data_8ZI9
# 
_entry.id   8ZI9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ZI9         pdb_00008zi9 10.2210/pdb8zi9/pdb 
WWPDB D_1300047815 ?            ?                   
EMDB  EMD-60122    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-29 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ZI9 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Human left ventricle actin and myosin complex' 
_pdbx_database_related.db_id          EMD-60122 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              dannielee@sjtu.edu.cn 
_pdbx_contact_author.name_first         Cong 
_pdbx_contact_author.name_last          Liu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3425-6672 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, D.N.'   1 ? 
'Zhao, Q.Y.' 2 ? 
'Liu, C.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Human left ventricle actin and myosin complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, D.N.'   1 ? 
primary 'Zhao, Q.Y.' 2 ? 
primary 'Liu, C.'    3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     nat Myosin-7                        88412.180 1 ?       ? ? ? 
2 polymer     nat 'Actin, alpha cardiac muscle 1' 41342.145 1 3.6.4.- ? ? ? 
3 non-polymer syn "ADENOSINE-5'-DIPHOSPHATE"      427.201   1 ?       ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta' 
2 'Alpha-cardiac actin'                                                                                                     
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFD
KIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYM
LTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFG
KFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDD
AEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVK
VGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKL
QQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQK
PRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQ
TVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL
NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL
;
;MAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFD
KIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYM
LTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFG
KFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDD
AEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVK
VGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKL
QQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQK
PRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQ
TVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL
NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL
;
M ? 
2 'polypeptide(L)' no no 
;TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEK
IWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVP
IYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPD
GQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPST
MKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
;
;TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEK
IWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVP
IYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPD
GQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPST
MKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
;
F ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        "ADENOSINE-5'-DIPHOSPHATE" 
_pdbx_entity_nonpoly.comp_id     ADP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   VAL n 
1 4   PHE n 
1 5   GLY n 
1 6   ALA n 
1 7   ALA n 
1 8   ALA n 
1 9   PRO n 
1 10  TYR n 
1 11  LEU n 
1 12  ARG n 
1 13  LYS n 
1 14  SER n 
1 15  GLU n 
1 16  LYS n 
1 17  GLU n 
1 18  ARG n 
1 19  LEU n 
1 20  GLU n 
1 21  ALA n 
1 22  GLN n 
1 23  THR n 
1 24  ARG n 
1 25  PRO n 
1 26  PHE n 
1 27  ASP n 
1 28  LEU n 
1 29  LYS n 
1 30  LYS n 
1 31  ASP n 
1 32  VAL n 
1 33  PHE n 
1 34  VAL n 
1 35  PRO n 
1 36  ASP n 
1 37  ASP n 
1 38  LYS n 
1 39  GLN n 
1 40  GLU n 
1 41  PHE n 
1 42  VAL n 
1 43  LYS n 
1 44  ALA n 
1 45  LYS n 
1 46  ILE n 
1 47  VAL n 
1 48  SER n 
1 49  ARG n 
1 50  GLU n 
1 51  GLY n 
1 52  GLY n 
1 53  LYS n 
1 54  VAL n 
1 55  THR n 
1 56  ALA n 
1 57  GLU n 
1 58  THR n 
1 59  GLU n 
1 60  TYR n 
1 61  GLY n 
1 62  LYS n 
1 63  THR n 
1 64  VAL n 
1 65  THR n 
1 66  VAL n 
1 67  LYS n 
1 68  GLU n 
1 69  ASP n 
1 70  GLN n 
1 71  VAL n 
1 72  MET n 
1 73  GLN n 
1 74  GLN n 
1 75  ASN n 
1 76  PRO n 
1 77  PRO n 
1 78  LYS n 
1 79  PHE n 
1 80  ASP n 
1 81  LYS n 
1 82  ILE n 
1 83  GLU n 
1 84  ASP n 
1 85  MET n 
1 86  ALA n 
1 87  MET n 
1 88  LEU n 
1 89  THR n 
1 90  PHE n 
1 91  LEU n 
1 92  HIS n 
1 93  GLU n 
1 94  PRO n 
1 95  ALA n 
1 96  VAL n 
1 97  LEU n 
1 98  TYR n 
1 99  ASN n 
1 100 LEU n 
1 101 LYS n 
1 102 ASP n 
1 103 ARG n 
1 104 TYR n 
1 105 GLY n 
1 106 SER n 
1 107 TRP n 
1 108 MET n 
1 109 ILE n 
1 110 TYR n 
1 111 THR n 
1 112 TYR n 
1 113 SER n 
1 114 GLY n 
1 115 LEU n 
1 116 PHE n 
1 117 CYS n 
1 118 VAL n 
1 119 THR n 
1 120 VAL n 
1 121 ASN n 
1 122 PRO n 
1 123 TYR n 
1 124 LYS n 
1 125 TRP n 
1 126 LEU n 
1 127 PRO n 
1 128 VAL n 
1 129 TYR n 
1 130 THR n 
1 131 PRO n 
1 132 GLU n 
1 133 VAL n 
1 134 VAL n 
1 135 ALA n 
1 136 ALA n 
1 137 TYR n 
1 138 ARG n 
1 139 GLY n 
1 140 LYS n 
1 141 LYS n 
1 142 ARG n 
1 143 SER n 
1 144 GLU n 
1 145 ALA n 
1 146 PRO n 
1 147 PRO n 
1 148 HIS n 
1 149 ILE n 
1 150 PHE n 
1 151 SER n 
1 152 ILE n 
1 153 SER n 
1 154 ASP n 
1 155 ASN n 
1 156 ALA n 
1 157 TYR n 
1 158 GLN n 
1 159 TYR n 
1 160 MET n 
1 161 LEU n 
1 162 THR n 
1 163 ASP n 
1 164 ARG n 
1 165 GLU n 
1 166 ASN n 
1 167 GLN n 
1 168 SER n 
1 169 ILE n 
1 170 LEU n 
1 171 ILE n 
1 172 THR n 
1 173 GLY n 
1 174 GLU n 
1 175 SER n 
1 176 GLY n 
1 177 ALA n 
1 178 GLY n 
1 179 LYS n 
1 180 THR n 
1 181 VAL n 
1 182 ASN n 
1 183 THR n 
1 184 LYS n 
1 185 ARG n 
1 186 VAL n 
1 187 ILE n 
1 188 GLN n 
1 189 TYR n 
1 190 PHE n 
1 191 ALA n 
1 192 VAL n 
1 193 ILE n 
1 194 ALA n 
1 195 ALA n 
1 196 ILE n 
1 197 GLY n 
1 198 ASP n 
1 199 ARG n 
1 200 SER n 
1 201 LYS n 
1 202 LYS n 
1 203 ASP n 
1 204 GLN n 
1 205 SER n 
1 206 PRO n 
1 207 GLY n 
1 208 LYS n 
1 209 GLY n 
1 210 THR n 
1 211 LEU n 
1 212 GLU n 
1 213 ASP n 
1 214 GLN n 
1 215 ILE n 
1 216 ILE n 
1 217 GLN n 
1 218 ALA n 
1 219 ASN n 
1 220 PRO n 
1 221 ALA n 
1 222 LEU n 
1 223 GLU n 
1 224 ALA n 
1 225 PHE n 
1 226 GLY n 
1 227 ASN n 
1 228 ALA n 
1 229 LYS n 
1 230 THR n 
1 231 VAL n 
1 232 ARG n 
1 233 ASN n 
1 234 ASP n 
1 235 ASN n 
1 236 SER n 
1 237 SER n 
1 238 ARG n 
1 239 PHE n 
1 240 GLY n 
1 241 LYS n 
1 242 PHE n 
1 243 ILE n 
1 244 ARG n 
1 245 ILE n 
1 246 HIS n 
1 247 PHE n 
1 248 GLY n 
1 249 ALA n 
1 250 THR n 
1 251 GLY n 
1 252 LYS n 
1 253 LEU n 
1 254 ALA n 
1 255 SER n 
1 256 ALA n 
1 257 ASP n 
1 258 ILE n 
1 259 GLU n 
1 260 THR n 
1 261 TYR n 
1 262 LEU n 
1 263 LEU n 
1 264 GLU n 
1 265 LYS n 
1 266 SER n 
1 267 ARG n 
1 268 VAL n 
1 269 ILE n 
1 270 PHE n 
1 271 GLN n 
1 272 LEU n 
1 273 LYS n 
1 274 ALA n 
1 275 GLU n 
1 276 ARG n 
1 277 ASP n 
1 278 TYR n 
1 279 HIS n 
1 280 ILE n 
1 281 PHE n 
1 282 TYR n 
1 283 GLN n 
1 284 ILE n 
1 285 LEU n 
1 286 SER n 
1 287 ASN n 
1 288 LYS n 
1 289 LYS n 
1 290 PRO n 
1 291 GLU n 
1 292 LEU n 
1 293 LEU n 
1 294 ASP n 
1 295 MET n 
1 296 LEU n 
1 297 LEU n 
1 298 ILE n 
1 299 THR n 
1 300 ASN n 
1 301 ASN n 
1 302 PRO n 
1 303 TYR n 
1 304 ASP n 
1 305 TYR n 
1 306 ALA n 
1 307 PHE n 
1 308 ILE n 
1 309 SER n 
1 310 GLN n 
1 311 GLY n 
1 312 GLU n 
1 313 THR n 
1 314 THR n 
1 315 VAL n 
1 316 ALA n 
1 317 SER n 
1 318 ILE n 
1 319 ASP n 
1 320 ASP n 
1 321 ALA n 
1 322 GLU n 
1 323 GLU n 
1 324 LEU n 
1 325 MET n 
1 326 ALA n 
1 327 THR n 
1 328 ASP n 
1 329 ASN n 
1 330 ALA n 
1 331 PHE n 
1 332 ASP n 
1 333 VAL n 
1 334 LEU n 
1 335 GLY n 
1 336 PHE n 
1 337 THR n 
1 338 SER n 
1 339 GLU n 
1 340 GLU n 
1 341 LYS n 
1 342 ASN n 
1 343 SER n 
1 344 MET n 
1 345 TYR n 
1 346 LYS n 
1 347 LEU n 
1 348 THR n 
1 349 GLY n 
1 350 ALA n 
1 351 ILE n 
1 352 MET n 
1 353 HIS n 
1 354 PHE n 
1 355 GLY n 
1 356 ASN n 
1 357 MET n 
1 358 LYS n 
1 359 PHE n 
1 360 LYS n 
1 361 LEU n 
1 362 LYS n 
1 363 GLN n 
1 364 ARG n 
1 365 GLU n 
1 366 GLU n 
1 367 GLN n 
1 368 ALA n 
1 369 GLU n 
1 370 PRO n 
1 371 ASP n 
1 372 GLY n 
1 373 THR n 
1 374 GLU n 
1 375 GLU n 
1 376 ALA n 
1 377 ASP n 
1 378 LYS n 
1 379 SER n 
1 380 ALA n 
1 381 TYR n 
1 382 LEU n 
1 383 MET n 
1 384 GLY n 
1 385 LEU n 
1 386 ASN n 
1 387 SER n 
1 388 ALA n 
1 389 ASP n 
1 390 LEU n 
1 391 LEU n 
1 392 LYS n 
1 393 GLY n 
1 394 LEU n 
1 395 CYS n 
1 396 HIS n 
1 397 PRO n 
1 398 ARG n 
1 399 VAL n 
1 400 LYS n 
1 401 VAL n 
1 402 GLY n 
1 403 ASN n 
1 404 GLU n 
1 405 TYR n 
1 406 VAL n 
1 407 THR n 
1 408 LYS n 
1 409 GLY n 
1 410 GLN n 
1 411 ASN n 
1 412 VAL n 
1 413 GLN n 
1 414 GLN n 
1 415 VAL n 
1 416 ILE n 
1 417 TYR n 
1 418 ALA n 
1 419 THR n 
1 420 GLY n 
1 421 ALA n 
1 422 LEU n 
1 423 ALA n 
1 424 LYS n 
1 425 ALA n 
1 426 VAL n 
1 427 TYR n 
1 428 GLU n 
1 429 ARG n 
1 430 MET n 
1 431 PHE n 
1 432 ASN n 
1 433 TRP n 
1 434 MET n 
1 435 VAL n 
1 436 THR n 
1 437 ARG n 
1 438 ILE n 
1 439 ASN n 
1 440 ALA n 
1 441 THR n 
1 442 LEU n 
1 443 GLU n 
1 444 THR n 
1 445 LYS n 
1 446 GLN n 
1 447 PRO n 
1 448 ARG n 
1 449 GLN n 
1 450 TYR n 
1 451 PHE n 
1 452 ILE n 
1 453 GLY n 
1 454 VAL n 
1 455 LEU n 
1 456 ASP n 
1 457 ILE n 
1 458 ALA n 
1 459 GLY n 
1 460 PHE n 
1 461 GLU n 
1 462 ILE n 
1 463 PHE n 
1 464 ASP n 
1 465 PHE n 
1 466 ASN n 
1 467 SER n 
1 468 PHE n 
1 469 GLU n 
1 470 GLN n 
1 471 LEU n 
1 472 CYS n 
1 473 ILE n 
1 474 ASN n 
1 475 PHE n 
1 476 THR n 
1 477 ASN n 
1 478 GLU n 
1 479 LYS n 
1 480 LEU n 
1 481 GLN n 
1 482 GLN n 
1 483 PHE n 
1 484 PHE n 
1 485 ASN n 
1 486 HIS n 
1 487 HIS n 
1 488 MET n 
1 489 PHE n 
1 490 VAL n 
1 491 LEU n 
1 492 GLU n 
1 493 GLN n 
1 494 GLU n 
1 495 GLU n 
1 496 TYR n 
1 497 LYS n 
1 498 LYS n 
1 499 GLU n 
1 500 GLY n 
1 501 ILE n 
1 502 GLU n 
1 503 TRP n 
1 504 THR n 
1 505 PHE n 
1 506 ILE n 
1 507 ASP n 
1 508 PHE n 
1 509 GLY n 
1 510 MET n 
1 511 ASP n 
1 512 LEU n 
1 513 GLN n 
1 514 ALA n 
1 515 CYS n 
1 516 ILE n 
1 517 ASP n 
1 518 LEU n 
1 519 ILE n 
1 520 GLU n 
1 521 LYS n 
1 522 PRO n 
1 523 MET n 
1 524 GLY n 
1 525 ILE n 
1 526 MET n 
1 527 SER n 
1 528 ILE n 
1 529 LEU n 
1 530 GLU n 
1 531 GLU n 
1 532 GLU n 
1 533 CYS n 
1 534 MET n 
1 535 PHE n 
1 536 PRO n 
1 537 LYS n 
1 538 ALA n 
1 539 THR n 
1 540 ASP n 
1 541 MET n 
1 542 THR n 
1 543 PHE n 
1 544 LYS n 
1 545 ALA n 
1 546 LYS n 
1 547 LEU n 
1 548 PHE n 
1 549 ASP n 
1 550 ASN n 
1 551 HIS n 
1 552 LEU n 
1 553 GLY n 
1 554 LYS n 
1 555 SER n 
1 556 ALA n 
1 557 ASN n 
1 558 PHE n 
1 559 GLN n 
1 560 LYS n 
1 561 PRO n 
1 562 ARG n 
1 563 ASN n 
1 564 ILE n 
1 565 LYS n 
1 566 GLY n 
1 567 LYS n 
1 568 PRO n 
1 569 GLU n 
1 570 ALA n 
1 571 HIS n 
1 572 PHE n 
1 573 SER n 
1 574 LEU n 
1 575 ILE n 
1 576 HIS n 
1 577 TYR n 
1 578 ALA n 
1 579 GLY n 
1 580 ILE n 
1 581 VAL n 
1 582 ASP n 
1 583 TYR n 
1 584 ASN n 
1 585 ILE n 
1 586 ILE n 
1 587 GLY n 
1 588 TRP n 
1 589 LEU n 
1 590 GLN n 
1 591 LYS n 
1 592 ASN n 
1 593 LYS n 
1 594 ASP n 
1 595 PRO n 
1 596 LEU n 
1 597 ASN n 
1 598 GLU n 
1 599 THR n 
1 600 VAL n 
1 601 VAL n 
1 602 GLY n 
1 603 LEU n 
1 604 TYR n 
1 605 GLN n 
1 606 LYS n 
1 607 SER n 
1 608 SER n 
1 609 LEU n 
1 610 LYS n 
1 611 LEU n 
1 612 LEU n 
1 613 SER n 
1 614 THR n 
1 615 LEU n 
1 616 PHE n 
1 617 ALA n 
1 618 ASN n 
1 619 TYR n 
1 620 ALA n 
1 621 GLY n 
1 622 ALA n 
1 623 ASP n 
1 624 ALA n 
1 625 PRO n 
1 626 ILE n 
1 627 GLU n 
1 628 LYS n 
1 629 GLY n 
1 630 LYS n 
1 631 GLY n 
1 632 LYS n 
1 633 ALA n 
1 634 LYS n 
1 635 LYS n 
1 636 GLY n 
1 637 SER n 
1 638 SER n 
1 639 PHE n 
1 640 GLN n 
1 641 THR n 
1 642 VAL n 
1 643 SER n 
1 644 ALA n 
1 645 LEU n 
1 646 HIS n 
1 647 ARG n 
1 648 GLU n 
1 649 ASN n 
1 650 LEU n 
1 651 ASN n 
1 652 LYS n 
1 653 LEU n 
1 654 MET n 
1 655 THR n 
1 656 ASN n 
1 657 LEU n 
1 658 ARG n 
1 659 SER n 
1 660 THR n 
1 661 HIS n 
1 662 PRO n 
1 663 HIS n 
1 664 PHE n 
1 665 VAL n 
1 666 ARG n 
1 667 CYS n 
1 668 ILE n 
1 669 ILE n 
1 670 PRO n 
1 671 ASN n 
1 672 GLU n 
1 673 THR n 
1 674 LYS n 
1 675 SER n 
1 676 PRO n 
1 677 GLY n 
1 678 VAL n 
1 679 MET n 
1 680 ASP n 
1 681 ASN n 
1 682 PRO n 
1 683 LEU n 
1 684 VAL n 
1 685 MET n 
1 686 HIS n 
1 687 GLN n 
1 688 LEU n 
1 689 ARG n 
1 690 CYS n 
1 691 ASN n 
1 692 GLY n 
1 693 VAL n 
1 694 LEU n 
1 695 GLU n 
1 696 GLY n 
1 697 ILE n 
1 698 ARG n 
1 699 ILE n 
1 700 CYS n 
1 701 ARG n 
1 702 LYS n 
1 703 GLY n 
1 704 PHE n 
1 705 PRO n 
1 706 ASN n 
1 707 ARG n 
1 708 ILE n 
1 709 LEU n 
1 710 TYR n 
1 711 GLY n 
1 712 ASP n 
1 713 PHE n 
1 714 ARG n 
1 715 GLN n 
1 716 ARG n 
1 717 TYR n 
1 718 ARG n 
1 719 ILE n 
1 720 LEU n 
1 721 ASN n 
1 722 PRO n 
1 723 ALA n 
1 724 ALA n 
1 725 ILE n 
1 726 PRO n 
1 727 GLU n 
1 728 GLY n 
1 729 GLN n 
1 730 PHE n 
1 731 ILE n 
1 732 ASP n 
1 733 SER n 
1 734 ARG n 
1 735 LYS n 
1 736 GLY n 
1 737 ALA n 
1 738 GLU n 
1 739 LYS n 
1 740 LEU n 
1 741 LEU n 
1 742 SER n 
1 743 SER n 
1 744 LEU n 
1 745 ASP n 
1 746 ILE n 
1 747 ASP n 
1 748 HIS n 
1 749 ASN n 
1 750 GLN n 
1 751 TYR n 
1 752 LYS n 
1 753 PHE n 
1 754 GLY n 
1 755 HIS n 
1 756 THR n 
1 757 LYS n 
1 758 VAL n 
1 759 PHE n 
1 760 PHE n 
1 761 LYS n 
1 762 ALA n 
1 763 GLY n 
1 764 LEU n 
1 765 LEU n 
1 766 GLY n 
1 767 LEU n 
1 768 LEU n 
1 769 GLU n 
1 770 GLU n 
1 771 MET n 
1 772 ARG n 
1 773 ASP n 
1 774 GLU n 
1 775 ARG n 
1 776 LEU n 
2 1   THR n 
2 2   THR n 
2 3   ALA n 
2 4   LEU n 
2 5   VAL n 
2 6   CYS n 
2 7   ASP n 
2 8   ASN n 
2 9   GLY n 
2 10  SER n 
2 11  GLY n 
2 12  LEU n 
2 13  VAL n 
2 14  LYS n 
2 15  ALA n 
2 16  GLY n 
2 17  PHE n 
2 18  ALA n 
2 19  GLY n 
2 20  ASP n 
2 21  ASP n 
2 22  ALA n 
2 23  PRO n 
2 24  ARG n 
2 25  ALA n 
2 26  VAL n 
2 27  PHE n 
2 28  PRO n 
2 29  SER n 
2 30  ILE n 
2 31  VAL n 
2 32  GLY n 
2 33  ARG n 
2 34  PRO n 
2 35  ARG n 
2 36  HIS n 
2 37  GLN n 
2 38  GLY n 
2 39  VAL n 
2 40  MET n 
2 41  VAL n 
2 42  GLY n 
2 43  MET n 
2 44  GLY n 
2 45  GLN n 
2 46  LYS n 
2 47  ASP n 
2 48  SER n 
2 49  TYR n 
2 50  VAL n 
2 51  GLY n 
2 52  ASP n 
2 53  GLU n 
2 54  ALA n 
2 55  GLN n 
2 56  SER n 
2 57  LYS n 
2 58  ARG n 
2 59  GLY n 
2 60  ILE n 
2 61  LEU n 
2 62  THR n 
2 63  LEU n 
2 64  LYS n 
2 65  TYR n 
2 66  PRO n 
2 67  ILE n 
2 68  GLU n 
2 69  HIS n 
2 70  GLY n 
2 71  ILE n 
2 72  ILE n 
2 73  THR n 
2 74  ASN n 
2 75  TRP n 
2 76  ASP n 
2 77  ASP n 
2 78  MET n 
2 79  GLU n 
2 80  LYS n 
2 81  ILE n 
2 82  TRP n 
2 83  HIS n 
2 84  HIS n 
2 85  THR n 
2 86  PHE n 
2 87  TYR n 
2 88  ASN n 
2 89  GLU n 
2 90  LEU n 
2 91  ARG n 
2 92  VAL n 
2 93  ALA n 
2 94  PRO n 
2 95  GLU n 
2 96  GLU n 
2 97  HIS n 
2 98  PRO n 
2 99  THR n 
2 100 LEU n 
2 101 LEU n 
2 102 THR n 
2 103 GLU n 
2 104 ALA n 
2 105 PRO n 
2 106 LEU n 
2 107 ASN n 
2 108 PRO n 
2 109 LYS n 
2 110 ALA n 
2 111 ASN n 
2 112 ARG n 
2 113 GLU n 
2 114 LYS n 
2 115 MET n 
2 116 THR n 
2 117 GLN n 
2 118 ILE n 
2 119 MET n 
2 120 PHE n 
2 121 GLU n 
2 122 THR n 
2 123 PHE n 
2 124 ASN n 
2 125 VAL n 
2 126 PRO n 
2 127 ALA n 
2 128 MET n 
2 129 TYR n 
2 130 VAL n 
2 131 ALA n 
2 132 ILE n 
2 133 GLN n 
2 134 ALA n 
2 135 VAL n 
2 136 LEU n 
2 137 SER n 
2 138 LEU n 
2 139 TYR n 
2 140 ALA n 
2 141 SER n 
2 142 GLY n 
2 143 ARG n 
2 144 THR n 
2 145 THR n 
2 146 GLY n 
2 147 ILE n 
2 148 VAL n 
2 149 LEU n 
2 150 ASP n 
2 151 SER n 
2 152 GLY n 
2 153 ASP n 
2 154 GLY n 
2 155 VAL n 
2 156 THR n 
2 157 HIS n 
2 158 ASN n 
2 159 VAL n 
2 160 PRO n 
2 161 ILE n 
2 162 TYR n 
2 163 GLU n 
2 164 GLY n 
2 165 TYR n 
2 166 ALA n 
2 167 LEU n 
2 168 PRO n 
2 169 HIS n 
2 170 ALA n 
2 171 ILE n 
2 172 MET n 
2 173 ARG n 
2 174 LEU n 
2 175 ASP n 
2 176 LEU n 
2 177 ALA n 
2 178 GLY n 
2 179 ARG n 
2 180 ASP n 
2 181 LEU n 
2 182 THR n 
2 183 ASP n 
2 184 TYR n 
2 185 LEU n 
2 186 MET n 
2 187 LYS n 
2 188 ILE n 
2 189 LEU n 
2 190 THR n 
2 191 GLU n 
2 192 ARG n 
2 193 GLY n 
2 194 TYR n 
2 195 SER n 
2 196 PHE n 
2 197 VAL n 
2 198 THR n 
2 199 THR n 
2 200 ALA n 
2 201 GLU n 
2 202 ARG n 
2 203 GLU n 
2 204 ILE n 
2 205 VAL n 
2 206 ARG n 
2 207 ASP n 
2 208 ILE n 
2 209 LYS n 
2 210 GLU n 
2 211 LYS n 
2 212 LEU n 
2 213 CYS n 
2 214 TYR n 
2 215 VAL n 
2 216 ALA n 
2 217 LEU n 
2 218 ASP n 
2 219 PHE n 
2 220 GLU n 
2 221 ASN n 
2 222 GLU n 
2 223 MET n 
2 224 ALA n 
2 225 THR n 
2 226 ALA n 
2 227 ALA n 
2 228 SER n 
2 229 SER n 
2 230 SER n 
2 231 SER n 
2 232 LEU n 
2 233 GLU n 
2 234 LYS n 
2 235 SER n 
2 236 TYR n 
2 237 GLU n 
2 238 LEU n 
2 239 PRO n 
2 240 ASP n 
2 241 GLY n 
2 242 GLN n 
2 243 VAL n 
2 244 ILE n 
2 245 THR n 
2 246 ILE n 
2 247 GLY n 
2 248 ASN n 
2 249 GLU n 
2 250 ARG n 
2 251 PHE n 
2 252 ARG n 
2 253 CYS n 
2 254 PRO n 
2 255 GLU n 
2 256 THR n 
2 257 LEU n 
2 258 PHE n 
2 259 GLN n 
2 260 PRO n 
2 261 SER n 
2 262 PHE n 
2 263 ILE n 
2 264 GLY n 
2 265 MET n 
2 266 GLU n 
2 267 SER n 
2 268 ALA n 
2 269 GLY n 
2 270 ILE n 
2 271 HIS n 
2 272 GLU n 
2 273 THR n 
2 274 THR n 
2 275 TYR n 
2 276 ASN n 
2 277 SER n 
2 278 ILE n 
2 279 MET n 
2 280 LYS n 
2 281 CYS n 
2 282 ASP n 
2 283 ILE n 
2 284 ASP n 
2 285 ILE n 
2 286 ARG n 
2 287 LYS n 
2 288 ASP n 
2 289 LEU n 
2 290 TYR n 
2 291 ALA n 
2 292 ASN n 
2 293 ASN n 
2 294 VAL n 
2 295 LEU n 
2 296 SER n 
2 297 GLY n 
2 298 GLY n 
2 299 THR n 
2 300 THR n 
2 301 MET n 
2 302 TYR n 
2 303 PRO n 
2 304 GLY n 
2 305 ILE n 
2 306 ALA n 
2 307 ASP n 
2 308 ARG n 
2 309 MET n 
2 310 GLN n 
2 311 LYS n 
2 312 GLU n 
2 313 ILE n 
2 314 THR n 
2 315 ALA n 
2 316 LEU n 
2 317 ALA n 
2 318 PRO n 
2 319 SER n 
2 320 THR n 
2 321 MET n 
2 322 LYS n 
2 323 ILE n 
2 324 LYS n 
2 325 ILE n 
2 326 ILE n 
2 327 ALA n 
2 328 PRO n 
2 329 PRO n 
2 330 GLU n 
2 331 ARG n 
2 332 LYS n 
2 333 TYR n 
2 334 SER n 
2 335 VAL n 
2 336 TRP n 
2 337 ILE n 
2 338 GLY n 
2 339 GLY n 
2 340 SER n 
2 341 ILE n 
2 342 LEU n 
2 343 ALA n 
2 344 SER n 
2 345 LEU n 
2 346 SER n 
2 347 THR n 
2 348 PHE n 
2 349 GLN n 
2 350 GLN n 
2 351 MET n 
2 352 TRP n 
2 353 ILE n 
2 354 SER n 
2 355 LYS n 
2 356 GLN n 
2 357 GLU n 
2 358 TYR n 
2 359 ASP n 
2 360 GLU n 
2 361 ALA n 
2 362 GLY n 
2 363 PRO n 
2 364 SER n 
2 365 ILE n 
2 366 VAL n 
2 367 HIS n 
2 368 ARG n 
2 369 LYS n 
2 370 CYS n 
2 371 PHE n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 776 human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 371 human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ADP non-polymer         n "ADENOSINE-5'-DIPHOSPHATE" ? 'C10 H15 N5 O10 P2' 427.201 
ALA 'L-peptide linking' y ALANINE                    ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                   ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                 ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'            ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                   ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                  ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'            ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                    ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                  ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                 ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                    ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                     ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                 ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE              ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                    ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                     ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                  ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                 ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                   ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                     ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   6   6   MET MET M . n 
A 1 2   ALA 2   7   7   ALA ALA M . n 
A 1 3   VAL 3   8   8   VAL VAL M . n 
A 1 4   PHE 4   9   9   PHE PHE M . n 
A 1 5   GLY 5   10  10  GLY GLY M . n 
A 1 6   ALA 6   11  11  ALA ALA M . n 
A 1 7   ALA 7   12  12  ALA ALA M . n 
A 1 8   ALA 8   13  13  ALA ALA M . n 
A 1 9   PRO 9   14  14  PRO PRO M . n 
A 1 10  TYR 10  15  15  TYR TYR M . n 
A 1 11  LEU 11  16  16  LEU LEU M . n 
A 1 12  ARG 12  17  17  ARG ARG M . n 
A 1 13  LYS 13  18  18  LYS LYS M . n 
A 1 14  SER 14  19  19  SER SER M . n 
A 1 15  GLU 15  20  20  GLU GLU M . n 
A 1 16  LYS 16  21  21  LYS LYS M . n 
A 1 17  GLU 17  22  22  GLU GLU M . n 
A 1 18  ARG 18  23  23  ARG ARG M . n 
A 1 19  LEU 19  24  24  LEU LEU M . n 
A 1 20  GLU 20  25  25  GLU GLU M . n 
A 1 21  ALA 21  26  26  ALA ALA M . n 
A 1 22  GLN 22  27  27  GLN GLN M . n 
A 1 23  THR 23  28  28  THR THR M . n 
A 1 24  ARG 24  29  29  ARG ARG M . n 
A 1 25  PRO 25  30  30  PRO PRO M . n 
A 1 26  PHE 26  31  31  PHE PHE M . n 
A 1 27  ASP 27  32  32  ASP ASP M . n 
A 1 28  LEU 28  33  33  LEU LEU M . n 
A 1 29  LYS 29  34  34  LYS LYS M . n 
A 1 30  LYS 30  35  35  LYS LYS M . n 
A 1 31  ASP 31  36  36  ASP ASP M . n 
A 1 32  VAL 32  37  37  VAL VAL M . n 
A 1 33  PHE 33  38  38  PHE PHE M . n 
A 1 34  VAL 34  39  39  VAL VAL M . n 
A 1 35  PRO 35  40  40  PRO PRO M . n 
A 1 36  ASP 36  41  41  ASP ASP M . n 
A 1 37  ASP 37  42  42  ASP ASP M . n 
A 1 38  LYS 38  43  43  LYS LYS M . n 
A 1 39  GLN 39  44  44  GLN GLN M . n 
A 1 40  GLU 40  45  45  GLU GLU M . n 
A 1 41  PHE 41  46  46  PHE PHE M . n 
A 1 42  VAL 42  47  47  VAL VAL M . n 
A 1 43  LYS 43  48  48  LYS LYS M . n 
A 1 44  ALA 44  49  49  ALA ALA M . n 
A 1 45  LYS 45  50  50  LYS LYS M . n 
A 1 46  ILE 46  51  51  ILE ILE M . n 
A 1 47  VAL 47  52  52  VAL VAL M . n 
A 1 48  SER 48  53  53  SER SER M . n 
A 1 49  ARG 49  54  54  ARG ARG M . n 
A 1 50  GLU 50  55  55  GLU GLU M . n 
A 1 51  GLY 51  56  56  GLY GLY M . n 
A 1 52  GLY 52  57  57  GLY GLY M . n 
A 1 53  LYS 53  58  58  LYS LYS M . n 
A 1 54  VAL 54  59  59  VAL VAL M . n 
A 1 55  THR 55  60  60  THR THR M . n 
A 1 56  ALA 56  61  61  ALA ALA M . n 
A 1 57  GLU 57  62  62  GLU GLU M . n 
A 1 58  THR 58  63  63  THR THR M . n 
A 1 59  GLU 59  64  64  GLU GLU M . n 
A 1 60  TYR 60  65  65  TYR TYR M . n 
A 1 61  GLY 61  66  66  GLY GLY M . n 
A 1 62  LYS 62  67  67  LYS LYS M . n 
A 1 63  THR 63  68  68  THR THR M . n 
A 1 64  VAL 64  69  69  VAL VAL M . n 
A 1 65  THR 65  70  70  THR THR M . n 
A 1 66  VAL 66  71  71  VAL VAL M . n 
A 1 67  LYS 67  72  72  LYS LYS M . n 
A 1 68  GLU 68  73  73  GLU GLU M . n 
A 1 69  ASP 69  74  74  ASP ASP M . n 
A 1 70  GLN 70  75  75  GLN GLN M . n 
A 1 71  VAL 71  76  76  VAL VAL M . n 
A 1 72  MET 72  77  77  MET MET M . n 
A 1 73  GLN 73  78  78  GLN GLN M . n 
A 1 74  GLN 74  79  79  GLN GLN M . n 
A 1 75  ASN 75  80  80  ASN ASN M . n 
A 1 76  PRO 76  81  81  PRO PRO M . n 
A 1 77  PRO 77  82  82  PRO PRO M . n 
A 1 78  LYS 78  83  83  LYS LYS M . n 
A 1 79  PHE 79  84  84  PHE PHE M . n 
A 1 80  ASP 80  85  85  ASP ASP M . n 
A 1 81  LYS 81  86  86  LYS LYS M . n 
A 1 82  ILE 82  87  87  ILE ILE M . n 
A 1 83  GLU 83  88  88  GLU GLU M . n 
A 1 84  ASP 84  89  89  ASP ASP M . n 
A 1 85  MET 85  90  90  MET MET M . n 
A 1 86  ALA 86  91  91  ALA ALA M . n 
A 1 87  MET 87  92  92  MET MET M . n 
A 1 88  LEU 88  93  93  LEU LEU M . n 
A 1 89  THR 89  94  94  THR THR M . n 
A 1 90  PHE 90  95  95  PHE PHE M . n 
A 1 91  LEU 91  96  96  LEU LEU M . n 
A 1 92  HIS 92  97  97  HIS HIS M . n 
A 1 93  GLU 93  98  98  GLU GLU M . n 
A 1 94  PRO 94  99  99  PRO PRO M . n 
A 1 95  ALA 95  100 100 ALA ALA M . n 
A 1 96  VAL 96  101 101 VAL VAL M . n 
A 1 97  LEU 97  102 102 LEU LEU M . n 
A 1 98  TYR 98  103 103 TYR TYR M . n 
A 1 99  ASN 99  104 104 ASN ASN M . n 
A 1 100 LEU 100 105 105 LEU LEU M . n 
A 1 101 LYS 101 106 106 LYS LYS M . n 
A 1 102 ASP 102 107 107 ASP ASP M . n 
A 1 103 ARG 103 108 108 ARG ARG M . n 
A 1 104 TYR 104 109 109 TYR TYR M . n 
A 1 105 GLY 105 110 110 GLY GLY M . n 
A 1 106 SER 106 111 111 SER SER M . n 
A 1 107 TRP 107 112 112 TRP TRP M . n 
A 1 108 MET 108 113 113 MET MET M . n 
A 1 109 ILE 109 114 114 ILE ILE M . n 
A 1 110 TYR 110 115 115 TYR TYR M . n 
A 1 111 THR 111 116 116 THR THR M . n 
A 1 112 TYR 112 117 117 TYR TYR M . n 
A 1 113 SER 113 118 118 SER SER M . n 
A 1 114 GLY 114 119 119 GLY GLY M . n 
A 1 115 LEU 115 120 120 LEU LEU M . n 
A 1 116 PHE 116 121 121 PHE PHE M . n 
A 1 117 CYS 117 122 122 CYS CYS M . n 
A 1 118 VAL 118 123 123 VAL VAL M . n 
A 1 119 THR 119 124 124 THR THR M . n 
A 1 120 VAL 120 125 125 VAL VAL M . n 
A 1 121 ASN 121 126 126 ASN ASN M . n 
A 1 122 PRO 122 127 127 PRO PRO M . n 
A 1 123 TYR 123 128 128 TYR TYR M . n 
A 1 124 LYS 124 129 129 LYS LYS M . n 
A 1 125 TRP 125 130 130 TRP TRP M . n 
A 1 126 LEU 126 131 131 LEU LEU M . n 
A 1 127 PRO 127 132 132 PRO PRO M . n 
A 1 128 VAL 128 133 133 VAL VAL M . n 
A 1 129 TYR 129 134 134 TYR TYR M . n 
A 1 130 THR 130 135 135 THR THR M . n 
A 1 131 PRO 131 136 136 PRO PRO M . n 
A 1 132 GLU 132 137 137 GLU GLU M . n 
A 1 133 VAL 133 138 138 VAL VAL M . n 
A 1 134 VAL 134 139 139 VAL VAL M . n 
A 1 135 ALA 135 140 140 ALA ALA M . n 
A 1 136 ALA 136 141 141 ALA ALA M . n 
A 1 137 TYR 137 142 142 TYR TYR M . n 
A 1 138 ARG 138 143 143 ARG ARG M . n 
A 1 139 GLY 139 144 144 GLY GLY M . n 
A 1 140 LYS 140 145 145 LYS LYS M . n 
A 1 141 LYS 141 146 146 LYS LYS M . n 
A 1 142 ARG 142 147 147 ARG ARG M . n 
A 1 143 SER 143 148 148 SER SER M . n 
A 1 144 GLU 144 149 149 GLU GLU M . n 
A 1 145 ALA 145 150 150 ALA ALA M . n 
A 1 146 PRO 146 151 151 PRO PRO M . n 
A 1 147 PRO 147 152 152 PRO PRO M . n 
A 1 148 HIS 148 153 153 HIS HIS M . n 
A 1 149 ILE 149 154 154 ILE ILE M . n 
A 1 150 PHE 150 155 155 PHE PHE M . n 
A 1 151 SER 151 156 156 SER SER M . n 
A 1 152 ILE 152 157 157 ILE ILE M . n 
A 1 153 SER 153 158 158 SER SER M . n 
A 1 154 ASP 154 159 159 ASP ASP M . n 
A 1 155 ASN 155 160 160 ASN ASN M . n 
A 1 156 ALA 156 161 161 ALA ALA M . n 
A 1 157 TYR 157 162 162 TYR TYR M . n 
A 1 158 GLN 158 163 163 GLN GLN M . n 
A 1 159 TYR 159 164 164 TYR TYR M . n 
A 1 160 MET 160 165 165 MET MET M . n 
A 1 161 LEU 161 166 166 LEU LEU M . n 
A 1 162 THR 162 167 167 THR THR M . n 
A 1 163 ASP 163 168 168 ASP ASP M . n 
A 1 164 ARG 164 169 169 ARG ARG M . n 
A 1 165 GLU 165 170 170 GLU GLU M . n 
A 1 166 ASN 166 171 171 ASN ASN M . n 
A 1 167 GLN 167 172 172 GLN GLN M . n 
A 1 168 SER 168 173 173 SER SER M . n 
A 1 169 ILE 169 174 174 ILE ILE M . n 
A 1 170 LEU 170 175 175 LEU LEU M . n 
A 1 171 ILE 171 176 176 ILE ILE M . n 
A 1 172 THR 172 177 177 THR THR M . n 
A 1 173 GLY 173 178 178 GLY GLY M . n 
A 1 174 GLU 174 179 179 GLU GLU M . n 
A 1 175 SER 175 180 180 SER SER M . n 
A 1 176 GLY 176 181 181 GLY GLY M . n 
A 1 177 ALA 177 182 182 ALA ALA M . n 
A 1 178 GLY 178 183 183 GLY GLY M . n 
A 1 179 LYS 179 184 184 LYS LYS M . n 
A 1 180 THR 180 185 185 THR THR M . n 
A 1 181 VAL 181 186 186 VAL VAL M . n 
A 1 182 ASN 182 187 187 ASN ASN M . n 
A 1 183 THR 183 188 188 THR THR M . n 
A 1 184 LYS 184 189 189 LYS LYS M . n 
A 1 185 ARG 185 190 190 ARG ARG M . n 
A 1 186 VAL 186 191 191 VAL VAL M . n 
A 1 187 ILE 187 192 192 ILE ILE M . n 
A 1 188 GLN 188 193 193 GLN GLN M . n 
A 1 189 TYR 189 194 194 TYR TYR M . n 
A 1 190 PHE 190 195 195 PHE PHE M . n 
A 1 191 ALA 191 196 196 ALA ALA M . n 
A 1 192 VAL 192 197 197 VAL VAL M . n 
A 1 193 ILE 193 198 198 ILE ILE M . n 
A 1 194 ALA 194 199 199 ALA ALA M . n 
A 1 195 ALA 195 200 ?   ?   ?   M . n 
A 1 196 ILE 196 201 ?   ?   ?   M . n 
A 1 197 GLY 197 202 ?   ?   ?   M . n 
A 1 198 ASP 198 203 ?   ?   ?   M . n 
A 1 199 ARG 199 204 ?   ?   ?   M . n 
A 1 200 SER 200 205 ?   ?   ?   M . n 
A 1 201 LYS 201 206 ?   ?   ?   M . n 
A 1 202 LYS 202 207 ?   ?   ?   M . n 
A 1 203 ASP 203 208 ?   ?   ?   M . n 
A 1 204 GLN 204 209 ?   ?   ?   M . n 
A 1 205 SER 205 210 ?   ?   ?   M . n 
A 1 206 PRO 206 211 ?   ?   ?   M . n 
A 1 207 GLY 207 212 ?   ?   ?   M . n 
A 1 208 LYS 208 213 ?   ?   ?   M . n 
A 1 209 GLY 209 214 ?   ?   ?   M . n 
A 1 210 THR 210 215 ?   ?   ?   M . n 
A 1 211 LEU 211 216 216 LEU LEU M . n 
A 1 212 GLU 212 217 217 GLU GLU M . n 
A 1 213 ASP 213 218 218 ASP ASP M . n 
A 1 214 GLN 214 219 219 GLN GLN M . n 
A 1 215 ILE 215 220 220 ILE ILE M . n 
A 1 216 ILE 216 221 221 ILE ILE M . n 
A 1 217 GLN 217 222 222 GLN GLN M . n 
A 1 218 ALA 218 223 223 ALA ALA M . n 
A 1 219 ASN 219 224 224 ASN ASN M . n 
A 1 220 PRO 220 225 225 PRO PRO M . n 
A 1 221 ALA 221 226 226 ALA ALA M . n 
A 1 222 LEU 222 227 227 LEU LEU M . n 
A 1 223 GLU 223 228 228 GLU GLU M . n 
A 1 224 ALA 224 229 229 ALA ALA M . n 
A 1 225 PHE 225 230 230 PHE PHE M . n 
A 1 226 GLY 226 231 231 GLY GLY M . n 
A 1 227 ASN 227 232 232 ASN ASN M . n 
A 1 228 ALA 228 233 233 ALA ALA M . n 
A 1 229 LYS 229 234 234 LYS LYS M . n 
A 1 230 THR 230 235 235 THR THR M . n 
A 1 231 VAL 231 236 236 VAL VAL M . n 
A 1 232 ARG 232 237 237 ARG ARG M . n 
A 1 233 ASN 233 238 238 ASN ASN M . n 
A 1 234 ASP 234 239 239 ASP ASP M . n 
A 1 235 ASN 235 240 240 ASN ASN M . n 
A 1 236 SER 236 241 241 SER SER M . n 
A 1 237 SER 237 242 242 SER SER M . n 
A 1 238 ARG 238 243 243 ARG ARG M . n 
A 1 239 PHE 239 244 244 PHE PHE M . n 
A 1 240 GLY 240 245 245 GLY GLY M . n 
A 1 241 LYS 241 246 246 LYS LYS M . n 
A 1 242 PHE 242 247 247 PHE PHE M . n 
A 1 243 ILE 243 248 248 ILE ILE M . n 
A 1 244 ARG 244 249 249 ARG ARG M . n 
A 1 245 ILE 245 250 250 ILE ILE M . n 
A 1 246 HIS 246 251 251 HIS HIS M . n 
A 1 247 PHE 247 252 252 PHE PHE M . n 
A 1 248 GLY 248 253 253 GLY GLY M . n 
A 1 249 ALA 249 254 254 ALA ALA M . n 
A 1 250 THR 250 255 255 THR THR M . n 
A 1 251 GLY 251 256 256 GLY GLY M . n 
A 1 252 LYS 252 257 257 LYS LYS M . n 
A 1 253 LEU 253 258 258 LEU LEU M . n 
A 1 254 ALA 254 259 259 ALA ALA M . n 
A 1 255 SER 255 260 260 SER SER M . n 
A 1 256 ALA 256 261 261 ALA ALA M . n 
A 1 257 ASP 257 262 262 ASP ASP M . n 
A 1 258 ILE 258 263 263 ILE ILE M . n 
A 1 259 GLU 259 264 264 GLU GLU M . n 
A 1 260 THR 260 265 265 THR THR M . n 
A 1 261 TYR 261 266 266 TYR TYR M . n 
A 1 262 LEU 262 267 267 LEU LEU M . n 
A 1 263 LEU 263 268 268 LEU LEU M . n 
A 1 264 GLU 264 269 269 GLU GLU M . n 
A 1 265 LYS 265 270 270 LYS LYS M . n 
A 1 266 SER 266 271 271 SER SER M . n 
A 1 267 ARG 267 272 272 ARG ARG M . n 
A 1 268 VAL 268 273 273 VAL VAL M . n 
A 1 269 ILE 269 274 274 ILE ILE M . n 
A 1 270 PHE 270 275 275 PHE PHE M . n 
A 1 271 GLN 271 276 276 GLN GLN M . n 
A 1 272 LEU 272 277 277 LEU LEU M . n 
A 1 273 LYS 273 278 278 LYS LYS M . n 
A 1 274 ALA 274 279 279 ALA ALA M . n 
A 1 275 GLU 275 280 280 GLU GLU M . n 
A 1 276 ARG 276 281 281 ARG ARG M . n 
A 1 277 ASP 277 282 282 ASP ASP M . n 
A 1 278 TYR 278 283 283 TYR TYR M . n 
A 1 279 HIS 279 284 284 HIS HIS M . n 
A 1 280 ILE 280 285 285 ILE ILE M . n 
A 1 281 PHE 281 286 286 PHE PHE M . n 
A 1 282 TYR 282 287 287 TYR TYR M . n 
A 1 283 GLN 283 288 288 GLN GLN M . n 
A 1 284 ILE 284 289 289 ILE ILE M . n 
A 1 285 LEU 285 290 290 LEU LEU M . n 
A 1 286 SER 286 291 291 SER SER M . n 
A 1 287 ASN 287 292 292 ASN ASN M . n 
A 1 288 LYS 288 293 293 LYS LYS M . n 
A 1 289 LYS 289 294 294 LYS LYS M . n 
A 1 290 PRO 290 295 295 PRO PRO M . n 
A 1 291 GLU 291 296 296 GLU GLU M . n 
A 1 292 LEU 292 297 297 LEU LEU M . n 
A 1 293 LEU 293 298 298 LEU LEU M . n 
A 1 294 ASP 294 299 299 ASP ASP M . n 
A 1 295 MET 295 300 300 MET MET M . n 
A 1 296 LEU 296 301 301 LEU LEU M . n 
A 1 297 LEU 297 302 302 LEU LEU M . n 
A 1 298 ILE 298 303 303 ILE ILE M . n 
A 1 299 THR 299 304 304 THR THR M . n 
A 1 300 ASN 300 305 305 ASN ASN M . n 
A 1 301 ASN 301 306 306 ASN ASN M . n 
A 1 302 PRO 302 307 307 PRO PRO M . n 
A 1 303 TYR 303 308 308 TYR TYR M . n 
A 1 304 ASP 304 309 309 ASP ASP M . n 
A 1 305 TYR 305 310 310 TYR TYR M . n 
A 1 306 ALA 306 311 311 ALA ALA M . n 
A 1 307 PHE 307 312 312 PHE PHE M . n 
A 1 308 ILE 308 313 313 ILE ILE M . n 
A 1 309 SER 309 314 314 SER SER M . n 
A 1 310 GLN 310 315 315 GLN GLN M . n 
A 1 311 GLY 311 316 316 GLY GLY M . n 
A 1 312 GLU 312 317 317 GLU GLU M . n 
A 1 313 THR 313 318 318 THR THR M . n 
A 1 314 THR 314 319 319 THR THR M . n 
A 1 315 VAL 315 320 320 VAL VAL M . n 
A 1 316 ALA 316 321 321 ALA ALA M . n 
A 1 317 SER 317 322 322 SER SER M . n 
A 1 318 ILE 318 323 323 ILE ILE M . n 
A 1 319 ASP 319 324 324 ASP ASP M . n 
A 1 320 ASP 320 325 325 ASP ASP M . n 
A 1 321 ALA 321 326 326 ALA ALA M . n 
A 1 322 GLU 322 327 327 GLU GLU M . n 
A 1 323 GLU 323 328 328 GLU GLU M . n 
A 1 324 LEU 324 329 329 LEU LEU M . n 
A 1 325 MET 325 330 330 MET MET M . n 
A 1 326 ALA 326 331 331 ALA ALA M . n 
A 1 327 THR 327 332 332 THR THR M . n 
A 1 328 ASP 328 333 333 ASP ASP M . n 
A 1 329 ASN 329 334 334 ASN ASN M . n 
A 1 330 ALA 330 335 335 ALA ALA M . n 
A 1 331 PHE 331 336 336 PHE PHE M . n 
A 1 332 ASP 332 337 337 ASP ASP M . n 
A 1 333 VAL 333 338 338 VAL VAL M . n 
A 1 334 LEU 334 339 339 LEU LEU M . n 
A 1 335 GLY 335 340 340 GLY GLY M . n 
A 1 336 PHE 336 341 341 PHE PHE M . n 
A 1 337 THR 337 342 342 THR THR M . n 
A 1 338 SER 338 343 343 SER SER M . n 
A 1 339 GLU 339 344 344 GLU GLU M . n 
A 1 340 GLU 340 345 345 GLU GLU M . n 
A 1 341 LYS 341 346 346 LYS LYS M . n 
A 1 342 ASN 342 347 347 ASN ASN M . n 
A 1 343 SER 343 348 348 SER SER M . n 
A 1 344 MET 344 349 349 MET MET M . n 
A 1 345 TYR 345 350 350 TYR TYR M . n 
A 1 346 LYS 346 351 351 LYS LYS M . n 
A 1 347 LEU 347 352 352 LEU LEU M . n 
A 1 348 THR 348 353 353 THR THR M . n 
A 1 349 GLY 349 354 354 GLY GLY M . n 
A 1 350 ALA 350 355 355 ALA ALA M . n 
A 1 351 ILE 351 356 356 ILE ILE M . n 
A 1 352 MET 352 357 357 MET MET M . n 
A 1 353 HIS 353 358 358 HIS HIS M . n 
A 1 354 PHE 354 359 359 PHE PHE M . n 
A 1 355 GLY 355 360 360 GLY GLY M . n 
A 1 356 ASN 356 361 361 ASN ASN M . n 
A 1 357 MET 357 362 362 MET MET M . n 
A 1 358 LYS 358 363 363 LYS LYS M . n 
A 1 359 PHE 359 364 364 PHE PHE M . n 
A 1 360 LYS 360 365 365 LYS LYS M . n 
A 1 361 LEU 361 366 366 LEU LEU M . n 
A 1 362 LYS 362 367 367 LYS LYS M . n 
A 1 363 GLN 363 368 368 GLN GLN M . n 
A 1 364 ARG 364 369 369 ARG ARG M . n 
A 1 365 GLU 365 370 370 GLU GLU M . n 
A 1 366 GLU 366 371 371 GLU GLU M . n 
A 1 367 GLN 367 372 372 GLN GLN M . n 
A 1 368 ALA 368 373 373 ALA ALA M . n 
A 1 369 GLU 369 374 374 GLU GLU M . n 
A 1 370 PRO 370 375 375 PRO PRO M . n 
A 1 371 ASP 371 376 376 ASP ASP M . n 
A 1 372 GLY 372 377 377 GLY GLY M . n 
A 1 373 THR 373 378 378 THR THR M . n 
A 1 374 GLU 374 379 379 GLU GLU M . n 
A 1 375 GLU 375 380 380 GLU GLU M . n 
A 1 376 ALA 376 381 381 ALA ALA M . n 
A 1 377 ASP 377 382 382 ASP ASP M . n 
A 1 378 LYS 378 383 383 LYS LYS M . n 
A 1 379 SER 379 384 384 SER SER M . n 
A 1 380 ALA 380 385 385 ALA ALA M . n 
A 1 381 TYR 381 386 386 TYR TYR M . n 
A 1 382 LEU 382 387 387 LEU LEU M . n 
A 1 383 MET 383 388 388 MET MET M . n 
A 1 384 GLY 384 389 389 GLY GLY M . n 
A 1 385 LEU 385 390 390 LEU LEU M . n 
A 1 386 ASN 386 391 391 ASN ASN M . n 
A 1 387 SER 387 392 392 SER SER M . n 
A 1 388 ALA 388 393 393 ALA ALA M . n 
A 1 389 ASP 389 394 394 ASP ASP M . n 
A 1 390 LEU 390 395 395 LEU LEU M . n 
A 1 391 LEU 391 396 396 LEU LEU M . n 
A 1 392 LYS 392 397 397 LYS LYS M . n 
A 1 393 GLY 393 398 398 GLY GLY M . n 
A 1 394 LEU 394 399 399 LEU LEU M . n 
A 1 395 CYS 395 400 400 CYS CYS M . n 
A 1 396 HIS 396 401 401 HIS HIS M . n 
A 1 397 PRO 397 402 402 PRO PRO M . n 
A 1 398 ARG 398 403 403 ARG ARG M . n 
A 1 399 VAL 399 404 404 VAL VAL M . n 
A 1 400 LYS 400 405 405 LYS LYS M . n 
A 1 401 VAL 401 406 406 VAL VAL M . n 
A 1 402 GLY 402 407 407 GLY GLY M . n 
A 1 403 ASN 403 408 408 ASN ASN M . n 
A 1 404 GLU 404 409 409 GLU GLU M . n 
A 1 405 TYR 405 410 410 TYR TYR M . n 
A 1 406 VAL 406 411 411 VAL VAL M . n 
A 1 407 THR 407 412 412 THR THR M . n 
A 1 408 LYS 408 413 413 LYS LYS M . n 
A 1 409 GLY 409 414 414 GLY GLY M . n 
A 1 410 GLN 410 415 415 GLN GLN M . n 
A 1 411 ASN 411 416 416 ASN ASN M . n 
A 1 412 VAL 412 417 417 VAL VAL M . n 
A 1 413 GLN 413 418 418 GLN GLN M . n 
A 1 414 GLN 414 419 419 GLN GLN M . n 
A 1 415 VAL 415 420 420 VAL VAL M . n 
A 1 416 ILE 416 421 421 ILE ILE M . n 
A 1 417 TYR 417 422 422 TYR TYR M . n 
A 1 418 ALA 418 423 423 ALA ALA M . n 
A 1 419 THR 419 424 424 THR THR M . n 
A 1 420 GLY 420 425 425 GLY GLY M . n 
A 1 421 ALA 421 426 426 ALA ALA M . n 
A 1 422 LEU 422 427 427 LEU LEU M . n 
A 1 423 ALA 423 428 428 ALA ALA M . n 
A 1 424 LYS 424 429 429 LYS LYS M . n 
A 1 425 ALA 425 430 430 ALA ALA M . n 
A 1 426 VAL 426 431 431 VAL VAL M . n 
A 1 427 TYR 427 432 432 TYR TYR M . n 
A 1 428 GLU 428 433 433 GLU GLU M . n 
A 1 429 ARG 429 434 434 ARG ARG M . n 
A 1 430 MET 430 435 435 MET MET M . n 
A 1 431 PHE 431 436 436 PHE PHE M . n 
A 1 432 ASN 432 437 437 ASN ASN M . n 
A 1 433 TRP 433 438 438 TRP TRP M . n 
A 1 434 MET 434 439 439 MET MET M . n 
A 1 435 VAL 435 440 440 VAL VAL M . n 
A 1 436 THR 436 441 441 THR THR M . n 
A 1 437 ARG 437 442 442 ARG ARG M . n 
A 1 438 ILE 438 443 443 ILE ILE M . n 
A 1 439 ASN 439 444 444 ASN ASN M . n 
A 1 440 ALA 440 445 445 ALA ALA M . n 
A 1 441 THR 441 446 446 THR THR M . n 
A 1 442 LEU 442 447 447 LEU LEU M . n 
A 1 443 GLU 443 448 448 GLU GLU M . n 
A 1 444 THR 444 449 449 THR THR M . n 
A 1 445 LYS 445 450 450 LYS LYS M . n 
A 1 446 GLN 446 451 451 GLN GLN M . n 
A 1 447 PRO 447 452 452 PRO PRO M . n 
A 1 448 ARG 448 453 453 ARG ARG M . n 
A 1 449 GLN 449 454 454 GLN GLN M . n 
A 1 450 TYR 450 455 455 TYR TYR M . n 
A 1 451 PHE 451 456 456 PHE PHE M . n 
A 1 452 ILE 452 457 457 ILE ILE M . n 
A 1 453 GLY 453 458 458 GLY GLY M . n 
A 1 454 VAL 454 459 459 VAL VAL M . n 
A 1 455 LEU 455 460 460 LEU LEU M . n 
A 1 456 ASP 456 461 461 ASP ASP M . n 
A 1 457 ILE 457 462 462 ILE ILE M . n 
A 1 458 ALA 458 463 463 ALA ALA M . n 
A 1 459 GLY 459 464 464 GLY GLY M . n 
A 1 460 PHE 460 465 465 PHE PHE M . n 
A 1 461 GLU 461 466 466 GLU GLU M . n 
A 1 462 ILE 462 467 467 ILE ILE M . n 
A 1 463 PHE 463 468 468 PHE PHE M . n 
A 1 464 ASP 464 469 469 ASP ASP M . n 
A 1 465 PHE 465 470 470 PHE PHE M . n 
A 1 466 ASN 466 471 471 ASN ASN M . n 
A 1 467 SER 467 472 472 SER SER M . n 
A 1 468 PHE 468 473 473 PHE PHE M . n 
A 1 469 GLU 469 474 474 GLU GLU M . n 
A 1 470 GLN 470 475 475 GLN GLN M . n 
A 1 471 LEU 471 476 476 LEU LEU M . n 
A 1 472 CYS 472 477 477 CYS CYS M . n 
A 1 473 ILE 473 478 478 ILE ILE M . n 
A 1 474 ASN 474 479 479 ASN ASN M . n 
A 1 475 PHE 475 480 480 PHE PHE M . n 
A 1 476 THR 476 481 481 THR THR M . n 
A 1 477 ASN 477 482 482 ASN ASN M . n 
A 1 478 GLU 478 483 483 GLU GLU M . n 
A 1 479 LYS 479 484 484 LYS LYS M . n 
A 1 480 LEU 480 485 485 LEU LEU M . n 
A 1 481 GLN 481 486 486 GLN GLN M . n 
A 1 482 GLN 482 487 487 GLN GLN M . n 
A 1 483 PHE 483 488 488 PHE PHE M . n 
A 1 484 PHE 484 489 489 PHE PHE M . n 
A 1 485 ASN 485 490 490 ASN ASN M . n 
A 1 486 HIS 486 491 491 HIS HIS M . n 
A 1 487 HIS 487 492 492 HIS HIS M . n 
A 1 488 MET 488 493 493 MET MET M . n 
A 1 489 PHE 489 494 494 PHE PHE M . n 
A 1 490 VAL 490 495 495 VAL VAL M . n 
A 1 491 LEU 491 496 496 LEU LEU M . n 
A 1 492 GLU 492 497 497 GLU GLU M . n 
A 1 493 GLN 493 498 498 GLN GLN M . n 
A 1 494 GLU 494 499 499 GLU GLU M . n 
A 1 495 GLU 495 500 500 GLU GLU M . n 
A 1 496 TYR 496 501 501 TYR TYR M . n 
A 1 497 LYS 497 502 502 LYS LYS M . n 
A 1 498 LYS 498 503 503 LYS LYS M . n 
A 1 499 GLU 499 504 504 GLU GLU M . n 
A 1 500 GLY 500 505 505 GLY GLY M . n 
A 1 501 ILE 501 506 506 ILE ILE M . n 
A 1 502 GLU 502 507 507 GLU GLU M . n 
A 1 503 TRP 503 508 508 TRP TRP M . n 
A 1 504 THR 504 509 509 THR THR M . n 
A 1 505 PHE 505 510 510 PHE PHE M . n 
A 1 506 ILE 506 511 511 ILE ILE M . n 
A 1 507 ASP 507 512 512 ASP ASP M . n 
A 1 508 PHE 508 513 513 PHE PHE M . n 
A 1 509 GLY 509 514 514 GLY GLY M . n 
A 1 510 MET 510 515 515 MET MET M . n 
A 1 511 ASP 511 516 516 ASP ASP M . n 
A 1 512 LEU 512 517 517 LEU LEU M . n 
A 1 513 GLN 513 518 518 GLN GLN M . n 
A 1 514 ALA 514 519 519 ALA ALA M . n 
A 1 515 CYS 515 520 520 CYS CYS M . n 
A 1 516 ILE 516 521 521 ILE ILE M . n 
A 1 517 ASP 517 522 522 ASP ASP M . n 
A 1 518 LEU 518 523 523 LEU LEU M . n 
A 1 519 ILE 519 524 524 ILE ILE M . n 
A 1 520 GLU 520 525 525 GLU GLU M . n 
A 1 521 LYS 521 526 526 LYS LYS M . n 
A 1 522 PRO 522 527 527 PRO PRO M . n 
A 1 523 MET 523 528 528 MET MET M . n 
A 1 524 GLY 524 529 529 GLY GLY M . n 
A 1 525 ILE 525 530 530 ILE ILE M . n 
A 1 526 MET 526 531 531 MET MET M . n 
A 1 527 SER 527 532 532 SER SER M . n 
A 1 528 ILE 528 533 533 ILE ILE M . n 
A 1 529 LEU 529 534 534 LEU LEU M . n 
A 1 530 GLU 530 535 535 GLU GLU M . n 
A 1 531 GLU 531 536 536 GLU GLU M . n 
A 1 532 GLU 532 537 537 GLU GLU M . n 
A 1 533 CYS 533 538 538 CYS CYS M . n 
A 1 534 MET 534 539 539 MET MET M . n 
A 1 535 PHE 535 540 540 PHE PHE M . n 
A 1 536 PRO 536 541 541 PRO PRO M . n 
A 1 537 LYS 537 542 542 LYS LYS M . n 
A 1 538 ALA 538 543 543 ALA ALA M . n 
A 1 539 THR 539 544 544 THR THR M . n 
A 1 540 ASP 540 545 545 ASP ASP M . n 
A 1 541 MET 541 546 546 MET MET M . n 
A 1 542 THR 542 547 547 THR THR M . n 
A 1 543 PHE 543 548 548 PHE PHE M . n 
A 1 544 LYS 544 549 549 LYS LYS M . n 
A 1 545 ALA 545 550 550 ALA ALA M . n 
A 1 546 LYS 546 551 551 LYS LYS M . n 
A 1 547 LEU 547 552 552 LEU LEU M . n 
A 1 548 PHE 548 553 553 PHE PHE M . n 
A 1 549 ASP 549 554 554 ASP ASP M . n 
A 1 550 ASN 550 555 555 ASN ASN M . n 
A 1 551 HIS 551 556 556 HIS HIS M . n 
A 1 552 LEU 552 557 557 LEU LEU M . n 
A 1 553 GLY 553 558 558 GLY GLY M . n 
A 1 554 LYS 554 559 559 LYS LYS M . n 
A 1 555 SER 555 560 560 SER SER M . n 
A 1 556 ALA 556 561 561 ALA ALA M . n 
A 1 557 ASN 557 562 562 ASN ASN M . n 
A 1 558 PHE 558 563 563 PHE PHE M . n 
A 1 559 GLN 559 564 564 GLN GLN M . n 
A 1 560 LYS 560 565 565 LYS LYS M . n 
A 1 561 PRO 561 566 566 PRO PRO M . n 
A 1 562 ARG 562 567 567 ARG ARG M . n 
A 1 563 ASN 563 568 568 ASN ASN M . n 
A 1 564 ILE 564 569 569 ILE ILE M . n 
A 1 565 LYS 565 570 570 LYS LYS M . n 
A 1 566 GLY 566 571 571 GLY GLY M . n 
A 1 567 LYS 567 572 572 LYS LYS M . n 
A 1 568 PRO 568 573 573 PRO PRO M . n 
A 1 569 GLU 569 574 574 GLU GLU M . n 
A 1 570 ALA 570 575 575 ALA ALA M . n 
A 1 571 HIS 571 576 576 HIS HIS M . n 
A 1 572 PHE 572 577 577 PHE PHE M . n 
A 1 573 SER 573 578 578 SER SER M . n 
A 1 574 LEU 574 579 579 LEU LEU M . n 
A 1 575 ILE 575 580 580 ILE ILE M . n 
A 1 576 HIS 576 581 581 HIS HIS M . n 
A 1 577 TYR 577 582 582 TYR TYR M . n 
A 1 578 ALA 578 583 583 ALA ALA M . n 
A 1 579 GLY 579 584 584 GLY GLY M . n 
A 1 580 ILE 580 585 585 ILE ILE M . n 
A 1 581 VAL 581 586 586 VAL VAL M . n 
A 1 582 ASP 582 587 587 ASP ASP M . n 
A 1 583 TYR 583 588 588 TYR TYR M . n 
A 1 584 ASN 584 589 589 ASN ASN M . n 
A 1 585 ILE 585 590 590 ILE ILE M . n 
A 1 586 ILE 586 591 591 ILE ILE M . n 
A 1 587 GLY 587 592 592 GLY GLY M . n 
A 1 588 TRP 588 593 593 TRP TRP M . n 
A 1 589 LEU 589 594 594 LEU LEU M . n 
A 1 590 GLN 590 595 595 GLN GLN M . n 
A 1 591 LYS 591 596 596 LYS LYS M . n 
A 1 592 ASN 592 597 597 ASN ASN M . n 
A 1 593 LYS 593 598 598 LYS LYS M . n 
A 1 594 ASP 594 599 599 ASP ASP M . n 
A 1 595 PRO 595 600 600 PRO PRO M . n 
A 1 596 LEU 596 601 601 LEU LEU M . n 
A 1 597 ASN 597 602 602 ASN ASN M . n 
A 1 598 GLU 598 603 603 GLU GLU M . n 
A 1 599 THR 599 604 604 THR THR M . n 
A 1 600 VAL 600 605 605 VAL VAL M . n 
A 1 601 VAL 601 606 606 VAL VAL M . n 
A 1 602 GLY 602 607 607 GLY GLY M . n 
A 1 603 LEU 603 608 608 LEU LEU M . n 
A 1 604 TYR 604 609 609 TYR TYR M . n 
A 1 605 GLN 605 610 610 GLN GLN M . n 
A 1 606 LYS 606 611 611 LYS LYS M . n 
A 1 607 SER 607 612 612 SER SER M . n 
A 1 608 SER 608 613 613 SER SER M . n 
A 1 609 LEU 609 614 614 LEU LEU M . n 
A 1 610 LYS 610 615 615 LYS LYS M . n 
A 1 611 LEU 611 616 616 LEU LEU M . n 
A 1 612 LEU 612 617 617 LEU LEU M . n 
A 1 613 SER 613 618 618 SER SER M . n 
A 1 614 THR 614 619 619 THR THR M . n 
A 1 615 LEU 615 620 620 LEU LEU M . n 
A 1 616 PHE 616 621 621 PHE PHE M . n 
A 1 617 ALA 617 622 622 ALA ALA M . n 
A 1 618 ASN 618 623 623 ASN ASN M . n 
A 1 619 TYR 619 624 624 TYR TYR M . n 
A 1 620 ALA 620 625 ?   ?   ?   M . n 
A 1 621 GLY 621 626 ?   ?   ?   M . n 
A 1 622 ALA 622 627 ?   ?   ?   M . n 
A 1 623 ASP 623 628 ?   ?   ?   M . n 
A 1 624 ALA 624 629 ?   ?   ?   M . n 
A 1 625 PRO 625 630 ?   ?   ?   M . n 
A 1 626 ILE 626 631 ?   ?   ?   M . n 
A 1 627 GLU 627 632 ?   ?   ?   M . n 
A 1 628 LYS 628 633 ?   ?   ?   M . n 
A 1 629 GLY 629 634 634 GLY GLY M . n 
A 1 630 LYS 630 635 635 LYS LYS M . n 
A 1 631 GLY 631 636 636 GLY GLY M . n 
A 1 632 LYS 632 637 637 LYS LYS M . n 
A 1 633 ALA 633 638 638 ALA ALA M . n 
A 1 634 LYS 634 639 639 LYS LYS M . n 
A 1 635 LYS 635 640 640 LYS LYS M . n 
A 1 636 GLY 636 641 641 GLY GLY M . n 
A 1 637 SER 637 642 642 SER SER M . n 
A 1 638 SER 638 643 643 SER SER M . n 
A 1 639 PHE 639 644 644 PHE PHE M . n 
A 1 640 GLN 640 645 645 GLN GLN M . n 
A 1 641 THR 641 646 646 THR THR M . n 
A 1 642 VAL 642 647 647 VAL VAL M . n 
A 1 643 SER 643 648 648 SER SER M . n 
A 1 644 ALA 644 649 649 ALA ALA M . n 
A 1 645 LEU 645 650 650 LEU LEU M . n 
A 1 646 HIS 646 651 651 HIS HIS M . n 
A 1 647 ARG 647 652 652 ARG ARG M . n 
A 1 648 GLU 648 653 653 GLU GLU M . n 
A 1 649 ASN 649 654 654 ASN ASN M . n 
A 1 650 LEU 650 655 655 LEU LEU M . n 
A 1 651 ASN 651 656 656 ASN ASN M . n 
A 1 652 LYS 652 657 657 LYS LYS M . n 
A 1 653 LEU 653 658 658 LEU LEU M . n 
A 1 654 MET 654 659 659 MET MET M . n 
A 1 655 THR 655 660 660 THR THR M . n 
A 1 656 ASN 656 661 661 ASN ASN M . n 
A 1 657 LEU 657 662 662 LEU LEU M . n 
A 1 658 ARG 658 663 663 ARG ARG M . n 
A 1 659 SER 659 664 664 SER SER M . n 
A 1 660 THR 660 665 665 THR THR M . n 
A 1 661 HIS 661 666 666 HIS HIS M . n 
A 1 662 PRO 662 667 667 PRO PRO M . n 
A 1 663 HIS 663 668 668 HIS HIS M . n 
A 1 664 PHE 664 669 669 PHE PHE M . n 
A 1 665 VAL 665 670 670 VAL VAL M . n 
A 1 666 ARG 666 671 671 ARG ARG M . n 
A 1 667 CYS 667 672 672 CYS CYS M . n 
A 1 668 ILE 668 673 673 ILE ILE M . n 
A 1 669 ILE 669 674 674 ILE ILE M . n 
A 1 670 PRO 670 675 675 PRO PRO M . n 
A 1 671 ASN 671 676 676 ASN ASN M . n 
A 1 672 GLU 672 677 677 GLU GLU M . n 
A 1 673 THR 673 678 678 THR THR M . n 
A 1 674 LYS 674 679 679 LYS LYS M . n 
A 1 675 SER 675 680 680 SER SER M . n 
A 1 676 PRO 676 681 681 PRO PRO M . n 
A 1 677 GLY 677 682 682 GLY GLY M . n 
A 1 678 VAL 678 683 683 VAL VAL M . n 
A 1 679 MET 679 684 684 MET MET M . n 
A 1 680 ASP 680 685 685 ASP ASP M . n 
A 1 681 ASN 681 686 686 ASN ASN M . n 
A 1 682 PRO 682 687 687 PRO PRO M . n 
A 1 683 LEU 683 688 688 LEU LEU M . n 
A 1 684 VAL 684 689 689 VAL VAL M . n 
A 1 685 MET 685 690 690 MET MET M . n 
A 1 686 HIS 686 691 691 HIS HIS M . n 
A 1 687 GLN 687 692 692 GLN GLN M . n 
A 1 688 LEU 688 693 693 LEU LEU M . n 
A 1 689 ARG 689 694 694 ARG ARG M . n 
A 1 690 CYS 690 695 695 CYS CYS M . n 
A 1 691 ASN 691 696 696 ASN ASN M . n 
A 1 692 GLY 692 697 697 GLY GLY M . n 
A 1 693 VAL 693 698 698 VAL VAL M . n 
A 1 694 LEU 694 699 699 LEU LEU M . n 
A 1 695 GLU 695 700 700 GLU GLU M . n 
A 1 696 GLY 696 701 701 GLY GLY M . n 
A 1 697 ILE 697 702 702 ILE ILE M . n 
A 1 698 ARG 698 703 703 ARG ARG M . n 
A 1 699 ILE 699 704 704 ILE ILE M . n 
A 1 700 CYS 700 705 705 CYS CYS M . n 
A 1 701 ARG 701 706 706 ARG ARG M . n 
A 1 702 LYS 702 707 707 LYS LYS M . n 
A 1 703 GLY 703 708 708 GLY GLY M . n 
A 1 704 PHE 704 709 709 PHE PHE M . n 
A 1 705 PRO 705 710 710 PRO PRO M . n 
A 1 706 ASN 706 711 711 ASN ASN M . n 
A 1 707 ARG 707 712 712 ARG ARG M . n 
A 1 708 ILE 708 713 713 ILE ILE M . n 
A 1 709 LEU 709 714 714 LEU LEU M . n 
A 1 710 TYR 710 715 715 TYR TYR M . n 
A 1 711 GLY 711 716 716 GLY GLY M . n 
A 1 712 ASP 712 717 717 ASP ASP M . n 
A 1 713 PHE 713 718 718 PHE PHE M . n 
A 1 714 ARG 714 719 719 ARG ARG M . n 
A 1 715 GLN 715 720 720 GLN GLN M . n 
A 1 716 ARG 716 721 721 ARG ARG M . n 
A 1 717 TYR 717 722 722 TYR TYR M . n 
A 1 718 ARG 718 723 723 ARG ARG M . n 
A 1 719 ILE 719 724 724 ILE ILE M . n 
A 1 720 LEU 720 725 725 LEU LEU M . n 
A 1 721 ASN 721 726 726 ASN ASN M . n 
A 1 722 PRO 722 727 727 PRO PRO M . n 
A 1 723 ALA 723 728 728 ALA ALA M . n 
A 1 724 ALA 724 729 ?   ?   ?   M . n 
A 1 725 ILE 725 730 ?   ?   ?   M . n 
A 1 726 PRO 726 731 ?   ?   ?   M . n 
A 1 727 GLU 727 732 ?   ?   ?   M . n 
A 1 728 GLY 728 733 ?   ?   ?   M . n 
A 1 729 GLN 729 734 ?   ?   ?   M . n 
A 1 730 PHE 730 735 ?   ?   ?   M . n 
A 1 731 ILE 731 736 ?   ?   ?   M . n 
A 1 732 ASP 732 737 ?   ?   ?   M . n 
A 1 733 SER 733 738 738 SER SER M . n 
A 1 734 ARG 734 739 739 ARG ARG M . n 
A 1 735 LYS 735 740 740 LYS LYS M . n 
A 1 736 GLY 736 741 741 GLY GLY M . n 
A 1 737 ALA 737 742 742 ALA ALA M . n 
A 1 738 GLU 738 743 743 GLU GLU M . n 
A 1 739 LYS 739 744 744 LYS LYS M . n 
A 1 740 LEU 740 745 745 LEU LEU M . n 
A 1 741 LEU 741 746 746 LEU LEU M . n 
A 1 742 SER 742 747 747 SER SER M . n 
A 1 743 SER 743 748 748 SER SER M . n 
A 1 744 LEU 744 749 749 LEU LEU M . n 
A 1 745 ASP 745 750 750 ASP ASP M . n 
A 1 746 ILE 746 751 751 ILE ILE M . n 
A 1 747 ASP 747 752 752 ASP ASP M . n 
A 1 748 HIS 748 753 753 HIS HIS M . n 
A 1 749 ASN 749 754 754 ASN ASN M . n 
A 1 750 GLN 750 755 755 GLN GLN M . n 
A 1 751 TYR 751 756 756 TYR TYR M . n 
A 1 752 LYS 752 757 757 LYS LYS M . n 
A 1 753 PHE 753 758 758 PHE PHE M . n 
A 1 754 GLY 754 759 759 GLY GLY M . n 
A 1 755 HIS 755 760 760 HIS HIS M . n 
A 1 756 THR 756 761 761 THR THR M . n 
A 1 757 LYS 757 762 762 LYS LYS M . n 
A 1 758 VAL 758 763 763 VAL VAL M . n 
A 1 759 PHE 759 764 764 PHE PHE M . n 
A 1 760 PHE 760 765 765 PHE PHE M . n 
A 1 761 LYS 761 766 766 LYS LYS M . n 
A 1 762 ALA 762 767 767 ALA ALA M . n 
A 1 763 GLY 763 768 768 GLY GLY M . n 
A 1 764 LEU 764 769 769 LEU LEU M . n 
A 1 765 LEU 765 770 770 LEU LEU M . n 
A 1 766 GLY 766 771 771 GLY GLY M . n 
A 1 767 LEU 767 772 772 LEU LEU M . n 
A 1 768 LEU 768 773 773 LEU LEU M . n 
A 1 769 GLU 769 774 774 GLU GLU M . n 
A 1 770 GLU 770 775 775 GLU GLU M . n 
A 1 771 MET 771 776 776 MET MET M . n 
A 1 772 ARG 772 777 777 ARG ARG M . n 
A 1 773 ASP 773 778 778 ASP ASP M . n 
A 1 774 GLU 774 779 779 GLU GLU M . n 
A 1 775 ARG 775 780 780 ARG ARG M . n 
A 1 776 LEU 776 781 781 LEU LEU M . n 
B 2 1   THR 1   5   5   THR THR F . n 
B 2 2   THR 2   6   6   THR THR F . n 
B 2 3   ALA 3   7   7   ALA ALA F . n 
B 2 4   LEU 4   8   8   LEU LEU F . n 
B 2 5   VAL 5   9   9   VAL VAL F . n 
B 2 6   CYS 6   10  10  CYS CYS F . n 
B 2 7   ASP 7   11  11  ASP ASP F . n 
B 2 8   ASN 8   12  12  ASN ASN F . n 
B 2 9   GLY 9   13  13  GLY GLY F . n 
B 2 10  SER 10  14  14  SER SER F . n 
B 2 11  GLY 11  15  15  GLY GLY F . n 
B 2 12  LEU 12  16  16  LEU LEU F . n 
B 2 13  VAL 13  17  17  VAL VAL F . n 
B 2 14  LYS 14  18  18  LYS LYS F . n 
B 2 15  ALA 15  19  19  ALA ALA F . n 
B 2 16  GLY 16  20  20  GLY GLY F . n 
B 2 17  PHE 17  21  21  PHE PHE F . n 
B 2 18  ALA 18  22  22  ALA ALA F . n 
B 2 19  GLY 19  23  23  GLY GLY F . n 
B 2 20  ASP 20  24  24  ASP ASP F . n 
B 2 21  ASP 21  25  25  ASP ASP F . n 
B 2 22  ALA 22  26  26  ALA ALA F . n 
B 2 23  PRO 23  27  27  PRO PRO F . n 
B 2 24  ARG 24  28  28  ARG ARG F . n 
B 2 25  ALA 25  29  29  ALA ALA F . n 
B 2 26  VAL 26  30  30  VAL VAL F . n 
B 2 27  PHE 27  31  31  PHE PHE F . n 
B 2 28  PRO 28  32  32  PRO PRO F . n 
B 2 29  SER 29  33  33  SER SER F . n 
B 2 30  ILE 30  34  34  ILE ILE F . n 
B 2 31  VAL 31  35  35  VAL VAL F . n 
B 2 32  GLY 32  36  36  GLY GLY F . n 
B 2 33  ARG 33  37  37  ARG ARG F . n 
B 2 34  PRO 34  38  38  PRO PRO F . n 
B 2 35  ARG 35  39  39  ARG ARG F . n 
B 2 36  HIS 36  40  40  HIS HIS F . n 
B 2 37  GLN 37  41  41  GLN GLN F . n 
B 2 38  GLY 38  42  42  GLY GLY F . n 
B 2 39  VAL 39  43  43  VAL VAL F . n 
B 2 40  MET 40  44  44  MET MET F . n 
B 2 41  VAL 41  45  45  VAL VAL F . n 
B 2 42  GLY 42  46  46  GLY GLY F . n 
B 2 43  MET 43  47  47  MET MET F . n 
B 2 44  GLY 44  48  48  GLY GLY F . n 
B 2 45  GLN 45  49  49  GLN GLN F . n 
B 2 46  LYS 46  50  50  LYS LYS F . n 
B 2 47  ASP 47  51  51  ASP ASP F . n 
B 2 48  SER 48  52  52  SER SER F . n 
B 2 49  TYR 49  53  53  TYR TYR F . n 
B 2 50  VAL 50  54  54  VAL VAL F . n 
B 2 51  GLY 51  55  55  GLY GLY F . n 
B 2 52  ASP 52  56  56  ASP ASP F . n 
B 2 53  GLU 53  57  57  GLU GLU F . n 
B 2 54  ALA 54  58  58  ALA ALA F . n 
B 2 55  GLN 55  59  59  GLN GLN F . n 
B 2 56  SER 56  60  60  SER SER F . n 
B 2 57  LYS 57  61  61  LYS LYS F . n 
B 2 58  ARG 58  62  62  ARG ARG F . n 
B 2 59  GLY 59  63  63  GLY GLY F . n 
B 2 60  ILE 60  64  64  ILE ILE F . n 
B 2 61  LEU 61  65  65  LEU LEU F . n 
B 2 62  THR 62  66  66  THR THR F . n 
B 2 63  LEU 63  67  67  LEU LEU F . n 
B 2 64  LYS 64  68  68  LYS LYS F . n 
B 2 65  TYR 65  69  69  TYR TYR F . n 
B 2 66  PRO 66  70  70  PRO PRO F . n 
B 2 67  ILE 67  71  71  ILE ILE F . n 
B 2 68  GLU 68  72  72  GLU GLU F . n 
B 2 69  HIS 69  73  73  HIS HIS F . n 
B 2 70  GLY 70  74  74  GLY GLY F . n 
B 2 71  ILE 71  75  75  ILE ILE F . n 
B 2 72  ILE 72  76  76  ILE ILE F . n 
B 2 73  THR 73  77  77  THR THR F . n 
B 2 74  ASN 74  78  78  ASN ASN F . n 
B 2 75  TRP 75  79  79  TRP TRP F . n 
B 2 76  ASP 76  80  80  ASP ASP F . n 
B 2 77  ASP 77  81  81  ASP ASP F . n 
B 2 78  MET 78  82  82  MET MET F . n 
B 2 79  GLU 79  83  83  GLU GLU F . n 
B 2 80  LYS 80  84  84  LYS LYS F . n 
B 2 81  ILE 81  85  85  ILE ILE F . n 
B 2 82  TRP 82  86  86  TRP TRP F . n 
B 2 83  HIS 83  87  87  HIS HIS F . n 
B 2 84  HIS 84  88  88  HIS HIS F . n 
B 2 85  THR 85  89  89  THR THR F . n 
B 2 86  PHE 86  90  90  PHE PHE F . n 
B 2 87  TYR 87  91  91  TYR TYR F . n 
B 2 88  ASN 88  92  92  ASN ASN F . n 
B 2 89  GLU 89  93  93  GLU GLU F . n 
B 2 90  LEU 90  94  94  LEU LEU F . n 
B 2 91  ARG 91  95  95  ARG ARG F . n 
B 2 92  VAL 92  96  96  VAL VAL F . n 
B 2 93  ALA 93  97  97  ALA ALA F . n 
B 2 94  PRO 94  98  98  PRO PRO F . n 
B 2 95  GLU 95  99  99  GLU GLU F . n 
B 2 96  GLU 96  100 100 GLU GLU F . n 
B 2 97  HIS 97  101 101 HIS HIS F . n 
B 2 98  PRO 98  102 102 PRO PRO F . n 
B 2 99  THR 99  103 103 THR THR F . n 
B 2 100 LEU 100 104 104 LEU LEU F . n 
B 2 101 LEU 101 105 105 LEU LEU F . n 
B 2 102 THR 102 106 106 THR THR F . n 
B 2 103 GLU 103 107 107 GLU GLU F . n 
B 2 104 ALA 104 108 108 ALA ALA F . n 
B 2 105 PRO 105 109 109 PRO PRO F . n 
B 2 106 LEU 106 110 110 LEU LEU F . n 
B 2 107 ASN 107 111 111 ASN ASN F . n 
B 2 108 PRO 108 112 112 PRO PRO F . n 
B 2 109 LYS 109 113 113 LYS LYS F . n 
B 2 110 ALA 110 114 114 ALA ALA F . n 
B 2 111 ASN 111 115 115 ASN ASN F . n 
B 2 112 ARG 112 116 116 ARG ARG F . n 
B 2 113 GLU 113 117 117 GLU GLU F . n 
B 2 114 LYS 114 118 118 LYS LYS F . n 
B 2 115 MET 115 119 119 MET MET F . n 
B 2 116 THR 116 120 120 THR THR F . n 
B 2 117 GLN 117 121 121 GLN GLN F . n 
B 2 118 ILE 118 122 122 ILE ILE F . n 
B 2 119 MET 119 123 123 MET MET F . n 
B 2 120 PHE 120 124 124 PHE PHE F . n 
B 2 121 GLU 121 125 125 GLU GLU F . n 
B 2 122 THR 122 126 126 THR THR F . n 
B 2 123 PHE 123 127 127 PHE PHE F . n 
B 2 124 ASN 124 128 128 ASN ASN F . n 
B 2 125 VAL 125 129 129 VAL VAL F . n 
B 2 126 PRO 126 130 130 PRO PRO F . n 
B 2 127 ALA 127 131 131 ALA ALA F . n 
B 2 128 MET 128 132 132 MET MET F . n 
B 2 129 TYR 129 133 133 TYR TYR F . n 
B 2 130 VAL 130 134 134 VAL VAL F . n 
B 2 131 ALA 131 135 135 ALA ALA F . n 
B 2 132 ILE 132 136 136 ILE ILE F . n 
B 2 133 GLN 133 137 137 GLN GLN F . n 
B 2 134 ALA 134 138 138 ALA ALA F . n 
B 2 135 VAL 135 139 139 VAL VAL F . n 
B 2 136 LEU 136 140 140 LEU LEU F . n 
B 2 137 SER 137 141 141 SER SER F . n 
B 2 138 LEU 138 142 142 LEU LEU F . n 
B 2 139 TYR 139 143 143 TYR TYR F . n 
B 2 140 ALA 140 144 144 ALA ALA F . n 
B 2 141 SER 141 145 145 SER SER F . n 
B 2 142 GLY 142 146 146 GLY GLY F . n 
B 2 143 ARG 143 147 147 ARG ARG F . n 
B 2 144 THR 144 148 148 THR THR F . n 
B 2 145 THR 145 149 149 THR THR F . n 
B 2 146 GLY 146 150 150 GLY GLY F . n 
B 2 147 ILE 147 151 151 ILE ILE F . n 
B 2 148 VAL 148 152 152 VAL VAL F . n 
B 2 149 LEU 149 153 153 LEU LEU F . n 
B 2 150 ASP 150 154 154 ASP ASP F . n 
B 2 151 SER 151 155 155 SER SER F . n 
B 2 152 GLY 152 156 156 GLY GLY F . n 
B 2 153 ASP 153 157 157 ASP ASP F . n 
B 2 154 GLY 154 158 158 GLY GLY F . n 
B 2 155 VAL 155 159 159 VAL VAL F . n 
B 2 156 THR 156 160 160 THR THR F . n 
B 2 157 HIS 157 161 161 HIS HIS F . n 
B 2 158 ASN 158 162 162 ASN ASN F . n 
B 2 159 VAL 159 163 163 VAL VAL F . n 
B 2 160 PRO 160 164 164 PRO PRO F . n 
B 2 161 ILE 161 165 165 ILE ILE F . n 
B 2 162 TYR 162 166 166 TYR TYR F . n 
B 2 163 GLU 163 167 167 GLU GLU F . n 
B 2 164 GLY 164 168 168 GLY GLY F . n 
B 2 165 TYR 165 169 169 TYR TYR F . n 
B 2 166 ALA 166 170 170 ALA ALA F . n 
B 2 167 LEU 167 171 171 LEU LEU F . n 
B 2 168 PRO 168 172 172 PRO PRO F . n 
B 2 169 HIS 169 173 173 HIS HIS F . n 
B 2 170 ALA 170 174 174 ALA ALA F . n 
B 2 171 ILE 171 175 175 ILE ILE F . n 
B 2 172 MET 172 176 176 MET MET F . n 
B 2 173 ARG 173 177 177 ARG ARG F . n 
B 2 174 LEU 174 178 178 LEU LEU F . n 
B 2 175 ASP 175 179 179 ASP ASP F . n 
B 2 176 LEU 176 180 180 LEU LEU F . n 
B 2 177 ALA 177 181 181 ALA ALA F . n 
B 2 178 GLY 178 182 182 GLY GLY F . n 
B 2 179 ARG 179 183 183 ARG ARG F . n 
B 2 180 ASP 180 184 184 ASP ASP F . n 
B 2 181 LEU 181 185 185 LEU LEU F . n 
B 2 182 THR 182 186 186 THR THR F . n 
B 2 183 ASP 183 187 187 ASP ASP F . n 
B 2 184 TYR 184 188 188 TYR TYR F . n 
B 2 185 LEU 185 189 189 LEU LEU F . n 
B 2 186 MET 186 190 190 MET MET F . n 
B 2 187 LYS 187 191 191 LYS LYS F . n 
B 2 188 ILE 188 192 192 ILE ILE F . n 
B 2 189 LEU 189 193 193 LEU LEU F . n 
B 2 190 THR 190 194 194 THR THR F . n 
B 2 191 GLU 191 195 195 GLU GLU F . n 
B 2 192 ARG 192 196 196 ARG ARG F . n 
B 2 193 GLY 193 197 197 GLY GLY F . n 
B 2 194 TYR 194 198 198 TYR TYR F . n 
B 2 195 SER 195 199 199 SER SER F . n 
B 2 196 PHE 196 200 200 PHE PHE F . n 
B 2 197 VAL 197 201 201 VAL VAL F . n 
B 2 198 THR 198 202 202 THR THR F . n 
B 2 199 THR 199 203 203 THR THR F . n 
B 2 200 ALA 200 204 204 ALA ALA F . n 
B 2 201 GLU 201 205 205 GLU GLU F . n 
B 2 202 ARG 202 206 206 ARG ARG F . n 
B 2 203 GLU 203 207 207 GLU GLU F . n 
B 2 204 ILE 204 208 208 ILE ILE F . n 
B 2 205 VAL 205 209 209 VAL VAL F . n 
B 2 206 ARG 206 210 210 ARG ARG F . n 
B 2 207 ASP 207 211 211 ASP ASP F . n 
B 2 208 ILE 208 212 212 ILE ILE F . n 
B 2 209 LYS 209 213 213 LYS LYS F . n 
B 2 210 GLU 210 214 214 GLU GLU F . n 
B 2 211 LYS 211 215 215 LYS LYS F . n 
B 2 212 LEU 212 216 216 LEU LEU F . n 
B 2 213 CYS 213 217 217 CYS CYS F . n 
B 2 214 TYR 214 218 218 TYR TYR F . n 
B 2 215 VAL 215 219 219 VAL VAL F . n 
B 2 216 ALA 216 220 220 ALA ALA F . n 
B 2 217 LEU 217 221 221 LEU LEU F . n 
B 2 218 ASP 218 222 222 ASP ASP F . n 
B 2 219 PHE 219 223 223 PHE PHE F . n 
B 2 220 GLU 220 224 224 GLU GLU F . n 
B 2 221 ASN 221 225 225 ASN ASN F . n 
B 2 222 GLU 222 226 226 GLU GLU F . n 
B 2 223 MET 223 227 227 MET MET F . n 
B 2 224 ALA 224 228 228 ALA ALA F . n 
B 2 225 THR 225 229 229 THR THR F . n 
B 2 226 ALA 226 230 230 ALA ALA F . n 
B 2 227 ALA 227 231 231 ALA ALA F . n 
B 2 228 SER 228 232 232 SER SER F . n 
B 2 229 SER 229 233 233 SER SER F . n 
B 2 230 SER 230 234 234 SER SER F . n 
B 2 231 SER 231 235 235 SER SER F . n 
B 2 232 LEU 232 236 236 LEU LEU F . n 
B 2 233 GLU 233 237 237 GLU GLU F . n 
B 2 234 LYS 234 238 238 LYS LYS F . n 
B 2 235 SER 235 239 239 SER SER F . n 
B 2 236 TYR 236 240 240 TYR TYR F . n 
B 2 237 GLU 237 241 241 GLU GLU F . n 
B 2 238 LEU 238 242 242 LEU LEU F . n 
B 2 239 PRO 239 243 243 PRO PRO F . n 
B 2 240 ASP 240 244 244 ASP ASP F . n 
B 2 241 GLY 241 245 245 GLY GLY F . n 
B 2 242 GLN 242 246 246 GLN GLN F . n 
B 2 243 VAL 243 247 247 VAL VAL F . n 
B 2 244 ILE 244 248 248 ILE ILE F . n 
B 2 245 THR 245 249 249 THR THR F . n 
B 2 246 ILE 246 250 250 ILE ILE F . n 
B 2 247 GLY 247 251 251 GLY GLY F . n 
B 2 248 ASN 248 252 252 ASN ASN F . n 
B 2 249 GLU 249 253 253 GLU GLU F . n 
B 2 250 ARG 250 254 254 ARG ARG F . n 
B 2 251 PHE 251 255 255 PHE PHE F . n 
B 2 252 ARG 252 256 256 ARG ARG F . n 
B 2 253 CYS 253 257 257 CYS CYS F . n 
B 2 254 PRO 254 258 258 PRO PRO F . n 
B 2 255 GLU 255 259 259 GLU GLU F . n 
B 2 256 THR 256 260 260 THR THR F . n 
B 2 257 LEU 257 261 261 LEU LEU F . n 
B 2 258 PHE 258 262 262 PHE PHE F . n 
B 2 259 GLN 259 263 263 GLN GLN F . n 
B 2 260 PRO 260 264 264 PRO PRO F . n 
B 2 261 SER 261 265 265 SER SER F . n 
B 2 262 PHE 262 266 266 PHE PHE F . n 
B 2 263 ILE 263 267 267 ILE ILE F . n 
B 2 264 GLY 264 268 268 GLY GLY F . n 
B 2 265 MET 265 269 269 MET MET F . n 
B 2 266 GLU 266 270 270 GLU GLU F . n 
B 2 267 SER 267 271 271 SER SER F . n 
B 2 268 ALA 268 272 272 ALA ALA F . n 
B 2 269 GLY 269 273 273 GLY GLY F . n 
B 2 270 ILE 270 274 274 ILE ILE F . n 
B 2 271 HIS 271 275 275 HIS HIS F . n 
B 2 272 GLU 272 276 276 GLU GLU F . n 
B 2 273 THR 273 277 277 THR THR F . n 
B 2 274 THR 274 278 278 THR THR F . n 
B 2 275 TYR 275 279 279 TYR TYR F . n 
B 2 276 ASN 276 280 280 ASN ASN F . n 
B 2 277 SER 277 281 281 SER SER F . n 
B 2 278 ILE 278 282 282 ILE ILE F . n 
B 2 279 MET 279 283 283 MET MET F . n 
B 2 280 LYS 280 284 284 LYS LYS F . n 
B 2 281 CYS 281 285 285 CYS CYS F . n 
B 2 282 ASP 282 286 286 ASP ASP F . n 
B 2 283 ILE 283 287 287 ILE ILE F . n 
B 2 284 ASP 284 288 288 ASP ASP F . n 
B 2 285 ILE 285 289 289 ILE ILE F . n 
B 2 286 ARG 286 290 290 ARG ARG F . n 
B 2 287 LYS 287 291 291 LYS LYS F . n 
B 2 288 ASP 288 292 292 ASP ASP F . n 
B 2 289 LEU 289 293 293 LEU LEU F . n 
B 2 290 TYR 290 294 294 TYR TYR F . n 
B 2 291 ALA 291 295 295 ALA ALA F . n 
B 2 292 ASN 292 296 296 ASN ASN F . n 
B 2 293 ASN 293 297 297 ASN ASN F . n 
B 2 294 VAL 294 298 298 VAL VAL F . n 
B 2 295 LEU 295 299 299 LEU LEU F . n 
B 2 296 SER 296 300 300 SER SER F . n 
B 2 297 GLY 297 301 301 GLY GLY F . n 
B 2 298 GLY 298 302 302 GLY GLY F . n 
B 2 299 THR 299 303 303 THR THR F . n 
B 2 300 THR 300 304 304 THR THR F . n 
B 2 301 MET 301 305 305 MET MET F . n 
B 2 302 TYR 302 306 306 TYR TYR F . n 
B 2 303 PRO 303 307 307 PRO PRO F . n 
B 2 304 GLY 304 308 308 GLY GLY F . n 
B 2 305 ILE 305 309 309 ILE ILE F . n 
B 2 306 ALA 306 310 310 ALA ALA F . n 
B 2 307 ASP 307 311 311 ASP ASP F . n 
B 2 308 ARG 308 312 312 ARG ARG F . n 
B 2 309 MET 309 313 313 MET MET F . n 
B 2 310 GLN 310 314 314 GLN GLN F . n 
B 2 311 LYS 311 315 315 LYS LYS F . n 
B 2 312 GLU 312 316 316 GLU GLU F . n 
B 2 313 ILE 313 317 317 ILE ILE F . n 
B 2 314 THR 314 318 318 THR THR F . n 
B 2 315 ALA 315 319 319 ALA ALA F . n 
B 2 316 LEU 316 320 320 LEU LEU F . n 
B 2 317 ALA 317 321 321 ALA ALA F . n 
B 2 318 PRO 318 322 322 PRO PRO F . n 
B 2 319 SER 319 323 323 SER SER F . n 
B 2 320 THR 320 324 324 THR THR F . n 
B 2 321 MET 321 325 325 MET MET F . n 
B 2 322 LYS 322 326 326 LYS LYS F . n 
B 2 323 ILE 323 327 327 ILE ILE F . n 
B 2 324 LYS 324 328 328 LYS LYS F . n 
B 2 325 ILE 325 329 329 ILE ILE F . n 
B 2 326 ILE 326 330 330 ILE ILE F . n 
B 2 327 ALA 327 331 331 ALA ALA F . n 
B 2 328 PRO 328 332 332 PRO PRO F . n 
B 2 329 PRO 329 333 333 PRO PRO F . n 
B 2 330 GLU 330 334 334 GLU GLU F . n 
B 2 331 ARG 331 335 335 ARG ARG F . n 
B 2 332 LYS 332 336 336 LYS LYS F . n 
B 2 333 TYR 333 337 337 TYR TYR F . n 
B 2 334 SER 334 338 338 SER SER F . n 
B 2 335 VAL 335 339 339 VAL VAL F . n 
B 2 336 TRP 336 340 340 TRP TRP F . n 
B 2 337 ILE 337 341 341 ILE ILE F . n 
B 2 338 GLY 338 342 342 GLY GLY F . n 
B 2 339 GLY 339 343 343 GLY GLY F . n 
B 2 340 SER 340 344 344 SER SER F . n 
B 2 341 ILE 341 345 345 ILE ILE F . n 
B 2 342 LEU 342 346 346 LEU LEU F . n 
B 2 343 ALA 343 347 347 ALA ALA F . n 
B 2 344 SER 344 348 348 SER SER F . n 
B 2 345 LEU 345 349 349 LEU LEU F . n 
B 2 346 SER 346 350 350 SER SER F . n 
B 2 347 THR 347 351 351 THR THR F . n 
B 2 348 PHE 348 352 352 PHE PHE F . n 
B 2 349 GLN 349 353 353 GLN GLN F . n 
B 2 350 GLN 350 354 354 GLN GLN F . n 
B 2 351 MET 351 355 355 MET MET F . n 
B 2 352 TRP 352 356 356 TRP TRP F . n 
B 2 353 ILE 353 357 357 ILE ILE F . n 
B 2 354 SER 354 358 358 SER SER F . n 
B 2 355 LYS 355 359 359 LYS LYS F . n 
B 2 356 GLN 356 360 360 GLN GLN F . n 
B 2 357 GLU 357 361 361 GLU GLU F . n 
B 2 358 TYR 358 362 362 TYR TYR F . n 
B 2 359 ASP 359 363 363 ASP ASP F . n 
B 2 360 GLU 360 364 364 GLU GLU F . n 
B 2 361 ALA 361 365 365 ALA ALA F . n 
B 2 362 GLY 362 366 366 GLY GLY F . n 
B 2 363 PRO 363 367 367 PRO PRO F . n 
B 2 364 SER 364 368 368 SER SER F . n 
B 2 365 ILE 365 369 369 ILE ILE F . n 
B 2 366 VAL 366 370 370 VAL VAL F . n 
B 2 367 HIS 367 371 371 HIS HIS F . n 
B 2 368 ARG 368 372 372 ARG ARG F . n 
B 2 369 LYS 369 373 373 LYS LYS F . n 
B 2 370 CYS 370 374 374 CYS CYS F . n 
B 2 371 PHE 371 375 375 PHE PHE F . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ADP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ADP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         C 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          ADP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      ADP 
_pdbx_nonpoly_scheme.auth_mon_id     ADP 
_pdbx_nonpoly_scheme.pdb_strand_id   F 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ZI9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ZI9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ZI9 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ZI9 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.008  ? 9091  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.703  ? 12275 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 13.866 ? 5489  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.049  ? 1338  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1580  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ZI9 
_struct.title                        'Human left ventricle actin and myosin complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ZI9 
_struct_keywords.text            'protein binding, actin, myosin' 
_struct_keywords.pdbx_keywords   'PROTEIN BINDING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP MYH7_HUMAN P12883 ? 1 
;MAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFD
KIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYM
LTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFG
KFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDD
AEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVK
VGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKL
QQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQK
PRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQ
TVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL
NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL
;
6 
2 UNP ACTC_HUMAN P68032 ? 2 
;TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEK
IWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVP
IYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPD
GQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPST
MKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
;
7 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ZI9 M 1 ? 776 ? P12883 6 ? 781 ? 6 781 
2 2 8ZI9 F 1 ? 371 ? P68032 7 ? 377 ? 5 375 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 7   ? ARG A 12  ? ALA M 12  ARG M 17  1 ? 6  
HELX_P HELX_P2  AA2 SER A 14  ? THR A 23  ? SER M 19  THR M 28  1 ? 10 
HELX_P HELX_P3  AA3 PRO A 76  ? ASP A 80  ? PRO M 81  ASP M 85  5 ? 5  
HELX_P HELX_P4  AA4 ASP A 84  ? LEU A 88  ? ASP M 89  LEU M 93  5 ? 5  
HELX_P HELX_P5  AA5 HIS A 92  ? SER A 106 ? HIS M 97  SER M 111 1 ? 15 
HELX_P HELX_P6  AA6 LEU A 126 ? TYR A 129 ? LEU M 131 TYR M 134 5 ? 4  
HELX_P HELX_P7  AA7 THR A 130 ? ARG A 138 ? THR M 135 ARG M 143 1 ? 9  
HELX_P HELX_P8  AA8 HIS A 148 ? ARG A 164 ? HIS M 153 ARG M 169 1 ? 17 
HELX_P HELX_P9  AA9 GLY A 178 ? ALA A 194 ? GLY M 183 ALA M 199 1 ? 17 
HELX_P HELX_P10 AB1 GLU A 212 ? GLY A 226 ? GLU M 217 GLY M 231 1 ? 15 
HELX_P HELX_P11 AB2 LYS A 265 ? ILE A 269 ? LYS M 270 ILE M 274 5 ? 5  
HELX_P HELX_P12 AB3 TYR A 278 ? SER A 286 ? TYR M 283 SER M 291 1 ? 9  
HELX_P HELX_P13 AB4 LYS A 289 ? LEU A 297 ? LYS M 294 LEU M 302 1 ? 9  
HELX_P HELX_P14 AB5 ASN A 301 ? ASP A 304 ? ASN M 306 ASP M 309 5 ? 4  
HELX_P HELX_P15 AB6 TYR A 305 ? GLN A 310 ? TYR M 310 GLN M 315 1 ? 6  
HELX_P HELX_P16 AB7 ASP A 319 ? VAL A 333 ? ASP M 324 VAL M 338 1 ? 15 
HELX_P HELX_P17 AB8 THR A 337 ? GLY A 355 ? THR M 342 GLY M 360 1 ? 19 
HELX_P HELX_P18 AB9 THR A 373 ? GLY A 384 ? THR M 378 GLY M 389 1 ? 12 
HELX_P HELX_P19 AC1 ASN A 386 ? HIS A 396 ? ASN M 391 HIS M 401 1 ? 11 
HELX_P HELX_P20 AC2 ASN A 411 ? GLU A 443 ? ASN M 416 GLU M 448 1 ? 33 
HELX_P HELX_P21 AC3 SER A 467 ? GLY A 500 ? SER M 472 GLY M 505 1 ? 34 
HELX_P HELX_P22 AC4 GLY A 509 ? ASP A 517 ? GLY M 514 ASP M 522 1 ? 9  
HELX_P HELX_P23 AC5 GLY A 524 ? PHE A 535 ? GLY M 529 PHE M 540 1 ? 12 
HELX_P HELX_P24 AC6 THR A 539 ? LEU A 552 ? THR M 544 LEU M 557 1 ? 14 
HELX_P HELX_P25 AC7 GLY A 587 ? LYS A 593 ? GLY M 592 LYS M 598 1 ? 7  
HELX_P HELX_P26 AC8 ASN A 597 ? LYS A 606 ? ASN M 602 LYS M 611 1 ? 10 
HELX_P HELX_P27 AC9 LYS A 610 ? LEU A 615 ? LYS M 615 LEU M 620 1 ? 6  
HELX_P HELX_P28 AD1 THR A 641 ? ARG A 658 ? THR M 646 ARG M 663 1 ? 18 
HELX_P HELX_P29 AD2 ASP A 680 ? GLY A 692 ? ASP M 685 GLY M 697 1 ? 13 
HELX_P HELX_P30 AD3 GLY A 692 ? ARG A 701 ? GLY M 697 ARG M 706 1 ? 10 
HELX_P HELX_P31 AD4 TYR A 710 ? ARG A 718 ? TYR M 715 ARG M 723 1 ? 9  
HELX_P HELX_P32 AD5 ILE A 719 ? ASN A 721 ? ILE M 724 ASN M 726 5 ? 3  
HELX_P HELX_P33 AD6 ARG A 734 ? SER A 743 ? ARG M 739 SER M 748 1 ? 10 
HELX_P HELX_P34 AD7 LYS A 761 ? LEU A 776 ? LYS M 766 LEU M 781 1 ? 16 
HELX_P HELX_P35 AD8 ASP B 52  ? LYS B 57  ? ASP F 56  LYS F 61  1 ? 6  
HELX_P HELX_P36 AD9 ASN B 74  ? GLU B 89  ? ASN F 78  GLU F 93  1 ? 16 
HELX_P HELX_P37 AE1 ALA B 93  ? HIS B 97  ? ALA F 97  HIS F 101 5 ? 5  
HELX_P HELX_P38 AE2 PRO B 108 ? THR B 122 ? PRO F 112 THR F 126 1 ? 15 
HELX_P HELX_P39 AE3 GLN B 133 ? SER B 141 ? GLN F 137 SER F 145 1 ? 9  
HELX_P HELX_P40 AE4 PRO B 168 ? ILE B 171 ? PRO F 172 ILE F 175 5 ? 4  
HELX_P HELX_P41 AE5 ALA B 177 ? THR B 190 ? ALA F 181 THR F 194 1 ? 14 
HELX_P HELX_P42 AE6 THR B 198 ? CYS B 213 ? THR F 202 CYS F 217 1 ? 16 
HELX_P HELX_P43 AE7 ASP B 218 ? SER B 229 ? ASP F 222 SER F 233 1 ? 12 
HELX_P HELX_P44 AE8 ASN B 248 ? CYS B 253 ? ASN F 252 CYS F 257 1 ? 6  
HELX_P HELX_P45 AE9 PRO B 254 ? PHE B 258 ? PRO F 258 PHE F 262 5 ? 5  
HELX_P HELX_P46 AF1 GLY B 269 ? CYS B 281 ? GLY F 273 CYS F 285 1 ? 13 
HELX_P HELX_P47 AF2 ILE B 285 ? ASN B 292 ? ILE F 289 ASN F 296 1 ? 8  
HELX_P HELX_P48 AF3 GLY B 297 ? TYR B 302 ? GLY F 301 TYR F 306 5 ? 6  
HELX_P HELX_P49 AF4 GLY B 304 ? ALA B 317 ? GLY F 308 ALA F 321 1 ? 14 
HELX_P HELX_P50 AF5 TYR B 333 ? LEU B 345 ? TYR F 337 LEU F 349 1 ? 13 
HELX_P HELX_P51 AF6 SER B 346 ? MET B 351 ? SER F 350 MET F 355 5 ? 6  
HELX_P HELX_P52 AF7 LYS B 355 ? GLY B 362 ? LYS F 359 GLY F 366 1 ? 8  
HELX_P HELX_P53 AF8 PRO B 363 ? ARG B 368 ? PRO F 367 ARG F 372 5 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 3 ? 
