS J CG    1 
ATOM   253  N ND1   . HIS A 1 36  ? 211.317 200.708 258.129 1.00 70.26  ? 42  HIS J ND1   1 
ATOM   254  C CD2   . HIS A 1 36  ? 212.276 198.820 257.601 1.00 70.26  ? 42  HIS J CD2   1 
ATOM   255  C CE1   . HIS A 1 36  ? 210.361 199.873 257.765 1.00 70.26  ? 42  HIS J CE1   1 
ATOM   256  N NE2   . HIS A 1 36  ? 210.916 198.721 257.439 1.00 70.26  ? 42  HIS J NE2   1 
ATOM   257  N N     . GLN A 1 37  ? 215.198 202.915 259.684 1.00 77.11  ? 43  GLN J N     1 
ATOM   258  C CA    . GLN A 1 37  ? 216.017 203.883 260.404 1.00 77.11  ? 43  GLN J CA    1 
ATOM   259  C C     . GLN A 1 37  ? 217.493 203.497 260.408 1.00 77.11  ? 43  GLN J C     1 
ATOM   260  O O     . GLN A 1 37  ? 218.329 204.198 259.830 1.00 77.11  ? 43  GLN J O     1 
ATOM   261  C CB    . GLN A 1 37  ? 215.496 204.021 261.837 1.00 77.11  ? 43  GLN J CB    1 
ATOM   262  C CG    . GLN A 1 37  ? 215.953 205.269 262.561 1.00 77.11  ? 43  GLN J CG    1 
ATOM   263  C CD    . GLN A 1 37  ? 215.042 205.629 263.719 1.00 77.11  ? 43  GLN J CD    1 
ATOM   264  O OE1   . GLN A 1 37  ? 213.900 205.175 263.788 1.00 77.11  ? 43  GLN J OE1   1 
ATOM   265  N NE2   . GLN A 1 37  ? 215.544 206.445 264.636 1.00 77.11  ? 43  GLN J NE2   1 
ATOM   266  N N     . GLY A 1 38  ? 217.830 202.386 261.052 1.00 79.55  ? 44  GLY J N     1 
ATOM   267  C CA    . GLY A 1 38  ? 219.222 202.013 261.209 1.00 79.55  ? 44  GLY J CA    1 
ATOM   268  C C     . GLY A 1 38  ? 219.760 202.501 262.537 1.00 79.55  ? 44  GLY J C     1 
ATOM   269  O O     . GLY A 1 38  ? 220.009 203.699 262.700 1.00 79.55  ? 44  GLY J O     1 
ATOM   270  N N     . VAL A 1 39  ? 219.945 201.596 263.495 1.00 80.67  ? 45  VAL J N     1 
ATOM   271  C CA    . VAL A 1 39  ? 220.272 202.007 264.855 1.00 80.67  ? 45  VAL J CA    1 
ATOM   272  C C     . VAL A 1 39  ? 221.562 201.358 265.335 1.00 80.67  ? 45  VAL J C     1 
ATOM   273  O O     . VAL A 1 39  ? 222.244 201.895 266.214 1.00 80.67  ? 45  VAL J O     1 
ATOM   274  C CB    . VAL A 1 39  ? 219.112 201.685 265.811 1.00 80.67  ? 45  VAL J CB    1 
ATOM   275  C CG1   . VAL A 1 39  ? 217.954 202.624 265.559 1.00 80.67  ? 45  VAL J CG1   1 
ATOM   276  C CG2   . VAL A 1 39  ? 218.669 200.250 265.629 1.00 80.67  ? 45  VAL J CG2   1 
ATOM   277  N N     . MET A 1 40  ? 221.911 200.208 264.770 1.00 84.40  ? 46  MET J N     1 
ATOM   278  C CA    . MET A 1 40  ? 223.110 199.495 265.194 1.00 84.40  ? 46  MET J CA    1 
ATOM   279  C C     . MET A 1 40  ? 224.332 200.180 264.596 1.00 84.40  ? 46  MET J C     1 
ATOM   280  O O     . MET A 1 40  ? 224.585 200.074 263.394 1.00 84.40  ? 46  MET J O     1 
ATOM   281  C CB    . MET A 1 40  ? 223.037 198.028 264.781 1.00 84.40  ? 46  MET J CB    1 
ATOM   282  C CG    . MET A 1 40  ? 222.540 197.112 265.887 1.00 84.40  ? 46  MET J CG    1 
ATOM   283  S SD    . MET A 1 40  ? 222.546 195.371 265.432 1.00 84.40  ? 46  MET J SD    1 
ATOM   284  C CE    . MET A 1 40  ? 224.179 195.219 264.718 1.00 84.40  ? 46  MET J CE    1 
ATOM   285  N N     . VAL A 1 41  ? 225.091 200.886 265.435 1.00 85.66  ? 47  VAL J N     1 
ATOM   286  C CA    . VAL A 1 41  ? 226.288 201.574 264.970 1.00 85.66  ? 47  VAL J CA    1 
ATOM   287  C C     . VAL A 1 41  ? 227.373 200.556 264.654 1.00 85.66  ? 47  VAL J C     1 
ATOM   288  O O     . VAL A 1 41  ? 227.542 199.557 265.365 1.00 85.66  ? 47  VAL J O     1 
ATOM   289  C CB    . VAL A 1 41  ? 226.756 202.590 266.025 1.00 85.66  ? 47  VAL J CB    1 
ATOM   290  C CG1   . VAL A 1 41  ? 228.208 202.983 265.802 1.00 85.66  ? 47  VAL J CG1   1 
ATOM   291  C CG2   . VAL A 1 41  ? 225.862 203.814 266.005 1.00 85.66  ? 47  VAL J CG2   1 
ATOM   292  N N     . GLY A 1 42  ? 228.115 200.801 263.578 1.00 88.56  ? 48  GLY J N     1 
ATOM   293  C CA    . GLY A 1 42  ? 229.176 199.909 263.166 1.00 88.56  ? 48  GLY J CA    1 
ATOM   294  C C     . GLY A 1 42  ? 228.743 198.758 262.292 1.00 88.56  ? 48  GLY J C     1 
ATOM   295  O O     . GLY A 1 42  ? 229.571 197.893 261.983 1.00 88.56  ? 48  GLY J O     1 
ATOM   296  N N     . MET A 1 43  ? 227.474 198.717 261.882 1.00 90.57  ? 49  MET J N     1 
ATOM   297  C CA    . MET A 1 43  ? 226.980 197.603 261.082 1.00 90.57  ? 49  MET J CA    1 
ATOM   298  C C     . MET A 1 43  ? 227.654 197.539 259.719 1.00 90.57  ? 49  MET J C     1 
ATOM   299  O O     . MET A 1 43  ? 227.788 196.452 259.147 1.00 90.57  ? 49  MET J O     1 
ATOM   300  C CB    . MET A 1 43  ? 225.468 197.717 260.906 1.00 90.57  ? 49  MET J CB    1 
ATOM   301  C CG    . MET A 1 43  ? 225.016 199.102 260.479 1.00 90.57  ? 49  MET J CG    1 
ATOM   302  S SD    . MET A 1 43  ? 223.260 199.204 260.098 1.00 90.57  ? 49  MET J SD    1 
ATOM   303  C CE    . MET A 1 43  ? 223.231 198.475 258.463 1.00 90.57  ? 49  MET J CE    1 
ATOM   304  N N     . GLY A 1 44  ? 228.090 198.677 259.191 1.00 89.42  ? 50  GLY J N     1 
ATOM   305  C CA    . GLY A 1 44  ? 228.579 198.724 257.828 1.00 89.42  ? 50  GLY J CA    1 
ATOM   306  C C     . GLY A 1 44  ? 227.444 198.834 256.833 1.00 89.42  ? 50  GLY J C     1 
ATOM   307  O O     . GLY A 1 44  ? 227.271 197.973 255.966 1.00 89.42  ? 50  GLY J O     1 
ATOM   308  N N     . GLN A 1 45  ? 226.660 199.900 256.960 1.00 86.95  ? 51  GLN J N     1 
ATOM   309  C CA    . GLN A 1 45  ? 225.521 200.130 256.085 1.00 86.95  ? 51  GLN J CA    1 
ATOM   310  C C     . GLN A 1 45  ? 225.990 200.470 254.677 1.00 86.95  ? 51  GLN J C     1 
ATOM   311  O O     . GLN A 1 45  ? 226.931 201.249 254.497 1.00 86.95  ? 51  GLN J O     1 
ATOM   312  C CB    . GLN A 1 45  ? 224.659 201.264 256.637 1.00 86.95  ? 51  GLN J CB    1 
ATOM   313  C CG    . GLN A 1 45  ? 225.461 202.489 257.045 1.00 86.95  ? 51  GLN J CG    1 
ATOM   314  C CD    . GLN A 1 45  ? 224.587 203.669 257.409 1.00 86.95  ? 51  GLN J CD    1 
ATOM   315  O OE1   . GLN A 1 45  ? 223.710 204.066 256.643 1.00 86.95  ? 51  GLN J OE1   1 
ATOM   316  N NE2   . GLN A 1 45  ? 224.825 204.241 258.583 1.00 86.95  ? 51  GLN J NE2   1 
ATOM   317  N N     . LYS A 1 46  ? 225.339 199.881 253.682 1.00 77.32  ? 52  LYS J N     1 
ATOM   318  C CA    . LYS A 1 46  ? 225.603 200.224 252.295 1.00 77.32  ? 52  LYS J CA    1 
ATOM   319  C C     . LYS A 1 46  ? 224.551 201.201 251.782 1.00 77.32  ? 52  LYS J C     1 
ATOM   320  O O     . LYS A 1 46  ? 223.444 201.299 252.312 1.00 77.32  ? 52  LYS J O     1 
ATOM   321  C CB    . LYS A 1 46  ? 225.636 198.972 251.422 1.00 77.32  ? 52  LYS J CB    1 
ATOM   322  C CG    . LYS A 1 46  ? 227.033 198.589 250.978 1.00 77.32  ? 52  LYS J CG    1 
ATOM   323  C CD    . LYS A 1 46  ? 227.132 197.112 250.644 1.00 77.32  ? 52  LYS J CD    1 
ATOM   324  C CE    . LYS A 1 46  ? 226.405 196.779 249.354 1.00 77.32  ? 52  LYS J CE    1 
ATOM   325  N NZ    . LYS A 1 46  ? 226.619 195.360 248.963 1.00 77.32  ? 52  LYS J NZ    1 
ATOM   326  N N     . ASP A 1 47  ? 224.917 201.929 250.728 1.00 77.77  ? 53  ASP J N     1 
ATOM   327  C CA    . ASP A 1 47  ? 224.029 202.958 250.201 1.00 77.77  ? 53  ASP J CA    1 
ATOM   328  C C     . ASP A 1 47  ? 222.828 202.345 249.494 1.00 77.77  ? 53  ASP J C     1 
ATOM   329  O O     . ASP A 1 47  ? 221.693 202.797 249.684 1.00 77.77  ? 53  ASP J O     1 
ATOM   330  C CB    . ASP A 1 47  ? 224.800 203.874 249.253 1.00 77.77  ? 53  ASP J CB    1 
ATOM   331  C CG    . ASP A 1 47  ? 224.322 205.306 249.310 1.00 77.77  ? 53  ASP J CG    1 
ATOM   332  O OD1   . ASP A 1 47  ? 223.364 205.585 250.062 1.00 77.77  ? 53  ASP J OD1   1 
ATOM   333  O OD2   . ASP A 1 47  ? 224.905 206.155 248.605 1.00 77.77  ? 53  ASP J OD2   1 
ATOM   334  N N     . SER A 1 48  ? 223.057 201.318 248.681 1.00 68.98  ? 54  SER J N     1 
ATOM   335  C CA    . SER A 1 48  ? 221.990 200.657 247.945 1.00 68.98  ? 54  SER J CA    1 
ATOM   336  C C     . SER A 1 48  ? 222.515 199.334 247.415 1.00 68.98  ? 54  SER J C     1 
ATOM   337  O O     . SER A 1 48  ? 223.669 199.245 246.995 1.00 68.98  ? 54  SER J O     1 
ATOM   338  C CB    . SER A 1 48  ? 221.485 201.527 246.791 1.00 68.98  ? 54  SER J CB    1 
ATOM   339  O OG    . SER A 1 48  ? 222.491 201.699 245.812 1.00 68.98  ? 54  SER J OG    1 
ATOM   340  N N     . TYR A 1 49  ? 221.665 198.316 247.436 1.00 66.78  ? 55  TYR J N     1 
ATOM   341  C CA    . TYR A 1 49  ? 222.025 196.981 246.986 1.00 66.78  ? 55  TYR J CA    1 
ATOM   342  C C     . TYR A 1 49  ? 221.409 196.713 245.623 1.00 66.78  ? 55  TYR J C     1 
ATOM   343  O O     . TYR A 1 49  ? 220.249 197.055 245.377 1.00 66.78  ? 55  TYR J O     1 
ATOM   344  C CB    . TYR A 1 49  ? 221.563 195.918 247.984 1.00 66.78  ? 55  TYR J CB    1 
ATOM   345  C CG    . TYR A 1 49  ? 221.865 196.258 249.422 1.00 66.78  ? 55  TYR J CG    1 
ATOM   346  C CD1   . TYR A 1 49  ? 220.973 196.991 250.184 1.00 66.78  ? 55  TYR J CD1   1 
ATOM   347  C CD2   . TYR A 1 49  ? 223.044 195.845 250.017 1.00 66.78  ? 55  TYR J CD2   1 
ATOM   348  C CE1   . TYR A 1 49  ? 221.246 197.304 251.494 1.00 66.78  ? 55  TYR J CE1   1 
ATOM   349  C CE2   . TYR A 1 49  ? 223.326 196.154 251.328 1.00 66.78  ? 55  TYR J CE2   1 
ATOM   350  C CZ    . TYR A 1 49  ? 222.423 196.884 252.062 1.00 66.78  ? 55  TYR J CZ    1 
ATOM   351  O OH    . TYR A 1 49  ? 222.698 197.194 253.372 1.00 66.78  ? 55  TYR J OH    1 
ATOM   352  N N     . VAL A 1 50  ? 222.189 196.096 244.741 1.00 62.13  ? 56  VAL J N     1 
ATOM   353  C CA    . VAL A 1 50  ? 221.756 195.795 243.387 1.00 62.13  ? 56  VAL J CA    1 
ATOM   354  C C     . VAL A 1 50  ? 221.699 194.286 243.210 1.00 62.13  ? 56  VAL J C     1 
ATOM   355  O O     . VAL A 1 50  ? 222.267 193.520 243.989 1.00 62.13  ? 56  VAL J O     1 
ATOM   356  C CB    . VAL A 1 50  ? 222.684 196.423 242.335 1.00 62.13  ? 56  VAL J CB    1 
ATOM   357  C CG1   . VAL A 1 50  ? 222.670 197.927 242.454 1.00 62.13  ? 56  VAL J CG1   1 
ATOM   358  C CG2   . VAL A 1 50  ? 224.079 195.904 242.520 1.00 62.13  ? 56  VAL J CG2   1 
ATOM   359  N N     . GLY A 1 51  ? 220.996 193.864 242.164 1.00 61.91  ? 57  GLY J N     1 
ATOM   360  C CA    . GLY A 1 51  ? 220.968 192.457 241.836 1.00 61.91  ? 57  GLY J CA    1 
ATOM   361  C C     . GLY A 1 51  ? 220.191 191.642 242.852 1.00 61.91  ? 57  GLY J C     1 
ATOM   362  O O     . GLY A 1 51  ? 219.246 192.118 243.485 1.00 61.91  ? 57  GLY J O     1 
ATOM   363  N N     . ASP A 1 52  ? 220.600 190.386 243.008 1.00 68.29  ? 58  ASP J N     1 
ATOM   364  C CA    . ASP A 1 52  ? 219.940 189.490 243.946 1.00 68.29  ? 58  ASP J CA    1 
ATOM   365  C C     . ASP A 1 52  ? 220.467 189.623 245.366 1.00 68.29  ? 58  ASP J C     1 
ATOM   366  O O     . ASP A 1 52  ? 220.043 188.859 246.240 1.00 68.29  ? 58  ASP J O     1 
ATOM   367  C CB    . ASP A 1 52  ? 220.063 188.043 243.468 1.00 68.29  ? 58  ASP J CB    1 
ATOM   368  C CG    . ASP A 1 52  ? 221.494 187.616 243.271 1.00 68.29  ? 58  ASP J CG    1 
ATOM   369  O OD1   . ASP A 1 52  ? 222.397 188.462 243.425 1.00 68.29  ? 58  ASP J OD1   1 
ATOM   370  O OD2   . ASP A 1 52  ? 221.713 186.428 242.958 1.00 68.29  ? 58  ASP J OD2   1 
ATOM   371  N N     . GLU A 1 53  ? 221.378 190.563 245.620 1.00 70.18  ? 59  GLU J N     1 
ATOM   372  C CA    . GLU A 1 53  ? 221.668 190.933 246.998 1.00 70.18  ? 59  GLU J CA    1 
ATOM   373  C C     . GLU A 1 53  ? 220.539 191.765 247.585 1.00 70.18  ? 59  GLU J C     1 
ATOM   374  O O     . GLU A 1 53  ? 220.268 191.682 248.787 1.00 70.18  ? 59  GLU J O     1 
ATOM   375  C CB    . GLU A 1 53  ? 222.985 191.695 247.081 1.00 70.18  ? 59  GLU J CB    1 
ATOM   376  C CG    . GLU A 1 53  ? 223.441 191.956 248.499 1.00 70.18  ? 59  GLU J CG    1 
ATOM   377  C CD    . GLU A 1 53  ? 224.522 193.008 248.571 1.00 70.18  ? 59  GLU J CD    1 
ATOM   378  O OE1   . GLU A 1 53  ? 224.885 193.557 247.509 1.00 70.18  ? 59  GLU J OE1   1 
ATOM   379  O OE2   . GLU A 1 53  ? 225.010 193.287 249.686 1.00 70.18  ? 59  GLU J OE2   1 
ATOM   380  N N     . ALA A 1 54  ? 219.872 192.569 246.756 1.00 63.94  ? 60  ALA J N     1 
ATOM   381  C CA    . ALA A 1 54  ? 218.657 193.249 247.177 1.00 63.94  ? 60  ALA J CA    1 
ATOM   382  C C     . ALA A 1 54  ? 217.461 192.314 247.225 1.00 63.94  ? 60  ALA J C     1 
ATOM   383  O O     . ALA A 1 54  ? 216.427 192.685 247.786 1.00 63.94  ? 60  ALA J O     1 
ATOM   384  C CB    . ALA A 1 54  ? 218.357 194.420 246.244 1.00 63.94  ? 60  ALA J CB    1 
ATOM   385  N N     . GLN A 1 55  ? 217.576 191.120 246.650 1.00 64.50  ? 61  GLN J N     1 
ATOM   386  C CA    . GLN A 1 55  ? 216.521 190.123 246.750 1.00 64.50  ? 61  GLN J CA    1 
ATOM   387  C C     . GLN A 1 55  ? 216.574 189.356 248.064 1.00 64.50  ? 61  GLN J C     1 
ATOM   388  O O     . GLN A 1 55  ? 215.540 188.860 248.520 1.00 64.50  ? 61  GLN J O     1 
ATOM   389  C CB    . GLN A 1 55  ? 216.618 189.151 245.574 1.00 64.50  ? 61  GLN J CB    1 
ATOM   390  C CG    . GLN A 1 55  ? 215.458 188.182 245.448 1.00 64.50  ? 61  GLN J CG    1 
ATOM   391  C CD    . GLN A 1 55  ? 214.341 188.728 244.592 1.00 64.50  ? 61  GLN J CD    1 
ATOM   392  O OE1   . GLN A 1 55  ? 214.365 189.889 244.189 1.00 64.50  ? 61  GLN J OE1   1 
ATOM   393  N NE2   . GLN A 1 55  ? 213.354 187.893 244.306 1.00 64.50  ? 61  GLN J NE2   1 
ATOM   394  N N     . SER A 1 56  ? 217.748 189.259 248.686 1.00 66.53  ? 62  SER J N     1 
ATOM   395  C CA    . SER A 1 56  ? 217.892 188.551 249.951 1.00 66.53  ? 62  SER J CA    1 
ATOM   396  C C     . SER A 1 56  ? 217.608 189.437 251.154 1.00 66.53  ? 62  SER J C     1 
ATOM   397  O O     . SER A 1 56  ? 217.146 188.938 252.185 1.00 66.53  ? 62  SER J O     1 
ATOM   398  C CB    . SER A 1 56  ? 219.300 187.968 250.071 1.00 66.53  ? 62  SER J CB    1 
ATOM   399  O OG    . SER A 1 56  ? 220.192 188.916 250.628 1.00 66.53  ? 62  SER J OG    1 
ATOM   400  N N     . LYS A 1 57  ? 217.881 190.738 251.046 1.00 64.19  ? 63  LYS J N     1 
ATOM   401  C CA    . LYS A 1 57  ? 217.477 191.722 252.042 1.00 64.19  ? 63  LYS J CA    1 
ATOM   402  C C     . LYS A 1 57  ? 216.161 192.386 251.680 1.00 64.19  ? 63  LYS J C     1 
ATOM   403  O O     . LYS A 1 57  ? 215.952 193.566 251.984 1.00 64.19  ? 63  LYS J O     1 
ATOM   404  C CB    . LYS A 1 57  ? 218.575 192.767 252.225 1.00 64.19  ? 63  LYS J CB    1 
ATOM   405  C CG    . LYS A 1 57  ? 219.862 192.188 252.765 1.00 64.19  ? 63  LYS J CG    1 
ATOM   406  C CD    . LYS A 1 57  ? 220.948 193.237 252.861 1.00 64.19  ? 63  LYS J CD    1 
ATOM   407  C CE    . LYS A 1 57  ? 222.273 192.600 253.227 1.00 64.19  ? 63  LYS J CE    1 
ATOM   408  N NZ    . LYS A 1 57  ? 222.566 191.429 252.359 1.00 64.19  ? 63  LYS J NZ    1 
ATOM   409  N N     . ARG A 1 58  ? 215.274 191.641 251.023 1.00 60.63  ? 64  ARG J N     1 
ATOM   410  C CA    . ARG A 1 58  ? 214.055 192.197 250.451 1.00 60.63  ? 64  ARG J CA    1 
ATOM   411  C C     . ARG A 1 58  ? 213.159 192.832 251.503 1.00 60.63  ? 64  ARG J C     1 
ATOM   412  O O     . ARG A 1 58  ? 212.350 193.705 251.178 1.00 60.63  ? 64  ARG J O     1 
ATOM   413  C CB    . ARG A 1 58  ? 213.310 191.083 249.724 1.00 60.63  ? 64  ARG J CB    1 
ATOM   414  C CG    . ARG A 1 58  ? 212.308 191.520 248.702 1.00 60.63  ? 64  ARG J CG    1 
ATOM   415  C CD    . ARG A 1 58  ? 211.763 190.293 248.009 1.00 60.63  ? 64  ARG J CD    1 
ATOM   416  N NE    . ARG A 1 58  ? 211.710 189.164 248.929 1.00 60.63  ? 64  ARG J NE    1 
ATOM   417  C CZ    . ARG A 1 58  ? 211.656 187.893 248.551 1.00 60.63  ? 64  ARG J CZ    1 
ATOM   418  N NH1   . ARG A 1 58  ? 211.650 187.583 247.265 1.00 60.63  ? 64  ARG J NH1   1 
ATOM   419  N NH2   . ARG A 1 58  ? 211.614 186.932 249.461 1.00 60.63  ? 64  ARG J NH2   1 
ATOM   420  N N     . GLY A 1 59  ? 213.286 192.416 252.763 1.00 57.86  ? 65  GLY J N     1 
ATOM   421  C CA    . GLY A 1 59  ? 212.340 192.852 253.775 1.00 57.86  ? 65  GLY J CA    1 
ATOM   422  C C     . GLY A 1 59  ? 212.447 194.320 254.136 1.00 57.86  ? 65  GLY J C     1 
ATOM   423  O O     . GLY A 1 59  ? 211.432 194.972 254.390 1.00 57.86  ? 65  GLY J O     1 
ATOM   424  N N     . ILE A 1 60  ? 213.663 194.862 254.164 1.00 59.50  ? 66  ILE J N     1 
ATOM   425  C CA    . ILE A 1 60  ? 213.902 196.225 254.621 1.00 59.50  ? 66  ILE J CA    1 
ATOM   426  C C     . ILE A 1 60  ? 214.204 197.179 253.485 1.00 59.50  ? 66  ILE J C     1 
ATOM   427  O O     . ILE A 1 60  ? 214.431 198.369 253.739 1.00 59.50  ? 66  ILE J O     1 
ATOM   428  C CB    . ILE A 1 60  ? 215.034 196.270 255.661 1.00 59.50  ? 66  ILE J CB    1 
ATOM   429  C CG1   . ILE A 1 60  ? 216.310 195.681 255.061 1.00 59.50  ? 66  ILE J CG1   1 
ATOM   430  C CG2   . ILE A 1 60  ? 214.631 195.524 256.912 1.00 59.50  ? 66  ILE J CG2   1 
ATOM   431  C CD1   . ILE A 1 60  ? 217.576 196.202 255.680 1.00 59.50  ? 66  ILE J CD1   1 
ATOM   432  N N     . LEU A 1 61  ? 214.224 196.707 252.246 1.00 60.53  ? 67  LEU J N     1 
ATOM   433  C CA    . LEU A 1 61  ? 214.521 197.548 251.099 1.00 60.53  ? 67  LEU J CA    1 
ATOM   434  C C     . LEU A 1 61  ? 213.249 197.880 250.331 1.00 60.53  ? 67  LEU J C     1 
ATOM   435  O O     . LEU A 1 61  ? 212.233 197.191 250.434 1.00 60.53  ? 67  LEU J O     1 
ATOM   436  C CB    . LEU A 1 61  ? 215.518 196.861 250.167 1.00 60.53  ? 67  LEU J CB    1 
ATOM   437  C CG    . LEU A 1 61  ? 216.849 196.432 250.770 1.00 60.53  ? 67  LEU J CG    1 
ATOM   438  C CD1   . LEU A 1 61  ? 217.637 195.655 249.751 1.00 60.53  ? 67  LEU J CD1   1 
ATOM   439  C CD2   . LEU A 1 61  ? 217.632 197.634 251.235 1.00 60.53  ? 67  LEU J CD2   1 
ATOM   440  N N     . THR A 1 62  ? 213.320 198.957 249.558 1.00 61.41  ? 68  THR J N     1 
ATOM   441  C CA    . THR A 1 62  ? 212.301 199.290 248.572 1.00 61.41  ? 68  THR J CA    1 
ATOM   442  C C     . THR A 1 62  ? 212.886 199.041 247.186 1.00 61.41  ? 68  THR J C     1 
ATOM   443  O O     . THR A 1 62  ? 213.844 199.705 246.777 1.00 61.41  ? 68  THR J O     1 
ATOM   444  C CB    . THR A 1 62  ? 211.808 200.730 248.744 1.00 61.41  ? 68  THR J CB    1 
ATOM   445  O OG1   . THR A 1 62  ? 210.831 201.034 247.740 1.00 61.41  ? 68  THR J OG1   1 
ATOM   446  C CG2   . THR A 1 62  ? 212.948 201.746 248.711 1.00 61.41  ? 68  THR J CG2   1 
ATOM   447  N N     . LEU A 1 63  ? 212.336 198.057 246.484 1.00 58.19  ? 69  LEU J N     1 
ATOM   448  C CA    . LEU A 1 63  ? 212.891 197.613 245.216 1.00 58.19  ? 69  LEU J CA    1 
ATOM   449  C C     . LEU A 1 63  ? 212.378 198.477 244.075 1.00 58.19  ? 69  LEU J C     1 
ATOM   450  O O     . LEU A 1 63  ? 211.195 198.817 244.021 1.00 58.19  ? 69  LEU J O     1 
ATOM   451  C CB    . LEU A 1 63  ? 212.536 196.151 244.963 1.00 58.19  ? 69  LEU J CB    1 
ATOM   452  C CG    . LEU A 1 63  ? 212.829 195.194 246.114 1.00 58.19  ? 69  LEU J CG    1 
ATOM   453  C CD1   . LEU A 1 63  ? 212.468 193.778 245.720 1.00 58.19  ? 69  LEU J CD1   1 
ATOM   454  C CD2   . LEU A 1 63  ? 214.282 195.285 246.514 1.00 58.19  ? 69  LEU J CD2   1 
ATOM   455  N N     . LYS A 1 64  ? 213.276 198.825 243.159 1.00 60.48  ? 70  LYS J N     1 
ATOM   456  C CA    . LYS A 1 64  ? 212.931 199.647 242.011 1.00 60.48  ? 70  LYS J CA    1 
ATOM   457  C C     . LYS A 1 64  ? 213.477 199.016 240.742 1.00 60.48  ? 70  LYS J C     1 
ATOM   458  O O     . LYS A 1 64  ? 214.542 198.395 240.755 1.00 60.48  ? 70  LYS J O     1 
ATOM   459  C CB    . LYS A 1 64  ? 213.474 201.067 242.159 1.00 60.48  ? 70  LYS J CB    1 
ATOM   460  C CG    . LYS A 1 64  ? 212.755 201.882 243.206 1.00 60.48  ? 70  LYS J CG    1 
ATOM   461  C CD    . LYS A 1 64  ? 212.888 203.365 242.938 1.00 60.48  ? 70  LYS J CD    1 
ATOM   462  C CE    . LYS A 1 64  ? 211.932 204.150 243.813 1.00 60.48  ? 70  LYS J CE    1 
ATOM   463  N NZ    . LYS A 1 64  ? 210.606 203.483 243.872 1.00 60.48  ? 70  LYS J NZ    1 
ATOM   464  N N     . TYR A 1 65  ? 212.734 199.174 239.650 1.00 59.50  ? 71  TYR J N     1 
ATOM   465  C CA    . TYR A 1 65  ? 213.164 198.695 238.351 1.00 59.50  ? 71  TYR J CA    1 
ATOM   466  C C     . TYR A 1 65  ? 213.543 199.880 237.483 1.00 59.50  ? 71  TYR J C     1 
ATOM   467  O O     . TYR A 1 65  ? 212.680 200.722 237.199 1.00 59.50  ? 71  TYR J O     1 
ATOM   468  C CB    . TYR A 1 65  ? 212.056 197.894 237.687 1.00 59.50  ? 71  TYR J CB    1 
ATOM   469  C CG    . TYR A 1 65  ? 211.876 196.510 238.252 1.00 59.50  ? 71  TYR J CG    1 
ATOM   470  C CD1   . TYR A 1 65  ? 211.003 196.277 239.301 1.00 59.50  ? 71  TYR J CD1   1 
ATOM   471  C CD2   . TYR A 1 65  ? 212.572 195.434 237.730 1.00 59.50  ? 71  TYR J CD2   1 
ATOM   472  C CE1   . TYR A 1 65  ? 210.833 195.014 239.818 1.00 59.50  ? 71  TYR J CE1   1 
ATOM   473  C CE2   . TYR A 1 65  ? 212.408 194.169 238.239 1.00 59.50  ? 71  TYR J CE2   1 
ATOM   474  C CZ    . TYR A 1 65  ? 211.538 193.965 239.283 1.00 59.50  ? 71  TYR J CZ    1 
ATOM   475  O OH    . TYR A 1 65  ? 211.373 192.701 239.795 1.00 59.50  ? 71  TYR J OH    1 
ATOM   476  N N     . PRO A 1 66  ? 214.796 199.998 237.039 1.00 58.56  ? 72  PRO J N     1 
ATOM   477  C CA    . PRO A 1 66  ? 215.174 201.120 236.174 1.00 58.56  ? 72  PRO J CA    1 
ATOM   478  C C     . PRO A 1 66  ? 214.743 200.961 234.727 1.00 58.56  ? 72  PRO J C     1 
ATOM   479  O O     . PRO A 1 66  ? 214.965 201.880 233.932 1.00 58.56  ? 72  PRO J O     1 
ATOM   480  C CB    . PRO A 1 66  ? 216.699 201.132 236.293 1.00 58.56  ? 72  PRO J CB    1 
ATOM   481  C CG    . PRO A 1 66  ? 217.047 199.731 236.536 1.00 58.56  ? 72  PRO J CG    1 
ATOM   482  C CD    . PRO A 1 66  ? 215.948 199.147 237.369 1.00 58.56  ? 72  PRO J CD    1 
ATOM   483  N N     . ILE A 1 67  ? 214.144 199.832 234.362 1.00 59.33  ? 73  ILE J N     1 
ATOM   484  C CA    . ILE A 1 67  ? 213.593 199.613 233.031 1.00 59.33  ? 73  ILE J CA    1 
ATOM   485  C C     . ILE A 1 67  ? 212.104 199.350 233.191 1.00 59.33  ? 73  ILE J C     1 
ATOM   486  O O     . ILE A 1 67  ? 211.708 198.353 233.806 1.00 59.33  ? 73  ILE J O     1 
ATOM   487  C CB    . ILE A 1 67  ? 214.285 198.447 232.311 1.00 59.33  ? 73  ILE J CB    1 
ATOM   488  C CG1   . ILE A 1 67  ? 215.798 198.633 232.343 1.00 59.33  ? 73  ILE J CG1   1 
ATOM   489  C CG2   . ILE A 1 67  ? 213.806 198.349 230.881 1.00 59.33  ? 73  ILE J CG2   1 
ATOM   490  C CD1   . ILE A 1 67  ? 216.550 197.636 231.507 1.00 59.33  ? 73  ILE J CD1   1 
ATOM   491  N N     . GLU A 1 68  ? 211.279 200.237 232.638 1.00 65.16  ? 74  GLU J N     1 
ATOM   492  C CA    . GLU A 1 68  ? 209.840 200.159 232.858 1.00 65.16  ? 74  GLU J CA    1 
ATOM   493  C C     . GLU A 1 68  ? 209.142 199.315 231.796 1.00 65.16  ? 74  GLU J C     1 
ATOM   494  O O     . GLU A 1 68  ? 208.518 198.299 232.114 1.00 65.16  ? 74  GLU J O     1 
ATOM   495  C CB    . GLU A 1 68  ? 209.243 201.570 232.896 1.00 65.16  ? 74  GLU J CB    1 
ATOM   496  C CG    . GLU A 1 68  ? 209.256 202.213 234.271 1.00 65.16  ? 74  GLU J CG    1 
ATOM   497  C CD    . GLU A 1 68  ? 208.628 201.332 235.333 1.00 65.16  ? 74  GLU J CD    1 
ATOM   498  O OE1   . GLU A 1 68  ? 209.368 200.577 235.998 1.00 65.16  ? 74  GLU J OE1   1 
ATOM   499  O OE2   . GLU A 1 68  ? 207.392 201.391 235.501 1.00 65.16  ? 74  GLU J OE2   1 
ATOM   500  N N     . HIS A 1 69  ? 209.240 199.721 230.535 1.00 63.87  ? 75  HIS J N     1 
ATOM   501  C CA    . HIS A 1 69  ? 208.589 199.030 229.428 1.00 63.87  ? 75  HIS J CA    1 
ATOM   502  C C     . HIS A 1 69  ? 209.565 198.852 228.279 1.00 63.87  ? 75  HIS J C     1 
ATOM   503  O O     . HIS A 1 69  ? 209.261 199.121 227.116 1.00 63.87  ? 75  HIS J O     1 
ATOM   504  C CB    . HIS A 1 69  ? 207.343 199.784 228.981 1.00 63.87  ? 75  HIS J CB    1 
ATOM   505  C CG    . HIS A 1 69  ? 206.161 199.571 229.873 1.00 63.87  ? 75  HIS J CG    1 
ATOM   506  N ND1   . HIS A 1 69  ? 205.342 200.600 230.283 1.00 63.87  ? 75  HIS J ND1   1 
ATOM   507  C CD2   . HIS A 1 69  ? 205.665 198.447 230.441 1.00 63.87  ? 75  HIS J CD2   1 
ATOM   508  C CE1   . HIS A 1 69  ? 204.391 200.119 231.062 1.00 63.87  ? 75  HIS J CE1   1 
ATOM   509  N NE2   . HIS A 1 69  ? 204.564 198.815 231.174 1.00 63.87  ? 75  HIS J NE2   1 
ATOM   510  N N     . GLY A 1 70  ? 210.769 198.391 228.602 1.00 59.99  ? 76  GLY J N     1 
ATOM   511  C CA    . GLY A 1 70  ? 211.847 198.352 227.646 1.00 59.99  ? 76  GLY J CA    1 
ATOM   512  C C     . GLY A 1 70  ? 212.604 199.648 227.505 1.00 59.99  ? 76  GLY J C     1 
ATOM   513  O O     . GLY A 1 70  ? 213.619 199.679 226.801 1.00 59.99  ? 76  GLY J O     1 
ATOM   514  N N     . ILE A 1 71  ? 212.151 200.718 228.151 1.00 58.10  ? 77  ILE J N     1 
ATOM   515  C CA    . ILE A 1 71  ? 212.806 202.017 228.103 1.00 58.10  ? 77  ILE J CA    1 
ATOM   516  C C     . ILE A 1 71  ? 213.446 202.277 229.457 1.00 58.10  ? 77  ILE J C     1 
ATOM   517  O O     . ILE A 1 71  ? 212.776 202.197 230.492 1.00 58.10  ? 77  ILE J O     1 
ATOM   518  C CB    . ILE A 1 71  ? 211.812 203.134 227.748 1.00 58.10  ? 77  ILE J CB    1 
ATOM   519  C CG1   . ILE A 1 71  ? 210.885 202.679 226.627 1.00 58.10  ? 77  ILE J CG1   1 
ATOM   520  C CG2   . ILE A 1 71  ? 212.550 204.390 227.344 1.00 58.10  ? 77  ILE J CG2   1 
ATOM   521  C CD1   . ILE A 1 71  ? 209.657 203.534 226.480 1.00 58.10  ? 77  ILE J CD1   1 
ATOM   522  N N     . ILE A 1 72  ? 214.734 202.595 229.449 1.00 58.16  ? 78  ILE J N     1 
ATOM   523  C CA    . ILE A 1 72  ? 215.454 202.915 230.675 1.00 58.16  ? 78  ILE J CA    1 
ATOM   524  C C     . ILE A 1 72  ? 214.994 204.282 231.161 1.00 58.16  ? 78  ILE J C     1 
ATOM   525  O O     . ILE A 1 72  ? 215.165 205.288 230.466 1.00 58.16  ? 78  ILE J O     1 
ATOM   526  C CB    . ILE A 1 72  ? 216.970 202.888 230.444 1.00 58.16  ? 78  ILE J CB    1 
ATOM   527  C CG1   . ILE A 1 72  ? 217.413 201.478 230.053 1.00 58.16  ? 78  ILE J CG1   1 
ATOM   528  C CG2   . ILE A 1 72  ? 217.704 203.353 231.677 1.00 58.16  ? 78  ILE J CG2   1 
ATOM   529  C CD1   . ILE A 1 72  ? 218.814 201.402 229.526 1.00 58.16  ? 78  ILE J CD1   1 
ATOM   530  N N     . THR A 1 73  ? 214.406 204.323 232.356 1.00 60.94  ? 79  THR J N     1 
ATOM   531  C CA    . THR A 1 73  ? 213.871 205.559 232.906 1.00 60.94  ? 79  THR J CA    1 
ATOM   532  C C     . THR A 1 73  ? 214.704 206.127 234.043 1.00 60.94  ? 79  THR J C     1 
ATOM   533  O O     . THR A 1 73  ? 214.559 207.312 234.358 1.00 60.94  ? 79  THR J O     1 
ATOM   534  C CB    . THR A 1 73  ? 212.437 205.348 233.407 1.00 60.94  ? 79  THR J CB    1 
ATOM   535  O OG1   . THR A 1 73  ? 212.446 204.425 234.501 1.00 60.94  ? 79  THR J OG1   1 
ATOM   536  C CG2   . THR A 1 73  ? 211.571 204.787 232.299 1.00 60.94  ? 79  THR J CG2   1 
ATOM   537  N N     . ASN A 1 74  ? 215.565 205.326 234.662 1.00 61.46  ? 80  ASN J N     1 
ATOM   538  C CA    . ASN A 1 74  ? 216.476 205.806 235.697 1.00 61.46  ? 80  ASN J CA    1 
ATOM   539  C C     . ASN A 1 74  ? 217.879 205.417 235.264 1.00 61.46  ? 80  ASN J C     1 
ATOM   540  O O     . ASN A 1 74  ? 218.216 204.231 235.245 1.00 61.46  ? 80  ASN J O     1 
ATOM   541  C CB    . ASN A 1 74  ? 216.134 205.216 237.063 1.00 61.46  ? 80  ASN J CB    1 
ATOM   542  C CG    . ASN A 1 74  ? 216.786 205.970 238.201 1.00 61.46  ? 80  ASN J CG    1 
ATOM   543  O OD1   . ASN A 1 74  ? 217.702 206.762 237.992 1.00 61.46  ? 80  ASN J OD1   1 
ATOM   544  N ND2   . ASN A 1 74  ? 216.312 205.732 239.416 1.00 61.46  ? 80  ASN J ND2   1 
ATOM   545  N N     . TRP A 1 75  ? 218.694 206.407 234.913 1.00 60.37  ? 81  TRP J N     1 
ATOM   546  C CA    . TRP A 1 75  ? 219.970 206.118 234.276 1.00 60.37  ? 81  TRP J CA    1 
ATOM   547  C C     . TRP A 1 75  ? 221.099 205.886 235.267 1.00 60.37  ? 81  TRP J C     1 
ATOM   548  O O     . TRP A 1 75  ? 222.022 205.121 234.966 1.00 60.37  ? 81  TRP J O     1 
ATOM   549  C CB    . TRP A 1 75  ? 220.334 207.243 233.308 1.00 60.37  ? 81  TRP J CB    1 
ATOM   550  C CG    . TRP A 1 75  ? 219.738 207.007 231.966 1.00 60.37  ? 81  TRP J CG    1 
ATOM   551  C CD1   . TRP A 1 75  ? 218.647 207.623 231.432 1.00 60.37  ? 81  TRP J CD1   1 
ATOM   552  C CD2   . TRP A 1 75  ? 220.173 206.050 230.999 1.00 60.37  ? 81  TRP J CD2   1 
ATOM   553  N NE1   . TRP A 1 75  ? 218.387 207.121 230.182 1.00 60.37  ? 81  TRP J NE1   1 
ATOM   554  C CE2   . TRP A 1 75  ? 219.310 206.152 229.894 1.00 60.37  ? 81  TRP J CE2   1 
ATOM   555  C CE3   . TRP A 1 75  ? 221.216 205.123 230.956 1.00 60.37  ? 81  TRP J CE3   1 
ATOM   556  C CZ2   . TRP A 1 75  ? 219.456 205.361 228.764 1.00 60.37  ? 81  TRP J CZ2   1 
ATOM   557  C CZ3   . TRP A 1 75  ? 221.360 204.342 229.832 1.00 60.37  ? 81  TRP J CZ3   1 
ATOM   558  C CH2   . TRP A 1 75  ? 220.487 204.466 228.750 1.00 60.37  ? 81  TRP J CH2   1 
ATOM   559  N N     . ASP A 1 76  ? 221.054 206.510 236.444 1.00 64.64  ? 82  ASP J N     1 
ATOM   560  C CA    . ASP A 1 76  ? 222.053 206.198 237.460 1.00 64.64  ? 82  ASP J CA    1 
ATOM   561  C C     . ASP A 1 76  ? 221.867 204.783 237.988 1.00 64.64  ? 82  ASP J C     1 
ATOM   562  O O     . ASP A 1 76  ? 222.847 204.079 238.255 1.00 64.64  ? 82  ASP J O     1 
ATOM   563  C CB    . ASP A 1 76  ? 221.990 207.215 238.595 1.00 64.64  ? 82  ASP J CB    1 
ATOM   564  C CG    . ASP A 1 76  ? 222.739 208.489 238.271 1.00 64.64  ? 82  ASP J CG    1 
ATOM   565  O OD1   . ASP A 1 76  ? 223.021 208.722 237.078 1.00 64.64  ? 82  ASP J OD1   1 
ATOM   566  O OD2   . ASP A 1 76  ? 223.052 209.255 239.206 1.00 64.64  ? 82  ASP J OD2   1 
ATOM   567  N N     . ASP A 1 77  ? 220.618 204.341 238.128 1.00 63.20  ? 83  ASP J N     1 
ATOM   568  C CA    . ASP A 1 77  ? 220.370 202.961 238.524 1.00 63.20  ? 83  ASP J CA    1 
ATOM   569  C C     . ASP A 1 77  ? 220.860 201.989 237.459 1.00 63.20  ? 83  ASP J C     1 
ATOM   570  O O     . ASP A 1 77  ? 221.410 200.928 237.779 1.00 63.20  ? 83  ASP J O     1 
ATOM   571  C CB    . ASP A 1 77  ? 218.883 202.755 238.796 1.00 63.20  ? 83  ASP J CB    1 
ATOM   572  C CG    . ASP A 1 77  ? 218.406 203.509 240.018 1.00 63.20  ? 83  ASP J CG    1 
ATOM   573  O OD1   . ASP A 1 77  ? 219.212 204.261 240.605 1.00 63.20  ? 83  ASP J OD1   1 
ATOM   574  O OD2   . ASP A 1 77  ? 217.226 203.353 240.392 1.00 63.20  ? 83  ASP J OD2   1 
ATOM   575  N N     . MET A 1 78  ? 220.674 202.334 236.184 1.00 62.27  ? 84  MET J N     1 
ATOM   576  C CA    . MET A 1 78  ? 221.174 201.473 235.120 1.00 62.27  ? 84  MET J CA    1 
ATOM   577  C C     . MET A 1 78  ? 222.695 201.446 235.113 1.00 62.27  ? 84  MET J C     1 
ATOM   578  O O     . MET A 1 78  ? 223.301 200.405 234.839 1.00 62.27  ? 84  MET J O     1 
ATOM   579  C CB    . MET A 1 78  ? 220.635 201.930 233.768 1.00 62.27  ? 84  MET J CB    1 
ATOM   580  C CG    . MET A 1 78  ? 220.490 200.802 232.772 1.00 62.27  ? 84  MET J CG    1 
ATOM   581  S SD    . MET A 1 78  ? 219.603 199.409 233.485 1.00 62.27  ? 84  MET J SD    1 
ATOM   582  C CE    . MET A 1 78  ? 220.111 198.081 232.400 1.00 62.27  ? 84  MET J CE    1 
ATOM   583  N N     . GLU A 1 79  ? 223.330 202.576 235.424 1.00 63.27  ? 85  GLU J N     1 
ATOM   584  C CA    . GLU A 1 79  ? 224.781 202.586 235.553 1.00 63.27  ? 85  GLU J CA    1 
ATOM   585  C C     . GLU A 1 79  ? 225.231 201.692 236.700 1.00 63.27  ? 85  GLU J C     1 
ATOM   586  O O     . GLU A 1 79  ? 226.218 200.960 236.575 1.00 63.27  ? 85  GLU J O     1 
ATOM   587  C CB    . GLU A 1 79  ? 225.273 204.020 235.744 1.00 63.27  ? 85  GLU J CB    1 
ATOM   588  C CG    . GLU A 1 79  ? 226.775 204.202 235.632 1.00 63.27  ? 85  GLU J CG    1 
ATOM   589  C CD    . GLU A 1 79  ? 227.496 203.958 236.943 1.00 63.27  ? 85  GLU J CD    1 
ATOM   590  O OE1   . GLU A 1 79  ? 226.881 204.162 238.010 1.00 63.27  ? 85  GLU J OE1   1 
ATOM   591  O OE2   . GLU A 1 79  ? 228.682 203.567 236.908 1.00 63.27  ? 85  GLU J OE2   1 
ATOM   592  N N     . LYS A 1 80  ? 224.512 201.731 237.824 1.00 61.79  ? 86  LYS J N     1 
ATOM   593  C CA    . LYS A 1 80  ? 224.835 200.852 238.945 1.00 61.79  ? 86  LYS J CA    1 
ATOM   594  C C     . LYS A 1 80  ? 224.710 199.387 238.553 1.00 61.79  ? 86  LYS J C     1 
ATOM   595  O O     . LYS A 1 80  ? 225.570 198.568 238.897 1.00 61.79  ? 86  LYS J O     1 
ATOM   596  C CB    . LYS A 1 80  ? 223.926 201.153 240.134 1.00 61.79  ? 86  LYS J CB    1 
ATOM   597  C CG    . LYS A 1 80  ? 224.170 202.491 240.790 1.00 61.79  ? 86  LYS J CG    1 
ATOM   598  C CD    . LYS A 1 80  ? 223.324 202.644 242.037 1.00 61.79  ? 86  LYS J CD    1 
ATOM   599  C CE    . LYS A 1 80  ? 223.348 204.076 242.528 1.00 61.79  ? 86  LYS J CE    1 
ATOM   600  N NZ    . LYS A 1 80  ? 224.734 204.614 242.568 1.00 61.79  ? 86  LYS J NZ    1 
ATOM   601  N N     . ILE A 1 81  ? 223.642 199.037 237.837 1.00 59.84  ? 87  ILE J N     1 
ATOM   602  C CA    . ILE A 1 81  ? 223.440 197.647 237.441 1.00 59.84  ? 87  ILE J CA    1 
ATOM   603  C C     . ILE A 1 81  ? 224.512 197.203 236.455 1.00 59.84  ? 87  ILE J C     1 
ATOM   604  O O     . ILE A 1 81  ? 225.019 196.080 236.538 1.00 59.84  ? 87  ILE J O     1 
ATOM   605  C CB    . ILE A 1 81  ? 222.023 197.445 236.880 1.00 59.84  ? 87  ILE J CB    1 
ATOM   606  C CG1   . ILE A 1 81  ? 220.999 197.565 238.004 1.00 59.84  ? 87  ILE J CG1   1 
ATOM   607  C CG2   . ILE A 1 81  ? 221.892 196.102 236.206 1.00 59.84  ? 87  ILE J CG2   1 
ATOM   608  C CD1   . ILE A 1 81  ? 219.592 197.537 237.532 1.00 59.84  ? 87  ILE J CD1   1 
ATOM   609  N N     . TRP A 1 82  ? 224.881 198.070 235.512 1.00 59.29  ? 88  TRP J N     1 
ATOM   610  C CA    . TRP A 1 82  ? 225.941 197.721 234.572 1.00 59.29  ? 88  TRP J CA    1 
ATOM   611  C C     . TRP A 1 82  ? 227.275 197.540 235.283 1.00 59.29  ? 88  TRP J C     1 
ATOM   612  O O     . TRP A 1 82  ? 228.021 196.599 234.987 1.00 59.29  ? 88  TRP J O     1 
ATOM   613  C CB    . TRP A 1 82  ? 226.056 198.792 233.494 1.00 59.29  ? 88  TRP J CB    1 
ATOM   614  C CG    . TRP A 1 82  ? 225.192 198.540 232.314 1.00 59.29  ? 88  TRP J CG    1 
ATOM   615  C CD1   . TRP A 1 82  ? 224.856 197.331 231.789 1.00 59.29  ? 88  TRP J CD1   1 
ATOM   616  C CD2   . TRP A 1 82  ? 224.546 199.524 231.505 1.00 59.29  ? 88  TRP J CD2   1 
ATOM   617  N NE1   . TRP A 1 82  ? 224.040 197.499 230.701 1.00 59.29  ? 88  TRP J NE1   1 
ATOM   618  C CE2   . TRP A 1 82  ? 223.834 198.839 230.507 1.00 59.29  ? 88  TRP J CE2   1 
ATOM   619  C CE3   . TRP A 1 82  ? 224.499 200.918 231.530 1.00 59.29  ? 88  TRP J CE3   1 
ATOM   620  C CZ2   . TRP A 1 82  ? 223.086 199.499 229.542 1.00 59.29  ? 88  TRP J CZ2   1 
ATOM   621  C CZ3   . TRP A 1 82  ? 223.756 201.571 230.572 1.00 59.29  ? 88  TRP J CZ3   1 
ATOM   622  C CH2   . TRP A 1 82  ? 223.060 200.863 229.591 1.00 59.29  ? 88  TRP J CH2   1 
ATOM   623  N N     . HIS A 1 83  ? 227.599 198.443 236.209 1.00 61.93  ? 89  HIS J N     1 
ATOM   624  C CA    . HIS A 1 83  ? 228.831 198.319 236.978 1.00 61.93  ? 89  HIS J CA    1 
ATOM   625  C C     . HIS A 1 83  ? 228.858 197.013 237.757 1.00 61.93  ? 89  HIS J C     1 
ATOM   626  O O     . HIS A 1 83  ? 229.880 196.316 237.785 1.00 61.93  ? 89  HIS J O     1 
ATOM   627  C CB    . HIS A 1 83  ? 228.964 199.516 237.916 1.00 61.93  ? 89  HIS J CB    1 
ATOM   628  C CG    . HIS A 1 83  ? 230.238 199.543 238.696 1.00 61.93  ? 89  HIS J CG    1 
ATOM   629  N ND1   . HIS A 1 83  ? 231.206 200.502 238.499 1.00 61.93  ? 89  HIS J ND1   1 
ATOM   630  C CD2   . HIS A 1 83  ? 230.697 198.741 239.684 1.00 61.93  ? 89  HIS J CD2   1 
ATOM   631  C CE1   . HIS A 1 83  ? 232.211 200.285 239.327 1.00 61.93  ? 89  HIS J CE1   1 
ATOM   632  N NE2   . HIS A 1 83  ? 231.928 199.222 240.057 1.00 61.93  ? 89  HIS J NE2   1 
ATOM   633  N N     . HIS A 1 84  ? 227.743 196.671 238.404 1.00 60.02  ? 90  HIS J N     1 
ATOM   634  C CA    . HIS A 1 84  ? 227.651 195.395 239.101 1.00 60.02  ? 90  HIS J CA    1 
ATOM   635  C C     . HIS A 1 84  ? 227.892 194.237 238.145 1.00 60.02  ? 90  HIS J C     1 
ATOM   636  O O     . HIS A 1 84  ? 228.745 193.381 238.396 1.00 60.02  ? 90  HIS J O     1 
ATOM   637  C CB    . HIS A 1 84  ? 226.287 195.264 239.770 1.00 60.02  ? 90  HIS J CB    1 
ATOM   638  C CG    . HIS A 1 84  ? 226.116 194.003 240.554 1.00 60.02  ? 90  HIS J CG    1 
ATOM   639  N ND1   . HIS A 1 84  ? 226.669 193.825 241.802 1.00 60.02  ? 90  HIS J ND1   1 
ATOM   640  C CD2   . HIS A 1 84  ? 225.447 192.862 240.272 1.00 60.02  ? 90  HIS J CD2   1 
ATOM   641  C CE1   . HIS A 1 84  ? 226.351 192.625 242.254 1.00 60.02  ? 90  HIS J CE1   1 
ATOM   642  N NE2   . HIS A 1 84  ? 225.609 192.021 241.345 1.00 60.02  ? 90  HIS J NE2   1 
ATOM   643  N N     . THR A 1 85  ? 227.162 194.211 237.030 1.00 59.15  ? 91  THR J N     1 
ATOM   644  C CA    . THR A 1 85  ? 227.320 193.145 236.048 1.00 59.15  ? 91  THR J CA    1 
ATOM   645  C C     . THR A 1 85  ? 228.773 192.978 235.638 1.00 59.15  ? 91  THR J C     1 
ATOM   646  O O     . THR A 1 85  ? 229.284 191.856 235.568 1.00 59.15  ? 91  THR J O     1 
ATOM   647  C CB    . THR A 1 85  ? 226.465 193.440 234.818 1.00 59.15  ? 91  THR J CB    1 
ATOM   648  O OG1   . THR A 1 85  ? 225.080 193.388 235.169 1.00 59.15  ? 91  THR J OG1   1 
ATOM   649  C CG2   . THR A 1 85  ? 226.736 192.429 233.733 1.00 59.15  ? 91  THR J CG2   1 
ATOM   650  N N     . PHE A 1 86  ? 229.459 194.087 235.378 1.00 61.35  ? 92  PHE J N     1 
ATOM   651  C CA    . PHE A 1 86  ? 230.820 193.996 234.865 1.00 61.35  ? 92  PHE J CA    1 
ATOM   652  C C     . PHE A 1 86  ? 231.798 193.531 235.936 1.00 61.35  ? 92  PHE J C     1 
ATOM   653  O O     . PHE A 1 86  ? 232.644 192.671 235.672 1.00 61.35  ? 92  PHE J O     1 
ATOM   654  C CB    . PHE A 1 86  ? 231.253 195.340 234.288 1.00 61.35  ? 92  PHE J CB    1 
ATOM   655  C CG    . PHE A 1 86  ? 230.679 195.624 232.936 1.00 61.35  ? 92  PHE J CG    1 
ATOM   656  C CD1   . PHE A 1 86  ? 230.437 194.596 232.047 1.00 61.35  ? 92  PHE J CD1   1 
ATOM   657  C CD2   . PHE A 1 86  ? 230.374 196.913 232.556 1.00 61.35  ? 92  PHE J CD2   1 
ATOM   658  C CE1   . PHE A 1 86  ? 229.906 194.850 230.805 1.00 61.35  ? 92  PHE J CE1   1 
ATOM   659  C CE2   . PHE A 1 86  ? 229.842 197.172 231.313 1.00 61.35  ? 92  PHE J CE2   1 
ATOM   660  C CZ    . PHE A 1 86  ? 229.607 196.139 230.438 1.00 61.35  ? 92  PHE J CZ    1 
ATOM   661  N N     . TYR A 1 87  ? 231.703 194.074 237.148 1.00 65.07  ? 93  TYR J N     1 
ATOM   662  C CA    . TYR A 1 87  ? 232.765 193.859 238.123 1.00 65.07  ? 93  TYR J CA    1 
ATOM   663  C C     . TYR A 1 87  ? 232.470 192.769 239.145 1.00 65.07  ? 93  TYR J C     1 
ATOM   664  O O     . TYR A 1 87  ? 233.383 192.029 239.516 1.00 65.07  ? 93  TYR J O     1 
ATOM   665  C CB    . TYR A 1 87  ? 233.082 195.168 238.846 1.00 65.07  ? 93  TYR J CB    1 
ATOM   666  C CG    . TYR A 1 87  ? 233.634 196.227 237.923 1.00 65.07  ? 93  TYR J CG    1 
ATOM   667  C CD1   . TYR A 1 87  ? 234.996 196.341 237.703 1.00 65.07  ? 93  TYR J CD1   1 
ATOM   668  C CD2   . TYR A 1 87  ? 232.793 197.103 237.260 1.00 65.07  ? 93  TYR J CD2   1 
ATOM   669  C CE1   . TYR A 1 87  ? 235.502 197.304 236.854 1.00 65.07  ? 93  TYR J CE1   1 
ATOM   670  C CE2   . TYR A 1 87  ? 233.289 198.068 236.412 1.00 65.07  ? 93  TYR J CE2   1 
ATOM   671  C CZ    . TYR A 1 87  ? 234.642 198.165 236.212 1.00 65.07  ? 93  TYR J CZ    1 
ATOM   672  O OH    . TYR A 1 87  ? 235.136 199.128 235.365 1.00 65.07  ? 93  TYR J OH    1 
ATOM   673  N N     . ASN A 1 88  ? 231.234 192.636 239.620 1.00 65.11  ? 94  ASN J N     1 
ATOM   674  C CA    . ASN A 1 88  ? 230.951 191.711 240.706 1.00 65.11  ? 94  ASN J CA    1 
ATOM   675  C C     . ASN A 1 88  ? 230.379 190.382 240.241 1.00 65.11  ? 94  ASN J C     1 
ATOM   676  O O     . ASN A 1 88  ? 230.547 189.375 240.934 1.00 65.11  ? 94  ASN J O     1 
ATOM   677  C CB    . ASN A 1 88  ? 229.979 192.353 241.698 1.00 65.11  ? 94  ASN J CB    1 
ATOM   678  C CG    . ASN A 1 88  ? 230.593 193.522 242.430 1.00 65.11  ? 94  ASN J CG    1 
ATOM   679  O OD1   . ASN A 1 88  ? 231.757 193.478 242.821 1.00 65.11  ? 94  ASN J OD1   1 
ATOM   680  N ND2   . ASN A 1 88  ? 229.815 194.577 242.617 1.00 65.11  ? 94  ASN J ND2   1 
ATOM   681  N N     . GLU A 1 89  ? 229.708 190.348 239.092 1.00 64.49  ? 95  GLU J N     1 
ATOM   682  C CA    . GLU A 1 89  ? 229.143 189.114 238.560 1.00 64.49  ? 95  GLU J CA    1 
ATOM   683  C C     . GLU A 1 89  ? 230.034 188.473 237.505 1.00 64.49  ? 95  GLU J C     1 
ATOM   684  O O     . GLU A 1 89  ? 230.350 187.284 237.599 1.00 64.49  ? 95  GLU J O     1 
ATOM   685  C CB    . GLU A 1 89  ? 227.752 189.379 237.977 1.00 64.49  ? 95  GLU J CB    1 
ATOM   686  C CG    . GLU A 1 89  ? 226.718 189.772 239.012 1.00 64.49  ? 95  GLU J CG    1 
ATOM   687  C CD    . GLU A 1 89  ? 226.309 188.613 239.895 1.00 64.49  ? 95  GLU J CD    1 
ATOM   688  O OE1   . GLU A 1 89  ? 226.542 187.451 239.502 1.00 64.49  ? 95  GLU J OE1   1 
ATOM   689  O OE2   . GLU A 1 89  ? 225.755 188.861 240.986 1.00 64.49  ? 95  GLU J OE2   1 
ATOM   690  N N     . LEU A 1 90  ? 230.445 189.240 236.496 1.00 63.08  ? 96  LEU J N     1 
ATOM   691  C CA    . LEU A 1 90  ? 231.358 188.718 235.489 1.00 63.08  ? 96  LEU J CA    1 
ATOM   692  C C     . LEU A 1 90  ? 232.806 188.771 235.950 1.00 63.08  ? 96  LEU J C     1 
ATOM   693  O O     . LEU A 1 90  ? 233.588 187.874 235.617 1.00 63.08  ? 96  LEU J O     1 
ATOM   694  C CB    . LEU A 1 90  ? 231.202 189.494 234.183 1.00 63.08  ? 96  LEU J CB    1 
ATOM   695  C CG    . LEU A 1 90  ? 229.951 189.206 233.359 1.00 63.08  ? 96  LEU J CG    1 
ATOM   696  C CD1   . LEU A 1 90  ? 229.982 189.994 232.067 1.00 63.08  ? 96  LEU J CD1   1 
ATOM   697  C CD2   . LEU A 1 90  ? 229.840 187.724 233.083 1.00 63.08  ? 96  LEU J CD2   1 
ATOM   698  N N     . ARG A 1 91  ? 233.173 189.805 236.709 1.00 68.57  ? 97  ARG J N     1 
ATOM   699  C CA    . ARG A 1 91  ? 234.542 190.024 237.177 1.00 68.57  ? 97  ARG J CA    1 
ATOM   700  C C     . ARG A 1 91  ? 235.501 190.185 235.997 1.00 68.57  ? 97  ARG J C     1 
ATOM   701  O O     . ARG A 1 91  ? 236.463 189.435 235.830 1.00 68.57  ? 97  ARG J O     1 
ATOM   702  C CB    . ARG A 1 91  ? 234.995 188.897 238.111 1.00 68.57  ? 97  ARG J CB    1 
ATOM   703  C CG    . ARG A 1 91  ? 234.086 188.679 239.307 1.00 68.57  ? 97  ARG J CG    1 
ATOM   704  C CD    . ARG A 1 91  ? 234.273 187.292 239.895 1.00 68.57  ? 97  ARG J CD    1 
ATOM   705  N NE    . ARG A 1 91  ? 234.140 186.248 238.884 1.00 68.57  ? 97  ARG J NE    1 
ATOM   706  C CZ    . ARG A 1 91  ? 234.834 185.114 238.885 1.00 68.57  ? 97  ARG J CZ    1 
ATOM   707  N NH1   . ARG A 1 91  ? 235.716 184.875 239.844 1.00 68.57  ? 97  ARG J NH1   1 
ATOM   708  N NH2   . ARG A 1 91  ? 234.649 184.219 237.923 1.00 68.57  ? 97  ARG J NH2   1 
ATOM   709  N N     . VAL A 1 92  ? 235.214 191.189 235.172 1.00 66.96  ? 98  VAL J N     1 
ATOM   710  C CA    . VAL A 1 92  ? 236.029 191.536 234.021 1.00 66.96  ? 98  VAL J CA    1 
ATOM   711  C C     . VAL A 1 92  ? 236.383 193.016 234.101 1.00 66.96  ? 98  VAL J C     1 
ATOM   712  O O     . VAL A 1 92  ? 236.011 193.716 235.040 1.00 66.96  ? 98  VAL J O     1 
ATOM   713  C CB    . VAL A 1 92  ? 235.326 191.219 232.686 1.00 66.96  ? 98  VAL J CB    1 
ATOM   714  C CG1   . VAL A 1 92  ? 234.917 189.765 232.636 1.00 66.96  ? 98  VAL J CG1   1 
ATOM   715  C CG2   . VAL A 1 92  ? 234.122 192.123 232.494 1.00 66.96  ? 98  VAL J CG2   1 
ATOM   716  N N     . ALA A 1 93  ? 237.118 193.483 233.097 1.00 68.44  ? 99  ALA J N     1 
ATOM   717  C CA    . ALA A 1 93  ? 237.400 194.899 232.916 1.00 68.44  ? 99  ALA J CA    1 
ATOM   718  C C     . ALA A 1 93  ? 236.847 195.315 231.562 1.00 68.44  ? 99  ALA J C     1 
ATOM   719  O O     . ALA A 1 93  ? 237.312 194.806 230.528 1.00 68.44  ? 99  ALA J O     1 
ATOM   720  C CB    . ALA A 1 93  ? 238.898 195.185 232.998 1.00 68.44  ? 99  ALA J CB    1 
ATOM   721  N N     . PRO A 1 94  ? 235.869 196.220 231.507 1.00 67.65  ? 100 PRO J N     1 
ATOM   722  C CA    . PRO A 1 94  ? 235.205 196.504 230.225 1.00 67.65  ? 100 PRO J CA    1 
ATOM   723  C C     . PRO A 1 94  ? 236.110 197.144 229.190 1.00 67.65  ? 100 PRO J C     1 
ATOM   724  O O     . PRO A 1 94  ? 235.762 197.128 228.004 1.00 67.65  ? 100 PRO J O     1 
ATOM   725  C CB    . PRO A 1 94  ? 234.059 197.447 230.622 1.00 67.65  ? 100 PRO J CB    1 
ATOM   726  C CG    . PRO A 1 94  ? 233.942 197.333 232.111 1.00 67.65  ? 100 PRO J CG    1 
ATOM   727  C CD    . PRO A 1 94  ? 235.308 197.015 232.608 1.00 67.65  ? 100 PRO J CD    1 
ATOM   728  N N     . GLU A 1 95  ? 237.255 197.703 229.587 1.00 69.54  ? 101 GLU J N     1 
ATOM   729  C CA    . GLU A 1 95  ? 238.160 198.316 228.623 1.00 69.54  ? 101 GLU J CA    1 
ATOM   730  C C     . GLU A 1 95  ? 238.828 197.298 227.712 1.00 69.54  ? 101 GLU J C     1 
ATOM   731  O O     . GLU A 1 95  ? 239.476 197.695 226.739 1.00 69.54  ? 101 GLU J O     1 
ATOM   732  C CB    . GLU A 1 95  ? 239.239 199.126 229.342 1.00 69.54  ? 101 GLU J CB    1 
ATOM   733  C CG    . GLU A 1 95  ? 238.712 200.264 230.190 1.00 69.54  ? 101 GLU J CG    1 
ATOM   734  C CD    . GLU A 1 95  ? 238.332 199.817 231.585 1.00 69.54  ? 101 GLU J CD    1 
ATOM   735  O OE1   . GLU A 1 95  ? 238.565 198.634 231.910 1.00 69.54  ? 101 GLU J OE1   1 
ATOM   736  O OE2   . GLU A 1 95  ? 237.803 200.645 232.355 1.00 69.54  ? 101 GLU J OE2   1 
ATOM   737  N N     . GLU A 1 96  ? 238.682 196.006 227.997 1.00 73.52  ? 102 GLU J N     1 
ATOM   738  C CA    . GLU A 1 96  ? 239.354 194.958 227.243 1.00 73.52  ? 102 GLU J CA    1 
ATOM   739  C C     . GLU A 1 96  ? 238.382 194.054 226.497 1.00 73.52  ? 102 GLU J C     1 
ATOM   740  O O     . GLU A 1 96  ? 238.804 193.028 225.951 1.00 73.52  ? 102 GLU J O     1 
ATOM   741  C CB    . GLU A 1 96  ? 240.214 194.116 228.186 1.00 73.52  ? 102 GLU J CB    1 
ATOM   742  C CG    . GLU A 1 96  ? 241.328 194.887 228.859 1.00 73.52  ? 102 GLU J CG    1 
ATOM   743  C CD    . GLU A 1 96  ? 242.114 194.029 229.825 1.00 73.52  ? 102 GLU J CD    1 
ATOM   744  O OE1   . GLU A 1 96  ? 241.714 192.867 230.048 1.00 73.52  ? 102 GLU J OE1   1 
ATOM   745  O OE2   . GLU A 1 96  ? 243.130 194.515 230.365 1.00 73.52  ? 102 GLU J OE2   1 
ATOM   746  N N     . HIS A 1 97  ? 237.095 194.402 226.454 1.00 66.72  ? 103 HIS J N     1 
ATOM   747  C CA    . HIS A 1 97  ? 236.085 193.516 225.907 1.00 66.72  ? 103 HIS J CA    1 
ATOM   748  C C     . HIS A 1 97  ? 235.059 194.292 225.090 1.00 66.72  ? 103 HIS J C     1 
ATOM   749  O O     . HIS A 1 97  ? 234.457 195.247 225.607 1.00 66.72  ? 103 HIS J O     1 
ATOM   750  C CB    . HIS A 1 97  ? 235.382 192.758 227.034 1.00 66.72  ? 103 HIS J CB    1 
ATOM   751  C CG    . HIS A 1 97  ? 236.204 191.662 227.633 1.00 66.72  ? 103 HIS J CG    1 
ATOM   752  N ND1   . HIS A 1 97  ? 236.720 191.733 228.907 1.00 66.72  ? 103 HIS J ND1   1 
ATOM   753  C CD2   . HIS A 1 97  ? 236.589 190.464 227.137 1.00 66.72  ? 103 HIS J CD2   1 
ATOM   754  C CE1   . HIS A 1 97  ? 237.393 190.629 229.169 1.00 66.72  ? 103 HIS J CE1   1 
ATOM   755  N NE2   . HIS A 1 97  ? 237.329 189.842 228.111 1.00 66.72  ? 103 HIS J NE2   1 
ATOM   756  N N     . PRO A 1 98  ? 234.836 193.921 223.833 1.00 59.94  ? 104 PRO J N     1 
ATOM   757  C CA    . PRO A 1 98  ? 233.668 194.441 223.116 1.00 59.94  ? 104 PRO J CA    1 
ATOM   758  C C     . PRO A 1 98  ? 232.387 193.892 223.724 1.00 59.94  ? 104 PRO J C     1 
ATOM   759  O O     . PRO A 1 98  ? 232.316 192.725 224.112 1.00 59.94  ? 104 PRO J O     1 
ATOM   760  C CB    . PRO A 1 98  ? 233.874 193.935 221.684 1.00 59.94  ? 104 PRO J CB    1 
ATOM   761  C CG    . PRO A 1 98  ? 235.311 193.558 221.606 1.00 59.94  ? 104 PRO J CG    1 
ATOM   762  C CD    . PRO A 1 98  ? 235.694 193.101 222.967 1.00 59.94  ? 104 PRO J CD    1 
ATOM   763  N N     . THR A 1 99  ? 231.367 194.741 223.803 1.00 57.38  ? 105 THR J N     1 
ATOM   764  C CA    . THR A 1 99  ? 230.120 194.406 224.478 1.00 57.38  ? 105 THR J CA    1 
ATOM   765  C C     . THR A 1 99  ? 228.959 194.514 223.503 1.00 57.38  ? 105 THR J C     1 
ATOM   766  O O     . THR A 1 99  ? 228.810 195.531 222.822 1.00 57.38  ? 105 THR J O     1 
ATOM   767  C CB    . THR A 1 99  ? 229.883 195.331 225.671 1.00 57.38  ? 105 THR J CB    1 
ATOM   768  O OG1   . THR A 1 99  ? 230.991 195.239 226.572 1.00 57.38  ? 105 THR J OG1   1 
ATOM   769  C CG2   . THR A 1 99  ? 228.616 194.942 226.406 1.00 57.38  ? 105 THR J CG2   1 
ATOM   770  N N     . LEU A 1 100 ? 228.131 193.475 223.448 1.00 53.66  ? 106 LEU J N     1 
ATOM   771  C CA    . LEU A 1 100 ? 226.956 193.446 222.582 1.00 53.66  ? 106 LEU J CA    1 
ATOM   772  C C     . LEU A 1 100 ? 225.716 193.642 223.444 1.00 53.66  ? 106 LEU J C     1 
ATOM   773  O O     . LEU A 1 100 ? 225.264 192.716 224.119 1.00 53.66  ? 106 LEU J O     1 
ATOM   774  C CB    . LEU A 1 100 ? 226.886 192.139 221.803 1.00 53.66  ? 106 LEU J CB    1 
ATOM   775  C CG    . LEU A 1 100 ? 225.628 191.935 220.961 1.00 53.66  ? 106 LEU J CG    1 
ATOM   776  C CD1   . LEU A 1 100 ? 225.786 192.587 219.610 1.00 53.66  ? 106 LEU J CD1   1 
ATOM   777  C CD2   . LEU A 1 100 ? 225.316 190.466 220.802 1.00 53.66  ? 106 LEU J CD2   1 
ATOM   778  N N     . LEU A 1 101 ? 225.164 194.847 223.421 1.00 56.72  ? 107 LEU J N     1 
ATOM   779  C CA    . LEU A 1 101 ? 223.916 195.127 224.107 1.00 56.72  ? 107 LEU J CA    1 
ATOM   780  C C     . LEU A 1 101 ? 222.737 194.688 223.244 1.00 56.72  ? 107 LEU J C     1 
ATOM   781  O O     . LEU A 1 101 ? 222.886 194.352 222.070 1.00 56.72  ? 107 LEU J O     1 
ATOM   782  C CB    . LEU A 1 101 ? 223.819 196.611 224.449 1.00 56.72  ? 107 LEU J CB    1 
ATOM   783  C CG    . LEU A 1 101 ? 224.940 197.123 225.350 1.00 56.72  ? 107 LEU J CG    1 
ATOM   784  C CD1   . LEU A 1 101 ? 224.898 198.628 225.463 1.00 56.72  ? 107 LEU J CD1   1 
ATOM   785  C CD2   . LEU A 1 101 ? 224.839 196.482 226.714 1.00 56.72  ? 107 LEU J CD2   1 
ATOM   786  N N     . THR A 1 102 ? 221.548 194.693 223.838 1.00 57.41  ? 108 THR J N     1 
ATOM   787  C CA    . THR A 1 102 ? 220.363 194.193 223.163 1.00 57.41  ? 108 THR J CA    1 
ATOM   788  C C     . THR A 1 102 ? 219.178 195.076 223.527 1.00 57.41  ? 108 THR J C     1 
ATOM   789  O O     . THR A 1 102 ? 219.172 195.719 224.579 1.00 57.41  ? 108 THR J O     1 
ATOM   790  C CB    . THR A 1 102 ? 220.106 192.730 223.537 1.00 57.41  ? 108 THR J CB    1 
ATOM   791  O OG1   . THR A 1 102 ? 221.334 191.999 223.444 1.00 57.41  ? 108 THR J OG1   1 
ATOM   792  C CG2   . THR A 1 102 ? 219.131 192.105 222.582 1.00 57.41  ? 108 THR J CG2   1 
ATOM   793  N N     . GLU A 1 103 ? 218.179 195.114 222.647 1.00 59.98  ? 109 GLU J N     1 
ATOM   794  C CA    . GLU A 1 103 ? 217.095 196.076 222.791 1.00 59.98  ? 109 GLU J CA    1 
ATOM   795  C C     . GLU A 1 103 ? 215.877 195.617 222.002 1.00 59.98  ? 109 GLU J C     1 
ATOM   796  O O     . GLU A 1 103 ? 215.998 194.883 221.019 1.00 59.98  ? 109 GLU J O     1 
ATOM   797  C CB    . GLU A 1 103 ? 217.542 197.459 222.313 1.00 59.98  ? 109 GLU J CB    1 
ATOM   798  C CG    . GLU A 1 103 ? 216.536 198.560 222.531 1.00 59.98  ? 109 GLU J CG    1 
ATOM   799  C CD    . GLU A 1 103 ? 217.040 199.877 222.021 1.00 59.98  ? 109 GLU J CD    1 
ATOM   800  O OE1   . GLU A 1 103 ? 218.163 199.891 221.484 1.00 59.98  ? 109 GLU J OE1   1 
ATOM   801  O OE2   . GLU A 1 103 ? 216.328 200.891 222.151 1.00 59.98  ? 109 GLU J OE2   1 
ATOM   802  N N     . ALA A 1 104 ? 214.699 196.066 222.444 1.00 58.54  ? 110 ALA J N     1 
ATOM   803  C CA    . ALA A 1 104 ? 213.445 195.829 221.750 1.00 58.54  ? 110 ALA J CA    1 
ATOM   804  C C     . ALA A 1 104 ? 213.212 196.901 220.687 1.00 58.54  ? 110 ALA J C     1 
ATOM   805  O O     . ALA A 1 104 ? 213.718 198.018 220.801 1.00 58.54  ? 110 ALA J O     1 
ATOM   806  C CB    . ALA A 1 104 ? 212.286 195.824 222.738 1.00 58.54  ? 110 ALA J CB    1 
ATOM   807  N N     . PRO A 1 105 ? 212.451 196.587 219.644 1.00 58.71  ? 111 PRO J N     1 
ATOM   808  C CA    . PRO A 1 105 ? 212.220 197.562 218.575 1.00 58.71  ? 111 PRO J CA    1 
ATOM   809  C C     . PRO A 1 105 ? 211.128 198.561 218.928 1.00 58.71  ? 111 PRO J C     1 
ATOM   810  O O     . PRO A 1 105 ? 210.304 198.342 219.816 1.00 58.71  ? 111 PRO J O     1 
ATOM   811  C CB    . PRO A 1 105 ? 211.793 196.683 217.398 1.00 58.71  ? 111 PRO J CB    1 
ATOM   812  C CG    . PRO A 1 105 ? 211.108 195.548 218.046 1.00 58.71  ? 111 PRO J CG    1 
ATOM   813  C CD    . PRO A 1 105 ? 211.879 195.273 219.308 1.00 58.71  ? 111 PRO J CD    1 
ATOM   814  N N     . LEU A 1 106 ? 211.148 199.682 218.202 1.00 60.40  ? 112 LEU J N     1 
ATOM   815  C CA    . LEU A 1 106 ? 210.131 200.733 218.305 1.00 60.40  ? 112 LEU J CA    1 
ATOM   816  C C     . LEU A 1 106 ? 210.149 201.407 219.678 1.00 60.40  ? 112 LEU J C     1 
ATOM   817  O O     . LEU A 1 106 ? 209.114 201.574 220.322 1.00 60.40  ? 112 LEU J O     1 
ATOM   818  C CB    . LEU A 1 106 ? 208.733 200.196 217.984 1.00 60.40  ? 112 LEU J CB    1 
ATOM   819  C CG    . LEU A 1 106 ? 208.500 199.622 216.588 1.00 60.40  ? 112 LEU J CG    1 
ATOM   820  C CD1   . LEU A 1 106 ? 207.083 199.109 216.461 1.00 60.40  ? 112 LEU J CD1   1 
ATOM   821  C CD2   . LEU A 1 106 ? 208.783 200.670 215.531 1.00 60.40  ? 112 LEU J CD2   1 
ATOM   822  N N     . ASN A 1 107 ? 211.335 201.793 220.123 1.00 60.08  ? 113 ASN J N     1 
ATOM   823  C CA    . ASN A 1 107 ? 211.508 202.576 221.335 1.00 60.08  ? 113 ASN J CA    1 
ATOM   824  C C     . ASN A 1 107 ? 212.453 203.729 221.039 1.00 60.08  ? 113 ASN J C     1 
ATOM   825  O O     . ASN A 1 107 ? 213.240 203.662 220.089 1.00 60.08  ? 113 ASN J O     1 
ATOM   826  C CB    . ASN A 1 107 ? 212.034 201.710 222.491 1.00 60.08  ? 113 ASN J CB    1 
ATOM   827  C CG    . ASN A 1 107 ? 213.344 201.056 222.178 1.00 60.08  ? 113 ASN J CG    1 
ATOM   828  O OD1   . ASN A 1 107 ? 213.721 200.923 221.016 1.00 60.08  ? 113 ASN J OD1   1 
ATOM   829  N ND2   . ASN A 1 107 ? 214.051 200.633 223.215 1.00 60.08  ? 113 ASN J ND2   1 
ATOM   830  N N     . PRO A 1 108 ? 212.384 204.812 221.819 1.00 58.75  ? 114 PRO J N     1 
ATOM   831  C CA    . PRO A 1 108 ? 213.050 206.062 221.428 1.00 58.75  ? 114 PRO J CA    1 
ATOM   832  C C     . PRO A 1 108 ? 214.522 205.891 221.078 1.00 58.75  ? 114 PRO J C     1 
ATOM   833  O O     . PRO A 1 108 ? 215.201 204.990 221.570 1.00 58.75  ? 114 PRO J O     1 
ATOM   834  C CB    . PRO A 1 108 ? 212.876 206.952 222.665 1.00 58.75  ? 114 PRO J CB    1 
ATOM   835  C CG    . PRO A 1 108 ? 212.415 206.036 223.754 1.00 58.75  ? 114 PRO J CG    1 
ATOM   836  C CD    . PRO A 1 108 ? 211.632 204.988 223.069 1.00 58.75  ? 114 PRO J CD    1 
ATOM   837  N N     . LYS A 1 109 ? 215.007 206.784 220.212 1.00 64.07  ? 115 LYS J N     1 
ATOM   838  C CA    . LYS A 1 109 ? 216.409 206.756 219.812 1.00 64.07  ? 115 LYS J CA    1 
ATOM   839  C C     . LYS A 1 109 ? 217.322 207.197 220.946 1.00 64.07  ? 115 LYS J C     1 
ATOM   840  O O     . LYS A 1 109 ? 218.482 206.764 221.017 1.00 64.07  ? 115 LYS J O     1 
ATOM   841  C CB    . LYS A 1 109 ? 216.624 207.653 218.596 1.00 64.07  ? 115 LYS J CB    1 
ATOM   842  C CG    . LYS A 1 109 ? 215.601 207.469 217.496 1.00 64.07  ? 115 LYS J CG    1 
ATOM   843  C CD    . LYS A 1 109 ? 215.602 206.049 216.974 1.00 64.07  ? 115 LYS J CD    1 
ATOM   844  C CE    . LYS A 1 109 ? 214.975 205.980 215.594 1.00 64.07  ? 115 LYS J CE    1 
ATOM   845  N NZ    . LYS A 1 109 ? 215.541 207.017 214.689 1.00 64.07  ? 115 LYS J NZ    1 
ATOM   846  N N     . ALA A 1 110 ? 216.823 208.066 221.829 1.00 62.80  ? 116 ALA J N     1 
ATOM   847  C CA    . ALA A 1 110 ? 217.620 208.501 222.967 1.00 62.80  ? 116 ALA J CA    1 
ATOM   848  C C     . ALA A 1 110 ? 218.078 207.321 223.806 1.00 62.80  ? 116 ALA J C     1 
ATOM   849  O O     . ALA A 1 110 ? 219.138 207.384 224.430 1.00 62.80  ? 116 ALA J O     1 
ATOM   850  C CB    . ALA A 1 110 ? 216.826 209.484 223.822 1.00 62.80  ? 116 ALA J CB    1 
ATOM   851  N N     . ASN A 1 111 ? 217.318 206.228 223.807 1.00 60.48  ? 117 ASN J N     1 
ATOM   852  C CA    . ASN A 1 111 ? 217.719 205.048 224.560 1.00 60.48  ? 117 ASN J CA    1 
ATOM   853  C C     . ASN A 1 111 ? 219.035 204.488 224.028 1.00 60.48  ? 117 ASN J C     1 
ATOM   854  O O     . ASN A 1 111 ? 219.998 204.306 224.782 1.00 60.48  ? 117 ASN J O     1 
ATOM   855  C CB    . ASN A 1 111 ? 216.609 204.001 224.503 1.00 60.48  ? 117 ASN J CB    1 
ATOM   856  C CG    . ASN A 1 111 ? 216.791 202.910 225.522 1.00 60.48  ? 117 ASN J CG    1 
ATOM   857  O OD1   . ASN A 1 111 ? 217.745 202.922 226.293 1.00 60.48  ? 117 ASN J OD1   1 
ATOM   858  N ND2   . ASN A 1 111 ? 215.876 201.952 225.534 1.00 60.48  ? 117 ASN J ND2   1 
ATOM   859  N N     . ARG A 1 112 ? 219.098 204.222 222.719 1.00 62.47  ? 118 ARG J N     1 
ATOM   860  C CA    . ARG A 1 112 ? 220.330 203.709 222.125 1.00 62.47  ? 118 ARG J CA    1 
ATOM   861  C C     . ARG A 1 112 ? 221.464 204.713 222.247 1.00 62.47  ? 118 ARG J C     1 
ATOM   862  O O     . ARG A 1 112 ? 222.613 204.335 222.509 1.00 62.47  ? 118 ARG J O     1 
ATOM   863  C CB    . ARG A 1 112 ? 220.117 203.365 220.654 1.00 62.47  ? 118 ARG J CB    1 
ATOM   864  C CG    . ARG A 1 112 ? 218.837 202.646 220.339 1.00 62.47  ? 118 ARG J CG    1 
ATOM   865  C CD    . ARG A 1 112 ? 218.523 202.753 218.862 1.00 62.47  ? 118 ARG J CD    1 
ATOM   866  N NE    . ARG A 1 112 ? 219.426 201.942 218.055 1.00 62.47  ? 118 ARG J NE    1 
ATOM   867  C CZ    . ARG A 1 112 ? 219.215 200.666 217.756 1.00 62.47  ? 118 ARG J CZ    1 
ATOM   868  N NH1   . ARG A 1 112 ? 218.131 200.048 218.200 1.00 62.47  ? 118 ARG J NH1   1 
ATOM   869  N NH2   . ARG A 1 112 ? 220.089 200.004 217.014 1.00 62.47  ? 118 ARG J NH2   1 
ATOM   870  N N     . GLU A 1 113 ? 221.168 205.998 222.042 1.00 66.15  ? 119 GLU J N     1 
ATOM   871  C CA    . GLU A 1 113 ? 222.232 206.996 222.077 1.00 66.15  ? 119 GLU J CA    1 
ATOM   872  C C     . GLU A 1 113 ? 222.823 207.126 223.474 1.00 66.15  ? 119 GLU J C     1 
ATOM   873  O O     . GLU A 1 113 ? 224.044 207.241 223.630 1.00 66.15  ? 119 GLU J O     1 
ATOM   874  C CB    . GLU A 1 113 ? 221.708 208.339 221.578 1.00 66.15  ? 119 GLU J CB    1 
ATOM   875  C CG    . GLU A 1 113 ? 221.554 208.398 220.073 1.00 66.15  ? 119 GLU J CG    1 
ATOM   876  C CD    . GLU A 1 113 ? 220.839 209.644 219.609 1.00 66.15  ? 119 GLU J CD    1 
ATOM   877  O OE1   . GLU A 1 113 ? 220.781 210.619 220.386 1.00 66.15  ? 119 GLU J OE1   1 
ATOM   878  O OE2   . GLU A 1 113 ? 220.335 209.649 218.467 1.00 66.15  ? 119 GLU J OE2   1 
ATOM   879  N N     . LYS A 1 114 ? 221.980 207.093 224.506 1.00 62.81  ? 120 LYS J N     1 
ATOM   880  C CA    . LYS A 1 114 ? 222.487 207.144 225.869 1.00 62.81  ? 120 LYS J CA    1 
ATOM   881  C C     . LYS A 1 114 ? 223.222 205.863 226.231 1.00 62.81  ? 120 LYS J C     1 
ATOM   882  O O     . LYS A 1 114 ? 224.227 205.909 226.943 1.00 62.81  ? 120 LYS J O     1 
ATOM   883  C CB    . LYS A 1 114 ? 221.347 207.406 226.847 1.00 62.81  ? 120 LYS J CB    1 
ATOM   884  C CG    . LYS A 1 114 ? 220.951 208.860 226.961 1.00 62.81  ? 120 LYS J CG    1 
ATOM   885  C CD    . LYS A 1 114 ? 222.126 209.704 227.415 1.00 62.81  ? 120 LYS J CD    1 
ATOM   886  C CE    . LYS A 1 114 ? 222.438 209.471 228.881 1.00 62.81  ? 120 LYS J CE    1 
ATOM   887  N NZ    . LYS A 1 114 ? 221.414 210.093 229.761 1.00 62.81  ? 120 LYS J NZ    1 
ATOM   888  N N     . MET A 1 115 ? 222.736 204.710 225.767 1.00 62.19  ? 121 MET J N     1 
ATOM   889  C CA    . MET A 1 115 ? 223.488 203.474 225.954 1.00 62.19  ? 121 MET J CA    1 
ATOM   890  C C     . MET A 1 115 ? 224.901 203.615 225.409 1.00 62.19  ? 121 MET J C     1 
ATOM   891  O O     . MET A 1 115 ? 225.885 203.314 226.098 1.00 62.19  ? 121 MET J O     1 
ATOM   892  C CB    . MET A 1 115 ? 222.771 202.313 225.269 1.00 62.19  ? 121 MET J CB    1 
ATOM   893  C CG    . MET A 1 115 ? 221.843 201.527 226.157 1.00 62.19  ? 121 MET J CG    1 
ATOM   894  S SD    . MET A 1 115 ? 221.158 200.111 225.284 1.00 62.19  ? 121 MET J SD    1 
ATOM   895  C CE    . MET A 1 115 ? 220.351 199.247 226.626 1.00 62.19  ? 121 MET J CE    1 
ATOM   896  N N     . THR A 1 116 ? 225.015 204.088 224.167 1.00 62.87  ? 122 THR J N     1 
ATOM   897  C CA    . THR A 1 116 ? 226.322 204.217 223.533 1.00 62.87  ? 122 THR J CA    1 
ATOM   898  C C     . THR A 1 116 ? 227.201 205.214 224.271 1.00 62.87  ? 122 THR J C     1 
ATOM   899  O O     . THR A 1 116 ? 228.383 204.947 224.518 1.00 62.87  ? 122 THR J O     1 
ATOM   900  C CB    . THR A 1 116 ? 226.149 204.632 222.074 1.00 62.87  ? 122 THR J CB    1 
ATOM   901  O OG1   . THR A 1 116 ? 225.396 203.631 221.385 1.00 62.87  ? 122 THR J OG1   1 
ATOM   902  C CG2   . THR A 1 116 ? 227.491 204.789 221.398 1.00 62.87  ? 122 THR J CG2   1 
ATOM   903  N N     . GLN A 1 117 ? 226.643 206.367 224.635 1.00 64.55  ? 123 GLN J N     1 
ATOM   904  C CA    . GLN A 1 117 ? 227.436 207.382 225.315 1.00 64.55  ? 123 GLN J CA    1 
ATOM   905  C C     . GLN A 1 117 ? 227.907 206.887 226.675 1.00 64.55  ? 123 GLN J C     1 
ATOM   906  O O     . GLN A 1 117 ? 229.079 207.044 227.028 1.00 64.55  ? 123 GLN J O     1 
ATOM   907  C CB    . GLN A 1 117 ? 226.628 208.668 225.455 1.00 64.55  ? 123 GLN J CB    1 
ATOM   908  C CG    . GLN A 1 117 ? 227.159 209.614 226.503 1.00 64.55  ? 123 GLN J CG    1 
ATOM   909  C CD    . GLN A 1 117 ? 226.161 210.688 226.856 1.00 64.55  ? 123 GLN J CD    1 
ATOM   910  O OE1   . GLN A 1 117 ? 225.714 211.441 225.993 1.00 64.55  ? 123 GLN J OE1   1 
ATOM   911  N NE2   . GLN A 1 117 ? 225.799 210.764 228.130 1.00 64.55  ? 123 GLN J NE2   1 
ATOM   912  N N     . ILE A 1 118 ? 227.009 206.279 227.453 1.00 61.82  ? 124 ILE J N     1 
ATOM   913  C CA    . ILE A 1 118 ? 227.388 205.753 228.761 1.00 61.82  ? 124 ILE J CA    1 
ATOM   914  C C     . ILE A 1 118 ? 228.498 204.727 228.613 1.00 61.82  ? 124 ILE J C     1 
ATOM   915  O O     . ILE A 1 118 ? 229.528 204.808 229.290 1.00 61.82  ? 124 ILE J O     1 
ATOM   916  C CB    . ILE A 1 118 ? 226.166 205.158 229.482 1.00 61.82  ? 124 ILE J CB    1 
ATOM   917  C CG1   . ILE A 1 118 ? 225.248 206.271 229.978 1.00 61.82  ? 124 ILE J CG1   1 
ATOM   918  C CG2   . ILE A 1 118 ? 226.605 204.288 230.643 1.00 61.82  ? 124 ILE J CG2   1 
ATOM   919  C CD1   . ILE A 1 118 ? 225.900 207.185 230.974 1.00 61.82  ? 124 ILE J CD1   1 
ATOM   920  N N     . MET A 1 119 ? 228.317 203.755 227.715 1.00 62.62  ? 125 MET J N     1 
ATOM   921  C CA    . MET A 1 119 ? 229.352 202.750 227.503 1.00 62.62  ? 125 MET J CA    1 
ATOM   922  C C     . MET A 1 119 ? 230.690 203.402 227.176 1.00 62.62  ? 125 MET J C     1 
ATOM   923  O O     . MET A 1 119 ? 231.656 203.284 227.937 1.00 62.62  ? 125 MET J O     1 
ATOM   924  C CB    . MET A 1 119 ? 228.928 201.792 226.393 1.00 62.62  ? 125 MET J CB    1 
ATOM   925  C CG    . MET A 1 119 ? 227.916 200.758 226.835 1.00 62.62  ? 125 MET J CG    1 
ATOM   926  S SD    . MET A 1 119 ? 228.707 199.316 227.561 1.00 62.62  ? 125 MET J SD    1 
ATOM   927  C CE    . MET A 1 119 ? 227.475 198.827 228.758 1.00 62.62  ? 125 MET J CE    1 
ATOM   928  N N     . PHE A 1 120 ? 230.743 204.154 226.075 1.00 61.65  ? 126 PHE J N     1 
ATOM   929  C CA    . PHE A 1 120 ? 232.013 204.680 225.592 1.00 61.65  ? 126 PHE J CA    1 
ATOM   930  C C     . PHE A 1 120 ? 232.624 205.729 226.510 1.00 61.65  ? 126 PHE J C     1 
ATOM   931  O O     . PHE A 1 120 ? 233.817 206.013 226.383 1.00 61.65  ? 126 PHE J O     1 
ATOM   932  C CB    . PHE A 1 120 ? 231.839 205.273 224.197 1.00 61.65  ? 126 PHE J CB    1 
ATOM   933  C CG    . PHE A 1 120 ? 231.863 204.256 223.103 1.00 61.65  ? 126 PHE J CG    1 
ATOM   934  C CD1   . PHE A 1 120 ? 232.818 203.263 223.087 1.00 61.65  ? 126 PHE J CD1   1 
ATOM   935  C CD2   . PHE A 1 120 ? 230.927 204.289 222.093 1.00 61.65  ? 126 PHE J CD2   1 
ATOM   936  C CE1   . PHE A 1 120 ? 232.837 202.328 222.084 1.00 61.65  ? 126 PHE J CE1   1 
ATOM   937  C CE2   . PHE A 1 120 ? 230.945 203.354 221.090 1.00 61.65  ? 126 PHE J CE2   1 
ATOM   938  C CZ    . PHE A 1 120 ? 231.900 202.375 221.087 1.00 61.65  ? 126 PHE J CZ    1 
ATOM   939  N N     . GLU A 1 121 ? 231.855 206.315 227.425 1.00 65.93  ? 127 GLU J N     1 
ATOM   940  C CA    . GLU A 1 121 ? 232.413 207.366 228.269 1.00 65.93  ? 127 GLU J CA    1 
ATOM   941  C C     . GLU A 1 121 ? 232.779 206.858 229.661 1.00 65.93  ? 127 GLU J C     1 
ATOM   942  O O     . GLU A 1 121 ? 233.887 207.109 230.144 1.00 65.93  ? 127 GLU J O     1 
ATOM   943  C CB    . GLU A 1 121 ? 231.430 208.537 228.363 1.00 65.93  ? 127 GLU J CB    1 
ATOM   944  C CG    . GLU A 1 121 ? 231.250 209.297 227.059 1.00 65.93  ? 127 GLU J CG    1 
ATOM   945  C CD    . GLU A 1 121 ? 232.356 210.297 226.794 1.00 65.93  ? 127 GLU J CD    1 
ATOM   946  O OE1   . GLU A 1 121 ? 233.376 210.275 227.514 1.00 65.93  ? 127 GLU J OE1   1 
ATOM   947  O OE2   . GLU A 1 121 ? 232.205 211.111 225.860 1.00 65.93  ? 127 GLU J OE2   1 
ATOM   948  N N     . THR A 1 122 ? 231.864 206.155 230.323 1.00 62.80  ? 128 THR J N     1 
ATOM   949  C CA    . THR A 1 122 ? 232.088 205.722 231.691 1.00 62.80  ? 128 THR J CA    1 
ATOM   950  C C     . THR A 1 122 ? 232.585 204.289 231.794 1.00 62.80  ? 128 THR J C     1 
ATOM   951  O O     . THR A 1 122 ? 232.862 203.830 232.904 1.00 62.80  ? 128 THR J O     1 
ATOM   952  C CB    . THR A 1 122 ? 230.803 205.862 232.506 1.00 62.80  ? 128 THR J CB    1 
ATOM   953  O OG1   . THR A 1 122 ? 229.817 204.960 231.995 1.00 62.80  ? 128 THR J OG1   1 
ATOM   954  C CG2   . THR A 1 122 ? 230.271 207.279 232.406 1.00 62.80  ? 128 THR J CG2   1 
ATOM   955  N N     . PHE A 1 123 ? 232.702 203.565 230.682 1.00 61.42  ? 129 PHE J N     1 
ATOM   956  C CA    . PHE A 1 123 ? 233.273 202.229 230.716 1.00 61.42  ? 129 PHE J CA    1 
ATOM   957  C C     . PHE A 1 123 ? 234.427 202.037 229.752 1.00 61.42  ? 129 PHE J C     1 
ATOM   958  O O     . PHE A 1 123 ? 235.181 201.072 229.916 1.00 61.42  ? 129 PHE J O     1 
ATOM   959  C CB    . PHE A 1 123 ? 232.197 201.172 230.426 1.00 61.42  ? 129 PHE J CB    1 
ATOM   960  C CG    . PHE A 1 123 ? 231.180 201.031 231.520 1.00 61.42  ? 129 PHE J CG    1 
ATOM   961  C CD1   . PHE A 1 123 ? 231.435 200.245 232.625 1.00 61.42  ? 129 PHE J CD1   1 
ATOM   962  C CD2   . PHE A 1 123 ? 229.968 201.687 231.446 1.00 61.42  ? 129 PHE J CD2   1 
ATOM   963  C CE1   . PHE A 1 123 ? 230.503 200.119 233.634 1.00 61.42  ? 129 PHE J CE1   1 
ATOM   964  C CE2   . PHE A 1 123 ? 229.034 201.560 232.452 1.00 61.42  ? 129 PHE J CE2   1 
ATOM   965  C CZ    . PHE A 1 123 ? 229.304 200.776 233.545 1.00 61.42  ? 129 PHE J CZ    1 
ATOM   966  N N     . ASN A 1 124 ? 234.596 202.919 228.766 1.00 63.91  ? 130 ASN J N     1 
ATOM   967  C CA    . ASN A 1 124 ? 235.730 202.882 227.845 1.00 63.91  ? 130 ASN J CA    1 
ATOM   968  C C     . ASN A 1 124 ? 235.856 201.527 227.160 1.00 63.91  ? 130 ASN J C     1 
ATOM   969  O O     . ASN A 1 124 ? 236.945 200.962 227.062 1.00 63.91  ? 130 ASN J O     1 
ATOM   970  C CB    . ASN A 1 124 ? 237.033 203.247 228.556 1.00 63.91  ? 130 ASN J CB    1 
ATOM   971  C CG    . ASN A 1 124 ? 237.130 204.721 228.873 1.00 63.91  ? 130 ASN J CG    1 
ATOM   972  O OD1   . ASN A 1 124 ? 237.892 205.454 228.243 1.00 63.91  ? 130 ASN J OD1   1 
ATOM   973  N ND2   . ASN A 1 124 ? 236.361 205.165 229.856 1.00 63.91  ? 130 ASN J ND2   1 
ATOM   974  N N     . VAL A 1 125 ? 234.734 200.992 226.694 1.00 60.43  ? 131 VAL J N     1 
ATOM   975  C CA    . VAL A 1 125 ? 234.757 199.746 225.936 1.00 60.43  ? 131 VAL J CA    1 
ATOM   976  C C     . VAL A 1 125 ? 235.415 200.031 224.593 1.00 60.43  ? 131 VAL J C     1 
ATOM   977  O O     . VAL A 1 125 ? 235.291 201.148 224.071 1.00 60.43  ? 131 VAL J O     1 
ATOM   978  C CB    . VAL A 1 125 ? 233.346 199.164 225.766 1.00 60.43  ? 131 VAL J CB    1 
ATOM   979  C CG1   . VAL A 1 125 ? 232.775 198.773 227.111 1.00 60.43  ? 131 VAL J CG1   1 
ATOM   980  C CG2   . VAL A 1 125 ? 232.441 200.167 225.091 1.00 60.43  ? 131 VAL J CG2   1 
ATOM   981  N N     . PRO A 1 126 ? 236.141 199.077 224.008 1.00 62.50  ? 132 PRO J N     1 
ATOM   982  C CA    . PRO A 1 126 ? 236.722 199.331 222.684 1.00 62.50  ? 132 PRO J CA    1 
ATOM   983  C C     . PRO A 1 126 ? 235.689 199.337 221.574 1.00 62.50  ? 132 PRO J C     1 
ATOM   984  O O     . PRO A 1 126 ? 235.883 200.025 220.565 1.00 62.50  ? 132 PRO J O     1 
ATOM   985  C CB    . PRO A 1 126 ? 237.724 198.184 222.519 1.00 62.50  ? 132 PRO J CB    1 
ATOM   986  C CG    . PRO A 1 126 ? 237.180 197.103 223.362 1.00 62.50  ? 132 PRO J CG    1 
ATOM   987  C CD    . PRO A 1 126 ? 236.552 197.772 224.546 1.00 62.50  ? 132 PRO J CD    1 
ATOM   988  N N     . ALA A 1 127 ? 234.595 198.599 221.733 1.00 60.66  ? 133 ALA J N     1 
ATOM   989  C CA    . ALA A 1 127 ? 233.567 198.519 220.708 1.00 60.66  ? 133 ALA J CA    1 
ATOM   990  C C     . ALA A 1 127 ? 232.260 198.109 221.363 1.00 60.66  ? 133 ALA J C     1 
ATOM   991  O O     . ALA A 1 127 ? 232.244 197.589 222.480 1.00 60.66  ? 133 ALA J O     1 
ATOM   992  C CB    . ALA A 1 127 ? 233.956 197.531 219.608 1.00 60.66  ? 133 ALA J CB    1 
ATOM   993  N N     . MET A 1 128 ? 231.161 198.346 220.654 1.00 60.32  ? 134 MET J N     1 
ATOM   994  C CA    . MET A 1 128 ? 229.850 197.945 221.142 1.00 60.32  ? 134 MET J CA    1 
ATOM   995  C C     . MET A 1 128 ? 228.904 197.798 219.961 1.00 60.32  ? 134 MET J C     1 
ATOM   996  O O     . MET A 1 128 ? 229.238 198.131 218.823 1.00 60.32  ? 134 MET J O     1 
ATOM   997  C CB    . MET A 1 128 ? 229.290 198.947 222.148 1.00 60.32  ? 134 MET J CB    1 
ATOM   998  C CG    . MET A 1 128 ? 228.963 200.283 221.538 1.00 60.32  ? 134 MET J CG    1 
ATOM   999  S SD    . MET A 1 128 ? 228.182 201.385 222.716 1.00 60.32  ? 134 MET J SD    1 
ATOM   1000 C CE    . MET A 1 128 ? 226.564 200.638 222.831 1.00 60.32  ? 134 MET J CE    1 
ATOM   1001 N N     . TYR A 1 129 ? 227.706 197.303 220.255 1.00 57.98  ? 135 TYR J N     1 
ATOM   1002 C CA    . TYR A 1 129 ? 226.686 197.070 219.245 1.00 57.98  ? 135 TYR J CA    1 
ATOM   1003 C C     . TYR A 1 129 ? 225.363 196.845 219.959 1.00 57.98  ? 135 TYR J C     1 
ATOM   1004 O O     . TYR A 1 129 ? 225.329 196.287 221.057 1.00 57.98  ? 135 TYR J O     1 
ATOM   1005 C CB    . TYR A 1 129 ? 227.046 195.870 218.365 1.00 57.98  ? 135 TYR J CB    1 
ATOM   1006 C CG    . TYR A 1 129 ? 226.249 195.756 217.088 1.00 57.98  ? 135 TYR J CG    1 
ATOM   1007 C CD1   . TYR A 1 129 ? 226.601 196.480 215.961 1.00 57.98  ? 135 TYR J CD1   1 
ATOM   1008 C CD2   . TYR A 1 129 ? 225.155 194.911 217.005 1.00 57.98  ? 135 TYR J CD2   1 
ATOM   1009 C CE1   . TYR A 1 129 ? 225.881 196.371 214.794 1.00 57.98  ? 135 TYR J CE1   1 
ATOM   1010 C CE2   . TYR A 1 129 ? 224.430 194.798 215.841 1.00 57.98  ? 135 TYR J CE2   1 
ATOM   1011 C CZ    . TYR A 1 129 ? 224.797 195.529 214.740 1.00 57.98  ? 135 TYR J CZ    1 
ATOM   1012 O OH    . TYR A 1 129 ? 224.073 195.415 213.579 1.00 57.98  ? 135 TYR J OH    1 
ATOM   1013 N N     . VAL A 1 130 ? 224.279 197.292 219.337 1.00 57.85  ? 136 VAL J N     1 
ATOM   1014 C CA    . VAL A 1 130 ? 222.950 197.230 219.935 1.00 57.85  ? 136 VAL J CA    1 
ATOM   1015 C C     . VAL A 1 130 ? 222.044 196.506 218.951 1.00 57.85  ? 136 VAL J C     1 
ATOM   1016 O O     . VAL A 1 130 ? 221.545 197.106 217.994 1.00 57.85  ? 136 VAL J O     1 
ATOM   1017 C CB    . VAL A 1 130 ? 222.401 198.618 220.275 1.00 57.85  ? 136 VAL J CB    1 
ATOM   1018 C CG1   . VAL A 1 130 ? 221.037 198.496 220.920 1.00 57.85  ? 136 VAL J CG1   1 
ATOM   1019 C CG2   . VAL A 1 130 ? 223.356 199.359 221.192 1.00 57.85  ? 136 VAL J CG2   1 
ATOM   1020 N N     . ALA A 1 131 ? 221.819 195.217 219.183 1.00 55.83  ? 137 ALA J N     1 
ATOM   1021 C CA    . ALA A 1 131 ? 221.007 194.401 218.298 1.00 55.83  ? 137 ALA J CA    1 
ATOM   1022 C C     . ALA A 1 131 ? 219.541 194.443 218.726 1.00 55.83  ? 137 ALA J C     1 
ATOM   1023 O O     . ALA A 1 131 ? 219.160 195.131 219.673 1.00 55.83  ? 137 ALA J O     1 
ATOM   1024 C CB    . ALA A 1 131 ? 221.535 192.969 218.273 1.00 55.83  ? 137 ALA J CB    1 
ATOM   1025 N N     . ILE A 1 132 ? 218.705 193.699 218.009 1.00 55.95  ? 138 ILE J N     1 
ATOM   1026 C CA    . ILE A 1 132 ? 217.287 193.564 218.318 1.00 55.95  ? 138 ILE J CA    1 
ATOM   1027 C C     . ILE A 1 132 ? 217.057 192.167 218.870 1.00 55.95  ? 138 ILE J C     1 
ATOM   1028 O O     . ILE A 1 132 ? 217.599 191.189 218.345 1.00 55.95  ? 138 ILE J O     1 
ATOM   1029 C CB    . ILE A 1 132 ? 216.411 193.819 217.076 1.00 55.95  ? 138 ILE J CB    1 
ATOM   1030 C CG1   . ILE A 1 132 ? 216.687 195.209 216.503 1.00 55.95  ? 138 ILE J CG1   1 
ATOM   1031 C CG2   . ILE A 1 132 ? 214.940 193.669 217.414 1.00 55.95  ? 138 ILE J CG2   1 
ATOM   1032 C CD1   . ILE A 1 132 ? 216.151 196.338 217.343 1.00 55.95  ? 138 ILE J CD1   1 
ATOM   1033 N N     . GLN A 1 133 ? 216.249 192.072 219.929 1.00 57.00  ? 139 GLN J N     1 
ATOM   1034 C CA    . GLN A 1 133 ? 216.081 190.800 220.626 1.00 57.00  ? 139 GLN J CA    1 
ATOM   1035 C C     . GLN A 1 133 ? 215.488 189.727 219.723 1.00 57.00  ? 139 GLN J C     1 
ATOM   1036 O O     . GLN A 1 133 ? 215.798 188.539 219.878 1.00 57.00  ? 139 GLN J O     1 
ATOM   1037 C CB    . GLN A 1 133 ? 215.202 190.995 221.858 1.00 57.00  ? 139 GLN J CB    1 
ATOM   1038 C CG    . GLN A 1 133 ? 215.686 192.085 222.785 1.00 57.00  ? 139 GLN J CG    1 
ATOM   1039 C CD    . GLN A 1 133 ? 214.820 192.238 224.009 1.00 57.00  ? 139 GLN J CD    1 
ATOM   1040 O OE1   . GLN A 1 133 ? 213.686 191.766 224.044 1.00 57.00  ? 139 GLN J OE1   1 
ATOM   1041 N NE2   . GLN A 1 133 ? 215.348 192.906 225.026 1.00 57.00  ? 139 GLN J NE2   1 
ATOM   1042 N N     . ALA A 1 134 ? 214.653 190.123 218.764 1.00 53.77  ? 140 ALA J N     1 
ATOM   1043 C CA    . ALA A 1 134 ? 213.968 189.149 217.924 1.00 53.77  ? 140 ALA J CA    1 
ATOM   1044 C C     . ALA A 1 134 ? 214.921 188.482 216.939 1.00 53.77  ? 140 ALA J C     1 
ATOM   1045 O O     . ALA A 1 134 ? 214.858 187.263 216.733 1.00 53.77  ? 140 ALA J O     1 
ATOM   1046 C CB    . ALA A 1 134 ? 212.826 189.835 217.186 1.00 53.77  ? 140 ALA J CB    1 
ATOM   1047 N N     . VAL A 1 135 ? 215.801 189.262 216.312 1.00 51.19  ? 141 VAL J N     1 
ATOM   1048 C CA    . VAL A 1 135 ? 216.771 188.685 215.387 1.00 51.19  ? 141 VAL J CA    1 
ATOM   1049 C C     . VAL A 1 135 ? 217.672 187.696 216.113 1.00 51.19  ? 141 VAL J C     1 
ATOM   1050 O O     . VAL A 1 135 ? 218.010 186.631 215.582 1.00 51.19  ? 141 VAL J O     1 
ATOM   1051 C CB    . VAL A 1 135 ? 217.582 189.802 214.707 1.00 51.19  ? 141 VAL J CB    1 
ATOM   1052 C CG1   . VAL A 1 135 ? 218.592 189.214 213.753 1.00 51.19  ? 141 VAL J CG1   1 
ATOM   1053 C CG2   . VAL A 1 135 ? 216.655 190.757 213.981 1.00 51.19  ? 141 VAL J CG2   1 
ATOM   1054 N N     . LEU A 1 136 ? 218.063 188.023 217.344 1.00 50.23  ? 142 LEU J N     1 
ATOM   1055 C CA    . LEU A 1 136 ? 218.889 187.106 218.119 1.00 50.23  ? 142 LEU J CA    1 
ATOM   1056 C C     . LEU A 1 136 ? 218.115 185.848 218.489 1.00 50.23  ? 142 LEU J C     1 
ATOM   1057 O O     . LEU A 1 136 ? 218.669 184.742 218.469 1.00 50.23  ? 142 LEU J O     1 
ATOM   1058 C CB    . LEU A 1 136 ? 219.415 187.809 219.367 1.00 50.23  ? 142 LEU J CB    1 
ATOM   1059 C CG    . LEU A 1 136 ? 220.060 189.173 219.137 1.00 50.23  ? 142 LEU J CG    1 
ATOM   1060 C CD1   . LEU A 1 136 ? 220.724 189.664 220.401 1.00 50.23  ? 142 LEU J CD1   1 
ATOM   1061 C CD2   . LEU A 1 136 ? 221.065 189.107 218.010 1.00 50.23  ? 142 LEU J CD2   1 
ATOM   1062 N N     . SER A 1 137 ? 216.835 185.992 218.835 1.00 50.33  ? 143 SER J N     1 
ATOM   1063 C CA    . SER A 1 137 ? 216.023 184.809 219.095 1.00 50.33  ? 143 SER J CA    1 
ATOM   1064 C C     . SER A 1 137 ? 215.961 183.911 217.869 1.00 50.33  ? 143 SER J C     1 
ATOM   1065 O O     . SER A 1 137 ? 215.969 182.680 217.986 1.00 50.33  ? 143 SER J O     1 
ATOM   1066 C CB    . SER A 1 137 ? 214.620 185.218 219.524 1.00 50.33  ? 143 SER J CB    1 
ATOM   1067 O OG    . SER A 1 137 ? 213.853 184.075 219.839 1.00 50.33  ? 143 SER J OG    1 
ATOM   1068 N N     . LEU A 1 138 ? 215.916 184.511 216.682 1.00 50.22  ? 144 LEU J N     1 
ATOM   1069 C CA    . LEU A 1 138 ? 215.895 183.711 215.463 1.00 50.22  ? 144 LEU J CA    1 
ATOM   1070 C C     . LEU A 1 138 ? 217.227 183.009 215.242 1.00 50.22  ? 144 LEU J C     1 
ATOM   1071 O O     . LEU A 1 138 ? 217.256 181.831 214.872 1.00 50.22  ? 144 LEU J O     1 
ATOM   1072 C CB    . LEU A 1 138 ? 215.544 184.582 214.264 1.00 50.22  ? 144 LEU J CB    1 
ATOM   1073 C CG    . LEU A 1 138 ? 214.754 183.847 213.190 1.00 50.22  ? 144 LEU J CG    1 
ATOM   1074 C CD1   . LEU A 1 138 ? 213.447 183.343 213.756 1.00 50.22  ? 144 LEU J CD1   1 
ATOM   1075 C CD2   . LEU A 1 138 ? 214.514 184.761 212.018 1.00 50.22  ? 144 LEU J CD2   1 
ATOM   1076 N N     . TYR A 1 139 ? 218.338 183.723 215.442 1.00 50.90  ? 145 TYR J N     1 
ATOM   1077 C CA    . TYR A 1 139 ? 219.653 183.085 215.417 1.00 50.90  ? 145 TYR J CA    1 
ATOM   1078 C C     . TYR A 1 139 ? 219.677 181.862 216.320 1.00 50.90  ? 145 TYR J C     1 
ATOM   1079 O O     . TYR A 1 139 ? 220.165 180.795 215.936 1.00 50.90  ? 145 TYR J O     1 
ATOM   1080 C CB    . TYR A 1 139 ? 220.740 184.064 215.862 1.00 50.90  ? 145 TYR J CB    1 
ATOM   1081 C CG    . TYR A 1 139 ? 221.278 184.981 214.794 1.00 50.90  ? 145 TYR J CG    1 
ATOM   1082 C CD1   . TYR A 1 139 ? 220.920 186.316 214.758 1.00 50.90  ? 145 TYR J CD1   1 
ATOM   1083 C CD2   . TYR A 1 139 ? 222.164 184.516 213.838 1.00 50.90  ? 145 TYR J CD2   1 
ATOM   1084 C CE1   . TYR A 1 139 ? 221.415 187.157 213.796 1.00 50.90  ? 145 TYR J CE1   1 
ATOM   1085 C CE2   . TYR A 1 139 ? 222.664 185.353 212.870 1.00 50.90  ? 145 TYR J CE2   1 
ATOM   1086 C CZ    . TYR A 1 139 ? 222.285 186.672 212.855 1.00 50.90  ? 145 TYR J CZ    1 
ATOM   1087 O OH    . TYR A 1 139 ? 222.777 187.519 211.892 1.00 50.90  ? 145 TYR J OH    1 
ATOM   1088 N N     . ALA A 1 140 ? 219.148 182.006 217.535 1.00 50.62  ? 146 ALA J N     1 
ATOM   1089 C CA    . ALA A 1 140 ? 219.208 180.919 218.503 1.00 50.62  ? 146 ALA J CA    1 
ATOM   1090 C C     . ALA A 1 140 ? 218.282 179.771 218.136 1.00 50.62  ? 146 ALA J C     1 
ATOM   1091 O O     . ALA A 1 140 ? 218.562 178.620 218.483 1.00 50.62  ? 146 ALA J O     1 
ATOM   1092 C CB    . ALA A 1 140 ? 218.868 181.437 219.896 1.00 50.62  ? 146 ALA J CB    1 
ATOM   1093 N N     . SER A 1 141 ? 217.176 180.053 217.448 1.00 50.83  ? 147 SER J N     1 
ATOM   1094 C CA    . SER A 1 141 ? 216.247 178.984 217.102 1.00 50.83  ? 147 SER J CA    1 
ATOM   1095 C C     . SER A 1 141 ? 216.751 178.097 215.973 1.00 50.83  ? 147 SER J C     1 
ATOM   1096 O O     . SER A 1 141 ? 216.144 177.054 215.715 1.00 50.83  ? 147 SER J O     1 
ATOM   1097 C CB    . SER A 1 141 ? 214.891 179.562 216.716 1.00 50.83  ? 147 SER J CB    1 
ATOM   1098 O OG    . SER A 1 141 ? 214.007 178.529 216.325 1.00 50.83  ? 147 SER J OG    1 
ATOM   1099 N N     . GLY A 1 142 ? 217.828 178.480 215.296 1.00 53.14  ? 148 GLY J N     1 
ATOM   1100 C CA    . GLY A 1 142 ? 218.379 177.663 214.236 1.00 53.14  ? 148 GLY J CA    1 
ATOM   1101 C C     . GLY A 1 142 ? 217.564 177.689 212.962 1.00 53.14  ? 148 GLY J C     1 
ATOM   1102 O O     . GLY A 1 142 ? 217.239 176.635 212.410 1.00 53.14  ? 148 GLY J O     1 
ATOM   1103 N N     . ARG A 1 143 ? 217.234 178.885 212.483 1.00 50.89  ? 149 ARG J N     1 
ATOM   1104 C CA    . ARG A 1 143 ? 216.478 179.041 211.247 1.00 50.89  ? 149 ARG J CA    1 
ATOM   1105 C C     . ARG A 1 143 ? 216.582 180.492 210.802 1.00 50.89  ? 149 ARG J C     1 
ATOM   1106 O O     . ARG A 1 143 ? 217.012 181.365 211.557 1.00 50.89  ? 149 ARG J O     1 
ATOM   1107 C CB    . ARG A 1 143 ? 215.015 178.623 211.420 1.00 50.89  ? 149 ARG J CB    1 
ATOM   1108 C CG    . ARG A 1 143 ? 214.296 179.346 212.533 1.00 50.89  ? 149 ARG J CG    1 
ATOM   1109 C CD    . ARG A 1 143 ? 212.806 179.079 212.500 1.00 50.89  ? 149 ARG J CD    1 
ATOM   1110 N NE    . ARG A 1 143 ? 212.490 177.661 212.394 1.00 50.89  ? 149 ARG J NE    1 
ATOM   1111 C CZ    . ARG A 1 143 ? 212.627 176.788 213.383 1.00 50.89  ? 149 ARG J CZ    1 
ATOM   1112 N NH1   . ARG A 1 143 ? 213.080 177.182 214.562 1.00 50.89  ? 149 ARG J NH1   1 
ATOM   1113 N NH2   . ARG A 1 143 ? 212.310 175.517 213.195 1.00 50.89  ? 149 ARG J NH2   1 
ATOM   1114 N N     . THR A 1 144 ? 216.182 180.736 209.555 1.00 51.57  ? 150 THR J N     1 
ATOM   1115 C CA    . THR A 1 144 ? 216.277 182.057 208.949 1.00 51.57  ? 150 THR J CA    1 
ATOM   1116 C C     . THR A 1 144 ? 214.927 182.599 208.505 1.00 51.57  ? 150 THR J C     1 
ATOM   1117 O O     . THR A 1 144 ? 214.865 183.708 207.964 1.00 51.57  ? 150 THR J O     1 
ATOM   1118 C CB    . THR A 1 144 ? 217.233 182.028 207.755 1.00 51.57  ? 150 THR J CB    1 
ATOM   1119 O OG1   . THR A 1 144 ? 216.864 180.959 206.877 1.00 51.57  ? 150 THR J OG1   1 
ATOM   1120 C CG2   . THR A 1 144 ? 218.657 181.819 208.222 1.00 51.57  ? 150 THR J CG2   1 
ATOM   1121 N N     . THR A 1 145 ? 213.848 181.853 208.718 1.00 51.70  ? 151 THR J N     1 
ATOM   1122 C CA    . THR A 1 145 ? 212.516 182.275 208.306 1.00 51.70  ? 151 THR J CA    1 
ATOM   1123 C C     . THR A 1 145 ? 211.544 181.974 209.431 1.00 51.70  ? 151 THR J C     1 
ATOM   1124 O O     . THR A 1 145 ? 211.376 180.812 209.810 1.00 51.70  ? 151 THR J O     1 
ATOM   1125 C CB    . THR A 1 145 ? 212.075 181.561 207.028 1.00 51.70  ? 151 THR J CB    1 
ATOM   1126 O OG1   . THR A 1 145 ? 212.965 181.896 205.958 1.00 51.70  ? 151 THR J OG1   1 
ATOM   1127 C CG2   . THR A 1 145 ? 210.669 181.965 206.655 1.00 51.70  ? 151 THR J CG2   1 
ATOM   1128 N N     . GLY A 1 146 ? 210.904 183.010 209.956 1.00 49.33  ? 152 GLY J N     1 
ATOM   1129 C CA    . GLY A 1 146 ? 209.920 182.822 210.999 1.00 49.33  ? 152 GLY J CA    1 
ATOM   1130 C C     . GLY A 1 146 ? 209.432 184.128 211.578 1.00 49.33  ? 152 GLY J C     1 
ATOM   1131 O O     . GLY A 1 146 ? 210.078 185.164 211.414 1.00 49.33  ? 152 GLY J O     1 
ATOM   1132 N N     . ILE A 1 147 ? 208.287 184.097 212.247 1.00 48.76  ? 153 ILE J N     1 
ATOM   1133 C CA    . ILE A 1 147 ? 207.762 185.251 212.960 1.00 48.76  ? 153 ILE J CA    1 
ATOM   1134 C C     . ILE A 1 147 ? 207.871 184.963 214.448 1.00 48.76  ? 153 ILE J C     1 
ATOM   1135 O O     . ILE A 1 147 ? 207.229 184.043 214.966 1.00 48.76  ? 153 ILE J O     1 
ATOM   1136 C CB    . ILE A 1 147 ? 206.324 185.588 212.536 1.00 48.76  ? 153 ILE J CB    1 
ATOM   1137 C CG1   . ILE A 1 147 ? 205.830 186.822 213.287 1.00 48.76  ? 153 ILE J CG1   1 
ATOM   1138 C CG2   . ILE A 1 147 ? 205.390 184.396 212.673 1.00 48.76  ? 153 ILE J CG2   1 
ATOM   1139 C CD1   . ILE A 1 147 ? 204.590 187.409 212.709 1.00 48.76  ? 153 ILE J CD1   1 
ATOM   1140 N N     . VAL A 1 148 ? 208.713 185.725 215.128 1.00 48.28  ? 154 VAL J N     1 
ATOM   1141 C CA    . VAL A 1 148 ? 209.054 185.470 216.518 1.00 48.28  ? 154 VAL J CA    1 
ATOM   1142 C C     . VAL A 1 148 ? 208.154 186.302 217.420 1.00 48.28  ? 154 VAL J C     1 
ATOM   1143 O O     . VAL A 1 148 ? 207.967 187.504 217.198 1.00 48.28  ? 154 VAL J O     1 
ATOM   1144 C CB    . VAL A 1 148 ? 210.543 185.754 216.777 1.00 48.28  ? 154 VAL J CB    1 
ATOM   1145 C CG1   . VAL A 1 148 ? 210.886 187.145 216.351 1.00 48.28  ? 154 VAL J CG1   1 
ATOM   1146 C CG2   . VAL A 1 148 ? 210.874 185.559 218.239 1.00 48.28  ? 154 VAL J CG2   1 
ATOM   1147 N N     . LEU A 1 149 ? 207.566 185.650 218.415 1.00 50.59  ? 155 LEU J N     1 
ATOM   1148 C CA    . LEU A 1 149 ? 206.765 186.293 219.449 1.00 50.59  ? 155 LEU J CA    1 
ATOM   1149 C C     . LEU A 1 149 ? 207.624 186.322 220.710 1.00 50.59  ? 155 LEU J C     1 
ATOM   1150 O O     . LEU A 1 149 ? 207.680 185.350 221.462 1.00 50.59  ? 155 LEU J O     1 
ATOM   1151 C CB    . LEU A 1 149 ? 205.456 185.546 219.665 1.00 50.59  ? 155 LEU J CB    1 
ATOM   1152 C CG    . LEU A 1 149 ? 204.620 185.914 220.890 1.00 50.59  ? 155 LEU J CG    1 
ATOM   1153 C CD1   . LEU A 1 149 ? 204.300 187.387 220.889 1.00 50.59  ? 155 LEU J CD1   1 
ATOM   1154 C CD2   . LEU A 1 149 ? 203.349 185.095 220.922 1.00 50.59  ? 155 LEU J CD2   1 
ATOM   1155 N N     . ASP A 1 150 ? 208.307 187.437 220.930 1.00 53.46  ? 156 ASP J N     1 
ATOM   1156 C CA    . ASP A 1 150 ? 209.216 187.581 222.058 1.00 53.46  ? 156 ASP J CA    1 
ATOM   1157 C C     . ASP A 1 150 ? 208.538 188.411 223.137 1.00 53.46  ? 156 ASP J C     1 
ATOM   1158 O O     . ASP A 1 150 ? 208.340 189.617 222.965 1.00 53.46  ? 156 ASP J O     1 
ATOM   1159 C CB    . ASP A 1 150 ? 210.526 188.231 221.618 1.00 53.46  ? 156 ASP J CB    1 
ATOM   1160 C CG    . ASP A 1 150 ? 211.564 188.252 222.720 1.00 53.46  ? 156 ASP J CG    1 
ATOM   1161 O OD1   . ASP A 1 150 ? 212.181 187.197 222.979 1.00 53.46  ? 156 ASP J OD1   1 
ATOM   1162 O OD2   . ASP A 1 150 ? 211.766 189.324 223.328 1.00 53.46  ? 156 ASP J OD2   1 
ATOM   1163 N N     . SER A 1 151 ? 208.195 187.768 224.249 1.00 51.41  ? 157 SER J N     1 
ATOM   1164 C CA    . SER A 1 151 ? 207.459 188.406 225.334 1.00 51.41  ? 157 SER J CA    1 
ATOM   1165 C C     . SER A 1 151 ? 208.286 188.293 226.604 1.00 51.41  ? 157 SER J C     1 
ATOM   1166 O O     . SER A 1 151 ? 208.461 187.195 227.138 1.00 51.41  ? 157 SER J O     1 
ATOM   1167 C CB    . SER A 1 151 ? 206.088 187.761 225.517 1.00 51.41  ? 157 SER J CB    1 
ATOM   1168 O OG    . SER A 1 151 ? 205.389 188.358 226.591 1.00 51.41  ? 157 SER J OG    1 
ATOM   1169 N N     . GLY A 1 152 ? 208.792 189.420 227.087 1.00 52.71  ? 158 GLY J N     1 
ATOM   1170 C CA    . GLY A 1 152 ? 209.616 189.410 228.276 1.00 52.71  ? 158 GLY J CA    1 
ATOM   1171 C C     . GLY A 1 152 ? 208.885 189.873 229.515 1.00 52.71  ? 158 GLY J C     1 
ATOM   1172 O O     . GLY A 1 152 ? 207.828 189.340 229.860 1.00 52.71  ? 158 GLY J O     1 
ATOM   1173 N N     . ASP A 1 153 ? 209.447 190.867 230.198 1.00 57.32  ? 159 ASP J N     1 
ATOM   1174 C CA    . ASP A 1 153 ? 208.848 191.422 231.399 1.00 57.32  ? 159 ASP J CA    1 
ATOM   1175 C C     . ASP A 1 153 ? 208.370 192.853 231.224 1.00 57.32  ? 159 ASP J C     1 
ATOM   1176 O O     . ASP A 1 153 ? 207.693 193.374 232.116 1.00 57.32  ? 159 ASP J O     1 
ATOM   1177 C CB    . ASP A 1 153 ? 209.848 191.367 232.561 1.00 57.32  ? 159 ASP J CB    1 
ATOM   1178 C CG    . ASP A 1 153 ? 209.172 191.254 233.907 1.00 57.32  ? 159 ASP J CG    1 
ATOM   1179 O OD1   . ASP A 1 153 ? 208.371 190.318 234.091 1.00 57.32  ? 159 ASP J OD1   1 
ATOM   1180 O OD2   . ASP A 1 153 ? 209.448 192.098 234.785 1.00 57.32  ? 159 ASP J OD2   1 
ATOM   1181 N N     . GLY A 1 154 ? 208.702 193.504 230.116 1.00 58.08  ? 160 GLY J N     1 
ATOM   1182 C CA    . GLY A 1 154 ? 208.258 194.863 229.905 1.00 58.08  ? 160 GLY J CA    1 
ATOM   1183 C C     . GLY A 1 154 ? 207.488 195.087 228.622 1.00 58.08  ? 160 GLY J C     1 
ATOM   1184 O O     . GLY A 1 154 ? 206.694 196.027 228.536 1.00 58.08  ? 160 GLY J O     1 
ATOM   1185 N N     . VAL A 1 155 ? 207.700 194.238 227.618 1.00 54.01  ? 161 VAL J N     1 
ATOM   1186 C CA    . VAL A 1 155 ? 207.161 194.484 226.288 1.00 54.01  ? 161 VAL J CA    1 
ATOM   1187 C C     . VAL A 1 155 ? 206.981 193.157 225.565 1.00 54.01  ? 161 VAL J C     1 
ATOM   1188 O O     . VAL A 1 155 ? 207.749 192.213 225.760 1.00 54.01  ? 161 VAL J O     1 
ATOM   1189 C CB    . VAL A 1 155 ? 208.078 195.444 225.494 1.00 54.01  ? 161 VAL J CB    1 
ATOM   1190 C CG1   . VAL A 1 155 ? 209.435 194.821 225.272 1.00 54.01  ? 161 VAL J CG1   1 
ATOM   1191 C CG2   . VAL A 1 155 ? 207.450 195.820 224.174 1.00 54.01  ? 161 VAL J CG2   1 
ATOM   1192 N N     . THR A 1 156 ? 205.935 193.087 224.746 1.00 53.54  ? 162 THR J N     1 
ATOM   1193 C CA    . THR A 1 156 ? 205.684 191.976 223.840 1.00 53.54  ? 162 THR J CA    1 
ATOM   1194 C C     . THR A 1 156 ? 205.757 192.499 222.415 1.00 53.54  ? 162 THR J C     1 
ATOM   1195 O O     . THR A 1 156 ? 205.168 193.540 222.109 1.00 53.54  ? 162 THR J O     1 
ATOM   1196 C CB    . THR A 1 156 ? 204.311 191.357 224.101 1.00 53.54  ? 162 THR J CB    1 
ATOM   1197 O OG1   . THR A 1 156 ? 204.129 191.173 225.508 1.00 53.54  ? 162 THR J OG1   1 
ATOM   1198 C CG2   . THR A 1 156 ? 204.181 190.025 223.403 1.00 53.54  ? 162 THR J CG2   1 
ATOM   1199 N N     . HIS A 1 157 ? 206.470 191.791 221.542 1.00 53.13  ? 163 HIS J N     1 
ATOM   1200 C CA    . HIS A 1 157 ? 206.607 192.272 220.176 1.00 53.13  ? 163 HIS J CA    1 
ATOM   1201 C C     . HIS A 1 157 ? 206.719 191.107 219.208 1.00 53.13  ? 163 HIS J C     1 
ATOM   1202 O O     . HIS A 1 157 ? 207.142 190.010 219.575 1.00 53.13  ? 163 HIS J O     1 
ATOM   1203 C CB    . HIS A 1 157 ? 207.814 193.204 220.023 1.00 53.13  ? 163 HIS J CB    1 
ATOM   1204 C CG    . HIS A 1 157 ? 209.127 192.556 220.326 1.00 53.13  ? 163 HIS J CG    1 
ATOM   1205 N ND1   . HIS A 1 157 ? 209.475 192.131 221.589 1.00 53.13  ? 163 HIS J ND1   1 
ATOM   1206 C CD2   . HIS A 1 157 ? 210.186 192.276 219.531 1.00 53.13  ? 163 HIS J CD2   1 
ATOM   1207 C CE1   . HIS A 1 157 ? 210.689 191.612 221.559 1.00 53.13  ? 163 HIS J CE1   1 
ATOM   1208 N NE2   . HIS A 1 157 ? 211.142 191.686 220.321 1.00 53.13  ? 163 HIS J NE2   1 
ATOM   1209 N N     . ASN A 1 158 ? 206.320 191.366 217.965 1.00 53.97  ? 164 ASN J N     1 
ATOM   1210 C CA    . ASN A 1 158 ? 206.436 190.426 216.860 1.00 53.97  ? 164 ASN J CA    1 
ATOM   1211 C C     . ASN A 1 158 ? 207.340 191.031 215.799 1.00 53.97  ? 164 ASN J C     1 
ATOM   1212 O O     . ASN A 1 158 ? 207.195 192.208 215.461 1.00 53.97  ? 164 ASN J O     1 
ATOM   1213 C CB    . ASN A 1 158 ? 205.069 190.117 216.248 1.00 53.97  ? 164 ASN J CB    1 
ATOM   1214 C CG    . ASN A 1 158 ? 204.179 189.336 217.177 1.00 53.97  ? 164 ASN J CG    1 
ATOM   1215 O OD1   . ASN A 1 158 ? 204.628 188.424 217.858 1.00 53.97  ? 164 ASN J OD1   1 
ATOM   1216 N ND2   . ASN A 1 158 ? 202.904 189.686 217.204 1.00 53.97  ? 164 ASN J ND2   1 
ATOM   1217 N N     . VAL A 1 159 ? 208.267 190.236 215.278 1.00 51.00  ? 165 VAL J N     1 
ATOM   1218 C CA    . VAL A 1 159 ? 209.118 190.674 214.173 1.00 51.00  ? 165 VAL J CA    1 
ATOM   1219 C C     . VAL A 1 159 ? 209.157 189.595 213.100 1.00 51.00  ? 165 VAL J C     1 
ATOM   1220 O O     . VAL A 1 159 ? 209.843 188.578 213.271 1.00 51.00  ? 165 VAL J O     1 
ATOM   1221 C CB    . VAL A 1 159 ? 210.536 191.021 214.649 1.00 51.00  ? 165 VAL J CB    1 
ATOM   1222 C CG1   . VAL A 1 159 ? 211.337 191.591 213.505 1.00 51.00  ? 165 VAL J CG1   1 
ATOM   1223 C CG2   . VAL A 1 159 ? 210.480 192.034 215.772 1.00 51.00  ? 165 VAL J CG2   1 
ATOM   1224 N N     . PRO A 1 160 ? 208.453 189.772 211.983 1.00 49.62  ? 166 PRO J N     1 
ATOM   1225 C CA    . PRO A 1 160 ? 208.454 188.747 210.933 1.00 49.62  ? 166 PRO J CA    1 
ATOM   1226 C C     . PRO A 1 160 ? 209.708 188.850 210.076 1.00 49.62  ? 166 PRO J C     1 
ATOM   1227 O O     . PRO A 1 160 ? 210.050 189.925 209.580 1.00 49.62  ? 166 PRO J O     1 
ATOM   1228 C CB    . PRO A 1 160 ? 207.196 189.073 210.127 1.00 49.62  ? 166 PRO J CB    1 
ATOM   1229 C CG    . PRO A 1 160 ? 207.050 190.537 210.279 1.00 49.62  ? 166 PRO J CG    1 
ATOM   1230 C CD    . PRO A 1 160 ? 207.565 190.896 211.647 1.00 49.62  ? 166 PRO J CD    1 
ATOM   1231 N N     . ILE A 1 161 ? 210.394 187.724 209.906 1.00 50.19  ? 167 ILE J N     1 
ATOM   1232 C CA    . ILE A 1 161 ? 211.637 187.660 209.149 1.00 50.19  ? 167 ILE J CA    1 
ATOM   1233 C C     . ILE A 1 161 ? 211.510 186.557 208.111 1.00 50.19  ? 167 ILE J C     1 
ATOM   1234 O O     . ILE A 1 161 ? 211.040 185.459 208.425 1.00 50.19  ? 167 ILE J O     1 
ATOM   1235 C CB    . ILE A 1 161 ? 212.847 187.403 210.065 1.00 50.19  ? 167 ILE J CB    1 
ATOM   1236 C CG1   . ILE A 1 161 ? 213.013 188.551 211.055 1.00 50.19  ? 167 ILE J CG1   1 
ATOM   1237 C CG2   . ILE A 1 161 ? 214.109 187.235 209.252 1.00 50.19  ? 167 ILE J CG2   1 
ATOM   1238 C CD1   . ILE A 1 161 ? 214.208 188.408 211.950 1.00 50.19  ? 167 ILE J CD1   1 
ATOM   1239 N N     . TYR A 1 162 ? 211.927 186.845 206.881 1.00 53.86  ? 168 TYR J N     1 
ATOM   1240 C CA    . TYR A 1 162 ? 211.891 185.874 205.795 1.00 53.86  ? 168 TYR J CA    1 
ATOM   1241 C C     . TYR A 1 162 ? 213.234 185.880 205.084 1.00 53.86  ? 168 TYR J C     1 
ATOM   1242 O O     . TYR A 1 162 ? 213.647 186.913 204.550 1.00 53.86  ? 168 TYR J O     1 
ATOM   1243 C CB    . TYR A 1 162 ? 210.760 186.185 204.813 1.00 53.86  ? 168 TYR J CB    1 
ATOM   1244 C CG    . TYR A 1 162 ? 210.651 185.197 203.679 1.00 53.86  ? 168 TYR J CG    1 
ATOM   1245 C CD1   . TYR A 1 162 ? 210.008 183.984 203.851 1.00 53.86  ? 168 TYR J CD1   1 
ATOM   1246 C CD2   . TYR A 1 162 ? 211.190 185.479 202.435 1.00 53.86  ? 168 TYR J CD2   1 
ATOM   1247 C CE1   . TYR A 1 162 ? 209.908 183.079 202.819 1.00 53.86  ? 168 TYR J CE1   1 
ATOM   1248 C CE2   . TYR A 1 162 ? 211.091 184.582 201.397 1.00 53.86  ? 168 TYR J CE2   1 
ATOM   1249 C CZ    . TYR A 1 162 ? 210.452 183.384 201.595 1.00 53.86  ? 168 TYR J CZ    1 
ATOM   1250 O OH    . TYR A 1 162 ? 210.355 182.487 200.561 1.00 53.86  ? 168 TYR J OH    1 
ATOM   1251 N N     . GLU A 1 163 ? 213.909 184.729 205.085 1.00 55.28  ? 169 GLU J N     1 
ATOM   1252 C CA    . GLU A 1 163 ? 215.192 184.553 204.399 1.00 55.28  ? 169 GLU J CA    1 
ATOM   1253 C C     . GLU A 1 163 ? 216.223 185.589 204.834 1.00 55.28  ? 169 GLU J C     1 
ATOM   1254 O O     . GLU A 1 163 ? 217.112 185.957 204.065 1.00 55.28  ? 169 GLU J O     1 
ATOM   1255 C CB    . GLU A 1 163 ? 215.017 184.585 202.881 1.00 55.28  ? 169 GLU J CB    1 
ATOM   1256 C CG    . GLU A 1 163 ? 214.215 183.431 202.322 1.00 55.28  ? 169 GLU J CG    1 
ATOM   1257 C CD    . GLU A 1 163 ? 214.901 182.098 202.517 1.00 55.28  ? 169 GLU J CD    1 
ATOM   1258 O OE1   . GLU A 1 163 ? 214.192 181.086 202.697 1.00 55.28  ? 169 GLU J OE1   1 
ATOM   1259 O OE2   . GLU A 1 163 ? 216.148 182.059 202.490 1.00 55.28  ? 169 GLU J OE2   1 
ATOM   1260 N N     . GLY A 1 164 ? 216.112 186.072 206.065 1.00 51.76  ? 170 GLY J N     1 
ATOM   1261 C CA    . GLY A 1 164 ? 217.060 187.033 206.583 1.00 51.76  ? 170 GLY J CA    1 
ATOM   1262 C C     . GLY A 1 164 ? 216.737 188.482 206.308 1.00 51.76  ? 170 GLY J C     1 
ATOM   1263 O O     . GLY A 1 164 ? 217.583 189.344 206.566 1.00 51.76  ? 170 GLY J O     1 
ATOM   1264 N N     . TYR A 1 165 ? 215.549 188.781 205.794 1.00 51.57  ? 171 TYR J N     1 
ATOM   1265 C CA    . TYR A 1 165 ? 215.100 190.150 205.575 1.00 51.57  ? 171 TYR J CA    1 
ATOM   1266 C C     . TYR A 1 165 ? 213.981 190.458 206.554 1.00 51.57  ? 171 TYR J C     1 
ATOM   1267 O O     . TYR A 1 165 ? 212.971 189.749 206.586 1.00 51.57  ? 171 TYR J O     1 
ATOM   1268 C CB    . TYR A 1 165 ? 214.615 190.357 204.143 1.00 51.57  ? 171 TYR J CB    1 
ATOM   1269 C CG    . TYR A 1 165 ? 215.707 190.329 203.109 1.00 51.57  ? 171 TYR J CG    1 
ATOM   1270 C CD1   . TYR A 1 165 ? 216.475 191.451 202.857 1.00 51.57  ? 171 TYR J CD1   1 
ATOM   1271 C CD2   . TYR A 1 165 ? 215.961 189.184 202.377 1.00 51.57  ? 171 TYR J CD2   1 
ATOM   1272 C CE1   . TYR A 1 165 ? 217.469 191.430 201.914 1.00 51.57  ? 171 TYR J CE1   1 
ATOM   1273 C CE2   . TYR A 1 165 ? 216.953 189.155 201.431 1.00 51.57  ? 171 TYR J CE2   1 
ATOM   1274 C CZ    . TYR A 1 165 ? 217.704 190.279 201.204 1.00 51.57  ? 171 TYR J CZ    1 
ATOM   1275 O OH    . TYR A 1 165 ? 218.696 190.250 200.257 1.00 51.57  ? 171 TYR J OH    1 
ATOM   1276 N N     . ALA A 1 166 ? 214.156 191.509 207.343 1.00 52.01  ? 172 ALA J N     1 
ATOM   1277 C CA    . ALA A 1 166 ? 213.113 191.927 208.264 1.00 52.01  ? 172 ALA J CA    1 
ATOM   1278 C C     . ALA A 1 166 ? 212.092 192.786 207.535 1.00 52.01  ? 172 ALA J C     1 
ATOM   1279 O O     . ALA A 1 166 ? 212.443 193.588 206.667 1.00 52.01  ? 172 ALA J O     1 
ATOM   1280 C CB    . ALA A 1 166 ? 213.708 192.699 209.438 1.00 52.01  ? 172 ALA J CB    1 
ATOM   1281 N N     . LEU A 1 167 ? 210.825 192.607 207.886 1.00 53.38  ? 173 LEU J N     1 
ATOM   1282 C CA    . LEU A 1 167 ? 209.760 193.413 207.310 1.00 53.38  ? 173 LEU J CA    1 
ATOM   1283 C C     . LEU A 1 167 ? 209.334 194.451 208.338 1.00 53.38  ? 173 LEU J C     1 
ATOM   1284 O O     . LEU A 1 167 ? 208.423 194.196 209.133 1.00 53.38  ? 173 LEU J O     1 
ATOM   1285 C CB    . LEU A 1 167 ? 208.567 192.546 206.907 1.00 53.38  ? 173 LEU J CB    1 
ATOM   1286 C CG    . LEU A 1 167 ? 208.590 191.784 205.581 1.00 53.38  ? 173 LEU J CG    1 
ATOM   1287 C CD1   . LEU A 1 167 ? 208.731 192.739 204.412 1.00 53.38  ? 173 LEU J CD1   1 
ATOM   1288 C CD2   . LEU A 1 167 ? 209.670 190.718 205.552 1.00 53.38  ? 173 LEU J CD2   1 
ATOM   1289 N N     . PRO A 1 168 ? 209.958 195.630 208.353 1.00 54.43  ? 174 PRO J N     1 
ATOM   1290 C CA    . PRO A 1 168 ? 209.714 196.568 209.455 1.00 54.43  ? 174 PRO J CA    1 
ATOM   1291 C C     . PRO A 1 168 ? 208.315 197.150 209.470 1.00 54.43  ? 174 PRO J C     1 
ATOM   1292 O O     . PRO A 1 168 ? 207.853 197.571 210.536 1.00 54.43  ? 174 PRO J O     1 
ATOM   1293 C CB    . PRO A 1 168 ? 210.768 197.655 209.222 1.00 54.43  ? 174 PRO J CB    1 
ATOM   1294 C CG    . PRO A 1 168 ? 210.999 197.621 207.765 1.00 54.43  ? 174 PRO J CG    1 
ATOM   1295 C CD    . PRO A 1 168 ? 210.876 196.189 207.349 1.00 54.43  ? 174 PRO J CD    1 
ATOM   1296 N N     . HIS A 1 169 ? 207.619 197.186 208.335 1.00 56.65  ? 175 HIS J N     1 
ATOM   1297 C CA    . HIS A 1 169 ? 206.253 197.690 208.327 1.00 56.65  ? 175 HIS J CA    1 
ATOM   1298 C C     . HIS A 1 169 ? 205.274 196.735 208.991 1.00 56.65  ? 175 HIS J C     1 
ATOM   1299 O O     . HIS A 1 169 ? 204.113 197.103 209.190 1.00 56.65  ? 175 HIS J O     1 
ATOM   1300 C CB    . HIS A 1 169 ? 205.805 197.970 206.895 1.00 56.65  ? 175 HIS J CB    1 
ATOM   1301 C CG    . HIS A 1 169 ? 205.729 196.746 206.039 1.00 56.65  ? 175 HIS J CG    1 
ATOM   1302 N ND1   . HIS A 1 169 ? 204.546 196.085 205.790 1.00 56.65  ? 175 HIS J ND1   1 
ATOM   1303 C CD2   . HIS A 1 169 ? 206.689 196.062 205.374 1.00 56.65  ? 175 HIS J CD2   1 
ATOM   1304 C CE1   . HIS A 1 169 ? 204.781 195.047 205.009 1.00 56.65  ? 175 HIS J CE1   1 
ATOM   1305 N NE2   . HIS A 1 169 ? 206.074 195.009 204.743 1.00 56.65  ? 175 HIS J NE2   1 
ATOM   1306 N N     . ALA A 1 170 ? 205.706 195.525 209.333 1.00 54.88  ? 176 ALA J N     1 
ATOM   1307 C CA    . ALA A 1 170 ? 204.853 194.549 209.988 1.00 54.88  ? 176 ALA J CA    1 
ATOM   1308 C C     . ALA A 1 170 ? 205.279 194.262 211.416 1.00 54.88  ? 176 ALA J C     1 
ATOM   1309 O O     . ALA A 1 170 ? 204.733 193.347 212.038 1.00 54.88  ? 176 ALA J O     1 
ATOM   1310 C CB    . ALA A 1 170 ? 204.828 193.246 209.185 1.00 54.88  ? 176 ALA J CB    1 
ATOM   1311 N N     . ILE A 1 171 ? 206.238 195.011 211.951 1.00 54.77  ? 177 ILE J N     1 
ATOM   1312 C CA    . ILE A 1 171 ? 206.660 194.823 213.333 1.00 54.77  ? 177 ILE J CA    1 
ATOM   1313 C C     . ILE A 1 171 ? 205.605 195.429 214.247 1.00 54.77  ? 177 ILE J C     1 
ATOM   1314 O O     . ILE A 1 171 ? 205.346 196.636 214.204 1.00 54.77  ? 177 ILE J O     1 
ATOM   1315 C CB    . ILE A 1 171 ? 208.036 195.453 213.576 1.00 54.77  ? 177 ILE J CB    1 
ATOM   1316 C CG1   . ILE A 1 171 ? 209.126 194.606 212.924 1.00 54.77  ? 177 ILE J CG1   1 
ATOM   1317 C CG2   . ILE A 1 171 ? 208.299 195.598 215.061 1.00 54.77  ? 177 ILE J CG2   1 
ATOM   1318 C CD1   . ILE A 1 171 ? 210.520 195.110 213.181 1.00 54.77  ? 177 ILE J CD1   1 
ATOM   1319 N N     . MET A 1 172 ? 204.985 194.591 215.072 1.00 58.70  ? 178 MET J N     1 
ATOM   1320 C CA    . MET A 1 172 ? 203.958 195.024 216.008 1.00 58.70  ? 178 MET J CA    1 
ATOM   1321 C C     . MET A 1 172 ? 204.491 194.886 217.424 1.00 58.70  ? 178 MET J C     1 
ATOM   1322 O O     . MET A 1 172 ? 205.020 193.834 217.792 1.00 58.70  ? 178 MET J O     1 
ATOM   1323 C CB    . MET A 1 172 ? 202.675 194.208 215.837 1.00 58.70  ? 178 MET J CB    1 
ATOM   1324 C CG    . MET A 1 172 ? 201.907 194.539 214.572 1.00 58.70  ? 178 MET J CG    1 
ATOM   1325 S SD    . MET A 1 172 ? 200.535 193.415 214.261 1.00 58.70  ? 178 MET J SD    1 
ATOM   1326 C CE    . MET A 1 172 ? 199.173 194.302 215.014 1.00 58.70  ? 178 MET J CE    1 
ATOM   1327 N N     . ARG A 1 173 ? 204.355 195.948 218.210 1.00 57.91  ? 179 ARG J N     1 
ATOM   1328 C CA    . ARG A 1 173 ? 204.854 195.997 219.576 1.00 57.91  ? 179 ARG J CA    1 
ATOM   1329 C C     . ARG A 1 173 ? 203.689 196.268 220.513 1.00 57.91  ? 179 ARG J C     1 
ATOM   1330 O O     . ARG A 1 173 ? 202.858 197.140 220.243 1.00 57.91  ? 179 ARG J O     1 
ATOM   1331 C CB    . ARG A 1 173 ? 205.930 197.074 219.729 1.00 57.91  ? 179 ARG J CB    1 
ATOM   1332 C CG    . ARG A 1 173 ? 205.968 197.743 221.089 1.00 57.91  ? 179 ARG J CG    1 
ATOM   1333 C CD    . ARG A 1 173 ? 207.313 198.404 221.333 1.00 57.91  ? 179 ARG J CD    1 
ATOM   1334 N NE    . ARG A 1 173 ? 207.402 199.008 222.658 1.00 57.91  ? 179 ARG J NE    1 
ATOM   1335 C CZ    . ARG A 1 173 ? 208.528 199.462 223.195 1.00 57.91  ? 179 ARG J CZ    1 
ATOM   1336 N NH1   . ARG A 1 173 ? 209.664 199.380 222.523 1.00 57.91  ? 179 ARG J NH1   1 
ATOM   1337 N NH2   . ARG A 1 173 ? 208.519 199.998 224.405 1.00 57.91  ? 179 ARG J NH2   1 
ATOM   1338 N N     . LEU A 1 174 ? 203.632 195.519 221.606 1.00 57.71  ? 180 LEU J N     1 
ATOM   1339 C CA    . LEU A 1 174 ? 202.544 195.605 222.563 1.00 57.71  ? 180 LEU J CA    1 
ATOM   1340 C C     . LEU A 1 174 ? 203.127 195.720 223.963 1.00 57.71  ? 180 LEU J C     1 
ATOM   1341 O O     . LEU A 1 174 ? 204.145 195.101 224.278 1.00 57.71  ? 180 LEU J O     1 
ATOM   1342 C CB    . LEU A 1 174 ? 201.627 194.387 222.448 1.00 57.71  ? 180 LEU J CB    1 
ATOM   1343 C CG    . LEU A 1 174 ? 200.361 194.359 223.275 1.00 57.71  ? 180 LEU J CG    1 
ATOM   1344 C CD1   . LEU A 1 174 ? 199.665 195.702 223.233 1.00 57.71  ? 180 LEU J CD1   1 
ATOM   1345 C CD2   . LEU A 1 174 ? 199.435 193.279 222.748 1.00 57.71  ? 180 LEU J CD2   1 
ATOM   1346 N N     . ASP A 1 175 ? 202.478 196.522 224.801 1.00 61.40  ? 181 ASP J N     1 
ATOM   1347 C CA    . ASP A 1 175 ? 203.048 196.954 226.071 1.00 61.40  ? 181 ASP J CA    1 
ATOM   1348 C C     . ASP A 1 175 ? 202.433 196.256 227.282 1.00 61.40  ? 181 ASP J C     1 
ATOM   1349 O O     . ASP A 1 175 ? 202.234 196.874 228.328 1.00 61.40  ? 181 ASP J O     1 
ATOM   1350 C CB    . ASP A 1 175 ? 202.930 198.466 226.218 1.00 61.40  ? 181 ASP J CB    1 
ATOM   1351 C CG    . ASP A 1 175 ? 204.211 199.183 225.848 1.00 61.40  ? 181 ASP J CG    1 
ATOM   1352 O OD1   . ASP A 1 175 ? 205.266 198.517 225.799 1.00 61.40  ? 181 ASP J OD1   1 
ATOM   1353 O OD2   . ASP A 1 175 ? 204.169 200.410 225.613 1.00 61.40  ? 181 ASP J OD2   1 
ATOM   1354 N N     . LEU A 1 176 ? 202.129 194.965 227.172 1.00 56.74  ? 182 LEU J N     1 
ATOM   1355 C CA    . LEU A 1 176 ? 201.840 194.170 228.357 1.00 56.74  ? 182 LEU J CA    1 
ATOM   1356 C C     . LEU A 1 176 ? 202.720 192.932 228.347 1.00 56.74  ? 182 LEU J C     1 
ATOM   1357 O O     . LEU A 1 176 ? 202.861 192.261 227.322 1.00 56.74  ? 182 LEU J O     1 
ATOM   1358 C CB    . LEU A 1 176 ? 200.362 193.763 228.480 1.00 56.74  ? 182 LEU J CB    1 
ATOM   1359 C CG    . LEU A 1 176 ? 199.787 192.542 227.770 1.00 56.74  ? 182 LEU J CG    1 
ATOM   1360 C CD1   . LEU A 1 176 ? 198.501 192.128 228.432 1.00 56.74  ? 182 LEU J CD1   1 
ATOM   1361 C CD2   . LEU A 1 176 ? 199.541 192.846 226.321 1.00 56.74  ? 182 LEU J CD2   1 
ATOM   1362 N N     . ALA A 1 177 ? 203.327 192.655 229.492 1.00 55.36  ? 183 ALA J N     1 
ATOM   1363 C CA    . ALA A 1 177 ? 204.278 191.567 229.635 1.00 55.36  ? 183 ALA J CA    1 
ATOM   1364 C C     . ALA A 1 177 ? 204.178 191.055 231.066 1.00 55.36  ? 183 ALA J C     1 
ATOM   1365 O O     . ALA A 1 177 ? 203.181 191.297 231.751 1.00 55.36  ? 183 ALA J O     1 
ATOM   1366 C CB    . ALA A 1 177 ? 205.689 192.036 229.253 1.00 55.36  ? 183 ALA J CB    1 
ATOM   1367 N N     . GLY A 1 178 ? 205.210 190.343 231.514 1.00 54.59  ? 184 GLY J N     1 
ATOM   1368 C CA    . GLY A 1 178 ? 205.161 189.696 232.814 1.00 54.59  ? 184 GLY J CA    1 
ATOM   1369 C C     . GLY A 1 178 ? 204.806 190.615 233.963 1.00 54.59  ? 184 GLY J C     1 
ATOM   1370 O O     . GLY A 1 178 ? 204.136 190.197 234.907 1.00 54.59  ? 184 GLY J O     1 
ATOM   1371 N N     . ARG A 1 179 ? 205.239 191.873 233.909 1.00 57.26  ? 185 ARG J N     1 
ATOM   1372 C CA    . ARG A 1 179 ? 204.980 192.772 235.029 1.00 57.26  ? 185 ARG J CA    1 
ATOM   1373 C C     . ARG A 1 179 ? 203.499 193.112 235.142 1.00 57.26  ? 185 ARG J C     1 
ATOM   1374 O O     . ARG A 1 179 ? 202.955 193.196 236.250 1.00 57.26  ? 185 ARG J O     1 
ATOM   1375 C CB    . ARG A 1 179 ? 205.812 194.043 234.893 1.00 57.26  ? 185 ARG J CB    1 
ATOM   1376 C CG    . ARG A 1 179 ? 205.854 194.867 236.159 1.00 57.26  ? 185 ARG J CG    1 
ATOM   1377 C CD    . ARG A 1 179 ? 206.845 196.004 236.049 1.00 57.26  ? 185 ARG J CD    1 
ATOM   1378 N NE    . ARG A 1 179 ? 208.181 195.532 235.709 1.00 57.26  ? 185 ARG J NE    1 
ATOM   1379 C CZ    . ARG A 1 179 ? 209.230 196.329 235.545 1.00 57.26  ? 185 ARG J CZ    1 
ATOM   1380 N NH1   . ARG A 1 179 ? 209.098 197.638 235.696 1.00 57.26  ? 185 ARG J NH1   1 
ATOM   1381 N NH2   . ARG A 1 179 ? 210.412 195.818 235.233 1.00 57.26  ? 185 ARG J NH2   1 
ATOM   1382 N N     . ASP A 1 180 ? 202.822 193.297 234.011 1.00 57.02  ? 186 ASP J N     1 
ATOM   1383 C CA    . ASP A 1 180 ? 201.396 193.587 234.064 1.00 57.02  ? 186 ASP J CA    1 
ATOM   1384 C C     . ASP A 1 180 ? 200.596 192.372 234.510 1.00 57.02  ? 186 ASP J C     1 
ATOM   1385 O O     . ASP A 1 180 ? 199.584 192.518 235.200 1.00 57.02  ? 186 ASP J O     1 
ATOM   1386 C CB    . ASP A 1 180 ? 200.919 194.084 232.704 1.00 57.02  ? 186 ASP J CB    1 
ATOM   1387 C CG    . ASP A 1 180 ? 201.515 195.425 232.343 1.00 57.02  ? 186 ASP J CG    1 
ATOM   1388 O OD1   . ASP A 1 180 ? 201.809 196.211 233.266 1.00 57.02  ? 186 ASP J OD1   1 
ATOM   1389 O OD2   . ASP A 1 180 ? 201.700 195.696 231.142 1.00 57.02  ? 186 ASP J OD2   1 
ATOM   1390 N N     . LEU A 1 181 ? 201.044 191.168 234.154 1.00 53.25  ? 187 LEU J N     1 
ATOM   1391 C CA    . LEU A 1 181 ? 200.392 189.968 234.662 1.00 53.25  ? 187 LEU J CA    1 
ATOM   1392 C C     . LEU A 1 181 ? 200.619 189.812 236.159 1.00 53.25  ? 187 LEU J C     1 
ATOM   1393 O O     . LEU A 1 181 ? 199.721 189.375 236.885 1.00 53.25  ? 187 LEU J O     1 
ATOM   1394 C CB    . LEU A 1 181 ? 200.894 188.735 233.915 1.00 53.25  ? 187 LEU J CB    1 
ATOM   1395 C CG    . LEU A 1 181 ? 200.742 188.714 232.398 1.00 53.25  ? 187 LEU J CG    1 
ATOM   1396 C CD1   . LEU A 1 181 ? 200.866 187.297 231.892 1.00 53.25  ? 187 LEU J CD1   1 
ATOM   1397 C CD2   . LEU A 1 181 ? 199.418 189.305 231.985 1.00 53.25  ? 187 LEU J CD2   1 
ATOM   1398 N N     . THR A 1 182 ? 201.812 190.166 236.642 1.00 53.77  ? 188 THR J N     1 
ATOM   1399 C CA    . THR A 1 182 ? 202.058 190.162 238.080 1.00 53.77  ? 188 THR J CA    1 
ATOM   1400 C C     . THR A 1 182 ? 201.128 191.130 238.796 1.00 53.77  ? 188 THR J C     1 
ATOM   1401 O O     . THR A 1 182 ? 200.562 190.799 239.842 1.00 53.77  ? 188 THR J O     1 
ATOM   1402 C CB    . THR A 1 182 ? 203.513 190.522 238.370 1.00 53.77  ? 188 THR J CB    1 
ATOM   1403 O OG1   . THR A 1 182 ? 204.377 189.551 237.775 1.00 53.77  ? 188 THR J OG1   1 
ATOM   1404 C CG2   . THR A 1 182 ? 203.765 190.556 239.856 1.00 53.77  ? 188 THR J CG2   1 
ATOM   1405 N N     . ASP A 1 183 ? 200.965 192.337 238.250 1.00 56.01  ? 189 ASP J N     1 
ATOM   1406 C CA    . ASP A 1 183 ? 200.072 193.309 238.875 1.00 56.01  ? 189 ASP J CA    1 
ATOM   1407 C C     . ASP A 1 183 ? 198.625 192.836 238.846 1.00 56.01  ? 189 ASP J C     1 
ATOM   1408 O O     . ASP A 1 183 ? 197.892 193.003 239.827 1.00 56.01  ? 189 ASP J O     1 
ATOM   1409 C CB    . ASP A 1 183 ? 200.204 194.662 238.187 1.00 56.01  ? 189 ASP J CB    1 
ATOM   1410 C CG    . ASP A 1 183 ? 201.559 195.285 238.399 1.00 56.01  ? 189 ASP J CG    1 
ATOM   1411 O OD1   . ASP A 1 183 ? 202.436 194.608 238.972 1.00 56.01  ? 189 ASP J OD1   1 
ATOM   1412 O OD2   . ASP A 1 183 ? 201.748 196.452 237.998 1.00 56.01  ? 189 ASP J OD2   1 
ATOM   1413 N N     . TYR A 1 184 ? 198.190 192.246 237.734 1.00 52.63  ? 190 TYR J N     1 
ATOM   1414 C CA    . TYR A 1 184 ? 196.831 191.728 237.680 1.00 52.63  ? 190 TYR J CA    1 
ATOM   1415 C C     . TYR A 1 184 ? 196.629 190.576 238.652 1.00 52.63  ? 190 TYR J C     1 
ATOM   1416 O O     . TYR A 1 184 ? 195.552 190.449 239.230 1.00 52.63  ? 190 TYR J O     1 
ATOM   1417 C CB    . TYR A 1 184 ? 196.478 191.282 236.266 1.00 52.63  ? 190 TYR J CB    1 
ATOM   1418 C CG    . TYR A 1 184 ? 195.044 190.835 236.126 1.00 52.63  ? 190 TYR J CG    1 
ATOM   1419 C CD1   . TYR A 1 184 ? 194.000 191.699 236.412 1.00 52.63  ? 190 TYR J CD1   1 
ATOM   1420 C CD2   . TYR A 1 184 ? 194.734 189.551 235.716 1.00 52.63  ? 190 TYR J CD2   1 
ATOM   1421 C CE1   . TYR A 1 184 ? 192.691 191.299 236.288 1.00 52.63  ? 190 TYR J CE1   1 
ATOM   1422 C CE2   . TYR A 1 184 ? 193.427 189.144 235.589 1.00 52.63  ? 190 TYR J CE2   1 
ATOM   1423 C CZ    . TYR A 1 184 ? 192.411 190.023 235.875 1.00 52.63  ? 190 TYR J CZ    1 
ATOM   1424 O OH    . TYR A 1 184 ? 191.104 189.620 235.750 1.00 52.63  ? 190 TYR J OH    1 
ATOM   1425 N N     . LEU A 1 185 ? 197.643 189.736 238.859 1.00 52.92  ? 191 LEU J N     1 
ATOM   1426 C CA    . LEU A 1 185 ? 197.514 188.671 239.849 1.00 52.92  ? 191 LEU J CA    1 
ATOM   1427 C C     . LEU A 1 185 ? 197.456 189.240 241.259 1.00 52.92  ? 191 LEU J C     1 
ATOM   1428 O O     . LEU A 1 185 ? 196.676 188.771 242.096 1.00 52.92  ? 191 LEU J O     1 
ATOM   1429 C CB    . LEU A 1 185 ? 198.670 187.684 239.718 1.00 52.92  ? 191 LEU J CB    1 
ATOM   1430 C CG    . LEU A 1 185 ? 198.667 186.520 240.704 1.00 52.92  ? 191 LEU J CG    1 
ATOM   1431 C CD1   . LEU A 1 185 ? 197.412 185.693 240.540 1.00 52.92  ? 191 LEU J CD1   1 
ATOM   1432 C CD2   . LEU A 1 185 ? 199.896 185.665 240.513 1.00 52.92  ? 191 LEU J CD2   1 
ATOM   1433 N N     . MET A 1 186 ? 198.280 190.248 241.539 1.00 57.86  ? 192 MET J N     1 
ATOM   1434 C CA    . MET A 1 186 ? 198.241 190.910 242.836 1.00 57.86  ? 192 MET J CA    1 
ATOM   1435 C C     . MET A 1 186 ? 196.873 191.526 243.097 1.00 57.86  ? 192 MET J C     1 
ATOM   1436 O O     . MET A 1 186 ? 196.380 191.509 244.230 1.00 57.86  ? 192 MET J O     1 
ATOM   1437 C CB    . MET A 1 186 ? 199.340 191.968 242.896 1.00 57.86  ? 192 MET J CB    1 
ATOM   1438 C CG    . MET A 1 186 ? 199.476 192.686 244.212 1.00 57.86  ? 192 MET J CG    1 
ATOM   1439 S SD    . MET A 1 186 ? 200.836 193.867 244.156 1.00 57.86  ? 192 MET J SD    1 
ATOM   1440 C CE    . MET A 1 186 ? 200.154 195.119 243.074 1.00 57.86  ? 192 MET J CE    1 
ATOM   1441 N N     . LYS A 1 187 ? 196.242 192.072 242.057 1.00 53.54  ? 193 LYS J N     1 
ATOM   1442 C CA    . LYS A 1 187 ? 194.926 192.681 242.227 1.00 53.54  ? 193 LYS J CA    1 
ATOM   1443 C C     . LYS A 1 187 ? 193.817 191.636 242.277 1.00 53.54  ? 193 LYS J C     1 
ATOM   1444 O O     . LYS A 1 187 ? 192.790 191.854 242.925 1.00 53.54  ? 193 LYS J O     1 
ATOM   1445 C CB    . LYS A 1 187 ? 194.674 193.682 241.101 1.00 53.54  ? 193 LYS J CB    1 
ATOM   1446 C CG    . LYS A 1 187 ? 193.318 194.357 241.132 1.00 53.54  ? 193 LYS J CG    1 
ATOM   1447 C CD    . LYS A 1 187 ? 192.419 193.838 240.026 1.00 53.54  ? 193 LYS J CD    1 
ATOM   1448 C CE    . LYS A 1 187 ? 191.094 194.576 239.999 1.00 53.54  ? 193 LYS J CE    1 
ATOM   1449 N NZ    . LYS A 1 187 ? 190.236 194.123 238.873 1.00 53.54  ? 193 LYS J NZ    1 
ATOM   1450 N N     . ILE A 1 188 ? 194.007 190.498 241.616 1.00 53.48  ? 194 ILE J N     1 
ATOM   1451 C CA    . ILE A 1 188 ? 192.984 189.463 241.578 1.00 53.48  ? 194 ILE J CA    1 
ATOM   1452 C C     . ILE A 1 188 ? 193.043 188.563 242.803 1.00 53.48  ? 194 ILE J C     1 
ATOM   1453 O O     . ILE A 1 188 ? 192.085 187.825 243.067 1.00 53.48  ? 194 ILE J O     1 
ATOM   1454 C CB    . ILE A 1 188 ? 193.136 188.624 240.297 1.00 53.48  ? 194 ILE J CB    1 
ATOM   1455 C CG1   . ILE A 1 188 ? 191.866 187.866 239.968 1.00 53.48  ? 194 ILE J CG1   1 
ATOM   1456 C CG2   . ILE A 1 188 ? 194.215 187.592 240.455 1.00 53.48  ? 194 ILE J CG2   1 
ATOM   1457 C CD1   . ILE A 1 188 ? 191.951 187.225 238.622 1.00 53.48  ? 194 ILE J CD1   1 
ATOM   1458 N N     . LEU A 1 189 ? 194.142 188.595 243.555 1.00 54.01  ? 195 LEU J N     1 
ATOM   1459 C CA    . LEU A 1 189 ? 194.235 187.794 244.765 1.00 54.01  ? 195 LEU J CA    1 
ATOM   1460 C C     . LEU A 1 189 ? 193.467 188.397 245.931 1.00 54.01  ? 195 LEU J C     1 
ATOM   1461 O O     . LEU A 1 189 ? 193.029 187.652 246.811 1.00 54.01  ? 195 LEU J O     1 
ATOM   1462 C CB    . LEU A 1 189 ? 195.700 187.607 245.162 1.00 54.01  ? 195 LEU J CB    1 
ATOM   1463 C CG    . LEU A 1 189 ? 196.416 186.410 244.544 1.00 54.01  ? 195 LEU J CG    1 
ATOM   1464 C CD1   . LEU A 1 189 ? 197.851 186.361 245.004 1.00 54.01  ? 195 LEU J CD1   1 
ATOM   1465 C CD2   . LEU A 1 189 ? 195.701 185.136 244.907 1.00 54.01  ? 195 LEU J CD2   1 
ATOM   1466 N N     . THR A 1 190 ? 193.295 189.720 245.960 1.00 56.33  ? 196 THR J N     1 
ATOM   1467 C CA    . THR A 1 190 ? 192.596 190.354 247.072 1.00 56.33  ? 196 THR J CA    1 
ATOM   1468 C C     . THR A 1 190 ? 191.156 189.884 247.198 1.00 56.33  ? 196 THR J C     1 
ATOM   1469 O O     . THR A 1 190 ? 190.598 189.932 248.298 1.00 56.33  ? 196 THR J O     1 
ATOM   1470 C CB    . THR A 1 190 ? 192.623 191.874 246.932 1.00 56.33  ? 196 THR J CB    1 
ATOM   1471 O OG1   . THR A 1 190 ? 191.632 192.286 245.987 1.00 56.33  ? 196 THR J OG1   1 
ATOM   1472 C CG2   . THR A 1 190 ? 193.988 192.339 246.468 1.00 56.33  ? 196 THR J CG2   1 
ATOM   1473 N N     . GLU A 1 191 ? 190.545 189.421 246.113 1.00 58.59  ? 197 GLU J N     1 
ATOM   1474 C CA    . GLU A 1 191 ? 189.191 188.892 246.178 1.00 58.59  ? 197 GLU J CA    1 
ATOM   1475 C C     . GLU A 1 191 ? 189.124 187.531 246.857 1.00 58.59  ? 197 GLU J C     1 
ATOM   1476 O O     . GLU A 1 191 ? 188.052 186.921 246.891 1.00 58.59  ? 197 GLU J O     1 
ATOM   1477 C CB    . GLU A 1 191 ? 188.588 188.811 244.775 1.00 58.59  ? 197 GLU J CB    1 
ATOM   1478 C CG    . GLU A 1 191 ? 189.026 187.612 243.962 1.00 58.59  ? 197 GLU J CG    1 
ATOM   1479 C CD    . GLU A 1 191 ? 188.557 187.694 242.526 1.00 58.59  ? 197 GLU J CD    1 
ATOM   1480 O OE1   . GLU A 1 191 ? 188.381 188.824 242.025 1.00 58.59  ? 197 GLU J OE1   1 
ATOM   1481 O OE2   . GLU A 1 191 ? 188.364 186.633 241.899 1.00 58.59  ? 197 GLU J OE2   1 
ATOM   1482 N N     . ARG A 1 192 ? 190.238 187.046 247.398 1.00 59.41  ? 198 ARG J N     1 
ATOM   1483 C CA    . ARG A 1 192 ? 190.255 185.830 248.190 1.00 59.41  ? 198 ARG J CA    1 
ATOM   1484 C C     . ARG A 1 192 ? 190.713 186.048 249.622 1.00 59.41  ? 198 ARG J C     1 
ATOM   1485 O O     . ARG A 1 192 ? 190.685 185.096 250.408 1.00 59.41  ? 198 ARG J O     1 
ATOM   1486 C CB    . ARG A 1 192 ? 191.160 184.775 247.539 1.00 59.41  ? 198 ARG J CB    1 
ATOM   1487 C CG    . ARG A 1 192 ? 190.420 183.598 246.942 1.00 59.41  ? 198 ARG J CG    1 
ATOM   1488 C CD    . ARG A 1 192 ? 191.395 182.600 246.351 1.00 59.41  ? 198 ARG J CD    1 
ATOM   1489 N NE    . ARG A 1 192 ? 190.721 181.459 245.742 1.00 59.41  ? 198 ARG J NE    1 
ATOM   1490 C CZ    . ARG A 1 192 ? 190.431 180.336 246.386 1.00 59.41  ? 198 ARG J CZ    1 
ATOM   1491 N NH1   . ARG A 1 192 ? 190.754 180.203 247.663 1.00 59.41  ? 198 ARG J NH1   1 
ATOM   1492 N NH2   . ARG A 1 192 ? 189.820 179.345 245.754 1.00 59.41  ? 198 ARG J NH2   1 
ATOM   1493 N N     . GLY A 1 193 ? 191.137 187.254 249.982 1.00 59.37  ? 199 GLY J N     1 
ATOM   1494 C CA    . GLY A 1 193 ? 191.550 187.565 251.337 1.00 59.37  ? 199 GLY J CA    1 
ATOM   1495 C C     . GLY A 1 193 ? 193.013 187.914 251.499 1.00 59.37  ? 199 GLY J C     1 
ATOM   1496 O O     . GLY A 1 193 ? 193.398 188.401 252.572 1.00 59.37  ? 199 GLY J O     1 
ATOM   1497 N N     . TYR A 1 194 ? 193.851 187.693 250.490 1.00 58.12  ? 200 TYR J N     1 
ATOM   1498 C CA    . TYR A 1 194 ? 195.276 187.980 250.583 1.00 58.12  ? 200 TYR J CA    1 
ATOM   1499 C C     . TYR A 1 194 ? 195.569 189.353 249.998 1.00 58.12  ? 200 TYR J C     1 
ATOM   1500 O O     . TYR A 1 194 ? 195.109 189.675 248.899 1.00 58.12  ? 200 TYR J O     1 
ATOM   1501 C CB    . TYR A 1 194 ? 196.083 186.911 249.850 1.00 58.12  ? 200 TYR J CB    1 
ATOM   1502 C CG    . TYR A 1 194 ? 195.497 185.530 249.979 1.00 58.12  ? 200 TYR J CG    1 
ATOM   1503 C CD1   . TYR A 1 194 ? 195.539 184.852 251.184 1.00 58.12  ? 200 TYR J CD1   1 
ATOM   1504 C CD2   . TYR A 1 194 ? 194.897 184.906 248.898 1.00 58.12  ? 200 TYR J CD2   1 
ATOM   1505 C CE1   . TYR A 1 194 ? 195.002 183.590 251.310 1.00 58.12  ? 200 TYR J CE1   1 
ATOM   1506 C CE2   . TYR A 1 194 ? 194.358 183.643 249.015 1.00 58.12  ? 200 TYR J CE2   1 
ATOM   1507 C CZ    . TYR A 1 194 ? 194.414 182.991 250.224 1.00 58.12  ? 200 TYR J CZ    1 
ATOM   1508 O OH    . TYR A 1 194 ? 193.879 181.734 250.351 1.00 58.12  ? 200 TYR J OH    1 
ATOM   1509 N N     . SER A 1 195 ? 196.343 190.155 250.723 1.00 58.66  ? 201 SER J N     1 
ATOM   1510 C CA    . SER A 1 195 ? 196.646 191.526 250.326 1.00 58.66  ? 201 SER J CA    1 
ATOM   1511 C C     . SER A 1 195 ? 198.155 191.700 250.235 1.00 58.66  ? 201 SER J C     1 
ATOM   1512 O O     . SER A 1 195 ? 198.865 191.544 251.234 1.00 58.66  ? 201 SER J O     1 
ATOM   1513 C CB    . SER A 1 195 ? 196.044 192.525 251.310 1.00 58.66  ? 201 SER J CB    1 
ATOM   1514 O OG    . SER A 1 195 ? 195.978 193.820 250.741 1.00 58.66  ? 201 SER J OG    1 
ATOM   1515 N N     . PHE A 1 196 ? 198.640 192.025 249.039 1.00 57.85  ? 202 PHE J N     1 
ATOM   1516 C CA    . PHE A 1 196 ? 200.049 192.306 248.795 1.00 57.85  ? 202 PHE J CA    1 
ATOM   1517 C C     . PHE A 1 196 ? 200.170 193.723 248.254 1.00 57.85  ? 202 PHE J C     1 
ATOM   1518 O O     . PHE A 1 196 ? 199.602 194.037 247.204 1.00 57.85  ? 202 PHE J O     1 
ATOM   1519 C CB    . PHE A 1 196 ? 200.646 191.302 247.809 1.00 57.85  ? 202 PHE J CB    1 
ATOM   1520 C CG    . PHE A 1 196 ? 200.498 189.872 248.234 1.00 57.85  ? 202 PHE J CG    1 
ATOM   1521 C CD1   . PHE A 1 196 ? 201.240 189.367 249.283 1.00 57.85  ? 202 PHE J CD1   1 
ATOM   1522 C CD2   . PHE A 1 196 ? 199.621 189.030 247.582 1.00 57.85  ? 202 PHE J CD2   1 
ATOM   1523 C CE1   . PHE A 1 196 ? 201.107 188.051 249.669 1.00 57.85  ? 202 PHE J CE1   1 
ATOM   1524 C CE2   . PHE A 1 196 ? 199.487 187.715 247.965 1.00 57.85  ? 202 PHE J CE2   1 
ATOM   1525 C CZ    . PHE A 1 196 ? 200.229 187.227 249.008 1.00 57.85  ? 202 PHE J CZ    1 
ATOM   1526 N N     . VAL A 1 197 ? 200.901 194.576 248.967 1.00 63.69  ? 203 VAL J N     1 
ATOM   1527 C CA    . VAL A 1 197 ? 201.009 195.977 248.575 1.00 63.69  ? 203 VAL J CA    1 
ATOM   1528 C C     . VAL A 1 197 ? 202.464 196.392 248.408 1.00 63.69  ? 203 VAL J C     1 
ATOM   1529 O O     . VAL A 1 197 ? 202.772 197.322 247.655 1.00 63.69  ? 203 VAL J O     1 
ATOM   1530 C CB    . VAL A 1 197 ? 200.302 196.881 249.600 1.00 63.69  ? 203 VAL J CB    1 
ATOM   1531 C CG1   . VAL A 1 197 ? 198.800 196.702 249.511 1.00 63.69  ? 203 VAL J CG1   1 
ATOM   1532 C CG2   . VAL A 1 197 ? 200.792 196.568 251.002 1.00 63.69  ? 203 VAL J CG2   1 
ATOM   1533 N N     . THR A 1 198 ? 203.367 195.709 249.099 1.00 63.06  ? 204 THR J N     1 
ATOM   1534 C CA    . THR A 1 198 ? 204.767 196.092 249.071 1.00 63.06  ? 204 THR J CA    1 
ATOM   1535 C C     . THR A 1 198 ? 205.459 195.450 247.868 1.00 63.06  ? 204 THR J C     1 
ATOM   1536 O O     . THR A 1 198 ? 205.002 194.441 247.325 1.00 63.06  ? 204 THR J O     1 
ATOM   1537 C CB    . THR A 1 198 ? 205.442 195.683 250.384 1.00 63.06  ? 204 THR J CB    1 
ATOM   1538 O OG1   . THR A 1 198 ? 204.660 196.163 251.482 1.00 63.06  ? 204 THR J OG1   1 
ATOM   1539 C CG2   . THR A 1 198 ? 206.827 196.294 250.504 1.00 63.06  ? 204 THR J CG2   1 
ATOM   1540 N N     . THR A 1 199 ? 206.573 196.055 247.446 1.00 62.18  ? 205 THR J N     1 
ATOM   1541 C CA    . THR A 1 199 ? 207.327 195.520 246.316 1.00 62.18  ? 205 THR J CA    1 
ATOM   1542 C C     . THR A 1 199 ? 207.935 194.158 246.633 1.00 62.18  ? 205 THR J C     1 
ATOM   1543 O O     . THR A 1 199 ? 208.028 193.300 245.747 1.00 62.18  ? 205 THR J O     1 
ATOM   1544 C CB    . THR A 1 199 ? 208.412 196.507 245.901 1.00 62.18  ? 205 THR J CB    1 
ATOM   1545 O OG1   . THR A 1 199 ? 209.295 196.728 247.003 1.00 62.18  ? 205 THR J OG1   1 
ATOM   1546 C CG2   . THR A 1 199 ? 207.797 197.828 245.496 1.00 62.18  ? 205 THR J CG2   1 
ATOM   1547 N N     . ALA A 1 200 ? 208.357 193.940 247.879 1.00 62.73  ? 206 ALA J N     1 
ATOM   1548 C CA    . ALA A 1 200 ? 208.735 192.597 248.305 1.00 62.73  ? 206 ALA J CA    1 
ATOM   1549 C C     . ALA A 1 200 ? 207.586 191.621 248.087 1.00 62.73  ? 206 ALA J C     1 
ATOM   1550 O O     . ALA A 1 200 ? 207.772 190.512 247.563 1.00 62.73  ? 206 ALA J O     1 
ATOM   1551 C CB    . ALA A 1 200 ? 209.151 192.618 249.775 1.00 62.73  ? 206 ALA J CB    1 
ATOM   1552 N N     . GLU A 1 201 ? 206.381 192.025 248.479 1.00 64.37  ? 207 GLU J N     1 
ATOM   1553 C CA    . GLU A 1 201 ? 205.217 191.188 248.246 1.00 64.37  ? 207 GLU J CA    1 
ATOM   1554 C C     . GLU A 1 201 ? 204.913 191.066 246.759 1.00 64.37  ? 207 GLU J C     1 
ATOM   1555 O O     . GLU A 1 201 ? 204.359 190.052 246.326 1.00 64.37  ? 207 GLU J O     1 
ATOM   1556 C CB    . GLU A 1 201 ? 204.036 191.749 249.031 1.00 64.37  ? 207 GLU J CB    1 
ATOM   1557 C CG    . GLU A 1 201 ? 204.240 191.615 250.537 1.00 64.37  ? 207 GLU J CG    1 
ATOM   1558 C CD    . GLU A 1 201 ? 203.189 192.333 251.362 1.00 64.37  ? 207 GLU J CD    1 
ATOM   1559 O OE1   . GLU A 1 201 ? 202.385 193.090 250.783 1.00 64.37  ? 207 GLU J OE1   1 
ATOM   1560 O OE2   . GLU A 1 201 ? 203.170 192.147 252.597 1.00 64.37  ? 207 GLU J OE2   1 
ATOM   1561 N N     . ARG A 1 202 ? 205.306 192.057 245.956 1.00 63.73  ? 208 ARG J N     1 
ATOM   1562 C CA    . ARG A 1 202 ? 205.199 191.904 244.509 1.00 63.73  ? 208 ARG J CA    1 
ATOM   1563 C C     . ARG A 1 202 ? 206.120 190.801 244.004 1.00 63.73  ? 208 ARG J C     1 
ATOM   1564 O O     . ARG A 1 202 ? 205.750 190.038 243.107 1.00 63.73  ? 208 ARG J O     1 
ATOM   1565 C CB    . ARG A 1 202 ? 205.514 193.223 243.808 1.00 63.73  ? 208 ARG J CB    1 
ATOM   1566 C CG    . ARG A 1 202 ? 205.089 193.252 242.353 1.00 63.73  ? 208 ARG J CG    1 
ATOM   1567 C CD    . ARG A 1 202 ? 204.530 194.606 241.960 1.00 63.73  ? 208 ARG J CD    1 
ATOM   1568 N NE    . ARG A 1 202 ? 205.509 195.669 242.147 1.00 63.73  ? 208 ARG J NE    1 
ATOM   1569 C CZ    . ARG A 1 202 ? 206.368 196.059 241.212 1.00 63.73  ? 208 ARG J CZ    1 
ATOM   1570 N NH1   . ARG A 1 202 ? 206.366 195.471 240.024 1.00 63.73  ? 208 ARG J NH1   1 
ATOM   1571 N NH2   . ARG A 1 202 ? 207.231 197.035 241.464 1.00 63.73  ? 208 ARG J NH2   1 
ATOM   1572 N N     . GLU A 1 203 ? 207.322 190.692 244.572 1.00 61.88  ? 209 GLU J N     1 
ATOM   1573 C CA    . GLU A 1 203 ? 208.206 189.594 244.192 1.00 61.88  ? 209 GLU J CA    1 
ATOM   1574 C C     . GLU A 1 203 ? 207.633 188.252 244.629 1.00 61.88  ? 209 GLU J C     1 
ATOM   1575 O O     . GLU A 1 203 ? 207.752 187.247 243.912 1.00 61.88  ? 209 GLU J O     1 
ATOM   1576 C CB    . GLU A 1 203 ? 209.590 189.807 244.794 1.00 61.88  ? 209 GLU J CB    1 
ATOM   1577 C CG    . GLU A 1 203 ? 210.234 191.111 244.379 1.00 61.88  ? 209 GLU J CG    1 
ATOM   1578 C CD    . GLU A 1 203 ? 210.367 191.244 242.875 1.00 61.88  ? 209 GLU J CD    1 
ATOM   1579 O OE1   . GLU A 1 203 ? 210.857 190.292 242.233 1.00 61.88  ? 209 GLU J OE1   1 
ATOM   1580 O OE2   . GLU A 1 203 ? 209.980 192.302 242.335 1.00 61.88  ? 209 GLU J OE2   1 
ATOM   1581 N N     . ILE A 1 204 ? 207.007 188.216 245.805 1.00 60.75  ? 210 ILE J N     1 
ATOM   1582 C CA    . ILE A 1 204 ? 206.338 186.991 246.241 1.00 60.75  ? 210 ILE J CA    1 
ATOM   1583 C C     . ILE A 1 204 ? 205.242 186.604 245.253 1.00 60.75  ? 210 ILE J C     1 
ATOM   1584 O O     . ILE A 1 204 ? 205.103 185.431 244.880 1.00 60.75  ? 210 ILE J O     1 
ATOM   1585 C CB    . ILE A 1 204 ? 205.784 187.160 247.666 1.00 60.75  ? 210 ILE J CB    1 
ATOM   1586 C CG1   . ILE A 1 204 ? 206.927 187.316 248.666 1.00 60.75  ? 210 ILE J CG1   1 
ATOM   1587 C CG2   . ILE A 1 204 ? 204.926 185.973 248.048 1.00 60.75  ? 210 ILE J CG2   1 
ATOM   1588 C CD1   . ILE A 1 204 ? 206.461 187.542 250.078 1.00 60.75  ? 210 ILE J CD1   1 
ATOM   1589 N N     . VAL A 1 205 ? 204.452 187.584 244.812 1.00 57.74  ? 211 VAL J N     1 
ATOM   1590 C CA    . VAL A 1 205 ? 203.405 187.315 243.829 1.00 57.74  ? 211 VAL J CA    1 
ATOM   1591 C C     . VAL A 1 205 ? 204.014 186.820 242.525 1.00 57.74  ? 211 VAL J C     1 
ATOM   1592 O O     . VAL A 1 205 ? 203.455 185.946 241.854 1.00 57.74  ? 211 VAL J O     1 
ATOM   1593 C CB    . VAL A 1 205 ? 202.543 188.570 243.606 1.00 57.74  ? 211 VAL J CB    1 
ATOM   1594 C CG1   . VAL A 1 205 ? 201.564 188.341 242.482 1.00 57.74  ? 211 VAL J CG1   1 
ATOM   1595 C CG2   . VAL A 1 205 ? 201.797 188.922 244.864 1.00 57.74  ? 211 VAL J CG2   1 
ATOM   1596 N N     . ARG A 1 206 ? 205.162 187.376 242.140 1.00 56.92  ? 212 ARG J N     1 
ATOM   1597 C CA    . ARG A 1 206 ? 205.836 186.902 240.939 1.00 56.92  ? 212 ARG J CA    1 
ATOM   1598 C C     . ARG A 1 206 ? 206.198 185.430 241.060 1.00 56.92  ? 212 ARG J C     1 
ATOM   1599 O O     . ARG A 1 206 ? 206.033 184.661 240.107 1.00 56.92  ? 212 ARG J O     1 
ATOM   1600 C CB    . ARG A 1 206 ? 207.087 187.732 240.670 1.00 56.92  ? 212 ARG J CB    1 
ATOM   1601 C CG    . ARG A 1 206 ? 207.768 187.386 239.368 1.00 56.92  ? 212 ARG J CG    1 
ATOM   1602 C CD    . ARG A 1 206 ? 208.947 188.291 239.102 1.00 56.92  ? 212 ARG J CD    1 
ATOM   1603 N NE    . ARG A 1 206 ? 209.835 188.370 240.254 1.00 56.92  ? 212 ARG J NE    1 
ATOM   1604 C CZ    . ARG A 1 206 ? 210.707 187.426 240.589 1.00 56.92  ? 212 ARG J CZ    1 
ATOM   1605 N NH1   . ARG A 1 206 ? 210.812 186.326 239.858 1.00 56.92  ? 212 ARG J NH1   1 
ATOM   1606 N NH2   . ARG A 1 206 ? 211.476 187.582 241.658 1.00 56.92  ? 212 ARG J NH2   1 
ATOM   1607 N N     . ASP A 1 207 ? 206.685 185.015 242.228 1.00 58.04  ? 213 ASP J N     1 
ATOM   1608 C CA    . ASP A 1 207 ? 207.030 183.604 242.388 1.00 58.04  ? 213 ASP J CA    1 
ATOM   1609 C C     . ASP A 1 207 ? 205.787 182.721 242.373 1.00 58.04  ? 213 ASP J C     1 
ATOM   1610 O O     . ASP A 1 207 ? 205.811 181.614 241.820 1.00 58.04  ? 213 ASP J O     1 
ATOM   1611 C CB    . ASP A 1 207 ? 207.825 183.380 243.669 1.00 58.04  ? 213 ASP J CB    1 
ATOM   1612 C CG    . ASP A 1 207 ? 208.393 181.974 243.753 1.00 58.04  ? 213 ASP J CG    1 
ATOM   1613 O OD1   . ASP A 1 207 ? 208.075 181.250 244.720 1.00 58.04  ? 213 ASP J OD1   1 
ATOM   1614 O OD2   . ASP A 1 207 ? 209.149 181.586 242.841 1.00 58.04  ? 213 ASP J OD2   1 
ATOM   1615 N N     . ILE A 1 208 ? 204.693 183.188 242.976 1.00 56.14  ? 214 ILE J N     1 
ATOM   1616 C CA    . ILE A 1 208 ? 203.440 182.436 242.894 1.00 56.14  ? 214 ILE J CA    1 
ATOM   1617 C C     . ILE A 1 208 ? 203.025 182.262 241.440 1.00 56.14  ? 214 ILE J C     1 
ATOM   1618 O O     . ILE A 1 208 ? 202.615 181.174 241.017 1.00 56.14  ? 214 ILE J O     1 
ATOM   1619 C CB    . ILE A 1 208 ? 202.333 183.128 243.708 1.00 56.14  ? 214 ILE J CB    1 
ATOM   1620 C CG1   . ILE A 1 208 ? 202.772 183.340 245.152 1.00 56.14  ? 214 ILE J CG1   1 
ATOM   1621 C CG2   . ILE A 1 208 ? 201.061 182.311 243.661 1.00 56.14  ? 214 ILE J CG2   1 
ATOM   1622 C CD1   . ILE A 1 208 ? 201.781 184.120 245.973 1.00 56.14  ? 214 ILE J CD1   1 
ATOM   1623 N N     . LYS A 1 209 ? 203.127 183.337 240.656 1.00 53.60  ? 215 LYS J N     1 
ATOM   1624 C CA    . LYS A 1 209 ? 202.776 183.285 239.243 1.00 53.60  ? 215 LYS J CA    1 
ATOM   1625 C C     . LYS A 1 209 ? 203.649 182.303 238.482 1.00 53.60  ? 215 LYS J C     1 
ATOM   1626 O O     . LYS A 1 209 ? 203.146 181.544 237.649 1.00 53.60  ? 215 LYS J O     1 
ATOM   1627 C CB    . LYS A 1 209 ? 202.905 184.677 238.631 1.00 53.60  ? 215 LYS J CB    1 
ATOM   1628 C CG    . LYS A 1 209 ? 202.591 184.745 237.159 1.00 53.60  ? 215 LYS J CG    1 
ATOM   1629 C CD    . LYS A 1 209 ? 202.651 186.174 236.668 1.00 53.60  ? 215 LYS J CD    1 
ATOM   1630 C CE    . LYS A 1 209 ? 204.078 186.674 236.601 1.00 53.60  ? 215 LYS J CE    1 
ATOM   1631 N NZ    . LYS A 1 209 ? 204.841 186.013 235.523 1.00 53.60  ? 215 LYS J NZ    1 
ATOM   1632 N N     . GLU A 1 210 ? 204.948 182.295 238.757 1.00 55.37  ? 216 GLU J N     1 
ATOM   1633 C CA    . GLU A 1 210 ? 205.846 181.380 238.071 1.00 55.37  ? 216 GLU J CA    1 
ATOM   1634 C C     . GLU A 1 210 ? 205.649 179.932 238.484 1.00 55.37  ? 216 GLU J C     1 
ATOM   1635 O O     . GLU A 1 210 ? 205.965 179.033 237.700 1.00 55.37  ? 216 GLU J O     1 
ATOM   1636 C CB    . GLU A 1 210 ? 207.302 181.772 238.321 1.00 55.37  ? 216 GLU J CB    1 
ATOM   1637 C CG    . GLU A 1 210 ? 207.654 183.177 237.888 1.00 55.37  ? 216 GLU J CG    1 
ATOM   1638 C CD    . GLU A 1 210 ? 209.026 183.601 238.367 1.00 55.37  ? 216 GLU J CD    1 
ATOM   1639 O OE1   . GLU A 1 210 ? 209.744 182.754 238.936 1.00 55.37  ? 216 GLU J OE1   1 
ATOM   1640 O OE2   . GLU A 1 210 ? 209.386 184.779 238.179 1.00 55.37  ? 216 GLU J OE2   1 
ATOM   1641 N N     . LYS A 1 211 ? 205.132 179.678 239.684 1.00 57.88  ? 217 LYS J N     1 
ATOM   1642 C CA    . LYS A 1 211 ? 205.007 178.302 240.148 1.00 57.88  ? 217 LYS J CA    1 
ATOM   1643 C C     . LYS A 1 211 ? 203.642 177.676 239.900 1.00 57.88  ? 217 LYS J C     1 
ATOM   1644 O O     . LYS A 1 211 ? 203.571 176.462 239.694 1.00 57.88  ? 217 LYS J O     1 
ATOM   1645 C CB    . LYS A 1 211 ? 205.321 178.213 241.643 1.00 57.88  ? 217 LYS J CB    1 
ATOM   1646 C CG    . LYS A 1 211 ? 206.744 178.578 241.991 1.00 57.88  ? 217 LYS J CG    1 
ATOM   1647 C CD    . LYS A 1 211 ? 207.287 177.679 243.082 1.00 57.88  ? 217 LYS J CD    1 
ATOM   1648 C CE    . LYS A 1 211 ? 208.668 178.132 243.510 1.00 57.88  ? 217 LYS J CE    1 
ATOM   1649 N NZ    . LYS A 1 211 ? 209.473 178.589 242.343 1.00 57.88  ? 217 LYS J NZ    1 
ATOM   1650 N N     . LEU A 1 212 ? 202.554 178.449 239.911 1.00 57.82  ? 218 LEU J N     1 
ATOM   1651 C CA    . LEU A 1 212 ? 201.226 177.850 239.901 1.00 57.82  ? 218 LEU J CA    1 
ATOM   1652 C C     . LEU A 1 212 ? 200.349 178.220 238.713 1.00 57.82  ? 218 LEU J C     1 
ATOM   1653 O O     . LEU A 1 212 ? 199.353 177.528 238.476 1.00 57.82  ? 218 LEU J O     1 
ATOM   1654 C CB    . LEU A 1 212 ? 200.474 178.205 241.192 1.00 57.82  ? 218 LEU J CB    1 
ATOM   1655 C CG    . LEU A 1 212 ? 201.062 177.651 242.489 1.00 57.82  ? 218 LEU J CG    1 
ATOM   1656 C CD1   . LEU A 1 212 ? 200.069 177.778 243.619 1.00 57.82  ? 218 LEU J CD1   1 
ATOM   1657 C CD2   . LEU A 1 212 ? 201.476 176.209 242.313 1.00 57.82  ? 218 LEU J CD2   1 
ATOM   1658 N N     . CYS A 1 213 ? 200.671 179.266 237.962 1.00 55.30  ? 219 CYS J N     1 
ATOM   1659 C CA    . CYS A 1 213 ? 199.796 179.731 236.897 1.00 55.30  ? 219 CYS J CA    1 
ATOM   1660 C C     . CYS A 1 213 ? 200.005 178.927 235.621 1.00 55.30  ? 219 CYS J C     1 
ATOM   1661 O O     . CYS A 1 213 ? 201.104 178.445 235.339 1.00 55.30  ? 219 CYS J O     1 
ATOM   1662 C CB    . CYS A 1 213 ? 200.029 181.215 236.617 1.00 55.30  ? 219 CYS J CB    1 
ATOM   1663 S SG    . CYS A 1 213 ? 199.292 182.318 237.834 1.00 55.30  ? 219 CYS J SG    1 
ATOM   1664 N N     . TYR A 1 214 ? 198.929 178.785 234.848 1.00 54.53  ? 220 TYR J N     1 
ATOM   1665 C CA    . TYR A 1 214 ? 198.967 178.062 233.586 1.00 54.53  ? 220 TYR J CA    1 
ATOM   1666 C C     . TYR A 1 214 ? 197.848 178.566 232.688 1.00 54.53  ? 220 TYR J C     1 
ATOM   1667 O O     . TYR A 1 214 ? 196.866 179.139 233.158 1.00 54.53  ? 220 TYR J O     1 
ATOM   1668 C CB    . TYR A 1 214 ? 198.836 176.553 233.794 1.00 54.53  ? 220 TYR J CB    1 
ATOM   1669 C CG    . TYR A 1 214 ? 197.431 176.093 234.087 1.00 54.53  ? 220 TYR J CG    1 
ATOM   1670 C CD1   . TYR A 1 214 ? 196.824 176.381 235.295 1.00 54.53  ? 220 TYR J CD1   1 
ATOM   1671 C CD2   . TYR A 1 214 ? 196.715 175.363 233.157 1.00 54.53  ? 220 TYR J CD2   1 
ATOM   1672 C CE1   . TYR A 1 214 ? 195.546 175.959 235.566 1.00 54.53  ? 220 TYR J CE1   1 
ATOM   1673 C CE2   . TYR A 1 214 ? 195.437 174.938 233.420 1.00 54.53  ? 220 TYR J CE2   1 
ATOM   1674 C CZ    . TYR A 1 214 ? 194.857 175.238 234.626 1.00 54.53  ? 220 TYR J CZ    1 
ATOM   1675 O OH    . TYR A 1 214 ? 193.579 174.815 234.891 1.00 54.53  ? 220 TYR J OH    1 
ATOM   1676 N N     . VAL A 1 215 ? 197.999 178.330 231.387 1.00 55.86  ? 221 VAL J N     1 
ATOM   1677 C CA    . VAL A 1 215 ? 197.071 178.830 230.377 1.00 55.86  ? 221 VAL J CA    1 
ATOM   1678 C C     . VAL A 1 215 ? 196.046 177.750 230.067 1.00 55.86  ? 221 VAL J C     1 
ATOM   1679 O O     . VAL A 1 215 ? 196.406 176.611 229.746 1.00 55.86  ? 221 VAL J O     1 
ATOM   1680 C CB    . VAL A 1 215 ? 197.814 179.260 229.103 1.00 55.86  ? 221 VAL J CB    1 
ATOM   1681 C CG1   . VAL A 1 215 ? 196.867 179.292 227.927 1.00 55.86  ? 221 VAL J CG1   1 
ATOM   1682 C CG2   . VAL A 1 215 ? 198.445 180.618 229.296 1.00 55.86  ? 221 VAL J CG2   1 
ATOM   1683 N N     . ALA A 1 216 ? 194.767 178.105 230.159 1.00 61.34  ? 222 ALA J N     1 
ATOM   1684 C CA    . ALA A 1 216 ? 193.694 177.162 229.883 1.00 61.34  ? 222 ALA J CA    1 
ATOM   1685 C C     . ALA A 1 216 ? 193.447 177.077 228.385 1.00 61.34  ? 222 ALA J C     1 
ATOM   1686 O O     . ALA A 1 216 ? 193.390 178.102 227.700 1.00 61.34  ? 222 ALA J O     1 
ATOM   1687 C CB    . ALA A 1 216 ? 192.418 177.583 230.603 1.00 61.34  ? 222 ALA J CB    1 
ATOM   1688 N N     . LEU A 1 217 ? 193.297 175.852 227.878 1.00 64.37  ? 223 LEU J N     1 
ATOM   1689 C CA    . LEU A 1 217 ? 193.089 175.659 226.446 1.00 64.37  ? 223 LEU J CA    1 
ATOM   1690 C C     . LEU A 1 217 ? 191.784 176.296 225.989 1.00 64.37  ? 223 LEU J C     1 
ATOM   1691 O O     . LEU A 1 217 ? 191.758 177.068 225.024 1.00 64.37  ? 223 LEU J O     1 
ATOM   1692 C CB    . LEU A 1 217 ? 193.106 174.171 226.113 1.00 64.37  ? 223 LEU J CB    1 
ATOM   1693 C CG    . LEU A 1 217 ? 192.809 173.838 224.655 1.00 64.37  ? 223 LEU J CG    1 
ATOM   1694 C CD1   . LEU A 1 217 ? 193.951 174.288 223.770 1.00 64.37  ? 223 LEU J CD1   1 
ATOM   1695 C CD2   . LEU A 1 217 ? 192.553 172.353 224.489 1.00 64.37  ? 223 LEU J CD2   1 
ATOM   1696 N N     . ASP A 1 218 ? 190.686 175.978 226.668 1.00 71.09  ? 224 ASP J N     1 
ATOM   1697 C CA    . ASP A 1 218 ? 189.385 176.581 226.409 1.00 71.09  ? 224 ASP J CA    1 
ATOM   1698 C C     . ASP A 1 218 ? 188.911 177.233 227.696 1.00 71.09  ? 224 ASP J C     1 
ATOM   1699 O O     . ASP A 1 218 ? 188.668 176.544 228.689 1.00 71.09  ? 224 ASP J O     1 
ATOM   1700 C CB    . ASP A 1 218 ? 188.386 175.535 225.910 1.00 71.09  ? 224 ASP J CB    1 
ATOM   1701 C CG    . ASP A 1 218 ? 188.572 174.188 226.581 1.00 71.09  ? 224 ASP J CG    1 
ATOM   1702 O OD1   . ASP A 1 218 ? 189.374 174.102 227.533 1.00 71.09  ? 224 ASP J OD1   1 
ATOM   1703 O OD2   . ASP A 1 218 ? 187.920 173.212 226.153 1.00 71.09  ? 224 ASP J OD2   1 
ATOM   1704 N N     . PHE A 1 219 ? 188.783 178.560 227.677 1.00 66.13  ? 225 PHE J N     1 
ATOM   1705 C CA    . PHE A 1 219 ? 188.698 179.310 228.925 1.00 66.13  ? 225 PHE J CA    1 
ATOM   1706 C C     . PHE A 1 219 ? 187.351 179.131 229.616 1.00 66.13  ? 225 PHE J C     1 
ATOM   1707 O O     . PHE A 1 219 ? 187.293 179.032 230.845 1.00 66.13  ? 225 PHE J O     1 
ATOM   1708 C CB    . PHE A 1 219 ? 188.970 180.788 228.658 1.00 66.13  ? 225 PHE J CB    1 
ATOM   1709 C CG    . PHE A 1 219 ? 189.004 181.630 229.895 1.00 66.13  ? 225 PHE J CG    1 
ATOM   1710 C CD1   . PHE A 1 219 ? 189.998 181.457 230.834 1.00 66.13  ? 225 PHE J CD1   1 
ATOM   1711 C CD2   . PHE A 1 219 ? 188.047 182.599 230.116 1.00 66.13  ? 225 PHE J CD2   1 
ATOM   1712 C CE1   . PHE A 1 219 ? 190.033 182.229 231.970 1.00 66.13  ? 225 PHE J CE1   1 
ATOM   1713 C CE2   . PHE A 1 219 ? 188.080 183.376 231.252 1.00 66.13  ? 225 PHE J CE2   1 
ATOM   1714 C CZ    . PHE A 1 219 ? 189.074 183.190 232.179 1.00 66.13  ? 225 PHE J CZ    1 
ATOM   1715 N N     . GLU A 1 220 ? 186.259 179.080 228.853 1.00 74.02  ? 226 GLU J N     1 
ATOM   1716 C CA    . GLU A 1 220 ? 184.934 179.143 229.465 1.00 74.02  ? 226 GLU J CA    1 
ATOM   1717 C C     . GLU A 1 220 ? 184.578 177.844 230.179 1.00 74.02  ? 226 GLU J C     1 
ATOM   1718 O O     . GLU A 1 220 ? 184.178 177.857 231.349 1.00 74.02  ? 226 GLU J O     1 
ATOM   1719 C CB    . GLU A 1 220 ? 183.886 179.484 228.408 1.00 74.02  ? 226 GLU J CB    1 
ATOM   1720 C CG    . GLU A 1 220 ? 183.981 180.907 227.889 1.00 74.02  ? 226 GLU J CG    1 
ATOM   1721 C CD    . GLU A 1 220 ? 183.729 181.947 228.965 1.00 74.02  ? 226 GLU J CD    1 
ATOM   1722 O OE1   . GLU A 1 220 ? 183.087 181.618 229.984 1.00 74.02  ? 226 GLU J OE1   1 
ATOM   1723 O OE2   . GLU A 1 220 ? 184.177 183.100 228.791 1.00 74.02  ? 226 GLU J OE2   1 
ATOM   1724 N N     . ASN A 1 221 ? 184.703 176.708 229.494 1.00 74.49  ? 227 ASN J N     1 
ATOM   1725 C CA    . ASN A 1 221 ? 184.379 175.449 230.155 1.00 74.49  ? 227 ASN J CA    1 
ATOM   1726 C C     . ASN A 1 221 ? 185.401 175.107 231.229 1.00 74.49  ? 227 ASN J C     1 
ATOM   1727 O O     . ASN A 1 221 ? 185.069 174.412 232.193 1.00 74.49  ? 227 ASN J O     1 
ATOM   1728 C CB    . ASN A 1 221 ? 184.271 174.321 229.133 1.00 74.49  ? 227 ASN J CB    1 
ATOM   1729 C CG    . ASN A 1 221 ? 185.441 174.287 228.196 1.00 74.49  ? 227 ASN J CG    1 
ATOM   1730 O OD1   . ASN A 1 221 ? 186.396 175.037 228.364 1.00 74.49  ? 227 ASN J OD1   1 
ATOM   1731 N ND2   . ASN A 1 221 ? 185.378 173.418 227.196 1.00 74.49  ? 227 ASN J ND2   1 
ATOM   1732 N N     . GLU A 1 222 ? 186.634 175.602 231.102 1.00 72.35  ? 228 GLU J N     1 
ATOM   1733 C CA    . GLU A 1 222 ? 187.595 175.455 232.190 1.00 72.35  ? 228 GLU J CA    1 
ATOM   1734 C C     . GLU A 1 222 ? 187.155 176.245 233.415 1.00 72.35  ? 228 GLU J C     1 
ATOM   1735 O O     . GLU A 1 222 ? 187.254 175.757 234.545 1.00 72.35  ? 228 GLU J O     1 
ATOM   1736 C CB    . GLU A 1 222 ? 188.981 175.905 231.739 1.00 72.35  ? 228 GLU J CB    1 
ATOM   1737 C CG    . GLU A 1 222 ? 190.092 175.517 232.690 1.00 72.35  ? 228 GLU J CG    1 
ATOM   1738 C CD    . GLU A 1 222 ? 190.713 174.185 232.336 1.00 72.35  ? 228 GLU J CD    1 
ATOM   1739 O OE1   . GLU A 1 222 ? 190.811 173.876 231.131 1.00 72.35  ? 228 GLU J OE1   1 
ATOM   1740 O OE2   . GLU A 1 222 ? 191.099 173.442 233.261 1.00 72.35  ? 228 GLU J OE2   1 
ATOM   1741 N N     . MET A 1 223 ? 186.683 177.475 233.208 1.00 71.11  ? 229 MET J N     1 
ATOM   1742 C CA    . MET A 1 223 ? 186.118 178.253 234.303 1.00 71.11  ? 229 MET J CA    1 
ATOM   1743 C C     . MET A 1 223 ? 184.945 177.523 234.941 1.00 71.11  ? 229 MET J C     1 
ATOM   1744 O O     . MET A 1 223 ? 184.798 177.511 236.168 1.00 71.11  ? 229 MET J O     1 
ATOM   1745 C CB    . MET A 1 223 ? 185.681 179.620 233.786 1.00 71.11  ? 229 MET J CB    1 
ATOM   1746 C CG    . MET A 1 223 ? 185.506 180.670 234.850 1.00 71.11  ? 229 MET J CG    1 
ATOM   1747 S SD    . MET A 1 223 ? 187.052 181.460 235.310 1.00 71.11  ? 229 MET J SD    1 
ATOM   1748 C CE    . MET A 1 223 ? 186.435 183.032 235.895 1.00 71.11  ? 229 MET J CE    1 
ATOM   1749 N N     . ALA A 1 224 ? 184.103 176.896 234.118 1.00 73.99  ? 230 ALA J N     1 
ATOM   1750 C CA    . ALA A 1 224 ? 182.963 176.157 234.651 1.00 73.99  ? 230 ALA J CA    1 
ATOM   1751 C C     . ALA A 1 224 ? 183.416 174.952 235.468 1.00 73.99  ? 230 ALA J C     1 
ATOM   1752 O O     . ALA A 1 224 ? 182.851 174.663 236.529 1.00 73.99  ? 230 ALA J O     1 
ATOM   1753 C CB    . ALA A 1 224 ? 182.045 175.718 233.514 1.00 73.99  ? 230 ALA J CB    1 
ATOM   1754 N N     . THR A 1 225 ? 184.433 174.234 234.988 1.00 76.11  ? 231 THR J N     1 
ATOM   1755 C CA    . THR A 1 225 ? 184.950 173.091 235.732 1.00 76.11  ? 231 THR J CA    1 
ATOM   1756 C C     . THR A 1 225 ? 185.571 173.529 237.051 1.00 76.11  ? 231 THR J C     1 
ATOM   1757 O O     . THR A 1 225 ? 185.414 172.855 238.076 1.00 76.11  ? 231 THR J O     1 
ATOM   1758 C CB    . THR A 1 225 ? 185.968 172.328 234.885 1.00 76.11  ? 231 THR J CB    1 
ATOM   1759 O OG1   . THR A 1 225 ? 185.326 171.815 233.711 1.00 76.11  ? 231 THR J OG1   1 
ATOM   1760 C CG2   . THR A 1 225 ? 186.566 171.175 235.670 1.00 76.11  ? 231 THR J CG2   1 
ATOM   1761 N N     . ALA A 1 226 ? 186.279 174.659 237.047 1.00 76.63  ? 232 ALA J N     1 
ATOM   1762 C CA    . ALA A 1 226 ? 186.804 175.202 238.295 1.00 76.63  ? 232 ALA J CA    1 
ATOM   1763 C C     . ALA A 1 226 ? 185.678 175.569 239.250 1.00 76.63  ? 232 ALA J C     1 
ATOM   1764 O O     . ALA A 1 226 ? 185.789 175.361 240.463 1.00 76.63  ? 232 ALA J O     1 
ATOM   1765 C CB    . ALA A 1 226 ? 187.678 176.421 238.014 1.00 76.63  ? 232 ALA J CB    1 
ATOM   1766 N N     . ALA A 1 227 ? 184.585 176.120 238.719 1.00 79.27  ? 233 ALA J N     1 
ATOM   1767 C CA    . ALA A 1 227 ? 183.463 176.506 239.567 1.00 79.27  ? 233 ALA J CA    1 
ATOM   1768 C C     . ALA A 1 227 ? 182.722 175.296 240.120 1.00 79.27  ? 233 ALA J C     1 
ATOM   1769 O O     . ALA A 1 227 ? 182.132 175.377 241.203 1.00 79.27  ? 233 ALA J O     1 
ATOM   1770 C CB    . ALA A 1 227 ? 182.500 177.404 238.791 1.00 79.27  ? 233 ALA J CB    1 
ATOM   1771 N N     . SER A 1 228 ? 182.731 174.175 239.400 1.00 79.66  ? 234 SER J N     1 
ATOM   1772 C CA    . SER A 1 228 ? 181.999 172.995 239.863 1.00 79.66  ? 234 SER J CA    1 
ATOM   1773 C C     . SER A 1 228 ? 182.741 172.290 240.994 1.00 79.66  ? 234 SER J C     1 
ATOM   1774 O O     . SER A 1 228 ? 182.247 172.203 242.122 1.00 79.66  ? 234 SER J O     1 
ATOM   1775 C CB    . SER A 1 228 ? 181.763 172.033 238.695 1.00 79.66  ? 234 SER J CB    1 
ATOM   1776 O OG    . SER A 1 228 ? 182.986 171.468 238.254 1.00 79.66  ? 234 SER J OG    1 
ATOM   1777 N N     . SER A 1 229 ? 183.930 171.782 240.703 1.00 80.53  ? 235 SER J N     1 
ATOM   1778 C CA    . SER A 1 229 ? 184.721 171.018 241.649 1.00 80.53  ? 235 SER J CA    1 
ATOM   1779 C C     . SER A 1 229 ? 185.700 171.930 242.382 1.00 80.53  ? 235 SER J C     1 
ATOM   1780 O O     . SER A 1 229 ? 185.621 173.160 242.311 1.00 80.53  ? 235 SER J O     1 
ATOM   1781 C CB    . SER A 1 229 ? 185.452 169.887 240.925 1.00 80.53  ? 235 SER J CB    1 
ATOM   1782 O OG    . SER A 1 229 ? 186.292 169.173 241.815 1.00 80.53  ? 235 SER J OG    1 
ATOM   1783 N N     . SER A 1 230 ? 186.631 171.315 243.110 1.00 77.96  ? 236 SER J N     1 
ATOM   1784 C CA    . SER A 1 230 ? 187.762 172.007 243.711 1.00 77.96  ? 236 SER J CA    1 
ATOM   1785 C C     . SER A 1 230 ? 189.066 171.333 243.308 1.00 77.96  ? 236 SER J C     1 
ATOM   1786 O O     . SER A 1 230 ? 190.054 171.384 244.043 1.00 77.96  ? 236 SER J O     1 
ATOM   1787 C CB    . SER A 1 230 ? 187.636 172.056 245.232 1.00 77.96  ? 236 SER J CB    1 
ATOM   1788 O OG    . SER A 1 230 ? 188.203 170.899 245.819 1.00 77.96  ? 236 SER J OG    1 
ATOM   1789 N N     . SER A 1 231 ? 189.075 170.691 242.140 1.00 74.91  ? 237 SER J N     1 
ATOM   1790 C CA    . SER A 1 231 ? 190.235 169.945 241.672 1.00 74.91  ? 237 SER J CA    1 
ATOM   1791 C C     . SER A 1 231 ? 191.305 170.832 241.054 1.00 74.91  ? 237 SER J C     1 
ATOM   1792 O O     . SER A 1 231 ? 192.407 170.345 240.783 1.00 74.91  ? 237 SER J O     1 
ATOM   1793 C CB    . SER A 1 231 ? 189.797 168.887 240.660 1.00 74.91  ? 237 SER J CB    1 
ATOM   1794 O OG    . SER A 1 231 ? 189.252 169.494 239.502 1.00 74.91  ? 237 SER J OG    1 
ATOM   1795 N N     . LEU A 1 232 ? 191.010 172.107 240.820 1.00 71.31  ? 238 LEU J N     1 
ATOM   1796 C CA    . LEU A 1 232 ? 192.005 173.059 240.351 1.00 71.31  ? 238 LEU J CA    1 
ATOM   1797 C C     . LEU A 1 232 ? 192.630 173.856 241.484 1.00 71.31  ? 238 LEU J C     1 
ATOM   1798 O O     . LEU A 1 232 ? 193.329 174.839 241.220 1.00 71.31  ? 238 LEU J O     1 
ATOM   1799 C CB    . LEU A 1 232 ? 191.385 174.014 239.332 1.00 71.31  ? 238 LEU J CB    1 
ATOM   1800 C CG    . LEU A 1 232 ? 190.925 173.348 238.038 1.00 71.31  ? 238 LEU J CG    1 
ATOM   1801 C CD1   . LEU A 1 232 ? 190.480 174.385 237.030 1.00 71.31  ? 238 LEU J CD1   1 
ATOM   1802 C CD2   . LEU A 1 232 ? 192.036 172.485 237.466 1.00 71.31  ? 238 LEU J CD2   1 
ATOM   1803 N N     . GLU A 1 233 ? 192.392 173.462 242.732 1.00 69.56  ? 239 GLU J N     1 
ATOM   1804 C CA    . GLU A 1 233 ? 192.960 174.160 243.874 1.00 69.56  ? 239 GLU J CA    1 
ATOM   1805 C C     . GLU A 1 233 ? 194.352 173.625 244.177 1.00 69.56  ? 239 GLU J C     1 
ATOM   1806 O O     . GLU A 1 233 ? 194.566 172.411 244.211 1.00 69.56  ? 239 GLU J O     1 
ATOM   1807 C CB    . GLU A 1 233 ? 192.057 174.001 245.094 1.00 69.56  ? 239 GLU J CB    1 
ATOM   1808 C CG    . GLU A 1 233 ? 190.830 174.887 245.076 1.00 69.56  ? 239 GLU J CG    1 
ATOM   1809 C CD    . GLU A 1 233 ? 190.323 175.193 246.467 1.00 69.56  ? 239 GLU J CD    1 
ATOM   1810 O OE1   . GLU A 1 233 ? 190.770 174.526 247.422 1.00 69.56  ? 239 GLU J OE1   1 
ATOM   1811 O OE2   . GLU A 1 233 ? 189.480 176.102 246.607 1.00 69.56  ? 239 GLU J OE2   1 
ATOM   1812 N N     . LYS A 1 234 ? 195.297 174.534 244.391 1.00 63.45  ? 240 LYS J N     1 
ATOM   1813 C CA    . LYS A 1 234 ? 196.646 174.179 244.797 1.00 63.45  ? 240 LYS J CA    1 
ATOM   1814 C C     . LYS A 1 234 ? 197.115 175.158 245.861 1.00 63.45  ? 240 LYS J C     1 
ATOM   1815 O O     . LYS A 1 234 ? 196.715 176.323 245.881 1.00 63.45  ? 240 LYS J O     1 
ATOM   1816 C CB    . LYS A 1 234 ? 197.619 174.174 243.613 1.00 63.45  ? 240 LYS J CB    1 
ATOM   1817 C CG    . LYS A 1 234 ? 197.382 173.041 242.634 1.00 63.45  ? 240 LYS J CG    1 
ATOM   1818 C CD    . LYS A 1 234 ? 198.560 172.868 241.696 1.00 63.45  ? 240 LYS J CD    1 
ATOM   1819 C CE    . LYS A 1 234 ? 199.724 172.214 242.404 1.00 63.45  ? 240 LYS J CE    1 
ATOM   1820 N NZ    . LYS A 1 234 ? 199.318 170.917 243.001 1.00 63.45  ? 240 LYS J NZ    1 
ATOM   1821 N N     . SER A 1 235 ? 197.979 174.672 246.746 1.00 63.20  ? 241 SER J N     1 
ATOM   1822 C CA    . SER A 1 235 ? 198.395 175.414 247.925 1.00 63.20  ? 241 SER J CA    1 
ATOM   1823 C C     . SER A 1 235 ? 199.827 175.904 247.772 1.00 63.20  ? 241 SER J C     1 
ATOM   1824 O O     . SER A 1 235 ? 200.708 175.156 247.340 1.00 63.20  ? 241 SER J O     1 
ATOM   1825 C CB    . SER A 1 235 ? 198.277 174.551 249.181 1.00 63.20  ? 241 SER J CB    1 
ATOM   1826 O OG    . SER A 1 235 ? 197.047 173.850 249.202 1.00 63.20  ? 241 SER J OG    1 
ATOM   1827 N N     . TYR A 1 236 ? 200.051 177.161 248.138 1.00 63.15  ? 242 TYR J N     1 
ATOM   1828 C CA    . TYR A 1 236 ? 201.370 177.769 248.123 1.00 63.15  ? 242 TYR J CA    1 
ATOM   1829 C C     . TYR A 1 236 ? 201.677 178.293 249.517 1.00 63.15  ? 242 TYR J C     1 
ATOM   1830 O O     . TYR A 1 236 ? 200.773 178.672 250.263 1.00 63.15  ? 242 TYR J O     1 
ATOM   1831 C CB    . TYR A 1 236 ? 201.449 178.899 247.092 1.00 63.15  ? 242 TYR J CB    1 
ATOM   1832 C CG    . TYR A 1 236 ? 202.772 179.624 247.047 1.00 63.15  ? 242 TYR J CG    1 
ATOM   1833 C CD1   . TYR A 1 236 ? 203.820 179.148 246.275 1.00 63.15  ? 242 TYR J CD1   1 
ATOM   1834 C CD2   . TYR A 1 236 ? 202.968 180.793 247.765 1.00 63.15  ? 242 TYR J CD2   1 
ATOM   1835 C CE1   . TYR A 1 236 ? 205.028 179.812 246.227 1.00 63.15  ? 242 TYR J CE1   1 
ATOM   1836 C CE2   . TYR A 1 236 ? 204.173 181.462 247.724 1.00 63.15  ? 242 TYR J CE2   1 
ATOM   1837 C CZ    . TYR A 1 236 ? 205.197 180.969 246.953 1.00 63.15  ? 242 TYR J CZ    1 
ATOM   1838 O OH    . TYR A 1 236 ? 206.394 181.639 246.912 1.00 63.15  ? 242 TYR J OH    1 
ATOM   1839 N N     . GLU A 1 237 ? 202.960 178.308 249.867 1.00 67.58  ? 243 GLU J N     1 
ATOM   1840 C CA    . GLU A 1 237 ? 203.402 178.669 251.210 1.00 67.58  ? 243 GLU J CA    1 
ATOM   1841 C C     . GLU A 1 237 ? 204.251 179.930 251.141 1.00 67.58  ? 243 GLU J C     1 
ATOM   1842 O O     . GLU A 1 237 ? 205.355 179.912 250.589 1.00 67.58  ? 243 GLU J O     1 
ATOM   1843 C CB    . GLU A 1 237 ? 204.181 177.525 251.851 1.00 67.58  ? 243 GLU J CB    1 
ATOM   1844 C CG    . GLU A 1 237 ? 204.874 177.908 253.138 1.00 67.58  ? 243 GLU J CG    1 
ATOM   1845 C CD    . GLU A 1 237 ? 205.154 176.713 254.020 1.00 67.58  ? 243 GLU J CD    1 
ATOM   1846 O OE1   . GLU A 1 237 ? 204.503 175.666 253.825 1.00 67.58  ? 243 GLU J OE1   1 
ATOM   1847 O OE2   . GLU A 1 237 ? 206.024 176.818 254.910 1.00 67.58  ? 243 GLU J OE2   1 
ATOM   1848 N N     . LEU A 1 238 ? 203.732 181.021 251.704 1.00 65.03  ? 244 LEU J N     1 
ATOM   1849 C CA    . LEU A 1 238 ? 204.491 182.251 251.818 1.00 65.03  ? 244 LEU J CA    1 
ATOM   1850 C C     . LEU A 1 238 ? 205.695 182.031 252.734 1.00 65.03  ? 244 LEU J C     1 
ATOM   1851 O O     . LEU A 1 238 ? 205.754 181.038 253.461 1.00 65.03  ? 244 LEU J O     1 
ATOM   1852 C CB    . LEU A 1 238 ? 203.592 183.358 252.357 1.00 65.03  ? 244 LEU J CB    1 
ATOM   1853 C CG    . LEU A 1 238 ? 202.288 183.516 251.583 1.00 65.03  ? 244 LEU J CG    1 
ATOM   1854 C CD1   . LEU A 1 238 ? 201.319 184.386 252.348 1.00 65.03  ? 244 LEU J CD1   1 
ATOM   1855 C CD2   . LEU A 1 238 ? 202.565 184.100 250.219 1.00 65.03  ? 244 LEU J CD2   1 
ATOM   1856 N N     . PRO A 1 239 ? 206.674 182.940 252.722 1.00 65.54  ? 245 PRO J N     1 
ATOM   1857 C CA    . PRO A 1 239 ? 207.883 182.694 253.520 1.00 65.54  ? 245 PRO J CA    1 
ATOM   1858 C C     . PRO A 1 239 ? 207.745 183.068 254.988 1.00 65.54  ? 245 PRO J C     1 
ATOM   1859 O O     . PRO A 1 239 ? 208.671 183.630 255.577 1.00 65.54  ? 245 PRO J O     1 
ATOM   1860 C CB    . PRO A 1 239 ? 208.930 183.569 252.825 1.00 65.54  ? 245 PRO J CB    1 
ATOM   1861 C CG    . PRO A 1 239 ? 208.146 184.696 252.288 1.00 65.54  ? 245 PRO J CG    1 
ATOM   1862 C CD    . PRO A 1 239 ? 206.845 184.102 251.832 1.00 65.54  ? 245 PRO J CD    1 
ATOM   1863 N N     . ASP A 1 240 ? 206.592 182.773 255.587 1.00 68.40  ? 246 ASP J N     1 
ATOM   1864 C CA    . ASP A 1 240 ? 206.451 182.789 257.037 1.00 68.40  ? 246 ASP J CA    1 
ATOM   1865 C C     . ASP A 1 240 ? 205.525 181.674 257.508 1.00 68.40  ? 246 ASP J C     1 
ATOM   1866 O O     . ASP A 1 240 ? 204.881 181.799 258.554 1.00 68.40  ? 246 ASP J O     1 
ATOM   1867 C CB    . ASP A 1 240 ? 205.948 184.145 257.532 1.00 68.40  ? 246 ASP J CB    1 
ATOM   1868 C CG    . ASP A 1 240 ? 204.477 184.363 257.250 1.00 68.40  ? 246 ASP J CG    1 
ATOM   1869 O OD1   . ASP A 1 240 ? 203.964 183.799 256.263 1.00 68.40  ? 246 ASP J OD1   1 
ATOM   1870 O OD2   . ASP A 1 240 ? 203.829 185.097 258.023 1.00 68.40  ? 246 ASP J OD2   1 
ATOM   1871 N N     . GLY A 1 241 ? 205.452 180.577 256.761 1.00 68.14  ? 247 GLY J N     1 
ATOM   1872 C CA    . GLY A 1 241 ? 204.348 179.655 256.927 1.00 68.14  ? 247 GLY J CA    1 
ATOM   1873 C C     . GLY A 1 241 ? 203.143 180.269 256.254 1.00 68.14  ? 247 GLY J C     1 
ATOM   1874 O O     . GLY A 1 241 ? 203.286 180.876 255.191 1.00 68.14  ? 247 GLY J O     1 
ATOM   1875 N N     . GLN A 1 242 ? 201.960 180.141 256.852 1.00 68.85  ? 248 GLN J N     1 
ATOM   1876 C CA    . GLN A 1 242 ? 200.770 180.852 256.387 1.00 68.85  ? 248 GLN J CA    1 
ATOM   1877 C C     . GLN A 1 242 ? 200.473 180.522 254.922 1.00 68.85  ? 248 GLN J C     1 
ATOM   1878 O O     . GLN A 1 242 ? 200.559 181.369 254.032 1.00 68.85  ? 248 GLN J O     1 
ATOM   1879 C CB    . GLN A 1 242 ? 200.928 182.362 256.597 1.00 68.85  ? 248 GLN J CB    1 
ATOM   1880 C CG    . GLN A 1 242 ? 199.666 183.168 256.353 1.00 68.85  ? 248 GLN J CG    1 
ATOM   1881 C CD    . GLN A 1 242 ? 199.734 184.552 256.962 1.00 68.85  ? 248 GLN J CD    1 
ATOM   1882 O OE1   . GLN A 1 242 ? 200.155 185.507 256.312 1.00 68.85  ? 248 GLN J OE1   1 
ATOM   1883 N NE2   . GLN A 1 242 ? 199.315 184.668 258.216 1.00 68.85  ? 248 GLN J NE2   1 
ATOM   1884 N N     . VAL A 1 243 ? 200.149 179.251 254.682 1.00 65.11  ? 249 VAL J N     1 
ATOM   1885 C CA    . VAL A 1 243 ? 199.921 178.793 253.320 1.00 65.11  ? 249 VAL J CA    1 
ATOM   1886 C C     . VAL A 1 243 ? 198.652 179.426 252.763 1.00 65.11  ? 249 VAL J C     1 
ATOM   1887 O O     . VAL A 1 243 ? 197.731 179.796 253.502 1.00 65.11  ? 249 VAL J O     1 
ATOM   1888 C CB    . VAL A 1 243 ? 199.837 177.258 253.267 1.00 65.11  ? 249 VAL J CB    1 
ATOM   1889 C CG1   . VAL A 1 243 ? 201.121 176.642 253.784 1.00 65.11  ? 249 VAL J CG1   1 
ATOM   1890 C CG2   . VAL A 1 243 ? 198.640 176.763 254.055 1.00 65.11  ? 249 VAL J CG2   1 
ATOM   1891 N N     . ILE A 1 244 ? 198.609 179.559 251.440 1.00 63.20  ? 250 ILE J N     1 
ATOM   1892 C CA    . ILE A 1 244 ? 197.440 180.057 250.730 1.00 63.20  ? 250 ILE J CA    1 
ATOM   1893 C C     . ILE A 1 244 ? 197.057 179.033 249.674 1.00 63.20  ? 250 ILE J C     1 
ATOM   1894 O O     . ILE A 1 244 ? 197.887 178.236 249.227 1.00 63.20  ? 250 ILE J O     1 
ATOM   1895 C CB    . ILE A 1 244 ? 197.690 181.438 250.085 1.00 63.20  ? 250 ILE J CB    1 
ATOM   1896 C CG1   . ILE A 1 244 ? 198.547 181.294 248.829 1.00 63.20  ? 250 ILE J CG1   1 
ATOM   1897 C CG2   . ILE A 1 244 ? 198.362 182.371 251.070 1.00 63.20  ? 250 ILE J CG2   1 
ATOM   1898 C CD1   . ILE A 1 244 ? 198.997 182.604 248.249 1.00 63.20  ? 250 ILE J CD1   1 
ATOM   1899 N N     . THR A 1 245 ? 195.786 179.045 249.286 1.00 62.04  ? 251 THR J N     1 
ATOM   1900 C CA    . THR A 1 245 ? 195.274 178.176 248.236 1.00 62.04  ? 251 THR J CA    1 
ATOM   1901 C C     . THR A 1 245 ? 194.564 179.028 247.197 1.00 62.04  ? 251 THR J C     1 
ATOM   1902 O O     . THR A 1 245 ? 193.762 179.898 247.549 1.00 62.04  ? 251 THR J O     1 
ATOM   1903 C CB    . THR A 1 245 ? 194.312 177.125 248.792 1.00 62.04  ? 251 THR J CB    1 
ATOM   1904 O OG1   . THR A 1 245 ? 193.050 177.736 249.077 1.00 62.04  ? 251 THR J OG1   1 
ATOM   1905 C CG2   . THR A 1 245 ? 194.865 176.513 250.061 1.00 62.04  ? 251 THR J CG2   1 
ATOM   1906 N N     . ILE A 1 246 ? 194.859 178.783 245.925 1.00 59.35  ? 252 ILE J N     1 
ATOM   1907 C CA    . ILE A 1 246 ? 194.236 179.520 244.837 1.00 59.35  ? 252 ILE J CA    1 
ATOM   1908 C C     . ILE A 1 246 ? 193.505 178.544 243.931 1.00 59.35  ? 252 ILE J C     1 
ATOM   1909 O O     . ILE A 1 246 ? 193.890 177.380 243.793 1.00 59.35  ? 252 ILE J O     1 
ATOM   1910 C CB    . ILE A 1 246 ? 195.256 180.348 244.035 1.00 59.35  ? 252 ILE J CB    1 
ATOM   1911 C CG1   . ILE A 1 246 ? 196.457 179.495 243.647 1.00 59.35  ? 252 ILE J CG1   1 
ATOM   1912 C CG2   . ILE A 1 246 ? 195.722 181.526 244.849 1.00 59.35  ? 252 ILE J CG2   1 
ATOM   1913 C CD1   . ILE A 1 246 ? 197.527 180.277 242.927 1.00 59.35  ? 252 ILE J CD1   1 
ATOM   1914 N N     . GLY A 1 247 ? 192.439 179.034 243.310 1.00 59.76  ? 253 GLY J N     1 
ATOM   1915 C CA    . GLY A 1 247 ? 191.610 178.216 242.453 1.00 59.76  ? 253 GLY J CA    1 
ATOM   1916 C C     . GLY A 1 247 ? 191.717 178.600 240.995 1.00 59.76  ? 253 GLY J C     1 
ATOM   1917 O O     . GLY A 1 247 ? 192.667 178.213 240.311 1.00 59.76  ? 253 GLY J O     1 
ATOM   1918 N N     . ASN A 1 248 ? 190.740 179.358 240.503 1.00 60.21  ? 254 ASN J N     1 
ATOM   1919 C CA    . ASN A 1 248 ? 190.724 179.733 239.098 1.00 60.21  ? 254 ASN J CA    1 
ATOM   1920 C C     . ASN A 1 248 ? 191.665 180.884 238.772 1.00 60.21  ? 254 ASN J C     1 
ATOM   1921 O O     . ASN A 1 248 ? 191.851 181.185 237.588 1.00 60.21  ? 254 ASN J O     1 
ATOM   1922 C CB    . ASN A 1 248 ? 189.299 180.081 238.661 1.00 60.21  ? 254 ASN J CB    1 
ATOM   1923 C CG    . ASN A 1 248 ? 188.778 181.351 239.298 1.00 60.21  ? 254 ASN J CG    1 
ATOM   1924 O OD1   . ASN A 1 248 ? 189.434 181.957 240.142 1.00 60.21  ? 254 ASN J OD1   1 
ATOM   1925 N ND2   . ASN A 1 248 ? 187.586 181.761 238.894 1.00 60.21  ? 254 ASN J ND2   1 
ATOM   1926 N N     . GLU A 1 249 ? 192.255 181.536 239.777 1.00 58.95  ? 255 GLU J N     1 
ATOM   1927 C CA    . GLU A 1 249 ? 193.245 182.569 239.490 1.00 58.95  ? 255 GLU J CA    1 
ATOM   1928 C C     . GLU A 1 249 ? 194.408 182.009 238.687 1.00 58.95  ? 255 GLU J C     1 
ATOM   1929 O O     . GLU A 1 249 ? 195.013 182.733 237.886 1.00 58.95  ? 255 GLU J O     1 
ATOM   1930 C CB    . GLU A 1 249 ? 193.752 183.196 240.787 1.00 58.95  ? 255 GLU J CB    1 
ATOM   1931 C CG    . GLU A 1 249 ? 192.787 184.166 241.437 1.00 58.95  ? 255 GLU J CG    1 
ATOM   1932 C CD    . GLU A 1 249 ? 191.789 183.481 242.348 1.00 58.95  ? 255 GLU J CD    1 
ATOM   1933 O OE1   . GLU A 1 249 ? 191.740 182.235 242.350 1.00 58.95  ? 255 GLU J OE1   1 
ATOM   1934 O OE2   . GLU A 1 249 ? 191.054 184.190 243.065 1.00 58.95  ? 255 GLU J OE2   1 
ATOM   1935 N N     . ARG A 1 250 ? 194.705 180.718 238.867 1.00 56.50  ? 256 ARG J N     1 
ATOM   1936 C CA    . ARG A 1 250 ? 195.803 180.072 238.158 1.00 56.50  ? 256 ARG J CA    1 
ATOM   1937 C C     . ARG A 1 250 ? 195.729 180.314 236.659 1.00 56.50  ? 256 ARG J C     1 
ATOM   1938 O O     . ARG A 1 250 ? 196.743 180.614 236.023 1.00 56.50  ? 256 ARG J O     1 
ATOM   1939 C CB    . ARG A 1 250 ? 195.798 178.572 238.442 1.00 56.50  ? 256 ARG J CB    1 
ATOM   1940 C CG    . ARG A 1 250 ? 195.985 178.204 239.889 1.00 56.50  ? 256 ARG J CG    1 
ATOM   1941 C CD    . ARG A 1 250 ? 195.912 176.706 240.057 1.00 56.50  ? 256 ARG J CD    1 
ATOM   1942 N NE    . ARG A 1 250 ? 197.027 176.042 239.397 1.00 56.50  ? 256 ARG J NE    1 
ATOM   1943 C CZ    . ARG A 1 250 ? 197.028 174.761 239.047 1.00 56.50  ? 256 ARG J CZ    1 
ATOM   1944 N NH1   . ARG A 1 250 ? 195.970 174.005 239.292 1.00 56.50  ? 256 ARG J NH1   1 
ATOM   1945 N NH2   . ARG A 1 250 ? 198.087 174.237 238.448 1.00 56.50  ? 256 ARG J NH2   1 
ATOM   1946 N N     . PHE A 1 251 ? 194.544 180.179 236.072 1.00 57.27  ? 257 PHE J N     1 
ATOM   1947 C CA    . PHE A 1 251 ? 194.378 180.404 234.646 1.00 57.27  ? 257 PHE J CA    1 
ATOM   1948 C C     . PHE A 1 251 ? 193.656 181.701 234.321 1.00 57.27  ? 257 PHE J C     1 
ATOM   1949 O O     . PHE A 1 251 ? 193.506 182.027 233.142 1.00 57.27  ? 257 PHE J O     1 
ATOM   1950 C CB    . PHE A 1 251 ? 193.653 179.222 233.995 1.00 57.27  ? 257 PHE J CB    1 
ATOM   1951 C CG    . PHE A 1 251 ? 192.296 178.945 234.559 1.00 57.27  ? 257 PHE J CG    1 
ATOM   1952 C CD1   . PHE A 1 251 ? 191.182 179.591 234.066 1.00 57.27  ? 257 PHE J CD1   1 
ATOM   1953 C CD2   . PHE A 1 251 ? 192.130 178.014 235.560 1.00 57.27  ? 257 PHE J CD2   1 
ATOM   1954 C CE1   . PHE A 1 251 ? 189.939 179.328 234.573 1.00 57.27  ? 257 PHE J CE1   1 
ATOM   1955 C CE2   . PHE A 1 251 ? 190.886 177.749 236.069 1.00 57.27  ? 257 PHE J CE2   1 
ATOM   1956 C CZ    . PHE A 1 251 ? 189.790 178.407 235.574 1.00 57.27  ? 257 PHE J CZ    1 
ATOM   1957 N N     . ARG A 1 252 ? 193.203 182.449 235.325 1.00 56.37  ? 258 ARG J N     1 
ATOM   1958 C CA    . ARG A 1 252 ? 192.710 183.790 235.050 1.00 56.37  ? 258 ARG J CA    1 
ATOM   1959 C C     . ARG A 1 252 ? 193.848 184.784 234.901 1.00 56.37  ? 258 ARG J C     1 
ATOM   1960 O O     . ARG A 1 252 ? 193.686 185.805 234.226 1.00 56.37  ? 258 ARG J O     1 
ATOM   1961 C CB    . ARG A 1 252 ? 191.761 184.256 236.153 1.00 56.37  ? 258 ARG J CB    1 
ATOM   1962 C CG    . ARG A 1 252 ? 190.386 183.642 236.082 1.00 56.37  ? 258 ARG J CG    1 
ATOM   1963 C CD    . ARG A 1 252 ? 189.550 184.029 237.283 1.00 56.37  ? 258 ARG J CD    1 
ATOM   1964 N NE    . ARG A 1 252 ? 189.367 185.471 237.393 1.00 56.37  ? 258 ARG J NE    1 
ATOM   1965 C CZ    . ARG A 1 252 ? 188.872 186.078 238.465 1.00 56.37  ? 258 ARG J CZ    1 
ATOM   1966 N NH1   . ARG A 1 252 ? 188.518 185.368 239.525 1.00 56.37  ? 258 ARG J NH1   1 
ATOM   1967 N NH2   . ARG A 1 252 ? 188.736 187.396 238.481 1.00 56.37  ? 258 ARG J NH2   1 
ATOM   1968 N N     . CYS A 1 253 ? 195.003 184.515 235.525 1.00 56.39  ? 259 CYS J N     1 
ATOM   1969 C CA    . CYS A 1 253 ? 196.129 185.440 235.386 1.00 56.39  ? 259 CYS J CA    1 
ATOM   1970 C C     . CYS A 1 253 ? 196.702 185.443 233.974 1.00 56.39  ? 259 CYS J C     1 
ATOM   1971 O O     . CYS A 1 253 ? 196.749 186.517 233.348 1.00 56.39  ? 259 CYS J O     1 
ATOM   1972 C CB    . CYS A 1 253 ? 197.193 185.139 236.443 1.00 56.39  ? 259 CYS J CB    1 
ATOM   1973 S SG    . CYS A 1 253 ? 198.619 186.229 236.348 1.00 56.39  ? 259 CYS J SG    1 
ATOM   1974 N N     . PRO A 1 254 ? 197.152 184.316 233.408 1.00 55.02  ? 260 PRO J N     1 
ATOM   1975 C CA    . PRO A 1 254 ? 197.778 184.373 232.082 1.00 55.02  ? 260 PRO J CA    1 
ATOM   1976 C C     . PRO A 1 254 ? 196.800 184.558 230.938 1.00 55.02  ? 260 PRO J C     1 
ATOM   1977 O O     . PRO A 1 254 ? 197.239 184.848 229.818 1.00 55.02  ? 260 PRO J O     1 
ATOM   1978 C CB    . PRO A 1 254 ? 198.482 183.020 231.980 1.00 55.02  ? 260 PRO J CB    1 
ATOM   1979 C CG    . PRO A 1 254 ? 197.616 182.133 232.740 1.00 55.02  ? 260 PRO J CG    1 
ATOM   1980 C CD    . PRO A 1 254 ? 197.129 182.931 233.911 1.00 55.02  ? 260 PRO J CD    1 
ATOM   1981 N N     . GLU A 1 255 ? 195.498 184.395 231.175 1.00 56.44  ? 261 GLU J N     1 
ATOM   1982 C CA    . GLU A 1 255 ? 194.511 184.671 230.140 1.00 56.44  ? 261 GLU J CA    1 
ATOM   1983 C C     . GLU A 1 255 ? 194.519 186.134 229.724 1.00 56.44  ? 261 GLU J C     1 
ATOM   1984 O O     . GLU A 1 255 ? 194.020 186.464 228.645 1.00 56.44  ? 261 GLU J O     1 
ATOM   1985 C CB    . GLU A 1 255 ? 193.120 184.268 230.629 1.00 56.44  ? 261 GLU J CB    1 
ATOM   1986 C CG    . GLU A 1 255 ? 192.039 184.319 229.571 1.00 56.44  ? 261 GLU J CG    1 
ATOM   1987 C CD    . GLU A 1 255 ? 192.192 183.231 228.536 1.00 56.44  ? 261 GLU J CD    1 
ATOM   1988 O OE1   . GLU A 1 255 ? 192.930 182.260 228.798 1.00 56.44  ? 261 GLU J OE1   1 
ATOM   1989 O OE2   . GLU A 1 255 ? 191.577 183.346 227.455 1.00 56.44  ? 261 GLU J OE2   1 
ATOM   1990 N N     . THR A 1 256 ? 195.085 187.015 230.550 1.00 55.01  ? 262 THR J N     1 
ATOM   1991 C CA    . THR A 1 256 ? 195.210 188.417 230.174 1.00 55.01  ? 262 THR J CA    1 
ATOM   1992 C C     . THR A 1 256 ? 196.031 188.585 228.902 1.00 55.01  ? 262 THR J C     1 
ATOM   1993 O O     . THR A 1 256 ? 195.875 189.580 228.188 1.00 55.01  ? 262 THR J O     1 
ATOM   1994 C CB    . THR A 1 256 ? 195.835 189.202 231.325 1.00 55.01  ? 262 THR J CB    1 
ATOM   1995 O OG1   . THR A 1 256 ? 195.075 188.977 232.515 1.00 55.01  ? 262 THR J OG1   1 
ATOM   1996 C CG2   . THR A 1 256 ? 195.848 190.685 231.029 1.00 55.01  ? 262 THR J CG2   1 
ATOM   1997 N N     . LEU A 1 257 ? 196.902 187.622 228.595 1.00 54.65  ? 263 LEU J N     1 
ATOM   1998 C CA    . LEU A 1 257 ? 197.672 187.691 227.358 1.00 54.65  ? 263 LEU J CA    1 
ATOM   1999 C C     . LEU A 1 257 ? 196.764 187.594 226.141 1.00 54.65  ? 263 LEU J C     1 
ATOM   2000 O O     . LEU A 1 257 ? 196.952 188.318 225.159 1.00 54.65  ? 263 LEU J O     1 
ATOM   2001 C CB    . LEU A 1 257 ? 198.720 186.581 227.329 1.00 54.65  ? 263 LEU J CB    1 
ATOM   2002 C CG    . LEU A 1 257 ? 199.941 186.749 228.228 1.00 54.65  ? 263 LEU J CG    1 
ATOM   2003 C CD1   . LEU A 1 257 ? 200.777 185.487 228.209 1.00 54.65  ? 263 LEU J CD1   1 
ATOM   2004 C CD2   . LEU A 1 257 ? 200.760 187.941 227.784 1.00 54.65  ? 263 LEU J CD2   1 
ATOM   2005 N N     . PHE A 1 258 ? 195.770 186.709 226.189 1.00 53.38  ? 264 PHE J N     1 
ATOM   2006 C CA    . PHE A 1 258 ? 194.862 186.516 225.069 1.00 53.38  ? 264 PHE J CA    1 
ATOM   2007 C C     . PHE A 1 258 ? 193.605 187.365 225.156 1.00 53.38  ? 264 PHE J C     1 
ATOM   2008 O O     . PHE A 1 258 ? 192.887 187.478 224.159 1.00 53.38  ? 264 PHE J O     1 
ATOM   2009 C CB    . PHE A 1 258 ? 194.458 185.044 224.963 1.00 53.38  ? 264 PHE J CB    1 
ATOM   2010 C CG    . PHE A 1 258 ? 195.618 184.110 224.821 1.00 53.38  ? 264 PHE J CG    1 
ATOM   2011 C CD1   . PHE A 1 258 ? 196.199 183.534 225.931 1.00 53.38  ? 264 PHE J CD1   1 
ATOM   2012 C CD2   . PHE A 1 258 ? 196.128 183.807 223.576 1.00 53.38  ? 264 PHE J CD2   1 
ATOM   2013 C CE1   . PHE A 1 258 ? 197.265 182.676 225.801 1.00 53.38  ? 264 PHE J CE1   1 
ATOM   2014 C CE2   . PHE A 1 258 ? 197.193 182.950 223.443 1.00 53.38  ? 264 PHE J CE2   1 
ATOM   2015 C CZ    . PHE A 1 258 ? 197.762 182.386 224.556 1.00 53.38  ? 264 PHE J CZ    1 
ATOM   2016 N N     . GLN A 1 259 ? 193.319 187.955 226.314 1.00 56.74  ? 265 GLN J N     1 
ATOM   2017 C CA    . GLN A 1 259 ? 192.167 188.836 226.506 1.00 56.74  ? 265 GLN J CA    1 
ATOM   2018 C C     . GLN A 1 259 ? 192.613 190.081 227.257 1.00 56.74  ? 265 GLN J C     1 
ATOM   2019 O O     . GLN A 1 259 ? 192.262 190.277 228.425 1.00 56.74  ? 265 GLN J O     1 
ATOM   2020 C CB    . GLN A 1 259 ? 191.044 188.126 227.262 1.00 56.74  ? 265 GLN J CB    1 
ATOM   2021 C CG    . GLN A 1 259 ? 190.453 186.944 226.539 1.00 56.74  ? 265 GLN J CG    1 
ATOM   2022 C CD    . GLN A 1 259 ? 189.216 186.424 227.225 1.00 56.74  ? 265 GLN J CD    1 
ATOM   2023 O OE1   . GLN A 1 259 ? 188.524 187.165 227.918 1.00 56.74  ? 265 GLN J OE1   1 
ATOM   2024 N NE2   . GLN A 1 259 ? 188.931 185.141 227.043 1.00 56.74  ? 265 GLN J NE2   1 
ATOM   2025 N N     . PRO A 1 260 ? 193.383 190.957 226.608 1.00 57.55  ? 266 PRO J N     1 
ATOM   2026 C CA    . PRO A 1 260 ? 193.921 192.126 227.313 1.00 57.55  ? 266 PRO J CA    1 
ATOM   2027 C C     . PRO A 1 260 ? 192.867 193.115 227.775 1.00 57.55  ? 266 PRO J C     1 
ATOM   2028 O O     . PRO A 1 260 ? 193.230 194.155 228.332 1.00 57.55  ? 266 PRO J O     1 
ATOM   2029 C CB    . PRO A 1 260 ? 194.853 192.760 226.274 1.00 57.55  ? 266 PRO J CB    1 
ATOM   2030 C CG    . PRO A 1 260 ? 194.344 192.292 224.983 1.00 57.55  ? 266 PRO J CG    1 
ATOM   2031 C CD    . PRO A 1 260 ? 193.803 190.922 225.202 1.00 57.55  ? 266 PRO J CD    1 
ATOM   2032 N N     . SER A 1 261 ? 191.581 192.842 227.561 1.00 59.72  ? 267 SER J N     1 
ATOM   2033 C CA    . SER A 1 261 ? 190.537 193.675 228.141 1.00 59.72  ? 267 SER J CA    1 
ATOM   2034 C C     . SER A 1 261 ? 190.318 193.387 229.618 1.00 59.72  ? 267 SER J C     1 
ATOM   2035 O O     . SER A 1 261 ? 189.457 194.021 230.234 1.00 59.72  ? 267 SER J O     1 
ATOM   2036 C CB    . SER A 1 261 ? 189.221 193.489 227.388 1.00 59.72  ? 267 SER J CB    1 
ATOM   2037 O OG    . SER A 1 261 ? 188.706 192.184 227.580 1.00 59.72  ? 267 SER J OG    1 
ATOM   2038 N N     . PHE A 1 262 ? 191.060 192.439 230.189 1.00 56.78  ? 268 PHE J N     1 
ATOM   2039 C CA    . PHE A 1 262 ? 190.982 192.197 231.623 1.00 56.78  ? 268 PHE J CA    1 
ATOM   2040 C C     . PHE A 1 262 ? 191.600 193.344 232.408 1.00 56.78  ? 268 PHE J C     1 
ATOM   2041 O O     . PHE A 1 262 ? 191.094 193.720 233.470 1.00 56.78  ? 268 PHE J O     1 
ATOM   2042 C CB    . PHE A 1 262 ? 191.679 190.885 231.972 1.00 56.78  ? 268 PHE J CB    1 
ATOM   2043 C CG    . PHE A 1 262 ? 190.862 189.664 231.677 1.00 56.78  ? 268 PHE J CG    1 
ATOM   2044 C CD1   . PHE A 1 262 ? 189.547 189.772 231.276 1.00 56.78  ? 268 PHE J CD1   1 
ATOM   2045 C CD2   . PHE A 1 262 ? 191.412 188.405 231.808 1.00 56.78  ? 268 PHE J CD2   1 
ATOM   2046 C CE1   . PHE A 1 262 ? 188.800 188.649 231.007 1.00 56.78  ? 268 PHE J CE1   1 
ATOM   2047 C CE2   . PHE A 1 262 ? 190.669 187.282 231.544 1.00 56.78  ? 268 PHE J CE2   1 
ATOM   2048 C CZ    . PHE A 1 262 ? 189.363 187.404 231.142 1.00 56.78  ? 268 PHE J CZ    1 
ATOM   2049 N N     . ILE A 1 263 ? 192.692 193.914 231.904 1.00 58.57  ? 269 ILE J N     1 
ATOM   2050 C CA    . ILE A 1 263 ? 193.416 194.954 232.624 1.00 58.57  ? 269 ILE J CA    1 
ATOM   2051 C C     . ILE A 1 263 ? 193.153 196.308 231.984 1.00 58.57  ? 269 ILE J C     1 
ATOM   2052 O O     . ILE A 1 263 ? 193.971 197.228 232.092 1.00 58.57  ? 269 ILE J O     1 
ATOM   2053 C CB    . ILE A 1 263 ? 194.923 194.654 232.673 1.00 58.57  ? 269 ILE J CB    1 
ATOM   2054 C CG1   . ILE A 1 263 ? 195.500 194.573 231.264 1.00 58.57  ? 269 ILE J CG1   1 
ATOM   2055 C CG2   . ILE A 1 263 ? 195.177 193.362 233.411 1.00 58.57  ? 269 ILE J CG2   1 
ATOM   2056 C CD1   . ILE A 1 263 ? 196.937 194.133 231.229 1.00 58.57  ? 269 ILE J CD1   1 
ATOM   2057 N N     . GLY A 1 264 ? 192.010 196.442 231.320 1.00 63.29  ? 270 GLY J N     1 
ATOM   2058 C CA    . GLY A 1 264 ? 191.628 197.726 230.773 1.00 63.29  ? 270 GLY J CA    1 
ATOM   2059 C C     . GLY A 1 264 ? 192.419 198.173 229.570 1.00 63.29  ? 270 GLY J C     1 
ATOM   2060 O O     . GLY A 1 264 ? 192.540 199.377 229.335 1.00 63.29  ? 270 GLY J O     1 
ATOM   2061 N N     . MET A 1 265 ? 192.972 197.242 228.803 1.00 66.31  ? 271 MET J N     1 
ATOM   2062 C CA    . MET A 1 265 ? 193.653 197.564 227.560 1.00 66.31  ? 271 MET J CA    1 
ATOM   2063 C C     . MET A 1 265 ? 192.711 197.340 226.387 1.00 66.31  ? 271 MET J C     1 
ATOM   2064 O O     . MET A 1 265 ? 191.837 196.472 226.426 1.00 66.31  ? 271 MET J O     1 
ATOM   2065 C CB    . MET A 1 265 ? 194.916 196.720 227.389 1.00 66.31  ? 271 MET J CB    1 
ATOM   2066 C CG    . MET A 1 265 ? 196.035 197.095 228.341 1.00 66.31  ? 271 MET J CG    1 
ATOM   2067 S SD    . MET A 1 265 ? 197.590 196.275 227.955 1.00 66.31  ? 271 MET J SD    1 
ATOM   2068 C CE    . MET A 1 265 ? 197.795 196.743 226.242 1.00 66.31  ? 271 MET J CE    1 
ATOM   2069 N N     . GLU A 1 266 ? 192.895 198.137 225.338 1.00 72.10  ? 272 GLU J N     1 
ATOM   2070 C CA    . GLU A 1 266 ? 192.063 198.034 224.151 1.00 72.10  ? 272 GLU J CA    1 
ATOM   2071 C C     . GLU A 1 266 ? 192.669 197.150 223.072 1.00 72.10  ? 272 GLU J C     1 
ATOM   2072 O O     . GLU A 1 266 ? 191.962 196.775 222.132 1.00 72.10  ? 272 GLU J O     1 
ATOM   2073 C CB    . GLU A 1 266 ? 191.790 199.425 223.568 1.00 72.10  ? 272 GLU J CB    1 
ATOM   2074 C CG    . GLU A 1 266 ? 190.522 199.497 222.734 1.00 72.10  ? 272 GLU J CG    1 
ATOM   2075 C CD    . GLU A 1 266 ? 190.357 200.825 222.033 1.00 72.10  ? 272 GLU J CD    1 
ATOM   2076 O OE1   . GLU A 1 266 ? 191.369 201.533 221.851 1.00 72.10  ? 272 GLU J OE1   1 
ATOM   2077 O OE2   . GLU A 1 266 ? 189.214 201.161 221.662 1.00 72.10  ? 272 GLU J OE2   1 
ATOM   2078 N N     . SER A 1 267 ? 193.945 196.798 223.188 1.00 64.48  ? 273 SER J N     1 
ATOM   2079 C CA    . SER A 1 267 ? 194.619 196.047 222.143 1.00 64.48  ? 273 SER J CA    1 
ATOM   2080 C C     . SER A 1 267 ? 194.041 194.639 222.039 1.00 64.48  ? 273 SER J C     1 
ATOM   2081 O O     . SER A 1 267 ? 193.156 194.236 222.796 1.00 64.48  ? 273 SER J O     1 
ATOM   2082 C CB    . SER A 1 267 ? 196.119 196.003 222.410 1.00 64.48  ? 273 SER J CB    1 
ATOM   2083 O OG    . SER A 1 267 ? 196.745 197.197 221.978 1.00 64.48  ? 273 SER J OG    1 
ATOM   2084 N N     . ALA A 1 268 ? 194.545 193.887 221.071 1.00 57.67  ? 274 ALA J N     1 
ATOM   2085 C CA    . ALA A 1 268 ? 194.139 192.510 220.852 1.00 57.67  ? 274 ALA J CA    1 
ATOM   2086 C C     . ALA A 1 268 ? 195.066 191.566 221.604 1.00 57.67  ? 274 ALA J C     1 
ATOM   2087 O O     . ALA A 1 268 ? 196.110 191.960 222.124 1.00 57.67  ? 274 ALA J O     1 
ATOM   2088 C CB    . ALA A 1 268 ? 194.137 192.183 219.358 1.00 57.67  ? 274 ALA J CB    1 
ATOM   2089 N N     . GLY A 1 269 ? 194.670 190.299 221.659 1.00 55.76  ? 275 GLY J N     1 
ATOM   2090 C CA    . GLY A 1 269 ? 195.497 189.292 222.292 1.00 55.76  ? 275 GLY J CA    1 
ATOM   2091 C C     . GLY A 1 269 ? 196.804 189.086 221.560 1.00 55.76  ? 275 GLY J C     1 
ATOM   2092 O O     . GLY A 1 269 ? 197.047 189.722 220.534 1.00 55.76  ? 275 GLY J O     1 
ATOM   2093 N N     . ILE A 1 270 ? 197.657 188.195 222.061 1.00 54.37  ? 276 ILE J N     1 
ATOM   2094 C CA    . ILE A 1 270 ? 198.923 187.969 221.378 1.00 54.37  ? 276 ILE J CA    1 
ATOM   2095 C C     . ILE A 1 270 ? 198.720 187.113 220.136 1.00 54.37  ? 276 ILE J C     1 
ATOM   2096 O O     . ILE A 1 270 ? 199.417 187.296 219.129 1.00 54.37  ? 276 ILE J O     1 
ATOM   2097 C CB    . ILE A 1 270 ? 199.947 187.350 222.342 1.00 54.37  ? 276 ILE J CB    1 
ATOM   2098 C CG1   . ILE A 1 270 ? 199.363 186.119 223.026 1.00 54.37  ? 276 ILE J CG1   1 
ATOM   2099 C CG2   . ILE A 1 270 ? 200.379 188.370 223.371 1.00 54.37  ? 276 ILE J CG2   1 
ATOM   2100 C CD1   . ILE A 1 270 ? 200.286 185.506 224.039 1.00 54.37  ? 276 ILE J CD1   1 
ATOM   2101 N N     . HIS A 1 271 ? 197.762 186.186 220.168 1.00 56.22  ? 277 HIS J N     1 
ATOM   2102 C CA    . HIS A 1 271 ? 197.471 185.388 218.983 1.00 56.22  ? 277 HIS J CA    1 
ATOM   2103 C C     . HIS A 1 271 ? 196.978 186.263 217.838 1.00 56.22  ? 277 HIS J C     1 
ATOM   2104 O O     . HIS A 1 271 ? 197.400 186.096 216.687 1.00 56.22  ? 277 HIS J O     1 
ATOM   2105 C CB    . HIS A 1 271 ? 196.442 184.310 219.315 1.00 56.22  ? 277 HIS J CB    1 
ATOM   2106 C CG    . HIS A 1 271 ? 195.108 184.850 219.725 1.00 56.22  ? 277 HIS J CG    1 
ATOM   2107 N ND1   . HIS A 1 271 ? 194.939 185.671 220.817 1.00 56.22  ? 277 HIS J ND1   1 
ATOM   2108 C CD2   . HIS A 1 271 ? 193.878 184.686 219.186 1.00 56.22  ? 277 HIS J CD2   1 
ATOM   2109 C CE1   . HIS A 1 271 ? 193.663 185.989 220.935 1.00 56.22  ? 277 HIS J CE1   1 
ATOM   2110 N NE2   . HIS A 1 271 ? 192.997 185.403 219.958 1.00 56.22  ? 277 HIS J NE2   1 
ATOM   2111 N N     . GLU A 1 272 ? 196.098 187.218 218.135 1.00 58.89  ? 278 GLU J N     1 
ATOM   2112 C CA    . GLU A 1 272 ? 195.549 188.046 217.073 1.00 58.89  ? 278 GLU J CA    1 
ATOM   2113 C C     . GLU A 1 272 ? 196.568 189.052 216.559 1.00 58.89  ? 278 GLU J C     1 
ATOM   2114 O O     . GLU A 1 272 ? 196.585 189.345 215.362 1.00 58.89  ? 278 GLU J O     1 
ATOM   2115 C CB    . GLU A 1 272 ? 194.285 188.751 217.550 1.00 58.89  ? 278 GLU J CB    1 
ATOM   2116 C CG    . GLU A 1 272 ? 193.591 189.542 216.466 1.00 58.89  ? 278 GLU J CG    1 
ATOM   2117 C CD    . GLU A 1 272 ? 192.271 190.116 216.921 1.00 58.89  ? 278 GLU J CD    1 
ATOM   2118 O OE1   . GLU A 1 272 ? 191.889 189.880 218.087 1.00 58.89  ? 278 GLU J OE1   1 
ATOM   2119 O OE2   . GLU A 1 272 ? 191.614 190.804 216.112 1.00 58.89  ? 278 GLU J OE2   1 
ATOM   2120 N N     . THR A 1 273 ? 197.438 189.577 217.425 1.00 56.71  ? 279 THR J N     1 
ATOM   2121 C CA    . THR A 1 273 ? 198.509 190.432 216.919 1.00 56.71  ? 279 THR J CA    1 
ATOM   2122 C C     . THR A 1 273 ? 199.488 189.638 216.066 1.00 56.71  ? 279 THR J C     1 
ATOM   2123 O O     . THR A 1 273 ? 199.997 190.152 215.066 1.00 56.71  ? 279 THR J O     1 
ATOM   2124 C CB    . THR A 1 273 ? 199.248 191.128 218.059 1.00 56.71  ? 279 THR J CB    1 
ATOM   2125 O OG1   . THR A 1 273 ? 199.846 190.151 218.915 1.00 56.71  ? 279 THR J OG1   1 
ATOM   2126 C CG2   . THR A 1 273 ? 198.312 192.013 218.850 1.00 56.71  ? 279 THR J CG2   1 
ATOM   2127 N N     . THR A 1 274 ? 199.757 188.383 216.430 1.00 55.26  ? 280 THR J N     1 
ATOM   2128 C CA    . THR A 1 274 ? 200.601 187.543 215.585 1.00 55.26  ? 280 THR J CA    1 
ATOM   2129 C C     . THR A 1 274 ? 199.965 187.331 214.218 1.00 55.26  ? 280 THR J C     1 
ATOM   2130 O O     . THR A 1 274 ? 200.625 187.473 213.180 1.00 55.26  ? 280 THR J O     1 
ATOM   2131 C CB    . THR A 1 274 ? 200.867 186.204 216.268 1.00 55.26  ? 280 THR J CB    1 
ATOM   2132 O OG1   . THR A 1 274 ? 201.608 186.423 217.473 1.00 55.26  ? 280 THR J OG1   1 
ATOM   2133 C CG2   . THR A 1 274 ? 201.653 185.288 215.356 1.00 55.26  ? 280 THR J CG2   1 
ATOM   2134 N N     . TYR A 1 275 ? 198.675 186.998 214.197 1.00 57.77  ? 281 TYR J N     1 
ATOM   2135 C CA    . TYR A 1 275 ? 198.000 186.784 212.921 1.00 57.77  ? 281 TYR J CA    1 
ATOM   2136 C C     . TYR A 1 275 ? 197.959 188.062 212.092 1.00 57.77  ? 281 TYR J C     1 
ATOM   2137 O O     . TYR A 1 275 ? 198.113 188.019 210.868 1.00 57.77  ? 281 TYR J O     1 
ATOM   2138 C CB    . TYR A 1 275 ? 196.590 186.250 213.148 1.00 57.77  ? 281 TYR J CB    1 
ATOM   2139 C CG    . TYR A 1 275 ? 195.756 186.266 211.897 1.00 57.77  ? 281 TYR J CG    1 
ATOM   2140 C CD1   . TYR A 1 275 ? 195.962 185.333 210.896 1.00 57.77  ? 281 TYR J CD1   1 
ATOM   2141 C CD2   . TYR A 1 275 ? 194.771 187.222 211.709 1.00 57.77  ? 281 TYR J CD2   1 
ATOM   2142 C CE1   . TYR A 1 275 ? 195.206 185.345 209.747 1.00 57.77  ? 281 TYR J CE1   1 
ATOM   2143 C CE2   . TYR A 1 275 ? 194.011 187.244 210.562 1.00 57.77  ? 281 TYR J CE2   1 
ATOM   2144 C CZ    . TYR A 1 275 ? 194.232 186.303 209.585 1.00 57.77  ? 281 TYR J CZ    1 
ATOM   2145 O OH    . TYR A 1 275 ? 193.475 186.318 208.438 1.00 57.77  ? 281 TYR J OH    1 
ATOM   2146 N N     . ASN A 1 276 ? 197.766 189.212 212.736 1.00 56.85  ? 282 ASN J N     1 
ATOM   2147 C CA    . ASN A 1 276 ? 197.731 190.465 211.991 1.00 56.85  ? 282 ASN J CA    1 
ATOM   2148 C C     . ASN A 1 276 ? 199.104 190.818 211.441 1.00 56.85  ? 282 ASN J C     1 
ATOM   2149 O O     . ASN A 1 276 ? 199.220 191.302 210.310 1.00 56.85  ? 282 ASN J O     1 
ATOM   2150 C CB    . ASN A 1 276 ? 197.204 191.588 212.878 1.00 56.85  ? 282 ASN J CB    1 
ATOM   2151 C CG    . ASN A 1 276 ? 195.759 191.391 213.258 1.00 56.85  ? 282 ASN J CG    1 
ATOM   2152 O OD1   . ASN A 1 276 ? 194.981 190.815 212.501 1.00 56.85  ? 282 ASN J OD1   1 
ATOM   2153 N ND2   . ASN A 1 276 ? 195.388 191.867 214.436 1.00 56.85  ? 282 ASN J ND2   1 
ATOM   2154 N N     . SER A 1 277 ? 200.158 190.586 212.224 1.00 54.16  ? 283 SER J N     1 
ATOM   2155 C CA    . SER A 1 277 ? 201.506 190.825 211.730 1.00 54.16  ? 283 SER J CA    1 
ATOM   2156 C C     . SER A 1 277 ? 201.838 189.907 210.566 1.00 54.16  ? 283 SER J C     1 
ATOM   2157 O O     . SER A 1 277 ? 202.582 190.297 209.662 1.00 54.16  ? 283 SER J O     1 
ATOM   2158 C CB    . SER A 1 277 ? 202.519 190.644 212.855 1.00 54.16  ? 283 SER J CB    1 
ATOM   2159 O OG    . SER A 1 277 ? 203.811 190.423 212.331 1.00 54.16  ? 283 SER J OG    1 
ATOM   2160 N N     . ILE A 1 278 ? 201.301 188.687 210.567 1.00 54.36  ? 284 ILE J N     1 
ATOM   2161 C CA    . ILE A 1 278 ? 201.492 187.812 209.416 1.00 54.36  ? 284 ILE J CA    1 
ATOM   2162 C C     . ILE A 1 278 ? 200.721 188.340 208.214 1.00 54.36  ? 284 ILE J C     1 
ATOM   2163 O O     . ILE A 1 278 ? 201.237 188.367 207.091 1.00 54.36  ? 284 ILE J O     1 
ATOM   2164 C CB    . ILE A 1 278 ? 201.079 186.372 209.757 1.00 54.36  ? 284 ILE J CB    1 
ATOM   2165 C CG1   . ILE A 1 278 ? 202.098 185.731 210.695 1.00 54.36  ? 284 ILE J CG1   1 
ATOM   2166 C CG2   . ILE A 1 278 ? 200.951 185.559 208.497 1.00 54.36  ? 284 ILE J CG2   1 
ATOM   2167 C CD1   . ILE A 1 278 ? 201.589 184.494 211.390 1.00 54.36  ? 284 ILE J CD1   1 
ATOM   2168 N N     . MET A 1 279 ? 199.479 188.773 208.425 1.00 58.79  ? 285 MET J N     1 
ATOM   2169 C CA    . MET A 1 279 ? 198.652 189.277 207.335 1.00 58.79  ? 285 MET J CA    1 
ATOM   2170 C C     . MET A 1 279 ? 199.049 190.670 206.876 1.00 58.79  ? 285 MET J C     1 
ATOM   2171 O O     . MET A 1 279 ? 198.431 191.189 205.944 1.00 58.79  ? 285 MET J O     1 
ATOM   2172 C CB    . MET A 1 279 ? 197.182 189.273 207.744 1.00 58.79  ? 285 MET J CB    1 
ATOM   2173 C CG    . MET A 1 279 ? 196.486 187.957 207.496 1.00 58.79  ? 285 MET J CG    1 
ATOM   2174 S SD    . MET A 1 279 ? 196.163 187.691 205.748 1.00 58.79  ? 285 MET J SD    1 
ATOM   2175 C CE    . MET A 1 279 ? 195.889 185.923 205.721 1.00 58.79  ? 285 MET J CE    1 
ATOM   2176 N N     . LYS A 1 280 ? 200.042 191.291 207.500 1.00 58.12  ? 286 LYS J N     1 
ATOM   2177 C CA    . LYS A 1 280 ? 200.591 192.546 207.006 1.00 58.12  ? 286 LYS J CA    1 
ATOM   2178 C C     . LYS A 1 280 ? 201.728 192.342 206.014 1.00 58.12  ? 286 LYS J C     1 
ATOM   2179 O O     . LYS A 1 280 ? 202.139 193.304 205.360 1.00 58.12  ? 286 LYS J O     1 
ATOM   2180 C CB    . LYS A 1 280 ? 201.084 193.404 208.171 1.00 58.12  ? 286 LYS J CB    1 
ATOM   2181 C CG    . LYS A 1 280 ? 200.122 194.489 208.598 1.00 58.12  ? 286 LYS J CG    1 
ATOM   2182 C CD    . LYS A 1 280 ? 200.573 195.126 209.897 1.00 58.12  ? 286 LYS J CD    1 
ATOM   2183 C CE    . LYS A 1 280 ? 199.976 196.506 210.067 1.00 58.12  ? 286 LYS J CE    1 
ATOM   2184 N NZ    . LYS A 1 280 ? 198.520 196.508 209.776 1.00 58.12  ? 286 LYS J NZ    1 
ATOM   2185 N N     . CYS A 1 281 ? 202.238 191.124 205.884 1.00 58.44  ? 287 CYS J N     1 
ATOM   2186 C CA    . CYS A 1 281 ? 203.345 190.814 204.994 1.00 58.44  ? 287 CYS J CA    1 
ATOM   2187 C C     . CYS A 1 281 ? 202.827 190.445 203.609 1.00 58.44  ? 287 CYS J C     1 
ATOM   2188 O O     . CYS A 1 281 ? 201.625 190.291 203.387 1.00 58.44  ? 287 CYS J O     1 
ATOM   2189 C CB    . CYS A 1 281 ? 204.187 189.676 205.573 1.00 58.44  ? 287 CYS J CB    1 
ATOM   2190 S SG    . CYS A 1 281 ? 204.996 190.069 207.134 1.00 58.44  ? 287 CYS J SG    1 
ATOM   2191 N N     . ASP A 1 282 ? 203.757 190.305 202.669 1.00 63.17  ? 288 ASP J N     1 
ATOM   2192 C CA    . ASP A 1 282 ? 203.389 189.982 201.298 1.00 63.17  ? 288 ASP J CA    1 
ATOM   2193 C C     . ASP A 1 282 ? 202.843 188.562 201.210 1.00 63.17  ? 288 ASP J C     1 
ATOM   2194 O O     . ASP A 1 282 ? 203.279 187.658 201.925 1.00 63.17  ? 288 ASP J O     1 
ATOM   2195 C CB    . ASP A 1 282 ? 204.589 190.142 200.367 1.00 63.17  ? 288 ASP J CB    1 
ATOM   2196 C CG    . ASP A 1 282 ? 204.181 190.494 198.947 1.00 63.17  ? 288 ASP J CG    1 
ATOM   2197 O OD1   . ASP A 1 282 ? 203.009 190.874 198.741 1.00 63.17  ? 288 ASP J OD1   1 
ATOM   2198 O OD2   . ASP A 1 282 ? 205.030 190.392 198.036 1.00 63.17  ? 288 ASP J OD2   1 
ATOM   2199 N N     . ILE A 1 283 ? 201.883 188.372 200.304 1.00 61.17  ? 289 ILE J N     1 
ATOM   2200 C CA    . ILE A 1 283 ? 201.102 187.145 200.235 1.00 61.17  ? 289 ILE J CA    1 
ATOM   2201 C C     . ILE A 1 283 ? 201.940 185.915 199.912 1.00 61.17  ? 289 ILE J C     1 
ATOM   2202 O O     . ILE A 1 283 ? 201.457 184.791 200.062 1.00 61.17  ? 289 ILE J O     1 
ATOM   2203 C CB    . ILE A 1 283 ? 199.966 187.318 199.201 1.00 61.17  ? 289 ILE J CB    1 
ATOM   2204 C CG1   . ILE A 1 283 ? 198.911 186.224 199.354 1.00 61.17  ? 289 ILE J CG1   1 
ATOM   2205 C CG2   . ILE A 1 283 ? 200.520 187.305 197.796 1.00 61.17  ? 289 ILE J CG2   1 
ATOM   2206 C CD1   . ILE A 1 283 ? 197.638 186.505 198.601 1.00 61.17  ? 289 ILE J CD1   1 
ATOM   2207 N N     . ASP A 1 284 ? 203.190 186.090 199.496 1.00 62.03  ? 290 ASP J N     1 
ATOM   2208 C CA    . ASP A 1 284 ? 204.008 184.958 199.087 1.00 62.03  ? 290 ASP J CA    1 
ATOM   2209 C C     . ASP A 1 284 ? 204.868 184.390 200.206 1.00 62.03  ? 290 ASP J C     1 
ATOM   2210 O O     . ASP A 1 284 ? 205.455 183.319 200.027 1.00 62.03  ? 290 ASP J O     1 
ATOM   2211 C CB    . ASP A 1 284 ? 204.907 185.353 197.917 1.00 62.03  ? 290 ASP J CB    1 
ATOM   2212 C CG    . ASP A 1 284 ? 204.126 185.921 196.758 1.00 62.03  ? 290 ASP J CG    1 
ATOM   2213 O OD1   . ASP A 1 284 ? 203.574 187.030 196.902 1.00 62.03  ? 290 ASP J OD1   1 
ATOM   2214 O OD2   . ASP A 1 284 ? 204.053 185.253 195.707 1.00 62.03  ? 290 ASP J OD2   1 
ATOM   2215 N N     . ILE A 1 285 ? 204.965 185.068 201.346 1.00 58.59  ? 291 ILE J N     1 
ATOM   2216 C CA    . ILE A 1 285 ? 205.806 184.607 202.445 1.00 58.59  ? 291 ILE J CA    1 
ATOM   2217 C C     . ILE A 1 285 ? 205.012 184.172 203.663 1.00 58.59  ? 291 ILE J C     1 
ATOM   2218 O O     . ILE A 1 285 ? 205.596 183.565 204.577 1.00 58.59  ? 291 ILE J O     1 
ATOM   2219 C CB    . ILE A 1 285 ? 206.835 185.679 202.854 1.00 58.59  ? 291 ILE J CB    1 
ATOM   2220 C CG1   . ILE A 1 285 ? 206.124 186.868 203.495 1.00 58.59  ? 291 ILE J CG1   1 
ATOM   2221 C CG2   . ILE A 1 285 ? 207.644 186.118 201.653 1.00 58.59  ? 291 ILE J CG2   1 
ATOM   2222 C CD1   . ILE A 1 285 ? 207.053 187.960 203.942 1.00 58.59  ? 291 ILE J CD1   1 
ATOM   2223 N N     . ARG A 1 286 ? 203.712 184.455 203.719 1.00 56.95  ? 292 ARG J N     1 
ATOM   2224 C CA    . ARG A 1 286 ? 202.965 184.093 204.913 1.00 56.95  ? 292 ARG J CA    1 
ATOM   2225 C C     . ARG A 1 286 ? 202.762 182.592 205.032 1.00 56.95  ? 292 ARG J C     1 
ATOM   2226 O O     . ARG A 1 286 ? 202.585 182.097 206.147 1.00 56.95  ? 292 ARG J O     1 
ATOM   2227 C CB    . ARG A 1 286 ? 201.626 184.820 204.947 1.00 56.95  ? 292 ARG J CB    1 
ATOM   2228 C CG    . ARG A 1 286 ? 200.902 184.875 203.639 1.00 56.95  ? 292 ARG J CG    1 
ATOM   2229 C CD    . ARG A 1 286 ? 199.668 185.744 203.770 1.00 56.95  ? 292 ARG J CD    1 
ATOM   2230 N NE    . ARG A 1 286 ? 199.978 187.166 203.672 1.00 56.95  ? 292 ARG J NE    1 
ATOM   2231 C CZ    . ARG A 1 286 ? 199.090 188.097 203.345 1.00 56.95  ? 292 ARG J CZ    1 
ATOM   2232 N NH1   . ARG A 1 286 ? 197.838 187.755 203.086 1.00 56.95  ? 292 ARG J NH1   1 
ATOM   2233 N NH2   . ARG A 1 286 ? 199.449 189.368 203.277 1.00 56.95  ? 292 ARG J NH2   1 
ATOM   2234 N N     . LYS A 1 287 ? 202.835 181.849 203.928 1.00 59.01  ? 293 LYS J N     1 
ATOM   2235 C CA    . LYS A 1 287 ? 202.750 180.395 204.028 1.00 59.01  ? 293 LYS J CA    1 
ATOM   2236 C C     . LYS A 1 287 ? 203.889 179.841 204.872 1.00 59.01  ? 293 LYS J C     1 
ATOM   2237 O O     . LYS A 1 287 ? 203.709 178.863 205.606 1.00 59.01  ? 293 LYS J O     1 
ATOM   2238 C CB    . LYS A 1 287 ? 202.758 179.767 202.635 1.00 59.01  ? 293 LYS J CB    1 
ATOM   2239 C CG    . LYS A 1 287 ? 202.551 178.258 202.622 1.00 59.01  ? 293 LYS J CG    1 
ATOM   2240 C CD    . LYS A 1 287 ? 203.861 177.489 202.576 1.00 59.01  ? 293 LYS J CD    1 
ATOM   2241 C CE    . LYS A 1 287 ? 204.550 177.645 201.233 1.00 59.01  ? 293 LYS J CE    1 
ATOM   2242 N NZ    . LYS A 1 287 ? 205.818 176.871 201.166 1.00 59.01  ? 293 LYS J NZ    1 
ATOM   2243 N N     . ASP A 1 288 ? 205.069 180.452 204.781 1.00 58.88  ? 294 ASP J N     1 
ATOM   2244 C CA    . ASP A 1 288 ? 206.214 180.028 205.573 1.00 58.88  ? 294 ASP J CA    1 
ATOM   2245 C C     . ASP A 1 288 ? 206.295 180.724 206.922 1.00 58.88  ? 294 ASP J C     1 
ATOM   2246 O O     . ASP A 1 288 ? 206.850 180.151 207.864 1.00 58.88  ? 294 ASP J O     1 
ATOM   2247 C CB    . ASP A 1 288 ? 207.508 180.269 204.798 1.00 58.88  ? 294 ASP J CB    1 
ATOM   2248 C CG    . ASP A 1 288 ? 207.805 179.161 203.814 1.00 58.88  ? 294 ASP J CG    1 
ATOM   2249 O OD1   . ASP A 1 288 ? 207.531 177.989 204.146 1.00 58.88  ? 294 ASP J OD1   1 
ATOM   2250 O OD2   . ASP A 1 288 ? 208.309 179.457 202.710 1.00 58.88  ? 294 ASP J OD2   1 
ATOM   2251 N N     . LEU A 1 289 ? 205.767 181.942 207.038 1.00 54.43  ? 295 LEU J N     1 
ATOM   2252 C CA    . LEU A 1 289 ? 205.629 182.546 208.361 1.00 54.43  ? 295 LEU J CA    1 
ATOM   2253 C C     . LEU A 1 289 ? 204.669 181.764 209.249 1.00 54.43  ? 295 LEU J C     1 
ATOM   2254 O O     . LEU A 1 289 ? 204.845 181.742 210.470 1.00 54.43  ? 295 LEU J O     1 
ATOM   2255 C CB    . LEU A 1 289 ? 205.176 183.999 208.248 1.00 54.43  ? 295 LEU J CB    1 
ATOM   2256 C CG    . LEU A 1 289 ? 206.260 185.073 208.188 1.00 54.43  ? 295 LEU J CG    1 
ATOM   2257 C CD1   . LEU A 1 289 ? 207.071 184.997 206.927 1.00 54.43  ? 295 LEU J CD1   1 
ATOM   2258 C CD2   . LEU A 1 289 ? 205.608 186.423 208.286 1.00 54.43  ? 295 LEU J CD2   1 
ATOM   2259 N N     . TYR A 1 290 ? 203.654 181.122 208.667 1.00 57.62  ? 296 TYR J N     1 
ATOM   2260 C CA    . TYR A 1 290 ? 202.695 180.386 209.482 1.00 57.62  ? 296 TYR J CA    1 
ATOM   2261 C C     . TYR A 1 290 ? 203.332 179.191 210.177 1.00 57.62  ? 296 TYR J C     1 
ATOM   2262 O O     . TYR A 1 290 ? 203.006 178.905 211.333 1.00 57.62  ? 296 TYR J O     1 
ATOM   2263 C CB    . TYR A 1 290 ? 201.519 179.920 208.627 1.00 57.62  ? 296 TYR J CB    1 
ATOM   2264 C CG    . TYR A 1 290 ? 200.466 180.974 208.403 1.00 57.62  ? 296 TYR J CG    1 
ATOM   2265 C CD1   . TYR A 1 290 ? 200.033 181.779 209.441 1.00 57.62  ? 296 TYR J CD1   1 
ATOM   2266 C CD2   . TYR A 1 290 ? 199.901 181.160 207.153 1.00 57.62  ? 296 TYR J CD2   1 
ATOM   2267 C CE1   . TYR A 1 290 ? 199.069 182.741 209.240 1.00 57.62  ? 296 TYR J CE1   1 
ATOM   2268 C CE2   . TYR A 1 290 ? 198.941 182.121 206.941 1.00 57.62  ? 296 TYR J CE2   1 
ATOM   2269 C CZ    . TYR A 1 290 ? 198.528 182.909 207.987 1.00 57.62  ? 296 TYR J CZ    1 
ATOM   2270 O OH    . TYR A 1 290 ? 197.566 183.868 207.775 1.00 57.62  ? 296 TYR J OH    1 
ATOM   2271 N N     . ALA A 1 291 ? 204.234 178.485 209.504 1.00 56.06  ? 297 ALA J N     1 
ATOM   2272 C CA    . ALA A 1 291 ? 204.791 177.250 210.034 1.00 56.06  ? 297 ALA J CA    1 
ATOM   2273 C C     . ALA A 1 291 ? 206.063 177.467 210.841 1.00 56.06  ? 297 ALA J C     1 
ATOM   2274 O O     . ALA A 1 291 ? 206.763 176.498 211.143 1.00 56.06  ? 297 ALA J O     1 
ATOM   2275 C CB    . ALA A 1 291 ? 205.059 176.266 208.896 1.00 56.06  ? 297 ALA J CB    1 
ATOM   2276 N N     . ASN A 1 292 ? 206.386 178.708 211.191 1.00 54.58  ? 298 ASN J N     1 
ATOM   2277 C CA    . ASN A 1 292 ? 207.600 179.001 211.941 1.00 54.58  ? 298 ASN J CA    1 
ATOM   2278 C C     . ASN A 1 292 ? 207.334 180.044 213.022 1.00 54.58  ? 298 ASN J C     1 
ATOM   2279 O O     . ASN A 1 292 ? 208.098 180.991 213.202 1.00 54.58  ? 298 ASN J O     1 
ATOM   2280 C CB    . ASN A 1 292 ? 208.712 179.452 211.002 1.00 54.58  ? 298 ASN J CB    1 
ATOM   2281 C CG    . ASN A 1 292 ? 209.276 178.314 210.185 1.00 54.58  ? 298 ASN J CG    1 
ATOM   2282 O OD1   . ASN A 1 292 ? 210.297 177.731 210.539 1.00 54.58  ? 298 ASN J OD1   1 
ATOM   2283 N ND2   . ASN A 1 292 ? 208.613 177.988 209.085 1.00 54.58  ? 298 ASN J ND2   1 
ATOM   2284 N N     . ASN A 1 293 ? 206.236 179.890 213.751 1.00 53.18  ? 299 ASN J N     1 
ATOM   2285 C CA    . ASN A 1 293 ? 205.958 180.761 214.892 1.00 53.18  ? 299 ASN J CA    1 
ATOM   2286 C C     . ASN A 1 293 ? 206.910 180.399 216.022 1.00 53.18  ? 299 ASN J C     1 
ATOM   2287 O O     . ASN A 1 293 ? 206.730 179.388 216.700 1.00 53.18  ? 299 ASN J O     1 
ATOM   2288 C CB    . ASN A 1 293 ? 204.509 180.623 215.337 1.00 53.18  ? 299 ASN J CB    1 
ATOM   2289 C CG    . ASN A 1 293 ? 203.533 181.155 214.316 1.00 53.18  ? 299 ASN J CG    1 
ATOM   2290 O OD1   . ASN A 1 293 ? 203.434 182.361 214.109 1.00 53.18  ? 299 ASN J OD1   1 
ATOM   2291 N ND2   . ASN A 1 293 ? 202.798 180.257 213.676 1.00 53.18  ? 299 ASN J ND2   1 
ATOM   2292 N N     . VAL A 1 294 ? 207.925 181.226 216.234 1.00 50.09  ? 300 VAL J N     1 
ATOM   2293 C CA    . VAL A 1 294 ? 208.958 180.970 217.229 1.00 50.09  ? 300 VAL J CA    1 
ATOM   2294 C C     . VAL A 1 294 ? 208.626 181.761 218.486 1.00 50.09  ? 300 VAL J C     1 
ATOM   2295 O O     . VAL A 1 294 ? 208.525 182.991 218.446 1.00 50.09  ? 300 VAL J O     1 
ATOM   2296 C CB    . VAL A 1 294 ? 210.350 181.339 216.698 1.00 50.09  ? 300 VAL J CB    1 
ATOM   2297 C CG1   . VAL A 1 294 ? 211.386 181.183 217.788 1.00 50.09  ? 300 VAL J CG1   1 
ATOM   2298 C CG2   . VAL A 1 294 ? 210.702 180.475 215.507 1.00 50.09  ? 300 VAL J CG2   1 
ATOM   2299 N N     . LEU A 1 295 ? 208.456 181.058 219.599 1.00 48.89  ? 301 LEU J N     1 
ATOM   2300 C CA    . LEU A 1 295 ? 208.191 181.688 220.884 1.00 48.89  ? 301 LEU J CA    1 
ATOM   2301 C C     . LEU A 1 295 ? 209.495 181.892 221.643 1.00 48.89  ? 301 LEU J C     1 
ATOM   2302 O O     . LEU A 1 295 ? 210.388 181.043 221.606 1.00 48.89  ? 301 LEU J O     1 
ATOM   2303 C CB    . LEU A 1 295 ? 207.236 180.833 221.714 1.00 48.89  ? 301 LEU J CB    1 
ATOM   2304 C CG    . LEU A 1 295 ? 205.736 181.106 221.635 1.00 48.89  ? 301 LEU J CG    1 
ATOM   2305 C CD1   . LEU A 1 295 ? 205.251 181.088 220.207 1.00 48.89  ? 301 LEU J CD1   1 
ATOM   2306 C CD2   . LEU A 1 295 ? 204.991 180.078 222.453 1.00 48.89  ? 301 LEU J CD2   1 
ATOM   2307 N N     . SER A 1 296 ? 209.601 183.023 222.335 1.00 50.69  ? 302 SER J N     1 
ATOM   2308 C CA    . SER A 1 296 ? 210.791 183.310 223.119 1.00 50.69  ? 302 SER J CA    1 
ATOM   2309 C C     . SER A 1 296 ? 210.443 184.293 224.223 1.00 50.69  ? 302 SER J C     1 
ATOM   2310 O O     . SER A 1 296 ? 209.438 185.002 224.157 1.00 50.69  ? 302 SER J O     1 
ATOM   2311 C CB    . SER A 1 296 ? 211.919 183.872 222.255 1.00 50.69  ? 302 SER J CB    1 
ATOM   2312 O OG    . SER A 1 296 ? 211.590 185.158 221.771 1.00 50.69  ? 302 SER J OG    1 
ATOM   2313 N N     . GLY A 1 297 ? 211.296 184.331 225.238 1.00 49.88  ? 303 GLY J N     1 
ATOM   2314 C CA    . GLY A 1 297 ? 211.083 185.177 226.390 1.00 49.88  ? 303 GLY J CA    1 
ATOM   2315 C C     . GLY A 1 297 ? 210.467 184.428 227.554 1.00 49.88  ? 303 GLY J C     1 
ATOM   2316 O O     . GLY A 1 297 ? 209.992 183.298 227.438 1.00 49.88  ? 303 GLY J O     1 
ATOM   2317 N N     . GLY A 1 298 ? 210.471 185.090 228.705 1.00 50.49  ? 304 GLY J N     1 
ATOM   2318 C CA    . GLY A 1 298 ? 210.002 184.471 229.926 1.00 50.49  ? 304 GLY J CA    1 
ATOM   2319 C C     . GLY A 1 298 ? 208.501 184.298 229.993 1.00 50.49  ? 304 GLY J C     1 
ATOM   2320 O O     . GLY A 1 298 ? 208.012 183.256 230.432 1.00 50.49  ? 304 GLY J O     1 
ATOM   2321 N N     . THR A 1 299 ? 207.757 185.313 229.558 1.00 51.67  ? 305 THR J N     1 
ATOM   2322 C CA    . THR A 1 299 ? 206.303 185.282 229.645 1.00 51.67  ? 305 THR J CA    1 
ATOM   2323 C C     . THR A 1 299 ? 205.681 184.212 228.754 1.00 51.67  ? 305 THR J C     1 
ATOM   2324 O O     . THR A 1 299 ? 204.510 183.875 228.939 1.00 51.67  ? 305 THR J O     1 
ATOM   2325 C CB    . THR A 1 299 ? 205.753 186.668 229.296 1.00 51.67  ? 305 THR J CB    1 
ATOM   2326 O OG1   . THR A 1 299 ? 206.402 187.647 230.114 1.00 51.67  ? 305 THR J OG1   1 
ATOM   2327 C CG2   . THR A 1 299 ? 204.265 186.756 229.563 1.00 51.67  ? 305 THR J CG2   1 
ATOM   2328 N N     . THR A 1 300 ? 206.437 183.641 227.817 1.00 50.12  ? 306 THR J N     1 
ATOM   2329 C CA    . THR A 1 300 ? 205.941 182.567 226.967 1.00 50.12  ? 306 THR J CA    1 
ATOM   2330 C C     . THR A 1 300 ? 206.202 181.191 227.559 1.00 50.12  ? 306 THR J C     1 
ATOM   2331 O O     . THR A 1 300 ? 206.327 180.212 226.814 1.00 50.12  ? 306 THR J O     1 
ATOM   2332 C CB    . THR A 1 300 ? 206.561 182.664 225.574 1.00 50.12  ? 306 THR J CB    1 
ATOM   2333 O OG1   . THR A 1 300 ? 207.975 182.481 225.670 1.00 50.12  ? 306 THR J OG1   1 
ATOM   2334 C CG2   . THR A 1 300 ? 206.284 184.016 224.961 1.00 50.12  ? 306 THR J CG2   1 
ATOM   2335 N N     . MET A 1 301 ? 206.290 181.091 228.883 1.00 54.39  ? 307 MET J N     1 
ATOM   2336 C CA    . MET A 1 301 ? 206.667 179.856 229.550 1.00 54.39  ? 307 MET J CA    1 
ATOM   2337 C C     . MET A 1 301 ? 205.520 179.194 230.298 1.00 54.39  ? 307 MET J C     1 
ATOM   2338 O O     . MET A 1 301 ? 205.740 178.167 230.944 1.00 54.39  ? 307 MET J O     1 
ATOM   2339 C CB    . MET A 1 301 ? 207.820 180.121 230.522 1.00 54.39  ? 307 MET J CB    1 
ATOM   2340 C CG    . MET A 1 301 ? 209.195 179.974 229.911 1.00 54.39  ? 307 MET J CG    1 
ATOM   2341 S SD    . MET A 1 301 ? 209.586 178.260 229.538 1.00 54.39  ? 307 MET J SD    1 
ATOM   2342 C CE    . MET A 1 301 ? 211.300 178.413 229.074 1.00 54.39  ? 307 MET J CE    1 
ATOM   2343 N N     . TYR A 1 302 ? 204.312 179.743 230.234 1.00 53.79  ? 308 TYR J N     1 
ATOM   2344 C CA    . TYR A 1 302 ? 203.198 179.154 230.962 1.00 53.79  ? 308 TYR J CA    1 
ATOM   2345 C C     . TYR A 1 302 ? 202.853 177.784 230.388 1.00 53.79  ? 308 TYR J C     1 
ATOM   2346 O O     . TYR A 1 302 ? 202.824 177.612 229.168 1.00 53.79  ? 308 TYR J O     1 
ATOM   2347 C CB    . TYR A 1 302 ? 201.972 180.057 230.903 1.00 53.79  ? 308 TYR J CB    1 
ATOM   2348 C CG    . TYR A 1 302 ? 202.165 181.381 231.587 1.00 53.79  ? 308 TYR J CG    1 
ATOM   2349 C CD1   . TYR A 1 302 ? 201.893 181.532 232.935 1.00 53.79  ? 308 TYR J CD1   1 
ATOM   2350 C CD2   . TYR A 1 302 ? 202.615 182.481 230.884 1.00 53.79  ? 308 TYR J CD2   1 
ATOM   2351 C CE1   . TYR A 1 302 ? 202.070 182.740 233.562 1.00 53.79  ? 308 TYR J CE1   1 
ATOM   2352 C CE2   . TYR A 1 302 ? 202.794 183.691 231.502 1.00 53.79  ? 308 TYR J CE2   1 
ATOM   2353 C CZ    . TYR A 1 302 ? 202.520 183.817 232.840 1.00 53.79  ? 308 TYR J CZ    1 
ATOM   2354 O OH    . TYR A 1 302 ? 202.702 185.031 233.455 1.00 53.79  ? 308 TYR J OH    1 
ATOM   2355 N N     . PRO A 1 303 ? 202.596 176.794 231.238 1.00 53.65  ? 309 PRO J N     1 
ATOM   2356 C CA    . PRO A 1 303 ? 202.241 175.460 230.737 1.00 53.65  ? 309 PRO J CA    1 