AA3 ? 7 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 3 ? 
AB3 ? 3 ? 
AB4 ? 5 ? 
AB5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? parallel      
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? parallel      
AB4 4 5 ? parallel      
AB5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 34  ? PRO A 35  ? VAL M 39  PRO M 40  
AA1 2 PHE A 41  ? VAL A 42  ? PHE M 46  VAL M 47  
AA2 1 ALA A 44  ? ILE A 46  ? ALA M 49  ILE M 51  
AA2 2 ALA A 56  ? THR A 58  ? ALA M 61  THR M 63  
AA2 3 THR A 63  ? VAL A 64  ? THR M 68  VAL M 69  
AA3 1 TYR A 110 ? TYR A 112 ? TYR M 115 TYR M 117 
AA3 2 CYS A 117 ? VAL A 120 ? CYS M 122 VAL M 125 
AA3 3 HIS A 661 ? ILE A 668 ? HIS M 666 ILE M 673 
AA3 4 GLN A 167 ? THR A 172 ? GLN M 172 THR M 177 
AA3 5 GLN A 449 ? LEU A 455 ? GLN M 454 LEU M 460 
AA3 6 PHE A 242 ? PHE A 247 ? PHE M 247 PHE M 252 
AA3 7 LEU A 253 ? GLU A 259 ? LEU M 258 GLU M 264 
AA4 1 ASN A 227 ? ALA A 228 ? ASN M 232 ALA M 233 
AA4 2 SER A 236 ? SER A 237 ? SER M 241 SER M 242 
AA5 1 PHE A 359 ? LEU A 361 ? PHE M 364 LEU M 366 
AA5 2 ALA A 368 ? PRO A 370 ? ALA M 373 PRO M 375 
AA6 1 ARG A 398 ? LYS A 400 ? ARG M 403 LYS M 405 
AA6 2 TYR A 405 ? THR A 407 ? TYR M 410 THR M 412 
AA7 1 PHE A 572 ? HIS A 576 ? PHE M 577 HIS M 581 
AA7 2 GLY A 579 ? TYR A 583 ? GLY M 584 TYR M 588 
AA8 1 ASN A 706 ? LEU A 709 ? ASN M 711 LEU M 714 
AA8 2 LYS A 757 ? PHE A 760 ? LYS M 762 PHE M 765 
AA9 1 LEU B 4   ? CYS B 6   ? LEU F 8   CYS F 10  
AA9 2 THR B 99  ? GLU B 103 ? THR F 103 GLU F 107 
AA9 3 ALA B 127 ? ILE B 132 ? ALA F 131 ILE F 136 
AA9 4 ILE B 353 ? SER B 354 ? ILE F 357 SER F 358 
AB1 1 VAL B 13  ? ALA B 15  ? VAL F 17  ALA F 19  
AB1 2 ALA B 25  ? PHE B 27  ? ALA F 29  PHE F 31  
AB2 1 TYR B 49  ? VAL B 50  ? TYR F 53  VAL F 54  
AB2 2 VAL B 31  ? PRO B 34  ? VAL F 35  PRO F 38  
AB2 3 LEU B 61  ? LYS B 64  ? LEU F 65  LYS F 68  
AB3 1 TYR B 165 ? ALA B 166 ? TYR F 169 ALA F 170 
AB3 2 THR B 156 ? TYR B 162 ? THR F 160 TYR F 166 
AB3 3 MET B 172 ? LEU B 174 ? MET F 176 LEU F 178 
AB4 1 TYR B 165 ? ALA B 166 ? TYR F 169 ALA F 170 
AB4 2 THR B 156 ? TYR B 162 ? THR F 160 TYR F 166 
AB4 3 GLY B 146 ? SER B 151 ? GLY F 150 SER F 155 
AB4 4 ASN B 293 ? SER B 296 ? ASN F 297 SER F 300 
AB4 5 ILE B 325 ? ILE B 326 ? ILE F 329 ILE F 330 
AB5 1 LYS B 234 ? LEU B 238 ? LYS F 238 LEU F 242 
AB5 2 GLY B 241 ? ILE B 246 ? GLY F 245 ILE F 250 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 34  ? N VAL M 39  O VAL A 42  ? O VAL M 47  
AA2 1 2 N LYS A 45  ? N LYS M 50  O GLU A 57  ? O GLU M 62  
AA2 2 3 N ALA A 56  ? N ALA M 61  O VAL A 64  ? O VAL M 69  
AA3 1 2 N THR A 111 ? N THR M 116 O VAL A 118 ? O VAL M 123 
AA3 2 3 N THR A 119 ? N THR M 124 O ARG A 666 ? O ARG M 671 
AA3 3 4 O HIS A 663 ? O HIS M 668 N SER A 168 ? N SER M 173 
AA3 4 5 N ILE A 169 ? N ILE M 174 O GLY A 453 ? O GLY M 458 
AA3 5 6 O GLN A 449 ? O GLN M 454 N PHE A 247 ? N PHE M 252 
AA3 6 7 N ARG A 244 ? N ARG M 249 O ASP A 257 ? O ASP M 262 
AA4 1 2 N ALA A 228 ? N ALA M 233 O SER A 236 ? O SER M 241 
AA5 1 2 N LYS A 360 ? N LYS M 365 O GLU A 369 ? O GLU M 374 
AA6 1 2 N VAL A 399 ? N VAL M 404 O VAL A 406 ? O VAL M 411 
AA7 1 2 N LEU A 574 ? N LEU M 579 O VAL A 581 ? O VAL M 586 
AA8 1 2 N ASN A 706 ? N ASN M 711 O PHE A 760 ? O PHE M 765 
AA9 1 2 N LEU B 4   ? N LEU F 8   O LEU B 100 ? O LEU F 104 
AA9 2 3 N LEU B 101 ? N LEU F 105 O TYR B 129 ? O TYR F 133 
AA9 3 4 N MET B 128 ? N MET F 132 O ILE B 353 ? O ILE F 357 
AB1 1 2 N VAL B 13  ? N VAL F 17  O PHE B 27  ? O PHE F 31  
AB2 1 2 O TYR B 49  ? O TYR F 53  N GLY B 32  ? N GLY F 36  
AB2 2 3 N VAL B 31  ? N VAL F 35  O LYS B 64  ? O LYS F 68  
AB3 1 2 O TYR B 165 ? O TYR F 169 N TYR B 162 ? N TYR F 166 
AB3 2 3 N THR B 156 ? N THR F 160 O LEU B 174 ? O LEU F 178 
AB4 1 2 O TYR B 165 ? O TYR F 169 N TYR B 162 ? N TYR F 166 
AB4 2 3 O HIS B 157 ? O HIS F 161 N ASP B 150 ? N ASP F 154 
AB4 3 4 N LEU B 149 ? N LEU F 153 O VAL B 294 ? O VAL F 298 
AB4 4 5 N ASN B 293 ? N ASN F 297 O ILE B 326 ? O ILE F 330 
AB5 1 2 N TYR B 236 ? N TYR F 240 O ILE B 244 ? O ILE F 248 
# 
_pdbx_entry_details.entry_id                   8ZI9 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OH 
_pdbx_validate_close_contact.auth_asym_id_1   M 
_pdbx_validate_close_contact.auth_comp_id_1   TYR 
_pdbx_validate_close_contact.auth_seq_id_1    162 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   M 
_pdbx_validate_close_contact.auth_comp_id_2   GLY 
_pdbx_validate_close_contact.auth_seq_id_2    256 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN M 44  ? ? -125.11 -169.84 
2  1 PHE M 247 ? ? -162.11 111.99  
3  1 ASP M 282 ? ? -78.01  -167.44 
4  1 LYS M 367 ? ? -79.93  -169.06 
5  1 LYS M 570 ? ? 47.39   29.57   
6  1 LEU M 620 ? ? -97.05  37.17   
7  1 ALA M 622 ? ? -162.58 111.24  
8  1 LYS M 635 ? ? 57.99   7.83    
9  1 MET M 684 ? ? -122.50 -168.13 
10 1 GLU F 72  ? ? -96.20  -66.21  
11 1 ASP F 179 ? ? -93.93  33.62   
12 1 SER F 233 ? ? -74.20  -169.66 
13 1 SER F 234 ? ? -141.67 18.97   
14 1 PRO F 264 ? ? -65.91  2.73    
15 1 SER F 271 ? ? -67.11  -175.51 
16 1 GLU F 334 ? ? -92.56  48.83   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ZI9 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8ZI9 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.08 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               69013 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 'human left ventricle actin and myosin complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8ZI9 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8ZI9 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ZI9 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 M ALA 200 ? A ALA 195 
2  1 Y 1 M ILE 201 ? A ILE 196 
3  1 Y 1 M GLY 202 ? A GLY 197 
4  1 Y 1 M ASP 203 ? A ASP 198 
5  1 Y 1 M ARG 204 ? A ARG 199 
6  1 Y 1 M SER 205 ? A SER 200 
7  1 Y 1 M LYS 206 ? A LYS 201 
8  1 Y 1 M LYS 207 ? A LYS 202 
9  1 Y 1 M ASP 208 ? A ASP 203 
10 1 Y 1 M GLN 209 ? A GLN 204 
11 1 Y 1 M SER 210 ? A SER 205 
12 1 Y 1 M PRO 211 ? A PRO 206 
13 1 Y 1 M GLY 212 ? A GLY 207 
14 1 Y 1 M LYS 213 ? A LYS 208 
15 1 Y 1 M GLY 214 ? A GLY 209 
16 1 Y 1 M THR 215 ? A THR 210 
17 1 Y 1 M ALA 625 ? A ALA 620 
18 1 Y 1 M GLY 626 ? A GLY 621 
19 1 Y 1 M ALA 627 ? A ALA 622 
20 1 Y 1 M ASP 628 ? A ASP 623 
21 1 Y 1 M ALA 629 ? A ALA 624 
22 1 Y 1 M PRO 630 ? A PRO 625 
23 1 Y 1 M ILE 631 ? A ILE 626 
24 1 Y 1 M GLU 632 ? A GLU 627 
25 1 Y 1 M LYS 633 ? A LYS 628 
26 1 Y 1 M ALA 729 ? A ALA 724 
27 1 Y 1 M ILE 730 ? A ILE 725 
28 1 Y 1 M PRO 731 ? A PRO 726 
29 1 Y 1 M GLU 732 ? A GLU 727 
30 1 Y 1 M GLY 733 ? A GLY 728 
31 1 Y 1 M GLN 734 ? A GLN 729 
32 1 Y 1 M PHE 735 ? A PHE 730 
33 1 Y 1 M ILE 736 ? A ILE 731 
34 1 Y 1 M ASP 737 ? A ASP 732 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ADP PB     P N N 1   
ADP O1B    O N N 2   
ADP O2B    O N N 3   
ADP O3B    O N N 4   
ADP PA     P N S 5   
ADP O1A    O N N 6   
ADP O2A    O N N 7   
ADP O3A    O N N 8   
ADP "O5'"  O N N 9   
ADP "C5'"  C N N 10  
ADP "C4'"  C N R 11  
ADP "O4'"  O N N 12  
ADP "C3'"  C N S 13  
ADP "O3'"  O N N 14  
ADP "C2'"  C N R 15  
ADP "O2'"  O N N 16  
ADP "C1'"  C N R 17  
ADP N9     N Y N 18  
ADP C8     C Y N 19  
ADP N7     N Y N 20  
ADP C5     C Y N 21  
ADP C6     C Y N 22  
ADP N6     N N N 23  
ADP N1     N Y N 24  
ADP C2     C Y N 25  
ADP N3     N Y N 26  
ADP C4     C Y N 27  
ADP HOB2   H N N 28  
ADP HOB3   H N N 29  
ADP HOA2   H N N 30  
ADP "H5'1" H N N 31  
ADP "H5'2" H N N 32  
ADP "H4'"  H N N 33  
ADP "H3'"  H N N 34  
ADP "HO3'" H N N 35  
ADP "H2'"  H N N 36  
ADP "HO2'" H N N 37  
ADP "H1'"  H N N 38  
ADP H8     H N N 39  
ADP HN61   H N N 40  
ADP HN62   H N N 41  
ADP H2     H N N 42  
ALA N      N N N 43  
ALA CA     C N S 44  
ALA C      C N N 45  
ALA O      O N N 46  
ALA CB     C N N 47  
ALA OXT    O N N 48  
ALA H      H N N 49  
ALA H2     H N N 50  
ALA HA     H N N 51  
ALA HB1    H N N 52  
ALA HB2    H N N 53  
ALA HB3    H N N 54  
ALA HXT    H N N 55  
ARG N      N N N 56  
ARG CA     C N S 57  
ARG C      C N N 58  
ARG O      O N N 59  
ARG CB     C N N 60  
ARG CG     C N N 61  
ARG CD     C N N 62  
ARG NE     N N N 63  
ARG CZ     C N N 64  
ARG NH1    N N N 65  
ARG NH2    N N N 66  
ARG OXT    O N N 67  
ARG H      H N N 68  
ARG H2     H N N 69  
ARG HA     H N N 70  
ARG HB2    H N N 71  
ARG HB3    H N N 72  
ARG HG2    H N N 73  
ARG HG3    H N N 74  
ARG HD2    H N N 75  
ARG HD3    H N N 76  
ARG HE     H N N 77  
ARG HH11   H N N 78  
ARG HH12   H N N 79  
ARG HH21   H N N 80  
ARG HH22   H N N 81  
ARG HXT    H N N 82  
ASN N      N N N 83  
ASN CA     C N S 84  
ASN C      C N N 85  
ASN O      O N N 86  
ASN CB     C N N 87  
ASN CG     C N N 88  
ASN OD1    O N N 89  
ASN ND2    N N N 90  
ASN OXT    O N N 91  
ASN H      H N N 92  
ASN H2     H N N 93  
ASN HA     H N N 94  
ASN HB2    H N N 95  
ASN HB3    H N N 96  
ASN HD21   H N N 97  
ASN HD22   H N N 98  
ASN HXT    H N N 99  
ASP N      N N N 100 
ASP CA     C N S 101 
ASP C      C N N 102 
ASP O      O N N 103 
ASP CB     C N N 104 
ASP CG     C N N 105 
ASP OD1    O N N 106 
ASP OD2    O N N 107 
ASP OXT    O N N 108 
ASP H      H N N 109 
ASP H2     H N N 110 
ASP HA     H N N 111 
ASP HB2    H N N 112 
ASP HB3    H N N 113 
ASP HD2    H N N 114 
ASP HXT    H N N 115 
CYS N      N N N 116 
CYS CA     C N R 117 
CYS C      C N N 118 
CYS O      O N N 119 
CYS CB     C N N 120 
CYS SG     S N N 121 
CYS OXT    O N N 122 
CYS H      H N N 123 
CYS H2     H N N 124 
CYS HA     H N N 125 
CYS HB2    H N N 126 
CYS HB3    H N N 127 
CYS HG     H N N 128 
CYS HXT    H N N 129 
GLN N      N N N 130 
GLN CA     C N S 131 
GLN C      C N N 132 
GLN O      O N N 133 
GLN CB     C N N 134 
GLN CG     C N N 135 
GLN CD     C N N 136 
GLN OE1    O N N 137 
GLN NE2    N N N 138 
GLN OXT    O N N 139 
GLN H      H N N 140 
GLN H2     H N N 141 
GLN HA     H N N 142 
GLN HB2    H N N 143 
GLN HB3    H N N 144 
GLN HG2    H N N 145 
GLN HG3    H N N 146 
GLN HE21   H N N 147 
GLN HE22   H N N 148 
GLN HXT    H N N 149 
GLU N      N N N 150 
GLU CA     C N S 151 
GLU C      C N N 152 
GLU O      O N N 153 
GLU CB     C N N 154 
GLU CG     C N N 155 
GLU CD     C N N 156 
GLU OE1    O N N 157 
GLU OE2    O N N 158 
GLU OXT    O N N 159 
GLU H      H N N 160 
GLU H2     H N N 161 
GLU HA     H N N 162 
GLU HB2    H N N 163 
GLU HB3    H N N 164 
GLU HG2    H N N 165 
GLU HG3    H N N 166 
GLU HE2    H N N 167 
GLU HXT    H N N 168 
GLY N      N N N 169 
GLY CA     C N N 170 
GLY C      C N N 171 
GLY O      O N N 172 
GLY OXT    O N N 173 
GLY H      H N N 174 
GLY H2     H N N 175 
GLY HA2    H N N 176 
GLY HA3    H N N 177 
GLY HXT    H N N 178 
HIS N      N N N 179 
HIS CA     C N S 180 
HIS C      C N N 181 
HIS O      O N N 182 
HIS CB     C N N 183 
HIS CG     C Y N 184 
HIS ND1    N Y N 185 
HIS CD2    C Y N 186 
HIS CE1    C Y N 187 
HIS NE2    N Y N 188 
HIS OXT    O N N 189 
HIS H      H N N 190 
HIS H2     H N N 191 
HIS HA     H N N 192 
HIS HB2    H N N 193 
HIS HB3    H N N 194 
HIS HD1    H N N 195 
HIS HD2    H N N 196 
HIS HE1    H N N 197 
HIS HE2    H N N 198 
HIS HXT    H N N 199 
ILE N      N N N 200 
ILE CA     C N S 201 
ILE C      C N N 202 
ILE O      O N N 203 
ILE CB     C N S 204 
ILE CG1    C N N 205 
ILE CG2    C N N 206 
ILE CD1    C N N 207 
ILE OXT    O N N 208 
ILE H      H N N 209 
ILE H2     H N N 210 
ILE HA     H N N 211 
ILE HB     H N N 212 
ILE HG12   H N N 213 
ILE HG13   H N N 214 
ILE HG21   H N N 215 
ILE HG22   H N N 216 
ILE HG23   H N N 217 
ILE HD11   H N N 218 
ILE HD12   H N N 219 
ILE HD13   H N N 220 
ILE HXT    H N N 221 
LEU N      N N N 222 
LEU CA     C N S 223 
LEU C      C N N 224 
LEU O      O N N 225 
LEU CB     C N N 226 
LEU CG     C N N 227 
LEU CD1    C N N 228 
LEU CD2    C N N 229 
LEU OXT    O N N 230 
LEU H      H N N 231 
LEU H2     H N N 232 
LEU HA     H N N 233 
LEU HB2    H N N 234 
LEU HB3    H N N 235 
LEU HG     H N N 236 
LEU HD11   H N N 237 
LEU HD12   H N N 238 
LEU HD13   H N N 239 
LEU HD21   H N N 240 
LEU HD22   H N N 241 
LEU HD23   H N N 242 
LEU HXT    H N N 243 
LYS N      N N N 244 
LYS CA     C N S 245 
LYS C      C N N 246 
LYS O      O N N 247 
LYS CB     C N N 248 
LYS CG     C N N 249 
LYS CD     C N N 250 
LYS CE     C N N 251 
LYS NZ     N N N 252 
LYS OXT    O N N 253 
LYS H      H N N 254 
LYS H2     H N N 255 
LYS HA     H N N 256 
LYS HB2    H N N 257 
LYS HB3    H N N 258 
LYS HG2    H N N 259 
LYS HG3    H N N 260 
LYS HD2    H N N 261 
LYS HD3    H N N 262 
LYS HE2    H N N 263 
LYS HE3    H N N 264 
LYS HZ1    H N N 265 
LYS HZ2    H N N 266 
LYS HZ3    H N N 267 
LYS HXT    H N N 268 
MET N      N N N 269 
MET CA     C N S 270 
MET C      C N N 271 
MET O      O N N 272 
MET CB     C N N 273 
MET CG     C N N 274 
MET SD     S N N 275 
MET CE     C N N 276 
MET OXT    O N N 277 
MET H      H N N 278 
MET H2     H N N 279 
MET HA     H N N 280 
MET HB2    H N N 281 
MET HB3    H N N 282 
MET HG2    H N N 283 
MET HG3    H N N 284 
MET HE1    H N N 285 
MET HE2    H N N 286 
MET HE3    H N N 287 
MET HXT    H N N 288 
PHE N      N N N 289 
PHE CA     C N S 290 
PHE C      C N N 291 
PHE O      O N N 292 
PHE CB     C N N 293 
PHE CG     C Y N 294 
PHE CD1    C Y N 295 
PHE CD2    C Y N 296 
PHE CE1    C Y N 297 
PHE CE2    C Y N 298 
PHE CZ     C Y N 299 
PHE OXT    O N N 300 
PHE H      H N N 301 
PHE H2     H N N 302 
PHE HA     H N N 303 
PHE HB2    H N N 304 
PHE HB3    H N N 305 
PHE HD1    H N N 306 
PHE HD2    H N N 307 
PHE HE1    H N N 308 
PHE HE2    H N N 309 
PHE HZ     H N N 310 
PHE HXT    H N N 311 
PRO N      N N N 312 
PRO CA     C N S 313 
PRO C      C N N 314 
PRO O      O N N 315 
PRO CB     C N N 316 
PRO CG     C N N 317 
PRO CD     C N N 318 
PRO OXT    O N N 319 
PRO H      H N N 320 
PRO HA     H N N 321 
PRO HB2    H N N 322 
PRO HB3    H N N 323 
PRO HG2    H N N 324 
PRO HG3    H N N 325 
PRO HD2    H N N 326 
PRO HD3    H N N 327 
PRO HXT    H N N 328 
SER N      N N N 329 
SER CA     C N S 330 
SER C      C N N 331 
SER O      O N N 332 
SER CB     C N N 333 
SER OG     O N N 334 
SER OXT    O N N 335 
SER H      H N N 336 
SER H2     H N N 337 
SER HA     H N N 338 
SER HB2    H N N 339 
SER HB3    H N N 340 
SER HG     H N N 341 
SER HXT    H N N 342 
THR N      N N N 343 
THR CA     C N S 344 
THR C      C N N 345 
THR O      O N N 346 
THR CB     C N R 347 
THR OG1    O N N 348 
THR CG2    C N N 349 
THR OXT    O N N 350 
THR H      H N N 351 
THR H2     H N N 352 
THR HA     H N N 353 
THR HB     H N N 354 
THR HG1    H N N 355 
THR HG21   H N N 356 
THR HG22   H N N 357 
THR HG23   H N N 358 
THR HXT    H N N 359 
TRP N      N N N 360 
TRP CA     C N S 361 
TRP C      C N N 362 
TRP O      O N N 363 
TRP CB     C N N 364 
TRP CG     C Y N 365 
TRP CD1    C Y N 366 
TRP CD2    C Y N 367 
TRP NE1    N Y N 368 
TRP CE2    C Y N 369 
TRP CE3    C Y N 370 
TRP CZ2    C Y N 371 
TRP CZ3    C Y N 372 
TRP CH2    C Y N 373 
TRP OXT    O N N 374 
TRP H      H N N 375 
TRP H2     H N N 376 
TRP HA     H N N 377 
TRP HB2    H N N 378 
TRP HB3    H N N 379 
TRP HD1    H N N 380 
TRP HE1    H N N 381 
TRP HE3    H N N 382 
TRP HZ2    H N N 383 
TRP HZ3    H N N 384 
TRP HH2    H N N 385 
TRP HXT    H N N 386 
TYR N      N N N 387 
TYR CA     C N S 388 
TYR C      C N N 389 
TYR O      O N N 390 
TYR CB     C N N 391 
TYR CG     C Y N 392 
TYR CD1    C Y N 393 
TYR CD2    C Y N 394 
TYR CE1    C Y N 395 
TYR CE2    C Y N 396 
TYR CZ     C Y N 397 
TYR OH     O N N 398 
TYR OXT    O N N 399 
TYR H      H N N 400 
TYR H2     H N N 401 
TYR HA     H N N 402 
TYR HB2    H N N 403 
TYR HB3    H N N 404 
TYR HD1    H N N 405 
TYR HD2    H N N 406 
TYR HE1    H N N 407 
TYR HE2    H N N 408 
TYR HH     H N N 409 
TYR HXT    H N N 410 
VAL N      N N N 411 
VAL CA     C N S 412 
VAL C      C N N 413 
VAL O      O N N 414 
VAL CB     C N N 415 
VAL CG1    C N N 416 
VAL CG2    C N N 417 
VAL OXT    O N N 418 
VAL H      H N N 419 
VAL H2     H N N 420 
VAL HA     H N N 421 
VAL HB     H N N 422 
VAL HG11   H N N 423 
VAL HG12   H N N 424 
VAL HG13   H N N 425 
VAL HG21   H N N 426 
VAL HG22   H N N 427 
VAL HG23   H N N 428 
VAL HXT    H N N 429 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ADP PB    O1B    doub N N 1   
ADP PB    O2B    sing N N 2   
ADP PB    O3B    sing N N 3   
ADP PB    O3A    sing N N 4   
ADP O2B   HOB2   sing N N 5   
ADP O3B   HOB3   sing N N 6   
ADP PA    O1A    doub N N 7   
ADP PA    O2A    sing N N 8   
ADP PA    O3A    sing N N 9   
ADP PA    "O5'"  sing N N 10  
ADP O2A   HOA2   sing N N 11  
ADP "O5'" "C5'"  sing N N 12  
ADP "C5'" "C4'"  sing N N 13  
ADP "C5'" "H5'1" sing N N 14  
ADP "C5'" "H5'2" sing N N 15  
ADP "C4'" "O4'"  sing N N 16  
ADP "C4'" "C3'"  sing N N 17  
ADP "C4'" "H4'"  sing N N 18  
ADP "O4'" "C1'"  sing N N 19  
ADP "C3'" "O3'"  sing N N 20  
ADP "C3'" "C2'"  sing N N 21  
ADP "C3'" "H3'"  sing N N 22  
ADP "O3'" "HO3'" sing N N 23  
ADP "C2'" "O2'"  sing N N 24  
ADP "C2'" "C1'"  sing N N 25  
ADP "C2'" "H2'"  sing N N 26  
ADP "O2'" "HO2'" sing N N 27  
ADP "C1'" N9     sing N N 28  
ADP "C1'" "H1'"  sing N N 29  
ADP N9    C8     sing Y N 30  
ADP N9    C4     sing Y N 31  
ADP C8    N7     doub Y N 32  
ADP C8    H8     sing N N 33  
ADP N7    C5     sing Y N 34  
ADP C5    C6     sing Y N 35  
ADP C5    C4     doub Y N 36  
ADP C6    N6     sing N N 37  
ADP C6    N1     doub Y N 38  
ADP N6    HN61   sing N N 39  
ADP N6    HN62   sing N N 40  
ADP N1    C2     sing Y N 41  
ADP C2    N3     doub Y N 42  
ADP C2    H2     sing N N 43  
ADP N3    C4     sing Y N 44  
ALA N     CA     sing N N 45  
ALA N     H      sing N N 46  
ALA N     H2     sing N N 47  
ALA CA    C      sing N N 48  
ALA CA    CB     sing N N 49  
ALA CA    HA     sing N N 50  
ALA C     O      doub N N 51  
ALA C     OXT    sing N N 52  
ALA CB    HB1    sing N N 53  
ALA CB    HB2    sing N N 54  
ALA CB    HB3    sing N N 55  
ALA OXT   HXT    sing N N 56  
ARG N     CA     sing N N 57  
ARG N     H      sing N N 58  
ARG N     H2     sing N N 59  
ARG CA    C      sing N N 60  
ARG CA    CB     sing N N 61  
ARG CA    HA     sing N N 62  
ARG C     O      doub N N 63  
ARG C     OXT    sing N N 64  
ARG CB    CG     sing N N 65  
ARG CB    HB2    sing N N 66  
ARG CB    HB3    sing N N 67  
ARG CG    CD     sing N N 68  
ARG CG    HG2    sing N N 69  
ARG CG    HG3    sing N N 70  
ARG CD    NE     sing N N 71  
ARG CD    HD2    sing N N 72  
ARG CD    HD3    sing N N 73  
ARG NE    CZ     sing N N 74  
ARG NE    HE     sing N N 75  
ARG CZ    NH1    sing N N 76  
ARG CZ    NH2    doub N N 77  
ARG NH1   HH11   sing N N 78  
ARG NH1   HH12   sing N N 79  
ARG NH2   HH21   sing N N 80  
ARG NH2   HH22   sing N N 81  
ARG OXT   HXT    sing N N 82  
ASN N     CA     sing N N 83  
ASN N     H      sing N N 84  
ASN N     H2     sing N N 85  
ASN CA    C      sing N N 86  
ASN CA    CB     sing N N 87  
ASN CA    HA     sing N N 88  
ASN C     O      doub N N 89  
ASN C     OXT    sing N N 90  
ASN CB    CG     sing N N 91  
ASN CB    HB2    sing N N 92  
ASN CB    HB3    sing N N 93  
ASN CG    OD1    doub N N 94  
ASN CG    ND2    sing N N 95  
ASN ND2   HD21   sing N N 96  
ASN ND2   HD22   sing N N 97  
ASN OXT   HXT    sing N N 98  
ASP N     CA     sing N N 99  
ASP N     H      sing N N 100 
ASP N     H2     sing N N 101 
ASP CA    C      sing N N 102 
ASP CA    CB     sing N N 103 
ASP CA    HA     sing N N 104 
ASP C     O      doub N N 105 
ASP C     OXT    sing N N 106 
ASP CB    CG     sing N N 107 
ASP CB    HB2    sing N N 108 
ASP CB    HB3    sing N N 109 
ASP CG    OD1    doub N N 110 
ASP CG    OD2    sing N N 111 
ASP OD2   HD2    sing N N 112 
ASP OXT   HXT    sing N N 113 
CYS N     CA     sing N N 114 
CYS N     H      sing N N 115 
CYS N     H2     sing N N 116 
CYS CA    C      sing N N 117 
CYS CA    CB     sing N N 118 
CYS CA    HA     sing N N 119 
CYS C     O      doub N N 120 
CYS C     OXT    sing N N 121 
CYS CB    SG     sing N N 122 
CYS CB    HB2    sing N N 123 
CYS CB    HB3    sing N N 124 
CYS SG    HG     sing N N 125 
CYS OXT   HXT    sing N N 126 
GLN N     CA     sing N N 127 
GLN N     H      sing N N 128 
GLN N     H2     sing N N 129 
GLN CA    C      sing N N 130 
GLN CA    CB     sing N N 131 
GLN CA    HA     sing N N 132 
GLN C     O      doub N N 133 
GLN C     OXT    sing N N 134 
GLN CB    CG     sing N N 135 
GLN CB    HB2    sing N N 136 
GLN CB    HB3    sing N N 137 
GLN CG    CD     sing N N 138 
GLN CG    HG2    sing N N 139 
GLN CG    HG3    sing N N 140 
GLN CD    OE1    doub N N 141 
GLN CD    NE2    sing N N 142 
GLN NE2   HE21   sing N N 143 
GLN NE2   HE22   sing N N 144 
GLN OXT   HXT    sing N N 145 
GLU N     CA     sing N N 146 
GLU N     H      sing N N 147 
GLU N     H2     sing N N 148 
GLU CA    C      sing N N 149 
GLU CA    CB     sing N N 150 
GLU CA    HA     sing N N 151 
GLU C     O      doub N N 152 
GLU C     OXT    sing N N 153 
GLU CB    CG     sing N N 154 
GLU CB    HB2    sing N N 155 
GLU CB    HB3    sing N N 156 
GLU CG    CD     sing N N 157 
GLU CG    HG2    sing N N 158 
GLU CG    HG3    sing N N 159 
GLU CD    OE1    doub N N 160 
GLU CD    OE2    sing N N 161 
GLU OE2   HE2    sing N N 162 
GLU OXT   HXT    sing N N 163 
GLY N     CA     sing N N 164 
GLY N     H      sing N N 165 
GLY N     H2     sing N N 166 
GLY CA    C      sing N N 167 
GLY CA    HA2    sing N N 168 
GLY CA    HA3    sing N N 169 
GLY C     O      doub N N 170 
GLY C     OXT    sing N N 171 
GLY OXT   HXT    sing N N 172 
HIS N     CA     sing N N 173 
HIS N     H      sing N N 174 
HIS N     H2     sing N N 175 
HIS CA    C      sing N N 176 
HIS CA    CB     sing N N 177 
HIS CA    HA     sing N N 178 
HIS C     O      doub N N 179 
HIS C     OXT    sing N N 180 
HIS CB    CG     sing N N 181 
HIS CB    HB2    sing N N 182 
HIS CB    HB3    sing N N 183 
HIS CG    ND1    sing Y N 184 
HIS CG    CD2    doub Y N 185 
HIS ND1   CE1    doub Y N 186 
HIS ND1   HD1    sing N N 187 
HIS CD2   NE2    sing Y N 188 
HIS CD2   HD2    sing N N 189 
HIS CE1   NE2    sing Y N 190 
HIS CE1   HE1    sing N N 191 
HIS NE2   HE2    sing N N 192 
HIS OXT   HXT    sing N N 193 
ILE N     CA     sing N N 194 
ILE N     H      sing N N 195 
ILE N     H2     sing N N 196 
ILE CA    C      sing N N 197 
ILE CA    CB     sing N N 198 
ILE CA    HA     sing N N 199 
ILE C     O      doub N N 200 
ILE C     OXT    sing N N 201 
ILE CB    CG1    sing N N 202 
ILE CB    CG2    sing N N 203 
ILE CB    HB     sing N N 204 
ILE CG1   CD1    sing N N 205 
ILE CG1   HG12   sing N N 206 
ILE CG1   HG13   sing N N 207 
ILE CG2   HG21   sing N N 208 
ILE CG2   HG22   sing N N 209 
ILE CG2   HG23   sing N N 210 
ILE CD1   HD11   sing N N 211 
ILE CD1   HD12   sing N N 212 
ILE CD1   HD13   sing N N 213 
ILE OXT   HXT    sing N N 214 
LEU N     CA     sing N N 215 
LEU N     H      sing N N 216 
LEU N     H2     sing N N 217 
LEU CA    C      sing N N 218 
LEU CA    CB     sing N N 219 
LEU CA    HA     sing N N 220 
LEU C     O      doub N N 221 
LEU C     OXT    sing N N 222 
LEU CB    CG     sing N N 223 
LEU CB    HB2    sing N N 224 
LEU CB    HB3    sing N N 225 
LEU CG    CD1    sing N N 226 
LEU CG    CD2    sing N N 227 
LEU CG    HG     sing N N 228 
LEU CD1   HD11   sing N N 229 
LEU CD1   HD12   sing N N 230 
LEU CD1   HD13   sing N N 231 
LEU CD2   HD21   sing N N 232 
LEU CD2   HD22   sing N N 233 
LEU CD2   HD23   sing N N 234 
LEU OXT   HXT    sing N N 235 
LYS N     CA     sing N N 236 
LYS N     H      sing N N 237 
LYS N     H2     sing N N 238 
LYS CA    C      sing N N 239 
LYS CA    CB     sing N N 240 
LYS CA    HA     sing N N 241 
LYS C     O      doub N N 242 
LYS C     OXT    sing N N 243 
LYS CB    CG     sing N N 244 
LYS CB    HB2    sing N N 245 
LYS CB    HB3    sing N N 246 
LYS CG    CD     sing N N 247 
LYS CG    HG2    sing N N 248 
LYS CG    HG3    sing N N 249 
LYS CD    CE     sing N N 250 
LYS CD    HD2    sing N N 251 
LYS CD    HD3    sing N N 252 
LYS CE    NZ     sing N N 253 
LYS CE    HE2    sing N N 254 
LYS CE    HE3    sing N N 255 
LYS NZ    HZ1    sing N N 256 
LYS NZ    HZ2    sing N N 257 
LYS NZ    HZ3    sing N N 258 
LYS OXT   HXT    sing N N 259 
MET N     CA     sing N N 260 
MET N     H      sing N N 261 
MET N     H2     sing N N 262 
MET CA    C      sing N N 263 
MET CA    CB     sing N N 264 
MET CA    HA     sing N N 265 
MET C     O      doub N N 266 
MET C     OXT    sing N N 267 
MET CB    CG     sing N N 268 
MET CB    HB2    sing N N 269 
MET CB    HB3    sing N N 270 
MET CG    SD     sing N N 271 
MET CG    HG2    sing N N 272 
MET CG    HG3    sing N N 273 
MET SD    CE     sing N N 274 
MET CE    HE1    sing N N 275 
MET CE    HE2    sing N N 276 
MET CE    HE3    sing N N 277 
MET OXT   HXT    sing N N 278 
PHE N     CA     sing N N 279 
PHE N     H      sing N N 280 
PHE N     H2     sing N N 281 
PHE CA    C      sing N N 282 
PHE CA    CB     sing N N 283 
PHE CA    HA     sing N N 284 
PHE C     O      doub N N 285 
PHE C     OXT    sing N N 286 
PHE CB    CG     sing N N 287 
PHE CB    HB2    sing N N 288 
PHE CB    HB3    sing N N 289 
PHE CG    CD1    doub Y N 290 
PHE CG    CD2    sing Y N 291 
PHE CD1   CE1    sing Y N 292 
PHE CD1   HD1    sing N N 293 
PHE CD2   CE2    doub Y N 294 
PHE CD2   HD2    sing N N 295 
PHE CE1   CZ     doub Y N 296 
PHE CE1   HE1    sing N N 297 
PHE CE2   CZ     sing Y N 298 
PHE CE2   HE2    sing N N 299 
PHE CZ    HZ     sing N N 300 
PHE OXT   HXT    sing N N 301 
PRO N     CA     sing N N 302 
PRO N     CD     sing N N 303 
PRO N     H      sing N N 304 
PRO CA    C      sing N N 305 
PRO CA    CB     sing N N 306 
PRO CA    HA     sing N N 307 
PRO C     O      doub N N 308 
PRO C     OXT    sing N N 309 
PRO CB    CG     sing N N 310 
PRO CB    HB2    sing N N 311 
PRO CB    HB3    sing N N 312 
PRO CG    CD     sing N N 313 
PRO CG    HG2    sing N N 314 
PRO CG    HG3    sing N N 315 
PRO CD    HD2    sing N N 316 
PRO CD    HD3    sing N N 317 
PRO OXT   HXT    sing N N 318 
SER N     CA     sing N N 319 
SER N     H      sing N N 320 
SER N     H2     sing N N 321 
SER CA    C      sing N N 322 
SER CA    CB     sing N N 323 
SER CA    HA     sing N N 324 
SER C     O      doub N N 325 
SER C     OXT    sing N N 326 
SER CB    OG     sing N N 327 
SER CB    HB2    sing N N 328 
SER CB    HB3    sing N N 329 
SER OG    HG     sing N N 330 
SER OXT   HXT    sing N N 331 
THR N     CA     sing N N 332 
THR N     H      sing N N 333 
THR N     H2     sing N N 334 
THR CA    C      sing N N 335 
THR CA    CB     sing N N 336 
THR CA    HA     sing N N 337 
THR C     O      doub N N 338 
THR C     OXT    sing N N 339 
THR CB    OG1    sing N N 340 
THR CB    CG2    sing N N 341 
THR CB    HB     sing N N 342 
THR OG1   HG1    sing N N 343 
THR CG2   HG21   sing N N 344 
THR CG2   HG22   sing N N 345 
THR CG2   HG23   sing N N 346 
THR OXT   HXT    sing N N 347 
TRP N     CA     sing N N 348 
TRP N     H      sing N N 349 
TRP N     H2     sing N N 350 
TRP CA    C      sing N N 351 
TRP CA    CB     sing N N 352 
TRP CA    HA     sing N N 353 
TRP C     O      doub N N 354 
TRP C     OXT    sing N N 355 
TRP CB    CG     sing N N 356 
TRP CB    HB2    sing N N 357 
TRP CB    HB3    sing N N 358 
TRP CG    CD1    doub Y N 359 
TRP CG    CD2    sing Y N 360 
TRP CD1   NE1    sing Y N 361 
TRP CD1   HD1    sing N N 362 
TRP CD2   CE2    doub Y N 363 
TRP CD2   CE3    sing Y N 364 
TRP NE1   CE2    sing Y N 365 
TRP NE1   HE1    sing N N 366 
TRP CE2   CZ2    sing Y N 367 
TRP CE3   CZ3    doub Y N 368 
TRP CE3   HE3    sing N N 369 
TRP CZ2   CH2    doub Y N 370 
TRP CZ2   HZ2    sing N N 371 
TRP CZ3   CH2    sing Y N 372 
TRP CZ3   HZ3    sing N N 373 
TRP CH2   HH2    sing N N 374 
TRP OXT   HXT    sing N N 375 
TYR N     CA     sing N N 376 
TYR N     H      sing N N 377 
TYR N     H2     sing N N 378 
TYR CA    C      sing N N 379 
TYR CA    CB     sing N N 380 
TYR CA    HA     sing N N 381 
TYR C     O      doub N N 382 
TYR C     OXT    sing N N 383 
TYR CB    CG     sing N N 384 
TYR CB    HB2    sing N N 385 
TYR CB    HB3    sing N N 386 
TYR CG    CD1    doub Y N 387 
TYR CG    CD2    sing Y N 388 
TYR CD1   CE1    sing Y N 389 
TYR CD1   HD1    sing N N 390 
TYR CD2   CE2    doub Y N 391 
TYR CD2   HD2    sing N N 392 
TYR CE1   CZ     doub Y N 393 
TYR CE1   HE1    sing N N 394 
TYR CE2   CZ     sing Y N 395 
TYR CE2   HE2    sing N N 396 
TYR CZ    OH     sing N N 397 
TYR OH    HH     sing N N 398 
TYR OXT   HXT    sing N N 399 
VAL N     CA     sing N N 400 
VAL N     H      sing N N 401 
VAL N     H2     sing N N 402 
VAL CA    C      sing N N 403 
VAL CA    CB     sing N N 404 
VAL CA    HA     sing N N 405 
VAL C     O      doub N N 406 
VAL C     OXT    sing N N 407 
VAL CB    CG1    sing N N 408 
VAL CB    CG2    sing N N 409 
VAL CB    HB     sing N N 410 
VAL CG1   HG11   sing N N 411 
VAL CG1   HG12   sing N N 412 
VAL CG1   HG13   sing N N 413 
VAL CG2   HG21   sing N N 414 
VAL CG2   HG22   sing N N 415 
VAL CG2   HG23   sing N N 416 
VAL OXT   HXT    sing N N 417 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-13 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8ZI9 
_em_admin.last_update        2025-01-29 
_em_admin.map_release_date   2025-01-29 
_em_admin.title              'Human left ventricle actin and myosin complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         55 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOCONTINUUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.15.2_3472: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8ZI9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . MET A 1 1   ? 98.751  183.961 162.479 1.00 175.00 ? 6   MET M N     1 
ATOM   2    C CA    . MET A 1 1   ? 99.487  185.113 161.978 1.00 175.00 ? 6   MET M CA    1 
ATOM   3    C C     . MET A 1 1   ? 98.909  186.415 162.532 1.00 175.00 ? 6   MET M C     1 
ATOM   4    O O     . MET A 1 1   ? 99.399  187.507 162.233 1.00 175.00 ? 6   MET M O     1 
ATOM   5    C CB    . MET A 1 1   ? 99.471  185.134 160.449 1.00 175.00 ? 6   MET M CB    1 
ATOM   6    C CG    . MET A 1 1   ? 100.615 184.365 159.807 1.00 175.00 ? 6   MET M CG    1 
ATOM   7    S SD    . MET A 1 1   ? 102.235 185.072 160.171 1.00 175.00 ? 6   MET M SD    1 
ATOM   8    C CE    . MET A 1 1   ? 102.600 185.926 158.641 1.00 175.00 ? 6   MET M CE    1 
ATOM   9    N N     . ALA A 1 2   ? 97.852  186.288 163.334 1.00 175.09 ? 7   ALA M N     1 
ATOM   10   C CA    . ALA A 1 2   ? 97.267  187.433 164.019 1.00 175.09 ? 7   ALA M CA    1 
ATOM   11   C C     . ALA A 1 2   ? 97.934  187.727 165.356 1.00 175.09 ? 7   ALA M C     1 
ATOM   12   O O     . ALA A 1 2   ? 97.743  188.821 165.896 1.00 175.09 ? 7   ALA M O     1 
ATOM   13   C CB    . ALA A 1 2   ? 95.769  187.207 164.230 1.00 175.09 ? 7   ALA M CB    1 
ATOM   14   N N     . VAL A 1 3   ? 98.715  186.786 165.895 1.00 173.61 ? 8   VAL M N     1 
ATOM   15   C CA    . VAL A 1 3   ? 99.383  186.982 167.177 1.00 173.61 ? 8   VAL M CA    1 
ATOM   16   C C     . VAL A 1 3   ? 100.377 188.130 167.117 1.00 173.61 ? 8   VAL M C     1 
ATOM   17   O O     . VAL A 1 3   ? 100.781 188.658 168.158 1.00 173.61 ? 8   VAL M O     1 
ATOM   18   C CB    . VAL A 1 3   ? 100.070 185.668 167.610 1.00 173.61 ? 8   VAL M CB    1 
ATOM   19   C CG1   . VAL A 1 3   ? 101.288 185.397 166.748 1.00 173.61 ? 8   VAL M CG1   1 
ATOM   20   C CG2   . VAL A 1 3   ? 100.437 185.697 169.090 1.00 173.61 ? 8   VAL M CG2   1 
ATOM   21   N N     . PHE A 1 4   ? 100.762 188.549 165.912 1.00 173.59 ? 9   PHE M N     1 
ATOM   22   C CA    . PHE A 1 4   ? 101.758 189.590 165.705 1.00 173.59 ? 9   PHE M CA    1 
ATOM   23   C C     . PHE A 1 4   ? 101.131 190.967 165.530 1.00 173.59 ? 9   PHE M C     1 
ATOM   24   O O     . PHE A 1 4   ? 101.682 191.798 164.801 1.00 173.59 ? 9   PHE M O     1 
ATOM   25   C CB    . PHE A 1 4   ? 102.614 189.256 164.487 1.00 173.59 ? 9   PHE M CB    1 
ATOM   26   C CG    . PHE A 1 4   ? 103.051 187.827 164.427 1.00 173.59 ? 9   PHE M CG    1 
ATOM   27   C CD1   . PHE A 1 4   ? 103.999 187.340 165.307 1.00 173.59 ? 9   PHE M CD1   1 
ATOM   28   C CD2   . PHE A 1 4   ? 102.506 186.966 163.493 1.00 173.59 ? 9   PHE M CD2   1 
ATOM   29   C CE1   . PHE A 1 4   ? 104.404 186.023 165.246 1.00 173.59 ? 9   PHE M CE1   1 
ATOM   30   C CE2   . PHE A 1 4   ? 102.905 185.649 163.433 1.00 173.59 ? 9   PHE M CE2   1 
ATOM   31   C CZ    . PHE A 1 4   ? 103.856 185.176 164.312 1.00 173.59 ? 9   PHE M CZ    1 
ATOM   32   N N     . GLY A 1 5   ? 99.966  191.195 166.134 1.00 172.43 ? 10  GLY M N     1 
ATOM   33   C CA    . GLY A 1 5   ? 99.339  192.507 166.145 1.00 172.43 ? 10  GLY M CA    1 
ATOM   34   C C     . GLY A 1 5   ? 99.295  193.162 164.785 1.00 172.43 ? 10  GLY M C     1 
ATOM   35   O O     . GLY A 1 5   ? 98.991  192.528 163.768 1.00 172.43 ? 10  GLY M O     1 
ATOM   36   N N     . ALA A 1 6   ? 99.613  194.456 164.760 1.00 172.57 ? 11  ALA M N     1 
ATOM   37   C CA    . ALA A 1 6   ? 99.652  195.221 163.522 1.00 172.57 ? 11  ALA M CA    1 
ATOM   38   C C     . ALA A 1 6   ? 100.991 195.131 162.805 1.00 172.57 ? 11  ALA M C     1 
ATOM   39   O O     . ALA A 1 6   ? 101.065 195.474 161.619 1.00 172.57 ? 11  ALA M O     1 
ATOM   40   C CB    . ALA A 1 6   ? 99.324  196.693 163.801 1.00 172.57 ? 11  ALA M CB    1 
ATOM   41   N N     . ALA A 1 7   ? 102.043 194.677 163.485 1.00 173.79 ? 12  ALA M N     1 
ATOM   42   C CA    . ALA A 1 7   ? 103.359 194.572 162.873 1.00 173.79 ? 12  ALA M CA    1 
ATOM   43   C C     . ALA A 1 7   ? 103.531 193.306 162.052 1.00 173.79 ? 12  ALA M C     1 
ATOM   44   O O     . ALA A 1 7   ? 104.559 193.163 161.383 1.00 173.79 ? 12  ALA M O     1 
ATOM   45   C CB    . ALA A 1 7   ? 104.444 194.629 163.948 1.00 173.79 ? 12  ALA M CB    1 
ATOM   46   N N     . ALA A 1 8   ? 102.557 192.398 162.105 1.00 175.45 ? 13  ALA M N     1 
ATOM   47   C CA    . ALA A 1 8   ? 102.658 191.112 161.418 1.00 175.45 ? 13  ALA M CA    1 
ATOM   48   C C     . ALA A 1 8   ? 103.220 191.175 160.004 1.00 175.45 ? 13  ALA M C     1 
ATOM   49   O O     . ALA A 1 8   ? 104.084 190.342 159.687 1.00 175.45 ? 13  ALA M O     1 
ATOM   50   C CB    . ALA A 1 8   ? 101.279 190.435 161.407 1.00 175.45 ? 13  ALA M CB    1 
ATOM   51   N N     . PRO A 1 9   ? 102.804 192.089 159.118 1.00 175.42 ? 14  PRO M N     1 
ATOM   52   C CA    . PRO A 1 9   ? 103.424 192.108 157.780 1.00 175.42 ? 14  PRO M CA    1 
ATOM   53   C C     . PRO A 1 9   ? 104.918 192.381 157.816 1.00 175.42 ? 14  PRO M C     1 
ATOM   54   O O     . PRO A 1 9   ? 105.700 191.617 157.235 1.00 175.42 ? 14  PRO M O     1 
ATOM   55   C CB    . PRO A 1 9   ? 102.653 193.221 157.059 1.00 175.42 ? 14  PRO M CB    1 
ATOM   56   C CG    . PRO A 1 9   ? 101.355 193.302 157.769 1.00 175.42 ? 14  PRO M CG    1 
ATOM   57   C CD    . PRO A 1 9   ? 101.691 193.050 159.204 1.00 175.42 ? 14  PRO M CD    1 
ATOM   58   N N     . TYR A 1 10  ? 105.340 193.453 158.489 1.00 173.64 ? 15  TYR M N     1 
ATOM   59   C CA    . TYR A 1 10  ? 106.761 193.782 158.531 1.00 173.64 ? 15  TYR M CA    1 
ATOM   60   C C     . TYR A 1 10  ? 107.566 192.689 159.217 1.00 173.64 ? 15  TYR M C     1 
ATOM   61   O O     . TYR A 1 10  ? 108.702 192.404 158.822 1.00 173.64 ? 15  TYR M O     1 
ATOM   62   C CB    . TYR A 1 10  ? 106.971 195.120 159.237 1.00 173.64 ? 15  TYR M CB    1 
ATOM   63   C CG    . TYR A 1 10  ? 106.543 196.310 158.419 1.00 173.64 ? 15  TYR M CG    1 
ATOM   64   C CD1   . TYR A 1 10  ? 107.342 196.787 157.393 1.00 173.64 ? 15  TYR M CD1   1 
ATOM   65   C CD2   . TYR A 1 10  ? 105.344 196.960 158.674 1.00 173.64 ? 15  TYR M CD2   1 
ATOM   66   C CE1   . TYR A 1 10  ? 106.962 197.875 156.642 1.00 173.64 ? 15  TYR M CE1   1 
ATOM   67   C CE2   . TYR A 1 10  ? 104.956 198.052 157.926 1.00 173.64 ? 15  TYR M CE2   1 
ATOM   68   C CZ    . TYR A 1 10  ? 105.772 198.504 156.910 1.00 173.64 ? 15  TYR M CZ    1 
ATOM   69   O OH    . TYR A 1 10  ? 105.406 199.590 156.153 1.00 173.64 ? 15  TYR M OH    1 
ATOM   70   N N     . LEU A 1 11  ? 106.997 192.067 160.248 1.00 174.12 ? 16  LEU M N     1 
ATOM   71   C CA    . LEU A 1 11  ? 107.718 191.019 160.959 1.00 174.12 ? 16  LEU M CA    1 
ATOM   72   C C     . LEU A 1 11  ? 107.845 189.765 160.100 1.00 174.12 ? 16  LEU M C     1 
ATOM   73   O O     . LEU A 1 11  ? 108.902 189.123 160.086 1.00 174.12 ? 16  LEU M O     1 
ATOM   74   C CB    . LEU A 1 11  ? 107.011 190.722 162.282 1.00 174.12 ? 16  LEU M CB    1 
ATOM   75   C CG    . LEU A 1 11  ? 107.815 190.227 163.488 1.00 174.12 ? 16  LEU M CG    1 
ATOM   76   C CD1   . LEU A 1 11  ? 106.928 190.193 164.714 1.00 174.12 ? 16  LEU M CD1   1 
ATOM   77   C CD2   . LEU A 1 11  ? 108.410 188.863 163.251 1.00 174.12 ? 16  LEU M CD2   1 
ATOM   78   N N     . ARG A 1 12  ? 106.786 189.408 159.367 1.00 177.05 ? 17  ARG M N     1 
ATOM   79   C CA    . ARG A 1 12  ? 106.807 188.255 158.473 1.00 177.05 ? 17  ARG M CA    1 
ATOM   80   C C     . ARG A 1 12  ? 105.635 188.280 157.500 1.00 177.05 ? 17  ARG M C     1 
ATOM   81   O O     . ARG A 1 12  ? 104.482 188.417 157.914 1.00 177.05 ? 17  ARG M O     1 
ATOM   82   C CB    . ARG A 1 12  ? 106.779 186.951 159.271 1.00 177.05 ? 17  ARG M CB    1 
ATOM   83   C CG    . ARG A 1 12  ? 107.081 185.723 158.436 1.00 177.05 ? 17  ARG M CG    1 
ATOM   84   C CD    . ARG A 1 12  ? 108.512 185.762 157.930 1.00 177.05 ? 17  ARG M CD    1 
ATOM   85   N NE    . ARG A 1 12  ? 108.801 184.663 157.015 1.00 177.05 ? 17  ARG M NE    1 
ATOM   86   C CZ    . ARG A 1 12  ? 108.863 184.790 155.695 1.00 177.05 ? 17  ARG M CZ    1 
ATOM   87   N NH1   . ARG A 1 12  ? 108.660 185.974 155.130 1.00 177.05 ? 17  ARG M NH1   1 
ATOM   88   N NH2   . ARG A 1 12  ? 109.130 183.733 154.939 1.00 177.05 ? 17  ARG M NH2   1 
ATOM   89   N N     . LYS A 1 13  ? 105.913 188.123 156.209 1.00 178.45 ? 18  LYS M N     1 
ATOM   90   C CA    . LYS A 1 13  ? 104.849 188.105 155.218 1.00 178.45 ? 18  LYS M CA    1 
ATOM   91   C C     . LYS A 1 13  ? 104.079 186.790 155.281 1.00 178.45 ? 18  LYS M C     1 
ATOM   92   O O     . LYS A 1 13  ? 104.609 185.744 155.666 1.00 178.45 ? 18  LYS M O     1 
ATOM   93   C CB    . LYS A 1 13  ? 105.411 188.312 153.813 1.00 178.45 ? 18  LYS M CB    1 
ATOM   94   C CG    . LYS A 1 13  ? 105.330 189.743 153.319 1.00 178.45 ? 18  LYS M CG    1 
ATOM   95   C CD    . LYS A 1 13  ? 106.032 190.686 154.277 1.00 178.45 ? 18  LYS M CD    1 
ATOM   96   C CE    . LYS A 1 13  ? 105.765 192.143 153.942 1.00 178.45 ? 18  LYS M CE    1 
ATOM   97   N NZ    . LYS A 1 13  ? 106.231 193.044 155.031 1.00 178.45 ? 18  LYS M NZ    1 
ATOM   98   N N     . SER A 1 14  ? 102.812 186.853 154.878 1.00 183.68 ? 19  SER M N     1 
ATOM   99   C CA    . SER A 1 14  ? 101.918 185.707 154.965 1.00 183.68 ? 19  SER M CA    1 
ATOM   100  C C     . SER A 1 14  ? 102.329 184.606 153.996 1.00 183.68 ? 19  SER M C     1 
ATOM   101  O O     . SER A 1 14  ? 102.962 184.854 152.966 1.00 183.68 ? 19  SER M O     1 
ATOM   102  C CB    . SER A 1 14  ? 100.479 186.119 154.670 1.00 183.68 ? 19  SER M CB    1 
ATOM   103  O OG    . SER A 1 14  ? 99.720  185.002 154.244 1.00 183.68 ? 19  SER M OG    1 
ATOM   104  N N     . GLU A 1 15  ? 101.954 183.372 154.347 1.00 185.91 ? 20  GLU M N     1 
ATOM   105  C CA    . GLU A 1 15  ? 102.219 182.234 153.475 1.00 185.91 ? 20  GLU M CA    1 
ATOM   106  C C     . GLU A 1 15  ? 101.524 182.400 152.134 1.00 185.91 ? 20  GLU M C     1 
ATOM   107  O O     . GLU A 1 15  ? 102.060 182.007 151.091 1.00 185.91 ? 20  GLU M O     1 
ATOM   108  C CB    . GLU A 1 15  ? 101.774 180.943 154.162 1.00 185.91 ? 20  GLU M CB    1 
ATOM   109  C CG    . GLU A 1 15  ? 101.961 179.685 153.329 1.00 185.91 ? 20  GLU M CG    1 
ATOM   110  C CD    . GLU A 1 15  ? 100.649 179.161 152.777 1.00 185.91 ? 20  GLU M CD    1 
ATOM   111  O OE1   . GLU A 1 15  ? 99.610  179.350 153.441 1.00 185.91 ? 20  GLU M OE1   1 
ATOM   112  O OE2   . GLU A 1 15  ? 100.653 178.567 151.678 1.00 185.91 ? 20  GLU M OE2   1 
ATOM   113  N N     . LYS A 1 16  ? 100.329 182.985 152.141 1.00 186.30 ? 21  LYS M N     1 
ATOM   114  C CA    . LYS A 1 16  ? 99.611  183.205 150.893 1.00 186.30 ? 21  LYS M CA    1 
ATOM   115  C C     . LYS A 1 16  ? 100.414 184.097 149.958 1.00 186.30 ? 21  LYS M C     1 
ATOM   116  O O     . LYS A 1 16  ? 100.647 183.747 148.797 1.00 186.30 ? 21  LYS M O     1 
ATOM   117  C CB    . LYS A 1 16  ? 98.228  183.797 151.182 1.00 186.30 ? 21  LYS M CB    1 
ATOM   118  C CG    . LYS A 1 16  ? 97.332  182.948 152.105 1.00 186.30 ? 21  LYS M CG    1 
ATOM   119  C CD    . LYS A 1 16  ? 97.481  181.431 151.911 1.00 186.30 ? 21  LYS M CD    1 
ATOM   120  C CE    . LYS A 1 16  ? 97.148  180.980 150.486 1.00 186.30 ? 21  LYS M CE    1 
ATOM   121  N NZ    . LYS A 1 16  ? 97.517  179.560 150.238 1.00 186.30 ? 21  LYS M NZ    1 
ATOM   122  N N     . GLU A 1 17  ? 100.863 185.250 150.458 1.00 185.40 ? 22  GLU M N     1 
ATOM   123  C CA    . GLU A 1 17  ? 101.687 186.135 149.643 1.00 185.40 ? 22  GLU M CA    1 
ATOM   124  C C     . GLU A 1 17  ? 103.006 185.479 149.259 1.00 185.40 ? 22  GLU M C     1 
ATOM   125  O O     . GLU A 1 17  ? 103.515 185.707 148.154 1.00 185.40 ? 22  GLU M O     1 
ATOM   126  C CB    . GLU A 1 17  ? 101.944 187.448 150.381 1.00 185.40 ? 22  GLU M CB    1 
ATOM   127  C CG    . GLU A 1 17  ? 102.606 188.503 149.517 1.00 185.40 ? 22  GLU M CG    1 
ATOM   128  C CD    . GLU A 1 17  ? 102.095 188.485 148.089 1.00 185.40 ? 22  GLU M CD    1 
ATOM   129  O OE1   . GLU A 1 17  ? 102.914 188.299 147.167 1.00 185.40 ? 22  GLU M OE1   1 
ATOM   130  O OE2   . GLU A 1 17  ? 100.873 188.648 147.887 1.00 185.40 ? 22  GLU M OE2   1 
ATOM   131  N N     . ARG A 1 18  ? 103.570 184.665 150.149 1.00 184.84 ? 23  ARG M N     1 
ATOM   132  C CA    . ARG A 1 18  ? 104.770 183.913 149.804 1.00 184.84 ? 23  ARG M CA    1 
ATOM   133  C C     . ARG A 1 18  ? 104.536 183.074 148.557 1.00 184.84 ? 23  ARG M C     1 
ATOM   134  O O     . ARG A 1 18  ? 105.309 183.138 147.596 1.00 184.84 ? 23  ARG M O     1 
ATOM   135  C CB    . ARG A 1 18  ? 105.188 183.026 150.976 1.00 184.84 ? 23  ARG M CB    1 
ATOM   136  C CG    . ARG A 1 18  ? 105.982 183.744 152.048 1.00 184.84 ? 23  ARG M CG    1 
ATOM   137  C CD    . ARG A 1 18  ? 106.586 182.754 153.035 1.00 184.84 ? 23  ARG M CD    1 
ATOM   138  N NE    . ARG A 1 18  ? 105.586 182.196 153.939 1.00 184.84 ? 23  ARG M NE    1 
ATOM   139  C CZ    . ARG A 1 18  ? 105.257 182.739 155.105 1.00 184.84 ? 23  ARG M CZ    1 
ATOM   140  N NH1   . ARG A 1 18  ? 105.841 183.858 155.504 1.00 184.84 ? 23  ARG M NH1   1 
ATOM   141  N NH2   . ARG A 1 18  ? 104.340 182.169 155.873 1.00 184.84 ? 23  ARG M NH2   1 
ATOM   142  N N     . LEU A 1 19  ? 103.453 182.299 148.547 1.00 186.15 ? 24  LEU M N     1 
ATOM   143  C CA    . LEU A 1 19  ? 103.175 181.442 147.399 1.00 186.15 ? 24  LEU M CA    1 
ATOM   144  C C     . LEU A 1 19  ? 102.828 182.262 146.160 1.00 186.15 ? 24  LEU M C     1 
ATOM   145  O O     . LEU A 1 19  ? 103.204 181.891 145.043 1.00 186.15 ? 24  LEU M O     1 
ATOM   146  C CB    . LEU A 1 19  ? 102.054 180.456 147.729 1.00 186.15 ? 24  LEU M CB    1 
ATOM   147  C CG    . LEU A 1 19  ? 102.425 179.153 148.451 1.00 186.15 ? 24  LEU M CG    1 
ATOM   148  C CD1   . LEU A 1 19  ? 103.284 178.270 147.552 1.00 186.15 ? 24  LEU M CD1   1 
ATOM   149  C CD2   . LEU A 1 19  ? 103.120 179.392 149.782 1.00 186.15 ? 24  LEU M CD2   1 
ATOM   150  N N     . GLU A 1 20  ? 102.122 183.384 146.334 1.00 187.13 ? 25  GLU M N     1 
ATOM   151  C CA    . GLU A 1 20  ? 101.794 184.223 145.184 1.00 187.13 ? 25  GLU M CA    1 
ATOM   152  C C     . GLU A 1 20  ? 103.040 184.856 144.581 1.00 187.13 ? 25  GLU M C     1 
ATOM   153  O O     . GLU A 1 20  ? 103.046 185.200 143.393 1.00 187.13 ? 25  GLU M O     1 
ATOM   154  C CB    . GLU A 1 20  ? 100.789 185.312 145.566 1.00 187.13 ? 25  GLU M CB    1 
ATOM   155  C CG    . GLU A 1 20  ? 99.521  184.817 146.247 1.00 187.13 ? 25  GLU M CG    1 
ATOM   156  C CD    . GLU A 1 20  ? 99.072  183.457 145.750 1.00 187.13 ? 25  GLU M CD    1 
ATOM   157  O OE1   . GLU A 1 20  ? 98.756  183.332 144.548 1.00 187.13 ? 25  GLU M OE1   1 
ATOM   158  O OE2   . GLU A 1 20  ? 99.040  182.510 146.564 1.00 187.13 ? 25  GLU M OE2   1 
ATOM   159  N N     . ALA A 1 21  ? 104.090 185.029 145.380 1.00 186.73 ? 26  ALA M N     1 
ATOM   160  C CA    . ALA A 1 21  ? 105.369 185.494 144.864 1.00 186.73 ? 26  ALA M CA    1 
ATOM   161  C C     . ALA A 1 21  ? 106.250 184.360 144.359 1.00 186.73 ? 26  ALA M C     1 
ATOM   162  O O     . ALA A 1 21  ? 107.186 184.615 143.592 1.00 186.73 ? 26  ALA M O     1 
ATOM   163  C CB    . ALA A 1 21  ? 106.118 186.277 145.946 1.00 186.73 ? 26  ALA M CB    1 
ATOM   164  N N     . GLN A 1 22  ? 105.983 183.122 144.785 1.00 185.85 ? 27  GLN M N     1 
ATOM   165  C CA    . GLN A 1 22  ? 106.779 181.992 144.312 1.00 185.85 ? 27  GLN M CA    1 
ATOM   166  C C     . GLN A 1 22  ? 106.674 181.837 142.803 1.00 185.85 ? 27  GLN M C     1 
ATOM   167  O O     . GLN A 1 22  ? 107.659 181.503 142.135 1.00 185.85 ? 27  GLN M O     1 
ATOM   168  C CB    . GLN A 1 22  ? 106.342 180.698 145.002 1.00 185.85 ? 27  GLN M CB    1 
ATOM   169  C CG    . GLN A 1 22  ? 106.585 180.653 146.500 1.00 185.85 ? 27  GLN M CG    1 
ATOM   170  C CD    . GLN A 1 22  ? 107.886 181.315 146.910 1.00 185.85 ? 27  GLN M CD    1 
ATOM   171  O OE1   . GLN A 1 22  ? 108.938 180.679 146.934 1.00 185.85 ? 27  GLN M OE1   1 
ATOM   172  N NE2   . GLN A 1 22  ? 107.816 182.599 147.249 1.00 185.85 ? 27  GLN M NE2   1 
ATOM   173  N N     . THR A 1 23  ? 105.491 182.078 142.250 1.00 187.36 ? 28  THR M N     1 
ATOM   174  C CA    . THR A 1 23  ? 105.267 181.918 140.817 1.00 187.36 ? 28  THR M CA    1 
ATOM   175  C C     . THR A 1 23  ? 105.997 183.033 140.079 1.00 187.36 ? 28  THR M C     1 
ATOM   176  O O     . THR A 1 23  ? 105.503 184.158 139.983 1.00 187.36 ? 28  THR M O     1 
ATOM   177  C CB    . THR A 1 23  ? 103.775 181.940 140.505 1.00 187.36 ? 28  THR M CB    1 
ATOM   178  O OG1   . THR A 1 23  ? 103.063 181.193 141.500 1.00 187.36 ? 28  THR M OG1   1 
ATOM   179  C CG2   . THR A 1 23  ? 103.512 181.321 139.139 1.00 187.36 ? 28  THR M CG2   1 
ATOM   180  N N     . ARG A 1 24  ? 107.186 182.723 139.555 1.00 186.06 ? 29  ARG M N     1 
ATOM   181  C CA    . ARG A 1 24  ? 107.950 183.697 138.790 1.00 186.06 ? 29  ARG M CA    1 
ATOM   182  C C     . ARG A 1 24  ? 108.987 182.958 137.966 1.00 186.06 ? 29  ARG M C     1 
ATOM   183  O O     . ARG A 1 24  ? 109.654 182.062 138.498 1.00 186.06 ? 29  ARG M O     1 
ATOM   184  C CB    . ARG A 1 24  ? 108.628 184.724 139.706 1.00 186.06 ? 29  ARG M CB    1 
ATOM   185  C CG    . ARG A 1 24  ? 109.335 185.860 138.975 1.00 186.06 ? 29  ARG M CG    1 
ATOM   186  C CD    . ARG A 1 24  ? 110.843 185.728 139.096 1.00 186.06 ? 29  ARG M CD    1 
ATOM   187  N NE    . ARG A 1 24  ? 111.268 185.588 140.486 1.00 186.06 ? 29  ARG M NE    1 
ATOM   188  C CZ    . ARG A 1 24  ? 112.495 185.242 140.863 1.00 186.06 ? 29  ARG M CZ    1 
ATOM   189  N NH1   . ARG A 1 24  ? 113.426 184.997 139.953 1.00 186.06 ? 29  ARG M NH1   1 
ATOM   190  N NH2   . ARG A 1 24  ? 112.791 185.139 142.152 1.00 186.06 ? 29  ARG M NH2   1 
ATOM   191  N N     . PRO A 1 25  ? 109.147 183.289 136.686 1.00 186.92 ? 30  PRO M N     1 
ATOM   192  C CA    . PRO A 1 25  ? 110.143 182.593 135.866 1.00 186.92 ? 30  PRO M CA    1 
ATOM   193  C C     . PRO A 1 25  ? 111.558 183.004 136.237 1.00 186.92 ? 30  PRO M C     1 
ATOM   194  O O     . PRO A 1 25  ? 111.848 184.182 136.463 1.00 186.92 ? 30  PRO M O     1 
ATOM   195  C CB    . PRO A 1 25  ? 109.798 183.029 134.435 1.00 186.92 ? 30  PRO M CB    1 
ATOM   196  C CG    . PRO A 1 25  ? 108.444 183.664 134.521 1.00 186.92 ? 30  PRO M CG    1 
ATOM   197  C CD    . PRO A 1 25  ? 108.358 184.242 135.892 1.00 186.92 ? 30  PRO M CD    1 
ATOM   198  N N     . PHE A 1 26  ? 112.444 182.013 136.288 1.00 188.22 ? 31  PHE M N     1 
ATOM   199  C CA    . PHE A 1 26  ? 113.858 182.254 136.556 1.00 188.22 ? 31  PHE M CA    1 
ATOM   200  C C     . PHE A 1 26  ? 114.658 181.161 135.871 1.00 188.22 ? 31  PHE M C     1 
ATOM   201  O O     . PHE A 1 26  ? 114.453 179.977 136.156 1.00 188.22 ? 31  PHE M O     1 
ATOM   202  C CB    . PHE A 1 26  ? 114.146 182.272 138.055 1.00 188.22 ? 31  PHE M CB    1 
ATOM   203  C CG    . PHE A 1 26  ? 115.614 182.209 138.386 1.00 188.22 ? 31  PHE M CG    1 
ATOM   204  C CD1   . PHE A 1 26  ? 116.448 183.285 138.113 1.00 188.22 ? 31  PHE M CD1   1 
ATOM   205  C CD2   . PHE A 1 26  ? 116.159 181.072 138.963 1.00 188.22 ? 31  PHE M CD2   1 
ATOM   206  C CE1   . PHE A 1 26  ? 117.797 183.228 138.411 1.00 188.22 ? 31  PHE M CE1   1 
ATOM   207  C CE2   . PHE A 1 26  ? 117.505 181.011 139.264 1.00 188.22 ? 31  PHE M CE2   1 
ATOM   208  C CZ    . PHE A 1 26  ? 118.324 182.091 138.989 1.00 188.22 ? 31  PHE M CZ    1 
ATOM   209  N N     . ASP A 1 27  ? 115.561 181.550 134.975 1.00 189.25 ? 32  ASP M N     1 
ATOM   210  C CA    . ASP A 1 27  ? 116.388 180.594 134.254 1.00 189.25 ? 32  ASP M CA    1 
ATOM   211  C C     . ASP A 1 27  ? 117.644 180.305 135.069 1.00 189.25 ? 32  ASP M C     1 
ATOM   212  O O     . ASP A 1 27  ? 118.441 181.209 135.344 1.00 189.25 ? 32  ASP M O     1 
ATOM   213  C CB    . ASP A 1 27  ? 116.746 181.117 132.863 1.00 189.25 ? 32  ASP M CB    1 
ATOM   214  C CG    . ASP A 1 27  ? 117.570 180.123 132.061 1.00 189.25 ? 32  ASP M CG    1 
ATOM   215  O OD1   . ASP A 1 27  ? 118.752 179.908 132.400 1.00 189.25 ? 32  ASP M OD1   1 
ATOM   216  O OD2   . ASP A 1 27  ? 117.031 179.544 131.094 1.00 189.25 ? 32  ASP M OD2   1 
ATOM   217  N N     . LEU A 1 28  ? 117.815 179.039 135.445 1.00 189.93 ? 33  LEU M N     1 
ATOM   218  C CA    . LEU A 1 28  ? 118.939 178.619 136.267 1.00 189.93 ? 33  LEU M CA    1 
ATOM   219  C C     . LEU A 1 28  ? 120.256 178.589 135.505 1.00 189.93 ? 33  LEU M C     1 
ATOM   220  O O     . LEU A 1 28  ? 121.301 178.363 136.123 1.00 189.93 ? 33  LEU M O     1 
ATOM   221  C CB    . LEU A 1 28  ? 118.658 177.235 136.856 1.00 189.93 ? 33  LEU M CB    1 
ATOM   222  C CG    . LEU A 1 28  ? 117.411 177.085 137.731 1.00 189.93 ? 33  LEU M CG    1 
ATOM   223  C CD1   . LEU A 1 28  ? 116.175 176.734 136.907 1.00 189.93 ? 33  LEU M CD1   1 
ATOM   224  C CD2   . LEU A 1 28  ? 117.653 176.041 138.807 1.00 189.93 ? 33  LEU M CD2   1 
ATOM   225  N N     . LYS A 1 29  ? 120.236 178.799 134.190 1.00 188.58 ? 34  LYS M N     1 
ATOM   226  C CA    . LYS A 1 29  ? 121.455 178.665 133.400 1.00 188.58 ? 34  LYS M CA    1 
ATOM   227  C C     . LYS A 1 29  ? 122.042 180.007 132.987 1.00 188.58 ? 34  LYS M C     1 
ATOM   228  O O     . LYS A 1 29  ? 123.266 180.178 133.011 1.00 188.58 ? 34  LYS M O     1 
ATOM   229  C CB    . LYS A 1 29  ? 121.189 177.814 132.150 1.00 188.58 ? 34  LYS M CB    1 
ATOM   230  C CG    . LYS A 1 29  ? 120.570 176.426 132.392 1.00 188.58 ? 34  LYS M CG    1 
ATOM   231  C CD    . LYS A 1 29  ? 121.042 175.729 133.670 1.00 188.58 ? 34  LYS M CD    1 
ATOM   232  C CE    . LYS A 1 29  ? 122.554 175.521 133.708 1.00 188.58 ? 34  LYS M CE    1 
ATOM   233  N NZ    . LYS A 1 29  ? 122.993 175.003 135.030 1.00 188.58 ? 34  LYS M NZ    1 
ATOM   234  N N     . LYS A 1 30  ? 121.202 180.964 132.596 1.00 188.90 ? 35  LYS M N     1 
ATOM   235  C CA    . LYS A 1 30  ? 121.693 182.197 131.996 1.00 188.90 ? 35  LYS M CA    1 
ATOM   236  C C     . LYS A 1 30  ? 121.261 183.455 132.743 1.00 188.90 ? 35  LYS M C     1 
ATOM   237  O O     . LYS A 1 30  ? 121.336 184.549 132.174 1.00 188.90 ? 35  LYS M O     1 
ATOM   238  C CB    . LYS A 1 30  ? 121.251 182.280 130.532 1.00 188.90 ? 35  LYS M CB    1 
ATOM   239  C CG    . LYS A 1 30  ? 121.975 181.296 129.627 1.00 188.90 ? 35  LYS M CG    1 
ATOM   240  C CD    . LYS A 1 30  ? 123.485 181.434 129.753 1.00 188.90 ? 35  LYS M CD    1 
ATOM   241  C CE    . LYS A 1 30  ? 124.223 180.598 128.713 1.00 188.90 ? 35  LYS M CE    1 
ATOM   242  N NZ    . LYS A 1 30  ? 123.857 179.156 128.783 1.00 188.90 ? 35  LYS M NZ    1 
ATOM   243  N N     . ASP A 1 31  ? 120.807 183.331 133.990 1.00 188.17 ? 36  ASP M N     1 
ATOM   244  C CA    . ASP A 1 31  ? 120.515 184.473 134.849 1.00 188.17 ? 36  ASP M CA    1 
ATOM   245  C C     . ASP A 1 31  ? 121.404 184.484 136.090 1.00 188.17 ? 36  ASP M C     1 
ATOM   246  O O     . ASP A 1 31  ? 121.021 185.010 137.138 1.00 188.17 ? 36  ASP M O     1 
ATOM   247  C CB    . ASP A 1 31  ? 119.040 184.484 135.245 1.00 188.17 ? 36  ASP M CB    1 
ATOM   248  C CG    . ASP A 1 31  ? 118.147 185.015 134.143 1.00 188.17 ? 36  ASP M CG    1 
ATOM   249  O OD1   . ASP A 1 31  ? 117.720 184.219 133.281 1.00 188.17 ? 36  ASP M OD1   1 
ATOM   250  O OD2   . ASP A 1 31  ? 117.872 186.231 134.137 1.00 188.17 ? 36  ASP M OD2   1 
ATOM   251  N N     . VAL A 1 32  ? 122.597 183.909 135.976 1.00 186.81 ? 37  VAL M N     1 
ATOM   252  C CA    . VAL A 1 32  ? 123.511 183.719 137.097 1.00 186.81 ? 37  VAL M CA    1 
ATOM   253  C C     . VAL A 1 32  ? 124.075 185.063 137.544 1.00 186.81 ? 37  VAL M C     1 
ATOM   254  O O     . VAL A 1 32  ? 123.925 186.071 136.844 1.00 186.81 ? 37  VAL M O     1 
ATOM   255  C CB    . VAL A 1 32  ? 124.635 182.745 136.701 1.00 186.81 ? 37  VAL M CB    1 
ATOM   256  C CG1   . VAL A 1 32  ? 124.076 181.344 136.510 1.00 186.81 ? 37  VAL M CG1   1 
ATOM   257  C CG2   . VAL A 1 32  ? 125.316 183.216 135.431 1.00 186.81 ? 37  VAL M CG2   1 
ATOM   258  N N     . PHE A 1 33  ? 124.720 185.096 138.710 1.00 184.61 ? 38  PHE M N     1 
ATOM   259  C CA    . PHE A 1 33  ? 125.328 186.337 139.173 1.00 184.61 ? 38  PHE M CA    1 
ATOM   260  C C     . PHE A 1 33  ? 126.552 186.692 138.341 1.00 184.61 ? 38  PHE M C     1 
ATOM   261  O O     . PHE A 1 33  ? 127.365 185.830 137.990 1.00 184.61 ? 38  PHE M O     1 
ATOM   262  C CB    . PHE A 1 33  ? 125.713 186.259 140.648 1.00 184.61 ? 38  PHE M CB    1 
ATOM   263  C CG    . PHE A 1 33  ? 124.562 186.477 141.587 1.00 184.61 ? 38  PHE M CG    1 
ATOM   264  C CD1   . PHE A 1 33  ? 124.008 187.741 141.728 1.00 184.61 ? 38  PHE M CD1   1 
ATOM   265  C CD2   . PHE A 1 33  ? 124.075 185.449 142.373 1.00 184.61 ? 38  PHE M CD2   1 
ATOM   266  C CE1   . PHE A 1 33  ? 122.960 187.964 142.600 1.00 184.61 ? 38  PHE M CE1   1 
ATOM   267  C CE2   . PHE A 1 33  ? 123.029 185.667 143.251 1.00 184.61 ? 38  PHE M CE2   1 
ATOM   268  C CZ    . PHE A 1 33  ? 122.471 186.929 143.362 1.00 184.61 ? 38  PHE M CZ    1 
ATOM   269  N N     . VAL A 1 34  ? 126.690 187.981 138.053 1.00 185.17 ? 39  VAL M N     1 
ATOM   270  C CA    . VAL A 1 34  ? 127.691 188.479 137.116 1.00 185.17 ? 39  VAL M CA    1 
ATOM   271  C C     . VAL A 1 34  ? 128.413 189.674 137.724 1.00 185.17 ? 39  VAL M C     1 
ATOM   272  O O     . VAL A 1 34  ? 127.768 190.565 138.292 1.00 185.17 ? 39  VAL M O     1 
ATOM   273  C CB    . VAL A 1 34  ? 127.043 188.839 135.769 1.00 185.17 ? 39  VAL M CB    1 
ATOM   274  C CG1   . VAL A 1 34  ? 125.943 189.871 135.958 1.00 185.17 ? 39  VAL M CG1   1 
ATOM   275  C CG2   . VAL A 1 34  ? 128.081 189.373 134.812 1.00 185.17 ? 39  VAL M CG2   1 
ATOM   276  N N     . PRO A 1 35  ? 129.743 189.722 137.652 1.00 184.59 ? 40  PRO M N     1 
ATOM   277  C CA    . PRO A 1 35  ? 130.466 190.899 138.142 1.00 184.59 ? 40  PRO M CA    1 
ATOM   278  C C     . PRO A 1 35  ? 130.051 192.158 137.396 1.00 184.59 ? 40  PRO M C     1 
ATOM   279  O O     . PRO A 1 35  ? 129.594 192.117 136.251 1.00 184.59 ? 40  PRO M O     1 
ATOM   280  C CB    . PRO A 1 35  ? 131.935 190.551 137.879 1.00 184.59 ? 40  PRO M CB    1 
ATOM   281  C CG    . PRO A 1 35  ? 131.963 189.060 137.830 1.00 184.59 ? 40  PRO M CG    1 
ATOM   282  C CD    . PRO A 1 35  ? 130.656 188.652 137.221 1.00 184.59 ? 40  PRO M CD    1 
ATOM   283  N N     . ASP A 1 36  ? 130.218 193.293 138.067 1.00 182.05 ? 41  ASP M N     1 
ATOM   284  C CA    . ASP A 1 36  ? 129.766 194.579 137.561 1.00 182.05 ? 41  ASP M CA    1 
ATOM   285  C C     . ASP A 1 36  ? 130.871 195.614 137.737 1.00 182.05 ? 41  ASP M C     1 
ATOM   286  O O     . ASP A 1 36  ? 131.866 195.385 138.427 1.00 182.05 ? 41  ASP M O     1 
ATOM   287  C CB    . ASP A 1 36  ? 128.472 195.015 138.269 1.00 182.05 ? 41  ASP M CB    1 
ATOM   288  C CG    . ASP A 1 36  ? 127.960 196.358 137.789 1.00 182.05 ? 41  ASP M CG    1 
ATOM   289  O OD1   . ASP A 1 36  ? 127.087 196.388 136.897 1.00 182.05 ? 41  ASP M OD1   1 
ATOM   290  O OD2   . ASP A 1 36  ? 128.438 197.387 138.310 1.00 182.05 ? 41  ASP M OD2   1 
ATOM   291  N N     . ASP A 1 37  ? 130.692 196.761 137.082 1.00 181.29 ? 42  ASP M N     1 
ATOM   292  C CA    . ASP A 1 37  ? 131.579 197.910 137.211 1.00 181.29 ? 42  ASP M CA    1 
ATOM   293  C C     . ASP A 1 37  ? 131.051 198.933 138.209 1.00 181.29 ? 42  ASP M C     1 
ATOM   294  O O     . ASP A 1 37  ? 131.734 199.251 139.187 1.00 181.29 ? 42  ASP M O     1 
ATOM   295  C CB    . ASP A 1 37  ? 131.778 198.563 135.834 1.00 181.29 ? 42  ASP M CB    1 
ATOM   296  C CG    . ASP A 1 37  ? 132.815 199.680 135.842 1.00 181.29 ? 42  ASP M CG    1 
ATOM   297  O OD1   . ASP A 1 37  ? 133.643 199.708 134.907 1.00 181.29 ? 42  ASP M OD1   1 
ATOM   298  O OD2   . ASP A 1 37  ? 132.799 200.540 136.750 1.00 181.29 ? 42  ASP M OD2   1 
ATOM   299  N N     . LYS A 1 38  ? 129.841 199.454 137.980 1.00 180.35 ? 43  LYS M N     1 
ATOM   300  C CA    . LYS A 1 38  ? 129.276 200.453 138.884 1.00 180.35 ? 43  LYS M CA    1 
ATOM   301  C C     . LYS A 1 38  ? 129.018 199.864 140.263 1.00 180.35 ? 43  LYS M C     1 
ATOM   302  O O     . LYS A 1 38  ? 129.160 200.554 141.279 1.00 180.35 ? 43  LYS M O     1 
ATOM   303  C CB    . LYS A 1 38  ? 127.988 201.025 138.293 1.00 180.35 ? 43  LYS M CB    1 
ATOM   304  C CG    . LYS A 1 38  ? 128.199 202.205 137.352 1.00 180.35 ? 43  LYS M CG    1 
ATOM   305  C CD    . LYS A 1 38  ? 128.713 203.430 138.102 1.00 180.35 ? 43  LYS M CD    1 
ATOM   306  C CE    . LYS A 1 38  ? 127.752 203.856 139.203 1.00 180.35 ? 43  LYS M CE    1 
ATOM   307  N NZ    . LYS A 1 38  ? 128.448 204.550 140.320 1.00 180.35 ? 43  LYS M NZ    1 
ATOM   308  N N     . GLN A 1 39  ? 128.632 198.597 140.313 1.00 179.55 ? 44  GLN M N     1 
ATOM   309  C CA    . GLN A 1 39  ? 128.509 197.823 141.537 1.00 179.55 ? 44  GLN M CA    1 
ATOM   310  C C     . GLN A 1 39  ? 129.352 196.560 141.386 1.00 179.55 ? 44  GLN M C     1 
ATOM   311  O O     . GLN A 1 39  ? 130.147 196.431 140.454 1.00 179.55 ? 44  GLN M O     1 
ATOM   312  C CB    . GLN A 1 39  ? 127.045 197.505 141.843 1.00 179.55 ? 44  GLN M CB    1 
ATOM   313  C CG    . GLN A 1 39  ? 126.319 198.590 142.627 1.00 179.55 ? 44  GLN M CG    1 
ATOM   314  C CD    . GLN A 1 39  ? 125.850 199.745 141.768 1.00 179.55 ? 44  GLN M CD    1 
ATOM   315  O OE1   . GLN A 1 39  ? 125.927 199.697 140.542 1.00 179.55 ? 44  GLN M OE1   1 
ATOM   316  N NE2   . GLN A 1 39  ? 125.345 200.791 142.413 1.00 179.55 ? 44  GLN M NE2   1 
ATOM   317  N N     . GLU A 1 40  ? 129.193 195.631 142.328 1.00 179.18 ? 45  GLU M N     1 
ATOM   318  C CA    . GLU A 1 40  ? 129.987 194.408 142.292 1.00 179.18 ? 45  GLU M CA    1 
ATOM   319  C C     . GLU A 1 40  ? 129.322 193.330 141.450 1.00 179.18 ? 45  GLU M C     1 
ATOM   320  O O     . GLU A 1 40  ? 129.991 192.647 140.667 1.00 179.18 ? 45  GLU M O     1 
ATOM   321  C CB    . GLU A 1 40  ? 130.229 193.903 143.714 1.00 179.18 ? 45  GLU M CB    1 
ATOM   322  C CG    . GLU A 1 40  ? 129.054 193.179 144.393 1.00 179.18 ? 45  GLU M CG    1 
ATOM   323  C CD    . GLU A 1 40  ? 127.773 194.002 144.474 1.00 179.18 ? 45  GLU M CD    1 
ATOM   324  O OE1   . GLU A 1 40  ? 127.833 195.243 144.339 1.00 179.18 ? 45  GLU M OE1   1 
ATOM   325  O OE2   . GLU A 1 40  ? 126.698 193.397 144.674 1.00 179.18 ? 45  GLU M OE2   1 