ATOM   2357 C C     . PRO A 1 303 ? 200.963 175.505 229.917 1.00 53.65  ? 309 PRO J C     1 
ATOM   2358 O O     . PRO A 1 303 ? 199.914 175.941 230.391 1.00 53.65  ? 309 PRO J O     1 
ATOM   2359 C CB    . PRO A 1 303 ? 202.065 174.642 232.019 1.00 53.65  ? 309 PRO J CB    1 
ATOM   2360 C CG    . PRO A 1 303 ? 202.877 175.360 233.032 1.00 53.65  ? 309 PRO J CG    1 
ATOM   2361 C CD    . PRO A 1 303 ? 202.756 176.809 232.698 1.00 53.65  ? 309 PRO J CD    1 
ATOM   2362 N N     . GLY A 1 304 ? 201.059 175.051 228.673 1.00 54.73  ? 310 GLY J N     1 
ATOM   2363 C CA    . GLY A 1 304 ? 199.919 175.046 227.785 1.00 54.73  ? 310 GLY J CA    1 
ATOM   2364 C C     . GLY A 1 304 ? 199.730 176.301 226.969 1.00 54.73  ? 310 GLY J C     1 
ATOM   2365 O O     . GLY A 1 304 ? 198.623 176.536 226.477 1.00 54.73  ? 310 GLY J O     1 
ATOM   2366 N N     . ILE A 1 305 ? 200.768 177.120 226.809 1.00 54.11  ? 311 ILE J N     1 
ATOM   2367 C CA    . ILE A 1 305 ? 200.629 178.307 225.976 1.00 54.11  ? 311 ILE J CA    1 
ATOM   2368 C C     . ILE A 1 305 ? 200.812 177.960 224.504 1.00 54.11  ? 311 ILE J C     1 
ATOM   2369 O O     . ILE A 1 305 ? 200.199 178.590 223.636 1.00 54.11  ? 311 ILE J O     1 
ATOM   2370 C CB    . ILE A 1 305 ? 201.611 179.401 226.426 1.00 54.11  ? 311 ILE J CB    1 
ATOM   2371 C CG1   . ILE A 1 305 ? 201.295 180.719 225.727 1.00 54.11  ? 311 ILE J CG1   1 
ATOM   2372 C CG2   . ILE A 1 305 ? 203.043 178.993 226.148 1.00 54.11  ? 311 ILE J CG2   1 
ATOM   2373 C CD1   . ILE A 1 305 ? 202.004 181.898 226.320 1.00 54.11  ? 311 ILE J CD1   1 
ATOM   2374 N N     . ALA A 1 306 ? 201.621 176.946 224.196 1.00 56.12  ? 312 ALA J N     1 
ATOM   2375 C CA    . ALA A 1 306 ? 201.819 176.562 222.804 1.00 56.12  ? 312 ALA J CA    1 
ATOM   2376 C C     . ALA A 1 306 ? 200.549 175.969 222.211 1.00 56.12  ? 312 ALA J C     1 
ATOM   2377 O O     . ALA A 1 306 ? 200.159 176.319 221.091 1.00 56.12  ? 312 ALA J O     1 
ATOM   2378 C CB    . ALA A 1 306 ? 202.978 175.575 222.691 1.00 56.12  ? 312 ALA J CB    1 
ATOM   2379 N N     . ASP A 1 307 ? 199.886 175.079 222.949 1.00 58.24  ? 313 ASP J N     1 
ATOM   2380 C CA    . ASP A 1 307 ? 198.657 174.472 222.450 1.00 58.24  ? 313 ASP J CA    1 
ATOM   2381 C C     . ASP A 1 307 ? 197.572 175.518 222.240 1.00 58.24  ? 313 ASP J C     1 
ATOM   2382 O O     . ASP A 1 307 ? 196.864 175.495 221.227 1.00 58.24  ? 313 ASP J O     1 
ATOM   2383 C CB    . ASP A 1 307 ? 198.181 173.400 223.423 1.00 58.24  ? 313 ASP J CB    1 
ATOM   2384 C CG    . ASP A 1 307 ? 199.148 172.243 223.525 1.00 58.24  ? 313 ASP J CG    1 
ATOM   2385 O OD1   . ASP A 1 307 ? 199.854 171.974 222.532 1.00 58.24  ? 313 ASP J OD1   1 
ATOM   2386 O OD2   . ASP A 1 307 ? 199.208 171.608 224.599 1.00 58.24  ? 313 ASP J OD2   1 
ATOM   2387 N N     . ARG A 1 308 ? 197.438 176.454 223.179 1.00 56.11  ? 314 ARG J N     1 
ATOM   2388 C CA    . ARG A 1 308 ? 196.411 177.481 223.054 1.00 56.11  ? 314 ARG J CA    1 
ATOM   2389 C C     . ARG A 1 308 ? 196.718 178.431 221.905 1.00 56.11  ? 314 ARG J C     1 
ATOM   2390 O O     . ARG A 1 308 ? 195.817 178.805 221.143 1.00 56.11  ? 314 ARG J O     1 
ATOM   2391 C CB    . ARG A 1 308 ? 196.283 178.248 224.366 1.00 56.11  ? 314 ARG J CB    1 
ATOM   2392 C CG    . ARG A 1 308 ? 195.544 179.555 224.241 1.00 56.11  ? 314 ARG J CG    1 
ATOM   2393 C CD    . ARG A 1 308 ? 194.056 179.333 224.100 1.00 56.11  ? 314 ARG J CD    1 
ATOM   2394 N NE    . ARG A 1 308 ? 193.314 180.574 224.281 1.00 56.11  ? 314 ARG J NE    1 
ATOM   2395 C CZ    . ARG A 1 308 ? 192.848 181.001 225.448 1.00 56.11  ? 314 ARG J CZ    1 
ATOM   2396 N NH1   . ARG A 1 308 ? 193.044 180.283 226.543 1.00 56.11  ? 314 ARG J NH1   1 
ATOM   2397 N NH2   . ARG A 1 308 ? 192.184 182.144 225.521 1.00 56.11  ? 314 ARG J NH2   1 
ATOM   2398 N N     . MET A 1 309 ? 197.982 178.827 221.759 1.00 56.51  ? 315 MET J N     1 
ATOM   2399 C CA    . MET A 1 309 ? 198.362 179.689 220.648 1.00 56.51  ? 315 MET J CA    1 
ATOM   2400 C C     . MET A 1 309 ? 198.080 179.010 219.316 1.00 56.51  ? 315 MET J C     1 
ATOM   2401 O O     . MET A 1 309 ? 197.540 179.628 218.390 1.00 56.51  ? 315 MET J O     1 
ATOM   2402 C CB    . MET A 1 309 ? 199.839 180.060 220.761 1.00 56.51  ? 315 MET J CB    1 
ATOM   2403 C CG    . MET A 1 309 ? 200.310 181.048 219.721 1.00 56.51  ? 315 MET J CG    1 
ATOM   2404 S SD    . MET A 1 309 ? 200.030 182.737 220.251 1.00 56.51  ? 315 MET J SD    1 
ATOM   2405 C CE    . MET A 1 309 ? 200.478 182.585 221.972 1.00 56.51  ? 315 MET J CE    1 
ATOM   2406 N N     . GLN A 1 310 ? 198.438 177.731 219.203 1.00 58.39  ? 316 GLN J N     1 
ATOM   2407 C CA    . GLN A 1 310 ? 198.211 177.013 217.957 1.00 58.39  ? 316 GLN J CA    1 
ATOM   2408 C C     . GLN A 1 310 ? 196.725 176.886 217.659 1.00 58.39  ? 316 GLN J C     1 
ATOM   2409 O O     . GLN A 1 310 ? 196.300 177.088 216.518 1.00 58.39  ? 316 GLN J O     1 
ATOM   2410 C CB    . GLN A 1 310 ? 198.864 175.638 218.018 1.00 58.39  ? 316 GLN J CB    1 
ATOM   2411 C CG    . GLN A 1 310 ? 198.467 174.728 216.884 1.00 58.39  ? 316 GLN J CG    1 
ATOM   2412 C CD    . GLN A 1 310 ? 199.317 173.484 216.825 1.00 58.39  ? 316 GLN J CD    1 
ATOM   2413 O OE1   . GLN A 1 310 ? 200.525 173.534 217.051 1.00 58.39  ? 316 GLN J OE1   1 
ATOM   2414 N NE2   . GLN A 1 310 ? 198.690 172.355 216.525 1.00 58.39  ? 316 GLN J NE2   1 
ATOM   2415 N N     . LYS A 1 311 ? 195.918 176.564 218.672 1.00 59.10  ? 317 LYS J N     1 
ATOM   2416 C CA    . LYS A 1 311 ? 194.478 176.451 218.462 1.00 59.10  ? 317 LYS J CA    1 
ATOM   2417 C C     . LYS A 1 311 ? 193.877 177.776 218.007 1.00 59.10  ? 317 LYS J C     1 
ATOM   2418 O O     . LYS A 1 311 ? 193.073 177.811 217.067 1.00 59.10  ? 317 LYS J O     1 
ATOM   2419 C CB    . LYS A 1 311 ? 193.810 175.960 219.744 1.00 59.10  ? 317 LYS J CB    1 
ATOM   2420 C CG    . LYS A 1 311 ? 192.300 175.983 219.726 1.00 59.10  ? 317 LYS J CG    1 
ATOM   2421 C CD    . LYS A 1 311 ? 191.745 175.149 220.867 1.00 59.10  ? 317 LYS J CD    1 
ATOM   2422 C CE    . LYS A 1 311 ? 190.307 175.515 221.182 1.00 59.10  ? 317 LYS J CE    1 
ATOM   2423 N NZ    . LYS A 1 311 ? 190.204 176.860 221.810 1.00 59.10  ? 317 LYS J NZ    1 
ATOM   2424 N N     . GLU A 1 312 ? 194.275 178.880 218.642 1.00 59.65  ? 318 GLU J N     1 
ATOM   2425 C CA    . GLU A 1 312 ? 193.749 180.186 218.258 1.00 59.65  ? 318 GLU J CA    1 
ATOM   2426 C C     . GLU A 1 312 ? 194.135 180.543 216.828 1.00 59.65  ? 318 GLU J C     1 
ATOM   2427 O O     . GLU A 1 312 ? 193.276 180.892 216.008 1.00 59.65  ? 318 GLU J O     1 
ATOM   2428 C CB    . GLU A 1 312 ? 194.247 181.255 219.227 1.00 59.65  ? 318 GLU J CB    1 
ATOM   2429 C CG    . GLU A 1 312 ? 193.704 181.114 220.629 1.00 59.65  ? 318 GLU J CG    1 
ATOM   2430 C CD    . GLU A 1 312 ? 192.254 181.513 220.724 1.00 59.65  ? 318 GLU J CD    1 
ATOM   2431 O OE1   . GLU A 1 312 ? 191.850 182.446 220.000 1.00 59.65  ? 318 GLU J OE1   1 
ATOM   2432 O OE2   . GLU A 1 312 ? 191.515 180.894 221.517 1.00 59.65  ? 318 GLU J OE2   1 
ATOM   2433 N N     . ILE A 1 313 ? 195.428 180.470 216.509 1.00 58.13  ? 319 ILE J N     1 
ATOM   2434 C CA    . ILE A 1 313 ? 195.868 180.870 215.177 1.00 58.13  ? 319 ILE J CA    1 
ATOM   2435 C C     . ILE A 1 313 ? 195.299 179.940 214.111 1.00 58.13  ? 319 ILE J C     1 
ATOM   2436 O O     . ILE A 1 313 ? 195.006 180.377 212.993 1.00 58.13  ? 319 ILE J O     1 
ATOM   2437 C CB    . ILE A 1 313 ? 197.405 180.937 215.128 1.00 58.13  ? 319 ILE J CB    1 
ATOM   2438 C CG1   . ILE A 1 313 ? 197.895 182.123 215.951 1.00 58.13  ? 319 ILE J CG1   1 
ATOM   2439 C CG2   . ILE A 1 313 ? 197.900 181.081 213.706 1.00 58.13  ? 319 ILE J CG2   1 
ATOM   2440 C CD1   . ILE A 1 313 ? 199.378 182.122 216.187 1.00 58.13  ? 319 ILE J CD1   1 
ATOM   2441 N N     . THR A 1 314 ? 195.101 178.659 214.432 1.00 58.93  ? 320 THR J N     1 
ATOM   2442 C CA    . THR A 1 314 ? 194.479 177.749 213.479 1.00 58.93  ? 320 THR J CA    1 
ATOM   2443 C C     . THR A 1 314 ? 193.018 178.107 213.255 1.00 58.93  ? 320 THR J C     1 
ATOM   2444 O O     . THR A 1 314 ? 192.521 178.033 212.127 1.00 58.93  ? 320 THR J O     1 
ATOM   2445 C CB    . THR A 1 314 ? 194.613 176.307 213.967 1.00 58.93  ? 320 THR J CB    1 
ATOM   2446 O OG1   . THR A 1 314 ? 195.999 175.960 214.050 1.00 58.93  ? 320 THR J OG1   1 
ATOM   2447 C CG2   . THR A 1 314 ? 193.925 175.353 213.014 1.00 58.93  ? 320 THR J CG2   1 
ATOM   2448 N N     . ALA A 1 315 ? 192.314 178.509 214.314 1.00 60.03  ? 321 ALA J N     1 
ATOM   2449 C CA    . ALA A 1 315 ? 190.954 178.998 214.133 1.00 60.03  ? 321 ALA J CA    1 
ATOM   2450 C C     . ALA A 1 315 ? 190.913 180.306 213.357 1.00 60.03  ? 321 ALA J C     1 
ATOM   2451 O O     . ALA A 1 315 ? 189.879 180.628 212.765 1.00 60.03  ? 321 ALA J O     1 
ATOM   2452 C CB    . ALA A 1 315 ? 190.270 179.177 215.487 1.00 60.03  ? 321 ALA J CB    1 
ATOM   2453 N N     . LEU A 1 316 ? 192.007 181.066 213.349 1.00 59.44  ? 322 LEU J N     1 
ATOM   2454 C CA    . LEU A 1 316 ? 192.055 182.320 212.605 1.00 59.44  ? 322 LEU J CA    1 
ATOM   2455 C C     . LEU A 1 316 ? 192.522 182.129 211.164 1.00 59.44  ? 322 LEU J C     1 
ATOM   2456 O O     . LEU A 1 316 ? 191.899 182.649 210.234 1.00 59.44  ? 322 LEU J O     1 
ATOM   2457 C CB    . LEU A 1 316 ? 192.970 183.316 213.317 1.00 59.44  ? 322 LEU J CB    1 
ATOM   2458 C CG    . LEU A 1 316 ? 192.319 184.218 214.358 1.00 59.44  ? 322 LEU J CG    1 
ATOM   2459 C CD1   . LEU A 1 316 ? 193.341 185.181 214.924 1.00 59.44  ? 322 LEU J CD1   1 
ATOM   2460 C CD2   . LEU A 1 316 ? 191.158 184.968 213.739 1.00 59.44  ? 322 LEU J CD2   1 
ATOM   2461 N N     . ALA A 1 317 ? 193.616 181.400 210.965 1.00 61.61  ? 323 ALA J N     1 
ATOM   2462 C CA    . ALA A 1 317 ? 194.190 181.236 209.642 1.00 61.61  ? 323 ALA J CA    1 
ATOM   2463 C C     . ALA A 1 317 ? 193.330 180.304 208.794 1.00 61.61  ? 323 ALA J C     1 
ATOM   2464 O O     . ALA A 1 317 ? 192.551 179.511 209.325 1.00 61.61  ? 323 ALA J O     1 
ATOM   2465 C CB    . ALA A 1 317 ? 195.611 180.690 209.750 1.00 61.61  ? 323 ALA J CB    1 
ATOM   2466 N N     . PRO A 1 318 ? 193.445 180.391 207.467 1.00 66.96  ? 324 PRO J N     1 
ATOM   2467 C CA    . PRO A 1 318 ? 192.676 179.496 206.597 1.00 66.96  ? 324 PRO J CA    1 
ATOM   2468 C C     . PRO A 1 318 ? 192.949 178.031 206.899 1.00 66.96  ? 324 PRO J C     1 
ATOM   2469 O O     . PRO A 1 318 ? 193.959 177.666 207.502 1.00 66.96  ? 324 PRO J O     1 
ATOM   2470 C CB    . PRO A 1 318 ? 193.159 179.876 205.196 1.00 66.96  ? 324 PRO J CB    1 
ATOM   2471 C CG    . PRO A 1 318 ? 193.521 181.306 205.331 1.00 66.96  ? 324 PRO J CG    1 
ATOM   2472 C CD    . PRO A 1 318 ? 194.146 181.425 206.689 1.00 66.96  ? 324 PRO J CD    1 
ATOM   2473 N N     . SER A 1 319 ? 192.025 177.182 206.460 1.00 71.03  ? 325 SER J N     1 
ATOM   2474 C CA    . SER A 1 319 ? 192.013 175.777 206.846 1.00 71.03  ? 325 SER J CA    1 
ATOM   2475 C C     . SER A 1 319 ? 193.005 174.923 206.067 1.00 71.03  ? 325 SER J C     1 
ATOM   2476 O O     . SER A 1 319 ? 192.930 173.693 206.147 1.00 71.03  ? 325 SER J O     1 
ATOM   2477 C CB    . SER A 1 319 ? 190.603 175.206 206.685 1.00 71.03  ? 325 SER J CB    1 
ATOM   2478 O OG    . SER A 1 319 ? 190.208 175.205 205.326 1.00 71.03  ? 325 SER J OG    1 
ATOM   2479 N N     . THR A 1 320 ? 193.924 175.532 205.323 1.00 69.15  ? 326 THR J N     1 
ATOM   2480 C CA    . THR A 1 320 ? 194.942 174.793 204.591 1.00 69.15  ? 326 THR J CA    1 
ATOM   2481 C C     . THR A 1 320 ? 196.341 174.988 205.147 1.00 69.15  ? 326 THR J C     1 
ATOM   2482 O O     . THR A 1 320 ? 197.179 174.095 205.009 1.00 69.15  ? 326 THR J O     1 
ATOM   2483 C CB    . THR A 1 320 ? 194.934 175.203 203.111 1.00 69.15  ? 326 THR J CB    1 
ATOM   2484 O OG1   . THR A 1 320 ? 193.591 175.182 202.614 1.00 69.15  ? 326 THR J OG1   1 
ATOM   2485 C CG2   . THR A 1 320 ? 195.777 174.252 202.279 1.00 69.15  ? 326 THR J CG2   1 
ATOM   2486 N N     . MET A 1 321 ? 196.604 176.119 205.792 1.00 67.89  ? 327 MET J N     1 
ATOM   2487 C CA    . MET A 1 321 ? 197.949 176.431 206.246 1.00 67.89  ? 327 MET J CA    1 
ATOM   2488 C C     . MET A 1 321 ? 198.339 175.570 207.440 1.00 67.89  ? 327 MET J C     1 
ATOM   2489 O O     . MET A 1 321 ? 197.537 175.309 208.339 1.00 67.89  ? 327 MET J O     1 
ATOM   2490 C CB    . MET A 1 321 ? 198.051 177.909 206.612 1.00 67.89  ? 327 MET J CB    1 
ATOM   2491 C CG    . MET A 1 321 ? 197.904 178.853 205.431 1.00 67.89  ? 327 MET J CG    1 
ATOM   2492 S SD    . MET A 1 321 ? 199.378 178.941 204.397 1.00 67.89  ? 327 MET J SD    1 
ATOM   2493 C CE    . MET A 1 321 ? 199.009 177.727 203.135 1.00 67.89  ? 327 MET J CE    1 
ATOM   2494 N N     . LYS A 1 322 ? 199.594 175.130 207.441 1.00 66.27  ? 328 LYS J N     1 
ATOM   2495 C CA    . LYS A 1 322 ? 200.149 174.351 208.541 1.00 66.27  ? 328 LYS J CA    1 
ATOM   2496 C C     . LYS A 1 322 ? 200.687 175.318 209.585 1.00 66.27  ? 328 LYS J C     1 
ATOM   2497 O O     . LYS A 1 322 ? 201.716 175.965 209.368 1.00 66.27  ? 328 LYS J O     1 
ATOM   2498 C CB    . LYS A 1 322 ? 201.250 173.417 208.047 1.00 66.27  ? 328 LYS J CB    1 
ATOM   2499 C CG    . LYS A 1 322 ? 200.817 172.455 206.959 1.00 66.27  ? 328 LYS J CG    1 
ATOM   2500 C CD    . LYS A 1 322 ? 199.860 171.406 207.495 1.00 66.27  ? 328 LYS J CD    1 
ATOM   2501 C CE    . LYS A 1 322 ? 199.261 170.586 206.369 1.00 66.27  ? 328 LYS J CE    1 
ATOM   2502 N NZ    . LYS A 1 322 ? 197.926 170.049 206.736 1.00 66.27  ? 328 LYS J NZ    1 
ATOM   2503 N N     . ILE A 1 323 ? 199.993 175.424 210.711 1.00 62.32  ? 329 ILE J N     1 
ATOM   2504 C CA    . ILE A 1 323 ? 200.422 176.281 211.809 1.00 62.32  ? 329 ILE J CA    1 
ATOM   2505 C C     . ILE A 1 323 ? 201.288 175.459 212.750 1.00 62.32  ? 329 ILE J C     1 
ATOM   2506 O O     . ILE A 1 323 ? 200.824 174.474 213.333 1.00 62.32  ? 329 ILE J O     1 
ATOM   2507 C CB    . ILE A 1 323 ? 199.221 176.881 212.552 1.00 62.32  ? 329 ILE J CB    1 
ATOM   2508 C CG1   . ILE A 1 323 ? 198.220 177.467 211.561 1.00 62.32  ? 329 ILE J CG1   1 
ATOM   2509 C CG2   . ILE A 1 323 ? 199.686 177.944 213.524 1.00 62.32  ? 329 ILE J CG2   1 
ATOM   2510 C CD1   . ILE A 1 323 ? 198.796 178.554 210.700 1.00 62.32  ? 329 ILE J CD1   1 
ATOM   2511 N N     . LYS A 1 324 ? 202.546 175.861 212.899 1.00 59.69  ? 330 LYS J N     1 
ATOM   2512 C CA    . LYS A 1 324 ? 203.488 175.198 213.789 1.00 59.69  ? 330 LYS J CA    1 
ATOM   2513 C C     . LYS A 1 324 ? 203.968 176.210 214.814 1.00 59.69  ? 330 LYS J C     1 
ATOM   2514 O O     . LYS A 1 324 ? 204.376 177.317 214.452 1.00 59.69  ? 330 LYS J O     1 
ATOM   2515 C CB    . LYS A 1 324 ? 204.671 174.620 213.015 1.00 59.69  ? 330 LYS J CB    1 
ATOM   2516 C CG    . LYS A 1 324 ? 204.304 173.486 212.079 1.00 59.69  ? 330 LYS J CG    1 
ATOM   2517 C CD    . LYS A 1 324 ? 203.889 172.243 212.846 1.00 59.69  ? 330 LYS J CD    1 
ATOM   2518 C CE    . LYS A 1 324 ? 203.604 171.090 211.900 1.00 59.69  ? 330 LYS J CE    1 
ATOM   2519 N NZ    . LYS A 1 324 ? 204.689 170.925 210.894 1.00 59.69  ? 330 LYS J NZ    1 
ATOM   2520 N N     . ILE A 1 325 ? 203.909 175.838 216.086 1.00 54.95  ? 331 ILE J N     1 
ATOM   2521 C CA    . ILE A 1 325 ? 204.393 176.677 217.173 1.00 54.95  ? 331 ILE J CA    1 
ATOM   2522 C C     . ILE A 1 325 ? 205.692 176.065 217.672 1.00 54.95  ? 331 ILE J C     1 
ATOM   2523 O O     . ILE A 1 325 ? 205.701 174.956 218.214 1.00 54.95  ? 331 ILE J O     1 
ATOM   2524 C CB    . ILE A 1 325 ? 203.363 176.798 218.300 1.00 54.95  ? 331 ILE J CB    1 
ATOM   2525 C CG1   . ILE A 1 325 ? 202.047 177.344 217.757 1.00 54.95  ? 331 ILE J CG1   1 
ATOM   2526 C CG2   . ILE A 1 325 ? 203.884 177.708 219.386 1.00 54.95  ? 331 ILE J CG2   1 
ATOM   2527 C CD1   . ILE A 1 325 ? 202.153 178.737 217.202 1.00 54.95  ? 331 ILE J CD1   1 
ATOM   2528 N N     . ILE A 1 326 ? 206.793 176.782 217.485 1.00 54.10  ? 332 ILE J N     1 
ATOM   2529 C CA    . ILE A 1 326 ? 208.105 176.313 217.909 1.00 54.10  ? 332 ILE J CA    1 
ATOM   2530 C C     . ILE A 1 326 ? 208.326 176.805 219.333 1.00 54.10  ? 332 ILE J C     1 
ATOM   2531 O O     . ILE A 1 326 ? 208.445 178.008 219.572 1.00 54.10  ? 332 ILE J O     1 
ATOM   2532 C CB    . ILE A 1 326 ? 209.208 176.808 216.969 1.00 54.10  ? 332 ILE J CB    1 
ATOM   2533 C CG1   . ILE A 1 326 ? 208.894 176.399 215.530 1.00 54.10  ? 332 ILE J CG1   1 
ATOM   2534 C CG2   . ILE A 1 326 ? 210.551 176.260 217.396 1.00 54.10  ? 332 ILE J CG2   1 
ATOM   2535 C CD1   . ILE A 1 326 ? 208.772 174.914 215.329 1.00 54.10  ? 332 ILE J CD1   1 
ATOM   2536 N N     . ALA A 1 327 ? 208.380 175.874 220.282 1.00 55.30  ? 333 ALA J N     1 
ATOM   2537 C CA    . ALA A 1 327 ? 208.499 176.199 221.700 1.00 55.30  ? 333 ALA J CA    1 
ATOM   2538 C C     . ALA A 1 327 ? 209.643 175.396 222.299 1.00 55.30  ? 333 ALA J C     1 
ATOM   2539 O O     . ALA A 1 327 ? 209.433 174.299 222.835 1.00 55.30  ? 333 ALA J O     1 
ATOM   2540 C CB    . ALA A 1 327 ? 207.194 175.922 222.439 1.00 55.30  ? 333 ALA J CB    1 
ATOM   2541 N N     . PRO A 1 328 ? 210.872 175.910 222.228 1.00 54.51  ? 334 PRO J N     1 
ATOM   2542 C CA    . PRO A 1 328 ? 211.992 175.188 222.817 1.00 54.51  ? 334 PRO J CA    1 
ATOM   2543 C C     . PRO A 1 328 ? 211.913 175.224 224.331 1.00 54.51  ? 334 PRO J C     1 
ATOM   2544 O O     . PRO A 1 328 ? 211.381 176.183 224.915 1.00 54.51  ? 334 PRO J O     1 
ATOM   2545 C CB    . PRO A 1 328 ? 213.221 175.960 222.302 1.00 54.51  ? 334 PRO J CB    1 
ATOM   2546 C CG    . PRO A 1 328 ? 212.707 176.859 221.219 1.00 54.51  ? 334 PRO J CG    1 
ATOM   2547 C CD    . PRO A 1 328 ? 211.298 177.154 221.573 1.00 54.51  ? 334 PRO J CD    1 
ATOM   2548 N N     . PRO A 1 329 ? 212.425 174.199 225.014 1.00 58.24  ? 335 PRO J N     1 
ATOM   2549 C CA    . PRO A 1 329 ? 212.388 174.206 226.483 1.00 58.24  ? 335 PRO J CA    1 
ATOM   2550 C C     . PRO A 1 329 ? 213.306 175.237 227.115 1.00 58.24  ? 335 PRO J C     1 
ATOM   2551 O O     . PRO A 1 329 ? 213.204 175.464 228.327 1.00 58.24  ? 335 PRO J O     1 
ATOM   2552 C CB    . PRO A 1 329 ? 212.819 172.781 226.854 1.00 58.24  ? 335 PRO J CB    1 
ATOM   2553 C CG    . PRO A 1 329 ? 213.550 172.281 225.662 1.00 58.24  ? 335 PRO J CG    1 
ATOM   2554 C CD    . PRO A 1 329 ? 212.918 172.922 224.474 1.00 58.24  ? 335 PRO J CD    1 
ATOM   2555 N N     . GLU A 1 330 ? 214.188 175.871 226.345 1.00 58.21  ? 336 GLU J N     1 
ATOM   2556 C CA    . GLU A 1 330 ? 215.093 176.887 226.864 1.00 58.21  ? 336 GLU J CA    1 
ATOM   2557 C C     . GLU A 1 330 ? 214.793 178.270 226.297 1.00 58.21  ? 336 GLU J C     1 
ATOM   2558 O O     . GLU A 1 330 ? 215.653 179.154 226.339 1.00 58.21  ? 336 GLU J O     1 
ATOM   2559 C CB    . GLU A 1 330 ? 216.545 176.490 226.586 1.00 58.21  ? 336 GLU J CB    1 
ATOM   2560 C CG    . GLU A 1 330 ? 217.043 176.777 225.175 1.00 58.21  ? 336 GLU J CG    1 
ATOM   2561 C CD    . GLU A 1 330 ? 216.652 175.705 224.177 1.00 58.21  ? 336 GLU J CD    1 
ATOM   2562 O OE1   . GLU A 1 330 ? 215.969 174.739 224.573 1.00 58.21  ? 336 GLU J OE1   1 
ATOM   2563 O OE2   . GLU A 1 330 ? 217.028 175.829 222.992 1.00 58.21  ? 336 GLU J OE2   1 
ATOM   2564 N N     . ARG A 1 331 ? 213.571 178.488 225.805 1.00 52.07  ? 337 ARG J N     1 
ATOM   2565 C CA    . ARG A 1 331 ? 213.237 179.737 225.130 1.00 52.07  ? 337 ARG J CA    1 
ATOM   2566 C C     . ARG A 1 331 ? 213.367 180.962 226.023 1.00 52.07  ? 337 ARG J C     1 
ATOM   2567 O O     . ARG A 1 331 ? 213.265 182.083 225.517 1.00 52.07  ? 337 ARG J O     1 
ATOM   2568 C CB    . ARG A 1 331 ? 211.820 179.670 224.562 1.00 52.07  ? 337 ARG J CB    1 
ATOM   2569 C CG    . ARG A 1 331 ? 210.735 179.328 225.562 1.00 52.07  ? 337 ARG J CG    1 
ATOM   2570 C CD    . ARG A 1 331 ? 209.464 178.965 224.823 1.00 52.07  ? 337 ARG J CD    1 
ATOM   2571 N NE    . ARG A 1 331 ? 208.343 178.664 225.704 1.00 52.07  ? 337 ARG J NE    1 
ATOM   2572 C CZ    . ARG A 1 331 ? 208.011 177.442 226.095 1.00 52.07  ? 337 ARG J CZ    1 
ATOM   2573 N NH1   . ARG A 1 331 ? 208.718 176.400 225.692 1.00 52.07  ? 337 ARG J NH1   1 
ATOM   2574 N NH2   . ARG A 1 331 ? 206.970 177.259 226.891 1.00 52.07  ? 337 ARG J NH2   1 
ATOM   2575 N N     . LYS A 1 332 ? 213.591 180.789 227.323 1.00 54.27  ? 338 LYS J N     1 
ATOM   2576 C CA    . LYS A 1 332 ? 213.763 181.940 228.195 1.00 54.27  ? 338 LYS J CA    1 
ATOM   2577 C C     . LYS A 1 332 ? 215.087 182.652 227.954 1.00 54.27  ? 338 LYS J C     1 
ATOM   2578 O O     . LYS A 1 332 ? 215.210 183.835 228.284 1.00 54.27  ? 338 LYS J O     1 
ATOM   2579 C CB    . LYS A 1 332 ? 213.649 181.503 229.655 1.00 54.27  ? 338 LYS J CB    1 
ATOM   2580 C CG    . LYS A 1 332 ? 213.583 182.643 230.646 1.00 54.27  ? 338 LYS J CG    1 
ATOM   2581 C CD    . LYS A 1 332 ? 213.495 182.139 232.069 1.00 54.27  ? 338 LYS J CD    1 
ATOM   2582 C CE    . LYS A 1 332 ? 213.675 183.276 233.058 1.00 54.27  ? 338 LYS J CE    1 
ATOM   2583 N NZ    . LYS A 1 332 ? 213.681 182.792 234.461 1.00 54.27  ? 338 LYS J NZ    1 
ATOM   2584 N N     . TYR A 1 333 ? 216.073 181.969 227.368 1.00 54.36  ? 339 TYR J N     1 
ATOM   2585 C CA    . TYR A 1 333 ? 217.392 182.546 227.127 1.00 54.36  ? 339 TYR J CA    1 
ATOM   2586 C C     . TYR A 1 333 ? 217.742 182.582 225.645 1.00 54.36  ? 339 TYR J C     1 
ATOM   2587 O O     . TYR A 1 333 ? 218.927 182.635 225.295 1.00 54.36  ? 339 TYR J O     1 
ATOM   2588 C CB    . TYR A 1 333 ? 218.460 181.771 227.899 1.00 54.36  ? 339 TYR J CB    1 
ATOM   2589 C CG    . TYR A 1 333 ? 218.112 181.531 229.344 1.00 54.36  ? 339 TYR J CG    1 
ATOM   2590 C CD1   . TYR A 1 333 ? 218.337 182.504 230.302 1.00 54.36  ? 339 TYR J CD1   1 
ATOM   2591 C CD2   . TYR A 1 333 ? 217.553 180.333 229.750 1.00 54.36  ? 339 TYR J CD2   1 
ATOM   2592 C CE1   . TYR A 1 333 ? 218.017 182.289 231.618 1.00 54.36  ? 339 TYR J CE1   1 
ATOM   2593 C CE2   . TYR A 1 333 ? 217.230 180.110 231.064 1.00 54.36  ? 339 TYR J CE2   1 
ATOM   2594 C CZ    . TYR A 1 333 ? 217.462 181.091 231.994 1.00 54.36  ? 339 TYR J CZ    1 
ATOM   2595 O OH    . TYR A 1 333 ? 217.142 180.871 233.310 1.00 54.36  ? 339 TYR J OH    1 
ATOM   2596 N N     . SER A 1 334 ? 216.737 182.542 224.768 1.00 51.91  ? 340 SER J N     1 
ATOM   2597 C CA    . SER A 1 334 ? 217.008 182.515 223.336 1.00 51.91  ? 340 SER J CA    1 
ATOM   2598 C C     . SER A 1 334 ? 217.686 183.795 222.877 1.00 51.91  ? 340 SER J C     1 
ATOM   2599 O O     . SER A 1 334 ? 218.562 183.762 222.008 1.00 51.91  ? 340 SER J O     1 
ATOM   2600 C CB    . SER A 1 334 ? 215.716 182.291 222.555 1.00 51.91  ? 340 SER J CB    1 
ATOM   2601 O OG    . SER A 1 334 ? 215.188 181.006 222.810 1.00 51.91  ? 340 SER J OG    1 
ATOM   2602 N N     . VAL A 1 335 ? 217.301 184.934 223.451 1.00 51.02  ? 341 VAL J N     1 
ATOM   2603 C CA    . VAL A 1 335 ? 217.903 186.200 223.047 1.00 51.02  ? 341 VAL J CA    1 
ATOM   2604 C C     . VAL A 1 335 ? 219.396 186.193 223.342 1.00 51.02  ? 341 VAL J C     1 
ATOM   2605 O O     . VAL A 1 335 ? 220.214 186.578 222.501 1.00 51.02  ? 341 VAL J O     1 
ATOM   2606 C CB    . VAL A 1 335 ? 217.194 187.377 223.736 1.00 51.02  ? 341 VAL J CB    1 
ATOM   2607 C CG1   . VAL A 1 335 ? 217.827 188.690 223.321 1.00 51.02  ? 341 VAL J CG1   1 
ATOM   2608 C CG2   . VAL A 1 335 ? 215.716 187.366 223.399 1.00 51.02  ? 341 VAL J CG2   1 
ATOM   2609 N N     . TRP A 1 336 ? 219.777 185.721 224.529 1.00 52.53  ? 342 TRP J N     1 
ATOM   2610 C CA    . TRP A 1 336 ? 221.193 185.682 224.875 1.00 52.53  ? 342 TRP J CA    1 
ATOM   2611 C C     . TRP A 1 336 ? 221.944 184.655 224.037 1.00 52.53  ? 342 TRP J C     1 
ATOM   2612 O O     . TRP A 1 336 ? 223.076 184.908 223.607 1.00 52.53  ? 342 TRP J O     1 
ATOM   2613 C CB    . TRP A 1 336 ? 221.378 185.386 226.362 1.00 52.53  ? 342 TRP J CB    1 
ATOM   2614 C CG    . TRP A 1 336 ? 222.776 185.642 226.799 1.00 52.53  ? 342 TRP J CG    1 
ATOM   2615 C CD1   . TRP A 1 336 ? 223.255 186.777 227.371 1.00 52.53  ? 342 TRP J CD1   1 
ATOM   2616 C CD2   . TRP A 1 336 ? 223.892 184.760 226.661 1.00 52.53  ? 342 TRP J CD2   1 
ATOM   2617 N NE1   . TRP A 1 336 ? 224.596 186.654 227.613 1.00 52.53  ? 342 TRP J NE1   1 
ATOM   2618 C CE2   . TRP A 1 336 ? 225.012 185.422 227.186 1.00 52.53  ? 342 TRP J CE2   1 
ATOM   2619 C CE3   . TRP A 1 336 ? 224.052 183.470 226.154 1.00 52.53  ? 342 TRP J CE3   1 
ATOM   2620 C CZ2   . TRP A 1 336 ? 226.269 184.844 227.215 1.00 52.53  ? 342 TRP J CZ2   1 
ATOM   2621 C CZ3   . TRP A 1 336 ? 225.297 182.902 226.182 1.00 52.53  ? 342 TRP J CZ3   1 
ATOM   2622 C CH2   . TRP A 1 336 ? 226.390 183.586 226.709 1.00 52.53  ? 342 TRP J CH2   1 
ATOM   2623 N N     . ILE A 1 337 ? 221.351 183.479 223.822 1.00 50.61  ? 343 ILE J N     1 
ATOM   2624 C CA    . ILE A 1 337 ? 222.018 182.459 223.017 1.00 50.61  ? 343 ILE J CA    1 
ATOM   2625 C C     . ILE A 1 337 ? 222.290 182.988 221.615 1.00 50.61  ? 343 ILE J C     1 
ATOM   2626 O O     . ILE A 1 337 ? 223.401 182.858 221.082 1.00 50.61  ? 343 ILE J O     1 
ATOM   2627 C CB    . ILE A 1 337 ? 221.182 181.169 222.985 1.00 50.61  ? 343 ILE J CB    1 
ATOM   2628 C CG1   . ILE A 1 337 ? 221.114 180.552 224.378 1.00 50.61  ? 343 ILE J CG1   1 
ATOM   2629 C CG2   . ILE A 1 337 ? 221.768 180.179 222.004 1.00 50.61  ? 343 ILE J CG2   1 
ATOM   2630 C CD1   . ILE A 1 337 ? 220.301 179.295 224.436 1.00 50.61  ? 343 ILE J CD1   1 
ATOM   2631 N N     . GLY A 1 338 ? 221.283 183.608 221.001 1.00 50.01  ? 344 GLY J N     1 
ATOM   2632 C CA    . GLY A 1 338 ? 221.477 184.193 219.691 1.00 50.01  ? 344 GLY J CA    1 
ATOM   2633 C C     . GLY A 1 338 ? 222.463 185.340 219.687 1.00 50.01  ? 344 GLY J C     1 
ATOM   2634 O O     . GLY A 1 338 ? 223.197 185.523 218.716 1.00 50.01  ? 344 GLY J O     1 
ATOM   2635 N N     . GLY A 1 339 ? 222.508 186.119 220.767 1.00 49.84  ? 345 GLY J N     1 
ATOM   2636 C CA    . GLY A 1 339 ? 223.483 187.192 220.839 1.00 49.84  ? 345 GLY J CA    1 
ATOM   2637 C C     . GLY A 1 339 ? 224.906 186.677 220.896 1.00 49.84  ? 345 GLY J C     1 
ATOM   2638 O O     . GLY A 1 339 ? 225.805 187.246 220.272 1.00 49.84  ? 345 GLY J O     1 
ATOM   2639 N N     . SER A 1 340 ? 225.129 185.584 221.626 1.00 51.09  ? 346 SER J N     1 
ATOM   2640 C CA    . SER A 1 340 ? 226.466 184.998 221.663 1.00 51.09  ? 346 SER J CA    1 
ATOM   2641 C C     . SER A 1 340 ? 226.829 184.388 220.316 1.00 51.09  ? 346 SER J C     1 
ATOM   2642 O O     . SER A 1 340 ? 227.968 184.524 219.852 1.00 51.09  ? 346 SER J O     1 
ATOM   2643 C CB    . SER A 1 340 ? 226.563 183.946 222.764 1.00 51.09  ? 346 SER J CB    1 
ATOM   2644 O OG    . SER A 1 340 ? 225.800 182.803 222.435 1.00 51.09  ? 346 SER J OG    1 
ATOM   2645 N N     . ILE A 1 341 ? 225.871 183.720 219.669 1.00 50.46  ? 347 ILE J N     1 
ATOM   2646 C CA    . ILE A 1 341 ? 226.121 183.197 218.329 1.00 50.46  ? 347 ILE J CA    1 
ATOM   2647 C C     . ILE A 1 341 ? 226.507 184.324 217.380 1.00 50.46  ? 347 ILE J C     1 
ATOM   2648 O O     . ILE A 1 341 ? 227.462 184.202 216.606 1.00 50.46  ? 347 ILE J O     1 
ATOM   2649 C CB    . ILE A 1 341 ? 224.897 182.419 217.814 1.00 50.46  ? 347 ILE J CB    1 
ATOM   2650 C CG1   . ILE A 1 341 ? 224.779 181.078 218.530 1.00 50.46  ? 347 ILE J CG1   1 
ATOM   2651 C CG2   . ILE A 1 341 ? 225.002 182.194 216.323 1.00 50.46  ? 347 ILE J CG2   1 
ATOM   2652 C CD1   . ILE A 1 341 ? 223.626 180.238 218.051 1.00 50.46  ? 347 ILE J CD1   1 
ATOM   2653 N N     . LEU A 1 342 ? 225.781 185.441 217.430 1.00 49.22  ? 348 LEU J N     1 
ATOM   2654 C CA    . LEU A 1 342 ? 226.065 186.555 216.531 1.00 49.22  ? 348 LEU J CA    1 
ATOM   2655 C C     . LEU A 1 342 ? 227.423 187.176 216.827 1.00 49.22  ? 348 LEU J C     1 
ATOM   2656 O O     . LEU A 1 342 ? 228.192 187.473 215.909 1.00 49.22  ? 348 LEU J O     1 
ATOM   2657 C CB    . LEU A 1 342 ? 224.961 187.607 216.630 1.00 49.22  ? 348 LEU J CB    1 
ATOM   2658 C CG    . LEU A 1 342 ? 225.212 188.893 215.845 1.00 49.22  ? 348 LEU J CG    1 
ATOM   2659 C CD1   . LEU A 1 342 ? 225.083 188.645 214.359 1.00 49.22  ? 348 LEU J CD1   1 
ATOM   2660 C CD2   . LEU A 1 342 ? 224.272 189.997 216.285 1.00 49.22  ? 348 LEU J CD2   1 
ATOM   2661 N N     . ALA A 1 343 ? 227.737 187.385 218.105 1.00 50.56  ? 349 ALA J N     1 
ATOM   2662 C CA    . ALA A 1 343 ? 229.021 187.973 218.457 1.00 50.56  ? 349 ALA J CA    1 
ATOM   2663 C C     . ALA A 1 343 ? 230.187 187.023 218.236 1.00 50.56  ? 349 ALA J C     1 
ATOM   2664 O O     . ALA A 1 343 ? 231.338 187.466 218.288 1.00 50.56  ? 349 ALA J O     1 
ATOM   2665 C CB    . ALA A 1 343 ? 229.006 188.442 219.910 1.00 50.56  ? 349 ALA J CB    1 
ATOM   2666 N N     . SER A 1 344 ? 229.927 185.737 218.004 1.00 53.55  ? 350 SER J N     1 
ATOM   2667 C CA    . SER A 1 344 ? 230.993 184.802 217.674 1.00 53.55  ? 350 SER J CA    1 
ATOM   2668 C C     . SER A 1 344 ? 231.328 184.762 216.189 1.00 53.55  ? 350 SER J C     1 
ATOM   2669 O O     . SER A 1 344 ? 232.432 184.337 215.833 1.00 53.55  ? 350 SER J O     1 
ATOM   2670 C CB    . SER A 1 344 ? 230.623 183.390 218.136 1.00 53.55  ? 350 SER J CB    1 
ATOM   2671 O OG    . SER A 1 344 ? 230.705 183.276 219.543 1.00 53.55  ? 350 SER J OG    1 
ATOM   2672 N N     . LEU A 1 345 ? 230.409 185.183 215.321 1.00 54.48  ? 351 LEU J N     1 
ATOM   2673 C CA    . LEU A 1 345 ? 230.624 185.081 213.883 1.00 54.48  ? 351 LEU J CA    1 
ATOM   2674 C C     . LEU A 1 345 ? 231.821 185.913 213.446 1.00 54.48  ? 351 LEU J C     1 
ATOM   2675 O O     . LEU A 1 345 ? 232.058 187.009 213.958 1.00 54.48  ? 351 LEU J O     1 
ATOM   2676 C CB    . LEU A 1 345 ? 229.381 185.533 213.123 1.00 54.48  ? 351 LEU J CB    1 
ATOM   2677 C CG    . LEU A 1 345 ? 228.109 184.708 213.303 1.00 54.48  ? 351 LEU J CG    1 
ATOM   2678 C CD1   . LEU A 1 345 ? 226.983 185.307 212.491 1.00 54.48  ? 351 LEU J CD1   1 
ATOM   2679 C CD2   . LEU A 1 345 ? 228.348 183.273 212.903 1.00 54.48  ? 351 LEU J CD2   1 
ATOM   2680 N N     . SER A 1 346 ? 232.578 185.381 212.486 1.00 58.86  ? 352 SER J N     1 
ATOM   2681 C CA    . SER A 1 346 ? 233.736 186.103 211.973 1.00 58.86  ? 352 SER J CA    1 
ATOM   2682 C C     . SER A 1 346 ? 233.313 187.279 211.106 1.00 58.86  ? 352 SER J C     1 
ATOM   2683 O O     . SER A 1 346 ? 233.940 188.343 211.142 1.00 58.86  ? 352 SER J O     1 
ATOM   2684 C CB    . SER A 1 346 ? 234.636 185.155 211.185 1.00 58.86  ? 352 SER J CB    1 
ATOM   2685 O OG    . SER A 1 346 ? 234.916 183.987 211.935 1.00 58.86  ? 352 SER J OG    1 
ATOM   2686 N N     . THR A 1 347 ? 232.250 187.110 210.324 1.00 58.75  ? 353 THR J N     1 
ATOM   2687 C CA    . THR A 1 347 ? 231.758 188.180 209.468 1.00 58.75  ? 353 THR J CA    1 
ATOM   2688 C C     . THR A 1 347 ? 231.141 189.331 210.245 1.00 58.75  ? 353 THR J C     1 
ATOM   2689 O O     . THR A 1 347 ? 230.773 190.335 209.629 1.00 58.75  ? 353 THR J O     1 
ATOM   2690 C CB    . THR A 1 347 ? 230.735 187.629 208.478 1.00 58.75  ? 353 THR J CB    1 
ATOM   2691 O OG1   . THR A 1 347 ? 230.337 188.669 207.578 1.00 58.75  ? 353 THR J OG1   1 
ATOM   2692 C CG2   . THR A 1 347 ? 229.520 187.115 209.209 1.00 58.75  ? 353 THR J CG2   1 
ATOM   2693 N N     . PHE A 1 348 ? 231.014 189.217 211.565 1.00 56.23  ? 354 PHE J N     1 
ATOM   2694 C CA    . PHE A 1 348 ? 230.446 190.283 212.376 1.00 56.23  ? 354 PHE J CA    1 
ATOM   2695 C C     . PHE A 1 348 ? 231.499 191.220 212.946 1.00 56.23  ? 354 PHE J C     1 
ATOM   2696 O O     . PHE A 1 348 ? 231.167 192.353 213.310 1.00 56.23  ? 354 PHE J O     1 
ATOM   2697 C CB    . PHE A 1 348 ? 229.616 189.685 213.516 1.00 56.23  ? 354 PHE J CB    1 
ATOM   2698 C CG    . PHE A 1 348 ? 229.065 190.704 214.468 1.00 56.23  ? 354 PHE J CG    1 
ATOM   2699 C CD1   . PHE A 1 348 ? 227.957 191.455 214.131 1.00 56.23  ? 354 PHE J CD1   1 
ATOM   2700 C CD2   . PHE A 1 348 ? 229.649 190.905 215.703 1.00 56.23  ? 354 PHE J CD2   1 
ATOM   2701 C CE1   . PHE A 1 348 ? 227.447 192.389 215.002 1.00 56.23  ? 354 PHE J CE1   1 
ATOM   2702 C CE2   . PHE A 1 348 ? 229.141 191.837 216.575 1.00 56.23  ? 354 PHE J CE2   1 
ATOM   2703 C CZ    . PHE A 1 348 ? 228.038 192.579 216.224 1.00 56.23  ? 354 PHE J CZ    1 
ATOM   2704 N N     . GLN A 1 349 ? 232.760 190.794 213.005 1.00 57.84  ? 355 GLN J N     1 
ATOM   2705 C CA    . GLN A 1 349 ? 233.820 191.597 213.602 1.00 57.84  ? 355 GLN J CA    1 
ATOM   2706 C C     . GLN A 1 349 ? 234.093 192.867 212.805 1.00 57.84  ? 355 GLN J C     1 
ATOM   2707 O O     . GLN A 1 349 ? 234.950 193.671 213.184 1.00 57.84  ? 355 GLN J O     1 
ATOM   2708 C CB    . GLN A 1 349 ? 235.099 190.770 213.734 1.00 57.84  ? 355 GLN J CB    1 
ATOM   2709 C CG    . GLN A 1 349 ? 234.892 189.414 214.384 1.00 57.84  ? 355 GLN J CG    1 
ATOM   2710 C CD    . GLN A 1 349 ? 234.119 189.500 215.685 1.00 57.84  ? 355 GLN J CD    1 
ATOM   2711 O OE1   . GLN A 1 349 ? 233.097 188.841 215.856 1.00 57.84  ? 355 GLN J OE1   1 
ATOM   2712 N NE2   . GLN A 1 349 ? 234.611 190.308 216.614 1.00 57.84  ? 355 GLN J NE2   1 
ATOM   2713 N N     . GLN A 1 350 ? 233.375 193.055 211.703 1.00 61.10  ? 356 GLN J N     1 
ATOM   2714 C CA    . GLN A 1 350 ? 233.425 194.288 210.935 1.00 61.10  ? 356 GLN J CA    1 
ATOM   2715 C C     . GLN A 1 350 ? 232.264 195.218 211.250 1.00 61.10  ? 356 GLN J C     1 
ATOM   2716 O O     . GLN A 1 350 ? 232.216 196.329 210.717 1.00 61.10  ? 356 GLN J O     1 
ATOM   2717 C CB    . GLN A 1 350 ? 233.441 193.978 209.436 1.00 61.10  ? 356 GLN J CB    1 
ATOM   2718 C CG    . GLN A 1 350 ? 234.798 193.556 208.895 1.00 61.10  ? 356 GLN J CG    1 
ATOM   2719 C CD    . GLN A 1 350 ? 235.160 192.131 209.267 1.00 61.10  ? 356 GLN J CD    1 
ATOM   2720 O OE1   . GLN A 1 350 ? 236.288 191.850 209.674 1.00 61.10  ? 356 GLN J OE1   1 
ATOM   2721 N NE2   . GLN A 1 350 ? 234.201 191.222 209.128 1.00 61.10  ? 356 GLN J NE2   1 
ATOM   2722 N N     . MET A 1 351 ? 231.333 194.793 212.104 1.00 59.92  ? 357 MET J N     1 
ATOM   2723 C CA    . MET A 1 351 ? 230.126 195.554 212.385 1.00 59.92  ? 357 MET J CA    1 
ATOM   2724 C C     . MET A 1 351 ? 230.183 196.326 213.695 1.00 59.92  ? 357 MET J C     1 
ATOM   2725 O O     . MET A 1 351 ? 229.277 197.120 213.959 1.00 59.92  ? 357 MET J O     1 
ATOM   2726 C CB    . MET A 1 351 ? 228.909 194.625 212.410 1.00 59.92  ? 357 MET J CB    1 
ATOM   2727 C CG    . MET A 1 351 ? 228.852 193.650 211.256 1.00 59.92  ? 357 MET J CG    1 
ATOM   2728 S SD    . MET A 1 351 ? 228.051 194.333 209.799 1.00 59.92  ? 357 MET J SD    1 
ATOM   2729 C CE    . MET A 1 351 ? 228.330 193.012 208.626 1.00 59.92  ? 357 MET J CE    1 
ATOM   2730 N N     . TRP A 1 352 ? 231.202 196.109 214.521 1.00 57.45  ? 358 TRP J N     1 
ATOM   2731 C CA    . TRP A 1 352 ? 231.301 196.835 215.778 1.00 57.45  ? 358 TRP J CA    1 
ATOM   2732 C C     . TRP A 1 352 ? 231.404 198.334 215.532 1.00 57.45  ? 358 TRP J C     1 
ATOM   2733 O O     . TRP A 1 352 ? 231.931 198.787 214.514 1.00 57.45  ? 358 TRP J O     1 
ATOM   2734 C CB    . TRP A 1 352 ? 232.520 196.379 216.576 1.00 57.45  ? 358 TRP J CB    1 
ATOM   2735 C CG    . TRP A 1 352 ? 232.516 194.948 216.965 1.00 57.45  ? 358 TRP J CG    1 
ATOM   2736 C CD1   . TRP A 1 352 ? 233.235 193.949 216.393 1.00 57.45  ? 358 TRP J CD1   1 
ATOM   2737 C CD2   . TRP A 1 352 ? 231.779 194.350 218.035 1.00 57.45  ? 358 TRP J CD2   1 
ATOM   2738 N NE1   . TRP A 1 352 ? 232.986 192.762 217.030 1.00 57.45  ? 358 TRP J NE1   1 
ATOM   2739 C CE2   . TRP A 1 352 ? 232.093 192.982 218.043 1.00 57.45  ? 358 TRP J CE2   1 
ATOM   2740 C CE3   . TRP A 1 352 ? 230.879 194.838 218.982 1.00 57.45  ? 358 TRP J CE3   1 
ATOM   2741 C CZ2   . TRP A 1 352 ? 231.542 192.098 218.959 1.00 57.45  ? 358 TRP J CZ2   1 
ATOM   2742 C CZ3   . TRP A 1 352 ? 230.334 193.959 219.889 1.00 57.45  ? 358 TRP J CZ3   1 
ATOM   2743 C CH2   . TRP A 1 352 ? 230.667 192.606 219.871 1.00 57.45  ? 358 TRP J CH2   1 
ATOM   2744 N N     . ILE A 1 353 ? 230.893 199.107 216.482 1.00 63.14  ? 359 ILE J N     1 
ATOM   2745 C CA    . ILE A 1 353 ? 231.067 200.552 216.506 1.00 63.14  ? 359 ILE J CA    1 
ATOM   2746 C C     . ILE A 1 353 ? 232.327 200.814 217.317 1.00 63.14  ? 359 ILE J C     1 
ATOM   2747 O O     . ILE A 1 353 ? 232.288 200.843 218.547 1.00 63.14  ? 359 ILE J O     1 
ATOM   2748 C CB    . ILE A 1 353 ? 229.853 201.266 217.104 1.00 63.14  ? 359 ILE J CB    1 
ATOM   2749 C CG1   . ILE A 1 353 ? 228.570 200.815 216.414 1.00 63.14  ? 359 ILE J CG1   1 
ATOM   2750 C CG2   . ILE A 1 353 ? 230.010 202.768 216.986 1.00 63.14  ? 359 ILE J CG2   1 
ATOM   2751 C CD1   . ILE A 1 353 ? 227.332 201.483 216.959 1.00 63.14  ? 359 ILE J CD1   1 
ATOM   2752 N N     . SER A 1 354 ? 233.453 200.990 216.635 1.00 68.75  ? 360 SER J N     1 
ATOM   2753 C CA    . SER A 1 354 ? 234.713 201.194 217.331 1.00 68.75  ? 360 SER J CA    1 
ATOM   2754 C C     . SER A 1 354 ? 234.740 202.556 218.014 1.00 68.75  ? 360 SER J C     1 
ATOM   2755 O O     . SER A 1 354 ? 234.104 203.514 217.567 1.00 68.75  ? 360 SER J O     1 
ATOM   2756 C CB    . SER A 1 354 ? 235.884 201.072 216.361 1.00 68.75  ? 360 SER J CB    1 
ATOM   2757 O OG    . SER A 1 354 ? 235.719 201.939 215.255 1.00 68.75  ? 360 SER J OG    1 
ATOM   2758 N N     . LYS A 1 355 ? 235.485 202.628 219.121 1.00 70.01  ? 361 LYS J N     1 
ATOM   2759 C CA    . LYS A 1 355 ? 235.591 203.871 219.881 1.00 70.01  ? 361 LYS J CA    1 
ATOM   2760 C C     . LYS A 1 355 ? 236.080 205.021 219.014 1.00 70.01  ? 361 LYS J C     1 
ATOM   2761 O O     . LYS A 1 355 ? 235.676 206.172 219.220 1.00 70.01  ? 361 LYS J O     1 
ATOM   2762 C CB    . LYS A 1 355 ? 236.522 203.668 221.077 1.00 70.01  ? 361 LYS J CB    1 
ATOM   2763 C CG    . LYS A 1 355 ? 237.109 204.945 221.660 1.00 70.01  ? 361 LYS J CG    1 
ATOM   2764 C CD    . LYS A 1 355 ? 236.076 205.737 222.444 1.00 70.01  ? 361 LYS J CD    1 
ATOM   2765 C CE    . LYS A 1 355 ? 236.744 206.786 223.315 1.00 70.01  ? 361 LYS J CE    1 
ATOM   2766 N NZ    . LYS A 1 355 ? 235.767 207.729 223.922 1.00 70.01  ? 361 LYS J NZ    1 
ATOM   2767 N N     . GLN A 1 356 ? 236.938 204.733 218.036 1.00 76.59  ? 362 GLN J N     1 
ATOM   2768 C CA    . GLN A 1 356 ? 237.400 205.779 217.134 1.00 76.59  ? 362 GLN J CA    1 
ATOM   2769 C C     . GLN A 1 356 ? 236.246 206.356 216.325 1.00 76.59  ? 362 GLN J C     1 
ATOM   2770 O O     . GLN A 1 356 ? 236.151 207.576 216.148 1.00 76.59  ? 362 GLN J O     1 
ATOM   2771 C CB    . GLN A 1 356 ? 238.488 205.226 216.218 1.00 76.59  ? 362 GLN J CB    1 
ATOM   2772 C CG    . GLN A 1 356 ? 239.138 206.260 215.327 1.00 76.59  ? 362 GLN J CG    1 
ATOM   2773 C CD    . GLN A 1 356 ? 238.726 206.112 213.880 1.00 76.59  ? 362 GLN J CD    1 
ATOM   2774 O OE1   . GLN A 1 356 ? 238.017 205.174 213.518 1.00 76.59  ? 362 GLN J OE1   1 
ATOM   2775 N NE2   . GLN A 1 356 ? 239.175 207.036 213.040 1.00 76.59  ? 362 GLN J NE2   1 
ATOM   2776 N N     . GLU A 1 357 ? 235.349 205.497 215.837 1.00 74.61  ? 363 GLU J N     1 
ATOM   2777 C CA    . GLU A 1 357 ? 234.180 205.987 215.114 1.00 74.61  ? 363 GLU J CA    1 
ATOM   2778 C C     . GLU A 1 357 ? 233.314 206.867 216.002 1.00 74.61  ? 363 GLU J C     1 
ATOM   2779 O O     . GLU A 1 357 ? 232.761 207.872 215.542 1.00 74.61  ? 363 GLU J O     1 
ATOM   2780 C CB    . GLU A 1 357 ? 233.363 204.818 214.572 1.00 74.61  ? 363 GLU J CB    1 
ATOM   2781 C CG    . GLU A 1 357 ? 234.056 204.024 213.491 1.00 74.61  ? 363 GLU J CG    1 
ATOM   2782 C CD    . GLU A 1 357 ? 233.249 202.820 213.062 1.00 74.61  ? 363 GLU J CD    1 
ATOM   2783 O OE1   . GLU A 1 357 ? 233.609 201.690 213.450 1.00 74.61  ? 363 GLU J OE1   1 
ATOM   2784 O OE2   . GLU A 1 357 ? 232.249 203.004 212.341 1.00 74.61  ? 363 GLU J OE2   1 
ATOM   2785 N N     . TYR A 1 358 ? 233.179 206.501 217.276 1.00 72.44  ? 364 TYR J N     1 
ATOM   2786 C CA    . TYR A 1 358 ? 232.412 207.329 218.200 1.00 72.44  ? 364 TYR J CA    1 
ATOM   2787 C C     . TYR A 1 358 ? 233.070 208.690 218.373 1.00 72.44  ? 364 TYR J C     1 
ATOM   2788 O O     . TYR A 1 358 ? 232.403 209.725 218.289 1.00 72.44  ? 364 TYR J O     1 
ATOM   2789 C CB    . TYR A 1 358 ? 232.264 206.614 219.544 1.00 72.44  ? 364 TYR J CB    1 
ATOM   2790 C CG    . TYR A 1 358 ? 231.602 207.441 220.620 1.00 72.44  ? 364 TYR J CG    1 
ATOM   2791 C CD1   . TYR A 1 358 ? 230.223 207.493 220.730 1.00 72.44  ? 364 TYR J CD1   1 
ATOM   2792 C CD2   . TYR A 1 358 ? 232.358 208.155 221.536 1.00 72.44  ? 364 TYR J CD2   1 
ATOM   2793 C CE1   . TYR A 1 358 ? 229.618 208.242 221.713 1.00 72.44  ? 364 TYR J CE1   1 
ATOM   2794 C CE2   . TYR A 1 358 ? 231.761 208.906 222.521 1.00 72.44  ? 364 TYR J CE2   1 
ATOM   2795 C CZ    . TYR A 1 358 ? 230.393 208.946 222.606 1.00 72.44  ? 364 TYR J CZ    1 
ATOM   2796 O OH    . TYR A 1 358 ? 229.799 209.696 223.591 1.00 72.44  ? 364 TYR J OH    1 
ATOM   2797 N N     . ASP A 1 359 ? 234.388 208.705 218.589 1.00 75.57  ? 365 ASP J N     1 
ATOM   2798 C CA    . ASP A 1 359 ? 235.110 209.969 218.699 1.00 75.57  ? 365 ASP J CA    1 
ATOM   2799 C C     . ASP A 1 359 ? 234.945 210.824 217.449 1.00 75.57  ? 365 ASP J C     1 
ATOM   2800 O O     . ASP A 1 359 ? 234.923 212.056 217.541 1.00 75.57  ? 365 ASP J O     1 
ATOM   2801 C CB    . ASP A 1 359 ? 236.593 209.710 218.960 1.00 75.57  ? 365 ASP J CB    1 
ATOM   2802 C CG    . ASP A 1 359 ? 236.861 209.209 220.364 1.00 75.57  ? 365 ASP J CG    1 
ATOM   2803 O OD1   . ASP A 1 359 ? 235.916 209.188 221.178 1.00 75.57  ? 365 ASP J OD1   1 
ATOM   2804 O OD2   . ASP A 1 359 ? 238.018 208.838 220.654 1.00 75.57  ? 365 ASP J OD2   1 
ATOM   2805 N N     . GLU A 1 360 ? 234.834 210.195 216.278 1.00 76.96  ? 366 GLU J N     1 
ATOM   2806 C CA    . GLU A 1 360 ? 234.661 210.963 215.048 1.00 76.96  ? 366 GLU J CA    1 
ATOM   2807 C C     . GLU A 1 360 ? 233.243 211.500 214.891 1.00 76.96  ? 366 GLU J C     1 
ATOM   2808 O O     . GLU A 1 360 ? 233.057 212.616 214.395 1.00 76.96  ? 366 GLU J O     1 
ATOM   2809 C CB    . GLU A 1 360 ? 235.022 210.117 213.829 1.00 76.96  ? 366 GLU J CB    1 
ATOM   2810 C CG    . GLU A 1 360 ? 236.410 209.527 213.846 1.00 76.96  ? 366 GLU J CG    1 
ATOM   2811 C CD    . GLU A 1 360 ? 236.830 209.017 212.484 1.00 76.96  ? 366 GLU J CD    1 
ATOM   2812 O OE1   . GLU A 1 360 ? 237.227 209.841 211.635 1.00 76.96  ? 366 GLU J OE1   1 
ATOM   2813 O OE2   . GLU A 1 360 ? 236.759 207.792 212.262 1.00 76.96  ? 366 GLU J OE2   1 
ATOM   2814 N N     . ALA A 1 361 ? 232.234 210.728 215.289 1.00 76.17  ? 367 ALA J N     1 
ATOM   2815 C CA    . ALA A 1 361 ? 230.856 211.052 214.933 1.00 76.17  ? 367 ALA J CA    1 
ATOM   2816 C C     . ALA A 1 361 ? 230.049 211.670 216.065 1.00 76.17  ? 367 ALA J C     1 
ATOM   2817 O O     . ALA A 1 361 ? 229.388 212.690 215.855 1.00 76.17  ? 367 ALA J O     1 
ATOM   2818 C CB    . ALA A 1 361 ? 230.135 209.796 214.436 1.00 76.17  ? 367 ALA J CB    1 
ATOM   2819 N N     . GLY A 1 362 ? 230.084 211.089 217.258 1.00 76.38  ? 368 GLY J N     1 
ATOM   2820 C CA    . GLY A 1 362 ? 229.186 211.483 218.315 1.00 76.38  ? 368 GLY J CA    1 
ATOM   2821 C C     . GLY A 1 362 ? 228.193 210.382 218.616 1.00 76.38  ? 368 GLY J C     1 
ATOM   2822 O O     . GLY A 1 362 ? 228.114 209.379 217.903 1.00 76.38  ? 368 GLY J O     1 
ATOM   2823 N N     . PRO A 1 363 ? 227.414 210.545 219.686 1.00 75.43  ? 369 PRO J N     1 
ATOM   2824 C CA    . PRO A 1 363 ? 226.464 209.488 220.072 1.00 75.43  ? 369 PRO J CA    1 
ATOM   2825 C C     . PRO A 1 363 ? 225.436 209.160 219.004 1.00 75.43  ? 369 PRO J C     1 
ATOM   2826 O O     . PRO A 1 363 ? 224.779 208.117 219.102 1.00 75.43  ? 369 PRO J O     1 
ATOM   2827 C CB    . PRO A 1 363 ? 225.793 210.058 221.328 1.00 75.43  ? 369 PRO J CB    1 
ATOM   2828 C CG    . PRO A 1 363 ? 226.750 211.078 221.847 1.00 75.43  ? 369 PRO J CG    1 
ATOM   2829 C CD    . PRO A 1 363 ? 227.432 211.659 220.648 1.00 75.43  ? 369 PRO J CD    1 
ATOM   2830 N N     . SER A 1 364 ? 225.273 210.006 217.990 1.00 77.03  ? 370 SER J N     1 
ATOM   2831 C CA    . SER A 1 364 ? 224.271 209.801 216.952 1.00 77.03  ? 370 SER J CA    1 
ATOM   2832 C C     . SER A 1 364 ? 224.688 208.776 215.908 1.00 77.03  ? 370 SER J C     1 
ATOM   2833 O O     . SER A 1 364 ? 224.007 208.647 214.887 1.00 77.03  ? 370 SER J O     1 
ATOM   2834 C CB    . SER A 1 364 ? 223.953 211.131 216.267 1.00 77.03  ? 370 SER J CB    1 
ATOM   2835 O OG    . SER A 1 364 ? 225.141 211.792 215.873 1.00 77.03  ? 370 SER J OG    1 
ATOM   2836 N N     . ILE A 1 365 ? 225.785 208.050 216.127 1.00 74.91  ? 371 ILE J N     1 
ATOM   2837 C CA    . ILE A 1 365 ? 226.226 207.072 215.140 1.00 74.91  ? 371 ILE J CA    1 
ATOM   2838 C C     . ILE A 1 365 ? 225.467 205.761 215.291 1.00 74.91  ? 371 ILE J C     1 
ATOM   2839 O O     . ILE A 1 365 ? 225.368 204.983 214.336 1.00 74.91  ? 371 ILE J O     1 
ATOM   2840 C CB    . ILE A 1 365 ? 227.747 206.858 215.247 1.00 74.91  ? 371 ILE J CB    1 
ATOM   2841 C CG1   . ILE A 1 365 ? 228.257 206.012 214.084 1.00 74.91  ? 371 ILE J CG1   1 
ATOM   2842 C CG2   . ILE A 1 365 ? 228.102 206.195 216.561 1.00 74.91  ? 371 ILE J CG2   1 
ATOM   2843 C CD1   . ILE A 1 365 ? 229.752 205.849 214.065 1.00 74.91  ? 371 ILE J CD1   1 
ATOM   2844 N N     . VAL A 1 366 ? 224.901 205.500 216.469 1.00 71.78  ? 372 VAL J N     1 
ATOM   2845 C CA    . VAL A 1 366 ? 224.452 204.149 216.785 1.00 71.78  ? 372 VAL J CA    1 
ATOM   2846 C C     . VAL A 1 366 ? 223.270 203.740 215.915 1.00 71.78  ? 372 VAL J C     1 
ATOM   2847 O O     . VAL A 1 366 ? 223.111 202.560 215.582 1.00 71.78  ? 372 VAL J O     1 
ATOM   2848 C CB    . VAL A 1 366 ? 224.129 204.026 218.284 1.00 71.78  ? 372 VAL J CB    1 
ATOM   2849 C CG1   . VAL A 1 366 ? 222.831 204.729 218.618 1.00 71.78  ? 372 VAL J CG1   1 
ATOM   2850 C CG2   . VAL A 1 366 ? 224.062 202.562 218.681 1.00 71.78  ? 372 VAL J CG2   1 
ATOM   2851 N N     . HIS A 1 367 ? 222.424 204.689 215.529 1.00 76.26  ? 373 HIS J N     1 
ATOM   2852 C CA    . HIS A 1 367 ? 221.266 204.360 214.711 1.00 76.26  ? 373 HIS J CA    1 
ATOM   2853 C C     . HIS A 1 367 ? 221.380 204.852 213.280 1.00 76.26  ? 373 HIS J C     1 
ATOM   2854 O O     . HIS A 1 367 ? 220.812 204.228 212.379 1.00 76.26  ? 373 HIS J O     1 
ATOM   2855 C CB    . HIS A 1 367 ? 219.987 204.921 215.343 1.00 76.26  ? 373 HIS J CB    1 
ATOM   2856 C CG    . HIS A 1 367 ? 220.008 206.403 215.530 1.00 76.26  ? 373 HIS J CG    1 
ATOM   2857 N ND1   . HIS A 1 367 ? 219.658 207.284 214.531 1.00 76.26  ? 373 HIS J ND1   1 
ATOM   2858 C CD2   . HIS A 1 367 ? 220.335 207.161 216.603 1.00 76.26  ? 373 HIS J CD2   1 
ATOM   2859 C CE1   . HIS A 1 367 ? 219.772 208.521 214.979 1.00 76.26  ? 373 HIS J CE1   1 
ATOM   2860 N NE2   . HIS A 1 367 ? 220.181 208.474 216.234 1.00 76.26  ? 373 HIS J NE2   1 
ATOM   2861 N N     . ARG A 1 368 ? 222.097 205.952 213.048 1.00 81.69  ? 374 ARG J N     1 
ATOM   2862 C CA    . ARG A 1 368 ? 222.257 206.452 211.688 1.00 81.69  ? 374 ARG J CA    1 
ATOM   2863 C C     . ARG A 1 368 ? 222.978 205.451 210.797 1.00 81.69  ? 374 ARG J C     1 
ATOM   2864 O O     . ARG A 1 368 ? 222.781 205.459 209.577 1.00 81.69  ? 374 ARG J O     1 
ATOM   2865 C CB    . ARG A 1 368 ? 223.025 207.774 211.691 1.00 81.69  ? 374 ARG J CB    1 
ATOM   2866 C CG    . ARG A 1 368 ? 222.222 208.986 212.119 1.00 81.69  ? 374 ARG J CG    1 
ATOM   2867 C CD    . ARG A 1 368 ? 223.120 210.212 212.167 1.00 81.69  ? 374 ARG J CD    1 
ATOM   2868 N NE    . ARG A 1 368 ? 224.384 209.920 212.840 1.00 81.69  ? 374 ARG J NE    1 
ATOM   2869 C CZ    . ARG A 1 368 ? 225.394 210.777 212.946 1.00 81.69  ? 374 ARG J CZ    1 
ATOM   2870 N NH1   . ARG A 1 368 ? 225.299 211.991 212.422 1.00 81.69  ? 374 ARG J NH1   1 
ATOM   2871 N NH2   . ARG A 1 368 ? 226.505 210.419 213.576 1.00 81.69  ? 374 ARG J NH2   1 
ATOM   2872 N N     . LYS A 1 369 ? 223.822 204.598 211.372 1.00 78.87  ? 375 LYS J N     1 
ATOM   2873 C CA    . LYS A 1 369 ? 224.641 203.723 210.546 1.00 78.87  ? 375 LYS J CA    1 
ATOM   2874 C C     . LYS A 1 369 ? 224.573 202.262 210.968 1.00 78.87  ? 375 LYS J C     1 
ATOM   2875 O O     . LYS A 1 369 ? 224.715 201.370 210.127 1.00 78.87  ? 375 LYS J O     1 
ATOM   2876 C CB    . LYS A 1 369 ? 226.094 204.201 210.563 1.00 78.87  ? 375 LYS J CB    1 
ATOM   2877 C CG    . LYS A 1 369 ? 226.461 205.127 209.413 1.00 78.87  ? 375 LYS J CG    1 
ATOM   2878 C CD    . LYS A 1 369 ? 225.929 206.533 209.626 1.00 78.87  ? 375 LYS J CD    1 
ATOM   2879 C CE    . LYS A 1 369 ? 226.619 207.208 210.793 1.00 78.87  ? 375 LYS J CE    1 
ATOM   2880 N NZ    . LYS A 1 369 ? 226.339 208.664 210.825 1.00 78.87  ? 375 LYS J NZ    1 
ATOM   2881 N N     . CYS A 1 370 ? 224.358 201.995 212.250 1.00 74.04  ? 376 CYS J N     1 
ATOM   2882 C CA    . CYS A 1 370 ? 224.497 200.629 212.743 1.00 74.04  ? 376 CYS J CA    1 
ATOM   2883 C C     . CYS A 1 370 ? 223.334 200.177 213.625 1.00 74.04  ? 376 CYS J C     1 
ATOM   2884 O O     . CYS A 1 370 ? 222.172 200.228 213.228 1.00 74.04  ? 376 CYS J O     1 
ATOM   2885 C CB    . CYS A 1 370 ? 225.812 200.495 213.507 1.00 74.04  ? 376 CYS J CB    1 
ATOM   2886 S SG    . CYS A 1 370 ? 227.285 200.781 212.497 1.00 74.04  ? 376 CYS J SG    1 
ATOM   2887 O OXT   . CYS A 1 370 ? 223.528 199.732 214.756 1.00 74.04  ? 376 CYS J OXT   1 
ATOM   2888 N N     . ALA B 2 1   ? 292.438 157.043 201.285 1.00 112.47 ? 4   ALA C N     1 
ATOM   2889 C CA    . ALA B 2 1   ? 293.233 157.423 202.447 1.00 112.47 ? 4   ALA C CA    1 
ATOM   2890 C C     . ALA B 2 1   ? 292.332 157.812 203.612 1.00 112.47 ? 4   ALA C C     1 
ATOM   2891 O O     . ALA B 2 1   ? 292.095 157.015 204.519 1.00 112.47 ? 4   ALA C O     1 
ATOM   2892 C CB    . ALA B 2 1   ? 294.171 158.565 202.097 1.00 112.47 ? 4   ALA C CB    1 
ATOM   2893 N N     . GLN B 2 2   ? 291.829 159.044 203.578 1.00 113.08 ? 5   GLN C N     1 
ATOM   2894 C CA    . GLN B 2 2   ? 290.899 159.529 204.589 1.00 113.08 ? 5   GLN C CA    1 
ATOM   2895 C C     . GLN B 2 2   ? 289.523 158.887 204.481 1.00 113.08 ? 5   GLN C C     1 
ATOM   2896 O O     . GLN B 2 2   ? 288.649 159.190 205.300 1.00 113.08 ? 5   GLN C O     1 
ATOM   2897 C CB    . GLN B 2 2   ? 290.765 161.052 204.491 1.00 113.08 ? 5   GLN C CB    1 
ATOM   2898 C CG    . GLN B 2 2   ? 289.938 161.546 203.308 1.00 113.08 ? 5   GLN C CG    1 
ATOM   2899 C CD    . GLN B 2 2   ? 290.710 161.571 201.996 1.00 113.08 ? 5   GLN C CD    1 
ATOM   2900 O OE1   . GLN B 2 2   ? 291.597 160.752 201.762 1.00 113.08 ? 5   GLN C OE1   1 
ATOM   2901 N NE2   . GLN B 2 2   ? 290.367 162.519 201.130 1.00 113.08 ? 5   GLN C NE2   1 
ATOM   2902 N N     . MET B 2 3   ? 289.315 158.013 203.497 1.00 109.44 ? 6   MET C N     1 
ATOM   2903 C CA    . MET B 2 3   ? 288.042 157.346 203.281 1.00 109.44 ? 6   MET C CA    1 
ATOM   2904 C C     . MET B 2 3   ? 288.139 155.828 203.350 1.00 109.44 ? 6   MET C C     1 
ATOM   2905 O O     . MET B 2 3   ? 287.104 155.165 203.467 1.00 109.44 ? 6   MET C O     1 
ATOM   2906 C CB    . MET B 2 3   ? 287.459 157.779 201.921 1.00 109.44 ? 6   MET C CB    1 
ATOM   2907 C CG    . MET B 2 3   ? 286.075 157.257 201.543 1.00 109.44 ? 6   MET C CG    1 
ATOM   2908 S SD    . MET B 2 3   ? 286.120 155.694 200.645 1.00 109.44 ? 6   MET C SD    1 
ATOM   2909 C CE    . MET B 2 3   ? 286.815 156.223 199.082 1.00 109.44 ? 6   MET C CE    1 
ATOM   2910 N N     . ALA B 2 4   ? 289.343 155.263 203.335 1.00 109.30 ? 7   ALA C N     1 
ATOM   2911 C CA    . ALA B 2 4   ? 289.514 153.818 203.279 1.00 109.30 ? 7   ALA C CA    1 
ATOM   2912 C C     . ALA B 2 4   ? 289.186 153.114 204.589 1.00 109.30 ? 7   ALA C C     1 
ATOM   2913 O O     . ALA B 2 4   ? 289.237 151.879 204.632 1.00 109.30 ? 7   ALA C O     1 
ATOM   2914 C CB    . ALA B 2 4   ? 290.948 153.477 202.862 1.00 109.30 ? 7   ALA C CB    1 
ATOM   2915 N N     . ASP B 2 5   ? 288.847 153.848 205.648 1.00 105.84 ? 8   ASP C N     1 
ATOM   2916 C CA    . ASP B 2 5   ? 288.587 153.249 206.949 1.00 105.84 ? 8   ASP C CA    1 
ATOM   2917 C C     . ASP B 2 5   ? 287.109 152.963 207.189 1.00 105.84 ? 8   ASP C C     1 
ATOM   2918 O O     . ASP B 2 5   ? 286.712 152.742 208.337 1.00 105.84 ? 8   ASP C O     1 
ATOM   2919 C CB    . ASP B 2 5   ? 289.134 154.144 208.062 1.00 105.84 ? 8   ASP C CB    1 
ATOM   2920 C CG    . ASP B 2 5   ? 288.298 155.386 208.274 1.00 105.84 ? 8   ASP C CG    1 
ATOM   2921 O OD1   . ASP B 2 5   ? 287.391 155.352 209.131 1.00 105.84 ? 8   ASP C OD1   1 
ATOM   2922 O OD2   . ASP B 2 5   ? 288.550 156.396 207.584 1.00 105.84 ? 8   ASP C OD2   1 
ATOM   2923 N N     . PHE B 2 6   ? 286.290 152.960 206.139 1.00 99.47  ? 9   PHE C N     1 
ATOM   2924 C CA    . PHE B 2 6   ? 284.891 152.567 206.242 1.00 99.47  ? 9   PHE C CA    1 
ATOM   2925 C C     . PHE B 2 6   ? 284.658 151.112 205.862 1.00 99.47  ? 9   PHE C C     1 
ATOM   2926 O O     . PHE B 2 6   ? 283.520 150.642 205.938 1.00 99.47  ? 9   PHE C O     1 
ATOM   2927 C CB    . PHE B 2 6   ? 284.012 153.475 205.373 1.00 99.47  ? 9   PHE C CB    1 
ATOM   2928 C CG    . PHE B 2 6   ? 283.953 154.900 205.847 1.00 99.47  ? 9   PHE C CG    1 
ATOM   2929 C CD1   . PHE B 2 6   ? 282.882 155.348 206.593 1.00 99.47  ? 9   PHE C CD1   1 
ATOM   2930 C CD2   . PHE B 2 6   ? 284.963 155.793 205.540 1.00 99.47  ? 9   PHE C CD2   1 
ATOM   2931 C CE1   . PHE B 2 6   ? 282.821 156.656 207.029 1.00 99.47  ? 9   PHE C CE1   1 
ATOM   2932 C CE2   . PHE B 2 6   ? 284.908 157.103 205.974 1.00 99.47  ? 9   PHE C CE2   1 
ATOM   2933 C CZ    . PHE B 2 6   ? 283.836 157.534 206.719 1.00 99.47  ? 9   PHE C CZ    1 
ATOM   2934 N N     . GLY B 2 7   ? 285.699 150.395 205.452 1.00 99.04  ? 10  GLY C N     1 
ATOM   2935 C CA    . GLY B 2 7   ? 285.564 148.963 205.226 1.00 99.04  ? 10  GLY C CA    1 
ATOM   2936 C C     . GLY B 2 7   ? 284.761 148.653 203.978 1.00 99.04  ? 10  GLY C C     1 
ATOM   2937 O O     . GLY B 2 7   ? 285.050 149.149 202.883 1.00 99.04  ? 10  GLY C O     1 
ATOM   2938 N N     . ALA B 2 8   ? 283.736 147.815 204.140 1.00 97.45  ? 11  ALA C N     1 
ATOM   2939 C CA    . ALA B 2 8   ? 282.890 147.405 203.029 1.00 97.45  ? 11  ALA C CA    1 
ATOM   2940 C C     . ALA B 2 8   ? 281.828 148.435 202.673 1.00 97.45  ? 11  ALA C C     1 
ATOM   2941 O O     . ALA B 2 8   ? 281.018 148.179 201.777 1.00 97.45  ? 11  ALA C O     1 
ATOM   2942 C CB    . ALA B 2 8   ? 282.218 146.068 203.347 1.00 97.45  ? 11  ALA C CB    1 
ATOM   2943 N N     . ALA B 2 9   ? 281.802 149.579 203.351 1.00 95.99  ? 12  ALA C N     1 
ATOM   2944 C CA    . ALA B 2 9   ? 280.884 150.657 203.018 1.00 95.99  ? 12  ALA C CA    1 
ATOM   2945 C C     . ALA B 2 9   ? 281.528 151.741 202.170 1.00 95.99  ? 12  ALA C C     1 
ATOM   2946 O O     . ALA B 2 9   ? 280.821 152.644 201.708 1.00 95.99  ? 12  ALA C O     1 
ATOM   2947 C CB    . ALA B 2 9   ? 280.313 151.285 204.294 1.00 95.99  ? 12  ALA C CB    1 
ATOM   2948 N N     . ALA B 2 10  ? 282.845 151.676 201.963 1.00 97.00  ? 13  ALA C N     1 
ATOM   2949 C CA    . ALA B 2 10  ? 283.533 152.706 201.195 1.00 97.00  ? 13  ALA C CA    1 
ATOM   2950 C C     . ALA B 2 10  ? 282.957 152.829 199.791 1.00 97.00  ? 13  ALA C C     1 
ATOM   2951 O O     . ALA B 2 10  ? 282.758 153.941 199.290 1.00 97.00  ? 13  ALA C O     1 
ATOM   2952 C CB    . ALA B 2 10  ? 285.027 152.398 201.137 1.00 97.00  ? 13  ALA C CB    1 
ATOM   2953 N N     . GLN B 2 11  ? 282.670 151.698 199.144 1.00 96.36  ? 14  GLN C N     1 
ATOM   2954 C CA    . GLN B 2 11  ? 282.114 151.739 197.796 1.00 96.36  ? 14  GLN C CA    1 
ATOM   2955 C C     . GLN B 2 11  ? 280.715 152.342 197.777 1.00 96.36  ? 14  GLN C C     1 
ATOM   2956 O O     . GLN B 2 11  ? 280.258 152.809 196.728 1.00 96.36  ? 14  GLN C O     1 
ATOM   2957 C CB    . GLN B 2 11  ? 282.093 150.335 197.194 1.00 96.36  ? 14  GLN C CB    1 
ATOM   2958 C CG    . GLN B 2 11  ? 281.481 149.284 198.103 1.00 96.36  ? 14  GLN C CG    1 
ATOM   2959 C CD    . GLN B 2 11  ? 281.617 147.884 197.544 1.00 96.36  ? 14  GLN C CD    1 
ATOM   2960 O OE1   . GLN B 2 11  ? 282.079 146.971 198.228 1.00 96.36  ? 14  GLN C OE1   1 
ATOM   2961 N NE2   . GLN B 2 11  ? 281.216 147.707 196.291 1.00 96.36  ? 14  GLN C NE2   1 
ATOM   2962 N N     . TYR B 2 12  ? 280.022 152.340 198.913 1.00 94.19  ? 15  TYR C N     1 
ATOM   2963 C CA    . TYR B 2 12  ? 278.667 152.867 198.971 1.00 94.19  ? 15  TYR C CA    1 
ATOM   2964 C C     . TYR B 2 12  ? 278.592 154.271 199.552 1.00 94.19  ? 15  TYR C C     1 
ATOM   2965 O O     . TYR B 2 12  ? 277.516 154.878 199.524 1.00 94.19  ? 15  TYR C O     1 
ATOM   2966 C CB    . TYR B 2 12  ? 277.772 151.929 199.782 1.00 94.19  ? 15  TYR C CB    1 
ATOM   2967 C CG    . TYR B 2 12  ? 277.782 150.502 199.285 1.00 94.19  ? 15  TYR C CG    1 
ATOM   2968 C CD1   . TYR B 2 12  ? 277.210 150.168 198.066 1.00 94.19  ? 15  TYR C CD1   1 
ATOM   2969 C CD2   . TYR B 2 12  ? 278.358 149.489 200.035 1.00 94.19  ? 15  TYR C CD2   1 
ATOM   2970 C CE1   . TYR B 2 12  ? 277.216 148.867 197.607 1.00 94.19  ? 15  TYR C CE1   1 
ATOM   2971 C CE2   . TYR B 2 12  ? 278.367 148.185 199.585 1.00 94.19  ? 15  TYR C CE2   1 
ATOM   2972 C CZ    . TYR B 2 12  ? 277.795 147.880 198.371 1.00 94.19  ? 15  TYR C CZ    1 
ATOM   2973 O OH    . TYR B 2 12  ? 277.803 146.580 197.921 1.00 94.19  ? 15  TYR C OH    1 
ATOM   2974 N N     . LEU B 2 13  ? 279.693 154.797 200.089 1.00 92.21  ? 16  LEU C N     1 
ATOM   2975 C CA    . LEU B 2 13  ? 279.706 156.176 200.572 1.00 92.21  ? 16  LEU C CA    1 
ATOM   2976 C C     . LEU B 2 13  ? 280.357 157.122 199.567 1.00 92.21  ? 16  LEU C C     1 
ATOM   2977 O O     . LEU B 2 13  ? 279.769 158.139 199.191 1.00 92.21  ? 16  LEU C O     1 
ATOM   2978 C CB    . LEU B 2 13  ? 280.416 156.273 201.929 1.00 92.21  ? 16  LEU C CB    1 
ATOM   2979 C CG    . LEU B 2 13  ? 279.606 156.003 203.201 1.00 92.21  ? 16  LEU C CG    1 
ATOM   2980 C CD1   . LEU B 2 13  ? 278.524 157.049 203.353 1.00 92.21  ? 16  LEU C CD1   1 
ATOM   2981 C CD2   . LEU B 2 13  ? 279.003 154.619 203.225 1.00 92.21  ? 16  LEU C CD2   1 
ATOM   2982 N N     . ARG B 2 14  ? 281.574 156.806 199.133 1.00 97.50  ? 17  ARG C N     1 
ATOM   2983 C CA    . ARG B 2 14  ? 282.312 157.656 198.209 1.00 97.50  ? 17  ARG C CA    1 
ATOM   2984 C C     . ARG B 2 14  ? 282.999 156.792 197.168 1.00 97.50  ? 17  ARG C C     1 
ATOM   2985 O O     . ARG B 2 14  ? 283.593 155.765 197.506 1.00 97.50  ? 17  ARG C O     1 
ATOM   2986 C CB    . ARG B 2 14  ? 283.361 158.503 198.936 1.00 97.50  ? 17  ARG C CB    1 
ATOM   2987 C CG    . ARG B 2 14  ? 282.816 159.368 200.043 1.00 97.50  ? 17  ARG C CG    1 
ATOM   2988 C CD    . ARG B 2 14  ? 283.695 160.575 200.239 1.00 97.50  ? 17  ARG C CD    1 
ATOM   2989 N NE    . ARG B 2 14  ? 284.161 161.094 198.960 1.00 97.50  ? 17  ARG C NE    1 
ATOM   2990 C CZ    . ARG B 2 14  ? 284.717 162.288 198.803 1.00 97.50  ? 17  ARG C CZ    1 
ATOM   2991 N NH1   . ARG B 2 14  ? 284.877 163.086 199.849 1.00 97.50  ? 17  ARG C NH1   1 
ATOM   2992 N NH2   . ARG B 2 14  ? 285.113 162.684 197.603 1.00 97.50  ? 17  ARG C NH2   1 
ATOM   2993 N N     . LYS B 2 15  ? 282.927 157.211 195.911 1.00 101.42 ? 18  LYS C N     1 
ATOM   2994 C CA    . LYS B 2 15  ? 283.687 156.531 194.879 1.00 101.42 ? 18  LYS C CA    1 
ATOM   2995 C C     . LYS B 2 15  ? 285.168 156.847 195.035 1.00 101.42 ? 18  LYS C C     1 
ATOM   2996 O O     . LYS B 2 15  ? 285.551 157.923 195.501 1.00 101.42 ? 18  LYS C O     1 
ATOM   2997 C CB    . LYS B 2 15  ? 283.197 156.938 193.491 1.00 101.42 ? 18  LYS C CB    1 
ATOM   2998 C CG    . LYS B 2 15  ? 281.867 156.318 193.108 1.00 101.42 ? 18  LYS C CG    1 
ATOM   2999 C CD    . LYS B 2 15  ? 281.860 154.829 193.397 1.00 101.42 ? 18  LYS C CD    1 
ATOM   3000 C CE    . LYS B 2 15  ? 280.471 154.241 193.241 1.00 101.42 ? 18  LYS C CE    1 
ATOM   3001 N NZ    . LYS B 2 15  ? 280.440 152.804 193.618 1.00 101.42 ? 18  LYS C NZ    1 
ATOM   3002 N N     . SER B 2 16  ? 286.003 155.883 194.658 1.00 108.73 ? 19  SER C N     1 
ATOM   3003 C CA    . SER B 2 16  ? 287.444 156.043 194.772 1.00 108.73 ? 19  SER C CA    1 
ATOM   3004 C C     . SER B 2 16  ? 287.915 157.256 193.977 1.00 108.73 ? 19  SER C C     1 
ATOM   3005 O O     . SER B 2 16  ? 287.216 157.772 193.101 1.00 108.73 ? 19  SER C O     1 
ATOM   3006 C CB    . SER B 2 16  ? 288.160 154.787 194.278 1.00 108.73 ? 19  SER C CB    1 
ATOM   3007 O OG    . SER B 2 16  ? 287.601 154.334 193.058 1.00 108.73 ? 19  SER C OG    1 
ATOM   3008 N N     . GLU B 2 17  ? 289.124 157.718 194.300 1.00 111.19 ? 20  GLU C N     1 
ATOM   3009 C CA    . GLU B 2 17  ? 289.691 158.842 193.566 1.00 111.19 ? 20  GLU C CA    1 
ATOM   3010 C C     . GLU B 2 17  ? 289.844 158.515 192.088 1.00 111.19 ? 20  GLU C C     1 
ATOM   3011 O O     . GLU B 2 17  ? 289.693 159.397 191.238 1.00 111.19 ? 20  GLU C O     1 
ATOM   3012 C CB    . GLU B 2 17  ? 291.038 159.241 194.168 1.00 111.19 ? 20  GLU C CB    1 
ATOM   3013 C CG    . GLU B 2 17  ? 291.612 160.525 193.599 1.00 111.19 ? 20  GLU C CG    1 
ATOM   3014 C CD    . GLU B 2 17  ? 292.769 161.057 194.419 1.00 111.19 ? 20  GLU C CD    1 
ATOM   3015 O OE1   . GLU B 2 17  ? 293.148 160.402 195.411 1.00 111.19 ? 20  GLU C OE1   1 
ATOM   3016 O OE2   . GLU B 2 17  ? 293.300 162.132 194.071 1.00 111.19 ? 20  GLU C OE2   1 
ATOM   3017 N N     . LYS B 2 18  ? 290.114 157.250 191.763 1.00 112.03 ? 21  LYS C N     1 
ATOM   3018 C CA    . LYS B 2 18  ? 290.237 156.844 190.368 1.00 112.03 ? 21  LYS C CA    1 
ATOM   3019 C C     . LYS B 2 18  ? 288.930 157.057 189.613 1.00 112.03 ? 21  LYS C C     1 
ATOM   3020 O O     . LYS B 2 18  ? 288.891 157.779 188.609 1.00 112.03 ? 21  LYS C O     1 
ATOM   3021 C CB    . LYS B 2 18  ? 290.672 155.380 190.288 1.00 112.03 ? 21  LYS C CB    1 
ATOM   3022 C CG    . LYS B 2 18  ? 290.583 154.784 188.893 1.00 112.03 ? 21  LYS C CG    1 
ATOM   3023 C CD    . LYS B 2 18  ? 291.580 155.433 187.945 1.00 112.03 ? 21  LYS C CD    1 
ATOM   3024 C CE    . LYS B 2 18  ? 291.438 154.885 186.536 1.00 112.03 ? 21  LYS C CE    1 
ATOM   3025 N NZ    . LYS B 2 18  ? 290.147 155.287 185.913 1.00 112.03 ? 21  LYS C NZ    1 
ATOM   3026 N N     . GLU B 2 19  ? 287.849 156.420 190.074 1.00 112.28 ? 22  GLU C N     1 
ATOM   3027 C CA    . GLU B 2 19  ? 286.586 156.486 189.346 1.00 112.28 ? 22  GLU C CA    1 
ATOM   3028 C C     . GLU B 2 19  ? 286.012 157.894 189.333 1.00 112.28 ? 22  GLU C C     1 
ATOM   3029 O O     . GLU B 2 19  ? 285.443 158.318 188.321 1.00 112.28 ? 22  GLU C O     1 
ATOM   3030 C CB    . GLU B 2 19  ? 285.577 155.506 189.943 1.00 112.28 ? 22  GLU C CB    1 
ATOM   3031 C CG    . GLU B 2 19  ? 285.610 154.131 189.298 1.00 112.28 ? 22  GLU C CG    1 
ATOM   3032 C CD    . GLU B 2 19  ? 284.862 153.085 190.099 1.00 112.28 ? 22  GLU C CD    1 
ATOM   3033 O OE1   . GLU B 2 19  ? 284.651 153.297 191.311 1.00 112.28 ? 22  GLU C OE1   1 
ATOM   3034 O OE2   . GLU B 2 19  ? 284.485 152.048 189.514 1.00 112.28 ? 22  GLU C OE2   1 
ATOM   3035 N N     . ARG B 2 20  ? 286.165 158.638 190.428 1.00 108.59 ? 23  ARG C N     1 
ATOM   3036 C CA    . ARG B 2 20  ? 285.732 160.030 190.425 1.00 108.59 ? 23  ARG C CA    1 
ATOM   3037 C C     . ARG B 2 20  ? 286.526 160.841 189.410 1.00 108.59 ? 23  ARG C C     1 
ATOM   3038 O O     . ARG B 2 20  ? 285.947 161.492 188.534 1.00 108.59 ? 23  ARG C O     1 
ATOM   3039 C CB    . ARG B 2 20  ? 285.870 160.634 191.821 1.00 108.59 ? 23  ARG C CB    1 
ATOM   3040 C CG    . ARG B 2 20  ? 284.867 160.110 192.827 1.00 108.59 ? 23  ARG C CG    1 
ATOM   3041 C CD    . ARG B 2 20  ? 285.002 160.826 194.159 1.00 108.59 ? 23  ARG C CD    1 
ATOM   3042 N NE    . ARG B 2 20  ? 286.200 160.419 194.884 1.00 108.59 ? 23  ARG C NE    1 
ATOM   3043 C CZ    . ARG B 2 20  ? 287.090 161.267 195.385 1.00 108.59 ? 23  ARG C CZ    1 
ATOM   3044 N NH1   . ARG B 2 20  ? 286.919 162.572 195.237 1.00 108.59 ? 23  ARG C NH1   1 
ATOM   3045 N NH2   . ARG B 2 20  ? 288.151 160.810 196.034 1.00 108.59 ? 23  ARG C NH2   1 
ATOM   3046 N N     . LEU B 2 21  ? 287.857 160.795 189.500 1.00 110.91 ? 24  LEU C N     1 
ATOM   3047 C CA    . LEU B 2 21  ? 288.693 161.589 188.610 1.00 110.91 ? 24  LEU C CA    1 
ATOM   3048 C C     . LEU B 2 21  ? 288.472 161.228 187.146 1.00 110.91 ? 24  LEU C C     1 
ATOM   3049 O O     . LEU B 2 21  ? 288.609 162.089 186.270 1.00 110.91 ? 24  LEU C O     1 
ATOM   3050 C CB    . LEU B 2 21  ? 290.162 161.414 188.993 1.00 110.91 ? 24  LEU C CB    1 
ATOM   3051 C CG    . LEU B 2 21  ? 291.226 161.812 187.973 1.00 110.91 ? 24  LEU C CG    1 
ATOM   3052 C CD1   . LEU B 2 21  ? 291.317 163.324 187.870 1.00 110.91 ? 24  LEU C CD1   1 
ATOM   3053 C CD2   . LEU B 2 21  ? 292.570 161.210 188.344 1.00 110.91 ? 24  LEU C CD2   1 
ATOM   3054 N N     . GLU B 2 22  ? 288.116 159.977 186.854 1.00 113.13 ? 25  GLU C N     1 
ATOM   3055 C CA    . GLU B 2 22  ? 287.819 159.625 185.472 1.00 113.13 ? 25  GLU C CA    1 
ATOM   3056 C C     . GLU B 2 22  ? 286.371 159.902 185.095 1.00 113.13 ? 25  GLU C C     1 
ATOM   3057 O O     . GLU B 2 22  ? 286.038 159.852 183.907 1.00 113.13 ? 25  GLU C O     1 
ATOM   3058 C CB    . GLU B 2 22  ? 288.158 158.155 185.200 1.00 113.13 ? 25  GLU C CB    1 
ATOM   3059 C CG    . GLU B 2 22  ? 287.323 157.147 185.960 1.00 113.13 ? 25  GLU C CG    1 
ATOM   3060 C CD    . GLU B 2 22  ? 286.056 156.763 185.225 1.00 113.13 ? 25  GLU C CD    1 
ATOM   3061 O OE1   . GLU B 2 22  ? 285.997 156.965 183.995 1.00 113.13 ? 25  GLU C OE1   1 
ATOM   3062 O OE2   . GLU B 2 22  ? 285.118 156.261 185.878 1.00 113.13 ? 25  GLU C OE2   1 
ATOM   3063 N N     . ALA B 2 23  ? 285.505 160.188 186.067 1.00 109.28 ? 26  ALA C N     1 
ATOM   3064 C CA    . ALA B 2 23  ? 284.144 160.607 185.769 1.00 109.28 ? 26  ALA C CA    1 
ATOM   3065 C C     . ALA B 2 23  ? 283.986 162.118 185.699 1.00 109.28 ? 26  ALA C C     1 
ATOM   3066 O O     . ALA B 2 23  ? 282.984 162.594 185.156 1.00 109.28 ? 26  ALA C O     1 
ATOM   3067 C CB    . ALA B 2 23  ? 283.172 160.049 186.814 1.00 109.28 ? 26  ALA C CB    1 
ATOM   3068 N N     . GLN B 2 24  ? 284.940 162.878 186.235 1.00 109.12 ? 27  GLN C N     1 
ATOM   3069 C CA    . GLN B 2 24  ? 284.929 164.333 186.145 1.00 109.12 ? 27  GLN C CA    1 
ATOM   3070 C C     . GLN B 2 24  ? 285.593 164.852 184.875 1.00 109.12 ? 27  GLN C C     1 
ATOM   3071 O O     . GLN B 2 24  ? 285.798 166.064 184.756 1.00 109.12 ? 27  GLN C O     1 
ATOM   3072 C CB    . GLN B 2 24  ? 285.624 164.946 187.365 1.00 109.12 ? 27  GLN C CB    1 
ATOM   3073 C CG    . GLN B 2 24  ? 285.115 164.448 188.708 1.00 109.12 ? 27  GLN C CG    1 
ATOM   3074 C CD    . GLN B 2 24  ? 283.834 165.125 189.140 1.00 109.12 ? 27  GLN C CD    1 
ATOM   3075 O OE1   . GLN B 2 24  ? 283.747 166.351 189.170 1.00 109.12 ? 27  GLN C OE1   1 
ATOM   3076 N NE2   . GLN B 2 24  ? 282.829 164.327 189.482 1.00 109.12 ? 27  GLN C NE2   1 
ATOM   3077 N N     . THR B 2 25  ? 285.937 163.974 183.934 1.00 115.31 ? 28  THR C N     1 
ATOM   3078 C CA    . THR B 2 25  ? 286.648 164.357 182.716 1.00 115.31 ? 28  THR C CA    1 
ATOM   3079 C C     . THR B 2 25  ? 285.977 163.757 181.489 1.00 115.31 ? 28  THR C C     1 
ATOM   3080 O O     . THR B 2 25  ? 286.640 163.223 180.595 1.00 115.31 ? 28  THR C O     1 
ATOM   3081 C CB    . THR B 2 25  ? 288.120 163.938 182.768 1.00 115.31 ? 28  THR C CB    1 
ATOM   3082 O OG1   . THR B 2 25  ? 288.222 162.521 182.582 1.00 115.31 ? 28  THR C OG1   1 
ATOM   3083 C CG2   . THR B 2 25  ? 288.767 164.337 184.088 1.00 115.31 ? 28  THR C CG2   1 
ATOM   3084 N N     . ARG B 2 26  ? 284.660 163.829 181.430 1.00 117.42 ? 29  ARG C N     1 
ATOM   3085 C CA    . ARG B 2 26  ? 283.993 163.384 180.217 1.00 117.42 ? 29  ARG C CA    1 
ATOM   3086 C C     . ARG B 2 26  ? 283.860 164.550 179.242 1.00 117.42 ? 29  ARG C C     1 
ATOM   3087 O O     . ARG B 2 26  ? 283.619 165.683 179.663 1.00 117.42 ? 29  ARG C O     1 
ATOM   3088 C CB    . ARG B 2 26  ? 282.610 162.824 180.534 1.00 117.42 ? 29  ARG C CB    1 
ATOM   3089 C CG    . ARG B 2 26  ? 282.597 161.572 181.393 1.00 117.42 ? 29  ARG C CG    1 
ATOM   3090 C CD    . ARG B 2 26  ? 283.216 160.384 180.677 1.00 117.42 ? 29  ARG C CD    1 
ATOM   3091 N NE    . ARG B 2 26  ? 284.650 160.276 180.920 1.00 117.42 ? 29  ARG C NE    1 
ATOM   3092 C CZ    . ARG B 2 26  ? 285.465 159.481 180.236 1.00 117.42 ? 29  ARG C CZ    1 
ATOM   3093 N NH1   . ARG B 2 26  ? 284.986 158.722 179.260 1.00 117.42 ? 29  ARG C NH1   1 
ATOM   3094 N NH2   . ARG B 2 26  ? 286.757 159.443 180.528 1.00 117.42 ? 29  ARG C NH2   1 
ATOM   3095 N N     . PRO B 2 27  ? 284.030 164.311 177.945 1.00 120.80 ? 30  PRO C N     1 
ATOM   3096 C CA    . PRO B 2 27  ? 283.819 165.378 176.958 1.00 120.80 ? 30  PRO C CA    1 
ATOM   3097 C C     . PRO B 2 27  ? 282.338 165.575 176.672 1.00 120.80 ? 30  PRO C C     1 
ATOM   3098 O O     . PRO B 2 27  ? 281.719 164.790 175.946 1.00 120.80 ? 30  PRO C O     1 
ATOM   3099 C CB    . PRO B 2 27  ? 284.580 164.864 175.728 1.00 120.80 ? 30  PRO C CB    1 
ATOM   3100 C CG    . PRO B 2 27  ? 284.526 163.379 175.853 1.00 120.80 ? 30  PRO C CG    1 
ATOM   3101 C CD    . PRO B 2 27  ? 284.466 163.049 177.322 1.00 120.80 ? 30  PRO C CD    1 
ATOM   3102 N N     . PHE B 2 28  ? 281.774 166.653 177.214 1.00 121.26 ? 31  PHE C N     1 
ATOM   3103 C CA    . PHE B 2 28  ? 280.373 166.993 177.018 1.00 121.26 ? 31  PHE C CA    1 
ATOM   3104 C C     . PHE B 2 28  ? 280.277 168.443 176.574 1.00 121.26 ? 31  PHE C C     1 
ATOM   3105 O O     . PHE B 2 28  ? 280.891 169.332 177.169 1.00 121.26 ? 31  PHE C O     1 
ATOM   3106 C CB    . PHE B 2 28  ? 279.536 166.784 178.294 1.00 121.26 ? 31  PHE C CB    1 
ATOM   3107 C CG    . PHE B 2 28  ? 279.432 165.347 178.733 1.00 121.26 ? 31  PHE C CG    1 
ATOM   3108 C CD1   . PHE B 2 28  ? 279.478 164.318 177.809 1.00 121.26 ? 31  PHE C CD1   1 
ATOM   3109 C CD2   . PHE B 2 28  ? 279.281 165.028 180.072 1.00 121.26 ? 31  PHE C CD2   1 
ATOM   3110 C CE1   . PHE B 2 28  ? 279.384 163.001 178.210 1.00 121.26 ? 31  PHE C CE1   1 
ATOM   3111 C CE2   . PHE B 2 28  ? 279.184 163.711 180.479 1.00 121.26 ? 31  PHE C CE2   1 
ATOM   3112 C CZ    . PHE B 2 28  ? 279.235 162.697 179.547 1.00 121.26 ? 31  PHE C CZ    1 
ATOM   3113 N N     . ASP B 2 29  ? 279.486 168.674 175.533 1.00 120.62 ? 32  ASP C N     1 
ATOM   3114 C CA    . ASP B 2 29  ? 279.392 169.986 174.915 1.00 120.62 ? 32  ASP C CA    1 
ATOM   3115 C C     . ASP B 2 29  ? 278.415 170.871 175.681 1.00 120.62 ? 32  ASP C C     1 
ATOM   3116 O O     . ASP B 2 29  ? 277.456 170.392 176.291 1.00 120.62 ? 32  ASP C O     1 
ATOM   3117 C CB    . ASP B 2 29  ? 278.957 169.856 173.455 1.00 120.62 ? 32  ASP C CB    1 
ATOM   3118 C CG    . ASP B 2 29  ? 279.091 171.152 172.684 1.00 120.62 ? 32  ASP C CG    1 
ATOM   3119 O OD1   . ASP B 2 29  ? 279.506 172.168 173.279 1.00 120.62 ? 32  ASP C OD1   1 
ATOM   3120 O OD2   . ASP B 2 29  ? 278.782 171.155 171.475 1.00 120.62 ? 32  ASP C OD2   1 
ATOM   3121 N N     . ILE B 2 30  ? 278.670 172.179 175.634 1.00 119.16 ? 33  ILE C N     1 
ATOM   3122 C CA    . ILE B 2 30  ? 277.905 173.122 176.441 1.00 119.16 ? 33  ILE C CA    1 
ATOM   3123 C C     . ILE B 2 30  ? 276.517 173.351 175.859 1.00 119.16 ? 33  ILE C C     1 
ATOM   3124 O O     . ILE B 2 30  ? 275.508 173.183 176.551 1.00 119.16 ? 33  ILE C O     1 
ATOM   3125 C CB    . ILE B 2 30  ? 278.680 174.445 176.580 1.00 119.16 ? 33  ILE C CB    1 
ATOM   3126 C CG1   . ILE B 2 30  ? 279.931 174.251 177.440 1.00 119.16 ? 33  ILE C CG1   1 
ATOM   3127 C CG2   . ILE B 2 30  ? 277.784 175.527 177.163 1.00 119.16 ? 33  ILE C CG2   1 
ATOM   3128 C CD1   . ILE B 2 30  ? 280.715 175.527 177.672 1.00 119.16 ? 33  ILE C CD1   1 
ATOM   3129 N N     . ARG B 2 31  ? 276.437 173.728 174.585 1.00 120.22 ? 34  ARG C N     1 
ATOM   3130 C CA    . ARG B 2 31  ? 275.189 174.183 173.989 1.00 120.22 ? 34  ARG C CA    1 
ATOM   3131 C C     . ARG B 2 31  ? 274.437 173.081 173.254 1.00 120.22 ? 34  ARG C C     1 
ATOM   3132 O O     . ARG B 2 31  ? 273.434 173.368 172.593 1.00 120.22 ? 34  ARG C O     1 
ATOM   3133 C CB    . ARG B 2 31  ? 275.459 175.347 173.035 1.00 120.22 ? 34  ARG C CB    1 
ATOM   3134 C CG    . ARG B 2 31  ? 275.942 176.613 173.717 1.00 120.22 ? 34  ARG C CG    1 
ATOM   3135 C CD    . ARG B 2 31  ? 276.845 177.415 172.792 1.00 120.22 ? 34  ARG C CD    1 
ATOM   3136 N NE    . ARG B 2 31  ? 277.946 176.606 172.275 1.00 120.22 ? 34  ARG C NE    1 
ATOM   3137 C CZ    . ARG B 2 31  ? 279.052 176.327 172.956 1.00 120.22 ? 34  ARG C CZ    1 
ATOM   3138 N NH1   . ARG B 2 31  ? 279.212 176.794 174.186 1.00 120.22 ? 34  ARG C NH1   1 
ATOM   3139 N NH2   . ARG B 2 31  ? 280.000 175.581 172.406 1.00 120.22 ? 34  ARG C NH2   1 
ATOM   3140 N N     . THR B 2 32  ? 274.889 171.828 173.350 1.00 117.43 ? 35  THR C N     1 
ATOM   3141 C CA    . THR B 2 32  ? 274.200 170.722 172.694 1.00 117.43 ? 35  THR C CA    1 
ATOM   3142 C C     . THR B 2 32  ? 273.940 169.563 173.649 1.00 117.43 ? 35  THR C C     1 
ATOM   3143 O O     . THR B 2 32  ? 273.857 168.414 173.207 1.00 117.43 ? 35  THR C O     1 
ATOM   3144 C CB    . THR B 2 32  ? 274.986 170.226 171.477 1.00 117.43 ? 35  THR C CB    1 
ATOM   3145 O OG1   . THR B 2 32  ? 276.269 169.750 171.895 1.00 117.43 ? 35  THR C OG1   1 
ATOM   3146 C CG2   . THR B 2 32  ? 275.171 171.342 170.462 1.00 117.43 ? 35  THR C CG2   1 
ATOM   3147 N N     . GLU B 2 33  ? 273.822 169.836 174.947 1.00 112.49 ? 36  GLU C N     1 
ATOM   3148 C CA    . GLU B 2 33  ? 273.476 168.831 175.952 1.00 112.49 ? 36  GLU C CA    1 
ATOM   3149 C C     . GLU B 2 33  ? 272.530 169.497 176.944 1.00 112.49 ? 36  GLU C C     1 
ATOM   3150 O O     . GLU B 2 33  ? 272.963 170.310 177.765 1.00 112.49 ? 36  GLU C O     1 
ATOM   3151 C CB    . GLU B 2 33  ? 274.717 168.284 176.653 1.00 112.49 ? 36  GLU C CB    1 
ATOM   3152 C CG    . GLU B 2 33  ? 275.759 167.674 175.730 1.00 112.49 ? 36  GLU C CG    1 
ATOM   3153 C CD    . GLU B 2 33  ? 275.296 166.376 175.101 1.00 112.49 ? 36  GLU C CD    1 
ATOM   3154 O OE1   . GLU B 2 33  ? 274.710 165.540 175.820 1.00 112.49 ? 36  GLU C OE1   1 
ATOM   3155 O OE2   . GLU B 2 33  ? 275.518 166.191 173.886 1.00 112.49 ? 36  GLU C OE2   1 
ATOM   3156 N N     . CYS B 2 34  ? 271.245 169.162 176.872 1.00 104.31 ? 37  CYS C N     1 
ATOM   3157 C CA    . CYS B 2 34  ? 270.243 169.800 177.715 1.00 104.31 ? 37  CYS C CA    1 
ATOM   3158 C C     . CYS B 2 34  ? 269.185 168.768 178.090 1.00 104.31 ? 37  CYS C C     1 
ATOM   3159 O O     . CYS B 2 34  ? 269.283 167.589 177.736 1.00 104.31 ? 37  CYS C O     1 
ATOM   3160 C CB    . CYS B 2 34  ? 269.632 171.015 177.003 1.00 104.31 ? 37  CYS C CB    1 
ATOM   3161 S SG    . CYS B 2 34  ? 270.801 172.341 176.612 1.00 104.31 ? 37  CYS C SG    1 
ATOM   3162 N N     . PHE B 2 35  ? 268.166 169.223 178.816 1.00 98.32  ? 38  PHE C N     1 
ATOM   3163 C CA    . PHE B 2 35  ? 267.028 168.404 179.210 1.00 98.32  ? 38  PHE C CA    1 
ATOM   3164 C C     . PHE B 2 35  ? 265.780 168.899 178.497 1.00 98.32  ? 38  PHE C C     1 
ATOM   3165 O O     . PHE B 2 35  ? 265.573 170.108 178.359 1.00 98.32  ? 38  PHE C O     1 
ATOM   3166 C CB    . PHE B 2 35  ? 266.793 168.450 180.726 1.00 98.32  ? 38  PHE C CB    1 
ATOM   3167 C CG    . PHE B 2 35  ? 267.844 167.746 181.532 1.00 98.32  ? 38  PHE C CG    1 
ATOM   3168 C CD1   . PHE B 2 35  ? 267.911 166.366 181.552 1.00 98.32  ? 38  PHE C CD1   1 
ATOM   3169 C CD2   . PHE B 2 35  ? 268.753 168.465 182.286 1.00 98.32  ? 38  PHE C CD2   1 
ATOM   3170 C CE1   . PHE B 2 35  ? 268.873 165.719 182.295 1.00 98.32  ? 38  PHE C CE1   1 
ATOM   3171 C CE2   . PHE B 2 35  ? 269.714 167.821 183.029 1.00 98.32  ? 38  PHE C CE2   1 
ATOM   3172 C CZ    . PHE B 2 35  ? 269.773 166.447 183.035 1.00 98.32  ? 38  PHE C CZ    1 
ATOM   3173 N N     . VAL B 2 36  ? 264.948 167.965 178.047 1.00 101.74 ? 39  VAL C N     1 
ATOM   3174 C CA    . VAL B 2 36  ? 263.673 168.310 177.424 1.00 101.74 ? 39  VAL C CA    1 
ATOM   3175 C C     . VAL B 2 36  ? 262.561 167.538 178.125 1.00 101.74 ? 39  VAL C C     1 
ATOM   3176 O O     . VAL B 2 36  ? 262.766 166.384 178.528 1.00 101.74 ? 39  VAL C O     1 
ATOM   3177 C CB    . VAL B 2 36  ? 263.688 168.031 175.911 1.00 101.74 ? 39  VAL C CB    1 
ATOM   3178 C CG1   . VAL B 2 36  ? 264.714 168.907 175.222 1.00 101.74 ? 39  VAL C CG1   1 
ATOM   3179 C CG2   . VAL B 2 36  ? 263.975 166.571 175.635 1.00 101.74 ? 39  VAL C CG2   1 
ATOM   3180 N N     . PRO B 2 37  ? 261.383 168.131 178.308 1.00 101.41 ? 40  PRO C N     1 
ATOM   3181 C CA    . PRO B 2 37  ? 260.304 167.434 179.021 1.00 101.41 ? 40  PRO C CA    1 
ATOM   3182 C C     . PRO B 2 37  ? 259.802 166.193 178.298 1.00 101.41 ? 40  PRO C C     1 
ATOM   3183 O O     . PRO B 2 37  ? 260.220 165.901 177.175 1.00 101.41 ? 40  PRO C O     1 
ATOM   3184 C CB    . PRO B 2 37  ? 259.207 168.501 179.125 1.00 101.41 ? 40  PRO C CB    1 
ATOM   3185 C CG    . PRO B 2 37  ? 259.546 169.513 178.089 1.00 101.41 ? 40  PRO C CG    1 
ATOM   3186 C CD    . PRO B 2 37  ? 261.032 169.526 178.008 1.00 101.41 ? 40  PRO C CD    1 
ATOM   3187 N N     . ASP B 2 38  ? 258.895 165.462 178.939 1.00 103.52 ? 41  ASP C N     1 
ATOM   3188 C CA    . ASP B 2 38  ? 258.392 164.200 178.414 1.00 103.52 ? 41  ASP C CA    1 
ATOM   3189 C C     . ASP B 2 38  ? 257.049 163.920 179.080 1.00 103.52 ? 41  ASP C C     1 
ATOM   3190 O O     . ASP B 2 38  ? 256.568 164.706 179.901 1.00 103.52 ? 41  ASP C O     1 
ATOM   3191 C CB    . ASP B 2 38  ? 259.407 163.075 178.650 1.00 103.52 ? 41  ASP C CB    1 
ATOM   3192 C CG    . ASP B 2 38  ? 259.026 161.782 177.959 1.00 103.52 ? 41  ASP C CG    1 
ATOM   3193 O OD1   . ASP B 2 38  ? 259.392 161.605 176.780 1.00 103.52 ? 41  ASP C OD1   1 
ATOM   3194 O OD2   . ASP B 2 38  ? 258.354 160.946 178.597 1.00 103.52 ? 41  ASP C OD2   1 
ATOM   3195 N N     . ASP B 2 39  ? 256.439 162.794 178.715 1.00 106.57 ? 42  ASP C N     1 
ATOM   3196 C CA    . ASP B 2 39  ? 255.148 162.379 179.251 1.00 106.57 ? 42  ASP C CA    1 
ATOM   3197 C C     . ASP B 2 39  ? 255.227 161.178 180.179 1.00 106.57 ? 42  ASP C C     1 
ATOM   3198 O O     . ASP B 2 39  ? 254.530 161.146 181.194 1.00 106.57 ? 42  ASP C O     1 
ATOM   3199 C CB    . ASP B 2 39  ? 254.178 162.068 178.104 1.00 106.57 ? 42  ASP C CB    1 
ATOM   3200 C CG    . ASP B 2 39  ? 254.671 160.947 177.206 1.00 106.57 ? 42  ASP C CG    1 
ATOM   3201 O OD1   . ASP B 2 39  ? 255.006 161.227 176.037 1.00 106.57 ? 42  ASP C OD1   1 
ATOM   3202 O OD2   . ASP B 2 39  ? 254.719 159.786 177.661 1.00 106.57 ? 42  ASP C OD2   1 
ATOM   3203 N N     . LYS B 2 40  ? 256.053 160.182 179.858 1.00 104.85 ? 43  LYS C N     1 
ATOM   3204 C CA    . LYS B 2 40  ? 256.157 158.975 180.669 1.00 104.85 ? 43  LYS C CA    1 
ATOM   3205 C C     . LYS B 2 40  ? 257.362 158.982 181.597 1.00 104.85 ? 43  LYS C C     1 
ATOM   3206 O O     . LYS B 2 40  ? 257.285 158.431 182.699 1.00 104.85 ? 43  LYS C O     1 
ATOM   3207 C CB    . LYS B 2 40  ? 256.214 157.735 179.769 1.00 104.85 ? 43  LYS C CB    1 
ATOM   3208 C CG    . LYS B 2 40  ? 257.396 157.707 178.812 1.00 104.85 ? 43  LYS C CG    1 
ATOM   3209 C CD    . LYS B 2 40  ? 257.257 156.596 177.790 1.00 104.85 ? 43  LYS C CD    1 
ATOM   3210 C CE    . LYS B 2 40  ? 256.206 156.939 176.751 1.00 104.85 ? 43  LYS C CE    1 
ATOM   3211 N NZ    . LYS B 2 40  ? 256.552 158.180 176.006 1.00 104.85 ? 43  LYS C NZ    1 
ATOM   3212 N N     . GLU B 2 41  ? 258.470 159.586 181.174 1.00 100.06 ? 44  GLU C N     1 
ATOM   3213 C CA    . GLU B 2 41  ? 259.608 159.826 182.045 1.00 100.06 ? 44  GLU C CA    1 
ATOM   3214 C C     . GLU B 2 41  ? 259.663 161.265 182.532 1.00 100.06 ? 44  GLU C C     1 
ATOM   3215 O O     . GLU B 2 41  ? 260.456 161.575 183.426 1.00 100.06 ? 44  GLU C O     1 
ATOM   3216 C CB    . GLU B 2 41  ? 260.911 159.476 181.315 1.00 100.06 ? 44  GLU C CB    1 
ATOM   3217 C CG    . GLU B 2 41  ? 262.061 159.078 182.220 1.00 100.06 ? 44  GLU C CG    1 
ATOM   3218 C CD    . GLU B 2 41  ? 263.302 158.699 181.439 1.00 100.06 ? 44  GLU C CD    1 
ATOM   3219 O OE1   . GLU B 2 41  ? 263.207 158.563 180.203 1.00 100.06 ? 44  GLU C OE1   1 
ATOM   3220 O OE2   . GLU B 2 41  ? 264.374 158.537 182.059 1.00 100.06 ? 44  GLU C OE2   1 
ATOM   3221 N N     . GLU B 2 42  ? 258.867 162.145 181.926 1.00 99.30  ? 45  GLU C N     1 
ATOM   3222 C CA    . GLU B 2 42  ? 258.639 163.520 182.358 1.00 99.30  ? 45  GLU C CA    1 
ATOM   3223 C C     . GLU B 2 42  ? 259.873 164.398 182.182 1.00 99.30  ? 45  GLU C C     1 
ATOM   3224 O O     . GLU B 2 42  ? 259.761 165.627 182.202 1.00 99.30  ? 45  GLU C O     1 
ATOM   3225 C CB    . GLU B 2 42  ? 258.171 163.538 183.819 1.00 99.30  ? 45  GLU C CB    1 
ATOM   3226 C CG    . GLU B 2 42  ? 257.788 164.911 184.357 1.00 99.30  ? 45  GLU C CG    1 
ATOM   3227 C CD    . GLU B 2 42  ? 257.308 164.868 185.793 1.00 99.30  ? 45  GLU C CD    1 
ATOM   3228 O OE1   . GLU B 2 42  ? 257.281 163.767 186.380 1.00 99.30  ? 45  GLU C OE1   1 
ATOM   3229 O OE2   . GLU B 2 42  ? 256.959 165.937 186.335 1.00 99.30  ? 45  GLU C OE2   1 
ATOM   3230 N N     . TYR B 2 43  ? 261.027 163.788 181.909 1.00 98.07  ? 46  TYR C N     1 
ATOM   3231 C CA    . TYR B 2 43  ? 262.282 164.503 181.696 1.00 98.07  ? 46  TYR C CA    1 
ATOM   3232 C C     . TYR B 2 43  ? 263.315 163.546 181.122 1.00 98.07  ? 46  TYR C C     1 
ATOM   3233 O O     . TYR B 2 43  ? 263.532 162.465 181.676 1.00 98.07  ? 46  TYR C O     1 
ATOM   3234 C CB    . TYR B 2 43  ? 262.808 165.110 182.998 1.00 98.07  ? 46  TYR C CB    1 
ATOM   3235 C CG    . TYR B 2 43  ? 262.158 166.415 183.389 1.00 98.07  ? 46  TYR C CG    1 
ATOM   3236 C CD1   . TYR B 2 43  ? 262.059 167.464 182.486 1.00 98.07  ? 46  TYR C CD1   1 
ATOM   3237 C CD2   . TYR B 2 43  ? 261.631 166.593 184.661 1.00 98.07  ? 46  TYR C CD2   1 
ATOM   3238 C CE1   . TYR B 2 43  ? 261.457 168.654 182.841 1.00 98.07  ? 46  TYR C CE1   1 
ATOM   3239 C CE2   . TYR B 2 43  ? 261.032 167.779 185.026 1.00 98.07  ? 46  TYR C CE2   1 
ATOM   3240 C CZ    . TYR B 2 43  ? 260.947 168.807 184.114 1.00 98.07  ? 46  TYR C CZ    1 
ATOM   3241 O OH    . TYR B 2 43  ? 260.347 169.991 184.476 1.00 98.07  ? 46  TYR C OH    1 
ATOM   3242 N N     . VAL B 2 44  ? 263.964 163.926 180.019 1.00 99.13  ? 47  VAL C N     1 
ATOM   3243 C CA    . VAL B 2 44  ? 264.954 163.076 179.370 1.00 99.13  ? 47  VAL C CA    1 
ATOM   3244 C C     . VAL B 2 44  ? 266.146 163.917 178.938 1.00 99.13  ? 47  VAL C C     1 
ATOM   3245 O O     . VAL B 2 44  ? 266.049 165.130 178.745 1.00 99.13  ? 47  VAL C O     1 
ATOM   3246 C CB    . VAL B 2 44  ? 264.380 162.320 178.151 1.00 99.13  ? 47  VAL C CB    1 
ATOM   3247 C CG1   . VAL B 2 44  ? 263.295 161.353 178.579 1.00 99.13  ? 47  VAL C CG1   1 
ATOM   3248 C CG2   . VAL B 2 44  ? 263.843 163.297 177.129 1.00 99.13  ? 47  VAL C CG2   1 
ATOM   3249 N N     . LYS B 2 45  ? 267.284 163.245 178.792 1.00 103.73 ? 48  LYS C N     1 
ATOM   3250 C CA    . LYS B 2 45  ? 268.480 163.870 178.252 1.00 103.73 ? 48  LYS C CA    1 
ATOM   3251 C C     . LYS B 2 45  ? 268.377 163.962 176.737 1.00 103.73 ? 48  LYS C C     1 
ATOM   3252 O O     . LYS B 2 45  ? 267.777 163.108 176.084 1.00 103.73 ? 48  LYS C O     1 
ATOM   3253 C CB    . LYS B 2 45  ? 269.728 163.074 178.635 1.00 103.73 ? 48  LYS C CB    1 
ATOM   3254 C CG    . LYS B 2 45  ? 269.939 162.911 180.125 1.00 103.73 ? 48  LYS C CG    1 
ATOM   3255 C CD    . LYS B 2 45  ? 271.337 162.400 180.426 1.00 103.73 ? 48  LYS C CD    1 
ATOM   3256 C CE    . LYS B 2 45  ? 271.608 162.392 181.917 1.00 103.73 ? 48  LYS C CE    1 
ATOM   3257 N NZ    . LYS B 2 45  ? 273.058 162.277 182.217 1.00 103.73 ? 48  LYS C NZ    1 
ATOM   3258 N N     . ALA B 2 46  ? 268.972 165.010 176.176 1.00 110.77 ? 49  ALA C N     1 
ATOM   3259 C CA    . ALA B 2 46  ? 268.854 165.251 174.748 1.00 110.77 ? 49  ALA C CA    1 
ATOM   3260 C C     . ALA B 2 46  ? 270.074 166.016 174.261 1.00 110.77 ? 49  ALA C C     1 
ATOM   3261 O O     . ALA B 2 46  ? 270.876 166.518 175.051 1.00 110.77 ? 49  ALA C O     1 
ATOM   3262 C CB    . ALA B 2 46  ? 267.569 166.014 174.422 1.00 110.77 ? 49  ALA C CB    1 
ATOM   3263 N N     . LYS B 2 47  ? 270.201 166.098 172.940 1.00 114.17 ? 50  LYS C N     1 
ATOM   3264 C CA    . LYS B 2 47  ? 271.275 166.860 172.316 1.00 114.17 ? 50  LYS C CA    1 
ATOM   3265 C C     . LYS B 2 47  ? 270.733 168.118 171.648 1.00 114.17 ? 50  LYS C C     1 
ATOM   3266 O O     . LYS B 2 47  ? 270.206 168.062 170.539 1.00 114.17 ? 50  LYS C O     1 
ATOM   3267 C CB    . LYS B 2 47  ? 272.023 166.007 171.292 1.00 114.17 ? 50  LYS C CB    1 
ATOM   3268 C CG    . LYS B 2 47  ? 273.130 165.141 171.879 1.00 114.17 ? 50  LYS C CG    1 
ATOM   3269 C CD    . LYS B 2 47  ? 272.579 163.918 172.597 1.00 114.17 ? 50  LYS C CD    1 
ATOM   3270 C CE    . LYS B 2 47  ? 271.992 162.923 171.610 1.00 114.17 ? 50  LYS C CE    1 
ATOM   3271 N NZ    . LYS B 2 47  ? 271.492 161.697 172.285 1.00 114.17 ? 50  LYS C NZ    1 
ATOM   3272 N N     . ALA B 2 58  ? 263.613 172.916 169.159 1.00 128.31 ? 61  ALA C N     1 
ATOM   3273 C CA    . ALA B 2 58  ? 264.953 172.618 168.671 1.00 128.31 ? 61  ALA C CA    1 
ATOM   3274 C C     . ALA B 2 58  ? 265.116 171.127 168.402 1.00 128.31 ? 61  ALA C C     1 
ATOM   3275 O O     . ALA B 2 58  ? 264.407 170.301 168.974 1.00 128.31 ? 61  ALA C O     1 
ATOM   3276 C CB    . ALA B 2 58  ? 265.999 173.095 169.667 1.00 128.31 ? 61  ALA C CB    1 
ATOM   3277 N N     . GLU B 2 59  ? 266.055 170.790 167.523 1.00 130.84 ? 62  GLU C N     1 
ATOM   3278 C CA    . GLU B 2 59  ? 266.312 169.394 167.192 1.00 130.84 ? 62  GLU C CA    1 
ATOM   3279 C C     . GLU B 2 59  ? 266.976 168.692 168.374 1.00 130.84 ? 62  GLU C C     1 
ATOM   3280 O O     . GLU B 2 59  ? 268.080 169.058 168.792 1.00 130.84 ? 62  GLU C O     1 
ATOM   3281 C CB    . GLU B 2 59  ? 267.161 169.298 165.920 1.00 130.84 ? 62  GLU C CB    1 
ATOM   3282 C CG    . GLU B 2 59  ? 268.604 169.810 166.014 1.00 130.84 ? 62  GLU C CG    1 
ATOM   3283 C CD    . GLU B 2 59  ? 268.725 171.309 165.788 1.00 130.84 ? 62  GLU C CD    1 
ATOM   3284 O OE1   . GLU B 2 59  ? 267.682 171.992 165.722 1.00 130.84 ? 62  GLU C OE1   1 
ATOM   3285 O OE2   . GLU B 2 59  ? 269.866 171.805 165.684 1.00 130.84 ? 62  GLU C OE2   1 
ATOM   3286 N N     . THR B 2 60  ? 266.276 167.719 168.953 1.00 126.77 ? 63  THR C N     1 
ATOM   3287 C CA    . THR B 2 60  ? 266.797 166.938 170.065 1.00 126.77 ? 63  THR C CA    1 
ATOM   3288 C C     . THR B 2 60  ? 266.470 165.474 169.827 1.00 126.77 ? 63  THR C C     1 
ATOM   3289 O O     . THR B 2 60  ? 265.475 165.155 169.172 1.00 126.77 ? 63  THR C O     1 
ATOM   3290 C CB    . THR B 2 60  ? 266.210 167.383 171.411 1.00 126.77 ? 63  THR C CB    1 
ATOM   3291 O OG1   . THR B 2 60  ? 264.896 166.832 171.568 1.00 126.77 ? 63  THR C OG1   1 
ATOM   3292 C CG2   . THR B 2 60  ? 266.140 168.903 171.511 1.00 126.77 ? 63  THR C CG2   1 
ATOM   3293 N N     . GLU B 2 61  ? 267.306 164.586 170.362 1.00 126.02 ? 64  GLU C N     1 
ATOM   3294 C CA    . GLU B 2 61  ? 267.136 163.158 170.134 1.00 126.02 ? 64  GLU C CA    1 
ATOM   3295 C C     . GLU B 2 61  ? 267.659 162.360 171.318 1.00 126.02 ? 64  GLU C C     1 
ATOM   3296 O O     . GLU B 2 61  ? 268.776 162.598 171.787 1.00 126.02 ? 64  GLU C O     1 
ATOM   3297 C CB    . GLU B 2 61  ? 267.859 162.725 168.854 1.00 126.02 ? 64  GLU C CB    1 
ATOM   3298 C CG    . GLU B 2 61  ? 267.721 161.251 168.532 1.00 126.02 ? 64  GLU C CG    1 
ATOM   3299 C CD    . GLU B 2 61  ? 266.331 160.891 168.052 1.00 126.02 ? 64  GLU C CD    1 
ATOM   3300 O OE1   . GLU B 2 61  ? 265.918 159.731 168.244 1.00 126.02 ? 64  GLU C OE1   1 
ATOM   3301 O OE2   . GLU B 2 61  ? 265.651 161.767 167.482 1.00 126.02 ? 64  GLU C OE2   1 
ATOM   3302 N N     . ASN B 2 62  ? 266.840 161.419 171.803 1.00 123.75 ? 65  ASN C N     1 
ATOM   3303 C CA    . ASN B 2 62  ? 267.300 160.408 172.748 1.00 123.75 ? 65  ASN C CA    1 
ATOM   3304 C C     . ASN B 2 62  ? 266.682 159.044 172.458 1.00 123.75 ? 65  ASN C C     1 
ATOM   3305 O O     . ASN B 2 62  ? 266.425 158.276 173.394 1.00 123.75 ? 65  ASN C O     1 
ATOM   3306 C CB    . ASN B 2 62  ? 266.996 160.809 174.189 1.00 123.75 ? 65  ASN C CB    1 
ATOM   3307 C CG    . ASN B 2 62  ? 267.967 160.193 175.178 1.00 123.75 ? 65  ASN C CG    1 
ATOM   3308 O OD1   . ASN B 2 62  ? 269.160 160.493 175.161 1.00 123.75 ? 65  ASN C OD1   1 
ATOM   3309 N ND2   . ASN B 2 62  ? 267.460 159.325 176.045 1.00 123.75 ? 65  ASN C ND2   1 
ATOM   3310 N N     . GLY B 2 63  ? 266.430 158.728 171.193 1.00 127.01 ? 66  GLY C N     1 
ATOM   3311 C CA    . GLY B 2 63  ? 265.681 157.544 170.827 1.00 127.01 ? 66  GLY C CA    1 
ATOM   3312 C C     . GLY B 2 63  ? 264.448 157.954 170.052 1.00 127.01 ? 66  GLY C C     1 
ATOM   3313 O O     . GLY B 2 63  ? 263.901 157.180 169.262 1.00 127.01 ? 66  GLY C O     1 
ATOM   3314 N N     . LYS B 2 64  ? 264.023 159.198 170.270 1.00 126.88 ? 67  LYS C N     1 
ATOM   3315 C CA    . LYS B 2 64  ? 262.913 159.811 169.558 1.00 126.88 ? 67  LYS C CA    1 
ATOM   3316 C C     . LYS B 2 64  ? 263.242 161.280 169.344 1.00 126.88 ? 67  LYS C C     1 
ATOM   3317 O O     . LYS B 2 64  ? 264.088 161.846 170.039 1.00 126.88 ? 67  LYS C O     1 
ATOM   3318 C CB    . LYS B 2 64  ? 261.590 159.671 170.320 1.00 126.88 ? 67  LYS C CB    1 
ATOM   3319 C CG    . LYS B 2 64  ? 261.057 158.249 170.421 1.00 126.88 ? 67  LYS C CG    1 
ATOM   3320 C CD    . LYS B 2 64  ? 260.841 157.626 169.050 1.00 126.88 ? 67  LYS C CD    1 
ATOM   3321 C CE    . LYS B 2 64  ? 259.895 158.452 168.197 1.00 126.88 ? 67  LYS C CE    1 
ATOM   3322 N NZ    . LYS B 2 64  ? 259.820 157.924 166.809 1.00 126.88 ? 67  LYS C NZ    1 
ATOM   3323 N N     . THR B 2 65  ? 262.574 161.890 168.372 1.00 128.56 ? 68  THR C N     1 
ATOM   3324 C CA    . THR B 2 65  ? 262.820 163.279 168.009 1.00 128.56 ? 68  THR C CA    1 
ATOM   3325 C C     . THR B 2 65  ? 261.668 164.151 168.491 1.00 128.56 ? 68  THR C C     1 
ATOM   3326 O O     . THR B 2 65  ? 260.501 163.765 168.375 1.00 128.56 ? 68  THR C O     1 
ATOM   3327 C CB    . THR B 2 65  ? 262.996 163.416 166.495 1.00 128.56 ? 68  THR C CB    1 
ATOM   3328 O OG1   . THR B 2 65  ? 264.149 162.672 166.080 1.00 128.56 ? 68  THR C OG1   1 
ATOM   3329 C CG2   . THR B 2 65  ? 263.176 164.874 166.097 1.00 128.56 ? 68  THR C CG2   1 
ATOM   3330 N N     . VAL B 2 66  ? 261.999 165.320 169.035 1.00 128.18 ? 69  VAL C N     1 
ATOM   3331 C CA    . VAL B 2 66  ? 261.004 166.295 169.458 1.00 128.18 ? 69  VAL C CA    1 
ATOM   3332 C C     . VAL B 2 66  ? 261.589 167.689 169.273 1.00 128.18 ? 69  VAL C C     1 
ATOM   3333 O O     . VAL B 2 66  ? 262.796 167.903 169.422 1.00 128.18 ? 69  VAL C O     1 
ATOM   3334 C CB    . VAL B 2 66  ? 260.556 166.059 170.921 1.00 128.18 ? 69  VAL C CB    1 
ATOM   3335 C CG1   . VAL B 2 66  ? 261.723 166.231 171.881 1.00 128.18 ? 69  VAL C CG1   1 
ATOM   3336 C CG2   . VAL B 2 66  ? 259.398 166.976 171.294 1.00 128.18 ? 69  VAL C CG2   1 
ATOM   3337 N N     . THR B 2 67  ? 260.724 168.640 168.925 1.00 128.38 ? 70  THR C N     1 
ATOM   3338 C CA    . THR B 2 67  ? 261.120 170.030 168.716 1.00 128.38 ? 70  THR C CA    1 
ATOM   3339 C C     . THR B 2 67  ? 260.236 170.910 169.587 1.00 128.38 ? 70  THR C C     1 
ATOM   3340 O O     . THR B 2 67  ? 259.026 171.000 169.357 1.00 128.38 ? 70  THR C O     1 
ATOM   3341 C CB    . THR B 2 67  ? 261.005 170.430 167.243 1.00 128.38 ? 70  THR C CB    1 
ATOM   3342 O OG1   . THR B 2 67  ? 259.754 169.973 166.716 1.00 128.38 ? 70  THR C OG1   1 
ATOM   3343 C CG2   . THR B 2 67  ? 262.141 169.825 166.434 1.00 128.38 ? 70  THR C CG2   1 
ATOM   3344 N N     . ILE B 2 68  ? 260.838 171.556 170.582 1.00 125.37 ? 71  ILE C N     1 
ATOM   3345 C CA    . ILE B 2 68  ? 260.093 172.385 171.521 1.00 125.37 ? 71  ILE C CA    1 
ATOM   3346 C C     . ILE B 2 68  ? 260.668 173.794 171.522 1.00 125.37 ? 71  ILE C C     1 
ATOM   3347 O O     . ILE B 2 68  ? 261.627 174.087 170.800 1.00 125.37 ? 71  ILE C O     1 
ATOM   3348 C CB    . ILE B 2 68  ? 260.115 171.778 172.935 1.00 125.37 ? 71  ILE C CB    1 
ATOM   3349 C CG1   . ILE B 2 68  ? 261.553 171.663 173.439 1.00 125.37 ? 71  ILE C CG1   1 
ATOM   3350 C CG2   . ILE B 2 68  ? 259.437 170.420 172.945 1.00 125.37 ? 71  ILE C CG2   1 
ATOM   3351 C CD1   . ILE B 2 68  ? 261.653 171.290 174.893 1.00 125.37 ? 71  ILE C CD1   1 
ATOM   3352 N N     . LYS B 2 69  ? 260.085 174.672 172.333 1.00 124.33 ? 72  LYS C N     1 
ATOM   3353 C CA    . LYS B 2 69  ? 260.520 176.059 172.377 1.00 124.33 ? 72  LYS C CA    1 
ATOM   3354 C C     . LYS B 2 69  ? 261.940 176.171 172.916 1.00 124.33 ? 72  LYS C C     1 
ATOM   3355 O O     . LYS B 2 69  ? 262.398 175.343 173.708 1.00 124.33 ? 72  LYS C O     1 
ATOM   3356 C CB    . LYS B 2 69  ? 259.562 176.891 173.229 1.00 124.33 ? 72  LYS C CB    1 
ATOM   3357 C CG    . LYS B 2 69  ? 258.134 176.966 172.687 1.00 124.33 ? 72  LYS C CG    1 
ATOM   3358 C CD    . LYS B 2 69  ? 258.039 177.854 171.446 1.00 124.33 ? 72  LYS C CD    1 
ATOM   3359 C CE    . LYS B 2 69  ? 258.090 177.050 170.150 1.00 124.33 ? 72  LYS C CE    1 
ATOM   3360 N NZ    . LYS B 2 69  ? 257.926 177.911 168.947 1.00 124.33 ? 72  LYS C NZ    1 
ATOM   3361 N N     . GLU B 2 70  ? 262.640 177.215 172.474 1.00 124.82 ? 73  GLU C N     1 
ATOM   3362 C CA    . GLU B 2 70  ? 264.034 177.429 172.829 1.00 124.82 ? 73  GLU C CA    1 
ATOM   3363 C C     . GLU B 2 70  ? 264.192 178.195 174.138 1.00 124.82 ? 73  GLU C C     1 
ATOM   3364 O O     . GLU B 2 70  ? 265.252 178.781 174.382 1.00 124.82 ? 73  GLU C O     1 
ATOM   3365 C CB    . GLU B 2 70  ? 264.761 178.153 171.694 1.00 124.82 ? 73  GLU C CB    1 
ATOM   3366 C CG    . GLU B 2 70  ? 266.245 177.830 171.598 1.00 124.82 ? 73  GLU C CG    1 
ATOM   3367 C CD    . GLU B 2 70  ? 266.915 178.514 170.424 1.00 124.82 ? 73  GLU C CD    1 
ATOM   3368 O OE1   . GLU B 2 70  ? 266.487 178.280 169.274 1.00 124.82 ? 73  GLU C OE1   1 
ATOM   3369 O OE2   . GLU B 2 70  ? 267.870 179.286 170.652 1.00 124.82 ? 73  GLU C OE2   1 
ATOM   3370 N N     . ASP B 2 71  ? 263.158 178.208 174.979 1.00 122.85 ? 74  ASP C N     1 
ATOM   3371 C CA    . ASP B 2 71  ? 263.265 178.701 176.347 1.00 122.85 ? 74  ASP C CA    1 
ATOM   3372 C C     . ASP B 2 71  ? 262.606 177.730 177.318 1.00 122.85 ? 74  ASP C C     1 
ATOM   3373 O O     . ASP B 2 71  ? 262.090 178.135 178.362 1.00 122.85 ? 74  ASP C O     1 
ATOM   3374 C CB    . ASP B 2 71  ? 262.665 180.099 176.483 1.00 122.85 ? 74  ASP C CB    1 
ATOM   3375 C CG    . ASP B 2 71  ? 263.722 181.187 176.476 1.00 122.85 ? 74  ASP C CG    1 
ATOM   3376 O OD1   . ASP B 2 71  ? 264.901 180.871 176.213 1.00 122.85 ? 74  ASP C OD1   1 
ATOM   3377 O OD2   . ASP B 2 71  ? 263.376 182.358 176.738 1.00 122.85 ? 74  ASP C OD2   1 
ATOM   3378 N N     . GLN B 2 72  ? 262.618 176.442 176.977 1.00 116.16 ? 75  GLN C N     1 
ATOM   3379 C CA    . GLN B 2 72  ? 262.186 175.390 177.879 1.00 116.16 ? 75  GLN C CA    1 
ATOM   3380 C C     . GLN B 2 72  ? 263.213 174.273 177.988 1.00 116.16 ? 75  GLN C C     1 
ATOM   3381 O O     . GLN B 2 72  ? 262.945 173.269 178.656 1.00 116.16 ? 75  GLN C O     1 
ATOM   3382 C CB    . GLN B 2 72  ? 260.836 174.809 177.429 1.00 116.16 ? 75  GLN C CB    1 
ATOM   3383 C CG    . GLN B 2 72  ? 259.999 174.234 178.557 1.00 116.16 ? 75  GLN C CG    1 
ATOM   3384 C CD    . GLN B 2 72  ? 258.532 174.120 178.200 1.00 116.16 ? 75  GLN C CD    1 
ATOM   3385 O OE1   . GLN B 2 72  ? 258.133 174.391 177.068 1.00 116.16 ? 75  GLN C OE1   1 
ATOM   3386 N NE2   . GLN B 2 72  ? 257.719 173.715 179.168 1.00 116.16 ? 75  GLN C NE2   1 
ATOM   3387 N N     . VAL B 2 73  ? 264.371 174.416 177.354 1.00 110.50 ? 76  VAL C N     1 
ATOM   3388 C CA    . VAL B 2 73  ? 265.457 173.455 177.487 1.00 110.50 ? 76  VAL C CA    1 
ATOM   3389 C C     . VAL B 2 73  ? 266.452 173.981 178.514 1.00 110.50 ? 76  VAL C C     1 
ATOM   3390 O O     . VAL B 2 73  ? 266.928 175.119 178.416 1.00 110.50 ? 76  VAL C O     1 
ATOM   3391 C CB    . VAL B 2 73  ? 266.128 173.181 176.128 1.00 110.50 ? 76  VAL C CB    1 
ATOM   3392 C CG1   . VAL B 2 73  ? 265.115 172.610 175.155 1.00 110.50 ? 76  VAL C CG1   1 
ATOM   3393 C CG2   . VAL B 2 73  ? 266.740 174.448 175.541 1.00 110.50 ? 76  VAL C CG2   1 
ATOM   3394 N N     . MET B 2 74  ? 266.734 173.167 179.525 1.00 102.30 ? 77  MET C N     1 
ATOM   3395 C CA    . MET B 2 74  ? 267.681 173.513 180.574 1.00 102.30 ? 77  MET C CA    1 
ATOM   3396 C C     . MET B 2 74  ? 268.951 172.706 180.366 1.00 102.30 ? 77  MET C C     1 
ATOM   3397 O O     . MET B 2 74  ? 268.886 171.505 180.084 1.00 102.30 ? 77  MET C O     1 
ATOM   3398 C CB    . MET B 2 74  ? 267.093 173.235 181.958 1.00 102.30 ? 77  MET C CB    1 
ATOM   3399 C CG    . MET B 2 74  ? 266.058 174.246 182.408 1.00 102.30 ? 77  MET C CG    1 
ATOM   3400 S SD    . MET B 2 74  ? 264.507 174.053 181.518 1.00 102.30 ? 77  MET C SD    1 
ATOM   3401 C CE    . MET B 2 74  ? 263.889 172.541 182.247 1.00 102.30 ? 77  MET C CE    1 
ATOM   3402 N N     . GLN B 2 75  ? 270.098 173.360 180.509 1.00 98.37  ? 78  GLN C N     1 
ATOM   3403 C CA    . GLN B 2 75  ? 271.362 172.699 180.223 1.00 98.37  ? 78  GLN C CA    1 
ATOM   3404 C C     . GLN B 2 75  ? 271.716 171.712 181.325 1.00 98.37  ? 78  GLN C C     1 
ATOM   3405 O O     . GLN B 2 75  ? 271.497 171.974 182.510 1.00 98.37  ? 78  GLN C O     1 
ATOM   3406 C CB    . GLN B 2 75  ? 272.477 173.730 180.073 1.00 98.37  ? 78  GLN C CB    1 
ATOM   3407 C CG    . GLN B 2 75  ? 272.057 174.992 179.352 1.00 98.37  ? 78  GLN C CG    1 
ATOM   3408 C CD    . GLN B 2 75  ? 273.110 176.074 179.428 1.00 98.37  ? 78  GLN C CD    1 
ATOM   3409 O OE1   . GLN B 2 75  ? 274.299 175.811 179.261 1.00 98.37  ? 78  GLN C OE1   1 
ATOM   3410 N NE2   . GLN B 2 75  ? 272.678 177.302 179.686 1.00 98.37  ? 78  GLN C NE2   1 
ATOM   3411 N N     . GLN B 2 76  ? 272.260 170.567 180.926 1.00 98.09  ? 79  GLN C N     1 
ATOM   3412 C CA    . GLN B 2 76  ? 272.811 169.637 181.897 1.00 98.09  ? 79  GLN C CA    1 
ATOM   3413 C C     . GLN B 2 76  ? 273.999 170.274 182.605 1.00 98.09  ? 79  GLN C C     1 
ATOM   3414 O O     . GLN B 2 76  ? 274.697 171.126 182.051 1.00 98.09  ? 79  GLN C O     1 
ATOM   3415 C CB    . GLN B 2 76  ? 273.253 168.340 181.219 1.00 98.09  ? 79  GLN C CB    1 
ATOM   3416 C CG    . GLN B 2 76  ? 272.161 167.603 180.478 1.00 98.09  ? 79  GLN C CG    1 
ATOM   3417 C CD    . GLN B 2 76  ? 272.560 166.183 180.132 1.00 98.09  ? 79  GLN C CD    1 
ATOM   3418 O OE1   . GLN B 2 76  ? 273.526 165.651 180.675 1.00 98.09  ? 79  GLN C OE1   1 
ATOM   3419 N NE2   . GLN B 2 76  ? 271.818 165.563 179.224 1.00 98.09  ? 79  GLN C NE2   1 
ATOM   3420 N N     . ASN B 2 77  ? 274.224 169.858 183.844 1.00 94.29  ? 80  ASN C N     1 
ATOM   3421 C CA    . ASN B 2 77  ? 275.401 170.315 184.554 1.00 94.29  ? 80  ASN C CA    1 
ATOM   3422 C C     . ASN B 2 77  ? 276.645 169.666 183.952 1.00 94.29  ? 80  ASN C C     1 
ATOM   3423 O O     . ASN B 2 77  ? 276.603 168.511 183.520 1.00 94.29  ? 80  ASN C O     1 
ATOM   3424 C CB    . ASN B 2 77  ? 275.301 169.982 186.039 1.00 94.29  ? 80  ASN C CB    1 
ATOM   3425 C CG    . ASN B 2 77  ? 274.416 170.950 186.790 1.00 94.29  ? 80  ASN C CG    1 
ATOM   3426 O OD1   . ASN B 2 77  ? 274.879 171.976 187.281 1.00 94.29  ? 80  ASN C OD1   1 
ATOM   3427 N ND2   . ASN B 2 77  ? 273.133 170.627 186.886 1.00 94.29  ? 80  ASN C ND2   1 
ATOM   3428 N N     . PRO B 2 78  ? 277.756 170.393 183.895 1.00 95.35  ? 81  PRO C N     1 
ATOM   3429 C CA    . PRO B 2 78  ? 278.986 169.839 183.324 1.00 95.35  ? 81  PRO C CA    1 
ATOM   3430 C C     . PRO B 2 78  ? 279.409 168.576 184.051 1.00 95.35  ? 81  PRO C C     1 
ATOM   3431 O O     . PRO B 2 78  ? 278.941 168.305 185.167 1.00 95.35  ? 81  PRO C O     1 
ATOM   3432 C CB    . PRO B 2 78  ? 280.004 170.971 183.530 1.00 95.35  ? 81  PRO C CB    1 
ATOM   3433 C CG    . PRO B 2 78  ? 279.184 172.202 183.595 1.00 95.35  ? 81  PRO C CG    1 
ATOM   3434 C CD    . PRO B 2 78  ? 277.908 171.809 184.268 1.00 95.35  ? 81  PRO C CD    1 
ATOM   3435 N N     . PRO B 2 79  ? 280.296 167.772 183.457 1.00 100.76 ? 82  PRO C N     1 
ATOM   3436 C CA    . PRO B 2 79  ? 280.778 166.571 184.155 1.00 100.76 ? 82  PRO C CA    1 
ATOM   3437 C C     . PRO B 2 79  ? 281.581 166.875 185.407 1.00 100.76 ? 82  PRO C C     1 
ATOM   3438 O O     . PRO B 2 79  ? 281.860 165.949 186.180 1.00 100.76 ? 82  PRO C O     1 
ATOM   3439 C CB    . PRO B 2 79  ? 281.641 165.875 183.097 1.00 100.76 ? 82  PRO C CB    1 
ATOM   3440 C CG    . PRO B 2 79  ? 282.082 166.977 182.203 1.00 100.76 ? 82  PRO C CG    1 
ATOM   3441 C CD    . PRO B 2 79  ? 280.920 167.920 182.132 1.00 100.76 ? 82  PRO C CD    1 
ATOM   3442 N N     . LYS B 2 80  ? 281.963 168.134 185.631 1.00 98.55  ? 83  LYS C N     1 
ATOM   3443 C CA    . LYS B 2 80  ? 282.594 168.521 186.885 1.00 98.55  ? 83  LYS C CA    1 
ATOM   3444 C C     . LYS B 2 80  ? 281.609 168.498 188.046 1.00 98.55  ? 83  LYS C C     1 
ATOM   3445 O O     . LYS B 2 80  ? 282.033 168.507 189.205 1.00 98.55  ? 83  LYS C O     1 
ATOM   3446 C CB    . LYS B 2 80  ? 283.212 169.911 186.746 1.00 98.55  ? 83  LYS C CB    1 
ATOM   3447 C CG    . LYS B 2 80  ? 284.310 169.984 185.693 1.00 98.55  ? 83  LYS C CG    1 
ATOM   3448 C CD    . LYS B 2 80  ? 284.908 171.379 185.588 1.00 98.55  ? 83  LYS C CD    1 
ATOM   3449 C CE    . LYS B 2 80  ? 283.939 172.352 184.936 1.00 98.55  ? 83  LYS C CE    1 
ATOM   3450 N NZ    . LYS B 2 80  ? 283.682 172.011 183.512 1.00 98.55  ? 83  LYS C NZ    1 
ATOM   3451 N N     . PHE B 2 81  ? 280.309 168.484 187.760 1.00 93.17  ? 84  PHE C N     1 
ATOM   3452 C CA    . PHE B 2 81  ? 279.266 168.371 188.770 1.00 93.17  ? 84  PHE C CA    1 
ATOM   3453 C C     . PHE B 2 81  ? 278.378 167.156 188.527 1.00 93.17  ? 84  PHE C C     1 
ATOM   3454 O O     . PHE B 2 81  ? 277.152 167.258 188.595 1.00 93.17  ? 84  PHE C O     1 
ATOM   3455 C CB    . PHE B 2 81  ? 278.411 169.636 188.809 1.00 93.17  ? 84  PHE C CB    1 
ATOM   3456 C CG    . PHE B 2 81  ? 279.200 170.906 188.875 1.00 93.17  ? 84  PHE C CG    1 
ATOM   3457 C CD1   . PHE B 2 81  ? 279.704 171.362 190.078 1.00 93.17  ? 84  PHE C CD1   1 
ATOM   3458 C CD2   . PHE B 2 81  ? 279.416 171.661 187.738 1.00 93.17  ? 84  PHE C CD2   1 
ATOM   3459 C CE1   . PHE B 2 81  ? 280.423 172.539 190.143 1.00 93.17  ? 84  PHE C CE1   1 
ATOM   3460 C CE2   . PHE B 2 81  ? 280.133 172.837 187.797 1.00 93.17  ? 84  PHE C CE2   1 
ATOM   3461 C CZ    . PHE B 2 81  ? 280.637 173.277 189.001 1.00 93.17  ? 84  PHE C CZ    1 
ATOM   3462 N N     . ASP B 2 82  ? 278.975 166.003 188.229 1.00 95.60  ? 85  ASP C N     1 
ATOM   3463 C CA    . ASP B 2 82  ? 278.173 164.863 187.799 1.00 95.60  ? 85  ASP C CA    1 
ATOM   3464 C C     . ASP B 2 82  ? 277.553 164.110 188.965 1.00 95.60  ? 85  ASP C C     1 
ATOM   3465 O O     . ASP B 2 82  ? 276.384 163.719 188.890 1.00 95.60  ? 85  ASP C O     1 
ATOM   3466 C CB    . ASP B 2 82  ? 279.021 163.900 186.967 1.00 95.60  ? 85  ASP C CB    1 
ATOM   3467 C CG    . ASP B 2 82  ? 280.185 163.319 187.748 1.00 95.60  ? 85  ASP C CG    1 
ATOM   3468 O OD1   . ASP B 2 82  ? 280.402 163.736 188.906 1.00 95.60  ? 85  ASP C OD1   1 
ATOM   3469 O OD2   . ASP B 2 82  ? 280.876 162.432 187.208 1.00 95.60  ? 85  ASP C OD2   1 
ATOM   3470 N N     . LYS B 2 83  ? 278.309 163.904 190.043 1.00 89.09  ? 86  LYS C N     1 
ATOM   3471 C CA    . LYS B 2 83  ? 277.862 163.077 191.156 1.00 89.09  ? 86  LYS C CA    1 
ATOM   3472 C C     . LYS B 2 83  ? 278.003 163.829 192.476 1.00 89.09  ? 86  LYS C C     1 
ATOM   3473 O O     . LYS B 2 83  ? 278.154 163.205 193.531 1.00 89.09  ? 86  LYS C O     1 
ATOM   3474 C CB    . LYS B 2 83  ? 278.650 161.764 191.186 1.00 89.09  ? 86  LYS C CB    1 
ATOM   3475 C CG    . LYS B 2 83  ? 278.065 160.658 192.044 1.00 89.09  ? 86  LYS C CG    1 
ATOM   3476 C CD    . LYS B 2 83  ? 279.005 159.465 192.108 1.00 89.09  ? 86  LYS C CD    1 
ATOM   3477 C CE    . LYS B 2 83  ? 279.073 158.726 190.788 1.00 89.09  ? 86  LYS C CE    1 
ATOM   3478 N NZ    . LYS B 2 83  ? 277.778 158.067 190.474 1.00 89.09  ? 86  LYS C NZ    1 
ATOM   3479 N N     . ILE B 2 84  ? 277.975 165.163 192.426 1.00 85.64  ? 87  ILE C N     1 
ATOM   3480 C CA    . ILE B 2 84  ? 278.148 165.971 193.625 1.00 85.64  ? 87  ILE C CA    1 
ATOM   3481 C C     . ILE B 2 84  ? 277.159 165.525 194.692 1.00 85.64  ? 87  ILE C C     1 
ATOM   3482 O O     . ILE B 2 84  ? 276.022 165.135 194.394 1.00 85.64  ? 87  ILE C O     1 
ATOM   3483 C CB    . ILE B 2 84  ? 277.998 167.464 193.279 1.00 85.64  ? 87  ILE C CB    1 
ATOM   3484 C CG1   . ILE B 2 84  ? 278.823 168.325 194.234 1.00 85.64  ? 87  ILE C CG1   1 
ATOM   3485 C CG2   . ILE B 2 84  ? 276.546 167.891 193.291 1.00 85.64  ? 87  ILE C CG2   1 
ATOM   3486 C CD1   . ILE B 2 84  ? 280.312 168.205 194.026 1.00 85.64  ? 87  ILE C CD1   1 
ATOM   3487 N N     . GLU B 2 85  ? 277.610 165.526 195.945 1.00 84.35  ? 88  GLU C N     1 
ATOM   3488 C CA    . GLU B 2 85  ? 276.807 165.044 197.059 1.00 84.35  ? 88  GLU C CA    1 
ATOM   3489 C C     . GLU B 2 85  ? 276.171 166.176 197.854 1.00 84.35  ? 88  GLU C C     1 
ATOM   3490 O O     . GLU B 2 85  ? 275.625 165.936 198.934 1.00 84.35  ? 88  GLU C O     1 
ATOM   3491 C CB    . GLU B 2 85  ? 277.652 164.156 197.972 1.00 84.35  ? 88  GLU C CB    1 
ATOM   3492 C CG    . GLU B 2 85  ? 278.986 164.753 198.372 1.00 84.35  ? 88  GLU C CG    1 
ATOM   3493 C CD    . GLU B 2 85  ? 280.018 163.690 198.696 1.00 84.35  ? 88  GLU C CD    1 
ATOM   3494 O OE1   . GLU B 2 85  ? 279.758 162.503 198.409 1.00 84.35  ? 88  GLU C OE1   1 
ATOM   3495 O OE2   . GLU B 2 85  ? 281.086 164.037 199.242 1.00 84.35  ? 88  GLU C OE2   1 
ATOM   3496 N N     . ASP B 2 86  ? 276.229 167.401 197.341 1.00 81.44  ? 89  ASP C N     1 
ATOM   3497 C CA    . ASP B 2 86  ? 275.533 168.541 197.935 1.00 81.44  ? 89  ASP C CA    1 
ATOM   3498 C C     . ASP B 2 86  ? 275.003 169.368 196.770 1.00 81.44  ? 89  ASP C C     1 
ATOM   3499 O O     . ASP B 2 86  ? 275.738 170.166 196.184 1.00 81.44  ? 89  ASP C O     1 
ATOM   3500 C CB    . ASP B 2 86  ? 276.449 169.359 198.835 1.00 81.44  ? 89  ASP C CB    1 
ATOM   3501 C CG    . ASP B 2 86  ? 275.686 170.325 199.715 1.00 81.44  ? 89  ASP C CG    1 
ATOM   3502 O OD1   . ASP B 2 86  ? 274.459 170.459 199.535 1.00 81.44  ? 89  ASP C OD1   1 
ATOM   3503 O OD2   . ASP B 2 86  ? 276.314 170.953 200.591 1.00 81.44  ? 89  ASP C OD2   1 
ATOM   3504 N N     . MET B 2 87  ? 273.728 169.172 196.442 1.00 81.04  ? 90  MET C N     1 
ATOM   3505 C CA    . MET B 2 87  ? 273.163 169.732 195.223 1.00 81.04  ? 90  MET C CA    1 
ATOM   3506 C C     . MET B 2 87  ? 273.093 171.251 195.235 1.00 81.04  ? 90  MET C C     1 
ATOM   3507 O O     . MET B 2 87  ? 272.854 171.847 194.181 1.00 81.04  ? 90  MET C O     1 
ATOM   3508 C CB    . MET B 2 87  ? 271.784 169.128 194.995 1.00 81.04  ? 90  MET C CB    1 
ATOM   3509 C CG    . MET B 2 87  ? 271.797 167.636 195.207 1.00 81.04  ? 90  MET C CG    1 
ATOM   3510 S SD    . MET B 2 87  ? 270.585 166.717 194.265 1.00 81.04  ? 90  MET C SD    1 
ATOM   3511 C CE    . MET B 2 87  ? 271.376 165.116 194.277 1.00 81.04  ? 90  MET C CE    1 
ATOM   3512 N N     . ALA B 2 88  ? 273.311 171.895 196.379 1.00 81.97  ? 91  ALA C N     1 
ATOM   3513 C CA    . ALA B 2 88  ? 273.436 173.346 196.373 1.00 81.97  ? 91  ALA C CA    1 
ATOM   3514 C C     . ALA B 2 88  ? 274.710 173.816 195.685 1.00 81.97  ? 91  ALA C C     1 
ATOM   3515 O O     . ALA B 2 88  ? 274.880 175.023 195.493 1.00 81.97  ? 91  ALA C O     1 
ATOM   3516 C CB    . ALA B 2 88  ? 273.392 173.887 197.802 1.00 81.97  ? 91  ALA C CB    1 
ATOM   3517 N N     . MET B 2 89  ? 275.599 172.897 195.312 1.00 85.65  ? 92  MET C N     1 
ATOM   3518 C CA    . MET B 2 89  ? 276.865 173.232 194.680 1.00 85.65  ? 92  MET C CA    1 
ATOM   3519 C C     . MET B 2 89  ? 276.832 173.101 193.165 1.00 85.65  ? 92  MET C C     1 
ATOM   3520 O O     . MET B 2 89  ? 277.803 173.487 192.507 1.00 85.65  ? 92  MET C O     1 
ATOM   3521 C CB    . MET B 2 89  ? 277.984 172.351 195.245 1.00 85.65  ? 92  MET C CB    1 
ATOM   3522 C CG    . MET B 2 89  ? 278.141 172.462 196.747 1.00 85.65  ? 92  MET C CG    1 
ATOM   3523 S SD    . MET B 2 89  ? 278.511 174.144 197.273 1.00 85.65  ? 92  MET C SD    1 
ATOM   3524 C CE    . MET B 2 89  ? 278.321 173.998 199.047 1.00 85.65  ? 92  MET C CE    1 
ATOM   3525 N N     . LEU B 2 90  ? 275.760 172.554 192.601 1.00 85.73  ? 93  LEU C N     1 
ATOM   3526 C CA    . LEU B 2 90  ? 275.587 172.579 191.159 1.00 85.73  ? 93  LEU C CA    1 
ATOM   3527 C C     . LEU B 2 90  ? 275.491 174.020 190.670 1.00 85.73  ? 93  LEU C C     1 
ATOM   3528 O O     . LEU B 2 90  ? 275.286 174.957 191.445 1.00 85.73  ? 93  LEU C O     1 
ATOM   3529 C CB    . LEU B 2 90  ? 274.333 171.809 190.751 1.00 85.73  ? 93  LEU C CB    1 
ATOM   3530 C CG    . LEU B 2 90  ? 274.207 170.353 191.186 1.00 85.73  ? 93  LEU C CG    1 
ATOM   3531 C CD1   . LEU B 2 90  ? 272.775 169.887 191.023 1.00 85.73  ? 93  LEU C CD1   1 
ATOM   3532 C CD2   . LEU B 2 90  ? 275.138 169.486 190.378 1.00 85.73  ? 93  LEU C CD2   1 
ATOM   3533 N N     . THR B 2 91  ? 275.651 174.197 189.361 1.00 89.64  ? 94  THR C N     1 
ATOM   3534 C CA    . THR B 2 91  ? 275.544 175.530 188.787 1.00 89.64  ? 94  THR C CA    1 
ATOM   3535 C C     . THR B 2 91  ? 274.181 175.799 188.165 1.00 89.64  ? 94  THR C C     1 
ATOM   3536 O O     . THR B 2 91  ? 273.698 176.934 188.226 1.00 89.64  ? 94  THR C O     1 
ATOM   3537 C CB    . THR B 2 91  ? 276.644 175.751 187.746 1.00 89.64  ? 94  THR C CB    1 
ATOM   3538 O OG1   . THR B 2 91  ? 276.418 176.991 187.068 1.00 89.64  ? 94  THR C OG1   1 
ATOM   3539 C CG2   . THR B 2 91  ? 276.671 174.621 186.740 1.00 89.64  ? 94  THR C CG2   1 
ATOM   3540 N N     . PHE B 2 92  ? 273.547 174.789 187.580 1.00 90.58  ? 95  PHE C N     1 
ATOM   3541 C CA    . PHE B 2 92  ? 272.236 174.931 186.954 1.00 90.58  ? 95  PHE C CA    1 
ATOM   3542 C C     . PHE B 2 92  ? 271.221 174.217 187.837 1.00 90.58  ? 95  PHE C C     1 
ATOM   3543 O O     . PHE B 2 92  ? 271.038 173.002 187.729 1.00 90.58  ? 95  PHE C O     1 
ATOM   3544 C CB    . PHE B 2 92  ? 272.242 174.366 185.538 1.00 90.58  ? 95  PHE C CB    1 
ATOM   3545 C CG    . PHE B 2 92  ? 273.176 175.080 184.609 1.00 90.58  ? 95  PHE C CG    1 
ATOM   3546 C CD1   . PHE B 2 92  ? 273.050 176.438 184.389 1.00 90.58  ? 95  PHE C CD1   1 
ATOM   3547 C CD2   . PHE B 2 92  ? 274.184 174.394 183.959 1.00 90.58  ? 95  PHE C CD2   1 
ATOM   3548 C CE1   . PHE B 2 92  ? 273.911 177.097 183.540 1.00 90.58  ? 95  PHE C CE1   1 
ATOM   3549 C CE2   . PHE B 2 92  ? 275.045 175.048 183.110 1.00 90.58  ? 95  PHE C CE2   1 
ATOM   3550 C CZ    . PHE B 2 92  ? 274.909 176.401 182.900 1.00 90.58  ? 95  PHE C CZ    1 
ATOM   3551 N N     . LEU B 2 93  ? 270.562 174.975 188.710 1.00 87.17  ? 96  LEU C N     1 
ATOM   3552 C CA    . LEU B 2 93  ? 269.615 174.412 189.669 1.00 87.17  ? 96  LEU C CA    1 
ATOM   3553 C C     . LEU B 2 93  ? 268.227 174.418 189.048 1.00 87.17  ? 96  LEU C C     1 
ATOM   3554 O O     . LEU B 2 93  ? 267.542 175.441 189.036 1.00 87.17  ? 96  LEU C O     1 
ATOM   3555 C CB    . LEU B 2 93  ? 269.633 175.190 190.980 1.00 87.17  ? 96  LEU C CB    1 
ATOM   3556 C CG    . LEU B 2 93  ? 270.696 174.831 192.018 1.00 87.17  ? 96  LEU C CG    1 
ATOM   3557 C CD1   . LEU B 2 93  ? 270.581 173.371 192.406 1.00 87.17  ? 96  LEU C CD1   1 
ATOM   3558 C CD2   . LEU B 2 93  ? 272.094 175.154 191.540 1.00 87.17  ? 96  LEU C CD2   1 
ATOM   3559 N N     . HIS B 2 94  ? 267.812 173.270 188.527 1.00 90.66  ? 97  HIS C N     1 
ATOM   3560 C CA    . HIS B 2 94  ? 266.454 173.075 188.047 1.00 90.66  ? 97  HIS C CA    1 
ATOM   3561 C C     . HIS B 2 94  ? 266.022 171.653 188.373 1.00 90.66  ? 97  HIS C C     1 
ATOM   3562 O O     . HIS B 2 94  ? 266.816 170.830 188.831 1.00 90.66  ? 97  HIS C O     1 
ATOM   3563 C CB    . HIS B 2 94  ? 266.341 173.390 186.549 1.00 90.66  ? 97  HIS C CB    1 
ATOM   3564 C CG    . HIS B 2 94  ? 267.399 172.743 185.708 1.00 90.66  ? 97  HIS C CG    1 
ATOM   3565 N ND1   . HIS B 2 94  ? 267.307 171.443 185.257 1.00 90.66  ? 97  HIS C ND1   1 
ATOM   3566 C CD2   . HIS B 2 94  ? 268.562 173.232 185.214 1.00 90.66  ? 97  HIS C CD2   1 
ATOM   3567 C CE1   . HIS B 2 94  ? 268.376 171.154 184.537 1.00 90.66  ? 97  HIS C CE1   1 
ATOM   3568 N NE2   . HIS B 2 94  ? 269.151 172.223 184.494 1.00 90.66  ? 97  HIS C NE2   1 
ATOM   3569 N N     . GLU B 2 95  ? 264.744 171.372 188.136 1.00 89.84  ? 98  GLU C N     1 
ATOM   3570 C CA    . GLU B 2 95  ? 264.170 170.097 188.565 1.00 89.84  ? 98  GLU C CA    1 
ATOM   3571 C C     . GLU B 2 95  ? 264.776 168.891 187.857 1.00 89.84  ? 98  GLU C C     1 
ATOM   3572 O O     . GLU B 2 95  ? 265.068 167.891 188.538 1.00 89.84  ? 98  GLU C O     1 
ATOM   3573 C CB    . GLU B 2 95  ? 262.650 170.144 188.390 1.00 89.84  ? 98  GLU C CB    1 
ATOM   3574 C CG    . GLU B 2 95  ? 262.029 171.444 188.867 1.00 89.84  ? 98  GLU C CG    1 
ATOM   3575 C CD    . GLU B 2 95  ? 260.517 171.422 188.823 1.00 89.84  ? 98  GLU C CD    1 
ATOM   3576 O OE1   . GLU B 2 95  ? 259.945 170.420 188.344 1.00 89.84  ? 98  GLU C OE1   1 
ATOM   3577 O OE2   . GLU B 2 95  ? 259.900 172.410 189.269 1.00 89.84  ? 98  GLU C OE2   1 
ATOM   3578 N N     . PRO B 2 96  ? 264.974 168.890 186.532 1.00 90.38  ? 99  PRO C N     1 
ATOM   3579 C CA    . PRO B 2 96  ? 265.631 167.728 185.914 1.00 90.38  ? 99  PRO C CA    1 
ATOM   3580 C C     . PRO B 2 96  ? 267.023 167.479 186.455 1.00 90.38  ? 99  PRO C C     1 
ATOM   3581 O O     . PRO B 2 96  ? 267.415 166.320 186.624 1.00 90.38  ? 99  PRO C O     1 
ATOM   3582 C CB    . PRO B 2 96  ? 265.661 168.096 184.426 1.00 90.38  ? 99  PRO C CB    1 
ATOM   3583 C CG    . PRO B 2 96  ? 264.585 169.075 184.258 1.00 90.38  ? 99  PRO C CG    1 
ATOM   3584 C CD    . PRO B 2 96  ? 264.562 169.872 185.514 1.00 90.38  ? 99  PRO C CD    1 
ATOM   3585 N N     . ALA B 2 97  ? 267.777 168.542 186.741 1.00 87.86  ? 100 ALA C N     1 
ATOM   3586 C CA    . ALA B 2 97  ? 269.133 168.380 187.254 1.00 87.86  ? 100 ALA C CA    1 
ATOM   3587 C C     . ALA B 2 97  ? 269.132 167.638 188.583 1.00 87.86  ? 100 ALA C C     1 
ATOM   3588 O O     . ALA B 2 97  ? 269.870 166.665 188.763 1.00 87.86  ? 100 ALA C O     1 
ATOM   3589 C CB    . ALA B 2 97  ? 269.805 169.745 187.399 1.00 87.86  ? 100 ALA C CB    1 
ATOM   3590 N N     . VAL B 2 98  ? 268.310 168.088 189.530 1.00 83.66  ? 101 VAL C N     1 
ATOM   3591 C CA    . VAL B 2 98  ? 268.244 167.442 190.836 1.00 83.66  ? 101 VAL C CA    1 
ATOM   3592 C C     . VAL B 2 98  ? 267.721 166.018 190.707 1.00 83.66  ? 101 VAL C C     1 
ATOM   3593 O O     . VAL B 2 98  ? 268.259 165.083 191.317 1.00 83.66  ? 101 VAL C O     1 
ATOM   3594 C CB    . VAL B 2 98  ? 267.377 168.283 191.786 1.00 83.66  ? 101 VAL C CB    1 
ATOM   3595 C CG1   . VAL B 2 98  ? 267.143 167.547 193.088 1.00 83.66  ? 101 VAL C CG1   1 
ATOM   3596 C CG2   . VAL B 2 98  ? 268.035 169.625 192.019 1.00 83.66  ? 101 VAL C CG2   1 
ATOM   3597 N N     . LEU B 2 99  ? 266.656 165.832 189.922 1.00 86.14  ? 102 LEU C N     1 
ATOM   3598 C CA    . LEU B 2 99  ? 266.105 164.495 189.721 1.00 86.14  ? 102 LEU C CA    1 
ATOM   3599 C C     . LEU B 2 99  ? 267.168 163.533 189.217 1.00 86.14  ? 102 LEU C C     1 
ATOM   3600 O O     . LEU B 2 99  ? 267.345 162.438 189.762 1.00 86.14  ? 102 LEU C O     1 
ATOM   3601 C CB    . LEU B 2 99  ? 264.941 164.550 188.736 1.00 86.14  ? 102 LEU C CB    1 
ATOM   3602 C CG    . LEU B 2 99  ? 264.406 163.183 188.312 1.00 86.14  ? 102 LEU C CG    1 
ATOM   3603 C CD1   . LEU B 2 99  ? 263.872 162.436 189.513 1.00 86.14  ? 102 LEU C CD1   1 
ATOM   3604 C CD2   . LEU B 2 99  ? 263.342 163.321 187.239 1.00 86.14  ? 102 LEU C CD2   1 
ATOM   3605 N N     . TYR B 2 100 ? 267.901 163.932 188.182 1.00 88.76  ? 103 TYR C N     1 
ATOM   3606 C CA    . TYR B 2 100 ? 268.862 163.028 187.577 1.00 88.76  ? 103 TYR C CA    1 
ATOM   3607 C C     . TYR B 2 100 ? 270.140 162.905 188.384 1.00 88.76  ? 103 TYR C C     1 
ATOM   3608 O O     . TYR B 2 100 ? 270.814 161.883 188.278 1.00 88.76  ? 103 TYR C O     1 
ATOM   3609 C CB    . TYR B 2 100 ? 269.161 163.467 186.147 1.00 88.76  ? 103 TYR C CB    1 
ATOM   3610 C CG    . TYR B 2 100 ? 268.253 162.783 185.157 1.00 88.76  ? 103 TYR C CG    1 
ATOM   3611 C CD1   . TYR B 2 100 ? 268.210 161.399 185.075 1.00 88.76  ? 103 TYR C CD1   1 
ATOM   3612 C CD2   . TYR B 2 100 ? 267.399 163.512 184.347 1.00 88.76  ? 103 TYR C CD2   1 
ATOM   3613 C CE1   . TYR B 2 100 ? 267.372 160.766 184.186 1.00 88.76  ? 103 TYR C CE1   1 
ATOM   3614 C CE2   . TYR B 2 100 ? 266.556 162.886 183.456 1.00 88.76  ? 103 TYR C CE2   1 
ATOM   3615 C CZ    . TYR B 2 100 ? 266.546 161.514 183.380 1.00 88.76  ? 103 TYR C CZ    1 
ATOM   3616 O OH    . TYR B 2 100 ? 265.706 160.884 182.494 1.00 88.76  ? 103 TYR C OH    1 
ATOM   3617 N N     . ASN B 2 101 ? 270.473 163.889 189.217 1.00 83.88  ? 104 ASN C N     1 
ATOM   3618 C CA    . ASN B 2 101 ? 271.574 163.700 190.153 1.00 83.88  ? 104 ASN C CA    1 
ATOM   3619 C C     . ASN B 2 101 ? 271.217 162.643 191.193 1.00 83.88  ? 104 ASN C C     1 
ATOM   3620 O O     . ASN B 2 101 ? 272.024 161.752 191.488 1.00 83.88  ? 104 ASN C O     1 
ATOM   3621 C CB    . ASN B 2 101 ? 271.933 165.033 190.809 1.00 83.88  ? 104 ASN C CB    1 
ATOM   3622 C CG    . ASN B 2 101 ? 273.295 165.013 191.466 1.00 83.88  ? 104 ASN C CG    1 
ATOM   3623 O OD1   . ASN B 2 101 ? 273.645 164.065 192.162 1.00 83.88  ? 104 ASN C OD1   1 
ATOM   3624 N ND2   . ASN B 2 101 ? 274.071 166.065 191.251 1.00 83.88  ? 104 ASN C ND2   1 
ATOM   3625 N N     . LEU B 2 102 ? 270.000 162.715 191.746 1.00 83.89  ? 105 LEU C N     1 
ATOM   3626 C CA    . LEU B 2 102 ? 269.523 161.640 192.616 1.00 83.89  ? 105 LEU C CA    1 
ATOM   3627 C C     . LEU B 2 102 ? 269.577 160.294 191.905 1.00 83.89  ? 105 LEU C C     1 
ATOM   3628 O O     . LEU B 2 102 ? 270.078 159.306 192.454 1.00 83.89  ? 105 LEU C O     1 
ATOM   3629 C CB    . LEU B 2 102 ? 268.093 161.907 193.094 1.00 83.89  ? 105 LEU C CB    1 
ATOM   3630 C CG    . LEU B 2 102 ? 267.767 162.653 194.392 1.00 83.89  ? 105 LEU C CG    1 
ATOM   3631 C CD1   . LEU B 2 102 ? 268.451 161.991 195.575 1.00 83.89  ? 105 LEU C CD1   1 
ATOM   3632 C CD2   . LEU B 2 102 ? 268.070 164.127 194.335 1.00 83.89  ? 105 LEU C CD2   1 
ATOM   3633 N N     . LYS B 2 103 ? 269.051 160.239 190.680 1.00 87.16  ? 106 LYS C N     1 
ATOM   3634 C CA    . LYS B 2 103 ? 268.984 158.975 189.952 1.00 87.16  ? 106 LYS C CA    1 
ATOM   3635 C C     . LYS B 2 103 ? 270.374 158.428 189.656 1.00 87.16  ? 106 LYS C C     1 
ATOM   3636 O O     . LYS B 2 103 ? 270.610 157.218 189.757 1.00 87.16  ? 106 LYS C O     1 
ATOM   3637 C CB    . LYS B 2 103 ? 268.193 159.165 188.659 1.00 87.16  ? 106 LYS C CB    1 
ATOM   3638 C CG    . LYS B 2 103 ? 267.864 157.882 187.926 1.00 87.16  ? 106 LYS C CG    1 
ATOM   3639 C CD    . LYS B 2 103 ? 266.909 158.151 186.777 1.00 87.16  ? 106 LYS C CD    1 
ATOM   3640 C CE    . LYS B 2 103 ? 266.390 156.857 186.182 1.00 87.16  ? 106 LYS C CE    1 
ATOM   3641 N NZ    . LYS B 2 103 ? 265.413 157.106 185.088 1.00 87.16  ? 106 LYS C NZ    1 
ATOM   3642 N N     . GLU B 2 104 ? 271.310 159.306 189.300 1.00 87.77  ? 107 GLU C N     1 
ATOM   3643 C CA    . GLU B 2 104 ? 272.655 158.873 188.955 1.00 87.77  ? 107 GLU C CA    1 
ATOM   3644 C C     . GLU B 2 104 ? 273.408 158.388 190.185 1.00 87.77  ? 107 GLU C C     1 
ATOM   3645 O O     . GLU B 2 104 ? 274.140 157.396 190.117 1.00 87.77  ? 107 GLU C O     1 
ATOM   3646 C CB    . GLU B 2 104 ? 273.401 160.017 188.274 1.00 87.77  ? 107 GLU C CB    1 
ATOM   3647 C CG    . GLU B 2 104 ? 274.747 159.642 187.704 1.00 87.77  ? 107 GLU C CG    1 
ATOM   3648 C CD    . GLU B 2 104 ? 275.881 159.919 188.663 1.00 87.77  ? 107 GLU C CD    1 
ATOM   3649 O OE1   . GLU B 2 104 ? 276.789 159.071 188.762 1.00 87.77  ? 107 GLU C OE1   1 
ATOM   3650 O OE2   . GLU B 2 104 ? 275.862 160.978 189.323 1.00 87.77  ? 107 GLU C OE2   1 
ATOM   3651 N N     . ARG B 2 105 ? 273.245 159.071 191.321 1.00 83.41  ? 108 ARG C N     1 
ATOM   3652 C CA    . ARG B 2 105 ? 273.877 158.580 192.539 1.00 83.41  ? 108 ARG C CA    1 
ATOM   3653 C C     . ARG B 2 105 ? 273.235 157.289 193.017 1.00 83.41  ? 108 ARG C C     1 
ATOM   3654 O O     . ARG B 2 105 ? 273.901 156.467 193.652 1.00 83.41  ? 108 ARG C O     1 
ATOM   3655 C CB    . ARG B 2 105 ? 273.816 159.634 193.639 1.00 83.41  ? 108 ARG C CB    1 
ATOM   3656 C CG    . ARG B 2 105 ? 274.824 160.746 193.476 1.00 83.41  ? 108 ARG C CG    1 
ATOM   3657 C CD    . ARG B 2 105 ? 274.792 161.683 194.656 1.00 83.41  ? 108 ARG C CD    1 
ATOM   3658 N NE    . ARG B 2 105 ? 275.313 161.043 195.856 1.00 83.41  ? 108 ARG C NE    1 
ATOM   3659 C CZ    . ARG B 2 105 ? 276.568 161.159 196.272 1.00 83.41  ? 108 ARG C CZ    1 
ATOM   3660 N NH1   . ARG B 2 105 ? 277.428 161.887 195.579 1.00 83.41  ? 108 ARG C NH1   1 
ATOM   3661 N NH2   . ARG B 2 105 ? 276.964 160.545 197.376 1.00 83.41  ? 108 ARG C NH2   1 
ATOM   3662 N N     . TYR B 2 106 ? 271.950 157.090 192.729 1.00 85.22  ? 109 TYR C N     1 
ATOM   3663 C CA    . TYR B 2 106 ? 271.300 155.851 193.129 1.00 85.22  ? 109 TYR C CA    1 
ATOM   3664 C C     . TYR B 2 106 ? 271.688 154.689 192.225 1.00 85.22  ? 109 TYR C C     1 
ATOM   3665 O O     . TYR B 2 106 ? 271.685 153.537 192.671 1.00 85.22  ? 109 TYR C O     1 
ATOM   3666 C CB    . TYR B 2 106 ? 269.784 156.036 193.134 1.00 85.22  ? 109 TYR C CB    1 
ATOM   3667 C CG    . TYR B 2 106 ? 269.032 154.868 193.717 1.00 85.22  ? 109 TYR C CG    1 
ATOM   3668 C CD1   . TYR B 2 106 ? 269.409 154.313 194.927 1.00 85.22  ? 109 TYR C CD1   1 
ATOM   3669 C CD2   . TYR B 2 106 ? 267.938 154.328 193.062 1.00 85.22  ? 109 TYR C CD2   1 
ATOM   3670 C CE1   . TYR B 2 106 ? 268.723 153.249 195.465 1.00 85.22  ? 109 TYR C CE1   1 
ATOM   3671 C CE2   . TYR B 2 106 ? 267.247 153.264 193.593 1.00 85.22  ? 109 TYR C CE2   1 
ATOM   3672 C CZ    . TYR B 2 106 ? 267.642 152.729 194.794 1.00 85.22  ? 109 TYR C CZ    1 
ATOM   3673 O OH    . TYR B 2 106 ? 266.953 151.668 195.326 1.00 85.22  ? 109 TYR C OH    1 
ATOM   3674 N N     . ALA B 2 107 ? 272.014 154.965 190.961 1.00 87.76  ? 110 ALA C N     1 
ATOM   3675 C CA    . ALA B 2 107 ? 272.473 153.910 190.063 1.00 87.76  ? 110 ALA C CA    1 
ATOM   3676 C C     . ALA B 2 107 ? 273.773 153.296 190.566 1.00 87.76  ? 110 ALA C C     1 
ATOM   3677 O O     . ALA B 2 107 ? 273.819 152.117 190.935 1.00 87.76  ? 110 ALA C O     1 
ATOM   3678 C CB    . ALA B 2 107 ? 272.644 154.467 188.649 1.00 87.76  ? 110 ALA C CB    1 
ATOM   3679 N N     . ALA B 2 108 ? 274.845 154.082 190.588 1.00 88.48  ? 111 ALA C N     1 
ATOM   3680 C CA    . ALA B 2 108 ? 276.095 153.668 191.222 1.00 88.48  ? 111 ALA C CA    1 
ATOM   3681 C C     . ALA B 2 108 ? 275.905 153.786 192.724 1.00 88.48  ? 111 ALA C C     1 
ATOM   3682 O O     . ALA B 2 108 ? 276.114 154.855 193.299 1.00 88.48  ? 111 ALA C O     1 
ATOM   3683 C CB    . ALA B 2 108 ? 277.255 154.530 190.739 1.00 88.48  ? 111 ALA C CB    1 
ATOM   3684 N N     . TRP B 2 109 ? 275.535 152.674 193.366 1.00 89.22  ? 112 TRP C N     1 
ATOM   3685 C CA    . TRP B 2 109 ? 274.813 152.706 194.635 1.00 89.22  ? 112 TRP C CA    1 
ATOM   3686 C C     . TRP B 2 109 ? 275.432 153.642 195.661 1.00 89.22  ? 112 TRP C C     1 
ATOM   3687 O O     . TRP B 2 109 ? 276.500 153.365 196.213 1.00 89.22  ? 112 TRP C O     1 
ATOM   3688 C CB    . TRP B 2 109 ? 274.728 151.297 195.220 1.00 89.22  ? 112 TRP C CB    1 
ATOM   3689 C CG    . TRP B 2 109 ? 274.036 150.335 194.324 1.00 89.22  ? 112 TRP C CG    1 
ATOM   3690 C CD1   . TRP B 2 109 ? 274.544 149.751 193.203 1.00 89.22  ? 112 TRP C CD1   1 
ATOM   3691 C CD2   . TRP B 2 109 ? 272.699 149.848 194.460 1.00 89.22  ? 112 TRP C CD2   1 
ATOM   3692 N NE1   . TRP B 2 109 ? 273.608 148.926 192.634 1.00 89.22  ? 112 TRP C NE1   1 
ATOM   3693 C CE2   . TRP B 2 109 ? 272.465 148.968 193.387 1.00 89.22  ? 112 TRP C CE2   1 
ATOM   3694 C CE3   . TRP B 2 109 ? 271.677 150.069 195.387 1.00 89.22  ? 112 TRP C CE3   1 
ATOM   3695 C CZ2   . TRP B 2 109 ? 271.254 148.309 193.215 1.00 89.22  ? 112 TRP C CZ2   1 
ATOM   3696 C CZ3   . TRP B 2 109 ? 270.475 149.414 195.214 1.00 89.22  ? 112 TRP C CZ3   1 
ATOM   3697 C CH2   . TRP B 2 109 ? 270.273 148.546 194.137 1.00 89.22  ? 112 TRP C CH2   1 
ATOM   3698 N N     . MET B 2 110 ? 274.727 154.741 195.933 1.00 84.45  ? 113 MET C N     1 
ATOM   3699 C CA    . MET B 2 110 ? 275.040 155.720 196.975 1.00 84.45  ? 113 MET C CA    1 
ATOM   3700 C C     . MET B 2 110 ? 273.689 156.335 197.340 1.00 84.45  ? 113 MET C C     1 
ATOM   3701 O O     . MET B 2 110 ? 273.226 157.271 196.686 1.00 84.45  ? 113 MET C O     1 
ATOM   3702 C CB    . MET B 2 110 ? 276.029 156.781 196.509 1.00 84.45  ? 113 MET C CB    1 
ATOM   3703 C CG    . MET B 2 110 ? 277.394 156.263 196.093 1.00 84.45  ? 113 MET C CG    1 
ATOM   3704 S SD    . MET B 2 110 ? 278.234 157.330 194.915 1.00 84.45  ? 113 MET C SD    1 
ATOM   3705 C CE    . MET B 2 110 ? 279.118 158.423 196.016 1.00 84.45  ? 113 MET C CE    1 
ATOM   3706 N N     . ILE B 2 111 ? 273.059 155.794 198.382 1.00 75.27  ? 114 ILE C N     1 
ATOM   3707 C CA    . ILE B 2 111 ? 271.653 156.105 198.619 1.00 75.27  ? 114 ILE C CA    1 
ATOM   3708 C C     . ILE B 2 111 ? 271.427 157.435 199.318 1.00 75.27  ? 114 ILE C C     1 
ATOM   3709 O O     . ILE B 2 111 ? 270.302 157.947 199.283 1.00 75.27  ? 114 ILE C O     1 
ATOM   3710 C CB    . ILE B 2 111 ? 270.991 154.962 199.406 1.00 75.27  ? 114 ILE C CB    1 
ATOM   3711 C CG1   . ILE B 2 111 ? 271.701 154.740 200.732 1.00 75.27  ? 114 ILE C CG1   1 
ATOM   3712 C CG2   . ILE B 2 111 ? 271.006 153.684 198.597 1.00 75.27  ? 114 ILE C CG2   1 
ATOM   3713 C CD1   . ILE B 2 111 ? 270.992 153.759 201.620 1.00 75.27  ? 114 ILE C CD1   1 
ATOM   3714 N N     . TYR B 2 112 ? 272.447 158.023 199.935 1.00 74.48  ? 115 TYR C N     1 
ATOM   3715 C CA    . TYR B 2 112 ? 272.288 159.272 200.666 1.00 74.48  ? 115 TYR C CA    1 
ATOM   3716 C C     . TYR B 2 112 ? 272.909 160.428 199.898 1.00 74.48  ? 115 TYR C C     1 
ATOM   3717 O O     . TYR B 2 112 ? 273.979 160.287 199.302 1.00 74.48  ? 115 TYR C O     1 
ATOM   3718 C CB    . TYR B 2 112 ? 272.926 159.199 202.049 1.00 74.48  ? 115 TYR C CB    1 
ATOM   3719 C CG    . TYR B 2 112 ? 272.469 158.038 202.880 1.00 74.48  ? 115 TYR C CG    1 
ATOM   3720 C CD1   . TYR B 2 112 ? 271.254 158.069 203.538 1.00 74.48  ? 115 TYR C CD1   1 
ATOM   3721 C CD2   . TYR B 2 112 ? 273.263 156.914 203.019 1.00 74.48  ? 115 TYR C CD2   1 
ATOM   3722 C CE1   . TYR B 2 112 ? 270.837 157.007 204.296 1.00 74.48  ? 115 TYR C CE1   1 
ATOM   3723 C CE2   . TYR B 2 112 ? 272.856 155.851 203.776 1.00 74.48  ? 115 TYR C CE2   1 
ATOM   3724 C CZ    . TYR B 2 112 ? 271.642 155.901 204.410 1.00 74.48  ? 115 TYR C CZ    1 
ATOM   3725 O OH    . TYR B 2 112 ? 271.235 154.835 205.165 1.00 74.48  ? 115 TYR C OH    1 
ATOM   3726 N N     . THR B 2 113 ? 272.233 161.573 199.927 1.00 72.83  ? 116 THR C N     1 
ATOM   3727 C CA    . THR B 2 113 ? 272.720 162.779 199.279 1.00 72.83  ? 116 THR C CA    1 
ATOM   3728 C C     . THR B 2 113 ? 272.168 163.989 200.013 1.00 72.83  ? 116 THR C C     1 
ATOM   3729 O O     . THR B 2 113 ? 270.987 164.022 200.365 1.00 72.83  ? 116 THR C O     1 
ATOM   3730 C CB    . THR B 2 113 ? 272.308 162.845 197.803 1.00 72.83  ? 116 THR C CB    1 
ATOM   3731 O OG1   . THR B 2 113 ? 272.466 161.559 197.191 1.00 72.83  ? 116 THR C OG1   1 
ATOM   3732 C CG2   . THR B 2 113 ? 273.163 163.855 197.066 1.00 72.83  ? 116 THR C CG2   1 
ATOM   3733 N N     . TYR B 2 114 ? 273.023 164.979 200.238 1.00 74.81  ? 117 TYR C N     1 
ATOM   3734 C CA    . TYR B 2 114 ? 272.597 166.241 200.820 1.00 74.81  ? 117 TYR C CA    1 
ATOM   3735 C C     . TYR B 2 114 ? 271.951 167.104 199.751 1.00 74.81  ? 117 TYR C C     1 
ATOM   3736 O O     . TYR B 2 114 ? 272.348 167.063 198.585 1.00 74.81  ? 117 TYR C O     1 
ATOM   3737 C CB    . TYR B 2 114 ? 273.781 166.997 201.417 1.00 74.81  ? 117 TYR C CB    1 
ATOM   3738 C CG    . TYR B 2 114 ? 274.391 166.350 202.627 1.00 74.81  ? 117 TYR C CG    1 
ATOM   3739 C CD1   . TYR B 2 114 ? 273.600 165.748 203.590 1.00 74.81  ? 117 TYR C CD1   1 
ATOM   3740 C CD2   . TYR B 2 114 ? 275.762 166.349 202.809 1.00 74.81  ? 117 TYR C CD2   1 
ATOM   3741 C CE1   . TYR B 2 114 ? 274.158 165.158 204.695 1.00 74.81  ? 117 TYR C CE1   1 
ATOM   3742 C CE2   . TYR B 2 114 ? 276.327 165.765 203.909 1.00 74.81  ? 117 TYR C CE2   1 
ATOM   3743 C CZ    . TYR B 2 114 ? 275.524 165.170 204.848 1.00 74.81  ? 117 TYR C CZ    1 
ATOM   3744 O OH    . TYR B 2 114 ? 276.096 164.587 205.947 1.00 74.81  ? 117 TYR C OH    1 
ATOM   3745 N N     . SER B 2 115 ? 270.951 167.883 200.150 1.00 71.42  ? 118 SER C N     1 
ATOM   3746 C CA    . SER B 2 115 ? 270.418 168.955 199.311 1.00 71.42  ? 118 SER C CA    1 
ATOM   3747 C C     . SER B 2 115 ? 270.312 170.202 200.182 1.00 71.42  ? 118 SER C C     1 
ATOM   3748 O O     . SER B 2 115 ? 269.242 170.527 200.699 1.00 71.42  ? 118 SER C O     1 
ATOM   3749 C CB    . SER B 2 115 ? 269.081 168.564 198.707 1.00 71.42  ? 118 SER C CB    1 
ATOM   3750 O OG    . SER B 2 115 ? 268.354 169.712 198.313 1.00 71.42  ? 118 SER C OG    1 
ATOM   3751 N N     . GLY B 2 116 ? 271.427 170.907 200.334 1.00 71.19  ? 119 GLY C N     1 
ATOM   3752 C CA    . GLY B 2 116 ? 271.444 172.133 201.105 1.00 71.19  ? 119 GLY C CA    1 
ATOM   3753 C C     . GLY B 2 116 ? 271.453 171.900 202.601 1.00 71.19  ? 119 GLY C C     1 
ATOM   3754 O O     . GLY B 2 116 ? 272.483 172.072 203.257 1.00 71.19  ? 119 GLY C O     1 
ATOM   3755 N N     . LEU B 2 117 ? 270.307 171.501 203.149 1.00 67.88  ? 120 LEU C N     1 
ATOM   3756 C CA    . LEU B 2 117 ? 270.189 171.210 204.573 1.00 67.88  ? 120 LEU C CA    1 
ATOM   3757 C C     . LEU B 2 117 ? 269.633 169.811 204.784 1.00 67.88  ? 120 LEU C C     1 
ATOM   3758 O O     . LEU B 2 117 ? 269.897 169.180 205.811 1.00 67.88  ? 120 LEU C O     1 
ATOM   3759 C CB    . LEU B 2 117 ? 269.294 172.233 205.277 1.00 67.88  ? 120 LEU C CB    1 
ATOM   3760 C CG    . LEU B 2 117 ? 269.907 173.526 205.821 1.00 67.88  ? 120 LEU C CG    1 
ATOM   3761 C CD1   . LEU B 2 117 ? 270.935 173.214 206.894 1.00 67.88  ? 120 LEU C CD1   1 
ATOM   3762 C CD2   . LEU B 2 117 ? 270.518 174.380 204.722 1.00 67.88  ? 120 LEU C CD2   1 
ATOM   3763 N N     . PHE B 2 118 ? 268.857 169.324 203.820 1.00 66.29  ? 121 PHE C N     1 
ATOM   3764 C CA    . PHE B 2 118 ? 268.262 168.005 203.937 1.00 66.29  ? 121 PHE C CA    1 
ATOM   3765 C C     . PHE B 2 118 ? 269.325 166.924 203.796 1.00 66.29  ? 121 PHE C C     1 
ATOM   3766 O O     . PHE B 2 118 ? 270.457 167.169 203.375 1.00 66.29  ? 121 PHE C O     1 
ATOM   3767 C CB    . PHE B 2 118 ? 267.188 167.795 202.873 1.00 66.29  ? 121 PHE C CB    1 
ATOM   3768 C CG    . PHE B 2 118 ? 266.094 168.809 202.904 1.00 66.29  ? 121 PHE C CG    1 
ATOM   3769 C CD1   . PHE B 2 118 ? 265.026 168.665 203.763 1.00 66.29  ? 121 PHE C CD1   1 
ATOM   3770 C CD2   . PHE B 2 118 ? 266.120 169.893 202.054 1.00 66.29  ? 121 PHE C CD2   1 
ATOM   3771 C CE1   . PHE B 2 118 ? 264.015 169.590 203.789 1.00 66.29  ? 121 PHE C CE1   1 
ATOM   3772 C CE2   . PHE B 2 118 ? 265.110 170.818 202.074 1.00 66.29  ? 121 PHE C CE2   1 
ATOM   3773 C CZ    . PHE B 2 118 ? 264.056 170.666 202.944 1.00 66.29  ? 121 PHE C CZ    1 
ATOM   3774 N N     . CYS B 2 119 ? 268.938 165.702 204.152 1.00 66.13  ? 122 CYS C N     1 
ATOM   3775 C CA    . CYS B 2 119 ? 269.757 164.515 203.935 1.00 66.13  ? 122 CYS C CA    1 
ATOM   3776 C C     . CYS B 2 119 ? 268.849 163.511 203.238 1.00 66.13  ? 122 CYS C C     1 
ATOM   3777 O O     . CYS B 2 119 ? 268.204 162.688 203.890 1.00 66.13  ? 122 CYS C O     1 
ATOM   3778 C CB    . CYS B 2 119 ? 270.322 163.974 205.238 1.00 66.13  ? 122 CYS C CB    1 
ATOM   3779 S SG    . CYS B 2 119 ? 271.075 162.341 205.092 1.00 66.13  ? 122 CYS C SG    1 
ATOM   3780 N N     . VAL B 2 120 ? 268.801 163.585 201.911 1.00 66.65  ? 123 VAL C N     1 
ATOM   3781 C CA    . VAL B 2 120 ? 267.882 162.761 201.135 1.00 66.65  ? 123 VAL C CA    1 
ATOM   3782 C C     . VAL B 2 120 ? 268.335 161.309 201.188 1.00 66.65  ? 123 VAL C C     1 
ATOM   3783 O O     . VAL B 2 120 ? 269.486 160.989 200.877 1.00 66.65  ? 123 VAL C O     1 
ATOM   3784 C CB    . VAL B 2 120 ? 267.789 163.262 199.691 1.00 66.65  ? 123 VAL C CB    1 
ATOM   3785 C CG1   . VAL B 2 120 ? 266.832 162.404 198.901 1.00 66.65  ? 123 VAL C CG1   1 
ATOM   3786 C CG2   . VAL B 2 120 ? 267.347 164.708 199.667 1.00 66.65  ? 123 VAL C CG2   1 
ATOM   3787 N N     . THR B 2 121 ? 267.427 160.424 201.580 1.00 70.85  ? 124 THR C N     1 
ATOM   3788 C CA    . THR B 2 121 ? 267.675 158.993 201.640 1.00 70.85  ? 124 THR C CA    1 
ATOM   3789 C C     . THR B 2 121 ? 266.793 158.294 200.618 1.00 70.85  ? 124 THR C C     1 
ATOM   3790 O O     . THR B 2 121 ? 265.643 158.687 200.410 1.00 70.85  ? 124 THR C O     1 
ATOM   3791 C CB    . THR B 2 121 ? 267.383 158.450 203.042 1.00 70.85  ? 124 THR C CB    1 
ATOM   3792 O OG1   . THR B 2 121 ? 268.257 159.073 203.990 1.00 70.85  ? 124 THR C OG1   1 
ATOM   3793 C CG2   . THR B 2 121 ? 267.572 156.943 203.095 1.00 70.85  ? 124 THR C CG2   1 
ATOM   3794 N N     . VAL B 2 122 ? 267.329 157.263 199.974 1.00 74.90  ? 125 VAL C N     1 
ATOM   3795 C CA    . VAL B 2 122 ? 266.582 156.469 199.008 1.00 74.90  ? 125 VAL C CA    1 
ATOM   3796 C C     . VAL B 2 122 ? 266.468 155.051 199.545 1.00 74.90  ? 125 VAL C C     1 
ATOM   3797 O O     . VAL B 2 122 ? 267.472 154.453 199.944 1.00 74.90  ? 125 VAL C O     1 
ATOM   3798 C CB    . VAL B 2 122 ? 267.247 156.480 197.620 1.00 74.90  ? 125 VAL C CB    1 
ATOM   3799 C CG1   . VAL B 2 122 ? 266.289 155.956 196.578 1.00 74.90  ? 125 VAL C CG1   1 
ATOM   3800 C CG2   . VAL B 2 122 ? 267.697 157.881 197.261 1.00 74.90  ? 125 VAL C CG2   1 
ATOM   3801 N N     . ASN B 2 123 ? 265.254 154.527 199.567 1.00 81.43  ? 126 ASN C N     1 
ATOM   3802 C CA    . ASN B 2 123 ? 265.032 153.156 200.004 1.00 81.43  ? 126 ASN C CA    1 
ATOM   3803 C C     . ASN B 2 123 ? 265.710 152.217 199.018 1.00 81.43  ? 126 ASN C C     1 
ATOM   3804 O O     . ASN B 2 123 ? 265.344 152.207 197.838 1.00 81.43  ? 126 ASN C O     1 
ATOM   3805 C CB    . ASN B 2 123 ? 263.538 152.867 200.090 1.00 81.43  ? 126 ASN C CB    1 
ATOM   3806 C CG    . ASN B 2 123 ? 263.231 151.529 200.737 1.00 81.43  ? 126 ASN C CG    1 
ATOM   3807 O OD1   . ASN B 2 123 ? 263.997 150.574 200.624 1.00 81.43  ? 126 ASN C OD1   1 
ATOM   3808 N ND2   . ASN B 2 123 ? 262.096 151.455 201.419 1.00 81.43  ? 126 ASN C ND2   1 
ATOM   3809 N N     . PRO B 2 124 ? 266.690 151.428 199.439 1.00 84.11  ? 127 PRO C N     1 
ATOM   3810 C CA    . PRO B 2 124 ? 267.441 150.619 198.474 1.00 84.11  ? 127 PRO C CA    1 
ATOM   3811 C C     . PRO B 2 124 ? 266.804 149.272 198.179 1.00 84.11  ? 127 PRO C C     1 
ATOM   3812 O O     . PRO B 2 124 ? 267.082 148.675 197.136 1.00 84.11  ? 127 PRO C O     1 
ATOM   3813 C CB    . PRO B 2 124 ? 268.798 150.453 199.163 1.00 84.11  ? 127 PRO C CB    1 
ATOM   3814 C CG    . PRO B 2 124 ? 268.447 150.416 200.612 1.00 84.11  ? 127 PRO C CG    1 
ATOM   3815 C CD    . PRO B 2 124 ? 267.251 151.325 200.796 1.00 84.11  ? 127 PRO C CD    1 
ATOM   3816 N N     . TYR B 2 125 ? 265.969 148.777 199.089 1.00 86.28  ? 128 TYR C N     1 
ATOM   3817 C CA    . TYR B 2 125 ? 265.368 147.447 199.024 1.00 86.28  ? 128 TYR C CA    1 
ATOM   3818 C C     . TYR B 2 125 ? 266.408 146.335 198.985 1.00 86.28  ? 128 TYR C C     1 
ATOM   3819 O O     . TYR B 2 125 ? 266.053 145.171 198.772 1.00 86.28  ? 128 TYR C O     1 
ATOM   3820 C CB    . TYR B 2 125 ? 264.423 147.298 197.823 1.00 86.28  ? 128 TYR C CB    1 
ATOM   3821 C CG    . TYR B 2 125 ? 263.382 148.381 197.703 1.00 86.28  ? 128 TYR C CG    1 
ATOM   3822 C CD1   . TYR B 2 125 ? 262.384 148.518 198.655 1.00 86.28  ? 128 TYR C CD1   1 
ATOM   3823 C CD2   . TYR B 2 125 ? 263.386 149.257 196.628 1.00 86.28  ? 128 TYR C CD2   1 
ATOM   3824 C CE1   . TYR B 2 125 ? 261.430 149.503 198.547 1.00 86.28  ? 128 TYR C CE1   1 
ATOM   3825 C CE2   . TYR B 2 125 ? 262.434 150.244 196.512 1.00 86.28  ? 128 TYR C CE2   1 
ATOM   3826 C CZ    . TYR B 2 125 ? 261.459 150.362 197.474 1.00 86.28  ? 128 TYR C CZ    1 
ATOM   3827 O OH    . TYR B 2 125 ? 260.506 151.344 197.362 1.00 86.28  ? 128 TYR C OH    1 
ATOM   3828 N N     . LYS B 2 126 ? 267.681 146.660 199.184 1.00 89.52  ? 129 LYS C N     1 
ATOM   3829 C CA    . LYS B 2 126 ? 268.766 145.694 199.116 1.00 89.52  ? 129 LYS C CA    1 
ATOM   3830 C C     . LYS B 2 126 ? 269.688 145.932 200.297 1.00 89.52  ? 129 LYS C C     1 
ATOM   3831 O O     . LYS B 2 126 ? 270.067 147.075 200.567 1.00 89.52  ? 129 LYS C O     1 
ATOM   3832 C CB    . LYS B 2 126 ? 269.533 145.814 197.794 1.00 89.52  ? 129 LYS C CB    1 
ATOM   3833 C CG    . LYS B 2 126 ? 270.629 144.777 197.605 1.00 89.52  ? 129 LYS C CG    1 
ATOM   3834 C CD    . LYS B 2 126 ? 271.189 144.811 196.187 1.00 89.52  ? 129 LYS C CD    1 
ATOM   3835 C CE    . LYS B 2 126 ? 272.098 146.004 195.954 1.00 89.52  ? 129 LYS C CE    1 
ATOM   3836 N NZ    . LYS B 2 126 ? 273.391 145.858 196.675 1.00 89.52  ? 129 LYS C NZ    1 
ATOM   3837 N N     . TRP B 2 127 ? 270.030 144.861 201.008 1.00 94.38  ? 130 TRP C N     1 
ATOM   3838 C CA    . TRP B 2 127 ? 270.879 144.988 202.185 1.00 94.38  ? 130 TRP C CA    1 
ATOM   3839 C C     . TRP B 2 127 ? 272.236 145.560 201.802 1.00 94.38  ? 130 TRP C C     1 
ATOM   3840 O O     . TRP B 2 127 ? 272.919 145.036 200.918 1.00 94.38  ? 130 TRP C O     1 
ATOM   3841 C CB    . TRP B 2 127 ? 271.055 143.631 202.865 1.00 94.38  ? 130 TRP C CB    1 
ATOM   3842 C CG    . TRP B 2 127 ? 271.835 143.709 204.144 1.00 94.38  ? 130 TRP C CG    1 
ATOM   3843 C CD1   . TRP B 2 127 ? 271.330 143.833 205.404 1.00 94.38  ? 130 TRP C CD1   1 
ATOM   3844 C CD2   . TRP B 2 127 ? 273.262 143.677 204.286 1.00 94.38  ? 130 TRP C CD2   1 
ATOM   3845 N NE1   . TRP B 2 127 ? 272.349 143.877 206.321 1.00 94.38  ? 130 TRP C NE1   1 
ATOM   3846 C CE2   . TRP B 2 127 ? 273.545 143.784 205.660 1.00 94.38  ? 130 TRP C CE2   1 
ATOM   3847 C CE3   . TRP B 2 127 ? 274.325 143.568 203.385 1.00 94.38  ? 130 TRP C CE3   1 
ATOM   3848 C CZ2   . TRP B 2 127 ? 274.847 143.784 206.154 1.00 94.38  ? 130 TRP C CZ2   1 
ATOM   3849 C CZ3   . TRP B 2 127 ? 275.614 143.572 203.878 1.00 94.38  ? 130 TRP C CZ3   1 
ATOM   3850 C CH2   . TRP B 2 127 ? 275.864 143.677 205.249 1.00 94.38  ? 130 TRP C CH2   1 
ATOM   3851 N N     . LEU B 2 128 ? 272.628 146.636 202.481 1.00 91.55  ? 131 LEU C N     1 
ATOM   3852 C CA    . LEU B 2 128 ? 273.908 147.276 202.257 1.00 91.55  ? 131 LEU C CA    1 
ATOM   3853 C C     . LEU B 2 128 ? 274.590 147.434 203.606 1.00 91.55  ? 131 LEU C C     1 
ATOM   3854 O O     . LEU B 2 128 ? 273.927 147.763 204.599 1.00 91.55  ? 131 LEU C O     1 
ATOM   3855 C CB    . LEU B 2 128 ? 273.764 148.651 201.594 1.00 91.55  ? 131 LEU C CB    1 
ATOM   3856 C CG    . LEU B 2 128 ? 272.821 148.778 200.401 1.00 91.55  ? 131 LEU C CG    1 
ATOM   3857 C CD1   . LEU B 2 128 ? 272.754 150.220 199.937 1.00 91.55  ? 131 LEU C CD1   1 
ATOM   3858 C CD2   . LEU B 2 128 ? 273.271 147.877 199.275 1.00 91.55  ? 131 LEU C CD2   1 
ATOM   3859 N N     . PRO B 2 129 ? 275.899 147.225 203.674 1.00 93.46  ? 132 PRO C N     1 
ATOM   3860 C CA    . PRO B 2 129 ? 276.637 147.395 204.930 1.00 93.46  ? 132 PRO C CA    1 
ATOM   3861 C C     . PRO B 2 129 ? 276.956 148.859 205.216 1.00 93.46  ? 132 PRO C C     1 
ATOM   3862 O O     . PRO B 2 129 ? 278.077 149.210 205.596 1.00 93.46  ? 132 PRO C O     1 
ATOM   3863 C CB    . PRO B 2 129 ? 277.903 146.574 204.687 1.00 93.46  ? 132 PRO C CB    1 
ATOM   3864 C CG    . PRO B 2 129 ? 278.153 146.770 203.234 1.00 93.46  ? 132 PRO C CG    1 
ATOM   3865 C CD    . PRO B 2 129 ? 276.787 146.794 202.581 1.00 93.46  ? 132 PRO C CD    1 
ATOM   3866 N N     . VAL B 2 130 ? 275.962 149.730 205.035 1.00 87.91  ? 133 VAL C N     1 
ATOM   3867 C CA    . VAL B 2 130 ? 276.166 151.148 205.280 1.00 87.91  ? 133 VAL C CA    1 
ATOM   3868 C C     . VAL B 2 130 ? 275.866 151.491 206.735 1.00 87.91  ? 133 VAL C C     1 
ATOM   3869 O O     . VAL B 2 130 ? 276.019 152.647 207.146 1.00 87.91  ? 133 VAL C O     1 
ATOM   3870 C CB    . VAL B 2 130 ? 275.316 151.965 204.285 1.00 87.91  ? 133 VAL C CB    1 
ATOM   3871 C CG1   . VAL B 2 130 ? 273.843 151.889 204.639 1.00 87.91  ? 133 VAL C CG1   1 
ATOM   3872 C CG2   . VAL B 2 130 ? 275.804 153.400 204.175 1.00 87.91  ? 133 VAL C CG2   1 
ATOM   3873 N N     . TYR B 2 131 ? 275.421 150.513 207.523 1.00 88.24  ? 134 TYR C N     1 
ATOM   3874 C CA    . TYR B 2 131 ? 275.257 150.640 208.967 1.00 88.24  ? 134 TYR C CA    1 
ATOM   3875 C C     . TYR B 2 131 ? 276.081 149.616 209.729 1.00 88.24  ? 134 TYR C C     1 
ATOM   3876 O O     . TYR B 2 131 ? 276.092 149.628 210.965 1.00 88.24  ? 134 TYR C O     1 
ATOM   3877 C CB    . TYR B 2 131 ? 273.779 150.461 209.339 1.00 88.24  ? 134 TYR C CB    1 
ATOM   3878 C CG    . TYR B 2 131 ? 272.854 151.481 208.735 1.00 88.24  ? 134 TYR C CG    1 
ATOM   3879 C CD1   . TYR B 2 131 ? 272.685 152.725 209.317 1.00 88.24  ? 134 TYR C CD1   1 
ATOM   3880 C CD2   . TYR B 2 131 ? 272.145 151.195 207.577 1.00 88.24  ? 134 TYR C CD2   1 
ATOM   3881 C CE1   . TYR B 2 131 ? 271.840 153.661 208.768 1.00 88.24  ? 134 TYR C CE1   1 
ATOM   3882 C CE2   . TYR B 2 131 ? 271.294 152.121 207.015 1.00 88.24  ? 134 TYR C CE2   1 
ATOM   3883 C CZ    . TYR B 2 131 ? 271.144 153.356 207.621 1.00 88.24  ? 134 TYR C CZ    1 
ATOM   3884 O OH    . TYR B 2 131 ? 270.298 154.290 207.075 1.00 88.24  ? 134 TYR C OH    1 
ATOM   3885 N N     . ASN B 2 132 ? 276.771 148.734 209.008 1.00 99.01  ? 135 ASN C N     1 
ATOM   3886 C CA    . ASN B 2 132 ? 277.136 147.373 209.436 1.00 99.01  ? 135 ASN C CA    1 
ATOM   3887 C C     . ASN B 2 132 ? 277.770 147.369 210.829 1.00 99.01  ? 135 ASN C C     1 
ATOM   3888 O O     . ASN B 2 132 ? 277.123 146.920 211.785 1.00 99.01  ? 135 ASN C O     1 
ATOM   3889 C CB    . ASN B 2 132 ? 277.997 146.800 208.320 1.00 99.01  ? 135 ASN C CB    1 
ATOM   3890 C CG    . ASN B 2 132 ? 278.712 145.529 208.722 1.00 99.01  ? 135 ASN C CG    1 
ATOM   3891 O OD1   . ASN B 2 132 ? 278.183 144.713 209.478 1.00 99.01  ? 135 ASN C OD1   1 
ATOM   3892 N ND2   . ASN B 2 132 ? 279.929 145.357 208.218 1.00 99.01  ? 135 ASN C ND2   1 
ATOM   3893 N N     . ALA B 2 133 ? 278.997 147.841 210.993 1.00 98.59  ? 136 ALA C N     1 
ATOM   3894 C CA    . ALA B 2 133 ? 279.733 147.695 212.242 1.00 98.59  ? 136 ALA C CA    1 
ATOM   3895 C C     . ALA B 2 133 ? 279.996 149.083 212.832 1.00 98.59  ? 136 ALA C C     1 
ATOM   3896 O O     . ALA B 2 133 ? 279.453 150.055 212.298 1.00 98.59  ? 136 ALA C O     1 
ATOM   3897 C CB    . ALA B 2 133 ? 280.977 146.839 211.999 1.00 98.59  ? 136 ALA C CB    1 
ATOM   3898 N N     . GLU B 2 134 ? 280.793 149.222 213.892 1.00 98.62  ? 137 GLU C N     1 
ATOM   3899 C CA    . GLU B 2 134 ? 281.334 150.511 214.298 1.00 98.62  ? 137 GLU C CA    1 
ATOM   3900 C C     . GLU B 2 134 ? 282.273 151.087 213.242 1.00 98.62  ? 137 GLU C C     1 
ATOM   3901 O O     . GLU B 2 134 ? 282.556 152.289 213.266 1.00 98.62  ? 137 GLU C O     1 
ATOM   3902 C CB    . GLU B 2 134 ? 282.050 150.341 215.649 1.00 98.62  ? 137 GLU C CB    1 
ATOM   3903 C CG    . GLU B 2 134 ? 282.968 151.472 216.126 1.00 98.62  ? 137 GLU C CG    1 
ATOM   3904 C CD    . GLU B 2 134 ? 282.299 152.834 216.132 1.00 98.62  ? 137 GLU C CD    1 
ATOM   3905 O OE1   . GLU B 2 134 ? 281.267 152.983 216.817 1.00 98.62  ? 137 GLU C OE1   1 
ATOM   3906 O OE2   . GLU B 2 134 ? 282.816 153.762 215.473 1.00 98.62  ? 137 GLU C OE2   1 
ATOM   3907 N N     . VAL B 2 135 ? 282.719 150.270 212.285 1.00 98.04  ? 138 VAL C N     1 
ATOM   3908 C CA    . VAL B 2 135 ? 283.559 150.775 211.205 1.00 98.04  ? 138 VAL C CA    1 
ATOM   3909 C C     . VAL B 2 135 ? 282.828 151.866 210.432 1.00 98.04  ? 138 VAL C C     1 
ATOM   3910 O O     . VAL B 2 135 ? 283.428 152.863 210.014 1.00 98.04  ? 138 VAL C O     1 
ATOM   3911 C CB    . VAL B 2 135 ? 284.008 149.622 210.288 1.00 98.04  ? 138 VAL C CB    1 
ATOM   3912 C CG1   . VAL B 2 135 ? 282.810 148.876 209.722 1.00 98.04  ? 138 VAL C CG1   1 
ATOM   3913 C CG2   . VAL B 2 135 ? 284.901 150.138 209.173 1.00 98.04  ? 138 VAL C CG2   1 
ATOM   3914 N N     . VAL B 2 136 ? 281.514 151.703 210.247 1.00 93.73  ? 139 VAL C N     1 
ATOM   3915 C CA    . VAL B 2 136 ? 280.706 152.748 209.628 1.00 93.73  ? 139 VAL C CA    1 
ATOM   3916 C C     . VAL B 2 136 ? 280.087 153.670 210.666 1.00 93.73  ? 139 VAL C C     1 
ATOM   3917 O O     . VAL B 2 136 ? 279.630 154.769 210.316 1.00 93.73  ? 139 VAL C O     1 
ATOM   3918 C CB    . VAL B 2 136 ? 279.604 152.137 208.742 1.00 93.73  ? 139 VAL C CB    1 
ATOM   3919 C CG1   . VAL B 2 136 ? 279.025 153.183 207.807 1.00 93.73  ? 139 VAL C CG1   1 
ATOM   3920 C CG2   . VAL B 2 136 ? 280.150 150.959 207.963 1.00 93.73  ? 139 VAL C CG2   1 
ATOM   3921 N N     . ALA B 2 137 ? 280.075 153.273 211.939 1.00 92.98  ? 140 ALA C N     1 
ATOM   3922 C CA    . ALA B 2 137 ? 279.699 154.163 213.025 1.00 92.98  ? 140 ALA C CA    1 
ATOM   3923 C C     . ALA B 2 137 ? 280.871 155.021 213.476 1.00 92.98  ? 140 ALA C C     1 
ATOM   3924 O O     . ALA B 2 137 ? 280.813 155.636 214.545 1.00 92.98  ? 140 ALA C O     1 
ATOM   3925 C CB    . ALA B 2 137 ? 279.135 153.368 214.202 1.00 92.98  ? 140 ALA C CB    1 
ATOM   3926 N N     . ALA B 2 138 ? 281.937 155.059 212.683 1.00 90.17  ? 141 ALA C N     1 
ATOM   3927 C CA    . ALA B 2 138 ? 283.069 155.950 212.921 1.00 90.17  ? 141 ALA C CA    1 
ATOM   3928 C C     . ALA B 2 138 ? 282.815 157.327 212.319 1.00 90.17  ? 141 ALA C C     1 
ATOM   3929 O O     . ALA B 2 138 ? 283.632 157.883 211.587 1.00 90.17  ? 141 ALA C O     1 
ATOM   3930 C CB    . ALA B 2 138 ? 284.344 155.332 212.361 1.00 90.17  ? 141 ALA C CB    1 
ATOM   3931 N N     . TYR B 2 139 ? 281.644 157.875 212.632 1.00 85.73  ? 142 TYR C N     1 
ATOM   3932 C CA    . TYR B 2 139 ? 281.309 159.263 212.354 1.00 85.73  ? 142 TYR C CA    1 
ATOM   3933 C C     . TYR B 2 139 ? 281.467 160.126 213.596 1.00 85.73  ? 142 TYR C C     1 
ATOM   3934 O O     . TYR B 2 139 ? 280.988 161.264 213.617 1.00 85.73  ? 142 TYR C O     1 
ATOM   3935 C CB    . TYR B 2 139 ? 279.877 159.369 211.824 1.00 85.73  ? 142 TYR C CB    1 
ATOM   3936 C CG    . TYR B 2 139 ? 279.727 159.098 210.346 1.00 85.73  ? 142 TYR C CG    1 
ATOM   3937 C CD1   . TYR B 2 139 ? 279.706 160.136 209.430 1.00 85.73  ? 142 TYR C CD1   1 
ATOM   3938 C CD2   . TYR B 2 139 ? 279.599 157.805 209.868 1.00 85.73  ? 142 TYR C CD2   1 
ATOM   3939 C CE1   . TYR B 2 139 ? 279.563 159.891 208.082 1.00 85.73  ? 142 TYR C CE1   1 
ATOM   3940 C CE2   . TYR B 2 139 ? 279.458 157.553 208.521 1.00 85.73  ? 142 TYR C CE2   1 
ATOM   3941 C CZ    . TYR B 2 139 ? 279.443 158.602 207.635 1.00 85.73  ? 142 TYR C CZ    1 
ATOM   3942 O OH    . TYR B 2 139 ? 279.302 158.361 206.293 1.00 85.73  ? 142 TYR C OH    1 
ATOM   3943 N N     . ARG B 2 140 ? 282.135 159.609 214.628 1.00 87.21  ? 143 ARG C N     1 
ATOM   3944 C CA    . ARG B 2 140 ? 282.162 160.225 215.952 1.00 87.21  ? 143 ARG C CA    1 
ATOM   3945 C C     . ARG B 2 140 ? 283.072 161.447 215.919 1.00 87.21  ? 143 ARG C C     1 
ATOM   3946 O O     . ARG B 2 140 ? 284.267 161.387 216.212 1.00 87.21  ? 143 ARG C O     1 
ATOM   3947 C CB    . ARG B 2 140 ? 282.624 159.220 216.999 1.00 87.21  ? 143 ARG C CB    1 
ATOM   3948 C CG    . ARG B 2 140 ? 281.505 158.430 217.658 1.00 87.21  ? 143 ARG C CG    1 
ATOM   3949 C CD    . ARG B 2 140 ? 280.428 159.333 218.241 1.00 87.21  ? 143 ARG C CD    1 
ATOM   3950 N NE    . ARG B 2 140 ? 280.946 160.238 219.260 1.00 87.21  ? 143 ARG C NE    1 
ATOM   3951 C CZ    . ARG B 2 140 ? 280.951 161.562 219.152 1.00 87.21  ? 143 ARG C CZ    1 
ATOM   3952 N NH1   . ARG B 2 140 ? 280.460 162.144 218.068 1.00 87.21  ? 143 ARG C NH1   1 
ATOM   3953 N NH2   . ARG B 2 140 ? 281.443 162.306 220.131 1.00 87.21  ? 143 ARG C NH2   1 
ATOM   3954 N N     . GLY B 2 141 ? 282.489 162.579 215.542 1.00 86.98  ? 144 GLY C N     1 
ATOM   3955 C CA    . GLY B 2 141 ? 283.212 163.832 215.574 1.00 86.98  ? 144 GLY C CA    1 
ATOM   3956 C C     . GLY B 2 141 ? 283.397 164.447 214.206 1.00 86.98  ? 144 GLY C C     1 
ATOM   3957 O O     . GLY B 2 141 ? 283.625 165.654 214.087 1.00 86.98  ? 144 GLY C O     1 
ATOM   3958 N N     . LYS B 2 142 ? 283.305 163.624 213.165 1.00 87.78  ? 145 LYS C N     1 
ATOM   3959 C CA    . LYS B 2 142 ? 283.477 164.119 211.808 1.00 87.78  ? 145 LYS C CA    1 
ATOM   3960 C C     . LYS B 2 142 ? 282.328 165.049 211.445 1.00 87.78  ? 145 LYS C C     1 
ATOM   3961 O O     . LYS B 2 142 ? 281.162 164.644 211.447 1.00 87.78  ? 145 LYS C O     1 
ATOM   3962 C CB    . LYS B 2 142 ? 283.557 162.955 210.824 1.00 87.78  ? 145 LYS C CB    1 
ATOM   3963 C CG    . LYS B 2 142 ? 284.497 161.848 211.264 1.00 87.78  ? 145 LYS C CG    1 
ATOM   3964 C CD    . LYS B 2 142 ? 284.665 160.796 210.185 1.00 87.78  ? 145 LYS C CD    1 
ATOM   3965 C CE    . LYS B 2 142 ? 285.396 161.360 208.975 1.00 87.78  ? 145 LYS C CE    1 
ATOM   3966 N NZ    . LYS B 2 142 ? 285.472 160.382 207.852 1.00 87.78  ? 145 LYS C NZ    1 
ATOM   3967 N N     . LYS B 2 143 ? 282.662 166.297 211.132 1.00 86.15  ? 146 LYS C N     1 
ATOM   3968 C CA    . LYS B 2 143 ? 281.661 167.303 210.821 1.00 86.15  ? 146 LYS C CA    1 
ATOM   3969 C C     . LYS B 2 143 ? 280.926 166.942 209.532 1.00 86.15  ? 146 LYS C C     1 
ATOM   3970 O O     . LYS B 2 143 ? 281.247 165.969 208.846 1.00 86.15  ? 146 LYS C O     1 
ATOM   3971 C CB    . LYS B 2 143 ? 282.313 168.676 210.701 1.00 86.15  ? 146 LYS C CB    1 
ATOM   3972 C CG    . LYS B 2 143 ? 282.550 169.373 212.026 1.00 86.15  ? 146 LYS C CG    1 
ATOM   3973 C CD    . LYS B 2 143 ? 281.241 169.663 212.739 1.00 86.15  ? 146 LYS C CD    1 
ATOM   3974 C CE    . LYS B 2 143 ? 281.479 170.412 214.037 1.00 86.15  ? 146 LYS C CE    1 
ATOM   3975 N NZ    . LYS B 2 143 ? 280.207 170.658 214.765 1.00 86.15  ? 146 LYS C NZ    1 
ATOM   3976 N N     . ARG B 2 144 ? 279.916 167.748 209.203 1.00 81.43  ? 147 ARG C N     1 
ATOM   3977 C CA    . ARG B 2 144 ? 279.167 167.525 207.971 1.00 81.43  ? 147 ARG C CA    1 
ATOM   3978 C C     . ARG B 2 144 ? 280.033 167.786 206.747 1.00 81.43  ? 147 ARG C C     1 
ATOM   3979 O O     . ARG B 2 144 ? 279.829 167.176 205.692 1.00 81.43  ? 147 ARG C O     1 
ATOM   3980 C CB    . ARG B 2 144 ? 277.924 168.415 207.953 1.00 81.43  ? 147 ARG C CB    1 
ATOM   3981 C CG    . ARG B 2 144 ? 277.037 168.241 206.734 1.00 81.43  ? 147 ARG C CG    1 
ATOM   3982 C CD    . ARG B 2 144 ? 275.710 168.949 206.927 1.00 81.43  ? 147 ARG C CD    1 
ATOM   3983 N NE    . ARG B 2 144 ? 274.806 168.733 205.804 1.00 81.43  ? 147 ARG C NE    1 
ATOM   3984 C CZ    . ARG B 2 144 ? 274.598 169.617 204.835 1.00 81.43  ? 147 ARG C CZ    1 
ATOM   3985 N NH1   . ARG B 2 144 ? 275.230 170.781 204.851 1.00 81.43  ? 147 ARG C NH1   1 
ATOM   3986 N NH2   . ARG B 2 144 ? 273.757 169.337 203.851 1.00 81.43  ? 147 ARG C NH2   1 
ATOM   3987 N N     . SER B 2 145 ? 281.014 168.675 206.875 1.00 86.77  ? 148 SER C N     1 
ATOM   3988 C CA    . SER B 2 145 ? 281.849 169.082 205.755 1.00 86.77  ? 148 SER C CA    1 
ATOM   3989 C C     . SER B 2 145 ? 282.998 168.123 205.478 1.00 86.77  ? 148 SER C C     1 
ATOM   3990 O O     . SER B 2 145 ? 283.709 168.311 204.485 1.00 86.77  ? 148 SER C O     1 
ATOM   3991 C CB    . SER B 2 145 ? 282.408 170.483 206.012 1.00 86.77  ? 148 SER C CB    1 
ATOM   3992 O OG    . SER B 2 145 ? 281.365 171.434 206.125 1.00 86.77  ? 148 SER C OG    1 
ATOM   3993 N N     . GLU B 2 146 ? 283.203 167.111 206.313 1.00 89.23  ? 149 GLU C N     1 
ATOM   3994 C CA    . GLU B 2 146 ? 284.343 166.215 206.166 1.00 89.23  ? 149 GLU C CA    1 
ATOM   3995 C C     . GLU B 2 146 ? 283.952 164.788 205.832 1.00 89.23  ? 149 GLU C C     1 
ATOM   3996 O O     . GLU B 2 146 ? 284.441 164.235 204.846 1.00 89.23  ? 149 GLU C O     1 
ATOM   3997 C CB    . GLU B 2 146 ? 285.182 166.219 207.449 1.00 89.23  ? 149 GLU C CB    1 
ATOM   3998 C CG    . GLU B 2 146 ? 285.876 167.539 207.719 1.00 89.23  ? 149 GLU C CG    1 
ATOM   3999 C CD    . GLU B 2 146 ? 286.691 167.516 208.992 1.00 89.23  ? 149 GLU C CD    1 
ATOM   4000 O OE1   . GLU B 2 146 ? 286.602 166.518 209.736 1.00 89.23  ? 149 GLU C OE1   1 
ATOM   4001 O OE2   . GLU B 2 146 ? 287.426 168.491 209.247 1.00 89.23  ? 149 GLU C OE2   1 
ATOM   4002 N N     . ALA B 2 147 ? 283.082 164.179 206.623 1.00 88.15  ? 150 ALA C N     1 
ATOM   4003 C CA    . ALA B 2 147 ? 282.672 162.814 206.376 1.00 88.15  ? 150 ALA C CA    1 
ATOM   4004 C C     . ALA B 2 147 ? 281.761 162.745 205.152 1.00 88.15  ? 150 ALA C C     1 
ATOM   4005 O O     . ALA B 2 147 ? 281.250 163.767 204.689 1.00 88.15  ? 150 ALA C O     1 
ATOM   4006 C CB    . ALA B 2 147 ? 281.959 162.260 207.606 1.00 88.15  ? 150 ALA C CB    1 
ATOM   4007 N N     . PRO B 2 148 ? 281.550 161.553 204.603 1.00 86.36  ? 151 PRO C N     1 
ATOM   4008 C CA    . PRO B 2 148 ? 280.615 161.405 203.486 1.00 86.36  ? 151 PRO C CA    1 
ATOM   4009 C C     . PRO B 2 148 ? 279.197 161.745 203.914 1.00 86.36  ? 151 PRO C C     1 
ATOM   4010 O O     . PRO B 2 148 ? 278.925 161.929 205.109 1.00 86.36  ? 151 PRO C O     1 
ATOM   4011 C CB    . PRO B 2 148 ? 280.749 159.921 203.113 1.00 86.36  ? 151 PRO C CB    1 
ATOM   4012 C CG    . PRO B 2 148 ? 282.086 159.533 203.593 1.00 86.36  ? 151 PRO C CG    1 
ATOM   4013 C CD    . PRO B 2 148 ? 282.307 160.313 204.844 1.00 86.36  ? 151 PRO C CD    1 
ATOM   4014 N N     . PRO B 2 149 ? 278.263 161.837 202.968 1.00 80.21  ? 152 PRO C N     1 
ATOM   4015 C CA    . PRO B 2 149 ? 276.884 162.199 203.322 1.00 80.21  ? 152 PRO C CA    1 
ATOM   4016 C C     . PRO B 2 149 ? 276.067 161.043 203.874 1.00 80.21  ? 152 PRO C C     1 
ATOM   4017 O O     . PRO B 2 149 ? 275.421 160.331 203.109 1.00 80.21  ? 152 PRO C O     1 
ATOM   4018 C CB    . PRO B 2 149 ? 276.307 162.698 201.993 1.00 80.21  ? 152 PRO C CB    1 
ATOM   4019 C CG    . PRO B 2 149 ? 277.089 161.981 200.965 1.00 80.21  ? 152 PRO C CG    1 
ATOM   4020 C CD    . PRO B 2 149 ? 278.475 161.866 201.511 1.00 80.21  ? 152 PRO C CD    1 
ATOM   4021 N N     . HIS B 2 150 ? 276.119 160.816 205.181 1.00 79.18  ? 153 HIS C N     1 
ATOM   4022 C CA    . HIS B 2 150 ? 275.313 159.803 205.844 1.00 79.18  ? 153 HIS C CA    1 
ATOM   4023 C C     . HIS B 2 150 ? 274.287 160.464 206.755 1.00 79.18  ? 153 HIS C C     1 
ATOM   4024 O O     . HIS B 2 150 ? 274.427 161.626 207.141 1.00 79.18  ? 153 HIS C O     1 
ATOM   4025 C CB    . HIS B 2 150 ? 276.200 158.862 206.665 1.00 79.18  ? 153 HIS C CB    1 
ATOM   4026 C CG    . HIS B 2 150 ? 275.705 157.451 206.737 1.00 79.18  ? 153 HIS C CG    1 
ATOM   4027 N ND1   . HIS B 2 150 ? 274.444 157.124 207.181 1.00 79.18  ? 153 HIS C ND1   1 
ATOM   4028 C CD2   . HIS B 2 150 ? 276.320 156.279 206.458 1.00 79.18  ? 153 HIS C CD2   1 
ATOM   4029 C CE1   . HIS B 2 150 ? 274.295 155.813 207.153 1.00 79.18  ? 153 HIS C CE1   1 
ATOM   4030 N NE2   . HIS B 2 150 ? 275.420 155.276 206.720 1.00 79.18  ? 153 HIS C NE2   1 
ATOM   4031 N N     . ILE B 2 151 ? 273.243 159.707 207.102 1.00 78.99  ? 154 ILE C N     1 
ATOM   4032 C CA    . ILE B 2 151 ? 272.338 160.165 208.151 1.00 78.99  ? 154 ILE C CA    1 
ATOM   4033 C C     . ILE B 2 151 ? 273.061 160.183 209.486 1.00 78.99  ? 154 ILE C C     1 
ATOM   4034 O O     . ILE B 2 151 ? 272.683 160.930 210.400 1.00 78.99  ? 154 ILE C O     1 
ATOM   4035 C CB    . ILE B 2 151 ? 271.079 159.284 208.222 1.00 78.99  ? 154 ILE C CB    1 
ATOM   4036 C CG1   . ILE B 2 151 ? 271.452 157.834 208.513 1.00 78.99  ? 154 ILE C CG1   1 
ATOM   4037 C CG2   . ILE B 2 151 ? 270.309 159.353 206.929 1.00 78.99  ? 154 ILE C CG2   1 
ATOM   4038 C CD1   . ILE B 2 151 ? 270.275 156.986 208.906 1.00 78.99  ? 154 ILE C CD1   1 
ATOM   4039 N N     . PHE B 2 152 ? 274.094 159.348 209.630 1.00 78.26  ? 155 PHE C N     1 
ATOM   4040 C CA    . PHE B 2 152 ? 274.915 159.387 210.831 1.00 78.26  ? 155 PHE C CA    1 
ATOM   4041 C C     . PHE B 2 152 ? 275.546 160.753 211.014 1.00 78.26  ? 155 PHE C C     1 
ATOM   4042 O O     . PHE B 2 152 ? 275.765 161.182 212.147 1.00 78.26  ? 155 PHE C O     1 
ATOM   4043 C CB    . PHE B 2 152 ? 276.000 158.313 210.775 1.00 78.26  ? 155 PHE C CB    1 
ATOM   4044 C CG    . PHE B 2 152 ? 275.493 156.918 210.983 1.00 78.26  ? 155 PHE C CG    1 
ATOM   4045 C CD1   . PHE B 2 152 ? 274.165 156.677 211.273 1.00 78.26  ? 155 PHE C CD1   1 
ATOM   4046 C CD2   . PHE B 2 152 ? 276.359 155.847 210.910 1.00 78.26  ? 155 PHE C CD2   1 
ATOM   4047 C CE1   . PHE B 2 152 ? 273.714 155.394 211.467 1.00 78.26  ? 155 PHE C CE1   1 
ATOM   4048 C CE2   . PHE B 2 152 ? 275.911 154.567 211.106 1.00 78.26  ? 155 PHE C CE2   1 
ATOM   4049 C CZ    . PHE B 2 152 ? 274.591 154.341 211.388 1.00 78.26  ? 155 PHE C CZ    1 
ATOM   4050 N N     . SER B 2 153 ? 275.823 161.462 209.921 1.00 78.67  ? 156 SER C N     1 
ATOM   4051 C CA    . SER B 2 153 ? 276.336 162.819 210.051 1.00 78.67  ? 156 SER C CA    1 
ATOM   4052 C C     . SER B 2 153 ? 275.288 163.739 210.662 1.00 78.67  ? 156 SER C C     1 
ATOM   4053 O O     . SER B 2 153 ? 275.603 164.554 211.535 1.00 78.67  ? 156 SER C O     1 
ATOM   4054 C CB    . SER B 2 153 ? 276.791 163.342 208.692 1.00 78.67  ? 156 SER C CB    1 
ATOM   4055 O OG    . SER B 2 153 ? 277.645 164.460 208.839 1.00 78.67  ? 156 SER C OG    1 
ATOM   4056 N N     . ILE B 2 154 ? 274.030 163.596 210.241 1.00 78.39  ? 157 ILE C N     1 
ATOM   4057 C CA    . ILE B 2 154 ? 272.945 164.373 210.835 1.00 78.39  ? 157 ILE C CA    1 
ATOM   4058 C C     . ILE B 2 154 ? 272.823 164.063 212.321 1.00 78.39  ? 157 ILE C C     1 
ATOM   4059 O O     . ILE B 2 154 ? 272.754 164.968 213.160 1.00 78.39  ? 157 ILE C O     1 
ATOM   4060 C CB    . ILE B 2 154 ? 271.622 164.101 210.096 1.00 78.39  ? 157 ILE C CB    1 
ATOM   4061 C CG1   . ILE B 2 154 ? 271.592 164.832 208.754 1.00 78.39  ? 157 ILE C CG1   1 
ATOM   4062 C CG2   . ILE B 2 154 ? 270.438 164.511 210.950 1.00 78.39  ? 157 ILE C CG2   1 
ATOM   4063 C CD1   . ILE B 2 154 ? 271.728 166.327 208.876 1.00 78.39  ? 157 ILE C CD1   1 
ATOM   4064 N N     . SER B 2 155 ? 272.797 162.773 212.666 1.00 78.42  ? 158 SER C N     1 
ATOM   4065 C CA    . SER B 2 155 ? 272.627 162.379 214.062 1.00 78.42  ? 158 SER C CA    1 
ATOM   4066 C C     . SER B 2 155 ? 273.787 162.866 214.921 1.00 78.42  ? 158 SER C C     1 
ATOM   4067 O O     . SER B 2 155 ? 273.580 163.433 216.002 1.00 78.42  ? 158 SER C O     1 
ATOM   4068 C CB    . SER B 2 155 ? 272.496 160.861 214.161 1.00 78.42  ? 158 SER C CB    1 
ATOM   4069 O OG    . SER B 2 155 ? 271.355 160.402 213.464 1.00 78.42  ? 158 SER C OG    1 
ATOM   4070 N N     . ASP B 2 156 ? 275.016 162.663 214.451 1.00 81.23  ? 159 ASP C N     1 
ATOM   4071 C CA    . ASP B 2 156 ? 276.178 163.045 215.232 1.00 81.23  ? 159 ASP C CA    1 
ATOM   4072 C C     . ASP B 2 156 ? 276.311 164.554 215.337 1.00 81.23  ? 159 ASP C C     1 
ATOM   4073 O O     . ASP B 2 156 ? 276.786 165.055 216.358 1.00 81.23  ? 159 ASP C O     1 
ATOM   4074 C CB    . ASP B 2 156 ? 277.434 162.436 214.620 1.00 81.23  ? 159 ASP C CB    1 
ATOM   4075 C CG    . ASP B 2 156 ? 278.552 162.286 215.622 1.00 81.23  ? 159 ASP C CG    1 
ATOM   4076 O OD1   . ASP B 2 156 ? 279.063 163.316 216.106 1.00 81.23  ? 159 ASP C OD1   1 
ATOM   4077 O OD2   . ASP B 2 156 ? 278.920 161.135 215.930 1.00 81.23  ? 159 ASP C OD2   1 
ATOM   4078 N N     . ASN B 2 157 ? 275.878 165.303 214.321 1.00 80.00  ? 160 ASN C N     1 
ATOM   4079 C CA    . ASN B 2 157 ? 275.915 166.754 214.443 1.00 80.00  ? 160 ASN C CA    1 
ATOM   4080 C C     . ASN B 2 157 ? 274.825 167.263 215.372 1.00 80.00  ? 160 ASN C C     1 
ATOM   4081 O O     . ASN B 2 157 ? 275.039 168.243 216.088 1.00 80.00  ? 160 ASN C O     1 
ATOM   4082 C CB    . ASN B 2 157 ? 275.803 167.396 213.066 1.00 80.00  ? 160 ASN C CB    1 
ATOM   4083 C CG    . ASN B 2 157 ? 277.059 167.216 212.250 1.00 80.00  ? 160 ASN C CG    1 
ATOM   4084 O OD1   . ASN B 2 157 ? 278.166 167.367 212.761 1.00 80.00  ? 160 ASN C OD1   1 
ATOM   4085 N ND2   . ASN B 2 157 ? 276.898 166.875 210.981 1.00 80.00  ? 160 ASN C ND2   1 
ATOM   4086 N N     . ALA B 2 158 ? 273.666 166.602 215.401 1.00 78.49  ? 161 ALA C N     1 
ATOM   4087 C CA    . ALA B 2 158 ? 272.667 166.932 216.410 1.00 78.49  ? 161 ALA C CA    1 
ATOM   4088 C C     . ALA B 2 158 ? 273.213 166.691 217.810 1.00 78.49  ? 161 ALA C C     1 
ATOM   4089 O O     . ALA B 2 158 ? 273.022 167.513 218.712 1.00 78.49  ? 161 ALA C O     1 
ATOM   4090 C CB    . ALA B 2 158 ? 271.397 166.115 216.180 1.00 78.49  ? 161 ALA C CB    1 
ATOM   4091 N N     . TYR B 2 159 ? 273.915 165.575 217.999 1.00 79.89  ? 162 TYR C N     1 
ATOM   4092 C CA    . TYR B 2 159 ? 274.522 165.276 219.293 1.00 79.89  ? 162 TYR C CA    1 
ATOM   4093 C C     . TYR B 2 159 ? 275.574 166.319 219.668 1.00 79.89  ? 162 TYR C C     1 
ATOM   4094 O O     . TYR B 2 159 ? 275.593 166.828 220.798 1.00 79.89  ? 162 TYR C O     1 
ATOM   4095 C CB    . TYR B 2 159 ? 275.123 163.872 219.242 1.00 79.89  ? 162 TYR C CB    1 
ATOM   4096 C CG    . TYR B 2 159 ? 275.609 163.324 220.558 1.00 79.89  ? 162 TYR C CG    1 
ATOM   4097 C CD1   . TYR B 2 159 ? 274.798 162.511 221.333 1.00 79.89  ? 162 TYR C CD1   1 
ATOM   4098 C CD2   . TYR B 2 159 ? 276.895 163.583 221.006 1.00 79.89  ? 162 TYR C CD2   1 
ATOM   4099 C CE1   . TYR B 2 159 ? 275.243 161.996 222.531 1.00 79.89  ? 162 TYR C CE1   1 
ATOM   4100 C CE2   . TYR B 2 159 ? 277.349 163.069 222.199 1.00 79.89  ? 162 TYR C CE2   1 
ATOM   4101 C CZ    . TYR B 2 159 ? 276.520 162.279 222.959 1.00 79.89  ? 162 TYR C CZ    1 
ATOM   4102 O OH    . TYR B 2 159 ? 276.975 161.768 224.151 1.00 79.89  ? 162 TYR C OH    1 
ATOM   4103 N N     . GLN B 2 160 ? 276.464 166.643 218.728 1.00 80.84  ? 163 GLN C N     1 
ATOM   4104 C CA    . GLN B 2 160 ? 277.508 167.628 218.992 1.00 80.84  ? 163 GLN C CA    1 
ATOM   4105 C C     . GLN B 2 160 ? 276.917 168.993 219.307 1.00 80.84  ? 163 GLN C C     1 
ATOM   4106 O O     . GLN B 2 160 ? 277.411 169.696 220.193 1.00 80.84  ? 163 GLN C O     1 
ATOM   4107 C CB    . GLN B 2 160 ? 278.456 167.724 217.799 1.00 80.84  ? 163 GLN C CB    1 
ATOM   4108 C CG    . GLN B 2 160 ? 279.299 166.484 217.568 1.00 80.84  ? 163 GLN C CG    1 
ATOM   4109 C CD    . GLN B 2 160 ? 279.969 166.480 216.207 1.00 80.84  ? 163 GLN C CD    1 
ATOM   4110 O OE1   . GLN B 2 160 ? 280.753 167.371 215.887 1.00 80.84  ? 163 GLN C OE1   1 
ATOM   4111 N NE2   . GLN B 2 160 ? 279.661 165.474 215.399 1.00 80.84  ? 163 GLN C NE2   1 
ATOM   4112 N N     . TYR B 2 161 ? 275.865 169.392 218.590 1.00 79.95  ? 164 TYR C N     1 
ATOM   4113 C CA    . TYR B 2 161 ? 275.217 170.662 218.890 1.00 79.95  ? 164 TYR C CA    1 
ATOM   4114 C C     . TYR B 2 161 ? 274.570 170.633 220.266 1.00 79.95  ? 164 TYR C C     1 
ATOM   4115 O O     . TYR B 2 161 ? 274.647 171.614 221.013 1.00 79.95  ? 164 TYR C O     1 
ATOM   4116 C CB    . TYR B 2 161 ? 274.179 170.993 217.821 1.00 79.95  ? 164 TYR C CB    1 
ATOM   4117 C CG    . TYR B 2 161 ? 274.749 171.547 216.536 1.00 79.95  ? 164 TYR C CG    1 
ATOM   4118 C CD1   . TYR B 2 161 ? 275.711 172.544 216.553 1.00 79.95  ? 164 TYR C CD1   1 
ATOM   4119 C CD2   . TYR B 2 161 ? 274.309 171.085 215.304 1.00 79.95  ? 164 TYR C CD2   1 
ATOM   4120 C CE1   . TYR B 2 161 ? 276.227 173.054 215.384 1.00 79.95  ? 164 TYR C CE1   1 
ATOM   4121 C CE2   . TYR B 2 161 ? 274.819 171.589 214.131 1.00 79.95  ? 164 TYR C CE2   1 
ATOM   4122 C CZ    . TYR B 2 161 ? 275.777 172.573 214.176 1.00 79.95  ? 164 TYR C CZ    1 
ATOM   4123 O OH    . TYR B 2 161 ? 276.289 173.081 213.005 1.00 79.95  ? 164 TYR C OH    1 
ATOM   4124 N N     . MET B 2 162 ? 273.924 169.520 220.617 1.00 78.65  ? 165 MET C N     1 
ATOM   4125 C CA    . MET B 2 162 ? 273.310 169.405 221.934 1.00 78.65  ? 165 MET C CA    1 
ATOM   4126 C C     . MET B 2 162 ? 274.343 169.561 223.037 1.00 78.65  ? 165 MET C C     1 
ATOM   4127 O O     . MET B 2 162 ? 274.068 170.175 224.074 1.00 78.65  ? 165 MET C O     1 
ATOM   4128 C CB    . MET B 2 162 ? 272.597 168.062 222.064 1.00 78.65  ? 165 MET C CB    1 
ATOM   4129 C CG    . MET B 2 162 ? 271.716 167.945 223.286 1.00 78.65  ? 165 MET C CG    1 
ATOM   4130 S SD    . MET B 2 162 ? 271.203 166.246 223.573 1.00 78.65  ? 165 MET C SD    1 
ATOM   4131 C CE    . MET B 2 162 ? 272.795 165.449 223.740 1.00 78.65  ? 165 MET C CE    1 
ATOM   4132 N N     . LEU B 2 163 ? 275.540 169.014 222.835 1.00 78.60  ? 166 LEU C N     1 
ATOM   4133 C CA    . LEU B 2 163 ? 276.558 169.103 223.876 1.00 78.60  ? 166 LEU C CA    1 
ATOM   4134 C C     . LEU B 2 163 ? 277.401 170.370 223.795 1.00 78.60  ? 166 LEU C C     1 
ATOM   4135 O O     . LEU B 2 163 ? 278.125 170.671 224.748 1.00 78.60  ? 166 LEU C O     1 
ATOM   4136 C CB    . LEU B 2 163 ? 277.473 167.881 223.836 1.00 78.60  ? 166 LEU C CB    1 
ATOM   4137 C CG    . LEU B 2 163 ? 276.823 166.580 224.293 1.00 78.60  ? 166 LEU C CG    1 
ATOM   4138 C CD1   . LEU B 2 163 ? 277.878 165.516 224.496 1.00 78.60  ? 166 LEU C CD1   1 
ATOM   4139 C CD2   . LEU B 2 163 ? 276.039 166.806 225.566 1.00 78.60  ? 166 LEU C CD2   1 
ATOM   4140 N N     . THR B 2 164 ? 277.336 171.116 222.694 1.00 82.74  ? 167 THR C N     1 
ATOM   4141 C CA    . THR B 2 164 ? 278.124 172.335 222.565 1.00 82.74  ? 167 THR C CA    1 
ATOM   4142 C C     . THR B 2 164 ? 277.337 173.600 222.867 1.00 82.74  ? 167 THR C C     1 
ATOM   4143 O O     . THR B 2 164 ? 277.866 174.503 223.522 1.00 82.74  ? 167 THR C O     1 
ATOM   4144 C CB    . THR B 2 164 ? 278.709 172.438 221.153 1.00 82.74  ? 167 THR C CB    1 
ATOM   4145 O OG1   . THR B 2 164 ? 279.497 171.275 220.878 1.00 82.74  ? 167 THR C OG1   1 
ATOM   4146 C CG2   . THR B 2 164 ? 279.584 173.670 221.023 1.00 82.74  ? 167 THR C CG2   1 
ATOM   4147 N N     . ASP B 2 165 ? 276.084 173.684 222.425 1.00 85.80  ? 168 ASP C N     1 
ATOM   4148 C CA    . ASP B 2 165 ? 275.249 174.844 222.683 1.00 85.80  ? 168 ASP C CA    1 
ATOM   4149 C C     . ASP B 2 165 ? 274.225 174.618 223.782 1.00 85.80  ? 168 ASP C C     1 
ATOM   4150 O O     . ASP B 2 165 ? 273.560 175.579 224.185 1.00 85.80  ? 168 ASP C O     1 
ATOM   4151 C CB    . ASP B 2 165 ? 274.512 175.271 221.404 1.00 85.80  ? 168 ASP C CB    1 
ATOM   4152 C CG    . ASP B 2 165 ? 275.446 175.822 220.350 1.00 85.80  ? 168 ASP C CG    1 
ATOM   4153 O OD1   . ASP B 2 165 ? 276.495 176.385 220.721 1.00 85.80  ? 168 ASP C OD1   1 
ATOM   4154 O OD2   . ASP B 2 165 ? 275.131 175.694 219.149 1.00 85.80  ? 168 ASP C OD2   1 
ATOM   4155 N N     . ARG B 2 166 ? 274.084 173.388 224.277 1.00 87.06  ? 169 ARG C N     1 
ATOM   4156 C CA    . ARG B 2 166 ? 273.089 173.048 225.293 1.00 87.06  ? 169 ARG C CA    1 
ATOM   4157 C C     . ARG B 2 166 ? 271.687 173.455 224.853 1.00 87.06  ? 169 ARG C C     1 
ATOM   4158 O O     . ARG B 2 166 ? 270.962 174.139 225.577 1.00 87.06  ? 169 ARG C O     1 
ATOM   4159 C CB    . ARG B 2 166 ? 273.438 173.663 226.647 1.00 87.06  ? 169 ARG C CB    1 
ATOM   4160 C CG    . ARG B 2 166 ? 274.468 172.874 227.433 1.00 87.06  ? 169 ARG C CG    1 
ATOM   4161 C CD    . ARG B 2 166 ? 275.872 173.209 226.989 1.00 87.06  ? 169 ARG C CD    1 
ATOM   4162 N NE    . ARG B 2 166 ? 276.133 174.639 227.097 1.00 87.06  ? 169 ARG C NE    1 
ATOM   4163 C CZ    . ARG B 2 166 ? 276.491 175.246 228.221 1.00 87.06  ? 169 ARG C CZ    1 
ATOM   4164 N NH1   . ARG B 2 166 ? 276.626 174.547 229.340 1.00 87.06  ? 169 ARG C NH1   1 
ATOM   4165 N NH2   . ARG B 2 166 ? 276.710 176.553 228.229 1.00 87.06  ? 169 ARG C NH2   1 
ATOM   4166 N N     . GLU B 2 167 ? 271.312 173.043 223.648 1.00 82.59  ? 170 GLU C N     1 
ATOM   4167 C CA    . GLU B 2 167 ? 269.972 173.239 223.121 1.00 82.59  ? 170 GLU C CA    1 
ATOM   4168 C C     . GLU B 2 167 ? 269.323 171.890 222.852 1.00 82.59  ? 170 GLU C C     1 
ATOM   4169 O O     . GLU B 2 167 ? 270.010 170.909 222.556 1.00 82.59  ? 170 GLU C O     1 
ATOM   4170 C CB    . GLU B 2 167 ? 270.001 174.053 221.829 1.00 82.59  ? 170 GLU C CB    1 
ATOM   4171 C CG    . GLU B 2 167 ? 270.643 175.412 221.959 1.00 82.59  ? 170 GLU C CG    1 
ATOM   4172 C CD    . GLU B 2 167 ? 270.585 176.197 220.667 1.00 82.59  ? 170 GLU C CD    1 
ATOM   4173 O OE1   . GLU B 2 167 ? 270.579 175.567 219.590 1.00 82.59  ? 170 GLU C OE1   1 
ATOM   4174 O OE2   . GLU B 2 167 ? 270.543 177.443 220.726 1.00 82.59  ? 170 GLU C OE2   1 
ATOM   4175 N N     . ASN B 2 168 ? 268.002 171.843 222.965 1.00 76.01  ? 171 ASN C N     1 
ATOM   4176 C CA    . ASN B 2 168 ? 267.265 170.692 222.474 1.00 76.01  ? 171 ASN C CA    1 
ATOM   4177 C C     . ASN B 2 168 ? 267.314 170.663 220.951 1.00 76.01  ? 171 ASN C C     1 
ATOM   4178 O O     . ASN B 2 168 ? 267.376 171.702 220.291 1.00 76.01  ? 171 ASN C O     1 
ATOM   4179 C CB    . ASN B 2 168 ? 265.818 170.741 222.954 1.00 76.01  ? 171 ASN C CB    1 
ATOM   4180 C CG    . ASN B 2 168 ? 265.706 170.885 224.453 1.00 76.01  ? 171 ASN C CG    1 
ATOM   4181 O OD1   . ASN B 2 168 ? 266.610 170.508 225.193 1.00 76.01  ? 171 ASN C OD1   1 
ATOM   4182 N ND2   . ASN B 2 168 ? 264.588 171.430 224.912 1.00 76.01  ? 171 ASN C ND2   1 
ATOM   4183 N N     . GLN B 2 169 ? 267.289 169.459 220.389 1.00 71.74  ? 172 GLN C N     1 
ATOM   4184 C CA    . GLN B 2 169 ? 267.394 169.277 218.951 1.00 71.74  ? 172 GLN C CA    1 
ATOM   4185 C C     . GLN B 2 169 ? 266.238 168.419 218.462 1.00 71.74  ? 172 GLN C C     1 
ATOM   4186 O O     . GLN B 2 169 ? 265.620 167.682 219.232 1.00 71.74  ? 172 GLN C O     1 
ATOM   4187 C CB    . GLN B 2 169 ? 268.729 168.630 218.570 1.00 71.74  ? 172 GLN C CB    1 
ATOM   4188 C CG    . GLN B 2 169 ? 269.934 169.257 219.243 1.00 71.74  ? 172 GLN C CG    1 
ATOM   4189 C CD    . GLN B 2 169 ? 270.524 170.387 218.441 1.00 71.74  ? 172 GLN C CD    1 
ATOM   4190 O OE1   . GLN B 2 169 ? 270.365 170.445 217.225 1.00 71.74  ? 172 GLN C OE1   1 
ATOM   4191 N NE2   . GLN B 2 169 ? 271.206 171.300 219.117 1.00 71.74  ? 172 GLN C NE2   1 
ATOM   4192 N N     . SER B 2 170 ? 265.953 168.511 217.165 1.00 66.63  ? 173 SER C N     1 
ATOM   4193 C CA    . SER B 2 170 ? 264.859 167.762 216.565 1.00 66.63  ? 173 SER C CA    1 
ATOM   4194 C C     . SER B 2 170 ? 265.287 167.211 215.215 1.00 66.63  ? 173 SER C C     1 
ATOM   4195 O O     . SER B 2 170 ? 266.069 167.832 214.493 1.00 66.63  ? 173 SER C O     1 
ATOM   4196 C CB    . SER B 2 170 ? 263.607 168.624 216.390 1.00 66.63  ? 173 SER C CB    1 
ATOM   4197 O OG    . SER B 2 170 ? 263.336 169.361 217.564 1.00 66.63  ? 173 SER C OG    1 
ATOM   4198 N N     . ILE B 2 171 ? 264.757 166.039 214.881 1.00 64.33  ? 174 ILE C N     1 
ATOM   4199 C CA    . ILE B 2 171 ? 265.036 165.369 213.617 1.00 64.33  ? 174 ILE C CA    1 
ATOM   4200 C C     . ILE B 2 171 ? 263.700 165.206 212.905 1.00 64.33  ? 174 ILE C C     1 
ATOM   4201 O O     . ILE B 2 171 ? 262.996 164.213 213.112 1.00 64.33  ? 174 ILE C O     1 
ATOM   4202 C CB    . ILE B 2 171 ? 265.722 164.014 213.817 1.00 64.33  ? 174 ILE C CB    1 
ATOM   4203 C CG1   . ILE B 2 171 ? 266.988 164.162 214.660 1.00 64.33  ? 174 ILE C CG1   1 
ATOM   4204 C CG2   . ILE B 2 171 ? 266.066 163.392 212.477 1.00 64.33  ? 174 ILE C CG2   1 
ATOM   4205 C CD1   . ILE B 2 171 ? 268.046 165.018 214.030 1.00 64.33  ? 174 ILE C CD1   1 
ATOM   4206 N N     . LEU B 2 172 ? 263.345 166.169 212.060 1.00 62.42  ? 175 LEU C N     1 
ATOM   4207 C CA    . LEU B 2 172 ? 262.093 166.123 211.312 1.00 62.42  ? 175 LEU C CA    1 
ATOM   4208 C C     . LEU B 2 172 ? 262.278 165.205 210.109 1.00 62.42  ? 175 LEU C C     1 
ATOM   4209 O O     . LEU B 2 172 ? 262.981 165.553 209.156 1.00 62.42  ? 175 LEU C O     1 
ATOM   4210 C CB    . LEU B 2 172 ? 261.668 167.521 210.873 1.00 62.42  ? 175 LEU C CB    1 
ATOM   4211 C CG    . LEU B 2 172 ? 261.112 168.475 211.931 1.00 62.42  ? 175 LEU C CG    1 
ATOM   4212 C CD1   . LEU B 2 172 ? 262.218 169.092 212.756 1.00 62.42  ? 175 LEU C CD1   1 
ATOM   4213 C CD2   . LEU B 2 172 ? 260.280 169.557 211.275 1.00 62.42  ? 175 LEU C CD2   1 
ATOM   4214 N N     . ILE B 2 173 ? 261.644 164.040 210.150 1.00 66.86  ? 176 ILE C N     1 
ATOM   4215 C CA    . ILE B 2 173 ? 261.807 163.017 209.127 1.00 66.86  ? 176 ILE C CA    1 
ATOM   4216 C C     . ILE B 2 173 ? 260.517 162.902 208.323 1.00 66.86  ? 176 ILE C C     1 
ATOM   4217 O O     . ILE B 2 173 ? 259.431 163.249 208.798 1.00 66.86  ? 176 ILE C O     1 
ATOM   4218 C CB    . ILE B 2 173 ? 262.198 161.672 209.775 1.00 66.86  ? 176 ILE C CB    1 
ATOM   4219 C CG1   . ILE B 2 173 ? 262.587 160.639 208.723 1.00 66.86  ? 176 ILE C CG1   1 
ATOM   4220 C CG2   . ILE B 2 173 ? 261.068 161.143 210.623 1.00 66.86  ? 176 ILE C CG2   1 
ATOM   4221 C CD1   . ILE B 2 173 ? 263.130 159.369 209.314 1.00 66.86  ? 176 ILE C CD1   1 
ATOM   4222 N N     . THR B 2 174 ? 260.649 162.433 207.083 1.00 74.16  ? 177 THR C N     1 
ATOM   4223 C CA    . THR B 2 174 ? 259.490 162.200 206.230 1.00 74.16  ? 177 THR C CA    1 
ATOM   4224 C C     . THR B 2 174 ? 258.568 161.151 206.839 1.00 74.16  ? 177 THR C C     1 
ATOM   4225 O O     . THR B 2 174 ? 259.022 160.136 207.372 1.00 74.16  ? 177 THR C O     1 
ATOM   4226 C CB    . THR B 2 174 ? 259.944 161.749 204.845 1.00 74.16  ? 177 THR C CB    1 
ATOM   4227 O OG1   . THR B 2 174 ? 260.676 162.805 204.218 1.00 74.16  ? 177 THR C OG1   1 
ATOM   4228 C CG2   . THR B 2 174 ? 258.759 161.369 203.979 1.00 74.16  ? 177 THR C CG2   1 
ATOM   4229 N N     . GLY B 2 175 ? 257.261 161.399 206.754 1.00 81.85  ? 178 GLY C N     1 
ATOM   4230 C CA    . GLY B 2 175 ? 256.286 160.477 207.299 1.00 81.85  ? 178 GLY C CA    1 
ATOM   4231 C C     . GLY B 2 175 ? 255.278 159.946 206.300 1.00 81.85  ? 178 GLY C C     1 
ATOM   4232 O O     . GLY B 2 175 ? 254.582 158.965 206.580 1.00 81.85  ? 178 GLY C O     1 
ATOM   4233 N N     . GLU B 2 176 ? 255.186 160.584 205.131 1.00 85.67  ? 179 GLU C N     1 
ATOM   4234 C CA    . GLU B 2 176 ? 254.200 160.193 204.130 1.00 85.67  ? 179 GLU C CA    1 
ATOM   4235 C C     . GLU B 2 176 ? 254.600 158.930 203.375 1.00 85.67  ? 179 GLU C C     1 
ATOM   4236 O O     . GLU B 2 176 ? 253.728 158.249 202.825 1.00 85.67  ? 179 GLU C O     1 
ATOM   4237 C CB    . GLU B 2 176 ? 253.983 161.347 203.144 1.00 85.67  ? 179 GLU C CB    1 
ATOM   4238 C CG    . GLU B 2 176 ? 252.891 161.126 202.105 1.00 85.67  ? 179 GLU C CG    1 
ATOM   4239 C CD    . GLU B 2 176 ? 251.501 161.086 202.708 1.00 85.67  ? 179 GLU C CD    1 
ATOM   4240 O OE1   . GLU B 2 176 ? 251.296 161.692 203.781 1.00 85.67  ? 179 GLU C OE1   1 
ATOM   4241 O OE2   . GLU B 2 176 ? 250.609 160.452 202.107 1.00 85.67  ? 179 GLU C OE2   1 
ATOM   4242 N N     . SER B 2 177 ? 255.889 158.596 203.353 1.00 88.46  ? 180 SER C N     1 
ATOM   4243 C CA    . SER B 2 177 ? 256.350 157.427 202.620 1.00 88.46  ? 180 SER C CA    1 
ATOM   4244 C C     . SER B 2 177 ? 255.863 156.143 203.282 1.00 88.46  ? 180 SER C C     1 
ATOM   4245 O O     . SER B 2 177 ? 255.660 156.080 204.498 1.00 88.46  ? 180 SER C O     1 
ATOM   4246 C CB    . SER B 2 177 ? 257.874 157.430 202.538 1.00 88.46  ? 180 SER C CB    1 
ATOM   4247 O OG    . SER B 2 177 ? 258.337 158.566 201.831 1.00 88.46  ? 180 SER C OG    1 
ATOM   4248 N N     . GLY B 2 178 ? 255.673 155.109 202.464 1.00 92.45  ? 181 GLY C N     1 
ATOM   4249 C CA    . GLY B 2 178 ? 255.224 153.820 202.957 1.00 92.45  ? 181 GLY C CA    1 
ATOM   4250 C C     . GLY B 2 178 ? 256.216 153.141 203.879 1.00 92.45  ? 181 GLY C C     1 
ATOM   4251 O O     . GLY B 2 178 ? 255.951 152.973 205.073 1.00 92.45  ? 181 GLY C O     1 
ATOM   4252 N N     . ALA B 2 179 ? 257.365 152.749 203.336 1.00 93.33  ? 182 ALA C N     1 
ATOM   4253 C CA    . ALA B 2 179 ? 258.417 152.095 204.099 1.00 93.33  ? 182 ALA C CA    1 
ATOM   4254 C C     . ALA B 2 179 ? 259.720 152.864 203.920 1.00 93.33  ? 182 ALA C C     1 
ATOM   4255 O O     . ALA B 2 179 ? 259.817 153.793 203.113 1.00 93.33  ? 182 ALA C O     1 
ATOM   4256 C CB    . ALA B 2 179 ? 258.594 150.630 203.676 1.00 93.33  ? 182 ALA C CB    1 
ATOM   4257 N N     . GLY B 2 180 ? 260.732 152.464 204.688 1.00 87.18  ? 183 GLY C N     1 
ATOM   4258 C CA    . GLY B 2 180 ? 261.997 153.157 204.715 1.00 87.18  ? 183 GLY C CA    1 
ATOM   4259 C C     . GLY B 2 180 ? 262.094 154.237 205.769 1.00 87.18  ? 183 GLY C C     1 
ATOM   4260 O O     . GLY B 2 180 ? 263.205 154.666 206.098 1.00 87.18  ? 183 GLY C O     1 
ATOM   4261 N N     . LYS B 2 181 ? 260.960 154.691 206.299 1.00 81.70  ? 184 LYS C N     1 
ATOM   4262 C CA    . LYS B 2 181 ? 260.955 155.695 207.355 1.00 81.70  ? 184 LYS C CA    1 
ATOM   4263 C C     . LYS B 2 181 ? 261.099 155.055 208.730 1.00 81.70  ? 184 LYS C C     1 
ATOM   4264 O O     . LYS B 2 181 ? 261.833 155.562 209.589 1.00 81.70  ? 184 LYS C O     1 
ATOM   4265 C CB    . LYS B 2 181 ? 259.668 156.511 207.271 1.00 81.70  ? 184 LYS C CB    1 
ATOM   4266 C CG    . LYS B 2 181 ? 259.219 157.103 208.583 1.00 81.70  ? 184 LYS C CG    1 
ATOM   4267 C CD    . LYS B 2 181 ? 257.767 157.530 208.503 1.00 81.70  ? 184 LYS C CD    1 
ATOM   4268 C CE    . LYS B 2 181 ? 256.919 156.510 207.762 1.00 81.70  ? 184 LYS C CE    1 
ATOM   4269 N NZ    . LYS B 2 181 ? 255.500 156.947 207.646 1.00 81.70  ? 184 LYS C NZ    1 
ATOM   4270 N N     . THR B 2 182 ? 260.407 153.937 208.953 1.00 81.82  ? 185 THR C N     1 
ATOM   4271 C CA    . THR B 2 182 ? 260.494 153.258 210.241 1.00 81.82  ? 185 THR C CA    1 
ATOM   4272 C C     . THR B 2 182 ? 261.897 152.717 210.489 1.00 81.82  ? 185 THR C C     1 
ATOM   4273 O O     . THR B 2 182 ? 262.409 152.803 211.611 1.00 81.82  ? 185 THR C O     1 
ATOM   4274 C CB    . THR B 2 182 ? 259.445 152.145 210.321 1.00 81.82  ? 185 THR C CB    1 
ATOM   4275 O OG1   . THR B 2 182 ? 259.496 151.524 211.611 1.00 81.82  ? 185 THR C OG1   1 
ATOM   4276 C CG2   . THR B 2 182 ? 259.651 151.100 209.233 1.00 81.82  ? 185 THR C CG2   1 
ATOM   4277 N N     . VAL B 2 183 ? 262.546 152.181 209.453 1.00 81.06  ? 186 VAL C N     1 
ATOM   4278 C CA    . VAL B 2 183 ? 263.914 151.710 209.623 1.00 81.06  ? 186 VAL C CA    1 
ATOM   4279 C C     . VAL B 2 183 ? 264.855 152.882 209.854 1.00 81.06  ? 186 VAL C C     1 
ATOM   4280 O O     . VAL B 2 183 ? 265.822 152.765 210.611 1.00 81.06  ? 186 VAL C O     1 
ATOM   4281 C CB    . VAL B 2 183 ? 264.347 150.851 208.421 1.00 81.06  ? 186 VAL C CB    1 
ATOM   4282 C CG1   . VAL B 2 183 ? 263.356 149.727 208.201 1.00 81.06  ? 186 VAL C CG1   1 
ATOM   4283 C CG2   . VAL B 2 183 ? 264.470 151.692 207.166 1.00 81.06  ? 186 VAL C CG2   1 
ATOM   4284 N N     . ASN B 2 184 ? 264.575 154.038 209.250 1.00 79.75  ? 187 ASN C N     1 
ATOM   4285 C CA    . ASN B 2 184 ? 265.413 155.207 209.489 1.00 79.75  ? 187 ASN C CA    1 
ATOM   4286 C C     . ASN B 2 184 ? 265.298 155.679 210.930 1.00 79.75  ? 187 ASN C C     1 
ATOM   4287 O O     . ASN B 2 184 ? 266.309 156.007 211.562 1.00 79.75  ? 187 ASN C O     1 
ATOM   4288 C CB    . ASN B 2 184 ? 265.037 156.332 208.529 1.00 79.75  ? 187 ASN C CB    1 
ATOM   4289 C CG    . ASN B 2 184 ? 265.749 156.223 207.206 1.00 79.75  ? 187 ASN C CG    1 
ATOM   4290 O OD1   . ASN B 2 184 ? 266.966 156.057 207.158 1.00 79.75  ? 187 ASN C OD1   1 
ATOM   4291 N ND2   . ASN B 2 184 ? 264.996 156.317 206.120 1.00 79.75  ? 187 ASN C ND2   1 
ATOM   4292 N N     . THR B 2 185 ? 264.078 155.722 211.468 1.00 79.77  ? 188 THR C N     1 
ATOM   4293 C CA    . THR B 2 185 ? 263.915 156.086 212.872 1.00 79.77  ? 188 THR C CA    1 
ATOM   4294 C C     . THR B 2 185 ? 264.594 155.072 213.784 1.00 79.77  ? 188 THR C C     1 
ATOM   4295 O O     . THR B 2 185 ? 265.291 155.449 214.738 1.00 79.77  ? 188 THR C O     1 
ATOM   4296 C CB    . THR B 2 185 ? 262.434 156.206 213.218 1.00 79.77  ? 188 THR C CB    1 
ATOM   4297 O OG1   . THR B 2 185 ? 261.775 156.988 212.217 1.00 79.77  ? 188 THR C OG1   1 
ATOM   4298 C CG2   . THR B 2 185 ? 262.260 156.874 214.565 1.00 79.77  ? 188 THR C CG2   1 
ATOM   4299 N N     . LYS B 2 186 ? 264.405 153.779 213.504 1.00 80.91  ? 189 LYS C N     1 
ATOM   4300 C CA    . LYS B 2 186 ? 265.062 152.749 214.297 1.00 80.91  ? 189 LYS C CA    1 
ATOM   4301 C C     . LYS B 2 186 ? 266.573 152.929 214.292 1.00 80.91  ? 189 LYS C C     1 
ATOM   4302 O O     . LYS B 2 186 ? 267.223 152.806 215.333 1.00 80.91  ? 189 LYS C O     1 
ATOM   4303 C CB    . LYS B 2 186 ? 264.693 151.362 213.774 1.00 80.91  ? 189 LYS C CB    1 
ATOM   4304 C CG    . LYS B 2 186 ? 265.512 150.247 214.400 1.00 80.91  ? 189 LYS C CG    1 
ATOM   4305 C CD    . LYS B 2 186 ? 265.263 148.912 213.724 1.00 80.91  ? 189 LYS C CD    1 
ATOM   4306 C CE    . LYS B 2 186 ? 263.945 148.302 214.162 1.00 80.91  ? 189 LYS C CE    1 
ATOM   4307 N NZ    . LYS B 2 186 ? 263.789 146.911 213.655 1.00 80.91  ? 189 LYS C NZ    1 
ATOM   4308 N N     . ARG B 2 187 ? 267.148 153.254 213.137 1.00 80.47  ? 190 ARG C N     1 
ATOM   4309 C CA    . ARG B 2 187 ? 268.599 153.337 213.052 1.00 80.47  ? 190 ARG C CA    1 
ATOM   4310 C C     . ARG B 2 187 ? 269.142 154.631 213.640 1.00 80.47  ? 190 ARG C C     1 
ATOM   4311 O O     . ARG B 2 187 ? 270.248 154.631 214.184 1.00 80.47  ? 190 ARG C O     1 
ATOM   4312 C CB    . ARG B 2 187 ? 269.040 153.164 211.602 1.00 80.47  ? 190 ARG C CB    1 
ATOM   4313 C CG    . ARG B 2 187 ? 268.707 151.784 211.067 1.00 80.47  ? 190 ARG C CG    1 
ATOM   4314 C CD    . ARG B 2 187 ? 269.409 151.505 209.768 1.00 80.47  ? 190 ARG C CD    1 
ATOM   4315 N NE    . ARG B 2 187 ? 268.679 150.558 208.930 1.00 80.47  ? 190 ARG C NE    1 
ATOM   4316 C CZ    . ARG B 2 187 ? 268.659 149.245 209.125 1.00 80.47  ? 190 ARG C CZ    1 
ATOM   4317 N NH1   . ARG B 2 187 ? 269.335 148.710 210.133 1.00 80.47  ? 190 ARG C NH1   1 
ATOM   4318 N NH2   . ARG B 2 187 ? 267.964 148.466 208.309 1.00 80.47  ? 190 ARG C NH2   1 
ATOM   4319 N N     . VAL B 2 188 ? 268.389 155.728 213.574 1.00 76.76  ? 191 VAL C N     1 
ATOM   4320 C CA    . VAL B 2 188 ? 268.800 156.929 214.296 1.00 76.76  ? 191 VAL C CA    1 
ATOM   4321 C C     . VAL B 2 188 ? 268.814 156.665 215.797 1.00 76.76  ? 191 VAL C C     1 
ATOM   4322 O O     . VAL B 2 188 ? 269.781 157.007 216.497 1.00 76.76  ? 191 VAL C O     1 
ATOM   4323 C CB    . VAL B 2 188 ? 267.887 158.116 213.937 1.00 76.76  ? 191 VAL C CB    1 
ATOM   4324 C CG1   . VAL B 2 188 ? 268.237 159.323 214.779 1.00 76.76  ? 191 VAL C CG1   1 
ATOM   4325 C CG2   . VAL B 2 188 ? 268.020 158.459 212.469 1.00 76.76  ? 191 VAL C CG2   1 
ATOM   4326 N N     . ILE B 2 189 ? 267.753 156.039 216.314 1.00 78.24  ? 192 ILE C N     1 
ATOM   4327 C CA    . ILE B 2 189 ? 267.712 155.720 217.738 1.00 78.24  ? 192 ILE C CA    1 
ATOM   4328 C C     . ILE B 2 189 ? 268.836 154.758 218.103 1.00 78.24  ? 192 ILE C C     1 
ATOM   4329 O O     . ILE B 2 189 ? 269.452 154.878 219.169 1.00 78.24  ? 192 ILE C O     1 
ATOM   4330 C CB    . ILE B 2 189 ? 266.332 155.158 218.121 1.00 78.24  ? 192 ILE C CB    1 
ATOM   4331 C CG1   . ILE B 2 189 ? 265.240 156.181 217.822 1.00 78.24  ? 192 ILE C CG1   1 
ATOM   4332 C CG2   . ILE B 2 189 ? 266.296 154.783 219.590 1.00 78.24  ? 192 ILE C CG2   1 
ATOM   4333 C CD1   . ILE B 2 189 ? 265.465 157.509 218.485 1.00 78.24  ? 192 ILE C CD1   1 
ATOM   4334 N N     . GLN B 2 190 ? 269.138 153.803 217.220 1.00 80.96  ? 193 GLN C N     1 
ATOM   4335 C CA    . GLN B 2 190 ? 270.196 152.838 217.500 1.00 80.96  ? 193 GLN C CA    1 
ATOM   4336 C C     . GLN B 2 190 ? 271.565 153.506 217.525 1.00 80.96  ? 193 GLN C C     1 
ATOM   4337 O O     . GLN B 2 190 ? 272.401 153.184 218.373 1.00 80.96  ? 193 GLN C O     1 
ATOM   4338 C CB    . GLN B 2 190 ? 270.161 151.716 216.465 1.00 80.96  ? 193 GLN C CB    1 
ATOM   4339 C CG    . GLN B 2 190 ? 271.076 150.545 216.770 1.00 80.96  ? 193 GLN C CG    1 
ATOM   4340 C CD    . GLN B 2 190 ? 272.476 150.736 216.225 1.00 80.96  ? 193 GLN C CD    1 
ATOM   4341 O OE1   . GLN B 2 190 ? 272.674 151.408 215.212 1.00 80.96  ? 193 GLN C OE1   1 
ATOM   4342 N NE2   . GLN B 2 190 ? 273.458 150.145 216.895 1.00 80.96  ? 193 GLN C NE2   1 
ATOM   4343 N N     . TYR B 2 191 ? 271.819 154.427 216.595 1.00 78.95  ? 194 TYR C N     1 
ATOM   4344 C CA    . TYR B 2 191 ? 273.079 155.160 216.608 1.00 78.95  ? 194 TYR C CA    1 
ATOM   4345 C C     . TYR B 2 191 ? 273.219 155.977 217.883 1.00 78.95  ? 194 TYR C C     1 
ATOM   4346 O O     . TYR B 2 191 ? 274.302 156.035 218.479 1.00 78.95  ? 194 TYR C O     1 
ATOM   4347 C CB    . TYR B 2 191 ? 273.170 156.062 215.380 1.00 78.95  ? 194 TYR C CB    1 
ATOM   4348 C CG    . TYR B 2 191 ? 274.410 156.925 215.325 1.00 78.95  ? 194 TYR C CG    1 
ATOM   4349 C CD1   . TYR B 2 191 ? 274.395 158.228 215.795 1.00 78.95  ? 194 TYR C CD1   1 
ATOM   4350 C CD2   . TYR B 2 191 ? 275.592 156.439 214.791 1.00 78.95  ? 194 TYR C CD2   1 
ATOM   4351 C CE1   . TYR B 2 191 ? 275.522 159.017 215.741 1.00 78.95  ? 194 TYR C CE1   1 
ATOM   4352 C CE2   . TYR B 2 191 ? 276.721 157.222 214.733 1.00 78.95  ? 194 TYR C CE2   1 
ATOM   4353 C CZ    . TYR B 2 191 ? 276.681 158.509 215.206 1.00 78.95  ? 194 TYR C CZ    1 
ATOM   4354 O OH    . TYR B 2 191 ? 277.810 159.289 215.149 1.00 78.95  ? 194 TYR C OH    1 
ATOM   4355 N N     . PHE B 2 192 ? 272.132 156.620 218.315 1.00 79.10  ? 195 PHE C N     1 
ATOM   4356 C CA    . PHE B 2 192 ? 272.187 157.384 219.557 1.00 79.10  ? 195 PHE C CA    1 
ATOM   4357 C C     . PHE B 2 192 ? 272.446 156.478 220.753 1.00 79.10  ? 195 PHE C C     1 
ATOM   4358 O O     . PHE B 2 192 ? 273.188 156.844 221.671 1.00 79.10  ? 195 PHE C O     1 
ATOM   4359 C CB    . PHE B 2 192 ? 270.895 158.169 219.743 1.00 79.10  ? 195 PHE C CB    1 
ATOM   4360 C CG    . PHE B 2 192 ? 270.878 159.464 219.004 1.00 79.10  ? 195 PHE C CG    1 
ATOM   4361 C CD1   . PHE B 2 192 ? 272.037 160.197 218.859 1.00 79.10  ? 195 PHE C CD1   1 
ATOM   4362 C CD2   . PHE B 2 192 ? 269.716 159.938 218.429 1.00 79.10  ? 195 PHE C CD2   1 
ATOM   4363 C CE1   . PHE B 2 192 ? 272.032 161.386 218.175 1.00 79.10  ? 195 PHE C CE1   1 
ATOM   4364 C CE2   . PHE B 2 192 ? 269.705 161.124 217.745 1.00 79.10  ? 195 PHE C CE2   1 
ATOM   4365 C CZ    . PHE B 2 192 ? 270.864 161.850 217.616 1.00 79.10  ? 195 PHE C CZ    1 
ATOM   4366 N N     . ALA B 2 193 ? 271.844 155.290 220.760 1.00 80.80  ? 196 ALA C N     1 
ATOM   4367 C CA    . ALA B 2 193 ? 272.111 154.337 221.831 1.00 80.80  ? 196 ALA C CA    1 
ATOM   4368 C C     . ALA B 2 193 ? 273.557 153.864 221.799 1.00 80.80  ? 196 ALA C C     1 
ATOM   4369 O O     . ALA B 2 193 ? 274.169 153.642 222.849 1.00 80.80  ? 196 ALA C O     1 
ATOM   4370 C CB    . ALA B 2 193 ? 271.157 153.149 221.728 1.00 80.80  ? 196 ALA C CB    1 
ATOM   4371 N N     . SER B 2 194 ? 274.121 153.709 220.602 1.00 81.66  ? 197 SER C N     1 
ATOM   4372 C CA    . SER B 2 194 ? 275.461 153.149 220.475 1.00 81.66  ? 197 SER C CA    1 
ATOM   4373 C C     . SER B 2 194 ? 276.529 154.151 220.894 1.00 81.66  ? 197 SER C C     1 
ATOM   4374 O O     . SER B 2 194 ? 277.466 153.801 221.619 1.00 81.66  ? 197 SER C O     1 
ATOM   4375 C CB    . SER B 2 194 ? 275.697 152.682 219.040 1.00 81.66  ? 197 SER C CB    1 
ATOM   4376 O OG    . SER B 2 194 ? 277.081 152.607 218.755 1.00 81.66  ? 197 SER C OG    1 
ATOM   4377 N N     . ILE B 2 195 ? 276.417 155.401 220.442 1.00 81.81  ? 198 ILE C N     1 
ATOM   4378 C CA    . ILE B 2 195 ? 277.479 156.367 220.718 1.00 81.81  ? 198 ILE C CA    1 
ATOM   4379 C C     . ILE B 2 195 ? 277.513 156.719 222.203 1.00 81.81  ? 198 ILE C C     1 
ATOM   4380 O O     . ILE B 2 195 ? 278.557 156.617 222.855 1.00 81.81  ? 198 ILE C O     1 
ATOM   4381 C CB    . ILE B 2 195 ? 277.340 157.614 219.823 1.00 81.81  ? 198 ILE C CB    1 
ATOM   4382 C CG1   . ILE B 2 195 ? 276.029 158.365 220.069 1.00 81.81  ? 198 ILE C CG1   1 
ATOM   4383 C CG2   . ILE B 2 195 ? 277.447 157.221 218.362 1.00 81.81  ? 198 ILE C CG2   1 
ATOM   4384 C CD1   . ILE B 2 195 ? 275.964 159.715 219.397 1.00 81.81  ? 198 ILE C CD1   1 
ATOM   4385 N N     . ALA B 2 196 ? 276.381 157.136 222.758 1.00 84.06  ? 199 ALA C N     1 
ATOM   4386 C CA    . ALA B 2 196 ? 276.287 157.450 224.183 1.00 84.06  ? 199 ALA C CA    1 
ATOM   4387 C C     . ALA B 2 196 ? 275.730 156.258 224.959 1.00 84.06  ? 199 ALA C C     1 
ATOM   4388 O O     . ALA B 2 196 ? 274.720 156.346 225.655 1.00 84.06  ? 199 ALA C O     1 
ATOM   4389 C CB    . ALA B 2 196 ? 275.438 158.698 224.392 1.00 84.06  ? 199 ALA C CB    1 
ATOM   4390 N N     . ALA B 2 197 ? 276.418 155.128 224.839 1.00 86.11  ? 200 ALA C N     1 
ATOM   4391 C CA    . ALA B 2 197 ? 275.987 153.902 225.499 1.00 86.11  ? 200 ALA C CA    1 
ATOM   4392 C C     . ALA B 2 197 ? 276.245 153.967 226.999 1.00 86.11  ? 200 ALA C C     1 
ATOM   4393 O O     . ALA B 2 197 ? 276.662 152.984 227.611 1.00 86.11  ? 200 ALA C O     1 
ATOM   4394 C CB    . ALA B 2 197 ? 276.689 152.700 224.892 1.00 86.11  ? 200 ALA C CB    1 
ATOM   4395 N N     . GLY B 2 212 ? 265.755 144.569 226.451 1.00 93.03  ? 215 GLY C N     1 
ATOM   4396 C CA    . GLY B 2 212 ? 265.590 145.655 227.399 1.00 93.03  ? 215 GLY C CA    1 
ATOM   4397 C C     . GLY B 2 212 ? 266.220 146.954 226.939 1.00 93.03  ? 215 GLY C C     1 
ATOM   4398 O O     . GLY B 2 212 ? 266.068 147.989 227.587 1.00 93.03  ? 215 GLY C O     1 
ATOM   4399 N N     . THR B 2 213 ? 266.931 146.899 225.816 1.00 93.27  ? 216 THR C N     1 
ATOM   4400 C CA    . THR B 2 213 ? 267.578 148.085 225.277 1.00 93.27  ? 216 THR C CA    1 
ATOM   4401 C C     . THR B 2 213 ? 266.536 149.086 224.785 1.00 93.27  ? 216 THR C C     1 
ATOM   4402 O O     . THR B 2 213 ? 265.396 148.735 224.473 1.00 93.27  ? 216 THR C O     1 
ATOM   4403 C CB    . THR B 2 213 ? 268.524 147.710 224.137 1.00 93.27  ? 216 THR C CB    1 
ATOM   4404 O OG1   . THR B 2 213 ? 267.780 147.095 223.078 1.00 93.27  ? 216 THR C OG1   1 
ATOM   4405 C CG2   . THR B 2 213 ? 269.585 146.740 224.629 1.00 93.27  ? 216 THR C CG2   1 
ATOM   4406 N N     . LEU B 2 214 ? 266.949 150.354 224.717 1.00 90.23  ? 217 LEU C N     1 
ATOM   4407 C CA    . LEU B 2 214 ? 266.014 151.424 224.385 1.00 90.23  ? 217 LEU C CA    1 
ATOM   4408 C C     . LEU B 2 214 ? 265.361 151.210 223.027 1.00 90.23  ? 217 LEU C C     1 
ATOM   4409 O O     . LEU B 2 214 ? 264.151 151.415 222.882 1.00 90.23  ? 217 LEU C O     1 
ATOM   4410 C CB    . LEU B 2 214 ? 266.732 152.771 224.415 1.00 90.23  ? 217 LEU C CB    1 
ATOM   4411 C CG    . LEU B 2 214 ? 265.832 153.986 224.221 1.00 90.23  ? 217 LEU C CG    1 
ATOM   4412 C CD1   . LEU B 2 214 ? 264.836 154.042 225.360 1.00 90.23  ? 217 LEU C CD1   1 
ATOM   4413 C CD2   . LEU B 2 214 ? 266.655 155.259 224.158 1.00 90.23  ? 217 LEU C CD2   1 
ATOM   4414 N N     . GLU B 2 215 ? 266.143 150.803 222.027 1.00 90.77  ? 218 GLU C N     1 
ATOM   4415 C CA    . GLU B 2 215 ? 265.598 150.540 220.700 1.00 90.77  ? 218 GLU C CA    1 
ATOM   4416 C C     . GLU B 2 215 ? 264.516 149.469 220.760 1.00 90.77  ? 218 GLU C C     1 
ATOM   4417 O O     . GLU B 2 215 ? 263.405 149.653 220.246 1.00 90.77  ? 218 GLU C O     1 
ATOM   4418 C CB    . GLU B 2 215 ? 266.729 150.124 219.759 1.00 90.77  ? 218 GLU C CB    1 
ATOM   4419 C CG    . GLU B 2 215 ? 266.284 149.632 218.397 1.00 90.77  ? 218 GLU C CG    1 
ATOM   4420 C CD    . GLU B 2 215 ? 267.375 148.853 217.686 1.00 90.77  ? 218 GLU C CD    1 
ATOM   4421 O OE1   . GLU B 2 215 ? 267.695 147.733 218.136 1.00 90.77  ? 218 GLU C OE1   1 
ATOM   4422 O OE2   . GLU B 2 215 ? 267.920 149.361 216.684 1.00 90.77  ? 218 GLU C OE2   1 
ATOM   4423 N N     . ASP B 2 216 ? 264.829 148.337 221.391 1.00 91.38  ? 219 ASP C N     1 
ATOM   4424 C CA    . ASP B 2 216 ? 263.858 147.256 221.504 1.00 91.38  ? 219 ASP C CA    1 
ATOM   4425 C C     . ASP B 2 216 ? 262.644 147.688 222.317 1.00 91.38  ? 219 ASP C C     1 
ATOM   4426 O O     . ASP B 2 216 ? 261.523 147.245 222.052 1.00 91.38  ? 219 ASP C O     1 
ATOM   4427 C CB    . ASP B 2 216 ? 264.520 146.029 222.128 1.00 91.38  ? 219 ASP C CB    1 
ATOM   4428 C CG    . ASP B 2 216 ? 263.536 144.917 222.409 1.00 91.38  ? 219 ASP C CG    1 
ATOM   4429 O OD1   . ASP B 2 216 ? 263.421 144.507 223.583 1.00 91.38  ? 219 ASP C OD1   1 
ATOM   4430 O OD2   . ASP B 2 216 ? 262.880 144.449 221.456 1.00 91.38  ? 219 ASP C OD2   1 
ATOM   4431 N N     . GLN B 2 217 ? 262.845 148.559 223.308 1.00 89.78  ? 220 GLN C N     1 
ATOM   4432 C CA    . GLN B 2 217 ? 261.718 149.053 224.092 1.00 89.78  ? 220 GLN C CA    1 
ATOM   4433 C C     . GLN B 2 217 ? 260.773 149.881 223.235 1.00 89.78  ? 220 GLN C C     1 
ATOM   4434 O O     . GLN B 2 217 ? 259.555 149.680 223.268 1.00 89.78  ? 220 GLN C O     1 
ATOM   4435 C CB    . GLN B 2 217 ? 262.217 149.881 225.275 1.00 89.78  ? 220 GLN C CB    1 
ATOM   4436 C CG    . GLN B 2 217 ? 262.890 149.082 226.369 1.00 89.78  ? 220 GLN C CG    1 
ATOM   4437 C CD    . GLN B 2 217 ? 263.741 149.952 227.266 1.00 89.78  ? 220 GLN C CD    1 
ATOM   4438 O OE1   . GLN B 2 217 ? 263.938 151.135 226.994 1.00 89.78  ? 220 GLN C OE1   1 
ATOM   4439 N NE2   . GLN B 2 217 ? 264.258 149.369 228.339 1.00 89.78  ? 220 GLN C NE2   1 
ATOM   4440 N N     . ILE B 2 218 ? 261.317 150.827 222.466 1.00 85.58  ? 221 ILE C N     1 
ATOM   4441 C CA    . ILE B 2 218 ? 260.475 151.655 221.611 1.00 85.58  ? 221 ILE C CA    1 
ATOM   4442 C C     . ILE B 2 218 ? 259.818 150.814 220.524 1.00 85.58  ? 221 ILE C C     1 
ATOM   4443 O O     . ILE B 2 218 ? 258.715 151.132 220.065 1.00 85.58  ? 221 ILE C O     1 
ATOM   4444 C CB    . ILE B 2 218 ? 261.299 152.815 221.022 1.00 85.58  ? 221 ILE C CB    1 
ATOM   4445 C CG1   . ILE B 2 218 ? 261.977 153.599 222.143 1.00 85.58  ? 221 ILE C CG1   1 
ATOM   4446 C CG2   . ILE B 2 218 ? 260.420 153.747 220.214 1.00 85.58  ? 221 ILE C CG2   1 
ATOM   4447 C CD1   . ILE B 2 218 ? 262.672 154.852 221.680 1.00 85.58  ? 221 ILE C CD1   1 
ATOM   4448 N N     . ILE B 2 219 ? 260.464 149.724 220.105 1.00 87.25  ? 222 ILE C N     1 
ATOM   4449 C CA    . ILE B 2 219 ? 259.867 148.863 219.088 1.00 87.25  ? 222 ILE C CA    1 
ATOM   4450 C C     . ILE B 2 219 ? 258.808 147.933 219.673 1.00 87.25  ? 222 ILE C C     1 
ATOM   4451 O O     . ILE B 2 219 ? 257.890 147.519 218.955 1.00 87.25  ? 222 ILE C O     1 
ATOM   4452 C CB    . ILE B 2 219 ? 260.980 148.080 218.367 1.00 87.25  ? 222 ILE C CB    1 
ATOM   4453 C CG1   . ILE B 2 219 ? 261.835 149.032 217.533 1.00 87.25  ? 222 ILE C CG1   1 
ATOM   4454 C CG2   . ILE B 2 219 ? 260.419 146.993 217.466 1.00 87.25  ? 222 ILE C CG2   1 
ATOM   4455 C CD1   . ILE B 2 219 ? 261.030 149.974 216.667 1.00 87.25  ? 222 ILE C CD1   1 
ATOM   4456 N N     . GLN B 2 220 ? 258.881 147.628 220.969 1.00 87.29  ? 223 GLN C N     1 
ATOM   4457 C CA    . GLN B 2 220 ? 257.931 146.699 221.573 1.00 87.29  ? 223 GLN C CA    1 
ATOM   4458 C C     . GLN B 2 220 ? 256.524 147.283 221.605 1.00 87.29  ? 223 GLN C C     1 
ATOM   4459 O O     . GLN B 2 220 ? 255.541 146.576 221.354 1.00 87.29  ? 223 GLN C O     1 
ATOM   4460 C CB    . GLN B 2 220 ? 258.387 146.333 222.984 1.00 87.29  ? 223 GLN C CB    1 