ATOM   326  N N     . PHE A 1 41  ? 128.011 193.177 141.596 1.00 182.61 ? 46  PHE M N     1 
ATOM   327  C CA    . PHE A 1 41  ? 127.237 192.126 140.961 1.00 182.61 ? 46  PHE M CA    1 
ATOM   328  C C     . PHE A 1 41  ? 125.852 192.690 140.703 1.00 182.61 ? 46  PHE M C     1 
ATOM   329  O O     . PHE A 1 41  ? 125.246 193.287 141.595 1.00 182.61 ? 46  PHE M O     1 
ATOM   330  C CB    . PHE A 1 41  ? 127.139 190.877 141.844 1.00 182.61 ? 46  PHE M CB    1 
ATOM   331  C CG    . PHE A 1 41  ? 128.380 190.024 141.856 1.00 182.61 ? 46  PHE M CG    1 
ATOM   332  C CD1   . PHE A 1 41  ? 128.476 188.911 141.037 1.00 182.61 ? 46  PHE M CD1   1 
ATOM   333  C CD2   . PHE A 1 41  ? 129.433 190.313 142.703 1.00 182.61 ? 46  PHE M CD2   1 
ATOM   334  C CE1   . PHE A 1 41  ? 129.604 188.115 141.055 1.00 182.61 ? 46  PHE M CE1   1 
ATOM   335  C CE2   . PHE A 1 41  ? 130.561 189.522 142.725 1.00 182.61 ? 46  PHE M CE2   1 
ATOM   336  C CZ    . PHE A 1 41  ? 130.647 188.422 141.900 1.00 182.61 ? 46  PHE M CZ    1 
ATOM   337  N N     . VAL A 1 42  ? 125.362 192.515 139.482 1.00 185.33 ? 47  VAL M N     1 
ATOM   338  C CA    . VAL A 1 42  ? 124.077 193.072 139.098 1.00 185.33 ? 47  VAL M CA    1 
ATOM   339  C C     . VAL A 1 42  ? 123.233 191.986 138.459 1.00 185.33 ? 47  VAL M C     1 
ATOM   340  O O     . VAL A 1 42  ? 123.742 191.005 137.915 1.00 185.33 ? 47  VAL M O     1 
ATOM   341  C CB    . VAL A 1 42  ? 124.220 194.275 138.148 1.00 185.33 ? 47  VAL M CB    1 
ATOM   342  C CG1   . VAL A 1 42  ? 124.837 195.450 138.884 1.00 185.33 ? 47  VAL M CG1   1 
ATOM   343  C CG2   . VAL A 1 42  ? 125.070 193.888 136.951 1.00 185.33 ? 47  VAL M CG2   1 
ATOM   344  N N     . LYS A 1 43  ? 121.925 192.176 138.539 1.00 186.23 ? 48  LYS M N     1 
ATOM   345  C CA    . LYS A 1 43  ? 120.984 191.235 137.959 1.00 186.23 ? 48  LYS M CA    1 
ATOM   346  C C     . LYS A 1 43  ? 121.017 191.387 136.444 1.00 186.23 ? 48  LYS M C     1 
ATOM   347  O O     . LYS A 1 43  ? 120.851 192.492 135.921 1.00 186.23 ? 48  LYS M O     1 
ATOM   348  C CB    . LYS A 1 43  ? 119.590 191.489 138.524 1.00 186.23 ? 48  LYS M CB    1 
ATOM   349  C CG    . LYS A 1 43  ? 119.623 191.991 139.966 1.00 186.23 ? 48  LYS M CG    1 
ATOM   350  C CD    . LYS A 1 43  ? 118.245 192.033 140.596 1.00 186.23 ? 48  LYS M CD    1 
ATOM   351  C CE    . LYS A 1 43  ? 117.779 190.644 141.001 1.00 186.23 ? 48  LYS M CE    1 
ATOM   352  N NZ    . LYS A 1 43  ? 118.699 189.998 141.973 1.00 186.23 ? 48  LYS M NZ    1 
ATOM   353  N N     . ALA A 1 44  ? 121.266 190.288 135.742 1.00 187.60 ? 49  ALA M N     1 
ATOM   354  C CA    . ALA A 1 44  ? 121.386 190.337 134.292 1.00 187.60 ? 49  ALA M CA    1 
ATOM   355  C C     . ALA A 1 44  ? 121.076 188.958 133.729 1.00 187.60 ? 49  ALA M C     1 
ATOM   356  O O     . ALA A 1 44  ? 120.886 187.989 134.467 1.00 187.60 ? 49  ALA M O     1 
ATOM   357  C CB    . ALA A 1 44  ? 122.779 190.811 133.865 1.00 187.60 ? 49  ALA M CB    1 
ATOM   358  N N     . LYS A 1 45  ? 121.015 188.890 132.405 1.00 189.26 ? 50  LYS M N     1 
ATOM   359  C CA    . LYS A 1 45  ? 120.804 187.645 131.687 1.00 189.26 ? 50  LYS M CA    1 
ATOM   360  C C     . LYS A 1 45  ? 121.911 187.476 130.656 1.00 189.26 ? 50  LYS M C     1 
ATOM   361  O O     . LYS A 1 45  ? 122.429 188.463 130.126 1.00 189.26 ? 50  LYS M O     1 
ATOM   362  C CB    . LYS A 1 45  ? 119.429 187.626 131.012 1.00 189.26 ? 50  LYS M CB    1 
ATOM   363  C CG    . LYS A 1 45  ? 118.743 186.272 131.019 1.00 189.26 ? 50  LYS M CG    1 
ATOM   364  C CD    . LYS A 1 45  ? 117.383 186.334 130.333 1.00 189.26 ? 50  LYS M CD    1 
ATOM   365  C CE    . LYS A 1 45  ? 117.009 184.999 129.706 1.00 189.26 ? 50  LYS M CE    1 
ATOM   366  N NZ    . LYS A 1 45  ? 116.863 183.921 130.725 1.00 189.26 ? 50  LYS M NZ    1 
ATOM   367  N N     . ILE A 1 46  ? 122.295 186.229 130.399 1.00 191.23 ? 51  ILE M N     1 
ATOM   368  C CA    . ILE A 1 46  ? 123.304 185.910 129.393 1.00 191.23 ? 51  ILE M CA    1 
ATOM   369  C C     . ILE A 1 46  ? 122.609 185.341 128.166 1.00 191.23 ? 51  ILE M C     1 
ATOM   370  O O     . ILE A 1 46  ? 121.683 184.528 128.282 1.00 191.23 ? 51  ILE M O     1 
ATOM   371  C CB    . ILE A 1 46  ? 124.353 184.928 129.946 1.00 191.23 ? 51  ILE M CB    1 
ATOM   372  C CG1   . ILE A 1 46  ? 125.206 185.621 130.998 1.00 191.23 ? 51  ILE M CG1   1 
ATOM   373  C CG2   . ILE A 1 46  ? 125.251 184.413 128.834 1.00 191.23 ? 51  ILE M CG2   1 
ATOM   374  C CD1   . ILE A 1 46  ? 126.114 186.669 130.420 1.00 191.23 ? 51  ILE M CD1   1 
ATOM   375  N N     . VAL A 1 47  ? 123.046 185.775 126.982 1.00 193.49 ? 52  VAL M N     1 
ATOM   376  C CA    . VAL A 1 47  ? 122.449 185.264 125.753 1.00 193.49 ? 52  VAL M CA    1 
ATOM   377  C C     . VAL A 1 47  ? 122.976 183.868 125.440 1.00 193.49 ? 52  VAL M C     1 
ATOM   378  O O     . VAL A 1 47  ? 122.208 182.973 125.065 1.00 193.49 ? 52  VAL M O     1 
ATOM   379  C CB    . VAL A 1 47  ? 122.684 186.249 124.590 1.00 193.49 ? 52  VAL M CB    1 
ATOM   380  C CG1   . VAL A 1 47  ? 124.170 186.577 124.431 1.00 193.49 ? 52  VAL M CG1   1 
ATOM   381  C CG2   . VAL A 1 47  ? 122.090 185.703 123.292 1.00 193.49 ? 52  VAL M CG2   1 
ATOM   382  N N     . SER A 1 48  ? 124.279 183.650 125.603 1.00 195.36 ? 53  SER M N     1 
ATOM   383  C CA    . SER A 1 48  ? 124.879 182.355 125.302 1.00 195.36 ? 53  SER M CA    1 
ATOM   384  C C     . SER A 1 48  ? 126.286 182.310 125.880 1.00 195.36 ? 53  SER M C     1 
ATOM   385  O O     . SER A 1 48  ? 126.881 183.344 126.197 1.00 195.36 ? 53  SER M O     1 
ATOM   386  C CB    . SER A 1 48  ? 124.914 182.082 123.793 1.00 195.36 ? 53  SER M CB    1 
ATOM   387  O OG    . SER A 1 48  ? 125.739 180.969 123.498 1.00 195.36 ? 53  SER M OG    1 
ATOM   388  N N     . ARG A 1 49  ? 126.808 181.091 126.012 1.00 195.61 ? 54  ARG M N     1 
ATOM   389  C CA    . ARG A 1 49  ? 128.173 180.868 126.486 1.00 195.61 ? 54  ARG M CA    1 
ATOM   390  C C     . ARG A 1 49  ? 129.060 180.627 125.268 1.00 195.61 ? 54  ARG M C     1 
ATOM   391  O O     . ARG A 1 49  ? 129.466 179.504 124.964 1.00 195.61 ? 54  ARG M O     1 
ATOM   392  C CB    . ARG A 1 49  ? 128.217 179.704 127.469 1.00 195.61 ? 54  ARG M CB    1 
ATOM   393  C CG    . ARG A 1 49  ? 129.583 179.442 128.074 1.00 195.61 ? 54  ARG M CG    1 
ATOM   394  C CD    . ARG A 1 49  ? 129.502 178.377 129.154 1.00 195.61 ? 54  ARG M CD    1 
ATOM   395  N NE    . ARG A 1 49  ? 130.793 178.140 129.793 1.00 195.61 ? 54  ARG M NE    1 
ATOM   396  C CZ    . ARG A 1 49  ? 130.938 177.571 130.985 1.00 195.61 ? 54  ARG M CZ    1 
ATOM   397  N NH1   . ARG A 1 49  ? 129.870 177.185 131.670 1.00 195.61 ? 54  ARG M NH1   1 
ATOM   398  N NH2   . ARG A 1 49  ? 132.149 177.391 131.496 1.00 195.61 ? 54  ARG M NH2   1 
ATOM   399  N N     . GLU A 1 50  ? 129.366 181.718 124.563 1.00 197.03 ? 55  GLU M N     1 
ATOM   400  C CA    . GLU A 1 50  ? 130.174 181.651 123.346 1.00 197.03 ? 55  GLU M CA    1 
ATOM   401  C C     . GLU A 1 50  ? 131.647 181.636 123.742 1.00 197.03 ? 55  GLU M C     1 
ATOM   402  O O     . GLU A 1 50  ? 132.325 182.664 123.800 1.00 197.03 ? 55  GLU M O     1 
ATOM   403  C CB    . GLU A 1 50  ? 129.848 182.812 122.415 1.00 197.03 ? 55  GLU M CB    1 
ATOM   404  C CG    . GLU A 1 50  ? 128.361 183.051 122.194 1.00 197.03 ? 55  GLU M CG    1 
ATOM   405  C CD    . GLU A 1 50  ? 127.866 184.338 122.834 1.00 197.03 ? 55  GLU M CD    1 
ATOM   406  O OE1   . GLU A 1 50  ? 128.160 184.568 124.024 1.00 197.03 ? 55  GLU M OE1   1 
ATOM   407  O OE2   . GLU A 1 50  ? 127.178 185.119 122.144 1.00 197.03 ? 55  GLU M OE2   1 
ATOM   408  N N     . GLY A 1 51  ? 132.141 180.433 124.027 1.00 196.69 ? 56  GLY M N     1 
ATOM   409  C CA    . GLY A 1 51  ? 133.550 180.250 124.344 1.00 196.69 ? 56  GLY M CA    1 
ATOM   410  C C     . GLY A 1 51  ? 133.942 181.052 125.568 1.00 196.69 ? 56  GLY M C     1 
ATOM   411  O O     . GLY A 1 51  ? 133.425 180.844 126.672 1.00 196.69 ? 56  GLY M O     1 
ATOM   412  N N     . GLY A 1 52  ? 134.869 181.983 125.377 1.00 196.80 ? 57  GLY M N     1 
ATOM   413  C CA    . GLY A 1 52  ? 135.212 182.958 126.386 1.00 196.80 ? 57  GLY M CA    1 
ATOM   414  C C     . GLY A 1 52  ? 134.398 184.232 126.331 1.00 196.80 ? 57  GLY M C     1 
ATOM   415  O O     . GLY A 1 52  ? 134.707 185.185 127.053 1.00 196.80 ? 57  GLY M O     1 
ATOM   416  N N     . LYS A 1 53  ? 133.355 184.275 125.506 1.00 196.02 ? 58  LYS M N     1 
ATOM   417  C CA    . LYS A 1 53  ? 132.534 185.463 125.330 1.00 196.02 ? 58  LYS M CA    1 
ATOM   418  C C     . LYS A 1 53  ? 131.116 185.176 125.798 1.00 196.02 ? 58  LYS M C     1 
ATOM   419  O O     . LYS A 1 53  ? 130.502 184.192 125.373 1.00 196.02 ? 58  LYS M O     1 
ATOM   420  C CB    . LYS A 1 53  ? 132.521 185.918 123.867 1.00 196.02 ? 58  LYS M CB    1 
ATOM   421  C CG    . LYS A 1 53  ? 133.777 186.647 123.426 1.00 196.02 ? 58  LYS M CG    1 
ATOM   422  C CD    . LYS A 1 53  ? 133.783 188.084 123.916 1.00 196.02 ? 58  LYS M CD    1 
ATOM   423  C CE    . LYS A 1 53  ? 135.200 188.592 124.136 1.00 196.02 ? 58  LYS M CE    1 
ATOM   424  N NZ    . LYS A 1 53  ? 135.271 189.552 125.269 1.00 196.02 ? 58  LYS M NZ    1 
ATOM   425  N N     . VAL A 1 54  ? 130.612 186.027 126.691 1.00 194.88 ? 59  VAL M N     1 
ATOM   426  C CA    . VAL A 1 54  ? 129.215 186.038 127.093 1.00 194.88 ? 59  VAL M CA    1 
ATOM   427  C C     . VAL A 1 54  ? 128.748 187.485 127.033 1.00 194.88 ? 59  VAL M C     1 
ATOM   428  O O     . VAL A 1 54  ? 129.548 188.409 126.886 1.00 194.88 ? 59  VAL M O     1 
ATOM   429  C CB    . VAL A 1 54  ? 128.991 185.440 128.502 1.00 194.88 ? 59  VAL M CB    1 
ATOM   430  C CG1   . VAL A 1 54  ? 129.536 184.019 128.578 1.00 194.88 ? 59  VAL M CG1   1 
ATOM   431  C CG2   . VAL A 1 54  ? 129.636 186.317 129.558 1.00 194.88 ? 59  VAL M CG2   1 
ATOM   432  N N     . THR A 1 55  ? 127.436 187.682 127.120 1.00 193.58 ? 60  THR M N     1 
ATOM   433  C CA    . THR A 1 55  ? 126.857 189.022 127.061 1.00 193.58 ? 60  THR M CA    1 
ATOM   434  C C     . THR A 1 55  ? 125.778 189.135 128.125 1.00 193.58 ? 60  THR M C     1 
ATOM   435  O O     . THR A 1 55  ? 124.754 188.450 128.048 1.00 193.58 ? 60  THR M O     1 
ATOM   436  C CB    . THR A 1 55  ? 126.283 189.319 125.677 1.00 193.58 ? 60  THR M CB    1 
ATOM   437  O OG1   . THR A 1 55  ? 127.176 188.825 124.671 1.00 193.58 ? 60  THR M OG1   1 
ATOM   438  C CG2   . THR A 1 55  ? 126.109 190.814 125.493 1.00 193.58 ? 60  THR M CG2   1 
ATOM   439  N N     . ALA A 1 56  ? 126.000 189.996 129.110 1.00 191.88 ? 61  ALA M N     1 
ATOM   440  C CA    . ALA A 1 56  ? 125.059 190.184 130.206 1.00 191.88 ? 61  ALA M CA    1 
ATOM   441  C C     . ALA A 1 56  ? 124.118 191.331 129.868 1.00 191.88 ? 61  ALA M C     1 
ATOM   442  O O     . ALA A 1 56  ? 124.559 192.471 129.705 1.00 191.88 ? 61  ALA M O     1 
ATOM   443  C CB    . ALA A 1 56  ? 125.793 190.467 131.517 1.00 191.88 ? 61  ALA M CB    1 
ATOM   444  N N     . GLU A 1 57  ? 122.827 191.029 129.768 1.00 190.83 ? 62  GLU M N     1 
ATOM   445  C CA    . GLU A 1 57  ? 121.800 192.045 129.561 1.00 190.83 ? 62  GLU M CA    1 
ATOM   446  C C     . GLU A 1 57  ? 121.190 192.370 130.919 1.00 190.83 ? 62  GLU M C     1 
ATOM   447  O O     . GLU A 1 57  ? 120.342 191.631 131.427 1.00 190.83 ? 62  GLU M O     1 
ATOM   448  C CB    . GLU A 1 57  ? 120.741 191.573 128.570 1.00 190.83 ? 62  GLU M CB    1 
ATOM   449  C CG    . GLU A 1 57  ? 121.289 190.997 127.276 1.00 190.83 ? 62  GLU M CG    1 
ATOM   450  C CD    . GLU A 1 57  ? 121.501 189.502 127.343 1.00 190.83 ? 62  GLU M CD    1 
ATOM   451  O OE1   . GLU A 1 57  ? 122.418 188.996 126.661 1.00 190.83 ? 62  GLU M OE1   1 
ATOM   452  O OE2   . GLU A 1 57  ? 120.735 188.832 128.066 1.00 190.83 ? 62  GLU M OE2   1 
ATOM   453  N N     . THR A 1 58  ? 121.629 193.479 131.507 1.00 191.02 ? 63  THR M N     1 
ATOM   454  C CA    . THR A 1 58  ? 121.146 193.910 132.807 1.00 191.02 ? 63  THR M CA    1 
ATOM   455  C C     . THR A 1 58  ? 119.865 194.720 132.657 1.00 191.02 ? 63  THR M C     1 
ATOM   456  O O     . THR A 1 58  ? 119.340 194.915 131.559 1.00 191.02 ? 63  THR M O     1 
ATOM   457  C CB    . THR A 1 58  ? 122.199 194.743 133.529 1.00 191.02 ? 63  THR M CB    1 
ATOM   458  O OG1   . THR A 1 58  ? 121.738 195.043 134.852 1.00 191.02 ? 63  THR M OG1   1 
ATOM   459  C CG2   . THR A 1 58  ? 122.431 196.049 132.780 1.00 191.02 ? 63  THR M CG2   1 
ATOM   460  N N     . GLU A 1 59  ? 119.361 195.211 133.791 1.00 191.81 ? 64  GLU M N     1 
ATOM   461  C CA    . GLU A 1 59  ? 118.200 196.091 133.771 1.00 191.81 ? 64  GLU M CA    1 
ATOM   462  C C     . GLU A 1 59  ? 118.537 197.459 133.190 1.00 191.81 ? 64  GLU M C     1 
ATOM   463  O O     . GLU A 1 59  ? 117.683 198.086 132.553 1.00 191.81 ? 64  GLU M O     1 
ATOM   464  C CB    . GLU A 1 59  ? 117.631 196.226 135.186 1.00 191.81 ? 64  GLU M CB    1 
ATOM   465  C CG    . GLU A 1 59  ? 118.552 196.917 136.190 1.00 191.81 ? 64  GLU M CG    1 
ATOM   466  C CD    . GLU A 1 59  ? 119.546 195.957 136.821 1.00 191.81 ? 64  GLU M CD    1 
ATOM   467  O OE1   . GLU A 1 59  ? 119.755 194.868 136.256 1.00 191.81 ? 64  GLU M OE1   1 
ATOM   468  O OE2   . GLU A 1 59  ? 120.111 196.282 137.886 1.00 191.81 ? 64  GLU M OE2   1 
ATOM   469  N N     . TYR A 1 60  ? 119.765 197.933 133.384 1.00 191.93 ? 65  TYR M N     1 
ATOM   470  C CA    . TYR A 1 60  ? 120.169 199.256 132.926 1.00 191.93 ? 65  TYR M CA    1 
ATOM   471  C C     . TYR A 1 60  ? 120.369 199.337 131.419 1.00 191.93 ? 65  TYR M C     1 
ATOM   472  O O     . TYR A 1 60  ? 120.670 200.422 130.910 1.00 191.93 ? 65  TYR M O     1 
ATOM   473  C CB    . TYR A 1 60  ? 121.452 199.682 133.643 1.00 191.93 ? 65  TYR M CB    1 
ATOM   474  C CG    . TYR A 1 60  ? 121.249 199.935 135.116 1.00 191.93 ? 65  TYR M CG    1 
ATOM   475  C CD1   . TYR A 1 60  ? 120.811 201.167 135.574 1.00 191.93 ? 65  TYR M CD1   1 
ATOM   476  C CD2   . TYR A 1 60  ? 121.460 198.928 136.048 1.00 191.93 ? 65  TYR M CD2   1 
ATOM   477  C CE1   . TYR A 1 60  ? 120.615 201.401 136.920 1.00 191.93 ? 65  TYR M CE1   1 
ATOM   478  C CE2   . TYR A 1 60  ? 121.266 199.150 137.396 1.00 191.93 ? 65  TYR M CE2   1 
ATOM   479  C CZ    . TYR A 1 60  ? 120.841 200.388 137.827 1.00 191.93 ? 65  TYR M CZ    1 
ATOM   480  O OH    . TYR A 1 60  ? 120.642 200.619 139.170 1.00 191.93 ? 65  TYR M OH    1 
ATOM   481  N N     . GLY A 1 61  ? 120.215 198.230 130.697 1.00 191.62 ? 66  GLY M N     1 
ATOM   482  C CA    . GLY A 1 61  ? 120.418 198.227 129.265 1.00 191.62 ? 66  GLY M CA    1 
ATOM   483  C C     . GLY A 1 61  ? 121.835 197.949 128.818 1.00 191.62 ? 66  GLY M C     1 
ATOM   484  O O     . GLY A 1 61  ? 122.146 198.157 127.640 1.00 191.62 ? 66  GLY M O     1 
ATOM   485  N N     . LYS A 1 62  ? 122.702 197.492 129.715 1.00 190.51 ? 67  LYS M N     1 
ATOM   486  C CA    . LYS A 1 62  ? 124.091 197.253 129.360 1.00 190.51 ? 67  LYS M CA    1 
ATOM   487  C C     . LYS A 1 62  ? 124.289 195.811 128.910 1.00 190.51 ? 67  LYS M C     1 
ATOM   488  O O     . LYS A 1 62  ? 123.541 194.909 129.295 1.00 190.51 ? 67  LYS M O     1 
ATOM   489  C CB    . LYS A 1 62  ? 125.011 197.575 130.540 1.00 190.51 ? 67  LYS M CB    1 
ATOM   490  C CG    . LYS A 1 62  ? 124.590 198.784 131.371 1.00 190.51 ? 67  LYS M CG    1 
ATOM   491  C CD    . LYS A 1 62  ? 124.341 200.040 130.529 1.00 190.51 ? 67  LYS M CD    1 
ATOM   492  C CE    . LYS A 1 62  ? 125.519 200.389 129.625 1.00 190.51 ? 67  LYS M CE    1 
ATOM   493  N NZ    . LYS A 1 62  ? 125.178 201.489 128.686 1.00 190.51 ? 67  LYS M NZ    1 
ATOM   494  N N     . THR A 1 63  ? 125.312 195.607 128.078 1.00 192.35 ? 68  THR M N     1 
ATOM   495  C CA    . THR A 1 63  ? 125.598 194.333 127.420 1.00 192.35 ? 68  THR M CA    1 
ATOM   496  C C     . THR A 1 63  ? 127.074 193.968 127.561 1.00 192.35 ? 68  THR M C     1 
ATOM   497  O O     . THR A 1 63  ? 127.744 193.603 126.592 1.00 192.35 ? 68  THR M O     1 
ATOM   498  C CB    . THR A 1 63  ? 125.212 194.379 125.944 1.00 192.35 ? 68  THR M CB    1 
ATOM   499  O OG1   . THR A 1 63  ? 126.009 195.365 125.271 1.00 192.35 ? 68  THR M OG1   1 
ATOM   500  C CG2   . THR A 1 63  ? 123.735 194.719 125.775 1.00 192.35 ? 68  THR M CG2   1 
ATOM   501  N N     . VAL A 1 64  ? 127.605 194.054 128.782 1.00 193.21 ? 69  VAL M N     1 
ATOM   502  C CA    . VAL A 1 64  ? 129.028 193.806 128.987 1.00 193.21 ? 69  VAL M CA    1 
ATOM   503  C C     . VAL A 1 64  ? 129.320 192.309 128.946 1.00 193.21 ? 69  VAL M C     1 
ATOM   504  O O     . VAL A 1 64  ? 128.453 191.466 129.221 1.00 193.21 ? 69  VAL M O     1 
ATOM   505  C CB    . VAL A 1 64  ? 129.505 194.426 130.314 1.00 193.21 ? 69  VAL M CB    1 
ATOM   506  C CG1   . VAL A 1 64  ? 129.058 193.580 131.502 1.00 193.21 ? 69  VAL M CG1   1 
ATOM   507  C CG2   . VAL A 1 64  ? 131.019 194.609 130.308 1.00 193.21 ? 69  VAL M CG2   1 
ATOM   508  N N     . THR A 1 65  ? 130.557 191.976 128.583 1.00 194.20 ? 70  THR M N     1 
ATOM   509  C CA    . THR A 1 65  ? 131.067 190.612 128.619 1.00 194.20 ? 70  THR M CA    1 
ATOM   510  C C     . THR A 1 65  ? 131.923 190.409 129.864 1.00 194.20 ? 70  THR M C     1 
ATOM   511  O O     . THR A 1 65  ? 132.754 191.256 130.202 1.00 194.20 ? 70  THR M O     1 
ATOM   512  C CB    . THR A 1 65  ? 131.893 190.311 127.365 1.00 194.20 ? 70  THR M CB    1 
ATOM   513  O OG1   . THR A 1 65  ? 131.021 190.227 126.230 1.00 194.20 ? 70  THR M OG1   1 
ATOM   514  C CG2   . THR A 1 65  ? 132.654 188.998 127.511 1.00 194.20 ? 70  THR M CG2   1 
ATOM   515  N N     . VAL A 1 66  ? 131.717 189.284 130.543 1.00 192.67 ? 71  VAL M N     1 
ATOM   516  C CA    . VAL A 1 66  ? 132.526 188.912 131.696 1.00 192.67 ? 71  VAL M CA    1 
ATOM   517  C C     . VAL A 1 66  ? 133.107 187.527 131.456 1.00 192.67 ? 71  VAL M C     1 
ATOM   518  O O     . VAL A 1 66  ? 132.579 186.734 130.670 1.00 192.67 ? 71  VAL M O     1 
ATOM   519  C CB    . VAL A 1 66  ? 131.726 188.944 133.014 1.00 192.67 ? 71  VAL M CB    1 
ATOM   520  C CG1   . VAL A 1 66  ? 131.083 190.308 133.210 1.00 192.67 ? 71  VAL M CG1   1 
ATOM   521  C CG2   . VAL A 1 66  ? 130.689 187.840 133.029 1.00 192.67 ? 71  VAL M CG2   1 
ATOM   522  N N     . LYS A 1 67  ? 134.209 187.242 132.138 1.00 191.89 ? 72  LYS M N     1 
ATOM   523  C CA    . LYS A 1 67  ? 134.953 186.021 131.869 1.00 191.89 ? 72  LYS M CA    1 
ATOM   524  C C     . LYS A 1 67  ? 134.272 184.829 132.527 1.00 191.89 ? 72  LYS M C     1 
ATOM   525  O O     . LYS A 1 67  ? 133.656 184.952 133.589 1.00 191.89 ? 72  LYS M O     1 
ATOM   526  C CB    . LYS A 1 67  ? 136.392 186.158 132.361 1.00 191.89 ? 72  LYS M CB    1 
ATOM   527  C CG    . LYS A 1 67  ? 137.065 187.483 132.005 1.00 191.89 ? 72  LYS M CG    1 
ATOM   528  C CD    . LYS A 1 67  ? 136.738 187.953 130.591 1.00 191.89 ? 72  LYS M CD    1 
ATOM   529  C CE    . LYS A 1 67  ? 136.941 189.453 130.451 1.00 191.89 ? 72  LYS M CE    1 
ATOM   530  N NZ    . LYS A 1 67  ? 135.722 190.210 130.846 1.00 191.89 ? 72  LYS M NZ    1 
ATOM   531  N N     . GLU A 1 68  ? 134.390 183.664 131.887 1.00 192.68 ? 73  GLU M N     1 
ATOM   532  C CA    . GLU A 1 68  ? 133.716 182.457 132.351 1.00 192.68 ? 73  GLU M CA    1 
ATOM   533  C C     . GLU A 1 68  ? 134.230 181.965 133.697 1.00 192.68 ? 73  GLU M C     1 
ATOM   534  O O     . GLU A 1 68  ? 133.677 180.998 134.235 1.00 192.68 ? 73  GLU M O     1 
ATOM   535  C CB    . GLU A 1 68  ? 133.867 181.344 131.314 1.00 192.68 ? 73  GLU M CB    1 
ATOM   536  C CG    . GLU A 1 68  ? 135.304 181.029 130.947 1.00 192.68 ? 73  GLU M CG    1 
ATOM   537  C CD    . GLU A 1 68  ? 135.708 181.621 129.617 1.00 192.68 ? 73  GLU M CD    1 
ATOM   538  O OE1   . GLU A 1 68  ? 136.048 180.844 128.699 1.00 192.68 ? 73  GLU M OE1   1 
ATOM   539  O OE2   . GLU A 1 68  ? 135.698 182.864 129.494 1.00 192.68 ? 73  GLU M OE2   1 
ATOM   540  N N     . ASP A 1 69  ? 135.265 182.590 134.248 1.00 191.32 ? 74  ASP M N     1 
ATOM   541  C CA    . ASP A 1 69  ? 135.827 182.187 135.527 1.00 191.32 ? 74  ASP M CA    1 
ATOM   542  C C     . ASP A 1 69  ? 135.295 182.999 136.703 1.00 191.32 ? 74  ASP M C     1 
ATOM   543  O O     . ASP A 1 69  ? 135.713 182.758 137.839 1.00 191.32 ? 74  ASP M O     1 
ATOM   544  C CB    . ASP A 1 69  ? 137.357 182.283 135.475 1.00 191.32 ? 74  ASP M CB    1 
ATOM   545  C CG    . ASP A 1 69  ? 137.849 183.693 135.183 1.00 191.32 ? 74  ASP M CG    1 
ATOM   546  O OD1   . ASP A 1 69  ? 137.012 184.599 134.992 1.00 191.32 ? 74  ASP M OD1   1 
ATOM   547  O OD2   . ASP A 1 69  ? 139.080 183.894 135.137 1.00 191.32 ? 74  ASP M OD2   1 
ATOM   548  N N     . GLN A 1 70  ? 134.383 183.943 136.468 1.00 189.03 ? 75  GLN M N     1 
ATOM   549  C CA    . GLN A 1 70  ? 133.888 184.808 137.532 1.00 189.03 ? 75  GLN M CA    1 
ATOM   550  C C     . GLN A 1 70  ? 132.365 184.849 137.565 1.00 189.03 ? 75  GLN M C     1 
ATOM   551  O O     . GLN A 1 70  ? 131.776 185.835 138.010 1.00 189.03 ? 75  GLN M O     1 
ATOM   552  C CB    . GLN A 1 70  ? 134.455 186.221 137.391 1.00 189.03 ? 75  GLN M CB    1 
ATOM   553  C CG    . GLN A 1 70  ? 134.195 186.862 136.044 1.00 189.03 ? 75  GLN M CG    1 
ATOM   554  C CD    . GLN A 1 70  ? 134.750 188.266 135.959 1.00 189.03 ? 75  GLN M CD    1 
ATOM   555  O OE1   . GLN A 1 70  ? 135.221 188.816 136.952 1.00 189.03 ? 75  GLN M OE1   1 
ATOM   556  N NE2   . GLN A 1 70  ? 134.704 188.853 134.768 1.00 189.03 ? 75  GLN M NE2   1 
ATOM   557  N N     . VAL A 1 71  ? 131.713 183.791 137.107 1.00 188.28 ? 76  VAL M N     1 
ATOM   558  C CA    . VAL A 1 71  ? 130.258 183.722 137.083 1.00 188.28 ? 76  VAL M CA    1 
ATOM   559  C C     . VAL A 1 71  ? 129.791 182.625 138.030 1.00 188.28 ? 76  VAL M C     1 
ATOM   560  O O     . VAL A 1 71  ? 130.446 181.588 138.190 1.00 188.28 ? 76  VAL M O     1 
ATOM   561  C CB    . VAL A 1 71  ? 129.737 183.489 135.649 1.00 188.28 ? 76  VAL M CB    1 
ATOM   562  C CG1   . VAL A 1 71  ? 130.176 184.626 134.745 1.00 188.28 ? 76  VAL M CG1   1 
ATOM   563  C CG2   . VAL A 1 71  ? 130.244 182.165 135.108 1.00 188.28 ? 76  VAL M CG2   1 
ATOM   564  N N     . MET A 1 72  ? 128.648 182.863 138.666 1.00 186.01 ? 77  MET M N     1 
ATOM   565  C CA    . MET A 1 72  ? 128.119 181.933 139.651 1.00 186.01 ? 77  MET M CA    1 
ATOM   566  C C     . MET A 1 72  ? 126.608 182.091 139.708 1.00 186.01 ? 77  MET M C     1 
ATOM   567  O O     . MET A 1 72  ? 126.077 183.180 139.473 1.00 186.01 ? 77  MET M O     1 
ATOM   568  C CB    . MET A 1 72  ? 128.738 182.163 141.030 1.00 186.01 ? 77  MET M CB    1 
ATOM   569  C CG    . MET A 1 72  ? 128.484 183.550 141.600 1.00 186.01 ? 77  MET M CG    1 
ATOM   570  S SD    . MET A 1 72  ? 129.957 184.301 142.316 1.00 186.01 ? 77  MET M SD    1 
ATOM   571  C CE    . MET A 1 72  ? 130.951 184.574 140.851 1.00 186.01 ? 77  MET M CE    1 
ATOM   572  N N     . GLN A 1 73  ? 125.928 180.995 140.040 1.00 185.41 ? 78  GLN M N     1 
ATOM   573  C CA    . GLN A 1 73  ? 124.479 180.945 139.928 1.00 185.41 ? 78  GLN M CA    1 
ATOM   574  C C     . GLN A 1 73  ? 123.817 181.973 140.841 1.00 185.41 ? 78  GLN M C     1 
ATOM   575  O O     . GLN A 1 73  ? 124.413 182.484 141.788 1.00 185.41 ? 78  GLN M O     1 
ATOM   576  C CB    . GLN A 1 73  ? 123.957 179.547 140.265 1.00 185.41 ? 78  GLN M CB    1 
ATOM   577  C CG    . GLN A 1 73  ? 124.245 178.483 139.219 1.00 185.41 ? 78  GLN M CG    1 
ATOM   578  C CD    . GLN A 1 73  ? 125.679 178.019 139.246 1.00 185.41 ? 78  GLN M CD    1 
ATOM   579  O OE1   . GLN A 1 73  ? 126.411 178.162 138.268 1.00 185.41 ? 78  GLN M OE1   1 
ATOM   580  N NE2   . GLN A 1 73  ? 126.090 177.452 140.371 1.00 185.41 ? 78  GLN M NE2   1 
ATOM   581  N N     . GLN A 1 74  ? 122.556 182.264 140.543 1.00 185.38 ? 79  GLN M N     1 
ATOM   582  C CA    . GLN A 1 74  ? 121.725 183.112 141.382 1.00 185.38 ? 79  GLN M CA    1 
ATOM   583  C C     . GLN A 1 74  ? 120.801 182.234 142.216 1.00 185.38 ? 79  GLN M C     1 
ATOM   584  O O     . GLN A 1 74  ? 120.457 181.117 141.822 1.00 185.38 ? 79  GLN M O     1 
ATOM   585  C CB    . GLN A 1 74  ? 120.921 184.112 140.555 1.00 185.38 ? 79  GLN M CB    1 
ATOM   586  C CG    . GLN A 1 74  ? 120.124 185.113 141.387 1.00 185.38 ? 79  GLN M CG    1 
ATOM   587  C CD    . GLN A 1 74  ? 119.529 186.230 140.562 1.00 185.38 ? 79  GLN M CD    1 
ATOM   588  O OE1   . GLN A 1 74  ? 118.455 186.743 140.873 1.00 185.38 ? 79  GLN M OE1   1 
ATOM   589  N NE2   . GLN A 1 74  ? 120.229 186.620 139.503 1.00 185.38 ? 79  GLN M NE2   1 
ATOM   590  N N     . ASN A 1 75  ? 120.419 182.744 143.382 1.00 185.13 ? 80  ASN M N     1 
ATOM   591  C CA    . ASN A 1 75  ? 119.573 181.986 144.288 1.00 185.13 ? 80  ASN M CA    1 
ATOM   592  C C     . ASN A 1 75  ? 118.249 181.649 143.609 1.00 185.13 ? 80  ASN M C     1 
ATOM   593  O O     . ASN A 1 75  ? 117.657 182.501 142.938 1.00 185.13 ? 80  ASN M O     1 
ATOM   594  C CB    . ASN A 1 75  ? 119.318 182.773 145.571 1.00 185.13 ? 80  ASN M CB    1 
ATOM   595  C CG    . ASN A 1 75  ? 120.603 183.172 146.271 1.00 185.13 ? 80  ASN M CG    1 
ATOM   596  O OD1   . ASN A 1 75  ? 121.604 182.458 146.214 1.00 185.13 ? 80  ASN M OD1   1 
ATOM   597  N ND2   . ASN A 1 75  ? 120.576 184.317 146.948 1.00 185.13 ? 80  ASN M ND2   1 
ATOM   598  N N     . PRO A 1 76  ? 117.762 180.417 143.751 1.00 184.90 ? 81  PRO M N     1 
ATOM   599  C CA    . PRO A 1 76  ? 116.492 180.063 143.124 1.00 184.90 ? 81  PRO M CA    1 
ATOM   600  C C     . PRO A 1 76  ? 115.343 180.836 143.744 1.00 184.90 ? 81  PRO M C     1 
ATOM   601  O O     . PRO A 1 76  ? 115.433 181.298 144.896 1.00 184.90 ? 81  PRO M O     1 
ATOM   602  C CB    . PRO A 1 76  ? 116.368 178.554 143.404 1.00 184.90 ? 81  PRO M CB    1 
ATOM   603  C CG    . PRO A 1 76  ? 117.770 178.096 143.615 1.00 184.90 ? 81  PRO M CG    1 
ATOM   604  C CD    . PRO A 1 76  ? 118.455 179.242 144.295 1.00 184.90 ? 81  PRO M CD    1 
ATOM   605  N N     . PRO A 1 77  ? 114.236 181.007 143.014 1.00 184.41 ? 82  PRO M N     1 
ATOM   606  C CA    . PRO A 1 77  ? 113.104 181.755 143.578 1.00 184.41 ? 82  PRO M CA    1 
ATOM   607  C C     . PRO A 1 77  ? 112.420 181.027 144.715 1.00 184.41 ? 82  PRO M C     1 
ATOM   608  O O     . PRO A 1 77  ? 111.971 181.676 145.667 1.00 184.41 ? 82  PRO M O     1 
ATOM   609  C CB    . PRO A 1 77  ? 112.171 181.926 142.374 1.00 184.41 ? 82  PRO M CB    1 
ATOM   610  C CG    . PRO A 1 77  ? 112.474 180.749 141.507 1.00 184.41 ? 82  PRO M CG    1 
ATOM   611  C CD    . PRO A 1 77  ? 113.943 180.487 141.666 1.00 184.41 ? 82  PRO M CD    1 
ATOM   612  N N     . LYS A 1 78  ? 112.337 179.697 144.653 1.00 183.54 ? 83  LYS M N     1 
ATOM   613  C CA    . LYS A 1 78  ? 111.715 178.927 145.722 1.00 183.54 ? 83  LYS M CA    1 
ATOM   614  C C     . LYS A 1 78  ? 112.494 178.999 147.025 1.00 183.54 ? 83  LYS M C     1 
ATOM   615  O O     . LYS A 1 78  ? 112.058 178.417 148.023 1.00 183.54 ? 83  LYS M O     1 
ATOM   616  C CB    . LYS A 1 78  ? 111.562 177.468 145.295 1.00 183.54 ? 83  LYS M CB    1 
ATOM   617  C CG    . LYS A 1 78  ? 110.624 177.266 144.120 1.00 183.54 ? 83  LYS M CG    1 
ATOM   618  C CD    . LYS A 1 78  ? 109.209 177.716 144.449 1.00 183.54 ? 83  LYS M CD    1 
ATOM   619  C CE    . LYS A 1 78  ? 108.288 177.505 143.263 1.00 183.54 ? 83  LYS M CE    1 
ATOM   620  N NZ    . LYS A 1 78  ? 108.843 178.137 142.038 1.00 183.54 ? 83  LYS M NZ    1 
ATOM   621  N N     . PHE A 1 79  ? 113.636 179.683 147.036 1.00 182.79 ? 84  PHE M N     1 
ATOM   622  C CA    . PHE A 1 79  ? 114.443 179.804 148.241 1.00 182.79 ? 84  PHE M CA    1 
ATOM   623  C C     . PHE A 1 79  ? 114.973 181.220 148.422 1.00 182.79 ? 84  PHE M C     1 
ATOM   624  O O     . PHE A 1 79  ? 115.775 181.452 149.334 1.00 182.79 ? 84  PHE M O     1 
ATOM   625  C CB    . PHE A 1 79  ? 115.585 178.779 148.208 1.00 182.79 ? 84  PHE M CB    1 
ATOM   626  C CG    . PHE A 1 79  ? 115.118 177.384 147.893 1.00 182.79 ? 84  PHE M CG    1 
ATOM   627  C CD1   . PHE A 1 79  ? 114.771 176.510 148.907 1.00 182.79 ? 84  PHE M CD1   1 
ATOM   628  C CD2   . PHE A 1 79  ? 114.987 176.961 146.575 1.00 182.79 ? 84  PHE M CD2   1 
ATOM   629  C CE1   . PHE A 1 79  ? 114.322 175.232 148.617 1.00 182.79 ? 84  PHE M CE1   1 
ATOM   630  C CE2   . PHE A 1 79  ? 114.536 175.688 146.278 1.00 182.79 ? 84  PHE M CE2   1 
ATOM   631  C CZ    . PHE A 1 79  ? 114.204 174.821 147.301 1.00 182.79 ? 84  PHE M CZ    1 
ATOM   632  N N     . ASP A 1 80  ? 114.559 182.163 147.575 1.00 178.47 ? 85  ASP M N     1 
ATOM   633  C CA    . ASP A 1 80  ? 114.736 183.579 147.866 1.00 178.47 ? 85  ASP M CA    1 
ATOM   634  C C     . ASP A 1 80  ? 113.919 183.977 149.094 1.00 178.47 ? 85  ASP M C     1 
ATOM   635  O O     . ASP A 1 80  ? 113.061 183.232 149.573 1.00 178.47 ? 85  ASP M O     1 
ATOM   636  C CB    . ASP A 1 80  ? 114.314 184.429 146.667 1.00 178.47 ? 85  ASP M CB    1 
ATOM   637  C CG    . ASP A 1 80  ? 114.912 185.826 146.696 1.00 178.47 ? 85  ASP M CG    1 
ATOM   638  O OD1   . ASP A 1 80  ? 115.466 186.219 147.743 1.00 178.47 ? 85  ASP M OD1   1 
ATOM   639  O OD2   . ASP A 1 80  ? 114.820 186.536 145.673 1.00 178.47 ? 85  ASP M OD2   1 
ATOM   640  N N     . LYS A 1 81  ? 114.205 185.178 149.603 1.00 174.58 ? 86  LYS M N     1 
ATOM   641  C CA    . LYS A 1 81  ? 113.517 185.744 150.765 1.00 174.58 ? 86  LYS M CA    1 
ATOM   642  C C     . LYS A 1 81  ? 113.640 184.853 151.998 1.00 174.58 ? 86  LYS M C     1 
ATOM   643  O O     . LYS A 1 81  ? 112.816 184.926 152.912 1.00 174.58 ? 86  LYS M O     1 
ATOM   644  C CB    . LYS A 1 81  ? 112.040 186.013 150.457 1.00 174.58 ? 86  LYS M CB    1 
ATOM   645  C CG    . LYS A 1 81  ? 111.796 186.993 149.326 1.00 174.58 ? 86  LYS M CG    1 
ATOM   646  C CD    . LYS A 1 81  ? 112.067 188.409 149.774 1.00 174.58 ? 86  LYS M CD    1 
ATOM   647  C CE    . LYS A 1 81  ? 111.768 189.405 148.672 1.00 174.58 ? 86  LYS M CE    1 
ATOM   648  N NZ    . LYS A 1 81  ? 112.496 189.074 147.421 1.00 174.58 ? 86  LYS M NZ    1 
ATOM   649  N N     . ILE A 1 82  ? 114.672 184.010 152.039 1.00 173.15 ? 87  ILE M N     1 
ATOM   650  C CA    . ILE A 1 82  ? 114.822 183.059 153.132 1.00 173.15 ? 87  ILE M CA    1 
ATOM   651  C C     . ILE A 1 82  ? 115.202 183.798 154.408 1.00 173.15 ? 87  ILE M C     1 
ATOM   652  O O     . ILE A 1 82  ? 116.013 184.734 154.389 1.00 173.15 ? 87  ILE M O     1 
ATOM   653  C CB    . ILE A 1 82  ? 115.864 181.989 152.763 1.00 173.15 ? 87  ILE M CB    1 
ATOM   654  C CG1   . ILE A 1 82  ? 116.096 181.030 153.929 1.00 173.15 ? 87  ILE M CG1   1 
ATOM   655  C CG2   . ILE A 1 82  ? 117.162 182.638 152.320 1.00 173.15 ? 87  ILE M CG2   1 
ATOM   656  C CD1   . ILE A 1 82  ? 114.887 180.213 154.286 1.00 173.15 ? 87  ILE M CD1   1 
ATOM   657  N N     . GLU A 1 83  ? 114.605 183.388 155.530 1.00 170.64 ? 88  GLU M N     1 
ATOM   658  C CA    . GLU A 1 83  ? 114.887 184.059 156.795 1.00 170.64 ? 88  GLU M CA    1 
ATOM   659  C C     . GLU A 1 83  ? 116.310 183.781 157.261 1.00 170.64 ? 88  GLU M C     1 
ATOM   660  O O     . GLU A 1 83  ? 116.988 184.679 157.773 1.00 170.64 ? 88  GLU M O     1 
ATOM   661  C CB    . GLU A 1 83  ? 113.879 183.645 157.868 1.00 170.64 ? 88  GLU M CB    1 
ATOM   662  C CG    . GLU A 1 83  ? 113.910 182.180 158.259 1.00 170.64 ? 88  GLU M CG    1 
ATOM   663  C CD    . GLU A 1 83  ? 112.950 181.864 159.386 1.00 170.64 ? 88  GLU M CD    1 
ATOM   664  O OE1   . GLU A 1 83  ? 112.301 182.802 159.891 1.00 170.64 ? 88  GLU M OE1   1 
ATOM   665  O OE2   . GLU A 1 83  ? 112.837 180.678 159.763 1.00 170.64 ? 88  GLU M OE2   1 
ATOM   666  N N     . ASP A 1 84  ? 116.782 182.548 157.092 1.00 171.30 ? 89  ASP M N     1 
ATOM   667  C CA    . ASP A 1 84  ? 118.098 182.137 157.563 1.00 171.30 ? 89  ASP M CA    1 
ATOM   668  C C     . ASP A 1 84  ? 119.050 182.067 156.379 1.00 171.30 ? 89  ASP M C     1 
ATOM   669  O O     . ASP A 1 84  ? 118.929 181.173 155.534 1.00 171.30 ? 89  ASP M O     1 
ATOM   670  C CB    . ASP A 1 84  ? 118.033 180.787 158.276 1.00 171.30 ? 89  ASP M CB    1 
ATOM   671  C CG    . ASP A 1 84  ? 119.288 180.491 159.071 1.00 171.30 ? 89  ASP M CG    1 
ATOM   672  O OD1   . ASP A 1 84  ? 120.049 181.441 159.350 1.00 171.30 ? 89  ASP M OD1   1 
ATOM   673  O OD2   . ASP A 1 84  ? 119.513 179.313 159.418 1.00 171.30 ? 89  ASP M OD2   1 
ATOM   674  N N     . MET A 1 85  ? 120.005 182.998 156.332 1.00 171.49 ? 90  MET M N     1 
ATOM   675  C CA    . MET A 1 85  ? 120.967 183.009 155.240 1.00 171.49 ? 90  MET M CA    1 
ATOM   676  C C     . MET A 1 85  ? 121.754 181.711 155.184 1.00 171.49 ? 90  MET M C     1 
ATOM   677  O O     . MET A 1 85  ? 122.200 181.301 154.107 1.00 171.49 ? 90  MET M O     1 
ATOM   678  C CB    . MET A 1 85  ? 121.918 184.190 155.400 1.00 171.49 ? 90  MET M CB    1 
ATOM   679  C CG    . MET A 1 85  ? 121.243 185.488 155.789 1.00 171.49 ? 90  MET M CG    1 
ATOM   680  S SD    . MET A 1 85  ? 120.351 186.252 154.430 1.00 171.49 ? 90  MET M SD    1 
ATOM   681  C CE    . MET A 1 85  ? 120.362 187.957 154.969 1.00 171.49 ? 90  MET M CE    1 
ATOM   682  N N     . ALA A 1 86  ? 121.926 181.049 156.329 1.00 173.03 ? 91  ALA M N     1 
ATOM   683  C CA    . ALA A 1 86  ? 122.666 179.797 156.373 1.00 173.03 ? 91  ALA M CA    1 
ATOM   684  C C     . ALA A 1 86  ? 121.966 178.685 155.609 1.00 173.03 ? 91  ALA M C     1 
ATOM   685  O O     . ALA A 1 86  ? 122.631 177.753 155.144 1.00 173.03 ? 91  ALA M O     1 
ATOM   686  C CB    . ALA A 1 86  ? 122.883 179.370 157.824 1.00 173.03 ? 91  ALA M CB    1 
ATOM   687  N N     . MET A 1 87  ? 120.647 178.764 155.465 1.00 174.77 ? 92  MET M N     1 
ATOM   688  C CA    . MET A 1 87  ? 119.876 177.752 154.763 1.00 174.77 ? 92  MET M CA    1 
ATOM   689  C C     . MET A 1 87  ? 119.775 178.017 153.269 1.00 174.77 ? 92  MET M C     1 
ATOM   690  O O     . MET A 1 87  ? 119.089 177.271 152.567 1.00 174.77 ? 92  MET M O     1 
ATOM   691  C CB    . MET A 1 87  ? 118.474 177.654 155.374 1.00 174.77 ? 92  MET M CB    1 
ATOM   692  C CG    . MET A 1 87  ? 118.412 176.852 156.670 1.00 174.77 ? 92  MET M CG    1 
ATOM   693  S SD    . MET A 1 87  ? 119.367 175.321 156.660 1.00 174.77 ? 92  MET M SD    1 
ATOM   694  C CE    . MET A 1 87  ? 118.767 174.539 155.163 1.00 174.77 ? 92  MET M CE    1 
ATOM   695  N N     . LEU A 1 88  ? 120.440 179.055 152.772 1.00 176.39 ? 93  LEU M N     1 
ATOM   696  C CA    . LEU A 1 88  ? 120.416 179.344 151.346 1.00 176.39 ? 93  LEU M CA    1 
ATOM   697  C C     . LEU A 1 88  ? 120.961 178.161 150.560 1.00 176.39 ? 93  LEU M C     1 
ATOM   698  O O     . LEU A 1 88  ? 121.885 177.470 151.000 1.00 176.39 ? 93  LEU M O     1 
ATOM   699  C CB    . LEU A 1 88  ? 121.229 180.601 151.044 1.00 176.39 ? 93  LEU M CB    1 
ATOM   700  C CG    . LEU A 1 88  ? 120.450 181.914 151.023 1.00 176.39 ? 93  LEU M CG    1 
ATOM   701  C CD1   . LEU A 1 88  ? 121.382 183.088 151.235 1.00 176.39 ? 93  LEU M CD1   1 
ATOM   702  C CD2   . LEU A 1 88  ? 119.717 182.058 149.708 1.00 176.39 ? 93  LEU M CD2   1 
ATOM   703  N N     . THR A 1 89  ? 120.363 177.915 149.396 1.00 181.27 ? 94  THR M N     1 
ATOM   704  C CA    . THR A 1 89  ? 120.800 176.793 148.577 1.00 181.27 ? 94  THR M CA    1 
ATOM   705  C C     . THR A 1 89  ? 122.174 177.044 147.975 1.00 181.27 ? 94  THR M C     1 
ATOM   706  O O     . THR A 1 89  ? 122.916 176.092 147.722 1.00 181.27 ? 94  THR M O     1 
ATOM   707  C CB    . THR A 1 89  ? 119.781 176.511 147.476 1.00 181.27 ? 94  THR M CB    1 
ATOM   708  O OG1   . THR A 1 89  ? 119.640 177.673 146.652 1.00 181.27 ? 94  THR M OG1   1 
ATOM   709  C CG2   . THR A 1 89  ? 118.426 176.149 148.074 1.00 181.27 ? 94  THR M CG2   1 
ATOM   710  N N     . PHE A 1 90  ? 122.534 178.303 147.744 1.00 181.28 ? 95  PHE M N     1 
ATOM   711  C CA    . PHE A 1 90  ? 123.835 178.653 147.188 1.00 181.28 ? 95  PHE M CA    1 
ATOM   712  C C     . PHE A 1 90  ? 124.386 179.844 147.954 1.00 181.28 ? 95  PHE M C     1 
ATOM   713  O O     . PHE A 1 90  ? 123.790 180.925 147.937 1.00 181.28 ? 95  PHE M O     1 
ATOM   714  C CB    . PHE A 1 90  ? 123.731 178.960 145.692 1.00 181.28 ? 95  PHE M CB    1 
ATOM   715  C CG    . PHE A 1 90  ? 123.405 177.759 144.851 1.00 181.28 ? 95  PHE M CG    1 
ATOM   716  C CD1   . PHE A 1 90  ? 124.417 177.016 144.264 1.00 181.28 ? 95  PHE M CD1   1 
ATOM   717  C CD2   . PHE A 1 90  ? 122.091 177.370 144.652 1.00 181.28 ? 95  PHE M CD2   1 
ATOM   718  C CE1   . PHE A 1 90  ? 124.126 175.908 143.491 1.00 181.28 ? 95  PHE M CE1   1 
ATOM   719  C CE2   . PHE A 1 90  ? 121.790 176.265 143.882 1.00 181.28 ? 95  PHE M CE2   1 
ATOM   720  C CZ    . PHE A 1 90  ? 122.810 175.531 143.299 1.00 181.28 ? 95  PHE M CZ    1 
ATOM   721  N N     . LEU A 1 91  ? 125.521 179.644 148.618 1.00 175.78 ? 96  LEU M N     1 
ATOM   722  C CA    . LEU A 1 91  ? 126.104 180.636 149.519 1.00 175.78 ? 96  LEU M CA    1 
ATOM   723  C C     . LEU A 1 91  ? 127.216 181.377 148.787 1.00 175.78 ? 96  LEU M C     1 
ATOM   724  O O     . LEU A 1 91  ? 128.341 180.884 148.678 1.00 175.78 ? 96  LEU M O     1 
ATOM   725  C CB    . LEU A 1 91  ? 126.614 179.962 150.787 1.00 175.78 ? 96  LEU M CB    1 
ATOM   726  C CG    . LEU A 1 91  ? 125.488 179.435 151.676 1.00 175.78 ? 96  LEU M CG    1 
ATOM   727  C CD1   . LEU A 1 91  ? 125.943 178.236 152.458 1.00 175.78 ? 96  LEU M CD1   1 
ATOM   728  C CD2   . LEU A 1 91  ? 125.008 180.520 152.618 1.00 175.78 ? 96  LEU M CD2   1 
ATOM   729  N N     . HIS A 1 92  ? 126.895 182.564 148.291 1.00 177.91 ? 97  HIS M N     1 
ATOM   730  C CA    . HIS A 1 92  ? 127.838 183.433 147.608 1.00 177.91 ? 97  HIS M CA    1 
ATOM   731  C C     . HIS A 1 92  ? 127.935 184.747 148.364 1.00 177.91 ? 97  HIS M C     1 
ATOM   732  O O     . HIS A 1 92  ? 127.161 185.018 149.285 1.00 177.91 ? 97  HIS M O     1 
ATOM   733  C CB    . HIS A 1 92  ? 127.410 183.693 146.159 1.00 177.91 ? 97  HIS M CB    1 
ATOM   734  C CG    . HIS A 1 92  ? 127.096 182.451 145.388 1.00 177.91 ? 97  HIS M CG    1 
ATOM   735  N ND1   . HIS A 1 92  ? 127.923 181.959 144.402 1.00 177.91 ? 97  HIS M ND1   1 
ATOM   736  C CD2   . HIS A 1 92  ? 126.045 181.600 145.457 1.00 177.91 ? 97  HIS M CD2   1 
ATOM   737  C CE1   . HIS A 1 92  ? 127.395 180.858 143.898 1.00 177.91 ? 97  HIS M CE1   1 
ATOM   738  N NE2   . HIS A 1 92  ? 126.256 180.618 144.521 1.00 177.91 ? 97  HIS M NE2   1 
ATOM   739  N N     . GLU A 1 93  ? 128.903 185.578 147.964 1.00 174.03 ? 98  GLU M N     1 
ATOM   740  C CA    . GLU A 1 93  ? 129.008 186.901 148.581 1.00 174.03 ? 98  GLU M CA    1 
ATOM   741  C C     . GLU A 1 93  ? 127.855 187.797 148.150 1.00 174.03 ? 98  GLU M C     1 
ATOM   742  O O     . GLU A 1 93  ? 127.050 188.197 149.011 1.00 174.03 ? 98  GLU M O     1 
ATOM   743  C CB    . GLU A 1 93  ? 130.382 187.514 148.290 1.00 174.03 ? 98  GLU M CB    1 
ATOM   744  C CG    . GLU A 1 93  ? 130.715 188.736 149.137 1.00 174.03 ? 98  GLU M CG    1 
ATOM   745  C CD    . GLU A 1 93  ? 130.218 190.037 148.530 1.00 174.03 ? 98  GLU M CD    1 
ATOM   746  O OE1   . GLU A 1 93  ? 129.767 190.027 147.367 1.00 174.03 ? 98  GLU M OE1   1 
ATOM   747  O OE2   . GLU A 1 93  ? 130.277 191.076 149.218 1.00 174.03 ? 98  GLU M OE2   1 
ATOM   748  N N     . PRO A 1 94  ? 127.684 188.130 146.864 1.00 176.87 ? 99  PRO M N     1 
ATOM   749  C CA    . PRO A 1 94  ? 126.589 189.037 146.497 1.00 176.87 ? 99  PRO M CA    1 
ATOM   750  C C     . PRO A 1 94  ? 125.218 188.401 146.632 1.00 176.87 ? 99  PRO M C     1 
ATOM   751  O O     . PRO A 1 94  ? 124.212 189.123 146.591 1.00 176.87 ? 99  PRO M O     1 
ATOM   752  C CB    . PRO A 1 94  ? 126.902 189.381 145.040 1.00 176.87 ? 99  PRO M CB    1 
ATOM   753  C CG    . PRO A 1 94  ? 127.537 188.144 144.527 1.00 176.87 ? 99  PRO M CG    1 
ATOM   754  C CD    . PRO A 1 94  ? 128.360 187.599 145.662 1.00 176.87 ? 99  PRO M CD    1 
ATOM   755  N N     . ALA A 1 95  ? 125.154 187.077 146.796 1.00 177.74 ? 100 ALA M N     1 
ATOM   756  C CA    . ALA A 1 95  ? 123.875 186.413 147.011 1.00 177.74 ? 100 ALA M CA    1 
ATOM   757  C C     . ALA A 1 95  ? 123.184 186.957 148.253 1.00 177.74 ? 100 ALA M C     1 
ATOM   758  O O     . ALA A 1 95  ? 122.019 187.373 148.202 1.00 177.74 ? 100 ALA M O     1 
ATOM   759  C CB    . ALA A 1 95  ? 124.084 184.903 147.129 1.00 177.74 ? 100 ALA M CB    1 
ATOM   760  N N     . VAL A 1 96  ? 123.897 186.978 149.378 1.00 175.06 ? 101 VAL M N     1 
ATOM   761  C CA    . VAL A 1 96  ? 123.313 187.483 150.614 1.00 175.06 ? 101 VAL M CA    1 
ATOM   762  C C     . VAL A 1 96  ? 123.069 188.984 150.514 1.00 175.06 ? 101 VAL M C     1 
ATOM   763  O O     . VAL A 1 96  ? 122.114 189.510 151.101 1.00 175.06 ? 101 VAL M O     1 
ATOM   764  C CB    . VAL A 1 96  ? 124.211 187.124 151.809 1.00 175.06 ? 101 VAL M CB    1 
ATOM   765  C CG1   . VAL A 1 96  ? 123.450 187.289 153.105 1.00 175.06 ? 101 VAL M CG1   1 
ATOM   766  C CG2   . VAL A 1 96  ? 124.729 185.700 151.668 1.00 175.06 ? 101 VAL M CG2   1 
ATOM   767  N N     . LEU A 1 97  ? 123.919 189.696 149.768 1.00 174.01 ? 102 LEU M N     1 
ATOM   768  C CA    . LEU A 1 97  ? 123.687 191.121 149.556 1.00 174.01 ? 102 LEU M CA    1 
ATOM   769  C C     . LEU A 1 97  ? 122.332 191.355 148.908 1.00 174.01 ? 102 LEU M C     1 
ATOM   770  O O     . LEU A 1 97  ? 121.536 192.169 149.382 1.00 174.01 ? 102 LEU M O     1 
ATOM   771  C CB    . LEU A 1 97  ? 124.798 191.729 148.700 1.00 174.01 ? 102 LEU M CB    1 
ATOM   772  C CG    . LEU A 1 97  ? 124.702 193.246 148.470 1.00 174.01 ? 102 LEU M CG    1 
ATOM   773  C CD1   . LEU A 1 97  ? 126.063 193.899 148.548 1.00 174.01 ? 102 LEU M CD1   1 
ATOM   774  C CD2   . LEU A 1 97  ? 124.068 193.565 147.130 1.00 174.01 ? 102 LEU M CD2   1 
ATOM   775  N N     . TYR A 1 98  ? 122.047 190.641 147.821 1.00 177.36 ? 103 TYR M N     1 
ATOM   776  C CA    . TYR A 1 98  ? 120.761 190.836 147.160 1.00 177.36 ? 103 TYR M CA    1 
ATOM   777  C C     . TYR A 1 98  ? 119.613 190.289 147.994 1.00 177.36 ? 103 TYR M C     1 
ATOM   778  O O     . TYR A 1 98  ? 118.503 190.828 147.936 1.00 177.36 ? 103 TYR M O     1 
ATOM   779  C CB    . TYR A 1 98  ? 120.775 190.205 145.772 1.00 177.36 ? 103 TYR M CB    1 
ATOM   780  C CG    . TYR A 1 98  ? 121.380 191.125 144.748 1.00 177.36 ? 103 TYR M CG    1 
ATOM   781  C CD1   . TYR A 1 98  ? 120.625 192.133 144.167 1.00 177.36 ? 103 TYR M CD1   1 
ATOM   782  C CD2   . TYR A 1 98  ? 122.709 191.000 144.374 1.00 177.36 ? 103 TYR M CD2   1 
ATOM   783  C CE1   . TYR A 1 98  ? 121.174 192.987 143.238 1.00 177.36 ? 103 TYR M CE1   1 
ATOM   784  C CE2   . TYR A 1 98  ? 123.265 191.846 143.444 1.00 177.36 ? 103 TYR M CE2   1 
ATOM   785  C CZ    . TYR A 1 98  ? 122.493 192.837 142.878 1.00 177.36 ? 103 TYR M CZ    1 
ATOM   786  O OH    . TYR A 1 98  ? 123.042 193.688 141.951 1.00 177.36 ? 103 TYR M OH    1 
ATOM   787  N N     . ASN A 1 99  ? 119.859 189.239 148.780 1.00 173.85 ? 104 ASN M N     1 
ATOM   788  C CA    . ASN A 1 99  ? 118.844 188.753 149.709 1.00 173.85 ? 104 ASN M CA    1 
ATOM   789  C C     . ASN A 1 99  ? 118.400 189.865 150.652 1.00 173.85 ? 104 ASN M C     1 
ATOM   790  O O     . ASN A 1 99  ? 117.214 190.207 150.722 1.00 173.85 ? 104 ASN M O     1 
ATOM   791  C CB    . ASN A 1 99  ? 119.393 187.562 150.496 1.00 173.85 ? 104 ASN M CB    1 
ATOM   792  C CG    . ASN A 1 99  ? 118.408 187.030 151.518 1.00 173.85 ? 104 ASN M CG    1 
ATOM   793  O OD1   . ASN A 1 99  ? 118.185 187.640 152.560 1.00 173.85 ? 104 ASN M OD1   1 
ATOM   794  N ND2   . ASN A 1 99  ? 117.833 185.871 151.234 1.00 173.85 ? 104 ASN M ND2   1 
ATOM   795  N N     . LEU A 1 100 ? 119.351 190.456 151.375 1.00 172.75 ? 105 LEU M N     1 
ATOM   796  C CA    . LEU A 1 100 ? 119.009 191.548 152.279 1.00 172.75 ? 105 LEU M CA    1 
ATOM   797  C C     . LEU A 1 100 ? 118.490 192.763 151.519 1.00 172.75 ? 105 LEU M C     1 
ATOM   798  O O     . LEU A 1 100 ? 117.683 193.529 152.054 1.00 172.75 ? 105 LEU M O     1 
ATOM   799  C CB    . LEU A 1 100 ? 120.220 191.916 153.139 1.00 172.75 ? 105 LEU M CB    1 
ATOM   800  C CG    . LEU A 1 100 ? 121.491 192.404 152.441 1.00 172.75 ? 105 LEU M CG    1 
ATOM   801  C CD1   . LEU A 1 100 ? 121.483 193.910 152.215 1.00 172.75 ? 105 LEU M CD1   1 
ATOM   802  C CD2   . LEU A 1 100 ? 122.730 191.979 153.208 1.00 172.75 ? 105 LEU M CD2   1 
ATOM   803  N N     . LYS A 1 101 ? 118.928 192.949 150.273 1.00 172.19 ? 106 LYS M N     1 
ATOM   804  C CA    . LYS A 1 101 ? 118.441 194.066 149.476 1.00 172.19 ? 106 LYS M CA    1 
ATOM   805  C C     . LYS A 1 101 ? 116.946 193.941 149.226 1.00 172.19 ? 106 LYS M C     1 
ATOM   806  O O     . LYS A 1 101 ? 116.176 194.871 149.491 1.00 172.19 ? 106 LYS M O     1 
ATOM   807  C CB    . LYS A 1 101 ? 119.209 194.131 148.158 1.00 172.19 ? 106 LYS M CB    1 
ATOM   808  C CG    . LYS A 1 101 ? 118.810 195.274 147.252 1.00 172.19 ? 106 LYS M CG    1 
ATOM   809  C CD    . LYS A 1 101 ? 119.628 195.240 145.981 1.00 172.19 ? 106 LYS M CD    1 
ATOM   810  C CE    . LYS A 1 101 ? 119.452 196.512 145.181 1.00 172.19 ? 106 LYS M CE    1 
ATOM   811  N NZ    . LYS A 1 101 ? 120.316 196.512 143.970 1.00 172.19 ? 106 LYS M NZ    1 
ATOM   812  N N     . ASP A 1 102 ? 116.515 192.788 148.714 1.00 174.19 ? 107 ASP M N     1 
ATOM   813  C CA    . ASP A 1 102 ? 115.088 192.584 148.501 1.00 174.19 ? 107 ASP M CA    1 
ATOM   814  C C     . ASP A 1 102 ? 114.326 192.542 149.819 1.00 174.19 ? 107 ASP M C     1 
ATOM   815  O O     . ASP A 1 102 ? 113.144 192.898 149.860 1.00 174.19 ? 107 ASP M O     1 
ATOM   816  C CB    . ASP A 1 102 ? 114.835 191.308 147.697 1.00 174.19 ? 107 ASP M CB    1 
ATOM   817  C CG    . ASP A 1 102 ? 115.318 190.061 148.405 1.00 174.19 ? 107 ASP M CG    1 
ATOM   818  O OD1   . ASP A 1 102 ? 116.226 189.393 147.874 1.00 174.19 ? 107 ASP M OD1   1 
ATOM   819  O OD2   . ASP A 1 102 ? 114.798 189.743 149.493 1.00 174.19 ? 107 ASP M OD2   1 
ATOM   820  N N     . ARG A 1 103 ? 114.976 192.125 150.907 1.00 170.91 ? 108 ARG M N     1 
ATOM   821  C CA    . ARG A 1 103 ? 114.268 192.071 152.180 1.00 170.91 ? 108 ARG M CA    1 
ATOM   822  C C     . ARG A 1 103 ? 114.041 193.466 152.754 1.00 170.91 ? 108 ARG M C     1 
ATOM   823  O O     . ARG A 1 103 ? 113.022 193.713 153.409 1.00 170.91 ? 108 ARG M O     1 
ATOM   824  C CB    . ARG A 1 103 ? 115.024 191.183 153.162 1.00 170.91 ? 108 ARG M CB    1 
ATOM   825  C CG    . ARG A 1 103 ? 114.877 189.702 152.857 1.00 170.91 ? 108 ARG M CG    1 
ATOM   826  C CD    . ARG A 1 103 ? 115.383 188.867 154.002 1.00 170.91 ? 108 ARG M CD    1 
ATOM   827  N NE    . ARG A 1 103 ? 114.540 189.027 155.179 1.00 170.91 ? 108 ARG M NE    1 
ATOM   828  C CZ    . ARG A 1 103 ? 113.837 188.046 155.727 1.00 170.91 ? 108 ARG M CZ    1 
ATOM   829  N NH1   . ARG A 1 103 ? 113.885 186.828 155.211 1.00 170.91 ? 108 ARG M NH1   1 
ATOM   830  N NH2   . ARG A 1 103 ? 113.092 188.282 156.795 1.00 170.91 ? 108 ARG M NH2   1 
ATOM   831  N N     . TYR A 1 104 ? 114.974 194.391 152.525 1.00 169.97 ? 109 TYR M N     1 
ATOM   832  C CA    . TYR A 1 104 ? 114.765 195.763 152.977 1.00 169.97 ? 109 TYR M CA    1 
ATOM   833  C C     . TYR A 1 104 ? 113.900 196.566 152.011 1.00 169.97 ? 109 TYR M C     1 
ATOM   834  O O     . TYR A 1 104 ? 113.233 197.519 152.433 1.00 169.97 ? 109 TYR M O     1 
ATOM   835  C CB    . TYR A 1 104 ? 116.103 196.471 153.193 1.00 169.97 ? 109 TYR M CB    1 
ATOM   836  C CG    . TYR A 1 104 ? 115.947 197.857 153.769 1.00 169.97 ? 109 TYR M CG    1 
ATOM   837  C CD1   . TYR A 1 104 ? 115.476 198.042 155.057 1.00 169.97 ? 109 TYR M CD1   1 
ATOM   838  C CD2   . TYR A 1 104 ? 116.253 198.980 153.018 1.00 169.97 ? 109 TYR M CD2   1 
ATOM   839  C CE1   . TYR A 1 104 ? 115.327 199.309 155.586 1.00 169.97 ? 109 TYR M CE1   1 
ATOM   840  C CE2   . TYR A 1 104 ? 116.107 200.252 153.535 1.00 169.97 ? 109 TYR M CE2   1 
ATOM   841  C CZ    . TYR A 1 104 ? 115.642 200.412 154.820 1.00 169.97 ? 109 TYR M CZ    1 
ATOM   842  O OH    . TYR A 1 104 ? 115.492 201.676 155.348 1.00 169.97 ? 109 TYR M OH    1 
ATOM   843  N N     . GLY A 1 105 ? 113.898 196.213 150.724 1.00 171.03 ? 110 GLY M N     1 
ATOM   844  C CA    . GLY A 1 105 ? 112.926 196.803 149.816 1.00 171.03 ? 110 GLY M CA    1 
ATOM   845  C C     . GLY A 1 105 ? 111.509 196.375 150.149 1.00 171.03 ? 110 GLY M C     1 
ATOM   846  O O     . GLY A 1 105 ? 110.589 197.196 150.180 1.00 171.03 ? 110 GLY M O     1 
ATOM   847  N N     . SER A 1 106 ? 111.320 195.086 150.416 1.00 171.71 ? 111 SER M N     1 
ATOM   848  C CA    . SER A 1 106 ? 110.085 194.544 150.959 1.00 171.71 ? 111 SER M CA    1 
ATOM   849  C C     . SER A 1 106 ? 109.884 194.897 152.425 1.00 171.71 ? 111 SER M C     1 
ATOM   850  O O     . SER A 1 106 ? 108.874 194.495 153.012 1.00 171.71 ? 111 SER M O     1 
ATOM   851  C CB    . SER A 1 106 ? 110.086 193.030 150.785 1.00 171.71 ? 111 SER M CB    1 
ATOM   852  O OG    . SER A 1 106 ? 111.066 192.461 151.629 1.00 171.71 ? 111 SER M OG    1 
ATOM   853  N N     . TRP A 1 107 ? 110.828 195.623 153.024 1.00 171.46 ? 112 TRP M N     1 
ATOM   854  C CA    . TRP A 1 107 ? 110.679 196.177 154.368 1.00 171.46 ? 112 TRP M CA    1 
ATOM   855  C C     . TRP A 1 107 ? 110.556 195.081 155.424 1.00 171.46 ? 112 TRP M C     1 
ATOM   856  O O     . TRP A 1 107 ? 109.653 195.089 156.260 1.00 171.46 ? 112 TRP M O     1 
ATOM   857  C CB    . TRP A 1 107 ? 109.498 197.146 154.425 1.00 171.46 ? 112 TRP M CB    1 
ATOM   858  C CG    . TRP A 1 107 ? 109.867 198.514 153.961 1.00 171.46 ? 112 TRP M CG    1 
ATOM   859  C CD1   . TRP A 1 107 ? 111.078 199.124 154.106 1.00 171.46 ? 112 TRP M CD1   1 
ATOM   860  C CD2   . TRP A 1 107 ? 109.029 199.446 153.269 1.00 171.46 ? 112 TRP M CD2   1 
ATOM   861  N NE1   . TRP A 1 107 ? 111.044 200.383 153.555 1.00 171.46 ? 112 TRP M NE1   1 
ATOM   862  C CE2   . TRP A 1 107 ? 109.798 200.603 153.033 1.00 171.46 ? 112 TRP M CE2   1 
ATOM   863  C CE3   . TRP A 1 107 ? 107.704 199.417 152.830 1.00 171.46 ? 112 TRP M CE3   1 
ATOM   864  C CZ2   . TRP A 1 107 ? 109.286 201.717 152.379 1.00 171.46 ? 112 TRP M CZ2   1 
ATOM   865  C CZ3   . TRP A 1 107 ? 107.198 200.525 152.183 1.00 171.46 ? 112 TRP M CZ3   1 
ATOM   866  C CH2   . TRP A 1 107 ? 107.987 201.660 151.962 1.00 171.46 ? 112 TRP M CH2   1 
ATOM   867  N N     . MET A 1 108 ? 111.480 194.126 155.379 1.00 170.81 ? 113 MET M N     1 
ATOM   868  C CA    . MET A 1 108 ? 111.706 193.199 156.481 1.00 170.81 ? 113 MET M CA    1 
ATOM   869  C C     . MET A 1 108 ? 113.080 193.517 157.056 1.00 170.81 ? 113 MET M C     1 
ATOM   870  O O     . MET A 1 108 ? 114.101 193.314 156.390 1.00 170.81 ? 113 MET M O     1 
ATOM   871  C CB    . MET A 1 108 ? 111.602 191.740 156.039 1.00 170.81 ? 113 MET M CB    1 
ATOM   872  C CG    . MET A 1 108 ? 110.166 191.247 155.920 1.00 170.81 ? 113 MET M CG    1 
ATOM   873  S SD    . MET A 1 108 ? 109.369 191.683 154.367 1.00 170.81 ? 113 MET M SD    1 
ATOM   874  C CE    . MET A 1 108 ? 109.897 190.308 153.351 1.00 170.81 ? 113 MET M CE    1 
ATOM   875  N N     . ILE A 1 109 ? 113.097 194.038 158.282 1.00 165.10 ? 114 ILE M N     1 
ATOM   876  C CA    . ILE A 1 109 ? 114.341 194.514 158.880 1.00 165.10 ? 114 ILE M CA    1 
ATOM   877  C C     . ILE A 1 109 ? 115.221 193.341 159.290 1.00 165.10 ? 114 ILE M C     1 
ATOM   878  O O     . ILE A 1 109 ? 116.327 193.157 158.770 1.00 165.10 ? 114 ILE M O     1 
ATOM   879  C CB    . ILE A 1 109 ? 114.037 195.430 160.078 1.00 165.10 ? 114 ILE M CB    1 
ATOM   880  C CG1   . ILE A 1 109 ? 113.445 196.756 159.592 1.00 165.10 ? 114 ILE M CG1   1 
ATOM   881  C CG2   . ILE A 1 109 ? 115.273 195.645 160.916 1.00 165.10 ? 114 ILE M CG2   1 
ATOM   882  C CD1   . ILE A 1 109 ? 114.171 197.363 158.398 1.00 165.10 ? 114 ILE M CD1   1 
ATOM   883  N N     . TYR A 1 110 ? 114.734 192.524 160.212 1.00 163.83 ? 115 TYR M N     1 
ATOM   884  C CA    . TYR A 1 110 ? 115.558 191.526 160.871 1.00 163.83 ? 115 TYR M CA    1 
ATOM   885  C C     . TYR A 1 110 ? 115.689 190.286 160.003 1.00 163.83 ? 115 TYR M C     1 
ATOM   886  O O     . TYR A 1 110 ? 114.755 189.909 159.291 1.00 163.83 ? 115 TYR M O     1 
ATOM   887  C CB    . TYR A 1 110 ? 114.961 191.170 162.231 1.00 163.83 ? 115 TYR M CB    1 
ATOM   888  C CG    . TYR A 1 110 ? 114.824 192.368 163.140 1.00 163.83 ? 115 TYR M CG    1 
ATOM   889  C CD1   . TYR A 1 110 ? 113.759 193.248 163.010 1.00 163.83 ? 115 TYR M CD1   1 
ATOM   890  C CD2   . TYR A 1 110 ? 115.772 192.631 164.116 1.00 163.83 ? 115 TYR M CD2   1 
ATOM   891  C CE1   . TYR A 1 110 ? 113.640 194.349 163.828 1.00 163.83 ? 115 TYR M CE1   1 
ATOM   892  C CE2   . TYR A 1 110 ? 115.656 193.728 164.942 1.00 163.83 ? 115 TYR M CE2   1 
ATOM   893  C CZ    . TYR A 1 110 ? 114.588 194.581 164.795 1.00 163.83 ? 115 TYR M CZ    1 
ATOM   894  O OH    . TYR A 1 110 ? 114.473 195.675 165.619 1.00 163.83 ? 115 TYR M OH    1 
ATOM   895  N N     . THR A 1 111 ? 116.866 189.667 160.052 1.00 165.27 ? 116 THR M N     1 
ATOM   896  C CA    . THR A 1 111 ? 117.142 188.474 159.266 1.00 165.27 ? 116 THR M CA    1 
ATOM   897  C C     . THR A 1 111 ? 118.118 187.579 160.015 1.00 165.27 ? 116 THR M C     1 
ATOM   898  O O     . THR A 1 111 ? 119.155 188.044 160.493 1.00 165.27 ? 116 THR M O     1 
ATOM   899  C CB    . THR A 1 111 ? 117.682 188.842 157.872 1.00 165.27 ? 116 THR M CB    1 
ATOM   900  O OG1   . THR A 1 111 ? 117.916 187.650 157.111 1.00 165.27 ? 116 THR M OG1   1 
ATOM   901  C CG2   . THR A 1 111 ? 118.953 189.670 157.960 1.00 165.27 ? 116 THR M CG2   1 
ATOM   902  N N     . TYR A 1 112 ? 117.763 186.305 160.143 1.00 165.70 ? 117 TYR M N     1 
ATOM   903  C CA    . TYR A 1 112 ? 118.651 185.324 160.748 1.00 165.70 ? 117 TYR M CA    1 
ATOM   904  C C     . TYR A 1 112 ? 119.738 184.928 159.759 1.00 165.70 ? 117 TYR M C     1 
ATOM   905  O O     . TYR A 1 112 ? 119.493 184.810 158.557 1.00 165.70 ? 117 TYR M O     1 
ATOM   906  C CB    . TYR A 1 112 ? 117.872 184.082 161.181 1.00 165.70 ? 117 TYR M CB    1 
ATOM   907  C CG    . TYR A 1 112 ? 117.155 184.206 162.507 1.00 165.70 ? 117 TYR M CG    1 
ATOM   908  C CD1   . TYR A 1 112 ? 117.592 185.091 163.487 1.00 165.70 ? 117 TYR M CD1   1 
ATOM   909  C CD2   . TYR A 1 112 ? 116.035 183.433 162.780 1.00 165.70 ? 117 TYR M CD2   1 
ATOM   910  C CE1   . TYR A 1 112 ? 116.929 185.195 164.702 1.00 165.70 ? 117 TYR M CE1   1 
ATOM   911  C CE2   . TYR A 1 112 ? 115.367 183.531 163.984 1.00 165.70 ? 117 TYR M CE2   1 
ATOM   912  C CZ    . TYR A 1 112 ? 115.816 184.408 164.942 1.00 165.70 ? 117 TYR M CZ    1 
ATOM   913  O OH    . TYR A 1 112 ? 115.142 184.496 166.137 1.00 165.70 ? 117 TYR M OH    1 
ATOM   914  N N     . SER A 1 113 ? 120.949 184.740 160.268 1.00 162.05 ? 118 SER M N     1 
ATOM   915  C CA    . SER A 1 113 ? 122.087 184.341 159.448 1.00 162.05 ? 118 SER M CA    1 
ATOM   916  C C     . SER A 1 113 ? 122.929 183.316 160.197 1.00 162.05 ? 118 SER M C     1 
ATOM   917  O O     . SER A 1 113 ? 124.153 183.418 160.285 1.00 162.05 ? 118 SER M O     1 
ATOM   918  C CB    . SER A 1 113 ? 122.904 185.562 159.033 1.00 162.05 ? 118 SER M CB    1 
ATOM   919  O OG    . SER A 1 113 ? 123.399 186.251 160.164 1.00 162.05 ? 118 SER M OG    1 
ATOM   920  N N     . GLY A 1 114 ? 122.270 182.315 160.747 1.00 159.29 ? 119 GLY M N     1 
ATOM   921  C CA    . GLY A 1 114 ? 122.950 181.267 161.510 1.00 159.29 ? 119 GLY M CA    1 
ATOM   922  C C     . GLY A 1 114 ? 122.996 181.598 163.003 1.00 159.29 ? 119 GLY M C     1 
ATOM   923  O O     . GLY A 1 114 ? 121.967 181.587 163.668 1.00 159.29 ? 119 GLY M O     1 
ATOM   924  N N     . LEU A 1 115 ? 124.196 181.877 163.509 1.00 152.97 ? 120 LEU M N     1 
ATOM   925  C CA    . LEU A 1 115 ? 124.359 182.271 164.900 1.00 152.97 ? 120 LEU M CA    1 
ATOM   926  C C     . LEU A 1 115 ? 124.329 183.779 165.092 1.00 152.97 ? 120 LEU M C     1 
ATOM   927  O O     . LEU A 1 115 ? 124.480 184.246 166.225 1.00 152.97 ? 120 LEU M O     1 
ATOM   928  C CB    . LEU A 1 115 ? 125.665 181.707 165.466 1.00 152.97 ? 120 LEU M CB    1 
ATOM   929  C CG    . LEU A 1 115 ? 125.649 180.272 166.000 1.00 152.97 ? 120 LEU M CG    1 
ATOM   930  C CD1   . LEU A 1 115 ? 124.684 180.150 167.163 1.00 152.97 ? 120 LEU M CD1   1 
ATOM   931  C CD2   . LEU A 1 115 ? 125.321 179.255 164.916 1.00 152.97 ? 120 LEU M CD2   1 
ATOM   932  N N     . PHE A 1 116 ? 124.144 184.542 164.020 1.00 152.39 ? 121 PHE M N     1 
ATOM   933  C CA    . PHE A 1 116 ? 124.055 185.990 164.080 1.00 152.39 ? 121 PHE M CA    1 
ATOM   934  C C     . PHE A 1 116 ? 122.605 186.451 164.140 1.00 152.39 ? 121 PHE M C     1 
ATOM   935  O O     . PHE A 1 116 ? 121.662 185.661 164.068 1.00 152.39 ? 121 PHE M O     1 
ATOM   936  C CB    . PHE A 1 116 ? 124.725 186.628 162.867 1.00 152.39 ? 121 PHE M CB    1 
ATOM   937  C CG    . PHE A 1 116 ? 126.217 186.661 162.936 1.00 152.39 ? 121 PHE M CG    1 
ATOM   938  C CD1   . PHE A 1 116 ? 126.871 186.567 164.146 1.00 152.39 ? 121 PHE M CD1   1 
ATOM   939  C CD2   . PHE A 1 116 ? 126.967 186.777 161.780 1.00 152.39 ? 121 PHE M CD2   1 
ATOM   940  C CE1   . PHE A 1 116 ? 128.239 186.599 164.203 1.00 152.39 ? 121 PHE M CE1   1 
ATOM   941  C CE2   . PHE A 1 116 ? 128.338 186.808 161.836 1.00 152.39 ? 121 PHE M CE2   1 
ATOM   942  C CZ    . PHE A 1 116 ? 128.972 186.722 163.049 1.00 152.39 ? 121 PHE M CZ    1 
ATOM   943  N N     . CYS A 1 117 ? 122.442 187.764 164.284 1.00 155.31 ? 122 CYS M N     1 
ATOM   944  C CA    . CYS A 1 117 ? 121.168 188.449 164.097 1.00 155.31 ? 122 CYS M CA    1 
ATOM   945  C C     . CYS A 1 117 ? 121.463 189.775 163.415 1.00 155.31 ? 122 CYS M C     1 
ATOM   946  O O     . CYS A 1 117 ? 122.009 190.689 164.040 1.00 155.31 ? 122 CYS M O     1 
ATOM   947  C CB    . CYS A 1 117 ? 120.450 188.671 165.423 1.00 155.31 ? 122 CYS M CB    1 
ATOM   948  S SG    . CYS A 1 117 ? 119.179 189.938 165.340 1.00 155.31 ? 122 CYS M SG    1 
ATOM   949  N N     . VAL A 1 118 ? 121.107 189.885 162.144 1.00 158.22 ? 123 VAL M N     1 
ATOM   950  C CA    . VAL A 1 118 ? 121.450 191.043 161.332 1.00 158.22 ? 123 VAL M CA    1 
ATOM   951  C C     . VAL A 1 118 ? 120.264 191.993 161.320 1.00 158.22 ? 123 VAL M C     1 
ATOM   952  O O     . VAL A 1 118 ? 119.111 191.555 161.239 1.00 158.22 ? 123 VAL M O     1 
ATOM   953  C CB    . VAL A 1 118 ? 121.839 190.626 159.907 1.00 158.22 ? 123 VAL M CB    1 
ATOM   954  C CG1   . VAL A 1 118 ? 122.561 191.747 159.221 1.00 158.22 ? 123 VAL M CG1   1 
ATOM   955  C CG2   . VAL A 1 118 ? 122.693 189.377 159.942 1.00 158.22 ? 123 VAL M CG2   1 
ATOM   956  N N     . THR A 1 119 ? 120.541 193.290 161.405 1.00 159.28 ? 124 THR M N     1 
ATOM   957  C CA    . THR A 1 119 ? 119.493 194.300 161.510 1.00 159.28 ? 124 THR M CA    1 
ATOM   958  C C     . THR A 1 119 ? 119.908 195.538 160.730 1.00 159.28 ? 124 THR M C     1 
ATOM   959  O O     . THR A 1 119 ? 120.811 196.267 161.151 1.00 159.28 ? 124 THR M O     1 
ATOM   960  C CB    . THR A 1 119 ? 119.221 194.655 162.971 1.00 159.28 ? 124 THR M CB    1 
ATOM   961  O OG1   . THR A 1 119 ? 118.663 193.520 163.644 1.00 159.28 ? 124 THR M OG1   1 
ATOM   962  C CG2   . THR A 1 119 ? 118.264 195.836 163.071 1.00 159.28 ? 124 THR M CG2   1 
ATOM   963  N N     . VAL A 1 120 ? 119.252 195.781 159.607 1.00 162.51 ? 125 VAL M N     1 
ATOM   964  C CA    . VAL A 1 120 ? 119.388 197.045 158.897 1.00 162.51 ? 125 VAL M CA    1 
ATOM   965  C C     . VAL A 1 120 ? 118.364 198.014 159.466 1.00 162.51 ? 125 VAL M C     1 
ATOM   966  O O     . VAL A 1 120 ? 117.186 197.673 159.611 1.00 162.51 ? 125 VAL M O     1 
ATOM   967  C CB    . VAL A 1 120 ? 119.208 196.852 157.382 1.00 162.51 ? 125 VAL M CB    1 
ATOM   968  C CG1   . VAL A 1 120 ? 117.868 196.211 157.067 1.00 162.51 ? 125 VAL M CG1   1 
ATOM   969  C CG2   . VAL A 1 120 ? 119.347 198.181 156.665 1.00 162.51 ? 125 VAL M CG2   1 
ATOM   970  N N     . ASN A 1 121 ? 118.810 199.208 159.822 1.00 164.04 ? 126 ASN M N     1 
ATOM   971  C CA    . ASN A 1 121 ? 117.924 200.142 160.504 1.00 164.04 ? 126 ASN M CA    1 
ATOM   972  C C     . ASN A 1 121 ? 116.887 200.693 159.533 1.00 164.04 ? 126 ASN M C     1 
ATOM   973  O O     . ASN A 1 121 ? 117.246 201.162 158.447 1.00 164.04 ? 126 ASN M O     1 
ATOM   974  C CB    . ASN A 1 121 ? 118.719 201.285 161.124 1.00 164.04 ? 126 ASN M CB    1 
ATOM   975  C CG    . ASN A 1 121 ? 119.522 202.051 160.102 1.00 164.04 ? 126 ASN M CG    1 
ATOM   976  O OD1   . ASN A 1 121 ? 120.152 201.459 159.231 1.00 164.04 ? 126 ASN M OD1   1 
ATOM   977  N ND2   . ASN A 1 121 ? 119.495 203.374 160.194 1.00 164.04 ? 126 ASN M ND2   1 
ATOM   978  N N     . PRO A 1 122 ? 115.603 200.631 159.865 1.00 166.72 ? 127 PRO M N     1 
ATOM   979  C CA    . PRO A 1 122 ? 114.612 201.400 159.112 1.00 166.72 ? 127 PRO M CA    1 
ATOM   980  C C     . PRO A 1 122 ? 114.640 202.859 159.529 1.00 166.72 ? 127 PRO M C     1 
ATOM   981  O O     . PRO A 1 122 ? 114.847 203.195 160.697 1.00 166.72 ? 127 PRO M O     1 
ATOM   982  C CB    . PRO A 1 122 ? 113.285 200.737 159.498 1.00 166.72 ? 127 PRO M CB    1 
ATOM   983  C CG    . PRO A 1 122 ? 113.533 200.198 160.856 1.00 166.72 ? 127 PRO M CG    1 
ATOM   984  C CD    . PRO A 1 122 ? 114.979 199.777 160.889 1.00 166.72 ? 127 PRO M CD    1 
ATOM   985  N N     . TYR A 1 123 ? 114.425 203.733 158.553 1.00 167.83 ? 128 TYR M N     1 
ATOM   986  C CA    . TYR A 1 123 ? 114.515 205.165 158.789 1.00 167.83 ? 128 TYR M CA    1 
ATOM   987  C C     . TYR A 1 123 ? 113.193 205.798 159.196 1.00 167.83 ? 128 TYR M C     1 
ATOM   988  O O     . TYR A 1 123 ? 113.177 206.981 159.547 1.00 167.83 ? 128 TYR M O     1 
ATOM   989  C CB    . TYR A 1 123 ? 115.050 205.872 157.547 1.00 167.83 ? 128 TYR M CB    1 
ATOM   990  C CG    . TYR A 1 123 ? 116.489 205.563 157.222 1.00 167.83 ? 128 TYR M CG    1 
ATOM   991  C CD1   . TYR A 1 123 ? 117.498 205.799 158.144 1.00 167.83 ? 128 TYR M CD1   1 
ATOM   992  C CD2   . TYR A 1 123 ? 116.841 205.061 155.980 1.00 167.83 ? 128 TYR M CD2   1 
ATOM   993  C CE1   . TYR A 1 123 ? 118.812 205.527 157.840 1.00 167.83 ? 128 TYR M CE1   1 
ATOM   994  C CE2   . TYR A 1 123 ? 118.152 204.790 155.667 1.00 167.83 ? 128 TYR M CE2   1 
ATOM   995  C CZ    . TYR A 1 123 ? 119.133 205.022 156.598 1.00 167.83 ? 128 TYR M CZ    1 
ATOM   996  O OH    . TYR A 1 123 ? 120.438 204.748 156.275 1.00 167.83 ? 128 TYR M OH    1 
ATOM   997  N N     . LYS A 1 124 ? 112.091 205.050 159.171 1.00 168.43 ? 129 LYS M N     1 
ATOM   998  C CA    . LYS A 1 124 ? 110.795 205.568 159.581 1.00 168.43 ? 129 LYS M CA    1 
ATOM   999  C C     . LYS A 1 124 ? 110.195 204.650 160.637 1.00 168.43 ? 129 LYS M C     1 
ATOM   1000 O O     . LYS A 1 124 ? 110.606 203.499 160.796 1.00 168.43 ? 129 LYS M O     1 
ATOM   1001 C CB    . LYS A 1 124 ? 109.832 205.725 158.388 1.00 168.43 ? 129 LYS M CB    1 
ATOM   1002 C CG    . LYS A 1 124 ? 109.521 204.442 157.628 1.00 168.43 ? 129 LYS M CG    1 
ATOM   1003 C CD    . LYS A 1 124 ? 108.770 204.741 156.333 1.00 168.43 ? 129 LYS M CD    1 
ATOM   1004 C CE    . LYS A 1 124 ? 108.255 203.477 155.662 1.00 168.43 ? 129 LYS M CE    1 
ATOM   1005 N NZ    . LYS A 1 124 ? 109.331 202.472 155.476 1.00 168.43 ? 129 LYS M NZ    1 
ATOM   1006 N N     . TRP A 1 125 ? 109.232 205.189 161.378 1.00 169.19 ? 130 TRP M N     1 
ATOM   1007 C CA    . TRP A 1 125 ? 108.619 204.450 162.472 1.00 169.19 ? 130 TRP M CA    1 
ATOM   1008 C C     . TRP A 1 125 ? 107.852 203.244 161.945 1.00 169.19 ? 130 TRP M C     1 
ATOM   1009 O O     . TRP A 1 125 ? 107.216 203.303 160.890 1.00 169.19 ? 130 TRP M O     1 
ATOM   1010 C CB    . TRP A 1 125 ? 107.684 205.369 163.255 1.00 169.19 ? 130 TRP M CB    1 
ATOM   1011 C CG    . TRP A 1 125 ? 107.127 204.780 164.517 1.00 169.19 ? 130 TRP M CG    1 
ATOM   1012 C CD1   . TRP A 1 125 ? 106.197 203.787 164.622 1.00 169.19 ? 130 TRP M CD1   1 
ATOM   1013 C CD2   . TRP A 1 125 ? 107.439 205.179 165.858 1.00 169.19 ? 130 TRP M CD2   1 
ATOM   1014 N NE1   . TRP A 1 125 ? 105.924 203.530 165.943 1.00 169.19 ? 130 TRP M NE1   1 
ATOM   1015 C CE2   . TRP A 1 125 ? 106.670 204.374 166.723 1.00 169.19 ? 130 TRP M CE2   1 
ATOM   1016 C CE3   . TRP A 1 125 ? 108.300 206.134 166.412 1.00 169.19 ? 130 TRP M CE3   1 
ATOM   1017 C CZ2   . TRP A 1 125 ? 106.737 204.493 168.110 1.00 169.19 ? 130 TRP M CZ2   1 
ATOM   1018 C CZ3   . TRP A 1 125 ? 108.364 206.250 167.788 1.00 169.19 ? 130 TRP M CZ3   1 
ATOM   1019 C CH2   . TRP A 1 125 ? 107.588 205.434 168.622 1.00 169.19 ? 130 TRP M CH2   1 
ATOM   1020 N N     . LEU A 1 126 ? 107.924 202.141 162.684 1.00 169.15 ? 131 LEU M N     1 
ATOM   1021 C CA    . LEU A 1 126 ? 107.152 200.945 162.392 1.00 169.15 ? 131 LEU M CA    1 
ATOM   1022 C C     . LEU A 1 126 ? 106.405 200.484 163.631 1.00 169.15 ? 131 LEU M C     1 
ATOM   1023 O O     . LEU A 1 126 ? 106.835 200.747 164.760 1.00 169.15 ? 131 LEU M O     1 
ATOM   1024 C CB    . LEU A 1 126 ? 108.034 199.794 161.892 1.00 169.15 ? 131 LEU M CB    1 
ATOM   1025 C CG    . LEU A 1 126 ? 108.416 199.711 160.416 1.00 169.15 ? 131 LEU M CG    1 
ATOM   1026 C CD1   . LEU A 1 126 ? 109.461 200.744 160.060 1.00 169.15 ? 131 LEU M CD1   1 
ATOM   1027 C CD2   . LEU A 1 126 ? 108.908 198.309 160.091 1.00 169.15 ? 131 LEU M CD2   1 
ATOM   1028 N N     . PRO A 1 127 ? 105.278 199.787 163.447 1.00 169.94 ? 132 PRO M N     1 
ATOM   1029 C CA    . PRO A 1 127 ? 104.591 199.159 164.586 1.00 169.94 ? 132 PRO M CA    1 
ATOM   1030 C C     . PRO A 1 127 ? 105.325 197.962 165.166 1.00 169.94 ? 132 PRO M C     1 
ATOM   1031 O O     . PRO A 1 127 ? 104.804 197.330 166.091 1.00 169.94 ? 132 PRO M O     1 
ATOM   1032 C CB    . PRO A 1 127 ? 103.246 198.733 163.984 1.00 169.94 ? 132 PRO M CB    1 
ATOM   1033 C CG    . PRO A 1 127 ? 103.529 198.551 162.533 1.00 169.94 ? 132 PRO M CG    1 
ATOM   1034 C CD    . PRO A 1 127 ? 104.536 199.606 162.186 1.00 169.94 ? 132 PRO M CD    1 
ATOM   1035 N N     . VAL A 1 128 ? 106.513 197.630 164.654 1.00 168.64 ? 133 VAL M N     1 
ATOM   1036 C CA    . VAL A 1 128 ? 107.255 196.479 165.150 1.00 168.64 ? 133 VAL M CA    1 
ATOM   1037 C C     . VAL A 1 128 ? 107.817 196.718 166.544 1.00 168.64 ? 133 VAL M C     1 
ATOM   1038 O O     . VAL A 1 128 ? 108.232 195.765 167.213 1.00 168.64 ? 133 VAL M O     1 
ATOM   1039 C CB    . VAL A 1 128 ? 108.383 196.116 164.169 1.00 168.64 ? 133 VAL M CB    1 
ATOM   1040 C CG1   . VAL A 1 128 ? 107.804 195.738 162.819 1.00 168.64 ? 133 VAL M CG1   1 
ATOM   1041 C CG2   . VAL A 1 128 ? 109.360 197.269 164.033 1.00 168.64 ? 133 VAL M CG2   1 
ATOM   1042 N N     . TYR A 1 129 ? 107.851 197.969 166.998 1.00 167.09 ? 134 TYR M N     1 
ATOM   1043 C CA    . TYR A 1 129 ? 108.349 198.314 168.322 1.00 167.09 ? 134 TYR M CA    1 
ATOM   1044 C C     . TYR A 1 129 ? 107.226 198.632 169.298 1.00 167.09 ? 134 TYR M C     1 
ATOM   1045 O O     . TYR A 1 129 ? 107.483 199.193 170.368 1.00 167.09 ? 134 TYR M O     1 
ATOM   1046 C CB    . TYR A 1 129 ? 109.322 199.488 168.221 1.00 167.09 ? 134 TYR M CB    1 
ATOM   1047 C CG    . TYR A 1 129 ? 110.505 199.196 167.322 1.00 167.09 ? 134 TYR M CG    1 
ATOM   1048 C CD1   . TYR A 1 129 ? 111.036 197.915 167.238 1.00 167.09 ? 134 TYR M CD1   1 
ATOM   1049 C CD2   . TYR A 1 129 ? 111.081 200.195 166.550 1.00 167.09 ? 134 TYR M CD2   1 
ATOM   1050 C CE1   . TYR A 1 129 ? 112.113 197.641 166.417 1.00 167.09 ? 134 TYR M CE1   1 
ATOM   1051 C CE2   . TYR A 1 129 ? 112.159 199.928 165.726 1.00 167.09 ? 134 TYR M CE2   1 
ATOM   1052 C CZ    . TYR A 1 129 ? 112.669 198.650 165.663 1.00 167.09 ? 134 TYR M CZ    1 
ATOM   1053 O OH    . TYR A 1 129 ? 113.739 198.378 164.843 1.00 167.09 ? 134 TYR M OH    1 
ATOM   1054 N N     . THR A 1 130 ? 105.991 198.296 168.949 1.00 167.71 ? 135 THR M N     1 
ATOM   1055 C CA    . THR A 1 130 ? 104.876 198.486 169.861 1.00 167.71 ? 135 THR M CA    1 
ATOM   1056 C C     . THR A 1 130 ? 104.907 197.416 170.949 1.00 167.71 ? 135 THR M C     1 
ATOM   1057 O O     . THR A 1 130 ? 105.317 196.280 170.692 1.00 167.71 ? 135 THR M O     1 
ATOM   1058 C CB    . THR A 1 130 ? 103.557 198.422 169.098 1.00 167.71 ? 135 THR M CB    1 
ATOM   1059 O OG1   . THR A 1 130 ? 103.607 197.345 168.153 1.00 167.71 ? 135 THR M OG1   1 
ATOM   1060 C CG2   . THR A 1 130 ? 103.317 199.726 168.357 1.00 167.71 ? 135 THR M CG2   1 
ATOM   1061 N N     . PRO A 1 131 ? 104.474 197.741 172.171 1.00 166.63 ? 136 PRO M N     1 
ATOM   1062 C CA    . PRO A 1 131 ? 104.583 196.772 173.276 1.00 166.63 ? 136 PRO M CA    1 
ATOM   1063 C C     . PRO A 1 131 ? 103.756 195.514 173.077 1.00 166.63 ? 136 PRO M C     1 
ATOM   1064 O O     . PRO A 1 131 ? 103.947 194.537 173.819 1.00 166.63 ? 136 PRO M O     1 
ATOM   1065 C CB    . PRO A 1 131 ? 104.089 197.571 174.489 1.00 166.63 ? 136 PRO M CB    1 
ATOM   1066 C CG    . PRO A 1 131 ? 103.184 198.607 173.902 1.00 166.63 ? 136 PRO M CG    1 
ATOM   1067 C CD    . PRO A 1 131 ? 103.800 198.982 172.587 1.00 166.63 ? 136 PRO M CD    1 
ATOM   1068 N N     . GLU A 1 132 ? 102.852 195.501 172.099 1.00 167.90 ? 137 GLU M N     1 
ATOM   1069 C CA    . GLU A 1 132 ? 102.005 194.333 171.913 1.00 167.90 ? 137 GLU M CA    1 
ATOM   1070 C C     . GLU A 1 132 ? 102.815 193.133 171.443 1.00 167.90 ? 137 GLU M C     1 
ATOM   1071 O O     . GLU A 1 132 ? 102.650 192.030 171.970 1.00 167.90 ? 137 GLU M O     1 
ATOM   1072 C CB    . GLU A 1 132 ? 100.865 194.660 170.946 1.00 167.90 ? 137 GLU M CB    1 
ATOM   1073 C CG    . GLU A 1 132 ? 101.285 195.127 169.565 1.00 167.90 ? 137 GLU M CG    1 
ATOM   1074 C CD    . GLU A 1 132 ? 101.483 193.977 168.606 1.00 167.90 ? 137 GLU M CD    1 
ATOM   1075 O OE1   . GLU A 1 132 ? 102.290 194.118 167.665 1.00 167.90 ? 137 GLU M OE1   1 
ATOM   1076 O OE2   . GLU A 1 132 ? 100.842 192.926 168.811 1.00 167.90 ? 137 GLU M OE2   1 
ATOM   1077 N N     . VAL A 1 133 ? 103.709 193.325 170.471 1.00 165.96 ? 138 VAL M N     1 
ATOM   1078 C CA    . VAL A 1 133 ? 104.538 192.213 170.019 1.00 165.96 ? 138 VAL M CA    1 
ATOM   1079 C C     . VAL A 1 133 ? 105.497 191.795 171.121 1.00 165.96 ? 138 VAL M C     1 
ATOM   1080 O O     . VAL A 1 133 ? 105.805 190.609 171.279 1.00 165.96 ? 138 VAL M O     1 
ATOM   1081 C CB    . VAL A 1 133 ? 105.277 192.578 168.719 1.00 165.96 ? 138 VAL M CB    1 
ATOM   1082 C CG1   . VAL A 1 133 ? 106.284 193.696 168.952 1.00 165.96 ? 138 VAL M CG1   1 
ATOM   1083 C CG2   . VAL A 1 133 ? 105.959 191.349 168.141 1.00 165.96 ? 138 VAL M CG2   1 
ATOM   1084 N N     . VAL A 1 134 ? 105.954 192.759 171.920 1.00 165.20 ? 139 VAL M N     1 
ATOM   1085 C CA    . VAL A 1 134 ? 106.817 192.458 173.058 1.00 165.20 ? 139 VAL M CA    1 
ATOM   1086 C C     . VAL A 1 134 ? 106.129 191.480 174.000 1.00 165.20 ? 139 VAL M C     1 
ATOM   1087 O O     . VAL A 1 134 ? 106.663 190.412 174.319 1.00 165.20 ? 139 VAL M O     1 
ATOM   1088 C CB    . VAL A 1 134 ? 107.200 193.760 173.780 1.00 165.20 ? 139 VAL M CB    1 
ATOM   1089 C CG1   . VAL A 1 134 ? 108.327 193.516 174.749 1.00 165.20 ? 139 VAL M CG1   1 
ATOM   1090 C CG2   . VAL A 1 134 ? 107.586 194.818 172.771 1.00 165.20 ? 139 VAL M CG2   1 
ATOM   1091 N N     . ALA A 1 135 ? 104.923 191.828 174.448 1.00 166.53 ? 140 ALA M N     1 
ATOM   1092 C CA    . ALA A 1 135 ? 104.208 190.972 175.390 1.00 166.53 ? 140 ALA M CA    1 
ATOM   1093 C C     . ALA A 1 135 ? 103.768 189.667 174.736 1.00 166.53 ? 140 ALA M C     1 
ATOM   1094 O O     . ALA A 1 135 ? 103.755 188.615 175.386 1.00 166.53 ? 140 ALA M O     1 
ATOM   1095 C CB    . ALA A 1 135 ? 103.006 191.715 175.971 1.00 166.53 ? 140 ALA M CB    1 
ATOM   1096 N N     . ALA A 1 136 ? 103.412 189.710 173.453 1.00 167.36 ? 141 ALA M N     1 
ATOM   1097 C CA    . ALA A 1 136 ? 102.871 188.543 172.773 1.00 167.36 ? 141 ALA M CA    1 
ATOM   1098 C C     . ALA A 1 136 ? 103.942 187.573 172.304 1.00 167.36 ? 141 ALA M C     1 
ATOM   1099 O O     . ALA A 1 136 ? 103.607 186.438 171.951 1.00 167.36 ? 141 ALA M O     1 
ATOM   1100 C CB    . ALA A 1 136 ? 102.020 188.981 171.578 1.00 167.36 ? 141 ALA M CB    1 
ATOM   1101 N N     . TYR A 1 137 ? 105.212 187.976 172.284 1.00 165.73 ? 142 TYR M N     1 
ATOM   1102 C CA    . TYR A 1 137 ? 106.242 187.008 171.941 1.00 165.73 ? 142 TYR M CA    1 
ATOM   1103 C C     . TYR A 1 137 ? 106.440 185.990 173.050 1.00 165.73 ? 142 TYR M C     1 
ATOM   1104 O O     . TYR A 1 137 ? 106.861 184.860 172.778 1.00 165.73 ? 142 TYR M O     1 
ATOM   1105 C CB    . TYR A 1 137 ? 107.571 187.695 171.633 1.00 165.73 ? 142 TYR M CB    1 
ATOM   1106 C CG    . TYR A 1 137 ? 108.639 186.698 171.236 1.00 165.73 ? 142 TYR M CG    1 
ATOM   1107 C CD1   . TYR A 1 137 ? 108.784 186.302 169.914 1.00 165.73 ? 142 TYR M CD1   1 
ATOM   1108 C CD2   . TYR A 1 137 ? 109.481 186.136 172.183 1.00 165.73 ? 142 TYR M CD2   1 
ATOM   1109 C CE1   . TYR A 1 137 ? 109.739 185.387 169.549 1.00 165.73 ? 142 TYR M CE1   1 
ATOM   1110 C CE2   . TYR A 1 137 ? 110.435 185.214 171.826 1.00 165.73 ? 142 TYR M CE2   1 
ATOM   1111 C CZ    . TYR A 1 137 ? 110.563 184.845 170.510 1.00 165.73 ? 142 TYR M CZ    1 
ATOM   1112 O OH    . TYR A 1 137 ? 111.526 183.928 170.159 1.00 165.73 ? 142 TYR M OH    1 
ATOM   1113 N N     . ARG A 1 138 ? 106.138 186.363 174.290 1.00 164.47 ? 143 ARG M N     1 
ATOM   1114 C CA    . ARG A 1 138 ? 106.375 185.476 175.418 1.00 164.47 ? 143 ARG M CA    1 
ATOM   1115 C C     . ARG A 1 138 ? 105.615 184.170 175.235 1.00 164.47 ? 143 ARG M C     1 
ATOM   1116 O O     . ARG A 1 138 ? 104.382 184.143 175.292 1.00 164.47 ? 143 ARG M O     1 
ATOM   1117 C CB    . ARG A 1 138 ? 105.964 186.158 176.721 1.00 164.47 ? 143 ARG M CB    1 
ATOM   1118 C CG    . ARG A 1 138 ? 106.941 187.222 177.192 1.00 164.47 ? 143 ARG M CG    1 
ATOM   1119 C CD    . ARG A 1 138 ? 108.359 186.690 177.245 1.00 164.47 ? 143 ARG M CD    1 
ATOM   1120 N NE    . ARG A 1 138 ? 108.469 185.450 178.008 1.00 164.47 ? 143 ARG M NE    1 
ATOM   1121 C CZ    . ARG A 1 138 ? 108.875 184.293 177.495 1.00 164.47 ? 143 ARG M CZ    1 
ATOM   1122 N NH1   . ARG A 1 138 ? 109.211 184.215 176.214 1.00 164.47 ? 143 ARG M NH1   1 
ATOM   1123 N NH2   . ARG A 1 138 ? 108.950 183.217 178.262 1.00 164.47 ? 143 ARG M NH2   1 
ATOM   1124 N N     . GLY A 1 139 ? 106.359 183.087 175.017 1.00 165.96 ? 144 GLY M N     1 
ATOM   1125 C CA    . GLY A 1 139 ? 105.785 181.779 174.770 1.00 165.96 ? 144 GLY M CA    1 
ATOM   1126 C C     . GLY A 1 139 ? 106.070 181.201 173.400 1.00 165.96 ? 144 GLY M C     1 
ATOM   1127 O O     . GLY A 1 139 ? 105.632 180.078 173.121 1.00 165.96 ? 144 GLY M O     1 
ATOM   1128 N N     . LYS A 1 140 ? 106.793 181.915 172.540 1.00 166.98 ? 145 LYS M N     1 
ATOM   1129 C CA    . LYS A 1 140 ? 107.159 181.421 171.223 1.00 166.98 ? 145 LYS M CA    1 
ATOM   1130 C C     . LYS A 1 140 ? 108.659 181.165 171.164 1.00 166.98 ? 145 LYS M C     1 
ATOM   1131 O O     . LYS A 1 140 ? 109.444 181.801 171.873 1.00 166.98 ? 145 LYS M O     1 
ATOM   1132 C CB    . LYS A 1 140 ? 106.752 182.407 170.126 1.00 166.98 ? 145 LYS M CB    1 
ATOM   1133 C CG    . LYS A 1 140 ? 105.475 183.172 170.421 1.00 166.98 ? 145 LYS M CG    1 
ATOM   1134 C CD    . LYS A 1 140 ? 104.925 183.840 169.169 1.00 166.98 ? 145 LYS M CD    1 
ATOM   1135 C CE    . LYS A 1 140 ? 105.370 185.282 169.077 1.00 166.98 ? 145 LYS M CE    1 
ATOM   1136 N NZ    . LYS A 1 140 ? 104.428 186.125 168.301 1.00 166.98 ? 145 LYS M NZ    1 
ATOM   1137 N N     . LYS A 1 141 ? 109.049 180.234 170.300 1.00 165.44 ? 146 LYS M N     1 
ATOM   1138 C CA    . LYS A 1 141 ? 110.405 179.710 170.264 1.00 165.44 ? 146 LYS M CA    1 
ATOM   1139 C C     . LYS A 1 141 ? 111.257 180.438 169.225 1.00 165.44 ? 146 LYS M C     1 
ATOM   1140 O O     . LYS A 1 141 ? 110.750 181.119 168.331 1.00 165.44 ? 146 LYS M O     1 
ATOM   1141 C CB    . LYS A 1 141 ? 110.379 178.205 169.973 1.00 165.44 ? 146 LYS M CB    1 
ATOM   1142 C CG    . LYS A 1 141 ? 111.592 177.448 170.476 1.00 165.44 ? 146 LYS M CG    1 
ATOM   1143 C CD    . LYS A 1 141 ? 112.009 177.932 171.852 1.00 165.44 ? 146 LYS M CD    1 
ATOM   1144 C CE    . LYS A 1 141 ? 113.313 177.293 172.283 1.00 165.44 ? 146 LYS M CE    1 
ATOM   1145 N NZ    . LYS A 1 141 ? 113.828 177.905 173.534 1.00 165.44 ? 146 LYS M NZ    1 
ATOM   1146 N N     . ARG A 1 142 ? 112.578 180.277 169.365 1.00 165.04 ? 147 ARG M N     1 
ATOM   1147 C CA    . ARG A 1 142 ? 113.527 180.896 168.442 1.00 165.04 ? 147 ARG M CA    1 
ATOM   1148 C C     . ARG A 1 142 ? 113.513 180.221 167.079 1.00 165.04 ? 147 ARG M C     1 
ATOM   1149 O O     . ARG A 1 142 ? 113.579 180.895 166.045 1.00 165.04 ? 147 ARG M O     1 
ATOM   1150 C CB    . ARG A 1 142 ? 114.931 180.854 169.045 1.00 165.04 ? 147 ARG M CB    1 
ATOM   1151 C CG    . ARG A 1 142 ? 116.032 181.439 168.173 1.00 165.04 ? 147 ARG M CG    1 
ATOM   1152 C CD    . ARG A 1 142 ? 116.890 180.345 167.546 1.00 165.04 ? 147 ARG M CD    1 
ATOM   1153 N NE    . ARG A 1 142 ? 117.992 180.893 166.760 1.00 165.04 ? 147 ARG M NE    1 
ATOM   1154 C CZ    . ARG A 1 142 ? 117.930 181.137 165.453 1.00 165.04 ? 147 ARG M CZ    1 
ATOM   1155 N NH1   . ARG A 1 142 ? 116.825 180.854 164.770 1.00 165.04 ? 147 ARG M NH1   1 
ATOM   1156 N NH2   . ARG A 1 142 ? 118.977 181.642 164.818 1.00 165.04 ? 147 ARG M NH2   1 
ATOM   1157 N N     . SER A 1 143 ? 113.426 178.893 167.059 1.00 165.60 ? 148 SER M N     1 
ATOM   1158 C CA    . SER A 1 143 ? 113.568 178.153 165.811 1.00 165.60 ? 148 SER M CA    1 
ATOM   1159 C C     . SER A 1 143 ? 112.454 178.488 164.826 1.00 165.60 ? 148 SER M C     1 
ATOM   1160 O O     . SER A 1 143 ? 112.653 178.413 163.608 1.00 165.60 ? 148 SER M O     1 
ATOM   1161 C CB    . SER A 1 143 ? 113.593 176.656 166.109 1.00 165.60 ? 148 SER M CB    1 
ATOM   1162 O OG    . SER A 1 143 ? 114.387 176.382 167.251 1.00 165.60 ? 148 SER M OG    1 
ATOM   1163 N N     . GLU A 1 144 ? 111.272 178.847 165.329 1.00 166.71 ? 149 GLU M N     1 
ATOM   1164 C CA    . GLU A 1 144 ? 110.104 179.087 164.484 1.00 166.71 ? 149 GLU M CA    1 
ATOM   1165 C C     . GLU A 1 144 ? 109.783 180.563 164.287 1.00 166.71 ? 149 GLU M C     1 
ATOM   1166 O O     . GLU A 1 144 ? 109.440 180.970 163.172 1.00 166.71 ? 149 GLU M O     1 
ATOM   1167 C CB    . GLU A 1 144 ? 108.876 178.378 165.065 1.00 166.71 ? 149 GLU M CB    1 
ATOM   1168 C CG    . GLU A 1 144 ? 108.981 176.857 165.145 1.00 166.71 ? 149 GLU M CG    1 
ATOM   1169 C CD    . GLU A 1 144 ? 110.033 176.372 166.133 1.00 166.71 ? 149 GLU M CD    1 
ATOM   1170 O OE1   . GLU A 1 144 ? 110.449 177.169 167.001 1.00 166.71 ? 149 GLU M OE1   1 
ATOM   1171 O OE2   . GLU A 1 144 ? 110.444 175.197 166.040 1.00 166.71 ? 149 GLU M OE2   1 
ATOM   1172 N N     . ALA A 1 145 ? 109.887 181.375 165.334 1.00 167.09 ? 150 ALA M N     1 
ATOM   1173 C CA    . ALA A 1 145 ? 109.506 182.774 165.222 1.00 167.09 ? 150 ALA M CA    1 
ATOM   1174 C C     . ALA A 1 145 ? 110.422 183.492 164.237 1.00 167.09 ? 150 ALA M C     1 
ATOM   1175 O O     . ALA A 1 145 ? 111.611 183.171 164.146 1.00 167.09 ? 150 ALA M O     1 
ATOM   1176 C CB    . ALA A 1 145 ? 109.567 183.463 166.582 1.00 167.09 ? 150 ALA M CB    1 
ATOM   1177 N N     . PRO A 1 146 ? 109.900 184.452 163.479 1.00 168.27 ? 151 PRO M N     1 
ATOM   1178 C CA    . PRO A 1 146 ? 110.727 185.164 162.502 1.00 168.27 ? 151 PRO M CA    1 
ATOM   1179 C C     . PRO A 1 146 ? 111.774 186.009 163.202 1.00 168.27 ? 151 PRO M C     1 
ATOM   1180 O O     . PRO A 1 146 ? 111.621 186.341 164.387 1.00 168.27 ? 151 PRO M O     1 
ATOM   1181 C CB    . PRO A 1 146 ? 109.712 186.034 161.745 1.00 168.27 ? 151 PRO M CB    1 
ATOM   1182 C CG    . PRO A 1 146 ? 108.376 185.436 162.049 1.00 168.27 ? 151 PRO M CG    1 
ATOM   1183 C CD    . PRO A 1 146 ? 108.494 184.882 163.428 1.00 168.27 ? 151 PRO M CD    1 
ATOM   1184 N N     . PRO A 1 147 ? 112.850 186.377 162.504 1.00 165.82 ? 152 PRO M N     1 
ATOM   1185 C CA    . PRO A 1 147 ? 113.974 187.042 163.176 1.00 165.82 ? 152 PRO M CA    1 
ATOM   1186 C C     . PRO A 1 147 ? 113.596 188.393 163.763 1.00 165.82 ? 152 PRO M C     1 
ATOM   1187 O O     . PRO A 1 147 ? 112.818 189.153 163.183 1.00 165.82 ? 152 PRO M O     1 
ATOM   1188 C CB    . PRO A 1 147 ? 115.013 187.195 162.059 1.00 165.82 ? 152 PRO M CB    1 
ATOM   1189 C CG    . PRO A 1 147 ? 114.235 187.083 160.791 1.00 165.82 ? 152 PRO M CG    1 
ATOM   1190 C CD    . PRO A 1 147 ? 113.133 186.125 161.081 1.00 165.82 ? 152 PRO M CD    1 
ATOM   1191 N N     . HIS A 1 148 ? 114.160 188.671 164.937 1.00 162.76 ? 153 HIS M N     1 
ATOM   1192 C CA    . HIS A 1 148 ? 114.045 189.934 165.656 1.00 162.76 ? 153 HIS M CA    1 
ATOM   1193 C C     . HIS A 1 148 ? 114.947 189.840 166.877 1.00 162.76 ? 153 HIS M C     1 
ATOM   1194 O O     . HIS A 1 148 ? 115.226 188.747 167.376 1.00 162.76 ? 153 HIS M O     1 
ATOM   1195 C CB    . HIS A 1 148 ? 112.601 190.237 166.076 1.00 162.76 ? 153 HIS M CB    1 
ATOM   1196 C CG    . HIS A 1 148 ? 112.381 191.654 166.510 1.00 162.76 ? 153 HIS M CG    1 
ATOM   1197 N ND1   . HIS A 1 148 ? 112.760 192.122 167.750 1.00 162.76 ? 153 HIS M ND1   1 
ATOM   1198 C CD2   . HIS A 1 148 ? 111.810 192.704 165.873 1.00 162.76 ? 153 HIS M CD2   1 
ATOM   1199 C CE1   . HIS A 1 148 ? 112.442 193.400 167.854 1.00 162.76 ? 153 HIS M CE1   1 
ATOM   1200 N NE2   . HIS A 1 148 ? 111.865 193.778 166.729 1.00 162.76 ? 153 HIS M NE2   1 
ATOM   1201 N N     . ILE A 1 149 ? 115.400 191.000 167.357 1.00 159.99 ? 154 ILE M N     1 
ATOM   1202 C CA    . ILE A 1 149 ? 116.286 191.005 168.514 1.00 159.99 ? 154 ILE M CA    1 
ATOM   1203 C C     . ILE A 1 149 ? 115.557 190.638 169.798 1.00 159.99 ? 154 ILE M C     1 
ATOM   1204 O O     . ILE A 1 149 ? 116.198 190.202 170.760 1.00 159.99 ? 154 ILE M O     1 
ATOM   1205 C CB    . ILE A 1 149 ? 116.981 192.368 168.675 1.00 159.99 ? 154 ILE M CB    1 
ATOM   1206 C CG1   . ILE A 1 149 ? 115.962 193.449 169.023 1.00 159.99 ? 154 ILE M CG1   1 
ATOM   1207 C CG2   . ILE A 1 149 ? 117.758 192.720 167.423 1.00 159.99 ? 154 ILE M CG2   1 
ATOM   1208 C CD1   . ILE A 1 149 ? 116.552 194.584 169.795 1.00 159.99 ? 154 ILE M CD1   1 
ATOM   1209 N N     . PHE A 1 150 ? 114.235 190.813 169.856 1.00 160.24 ? 155 PHE M N     1 
ATOM   1210 C CA    . PHE A 1 150 ? 113.496 190.336 171.021 1.00 160.24 ? 155 PHE M CA    1 
ATOM   1211 C C     . PHE A 1 150 ? 113.649 188.830 171.172 1.00 160.24 ? 155 PHE M C     1 
ATOM   1212 O O     . PHE A 1 150 ? 113.724 188.311 172.294 1.00 160.24 ? 155 PHE M O     1 
ATOM   1213 C CB    . PHE A 1 150 ? 112.019 190.720 170.912 1.00 160.24 ? 155 PHE M CB    1 
ATOM   1214 C CG    . PHE A 1 150 ? 111.757 192.195 171.053 1.00 160.24 ? 155 PHE M CG    1 
ATOM   1215 C CD1   . PHE A 1 150 ? 112.664 193.017 171.696 1.00 160.24 ? 155 PHE M CD1   1 
ATOM   1216 C CD2   . PHE A 1 150 ? 110.594 192.756 170.548 1.00 160.24 ? 155 PHE M CD2   1 
ATOM   1217 C CE1   . PHE A 1 150 ? 112.422 194.373 171.823 1.00 160.24 ? 155 PHE M CE1   1 
ATOM   1218 C CE2   . PHE A 1 150 ? 110.347 194.111 170.671 1.00 160.24 ? 155 PHE M CE2   1 
ATOM   1219 C CZ    . PHE A 1 150 ? 111.262 194.920 171.312 1.00 160.24 ? 155 PHE M CZ    1 
ATOM   1220 N N     . SER A 1 151 ? 113.723 188.117 170.047 1.00 160.42 ? 156 SER M N     1 
ATOM   1221 C CA    . SER A 1 151 ? 113.928 186.675 170.081 1.00 160.42 ? 156 SER M CA    1 
ATOM   1222 C C     . SER A 1 151 ? 115.217 186.329 170.808 1.00 160.42 ? 156 SER M C     1 
ATOM   1223 O O     . SER A 1 151 ? 115.204 185.602 171.804 1.00 160.42 ? 156 SER M O     1 
ATOM   1224 C CB    . SER A 1 151 ? 113.953 186.115 168.660 1.00 160.42 ? 156 SER M CB    1 
ATOM   1225 O OG    . SER A 1 151 ? 115.266 186.150 168.129 1.00 160.42 ? 156 SER M OG    1 
ATOM   1226 N N     . ILE A 1 152 ? 116.344 186.852 170.321 1.00 158.44 ? 157 ILE M N     1 
ATOM   1227 C CA    . ILE A 1 152 ? 117.631 186.523 170.921 1.00 158.44 ? 157 ILE M CA    1 
ATOM   1228 C C     . ILE A 1 152 ? 117.721 187.053 172.344 1.00 158.44 ? 157 ILE M C     1 
ATOM   1229 O O     . ILE A 1 152 ? 118.392 186.452 173.188 1.00 158.44 ? 157 ILE M O     1 
ATOM   1230 C CB    . ILE A 1 152 ? 118.784 187.050 170.050 1.00 158.44 ? 157 ILE M CB    1 
ATOM   1231 C CG1   . ILE A 1 152 ? 118.681 188.561 169.887 1.00 158.44 ? 157 ILE M CG1   1 
ATOM   1232 C CG2   . ILE A 1 152 ? 118.768 186.378 168.691 1.00 158.44 ? 157 ILE M CG2   1 
ATOM   1233 C CD1   . ILE A 1 152 ? 119.652 189.124 168.895 1.00 158.44 ? 157 ILE M CD1   1 
ATOM   1234 N N     . SER A 1 153 ? 117.045 188.163 172.648 1.00 156.99 ? 158 SER M N     1 
ATOM   1235 C CA    . SER A 1 153 ? 117.014 188.646 174.023 1.00 156.99 ? 158 SER M CA    1 
ATOM   1236 C C     . SER A 1 153 ? 116.360 187.618 174.939 1.00 156.99 ? 158 SER M C     1 
ATOM   1237 O O     . SER A 1 153 ? 116.912 187.253 175.985 1.00 156.99 ? 158 SER M O     1 
ATOM   1238 C CB    . SER A 1 153 ? 116.274 189.982 174.088 1.00 156.99 ? 158 SER M CB    1 
ATOM   1239 O OG    . SER A 1 153 ? 116.664 190.848 173.034 1.00 156.99 ? 158 SER M OG    1 
ATOM   1240 N N     . ASP A 1 154 ? 115.185 187.121 174.543 1.00 158.72 ? 159 ASP M N     1 
ATOM   1241 C CA    . ASP A 1 154 ? 114.502 186.108 175.341 1.00 158.72 ? 159 ASP M CA    1 
ATOM   1242 C C     . ASP A 1 154 ? 115.305 184.817 175.399 1.00 158.72 ? 159 ASP M C     1 
ATOM   1243 O O     . ASP A 1 154 ? 115.320 184.135 176.429 1.00 158.72 ? 159 ASP M O     1 
ATOM   1244 C CB    . ASP A 1 154 ? 113.111 185.839 174.770 1.00 158.72 ? 159 ASP M CB    1 
ATOM   1245 C CG    . ASP A 1 154 ? 112.207 185.114 175.748 1.00 158.72 ? 159 ASP M CG    1 
ATOM   1246 O OD1   . ASP A 1 154 ? 112.600 184.046 176.263 1.00 158.72 ? 159 ASP M OD1   1 
ATOM   1247 O OD2   . ASP A 1 154 ? 111.095 185.618 176.007 1.00 158.72 ? 159 ASP M OD2   1 
ATOM   1248 N N     . ASN A 1 155 ? 115.965 184.455 174.297 1.00 156.71 ? 160 ASN M N     1 
ATOM   1249 C CA    . ASN A 1 155 ? 116.764 183.236 174.291 1.00 156.71 ? 160 ASN M CA    1 
ATOM   1250 C C     . ASN A 1 155 ? 117.938 183.355 175.245 1.00 156.71 ? 160 ASN M C     1 
ATOM   1251 O O     . ASN A 1 155 ? 118.250 182.408 175.972 1.00 156.71 ? 160 ASN M O     1 
ATOM   1252 C CB    . ASN A 1 155 ? 117.249 182.913 172.880 1.00 156.71 ? 160 ASN M CB    1 
ATOM   1253 C CG    . ASN A 1 155 ? 116.112 182.694 171.909 1.00 156.71 ? 160 ASN M CG    1 
ATOM   1254 O OD1   . ASN A 1 155 ? 116.083 183.277 170.826 1.00 156.71 ? 160 ASN M OD1   1 
ATOM   1255 N ND2   . ASN A 1 155 ? 115.161 181.852 172.294 1.00 156.71 ? 160 ASN M ND2   1 
ATOM   1256 N N     . ALA A 1 156 ? 118.588 184.518 175.270 1.00 152.89 ? 161 ALA M N     1 
ATOM   1257 C CA    . ALA A 1 156 ? 119.635 184.759 176.251 1.00 152.89 ? 161 ALA M CA    1 
ATOM   1258 C C     . ALA A 1 156 ? 119.083 184.691 177.666 1.00 152.89 ? 161 ALA M C     1 
ATOM   1259 O O     . ALA A 1 156 ? 119.707 184.106 178.557 1.00 152.89 ? 161 ALA M O     1 
ATOM   1260 C CB    . ALA A 1 156 ? 120.285 186.117 175.998 1.00 152.89 ? 161 ALA M CB    1 
ATOM   1261 N N     . TYR A 1 157 ? 117.913 185.288 177.893 1.00 152.93 ? 162 TYR M N     1 
ATOM   1262 C CA    . TYR A 1 157 ? 117.321 185.268 179.225 1.00 152.93 ? 162 TYR M CA    1 
ATOM   1263 C C     . TYR A 1 157 ? 117.084 183.838 179.693 1.00 152.93 ? 162 TYR M C     1 
ATOM   1264 O O     . TYR A 1 157 ? 117.513 183.444 180.785 1.00 152.93 ? 162 TYR M O     1 
ATOM   1265 C CB    . TYR A 1 157 ? 116.012 186.059 179.218 1.00 152.93 ? 162 TYR M CB    1 
ATOM   1266 C CG    . TYR A 1 157 ? 115.412 186.301 180.582 1.00 152.93 ? 162 TYR M CG    1 
ATOM   1267 C CD1   . TYR A 1 157 ? 115.506 187.543 181.189 1.00 152.93 ? 162 TYR M CD1   1 
ATOM   1268 C CD2   . TYR A 1 157 ? 114.745 185.292 181.260 1.00 152.93 ? 162 TYR M CD2   1 
ATOM   1269 C CE1   . TYR A 1 157 ? 114.951 187.773 182.432 1.00 152.93 ? 162 TYR M CE1   1 
ATOM   1270 C CE2   . TYR A 1 157 ? 114.192 185.511 182.501 1.00 152.93 ? 162 TYR M CE2   1 
ATOM   1271 C CZ    . TYR A 1 157 ? 114.298 186.750 183.084 1.00 152.93 ? 162 TYR M CZ    1 
ATOM   1272 O OH    . TYR A 1 157 ? 113.741 186.955 184.324 1.00 152.93 ? 162 TYR M OH    1 
ATOM   1273 N N     . GLN A 1 158 ? 116.402 183.041 178.869 1.00 153.28 ? 163 GLN M N     1 
ATOM   1274 C CA    . GLN A 1 158 ? 116.076 181.676 179.266 1.00 153.28 ? 163 GLN M CA    1 
ATOM   1275 C C     . GLN A 1 158 ? 117.323 180.805 179.339 1.00 153.28 ? 163 GLN M C     1 
ATOM   1276 O O     . GLN A 1 158 ? 117.392 179.894 180.169 1.00 153.28 ? 163 GLN M O     1 
ATOM   1277 C CB    . GLN A 1 158 ? 115.039 181.074 178.318 1.00 153.28 ? 163 GLN M CB    1 
ATOM   1278 C CG    . GLN A 1 158 ? 115.395 181.126 176.866 1.00 153.28 ? 163 GLN M CG    1 
ATOM   1279 C CD    . GLN A 1 158 ? 116.245 179.968 176.444 1.00 153.28 ? 163 GLN M CD    1 
ATOM   1280 O OE1   . GLN A 1 158 ? 116.295 178.934 177.111 1.00 153.28 ? 163 GLN M OE1   1 
ATOM   1281 N NE2   . GLN A 1 158 ? 116.935 180.135 175.332 1.00 153.28 ? 163 GLN M NE2   1 
ATOM   1282 N N     . TYR A 1 159 ? 118.319 181.060 178.485 1.00 150.70 ? 164 TYR M N     1 
ATOM   1283 C CA    . TYR A 1 159 ? 119.601 180.377 178.617 1.00 150.70 ? 164 TYR M CA    1 
ATOM   1284 C C     . TYR A 1 159 ? 120.232 180.667 179.967 1.00 150.70 ? 164 TYR M C     1 
ATOM   1285 O O     . TYR A 1 159 ? 120.735 179.762 180.641 1.00 150.70 ? 164 TYR M O     1 
ATOM   1286 C CB    . TYR A 1 159 ? 120.543 180.800 177.491 1.00 150.70 ? 164 TYR M CB    1 
ATOM   1287 C CG    . TYR A 1 159 ? 120.343 180.089 176.173 1.00 150.70 ? 164 TYR M CG    1 
ATOM   1288 C CD1   . TYR A 1 159 ? 119.708 178.861 176.110 1.00 150.70 ? 164 TYR M CD1   1 
ATOM   1289 C CD2   . TYR A 1 159 ? 120.796 180.651 174.988 1.00 150.70 ? 164 TYR M CD2   1 
ATOM   1290 C CE1   . TYR A 1 159 ? 119.532 178.210 174.905 1.00 150.70 ? 164 TYR M CE1   1 
ATOM   1291 C CE2   . TYR A 1 159 ? 120.620 180.012 173.780 1.00 150.70 ? 164 TYR M CE2   1 
ATOM   1292 C CZ    . TYR A 1 159 ? 119.989 178.791 173.745 1.00 150.70 ? 164 TYR M CZ    1 
ATOM   1293 O OH    . TYR A 1 159 ? 119.816 178.152 172.539 1.00 150.70 ? 164 TYR M OH    1 
ATOM   1294 N N     . MET A 1 160 ? 120.237 181.938 180.365 1.00 150.77 ? 165 MET M N     1 
ATOM   1295 C CA    . MET A 1 160 ? 120.720 182.298 181.690 1.00 150.77 ? 165 MET M CA    1 
ATOM   1296 C C     . MET A 1 160 ? 119.969 181.526 182.759 1.00 150.77 ? 165 MET M C     1 
ATOM   1297 O O     . MET A 1 160 ? 120.571 180.971 183.683 1.00 150.77 ? 165 MET M O     1 
ATOM   1298 C CB    . MET A 1 160 ? 120.569 183.803 181.915 1.00 150.77 ? 165 MET M CB    1 
ATOM   1299 C CG    . MET A 1 160 ? 120.509 184.184 183.385 1.00 150.77 ? 165 MET M CG    1 
ATOM   1300 S SD    . MET A 1 160 ? 120.082 185.906 183.673 1.00 150.77 ? 165 MET M SD    1 
ATOM   1301 C CE    . MET A 1 160 ? 119.864 185.890 185.447 1.00 150.77 ? 165 MET M CE    1 
ATOM   1302 N N     . LEU A 1 161 ? 118.645 181.462 182.632 1.00 151.01 ? 166 LEU M N     1 
ATOM   1303 C CA    . LEU A 1 161 ? 117.841 180.873 183.696 1.00 151.01 ? 166 LEU M CA    1 
ATOM   1304 C C     . LEU A 1 161 ? 117.973 179.357 183.740 1.00 151.01 ? 166 LEU M C     1 
ATOM   1305 O O     . LEU A 1 161 ? 117.774 178.752 184.798 1.00 151.01 ? 166 LEU M O     1 
ATOM   1306 C CB    . LEU A 1 161 ? 116.381 181.286 183.540 1.00 151.01 ? 166 LEU M CB    1 
ATOM   1307 C CG    . LEU A 1 161 ? 115.999 182.555 184.306 1.00 151.01 ? 166 LEU M CG    1 
ATOM   1308 C CD1   . LEU A 1 161 ? 116.172 182.345 185.793 1.00 151.01 ? 166 LEU M CD1   1 
ATOM   1309 C CD2   . LEU A 1 161 ? 116.817 183.748 183.851 1.00 151.01 ? 166 LEU M CD2   1 
ATOM   1310 N N     . THR A 1 162 ? 118.313 178.724 182.621 1.00 150.58 ? 167 THR M N     1 
ATOM   1311 C CA    . THR A 1 162 ? 118.442 177.273 182.638 1.00 150.58 ? 167 THR M CA    1 
ATOM   1312 C C     . THR A 1 162 ? 119.861 176.829 182.981 1.00 150.58 ? 167 THR M C     1 
ATOM   1313 O O     . THR A 1 162 ? 120.046 175.840 183.696 1.00 150.58 ? 167 THR M O     1 
ATOM   1314 C CB    . THR A 1 162 ? 118.000 176.668 181.297 1.00 150.58 ? 167 THR M CB    1 
ATOM   1315 O OG1   . THR A 1 162 ? 118.121 175.241 181.357 1.00 150.58 ? 167 THR M OG1   1 
ATOM   1316 C CG2   . THR A 1 162 ? 118.846 177.183 180.143 1.00 150.58 ? 167 THR M CG2   1 
ATOM   1317 N N     . ASP A 1 163 ? 120.872 177.542 182.487 1.00 150.78 ? 168 ASP M N     1 
ATOM   1318 C CA    . ASP A 1 163 ? 122.249 177.128 182.701 1.00 150.78 ? 168 ASP M CA    1 
ATOM   1319 C C     . ASP A 1 163 ? 122.888 177.795 183.912 1.00 150.78 ? 168 ASP M C     1 
ATOM   1320 O O     . ASP A 1 163 ? 123.989 177.395 184.302 1.00 150.78 ? 168 ASP M O     1 
ATOM   1321 C CB    . ASP A 1 163 ? 123.070 177.416 181.441 1.00 150.78 ? 168 ASP M CB    1 
ATOM   1322 C CG    . ASP A 1 163 ? 124.364 176.631 181.396 1.00 150.78 ? 168 ASP M CG    1 
ATOM   1323 O OD1   . ASP A 1 163 ? 125.244 176.982 180.585 1.00 150.78 ? 168 ASP M OD1   1 
ATOM   1324 O OD2   . ASP A 1 163 ? 124.499 175.661 182.169 1.00 150.78 ? 168 ASP M OD2   1 
ATOM   1325 N N     . ARG A 1 164 ? 122.225 178.786 184.513 1.00 150.23 ? 169 ARG M N     1 
ATOM   1326 C CA    . ARG A 1 164 ? 122.744 179.499 185.678 1.00 150.23 ? 169 ARG M CA    1 
ATOM   1327 C C     . ARG A 1 164 ? 124.103 180.124 185.369 1.00 150.23 ? 169 ARG M C     1 
ATOM   1328 O O     . ARG A 1 164 ? 125.083 179.940 186.095 1.00 150.23 ? 169 ARG M O     1 
ATOM   1329 C CB    . ARG A 1 164 ? 122.820 178.575 186.895 1.00 150.23 ? 169 ARG M CB    1 
ATOM   1330 C CG    . ARG A 1 164 ? 121.505 177.896 187.226 1.00 150.23 ? 169 ARG M CG    1 
ATOM   1331 C CD    . ARG A 1 164 ? 120.383 178.915 187.330 1.00 150.23 ? 169 ARG M CD    1 
ATOM   1332 N NE    . ARG A 1 164 ? 119.096 178.290 187.620 1.00 150.23 ? 169 ARG M NE    1 
ATOM   1333 C CZ    . ARG A 1 164 ? 117.955 178.958 187.746 1.00 150.23 ? 169 ARG M CZ    1 
ATOM   1334 N NH1   . ARG A 1 164 ? 117.936 180.275 187.607 1.00 150.23 ? 169 ARG M NH1   1 
ATOM   1335 N NH2   . ARG A 1 164 ? 116.831 178.308 188.010 1.00 150.23 ? 169 ARG M NH2   1 
ATOM   1336 N N     . GLU A 1 165 ? 124.154 180.869 184.265 1.00 148.00 ? 170 GLU M N     1 
ATOM   1337 C CA    . GLU A 1 165 ? 125.381 181.488 183.791 1.00 148.00 ? 170 GLU M CA    1 
ATOM   1338 C C     . GLU A 1 165 ? 125.052 182.848 183.194 1.00 148.00 ? 170 GLU M C     1 
ATOM   1339 O O     . GLU A 1 165 ? 123.888 183.201 182.998 1.00 148.00 ? 170 GLU M O     1 
ATOM   1340 C CB    . GLU A 1 165 ? 126.090 180.612 182.754 1.00 148.00 ? 170 GLU M CB    1 
ATOM   1341 C CG    . GLU A 1 165 ? 126.560 179.277 183.295 1.00 148.00 ? 170 GLU M CG    1 
ATOM   1342 C CD    . GLU A 1 165 ? 127.308 178.459 182.266 1.00 148.00 ? 170 GLU M CD    1 
ATOM   1343 O OE1   . GLU A 1 165 ? 127.232 178.794 181.067 1.00 148.00 ? 170 GLU M OE1   1 
ATOM   1344 O OE2   . GLU A 1 165 ? 127.972 177.479 182.660 1.00 148.00 ? 170 GLU M OE2   1 
ATOM   1345 N N     . ASN A 1 166 ? 126.096 183.615 182.910 1.00 142.64 ? 171 ASN M N     1 
ATOM   1346 C CA    . ASN A 1 166 ? 125.926 184.903 182.261 1.00 142.64 ? 171 ASN M CA    1 
ATOM   1347 C C     . ASN A 1 166 ? 125.884 184.729 180.749 1.00 142.64 ? 171 ASN M C     1 
ATOM   1348 O O     . ASN A 1 166 ? 126.383 183.744 180.198 1.00 142.64 ? 171 ASN M O     1 
ATOM   1349 C CB    . ASN A 1 166 ? 127.060 185.854 182.642 1.00 142.64 ? 171 ASN M CB    1 
ATOM   1350 C CG    . ASN A 1 166 ? 127.084 186.173 184.122 1.00 142.64 ? 171 ASN M CG    1 
ATOM   1351 O OD1   . ASN A 1 166 ? 126.081 186.582 184.697 1.00 142.64 ? 171 ASN M OD1   1 
ATOM   1352 N ND2   . ASN A 1 166 ? 128.236 185.981 184.748 1.00 142.64 ? 171 ASN M ND2   1 
ATOM   1353 N N     . GLN A 1 167 ? 125.271 185.696 180.077 1.00 142.57 ? 172 GLN M N     1 
ATOM   1354 C CA    . GLN A 1 167 ? 125.237 185.730 178.625 1.00 142.57 ? 172 GLN M CA    1 
ATOM   1355 C C     . GLN A 1 167 ? 125.776 187.075 178.163 1.00 142.57 ? 172 GLN M C     1 
ATOM   1356 O O     . GLN A 1 167 ? 125.877 188.025 178.943 1.00 142.57 ? 172 GLN M O     1 
ATOM   1357 C CB    . GLN A 1 167 ? 123.817 185.497 178.078 1.00 142.57 ? 172 GLN M CB    1 
ATOM   1358 C CG    . GLN A 1 167 ? 123.057 184.349 178.738 1.00 142.57 ? 172 GLN M CG    1 
ATOM   1359 C CD    . GLN A 1 167 ? 123.520 182.974 178.282 1.00 142.57 ? 172 GLN M CD    1 
ATOM   1360 O OE1   . GLN A 1 167 ? 123.727 182.738 177.093 1.00 142.57 ? 172 GLN M OE1   1 
ATOM   1361 N NE2   . GLN A 1 167 ? 123.671 182.055 179.229 1.00 142.57 ? 172 GLN M NE2   1 
ATOM   1362 N N     . SER A 1 168 ? 126.137 187.152 176.886 1.00 140.48 ? 173 SER M N     1 
ATOM   1363 C CA    . SER A 1 168 ? 126.761 188.357 176.361 1.00 140.48 ? 173 SER M CA    1 
ATOM   1364 C C     . SER A 1 168 ? 126.163 188.715 175.012 1.00 140.48 ? 173 SER M C     1 
ATOM   1365 O O     . SER A 1 168 ? 126.116 187.877 174.107 1.00 140.48 ? 173 SER M O     1 
ATOM   1366 C CB    . SER A 1 168 ? 128.276 188.173 176.237 1.00 140.48 ? 173 SER M CB    1 
ATOM   1367 O OG    . SER A 1 168 ? 128.858 187.928 177.506 1.00 140.48 ? 173 SER M OG    1 
ATOM   1368 N N     . ILE A 1 169 ? 125.727 189.963 174.880 1.00 141.09 ? 174 ILE M N     1 
ATOM   1369 C CA    . ILE A 1 169 ? 125.158 190.485 173.643 1.00 141.09 ? 174 ILE M CA    1 
ATOM   1370 C C     . ILE A 1 169 ? 126.198 191.395 173.011 1.00 141.09 ? 174 ILE M C     1 
ATOM   1371 O O     . ILE A 1 169 ? 126.639 192.369 173.632 1.00 141.09 ? 174 ILE M O     1 
ATOM   1372 C CB    . ILE A 1 169 ? 123.848 191.247 173.893 1.00 141.09 ? 174 ILE M CB    1 
ATOM   1373 C CG1   . ILE A 1 169 ? 122.867 190.400 174.708 1.00 141.09 ? 174 ILE M CG1   1 
ATOM   1374 C CG2   . ILE A 1 169 ? 123.229 191.677 172.575 1.00 141.09 ? 174 ILE M CG2   1 
ATOM   1375 C CD1   . ILE A 1 169 ? 122.696 188.989 174.205 1.00 141.09 ? 174 ILE M CD1   1 
ATOM   1376 N N     . LEU A 1 170 ? 126.584 191.089 171.777 1.00 142.48 ? 175 LEU M N     1 
ATOM   1377 C CA    . LEU A 1 170 ? 127.663 191.799 171.096 1.00 142.48 ? 175 LEU M CA    1 
ATOM   1378 C C     . LEU A 1 170 ? 127.080 192.562 169.912 1.00 142.48 ? 175 LEU M C     1 
ATOM   1379 O O     . LEU A 1 170 ? 127.117 192.082 168.776 1.00 142.48 ? 175 LEU M O     1 
ATOM   1380 C CB    . LEU A 1 170 ? 128.753 190.833 170.644 1.00 142.48 ? 175 LEU M CB    1 
ATOM   1381 C CG    . LEU A 1 170 ? 129.689 190.193 171.675 1.00 142.48 ? 175 LEU M CG    1 
ATOM   1382 C CD1   . LEU A 1 170 ? 128.969 189.248 172.626 1.00 142.48 ? 175 LEU M CD1   1 
ATOM   1383 C CD2   . LEU A 1 170 ? 130.825 189.473 170.963 1.00 142.48 ? 175 LEU M CD2   1 
ATOM   1384 N N     . ILE A 1 171 ? 126.578 193.762 170.172 1.00 144.22 ? 176 ILE M N     1 
ATOM   1385 C CA    . ILE A 1 171 ? 126.006 194.607 169.132 1.00 144.22 ? 176 ILE M CA    1 
ATOM   1386 C C     . ILE A 1 171 ? 127.140 195.242 168.338 1.00 144.22 ? 176 ILE M C     1 
ATOM   1387 O O     . ILE A 1 171 ? 128.026 195.891 168.904 1.00 144.22 ? 176 ILE M O     1 
ATOM   1388 C CB    . ILE A 1 171 ? 125.065 195.666 169.738 1.00 144.22 ? 176 ILE M CB    1 
ATOM   1389 C CG1   . ILE A 1 171 ? 124.440 196.531 168.643 1.00 144.22 ? 176 ILE M CG1   1 
ATOM   1390 C CG2   . ILE A 1 171 ? 125.761 196.506 170.797 1.00 144.22 ? 176 ILE M CG2   1 
ATOM   1391 C CD1   . ILE A 1 171 ? 123.345 197.429 169.144 1.00 144.22 ? 176 ILE M CD1   1 
ATOM   1392 N N     . THR A 1 172 ? 127.120 195.042 167.021 1.00 146.33 ? 177 THR M N     1 
ATOM   1393 C CA    . THR A 1 172 ? 128.263 195.343 166.169 1.00 146.33 ? 177 THR M CA    1 
ATOM   1394 C C     . THR A 1 172 ? 127.826 196.229 165.015 1.00 146.33 ? 177 THR M C     1 
ATOM   1395 O O     . THR A 1 172 ? 127.134 195.766 164.104 1.00 146.33 ? 177 THR M O     1 
ATOM   1396 C CB    . THR A 1 172 ? 128.886 194.059 165.629 1.00 146.33 ? 177 THR M CB    1 
ATOM   1397 O OG1   . THR A 1 172 ? 129.194 193.186 166.721 1.00 146.33 ? 177 THR M OG1   1 
ATOM   1398 C CG2   . THR A 1 172 ? 130.163 194.382 164.885 1.00 146.33 ? 177 THR M CG2   1 
ATOM   1399 N N     . GLY A 1 173 ? 128.265 197.479 165.030 1.00 145.64 ? 178 GLY M N     1 
ATOM   1400 C CA    . GLY A 1 173 ? 127.894 198.414 163.985 1.00 145.64 ? 178 GLY M CA    1 
ATOM   1401 C C     . GLY A 1 173 ? 128.599 199.730 164.208 1.00 145.64 ? 178 GLY M C     1 
ATOM   1402 O O     . GLY A 1 173 ? 129.358 199.902 165.167 1.00 145.64 ? 178 GLY M O     1 
ATOM   1403 N N     . GLU A 1 174 ? 128.343 200.662 163.298 1.00 143.34 ? 179 GLU M N     1 
ATOM   1404 C CA    . GLU A 1 174 ? 128.948 201.982 163.369 1.00 143.34 ? 179 GLU M CA    1 
ATOM   1405 C C     . GLU A 1 174 ? 128.088 202.922 164.198 1.00 143.34 ? 179 GLU M C     1 
ATOM   1406 O O     . GLU A 1 174 ? 126.857 202.862 164.161 1.00 143.34 ? 179 GLU M O     1 
ATOM   1407 C CB    . GLU A 1 174 ? 129.139 202.565 161.970 1.00 143.34 ? 179 GLU M CB    1 
ATOM   1408 C CG    . GLU A 1 174 ? 129.848 201.641 161.001 1.00 143.34 ? 179 GLU M CG    1 
ATOM   1409 C CD    . GLU A 1 174 ? 129.957 202.248 159.623 1.00 143.34 ? 179 GLU M CD    1 
ATOM   1410 O OE1   . GLU A 1 174 ? 129.513 203.402 159.453 1.00 143.34 ? 179 GLU M OE1   1 
ATOM   1411 O OE2   . GLU A 1 174 ? 130.486 201.581 158.711 1.00 143.34 ? 179 GLU M OE2   1 
ATOM   1412 N N     . SER A 1 175 ? 128.750 203.798 164.950 1.00 140.91 ? 180 SER M N     1 
ATOM   1413 C CA    . SER A 1 175 ? 128.027 204.813 165.702 1.00 140.91 ? 180 SER M CA    1 
ATOM   1414 C C     . SER A 1 175 ? 127.287 205.734 164.742 1.00 140.91 ? 180 SER M C     1 
ATOM   1415 O O     . SER A 1 175 ? 127.850 206.216 163.756 1.00 140.91 ? 180 SER M O     1 
ATOM   1416 C CB    . SER A 1 175 ? 128.987 205.617 166.582 1.00 140.91 ? 180 SER M CB    1 
ATOM   1417 O OG    . SER A 1 175 ? 128.311 206.661 167.266 1.00 140.91 ? 180 SER M OG    1 
ATOM   1418 N N     . GLY A 1 176 ? 126.013 205.973 165.033 1.00 146.63 ? 181 GLY M N     1 
ATOM   1419 C CA    . GLY A 1 176 ? 125.158 206.689 164.115 1.00 146.63 ? 181 GLY M CA    1 
ATOM   1420 C C     . GLY A 1 176 ? 124.414 205.819 163.128 1.00 146.63 ? 181 GLY M C     1 
ATOM   1421 O O     . GLY A 1 176 ? 123.689 206.355 162.279 1.00 146.63 ? 181 GLY M O     1 
ATOM   1422 N N     . ALA A 1 177 ? 124.578 204.500 163.198 1.00 149.96 ? 182 ALA M N     1 
ATOM   1423 C CA    . ALA A 1 177 ? 123.792 203.569 162.404 1.00 149.96 ? 182 ALA M CA    1 
ATOM   1424 C C     . ALA A 1 177 ? 122.681 202.906 163.210 1.00 149.96 ? 182 ALA M C     1 
ATOM   1425 O O     . ALA A 1 177 ? 122.094 201.924 162.743 1.00 149.96 ? 182 ALA M O     1 
ATOM   1426 C CB    . ALA A 1 177 ? 124.697 202.501 161.787 1.00 149.96 ? 182 ALA M CB    1 
ATOM   1427 N N     . GLY A 1 178 ? 122.384 203.412 164.403 1.00 149.63 ? 183 GLY M N     1 
ATOM   1428 C CA    . GLY A 1 178 ? 121.286 202.913 165.201 1.00 149.63 ? 183 GLY M CA    1 
ATOM   1429 C C     . GLY A 1 178 ? 121.669 202.093 166.410 1.00 149.63 ? 183 GLY M C     1 
ATOM   1430 O O     . GLY A 1 178 ? 120.784 201.487 167.025 1.00 149.63 ? 183 GLY M O     1 
ATOM   1431 N N     . LYS A 1 179 ? 122.951 202.052 166.777 1.00 146.88 ? 184 LYS M N     1 
ATOM   1432 C CA    . LYS A 1 179 ? 123.382 201.205 167.885 1.00 146.88 ? 184 LYS M CA    1 
ATOM   1433 C C     . LYS A 1 179 ? 122.773 201.661 169.204 1.00 146.88 ? 184 LYS M C     1 
ATOM   1434 O O     . LYS A 1 179 ? 122.301 200.839 170.001 1.00 146.88 ? 184 LYS M O     1 
ATOM   1435 C CB    . LYS A 1 179 ? 124.903 201.205 167.978 1.00 146.88 ? 184 LYS M CB    1 
ATOM   1436 C CG    . LYS A 1 179 ? 125.591 200.639 166.765 1.00 146.88 ? 184 LYS M CG    1 
ATOM   1437 C CD    . LYS A 1 179 ? 127.020 200.278 167.094 1.00 146.88 ? 184 LYS M CD    1 
ATOM   1438 C CE    . LYS A 1 179 ? 127.803 201.495 167.573 1.00 146.88 ? 184 LYS M CE    1 
ATOM   1439 N NZ    . LYS A 1 179 ? 129.241 201.171 167.823 1.00 146.88 ? 184 LYS M NZ    1 
ATOM   1440 N N     . THR A 1 180 ? 122.804 202.969 169.459 1.00 149.69 ? 185 THR M N     1 
ATOM   1441 C CA    . THR A 1 180 ? 122.235 203.507 170.687 1.00 149.69 ? 185 THR M CA    1 
ATOM   1442 C C     . THR A 1 180 ? 120.789 203.068 170.858 1.00 149.69 ? 185 THR M C     1 
ATOM   1443 O O     . THR A 1 180 ? 120.415 202.508 171.895 1.00 149.69 ? 185 THR M O     1 
ATOM   1444 C CB    . THR A 1 180 ? 122.326 205.029 170.670 1.00 149.69 ? 185 THR M CB    1 
ATOM   1445 O OG1   . THR A 1 180 ? 121.312 205.550 169.803 1.00 149.69 ? 185 THR M OG1   1 
ATOM   1446 C CG2   . THR A 1 180 ? 123.688 205.471 170.161 1.00 149.69 ? 185 THR M CG2   1 
ATOM   1447 N N     . VAL A 1 181 ? 119.961 203.300 169.839 1.00 153.06 ? 186 VAL M N     1 
ATOM   1448 C CA    . VAL A 1 181 ? 118.539 203.011 169.977 1.00 153.06 ? 186 VAL M CA    1 
ATOM   1449 C C     . VAL A 1 181 ? 118.288 201.509 169.965 1.00 153.06 ? 186 VAL M C     1 
ATOM   1450 O O     . VAL A 1 181 ? 117.324 201.031 170.576 1.00 153.06 ? 186 VAL M O     1 
ATOM   1451 C CB    . VAL A 1 181 ? 117.740 203.747 168.884 1.00 153.06 ? 186 VAL M CB    1 
ATOM   1452 C CG1   . VAL A 1 181 ? 117.867 203.043 167.541 1.00 153.06 ? 186 VAL M CG1   1 
ATOM   1453 C CG2   . VAL A 1 181 ? 116.280 203.901 169.300 1.00 153.06 ? 186 VAL M CG2   1 
ATOM   1454 N N     . ASN A 1 182 ? 119.152 200.737 169.305 1.00 152.27 ? 187 ASN M N     1 
ATOM   1455 C CA    . ASN A 1 182 ? 119.030 199.286 169.373 1.00 152.27 ? 187 ASN M CA    1 
ATOM   1456 C C     . ASN A 1 182 ? 119.233 198.802 170.802 1.00 152.27 ? 187 ASN M C     1 
ATOM   1457 O O     . ASN A 1 182 ? 118.426 198.032 171.334 1.00 152.27 ? 187 ASN M O     1 
ATOM   1458 C CB    . ASN A 1 182 ? 120.036 198.629 168.428 1.00 152.27 ? 187 ASN M CB    1 
ATOM   1459 C CG    . ASN A 1 182 ? 119.713 197.173 168.151 1.00 152.27 ? 187 ASN M CG    1 
ATOM   1460 O OD1   . ASN A 1 182 ? 119.644 196.354 169.065 1.00 152.27 ? 187 ASN M OD1   1 
ATOM   1461 N ND2   . ASN A 1 182 ? 119.531 196.841 166.880 1.00 152.27 ? 187 ASN M ND2   1 
ATOM   1462 N N     . THR A 1 183 ? 120.303 199.264 171.449 1.00 152.10 ? 188 THR M N     1 
ATOM   1463 C CA    . THR A 1 183 ? 120.513 198.920 172.850 1.00 152.10 ? 188 THR M CA    1 
ATOM   1464 C C     . THR A 1 183 ? 119.397 199.460 173.734 1.00 152.10 ? 188 THR M C     1 
ATOM   1465 O O     . THR A 1 183 ? 119.048 198.837 174.743 1.00 152.10 ? 188 THR M O     1 
ATOM   1466 C CB    . THR A 1 183 ? 121.863 199.449 173.327 1.00 152.10 ? 188 THR M CB    1 
ATOM   1467 O OG1   . THR A 1 183 ? 122.075 200.765 172.798 1.00 152.10 ? 188 THR M OG1   1 
ATOM   1468 C CG2   . THR A 1 183 ? 122.980 198.533 172.871 1.00 152.10 ? 188 THR M CG2   1 
ATOM   1469 N N     . LYS A 1 184 ? 118.831 200.614 173.378 1.00 152.92 ? 189 LYS M N     1 
ATOM   1470 C CA    . LYS A 1 184 ? 117.729 201.167 174.158 1.00 152.92 ? 189 LYS M CA    1 
ATOM   1471 C C     . LYS A 1 184 ? 116.524 200.239 174.117 1.00 152.92 ? 189 LYS M C     1 
ATOM   1472 O O     . LYS A 1 184 ? 115.901 199.959 175.146 1.00 152.92 ? 189 LYS M O     1 
ATOM   1473 C CB    . LYS A 1 184 ? 117.358 202.557 173.635 1.00 152.92 ? 189 LYS M CB    1 
ATOM   1474 C CG    . LYS A 1 184 ? 116.362 203.316 174.512 1.00 152.92 ? 189 LYS M CG    1 
ATOM   1475 C CD    . LYS A 1 184 ? 114.913 203.089 174.104 1.00 152.92 ? 189 LYS M CD    1 
ATOM   1476 C CE    . LYS A 1 184 ? 114.571 203.762 172.791 1.00 152.92 ? 189 LYS M CE    1 
ATOM   1477 N NZ    . LYS A 1 184 ? 113.143 203.533 172.424 1.00 152.92 ? 189 LYS M NZ    1 
ATOM   1478 N N     . ARG A 1 185 ? 116.168 199.760 172.927 1.00 156.29 ? 190 ARG M N     1 
ATOM   1479 C CA    . ARG A 1 185 ? 115.037 198.845 172.842 1.00 156.29 ? 190 ARG M CA    1 
ATOM   1480 C C     . ARG A 1 185 ? 115.362 197.502 173.485 1.00 156.29 ? 190 ARG M C     1 
ATOM   1481 O O     . ARG A 1 185 ? 114.465 196.844 174.027 1.00 156.29 ? 190 ARG M O     1 
ATOM   1482 C CB    . ARG A 1 185 ? 114.592 198.676 171.389 1.00 156.29 ? 190 ARG M CB    1 
ATOM   1483 C CG    . ARG A 1 185 ? 115.502 197.831 170.532 1.00 156.29 ? 190 ARG M CG    1 
ATOM   1484 C CD    . ARG A 1 185 ? 115.086 197.870 169.068 1.00 156.29 ? 190 ARG M CD    1 
ATOM   1485 N NE    . ARG A 1 185 ? 115.489 199.114 168.417 1.00 156.29 ? 190 ARG M NE    1 
ATOM   1486 C CZ    . ARG A 1 185 ? 114.687 200.160 168.241 1.00 156.29 ? 190 ARG M CZ    1 
ATOM   1487 N NH1   . ARG A 1 185 ? 113.432 200.112 168.665 1.00 156.29 ? 190 ARG M NH1   1 
ATOM   1488 N NH2   . ARG A 1 185 ? 115.138 201.250 167.638 1.00 156.29 ? 190 ARG M NH2   1 
ATOM   1489 N N     . VAL A 1 186 ? 116.635 197.098 173.475 1.00 153.44 ? 191 VAL M N     1 
ATOM   1490 C CA    . VAL A 1 186 ? 117.037 195.907 174.222 1.00 153.44 ? 191 VAL M CA    1 
ATOM   1491 C C     . VAL A 1 186 ? 116.739 196.084 175.704 1.00 153.44 ? 191 VAL M C     1 
ATOM   1492 O O     . VAL A 1 186 ? 116.127 195.218 176.343 1.00 153.44 ? 191 VAL M O     1 
ATOM   1493 C CB    . VAL A 1 186 ? 118.525 195.592 173.993 1.00 153.44 ? 191 VAL M CB    1 
ATOM   1494 C CG1   . VAL A 1 186 ? 118.901 194.356 174.760 1.00 153.44 ? 191 VAL M CG1   1 
ATOM   1495 C CG2   . VAL A 1 186 ? 118.796 195.362 172.532 1.00 153.44 ? 191 VAL M CG2   1 
ATOM   1496 N N     . ILE A 1 187 ? 117.184 197.204 176.278 1.00 152.38 ? 192 ILE M N     1 
ATOM   1497 C CA    . ILE A 1 187 ? 117.007 197.386 177.714 1.00 152.38 ? 192 ILE M CA    1 
ATOM   1498 C C     . ILE A 1 187 ? 115.534 197.582 178.044 1.00 152.38 ? 192 ILE M C     1 
ATOM   1499 O O     . ILE A 1 187 ? 115.074 197.172 179.117 1.00 152.38 ? 192 ILE M O     1 
ATOM   1500 C CB    . ILE A 1 187 ? 117.877 198.546 178.241 1.00 152.38 ? 192 ILE M CB    1 
ATOM   1501 C CG1   . ILE A 1 187 ? 117.411 199.888 177.679 1.00 152.38 ? 192 ILE M CG1   1 
ATOM   1502 C CG2   . ILE A 1 187 ? 119.345 198.304 177.912 1.00 152.38 ? 192 ILE M CG2   1 
ATOM   1503 C CD1   . ILE A 1 187 ? 118.329 201.044 177.986 1.00 152.38 ? 192 ILE M CD1   1 
ATOM   1504 N N     . GLN A 1 188 ? 114.762 198.170 177.126 1.00 153.17 ? 193 GLN M N     1 
ATOM   1505 C CA    . GLN A 1 188 ? 113.318 198.233 177.324 1.00 153.17 ? 193 GLN M CA    1 
ATOM   1506 C C     . GLN A 1 188 ? 112.715 196.840 177.397 1.00 153.17 ? 193 GLN M C     1 
ATOM   1507 O O     . GLN A 1 188 ? 111.929 196.545 178.300 1.00 153.17 ? 193 GLN M O     1 
ATOM   1508 C CB    . GLN A 1 188 ? 112.645 199.037 176.215 1.00 153.17 ? 193 GLN M CB    1 
ATOM   1509 C CG    . GLN A 1 188 ? 112.821 200.528 176.333 1.00 153.17 ? 193 GLN M CG    1 
ATOM   1510 C CD    . GLN A 1 188 ? 112.027 201.277 175.291 1.00 153.17 ? 193 GLN M CD    1 
ATOM   1511 O OE1   . GLN A 1 188 ? 111.415 200.672 174.413 1.00 153.17 ? 193 GLN M OE1   1 
ATOM   1512 N NE2   . GLN A 1 188 ? 112.012 202.601 175.394 1.00 153.17 ? 193 GLN M NE2   1 
ATOM   1513 N N     . TYR A 1 189 ? 113.055 195.976 176.441 1.00 156.36 ? 194 TYR M N     1 
ATOM   1514 C CA    . TYR A 1 189 ? 112.518 194.621 176.461 1.00 156.36 ? 194 TYR M CA    1 
ATOM   1515 C C     . TYR A 1 189 ? 112.920 193.889 177.735 1.00 156.36 ? 194 TYR M C     1 
ATOM   1516 O O     . TYR A 1 189 ? 112.134 193.114 178.294 1.00 156.36 ? 194 TYR M O     1 
ATOM   1517 C CB    . TYR A 1 189 ? 112.992 193.848 175.233 1.00 156.36 ? 194 TYR M CB    1 
ATOM   1518 C CG    . TYR A 1 189 ? 112.622 192.387 175.286 1.00 156.36 ? 194 TYR M CG    1 
ATOM   1519 C CD1   . TYR A 1 189 ? 111.365 191.962 174.892 1.00 156.36 ? 194 TYR M CD1   1 
ATOM   1520 C CD2   . TYR A 1 189 ? 113.520 191.436 175.748 1.00 156.36 ? 194 TYR M CD2   1 
ATOM   1521 C CE1   . TYR A 1 189 ? 111.013 190.637 174.950 1.00 156.36 ? 194 TYR M CE1   1 
ATOM   1522 C CE2   . TYR A 1 189 ? 113.176 190.107 175.804 1.00 156.36 ? 194 TYR M CE2   1 
ATOM   1523 C CZ    . TYR A 1 189 ? 111.922 189.715 175.404 1.00 156.36 ? 194 TYR M CZ    1 
ATOM   1524 O OH    . TYR A 1 189 ? 111.565 188.392 175.459 1.00 156.36 ? 194 TYR M OH    1 
ATOM   1525 N N     . PHE A 1 190 ? 114.147 194.115 178.203 1.00 153.86 ? 195 PHE M N     1 
ATOM   1526 C CA    . PHE A 1 190 ? 114.596 193.450 179.422 1.00 153.86 ? 195 PHE M CA    1 
ATOM   1527 C C     . PHE A 1 190 ? 113.829 193.949 180.637 1.00 153.86 ? 195 PHE M C     1 
ATOM   1528 O O     . PHE A 1 190 ? 113.456 193.157 181.510 1.00 153.86 ? 195 PHE M O     1 
ATOM   1529 C CB    . PHE A 1 190 ? 116.094 193.653 179.605 1.00 153.86 ? 195 PHE M CB    1 
ATOM   1530 C CG    . PHE A 1 190 ? 116.923 192.814 178.690 1.00 153.86 ? 195 PHE M CG    1 
ATOM   1531 C CD1   . PHE A 1 190 ? 116.407 191.650 178.151 1.00 153.86 ? 195 PHE M CD1   1 
ATOM   1532 C CD2   . PHE A 1 190 ? 118.213 193.187 178.363 1.00 153.86 ? 195 PHE M CD2   1 
ATOM   1533 C CE1   . PHE A 1 190 ? 117.164 190.872 177.307 1.00 153.86 ? 195 PHE M CE1   1 
ATOM   1534 C CE2   . PHE A 1 190 ? 118.976 192.411 177.523 1.00 153.86 ? 195 PHE M CE2   1 
ATOM   1535 C CZ    . PHE A 1 190 ? 118.451 191.256 176.989 1.00 153.86 ? 195 PHE M CZ    1 
ATOM   1536 N N     . ALA A 1 191 ? 113.576 195.257 180.712 1.00 153.04 ? 196 ALA M N     1 
ATOM   1537 C CA    . ALA A 1 191 ? 112.734 195.778 181.782 1.00 153.04 ? 196 ALA M CA    1 
ATOM   1538 C C     . ALA A 1 191 ? 111.324 195.211 181.689 1.00 153.04 ? 196 ALA M C     1 
ATOM   1539 O O     . ALA A 1 191 ? 110.692 194.922 182.712 1.00 153.04 ? 196 ALA M O     1 
ATOM   1540 C CB    . ALA A 1 191 ? 112.704 197.306 181.734 1.00 153.04 ? 196 ALA M CB    1 
ATOM   1541 N N     . VAL A 1 192 ? 110.821 195.041 180.466 1.00 154.26 ? 197 VAL M N     1 
ATOM   1542 C CA    . VAL A 1 192 ? 109.469 194.526 180.265 1.00 154.26 ? 197 VAL M CA    1 
ATOM   1543 C C     . VAL A 1 192 ? 109.361 193.109 180.801 1.00 154.26 ? 197 VAL M C     1 
ATOM   1544 O O     . VAL A 1 192 ? 108.454 192.783 181.575 1.00 154.26 ? 197 VAL M O     1 
ATOM   1545 C CB    . VAL A 1 192 ? 109.091 194.591 178.775 1.00 154.26 ? 197 VAL M CB    1 
ATOM   1546 C CG1   . VAL A 1 192 ? 107.969 193.612 178.469 1.00 154.26 ? 197 VAL M CG1   1 
ATOM   1547 C CG2   . VAL A 1 192 ? 108.692 196.000 178.396 1.00 154.26 ? 197 VAL M CG2   1 
ATOM   1548 N N     . ILE A 1 193 ? 110.290 192.243 180.396 1.00 154.30 ? 198 ILE M N     1 
ATOM   1549 C CA    . ILE A 1 193 ? 110.303 190.878 180.904 1.00 154.30 ? 198 ILE M CA    1 
ATOM   1550 C C     . ILE A 1 193 ? 110.759 190.810 182.351 1.00 154.30 ? 198 ILE M C     1 
ATOM   1551 O O     . ILE A 1 193 ? 110.681 189.740 182.964 1.00 154.30 ? 198 ILE M O     1 
ATOM   1552 C CB    . ILE A 1 193 ? 111.188 189.984 180.013 1.00 154.30 ? 198 ILE M CB    1 
ATOM   1553 C CG1   . ILE A 1 193 ? 112.650 190.418 180.098 1.00 154.30 ? 198 ILE M CG1   1 
ATOM   1554 C CG2   . ILE A 1 193 ? 110.708 190.040 178.576 1.00 154.30 ? 198 ILE M CG2   1 
ATOM   1555 C CD1   . ILE A 1 193 ? 113.561 189.609 179.223 1.00 154.30 ? 198 ILE M CD1   1 
ATOM   1556 N N     . ALA A 1 194 ? 111.236 191.923 182.902 1.00 152.22 ? 199 ALA M N     1 
ATOM   1557 C CA    . ALA A 1 194 ? 111.557 192.041 184.320 1.00 152.22 ? 199 ALA M CA    1 
ATOM   1558 C C     . ALA A 1 194 ? 112.567 190.994 184.777 1.00 152.22 ? 199 ALA M C     1 
ATOM   1559 O O     . ALA A 1 194 ? 113.603 191.329 185.350 1.00 152.22 ? 199 ALA M O     1 
ATOM   1560 C CB    . ALA A 1 194 ? 110.284 191.955 185.159 1.00 152.22 ? 199 ALA M CB    1 
ATOM   1561 N N     . LEU A 1 211 ? 115.859 200.855 185.012 1.00 140.93 ? 216 LEU M N     1 
ATOM   1562 C CA    . LEU A 1 211 ? 116.866 201.883 185.234 1.00 140.93 ? 216 LEU M CA    1 
ATOM   1563 C C     . LEU A 1 211 ? 117.381 202.420 183.902 1.00 140.93 ? 216 LEU M C     1 
ATOM   1564 O O     . LEU A 1 211 ? 118.420 203.078 183.837 1.00 140.93 ? 216 LEU M O     1 
ATOM   1565 C CB    . LEU A 1 211 ? 118.014 201.330 186.082 1.00 140.93 ? 216 LEU M CB    1 
ATOM   1566 C CG    . LEU A 1 211 ? 117.624 201.030 187.532 1.00 140.93 ? 216 LEU M CG    1 
ATOM   1567 C CD1   . LEU A 1 211 ? 118.628 200.102 188.202 1.00 140.93 ? 216 LEU M CD1   1 
ATOM   1568 C CD2   . LEU A 1 211 ? 117.481 202.326 188.314 1.00 140.93 ? 216 LEU M CD2   1 
ATOM   1569 N N     . GLU A 1 212 ? 116.621 202.137 182.843 1.00 142.62 ? 217 GLU M N     1 
ATOM   1570 C CA    . GLU A 1 212 ? 117.000 202.570 181.502 1.00 142.62 ? 217 GLU M CA    1 
ATOM   1571 C C     . GLU A 1 212 ? 117.091 204.088 181.409 1.00 142.62 ? 217 GLU M C     1 
ATOM   1572 O O     . GLU A 1 212 ? 117.983 204.626 180.737 1.00 142.62 ? 217 GLU M O     1 
ATOM   1573 C CB    . GLU A 1 212 ? 115.988 202.032 180.496 1.00 142.62 ? 217 GLU M CB    1 
ATOM   1574 C CG    . GLU A 1 212 ? 114.551 202.234 180.937 1.00 142.62 ? 217 GLU M CG    1 
ATOM   1575 C CD    . GLU A 1 212 ? 113.562 201.480 180.082 1.00 142.62 ? 217 GLU M CD    1 
ATOM   1576 O OE1   . GLU A 1 212 ? 114.003 200.689 179.225 1.00 142.62 ? 217 GLU M OE1   1 
ATOM   1577 O OE2   . GLU A 1 212 ? 112.343 201.683 180.266 1.00 142.62 ? 217 GLU M OE2   1 
ATOM   1578 N N     . ASP A 1 213 ? 116.163 204.792 182.063 1.00 139.77 ? 218 ASP M N     1 
ATOM   1579 C CA    . ASP A 1 213 ? 116.176 206.250 182.040 1.00 139.77 ? 218 ASP M CA    1 
ATOM   1580 C C     . ASP A 1 213 ? 117.498 206.790 182.555 1.00 139.77 ? 218 ASP M C     1 
ATOM   1581 O O     . ASP A 1 213 ? 118.048 207.744 181.997 1.00 139.77 ? 218 ASP M O     1 
ATOM   1582 C CB    . ASP A 1 213 ? 115.021 206.797 182.876 1.00 139.77 ? 218 ASP M CB    1 
ATOM   1583 C CG    . ASP A 1 213 ? 113.689 206.692 182.172 1.00 139.77 ? 218 ASP M CG    1 
ATOM   1584 O OD1   . ASP A 1 213 ? 112.653 206.713 182.867 1.00 139.77 ? 218 ASP M OD1   1 
ATOM   1585 O OD2   . ASP A 1 213 ? 113.676 206.590 180.927 1.00 139.77 ? 218 ASP M OD2   1 
ATOM   1586 N N     . GLN A 1 214 ? 118.033 206.172 183.609 1.00 138.59 ? 219 GLN M N     1 
ATOM   1587 C CA    . GLN A 1 214 ? 119.319 206.586 184.157 1.00 138.59 ? 219 GLN M CA    1 
ATOM   1588 C C     . GLN A 1 214 ? 120.453 206.314 183.175 1.00 138.59 ? 219 GLN M C     1 
ATOM   1589 O O     . GLN A 1 214 ? 121.385 207.119 183.052 1.00 138.59 ? 219 GLN M O     1 
ATOM   1590 C CB    . GLN A 1 214 ? 119.563 205.863 185.482 1.00 138.59 ? 219 GLN M CB    1 
ATOM   1591 C CG    . GLN A 1 214 ? 118.583 206.224 186.597 1.00 138.59 ? 219 GLN M CG    1 
ATOM   1592 C CD    . GLN A 1 214 ? 117.208 205.592 186.425 1.00 138.59 ? 219 GLN M CD    1 
ATOM   1593 O OE1   . GLN A 1 214 ? 116.914 204.987 185.399 1.00 138.59 ? 219 GLN M OE1   1 
ATOM   1594 N NE2   . GLN A 1 214 ? 116.361 205.736 187.437 1.00 138.59 ? 219 GLN M NE2   1 
ATOM   1595 N N     . ILE A 1 215 ? 120.391 205.182 182.472 1.00 137.34 ? 220 ILE M N     1 
ATOM   1596 C CA    . ILE A 1 215 ? 121.392 204.874 181.454 1.00 137.34 ? 220 ILE M CA    1 
ATOM   1597 C C     . ILE A 1 215 ? 121.427 205.972 180.404 1.00 137.34 ? 220 ILE M C     1 
ATOM   1598 O O     . ILE A 1 215 ? 122.482 206.548 180.110 1.00 137.34 ? 220 ILE M O     1 
ATOM   1599 C CB    . ILE A 1 215 ? 121.101 203.504 180.816 1.00 137.34 ? 220 ILE M CB    1 
ATOM   1600 C CG1   . ILE A 1 215 ? 121.521 202.366 181.746 1.00 137.34 ? 220 ILE M CG1   1 
ATOM   1601 C CG2   . ILE A 1 215 ? 121.792 203.384 179.470 1.00 137.34 ? 220 ILE M CG2   1 
ATOM   1602 C CD1   . ILE A 1 215 ? 121.246 200.995 181.177 1.00 137.34 ? 220 ILE M CD1   1 
ATOM   1603 N N     . ILE A 1 216 ? 120.266 206.283 179.826 1.00 138.02 ? 221 ILE M N     1 
ATOM   1604 C CA    . ILE A 1 216 ? 120.226 207.298 178.780 1.00 138.02 ? 221 ILE M CA    1 
ATOM   1605 C C     . ILE A 1 216 ? 120.591 208.666 179.339 1.00 138.02 ? 221 ILE M C     1 
ATOM   1606 O O     . ILE A 1 216 ? 121.176 209.496 178.633 1.00 138.02 ? 221 ILE M O     1 
ATOM   1607 C CB    . ILE A 1 216 ? 118.842 207.314 178.104 1.00 138.02 ? 221 ILE M CB    1 
ATOM   1608 C CG1   . ILE A 1 216 ? 118.343 205.887 177.845 1.00 138.02 ? 221 ILE M CG1   1 
ATOM   1609 C CG2   . ILE A 1 216 ? 118.889 208.118 176.810 1.00 138.02 ? 221 ILE M CG2   1 
ATOM   1610 C CD1   . ILE A 1 216 ? 119.268 205.044 176.982 1.00 138.02 ? 221 ILE M CD1   1 
ATOM   1611 N N     . GLN A 1 217 ? 120.273 208.922 180.610 1.00 136.11 ? 222 GLN M N     1 
ATOM   1612 C CA    . GLN A 1 217 ? 120.554 210.222 181.205 1.00 136.11 ? 222 GLN M CA    1 
ATOM   1613 C C     . GLN A 1 217 ? 122.047 210.433 181.398 1.00 136.11 ? 222 GLN M C     1 
ATOM   1614 O O     . GLN A 1 217 ? 122.562 211.530 181.154 1.00 136.11 ? 222 GLN M O     1 
ATOM   1615 C CB    . GLN A 1 217 ? 119.820 210.345 182.540 1.00 136.11 ? 222 GLN M CB    1 
ATOM   1616 C CG    . GLN A 1 217 ? 119.953 211.698 183.219 1.00 136.11 ? 222 GLN M CG    1 