ATOM   4461 C CG    . GLN B 2 220 ? 259.318 145.138 223.060 1.00 87.29  ? 223 GLN C CG    1 
ATOM   4462 C CD    . GLN B 2 220 ? 259.783 144.862 224.475 1.00 87.29  ? 223 GLN C CD    1 
ATOM   4463 O OE1   . GLN B 2 220 ? 260.439 143.856 224.742 1.00 87.29  ? 223 GLN C OE1   1 
ATOM   4464 N NE2   . GLN B 2 220 ? 259.446 145.759 225.392 1.00 87.29  ? 223 GLN C NE2   1 
ATOM   4465 N N     . ALA B 2 221 ? 256.407 148.568 221.921 1.00 83.00  ? 224 ALA C N     1 
ATOM   4466 C CA    . ALA B 2 221 ? 255.115 149.231 222.039 1.00 83.00  ? 224 ALA C CA    1 
ATOM   4467 C C     . ALA B 2 221 ? 254.536 149.658 220.698 1.00 83.00  ? 224 ALA C C     1 
ATOM   4468 O O     . ALA B 2 221 ? 253.577 150.435 220.674 1.00 83.00  ? 224 ALA C O     1 
ATOM   4469 C CB    . ALA B 2 221 ? 255.235 150.449 222.958 1.00 83.00  ? 224 ALA C CB    1 
ATOM   4470 N N     . ASN B 2 222 ? 255.086 149.178 219.595 1.00 81.81  ? 225 ASN C N     1 
ATOM   4471 C CA    . ASN B 2 222 ? 254.675 149.640 218.276 1.00 81.81  ? 225 ASN C CA    1 
ATOM   4472 C C     . ASN B 2 222 ? 253.341 149.051 217.817 1.00 81.81  ? 225 ASN C C     1 
ATOM   4473 O O     . ASN B 2 222 ? 252.512 149.798 217.284 1.00 81.81  ? 225 ASN C O     1 
ATOM   4474 C CB    . ASN B 2 222 ? 255.766 149.335 217.249 1.00 81.81  ? 225 ASN C CB    1 
ATOM   4475 C CG    . ASN B 2 222 ? 255.671 150.214 216.029 1.00 81.81  ? 225 ASN C CG    1 
ATOM   4476 O OD1   . ASN B 2 222 ? 255.457 151.420 216.138 1.00 81.81  ? 225 ASN C OD1   1 
ATOM   4477 N ND2   . ASN B 2 222 ? 255.822 149.616 214.854 1.00 81.81  ? 225 ASN C ND2   1 
ATOM   4478 N N     . PRO B 2 223 ? 253.090 147.743 217.973 1.00 81.63  ? 226 PRO C N     1 
ATOM   4479 C CA    . PRO B 2 223 ? 251.823 147.192 217.458 1.00 81.63  ? 226 PRO C CA    1 
ATOM   4480 C C     . PRO B 2 223 ? 250.573 147.834 218.038 1.00 81.63  ? 226 PRO C C     1 
ATOM   4481 O O     . PRO B 2 223 ? 249.563 147.928 217.333 1.00 81.63  ? 226 PRO C O     1 
ATOM   4482 C CB    . PRO B 2 223 ? 251.918 145.708 217.832 1.00 81.63  ? 226 PRO C CB    1 
ATOM   4483 C CG    . PRO B 2 223 ? 253.360 145.430 217.819 1.00 81.63  ? 226 PRO C CG    1 
ATOM   4484 C CD    . PRO B 2 223 ? 253.995 146.658 218.400 1.00 81.63  ? 226 PRO C CD    1 
ATOM   4485 N N     . ALA B 2 224 ? 250.603 148.294 219.289 1.00 76.34  ? 227 ALA C N     1 
ATOM   4486 C CA    . ALA B 2 224 ? 249.423 148.936 219.861 1.00 76.34  ? 227 ALA C CA    1 
ATOM   4487 C C     . ALA B 2 224 ? 249.149 150.279 219.193 1.00 76.34  ? 227 ALA C C     1 
ATOM   4488 O O     . ALA B 2 224 ? 248.014 150.562 218.779 1.00 76.34  ? 227 ALA C O     1 
ATOM   4489 C CB    . ALA B 2 224 ? 249.599 149.108 221.367 1.00 76.34  ? 227 ALA C CB    1 
ATOM   4490 N N     . LEU B 2 225 ? 250.176 151.125 219.086 1.00 74.55  ? 228 LEU C N     1 
ATOM   4491 C CA    . LEU B 2 225 ? 250.005 152.399 218.399 1.00 74.55  ? 228 LEU C CA    1 
ATOM   4492 C C     . LEU B 2 225 ? 249.652 152.200 216.936 1.00 74.55  ? 228 LEU C C     1 
ATOM   4493 O O     . LEU B 2 225 ? 248.984 153.050 216.342 1.00 74.55  ? 228 LEU C O     1 
ATOM   4494 C CB    . LEU B 2 225 ? 251.265 153.249 218.515 1.00 74.55  ? 228 LEU C CB    1 
ATOM   4495 C CG    . LEU B 2 225 ? 251.614 153.802 219.891 1.00 74.55  ? 228 LEU C CG    1 
ATOM   4496 C CD1   . LEU B 2 225 ? 252.925 154.543 219.800 1.00 74.55  ? 228 LEU C CD1   1 
ATOM   4497 C CD2   . LEU B 2 225 ? 250.516 154.716 220.389 1.00 74.55  ? 228 LEU C CD2   1 
ATOM   4498 N N     . GLU B 2 226 ? 250.080 151.089 216.337 1.00 76.91  ? 229 GLU C N     1 
ATOM   4499 C CA    . GLU B 2 226 ? 249.658 150.794 214.974 1.00 76.91  ? 229 GLU C CA    1 
ATOM   4500 C C     . GLU B 2 226 ? 248.172 150.462 214.929 1.00 76.91  ? 229 GLU C C     1 
ATOM   4501 O O     . GLU B 2 226 ? 247.406 151.096 214.197 1.00 76.91  ? 229 GLU C O     1 
ATOM   4502 C CB    . GLU B 2 226 ? 250.490 149.650 214.397 1.00 76.91  ? 229 GLU C CB    1 
ATOM   4503 C CG    . GLU B 2 226 ? 251.940 150.019 214.140 1.00 76.91  ? 229 GLU C CG    1 
ATOM   4504 C CD    . GLU B 2 226 ? 252.571 149.199 213.029 1.00 76.91  ? 229 GLU C CD    1 
ATOM   4505 O OE1   . GLU B 2 226 ? 252.067 149.253 211.888 1.00 76.91  ? 229 GLU C OE1   1 
ATOM   4506 O OE2   . GLU B 2 226 ? 253.573 148.504 213.295 1.00 76.91  ? 229 GLU C OE2   1 
ATOM   4507 N N     . ALA B 2 227 ? 247.740 149.488 215.729 1.00 71.28  ? 230 ALA C N     1 
ATOM   4508 C CA    . ALA B 2 227 ? 246.343 149.080 215.717 1.00 71.28  ? 230 ALA C CA    1 
ATOM   4509 C C     . ALA B 2 227 ? 245.399 150.218 216.070 1.00 71.28  ? 230 ALA C C     1 
ATOM   4510 O O     . ALA B 2 227 ? 244.239 150.190 215.650 1.00 71.28  ? 230 ALA C O     1 
ATOM   4511 C CB    . ALA B 2 227 ? 246.124 147.914 216.680 1.00 71.28  ? 230 ALA C CB    1 
ATOM   4512 N N     . PHE B 2 228 ? 245.860 151.217 216.819 1.00 69.09  ? 231 PHE C N     1 
ATOM   4513 C CA    . PHE B 2 228 ? 244.969 152.303 217.206 1.00 69.09  ? 231 PHE C CA    1 
ATOM   4514 C C     . PHE B 2 228 ? 245.199 153.606 216.452 1.00 69.09  ? 231 PHE C C     1 
ATOM   4515 O O     . PHE B 2 228 ? 244.382 154.522 216.582 1.00 69.09  ? 231 PHE C O     1 
ATOM   4516 C CB    . PHE B 2 228 ? 245.077 152.561 218.711 1.00 69.09  ? 231 PHE C CB    1 
ATOM   4517 C CG    . PHE B 2 228 ? 244.334 151.562 219.533 1.00 69.09  ? 231 PHE C CG    1 
ATOM   4518 C CD1   . PHE B 2 228 ? 244.898 150.338 219.831 1.00 69.09  ? 231 PHE C CD1   1 
ATOM   4519 C CD2   . PHE B 2 228 ? 243.062 151.836 219.990 1.00 69.09  ? 231 PHE C CD2   1 
ATOM   4520 C CE1   . PHE B 2 228 ? 244.211 149.411 220.575 1.00 69.09  ? 231 PHE C CE1   1 
ATOM   4521 C CE2   . PHE B 2 228 ? 242.372 150.912 220.737 1.00 69.09  ? 231 PHE C CE2   1 
ATOM   4522 C CZ    . PHE B 2 228 ? 242.948 149.698 221.027 1.00 69.09  ? 231 PHE C CZ    1 
ATOM   4523 N N     . GLY B 2 229 ? 246.273 153.723 215.676 1.00 68.41  ? 232 GLY C N     1 
ATOM   4524 C CA    . GLY B 2 229 ? 246.523 154.955 214.956 1.00 68.41  ? 232 GLY C CA    1 
ATOM   4525 C C     . GLY B 2 229 ? 246.907 154.777 213.502 1.00 68.41  ? 232 GLY C C     1 
ATOM   4526 O O     . GLY B 2 229 ? 247.347 155.731 212.857 1.00 68.41  ? 232 GLY C O     1 
ATOM   4527 N N     . ASN B 2 230 ? 246.745 153.569 212.970 1.00 71.14  ? 233 ASN C N     1 
ATOM   4528 C CA    . ASN B 2 230 ? 247.051 153.284 211.576 1.00 71.14  ? 233 ASN C CA    1 
ATOM   4529 C C     . ASN B 2 230 ? 245.768 152.951 210.835 1.00 71.14  ? 233 ASN C C     1 
ATOM   4530 O O     . ASN B 2 230 ? 244.950 152.162 211.315 1.00 71.14  ? 233 ASN C O     1 
ATOM   4531 C CB    . ASN B 2 230 ? 248.039 152.125 211.434 1.00 71.14  ? 233 ASN C CB    1 
ATOM   4532 C CG    . ASN B 2 230 ? 249.477 152.587 211.392 1.00 71.14  ? 233 ASN C CG    1 
ATOM   4533 O OD1   . ASN B 2 230 ? 249.770 153.701 210.975 1.00 71.14  ? 233 ASN C OD1   1 
ATOM   4534 N ND2   . ASN B 2 230 ? 250.386 151.724 211.816 1.00 71.14  ? 233 ASN C ND2   1 
ATOM   4535 N N     . ALA B 2 231 ? 245.600 153.551 209.662 1.00 74.17  ? 234 ALA C N     1 
ATOM   4536 C CA    . ALA B 2 231 ? 244.401 153.356 208.866 1.00 74.17  ? 234 ALA C CA    1 
ATOM   4537 C C     . ALA B 2 231 ? 244.778 153.181 207.406 1.00 74.17  ? 234 ALA C C     1 
ATOM   4538 O O     . ALA B 2 231 ? 245.730 153.793 206.916 1.00 74.17  ? 234 ALA C O     1 
ATOM   4539 C CB    . ALA B 2 231 ? 243.436 154.530 209.014 1.00 74.17  ? 234 ALA C CB    1 
ATOM   4540 N N     . LYS B 2 232 ? 244.014 152.343 206.715 1.00 79.48  ? 235 LYS C N     1 
ATOM   4541 C CA    . LYS B 2 232 ? 244.243 152.069 205.299 1.00 79.48  ? 235 LYS C CA    1 
ATOM   4542 C C     . LYS B 2 232 ? 243.761 153.256 204.477 1.00 79.48  ? 235 LYS C C     1 
ATOM   4543 O O     . LYS B 2 232 ? 242.569 153.396 204.202 1.00 79.48  ? 235 LYS C O     1 
ATOM   4544 C CB    . LYS B 2 232 ? 243.533 150.783 204.889 1.00 79.48  ? 235 LYS C CB    1 
ATOM   4545 C CG    . LYS B 2 232 ? 243.877 150.291 203.489 1.00 79.48  ? 235 LYS C CG    1 
ATOM   4546 C CD    . LYS B 2 232 ? 242.888 150.797 202.454 1.00 79.48  ? 235 LYS C CD    1 
ATOM   4547 C CE    . LYS B 2 232 ? 243.221 150.294 201.066 1.00 79.48  ? 235 LYS C CE    1 
ATOM   4548 N NZ    . LYS B 2 232 ? 242.277 150.850 200.060 1.00 79.48  ? 235 LYS C NZ    1 
ATOM   4549 N N     . THR B 2 233 ? 244.686 154.125 204.087 1.00 80.61  ? 236 THR C N     1 
ATOM   4550 C CA    . THR B 2 233 ? 244.373 155.187 203.147 1.00 80.61  ? 236 THR C CA    1 
ATOM   4551 C C     . THR B 2 233 ? 244.293 154.601 201.737 1.00 80.61  ? 236 THR C C     1 
ATOM   4552 O O     . THR B 2 233 ? 244.545 153.414 201.521 1.00 80.61  ? 236 THR C O     1 
ATOM   4553 C CB    . THR B 2 233 ? 245.430 156.294 203.230 1.00 80.61  ? 236 THR C CB    1 
ATOM   4554 O OG1   . THR B 2 233 ? 245.760 156.523 204.603 1.00 80.61  ? 236 THR C OG1   1 
ATOM   4555 C CG2   . THR B 2 233 ? 244.903 157.601 202.666 1.00 80.61  ? 236 THR C CG2   1 
ATOM   4556 N N     . VAL B 2 234 ? 243.920 155.441 200.770 1.00 83.15  ? 237 VAL C N     1 
ATOM   4557 C CA    . VAL B 2 234 ? 243.813 154.955 199.398 1.00 83.15  ? 237 VAL C CA    1 
ATOM   4558 C C     . VAL B 2 234 ? 245.191 154.800 198.763 1.00 83.15  ? 237 VAL C C     1 
ATOM   4559 O O     . VAL B 2 234 ? 245.421 153.862 197.991 1.00 83.15  ? 237 VAL C O     1 
ATOM   4560 C CB    . VAL B 2 234 ? 242.900 155.880 198.571 1.00 83.15  ? 237 VAL C CB    1 
ATOM   4561 C CG1   . VAL B 2 234 ? 243.440 157.300 198.550 1.00 83.15  ? 237 VAL C CG1   1 
ATOM   4562 C CG2   . VAL B 2 234 ? 242.732 155.337 197.161 1.00 83.15  ? 237 VAL C CG2   1 
ATOM   4563 N N     . ARG B 2 235 ? 246.133 155.689 199.082 1.00 82.66  ? 238 ARG C N     1 
ATOM   4564 C CA    . ARG B 2 235 ? 247.478 155.631 198.526 1.00 82.66  ? 238 ARG C CA    1 
ATOM   4565 C C     . ARG B 2 235 ? 248.458 154.953 199.486 1.00 82.66  ? 238 ARG C C     1 
ATOM   4566 O O     . ARG B 2 235 ? 249.645 155.295 199.523 1.00 82.66  ? 238 ARG C O     1 
ATOM   4567 C CB    . ARG B 2 235 ? 247.951 157.039 198.151 1.00 82.66  ? 238 ARG C CB    1 
ATOM   4568 C CG    . ARG B 2 235 ? 249.205 157.081 197.282 1.00 82.66  ? 238 ARG C CG    1 
ATOM   4569 C CD    . ARG B 2 235 ? 249.642 158.498 196.934 1.00 82.66  ? 238 ARG C CD    1 
ATOM   4570 N NE    . ARG B 2 235 ? 248.745 159.161 195.994 1.00 82.66  ? 238 ARG C NE    1 
ATOM   4571 C CZ    . ARG B 2 235 ? 248.852 160.439 195.641 1.00 82.66  ? 238 ARG C CZ    1 
ATOM   4572 N NH1   . ARG B 2 235 ? 249.820 161.188 196.150 1.00 82.66  ? 238 ARG C NH1   1 
ATOM   4573 N NH2   . ARG B 2 235 ? 247.997 160.967 194.778 1.00 82.66  ? 238 ARG C NH2   1 
ATOM   4574 N N     . ASN B 2 236 ? 247.978 153.992 200.267 1.00 82.72  ? 239 ASN C N     1 
ATOM   4575 C CA    . ASN B 2 236 ? 248.809 153.278 201.230 1.00 82.72  ? 239 ASN C CA    1 
ATOM   4576 C C     . ASN B 2 236 ? 248.006 152.086 201.736 1.00 82.72  ? 239 ASN C C     1 
ATOM   4577 O O     . ASN B 2 236 ? 246.844 151.894 201.367 1.00 82.72  ? 239 ASN C O     1 
ATOM   4578 C CB    . ASN B 2 236 ? 249.245 154.197 202.376 1.00 82.72  ? 239 ASN C CB    1 
ATOM   4579 C CG    . ASN B 2 236 ? 250.409 153.637 203.168 1.00 82.72  ? 239 ASN C CG    1 
ATOM   4580 O OD1   . ASN B 2 236 ? 250.345 152.521 203.681 1.00 82.72  ? 239 ASN C OD1   1 
ATOM   4581 N ND2   . ASN B 2 236 ? 251.482 154.410 203.271 1.00 82.72  ? 239 ASN C ND2   1 
ATOM   4582 N N     . ASP B 2 237 ? 248.642 151.277 202.579 1.00 84.10  ? 240 ASP C N     1 
ATOM   4583 C CA    . ASP B 2 237 ? 247.965 150.207 203.294 1.00 84.10  ? 240 ASP C CA    1 
ATOM   4584 C C     . ASP B 2 237 ? 248.229 150.240 204.788 1.00 84.10  ? 240 ASP C C     1 
ATOM   4585 O O     . ASP B 2 237 ? 247.561 149.514 205.531 1.00 84.10  ? 240 ASP C O     1 
ATOM   4586 C CB    . ASP B 2 237 ? 248.383 148.834 202.745 1.00 84.10  ? 240 ASP C CB    1 
ATOM   4587 C CG    . ASP B 2 237 ? 247.827 148.563 201.364 1.00 84.10  ? 240 ASP C CG    1 
ATOM   4588 O OD1   . ASP B 2 237 ? 246.722 149.054 201.061 1.00 84.10  ? 240 ASP C OD1   1 
ATOM   4589 O OD2   . ASP B 2 237 ? 248.498 147.867 200.576 1.00 84.10  ? 240 ASP C OD2   1 
ATOM   4590 N N     . ASN B 2 238 ? 249.185 151.046 205.246 1.00 77.86  ? 241 ASN C N     1 
ATOM   4591 C CA    . ASN B 2 238 ? 249.488 151.203 206.667 1.00 77.86  ? 241 ASN C CA    1 
ATOM   4592 C C     . ASN B 2 238 ? 249.954 152.648 206.838 1.00 77.86  ? 241 ASN C C     1 
ATOM   4593 O O     . ASN B 2 238 ? 251.136 152.953 206.674 1.00 77.86  ? 241 ASN C O     1 
ATOM   4594 C CB    . ASN B 2 238 ? 250.548 150.211 207.116 1.00 77.86  ? 241 ASN C CB    1 
ATOM   4595 C CG    . ASN B 2 238 ? 250.327 149.718 208.523 1.00 77.86  ? 241 ASN C CG    1 
ATOM   4596 O OD1   . ASN B 2 238 ? 249.194 149.593 208.975 1.00 77.86  ? 241 ASN C OD1   1 
ATOM   4597 N ND2   . ASN B 2 238 ? 251.413 149.431 209.227 1.00 77.86  ? 241 ASN C ND2   1 
ATOM   4598 N N     . SER B 2 239 ? 249.017 153.528 207.171 1.00 73.81  ? 242 SER C N     1 
ATOM   4599 C CA    . SER B 2 239 ? 249.270 154.961 207.197 1.00 73.81  ? 242 SER C CA    1 
ATOM   4600 C C     . SER B 2 239 ? 249.141 155.480 208.619 1.00 73.81  ? 242 SER C C     1 
ATOM   4601 O O     . SER B 2 239 ? 248.121 155.254 209.277 1.00 73.81  ? 242 SER C O     1 
ATOM   4602 C CB    . SER B 2 239 ? 248.307 155.704 206.275 1.00 73.81  ? 242 SER C CB    1 
ATOM   4603 O OG    . SER B 2 239 ? 248.792 157.000 205.976 1.00 73.81  ? 242 SER C OG    1 
ATOM   4604 N N     . SER B 2 240 ? 250.171 156.180 209.084 1.00 69.95  ? 243 SER C N     1 
ATOM   4605 C CA    . SER B 2 240 ? 250.175 156.754 210.423 1.00 69.95  ? 243 SER C CA    1 
ATOM   4606 C C     . SER B 2 240 ? 249.417 158.072 210.385 1.00 69.95  ? 243 SER C C     1 
ATOM   4607 O O     . SER B 2 240 ? 249.885 159.050 209.794 1.00 69.95  ? 243 SER C O     1 
ATOM   4608 C CB    . SER B 2 240 ? 251.606 156.946 210.913 1.00 69.95  ? 243 SER C CB    1 
ATOM   4609 O OG    . SER B 2 240 ? 251.635 157.521 212.205 1.00 69.95  ? 243 SER C OG    1 
ATOM   4610 N N     . ARG B 2 241 ? 248.245 158.103 211.018 1.00 67.84  ? 244 ARG C N     1 
ATOM   4611 C CA    . ARG B 2 241 ? 247.353 159.254 210.971 1.00 67.84  ? 244 ARG C CA    1 
ATOM   4612 C C     . ARG B 2 241 ? 247.552 160.191 212.154 1.00 67.84  ? 244 ARG C C     1 
ATOM   4613 O O     . ARG B 2 241 ? 246.605 160.851 212.590 1.00 67.84  ? 244 ARG C O     1 
ATOM   4614 C CB    . ARG B 2 241 ? 245.902 158.788 210.898 1.00 67.84  ? 244 ARG C CB    1 
ATOM   4615 C CG    . ARG B 2 241 ? 245.626 157.824 209.761 1.00 67.84  ? 244 ARG C CG    1 
ATOM   4616 C CD    . ARG B 2 241 ? 245.180 158.556 208.511 1.00 67.84  ? 244 ARG C CD    1 
ATOM   4617 N NE    . ARG B 2 241 ? 246.273 159.277 207.870 1.00 67.84  ? 244 ARG C NE    1 
ATOM   4618 C CZ    . ARG B 2 241 ? 246.109 160.165 206.898 1.00 67.84  ? 244 ARG C CZ    1 
ATOM   4619 N NH1   . ARG B 2 241 ? 244.893 160.445 206.457 1.00 67.84  ? 244 ARG C NH1   1 
ATOM   4620 N NH2   . ARG B 2 241 ? 247.158 160.776 206.367 1.00 67.84  ? 244 ARG C NH2   1 
ATOM   4621 N N     . PHE B 2 242 ? 248.769 160.261 212.684 1.00 64.14  ? 245 PHE C N     1 
ATOM   4622 C CA    . PHE B 2 242 ? 249.093 161.170 213.771 1.00 64.14  ? 245 PHE C CA    1 
ATOM   4623 C C     . PHE B 2 242 ? 250.576 161.500 213.692 1.00 64.14  ? 245 PHE C C     1 
ATOM   4624 O O     . PHE B 2 242 ? 251.311 160.956 212.864 1.00 64.14  ? 245 PHE C O     1 
ATOM   4625 C CB    . PHE B 2 242 ? 248.720 160.571 215.131 1.00 64.14  ? 245 PHE C CB    1 
ATOM   4626 C CG    . PHE B 2 242 ? 249.406 159.270 215.436 1.00 64.14  ? 245 PHE C CG    1 
ATOM   4627 C CD1   . PHE B 2 242 ? 248.963 158.088 214.876 1.00 64.14  ? 245 PHE C CD1   1 
ATOM   4628 C CD2   . PHE B 2 242 ? 250.487 159.229 216.292 1.00 64.14  ? 245 PHE C CD2   1 
ATOM   4629 C CE1   . PHE B 2 242 ? 249.589 156.898 215.157 1.00 64.14  ? 245 PHE C CE1   1 
ATOM   4630 C CE2   . PHE B 2 242 ? 251.112 158.038 216.576 1.00 64.14  ? 245 PHE C CE2   1 
ATOM   4631 C CZ    . PHE B 2 242 ? 250.662 156.873 216.006 1.00 64.14  ? 245 PHE C CZ    1 
ATOM   4632 N N     . GLY B 2 243 ? 251.015 162.398 214.565 1.00 64.43  ? 246 GLY C N     1 
ATOM   4633 C CA    . GLY B 2 243 ? 252.411 162.778 214.600 1.00 64.43  ? 246 GLY C CA    1 
ATOM   4634 C C     . GLY B 2 243 ? 253.112 162.269 215.839 1.00 64.43  ? 246 GLY C C     1 
ATOM   4635 O O     . GLY B 2 243 ? 252.849 162.744 216.946 1.00 64.43  ? 246 GLY C O     1 
ATOM   4636 N N     . LYS B 2 244 ? 254.012 161.308 215.665 1.00 61.12  ? 247 LYS C N     1 
ATOM   4637 C CA    . LYS B 2 244 ? 254.714 160.679 216.773 1.00 61.12  ? 247 LYS C CA    1 
ATOM   4638 C C     . LYS B 2 244 ? 256.053 161.376 216.975 1.00 61.12  ? 247 LYS C C     1 
ATOM   4639 O O     . LYS B 2 244 ? 256.878 161.419 216.058 1.00 61.12  ? 247 LYS C O     1 
ATOM   4640 C CB    . LYS B 2 244 ? 254.912 159.189 216.509 1.00 61.12  ? 247 LYS C CB    1 
ATOM   4641 C CG    . LYS B 2 244 ? 255.713 158.480 217.573 1.00 61.12  ? 247 LYS C CG    1 
ATOM   4642 C CD    . LYS B 2 244 ? 256.134 157.103 217.114 1.00 61.12  ? 247 LYS C CD    1 
ATOM   4643 C CE    . LYS B 2 244 ? 254.950 156.170 217.009 1.00 61.12  ? 247 LYS C CE    1 
ATOM   4644 N NZ    . LYS B 2 244 ? 255.380 154.793 216.652 1.00 61.12  ? 247 LYS C NZ    1 
ATOM   4645 N N     . PHE B 2 245 ? 256.267 161.912 218.173 1.00 62.25  ? 248 PHE C N     1 
ATOM   4646 C CA    . PHE B 2 245 ? 257.462 162.679 218.517 1.00 62.25  ? 248 PHE C CA    1 
ATOM   4647 C C     . PHE B 2 245 ? 258.233 161.890 219.568 1.00 62.25  ? 248 PHE C C     1 
ATOM   4648 O O     . PHE B 2 245 ? 258.084 162.124 220.768 1.00 62.25  ? 248 PHE C O     1 
ATOM   4649 C CB    . PHE B 2 245 ? 257.082 164.065 219.024 1.00 62.25  ? 248 PHE C CB    1 
ATOM   4650 C CG    . PHE B 2 245 ? 258.225 165.036 219.076 1.00 62.25  ? 248 PHE C CG    1 
ATOM   4651 C CD1   . PHE B 2 245 ? 259.221 165.009 218.123 1.00 62.25  ? 248 PHE C CD1   1 
ATOM   4652 C CD2   . PHE B 2 245 ? 258.291 165.993 220.069 1.00 62.25  ? 248 PHE C CD2   1 
ATOM   4653 C CE1   . PHE B 2 245 ? 260.263 165.910 218.167 1.00 62.25  ? 248 PHE C CE1   1 
ATOM   4654 C CE2   . PHE B 2 245 ? 259.332 166.893 220.115 1.00 62.25  ? 248 PHE C CE2   1 
ATOM   4655 C CZ    . PHE B 2 245 ? 260.317 166.850 219.163 1.00 62.25  ? 248 PHE C CZ    1 
ATOM   4656 N N     . ILE B 2 246 ? 259.067 160.958 219.113 1.00 62.39  ? 249 ILE C N     1 
ATOM   4657 C CA    . ILE B 2 246 ? 259.877 160.171 220.034 1.00 62.39  ? 249 ILE C CA    1 
ATOM   4658 C C     . ILE B 2 246 ? 261.021 161.035 220.540 1.00 62.39  ? 249 ILE C C     1 
ATOM   4659 O O     . ILE B 2 246 ? 261.871 161.480 219.761 1.00 62.39  ? 249 ILE C O     1 
ATOM   4660 C CB    . ILE B 2 246 ? 260.405 158.900 219.360 1.00 62.39  ? 249 ILE C CB    1 
ATOM   4661 C CG1   . ILE B 2 246 ? 259.252 158.050 218.840 1.00 62.39  ? 249 ILE C CG1   1 
ATOM   4662 C CG2   . ILE B 2 246 ? 261.255 158.103 220.332 1.00 62.39  ? 249 ILE C CG2   1 
ATOM   4663 C CD1   . ILE B 2 246 ? 259.703 156.831 218.080 1.00 62.39  ? 249 ILE C CD1   1 
ATOM   4664 N N     . ARG B 2 247 ? 261.052 161.271 221.844 1.00 69.73  ? 250 ARG C N     1 
ATOM   4665 C CA    . ARG B 2 247 ? 262.102 162.061 222.472 1.00 69.73  ? 250 ARG C CA    1 
ATOM   4666 C C     . ARG B 2 247 ? 262.966 161.123 223.301 1.00 69.73  ? 250 ARG C C     1 
ATOM   4667 O O     . ARG B 2 247 ? 262.470 160.466 224.221 1.00 69.73  ? 250 ARG C O     1 
ATOM   4668 C CB    . ARG B 2 247 ? 261.517 163.162 223.348 1.00 69.73  ? 250 ARG C CB    1 
ATOM   4669 C CG    . ARG B 2 247 ? 260.420 163.970 222.693 1.00 69.73  ? 250 ARG C CG    1 
ATOM   4670 C CD    . ARG B 2 247 ? 260.025 165.145 223.557 1.00 69.73  ? 250 ARG C CD    1 
ATOM   4671 N NE    . ARG B 2 247 ? 259.718 164.729 224.917 1.00 69.73  ? 250 ARG C NE    1 
ATOM   4672 C CZ    . ARG B 2 247 ? 259.473 165.571 225.911 1.00 69.73  ? 250 ARG C CZ    1 
ATOM   4673 N NH1   . ARG B 2 247 ? 259.502 166.877 225.691 1.00 69.73  ? 250 ARG C NH1   1 
ATOM   4674 N NH2   . ARG B 2 247 ? 259.202 165.109 227.124 1.00 69.73  ? 250 ARG C NH2   1 
ATOM   4675 N N     . ILE B 2 248 ? 264.254 161.067 222.982 1.00 73.30  ? 251 ILE C N     1 
ATOM   4676 C CA    . ILE B 2 248 ? 265.220 160.309 223.761 1.00 73.30  ? 251 ILE C CA    1 
ATOM   4677 C C     . ILE B 2 248 ? 266.097 161.303 224.509 1.00 73.30  ? 251 ILE C C     1 
ATOM   4678 O O     . ILE B 2 248 ? 266.763 162.149 223.902 1.00 73.30  ? 251 ILE C O     1 
ATOM   4679 C CB    . ILE B 2 248 ? 266.034 159.352 222.874 1.00 73.30  ? 251 ILE C CB    1 
ATOM   4680 C CG1   . ILE B 2 248 ? 266.784 160.109 221.794 1.00 73.30  ? 251 ILE C CG1   1 
ATOM   4681 C CG2   . ILE B 2 248 ? 265.127 158.337 222.186 1.00 73.30  ? 251 ILE C CG2   1 
ATOM   4682 C CD1   . ILE B 2 248 ? 267.715 159.243 221.021 1.00 73.30  ? 251 ILE C CD1   1 
ATOM   4683 N N     . HIS B 2 249 ? 266.069 161.227 225.833 1.00 77.72  ? 252 HIS C N     1 
ATOM   4684 C CA    . HIS B 2 249 ? 266.738 162.213 226.664 1.00 77.72  ? 252 HIS C CA    1 
ATOM   4685 C C     . HIS B 2 249 ? 268.158 161.779 226.992 1.00 77.72  ? 252 HIS C C     1 
ATOM   4686 O O     . HIS B 2 249 ? 268.481 160.587 227.013 1.00 77.72  ? 252 HIS C O     1 
ATOM   4687 C CB    . HIS B 2 249 ? 265.964 162.432 227.958 1.00 77.72  ? 252 HIS C CB    1 
ATOM   4688 C CG    . HIS B 2 249 ? 264.503 162.680 227.759 1.00 77.72  ? 252 HIS C CG    1 
ATOM   4689 N ND1   . HIS B 2 249 ? 263.940 163.927 227.905 1.00 77.72  ? 252 HIS C ND1   1 
ATOM   4690 C CD2   . HIS B 2 249 ? 263.484 161.839 227.463 1.00 77.72  ? 252 HIS C CD2   1 
ATOM   4691 C CE1   . HIS B 2 249 ? 262.639 163.848 227.693 1.00 77.72  ? 252 HIS C CE1   1 
ATOM   4692 N NE2   . HIS B 2 249 ? 262.336 162.592 227.423 1.00 77.72  ? 252 HIS C NE2   1 
ATOM   4693 N N     . PHE B 2 250 ? 269.008 162.764 227.251 1.00 80.04  ? 253 PHE C N     1 
ATOM   4694 C CA    . PHE B 2 250 ? 270.410 162.518 227.535 1.00 80.04  ? 253 PHE C CA    1 
ATOM   4695 C C     . PHE B 2 250 ? 270.770 163.128 228.879 1.00 80.04  ? 253 PHE C C     1 
ATOM   4696 O O     . PHE B 2 250 ? 270.213 164.152 229.288 1.00 80.04  ? 253 PHE C O     1 
ATOM   4697 C CB    . PHE B 2 250 ? 271.303 163.081 226.428 1.00 80.04  ? 253 PHE C CB    1 
ATOM   4698 C CG    . PHE B 2 250 ? 271.281 162.262 225.173 1.00 80.04  ? 253 PHE C CG    1 
ATOM   4699 C CD1   . PHE B 2 250 ? 271.933 161.045 225.112 1.00 80.04  ? 253 PHE C CD1   1 
ATOM   4700 C CD2   . PHE B 2 250 ? 270.588 162.698 224.064 1.00 80.04  ? 253 PHE C CD2   1 
ATOM   4701 C CE1   . PHE B 2 250 ? 271.901 160.288 223.966 1.00 80.04  ? 253 PHE C CE1   1 
ATOM   4702 C CE2   . PHE B 2 250 ? 270.556 161.944 222.919 1.00 80.04  ? 253 PHE C CE2   1 
ATOM   4703 C CZ    . PHE B 2 250 ? 271.212 160.740 222.870 1.00 80.04  ? 253 PHE C CZ    1 
ATOM   4704 N N     . GLY B 2 251 ? 271.695 162.468 229.566 1.00 86.45  ? 254 GLY C N     1 
ATOM   4705 C CA    . GLY B 2 251 ? 272.132 162.892 230.878 1.00 86.45  ? 254 GLY C CA    1 
ATOM   4706 C C     . GLY B 2 251 ? 272.794 164.257 230.863 1.00 86.45  ? 254 GLY C C     1 
ATOM   4707 O O     . GLY B 2 251 ? 272.890 164.947 229.846 1.00 86.45  ? 254 GLY C O     1 
ATOM   4708 N N     . ALA B 2 252 ? 273.260 164.651 232.048 1.00 88.54  ? 255 ALA C N     1 
ATOM   4709 C CA    . ALA B 2 252 ? 273.864 165.970 232.206 1.00 88.54  ? 255 ALA C CA    1 
ATOM   4710 C C     . ALA B 2 252 ? 275.071 166.143 231.295 1.00 88.54  ? 255 ALA C C     1 
ATOM   4711 O O     . ALA B 2 252 ? 275.225 167.185 230.648 1.00 88.54  ? 255 ALA C O     1 
ATOM   4712 C CB    . ALA B 2 252 ? 274.258 166.197 233.666 1.00 88.54  ? 255 ALA C CB    1 
ATOM   4713 N N     . THR B 2 253 ? 275.930 165.130 231.217 1.00 87.53  ? 256 THR C N     1 
ATOM   4714 C CA    . THR B 2 253 ? 277.147 165.209 230.424 1.00 87.53  ? 256 THR C CA    1 
ATOM   4715 C C     . THR B 2 253 ? 277.054 164.460 229.102 1.00 87.53  ? 256 THR C C     1 
ATOM   4716 O O     . THR B 2 253 ? 277.995 164.525 228.304 1.00 87.53  ? 256 THR C O     1 
ATOM   4717 C CB    . THR B 2 253 ? 278.336 164.671 231.230 1.00 87.53  ? 256 THR C CB    1 
ATOM   4718 O OG1   . THR B 2 253 ? 279.563 165.071 230.606 1.00 87.53  ? 256 THR C OG1   1 
ATOM   4719 C CG2   . THR B 2 253 ? 278.278 163.155 231.304 1.00 87.53  ? 256 THR C CG2   1 
ATOM   4720 N N     . GLY B 2 254 ? 275.955 163.756 228.846 1.00 84.34  ? 257 GLY C N     1 
ATOM   4721 C CA    . GLY B 2 254 ? 275.785 163.101 227.567 1.00 84.34  ? 257 GLY C CA    1 
ATOM   4722 C C     . GLY B 2 254 ? 275.567 161.604 227.628 1.00 84.34  ? 257 GLY C C     1 
ATOM   4723 O O     . GLY B 2 254 ? 275.845 160.901 226.654 1.00 84.34  ? 257 GLY C O     1 
ATOM   4724 N N     . LYS B 2 255 ? 275.073 161.097 228.752 1.00 84.69  ? 258 LYS C N     1 
ATOM   4725 C CA    . LYS B 2 255 ? 274.724 159.688 228.858 1.00 84.69  ? 258 LYS C CA    1 
ATOM   4726 C C     . LYS B 2 255 ? 273.242 159.485 228.577 1.00 84.69  ? 258 LYS C C     1 
ATOM   4727 O O     . LYS B 2 255 ? 272.398 160.271 229.012 1.00 84.69  ? 258 LYS C O     1 
ATOM   4728 C CB    . LYS B 2 255 ? 275.073 159.132 230.238 1.00 84.69  ? 258 LYS C CB    1 
ATOM   4729 C CG    . LYS B 2 255 ? 276.560 159.054 230.517 1.00 84.69  ? 258 LYS C CG    1 
ATOM   4730 C CD    . LYS B 2 255 ? 277.255 158.145 229.508 1.00 84.69  ? 258 LYS C CD    1 
ATOM   4731 C CE    . LYS B 2 255 ? 276.777 156.704 229.624 1.00 84.69  ? 258 LYS C CE    1 
ATOM   4732 N NZ    . LYS B 2 255 ? 277.124 156.094 230.937 1.00 84.69  ? 258 LYS C NZ    1 
ATOM   4733 N N     . LEU B 2 256 ? 272.939 158.414 227.848 1.00 82.79  ? 259 LEU C N     1 
ATOM   4734 C CA    . LEU B 2 256 ? 271.572 158.142 227.428 1.00 82.79  ? 259 LEU C CA    1 
ATOM   4735 C C     . LEU B 2 256 ? 270.672 157.899 228.632 1.00 82.79  ? 259 LEU C C     1 
ATOM   4736 O O     . LEU B 2 256 ? 271.032 157.170 229.559 1.00 82.79  ? 259 LEU C O     1 
ATOM   4737 C CB    . LEU B 2 256 ? 271.551 156.932 226.496 1.00 82.79  ? 259 LEU C CB    1 
ATOM   4738 C CG    . LEU B 2 256 ? 270.217 156.523 225.874 1.00 82.79  ? 259 LEU C CG    1 
ATOM   4739 C CD1   . LEU B 2 256 ? 269.800 157.518 224.816 1.00 82.79  ? 259 LEU C CD1   1 
ATOM   4740 C CD2   . LEU B 2 256 ? 270.320 155.130 225.284 1.00 82.79  ? 259 LEU C CD2   1 
ATOM   4741 N N     . ALA B 2 257 ? 269.498 158.515 228.610 1.00 82.81  ? 260 ALA C N     1 
ATOM   4742 C CA    . ALA B 2 257 ? 268.476 158.352 229.632 1.00 82.81  ? 260 ALA C CA    1 
ATOM   4743 C C     . ALA B 2 257 ? 267.234 157.745 228.981 1.00 82.81  ? 260 ALA C C     1 
ATOM   4744 O O     . ALA B 2 257 ? 267.261 157.323 227.823 1.00 82.81  ? 260 ALA C O     1 
ATOM   4745 C CB    . ALA B 2 257 ? 268.173 159.686 230.316 1.00 82.81  ? 260 ALA C CB    1 
ATOM   4746 N N     . SER B 2 258 ? 266.143 157.691 229.740 1.00 83.35  ? 261 SER C N     1 
ATOM   4747 C CA    . SER B 2 258 ? 264.919 157.089 229.238 1.00 83.35  ? 261 SER C CA    1 
ATOM   4748 C C     . SER B 2 258 ? 264.381 157.875 228.042 1.00 83.35  ? 261 SER C C     1 
ATOM   4749 O O     . SER B 2 258 ? 264.852 158.963 227.708 1.00 83.35  ? 261 SER C O     1 
ATOM   4750 C CB    . SER B 2 258 ? 263.865 157.024 230.339 1.00 83.35  ? 261 SER C CB    1 
ATOM   4751 O OG    . SER B 2 258 ? 262.608 156.638 229.814 1.00 83.35  ? 261 SER C OG    1 
ATOM   4752 N N     . ALA B 2 259 ? 263.370 157.302 227.394 1.00 77.65  ? 262 ALA C N     1 
ATOM   4753 C CA    . ALA B 2 259 ? 262.765 157.903 226.213 1.00 77.65  ? 262 ALA C CA    1 
ATOM   4754 C C     . ALA B 2 259 ? 261.253 157.843 226.337 1.00 77.65  ? 262 ALA C C     1 
ATOM   4755 O O     . ALA B 2 259 ? 260.691 156.769 226.566 1.00 77.65  ? 262 ALA C O     1 
ATOM   4756 C CB    . ALA B 2 259 ? 263.217 157.191 224.938 1.00 77.65  ? 262 ALA C CB    1 
ATOM   4757 N N     . ASP B 2 260 ? 260.601 158.989 226.180 1.00 71.93  ? 263 ASP C N     1 
ATOM   4758 C CA    . ASP B 2 260 ? 259.151 159.066 226.137 1.00 71.93  ? 263 ASP C CA    1 
ATOM   4759 C C     . ASP B 2 260 ? 258.694 159.501 224.752 1.00 71.93  ? 263 ASP C C     1 
ATOM   4760 O O     . ASP B 2 260 ? 259.381 160.255 224.059 1.00 71.93  ? 263 ASP C O     1 
ATOM   4761 C CB    . ASP B 2 260 ? 258.610 160.032 227.197 1.00 71.93  ? 263 ASP C CB    1 
ATOM   4762 C CG    . ASP B 2 260 ? 259.156 161.441 227.051 1.00 71.93  ? 263 ASP C CG    1 
ATOM   4763 O OD1   . ASP B 2 260 ? 260.045 161.666 226.208 1.00 71.93  ? 263 ASP C OD1   1 
ATOM   4764 O OD2   . ASP B 2 260 ? 258.688 162.334 227.785 1.00 71.93  ? 263 ASP C OD2   1 
ATOM   4765 N N     . ILE B 2 261 ? 257.532 159.005 224.346 1.00 67.06  ? 264 ILE C N     1 
ATOM   4766 C CA    . ILE B 2 261 ? 256.932 159.359 223.068 1.00 67.06  ? 264 ILE C CA    1 
ATOM   4767 C C     . ILE B 2 261 ? 255.784 160.318 223.331 1.00 67.06  ? 264 ILE C C     1 
ATOM   4768 O O     . ILE B 2 261 ? 255.074 160.196 224.335 1.00 67.06  ? 264 ILE C O     1 
ATOM   4769 C CB    . ILE B 2 261 ? 256.456 158.116 222.292 1.00 67.06  ? 264 ILE C CB    1 
ATOM   4770 C CG1   . ILE B 2 261 ? 255.372 157.383 223.068 1.00 67.06  ? 264 ILE C CG1   1 
ATOM   4771 C CG2   . ILE B 2 261 ? 257.610 157.169 222.041 1.00 67.06  ? 264 ILE C CG2   1 
ATOM   4772 C CD1   . ILE B 2 261 ? 254.747 156.271 222.296 1.00 67.06  ? 264 ILE C CD1   1 
ATOM   4773 N N     . GLU B 2 262 ? 255.616 161.285 222.439 1.00 66.06  ? 265 GLU C N     1 
ATOM   4774 C CA    . GLU B 2 262 ? 254.567 162.285 222.566 1.00 66.06  ? 265 GLU C CA    1 
ATOM   4775 C C     . GLU B 2 262 ? 253.817 162.357 221.249 1.00 66.06  ? 265 GLU C C     1 
ATOM   4776 O O     . GLU B 2 262 ? 254.402 162.695 220.217 1.00 66.06  ? 265 GLU C O     1 
ATOM   4777 C CB    . GLU B 2 262 ? 255.145 163.651 222.937 1.00 66.06  ? 265 GLU C CB    1 
ATOM   4778 C CG    . GLU B 2 262 ? 254.116 164.760 222.942 1.00 66.06  ? 265 GLU C CG    1 
ATOM   4779 C CD    . GLU B 2 262 ? 254.617 166.015 223.625 1.00 66.06  ? 265 GLU C CD    1 
ATOM   4780 O OE1   . GLU B 2 262 ? 255.850 166.166 223.761 1.00 66.06  ? 265 GLU C OE1   1 
ATOM   4781 O OE2   . GLU B 2 262 ? 253.778 166.847 224.031 1.00 66.06  ? 265 GLU C OE2   1 
ATOM   4782 N N     . THR B 2 263 ? 252.531 162.040 221.288 1.00 64.88  ? 266 THR C N     1 
ATOM   4783 C CA    . THR B 2 263 ? 251.709 162.008 220.092 1.00 64.88  ? 266 THR C CA    1 
ATOM   4784 C C     . THR B 2 263 ? 251.042 163.360 219.895 1.00 64.88  ? 266 THR C C     1 
ATOM   4785 O O     . THR B 2 263 ? 250.654 164.023 220.860 1.00 64.88  ? 266 THR C O     1 
ATOM   4786 C CB    . THR B 2 263 ? 250.660 160.899 220.199 1.00 64.88  ? 266 THR C CB    1 
ATOM   4787 O OG1   . THR B 2 263 ? 251.289 159.629 219.996 1.00 64.88  ? 266 THR C OG1   1 
ATOM   4788 C CG2   . THR B 2 263 ? 249.567 161.076 219.168 1.00 64.88  ? 266 THR C CG2   1 
ATOM   4789 N N     . TYR B 2 264 ? 250.913 163.762 218.641 1.00 64.33  ? 267 TYR C N     1 
ATOM   4790 C CA    . TYR B 2 264 ? 250.336 165.040 218.270 1.00 64.33  ? 267 TYR C CA    1 
ATOM   4791 C C     . TYR B 2 264 ? 249.152 164.788 217.346 1.00 64.33  ? 267 TYR C C     1 
ATOM   4792 O O     . TYR B 2 264 ? 248.658 163.663 217.241 1.00 64.33  ? 267 TYR C O     1 
ATOM   4793 C CB    . TYR B 2 264 ? 251.394 165.950 217.651 1.00 64.33  ? 267 TYR C CB    1 
ATOM   4794 C CG    . TYR B 2 264 ? 252.264 166.605 218.691 1.00 64.33  ? 267 TYR C CG    1 
ATOM   4795 C CD1   . TYR B 2 264 ? 253.548 166.148 218.938 1.00 64.33  ? 267 TYR C CD1   1 
ATOM   4796 C CD2   . TYR B 2 264 ? 251.790 167.666 219.443 1.00 64.33  ? 267 TYR C CD2   1 
ATOM   4797 C CE1   . TYR B 2 264 ? 254.341 166.741 219.892 1.00 64.33  ? 267 TYR C CE1   1 
ATOM   4798 C CE2   . TYR B 2 264 ? 252.574 168.265 220.400 1.00 64.33  ? 267 TYR C CE2   1 
ATOM   4799 C CZ    . TYR B 2 264 ? 253.849 167.798 220.620 1.00 64.33  ? 267 TYR C CZ    1 
ATOM   4800 O OH    . TYR B 2 264 ? 254.636 168.394 221.576 1.00 64.33  ? 267 TYR C OH    1 
ATOM   4801 N N     . LEU B 2 265 ? 248.704 165.849 216.682 1.00 64.54  ? 268 LEU C N     1 
ATOM   4802 C CA    . LEU B 2 265 ? 247.363 165.950 216.120 1.00 64.54  ? 268 LEU C CA    1 
ATOM   4803 C C     . LEU B 2 265 ? 246.910 164.674 215.425 1.00 64.54  ? 268 LEU C C     1 
ATOM   4804 O O     . LEU B 2 265 ? 247.536 164.208 214.471 1.00 64.54  ? 268 LEU C O     1 
ATOM   4805 C CB    . LEU B 2 265 ? 247.326 167.144 215.157 1.00 64.54  ? 268 LEU C CB    1 
ATOM   4806 C CG    . LEU B 2 265 ? 248.393 167.264 214.065 1.00 64.54  ? 268 LEU C CG    1 
ATOM   4807 C CD1   . LEU B 2 265 ? 247.957 166.671 212.734 1.00 64.54  ? 268 LEU C CD1   1 
ATOM   4808 C CD2   . LEU B 2 265 ? 248.819 168.708 213.908 1.00 64.54  ? 268 LEU C CD2   1 
ATOM   4809 N N     . LEU B 2 266 ? 245.829 164.098 215.942 1.00 64.24  ? 269 LEU C N     1 
ATOM   4810 C CA    . LEU B 2 266 ? 245.277 162.838 215.475 1.00 64.24  ? 269 LEU C CA    1 
ATOM   4811 C C     . LEU B 2 266 ? 244.044 163.108 214.629 1.00 64.24  ? 269 LEU C C     1 
ATOM   4812 O O     . LEU B 2 266 ? 243.183 163.907 215.008 1.00 64.24  ? 269 LEU C O     1 
ATOM   4813 C CB    . LEU B 2 266 ? 244.910 161.932 216.654 1.00 64.24  ? 269 LEU C CB    1 
ATOM   4814 C CG    . LEU B 2 266 ? 244.264 160.573 216.361 1.00 64.24  ? 269 LEU C CG    1 
ATOM   4815 C CD1   . LEU B 2 266 ? 245.210 159.653 215.624 1.00 64.24  ? 269 LEU C CD1   1 
ATOM   4816 C CD2   . LEU B 2 266 ? 243.778 159.924 217.643 1.00 64.24  ? 269 LEU C CD2   1 
ATOM   4817 N N     . GLU B 2 267 ? 243.964 162.441 213.482 1.00 68.44  ? 270 GLU C N     1 
ATOM   4818 C CA    . GLU B 2 267 ? 242.818 162.583 212.589 1.00 68.44  ? 270 GLU C CA    1 
ATOM   4819 C C     . GLU B 2 267 ? 241.667 161.786 213.194 1.00 68.44  ? 270 GLU C C     1 
ATOM   4820 O O     . GLU B 2 267 ? 241.379 160.647 212.818 1.00 68.44  ? 270 GLU C O     1 
ATOM   4821 C CB    . GLU B 2 267 ? 243.181 162.118 211.186 1.00 68.44  ? 270 GLU C CB    1 
ATOM   4822 C CG    . GLU B 2 267 ? 242.045 162.123 210.194 1.00 68.44  ? 270 GLU C CG    1 
ATOM   4823 C CD    . GLU B 2 267 ? 242.346 161.271 208.981 1.00 68.44  ? 270 GLU C CD    1 
ATOM   4824 O OE1   . GLU B 2 267 ? 242.218 160.033 209.075 1.00 68.44  ? 270 GLU C OE1   1 
ATOM   4825 O OE2   . GLU B 2 267 ? 242.717 161.838 207.935 1.00 68.44  ? 270 GLU C OE2   1 
ATOM   4826 N N     . LYS B 2 268 ? 241.005 162.406 214.171 1.00 64.78  ? 271 LYS C N     1 
ATOM   4827 C CA    . LYS B 2 268 ? 239.963 161.734 214.935 1.00 64.78  ? 271 LYS C CA    1 
ATOM   4828 C C     . LYS B 2 268 ? 238.622 161.726 214.221 1.00 64.78  ? 271 LYS C C     1 
ATOM   4829 O O     . LYS B 2 268 ? 237.749 160.934 214.585 1.00 64.78  ? 271 LYS C O     1 
ATOM   4830 C CB    . LYS B 2 268 ? 239.827 162.388 216.311 1.00 64.78  ? 271 LYS C CB    1 
ATOM   4831 C CG    . LYS B 2 268 ? 239.363 163.830 216.267 1.00 64.78  ? 271 LYS C CG    1 
ATOM   4832 C CD    . LYS B 2 268 ? 239.460 164.486 217.635 1.00 64.78  ? 271 LYS C CD    1 
ATOM   4833 C CE    . LYS B 2 268 ? 238.403 163.964 218.587 1.00 64.78  ? 271 LYS C CE    1 
ATOM   4834 N NZ    . LYS B 2 268 ? 238.453 164.664 219.898 1.00 64.78  ? 271 LYS C NZ    1 
ATOM   4835 N N     . SER B 2 269 ? 238.438 162.576 213.213 1.00 65.12  ? 272 SER C N     1 
ATOM   4836 C CA    . SER B 2 269 ? 237.230 162.527 212.400 1.00 65.12  ? 272 SER C CA    1 
ATOM   4837 C C     . SER B 2 269 ? 237.152 161.280 211.535 1.00 65.12  ? 272 SER C C     1 
ATOM   4838 O O     . SER B 2 269 ? 236.177 161.121 210.797 1.00 65.12  ? 272 SER C O     1 
ATOM   4839 C CB    . SER B 2 269 ? 237.142 163.772 211.520 1.00 65.12  ? 272 SER C CB    1 
ATOM   4840 O OG    . SER B 2 269 ? 238.194 163.797 210.575 1.00 65.12  ? 272 SER C OG    1 
ATOM   4841 N N     . ARG B 2 270 ? 238.153 160.403 211.602 1.00 68.14  ? 273 ARG C N     1 
ATOM   4842 C CA    . ARG B 2 270 ? 238.120 159.162 210.839 1.00 68.14  ? 273 ARG C CA    1 
ATOM   4843 C C     . ARG B 2 270 ? 237.310 158.091 211.555 1.00 68.14  ? 273 ARG C C     1 
ATOM   4844 O O     . ARG B 2 270 ? 236.802 157.165 210.913 1.00 68.14  ? 273 ARG C O     1 
ATOM   4845 C CB    . ARG B 2 270 ? 239.550 158.685 210.585 1.00 68.14  ? 273 ARG C CB    1 
ATOM   4846 C CG    . ARG B 2 270 ? 239.688 157.241 210.156 1.00 68.14  ? 273 ARG C CG    1 
ATOM   4847 C CD    . ARG B 2 270 ? 241.035 156.994 209.521 1.00 68.14  ? 273 ARG C CD    1 
ATOM   4848 N NE    . ARG B 2 270 ? 241.337 157.969 208.484 1.00 68.14  ? 273 ARG C NE    1 
ATOM   4849 C CZ    . ARG B 2 270 ? 241.541 157.657 207.211 1.00 68.14  ? 273 ARG C CZ    1 
ATOM   4850 N NH1   . ARG B 2 270 ? 241.477 156.393 206.820 1.00 68.14  ? 273 ARG C NH1   1 
ATOM   4851 N NH2   . ARG B 2 270 ? 241.809 158.608 206.329 1.00 68.14  ? 273 ARG C NH2   1 
ATOM   4852 N N     . VAL B 2 271 ? 237.159 158.213 212.875 1.00 65.82  ? 274 VAL C N     1 
ATOM   4853 C CA    . VAL B 2 271 ? 236.405 157.226 213.642 1.00 65.82  ? 274 VAL C CA    1 
ATOM   4854 C C     . VAL B 2 271 ? 234.961 157.157 213.169 1.00 65.82  ? 274 VAL C C     1 
ATOM   4855 O O     . VAL B 2 271 ? 234.308 156.114 213.289 1.00 65.82  ? 274 VAL C O     1 
ATOM   4856 C CB    . VAL B 2 271 ? 236.487 157.555 215.145 1.00 65.82  ? 274 VAL C CB    1 
ATOM   4857 C CG1   . VAL B 2 271 ? 235.907 156.427 215.970 1.00 65.82  ? 274 VAL C CG1   1 
ATOM   4858 C CG2   . VAL B 2 271 ? 237.918 157.836 215.548 1.00 65.82  ? 274 VAL C CG2   1 
ATOM   4859 N N     . ILE B 2 272 ? 234.442 158.252 212.618 1.00 69.51  ? 275 ILE C N     1 
ATOM   4860 C CA    . ILE B 2 272 ? 233.042 158.344 212.220 1.00 69.51  ? 275 ILE C CA    1 
ATOM   4861 C C     . ILE B 2 272 ? 232.882 158.039 210.741 1.00 69.51  ? 275 ILE C C     1 
ATOM   4862 O O     . ILE B 2 272 ? 232.134 157.136 210.355 1.00 69.51  ? 275 ILE C O     1 
ATOM   4863 C CB    . ILE B 2 272 ? 232.476 159.740 212.516 1.00 69.51  ? 275 ILE C CB    1 
ATOM   4864 C CG1   . ILE B 2 272 ? 232.403 159.999 214.012 1.00 69.51  ? 275 ILE C CG1   1 
ATOM   4865 C CG2   . ILE B 2 272 ? 231.108 159.893 211.890 1.00 69.51  ? 275 ILE C CG2   1 
ATOM   4866 C CD1   . ILE B 2 272 ? 232.020 161.415 214.315 1.00 69.51  ? 275 ILE C CD1   1 
ATOM   4867 N N     . PHE B 2 273 ? 233.578 158.800 209.904 1.00 74.36  ? 276 PHE C N     1 
ATOM   4868 C CA    . PHE B 2 273 ? 233.310 158.859 208.476 1.00 74.36  ? 276 PHE C CA    1 
ATOM   4869 C C     . PHE B 2 273 ? 234.554 158.469 207.696 1.00 74.36  ? 276 PHE C C     1 
ATOM   4870 O O     . PHE B 2 273 ? 235.639 159.004 207.942 1.00 74.36  ? 276 PHE C O     1 
ATOM   4871 C CB    . PHE B 2 273 ? 232.850 160.262 208.079 1.00 74.36  ? 276 PHE C CB    1 
ATOM   4872 C CG    . PHE B 2 273 ? 232.855 160.505 206.604 1.00 74.36  ? 276 PHE C CG    1 
ATOM   4873 C CD1   . PHE B 2 273 ? 231.840 160.013 205.804 1.00 74.36  ? 276 PHE C CD1   1 
ATOM   4874 C CD2   . PHE B 2 273 ? 233.871 161.237 206.016 1.00 74.36  ? 276 PHE C CD2   1 
ATOM   4875 C CE1   . PHE B 2 273 ? 231.843 160.239 204.446 1.00 74.36  ? 276 PHE C CE1   1 
ATOM   4876 C CE2   . PHE B 2 273 ? 233.878 161.467 204.659 1.00 74.36  ? 276 PHE C CE2   1 
ATOM   4877 C CZ    . PHE B 2 273 ? 232.864 160.968 203.873 1.00 74.36  ? 276 PHE C CZ    1 
ATOM   4878 N N     . GLN B 2 274 ? 234.392 157.546 206.755 1.00 76.20  ? 277 GLN C N     1 
ATOM   4879 C CA    . GLN B 2 274 ? 235.473 157.093 205.895 1.00 76.20  ? 277 GLN C CA    1 
ATOM   4880 C C     . GLN B 2 274 ? 235.089 157.322 204.442 1.00 76.20  ? 277 GLN C C     1 
ATOM   4881 O O     . GLN B 2 274 ? 233.969 157.008 204.031 1.00 76.20  ? 277 GLN C O     1 
ATOM   4882 C CB    . GLN B 2 274 ? 235.775 155.613 206.117 1.00 76.20  ? 277 GLN C CB    1 
ATOM   4883 C CG    . GLN B 2 274 ? 236.204 155.285 207.523 1.00 76.20  ? 277 GLN C CG    1 
ATOM   4884 C CD    . GLN B 2 274 ? 235.022 155.081 208.438 1.00 76.20  ? 277 GLN C CD    1 
ATOM   4885 O OE1   . GLN B 2 274 ? 233.913 154.821 207.982 1.00 76.20  ? 277 GLN C OE1   1 
ATOM   4886 N NE2   . GLN B 2 274 ? 235.248 155.219 209.736 1.00 76.20  ? 277 GLN C NE2   1 
ATOM   4887 N N     . LEU B 2 275 ? 236.021 157.862 203.663 1.00 82.71  ? 278 LEU C N     1 
ATOM   4888 C CA    . LEU B 2 275 ? 235.797 158.007 202.235 1.00 82.71  ? 278 LEU C CA    1 
ATOM   4889 C C     . LEU B 2 275 ? 235.726 156.629 201.580 1.00 82.71  ? 278 LEU C C     1 
ATOM   4890 O O     . LEU B 2 275 ? 235.917 155.591 202.219 1.00 82.71  ? 278 LEU C O     1 
ATOM   4891 C CB    . LEU B 2 275 ? 236.899 158.852 201.598 1.00 82.71  ? 278 LEU C CB    1 
ATOM   4892 C CG    . LEU B 2 275 ? 236.861 160.372 201.778 1.00 82.71  ? 278 LEU C CG    1 
ATOM   4893 C CD1   . LEU B 2 275 ? 237.287 160.789 203.176 1.00 82.71  ? 278 LEU C CD1   1 
ATOM   4894 C CD2   . LEU B 2 275 ? 237.731 161.047 200.736 1.00 82.71  ? 278 LEU C CD2   1 
ATOM   4895 N N     . LYS B 2 276 ? 235.441 156.618 200.284 1.00 86.56  ? 279 LYS C N     1 
ATOM   4896 C CA    . LYS B 2 276 ? 235.431 155.362 199.554 1.00 86.56  ? 279 LYS C CA    1 
ATOM   4897 C C     . LYS B 2 276 ? 236.857 154.862 199.353 1.00 86.56  ? 279 LYS C C     1 
ATOM   4898 O O     . LYS B 2 276 ? 237.798 155.645 199.207 1.00 86.56  ? 279 LYS C O     1 
ATOM   4899 C CB    . LYS B 2 276 ? 234.729 155.529 198.208 1.00 86.56  ? 279 LYS C CB    1 
ATOM   4900 C CG    . LYS B 2 276 ? 234.395 154.214 197.524 1.00 86.56  ? 279 LYS C CG    1 
ATOM   4901 C CD    . LYS B 2 276 ? 233.467 153.372 198.381 1.00 86.56  ? 279 LYS C CD    1 
ATOM   4902 C CE    . LYS B 2 276 ? 232.083 153.992 198.472 1.00 86.56  ? 279 LYS C CE    1 
ATOM   4903 N NZ    . LYS B 2 276 ? 231.061 152.996 198.897 1.00 86.56  ? 279 LYS C NZ    1 
ATOM   4904 N N     . ALA B 2 277 ? 237.007 153.537 199.370 1.00 86.17  ? 280 ALA C N     1 
ATOM   4905 C CA    . ALA B 2 277 ? 238.311 152.882 199.268 1.00 86.17  ? 280 ALA C CA    1 
ATOM   4906 C C     . ALA B 2 277 ? 239.218 153.280 200.430 1.00 86.17  ? 280 ALA C C     1 
ATOM   4907 O O     . ALA B 2 277 ? 240.402 153.570 200.250 1.00 86.17  ? 280 ALA C O     1 
ATOM   4908 C CB    . ALA B 2 277 ? 238.983 153.172 197.924 1.00 86.17  ? 280 ALA C CB    1 
ATOM   4909 N N     . GLU B 2 278 ? 238.652 153.293 201.635 1.00 82.37  ? 281 GLU C N     1 
ATOM   4910 C CA    . GLU B 2 278 ? 239.405 153.554 202.850 1.00 82.37  ? 281 GLU C CA    1 
ATOM   4911 C C     . GLU B 2 278 ? 238.771 152.782 203.995 1.00 82.37  ? 281 GLU C C     1 
ATOM   4912 O O     . GLU B 2 278 ? 237.676 152.231 203.872 1.00 82.37  ? 281 GLU C O     1 
ATOM   4913 C CB    . GLU B 2 278 ? 239.455 155.047 203.185 1.00 82.37  ? 281 GLU C CB    1 
ATOM   4914 C CG    . GLU B 2 278 ? 240.573 155.807 202.507 1.00 82.37  ? 281 GLU C CG    1 
ATOM   4915 C CD    . GLU B 2 278 ? 240.684 157.233 203.005 1.00 82.37  ? 281 GLU C CD    1 
ATOM   4916 O OE1   . GLU B 2 278 ? 239.921 157.601 203.921 1.00 82.37  ? 281 GLU C OE1   1 
ATOM   4917 O OE2   . GLU B 2 278 ? 241.532 157.986 202.484 1.00 82.37  ? 281 GLU C OE2   1 
ATOM   4918 N N     . ARG B 2 279 ? 239.483 152.743 205.114 1.00 76.67  ? 282 ARG C N     1 
ATOM   4919 C CA    . ARG B 2 279 ? 238.987 152.174 206.354 1.00 76.67  ? 282 ARG C CA    1 
ATOM   4920 C C     . ARG B 2 279 ? 239.322 153.129 207.490 1.00 76.67  ? 282 ARG C C     1 
ATOM   4921 O O     . ARG B 2 279 ? 240.061 154.101 207.313 1.00 76.67  ? 282 ARG C O     1 
ATOM   4922 C CB    . ARG B 2 279 ? 239.595 150.793 206.629 1.00 76.67  ? 282 ARG C CB    1 
ATOM   4923 C CG    . ARG B 2 279 ? 239.404 149.778 205.524 1.00 76.67  ? 282 ARG C CG    1 
ATOM   4924 C CD    . ARG B 2 279 ? 239.502 148.367 206.069 1.00 76.67  ? 282 ARG C CD    1 
ATOM   4925 N NE    . ARG B 2 279 ? 240.786 148.125 206.718 1.00 76.67  ? 282 ARG C NE    1 
ATOM   4926 C CZ    . ARG B 2 279 ? 241.107 146.995 207.339 1.00 76.67  ? 282 ARG C CZ    1 
ATOM   4927 N NH1   . ARG B 2 279 ? 240.237 145.999 207.400 1.00 76.67  ? 282 ARG C NH1   1 
ATOM   4928 N NH2   . ARG B 2 279 ? 242.298 146.862 207.903 1.00 76.67  ? 282 ARG C NH2   1 
ATOM   4929 N N     . ASN B 2 280 ? 238.773 152.854 208.664 1.00 70.87  ? 283 ASN C N     1 
ATOM   4930 C CA    . ASN B 2 280 ? 239.200 153.549 209.863 1.00 70.87  ? 283 ASN C CA    1 
ATOM   4931 C C     . ASN B 2 280 ? 240.266 152.705 210.553 1.00 70.87  ? 283 ASN C C     1 
ATOM   4932 O O     . ASN B 2 280 ? 240.800 151.753 209.980 1.00 70.87  ? 283 ASN C O     1 
ATOM   4933 C CB    . ASN B 2 280 ? 238.010 153.868 210.773 1.00 70.87  ? 283 ASN C CB    1 
ATOM   4934 C CG    . ASN B 2 280 ? 237.283 152.636 211.244 1.00 70.87  ? 283 ASN C CG    1 
ATOM   4935 O OD1   . ASN B 2 280 ? 237.500 151.543 210.734 1.00 70.87  ? 283 ASN C OD1   1 
ATOM   4936 N ND2   . ASN B 2 280 ? 236.404 152.808 212.223 1.00 70.87  ? 283 ASN C ND2   1 
ATOM   4937 N N     . TYR B 2 281 ? 240.592 153.064 211.790 1.00 67.85  ? 284 TYR C N     1 
ATOM   4938 C CA    . TYR B 2 281 ? 241.732 152.473 212.474 1.00 67.85  ? 284 TYR C CA    1 
ATOM   4939 C C     . TYR B 2 281 ? 241.579 150.963 212.604 1.00 67.85  ? 284 TYR C C     1 
ATOM   4940 O O     . TYR B 2 281 ? 240.474 150.432 212.728 1.00 67.85  ? 284 TYR C O     1 
ATOM   4941 C CB    . TYR B 2 281 ? 241.901 153.132 213.835 1.00 67.85  ? 284 TYR C CB    1 
ATOM   4942 C CG    . TYR B 2 281 ? 242.054 154.624 213.707 1.00 67.85  ? 284 TYR C CG    1 
ATOM   4943 C CD1   . TYR B 2 281 ? 243.237 155.178 213.252 1.00 67.85  ? 284 TYR C CD1   1 
ATOM   4944 C CD2   . TYR B 2 281 ? 241.008 155.477 214.009 1.00 67.85  ? 284 TYR C CD2   1 
ATOM   4945 C CE1   . TYR B 2 281 ? 243.383 156.537 213.122 1.00 67.85  ? 284 TYR C CE1   1 
ATOM   4946 C CE2   . TYR B 2 281 ? 241.145 156.839 213.881 1.00 67.85  ? 284 TYR C CE2   1 
ATOM   4947 C CZ    . TYR B 2 281 ? 242.334 157.363 213.436 1.00 67.85  ? 284 TYR C CZ    1 
ATOM   4948 O OH    . TYR B 2 281 ? 242.479 158.721 213.306 1.00 67.85  ? 284 TYR C OH    1 
ATOM   4949 N N     . HIS B 2 282 ? 242.718 150.271 212.568 1.00 70.43  ? 285 HIS C N     1 
ATOM   4950 C CA    . HIS B 2 282 ? 242.719 148.828 212.358 1.00 70.43  ? 285 HIS C CA    1 
ATOM   4951 C C     . HIS B 2 282 ? 242.067 148.064 213.499 1.00 70.43  ? 285 HIS C C     1 
ATOM   4952 O O     . HIS B 2 282 ? 241.562 146.960 213.280 1.00 70.43  ? 285 HIS C O     1 
ATOM   4953 C CB    . HIS B 2 282 ? 244.148 148.333 212.152 1.00 70.43  ? 285 HIS C CB    1 
ATOM   4954 C CG    . HIS B 2 282 ? 244.756 148.776 210.861 1.00 70.43  ? 285 HIS C CG    1 
ATOM   4955 N ND1   . HIS B 2 282 ? 246.102 149.034 210.723 1.00 70.43  ? 285 HIS C ND1   1 
ATOM   4956 C CD2   . HIS B 2 282 ? 244.201 149.010 209.649 1.00 70.43  ? 285 HIS C CD2   1 
ATOM   4957 C CE1   . HIS B 2 282 ? 246.349 149.405 209.480 1.00 70.43  ? 285 HIS C CE1   1 
ATOM   4958 N NE2   . HIS B 2 282 ? 245.213 149.399 208.808 1.00 70.43  ? 285 HIS C NE2   1 
ATOM   4959 N N     . ILE B 2 283 ? 242.072 148.622 214.714 1.00 70.41  ? 286 ILE C N     1 
ATOM   4960 C CA    . ILE B 2 283 ? 241.632 147.870 215.890 1.00 70.41  ? 286 ILE C CA    1 
ATOM   4961 C C     . ILE B 2 283 ? 240.226 147.320 215.700 1.00 70.41  ? 286 ILE C C     1 
ATOM   4962 O O     . ILE B 2 283 ? 239.906 146.222 216.170 1.00 70.41  ? 286 ILE C O     1 
ATOM   4963 C CB    . ILE B 2 283 ? 241.734 148.743 217.156 1.00 70.41  ? 286 ILE C CB    1 
ATOM   4964 C CG1   . ILE B 2 283 ? 241.402 147.919 218.402 1.00 70.41  ? 286 ILE C CG1   1 
ATOM   4965 C CG2   . ILE B 2 283 ? 240.844 149.969 217.053 1.00 70.41  ? 286 ILE C CG2   1 
ATOM   4966 C CD1   . ILE B 2 283 ? 242.385 146.818 218.694 1.00 70.41  ? 286 ILE C CD1   1 
ATOM   4967 N N     . PHE B 2 284 ? 239.374 148.053 214.982 1.00 68.60  ? 287 PHE C N     1 
ATOM   4968 C CA    . PHE B 2 284 ? 237.996 147.613 214.801 1.00 68.60  ? 287 PHE C CA    1 
ATOM   4969 C C     . PHE B 2 284 ? 237.939 146.304 214.029 1.00 68.60  ? 287 PHE C C     1 
ATOM   4970 O O     . PHE B 2 284 ? 237.379 145.311 214.507 1.00 68.60  ? 287 PHE C O     1 
ATOM   4971 C CB    . PHE B 2 284 ? 237.192 148.699 214.091 1.00 68.60  ? 287 PHE C CB    1 
ATOM   4972 C CG    . PHE B 2 284 ? 236.976 149.926 214.923 1.00 68.60  ? 287 PHE C CG    1 
ATOM   4973 C CD1   . PHE B 2 284 ? 237.840 150.999 214.837 1.00 68.60  ? 287 PHE C CD1   1 
ATOM   4974 C CD2   . PHE B 2 284 ? 235.915 150.003 215.800 1.00 68.60  ? 287 PHE C CD2   1 
ATOM   4975 C CE1   . PHE B 2 284 ? 237.643 152.125 215.603 1.00 68.60  ? 287 PHE C CE1   1 
ATOM   4976 C CE2   . PHE B 2 284 ? 235.716 151.126 216.566 1.00 68.60  ? 287 PHE C CE2   1 
ATOM   4977 C CZ    . PHE B 2 284 ? 236.581 152.187 216.468 1.00 68.60  ? 287 PHE C CZ    1 
ATOM   4978 N N     . TYR B 2 285 ? 238.539 146.274 212.840 1.00 73.37  ? 288 TYR C N     1 
ATOM   4979 C CA    . TYR B 2 285 ? 238.523 145.055 212.041 1.00 73.37  ? 288 TYR C CA    1 
ATOM   4980 C C     . TYR B 2 285 ? 239.366 143.956 212.672 1.00 73.37  ? 288 TYR C C     1 
ATOM   4981 O O     . TYR B 2 285 ? 239.073 142.772 212.479 1.00 73.37  ? 288 TYR C O     1 
ATOM   4982 C CB    . TYR B 2 285 ? 239.004 145.352 210.627 1.00 73.37  ? 288 TYR C CB    1 
ATOM   4983 C CG    . TYR B 2 285 ? 238.488 146.661 210.090 1.00 73.37  ? 288 TYR C CG    1 
ATOM   4984 C CD1   . TYR B 2 285 ? 237.199 146.769 209.600 1.00 73.37  ? 288 TYR C CD1   1 
ATOM   4985 C CD2   . TYR B 2 285 ? 239.290 147.790 210.081 1.00 73.37  ? 288 TYR C CD2   1 
ATOM   4986 C CE1   . TYR B 2 285 ? 236.725 147.962 209.113 1.00 73.37  ? 288 TYR C CE1   1 
ATOM   4987 C CE2   . TYR B 2 285 ? 238.825 148.984 209.596 1.00 73.37  ? 288 TYR C CE2   1 
ATOM   4988 C CZ    . TYR B 2 285 ? 237.543 149.066 209.113 1.00 73.37  ? 288 TYR C CZ    1 
ATOM   4989 O OH    . TYR B 2 285 ? 237.078 150.264 208.628 1.00 73.37  ? 288 TYR C OH    1 
ATOM   4990 N N     . GLN B 2 286 ? 240.414 144.320 213.414 1.00 78.44  ? 289 GLN C N     1 
ATOM   4991 C CA    . GLN B 2 286 ? 241.186 143.320 214.143 1.00 78.44  ? 289 GLN C CA    1 
ATOM   4992 C C     . GLN B 2 286 ? 240.307 142.578 215.138 1.00 78.44  ? 289 GLN C C     1 
ATOM   4993 O O     . GLN B 2 286 ? 240.250 141.343 215.134 1.00 78.44  ? 289 GLN C O     1 
ATOM   4994 C CB    . GLN B 2 286 ? 242.363 143.980 214.857 1.00 78.44  ? 289 GLN C CB    1 
ATOM   4995 C CG    . GLN B 2 286 ? 243.492 144.383 213.941 1.00 78.44  ? 289 GLN C CG    1 
ATOM   4996 C CD    . GLN B 2 286 ? 244.728 144.797 214.703 1.00 78.44  ? 289 GLN C CD    1 
ATOM   4997 O OE1   . GLN B 2 286 ? 244.833 144.566 215.906 1.00 78.44  ? 289 GLN C OE1   1 
ATOM   4998 N NE2   . GLN B 2 286 ? 245.672 145.414 214.008 1.00 78.44  ? 289 GLN C NE2   1 
ATOM   4999 N N     . ILE B 2 287 ? 239.612 143.321 216.002 1.00 75.61  ? 290 ILE C N     1 
ATOM   5000 C CA    . ILE B 2 287 ? 238.686 142.707 216.948 1.00 75.61  ? 290 ILE C CA    1 
ATOM   5001 C C     . ILE B 2 287 ? 237.610 141.930 216.207 1.00 75.61  ? 290 ILE C C     1 
ATOM   5002 O O     . ILE B 2 287 ? 237.206 140.839 216.627 1.00 75.61  ? 290 ILE C O     1 
ATOM   5003 C CB    . ILE B 2 287 ? 238.066 143.783 217.858 1.00 75.61  ? 290 ILE C CB    1 
ATOM   5004 C CG1   . ILE B 2 287 ? 239.132 144.430 218.738 1.00 75.61  ? 290 ILE C CG1   1 
ATOM   5005 C CG2   . ILE B 2 287 ? 236.964 143.194 218.715 1.00 75.61  ? 290 ILE C CG2   1 
ATOM   5006 C CD1   . ILE B 2 287 ? 238.613 145.596 219.535 1.00 75.61  ? 290 ILE C CD1   1 
ATOM   5007 N N     . LEU B 2 288 ? 237.142 142.471 215.088 1.00 78.22  ? 291 LEU C N     1 
ATOM   5008 C CA    . LEU B 2 288 ? 235.975 141.953 214.393 1.00 78.22  ? 291 LEU C CA    1 
ATOM   5009 C C     . LEU B 2 288 ? 236.302 140.788 213.465 1.00 78.22  ? 291 LEU C C     1 
ATOM   5010 O O     . LEU B 2 288 ? 235.383 140.188 212.898 1.00 78.22  ? 291 LEU C O     1 
ATOM   5011 C CB    . LEU B 2 288 ? 235.332 143.106 213.625 1.00 78.22  ? 291 LEU C CB    1 
ATOM   5012 C CG    . LEU B 2 288 ? 233.931 142.985 213.065 1.00 78.22  ? 291 LEU C CG    1 
ATOM   5013 C CD1   . LEU B 2 288 ? 233.000 142.719 214.207 1.00 78.22  ? 291 LEU C CD1   1 
ATOM   5014 C CD2   . LEU B 2 288 ? 233.580 144.295 212.422 1.00 78.22  ? 291 LEU C CD2   1 
ATOM   5015 N N     . SER B 2 289 ? 237.584 140.449 213.310 1.00 83.58  ? 292 SER C N     1 
ATOM   5016 C CA    . SER B 2 289 ? 238.034 139.331 212.487 1.00 83.58  ? 292 SER C CA    1 
ATOM   5017 C C     . SER B 2 289 ? 237.676 137.973 213.069 1.00 83.58  ? 292 SER C C     1 
ATOM   5018 O O     . SER B 2 289 ? 238.016 136.958 212.452 1.00 83.58  ? 292 SER C O     1 
ATOM   5019 C CB    . SER B 2 289 ? 239.547 139.408 212.289 1.00 83.58  ? 292 SER C CB    1 
ATOM   5020 O OG    . SER B 2 289 ? 240.209 139.569 213.531 1.00 83.58  ? 292 SER C OG    1 
ATOM   5021 N N     . ASN B 2 290 ? 237.018 137.932 214.229 1.00 85.90  ? 293 ASN C N     1 
ATOM   5022 C CA    . ASN B 2 290 ? 236.603 136.686 214.874 1.00 85.90  ? 293 ASN C CA    1 
ATOM   5023 C C     . ASN B 2 290 ? 237.764 135.704 214.995 1.00 85.90  ? 293 ASN C C     1 
ATOM   5024 O O     . ASN B 2 290 ? 237.627 134.507 214.740 1.00 85.90  ? 293 ASN C O     1 
ATOM   5025 C CB    . ASN B 2 290 ? 235.427 136.048 214.134 1.00 85.90  ? 293 ASN C CB    1 
ATOM   5026 C CG    . ASN B 2 290 ? 234.746 134.961 214.949 1.00 85.90  ? 293 ASN C CG    1 
ATOM   5027 O OD1   . ASN B 2 290 ? 234.963 134.846 216.154 1.00 85.90  ? 293 ASN C OD1   1 
ATOM   5028 N ND2   . ASN B 2 290 ? 233.917 134.160 214.292 1.00 85.90  ? 293 ASN C ND2   1 
ATOM   5029 N N     . LYS B 2 291 ? 238.931 136.222 215.374 1.00 91.05  ? 294 LYS C N     1 
ATOM   5030 C CA    . LYS B 2 291 ? 240.059 135.348 215.673 1.00 91.05  ? 294 LYS C CA    1 
ATOM   5031 C C     . LYS B 2 291 ? 240.007 134.868 217.117 1.00 91.05  ? 294 LYS C C     1 
ATOM   5032 O O     . LYS B 2 291 ? 240.428 133.746 217.420 1.00 91.05  ? 294 LYS C O     1 
ATOM   5033 C CB    . LYS B 2 291 ? 241.373 136.074 215.388 1.00 91.05  ? 294 LYS C CB    1 
ATOM   5034 C CG    . LYS B 2 291 ? 242.621 135.290 215.755 1.00 91.05  ? 294 LYS C CG    1 
ATOM   5035 C CD    . LYS B 2 291 ? 242.817 134.076 214.859 1.00 91.05  ? 294 LYS C CD    1 
ATOM   5036 C CE    . LYS B 2 291 ? 244.271 133.623 214.862 1.00 91.05  ? 294 LYS C CE    1 
ATOM   5037 N NZ    . LYS B 2 291 ? 244.507 132.474 213.944 1.00 91.05  ? 294 LYS C NZ    1 
ATOM   5038 N N     . LYS B 2 292 ? 239.484 135.701 218.014 1.00 90.10  ? 295 LYS C N     1 
ATOM   5039 C CA    . LYS B 2 292 ? 239.301 135.346 219.416 1.00 90.10  ? 295 LYS C CA    1 
ATOM   5040 C C     . LYS B 2 292 ? 237.818 135.424 219.750 1.00 90.10  ? 295 LYS C C     1 
ATOM   5041 O O     . LYS B 2 292 ? 237.263 136.528 219.851 1.00 90.10  ? 295 LYS C O     1 
ATOM   5042 C CB    . LYS B 2 292 ? 240.106 136.285 220.318 1.00 90.10  ? 295 LYS C CB    1 
ATOM   5043 C CG    . LYS B 2 292 ? 241.514 136.561 219.816 1.00 90.10  ? 295 LYS C CG    1 
ATOM   5044 C CD    . LYS B 2 292 ? 242.135 137.746 220.531 1.00 90.10  ? 295 LYS C CD    1 
ATOM   5045 C CE    . LYS B 2 292 ? 241.959 137.639 222.033 1.00 90.10  ? 295 LYS C CE    1 
ATOM   5046 N NZ    . LYS B 2 292 ? 242.513 136.365 222.566 1.00 90.10  ? 295 LYS C NZ    1 
ATOM   5047 N N     . PRO B 2 293 ? 237.130 134.295 219.919 1.00 90.84  ? 296 PRO C N     1 
ATOM   5048 C CA    . PRO B 2 293 ? 235.680 134.350 220.177 1.00 90.84  ? 296 PRO C CA    1 
ATOM   5049 C C     . PRO B 2 293 ? 235.316 134.973 221.512 1.00 90.84  ? 296 PRO C C     1 
ATOM   5050 O O     . PRO B 2 293 ? 234.173 135.419 221.680 1.00 90.84  ? 296 PRO C O     1 
ATOM   5051 C CB    . PRO B 2 293 ? 235.257 132.875 220.117 1.00 90.84  ? 296 PRO C CB    1 
ATOM   5052 C CG    . PRO B 2 293 ? 236.363 132.180 219.372 1.00 90.84  ? 296 PRO C CG    1 
ATOM   5053 C CD    . PRO B 2 293 ? 237.610 132.915 219.744 1.00 90.84  ? 296 PRO C CD    1 
ATOM   5054 N N     . GLU B 2 294 ? 236.247 135.017 222.466 1.00 90.00  ? 297 GLU C N     1 
ATOM   5055 C CA    . GLU B 2 294 ? 235.949 135.597 223.771 1.00 90.00  ? 297 GLU C CA    1 
ATOM   5056 C C     . GLU B 2 294 ? 235.521 137.054 223.649 1.00 90.00  ? 297 GLU C C     1 
ATOM   5057 O O     . GLU B 2 294 ? 234.583 137.493 224.324 1.00 90.00  ? 297 GLU C O     1 
ATOM   5058 C CB    . GLU B 2 294 ? 237.166 135.470 224.687 1.00 90.00  ? 297 GLU C CB    1 
ATOM   5059 C CG    . GLU B 2 294 ? 238.468 135.930 224.051 1.00 90.00  ? 297 GLU C CG    1 
ATOM   5060 C CD    . GLU B 2 294 ? 239.644 135.830 224.997 1.00 90.00  ? 297 GLU C CD    1 
ATOM   5061 O OE1   . GLU B 2 294 ? 239.415 135.651 226.210 1.00 90.00  ? 297 GLU C OE1   1 
ATOM   5062 O OE2   . GLU B 2 294 ? 240.797 135.929 224.529 1.00 90.00  ? 297 GLU C OE2   1 
ATOM   5063 N N     . LEU B 2 295 ? 236.195 137.819 222.790 1.00 83.96  ? 298 LEU C N     1 
ATOM   5064 C CA    . LEU B 2 295 ? 235.853 139.227 222.629 1.00 83.96  ? 298 LEU C CA    1 
ATOM   5065 C C     . LEU B 2 295 ? 234.470 139.390 222.013 1.00 83.96  ? 298 LEU C C     1 
ATOM   5066 O O     . LEU B 2 295 ? 233.614 140.093 222.561 1.00 83.96  ? 298 LEU C O     1 
ATOM   5067 C CB    . LEU B 2 295 ? 236.911 139.925 221.779 1.00 83.96  ? 298 LEU C CB    1 
ATOM   5068 C CG    . LEU B 2 295 ? 238.310 139.848 222.380 1.00 83.96  ? 298 LEU C CG    1 
ATOM   5069 C CD1   . LEU B 2 295 ? 239.341 140.423 221.430 1.00 83.96  ? 298 LEU C CD1   1 
ATOM   5070 C CD2   . LEU B 2 295 ? 238.331 140.563 223.711 1.00 83.96  ? 298 LEU C CD2   1 
ATOM   5071 N N     . LEU B 2 296 ? 234.230 138.740 220.875 1.00 83.90  ? 299 LEU C N     1 
ATOM   5072 C CA    . LEU B 2 296 ? 232.935 138.849 220.218 1.00 83.90  ? 299 LEU C CA    1 
ATOM   5073 C C     . LEU B 2 296 ? 231.807 138.250 221.044 1.00 83.90  ? 299 LEU C C     1 
ATOM   5074 O O     . LEU B 2 296 ? 230.638 138.500 220.733 1.00 83.90  ? 299 LEU C O     1 
ATOM   5075 C CB    . LEU B 2 296 ? 232.979 138.182 218.841 1.00 83.90  ? 299 LEU C CB    1 
ATOM   5076 C CG    . LEU B 2 296 ? 233.799 138.879 217.753 1.00 83.90  ? 299 LEU C CG    1 
ATOM   5077 C CD1   . LEU B 2 296 ? 235.285 138.584 217.887 1.00 83.90  ? 299 LEU C CD1   1 
ATOM   5078 C CD2   . LEU B 2 296 ? 233.296 138.480 216.380 1.00 83.90  ? 299 LEU C CD2   1 
ATOM   5079 N N     . ASP B 2 297 ? 232.119 137.468 222.075 1.00 86.20  ? 300 ASP C N     1 
ATOM   5080 C CA    . ASP B 2 297 ? 231.092 137.030 223.011 1.00 86.20  ? 300 ASP C CA    1 
ATOM   5081 C C     . ASP B 2 297 ? 230.914 137.999 224.168 1.00 86.20  ? 300 ASP C C     1 
ATOM   5082 O O     . ASP B 2 297 ? 229.817 138.088 224.731 1.00 86.20  ? 300 ASP C O     1 
ATOM   5083 C CB    . ASP B 2 297 ? 231.429 135.640 223.555 1.00 86.20  ? 300 ASP C CB    1 
ATOM   5084 C CG    . ASP B 2 297 ? 230.356 135.100 224.475 1.00 86.20  ? 300 ASP C CG    1 
ATOM   5085 O OD1   . ASP B 2 297 ? 229.165 135.168 224.105 1.00 86.20  ? 300 ASP C OD1   1 
ATOM   5086 O OD2   . ASP B 2 297 ? 230.702 134.604 225.567 1.00 86.20  ? 300 ASP C OD2   1 
ATOM   5087 N N     . MET B 2 298 ? 231.966 138.729 224.533 1.00 82.89  ? 301 MET C N     1 
ATOM   5088 C CA    . MET B 2 298 ? 231.890 139.702 225.613 1.00 82.89  ? 301 MET C CA    1 
ATOM   5089 C C     . MET B 2 298 ? 231.438 141.074 225.135 1.00 82.89  ? 301 MET C C     1 
ATOM   5090 O O     . MET B 2 298 ? 230.730 141.773 225.868 1.00 82.89  ? 301 MET C O     1 
ATOM   5091 C CB    . MET B 2 298 ? 233.250 139.822 226.305 1.00 82.89  ? 301 MET C CB    1 
ATOM   5092 C CG    . MET B 2 298 ? 233.312 140.869 227.402 1.00 82.89  ? 301 MET C CG    1 
ATOM   5093 S SD    . MET B 2 298 ? 235.002 141.236 227.905 1.00 82.89  ? 301 MET C SD    1 
ATOM   5094 C CE    . MET B 2 298 ? 235.689 141.848 226.370 1.00 82.89  ? 301 MET C CE    1 
ATOM   5095 N N     . LEU B 2 299 ? 231.819 141.474 223.924 1.00 76.67  ? 302 LEU C N     1 
ATOM   5096 C CA    . LEU B 2 299 ? 231.415 142.765 223.387 1.00 76.67  ? 302 LEU C CA    1 
ATOM   5097 C C     . LEU B 2 299 ? 229.976 142.784 222.895 1.00 76.67  ? 302 LEU C C     1 
ATOM   5098 O O     . LEU B 2 299 ? 229.489 143.853 222.516 1.00 76.67  ? 302 LEU C O     1 
ATOM   5099 C CB    . LEU B 2 299 ? 232.337 143.178 222.238 1.00 76.67  ? 302 LEU C CB    1 
ATOM   5100 C CG    . LEU B 2 299 ? 233.815 143.402 222.538 1.00 76.67  ? 302 LEU C CG    1 
ATOM   5101 C CD1   . LEU B 2 299 ? 234.436 144.239 221.442 1.00 76.67  ? 302 LEU C CD1   1 
ATOM   5102 C CD2   . LEU B 2 299 ? 233.986 144.068 223.881 1.00 76.67  ? 302 LEU C CD2   1 
ATOM   5103 N N     . LEU B 2 300 ? 229.291 141.641 222.895 1.00 75.71  ? 303 LEU C N     1 
ATOM   5104 C CA    . LEU B 2 300 ? 227.952 141.533 222.319 1.00 75.71  ? 303 LEU C CA    1 
ATOM   5105 C C     . LEU B 2 300 ? 227.943 142.037 220.880 1.00 75.71  ? 303 LEU C C     1 
ATOM   5106 O O     . LEU B 2 300 ? 227.061 142.788 220.462 1.00 75.71  ? 303 LEU C O     1 
ATOM   5107 C CB    . LEU B 2 300 ? 226.919 142.271 223.169 1.00 75.71  ? 303 LEU C CB    1 
ATOM   5108 C CG    . LEU B 2 300 ? 226.372 141.496 224.368 1.00 75.71  ? 303 LEU C CG    1 
ATOM   5109 C CD1   . LEU B 2 300 ? 227.366 141.488 225.509 1.00 75.71  ? 303 LEU C CD1   1 
ATOM   5110 C CD2   . LEU B 2 300 ? 225.047 142.080 224.820 1.00 75.71  ? 303 LEU C CD2   1 
ATOM   5111 N N     . VAL B 2 301 ? 228.948 141.620 220.120 1.00 76.81  ? 304 VAL C N     1 
ATOM   5112 C CA    . VAL B 2 301 ? 229.128 142.040 218.740 1.00 76.81  ? 304 VAL C CA    1 
ATOM   5113 C C     . VAL B 2 301 ? 229.113 140.799 217.861 1.00 76.81  ? 304 VAL C C     1 
ATOM   5114 O O     . VAL B 2 301 ? 229.491 139.705 218.292 1.00 76.81  ? 304 VAL C O     1 
ATOM   5115 C CB    . VAL B 2 301 ? 230.443 142.836 218.567 1.00 76.81  ? 304 VAL C CB    1 
ATOM   5116 C CG1   . VAL B 2 301 ? 231.646 141.935 218.755 1.00 76.81  ? 304 VAL C CG1   1 
ATOM   5117 C CG2   . VAL B 2 301 ? 230.501 143.527 217.228 1.00 76.81  ? 304 VAL C CG2   1 
ATOM   5118 N N     . THR B 2 302 ? 228.650 140.969 216.627 1.00 80.74  ? 305 THR C N     1 
ATOM   5119 C CA    . THR B 2 302 ? 228.672 139.898 215.644 1.00 80.74  ? 305 THR C CA    1 
ATOM   5120 C C     . THR B 2 302 ? 230.009 139.932 214.907 1.00 80.74  ? 305 THR C C     1 
ATOM   5121 O O     . THR B 2 302 ? 230.940 140.636 215.304 1.00 80.74  ? 305 THR C O     1 
ATOM   5122 C CB    . THR B 2 302 ? 227.483 140.022 214.696 1.00 80.74  ? 305 THR C CB    1 
ATOM   5123 O OG1   . THR B 2 302 ? 227.459 141.336 214.125 1.00 80.74  ? 305 THR C OG1   1 
ATOM   5124 C CG2   . THR B 2 302 ? 226.184 139.774 215.444 1.00 80.74  ? 305 THR C CG2   1 
ATOM   5125 N N     . ASN B 2 303 ? 230.130 139.158 213.833 1.00 82.02  ? 306 ASN C N     1 
ATOM   5126 C CA    . ASN B 2 303 ? 231.366 139.095 213.070 1.00 82.02  ? 306 ASN C CA    1 
ATOM   5127 C C     . ASN B 2 303 ? 231.244 139.689 211.674 1.00 82.02  ? 306 ASN C C     1 
ATOM   5128 O O     . ASN B 2 303 ? 232.218 139.653 210.914 1.00 82.02  ? 306 ASN C O     1 
ATOM   5129 C CB    . ASN B 2 303 ? 231.861 137.645 212.983 1.00 82.02  ? 306 ASN C CB    1 
ATOM   5130 C CG    . ASN B 2 303 ? 230.847 136.711 212.351 1.00 82.02  ? 306 ASN C CG    1 
ATOM   5131 O OD1   . ASN B 2 303 ? 230.200 137.045 211.358 1.00 82.02  ? 306 ASN C OD1   1 
ATOM   5132 N ND2   . ASN B 2 303 ? 230.708 135.524 212.925 1.00 82.02  ? 306 ASN C ND2   1 
ATOM   5133 N N     . ASN B 2 304 ? 230.082 140.228 211.312 1.00 81.68  ? 307 ASN C N     1 
ATOM   5134 C CA    . ASN B 2 304 ? 229.889 140.821 209.997 1.00 81.68  ? 307 ASN C CA    1 
ATOM   5135 C C     . ASN B 2 304 ? 230.153 142.317 210.092 1.00 81.68  ? 307 ASN C C     1 
ATOM   5136 O O     . ASN B 2 304 ? 229.382 143.027 210.754 1.00 81.68  ? 307 ASN C O     1 
ATOM   5137 C CB    . ASN B 2 304 ? 228.478 140.557 209.495 1.00 81.68  ? 307 ASN C CB    1 
ATOM   5138 C CG    . ASN B 2 304 ? 228.261 141.040 208.076 1.00 81.68  ? 307 ASN C CG    1 
ATOM   5139 O OD1   . ASN B 2 304 ? 229.195 141.469 207.402 1.00 81.68  ? 307 ASN C OD1   1 
ATOM   5140 N ND2   . ASN B 2 304 ? 227.020 140.967 207.613 1.00 81.68  ? 307 ASN C ND2   1 
ATOM   5141 N N     . PRO B 2 305 ? 231.209 142.840 209.466 1.00 78.90  ? 308 PRO C N     1 
ATOM   5142 C CA    . PRO B 2 305 ? 231.494 144.277 209.590 1.00 78.90  ? 308 PRO C CA    1 
ATOM   5143 C C     . PRO B 2 305 ? 230.444 145.170 208.960 1.00 78.90  ? 308 PRO C C     1 
ATOM   5144 O O     . PRO B 2 305 ? 230.416 146.367 209.265 1.00 78.90  ? 308 PRO C O     1 
ATOM   5145 C CB    . PRO B 2 305 ? 232.844 144.431 208.879 1.00 78.90  ? 308 PRO C CB    1 
ATOM   5146 C CG    . PRO B 2 305 ? 233.434 143.066 208.885 1.00 78.90  ? 308 PRO C CG    1 
ATOM   5147 C CD    . PRO B 2 305 ? 232.279 142.128 208.754 1.00 78.90  ? 308 PRO C CD    1 
ATOM   5148 N N     . TYR B 2 306 ? 229.586 144.641 208.097 1.00 80.38  ? 309 TYR C N     1 
ATOM   5149 C CA    . TYR B 2 306 ? 228.562 145.453 207.457 1.00 80.38  ? 309 TYR C CA    1 
ATOM   5150 C C     . TYR B 2 306 ? 227.357 145.702 208.352 1.00 80.38  ? 309 TYR C C     1 
ATOM   5151 O O     . TYR B 2 306 ? 226.357 146.246 207.877 1.00 80.38  ? 309 TYR C O     1 
ATOM   5152 C CB    . TYR B 2 306 ? 228.113 144.799 206.150 1.00 80.38  ? 309 TYR C CB    1 
ATOM   5153 C CG    . TYR B 2 306 ? 229.108 144.968 205.031 1.00 80.38  ? 309 TYR C CG    1 
ATOM   5154 C CD1   . TYR B 2 306 ? 229.337 146.214 204.468 1.00 80.38  ? 309 TYR C CD1   1 
ATOM   5155 C CD2   . TYR B 2 306 ? 229.822 143.886 204.544 1.00 80.38  ? 309 TYR C CD2   1 
ATOM   5156 C CE1   . TYR B 2 306 ? 230.247 146.376 203.448 1.00 80.38  ? 309 TYR C CE1   1 
ATOM   5157 C CE2   . TYR B 2 306 ? 230.735 144.037 203.525 1.00 80.38  ? 309 TYR C CE2   1 
ATOM   5158 C CZ    . TYR B 2 306 ? 230.943 145.285 202.980 1.00 80.38  ? 309 TYR C CZ    1 
ATOM   5159 O OH    . TYR B 2 306 ? 231.852 145.441 201.962 1.00 80.38  ? 309 TYR C OH    1 
ATOM   5160 N N     . ASP B 2 307 ? 227.428 145.323 209.624 1.00 79.60  ? 310 ASP C N     1 
ATOM   5161 C CA    . ASP B 2 307 ? 226.329 145.539 210.551 1.00 79.60  ? 310 ASP C CA    1 
ATOM   5162 C C     . ASP B 2 307 ? 226.448 146.842 211.327 1.00 79.60  ? 310 ASP C C     1 
ATOM   5163 O O     . ASP B 2 307 ? 225.484 147.239 211.989 1.00 79.60  ? 310 ASP C O     1 
ATOM   5164 C CB    . ASP B 2 307 ? 226.237 144.375 211.542 1.00 79.60  ? 310 ASP C CB    1 
ATOM   5165 C CG    . ASP B 2 307 ? 225.671 143.123 210.915 1.00 79.60  ? 310 ASP C CG    1 
ATOM   5166 O OD1   . ASP B 2 307 ? 225.586 143.068 209.671 1.00 79.60  ? 310 ASP C OD1   1 
ATOM   5167 O OD2   . ASP B 2 307 ? 225.309 142.194 211.665 1.00 79.60  ? 310 ASP C OD2   1 
ATOM   5168 N N     . TYR B 2 308 ? 227.593 147.515 211.259 1.00 74.80  ? 311 TYR C N     1 
ATOM   5169 C CA    . TYR B 2 308 ? 227.876 148.667 212.102 1.00 74.80  ? 311 TYR C CA    1 
ATOM   5170 C C     . TYR B 2 308 ? 228.251 149.841 211.215 1.00 74.80  ? 311 TYR C C     1 
ATOM   5171 O O     . TYR B 2 308 ? 229.143 149.724 210.370 1.00 74.80  ? 311 TYR C O     1 
ATOM   5172 C CB    . TYR B 2 308 ? 228.981 148.331 213.105 1.00 74.80  ? 311 TYR C CB    1 
ATOM   5173 C CG    . TYR B 2 308 ? 228.692 147.027 213.810 1.00 74.80  ? 311 TYR C CG    1 
ATOM   5174 C CD1   . TYR B 2 308 ? 227.892 146.992 214.942 1.00 74.80  ? 311 TYR C CD1   1 
ATOM   5175 C CD2   . TYR B 2 308 ? 229.181 145.826 213.321 1.00 74.80  ? 311 TYR C CD2   1 
ATOM   5176 C CE1   . TYR B 2 308 ? 227.606 145.803 215.575 1.00 74.80  ? 311 TYR C CE1   1 
ATOM   5177 C CE2   . TYR B 2 308 ? 228.898 144.634 213.948 1.00 74.80  ? 311 TYR C CE2   1 
ATOM   5178 C CZ    . TYR B 2 308 ? 228.110 144.629 215.074 1.00 74.80  ? 311 TYR C CZ    1 
ATOM   5179 O OH    . TYR B 2 308 ? 227.823 143.442 215.704 1.00 74.80  ? 311 TYR C OH    1 
ATOM   5180 N N     . ALA B 2 309 ? 227.565 150.969 211.405 1.00 73.25  ? 312 ALA C N     1 
ATOM   5181 C CA    . ALA B 2 309 ? 227.684 152.087 210.479 1.00 73.25  ? 312 ALA C CA    1 
ATOM   5182 C C     . ALA B 2 309 ? 229.005 152.829 210.606 1.00 73.25  ? 312 ALA C C     1 
ATOM   5183 O O     . ALA B 2 309 ? 229.433 153.469 209.642 1.00 73.25  ? 312 ALA C O     1 
ATOM   5184 C CB    . ALA B 2 309 ? 226.526 153.060 210.689 1.00 73.25  ? 312 ALA C CB    1 
ATOM   5185 N N     . PHE B 2 310 ? 229.656 152.772 211.764 1.00 70.69  ? 313 PHE C N     1 
ATOM   5186 C CA    . PHE B 2 310 ? 230.897 153.509 211.948 1.00 70.69  ? 313 PHE C CA    1 
ATOM   5187 C C     . PHE B 2 310 ? 232.101 152.825 211.318 1.00 70.69  ? 313 PHE C C     1 
ATOM   5188 O O     . PHE B 2 310 ? 233.127 153.482 211.119 1.00 70.69  ? 313 PHE C O     1 
ATOM   5189 C CB    . PHE B 2 310 ? 231.163 153.732 213.437 1.00 70.69  ? 313 PHE C CB    1 
ATOM   5190 C CG    . PHE B 2 310 ? 230.449 154.920 214.011 1.00 70.69  ? 313 PHE C CG    1 
ATOM   5191 C CD1   . PHE B 2 310 ? 229.721 155.767 213.198 1.00 70.69  ? 313 PHE C CD1   1 
ATOM   5192 C CD2   . PHE B 2 310 ? 230.513 155.195 215.363 1.00 70.69  ? 313 PHE C CD2   1 
ATOM   5193 C CE1   . PHE B 2 310 ? 229.068 156.857 213.724 1.00 70.69  ? 313 PHE C CE1   1 
ATOM   5194 C CE2   . PHE B 2 310 ? 229.862 156.283 215.891 1.00 70.69  ? 313 PHE C CE2   1 
ATOM   5195 C CZ    . PHE B 2 310 ? 229.139 157.115 215.072 1.00 70.69  ? 313 PHE C CZ    1 
ATOM   5196 N N     . VAL B 2 311 ? 232.007 151.540 210.994 1.00 72.14  ? 314 VAL C N     1 
ATOM   5197 C CA    . VAL B 2 311 ? 233.153 150.797 210.492 1.00 72.14  ? 314 VAL C CA    1 
ATOM   5198 C C     . VAL B 2 311 ? 233.034 150.430 209.018 1.00 72.14  ? 314 VAL C C     1 
ATOM   5199 O O     . VAL B 2 311 ? 234.058 150.104 208.399 1.00 72.14  ? 314 VAL C O     1 
ATOM   5200 C CB    . VAL B 2 311 ? 233.405 149.529 211.333 1.00 72.14  ? 314 VAL C CB    1 
ATOM   5201 C CG1   . VAL B 2 311 ? 233.693 149.903 212.768 1.00 72.14  ? 314 VAL C CG1   1 
ATOM   5202 C CG2   . VAL B 2 311 ? 232.215 148.599 211.257 1.00 72.14  ? 314 VAL C CG2   1 
ATOM   5203 N N     . SER B 2 312 ? 231.840 150.473 208.435 1.00 75.41  ? 315 SER C N     1 
ATOM   5204 C CA    . SER B 2 312 ? 231.606 149.975 207.085 1.00 75.41  ? 315 SER C CA    1 
ATOM   5205 C C     . SER B 2 312 ? 231.065 151.051 206.150 1.00 75.41  ? 315 SER C C     1 
ATOM   5206 O O     . SER B 2 312 ? 230.146 150.807 205.370 1.00 75.41  ? 315 SER C O     1 
ATOM   5207 C CB    . SER B 2 312 ? 230.654 148.785 207.116 1.00 75.41  ? 315 SER C CB    1 
ATOM   5208 O OG    . SER B 2 312 ? 229.371 149.188 207.555 1.00 75.41  ? 315 SER C OG    1 
ATOM   5209 N N     . GLN B 2 313 ? 231.623 152.258 206.214 1.00 77.99  ? 316 GLN C N     1 
ATOM   5210 C CA    . GLN B 2 313 ? 231.237 153.277 205.244 1.00 77.99  ? 316 GLN C CA    1 
ATOM   5211 C C     . GLN B 2 313 ? 232.097 153.204 203.991 1.00 77.99  ? 316 GLN C C     1 
ATOM   5212 O O     . GLN B 2 313 ? 231.624 153.509 202.892 1.00 77.99  ? 316 GLN C O     1 
ATOM   5213 C CB    . GLN B 2 313 ? 231.317 154.667 205.870 1.00 77.99  ? 316 GLN C CB    1 
ATOM   5214 C CG    . GLN B 2 313 ? 230.241 154.925 206.897 1.00 77.99  ? 316 GLN C CG    1 
ATOM   5215 C CD    . GLN B 2 313 ? 230.418 156.250 207.590 1.00 77.99  ? 316 GLN C CD    1 
ATOM   5216 O OE1   . GLN B 2 313 ? 230.876 157.218 206.988 1.00 77.99  ? 316 GLN C OE1   1 
ATOM   5217 N NE2   . GLN B 2 313 ? 230.059 156.304 208.865 1.00 77.99  ? 316 GLN C NE2   1 
ATOM   5218 N N     . GLY B 2 314 ? 233.357 152.811 204.136 1.00 81.45  ? 317 GLY C N     1 
ATOM   5219 C CA    . GLY B 2 314 ? 234.198 152.562 202.986 1.00 81.45  ? 317 GLY C CA    1 
ATOM   5220 C C     . GLY B 2 314 ? 234.207 151.089 202.646 1.00 81.45  ? 317 GLY C C     1 
ATOM   5221 O O     . GLY B 2 314 ? 233.201 150.543 202.184 1.00 81.45  ? 317 GLY C O     1 
ATOM   5222 N N     . GLU B 2 315 ? 235.336 150.432 202.879 1.00 85.76  ? 318 GLU C N     1 
ATOM   5223 C CA    . GLU B 2 315 ? 235.469 148.999 202.685 1.00 85.76  ? 318 GLU C CA    1 
ATOM   5224 C C     . GLU B 2 315 ? 235.820 148.337 204.010 1.00 85.76  ? 318 GLU C C     1 
ATOM   5225 O O     . GLU B 2 315 ? 236.320 148.985 204.931 1.00 85.76  ? 318 GLU C O     1 
ATOM   5226 C CB    . GLU B 2 315 ? 236.525 148.688 201.625 1.00 85.76  ? 318 GLU C CB    1 
ATOM   5227 C CG    . GLU B 2 315 ? 237.907 149.189 201.962 1.00 85.76  ? 318 GLU C CG    1 
ATOM   5228 C CD    . GLU B 2 315 ? 238.881 148.958 200.834 1.00 85.76  ? 318 GLU C CD    1 
ATOM   5229 O OE1   . GLU B 2 315 ? 238.457 148.416 199.794 1.00 85.76  ? 318 GLU C OE1   1 
ATOM   5230 O OE2   . GLU B 2 315 ? 240.067 149.321 200.980 1.00 85.76  ? 318 GLU C OE2   1 
ATOM   5231 N N     . VAL B 2 316 ? 235.543 147.036 204.103 1.00 84.19  ? 319 VAL C N     1 
ATOM   5232 C CA    . VAL B 2 316 ? 235.685 146.317 205.365 1.00 84.19  ? 319 VAL C CA    1 
ATOM   5233 C C     . VAL B 2 316 ? 236.852 145.344 205.376 1.00 84.19  ? 319 VAL C C     1 
ATOM   5234 O O     . VAL B 2 316 ? 237.121 144.735 206.424 1.00 84.19  ? 319 VAL C O     1 
ATOM   5235 C CB    . VAL B 2 316 ? 234.393 145.555 205.720 1.00 84.19  ? 319 VAL C CB    1 
ATOM   5236 C CG1   . VAL B 2 316 ? 233.236 146.520 205.847 1.00 84.19  ? 319 VAL C CG1   1 
ATOM   5237 C CG2   . VAL B 2 316 ? 234.103 144.493 204.675 1.00 84.19  ? 319 VAL C CG2   1 
ATOM   5238 N N     . SER B 2 317 ? 237.545 145.162 204.256 1.00 89.38  ? 320 SER C N     1 
ATOM   5239 C CA    . SER B 2 317 ? 238.626 144.191 204.204 1.00 89.38  ? 320 SER C CA    1 
ATOM   5240 C C     . SER B 2 317 ? 239.596 144.567 203.099 1.00 89.38  ? 320 SER C C     1 
ATOM   5241 O O     . SER B 2 317 ? 239.184 145.004 202.022 1.00 89.38  ? 320 SER C O     1 
ATOM   5242 C CB    . SER B 2 317 ? 238.092 142.771 203.977 1.00 89.38  ? 320 SER C CB    1 
ATOM   5243 O OG    . SER B 2 317 ? 237.374 142.688 202.760 1.00 89.38  ? 320 SER C OG    1 
ATOM   5244 N N     . VAL B 2 318 ? 240.883 144.403 203.381 1.00 92.40  ? 321 VAL C N     1 
ATOM   5245 C CA    . VAL B 2 318 ? 241.937 144.570 202.392 1.00 92.40  ? 321 VAL C CA    1 
ATOM   5246 C C     . VAL B 2 318 ? 242.771 143.299 202.374 1.00 92.40  ? 321 VAL C C     1 
ATOM   5247 O O     . VAL B 2 318 ? 242.861 142.576 203.372 1.00 92.40  ? 321 VAL C O     1 
ATOM   5248 C CB    . VAL B 2 318 ? 242.813 145.808 202.675 1.00 92.40  ? 321 VAL C CB    1 
ATOM   5249 C CG1   . VAL B 2 318 ? 241.963 147.063 202.676 1.00 92.40  ? 321 VAL C CG1   1 
ATOM   5250 C CG2   . VAL B 2 318 ? 243.535 145.656 203.997 1.00 92.40  ? 321 VAL C CG2   1 
ATOM   5251 N N     . ALA B 2 319 ? 243.371 143.019 201.221 1.00 99.08  ? 322 ALA C N     1 
ATOM   5252 C CA    . ALA B 2 319 ? 244.137 141.797 201.026 1.00 99.08  ? 322 ALA C CA    1 
ATOM   5253 C C     . ALA B 2 319 ? 245.634 141.991 201.223 1.00 99.08  ? 322 ALA C C     1 
ATOM   5254 O O     . ALA B 2 319 ? 246.393 141.031 201.060 1.00 99.08  ? 322 ALA C O     1 
ATOM   5255 C CB    . ALA B 2 319 ? 243.871 141.226 199.630 1.00 99.08  ? 322 ALA C CB    1 
ATOM   5256 N N     . SER B 2 320 ? 246.076 143.197 201.568 1.00 98.03  ? 323 SER C N     1 
ATOM   5257 C CA    . SER B 2 320 ? 247.488 143.447 201.818 1.00 98.03  ? 323 SER C CA    1 
ATOM   5258 C C     . SER B 2 320 ? 247.906 143.140 203.248 1.00 98.03  ? 323 SER C C     1 
ATOM   5259 O O     . SER B 2 320 ? 249.106 143.010 203.509 1.00 98.03  ? 323 SER C O     1 
ATOM   5260 C CB    . SER B 2 320 ? 247.829 144.903 201.498 1.00 98.03  ? 323 SER C CB    1 
ATOM   5261 O OG    . SER B 2 320 ? 249.188 145.177 201.785 1.00 98.03  ? 323 SER C OG    1 
ATOM   5262 N N     . ILE B 2 321 ? 246.956 143.015 204.171 1.00 97.98  ? 324 ILE C N     1 
ATOM   5263 C CA    . ILE B 2 321 ? 247.245 142.686 205.564 1.00 97.98  ? 324 ILE C CA    1 
ATOM   5264 C C     . ILE B 2 321 ? 246.151 141.761 206.072 1.00 97.98  ? 324 ILE C C     1 
ATOM   5265 O O     . ILE B 2 321 ? 244.962 141.990 205.831 1.00 97.98  ? 324 ILE C O     1 
ATOM   5266 C CB    . ILE B 2 321 ? 247.358 143.948 206.454 1.00 97.98  ? 324 ILE C CB    1 
ATOM   5267 C CG1   . ILE B 2 321 ? 246.065 144.765 206.417 1.00 97.98  ? 324 ILE C CG1   1 
ATOM   5268 C CG2   . ILE B 2 321 ? 248.553 144.808 206.058 1.00 97.98  ? 324 ILE C CG2   1 
ATOM   5269 C CD1   . ILE B 2 321 ? 246.017 145.871 207.438 1.00 97.98  ? 324 ILE C CD1   1 
ATOM   5270 N N     . ASP B 2 322 ? 246.558 140.695 206.751 1.00 99.36  ? 325 ASP C N     1 
ATOM   5271 C CA    . ASP B 2 322 ? 245.619 139.827 207.441 1.00 99.36  ? 325 ASP C CA    1 
ATOM   5272 C C     . ASP B 2 322 ? 245.372 140.369 208.841 1.00 99.36  ? 325 ASP C C     1 
ATOM   5273 O O     . ASP B 2 322 ? 246.293 140.832 209.517 1.00 99.36  ? 325 ASP C O     1 
ATOM   5274 C CB    . ASP B 2 322 ? 246.147 138.394 207.517 1.00 99.36  ? 325 ASP C CB    1 
ATOM   5275 C CG    . ASP B 2 322 ? 245.099 137.409 207.994 1.00 99.36  ? 325 ASP C CG    1 
ATOM   5276 O OD1   . ASP B 2 322 ? 244.713 136.521 207.203 1.00 99.36  ? 325 ASP C OD1   1 
ATOM   5277 O OD2   . ASP B 2 322 ? 244.651 137.520 209.155 1.00 99.36  ? 325 ASP C OD2   1 
ATOM   5278 N N     . ASP B 2 323 ? 244.118 140.298 209.279 1.00 93.63  ? 326 ASP C N     1 
ATOM   5279 C CA    . ASP B 2 323 ? 243.724 140.922 210.534 1.00 93.63  ? 326 ASP C CA    1 
ATOM   5280 C C     . ASP B 2 323 ? 243.931 140.028 211.747 1.00 93.63  ? 326 ASP C C     1 
ATOM   5281 O O     . ASP B 2 323 ? 244.097 140.549 212.853 1.00 93.63  ? 326 ASP C O     1 
ATOM   5282 C CB    . ASP B 2 323 ? 242.257 141.352 210.468 1.00 93.63  ? 326 ASP C CB    1 
ATOM   5283 C CG    . ASP B 2 323 ? 242.023 142.463 209.466 1.00 93.63  ? 326 ASP C CG    1 
ATOM   5284 O OD1   . ASP B 2 323 ? 242.713 143.500 209.558 1.00 93.63  ? 326 ASP C OD1   1 
ATOM   5285 O OD2   . ASP B 2 323 ? 241.152 142.299 208.585 1.00 93.63  ? 326 ASP C OD2   1 
ATOM   5286 N N     . SER B 2 324 ? 243.934 138.706 211.571 1.00 94.17  ? 327 SER C N     1 
ATOM   5287 C CA    . SER B 2 324 ? 244.056 137.809 212.717 1.00 94.17  ? 327 SER C CA    1 
ATOM   5288 C C     . SER B 2 324 ? 245.445 137.889 213.341 1.00 94.17  ? 327 SER C C     1 
ATOM   5289 O O     . SER B 2 324 ? 245.585 137.969 214.569 1.00 94.17  ? 327 SER C O     1 
ATOM   5290 C CB    . SER B 2 324 ? 243.737 136.378 212.290 1.00 94.17  ? 327 SER C CB    1 
ATOM   5291 O OG    . SER B 2 324 ? 242.590 136.337 211.460 1.00 94.17  ? 327 SER C OG    1 
ATOM   5292 N N     . GLU B 2 325 ? 246.489 137.871 212.512 1.00 97.22  ? 328 GLU C N     1 
ATOM   5293 C CA    . GLU B 2 325 ? 247.838 137.970 213.055 1.00 97.22  ? 328 GLU C CA    1 
ATOM   5294 C C     . GLU B 2 325 ? 248.115 139.356 213.618 1.00 97.22  ? 328 GLU C C     1 
ATOM   5295 O O     . GLU B 2 325 ? 248.830 139.482 214.617 1.00 97.22  ? 328 GLU C O     1 
ATOM   5296 C CB    . GLU B 2 325 ? 248.869 137.598 211.990 1.00 97.22  ? 328 GLU C CB    1 
ATOM   5297 C CG    . GLU B 2 325 ? 248.917 136.108 211.683 1.00 97.22  ? 328 GLU C CG    1 
ATOM   5298 C CD    . GLU B 2 325 ? 247.830 135.665 210.727 1.00 97.22  ? 328 GLU C CD    1 
ATOM   5299 O OE1   . GLU B 2 325 ? 247.082 136.532 210.226 1.00 97.22  ? 328 GLU C OE1   1 
ATOM   5300 O OE2   . GLU B 2 325 ? 247.713 134.446 210.481 1.00 97.22  ? 328 GLU C OE2   1 
ATOM   5301 N N     . GLU B 2 326 ? 247.549 140.401 213.014 1.00 92.75  ? 329 GLU C N     1 
ATOM   5302 C CA    . GLU B 2 326 ? 247.683 141.730 213.601 1.00 92.75  ? 329 GLU C CA    1 
ATOM   5303 C C     . GLU B 2 326 ? 246.970 141.811 214.944 1.00 92.75  ? 329 GLU C C     1 
ATOM   5304 O O     . GLU B 2 326 ? 247.450 142.479 215.865 1.00 92.75  ? 329 GLU C O     1 
ATOM   5305 C CB    . GLU B 2 326 ? 247.154 142.791 212.639 1.00 92.75  ? 329 GLU C CB    1 
ATOM   5306 C CG    . GLU B 2 326 ? 247.888 142.853 211.309 1.00 92.75  ? 329 GLU C CG    1 
ATOM   5307 C CD    . GLU B 2 326 ? 249.235 143.548 211.395 1.00 92.75  ? 329 GLU C CD    1 
ATOM   5308 O OE1   . GLU B 2 326 ? 249.700 143.836 212.518 1.00 92.75  ? 329 GLU C OE1   1 
ATOM   5309 O OE2   . GLU B 2 326 ? 249.833 143.809 210.330 1.00 92.75  ? 329 GLU C OE2   1 
ATOM   5310 N N     . LEU B 2 327 ? 245.837 141.120 215.087 1.00 89.55  ? 330 LEU C N     1 
ATOM   5311 C CA    . LEU B 2 327 ? 245.146 141.100 216.372 1.00 89.55  ? 330 LEU C CA    1 
ATOM   5312 C C     . LEU B 2 327 ? 245.956 140.354 217.422 1.00 89.55  ? 330 LEU C C     1 
ATOM   5313 O O     . LEU B 2 327 ? 246.025 140.781 218.580 1.00 89.55  ? 330 LEU C O     1 
ATOM   5314 C CB    . LEU B 2 327 ? 243.765 140.469 216.222 1.00 89.55  ? 330 LEU C CB    1 
ATOM   5315 C CG    . LEU B 2 327 ? 243.073 140.063 217.524 1.00 89.55  ? 330 LEU C CG    1 
ATOM   5316 C CD1   . LEU B 2 327 ? 242.770 141.279 218.383 1.00 89.55  ? 330 LEU C CD1   1 
ATOM   5317 C CD2   . LEU B 2 327 ? 241.803 139.283 217.230 1.00 89.55  ? 330 LEU C CD2   1 
ATOM   5318 N N     . LEU B 2 328 ? 246.567 139.230 217.040 1.00 90.95  ? 331 LEU C N     1 
ATOM   5319 C CA    . LEU B 2 328 ? 247.448 138.531 217.972 1.00 90.95  ? 331 LEU C CA    1 
ATOM   5320 C C     . LEU B 2 328 ? 248.628 139.405 218.375 1.00 90.95  ? 331 LEU C C     1 
ATOM   5321 O O     . LEU B 2 328 ? 249.006 139.442 219.551 1.00 90.95  ? 331 LEU C O     1 
ATOM   5322 C CB    . LEU B 2 328 ? 247.941 137.217 217.368 1.00 90.95  ? 331 LEU C CB    1 
ATOM   5323 C CG    . LEU B 2 328 ? 247.119 135.965 217.674 1.00 90.95  ? 331 LEU C CG    1 
ATOM   5324 C CD1   . LEU B 2 328 ? 247.188 135.639 219.156 1.00 90.95  ? 331 LEU C CD1   1 
ATOM   5325 C CD2   . LEU B 2 328 ? 245.682 136.137 217.243 1.00 90.95  ? 331 LEU C CD2   1 
ATOM   5326 N N     . ALA B 2 329 ? 249.219 140.117 217.414 1.00 89.37  ? 332 ALA C N     1 
ATOM   5327 C CA    . ALA B 2 329 ? 250.335 141.001 217.730 1.00 89.37  ? 332 ALA C CA    1 
ATOM   5328 C C     . ALA B 2 329 ? 249.900 142.128 218.657 1.00 89.37  ? 332 ALA C C     1 
ATOM   5329 O O     . ALA B 2 329 ? 250.633 142.495 219.579 1.00 89.37  ? 332 ALA C O     1 
ATOM   5330 C CB    . ALA B 2 329 ? 250.940 141.564 216.445 1.00 89.37  ? 332 ALA C CB    1 
ATOM   5331 N N     . THR B 2 330 ? 248.703 142.677 218.442 1.00 86.78  ? 333 THR C N     1 
ATOM   5332 C CA    . THR B 2 330 ? 248.202 143.734 219.316 1.00 86.78  ? 333 THR C CA    1 
ATOM   5333 C C     . THR B 2 330 ? 247.953 143.216 220.726 1.00 86.78  ? 333 THR C C     1 
ATOM   5334 O O     . THR B 2 330 ? 248.323 143.869 221.709 1.00 86.78  ? 333 THR C O     1 
ATOM   5335 C CB    . THR B 2 330 ? 246.921 144.331 218.734 1.00 86.78  ? 333 THR C CB    1 
ATOM   5336 O OG1   . THR B 2 330 ? 247.205 144.933 217.466 1.00 86.78  ? 333 THR C OG1   1 
ATOM   5337 C CG2   . THR B 2 330 ? 246.344 145.376 219.669 1.00 86.78  ? 333 THR C CG2   1 
ATOM   5338 N N     . ASP B 2 331 ? 247.330 142.043 220.844 1.00 86.74  ? 334 ASP C N     1 
ATOM   5339 C CA    . ASP B 2 331 ? 247.075 141.469 222.160 1.00 86.74  ? 334 ASP C CA    1 
ATOM   5340 C C     . ASP B 2 331 ? 248.379 141.163 222.887 1.00 86.74  ? 334 ASP C C     1 
ATOM   5341 O O     . ASP B 2 331 ? 248.508 141.423 224.090 1.00 86.74  ? 334 ASP C O     1 
ATOM   5342 C CB    . ASP B 2 331 ? 246.227 140.208 222.015 1.00 86.74  ? 334 ASP C CB    1 
ATOM   5343 C CG    . ASP B 2 331 ? 245.441 139.890 223.265 1.00 86.74  ? 334 ASP C CG    1 
ATOM   5344 O OD1   . ASP B 2 331 ? 245.316 140.783 224.125 1.00 86.74  ? 334 ASP C OD1   1 
ATOM   5345 O OD2   . ASP B 2 331 ? 244.947 138.751 223.388 1.00 86.74  ? 334 ASP C OD2   1 
ATOM   5346 N N     . SER B 2 332 ? 249.370 140.631 222.168 1.00 87.30  ? 335 SER C N     1 
ATOM   5347 C CA    . SER B 2 332 ? 250.645 140.317 222.799 1.00 87.30  ? 335 SER C CA    1 
ATOM   5348 C C     . SER B 2 332 ? 251.428 141.575 223.144 1.00 87.30  ? 335 SER C C     1 
ATOM   5349 O O     . SER B 2 332 ? 252.182 141.578 224.119 1.00 87.30  ? 335 SER C O     1 
ATOM   5350 C CB    . SER B 2 332 ? 251.473 139.409 221.894 1.00 87.30  ? 335 SER C CB    1 
ATOM   5351 O OG    . SER B 2 332 ? 251.076 138.056 222.033 1.00 87.30  ? 335 SER C OG    1 
ATOM   5352 N N     . ALA B 2 333 ? 251.264 142.650 222.371 1.00 84.90  ? 336 ALA C N     1 
ATOM   5353 C CA    . ALA B 2 333 ? 251.898 143.912 222.730 1.00 84.90  ? 336 ALA C CA    1 
ATOM   5354 C C     . ALA B 2 333 ? 251.247 144.514 223.965 1.00 84.90  ? 336 ALA C C     1 
ATOM   5355 O O     . ALA B 2 333 ? 251.925 145.129 224.794 1.00 84.90  ? 336 ALA C O     1 
ATOM   5356 C CB    . ALA B 2 333 ? 251.833 144.889 221.558 1.00 84.90  ? 336 ALA C CB    1 
ATOM   5357 N N     . PHE B 2 334 ? 249.929 144.355 224.096 1.00 81.65  ? 337 PHE C N     1 
ATOM   5358 C CA    . PHE B 2 334 ? 249.258 144.755 225.327 1.00 81.65  ? 337 PHE C CA    1 
ATOM   5359 C C     . PHE B 2 334 ? 249.773 143.951 226.510 1.00 81.65  ? 337 PHE C C     1 
ATOM   5360 O O     . PHE B 2 334 ? 249.987 144.497 227.598 1.00 81.65  ? 337 PHE C O     1 
ATOM   5361 C CB    . PHE B 2 334 ? 247.748 144.581 225.187 1.00 81.65  ? 337 PHE C CB    1 
ATOM   5362 C CG    . PHE B 2 334 ? 247.063 145.738 224.529 1.00 81.65  ? 337 PHE C CG    1 
ATOM   5363 C CD1   . PHE B 2 334 ? 247.732 146.927 224.320 1.00 81.65  ? 337 PHE C CD1   1 
ATOM   5364 C CD2   . PHE B 2 334 ? 245.748 145.635 224.119 1.00 81.65  ? 337 PHE C CD2   1 
ATOM   5365 C CE1   . PHE B 2 334 ? 247.104 147.988 223.715 1.00 81.65  ? 337 PHE C CE1   1 
ATOM   5366 C CE2   . PHE B 2 334 ? 245.116 146.696 223.513 1.00 81.65  ? 337 PHE C CE2   1 
ATOM   5367 C CZ    . PHE B 2 334 ? 245.795 147.873 223.311 1.00 81.65  ? 337 PHE C CZ    1 
ATOM   5368 N N     . ASP B 2 335 ? 249.978 142.648 226.316 1.00 86.74  ? 338 ASP C N     1 
ATOM   5369 C CA    . ASP B 2 335 ? 250.486 141.817 227.403 1.00 86.74  ? 338 ASP C CA    1 
ATOM   5370 C C     . ASP B 2 335 ? 251.928 142.172 227.751 1.00 86.74  ? 338 ASP C C     1 
ATOM   5371 O O     . ASP B 2 335 ? 252.326 142.090 228.918 1.00 86.74  ? 338 ASP C O     1 
ATOM   5372 C CB    . ASP B 2 335 ? 250.366 140.341 227.034 1.00 86.74  ? 338 ASP C CB    1 
ATOM   5373 C CG    . ASP B 2 335 ? 250.323 139.442 228.251 1.00 86.74  ? 338 ASP C CG    1 
ATOM   5374 O OD1   . ASP B 2 335 ? 249.872 139.909 229.318 1.00 86.74  ? 338 ASP C OD1   1 
ATOM   5375 O OD2   . ASP B 2 335 ? 250.739 138.269 228.143 1.00 86.74  ? 338 ASP C OD2   1 
ATOM   5376 N N     . VAL B 2 336 ? 252.727 142.562 226.755 1.00 85.46  ? 339 VAL C N     1 
ATOM   5377 C CA    . VAL B 2 336 ? 254.093 143.005 227.023 1.00 85.46  ? 339 VAL C CA    1 
ATOM   5378 C C     . VAL B 2 336 ? 254.085 144.234 227.917 1.00 85.46  ? 339 VAL C C     1 
ATOM   5379 O O     . VAL B 2 336 ? 254.864 144.332 228.871 1.00 85.46  ? 339 VAL C O     1 
ATOM   5380 C CB    . VAL B 2 336 ? 254.846 143.271 225.707 1.00 85.46  ? 339 VAL C CB    1 
ATOM   5381 C CG1   . VAL B 2 336 ? 256.144 144.007 225.983 1.00 85.46  ? 339 VAL C CG1   1 
ATOM   5382 C CG2   . VAL B 2 336 ? 255.143 141.963 224.995 1.00 85.46  ? 339 VAL C CG2   1 
ATOM   5383 N N     . LEU B 2 337 ? 253.205 145.186 227.630 1.00 84.42  ? 340 LEU C N     1 
ATOM   5384 C CA    . LEU B 2 337 ? 253.068 146.342 228.494 1.00 84.42  ? 340 LEU C CA    1 
ATOM   5385 C C     . LEU B 2 337 ? 252.535 145.907 229.858 1.00 84.42  ? 340 LEU C C     1 
ATOM   5386 O O     . LEU B 2 337 ? 252.191 144.744 230.084 1.00 84.42  ? 340 LEU C O     1 
ATOM   5387 C CB    . LEU B 2 337 ? 252.138 147.376 227.863 1.00 84.42  ? 340 LEU C CB    1 
ATOM   5388 C CG    . LEU B 2 337 ? 252.547 147.906 226.488 1.00 84.42  ? 340 LEU C CG    1 
ATOM   5389 C CD1   . LEU B 2 337 ? 251.506 148.874 225.959 1.00 84.42  ? 340 LEU C CD1   1 
ATOM   5390 C CD2   . LEU B 2 337 ? 253.918 148.548 226.517 1.00 84.42  ? 340 LEU C CD2   1 
ATOM   5391 N N     . SER B 2 338 ? 252.452 146.863 230.776 1.00 84.34  ? 341 SER C N     1 
ATOM   5392 C CA    . SER B 2 338 ? 251.971 146.577 232.121 1.00 84.34  ? 341 SER C CA    1 
ATOM   5393 C C     . SER B 2 338 ? 250.461 146.378 232.180 1.00 84.34  ? 341 SER C C     1 
ATOM   5394 O O     . SER B 2 338 ? 249.898 146.354 233.279 1.00 84.34  ? 341 SER C O     1 
ATOM   5395 C CB    . SER B 2 338 ? 252.389 147.698 233.076 1.00 84.34  ? 341 SER C CB    1 
ATOM   5396 O OG    . SER B 2 338 ? 253.795 147.878 233.061 1.00 84.34  ? 341 SER C OG    1 
ATOM   5397 N N     . PHE B 2 339 ? 249.804 146.246 231.029 1.00 82.10  ? 342 PHE C N     1 
ATOM   5398 C CA    . PHE B 2 339 ? 248.357 146.087 230.987 1.00 82.10  ? 342 PHE C CA    1 
ATOM   5399 C C     . PHE B 2 339 ? 247.925 144.857 231.770 1.00 82.10  ? 342 PHE C C     1 
ATOM   5400 O O     . PHE B 2 339 ? 248.469 143.765 231.586 1.00 82.10  ? 342 PHE C O     1 
ATOM   5401 C CB    . PHE B 2 339 ? 247.881 145.973 229.540 1.00 82.10  ? 342 PHE C CB    1 
ATOM   5402 C CG    . PHE B 2 339 ? 247.753 147.289 228.834 1.00 82.10  ? 342 PHE C CG    1 
ATOM   5403 C CD1   . PHE B 2 339 ? 248.778 148.215 228.871 1.00 82.10  ? 342 PHE C CD1   1 
ATOM   5404 C CD2   . PHE B 2 339 ? 246.607 147.599 228.131 1.00 82.10  ? 342 PHE C CD2   1 
ATOM   5405 C CE1   . PHE B 2 339 ? 248.660 149.424 228.220 1.00 82.10  ? 342 PHE C CE1   1 
ATOM   5406 C CE2   . PHE B 2 339 ? 246.485 148.805 227.478 1.00 82.10  ? 342 PHE C CE2   1 
ATOM   5407 C CZ    . PHE B 2 339 ? 247.512 149.719 227.523 1.00 82.10  ? 342 PHE C CZ    1 
ATOM   5408 N N     . THR B 2 340 ? 246.943 145.038 232.644 1.00 83.64  ? 343 THR C N     1 
ATOM   5409 C CA    . THR B 2 340 ? 246.375 143.950 233.417 1.00 83.64  ? 343 THR C CA    1 
ATOM   5410 C C     . THR B 2 340 ? 245.130 143.419 232.713 1.00 83.64  ? 343 THR C C     1 
ATOM   5411 O O     . THR B 2 340 ? 244.684 143.953 231.696 1.00 83.64  ? 343 THR C O     1 
ATOM   5412 C CB    . THR B 2 340 ? 246.058 144.413 234.838 1.00 83.64  ? 343 THR C CB    1 
ATOM   5413 O OG1   . THR B 2 340 ? 244.911 145.269 234.814 1.00 83.64  ? 343 THR C OG1   1 
ATOM   5414 C CG2   . THR B 2 340 ? 247.234 145.175 235.416 1.00 83.64  ? 343 THR C CG2   1 
ATOM   5415 N N     . ALA B 2 341 ? 244.563 142.345 233.267 1.00 83.36  ? 344 ALA C N     1 
ATOM   5416 C CA    . ALA B 2 341 ? 243.435 141.688 232.616 1.00 83.36  ? 344 ALA C CA    1 
ATOM   5417 C C     . ALA B 2 341 ? 242.232 142.613 232.486 1.00 83.36  ? 344 ALA C C     1 
ATOM   5418 O O     . ALA B 2 341 ? 241.508 142.543 231.487 1.00 83.36  ? 344 ALA C O     1 
ATOM   5419 C CB    . ALA B 2 341 ? 243.049 140.424 233.382 1.00 83.36  ? 344 ALA C CB    1 
ATOM   5420 N N     . GLU B 2 342 ? 242.005 143.485 233.469 1.00 84.45  ? 345 GLU C N     1 
ATOM   5421 C CA    . GLU B 2 342 ? 240.866 144.392 233.390 1.00 84.45  ? 345 GLU C CA    1 
ATOM   5422 C C     . GLU B 2 342 ? 241.144 145.569 232.461 1.00 84.45  ? 345 GLU C C     1 
ATOM   5423 O O     . GLU B 2 342 ? 240.226 146.063 231.797 1.00 84.45  ? 345 GLU C O     1 
ATOM   5424 C CB    . GLU B 2 342 ? 240.477 144.882 234.787 1.00 84.45  ? 345 GLU C CB    1 
ATOM   5425 C CG    . GLU B 2 342 ? 241.356 145.984 235.360 1.00 84.45  ? 345 GLU C CG    1 
ATOM   5426 C CD    . GLU B 2 342 ? 242.359 145.467 236.372 1.00 84.45  ? 345 GLU C CD    1 
ATOM   5427 O OE1   . GLU B 2 342 ? 243.047 144.469 236.075 1.00 84.45  ? 345 GLU C OE1   1 
ATOM   5428 O OE2   . GLU B 2 342 ? 242.459 146.059 237.467 1.00 84.45  ? 345 GLU C OE2   1 
ATOM   5429 N N     . GLU B 2 343 ? 242.397 146.026 232.387 1.00 82.50  ? 346 GLU C N     1 
ATOM   5430 C CA    . GLU B 2 343 ? 242.718 147.177 231.541 1.00 82.50  ? 346 GLU C CA    1 
ATOM   5431 C C     . GLU B 2 343 ? 242.852 146.817 230.075 1.00 82.50  ? 346 GLU C C     1 
ATOM   5432 O O     . GLU B 2 343 ? 243.181 147.686 229.262 1.00 82.50  ? 346 GLU C O     1 
ATOM   5433 C CB    . GLU B 2 343 ? 243.999 147.848 232.035 1.00 82.50  ? 346 GLU C CB    1 
ATOM   5434 C CG    . GLU B 2 343 ? 243.868 148.482 233.407 1.00 82.50  ? 346 GLU C CG    1 
ATOM   5435 C CD    . GLU B 2 343 ? 245.203 148.642 234.104 1.00 82.50  ? 346 GLU C CD    1 
ATOM   5436 O OE1   . GLU B 2 343 ? 246.050 149.407 233.599 1.00 82.50  ? 346 GLU C OE1   1 
ATOM   5437 O OE2   . GLU B 2 343 ? 245.407 148.001 235.156 1.00 82.50  ? 346 GLU C OE2   1 
ATOM   5438 N N     . LYS B 2 344 ? 242.609 145.561 229.720 1.00 79.67  ? 347 LYS C N     1 
ATOM   5439 C CA    . LYS B 2 344 ? 242.512 145.130 228.333 1.00 79.67  ? 347 LYS C CA    1 
ATOM   5440 C C     . LYS B 2 344 ? 241.066 144.918 227.924 1.00 79.67  ? 347 LYS C C     1 
ATOM   5441 O O     . LYS B 2 344 ? 240.648 145.365 226.844 1.00 79.67  ? 347 LYS C O     1 
ATOM   5442 C CB    . LYS B 2 344 ? 243.307 143.833 228.136 1.00 79.67  ? 347 LYS C CB    1 
ATOM   5443 C CG    . LYS B 2 344 ? 244.804 143.995 228.249 1.00 79.67  ? 347 LYS C CG    1 
ATOM   5444 C CD    . LYS B 2 344 ? 245.471 142.641 228.353 1.00 79.67  ? 347 LYS C CD    1 
ATOM   5445 C CE    . LYS B 2 344 ? 245.338 141.863 227.068 1.00 79.67  ? 347 LYS C CE    1 
ATOM   5446 N NZ    . LYS B 2 344 ? 246.073 140.572 227.139 1.00 79.67  ? 347 LYS C NZ    1 
ATOM   5447 N N     . ALA B 2 345 ? 240.291 144.237 228.770 1.00 76.02  ? 348 ALA C N     1 
ATOM   5448 C CA    . ALA B 2 345 ? 238.852 144.178 228.571 1.00 76.02  ? 348 ALA C CA    1 
ATOM   5449 C C     . ALA B 2 345 ? 238.249 145.570 228.543 1.00 76.02  ? 348 ALA C C     1 
ATOM   5450 O O     . ALA B 2 345 ? 237.282 145.805 227.818 1.00 76.02  ? 348 ALA C O     1 
ATOM   5451 C CB    . ALA B 2 345 ? 238.203 143.336 229.667 1.00 76.02  ? 348 ALA C CB    1 
ATOM   5452 N N     . GLY B 2 346 ? 238.815 146.512 229.299 1.00 73.80  ? 349 GLY C N     1 
ATOM   5453 C CA    . GLY B 2 346 ? 238.329 147.880 229.236 1.00 73.80  ? 349 GLY C CA    1 
ATOM   5454 C C     . GLY B 2 346 ? 238.474 148.488 227.854 1.00 73.80  ? 349 GLY C C     1 
ATOM   5455 O O     . GLY B 2 346 ? 237.520 149.044 227.308 1.00 73.80  ? 349 GLY C O     1 
ATOM   5456 N N     . VAL B 2 347 ? 239.669 148.384 227.270 1.00 71.46  ? 350 VAL C N     1 
ATOM   5457 C CA    . VAL B 2 347 ? 239.905 148.928 225.935 1.00 71.46  ? 350 VAL C CA    1 
ATOM   5458 C C     . VAL B 2 347 ? 239.014 148.240 224.908 1.00 71.46  ? 350 VAL C C     1 
ATOM   5459 O O     . VAL B 2 347 ? 238.417 148.893 224.038 1.00 71.46  ? 350 VAL C O     1 
ATOM   5460 C CB    . VAL B 2 347 ? 241.393 148.794 225.570 1.00 71.46  ? 350 VAL C CB    1 
ATOM   5461 C CG1   . VAL B 2 347 ? 241.621 149.210 224.145 1.00 71.46  ? 350 VAL C CG1   1 
ATOM   5462 C CG2   . VAL B 2 347 ? 242.236 149.631 226.501 1.00 71.46  ? 350 VAL C CG2   1 
ATOM   5463 N N     . TYR B 2 348 ? 238.913 146.912 224.988 1.00 74.73  ? 351 TYR C N     1 
ATOM   5464 C CA    . TYR B 2 348 ? 238.084 146.185 224.033 1.00 74.73  ? 351 TYR C CA    1 
ATOM   5465 C C     . TYR B 2 348 ? 236.617 146.577 224.161 1.00 74.73  ? 351 TYR C C     1 
ATOM   5466 O O     . TYR B 2 348 ? 235.920 146.746 223.153 1.00 74.73  ? 351 TYR C O     1 
ATOM   5467 C CB    . TYR B 2 348 ? 238.269 144.684 224.227 1.00 74.73  ? 351 TYR C CB    1 
ATOM   5468 C CG    . TYR B 2 348 ? 239.633 144.196 223.804 1.00 74.73  ? 351 TYR C CG    1 
ATOM   5469 C CD1   . TYR B 2 348 ? 240.256 144.717 222.682 1.00 74.73  ? 351 TYR C CD1   1 
ATOM   5470 C CD2   . TYR B 2 348 ? 240.304 143.232 224.537 1.00 74.73  ? 351 TYR C CD2   1 
ATOM   5471 C CE1   . TYR B 2 348 ? 241.503 144.279 222.292 1.00 74.73  ? 351 TYR C CE1   1 
ATOM   5472 C CE2   . TYR B 2 348 ? 241.549 142.787 224.154 1.00 74.73  ? 351 TYR C CE2   1 
ATOM   5473 C CZ    . TYR B 2 348 ? 242.144 143.315 223.033 1.00 74.73  ? 351 TYR C CZ    1 
ATOM   5474 O OH    . TYR B 2 348 ? 243.387 142.874 222.653 1.00 74.73  ? 351 TYR C OH    1 
ATOM   5475 N N     . LYS B 2 349 ? 236.134 146.745 225.392 1.00 70.33  ? 352 LYS C N     1 
ATOM   5476 C CA    . LYS B 2 349 ? 234.752 147.151 225.603 1.00 70.33  ? 352 LYS C CA    1 
ATOM   5477 C C     . LYS B 2 349 ? 234.508 148.562 225.094 1.00 70.33  ? 352 LYS C C     1 
ATOM   5478 O O     . LYS B 2 349 ? 233.435 148.853 224.560 1.00 70.33  ? 352 LYS C O     1 
ATOM   5479 C CB    . LYS B 2 349 ? 234.399 147.055 227.084 1.00 70.33  ? 352 LYS C CB    1 
ATOM   5480 C CG    . LYS B 2 349 ? 234.169 145.648 227.592 1.00 70.33  ? 352 LYS C CG    1 
ATOM   5481 C CD    . LYS B 2 349 ? 234.032 145.659 229.101 1.00 70.33  ? 352 LYS C CD    1 
ATOM   5482 C CE    . LYS B 2 349 ? 233.985 144.258 229.670 1.00 70.33  ? 352 LYS C CE    1 
ATOM   5483 N NZ    . LYS B 2 349 ? 233.850 144.288 231.152 1.00 70.33  ? 352 LYS C NZ    1 
ATOM   5484 N N     . LEU B 2 350 ? 235.479 149.458 225.262 1.00 67.87  ? 353 LEU C N     1 
ATOM   5485 C CA    . LEU B 2 350 ? 235.296 150.815 224.759 1.00 67.87  ? 353 LEU C CA    1 
ATOM   5486 C C     . LEU B 2 350 ? 235.240 150.831 223.238 1.00 67.87  ? 353 LEU C C     1 
ATOM   5487 O O     . LEU B 2 350 ? 234.450 151.577 222.646 1.00 67.87  ? 353 LEU C O     1 
ATOM   5488 C CB    . LEU B 2 350 ? 236.409 151.725 225.267 1.00 67.87  ? 353 LEU C CB    1 
ATOM   5489 C CG    . LEU B 2 350 ? 236.403 151.949 226.777 1.00 67.87  ? 353 LEU C CG    1 
ATOM   5490 C CD1   . LEU B 2 350 ? 237.474 152.940 227.165 1.00 67.87  ? 353 LEU C CD1   1 
ATOM   5491 C CD2   . LEU B 2 350 ? 235.040 152.401 227.257 1.00 67.87  ? 353 LEU C CD2   1 
ATOM   5492 N N     . THR B 2 351 ? 236.052 150.000 222.587 1.00 67.46  ? 354 THR C N     1 
ATOM   5493 C CA    . THR B 2 351 ? 235.972 149.920 221.132 1.00 67.46  ? 354 THR C CA    1 
ATOM   5494 C C     . THR B 2 351 ? 234.642 149.319 220.689 1.00 67.46  ? 354 THR C C     1 
ATOM   5495 O O     . THR B 2 351 ? 234.033 149.786 219.718 1.00 67.46  ? 354 THR C O     1 
ATOM   5496 C CB    . THR B 2 351 ? 237.149 149.117 220.583 1.00 67.46  ? 354 THR C CB    1 
ATOM   5497 O OG1   . THR B 2 351 ? 238.357 149.861 220.776 1.00 67.46  ? 354 THR C OG1   1 
ATOM   5498 C CG2   . THR B 2 351 ? 236.973 148.857 219.101 1.00 67.46  ? 354 THR C CG2   1 
ATOM   5499 N N     . GLY B 2 352 ? 234.156 148.303 221.402 1.00 69.03  ? 355 GLY C N     1 
ATOM   5500 C CA    . GLY B 2 352 ? 232.846 147.756 221.082 1.00 69.03  ? 355 GLY C CA    1 
ATOM   5501 C C     . GLY B 2 352 ? 231.728 148.762 221.285 1.00 69.03  ? 355 GLY C C     1 
ATOM   5502 O O     . GLY B 2 352 ? 230.752 148.786 220.531 1.00 69.03  ? 355 GLY C O     1 
ATOM   5503 N N     . ALA B 2 353 ? 231.862 149.618 222.297 1.00 68.30  ? 356 ALA C N     1 
ATOM   5504 C CA    . ALA B 2 353 ? 230.861 150.651 222.532 1.00 68.30  ? 356 ALA C CA    1 
ATOM   5505 C C     . ALA B 2 353 ? 230.891 151.708 221.438 1.00 68.30  ? 356 ALA C C     1 
ATOM   5506 O O     . ALA B 2 353 ? 229.842 152.213 221.024 1.00 68.30  ? 356 ALA C O     1 
ATOM   5507 C CB    . ALA B 2 353 ? 231.082 151.290 223.900 1.00 68.30  ? 356 ALA C CB    1 
ATOM   5508 N N     . ILE B 2 354 ? 232.085 152.062 220.960 1.00 67.06  ? 357 ILE C N     1 
ATOM   5509 C CA    . ILE B 2 354 ? 232.163 152.976 219.825 1.00 67.06  ? 357 ILE C CA    1 
ATOM   5510 C C     . ILE B 2 354 ? 231.578 152.325 218.579 1.00 67.06  ? 357 ILE C C     1 
ATOM   5511 O O     . ILE B 2 354 ? 231.023 153.010 217.713 1.00 67.06  ? 357 ILE C O     1 
ATOM   5512 C CB    . ILE B 2 354 ? 233.613 153.436 219.602 1.00 67.06  ? 357 ILE C CB    1 