ATOM   1617 C CD    . GLN A 1 217 ? 119.307 211.715 184.590 1.00 136.11 ? 222 GLN M CD    1 
ATOM   1618 O OE1   . GLN A 1 217 ? 118.749 212.726 185.015 1.00 136.11 ? 222 GLN M OE1   1 
ATOM   1619 N NE2   . GLN A 1 217 ? 119.377 210.587 185.290 1.00 136.11 ? 222 GLN M NE2   1 
ATOM   1620 N N     . ALA A 1 218 ? 122.756 209.403 181.844 1.00 134.15 ? 223 ALA M N     1 
ATOM   1621 C CA    . ALA A 1 218 ? 124.195 209.521 182.019 1.00 134.15 ? 223 ALA M CA    1 
ATOM   1622 C C     . ALA A 1 218 ? 124.966 209.271 180.730 1.00 134.15 ? 223 ALA M C     1 
ATOM   1623 O O     . ALA A 1 218 ? 126.182 209.486 180.704 1.00 134.15 ? 223 ALA M O     1 
ATOM   1624 C CB    . ALA A 1 218 ? 124.672 208.559 183.106 1.00 134.15 ? 223 ALA M CB    1 
ATOM   1625 N N     . ASN A 1 219 ? 124.292 208.825 179.672 1.00 131.55 ? 224 ASN M N     1 
ATOM   1626 C CA    . ASN A 1 219 ? 124.981 208.581 178.408 1.00 131.55 ? 224 ASN M CA    1 
ATOM   1627 C C     . ASN A 1 219 ? 125.697 209.797 177.822 1.00 131.55 ? 224 ASN M C     1 
ATOM   1628 O O     . ASN A 1 219 ? 126.824 209.622 177.330 1.00 131.55 ? 224 ASN M O     1 
ATOM   1629 C CB    . ASN A 1 219 ? 123.983 207.998 177.403 1.00 131.55 ? 224 ASN M CB    1 
ATOM   1630 C CG    . ASN A 1 219 ? 124.629 207.641 176.091 1.00 131.55 ? 224 ASN M CG    1 
ATOM   1631 O OD1   . ASN A 1 219 ? 124.372 208.273 175.068 1.00 131.55 ? 224 ASN M OD1   1 
ATOM   1632 N ND2   . ASN A 1 219 ? 125.484 206.626 176.110 1.00 131.55 ? 224 ASN M ND2   1 
ATOM   1633 N N     . PRO A 1 220 ? 125.137 211.014 177.815 1.00 130.03 ? 225 PRO M N     1 
ATOM   1634 C CA    . PRO A 1 220 ? 125.875 212.141 177.215 1.00 130.03 ? 225 PRO M CA    1 
ATOM   1635 C C     . PRO A 1 220 ? 127.262 212.349 177.796 1.00 130.03 ? 225 PRO M C     1 
ATOM   1636 O O     . PRO A 1 220 ? 128.150 212.838 177.087 1.00 130.03 ? 225 PRO M O     1 
ATOM   1637 C CB    . PRO A 1 220 ? 124.967 213.345 177.496 1.00 130.03 ? 225 PRO M CB    1 
ATOM   1638 C CG    . PRO A 1 220 ? 123.622 212.775 177.579 1.00 130.03 ? 225 PRO M CG    1 
ATOM   1639 C CD    . PRO A 1 220 ? 123.781 211.424 178.220 1.00 130.03 ? 225 PRO M CD    1 
ATOM   1640 N N     . ALA A 1 221 ? 127.484 211.975 179.059 1.00 127.57 ? 226 ALA M N     1 
ATOM   1641 C CA    . ALA A 1 221 ? 128.820 212.076 179.640 1.00 127.57 ? 226 ALA M CA    1 
ATOM   1642 C C     . ALA A 1 221 ? 129.814 211.205 178.884 1.00 127.57 ? 226 ALA M C     1 
ATOM   1643 O O     . ALA A 1 221 ? 130.888 211.670 178.482 1.00 127.57 ? 226 ALA M O     1 
ATOM   1644 C CB    . ALA A 1 221 ? 128.778 211.685 181.116 1.00 127.57 ? 226 ALA M CB    1 
ATOM   1645 N N     . LEU A 1 222 ? 129.475 209.930 178.689 1.00 125.66 ? 227 LEU M N     1 
ATOM   1646 C CA    . LEU A 1 222 ? 130.351 209.045 177.931 1.00 125.66 ? 227 LEU M CA    1 
ATOM   1647 C C     . LEU A 1 222 ? 130.460 209.498 176.484 1.00 125.66 ? 227 LEU M C     1 
ATOM   1648 O O     . LEU A 1 222 ? 131.537 209.432 175.885 1.00 125.66 ? 227 LEU M O     1 
ATOM   1649 C CB    . LEU A 1 222 ? 129.839 207.610 178.004 1.00 125.66 ? 227 LEU M CB    1 
ATOM   1650 C CG    . LEU A 1 222 ? 129.454 207.111 179.395 1.00 125.66 ? 227 LEU M CG    1 
ATOM   1651 C CD1   . LEU A 1 222 ? 129.001 205.666 179.335 1.00 125.66 ? 227 LEU M CD1   1 
ATOM   1652 C CD2   . LEU A 1 222 ? 130.607 207.267 180.360 1.00 125.66 ? 227 LEU M CD2   1 
ATOM   1653 N N     . GLU A 1 223 ? 129.351 209.962 175.906 1.00 127.54 ? 228 GLU M N     1 
ATOM   1654 C CA    . GLU A 1 223 ? 129.391 210.466 174.538 1.00 127.54 ? 228 GLU M CA    1 
ATOM   1655 C C     . GLU A 1 223 ? 130.387 211.606 174.410 1.00 127.54 ? 228 GLU M C     1 
ATOM   1656 O O     . GLU A 1 223 ? 131.050 211.753 173.378 1.00 127.54 ? 228 GLU M O     1 
ATOM   1657 C CB    . GLU A 1 223 ? 128.000 210.926 174.102 1.00 127.54 ? 228 GLU M CB    1 
ATOM   1658 C CG    . GLU A 1 223 ? 126.914 209.872 174.216 1.00 127.54 ? 228 GLU M CG    1 
ATOM   1659 C CD    . GLU A 1 223 ? 127.217 208.624 173.414 1.00 127.54 ? 228 GLU M CD    1 
ATOM   1660 O OE1   . GLU A 1 223 ? 127.890 207.717 173.946 1.00 127.54 ? 228 GLU M OE1   1 
ATOM   1661 O OE2   . GLU A 1 223 ? 126.783 208.551 172.247 1.00 127.54 ? 228 GLU M OE2   1 
ATOM   1662 N N     . ALA A 1 224 ? 130.497 212.434 175.444 1.00 123.70 ? 229 ALA M N     1 
ATOM   1663 C CA    . ALA A 1 224 ? 131.507 213.480 175.426 1.00 123.70 ? 229 ALA M CA    1 
ATOM   1664 C C     . ALA A 1 224 ? 132.898 212.888 175.580 1.00 123.70 ? 229 ALA M C     1 
ATOM   1665 O O     . ALA A 1 224 ? 133.753 213.045 174.702 1.00 123.70 ? 229 ALA M O     1 
ATOM   1666 C CB    . ALA A 1 224 ? 131.233 214.493 176.533 1.00 123.70 ? 229 ALA M CB    1 
ATOM   1667 N N     . PHE A 1 225 ? 133.122 212.154 176.664 1.00 120.85 ? 230 PHE M N     1 
ATOM   1668 C CA    . PHE A 1 225 ? 134.466 211.791 177.087 1.00 120.85 ? 230 PHE M CA    1 
ATOM   1669 C C     . PHE A 1 225 ? 135.043 210.603 176.336 1.00 120.85 ? 230 PHE M C     1 
ATOM   1670 O O     . PHE A 1 225 ? 136.178 210.211 176.618 1.00 120.85 ? 230 PHE M O     1 
ATOM   1671 C CB    . PHE A 1 225 ? 134.489 211.507 178.590 1.00 120.85 ? 230 PHE M CB    1 
ATOM   1672 C CG    . PHE A 1 225 ? 134.583 212.741 179.436 1.00 120.85 ? 230 PHE M CG    1 
ATOM   1673 C CD1   . PHE A 1 225 ? 133.947 213.908 179.056 1.00 120.85 ? 230 PHE M CD1   1 
ATOM   1674 C CD2   . PHE A 1 225 ? 135.319 212.742 180.600 1.00 120.85 ? 230 PHE M CD2   1 
ATOM   1675 C CE1   . PHE A 1 225 ? 134.036 215.045 179.824 1.00 120.85 ? 230 PHE M CE1   1 
ATOM   1676 C CE2   . PHE A 1 225 ? 135.410 213.880 181.373 1.00 120.85 ? 230 PHE M CE2   1 
ATOM   1677 C CZ    . PHE A 1 225 ? 134.767 215.032 180.983 1.00 120.85 ? 230 PHE M CZ    1 
ATOM   1678 N N     . GLY A 1 226 ? 134.315 210.031 175.386 1.00 122.00 ? 231 GLY M N     1 
ATOM   1679 C CA    . GLY A 1 226 ? 134.841 208.881 174.684 1.00 122.00 ? 231 GLY M CA    1 
ATOM   1680 C C     . GLY A 1 226 ? 134.486 208.811 173.216 1.00 122.00 ? 231 GLY M C     1 
ATOM   1681 O O     . GLY A 1 226 ? 134.564 207.741 172.609 1.00 122.00 ? 231 GLY M O     1 
ATOM   1682 N N     . ASN A 1 227 ? 134.083 209.931 172.634 1.00 123.01 ? 232 ASN M N     1 
ATOM   1683 C CA    . ASN A 1 227 ? 133.747 209.987 171.223 1.00 123.01 ? 232 ASN M CA    1 
ATOM   1684 C C     . ASN A 1 227 ? 134.548 211.083 170.543 1.00 123.01 ? 232 ASN M C     1 
ATOM   1685 O O     . ASN A 1 227 ? 134.784 212.150 171.114 1.00 123.01 ? 232 ASN M O     1 
ATOM   1686 C CB    . ASN A 1 227 ? 132.254 210.235 171.010 1.00 123.01 ? 232 ASN M CB    1 
ATOM   1687 C CG    . ASN A 1 227 ? 131.403 209.070 171.453 1.00 123.01 ? 232 ASN M CG    1 
ATOM   1688 O OD1   . ASN A 1 227 ? 131.916 208.008 171.797 1.00 123.01 ? 232 ASN M OD1   1 
ATOM   1689 N ND2   . ASN A 1 227 ? 130.092 209.263 171.452 1.00 123.01 ? 232 ASN M ND2   1 
ATOM   1690 N N     . ALA A 1 228 ? 134.955 210.813 169.308 1.00 122.69 ? 233 ALA M N     1 
ATOM   1691 C CA    . ALA A 1 228 ? 135.715 211.779 168.537 1.00 122.69 ? 233 ALA M CA    1 
ATOM   1692 C C     . ALA A 1 228 ? 135.405 211.582 167.063 1.00 122.69 ? 233 ALA M C     1 
ATOM   1693 O O     . ALA A 1 228 ? 134.969 210.512 166.635 1.00 122.69 ? 233 ALA M O     1 
ATOM   1694 C CB    . ALA A 1 228 ? 137.219 211.650 168.793 1.00 122.69 ? 233 ALA M CB    1 
ATOM   1695 N N     . LYS A 1 229 ? 135.644 212.632 166.291 1.00 123.40 ? 234 LYS M N     1 
ATOM   1696 C CA    . LYS A 1 229 ? 135.339 212.612 164.870 1.00 123.40 ? 234 LYS M CA    1 
ATOM   1697 C C     . LYS A 1 229 ? 136.416 211.842 164.117 1.00 123.40 ? 234 LYS M C     1 
ATOM   1698 O O     . LYS A 1 229 ? 137.584 212.241 164.113 1.00 123.40 ? 234 LYS M O     1 
ATOM   1699 C CB    . LYS A 1 229 ? 135.225 214.040 164.342 1.00 123.40 ? 234 LYS M CB    1 
ATOM   1700 C CG    . LYS A 1 229 ? 134.815 214.141 162.885 1.00 123.40 ? 234 LYS M CG    1 
ATOM   1701 C CD    . LYS A 1 229 ? 136.006 214.431 161.987 1.00 123.40 ? 234 LYS M CD    1 
ATOM   1702 C CE    . LYS A 1 229 ? 135.603 214.426 160.524 1.00 123.40 ? 234 LYS M CE    1 
ATOM   1703 N NZ    . LYS A 1 229 ? 136.771 214.590 159.622 1.00 123.40 ? 234 LYS M NZ    1 
ATOM   1704 N N     . THR A 1 230 ? 136.027 210.743 163.485 1.00 124.64 ? 235 THR M N     1 
ATOM   1705 C CA    . THR A 1 230 ? 136.833 210.096 162.461 1.00 124.64 ? 235 THR M CA    1 
ATOM   1706 C C     . THR A 1 230 ? 136.295 210.488 161.092 1.00 124.64 ? 235 THR M C     1 
ATOM   1707 O O     . THR A 1 230 ? 135.405 211.331 160.965 1.00 124.64 ? 235 THR M O     1 
ATOM   1708 C CB    . THR A 1 230 ? 136.846 208.574 162.626 1.00 124.64 ? 235 THR M CB    1 
ATOM   1709 O OG1   . THR A 1 230 ? 135.586 208.028 162.216 1.00 124.64 ? 235 THR M OG1   1 
ATOM   1710 C CG2   . THR A 1 230 ? 137.139 208.188 164.055 1.00 124.64 ? 235 THR M CG2   1 
ATOM   1711 N N     . VAL A 1 231 ? 136.851 209.872 160.050 1.00 125.26 ? 236 VAL M N     1 
ATOM   1712 C CA    . VAL A 1 231 ? 136.422 210.219 158.700 1.00 125.26 ? 236 VAL M CA    1 
ATOM   1713 C C     . VAL A 1 231 ? 135.107 209.533 158.361 1.00 125.26 ? 236 VAL M C     1 
ATOM   1714 O O     . VAL A 1 231 ? 134.202 210.147 157.785 1.00 125.26 ? 236 VAL M O     1 
ATOM   1715 C CB    . VAL A 1 231 ? 137.521 209.877 157.683 1.00 125.26 ? 236 VAL M CB    1 
ATOM   1716 C CG1   . VAL A 1 231 ? 137.219 210.540 156.348 1.00 125.26 ? 236 VAL M CG1   1 
ATOM   1717 C CG2   . VAL A 1 231 ? 138.875 210.317 158.211 1.00 125.26 ? 236 VAL M CG2   1 
ATOM   1718 N N     . ARG A 1 232 ? 134.974 208.256 158.714 1.00 128.50 ? 237 ARG M N     1 
ATOM   1719 C CA    . ARG A 1 232 ? 133.752 207.528 158.395 1.00 128.50 ? 237 ARG M CA    1 
ATOM   1720 C C     . ARG A 1 232 ? 132.584 207.952 159.276 1.00 128.50 ? 237 ARG M C     1 
ATOM   1721 O O     . ARG A 1 232 ? 131.430 207.659 158.947 1.00 128.50 ? 237 ARG M O     1 
ATOM   1722 C CB    . ARG A 1 232 ? 133.988 206.023 158.514 1.00 128.50 ? 237 ARG M CB    1 
ATOM   1723 C CG    . ARG A 1 232 ? 134.409 205.353 157.214 1.00 128.50 ? 237 ARG M CG    1 
ATOM   1724 C CD    . ARG A 1 232 ? 135.281 204.137 157.480 1.00 128.50 ? 237 ARG M CD    1 
ATOM   1725 N NE    . ARG A 1 232 ? 134.662 203.198 158.412 1.00 128.50 ? 237 ARG M NE    1 
ATOM   1726 C CZ    . ARG A 1 232 ? 134.129 202.035 158.058 1.00 128.50 ? 237 ARG M CZ    1 
ATOM   1727 N NH1   . ARG A 1 232 ? 134.141 201.659 156.789 1.00 128.50 ? 237 ARG M NH1   1 
ATOM   1728 N NH2   . ARG A 1 232 ? 133.588 201.244 158.971 1.00 128.50 ? 237 ARG M NH2   1 
ATOM   1729 N N     . ASN A 1 233 ? 132.850 208.616 160.398 1.00 127.20 ? 238 ASN M N     1 
ATOM   1730 C CA    . ASN A 1 233 ? 131.789 209.013 161.311 1.00 127.20 ? 238 ASN M CA    1 
ATOM   1731 C C     . ASN A 1 233 ? 132.202 210.245 162.098 1.00 127.20 ? 238 ASN M C     1 
ATOM   1732 O O     . ASN A 1 233 ? 133.372 210.399 162.453 1.00 127.20 ? 238 ASN M O     1 
ATOM   1733 C CB    . ASN A 1 233 ? 131.440 207.875 162.272 1.00 127.20 ? 238 ASN M CB    1 
ATOM   1734 C CG    . ASN A 1 233 ? 130.355 208.254 163.246 1.00 127.20 ? 238 ASN M CG    1 
ATOM   1735 O OD1   . ASN A 1 233 ? 129.649 209.243 163.057 1.00 127.20 ? 238 ASN M OD1   1 
ATOM   1736 N ND2   . ASN A 1 233 ? 130.213 207.467 164.298 1.00 127.20 ? 238 ASN M ND2   1 
ATOM   1737 N N     . ASP A 1 234 ? 131.232 211.114 162.382 1.00 126.52 ? 239 ASP M N     1 
ATOM   1738 C CA    . ASP A 1 234 ? 131.482 212.310 163.175 1.00 126.52 ? 239 ASP M CA    1 
ATOM   1739 C C     . ASP A 1 234 ? 131.182 212.128 164.653 1.00 126.52 ? 239 ASP M C     1 
ATOM   1740 O O     . ASP A 1 234 ? 131.418 213.054 165.432 1.00 126.52 ? 239 ASP M O     1 
ATOM   1741 C CB    . ASP A 1 234 ? 130.665 213.492 162.647 1.00 126.52 ? 239 ASP M CB    1 
ATOM   1742 C CG    . ASP A 1 234 ? 131.393 214.262 161.573 1.00 126.52 ? 239 ASP M CG    1 
ATOM   1743 O OD1   . ASP A 1 234 ? 132.185 213.643 160.832 1.00 126.52 ? 239 ASP M OD1   1 
ATOM   1744 O OD2   . ASP A 1 234 ? 131.191 215.489 161.479 1.00 126.52 ? 239 ASP M OD2   1 
ATOM   1745 N N     . ASN A 1 235 ? 130.652 210.982 165.058 1.00 126.03 ? 240 ASN M N     1 
ATOM   1746 C CA    . ASN A 1 235 ? 130.420 210.690 166.466 1.00 126.03 ? 240 ASN M CA    1 
ATOM   1747 C C     . ASN A 1 235 ? 130.873 209.278 166.785 1.00 126.03 ? 240 ASN M C     1 
ATOM   1748 O O     . ASN A 1 235 ? 130.172 208.496 167.428 1.00 126.03 ? 240 ASN M O     1 
ATOM   1749 C CB    . ASN A 1 235 ? 128.960 210.889 166.844 1.00 126.03 ? 240 ASN M CB    1 
ATOM   1750 C CG    . ASN A 1 235 ? 128.781 211.184 168.315 1.00 126.03 ? 240 ASN M CG    1 
ATOM   1751 O OD1   . ASN A 1 235 ? 129.433 210.577 169.162 1.00 126.03 ? 240 ASN M OD1   1 
ATOM   1752 N ND2   . ASN A 1 235 ? 127.903 212.127 168.628 1.00 126.03 ? 240 ASN M ND2   1 
ATOM   1753 N N     . SER A 1 236 ? 132.071 208.938 166.324 1.00 124.64 ? 241 SER M N     1 
ATOM   1754 C CA    . SER A 1 236 ? 132.611 207.601 166.518 1.00 124.64 ? 241 SER M CA    1 
ATOM   1755 C C     . SER A 1 236 ? 133.000 207.374 167.969 1.00 124.64 ? 241 SER M C     1 
ATOM   1756 O O     . SER A 1 236 ? 133.546 208.261 168.630 1.00 124.64 ? 241 SER M O     1 
ATOM   1757 C CB    . SER A 1 236 ? 133.828 207.402 165.626 1.00 124.64 ? 241 SER M CB    1 
ATOM   1758 O OG    . SER A 1 236 ? 134.644 208.557 165.684 1.00 124.64 ? 241 SER M OG    1 
ATOM   1759 N N     . SER A 1 237 ? 132.724 206.173 168.460 1.00 121.81 ? 242 SER M N     1 
ATOM   1760 C CA    . SER A 1 237 ? 133.129 205.781 169.799 1.00 121.81 ? 242 SER M CA    1 
ATOM   1761 C C     . SER A 1 237 ? 134.526 205.183 169.756 1.00 121.81 ? 242 SER M C     1 
ATOM   1762 O O     . SER A 1 237 ? 134.843 204.374 168.880 1.00 121.81 ? 242 SER M O     1 
ATOM   1763 C CB    . SER A 1 237 ? 132.146 204.771 170.390 1.00 121.81 ? 242 SER M CB    1 
ATOM   1764 O OG    . SER A 1 237 ? 132.123 203.579 169.626 1.00 121.81 ? 242 SER M OG    1 
ATOM   1765 N N     . ARG A 1 238 ? 135.359 205.590 170.706 1.00 118.71 ? 243 ARG M N     1 
ATOM   1766 C CA    . ARG A 1 238 ? 136.721 205.092 170.811 1.00 118.71 ? 243 ARG M CA    1 
ATOM   1767 C C     . ARG A 1 238 ? 136.889 204.056 171.905 1.00 118.71 ? 243 ARG M C     1 
ATOM   1768 O O     . ARG A 1 238 ? 137.633 203.094 171.726 1.00 118.71 ? 243 ARG M O     1 
ATOM   1769 C CB    . ARG A 1 238 ? 137.691 206.251 171.057 1.00 118.71 ? 243 ARG M CB    1 
ATOM   1770 C CG    . ARG A 1 238 ? 137.572 207.373 170.047 1.00 118.71 ? 243 ARG M CG    1 
ATOM   1771 C CD    . ARG A 1 238 ? 137.504 206.834 168.630 1.00 118.71 ? 243 ARG M CD    1 
ATOM   1772 N NE    . ARG A 1 238 ? 138.773 206.271 168.186 1.00 118.71 ? 243 ARG M NE    1 
ATOM   1773 C CZ    . ARG A 1 238 ? 138.920 205.556 167.077 1.00 118.71 ? 243 ARG M CZ    1 
ATOM   1774 N NH1   . ARG A 1 238 ? 137.872 205.308 166.307 1.00 118.71 ? 243 ARG M NH1   1 
ATOM   1775 N NH2   . ARG A 1 238 ? 140.110 205.081 166.741 1.00 118.71 ? 243 ARG M NH2   1 
ATOM   1776 N N     . PHE A 1 239 ? 136.212 204.228 173.032 1.00 120.89 ? 244 PHE M N     1 
ATOM   1777 C CA    . PHE A 1 239 ? 136.304 203.273 174.121 1.00 120.89 ? 244 PHE M CA    1 
ATOM   1778 C C     . PHE A 1 239 ? 135.299 202.145 173.943 1.00 120.89 ? 244 PHE M C     1 
ATOM   1779 O O     . PHE A 1 239 ? 134.266 202.300 173.289 1.00 120.89 ? 244 PHE M O     1 
ATOM   1780 C CB    . PHE A 1 239 ? 136.069 203.962 175.459 1.00 120.89 ? 244 PHE M CB    1 
ATOM   1781 C CG    . PHE A 1 239 ? 134.669 204.448 175.649 1.00 120.89 ? 244 PHE M CG    1 
ATOM   1782 C CD1   . PHE A 1 239 ? 134.227 205.584 175.002 1.00 120.89 ? 244 PHE M CD1   1 
ATOM   1783 C CD2   . PHE A 1 239 ? 133.797 203.776 176.481 1.00 120.89 ? 244 PHE M CD2   1 
ATOM   1784 C CE1   . PHE A 1 239 ? 132.945 206.038 175.174 1.00 120.89 ? 244 PHE M CE1   1 
ATOM   1785 C CE2   . PHE A 1 239 ? 132.515 204.226 176.661 1.00 120.89 ? 244 PHE M CE2   1 
ATOM   1786 C CZ    . PHE A 1 239 ? 132.086 205.359 176.006 1.00 120.89 ? 244 PHE M CZ    1 
ATOM   1787 N N     . GLY A 1 240 ? 135.616 201.001 174.536 1.00 123.37 ? 245 GLY M N     1 
ATOM   1788 C CA    . GLY A 1 240 ? 134.743 199.848 174.496 1.00 123.37 ? 245 GLY M CA    1 
ATOM   1789 C C     . GLY A 1 240 ? 133.675 199.823 175.569 1.00 123.37 ? 245 GLY M C     1 
ATOM   1790 O O     . GLY A 1 240 ? 133.821 199.110 176.565 1.00 123.37 ? 245 GLY M O     1 
ATOM   1791 N N     . LYS A 1 241 ? 132.610 200.604 175.396 1.00 128.29 ? 246 LYS M N     1 
ATOM   1792 C CA    . LYS A 1 241 ? 131.506 200.583 176.348 1.00 128.29 ? 246 LYS M CA    1 
ATOM   1793 C C     . LYS A 1 241 ? 130.906 199.184 176.450 1.00 128.29 ? 246 LYS M C     1 
ATOM   1794 O O     . LYS A 1 241 ? 130.870 198.424 175.479 1.00 128.29 ? 246 LYS M O     1 
ATOM   1795 C CB    . LYS A 1 241 ? 130.423 201.578 175.939 1.00 128.29 ? 246 LYS M CB    1 
ATOM   1796 C CG    . LYS A 1 241 ? 129.376 201.822 177.010 1.00 128.29 ? 246 LYS M CG    1 
ATOM   1797 C CD    . LYS A 1 241 ? 128.260 202.707 176.495 1.00 128.29 ? 246 LYS M CD    1 
ATOM   1798 C CE    . LYS A 1 241 ? 128.802 204.013 175.960 1.00 128.29 ? 246 LYS M CE    1 
ATOM   1799 N NZ    . LYS A 1 241 ? 127.727 204.845 175.358 1.00 128.29 ? 246 LYS M NZ    1 
ATOM   1800 N N     . PHE A 1 242 ? 130.433 198.847 177.647 1.00 131.11 ? 247 PHE M N     1 
ATOM   1801 C CA    . PHE A 1 242 ? 129.924 197.505 177.909 1.00 131.11 ? 247 PHE M CA    1 
ATOM   1802 C C     . PHE A 1 242 ? 129.074 197.569 179.168 1.00 131.11 ? 247 PHE M C     1 
ATOM   1803 O O     . PHE A 1 242 ? 129.610 197.770 180.260 1.00 131.11 ? 247 PHE M O     1 
ATOM   1804 C CB    . PHE A 1 242 ? 131.079 196.531 178.064 1.00 131.11 ? 247 PHE M CB    1 
ATOM   1805 C CG    . PHE A 1 242 ? 130.672 195.157 178.490 1.00 131.11 ? 247 PHE M CG    1 
ATOM   1806 C CD1   . PHE A 1 242 ? 130.181 194.253 177.574 1.00 131.11 ? 247 PHE M CD1   1 
ATOM   1807 C CD2   . PHE A 1 242 ? 130.814 194.758 179.801 1.00 131.11 ? 247 PHE M CD2   1 
ATOM   1808 C CE1   . PHE A 1 242 ? 129.820 192.984 177.960 1.00 131.11 ? 247 PHE M CE1   1 
ATOM   1809 C CE2   . PHE A 1 242 ? 130.460 193.492 180.186 1.00 131.11 ? 247 PHE M CE2   1 
ATOM   1810 C CZ    . PHE A 1 242 ? 129.960 192.604 179.269 1.00 131.11 ? 247 PHE M CZ    1 
ATOM   1811 N N     . ILE A 1 243 ? 127.766 197.377 179.021 1.00 134.65 ? 248 ILE M N     1 
ATOM   1812 C CA    . ILE A 1 243 ? 126.823 197.483 180.129 1.00 134.65 ? 248 ILE M CA    1 
ATOM   1813 C C     . ILE A 1 243 ? 126.465 196.085 180.610 1.00 134.65 ? 248 ILE M C     1 
ATOM   1814 O O     . ILE A 1 243 ? 125.962 195.262 179.836 1.00 134.65 ? 248 ILE M O     1 
ATOM   1815 C CB    . ILE A 1 243 ? 125.559 198.259 179.729 1.00 134.65 ? 248 ILE M CB    1 
ATOM   1816 C CG1   . ILE A 1 243 ? 125.873 199.732 179.462 1.00 134.65 ? 248 ILE M CG1   1 
ATOM   1817 C CG2   . ILE A 1 243 ? 124.525 198.144 180.812 1.00 134.65 ? 248 ILE M CG2   1 
ATOM   1818 C CD1   . ILE A 1 243 ? 126.163 200.059 178.020 1.00 134.65 ? 248 ILE M CD1   1 
ATOM   1819 N N     . ARG A 1 244 ? 126.714 195.821 181.890 1.00 137.24 ? 249 ARG M N     1 
ATOM   1820 C CA    . ARG A 1 244 ? 126.315 194.578 182.538 1.00 137.24 ? 249 ARG M CA    1 
ATOM   1821 C C     . ARG A 1 244 ? 124.959 194.787 183.197 1.00 137.24 ? 249 ARG M C     1 
ATOM   1822 O O     . ARG A 1 244 ? 124.819 195.653 184.066 1.00 137.24 ? 249 ARG M O     1 
ATOM   1823 C CB    . ARG A 1 244 ? 127.344 194.140 183.579 1.00 137.24 ? 249 ARG M CB    1 
ATOM   1824 C CG    . ARG A 1 244 ? 128.649 193.676 182.990 1.00 137.24 ? 249 ARG M CG    1 
ATOM   1825 C CD    . ARG A 1 244 ? 129.501 192.909 183.992 1.00 137.24 ? 249 ARG M CD    1 
ATOM   1826 N NE    . ARG A 1 244 ? 130.458 193.760 184.686 1.00 137.24 ? 249 ARG M NE    1 
ATOM   1827 C CZ    . ARG A 1 244 ? 130.368 194.089 185.968 1.00 137.24 ? 249 ARG M CZ    1 
ATOM   1828 N NH1   . ARG A 1 244 ? 129.364 193.630 186.696 1.00 137.24 ? 249 ARG M NH1   1 
ATOM   1829 N NH2   . ARG A 1 244 ? 131.283 194.871 186.523 1.00 137.24 ? 249 ARG M NH2   1 
ATOM   1830 N N     . ILE A 1 245 ? 123.970 194.001 182.782 1.00 141.87 ? 250 ILE M N     1 
ATOM   1831 C CA    . ILE A 1 245 ? 122.628 194.041 183.357 1.00 141.87 ? 250 ILE M CA    1 
ATOM   1832 C C     . ILE A 1 245 ? 122.505 192.837 184.281 1.00 141.87 ? 250 ILE M C     1 
ATOM   1833 O O     . ILE A 1 245 ? 122.294 191.711 183.825 1.00 141.87 ? 250 ILE M O     1 
ATOM   1834 C CB    . ILE A 1 245 ? 121.542 194.027 182.279 1.00 141.87 ? 250 ILE M CB    1 
ATOM   1835 C CG1   . ILE A 1 245 ? 121.619 195.279 181.406 1.00 141.87 ? 250 ILE M CG1   1 
ATOM   1836 C CG2   . ILE A 1 245 ? 120.178 193.935 182.924 1.00 141.87 ? 250 ILE M CG2   1 
ATOM   1837 C CD1   . ILE A 1 245 ? 121.689 196.554 182.190 1.00 141.87 ? 250 ILE M CD1   1 
ATOM   1838 N N     . HIS A 1 246 ? 122.626 193.071 185.583 1.00 144.00 ? 251 HIS M N     1 
ATOM   1839 C CA    . HIS A 1 246 ? 122.508 191.977 186.527 1.00 144.00 ? 251 HIS M CA    1 
ATOM   1840 C C     . HIS A 1 246 ? 121.050 191.594 186.730 1.00 144.00 ? 251 HIS M C     1 
ATOM   1841 O O     . HIS A 1 246 ? 120.128 192.246 186.236 1.00 144.00 ? 251 HIS M O     1 
ATOM   1842 C CB    . HIS A 1 246 ? 123.139 192.345 187.864 1.00 144.00 ? 251 HIS M CB    1 
ATOM   1843 C CG    . HIS A 1 246 ? 124.627 192.431 187.818 1.00 144.00 ? 251 HIS M CG    1 
ATOM   1844 N ND1   . HIS A 1 246 ? 125.442 191.337 188.014 1.00 144.00 ? 251 HIS M ND1   1 
ATOM   1845 C CD2   . HIS A 1 246 ? 125.451 193.479 187.591 1.00 144.00 ? 251 HIS M CD2   1 
ATOM   1846 C CE1   . HIS A 1 246 ? 126.705 191.709 187.913 1.00 144.00 ? 251 HIS M CE1   1 
ATOM   1847 N NE2   . HIS A 1 246 ? 126.738 193.004 187.658 1.00 144.00 ? 251 HIS M NE2   1 
ATOM   1848 N N     . PHE A 1 247 ? 120.850 190.507 187.467 1.00 146.97 ? 252 PHE M N     1 
ATOM   1849 C CA    . PHE A 1 247 ? 119.522 190.064 187.853 1.00 146.97 ? 252 PHE M CA    1 
ATOM   1850 C C     . PHE A 1 247 ? 119.605 189.443 189.236 1.00 146.97 ? 252 PHE M C     1 
ATOM   1851 O O     . PHE A 1 247 ? 120.654 189.454 189.881 1.00 146.97 ? 252 PHE M O     1 
ATOM   1852 C CB    . PHE A 1 247 ? 118.930 189.075 186.846 1.00 146.97 ? 252 PHE M CB    1 
ATOM   1853 C CG    . PHE A 1 247 ? 118.556 189.701 185.541 1.00 146.97 ? 252 PHE M CG    1 
ATOM   1854 C CD1   . PHE A 1 247 ? 119.224 189.366 184.380 1.00 146.97 ? 252 PHE M CD1   1 
ATOM   1855 C CD2   . PHE A 1 247 ? 117.552 190.648 185.478 1.00 146.97 ? 252 PHE M CD2   1 
ATOM   1856 C CE1   . PHE A 1 247 ? 118.878 189.951 183.178 1.00 146.97 ? 252 PHE M CE1   1 
ATOM   1857 C CE2   . PHE A 1 247 ? 117.208 191.236 184.280 1.00 146.97 ? 252 PHE M CE2   1 
ATOM   1858 C CZ    . PHE A 1 247 ? 117.871 190.887 183.131 1.00 146.97 ? 252 PHE M CZ    1 
ATOM   1859 N N     . GLY A 1 248 ? 118.472 188.930 189.706 1.00 149.69 ? 253 GLY M N     1 
ATOM   1860 C CA    . GLY A 1 248 ? 118.401 188.267 190.987 1.00 149.69 ? 253 GLY M CA    1 
ATOM   1861 C C     . GLY A 1 248 ? 118.355 186.760 190.844 1.00 149.69 ? 253 GLY M C     1 
ATOM   1862 O O     . GLY A 1 248 ? 118.667 186.188 189.798 1.00 149.69 ? 253 GLY M O     1 
ATOM   1863 N N     . ALA A 1 249 ? 117.966 186.107 191.941 1.00 150.84 ? 254 ALA M N     1 
ATOM   1864 C CA    . ALA A 1 249 ? 117.725 184.670 191.896 1.00 150.84 ? 254 ALA M CA    1 
ATOM   1865 C C     . ALA A 1 249 ? 116.437 184.360 191.145 1.00 150.84 ? 254 ALA M C     1 
ATOM   1866 O O     . ALA A 1 249 ? 116.366 183.387 190.386 1.00 150.84 ? 254 ALA M O     1 
ATOM   1867 C CB    . ALA A 1 249 ? 117.674 184.107 193.315 1.00 150.84 ? 254 ALA M CB    1 
ATOM   1868 N N     . THR A 1 250 ? 115.417 185.185 191.337 1.00 152.92 ? 255 THR M N     1 
ATOM   1869 C CA    . THR A 1 250 ? 114.140 185.063 190.654 1.00 152.92 ? 255 THR M CA    1 
ATOM   1870 C C     . THR A 1 250 ? 114.163 185.640 189.248 1.00 152.92 ? 255 THR M C     1 
ATOM   1871 O O     . THR A 1 250 ? 113.093 185.882 188.673 1.00 152.92 ? 255 THR M O     1 
ATOM   1872 C CB    . THR A 1 250 ? 113.044 185.739 191.484 1.00 152.92 ? 255 THR M CB    1 
ATOM   1873 O OG1   . THR A 1 250 ? 111.792 185.667 190.791 1.00 152.92 ? 255 THR M OG1   1 
ATOM   1874 C CG2   . THR A 1 250 ? 113.402 187.184 191.760 1.00 152.92 ? 255 THR M CG2   1 
ATOM   1875 N N     . GLY A 1 251 ? 115.348 185.869 188.687 1.00 151.18 ? 256 GLY M N     1 
ATOM   1876 C CA    . GLY A 1 251 ? 115.445 186.397 187.339 1.00 151.18 ? 256 GLY M CA    1 
ATOM   1877 C C     . GLY A 1 251 ? 114.786 187.743 187.152 1.00 151.18 ? 256 GLY M C     1 
ATOM   1878 O O     . GLY A 1 251 ? 114.417 188.093 186.027 1.00 151.18 ? 256 GLY M O     1 
ATOM   1879 N N     . LYS A 1 252 ? 114.630 188.511 188.223 1.00 150.00 ? 257 LYS M N     1 
ATOM   1880 C CA    . LYS A 1 252 ? 113.996 189.817 188.150 1.00 150.00 ? 257 LYS M CA    1 
ATOM   1881 C C     . LYS A 1 252 ? 115.048 190.916 188.205 1.00 150.00 ? 257 LYS M C     1 
ATOM   1882 O O     . LYS A 1 252 ? 116.144 190.727 188.739 1.00 150.00 ? 257 LYS M O     1 
ATOM   1883 C CB    . LYS A 1 252 ? 112.974 189.995 189.274 1.00 150.00 ? 257 LYS M CB    1 
ATOM   1884 C CG    . LYS A 1 252 ? 111.812 189.010 189.188 1.00 150.00 ? 257 LYS M CG    1 
ATOM   1885 C CD    . LYS A 1 252 ? 110.643 189.428 190.062 1.00 150.00 ? 257 LYS M CD    1 
ATOM   1886 C CE    . LYS A 1 252 ? 110.031 190.733 189.583 1.00 150.00 ? 257 LYS M CE    1 
ATOM   1887 N NZ    . LYS A 1 252 ? 109.603 190.674 188.160 1.00 150.00 ? 257 LYS M NZ    1 
ATOM   1888 N N     . LEU A 1 253 ? 114.701 192.067 187.630 1.00 148.39 ? 258 LEU M N     1 
ATOM   1889 C CA    . LEU A 1 253 ? 115.651 193.158 187.459 1.00 148.39 ? 258 LEU M CA    1 
ATOM   1890 C C     . LEU A 1 253 ? 116.222 193.589 188.801 1.00 148.39 ? 258 LEU M C     1 
ATOM   1891 O O     . LEU A 1 253 ? 115.481 193.994 189.700 1.00 148.39 ? 258 LEU M O     1 
ATOM   1892 C CB    . LEU A 1 253 ? 114.966 194.336 186.773 1.00 148.39 ? 258 LEU M CB    1 
ATOM   1893 C CG    . LEU A 1 253 ? 115.878 195.314 186.040 1.00 148.39 ? 258 LEU M CG    1 
ATOM   1894 C CD1   . LEU A 1 253 ? 116.459 194.643 184.814 1.00 148.39 ? 258 LEU M CD1   1 
ATOM   1895 C CD2   . LEU A 1 253 ? 115.127 196.581 185.663 1.00 148.39 ? 258 LEU M CD2   1 
ATOM   1896 N N     . ALA A 1 254 ? 117.545 193.512 188.932 1.00 146.42 ? 259 ALA M N     1 
ATOM   1897 C CA    . ALA A 1 254 ? 118.216 193.829 190.183 1.00 146.42 ? 259 ALA M CA    1 
ATOM   1898 C C     . ALA A 1 254 ? 119.024 195.118 190.101 1.00 146.42 ? 259 ALA M C     1 
ATOM   1899 O O     . ALA A 1 254 ? 118.788 196.043 190.884 1.00 146.42 ? 259 ALA M O     1 
ATOM   1900 C CB    . ALA A 1 254 ? 119.116 192.659 190.593 1.00 146.42 ? 259 ALA M CB    1 
ATOM   1901 N N     . SER A 1 255 ? 119.968 195.211 189.166 1.00 143.57 ? 260 SER M N     1 
ATOM   1902 C CA    . SER A 1 255 ? 120.814 196.392 189.027 1.00 143.57 ? 260 SER M CA    1 
ATOM   1903 C C     . SER A 1 255 ? 121.588 196.280 187.721 1.00 143.57 ? 260 SER M C     1 
ATOM   1904 O O     . SER A 1 255 ? 121.567 195.245 187.049 1.00 143.57 ? 260 SER M O     1 
ATOM   1905 C CB    . SER A 1 255 ? 121.773 196.551 190.212 1.00 143.57 ? 260 SER M CB    1 
ATOM   1906 O OG    . SER A 1 255 ? 121.064 196.739 191.425 1.00 143.57 ? 260 SER M OG    1 
ATOM   1907 N N     . ALA A 1 256 ? 122.284 197.360 187.376 1.00 138.59 ? 261 ALA M N     1 
ATOM   1908 C CA    . ALA A 1 256 ? 123.052 197.438 186.143 1.00 138.59 ? 261 ALA M CA    1 
ATOM   1909 C C     . ALA A 1 256 ? 124.475 197.886 186.444 1.00 138.59 ? 261 ALA M C     1 
ATOM   1910 O O     . ALA A 1 256 ? 124.697 198.746 187.300 1.00 138.59 ? 261 ALA M O     1 
ATOM   1911 C CB    . ALA A 1 256 ? 122.398 198.400 185.147 1.00 138.59 ? 261 ALA M CB    1 
ATOM   1912 N N     . ASP A 1 257 ? 125.437 197.292 185.740 1.00 136.45 ? 262 ASP M N     1 
ATOM   1913 C CA    . ASP A 1 257 ? 126.846 197.623 185.889 1.00 136.45 ? 262 ASP M CA    1 
ATOM   1914 C C     . ASP A 1 257 ? 127.418 197.996 184.532 1.00 136.45 ? 262 ASP M C     1 
ATOM   1915 O O     . ASP A 1 257 ? 126.879 197.613 183.490 1.00 136.45 ? 262 ASP M O     1 
ATOM   1916 C CB    . ASP A 1 257 ? 127.652 196.462 186.475 1.00 136.45 ? 262 ASP M CB    1 
ATOM   1917 C CG    . ASP A 1 257 ? 127.250 196.128 187.895 1.00 136.45 ? 262 ASP M CG    1 
ATOM   1918 O OD1   . ASP A 1 257 ? 126.402 196.847 188.463 1.00 136.45 ? 262 ASP M OD1   1 
ATOM   1919 O OD2   . ASP A 1 257 ? 127.785 195.140 188.445 1.00 136.45 ? 262 ASP M OD2   1 
ATOM   1920 N N     . ILE A 1 258 ? 128.516 198.746 184.552 1.00 130.52 ? 263 ILE M N     1 
ATOM   1921 C CA    . ILE A 1 258 ? 129.127 199.262 183.333 1.00 130.52 ? 263 ILE M CA    1 
ATOM   1922 C C     . ILE A 1 258 ? 130.640 199.249 183.498 1.00 130.52 ? 263 ILE M C     1 
ATOM   1923 O O     . ILE A 1 258 ? 131.162 199.532 184.581 1.00 130.52 ? 263 ILE M O     1 
ATOM   1924 C CB    . ILE A 1 258 ? 128.607 200.678 183.004 1.00 130.52 ? 263 ILE M CB    1 
ATOM   1925 C CG1   . ILE A 1 258 ? 129.172 201.169 181.676 1.00 130.52 ? 263 ILE M CG1   1 
ATOM   1926 C CG2   . ILE A 1 258 ? 128.951 201.653 184.116 1.00 130.52 ? 263 ILE M CG2   1 
ATOM   1927 C CD1   . ILE A 1 258 ? 128.681 202.543 181.294 1.00 130.52 ? 263 ILE M CD1   1 
ATOM   1928 N N     . GLU A 1 259 ? 131.345 198.898 182.425 1.00 127.29 ? 264 GLU M N     1 
ATOM   1929 C CA    . GLU A 1 259 ? 132.798 198.897 182.415 1.00 127.29 ? 264 GLU M CA    1 
ATOM   1930 C C     . GLU A 1 259 ? 133.289 199.482 181.102 1.00 127.29 ? 264 GLU M C     1 
ATOM   1931 O O     . GLU A 1 259 ? 132.641 199.344 180.062 1.00 127.29 ? 264 GLU M O     1 
ATOM   1932 C CB    . GLU A 1 259 ? 133.370 197.487 182.593 1.00 127.29 ? 264 GLU M CB    1 
ATOM   1933 C CG    . GLU A 1 259 ? 133.178 196.901 183.975 1.00 127.29 ? 264 GLU M CG    1 
ATOM   1934 C CD    . GLU A 1 259 ? 133.623 195.457 184.056 1.00 127.29 ? 264 GLU M CD    1 
ATOM   1935 O OE1   . GLU A 1 259 ? 133.837 194.840 182.993 1.00 127.29 ? 264 GLU M OE1   1 
ATOM   1936 O OE2   . GLU A 1 259 ? 133.754 194.934 185.182 1.00 127.29 ? 264 GLU M OE2   1 
ATOM   1937 N N     . THR A 1 260 ? 134.447 200.128 181.156 1.00 119.89 ? 265 THR M N     1 
ATOM   1938 C CA    . THR A 1 260 ? 135.075 200.702 179.979 1.00 119.89 ? 265 THR M CA    1 
ATOM   1939 C C     . THR A 1 260 ? 136.361 199.949 179.675 1.00 119.89 ? 265 THR M C     1 
ATOM   1940 O O     . THR A 1 260 ? 137.106 199.577 180.586 1.00 119.89 ? 265 THR M O     1 
ATOM   1941 C CB    . THR A 1 260 ? 135.361 202.189 180.171 1.00 119.89 ? 265 THR M CB    1 
ATOM   1942 O OG1   . THR A 1 260 ? 134.125 202.890 180.340 1.00 119.89 ? 265 THR M OG1   1 
ATOM   1943 C CG2   . THR A 1 260 ? 136.077 202.747 178.964 1.00 119.89 ? 265 THR M CG2   1 
ATOM   1944 N N     . TYR A 1 261 ? 136.603 199.712 178.390 1.00 117.08 ? 266 TYR M N     1 
ATOM   1945 C CA    . TYR A 1 261 ? 137.750 198.950 177.933 1.00 117.08 ? 266 TYR M CA    1 
ATOM   1946 C C     . TYR A 1 261 ? 138.400 199.667 176.764 1.00 117.08 ? 266 TYR M C     1 
ATOM   1947 O O     . TYR A 1 261 ? 137.731 200.353 175.990 1.00 117.08 ? 266 TYR M O     1 
ATOM   1948 C CB    . TYR A 1 261 ? 137.354 197.544 177.481 1.00 117.08 ? 266 TYR M CB    1 
ATOM   1949 C CG    . TYR A 1 261 ? 136.922 196.624 178.586 1.00 117.08 ? 266 TYR M CG    1 
ATOM   1950 C CD1   . TYR A 1 261 ? 137.743 195.596 179.014 1.00 117.08 ? 266 TYR M CD1   1 
ATOM   1951 C CD2   . TYR A 1 261 ? 135.692 196.773 179.194 1.00 117.08 ? 266 TYR M CD2   1 
ATOM   1952 C CE1   . TYR A 1 261 ? 137.352 194.747 180.019 1.00 117.08 ? 266 TYR M CE1   1 
ATOM   1953 C CE2   . TYR A 1 261 ? 135.295 195.931 180.197 1.00 117.08 ? 266 TYR M CE2   1 
ATOM   1954 C CZ    . TYR A 1 261 ? 136.126 194.920 180.607 1.00 117.08 ? 266 TYR M CZ    1 
ATOM   1955 O OH    . TYR A 1 261 ? 135.729 194.075 181.612 1.00 117.08 ? 266 TYR M OH    1 
ATOM   1956 N N     . LEU A 1 262 ? 139.715 199.502 176.652 1.00 111.05 ? 267 LEU M N     1 
ATOM   1957 C CA    . LEU A 1 262 ? 140.445 199.793 175.422 1.00 111.05 ? 267 LEU M CA    1 
ATOM   1958 C C     . LEU A 1 262 ? 140.281 201.237 174.968 1.00 111.05 ? 267 LEU M C     1 
ATOM   1959 O O     . LEU A 1 262 ? 140.350 201.528 173.774 1.00 111.05 ? 267 LEU M O     1 
ATOM   1960 C CB    . LEU A 1 262 ? 140.011 198.843 174.307 1.00 111.05 ? 267 LEU M CB    1 
ATOM   1961 C CG    . LEU A 1 262 ? 139.955 197.373 174.707 1.00 111.05 ? 267 LEU M CG    1 
ATOM   1962 C CD1   . LEU A 1 262 ? 139.672 196.509 173.505 1.00 111.05 ? 267 LEU M CD1   1 
ATOM   1963 C CD2   . LEU A 1 262 ? 141.260 196.957 175.337 1.00 111.05 ? 267 LEU M CD2   1 
ATOM   1964 N N     . LEU A 1 263 ? 140.065 202.156 175.899 1.00 110.72 ? 268 LEU M N     1 
ATOM   1965 C CA    . LEU A 1 263 ? 139.973 203.563 175.534 1.00 110.72 ? 268 LEU M CA    1 
ATOM   1966 C C     . LEU A 1 263 ? 141.303 204.024 174.952 1.00 110.72 ? 268 LEU M C     1 
ATOM   1967 O O     . LEU A 1 263 ? 142.341 203.921 175.608 1.00 110.72 ? 268 LEU M O     1 
ATOM   1968 C CB    . LEU A 1 263 ? 139.594 204.400 176.750 1.00 110.72 ? 268 LEU M CB    1 
ATOM   1969 C CG    . LEU A 1 263 ? 139.728 205.907 176.560 1.00 110.72 ? 268 LEU M CG    1 
ATOM   1970 C CD1   . LEU A 1 263 ? 138.803 206.385 175.473 1.00 110.72 ? 268 LEU M CD1   1 
ATOM   1971 C CD2   . LEU A 1 263 ? 139.440 206.632 177.852 1.00 110.72 ? 268 LEU M CD2   1 
ATOM   1972 N N     . GLU A 1 264 ? 141.277 204.526 173.724 1.00 110.06 ? 269 GLU M N     1 
ATOM   1973 C CA    . GLU A 1 264 ? 142.506 204.911 173.046 1.00 110.06 ? 269 GLU M CA    1 
ATOM   1974 C C     . GLU A 1 264 ? 143.059 206.202 173.633 1.00 110.06 ? 269 GLU M C     1 
ATOM   1975 O O     . GLU A 1 264 ? 142.360 207.215 173.697 1.00 110.06 ? 269 GLU M O     1 
ATOM   1976 C CB    . GLU A 1 264 ? 142.267 205.074 171.547 1.00 110.06 ? 269 GLU M CB    1 
ATOM   1977 C CG    . GLU A 1 264 ? 143.451 205.666 170.787 1.00 110.06 ? 269 GLU M CG    1 
ATOM   1978 C CD    . GLU A 1 264 ? 144.778 204.979 171.101 1.00 110.06 ? 269 GLU M CD    1 
ATOM   1979 O OE1   . GLU A 1 264 ? 145.479 205.429 172.033 1.00 110.06 ? 269 GLU M OE1   1 
ATOM   1980 O OE2   . GLU A 1 264 ? 145.123 203.992 170.416 1.00 110.06 ? 269 GLU M OE2   1 
ATOM   1981 N N     . LYS A 1 265 ? 144.325 206.164 174.048 1.00 107.92 ? 270 LYS M N     1 
ATOM   1982 C CA    . LYS A 1 265 ? 144.976 207.329 174.629 1.00 107.92 ? 270 LYS M CA    1 
ATOM   1983 C C     . LYS A 1 265 ? 145.688 208.190 173.597 1.00 107.92 ? 270 LYS M C     1 
ATOM   1984 O O     . LYS A 1 265 ? 145.850 209.394 173.818 1.00 107.92 ? 270 LYS M O     1 
ATOM   1985 C CB    . LYS A 1 265 ? 145.988 206.899 175.694 1.00 107.92 ? 270 LYS M CB    1 
ATOM   1986 C CG    . LYS A 1 265 ? 145.413 206.670 177.077 1.00 107.92 ? 270 LYS M CG    1 
ATOM   1987 C CD    . LYS A 1 265 ? 144.636 205.377 177.124 1.00 107.92 ? 270 LYS M CD    1 
ATOM   1988 C CE    . LYS A 1 265 ? 145.550 204.184 176.925 1.00 107.92 ? 270 LYS M CE    1 
ATOM   1989 N NZ    . LYS A 1 265 ? 144.801 202.901 176.973 1.00 107.92 ? 270 LYS M NZ    1 
ATOM   1990 N N     . SER A 1 266 ? 146.118 207.606 172.477 1.00 109.29 ? 271 SER M N     1 
ATOM   1991 C CA    . SER A 1 266 ? 146.861 208.366 171.480 1.00 109.29 ? 271 SER M CA    1 
ATOM   1992 C C     . SER A 1 266 ? 146.078 209.555 170.945 1.00 109.29 ? 271 SER M C     1 
ATOM   1993 O O     . SER A 1 266 ? 146.686 210.510 170.448 1.00 109.29 ? 271 SER M O     1 
ATOM   1994 C CB    . SER A 1 266 ? 147.257 207.460 170.318 1.00 109.29 ? 271 SER M CB    1 
ATOM   1995 O OG    . SER A 1 266 ? 147.749 206.223 170.789 1.00 109.29 ? 271 SER M OG    1 
ATOM   1996 N N     . ARG A 1 267 ? 144.747 209.509 171.008 1.00 113.78 ? 272 ARG M N     1 
ATOM   1997 C CA    . ARG A 1 267 ? 143.951 210.615 170.493 1.00 113.78 ? 272 ARG M CA    1 
ATOM   1998 C C     . ARG A 1 267 ? 144.180 211.885 171.293 1.00 113.78 ? 272 ARG M C     1 
ATOM   1999 O O     . ARG A 1 267 ? 144.149 212.983 170.731 1.00 113.78 ? 272 ARG M O     1 
ATOM   2000 C CB    . ARG A 1 267 ? 142.468 210.251 170.514 1.00 113.78 ? 272 ARG M CB    1 
ATOM   2001 C CG    . ARG A 1 267 ? 142.156 208.840 170.063 1.00 113.78 ? 272 ARG M CG    1 
ATOM   2002 C CD    . ARG A 1 267 ? 142.098 208.728 168.551 1.00 113.78 ? 272 ARG M CD    1 
ATOM   2003 N NE    . ARG A 1 267 ? 141.043 209.559 167.980 1.00 113.78 ? 272 ARG M NE    1 
ATOM   2004 C CZ    . ARG A 1 267 ? 140.486 209.347 166.794 1.00 113.78 ? 272 ARG M CZ    1 
ATOM   2005 N NH1   . ARG A 1 267 ? 140.872 208.324 166.049 1.00 113.78 ? 272 ARG M NH1   1 
ATOM   2006 N NH2   . ARG A 1 267 ? 139.537 210.156 166.354 1.00 113.78 ? 272 ARG M NH2   1 
ATOM   2007 N N     . VAL A 1 268 ? 144.422 211.758 172.598 1.00 110.34 ? 273 VAL M N     1 
ATOM   2008 C CA    . VAL A 1 268 ? 144.550 212.932 173.444 1.00 110.34 ? 273 VAL M CA    1 
ATOM   2009 C C     . VAL A 1 268 ? 145.752 213.777 173.052 1.00 110.34 ? 273 VAL M C     1 
ATOM   2010 O O     . VAL A 1 268 ? 145.830 214.951 173.425 1.00 110.34 ? 273 VAL M O     1 
ATOM   2011 C CB    . VAL A 1 268 ? 144.634 212.503 174.919 1.00 110.34 ? 273 VAL M CB    1 
ATOM   2012 C CG1   . VAL A 1 268 ? 144.351 213.670 175.836 1.00 110.34 ? 273 VAL M CG1   1 
ATOM   2013 C CG2   . VAL A 1 268 ? 143.676 211.365 175.191 1.00 110.34 ? 273 VAL M CG2   1 
ATOM   2014 N N     . ILE A 1 269 ? 146.689 213.218 172.295 1.00 109.90 ? 274 ILE M N     1 
ATOM   2015 C CA    . ILE A 1 269 ? 147.921 213.907 171.927 1.00 109.90 ? 274 ILE M CA    1 
ATOM   2016 C C     . ILE A 1 269 ? 148.037 214.071 170.417 1.00 109.90 ? 274 ILE M C     1 
ATOM   2017 O O     . ILE A 1 269 ? 148.142 215.190 169.915 1.00 109.90 ? 274 ILE M O     1 
ATOM   2018 C CB    . ILE A 1 269 ? 149.155 213.185 172.508 1.00 109.90 ? 274 ILE M CB    1 
ATOM   2019 C CG1   . ILE A 1 269 ? 149.105 213.209 174.029 1.00 109.90 ? 274 ILE M CG1   1 
ATOM   2020 C CG2   . ILE A 1 269 ? 150.427 213.849 172.027 1.00 109.90 ? 274 ILE M CG2   1 
ATOM   2021 C CD1   . ILE A 1 269 ? 149.206 214.592 174.598 1.00 109.90 ? 274 ILE M CD1   1 
ATOM   2022 N N     . PHE A 1 270 ? 148.024 212.968 169.675 1.00 110.90 ? 275 PHE M N     1 
ATOM   2023 C CA    . PHE A 1 270 ? 148.219 212.997 168.232 1.00 110.90 ? 275 PHE M CA    1 
ATOM   2024 C C     . PHE A 1 270 ? 146.895 212.764 167.526 1.00 110.90 ? 275 PHE M C     1 
ATOM   2025 O O     . PHE A 1 270 ? 146.159 211.834 167.871 1.00 110.90 ? 275 PHE M O     1 
ATOM   2026 C CB    . PHE A 1 270 ? 149.227 211.941 167.779 1.00 110.90 ? 275 PHE M CB    1 
ATOM   2027 C CG    . PHE A 1 270 ? 150.553 212.030 168.466 1.00 110.90 ? 275 PHE M CG    1 
ATOM   2028 C CD1   . PHE A 1 270 ? 151.390 213.104 168.244 1.00 110.90 ? 275 PHE M CD1   1 
ATOM   2029 C CD2   . PHE A 1 270 ? 150.969 211.025 169.325 1.00 110.90 ? 275 PHE M CD2   1 
ATOM   2030 C CE1   . PHE A 1 270 ? 152.614 213.181 168.873 1.00 110.90 ? 275 PHE M CE1   1 
ATOM   2031 C CE2   . PHE A 1 270 ? 152.187 211.098 169.957 1.00 110.90 ? 275 PHE M CE2   1 
ATOM   2032 C CZ    . PHE A 1 270 ? 153.012 212.178 169.731 1.00 110.90 ? 275 PHE M CZ    1 
ATOM   2033 N N     . GLN A 1 271 ? 146.604 213.604 166.534 1.00 116.57 ? 276 GLN M N     1 
ATOM   2034 C CA    . GLN A 1 271 ? 145.436 213.457 165.678 1.00 116.57 ? 276 GLN M CA    1 
ATOM   2035 C C     . GLN A 1 271 ? 145.886 213.443 164.228 1.00 116.57 ? 276 GLN M C     1 
ATOM   2036 O O     . GLN A 1 271 ? 146.860 214.102 163.857 1.00 116.57 ? 276 GLN M O     1 
ATOM   2037 C CB    . GLN A 1 271 ? 144.420 214.582 165.881 1.00 116.57 ? 276 GLN M CB    1 
ATOM   2038 C CG    . GLN A 1 271 ? 143.820 214.643 167.262 1.00 116.57 ? 276 GLN M CG    1 
ATOM   2039 C CD    . GLN A 1 271 ? 144.714 215.366 168.229 1.00 116.57 ? 276 GLN M CD    1 
ATOM   2040 O OE1   . GLN A 1 271 ? 145.691 215.992 167.830 1.00 116.57 ? 276 GLN M OE1   1 
ATOM   2041 N NE2   . GLN A 1 271 ? 144.393 215.283 169.508 1.00 116.57 ? 276 GLN M NE2   1 
ATOM   2042 N N     . LEU A 1 272 ? 145.161 212.688 163.409 1.00 119.08 ? 277 LEU M N     1 
ATOM   2043 C CA    . LEU A 1 272 ? 145.511 212.537 162.006 1.00 119.08 ? 277 LEU M CA    1 
ATOM   2044 C C     . LEU A 1 272 ? 145.253 213.835 161.245 1.00 119.08 ? 277 LEU M C     1 
ATOM   2045 O O     . LEU A 1 272 ? 144.880 214.866 161.810 1.00 119.08 ? 277 LEU M O     1 
ATOM   2046 C CB    . LEU A 1 272 ? 144.731 211.383 161.382 1.00 119.08 ? 277 LEU M CB    1 
ATOM   2047 C CG    . LEU A 1 272 ? 145.343 209.988 161.504 1.00 119.08 ? 277 LEU M CG    1 
ATOM   2048 C CD1   . LEU A 1 272 ? 146.696 209.957 160.818 1.00 119.08 ? 277 LEU M CD1   1 
ATOM   2049 C CD2   . LEU A 1 272 ? 145.455 209.535 162.946 1.00 119.08 ? 277 LEU M CD2   1 
ATOM   2050 N N     . LYS A 1 273 ? 145.474 213.778 159.931 1.00 122.39 ? 278 LYS M N     1 
ATOM   2051 C CA    . LYS A 1 273 ? 145.258 214.950 159.092 1.00 122.39 ? 278 LYS M CA    1 
ATOM   2052 C C     . LYS A 1 273 ? 143.778 215.259 158.919 1.00 122.39 ? 278 LYS M C     1 
ATOM   2053 O O     . LYS A 1 273 ? 143.412 216.424 158.730 1.00 122.39 ? 278 LYS M O     1 
ATOM   2054 C CB    . LYS A 1 273 ? 145.914 214.749 157.725 1.00 122.39 ? 278 LYS M CB    1 
ATOM   2055 C CG    . LYS A 1 273 ? 147.339 215.281 157.613 1.00 122.39 ? 278 LYS M CG    1 
ATOM   2056 C CD    . LYS A 1 273 ? 148.281 214.623 158.609 1.00 122.39 ? 278 LYS M CD    1 
ATOM   2057 C CE    . LYS A 1 273 ? 148.390 213.123 158.376 1.00 122.39 ? 278 LYS M CE    1 
ATOM   2058 N NZ    . LYS A 1 273 ? 149.221 212.461 159.417 1.00 122.39 ? 278 LYS M NZ    1 
ATOM   2059 N N     . ALA A 1 274 ? 142.916 214.246 158.991 1.00 123.44 ? 279 ALA M N     1 
ATOM   2060 C CA    . ALA A 1 274 ? 141.510 214.396 158.642 1.00 123.44 ? 279 ALA M CA    1 
ATOM   2061 C C     . ALA A 1 274 ? 140.560 214.226 159.822 1.00 123.44 ? 279 ALA M C     1 
ATOM   2062 O O     . ALA A 1 274 ? 139.346 214.162 159.612 1.00 123.44 ? 279 ALA M O     1 
ATOM   2063 C CB    . ALA A 1 274 ? 141.139 213.401 157.542 1.00 123.44 ? 279 ALA M CB    1 
ATOM   2064 N N     . GLU A 1 275 ? 141.062 214.152 161.050 1.00 123.56 ? 280 GLU M N     1 
ATOM   2065 C CA    . GLU A 1 275 ? 140.209 213.841 162.187 1.00 123.56 ? 280 GLU M CA    1 
ATOM   2066 C C     . GLU A 1 275 ? 140.517 214.770 163.350 1.00 123.56 ? 280 GLU M C     1 
ATOM   2067 O O     . GLU A 1 275 ? 141.540 215.453 163.371 1.00 123.56 ? 280 GLU M O     1 
ATOM   2068 C CB    . GLU A 1 275 ? 140.367 212.379 162.610 1.00 123.56 ? 280 GLU M CB    1 
ATOM   2069 C CG    . GLU A 1 275 ? 139.959 211.405 161.515 1.00 123.56 ? 280 GLU M CG    1 
ATOM   2070 C CD    . GLU A 1 275 ? 140.183 209.957 161.892 1.00 123.56 ? 280 GLU M CD    1 
ATOM   2071 O OE1   . GLU A 1 275 ? 140.271 209.659 163.100 1.00 123.56 ? 280 GLU M OE1   1 
ATOM   2072 O OE2   . GLU A 1 275 ? 140.271 209.117 160.974 1.00 123.56 ? 280 GLU M OE2   1 
ATOM   2073 N N     . ARG A 1 276 ? 139.604 214.797 164.313 1.00 124.50 ? 281 ARG M N     1 
ATOM   2074 C CA    . ARG A 1 276 ? 139.700 215.676 165.466 1.00 124.50 ? 281 ARG M CA    1 
ATOM   2075 C C     . ARG A 1 276 ? 140.047 214.886 166.720 1.00 124.50 ? 281 ARG M C     1 
ATOM   2076 O O     . ARG A 1 276 ? 140.060 213.654 166.735 1.00 124.50 ? 281 ARG M O     1 
ATOM   2077 C CB    . ARG A 1 276 ? 138.387 216.427 165.710 1.00 124.50 ? 281 ARG M CB    1 
ATOM   2078 C CG    . ARG A 1 276 ? 137.625 216.872 164.488 1.00 124.50 ? 281 ARG M CG    1 
ATOM   2079 C CD    . ARG A 1 276 ? 136.393 217.640 164.926 1.00 124.50 ? 281 ARG M CD    1 
ATOM   2080 N NE    . ARG A 1 276 ? 136.739 218.937 165.498 1.00 124.50 ? 281 ARG M NE    1 
ATOM   2081 C CZ    . ARG A 1 276 ? 135.858 219.773 166.036 1.00 124.50 ? 281 ARG M CZ    1 
ATOM   2082 N NH1   . ARG A 1 276 ? 134.578 219.441 166.098 1.00 124.50 ? 281 ARG M NH1   1 
ATOM   2083 N NH2   . ARG A 1 276 ? 136.257 220.937 166.526 1.00 124.50 ? 281 ARG M NH2   1 
ATOM   2084 N N     . ASP A 1 277 ? 140.292 215.629 167.791 1.00 121.54 ? 282 ASP M N     1 
ATOM   2085 C CA    . ASP A 1 277 ? 140.458 215.052 169.116 1.00 121.54 ? 282 ASP M CA    1 
ATOM   2086 C C     . ASP A 1 277 ? 139.074 214.715 169.667 1.00 121.54 ? 282 ASP M C     1 
ATOM   2087 O O     . ASP A 1 277 ? 138.078 214.715 168.941 1.00 121.54 ? 282 ASP M O     1 
ATOM   2088 C CB    . ASP A 1 277 ? 141.230 216.017 170.011 1.00 121.54 ? 282 ASP M CB    1 
ATOM   2089 C CG    . ASP A 1 277 ? 141.873 215.330 171.195 1.00 121.54 ? 282 ASP M CG    1 
ATOM   2090 O OD1   . ASP A 1 277 ? 141.346 214.290 171.640 1.00 121.54 ? 282 ASP M OD1   1 
ATOM   2091 O OD2   . ASP A 1 277 ? 142.904 215.832 171.680 1.00 121.54 ? 282 ASP M OD2   1 
ATOM   2092 N N     . TYR A 1 278 ? 138.993 214.418 170.959 1.00 120.52 ? 283 TYR M N     1 
ATOM   2093 C CA    . TYR A 1 278 ? 137.708 214.139 171.575 1.00 120.52 ? 283 TYR M CA    1 
ATOM   2094 C C     . TYR A 1 278 ? 136.818 215.379 171.553 1.00 120.52 ? 283 TYR M C     1 
ATOM   2095 O O     . TYR A 1 278 ? 137.284 216.512 171.407 1.00 120.52 ? 283 TYR M O     1 
ATOM   2096 C CB    . TYR A 1 278 ? 137.899 213.650 173.007 1.00 120.52 ? 283 TYR M CB    1 
ATOM   2097 C CG    . TYR A 1 278 ? 138.425 212.244 173.091 1.00 120.52 ? 283 TYR M CG    1 
ATOM   2098 C CD1   . TYR A 1 278 ? 137.564 211.160 173.048 1.00 120.52 ? 283 TYR M CD1   1 
ATOM   2099 C CD2   . TYR A 1 278 ? 139.784 211.998 173.210 1.00 120.52 ? 283 TYR M CD2   1 
ATOM   2100 C CE1   . TYR A 1 278 ? 138.041 209.871 173.122 1.00 120.52 ? 283 TYR M CE1   1 
ATOM   2101 C CE2   . TYR A 1 278 ? 140.270 210.714 173.285 1.00 120.52 ? 283 TYR M CE2   1 
ATOM   2102 C CZ    . TYR A 1 278 ? 139.395 209.654 173.242 1.00 120.52 ? 283 TYR M CZ    1 
ATOM   2103 O OH    . TYR A 1 278 ? 139.875 208.371 173.314 1.00 120.52 ? 283 TYR M OH    1 
ATOM   2104 N N     . HIS A 1 279 ? 135.511 215.149 171.699 1.00 123.13 ? 284 HIS M N     1 
ATOM   2105 C CA    . HIS A 1 279 ? 134.549 216.239 171.584 1.00 123.13 ? 284 HIS M CA    1 
ATOM   2106 C C     . HIS A 1 279 ? 134.705 217.276 172.685 1.00 123.13 ? 284 HIS M C     1 
ATOM   2107 O O     . HIS A 1 279 ? 134.391 218.451 172.458 1.00 123.13 ? 284 HIS M O     1 
ATOM   2108 C CB    . HIS A 1 279 ? 133.122 215.689 171.613 1.00 123.13 ? 284 HIS M CB    1 
ATOM   2109 C CG    . HIS A 1 279 ? 132.803 214.769 170.478 1.00 123.13 ? 284 HIS M CG    1 
ATOM   2110 N ND1   . HIS A 1 279 ? 133.479 214.803 169.279 1.00 123.13 ? 284 HIS M ND1   1 
ATOM   2111 C CD2   . HIS A 1 279 ? 131.880 213.784 170.362 1.00 123.13 ? 284 HIS M CD2   1 
ATOM   2112 C CE1   . HIS A 1 279 ? 132.986 213.881 168.471 1.00 123.13 ? 284 HIS M CE1   1 
ATOM   2113 N NE2   . HIS A 1 279 ? 132.015 213.249 169.105 1.00 123.13 ? 284 HIS M NE2   1 
ATOM   2114 N N     . ILE A 1 280 ? 135.195 216.873 173.858 1.00 121.38 ? 285 ILE M N     1 
ATOM   2115 C CA    . ILE A 1 280 ? 135.077 217.713 175.044 1.00 121.38 ? 285 ILE M CA    1 
ATOM   2116 C C     . ILE A 1 280 ? 135.863 218.999 174.868 1.00 121.38 ? 285 ILE M C     1 
ATOM   2117 O O     . ILE A 1 280 ? 135.422 220.072 175.280 1.00 121.38 ? 285 ILE M O     1 
ATOM   2118 C CB    . ILE A 1 280 ? 135.550 216.957 176.293 1.00 121.38 ? 285 ILE M CB    1 
ATOM   2119 C CG1   . ILE A 1 280 ? 135.007 215.541 176.295 1.00 121.38 ? 285 ILE M CG1   1 
ATOM   2120 C CG2   . ILE A 1 280 ? 135.125 217.693 177.540 1.00 121.38 ? 285 ILE M CG2   1 
ATOM   2121 C CD1   . ILE A 1 280 ? 136.055 214.551 175.892 1.00 121.38 ? 285 ILE M CD1   1 
ATOM   2122 N N     . PHE A 1 281 ? 137.063 218.902 174.300 1.00 122.02 ? 286 PHE M N     1 
ATOM   2123 C CA    . PHE A 1 281 ? 137.893 220.091 174.150 1.00 122.02 ? 286 PHE M CA    1 
ATOM   2124 C C     . PHE A 1 281 ? 137.196 221.134 173.292 1.00 122.02 ? 286 PHE M C     1 
ATOM   2125 O O     . PHE A 1 281 ? 137.254 222.334 173.582 1.00 122.02 ? 286 PHE M O     1 
ATOM   2126 C CB    . PHE A 1 281 ? 139.250 219.710 173.555 1.00 122.02 ? 286 PHE M CB    1 
ATOM   2127 C CG    . PHE A 1 281 ? 140.014 218.728 174.392 1.00 122.02 ? 286 PHE M CG    1 
ATOM   2128 C CD1   . PHE A 1 281 ? 140.918 219.167 175.339 1.00 122.02 ? 286 PHE M CD1   1 
ATOM   2129 C CD2   . PHE A 1 281 ? 139.810 217.368 174.247 1.00 122.02 ? 286 PHE M CD2   1 
ATOM   2130 C CE1   . PHE A 1 281 ? 141.609 218.273 176.115 1.00 122.02 ? 286 PHE M CE1   1 
ATOM   2131 C CE2   . PHE A 1 281 ? 140.500 216.468 175.026 1.00 122.02 ? 286 PHE M CE2   1 
ATOM   2132 C CZ    . PHE A 1 281 ? 141.399 216.923 175.961 1.00 122.02 ? 286 PHE M CZ    1 
ATOM   2133 N N     . TYR A 1 282 ? 136.504 220.688 172.248 1.00 123.80 ? 287 TYR M N     1 
ATOM   2134 C CA    . TYR A 1 282 ? 135.776 221.614 171.392 1.00 123.80 ? 287 TYR M CA    1 
ATOM   2135 C C     . TYR A 1 282 ? 134.543 222.163 172.095 1.00 123.80 ? 287 TYR M C     1 
ATOM   2136 O O     . TYR A 1 282 ? 134.243 223.358 171.994 1.00 123.80 ? 287 TYR M O     1 
ATOM   2137 C CB    . TYR A 1 282 ? 135.402 220.900 170.100 1.00 123.80 ? 287 TYR M CB    1 
ATOM   2138 C CG    . TYR A 1 282 ? 136.571 220.151 169.519 1.00 123.80 ? 287 TYR M CG    1 
ATOM   2139 C CD1   . TYR A 1 282 ? 137.793 220.780 169.338 1.00 123.80 ? 287 TYR M CD1   1 
ATOM   2140 C CD2   . TYR A 1 282 ? 136.466 218.812 169.179 1.00 123.80 ? 287 TYR M CD2   1 
ATOM   2141 C CE1   . TYR A 1 282 ? 138.864 220.109 168.811 1.00 123.80 ? 287 TYR M CE1   1 
ATOM   2142 C CE2   . TYR A 1 282 ? 137.540 218.130 168.653 1.00 123.80 ? 287 TYR M CE2   1 
ATOM   2143 C CZ    . TYR A 1 282 ? 138.738 218.784 168.474 1.00 123.80 ? 287 TYR M CZ    1 
ATOM   2144 O OH    . TYR A 1 282 ? 139.817 218.114 167.950 1.00 123.80 ? 287 TYR M OH    1 
ATOM   2145 N N     . GLN A 1 283 ? 133.818 221.305 172.813 1.00 124.87 ? 288 GLN M N     1 
ATOM   2146 C CA    . GLN A 1 283 ? 132.649 221.772 173.549 1.00 124.87 ? 288 GLN M CA    1 
ATOM   2147 C C     . GLN A 1 283 ? 133.036 222.835 174.566 1.00 124.87 ? 288 GLN M C     1 
ATOM   2148 O O     . GLN A 1 283 ? 132.332 223.836 174.726 1.00 124.87 ? 288 GLN M O     1 
ATOM   2149 C CB    . GLN A 1 283 ? 131.949 220.599 174.230 1.00 124.87 ? 288 GLN M CB    1 
ATOM   2150 C CG    . GLN A 1 283 ? 131.406 219.574 173.257 1.00 124.87 ? 288 GLN M CG    1 
ATOM   2151 C CD    . GLN A 1 283 ? 130.988 218.290 173.936 1.00 124.87 ? 288 GLN M CD    1 
ATOM   2152 O OE1   . GLN A 1 283 ? 131.140 218.137 175.144 1.00 124.87 ? 288 GLN M OE1   1 
ATOM   2153 N NE2   . GLN A 1 283 ? 130.447 217.361 173.162 1.00 124.87 ? 288 GLN M NE2   1 
ATOM   2154 N N     . ILE A 1 284 ? 134.156 222.641 175.260 1.00 123.85 ? 289 ILE M N     1 
ATOM   2155 C CA    . ILE A 1 284 ? 134.668 223.685 176.141 1.00 123.85 ? 289 ILE M CA    1 
ATOM   2156 C C     . ILE A 1 284 ? 135.081 224.901 175.329 1.00 123.85 ? 289 ILE M C     1 
ATOM   2157 O O     . ILE A 1 284 ? 134.885 226.045 175.754 1.00 123.85 ? 289 ILE M O     1 
ATOM   2158 C CB    . ILE A 1 284 ? 135.835 223.156 176.996 1.00 123.85 ? 289 ILE M CB    1 
ATOM   2159 C CG1   . ILE A 1 284 ? 135.469 221.826 177.661 1.00 123.85 ? 289 ILE M CG1   1 
ATOM   2160 C CG2   . ILE A 1 284 ? 136.252 224.188 178.023 1.00 123.85 ? 289 ILE M CG2   1 
ATOM   2161 C CD1   . ILE A 1 284 ? 134.194 221.862 178.466 1.00 123.85 ? 289 ILE M CD1   1 
ATOM   2162 N N     . LEU A 1 285 ? 135.650 224.679 174.146 1.00 125.07 ? 290 LEU M N     1 
ATOM   2163 C CA    . LEU A 1 285 ? 136.024 225.789 173.283 1.00 125.07 ? 290 LEU M CA    1 
ATOM   2164 C C     . LEU A 1 285 ? 134.824 226.539 172.727 1.00 125.07 ? 290 LEU M C     1 
ATOM   2165 O O     . LEU A 1 285 ? 135.008 227.608 172.136 1.00 125.07 ? 290 LEU M O     1 
ATOM   2166 C CB    . LEU A 1 285 ? 136.894 225.287 172.136 1.00 125.07 ? 290 LEU M CB    1 
ATOM   2167 C CG    . LEU A 1 285 ? 138.389 225.511 172.328 1.00 125.07 ? 290 LEU M CG    1 
ATOM   2168 C CD1   . LEU A 1 285 ? 139.134 225.046 171.102 1.00 125.07 ? 290 LEU M CD1   1 
ATOM   2169 C CD2   . LEU A 1 285 ? 138.671 226.978 172.611 1.00 125.07 ? 290 LEU M CD2   1 
ATOM   2170 N N     . SER A 1 286 ? 133.615 226.010 172.888 1.00 128.13 ? 291 SER M N     1 
ATOM   2171 C CA    . SER A 1 286 ? 132.413 226.780 172.599 1.00 128.13 ? 291 SER M CA    1 
ATOM   2172 C C     . SER A 1 286 ? 132.284 227.902 173.619 1.00 128.13 ? 291 SER M C     1 
ATOM   2173 O O     . SER A 1 286 ? 132.208 227.647 174.825 1.00 128.13 ? 291 SER M O     1 
ATOM   2174 C CB    . SER A 1 286 ? 131.182 225.880 172.633 1.00 128.13 ? 291 SER M CB    1 
ATOM   2175 O OG    . SER A 1 286 ? 130.023 226.636 172.922 1.00 128.13 ? 291 SER M OG    1 
ATOM   2176 N N     . ASN A 1 287 ? 132.256 229.145 173.141 1.00 128.11 ? 292 ASN M N     1 
ATOM   2177 C CA    . ASN A 1 287 ? 132.263 230.285 174.046 1.00 128.11 ? 292 ASN M CA    1 
ATOM   2178 C C     . ASN A 1 287 ? 130.949 230.476 174.790 1.00 128.11 ? 292 ASN M C     1 
ATOM   2179 O O     . ASN A 1 287 ? 130.849 231.419 175.582 1.00 128.11 ? 292 ASN M O     1 
ATOM   2180 C CB    . ASN A 1 287 ? 132.606 231.560 173.282 1.00 128.11 ? 292 ASN M CB    1 
ATOM   2181 C CG    . ASN A 1 287 ? 133.171 232.636 174.181 1.00 128.11 ? 292 ASN M CG    1 
ATOM   2182 O OD1   . ASN A 1 287 ? 133.581 232.362 175.308 1.00 128.11 ? 292 ASN M OD1   1 
ATOM   2183 N ND2   . ASN A 1 287 ? 133.194 233.870 173.690 1.00 128.11 ? 292 ASN M ND2   1 
ATOM   2184 N N     . LYS A 1 288 ? 129.948 229.617 174.572 1.00 129.51 ? 293 LYS M N     1 
ATOM   2185 C CA    . LYS A 1 288 ? 128.665 229.805 175.242 1.00 129.51 ? 293 LYS M CA    1 
ATOM   2186 C C     . LYS A 1 288 ? 128.793 229.773 176.759 1.00 129.51 ? 293 LYS M C     1 
ATOM   2187 O O     . LYS A 1 288 ? 127.904 230.275 177.455 1.00 129.51 ? 293 LYS M O     1 
ATOM   2188 C CB    . LYS A 1 288 ? 127.653 228.755 174.768 1.00 129.51 ? 293 LYS M CB    1 
ATOM   2189 C CG    . LYS A 1 288 ? 126.238 229.018 175.274 1.00 129.51 ? 293 LYS M CG    1 
ATOM   2190 C CD    . LYS A 1 288 ? 125.160 228.379 174.417 1.00 129.51 ? 293 LYS M CD    1 
ATOM   2191 C CE    . LYS A 1 288 ? 125.244 226.876 174.439 1.00 129.51 ? 293 LYS M CE    1 
ATOM   2192 N NZ    . LYS A 1 288 ? 123.967 226.244 174.003 1.00 129.51 ? 293 LYS M NZ    1 
ATOM   2193 N N     . LYS A 1 289 ? 129.883 229.223 177.288 1.00 128.22 ? 294 LYS M N     1 
ATOM   2194 C CA    . LYS A 1 289 ? 130.230 229.347 178.698 1.00 128.22 ? 294 LYS M CA    1 
ATOM   2195 C C     . LYS A 1 289 ? 131.478 230.210 178.815 1.00 128.22 ? 294 LYS M C     1 
ATOM   2196 O O     . LYS A 1 289 ? 132.594 229.685 178.923 1.00 128.22 ? 294 LYS M O     1 
ATOM   2197 C CB    . LYS A 1 289 ? 130.459 227.974 179.331 1.00 128.22 ? 294 LYS M CB    1 
ATOM   2198 C CG    . LYS A 1 289 ? 129.223 227.349 179.933 1.00 128.22 ? 294 LYS M CG    1 
ATOM   2199 C CD    . LYS A 1 289 ? 129.602 226.174 180.811 1.00 128.22 ? 294 LYS M CD    1 
ATOM   2200 C CE    . LYS A 1 289 ? 128.489 225.810 181.763 1.00 128.22 ? 294 LYS M CE    1 
ATOM   2201 N NZ    . LYS A 1 289 ? 128.267 226.886 182.760 1.00 128.22 ? 294 LYS M NZ    1 
ATOM   2202 N N     . PRO A 1 290 ? 131.354 231.538 178.792 1.00 127.22 ? 295 PRO M N     1 
ATOM   2203 C CA    . PRO A 1 290 ? 132.551 232.377 178.949 1.00 127.22 ? 295 PRO M CA    1 
ATOM   2204 C C     . PRO A 1 290 ? 133.153 232.301 180.336 1.00 127.22 ? 295 PRO M C     1 
ATOM   2205 O O     . PRO A 1 290 ? 134.329 232.655 180.503 1.00 127.22 ? 295 PRO M O     1 
ATOM   2206 C CB    . PRO A 1 290 ? 132.038 233.788 178.634 1.00 127.22 ? 295 PRO M CB    1 
ATOM   2207 C CG    . PRO A 1 290 ? 130.586 233.732 178.959 1.00 127.22 ? 295 PRO M CG    1 
ATOM   2208 C CD    . PRO A 1 290 ? 130.131 232.340 178.621 1.00 127.22 ? 295 PRO M CD    1 
ATOM   2209 N N     . GLU A 1 291 ? 132.395 231.846 181.336 1.00 126.24 ? 296 GLU M N     1 
ATOM   2210 C CA    . GLU A 1 291 ? 132.969 231.702 182.666 1.00 126.24 ? 296 GLU M CA    1 
ATOM   2211 C C     . GLU A 1 291 ? 134.031 230.609 182.683 1.00 126.24 ? 296 GLU M C     1 
ATOM   2212 O O     . GLU A 1 291 ? 135.069 230.761 183.332 1.00 126.24 ? 296 GLU M O     1 
ATOM   2213 C CB    . GLU A 1 291 ? 131.873 231.432 183.701 1.00 126.24 ? 296 GLU M CB    1 
ATOM   2214 C CG    . GLU A 1 291 ? 131.293 230.018 183.718 1.00 126.24 ? 296 GLU M CG    1 
ATOM   2215 C CD    . GLU A 1 291 ? 130.266 229.782 182.628 1.00 126.24 ? 296 GLU M CD    1 
ATOM   2216 O OE1   . GLU A 1 291 ? 130.286 230.513 181.615 1.00 126.24 ? 296 GLU M OE1   1 
ATOM   2217 O OE2   . GLU A 1 291 ? 129.424 228.877 182.794 1.00 126.24 ? 296 GLU M OE2   1 
ATOM   2218 N N     . LEU A 1 292 ? 133.818 229.524 181.938 1.00 123.78 ? 297 LEU M N     1 
ATOM   2219 C CA    . LEU A 1 292 ? 134.836 228.481 181.869 1.00 123.78 ? 297 LEU M CA    1 
ATOM   2220 C C     . LEU A 1 292 ? 136.113 229.010 181.232 1.00 123.78 ? 297 LEU M C     1 
ATOM   2221 O O     . LEU A 1 292 ? 137.217 228.764 181.730 1.00 123.78 ? 297 LEU M O     1 
ATOM   2222 C CB    . LEU A 1 292 ? 134.308 227.269 181.103 1.00 123.78 ? 297 LEU M CB    1 
ATOM   2223 C CG    . LEU A 1 292 ? 133.325 226.394 181.882 1.00 123.78 ? 297 LEU M CG    1 
ATOM   2224 C CD1   . LEU A 1 292 ? 133.167 225.037 181.219 1.00 123.78 ? 297 LEU M CD1   1 
ATOM   2225 C CD2   . LEU A 1 292 ? 133.760 226.237 183.326 1.00 123.78 ? 297 LEU M CD2   1 
ATOM   2226 N N     . LEU A 1 293 ? 135.983 229.760 180.140 1.00 123.04 ? 298 LEU M N     1 
ATOM   2227 C CA    . LEU A 1 293 ? 137.171 230.266 179.466 1.00 123.04 ? 298 LEU M CA    1 
ATOM   2228 C C     . LEU A 1 293 ? 137.912 231.280 180.327 1.00 123.04 ? 298 LEU M C     1 
ATOM   2229 O O     . LEU A 1 293 ? 139.144 231.234 180.424 1.00 123.04 ? 298 LEU M O     1 
ATOM   2230 C CB    . LEU A 1 293 ? 136.798 230.874 178.118 1.00 123.04 ? 298 LEU M CB    1 
ATOM   2231 C CG    . LEU A 1 293 ? 136.945 229.907 176.946 1.00 123.04 ? 298 LEU M CG    1 
ATOM   2232 C CD1   . LEU A 1 293 ? 135.934 228.778 177.050 1.00 123.04 ? 298 LEU M CD1   1 
ATOM   2233 C CD2   . LEU A 1 293 ? 136.820 230.632 175.617 1.00 123.04 ? 298 LEU M CD2   1 
ATOM   2234 N N     . ASP A 1 294 ? 137.194 232.202 180.965 1.00 124.48 ? 299 ASP M N     1 
ATOM   2235 C CA    . ASP A 1 294 ? 137.925 233.191 181.742 1.00 124.48 ? 299 ASP M CA    1 
ATOM   2236 C C     . ASP A 1 294 ? 138.393 232.649 183.085 1.00 124.48 ? 299 ASP M C     1 
ATOM   2237 O O     . ASP A 1 294 ? 139.222 233.295 183.734 1.00 124.48 ? 299 ASP M O     1 
ATOM   2238 C CB    . ASP A 1 294 ? 137.094 234.474 181.930 1.00 124.48 ? 299 ASP M CB    1 
ATOM   2239 C CG    . ASP A 1 294 ? 136.058 234.370 183.035 1.00 124.48 ? 299 ASP M CG    1 
ATOM   2240 O OD1   . ASP A 1 294 ? 135.531 233.274 183.276 1.00 124.48 ? 299 ASP M OD1   1 
ATOM   2241 O OD2   . ASP A 1 294 ? 135.761 235.407 183.663 1.00 124.48 ? 299 ASP M OD2   1 
ATOM   2242 N N     . MET A 1 295 ? 137.904 231.482 183.515 1.00 123.29 ? 300 MET M N     1 
ATOM   2243 C CA    . MET A 1 295 ? 138.464 230.852 184.701 1.00 123.29 ? 300 MET M CA    1 
ATOM   2244 C C     . MET A 1 295 ? 139.555 229.841 184.374 1.00 123.29 ? 300 MET M C     1 
ATOM   2245 O O     . MET A 1 295 ? 140.278 229.419 185.282 1.00 123.29 ? 300 MET M O     1 
ATOM   2246 C CB    . MET A 1 295 ? 137.372 230.148 185.509 1.00 123.29 ? 300 MET M CB    1 
ATOM   2247 C CG    . MET A 1 295 ? 136.845 228.892 184.849 1.00 123.29 ? 300 MET M CG    1 
ATOM   2248 S SD    . MET A 1 295 ? 136.189 227.702 186.025 1.00 123.29 ? 300 MET M SD    1 
ATOM   2249 C CE    . MET A 1 295 ? 137.566 226.572 186.115 1.00 123.29 ? 300 MET M CE    1 
ATOM   2250 N N     . LEU A 1 296 ? 139.672 229.424 183.112 1.00 120.19 ? 301 LEU M N     1 
ATOM   2251 C CA    . LEU A 1 296 ? 140.712 228.496 182.690 1.00 120.19 ? 301 LEU M CA    1 
ATOM   2252 C C     . LEU A 1 296 ? 141.780 229.126 181.813 1.00 120.19 ? 301 LEU M C     1 
ATOM   2253 O O     . LEU A 1 296 ? 142.661 228.408 181.340 1.00 120.19 ? 301 LEU M O     1 
ATOM   2254 C CB    . LEU A 1 296 ? 140.094 227.324 181.940 1.00 120.19 ? 301 LEU M CB    1 
ATOM   2255 C CG    . LEU A 1 296 ? 139.418 226.319 182.852 1.00 120.19 ? 301 LEU M CG    1 
ATOM   2256 C CD1   . LEU A 1 296 ? 139.096 225.040 182.108 1.00 120.19 ? 301 LEU M CD1   1 
ATOM   2257 C CD2   . LEU A 1 296 ? 140.340 226.075 184.011 1.00 120.19 ? 301 LEU M CD2   1 
ATOM   2258 N N     . LEU A 1 297 ? 141.712 230.432 181.562 1.00 119.47 ? 302 LEU M N     1 
ATOM   2259 C CA    . LEU A 1 297 ? 142.701 231.125 180.735 1.00 119.47 ? 302 LEU M CA    1 
ATOM   2260 C C     . LEU A 1 297 ? 142.721 230.571 179.315 1.00 119.47 ? 302 LEU M C     1 
ATOM   2261 O O     . LEU A 1 297 ? 143.746 230.601 178.633 1.00 119.47 ? 302 LEU M O     1 
ATOM   2262 C CB    . LEU A 1 297 ? 144.099 231.063 181.355 1.00 119.47 ? 302 LEU M CB    1 
ATOM   2263 C CG    . LEU A 1 297 ? 144.248 231.523 182.802 1.00 119.47 ? 302 LEU M CG    1 
ATOM   2264 C CD1   . LEU A 1 297 ? 144.236 230.343 183.749 1.00 119.47 ? 302 LEU M CD1   1 
ATOM   2265 C CD2   . LEU A 1 297 ? 145.525 232.326 182.962 1.00 119.47 ? 302 LEU M CD2   1 
ATOM   2266 N N     . ILE A 1 298 ? 141.579 230.068 178.861 1.00 121.82 ? 303 ILE M N     1 
ATOM   2267 C CA    . ILE A 1 298 ? 141.468 229.480 177.533 1.00 121.82 ? 303 ILE M CA    1 
ATOM   2268 C C     . ILE A 1 298 ? 141.079 230.577 176.551 1.00 121.82 ? 303 ILE M C     1 
ATOM   2269 O O     . ILE A 1 298 ? 139.960 231.092 176.589 1.00 121.82 ? 303 ILE M O     1 
ATOM   2270 C CB    . ILE A 1 298 ? 140.455 228.331 177.502 1.00 121.82 ? 303 ILE M CB    1 
ATOM   2271 C CG1   . ILE A 1 298 ? 140.918 227.176 178.387 1.00 121.82 ? 303 ILE M CG1   1 
ATOM   2272 C CG2   . ILE A 1 298 ? 140.239 227.852 176.079 1.00 121.82 ? 303 ILE M CG2   1 
ATOM   2273 C CD1   . ILE A 1 298 ? 139.807 226.220 178.742 1.00 121.82 ? 303 ILE M CD1   1 
ATOM   2274 N N     . THR A 1 299 ? 142.007 230.934 175.669 1.00 124.36 ? 304 THR M N     1 
ATOM   2275 C CA    . THR A 1 299 ? 141.702 231.863 174.592 1.00 124.36 ? 304 THR M CA    1 
ATOM   2276 C C     . THR A 1 299 ? 140.798 231.177 173.572 1.00 124.36 ? 304 THR M C     1 
ATOM   2277 O O     . THR A 1 299 ? 140.879 229.962 173.369 1.00 124.36 ? 304 THR M O     1 
ATOM   2278 C CB    . THR A 1 299 ? 143.001 232.348 173.944 1.00 124.36 ? 304 THR M CB    1 
ATOM   2279 O OG1   . THR A 1 299 ? 143.795 233.030 174.924 1.00 124.36 ? 304 THR M OG1   1 
ATOM   2280 C CG2   . THR A 1 299 ? 142.728 233.303 172.798 1.00 124.36 ? 304 THR M CG2   1 
ATOM   2281 N N     . ASN A 1 300 ? 139.917 231.958 172.942 1.00 126.17 ? 305 ASN M N     1 
ATOM   2282 C CA    . ASN A 1 300 ? 138.916 231.387 172.045 1.00 126.17 ? 305 ASN M CA    1 
ATOM   2283 C C     . ASN A 1 300 ? 139.531 230.655 170.858 1.00 126.17 ? 305 ASN M C     1 
ATOM   2284 O O     . ASN A 1 300 ? 138.898 229.747 170.311 1.00 126.17 ? 305 ASN M O     1 
ATOM   2285 C CB    . ASN A 1 300 ? 137.984 232.488 171.531 1.00 126.17 ? 305 ASN M CB    1 
ATOM   2286 C CG    . ASN A 1 300 ? 136.825 232.771 172.474 1.00 126.17 ? 305 ASN M CG    1 
ATOM   2287 O OD1   . ASN A 1 300 ? 135.878 231.990 172.570 1.00 126.17 ? 305 ASN M OD1   1 
ATOM   2288 N ND2   . ASN A 1 300 ? 136.894 233.899 173.172 1.00 126.17 ? 305 ASN M ND2   1 
ATOM   2289 N N     . ASN A 1 301 ? 140.753 231.007 170.466 1.00 125.41 ? 306 ASN M N     1 
ATOM   2290 C CA    . ASN A 1 301 ? 141.325 230.526 169.215 1.00 125.41 ? 306 ASN M CA    1 
ATOM   2291 C C     . ASN A 1 301 ? 141.758 229.074 169.359 1.00 125.41 ? 306 ASN M C     1 
ATOM   2292 O O     . ASN A 1 301 ? 142.669 228.787 170.145 1.00 125.41 ? 306 ASN M O     1 
ATOM   2293 C CB    . ASN A 1 301 ? 142.509 231.384 168.809 1.00 125.41 ? 306 ASN M CB    1 
ATOM   2294 C CG    . ASN A 1 301 ? 142.988 231.086 167.405 1.00 125.41 ? 306 ASN M CG    1 
ATOM   2295 O OD1   . ASN A 1 301 ? 142.291 230.441 166.623 1.00 125.41 ? 306 ASN M OD1   1 
ATOM   2296 N ND2   . ASN A 1 301 ? 144.183 231.563 167.074 1.00 125.41 ? 306 ASN M ND2   1 
ATOM   2297 N N     . PRO A 1 302 ? 141.150 228.138 168.626 1.00 125.37 ? 307 PRO M N     1 
ATOM   2298 C CA    . PRO A 1 302 ? 141.536 226.724 168.763 1.00 125.37 ? 307 PRO M CA    1 
ATOM   2299 C C     . PRO A 1 302 ? 142.899 226.398 168.183 1.00 125.37 ? 307 PRO M C     1 
ATOM   2300 O O     . PRO A 1 302 ? 143.508 225.409 168.606 1.00 125.37 ? 307 PRO M O     1 
ATOM   2301 C CB    . PRO A 1 302 ? 140.425 225.984 168.009 1.00 125.37 ? 307 PRO M CB    1 
ATOM   2302 C CG    . PRO A 1 302 ? 139.896 226.986 167.052 1.00 125.37 ? 307 PRO M CG    1 
ATOM   2303 C CD    . PRO A 1 302 ? 140.033 228.328 167.689 1.00 125.37 ? 307 PRO M CD    1 
ATOM   2304 N N     . TYR A 1 303 ? 143.394 227.186 167.226 1.00 125.45 ? 308 TYR M N     1 
ATOM   2305 C CA    . TYR A 1 303 ? 144.747 226.990 166.720 1.00 125.45 ? 308 TYR M CA    1 
ATOM   2306 C C     . TYR A 1 303 ? 145.798 227.221 167.791 1.00 125.45 ? 308 TYR M C     1 
ATOM   2307 O O     . TYR A 1 303 ? 146.971 226.898 167.577 1.00 125.45 ? 308 TYR M O     1 
ATOM   2308 C CB    . TYR A 1 303 ? 145.024 227.938 165.557 1.00 125.45 ? 308 TYR M CB    1 
ATOM   2309 C CG    . TYR A 1 303 ? 144.100 227.780 164.381 1.00 125.45 ? 308 TYR M CG    1 
ATOM   2310 C CD1   . TYR A 1 303 ? 143.595 226.535 164.025 1.00 125.45 ? 308 TYR M CD1   1 
ATOM   2311 C CD2   . TYR A 1 303 ? 143.727 228.884 163.624 1.00 125.45 ? 308 TYR M CD2   1 
ATOM   2312 C CE1   . TYR A 1 303 ? 142.748 226.397 162.942 1.00 125.45 ? 308 TYR M CE1   1 
ATOM   2313 C CE2   . TYR A 1 303 ? 142.882 228.757 162.547 1.00 125.45 ? 308 TYR M CE2   1 
ATOM   2314 C CZ    . TYR A 1 303 ? 142.393 227.515 162.209 1.00 125.45 ? 308 TYR M CZ    1 
ATOM   2315 O OH    . TYR A 1 303 ? 141.550 227.400 161.131 1.00 125.45 ? 308 TYR M OH    1 
ATOM   2316 N N     . ASP A 1 304 ? 145.409 227.792 168.927 1.00 122.71 ? 309 ASP M N     1 
ATOM   2317 C CA    . ASP A 1 304 ? 146.386 228.203 169.925 1.00 122.71 ? 309 ASP M CA    1 
ATOM   2318 C C     . ASP A 1 304 ? 147.029 227.000 170.602 1.00 122.71 ? 309 ASP M C     1 
ATOM   2319 O O     . ASP A 1 304 ? 148.189 227.064 171.020 1.00 122.71 ? 309 ASP M O     1 
ATOM   2320 C CB    . ASP A 1 304 ? 145.708 229.105 170.953 1.00 122.71 ? 309 ASP M CB    1 
ATOM   2321 C CG    . ASP A 1 304 ? 146.591 230.240 171.405 1.00 122.71 ? 309 ASP M CG    1 
ATOM   2322 O OD1   . ASP A 1 304 ? 147.467 230.659 170.621 1.00 122.71 ? 309 ASP M OD1   1 
ATOM   2323 O OD2   . ASP A 1 304 ? 146.398 230.724 172.540 1.00 122.71 ? 309 ASP M OD2   1 
ATOM   2324 N N     . TYR A 1 305 ? 146.297 225.898 170.715 1.00 121.01 ? 310 TYR M N     1 
ATOM   2325 C CA    . TYR A 1 305 ? 146.703 224.782 171.558 1.00 121.01 ? 310 TYR M CA    1 
ATOM   2326 C C     . TYR A 1 305 ? 147.194 223.613 170.712 1.00 121.01 ? 310 TYR M C     1 
ATOM   2327 O O     . TYR A 1 305 ? 146.445 223.069 169.894 1.00 121.01 ? 310 TYR M O     1 
ATOM   2328 C CB    . TYR A 1 305 ? 145.534 224.377 172.452 1.00 121.01 ? 310 TYR M CB    1 
ATOM   2329 C CG    . TYR A 1 305 ? 145.038 225.558 173.245 1.00 121.01 ? 310 TYR M CG    1 
ATOM   2330 C CD1   . TYR A 1 305 ? 145.586 225.868 174.476 1.00 121.01 ? 310 TYR M CD1   1 
ATOM   2331 C CD2   . TYR A 1 305 ? 144.062 226.395 172.739 1.00 121.01 ? 310 TYR M CD2   1 
ATOM   2332 C CE1   . TYR A 1 305 ? 145.155 226.958 175.194 1.00 121.01 ? 310 TYR M CE1   1 
ATOM   2333 C CE2   . TYR A 1 305 ? 143.627 227.489 173.446 1.00 121.01 ? 310 TYR M CE2   1 
ATOM   2334 C CZ    . TYR A 1 305 ? 144.174 227.767 174.674 1.00 121.01 ? 310 TYR M CZ    1 
ATOM   2335 O OH    . TYR A 1 305 ? 143.734 228.861 175.381 1.00 121.01 ? 310 TYR M OH    1 
ATOM   2336 N N     . ALA A 1 306 ? 148.448 223.211 170.946 1.00 116.61 ? 311 ALA M N     1 
ATOM   2337 C CA    . ALA A 1 306 ? 149.157 222.339 170.016 1.00 116.61 ? 311 ALA M CA    1 
ATOM   2338 C C     . ALA A 1 306 ? 148.682 220.899 170.080 1.00 116.61 ? 311 ALA M C     1 
ATOM   2339 O O     . ALA A 1 306 ? 148.729 220.196 169.066 1.00 116.61 ? 311 ALA M O     1 
ATOM   2340 C CB    . ALA A 1 306 ? 150.660 222.398 170.281 1.00 116.61 ? 311 ALA M CB    1 
ATOM   2341 N N     . PHE A 1 307 ? 148.240 220.434 171.248 1.00 113.52 ? 312 PHE M N     1 
ATOM   2342 C CA    . PHE A 1 307 ? 147.740 219.069 171.342 1.00 113.52 ? 312 PHE M CA    1 
ATOM   2343 C C     . PHE A 1 307 ? 146.546 218.838 170.435 1.00 113.52 ? 312 PHE M C     1 
ATOM   2344 O O     . PHE A 1 307 ? 146.319 217.703 170.007 1.00 113.52 ? 312 PHE M O     1 
ATOM   2345 C CB    . PHE A 1 307 ? 147.349 218.740 172.779 1.00 113.52 ? 312 PHE M CB    1 
ATOM   2346 C CG    . PHE A 1 307 ? 148.505 218.374 173.652 1.00 113.52 ? 312 PHE M CG    1 
ATOM   2347 C CD1   . PHE A 1 307 ? 149.754 218.153 173.111 1.00 113.52 ? 312 PHE M CD1   1 
ATOM   2348 C CD2   . PHE A 1 307 ? 148.340 218.242 175.015 1.00 113.52 ? 312 PHE M CD2   1 
ATOM   2349 C CE1   . PHE A 1 307 ? 150.813 217.811 173.912 1.00 113.52 ? 312 PHE M CE1   1 
ATOM   2350 C CE2   . PHE A 1 307 ? 149.398 217.904 175.820 1.00 113.52 ? 312 PHE M CE2   1 
ATOM   2351 C CZ    . PHE A 1 307 ? 150.635 217.688 175.269 1.00 113.52 ? 312 PHE M CZ    1 
ATOM   2352 N N     . ILE A 1 308 ? 145.794 219.890 170.120 1.00 117.94 ? 313 ILE M N     1 
ATOM   2353 C CA    . ILE A 1 308 ? 144.538 219.775 169.400 1.00 117.94 ? 313 ILE M CA    1 
ATOM   2354 C C     . ILE A 1 308 ? 144.654 220.289 167.971 1.00 117.94 ? 313 ILE M C     1 
ATOM   2355 O O     . ILE A 1 308 ? 144.096 219.694 167.048 1.00 117.94 ? 313 ILE M O     1 
ATOM   2356 C CB    . ILE A 1 308 ? 143.423 220.519 170.157 1.00 117.94 ? 313 ILE M CB    1 
ATOM   2357 C CG1   . ILE A 1 308 ? 143.567 220.309 171.660 1.00 117.94 ? 313 ILE M CG1   1 
ATOM   2358 C CG2   . ILE A 1 308 ? 142.087 220.003 169.716 1.00 117.94 ? 313 ILE M CG2   1 
ATOM   2359 C CD1   . ILE A 1 308 ? 143.328 218.893 172.088 1.00 117.94 ? 313 ILE M CD1   1 
ATOM   2360 N N     . SER A 1 309 ? 145.387 221.386 167.771 1.00 119.55 ? 314 SER M N     1 
ATOM   2361 C CA    . SER A 1 309 ? 145.394 222.079 166.489 1.00 119.55 ? 314 SER M CA    1 
ATOM   2362 C C     . SER A 1 309 ? 145.876 221.214 165.333 1.00 119.55 ? 314 SER M C     1 
ATOM   2363 O O     . SER A 1 309 ? 145.617 221.557 164.174 1.00 119.55 ? 314 SER M O     1 
ATOM   2364 C CB    . SER A 1 309 ? 146.269 223.323 166.580 1.00 119.55 ? 314 SER M CB    1 
ATOM   2365 O OG    . SER A 1 309 ? 147.615 223.002 166.287 1.00 119.55 ? 314 SER M OG    1 
ATOM   2366 N N     . GLN A 1 310 ? 146.576 220.116 165.603 1.00 118.23 ? 315 GLN M N     1 
ATOM   2367 C CA    . GLN A 1 310 ? 147.049 219.275 164.511 1.00 118.23 ? 315 GLN M CA    1 
ATOM   2368 C C     . GLN A 1 310 ? 145.928 218.480 163.856 1.00 118.23 ? 315 GLN M C     1 
ATOM   2369 O O     . GLN A 1 310 ? 146.074 218.062 162.702 1.00 118.23 ? 315 GLN M O     1 
ATOM   2370 C CB    . GLN A 1 310 ? 148.146 218.330 165.001 1.00 118.23 ? 315 GLN M CB    1 
ATOM   2371 C CG    . GLN A 1 310 ? 147.857 217.691 166.332 1.00 118.23 ? 315 GLN M CG    1 
ATOM   2372 C CD    . GLN A 1 310 ? 148.966 216.770 166.777 1.00 118.23 ? 315 GLN M CD    1 
ATOM   2373 O OE1   . GLN A 1 310 ? 149.971 216.616 166.090 1.00 118.23 ? 315 GLN M OE1   1 
ATOM   2374 N NE2   . GLN A 1 310 ? 148.790 216.152 167.933 1.00 118.23 ? 315 GLN M NE2   1 
ATOM   2375 N N     . GLY A 1 311 ? 144.817 218.263 164.556 1.00 122.34 ? 316 GLY M N     1 
ATOM   2376 C CA    . GLY A 1 311 ? 143.665 217.616 163.969 1.00 122.34 ? 316 GLY M CA    1 
ATOM   2377 C C     . GLY A 1 311 ? 142.735 218.606 163.288 1.00 122.34 ? 316 GLY M C     1 
ATOM   2378 O O     . GLY A 1 311 ? 143.021 219.795 163.165 1.00 122.34 ? 316 GLY M O     1 
ATOM   2379 N N     . GLU A 1 312 ? 141.596 218.090 162.830 1.00 125.55 ? 317 GLU M N     1 
ATOM   2380 C CA    . GLU A 1 312 ? 140.581 218.955 162.243 1.00 125.55 ? 317 GLU M CA    1 
ATOM   2381 C C     . GLU A 1 312 ? 140.047 219.912 163.296 1.00 125.55 ? 317 GLU M C     1 
ATOM   2382 O O     . GLU A 1 312 ? 139.507 219.486 164.321 1.00 125.55 ? 317 GLU M O     1 
ATOM   2383 C CB    . GLU A 1 312 ? 139.438 218.134 161.655 1.00 125.55 ? 317 GLU M CB    1 
ATOM   2384 C CG    . GLU A 1 312 ? 139.797 217.417 160.377 1.00 125.55 ? 317 GLU M CG    1 
ATOM   2385 C CD    . GLU A 1 312 ? 140.180 218.367 159.267 1.00 125.55 ? 317 GLU M CD    1 
ATOM   2386 O OE1   . GLU A 1 312 ? 139.696 219.518 159.270 1.00 125.55 ? 317 GLU M OE1   1 
ATOM   2387 O OE2   . GLU A 1 312 ? 140.970 217.963 158.390 1.00 125.55 ? 317 GLU M OE2   1 
ATOM   2388 N N     . THR A 1 313 ? 140.189 221.210 163.032 1.00 126.18 ? 318 THR M N     1 
ATOM   2389 C CA    . THR A 1 313 ? 139.855 222.212 164.036 1.00 126.18 ? 318 THR M CA    1 
ATOM   2390 C C     . THR A 1 313 ? 138.372 222.172 164.378 1.00 126.18 ? 318 THR M C     1 
ATOM   2391 O O     . THR A 1 313 ? 137.991 221.886 165.517 1.00 126.18 ? 318 THR M O     1 
ATOM   2392 C CB    . THR A 1 313 ? 140.255 223.597 163.534 1.00 126.18 ? 318 THR M CB    1 
ATOM   2393 O OG1   . THR A 1 313 ? 141.536 223.524 162.897 1.00 126.18 ? 318 THR M OG1   1 
ATOM   2394 C CG2   . THR A 1 313 ? 140.334 224.553 164.687 1.00 126.18 ? 318 THR M CG2   1 
ATOM   2395 N N     . THR A 1 314 ? 137.517 222.446 163.397 1.00 128.95 ? 319 THR M N     1 
ATOM   2396 C CA    . THR A 1 314 ? 136.078 222.413 163.602 1.00 128.95 ? 319 THR M CA    1 
ATOM   2397 C C     . THR A 1 314 ? 135.412 221.832 162.366 1.00 128.95 ? 319 THR M C     1 
ATOM   2398 O O     . THR A 1 314 ? 135.867 222.040 161.238 1.00 128.95 ? 319 THR M O     1 
ATOM   2399 C CB    . THR A 1 314 ? 135.510 223.813 163.919 1.00 128.95 ? 319 THR M CB    1 
ATOM   2400 O OG1   . THR A 1 314 ? 134.142 223.699 164.335 1.00 128.95 ? 319 THR M OG1   1 
ATOM   2401 C CG2   . THR A 1 314 ? 135.602 224.740 162.708 1.00 128.95 ? 319 THR M CG2   1 
ATOM   2402 N N     . VAL A 1 315 ? 134.338 221.074 162.594 1.00 130.09 ? 320 VAL M N     1 
ATOM   2403 C CA    . VAL A 1 315 ? 133.563 220.470 161.519 1.00 130.09 ? 320 VAL M CA    1 
ATOM   2404 C C     . VAL A 1 315 ? 132.082 220.622 161.832 1.00 130.09 ? 320 VAL M C     1 
ATOM   2405 O O     . VAL A 1 315 ? 131.681 220.840 162.977 1.00 130.09 ? 320 VAL M O     1 
ATOM   2406 C CB    . VAL A 1 315 ? 133.898 218.978 161.296 1.00 130.09 ? 320 VAL M CB    1 
ATOM   2407 C CG1   . VAL A 1 315 ? 135.316 218.818 160.783 1.00 130.09 ? 320 VAL M CG1   1 
ATOM   2408 C CG2   . VAL A 1 315 ? 133.688 218.194 162.573 1.00 130.09 ? 320 VAL M CG2   1 
ATOM   2409 N N     . ALA A 1 316 ? 131.266 220.488 160.786 1.00 132.56 ? 321 ALA M N     1 
ATOM   2410 C CA    . ALA A 1 316 ? 129.819 220.563 160.923 1.00 132.56 ? 321 ALA M CA    1 
ATOM   2411 C C     . ALA A 1 316 ? 129.290 219.250 161.476 1.00 132.56 ? 321 ALA M C     1 
ATOM   2412 O O     . ALA A 1 316 ? 128.423 218.611 160.872 1.00 132.56 ? 321 ALA M O     1 
ATOM   2413 C CB    . ALA A 1 316 ? 129.166 220.883 159.579 1.00 132.56 ? 321 ALA M CB    1 
ATOM   2414 N N     . SER A 1 317 ? 129.814 218.841 162.629 1.00 133.38 ? 322 SER M N     1 
ATOM   2415 C CA    . SER A 1 317 ? 129.413 217.577 163.229 1.00 133.38 ? 322 SER M CA    1 
ATOM   2416 C C     . SER A 1 317 ? 128.077 217.714 163.946 1.00 133.38 ? 322 SER M C     1 
ATOM   2417 O O     . SER A 1 317 ? 127.079 217.100 163.553 1.00 133.38 ? 322 SER M O     1 
ATOM   2418 C CB    . SER A 1 317 ? 130.503 217.095 164.195 1.00 133.38 ? 322 SER M CB    1 
ATOM   2419 O OG    . SER A 1 317 ? 131.001 218.165 164.980 1.00 133.38 ? 322 SER M OG    1 
ATOM   2420 N N     . ILE A 1 318 ? 128.045 218.540 164.991 1.00 133.71 ? 323 ILE M N     1 
ATOM   2421 C CA    . ILE A 1 318 ? 126.861 218.752 165.810 1.00 133.71 ? 323 ILE M CA    1 
ATOM   2422 C C     . ILE A 1 318 ? 126.900 220.182 166.320 1.00 133.71 ? 323 ILE M C     1 
ATOM   2423 O O     . ILE A 1 318 ? 127.861 220.920 166.094 1.00 133.71 ? 323 ILE M O     1 
ATOM   2424 C CB    . ILE A 1 318 ? 126.773 217.769 167.004 1.00 133.71 ? 323 ILE M CB    1 
ATOM   2425 C CG1   . ILE A 1 318 ? 128.061 217.817 167.827 1.00 133.71 ? 323 ILE M CG1   1 
ATOM   2426 C CG2   . ILE A 1 318 ? 126.452 216.351 166.545 1.00 133.71 ? 323 ILE M CG2   1 
ATOM   2427 C CD1   . ILE A 1 318 ? 127.879 217.412 169.270 1.00 133.71 ? 323 ILE M CD1   1 
ATOM   2428 N N     . ASP A 1 319 ? 125.830 220.579 166.998 1.00 134.80 ? 324 ASP M N     1 
ATOM   2429 C CA    . ASP A 1 319 ? 125.813 221.837 167.736 1.00 134.80 ? 324 ASP M CA    1 
ATOM   2430 C C     . ASP A 1 319 ? 126.593 221.650 169.032 1.00 134.80 ? 324 ASP M C     1 
ATOM   2431 O O     . ASP A 1 319 ? 126.038 221.268 170.066 1.00 134.80 ? 324 ASP M O     1 
ATOM   2432 C CB    . ASP A 1 319 ? 124.373 222.278 167.972 1.00 134.80 ? 324 ASP M CB    1 
ATOM   2433 C CG    . ASP A 1 319 ? 123.521 221.188 168.588 1.00 134.80 ? 324 ASP M CG    1 
ATOM   2434 O OD1   . ASP A 1 319 ? 122.371 221.480 168.978 1.00 134.80 ? 324 ASP M OD1   1 
ATOM   2435 O OD2   . ASP A 1 319 ? 123.999 220.037 168.675 1.00 134.80 ? 324 ASP M OD2   1 
ATOM   2436 N N     . ASP A 1 320 ? 127.897 221.935 168.972 1.00 133.45 ? 325 ASP M N     1 
ATOM   2437 C CA    . ASP A 1 320 ? 128.793 221.633 170.084 1.00 133.45 ? 325 ASP M CA    1 
ATOM   2438 C C     . ASP A 1 320 ? 128.450 222.437 171.328 1.00 133.45 ? 325 ASP M C     1 
ATOM   2439 O O     . ASP A 1 320 ? 128.591 221.934 172.446 1.00 133.45 ? 325 ASP M O     1 
ATOM   2440 C CB    . ASP A 1 320 ? 130.235 221.900 169.669 1.00 133.45 ? 325 ASP M CB    1 
ATOM   2441 C CG    . ASP A 1 320 ? 130.424 223.290 169.090 1.00 133.45 ? 325 ASP M CG    1 
ATOM   2442 O OD1   . ASP A 1 320 ? 130.685 223.396 167.874 1.00 133.45 ? 325 ASP M OD1   1 
ATOM   2443 O OD2   . ASP A 1 320 ? 130.311 224.276 169.848 1.00 133.45 ? 325 ASP M OD2   1 
ATOM   2444 N N     . ALA A 1 321 ? 128.011 223.684 171.158 1.00 132.82 ? 326 ALA M N     1 
ATOM   2445 C CA    . ALA A 1 321 ? 127.594 224.489 172.301 1.00 132.82 ? 326 ALA M CA    1 
ATOM   2446 C C     . ALA A 1 321 ? 126.417 223.840 173.018 1.00 132.82 ? 326 ALA M C     1 
ATOM   2447 O O     . ALA A 1 321 ? 126.423 223.677 174.248 1.00 132.82 ? 326 ALA M O     1 
ATOM   2448 C CB    . ALA A 1 321 ? 127.237 225.897 171.828 1.00 132.82 ? 326 ALA M CB    1 
ATOM   2449 N N     . GLU A 1 322 ? 125.393 223.460 172.255 1.00 134.08 ? 327 GLU M N     1 
ATOM   2450 C CA    . GLU A 1 322 ? 124.257 222.772 172.846 1.00 134.08 ? 327 GLU M CA    1 
ATOM   2451 C C     . GLU A 1 322 ? 124.689 221.474 173.503 1.00 134.08 ? 327 GLU M C     1 
ATOM   2452 O O     . GLU A 1 322 ? 124.131 221.090 174.534 1.00 134.08 ? 327 GLU M O     1 
ATOM   2453 C CB    . GLU A 1 322 ? 123.191 222.510 171.782 1.00 134.08 ? 327 GLU M CB    1 
ATOM   2454 C CG    . GLU A 1 322 ? 121.901 221.856 172.291 1.00 134.08 ? 327 GLU M CG    1 
ATOM   2455 C CD    . GLU A 1 322 ? 122.030 220.359 172.524 1.00 134.08 ? 327 GLU M CD    1 
ATOM   2456 O OE1   . GLU A 1 322 ? 122.933 219.735 171.927 1.00 134.08 ? 327 GLU M OE1   1 
ATOM   2457 O OE2   . GLU A 1 322 ? 121.240 219.809 173.318 1.00 134.08 ? 327 GLU M OE2   1 
ATOM   2458 N N     . GLU A 1 323 ? 125.663 220.775 172.918 1.00 132.12 ? 328 GLU M N     1 
ATOM   2459 C CA    . GLU A 1 323 ? 126.095 219.519 173.518 1.00 132.12 ? 328 GLU M CA    1 
ATOM   2460 C C     . GLU A 1 323 ? 126.809 219.765 174.838 1.00 132.12 ? 328 GLU M C     1 
ATOM   2461 O O     . GLU A 1 323 ? 126.640 219.001 175.796 1.00 132.12 ? 328 GLU M O     1 
ATOM   2462 C CB    . GLU A 1 323 ? 126.985 218.747 172.551 1.00 132.12 ? 328 GLU M CB    1 
ATOM   2463 C CG    . GLU A 1 323 ? 127.064 217.283 172.908 1.00 132.12 ? 328 GLU M CG    1 
ATOM   2464 C CD    . GLU A 1 323 ? 125.711 216.729 173.294 1.00 132.12 ? 328 GLU M CD    1 
ATOM   2465 O OE1   . GLU A 1 323 ? 124.835 216.621 172.414 1.00 132.12 ? 328 GLU M OE1   1 
ATOM   2466 O OE2   . GLU A 1 323 ? 125.514 216.425 174.487 1.00 132.12 ? 328 GLU M OE2   1 
ATOM   2467 N N     . LEU A 1 324 ? 127.623 220.818 174.894 1.00 131.25 ? 329 LEU M N     1 
ATOM   2468 C CA    . LEU A 1 324 ? 128.182 221.271 176.161 1.00 131.25 ? 329 LEU M CA    1 
ATOM   2469 C C     . LEU A 1 324 ? 127.085 221.494 177.190 1.00 131.25 ? 329 LEU M C     1 
ATOM   2470 O O     . LEU A 1 324 ? 127.204 221.067 178.345 1.00 131.25 ? 329 LEU M O     1 
ATOM   2471 C CB    . LEU A 1 324 ? 128.982 222.556 175.942 1.00 131.25 ? 329 LEU M CB    1 
ATOM   2472 C CG    . LEU A 1 324 ? 129.383 223.354 177.181 1.00 131.25 ? 329 LEU M CG    1 
ATOM   2473 C CD1   . LEU A 1 324 ? 130.300 222.546 178.082 1.00 131.25 ? 329 LEU M CD1   1 
ATOM   2474 C CD2   . LEU A 1 324 ? 130.038 224.656 176.767 1.00 131.25 ? 329 LEU M CD2   1 
ATOM   2475 N N     . MET A 1 325 ? 125.998 222.148 176.781 1.00 131.88 ? 330 MET M N     1 
ATOM   2476 C CA    . MET A 1 325 ? 124.909 222.395 177.722 1.00 131.88 ? 330 MET M CA    1 
ATOM   2477 C C     . MET A 1 325 ? 124.236 221.099 178.155 1.00 131.88 ? 330 MET M C     1 
ATOM   2478 O O     . MET A 1 325 ? 123.912 220.930 179.334 1.00 131.88 ? 330 MET M O     1 
ATOM   2479 C CB    . MET A 1 325 ? 123.886 223.348 177.115 1.00 131.88 ? 330 MET M CB    1 
ATOM   2480 C CG    . MET A 1 325 ? 124.416 224.743 176.949 1.00 131.88 ? 330 MET M CG    1 
ATOM   2481 S SD    . MET A 1 325 ? 125.281 225.320 178.418 1.00 131.88 ? 330 MET M SD    1 
ATOM   2482 C CE    . MET A 1 325 ? 126.664 226.168 177.666 1.00 131.88 ? 330 MET M CE    1 
ATOM   2483 N N     . ALA A 1 326 ? 124.009 220.180 177.217 1.00 131.34 ? 331 ALA M N     1 
ATOM   2484 C CA    . ALA A 1 326 ? 123.371 218.913 177.559 1.00 131.34 ? 331 ALA M CA    1 
ATOM   2485 C C     . ALA A 1 326 ? 124.230 218.117 178.528 1.00 131.34 ? 331 ALA M C     1 
ATOM   2486 O O     . ALA A 1 326 ? 123.715 217.486 179.459 1.00 131.34 ? 331 ALA M O     1 
ATOM   2487 C CB    . ALA A 1 326 ? 123.096 218.098 176.295 1.00 131.34 ? 331 ALA M CB    1 
ATOM   2488 N N     . THR A 1 327 ? 125.548 218.152 178.337 1.00 130.65 ? 332 THR M N     1 
ATOM   2489 C CA    . THR A 1 327 ? 126.445 217.468 179.258 1.00 130.65 ? 332 THR M CA    1 
ATOM   2490 C C     . THR A 1 327 ? 126.443 218.129 180.627 1.00 130.65 ? 332 THR M C     1 
ATOM   2491 O O     . THR A 1 327 ? 126.430 217.439 181.648 1.00 130.65 ? 332 THR M O     1 
ATOM   2492 C CB    . THR A 1 327 ? 127.859 217.436 178.687 1.00 130.65 ? 332 THR M CB    1 
ATOM   2493 O OG1   . THR A 1 327 ? 128.135 218.680 178.033 1.00 130.65 ? 332 THR M OG1   1 
ATOM   2494 C CG2   . THR A 1 327 ? 128.011 216.288 177.699 1.00 130.65 ? 332 THR M CG2   1 
ATOM   2495 N N     . ASP A 1 328 ? 126.460 219.461 180.676 1.00 130.00 ? 333 ASP M N     1 
ATOM   2496 C CA    . ASP A 1 328 ? 126.398 220.136 181.969 1.00 130.00 ? 333 ASP M CA    1 
ATOM   2497 C C     . ASP A 1 328 ? 125.095 219.818 182.691 1.00 130.00 ? 333 ASP M C     1 
ATOM   2498 O O     . ASP A 1 328 ? 125.081 219.643 183.914 1.00 130.00 ? 333 ASP M O     1 
ATOM   2499 C CB    . ASP A 1 328 ? 126.553 221.642 181.782 1.00 130.00 ? 333 ASP M CB    1 
ATOM   2500 C CG    . ASP A 1 328 ? 127.821 222.003 181.057 1.00 130.00 ? 333 ASP M CG    1 
ATOM   2501 O OD1   . ASP A 1 328 ? 128.822 221.284 181.233 1.00 130.00 ? 333 ASP M OD1   1 
ATOM   2502 O OD2   . ASP A 1 328 ? 127.821 222.997 180.305 1.00 130.00 ? 333 ASP M OD2   1 
ATOM   2503 N N     . ASN A 1 329 ? 123.993 219.734 181.947 1.00 132.38 ? 334 ASN M N     1 
ATOM   2504 C CA    . ASN A 1 329 ? 122.717 219.363 182.546 1.00 132.38 ? 334 ASN M CA    1 
ATOM   2505 C C     . ASN A 1 329 ? 122.769 217.946 183.098 1.00 132.38 ? 334 ASN M C     1 
ATOM   2506 O O     . ASN A 1 329 ? 122.364 217.699 184.241 1.00 132.38 ? 334 ASN M O     1 
ATOM   2507 C CB    . ASN A 1 329 ? 121.596 219.504 181.516 1.00 132.38 ? 334 ASN M CB    1 
ATOM   2508 C CG    . ASN A 1 329 ? 121.477 220.914 180.977 1.00 132.38 ? 334 ASN M CG    1 
ATOM   2509 O OD1   . ASN A 1 329 ? 122.280 221.786 181.310 1.00 132.38 ? 334 ASN M OD1   1 
ATOM   2510 N ND2   . ASN A 1 329 ? 120.480 221.145 180.130 1.00 132.38 ? 334 ASN M ND2   1 
ATOM   2511 N N     . ALA A 1 330 ? 123.275 217.001 182.299 1.00 130.78 ? 335 ALA M N     1 
ATOM   2512 C CA    . ALA A 1 330 ? 123.423 215.628 182.771 1.00 130.78 ? 335 ALA M CA    1 
ATOM   2513 C C     . ALA A 1 330 ? 124.314 215.564 184.004 1.00 130.78 ? 335 ALA M C     1 
ATOM   2514 O O     . ALA A 1 330 ? 124.072 214.768 184.917 1.00 130.78 ? 335 ALA M O     1 
ATOM   2515 C CB    . ALA A 1 330 ? 123.983 214.745 181.657 1.00 130.78 ? 335 ALA M CB    1 
ATOM   2516 N N     . PHE A 1 331 ? 125.341 216.408 184.055 1.00 128.69 ? 336 PHE M N     1 
ATOM   2517 C CA    . PHE A 1 331 ? 126.215 216.445 185.220 1.00 128.69 ? 336 PHE M CA    1 
ATOM   2518 C C     . PHE A 1 331 ? 125.453 216.914 186.449 1.00 128.69 ? 336 PHE M C     1 
ATOM   2519 O O     . PHE A 1 331 ? 125.432 216.232 187.479 1.00 128.69 ? 336 PHE M O     1 
ATOM   2520 C CB    . PHE A 1 331 ? 127.407 217.366 184.955 1.00 128.69 ? 336 PHE M CB    1 
ATOM   2521 C CG    . PHE A 1 331 ? 128.488 216.747 184.114 1.00 128.69 ? 336 PHE M CG    1 
ATOM   2522 C CD1   . PHE A 1 331 ? 128.235 215.642 183.324 1.00 128.69 ? 336 PHE M CD1   1 
ATOM   2523 C CD2   . PHE A 1 331 ? 129.768 217.271 184.128 1.00 128.69 ? 336 PHE M CD2   1 
ATOM   2524 C CE1   . PHE A 1 331 ? 129.234 215.084 182.553 1.00 128.69 ? 336 PHE M CE1   1 
ATOM   2525 C CE2   . PHE A 1 331 ? 130.769 216.715 183.362 1.00 128.69 ? 336 PHE M CE2   1 
ATOM   2526 C CZ    . PHE A 1 331 ? 130.503 215.622 182.575 1.00 128.69 ? 336 PHE M CZ    1 
ATOM   2527 N N     . ASP A 1 332 ? 124.811 218.080 186.351 1.00 129.63 ? 337 ASP M N     1 
ATOM   2528 C CA    . ASP A 1 332 ? 124.093 218.627 187.495 1.00 129.63 ? 337 ASP M CA    1 
ATOM   2529 C C     . ASP A 1 332 ? 122.988 217.695 187.966 1.00 129.63 ? 337 ASP M C     1 
ATOM   2530 O O     . ASP A 1 332 ? 122.664 217.677 189.158 1.00 129.63 ? 337 ASP M O     1 
ATOM   2531 C CB    . ASP A 1 332 ? 123.529 220.008 187.160 1.00 129.63 ? 337 ASP M CB    1 
ATOM   2532 C CG    . ASP A 1 332 ? 124.604 221.080 187.111 1.00 129.63 ? 337 ASP M CG    1 
ATOM   2533 O OD1   . ASP A 1 332 ? 124.851 221.708 188.160 1.00 129.63 ? 337 ASP M OD1   1 
ATOM   2534 O OD2   . ASP A 1 332 ? 125.199 221.300 186.035 1.00 129.63 ? 337 ASP M OD2   1 
ATOM   2535 N N     . VAL A 1 333 ? 122.400 216.906 187.060 1.00 130.26 ? 338 VAL M N     1 
ATOM   2536 C CA    . VAL A 1 333 ? 121.400 215.935 187.500 1.00 130.26 ? 338 VAL M CA    1 
ATOM   2537 C C     . VAL A 1 333 ? 122.015 214.601 187.878 1.00 130.26 ? 338 VAL M C     1 
ATOM   2538 O O     . VAL A 1 333 ? 121.283 213.683 188.270 1.00 130.26 ? 338 VAL M O     1 
ATOM   2539 C CB    . VAL A 1 333 ? 120.304 215.676 186.449 1.00 130.26 ? 338 VAL M CB    1 
ATOM   2540 C CG1   . VAL A 1 333 ? 119.434 216.920 186.273 1.00 130.26 ? 338 VAL M CG1   1 
ATOM   2541 C CG2   . VAL A 1 333 ? 120.901 215.201 185.145 1.00 130.26 ? 338 VAL M CG2   1 
ATOM   2542 N N     . LEU A 1 334 ? 123.327 214.452 187.760 1.00 128.70 ? 339 LEU M N     1 
ATOM   2543 C CA    . LEU A 1 334 ? 123.978 213.270 188.294 1.00 128.70 ? 339 LEU M CA    1 
ATOM   2544 C C     . LEU A 1 334 ? 124.492 213.547 189.703 1.00 128.70 ? 339 LEU M C     1 
ATOM   2545 O O     . LEU A 1 334 ? 124.576 214.691 190.152 1.00 128.70 ? 339 LEU M O     1 
ATOM   2546 C CB    . LEU A 1 334 ? 125.102 212.810 187.369 1.00 128.70 ? 339 LEU M CB    1 
ATOM   2547 C CG    . LEU A 1 334 ? 124.586 211.954 186.210 1.00 128.70 ? 339 LEU M CG    1 
ATOM   2548 C CD1   . LEU A 1 334 ? 125.504 212.042 185.002 1.00 128.70 ? 339 LEU M CD1   1 
ATOM   2549 C CD2   . LEU A 1 334 ? 124.404 210.509 186.659 1.00 128.70 ? 339 LEU M CD2   1 
ATOM   2550 N N     . GLY A 1 335 ? 124.853 212.469 190.400 1.00 127.26 ? 340 GLY M N     1 
ATOM   2551 C CA    . GLY A 1 335 ? 125.068 212.538 191.834 1.00 127.26 ? 340 GLY M CA    1 
ATOM   2552 C C     . GLY A 1 335 ? 126.138 213.514 192.275 1.00 127.26 ? 340 GLY M C     1 
ATOM   2553 O O     . GLY A 1 335 ? 126.202 213.845 193.462 1.00 127.26 ? 340 GLY M O     1 
ATOM   2554 N N     . PHE A 1 336 ? 126.978 213.981 191.360 1.00 125.75 ? 341 PHE M N     1 
ATOM   2555 C CA    . PHE A 1 336 ? 128.168 214.705 191.779 1.00 125.75 ? 341 PHE M CA    1 
ATOM   2556 C C     . PHE A 1 336 ? 127.962 216.215 191.716 1.00 125.75 ? 341 PHE M C     1 
ATOM   2557 O O     . PHE A 1 336 ? 127.204 216.741 190.899 1.00 125.75 ? 341 PHE M O     1 
ATOM   2558 C CB    . PHE A 1 336 ? 129.384 214.292 190.945 1.00 125.75 ? 341 PHE M CB    1 
ATOM   2559 C CG    . PHE A 1 336 ? 129.268 214.585 189.478 1.00 125.75 ? 341 PHE M CG    1 
ATOM   2560 C CD1   . PHE A 1 336 ? 128.392 213.875 188.676 1.00 125.75 ? 341 PHE M CD1   1 
ATOM   2561 C CD2   . PHE A 1 336 ? 130.085 215.537 188.893 1.00 125.75 ? 341 PHE M CD2   1 
ATOM   2562 C CE1   . PHE A 1 336 ? 128.305 214.141 187.336 1.00 125.75 ? 341 PHE M CE1   1 
ATOM   2563 C CE2   . PHE A 1 336 ? 130.005 215.799 187.554 1.00 125.75 ? 341 PHE M CE2   1 
ATOM   2564 C CZ    . PHE A 1 336 ? 129.116 215.096 186.775 1.00 125.75 ? 341 PHE M CZ    1 
ATOM   2565 N N     . THR A 1 337 ? 128.688 216.908 192.589 1.00 123.05 ? 342 THR M N     1 
ATOM   2566 C CA    . THR A 1 337 ? 128.450 218.310 192.885 1.00 123.05 ? 342 THR M CA    1 
ATOM   2567 C C     . THR A 1 337 ? 128.890 219.197 191.726 1.00 123.05 ? 342 THR M C     1 
ATOM   2568 O O     . THR A 1 337 ? 129.382 218.735 190.694 1.00 123.05 ? 342 THR M O     1 
ATOM   2569 C CB    . THR A 1 337 ? 129.194 218.711 194.153 1.00 123.05 ? 342 THR M CB    1 
ATOM   2570 O OG1   . THR A 1 337 ? 130.562 218.990 193.836 1.00 123.05 ? 342 THR M OG1   1 
ATOM   2571 C CG2   . THR A 1 337 ? 129.139 217.578 195.163 1.00 123.05 ? 342 THR M CG2   1 
ATOM   2572 N N     . SER A 1 338 ? 128.712 220.506 191.913 1.00 122.44 ? 343 SER M N     1 
ATOM   2573 C CA    . SER A 1 338 ? 129.152 221.482 190.922 1.00 122.44 ? 343 SER M CA    1 
ATOM   2574 C C     . SER A 1 338 ? 130.654 221.723 190.985 1.00 122.44 ? 343 SER M C     1 
ATOM   2575 O O     . SER A 1 338 ? 131.287 221.915 189.941 1.00 122.44 ? 343 SER M O     1 
ATOM   2576 C CB    . SER A 1 338 ? 128.399 222.801 191.119 1.00 122.44 ? 343 SER M CB    1 
ATOM   2577 O OG    . SER A 1 338 ? 129.054 223.611 192.076 1.00 122.44 ? 343 SER M OG    1 
ATOM   2578 N N     . GLU A 1 339 ? 131.236 221.713 192.191 1.00 121.19 ? 344 GLU M N     1 
ATOM   2579 C CA    . GLU A 1 339 ? 132.686 221.805 192.322 1.00 121.19 ? 344 GLU M CA    1 
ATOM   2580 C C     . GLU A 1 339 ? 133.380 220.709 191.534 1.00 121.19 ? 344 GLU M C     1 
ATOM   2581 O O     . GLU A 1 339 ? 134.461 220.922 190.979 1.00 121.19 ? 344 GLU M O     1 
ATOM   2582 C CB    . GLU A 1 339 ? 133.099 221.692 193.785 1.00 121.19 ? 344 GLU M CB    1 
ATOM   2583 C CG    . GLU A 1 339 ? 134.590 221.830 193.996 1.00 121.19 ? 344 GLU M CG    1 
ATOM   2584 C CD    . GLU A 1 339 ? 135.023 221.491 195.405 1.00 121.19 ? 344 GLU M CD    1 
ATOM   2585 O OE1   . GLU A 1 339 ? 134.175 221.034 196.196 1.00 121.19 ? 344 GLU M OE1   1 
ATOM   2586 O OE2   . GLU A 1 339 ? 136.215 221.685 195.724 1.00 121.19 ? 344 GLU M OE2   1 
ATOM   2587 N N     . GLU A 1 340 ? 132.774 219.527 191.490 1.00 121.57 ? 345 GLU M N     1 
ATOM   2588 C CA    . GLU A 1 340 ? 133.386 218.391 190.820 1.00 121.57 ? 345 GLU M CA    1 
ATOM   2589 C C     . GLU A 1 340 ? 133.376 218.572 189.307 1.00 121.57 ? 345 GLU M C     1 
ATOM   2590 O O     . GLU A 1 340 ? 134.372 218.278 188.636 1.00 121.57 ? 345 GLU M O     1 
ATOM   2591 C CB    . GLU A 1 340 ? 132.663 217.126 191.269 1.00 121.57 ? 345 GLU M CB    1 
ATOM   2592 C CG    . GLU A 1 340 ? 133.188 215.821 190.760 1.00 121.57 ? 345 GLU M CG    1 
ATOM   2593 C CD    . GLU A 1 340 ? 132.636 214.682 191.582 1.00 121.57 ? 345 GLU M CD    1 
ATOM   2594 O OE1   . GLU A 1 340 ? 132.020 214.964 192.630 1.00 121.57 ? 345 GLU M OE1   1 
ATOM   2595 O OE2   . GLU A 1 340 ? 132.769 213.513 191.172 1.00 121.57 ? 345 GLU M OE2   1 
ATOM   2596 N N     . LYS A 1 341 ? 132.277 219.085 188.750 1.00 122.84 ? 346 LYS M N     1 
ATOM   2597 C CA    . LYS A 1 341 ? 132.285 219.462 187.340 1.00 122.84 ? 346 LYS M CA    1 
ATOM   2598 C C     . LYS A 1 341 ? 133.306 220.557 187.080 1.00 122.84 ? 346 LYS M C     1 
ATOM   2599 O O     . LYS A 1 341 ? 133.976 220.563 186.040 1.00 122.84 ? 346 LYS M O     1 
ATOM   2600 C CB    . LYS A 1 341 ? 130.899 219.930 186.904 1.00 122.84 ? 346 LYS M CB    1 
ATOM   2601 C CG    . LYS A 1 341 ? 129.759 219.234 187.611 1.00 122.84 ? 346 LYS M CG    1 
ATOM   2602 C CD    . LYS A 1 341 ? 128.432 219.898 187.304 1.00 122.84 ? 346 LYS M CD    1 
ATOM   2603 C CE    . LYS A 1 341 ? 127.399 219.533 188.350 1.00 122.84 ? 346 LYS M CE    1 
ATOM   2604 N NZ    . LYS A 1 341 ? 127.414 218.080 188.665 1.00 122.84 ? 346 LYS M NZ    1 
ATOM   2605 N N     . ASN A 1 342 ? 133.427 221.500 188.014 1.00 119.65 ? 347 ASN M N     1 
ATOM   2606 C CA    . ASN A 1 342 ? 134.406 222.569 187.869 1.00 119.65 ? 347 ASN M CA    1 
ATOM   2607 C C     . ASN A 1 342 ? 135.819 222.008 187.800 1.00 119.65 ? 347 ASN M C     1 
ATOM   2608 O O     . ASN A 1 342 ? 136.624 222.416 186.953 1.00 119.65 ? 347 ASN M O     1 
ATOM   2609 C CB    . ASN A 1 342 ? 134.270 223.543 189.035 1.00 119.65 ? 347 ASN M CB    1 
ATOM   2610 C CG    . ASN A 1 342 ? 135.157 224.743 188.886 1.00 119.65 ? 347 ASN M CG    1 
ATOM   2611 O OD1   . ASN A 1 342 ? 135.452 225.163 187.772 1.00 119.65 ? 347 ASN M OD1   1 
ATOM   2612 N ND2   . ASN A 1 342 ? 135.602 225.299 190.005 1.00 119.65 ? 347 ASN M ND2   1 
ATOM   2613 N N     . SER A 1 343 ? 136.126 221.051 188.675 1.00 117.95 ? 348 SER M N     1 
ATOM   2614 C CA    . SER A 1 343 ? 137.441 220.426 188.668 1.00 117.95 ? 348 SER M CA    1 
ATOM   2615 C C     . SER A 1 343 ? 137.660 219.629 187.392 1.00 117.95 ? 348 SER M C     1 
ATOM   2616 O O     . SER A 1 343 ? 138.761 219.626 186.839 1.00 117.95 ? 348 SER M O     1 
ATOM   2617 C CB    . SER A 1 343 ? 137.608 219.531 189.892 1.00 117.95 ? 348 SER M CB    1 
ATOM   2618 O OG    . SER A 1 343 ? 137.166 218.216 189.612 1.00 117.95 ? 348 SER M OG    1 
ATOM   2619 N N     . MET A 1 344 ? 136.630 218.932 186.916 1.00 118.47 ? 349 MET M N     1 
ATOM   2620 C CA    . MET A 1 344 ? 136.747 218.204 185.657 1.00 118.47 ? 349 MET M CA    1 
ATOM   2621 C C     . MET A 1 344 ? 137.128 219.145 184.521 1.00 118.47 ? 349 MET M C     1 
ATOM   2622 O O     . MET A 1 344 ? 138.074 218.888 183.761 1.00 118.47 ? 349 MET M O     1 
ATOM   2623 C CB    . MET A 1 344 ? 135.429 217.498 185.348 1.00 118.47 ? 349 MET M CB    1 
ATOM   2624 C CG    . MET A 1 344 ? 135.517 216.461 184.260 1.00 118.47 ? 349 MET M CG    1 
ATOM   2625 S SD    . MET A 1 344 ? 134.383 215.090 184.548 1.00 118.47 ? 349 MET M SD    1 
ATOM   2626 C CE    . MET A 1 344 ? 135.143 214.316 185.970 1.00 118.47 ? 349 MET M CE    1 
ATOM   2627 N N     . TYR A 1 345 ? 136.396 220.251 184.401 1.00 120.93 ? 350 TYR M N     1 
ATOM   2628 C CA    . TYR A 1 345 ? 136.663 221.202 183.330 1.00 120.93 ? 350 TYR M CA    1 
ATOM   2629 C C     . TYR A 1 345 ? 138.060 221.783 183.456 1.00 120.93 ? 350 TYR M C     1 
ATOM   2630 O O     . TYR A 1 345 ? 138.793 221.887 182.462 1.00 120.93 ? 350 TYR M O     1 
ATOM   2631 C CB    . TYR A 1 345 ? 135.614 222.313 183.345 1.00 120.93 ? 350 TYR M CB    1 
ATOM   2632 C CG    . TYR A 1 345 ? 134.192 221.807 183.296 1.00 120.93 ? 350 TYR M CG    1 
ATOM   2633 C CD1   . TYR A 1 345 ? 133.161 222.514 183.899 1.00 120.93 ? 350 TYR M CD1   1 
ATOM   2634 C CD2   . TYR A 1 345 ? 133.879 220.626 182.642 1.00 120.93 ? 350 TYR M CD2   1 
ATOM   2635 C CE1   . TYR A 1 345 ? 131.862 222.052 183.859 1.00 120.93 ? 350 TYR M CE1   1 
ATOM   2636 C CE2   . TYR A 1 345 ? 132.586 220.158 182.595 1.00 120.93 ? 350 TYR M CE2   1 
ATOM   2637 C CZ    . TYR A 1 345 ? 131.581 220.873 183.203 1.00 120.93 ? 350 TYR M CZ    1 
ATOM   2638 O OH    . TYR A 1 345 ? 130.288 220.401 183.154 1.00 120.93 ? 350 TYR M OH    1 
ATOM   2639 N N     . LYS A 1 346 ? 138.463 222.145 184.673 1.00 116.24 ? 351 LYS M N     1 
ATOM   2640 C CA    . LYS A 1 346 ? 139.778 222.750 184.827 1.00 116.24 ? 351 LYS M CA    1 
ATOM   2641 C C     . LYS A 1 346 ? 140.884 221.740 184.554 1.00 116.24 ? 351 LYS M C     1 
ATOM   2642 O O     . LYS A 1 346 ? 141.909 222.085 183.961 1.00 116.24 ? 351 LYS M O     1 
ATOM   2643 C CB    . LYS A 1 346 ? 139.913 223.386 186.211 1.00 116.24 ? 351 LYS M CB    1 
ATOM   2644 C CG    . LYS A 1 346 ? 139.911 222.440 187.371 1.00 116.24 ? 351 LYS M CG    1 
ATOM   2645 C CD    . LYS A 1 346 ? 140.480 223.101 188.614 1.00 116.24 ? 351 LYS M CD    1 
ATOM   2646 C CE    . LYS A 1 346 ? 139.698 224.336 188.987 1.00 116.24 ? 351 LYS M CE    1 
ATOM   2647 N NZ    . LYS A 1 346 ? 138.324 223.975 189.392 1.00 116.24 ? 351 LYS M NZ    1 
ATOM   2648 N N     . LEU A 1 347 ? 140.682 220.481 184.935 1.00 113.89 ? 352 LEU M N     1 
ATOM   2649 C CA    . LEU A 1 347 ? 141.674 219.454 184.648 1.00 113.89 ? 352 LEU M CA    1 
ATOM   2650 C C     . LEU A 1 347 ? 141.853 219.275 183.149 1.00 113.89 ? 352 LEU M C     1 
ATOM   2651 O O     . LEU A 1 347 ? 142.983 219.148 182.657 1.00 113.89 ? 352 LEU M O     1 
ATOM   2652 C CB    . LEU A 1 347 ? 141.253 218.139 185.299 1.00 113.89 ? 352 LEU M CB    1 
ATOM   2653 C CG    . LEU A 1 347 ? 142.375 217.279 185.862 1.00 113.89 ? 352 LEU M CG    1 
ATOM   2654 C CD1   . LEU A 1 347 ? 143.248 218.119 186.773 1.00 113.89 ? 352 LEU M CD1   1 
ATOM   2655 C CD2   . LEU A 1 347 ? 141.790 216.104 186.618 1.00 113.89 ? 352 LEU M CD2   1 
ATOM   2656 N N     . THR A 1 348 ? 140.745 219.255 182.406 1.00 113.95 ? 353 THR M N     1 
ATOM   2657 C CA    . THR A 1 348 ? 140.846 219.171 180.954 1.00 113.95 ? 353 THR M CA    1 
ATOM   2658 C C     . THR A 1 348 ? 141.584 220.377 180.388 1.00 113.95 ? 353 THR M C     1 
ATOM   2659 O O     . THR A 1 348 ? 142.406 220.243 179.472 1.00 113.95 ? 353 THR M O     1 
ATOM   2660 C CB    . THR A 1 348 ? 139.454 219.050 180.344 1.00 113.95 ? 353 THR M CB    1 
ATOM   2661 O OG1   . THR A 1 348 ? 138.863 217.818 180.767 1.00 113.95 ? 353 THR M OG1   1 
ATOM   2662 C CG2   . THR A 1 348 ? 139.531 219.066 178.837 1.00 113.95 ? 353 THR M CG2   1 
ATOM   2663 N N     . GLY A 1 349 ? 141.328 221.562 180.941 1.00 113.92 ? 354 GLY M N     1 
ATOM   2664 C CA    . GLY A 1 349 ? 142.077 222.734 180.518 1.00 113.92 ? 354 GLY M CA    1 
ATOM   2665 C C     . GLY A 1 349 ? 143.560 222.644 180.829 1.00 113.92 ? 354 GLY M C     1 
ATOM   2666 O O     . GLY A 1 349 ? 144.389 223.171 180.085 1.00 113.92 ? 354 GLY M O     1 
ATOM   2667 N N     . ALA A 1 350 ? 143.916 221.978 181.924 1.00 111.96 ? 355 ALA M N     1 
ATOM   2668 C CA    . ALA A 1 350 ? 145.326 221.777 182.247 1.00 111.96 ? 355 ALA M CA    1 
ATOM   2669 C C     . ALA A 1 350 ? 145.982 220.836 181.246 1.00 111.96 ? 355 ALA M C     1 
ATOM   2670 O O     . ALA A 1 350 ? 147.112 221.067 180.798 1.00 111.96 ? 355 ALA M O     1 
ATOM   2671 C CB    . ALA A 1 350 ? 145.462 221.231 183.667 1.00 111.96 ? 355 ALA M CB    1 
ATOM   2672 N N     . ILE A 1 351 ? 145.294 219.742 180.918 1.00 110.80 ? 356 ILE M N     1 
ATOM   2673 C CA    . ILE A 1 351 ? 145.761 218.860 179.851 1.00 110.80 ? 356 ILE M CA    1 
ATOM   2674 C C     . ILE A 1 351 ? 145.986 219.659 178.579 1.00 110.80 ? 356 ILE M C     1 
ATOM   2675 O O     . ILE A 1 351 ? 146.960 219.443 177.850 1.00 110.80 ? 356 ILE M O     1 
ATOM   2676 C CB    . ILE A 1 351 ? 144.758 217.716 179.623 1.00 110.80 ? 356 ILE M CB    1 
ATOM   2677 C CG1   . ILE A 1 351 ? 144.644 216.859 180.875 1.00 110.80 ? 356 ILE M CG1   1 
ATOM   2678 C CG2   . ILE A 1 351 ? 145.160 216.872 178.428 1.00 110.80 ? 356 ILE M CG2   1 
ATOM   2679 C CD1   . ILE A 1 351 ? 143.819 215.626 180.677 1.00 110.80 ? 356 ILE M CD1   1 
ATOM   2680 N N     . MET A 1 352 ? 145.092 220.602 178.300 1.00 115.11 ? 357 MET M N     1 
ATOM   2681 C CA    . MET A 1 352 ? 145.251 221.435 177.114 1.00 115.11 ? 357 MET M CA    1 
ATOM   2682 C C     . MET A 1 352 ? 146.466 222.348 177.240 1.00 115.11 ? 357 MET M C     1 
ATOM   2683 O O     . MET A 1 352 ? 147.176 222.592 176.258 1.00 115.11 ? 357 MET M O     1 
ATOM   2684 C CB    . MET A 1 352 ? 143.976 222.242 176.884 1.00 115.11 ? 357 MET M CB    1 
ATOM   2685 C CG    . MET A 1 352 ? 143.622 222.463 175.435 1.00 115.11 ? 357 MET M CG    1 
ATOM   2686 S SD    . MET A 1 352 ? 141.954 223.123 175.293 1.00 115.11 ? 357 MET M SD    1 
ATOM   2687 C CE    . MET A 1 352 ? 142.257 224.868 175.513 1.00 115.11 ? 357 MET M CE    1 
ATOM   2688 N N     . HIS A 1 353 ? 146.724 222.857 178.442 1.00 112.28 ? 358 HIS M N     1 
ATOM   2689 C CA    . HIS A 1 353 ? 147.880 223.715 178.664 1.00 112.28 ? 358 HIS M CA    1 
ATOM   2690 C C     . HIS A 1 353 ? 149.205 222.971 178.632 1.00 112.28 ? 358 HIS M C     1 
ATOM   2691 O O     . HIS A 1 353 ? 150.247 223.616 178.498 1.00 112.28 ? 358 HIS M O     1 
ATOM   2692 C CB    . HIS A 1 353 ? 147.766 224.432 180.003 1.00 112.28 ? 358 HIS M CB    1 
ATOM   2693 C CG    . HIS A 1 353 ? 146.913 225.658 179.967 1.00 112.28 ? 358 HIS M CG    1 
ATOM   2694 N ND1   . HIS A 1 353 ? 145.696 225.741 180.609 1.00 112.28 ? 358 HIS M ND1   1 
ATOM   2695 C CD2   . HIS A 1 353 ? 147.109 226.858 179.373 1.00 112.28 ? 358 HIS M CD2   1 
ATOM   2696 C CE1   . HIS A 1 353 ? 145.180 226.940 180.411 1.00 112.28 ? 358 HIS M CE1   1 
ATOM   2697 N NE2   . HIS A 1 353 ? 146.018 227.637 179.665 1.00 112.28 ? 358 HIS M NE2   1 
ATOM   2698 N N     . PHE A 1 354 ? 149.203 221.648 178.789 1.00 109.45 ? 359 PHE M N     1 
ATOM   2699 C CA    . PHE A 1 354 ? 150.472 220.926 178.722 1.00 109.45 ? 359 PHE M CA    1 
ATOM   2700 C C     . PHE A 1 354 ? 151.150 221.060 177.365 1.00 109.45 ? 359 PHE M C     1 
ATOM   2701 O O     . PHE A 1 354 ? 152.382 221.074 177.294 1.00 109.45 ? 359 PHE M O     1 
ATOM   2702 C CB    . PHE A 1 354 ? 150.296 219.446 179.045 1.00 109.45 ? 359 PHE M CB    1 
ATOM   2703 C CG    . PHE A 1 354 ? 150.371 219.134 180.499 1.00 109.45 ? 359 PHE M CG    1 
ATOM   2704 C CD1   . PHE A 1 354 ? 151.592 219.152 181.145 1.00 109.45 ? 359 PHE M CD1   1 
ATOM   2705 C CD2   . PHE A 1 354 ? 149.248 218.777 181.214 1.00 109.45 ? 359 PHE M CD2   1 
ATOM   2706 C CE1   . PHE A 1 354 ? 151.687 218.860 182.474 1.00 109.45 ? 359 PHE M CE1   1 
ATOM   2707 C CE2   . PHE A 1 354 ? 149.338 218.479 182.551 1.00 109.45 ? 359 PHE M CE2   1 
ATOM   2708 C CZ    . PHE A 1 354 ? 150.563 218.521 183.182 1.00 109.45 ? 359 PHE M CZ    1 
ATOM   2709 N N     . GLY A 1 355 ? 150.381 221.173 176.284 1.00 109.87 ? 360 GLY M N     1 
ATOM   2710 C CA    . GLY A 1 355 ? 150.960 221.049 174.959 1.00 109.87 ? 360 GLY M CA    1 
ATOM   2711 C C     . GLY A 1 355 ? 151.885 222.175 174.550 1.00 109.87 ? 360 GLY M C     1 
ATOM   2712 O O     . GLY A 1 355 ? 152.761 221.961 173.707 1.00 109.87 ? 360 GLY M O     1 
ATOM   2713 N N     . ASN A 1 356 ? 151.711 223.367 175.111 1.00 110.12 ? 361 ASN M N     1 
ATOM   2714 C CA    . ASN A 1 356 ? 152.456 224.527 174.643 1.00 110.12 ? 361 ASN M CA    1 
ATOM   2715 C C     . ASN A 1 356 ? 153.781 224.725 175.364 1.00 110.12 ? 361 ASN M C     1 
ATOM   2716 O O     . ASN A 1 356 ? 154.471 225.712 175.091 1.00 110.12 ? 361 ASN M O     1 
ATOM   2717 C CB    . ASN A 1 356 ? 151.602 225.792 174.770 1.00 110.12 ? 361 ASN M CB    1 
ATOM   2718 C CG    . ASN A 1 356 ? 151.190 226.076 176.196 1.00 110.12 ? 361 ASN M CG    1 
ATOM   2719 O OD1   . ASN A 1 356 ? 151.566 225.356 177.114 1.00 110.12 ? 361 ASN M OD1   1 
ATOM   2720 N ND2   . ASN A 1 356 ? 150.415 227.136 176.390 1.00 110.12 ? 361 ASN M ND2   1 
ATOM   2721 N N     . MET A 1 357 ? 154.144 223.829 176.278 1.00 107.81 ? 362 MET M N     1 
ATOM   2722 C CA    . MET A 1 357 ? 155.426 223.923 176.964 1.00 107.81 ? 362 MET M CA    1 
ATOM   2723 C C     . MET A 1 357 ? 156.577 223.917 175.965 1.00 107.81 ? 362 MET M C     1 
ATOM   2724 O O     . MET A 1 357 ? 156.507 223.294 174.905 1.00 107.81 ? 362 MET M O     1 
ATOM   2725 C CB    . MET A 1 357 ? 155.586 222.763 177.937 1.00 107.81 ? 362 MET M CB    1 
ATOM   2726 C CG    . MET A 1 357 ? 154.530 222.700 179.010 1.00 107.81 ? 362 MET M CG    1 
ATOM   2727 S SD    . MET A 1 357 ? 154.862 223.802 180.389 1.00 107.81 ? 362 MET M SD    1 
ATOM   2728 C CE    . MET A 1 357 ? 153.911 222.989 181.671 1.00 107.81 ? 362 MET M CE    1 
ATOM   2729 N N     . LYS A 1 358 ? 157.648 224.621 176.314 1.00 103.02 ? 363 LYS M N     1 
ATOM   2730 C CA    . LYS A 1 358 ? 158.802 224.758 175.439 1.00 103.02 ? 363 LYS M CA    1 
ATOM   2731 C C     . LYS A 1 358 ? 160.068 224.433 176.210 1.00 103.02 ? 363 LYS M C     1 
ATOM   2732 O O     . LYS A 1 358 ? 160.287 224.969 177.300 1.00 103.02 ? 363 LYS M O     1 
ATOM   2733 C CB    . LYS A 1 358 ? 158.892 226.171 174.862 1.00 103.02 ? 363 LYS M CB    1 
ATOM   2734 C CG    . LYS A 1 358 ? 157.691 226.582 174.030 1.00 103.02 ? 363 LYS M CG    1 
ATOM   2735 C CD    . LYS A 1 358 ? 157.802 228.032 173.604 1.00 103.02 ? 363 LYS M CD    1 
ATOM   2736 C CE    . LYS A 1 358 ? 156.548 228.501 172.904 1.00 103.02 ? 363 LYS M CE    1 
ATOM   2737 N NZ    . LYS A 1 358 ? 156.653 229.928 172.497 1.00 103.02 ? 363 LYS M NZ    1 
ATOM   2738 N N     . PHE A 1 359 ? 160.907 223.578 175.635 1.00 94.59  ? 364 PHE M N     1 
ATOM   2739 C CA    . PHE A 1 359 ? 162.153 223.177 176.263 1.00 94.59  ? 364 PHE M CA    1 
ATOM   2740 C C     . PHE A 1 359 ? 163.305 223.360 175.291 1.00 94.59  ? 364 PHE M C     1 
ATOM   2741 O O     . PHE A 1 359 ? 163.150 223.203 174.079 1.00 94.59  ? 364 PHE M O     1 
ATOM   2742 C CB    . PHE A 1 359 ? 162.100 221.729 176.732 1.00 94.59  ? 364 PHE M CB    1 
ATOM   2743 C CG    . PHE A 1 359 ? 161.178 221.507 177.883 1.00 94.59  ? 364 PHE M CG    1 
ATOM   2744 C CD1   . PHE A 1 359 ? 161.515 221.951 179.145 1.00 94.59  ? 364 PHE M CD1   1 
ATOM   2745 C CD2   . PHE A 1 359 ? 159.975 220.852 177.707 1.00 94.59  ? 364 PHE M CD2   1 
ATOM   2746 C CE1   . PHE A 1 359 ? 160.668 221.749 180.208 1.00 94.59  ? 364 PHE M CE1   1 
ATOM   2747 C CE2   . PHE A 1 359 ? 159.125 220.648 178.767 1.00 94.59  ? 364 PHE M CE2   1 
ATOM   2748 C CZ    . PHE A 1 359 ? 159.471 221.096 180.019 1.00 94.59  ? 364 PHE M CZ    1 
ATOM   2749 N N     . LYS A 1 360 ? 164.465 223.696 175.841 1.00 94.75  ? 365 LYS M N     1 
ATOM   2750 C CA    . LYS A 1 360 ? 165.677 223.883 175.065 1.00 94.75  ? 365 LYS M CA    1 
ATOM   2751 C C     . LYS A 1 360 ? 166.809 223.087 175.697 1.00 94.75  ? 365 LYS M C     1 
ATOM   2752 O O     . LYS A 1 360 ? 166.797 222.799 176.895 1.00 94.75  ? 365 LYS M O     1 
ATOM   2753 C CB    . LYS A 1 360 ? 166.057 225.365 174.986 1.00 94.75  ? 365 LYS M CB    1 
ATOM   2754 C CG    . LYS A 1 360 ? 166.263 225.998 176.339 1.00 94.75  ? 365 LYS M CG    1 
ATOM   2755 C CD    . LYS A 1 360 ? 166.394 227.499 176.238 1.00 94.75  ? 365 LYS M CD    1 
ATOM   2756 C CE    . LYS A 1 360 ? 167.784 227.902 175.803 1.00 94.75  ? 365 LYS M CE    1 
ATOM   2757 N NZ    . LYS A 1 360 ? 168.766 227.742 176.909 1.00 94.75  ? 365 LYS M NZ    1 
ATOM   2758 N N     . LEU A 1 361 ? 167.791 222.722 174.879 1.00 94.21  ? 366 LEU M N     1 
ATOM   2759 C CA    . LEU A 1 361 ? 168.989 222.124 175.439 1.00 94.21  ? 366 LEU M CA    1 
ATOM   2760 C C     . LEU A 1 361 ? 169.787 223.182 176.189 1.00 94.21  ? 366 LEU M C     1 
ATOM   2761 O O     . LEU A 1 361 ? 169.642 224.385 175.968 1.00 94.21  ? 366 LEU M O     1 
ATOM   2762 C CB    . LEU A 1 361 ? 169.859 221.491 174.354 1.00 94.21  ? 366 LEU M CB    1 
ATOM   2763 C CG    . LEU A 1 361 ? 169.525 220.087 173.856 1.00 94.21  ? 366 LEU M CG    1 
ATOM   2764 C CD1   . LEU A 1 361 ? 169.478 219.110 175.001 1.00 94.21  ? 366 LEU M CD1   1 
ATOM   2765 C CD2   . LEU A 1 361 ? 168.240 220.071 173.087 1.00 94.21  ? 366 LEU M CD2   1 
ATOM   2766 N N     . LYS A 1 362 ? 170.654 222.724 177.076 1.00 101.30 ? 367 LYS M N     1 
ATOM   2767 C CA    . LYS A 1 362 ? 171.401 223.645 177.912 1.00 101.30 ? 367 LYS M CA    1 
ATOM   2768 C C     . LYS A 1 362 ? 172.575 224.222 177.132 1.00 101.30 ? 367 LYS M C     1 
ATOM   2769 O O     . LYS A 1 362 ? 172.683 224.076 175.913 1.00 101.30 ? 367 LYS M O     1 
ATOM   2770 C CB    . LYS A 1 362 ? 171.869 222.968 179.195 1.00 101.30 ? 367 LYS M CB    1 
ATOM   2771 C CG    . LYS A 1 362 ? 170.790 222.832 180.241 1.00 101.30 ? 367 LYS M CG    1 
ATOM   2772 C CD    . LYS A 1 362 ? 171.388 222.931 181.619 1.00 101.30 ? 367 LYS M CD    1 
ATOM   2773 C CE    . LYS A 1 362 ? 172.247 224.175 181.727 1.00 101.30 ? 367 LYS M CE    1 
ATOM   2774 N NZ    . LYS A 1 362 ? 172.952 224.241 183.031 1.00 101.30 ? 367 LYS M NZ    1 
ATOM   2775 N N     . GLN A 1 363 ? 173.462 224.900 177.851 1.00 121.81 ? 368 GLN M N     1 
ATOM   2776 C CA    . GLN A 1 363 ? 174.552 225.661 177.261 1.00 121.81 ? 368 GLN M CA    1 
ATOM   2777 C C     . GLN A 1 363 ? 175.524 224.771 176.501 1.00 121.81 ? 368 GLN M C     1 
ATOM   2778 O O     . GLN A 1 363 ? 175.605 224.830 175.271 1.00 121.81 ? 368 GLN M O     1 
ATOM   2779 C CB    . GLN A 1 363 ? 175.290 226.421 178.362 1.00 121.81 ? 368 GLN M CB    1 
ATOM   2780 C CG    . GLN A 1 363 ? 176.358 227.386 177.888 1.00 121.81 ? 368 GLN M CG    1 
ATOM   2781 C CD    . GLN A 1 363 ? 175.897 228.261 176.745 1.00 121.81 ? 368 GLN M CD    1 
ATOM   2782 O OE1   . GLN A 1 363 ? 175.799 227.819 175.599 1.00 121.81 ? 368 GLN M OE1   1 
ATOM   2783 N NE2   . GLN A 1 363 ? 175.603 229.520 177.052 1.00 121.81 ? 368 GLN M NE2   1 
ATOM   2784 N N     . ARG A 1 364 ? 176.250 223.929 177.225 1.00 111.04 ? 369 ARG M N     1 
ATOM   2785 C CA    . ARG A 1 364 ? 177.242 223.037 176.638 1.00 111.04 ? 369 ARG M CA    1 
ATOM   2786 C C     . ARG A 1 364 ? 177.043 221.634 177.201 1.00 111.04 ? 369 ARG M C     1 
ATOM   2787 O O     . ARG A 1 364 ? 177.986 220.958 177.612 1.00 111.04 ? 369 ARG M O     1 
ATOM   2788 C CB    . ARG A 1 364 ? 178.653 223.564 176.895 1.00 111.04 ? 369 ARG M CB    1 
ATOM   2789 C CG    . ARG A 1 364 ? 179.714 223.003 175.966 1.00 111.04 ? 369 ARG M CG    1 
ATOM   2790 C CD    . ARG A 1 364 ? 181.042 223.750 176.098 1.00 111.04 ? 369 ARG M CD    1 
ATOM   2791 N NE    . ARG A 1 364 ? 181.322 224.169 177.470 1.00 111.04 ? 369 ARG M NE    1 
ATOM   2792 C CZ    . ARG A 1 364 ? 181.782 223.371 178.428 1.00 111.04 ? 369 ARG M CZ    1 
ATOM   2793 N NH1   . ARG A 1 364 ? 182.015 222.092 178.181 1.00 111.04 ? 369 ARG M NH1   1 
ATOM   2794 N NH2   . ARG A 1 364 ? 182.001 223.853 179.643 1.00 111.04 ? 369 ARG M NH2   1 
ATOM   2795 N N     . GLU A 1 365 ? 175.788 221.193 177.236 1.00 97.20  ? 370 GLU M N     1 
ATOM   2796 C CA    . GLU A 1 365 ? 175.430 219.898 177.792 1.00 97.20  ? 370 GLU M CA    1 
ATOM   2797 C C     . GLU A 1 365 ? 174.271 219.331 176.985 1.00 97.20  ? 370 GLU M C     1 
ATOM   2798 O O     . GLU A 1 365 ? 173.841 219.913 175.988 1.00 97.20  ? 370 GLU M O     1 
ATOM   2799 C CB    . GLU A 1 365 ? 175.073 220.010 179.274 1.00 97.20  ? 370 GLU M CB    1 
ATOM   2800 C CG    . GLU A 1 365 ? 175.314 218.738 180.066 1.00 97.20  ? 370 GLU M CG    1 
ATOM   2801 C CD    . GLU A 1 365 ? 174.418 218.622 181.285 1.00 97.20  ? 370 GLU M CD    1 
ATOM   2802 O OE1   . GLU A 1 365 ? 173.749 219.618 181.627 1.00 97.20  ? 370 GLU M OE1   1 
ATOM   2803 O OE2   . GLU A 1 365 ? 174.384 217.534 181.898 1.00 97.20  ? 370 GLU M OE2   1 
ATOM   2804 N N     . GLU A 1 366 ? 173.779 218.175 177.414 1.00 84.20  ? 371 GLU M N     1 
ATOM   2805 C CA    . GLU A 1 366 ? 172.654 217.512 176.779 1.00 84.20  ? 371 GLU M CA    1 
ATOM   2806 C C     . GLU A 1 366 ? 171.395 217.555 177.632 1.00 84.20  ? 371 GLU M C     1 
ATOM   2807 O O     . GLU A 1 366 ? 170.501 216.727 177.442 1.00 84.20  ? 371 GLU M O     1 
ATOM   2808 C CB    . GLU A 1 366 ? 173.021 216.067 176.455 1.00 84.20  ? 371 GLU M CB    1 
ATOM   2809 C CG    . GLU A 1 366 ? 172.349 215.520 175.213 1.00 84.20  ? 371 GLU M CG    1 
ATOM   2810 C CD    . GLU A 1 366 ? 172.875 214.154 174.812 1.00 84.20  ? 371 GLU M CD    1 
ATOM   2811 O OE1   . GLU A 1 366 ? 174.105 213.940 174.887 1.00 84.20  ? 371 GLU M OE1   1 
ATOM   2812 O OE2   . GLU A 1 366 ? 172.054 213.295 174.420 1.00 84.20  ? 371 GLU M OE2   1 
ATOM   2813 N N     . GLN A 1 367 ? 171.310 218.490 178.571 1.00 86.72  ? 372 GLN M N     1 
ATOM   2814 C CA    . GLN A 1 367 ? 170.179 218.562 179.484 1.00 86.72  ? 372 GLN M CA    1 
ATOM   2815 C C     . GLN A 1 367 ? 169.119 219.531 178.978 1.00 86.72  ? 372 GLN M C     1 
ATOM   2816 O O     . GLN A 1 367 ? 169.425 220.568 178.389 1.00 86.72  ? 372 GLN M O     1 
ATOM   2817 C CB    . GLN A 1 367 ? 170.656 218.988 180.870 1.00 86.72  ? 372 GLN M CB    1 
ATOM   2818 C CG    . GLN A 1 367 ? 169.570 219.144 181.898 1.00 86.72  ? 372 GLN M CG    1 
ATOM   2819 C CD    . GLN A 1 367 ? 168.823 217.865 182.157 1.00 86.72  ? 372 GLN M CD    1 
ATOM   2820 O OE1   . GLN A 1 367 ? 169.352 216.776 181.969 1.00 86.72  ? 372 GLN M OE1   1 
ATOM   2821 N NE2   . GLN A 1 367 ? 167.583 217.988 182.600 1.00 86.72  ? 372 GLN M NE2   1 
ATOM   2822 N N     . ALA A 1 368 ? 167.860 219.190 179.234 1.00 89.30  ? 373 ALA M N     1 
ATOM   2823 C CA    . ALA A 1 368 ? 166.728 220.029 178.870 1.00 89.30  ? 373 ALA M CA    1 
ATOM   2824 C C     . ALA A 1 368 ? 166.435 221.034 179.976 1.00 89.30  ? 373 ALA M C     1 
ATOM   2825 O O     . ALA A 1 368 ? 166.465 220.697 181.161 1.00 89.30  ? 373 ALA M O     1 
ATOM   2826 C CB    . ALA A 1 368 ? 165.482 219.183 178.603 1.00 89.30  ? 373 ALA M CB    1 
ATOM   2827 N N     . GLU A 1 369 ? 166.161 222.271 179.583 1.00 96.93  ? 374 GLU M N     1 
ATOM   2828 C CA    . GLU A 1 369 ? 165.763 223.317 180.508 1.00 96.93  ? 374 GLU M CA    1 
ATOM   2829 C C     . GLU A 1 369 ? 164.659 224.143 179.873 1.00 96.93  ? 374 GLU M C     1 
ATOM   2830 O O     . GLU A 1 369 ? 164.666 224.359 178.656 1.00 96.93  ? 374 GLU M O     1 
ATOM   2831 C CB    . GLU A 1 369 ? 166.936 224.233 180.874 1.00 96.93  ? 374 GLU M CB    1 
ATOM   2832 C CG    . GLU A 1 369 ? 167.684 224.755 179.678 1.00 96.93  ? 374 GLU M CG    1 
ATOM   2833 C CD    . GLU A 1 369 ? 168.613 225.882 180.040 1.00 96.93  ? 374 GLU M CD    1 
ATOM   2834 O OE1   . GLU A 1 369 ? 168.166 226.811 180.744 1.00 96.93  ? 374 GLU M OE1   1 
ATOM   2835 O OE2   . GLU A 1 369 ? 169.792 225.838 179.635 1.00 96.93  ? 374 GLU M OE2   1 
ATOM   2836 N N     . PRO A 1 370 ? 163.702 224.620 180.665 1.00 98.34  ? 375 PRO M N     1 
ATOM   2837 C CA    . PRO A 1 370 ? 162.593 225.385 180.093 1.00 98.34  ? 375 PRO M CA    1 
ATOM   2838 C C     . PRO A 1 370 ? 162.995 226.824 179.830 1.00 98.34  ? 375 PRO M C     1 
ATOM   2839 O O     . PRO A 1 370 ? 163.651 227.466 180.653 1.00 98.34  ? 375 PRO M O     1 
ATOM   2840 C CB    . PRO A 1 370 ? 161.512 225.309 181.180 1.00 98.34  ? 375 PRO M CB    1 
ATOM   2841 C CG    . PRO A 1 370 ? 162.054 224.385 182.241 1.00 98.34  ? 375 PRO M CG    1 
ATOM   2842 C CD    . PRO A 1 370 ? 163.530 224.428 182.110 1.00 98.34  ? 375 PRO M CD    1 
ATOM   2843 N N     . ASP A 1 371 ? 162.592 227.331 178.667 1.00 103.88 ? 376 ASP M N     1 
ATOM   2844 C CA    . ASP A 1 371 ? 162.739 228.747 178.348 1.00 103.88 ? 376 ASP M CA    1 
ATOM   2845 C C     . ASP A 1 371 ? 161.457 229.521 178.615 1.00 103.88 ? 376 ASP M C     1 
ATOM   2846 O O     . ASP A 1 371 ? 161.490 230.580 179.244 1.00 103.88 ? 376 ASP M O     1 
ATOM   2847 C CB    . ASP A 1 371 ? 163.176 228.932 176.888 1.00 103.88 ? 376 ASP M CB    1 
ATOM   2848 C CG    . ASP A 1 371 ? 162.165 228.389 175.901 1.00 103.88 ? 376 ASP M CG    1 
ATOM   2849 O OD1   . ASP A 1 371 ? 162.060 228.944 174.788 1.00 103.88 ? 376 ASP M OD1   1 
ATOM   2850 O OD2   . ASP A 1 371 ? 161.468 227.410 176.241 1.00 103.88 ? 376 ASP M OD2   1 
ATOM   2851 N N     . GLY A 1 372 ? 160.321 229.000 178.158 1.00 109.65 ? 377 GLY M N     1 
ATOM   2852 C CA    . GLY A 1 372 ? 159.037 229.597 178.464 1.00 109.65 ? 377 GLY M CA    1 
ATOM   2853 C C     . GLY A 1 372 ? 158.492 229.030 179.763 1.00 109.65 ? 377 GLY M C     1 
ATOM   2854 O O     . GLY A 1 372 ? 158.465 227.819 179.966 1.00 109.65 ? 377 GLY M O     1 
ATOM   2855 N N     . THR A 1 373 ? 158.060 229.927 180.643 1.00 110.75 ? 378 THR M N     1 
ATOM   2856 C CA    . THR A 1 373 ? 157.608 229.537 181.966 1.00 110.75 ? 378 THR M CA    1 
ATOM   2857 C C     . THR A 1 373 ? 156.172 229.929 182.262 1.00 110.75 ? 378 THR M C     1 
ATOM   2858 O O     . THR A 1 373 ? 155.644 229.519 183.298 1.00 110.75 ? 378 THR M O     1 
ATOM   2859 C CB    . THR A 1 373 ? 158.516 230.151 183.040 1.00 110.75 ? 378 THR M CB    1 
ATOM   2860 O OG1   . THR A 1 373 ? 158.240 231.552 183.151 1.00 110.75 ? 378 THR M OG1   1 
ATOM   2861 C CG2   . THR A 1 373 ? 159.973 229.964 182.667 1.00 110.75 ? 378 THR M CG2   1 
ATOM   2862 N N     . GLU A 1 374 ? 155.527 230.696 181.387 1.00 112.32 ? 379 GLU M N     1 
ATOM   2863 C CA    . GLU A 1 374 ? 154.221 231.264 181.700 1.00 112.32 ? 379 GLU M CA    1 
ATOM   2864 C C     . GLU A 1 374 ? 153.138 230.194 181.705 1.00 112.32 ? 379 GLU M C     1 
ATOM   2865 O O     . GLU A 1 374 ? 152.342 230.099 182.649 1.00 112.32 ? 379 GLU M O     1 
ATOM   2866 C CB    . GLU A 1 374 ? 153.893 232.364 180.693 1.00 112.32 ? 379 GLU M CB    1 
ATOM   2867 C CG    . GLU A 1 374 ? 155.041 233.336 180.438 1.00 112.32 ? 379 GLU M CG    1 
ATOM   2868 C CD    . GLU A 1 374 ? 156.049 232.821 179.418 1.00 112.32 ? 379 GLU M CD    1 
ATOM   2869 O OE1   . GLU A 1 374 ? 156.816 233.642 178.872 1.00 112.32 ? 379 GLU M OE1   1 
ATOM   2870 O OE2   . GLU A 1 374 ? 156.078 231.597 179.168 1.00 112.32 ? 379 GLU M OE2   1 
ATOM   2871 N N     . GLU A 1 375 ? 153.078 229.393 180.644 1.00 111.20 ? 380 GLU M N     1 
ATOM   2872 C CA    . GLU A 1 375 ? 152.149 228.271 180.623 1.00 111.20 ? 380 GLU M CA    1 
ATOM   2873 C C     . GLU A 1 375 ? 152.462 227.267 181.719 1.00 111.20 ? 380 GLU M C     1 
ATOM   2874 O O     . GLU A 1 375 ? 151.549 226.639 182.256 1.00 111.20 ? 380 GLU M O     1 
ATOM   2875 C CB    . GLU A 1 375 ? 152.169 227.607 179.248 1.00 111.20 ? 380 GLU M CB    1 
ATOM   2876 C CG    . GLU A 1 375 ? 153.529 227.110 178.823 1.00 111.20 ? 380 GLU M CG    1 
ATOM   2877 C CD    . GLU A 1 375 ? 154.333 228.192 178.145 1.00 111.20 ? 380 GLU M CD    1 
ATOM   2878 O OE1   . GLU A 1 375 ? 153.962 229.374 178.279 1.00 111.20 ? 380 GLU M OE1   1 
ATOM   2879 O OE2   . GLU A 1 375 ? 155.333 227.866 177.476 1.00 111.20 ? 380 GLU M OE2   1 
ATOM   2880 N N     . ALA A 1 376 ? 153.737 227.124 182.083 1.00 109.58 ? 381 ALA M N     1 
ATOM   2881 C CA    . ALA A 1 376 ? 154.087 226.284 183.222 1.00 109.58 ? 381 ALA M CA    1 
ATOM   2882 C C     . ALA A 1 376 ? 153.458 226.818 184.501 1.00 109.58 ? 381 ALA M C     1 
ATOM   2883 O O     . ALA A 1 376 ? 152.827 226.071 185.258 1.00 109.58 ? 381 ALA M O     1 
ATOM   2884 C CB    . ALA A 1 376 ? 155.605 226.203 183.361 1.00 109.58 ? 381 ALA M CB    1 
ATOM   2885 N N     . ASP A 1 377 ? 153.617 228.119 184.749 1.00 110.03 ? 382 ASP M N     1 
ATOM   2886 C CA    . ASP A 1 377 ? 153.028 228.733 185.933 1.00 110.03 ? 382 ASP M CA    1 
ATOM   2887 C C     . ASP A 1 377 ? 151.517 228.557 185.953 1.00 110.03 ? 382 ASP M C     1 
ATOM   2888 O O     . ASP A 1 377 ? 150.943 228.200 186.986 1.00 110.03 ? 382 ASP M O     1 
ATOM   2889 C CB    . ASP A 1 377 ? 153.389 230.218 185.996 1.00 110.03 ? 382 ASP M CB    1 
ATOM   2890 C CG    . ASP A 1 377 ? 154.888 230.463 186.031 1.00 110.03 ? 382 ASP M CG    1 
ATOM   2891 O OD1   . ASP A 1 377 ? 155.356 231.396 185.346 1.00 110.03 ? 382 ASP M OD1   1 
ATOM   2892 O OD2   . ASP A 1 377 ? 155.601 229.733 186.749 1.00 110.03 ? 382 ASP M OD2   1 
ATOM   2893 N N     . LYS A 1 378 ? 150.852 228.800 184.823 1.00 110.33 ? 383 LYS M N     1 
ATOM   2894 C CA    . LYS A 1 378 ? 149.394 228.745 184.841 1.00 110.33 ? 383 LYS M CA    1 
ATOM   2895 C C     . LYS A 1 378 ? 148.898 227.309 184.961 1.00 110.33 ? 383 LYS M C     1 
ATOM   2896 O O     . LYS A 1 378 ? 147.906 227.046 185.653 1.00 110.33 ? 383 LYS M O     1 
ATOM   2897 C CB    . LYS A 1 378 ? 148.802 229.431 183.607 1.00 110.33 ? 383 LYS M CB    1 
ATOM   2898 C CG    . LYS A 1 378 ? 149.041 228.736 182.290 1.00 110.33 ? 383 LYS M CG    1 
ATOM   2899 C CD    . LYS A 1 378 ? 148.334 229.465 181.157 1.00 110.33 ? 383 LYS M CD    1 
ATOM   2900 C CE    . LYS A 1 378 ? 149.023 230.771 180.818 1.00 110.33 ? 383 LYS M CE    1 
ATOM   2901 N NZ    . LYS A 1 378 ? 148.440 231.388 179.599 1.00 110.33 ? 383 LYS M NZ    1 
ATOM   2902 N N     . SER A 1 379 ? 149.590 226.359 184.332 1.00 108.93 ? 384 SER M N     1 
ATOM   2903 C CA    . SER A 1 379 ? 149.194 224.967 184.470 1.00 108.93 ? 384 SER M CA    1 
ATOM   2904 C C     . SER A 1 379 ? 149.402 224.483 185.895 1.00 108.93 ? 384 SER M C     1 
ATOM   2905 O O     . SER A 1 379 ? 148.601 223.699 186.408 1.00 108.93 ? 384 SER M O     1 
ATOM   2906 C CB    . SER A 1 379 ? 149.969 224.096 183.487 1.00 108.93 ? 384 SER M CB    1 
ATOM   2907 O OG    . SER A 1 379 ? 149.315 222.855 183.302 1.00 108.93 ? 384 SER M OG    1 