ATOM   5513 C CG1   . ILE B 2 354 ? 234.124 154.162 220.840 1.00 67.06  ? 357 ILE C CG1   1 
ATOM   5514 C CG2   . ILE B 2 354 ? 233.711 154.356 218.399 1.00 67.06  ? 357 ILE C CG2   1 
ATOM   5515 C CD1   . ILE B 2 354 ? 235.509 154.717 220.679 1.00 67.06  ? 357 ILE C CD1   1 
ATOM   5516 N N     . MET B 2 355 ? 231.671 151.001 218.470 1.00 70.17  ? 358 MET C N     1 
ATOM   5517 C CA    . MET B 2 355 ? 231.032 150.322 217.347 1.00 70.17  ? 358 MET C CA    1 
ATOM   5518 C C     . MET B 2 355 ? 229.514 150.371 217.462 1.00 70.17  ? 358 MET C C     1 
ATOM   5519 O O     . MET B 2 355 ? 228.817 150.562 216.460 1.00 70.17  ? 358 MET C O     1 
ATOM   5520 C CB    . MET B 2 355 ? 231.515 148.876 217.258 1.00 70.17  ? 358 MET C CB    1 
ATOM   5521 C CG    . MET B 2 355 ? 232.693 148.679 216.328 1.00 70.17  ? 358 MET C CG    1 
ATOM   5522 S SD    . MET B 2 355 ? 233.026 146.947 215.972 1.00 70.17  ? 358 MET C SD    1 
ATOM   5523 C CE    . MET B 2 355 ? 233.353 146.331 217.615 1.00 70.17  ? 358 MET C CE    1 
ATOM   5524 N N     . HIS B 2 356 ? 228.983 150.194 218.675 1.00 70.14  ? 359 HIS C N     1 
ATOM   5525 C CA    . HIS B 2 356 ? 227.537 150.215 218.887 1.00 70.14  ? 359 HIS C CA    1 
ATOM   5526 C C     . HIS B 2 356 ? 226.941 151.616 218.862 1.00 70.14  ? 359 HIS C C     1 
ATOM   5527 O O     . HIS B 2 356 ? 225.727 151.748 218.696 1.00 70.14  ? 359 HIS C O     1 
ATOM   5528 C CB    . HIS B 2 356 ? 227.175 149.551 220.215 1.00 70.14  ? 359 HIS C CB    1 
ATOM   5529 C CG    . HIS B 2 356 ? 227.293 148.061 220.204 1.00 70.14  ? 359 HIS C CG    1 
ATOM   5530 N ND1   . HIS B 2 356 ? 226.377 147.248 219.576 1.00 70.14  ? 359 HIS C ND1   1 
ATOM   5531 C CD2   . HIS B 2 356 ? 228.205 147.235 220.766 1.00 70.14  ? 359 HIS C CD2   1 
ATOM   5532 C CE1   . HIS B 2 356 ? 226.727 145.985 219.739 1.00 70.14  ? 359 HIS C CE1   1 
ATOM   5533 N NE2   . HIS B 2 356 ? 227.834 145.950 220.457 1.00 70.14  ? 359 HIS C NE2   1 
ATOM   5534 N N     . TYR B 2 357 ? 227.753 152.656 219.055 1.00 70.88  ? 360 TYR C N     1 
ATOM   5535 C CA    . TYR B 2 357 ? 227.247 154.017 218.899 1.00 70.88  ? 360 TYR C CA    1 
ATOM   5536 C C     . TYR B 2 357 ? 226.676 154.243 217.506 1.00 70.88  ? 360 TYR C C     1 
ATOM   5537 O O     . TYR B 2 357 ? 225.614 154.855 217.353 1.00 70.88  ? 360 TYR C O     1 
ATOM   5538 C CB    . TYR B 2 357 ? 228.356 155.033 219.149 1.00 70.88  ? 360 TYR C CB    1 
ATOM   5539 C CG    . TYR B 2 357 ? 228.769 155.243 220.584 1.00 70.88  ? 360 TYR C CG    1 
ATOM   5540 C CD1   . TYR B 2 357 ? 227.966 154.853 221.643 1.00 70.88  ? 360 TYR C CD1   1 
ATOM   5541 C CD2   . TYR B 2 357 ? 229.982 155.850 220.871 1.00 70.88  ? 360 TYR C CD2   1 
ATOM   5542 C CE1   . TYR B 2 357 ? 228.371 155.066 222.954 1.00 70.88  ? 360 TYR C CE1   1 
ATOM   5543 C CE2   . TYR B 2 357 ? 230.393 156.063 222.159 1.00 70.88  ? 360 TYR C CE2   1 
ATOM   5544 C CZ    . TYR B 2 357 ? 229.591 155.672 223.198 1.00 70.88  ? 360 TYR C CZ    1 
ATOM   5545 O OH    . TYR B 2 357 ? 230.030 155.902 224.481 1.00 70.88  ? 360 TYR C OH    1 
ATOM   5546 N N     . GLY B 2 358 ? 227.367 153.753 216.478 1.00 73.49  ? 361 GLY C N     1 
ATOM   5547 C CA    . GLY B 2 358 ? 227.056 154.165 215.121 1.00 73.49  ? 361 GLY C CA    1 
ATOM   5548 C C     . GLY B 2 358 ? 225.677 153.757 214.649 1.00 73.49  ? 361 GLY C C     1 
ATOM   5549 O O     . GLY B 2 358 ? 225.114 154.391 213.753 1.00 73.49  ? 361 GLY C O     1 
ATOM   5550 N N     . ASN B 2 359 ? 225.110 152.706 215.231 1.00 75.15  ? 362 ASN C N     1 
ATOM   5551 C CA    . ASN B 2 359 ? 223.814 152.194 214.800 1.00 75.15  ? 362 ASN C CA    1 
ATOM   5552 C C     . ASN B 2 359 ? 222.746 152.368 215.876 1.00 75.15  ? 362 ASN C C     1 
ATOM   5553 O O     . ASN B 2 359 ? 221.921 151.484 216.107 1.00 75.15  ? 362 ASN C O     1 
ATOM   5554 C CB    . ASN B 2 359 ? 223.920 150.735 214.364 1.00 75.15  ? 362 ASN C CB    1 
ATOM   5555 C CG    . ASN B 2 359 ? 224.521 149.852 215.423 1.00 75.15  ? 362 ASN C CG    1 
ATOM   5556 O OD1   . ASN B 2 359 ? 224.637 150.249 216.576 1.00 75.15  ? 362 ASN C OD1   1 
ATOM   5557 N ND2   . ASN B 2 359 ? 224.913 148.645 215.038 1.00 75.15  ? 362 ASN C ND2   1 
ATOM   5558 N N     . MET B 2 360 ? 222.756 153.514 216.550 1.00 77.25  ? 363 MET C N     1 
ATOM   5559 C CA    . MET B 2 360 ? 221.610 153.954 217.328 1.00 77.25  ? 363 MET C CA    1 
ATOM   5560 C C     . MET B 2 360 ? 220.728 154.819 216.442 1.00 77.25  ? 363 MET C C     1 
ATOM   5561 O O     . MET B 2 360 ? 221.224 155.595 215.621 1.00 77.25  ? 363 MET C O     1 
ATOM   5562 C CB    . MET B 2 360 ? 222.042 154.740 218.566 1.00 77.25  ? 363 MET C CB    1 
ATOM   5563 C CG    . MET B 2 360 ? 223.164 154.106 219.361 1.00 77.25  ? 363 MET C CG    1 
ATOM   5564 S SD    . MET B 2 360 ? 223.693 155.141 220.738 1.00 77.25  ? 363 MET C SD    1 
ATOM   5565 C CE    . MET B 2 360 ? 222.304 154.959 221.844 1.00 77.25  ? 363 MET C CE    1 
ATOM   5566 N N     . LYS B 2 361 ? 219.417 154.682 216.608 1.00 79.37  ? 364 LYS C N     1 
ATOM   5567 C CA    . LYS B 2 361 ? 218.461 155.336 215.728 1.00 79.37  ? 364 LYS C CA    1 
ATOM   5568 C C     . LYS B 2 361 ? 217.496 156.171 216.553 1.00 79.37  ? 364 LYS C C     1 
ATOM   5569 O O     . LYS B 2 361 ? 216.984 155.705 217.575 1.00 79.37  ? 364 LYS C O     1 
ATOM   5570 C CB    . LYS B 2 361 ? 217.695 154.309 214.893 1.00 79.37  ? 364 LYS C CB    1 
ATOM   5571 C CG    . LYS B 2 361 ? 218.591 153.362 214.121 1.00 79.37  ? 364 LYS C CG    1 
ATOM   5572 C CD    . LYS B 2 361 ? 217.826 152.149 213.641 1.00 79.37  ? 364 LYS C CD    1 
ATOM   5573 C CE    . LYS B 2 361 ? 218.733 151.199 212.881 1.00 79.37  ? 364 LYS C CE    1 
ATOM   5574 N NZ    . LYS B 2 361 ? 219.790 150.623 213.755 1.00 79.37  ? 364 LYS C NZ    1 
ATOM   5575 N N     . PHE B 2 362 ? 217.252 157.397 216.102 1.00 76.53  ? 365 PHE C N     1 
ATOM   5576 C CA    . PHE B 2 362 ? 216.328 158.312 216.750 1.00 76.53  ? 365 PHE C CA    1 
ATOM   5577 C C     . PHE B 2 362 ? 215.320 158.814 215.728 1.00 76.53  ? 365 PHE C C     1 
ATOM   5578 O O     . PHE B 2 362 ? 215.615 158.902 214.534 1.00 76.53  ? 365 PHE C O     1 
ATOM   5579 C CB    . PHE B 2 362 ? 217.061 159.495 217.384 1.00 76.53  ? 365 PHE C CB    1 
ATOM   5580 C CG    . PHE B 2 362 ? 217.924 159.118 218.552 1.00 76.53  ? 365 PHE C CG    1 
ATOM   5581 C CD1   . PHE B 2 362 ? 217.504 159.361 219.845 1.00 76.53  ? 365 PHE C CD1   1 
ATOM   5582 C CD2   . PHE B 2 362 ? 219.156 158.527 218.358 1.00 76.53  ? 365 PHE C CD2   1 
ATOM   5583 C CE1   . PHE B 2 362 ? 218.292 159.017 220.917 1.00 76.53  ? 365 PHE C CE1   1 
ATOM   5584 C CE2   . PHE B 2 362 ? 219.945 158.182 219.429 1.00 76.53  ? 365 PHE C CE2   1 
ATOM   5585 C CZ    . PHE B 2 362 ? 219.513 158.427 220.709 1.00 76.53  ? 365 PHE C CZ    1 
ATOM   5586 N N     . LYS B 2 363 ? 214.127 159.146 216.206 1.00 82.59  ? 366 LYS C N     1 
ATOM   5587 C CA    . LYS B 2 363 ? 213.044 159.585 215.342 1.00 82.59  ? 366 LYS C CA    1 
ATOM   5588 C C     . LYS B 2 363 ? 212.480 160.904 215.848 1.00 82.59  ? 366 LYS C C     1 
ATOM   5589 O O     . LYS B 2 363 ? 212.545 161.210 217.040 1.00 82.59  ? 366 LYS C O     1 
ATOM   5590 C CB    . LYS B 2 363 ? 211.932 158.536 215.269 1.00 82.59  ? 366 LYS C CB    1 
ATOM   5591 C CG    . LYS B 2 363 ? 211.298 158.220 216.606 1.00 82.59  ? 366 LYS C CG    1 
ATOM   5592 C CD    . LYS B 2 363 ? 210.257 157.129 216.473 1.00 82.59  ? 366 LYS C CD    1 
ATOM   5593 C CE    . LYS B 2 363 ? 209.721 156.713 217.830 1.00 82.59  ? 366 LYS C CE    1 
ATOM   5594 N NZ    . LYS B 2 363 ? 208.821 155.532 217.727 1.00 82.59  ? 366 LYS C NZ    1 
ATOM   5595 N N     . GLN B 2 364 ? 211.935 161.687 214.922 1.00 84.45  ? 367 GLN C N     1 
ATOM   5596 C CA    . GLN B 2 364 ? 211.271 162.926 215.295 1.00 84.45  ? 367 GLN C CA    1 
ATOM   5597 C C     . GLN B 2 364 ? 210.002 162.612 216.073 1.00 84.45  ? 367 GLN C C     1 
ATOM   5598 O O     . GLN B 2 364 ? 209.237 161.721 215.694 1.00 84.45  ? 367 GLN C O     1 
ATOM   5599 C CB    . GLN B 2 364 ? 210.939 163.748 214.051 1.00 84.45  ? 367 GLN C CB    1 
ATOM   5600 C CG    . GLN B 2 364 ? 212.154 164.254 213.289 1.00 84.45  ? 367 GLN C CG    1 
ATOM   5601 C CD    . GLN B 2 364 ? 212.901 165.350 214.026 1.00 84.45  ? 367 GLN C CD    1 
ATOM   5602 O OE1   . GLN B 2 364 ? 212.397 165.919 214.994 1.00 84.45  ? 367 GLN C OE1   1 
ATOM   5603 N NE2   . GLN B 2 364 ? 214.108 165.654 213.567 1.00 84.45  ? 367 GLN C NE2   1 
ATOM   5604 N N     . LYS B 2 365 ? 209.784 163.335 217.168 1.00 88.80  ? 368 LYS C N     1 
ATOM   5605 C CA    . LYS B 2 365 ? 208.588 163.120 217.968 1.00 88.80  ? 368 LYS C CA    1 
ATOM   5606 C C     . LYS B 2 365 ? 207.340 163.416 217.147 1.00 88.80  ? 368 LYS C C     1 
ATOM   5607 O O     . LYS B 2 365 ? 207.350 164.250 216.239 1.00 88.80  ? 368 LYS C O     1 
ATOM   5608 C CB    . LYS B 2 365 ? 208.616 163.995 219.220 1.00 88.80  ? 368 LYS C CB    1 
ATOM   5609 C CG    . LYS B 2 365 ? 208.473 163.214 220.512 1.00 88.80  ? 368 LYS C CG    1 
ATOM   5610 C CD    . LYS B 2 365 ? 208.908 164.040 221.705 1.00 88.80  ? 368 LYS C CD    1 
ATOM   5611 C CE    . LYS B 2 365 ? 209.033 163.186 222.950 1.00 88.80  ? 368 LYS C CE    1 
ATOM   5612 N NZ    . LYS B 2 365 ? 209.516 163.981 224.110 1.00 88.80  ? 368 LYS C NZ    1 
ATOM   5613 N N     . GLN B 2 366 ? 206.260 162.711 217.472 1.00 96.73  ? 369 GLN C N     1 
ATOM   5614 C CA    . GLN B 2 366 ? 205.019 162.840 216.720 1.00 96.73  ? 369 GLN C CA    1 
ATOM   5615 C C     . GLN B 2 366 ? 204.472 164.256 216.832 1.00 96.73  ? 369 GLN C C     1 
ATOM   5616 O O     . GLN B 2 366 ? 204.164 164.726 217.932 1.00 96.73  ? 369 GLN C O     1 
ATOM   5617 C CB    . GLN B 2 366 ? 203.993 161.826 217.222 1.00 96.73  ? 369 GLN C CB    1 
ATOM   5618 C CG    . GLN B 2 366 ? 204.461 160.376 217.174 1.00 96.73  ? 369 GLN C CG    1 
ATOM   5619 C CD    . GLN B 2 366 ? 205.132 160.009 215.862 1.00 96.73  ? 369 GLN C CD    1 
ATOM   5620 O OE1   . GLN B 2 366 ? 204.471 159.605 214.907 1.00 96.73  ? 369 GLN C OE1   1 
ATOM   5621 N NE2   . GLN B 2 366 ? 206.455 160.125 215.819 1.00 96.73  ? 369 GLN C NE2   1 
ATOM   5622 N N     . ARG B 2 367 ? 204.381 164.937 215.689 1.00 96.91  ? 370 ARG C N     1 
ATOM   5623 C CA    . ARG B 2 367 ? 203.875 166.297 215.523 1.00 96.91  ? 370 ARG C CA    1 
ATOM   5624 C C     . ARG B 2 367 ? 204.835 167.353 216.056 1.00 96.91  ? 370 ARG C C     1 
ATOM   5625 O O     . ARG B 2 367 ? 204.560 168.549 215.905 1.00 96.91  ? 370 ARG C O     1 
ATOM   5626 C CB    . ARG B 2 367 ? 202.500 166.494 216.180 1.00 96.91  ? 370 ARG C CB    1 
ATOM   5627 C CG    . ARG B 2 367 ? 201.587 167.456 215.448 1.00 96.91  ? 370 ARG C CG    1 
ATOM   5628 C CD    . ARG B 2 367 ? 200.133 167.039 215.595 1.00 96.91  ? 370 ARG C CD    1 
ATOM   5629 N NE    . ARG B 2 367 ? 199.759 166.840 216.992 1.00 96.91  ? 370 ARG C NE    1 
ATOM   5630 C CZ    . ARG B 2 367 ? 199.502 167.824 217.847 1.00 96.91  ? 370 ARG C CZ    1 
ATOM   5631 N NH1   . ARG B 2 367 ? 199.579 169.087 217.451 1.00 96.91  ? 370 ARG C NH1   1 
ATOM   5632 N NH2   . ARG B 2 367 ? 199.169 167.547 219.099 1.00 96.91  ? 370 ARG C NH2   1 
ATOM   5633 N N     . GLU B 2 368 ? 205.951 166.963 216.658 1.00 91.86  ? 371 GLU C N     1 
ATOM   5634 C CA    . GLU B 2 368 ? 206.915 167.895 217.225 1.00 91.86  ? 371 GLU C CA    1 
ATOM   5635 C C     . GLU B 2 368 ? 208.253 167.755 216.507 1.00 91.86  ? 371 GLU C C     1 
ATOM   5636 O O     . GLU B 2 368 ? 208.385 167.031 215.517 1.00 91.86  ? 371 GLU C O     1 
ATOM   5637 C CB    . GLU B 2 368 ? 207.080 167.663 218.729 1.00 91.86  ? 371 GLU C CB    1 
ATOM   5638 C CG    . GLU B 2 368 ? 205.783 167.396 219.464 1.00 91.86  ? 371 GLU C CG    1 
ATOM   5639 C CD    . GLU B 2 368 ? 206.013 166.932 220.887 1.00 91.86  ? 371 GLU C CD    1 
ATOM   5640 O OE1   . GLU B 2 368 ? 207.187 166.754 221.272 1.00 91.86  ? 371 GLU C OE1   1 
ATOM   5641 O OE2   . GLU B 2 368 ? 205.021 166.745 221.622 1.00 91.86  ? 371 GLU C OE2   1 
ATOM   5642 N N     . GLU B 2 369 ? 209.258 168.461 217.027 1.00 85.44  ? 372 GLU C N     1 
ATOM   5643 C CA    . GLU B 2 369 ? 210.591 168.494 216.437 1.00 85.44  ? 372 GLU C CA    1 
ATOM   5644 C C     . GLU B 2 369 ? 211.658 168.001 217.407 1.00 85.44  ? 372 GLU C C     1 
ATOM   5645 O O     . GLU B 2 369 ? 212.842 168.293 217.222 1.00 85.44  ? 372 GLU C O     1 
ATOM   5646 C CB    . GLU B 2 369 ? 210.929 169.906 215.953 1.00 85.44  ? 372 GLU C CB    1 
ATOM   5647 C CG    . GLU B 2 369 ? 210.941 170.975 217.047 1.00 85.44  ? 372 GLU C CG    1 
ATOM   5648 C CD    . GLU B 2 369 ? 209.555 171.337 217.558 1.00 85.44  ? 372 GLU C CD    1 
ATOM   5649 O OE1   . GLU B 2 369 ? 209.464 171.974 218.627 1.00 85.44  ? 372 GLU C OE1   1 
ATOM   5650 O OE2   . GLU B 2 369 ? 208.559 170.986 216.892 1.00 85.44  ? 372 GLU C OE2   1 
ATOM   5651 N N     . GLN B 2 370 ? 211.261 167.264 218.438 1.00 79.67  ? 373 GLN C N     1 
ATOM   5652 C CA    . GLN B 2 370 ? 212.192 166.726 219.416 1.00 79.67  ? 373 GLN C CA    1 
ATOM   5653 C C     . GLN B 2 370 ? 212.548 165.291 219.056 1.00 79.67  ? 373 GLN C C     1 
ATOM   5654 O O     . GLN B 2 370 ? 211.714 164.544 218.538 1.00 79.67  ? 373 GLN C O     1 
ATOM   5655 C CB    . GLN B 2 370 ? 211.585 166.783 220.817 1.00 79.67  ? 373 GLN C CB    1 
ATOM   5656 C CG    . GLN B 2 370 ? 212.524 166.359 221.922 1.00 79.67  ? 373 GLN C CG    1 
ATOM   5657 C CD    . GLN B 2 370 ? 213.641 167.348 222.132 1.00 79.67  ? 373 GLN C CD    1 
ATOM   5658 O OE1   . GLN B 2 370 ? 213.467 168.547 221.925 1.00 79.67  ? 373 GLN C OE1   1 
ATOM   5659 N NE2   . GLN B 2 370 ? 214.800 166.854 222.541 1.00 79.67  ? 373 GLN C NE2   1 
ATOM   5660 N N     . ALA B 2 371 ? 213.792 164.911 219.327 1.00 78.83  ? 374 ALA C N     1 
ATOM   5661 C CA    . ALA B 2 371 ? 214.259 163.569 219.013 1.00 78.83  ? 374 ALA C CA    1 
ATOM   5662 C C     . ALA B 2 371 ? 213.929 162.615 220.150 1.00 78.83  ? 374 ALA C C     1 
ATOM   5663 O O     . ALA B 2 371 ? 214.135 162.938 221.323 1.00 78.83  ? 374 ALA C O     1 
ATOM   5664 C CB    . ALA B 2 371 ? 215.763 163.575 218.750 1.00 78.83  ? 374 ALA C CB    1 
ATOM   5665 N N     . GLU B 2 372 ? 213.413 161.443 219.802 1.00 82.85  ? 375 GLU C N     1 
ATOM   5666 C CA    . GLU B 2 372 ? 213.164 160.383 220.762 1.00 82.85  ? 375 GLU C CA    1 
ATOM   5667 C C     . GLU B 2 372 ? 213.614 159.056 220.174 1.00 82.85  ? 375 GLU C C     1 
ATOM   5668 O O     . GLU B 2 372 ? 213.497 158.836 218.965 1.00 82.85  ? 375 GLU C O     1 
ATOM   5669 C CB    . GLU B 2 372 ? 211.681 160.308 221.147 1.00 82.85  ? 375 GLU C CB    1 
ATOM   5670 C CG    . GLU B 2 372 ? 210.753 159.936 220.012 1.00 82.85  ? 375 GLU C CG    1 
ATOM   5671 C CD    . GLU B 2 372 ? 209.316 159.806 220.465 1.00 82.85  ? 375 GLU C CD    1 
ATOM   5672 O OE1   . GLU B 2 372 ? 209.035 160.124 221.639 1.00 82.85  ? 375 GLU C OE1   1 
ATOM   5673 O OE2   . GLU B 2 372 ? 208.468 159.389 219.651 1.00 82.85  ? 375 GLU C OE2   1 
ATOM   5674 N N     . PRO B 2 373 ? 214.141 158.159 221.000 1.00 80.61  ? 376 PRO C N     1 
ATOM   5675 C CA    . PRO B 2 373 ? 214.744 156.935 220.465 1.00 80.61  ? 376 PRO C CA    1 
ATOM   5676 C C     . PRO B 2 373 ? 213.703 155.912 220.047 1.00 80.61  ? 376 PRO C C     1 
ATOM   5677 O O     . PRO B 2 373 ? 212.706 155.689 220.736 1.00 80.61  ? 376 PRO C O     1 
ATOM   5678 C CB    . PRO B 2 373 ? 215.579 156.419 221.641 1.00 80.61  ? 376 PRO C CB    1 
ATOM   5679 C CG    . PRO B 2 373 ? 214.861 156.920 222.837 1.00 80.61  ? 376 PRO C CG    1 
ATOM   5680 C CD    . PRO B 2 373 ? 214.290 158.255 222.461 1.00 80.61  ? 376 PRO C CD    1 
ATOM   5681 N N     . ASP B 2 374 ? 213.948 155.285 218.899 1.00 84.10  ? 377 ASP C N     1 
ATOM   5682 C CA    . ASP B 2 374 ? 213.165 154.142 218.442 1.00 84.10  ? 377 ASP C CA    1 
ATOM   5683 C C     . ASP B 2 374 ? 214.095 152.937 218.393 1.00 84.10  ? 377 ASP C C     1 
ATOM   5684 O O     . ASP B 2 374 ? 214.989 152.863 217.543 1.00 84.10  ? 377 ASP C O     1 
ATOM   5685 C CB    . ASP B 2 374 ? 212.505 154.412 217.088 1.00 84.10  ? 377 ASP C CB    1 
ATOM   5686 C CG    . ASP B 2 374 ? 213.502 154.705 215.992 1.00 84.10  ? 377 ASP C CG    1 
ATOM   5687 O OD1   . ASP B 2 374 ? 214.513 155.377 216.274 1.00 84.10  ? 377 ASP C OD1   1 
ATOM   5688 O OD2   . ASP B 2 374 ? 213.276 154.261 214.847 1.00 84.10  ? 377 ASP C OD2   1 
ATOM   5689 N N     . GLY B 2 375 ? 213.893 152.003 219.315 1.00 87.54  ? 378 GLY C N     1 
ATOM   5690 C CA    . GLY B 2 375 ? 214.806 150.892 219.463 1.00 87.54  ? 378 GLY C CA    1 
ATOM   5691 C C     . GLY B 2 375 ? 215.916 151.222 220.436 1.00 87.54  ? 378 GLY C C     1 
ATOM   5692 O O     . GLY B 2 375 ? 216.676 152.172 220.227 1.00 87.54  ? 378 GLY C O     1 
ATOM   5693 N N     . THR B 2 376 ? 216.018 150.443 221.511 1.00 86.44  ? 379 THR C N     1 
ATOM   5694 C CA    . THR B 2 376 ? 217.017 150.672 222.545 1.00 86.44  ? 379 THR C CA    1 
ATOM   5695 C C     . THR B 2 376 ? 218.041 149.549 222.618 1.00 86.44  ? 379 THR C C     1 
ATOM   5696 O O     . THR B 2 376 ? 218.803 149.482 223.589 1.00 86.44  ? 379 THR C O     1 
ATOM   5697 C CB    . THR B 2 376 ? 216.339 150.853 223.906 1.00 86.44  ? 379 THR C CB    1 
ATOM   5698 O OG1   . THR B 2 376 ? 215.795 149.601 224.339 1.00 86.44  ? 379 THR C OG1   1 
ATOM   5699 C CG2   . THR B 2 376 ? 215.219 151.870 223.808 1.00 86.44  ? 379 THR C CG2   1 
ATOM   5700 N N     . GLU B 2 377 ? 218.084 148.669 221.617 1.00 86.27  ? 380 GLU C N     1 
ATOM   5701 C CA    . GLU B 2 377 ? 218.974 147.515 221.671 1.00 86.27  ? 380 GLU C CA    1 
ATOM   5702 C C     . GLU B 2 377 ? 220.435 147.946 221.670 1.00 86.27  ? 380 GLU C C     1 
ATOM   5703 O O     . GLU B 2 377 ? 221.212 147.567 222.554 1.00 86.27  ? 380 GLU C O     1 
ATOM   5704 C CB    . GLU B 2 377 ? 218.681 146.581 220.498 1.00 86.27  ? 380 GLU C CB    1 
ATOM   5705 C CG    . GLU B 2 377 ? 217.199 146.380 220.230 1.00 86.27  ? 380 GLU C CG    1 
ATOM   5706 C CD    . GLU B 2 377 ? 216.413 146.055 221.486 1.00 86.27  ? 380 GLU C CD    1 
ATOM   5707 O OE1   . GLU B 2 377 ? 216.859 145.182 222.260 1.00 86.27  ? 380 GLU C OE1   1 
ATOM   5708 O OE2   . GLU B 2 377 ? 215.349 146.676 221.700 1.00 86.27  ? 380 GLU C OE2   1 
ATOM   5709 N N     . ASP B 2 378 ? 220.832 148.732 220.669 1.00 82.15  ? 381 ASP C N     1 
ATOM   5710 C CA    . ASP B 2 378 ? 222.199 149.237 220.638 1.00 82.15  ? 381 ASP C CA    1 
ATOM   5711 C C     . ASP B 2 378 ? 222.484 150.124 221.837 1.00 82.15  ? 381 ASP C C     1 
ATOM   5712 O O     . ASP B 2 378 ? 223.601 150.114 222.363 1.00 82.15  ? 381 ASP C O     1 
ATOM   5713 C CB    . ASP B 2 378 ? 222.444 149.994 219.338 1.00 82.15  ? 381 ASP C CB    1 
ATOM   5714 C CG    . ASP B 2 378 ? 222.124 149.160 218.116 1.00 82.15  ? 381 ASP C CG    1 
ATOM   5715 O OD1   . ASP B 2 378 ? 222.978 148.349 217.701 1.00 82.15  ? 381 ASP C OD1   1 
ATOM   5716 O OD2   . ASP B 2 378 ? 221.010 149.312 217.573 1.00 82.15  ? 381 ASP C OD2   1 
ATOM   5717 N N     . ALA B 2 379 ? 221.486 150.879 222.297 1.00 82.07  ? 382 ALA C N     1 
ATOM   5718 C CA    . ALA B 2 379 ? 221.647 151.643 223.528 1.00 82.07  ? 382 ALA C CA    1 
ATOM   5719 C C     . ALA B 2 379 ? 221.859 150.721 224.719 1.00 82.07  ? 382 ALA C C     1 
ATOM   5720 O O     . ALA B 2 379 ? 222.706 150.990 225.577 1.00 82.07  ? 382 ALA C O     1 
ATOM   5721 C CB    . ALA B 2 379 ? 220.432 152.540 223.757 1.00 82.07  ? 382 ALA C CB    1 
ATOM   5722 N N     . ASP B 2 380 ? 221.105 149.622 224.783 1.00 82.36  ? 383 ASP C N     1 
ATOM   5723 C CA    . ASP B 2 380 ? 221.285 148.659 225.864 1.00 82.36  ? 383 ASP C CA    1 
ATOM   5724 C C     . ASP B 2 380 ? 222.698 148.095 225.864 1.00 82.36  ? 383 ASP C C     1 
ATOM   5725 O O     . ASP B 2 380 ? 223.366 148.057 226.904 1.00 82.36  ? 383 ASP C O     1 
ATOM   5726 C CB    . ASP B 2 380 ? 220.261 147.531 225.737 1.00 82.36  ? 383 ASP C CB    1 
ATOM   5727 C CG    . ASP B 2 380 ? 218.884 147.934 226.218 1.00 82.36  ? 383 ASP C CG    1 
ATOM   5728 O OD1   . ASP B 2 380 ? 217.895 147.295 225.800 1.00 82.36  ? 383 ASP C OD1   1 
ATOM   5729 O OD2   . ASP B 2 380 ? 218.788 148.890 227.015 1.00 82.36  ? 383 ASP C OD2   1 
ATOM   5730 N N     . LYS B 2 381 ? 223.178 147.664 224.697 1.00 77.50  ? 384 LYS C N     1 
ATOM   5731 C CA    . LYS B 2 381 ? 224.501 147.056 224.619 1.00 77.50  ? 384 LYS C CA    1 
ATOM   5732 C C     . LYS B 2 381 ? 225.595 148.065 224.944 1.00 77.50  ? 384 LYS C C     1 
ATOM   5733 O O     . LYS B 2 381 ? 226.530 147.761 225.691 1.00 77.50  ? 384 LYS C O     1 
ATOM   5734 C CB    . LYS B 2 381 ? 224.719 146.450 223.235 1.00 77.50  ? 384 LYS C CB    1 
ATOM   5735 C CG    . LYS B 2 381 ? 223.752 145.339 222.895 1.00 77.50  ? 384 LYS C CG    1 
ATOM   5736 C CD    . LYS B 2 381 ? 223.834 144.990 221.424 1.00 77.50  ? 384 LYS C CD    1 
ATOM   5737 C CE    . LYS B 2 381 ? 222.650 144.152 220.993 1.00 77.50  ? 384 LYS C CE    1 
ATOM   5738 N NZ    . LYS B 2 381 ? 222.440 144.238 219.524 1.00 77.50  ? 384 LYS C NZ    1 
ATOM   5739 N N     . SER B 2 382 ? 225.494 149.280 224.398 1.00 74.01  ? 385 SER C N     1 
ATOM   5740 C CA    . SER B 2 382 ? 226.517 150.282 224.664 1.00 74.01  ? 385 SER C CA    1 
ATOM   5741 C C     . SER B 2 382 ? 226.523 150.710 226.126 1.00 74.01  ? 385 SER C C     1 
ATOM   5742 O O     . SER B 2 382 ? 227.596 150.903 226.707 1.00 74.01  ? 385 SER C O     1 
ATOM   5743 C CB    . SER B 2 382 ? 226.309 151.489 223.753 1.00 74.01  ? 385 SER C CB    1 
ATOM   5744 O OG    . SER B 2 382 ? 226.954 152.637 224.268 1.00 74.01  ? 385 SER C OG    1 
ATOM   5745 N N     . ALA B 2 383 ? 225.347 150.838 226.745 1.00 73.95  ? 386 ALA C N     1 
ATOM   5746 C CA    . ALA B 2 383 ? 225.294 151.237 228.145 1.00 73.95  ? 386 ALA C CA    1 
ATOM   5747 C C     . ALA B 2 383 ? 225.759 150.115 229.060 1.00 73.95  ? 386 ALA C C     1 
ATOM   5748 O O     . ALA B 2 383 ? 226.305 150.374 230.137 1.00 73.95  ? 386 ALA C O     1 
ATOM   5749 C CB    . ALA B 2 383 ? 223.880 151.673 228.513 1.00 73.95  ? 386 ALA C CB    1 
ATOM   5750 N N     . TYR B 2 384 ? 225.543 148.861 228.660 1.00 73.60  ? 387 TYR C N     1 
ATOM   5751 C CA    . TYR B 2 384 ? 226.025 147.752 229.473 1.00 73.60  ? 387 TYR C CA    1 
ATOM   5752 C C     . TYR B 2 384 ? 227.530 147.576 229.336 1.00 73.60  ? 387 TYR C C     1 
ATOM   5753 O O     . TYR B 2 384 ? 228.194 147.170 230.295 1.00 73.60  ? 387 TYR C O     1 
ATOM   5754 C CB    . TYR B 2 384 ? 225.291 146.469 229.092 1.00 73.60  ? 387 TYR C CB    1 
ATOM   5755 C CG    . TYR B 2 384 ? 226.094 145.213 229.306 1.00 73.60  ? 387 TYR C CG    1 
ATOM   5756 C CD1   . TYR B 2 384 ? 226.655 144.540 228.235 1.00 73.60  ? 387 TYR C CD1   1 
ATOM   5757 C CD2   . TYR B 2 384 ? 226.280 144.695 230.577 1.00 73.60  ? 387 TYR C CD2   1 
ATOM   5758 C CE1   . TYR B 2 384 ? 227.387 143.393 228.422 1.00 73.60  ? 387 TYR C CE1   1 
ATOM   5759 C CE2   . TYR B 2 384 ? 227.011 143.546 230.774 1.00 73.60  ? 387 TYR C CE2   1 
ATOM   5760 C CZ    . TYR B 2 384 ? 227.562 142.899 229.691 1.00 73.60  ? 387 TYR C CZ    1 
ATOM   5761 O OH    . TYR B 2 384 ? 228.293 141.752 229.877 1.00 73.60  ? 387 TYR C OH    1 
ATOM   5762 N N     . LEU B 2 385 ? 228.086 147.875 228.161 1.00 71.68  ? 388 LEU C N     1 
ATOM   5763 C CA    . LEU B 2 385 ? 229.534 147.812 227.992 1.00 71.68  ? 388 LEU C CA    1 
ATOM   5764 C C     . LEU B 2 385 ? 230.220 148.943 228.747 1.00 71.68  ? 388 LEU C C     1 
ATOM   5765 O O     . LEU B 2 385 ? 231.109 148.706 229.571 1.00 71.68  ? 388 LEU C O     1 
ATOM   5766 C CB    . LEU B 2 385 ? 229.899 147.858 226.509 1.00 71.68  ? 388 LEU C CB    1 
ATOM   5767 C CG    . LEU B 2 385 ? 229.594 146.619 225.672 1.00 71.68  ? 388 LEU C CG    1 
ATOM   5768 C CD1   . LEU B 2 385 ? 230.338 146.690 224.358 1.00 71.68  ? 388 LEU C CD1   1 
ATOM   5769 C CD2   . LEU B 2 385 ? 229.952 145.353 226.424 1.00 71.68  ? 388 LEU C CD2   1 
ATOM   5770 N N     . MET B 2 386 ? 229.825 150.186 228.471 1.00 72.12  ? 389 MET C N     1 
ATOM   5771 C CA    . MET B 2 386 ? 230.444 151.327 229.134 1.00 72.12  ? 389 MET C CA    1 
ATOM   5772 C C     . MET B 2 386 ? 230.145 151.387 230.624 1.00 72.12  ? 389 MET C C     1 
ATOM   5773 O O     . MET B 2 386 ? 230.695 152.254 231.311 1.00 72.12  ? 389 MET C O     1 
ATOM   5774 C CB    . MET B 2 386 ? 229.988 152.624 228.474 1.00 72.12  ? 389 MET C CB    1 
ATOM   5775 C CG    . MET B 2 386 ? 230.562 152.845 227.098 1.00 72.12  ? 389 MET C CG    1 
ATOM   5776 S SD    . MET B 2 386 ? 230.096 154.450 226.443 1.00 72.12  ? 389 MET C SD    1 
ATOM   5777 C CE    . MET B 2 386 ? 228.314 154.360 226.559 1.00 72.12  ? 389 MET C CE    1 
ATOM   5778 N N     . GLY B 2 387 ? 229.305 150.498 231.141 1.00 71.34  ? 390 GLY C N     1 
ATOM   5779 C CA    . GLY B 2 387 ? 228.943 150.549 232.541 1.00 71.34  ? 390 GLY C CA    1 
ATOM   5780 C C     . GLY B 2 387 ? 228.137 151.784 232.874 1.00 71.34  ? 390 GLY C C     1 
ATOM   5781 O O     . GLY B 2 387 ? 228.529 152.578 233.731 1.00 71.34  ? 390 GLY C O     1 
ATOM   5782 N N     . LEU B 2 388 ? 227.011 151.963 232.190 1.00 70.85  ? 391 LEU C N     1 
ATOM   5783 C CA    . LEU B 2 388 ? 226.134 153.098 232.442 1.00 70.85  ? 391 LEU C CA    1 
ATOM   5784 C C     . LEU B 2 388 ? 224.697 152.627 232.591 1.00 70.85  ? 391 LEU C C     1 
ATOM   5785 O O     . LEU B 2 388 ? 224.437 151.423 232.674 1.00 70.85  ? 391 LEU C O     1 
ATOM   5786 C CB    . LEU B 2 388 ? 226.227 154.126 231.315 1.00 70.85  ? 391 LEU C CB    1 
ATOM   5787 C CG    . LEU B 2 388 ? 227.575 154.804 231.100 1.00 70.85  ? 391 LEU C CG    1 
ATOM   5788 C CD1   . LEU B 2 388 ? 227.515 155.729 229.899 1.00 70.85  ? 391 LEU C CD1   1 
ATOM   5789 C CD2   . LEU B 2 388 ? 227.986 155.560 232.343 1.00 70.85  ? 391 LEU C CD2   1 
ATOM   5790 N N     . ASN B 2 389 ? 223.762 153.568 232.625 1.00 73.44  ? 392 ASN C N     1 
ATOM   5791 C CA    . ASN B 2 389 ? 222.340 153.261 232.647 1.00 73.44  ? 392 ASN C CA    1 
ATOM   5792 C C     . ASN B 2 389 ? 221.733 153.649 231.306 1.00 73.44  ? 392 ASN C C     1 
ATOM   5793 O O     . ASN B 2 389 ? 221.893 154.787 230.853 1.00 73.44  ? 392 ASN C O     1 
ATOM   5794 C CB    . ASN B 2 389 ? 221.641 153.997 233.789 1.00 73.44  ? 392 ASN C CB    1 
ATOM   5795 C CG    . ASN B 2 389 ? 220.284 153.415 234.108 1.00 73.44  ? 392 ASN C CG    1 
ATOM   5796 O OD1   . ASN B 2 389 ? 219.824 152.488 233.444 1.00 73.44  ? 392 ASN C OD1   1 
ATOM   5797 N ND2   . ASN B 2 389 ? 219.637 153.949 235.134 1.00 73.44  ? 392 ASN C ND2   1 
ATOM   5798 N N     . SER B 2 390 ? 221.035 152.704 230.676 1.00 73.64  ? 393 SER C N     1 
ATOM   5799 C CA    . SER B 2 390 ? 220.532 152.929 229.325 1.00 73.64  ? 393 SER C CA    1 
ATOM   5800 C C     . SER B 2 390 ? 219.507 154.056 229.296 1.00 73.64  ? 393 SER C C     1 
ATOM   5801 O O     . SER B 2 390 ? 219.549 154.925 228.416 1.00 73.64  ? 393 SER C O     1 
ATOM   5802 C CB    . SER B 2 390 ? 219.933 151.638 228.774 1.00 73.64  ? 393 SER C CB    1 
ATOM   5803 O OG    . SER B 2 390 ? 218.802 151.248 229.529 1.00 73.64  ? 393 SER C OG    1 
ATOM   5804 N N     . ALA B 2 391 ? 218.581 154.062 230.256 1.00 74.59  ? 394 ALA C N     1 
ATOM   5805 C CA    . ALA B 2 391 ? 217.586 155.127 230.309 1.00 74.59  ? 394 ALA C CA    1 
ATOM   5806 C C     . ALA B 2 391 ? 218.241 156.480 230.548 1.00 74.59  ? 394 ALA C C     1 
ATOM   5807 O O     . ALA B 2 391 ? 217.860 157.480 229.929 1.00 74.59  ? 394 ALA C O     1 
ATOM   5808 C CB    . ALA B 2 391 ? 216.555 154.829 231.395 1.00 74.59  ? 394 ALA C CB    1 
ATOM   5809 N N     . ASP B 2 392 ? 219.245 156.529 231.427 1.00 72.82  ? 395 ASP C N     1 
ATOM   5810 C CA    . ASP B 2 392 ? 219.928 157.791 231.689 1.00 72.82  ? 395 ASP C CA    1 
ATOM   5811 C C     . ASP B 2 392 ? 220.725 158.248 230.477 1.00 72.82  ? 395 ASP C C     1 
ATOM   5812 O O     . ASP B 2 392 ? 220.761 159.444 230.171 1.00 72.82  ? 395 ASP C O     1 
ATOM   5813 C CB    . ASP B 2 392 ? 220.838 157.659 232.908 1.00 72.82  ? 395 ASP C CB    1 
ATOM   5814 C CG    . ASP B 2 392 ? 220.064 157.600 234.208 1.00 72.82  ? 395 ASP C CG    1 
ATOM   5815 O OD1   . ASP B 2 392 ? 218.820 157.515 234.155 1.00 72.82  ? 395 ASP C OD1   1 
ATOM   5816 O OD2   . ASP B 2 392 ? 220.700 157.642 235.283 1.00 72.82  ? 395 ASP C OD2   1 
ATOM   5817 N N     . LEU B 2 393 ? 221.358 157.314 229.766 1.00 68.70  ? 396 LEU C N     1 
ATOM   5818 C CA    . LEU B 2 393 ? 222.091 157.677 228.558 1.00 68.70  ? 396 LEU C CA    1 
ATOM   5819 C C     . LEU B 2 393 ? 221.155 158.248 227.502 1.00 68.70  ? 396 LEU C C     1 
ATOM   5820 O O     . LEU B 2 393 ? 221.452 159.273 226.878 1.00 68.70  ? 396 LEU C O     1 
ATOM   5821 C CB    . LEU B 2 393 ? 222.839 156.463 228.013 1.00 68.70  ? 396 LEU C CB    1 
ATOM   5822 C CG    . LEU B 2 393 ? 223.531 156.671 226.667 1.00 68.70  ? 396 LEU C CG    1 
ATOM   5823 C CD1   . LEU B 2 393 ? 224.827 157.435 226.845 1.00 68.70  ? 396 LEU C CD1   1 
ATOM   5824 C CD2   . LEU B 2 393 ? 223.781 155.338 225.991 1.00 68.70  ? 396 LEU C CD2   1 
ATOM   5825 N N     . LEU B 2 394 ? 220.015 157.591 227.285 1.00 70.01  ? 397 LEU C N     1 
ATOM   5826 C CA    . LEU B 2 394 ? 219.064 158.089 226.298 1.00 70.01  ? 397 LEU C CA    1 
ATOM   5827 C C     . LEU B 2 394 ? 218.520 159.454 226.696 1.00 70.01  ? 397 LEU C C     1 
ATOM   5828 O O     . LEU B 2 394 ? 218.420 160.360 225.859 1.00 70.01  ? 397 LEU C O     1 
ATOM   5829 C CB    . LEU B 2 394 ? 217.929 157.086 226.116 1.00 70.01  ? 397 LEU C CB    1 
ATOM   5830 C CG    . LEU B 2 394 ? 218.362 155.747 225.523 1.00 70.01  ? 397 LEU C CG    1 
ATOM   5831 C CD1   . LEU B 2 394 ? 217.168 154.838 225.329 1.00 70.01  ? 397 LEU C CD1   1 
ATOM   5832 C CD2   . LEU B 2 394 ? 219.095 155.959 224.213 1.00 70.01  ? 397 LEU C CD2   1 
ATOM   5833 N N     . LYS B 2 395 ? 218.176 159.628 227.974 1.00 70.21  ? 398 LYS C N     1 
ATOM   5834 C CA    . LYS B 2 395 ? 217.647 160.909 228.424 1.00 70.21  ? 398 LYS C CA    1 
ATOM   5835 C C     . LYS B 2 395 ? 218.696 162.008 228.318 1.00 70.21  ? 398 LYS C C     1 
ATOM   5836 O O     . LYS B 2 395 ? 218.361 163.171 228.065 1.00 70.21  ? 398 LYS C O     1 
ATOM   5837 C CB    . LYS B 2 395 ? 217.137 160.784 229.857 1.00 70.21  ? 398 LYS C CB    1 
ATOM   5838 C CG    . LYS B 2 395 ? 216.308 161.959 230.326 1.00 70.21  ? 398 LYS C CG    1 
ATOM   5839 C CD    . LYS B 2 395 ? 216.026 161.861 231.813 1.00 70.21  ? 398 LYS C CD    1 
ATOM   5840 C CE    . LYS B 2 395 ? 217.317 161.870 232.614 1.00 70.21  ? 398 LYS C CE    1 
ATOM   5841 N NZ    . LYS B 2 395 ? 217.138 161.253 233.958 1.00 70.21  ? 398 LYS C NZ    1 
ATOM   5842 N N     . GLY B 2 396 ? 219.971 161.664 228.504 1.00 66.95  ? 399 GLY C N     1 
ATOM   5843 C CA    . GLY B 2 396 ? 221.017 162.662 228.385 1.00 66.95  ? 399 GLY C CA    1 
ATOM   5844 C C     . GLY B 2 396 ? 221.349 163.004 226.949 1.00 66.95  ? 399 GLY C C     1 
ATOM   5845 O O     . GLY B 2 396 ? 221.766 164.128 226.657 1.00 66.95  ? 399 GLY C O     1 
ATOM   5846 N N     . LEU B 2 397 ? 221.178 162.050 226.036 1.00 67.27  ? 400 LEU C N     1 
ATOM   5847 C CA    . LEU B 2 397 ? 221.380 162.352 224.625 1.00 67.27  ? 400 LEU C CA    1 
ATOM   5848 C C     . LEU B 2 397 ? 220.235 163.188 224.068 1.00 67.27  ? 400 LEU C C     1 
ATOM   5849 O O     . LEU B 2 397 ? 220.464 164.107 223.275 1.00 67.27  ? 400 LEU C O     1 
ATOM   5850 C CB    . LEU B 2 397 ? 221.532 161.063 223.819 1.00 67.27  ? 400 LEU C CB    1 
ATOM   5851 C CG    . LEU B 2 397 ? 222.876 160.343 223.909 1.00 67.27  ? 400 LEU C CG    1 
ATOM   5852 C CD1   . LEU B 2 397 ? 222.784 158.980 223.257 1.00 67.27  ? 400 LEU C CD1   1 
ATOM   5853 C CD2   . LEU B 2 397 ? 223.970 161.168 223.266 1.00 67.27  ? 400 LEU C CD2   1 
ATOM   5854 N N     . CYS B 2 398 ? 219.001 162.889 224.475 1.00 70.15  ? 401 CYS C N     1 
ATOM   5855 C CA    . CYS B 2 398 ? 217.843 163.606 223.956 1.00 70.15  ? 401 CYS C CA    1 
ATOM   5856 C C     . CYS B 2 398 ? 217.574 164.915 224.683 1.00 70.15  ? 401 CYS C C     1 
ATOM   5857 O O     . CYS B 2 398 ? 217.154 165.887 224.047 1.00 70.15  ? 401 CYS C O     1 
ATOM   5858 C CB    . CYS B 2 398 ? 216.598 162.722 224.034 1.00 70.15  ? 401 CYS C CB    1 
ATOM   5859 S SG    . CYS B 2 398 ? 216.782 161.109 223.258 1.00 70.15  ? 401 CYS C SG    1 
ATOM   5860 N N     . HIS B 2 399 ? 217.807 164.972 225.991 1.00 69.30  ? 402 HIS C N     1 
ATOM   5861 C CA    . HIS B 2 399 ? 217.458 166.133 226.810 1.00 69.30  ? 402 HIS C CA    1 
ATOM   5862 C C     . HIS B 2 399 ? 218.665 166.576 227.625 1.00 69.30  ? 402 HIS C C     1 
ATOM   5863 O O     . HIS B 2 399 ? 218.715 166.376 228.843 1.00 69.30  ? 402 HIS C O     1 
ATOM   5864 C CB    . HIS B 2 399 ? 216.276 165.813 227.724 1.00 69.30  ? 402 HIS C CB    1 
ATOM   5865 C CG    . HIS B 2 399 ? 215.029 165.439 226.989 1.00 69.30  ? 402 HIS C CG    1 
ATOM   5866 N ND1   . HIS B 2 399 ? 214.265 166.359 226.305 1.00 69.30  ? 402 HIS C ND1   1 
ATOM   5867 C CD2   . HIS B 2 399 ? 214.414 164.245 226.827 1.00 69.30  ? 402 HIS C CD2   1 
ATOM   5868 C CE1   . HIS B 2 399 ? 213.232 165.747 225.755 1.00 69.30  ? 402 HIS C CE1   1 
ATOM   5869 N NE2   . HIS B 2 399 ? 213.299 164.463 226.056 1.00 69.30  ? 402 HIS C NE2   1 
ATOM   5870 N N     . PRO B 2 400 ? 219.656 167.191 226.984 1.00 67.42  ? 403 PRO C N     1 
ATOM   5871 C CA    . PRO B 2 400 ? 220.819 167.676 227.731 1.00 67.42  ? 403 PRO C CA    1 
ATOM   5872 C C     . PRO B 2 400 ? 220.451 168.856 228.611 1.00 67.42  ? 403 PRO C C     1 
ATOM   5873 O O     . PRO B 2 400 ? 219.534 169.619 228.304 1.00 67.42  ? 403 PRO C O     1 
ATOM   5874 C CB    . PRO B 2 400 ? 221.795 168.089 226.627 1.00 67.42  ? 403 PRO C CB    1 
ATOM   5875 C CG    . PRO B 2 400 ? 220.911 168.470 225.505 1.00 67.42  ? 403 PRO C CG    1 
ATOM   5876 C CD    . PRO B 2 400 ? 219.767 167.500 225.551 1.00 67.42  ? 403 PRO C CD    1 
ATOM   5877 N N     . GLN B 2 401 ? 221.175 169.003 229.712 1.00 68.39  ? 404 GLN C N     1 
ATOM   5878 C CA    . GLN B 2 401 ? 220.979 170.122 230.617 1.00 68.39  ? 404 GLN C CA    1 
ATOM   5879 C C     . GLN B 2 401 ? 222.094 171.142 230.448 1.00 68.39  ? 404 GLN C C     1 
ATOM   5880 O O     . GLN B 2 401 ? 223.198 170.826 230.002 1.00 68.39  ? 404 GLN C O     1 
ATOM   5881 C CB    . GLN B 2 401 ? 220.922 169.649 232.069 1.00 68.39  ? 404 GLN C CB    1 
ATOM   5882 C CG    . GLN B 2 401 ? 219.644 168.923 232.428 1.00 68.39  ? 404 GLN C CG    1 
ATOM   5883 C CD    . GLN B 2 401 ? 219.514 168.693 233.916 1.00 68.39  ? 404 GLN C CD    1 
ATOM   5884 O OE1   . GLN B 2 401 ? 220.370 168.062 234.534 1.00 68.39  ? 404 GLN C OE1   1 
ATOM   5885 N NE2   . GLN B 2 401 ? 218.441 169.209 234.502 1.00 68.39  ? 404 GLN C NE2   1 
ATOM   5886 N N     . VAL B 2 402 ? 221.784 172.384 230.807 1.00 68.30  ? 405 VAL C N     1 
ATOM   5887 C CA    . VAL B 2 402 ? 222.720 173.494 230.704 1.00 68.30  ? 405 VAL C CA    1 
ATOM   5888 C C     . VAL B 2 402 ? 222.606 174.311 231.982 1.00 68.30  ? 405 VAL C C     1 
ATOM   5889 O O     . VAL B 2 402 ? 221.527 174.424 232.569 1.00 68.30  ? 405 VAL C O     1 
ATOM   5890 C CB    . VAL B 2 402 ? 222.437 174.366 229.456 1.00 68.30  ? 405 VAL C CB    1 
ATOM   5891 C CG1   . VAL B 2 402 ? 223.402 175.517 229.373 1.00 68.30  ? 405 VAL C CG1   1 
ATOM   5892 C CG2   . VAL B 2 402 ? 222.509 173.537 228.189 1.00 68.30  ? 405 VAL C CG2   1 
ATOM   5893 N N     . LYS B 2 403 ? 223.727 174.877 232.422 1.00 68.29  ? 406 LYS C N     1 
ATOM   5894 C CA    . LYS B 2 403 ? 223.768 175.677 233.641 1.00 68.29  ? 406 LYS C CA    1 
ATOM   5895 C C     . LYS B 2 403 ? 223.644 177.149 233.268 1.00 68.29  ? 406 LYS C C     1 
ATOM   5896 O O     . LYS B 2 403 ? 224.591 177.749 232.752 1.00 68.29  ? 406 LYS C O     1 
ATOM   5897 C CB    . LYS B 2 403 ? 225.050 175.417 234.427 1.00 68.29  ? 406 LYS C CB    1 
ATOM   5898 C CG    . LYS B 2 403 ? 225.092 176.139 235.763 1.00 68.29  ? 406 LYS C CG    1 
ATOM   5899 C CD    . LYS B 2 403 ? 226.252 175.680 236.620 1.00 68.29  ? 406 LYS C CD    1 
ATOM   5900 C CE    . LYS B 2 403 ? 226.245 176.386 237.963 1.00 68.29  ? 406 LYS C CE    1 
ATOM   5901 N NZ    . LYS B 2 403 ? 227.421 176.007 238.791 1.00 68.29  ? 406 LYS C NZ    1 
ATOM   5902 N N     . VAL B 2 404 ? 222.479 177.729 233.542 1.00 67.35  ? 407 VAL C N     1 
ATOM   5903 C CA    . VAL B 2 404 ? 222.187 179.123 233.227 1.00 67.35  ? 407 VAL C CA    1 
ATOM   5904 C C     . VAL B 2 404 ? 222.249 179.903 234.534 1.00 67.35  ? 407 VAL C C     1 
ATOM   5905 O O     . VAL B 2 404 ? 221.314 179.880 235.336 1.00 67.35  ? 407 VAL C O     1 
ATOM   5906 C CB    . VAL B 2 404 ? 220.829 179.274 232.535 1.00 67.35  ? 407 VAL C CB    1 
ATOM   5907 C CG1   . VAL B 2 404 ? 220.931 178.873 231.084 1.00 67.35  ? 407 VAL C CG1   1 
ATOM   5908 C CG2   . VAL B 2 404 ? 219.783 178.413 233.218 1.00 67.35  ? 407 VAL C CG2   1 
ATOM   5909 N N     . GLY B 2 405 ? 223.359 180.592 234.765 1.00 69.55  ? 408 GLY C N     1 
ATOM   5910 C CA    . GLY B 2 405 ? 223.466 181.375 235.976 1.00 69.55  ? 408 GLY C CA    1 
ATOM   5911 C C     . GLY B 2 405 ? 223.841 180.499 237.149 1.00 69.55  ? 408 GLY C C     1 
ATOM   5912 O O     . GLY B 2 405 ? 225.003 180.116 237.312 1.00 69.55  ? 408 GLY C O     1 
ATOM   5913 N N     . ASN B 2 406 ? 222.850 180.177 237.977 1.00 75.86  ? 409 ASN C N     1 
ATOM   5914 C CA    . ASN B 2 406 ? 223.024 179.237 239.070 1.00 75.86  ? 409 ASN C CA    1 
ATOM   5915 C C     . ASN B 2 406 ? 222.040 178.081 239.031 1.00 75.86  ? 409 ASN C C     1 
ATOM   5916 O O     . ASN B 2 406 ? 222.146 177.178 239.868 1.00 75.86  ? 409 ASN C O     1 
ATOM   5917 C CB    . ASN B 2 406 ? 222.899 179.953 240.422 1.00 75.86  ? 409 ASN C CB    1 
ATOM   5918 C CG    . ASN B 2 406 ? 224.134 180.754 240.770 1.00 75.86  ? 409 ASN C CG    1 
ATOM   5919 O OD1   . ASN B 2 406 ? 225.254 180.251 240.696 1.00 75.86  ? 409 ASN C OD1   1 
ATOM   5920 N ND2   . ASN B 2 406 ? 223.937 182.012 241.146 1.00 75.86  ? 409 ASN C ND2   1 
ATOM   5921 N N     . GLU B 2 407 ? 221.092 178.079 238.100 1.00 77.12  ? 410 GLU C N     1 
ATOM   5922 C CA    . GLU B 2 407 ? 220.121 177.008 237.947 1.00 77.12  ? 410 GLU C CA    1 
ATOM   5923 C C     . GLU B 2 407 ? 220.434 176.182 236.703 1.00 77.12  ? 410 GLU C C     1 
ATOM   5924 O O     . GLU B 2 407 ? 221.365 176.469 235.949 1.00 77.12  ? 410 GLU C O     1 
ATOM   5925 C CB    . GLU B 2 407 ? 218.707 177.587 237.866 1.00 77.12  ? 410 GLU C CB    1 
ATOM   5926 C CG    . GLU B 2 407 ? 217.632 176.711 238.473 1.00 77.12  ? 410 GLU C CG    1 
ATOM   5927 C CD    . GLU B 2 407 ? 216.253 177.315 238.327 1.00 77.12  ? 410 GLU C CD    1 
ATOM   5928 O OE1   . GLU B 2 407 ? 216.162 178.499 237.944 1.00 77.12  ? 410 GLU C OE1   1 
ATOM   5929 O OE2   . GLU B 2 407 ? 215.259 176.606 238.591 1.00 77.12  ? 410 GLU C OE2   1 
ATOM   5930 N N     . TYR B 2 408 ? 219.640 175.137 236.499 1.00 74.19  ? 411 TYR C N     1 
ATOM   5931 C CA    . TYR B 2 408 ? 219.772 174.254 235.353 1.00 74.19  ? 411 TYR C CA    1 
ATOM   5932 C C     . TYR B 2 408 ? 218.505 174.301 234.512 1.00 74.19  ? 411 TYR C C     1 
ATOM   5933 O O     . TYR B 2 408 ? 217.406 174.509 235.031 1.00 74.19  ? 411 TYR C O     1 
ATOM   5934 C CB    . TYR B 2 408 ? 220.045 172.812 235.793 1.00 74.19  ? 411 TYR C CB    1 
ATOM   5935 C CG    . TYR B 2 408 ? 221.478 172.548 236.193 1.00 74.19  ? 411 TYR C CG    1 
ATOM   5936 C CD1   . TYR B 2 408 ? 222.229 171.582 235.542 1.00 74.19  ? 411 TYR C CD1   1 
ATOM   5937 C CD2   . TYR B 2 408 ? 222.076 173.260 237.221 1.00 74.19  ? 411 TYR C CD2   1 
ATOM   5938 C CE1   . TYR B 2 408 ? 223.536 171.334 235.901 1.00 74.19  ? 411 TYR C CE1   1 
ATOM   5939 C CE2   . TYR B 2 408 ? 223.383 173.021 237.588 1.00 74.19  ? 411 TYR C CE2   1 
ATOM   5940 C CZ    . TYR B 2 408 ? 224.108 172.057 236.925 1.00 74.19  ? 411 TYR C CZ    1 
ATOM   5941 O OH    . TYR B 2 408 ? 225.412 171.813 237.285 1.00 74.19  ? 411 TYR C OH    1 
ATOM   5942 N N     . VAL B 2 409 ? 218.663 174.103 233.207 1.00 67.22  ? 412 VAL C N     1 
ATOM   5943 C CA    . VAL B 2 409 ? 217.536 174.092 232.284 1.00 67.22  ? 412 VAL C CA    1 
ATOM   5944 C C     . VAL B 2 409 ? 217.788 173.040 231.214 1.00 67.22  ? 412 VAL C C     1 
ATOM   5945 O O     . VAL B 2 409 ? 218.910 172.892 230.723 1.00 67.22  ? 412 VAL C O     1 
ATOM   5946 C CB    . VAL B 2 409 ? 217.301 175.484 231.656 1.00 67.22  ? 412 VAL C CB    1 
ATOM   5947 C CG1   . VAL B 2 409 ? 218.537 175.961 230.917 1.00 67.22  ? 412 VAL C CG1   1 
ATOM   5948 C CG2   . VAL B 2 409 ? 216.098 175.459 230.735 1.00 67.22  ? 412 VAL C CG2   1 
ATOM   5949 N N     . THR B 2 410 ? 216.743 172.294 230.869 1.00 65.82  ? 413 THR C N     1 
ATOM   5950 C CA    . THR B 2 410 ? 216.827 171.319 229.796 1.00 65.82  ? 413 THR C CA    1 
ATOM   5951 C C     . THR B 2 410 ? 216.989 172.048 228.460 1.00 65.82  ? 413 THR C C     1 
ATOM   5952 O O     . THR B 2 410 ? 216.892 173.273 228.373 1.00 65.82  ? 413 THR C O     1 
ATOM   5953 C CB    . THR B 2 410 ? 215.590 170.422 229.819 1.00 65.82  ? 413 THR C CB    1 
ATOM   5954 O OG1   . THR B 2 410 ? 215.343 169.998 231.163 1.00 65.82  ? 413 THR C OG1   1 
ATOM   5955 C CG2   . THR B 2 410 ? 215.793 169.179 228.979 1.00 65.82  ? 413 THR C CG2   1 
ATOM   5956 N N     . LYS B 2 411 ? 217.244 171.286 227.401 1.00 65.42  ? 414 LYS C N     1 
ATOM   5957 C CA    . LYS B 2 411 ? 217.472 171.855 226.085 1.00 65.42  ? 414 LYS C CA    1 
ATOM   5958 C C     . LYS B 2 411 ? 216.859 170.931 225.045 1.00 65.42  ? 414 LYS C C     1 
ATOM   5959 O O     . LYS B 2 411 ? 216.674 169.736 225.282 1.00 65.42  ? 414 LYS C O     1 
ATOM   5960 C CB    . LYS B 2 411 ? 218.967 172.055 225.821 1.00 65.42  ? 414 LYS C CB    1 
ATOM   5961 C CG    . LYS B 2 411 ? 219.299 173.325 225.077 1.00 65.42  ? 414 LYS C CG    1 
ATOM   5962 C CD    . LYS B 2 411 ? 220.792 173.475 224.886 1.00 65.42  ? 414 LYS C CD    1 
ATOM   5963 C CE    . LYS B 2 411 ? 221.116 174.753 224.131 1.00 65.42  ? 414 LYS C CE    1 
ATOM   5964 N NZ    . LYS B 2 411 ? 222.565 175.093 224.196 1.00 65.42  ? 414 LYS C NZ    1 
ATOM   5965 N N     . GLY B 2 412 ? 216.538 171.499 223.890 1.00 68.71  ? 415 GLY C N     1 
ATOM   5966 C CA    . GLY B 2 412 ? 215.935 170.753 222.806 1.00 68.71  ? 415 GLY C CA    1 
ATOM   5967 C C     . GLY B 2 412 ? 216.975 170.285 221.806 1.00 68.71  ? 415 GLY C C     1 
ATOM   5968 O O     . GLY B 2 412 ? 217.958 170.972 221.545 1.00 68.71  ? 415 GLY C O     1 
ATOM   5969 N N     . GLN B 2 413 ? 216.745 169.099 221.246 1.00 70.39  ? 416 GLN C N     1 
ATOM   5970 C CA    . GLN B 2 413 ? 217.681 168.485 220.312 1.00 70.39  ? 416 GLN C CA    1 
ATOM   5971 C C     . GLN B 2 413 ? 216.906 167.788 219.209 1.00 70.39  ? 416 GLN C C     1 
ATOM   5972 O O     . GLN B 2 413 ? 216.156 166.847 219.478 1.00 70.39  ? 416 GLN C O     1 
ATOM   5973 C CB    . GLN B 2 413 ? 218.595 167.483 221.020 1.00 70.39  ? 416 GLN C CB    1 
ATOM   5974 C CG    . GLN B 2 413 ? 219.443 168.074 222.116 1.00 70.39  ? 416 GLN C CG    1 
ATOM   5975 C CD    . GLN B 2 413 ? 220.756 168.611 221.610 1.00 70.39  ? 416 GLN C CD    1 
ATOM   5976 O OE1   . GLN B 2 413 ? 221.658 167.851 221.267 1.00 70.39  ? 416 GLN C OE1   1 
ATOM   5977 N NE2   . GLN B 2 413 ? 220.874 169.929 221.561 1.00 70.39  ? 416 GLN C NE2   1 
ATOM   5978 N N     . SER B 2 414 ? 217.091 168.241 217.975 1.00 71.74  ? 417 SER C N     1 
ATOM   5979 C CA    . SER B 2 414 ? 216.555 167.525 216.832 1.00 71.74  ? 417 SER C CA    1 
ATOM   5980 C C     . SER B 2 414 ? 217.378 166.267 216.569 1.00 71.74  ? 417 SER C C     1 
ATOM   5981 O O     . SER B 2 414 ? 218.405 166.019 217.204 1.00 71.74  ? 417 SER C O     1 
ATOM   5982 C CB    . SER B 2 414 ? 216.533 168.425 215.601 1.00 71.74  ? 417 SER C CB    1 
ATOM   5983 O OG    . SER B 2 414 ? 217.733 169.168 215.493 1.00 71.74  ? 417 SER C OG    1 
ATOM   5984 N N     . VAL B 2 415 ? 216.914 165.460 215.615 1.00 71.99  ? 418 VAL C N     1 
ATOM   5985 C CA    . VAL B 2 415 ? 217.599 164.205 215.314 1.00 71.99  ? 418 VAL C CA    1 
ATOM   5986 C C     . VAL B 2 415 ? 219.011 164.472 214.806 1.00 71.99  ? 418 VAL C C     1 
ATOM   5987 O O     . VAL B 2 415 ? 219.960 163.761 215.161 1.00 71.99  ? 418 VAL C O     1 
ATOM   5988 C CB    . VAL B 2 415 ? 216.778 163.377 214.310 1.00 71.99  ? 418 VAL C CB    1 
ATOM   5989 C CG1   . VAL B 2 415 ? 217.622 162.260 213.723 1.00 71.99  ? 418 VAL C CG1   1 
ATOM   5990 C CG2   . VAL B 2 415 ? 215.548 162.812 214.985 1.00 71.99  ? 418 VAL C CG2   1 
ATOM   5991 N N     . GLN B 2 416 ? 219.177 165.506 213.979 1.00 70.48  ? 419 GLN C N     1 
ATOM   5992 C CA    . GLN B 2 416 ? 220.505 165.828 213.468 1.00 70.48  ? 419 GLN C CA    1 
ATOM   5993 C C     . GLN B 2 416 ? 221.452 166.201 214.599 1.00 70.48  ? 419 GLN C C     1 
ATOM   5994 O O     . GLN B 2 416 ? 222.619 165.793 214.603 1.00 70.48  ? 419 GLN C O     1 
ATOM   5995 C CB    . GLN B 2 416 ? 220.418 166.964 212.450 1.00 70.48  ? 419 GLN C CB    1 
ATOM   5996 C CG    . GLN B 2 416 ? 219.549 166.665 211.243 1.00 70.48  ? 419 GLN C CG    1 
ATOM   5997 C CD    . GLN B 2 416 ? 219.993 165.434 210.478 1.00 70.48  ? 419 GLN C CD    1 
ATOM   5998 O OE1   . GLN B 2 416 ? 221.170 165.074 210.478 1.00 70.48  ? 419 GLN C OE1   1 
ATOM   5999 N NE2   . GLN B 2 416 ? 219.046 164.778 209.820 1.00 70.48  ? 419 GLN C NE2   1 
ATOM   6000 N N     . GLN B 2 417 ? 220.964 166.968 215.574 1.00 67.72  ? 420 GLN C N     1 
ATOM   6001 C CA    . GLN B 2 417 ? 221.813 167.363 216.690 1.00 67.72  ? 420 GLN C CA    1 
ATOM   6002 C C     . GLN B 2 417 ? 222.170 166.167 217.561 1.00 67.72  ? 420 GLN C C     1 
ATOM   6003 O O     . GLN B 2 417 ? 223.291 166.075 218.072 1.00 67.72  ? 420 GLN C O     1 
ATOM   6004 C CB    . GLN B 2 417 ? 221.120 168.448 217.508 1.00 67.72  ? 420 GLN C CB    1 
ATOM   6005 C CG    . GLN B 2 417 ? 221.000 169.772 216.779 1.00 67.72  ? 420 GLN C CG    1 
ATOM   6006 C CD    . GLN B 2 417 ? 220.033 170.719 217.450 1.00 67.72  ? 420 GLN C CD    1 
ATOM   6007 O OE1   . GLN B 2 417 ? 218.894 170.359 217.731 1.00 67.72  ? 420 GLN C OE1   1 
ATOM   6008 N NE2   . GLN B 2 417 ? 220.481 171.939 217.708 1.00 67.72  ? 420 GLN C NE2   1 
ATOM   6009 N N     . VAL B 2 418 ? 221.238 165.227 217.726 1.00 65.41  ? 421 VAL C N     1 
ATOM   6010 C CA    . VAL B 2 418 ? 221.534 164.025 218.498 1.00 65.41  ? 421 VAL C CA    1 
ATOM   6011 C C     . VAL B 2 418 ? 222.583 163.178 217.788 1.00 65.41  ? 421 VAL C C     1 
ATOM   6012 O O     . VAL B 2 418 ? 223.479 162.612 218.426 1.00 65.41  ? 421 VAL C O     1 
ATOM   6013 C CB    . VAL B 2 418 ? 220.242 163.235 218.769 1.00 65.41  ? 421 VAL C CB    1 
ATOM   6014 C CG1   . VAL B 2 418 ? 220.553 161.794 219.107 1.00 65.41  ? 421 VAL C CG1   1 
ATOM   6015 C CG2   . VAL B 2 418 ? 219.467 163.880 219.895 1.00 65.41  ? 421 VAL C CG2   1 
ATOM   6016 N N     . TYR B 2 419 ? 222.506 163.089 216.458 1.00 67.05  ? 422 TYR C N     1 
ATOM   6017 C CA    . TYR B 2 419 ? 223.525 162.347 215.721 1.00 67.05  ? 422 TYR C CA    1 
ATOM   6018 C C     . TYR B 2 419 ? 224.886 163.027 215.808 1.00 67.05  ? 422 TYR C C     1 
ATOM   6019 O O     . TYR B 2 419 ? 225.915 162.353 215.950 1.00 67.05  ? 422 TYR C O     1 
ATOM   6020 C CB    . TYR B 2 419 ? 223.101 162.173 214.266 1.00 67.05  ? 422 TYR C CB    1 
ATOM   6021 C CG    . TYR B 2 419 ? 222.059 161.101 214.060 1.00 67.05  ? 422 TYR C CG    1 
ATOM   6022 C CD1   . TYR B 2 419 ? 221.826 160.142 215.030 1.00 67.05  ? 422 TYR C CD1   1 
ATOM   6023 C CD2   . TYR B 2 419 ? 221.316 161.044 212.892 1.00 67.05  ? 422 TYR C CD2   1 
ATOM   6024 C CE1   . TYR B 2 419 ? 220.885 159.158 214.844 1.00 67.05  ? 422 TYR C CE1   1 
ATOM   6025 C CE2   . TYR B 2 419 ? 220.373 160.064 212.699 1.00 67.05  ? 422 TYR C CE2   1 
ATOM   6026 C CZ    . TYR B 2 419 ? 220.161 159.124 213.677 1.00 67.05  ? 422 TYR C CZ    1 
ATOM   6027 O OH    . TYR B 2 419 ? 219.217 158.144 213.487 1.00 67.05  ? 422 TYR C OH    1 
ATOM   6028 N N     . TYR B 2 420 ? 224.913 164.358 215.725 1.00 64.00  ? 423 TYR C N     1 
ATOM   6029 C CA    . TYR B 2 420 ? 226.162 165.081 215.935 1.00 64.00  ? 423 TYR C CA    1 
ATOM   6030 C C     . TYR B 2 420 ? 226.737 164.791 217.314 1.00 64.00  ? 423 TYR C C     1 
ATOM   6031 O O     . TYR B 2 420 ? 227.951 164.609 217.465 1.00 64.00  ? 423 TYR C O     1 
ATOM   6032 C CB    . TYR B 2 420 ? 225.941 166.582 215.766 1.00 64.00  ? 423 TYR C CB    1 
ATOM   6033 C CG    . TYR B 2 420 ? 225.680 167.016 214.348 1.00 64.00  ? 423 TYR C CG    1 
ATOM   6034 C CD1   . TYR B 2 420 ? 226.030 166.208 213.279 1.00 64.00  ? 423 TYR C CD1   1 
ATOM   6035 C CD2   . TYR B 2 420 ? 225.083 168.236 214.079 1.00 64.00  ? 423 TYR C CD2   1 
ATOM   6036 C CE1   . TYR B 2 420 ? 225.791 166.602 211.983 1.00 64.00  ? 423 TYR C CE1   1 
ATOM   6037 C CE2   . TYR B 2 420 ? 224.841 168.638 212.787 1.00 64.00  ? 423 TYR C CE2   1 
ATOM   6038 C CZ    . TYR B 2 420 ? 225.197 167.818 211.743 1.00 64.00  ? 423 TYR C CZ    1 
ATOM   6039 O OH    . TYR B 2 420 ? 224.958 168.217 210.449 1.00 64.00  ? 423 TYR C OH    1 
ATOM   6040 N N     . SER B 2 421 ? 225.877 164.741 218.333 1.00 62.32  ? 424 SER C N     1 
ATOM   6041 C CA    . SER B 2 421 ? 226.356 164.485 219.687 1.00 62.32  ? 424 SER C CA    1 
ATOM   6042 C C     . SER B 2 421 ? 226.916 163.077 219.818 1.00 62.32  ? 424 SER C C     1 
ATOM   6043 O O     . SER B 2 421 ? 227.955 162.878 220.453 1.00 62.32  ? 424 SER C O     1 
ATOM   6044 C CB    . SER B 2 421 ? 225.235 164.711 220.696 1.00 62.32  ? 424 SER C CB    1 
ATOM   6045 O OG    . SER B 2 421 ? 225.012 166.093 220.906 1.00 62.32  ? 424 SER C OG    1 
ATOM   6046 N N     . ILE B 2 422 ? 226.249 162.088 219.220 1.00 61.29  ? 425 ILE C N     1 
ATOM   6047 C CA    . ILE B 2 422 ? 226.753 160.718 219.284 1.00 61.29  ? 425 ILE C CA    1 
ATOM   6048 C C     . ILE B 2 422 ? 228.105 160.616 218.592 1.00 61.29  ? 425 ILE C C     1 
ATOM   6049 O O     . ILE B 2 422 ? 229.038 159.978 219.102 1.00 61.29  ? 425 ILE C O     1 
ATOM   6050 C CB    . ILE B 2 422 ? 225.735 159.738 218.677 1.00 61.29  ? 425 ILE C CB    1 
ATOM   6051 C CG1   . ILE B 2 422 ? 224.451 159.724 219.499 1.00 61.29  ? 425 ILE C CG1   1 
ATOM   6052 C CG2   . ILE B 2 422 ? 226.323 158.344 218.602 1.00 61.29  ? 425 ILE C CG2   1 
ATOM   6053 C CD1   . ILE B 2 422 ? 223.455 158.689 219.045 1.00 61.29  ? 425 ILE C CD1   1 
ATOM   6054 N N     . GLY B 2 423 ? 228.238 161.245 217.424 1.00 60.55  ? 426 GLY C N     1 
ATOM   6055 C CA    . GLY B 2 423 ? 229.518 161.231 216.738 1.00 60.55  ? 426 GLY C CA    1 
ATOM   6056 C C     . GLY B 2 423 ? 230.627 161.881 217.544 1.00 60.55  ? 426 GLY C C     1 
ATOM   6057 O O     . GLY B 2 423 ? 231.731 161.337 217.655 1.00 60.55  ? 426 GLY C O     1 
ATOM   6058 N N     . ALA B 2 424 ? 230.349 163.053 218.118 1.00 60.64  ? 427 ALA C N     1 
ATOM   6059 C CA    . ALA B 2 424 ? 231.361 163.743 218.909 1.00 60.64  ? 427 ALA C CA    1 
ATOM   6060 C C     . ALA B 2 424 ? 231.742 162.938 220.143 1.00 60.64  ? 427 ALA C C     1 
ATOM   6061 O O     . ALA B 2 424 ? 232.915 162.907 220.535 1.00 60.64  ? 427 ALA C O     1 
ATOM   6062 C CB    . ALA B 2 424 ? 230.858 165.128 219.307 1.00 60.64  ? 427 ALA C CB    1 
ATOM   6063 N N     . LEU B 2 425 ? 230.769 162.266 220.761 1.00 61.58  ? 428 LEU C N     1 
ATOM   6064 C CA    . LEU B 2 425 ? 231.069 161.433 221.920 1.00 61.58  ? 428 LEU C CA    1 
ATOM   6065 C C     . LEU B 2 425 ? 231.964 160.264 221.541 1.00 61.58  ? 428 LEU C C     1 
ATOM   6066 O O     . LEU B 2 425 ? 232.922 159.951 222.260 1.00 61.58  ? 428 LEU C O     1 
ATOM   6067 C CB    . LEU B 2 425 ? 229.775 160.930 222.548 1.00 61.58  ? 428 LEU C CB    1 
ATOM   6068 C CG    . LEU B 2 425 ? 229.017 161.960 223.373 1.00 61.58  ? 428 LEU C CG    1 
ATOM   6069 C CD1   . LEU B 2 425 ? 227.692 161.386 223.812 1.00 61.58  ? 428 LEU C CD1   1 
ATOM   6070 C CD2   . LEU B 2 425 ? 229.843 162.386 224.568 1.00 61.58  ? 428 LEU C CD2   1 
ATOM   6071 N N     . ALA B 2 426 ? 231.664 159.600 220.423 1.00 60.34  ? 429 ALA C N     1 
ATOM   6072 C CA    . ALA B 2 426 ? 232.507 158.495 219.978 1.00 60.34  ? 429 ALA C CA    1 
ATOM   6073 C C     . ALA B 2 426 ? 233.930 158.969 219.711 1.00 60.34  ? 429 ALA C C     1 
ATOM   6074 O O     . ALA B 2 426 ? 234.903 158.326 220.128 1.00 60.34  ? 429 ALA C O     1 
ATOM   6075 C CB    . ALA B 2 426 ? 231.910 157.851 218.730 1.00 60.34  ? 429 ALA C CB    1 
ATOM   6076 N N     . LYS B 2 427 ? 234.070 160.107 219.028 1.00 59.68  ? 430 LYS C N     1 
ATOM   6077 C CA    . LYS B 2 427 ? 235.403 160.624 218.734 1.00 59.68  ? 430 LYS C CA    1 
ATOM   6078 C C     . LYS B 2 427 ? 236.162 160.956 220.010 1.00 59.68  ? 430 LYS C C     1 
ATOM   6079 O O     . LYS B 2 427 ? 237.355 160.644 220.131 1.00 59.68  ? 430 LYS C O     1 
ATOM   6080 C CB    . LYS B 2 427 ? 235.307 161.856 217.841 1.00 59.68  ? 430 LYS C CB    1 
ATOM   6081 C CG    . LYS B 2 427 ? 234.904 161.552 216.420 1.00 59.68  ? 430 LYS C CG    1 
ATOM   6082 C CD    . LYS B 2 427 ? 235.119 162.756 215.531 1.00 59.68  ? 430 LYS C CD    1 
ATOM   6083 C CE    . LYS B 2 427 ? 234.192 163.888 215.910 1.00 59.68  ? 430 LYS C CE    1 
ATOM   6084 N NZ    . LYS B 2 427 ? 234.293 165.019 214.957 1.00 59.68  ? 430 LYS C NZ    1 
ATOM   6085 N N     . SER B 2 428 ? 235.491 161.590 220.975 1.00 62.05  ? 431 SER C N     1 
ATOM   6086 C CA    . SER B 2 428 ? 236.168 161.967 222.211 1.00 62.05  ? 431 SER C CA    1 
ATOM   6087 C C     . SER B 2 428 ? 236.605 160.740 222.995 1.00 62.05  ? 431 SER C C     1 
ATOM   6088 O O     . SER B 2 428 ? 237.730 160.694 223.504 1.00 62.05  ? 431 SER C O     1 
ATOM   6089 C CB    . SER B 2 428 ? 235.260 162.852 223.060 1.00 62.05  ? 431 SER C CB    1 
ATOM   6090 O OG    . SER B 2 428 ? 234.924 164.040 222.370 1.00 62.05  ? 431 SER C OG    1 
ATOM   6091 N N     . VAL B 2 429 ? 235.734 159.734 223.098 1.00 61.30  ? 432 VAL C N     1 
ATOM   6092 C CA    . VAL B 2 429 ? 236.108 158.509 223.797 1.00 61.30  ? 432 VAL C CA    1 
ATOM   6093 C C     . VAL B 2 429 ? 237.319 157.868 223.134 1.00 61.30  ? 432 VAL C C     1 
ATOM   6094 O O     . VAL B 2 429 ? 238.271 157.458 223.813 1.00 61.30  ? 432 VAL C O     1 
ATOM   6095 C CB    . VAL B 2 429 ? 234.914 157.540 223.857 1.00 61.30  ? 432 VAL C CB    1 
ATOM   6096 C CG1   . VAL B 2 429 ? 235.389 156.123 224.101 1.00 61.30  ? 432 VAL C CG1   1 
ATOM   6097 C CG2   . VAL B 2 429 ? 233.953 157.967 224.938 1.00 61.30  ? 432 VAL C CG2   1 
ATOM   6098 N N     . TYR B 2 430 ? 237.315 157.788 221.800 1.00 63.45  ? 433 TYR C N     1 
ATOM   6099 C CA    . TYR B 2 430 ? 238.422 157.132 221.112 1.00 63.45  ? 433 TYR C CA    1 
ATOM   6100 C C     . TYR B 2 430 ? 239.733 157.881 221.319 1.00 63.45  ? 433 TYR C C     1 
ATOM   6101 O O     . TYR B 2 430 ? 240.771 157.266 221.593 1.00 63.45  ? 433 TYR C O     1 
ATOM   6102 C CB    . TYR B 2 430 ? 238.118 156.994 219.623 1.00 63.45  ? 433 TYR C CB    1 
ATOM   6103 C CG    . TYR B 2 430 ? 239.158 156.193 218.882 1.00 63.45  ? 433 TYR C CG    1 
ATOM   6104 C CD1   . TYR B 2 430 ? 240.217 156.816 218.248 1.00 63.45  ? 433 TYR C CD1   1 
ATOM   6105 C CD2   . TYR B 2 430 ? 239.086 154.811 218.831 1.00 63.45  ? 433 TYR C CD2   1 
ATOM   6106 C CE1   . TYR B 2 430 ? 241.168 156.091 217.580 1.00 63.45  ? 433 TYR C CE1   1 
ATOM   6107 C CE2   . TYR B 2 430 ? 240.035 154.078 218.163 1.00 63.45  ? 433 TYR C CE2   1 
ATOM   6108 C CZ    . TYR B 2 430 ? 241.073 154.724 217.541 1.00 63.45  ? 433 TYR C CZ    1 
ATOM   6109 O OH    . TYR B 2 430 ? 242.029 154.001 216.873 1.00 63.45  ? 433 TYR C OH    1 
ATOM   6110 N N     . GLU B 2 431 ? 239.709 159.210 221.207 1.00 63.83  ? 434 GLU C N     1 
ATOM   6111 C CA    . GLU B 2 431 ? 240.956 159.954 221.350 1.00 63.83  ? 434 GLU C CA    1 
ATOM   6112 C C     . GLU B 2 431 ? 241.463 159.922 222.785 1.00 63.83  ? 434 GLU C C     1 
ATOM   6113 O O     . GLU B 2 431 ? 242.677 159.879 223.018 1.00 63.83  ? 434 GLU C O     1 
ATOM   6114 C CB    . GLU B 2 431 ? 240.786 161.395 220.886 1.00 63.83  ? 434 GLU C CB    1 
ATOM   6115 C CG    . GLU B 2 431 ? 242.115 162.103 220.713 1.00 63.83  ? 434 GLU C CG    1 
ATOM   6116 C CD    . GLU B 2 431 ? 241.989 163.606 220.746 1.00 63.83  ? 434 GLU C CD    1 
ATOM   6117 O OE1   . GLU B 2 431 ? 240.846 164.106 220.785 1.00 63.83  ? 434 GLU C OE1   1 
ATOM   6118 O OE2   . GLU B 2 431 ? 243.036 164.289 220.739 1.00 63.83  ? 434 GLU C OE2   1 
ATOM   6119 N N     . LYS B 2 432 ? 240.558 159.930 223.766 1.00 62.95  ? 435 LYS C N     1 
ATOM   6120 C CA    . LYS B 2 432 ? 241.009 159.851 225.149 1.00 62.95  ? 435 LYS C CA    1 
ATOM   6121 C C     . LYS B 2 432 ? 241.606 158.485 225.456 1.00 62.95  ? 435 LYS C C     1 
ATOM   6122 O O     . LYS B 2 432 ? 242.608 158.389 226.174 1.00 62.95  ? 435 LYS C O     1 
ATOM   6123 C CB    . LYS B 2 432 ? 239.859 160.175 226.099 1.00 62.95  ? 435 LYS C CB    1 
ATOM   6124 C CG    . LYS B 2 432 ? 239.395 161.611 225.997 1.00 62.95  ? 435 LYS C CG    1 
ATOM   6125 C CD    . LYS B 2 432 ? 238.752 162.091 227.275 1.00 62.95  ? 435 LYS C CD    1 
ATOM   6126 C CE    . LYS B 2 432 ? 238.350 163.545 227.150 1.00 62.95  ? 435 LYS C CE    1 
ATOM   6127 N NZ    . LYS B 2 432 ? 238.167 164.187 228.477 1.00 62.95  ? 435 LYS C NZ    1 
ATOM   6128 N N     . MET B 2 433 ? 241.027 157.417 224.903 1.00 65.43  ? 436 MET C N     1 
ATOM   6129 C CA    . MET B 2 433 ? 241.626 156.098 225.078 1.00 65.43  ? 436 MET C CA    1 
ATOM   6130 C C     . MET B 2 433 ? 242.993 156.023 224.410 1.00 65.43  ? 436 MET C C     1 
ATOM   6131 O O     . MET B 2 433 ? 243.927 155.414 224.947 1.00 65.43  ? 436 MET C O     1 
ATOM   6132 C CB    . MET B 2 433 ? 240.700 155.022 224.524 1.00 65.43  ? 436 MET C CB    1 
ATOM   6133 C CG    . MET B 2 433 ? 241.255 153.622 224.634 1.00 65.43  ? 436 MET C CG    1 
ATOM   6134 S SD    . MET B 2 433 ? 239.983 152.375 224.382 1.00 65.43  ? 436 MET C SD    1 
ATOM   6135 C CE    . MET B 2 433 ? 239.357 152.849 222.774 1.00 65.43  ? 436 MET C CE    1 
ATOM   6136 N N     . PHE B 2 434 ? 243.135 156.651 223.243 1.00 64.16  ? 437 PHE C N     1 
ATOM   6137 C CA    . PHE B 2 434 ? 244.427 156.669 222.566 1.00 64.16  ? 437 PHE C CA    1 
ATOM   6138 C C     . PHE B 2 434 ? 245.478 157.392 223.403 1.00 64.16  ? 437 PHE C C     1 
ATOM   6139 O O     . PHE B 2 434 ? 246.615 156.920 223.544 1.00 64.16  ? 437 PHE C O     1 
ATOM   6140 C CB    . PHE B 2 434 ? 244.277 157.324 221.196 1.00 64.16  ? 437 PHE C CB    1 
ATOM   6141 C CG    . PHE B 2 434 ? 245.523 157.300 220.373 1.00 64.16  ? 437 PHE C CG    1 
ATOM   6142 C CD1   . PHE B 2 434 ? 246.331 158.417 220.287 1.00 64.16  ? 437 PHE C CD1   1 
ATOM   6143 C CD2   . PHE B 2 434 ? 245.886 156.164 219.680 1.00 64.16  ? 437 PHE C CD2   1 
ATOM   6144 C CE1   . PHE B 2 434 ? 247.475 158.397 219.530 1.00 64.16  ? 437 PHE C CE1   1 
ATOM   6145 C CE2   . PHE B 2 434 ? 247.031 156.141 218.921 1.00 64.16  ? 437 PHE C CE2   1 
ATOM   6146 C CZ    . PHE B 2 434 ? 247.826 157.259 218.846 1.00 64.16  ? 437 PHE C CZ    1 
ATOM   6147 N N     . ASN B 2 435 ? 245.116 158.545 223.966 1.00 63.80  ? 438 ASN C N     1 
ATOM   6148 C CA    . ASN B 2 435 ? 246.064 159.280 224.796 1.00 63.80  ? 438 ASN C CA    1 
ATOM   6149 C C     . ASN B 2 435 ? 246.409 158.508 226.063 1.00 63.80  ? 438 ASN C C     1 
ATOM   6150 O O     . ASN B 2 435 ? 247.554 158.544 226.523 1.00 63.80  ? 438 ASN C O     1 
ATOM   6151 C CB    . ASN B 2 435 ? 245.505 160.658 225.140 1.00 63.80  ? 438 ASN C CB    1 
ATOM   6152 C CG    . ASN B 2 435 ? 245.675 161.649 224.013 1.00 63.80  ? 438 ASN C CG    1 
ATOM   6153 O OD1   . ASN B 2 435 ? 246.587 161.528 223.200 1.00 63.80  ? 438 ASN C OD1   1 
ATOM   6154 N ND2   . ASN B 2 435 ? 244.796 162.639 223.959 1.00 63.80  ? 438 ASN C ND2   1 
ATOM   6155 N N     . TRP B 2 436 ? 245.436 157.799 226.639 1.00 66.68  ? 439 TRP C N     1 
ATOM   6156 C CA    . TRP B 2 436 ? 245.726 156.959 227.797 1.00 66.68  ? 439 TRP C CA    1 
ATOM   6157 C C     . TRP B 2 436 ? 246.711 155.853 227.444 1.00 66.68  ? 439 TRP C C     1 
ATOM   6158 O O     . TRP B 2 436 ? 247.610 155.532 228.232 1.00 66.68  ? 439 TRP C O     1 
ATOM   6159 C CB    . TRP B 2 436 ? 244.430 156.367 228.344 1.00 66.68  ? 439 TRP C CB    1 
ATOM   6160 C CG    . TRP B 2 436 ? 244.625 155.330 229.395 1.00 66.68  ? 439 TRP C CG    1 
ATOM   6161 C CD1   . TRP B 2 436 ? 244.831 155.541 230.723 1.00 66.68  ? 439 TRP C CD1   1 
ATOM   6162 C CD2   . TRP B 2 436 ? 244.620 153.913 229.209 1.00 66.68  ? 439 TRP C CD2   1 
ATOM   6163 N NE1   . TRP B 2 436 ? 244.958 154.343 231.377 1.00 66.68  ? 439 TRP C NE1   1 
ATOM   6164 C CE2   . TRP B 2 436 ? 244.833 153.327 230.468 1.00 66.68  ? 439 TRP C CE2   1 
ATOM   6165 C CE3   . TRP B 2 436 ? 244.459 153.083 228.100 1.00 66.68  ? 439 TRP C CE3   1 
ATOM   6166 C CZ2   . TRP B 2 436 ? 244.888 151.953 230.649 1.00 66.68  ? 439 TRP C CZ2   1 
ATOM   6167 C CZ3   . TRP B 2 436 ? 244.515 151.720 228.281 1.00 66.68  ? 439 TRP C CZ3   1 
ATOM   6168 C CH2   . TRP B 2 436 ? 244.728 151.168 229.545 1.00 66.68  ? 439 TRP C CH2   1 
ATOM   6169 N N     . MET B 2 437 ? 246.556 155.256 226.262 1.00 71.22  ? 440 MET C N     1 
ATOM   6170 C CA    . MET B 2 437 ? 247.492 154.222 225.836 1.00 71.22  ? 440 MET C CA    1 
ATOM   6171 C C     . MET B 2 437 ? 248.895 154.790 225.659 1.00 71.22  ? 440 MET C C     1 
ATOM   6172 O O     . MET B 2 437 ? 249.885 154.165 226.065 1.00 71.22  ? 440 MET C O     1 
ATOM   6173 C CB    . MET B 2 437 ? 247.003 153.588 224.539 1.00 71.22  ? 440 MET C CB    1 
ATOM   6174 C CG    . MET B 2 437 ? 247.583 152.228 224.255 1.00 71.22  ? 440 MET C CG    1 
ATOM   6175 S SD    . MET B 2 437 ? 246.584 151.353 223.043 1.00 71.22  ? 440 MET C SD    1 
ATOM   6176 C CE    . MET B 2 437 ? 244.954 151.562 223.749 1.00 71.22  ? 440 MET C CE    1 
ATOM   6177 N N     . VAL B 2 438 ? 248.998 155.974 225.056 1.00 68.80  ? 441 VAL C N     1 
ATOM   6178 C CA    . VAL B 2 438 ? 250.302 156.617 224.914 1.00 68.80  ? 441 VAL C CA    1 
ATOM   6179 C C     . VAL B 2 438 ? 250.902 156.911 226.283 1.00 68.80  ? 441 VAL C C     1 
ATOM   6180 O O     . VAL B 2 438 ? 252.116 156.791 226.484 1.00 68.80  ? 441 VAL C O     1 
ATOM   6181 C CB    . VAL B 2 438 ? 250.181 157.893 224.063 1.00 68.80  ? 441 VAL C CB    1 
ATOM   6182 C CG1   . VAL B 2 438 ? 251.490 158.648 224.053 1.00 68.80  ? 441 VAL C CG1   1 
ATOM   6183 C CG2   . VAL B 2 438 ? 249.767 157.541 222.655 1.00 68.80  ? 441 VAL C CG2   1 
ATOM   6184 N N     . THR B 2 439 ? 250.061 157.286 227.248 1.00 70.34  ? 442 THR C N     1 
ATOM   6185 C CA    . THR B 2 439 ? 250.553 157.561 228.595 1.00 70.34  ? 442 THR C CA    1 
ATOM   6186 C C     . THR B 2 439 ? 251.100 156.300 229.251 1.00 70.34  ? 442 THR C C     1 
ATOM   6187 O O     . THR B 2 439 ? 252.154 156.332 229.896 1.00 70.34  ? 442 THR C O     1 
ATOM   6188 C CB    . THR B 2 439 ? 249.437 158.166 229.445 1.00 70.34  ? 442 THR C CB    1 
ATOM   6189 O OG1   . THR B 2 439 ? 249.015 159.406 228.866 1.00 70.34  ? 442 THR C OG1   1 
ATOM   6190 C CG2   . THR B 2 439 ? 249.913 158.417 230.860 1.00 70.34  ? 442 THR C CG2   1 
ATOM   6191 N N     . ARG B 2 440 ? 250.401 155.179 229.093 1.00 73.85  ? 443 ARG C N     1 
ATOM   6192 C CA    . ARG B 2 440 ? 250.887 153.937 229.684 1.00 73.85  ? 443 ARG C CA    1 
ATOM   6193 C C     . ARG B 2 440 ? 252.174 153.468 229.013 1.00 73.85  ? 443 ARG C C     1 
ATOM   6194 O O     . ARG B 2 440 ? 253.047 152.885 229.668 1.00 73.85  ? 443 ARG C O     1 
ATOM   6195 C CB    . ARG B 2 440 ? 249.809 152.863 229.609 1.00 73.85  ? 443 ARG C CB    1 
ATOM   6196 C CG    . ARG B 2 440 ? 248.674 153.109 230.575 1.00 73.85  ? 443 ARG C CG    1 
ATOM   6197 C CD    . ARG B 2 440 ? 248.966 152.495 231.929 1.00 73.85  ? 443 ARG C CD    1 
ATOM   6198 N NE    . ARG B 2 440 ? 248.954 151.039 231.869 1.00 73.85  ? 443 ARG C NE    1 
ATOM   6199 C CZ    . ARG B 2 440 ? 248.966 150.249 232.936 1.00 73.85  ? 443 ARG C CZ    1 
ATOM   6200 N NH1   . ARG B 2 440 ? 248.994 150.773 234.151 1.00 73.85  ? 443 ARG C NH1   1 
ATOM   6201 N NH2   . ARG B 2 440 ? 248.948 148.935 232.787 1.00 73.85  ? 443 ARG C NH2   1 
ATOM   6202 N N     . ILE B 2 441 ? 252.319 153.725 227.712 1.00 73.20  ? 444 ILE C N     1 
ATOM   6203 C CA    . ILE B 2 441 ? 253.575 153.402 227.036 1.00 73.20  ? 444 ILE C CA    1 
ATOM   6204 C C     . ILE B 2 441 ? 254.709 154.267 227.580 1.00 73.20  ? 444 ILE C C     1 
ATOM   6205 O O     . ILE B 2 441 ? 255.796 153.772 227.902 1.00 73.20  ? 444 ILE C O     1 
ATOM   6206 C CB    . ILE B 2 441 ? 253.421 153.554 225.514 1.00 73.20  ? 444 ILE C CB    1 
ATOM   6207 C CG1   . ILE B 2 441 ? 252.590 152.398 224.954 1.00 73.20  ? 444 ILE C CG1   1 
ATOM   6208 C CG2   . ILE B 2 441 ? 254.776 153.598 224.844 1.00 73.20  ? 444 ILE C CG2   1 
ATOM   6209 C CD1   . ILE B 2 441 ? 252.147 152.599 223.527 1.00 73.20  ? 444 ILE C CD1   1 
ATOM   6210 N N     . ASN B 2 442 ? 254.471 155.575 227.690 1.00 73.40  ? 445 ASN C N     1 
ATOM   6211 C CA    . ASN B 2 442 ? 255.457 156.458 228.302 1.00 73.40  ? 445 ASN C CA    1 
ATOM   6212 C C     . ASN B 2 442 ? 255.816 156.011 229.711 1.00 73.40  ? 445 ASN C C     1 
ATOM   6213 O O     . ASN B 2 442 ? 256.959 156.187 230.143 1.00 73.40  ? 445 ASN C O     1 
ATOM   6214 C CB    . ASN B 2 442 ? 254.936 157.892 228.327 1.00 73.40  ? 445 ASN C CB    1 
ATOM   6215 C CG    . ASN B 2 442 ? 254.922 158.520 226.962 1.00 73.40  ? 445 ASN C CG    1 
ATOM   6216 O OD1   . ASN B 2 442 ? 255.747 158.189 226.115 1.00 73.40  ? 445 ASN C OD1   1 
ATOM   6217 N ND2   . ASN B 2 442 ? 253.980 159.426 226.731 1.00 73.40  ? 445 ASN C ND2   1 
ATOM   6218 N N     . ALA B 2 443 ? 254.859 155.438 230.440 1.00 77.40  ? 446 ALA C N     1 
ATOM   6219 C CA    . ALA B 2 443 ? 255.141 154.976 231.795 1.00 77.40  ? 446 ALA C CA    1 
ATOM   6220 C C     . ALA B 2 443 ? 256.034 153.743 231.781 1.00 77.40  ? 446 ALA C C     1 
ATOM   6221 O O     . ALA B 2 443 ? 257.023 153.673 232.518 1.00 77.40  ? 446 ALA C O     1 
ATOM   6222 C CB    . ALA B 2 443 ? 253.839 154.686 232.537 1.00 77.40  ? 446 ALA C CB    1 
ATOM   6223 N N     . THR B 2 444 ? 255.696 152.751 230.958 1.00 78.77  ? 447 THR C N     1 
ATOM   6224 C CA    . THR B 2 444 ? 256.522 151.550 230.905 1.00 78.77  ? 447 THR C CA    1 
ATOM   6225 C C     . THR B 2 444 ? 257.887 151.795 230.270 1.00 78.77  ? 447 THR C C     1 
ATOM   6226 O O     . THR B 2 444 ? 258.768 150.940 230.400 1.00 78.77  ? 447 THR C O     1 
ATOM   6227 C CB    . THR B 2 444 ? 255.804 150.428 230.158 1.00 78.77  ? 447 THR C CB    1 
ATOM   6228 O OG1   . THR B 2 444 ? 256.665 149.287 230.071 1.00 78.77  ? 447 THR C OG1   1 
ATOM   6229 C CG2   . THR B 2 444 ? 255.448 150.864 228.765 1.00 78.77  ? 447 THR C CG2   1 
ATOM   6230 N N     . LEU B 2 445 ? 258.088 152.924 229.591 1.00 82.85  ? 448 LEU C N     1 
ATOM   6231 C CA    . LEU B 2 445 ? 259.403 153.290 229.077 1.00 82.85  ? 448 LEU C CA    1 
ATOM   6232 C C     . LEU B 2 445 ? 260.112 154.331 229.933 1.00 82.85  ? 448 LEU C C     1 
ATOM   6233 O O     . LEU B 2 445 ? 261.136 154.871 229.505 1.00 82.85  ? 448 LEU C O     1 
ATOM   6234 C CB    . LEU B 2 445 ? 259.301 153.805 227.639 1.00 82.85  ? 448 LEU C CB    1 
ATOM   6235 C CG    . LEU B 2 445 ? 259.339 152.807 226.483 1.00 82.85  ? 448 LEU C CG    1 
ATOM   6236 C CD1   . LEU B 2 445 ? 258.084 151.970 226.422 1.00 82.85  ? 448 LEU C CD1   1 
ATOM   6237 C CD2   . LEU B 2 445 ? 259.530 153.556 225.186 1.00 82.85  ? 448 LEU C CD2   1 
ATOM   6238 N N     . GLU B 2 446 ? 259.603 154.626 231.125 1.00 90.74  ? 449 GLU C N     1 
ATOM   6239 C CA    . GLU B 2 446 ? 260.136 155.698 231.961 1.00 90.74  ? 449 GLU C CA    1 
ATOM   6240 C C     . GLU B 2 446 ? 260.906 155.089 233.123 1.00 90.74  ? 449 GLU C C     1 
ATOM   6241 O O     . GLU B 2 446 ? 260.303 154.555 234.060 1.00 90.74  ? 449 GLU C O     1 
ATOM   6242 C CB    . GLU B 2 446 ? 259.015 156.603 232.471 1.00 90.74  ? 449 GLU C CB    1 
ATOM   6243 C CG    . GLU B 2 446 ? 259.458 158.010 232.842 1.00 90.74  ? 449 GLU C CG    1 
ATOM   6244 C CD    . GLU B 2 446 ? 260.310 158.050 234.092 1.00 90.74  ? 449 GLU C CD    1 
ATOM   6245 O OE1   . GLU B 2 446 ? 260.031 157.271 235.027 1.00 90.74  ? 449 GLU C OE1   1 
ATOM   6246 O OE2   . GLU B 2 446 ? 261.259 158.860 234.135 1.00 90.74  ? 449 GLU C OE2   1 
ATOM   6247 N N     . THR B 2 447 ? 262.235 155.172 233.061 1.00 97.20  ? 450 THR C N     1 
ATOM   6248 C CA    . THR B 2 447 ? 263.075 154.852 234.213 1.00 97.20  ? 450 THR C CA    1 
ATOM   6249 C C     . THR B 2 447 ? 264.445 155.489 234.016 1.00 97.20  ? 450 THR C C     1 
ATOM   6250 O O     . THR B 2 447 ? 265.201 155.066 233.136 1.00 97.20  ? 450 THR C O     1 
ATOM   6251 C CB    . THR B 2 447 ? 263.174 153.336 234.418 1.00 97.20  ? 450 THR C CB    1 
ATOM   6252 O OG1   . THR B 2 447 ? 264.075 153.045 235.495 1.00 97.20  ? 450 THR C OG1   1 
ATOM   6253 C CG2   . THR B 2 447 ? 263.593 152.599 233.142 1.00 97.20  ? 450 THR C CG2   1 
ATOM   6254 N N     . LYS B 2 448 ? 264.749 156.515 234.815 1.00 101.34 ? 451 LYS C N     1 
ATOM   6255 C CA    . LYS B 2 448 ? 266.095 157.077 234.913 1.00 101.34 ? 451 LYS C CA    1 
ATOM   6256 C C     . LYS B 2 448 ? 266.084 158.200 235.947 1.00 101.34 ? 451 LYS C C     1 
ATOM   6257 O O     . LYS B 2 448 ? 265.035 158.581 236.475 1.00 101.34 ? 451 LYS C O     1 
ATOM   6258 C CB    . LYS B 2 448 ? 266.630 157.598 233.575 1.00 101.34 ? 451 LYS C CB    1 
ATOM   6259 C CG    . LYS B 2 448 ? 268.150 157.569 233.477 1.00 101.34 ? 451 LYS C CG    1 
ATOM   6260 C CD    . LYS B 2 448 ? 268.714 156.370 234.222 1.00 101.34 ? 451 LYS C CD    1 
ATOM   6261 C CE    . LYS B 2 448 ? 270.223 156.441 234.321 1.00 101.34 ? 451 LYS C CE    1 
ATOM   6262 N NZ    . LYS B 2 448 ? 270.784 155.266 235.039 1.00 101.34 ? 451 LYS C NZ    1 
ATOM   6263 N N     . GLN B 2 449 ? 267.281 158.711 236.234 1.00 105.10 ? 452 GLN C N     1 
ATOM   6264 C CA    . GLN B 2 449 ? 267.469 159.879 237.075 1.00 105.10 ? 452 GLN C CA    1 
ATOM   6265 C C     . GLN B 2 449 ? 267.265 161.157 236.255 1.00 105.10 ? 452 GLN C C     1 
ATOM   6266 O O     . GLN B 2 449 ? 267.196 161.102 235.025 1.00 105.10 ? 452 GLN C O     1 
ATOM   6267 C CB    . GLN B 2 449 ? 268.865 159.827 237.699 1.00 105.10 ? 452 GLN C CB    1 
ATOM   6268 C CG    . GLN B 2 449 ? 270.005 159.773 236.695 1.00 105.10 ? 452 GLN C CG    1 
ATOM   6269 C CD    . GLN B 2 449 ? 270.469 161.142 236.266 1.00 105.10 ? 452 GLN C CD    1 
ATOM   6270 O OE1   . GLN B 2 449 ? 270.369 162.104 237.023 1.00 105.10 ? 452 GLN C OE1   1 
ATOM   6271 N NE2   . GLN B 2 449 ? 270.988 161.238 235.048 1.00 105.10 ? 452 GLN C NE2   1 
ATOM   6272 N N     . PRO B 2 450 ? 267.149 162.317 236.913 1.00 105.13 ? 453 PRO C N     1 
ATOM   6273 C CA    . PRO B 2 450 ? 266.852 163.560 236.179 1.00 105.13 ? 453 PRO C CA    1 
ATOM   6274 C C     . PRO B 2 450 ? 267.830 163.824 235.040 1.00 105.13 ? 453 PRO C C     1 
ATOM   6275 O O     . PRO B 2 450 ? 268.993 163.418 235.078 1.00 105.13 ? 453 PRO C O     1 
ATOM   6276 C CB    . PRO B 2 450 ? 266.935 164.647 237.262 1.00 105.13 ? 453 PRO C CB    1 
ATOM   6277 C CG    . PRO B 2 450 ? 267.463 163.965 238.497 1.00 105.13 ? 453 PRO C CG    1 
ATOM   6278 C CD    . PRO B 2 450 ? 267.070 162.535 238.367 1.00 105.13 ? 453 PRO C CD    1 
ATOM   6279 N N     . ARG B 2 451 ? 267.331 164.510 234.018 1.00 94.64  ? 454 ARG C N     1 
ATOM   6280 C CA    . ARG B 2 451 ? 267.977 164.631 232.725 1.00 94.64  ? 454 ARG C CA    1 
ATOM   6281 C C     . ARG B 2 451 ? 267.767 166.034 232.170 1.00 94.64  ? 454 ARG C C     1 
ATOM   6282 O O     . ARG B 2 451 ? 266.759 166.687 232.448 1.00 94.64  ? 454 ARG C O     1 
ATOM   6283 C CB    . ARG B 2 451 ? 267.403 163.571 231.797 1.00 94.64  ? 454 ARG C CB    1 
ATOM   6284 C CG    . ARG B 2 451 ? 265.901 163.700 231.687 1.00 94.64  ? 454 ARG C CG    1 
ATOM   6285 C CD    . ARG B 2 451 ? 265.266 162.394 231.243 1.00 94.64  ? 454 ARG C CD    1 
ATOM   6286 N NE    . ARG B 2 451 ? 263.832 162.534 230.982 1.00 94.64  ? 454 ARG C NE    1 
ATOM   6287 C CZ    . ARG B 2 451 ? 262.876 162.408 231.898 1.00 94.64  ? 454 ARG C CZ    1 
ATOM   6288 N NH1   . ARG B 2 451 ? 263.189 162.135 233.156 1.00 94.64  ? 454 ARG C NH1   1 
ATOM   6289 N NH2   . ARG B 2 451 ? 261.606 162.552 231.557 1.00 94.64  ? 454 ARG C NH2   1 
ATOM   6290 N N     . GLN B 2 452 ? 268.720 166.499 231.364 1.00 90.05  ? 455 GLN C N     1 
ATOM   6291 C CA    . GLN B 2 452 ? 268.710 167.892 230.925 1.00 90.05  ? 455 GLN C CA    1 
ATOM   6292 C C     . GLN B 2 452 ? 268.151 168.075 229.518 1.00 90.05  ? 455 GLN C C     1 
ATOM   6293 O O     . GLN B 2 452 ? 267.173 168.804 229.328 1.00 90.05  ? 455 GLN C O     1 
ATOM   6294 C CB    . GLN B 2 452 ? 270.122 168.485 231.001 1.00 90.05  ? 455 GLN C CB    1 
ATOM   6295 C CG    . GLN B 2 452 ? 270.659 168.668 232.407 1.00 90.05  ? 455 GLN C CG    1 
ATOM   6296 C CD    . GLN B 2 452 ? 272.132 169.024 232.408 1.00 90.05  ? 455 GLN C CD    1 
ATOM   6297 O OE1   . GLN B 2 452 ? 272.817 168.862 231.399 1.00 90.05  ? 455 GLN C OE1   1 
ATOM   6298 N NE2   . GLN B 2 452 ? 272.627 169.511 233.540 1.00 90.05  ? 455 GLN C NE2   1 
ATOM   6299 N N     . TYR B 2 453 ? 268.761 167.440 228.523 1.00 84.06  ? 456 TYR C N     1 
ATOM   6300 C CA    . TYR B 2 453 ? 268.441 167.716 227.132 1.00 84.06  ? 456 TYR C CA    1 
ATOM   6301 C C     . TYR B 2 453 ? 267.988 166.443 226.431 1.00 84.06  ? 456 TYR C C     1 
ATOM   6302 O O     . TYR B 2 453 ? 268.099 165.338 226.965 1.00 84.06  ? 456 TYR C O     1 
ATOM   6303 C CB    . TYR B 2 453 ? 269.642 168.338 226.417 1.00 84.06  ? 456 TYR C CB    1 
ATOM   6304 C CG    . TYR B 2 453 ? 270.042 169.657 227.027 1.00 84.06  ? 456 TYR C CG    1 
ATOM   6305 C CD1   . TYR B 2 453 ? 269.287 170.798 226.803 1.00 84.06  ? 456 TYR C CD1   1 
ATOM   6306 C CD2   . TYR B 2 453 ? 271.169 169.764 227.825 1.00 84.06  ? 456 TYR C CD2   1 
ATOM   6307 C CE1   . TYR B 2 453 ? 269.636 172.007 227.360 1.00 84.06  ? 456 TYR C CE1   1 
ATOM   6308 C CE2   . TYR B 2 453 ? 271.529 170.973 228.386 1.00 84.06  ? 456 TYR C CE2   1 
ATOM   6309 C CZ    . TYR B 2 453 ? 270.757 172.092 228.148 1.00 84.06  ? 456 TYR C CZ    1 
ATOM   6310 O OH    . TYR B 2 453 ? 271.103 173.302 228.701 1.00 84.06  ? 456 TYR C OH    1 
ATOM   6311 N N     . PHE B 2 454 ? 267.468 166.612 225.216 1.00 74.01  ? 457 PHE C N     1 
ATOM   6312 C CA    . PHE B 2 454 ? 266.909 165.493 224.475 1.00 74.01  ? 457 PHE C CA    1 
ATOM   6313 C C     . PHE B 2 454 ? 267.070 165.722 222.980 1.00 74.01  ? 457 PHE C C     1 
ATOM   6314 O O     . PHE B 2 454 ? 267.383 166.825 222.526 1.00 74.01  ? 457 PHE C O     1 
ATOM   6315 C CB    . PHE B 2 454 ? 265.433 165.272 224.828 1.00 74.01  ? 457 PHE C CB    1 
ATOM   6316 C CG    . PHE B 2 454 ? 264.504 166.268 224.203 1.00 74.01  ? 457 PHE C CG    1 
ATOM   6317 C CD1   . PHE B 2 454 ? 264.339 167.522 224.757 1.00 74.01  ? 457 PHE C CD1   1 
ATOM   6318 C CD2   . PHE B 2 454 ? 263.789 165.947 223.064 1.00 74.01  ? 457 PHE C CD2   1 
ATOM   6319 C CE1   . PHE B 2 454 ? 263.483 168.440 224.183 1.00 74.01  ? 457 PHE C CE1   1 
ATOM   6320 C CE2   . PHE B 2 454 ? 262.936 166.863 222.486 1.00 74.01  ? 457 PHE C CE2   1 
ATOM   6321 C CZ    . PHE B 2 454 ? 262.782 168.110 223.046 1.00 74.01  ? 457 PHE C CZ    1 
ATOM   6322 N N     . ILE B 2 455 ? 266.855 164.651 222.221 1.00 72.02  ? 458 ILE C N     1 
ATOM   6323 C CA    . ILE B 2 455 ? 266.842 164.679 220.764 1.00 72.02  ? 458 ILE C CA    1 
ATOM   6324 C C     . ILE B 2 455 ? 265.504 164.119 220.310 1.00 72.02  ? 458 ILE C C     1 
ATOM   6325 O O     . ILE B 2 455 ? 265.231 162.928 220.499 1.00 72.02  ? 458 ILE C O     1 
ATOM   6326 C CB    . ILE B 2 455 ? 267.990 163.859 220.160 1.00 72.02  ? 458 ILE C CB    1 
ATOM   6327 C CG1   . ILE B 2 455 ? 269.344 164.338 220.674 1.00 72.02  ? 458 ILE C CG1   1 
ATOM   6328 C CG2   . ILE B 2 455 ? 267.952 163.967 218.655 1.00 72.02  ? 458 ILE C CG2   1 
ATOM   6329 C CD1   . ILE B 2 455 ? 269.692 165.725 220.254 1.00 72.02  ? 458 ILE C CD1   1 
ATOM   6330 N N     . GLY B 2 456 ? 264.676 164.964 219.709 1.00 67.22  ? 459 GLY C N     1 
ATOM   6331 C CA    . GLY B 2 456 ? 263.363 164.554 219.241 1.00 67.22  ? 459 GLY C CA    1 
ATOM   6332 C C     . GLY B 2 456 ? 263.414 164.068 217.803 1.00 67.22  ? 459 GLY C C     1 
ATOM   6333 O O     . GLY B 2 456 ? 264.166 164.596 216.985 1.00 67.22  ? 459 GLY C O     1 
ATOM   6334 N N     . VAL B 2 457 ? 262.611 163.052 217.510 1.00 63.08  ? 460 VAL C N     1 
ATOM   6335 C CA    . VAL B 2 457 ? 262.488 162.502 216.165 1.00 63.08  ? 460 VAL C CA    1 
ATOM   6336 C C     . VAL B 2 457 ? 261.026 162.641 215.764 1.00 63.08  ? 460 VAL C C     1 
ATOM   6337 O O     . VAL B 2 457 ? 260.209 161.755 216.041 1.00 63.08  ? 460 VAL C O     1 
ATOM   6338 C CB    . VAL B 2 457 ? 262.953 161.046 216.090 1.00 63.08  ? 460 VAL C CB    1 
ATOM   6339 C CG1   . VAL B 2 457 ? 262.954 160.568 214.653 1.00 63.08  ? 460 VAL C CG1   1 
ATOM   6340 C CG2   . VAL B 2 457 ? 264.330 160.908 216.695 1.00 63.08  ? 460 VAL C CG2   1 
ATOM   6341 N N     . LEU B 2 458 ? 260.690 163.740 215.098 1.00 62.57  ? 461 LEU C N     1 
ATOM   6342 C CA    . LEU B 2 458 ? 259.312 164.032 214.734 1.00 62.57  ? 461 LEU C CA    1 
ATOM   6343 C C     . LEU B 2 458 ? 258.961 163.306 213.444 1.00 62.57  ? 461 LEU C C     1 
ATOM   6344 O O     . LEU B 2 458 ? 259.648 163.459 212.431 1.00 62.57  ? 461 LEU C O     1 
ATOM   6345 C CB    . LEU B 2 458 ? 259.098 165.535 214.577 1.00 62.57  ? 461 LEU C CB    1 
ATOM   6346 C CG    . LEU B 2 458 ? 257.724 165.940 214.048 1.00 62.57  ? 461 LEU C CG    1 
ATOM   6347 C CD1   . LEU B 2 458 ? 256.634 165.447 214.977 1.00 62.57  ? 461 LEU C CD1   1 
ATOM   6348 C CD2   . LEU B 2 458 ? 257.639 167.440 213.872 1.00 62.57  ? 461 LEU C CD2   1 
ATOM   6349 N N     . ASP B 2 459 ? 257.892 162.522 213.486 1.00 69.10  ? 462 ASP C N     1 
ATOM   6350 C CA    . ASP B 2 459 ? 257.404 161.775 212.338 1.00 69.10  ? 462 ASP C CA    1 
ATOM   6351 C C     . ASP B 2 459 ? 255.941 162.119 212.108 1.00 69.10  ? 462 ASP C C     1 
ATOM   6352 O O     . ASP B 2 459 ? 255.093 161.826 212.955 1.00 69.10  ? 462 ASP C O     1 
ATOM   6353 C CB    . ASP B 2 459 ? 257.572 160.273 212.566 1.00 69.10  ? 462 ASP C CB    1 
ATOM   6354 C CG    . ASP B 2 459 ? 257.093 159.456 211.397 1.00 69.10  ? 462 ASP C CG    1 
ATOM   6355 O OD1   . ASP B 2 459 ? 256.687 158.293 211.606 1.00 69.10  ? 462 ASP C OD1   1 
ATOM   6356 O OD2   . ASP B 2 459 ? 257.115 159.981 210.268 1.00 69.10  ? 462 ASP C OD2   1 
ATOM   6357 N N     . ILE B 2 460 ? 255.642 162.725 210.960 1.00 70.09  ? 463 ILE C N     1 
ATOM   6358 C CA    . ILE B 2 460 ? 254.306 163.241 210.693 1.00 70.09  ? 463 ILE C CA    1 
ATOM   6359 C C     . ILE B 2 460 ? 254.008 163.085 209.209 1.00 70.09  ? 463 ILE C C     1 
ATOM   6360 O O     . ILE B 2 460 ? 254.910 163.115 208.369 1.00 70.09  ? 463 ILE C O     1 
ATOM   6361 C CB    . ILE B 2 460 ? 254.181 164.713 211.151 1.00 70.09  ? 463 ILE C CB    1 
ATOM   6362 C CG1   . ILE B 2 460 ? 252.719 165.144 211.207 1.00 70.09  ? 463 ILE C CG1   1 
ATOM   6363 C CG2   . ILE B 2 460 ? 254.972 165.628 210.237 1.00 70.09  ? 463 ILE C CG2   1 
ATOM   6364 C CD1   . ILE B 2 460 ? 252.504 166.422 211.974 1.00 70.09  ? 463 ILE C CD1   1 
ATOM   6365 N N     . ALA B 2 461 ? 252.727 162.907 208.893 1.00 73.21  ? 464 ALA C N     1 
ATOM   6366 C CA    . ALA B 2 461 ? 252.311 162.682 207.515 1.00 73.21  ? 464 ALA C CA    1 
ATOM   6367 C C     . ALA B 2 461 ? 252.554 163.922 206.666 1.00 73.21  ? 464 ALA C C     1 
ATOM   6368 O O     . ALA B 2 461 ? 252.326 165.052 207.104 1.00 73.21  ? 464 ALA C O     1 
ATOM   6369 C CB    . ALA B 2 461 ? 250.835 162.294 207.466 1.00 73.21  ? 464 ALA C CB    1 
ATOM   6370 N N     . GLY B 2 462 ? 253.010 163.703 205.435 1.00 71.19  ? 465 GLY C N     1 
ATOM   6371 C CA    . GLY B 2 462 ? 253.448 164.777 204.571 1.00 71.19  ? 465 GLY C CA    1 
ATOM   6372 C C     . GLY B 2 462 ? 252.361 165.270 203.638 1.00 71.19  ? 465 GLY C C     1 
ATOM   6373 O O     . GLY B 2 462 ? 251.196 164.880 203.721 1.00 71.19  ? 465 GLY C O     1 
ATOM   6374 N N     . PHE B 2 463 ? 252.769 166.157 202.732 1.00 66.63  ? 466 PHE C N     1 
ATOM   6375 C CA    . PHE B 2 463 ? 251.846 166.782 201.797 1.00 66.63  ? 466 PHE C CA    1 
ATOM   6376 C C     . PHE B 2 463 ? 251.096 165.731 200.992 1.00 66.63  ? 466 PHE C C     1 
ATOM   6377 O O     . PHE B 2 463 ? 251.606 164.643 200.718 1.00 66.63  ? 466 PHE C O     1 
ATOM   6378 C CB    . PHE B 2 463 ? 252.604 167.716 200.860 1.00 66.63  ? 466 PHE C CB    1 
ATOM   6379 C CG    . PHE B 2 463 ? 251.816 168.910 200.429 1.00 66.63  ? 466 PHE C CG    1 
ATOM   6380 C CD1   . PHE B 2 463 ? 251.128 168.907 199.233 1.00 66.63  ? 466 PHE C CD1   1 
ATOM   6381 C CD2   . PHE B 2 463 ? 251.767 170.040 201.221 1.00 66.63  ? 466 PHE C CD2   1 
ATOM   6382 C CE1   . PHE B 2 463 ? 250.406 170.008 198.836 1.00 66.63  ? 466 PHE C CE1   1 
ATOM   6383 C CE2   . PHE B 2 463 ? 251.046 171.140 200.828 1.00 66.63  ? 466 PHE C CE2   1 
ATOM   6384 C CZ    . PHE B 2 463 ? 250.364 171.123 199.634 1.00 66.63  ? 466 PHE C CZ    1 
ATOM   6385 N N     . GLU B 2 464 ? 249.866 166.065 200.611 1.00 70.53  ? 467 GLU C N     1 
ATOM   6386 C CA    . GLU B 2 464 ? 248.976 165.131 199.935 1.00 70.53  ? 467 GLU C CA    1 
ATOM   6387 C C     . GLU B 2 464 ? 248.308 165.832 198.766 1.00 70.53  ? 467 GLU C C     1 
ATOM   6388 O O     . GLU B 2 464 ? 247.593 166.819 198.959 1.00 70.53  ? 467 GLU C O     1 
ATOM   6389 C CB    . GLU B 2 464 ? 247.918 164.589 200.895 1.00 70.53  ? 467 GLU C CB    1 
ATOM   6390 C CG    . GLU B 2 464 ? 248.285 163.279 201.547 1.00 70.53  ? 467 GLU C CG    1 
ATOM   6391 C CD    . GLU B 2 464 ? 247.346 162.929 202.676 1.00 70.53  ? 467 GLU C CD    1 
ATOM   6392 O OE1   . GLU B 2 464 ? 246.687 163.852 203.193 1.00 70.53  ? 467 GLU C OE1   1 
ATOM   6393 O OE2   . GLU B 2 464 ? 247.265 161.739 203.045 1.00 70.53  ? 467 GLU C OE2   1 
ATOM   6394 N N     . ILE B 2 465 ? 248.534 165.318 197.562 1.00 70.74  ? 468 ILE C N     1 
ATOM   6395 C CA    . ILE B 2 465 ? 247.859 165.795 196.357 1.00 70.74  ? 468 ILE C CA    1 
ATOM   6396 C C     . ILE B 2 465 ? 247.213 164.570 195.717 1.00 70.74  ? 468 ILE C C     1 
ATOM   6397 O O     . ILE B 2 465 ? 247.855 163.826 194.970 1.00 70.74  ? 468 ILE C O     1 
ATOM   6398 C CB    . ILE B 2 465 ? 248.809 166.495 195.382 1.00 70.74  ? 468 ILE C CB    1 
ATOM   6399 C CG1   . ILE B 2 465 ? 249.519 167.655 196.076 1.00 70.74  ? 468 ILE C CG1   1 
ATOM   6400 C CG2   . ILE B 2 465 ? 248.045 166.986 194.169 1.00 70.74  ? 468 ILE C CG2   1 
ATOM   6401 C CD1   . ILE B 2 465 ? 250.275 168.555 195.132 1.00 70.74  ? 468 ILE C CD1   1 
ATOM   6402 N N     . PHE B 2 466 ? 245.940 164.347 196.015 1.00 72.56  ? 469 PHE C N     1 
ATOM   6403 C CA    . PHE B 2 466 ? 245.187 163.250 195.438 1.00 72.56  ? 469 PHE C CA    1 
ATOM   6404 C C     . PHE B 2 466 ? 244.397 163.748 194.235 1.00 72.56  ? 469 PHE C C     1 
ATOM   6405 O O     . PHE B 2 466 ? 244.437 164.925 193.873 1.00 72.56  ? 469 PHE C O     1 
ATOM   6406 C CB    . PHE B 2 466 ? 244.250 162.635 196.476 1.00 72.56  ? 469 PHE C CB    1 
ATOM   6407 C CG    . PHE B 2 466 ? 244.955 162.028 197.646 1.00 72.56  ? 469 PHE C CG    1 
ATOM   6408 C CD1   . PHE B 2 466 ? 246.229 161.512 197.512 1.00 72.56  ? 469 PHE C CD1   1 
ATOM   6409 C CD2   . PHE B 2 466 ? 244.343 161.972 198.882 1.00 72.56  ? 469 PHE C CD2   1 
ATOM   6410 C CE1   . PHE B 2 466 ? 246.876 160.952 198.589 1.00 72.56  ? 469 PHE C CE1   1 
ATOM   6411 C CE2   . PHE B 2 466 ? 244.986 161.415 199.960 1.00 72.56  ? 469 PHE C CE2   1 
ATOM   6412 C CZ    . PHE B 2 466 ? 246.253 160.904 199.814 1.00 72.56  ? 469 PHE C CZ    1 
ATOM   6413 N N     . ASP B 2 467 ? 243.665 162.831 193.607 1.00 77.72  ? 470 ASP C N     1 
ATOM   6414 C CA    . ASP B 2 467 ? 242.714 163.224 192.580 1.00 77.72  ? 470 ASP C CA    1 
ATOM   6415 C C     . ASP B 2 467 ? 241.461 163.847 193.173 1.00 77.72  ? 470 ASP C C     1 
ATOM   6416 O O     . ASP B 2 467 ? 240.819 164.669 192.512 1.00 77.72  ? 470 ASP C O     1 
ATOM   6417 C CB    . ASP B 2 467 ? 242.342 162.018 191.720 1.00 77.72  ? 470 ASP C CB    1 
ATOM   6418 C CG    . ASP B 2 467 ? 242.129 160.765 192.542 1.00 77.72  ? 470 ASP C CG    1 
ATOM   6419 O OD1   . ASP B 2 467 ? 242.154 159.660 191.962 1.00 77.72  ? 470 ASP C OD1   1 
ATOM   6420 O OD2   . ASP B 2 467 ? 241.938 160.884 193.770 1.00 77.72  ? 470 ASP C OD2   1 
ATOM   6421 N N     . PHE B 2 468 ? 241.108 163.482 194.404 1.00 75.38  ? 471 PHE C N     1 
ATOM   6422 C CA    . PHE B 2 468 ? 239.950 164.043 195.098 1.00 75.38  ? 471 PHE C CA    1 
ATOM   6423 C C     . PHE B 2 468 ? 240.406 164.460 196.492 1.00 75.38  ? 471 PHE C C     1 
ATOM   6424 O O     . PHE B 2 468 ? 240.576 163.612 197.373 1.00 75.38  ? 471 PHE C O     1 
ATOM   6425 C CB    . PHE B 2 468 ? 238.807 163.038 195.159 1.00 75.38  ? 471 PHE C CB    1 
ATOM   6426 C CG    . PHE B 2 468 ? 237.613 163.524 195.925 1.00 75.38  ? 471 PHE C CG    1 
ATOM   6427 C CD1   . PHE B 2 468 ? 236.654 164.307 195.313 1.00 75.38  ? 471 PHE C CD1   1 
ATOM   6428 C CD2   . PHE B 2 468 ? 237.445 163.190 197.256 1.00 75.38  ? 471 PHE C CD2   1 
ATOM   6429 C CE1   . PHE B 2 468 ? 235.557 164.752 196.014 1.00 75.38  ? 471 PHE C CE1   1 
ATOM   6430 C CE2   . PHE B 2 468 ? 236.349 163.634 197.960 1.00 75.38  ? 471 PHE C CE2   1 
ATOM   6431 C CZ    . PHE B 2 468 ? 235.405 164.415 197.339 1.00 75.38  ? 471 PHE C CZ    1 
ATOM   6432 N N     . ASN B 2 469 ? 240.605 165.759 196.686 1.00 68.87  ? 472 ASN C N     1 
ATOM   6433 C CA    . ASN B 2 469 ? 241.027 166.309 197.965 1.00 68.87  ? 472 ASN C CA    1 
ATOM   6434 C C     . ASN B 2 469 ? 239.826 166.827 198.742 1.00 68.87  ? 472 ASN C C     1 
ATOM   6435 O O     . ASN B 2 469 ? 238.851 167.311 198.164 1.00 68.87  ? 472 ASN C O     1 
ATOM   6436 C CB    . ASN B 2 469 ? 242.040 167.433 197.764 1.00 68.87  ? 472 ASN C CB    1 
ATOM   6437 C CG    . ASN B 2 469 ? 243.262 166.976 197.012 1.00 68.87  ? 472 ASN C CG    1 
ATOM   6438 O OD1   . ASN B 2 469 ? 244.049 166.180 197.517 1.00 68.87  ? 472 ASN C OD1   1 
ATOM   6439 N ND2   . ASN B 2 469 ? 243.429 167.472 195.796 1.00 68.87  ? 472 ASN C ND2   1 
ATOM   6440 N N     . SER B 2 470 ? 239.908 166.730 200.063 1.00 66.55  ? 473 SER C N     1 
ATOM   6441 C CA    . SER B 2 470 ? 238.779 167.032 200.933 1.00 66.55  ? 473 SER C CA    1 
ATOM   6442 C C     . SER B 2 470 ? 239.297 167.762 202.167 1.00 66.55  ? 473 SER C C     1 
ATOM   6443 O O     . SER B 2 470 ? 240.423 168.268 202.193 1.00 66.55  ? 473 SER C O     1 
ATOM   6444 C CB    . SER B 2 470 ? 238.010 165.751 201.281 1.00 66.55  ? 473 SER C CB    1 
ATOM   6445 O OG    . SER B 2 470 ? 236.743 166.060 201.831 1.00 66.55  ? 473 SER C OG    1 
ATOM   6446 N N     . PHE B 2 471 ? 238.454 167.831 203.197 1.00 64.44  ? 474 PHE C N     1 
ATOM   6447 C CA    . PHE B 2 471 ? 238.784 168.580 204.407 1.00 64.44  ? 474 PHE C CA    1 
ATOM   6448 C C     . PHE B 2 471 ? 240.050 168.050 205.072 1.00 64.44  ? 474 PHE C C     1 
ATOM   6449 O O     . PHE B 2 471 ? 240.907 168.830 205.511 1.00 64.44  ? 474 PHE C O     1 
ATOM   6450 C CB    . PHE B 2 471 ? 237.598 168.524 205.368 1.00 64.44  ? 474 PHE C CB    1 
ATOM   6451 C CG    . PHE B 2 471 ? 237.853 169.165 206.692 1.00 64.44  ? 474 PHE C CG    1 
ATOM   6452 C CD1   . PHE B 2 471 ? 238.295 170.469 206.772 1.00 64.44  ? 474 PHE C CD1   1 
ATOM   6453 C CD2   . PHE B 2 471 ? 237.633 168.466 207.860 1.00 64.44  ? 474 PHE C CD2   1 
ATOM   6454 C CE1   . PHE B 2 471 ? 238.524 171.061 207.994 1.00 64.44  ? 474 PHE C CE1   1 
ATOM   6455 C CE2   . PHE B 2 471 ? 237.860 169.052 209.083 1.00 64.44  ? 474 PHE C CE2   1 
ATOM   6456 C CZ    . PHE B 2 471 ? 238.306 170.352 209.150 1.00 64.44  ? 474 PHE C CZ    1 
ATOM   6457 N N     . GLU B 2 472 ? 240.186 166.725 205.155 1.00 67.75  ? 475 GLU C N     1 
ATOM   6458 C CA    . GLU B 2 472 ? 241.357 166.138 205.798 1.00 67.75  ? 475 GLU C CA    1 
ATOM   6459 C C     . GLU B 2 472 ? 242.633 166.501 205.053 1.00 67.75  ? 475 GLU C C     1 
ATOM   6460 O O     . GLU B 2 472 ? 243.669 166.783 205.672 1.00 67.75  ? 475 GLU C O     1 
ATOM   6461 C CB    . GLU B 2 472 ? 241.201 164.620 205.880 1.00 67.75  ? 475 GLU C CB    1 
ATOM   6462 C CG    . GLU B 2 472 ? 239.975 164.146 206.648 1.00 67.75  ? 475 GLU C CG    1 
ATOM   6463 C CD    . GLU B 2 472 ? 238.690 164.262 205.850 1.00 67.75  ? 475 GLU C CD    1 
ATOM   6464 O OE1   . GLU B 2 472 ? 237.617 163.923 206.392 1.00 67.75  ? 475 GLU C OE1   1 
ATOM   6465 O OE2   . GLU B 2 472 ? 238.752 164.692 204.680 1.00 67.75  ? 475 GLU C OE2   1 
ATOM   6466 N N     . GLN B 2 473 ? 242.577 166.500 203.722 1.00 65.69  ? 476 GLN C N     1 
ATOM   6467 C CA    . GLN B 2 473 ? 243.740 166.904 202.946 1.00 65.69  ? 476 GLN C CA    1 
ATOM   6468 C C     . GLN B 2 473 ? 244.073 168.365 203.191 1.00 65.69  ? 476 GLN C C     1 
ATOM   6469 O O     . GLN B 2 473 ? 245.248 168.741 203.234 1.00 65.69  ? 476 GLN C O     1 
ATOM   6470 C CB    . GLN B 2 473 ? 243.500 166.647 201.460 1.00 65.69  ? 476 GLN C CB    1 
ATOM   6471 C CG    . GLN B 2 473 ? 243.717 165.210 201.034 1.00 65.69  ? 476 GLN C CG    1 
ATOM   6472 C CD    . GLN B 2 473 ? 242.730 164.260 201.666 1.00 65.69  ? 476 GLN C CD    1 
ATOM   6473 O OE1   . GLN B 2 473 ? 241.576 164.179 201.251 1.00 65.69  ? 476 GLN C OE1   1 
ATOM   6474 N NE2   . GLN B 2 473 ? 243.177 163.532 202.678 1.00 65.69  ? 476 GLN C NE2   1 
ATOM   6475 N N     . LEU B 2 474 ? 243.055 169.204 203.379 1.00 61.97  ? 477 LEU C N     1 
ATOM   6476 C CA    . LEU B 2 474 ? 243.318 170.605 203.682 1.00 61.97  ? 477 LEU C CA    1 
ATOM   6477 C C     . LEU B 2 474 ? 244.020 170.749 205.023 1.00 61.97  ? 477 LEU C C     1 
ATOM   6478 O O     . LEU B 2 474 ? 244.964 171.535 205.157 1.00 61.97  ? 477 LEU C O     1 
ATOM   6479 C CB    . LEU B 2 474 ? 242.018 171.403 203.671 1.00 61.97  ? 477 LEU C CB    1 
ATOM   6480 C CG    . LEU B 2 474 ? 242.179 172.887 203.991 1.00 61.97  ? 477 LEU C CG    1 
ATOM   6481 C CD1   . LEU B 2 474 ? 243.160 173.525 203.035 1.00 61.97  ? 477 LEU C CD1   1 
ATOM   6482 C CD2   . LEU B 2 474 ? 240.846 173.599 203.938 1.00 61.97  ? 477 LEU C CD2   1 
ATOM   6483 N N     . CYS B 2 475 ? 243.589 169.979 206.023 1.00 64.09  ? 478 CYS C N     1 
ATOM   6484 C CA    . CYS B 2 475 ? 244.236 170.048 207.331 1.00 64.09  ? 478 CYS C CA    1 
ATOM   6485 C C     . CYS B 2 475 ? 245.688 169.588 207.257 1.00 64.09  ? 478 CYS C C     1 
ATOM   6486 O O     . CYS B 2 475 ? 246.588 170.237 207.812 1.00 64.09  ? 478 CYS C O     1 
ATOM   6487 C CB    . CYS B 2 475 ? 243.455 169.209 208.339 1.00 64.09  ? 478 CYS C CB    1 
ATOM   6488 S SG    . CYS B 2 475 ? 242.063 170.067 209.095 1.00 64.09  ? 478 CYS C SG    1 
ATOM   6489 N N     . ILE B 2 476 ? 245.938 168.477 206.565 1.00 63.33  ? 479 ILE C N     1 
ATOM   6490 C CA    . ILE B 2 476 ? 247.300 167.956 206.468 1.00 63.33  ? 479 ILE C CA    1 
ATOM   6491 C C     . ILE B 2 476 ? 248.195 168.916 205.689 1.00 63.33  ? 479 ILE C C     1 
ATOM   6492 O O     . ILE B 2 476 ? 249.350 169.158 206.068 1.00 63.33  ? 479 ILE C O     1 
ATOM   6493 C CB    . ILE B 2 476 ? 247.285 166.549 205.848 1.00 63.33  ? 479 ILE C CB    1 
ATOM   6494 C CG1   . ILE B 2 476 ? 246.469 165.607 206.733 1.00 63.33  ? 479 ILE C CG1   1 
ATOM   6495 C CG2   . ILE B 2 476 ? 248.689 166.026 205.681 1.00 63.33  ? 479 ILE C CG2   1 
ATOM   6496 C CD1   . ILE B 2 476 ? 246.548 164.162 206.338 1.00 63.33  ? 479 ILE C CD1   1 
ATOM   6497 N N     . ASN B 2 477 ? 247.680 169.491 204.602 1.00 63.61  ? 480 ASN C N     1 
ATOM   6498 C CA    . ASN B 2 477 ? 248.472 170.444 203.838 1.00 63.61  ? 480 ASN C CA    1 
ATOM   6499 C C     . ASN B 2 477 ? 248.728 171.719 204.625 1.00 63.61  ? 480 ASN C C     1 
ATOM   6500 O O     . ASN B 2 477 ? 249.783 172.333 204.463 1.00 63.61  ? 480 ASN C O     1 
ATOM   6501 C CB    . ASN B 2 477 ? 247.783 170.762 202.514 1.00 63.61  ? 480 ASN C CB    1 
ATOM   6502 C CG    . ASN B 2 477 ? 247.643 169.545 201.630 1.00 63.61  ? 480 ASN C CG    1 
ATOM   6503 O OD1   . ASN B 2 477 ? 248.171 168.480 201.937 1.00 63.61  ? 480 ASN C OD1   1 
ATOM   6504 N ND2   . ASN B 2 477 ? 246.930 169.695 200.527 1.00 63.61  ? 480 ASN C ND2   1 
ATOM   6505 N N     . PHE B 2 478 ? 247.796 172.126 205.487 1.00 62.09  ? 481 PHE C N     1 
ATOM   6506 C CA    . PHE B 2 478 ? 248.047 173.265 206.366 1.00 62.09  ? 481 PHE C CA    1 
ATOM   6507 C C     . PHE B 2 478 ? 249.189 172.967 207.331 1.00 62.09  ? 481 PHE C C     1 
ATOM   6508 O O     . PHE B 2 478 ? 250.096 173.792 207.525 1.00 62.09  ? 481 PHE C O     1 
ATOM   6509 C CB    . PHE B 2 478 ? 246.768 173.614 207.122 1.00 62.09  ? 481 PHE C CB    1 
ATOM   6510 C CG    . PHE B 2 478 ? 246.933 174.710 208.126 1.00 62.09  ? 481 PHE C CG    1 
ATOM   6511 C CD1   . PHE B 2 478 ? 247.621 175.861 207.806 1.00 62.09  ? 481 PHE C CD1   1 
ATOM   6512 C CD2   . PHE B 2 478 ? 246.383 174.595 209.385 1.00 62.09  ? 481 PHE C CD2   1 
ATOM   6513 C CE1   . PHE B 2 478 ? 247.769 176.870 208.729 1.00 62.09  ? 481 PHE C CE1   1 
ATOM   6514 C CE2   . PHE B 2 478 ? 246.525 175.602 210.309 1.00 62.09  ? 481 PHE C CE2   1 
ATOM   6515 C CZ    . PHE B 2 478 ? 247.220 176.740 209.981 1.00 62.09  ? 481 PHE C CZ    1 
ATOM   6516 N N     . THR B 2 479 ? 249.157 171.783 207.948 1.00 63.32  ? 482 THR C N     1 
ATOM   6517 C CA    . THR B 2 479 ? 250.252 171.379 208.826 1.00 63.32  ? 482 THR C CA    1 
ATOM   6518 C C     . THR B 2 479 ? 251.589 171.409 208.094 1.00 63.32  ? 482 THR C C     1 
ATOM   6519 O O     . THR B 2 479 ? 252.596 171.902 208.626 1.00 63.32  ? 482 THR C O     1 
ATOM   6520 C CB    . THR B 2 479 ? 249.986 169.985 209.385 1.00 63.32  ? 482 THR C CB    1 
ATOM   6521 O OG1   . THR B 2 479 ? 248.879 170.041 210.289 1.00 63.32  ? 482 THR C OG1   1 
ATOM   6522 C CG2   . THR B 2 479 ? 251.200 169.468 210.123 1.00 63.32  ? 482 THR C CG2   1 
ATOM   6523 N N     . ASN B 2 480 ? 251.619 170.900 206.866 1.00 64.32  ? 483 ASN C N     1 
ATOM   6524 C CA    . ASN B 2 480 ? 252.887 170.848 206.150 1.00 64.32  ? 483 ASN C CA    1 
ATOM   6525 C C     . ASN B 2 480 ? 253.323 172.218 205.646 1.00 64.32  ? 483 ASN C C     1 
ATOM   6526 O O     . ASN B 2 480 ? 254.525 172.473 205.543 1.00 64.32  ? 483 ASN C O     1 
ATOM   6527 C CB    . ASN B 2 480 ? 252.799 169.842 205.011 1.00 64.32  ? 483 ASN C CB    1 
ATOM   6528 C CG    . ASN B 2 480 ? 253.076 168.433 205.477 1.00 64.32  ? 483 ASN C CG    1 
ATOM   6529 O OD1   . ASN B 2 480 ? 254.227 168.047 205.662 1.00 64.32  ? 483 ASN C OD1   1 
ATOM   6530 N ND2   . ASN B 2 480 ? 252.022 167.663 205.696 1.00 64.32  ? 483 ASN C ND2   1 
ATOM   6531 N N     . GLU B 2 481 ? 252.381 173.114 205.351 1.00 65.38  ? 484 GLU C N     1 
ATOM   6532 C CA    . GLU B 2 481 ? 252.741 174.506 205.104 1.00 65.38  ? 484 GLU C CA    1 
ATOM   6533 C C     . GLU B 2 481 ? 253.441 175.106 206.312 1.00 65.38  ? 484 GLU C C     1 
ATOM   6534 O O     . GLU B 2 481 ? 254.445 175.814 206.172 1.00 65.38  ? 484 GLU C O     1 
ATOM   6535 C CB    . GLU B 2 481 ? 251.496 175.324 204.767 1.00 65.38  ? 484 GLU C CB    1 
ATOM   6536 C CG    . GLU B 2 481 ? 250.874 175.022 203.427 1.00 65.38  ? 484 GLU C CG    1 
ATOM   6537 C CD    . GLU B 2 481 ? 251.704 175.532 202.277 1.00 65.38  ? 484 GLU C CD    1 
ATOM   6538 O OE1   . GLU B 2 481 ? 252.367 176.575 202.439 1.00 65.38  ? 484 GLU C OE1   1 
ATOM   6539 O OE2   . GLU B 2 481 ? 251.691 174.893 201.207 1.00 65.38  ? 484 GLU C OE2   1 
ATOM   6540 N N     . LYS B 2 482 ? 252.920 174.832 207.510 1.00 64.70  ? 485 LYS C N     1 
ATOM   6541 C CA    . LYS B 2 482 ? 253.555 175.345 208.720 1.00 64.70  ? 485 LYS C CA    1 
ATOM   6542 C C     . LYS B 2 482 ? 254.966 174.792 208.872 1.00 64.70  ? 485 LYS C C     1 
ATOM   6543 O O     . LYS B 2 482 ? 255.914 175.535 209.160 1.00 64.70  ? 485 LYS C O     1 
ATOM   6544 C CB    . LYS B 2 482 ? 252.708 175.003 209.944 1.00 64.70  ? 485 LYS C CB    1 
ATOM   6545 C CG    . LYS B 2 482 ? 251.363 175.694 209.973 1.00 64.70  ? 485 LYS C CG    1 
ATOM   6546 C CD    . LYS B 2 482 ? 251.513 177.195 210.083 1.00 64.70  ? 485 LYS C CD    1 
ATOM   6547 C CE    . LYS B 2 482 ? 251.770 177.614 211.514 1.00 64.70  ? 485 LYS C CE    1 
ATOM   6548 N NZ    . LYS B 2 482 ? 250.722 177.095 212.427 1.00 64.70  ? 485 LYS C NZ    1 
ATOM   6549 N N     . LEU B 2 483 ? 255.124 173.482 208.672 1.00 63.43  ? 486 LEU C N     1 
ATOM   6550 C CA    . LEU B 2 483 ? 256.447 172.872 208.805 1.00 63.43  ? 486 LEU C CA    1 
ATOM   6551 C C     . LEU B 2 483 ? 257.429 173.429 207.780 1.00 63.43  ? 486 LEU C C     1 
ATOM   6552 O O     . LEU B 2 483 ? 258.603 173.668 208.095 1.00 63.43  ? 486 LEU C O     1 
ATOM   6553 C CB    . LEU B 2 483 ? 256.344 171.355 208.671 1.00 63.43  ? 486 LEU C CB    1 
ATOM   6554 C CG    . LEU B 2 483 ? 255.736 170.615 209.858 1.00 63.43  ? 486 LEU C CG    1 
ATOM   6555 C CD1   . LEU B 2 483 ? 255.778 169.124 209.615 1.00 63.43  ? 486 LEU C CD1   1 
ATOM   6556 C CD2   . LEU B 2 483 ? 256.470 170.970 211.132 1.00 63.43  ? 486 LEU C CD2   1 
ATOM   6557 N N     . GLN B 2 484 ? 256.973 173.646 206.546 1.00 66.43  ? 487 GLN C N     1 
ATOM   6558 C CA    . GLN B 2 484 ? 257.877 174.155 205.524 1.00 66.43  ? 487 GLN C CA    1 
ATOM   6559 C C     . GLN B 2 484 ? 258.242 175.609 205.782 1.00 66.43  ? 487 GLN C C     1 
ATOM   6560 O O     . GLN B 2 484 ? 259.370 176.022 205.507 1.00 66.43  ? 487 GLN C O     1 
ATOM   6561 C CB    . GLN B 2 484 ? 257.263 173.993 204.138 1.00 66.43  ? 487 GLN C CB    1 
ATOM   6562 C CG    . GLN B 2 484 ? 258.202 174.388 203.016 1.00 66.43  ? 487 GLN C CG    1 
ATOM   6563 C CD    . GLN B 2 484 ? 259.444 173.523 202.969 1.00 66.43  ? 487 GLN C CD    1 
ATOM   6564 O OE1   . GLN B 2 484 ? 259.409 172.348 203.326 1.00 66.43  ? 487 GLN C OE1   1 
ATOM   6565 N NE2   . GLN B 2 484 ? 260.552 174.104 202.534 1.00 66.43  ? 487 GLN C NE2   1 
ATOM   6566 N N     . GLN B 2 485 ? 257.309 176.405 206.307 1.00 68.54  ? 488 GLN C N     1 
ATOM   6567 C CA    . GLN B 2 485 ? 257.670 177.758 206.716 1.00 68.54  ? 488 GLN C CA    1 
ATOM   6568 C C     . GLN B 2 485 ? 258.711 177.725 207.825 1.00 68.54  ? 488 GLN C C     1 
ATOM   6569 O O     . GLN B 2 485 ? 259.639 178.543 207.847 1.00 68.54  ? 488 GLN C O     1 
ATOM   6570 C CB    . GLN B 2 485 ? 256.430 178.523 207.170 1.00 68.54  ? 488 GLN C CB    1 
ATOM   6571 C CG    . GLN B 2 485 ? 256.695 179.982 207.483 1.00 68.54  ? 488 GLN C CG    1 
ATOM   6572 C CD    . GLN B 2 485 ? 255.493 180.676 208.082 1.00 68.54  ? 488 GLN C CD    1 
ATOM   6573 O OE1   . GLN B 2 485 ? 254.888 180.181 209.031 1.00 68.54  ? 488 GLN C OE1   1 
ATOM   6574 N NE2   . GLN B 2 485 ? 255.139 181.828 207.532 1.00 68.54  ? 488 GLN C NE2   1 
ATOM   6575 N N     . PHE B 2 486 ? 258.569 176.779 208.754 1.00 65.55  ? 489 PHE C N     1 
ATOM   6576 C CA    . PHE B 2 486 ? 259.569 176.589 209.800 1.00 65.55  ? 489 PHE C CA    1 
ATOM   6577 C C     . PHE B 2 486 ? 260.946 176.330 209.201 1.00 65.55  ? 489 PHE C C     1 
ATOM   6578 O O     . PHE B 2 486 ? 261.931 176.994 209.554 1.00 65.55  ? 489 PHE C O     1 
ATOM   6579 C CB    . PHE B 2 486 ? 259.127 175.435 210.700 1.00 65.55  ? 489 PHE C CB    1 
ATOM   6580 C CG    . PHE B 2 486 ? 260.110 175.066 211.764 1.00 65.55  ? 489 PHE C CG    1 
ATOM   6581 C CD1   . PHE B 2 486 ? 260.495 175.980 212.721 1.00 65.55  ? 489 PHE C CD1   1 
ATOM   6582 C CD2   . PHE B 2 486 ? 260.618 173.785 211.830 1.00 65.55  ? 489 PHE C CD2   1 
ATOM   6583 C CE1   . PHE B 2 486 ? 261.388 175.630 213.706 1.00 65.55  ? 489 PHE C CE1   1 
ATOM   6584 C CE2   . PHE B 2 486 ? 261.509 173.431 212.813 1.00 65.55  ? 489 PHE C CE2   1 
ATOM   6585 C CZ    . PHE B 2 486 ? 261.894 174.354 213.752 1.00 65.55  ? 489 PHE C CZ    1 
ATOM   6586 N N     . PHE B 2 487 ? 261.026 175.377 208.271 1.00 66.98  ? 490 PHE C N     1 
ATOM   6587 C CA    . PHE B 2 487 ? 262.313 175.059 207.656 1.00 66.98  ? 490 PHE C CA    1 
ATOM   6588 C C     . PHE B 2 487 ? 262.869 176.241 206.874 1.00 66.98  ? 490 PHE C C     1 
ATOM   6589 O O     . PHE B 2 487 ? 264.080 176.493 206.891 1.00 66.98  ? 490 PHE C O     1 
ATOM   6590 C CB    . PHE B 2 487 ? 262.194 173.846 206.739 1.00 66.98  ? 490 PHE C CB    1 
ATOM   6591 C CG    . PHE B 2 487 ? 263.287 173.766 205.716 1.00 66.98  ? 490 PHE C CG    1 
ATOM   6592 C CD1   . PHE B 2 487 ? 264.525 173.253 206.049 1.00 66.98  ? 490 PHE C CD1   1 
ATOM   6593 C CD2   . PHE B 2 487 ? 263.082 174.209 204.425 1.00 66.98  ? 490 PHE C CD2   1 
ATOM   6594 C CE1   . PHE B 2 487 ? 265.536 173.185 205.115 1.00 66.98  ? 490 PHE C CE1   1 
ATOM   6595 C CE2   . PHE B 2 487 ? 264.089 174.142 203.489 1.00 66.98  ? 490 PHE C CE2   1 
ATOM   6596 C CZ    . PHE B 2 487 ? 265.318 173.632 203.837 1.00 66.98  ? 490 PHE C CZ    1 
ATOM   6597 N N     . ASN B 2 488 ? 262.008 176.959 206.155 1.00 71.65  ? 491 ASN C N     1 
ATOM   6598 C CA    . ASN B 2 488 ? 262.473 178.079 205.348 1.00 71.65  ? 491 ASN C CA    1 
ATOM   6599 C C     . ASN B 2 488 ? 263.030 179.193 206.220 1.00 71.65  ? 491 ASN C C     1 
ATOM   6600 O O     . ASN B 2 488 ? 264.052 179.799 205.884 1.00 71.65  ? 491 ASN C O     1 
ATOM   6601 C CB    . ASN B 2 488 ? 261.339 178.598 204.471 1.00 71.65  ? 491 ASN C CB    1 
ATOM   6602 C CG    . ASN B 2 488 ? 261.192 177.819 203.192 1.00 71.65  ? 491 ASN C CG    1 
ATOM   6603 O OD1   . ASN B 2 488 ? 261.543 176.644 203.121 1.00 71.65  ? 491 ASN C OD1   1 
ATOM   6604 N ND2   . ASN B 2 488 ? 260.666 178.469 202.166 1.00 71.65  ? 491 ASN C ND2   1 
ATOM   6605 N N     . HIS B 2 489 ? 262.380 179.476 207.349 1.00 75.22  ? 492 HIS C N     1 
ATOM   6606 C CA    . HIS B 2 489 ? 262.928 180.479 208.256 1.00 75.22  ? 492 HIS C CA    1 
ATOM   6607 C C     . HIS B 2 489 ? 264.238 180.009 208.877 1.00 75.22  ? 492 HIS C C     1 
ATOM   6608 O O     . HIS B 2 489 ? 265.158 180.813 209.084 1.00 75.22  ? 492 HIS C O     1 
ATOM   6609 C CB    . HIS B 2 489 ? 261.921 180.828 209.345 1.00 75.22  ? 492 HIS C CB    1 
ATOM   6610 C CG    . HIS B 2 489 ? 262.497 181.671 210.435 1.00 75.22  ? 492 HIS C CG    1 
ATOM   6611 N ND1   . HIS B 2 489 ? 262.641 183.036 210.320 1.00 75.22  ? 492 HIS C ND1   1 
ATOM   6612 C CD2   . HIS B 2 489 ? 262.982 181.343 211.654 1.00 75.22  ? 492 HIS C CD2   1 
ATOM   6613 C CE1   . HIS B 2 489 ? 263.182 183.514 211.426 1.00 75.22  ? 492 HIS C CE1   1 
ATOM   6614 N NE2   . HIS B 2 489 ? 263.399 182.507 212.252 1.00 75.22  ? 492 HIS C NE2   1 
ATOM   6615 N N     . HIS B 2 490 ? 264.343 178.715 209.187 1.00 73.40  ? 493 HIS C N     1 
ATOM   6616 C CA    . HIS B 2 490 ? 265.603 178.187 209.701 1.00 73.40  ? 493 HIS C CA    1 
ATOM   6617 C C     . HIS B 2 490 ? 266.734 178.393 208.698 1.00 73.40  ? 493 HIS C C     1 
ATOM   6618 O O     . HIS B 2 490 ? 267.835 178.840 209.056 1.00 73.40  ? 493 HIS C O     1 
ATOM   6619 C CB    . HIS B 2 490 ? 265.443 176.708 210.041 1.00 73.40  ? 493 HIS C CB    1 
ATOM   6620 C CG    . HIS B 2 490 ? 266.702 176.059 210.518 1.00 73.40  ? 493 HIS C CG    1 
ATOM   6621 N ND1   . HIS B 2 490 ? 267.450 176.562 211.560 1.00 73.40  ? 493 HIS C ND1   1 
ATOM   6622 C CD2   . HIS B 2 490 ? 267.343 174.944 210.099 1.00 73.40  ? 493 HIS C CD2   1 
ATOM   6623 C CE1   . HIS B 2 490 ? 268.499 175.786 211.760 1.00 73.40  ? 493 HIS C CE1   1 
ATOM   6624 N NE2   . HIS B 2 490 ? 268.457 174.796 210.888 1.00 73.40  ? 493 HIS C NE2   1 
ATOM   6625 N N     . MET B 2 491 ? 266.479 178.071 207.429 1.00 76.43  ? 494 MET C N     1 
ATOM   6626 C CA    . MET B 2 491 ? 267.496 178.278 206.406 1.00 76.43  ? 494 MET C CA    1 
ATOM   6627 C C     . MET B 2 491 ? 267.793 179.758 206.207 1.00 76.43  ? 494 MET C C     1 
ATOM   6628 O O     . MET B 2 491 ? 268.939 180.123 205.937 1.00 76.43  ? 494 MET C O     1 
ATOM   6629 C CB    . MET B 2 491 ? 267.073 177.636 205.086 1.00 76.43  ? 494 MET C CB    1 
ATOM   6630 C CG    . MET B 2 491 ? 267.912 178.072 203.897 1.00 76.43  ? 494 MET C CG    1 
ATOM   6631 S SD    . MET B 2 491 ? 267.607 177.104 202.414 1.00 76.43  ? 494 MET C SD    1 
ATOM   6632 C CE    . MET B 2 491 ? 265.827 176.971 202.480 1.00 76.43  ? 494 MET C CE    1 
ATOM   6633 N N     . PHE B 2 492 ? 266.785 180.620 206.341 1.00 79.95  ? 495 PHE C N     1 
ATOM   6634 C CA    . PHE B 2 492 ? 267.037 182.057 206.311 1.00 79.95  ? 495 PHE C CA    1 
ATOM   6635 C C     . PHE B 2 492 ? 268.038 182.462 207.379 1.00 79.95  ? 495 PHE C C     1 
ATOM   6636 O O     . PHE B 2 492 ? 268.987 183.206 207.105 1.00 79.95  ? 495 PHE C O     1 
ATOM   6637 C CB    . PHE B 2 492 ? 265.732 182.823 206.500 1.00 79.95  ? 495 PHE C CB    1 
ATOM   6638 C CG    . PHE B 2 492 ? 265.924 184.286 206.769 1.00 79.95  ? 495 PHE C CG    1 
ATOM   6639 C CD1   . PHE B 2 492 ? 266.443 185.122 205.799 1.00 79.95  ? 495 PHE C CD1   1 
ATOM   6640 C CD2   . PHE B 2 492 ? 265.580 184.826 207.994 1.00 79.95  ? 495 PHE C CD2   1 
ATOM   6641 C CE1   . PHE B 2 492 ? 266.615 186.465 206.046 1.00 79.95  ? 495 PHE C CE1   1 
ATOM   6642 C CE2   . PHE B 2 492 ? 265.749 186.169 208.244 1.00 79.95  ? 495 PHE C CE2   1 
ATOM   6643 C CZ    . PHE B 2 492 ? 266.268 186.988 207.269 1.00 79.95  ? 495 PHE C CZ    1 
ATOM   6644 N N     . VAL B 2 493 ? 267.840 181.981 208.606 1.00 79.20  ? 496 VAL C N     1 
ATOM   6645 C CA    . VAL B 2 493 ? 268.762 182.315 209.688 1.00 79.20  ? 496 VAL C CA    1 
ATOM   6646 C C     . VAL B 2 493 ? 270.167 181.814 209.373 1.00 79.20  ? 496 VAL C C     1 
ATOM   6647 O O     . VAL B 2 493 ? 271.152 182.550 209.522 1.00 79.20  ? 496 VAL C O     1 
ATOM   6648 C CB    . VAL B 2 493 ? 268.247 181.754 211.025 1.00 79.20  ? 496 VAL C CB    1 
ATOM   6649 C CG1   . VAL B 2 493 ? 269.283 181.953 212.108 1.00 79.20  ? 496 VAL C CG1   1 
ATOM   6650 C CG2   . VAL B 2 493 ? 266.951 182.433 211.411 1.00 79.20  ? 496 VAL C CG2   1 
ATOM   6651 N N     . LEU B 2 494 ? 270.286 180.557 208.933 1.00 80.94  ? 497 LEU C N     1 
ATOM   6652 C CA    . LEU B 2 494 ? 271.616 180.010 208.663 1.00 80.94  ? 497 LEU C CA    1 
ATOM   6653 C C     . LEU B 2 494 ? 272.318 180.755 207.532 1.00 80.94  ? 497 LEU C C     1 
ATOM   6654 O O     . LEU B 2 494 ? 273.527 181.003 207.603 1.00 80.94  ? 497 LEU C O     1 
ATOM   6655 C CB    . LEU B 2 494 ? 271.536 178.519 208.345 1.00 80.94  ? 497 LEU C CB    1 
ATOM   6656 C CG    . LEU B 2 494 ? 271.208 177.604 209.521 1.00 80.94  ? 497 LEU C CG    1 
ATOM   6657 C CD1   . LEU B 2 494 ? 271.124 176.166 209.058 1.00 80.94  ? 497 LEU C CD1   1 
ATOM   6658 C CD2   . LEU B 2 494 ? 272.248 177.755 210.610 1.00 80.94  ? 497 LEU C CD2   1 
ATOM   6659 N N     . GLU B 2 495 ? 271.585 181.111 206.476 1.00 86.92  ? 498 GLU C N     1 
ATOM   6660 C CA    . GLU B 2 495 ? 272.195 181.865 205.386 1.00 86.92  ? 498 GLU C CA    1 
ATOM   6661 C C     . GLU B 2 495 ? 272.622 183.248 205.851 1.00 86.92  ? 498 GLU C C     1 
ATOM   6662 O O     . GLU B 2 495 ? 273.684 183.740 205.455 1.00 86.92  ? 498 GLU C O     1 
ATOM   6663 C CB    . GLU B 2 495 ? 271.234 181.972 204.205 1.00 86.92  ? 498 GLU C CB    1 
ATOM   6664 C CG    . GLU B 2 495 ? 270.877 180.644 203.580 1.00 86.92  ? 498 GLU C CG    1 
ATOM   6665 C CD    . GLU B 2 495 ? 272.096 179.842 203.197 1.00 86.92  ? 498 GLU C CD    1 
ATOM   6666 O OE1   . GLU B 2 495 ? 272.836 180.282 202.295 1.00 86.92  ? 498 GLU C OE1   1 
ATOM   6667 O OE2   . GLU B 2 495 ? 272.316 178.771 203.801 1.00 86.92  ? 498 GLU C OE2   1 
ATOM   6668 N N     . GLN B 2 496 ? 271.804 183.895 206.683 1.00 87.87  ? 499 GLN C N     1 
ATOM   6669 C CA    . GLN B 2 496 ? 272.205 185.173 207.256 1.00 87.87  ? 499 GLN C CA    1 
ATOM   6670 C C     . GLN B 2 496 ? 273.518 185.042 208.018 1.00 87.87  ? 499 GLN C C     1 
ATOM   6671 O O     . GLN B 2 496 ? 274.424 185.870 207.859 1.00 87.87  ? 499 GLN C O     1 
ATOM   6672 C CB    . GLN B 2 496 ? 271.097 185.700 208.166 1.00 87.87  ? 499 GLN C CB    1 
ATOM   6673 C CG    . GLN B 2 496 ? 271.343 187.088 208.712 1.00 87.87  ? 499 GLN C CG    1 
ATOM   6674 C CD    . GLN B 2 496 ? 271.450 188.123 207.614 1.00 87.87  ? 499 GLN C CD    1 
ATOM   6675 O OE1   . GLN B 2 496 ? 272.538 188.612 207.310 1.00 87.87  ? 499 GLN C OE1   1 
ATOM   6676 N NE2   . GLN B 2 496 ? 270.319 188.458 207.005 1.00 87.87  ? 499 GLN C NE2   1 
ATOM   6677 N N     . GLU B 2 497 ? 273.647 183.995 208.836 1.00 89.04  ? 500 GLU C N     1 
ATOM   6678 C CA    . GLU B 2 497 ? 274.870 183.831 209.617 1.00 89.04  ? 500 GLU C CA    1 
ATOM   6679 C C     . GLU B 2 497 ? 276.070 183.542 208.723 1.00 89.04  ? 500 GLU C C     1 
ATOM   6680 O O     . GLU B 2 497 ? 277.167 184.055 208.966 1.00 89.04  ? 500 GLU C O     1 
ATOM   6681 C CB    . GLU B 2 497 ? 274.706 182.723 210.658 1.00 89.04  ? 500 GLU C CB    1 
ATOM   6682 C CG    . GLU B 2 497 ? 273.462 182.838 211.522 1.00 89.04  ? 500 GLU C CG    1 
ATOM   6683 C CD    . GLU B 2 497 ? 273.325 184.193 212.189 1.00 89.04  ? 500 GLU C CD    1 
ATOM   6684 O OE1   . GLU B 2 497 ? 273.981 184.417 213.227 1.00 89.04  ? 500 GLU C OE1   1 
ATOM   6685 O OE2   . GLU B 2 497 ? 272.554 185.031 211.677 1.00 89.04  ? 500 GLU C OE2   1 
ATOM   6686 N N     . GLU B 2 498 ? 275.886 182.723 207.683 1.00 90.80  ? 501 GLU C N     1 
ATOM   6687 C CA    . GLU B 2 498 ? 277.017 182.386 206.820 1.00 90.80  ? 501 GLU C CA    1 
ATOM   6688 C C     . GLU B 2 498 ? 277.410 183.548 205.917 1.00 90.80  ? 501 GLU C C     1 
ATOM   6689 O O     . GLU B 2 498 ? 278.553 183.609 205.453 1.00 90.80  ? 501 GLU C O     1 
ATOM   6690 C CB    . GLU B 2 498 ? 276.706 181.151 205.978 1.00 90.80  ? 501 GLU C CB    1 
ATOM   6691 C CG    . GLU B 2 498 ? 277.056 179.841 206.659 1.00 90.80  ? 501 GLU C CG    1 
ATOM   6692 C CD    . GLU B 2 498 ? 277.198 178.696 205.679 1.00 90.80  ? 501 GLU C CD    1 
ATOM   6693 O OE1   . GLU B 2 498 ? 277.988 178.829 204.721 1.00 90.80  ? 501 GLU C OE1   1 
ATOM   6694 O OE2   . GLU B 2 498 ? 276.521 177.664 205.864 1.00 90.80  ? 501 GLU C OE2   1 
ATOM   6695 N N     . TYR B 2 499 ? 276.486 184.468 205.646 1.00 91.53  ? 502 TYR C N     1 
ATOM   6696 C CA    . TYR B 2 499 ? 276.852 185.671 204.909 1.00 91.53  ? 502 TYR C CA    1 
ATOM   6697 C C     . TYR B 2 499 ? 277.564 186.668 205.812 1.00 91.53  ? 502 TYR C C     1 
ATOM   6698 O O     . TYR B 2 499 ? 278.537 187.307 205.396 1.00 91.53  ? 502 TYR C O     1 
ATOM   6699 C CB    . TYR B 2 499 ? 275.613 186.306 204.279 1.00 91.53  ? 502 TYR C CB    1 
ATOM   6700 C CG    . TYR B 2 499 ? 275.201 185.696 202.958 1.00 91.53  ? 502 TYR C CG    1 
ATOM   6701 C CD1   . TYR B 2 499 ? 275.223 184.324 202.764 1.00 91.53  ? 502 TYR C CD1   1 
ATOM   6702 C CD2   . TYR B 2 499 ? 274.783 186.496 201.907 1.00 91.53  ? 502 TYR C CD2   1 
ATOM   6703 C CE1   . TYR B 2 499 ? 274.844 183.767 201.561 1.00 91.53  ? 502 TYR C CE1   1 
ATOM   6704 C CE2   . TYR B 2 499 ? 274.403 185.949 200.701 1.00 91.53  ? 502 TYR C CE2   1 
ATOM   6705 C CZ    . TYR B 2 499 ? 274.435 184.584 200.533 1.00 91.53  ? 502 TYR C CZ    1 
ATOM   6706 O OH    . TYR B 2 499 ? 274.055 184.034 199.332 1.00 91.53  ? 502 TYR C OH    1 
ATOM   6707 N N     . LYS B 2 500 ? 277.092 186.819 207.053 1.00 93.93  ? 503 LYS C N     1 
ATOM   6708 C CA    . LYS B 2 500 ? 277.748 187.734 207.980 1.00 93.93  ? 503 LYS C CA    1 
ATOM   6709 C C     . LYS B 2 500 ? 279.137 187.241 208.370 1.00 93.93  ? 503 LYS C C     1 
ATOM   6710 O O     . LYS B 2 500 ? 280.045 188.053 208.582 1.00 93.93  ? 503 LYS C O     1 
ATOM   6711 C CB    . LYS B 2 500 ? 276.878 187.929 209.221 1.00 93.93  ? 503 LYS C CB    1 
ATOM   6712 C CG    . LYS B 2 500 ? 277.547 188.696 210.347 1.00 93.93  ? 503 LYS C CG    1 
ATOM   6713 C CD    . LYS B 2 500 ? 276.657 188.750 211.577 1.00 93.93  ? 503 LYS C CD    1 
ATOM   6714 C CE    . LYS B 2 500 ? 277.264 189.626 212.660 1.00 93.93  ? 503 LYS C CE    1 
ATOM   6715 N NZ    . LYS B 2 500 ? 277.190 191.069 212.312 1.00 93.93  ? 503 LYS C NZ    1 
ATOM   6716 N N     . LYS B 2 501 ? 279.326 185.922 208.455 1.00 94.40  ? 504 LYS C N     1 
ATOM   6717 C CA    . LYS B 2 501 ? 280.637 185.384 208.802 1.00 94.40  ? 504 LYS C CA    1 
ATOM   6718 C C     . LYS B 2 501 ? 281.665 185.677 207.716 1.00 94.40  ? 504 LYS C C     1 
ATOM   6719 O O     . LYS B 2 501 ? 282.810 186.034 208.017 1.00 94.40  ? 504 LYS C O     1 
ATOM   6720 C CB    . LYS B 2 501 ? 280.536 183.880 209.049 1.00 94.40  ? 504 LYS C CB    1 
ATOM   6721 C CG    . LYS B 2 501 ? 281.876 183.174 209.160 1.00 94.40  ? 504 LYS C CG    1 
ATOM   6722 C CD    . LYS B 2 501 ? 281.716 181.663 209.150 1.00 94.40  ? 504 LYS C CD    1 
ATOM   6723 C CE    . LYS B 2 501 ? 280.558 181.212 210.026 1.00 94.40  ? 504 LYS C CE    1 
ATOM   6724 N NZ    . LYS B 2 501 ? 280.700 181.672 211.435 1.00 94.40  ? 504 LYS C NZ    1 
ATOM   6725 N N     . GLU B 2 502 ? 281.279 185.533 206.451 1.00 98.65  ? 505 GLU C N     1 
ATOM   6726 C CA    . GLU B 2 502 ? 282.166 185.812 205.330 1.00 98.65  ? 505 GLU C CA    1 
ATOM   6727 C C     . GLU B 2 502 ? 282.181 187.284 204.945 1.00 98.65  ? 505 GLU C C     1 
ATOM   6728 O O     . GLU B 2 502 ? 282.827 187.646 203.958 1.00 98.65  ? 505 GLU C O     1 
ATOM   6729 C CB    . GLU B 2 502 ? 281.770 184.966 204.119 1.00 98.65  ? 505 GLU C CB    1 
ATOM   6730 C CG    . GLU B 2 502 ? 281.833 183.470 204.361 1.00 98.65  ? 505 GLU C CG    1 
ATOM   6731 C CD    . GLU B 2 502 ? 283.248 182.938 204.340 1.00 98.65  ? 505 GLU C CD    1 
ATOM   6732 O OE1   . GLU B 2 502 ? 284.146 183.665 203.873 1.00 98.65  ? 505 GLU C OE1   1 
ATOM   6733 O OE2   . GLU B 2 502 ? 283.465 181.796 204.793 1.00 98.65  ? 505 GLU C OE2   1 
ATOM   6734 N N     . GLY B 2 503 ? 281.484 188.134 205.693 1.00 99.17  ? 506 GLY C N     1 
ATOM   6735 C CA    . GLY B 2 503 ? 281.477 189.558 205.424 1.00 99.17  ? 506 GLY C CA    1 
ATOM   6736 C C     . GLY B 2 503 ? 280.808 189.950 204.123 1.00 99.17  ? 506 GLY C C     1 
ATOM   6737 O O     . GLY B 2 503 ? 280.986 191.075 203.646 1.00 99.17  ? 506 GLY C O     1 
ATOM   6738 N N     . ILE B 2 504 ? 280.038 189.038 203.537 1.00 100.60 ? 507 ILE C N     1 
ATOM   6739 C CA    . ILE B 2 504 ? 279.326 189.336 202.298 1.00 100.60 ? 507 ILE C CA    1 
ATOM   6740 C C     . ILE B 2 504 ? 278.185 190.288 202.635 1.00 100.60 ? 507 ILE C C     1 
ATOM   6741 O O     . ILE B 2 504 ? 277.178 189.881 203.220 1.00 100.60 ? 507 ILE C O     1 
ATOM   6742 C CB    . ILE B 2 504 ? 278.805 188.063 201.624 1.00 100.60 ? 507 ILE C CB    1 
ATOM   6743 C CG1   . ILE B 2 504 ? 279.971 187.204 201.135 1.00 100.60 ? 507 ILE C CG1   1 
ATOM   6744 C CG2   . ILE B 2 504 ? 277.892 188.413 200.464 1.00 100.60 ? 507 ILE C CG2   1 
ATOM   6745 C CD1   . ILE B 2 504 ? 280.793 187.857 200.055 1.00 100.60 ? 507 ILE C CD1   1 
ATOM   6746 N N     . GLU B 2 505 ? 278.340 191.559 202.275 1.00 105.63 ? 508 GLU C N     1 
ATOM   6747 C CA    . GLU B 2 505 ? 277.325 192.563 202.579 1.00 105.63 ? 508 GLU C CA    1 
ATOM   6748 C C     . GLU B 2 505 ? 276.204 192.433 201.558 1.00 105.63 ? 508 GLU C C     1 
ATOM   6749 O O     . GLU B 2 505 ? 276.277 192.981 200.456 1.00 105.63 ? 508 GLU C O     1 
ATOM   6750 C CB    . GLU B 2 505 ? 277.926 193.963 202.580 1.00 105.63 ? 508 GLU C CB    1 
ATOM   6751 C CG    . GLU B 2 505 ? 276.938 195.035 202.992 1.00 105.63 ? 508 GLU C CG    1 
ATOM   6752 C CD    . GLU B 2 505 ? 276.453 194.852 204.418 1.00 105.63 ? 508 GLU C CD    1 
ATOM   6753 O OE1   . GLU B 2 505 ? 277.208 194.289 205.240 1.00 105.63 ? 508 GLU C OE1   1 
ATOM   6754 O OE2   . GLU B 2 505 ? 275.309 195.257 204.713 1.00 105.63 ? 508 GLU C OE2   1 
ATOM   6755 N N     . TRP B 2 506 ? 275.158 191.702 201.933 1.00 102.60 ? 509 TRP C N     1 
ATOM   6756 C CA    . TRP B 2 506 ? 274.045 191.426 201.032 1.00 102.60 ? 509 TRP C CA    1 
ATOM   6757 C C     . TRP B 2 506 ? 272.853 191.047 201.897 1.00 102.60 ? 509 TRP C C     1 
ATOM   6758 O O     . TRP B 2 506 ? 272.889 190.015 202.574 1.00 102.60 ? 509 TRP C O     1 
ATOM   6759 C CB    . TRP B 2 506 ? 274.408 190.310 200.059 1.00 102.60 ? 509 TRP C CB    1 
ATOM   6760 C CG    . TRP B 2 506 ? 273.254 189.743 199.301 1.00 102.60 ? 509 TRP C CG    1 
ATOM   6761 C CD1   . TRP B 2 506 ? 272.570 188.600 199.585 1.00 102.60 ? 509 TRP C CD1   1 
ATOM   6762 C CD2   . TRP B 2 506 ? 272.664 190.279 198.112 1.00 102.60 ? 509 TRP C CD2   1 
ATOM   6763 N NE1   . TRP B 2 506 ? 271.580 188.396 198.656 1.00 102.60 ? 509 TRP C NE1   1 
ATOM   6764 C CE2   . TRP B 2 506 ? 271.617 189.414 197.740 1.00 102.60 ? 509 TRP C CE2   1 
ATOM   6765 C CE3   . TRP B 2 506 ? 272.914 191.412 197.331 1.00 102.60 ? 509 TRP C CE3   1 
ATOM   6766 C CZ2   . TRP B 2 506 ? 270.820 189.644 196.622 1.00 102.60 ? 509 TRP C CZ2   1 
ATOM   6767 C CZ3   . TRP B 2 506 ? 272.124 191.638 196.222 1.00 102.60 ? 509 TRP C CZ3   1 
ATOM   6768 C CH2   . TRP B 2 506 ? 271.089 190.759 195.877 1.00 102.60 ? 509 TRP C CH2   1 
ATOM   6769 N N     . GLU B 2 507 ? 271.810 191.871 201.879 1.00 99.90  ? 510 GLU C N     1 
ATOM   6770 C CA    . GLU B 2 507 ? 270.624 191.638 202.688 1.00 99.90  ? 510 GLU C CA    1 
ATOM   6771 C C     . GLU B 2 507 ? 269.434 191.361 201.785 1.00 99.90  ? 510 GLU C C     1 
ATOM   6772 O O     . GLU B 2 507 ? 269.313 191.937 200.700 1.00 99.90  ? 510 GLU C O     1 
ATOM   6773 C CB    . GLU B 2 507 ? 270.323 192.824 203.605 1.00 99.90  ? 510 GLU C CB    1 
ATOM   6774 C CG    . GLU B 2 507 ? 269.545 192.439 204.856 1.00 99.90  ? 510 GLU C CG    1 
ATOM   6775 C CD    . GLU B 2 507 ? 269.838 193.342 206.038 1.00 99.90  ? 510 GLU C CD    1 
ATOM   6776 O OE1   . GLU B 2 507 ? 270.147 194.532 205.820 1.00 99.90  ? 510 GLU C OE1   1 
ATOM   6777 O OE2   . GLU B 2 507 ? 269.760 192.860 207.188 1.00 99.90  ? 510 GLU C OE2   1 
ATOM   6778 N N     . PHE B 2 508 ? 268.560 190.472 202.245 1.00 92.81  ? 511 PHE C N     1 
ATOM   6779 C CA    . PHE B 2 508 ? 267.420 190.027 201.463 1.00 92.81  ? 511 PHE C CA    1 
ATOM   6780 C C     . PHE B 2 508 ? 266.252 189.753 202.397 1.00 92.81  ? 511 PHE C C     1 
ATOM   6781 O O     . PHE B 2 508 ? 266.430 189.498 203.590 1.00 92.81  ? 511 PHE C O     1 
ATOM   6782 C CB    . PHE B 2 508 ? 267.778 188.794 200.623 1.00 92.81  ? 511 PHE C CB    1 
ATOM   6783 C CG    . PHE B 2 508 ? 268.387 187.674 201.415 1.00 92.81  ? 511 PHE C CG    1 
ATOM   6784 C CD1   . PHE B 2 508 ? 269.759 187.591 201.572 1.00 92.81  ? 511 PHE C CD1   1 
ATOM   6785 C CD2   . PHE B 2 508 ? 267.596 186.706 202.003 1.00 92.81  ? 511 PHE C CD2   1 
ATOM   6786 C CE1   . PHE B 2 508 ? 270.329 186.569 202.301 1.00 92.81  ? 511 PHE C CE1   1 
ATOM   6787 C CE2   . PHE B 2 508 ? 268.165 185.681 202.735 1.00 92.81  ? 511 PHE C CE2   1 
ATOM   6788 C CZ    . PHE B 2 508 ? 269.531 185.611 202.881 1.00 92.81  ? 511 PHE C CZ    1 
ATOM   6789 N N     . ILE B 2 509 ? 265.046 189.821 201.830 1.00 90.11  ? 512 ILE C N     1 
ATOM   6790 C CA    . ILE B 2 509 ? 263.835 189.639 202.616 1.00 90.11  ? 512 ILE C CA    1 
ATOM   6791 C C     . ILE B 2 509 ? 263.800 188.221 203.187 1.00 90.11  ? 512 ILE C C     1 
ATOM   6792 O O     . ILE B 2 509 ? 264.410 187.292 202.644 1.00 90.11  ? 512 ILE C O     1 
ATOM   6793 C CB    . ILE B 2 509 ? 262.603 189.937 201.743 1.00 90.11  ? 512 ILE C CB    1 
ATOM   6794 C CG1   . ILE B 2 509 ? 261.308 189.847 202.546 1.00 90.11  ? 512 ILE C CG1   1 
ATOM   6795 C CG2   . ILE B 2 509 ? 262.551 188.991 200.555 1.00 90.11  ? 512 ILE C CG2   1 
ATOM   6796 C CD1   . ILE B 2 509 ? 260.087 190.274 201.771 1.00 90.11  ? 512 ILE C CD1   1 
ATOM   6797 N N     . ASP B 2 510 ? 263.090 188.061 204.304 1.00 86.46  ? 513 ASP C N     1 
ATOM   6798 C CA    . ASP B 2 510 ? 263.053 186.793 205.025 1.00 86.46  ? 513 ASP C CA    1 
ATOM   6799 C C     . ASP B 2 510 ? 262.565 185.666 204.125 1.00 86.46  ? 513 ASP C C     1 
ATOM   6800 O O     . ASP B 2 510 ? 261.523 185.782 203.475 1.00 86.46  ? 513 ASP C O     1 
ATOM   6801 C CB    . ASP B 2 510 ? 262.149 186.926 206.249 1.00 86.46  ? 513 ASP C CB    1 
ATOM   6802 C CG    . ASP B 2 510 ? 262.138 185.680 207.113 1.00 86.46  ? 513 ASP C CG    1 
ATOM   6803 O OD1   . ASP B 2 510 ? 261.673 184.620 206.647 1.00 86.46  ? 513 ASP C OD1   1 
ATOM   6804 O OD2   . ASP B 2 510 ? 262.588 185.764 208.273 1.00 86.46  ? 513 ASP C OD2   1 
ATOM   6805 N N     . PHE B 2 511 ? 263.326 184.571 204.099 1.00 82.74  ? 514 PHE C N     1 
ATOM   6806 C CA    . PHE B 2 511 ? 262.979 183.419 203.275 1.00 82.74  ? 514 PHE C CA    1 
ATOM   6807 C C     . PHE B 2 511 ? 261.643 182.802 203.653 1.00 82.74  ? 514 PHE C C     1 
ATOM   6808 O O     . PHE B 2 511 ? 260.834 182.514 202.766 1.00 82.74  ? 514 PHE C O     1 
ATOM   6809 C CB    . PHE B 2 511 ? 264.065 182.352 203.386 1.00 82.74  ? 514 PHE C CB    1 
ATOM   6810 C CG    . PHE B 2 511 ? 265.255 182.603 202.519 1.00 82.74  ? 514 PHE C CG    1 
ATOM   6811 C CD1   . PHE B 2 511 ? 265.155 183.402 201.400 1.00 82.74  ? 514 PHE C CD1   1 
ATOM   6812 C CD2   . PHE B 2 511 ? 266.478 182.041 202.826 1.00 82.74  ? 514 PHE C CD2   1 
ATOM   6813 C CE1   . PHE B 2 511 ? 266.250 183.627 200.600 1.00 82.74  ? 514 PHE C CE1   1 
ATOM   6814 C CE2   . PHE B 2 511 ? 267.574 182.264 202.032 1.00 82.74  ? 514 PHE C CE2   1 
ATOM   6815 C CZ    . PHE B 2 511 ? 267.461 183.056 200.915 1.00 82.74  ? 514 PHE C CZ    1 
ATOM   6816 N N     . GLY B 2 512 ? 261.389 182.594 204.939 1.00 82.10  ? 515 GLY C N     1 
ATOM   6817 C CA    . GLY B 2 512 ? 260.295 181.730 205.329 1.00 82.10  ? 515 GLY C CA    1 
ATOM   6818 C C     . GLY B 2 512 ? 258.930 182.370 205.407 1.00 82.10  ? 515 GLY C C     1 
ATOM   6819 O O     . GLY B 2 512 ? 258.020 181.987 204.667 1.00 82.10  ? 515 GLY C O     1 
ATOM   6820 N N     . MET B 2 513 ? 258.773 183.360 206.278 1.00 87.31  ? 516 MET C N     1 
ATOM   6821 C CA    . MET B 2 513 ? 257.457 183.934 206.511 1.00 87.31  ? 516 MET C CA    1 
ATOM   6822 C C     . MET B 2 513 ? 256.965 184.776 205.351 1.00 87.31  ? 516 MET C C     1 
ATOM   6823 O O     . MET B 2 513 ? 255.793 184.679 204.986 1.00 87.31  ? 516 MET C O     1 
ATOM   6824 C CB    . MET B 2 513 ? 257.457 184.791 207.782 1.00 87.31  ? 516 MET C CB    1 
ATOM   6825 C CG    . MET B 2 513 ? 257.404 183.996 209.075 1.00 87.31  ? 516 MET C CG    1 
ATOM   6826 S SD    . MET B 2 513 ? 258.983 183.240 209.493 1.00 87.31  ? 516 MET C SD    1 
ATOM   6827 C CE    . MET B 2 513 ? 259.898 184.691 210.003 1.00 87.31  ? 516 MET C CE    1 
ATOM   6828 N N     . ASP B 2 514 ? 257.835 185.562 204.733 1.00 88.14  ? 517 ASP C N     1 
ATOM   6829 C CA    . ASP B 2 514 ? 257.373 186.441 203.674 1.00 88.14  ? 517 ASP C CA    1 
ATOM   6830 C C     . ASP B 2 514 ? 257.147 185.713 202.357 1.00 88.14  ? 517 ASP C C     1 
ATOM   6831 O O     . ASP B 2 514 ? 256.947 186.376 201.333 1.00 88.14  ? 517 ASP C O     1 
ATOM   6832 C CB    . ASP B 2 514 ? 258.370 187.585 203.503 1.00 88.14  ? 517 ASP C CB    1 
ATOM   6833 C CG    . ASP B 2 514 ? 258.409 188.497 204.715 1.00 88.14  ? 517 ASP C CG    1 
ATOM   6834 O OD1   . ASP B 2 514 ? 257.370 188.615 205.396 1.00 88.14  ? 517 ASP C OD1   1 
ATOM   6835 O OD2   . ASP B 2 514 ? 259.472 189.086 204.996 1.00 88.14  ? 517 ASP C OD2   1 
ATOM   6836 N N     . LEU B 2 515 ? 257.168 184.380 202.352 1.00 81.16  ? 518 LEU C N     1 
ATOM   6837 C CA    . LEU B 2 515 ? 256.866 183.593 201.164 1.00 81.16  ? 518 LEU C CA    1 
ATOM   6838 C C     . LEU B 2 515 ? 255.692 182.644 201.361 1.00 81.16  ? 518 LEU C C     1 
ATOM   6839 O O     . LEU B 2 515 ? 254.795 182.596 200.515 1.00 81.16  ? 518 LEU C O     1 
ATOM   6840 C CB    . LEU B 2 515 ? 258.107 182.807 200.718 1.00 81.16  ? 518 LEU C CB    1 
ATOM   6841 C CG    . LEU B 2 515 ? 258.983 183.461 199.641 1.00 81.16  ? 518 LEU C CG    1 
ATOM   6842 C CD1   . LEU B 2 515 ? 259.463 184.848 200.046 1.00 81.16  ? 518 LEU C CD1   1 
ATOM   6843 C CD2   . LEU B 2 515 ? 260.166 182.579 199.299 1.00 81.16  ? 518 LEU C CD2   1 
ATOM   6844 N N     . GLN B 2 516 ? 255.665 181.883 202.457 1.00 75.58  ? 519 GLN C N     1 
ATOM   6845 C CA    . GLN B 2 516 ? 254.531 181.007 202.733 1.00 75.58  ? 519 GLN C CA    1 
ATOM   6846 C C     . GLN B 2 516 ? 253.472 181.641 203.622 1.00 75.58  ? 519 GLN C C     1 
ATOM   6847 O O     . GLN B 2 516 ? 252.377 181.082 203.739 1.00 75.58  ? 519 GLN C O     1 
ATOM   6848 C CB    . GLN B 2 516 ? 254.987 179.694 203.381 1.00 75.58  ? 519 GLN C CB    1 
ATOM   6849 C CG    . GLN B 2 516 ? 255.641 178.700 202.440 1.00 75.58  ? 519 GLN C CG    1 
ATOM   6850 C CD    . GLN B 2 516 ? 257.115 178.955 202.250 1.00 75.58  ? 519 GLN C CD    1 
ATOM   6851 O OE1   . GLN B 2 516 ? 257.740 179.653 203.044 1.00 75.58  ? 519 GLN C OE1   1 
ATOM   6852 N NE2   . GLN B 2 516 ? 257.682 178.391 201.193 1.00 75.58  ? 519 GLN C NE2   1 
ATOM   6853 N N     . ALA B 2 517 ? 253.757 182.782 204.253 1.00 76.31  ? 520 ALA C N     1 
ATOM   6854 C CA    . ALA B 2 517 ? 252.765 183.414 205.113 1.00 76.31  ? 520 ALA C CA    1 
ATOM   6855 C C     . ALA B 2 517 ? 251.544 183.872 204.335 1.00 76.31  ? 520 ALA C C     1 
ATOM   6856 O O     . ALA B 2 517 ? 250.486 184.085 204.935 1.00 76.31  ? 520 ALA C O     1 
ATOM   6857 C CB    . ALA B 2 517 ? 253.384 184.598 205.855 1.00 76.31  ? 520 ALA C CB    1 
ATOM   6858 N N     . CYS B 2 518 ? 251.661 184.020 203.018 1.00 76.56  ? 521 CYS C N     1 
ATOM   6859 C CA    . CYS B 2 518 ? 250.515 184.385 202.201 1.00 76.56  ? 521 CYS C CA    1 
ATOM   6860 C C     . CYS B 2 518 ? 249.591 183.206 201.943 1.00 76.56  ? 521 CYS C C     1 
ATOM   6861 O O     . CYS B 2 518 ? 248.389 183.409 201.751 1.00 76.56  ? 521 CYS C O     1 
ATOM   6862 C CB    . CYS B 2 518 ? 250.987 184.978 200.873 1.00 76.56  ? 521 CYS C CB    1 
ATOM   6863 S SG    . CYS B 2 518 ? 252.414 186.079 201.019 1.00 76.56  ? 521 CYS C SG    1 
ATOM   6864 N N     . ILE B 2 519 ? 250.121 181.978 201.940 1.00 71.76  ? 522 ILE C N     1 
ATOM   6865 C CA    . ILE B 2 519 ? 249.285 180.790 201.779 1.00 71.76  ? 522 ILE C CA    1 
ATOM   6866 C C     . ILE B 2 519 ? 248.667 180.356 203.097 1.00 71.76  ? 522 ILE C C     1 
ATOM   6867 O O     . ILE B 2 519 ? 247.985 179.325 203.148 1.00 71.76  ? 522 ILE C O     1 
ATOM   6868 C CB    . ILE B 2 519 ? 250.109 179.646 201.157 1.00 71.76  ? 522 ILE C CB    1 
ATOM   6869 C CG1   . ILE B 2 519 ? 250.989 180.186 200.033 1.00 71.76  ? 522 ILE C CG1   1 
ATOM   6870 C CG2   . ILE B 2 519 ? 249.202 178.586 200.558 1.00 71.76  ? 522 ILE C CG2   1 
ATOM   6871 C CD1   . ILE B 2 519 ? 252.332 179.495 199.922 1.00 71.76  ? 522 ILE C CD1   1 
ATOM   6872 N N     . ASP B 2 520 ? 248.858 181.128 204.163 1.00 70.34  ? 523 ASP C N     1 
ATOM   6873 C CA    . ASP B 2 520 ? 248.185 180.898 205.438 1.00 70.34  ? 523 ASP C CA    1 
ATOM   6874 C C     . ASP B 2 520 ? 246.958 181.787 205.577 1.00 70.34  ? 523 ASP C C     1 
ATOM   6875 O O     . ASP B 2 520 ? 246.645 182.290 206.659 1.00 70.34  ? 523 ASP C O     1 
ATOM   6876 C CB    . ASP B 2 520 ? 249.146 181.102 206.603 1.00 70.34  ? 523 ASP C CB    1 
ATOM   6877 C CG    . ASP B 2 520 ? 250.289 180.108 206.588 1.00 70.34  ? 523 ASP C CG    1 
ATOM   6878 O OD1   . ASP B 2 520 ? 250.367 179.311 205.633 1.00 70.34  ? 523 ASP C OD1   1 
ATOM   6879 O OD2   . ASP B 2 520 ? 251.106 180.116 207.529 1.00 70.34  ? 523 ASP C OD2   1 
ATOM   6880 N N     . LEU B 2 521 ? 246.273 182.020 204.453 1.00 68.78  ? 524 LEU C N     1 
ATOM   6881 C CA    . LEU B 2 521 ? 244.889 182.473 204.494 1.00 68.78  ? 524 LEU C CA    1 
ATOM   6882 C C     . LEU B 2 521 ? 244.060 181.572 205.391 1.00 68.78  ? 524 LEU C C     1 
ATOM   6883 O O     . LEU B 2 521 ? 243.150 182.037 206.084 1.00 68.78  ? 524 LEU C O     1 
ATOM   6884 C CB    . LEU B 2 521 ? 244.295 182.464 203.087 1.00 68.78  ? 524 LEU C CB    1 
ATOM   6885 C CG    . LEU B 2 521 ? 244.899 183.365 202.020 1.00 68.78  ? 524 LEU C CG    1 
ATOM   6886 C CD1   . LEU B 2 521 ? 244.275 183.033 200.682 1.00 68.78  ? 524 LEU C CD1   1 
ATOM   6887 C CD2   . LEU B 2 521 ? 244.681 184.824 202.374 1.00 68.78  ? 524 LEU C CD2   1 
ATOM   6888 N N     . ILE B 2 522 ? 244.372 180.274 205.386 1.00 64.56  ? 525 ILE C N     1 
ATOM   6889 C CA    . ILE B 2 522 ? 243.597 179.256 206.090 1.00 64.56  ? 525 ILE C CA    1 
ATOM   6890 C C     . ILE B 2 522 ? 243.338 179.625 207.544 1.00 64.56  ? 525 ILE C C     1 
ATOM   6891 O O     . ILE B 2 522 ? 242.237 179.402 208.059 1.00 64.56  ? 525 ILE C O     1 
ATOM   6892 C CB    . ILE B 2 522 ? 244.326 177.904 205.973 1.00 64.56  ? 525 ILE C CB    1 
ATOM   6893 C CG1   . ILE B 2 522 ? 244.555 177.561 204.503 1.00 64.56  ? 525 ILE C CG1   1 
ATOM   6894 C CG2   . ILE B 2 522 ? 243.536 176.810 206.642 1.00 64.56  ? 525 ILE C CG2   1 
ATOM   6895 C CD1   . ILE B 2 522 ? 245.193 176.218 204.287 1.00 64.56  ? 525 ILE C CD1   1 
ATOM   6896 N N     . GLU B 2 523 ? 244.326 180.200 208.228 1.00 69.87  ? 526 GLU C N     1 
ATOM   6897 C CA    . GLU B 2 523 ? 244.199 180.430 209.662 1.00 69.87  ? 526 GLU C CA    1 
ATOM   6898 C C     . GLU B 2 523 ? 243.794 181.850 210.026 1.00 69.87  ? 526 GLU C C     1 
ATOM   6899 O O     . GLU B 2 523 ? 243.146 182.043 211.059 1.00 69.87  ? 526 GLU C O     1 
ATOM   6900 C CB    . GLU B 2 523 ? 245.511 180.103 210.381 1.00 69.87  ? 526 GLU C CB    1 
ATOM   6901 C CG    . GLU B 2 523 ? 246.638 181.081 210.104 1.00 69.87  ? 526 GLU C CG    1 
ATOM   6902 C CD    . GLU B 2 523 ? 247.905 180.741 210.860 1.00 69.87  ? 526 GLU C CD    1 
ATOM   6903 O OE1   . GLU B 2 523 ? 247.922 179.710 211.565 1.00 69.87  ? 526 GLU C OE1   1 
ATOM   6904 O OE2   . GLU B 2 523 ? 248.882 181.512 210.758 1.00 69.87  ? 526 GLU C OE2   1 
ATOM   6905 N N     . LYS B 2 524 ? 244.164 182.844 209.222 1.00 71.64  ? 527 LYS C N     1 
ATOM   6906 C CA    . LYS B 2 524 ? 243.871 184.228 209.566 1.00 71.64  ? 527 LYS C CA    1 
ATOM   6907 C C     . LYS B 2 524 ? 242.361 184.414 209.698 1.00 71.64  ? 527 LYS C C     1 
ATOM   6908 O O     . LYS B 2 524 ? 241.595 183.825 208.928 1.00 71.64  ? 527 LYS C O     1 
ATOM   6909 C CB    . LYS B 2 524 ? 244.443 185.166 208.502 1.00 71.64  ? 527 LYS C CB    1 
ATOM   6910 C CG    . LYS B 2 524 ? 244.849 186.530 209.024 1.00 71.64  ? 527 LYS C CG    1 
ATOM   6911 C CD    . LYS B 2 524 ? 245.815 187.227 208.086 1.00 71.64  ? 527 LYS C CD    1 
ATOM   6912 C CE    . LYS B 2 524 ? 247.253 186.934 208.473 1.00 71.64  ? 527 LYS C CE    1 
ATOM   6913 N NZ    . LYS B 2 524 ? 247.571 187.433 209.838 1.00 71.64  ? 527 LYS C NZ    1 
ATOM   6914 N N     . PRO B 2 525 ? 241.892 185.226 210.654 1.00 70.91  ? 528 PRO C N     1 
ATOM   6915 C CA    . PRO B 2 525 ? 240.466 185.179 211.005 1.00 70.91  ? 528 PRO C CA    1 
ATOM   6916 C C     . PRO B 2 525 ? 239.549 185.834 209.987 1.00 70.91  ? 528 PRO C C     1 
ATOM   6917 O O     . PRO B 2 525 ? 238.626 186.567 210.352 1.00 70.91  ? 528 PRO C O     1 
ATOM   6918 C CB    . PRO B 2 525 ? 240.419 185.924 212.344 1.00 70.91  ? 528 PRO C CB    1 
ATOM   6919 C CG    . PRO B 2 525 ? 241.577 186.844 212.285 1.00 70.91  ? 528 PRO C CG    1 
ATOM   6920 C CD    . PRO B 2 525 ? 242.651 186.066 211.595 1.00 70.91  ? 528 PRO C CD    1 
ATOM   6921 N N     . MET B 2 526 ? 239.807 185.591 208.715 1.00 68.15  ? 529 MET C N     1 
ATOM   6922 C CA    . MET B 2 526 ? 238.771 185.691 207.697 1.00 68.15  ? 529 MET C CA    1 
ATOM   6923 C C     . MET B 2 526 ? 238.939 184.638 206.613 1.00 68.15  ? 529 MET C C     1 
ATOM   6924 O O     . MET B 2 526 ? 238.209 184.681 205.621 1.00 68.15  ? 529 MET C O     1 
ATOM   6925 C CB    . MET B 2 526 ? 238.747 187.096 207.083 1.00 68.15  ? 529 MET C CB    1 
ATOM   6926 C CG    . MET B 2 526 ? 237.384 187.497 206.548 1.00 68.15  ? 529 MET C CG    1 
ATOM   6927 S SD    . MET B 2 526 ? 236.081 187.274 207.770 1.00 68.15  ? 529 MET C SD    1 
ATOM   6928 C CE    . MET B 2 526 ? 234.634 187.190 206.720 1.00 68.15  ? 529 MET C CE    1 
ATOM   6929 N N     . GLY B 2 527 ? 239.871 183.702 206.765 1.00 65.03  ? 530 GLY C N     1 
ATOM   6930 C CA    . GLY B 2 527 ? 240.214 182.765 205.715 1.00 65.03  ? 530 GLY C CA    1 
ATOM   6931 C C     . GLY B 2 527 ? 239.272 181.590 205.604 1.00 65.03  ? 530 GLY C C     1 
ATOM   6932 O O     . GLY B 2 527 ? 238.076 181.685 205.894 1.00 65.03  ? 530 GLY C O     1 
ATOM   6933 N N     . ILE B 2 528 ? 239.826 180.458 205.176 1.00 62.15  ? 531 ILE C N     1 
ATOM   6934 C CA    . ILE B 2 528 ? 239.003 179.300 204.851 1.00 62.15  ? 531 ILE C CA    1 
ATOM   6935 C C     . ILE B 2 528 ? 238.435 178.670 206.115 1.00 62.15  ? 531 ILE C C     1 
ATOM   6936 O O     . ILE B 2 528 ? 237.240 178.368 206.191 1.00 62.15  ? 531 ILE C O     1 
ATOM   6937 C CB    . ILE B 2 528 ? 239.818 178.286 204.032 1.00 62.15  ? 531 ILE C CB    1 
ATOM   6938 C CG1   . ILE B 2 528 ? 240.205 178.896 202.687 1.00 62.15  ? 531 ILE C CG1   1 
ATOM   6939 C CG2   . ILE B 2 528 ? 239.035 177.002 203.841 1.00 62.15  ? 531 ILE C CG2   1 
ATOM   6940 C CD1   . ILE B 2 528 ? 241.054 177.998 201.841 1.00 62.15  ? 531 ILE C CD1   1 
ATOM   6941 N N     . MET B 2 529 ? 239.276 178.470 207.130 1.00 64.61  ? 532 MET C N     1 
ATOM   6942 C CA    . MET B 2 529 ? 238.811 177.784 208.331 1.00 64.61  ? 532 MET C CA    1 
ATOM   6943 C C     . MET B 2 529 ? 237.898 178.674 209.161 1.00 64.61  ? 532 MET C C     1 
ATOM   6944 O O     . MET B 2 529 ? 236.922 178.194 209.748 1.00 64.61  ? 532 MET C O     1 
ATOM   6945 C CB    . MET B 2 529 ? 240.002 177.305 209.158 1.00 64.61  ? 532 MET C CB    1 
ATOM   6946 C CG    . MET B 2 529 ? 240.600 176.004 208.661 1.00 64.61  ? 532 MET C CG    1 
ATOM   6947 S SD    . MET B 2 529 ? 241.886 175.366 209.746 1.00 64.61  ? 532 MET C SD    1 
ATOM   6948 C CE    . MET B 2 529 ? 242.249 173.807 208.945 1.00 64.61  ? 532 MET C CE    1 
ATOM   6949 N N     . SER B 2 530 ? 238.189 179.972 209.218 1.00 64.59  ? 533 SER C N     1 
ATOM   6950 C CA    . SER B 2 530 ? 237.300 180.889 209.922 1.00 64.59  ? 533 SER C CA    1 
ATOM   6951 C C     . SER B 2 530 ? 235.926 180.941 209.266 1.00 64.59  ? 533 SER C C     1 
ATOM   6952 O O     . SER B 2 530 ? 234.899 180.913 209.955 1.00 64.59  ? 533 SER C O     1 
ATOM   6953 C CB    . SER B 2 530 ? 237.923 182.280 209.974 1.00 64.59  ? 533 SER C CB    1 
ATOM   6954 O OG    . SER B 2 530 ? 237.058 183.200 210.608 1.00 64.59  ? 533 SER C OG    1 
ATOM   6955 N N     . ILE B 2 531 ? 235.887 181.011 207.935 1.00 62.61  ? 534 ILE C N     1 
ATOM   6956 C CA    . ILE B 2 531 ? 234.612 181.013 207.227 1.00 62.61  ? 534 ILE C CA    1 
ATOM   6957 C C     . ILE B 2 531 ? 233.893 179.683 207.419 1.00 62.61  ? 534 ILE C C     1 
ATOM   6958 O O     . ILE B 2 531 ? 232.666 179.641 207.554 1.00 62.61  ? 534 ILE C O     1 
ATOM   6959 C CB    . ILE B 2 531 ? 234.834 181.336 205.740 1.00 62.61  ? 534 ILE C CB    1 
ATOM   6960 C CG1   . ILE B 2 531 ? 235.084 182.829 205.561 1.00 62.61  ? 534 ILE C CG1   1 
ATOM   6961 C CG2   . ILE B 2 531 ? 233.645 180.911 204.910 1.00 62.61  ? 534 ILE C CG2   1 
ATOM   6962 C CD1   . ILE B 2 531 ? 235.274 183.242 204.128 1.00 62.61  ? 534 ILE C CD1   1 
ATOM   6963 N N     . LEU B 2 532 ? 234.642 178.580 207.452 1.00 62.21  ? 535 LEU C N     1 
ATOM   6964 C CA    . LEU B 2 532 ? 234.025 177.276 207.668 1.00 62.21  ? 535 LEU C CA    1 
ATOM   6965 C C     . LEU B 2 532 ? 233.385 177.193 209.046 1.00 62.21  ? 535 LEU C C     1 
ATOM   6966 O O     . LEU B 2 532 ? 232.280 176.664 209.196 1.00 62.21  ? 535 LEU C O     1 
ATOM   6967 C CB    . LEU B 2 532 ? 235.065 176.173 207.489 1.00 62.21  ? 535 LEU C CB    1 
ATOM   6968 C CG    . LEU B 2 532 ? 234.673 174.761 207.918 1.00 62.21  ? 535 LEU C CG    1 
ATOM   6969 C CD1   . LEU B 2 532 ? 233.475 174.275 207.140 1.00 62.21  ? 535 LEU C CD1   1 
ATOM   6970 C CD2   . LEU B 2 532 ? 235.842 173.818 207.735 1.00 62.21  ? 535 LEU C CD2   1 
ATOM   6971 N N     . GLU B 2 533 ? 234.058 177.723 210.066 1.00 64.78  ? 536 GLU C N     1 
ATOM   6972 C CA    . GLU B 2 533 ? 233.477 177.714 211.404 1.00 64.78  ? 536 GLU C CA    1 
ATOM   6973 C C     . GLU B 2 533 ? 232.250 178.613 211.478 1.00 64.78  ? 536 GLU C C     1 
ATOM   6974 O O     . GLU B 2 533 ? 231.226 178.233 212.065 1.00 64.78  ? 536 GLU C O     1 
ATOM   6975 C CB    . GLU B 2 533 ? 234.524 178.138 212.429 1.00 64.78  ? 536 GLU C CB    1 
ATOM   6976 C CG    . GLU B 2 533 ? 235.612 177.107 212.638 1.00 64.78  ? 536 GLU C CG    1 
ATOM   6977 C CD    . GLU B 2 533 ? 236.935 177.727 213.021 1.00 64.78  ? 536 GLU C CD    1 
ATOM   6978 O OE1   . GLU B 2 533 ? 236.931 178.828 213.610 1.00 64.78  ? 536 GLU C OE1   1 
ATOM   6979 O OE2   . GLU B 2 533 ? 237.981 177.115 212.727 1.00 64.78  ? 536 GLU C OE2   1 
ATOM   6980 N N     . GLU B 2 534 ? 232.334 179.808 210.889 1.00 63.14  ? 537 GLU C N     1 
ATOM   6981 C CA    . GLU B 2 534 ? 231.172 180.688 210.841 1.00 63.14  ? 537 GLU C CA    1 
ATOM   6982 C C     . GLU B 2 534 ? 229.990 180.008 210.163 1.00 63.14  ? 537 GLU C C     1 
ATOM   6983 O O     . GLU B 2 534 ? 228.848 180.137 210.614 1.00 63.14  ? 537 GLU C O     1 
ATOM   6984 C CB    . GLU B 2 534 ? 231.530 181.986 210.124 1.00 63.14  ? 537 GLU C CB    1 
ATOM   6985 C CG    . GLU B 2 534 ? 230.340 182.724 209.562 1.00 63.14  ? 537 GLU C CG    1 
ATOM   6986 C CD    . GLU B 2 534 ? 230.742 183.911 208.720 1.00 63.14  ? 537 GLU C CD    1 
ATOM   6987 O OE1   . GLU B 2 534 ? 230.048 184.196 207.723 1.00 63.14  ? 537 GLU C OE1   1 
ATOM   6988 O OE2   . GLU B 2 534 ? 231.753 184.562 209.055 1.00 63.14  ? 537 GLU C OE2   1 
ATOM   6989 N N     . GLU B 2 535 ? 230.243 179.269 209.084 1.00 64.64  ? 538 GLU C N     1 
ATOM   6990 C CA    . GLU B 2 535 ? 229.168 178.542 208.418 1.00 64.64  ? 538 GLU C CA    1 
ATOM   6991 C C     . GLU B 2 535 ? 228.659 177.387 209.266 1.00 64.64  ? 538 GLU C C     1 
ATOM   6992 O O     . GLU B 2 535 ? 227.482 177.027 209.177 1.00 64.64  ? 538 GLU C O     1 
ATOM   6993 C CB    . GLU B 2 535 ? 229.639 178.035 207.057 1.00 64.64  ? 538 GLU C CB    1 
ATOM   6994 C CG    . GLU B 2 535 ? 229.815 179.133 206.037 1.00 64.64  ? 538 GLU C CG    1 
ATOM   6995 C CD    . GLU B 2 535 ? 228.520 179.853 205.753 1.00 64.64  ? 538 GLU C CD    1 
ATOM   6996 O OE1   . GLU B 2 535 ? 227.456 179.206 205.810 1.00 64.64  ? 538 GLU C OE1   1 
ATOM   6997 O OE2   . GLU B 2 535 ? 228.559 181.071 205.496 1.00 64.64  ? 538 GLU C OE2   1 
ATOM   6998 N N     . CYS B 2 536 ? 229.522 176.790 210.085 1.00 65.42  ? 539 CYS C N     1 
ATOM   6999 C CA    . CYS B 2 536 ? 229.052 175.765 211.006 1.00 65.42  ? 539 CYS C CA    1 
ATOM   7000 C C     . CYS B 2 536 ? 228.115 176.348 212.054 1.00 65.42  ? 539 CYS C C     1 
ATOM   7001 O O     . CYS B 2 536 ? 227.180 175.672 212.492 1.00 65.42  ? 539 CYS C O     1 
ATOM   7002 C CB    . CYS B 2 536 ? 230.236 175.075 211.678 1.00 65.42  ? 539 CYS C CB    1 
ATOM   7003 S SG    . CYS B 2 536 ? 230.940 173.722 210.718 1.00 65.42  ? 539 CYS C SG    1 
ATOM   7004 N N     . MET B 2 537 ? 228.347 177.595 212.465 1.00 63.38  ? 540 MET C N     1 
ATOM   7005 C CA    . MET B 2 537 ? 227.473 178.222 213.452 1.00 63.38  ? 540 MET C CA    1 
ATOM   7006 C C     . MET B 2 537 ? 226.178 178.752 212.848 1.00 63.38  ? 540 MET C C     1 
ATOM   7007 O O     . MET B 2 537 ? 225.131 178.696 213.500 1.00 63.38  ? 540 MET C O     1 
ATOM   7008 C CB    . MET B 2 537 ? 228.200 179.368 214.150 1.00 63.38  ? 540 MET C CB    1 
ATOM   7009 C CG    . MET B 2 537 ? 228.993 178.962 215.365 1.00 63.38  ? 540 MET C CG    1 
ATOM   7010 S SD    . MET B 2 537 ? 229.665 180.402 216.209 1.00 63.38  ? 540 MET C SD    1 
ATOM   7011 C CE    . MET B 2 537 ? 230.640 181.139 214.904 1.00 63.38  ? 540 MET C CE    1 
ATOM   7012 N N     . PHE B 2 538 ? 226.225 179.270 211.624 1.00 61.62  ? 541 PHE C N     1 
ATOM   7013 C CA    . PHE B 2 538 ? 225.099 180.000 211.065 1.00 61.62  ? 541 PHE C CA    1 
ATOM   7014 C C     . PHE B 2 538 ? 223.907 179.074 210.817 1.00 61.62  ? 541 PHE C C     1 
ATOM   7015 O O     . PHE B 2 538 ? 224.082 177.899 210.487 1.00 61.62  ? 541 PHE C O     1 
ATOM   7016 C CB    . PHE B 2 538 ? 225.510 180.678 209.763 1.00 61.62  ? 541 PHE C CB    1 
ATOM   7017 C CG    . PHE B 2 538 ? 224.712 181.901 209.443 1.00 61.62  ? 541 PHE C CG    1 
ATOM   7018 C CD1   . PHE B 2 538 ? 224.998 183.105 210.055 1.00 61.62  ? 541 PHE C CD1   1 
ATOM   7019 C CD2   . PHE B 2 538 ? 223.676 181.848 208.532 1.00 61.62  ? 541 PHE C CD2   1 
ATOM   7020 C CE1   . PHE B 2 538 ? 224.266 184.232 209.767 1.00 61.62  ? 541 PHE C CE1   1 
ATOM   7021 C CE2   . PHE B 2 538 ? 222.940 182.973 208.241 1.00 61.62  ? 541 PHE C CE2   1 
ATOM   7022 C CZ    . PHE B 2 538 ? 223.236 184.166 208.858 1.00 61.62  ? 541 PHE C CZ    1 
ATOM   7023 N N     . PRO B 2 539 ? 222.683 179.581 210.971 1.00 61.41  ? 542 PRO C N     1 
ATOM   7024 C CA    . PRO B 2 539 ? 221.503 178.735 210.749 1.00 61.41  ? 542 PRO C CA    1 
ATOM   7025 C C     . PRO B 2 539 ? 221.281 178.439 209.275 1.00 61.41  ? 542 PRO C C     1 
ATOM   7026 O O     . PRO B 2 539 ? 221.518 179.284 208.409 1.00 61.41  ? 542 PRO C O     1 
ATOM   7027 C CB    . PRO B 2 539 ? 220.350 179.569 211.320 1.00 61.41  ? 542 PRO C CB    1 
ATOM   7028 C CG    . PRO B 2 539 ? 220.993 180.618 212.163 1.00 61.41  ? 542 PRO C CG    1 
ATOM   7029 C CD    . PRO B 2 539 ? 222.325 180.882 211.558 1.00 61.41  ? 542 PRO C CD    1 
ATOM   7030 N N     . LYS B 2 540 ? 220.817 177.218 209.002 1.00 61.15  ? 543 LYS C N     1 
ATOM   7031 C CA    . LYS B 2 540 ? 220.441 176.761 207.665 1.00 61.15  ? 543 LYS C CA    1 
ATOM   7032 C C     . LYS B 2 540 ? 221.588 176.845 206.665 1.00 61.15  ? 543 LYS C C     1 
ATOM   7033 O O     . LYS B 2 540 ? 221.354 176.997 205.463 1.00 61.15  ? 543 LYS C O     1 
ATOM   7034 C CB    . LYS B 2 540 ? 219.230 177.534 207.133 1.00 61.15  ? 543 LYS C CB    1 
ATOM   7035 C CG    . LYS B 2 540 ? 217.945 177.252 207.874 1.00 61.15  ? 543 LYS C CG    1 
ATOM   7036 C CD    . LYS B 2 540 ? 217.727 175.763 208.040 1.00 61.15  ? 543 LYS C CD    1 
ATOM   7037 C CE    . LYS B 2 540 ? 216.454 175.481 208.808 1.00 61.15  ? 543 LYS C CE    1 
ATOM   7038 N NZ    . LYS B 2 540 ? 216.566 174.221 209.583 1.00 61.15  ? 543 LYS C NZ    1 
ATOM   7039 N N     . ALA B 2 541 ? 222.828 176.752 207.130 1.00 63.73  ? 544 ALA C N     1 
ATOM   7040 C CA    . ALA B 2 541 ? 223.959 176.789 206.219 1.00 63.73  ? 544 ALA C CA    1 
ATOM   7041 C C     . ALA B 2 541 ? 224.089 175.467 205.473 1.00 63.73  ? 544 ALA C C     1 
ATOM   7042 O O     . ALA B 2 541 ? 223.649 174.416 205.942 1.00 63.73  ? 544 ALA C O     1 
ATOM   7043 C CB    . ALA B 2 541 ? 225.246 177.095 206.976 1.00 63.73  ? 544 ALA C CB    1 
ATOM   7044 N N     . SER B 2 542 ? 224.700 175.532 204.294 1.00 68.59  ? 545 SER C N     1 
ATOM   7045 C CA    . SER B 2 542 ? 224.863 174.368 203.437 1.00 68.59  ? 545 SER C CA    1 
ATOM   7046 C C     . SER B 2 542 ? 226.216 174.468 202.746 1.00 68.59  ? 545 SER C C     1 
ATOM   7047 O O     . SER B 2 542 ? 227.030 175.344 203.052 1.00 68.59  ? 545 SER C O     1 
ATOM   7048 C CB    . SER B 2 542 ? 223.708 174.276 202.434 1.00 68.59  ? 545 SER C CB    1 
ATOM   7049 O OG    . SER B 2 542 ? 223.570 175.489 201.717 1.00 68.59  ? 545 SER C OG    1 
ATOM   7050 N N     . ASP B 2 543 ? 226.460 173.560 201.801 1.00 71.83  ? 546 ASP C N     1 
ATOM   7051 C CA    . ASP B 2 543 ? 227.696 173.614 201.030 1.00 71.83  ? 546 ASP C CA    1 
ATOM   7052 C C     . ASP B 2 543 ? 227.688 174.771 200.043 1.00 71.83  ? 546 ASP C C     1 
ATOM   7053 O O     . ASP B 2 543 ? 228.730 175.394 199.810 1.00 71.83  ? 546 ASP C O     1 
ATOM   7054 C CB    . ASP B 2 543 ? 227.912 172.294 200.294 1.00 71.83  ? 546 ASP C CB    1 
ATOM   7055 C CG    . ASP B 2 543 ? 228.154 171.136 201.238 1.00 71.83  ? 546 ASP C CG    1 
ATOM   7056 O OD1   . ASP B 2 543 ? 227.450 170.113 201.118 1.00 71.83  ? 546 ASP C OD1   1 
ATOM   7057 O OD2   . ASP B 2 543 ? 229.050 171.248 202.100 1.00 71.83  ? 546 ASP C OD2   1 
ATOM   7058 N N     . MET B 2 544 ? 226.527 175.079 199.464 1.00 74.17  ? 547 MET C N     1 
ATOM   7059 C CA    . MET B 2 544 ? 226.454 176.157 198.486 1.00 74.17  ? 547 MET C CA    1 
ATOM   7060 C C     . MET B 2 544 ? 226.688 177.511 199.137 1.00 74.17  ? 547 MET C C     1 
ATOM   7061 O O     . MET B 2 544 ? 227.371 178.368 198.567 1.00 74.17  ? 547 MET C O     1 
ATOM   7062 C CB    . MET B 2 544 ? 225.105 176.126 197.774 1.00 74.17  ? 547 MET C CB    1 
ATOM   7063 C CG    . MET B 2 544 ? 224.916 174.931 196.856 1.00 74.17  ? 547 MET C CG    1 
ATOM   7064 S SD    . MET B 2 544 ? 225.721 175.119 195.252 1.00 74.17  ? 547 MET C SD    1 
ATOM   7065 C CE    . MET B 2 544 ? 227.269 174.259 195.527 1.00 74.17  ? 547 MET C CE    1 
ATOM   7066 N N     . THR B 2 545 ? 226.141 177.722 200.335 1.00 69.79  ? 548 THR C N     1 
ATOM   7067 C CA    . THR B 2 545 ? 226.388 178.974 201.041 1.00 69.79  ? 548 THR C CA    1 
ATOM   7068 C C     . THR B 2 545 ? 227.856 179.107 201.423 1.00 69.79  ? 548 THR C C     1 
ATOM   7069 O O     . THR B 2 545 ? 228.422 180.205 201.376 1.00 69.79  ? 548 THR C O     1 
ATOM   7070 C CB    . THR B 2 545 ? 225.505 179.064 202.284 1.00 69.79  ? 548 THR C CB    1 
ATOM   7071 O OG1   . THR B 2 545 ? 225.757 177.937 203.129 1.00 69.79  ? 548 THR C OG1   1 
ATOM   7072 C CG2   . THR B 2 545 ? 224.042 179.072 201.892 1.00 69.79  ? 548 THR C CG2   1 
ATOM   7073 N N     . PHE B 2 546 ? 228.493 177.994 201.789 1.00 65.68  ? 549 PHE C N     1 
ATOM   7074 C CA    . PHE B 2 546 ? 229.912 178.026 202.125 1.00 65.68  ? 549 PHE C CA    1 
ATOM   7075 C C     . PHE B 2 546 ? 230.752 178.380 200.904 1.00 65.68  ? 549 PHE C C     1 
ATOM   7076 O O     . PHE B 2 546 ? 231.668 179.209 200.987 1.00 65.68  ? 549 PHE C O     1 
ATOM   7077 C CB    . PHE B 2 546 ? 230.322 176.675 202.708 1.00 65.68  ? 549 PHE C CB    1 
ATOM   7078 C CG    . PHE B 2 546 ? 231.780 176.561 203.024 1.00 65.68  ? 549 PHE C CG    1 
ATOM   7079 C CD1   . PHE B 2 546 ? 232.453 177.591 203.645 1.00 65.68  ? 549 PHE C CD1   1 
ATOM   7080 C CD2   . PHE B 2 546 ? 232.474 175.409 202.712 1.00 65.68  ? 549 PHE C CD2   1 
ATOM   7081 C CE1   . PHE B 2 546 ? 233.791 177.481 203.936 1.00 65.68  ? 549 PHE C CE1   1 
ATOM   7082 C CE2   . PHE B 2 546 ? 233.810 175.297 203.001 1.00 65.68  ? 549 PHE C CE2   1 
ATOM   7083 C CZ    . PHE B 2 546 ? 234.469 176.334 203.613 1.00 65.68  ? 549 PHE C CZ    1 
ATOM   7084 N N     . LYS B 2 547 ? 230.449 177.762 199.761 1.00 67.04  ? 550 LYS C N     1 
ATOM   7085 C CA    . LYS B 2 547 ? 231.126 178.110 198.516 1.00 67.04  ? 550 LYS C CA    1 
ATOM   7086 C C     . LYS B 2 547 ? 230.928 179.580 198.173 1.00 67.04  ? 550 LYS C C     1 
ATOM   7087 O O     . LYS B 2 547 ? 231.879 180.274 197.783 1.00 67.04  ? 550 LYS C O     1 
ATOM   7088 C CB    . LYS B 2 547 ? 230.608 177.216 197.392 1.00 67.04  ? 550 LYS C CB    1 
ATOM   7089 C CG    . LYS B 2 547 ? 230.888 177.695 195.986 1.00 67.04  ? 550 LYS C CG    1 
ATOM   7090 C CD    . LYS B 2 547 ? 230.124 176.835 194.985 1.00 67.04  ? 550 LYS C CD    1 
ATOM   7091 C CE    . LYS B 2 547 ? 230.381 177.263 193.553 1.00 67.04  ? 550 LYS C CE    1 
ATOM   7092 N NZ    . LYS B 2 547 ? 229.729 176.342 192.585 1.00 67.04  ? 550 LYS C NZ    1 
ATOM   7093 N N     . ALA B 2 548 ? 229.697 180.074 198.318 1.00 67.59  ? 551 ALA C N     1 
ATOM   7094 C CA    . ALA B 2 548 ? 229.418 181.470 198.011 1.00 67.59  ? 551 ALA C CA    1 
ATOM   7095 C C     . ALA B 2 548 ? 230.217 182.404 198.907 1.00 67.59  ? 551 ALA C C     1 
ATOM   7096 O O     . ALA B 2 548 ? 230.773 183.398 198.433 1.00 67.59  ? 551 ALA C O     1 
ATOM   7097 C CB    . ALA B 2 548 ? 227.924 181.746 198.146 1.00 67.59  ? 551 ALA C CB    1 
ATOM   7098 N N     . LYS B 2 549 ? 230.288 182.103 200.205 1.00 67.49  ? 552 LYS C N     1 
ATOM   7099 C CA    . LYS B 2 549 ? 231.036 182.959 201.121 1.00 67.49  ? 552 LYS C CA    1 
ATOM   7100 C C     . LYS B 2 549 ? 232.525 182.942 200.809 1.00 67.49  ? 552 LYS C C     1 
ATOM   7101 O O     . LYS B 2 549 ? 233.183 183.991 200.838 1.00 67.49  ? 552 LYS C O     1 
ATOM   7102 C CB    . LYS B 2 549 ? 230.790 182.529 202.562 1.00 67.49  ? 552 LYS C CB    1 
ATOM   7103 C CG    . LYS B 2 549 ? 229.368 182.737 203.025 1.00 67.49  ? 552 LYS C CG    1 
ATOM   7104 C CD    . LYS B 2 549 ? 229.023 184.211 203.077 1.00 67.49  ? 552 LYS C CD    1 
ATOM   7105 C CE    . LYS B 2 549 ? 229.831 184.908 204.154 1.00 67.49  ? 552 LYS C CE    1 
ATOM   7106 N NZ    . LYS B 2 549 ? 229.502 184.364 205.499 1.00 67.49  ? 552 LYS C NZ    1 
ATOM   7107 N N     . LEU B 2 550 ? 233.077 181.760 200.527 1.00 65.73  ? 553 LEU C N     1 
ATOM   7108 C CA    . LEU B 2 550 ? 234.475 181.678 200.116 1.00 65.73  ? 553 LEU C CA    1 
ATOM   7109 C C     . LEU B 2 550 ? 234.740 182.574 198.916 1.00 65.73  ? 553 LEU C C     1 
ATOM   7110 O O     . LEU B 2 550 ? 235.685 183.373 198.916 1.00 65.73  ? 553 LEU C O     1 
ATOM   7111 C CB    . LEU B 2 550 ? 234.847 180.233 199.792 1.00 65.73  ? 553 LEU C CB    1 
ATOM   7112 C CG    . LEU B 2 550 ? 235.117 179.292 200.960 1.00 65.73  ? 553 LEU C CG    1 
ATOM   7113 C CD1   . LEU B 2 550 ? 235.213 177.872 200.456 1.00 65.73  ? 553 LEU C CD1   1 
ATOM   7114 C CD2   . LEU B 2 550 ? 236.388 179.692 201.678 1.00 65.73  ? 553 LEU C CD2   1 
ATOM   7115 N N     . TYR B 2 551 ? 233.907 182.455 197.881 1.00 69.21  ? 554 TYR C N     1 
ATOM   7116 C CA    . TYR B 2 551 ? 234.120 183.254 196.679 1.00 69.21  ? 554 TYR C CA    1 
ATOM   7117 C C     . TYR B 2 551 ? 233.967 184.743 196.961 1.00 69.21  ? 554 TYR C C     1 
ATOM   7118 O O     . TYR B 2 551 ? 234.739 185.560 196.448 1.00 69.21  ? 554 TYR C O     1 
ATOM   7119 C CB    . TYR B 2 551 ? 233.163 182.808 195.579 1.00 69.21  ? 554 TYR C CB    1 
ATOM   7120 C CG    . TYR B 2 551 ? 233.591 181.528 194.907 1.00 69.21  ? 554 TYR C CG    1 
ATOM   7121 C CD1   . TYR B 2 551 ? 234.933 181.222 194.754 1.00 69.21  ? 554 TYR C CD1   1 
ATOM   7122 C CD2   . TYR B 2 551 ? 232.655 180.629 194.421 1.00 69.21  ? 554 TYR C CD2   1 
ATOM   7123 C CE1   . TYR B 2 551 ? 235.331 180.059 194.141 1.00 69.21  ? 554 TYR C CE1   1 
ATOM   7124 C CE2   . TYR B 2 551 ? 233.046 179.462 193.806 1.00 69.21  ? 554 TYR C CE2   1 
ATOM   7125 C CZ    . TYR B 2 551 ? 234.384 179.182 193.668 1.00 69.21  ? 554 TYR C CZ    1 
ATOM   7126 O OH    . TYR B 2 551 ? 234.776 178.019 193.052 1.00 69.21  ? 554 TYR C OH    1 
ATOM   7127 N N     . ASP B 2 552 ? 232.980 185.117 197.777 1.00 71.32  ? 555 ASP C N     1 
ATOM   7128 C CA    . ASP B 2 552 ? 232.765 186.530 198.070 1.00 71.32  ? 555 ASP C CA    1 
ATOM   7129 C C     . ASP B 2 552 ? 233.943 187.126 198.821 1.00 71.32  ? 555 ASP C C     1 
ATOM   7130 O O     . ASP B 2 552 ? 234.298 188.291 198.607 1.00 71.32  ? 555 ASP C O     1 
ATOM   7131 C CB    . ASP B 2 552 ? 231.479 186.721 198.872 1.00 71.32  ? 555 ASP C CB    1 
ATOM   7132 C CG    . ASP B 2 552 ? 230.251 186.251 198.125 1.00 71.32  ? 555 ASP C CG    1 
ATOM   7133 O OD1   . ASP B 2 552 ? 230.304 186.172 196.880 1.00 71.32  ? 555 ASP C OD1   1 
ATOM   7134 O OD2   . ASP B 2 552 ? 229.231 185.958 198.783 1.00 71.32  ? 555 ASP C OD2   1 
ATOM   7135 N N     . ASN B 2 553 ? 234.562 186.351 199.707 1.00 70.77  ? 556 ASN C N     1 
ATOM   7136 C CA    . ASN B 2 553 ? 235.628 186.905 200.528 1.00 70.77  ? 556 ASN C CA    1 
ATOM   7137 C C     . ASN B 2 553 ? 237.013 186.781 199.909 1.00 70.77  ? 556 ASN C C     1 
ATOM   7138 O O     . ASN B 2 553 ? 237.913 187.526 200.309 1.00 70.77  ? 556 ASN C O     1 
ATOM   7139 C CB    . ASN B 2 553 ? 235.634 186.242 201.906 1.00 70.77  ? 556 ASN C CB    1 
ATOM   7140 C CG    . ASN B 2 553 ? 234.467 186.678 202.761 1.00 70.77  ? 556 ASN C CG    1 
ATOM   7141 O OD1   . ASN B 2 553 ? 234.557 187.660 203.494 1.00 70.77  ? 556 ASN C OD1   1 
ATOM   7142 N ND2   . ASN B 2 553 ? 233.361 185.952 202.671 1.00 70.77  ? 556 ASN C ND2   1 
ATOM   7143 N N     . HIS B 2 554 ? 237.218 185.882 198.947 1.00 68.84  ? 557 HIS C N     1 
ATOM   7144 C CA    . HIS B 2 554 ? 238.592 185.635 198.527 1.00 68.84  ? 557 HIS C CA    1 
ATOM   7145 C C     . HIS B 2 554 ? 238.822 185.703 197.022 1.00 68.84  ? 557 HIS C C     1 
ATOM   7146 O O     . HIS B 2 554 ? 239.939 185.993 196.585 1.00 68.84  ? 557 HIS C O     1 
ATOM   7147 C CB    . HIS B 2 554 ? 239.045 184.280 199.064 1.00 68.84  ? 557 HIS C CB    1 
ATOM   7148 C CG    . HIS B 2 554 ? 239.314 184.285 200.533 1.00 68.84  ? 557 HIS C CG    1 
ATOM   7149 N ND1   . HIS B 2 554 ? 239.933 185.339 201.168 1.00 68.84  ? 557 HIS C ND1   1 
ATOM   7150 C CD2   . HIS B 2 554 ? 239.040 183.375 201.495 1.00 68.84  ? 557 HIS C CD2   1 
ATOM   7151 C CE1   . HIS B 2 554 ? 240.035 185.075 202.457 1.00 68.84  ? 557 HIS C CE1   1 
ATOM   7152 N NE2   . HIS B 2 554 ? 239.500 183.889 202.682 1.00 68.84  ? 557 HIS C NE2   1 
ATOM   7153 N N     . LEU B 2 555 ? 237.800 185.435 196.220 1.00 69.69  ? 558 LEU C N     1 
ATOM   7154 C CA    . LEU B 2 555 ? 237.993 185.385 194.775 1.00 69.69  ? 558 LEU C CA    1 
ATOM   7155 C C     . LEU B 2 555 ? 238.260 186.782 194.229 1.00 69.69  ? 558 LEU C C     1 
ATOM   7156 O O     . LEU B 2 555 ? 237.395 187.660 194.299 1.00 69.69  ? 558 LEU C O     1 
ATOM   7157 C CB    . LEU B 2 555 ? 236.778 184.768 194.093 1.00 69.69  ? 558 LEU C CB    1 
ATOM   7158 C CG    . LEU B 2 555 ? 237.018 184.358 192.642 1.00 69.69  ? 558 LEU C CG    1 
ATOM   7159 C CD1   . LEU B 2 555 ? 238.203 183.423 192.560 1.00 69.69  ? 558 LEU C CD1   1 
ATOM   7160 C CD2   . LEU B 2 555 ? 235.780 183.707 192.055 1.00 69.69  ? 558 LEU C CD2   1 
ATOM   7161 N N     . GLY B 2 556 ? 239.459 186.984 193.683 1.00 73.28  ? 559 GLY C N     1 
ATOM   7162 C CA    . GLY B 2 556 ? 239.863 188.233 193.090 1.00 73.28  ? 559 GLY C CA    1 
ATOM   7163 C C     . GLY B 2 556 ? 240.676 189.125 194.006 1.00 73.28  ? 559 GLY C C     1 
ATOM   7164 O O     . GLY B 2 556 ? 241.487 189.920 193.521 1.00 73.28  ? 559 GLY C O     1 
ATOM   7165 N N     . LYS B 2 557 ? 240.480 189.008 195.317 1.00 75.38  ? 560 LYS C N     1 
ATOM   7166 C CA    . LYS B 2 557 ? 241.189 189.850 196.270 1.00 75.38  ? 560 LYS C CA    1 
ATOM   7167 C C     . LYS B 2 557 ? 242.546 189.284 196.656 1.00 75.38  ? 560 LYS C C     1 
ATOM   7168 O O     . LYS B 2 557 ? 243.491 190.053 196.868 1.00 75.38  ? 560 LYS C O     1 
ATOM   7169 C CB    . LYS B 2 557 ? 240.335 190.049 197.523 1.00 75.38  ? 560 LYS C CB    1 
ATOM   7170 C CG    . LYS B 2 557 ? 238.925 190.517 197.216 1.00 75.38  ? 560 LYS C CG    1 
ATOM   7171 C CD    . LYS B 2 557 ? 238.033 190.462 198.439 1.00 75.38  ? 560 LYS C CD    1 
ATOM   7172 C CE    . LYS B 2 557 ? 236.572 190.543 198.038 1.00 75.38  ? 560 LYS C CE    1 
ATOM   7173 N NZ    . LYS B 2 557 ? 235.668 190.290 199.189 1.00 75.38  ? 560 LYS C NZ    1 
ATOM   7174 N N     . SER B 2 558 ? 242.668 187.964 196.747 1.00 73.87  ? 561 SER C N     1 
ATOM   7175 C CA    . SER B 2 558 ? 243.926 187.304 197.059 1.00 73.87  ? 561 SER C CA    1 
ATOM   7176 C C     . SER B 2 558 ? 244.372 186.488 195.855 1.00 73.87  ? 561 SER C C     1 
ATOM   7177 O O     . SER B 2 558 ? 243.556 185.821 195.212 1.00 73.87  ? 561 SER C O     1 
ATOM   7178 C CB    . SER B 2 558 ? 243.788 186.401 198.286 1.00 73.87  ? 561 SER C CB    1 
ATOM   7179 O OG    . SER B 2 558 ? 243.192 187.100 199.364 1.00 73.87  ? 561 SER C OG    1 
ATOM   7180 N N     . ASN B 2 559 ? 245.667 186.543 195.553 1.00 74.73  ? 562 ASN C N     1 
ATOM   7181 C CA    . ASN B 2 559 ? 246.199 185.889 194.366 1.00 74.73  ? 562 ASN C CA    1 
ATOM   7182 C C     . ASN B 2 559 ? 246.521 184.416 194.581 1.00 74.73  ? 562 ASN C C     1 
ATOM   7183 O O     . ASN B 2 559 ? 246.809 183.714 193.607 1.00 74.73  ? 562 ASN C O     1 
ATOM   7184 C CB    . ASN B 2 559 ? 247.454 186.619 193.879 1.00 74.73  ? 562 ASN C CB    1 
ATOM   7185 C CG    . ASN B 2 559 ? 248.488 186.792 194.972 1.00 74.73  ? 562 ASN C CG    1 
ATOM   7186 O OD1   . ASN B 2 559 ? 248.148 186.962 196.142 1.00 74.73  ? 562 ASN C OD1   1 
ATOM   7187 N ND2   . ASN B 2 559 ? 249.759 186.749 194.594 1.00 74.73  ? 562 ASN C ND2   1 
ATOM   7188 N N     . ASN B 2 560 ? 246.481 183.929 195.821 1.00 72.08  ? 563 ASN C N     1 
ATOM   7189 C CA    . ASN B 2 560 ? 246.692 182.507 196.058 1.00 72.08  ? 563 ASN C CA    1 
ATOM   7190 C C     . ASN B 2 560 ? 245.403 181.711 195.919 1.00 72.08  ? 563 ASN C C     1 
ATOM   7191 O O     . ASN B 2 560 ? 245.440 180.551 195.498 1.00 72.08  ? 563 ASN C O     1 
ATOM   7192 C CB    . ASN B 2 560 ? 247.302 182.287 197.441 1.00 72.08  ? 563 ASN C CB    1 
ATOM   7193 C CG    . ASN B 2 560 ? 248.732 182.779 197.532 1.00 72.08  ? 563 ASN C CG    1 
ATOM   7194 O OD1   . ASN B 2 560 ? 249.668 181.985 197.595 1.00 72.08  ? 563 ASN C OD1   1 
ATOM   7195 N ND2   . ASN B 2 560 ? 248.909 184.094 197.543 1.00 72.08  ? 563 ASN C ND2   1 
ATOM   7196 N N     . PHE B 2 561 ? 244.265 182.308 196.263 1.00 68.80  ? 564 PHE C N     1 
ATOM   7197 C CA    . PHE B 2 561 ? 242.972 181.662 196.086 1.00 68.80  ? 564 PHE C CA    1 
ATOM   7198 C C     . PHE B 2 561 ? 242.533 181.806 194.635 1.00 68.80  ? 564 PHE C C     1 
ATOM   7199 O O     . PHE B 2 561 ? 242.552 182.909 194.082 1.00 68.80  ? 564 PHE C O     1 
ATOM   7200 C CB    . PHE B 2 561 ? 241.941 182.285 197.028 1.00 68.80  ? 564 PHE C CB    1 
ATOM   7201 C CG    . PHE B 2 561 ? 240.609 181.588 197.035 1.00 68.80  ? 564 PHE C CG    1 
ATOM   7202 C CD1   . PHE B 2 561 ? 240.283 180.707 198.047 1.00 68.80  ? 564 PHE C CD1   1 
ATOM   7203 C CD2   . PHE B 2 561 ? 239.670 181.836 196.052 1.00 68.80  ? 564 PHE C CD2   1 
ATOM   7204 C CE1   . PHE B 2 561 ? 239.061 180.075 198.062 1.00 68.80  ? 564 PHE C CE1   1 
ATOM   7205 C CE2   . PHE B 2 561 ? 238.449 181.202 196.065 1.00 68.80  ? 564 PHE C CE2   1 
ATOM   7206 C CZ    . PHE B 2 561 ? 238.144 180.325 197.072 1.00 68.80  ? 564 PHE C CZ    1 
ATOM   7207 N N     . GLN B 2 562 ? 242.138 180.696 194.020 1.00 74.14  ? 565 GLN C N     1 
ATOM   7208 C CA    . GLN B 2 562 ? 241.774 180.688 192.611 1.00 74.14  ? 565 GLN C CA    1 
ATOM   7209 C C     . GLN B 2 562 ? 240.657 179.685 192.372 1.00 74.14  ? 565 GLN C C     1 
ATOM   7210 O O     . GLN B 2 562 ? 240.506 178.704 193.101 1.00 74.14  ? 565 GLN C O     1 
ATOM   7211 C CB    . GLN B 2 562 ? 242.975 180.348 191.720 1.00 74.14  ? 565 GLN C CB    1 
ATOM   7212 C CG    . GLN B 2 562 ? 244.043 181.423 191.677 1.00 74.14  ? 565 GLN C CG    1 
ATOM   7213 C CD    . GLN B 2 562 ? 245.237 181.016 190.850 1.00 74.14  ? 565 GLN C CD    1 
ATOM   7214 O OE1   . GLN B 2 562 ? 245.318 179.887 190.373 1.00 74.14  ? 565 GLN C OE1   1 
ATOM   7215 N NE2   . GLN B 2 562 ? 246.173 181.939 190.669 1.00 74.14  ? 565 GLN C NE2   1 
ATOM   7216 N N     . LYS B 2 563 ? 239.879 179.944 191.336 1.00 80.77  ? 566 LYS C N     1 
ATOM   7217 C CA    . LYS B 2 563 ? 238.832 179.018 190.929 1.00 80.77  ? 566 LYS C CA    1 
ATOM   7218 C C     . LYS B 2 563 ? 239.432 177.931 190.045 1.00 80.77  ? 566 LYS C C     1 
ATOM   7219 O O     . LYS B 2 563 ? 240.190 178.243 189.123 1.00 80.77  ? 566 LYS C O     1 
ATOM   7220 C CB    . LYS B 2 563 ? 237.727 179.765 190.187 1.00 80.77  ? 566 LYS C CB    1 
ATOM   7221 C CG    . LYS B 2 563 ? 236.712 178.879 189.491 1.00 80.77  ? 566 LYS C CG    1 
ATOM   7222 C CD    . LYS B 2 563 ? 235.624 179.705 188.829 1.00 80.77  ? 566 LYS C CD    1 
ATOM   7223 C CE    . LYS B 2 563 ? 236.209 180.792 187.945 1.00 80.77  ? 566 LYS C CE    1 
ATOM   7224 N NZ    . LYS B 2 563 ? 235.183 181.798 187.554 1.00 80.77  ? 566 LYS C NZ    1 
ATOM   7225 N N     . PRO B 2 564 ? 239.122 176.660 190.288 1.00 83.30  ? 567 PRO C N     1 
ATOM   7226 C CA    . PRO B 2 564 ? 239.832 175.586 189.590 1.00 83.30  ? 567 PRO C CA    1 
ATOM   7227 C C     . PRO B 2 564 ? 239.454 175.513 188.121 1.00 83.30  ? 567 PRO C C     1 
ATOM   7228 O O     . PRO B 2 564 ? 238.427 176.032 187.679 1.00 83.30  ? 567 PRO C O     1 
ATOM   7229 C CB    . PRO B 2 564 ? 239.387 174.327 190.337 1.00 83.30  ? 567 PRO C CB    1 
ATOM   7230 C CG    . PRO B 2 564 ? 238.041 174.669 190.844 1.00 83.30  ? 567 PRO C CG    1 
ATOM   7231 C CD    . PRO B 2 564 ? 238.080 176.134 191.183 1.00 83.30  ? 567 PRO C CD    1 
ATOM   7232 N N     . ARG B 2 565 ? 240.319 174.843 187.360 1.00 98.24  ? 568 ARG C N     1 
ATOM   7233 C CA    . ARG B 2 565 ? 240.113 174.636 185.928 1.00 98.24  ? 568 ARG C CA    1 
ATOM   7234 C C     . ARG B 2 565 ? 239.445 173.277 185.749 1.00 98.24  ? 568 ARG C C     1 
ATOM   7235 O O     . ARG B 2 565 ? 240.061 172.287 185.349 1.00 98.24  ? 568 ARG C O     1 
ATOM   7236 C CB    . ARG B 2 565 ? 241.435 174.726 185.176 1.00 98.24  ? 568 ARG C CB    1 
ATOM   7237 C CG    . ARG B 2 565 ? 241.930 176.145 184.933 1.00 98.24  ? 568 ARG C CG    1 
ATOM   7238 C CD    . ARG B 2 565 ? 242.588 176.713 186.181 1.00 98.24  ? 568 ARG C CD    1 
ATOM   7239 N NE    . ARG B 2 565 ? 243.768 175.948 186.575 1.00 98.24  ? 568 ARG C NE    1 
ATOM   7240 C CZ    . ARG B 2 565 ? 244.351 176.033 187.767 1.00 98.24  ? 568 ARG C CZ    1 
ATOM   7241 N NH1   . ARG B 2 565 ? 243.862 176.848 188.692 1.00 98.24  ? 568 ARG C NH1   1 
ATOM   7242 N NH2   . ARG B 2 565 ? 245.421 175.298 188.035 1.00 98.24  ? 568 ARG C NH2   1 
ATOM   7243 N N     . ASN B 2 566 ? 238.153 173.238 186.063 1.00 105.22 ? 569 ASN C N     1 
ATOM   7244 C CA    . ASN B 2 566 ? 237.403 171.990 186.067 1.00 105.22 ? 569 ASN C CA    1 
ATOM   7245 C C     . ASN B 2 566 ? 237.266 171.453 184.648 1.00 105.22 ? 569 ASN C C     1 
ATOM   7246 O O     . ASN B 2 566 ? 236.683 172.107 183.777 1.00 105.22 ? 569 ASN C O     1 
ATOM   7247 C CB    . ASN B 2 566 ? 236.036 172.196 186.717 1.00 105.22 ? 569 ASN C CB    1 
ATOM   7248 C CG    . ASN B 2 566 ? 235.230 173.300 186.058 1.00 105.22 ? 569 ASN C CG    1 
ATOM   7249 O OD1   . ASN B 2 566 ? 235.769 174.122 185.314 1.00 105.22 ? 569 ASN C OD1   1 
ATOM   7250 N ND2   . ASN B 2 566 ? 233.932 173.325 186.330 1.00 105.22 ? 569 ASN C ND2   1 
ATOM   7251 N N     . VAL B 2 567 ? 237.815 170.269 184.417 1.00 111.81 ? 570 VAL C N     1 
ATOM   7252 C CA    . VAL B 2 567 ? 237.760 169.607 183.121 1.00 111.81 ? 570 VAL C CA    1 
ATOM   7253 C C     . VAL B 2 567 ? 236.672 168.546 183.169 1.00 111.81 ? 570 VAL C C     1 
ATOM   7254 O O     . VAL B 2 567 ? 236.512 167.848 184.178 1.00 111.81 ? 570 VAL C O     1 
ATOM   7255 C CB    . VAL B 2 567 ? 239.126 168.995 182.757 1.00 111.81 ? 570 VAL C CB    1 
ATOM   7256 C CG1   . VAL B 2 567 ? 239.032 168.187 181.475 1.00 111.81 ? 570 VAL C CG1   1 
ATOM   7257 C CG2   . VAL B 2 567 ? 240.177 170.089 182.629 1.00 111.81 ? 570 VAL C CG2   1 
ATOM   7258 N N     . LYS B 2 568 ? 235.912 168.430 182.083 1.00 117.21 ? 571 LYS C N     1 
ATOM   7259 C CA    . LYS B 2 568 ? 234.863 167.422 182.002 1.00 117.21 ? 571 LYS C CA    1 
ATOM   7260 C C     . LYS B 2 568 ? 235.493 166.039 181.881 1.00 117.21 ? 571 LYS C C     1 
ATOM   7261 O O     . LYS B 2 568 ? 236.080 165.702 180.848 1.00 117.21 ? 571 LYS C O     1 
ATOM   7262 C CB    . LYS B 2 568 ? 233.941 167.707 180.819 1.00 117.21 ? 571 LYS C CB    1 
ATOM   7263 C CG    . LYS B 2 568 ? 232.863 168.754 181.099 1.00 117.21 ? 571 LYS C CG    1 
ATOM   7264 C CD    . LYS B 2 568 ? 233.437 170.165 181.152 1.00 117.21 ? 571 LYS C CD    1 
ATOM   7265 C CE    . LYS B 2 568 ? 232.347 171.207 181.345 1.00 117.21 ? 571 LYS C CE    1 
ATOM   7266 N NZ    . LYS B 2 568 ? 232.914 172.573 181.522 1.00 117.21 ? 571 LYS C NZ    1 
ATOM   7267 N N     . GLY B 2 569 ? 235.371 165.242 182.937 1.00 114.38 ? 572 GLY C N     1 
ATOM   7268 C CA    . GLY B 2 569 ? 236.027 163.950 183.027 1.00 114.38 ? 572 GLY C CA    1 
ATOM   7269 C C     . GLY B 2 569 ? 236.858 163.755 184.277 1.00 114.38 ? 572 GLY C C     1 
ATOM   7270 O O     . GLY B 2 569 ? 237.387 162.653 184.484 1.00 114.38 ? 572 GLY C O     1 
ATOM   7271 N N     . LYS B 2 570 ? 237.001 164.774 185.118 1.00 108.51 ? 573 LYS C N     1 
ATOM   7272 C CA    . LYS B 2 570 ? 237.716 164.675 186.380 1.00 108.51 ? 573 LYS C CA    1 
ATOM   7273 C C     . LYS B 2 570 ? 236.783 165.064 187.519 1.00 108.51 ? 573 LYS C C     1 
ATOM   7274 O O     . LYS B 2 570 ? 235.679 165.569 187.303 1.00 108.51 ? 573 LYS C O     1 
ATOM   7275 C CB    . LYS B 2 570 ? 238.968 165.565 186.392 1.00 108.51 ? 573 LYS C CB    1 
ATOM   7276 C CG    . LYS B 2 570 ? 240.080 165.118 185.455 1.00 108.51 ? 573 LYS C CG    1 
ATOM   7277 C CD    . LYS B 2 570 ? 239.859 165.614 184.034 1.00 108.51 ? 573 LYS C CD    1 
ATOM   7278 C CE    . LYS B 2 570 ? 240.677 164.817 183.033 1.00 108.51 ? 573 LYS C CE    1 
ATOM   7279 N NZ    . LYS B 2 570 ? 240.275 165.114 181.632 1.00 108.51 ? 573 LYS C NZ    1 
ATOM   7280 N N     . GLN B 2 571 ? 237.237 164.809 188.743 1.00 97.73  ? 574 GLN C N     1 
ATOM   7281 C CA    . GLN B 2 571 ? 236.452 165.161 189.917 1.00 97.73  ? 574 GLN C CA    1 
ATOM   7282 C C     . GLN B 2 571 ? 236.216 166.664 189.963 1.00 97.73  ? 574 GLN C C     1 
ATOM   7283 O O     . GLN B 2 571 ? 237.080 167.458 189.584 1.00 97.73  ? 574 GLN C O     1 
ATOM   7284 C CB    . GLN B 2 571 ? 237.163 164.699 191.188 1.00 97.73  ? 574 GLN C CB    1 
ATOM   7285 C CG    . GLN B 2 571 ? 237.238 163.192 191.344 1.00 97.73  ? 574 GLN C CG    1 
ATOM   7286 C CD    . GLN B 2 571 ? 235.951 162.596 191.873 1.00 97.73  ? 574 GLN C CD    1 
ATOM   7287 O OE1   . GLN B 2 571 ? 235.009 163.315 192.207 1.00 97.73  ? 574 GLN C OE1   1 
ATOM   7288 N NE2   . GLN B 2 571 ? 235.904 161.272 191.952 1.00 97.73  ? 574 GLN C NE2   1 
ATOM   7289 N N     . GLU B 2 572 ? 235.036 167.053 190.431 1.00 90.43  ? 575 GLU C N     1 
ATOM   7290 C CA    . GLU B 2 572 ? 234.646 168.455 190.473 1.00 90.43  ? 575 GLU C CA    1 
ATOM   7291 C C     . GLU B 2 572 ? 235.236 169.109 191.716 1.00 90.43  ? 575 GLU C C     1 
ATOM   7292 O O     . GLU B 2 572 ? 234.940 168.696 192.842 1.00 90.43  ? 575 GLU C O     1 
ATOM   7293 C CB    . GLU B 2 572 ? 233.126 168.593 190.461 1.00 90.43  ? 575 GLU C CB    1 
ATOM   7294 C CG    . GLU B 2 572 ? 232.625 169.853 189.778 1.00 90.43  ? 575 GLU C CG    1 
ATOM   7295 C CD    . GLU B 2 572 ? 232.924 169.874 188.291 1.00 90.43  ? 575 GLU C CD    1 
ATOM   7296 O OE1   . GLU B 2 572 ? 233.268 170.954 187.769 1.00 90.43  ? 575 GLU C OE1   1 
ATOM   7297 O OE2   . GLU B 2 572 ? 232.814 168.812 187.642 1.00 90.43  ? 575 GLU C OE2   1 
ATOM   7298 N N     . ALA B 2 573 ? 236.068 170.122 191.510 1.00 77.89  ? 576 ALA C N     1 
ATOM   7299 C CA    . ALA B 2 573 ? 236.656 170.893 192.590 1.00 77.89  ? 576 ALA C CA    1 
ATOM   7300 C C     . ALA B 2 573 ? 235.992 172.261 192.664 1.00 77.89  ? 576 ALA C C     1 
ATOM   7301 O O     . ALA B 2 573 ? 235.419 172.750 191.688 1.00 77.89  ? 576 ALA C O     1 
ATOM   7302 C CB    . ALA B 2 573 ? 238.165 171.048 192.396 1.00 77.89  ? 576 ALA C CB    1 
ATOM   7303 N N     . HIS B 2 574 ? 236.081 172.880 193.836 1.00 69.52  ? 577 HIS C N     1 
ATOM   7304 C CA    . HIS B 2 574 ? 235.413 174.148 194.079 1.00 69.52  ? 577 HIS C CA    1 
ATOM   7305 C C     . HIS B 2 574 ? 236.356 175.322 194.262 1.00 69.52  ? 577 HIS C C     1 
ATOM   7306 O O     . HIS B 2 574 ? 235.957 176.453 193.989 1.00 69.52  ? 577 HIS C O     1 
ATOM   7307 C CB    . HIS B 2 574 ? 234.503 174.041 195.308 1.00 69.52  ? 577 HIS C CB    1 
ATOM   7308 C CG    . HIS B 2 574 ? 233.443 172.994 195.177 1.00 69.52  ? 577 HIS C CG    1 
ATOM   7309 N ND1   . HIS B 2 574 ? 232.320 173.167 194.400 1.00 69.52  ? 577 HIS C ND1   1 
ATOM   7310 C CD2   . HIS B 2 574 ? 233.342 171.755 195.713 1.00 69.52  ? 577 HIS C CD2   1 
ATOM   7311 C CE1   . HIS B 2 574 ? 231.569 172.083 194.468 1.00 69.52  ? 577 HIS C CE1   1 
ATOM   7312 N NE2   . HIS B 2 574 ? 232.167 171.211 195.258 1.00 69.52  ? 577 HIS C NE2   1 
ATOM   7313 N N     . PHE B 2 575 ? 237.584 175.096 194.714 1.00 65.60  ? 578 PHE C N     1 
ATOM   7314 C CA    . PHE B 2 575 ? 238.574 176.162 194.751 1.00 65.60  ? 578 PHE C CA    1 
ATOM   7315 C C     . PHE B 2 575 ? 239.957 175.533 194.731 1.00 65.60  ? 578 PHE C C     1 
ATOM   7316 O O     . PHE B 2 575 ? 240.113 174.324 194.907 1.00 65.60  ? 578 PHE C O     1 
ATOM   7317 C CB    . PHE B 2 575 ? 238.389 177.071 195.969 1.00 65.60  ? 578 PHE C CB    1 
ATOM   7318 C CG    . PHE B 2 575 ? 238.688 176.413 197.279 1.00 65.60  ? 578 PHE C CG    1 
ATOM   7319 C CD1   . PHE B 2 575 ? 237.760 175.595 197.886 1.00 65.60  ? 578 PHE C CD1   1 
ATOM   7320 C CD2   . PHE B 2 575 ? 239.891 176.632 197.916 1.00 65.60  ? 578 PHE C CD2   1 
ATOM   7321 C CE1   . PHE B 2 575 ? 238.034 175.000 199.091 1.00 65.60  ? 578 PHE C CE1   1 
ATOM   7322 C CE2   . PHE B 2 575 ? 240.165 176.036 199.120 1.00 65.60  ? 578 PHE C CE2   1 
ATOM   7323 C CZ    . PHE B 2 575 ? 239.235 175.220 199.707 1.00 65.60  ? 578 PHE C CZ    1 
ATOM   7324 N N     . SER B 2 576 ? 240.962 176.372 194.506 1.00 68.35  ? 579 SER C N     1 
ATOM   7325 C CA    . SER B 2 576 ? 242.336 175.912 194.386 1.00 68.35  ? 579 SER C CA    1 
ATOM   7326 C C     . SER B 2 576 ? 243.252 176.856 195.140 1.00 68.35  ? 579 SER C C     1 
ATOM   7327 O O     . SER B 2 576 ? 243.150 178.075 194.987 1.00 68.35  ? 579 SER C O     1 
ATOM   7328 C CB    . SER B 2 576 ? 242.765 175.834 192.921 1.00 68.35  ? 579 SER C CB    1 
ATOM   7329 O OG    . SER B 2 576 ? 243.214 177.094 192.462 1.00 68.35  ? 579 SER C OG    1 
ATOM   7330 N N     . LEU B 2 577 ? 244.147 176.294 195.942 1.00 64.15  ? 580 LEU C N     1 
ATOM   7331 C CA    . LEU B 2 577 ? 245.133 177.063 196.683 1.00 64.15  ? 580 LEU C CA    1 
ATOM   7332 C C     . LEU B 2 577 ? 246.502 176.875 196.051 1.00 64.15  ? 580 LEU C C     1 
ATOM   7333 O O     . LEU B 2 577 ? 246.824 175.790 195.562 1.00 64.15  ? 580 LEU C O     1 
ATOM   7334 C CB    . LEU B 2 577 ? 245.174 176.637 198.151 1.00 64.15  ? 580 LEU C CB    1 
ATOM   7335 C CG    . LEU B 2 577 ? 244.019 177.096 199.039 1.00 64.15  ? 580 LEU C CG    1 
ATOM   7336 C CD1   . LEU B 2 577 ? 244.200 176.567 200.440 1.00 64.15  ? 580 LEU C CD1   1 
ATOM   7337 C CD2   . LEU B 2 577 ? 243.936 178.606 199.053 1.00 64.15  ? 580 LEU C CD2   1 
ATOM   7338 N N     . VAL B 2 578 ? 247.307 177.934 196.063 1.00 64.84  ? 581 VAL C N     1 
ATOM   7339 C CA    . VAL B 2 578 ? 248.667 177.881 195.524 1.00 64.84  ? 581 VAL C CA    1 
ATOM   7340 C C     . VAL B 2 578 ? 249.584 177.590 196.707 1.00 64.84  ? 581 VAL C C     1 
ATOM   7341 O O     . VAL B 2 578 ? 250.026 178.487 197.421 1.00 64.84  ? 581 VAL C O     1 
ATOM   7342 C CB    . VAL B 2 578 ? 249.044 179.165 194.793 1.00 64.84  ? 581 VAL C CB    1 
ATOM   7343 C CG1   . VAL B 2 578 ? 250.487 179.106 194.340 1.00 64.84  ? 581 VAL C CG1   1 
ATOM   7344 C CG2   . VAL B 2 578 ? 248.125 179.379 193.607 1.00 64.84  ? 581 VAL C CG2   1 
ATOM   7345 N N     . HIS B 2 579 ? 249.866 176.309 196.916 1.00 64.63  ? 582 HIS C N     1 
ATOM   7346 C CA    . HIS B 2 579 ? 250.675 175.863 198.040 1.00 64.63  ? 582 HIS C CA    1 
ATOM   7347 C C     . HIS B 2 579 ? 252.156 176.002 197.700 1.00 64.63  ? 582 HIS C C     1 
ATOM   7348 O O     . HIS B 2 579 ? 252.536 176.596 196.688 1.00 64.63  ? 582 HIS C O     1 
ATOM   7349 C CB    . HIS B 2 579 ? 250.315 174.429 198.404 1.00 64.63  ? 582 HIS C CB    1 
ATOM   7350 C CG    . HIS B 2 579 ? 249.061 174.307 199.208 1.00 64.63  ? 582 HIS C CG    1 
ATOM   7351 N ND1   . HIS B 2 579 ? 248.946 174.808 200.485 1.00 64.63  ? 582 HIS C ND1   1 
ATOM   7352 C CD2   . HIS B 2 579 ? 247.869 173.736 198.919 1.00 64.63  ? 582 HIS C CD2   1 
ATOM   7353 C CE1   . HIS B 2 579 ? 247.736 174.553 200.948 1.00 64.63  ? 582 HIS C CE1   1 
ATOM   7354 N NE2   . HIS B 2 579 ? 247.062 173.904 200.017 1.00 64.63  ? 582 HIS C NE2   1 
ATOM   7355 N N     . TYR B 2 580 ? 253.018 175.453 198.556 1.00 65.95  ? 583 TYR C N     1 
ATOM   7356 C CA    . TYR B 2 580 ? 254.442 175.404 198.254 1.00 65.95  ? 583 TYR C CA    1 
ATOM   7357 C C     . TYR B 2 580 ? 254.799 174.233 197.350 1.00 65.95  ? 583 TYR C C     1 
ATOM   7358 O O     . TYR B 2 580 ? 255.851 174.264 196.705 1.00 65.95  ? 583 TYR C O     1 
ATOM   7359 C CB    . TYR B 2 580 ? 255.258 175.334 199.551 1.00 65.95  ? 583 TYR C CB    1 
ATOM   7360 C CG    . TYR B 2 580 ? 255.358 173.954 200.162 1.00 65.95  ? 583 TYR C CG    1 
ATOM   7361 C CD1   . TYR B 2 580 ? 254.447 173.532 201.115 1.00 65.95  ? 583 TYR C CD1   1 
ATOM   7362 C CD2   . TYR B 2 580 ? 256.374 173.084 199.804 1.00 65.95  ? 583 TYR C CD2   1 
ATOM   7363 C CE1   . TYR B 2 580 ? 254.534 172.279 201.675 1.00 65.95  ? 583 TYR C CE1   1 
ATOM   7364 C CE2   . TYR B 2 580 ? 256.465 171.829 200.356 1.00 65.95  ? 583 TYR C CE2   1 
ATOM   7365 C CZ    . TYR B 2 580 ? 255.545 171.432 201.293 1.00 65.95  ? 583 TYR C CZ    1 
ATOM   7366 O OH    . TYR B 2 580 ? 255.636 170.182 201.852 1.00 65.95  ? 583 TYR C OH    1 
ATOM   7367 N N     . ALA B 2 581 ? 253.949 173.208 197.290 1.00 66.85  ? 584 ALA C N     1 
ATOM   7368 C CA    . ALA B 2 581 ? 254.192 172.018 196.488 1.00 66.85  ? 584 ALA C CA    1 
ATOM   7369 C C     . ALA B 2 581 ? 253.233 171.919 195.307 1.00 66.85  ? 584 ALA C C     1 
ATOM   7370 O O     . ALA B 2 581 ? 252.814 170.822 194.931 1.00 66.85  ? 584 ALA C O     1 
ATOM   7371 C CB    . ALA B 2 581 ? 254.095 170.764 197.354 1.00 66.85  ? 584 ALA C CB    1 
ATOM   7372 N N     . GLY B 2 582 ? 252.880 173.047 194.718 1.00 65.68  ? 585 GLY C N     1 
ATOM   7373 C CA    . GLY B 2 582 ? 251.965 173.083 193.598 1.00 65.68  ? 585 GLY C CA    1 
ATOM   7374 C C     . GLY B 2 582 ? 250.641 173.715 193.982 1.00 65.68  ? 585 GLY C C     1 
ATOM   7375 O O     . GLY B 2 582 ? 250.513 174.408 194.994 1.00 65.68  ? 585 GLY C O     1 
ATOM   7376 N N     . THR B 2 583 ? 249.642 173.466 193.143 1.00 65.74  ? 586 THR C N     1 
ATOM   7377 C CA    . THR B 2 583 ? 248.284 173.941 193.370 1.00 65.74  ? 586 THR C CA    1 
ATOM   7378 C C     . THR B 2 583 ? 247.379 172.736 193.571 1.00 65.74  ? 586 THR C C     1 
ATOM   7379 O O     . THR B 2 583 ? 247.357 171.826 192.737 1.00 65.74  ? 586 THR C O     1 
ATOM   7380 C CB    . THR B 2 583 ? 247.792 174.791 192.201 1.00 65.74  ? 586 THR C CB    1 
ATOM   7381 O OG1   . THR B 2 583 ? 247.739 173.988 191.019 1.00 65.74  ? 586 THR C OG1   1 
ATOM   7382 C CG2   . THR B 2 583 ? 248.734 175.956 191.966 1.00 65.74  ? 586 THR C CG2   1 
ATOM   7383 N N     . VAL B 2 584 ? 246.642 172.733 194.670 1.00 63.91  ? 587 VAL C N     1 
ATOM   7384 C CA    . VAL B 2 584 ? 245.775 171.622 195.034 1.00 63.91  ? 587 VAL C CA    1 
ATOM   7385 C C     . VAL B 2 584 ? 244.332 172.046 194.812 1.00 63.91  ? 587 VAL C C     1 
ATOM   7386 O O     . VAL B 2 584 ? 243.962 173.193 195.086 1.00 63.91  ? 587 VAL C O     1 
ATOM   7387 C CB    . VAL B 2 584 ? 246.022 171.199 196.493 1.00 63.91  ? 587 VAL C CB    1 
ATOM   7388 C CG1   . VAL B 2 584 ? 245.143 170.033 196.874 1.00 63.91  ? 587 VAL C CG1   1 
ATOM   7389 C CG2   . VAL B 2 584 ? 247.479 170.856 196.693 1.00 63.91  ? 587 VAL C CG2   1 
ATOM   7390 N N     . ASP B 2 585 ? 243.519 171.130 194.298 1.00 67.00  ? 588 ASP C N     1 
ATOM   7391 C CA    . ASP B 2 585 ? 242.113 171.386 194.022 1.00 67.00  ? 588 ASP C CA    1 
ATOM   7392 C C     . ASP B 2 585 ? 241.270 170.706 195.090 1.00 67.00  ? 588 ASP C C     1 
ATOM   7393 O O     . ASP B 2 585 ? 241.283 169.477 195.202 1.00 67.00  ? 588 ASP C O     1 
ATOM   7394 C CB    . ASP B 2 585 ? 241.727 170.872 192.637 1.00 67.00  ? 588 ASP C CB    1 
ATOM   7395 C CG    . ASP B 2 585 ? 242.245 171.751 191.526 1.00 67.00  ? 588 ASP C CG    1 
ATOM   7396 O OD1   . ASP B 2 585 ? 242.332 172.977 191.731 1.00 67.00  ? 588 ASP C OD1   1 
ATOM   7397 O OD2   . ASP B 2 585 ? 242.558 171.218 190.441 1.00 67.00  ? 588 ASP C OD2   1 
ATOM   7398 N N     . TYR B 2 586 ? 240.532 171.499 195.860 1.00 63.25  ? 589 TYR C N     1 
ATOM   7399 C CA    . TYR B 2 586 ? 239.739 170.988 196.965 1.00 63.25  ? 589 TYR C CA    1 
ATOM   7400 C C     . TYR B 2 586 ? 238.269 170.919 196.583 1.00 63.25  ? 589 TYR C C     1 
ATOM   7401 O O     . TYR B 2 586 ? 237.780 171.706 195.770 1.00 63.25  ? 589 TYR C O     1 
ATOM   7402 C CB    . TYR B 2 586 ? 239.904 171.857 198.211 1.00 63.25  ? 589 TYR C CB    1 
ATOM   7403 C CG    . TYR B 2 586 ? 241.324 171.965 198.701 1.00 63.25  ? 589 TYR C CG    1 
ATOM   7404 C CD1   . TYR B 2 586 ? 241.866 171.004 199.536 1.00 63.25  ? 589 TYR C CD1   1 
ATOM   7405 C CD2   . TYR B 2 586 ? 242.119 173.035 198.335 1.00 63.25  ? 589 TYR C CD2   1 
ATOM   7406 C CE1   . TYR B 2 586 ? 243.159 171.103 199.984 1.00 63.25  ? 589 TYR C CE1   1 
ATOM   7407 C CE2   . TYR B 2 586 ? 243.410 173.143 198.780 1.00 63.25  ? 589 TYR C CE2   1 
ATOM   7408 C CZ    . TYR B 2 586 ? 243.926 172.176 199.603 1.00 63.25  ? 589 TYR C CZ    1 
ATOM   7409 O OH    . TYR B 2 586 ? 245.222 172.289 200.045 1.00 63.25  ? 589 TYR C OH    1 
ATOM   7410 N N     . ASN B 2 587 ? 237.569 169.965 197.186 1.00 68.97  ? 590 ASN C N     1 
ATOM   7411 C CA    . ASN B 2 587 ? 236.146 169.747 196.962 1.00 68.97  ? 590 ASN C CA    1 
ATOM   7412 C C     . ASN B 2 587 ? 235.446 169.884 198.306 1.00 68.97  ? 590 ASN C C     1 
ATOM   7413 O O     . ASN B 2 587 ? 235.663 169.070 199.209 1.00 68.97  ? 590 ASN C O     1 
ATOM   7414 C CB    . ASN B 2 587 ? 235.900 168.373 196.343 1.00 68.97  ? 590 ASN C CB    1 
ATOM   7415 C CG    . ASN B 2 587 ? 234.435 168.045 196.222 1.00 68.97  ? 590 ASN C CG    1 
ATOM   7416 O OD1   . ASN B 2 587 ? 233.905 167.238 196.981 1.00 68.97  ? 590 ASN C OD1   1 
ATOM   7417 N ND2   . ASN B 2 587 ? 233.770 168.665 195.259 1.00 68.97  ? 590 ASN C ND2   1 
ATOM   7418 N N     . ILE B 2 588 ? 234.604 170.914 198.441 1.00 67.02  ? 591 ILE C N     1 
ATOM   7419 C CA    . ILE B 2 588 ? 234.036 171.267 199.741 1.00 67.02  ? 591 ILE C CA    1 
ATOM   7420 C C     . ILE B 2 588 ? 232.788 170.482 200.096 1.00 67.02  ? 591 ILE C C     1 
ATOM   7421 O O     . ILE B 2 588 ? 232.195 170.741 201.150 1.00 67.02  ? 591 ILE C O     1 
ATOM   7422 C CB    . ILE B 2 588 ? 233.662 172.759 199.814 1.00 67.02  ? 591 ILE C CB    1 
ATOM   7423 C CG1   . ILE B 2 588 ? 232.538 173.059 198.830 1.00 67.02  ? 591 ILE C CG1   1 
ATOM   7424 C CG2   . ILE B 2 588 ? 234.862 173.627 199.513 1.00 67.02  ? 591 ILE C CG2   1 
ATOM   7425 C CD1   . ILE B 2 588 ? 231.937 174.412 199.010 1.00 67.02  ? 591 ILE C CD1   1 
ATOM   7426 N N     . MET B 2 589 ? 232.358 169.542 199.257 1.00 70.77  ? 592 MET C N     1 
ATOM   7427 C CA    . MET B 2 589 ? 231.113 168.831 199.517 1.00 70.77  ? 592 MET C CA    1 
ATOM   7428 C C     . MET B 2 589 ? 231.193 168.025 200.806 1.00 70.77  ? 592 MET C C     1 
ATOM   7429 O O     . MET B 2 589 ? 231.894 167.011 200.868 1.00 70.77  ? 592 MET C O     1 
ATOM   7430 C CB    . MET B 2 589 ? 230.763 167.910 198.349 1.00 70.77  ? 592 MET C CB    1 
ATOM   7431 C CG    . MET B 2 589 ? 230.182 168.628 197.148 1.00 70.77  ? 592 MET C CG    1 
ATOM   7432 S SD    . MET B 2 589 ? 228.605 169.416 197.501 1.00 70.77  ? 592 MET C SD    1 
ATOM   7433 C CE    . MET B 2 589 ? 228.584 170.696 196.249 1.00 70.77  ? 592 MET C CE    1 
ATOM   7434 N N     . GLY B 2 590 ? 230.472 168.463 201.833 1.00 65.97  ? 593 GLY C N     1 
ATOM   7435 C CA    . GLY B 2 590 ? 230.397 167.745 203.085 1.00 65.97  ? 593 GLY C CA    1 
ATOM   7436 C C     . GLY B 2 590 ? 231.268 168.272 204.201 1.00 65.97  ? 593 GLY C C     1 
ATOM   7437 O O     . GLY B 2 590 ? 231.443 167.572 205.203 1.00 65.97  ? 593 GLY C O     1 
ATOM   7438 N N     . TRP B 2 591 ? 231.822 169.476 204.067 1.00 63.55  ? 594 TRP C N     1 
ATOM   7439 C CA    . TRP B 2 591 ? 232.713 169.984 205.103 1.00 63.55  ? 594 TRP C CA    1 
ATOM   7440 C C     . TRP B 2 591 ? 231.947 170.424 206.342 1.00 63.55  ? 594 TRP C C     1 
ATOM   7441 O O     . TRP B 2 591 ? 232.471 170.325 207.457 1.00 63.55  ? 594 TRP C O     1 
ATOM   7442 C CB    . TRP B 2 591 ? 233.551 171.140 204.564 1.00 63.55  ? 594 TRP C CB    1 
ATOM   7443 C CG    . TRP B 2 591 ? 234.636 170.717 203.633 1.00 63.55  ? 594 TRP C CG    1 
ATOM   7444 C CD1   . TRP B 2 591 ? 234.754 169.515 203.009 1.00 63.55  ? 594 TRP C CD1   1 
ATOM   7445 C CD2   . TRP B 2 591 ? 235.768 171.491 203.230 1.00 63.55  ? 594 TRP C CD2   1 
ATOM   7446 N NE1   . TRP B 2 591 ? 235.883 169.492 202.235 1.00 63.55  ? 594 TRP C NE1   1 
ATOM   7447 C CE2   . TRP B 2 591 ? 236.525 170.695 202.354 1.00 63.55  ? 594 TRP C CE2   1 
ATOM   7448 C CE3   . TRP B 2 591 ? 236.213 172.781 203.520 1.00 63.55  ? 594 TRP C CE3   1 
ATOM   7449 C CZ2   . TRP B 2 591 ? 237.700 171.146 201.767 1.00 63.55  ? 594 TRP C CZ2   1 
ATOM   7450 C CZ3   . TRP B 2 591 ? 237.380 173.225 202.937 1.00 63.55  ? 594 TRP C CZ3   1 
ATOM   7451 C CH2   . TRP B 2 591 ? 238.110 172.411 202.070 1.00 63.55  ? 594 TRP C CH2   1 
ATOM   7452 N N     . LEU B 2 592 ? 230.719 170.917 206.173 1.00 64.95  ? 595 LEU C N     1 
ATOM   7453 C CA    . LEU B 2 592 ? 229.945 171.371 207.324 1.00 64.95  ? 595 LEU C CA    1 
ATOM   7454 C C     . LEU B 2 592 ? 229.581 170.210 208.239 1.00 64.95  ? 595 LEU C C     1 
ATOM   7455 O O     . LEU B 2 592 ? 229.571 170.359 209.465 1.00 64.95  ? 595 LEU C O     1 
ATOM   7456 C CB    . LEU B 2 592 ? 228.688 172.101 206.858 1.00 64.95  ? 595 LEU C CB    1 
ATOM   7457 C CG    . LEU B 2 592 ? 228.894 173.487 206.253 1.00 64.95  ? 595 LEU C CG    1 
ATOM   7458 C CD1   . LEU B 2 592 ? 227.574 174.206 206.120 1.00 64.95  ? 595 LEU C CD1   1 
ATOM   7459 C CD2   . LEU B 2 592 ? 229.838 174.289 207.109 1.00 64.95  ? 595 LEU C CD2   1 
ATOM   7460 N N     . GLU B 2 593 ? 229.281 169.047 207.665 1.00 67.52  ? 596 GLU C N     1 
ATOM   7461 C CA    . GLU B 2 593 ? 228.917 167.897 208.483 1.00 67.52  ? 596 GLU C CA    1 
ATOM   7462 C C     . GLU B 2 593 ? 230.123 167.324 209.211 1.00 67.52  ? 596 GLU C C     1 
ATOM   7463 O O     . GLU B 2 593 ? 229.973 166.741 210.289 1.00 67.52  ? 596 GLU C O     1 
ATOM   7464 C CB    . GLU B 2 593 ? 228.258 166.822 207.620 1.00 67.52  ? 596 GLU C CB    1 
ATOM   7465 C CG    . GLU B 2 593 ? 226.890 167.203 207.056 1.00 67.52  ? 596 GLU C CG    1 
ATOM   7466 C CD    . GLU B 2 593 ? 226.950 168.298 206.001 1.00 67.52  ? 596 GLU C CD    1 
ATOM   7467 O OE1   . GLU B 2 593 ? 228.047 168.555 205.465 1.00 67.52  ? 596 GLU C OE1   1 
ATOM   7468 O OE2   . GLU B 2 593 ? 225.900 168.907 205.711 1.00 67.52  ? 596 GLU C OE2   1 
ATOM   7469 N N     . LYS B 2 594 ? 231.318 167.482 208.646 1.00 64.65  ? 597 LYS C N     1 
ATOM   7470 C CA    . LYS B 2 594 ? 232.532 166.929 209.230 1.00 64.65  ? 597 LYS C CA    1 
ATOM   7471 C C     . LYS B 2 594 ? 233.230 167.884 210.183 1.00 64.65  ? 597 LYS C C     1 
ATOM   7472 O O     . LYS B 2 594 ? 234.031 167.435 211.008 1.00 64.65  ? 597 LYS C O     1 
ATOM   7473 C CB    . LYS B 2 594 ? 233.510 166.528 208.125 1.00 64.65  ? 597 LYS C CB    1 
ATOM   7474 C CG    . LYS B 2 594 ? 233.000 165.423 207.229 1.00 64.65  ? 597 LYS C CG    1 
ATOM   7475 C CD    . LYS B 2 594 ? 234.087 164.919 206.307 1.00 64.65  ? 597 LYS C CD    1 
ATOM   7476 C CE    . LYS B 2 594 ? 234.279 165.856 205.134 1.00 64.65  ? 597 LYS C CE    1 
ATOM   7477 N NZ    . LYS B 2 594 ? 235.167 165.264 204.100 1.00 64.65  ? 597 LYS C NZ    1 
ATOM   7478 N N     . ASN B 2 595 ? 232.957 169.182 210.087 1.00 63.98  ? 598 ASN C N     1 
ATOM   7479 C CA    . ASN B 2 595 ? 233.640 170.154 210.928 1.00 63.98  ? 598 ASN C CA    1 
ATOM   7480 C C     . ASN B 2 595 ? 232.960 170.354 212.277 1.00 63.98  ? 598 ASN C C     1 
ATOM   7481 O O     . ASN B 2 595 ? 233.552 170.968 213.167 1.00 63.98  ? 598 ASN C O     1 
ATOM   7482 C CB    . ASN B 2 595 ? 233.745 171.487 210.186 1.00 63.98  ? 598 ASN C CB    1 
ATOM   7483 C CG    . ASN B 2 595 ? 234.544 172.518 210.946 1.00 63.98  ? 598 ASN C CG    1 
ATOM   7484 O OD1   . ASN B 2 595 ? 235.770 172.513 210.920 1.00 63.98  ? 598 ASN C OD1   1 
ATOM   7485 N ND2   . ASN B 2 595 ? 233.849 173.419 211.621 1.00 63.98  ? 598 ASN C ND2   1 
ATOM   7486 N N     . LYS B 2 596 ? 231.747 169.842 212.458 1.00 64.03  ? 599 LYS C N     1 
ATOM   7487 C CA    . LYS B 2 596 ? 231.034 170.018 213.715 1.00 64.03  ? 599 LYS C CA    1 
ATOM   7488 C C     . LYS B 2 596 ? 231.470 168.978 214.738 1.00 64.03  ? 599 LYS C C     1 
ATOM   7489 O O     . LYS B 2 596 ? 231.655 167.803 214.414 1.00 64.03  ? 599 LYS C O     1 
ATOM   7490 C CB    . LYS B 2 596 ? 229.528 169.930 213.484 1.00 64.03  ? 599 LYS C CB    1 
ATOM   7491 C CG    . LYS B 2 596 ? 229.004 171.013 212.569 1.00 64.03  ? 599 LYS C CG    1 
ATOM   7492 C CD    . LYS B 2 596 ? 227.497 170.996 212.488 1.00 64.03  ? 599 LYS C CD    1 
ATOM   7493 C CE    . LYS B 2 596 ? 227.016 171.877 211.355 1.00 64.03  ? 599 LYS C CE    1 
ATOM   7494 N NZ    . LYS B 2 596 ? 225.537 171.998 211.340 1.00 64.03  ? 599 LYS C NZ    1 
ATOM   7495 N N     . ASP B 2 597 ? 231.626 169.419 215.984 1.00 67.36  ? 600 ASP C N     1 
ATOM   7496 C CA    . ASP B 2 597 ? 232.095 168.557 217.062 1.00 67.36  ? 600 ASP C CA    1 
ATOM   7497 C C     . ASP B 2 597 ? 231.418 168.958 218.369 1.00 67.36  ? 600 ASP C C     1 
ATOM   7498 O O     . ASP B 2 597 ? 232.105 169.289 219.341 1.00 67.36  ? 600 ASP C O     1 
ATOM   7499 C CB    . ASP B 2 597 ? 233.619 168.660 217.182 1.00 67.36  ? 600 ASP C CB    1 
ATOM   7500 C CG    . ASP B 2 597 ? 234.222 167.613 218.107 1.00 67.36  ? 600 ASP C CG    1 
ATOM   7501 O OD1   . ASP B 2 597 ? 235.441 167.367 217.996 1.00 67.36  ? 600 ASP C OD1   1 
ATOM   7502 O OD2   . ASP B 2 597 ? 233.496 167.023 218.934 1.00 67.36  ? 600 ASP C OD2   1 
ATOM   7503 N N     . PRO B 2 598 ? 230.083 168.957 218.441 1.00 66.05  ? 601 PRO C N     1 
ATOM   7504 C CA    . PRO B 2 598 ? 229.424 169.455 219.653 1.00 66.05  ? 601 PRO C CA    1 
ATOM   7505 C C     . PRO B 2 598 ? 229.367 168.411 220.755 1.00 66.05  ? 601 PRO C C     1 
ATOM   7506 O O     . PRO B 2 598 ? 228.764 167.348 220.587 1.00 66.05  ? 601 PRO C O     1 
ATOM   7507 C CB    . PRO B 2 598 ? 228.028 169.831 219.151 1.00 66.05  ? 601 PRO C CB    1 
ATOM   7508 C CG    . PRO B 2 598 ? 227.772 168.865 218.047 1.00 66.05  ? 601 PRO C CG    1 
ATOM   7509 C CD    . PRO B 2 598 ? 229.103 168.469 217.454 1.00 66.05  ? 601 PRO C CD    1 
ATOM   7510 N N     . LEU B 2 599 ? 229.992 168.705 221.889 1.00 66.35  ? 602 LEU C N     1 
ATOM   7511 C CA    . LEU B 2 599 ? 230.074 167.757 222.989 1.00 66.35  ? 602 LEU C CA    1 
ATOM   7512 C C     . LEU B 2 599 ? 228.887 167.918 223.928 1.00 66.35  ? 602 LEU C C     1 
ATOM   7513 O O     . LEU B 2 599 ? 228.475 169.037 224.245 1.00 66.35  ? 602 LEU C O     1 
ATOM   7514 C CB    . LEU B 2 599 ? 231.379 167.943 223.761 1.00 66.35  ? 602 LEU C CB    1 
ATOM   7515 C CG    . LEU B 2 599 ? 231.871 166.719 224.530 1.00 66.35  ? 602 LEU C CG    1 
ATOM   7516 C CD1   . LEU B 2 599 ? 231.688 165.463 223.703 1.00 66.35  ? 602 LEU C CD1   1 
ATOM   7517 C CD2   . LEU B 2 599 ? 233.325 166.891 224.925 1.00 66.35  ? 602 LEU C CD2   1 
ATOM   7518 N N     . ASN B 2 600 ? 228.344 166.788 224.372 1.00 65.20  ? 603 ASN C N     1 
ATOM   7519 C CA    . ASN B 2 600 ? 227.207 166.750 225.284 1.00 65.20  ? 603 ASN C CA    1 
ATOM   7520 C C     . ASN B 2 600 ? 227.748 166.565 226.695 1.00 65.20  ? 603 ASN C C     1 
ATOM   7521 O O     . ASN B 2 600 ? 228.215 165.479 227.049 1.00 65.20  ? 603 ASN C O     1 
ATOM   7522 C CB    . ASN B 2 600 ? 226.254 165.620 224.901 1.00 65.20  ? 603 ASN C CB    1 
ATOM   7523 C CG    . ASN B 2 600 ? 224.934 165.685 225.641 1.00 65.20  ? 603 ASN C CG    1 
ATOM   7524 O OD1   . ASN B 2 600 ? 224.861 166.161 226.770 1.00 65.20  ? 603 ASN C OD1   1 
ATOM   7525 N ND2   . ASN B 2 600 ? 223.881 165.194 225.006 1.00 65.20  ? 603 ASN C ND2   1 
ATOM   7526 N N     . GLU B 2 601 ? 227.684 167.624 227.503 1.00 67.13  ? 604 GLU C N     1 
ATOM   7527 C CA    . GLU B 2 601 ? 228.275 167.564 228.833 1.00 67.13  ? 604 GLU C CA    1 
ATOM   7528 C C     . GLU B 2 601 ? 227.461 166.721 229.803 1.00 67.13  ? 604 GLU C C     1 
ATOM   7529 O O     . GLU B 2 601 ? 228.011 166.253 230.803 1.00 67.13  ? 604 GLU C O     1 
ATOM   7530 C CB    . GLU B 2 601 ? 228.460 168.973 229.388 1.00 67.13  ? 604 GLU C CB    1 
ATOM   7531 C CG    . GLU B 2 601 ? 229.645 169.699 228.782 1.00 67.13  ? 604 GLU C CG    1 
ATOM   7532 C CD    . GLU B 2 601 ? 229.862 171.065 229.390 1.00 67.13  ? 604 GLU C CD    1 
ATOM   7533 O OE1   . GLU B 2 601 ? 228.887 171.643 229.912 1.00 67.13  ? 604 GLU C OE1   1 
ATOM   7534 O OE2   . GLU B 2 601 ? 231.007 171.558 229.347 1.00 67.13  ? 604 GLU C OE2   1 
ATOM   7535 N N     . THR B 2 602 ? 226.175 166.505 229.533 1.00 64.96  ? 605 THR C N     1 
ATOM   7536 C CA    . THR B 2 602 ? 225.399 165.593 230.365 1.00 64.96  ? 605 THR C CA    1 
ATOM   7537 C C     . THR B 2 602 ? 225.901 164.159 230.227 1.00 64.96  ? 605 THR C C     1 
ATOM   7538 O O     . THR B 2 602 ? 226.064 163.447 231.226 1.00 64.96  ? 605 THR C O     1 
ATOM   7539 C CB    . THR B 2 602 ? 223.921 165.685 229.998 1.00 64.96  ? 605 THR C CB    1 
ATOM   7540 O OG1   . THR B 2 602 ? 223.507 167.054 230.043 1.00 64.96  ? 605 THR C OG1   1 
ATOM   7541 C CG2   . THR B 2 602 ? 223.079 164.876 230.966 1.00 64.96  ? 605 THR C CG2   1 
ATOM   7542 N N     . VAL B 2 603 ? 226.169 163.719 228.997 1.00 63.01  ? 606 VAL C N     1 
ATOM   7543 C CA    . VAL B 2 603 ? 226.693 162.372 228.820 1.00 63.01  ? 606 VAL C CA    1 
ATOM   7544 C C     . VAL B 2 603 ? 228.126 162.284 229.327 1.00 63.01  ? 606 VAL C C     1 
ATOM   7545 O O     . VAL B 2 603 ? 228.558 161.230 229.799 1.00 63.01  ? 606 VAL C O     1 
ATOM   7546 C CB    . VAL B 2 603 ? 226.580 161.937 227.350 1.00 63.01  ? 606 VAL C CB    1 
ATOM   7547 C CG1   . VAL B 2 603 ? 227.002 160.494 227.199 1.00 63.01  ? 606 VAL C CG1   1 
ATOM   7548 C CG2   . VAL B 2 603 ? 225.161 162.122 226.863 1.00 63.01  ? 606 VAL C CG2   1 
ATOM   7549 N N     . VAL B 2 604 ? 228.881 163.382 229.271 1.00 63.86  ? 607 VAL C N     1 
ATOM   7550 C CA    . VAL B 2 604 ? 230.213 163.374 229.868 1.00 63.86  ? 607 VAL C CA    1 
ATOM   7551 C C     . VAL B 2 604 ? 230.115 163.233 231.382 1.00 63.86  ? 607 VAL C C     1 
ATOM   7552 O O     . VAL B 2 604 ? 230.934 162.550 232.011 1.00 63.86  ? 607 VAL C O     1 
ATOM   7553 C CB    . VAL B 2 604 ? 230.992 164.635 229.454 1.00 63.86  ? 607 VAL C CB    1 
ATOM   7554 C CG1   . VAL B 2 604 ? 232.299 164.727 230.208 1.00 63.86  ? 607 VAL C CG1   1 
ATOM   7555 C CG2   . VAL B 2 604 ? 231.261 164.612 227.965 1.00 63.86  ? 607 VAL C CG2   1 
ATOM   7556 N N     . GLY B 2 605 ? 229.108 163.859 231.993 1.00 65.10  ? 608 GLY C N     1 
ATOM   7557 C CA    . GLY B 2 605 ? 228.889 163.670 233.414 1.00 65.10  ? 608 GLY C CA    1 
ATOM   7558 C C     . GLY B 2 605 ? 228.470 162.256 233.754 1.00 65.10  ? 608 GLY C C     1 
ATOM   7559 O O     . GLY B 2 605 ? 228.825 161.737 234.815 1.00 65.10  ? 608 GLY C O     1 
ATOM   7560 N N     . LEU B 2 606 ? 227.704 161.619 232.870 1.00 64.18  ? 609 LEU C N     1 
ATOM   7561 C CA    . LEU B 2 606 ? 227.414 160.199 233.044 1.00 64.18  ? 609 LEU C CA    1 
ATOM   7562 C C     . LEU B 2 606 ? 228.679 159.361 232.919 1.00 64.18  ? 609 LEU C C     1 
ATOM   7563 O O     . LEU B 2 606 ? 228.837 158.355 233.618 1.00 64.18  ? 609 LEU C O     1 
ATOM   7564 C CB    . LEU B 2 606 ? 226.376 159.739 232.024 1.00 64.18  ? 609 LEU C CB    1 
ATOM   7565 C CG    . LEU B 2 606 ? 224.928 160.154 232.265 1.00 64.18  ? 609 LEU C CG    1 
ATOM   7566 C CD1   . LEU B 2 606 ? 224.025 159.501 231.239 1.00 64.18  ? 609 LEU C CD1   1 
ATOM   7567 C CD2   . LEU B 2 606 ? 224.503 159.780 233.668 1.00 64.18  ? 609 LEU C CD2   1 
ATOM   7568 N N     . TYR B 2 607 ? 229.587 159.761 232.027 1.00 65.82  ? 610 TYR C N     1 
ATOM   7569 C CA    . TYR B 2 607 ? 230.834 159.027 231.834 1.00 65.82  ? 610 TYR C CA    1 
ATOM   7570 C C     . TYR B 2 607 ? 231.705 159.097 233.078 1.00 65.82  ? 610 TYR C C     1 
ATOM   7571 O O     . TYR B 2 607 ? 232.270 158.088 233.513 1.00 65.82  ? 610 TYR C O     1 
ATOM   7572 C CB    . TYR B 2 607 ? 231.598 159.591 230.638 1.00 65.82  ? 610 TYR C CB    1 
ATOM   7573 C CG    . TYR B 2 607 ? 231.073 159.195 229.282 1.00 65.82  ? 610 TYR C CG    1 
ATOM   7574 C CD1   . TYR B 2 607 ? 230.215 158.121 229.129 1.00 65.82  ? 610 TYR C CD1   1 
ATOM   7575 C CD2   . TYR B 2 607 ? 231.450 159.898 228.149 1.00 65.82  ? 610 TYR C CD2   1 
ATOM   7576 C CE1   . TYR B 2 607 ? 229.742 157.765 227.887 1.00 65.82  ? 610 TYR C CE1   1 
ATOM   7577 C CE2   . TYR B 2 607 ? 230.984 159.550 226.908 1.00 65.82  ? 610 TYR C CE2   1 
ATOM   7578 C CZ    . TYR B 2 607 ? 230.131 158.484 226.780 1.00 65.82  ? 610 TYR C CZ    1 
ATOM   7579 O OH    . TYR B 2 607 ? 229.668 158.137 225.535 1.00 65.82  ? 610 TYR C OH    1 
ATOM   7580 N N     . GLN B 2 608 ? 231.840 160.293 233.653 1.00 67.20  ? 611 GLN C N     1 
ATOM   7581 C CA    . GLN B 2 608 ? 232.704 160.485 234.813 1.00 67.20  ? 611 GLN C CA    1 
ATOM   7582 C C     . GLN B 2 608 ? 232.309 159.618 235.999 1.00 67.20  ? 611 GLN C C     1 
ATOM   7583 O O     . GLN B 2 608 ? 233.119 159.454 236.917 1.00 67.20  ? 611 GLN C O     1 
ATOM   7584 C CB    . GLN B 2 608 ? 232.705 161.949 235.248 1.00 67.20  ? 611 GLN C CB    1 
ATOM   7585 C CG    . GLN B 2 608 ? 233.125 162.922 234.175 1.00 67.20  ? 611 GLN C CG    1 
ATOM   7586 C CD    . GLN B 2 608 ? 233.464 164.288 234.732 1.00 67.20  ? 611 GLN C CD    1 
ATOM   7587 O OE1   . GLN B 2 608 ? 233.658 164.447 235.936 1.00 67.20  ? 611 GLN C OE1   1 
ATOM   7588 N NE2   . GLN B 2 608 ? 233.537 165.284 233.857 1.00 67.20  ? 611 GLN C NE2   1 
ATOM   7589 N N     . LYS B 2 609 ? 231.097 159.064 236.007 1.00 69.56  ? 612 LYS C N     1 
ATOM   7590 C CA    . LYS B 2 609 ? 230.619 158.224 237.098 1.00 69.56  ? 612 LYS C CA    1 
ATOM   7591 C C     . LYS B 2 609 ? 230.303 156.809 236.631 1.00 69.56  ? 612 LYS C C     1 
ATOM   7592 O O     . LYS B 2 609 ? 229.440 156.145 237.211 1.00 69.56  ? 612 LYS C O     1 
ATOM   7593 C CB    . LYS B 2 609 ? 229.390 158.853 237.753 1.00 69.56  ? 612 LYS C CB    1 
ATOM   7594 C CG    . LYS B 2 609 ? 229.581 160.308 238.130 1.00 69.56  ? 612 LYS C CG    1 
ATOM   7595 C CD    . LYS B 2 609 ? 228.437 160.818 238.982 1.00 69.56  ? 612 LYS C CD    1 
ATOM   7596 C CE    . LYS B 2 609 ? 228.695 162.244 239.428 1.00 69.56  ? 612 LYS C CE    1 
ATOM   7597 N NZ    . LYS B 2 609 ? 227.779 162.669 240.519 1.00 69.56  ? 612 LYS C NZ    1 
ATOM   7598 N N     . SER B 2 610 ? 230.979 156.339 235.589 1.00 70.49  ? 613 SER C N     1 
ATOM   7599 C CA    . SER B 2 610 ? 230.712 155.018 235.050 1.00 70.49  ? 613 SER C CA    1 
ATOM   7600 C C     . SER B 2 610 ? 231.219 153.932 235.994 1.00 70.49  ? 613 SER C C     1 
ATOM   7601 O O     . SER B 2 610 ? 232.130 154.141 236.798 1.00 70.49  ? 613 SER C O     1 
ATOM   7602 C CB    . SER B 2 610 ? 231.363 154.863 233.678 1.00 70.49  ? 613 SER C CB    1 
ATOM   7603 O OG    . SER B 2 610 ? 231.481 153.497 233.326 1.00 70.49  ? 613 SER C OG    1 
ATOM   7604 N N     . SER B 2 611 ? 230.609 152.752 235.881 1.00 72.58  ? 614 SER C N     1 
ATOM   7605 C CA    . SER B 2 611 ? 231.044 151.607 236.670 1.00 72.58  ? 614 SER C CA    1 
ATOM   7606 C C     . SER B 2 611 ? 232.359 151.032 236.163 1.00 72.58  ? 614 SER C C     1 
ATOM   7607 O O     . SER B 2 611 ? 233.162 150.536 236.960 1.00 72.58  ? 614 SER C O     1 
ATOM   7608 C CB    . SER B 2 611 ? 229.967 150.525 236.663 1.00 72.58  ? 614 SER C CB    1 
ATOM   7609 O OG    . SER B 2 611 ? 230.395 149.382 237.378 1.00 72.58  ? 614 SER C OG    1 
ATOM   7610 N N     . LEU B 2 612 ? 232.592 151.086 234.856 1.00 72.68  ? 615 LEU C N     1 
ATOM   7611 C CA    . LEU B 2 612 ? 233.843 150.612 234.280 1.00 72.68  ? 615 LEU C CA    1 
ATOM   7612 C C     . LEU B 2 612 ? 234.973 151.570 234.643 1.00 72.68  ? 615 LEU C C     1 
ATOM   7613 O O     . LEU B 2 612 ? 234.912 152.761 234.326 1.00 72.68  ? 615 LEU C O     1 
ATOM   7614 C CB    . LEU B 2 612 ? 233.688 150.477 232.768 1.00 72.68  ? 615 LEU C CB    1 
ATOM   7615 C CG    . LEU B 2 612 ? 234.795 149.863 231.919 1.00 72.68  ? 615 LEU C CG    1 
ATOM   7616 C CD1   . LEU B 2 612 ? 234.185 149.119 230.758 1.00 72.68  ? 615 LEU C CD1   1 