ATOM   2908 N N     . ALA A 1 380 ? 150.457 224.954 186.562 1.00 107.90 ? 385 ALA M N     1 
ATOM   2909 C CA    . ALA A 1 380 ? 150.649 224.584 187.960 1.00 107.90 ? 385 ALA M CA    1 
ATOM   2910 C C     . ALA A 1 380 ? 149.587 225.215 188.846 1.00 107.90 ? 385 ALA M C     1 
ATOM   2911 O O     . ALA A 1 380 ? 149.052 224.559 189.747 1.00 107.90 ? 385 ALA M O     1 
ATOM   2912 C CB    . ALA A 1 380 ? 152.041 224.993 188.429 1.00 107.90 ? 385 ALA M CB    1 
ATOM   2913 N N     . TYR A 1 381 ? 149.279 226.493 188.612 1.00 110.15 ? 386 TYR M N     1 
ATOM   2914 C CA    . TYR A 1 381 ? 148.238 227.164 189.380 1.00 110.15 ? 386 TYR M CA    1 
ATOM   2915 C C     . TYR A 1 381 ? 146.896 226.479 189.207 1.00 110.15 ? 386 TYR M C     1 
ATOM   2916 O O     . TYR A 1 381 ? 146.062 226.496 190.118 1.00 110.15 ? 386 TYR M O     1 
ATOM   2917 C CB    . TYR A 1 381 ? 148.139 228.626 188.957 1.00 110.15 ? 386 TYR M CB    1 
ATOM   2918 C CG    . TYR A 1 381 ? 146.826 229.284 189.315 1.00 110.15 ? 386 TYR M CG    1 
ATOM   2919 C CD1   . TYR A 1 381 ? 146.566 229.692 190.612 1.00 110.15 ? 386 TYR M CD1   1 
ATOM   2920 C CD2   . TYR A 1 381 ? 145.854 229.509 188.351 1.00 110.15 ? 386 TYR M CD2   1 
ATOM   2921 C CE1   . TYR A 1 381 ? 145.377 230.298 190.940 1.00 110.15 ? 386 TYR M CE1   1 
ATOM   2922 C CE2   . TYR A 1 381 ? 144.665 230.115 188.669 1.00 110.15 ? 386 TYR M CE2   1 
ATOM   2923 C CZ    . TYR A 1 381 ? 144.431 230.509 189.965 1.00 110.15 ? 386 TYR M CZ    1 
ATOM   2924 O OH    . TYR A 1 381 ? 143.242 231.116 190.291 1.00 110.15 ? 386 TYR M OH    1 
ATOM   2925 N N     . LEU A 1 382 ? 146.666 225.884 188.043 1.00 109.14 ? 387 LEU M N     1 
ATOM   2926 C CA    . LEU A 1 382 ? 145.443 225.122 187.848 1.00 109.14 ? 387 LEU M CA    1 
ATOM   2927 C C     . LEU A 1 382 ? 145.524 223.781 188.568 1.00 109.14 ? 387 LEU M C     1 
ATOM   2928 O O     . LEU A 1 382 ? 144.614 223.406 189.314 1.00 109.14 ? 387 LEU M O     1 
ATOM   2929 C CB    . LEU A 1 382 ? 145.197 224.922 186.356 1.00 109.14 ? 387 LEU M CB    1 
ATOM   2930 C CG    . LEU A 1 382 ? 143.803 224.462 185.940 1.00 109.14 ? 387 LEU M CG    1 
ATOM   2931 C CD1   . LEU A 1 382 ? 143.589 224.793 184.480 1.00 109.14 ? 387 LEU M CD1   1 
ATOM   2932 C CD2   . LEU A 1 382 ? 143.584 222.984 186.213 1.00 109.14 ? 387 LEU M CD2   1 
ATOM   2933 N N     . MET A 1 383 ? 146.610 223.041 188.347 1.00 107.35 ? 388 MET M N     1 
ATOM   2934 C CA    . MET A 1 383 ? 146.713 221.670 188.822 1.00 107.35 ? 388 MET M CA    1 
ATOM   2935 C C     . MET A 1 383 ? 146.830 221.577 190.332 1.00 107.35 ? 388 MET M C     1 
ATOM   2936 O O     . MET A 1 383 ? 146.537 220.519 190.897 1.00 107.35 ? 388 MET M O     1 
ATOM   2937 C CB    . MET A 1 383 ? 147.919 220.993 188.169 1.00 107.35 ? 388 MET M CB    1 
ATOM   2938 C CG    . MET A 1 383 ? 147.743 220.723 186.688 1.00 107.35 ? 388 MET M CG    1 
ATOM   2939 S SD    . MET A 1 383 ? 146.653 219.326 186.385 1.00 107.35 ? 388 MET M SD    1 
ATOM   2940 C CE    . MET A 1 383 ? 147.802 218.177 185.648 1.00 107.35 ? 388 MET M CE    1 
ATOM   2941 N N     . GLY A 1 384 ? 147.235 222.653 190.997 1.00 102.84 ? 389 GLY M N     1 
ATOM   2942 C CA    . GLY A 1 384 ? 147.450 222.588 192.426 1.00 102.84 ? 389 GLY M CA    1 
ATOM   2943 C C     . GLY A 1 384 ? 148.840 222.155 192.818 1.00 102.84 ? 389 GLY M C     1 
ATOM   2944 O O     . GLY A 1 384 ? 149.013 221.530 193.867 1.00 102.84 ? 389 GLY M O     1 
ATOM   2945 N N     . LEU A 1 385 ? 149.835 222.456 191.997 1.00 99.88  ? 390 LEU M N     1 
ATOM   2946 C CA    . LEU A 1 385 ? 151.233 222.205 192.297 1.00 99.88  ? 390 LEU M CA    1 
ATOM   2947 C C     . LEU A 1 385 ? 152.009 223.508 192.195 1.00 99.88  ? 390 LEU M C     1 
ATOM   2948 O O     . LEU A 1 385 ? 151.471 224.547 191.812 1.00 99.88  ? 390 LEU M O     1 
ATOM   2949 C CB    . LEU A 1 385 ? 151.820 221.167 191.342 1.00 99.88  ? 390 LEU M CB    1 
ATOM   2950 C CG    . LEU A 1 385 ? 150.963 219.947 191.037 1.00 99.88  ? 390 LEU M CG    1 
ATOM   2951 C CD1   . LEU A 1 385 ? 151.654 219.121 189.991 1.00 99.88  ? 390 LEU M CD1   1 
ATOM   2952 C CD2   . LEU A 1 385 ? 150.728 219.134 192.288 1.00 99.88  ? 390 LEU M CD2   1 
ATOM   2953 N N     . ASN A 1 386 ? 153.294 223.442 192.523 1.00 96.45  ? 391 ASN M N     1 
ATOM   2954 C CA    . ASN A 1 386 ? 154.192 224.574 192.360 1.00 96.45  ? 391 ASN M CA    1 
ATOM   2955 C C     . ASN A 1 386 ? 154.823 224.518 190.977 1.00 96.45  ? 391 ASN M C     1 
ATOM   2956 O O     . ASN A 1 386 ? 155.150 223.441 190.475 1.00 96.45  ? 391 ASN M O     1 
ATOM   2957 C CB    . ASN A 1 386 ? 155.276 224.578 193.436 1.00 96.45  ? 391 ASN M CB    1 
ATOM   2958 C CG    . ASN A 1 386 ? 156.219 225.752 193.303 1.00 96.45  ? 391 ASN M CG    1 
ATOM   2959 O OD1   . ASN A 1 386 ? 155.946 226.700 192.571 1.00 96.45  ? 391 ASN M OD1   1 
ATOM   2960 N ND2   . ASN A 1 386 ? 157.333 225.701 194.018 1.00 96.45  ? 391 ASN M ND2   1 
ATOM   2961 N N     . SER A 1 387 ? 154.994 225.688 190.363 1.00 95.63  ? 392 SER M N     1 
ATOM   2962 C CA    . SER A 1 387 ? 155.492 225.730 188.994 1.00 95.63  ? 392 SER M CA    1 
ATOM   2963 C C     . SER A 1 387 ? 156.960 225.336 188.927 1.00 95.63  ? 392 SER M C     1 
ATOM   2964 O O     . SER A 1 387 ? 157.351 224.497 188.107 1.00 95.63  ? 392 SER M O     1 
ATOM   2965 C CB    . SER A 1 387 ? 155.284 227.121 188.408 1.00 95.63  ? 392 SER M CB    1 
ATOM   2966 O OG    . SER A 1 387 ? 156.380 227.959 188.719 1.00 95.63  ? 392 SER M OG    1 
ATOM   2967 N N     . ALA A 1 388 ? 157.792 225.947 189.770 1.00 92.28  ? 393 ALA M N     1 
ATOM   2968 C CA    . ALA A 1 388 ? 159.198 225.570 189.812 1.00 92.28  ? 393 ALA M CA    1 
ATOM   2969 C C     . ALA A 1 388 ? 159.353 224.096 190.145 1.00 92.28  ? 393 ALA M C     1 
ATOM   2970 O O     . ALA A 1 388 ? 160.210 223.410 189.579 1.00 92.28  ? 393 ALA M O     1 
ATOM   2971 C CB    . ALA A 1 388 ? 159.940 226.432 190.829 1.00 92.28  ? 393 ALA M CB    1 
ATOM   2972 N N     . ASP A 1 389 ? 158.507 223.585 191.039 1.00 91.86  ? 394 ASP M N     1 
ATOM   2973 C CA    . ASP A 1 389 ? 158.606 222.189 191.444 1.00 91.86  ? 394 ASP M CA    1 
ATOM   2974 C C     . ASP A 1 389 ? 158.219 221.255 190.303 1.00 91.86  ? 394 ASP M C     1 
ATOM   2975 O O     . ASP A 1 389 ? 158.865 220.225 190.096 1.00 91.86  ? 394 ASP M O     1 
ATOM   2976 C CB    . ASP A 1 389 ? 157.734 221.954 192.678 1.00 91.86  ? 394 ASP M CB    1 
ATOM   2977 C CG    . ASP A 1 389 ? 157.973 220.604 193.329 1.00 91.86  ? 394 ASP M CG    1 
ATOM   2978 O OD1   . ASP A 1 389 ? 158.108 220.573 194.569 1.00 91.86  ? 394 ASP M OD1   1 
ATOM   2979 O OD2   . ASP A 1 389 ? 158.003 219.574 192.625 1.00 91.86  ? 394 ASP M OD2   1 
ATOM   2980 N N     . LEU A 1 390 ? 157.185 221.600 189.538 1.00 89.63  ? 395 LEU M N     1 
ATOM   2981 C CA    . LEU A 1 390 ? 156.812 220.757 188.407 1.00 89.63  ? 395 LEU M CA    1 
ATOM   2982 C C     . LEU A 1 390 ? 157.870 220.811 187.314 1.00 89.63  ? 395 LEU M C     1 
ATOM   2983 O O     . LEU A 1 390 ? 158.179 219.791 186.688 1.00 89.63  ? 395 LEU M O     1 
ATOM   2984 C CB    . LEU A 1 390 ? 155.448 221.178 187.869 1.00 89.63  ? 395 LEU M CB    1 
ATOM   2985 C CG    . LEU A 1 390 ? 154.574 220.141 187.158 1.00 89.63  ? 395 LEU M CG    1 
ATOM   2986 C CD1   . LEU A 1 390 ? 153.187 220.695 186.961 1.00 89.63  ? 395 LEU M CD1   1 
ATOM   2987 C CD2   . LEU A 1 390 ? 155.138 219.734 185.820 1.00 89.63  ? 395 LEU M CD2   1 
ATOM   2988 N N     . LEU A 1 391 ? 158.444 221.989 187.074 1.00 88.19  ? 396 LEU M N     1 
ATOM   2989 C CA    . LEU A 1 391 ? 159.509 222.093 186.083 1.00 88.19  ? 396 LEU M CA    1 
ATOM   2990 C C     . LEU A 1 391 ? 160.722 221.276 186.497 1.00 88.19  ? 396 LEU M C     1 
ATOM   2991 O O     . LEU A 1 391 ? 161.362 220.626 185.662 1.00 88.19  ? 396 LEU M O     1 
ATOM   2992 C CB    . LEU A 1 391 ? 159.895 223.554 185.882 1.00 88.19  ? 396 LEU M CB    1 
ATOM   2993 C CG    . LEU A 1 391 ? 158.828 224.420 185.224 1.00 88.19  ? 396 LEU M CG    1 
ATOM   2994 C CD1   . LEU A 1 391 ? 159.347 225.824 185.020 1.00 88.19  ? 396 LEU M CD1   1 
ATOM   2995 C CD2   . LEU A 1 391 ? 158.407 223.804 183.910 1.00 88.19  ? 396 LEU M CD2   1 
ATOM   2996 N N     . LYS A 1 392 ? 161.048 221.288 187.787 1.00 85.08  ? 397 LYS M N     1 
ATOM   2997 C CA    . LYS A 1 392 ? 162.158 220.483 188.273 1.00 85.08  ? 397 LYS M CA    1 
ATOM   2998 C C     . LYS A 1 392 ? 161.847 218.998 188.164 1.00 85.08  ? 397 LYS M C     1 
ATOM   2999 O O     . LYS A 1 392 ? 162.724 218.200 187.825 1.00 85.08  ? 397 LYS M O     1 
ATOM   3000 C CB    . LYS A 1 392 ? 162.481 220.871 189.711 1.00 85.08  ? 397 LYS M CB    1 
ATOM   3001 C CG    . LYS A 1 392 ? 163.823 220.390 190.198 1.00 85.08  ? 397 LYS M CG    1 
ATOM   3002 C CD    . LYS A 1 392 ? 164.223 221.111 191.466 1.00 85.08  ? 397 LYS M CD    1 
ATOM   3003 C CE    . LYS A 1 392 ? 165.491 220.535 192.054 1.00 85.08  ? 397 LYS M CE    1 
ATOM   3004 N NZ    . LYS A 1 392 ? 165.251 219.197 192.646 1.00 85.08  ? 397 LYS M NZ    1 
ATOM   3005 N N     . GLY A 1 393 ? 160.601 218.610 188.429 1.00 82.99  ? 398 GLY M N     1 
ATOM   3006 C CA    . GLY A 1 393 ? 160.229 217.214 188.305 1.00 82.99  ? 398 GLY M CA    1 
ATOM   3007 C C     . GLY A 1 393 ? 160.200 216.723 186.874 1.00 82.99  ? 398 GLY M C     1 
ATOM   3008 O O     . GLY A 1 393 ? 160.309 215.521 186.625 1.00 82.99  ? 398 GLY M O     1 
ATOM   3009 N N     . LEU A 1 394 ? 160.025 217.631 185.916 1.00 82.15  ? 399 LEU M N     1 
ATOM   3010 C CA    . LEU A 1 394 ? 160.094 217.211 184.521 1.00 82.15  ? 399 LEU M CA    1 
ATOM   3011 C C     . LEU A 1 394 ? 161.523 217.186 184.004 1.00 82.15  ? 399 LEU M C     1 
ATOM   3012 O O     . LEU A 1 394 ? 161.892 216.283 183.248 1.00 82.15  ? 399 LEU M O     1 
ATOM   3013 C CB    . LEU A 1 394 ? 159.246 218.113 183.633 1.00 82.15  ? 399 LEU M CB    1 
ATOM   3014 C CG    . LEU A 1 394 ? 157.739 217.982 183.772 1.00 82.15  ? 399 LEU M CG    1 
ATOM   3015 C CD1   . LEU A 1 394 ? 157.083 218.958 182.837 1.00 82.15  ? 399 LEU M CD1   1 
ATOM   3016 C CD2   . LEU A 1 394 ? 157.300 216.578 183.462 1.00 82.15  ? 399 LEU M CD2   1 
ATOM   3017 N N     . CYS A 1 395 ? 162.341 218.161 184.378 1.00 80.29  ? 400 CYS M N     1 
ATOM   3018 C CA    . CYS A 1 395 ? 163.694 218.178 183.843 1.00 80.29  ? 400 CYS M CA    1 
ATOM   3019 C C     . CYS A 1 395 ? 164.617 217.193 184.549 1.00 80.29  ? 400 CYS M C     1 
ATOM   3020 O O     . CYS A 1 395 ? 165.575 216.716 183.936 1.00 80.29  ? 400 CYS M O     1 
ATOM   3021 C CB    . CYS A 1 395 ? 164.273 219.586 183.923 1.00 80.29  ? 400 CYS M CB    1 
ATOM   3022 S SG    . CYS A 1 395 ? 163.681 220.688 182.631 1.00 80.29  ? 400 CYS M SG    1 
ATOM   3023 N N     . HIS A 1 396 ? 164.369 216.874 185.818 1.00 74.22  ? 401 HIS M N     1 
ATOM   3024 C CA    . HIS A 1 396 ? 165.289 216.069 186.620 1.00 74.22  ? 401 HIS M CA    1 
ATOM   3025 C C     . HIS A 1 396 ? 164.544 215.030 187.440 1.00 74.22  ? 401 HIS M C     1 
ATOM   3026 O O     . HIS A 1 396 ? 164.394 215.183 188.657 1.00 74.22  ? 401 HIS M O     1 
ATOM   3027 C CB    . HIS A 1 396 ? 166.112 216.952 187.553 1.00 74.22  ? 401 HIS M CB    1 
ATOM   3028 C CG    . HIS A 1 396 ? 166.931 217.981 186.847 1.00 74.22  ? 401 HIS M CG    1 
ATOM   3029 N ND1   . HIS A 1 396 ? 166.420 219.198 186.459 1.00 74.22  ? 401 HIS M ND1   1 
ATOM   3030 C CD2   . HIS A 1 396 ? 168.228 217.977 186.466 1.00 74.22  ? 401 HIS M CD2   1 
ATOM   3031 C CE1   . HIS A 1 396 ? 167.369 219.900 185.868 1.00 74.22  ? 401 HIS M CE1   1 
ATOM   3032 N NE2   . HIS A 1 396 ? 168.475 219.181 185.859 1.00 74.22  ? 401 HIS M NE2   1 
ATOM   3033 N N     . PRO A 1 397 ? 164.098 213.946 186.822 1.00 69.67  ? 402 PRO M N     1 
ATOM   3034 C CA    . PRO A 1 397 ? 163.468 212.878 187.597 1.00 69.67  ? 402 PRO M CA    1 
ATOM   3035 C C     . PRO A 1 397 ? 164.456 212.282 188.578 1.00 69.67  ? 402 PRO M C     1 
ATOM   3036 O O     . PRO A 1 397 ? 165.666 212.324 188.366 1.00 69.67  ? 402 PRO M O     1 
ATOM   3037 C CB    . PRO A 1 397 ? 163.057 211.856 186.534 1.00 69.67  ? 402 PRO M CB    1 
ATOM   3038 C CG    . PRO A 1 397 ? 163.188 212.549 185.247 1.00 69.67  ? 402 PRO M CG    1 
ATOM   3039 C CD    . PRO A 1 397 ? 164.216 213.597 185.405 1.00 69.67  ? 402 PRO M CD    1 
ATOM   3040 N N     . ARG A 1 398 ? 163.938 211.756 189.677 1.00 66.06  ? 403 ARG M N     1 
ATOM   3041 C CA    . ARG A 1 398 ? 164.747 211.038 190.647 1.00 66.06  ? 403 ARG M CA    1 
ATOM   3042 C C     . ARG A 1 398 ? 164.278 209.598 190.712 1.00 66.06  ? 403 ARG M C     1 
ATOM   3043 O O     . ARG A 1 398 ? 163.081 209.339 190.852 1.00 66.06  ? 403 ARG M O     1 
ATOM   3044 C CB    . ARG A 1 398 ? 164.669 211.693 192.022 1.00 66.06  ? 403 ARG M CB    1 
ATOM   3045 C CG    . ARG A 1 398 ? 165.481 212.966 192.104 1.00 66.06  ? 403 ARG M CG    1 
ATOM   3046 C CD    . ARG A 1 398 ? 165.080 213.828 193.274 1.00 66.06  ? 403 ARG M CD    1 
ATOM   3047 N NE    . ARG A 1 398 ? 165.653 213.376 194.535 1.00 66.06  ? 403 ARG M NE    1 
ATOM   3048 C CZ    . ARG A 1 398 ? 165.016 212.610 195.412 1.00 66.06  ? 403 ARG M CZ    1 
ATOM   3049 N NH1   . ARG A 1 398 ? 163.781 212.200 195.157 1.00 66.06  ? 403 ARG M NH1   1 
ATOM   3050 N NH2   . ARG A 1 398 ? 165.613 212.258 196.543 1.00 66.06  ? 403 ARG M NH2   1 
ATOM   3051 N N     . VAL A 1 399 ? 165.220 208.670 190.616 1.00 60.33  ? 404 VAL M N     1 
ATOM   3052 C CA    . VAL A 1 399 ? 164.927 207.246 190.590 1.00 60.33  ? 404 VAL M CA    1 
ATOM   3053 C C     . VAL A 1 399 ? 165.597 206.593 191.792 1.00 60.33  ? 404 VAL M C     1 
ATOM   3054 O O     . VAL A 1 399 ? 166.546 207.135 192.364 1.00 60.33  ? 404 VAL M O     1 
ATOM   3055 C CB    . VAL A 1 399 ? 165.396 206.625 189.259 1.00 60.33  ? 404 VAL M CB    1 
ATOM   3056 C CG1   . VAL A 1 399 ? 166.873 206.860 189.068 1.00 60.33  ? 404 VAL M CG1   1 
ATOM   3057 C CG2   . VAL A 1 399 ? 165.048 205.154 189.176 1.00 60.33  ? 404 VAL M CG2   1 
ATOM   3058 N N     . LYS A 1 400 ? 165.081 205.435 192.192 1.00 58.68  ? 405 LYS M N     1 
ATOM   3059 C CA    . LYS A 1 400 ? 165.528 204.739 193.389 1.00 58.68  ? 405 LYS M CA    1 
ATOM   3060 C C     . LYS A 1 400 ? 166.523 203.644 193.026 1.00 58.68  ? 405 LYS M C     1 
ATOM   3061 O O     . LYS A 1 400 ? 166.173 202.690 192.327 1.00 58.68  ? 405 LYS M O     1 
ATOM   3062 C CB    . LYS A 1 400 ? 164.339 204.136 194.130 1.00 58.68  ? 405 LYS M CB    1 
ATOM   3063 C CG    . LYS A 1 400 ? 164.712 203.494 195.439 1.00 58.68  ? 405 LYS M CG    1 
ATOM   3064 C CD    . LYS A 1 400 ? 163.490 203.009 196.172 1.00 58.68  ? 405 LYS M CD    1 
ATOM   3065 C CE    . LYS A 1 400 ? 163.835 202.571 197.577 1.00 58.68  ? 405 LYS M CE    1 
ATOM   3066 N NZ    . LYS A 1 400 ? 162.657 201.987 198.256 1.00 58.68  ? 405 LYS M NZ    1 
ATOM   3067 N N     . VAL A 1 401 ? 167.746 203.769 193.527 1.00 54.15  ? 406 VAL M N     1 
ATOM   3068 C CA    . VAL A 1 401 ? 168.795 202.774 193.341 1.00 54.15  ? 406 VAL M CA    1 
ATOM   3069 C C     . VAL A 1 401 ? 169.086 202.158 194.702 1.00 54.15  ? 406 VAL M C     1 
ATOM   3070 O O     . VAL A 1 401 ? 169.845 202.706 195.505 1.00 54.15  ? 406 VAL M O     1 
ATOM   3071 C CB    . VAL A 1 401 ? 170.048 203.379 192.705 1.00 54.15  ? 406 VAL M CB    1 
ATOM   3072 C CG1   . VAL A 1 401 ? 169.798 203.630 191.258 1.00 54.15  ? 406 VAL M CG1   1 
ATOM   3073 C CG2   . VAL A 1 401 ? 170.365 204.697 193.354 1.00 54.15  ? 406 VAL M CG2   1 
ATOM   3074 N N     . GLY A 1 402 ? 168.476 200.996 194.953 1.00 56.21  ? 407 GLY M N     1 
ATOM   3075 C CA    . GLY A 1 402 ? 168.657 200.286 196.233 1.00 56.21  ? 407 GLY M CA    1 
ATOM   3076 C C     . GLY A 1 402 ? 168.057 201.072 197.385 1.00 56.21  ? 407 GLY M C     1 
ATOM   3077 O O     . GLY A 1 402 ? 166.816 201.089 197.503 1.00 56.21  ? 407 GLY M O     1 
ATOM   3078 N N     . ASN A 1 403 ? 168.906 201.706 198.199 1.00 59.59  ? 408 ASN M N     1 
ATOM   3079 C CA    . ASN A 1 403 ? 168.433 202.512 199.356 1.00 59.59  ? 408 ASN M CA    1 
ATOM   3080 C C     . ASN A 1 403 ? 168.908 203.960 199.189 1.00 59.59  ? 408 ASN M C     1 
ATOM   3081 O O     . ASN A 1 403 ? 169.356 204.553 200.188 1.00 59.59  ? 408 ASN M O     1 
ATOM   3082 C CB    . ASN A 1 403 ? 168.897 201.918 200.689 1.00 59.59  ? 408 ASN M CB    1 
ATOM   3083 C CG    . ASN A 1 403 ? 168.188 200.627 201.038 1.00 59.59  ? 408 ASN M CG    1 
ATOM   3084 O OD1   . ASN A 1 403 ? 167.033 200.641 201.455 1.00 59.59  ? 408 ASN M OD1   1 
ATOM   3085 N ND2   . ASN A 1 403 ? 168.872 199.507 200.870 1.00 59.59  ? 408 ASN M ND2   1 
ATOM   3086 N N     . GLU A 1 404 ? 168.806 204.498 197.969 1.00 61.09  ? 409 GLU M N     1 
ATOM   3087 C CA    . GLU A 1 404 ? 169.238 205.893 197.687 1.00 61.09  ? 409 GLU M CA    1 
ATOM   3088 C C     . GLU A 1 404 ? 168.562 206.389 196.403 1.00 61.09  ? 409 GLU M C     1 
ATOM   3089 O O     . GLU A 1 404 ? 168.187 205.545 195.567 1.00 61.09  ? 409 GLU M O     1 
ATOM   3090 C CB    . GLU A 1 404 ? 170.760 205.958 197.551 1.00 61.09  ? 409 GLU M CB    1 
ATOM   3091 C CG    . GLU A 1 404 ? 171.301 205.147 196.388 1.00 61.09  ? 409 GLU M CG    1 
ATOM   3092 C CD    . GLU A 1 404 ? 172.816 205.094 196.299 1.00 61.09  ? 409 GLU M CD    1 
ATOM   3093 O OE1   . GLU A 1 404 ? 173.474 205.951 196.923 1.00 61.09  ? 409 GLU M OE1   1 
ATOM   3094 O OE2   . GLU A 1 404 ? 173.336 204.197 195.607 1.00 61.09  ? 409 GLU M OE2   1 
ATOM   3095 N N     . TYR A 1 405 ? 168.412 207.710 196.271 1.00 62.74  ? 410 TYR M N     1 
ATOM   3096 C CA    . TYR A 1 405 ? 167.811 208.325 195.096 1.00 62.74  ? 410 TYR M CA    1 
ATOM   3097 C C     . TYR A 1 405 ? 168.875 209.092 194.333 1.00 62.74  ? 410 TYR M C     1 
ATOM   3098 O O     . TYR A 1 405 ? 169.589 209.910 194.918 1.00 62.74  ? 410 TYR M O     1 
ATOM   3099 C CB    . TYR A 1 405 ? 166.678 209.280 195.469 1.00 62.74  ? 410 TYR M CB    1 
ATOM   3100 C CG    . TYR A 1 405 ? 165.428 208.629 195.994 1.00 62.74  ? 410 TYR M CG    1 
ATOM   3101 C CD1   . TYR A 1 405 ? 165.280 207.257 195.995 1.00 62.74  ? 410 TYR M CD1   1 
ATOM   3102 C CD2   . TYR A 1 405 ? 164.381 209.398 196.473 1.00 62.74  ? 410 TYR M CD2   1 
ATOM   3103 C CE1   . TYR A 1 405 ? 164.137 206.670 196.476 1.00 62.74  ? 410 TYR M CE1   1 
ATOM   3104 C CE2   . TYR A 1 405 ? 163.235 208.821 196.946 1.00 62.74  ? 410 TYR M CE2   1 
ATOM   3105 C CZ    . TYR A 1 405 ? 163.117 207.455 196.945 1.00 62.74  ? 410 TYR M CZ    1 
ATOM   3106 O OH    . TYR A 1 405 ? 161.972 206.867 197.423 1.00 62.74  ? 410 TYR M OH    1 
ATOM   3107 N N     . VAL A 1 406 ? 168.966 208.848 193.034 1.00 59.60  ? 411 VAL M N     1 
ATOM   3108 C CA    . VAL A 1 406 ? 169.873 209.584 192.170 1.00 59.60  ? 411 VAL M CA    1 
ATOM   3109 C C     . VAL A 1 406 ? 169.065 210.211 191.045 1.00 59.60  ? 411 VAL M C     1 
ATOM   3110 O O     . VAL A 1 406 ? 168.070 209.649 190.579 1.00 59.60  ? 411 VAL M O     1 
ATOM   3111 C CB    . VAL A 1 406 ? 170.994 208.684 191.617 1.00 59.60  ? 411 VAL M CB    1 
ATOM   3112 C CG1   . VAL A 1 406 ? 170.428 207.633 190.698 1.00 59.60  ? 411 VAL M CG1   1 
ATOM   3113 C CG2   . VAL A 1 406 ? 172.033 209.513 190.902 1.00 59.60  ? 411 VAL M CG2   1 
ATOM   3114 N N     . THR A 1 407 ? 169.488 211.396 190.625 1.00 60.31  ? 412 THR M N     1 
ATOM   3115 C CA    . THR A 1 407 ? 168.764 212.147 189.614 1.00 60.31  ? 412 THR M CA    1 
ATOM   3116 C C     . THR A 1 407 ? 169.100 211.667 188.210 1.00 60.31  ? 412 THR M C     1 
ATOM   3117 O O     . THR A 1 407 ? 170.266 211.493 187.857 1.00 60.31  ? 412 THR M O     1 
ATOM   3118 C CB    . THR A 1 407 ? 169.073 213.633 189.746 1.00 60.31  ? 412 THR M CB    1 
ATOM   3119 O OG1   . THR A 1 407 ? 168.445 214.348 188.680 1.00 60.31  ? 412 THR M OG1   1 
ATOM   3120 C CG2   . THR A 1 407 ? 170.563 213.881 189.734 1.00 60.31  ? 412 THR M CG2   1 
ATOM   3121 N N     . LYS A 1 408 ? 168.066 211.458 187.410 1.00 62.87  ? 413 LYS M N     1 
ATOM   3122 C CA    . LYS A 1 408 ? 168.201 211.022 186.032 1.00 62.87  ? 413 LYS M CA    1 
ATOM   3123 C C     . LYS A 1 408 ? 168.210 212.227 185.098 1.00 62.87  ? 413 LYS M C     1 
ATOM   3124 O O     . LYS A 1 408 ? 167.570 213.245 185.365 1.00 62.87  ? 413 LYS M O     1 
ATOM   3125 C CB    . LYS A 1 408 ? 167.061 210.072 185.672 1.00 62.87  ? 413 LYS M CB    1 
ATOM   3126 C CG    . LYS A 1 408 ? 167.188 209.434 184.326 1.00 62.87  ? 413 LYS M CG    1 
ATOM   3127 C CD    . LYS A 1 408 ? 166.266 208.244 184.197 1.00 62.87  ? 413 LYS M CD    1 
ATOM   3128 C CE    . LYS A 1 408 ? 166.563 207.477 182.915 1.00 62.87  ? 413 LYS M CE    1 
ATOM   3129 N NZ    . LYS A 1 408 ? 165.857 206.168 182.846 1.00 62.87  ? 413 LYS M NZ    1 
ATOM   3130 N N     . GLY A 1 409 ? 168.959 212.116 184.007 1.00 68.19  ? 414 GLY M N     1 
ATOM   3131 C CA    . GLY A 1 409 ? 169.036 213.184 183.031 1.00 68.19  ? 414 GLY M CA    1 
ATOM   3132 C C     . GLY A 1 409 ? 168.029 213.006 181.908 1.00 68.19  ? 414 GLY M C     1 
ATOM   3133 O O     . GLY A 1 409 ? 167.642 211.895 181.572 1.00 68.19  ? 414 GLY M O     1 
ATOM   3134 N N     . GLN A 1 410 ? 167.592 214.128 181.337 1.00 75.35  ? 415 GLN M N     1 
ATOM   3135 C CA    . GLN A 1 410 ? 166.624 214.114 180.250 1.00 75.35  ? 415 GLN M CA    1 
ATOM   3136 C C     . GLN A 1 410 ? 167.016 215.141 179.204 1.00 75.35  ? 415 GLN M C     1 
ATOM   3137 O O     . GLN A 1 410 ? 167.595 216.181 179.522 1.00 75.35  ? 415 GLN M O     1 
ATOM   3138 C CB    . GLN A 1 410 ? 165.205 214.416 180.733 1.00 75.35  ? 415 GLN M CB    1 
ATOM   3139 C CG    . GLN A 1 410 ? 164.692 213.518 181.824 1.00 75.35  ? 415 GLN M CG    1 
ATOM   3140 C CD    . GLN A 1 410 ? 164.133 212.226 181.308 1.00 75.35  ? 415 GLN M CD    1 
ATOM   3141 O OE1   . GLN A 1 410 ? 162.922 212.045 181.252 1.00 75.35  ? 415 GLN M OE1   1 
ATOM   3142 N NE2   . GLN A 1 410 ? 165.007 211.307 180.940 1.00 75.35  ? 415 GLN M NE2   1 
ATOM   3143 N N     . ASN A 1 411 ? 166.700 214.835 177.951 1.00 80.07  ? 416 ASN M N     1 
ATOM   3144 C CA    . ASN A 1 411 ? 166.798 215.776 176.849 1.00 80.07  ? 416 ASN M CA    1 
ATOM   3145 C C     . ASN A 1 411 ? 165.390 216.142 176.386 1.00 80.07  ? 416 ASN M C     1 
ATOM   3146 O O     . ASN A 1 411 ? 164.388 215.721 176.979 1.00 80.07  ? 416 ASN M O     1 
ATOM   3147 C CB    . ASN A 1 411 ? 167.648 215.195 175.718 1.00 80.07  ? 416 ASN M CB    1 
ATOM   3148 C CG    . ASN A 1 411 ? 167.142 213.854 175.235 1.00 80.07  ? 416 ASN M CG    1 
ATOM   3149 O OD1   . ASN A 1 411 ? 166.029 213.449 175.551 1.00 80.07  ? 416 ASN M OD1   1 
ATOM   3150 N ND2   . ASN A 1 411 ? 167.957 213.161 174.459 1.00 80.07  ? 416 ASN M ND2   1 
ATOM   3151 N N     . VAL A 1 412 ? 165.313 216.924 175.309 1.00 81.71  ? 417 VAL M N     1 
ATOM   3152 C CA    . VAL A 1 412 ? 164.031 217.484 174.894 1.00 81.71  ? 417 VAL M CA    1 
ATOM   3153 C C     . VAL A 1 412 ? 163.072 216.390 174.453 1.00 81.71  ? 417 VAL M C     1 
ATOM   3154 O O     . VAL A 1 412 ? 161.893 216.400 174.822 1.00 81.71  ? 417 VAL M O     1 
ATOM   3155 C CB    . VAL A 1 412 ? 164.244 218.533 173.793 1.00 81.71  ? 417 VAL M CB    1 
ATOM   3156 C CG1   . VAL A 1 412 ? 162.922 219.014 173.272 1.00 81.71  ? 417 VAL M CG1   1 
ATOM   3157 C CG2   . VAL A 1 412 ? 165.018 219.692 174.349 1.00 81.71  ? 417 VAL M CG2   1 
ATOM   3158 N N     . GLN A 1 413 ? 163.548 215.437 173.657 1.00 81.92  ? 418 GLN M N     1 
ATOM   3159 C CA    . GLN A 1 413 ? 162.671 214.362 173.217 1.00 81.92  ? 418 GLN M CA    1 
ATOM   3160 C C     . GLN A 1 413 ? 162.126 213.581 174.400 1.00 81.92  ? 418 GLN M C     1 
ATOM   3161 O O     . GLN A 1 413 ? 160.933 213.256 174.446 1.00 81.92  ? 418 GLN M O     1 
ATOM   3162 C CB    . GLN A 1 413 ? 163.419 213.434 172.269 1.00 81.92  ? 418 GLN M CB    1 
ATOM   3163 C CG    . GLN A 1 413 ? 164.084 214.152 171.134 1.00 81.92  ? 418 GLN M CG    1 
ATOM   3164 C CD    . GLN A 1 413 ? 163.085 214.763 170.184 1.00 81.92  ? 418 GLN M CD    1 
ATOM   3165 O OE1   . GLN A 1 413 ? 163.301 215.853 169.655 1.00 81.92  ? 418 GLN M OE1   1 
ATOM   3166 N NE2   . GLN A 1 413 ? 161.981 214.063 169.959 1.00 81.92  ? 418 GLN M NE2   1 
ATOM   3167 N N     . GLN A 1 414 ? 162.985 213.276 175.373 1.00 79.96  ? 419 GLN M N     1 
ATOM   3168 C CA    . GLN A 1 414 ? 162.548 212.492 176.520 1.00 79.96  ? 419 GLN M CA    1 
ATOM   3169 C C     . GLN A 1 414 ? 161.524 213.252 177.350 1.00 79.96  ? 419 GLN M C     1 
ATOM   3170 O O     . GLN A 1 414 ? 160.504 212.685 177.758 1.00 79.96  ? 419 GLN M O     1 
ATOM   3171 C CB    . GLN A 1 414 ? 163.749 212.101 177.374 1.00 79.96  ? 419 GLN M CB    1 
ATOM   3172 C CG    . GLN A 1 414 ? 164.586 210.993 176.793 1.00 79.96  ? 419 GLN M CG    1 
ATOM   3173 C CD    . GLN A 1 414 ? 165.908 210.839 177.503 1.00 79.96  ? 419 GLN M CD    1 
ATOM   3174 O OE1   . GLN A 1 414 ? 166.642 211.802 177.684 1.00 79.96  ? 419 GLN M OE1   1 
ATOM   3175 N NE2   . GLN A 1 414 ? 166.216 209.621 177.914 1.00 79.96  ? 419 GLN M NE2   1 
ATOM   3176 N N     . VAL A 1 415 ? 161.766 214.540 177.597 1.00 81.89  ? 420 VAL M N     1 
ATOM   3177 C CA    . VAL A 1 415 ? 160.821 215.287 178.414 1.00 81.89  ? 420 VAL M CA    1 
ATOM   3178 C C     . VAL A 1 415 ? 159.501 215.468 177.675 1.00 81.89  ? 420 VAL M C     1 
ATOM   3179 O O     . VAL A 1 415 ? 158.432 215.472 178.296 1.00 81.89  ? 420 VAL M O     1 
ATOM   3180 C CB    . VAL A 1 415 ? 161.434 216.628 178.849 1.00 81.89  ? 420 VAL M CB    1 
ATOM   3181 C CG1   . VAL A 1 415 ? 161.748 217.473 177.667 1.00 81.89  ? 420 VAL M CG1   1 
ATOM   3182 C CG2   . VAL A 1 415 ? 160.507 217.352 179.769 1.00 81.89  ? 420 VAL M CG2   1 
ATOM   3183 N N     . ILE A 1 416 ? 159.535 215.565 176.345 1.00 81.88  ? 421 ILE M N     1 
ATOM   3184 C CA    . ILE A 1 416 ? 158.295 215.691 175.587 1.00 81.88  ? 421 ILE M CA    1 
ATOM   3185 C C     . ILE A 1 416 ? 157.497 214.395 175.634 1.00 81.88  ? 421 ILE M C     1 
ATOM   3186 O O     . ILE A 1 416 ? 156.271 214.411 175.809 1.00 81.88  ? 421 ILE M O     1 
ATOM   3187 C CB    . ILE A 1 416 ? 158.604 216.116 174.144 1.00 81.88  ? 421 ILE M CB    1 
ATOM   3188 C CG1   . ILE A 1 416 ? 158.849 217.620 174.082 1.00 81.88  ? 421 ILE M CG1   1 
ATOM   3189 C CG2   . ILE A 1 416 ? 157.483 215.721 173.221 1.00 81.88  ? 421 ILE M CG2   1 
ATOM   3190 C CD1   . ILE A 1 416 ? 159.379 218.078 172.760 1.00 81.88  ? 421 ILE M CD1   1 
ATOM   3191 N N     . TYR A 1 417 ? 158.170 213.255 175.469 1.00 82.79  ? 422 TYR M N     1 
ATOM   3192 C CA    . TYR A 1 417 ? 157.476 211.979 175.601 1.00 82.79  ? 422 TYR M CA    1 
ATOM   3193 C C     . TYR A 1 417 ? 156.880 211.827 176.991 1.00 82.79  ? 422 TYR M C     1 
ATOM   3194 O O     . TYR A 1 417 ? 155.765 211.315 177.148 1.00 82.79  ? 422 TYR M O     1 
ATOM   3195 C CB    . TYR A 1 417 ? 158.425 210.821 175.311 1.00 82.79  ? 422 TYR M CB    1 
ATOM   3196 C CG    . TYR A 1 417 ? 159.068 210.864 173.951 1.00 82.79  ? 422 TYR M CG    1 
ATOM   3197 C CD1   . TYR A 1 417 ? 158.440 211.478 172.884 1.00 82.79  ? 422 TYR M CD1   1 
ATOM   3198 C CD2   . TYR A 1 417 ? 160.308 210.291 173.737 1.00 82.79  ? 422 TYR M CD2   1 
ATOM   3199 C CE1   . TYR A 1 417 ? 159.027 211.519 171.643 1.00 82.79  ? 422 TYR M CE1   1 
ATOM   3200 C CE2   . TYR A 1 417 ? 160.902 210.327 172.499 1.00 82.79  ? 422 TYR M CE2   1 
ATOM   3201 C CZ    . TYR A 1 417 ? 160.257 210.942 171.455 1.00 82.79  ? 422 TYR M CZ    1 
ATOM   3202 O OH    . TYR A 1 417 ? 160.850 210.981 170.218 1.00 82.79  ? 422 TYR M OH    1 
ATOM   3203 N N     . ALA A 1 418 ? 157.605 212.277 178.014 1.00 84.66  ? 423 ALA M N     1 
ATOM   3204 C CA    . ALA A 1 418 ? 157.080 212.188 179.370 1.00 84.66  ? 423 ALA M CA    1 
ATOM   3205 C C     . ALA A 1 418 ? 155.850 213.063 179.541 1.00 84.66  ? 423 ALA M C     1 
ATOM   3206 O O     . ALA A 1 418 ? 154.877 212.651 180.178 1.00 84.66  ? 423 ALA M O     1 
ATOM   3207 C CB    . ALA A 1 418 ? 158.156 212.575 180.377 1.00 84.66  ? 423 ALA M CB    1 
ATOM   3208 N N     . THR A 1 419 ? 155.874 214.274 178.982 1.00 86.14  ? 424 THR M N     1 
ATOM   3209 C CA    . THR A 1 419 ? 154.719 215.161 179.079 1.00 86.14  ? 424 THR M CA    1 
ATOM   3210 C C     . THR A 1 419 ? 153.499 214.542 178.409 1.00 86.14  ? 424 THR M C     1 
ATOM   3211 O O     . THR A 1 419 ? 152.392 214.553 178.963 1.00 86.14  ? 424 THR M O     1 
ATOM   3212 C CB    . THR A 1 419 ? 155.046 216.512 178.449 1.00 86.14  ? 424 THR M CB    1 
ATOM   3213 O OG1   . THR A 1 419 ? 156.257 217.017 179.014 1.00 86.14  ? 424 THR M OG1   1 
ATOM   3214 C CG2   . THR A 1 419 ? 153.946 217.492 178.722 1.00 86.14  ? 424 THR M CG2   1 
ATOM   3215 N N     . GLY A 1 420 ? 153.688 214.000 177.208 1.00 89.58  ? 425 GLY M N     1 
ATOM   3216 C CA    . GLY A 1 420 ? 152.585 213.357 176.520 1.00 89.58  ? 425 GLY M CA    1 
ATOM   3217 C C     . GLY A 1 420 ? 152.022 212.184 177.295 1.00 89.58  ? 425 GLY M C     1 
ATOM   3218 O O     . GLY A 1 420 ? 150.802 212.010 177.382 1.00 89.58  ? 425 GLY M O     1 
ATOM   3219 N N     . ALA A 1 421 ? 152.901 211.361 177.868 1.00 89.98  ? 426 ALA M N     1 
ATOM   3220 C CA    . ALA A 1 421 ? 152.426 210.213 178.629 1.00 89.98  ? 426 ALA M CA    1 
ATOM   3221 C C     . ALA A 1 421 ? 151.706 210.655 179.892 1.00 89.98  ? 426 ALA M C     1 
ATOM   3222 O O     . ALA A 1 421 ? 150.712 210.043 180.290 1.00 89.98  ? 426 ALA M O     1 
ATOM   3223 C CB    . ALA A 1 421 ? 153.587 209.285 178.964 1.00 89.98  ? 426 ALA M CB    1 
ATOM   3224 N N     . LEU A 1 422 ? 152.174 211.732 180.521 1.00 90.90  ? 427 LEU M N     1 
ATOM   3225 C CA    . LEU A 1 422 ? 151.493 212.259 181.698 1.00 90.90  ? 427 LEU M CA    1 
ATOM   3226 C C     . LEU A 1 422 ? 150.087 212.726 181.351 1.00 90.90  ? 427 LEU M C     1 
ATOM   3227 O O     . LEU A 1 422 ? 149.127 212.433 182.071 1.00 90.90  ? 427 LEU M O     1 
ATOM   3228 C CB    . LEU A 1 422 ? 152.303 213.405 182.299 1.00 90.90  ? 427 LEU M CB    1 
ATOM   3229 C CG    . LEU A 1 422 ? 153.516 213.010 183.135 1.00 90.90  ? 427 LEU M CG    1 
ATOM   3230 C CD1   . LEU A 1 422 ? 154.371 214.223 183.430 1.00 90.90  ? 427 LEU M CD1   1 
ATOM   3231 C CD2   . LEU A 1 422 ? 153.066 212.349 184.418 1.00 90.90  ? 427 LEU M CD2   1 
ATOM   3232 N N     . ALA A 1 423 ? 149.952 213.469 180.253 1.00 95.35  ? 428 ALA M N     1 
ATOM   3233 C CA    . ALA A 1 423 ? 148.635 213.943 179.838 1.00 95.35  ? 428 ALA M CA    1 
ATOM   3234 C C     . ALA A 1 423 ? 147.704 212.778 179.529 1.00 95.35  ? 428 ALA M C     1 
ATOM   3235 O O     . ALA A 1 423 ? 146.560 212.742 179.998 1.00 95.35  ? 428 ALA M O     1 
ATOM   3236 C CB    . ALA A 1 423 ? 148.765 214.863 178.628 1.00 95.35  ? 428 ALA M CB    1 
ATOM   3237 N N     . LYS A 1 424 ? 148.168 211.821 178.724 1.00 96.45  ? 429 LYS M N     1 
ATOM   3238 C CA    . LYS A 1 424 ? 147.332 210.663 178.430 1.00 96.45  ? 429 LYS M CA    1 
ATOM   3239 C C     . LYS A 1 424 ? 146.923 209.950 179.708 1.00 96.45  ? 429 LYS M C     1 
ATOM   3240 O O     . LYS A 1 424 ? 145.768 209.533 179.856 1.00 96.45  ? 429 LYS M O     1 
ATOM   3241 C CB    . LYS A 1 424 ? 148.061 209.701 177.497 1.00 96.45  ? 429 LYS M CB    1 
ATOM   3242 C CG    . LYS A 1 424 ? 148.351 210.274 176.133 1.00 96.45  ? 429 LYS M CG    1 
ATOM   3243 C CD    . LYS A 1 424 ? 148.830 209.210 175.179 1.00 96.45  ? 429 LYS M CD    1 
ATOM   3244 C CE    . LYS A 1 424 ? 150.198 208.707 175.563 1.00 96.45  ? 429 LYS M CE    1 
ATOM   3245 N NZ    . LYS A 1 424 ? 150.738 207.754 174.555 1.00 96.45  ? 429 LYS M NZ    1 
ATOM   3246 N N     . ALA A 1 425 ? 147.849 209.827 180.656 1.00 98.73  ? 430 ALA M N     1 
ATOM   3247 C CA    . ALA A 1 425 ? 147.553 209.123 181.893 1.00 98.73  ? 430 ALA M CA    1 
ATOM   3248 C C     . ALA A 1 425 ? 146.486 209.845 182.697 1.00 98.73  ? 430 ALA M C     1 
ATOM   3249 O O     . ALA A 1 425 ? 145.519 209.226 183.150 1.00 98.73  ? 430 ALA M O     1 
ATOM   3250 C CB    . ALA A 1 425 ? 148.827 208.964 182.716 1.00 98.73  ? 430 ALA M CB    1 
ATOM   3251 N N     . VAL A 1 426 ? 146.649 211.154 182.899 1.00 102.63 ? 431 VAL M N     1 
ATOM   3252 C CA    . VAL A 1 426 ? 145.695 211.883 183.728 1.00 102.63 ? 431 VAL M CA    1 
ATOM   3253 C C     . VAL A 1 426 ? 144.321 211.886 183.076 1.00 102.63 ? 431 VAL M C     1 
ATOM   3254 O O     . VAL A 1 426 ? 143.298 211.742 183.758 1.00 102.63 ? 431 VAL M O     1 
ATOM   3255 C CB    . VAL A 1 426 ? 146.193 213.309 184.028 1.00 102.63 ? 431 VAL M CB    1 
ATOM   3256 C CG1   . VAL A 1 426 ? 146.424 214.088 182.764 1.00 102.63 ? 431 VAL M CG1   1 
ATOM   3257 C CG2   . VAL A 1 426 ? 145.202 214.037 184.902 1.00 102.63 ? 431 VAL M CG2   1 
ATOM   3258 N N     . TYR A 1 427 ? 144.269 212.009 181.747 1.00 107.48 ? 432 TYR M N     1 
ATOM   3259 C CA    . TYR A 1 427 ? 142.978 211.963 181.073 1.00 107.48 ? 432 TYR M CA    1 
ATOM   3260 C C     . TYR A 1 427 ? 142.304 210.617 181.284 1.00 107.48 ? 432 TYR M C     1 
ATOM   3261 O O     . TYR A 1 427 ? 141.143 210.552 181.701 1.00 107.48 ? 432 TYR M O     1 
ATOM   3262 C CB    . TYR A 1 427 ? 143.142 212.251 179.583 1.00 107.48 ? 432 TYR M CB    1 
ATOM   3263 C CG    . TYR A 1 427 ? 141.844 212.168 178.818 1.00 107.48 ? 432 TYR M CG    1 
ATOM   3264 C CD1   . TYR A 1 427 ? 141.409 210.964 178.281 1.00 107.48 ? 432 TYR M CD1   1 
ATOM   3265 C CD2   . TYR A 1 427 ? 141.050 213.290 178.635 1.00 107.48 ? 432 TYR M CD2   1 
ATOM   3266 C CE1   . TYR A 1 427 ? 140.225 210.878 177.591 1.00 107.48 ? 432 TYR M CE1   1 
ATOM   3267 C CE2   . TYR A 1 427 ? 139.863 213.212 177.941 1.00 107.48 ? 432 TYR M CE2   1 
ATOM   3268 C CZ    . TYR A 1 427 ? 139.456 212.001 177.421 1.00 107.48 ? 432 TYR M CZ    1 
ATOM   3269 O OH    . TYR A 1 427 ? 138.273 211.905 176.727 1.00 107.48 ? 432 TYR M OH    1 
ATOM   3270 N N     . GLU A 1 428 ? 143.015 209.528 180.993 1.00 107.75 ? 433 GLU M N     1 
ATOM   3271 C CA    . GLU A 1 428 ? 142.425 208.205 181.146 1.00 107.75 ? 433 GLU M CA    1 
ATOM   3272 C C     . GLU A 1 428 ? 142.028 207.935 182.593 1.00 107.75 ? 433 GLU M C     1 
ATOM   3273 O O     . GLU A 1 428 ? 141.014 207.276 182.856 1.00 107.75 ? 433 GLU M O     1 
ATOM   3274 C CB    . GLU A 1 428 ? 143.404 207.150 180.633 1.00 107.75 ? 433 GLU M CB    1 
ATOM   3275 C CG    . GLU A 1 428 ? 143.392 205.830 181.376 1.00 107.75 ? 433 GLU M CG    1 
ATOM   3276 C CD    . GLU A 1 428 ? 142.170 204.996 181.087 1.00 107.75 ? 433 GLU M CD    1 
ATOM   3277 O OE1   . GLU A 1 428 ? 141.288 205.452 180.332 1.00 107.75 ? 433 GLU M OE1   1 
ATOM   3278 O OE2   . GLU A 1 428 ? 142.090 203.872 181.620 1.00 107.75 ? 433 GLU M OE2   1 
ATOM   3279 N N     . ARG A 1 429 ? 142.800 208.457 183.546 1.00 106.60 ? 434 ARG M N     1 
ATOM   3280 C CA    . ARG A 1 429 ? 142.482 208.277 184.958 1.00 106.60 ? 434 ARG M CA    1 
ATOM   3281 C C     . ARG A 1 429 ? 141.177 208.968 185.317 1.00 106.60 ? 434 ARG M C     1 
ATOM   3282 O O     . ARG A 1 429 ? 140.287 208.366 185.936 1.00 106.60 ? 434 ARG M O     1 
ATOM   3283 C CB    . ARG A 1 429 ? 143.625 208.821 185.812 1.00 106.60 ? 434 ARG M CB    1 
ATOM   3284 C CG    . ARG A 1 429 ? 144.778 207.867 185.977 1.00 106.60 ? 434 ARG M CG    1 
ATOM   3285 C CD    . ARG A 1 429 ? 144.407 206.797 186.968 1.00 106.60 ? 434 ARG M CD    1 
ATOM   3286 N NE    . ARG A 1 429 ? 145.259 205.622 186.861 1.00 106.60 ? 434 ARG M NE    1 
ATOM   3287 C CZ    . ARG A 1 429 ? 146.450 205.506 187.433 1.00 106.60 ? 434 ARG M CZ    1 
ATOM   3288 N NH1   . ARG A 1 429 ? 146.949 206.497 188.154 1.00 106.60 ? 434 ARG M NH1   1 
ATOM   3289 N NH2   . ARG A 1 429 ? 147.141 204.393 187.274 1.00 106.60 ? 434 ARG M NH2   1 
ATOM   3290 N N     . MET A 1 430 ? 141.059 210.245 184.949 1.00 111.03 ? 435 MET M N     1 
ATOM   3291 C CA    . MET A 1 430 ? 139.820 210.980 185.172 1.00 111.03 ? 435 MET M CA    1 
ATOM   3292 C C     . MET A 1 430 ? 138.641 210.284 184.508 1.00 111.03 ? 435 MET M C     1 
ATOM   3293 O O     . MET A 1 430 ? 137.547 210.224 185.076 1.00 111.03 ? 435 MET M O     1 
ATOM   3294 C CB    . MET A 1 430 ? 139.984 212.412 184.666 1.00 111.03 ? 435 MET M CB    1 
ATOM   3295 C CG    . MET A 1 430 ? 138.708 213.176 184.441 1.00 111.03 ? 435 MET M CG    1 
ATOM   3296 S SD    . MET A 1 430 ? 139.062 214.914 184.117 1.00 111.03 ? 435 MET M SD    1 
ATOM   3297 C CE    . MET A 1 430 ? 140.190 214.800 182.737 1.00 111.03 ? 435 MET M CE    1 
ATOM   3298 N N     . PHE A 1 431 ? 138.853 209.722 183.320 1.00 113.01 ? 436 PHE M N     1 
ATOM   3299 C CA    . PHE A 1 431 ? 137.778 209.020 182.630 1.00 113.01 ? 436 PHE M CA    1 
ATOM   3300 C C     . PHE A 1 431 ? 137.315 207.803 183.420 1.00 113.01 ? 436 PHE M C     1 
ATOM   3301 O O     . PHE A 1 431 ? 136.112 207.609 183.644 1.00 113.01 ? 436 PHE M O     1 
ATOM   3302 C CB    . PHE A 1 431 ? 138.246 208.612 181.237 1.00 113.01 ? 436 PHE M CB    1 
ATOM   3303 C CG    . PHE A 1 431 ? 137.183 207.980 180.399 1.00 113.01 ? 436 PHE M CG    1 
ATOM   3304 C CD1   . PHE A 1 431 ? 136.421 208.741 179.541 1.00 113.01 ? 436 PHE M CD1   1 
ATOM   3305 C CD2   . PHE A 1 431 ? 136.951 206.624 180.459 1.00 113.01 ? 436 PHE M CD2   1 
ATOM   3306 C CE1   . PHE A 1 431 ? 135.447 208.163 178.766 1.00 113.01 ? 436 PHE M CE1   1 
ATOM   3307 C CE2   . PHE A 1 431 ? 135.982 206.048 179.688 1.00 113.01 ? 436 PHE M CE2   1 
ATOM   3308 C CZ    . PHE A 1 431 ? 135.229 206.817 178.839 1.00 113.01 ? 436 PHE M CZ    1 
ATOM   3309 N N     . ASN A 1 432 ? 138.255 206.952 183.828 1.00 113.15 ? 437 ASN M N     1 
ATOM   3310 C CA    . ASN A 1 432 ? 137.867 205.753 184.562 1.00 113.15 ? 437 ASN M CA    1 
ATOM   3311 C C     . ASN A 1 432 ? 137.162 206.113 185.858 1.00 113.15 ? 437 ASN M C     1 
ATOM   3312 O O     . ASN A 1 432 ? 136.177 205.470 186.241 1.00 113.15 ? 437 ASN M O     1 
ATOM   3313 C CB    . ASN A 1 432 ? 139.087 204.881 184.841 1.00 113.15 ? 437 ASN M CB    1 
ATOM   3314 C CG    . ASN A 1 432 ? 139.631 204.233 183.592 1.00 113.15 ? 437 ASN M CG    1 
ATOM   3315 O OD1   . ASN A 1 432 ? 139.579 204.815 182.513 1.00 113.15 ? 437 ASN M OD1   1 
ATOM   3316 N ND2   . ASN A 1 432 ? 140.163 203.024 183.730 1.00 113.15 ? 437 ASN M ND2   1 
ATOM   3317 N N     . TRP A 1 433 ? 137.632 207.159 186.537 1.00 114.39 ? 438 TRP M N     1 
ATOM   3318 C CA    . TRP A 1 433 ? 136.998 207.541 187.793 1.00 114.39 ? 438 TRP M CA    1 
ATOM   3319 C C     . TRP A 1 433 ? 135.611 208.127 187.558 1.00 114.39 ? 438 TRP M C     1 
ATOM   3320 O O     . TRP A 1 433 ? 134.702 207.933 188.374 1.00 114.39 ? 438 TRP M O     1 
ATOM   3321 C CB    . TRP A 1 433 ? 137.889 208.522 188.541 1.00 114.39 ? 438 TRP M CB    1 
ATOM   3322 C CG    . TRP A 1 433 ? 137.193 209.230 189.628 1.00 114.39 ? 438 TRP M CG    1 
ATOM   3323 C CD1   . TRP A 1 433 ? 136.889 208.745 190.862 1.00 114.39 ? 438 TRP M CD1   1 
ATOM   3324 C CD2   . TRP A 1 433 ? 136.707 210.568 189.588 1.00 114.39 ? 438 TRP M CD2   1 
ATOM   3325 N NE1   . TRP A 1 433 ? 136.241 209.703 191.597 1.00 114.39 ? 438 TRP M NE1   1 
ATOM   3326 C CE2   . TRP A 1 433 ? 136.117 210.833 190.834 1.00 114.39 ? 438 TRP M CE2   1 
ATOM   3327 C CE3   . TRP A 1 433 ? 136.711 211.568 188.617 1.00 114.39 ? 438 TRP M CE3   1 
ATOM   3328 C CZ2   . TRP A 1 433 ? 135.536 212.056 191.133 1.00 114.39 ? 438 TRP M CZ2   1 
ATOM   3329 C CZ3   . TRP A 1 433 ? 136.134 212.775 188.915 1.00 114.39 ? 438 TRP M CZ3   1 
ATOM   3330 C CH2   . TRP A 1 433 ? 135.556 213.012 190.162 1.00 114.39 ? 438 TRP M CH2   1 
ATOM   3331 N N     . MET A 1 434 ? 135.427 208.844 186.449 1.00 117.17 ? 439 MET M N     1 
ATOM   3332 C CA    . MET A 1 434 ? 134.096 209.323 186.095 1.00 117.17 ? 439 MET M CA    1 
ATOM   3333 C C     . MET A 1 434 ? 133.147 208.160 185.869 1.00 117.17 ? 439 MET M C     1 
ATOM   3334 O O     . MET A 1 434 ? 131.979 208.213 186.267 1.00 117.17 ? 439 MET M O     1 
ATOM   3335 C CB    . MET A 1 434 ? 134.171 210.204 184.850 1.00 117.17 ? 439 MET M CB    1 
ATOM   3336 C CG    . MET A 1 434 ? 132.826 210.555 184.247 1.00 117.17 ? 439 MET M CG    1 
ATOM   3337 S SD    . MET A 1 434 ? 132.290 209.422 182.952 1.00 117.17 ? 439 MET M SD    1 
ATOM   3338 C CE    . MET A 1 434 ? 133.550 209.703 181.715 1.00 117.17 ? 439 MET M CE    1 
ATOM   3339 N N     . VAL A 1 435 ? 133.630 207.099 185.227 1.00 117.61 ? 440 VAL M N     1 
ATOM   3340 C CA    . VAL A 1 435 ? 132.784 205.925 185.039 1.00 117.61 ? 440 VAL M CA    1 
ATOM   3341 C C     . VAL A 1 435 ? 132.452 205.287 186.381 1.00 117.61 ? 440 VAL M C     1 
ATOM   3342 O O     . VAL A 1 435 ? 131.332 204.805 186.593 1.00 117.61 ? 440 VAL M O     1 
ATOM   3343 C CB    . VAL A 1 435 ? 133.451 204.924 184.083 1.00 117.61 ? 440 VAL M CB    1 
ATOM   3344 C CG1   . VAL A 1 435 ? 132.631 203.657 183.999 1.00 117.61 ? 440 VAL M CG1   1 
ATOM   3345 C CG2   . VAL A 1 435 ? 133.609 205.543 182.714 1.00 117.61 ? 440 VAL M CG2   1 
ATOM   3346 N N     . THR A 1 436 ? 133.412 205.269 187.309 1.00 120.30 ? 441 THR M N     1 
ATOM   3347 C CA    . THR A 1 436 ? 133.114 204.748 188.644 1.00 120.30 ? 441 THR M CA    1 
ATOM   3348 C C     . THR A 1 436 ? 132.036 205.575 189.331 1.00 120.30 ? 441 THR M C     1 
ATOM   3349 O O     . THR A 1 436 ? 131.140 205.027 189.985 1.00 120.30 ? 441 THR M O     1 
ATOM   3350 C CB    . THR A 1 436 ? 134.368 204.716 189.511 1.00 120.30 ? 441 THR M CB    1 
ATOM   3351 O OG1   . THR A 1 436 ? 134.724 206.052 189.882 1.00 120.30 ? 441 THR M OG1   1 
ATOM   3352 C CG2   . THR A 1 436 ? 135.516 204.049 188.791 1.00 120.30 ? 441 THR M CG2   1 
ATOM   3353 N N     . ARG A 1 437 ? 132.112 206.899 189.201 1.00 123.44 ? 442 ARG M N     1 
ATOM   3354 C CA    . ARG A 1 437 ? 131.089 207.763 189.783 1.00 123.44 ? 442 ARG M CA    1 
ATOM   3355 C C     . ARG A 1 437 ? 129.726 207.499 189.157 1.00 123.44 ? 442 ARG M C     1 
ATOM   3356 O O     . ARG A 1 437 ? 128.706 207.453 189.858 1.00 123.44 ? 442 ARG M O     1 
ATOM   3357 C CB    . ARG A 1 437 ? 131.484 209.226 189.604 1.00 123.44 ? 442 ARG M CB    1 
ATOM   3358 C CG    . ARG A 1 437 ? 130.373 210.200 189.897 1.00 123.44 ? 442 ARG M CG    1 
ATOM   3359 C CD    . ARG A 1 437 ? 130.098 210.266 191.384 1.00 123.44 ? 442 ARG M CD    1 
ATOM   3360 N NE    . ARG A 1 437 ? 131.077 211.091 192.080 1.00 123.44 ? 442 ARG M NE    1 
ATOM   3361 C CZ    . ARG A 1 437 ? 131.045 211.341 193.383 1.00 123.44 ? 442 ARG M CZ    1 
ATOM   3362 N NH1   . ARG A 1 437 ? 130.083 210.821 194.129 1.00 123.44 ? 442 ARG M NH1   1 
ATOM   3363 N NH2   . ARG A 1 437 ? 131.973 212.107 193.939 1.00 123.44 ? 442 ARG M NH2   1 
ATOM   3364 N N     . ILE A 1 438 ? 129.689 207.339 187.834 1.00 124.47 ? 443 ILE M N     1 
ATOM   3365 C CA    . ILE A 1 438 ? 128.443 207.015 187.147 1.00 124.47 ? 443 ILE M CA    1 
ATOM   3366 C C     . ILE A 1 438 ? 127.851 205.729 187.703 1.00 124.47 ? 443 ILE M C     1 
ATOM   3367 O O     . ILE A 1 438 ? 126.653 205.647 188.003 1.00 124.47 ? 443 ILE M O     1 
ATOM   3368 C CB    . ILE A 1 438 ? 128.682 206.912 185.631 1.00 124.47 ? 443 ILE M CB    1 
ATOM   3369 C CG1   . ILE A 1 438 ? 128.871 208.302 185.027 1.00 124.47 ? 443 ILE M CG1   1 
ATOM   3370 C CG2   . ILE A 1 438 ? 127.558 206.146 184.951 1.00 124.47 ? 443 ILE M CG2   1 
ATOM   3371 C CD1   . ILE A 1 438 ? 127.832 209.306 185.467 1.00 124.47 ? 443 ILE M CD1   1 
ATOM   3372 N N     . ASN A 1 439 ? 128.683 204.702 187.844 1.00 127.15 ? 444 ASN M N     1 
ATOM   3373 C CA    . ASN A 1 439 ? 128.182 203.427 188.338 1.00 127.15 ? 444 ASN M CA    1 
ATOM   3374 C C     . ASN A 1 439 ? 127.714 203.543 189.782 1.00 127.15 ? 444 ASN M C     1 
ATOM   3375 O O     . ASN A 1 439 ? 126.763 202.868 190.189 1.00 127.15 ? 444 ASN M O     1 
ATOM   3376 C CB    . ASN A 1 439 ? 129.254 202.353 188.203 1.00 127.15 ? 444 ASN M CB    1 
ATOM   3377 C CG    . ASN A 1 439 ? 128.675 201.009 187.854 1.00 127.15 ? 444 ASN M CG    1 
ATOM   3378 O OD1   . ASN A 1 439 ? 127.739 200.916 187.065 1.00 127.15 ? 444 ASN M OD1   1 
ATOM   3379 N ND2   . ASN A 1 439 ? 129.219 199.956 188.448 1.00 127.15 ? 444 ASN M ND2   1 
ATOM   3380 N N     . ALA A 1 440 ? 128.368 204.395 190.572 1.00 128.52 ? 445 ALA M N     1 
ATOM   3381 C CA    . ALA A 1 440 ? 127.929 204.600 191.947 1.00 128.52 ? 445 ALA M CA    1 
ATOM   3382 C C     . ALA A 1 440 ? 126.564 205.270 191.993 1.00 128.52 ? 445 ALA M C     1 
ATOM   3383 O O     . ALA A 1 440 ? 125.714 204.903 192.811 1.00 128.52 ? 445 ALA M O     1 
ATOM   3384 C CB    . ALA A 1 440 ? 128.956 205.432 192.711 1.00 128.52 ? 445 ALA M CB    1 
ATOM   3385 N N     . THR A 1 441 ? 126.344 206.265 191.131 1.00 129.80 ? 446 THR M N     1 
ATOM   3386 C CA    . THR A 1 441 ? 125.017 206.866 191.016 1.00 129.80 ? 446 THR M CA    1 
ATOM   3387 C C     . THR A 1 441 ? 123.976 205.816 190.645 1.00 129.80 ? 446 THR M C     1 
ATOM   3388 O O     . THR A 1 441 ? 122.913 205.726 191.267 1.00 129.80 ? 446 THR M O     1 
ATOM   3389 C CB    . THR A 1 441 ? 125.032 207.989 189.978 1.00 129.80 ? 446 THR M CB    1 
ATOM   3390 O OG1   . THR A 1 441 ? 125.752 209.116 190.493 1.00 129.80 ? 446 THR M OG1   1 
ATOM   3391 C CG2   . THR A 1 441 ? 123.620 208.408 189.631 1.00 129.80 ? 446 THR M CG2   1 
ATOM   3392 N N     . LEU A 1 442 ? 124.282 204.996 189.641 1.00 132.51 ? 447 LEU M N     1 
ATOM   3393 C CA    . LEU A 1 442 ? 123.333 203.984 189.194 1.00 132.51 ? 447 LEU M CA    1 
ATOM   3394 C C     . LEU A 1 442 ? 123.086 202.924 190.258 1.00 132.51 ? 447 LEU M C     1 
ATOM   3395 O O     . LEU A 1 442 ? 122.025 202.293 190.262 1.00 132.51 ? 447 LEU M O     1 
ATOM   3396 C CB    . LEU A 1 442 ? 123.842 203.329 187.909 1.00 132.51 ? 447 LEU M CB    1 
ATOM   3397 C CG    . LEU A 1 442 ? 122.887 202.559 186.992 1.00 132.51 ? 447 LEU M CG    1 
ATOM   3398 C CD1   . LEU A 1 442 ? 123.450 202.517 185.581 1.00 132.51 ? 447 LEU M CD1   1 
ATOM   3399 C CD2   . LEU A 1 442 ? 122.625 201.146 187.484 1.00 132.51 ? 447 LEU M CD2   1 
ATOM   3400 N N     . GLU A 1 443 ? 124.034 202.726 191.169 1.00 137.15 ? 448 GLU M N     1 
ATOM   3401 C CA    . GLU A 1 443 ? 124.047 201.530 192.004 1.00 137.15 ? 448 GLU M CA    1 
ATOM   3402 C C     . GLU A 1 443 ? 122.804 201.420 192.876 1.00 137.15 ? 448 GLU M C     1 
ATOM   3403 O O     . GLU A 1 443 ? 122.425 202.368 193.569 1.00 137.15 ? 448 GLU M O     1 
ATOM   3404 C CB    . GLU A 1 443 ? 125.297 201.524 192.880 1.00 137.15 ? 448 GLU M CB    1 
ATOM   3405 C CG    . GLU A 1 443 ? 125.433 200.280 193.729 1.00 137.15 ? 448 GLU M CG    1 
ATOM   3406 C CD    . GLU A 1 443 ? 125.104 200.532 195.180 1.00 137.15 ? 448 GLU M CD    1 
ATOM   3407 O OE1   . GLU A 1 443 ? 124.616 199.595 195.846 1.00 137.15 ? 448 GLU M OE1   1 
ATOM   3408 O OE2   . GLU A 1 443 ? 125.334 201.666 195.654 1.00 137.15 ? 448 GLU M OE2   1 
ATOM   3409 N N     . THR A 1 444 ? 122.172 200.252 192.835 1.00 141.49 ? 449 THR M N     1 
ATOM   3410 C CA    . THR A 1 444 ? 121.053 199.909 193.697 1.00 141.49 ? 449 THR M CA    1 
ATOM   3411 C C     . THR A 1 444 ? 121.460 198.759 194.609 1.00 141.49 ? 449 THR M C     1 
ATOM   3412 O O     . THR A 1 444 ? 122.211 197.863 194.215 1.00 141.49 ? 449 THR M O     1 
ATOM   3413 C CB    . THR A 1 444 ? 119.822 199.522 192.867 1.00 141.49 ? 449 THR M CB    1 
ATOM   3414 O OG1   . THR A 1 444 ? 119.433 200.628 192.045 1.00 141.49 ? 449 THR M OG1   1 
ATOM   3415 C CG2   . THR A 1 444 ? 118.654 199.136 193.758 1.00 141.49 ? 449 THR M CG2   1 
ATOM   3416 N N     . LYS A 1 445 ? 120.942 198.781 195.836 1.00 142.36 ? 450 LYS M N     1 
ATOM   3417 C CA    . LYS A 1 445 ? 121.355 197.833 196.864 1.00 142.36 ? 450 LYS M CA    1 
ATOM   3418 C C     . LYS A 1 445 ? 120.757 196.447 196.684 1.00 142.36 ? 450 LYS M C     1 
ATOM   3419 O O     . LYS A 1 445 ? 121.103 195.545 197.451 1.00 142.36 ? 450 LYS M O     1 
ATOM   3420 C CB    . LYS A 1 445 ? 120.978 198.364 198.247 1.00 142.36 ? 450 LYS M CB    1 
ATOM   3421 C CG    . LYS A 1 445 ? 121.556 199.733 198.582 1.00 142.36 ? 450 LYS M CG    1 
ATOM   3422 C CD    . LYS A 1 445 ? 123.073 199.724 198.605 1.00 142.36 ? 450 LYS M CD    1 
ATOM   3423 C CE    . LYS A 1 445 ? 123.625 198.625 199.507 1.00 142.36 ? 450 LYS M CE    1 
ATOM   3424 N NZ    . LYS A 1 445 ? 122.836 198.443 200.758 1.00 142.36 ? 450 LYS M NZ    1 
ATOM   3425 N N     . GLN A 1 446 ? 119.876 196.260 195.709 1.00 144.17 ? 451 GLN M N     1 
ATOM   3426 C CA    . GLN A 1 446 ? 119.278 194.954 195.486 1.00 144.17 ? 451 GLN M CA    1 
ATOM   3427 C C     . GLN A 1 446 ? 120.368 193.926 195.194 1.00 144.17 ? 451 GLN M C     1 
ATOM   3428 O O     . GLN A 1 446 ? 121.355 194.245 194.521 1.00 144.17 ? 451 GLN M O     1 
ATOM   3429 C CB    . GLN A 1 446 ? 118.290 195.016 194.322 1.00 144.17 ? 451 GLN M CB    1 
ATOM   3430 C CG    . GLN A 1 446 ? 117.389 193.804 194.183 1.00 144.17 ? 451 GLN M CG    1 
ATOM   3431 C CD    . GLN A 1 446 ? 116.009 194.172 193.695 1.00 144.17 ? 451 GLN M CD    1 
ATOM   3432 O OE1   . GLN A 1 446 ? 115.650 195.348 193.647 1.00 144.17 ? 451 GLN M OE1   1 
ATOM   3433 N NE2   . GLN A 1 446 ? 115.226 193.169 193.321 1.00 144.17 ? 451 GLN M NE2   1 
ATOM   3434 N N     . PRO A 1 447 ? 120.241 192.702 195.705 1.00 144.40 ? 452 PRO M N     1 
ATOM   3435 C CA    . PRO A 1 447 ? 121.230 191.666 195.385 1.00 144.40 ? 452 PRO M CA    1 
ATOM   3436 C C     . PRO A 1 447 ? 121.319 191.439 193.884 1.00 144.40 ? 452 PRO M C     1 
ATOM   3437 O O     . PRO A 1 447 ? 120.305 191.385 193.186 1.00 144.40 ? 452 PRO M O     1 
ATOM   3438 C CB    . PRO A 1 447 ? 120.696 190.427 196.111 1.00 144.40 ? 452 PRO M CB    1 
ATOM   3439 C CG    . PRO A 1 447 ? 119.840 190.968 197.199 1.00 144.40 ? 452 PRO M CG    1 
ATOM   3440 C CD    . PRO A 1 447 ? 119.234 192.229 196.670 1.00 144.40 ? 452 PRO M CD    1 
ATOM   3441 N N     . ARG A 1 448 ? 122.549 191.306 193.392 1.00 144.40 ? 453 ARG M N     1 
ATOM   3442 C CA    . ARG A 1 448 ? 122.828 191.186 191.966 1.00 144.40 ? 453 ARG M CA    1 
ATOM   3443 C C     . ARG A 1 448 ? 123.372 189.790 191.682 1.00 144.40 ? 453 ARG M C     1 
ATOM   3444 O O     . ARG A 1 448 ? 124.504 189.468 192.060 1.00 144.40 ? 453 ARG M O     1 
ATOM   3445 C CB    . ARG A 1 448 ? 123.814 192.261 191.521 1.00 144.40 ? 453 ARG M CB    1 
ATOM   3446 C CG    . ARG A 1 448 ? 123.548 193.637 192.112 1.00 144.40 ? 453 ARG M CG    1 
ATOM   3447 C CD    . ARG A 1 448 ? 124.851 194.323 192.488 1.00 144.40 ? 453 ARG M CD    1 
ATOM   3448 N NE    . ARG A 1 448 ? 124.643 195.655 193.046 1.00 144.40 ? 453 ARG M NE    1 
ATOM   3449 C CZ    . ARG A 1 448 ? 124.692 195.944 194.343 1.00 144.40 ? 453 ARG M CZ    1 
ATOM   3450 N NH1   . ARG A 1 448 ? 124.941 194.992 195.231 1.00 144.40 ? 453 ARG M NH1   1 
ATOM   3451 N NH2   . ARG A 1 448 ? 124.492 197.188 194.755 1.00 144.40 ? 453 ARG M NH2   1 
ATOM   3452 N N     . GLN A 1 449 ? 122.558 188.962 191.038 1.00 146.32 ? 454 GLN M N     1 
ATOM   3453 C CA    . GLN A 1 449 ? 122.957 187.640 190.574 1.00 146.32 ? 454 GLN M CA    1 
ATOM   3454 C C     . GLN A 1 449 ? 123.437 187.735 189.125 1.00 146.32 ? 454 GLN M C     1 
ATOM   3455 O O     . GLN A 1 449 ? 123.773 188.819 188.641 1.00 146.32 ? 454 GLN M O     1 
ATOM   3456 C CB    . GLN A 1 449 ? 121.805 186.652 190.757 1.00 146.32 ? 454 GLN M CB    1 
ATOM   3457 C CG    . GLN A 1 449 ? 121.580 186.279 192.199 1.00 146.32 ? 454 GLN M CG    1 
ATOM   3458 C CD    . GLN A 1 449 ? 122.887 186.028 192.915 1.00 146.32 ? 454 GLN M CD    1 
ATOM   3459 O OE1   . GLN A 1 449 ? 123.282 186.791 193.796 1.00 146.32 ? 454 GLN M OE1   1 
ATOM   3460 N NE2   . GLN A 1 449 ? 123.578 184.962 192.526 1.00 146.32 ? 454 GLN M NE2   1 
ATOM   3461 N N     . TYR A 1 450 ? 123.501 186.589 188.442 1.00 146.41 ? 455 TYR M N     1 
ATOM   3462 C CA    . TYR A 1 450 ? 123.989 186.490 187.070 1.00 146.41 ? 455 TYR M CA    1 
ATOM   3463 C C     . TYR A 1 450 ? 123.480 187.634 186.204 1.00 146.41 ? 455 TYR M C     1 
ATOM   3464 O O     . TYR A 1 450 ? 122.333 188.065 186.327 1.00 146.41 ? 455 TYR M O     1 
ATOM   3465 C CB    . TYR A 1 450 ? 123.552 185.155 186.461 1.00 146.41 ? 455 TYR M CB    1 
ATOM   3466 C CG    . TYR A 1 450 ? 123.582 183.990 187.423 1.00 146.41 ? 455 TYR M CG    1 
ATOM   3467 C CD1   . TYR A 1 450 ? 124.705 183.182 187.531 1.00 146.41 ? 455 TYR M CD1   1 
ATOM   3468 C CD2   . TYR A 1 450 ? 122.481 183.689 188.213 1.00 146.41 ? 455 TYR M CD2   1 
ATOM   3469 C CE1   . TYR A 1 450 ? 124.734 182.111 188.404 1.00 146.41 ? 455 TYR M CE1   1 
ATOM   3470 C CE2   . TYR A 1 450 ? 122.500 182.623 189.090 1.00 146.41 ? 455 TYR M CE2   1 
ATOM   3471 C CZ    . TYR A 1 450 ? 123.630 181.836 189.182 1.00 146.41 ? 455 TYR M CZ    1 
ATOM   3472 O OH    . TYR A 1 450 ? 123.653 180.771 190.054 1.00 146.41 ? 455 TYR M OH    1 
ATOM   3473 N N     . PHE A 1 451 ? 124.351 188.126 185.332 1.00 142.03 ? 456 PHE M N     1 
ATOM   3474 C CA    . PHE A 1 451 ? 124.064 189.267 184.480 1.00 142.03 ? 456 PHE M CA    1 
ATOM   3475 C C     . PHE A 1 451 ? 124.072 188.848 183.017 1.00 142.03 ? 456 PHE M C     1 
ATOM   3476 O O     . PHE A 1 451 ? 124.491 187.746 182.661 1.00 142.03 ? 456 PHE M O     1 
ATOM   3477 C CB    . PHE A 1 451 ? 125.078 190.399 184.710 1.00 142.03 ? 456 PHE M CB    1 
ATOM   3478 C CG    . PHE A 1 451 ? 126.475 190.067 184.269 1.00 142.03 ? 456 PHE M CG    1 
ATOM   3479 C CD1   . PHE A 1 451 ? 127.356 189.446 185.135 1.00 142.03 ? 456 PHE M CD1   1 
ATOM   3480 C CD2   . PHE A 1 451 ? 126.910 190.382 182.994 1.00 142.03 ? 456 PHE M CD2   1 
ATOM   3481 C CE1   . PHE A 1 451 ? 128.639 189.140 184.738 1.00 142.03 ? 456 PHE M CE1   1 
ATOM   3482 C CE2   . PHE A 1 451 ? 128.189 190.073 182.591 1.00 142.03 ? 456 PHE M CE2   1 
ATOM   3483 C CZ    . PHE A 1 451 ? 129.055 189.453 183.464 1.00 142.03 ? 456 PHE M CZ    1 
ATOM   3484 N N     . ILE A 1 452 ? 123.590 189.747 182.166 1.00 142.37 ? 457 ILE M N     1 
ATOM   3485 C CA    . ILE A 1 452 ? 123.665 189.590 180.719 1.00 142.37 ? 457 ILE M CA    1 
ATOM   3486 C C     . ILE A 1 452 ? 124.220 190.890 180.158 1.00 142.37 ? 457 ILE M C     1 
ATOM   3487 O O     . ILE A 1 452 ? 123.513 191.905 180.117 1.00 142.37 ? 457 ILE M O     1 
ATOM   3488 C CB    . ILE A 1 452 ? 122.308 189.263 180.087 1.00 142.37 ? 457 ILE M CB    1 
ATOM   3489 C CG1   . ILE A 1 452 ? 121.669 188.060 180.778 1.00 142.37 ? 457 ILE M CG1   1 
ATOM   3490 C CG2   . ILE A 1 452 ? 122.477 188.990 178.611 1.00 142.37 ? 457 ILE M CG2   1 
ATOM   3491 C CD1   . ILE A 1 452 ? 120.158 188.016 180.664 1.00 142.37 ? 457 ILE M CD1   1 
ATOM   3492 N N     . GLY A 1 453 ? 125.472 190.862 179.721 1.00 138.63 ? 458 GLY M N     1 
ATOM   3493 C CA    . GLY A 1 453 ? 126.138 192.068 179.283 1.00 138.63 ? 458 GLY M CA    1 
ATOM   3494 C C     . GLY A 1 453 ? 125.924 192.371 177.812 1.00 138.63 ? 458 GLY M C     1 
ATOM   3495 O O     . GLY A 1 453 ? 125.759 191.477 176.987 1.00 138.63 ? 458 GLY M O     1 
ATOM   3496 N N     . VAL A 1 454 ? 125.934 193.662 177.495 1.00 136.82 ? 459 VAL M N     1 
ATOM   3497 C CA    . VAL A 1 454 ? 125.857 194.146 176.124 1.00 136.82 ? 459 VAL M CA    1 
ATOM   3498 C C     . VAL A 1 454 ? 127.100 194.984 175.847 1.00 136.82 ? 459 VAL M C     1 
ATOM   3499 O O     . VAL A 1 454 ? 127.493 195.816 176.672 1.00 136.82 ? 459 VAL M O     1 
ATOM   3500 C CB    . VAL A 1 454 ? 124.564 194.943 175.873 1.00 136.82 ? 459 VAL M CB    1 
ATOM   3501 C CG1   . VAL A 1 454 ? 124.487 196.163 176.773 1.00 136.82 ? 459 VAL M CG1   1 
ATOM   3502 C CG2   . VAL A 1 454 ? 124.470 195.341 174.416 1.00 136.82 ? 459 VAL M CG2   1 
ATOM   3503 N N     . LEU A 1 455 ? 127.730 194.745 174.699 1.00 134.04 ? 460 LEU M N     1 
ATOM   3504 C CA    . LEU A 1 455 ? 129.061 195.258 174.409 1.00 134.04 ? 460 LEU M CA    1 
ATOM   3505 C C     . LEU A 1 455 ? 129.023 196.161 173.186 1.00 134.04 ? 460 LEU M C     1 
ATOM   3506 O O     . LEU A 1 455 ? 128.472 195.784 172.147 1.00 134.04 ? 460 LEU M O     1 
ATOM   3507 C CB    . LEU A 1 455 ? 130.038 194.098 174.194 1.00 134.04 ? 460 LEU M CB    1 
ATOM   3508 C CG    . LEU A 1 455 ? 131.541 194.367 174.232 1.00 134.04 ? 460 LEU M CG    1 
ATOM   3509 C CD1   . LEU A 1 455 ? 132.262 193.089 174.585 1.00 134.04 ? 460 LEU M CD1   1 
ATOM   3510 C CD2   . LEU A 1 455 ? 132.049 194.877 172.904 1.00 134.04 ? 460 LEU M CD2   1 
ATOM   3511 N N     . ASP A 1 456 ? 129.630 197.339 173.309 1.00 132.52 ? 461 ASP M N     1 
ATOM   3512 C CA    . ASP A 1 456 ? 129.741 198.304 172.222 1.00 132.52 ? 461 ASP M CA    1 
ATOM   3513 C C     . ASP A 1 456 ? 131.218 198.560 171.965 1.00 132.52 ? 461 ASP M C     1 
ATOM   3514 O O     . ASP A 1 456 ? 131.925 199.059 172.846 1.00 132.52 ? 461 ASP M O     1 
ATOM   3515 C CB    . ASP A 1 456 ? 129.017 199.605 172.566 1.00 132.52 ? 461 ASP M CB    1 
ATOM   3516 C CG    . ASP A 1 456 ? 128.638 200.407 171.336 1.00 132.52 ? 461 ASP M CG    1 
ATOM   3517 O OD1   . ASP A 1 456 ? 129.138 200.079 170.239 1.00 132.52 ? 461 ASP M OD1   1 
ATOM   3518 O OD2   . ASP A 1 456 ? 127.843 201.364 171.465 1.00 132.52 ? 461 ASP M OD2   1 
ATOM   3519 N N     . ILE A 1 457 ? 131.680 198.224 170.761 1.00 127.16 ? 462 ILE M N     1 
ATOM   3520 C CA    . ILE A 1 457 ? 133.100 198.236 170.440 1.00 127.16 ? 462 ILE M CA    1 
ATOM   3521 C C     . ILE A 1 457 ? 133.297 198.883 169.076 1.00 127.16 ? 462 ILE M C     1 
ATOM   3522 O O     . ILE A 1 457 ? 132.373 198.979 168.268 1.00 127.16 ? 462 ILE M O     1 
ATOM   3523 C CB    . ILE A 1 457 ? 133.700 196.810 170.456 1.00 127.16 ? 462 ILE M CB    1 
ATOM   3524 C CG1   . ILE A 1 457 ? 135.180 196.847 170.817 1.00 127.16 ? 462 ILE M CG1   1 
ATOM   3525 C CG2   . ILE A 1 457 ? 133.492 196.110 169.126 1.00 127.16 ? 462 ILE M CG2   1 
ATOM   3526 C CD1   . ILE A 1 457 ? 135.438 197.316 172.216 1.00 127.16 ? 462 ILE M CD1   1 
ATOM   3527 N N     . ALA A 1 458 ? 134.521 199.341 168.832 1.00 122.93 ? 463 ALA M N     1 
ATOM   3528 C CA    . ALA A 1 458 ? 134.859 199.895 167.532 1.00 122.93 ? 463 ALA M CA    1 
ATOM   3529 C C     . ALA A 1 458 ? 134.816 198.811 166.457 1.00 122.93 ? 463 ALA M C     1 
ATOM   3530 O O     . ALA A 1 458 ? 134.806 197.611 166.740 1.00 122.93 ? 463 ALA M O     1 
ATOM   3531 C CB    . ALA A 1 458 ? 136.240 200.543 167.567 1.00 122.93 ? 463 ALA M CB    1 
ATOM   3532 N N     . GLY A 1 459 ? 134.786 199.253 165.202 1.00 120.36 ? 464 GLY M N     1 
ATOM   3533 C CA    . GLY A 1 459 ? 134.653 198.355 164.078 1.00 120.36 ? 464 GLY M CA    1 
ATOM   3534 C C     . GLY A 1 459 ? 135.967 198.104 163.355 1.00 120.36 ? 464 GLY M C     1 
ATOM   3535 O O     . GLY A 1 459 ? 136.959 198.798 163.536 1.00 120.36 ? 464 GLY M O     1 
ATOM   3536 N N     . PHE A 1 460 ? 135.941 197.095 162.491 1.00 119.19 ? 465 PHE M N     1 
ATOM   3537 C CA    . PHE A 1 460 ? 137.130 196.706 161.749 1.00 119.19 ? 465 PHE M CA    1 
ATOM   3538 C C     . PHE A 1 460 ? 137.440 197.744 160.684 1.00 119.19 ? 465 PHE M C     1 
ATOM   3539 O O     . PHE A 1 460 ? 137.347 197.464 159.486 1.00 119.19 ? 465 PHE M O     1 
ATOM   3540 C CB    . PHE A 1 460 ? 136.926 195.337 161.112 1.00 119.19 ? 465 PHE M CB    1 
ATOM   3541 C CG    . PHE A 1 460 ? 138.193 194.628 160.814 1.00 119.19 ? 465 PHE M CG    1 
ATOM   3542 C CD1   . PHE A 1 460 ? 138.611 193.586 161.609 1.00 119.19 ? 465 PHE M CD1   1 
ATOM   3543 C CD2   . PHE A 1 460 ? 138.978 195.012 159.748 1.00 119.19 ? 465 PHE M CD2   1 
ATOM   3544 C CE1   . PHE A 1 460 ? 139.782 192.936 161.342 1.00 119.19 ? 465 PHE M CE1   1 
ATOM   3545 C CE2   . PHE A 1 460 ? 140.150 194.367 159.477 1.00 119.19 ? 465 PHE M CE2   1 
ATOM   3546 C CZ    . PHE A 1 460 ? 140.553 193.331 160.275 1.00 119.19 ? 465 PHE M CZ    1 
ATOM   3547 N N     . GLU A 1 461 ? 137.823 198.939 161.110 1.00 115.85 ? 466 GLU M N     1 
ATOM   3548 C CA    . GLU A 1 461 ? 137.899 200.061 160.192 1.00 115.85 ? 466 GLU M CA    1 
ATOM   3549 C C     . GLU A 1 461 ? 139.023 199.877 159.185 1.00 115.85 ? 466 GLU M C     1 
ATOM   3550 O O     . GLU A 1 461 ? 140.135 199.475 159.533 1.00 115.85 ? 466 GLU M O     1 
ATOM   3551 C CB    . GLU A 1 461 ? 138.093 201.359 160.968 1.00 115.85 ? 466 GLU M CB    1 
ATOM   3552 C CG    . GLU A 1 461 ? 139.100 201.275 162.097 1.00 115.85 ? 466 GLU M CG    1 
ATOM   3553 C CD    . GLU A 1 461 ? 139.096 202.527 162.948 1.00 115.85 ? 466 GLU M CD    1 