ATOM   7617 C CD2   . LEU B 2 612 ? 235.680 150.957 231.394 1.00 72.68  ? 615 LEU C CD2   1 
ATOM   7618 N N     . LYS B 2 613 ? 236.004 151.047 235.312 1.00 72.16  ? 616 LYS C N     1 
ATOM   7619 C CA    . LYS B 2 613 ? 237.038 151.903 235.884 1.00 72.16  ? 616 LYS C CA    1 
ATOM   7620 C C     . LYS B 2 613 ? 237.800 152.684 234.822 1.00 72.16  ? 616 LYS C C     1 
ATOM   7621 O O     . LYS B 2 613 ? 238.229 153.815 235.076 1.00 72.16  ? 616 LYS C O     1 
ATOM   7622 C CB    . LYS B 2 613 ? 238.008 151.064 236.715 1.00 72.16  ? 616 LYS C CB    1 
ATOM   7623 C CG    . LYS B 2 613 ? 237.368 150.387 237.914 1.00 72.16  ? 616 LYS C CG    1 
ATOM   7624 C CD    . LYS B 2 613 ? 238.186 149.196 238.384 1.00 72.16  ? 616 LYS C CD    1 
ATOM   7625 C CE    . LYS B 2 613 ? 239.660 149.546 238.503 1.00 72.16  ? 616 LYS C CE    1 
ATOM   7626 N NZ    . LYS B 2 613 ? 240.536 148.384 238.188 1.00 72.16  ? 616 LYS C NZ    1 
ATOM   7627 N N     . LEU B 2 614 ? 237.986 152.106 233.635 1.00 69.96  ? 617 LEU C N     1 
ATOM   7628 C CA    . LEU B 2 614 ? 238.768 152.785 232.607 1.00 69.96  ? 617 LEU C CA    1 
ATOM   7629 C C     . LEU B 2 614 ? 238.049 154.027 232.091 1.00 69.96  ? 617 LEU C C     1 
ATOM   7630 O O     . LEU B 2 614 ? 238.692 155.033 231.778 1.00 69.96  ? 617 LEU C O     1 
ATOM   7631 C CB    . LEU B 2 614 ? 239.082 151.821 231.465 1.00 69.96  ? 617 LEU C CB    1 
ATOM   7632 C CG    . LEU B 2 614 ? 239.750 152.399 230.220 1.00 69.96  ? 617 LEU C CG    1 
ATOM   7633 C CD1   . LEU B 2 614 ? 241.020 153.134 230.590 1.00 69.96  ? 617 LEU C CD1   1 
ATOM   7634 C CD2   . LEU B 2 614 ? 240.049 151.292 229.238 1.00 69.96  ? 617 LEU C CD2   1 
ATOM   7635 N N     . MET B 2 615 ? 236.719 153.984 232.003 1.00 70.47  ? 618 MET C N     1 
ATOM   7636 C CA    . MET B 2 615 ? 235.974 155.164 231.573 1.00 70.47  ? 618 MET C CA    1 
ATOM   7637 C C     . MET B 2 615 ? 236.102 156.296 232.585 1.00 70.47  ? 618 MET C C     1 
ATOM   7638 O O     . MET B 2 615 ? 236.276 157.463 232.208 1.00 70.47  ? 618 MET C O     1 
ATOM   7639 C CB    . MET B 2 615 ? 234.506 154.800 231.358 1.00 70.47  ? 618 MET C CB    1 
ATOM   7640 C CG    . MET B 2 615 ? 233.651 155.951 230.880 1.00 70.47  ? 618 MET C CG    1 
ATOM   7641 S SD    . MET B 2 615 ? 234.074 156.524 229.229 1.00 70.47  ? 618 MET C SD    1 
ATOM   7642 C CE    . MET B 2 615 ? 233.296 155.261 228.238 1.00 70.47  ? 618 MET C CE    1 
ATOM   7643 N N     . ALA B 2 616 ? 236.018 155.969 233.875 1.00 70.19  ? 619 ALA C N     1 
ATOM   7644 C CA    . ALA B 2 616 ? 236.208 156.981 234.906 1.00 70.19  ? 619 ALA C CA    1 
ATOM   7645 C C     . ALA B 2 616 ? 237.629 157.523 234.880 1.00 70.19  ? 619 ALA C C     1 
ATOM   7646 O O     . ALA B 2 616 ? 237.852 158.713 235.127 1.00 70.19  ? 619 ALA C O     1 
ATOM   7647 C CB    . ALA B 2 616 ? 235.875 156.399 236.278 1.00 70.19  ? 619 ALA C CB    1 
ATOM   7648 N N     . THR B 2 617 ? 238.604 156.665 234.576 1.00 71.11  ? 620 THR C N     1 
ATOM   7649 C CA    . THR B 2 617 ? 239.974 157.138 234.407 1.00 71.11  ? 620 THR C CA    1 
ATOM   7650 C C     . THR B 2 617 ? 240.076 158.120 233.247 1.00 71.11  ? 620 THR C C     1 
ATOM   7651 O O     . THR B 2 617 ? 240.715 159.171 233.366 1.00 71.11  ? 620 THR C O     1 
ATOM   7652 C CB    . THR B 2 617 ? 240.915 155.955 234.185 1.00 71.11  ? 620 THR C CB    1 
ATOM   7653 O OG1   . THR B 2 617 ? 240.770 155.020 235.260 1.00 71.11  ? 620 THR C OG1   1 
ATOM   7654 C CG2   . THR B 2 617 ? 242.353 156.426 234.129 1.00 71.11  ? 620 THR C CG2   1 
ATOM   7655 N N     . LEU B 2 618 ? 239.448 157.791 232.118 1.00 69.82  ? 621 LEU C N     1 
ATOM   7656 C CA    . LEU B 2 618 ? 239.533 158.648 230.940 1.00 69.82  ? 621 LEU C CA    1 
ATOM   7657 C C     . LEU B 2 618 ? 238.882 160.000 231.185 1.00 69.82  ? 621 LEU C C     1 
ATOM   7658 O O     . LEU B 2 618 ? 239.406 161.034 230.759 1.00 69.82  ? 621 LEU C O     1 
ATOM   7659 C CB    . LEU B 2 618 ? 238.882 157.964 229.740 1.00 69.82  ? 621 LEU C CB    1 
ATOM   7660 C CG    . LEU B 2 618 ? 239.557 156.713 229.192 1.00 69.82  ? 621 LEU C CG    1 
ATOM   7661 C CD1   . LEU B 2 618 ? 238.767 156.170 228.024 1.00 69.82  ? 621 LEU C CD1   1 
ATOM   7662 C CD2   . LEU B 2 618 ? 240.966 157.040 228.776 1.00 69.82  ? 621 LEU C CD2   1 
ATOM   7663 N N     . PHE B 2 619 ? 237.737 160.018 231.864 1.00 68.91  ? 622 PHE C N     1 
ATOM   7664 C CA    . PHE B 2 619 ? 236.995 161.256 232.071 1.00 68.91  ? 622 PHE C CA    1 
ATOM   7665 C C     . PHE B 2 619 ? 237.105 161.780 233.500 1.00 68.91  ? 622 PHE C C     1 
ATOM   7666 O O     . PHE B 2 619 ? 236.220 162.495 233.970 1.00 68.91  ? 622 PHE C O     1 
ATOM   7667 C CB    . PHE B 2 619 ? 235.534 161.073 231.673 1.00 68.91  ? 622 PHE C CB    1 
ATOM   7668 C CG    . PHE B 2 619 ? 235.330 160.970 230.196 1.00 68.91  ? 622 PHE C CG    1 
ATOM   7669 C CD1   . PHE B 2 619 ? 235.178 162.107 229.429 1.00 68.91  ? 622 PHE C CD1   1 
ATOM   7670 C CD2   . PHE B 2 619 ? 235.316 159.741 229.569 1.00 68.91  ? 622 PHE C CD2   1 
ATOM   7671 C CE1   . PHE B 2 619 ? 234.999 162.019 228.069 1.00 68.91  ? 622 PHE C CE1   1 
ATOM   7672 C CE2   . PHE B 2 619 ? 235.138 159.648 228.207 1.00 68.91  ? 622 PHE C CE2   1 
ATOM   7673 C CZ    . PHE B 2 619 ? 234.979 160.789 227.457 1.00 68.91  ? 622 PHE C CZ    1 
ATOM   7674 N N     . SER B 2 620 ? 238.187 161.432 234.200 1.00 74.76  ? 623 SER C N     1 
ATOM   7675 C CA    . SER B 2 620 ? 238.429 161.996 235.525 1.00 74.76  ? 623 SER C CA    1 
ATOM   7676 C C     . SER B 2 620 ? 238.450 163.519 235.487 1.00 74.76  ? 623 SER C C     1 
ATOM   7677 O O     . SER B 2 620 ? 238.065 164.177 236.461 1.00 74.76  ? 623 SER C O     1 
ATOM   7678 C CB    . SER B 2 620 ? 239.743 161.458 236.089 1.00 74.76  ? 623 SER C CB    1 
ATOM   7679 O OG    . SER B 2 620 ? 240.843 161.896 235.312 1.00 74.76  ? 623 SER C OG    1 
ATOM   7680 N N     . THR B 2 621 ? 238.901 164.096 234.379 1.00 80.33  ? 624 THR C N     1 
ATOM   7681 C CA    . THR B 2 621 ? 238.893 165.545 234.210 1.00 80.33  ? 624 THR C CA    1 
ATOM   7682 C C     . THR B 2 621 ? 237.807 165.969 233.226 1.00 80.33  ? 624 THR C C     1 
ATOM   7683 O O     . THR B 2 621 ? 237.327 167.102 233.262 1.00 80.33  ? 624 THR C O     1 
ATOM   7684 C CB    . THR B 2 621 ? 240.255 166.064 233.717 1.00 80.33  ? 624 THR C CB    1 
ATOM   7685 O OG1   . THR B 2 621 ? 240.704 165.264 232.617 1.00 80.33  ? 624 THR C OG1   1 
ATOM   7686 C CG2   . THR B 2 621 ? 241.282 166.006 234.834 1.00 80.33  ? 624 THR C CG2   1 
ATOM   7687 N N     . LYS B 2 634 ? 229.257 181.156 237.281 1.00 79.40  ? 637 LYS C N     1 
ATOM   7688 C CA    . LYS B 2 634 ? 230.211 181.813 238.166 1.00 79.40  ? 637 LYS C CA    1 
ATOM   7689 C C     . LYS B 2 634 ? 230.417 183.269 237.767 1.00 79.40  ? 637 LYS C C     1 
ATOM   7690 O O     . LYS B 2 634 ? 229.640 184.143 238.151 1.00 79.40  ? 637 LYS C O     1 
ATOM   7691 C CB    . LYS B 2 634 ? 231.549 181.072 238.157 1.00 79.40  ? 637 LYS C CB    1 
ATOM   7692 C CG    . LYS B 2 634 ? 232.263 181.094 236.815 1.00 79.40  ? 637 LYS C CG    1 
ATOM   7693 C CD    . LYS B 2 634 ? 233.244 179.941 236.687 1.00 79.40  ? 637 LYS C CD    1 
ATOM   7694 C CE    . LYS B 2 634 ? 232.523 178.614 236.523 1.00 79.40  ? 637 LYS C CE    1 
ATOM   7695 N NZ    . LYS B 2 634 ? 233.344 177.629 235.768 1.00 79.40  ? 637 LYS C NZ    1 
ATOM   7696 N N     . SER B 2 641 ? 230.853 175.285 224.346 1.00 68.18  ? 644 SER C N     1 
ATOM   7697 C CA    . SER B 2 641 ? 230.815 173.828 224.379 1.00 68.18  ? 644 SER C CA    1 
ATOM   7698 C C     . SER B 2 641 ? 230.135 173.271 223.139 1.00 68.18  ? 644 SER C C     1 
ATOM   7699 O O     . SER B 2 641 ? 230.590 172.288 222.560 1.00 68.18  ? 644 SER C O     1 
ATOM   7700 C CB    . SER B 2 641 ? 230.097 173.334 225.631 1.00 68.18  ? 644 SER C CB    1 
ATOM   7701 O OG    . SER B 2 641 ? 229.758 171.966 225.506 1.00 68.18  ? 644 SER C OG    1 
ATOM   7702 N N     . SER B 2 642 ? 229.032 173.895 222.741 1.00 66.48  ? 645 SER C N     1 
ATOM   7703 C CA    . SER B 2 642 ? 228.381 173.570 221.481 1.00 66.48  ? 645 SER C CA    1 
ATOM   7704 C C     . SER B 2 642 ? 229.030 174.271 220.299 1.00 66.48  ? 645 SER C C     1 
ATOM   7705 O O     . SER B 2 642 ? 228.524 174.169 219.177 1.00 66.48  ? 645 SER C O     1 
ATOM   7706 C CB    . SER B 2 642 ? 226.896 173.930 221.543 1.00 66.48  ? 645 SER C CB    1 
ATOM   7707 O OG    . SER B 2 642 ? 226.360 174.085 220.242 1.00 66.48  ? 645 SER C OG    1 
ATOM   7708 N N     . PHE B 2 643 ? 230.132 174.980 220.531 1.00 64.69  ? 646 PHE C N     1 
ATOM   7709 C CA    . PHE B 2 643 ? 230.856 175.695 219.493 1.00 64.69  ? 646 PHE C CA    1 
ATOM   7710 C C     . PHE B 2 643 ? 232.133 174.975 219.087 1.00 64.69  ? 646 PHE C C     1 
ATOM   7711 O O     . PHE B 2 643 ? 232.940 175.538 218.343 1.00 64.69  ? 646 PHE C O     1 
ATOM   7712 C CB    . PHE B 2 643 ? 231.191 177.114 219.962 1.00 64.69  ? 646 PHE C CB    1 
ATOM   7713 C CG    . PHE B 2 643 ? 229.993 178.012 220.120 1.00 64.69  ? 646 PHE C CG    1 
ATOM   7714 C CD1   . PHE B 2 643 ? 228.979 177.701 221.009 1.00 64.69  ? 646 PHE C CD1   1 
ATOM   7715 C CD2   . PHE B 2 643 ? 229.894 179.181 219.393 1.00 64.69  ? 646 PHE C CD2   1 
ATOM   7716 C CE1   . PHE B 2 643 ? 227.887 178.526 221.155 1.00 64.69  ? 646 PHE C CE1   1 
ATOM   7717 C CE2   . PHE B 2 643 ? 228.803 180.012 219.539 1.00 64.69  ? 646 PHE C CE2   1 
ATOM   7718 C CZ    . PHE B 2 643 ? 227.799 179.683 220.421 1.00 64.69  ? 646 PHE C CZ    1 
ATOM   7719 N N     . GLN B 2 644 ? 232.333 173.748 219.555 1.00 68.53  ? 647 GLN C N     1 
ATOM   7720 C CA    . GLN B 2 644 ? 233.566 173.026 219.290 1.00 68.53  ? 647 GLN C CA    1 
ATOM   7721 C C     . GLN B 2 644 ? 233.578 172.520 217.856 1.00 68.53  ? 647 GLN C C     1 
ATOM   7722 O O     . GLN B 2 644 ? 232.596 171.940 217.383 1.00 68.53  ? 647 GLN C O     1 
ATOM   7723 C CB    . GLN B 2 644 ? 233.722 171.861 220.264 1.00 68.53  ? 647 GLN C CB    1 
ATOM   7724 C CG    . GLN B 2 644 ? 233.819 172.280 221.716 1.00 68.53  ? 647 GLN C CG    1 
ATOM   7725 C CD    . GLN B 2 644 ? 234.873 173.340 221.944 1.00 68.53  ? 647 GLN C CD    1 
ATOM   7726 O OE1   . GLN B 2 644 ? 235.983 173.249 221.425 1.00 68.53  ? 647 GLN C OE1   1 
ATOM   7727 N NE2   . GLN B 2 644 ? 234.529 174.357 222.721 1.00 68.53  ? 647 GLN C NE2   1 
ATOM   7728 N N     . THR B 2 645 ? 234.691 172.741 217.165 1.00 65.94  ? 648 THR C N     1 
ATOM   7729 C CA    . THR B 2 645 ? 234.844 172.335 215.780 1.00 65.94  ? 648 THR C CA    1 
ATOM   7730 C C     . THR B 2 645 ? 236.158 171.588 215.615 1.00 65.94  ? 648 THR C C     1 
ATOM   7731 O O     . THR B 2 645 ? 237.079 171.722 216.423 1.00 65.94  ? 648 THR C O     1 
ATOM   7732 C CB    . THR B 2 645 ? 234.800 173.537 214.832 1.00 65.94  ? 648 THR C CB    1 
ATOM   7733 O OG1   . THR B 2 645 ? 235.733 174.529 215.271 1.00 65.94  ? 648 THR C OG1   1 
ATOM   7734 C CG2   . THR B 2 645 ? 233.411 174.142 214.805 1.00 65.94  ? 648 THR C CG2   1 
ATOM   7735 N N     . VAL B 2 646 ? 236.231 170.787 214.552 1.00 64.12  ? 649 VAL C N     1 
ATOM   7736 C CA    . VAL B 2 646 ? 237.443 170.024 214.278 1.00 64.12  ? 649 VAL C CA    1 
ATOM   7737 C C     . VAL B 2 646 ? 238.573 170.951 213.848 1.00 64.12  ? 649 VAL C C     1 
ATOM   7738 O O     . VAL B 2 646 ? 239.734 170.753 214.223 1.00 64.12  ? 649 VAL C O     1 
ATOM   7739 C CB    . VAL B 2 646 ? 237.157 168.943 213.221 1.00 64.12  ? 649 VAL C CB    1 
ATOM   7740 C CG1   . VAL B 2 646 ? 238.447 168.342 212.707 1.00 64.12  ? 649 VAL C CG1   1 
ATOM   7741 C CG2   . VAL B 2 646 ? 236.265 167.868 213.802 1.00 64.12  ? 649 VAL C CG2   1 
ATOM   7742 N N     . SER B 2 647 ? 238.252 171.986 213.073 1.00 65.51  ? 650 SER C N     1 
ATOM   7743 C CA    . SER B 2 647 ? 239.287 172.883 212.573 1.00 65.51  ? 650 SER C CA    1 
ATOM   7744 C C     . SER B 2 647 ? 239.936 173.672 213.702 1.00 65.51  ? 650 SER C C     1 
ATOM   7745 O O     . SER B 2 647 ? 241.151 173.891 213.693 1.00 65.51  ? 650 SER C O     1 
ATOM   7746 C CB    . SER B 2 647 ? 238.699 173.827 211.529 1.00 65.51  ? 650 SER C CB    1 
ATOM   7747 O OG    . SER B 2 647 ? 238.050 174.923 212.142 1.00 65.51  ? 650 SER C OG    1 
ATOM   7748 N N     . ALA B 2 648 ? 239.150 174.093 214.693 1.00 65.98  ? 651 ALA C N     1 
ATOM   7749 C CA    . ALA B 2 648 ? 239.716 174.857 215.799 1.00 65.98  ? 651 ALA C CA    1 
ATOM   7750 C C     . ALA B 2 648 ? 240.644 173.998 216.648 1.00 65.98  ? 651 ALA C C     1 
ATOM   7751 O O     . ALA B 2 648 ? 241.734 174.441 217.030 1.00 65.98  ? 651 ALA C O     1 
ATOM   7752 C CB    . ALA B 2 648 ? 238.599 175.450 216.653 1.00 65.98  ? 651 ALA C CB    1 
ATOM   7753 N N     . LEU B 2 649 ? 240.232 172.765 216.951 1.00 68.63  ? 652 LEU C N     1 
ATOM   7754 C CA    . LEU B 2 649 ? 241.097 171.865 217.706 1.00 68.63  ? 652 LEU C CA    1 
ATOM   7755 C C     . LEU B 2 649 ? 242.359 171.534 216.924 1.00 68.63  ? 652 LEU C C     1 
ATOM   7756 O O     . LEU B 2 649 ? 243.452 171.454 217.499 1.00 68.63  ? 652 LEU C O     1 
ATOM   7757 C CB    . LEU B 2 649 ? 240.344 170.588 218.065 1.00 68.63  ? 652 LEU C CB    1 
ATOM   7758 C CG    . LEU B 2 649 ? 239.183 170.773 219.039 1.00 68.63  ? 652 LEU C CG    1 
ATOM   7759 C CD1   . LEU B 2 649 ? 238.496 169.449 219.295 1.00 68.63  ? 652 LEU C CD1   1 
ATOM   7760 C CD2   . LEU B 2 649 ? 239.669 171.391 220.336 1.00 68.63  ? 652 LEU C CD2   1 
ATOM   7761 N N     . HIS B 2 650 ? 242.229 171.335 215.611 1.00 67.81  ? 653 HIS C N     1 
ATOM   7762 C CA    . HIS B 2 650 ? 243.407 171.087 214.790 1.00 67.81  ? 653 HIS C CA    1 
ATOM   7763 C C     . HIS B 2 650 ? 244.363 172.267 214.834 1.00 67.81  ? 653 HIS C C     1 
ATOM   7764 O O     . HIS B 2 650 ? 245.576 172.084 214.966 1.00 67.81  ? 653 HIS C O     1 
ATOM   7765 C CB    . HIS B 2 650 ? 243.003 170.790 213.349 1.00 67.81  ? 653 HIS C CB    1 
ATOM   7766 C CG    . HIS B 2 650 ? 244.164 170.667 212.414 1.00 67.81  ? 653 HIS C CG    1 
ATOM   7767 N ND1   . HIS B 2 650 ? 244.691 169.451 212.040 1.00 67.81  ? 653 HIS C ND1   1 
ATOM   7768 C CD2   . HIS B 2 650 ? 244.901 171.608 211.777 1.00 67.81  ? 653 HIS C CD2   1 
ATOM   7769 C CE1   . HIS B 2 650 ? 245.703 169.648 211.214 1.00 67.81  ? 653 HIS C CE1   1 
ATOM   7770 N NE2   . HIS B 2 650 ? 245.851 170.948 211.039 1.00 67.81  ? 653 HIS C NE2   1 
ATOM   7771 N N     . ARG B 2 651 ? 243.838 173.486 214.725 1.00 67.37  ? 654 ARG C N     1 
ATOM   7772 C CA    . ARG B 2 651 ? 244.702 174.660 214.749 1.00 67.37  ? 654 ARG C CA    1 
ATOM   7773 C C     . ARG B 2 651 ? 245.368 174.827 216.108 1.00 67.37  ? 654 ARG C C     1 
ATOM   7774 O O     . ARG B 2 651 ? 246.533 175.232 216.190 1.00 67.37  ? 654 ARG C O     1 
ATOM   7775 C CB    . ARG B 2 651 ? 243.901 175.905 214.381 1.00 67.37  ? 654 ARG C CB    1 
ATOM   7776 C CG    . ARG B 2 651 ? 244.690 177.192 214.453 1.00 67.37  ? 654 ARG C CG    1 
ATOM   7777 C CD    . ARG B 2 651 ? 244.078 178.270 213.579 1.00 67.37  ? 654 ARG C CD    1 
ATOM   7778 N NE    . ARG B 2 651 ? 242.729 178.632 213.999 1.00 67.37  ? 654 ARG C NE    1 
ATOM   7779 C CZ    . ARG B 2 651 ? 241.623 178.220 213.390 1.00 67.37  ? 654 ARG C CZ    1 
ATOM   7780 N NH1   . ARG B 2 651 ? 241.705 177.428 212.331 1.00 67.37  ? 654 ARG C NH1   1 
ATOM   7781 N NH2   . ARG B 2 651 ? 240.436 178.599 213.840 1.00 67.37  ? 654 ARG C NH2   1 
ATOM   7782 N N     . GLU B 2 652 ? 244.657 174.495 217.185 1.00 69.92  ? 655 GLU C N     1 
ATOM   7783 C CA    . GLU B 2 652 ? 245.249 174.589 218.515 1.00 69.92  ? 655 GLU C CA    1 
ATOM   7784 C C     . GLU B 2 652 ? 246.378 173.579 218.688 1.00 69.92  ? 655 GLU C C     1 
ATOM   7785 O O     . GLU B 2 652 ? 247.467 173.921 219.172 1.00 69.92  ? 655 GLU C O     1 
ATOM   7786 C CB    . GLU B 2 652 ? 244.170 174.388 219.577 1.00 69.92  ? 655 GLU C CB    1 
ATOM   7787 C CG    . GLU B 2 652 ? 244.655 174.556 221.001 1.00 69.92  ? 655 GLU C CG    1 
ATOM   7788 C CD    . GLU B 2 652 ? 243.542 174.371 222.012 1.00 69.92  ? 655 GLU C CD    1 
ATOM   7789 O OE1   . GLU B 2 652 ? 242.368 174.300 221.594 1.00 69.92  ? 655 GLU C OE1   1 
ATOM   7790 O OE2   . GLU B 2 652 ? 243.840 174.297 223.223 1.00 69.92  ? 655 GLU C OE2   1 
ATOM   7791 N N     . ASN B 2 653 ? 246.142 172.325 218.293 1.00 67.89  ? 656 ASN C N     1 
ATOM   7792 C CA    . ASN B 2 653 ? 247.201 171.324 218.373 1.00 67.89  ? 656 ASN C CA    1 
ATOM   7793 C C     . ASN B 2 653 ? 248.375 171.670 217.468 1.00 67.89  ? 656 ASN C C     1 
ATOM   7794 O O     . ASN B 2 653 ? 249.526 171.381 217.808 1.00 67.89  ? 656 ASN C O     1 
ATOM   7795 C CB    . ASN B 2 653 ? 246.653 169.944 218.022 1.00 67.89  ? 656 ASN C CB    1 
ATOM   7796 C CG    . ASN B 2 653 ? 245.417 169.597 218.810 1.00 67.89  ? 656 ASN C CG    1 
ATOM   7797 O OD1   . ASN B 2 653 ? 245.132 170.211 219.835 1.00 67.89  ? 656 ASN C OD1   1 
ATOM   7798 N ND2   . ASN B 2 653 ? 244.671 168.609 218.336 1.00 67.89  ? 656 ASN C ND2   1 
ATOM   7799 N N     . LEU B 2 654 ? 248.111 172.298 216.322 1.00 66.82  ? 657 LEU C N     1 
ATOM   7800 C CA    . LEU B 2 654 ? 249.199 172.700 215.441 1.00 66.82  ? 657 LEU C CA    1 
ATOM   7801 C C     . LEU B 2 654 ? 250.024 173.817 216.063 1.00 66.82  ? 657 LEU C C     1 
ATOM   7802 O O     . LEU B 2 654 ? 251.254 173.818 215.957 1.00 66.82  ? 657 LEU C O     1 
ATOM   7803 C CB    . LEU B 2 654 ? 248.645 173.132 214.087 1.00 66.82  ? 657 LEU C CB    1 
ATOM   7804 C CG    . LEU B 2 654 ? 249.675 173.390 212.991 1.00 66.82  ? 657 LEU C CG    1 
ATOM   7805 C CD1   . LEU B 2 654 ? 250.717 172.296 212.974 1.00 66.82  ? 657 LEU C CD1   1 
ATOM   7806 C CD2   . LEU B 2 654 ? 248.982 173.472 211.658 1.00 66.82  ? 657 LEU C CD2   1 
ATOM   7807 N N     . ASN B 2 655 ? 249.365 174.781 216.707 1.00 68.08  ? 658 ASN C N     1 
ATOM   7808 C CA    . ASN B 2 655 ? 250.101 175.803 217.440 1.00 68.08  ? 658 ASN C CA    1 
ATOM   7809 C C     . ASN B 2 655 ? 250.961 175.178 218.527 1.00 68.08  ? 658 ASN C C     1 
ATOM   7810 O O     . ASN B 2 655 ? 252.115 175.576 218.723 1.00 68.08  ? 658 ASN C O     1 
ATOM   7811 C CB    . ASN B 2 655 ? 249.137 176.821 218.045 1.00 68.08  ? 658 ASN C CB    1 
ATOM   7812 C CG    . ASN B 2 655 ? 248.644 177.826 217.032 1.00 68.08  ? 658 ASN C CG    1 
ATOM   7813 O OD1   . ASN B 2 655 ? 249.275 178.046 216.000 1.00 68.08  ? 658 ASN C OD1   1 
ATOM   7814 N ND2   . ASN B 2 655 ? 247.507 178.446 217.322 1.00 68.08  ? 658 ASN C ND2   1 
ATOM   7815 N N     . LYS B 2 656 ? 250.422 174.184 219.233 1.00 67.21  ? 659 LYS C N     1 
ATOM   7816 C CA    . LYS B 2 656 ? 251.190 173.532 220.290 1.00 67.21  ? 659 LYS C CA    1 
ATOM   7817 C C     . LYS B 2 656 ? 252.413 172.818 219.723 1.00 67.21  ? 659 LYS C C     1 
ATOM   7818 O O     . LYS B 2 656 ? 253.521 172.928 220.264 1.00 67.21  ? 659 LYS C O     1 
ATOM   7819 C CB    . LYS B 2 656 ? 250.298 172.556 221.054 1.00 67.21  ? 659 LYS C CB    1 
ATOM   7820 C CG    . LYS B 2 656 ? 251.056 171.574 221.923 1.00 67.21  ? 659 LYS C CG    1 
ATOM   7821 C CD    . LYS B 2 656 ? 250.163 170.983 222.997 1.00 67.21  ? 659 LYS C CD    1 
ATOM   7822 C CE    . LYS B 2 656 ? 248.816 170.574 222.430 1.00 67.21  ? 659 LYS C CE    1 
ATOM   7823 N NZ    . LYS B 2 656 ? 247.942 169.957 223.464 1.00 67.21  ? 659 LYS C NZ    1 
ATOM   7824 N N     . LEU B 2 657 ? 252.231 172.086 218.623 1.00 65.26  ? 660 LEU C N     1 
ATOM   7825 C CA    . LEU B 2 657 ? 253.352 171.384 218.005 1.00 65.26  ? 660 LEU C CA    1 
ATOM   7826 C C     . LEU B 2 657 ? 254.414 172.356 217.507 1.00 65.26  ? 660 LEU C C     1 
ATOM   7827 O O     . LEU B 2 657 ? 255.615 172.130 217.700 1.00 65.26  ? 660 LEU C O     1 
ATOM   7828 C CB    . LEU B 2 657 ? 252.852 170.509 216.858 1.00 65.26  ? 660 LEU C CB    1 
ATOM   7829 C CG    . LEU B 2 657 ? 253.922 169.791 216.042 1.00 65.26  ? 660 LEU C CG    1 
ATOM   7830 C CD1   . LEU B 2 657 ? 254.629 168.766 216.897 1.00 65.26  ? 660 LEU C CD1   1 
ATOM   7831 C CD2   . LEU B 2 657 ? 253.304 169.137 214.825 1.00 65.26  ? 660 LEU C CD2   1 
ATOM   7832 N N     . MET B 2 658 ? 253.993 173.443 216.859 1.00 67.25  ? 661 MET C N     1 
ATOM   7833 C CA    . MET B 2 658 ? 254.957 174.413 216.356 1.00 67.25  ? 661 MET C CA    1 
ATOM   7834 C C     . MET B 2 658 ? 255.694 175.098 217.496 1.00 67.25  ? 661 MET C C     1 
ATOM   7835 O O     . MET B 2 658 ? 256.883 175.409 217.373 1.00 67.25  ? 661 MET C O     1 
ATOM   7836 C CB    . MET B 2 658 ? 254.261 175.440 215.468 1.00 67.25  ? 661 MET C CB    1 
ATOM   7837 C CG    . MET B 2 658 ? 253.771 174.877 214.148 1.00 67.25  ? 661 MET C CG    1 
ATOM   7838 S SD    . MET B 2 658 ? 255.005 173.873 213.304 1.00 67.25  ? 661 MET C SD    1 
ATOM   7839 C CE    . MET B 2 658 ? 256.331 175.057 213.091 1.00 67.25  ? 661 MET C CE    1 
ATOM   7840 N N     . THR B 2 659 ? 255.013 175.331 218.619 1.00 67.91  ? 662 THR C N     1 
ATOM   7841 C CA    . THR B 2 659 ? 255.685 175.928 219.766 1.00 67.91  ? 662 THR C CA    1 
ATOM   7842 C C     . THR B 2 659 ? 256.705 174.967 220.362 1.00 67.91  ? 662 THR C C     1 
ATOM   7843 O O     . THR B 2 659 ? 257.793 175.387 220.770 1.00 67.91  ? 662 THR C O     1 
ATOM   7844 C CB    . THR B 2 659 ? 254.657 176.351 220.813 1.00 67.91  ? 662 THR C CB    1 
ATOM   7845 O OG1   . THR B 2 659 ? 253.911 177.468 220.318 1.00 67.91  ? 662 THR C OG1   1 
ATOM   7846 C CG2   . THR B 2 659 ? 255.338 176.750 222.105 1.00 67.91  ? 662 THR C CG2   1 
ATOM   7847 N N     . ASN B 2 660 ? 256.380 173.674 220.412 1.00 69.13  ? 663 ASN C N     1 
ATOM   7848 C CA    . ASN B 2 660 ? 257.377 172.699 220.845 1.00 69.13  ? 663 ASN C CA    1 
ATOM   7849 C C     . ASN B 2 660 ? 258.578 172.685 219.909 1.00 69.13  ? 663 ASN C C     1 
ATOM   7850 O O     . ASN B 2 660 ? 259.726 172.607 220.362 1.00 69.13  ? 663 ASN C O     1 
ATOM   7851 C CB    . ASN B 2 660 ? 256.766 171.304 220.944 1.00 69.13  ? 663 ASN C CB    1 
ATOM   7852 C CG    . ASN B 2 660 ? 255.788 171.179 222.088 1.00 69.13  ? 663 ASN C CG    1 
ATOM   7853 O OD1   . ASN B 2 660 ? 254.599 170.947 221.884 1.00 69.13  ? 663 ASN C OD1   1 
ATOM   7854 N ND2   . ASN B 2 660 ? 256.288 171.334 223.307 1.00 69.13  ? 663 ASN C ND2   1 
ATOM   7855 N N     . LEU B 2 661 ? 258.336 172.764 218.600 1.00 65.74  ? 664 LEU C N     1 
ATOM   7856 C CA    . LEU B 2 661 ? 259.434 172.654 217.642 1.00 65.74  ? 664 LEU C CA    1 
ATOM   7857 C C     . LEU B 2 661 ? 260.314 173.897 217.637 1.00 65.74  ? 664 LEU C C     1 
ATOM   7858 O O     . LEU B 2 661 ? 261.533 173.795 217.464 1.00 65.74  ? 664 LEU C O     1 
ATOM   7859 C CB    . LEU B 2 661 ? 258.887 172.394 216.241 1.00 65.74  ? 664 LEU C CB    1 
ATOM   7860 C CG    . LEU B 2 661 ? 258.303 171.011 215.988 1.00 65.74  ? 664 LEU C CG    1 
ATOM   7861 C CD1   . LEU B 2 661 ? 257.479 171.027 214.725 1.00 65.74  ? 664 LEU C CD1   1 
ATOM   7862 C CD2   . LEU B 2 661 ? 259.418 169.997 215.891 1.00 65.74  ? 664 LEU C CD2   1 
ATOM   7863 N N     . LYS B 2 662 ? 259.724 175.079 217.820 1.00 67.90  ? 665 LYS C N     1 
ATOM   7864 C CA    . LYS B 2 662 ? 260.478 176.319 217.673 1.00 67.90  ? 665 LYS C CA    1 
ATOM   7865 C C     . LYS B 2 662 ? 261.493 176.543 218.784 1.00 67.90  ? 665 LYS C C     1 
ATOM   7866 O O     . LYS B 2 662 ? 262.368 177.400 218.631 1.00 67.90  ? 665 LYS C O     1 
ATOM   7867 C CB    . LYS B 2 662 ? 259.523 177.510 217.606 1.00 67.90  ? 665 LYS C CB    1 
ATOM   7868 C CG    . LYS B 2 662 ? 258.870 177.696 216.249 1.00 67.90  ? 665 LYS C CG    1 
ATOM   7869 C CD    . LYS B 2 662 ? 257.992 178.931 216.216 1.00 67.90  ? 665 LYS C CD    1 
ATOM   7870 C CE    . LYS B 2 662 ? 257.302 179.067 214.872 1.00 67.90  ? 665 LYS C CE    1 
ATOM   7871 N NZ    . LYS B 2 662 ? 256.271 180.140 214.880 1.00 67.90  ? 665 LYS C NZ    1 
ATOM   7872 N N     . THR B 2 663 ? 261.404 175.806 219.885 1.00 70.21  ? 666 THR C N     1 
ATOM   7873 C CA    . THR B 2 663 ? 262.367 175.914 220.971 1.00 70.21  ? 666 THR C CA    1 
ATOM   7874 C C     . THR B 2 663 ? 263.562 174.989 220.785 1.00 70.21  ? 666 THR C C     1 
ATOM   7875 O O     . THR B 2 663 ? 264.351 174.821 221.718 1.00 70.21  ? 666 THR C O     1 
ATOM   7876 C CB    . THR B 2 663 ? 261.691 175.613 222.309 1.00 70.21  ? 666 THR C CB    1 
ATOM   7877 O OG1   . THR B 2 663 ? 261.363 174.220 222.375 1.00 70.21  ? 666 THR C OG1   1 
ATOM   7878 C CG2   . THR B 2 663 ? 260.422 176.431 222.456 1.00 70.21  ? 666 THR C CG2   1 
ATOM   7879 N N     . THR B 2 664 ? 263.709 174.390 219.611 1.00 69.30  ? 667 THR C N     1 
ATOM   7880 C CA    . THR B 2 664 ? 264.739 173.398 219.349 1.00 69.30  ? 667 THR C CA    1 
ATOM   7881 C C     . THR B 2 664 ? 265.620 173.860 218.190 1.00 69.30  ? 667 THR C C     1 
ATOM   7882 O O     . THR B 2 664 ? 265.507 174.985 217.700 1.00 69.30  ? 667 THR C O     1 
ATOM   7883 C CB    . THR B 2 664 ? 264.103 172.041 219.046 1.00 69.30  ? 667 THR C CB    1 
ATOM   7884 O OG1   . THR B 2 664 ? 263.020 172.220 218.127 1.00 69.30  ? 667 THR C OG1   1 
ATOM   7885 C CG2   . THR B 2 664 ? 263.565 171.411 220.307 1.00 69.30  ? 667 THR C CG2   1 
ATOM   7886 N N     . HIS B 2 665 ? 266.506 172.972 217.760 1.00 69.63  ? 668 HIS C N     1 
ATOM   7887 C CA    . HIS B 2 665 ? 267.346 173.191 216.585 1.00 69.63  ? 668 HIS C CA    1 
ATOM   7888 C C     . HIS B 2 665 ? 267.094 172.052 215.612 1.00 69.63  ? 668 HIS C C     1 
ATOM   7889 O O     . HIS B 2 665 ? 267.533 170.915 215.868 1.00 69.63  ? 668 HIS C O     1 
ATOM   7890 C CB    . HIS B 2 665 ? 268.820 173.258 216.977 1.00 69.63  ? 668 HIS C CB    1 
ATOM   7891 C CG    . HIS B 2 665 ? 269.716 173.745 215.886 1.00 69.63  ? 668 HIS C CG    1 
ATOM   7892 N ND1   . HIS B 2 665 ? 270.290 172.901 214.962 1.00 69.63  ? 668 HIS C ND1   1 
ATOM   7893 C CD2   . HIS B 2 665 ? 270.144 174.990 215.574 1.00 69.63  ? 668 HIS C CD2   1 
ATOM   7894 C CE1   . HIS B 2 665 ? 271.030 173.605 214.125 1.00 69.63  ? 668 HIS C CE1   1 
ATOM   7895 N NE2   . HIS B 2 665 ? 270.958 174.876 214.474 1.00 69.63  ? 668 HIS C NE2   1 
ATOM   7896 N N     . PRO B 2 666 ? 266.403 172.287 214.503 1.00 66.51  ? 669 PRO C N     1 
ATOM   7897 C CA    . PRO B 2 666 ? 265.935 171.182 213.664 1.00 66.51  ? 669 PRO C CA    1 
ATOM   7898 C C     . PRO B 2 666 ? 266.963 170.686 212.662 1.00 66.51  ? 669 PRO C C     1 
ATOM   7899 O O     . PRO B 2 666 ? 267.792 171.433 212.143 1.00 66.51  ? 669 PRO C O     1 
ATOM   7900 C CB    . PRO B 2 666 ? 264.738 171.805 212.935 1.00 66.51  ? 669 PRO C CB    1 
ATOM   7901 C CG    . PRO B 2 666 ? 265.099 173.227 212.822 1.00 66.51  ? 669 PRO C CG    1 
ATOM   7902 C CD    . PRO B 2 666 ? 265.840 173.576 214.076 1.00 66.51  ? 669 PRO C CD    1 
ATOM   7903 N N     . HIS B 2 667 ? 266.885 169.384 212.397 1.00 66.29  ? 670 HIS C N     1 
ATOM   7904 C CA    . HIS B 2 667 ? 267.642 168.734 211.335 1.00 66.29  ? 670 HIS C CA    1 
ATOM   7905 C C     . HIS B 2 667 ? 266.660 167.905 210.526 1.00 66.29  ? 670 HIS C C     1 
ATOM   7906 O O     . HIS B 2 667 ? 265.840 167.186 211.101 1.00 66.29  ? 670 HIS C O     1 
ATOM   7907 C CB    . HIS B 2 667 ? 268.760 167.856 211.898 1.00 66.29  ? 670 HIS C CB    1 
ATOM   7908 C CG    . HIS B 2 667 ? 269.624 168.550 212.903 1.00 66.29  ? 670 HIS C CG    1 
ATOM   7909 N ND1   . HIS B 2 667 ? 270.657 169.388 212.546 1.00 66.29  ? 670 HIS C ND1   1 
ATOM   7910 C CD2   . HIS B 2 667 ? 269.609 168.529 214.256 1.00 66.29  ? 670 HIS C CD2   1 
ATOM   7911 C CE1   . HIS B 2 667 ? 271.239 169.855 213.635 1.00 66.29  ? 670 HIS C CE1   1 
ATOM   7912 N NE2   . HIS B 2 667 ? 270.622 169.349 214.686 1.00 66.29  ? 670 HIS C NE2   1 
ATOM   7913 N N     . PHE B 2 668 ? 266.731 168.007 209.205 1.00 62.49  ? 671 PHE C N     1 
ATOM   7914 C CA    . PHE B 2 668 ? 265.703 167.454 208.337 1.00 62.49  ? 671 PHE C CA    1 
ATOM   7915 C C     . PHE B 2 668 ? 266.224 166.259 207.550 1.00 62.49  ? 671 PHE C C     1 
ATOM   7916 O O     . PHE B 2 668 ? 267.344 166.277 207.037 1.00 62.49  ? 671 PHE C O     1 
ATOM   7917 C CB    . PHE B 2 668 ? 265.182 168.527 207.384 1.00 62.49  ? 671 PHE C CB    1 
ATOM   7918 C CG    . PHE B 2 668 ? 264.683 169.760 208.079 1.00 62.49  ? 671 PHE C CG    1 
ATOM   7919 C CD1   . PHE B 2 668 ? 263.338 169.927 208.335 1.00 62.49  ? 671 PHE C CD1   1 
ATOM   7920 C CD2   . PHE B 2 668 ? 265.558 170.752 208.476 1.00 62.49  ? 671 PHE C CD2   1 
ATOM   7921 C CE1   . PHE B 2 668 ? 262.878 171.056 208.974 1.00 62.49  ? 671 PHE C CE1   1 
ATOM   7922 C CE2   . PHE B 2 668 ? 265.101 171.881 209.119 1.00 62.49  ? 671 PHE C CE2   1 
ATOM   7923 C CZ    . PHE B 2 668 ? 263.761 172.032 209.366 1.00 62.49  ? 671 PHE C CZ    1 
ATOM   7924 N N     . VAL B 2 669 ? 265.394 165.223 207.458 1.00 62.22  ? 672 VAL C N     1 
ATOM   7925 C CA    . VAL B 2 669 ? 265.694 164.006 206.713 1.00 62.22  ? 672 VAL C CA    1 
ATOM   7926 C C     . VAL B 2 669 ? 264.535 163.740 205.765 1.00 62.22  ? 672 VAL C C     1 
ATOM   7927 O O     . VAL B 2 669 ? 263.373 163.966 206.119 1.00 62.22  ? 672 VAL C O     1 
ATOM   7928 C CB    . VAL B 2 669 ? 265.919 162.806 207.656 1.00 62.22  ? 672 VAL C CB    1 
ATOM   7929 C CG1   . VAL B 2 669 ? 266.154 161.531 206.869 1.00 62.22  ? 672 VAL C CG1   1 
ATOM   7930 C CG2   . VAL B 2 669 ? 267.080 163.080 208.585 1.00 62.22  ? 672 VAL C CG2   1 
ATOM   7931 N N     . ARG B 2 670 ? 264.844 163.264 204.560 1.00 65.38  ? 673 ARG C N     1 
ATOM   7932 C CA    . ARG B 2 670 ? 263.847 163.096 203.504 1.00 65.38  ? 673 ARG C CA    1 
ATOM   7933 C C     . ARG B 2 670 ? 264.036 161.740 202.834 1.00 65.38  ? 673 ARG C C     1 
ATOM   7934 O O     . ARG B 2 670 ? 264.865 161.600 201.933 1.00 65.38  ? 673 ARG C O     1 
ATOM   7935 C CB    . ARG B 2 670 ? 263.947 164.225 202.488 1.00 65.38  ? 673 ARG C CB    1 
ATOM   7936 C CG    . ARG B 2 670 ? 263.538 165.575 203.033 1.00 65.38  ? 673 ARG C CG    1 
ATOM   7937 C CD    . ARG B 2 670 ? 262.133 165.529 203.589 1.00 65.38  ? 673 ARG C CD    1 
ATOM   7938 N NE    . ARG B 2 670 ? 261.677 166.836 204.046 1.00 65.38  ? 673 ARG C NE    1 
ATOM   7939 C CZ    . ARG B 2 670 ? 261.538 167.174 205.322 1.00 65.38  ? 673 ARG C CZ    1 
ATOM   7940 N NH1   . ARG B 2 670 ? 261.817 166.298 206.274 1.00 65.38  ? 673 ARG C NH1   1 
ATOM   7941 N NH2   . ARG B 2 670 ? 261.116 168.385 205.645 1.00 65.38  ? 673 ARG C NH2   1 
ATOM   7942 N N     . CYS B 2 671 ? 263.260 160.749 203.261 1.00 71.36  ? 674 CYS C N     1 
ATOM   7943 C CA    . CYS B 2 671 ? 263.304 159.432 202.644 1.00 71.36  ? 674 CYS C CA    1 
ATOM   7944 C C     . CYS B 2 671 ? 262.447 159.411 201.386 1.00 71.36  ? 674 CYS C C     1 
ATOM   7945 O O     . CYS B 2 671 ? 261.416 160.084 201.309 1.00 71.36  ? 674 CYS C O     1 
ATOM   7946 C CB    . CYS B 2 671 ? 262.824 158.367 203.626 1.00 71.36  ? 674 CYS C CB    1 
ATOM   7947 S SG    . CYS B 2 671 ? 263.514 158.534 205.280 1.00 71.36  ? 674 CYS C SG    1 
ATOM   7948 N N     . ILE B 2 672 ? 262.874 158.626 200.400 1.00 72.50  ? 675 ILE C N     1 
ATOM   7949 C CA    . ILE B 2 672 ? 262.279 158.641 199.070 1.00 72.50  ? 675 ILE C CA    1 
ATOM   7950 C C     . ILE B 2 672 ? 262.029 157.214 198.606 1.00 72.50  ? 675 ILE C C     1 
ATOM   7951 O O     . ILE B 2 672 ? 262.898 156.346 198.734 1.00 72.50  ? 675 ILE C O     1 
ATOM   7952 C CB    . ILE B 2 672 ? 263.180 159.391 198.067 1.00 72.50  ? 675 ILE C CB    1 
ATOM   7953 C CG1   . ILE B 2 672 ? 263.091 160.897 198.300 1.00 72.50  ? 675 ILE C CG1   1 
ATOM   7954 C CG2   . ILE B 2 672 ? 262.801 159.054 196.639 1.00 72.50  ? 675 ILE C CG2   1 
ATOM   7955 C CD1   . ILE B 2 672 ? 263.724 161.717 197.212 1.00 72.50  ? 675 ILE C CD1   1 
ATOM   7956 N N     . ILE B 2 673 ? 260.838 156.976 198.067 1.00 78.41  ? 676 ILE C N     1 
ATOM   7957 C CA    . ILE B 2 673 ? 260.491 155.701 197.448 1.00 78.41  ? 676 ILE C CA    1 
ATOM   7958 C C     . ILE B 2 673 ? 260.878 155.781 195.975 1.00 78.41  ? 676 ILE C C     1 
ATOM   7959 O O     . ILE B 2 673 ? 260.273 156.571 195.234 1.00 78.41  ? 676 ILE C O     1 
ATOM   7960 C CB    . ILE B 2 673 ? 258.998 155.391 197.600 1.00 78.41  ? 676 ILE C CB    1 
ATOM   7961 C CG1   . ILE B 2 673 ? 258.537 155.643 199.035 1.00 78.41  ? 676 ILE C CG1   1 
ATOM   7962 C CG2   . ILE B 2 673 ? 258.703 153.966 197.179 1.00 78.41  ? 676 ILE C CG2   1 
ATOM   7963 C CD1   . ILE B 2 673 ? 259.270 154.817 200.071 1.00 78.41  ? 676 ILE C CD1   1 
ATOM   7964 N N     . PRO B 2 674 ? 261.852 154.995 195.511 1.00 83.06  ? 677 PRO C N     1 
ATOM   7965 C CA    . PRO B 2 674 ? 262.300 155.158 194.121 1.00 83.06  ? 677 PRO C CA    1 
ATOM   7966 C C     . PRO B 2 674 ? 261.307 154.631 193.102 1.00 83.06  ? 677 PRO C C     1 
ATOM   7967 O O     . PRO B 2 674 ? 261.124 155.253 192.049 1.00 83.06  ? 677 PRO C O     1 
ATOM   7968 C CB    . PRO B 2 674 ? 263.619 154.379 194.098 1.00 83.06  ? 677 PRO C CB    1 
ATOM   7969 C CG    . PRO B 2 674 ? 263.428 153.322 195.116 1.00 83.06  ? 677 PRO C CG    1 
ATOM   7970 C CD    . PRO B 2 674 ? 262.588 153.928 196.207 1.00 83.06  ? 677 PRO C CD    1 
ATOM   7971 N N     . ASN B 2 675 ? 260.657 153.506 193.381 1.00 88.60  ? 678 ASN C N     1 
ATOM   7972 C CA    . ASN B 2 675 ? 259.675 152.942 192.468 1.00 88.60  ? 678 ASN C CA    1 
ATOM   7973 C C     . ASN B 2 675 ? 258.643 152.172 193.277 1.00 88.60  ? 678 ASN C C     1 
ATOM   7974 O O     . ASN B 2 675 ? 258.777 151.997 194.489 1.00 88.60  ? 678 ASN C O     1 
ATOM   7975 C CB    . ASN B 2 675 ? 260.337 152.041 191.424 1.00 88.60  ? 678 ASN C CB    1 
ATOM   7976 C CG    . ASN B 2 675 ? 261.050 150.862 192.044 1.00 88.60  ? 678 ASN C CG    1 
ATOM   7977 O OD1   . ASN B 2 675 ? 261.537 150.940 193.169 1.00 88.60  ? 678 ASN C OD1   1 
ATOM   7978 N ND2   . ASN B 2 675 ? 261.114 149.760 191.313 1.00 88.60  ? 678 ASN C ND2   1 
ATOM   7979 N N     . GLU B 2 676 ? 257.605 151.704 192.587 1.00 93.23  ? 679 GLU C N     1 
ATOM   7980 C CA    . GLU B 2 676 ? 256.500 151.022 193.247 1.00 93.23  ? 679 GLU C CA    1 
ATOM   7981 C C     . GLU B 2 676 ? 256.603 149.505 193.198 1.00 93.23  ? 679 GLU C C     1 
ATOM   7982 O O     . GLU B 2 676 ? 255.961 148.834 194.013 1.00 93.23  ? 679 GLU C O     1 
ATOM   7983 C CB    . GLU B 2 676 ? 255.164 151.451 192.627 1.00 93.23  ? 679 GLU C CB    1 
ATOM   7984 C CG    . GLU B 2 676 ? 254.859 150.808 191.280 1.00 93.23  ? 679 GLU C CG    1 
ATOM   7985 C CD    . GLU B 2 676 ? 255.663 151.405 190.140 1.00 93.23  ? 679 GLU C CD    1 
ATOM   7986 O OE1   . GLU B 2 676 ? 256.316 152.449 190.350 1.00 93.23  ? 679 GLU C OE1   1 
ATOM   7987 O OE2   . GLU B 2 676 ? 255.640 150.829 189.032 1.00 93.23  ? 679 GLU C OE2   1 
ATOM   7988 N N     . ARG B 2 677 ? 257.384 148.949 192.273 1.00 93.04  ? 680 ARG C N     1 
ATOM   7989 C CA    . ARG B 2 677 ? 257.506 147.506 192.122 1.00 93.04  ? 680 ARG C CA    1 
ATOM   7990 C C     . ARG B 2 677 ? 258.687 146.929 192.895 1.00 93.04  ? 680 ARG C C     1 
ATOM   7991 O O     . ARG B 2 677 ? 259.110 145.804 192.608 1.00 93.04  ? 680 ARG C O     1 
ATOM   7992 C CB    . ARG B 2 677 ? 257.613 147.137 190.640 1.00 93.04  ? 680 ARG C CB    1 
ATOM   7993 C CG    . ARG B 2 677 ? 258.809 147.739 189.929 1.00 93.04  ? 680 ARG C CG    1 
ATOM   7994 C CD    . ARG B 2 677 ? 258.553 147.854 188.438 1.00 93.04  ? 680 ARG C CD    1 
ATOM   7995 N NE    . ARG B 2 677 ? 259.657 148.503 187.739 1.00 93.04  ? 680 ARG C NE    1 
ATOM   7996 C CZ    . ARG B 2 677 ? 259.814 149.819 187.645 1.00 93.04  ? 680 ARG C CZ    1 
ATOM   7997 N NH1   . ARG B 2 677 ? 258.939 150.638 188.209 1.00 93.04  ? 680 ARG C NH1   1 
ATOM   7998 N NH2   . ARG B 2 677 ? 260.850 150.318 186.986 1.00 93.04  ? 680 ARG C NH2   1 
ATOM   7999 N N     . LYS B 2 678 ? 259.233 147.678 193.852 1.00 90.80  ? 681 LYS C N     1 
ATOM   8000 C CA    . LYS B 2 678 ? 260.279 147.235 194.771 1.00 90.80  ? 681 LYS C CA    1 
ATOM   8001 C C     . LYS B 2 678 ? 261.597 146.911 194.081 1.00 90.80  ? 681 LYS C C     1 
ATOM   8002 O O     . LYS B 2 678 ? 262.503 146.372 194.727 1.00 90.80  ? 681 LYS C O     1 
ATOM   8003 C CB    . LYS B 2 678 ? 259.834 146.017 195.589 1.00 90.80  ? 681 LYS C CB    1 
ATOM   8004 C CG    . LYS B 2 678 ? 258.591 146.245 196.424 1.00 90.80  ? 681 LYS C CG    1 
ATOM   8005 C CD    . LYS B 2 678 ? 258.876 147.156 197.600 1.00 90.80  ? 681 LYS C CD    1 
ATOM   8006 C CE    . LYS B 2 678 ? 258.016 146.787 198.795 1.00 90.80  ? 681 LYS C CE    1 
ATOM   8007 N NZ    . LYS B 2 678 ? 258.378 147.575 200.005 1.00 90.80  ? 681 LYS C NZ    1 
ATOM   8008 N N     . ALA B 2 679 ? 261.739 147.220 192.801 1.00 92.17  ? 682 ALA C N     1 
ATOM   8009 C CA    . ALA B 2 679 ? 262.958 146.869 192.079 1.00 92.17  ? 682 ALA C CA    1 
ATOM   8010 C C     . ALA B 2 679 ? 264.111 147.759 192.521 1.00 92.17  ? 682 ALA C C     1 
ATOM   8011 O O     . ALA B 2 679 ? 264.042 148.981 192.338 1.00 92.17  ? 682 ALA C O     1 
ATOM   8012 C CB    . ALA B 2 679 ? 262.741 146.993 190.575 1.00 92.17  ? 682 ALA C CB    1 
ATOM   8013 N N     . PRO B 2 680 ? 265.175 147.206 193.097 1.00 90.86  ? 683 PRO C N     1 
ATOM   8014 C CA    . PRO B 2 680 ? 266.299 148.043 193.523 1.00 90.86  ? 683 PRO C CA    1 
ATOM   8015 C C     . PRO B 2 680 ? 267.117 148.534 192.344 1.00 90.86  ? 683 PRO C C     1 
ATOM   8016 O O     . PRO B 2 680 ? 267.289 147.839 191.341 1.00 90.86  ? 683 PRO C O     1 
ATOM   8017 C CB    . PRO B 2 680 ? 267.121 147.101 194.407 1.00 90.86  ? 683 PRO C CB    1 
ATOM   8018 C CG    . PRO B 2 680 ? 266.805 145.749 193.891 1.00 90.86  ? 683 PRO C CG    1 
ATOM   8019 C CD    . PRO B 2 680 ? 265.364 145.797 193.477 1.00 90.86  ? 683 PRO C CD    1 
ATOM   8020 N N     . GLY B 2 681 ? 267.628 149.755 192.477 1.00 91.16  ? 684 GLY C N     1 
ATOM   8021 C CA    . GLY B 2 681 ? 268.544 150.298 191.495 1.00 91.16  ? 684 GLY C CA    1 
ATOM   8022 C C     . GLY B 2 681 ? 267.917 151.244 190.492 1.00 91.16  ? 684 GLY C C     1 
ATOM   8023 O O     . GLY B 2 681 ? 268.565 152.194 190.043 1.00 91.16  ? 684 GLY C O     1 
ATOM   8024 N N     . VAL B 2 682 ? 266.661 150.999 190.130 1.00 91.48  ? 685 VAL C N     1 
ATOM   8025 C CA    . VAL B 2 682 ? 265.962 151.785 189.122 1.00 91.48  ? 685 VAL C CA    1 
ATOM   8026 C C     . VAL B 2 682 ? 264.801 152.511 189.785 1.00 91.48  ? 685 VAL C C     1 
ATOM   8027 O O     . VAL B 2 682 ? 264.106 151.947 190.637 1.00 91.48  ? 685 VAL C O     1 
ATOM   8028 C CB    . VAL B 2 682 ? 265.475 150.900 187.955 1.00 91.48  ? 685 VAL C CB    1 
ATOM   8029 C CG1   . VAL B 2 682 ? 264.607 149.760 188.470 1.00 91.48  ? 685 VAL C CG1   1 
ATOM   8030 C CG2   . VAL B 2 682 ? 264.730 151.731 186.923 1.00 91.48  ? 685 VAL C CG2   1 
ATOM   8031 N N     . MET B 2 683 ? 264.601 153.769 189.401 1.00 90.84  ? 686 MET C N     1 
ATOM   8032 C CA    . MET B 2 683 ? 263.559 154.610 189.967 1.00 90.84  ? 686 MET C CA    1 
ATOM   8033 C C     . MET B 2 683 ? 262.712 155.221 188.861 1.00 90.84  ? 686 MET C C     1 
ATOM   8034 O O     . MET B 2 683 ? 263.222 155.557 187.789 1.00 90.84  ? 686 MET C O     1 
ATOM   8035 C CB    . MET B 2 683 ? 264.159 155.720 190.826 1.00 90.84  ? 686 MET C CB    1 
ATOM   8036 C CG    . MET B 2 683 ? 265.389 156.366 190.228 1.00 90.84  ? 686 MET C CG    1 
ATOM   8037 S SD    . MET B 2 683 ? 265.930 157.784 191.194 1.00 90.84  ? 686 MET C SD    1 
ATOM   8038 C CE    . MET B 2 683 ? 264.969 159.081 190.430 1.00 90.84  ? 686 MET C CE    1 
ATOM   8039 N N     . ASP B 2 684 ? 261.419 155.369 189.136 1.00 90.73  ? 687 ASP C N     1 
ATOM   8040 C CA    . ASP B 2 684 ? 260.491 155.992 188.203 1.00 90.73  ? 687 ASP C CA    1 
ATOM   8041 C C     . ASP B 2 684 ? 260.487 157.499 188.420 1.00 90.73  ? 687 ASP C C     1 
ATOM   8042 O O     . ASP B 2 684 ? 260.306 157.970 189.546 1.00 90.73  ? 687 ASP C O     1 
ATOM   8043 C CB    . ASP B 2 684 ? 259.083 155.427 188.384 1.00 90.73  ? 687 ASP C CB    1 
ATOM   8044 C CG    . ASP B 2 684 ? 258.995 153.957 188.031 1.00 90.73  ? 687 ASP C CG    1 
ATOM   8045 O OD1   . ASP B 2 684 ? 260.008 153.390 187.575 1.00 90.73  ? 687 ASP C OD1   1 
ATOM   8046 O OD2   . ASP B 2 684 ? 257.909 153.368 188.209 1.00 90.73  ? 687 ASP C OD2   1 
ATOM   8047 N N     . ASN B 2 685 ? 260.670 158.246 187.343 1.00 88.84  ? 688 ASN C N     1 
ATOM   8048 C CA    . ASN B 2 685 ? 260.842 159.691 187.422 1.00 88.84  ? 688 ASN C CA    1 
ATOM   8049 C C     . ASN B 2 685 ? 259.583 160.449 187.841 1.00 88.84  ? 688 ASN C C     1 
ATOM   8050 O O     . ASN B 2 685 ? 259.693 161.411 188.611 1.00 88.84  ? 688 ASN C O     1 
ATOM   8051 C CB    . ASN B 2 685 ? 261.352 160.220 186.084 1.00 88.84  ? 688 ASN C CB    1 
ATOM   8052 C CG    . ASN B 2 685 ? 262.670 159.600 185.685 1.00 88.84  ? 688 ASN C CG    1 
ATOM   8053 O OD1   . ASN B 2 685 ? 262.740 158.414 185.368 1.00 88.84  ? 688 ASN C OD1   1 
ATOM   8054 N ND2   . ASN B 2 685 ? 263.729 160.399 185.704 1.00 88.84  ? 688 ASN C ND2   1 
ATOM   8055 N N     . PRO B 2 686 ? 258.380 160.086 187.373 1.00 86.59  ? 689 PRO C N     1 
ATOM   8056 C CA    . PRO B 2 686 ? 257.193 160.800 187.873 1.00 86.59  ? 689 PRO C CA    1 
ATOM   8057 C C     . PRO B 2 686 ? 256.969 160.618 189.362 1.00 86.59  ? 689 PRO C C     1 
ATOM   8058 O O     . PRO B 2 686 ? 256.663 161.591 190.064 1.00 86.59  ? 689 PRO C O     1 
ATOM   8059 C CB    . PRO B 2 686 ? 256.049 160.201 187.043 1.00 86.59  ? 689 PRO C CB    1 
ATOM   8060 C CG    . PRO B 2 686 ? 256.570 158.906 186.551 1.00 86.59  ? 689 PRO C CG    1 
ATOM   8061 C CD    . PRO B 2 686 ? 258.017 159.146 186.299 1.00 86.59  ? 689 PRO C CD    1 
ATOM   8062 N N     . LEU B 2 687 ? 257.128 159.393 189.866 1.00 81.60  ? 690 LEU C N     1 
ATOM   8063 C CA    . LEU B 2 687 ? 256.977 159.140 191.296 1.00 81.60  ? 690 LEU C CA    1 
ATOM   8064 C C     . LEU B 2 687 ? 257.975 159.957 192.107 1.00 81.60  ? 690 LEU C C     1 
ATOM   8065 O O     . LEU B 2 687 ? 257.599 160.677 193.042 1.00 81.60  ? 690 LEU C O     1 
ATOM   8066 C CB    . LEU B 2 687 ? 257.153 157.648 191.575 1.00 81.60  ? 690 LEU C CB    1 
ATOM   8067 C CG    . LEU B 2 687 ? 256.795 157.130 192.966 1.00 81.60  ? 690 LEU C CG    1 
ATOM   8068 C CD1   . LEU B 2 687 ? 255.475 157.712 193.439 1.00 81.60  ? 690 LEU C CD1   1 
ATOM   8069 C CD2   . LEU B 2 687 ? 256.750 155.614 192.968 1.00 81.60  ? 690 LEU C CD2   1 
ATOM   8070 N N     . VAL B 2 688 ? 259.261 159.844 191.768 1.00 79.48  ? 691 VAL C N     1 
ATOM   8071 C CA    . VAL B 2 688 ? 260.297 160.527 192.531 1.00 79.48  ? 691 VAL C CA    1 
ATOM   8072 C C     . VAL B 2 688 ? 260.144 162.034 192.423 1.00 79.48  ? 691 VAL C C     1 
ATOM   8073 O O     . VAL B 2 688 ? 260.407 162.757 193.385 1.00 79.48  ? 691 VAL C O     1 
ATOM   8074 C CB    . VAL B 2 688 ? 261.691 160.061 192.071 1.00 79.48  ? 691 VAL C CB    1 
ATOM   8075 C CG1   . VAL B 2 688 ? 262.780 160.845 192.779 1.00 79.48  ? 691 VAL C CG1   1 
ATOM   8076 C CG2   . VAL B 2 688 ? 261.856 158.580 192.336 1.00 79.48  ? 691 VAL C CG2   1 
ATOM   8077 N N     . MET B 2 689 ? 259.687 162.536 191.275 1.00 81.72  ? 692 MET C N     1 
ATOM   8078 C CA    . MET B 2 689 ? 259.507 163.978 191.135 1.00 81.72  ? 692 MET C CA    1 
ATOM   8079 C C     . MET B 2 689 ? 258.324 164.474 191.959 1.00 81.72  ? 692 MET C C     1 
ATOM   8080 O O     . MET B 2 689 ? 258.394 165.545 192.573 1.00 81.72  ? 692 MET C O     1 
ATOM   8081 C CB    . MET B 2 689 ? 259.341 164.342 189.662 1.00 81.72  ? 692 MET C CB    1 
ATOM   8082 C CG    . MET B 2 689 ? 259.222 165.830 189.416 1.00 81.72  ? 692 MET C CG    1 
ATOM   8083 S SD    . MET B 2 689 ? 260.675 166.759 189.938 1.00 81.72  ? 692 MET C SD    1 
ATOM   8084 C CE    . MET B 2 689 ? 261.831 166.344 188.642 1.00 81.72  ? 692 MET C CE    1 
ATOM   8085 N N     . HIS B 2 690 ? 257.228 163.713 191.989 1.00 77.23  ? 693 HIS C N     1 
ATOM   8086 C CA    . HIS B 2 690 ? 256.121 164.053 192.877 1.00 77.23  ? 693 HIS C CA    1 
ATOM   8087 C C     . HIS B 2 690 ? 256.585 164.115 194.326 1.00 77.23  ? 693 HIS C C     1 
ATOM   8088 O O     . HIS B 2 690 ? 256.306 165.086 195.043 1.00 77.23  ? 693 HIS C O     1 
ATOM   8089 C CB    . HIS B 2 690 ? 254.997 163.032 192.713 1.00 77.23  ? 693 HIS C CB    1 
ATOM   8090 C CG    . HIS B 2 690 ? 253.848 163.242 193.646 1.00 77.23  ? 693 HIS C CG    1 
ATOM   8091 N ND1   . HIS B 2 690 ? 252.983 164.308 193.534 1.00 77.23  ? 693 HIS C ND1   1 
ATOM   8092 C CD2   . HIS B 2 690 ? 253.416 162.516 194.704 1.00 77.23  ? 693 HIS C CD2   1 
ATOM   8093 C CE1   . HIS B 2 690 ? 252.070 164.232 194.485 1.00 77.23  ? 693 HIS C CE1   1 
ATOM   8094 N NE2   . HIS B 2 690 ? 252.310 163.154 195.209 1.00 77.23  ? 693 HIS C NE2   1 
ATOM   8095 N N     . GLN B 2 691 ? 257.307 163.085 194.772 1.00 73.76  ? 694 GLN C N     1 
ATOM   8096 C CA    . GLN B 2 691 ? 257.802 163.068 196.146 1.00 73.76  ? 694 GLN C CA    1 
ATOM   8097 C C     . GLN B 2 691 ? 258.740 164.237 196.407 1.00 73.76  ? 694 GLN C C     1 
ATOM   8098 O O     . GLN B 2 691 ? 258.680 164.876 197.461 1.00 73.76  ? 694 GLN C O     1 
ATOM   8099 C CB    . GLN B 2 691 ? 258.509 161.746 196.435 1.00 73.76  ? 694 GLN C CB    1 
ATOM   8100 C CG    . GLN B 2 691 ? 257.663 160.530 196.173 1.00 73.76  ? 694 GLN C CG    1 
ATOM   8101 C CD    . GLN B 2 691 ? 258.288 159.270 196.711 1.00 73.76  ? 694 GLN C CD    1 
ATOM   8102 O OE1   . GLN B 2 691 ? 258.151 158.953 197.890 1.00 73.76  ? 694 GLN C OE1   1 
ATOM   8103 N NE2   . GLN B 2 691 ? 258.979 158.538 195.850 1.00 73.76  ? 694 GLN C NE2   1 
ATOM   8104 N N     . LEU B 2 692 ? 259.611 164.535 195.446 1.00 73.82  ? 695 LEU C N     1 
ATOM   8105 C CA    . LEU B 2 692 ? 260.600 165.587 195.597 1.00 73.82  ? 695 LEU C CA    1 
ATOM   8106 C C     . LEU B 2 692 ? 259.968 166.971 195.576 1.00 73.82  ? 695 LEU C C     1 
ATOM   8107 O O     . LEU B 2 692 ? 260.579 167.926 196.063 1.00 73.82  ? 695 LEU C O     1 
ATOM   8108 C CB    . LEU B 2 692 ? 261.635 165.442 194.482 1.00 73.82  ? 695 LEU C CB    1 
ATOM   8109 C CG    . LEU B 2 692 ? 262.941 166.223 194.491 1.00 73.82  ? 695 LEU C CG    1 
ATOM   8110 C CD1   . LEU B 2 692 ? 263.791 165.764 195.650 1.00 73.82  ? 695 LEU C CD1   1 
ATOM   8111 C CD2   . LEU B 2 692 ? 263.668 166.007 193.182 1.00 73.82  ? 695 LEU C CD2   1 
ATOM   8112 N N     . ARG B 2 693 ? 258.767 167.102 195.009 1.00 74.35  ? 696 ARG C N     1 
ATOM   8113 C CA    . ARG B 2 693 ? 258.028 168.356 195.130 1.00 74.35  ? 696 ARG C CA    1 
ATOM   8114 C C     . ARG B 2 693 ? 257.331 168.456 196.480 1.00 74.35  ? 696 ARG C C     1 
ATOM   8115 O O     . ARG B 2 693 ? 257.393 169.497 197.142 1.00 74.35  ? 696 ARG C O     1 
ATOM   8116 C CB    . ARG B 2 693 ? 257.003 168.495 194.005 1.00 74.35  ? 696 ARG C CB    1 
ATOM   8117 C CG    . ARG B 2 693 ? 257.564 169.038 192.712 1.00 74.35  ? 696 ARG C CG    1 
ATOM   8118 C CD    . ARG B 2 693 ? 256.457 169.498 191.787 1.00 74.35  ? 696 ARG C CD    1 
ATOM   8119 N NE    . ARG B 2 693 ? 256.861 169.455 190.388 1.00 74.35  ? 696 ARG C NE    1 
ATOM   8120 C CZ    . ARG B 2 693 ? 256.819 168.360 189.638 1.00 74.35  ? 696 ARG C CZ    1 
ATOM   8121 N NH1   . ARG B 2 693 ? 256.378 167.223 190.154 1.00 74.35  ? 696 ARG C NH1   1 
ATOM   8122 N NH2   . ARG B 2 693 ? 257.208 168.403 188.371 1.00 74.35  ? 696 ARG C NH2   1 
ATOM   8123 N N     . CYS B 2 694 ? 256.662 167.381 196.905 1.00 70.84  ? 697 CYS C N     1 
ATOM   8124 C CA    . CYS B 2 694 ? 255.947 167.422 198.177 1.00 70.84  ? 697 CYS C CA    1 
ATOM   8125 C C     . CYS B 2 694 ? 256.883 167.435 199.380 1.00 70.84  ? 697 CYS C C     1 
ATOM   8126 O O     . CYS B 2 694 ? 256.502 167.950 200.436 1.00 70.84  ? 697 CYS C O     1 
ATOM   8127 C CB    . CYS B 2 694 ? 254.985 166.241 198.279 1.00 70.84  ? 697 CYS C CB    1 
ATOM   8128 S SG    . CYS B 2 694 ? 253.875 166.069 196.868 1.00 70.84  ? 697 CYS C SG    1 
ATOM   8129 N N     . ASN B 2 695 ? 258.092 166.883 199.248 1.00 70.14  ? 698 ASN C N     1 
ATOM   8130 C CA    . ASN B 2 695 ? 259.004 166.799 200.385 1.00 70.14  ? 698 ASN C CA    1 
ATOM   8131 C C     . ASN B 2 695 ? 259.486 168.168 200.835 1.00 70.14  ? 698 ASN C C     1 
ATOM   8132 O O     . ASN B 2 695 ? 259.785 168.358 202.018 1.00 70.14  ? 698 ASN C O     1 
ATOM   8133 C CB    . ASN B 2 695 ? 260.204 165.925 200.034 1.00 70.14  ? 698 ASN C CB    1 
ATOM   8134 C CG    . ASN B 2 695 ? 259.993 164.478 200.398 1.00 70.14  ? 698 ASN C CG    1 
ATOM   8135 O OD1   . ASN B 2 695 ? 258.925 164.095 200.868 1.00 70.14  ? 698 ASN C OD1   1 
ATOM   8136 N ND2   . ASN B 2 695 ? 261.013 163.660 200.180 1.00 70.14  ? 698 ASN C ND2   1 
ATOM   8137 N N     . GLY B 2 696 ? 259.576 169.126 199.920 1.00 70.71  ? 699 GLY C N     1 
ATOM   8138 C CA    . GLY B 2 696 ? 260.144 170.419 200.221 1.00 70.71  ? 699 GLY C CA    1 
ATOM   8139 C C     . GLY B 2 696 ? 261.556 170.616 199.723 1.00 70.71  ? 699 GLY C C     1 
ATOM   8140 O O     . GLY B 2 696 ? 262.112 171.704 199.906 1.00 70.71  ? 699 GLY C O     1 
ATOM   8141 N N     . VAL B 2 697 ? 262.153 169.600 199.101 1.00 70.14  ? 700 VAL C N     1 
ATOM   8142 C CA    . VAL B 2 697 ? 263.517 169.725 198.601 1.00 70.14  ? 700 VAL C CA    1 
ATOM   8143 C C     . VAL B 2 697 ? 263.588 170.775 197.502 1.00 70.14  ? 700 VAL C C     1 
ATOM   8144 O O     . VAL B 2 697 ? 264.444 171.667 197.527 1.00 70.14  ? 700 VAL C O     1 
ATOM   8145 C CB    . VAL B 2 697 ? 264.030 168.362 198.108 1.00 70.14  ? 700 VAL C CB    1 
ATOM   8146 C CG1   . VAL B 2 697 ? 265.442 168.492 197.586 1.00 70.14  ? 700 VAL C CG1   1 
ATOM   8147 C CG2   . VAL B 2 697 ? 263.962 167.337 199.219 1.00 70.14  ? 700 VAL C CG2   1 
ATOM   8148 N N     . LEU B 2 698 ? 262.692 170.685 196.517 1.00 73.02  ? 701 LEU C N     1 
ATOM   8149 C CA    . LEU B 2 698 ? 262.714 171.646 195.422 1.00 73.02  ? 701 LEU C CA    1 
ATOM   8150 C C     . LEU B 2 698 ? 262.375 173.049 195.905 1.00 73.02  ? 701 LEU C C     1 
ATOM   8151 O O     . LEU B 2 698 ? 262.824 174.032 195.309 1.00 73.02  ? 701 LEU C O     1 
ATOM   8152 C CB    . LEU B 2 698 ? 261.758 171.205 194.316 1.00 73.02  ? 701 LEU C CB    1 
ATOM   8153 C CG    . LEU B 2 698 ? 262.179 169.899 193.642 1.00 73.02  ? 701 LEU C CG    1 
ATOM   8154 C CD1   . LEU B 2 698 ? 261.148 169.441 192.635 1.00 73.02  ? 701 LEU C CD1   1 
ATOM   8155 C CD2   . LEU B 2 698 ? 263.532 170.060 192.981 1.00 73.02  ? 701 LEU C CD2   1 
ATOM   8156 N N     . GLU B 2 699 ? 261.619 173.166 196.996 1.00 74.15  ? 702 GLU C N     1 
ATOM   8157 C CA    . GLU B 2 699 ? 261.376 174.479 197.584 1.00 74.15  ? 702 GLU C CA    1 
ATOM   8158 C C     . GLU B 2 699 ? 262.663 175.066 198.153 1.00 74.15  ? 702 GLU C C     1 
ATOM   8159 O O     . GLU B 2 699 ? 262.986 176.236 197.913 1.00 74.15  ? 702 GLU C O     1 
ATOM   8160 C CB    . GLU B 2 699 ? 260.302 174.376 198.664 1.00 74.15  ? 702 GLU C CB    1 
ATOM   8161 C CG    . GLU B 2 699 ? 260.293 175.536 199.635 1.00 74.15  ? 702 GLU C CG    1 
ATOM   8162 C CD    . GLU B 2 699 ? 259.516 176.723 199.118 1.00 74.15  ? 702 GLU C CD    1 
ATOM   8163 O OE1   . GLU B 2 699 ? 258.650 176.528 198.243 1.00 74.15  ? 702 GLU C OE1   1 
ATOM   8164 O OE2   . GLU B 2 699 ? 259.770 177.853 199.582 1.00 74.15  ? 702 GLU C OE2   1 
ATOM   8165 N N     . GLY B 2 700 ? 263.419 174.264 198.904 1.00 74.27  ? 703 GLY C N     1 
ATOM   8166 C CA    . GLY B 2 700 ? 264.708 174.723 199.388 1.00 74.27  ? 703 GLY C CA    1 
ATOM   8167 C C     . GLY B 2 700 ? 265.669 175.059 198.267 1.00 74.27  ? 703 GLY C C     1 
ATOM   8168 O O     . GLY B 2 700 ? 266.482 175.977 198.393 1.00 74.27  ? 703 GLY C O     1 
ATOM   8169 N N     . ILE B 2 701 ? 265.585 174.332 197.154 1.00 76.18  ? 704 ILE C N     1 
ATOM   8170 C CA    . ILE B 2 701 ? 266.444 174.629 196.013 1.00 76.18  ? 704 ILE C CA    1 
ATOM   8171 C C     . ILE B 2 701 ? 266.040 175.948 195.366 1.00 76.18  ? 704 ILE C C     1 
ATOM   8172 O O     . ILE B 2 701 ? 266.896 176.761 195.000 1.00 76.18  ? 704 ILE C O     1 
ATOM   8173 C CB    . ILE B 2 701 ? 266.410 173.461 195.016 1.00 76.18  ? 704 ILE C CB    1 
ATOM   8174 C CG1   . ILE B 2 701 ? 267.005 172.220 195.675 1.00 76.18  ? 704 ILE C CG1   1 
ATOM   8175 C CG2   . ILE B 2 701 ? 267.172 173.811 193.758 1.00 76.18  ? 704 ILE C CG2   1 
ATOM   8176 C CD1   . ILE B 2 701 ? 266.721 170.950 194.945 1.00 76.18  ? 704 ILE C CD1   1 
ATOM   8177 N N     . ARG B 2 702 ? 264.736 176.182 195.213 1.00 77.63  ? 705 ARG C N     1 
ATOM   8178 C CA    . ARG B 2 702 ? 264.267 177.482 194.746 1.00 77.63  ? 705 ARG C CA    1 
ATOM   8179 C C     . ARG B 2 702 ? 264.730 178.600 195.664 1.00 77.63  ? 705 ARG C C     1 
ATOM   8180 O O     . ARG B 2 702 ? 265.008 179.711 195.202 1.00 77.63  ? 705 ARG C O     1 
ATOM   8181 C CB    . ARG B 2 702 ? 262.743 177.484 194.644 1.00 77.63  ? 705 ARG C CB    1 
ATOM   8182 C CG    . ARG B 2 702 ? 262.152 178.811 194.201 1.00 77.63  ? 705 ARG C CG    1 
ATOM   8183 C CD    . ARG B 2 702 ? 260.642 178.833 194.362 1.00 77.63  ? 705 ARG C CD    1 
ATOM   8184 N NE    . ARG B 2 702 ? 260.236 178.729 195.760 1.00 77.63  ? 705 ARG C NE    1 
ATOM   8185 C CZ    . ARG B 2 702 ? 260.184 179.756 196.602 1.00 77.63  ? 705 ARG C CZ    1 
ATOM   8186 N NH1   . ARG B 2 702 ? 260.514 180.972 196.191 1.00 77.63  ? 705 ARG C NH1   1 
ATOM   8187 N NH2   . ARG B 2 702 ? 259.803 179.566 197.856 1.00 77.63  ? 705 ARG C NH2   1 
ATOM   8188 N N     . ILE B 2 703 ? 264.817 178.327 196.965 1.00 78.15  ? 706 ILE C N     1 
ATOM   8189 C CA    . ILE B 2 703 ? 265.288 179.338 197.905 1.00 78.15  ? 706 ILE C CA    1 
ATOM   8190 C C     . ILE B 2 703 ? 266.771 179.611 197.697 1.00 78.15  ? 706 ILE C C     1 
ATOM   8191 O O     . ILE B 2 703 ? 267.201 180.766 197.609 1.00 78.15  ? 706 ILE C O     1 
ATOM   8192 C CB    . ILE B 2 703 ? 264.999 178.902 199.352 1.00 78.15  ? 706 ILE C CB    1 
ATOM   8193 C CG1   . ILE B 2 703 ? 263.497 178.881 199.617 1.00 78.15  ? 706 ILE C CG1   1 
ATOM   8194 C CG2   . ILE B 2 703 ? 265.685 179.827 200.318 1.00 78.15  ? 706 ILE C CG2   1 
ATOM   8195 C CD1   . ILE B 2 703 ? 262.800 180.143 199.205 1.00 78.15  ? 706 ILE C CD1   1 
ATOM   8196 N N     . CYS B 2 704 ? 267.578 178.553 197.620 1.00 80.99  ? 707 CYS C N     1 
ATOM   8197 C CA    . CYS B 2 704 ? 269.019 178.726 197.478 1.00 80.99  ? 707 CYS C CA    1 
ATOM   8198 C C     . CYS B 2 704 ? 269.404 179.272 196.112 1.00 80.99  ? 707 CYS C C     1 
ATOM   8199 O O     . CYS B 2 704 ? 270.510 179.799 195.959 1.00 80.99  ? 707 CYS C O     1 
ATOM   8200 C CB    . CYS B 2 704 ? 269.743 177.403 197.730 1.00 80.99  ? 707 CYS C CB    1 
ATOM   8201 S SG    . CYS B 2 704 ? 269.770 176.281 196.321 1.00 80.99  ? 707 CYS C SG    1 
ATOM   8202 N N     . ARG B 2 705 ? 268.519 179.166 195.124 1.00 82.28  ? 708 ARG C N     1 
ATOM   8203 C CA    . ARG B 2 705 ? 268.759 179.672 193.781 1.00 82.28  ? 708 ARG C CA    1 
ATOM   8204 C C     . ARG B 2 705 ? 268.563 181.182 193.678 1.00 82.28  ? 708 ARG C C     1 
ATOM   8205 O O     . ARG B 2 705 ? 268.713 181.753 192.593 1.00 82.28  ? 708 ARG C O     1 
ATOM   8206 C CB    . ARG B 2 705 ? 267.843 178.943 192.794 1.00 82.28  ? 708 ARG C CB    1 
ATOM   8207 C CG    . ARG B 2 705 ? 268.211 179.068 191.332 1.00 82.28  ? 708 ARG C CG    1 
ATOM   8208 C CD    . ARG B 2 705 ? 267.205 178.329 190.480 1.00 82.28  ? 708 ARG C CD    1 
ATOM   8209 N NE    . ARG B 2 705 ? 265.845 178.773 190.760 1.00 82.28  ? 708 ARG C NE    1 
ATOM   8210 C CZ    . ARG B 2 705 ? 264.791 177.965 190.809 1.00 82.28  ? 708 ARG C CZ    1 
ATOM   8211 N NH1   . ARG B 2 705 ? 264.942 176.665 190.601 1.00 82.28  ? 708 ARG C NH1   1 
ATOM   8212 N NH2   . ARG B 2 705 ? 263.589 178.456 191.071 1.00 82.28  ? 708 ARG C NH2   1 
ATOM   8213 N N     . LYS B 2 706 ? 268.253 181.849 194.790 1.00 82.89  ? 709 LYS C N     1 
ATOM   8214 C CA    . LYS B 2 706 ? 268.062 183.291 194.803 1.00 82.89  ? 709 LYS C CA    1 
ATOM   8215 C C     . LYS B 2 706 ? 269.244 184.059 195.367 1.00 82.89  ? 709 LYS C C     1 
ATOM   8216 O O     . LYS B 2 706 ? 269.440 185.217 194.985 1.00 82.89  ? 709 LYS C O     1 
ATOM   8217 C CB    . LYS B 2 706 ? 266.808 183.659 195.609 1.00 82.89  ? 709 LYS C CB    1 
ATOM   8218 C CG    . LYS B 2 706 ? 265.505 183.466 194.851 1.00 82.89  ? 709 LYS C CG    1 
ATOM   8219 C CD    . LYS B 2 706 ? 264.309 183.421 195.791 1.00 82.89  ? 709 LYS C CD    1 
ATOM   8220 C CE    . LYS B 2 706 ? 264.491 184.349 196.979 1.00 82.89  ? 709 LYS C CE    1 
ATOM   8221 N NZ    . LYS B 2 706 ? 263.341 184.268 197.916 1.00 82.89  ? 709 LYS C NZ    1 
ATOM   8222 N N     . GLY B 2 707 ? 270.030 183.460 196.254 1.00 88.30  ? 710 GLY C N     1 
ATOM   8223 C CA    . GLY B 2 707 ? 271.233 184.096 196.746 1.00 88.30  ? 710 GLY C CA    1 
ATOM   8224 C C     . GLY B 2 707 ? 272.446 183.725 195.919 1.00 88.30  ? 710 GLY C C     1 
ATOM   8225 O O     . GLY B 2 707 ? 272.425 183.848 194.692 1.00 88.30  ? 710 GLY C O     1 
ATOM   8226 N N     . PHE B 2 708 ? 273.511 183.269 196.579 1.00 91.59  ? 711 PHE C N     1 
ATOM   8227 C CA    . PHE B 2 708 ? 274.745 182.848 195.918 1.00 91.59  ? 711 PHE C CA    1 
ATOM   8228 C C     . PHE B 2 708 ? 275.018 181.401 196.304 1.00 91.59  ? 711 PHE C C     1 
ATOM   8229 O O     . PHE B 2 708 ? 275.745 181.134 197.273 1.00 91.59  ? 711 PHE C O     1 
ATOM   8230 C CB    . PHE B 2 708 ? 275.919 183.746 196.301 1.00 91.59  ? 711 PHE C CB    1 
ATOM   8231 C CG    . PHE B 2 708 ? 275.773 185.173 195.852 1.00 91.59  ? 711 PHE C CG    1 
ATOM   8232 C CD1   . PHE B 2 708 ? 276.604 185.688 194.878 1.00 91.59  ? 711 PHE C CD1   1 
ATOM   8233 C CD2   . PHE B 2 708 ? 274.824 186.006 196.420 1.00 91.59  ? 711 PHE C CD2   1 
ATOM   8234 C CE1   . PHE B 2 708 ? 276.480 186.998 194.464 1.00 91.59  ? 711 PHE C CE1   1 
ATOM   8235 C CE2   . PHE B 2 708 ? 274.696 187.314 196.008 1.00 91.59  ? 711 PHE C CE2   1 
ATOM   8236 C CZ    . PHE B 2 708 ? 275.525 187.810 195.031 1.00 91.59  ? 711 PHE C CZ    1 
ATOM   8237 N N     . PRO B 2 709 ? 274.455 180.435 195.583 1.00 89.97  ? 712 PRO C N     1 
ATOM   8238 C CA    . PRO B 2 709 ? 274.650 179.027 195.953 1.00 89.97  ? 712 PRO C CA    1 
ATOM   8239 C C     . PRO B 2 709 ? 276.077 178.539 195.761 1.00 89.97  ? 712 PRO C C     1 
ATOM   8240 O O     . PRO B 2 709 ? 276.624 177.858 196.631 1.00 89.97  ? 712 PRO C O     1 
ATOM   8241 C CB    . PRO B 2 709 ? 273.682 178.285 195.024 1.00 89.97  ? 712 PRO C CB    1 
ATOM   8242 C CG    . PRO B 2 709 ? 273.467 179.211 193.882 1.00 89.97  ? 712 PRO C CG    1 
ATOM   8243 C CD    . PRO B 2 709 ? 273.513 180.586 194.464 1.00 89.97  ? 712 PRO C CD    1 
ATOM   8244 N N     . ASN B 2 710 ? 276.685 178.874 194.626 1.00 91.99  ? 713 ASN C N     1 
ATOM   8245 C CA    . ASN B 2 710 ? 278.015 178.379 194.286 1.00 91.99  ? 713 ASN C CA    1 
ATOM   8246 C C     . ASN B 2 710 ? 279.061 179.151 195.079 1.00 91.99  ? 713 ASN C C     1 
ATOM   8247 O O     . ASN B 2 710 ? 279.406 180.283 194.728 1.00 91.99  ? 713 ASN C O     1 
ATOM   8248 C CB    . ASN B 2 710 ? 278.259 178.505 192.787 1.00 91.99  ? 713 ASN C CB    1 
ATOM   8249 C CG    . ASN B 2 710 ? 277.700 177.336 192.010 1.00 91.99  ? 713 ASN C CG    1 
ATOM   8250 O OD1   . ASN B 2 710 ? 277.770 176.194 192.457 1.00 91.99  ? 713 ASN C OD1   1 
ATOM   8251 N ND2   . ASN B 2 710 ? 277.139 177.613 190.841 1.00 91.99  ? 713 ASN C ND2   1 
ATOM   8252 N N     . ARG B 2 711 ? 279.578 178.533 196.138 1.00 92.69  ? 714 ARG C N     1 
ATOM   8253 C CA    . ARG B 2 711 ? 280.542 179.158 197.039 1.00 92.69  ? 714 ARG C CA    1 
ATOM   8254 C C     . ARG B 2 711 ? 281.829 178.347 196.999 1.00 92.69  ? 714 ARG C C     1 
ATOM   8255 O O     . ARG B 2 711 ? 281.852 177.189 197.429 1.00 92.69  ? 714 ARG C O     1 
ATOM   8256 C CB    . ARG B 2 711 ? 279.975 179.240 198.455 1.00 92.69  ? 714 ARG C CB    1 
ATOM   8257 C CG    . ARG B 2 711 ? 278.522 179.666 198.470 1.00 92.69  ? 714 ARG C CG    1 
ATOM   8258 C CD    . ARG B 2 711 ? 277.841 179.417 199.798 1.00 92.69  ? 714 ARG C CD    1 
ATOM   8259 N NE    . ARG B 2 711 ? 276.512 180.022 199.812 1.00 92.69  ? 714 ARG C NE    1 
ATOM   8260 C CZ    . ARG B 2 711 ? 275.695 180.017 200.858 1.00 92.69  ? 714 ARG C CZ    1 
ATOM   8261 N NH1   . ARG B 2 711 ? 276.063 179.434 201.989 1.00 92.69  ? 714 ARG C NH1   1 
ATOM   8262 N NH2   . ARG B 2 711 ? 274.507 180.596 200.771 1.00 92.69  ? 714 ARG C NH2   1 
ATOM   8263 N N     . ILE B 2 712 ? 282.894 178.952 196.480 1.00 100.41 ? 715 ILE C N     1 
ATOM   8264 C CA    . ILE B 2 712 ? 284.162 178.269 196.265 1.00 100.41 ? 715 ILE C CA    1 
ATOM   8265 C C     . ILE B 2 712 ? 285.248 178.980 197.060 1.00 100.41 ? 715 ILE C C     1 
ATOM   8266 O O     . ILE B 2 712 ? 285.249 180.208 197.186 1.00 100.41 ? 715 ILE C O     1 
ATOM   8267 C CB    . ILE B 2 712 ? 284.527 178.221 194.764 1.00 100.41 ? 715 ILE C CB    1 
ATOM   8268 C CG1   . ILE B 2 712 ? 283.409 177.560 193.960 1.00 100.41 ? 715 ILE C CG1   1 
ATOM   8269 C CG2   . ILE B 2 712 ? 285.818 177.460 194.542 1.00 100.41 ? 715 ILE C CG2   1 
ATOM   8270 C CD1   . ILE B 2 712 ? 283.149 176.127 194.344 1.00 100.41 ? 715 ILE C CD1   1 
ATOM   8271 N N     . LEU B 2 713 ? 286.179 178.195 197.599 1.00 106.18 ? 716 LEU C N     1 
ATOM   8272 C CA    . LEU B 2 713 ? 287.353 178.748 198.255 1.00 106.18 ? 716 LEU C CA    1 
ATOM   8273 C C     . LEU B 2 713 ? 288.229 179.474 197.235 1.00 106.18 ? 716 LEU C C     1 
ATOM   8274 O O     . LEU B 2 713 ? 287.997 179.429 196.024 1.00 106.18 ? 716 LEU C O     1 
ATOM   8275 C CB    . LEU B 2 713 ? 288.138 177.642 198.956 1.00 106.18 ? 716 LEU C CB    1 
ATOM   8276 C CG    . LEU B 2 713 ? 287.485 176.984 200.169 1.00 106.18 ? 716 LEU C CG    1 
ATOM   8277 C CD1   . LEU B 2 713 ? 288.280 175.772 200.606 1.00 106.18 ? 716 LEU C CD1   1 
ATOM   8278 C CD2   . LEU B 2 713 ? 287.386 177.983 201.304 1.00 106.18 ? 716 LEU C CD2   1 
ATOM   8279 N N     . TYR B 2 714 ? 289.261 180.154 197.732 1.00 108.30 ? 717 TYR C N     1 
ATOM   8280 C CA    . TYR B 2 714 ? 290.143 180.881 196.830 1.00 108.30 ? 717 TYR C CA    1 
ATOM   8281 C C     . TYR B 2 714 ? 291.235 179.992 196.259 1.00 108.30 ? 717 TYR C C     1 
ATOM   8282 O O     . TYR B 2 714 ? 291.662 180.203 195.121 1.00 108.30 ? 717 TYR C O     1 
ATOM   8283 C CB    . TYR B 2 714 ? 290.766 182.078 197.544 1.00 108.30 ? 717 TYR C CB    1 
ATOM   8284 C CG    . TYR B 2 714 ? 289.821 183.239 197.709 1.00 108.30 ? 717 TYR C CG    1 
ATOM   8285 C CD1   . TYR B 2 714 ? 288.701 183.361 196.906 1.00 108.30 ? 717 TYR C CD1   1 
ATOM   8286 C CD2   . TYR B 2 714 ? 290.053 184.219 198.661 1.00 108.30 ? 717 TYR C CD2   1 
ATOM   8287 C CE1   . TYR B 2 714 ? 287.836 184.420 197.051 1.00 108.30 ? 717 TYR C CE1   1 
ATOM   8288 C CE2   . TYR B 2 714 ? 289.191 185.282 198.814 1.00 108.30 ? 717 TYR C CE2   1 
ATOM   8289 C CZ    . TYR B 2 714 ? 288.084 185.376 198.005 1.00 108.30 ? 717 TYR C CZ    1 
ATOM   8290 O OH    . TYR B 2 714 ? 287.221 186.435 198.149 1.00 108.30 ? 717 TYR C OH    1 
ATOM   8291 N N     . GLY B 2 715 ? 291.688 178.993 197.014 1.00 112.83 ? 718 GLY C N     1 
ATOM   8292 C CA    . GLY B 2 715 ? 292.722 178.111 196.499 1.00 112.83 ? 718 GLY C CA    1 
ATOM   8293 C C     . GLY B 2 715 ? 292.235 177.261 195.341 1.00 112.83 ? 718 GLY C C     1 
ATOM   8294 O O     . GLY B 2 715 ? 292.888 177.177 194.298 1.00 112.83 ? 718 GLY C O     1 
ATOM   8295 N N     . ASP B 2 716 ? 291.069 176.634 195.503 1.00 113.11 ? 719 ASP C N     1 
ATOM   8296 C CA    . ASP B 2 716 ? 290.574 175.711 194.487 1.00 113.11 ? 719 ASP C CA    1 
ATOM   8297 C C     . ASP B 2 716 ? 290.232 176.440 193.193 1.00 113.11 ? 719 ASP C C     1 
ATOM   8298 O O     . ASP B 2 716 ? 290.492 175.929 192.098 1.00 113.11 ? 719 ASP C O     1 
ATOM   8299 C CB    . ASP B 2 716 ? 289.354 174.964 195.020 1.00 113.11 ? 719 ASP C CB    1 
ATOM   8300 C CG    . ASP B 2 716 ? 289.687 174.082 196.206 1.00 113.11 ? 719 ASP C CG    1 
ATOM   8301 O OD1   . ASP B 2 716 ? 290.836 173.601 196.289 1.00 113.11 ? 719 ASP C OD1   1 
ATOM   8302 O OD2   . ASP B 2 716 ? 288.800 173.879 197.060 1.00 113.11 ? 719 ASP C OD2   1 
ATOM   8303 N N     . PHE B 2 717 ? 289.656 177.637 193.299 1.00 113.35 ? 720 PHE C N     1 
ATOM   8304 C CA    . PHE B 2 717 ? 289.338 178.410 192.104 1.00 113.35 ? 720 PHE C CA    1 
ATOM   8305 C C     . PHE B 2 717 ? 290.594 179.019 191.495 1.00 113.35 ? 720 PHE C C     1 
ATOM   8306 O O     . PHE B 2 717 ? 290.740 179.058 190.268 1.00 113.35 ? 720 PHE C O     1 
ATOM   8307 C CB    . PHE B 2 717 ? 288.317 179.495 192.440 1.00 113.35 ? 720 PHE C CB    1 
ATOM   8308 C CG    . PHE B 2 717 ? 288.297 180.628 191.460 1.00 113.35 ? 720 PHE C CG    1 
ATOM   8309 C CD1   . PHE B 2 717 ? 287.625 180.505 190.258 1.00 113.35 ? 720 PHE C CD1   1 
ATOM   8310 C CD2   . PHE B 2 717 ? 288.945 181.817 191.741 1.00 113.35 ? 720 PHE C CD2   1 
ATOM   8311 C CE1   . PHE B 2 717 ? 287.603 181.544 189.353 1.00 113.35 ? 720 PHE C CE1   1 
ATOM   8312 C CE2   . PHE B 2 717 ? 288.926 182.858 190.839 1.00 113.35 ? 720 PHE C CE2   1 
ATOM   8313 C CZ    . PHE B 2 717 ? 288.252 182.722 189.644 1.00 113.35 ? 720 PHE C CZ    1 
ATOM   8314 N N     . ARG B 2 718 ? 291.506 179.510 192.337 1.00 113.96 ? 721 ARG C N     1 
ATOM   8315 C CA    . ARG B 2 718 ? 292.781 180.026 191.853 1.00 113.96 ? 721 ARG C CA    1 
ATOM   8316 C C     . ARG B 2 718 ? 293.574 178.948 191.128 1.00 113.96 ? 721 ARG C C     1 
ATOM   8317 O O     . ARG B 2 718 ? 294.377 179.256 190.241 1.00 113.96 ? 721 ARG C O     1 
ATOM   8318 C CB    . ARG B 2 718 ? 293.575 180.592 193.034 1.00 113.96 ? 721 ARG C CB    1 
ATOM   8319 C CG    . ARG B 2 718 ? 295.041 180.879 192.771 1.00 113.96 ? 721 ARG C CG    1 
ATOM   8320 C CD    . ARG B 2 718 ? 295.684 181.551 193.976 1.00 113.96 ? 721 ARG C CD    1 
ATOM   8321 N NE    . ARG B 2 718 ? 295.033 182.816 194.307 1.00 113.96 ? 721 ARG C NE    1 
ATOM   8322 C CZ    . ARG B 2 718 ? 294.745 183.212 195.543 1.00 113.96 ? 721 ARG C CZ    1 
ATOM   8323 N NH1   . ARG B 2 718 ? 295.054 182.445 196.579 1.00 113.96 ? 721 ARG C NH1   1 
ATOM   8324 N NH2   . ARG B 2 718 ? 294.150 184.379 195.744 1.00 113.96 ? 721 ARG C NH2   1 
ATOM   8325 N N     . GLN B 2 719 ? 293.350 177.682 191.478 1.00 113.52 ? 722 GLN C N     1 
ATOM   8326 C CA    . GLN B 2 719 ? 294.057 176.588 190.824 1.00 113.52 ? 722 GLN C CA    1 
ATOM   8327 C C     . GLN B 2 719 ? 293.344 176.142 189.552 1.00 113.52 ? 722 GLN C C     1 
ATOM   8328 O O     . GLN B 2 719 ? 293.922 176.178 188.461 1.00 113.52 ? 722 GLN C O     1 
ATOM   8329 C CB    . GLN B 2 719 ? 294.208 175.415 191.796 1.00 113.52 ? 722 GLN C CB    1 
ATOM   8330 C CG    . GLN B 2 719 ? 295.079 174.284 191.284 1.00 113.52 ? 722 GLN C CG    1 
ATOM   8331 C CD    . GLN B 2 719 ? 294.302 173.284 190.454 1.00 113.52 ? 722 GLN C CD    1 
ATOM   8332 O OE1   . GLN B 2 719 ? 293.105 173.090 190.658 1.00 113.52 ? 722 GLN C OE1   1 
ATOM   8333 N NE2   . GLN B 2 719 ? 294.979 172.647 189.507 1.00 113.52 ? 722 GLN C NE2   1 
ATOM   8334 N N     . ARG B 2 720 ? 292.084 175.718 189.672 1.00 110.37 ? 723 ARG C N     1 
ATOM   8335 C CA    . ARG B 2 720 ? 291.406 175.109 188.532 1.00 110.37 ? 723 ARG C CA    1 
ATOM   8336 C C     . ARG B 2 720 ? 291.119 176.114 187.423 1.00 110.37 ? 723 ARG C C     1 
ATOM   8337 O O     . ARG B 2 720 ? 291.092 175.738 186.247 1.00 110.37 ? 723 ARG C O     1 
ATOM   8338 C CB    . ARG B 2 720 ? 290.108 174.440 188.983 1.00 110.37 ? 723 ARG C CB    1 
ATOM   8339 C CG    . ARG B 2 720 ? 289.529 173.480 187.953 1.00 110.37 ? 723 ARG C CG    1 
ATOM   8340 C CD    . ARG B 2 720 ? 288.158 172.973 188.360 1.00 110.37 ? 723 ARG C CD    1 
ATOM   8341 N NE    . ARG B 2 720 ? 287.714 171.874 187.508 1.00 110.37 ? 723 ARG C NE    1 
ATOM   8342 C CZ    . ARG B 2 720 ? 288.021 170.598 187.717 1.00 110.37 ? 723 ARG C CZ    1 
ATOM   8343 N NH1   . ARG B 2 720 ? 288.777 170.259 188.751 1.00 110.37 ? 723 ARG C NH1   1 
ATOM   8344 N NH2   . ARG B 2 720 ? 287.574 169.661 186.893 1.00 110.37 ? 723 ARG C NH2   1 
ATOM   8345 N N     . TYR B 2 721 ? 290.910 177.382 187.763 1.00 109.45 ? 724 TYR C N     1 
ATOM   8346 C CA    . TYR B 2 721 ? 290.564 178.405 186.784 1.00 109.45 ? 724 TYR C CA    1 
ATOM   8347 C C     . TYR B 2 721 ? 291.662 179.453 186.664 1.00 109.45 ? 724 TYR C C     1 
ATOM   8348 O O     . TYR B 2 721 ? 291.403 180.625 186.391 1.00 109.45 ? 724 TYR C O     1 
ATOM   8349 C CB    . TYR B 2 721 ? 289.223 179.052 187.124 1.00 109.45 ? 724 TYR C CB    1 
ATOM   8350 C CG    . TYR B 2 721 ? 288.073 178.077 187.048 1.00 109.45 ? 724 TYR C CG    1 
ATOM   8351 C CD1   . TYR B 2 721 ? 287.707 177.508 185.838 1.00 109.45 ? 724 TYR C CD1   1 
ATOM   8352 C CD2   . TYR B 2 721 ? 287.370 177.707 188.183 1.00 109.45 ? 724 TYR C CD2   1 
ATOM   8353 C CE1   . TYR B 2 721 ? 286.668 176.607 185.758 1.00 109.45 ? 724 TYR C CE1   1 
ATOM   8354 C CE2   . TYR B 2 721 ? 286.327 176.805 188.113 1.00 109.45 ? 724 TYR C CE2   1 
ATOM   8355 C CZ    . TYR B 2 721 ? 285.982 176.259 186.897 1.00 109.45 ? 724 TYR C CZ    1 
ATOM   8356 O OH    . TYR B 2 721 ? 284.944 175.359 186.813 1.00 109.45 ? 724 TYR C OH    1 
ATOM   8357 N N     . ARG B 2 722 ? 292.909 179.032 186.860 1.00 112.90 ? 725 ARG C N     1 
ATOM   8358 C CA    . ARG B 2 722 ? 294.062 179.876 186.576 1.00 112.90 ? 725 ARG C CA    1 
ATOM   8359 C C     . ARG B 2 722 ? 294.322 180.025 185.085 1.00 112.90 ? 725 ARG C C     1 
ATOM   8360 O O     . ARG B 2 722 ? 295.160 180.845 184.697 1.00 112.90 ? 725 ARG C O     1 
ATOM   8361 C CB    . ARG B 2 722 ? 295.314 179.303 187.244 1.00 112.90 ? 725 ARG C CB    1 
ATOM   8362 C CG    . ARG B 2 722 ? 295.814 178.027 186.586 1.00 112.90 ? 725 ARG C CG    1 
ATOM   8363 C CD    . ARG B 2 722 ? 297.092 177.510 187.230 1.00 112.90 ? 725 ARG C CD    1 
ATOM   8364 N NE    . ARG B 2 722 ? 297.573 176.299 186.568 1.00 112.90 ? 725 ARG C NE    1 
ATOM   8365 C CZ    . ARG B 2 722 ? 298.647 175.612 186.945 1.00 112.90 ? 725 ARG C CZ    1 
ATOM   8366 N NH1   . ARG B 2 722 ? 299.361 176.014 187.987 1.00 112.90 ? 725 ARG C NH1   1 
ATOM   8367 N NH2   . ARG B 2 722 ? 299.007 174.522 186.280 1.00 112.90 ? 725 ARG C NH2   1 
ATOM   8368 N N     . ILE B 2 723 ? 293.616 179.263 184.252 1.00 112.39 ? 726 ILE C N     1 
ATOM   8369 C CA    . ILE B 2 723 ? 293.928 179.139 182.831 1.00 112.39 ? 726 ILE C CA    1 
ATOM   8370 C C     . ILE B 2 723 ? 293.641 180.471 182.146 1.00 112.39 ? 726 ILE C C     1 
ATOM   8371 O O     . ILE B 2 723 ? 292.484 180.872 181.997 1.00 112.39 ? 726 ILE C O     1 
ATOM   8372 C CB    . ILE B 2 723 ? 293.136 177.999 182.186 1.00 112.39 ? 726 ILE C CB    1 
ATOM   8373 C CG1   . ILE B 2 723 ? 293.504 176.671 182.848 1.00 112.39 ? 726 ILE C CG1   1 
ATOM   8374 C CG2   . ILE B 2 723 ? 293.407 177.943 180.696 1.00 112.39 ? 726 ILE C CG2   1 
ATOM   8375 C CD1   . ILE B 2 723 ? 293.013 175.458 182.101 1.00 112.39 ? 726 ILE C CD1   1 
ATOM   8376 N N     . LEU B 2 724 ? 294.700 181.158 181.729 1.00 114.04 ? 727 LEU C N     1 
ATOM   8377 C CA    . LEU B 2 724 ? 294.573 182.416 181.008 1.00 114.04 ? 727 LEU C CA    1 
ATOM   8378 C C     . LEU B 2 724 ? 295.111 182.271 179.589 1.00 114.04 ? 727 LEU C C     1 
ATOM   8379 O O     . LEU B 2 724 ? 296.220 181.775 179.385 1.00 114.04 ? 727 LEU C O     1 
ATOM   8380 C CB    . LEU B 2 724 ? 295.312 183.536 181.742 1.00 114.04 ? 727 LEU C CB    1 
ATOM   8381 C CG    . LEU B 2 724 ? 294.847 183.851 183.164 1.00 114.04 ? 727 LEU C CG    1 
ATOM   8382 C CD1   . LEU B 2 724 ? 295.381 185.202 183.609 1.00 114.04 ? 727 LEU C CD1   1 
ATOM   8383 C CD2   . LEU B 2 724 ? 293.332 183.820 183.245 1.00 114.04 ? 727 LEU C CD2   1 
ATOM   8384 N N     . GLY B 2 740 ? 294.607 188.455 194.145 1.00 116.78 ? 743 GLY C N     1 
ATOM   8385 C CA    . GLY B 2 740 ? 294.817 187.190 193.464 1.00 116.78 ? 743 GLY C CA    1 
ATOM   8386 C C     . GLY B 2 740 ? 293.658 186.803 192.569 1.00 116.78 ? 743 GLY C C     1 
ATOM   8387 O O     . GLY B 2 740 ? 293.667 187.080 191.370 1.00 116.78 ? 743 GLY C O     1 
ATOM   8388 N N     . ALA B 2 741 ? 292.653 186.154 193.159 1.00 117.49 ? 744 ALA C N     1 
ATOM   8389 C CA    . ALA B 2 741 ? 291.448 185.810 192.416 1.00 117.49 ? 744 ALA C CA    1 
ATOM   8390 C C     . ALA B 2 741 ? 290.708 187.043 191.919 1.00 117.49 ? 744 ALA C C     1 
ATOM   8391 O O     . ALA B 2 741 ? 290.104 186.997 190.841 1.00 117.49 ? 744 ALA C O     1 
ATOM   8392 C CB    . ALA B 2 741 ? 290.522 184.958 193.283 1.00 117.49 ? 744 ALA C CB    1 
ATOM   8393 N N     . GLU B 2 742 ? 290.739 188.138 192.683 1.00 117.58 ? 745 GLU C N     1 
ATOM   8394 C CA    . GLU B 2 742 ? 290.128 189.382 192.228 1.00 117.58 ? 745 GLU C CA    1 
ATOM   8395 C C     . GLU B 2 742 ? 290.703 189.805 190.882 1.00 117.58 ? 745 GLU C C     1 
ATOM   8396 O O     . GLU B 2 742 ? 289.961 190.163 189.960 1.00 117.58 ? 745 GLU C O     1 
ATOM   8397 C CB    . GLU B 2 742 ? 290.334 190.485 193.271 1.00 117.58 ? 745 GLU C CB    1 
ATOM   8398 C CG    . GLU B 2 742 ? 289.682 190.224 194.625 1.00 117.58 ? 745 GLU C CG    1 
ATOM   8399 C CD    . GLU B 2 742 ? 290.589 189.459 195.577 1.00 117.58 ? 745 GLU C CD    1 
ATOM   8400 O OE1   . GLU B 2 742 ? 291.759 189.215 195.217 1.00 117.58 ? 745 GLU C OE1   1 
ATOM   8401 O OE2   . GLU B 2 742 ? 290.134 189.105 196.685 1.00 117.58 ? 745 GLU C OE2   1 
ATOM   8402 N N     . LYS B 2 743 ? 292.031 189.762 190.751 1.00 118.86 ? 746 LYS C N     1 
ATOM   8403 C CA    . LYS B 2 743 ? 292.671 190.124 189.490 1.00 118.86 ? 746 LYS C CA    1 
ATOM   8404 C C     . LYS B 2 743 ? 292.276 189.170 188.371 1.00 118.86 ? 746 LYS C C     1 
ATOM   8405 O O     . LYS B 2 743 ? 291.938 189.609 187.265 1.00 118.86 ? 746 LYS C O     1 
ATOM   8406 C CB    . LYS B 2 743 ? 294.191 190.138 189.659 1.00 118.86 ? 746 LYS C CB    1 
ATOM   8407 C CG    . LYS B 2 743 ? 294.958 190.133 188.345 1.00 118.86 ? 746 LYS C CG    1 
ATOM   8408 C CD    . LYS B 2 743 ? 296.454 189.973 188.571 1.00 118.86 ? 746 LYS C CD    1 
ATOM   8409 C CE    . LYS B 2 743 ? 296.872 188.513 188.496 1.00 118.86 ? 746 LYS C CE    1 
ATOM   8410 N NZ    . LYS B 2 743 ? 296.845 187.997 187.098 1.00 118.86 ? 746 LYS C NZ    1 
ATOM   8411 N N     . LEU B 2 744 ? 292.318 187.861 188.636 1.00 118.66 ? 747 LEU C N     1 
ATOM   8412 C CA    . LEU B 2 744 ? 291.994 186.882 187.602 1.00 118.66 ? 747 LEU C CA    1 
ATOM   8413 C C     . LEU B 2 744 ? 290.574 187.059 187.092 1.00 118.66 ? 747 LEU C C     1 
ATOM   8414 O O     . LEU B 2 744 ? 290.316 186.885 185.896 1.00 118.66 ? 747 LEU C O     1 
ATOM   8415 C CB    . LEU B 2 744 ? 292.186 185.464 188.144 1.00 118.66 ? 747 LEU C CB    1 
ATOM   8416 C CG    . LEU B 2 744 ? 292.136 184.283 187.170 1.00 118.66 ? 747 LEU C CG    1 
ATOM   8417 C CD1   . LEU B 2 744 ? 293.001 183.167 187.715 1.00 118.66 ? 747 LEU C CD1   1 
ATOM   8418 C CD2   . LEU B 2 744 ? 290.718 183.780 186.934 1.00 118.66 ? 747 LEU C CD2   1 
ATOM   8419 N N     . LEU B 2 745 ? 289.645 187.398 187.980 1.00 118.57 ? 748 LEU C N     1 
ATOM   8420 C CA    . LEU B 2 745 ? 288.259 187.634 187.611 1.00 118.57 ? 748 LEU C CA    1 
ATOM   8421 C C     . LEU B 2 745 ? 288.031 189.043 187.080 1.00 118.57 ? 748 LEU C C     1 
ATOM   8422 O O     . LEU B 2 745 ? 286.968 189.315 186.512 1.00 118.57 ? 748 LEU C O     1 
ATOM   8423 C CB    . LEU B 2 745 ? 287.360 187.360 188.821 1.00 118.57 ? 748 LEU C CB    1 
ATOM   8424 C CG    . LEU B 2 745 ? 285.844 187.373 188.671 1.00 118.57 ? 748 LEU C CG    1 
ATOM   8425 C CD1   . LEU B 2 745 ? 285.421 186.340 187.653 1.00 118.57 ? 748 LEU C CD1   1 
ATOM   8426 C CD2   . LEU B 2 745 ? 285.223 187.067 190.013 1.00 118.57 ? 748 LEU C CD2   1 
ATOM   8427 N N     . GLY B 2 746 ? 289.005 189.934 187.237 1.00 121.49 ? 749 GLY C N     1 
ATOM   8428 C CA    . GLY B 2 746 ? 288.952 191.278 186.706 1.00 121.49 ? 749 GLY C CA    1 
ATOM   8429 C C     . GLY B 2 746 ? 289.358 191.410 185.255 1.00 121.49 ? 749 GLY C C     1 
ATOM   8430 O O     . GLY B 2 746 ? 289.629 192.525 184.797 1.00 121.49 ? 749 GLY C O     1 
ATOM   8431 N N     . SER B 2 747 ? 289.421 190.305 184.520 1.00 121.48 ? 750 SER C N     1 
ATOM   8432 C CA    . SER B 2 747 ? 289.761 190.322 183.106 1.00 121.48 ? 750 SER C CA    1 
ATOM   8433 C C     . SER B 2 747 ? 288.651 189.803 182.208 1.00 121.48 ? 750 SER C C     1 
ATOM   8434 O O     . SER B 2 747 ? 288.594 190.189 181.039 1.00 121.48 ? 750 SER C O     1 
ATOM   8435 C CB    . SER B 2 747 ? 291.031 189.494 182.851 1.00 121.48 ? 750 SER C CB    1 
ATOM   8436 O OG    . SER B 2 747 ? 292.145 190.051 183.526 1.00 121.48 ? 750 SER C OG    1 
ATOM   8437 N N     . LEU B 2 748 ? 287.776 188.941 182.716 1.00 120.15 ? 751 LEU C N     1 
ATOM   8438 C CA    . LEU B 2 748 ? 286.719 188.370 181.896 1.00 120.15 ? 751 LEU C CA    1 
ATOM   8439 C C     . LEU B 2 748 ? 285.657 189.416 181.571 1.00 120.15 ? 751 LEU C C     1 
ATOM   8440 O O     . LEU B 2 748 ? 285.556 190.461 182.220 1.00 120.15 ? 751 LEU C O     1 
ATOM   8441 C CB    . LEU B 2 748 ? 286.077 187.178 182.608 1.00 120.15 ? 751 LEU C CB    1 
ATOM   8442 C CG    . LEU B 2 748 ? 287.019 186.169 183.268 1.00 120.15 ? 751 LEU C CG    1 
ATOM   8443 C CD1   . LEU B 2 748 ? 286.240 184.971 183.780 1.00 120.15 ? 751 LEU C CD1   1 
ATOM   8444 C CD2   . LEU B 2 748 ? 288.106 185.723 182.306 1.00 120.15 ? 751 LEU C CD2   1 
ATOM   8445 N N     . ASP B 2 749 ? 284.861 189.121 180.544 1.00 122.74 ? 752 ASP C N     1 
ATOM   8446 C CA    . ASP B 2 749 ? 283.808 190.039 180.120 1.00 122.74 ? 752 ASP C CA    1 
ATOM   8447 C C     . ASP B 2 749 ? 282.492 189.742 180.834 1.00 122.74 ? 752 ASP C C     1 
ATOM   8448 O O     . ASP B 2 749 ? 281.522 190.498 180.711 1.00 122.74 ? 752 ASP C O     1 
ATOM   8449 C CB    . ASP B 2 749 ? 283.628 189.961 178.603 1.00 122.74 ? 752 ASP C CB    1 
ATOM   8450 C CG    . ASP B 2 749 ? 284.815 190.525 177.845 1.00 122.74 ? 752 ASP C CG    1 
ATOM   8451 O OD1   . ASP B 2 749 ? 285.496 191.422 178.381 1.00 122.74 ? 752 ASP C OD1   1 
ATOM   8452 O OD2   . ASP B 2 749 ? 285.063 190.075 176.707 1.00 122.74 ? 752 ASP C OD2   1 
ATOM   8453 N N     . ILE B 2 750 ? 282.443 188.637 181.581 1.00 119.52 ? 753 ILE C N     1 
ATOM   8454 C CA    . ILE B 2 750 ? 281.197 188.027 182.044 1.00 119.52 ? 753 ILE C CA    1 
ATOM   8455 C C     . ILE B 2 750 ? 280.251 189.005 182.739 1.00 119.52 ? 753 ILE C C     1 
ATOM   8456 O O     . ILE B 2 750 ? 279.154 189.268 182.232 1.00 119.52 ? 753 ILE C O     1 
ATOM   8457 C CB    . ILE B 2 750 ? 281.507 186.814 182.945 1.00 119.52 ? 753 ILE C CB    1 
ATOM   8458 C CG1   . ILE B 2 750 ? 282.473 187.187 184.074 1.00 119.52 ? 753 ILE C CG1   1 
ATOM   8459 C CG2   . ILE B 2 750 ? 282.077 185.676 182.117 1.00 119.52 ? 753 ILE C CG2   1 
ATOM   8460 C CD1   . ILE B 2 750 ? 282.624 186.118 185.123 1.00 119.52 ? 753 ILE C CD1   1 
ATOM   8461 N N     . ASP B 2 751 ? 280.657 189.565 183.878 1.00 115.54 ? 754 ASP C N     1 
ATOM   8462 C CA    . ASP B 2 751 ? 279.818 190.470 184.655 1.00 115.54 ? 754 ASP C CA    1 
ATOM   8463 C C     . ASP B 2 751 ? 280.611 191.009 185.839 1.00 115.54 ? 754 ASP C C     1 
ATOM   8464 O O     . ASP B 2 751 ? 281.826 190.821 185.941 1.00 115.54 ? 754 ASP C O     1 
ATOM   8465 C CB    . ASP B 2 751 ? 278.539 189.775 185.143 1.00 115.54 ? 754 ASP C CB    1 
ATOM   8466 C CG    . ASP B 2 751 ? 277.373 190.734 185.279 1.00 115.54 ? 754 ASP C CG    1 
ATOM   8467 O OD1   . ASP B 2 751 ? 277.572 191.833 185.839 1.00 115.54 ? 754 ASP C OD1   1 
ATOM   8468 O OD2   . ASP B 2 751 ? 276.261 190.394 184.825 1.00 115.54 ? 754 ASP C OD2   1 
ATOM   8469 N N     . HIS B 2 752 ? 279.904 191.696 186.739 1.00 112.97 ? 755 HIS C N     1 
ATOM   8470 C CA    . HIS B 2 752 ? 280.483 192.190 187.978 1.00 112.97 ? 755 HIS C CA    1 
ATOM   8471 C C     . HIS B 2 752 ? 279.671 191.844 189.216 1.00 112.97 ? 755 HIS C C     1 
ATOM   8472 O O     . HIS B 2 752 ? 280.256 191.688 190.291 1.00 112.97 ? 755 HIS C O     1 
ATOM   8473 C CB    . HIS B 2 752 ? 280.657 193.714 187.915 1.00 112.97 ? 755 HIS C CB    1 
ATOM   8474 C CG    . HIS B 2 752 ? 281.666 194.165 186.907 1.00 112.97 ? 755 HIS C CG    1 
ATOM   8475 N ND1   . HIS B 2 752 ? 281.346 194.403 185.588 1.00 112.97 ? 755 HIS C ND1   1 
ATOM   8476 C CD2   . HIS B 2 752 ? 282.989 194.430 187.026 1.00 112.97 ? 755 HIS C CD2   1 
ATOM   8477 C CE1   . HIS B 2 752 ? 282.428 194.790 184.937 1.00 112.97 ? 755 HIS C CE1   1 
ATOM   8478 N NE2   . HIS B 2 752 ? 283.438 194.815 185.787 1.00 112.97 ? 755 HIS C NE2   1 
ATOM   8479 N N     . ASN B 2 753 ? 278.351 191.716 189.093 1.00 111.73 ? 756 ASN C N     1 
ATOM   8480 C CA    . ASN B 2 753 ? 277.482 191.455 190.231 1.00 111.73 ? 756 ASN C CA    1 
ATOM   8481 C C     . ASN B 2 753 ? 277.203 189.975 190.445 1.00 111.73 ? 756 ASN C C     1 
ATOM   8482 O O     . ASN B 2 753 ? 276.695 189.603 191.506 1.00 111.73 ? 756 ASN C O     1 
ATOM   8483 C CB    . ASN B 2 753 ? 276.156 192.204 190.068 1.00 111.73 ? 756 ASN C CB    1 
ATOM   8484 C CG    . ASN B 2 753 ? 275.472 191.901 188.749 1.00 111.73 ? 756 ASN C CG    1 
ATOM   8485 O OD1   . ASN B 2 753 ? 275.917 191.044 187.988 1.00 111.73 ? 756 ASN C OD1   1 
ATOM   8486 N ND2   . ASN B 2 753 ? 274.379 192.604 188.475 1.00 111.73 ? 756 ASN C ND2   1 
ATOM   8487 N N     . GLN B 2 754 ? 277.528 189.123 189.474 1.00 105.72 ? 757 GLN C N     1 
ATOM   8488 C CA    . GLN B 2 754 ? 277.292 187.690 189.602 1.00 105.72 ? 757 GLN C CA    1 
ATOM   8489 C C     . GLN B 2 754 ? 278.257 187.011 190.562 1.00 105.72 ? 757 GLN C C     1 
ATOM   8490 O O     . GLN B 2 754 ? 278.217 185.783 190.688 1.00 105.72 ? 757 GLN C O     1 
ATOM   8491 C CB    . GLN B 2 754 ? 277.378 187.021 188.231 1.00 105.72 ? 757 GLN C CB    1 
ATOM   8492 C CG    . GLN B 2 754 ? 276.380 187.557 187.228 1.00 105.72 ? 757 GLN C CG    1 
ATOM   8493 C CD    . GLN B 2 754 ? 275.129 186.713 187.150 1.00 105.72 ? 757 GLN C CD    1 
ATOM   8494 O OE1   . GLN B 2 754 ? 275.173 185.555 186.736 1.00 105.72 ? 757 GLN C OE1   1 
ATOM   8495 N NE2   . GLN B 2 754 ? 274.002 187.287 187.549 1.00 105.72 ? 757 GLN C NE2   1 
ATOM   8496 N N     . TYR B 2 755 ? 279.120 187.768 191.233 1.00 106.92 ? 758 TYR C N     1 
ATOM   8497 C CA    . TYR B 2 755 ? 280.067 187.207 192.181 1.00 106.92 ? 758 TYR C CA    1 
ATOM   8498 C C     . TYR B 2 755 ? 280.251 188.177 193.337 1.00 106.92 ? 758 TYR C C     1 
ATOM   8499 O O     . TYR B 2 755 ? 279.997 189.377 193.214 1.00 106.92 ? 758 TYR C O     1 
ATOM   8500 C CB    . TYR B 2 755 ? 281.412 186.896 191.511 1.00 106.92 ? 758 TYR C CB    1 
ATOM   8501 C CG    . TYR B 2 755 ? 282.052 188.077 190.815 1.00 106.92 ? 758 TYR C CG    1 
ATOM   8502 C CD1   . TYR B 2 755 ? 282.712 189.064 191.535 1.00 106.92 ? 758 TYR C CD1   1 
ATOM   8503 C CD2   . TYR B 2 755 ? 281.999 188.203 189.435 1.00 106.92 ? 758 TYR C CD2   1 
ATOM   8504 C CE1   . TYR B 2 755 ? 283.298 190.140 190.903 1.00 106.92 ? 758 TYR C CE1   1 
ATOM   8505 C CE2   . TYR B 2 755 ? 282.585 189.276 188.794 1.00 106.92 ? 758 TYR C CE2   1 
ATOM   8506 C CZ    . TYR B 2 755 ? 283.232 190.243 189.535 1.00 106.92 ? 758 TYR C CZ    1 
ATOM   8507 O OH    . TYR B 2 755 ? 283.816 191.318 188.904 1.00 106.92 ? 758 TYR C OH    1 
ATOM   8508 N N     . LYS B 2 756 ? 280.702 187.641 194.469 1.00 101.36 ? 759 LYS C N     1 
ATOM   8509 C CA    . LYS B 2 756 ? 280.969 188.451 195.653 1.00 101.36 ? 759 LYS C CA    1 
ATOM   8510 C C     . LYS B 2 756 ? 282.148 187.838 196.387 1.00 101.36 ? 759 LYS C C     1 
ATOM   8511 O O     . LYS B 2 756 ? 282.225 186.613 196.513 1.00 101.36 ? 759 LYS C O     1 
ATOM   8512 C CB    . LYS B 2 756 ? 279.744 188.527 196.567 1.00 101.36 ? 759 LYS C CB    1 
ATOM   8513 C CG    . LYS B 2 756 ? 278.623 189.404 196.037 1.00 101.36 ? 759 LYS C CG    1 
ATOM   8514 C CD    . LYS B 2 756 ? 277.880 190.117 197.150 1.00 101.36 ? 759 LYS C CD    1 
ATOM   8515 C CE    . LYS B 2 756 ? 277.098 191.301 196.604 1.00 101.36 ? 759 LYS C CE    1 
ATOM   8516 N NZ    . LYS B 2 756 ? 276.319 192.001 197.663 1.00 101.36 ? 759 LYS C NZ    1 
ATOM   8517 N N     . PHE B 2 757 ? 283.066 188.681 196.857 1.00 105.08 ? 760 PHE C N     1 
ATOM   8518 C CA    . PHE B 2 757 ? 284.236 188.218 197.588 1.00 105.08 ? 760 PHE C CA    1 
ATOM   8519 C C     . PHE B 2 757 ? 284.080 188.466 199.081 1.00 105.08 ? 760 PHE C C     1 
ATOM   8520 O O     . PHE B 2 757 ? 283.584 189.515 199.499 1.00 105.08 ? 760 PHE C O     1 
ATOM   8521 C CB    . PHE B 2 757 ? 285.504 188.922 197.104 1.00 105.08 ? 760 PHE C CB    1 
ATOM   8522 C CG    . PHE B 2 757 ? 285.693 188.901 195.622 1.00 105.08 ? 760 PHE C CG    1 
ATOM   8523 C CD1   . PHE B 2 757 ? 286.294 187.823 195.004 1.00 105.08 ? 760 PHE C CD1   1 
ATOM   8524 C CD2   . PHE B 2 757 ? 285.300 189.976 194.848 1.00 105.08 ? 760 PHE C CD2   1 
ATOM   8525 C CE1   . PHE B 2 757 ? 286.479 187.808 193.639 1.00 105.08 ? 760 PHE C CE1   1 
ATOM   8526 C CE2   . PHE B 2 757 ? 285.485 189.967 193.485 1.00 105.08 ? 760 PHE C CE2   1 
ATOM   8527 C CZ    . PHE B 2 757 ? 286.075 188.883 192.880 1.00 105.08 ? 760 PHE C CZ    1 
ATOM   8528 N N     . GLY B 2 758 ? 284.505 187.494 199.881 1.00 104.44 ? 761 GLY C N     1 
ATOM   8529 C CA    . GLY B 2 758 ? 284.698 187.745 201.294 1.00 104.44 ? 761 GLY C CA    1 
ATOM   8530 C C     . GLY B 2 758 ? 285.467 186.668 202.033 1.00 104.44 ? 761 GLY C C     1 
ATOM   8531 O O     . GLY B 2 758 ? 285.103 185.491 201.974 1.00 104.44 ? 761 GLY C O     1 
ATOM   8532 N N     . HIS B 2 759 ? 286.525 187.073 202.737 1.00 103.92 ? 762 HIS C N     1 
ATOM   8533 C CA    . HIS B 2 759 ? 287.207 186.264 203.750 1.00 103.92 ? 762 HIS C CA    1 
ATOM   8534 C C     . HIS B 2 759 ? 287.456 184.828 203.284 1.00 103.92 ? 762 HIS C C     1 
ATOM   8535 O O     . HIS B 2 759 ? 286.902 183.863 203.815 1.00 103.92 ? 762 HIS C O     1 
ATOM   8536 C CB    . HIS B 2 759 ? 286.427 186.288 205.066 1.00 103.92 ? 762 HIS C CB    1 
ATOM   8537 C CG    . HIS B 2 759 ? 286.183 187.666 205.598 1.00 103.92 ? 762 HIS C CG    1 
ATOM   8538 N ND1   . HIS B 2 759 ? 286.589 188.059 206.854 1.00 103.92 ? 762 HIS C ND1   1 
ATOM   8539 C CD2   . HIS B 2 759 ? 285.568 188.740 205.049 1.00 103.92 ? 762 HIS C CD2   1 
ATOM   8540 C CE1   . HIS B 2 759 ? 286.240 189.317 207.054 1.00 103.92 ? 762 HIS C CE1   1 
ATOM   8541 N NE2   . HIS B 2 759 ? 285.618 189.753 205.974 1.00 103.92 ? 762 HIS C NE2   1 
ATOM   8542 N N     . THR B 2 760 ? 288.306 184.705 202.263 1.00 105.36 ? 763 THR C N     1 
ATOM   8543 C CA    . THR B 2 760 ? 288.756 183.406 201.752 1.00 105.36 ? 763 THR C CA    1 
ATOM   8544 C C     . THR B 2 760 ? 287.595 182.579 201.207 1.00 105.36 ? 763 THR C C     1 
ATOM   8545 O O     . THR B 2 760 ? 287.554 181.358 201.365 1.00 105.36 ? 763 THR C O     1 
ATOM   8546 C CB    . THR B 2 760 ? 289.525 182.615 202.816 1.00 105.36 ? 763 THR C CB    1 
ATOM   8547 O OG1   . THR B 2 760 ? 288.601 182.048 203.754 1.00 105.36 ? 763 THR C OG1   1 
ATOM   8548 C CG2   . THR B 2 760 ? 290.520 183.509 203.546 1.00 105.36 ? 763 THR C CG2   1 
ATOM   8549 N N     . LYS B 2 761 ? 286.652 183.249 200.549 1.00 102.02 ? 764 LYS C N     1 
ATOM   8550 C CA    . LYS B 2 761 ? 285.532 182.586 199.894 1.00 102.02 ? 764 LYS C CA    1 
ATOM   8551 C C     . LYS B 2 761 ? 284.980 183.504 198.818 1.00 102.02 ? 764 LYS C C     1 
ATOM   8552 O O     . LYS B 2 761 ? 284.730 184.684 199.076 1.00 102.02 ? 764 LYS C O     1 
ATOM   8553 C CB    . LYS B 2 761 ? 284.423 182.224 200.888 1.00 102.02 ? 764 LYS C CB    1 
ATOM   8554 C CG    . LYS B 2 761 ? 284.544 180.848 201.509 1.00 102.02 ? 764 LYS C CG    1 
ATOM   8555 C CD    . LYS B 2 761 ? 283.871 179.799 200.648 1.00 102.02 ? 764 LYS C CD    1 
ATOM   8556 C CE    . LYS B 2 761 ? 283.739 178.484 201.391 1.00 102.02 ? 764 LYS C CE    1 
ATOM   8557 N NZ    . LYS B 2 761 ? 283.078 178.664 202.712 1.00 102.02 ? 764 LYS C NZ    1 
ATOM   8558 N N     . VAL B 2 762 ? 284.796 182.963 197.619 1.00 99.21  ? 765 VAL C N     1 
ATOM   8559 C CA    . VAL B 2 762 ? 284.141 183.669 196.527 1.00 99.21  ? 765 VAL C CA    1 
ATOM   8560 C C     . VAL B 2 762 ? 282.766 183.051 196.322 1.00 99.21  ? 765 VAL C C     1 
ATOM   8561 O O     . VAL B 2 762 ? 282.603 181.827 196.391 1.00 99.21  ? 765 VAL C O     1 
ATOM   8562 C CB    . VAL B 2 762 ? 284.981 183.637 195.233 1.00 99.21  ? 765 VAL C CB    1 
ATOM   8563 C CG1   . VAL B 2 762 ? 284.968 182.255 194.591 1.00 99.21  ? 765 VAL C CG1   1 
ATOM   8564 C CG2   . VAL B 2 762 ? 284.488 184.691 194.259 1.00 99.21  ? 765 VAL C CG2   1 
ATOM   8565 N N     . PHE B 2 763 ? 281.769 183.902 196.116 1.00 96.01  ? 766 PHE C N     1 
ATOM   8566 C CA    . PHE B 2 763 ? 280.390 183.471 195.961 1.00 96.01  ? 766 PHE C CA    1 
ATOM   8567 C C     . PHE B 2 763 ? 279.959 183.680 194.518 1.00 96.01  ? 766 PHE C C     1 
ATOM   8568 O O     . PHE B 2 763 ? 280.456 184.583 193.840 1.00 96.01  ? 766 PHE C O     1 
ATOM   8569 C CB    . PHE B 2 763 ? 279.469 184.240 196.910 1.00 96.01  ? 766 PHE C CB    1 
ATOM   8570 C CG    . PHE B 2 763 ? 279.641 183.868 198.354 1.00 96.01  ? 766 PHE C CG    1 
ATOM   8571 C CD1   . PHE B 2 763 ? 280.765 184.260 199.056 1.00 96.01  ? 766 PHE C CD1   1 
ATOM   8572 C CD2   . PHE B 2 763 ? 278.674 183.132 199.013 1.00 96.01  ? 766 PHE C CD2   1 
ATOM   8573 C CE1   . PHE B 2 763 ? 280.925 183.918 200.380 1.00 96.01  ? 766 PHE C CE1   1 
ATOM   8574 C CE2   . PHE B 2 763 ? 278.830 182.788 200.341 1.00 96.01  ? 766 PHE C CE2   1 
ATOM   8575 C CZ    . PHE B 2 763 ? 279.956 183.182 201.023 1.00 96.01  ? 766 PHE C CZ    1 
ATOM   8576 N N     . PHE B 2 764 ? 279.048 182.836 194.046 1.00 94.49  ? 767 PHE C N     1 
ATOM   8577 C CA    . PHE B 2 764 ? 278.579 182.892 192.670 1.00 94.49  ? 767 PHE C CA    1 
ATOM   8578 C C     . PHE B 2 764 ? 277.079 182.660 192.624 1.00 94.49  ? 767 PHE C C     1 
ATOM   8579 O O     . PHE B 2 764 ? 276.543 181.861 193.396 1.00 94.49  ? 767 PHE C O     1 
ATOM   8580 C CB    . PHE B 2 764 ? 279.279 181.847 191.800 1.00 94.49  ? 767 PHE C CB    1 
ATOM   8581 C CG    . PHE B 2 764 ? 280.735 182.112 191.586 1.00 94.49  ? 767 PHE C CG    1 
ATOM   8582 C CD1   . PHE B 2 764 ? 281.158 183.285 190.996 1.00 94.49  ? 767 PHE C CD1   1 
ATOM   8583 C CD2   . PHE B 2 764 ? 281.681 181.180 191.965 1.00 94.49  ? 767 PHE C CD2   1 
ATOM   8584 C CE1   . PHE B 2 764 ? 282.497 183.526 190.793 1.00 94.49  ? 767 PHE C CE1   1 
ATOM   8585 C CE2   . PHE B 2 764 ? 283.021 181.417 191.764 1.00 94.49  ? 767 PHE C CE2   1 
ATOM   8586 C CZ    . PHE B 2 764 ? 283.430 182.591 191.179 1.00 94.49  ? 767 PHE C CZ    1 
ATOM   8587 N N     . LYS B 2 765 ? 276.406 183.356 191.714 1.00 92.88  ? 768 LYS C N     1 
ATOM   8588 C CA    . LYS B 2 765 ? 275.007 183.065 191.460 1.00 92.88  ? 768 LYS C CA    1 
ATOM   8589 C C     . LYS B 2 765 ? 274.889 181.835 190.569 1.00 92.88  ? 768 LYS C C     1 
ATOM   8590 O O     . LYS B 2 765 ? 275.848 181.410 189.922 1.00 92.88  ? 768 LYS C O     1 
ATOM   8591 C CB    . LYS B 2 765 ? 274.309 184.260 190.815 1.00 92.88  ? 768 LYS C CB    1 
ATOM   8592 C CG    . LYS B 2 765 ? 274.034 185.399 191.776 1.00 92.88  ? 768 LYS C CG    1 
ATOM   8593 C CD    . LYS B 2 765 ? 273.015 186.373 191.212 1.00 92.88  ? 768 LYS C CD    1 
ATOM   8594 C CE    . LYS B 2 765 ? 272.427 187.242 192.313 1.00 92.88  ? 768 LYS C CE    1 
ATOM   8595 N NZ    . LYS B 2 765 ? 271.471 188.255 191.789 1.00 92.88  ? 768 LYS C NZ    1 
ATOM   8596 N N     . ALA B 2 766 ? 273.693 181.257 190.547 1.00 92.73  ? 769 ALA C N     1 
ATOM   8597 C CA    . ALA B 2 766 ? 273.463 180.019 189.812 1.00 92.73  ? 769 ALA C CA    1 
ATOM   8598 C C     . ALA B 2 766 ? 273.597 180.278 188.318 1.00 92.73  ? 769 ALA C C     1 
ATOM   8599 O O     . ALA B 2 766 ? 272.727 180.906 187.707 1.00 92.73  ? 769 ALA C O     1 
ATOM   8600 C CB    . ALA B 2 766 ? 272.087 179.455 190.147 1.00 92.73  ? 769 ALA C CB    1 
ATOM   8601 N N     . GLY B 2 767 ? 274.686 179.798 187.725 1.00 94.14  ? 770 GLY C N     1 
ATOM   8602 C CA    . GLY B 2 767 ? 274.850 179.885 186.290 1.00 94.14  ? 770 GLY C CA    1 
ATOM   8603 C C     . GLY B 2 767 ? 276.135 180.538 185.830 1.00 94.14  ? 770 GLY C C     1 
ATOM   8604 O O     . GLY B 2 767 ? 276.354 180.689 184.625 1.00 94.14  ? 770 GLY C O     1 
ATOM   8605 N N     . LEU B 2 768 ? 276.999 180.927 186.765 1.00 95.53  ? 771 LEU C N     1 
ATOM   8606 C CA    . LEU B 2 768 ? 278.277 181.515 186.390 1.00 95.53  ? 771 LEU C CA    1 
ATOM   8607 C C     . LEU B 2 768 ? 279.405 180.497 186.342 1.00 95.53  ? 771 LEU C C     1 
ATOM   8608 O O     . LEU B 2 768 ? 280.288 180.609 185.486 1.00 95.53  ? 771 LEU C O     1 
ATOM   8609 C CB    . LEU B 2 768 ? 278.652 182.651 187.348 1.00 95.53  ? 771 LEU C CB    1 
ATOM   8610 C CG    . LEU B 2 768 ? 279.868 183.461 186.896 1.00 95.53  ? 771 LEU C CG    1 
ATOM   8611 C CD1   . LEU B 2 768 ? 279.578 184.106 185.558 1.00 95.53  ? 771 LEU C CD1   1 
ATOM   8612 C CD2   . LEU B 2 768 ? 280.232 184.518 187.910 1.00 95.53  ? 771 LEU C CD2   1 
ATOM   8613 N N     . LEU B 2 769 ? 279.396 179.498 187.224 1.00 95.24  ? 772 LEU C N     1 
ATOM   8614 C CA    . LEU B 2 769 ? 280.339 178.394 187.102 1.00 95.24  ? 772 LEU C CA    1 
ATOM   8615 C C     . LEU B 2 769 ? 279.913 177.375 186.057 1.00 95.24  ? 772 LEU C C     1 
ATOM   8616 O O     . LEU B 2 769 ? 280.622 176.383 185.857 1.00 95.24  ? 772 LEU C O     1 
ATOM   8617 C CB    . LEU B 2 769 ? 280.528 177.697 188.451 1.00 95.24  ? 772 LEU C CB    1 
ATOM   8618 C CG    . LEU B 2 769 ? 281.241 178.502 189.535 1.00 95.24  ? 772 LEU C CG    1 
ATOM   8619 C CD1   . LEU B 2 769 ? 281.730 177.588 190.640 1.00 95.24  ? 772 LEU C CD1   1 
ATOM   8620 C CD2   . LEU B 2 769 ? 282.397 179.281 188.938 1.00 95.24  ? 772 LEU C CD2   1 
ATOM   8621 N N     . GLY B 2 770 ? 278.775 177.584 185.400 1.00 96.15  ? 773 GLY C N     1 
ATOM   8622 C CA    . GLY B 2 770 ? 278.399 176.764 184.267 1.00 96.15  ? 773 GLY C CA    1 
ATOM   8623 C C     . GLY B 2 770 ? 278.899 177.273 182.939 1.00 96.15  ? 773 GLY C C     1 
ATOM   8624 O O     . GLY B 2 770 ? 278.979 176.502 181.979 1.00 96.15  ? 773 GLY C O     1 
ATOM   8625 N N     . LEU B 2 771 ? 279.234 178.562 182.866 1.00 99.31  ? 774 LEU C N     1 
ATOM   8626 C CA    . LEU B 2 771 ? 279.873 179.112 181.678 1.00 99.31  ? 774 LEU C CA    1 
ATOM   8627 C C     . LEU B 2 771 ? 281.346 178.733 181.626 1.00 99.31  ? 774 LEU C C     1 
ATOM   8628 O O     . LEU B 2 771 ? 281.879 178.442 180.550 1.00 99.31  ? 774 LEU C O     1 
ATOM   8629 C CB    . LEU B 2 771 ? 279.709 180.631 181.658 1.00 99.31  ? 774 LEU C CB    1 
ATOM   8630 C CG    . LEU B 2 771 ? 280.059 181.349 180.357 1.00 99.31  ? 774 LEU C CG    1 
ATOM   8631 C CD1   . LEU B 2 771 ? 278.886 181.301 179.392 1.00 99.31  ? 774 LEU C CD1   1 
ATOM   8632 C CD2   . LEU B 2 771 ? 280.466 182.785 180.638 1.00 99.31  ? 774 LEU C CD2   1 
ATOM   8633 N N     . LEU B 2 772 ? 282.009 178.725 182.776 1.00 97.66  ? 775 LEU C N     1 
ATOM   8634 C CA    . LEU B 2 772 ? 283.404 178.321 182.869 1.00 97.66  ? 775 LEU C CA    1 
ATOM   8635 C C     . LEU B 2 772 ? 283.538 176.809 182.744 1.00 97.66  ? 775 LEU C C     1 
ATOM   8636 O O     . LEU B 2 772 ? 283.865 176.120 183.707 1.00 97.66  ? 775 LEU C O     1 
ATOM   8637 C CB    . LEU B 2 772 ? 284.009 178.794 184.191 1.00 97.66  ? 775 LEU C CB    1 
ATOM   8638 C CG    . LEU B 2 772 ? 284.453 180.256 184.299 1.00 97.66  ? 775 LEU C CG    1 
ATOM   8639 C CD1   . LEU B 2 772 ? 283.271 181.208 184.331 1.00 97.66  ? 775 LEU C CD1   1 
ATOM   8640 C CD2   . LEU B 2 772 ? 285.315 180.448 185.535 1.00 97.66  ? 775 LEU C CD2   1 
ATOM   8641 O OXT   . LEU B 2 772 ? 283.319 176.235 181.679 1.00 97.66  ? 775 LEU C OXT   1 
HETATM 8642 P PB    . ADP C 3 .   ? 213.329 190.186 230.498 1.00 55.87  ? 401 ADP J PB    1 
HETATM 8643 O O1B   . ADP C 3 .   ? 214.327 189.679 229.490 1.00 55.87  ? 401 ADP J O1B   1 
HETATM 8644 O O2B   . ADP C 3 .   ? 212.602 191.435 230.078 1.00 55.87  ? 401 ADP J O2B   1 
HETATM 8645 O O3B   . ADP C 3 .   ? 213.814 190.205 231.921 1.00 55.87  ? 401 ADP J O3B   1 
HETATM 8646 P PA    . ADP C 3 .   ? 212.545 187.516 230.720 1.00 55.87  ? 401 ADP J PA    1 
HETATM 8647 O O1A   . ADP C 3 .   ? 212.581 186.824 229.384 1.00 55.87  ? 401 ADP J O1A   1 
HETATM 8648 O O2A   . ADP C 3 .   ? 213.714 187.443 231.661 1.00 55.87  ? 401 ADP J O2A   1 
HETATM 8649 O O3A   . ADP C 3 .   ? 212.188 189.064 230.496 1.00 55.87  ? 401 ADP J O3A   1 
HETATM 8650 O "O5'" . ADP C 3 .   ? 211.230 187.048 231.505 1.00 55.87  ? 401 ADP J "O5'" 1 
HETATM 8651 C "C5'" . ADP C 3 .   ? 211.138 187.176 232.920 1.00 55.87  ? 401 ADP J "C5'" 1 
HETATM 8652 C "C4'" . ADP C 3 .   ? 209.665 187.094 233.290 1.00 55.87  ? 401 ADP J "C4'" 1 
HETATM 8653 O "O4'" . ADP C 3 .   ? 209.150 185.826 232.898 1.00 55.87  ? 401 ADP J "O4'" 1 
HETATM 8654 C "C3'" . ADP C 3 .   ? 209.429 187.224 234.780 1.00 55.87  ? 401 ADP J "C3'" 1 
HETATM 8655 O "O3'" . ADP C 3 .   ? 208.761 188.455 235.048 1.00 55.87  ? 401 ADP J "O3'" 1 
HETATM 8656 C "C2'" . ADP C 3 .   ? 208.517 186.082 235.160 1.00 55.87  ? 401 ADP J "C2'" 1 
HETATM 8657 O "O2'" . ADP C 3 .   ? 207.301 186.610 235.687 1.00 55.87  ? 401 ADP J "O2'" 1 
HETATM 8658 C "C1'" . ADP C 3 .   ? 208.231 185.343 233.871 1.00 55.87  ? 401 ADP J "C1'" 1 
HETATM 8659 N N9    . ADP C 3 .   ? 208.445 183.895 234.062 1.00 55.87  ? 401 ADP J N9    1 
HETATM 8660 C C8    . ADP C 3 .   ? 209.624 183.306 234.306 1.00 55.87  ? 401 ADP J C8    1 
HETATM 8661 N N7    . ADP C 3 .   ? 209.481 181.964 234.430 1.00 55.87  ? 401 ADP J N7    1 
HETATM 8662 C C5    . ADP C 3 .   ? 208.179 181.685 234.264 1.00 55.87  ? 401 ADP J C5    1 
HETATM 8663 C C6    . ADP C 3 .   ? 207.345 180.468 234.271 1.00 55.87  ? 401 ADP J C6    1 
HETATM 8664 N N6    . ADP C 3 .   ? 207.894 179.252 234.487 1.00 55.87  ? 401 ADP J N6    1 
HETATM 8665 N N1    . ADP C 3 .   ? 206.022 180.613 234.058 1.00 55.87  ? 401 ADP J N1    1 
HETATM 8666 C C2    . ADP C 3 .   ? 205.469 181.817 233.841 1.00 55.87  ? 401 ADP J C2    1 
HETATM 8667 N N3    . ADP C 3 .   ? 206.166 182.963 233.820 1.00 55.87  ? 401 ADP J N3    1 
HETATM 8668 C C4    . ADP C 3 .   ? 207.500 182.961 234.025 1.00 55.87  ? 401 ADP J C4    1 
# 