ATOM   3554 O OE1   . GLU A 1 461 ? 138.481 203.524 162.519 1.00 115.85 ? 466 GLU M OE1   1 
ATOM   3555 O OE2   . GLU A 1 461 ? 139.700 202.520 164.040 1.00 115.85 ? 466 GLU M OE2   1 
ATOM   3556 N N     . ILE A 1 462 ? 138.717 200.169 157.927 1.00 114.59 ? 467 ILE M N     1 
ATOM   3557 C CA    . ILE A 1 462 ? 139.695 200.190 156.852 1.00 114.59 ? 467 ILE M CA    1 
ATOM   3558 C C     . ILE A 1 462 ? 139.685 201.582 156.246 1.00 114.59 ? 467 ILE M C     1 
ATOM   3559 O O     . ILE A 1 462 ? 138.650 202.252 156.197 1.00 114.59 ? 467 ILE M O     1 
ATOM   3560 C CB    . ILE A 1 462 ? 139.408 199.126 155.773 1.00 114.59 ? 467 ILE M CB    1 
ATOM   3561 C CG1   . ILE A 1 462 ? 139.057 197.790 156.420 1.00 114.59 ? 467 ILE M CG1   1 
ATOM   3562 C CG2   . ILE A 1 462 ? 140.605 198.967 154.848 1.00 114.59 ? 467 ILE M CG2   1 
ATOM   3563 C CD1   . ILE A 1 462 ? 140.182 197.192 157.214 1.00 114.59 ? 467 ILE M CD1   1 
ATOM   3564 N N     . PHE A 1 463 ? 140.854 202.026 155.807 1.00 113.70 ? 468 PHE M N     1 
ATOM   3565 C CA    . PHE A 1 463 ? 141.002 203.323 155.166 1.00 113.70 ? 468 PHE M CA    1 
ATOM   3566 C C     . PHE A 1 463 ? 142.028 203.162 154.055 1.00 113.70 ? 468 PHE M C     1 
ATOM   3567 O O     . PHE A 1 463 ? 142.320 202.051 153.602 1.00 113.70 ? 468 PHE M O     1 
ATOM   3568 C CB    . PHE A 1 463 ? 141.398 204.401 156.183 1.00 113.70 ? 468 PHE M CB    1 
ATOM   3569 C CG    . PHE A 1 463 ? 140.356 204.665 157.226 1.00 113.70 ? 468 PHE M CG    1 
ATOM   3570 C CD1   . PHE A 1 463 ? 139.397 205.638 157.030 1.00 113.70 ? 468 PHE M CD1   1 
ATOM   3571 C CD2   . PHE A 1 463 ? 140.346 203.951 158.409 1.00 113.70 ? 468 PHE M CD2   1 
ATOM   3572 C CE1   . PHE A 1 463 ? 138.442 205.888 157.990 1.00 113.70 ? 468 PHE M CE1   1 
ATOM   3573 C CE2   . PHE A 1 463 ? 139.393 204.196 159.373 1.00 113.70 ? 468 PHE M CE2   1 
ATOM   3574 C CZ    . PHE A 1 463 ? 138.439 205.162 159.163 1.00 113.70 ? 468 PHE M CZ    1 
ATOM   3575 N N     . ASP A 1 464 ? 142.561 204.283 153.585 1.00 114.39 ? 469 ASP M N     1 
ATOM   3576 C CA    . ASP A 1 464 ? 143.706 204.285 152.692 1.00 114.39 ? 469 ASP M CA    1 
ATOM   3577 C C     . ASP A 1 464 ? 144.991 204.740 153.367 1.00 114.39 ? 469 ASP M C     1 
ATOM   3578 O O     . ASP A 1 464 ? 146.056 204.666 152.746 1.00 114.39 ? 469 ASP M O     1 
ATOM   3579 C CB    . ASP A 1 464 ? 143.416 205.174 151.479 1.00 114.39 ? 469 ASP M CB    1 
ATOM   3580 C CG    . ASP A 1 464 ? 142.991 206.561 151.877 1.00 114.39 ? 469 ASP M CG    1 
ATOM   3581 O OD1   . ASP A 1 464 ? 142.876 206.815 153.095 1.00 114.39 ? 469 ASP M OD1   1 
ATOM   3582 O OD2   . ASP A 1 464 ? 142.757 207.390 150.974 1.00 114.39 ? 469 ASP M OD2   1 
ATOM   3583 N N     . PHE A 1 465 ? 144.918 205.208 154.610 1.00 109.18 ? 470 PHE M N     1 
ATOM   3584 C CA    . PHE A 1 465 ? 146.074 205.586 155.415 1.00 109.18 ? 470 PHE M CA    1 
ATOM   3585 C C     . PHE A 1 465 ? 145.950 204.995 156.809 1.00 109.18 ? 470 PHE M C     1 
ATOM   3586 O O     . PHE A 1 465 ? 146.021 205.693 157.820 1.00 109.18 ? 470 PHE M O     1 
ATOM   3587 C CB    . PHE A 1 465 ? 146.246 207.096 155.491 1.00 109.18 ? 470 PHE M CB    1 
ATOM   3588 C CG    . PHE A 1 465 ? 147.583 207.522 156.025 1.00 109.18 ? 470 PHE M CG    1 
ATOM   3589 C CD1   . PHE A 1 465 ? 148.724 207.368 155.262 1.00 109.18 ? 470 PHE M CD1   1 
ATOM   3590 C CD2   . PHE A 1 465 ? 147.700 208.077 157.286 1.00 109.18 ? 470 PHE M CD2   1 
ATOM   3591 C CE1   . PHE A 1 465 ? 149.951 207.757 155.746 1.00 109.18 ? 470 PHE M CE1   1 
ATOM   3592 C CE2   . PHE A 1 465 ? 148.928 208.463 157.774 1.00 109.18 ? 470 PHE M CE2   1 
ATOM   3593 C CZ    . PHE A 1 465 ? 150.053 208.306 157.001 1.00 109.18 ? 470 PHE M CZ    1 
ATOM   3594 N N     . ASN A 1 466 ? 145.698 203.691 156.870 1.00 107.57 ? 471 ASN M N     1 
ATOM   3595 C CA    . ASN A 1 466 ? 145.696 202.982 158.142 1.00 107.57 ? 471 ASN M CA    1 
ATOM   3596 C C     . ASN A 1 466 ? 146.987 203.252 158.904 1.00 107.57 ? 471 ASN M C     1 
ATOM   3597 O O     . ASN A 1 466 ? 148.052 203.450 158.315 1.00 107.57 ? 471 ASN M O     1 
ATOM   3598 C CB    . ASN A 1 466 ? 145.537 201.488 157.894 1.00 107.57 ? 471 ASN M CB    1 
ATOM   3599 C CG    . ASN A 1 466 ? 144.629 201.199 156.736 1.00 107.57 ? 471 ASN M CG    1 
ATOM   3600 O OD1   . ASN A 1 466 ? 143.493 201.657 156.701 1.00 107.57 ? 471 ASN M OD1   1 
ATOM   3601 N ND2   . ASN A 1 466 ? 145.131 200.458 155.760 1.00 107.57 ? 471 ASN M ND2   1 
ATOM   3602 N N     . SER A 1 467 ? 146.894 203.253 160.226 1.00 102.21 ? 472 SER M N     1 
ATOM   3603 C CA    . SER A 1 467 ? 148.030 203.611 161.061 1.00 102.21 ? 472 SER M CA    1 
ATOM   3604 C C     . SER A 1 467 ? 148.037 202.715 162.293 1.00 102.21 ? 472 SER M C     1 
ATOM   3605 O O     . SER A 1 467 ? 147.388 201.665 162.339 1.00 102.21 ? 472 SER M O     1 
ATOM   3606 C CB    . SER A 1 467 ? 147.990 205.098 161.428 1.00 102.21 ? 472 SER M CB    1 
ATOM   3607 O OG    . SER A 1 467 ? 148.837 205.358 162.531 1.00 102.21 ? 472 SER M OG    1 
ATOM   3608 N N     . PHE A 1 468 ? 148.805 203.136 163.295 1.00 98.10  ? 473 PHE M N     1 
ATOM   3609 C CA    . PHE A 1 468 ? 148.992 202.342 164.502 1.00 98.10  ? 473 PHE M CA    1 
ATOM   3610 C C     . PHE A 1 468 ? 147.668 202.097 165.213 1.00 98.10  ? 473 PHE M C     1 
ATOM   3611 O O     . PHE A 1 468 ? 147.378 200.977 165.651 1.00 98.10  ? 473 PHE M O     1 
ATOM   3612 C CB    . PHE A 1 468 ? 149.982 203.061 165.415 1.00 98.10  ? 473 PHE M CB    1 
ATOM   3613 C CG    . PHE A 1 468 ? 150.298 202.326 166.668 1.00 98.10  ? 473 PHE M CG    1 
ATOM   3614 C CD1   . PHE A 1 468 ? 150.759 201.031 166.623 1.00 98.10  ? 473 PHE M CD1   1 
ATOM   3615 C CD2   . PHE A 1 468 ? 150.163 202.940 167.892 1.00 98.10  ? 473 PHE M CD2   1 
ATOM   3616 C CE1   . PHE A 1 468 ? 151.058 200.359 167.771 1.00 98.10  ? 473 PHE M CE1   1 
ATOM   3617 C CE2   . PHE A 1 468 ? 150.462 202.269 169.042 1.00 98.10  ? 473 PHE M CE2   1 
ATOM   3618 C CZ    . PHE A 1 468 ? 150.910 200.977 168.982 1.00 98.10  ? 473 PHE M CZ    1 
ATOM   3619 N N     . GLU A 1 469 ? 146.854 203.142 165.340 1.00 102.41 ? 474 GLU M N     1 
ATOM   3620 C CA    . GLU A 1 469 ? 145.584 203.015 166.041 1.00 102.41 ? 474 GLU M CA    1 
ATOM   3621 C C     . GLU A 1 469 ? 144.657 202.053 165.318 1.00 102.41 ? 474 GLU M C     1 
ATOM   3622 O O     . GLU A 1 469 ? 143.976 201.237 165.951 1.00 102.41 ? 474 GLU M O     1 
ATOM   3623 C CB    . GLU A 1 469 ? 144.931 204.387 166.174 1.00 102.41 ? 474 GLU M CB    1 
ATOM   3624 C CG    . GLU A 1 469 ? 145.877 205.491 166.622 1.00 102.41 ? 474 GLU M CG    1 
ATOM   3625 C CD    . GLU A 1 469 ? 146.732 206.036 165.493 1.00 102.41 ? 474 GLU M CD    1 
ATOM   3626 O OE1   . GLU A 1 469 ? 146.957 205.304 164.506 1.00 102.41 ? 474 GLU M OE1   1 
ATOM   3627 O OE2   . GLU A 1 469 ? 147.180 207.196 165.591 1.00 102.41 ? 474 GLU M OE2   1 
ATOM   3628 N N     . GLN A 1 470 ? 144.614 202.138 163.990 1.00 104.55 ? 475 GLN M N     1 
ATOM   3629 C CA    . GLN A 1 470 ? 143.787 201.214 163.229 1.00 104.55 ? 475 GLN M CA    1 
ATOM   3630 C C     . GLN A 1 470 ? 144.307 199.793 163.354 1.00 104.55 ? 475 GLN M C     1 
ATOM   3631 O O     . GLN A 1 470 ? 143.521 198.841 163.377 1.00 104.55 ? 475 GLN M O     1 
ATOM   3632 C CB    . GLN A 1 470 ? 143.715 201.648 161.768 1.00 104.55 ? 475 GLN M CB    1 
ATOM   3633 C CG    . GLN A 1 470 ? 142.938 202.934 161.566 1.00 104.55 ? 475 GLN M CG    1 
ATOM   3634 C CD    . GLN A 1 470 ? 143.774 204.163 161.837 1.00 104.55 ? 475 GLN M CD    1 
ATOM   3635 O OE1   . GLN A 1 470 ? 144.994 204.097 161.832 1.00 104.55 ? 475 GLN M OE1   1 
ATOM   3636 N NE2   . GLN A 1 470 ? 143.123 205.288 162.085 1.00 104.55 ? 475 GLN M NE2   1 
ATOM   3637 N N     . LEU A 1 471 ? 145.626 199.628 163.456 1.00 102.26 ? 476 LEU M N     1 
ATOM   3638 C CA    . LEU A 1 471 ? 146.172 198.298 163.700 1.00 102.26 ? 476 LEU M CA    1 
ATOM   3639 C C     . LEU A 1 471 ? 145.711 197.758 165.045 1.00 102.26 ? 476 LEU M C     1 
ATOM   3640 O O     . LEU A 1 471 ? 145.353 196.582 165.159 1.00 102.26 ? 476 LEU M O     1 
ATOM   3641 C CB    . LEU A 1 471 ? 147.695 198.331 163.631 1.00 102.26 ? 476 LEU M CB    1 
ATOM   3642 C CG    . LEU A 1 471 ? 148.385 197.063 164.127 1.00 102.26 ? 476 LEU M CG    1 
ATOM   3643 C CD1   . LEU A 1 471 ? 147.900 195.837 163.378 1.00 102.26 ? 476 LEU M CD1   1 
ATOM   3644 C CD2   . LEU A 1 471 ? 149.877 197.202 163.985 1.00 102.26 ? 476 LEU M CD2   1 
ATOM   3645 N N     . CYS A 1 472 ? 145.711 198.604 166.074 1.00 104.71 ? 477 CYS M N     1 
ATOM   3646 C CA    . CYS A 1 472 ? 145.229 198.168 167.382 1.00 104.71 ? 477 CYS M CA    1 
ATOM   3647 C C     . CYS A 1 472 ? 143.761 197.767 167.316 1.00 104.71 ? 477 CYS M C     1 
ATOM   3648 O O     . CYS A 1 472 ? 143.361 196.724 167.856 1.00 104.71 ? 477 CYS M O     1 
ATOM   3649 C CB    . CYS A 1 472 ? 145.428 199.279 168.409 1.00 104.71 ? 477 CYS M CB    1 
ATOM   3650 S SG    . CYS A 1 472 ? 147.070 199.345 169.149 1.00 104.71 ? 477 CYS M SG    1 
ATOM   3651 N N     . ILE A 1 473 ? 142.946 198.588 166.652 1.00 109.16 ? 478 ILE M N     1 
ATOM   3652 C CA    . ILE A 1 473 ? 141.521 198.298 166.518 1.00 109.16 ? 478 ILE M CA    1 
ATOM   3653 C C     . ILE A 1 473 ? 141.316 196.967 165.810 1.00 109.16 ? 478 ILE M C     1 
ATOM   3654 O O     . ILE A 1 473 ? 140.520 196.124 166.242 1.00 109.16 ? 478 ILE M O     1 
ATOM   3655 C CB    . ILE A 1 473 ? 140.812 199.439 165.769 1.00 109.16 ? 478 ILE M CB    1 
ATOM   3656 C CG1   . ILE A 1 473 ? 140.880 200.738 166.566 1.00 109.16 ? 478 ILE M CG1   1 
ATOM   3657 C CG2   . ILE A 1 473 ? 139.381 199.075 165.517 1.00 109.16 ? 478 ILE M CG2   1 
ATOM   3658 C CD1   . ILE A 1 473 ? 140.092 200.708 167.841 1.00 109.16 ? 478 ILE M CD1   1 
ATOM   3659 N N     . ASN A 1 474 ? 142.026 196.765 164.703 1.00 110.48 ? 479 ASN M N     1 
ATOM   3660 C CA    . ASN A 1 474 ? 141.870 195.534 163.947 1.00 110.48 ? 479 ASN M CA    1 
ATOM   3661 C C     . ASN A 1 474 ? 142.363 194.334 164.732 1.00 110.48 ? 479 ASN M C     1 
ATOM   3662 O O     . ASN A 1 474 ? 141.813 193.243 164.586 1.00 110.48 ? 479 ASN M O     1 
ATOM   3663 C CB    . ASN A 1 474 ? 142.607 195.638 162.620 1.00 110.48 ? 479 ASN M CB    1 
ATOM   3664 C CG    . ASN A 1 474 ? 142.049 196.718 161.744 1.00 110.48 ? 479 ASN M CG    1 
ATOM   3665 O OD1   . ASN A 1 474 ? 141.344 197.605 162.214 1.00 110.48 ? 479 ASN M OD1   1 
ATOM   3666 N ND2   . ASN A 1 474 ? 142.354 196.653 160.460 1.00 110.48 ? 479 ASN M ND2   1 
ATOM   3667 N N     . PHE A 1 475 ? 143.387 194.512 165.566 1.00 109.29 ? 480 PHE M N     1 
ATOM   3668 C CA    . PHE A 1 475 ? 143.845 193.419 166.414 1.00 109.29 ? 480 PHE M CA    1 
ATOM   3669 C C     . PHE A 1 475 ? 142.762 193.019 167.406 1.00 109.29 ? 480 PHE M C     1 
ATOM   3670 O O     . PHE A 1 475 ? 142.500 191.824 167.625 1.00 109.29 ? 480 PHE M O     1 
ATOM   3671 C CB    . PHE A 1 475 ? 145.129 193.833 167.135 1.00 109.29 ? 480 PHE M CB    1 
ATOM   3672 C CG    . PHE A 1 475 ? 145.607 192.829 168.134 1.00 109.29 ? 480 PHE M CG    1 
ATOM   3673 C CD1   . PHE A 1 475 ? 145.857 191.526 167.755 1.00 109.29 ? 480 PHE M CD1   1 
ATOM   3674 C CD2   . PHE A 1 475 ? 145.801 193.187 169.449 1.00 109.29 ? 480 PHE M CD2   1 
ATOM   3675 C CE1   . PHE A 1 475 ? 146.287 190.602 168.672 1.00 109.29 ? 480 PHE M CE1   1 
ATOM   3676 C CE2   . PHE A 1 475 ? 146.232 192.266 170.368 1.00 109.29 ? 480 PHE M CE2   1 
ATOM   3677 C CZ    . PHE A 1 475 ? 146.476 190.972 169.980 1.00 109.29 ? 480 PHE M CZ    1 
ATOM   3678 N N     . THR A 1 476 ? 142.114 194.014 168.014 1.00 111.91 ? 481 THR M N     1 
ATOM   3679 C CA    . THR A 1 476 ? 140.998 193.726 168.911 1.00 111.91 ? 481 THR M CA    1 
ATOM   3680 C C     . THR A 1 476 ? 139.901 192.962 168.183 1.00 111.91 ? 481 THR M C     1 
ATOM   3681 O O     . THR A 1 476 ? 139.413 191.929 168.663 1.00 111.91 ? 481 THR M O     1 
ATOM   3682 C CB    . THR A 1 476 ? 140.444 195.023 169.491 1.00 111.91 ? 481 THR M CB    1 
ATOM   3683 O OG1   . THR A 1 476 ? 140.313 195.991 168.448 1.00 111.91 ? 481 THR M OG1   1 
ATOM   3684 C CG2   . THR A 1 476 ? 141.378 195.568 170.533 1.00 111.91 ? 481 THR M CG2   1 
ATOM   3685 N N     . ASN A 1 477 ? 139.506 193.460 167.012 1.00 117.74 ? 482 ASN M N     1 
ATOM   3686 C CA    . ASN A 1 477 ? 138.435 192.815 166.263 1.00 117.74 ? 482 ASN M CA    1 
ATOM   3687 C C     . ASN A 1 477 ? 138.839 191.427 165.795 1.00 117.74 ? 482 ASN M C     1 
ATOM   3688 O O     . ASN A 1 477 ? 137.985 190.551 165.653 1.00 117.74 ? 482 ASN M O     1 
ATOM   3689 C CB    . ASN A 1 477 ? 138.028 193.694 165.088 1.00 117.74 ? 482 ASN M CB    1 
ATOM   3690 C CG    . ASN A 1 477 ? 137.383 194.981 165.536 1.00 117.74 ? 482 ASN M CG    1 
ATOM   3691 O OD1   . ASN A 1 477 ? 136.546 194.984 166.434 1.00 117.74 ? 482 ASN M OD1   1 
ATOM   3692 N ND2   . ASN A 1 477 ? 137.778 196.086 164.927 1.00 117.74 ? 482 ASN M ND2   1 
ATOM   3693 N N     . GLU A 1 478 ? 140.130 191.202 165.574 1.00 119.18 ? 483 GLU M N     1 
ATOM   3694 C CA    . GLU A 1 478 ? 140.614 189.860 165.287 1.00 119.18 ? 483 GLU M CA    1 
ATOM   3695 C C     . GLU A 1 478 ? 140.381 188.933 166.465 1.00 119.18 ? 483 GLU M C     1 
ATOM   3696 O O     . GLU A 1 478 ? 139.903 187.805 166.291 1.00 119.18 ? 483 GLU M O     1 
ATOM   3697 C CB    . GLU A 1 478 ? 142.100 189.909 164.943 1.00 119.18 ? 483 GLU M CB    1 
ATOM   3698 C CG    . GLU A 1 478 ? 142.403 190.354 163.542 1.00 119.18 ? 483 GLU M CG    1 
ATOM   3699 C CD    . GLU A 1 478 ? 142.095 189.267 162.548 1.00 119.18 ? 483 GLU M CD    1 
ATOM   3700 O OE1   . GLU A 1 478 ? 142.248 188.085 162.918 1.00 119.18 ? 483 GLU M OE1   1 
ATOM   3701 O OE2   . GLU A 1 478 ? 141.702 189.581 161.409 1.00 119.18 ? 483 GLU M OE2   1 
ATOM   3702 N N     . LYS A 1 479 ? 140.730 189.380 167.670 1.00 118.73 ? 484 LYS M N     1 
ATOM   3703 C CA    . LYS A 1 479 ? 140.470 188.542 168.835 1.00 118.73 ? 484 LYS M CA    1 
ATOM   3704 C C     . LYS A 1 479 ? 138.984 188.229 168.947 1.00 118.73 ? 484 LYS M C     1 
ATOM   3705 O O     . LYS A 1 479 ? 138.597 187.076 169.183 1.00 118.73 ? 484 LYS M O     1 
ATOM   3706 C CB    . LYS A 1 479 ? 140.985 189.214 170.104 1.00 118.73 ? 484 LYS M CB    1 
ATOM   3707 C CG    . LYS A 1 479 ? 142.492 189.364 170.136 1.00 118.73 ? 484 LYS M CG    1 
ATOM   3708 C CD    . LYS A 1 479 ? 143.197 188.089 170.557 1.00 118.73 ? 484 LYS M CD    1 
ATOM   3709 C CE    . LYS A 1 479 ? 143.283 187.974 172.066 1.00 118.73 ? 484 LYS M CE    1 
ATOM   3710 N NZ    . LYS A 1 479 ? 143.999 186.739 172.489 1.00 118.73 ? 484 LYS M NZ    1 
ATOM   3711 N N     . LEU A 1 480 ? 138.136 189.240 168.741 1.00 124.06 ? 485 LEU M N     1 
ATOM   3712 C CA    . LEU A 1 480 ? 136.693 189.027 168.836 1.00 124.06 ? 485 LEU M CA    1 
ATOM   3713 C C     . LEU A 1 480 ? 136.200 188.031 167.791 1.00 124.06 ? 485 LEU M C     1 
ATOM   3714 O O     . LEU A 1 480 ? 135.419 187.124 168.106 1.00 124.06 ? 485 LEU M O     1 
ATOM   3715 C CB    . LEU A 1 480 ? 135.953 190.351 168.682 1.00 124.06 ? 485 LEU M CB    1 
ATOM   3716 C CG    . LEU A 1 480 ? 136.081 191.333 169.838 1.00 124.06 ? 485 LEU M CG    1 
ATOM   3717 C CD1   . LEU A 1 480 ? 135.244 192.563 169.567 1.00 124.06 ? 485 LEU M CD1   1 
ATOM   3718 C CD2   . LEU A 1 480 ? 135.659 190.662 171.127 1.00 124.06 ? 485 LEU M CD2   1 
ATOM   3719 N N     . GLN A 1 481 ? 136.623 188.200 166.537 1.00 129.79 ? 486 GLN M N     1 
ATOM   3720 C CA    . GLN A 1 481 ? 136.144 187.330 165.473 1.00 129.79 ? 486 GLN M CA    1 
ATOM   3721 C C     . GLN A 1 481 ? 136.621 185.902 165.677 1.00 129.79 ? 486 GLN M C     1 
ATOM   3722 O O     . GLN A 1 481 ? 135.871 184.953 165.435 1.00 129.79 ? 486 GLN M O     1 
ATOM   3723 C CB    . GLN A 1 481 ? 136.593 187.862 164.114 1.00 129.79 ? 486 GLN M CB    1 
ATOM   3724 C CG    . GLN A 1 481 ? 136.355 186.904 162.953 1.00 129.79 ? 486 GLN M CG    1 
ATOM   3725 C CD    . GLN A 1 481 ? 134.931 186.380 162.893 1.00 129.79 ? 486 GLN M CD    1 
ATOM   3726 O OE1   . GLN A 1 481 ? 133.973 187.149 162.851 1.00 129.79 ? 486 GLN M OE1   1 
ATOM   3727 N NE2   . GLN A 1 481 ? 134.787 185.063 162.901 1.00 129.79 ? 486 GLN M NE2   1 
ATOM   3728 N N     . GLN A 1 482 ? 137.860 185.725 166.133 1.00 131.90 ? 487 GLN M N     1 
ATOM   3729 C CA    . GLN A 1 482 ? 138.336 184.381 166.433 1.00 131.90 ? 487 GLN M CA    1 
ATOM   3730 C C     . GLN A 1 482 ? 137.545 183.771 167.580 1.00 131.90 ? 487 GLN M C     1 
ATOM   3731 O O     . GLN A 1 482 ? 137.245 182.570 167.572 1.00 131.90 ? 487 GLN M O     1 
ATOM   3732 C CB    . GLN A 1 482 ? 139.829 184.419 166.753 1.00 131.90 ? 487 GLN M CB    1 
ATOM   3733 C CG    . GLN A 1 482 ? 140.411 183.091 167.182 1.00 131.90 ? 487 GLN M CG    1 
ATOM   3734 C CD    . GLN A 1 482 ? 140.496 182.958 168.685 1.00 131.90 ? 487 GLN M CD    1 
ATOM   3735 O OE1   . GLN A 1 482 ? 141.267 183.660 169.336 1.00 131.90 ? 487 GLN M OE1   1 
ATOM   3736 N NE2   . GLN A 1 482 ? 139.700 182.056 169.246 1.00 131.90 ? 487 GLN M NE2   1 
ATOM   3737 N N     . PHE A 1 483 ? 137.181 184.590 168.567 1.00 135.05 ? 488 PHE M N     1 
ATOM   3738 C CA    . PHE A 1 483 ? 136.360 184.102 169.668 1.00 135.05 ? 488 PHE M CA    1 
ATOM   3739 C C     . PHE A 1 483 ? 135.008 183.609 169.172 1.00 135.05 ? 488 PHE M C     1 
ATOM   3740 O O     . PHE A 1 483 ? 134.568 182.507 169.522 1.00 135.05 ? 488 PHE M O     1 
ATOM   3741 C CB    . PHE A 1 483 ? 136.180 185.207 170.702 1.00 135.05 ? 488 PHE M CB    1 
ATOM   3742 C CG    . PHE A 1 483 ? 135.006 185.004 171.604 1.00 135.05 ? 488 PHE M CG    1 
ATOM   3743 C CD1   . PHE A 1 483 ? 134.900 183.868 172.384 1.00 135.05 ? 488 PHE M CD1   1 
ATOM   3744 C CD2   . PHE A 1 483 ? 134.012 185.959 171.682 1.00 135.05 ? 488 PHE M CD2   1 
ATOM   3745 C CE1   . PHE A 1 483 ? 133.823 183.687 173.218 1.00 135.05 ? 488 PHE M CE1   1 
ATOM   3746 C CE2   . PHE A 1 483 ? 132.933 185.785 172.516 1.00 135.05 ? 488 PHE M CE2   1 
ATOM   3747 C CZ    . PHE A 1 483 ? 132.838 184.648 173.285 1.00 135.05 ? 488 PHE M CZ    1 
ATOM   3748 N N     . PHE A 1 484 ? 134.329 184.424 168.362 1.00 142.14 ? 489 PHE M N     1 
ATOM   3749 C CA    . PHE A 1 484 ? 133.046 184.002 167.806 1.00 142.14 ? 489 PHE M CA    1 
ATOM   3750 C C     . PHE A 1 484 ? 133.204 182.753 166.952 1.00 142.14 ? 489 PHE M C     1 
ATOM   3751 O O     . PHE A 1 484 ? 132.339 181.873 166.958 1.00 142.14 ? 489 PHE M O     1 
ATOM   3752 C CB    . PHE A 1 484 ? 132.414 185.113 166.969 1.00 142.14 ? 489 PHE M CB    1 
ATOM   3753 C CG    . PHE A 1 484 ? 131.492 184.593 165.903 1.00 142.14 ? 489 PHE M CG    1 
ATOM   3754 C CD1   . PHE A 1 484 ? 130.233 184.125 166.231 1.00 142.14 ? 489 PHE M CD1   1 
ATOM   3755 C CD2   . PHE A 1 484 ? 131.896 184.535 164.582 1.00 142.14 ? 489 PHE M CD2   1 
ATOM   3756 C CE1   . PHE A 1 484 ? 129.389 183.624 165.263 1.00 142.14 ? 489 PHE M CE1   1 
ATOM   3757 C CE2   . PHE A 1 484 ? 131.055 184.035 163.608 1.00 142.14 ? 489 PHE M CE2   1 
ATOM   3758 C CZ    . PHE A 1 484 ? 129.800 183.579 163.951 1.00 142.14 ? 489 PHE M CZ    1 
ATOM   3759 N N     . ASN A 1 485 ? 134.285 182.679 166.181 1.00 142.68 ? 490 ASN M N     1 
ATOM   3760 C CA    . ASN A 1 485 ? 134.481 181.539 165.302 1.00 142.68 ? 490 ASN M CA    1 
ATOM   3761 C C     . ASN A 1 485 ? 134.628 180.258 166.105 1.00 142.68 ? 490 ASN M C     1 
ATOM   3762 O O     . ASN A 1 485 ? 134.024 179.234 165.771 1.00 142.68 ? 490 ASN M O     1 
ATOM   3763 C CB    . ASN A 1 485 ? 135.701 181.775 164.420 1.00 142.68 ? 490 ASN M CB    1 
ATOM   3764 C CG    . ASN A 1 485 ? 135.738 180.857 163.233 1.00 142.68 ? 490 ASN M CG    1 
ATOM   3765 O OD1   . ASN A 1 485 ? 134.796 180.112 162.981 1.00 142.68 ? 490 ASN M OD1   1 
ATOM   3766 N ND2   . ASN A 1 485 ? 136.830 180.900 162.489 1.00 142.68 ? 490 ASN M ND2   1 
ATOM   3767 N N     . HIS A 1 486 ? 135.410 180.301 167.185 1.00 145.14 ? 491 HIS M N     1 
ATOM   3768 C CA    . HIS A 1 486 ? 135.522 179.129 168.044 1.00 145.14 ? 491 HIS M CA    1 
ATOM   3769 C C     . HIS A 1 486 ? 134.192 178.807 168.710 1.00 145.14 ? 491 HIS M C     1 
ATOM   3770 O O     . HIS A 1 486 ? 133.836 177.631 168.881 1.00 145.14 ? 491 HIS M O     1 
ATOM   3771 C CB    . HIS A 1 486 ? 136.598 179.348 169.099 1.00 145.14 ? 491 HIS M CB    1 
ATOM   3772 C CG    . HIS A 1 486 ? 136.480 178.424 170.265 1.00 145.14 ? 491 HIS M CG    1 
ATOM   3773 N ND1   . HIS A 1 486 ? 136.176 178.864 171.533 1.00 145.14 ? 491 HIS M ND1   1 
ATOM   3774 C CD2   . HIS A 1 486 ? 136.608 177.080 170.352 1.00 145.14 ? 491 HIS M CD2   1 
ATOM   3775 C CE1   . HIS A 1 486 ? 136.132 177.832 172.355 1.00 145.14 ? 491 HIS M CE1   1 
ATOM   3776 N NE2   . HIS A 1 486 ? 136.390 176.737 171.663 1.00 145.14 ? 491 HIS M NE2   1 
ATOM   3777 N N     . HIS A 1 487 ? 133.448 179.841 169.105 1.00 147.78 ? 492 HIS M N     1 
ATOM   3778 C CA    . HIS A 1 487 ? 132.126 179.633 169.686 1.00 147.78 ? 492 HIS M CA    1 
ATOM   3779 C C     . HIS A 1 487 ? 131.222 178.871 168.727 1.00 147.78 ? 492 HIS M C     1 
ATOM   3780 O O     . HIS A 1 487 ? 130.621 177.854 169.091 1.00 147.78 ? 492 HIS M O     1 
ATOM   3781 C CB    . HIS A 1 487 ? 131.520 180.988 170.055 1.00 147.78 ? 492 HIS M CB    1 
ATOM   3782 C CG    . HIS A 1 487 ? 130.066 180.933 170.399 1.00 147.78 ? 492 HIS M CG    1 
ATOM   3783 N ND1   . HIS A 1 487 ? 129.090 181.443 169.572 1.00 147.78 ? 492 HIS M ND1   1 
ATOM   3784 C CD2   . HIS A 1 487 ? 129.423 180.436 171.480 1.00 147.78 ? 492 HIS M CD2   1 
ATOM   3785 C CE1   . HIS A 1 487 ? 127.907 181.260 170.128 1.00 147.78 ? 492 HIS M CE1   1 
ATOM   3786 N NE2   . HIS A 1 487 ? 128.081 180.652 171.287 1.00 147.78 ? 492 HIS M NE2   1 
ATOM   3787 N N     . MET A 1 488 ? 131.136 179.342 167.483 1.00 150.06 ? 493 MET M N     1 
ATOM   3788 C CA    . MET A 1 488 ? 130.336 178.668 166.469 1.00 150.06 ? 493 MET M CA    1 
ATOM   3789 C C     . MET A 1 488 ? 130.864 177.273 166.176 1.00 150.06 ? 493 MET M C     1 
ATOM   3790 O O     . MET A 1 488 ? 130.083 176.375 165.848 1.00 150.06 ? 493 MET M O     1 
ATOM   3791 C CB    . MET A 1 488 ? 130.298 179.503 165.189 1.00 150.06 ? 493 MET M CB    1 
ATOM   3792 C CG    . MET A 1 488 ? 129.554 178.851 164.032 1.00 150.06 ? 493 MET M CG    1 
ATOM   3793 S SD    . MET A 1 488 ? 129.340 179.958 162.625 1.00 150.06 ? 493 MET M SD    1 
ATOM   3794 C CE    . MET A 1 488 ? 131.033 180.430 162.300 1.00 150.06 ? 493 MET M CE    1 
ATOM   3795 N N     . PHE A 1 489 ? 132.177 177.064 166.288 1.00 152.26 ? 494 PHE M N     1 
ATOM   3796 C CA    . PHE A 1 489 ? 132.708 175.714 166.130 1.00 152.26 ? 494 PHE M CA    1 
ATOM   3797 C C     . PHE A 1 489 ? 132.135 174.781 167.182 1.00 152.26 ? 494 PHE M C     1 
ATOM   3798 O O     . PHE A 1 489 ? 131.694 173.667 166.873 1.00 152.26 ? 494 PHE M O     1 
ATOM   3799 C CB    . PHE A 1 489 ? 134.227 175.701 166.229 1.00 152.26 ? 494 PHE M CB    1 
ATOM   3800 C CG    . PHE A 1 489 ? 134.782 174.342 166.543 1.00 152.26 ? 494 PHE M CG    1 
ATOM   3801 C CD1   . PHE A 1 489 ? 134.856 173.370 165.561 1.00 152.26 ? 494 PHE M CD1   1 
ATOM   3802 C CD2   . PHE A 1 489 ? 135.203 174.026 167.822 1.00 152.26 ? 494 PHE M CD2   1 
ATOM   3803 C CE1   . PHE A 1 489 ? 135.356 172.114 165.845 1.00 152.26 ? 494 PHE M CE1   1 
ATOM   3804 C CE2   . PHE A 1 489 ? 135.704 172.773 168.112 1.00 152.26 ? 494 PHE M CE2   1 
ATOM   3805 C CZ    . PHE A 1 489 ? 135.781 171.816 167.121 1.00 152.26 ? 494 PHE M CZ    1 
ATOM   3806 N N     . VAL A 1 490 ? 132.170 175.208 168.444 1.00 155.52 ? 495 VAL M N     1 
ATOM   3807 C CA    . VAL A 1 490 ? 131.647 174.354 169.504 1.00 155.52 ? 495 VAL M CA    1 
ATOM   3808 C C     . VAL A 1 490 ? 130.143 174.173 169.343 1.00 155.52 ? 495 VAL M C     1 
ATOM   3809 O O     . VAL A 1 490 ? 129.599 173.105 169.640 1.00 155.52 ? 495 VAL M O     1 
ATOM   3810 C CB    . VAL A 1 490 ? 132.014 174.915 170.888 1.00 155.52 ? 495 VAL M CB    1 
ATOM   3811 C CG1   . VAL A 1 490 ? 131.550 173.967 171.980 1.00 155.52 ? 495 VAL M CG1   1 
ATOM   3812 C CG2   . VAL A 1 490 ? 133.509 175.133 170.978 1.00 155.52 ? 495 VAL M CG2   1 
ATOM   3813 N N     . LEU A 1 491 ? 129.452 175.199 168.839 1.00 157.32 ? 496 LEU M N     1 
ATOM   3814 C CA    . LEU A 1 491 ? 128.017 175.071 168.584 1.00 157.32 ? 496 LEU M CA    1 
ATOM   3815 C C     . LEU A 1 491 ? 127.726 174.047 167.493 1.00 157.32 ? 496 LEU M C     1 
ATOM   3816 O O     . LEU A 1 491 ? 126.765 173.275 167.597 1.00 157.32 ? 496 LEU M O     1 
ATOM   3817 C CB    . LEU A 1 491 ? 127.420 176.431 168.225 1.00 157.32 ? 496 LEU M CB    1 
ATOM   3818 C CG    . LEU A 1 491 ? 126.841 177.245 169.386 1.00 157.32 ? 496 LEU M CG    1 
ATOM   3819 C CD1   . LEU A 1 491 ? 125.597 176.561 169.908 1.00 157.32 ? 496 LEU M CD1   1 
ATOM   3820 C CD2   . LEU A 1 491 ? 127.842 177.415 170.511 1.00 157.32 ? 496 LEU M CD2   1 
ATOM   3821 N N     . GLU A 1 492 ? 128.539 174.024 166.439 1.00 162.46 ? 497 GLU M N     1 
ATOM   3822 C CA    . GLU A 1 492 ? 128.339 173.036 165.387 1.00 162.46 ? 497 GLU M CA    1 
ATOM   3823 C C     . GLU A 1 492 ? 128.681 171.638 165.882 1.00 162.46 ? 497 GLU M C     1 
ATOM   3824 O O     . GLU A 1 492 ? 128.021 170.662 165.511 1.00 162.46 ? 497 GLU M O     1 
ATOM   3825 C CB    . GLU A 1 492 ? 129.174 173.398 164.164 1.00 162.46 ? 497 GLU M CB    1 
ATOM   3826 C CG    . GLU A 1 492 ? 128.768 172.670 162.906 1.00 162.46 ? 497 GLU M CG    1 
ATOM   3827 C CD    . GLU A 1 492 ? 128.892 173.550 161.682 1.00 162.46 ? 497 GLU M CD    1 
ATOM   3828 O OE1   . GLU A 1 492 ? 129.792 173.299 160.853 1.00 162.46 ? 497 GLU M OE1   1 
ATOM   3829 O OE2   . GLU A 1 492 ? 128.094 174.502 161.555 1.00 162.46 ? 497 GLU M OE2   1 
ATOM   3830 N N     . GLN A 1 493 ? 129.705 171.523 166.729 1.00 162.29 ? 498 GLN M N     1 
ATOM   3831 C CA    . GLN A 1 493 ? 129.976 170.239 167.362 1.00 162.29 ? 498 GLN M CA    1 
ATOM   3832 C C     . GLN A 1 493 ? 128.814 169.806 168.243 1.00 162.29 ? 498 GLN M C     1 
ATOM   3833 O O     . GLN A 1 493 ? 128.525 168.611 168.346 1.00 162.29 ? 498 GLN M O     1 
ATOM   3834 C CB    . GLN A 1 493 ? 131.271 170.307 168.173 1.00 162.29 ? 498 GLN M CB    1 
ATOM   3835 C CG    . GLN A 1 493 ? 132.535 170.297 167.325 1.00 162.29 ? 498 GLN M CG    1 
ATOM   3836 C CD    . GLN A 1 493 ? 132.586 169.119 166.374 1.00 162.29 ? 498 GLN M CD    1 
ATOM   3837 O OE1   . GLN A 1 493 ? 132.941 168.010 166.766 1.00 162.29 ? 498 GLN M OE1   1 
ATOM   3838 N NE2   . GLN A 1 493 ? 132.221 169.352 165.117 1.00 162.29 ? 498 GLN M NE2   1 
ATOM   3839 N N     . GLU A 1 494 ? 128.130 170.762 168.873 1.00 165.30 ? 499 GLU M N     1 
ATOM   3840 C CA    . GLU A 1 494 ? 126.938 170.442 169.653 1.00 165.30 ? 499 GLU M CA    1 
ATOM   3841 C C     . GLU A 1 494 ? 125.814 169.930 168.756 1.00 165.30 ? 499 GLU M C     1 
ATOM   3842 O O     . GLU A 1 494 ? 125.160 168.928 169.069 1.00 165.30 ? 499 GLU M O     1 
ATOM   3843 C CB    . GLU A 1 494 ? 126.482 171.667 170.453 1.00 165.30 ? 499 GLU M CB    1 
ATOM   3844 C CG    . GLU A 1 494 ? 127.206 171.844 171.784 1.00 165.30 ? 499 GLU M CG    1 
ATOM   3845 C CD    . GLU A 1 494 ? 127.339 173.294 172.227 1.00 165.30 ? 499 GLU M CD    1 
ATOM   3846 O OE1   . GLU A 1 494 ? 127.808 174.127 171.433 1.00 165.30 ? 499 GLU M OE1   1 
ATOM   3847 O OE2   . GLU A 1 494 ? 126.980 173.599 173.383 1.00 165.30 ? 499 GLU M OE2   1 
ATOM   3848 N N     . GLU A 1 495 ? 125.570 170.618 167.640 1.00 170.72 ? 500 GLU M N     1 
ATOM   3849 C CA    . GLU A 1 495 ? 124.581 170.139 166.678 1.00 170.72 ? 500 GLU M CA    1 
ATOM   3850 C C     . GLU A 1 495 ? 124.905 168.722 166.217 1.00 170.72 ? 500 GLU M C     1 
ATOM   3851 O O     . GLU A 1 495 ? 124.015 167.867 166.125 1.00 170.72 ? 500 GLU M O     1 
ATOM   3852 C CB    . GLU A 1 495 ? 124.510 171.090 165.482 1.00 170.72 ? 500 GLU M CB    1 
ATOM   3853 C CG    . GLU A 1 495 ? 123.263 170.943 164.619 1.00 170.72 ? 500 GLU M CG    1 
ATOM   3854 C CD    . GLU A 1 495 ? 123.406 169.883 163.541 1.00 170.72 ? 500 GLU M CD    1 
ATOM   3855 O OE1   . GLU A 1 495 ? 124.520 169.348 163.367 1.00 170.72 ? 500 GLU M OE1   1 
ATOM   3856 O OE2   . GLU A 1 495 ? 122.399 169.588 162.862 1.00 170.72 ? 500 GLU M OE2   1 
ATOM   3857 N N     . TYR A 1 496 ? 126.180 168.452 165.938 1.00 172.12 ? 501 TYR M N     1 
ATOM   3858 C CA    . TYR A 1 496 ? 126.576 167.140 165.438 1.00 172.12 ? 501 TYR M CA    1 
ATOM   3859 C C     . TYR A 1 496 ? 126.439 166.064 166.508 1.00 172.12 ? 501 TYR M C     1 
ATOM   3860 O O     . TYR A 1 496 ? 125.966 164.958 166.222 1.00 172.12 ? 501 TYR M O     1 
ATOM   3861 C CB    . TYR A 1 496 ? 128.005 167.201 164.906 1.00 172.12 ? 501 TYR M CB    1 
ATOM   3862 C CG    . TYR A 1 496 ? 128.089 167.738 163.496 1.00 172.12 ? 501 TYR M CG    1 
ATOM   3863 C CD1   . TYR A 1 496 ? 127.006 167.641 162.635 1.00 172.12 ? 501 TYR M CD1   1 
ATOM   3864 C CD2   . TYR A 1 496 ? 129.245 168.344 163.026 1.00 172.12 ? 501 TYR M CD2   1 
ATOM   3865 C CE1   . TYR A 1 496 ? 127.071 168.128 161.349 1.00 172.12 ? 501 TYR M CE1   1 
ATOM   3866 C CE2   . TYR A 1 496 ? 129.318 168.833 161.738 1.00 172.12 ? 501 TYR M CE2   1 
ATOM   3867 C CZ    . TYR A 1 496 ? 128.227 168.723 160.904 1.00 172.12 ? 501 TYR M CZ    1 
ATOM   3868 O OH    . TYR A 1 496 ? 128.289 169.209 159.618 1.00 172.12 ? 501 TYR M OH    1 
ATOM   3869 N N     . LYS A 1 497 ? 126.851 166.358 167.743 1.00 170.26 ? 502 LYS M N     1 
ATOM   3870 C CA    . LYS A 1 497 ? 126.720 165.374 168.809 1.00 170.26 ? 502 LYS M CA    1 
ATOM   3871 C C     . LYS A 1 497 ? 125.267 165.144 169.192 1.00 170.26 ? 502 LYS M C     1 
ATOM   3872 O O     . LYS A 1 497 ? 124.944 164.084 169.739 1.00 170.26 ? 502 LYS M O     1 
ATOM   3873 C CB    . LYS A 1 497 ? 127.522 165.800 170.036 1.00 170.26 ? 502 LYS M CB    1 
ATOM   3874 C CG    . LYS A 1 497 ? 126.942 166.991 170.770 1.00 170.26 ? 502 LYS M CG    1 
ATOM   3875 C CD    . LYS A 1 497 ? 127.647 167.211 172.087 1.00 170.26 ? 502 LYS M CD    1 
ATOM   3876 C CE    . LYS A 1 497 ? 127.157 168.471 172.763 1.00 170.26 ? 502 LYS M CE    1 
ATOM   3877 N NZ    . LYS A 1 497 ? 125.681 168.509 172.862 1.00 170.26 ? 502 LYS M NZ    1 
ATOM   3878 N N     . LYS A 1 498 ? 124.389 166.114 168.924 1.00 173.83 ? 503 LYS M N     1 
ATOM   3879 C CA    . LYS A 1 498 ? 122.955 165.870 169.050 1.00 173.83 ? 503 LYS M CA    1 
ATOM   3880 C C     . LYS A 1 498 ? 122.472 164.943 167.944 1.00 173.83 ? 503 LYS M C     1 
ATOM   3881 O O     . LYS A 1 498 ? 121.803 163.937 168.208 1.00 173.83 ? 503 LYS M O     1 
ATOM   3882 C CB    . LYS A 1 498 ? 122.199 167.202 169.023 1.00 173.83 ? 503 LYS M CB    1 
ATOM   3883 C CG    . LYS A 1 498 ? 120.671 167.119 169.005 1.00 173.83 ? 503 LYS M CG    1 
ATOM   3884 C CD    . LYS A 1 498 ? 120.096 166.925 167.606 1.00 173.83 ? 503 LYS M CD    1 
ATOM   3885 C CE    . LYS A 1 498 ? 120.344 168.135 166.725 1.00 173.83 ? 503 LYS M CE    1 
ATOM   3886 N NZ    . LYS A 1 498 ? 119.721 167.973 165.377 1.00 173.83 ? 503 LYS M NZ    1 
ATOM   3887 N N     . GLU A 1 499 ? 122.798 165.271 166.695 1.00 178.47 ? 504 GLU M N     1 
ATOM   3888 C CA    . GLU A 1 499 ? 122.331 164.498 165.555 1.00 178.47 ? 504 GLU M CA    1 
ATOM   3889 C C     . GLU A 1 499 ? 122.985 163.124 165.477 1.00 178.47 ? 504 GLU M C     1 
ATOM   3890 O O     . GLU A 1 499 ? 122.551 162.284 164.680 1.00 178.47 ? 504 GLU M O     1 
ATOM   3891 C CB    . GLU A 1 499 ? 122.567 165.304 164.266 1.00 178.47 ? 504 GLU M CB    1 
ATOM   3892 C CG    . GLU A 1 499 ? 122.255 164.616 162.929 1.00 178.47 ? 504 GLU M CG    1 
ATOM   3893 C CD    . GLU A 1 499 ? 120.822 164.124 162.791 1.00 178.47 ? 504 GLU M CD    1 
ATOM   3894 O OE1   . GLU A 1 499 ? 120.487 163.561 161.728 1.00 178.47 ? 504 GLU M OE1   1 
ATOM   3895 O OE2   . GLU A 1 499 ? 120.024 164.299 163.730 1.00 178.47 ? 504 GLU M OE2   1 
ATOM   3896 N N     . GLY A 1 500 ? 123.978 162.853 166.319 1.00 177.11 ? 505 GLY M N     1 
ATOM   3897 C CA    . GLY A 1 500 ? 124.636 161.566 166.268 1.00 177.11 ? 505 GLY M CA    1 
ATOM   3898 C C     . GLY A 1 500 ? 125.491 161.367 165.042 1.00 177.11 ? 505 GLY M C     1 
ATOM   3899 O O     . GLY A 1 500 ? 125.817 160.227 164.704 1.00 177.11 ? 505 GLY M O     1 
ATOM   3900 N N     . ILE A 1 501 ? 125.863 162.448 164.366 1.00 177.59 ? 506 ILE M N     1 
ATOM   3901 C CA    . ILE A 1 501 ? 126.666 162.391 163.147 1.00 177.59 ? 506 ILE M CA    1 
ATOM   3902 C C     . ILE A 1 501 ? 127.871 163.303 163.378 1.00 177.59 ? 506 ILE M C     1 
ATOM   3903 O O     . ILE A 1 501 ? 127.771 164.531 163.433 1.00 177.59 ? 506 ILE M O     1 
ATOM   3904 C CB    . ILE A 1 501 ? 125.852 162.758 161.897 1.00 177.59 ? 506 ILE M CB    1 
ATOM   3905 C CG1   . ILE A 1 501 ? 126.554 162.294 160.626 1.00 177.59 ? 506 ILE M CG1   1 
ATOM   3906 C CG2   . ILE A 1 501 ? 125.476 164.239 161.822 1.00 177.59 ? 506 ILE M CG2   1 
ATOM   3907 C CD1   . ILE A 1 501 ? 125.598 161.974 159.512 1.00 177.59 ? 506 ILE M CD1   1 
ATOM   3908 N N     . GLU A 1 502 ? 129.036 162.698 163.594 1.00 175.76 ? 507 GLU M N     1 
ATOM   3909 C CA    . GLU A 1 502 ? 130.213 163.422 164.068 1.00 175.76 ? 507 GLU M CA    1 
ATOM   3910 C C     . GLU A 1 502 ? 131.382 163.218 163.110 1.00 175.76 ? 507 GLU M C     1 
ATOM   3911 O O     . GLU A 1 502 ? 131.931 162.115 163.014 1.00 175.76 ? 507 GLU M O     1 
ATOM   3912 C CB    . GLU A 1 502 ? 130.575 162.983 165.487 1.00 175.76 ? 507 GLU M CB    1 
ATOM   3913 C CG    . GLU A 1 502 ? 129.535 163.371 166.533 1.00 175.76 ? 507 GLU M CG    1 
ATOM   3914 C CD    . GLU A 1 502 ? 128.345 162.431 166.561 1.00 175.76 ? 507 GLU M CD    1 
ATOM   3915 O OE1   . GLU A 1 502 ? 127.392 162.698 167.320 1.00 175.76 ? 507 GLU M OE1   1 
ATOM   3916 O OE2   . GLU A 1 502 ? 128.365 161.421 165.826 1.00 175.76 ? 507 GLU M OE2   1 
ATOM   3917 N N     . TRP A 1 503 ? 131.773 164.291 162.426 1.00 173.62 ? 508 TRP M N     1 
ATOM   3918 C CA    . TRP A 1 503 ? 132.847 164.261 161.445 1.00 173.62 ? 508 TRP M CA    1 
ATOM   3919 C C     . TRP A 1 503 ? 133.552 165.612 161.453 1.00 173.62 ? 508 TRP M C     1 
ATOM   3920 O O     . TRP A 1 503 ? 133.098 166.567 162.089 1.00 173.62 ? 508 TRP M O     1 
ATOM   3921 C CB    . TRP A 1 503 ? 132.311 163.934 160.045 1.00 173.62 ? 508 TRP M CB    1 
ATOM   3922 C CG    . TRP A 1 503 ? 132.276 162.471 159.708 1.00 173.62 ? 508 TRP M CG    1 
ATOM   3923 C CD1   . TRP A 1 503 ? 133.220 161.773 159.013 1.00 173.62 ? 508 TRP M CD1   1 
ATOM   3924 C CD2   . TRP A 1 503 ? 131.245 161.528 160.037 1.00 173.62 ? 508 TRP M CD2   1 
ATOM   3925 N NE1   . TRP A 1 503 ? 132.847 160.458 158.893 1.00 173.62 ? 508 TRP M NE1   1 
ATOM   3926 C CE2   . TRP A 1 503 ? 131.639 160.280 159.514 1.00 173.62 ? 508 TRP M CE2   1 
ATOM   3927 C CE3   . TRP A 1 503 ? 130.030 161.615 160.720 1.00 173.62 ? 508 TRP M CE3   1 
ATOM   3928 C CZ2   . TRP A 1 503 ? 130.863 159.132 159.657 1.00 173.62 ? 508 TRP M CZ2   1 
ATOM   3929 C CZ3   . TRP A 1 503 ? 129.270 160.470 160.869 1.00 173.62 ? 508 TRP M CZ3   1 
ATOM   3930 C CH2   . TRP A 1 503 ? 129.684 159.249 160.334 1.00 173.62 ? 508 TRP M CH2   1 
ATOM   3931 N N     . THR A 1 504 ? 134.680 165.679 160.739 1.00 168.51 ? 509 THR M N     1 
ATOM   3932 C CA    . THR A 1 504 ? 135.422 166.926 160.511 1.00 168.51 ? 509 THR M CA    1 
ATOM   3933 C C     . THR A 1 504 ? 135.806 167.597 161.831 1.00 168.51 ? 509 THR M C     1 
ATOM   3934 O O     . THR A 1 504 ? 135.354 168.695 162.160 1.00 168.51 ? 509 THR M O     1 
ATOM   3935 C CB    . THR A 1 504 ? 134.628 167.886 159.618 1.00 168.51 ? 509 THR M CB    1 
ATOM   3936 O OG1   . THR A 1 504 ? 133.539 168.450 160.362 1.00 168.51 ? 509 THR M OG1   1 
ATOM   3937 C CG2   . THR A 1 504 ? 134.088 167.154 158.394 1.00 168.51 ? 509 THR M CG2   1 
ATOM   3938 N N     . PHE A 1 505 ? 136.660 166.911 162.587 1.00 165.52 ? 510 PHE M N     1 
ATOM   3939 C CA    . PHE A 1 505 ? 136.995 167.302 163.951 1.00 165.52 ? 510 PHE M CA    1 
ATOM   3940 C C     . PHE A 1 505 ? 138.052 168.411 164.031 1.00 165.52 ? 510 PHE M C     1 
ATOM   3941 O O     . PHE A 1 505 ? 138.674 168.573 165.087 1.00 165.52 ? 510 PHE M O     1 
ATOM   3942 C CB    . PHE A 1 505 ? 137.466 166.079 164.742 1.00 165.52 ? 510 PHE M CB    1 
ATOM   3943 C CG    . PHE A 1 505 ? 136.400 165.041 164.944 1.00 165.52 ? 510 PHE M CG    1 
ATOM   3944 C CD1   . PHE A 1 505 ? 135.318 165.293 165.773 1.00 165.52 ? 510 PHE M CD1   1 
ATOM   3945 C CD2   . PHE A 1 505 ? 136.479 163.813 164.310 1.00 165.52 ? 510 PHE M CD2   1 
ATOM   3946 C CE1   . PHE A 1 505 ? 134.335 164.341 165.962 1.00 165.52 ? 510 PHE M CE1   1 
ATOM   3947 C CE2   . PHE A 1 505 ? 135.501 162.858 164.497 1.00 165.52 ? 510 PHE M CE2   1 
ATOM   3948 C CZ    . PHE A 1 505 ? 134.428 163.124 165.322 1.00 165.52 ? 510 PHE M CZ    1 
ATOM   3949 N N     . ILE A 1 506 ? 138.274 169.170 162.962 1.00 156.64 ? 511 ILE M N     1 
ATOM   3950 C CA    . ILE A 1 506 ? 139.180 170.313 163.019 1.00 156.64 ? 511 ILE M CA    1 
ATOM   3951 C C     . ILE A 1 506 ? 138.419 171.535 163.517 1.00 156.64 ? 511 ILE M C     1 
ATOM   3952 O O     . ILE A 1 506 ? 137.256 171.750 163.157 1.00 156.64 ? 511 ILE M O     1 
ATOM   3953 C CB    . ILE A 1 506 ? 139.826 170.567 161.647 1.00 156.64 ? 511 ILE M CB    1 
ATOM   3954 C CG1   . ILE A 1 506 ? 140.874 171.675 161.749 1.00 156.64 ? 511 ILE M CG1   1 
ATOM   3955 C CG2   . ILE A 1 506 ? 138.774 170.884 160.594 1.00 156.64 ? 511 ILE M CG2   1 
ATOM   3956 C CD1   . ILE A 1 506 ? 142.037 171.329 162.633 1.00 156.64 ? 511 ILE M CD1   1 
ATOM   3957 N N     . ASP A 1 507 ? 139.064 172.326 164.368 1.00 148.77 ? 512 ASP M N     1 
ATOM   3958 C CA    . ASP A 1 507 ? 138.442 173.539 164.874 1.00 148.77 ? 512 ASP M CA    1 
ATOM   3959 C C     . ASP A 1 507 ? 138.519 174.652 163.830 1.00 148.77 ? 512 ASP M C     1 
ATOM   3960 O O     . ASP A 1 507 ? 139.252 174.572 162.843 1.00 148.77 ? 512 ASP M O     1 
ATOM   3961 C CB    . ASP A 1 507 ? 139.103 173.970 166.188 1.00 148.77 ? 512 ASP M CB    1 
ATOM   3962 C CG    . ASP A 1 507 ? 138.339 175.068 166.909 1.00 148.77 ? 512 ASP M CG    1 
ATOM   3963 O OD1   . ASP A 1 507 ? 137.484 175.728 166.283 1.00 148.77 ? 512 ASP M OD1   1 
ATOM   3964 O OD2   . ASP A 1 507 ? 138.592 175.270 168.114 1.00 148.77 ? 512 ASP M OD2   1 
ATOM   3965 N N     . PHE A 1 508 ? 137.730 175.697 164.060 1.00 146.41 ? 513 PHE M N     1 
ATOM   3966 C CA    . PHE A 1 508 ? 137.606 176.812 163.136 1.00 146.41 ? 513 PHE M CA    1 
ATOM   3967 C C     . PHE A 1 508 ? 138.298 178.072 163.630 1.00 146.41 ? 513 PHE M C     1 
ATOM   3968 O O     . PHE A 1 508 ? 138.078 179.144 163.063 1.00 146.41 ? 513 PHE M O     1 
ATOM   3969 C CB    . PHE A 1 508 ? 136.129 177.108 162.877 1.00 146.41 ? 513 PHE M CB    1 
ATOM   3970 C CG    . PHE A 1 508 ? 135.364 175.941 162.327 1.00 146.41 ? 513 PHE M CG    1 
ATOM   3971 C CD1   . PHE A 1 508 ? 135.883 175.180 161.297 1.00 146.41 ? 513 PHE M CD1   1 
ATOM   3972 C CD2   . PHE A 1 508 ? 134.131 175.597 162.851 1.00 146.41 ? 513 PHE M CD2   1 
ATOM   3973 C CE1   . PHE A 1 508 ? 135.180 174.107 160.793 1.00 146.41 ? 513 PHE M CE1   1 
ATOM   3974 C CE2   . PHE A 1 508 ? 133.428 174.528 162.357 1.00 146.41 ? 513 PHE M CE2   1 
ATOM   3975 C CZ    . PHE A 1 508 ? 133.951 173.780 161.326 1.00 146.41 ? 513 PHE M CZ    1 
ATOM   3976 N N     . GLY A 1 509 ? 139.130 177.976 164.662 1.00 136.55 ? 514 GLY M N     1 
ATOM   3977 C CA    . GLY A 1 509 ? 139.746 179.162 165.226 1.00 136.55 ? 514 GLY M CA    1 
ATOM   3978 C C     . GLY A 1 509 ? 141.181 179.394 164.800 1.00 136.55 ? 514 GLY M C     1 
ATOM   3979 O O     . GLY A 1 509 ? 141.599 180.536 164.584 1.00 136.55 ? 514 GLY M O     1 
ATOM   3980 N N     . MET A 1 510 ? 141.949 178.310 164.683 1.00 132.79 ? 515 MET M N     1 
ATOM   3981 C CA    . MET A 1 510 ? 143.376 178.441 164.419 1.00 132.79 ? 515 MET M CA    1 
ATOM   3982 C C     . MET A 1 510 ? 143.645 179.114 163.081 1.00 132.79 ? 515 MET M C     1 
ATOM   3983 O O     . MET A 1 510 ? 144.633 179.850 162.938 1.00 132.79 ? 515 MET M O     1 
ATOM   3984 C CB    . MET A 1 510 ? 144.035 177.066 164.465 1.00 132.79 ? 515 MET M CB    1 
ATOM   3985 C CG    . MET A 1 510 ? 144.193 176.526 165.868 1.00 132.79 ? 515 MET M CG    1 
ATOM   3986 S SD    . MET A 1 510 ? 142.631 175.943 166.539 1.00 132.79 ? 515 MET M SD    1 
ATOM   3987 C CE    . MET A 1 510 ? 142.494 174.381 165.687 1.00 132.79 ? 515 MET M CE    1 
ATOM   3988 N N     . ASP A 1 511 ? 142.781 178.872 162.093 1.00 133.55 ? 516 ASP M N     1 
ATOM   3989 C CA    . ASP A 1 511 ? 142.950 179.487 160.783 1.00 133.55 ? 516 ASP M CA    1 
ATOM   3990 C C     . ASP A 1 511 ? 142.977 181.002 160.878 1.00 133.55 ? 516 ASP M C     1 
ATOM   3991 O O     . ASP A 1 511 ? 143.532 181.672 160.001 1.00 133.55 ? 516 ASP M O     1 
ATOM   3992 C CB    . ASP A 1 511 ? 141.831 179.028 159.856 1.00 133.55 ? 516 ASP M CB    1 
ATOM   3993 C CG    . ASP A 1 511 ? 140.515 178.910 160.576 1.00 133.55 ? 516 ASP M CG    1 
ATOM   3994 O OD1   . ASP A 1 511 ? 140.512 179.131 161.804 1.00 133.55 ? 516 ASP M OD1   1 
ATOM   3995 O OD2   . ASP A 1 511 ? 139.493 178.596 159.928 1.00 133.55 ? 516 ASP M OD2   1 
ATOM   3996 N N     . LEU A 1 512 ? 142.389 181.558 161.932 1.00 126.76 ? 517 LEU M N     1 
ATOM   3997 C CA    . LEU A 1 512 ? 142.491 182.984 162.199 1.00 126.76 ? 517 LEU M CA    1 
ATOM   3998 C C     . LEU A 1 512 ? 143.566 183.318 163.220 1.00 126.76 ? 517 LEU M C     1 
ATOM   3999 O O     . LEU A 1 512 ? 144.187 184.380 163.120 1.00 126.76 ? 517 LEU M O     1 
ATOM   4000 C CB    . LEU A 1 512 ? 141.146 183.526 162.682 1.00 126.76 ? 517 LEU M CB    1 
ATOM   4001 C CG    . LEU A 1 512 ? 141.011 185.027 162.495 1.00 126.76 ? 517 LEU M CG    1 
ATOM   4002 C CD1   . LEU A 1 512 ? 141.348 185.383 161.062 1.00 126.76 ? 517 LEU M CD1   1 
ATOM   4003 C CD2   . LEU A 1 512 ? 139.611 185.458 162.842 1.00 126.76 ? 517 LEU M CD2   1 
ATOM   4004 N N     . GLN A 1 513 ? 143.799 182.434 164.194 1.00 122.08 ? 518 GLN M N     1 
ATOM   4005 C CA    . GLN A 1 513 ? 144.862 182.664 165.168 1.00 122.08 ? 518 GLN M CA    1 
ATOM   4006 C C     . GLN A 1 513 ? 146.210 182.853 164.491 1.00 122.08 ? 518 GLN M C     1 
ATOM   4007 O O     . GLN A 1 513 ? 147.064 183.595 164.994 1.00 122.08 ? 518 GLN M O     1 
ATOM   4008 C CB    . GLN A 1 513 ? 144.945 181.497 166.145 1.00 122.08 ? 518 GLN M CB    1 
ATOM   4009 C CG    . GLN A 1 513 ? 146.118 181.586 167.094 1.00 122.08 ? 518 GLN M CG    1 
ATOM   4010 C CD    . GLN A 1 513 ? 146.451 180.258 167.717 1.00 122.08 ? 518 GLN M CD    1 
ATOM   4011 O OE1   . GLN A 1 513 ? 145.925 179.223 167.313 1.00 122.08 ? 518 GLN M OE1   1 
ATOM   4012 N NE2   . GLN A 1 513 ? 147.326 180.274 168.714 1.00 122.08 ? 518 GLN M NE2   1 
ATOM   4013 N N     . ALA A 1 514 ? 146.422 182.180 163.361 1.00 117.16 ? 519 ALA M N     1 
ATOM   4014 C CA    . ALA A 1 514 ? 147.675 182.345 162.634 1.00 117.16 ? 519 ALA M CA    1 
ATOM   4015 C C     . ALA A 1 514 ? 147.950 183.807 162.307 1.00 117.16 ? 519 ALA M C     1 
ATOM   4016 O O     . ALA A 1 514 ? 149.112 184.215 162.231 1.00 117.16 ? 519 ALA M O     1 
ATOM   4017 C CB    . ALA A 1 514 ? 147.658 181.506 161.357 1.00 117.16 ? 519 ALA M CB    1 
ATOM   4018 N N     . CYS A 1 515 ? 146.904 184.613 162.117 1.00 114.52 ? 520 CYS M N     1 
ATOM   4019 C CA    . CYS A 1 515 ? 147.115 186.043 161.921 1.00 114.52 ? 520 CYS M CA    1 
ATOM   4020 C C     . CYS A 1 515 ? 147.348 186.774 163.234 1.00 114.52 ? 520 CYS M C     1 
ATOM   4021 O O     . CYS A 1 515 ? 148.045 187.791 163.251 1.00 114.52 ? 520 CYS M O     1 
ATOM   4022 C CB    . CYS A 1 515 ? 145.931 186.673 161.194 1.00 114.52 ? 520 CYS M CB    1 
ATOM   4023 S SG    . CYS A 1 515 ? 146.079 188.460 161.014 1.00 114.52 ? 520 CYS M SG    1 
ATOM   4024 N N     . ILE A 1 516 ? 146.775 186.287 164.335 1.00 112.17 ? 521 ILE M N     1 
ATOM   4025 C CA    . ILE A 1 516 ? 147.032 186.914 165.627 1.00 112.17 ? 521 ILE M CA    1 
ATOM   4026 C C     . ILE A 1 516 ? 148.498 186.770 165.999 1.00 112.17 ? 521 ILE M C     1 
ATOM   4027 O O     . ILE A 1 516 ? 149.129 187.721 166.477 1.00 112.17 ? 521 ILE M O     1 
ATOM   4028 C CB    . ILE A 1 516 ? 146.117 186.318 166.710 1.00 112.17 ? 521 ILE M CB    1 
ATOM   4029 C CG1   . ILE A 1 516 ? 144.664 186.704 166.450 1.00 112.17 ? 521 ILE M CG1   1 
ATOM   4030 C CG2   . ILE A 1 516 ? 146.540 186.798 168.072 1.00 112.17 ? 521 ILE M CG2   1 
ATOM   4031 C CD1   . ILE A 1 516 ? 143.708 186.221 167.512 1.00 112.17 ? 521 ILE M CD1   1 
ATOM   4032 N N     . ASP A 1 517 ? 149.074 185.590 165.754 1.00 108.31 ? 522 ASP M N     1 
ATOM   4033 C CA    . ASP A 1 517 ? 150.468 185.332 166.099 1.00 108.31 ? 522 ASP M CA    1 
ATOM   4034 C C     . ASP A 1 517 ? 151.433 186.296 165.428 1.00 108.31 ? 522 ASP M C     1 
ATOM   4035 O O     . ASP A 1 517 ? 152.618 186.296 165.771 1.00 108.31 ? 522 ASP M O     1 
ATOM   4036 C CB    . ASP A 1 517 ? 150.854 183.905 165.719 1.00 108.31 ? 522 ASP M CB    1 
ATOM   4037 C CG    . ASP A 1 517 ? 150.100 182.869 166.509 1.00 108.31 ? 522 ASP M CG    1 
ATOM   4038 O OD1   . ASP A 1 517 ? 149.358 182.084 165.888 1.00 108.31 ? 522 ASP M OD1   1 
ATOM   4039 O OD2   . ASP A 1 517 ? 150.245 182.834 167.747 1.00 108.31 ? 522 ASP M OD2   1 
ATOM   4040 N N     . LEU A 1 518 ? 150.966 187.099 164.481 1.00 101.57 ? 523 LEU M N     1 
ATOM   4041 C CA    . LEU A 1 518 ? 151.793 188.079 163.803 1.00 101.57 ? 523 LEU M CA    1 
ATOM   4042 C C     . LEU A 1 518 ? 151.717 189.448 164.454 1.00 101.57 ? 523 LEU M C     1 
ATOM   4043 O O     . LEU A 1 518 ? 152.331 190.394 163.961 1.00 101.57 ? 523 LEU M O     1 
ATOM   4044 C CB    . LEU A 1 518 ? 151.378 188.179 162.340 1.00 101.57 ? 523 LEU M CB    1 
ATOM   4045 C CG    . LEU A 1 518 ? 152.408 188.748 161.377 1.00 101.57 ? 523 LEU M CG    1 
ATOM   4046 C CD1   . LEU A 1 518 ? 153.629 187.860 161.337 1.00 101.57 ? 523 LEU M CD1   1 
ATOM   4047 C CD2   . LEU A 1 518 ? 151.784 188.887 160.013 1.00 101.57 ? 523 LEU M CD2   1 
ATOM   4048 N N     . ILE A 1 519 ? 150.982 189.581 165.549 1.00 100.15 ? 524 ILE M N     1 
ATOM   4049 C CA    . ILE A 1 519 ? 150.870 190.840 166.271 1.00 100.15 ? 524 ILE M CA    1 
ATOM   4050 C C     . ILE A 1 519 ? 151.366 190.704 167.703 1.00 100.15 ? 524 ILE M C     1 
ATOM   4051 O O     . ILE A 1 519 ? 152.222 191.469 168.151 1.00 100.15 ? 524 ILE M O     1 
ATOM   4052 C CB    . ILE A 1 519 ? 149.425 191.377 166.246 1.00 100.15 ? 524 ILE M CB    1 
ATOM   4053 C CG1   . ILE A 1 519 ? 148.872 191.375 164.825 1.00 100.15 ? 524 ILE M CG1   1 
ATOM   4054 C CG2   . ILE A 1 519 ? 149.382 192.787 166.807 1.00 100.15 ? 524 ILE M CG2   1 
ATOM   4055 C CD1   . ILE A 1 519 ? 149.345 192.524 163.997 1.00 100.15 ? 524 ILE M CD1   1 
ATOM   4056 N N     . GLU A 1 520 ? 150.851 189.721 168.432 1.00 102.39 ? 525 GLU M N     1 
ATOM   4057 C CA    . GLU A 1 520 ? 151.145 189.619 169.852 1.00 102.39 ? 525 GLU M CA    1 
ATOM   4058 C C     . GLU A 1 520 ? 152.387 188.798 170.153 1.00 102.39 ? 525 GLU M C     1 
ATOM   4059 O O     . GLU A 1 520 ? 153.111 189.118 171.101 1.00 102.39 ? 525 GLU M O     1 
ATOM   4060 C CB    . GLU A 1 520 ? 149.951 189.015 170.592 1.00 102.39 ? 525 GLU M CB    1 
ATOM   4061 C CG    . GLU A 1 520 ? 149.678 187.558 170.267 1.00 102.39 ? 525 GLU M CG    1 
ATOM   4062 C CD    . GLU A 1 520 ? 148.446 187.033 170.967 1.00 102.39 ? 525 GLU M CD    1 
ATOM   4063 O OE1   . GLU A 1 520 ? 147.787 187.818 171.676 1.00 102.39 ? 525 GLU M OE1   1 
ATOM   4064 O OE2   . GLU A 1 520 ? 148.131 185.838 170.807 1.00 102.39 ? 525 GLU M OE2   1 
ATOM   4065 N N     . LYS A 1 521 ? 152.656 187.754 169.377 1.00 96.93  ? 526 LYS M N     1 
ATOM   4066 C CA    . LYS A 1 521 ? 153.696 186.810 169.735 1.00 96.93  ? 526 LYS M CA    1 
ATOM   4067 C C     . LYS A 1 521 ? 155.068 187.472 169.702 1.00 96.93  ? 526 LYS M C     1 
ATOM   4068 O O     . LYS A 1 521 ? 155.270 188.470 169.010 1.00 96.93  ? 526 LYS M O     1 
ATOM   4069 C CB    . LYS A 1 521 ? 153.662 185.612 168.796 1.00 96.93  ? 526 LYS M CB    1 
ATOM   4070 C CG    . LYS A 1 521 ? 152.583 184.617 169.147 1.00 96.93  ? 526 LYS M CG    1 
ATOM   4071 C CD    . LYS A 1 521 ? 152.801 184.061 170.537 1.00 96.93  ? 526 LYS M CD    1 
ATOM   4072 C CE    . LYS A 1 521 ? 151.646 183.180 170.974 1.00 96.93  ? 526 LYS M CE    1 
ATOM   4073 N NZ    . LYS A 1 521 ? 150.416 183.974 171.215 1.00 96.93  ? 526 LYS M NZ    1 
ATOM   4074 N N     . PRO A 1 522 ? 156.022 186.946 170.470 1.00 89.66  ? 527 PRO M N     1 
ATOM   4075 C CA    . PRO A 1 522 ? 157.383 187.488 170.427 1.00 89.66  ? 527 PRO M CA    1 
ATOM   4076 C C     . PRO A 1 522 ? 157.950 187.415 169.020 1.00 89.66  ? 527 PRO M C     1 
ATOM   4077 O O     . PRO A 1 522 ? 157.715 186.454 168.287 1.00 89.66  ? 527 PRO M O     1 
ATOM   4078 C CB    . PRO A 1 522 ? 158.151 186.586 171.395 1.00 89.66  ? 527 PRO M CB    1 
ATOM   4079 C CG    . PRO A 1 522 ? 157.109 186.069 172.322 1.00 89.66  ? 527 PRO M CG    1 
ATOM   4080 C CD    . PRO A 1 522 ? 155.884 185.888 171.484 1.00 89.66  ? 527 PRO M CD    1 
ATOM   4081 N N     . MET A 1 523 ? 158.693 188.456 168.649 1.00 85.26  ? 528 MET M N     1 
ATOM   4082 C CA    . MET A 1 523 ? 159.149 188.721 167.287 1.00 85.26  ? 528 MET M CA    1 
ATOM   4083 C C     . MET A 1 523 ? 158.008 189.078 166.346 1.00 85.26  ? 528 MET M C     1 
ATOM   4084 O O     . MET A 1 523 ? 158.239 189.252 165.146 1.00 85.26  ? 528 MET M O     1 
ATOM   4085 C CB    . MET A 1 523 ? 159.959 187.551 166.723 1.00 85.26  ? 528 MET M CB    1 
ATOM   4086 C CG    . MET A 1 523 ? 161.350 187.462 167.300 1.00 85.26  ? 528 MET M CG    1 
ATOM   4087 S SD    . MET A 1 523 ? 162.427 188.734 166.634 1.00 85.26  ? 528 MET M SD    1 
ATOM   4088 C CE    . MET A 1 523 ? 162.464 189.932 167.924 1.00 85.26  ? 528 MET M CE    1 
ATOM   4089 N N     . GLY A 1 524 ? 156.785 189.204 166.856 1.00 87.60  ? 529 GLY M N     1 
ATOM   4090 C CA    . GLY A 1 524 ? 155.688 189.757 166.096 1.00 87.60  ? 529 GLY M CA    1 
ATOM   4091 C C     . GLY A 1 524 ? 155.810 191.263 165.993 1.00 87.60  ? 529 GLY M C     1 
ATOM   4092 O O     . GLY A 1 524 ? 156.765 191.875 166.468 1.00 87.60  ? 529 GLY M O     1 
ATOM   4093 N N     . ILE A 1 525 ? 154.810 191.870 165.358 1.00 87.98  ? 530 ILE M N     1 
ATOM   4094 C CA    . ILE A 1 525 ? 154.902 193.289 165.029 1.00 87.98  ? 530 ILE M CA    1 
ATOM   4095 C C     . ILE A 1 525 ? 154.964 194.135 166.290 1.00 87.98  ? 530 ILE M C     1 
ATOM   4096 O O     . ILE A 1 525 ? 155.762 195.074 166.386 1.00 87.98  ? 530 ILE M O     1 
ATOM   4097 C CB    . ILE A 1 525 ? 153.731 193.702 164.126 1.00 87.98  ? 530 ILE M CB    1 
ATOM   4098 C CG1   . ILE A 1 525 ? 153.825 192.966 162.795 1.00 87.98  ? 530 ILE M CG1   1 
ATOM   4099 C CG2   . ILE A 1 525 ? 153.741 195.196 163.900 1.00 87.98  ? 530 ILE M CG2   1 
ATOM   4100 C CD1   . ILE A 1 525 ? 152.796 193.393 161.798 1.00 87.98  ? 530 ILE M CD1   1 
ATOM   4101 N N     . MET A 1 526 ? 154.139 193.814 167.283 1.00 89.40  ? 531 MET M N     1 
ATOM   4102 C CA    . MET A 1 526 ? 154.137 194.607 168.505 1.00 89.40  ? 531 MET M CA    1 
ATOM   4103 C C     . MET A 1 526 ? 155.441 194.449 169.275 1.00 89.40  ? 531 MET M C     1 
ATOM   4104 O O     . MET A 1 526 ? 155.969 195.426 169.815 1.00 89.40  ? 531 MET M O     1 
ATOM   4105 C CB    . MET A 1 526 ? 152.945 194.223 169.375 1.00 89.40  ? 531 MET M CB    1 
ATOM   4106 C CG    . MET A 1 526 ? 151.624 194.750 168.853 1.00 89.40  ? 531 MET M CG    1 
ATOM   4107 S SD    . MET A 1 526 ? 151.742 196.482 168.365 1.00 89.40  ? 531 MET M SD    1 
ATOM   4108 C CE    . MET A 1 526 ? 150.018 196.928 168.215 1.00 89.40  ? 531 MET M CE    1 
ATOM   4109 N N     . SER A 1 527 ? 155.981 193.234 169.333 1.00 83.69  ? 532 SER M N     1 
ATOM   4110 C CA    . SER A 1 527 ? 157.238 193.041 170.045 1.00 83.69  ? 532 SER M CA    1 
ATOM   4111 C C     . SER A 1 527 ? 158.382 193.749 169.336 1.00 83.69  ? 532 SER M C     1 
ATOM   4112 O O     . SER A 1 527 ? 159.252 194.338 169.985 1.00 83.69  ? 532 SER M O     1 
ATOM   4113 C CB    . SER A 1 527 ? 157.536 191.556 170.194 1.00 83.69  ? 532 SER M CB    1 
ATOM   4114 O OG    . SER A 1 527 ? 157.734 190.968 168.932 1.00 83.69  ? 532 SER M OG    1 
ATOM   4115 N N     . ILE A 1 528 ? 158.394 193.711 168.006 1.00 82.07  ? 533 ILE M N     1 
ATOM   4116 C CA    . ILE A 1 528 ? 159.424 194.425 167.265 1.00 82.07  ? 533 ILE M CA    1 
ATOM   4117 C C     . ILE A 1 528 ? 159.291 195.921 167.486 1.00 82.07  ? 533 ILE M C     1 
ATOM   4118 O O     . ILE A 1 528 ? 160.288 196.637 167.601 1.00 82.07  ? 533 ILE M O     1 
ATOM   4119 C CB    . ILE A 1 528 ? 159.356 194.069 165.773 1.00 82.07  ? 533 ILE M CB    1 
ATOM   4120 C CG1   . ILE A 1 528 ? 159.722 192.608 165.564 1.00 82.07  ? 533 ILE M CG1   1 
ATOM   4121 C CG2   . ILE A 1 528 ? 160.282 194.951 164.985 1.00 82.07  ? 533 ILE M CG2   1 
ATOM   4122 C CD1   . ILE A 1 528 ? 159.760 192.214 164.131 1.00 82.07  ? 533 ILE M CD1   1 
ATOM   4123 N N     . LEU A 1 529 ? 158.061 196.416 167.570 1.00 82.63  ? 534 LEU M N     1 
ATOM   4124 C CA    . LEU A 1 529 ? 157.872 197.841 167.799 1.00 82.63  ? 534 LEU M CA    1 
ATOM   4125 C C     . LEU A 1 529 ? 158.358 198.246 169.181 1.00 82.63  ? 534 LEU M C     1 
ATOM   4126 O O     . LEU A 1 529 ? 159.007 199.286 169.337 1.00 82.63  ? 534 LEU M O     1 
ATOM   4127 C CB    . LEU A 1 529 ? 156.403 198.203 167.613 1.00 82.63  ? 534 LEU M CB    1 
ATOM   4128 C CG    . LEU A 1 529 ? 156.000 199.635 167.927 1.00 82.63  ? 534 LEU M CG    1 
ATOM   4129 C CD1   . LEU A 1 529 ? 156.791 200.621 167.104 1.00 82.63  ? 534 LEU M CD1   1 
ATOM   4130 C CD2   . LEU A 1 529 ? 154.536 199.784 167.660 1.00 82.63  ? 534 LEU M CD2   1 
ATOM   4131 N N     . GLU A 1 530 ? 158.051 197.439 170.197 1.00 83.12  ? 535 GLU M N     1 
ATOM   4132 C CA    . GLU A 1 530 ? 158.533 197.722 171.546 1.00 83.12  ? 535 GLU M CA    1 
ATOM   4133 C C     . GLU A 1 530 ? 160.055 197.715 171.593 1.00 83.12  ? 535 GLU M C     1 
ATOM   4134 O O     . GLU A 1 530 ? 160.684 198.642 172.124 1.00 83.12  ? 535 GLU M O     1 
ATOM   4135 C CB    . GLU A 1 530 ? 157.960 196.700 172.522 1.00 83.12  ? 535 GLU M CB    1 
ATOM   4136 C CG    . GLU A 1 530 ? 156.468 196.826 172.733 1.00 83.12  ? 535 GLU M CG    1 
ATOM   4137 C CD    . GLU A 1 530 ? 155.816 195.505 173.075 1.00 83.12  ? 535 GLU M CD    1 
ATOM   4138 O OE1   . GLU A 1 530 ? 156.494 194.462 172.983 1.00 83.12  ? 535 GLU M OE1   1 
ATOM   4139 O OE2   . GLU A 1 530 ? 154.621 195.506 173.434 1.00 83.12  ? 535 GLU M OE2   1 
ATOM   4140 N N     . GLU A 1 531 ? 160.666 196.675 171.031 1.00 72.98  ? 536 GLU M N     1 
ATOM   4141 C CA    . GLU A 1 531 ? 162.118 196.618 170.980 1.00 72.98  ? 536 GLU M CA    1 
ATOM   4142 C C     . GLU A 1 531 ? 162.692 197.828 170.266 1.00 72.98  ? 536 GLU M C     1 
ATOM   4143 O O     . GLU A 1 531 ? 163.713 198.379 170.686 1.00 72.98  ? 536 GLU M O     1 
ATOM   4144 C CB    . GLU A 1 531 ? 162.562 195.341 170.284 1.00 72.98  ? 536 GLU M CB    1 
ATOM   4145 C CG    . GLU A 1 531 ? 163.907 195.463 169.649 1.00 72.98  ? 536 GLU M CG    1 
ATOM   4146 C CD    . GLU A 1 531 ? 164.452 194.141 169.216 1.00 72.98  ? 536 GLU M CD    1 
ATOM   4147 O OE1   . GLU A 1 531 ? 163.975 193.105 169.717 1.00 72.98  ? 536 GLU M OE1   1 
ATOM   4148 O OE2   . GLU A 1 531 ? 165.367 194.129 168.373 1.00 72.98  ? 536 GLU M OE2   1 
ATOM   4149 N N     . GLU A 1 532 ? 162.043 198.271 169.195 1.00 76.80  ? 537 GLU M N     1 
ATOM   4150 C CA    . GLU A 1 532 ? 162.590 199.372 168.422 1.00 76.80  ? 537 GLU M CA    1 
ATOM   4151 C C     . GLU A 1 532 ? 162.475 200.686 169.173 1.00 76.80  ? 537 GLU M C     1 
ATOM   4152 O O     . GLU A 1 532 ? 163.374 201.526 169.097 1.00 76.80  ? 537 GLU M O     1 
ATOM   4153 C CB    . GLU A 1 532 ? 161.891 199.454 167.072 1.00 76.80  ? 537 GLU M CB    1 
ATOM   4154 C CG    . GLU A 1 532 ? 162.821 199.804 165.939 1.00 76.80  ? 537 GLU M CG    1 
ATOM   4155 C CD    . GLU A 1 532 ? 163.981 198.839 165.824 1.00 76.80  ? 537 GLU M CD    1 
ATOM   4156 O OE1   . GLU A 1 532 ? 163.803 197.654 166.155 1.00 76.80  ? 537 GLU M OE1   1 
ATOM   4157 O OE2   . GLU A 1 532 ? 165.074 199.264 165.401 1.00 76.80  ? 537 GLU M OE2   1 
ATOM   4158 N N     . CYS A 1 533 ? 161.387 200.895 169.899 1.00 75.83  ? 538 CYS M N     1 
ATOM   4159 C CA    . CYS A 1 533 ? 161.340 202.119 170.685 1.00 75.83  ? 538 CYS M CA    1 
ATOM   4160 C C     . CYS A 1 533 ? 162.167 202.017 171.957 1.00 75.83  ? 538 CYS M C     1 
ATOM   4161 O O     . CYS A 1 533 ? 162.321 203.019 172.659 1.00 75.83  ? 538 CYS M O     1 
ATOM   4162 C CB    . CYS A 1 533 ? 159.897 202.518 171.012 1.00 75.83  ? 538 CYS M CB    1 
ATOM   4163 S SG    . CYS A 1 533 ? 158.833 201.237 171.654 1.00 75.83  ? 538 CYS M SG    1 
ATOM   4164 N N     . MET A 1 534 ? 162.705 200.839 172.267 1.00 72.08  ? 539 MET M N     1 
ATOM   4165 C CA    . MET A 1 534 ? 163.702 200.716 173.327 1.00 72.08  ? 539 MET M CA    1 
ATOM   4166 C C     . MET A 1 534 ? 165.131 200.922 172.844 1.00 72.08  ? 539 MET M C     1 
ATOM   4167 O O     . MET A 1 534 ? 165.956 201.440 173.598 1.00 72.08  ? 539 MET M O     1 
ATOM   4168 C CB    . MET A 1 534 ? 163.596 199.342 173.993 1.00 72.08  ? 539 MET M CB    1 
ATOM   4169 C CG    . MET A 1 534 ? 163.718 199.374 175.496 1.00 72.08  ? 539 MET M CG    1 
ATOM   4170 S SD    . MET A 1 534 ? 162.685 200.654 176.229 1.00 72.08  ? 539 MET M SD    1 
ATOM   4171 C CE    . MET A 1 534 ? 161.061 200.188 175.619 1.00 72.08  ? 539 MET M CE    1 
ATOM   4172 N N     . PHE A 1 535 ? 165.433 200.541 171.605 1.00 62.37  ? 540 PHE M N     1 
ATOM   4173 C CA    . PHE A 1 535 ? 166.783 200.626 171.071 1.00 62.37  ? 540 PHE M CA    1 
ATOM   4174 C C     . PHE A 1 535 ? 167.257 202.079 170.986 1.00 62.37  ? 540 PHE M C     1 
ATOM   4175 O O     . PHE A 1 535 ? 166.443 203.000 170.910 1.00 62.37  ? 540 PHE M O     1 
ATOM   4176 C CB    . PHE A 1 535 ? 166.828 199.982 169.693 1.00 62.37  ? 540 PHE M CB    1 
ATOM   4177 C CG    . PHE A 1 535 ? 168.179 199.504 169.299 1.00 62.37  ? 540 PHE M CG    1 
ATOM   4178 C CD1   . PHE A 1 535 ? 168.711 198.370 169.864 1.00 62.37  ? 540 PHE M CD1   1 
ATOM   4179 C CD2   . PHE A 1 535 ? 168.923 200.194 168.366 1.00 62.37  ? 540 PHE M CD2   1 
ATOM   4180 C CE1   . PHE A 1 535 ? 169.957 197.937 169.507 1.00 62.37  ? 540 PHE M CE1   1 
ATOM   4181 C CE2   . PHE A 1 535 ? 170.167 199.761 168.007 1.00 62.37  ? 540 PHE M CE2   1 
ATOM   4182 C CZ    . PHE A 1 535 ? 170.686 198.633 168.578 1.00 62.37  ? 540 PHE M CZ    1 
ATOM   4183 N N     . PRO A 1 536 ? 168.581 202.312 171.013 1.00 59.48  ? 541 PRO M N     1 
ATOM   4184 C CA    . PRO A 1 536 ? 169.095 203.687 171.041 1.00 59.48  ? 541 PRO M CA    1 
ATOM   4185 C C     . PRO A 1 536 ? 168.682 204.630 169.918 1.00 59.48  ? 541 PRO M C     1 
ATOM   4186 O O     . PRO A 1 536 ? 168.021 205.638 170.190 1.00 59.48  ? 541 PRO M O     1 
ATOM   4187 C CB    . PRO A 1 536 ? 170.607 203.463 171.009 1.00 59.48  ? 541 PRO M CB    1 
ATOM   4188 C CG    . PRO A 1 536 ? 170.789 202.238 171.778 1.00 59.48  ? 541 PRO M CG    1 
ATOM   4189 C CD    . PRO A 1 536 ? 169.598 201.367 171.503 1.00 59.48  ? 541 PRO M CD    1 
ATOM   4190 N N     . LYS A 1 537 ? 169.043 204.348 168.671 1.00 61.79  ? 542 LYS M N     1 
ATOM   4191 C CA    . LYS A 1 537 ? 168.867 205.320 167.597 1.00 61.79  ? 542 LYS M CA    1 
ATOM   4192 C C     . LYS A 1 537 ? 167.912 204.809 166.532 1.00 61.79  ? 542 LYS M C     1 
ATOM   4193 O O     . LYS A 1 537 ? 168.146 204.979 165.338 1.00 61.79  ? 542 LYS M O     1 
ATOM   4194 C CB    . LYS A 1 537 ? 170.202 205.678 166.954 1.00 61.79  ? 542 LYS M CB    1 
ATOM   4195 C CG    . LYS A 1 537 ? 171.116 206.502 167.805 1.00 61.79  ? 542 LYS M CG    1 
ATOM   4196 C CD    . LYS A 1 537 ? 170.672 207.926 167.858 1.00 61.79  ? 542 LYS M CD    1 
ATOM   4197 C CE    . LYS A 1 537 ? 171.735 208.780 168.491 1.00 61.79  ? 542 LYS M CE    1 
ATOM   4198 N NZ    . LYS A 1 537 ? 171.348 210.208 168.486 1.00 61.79  ? 542 LYS M NZ    1 
ATOM   4199 N N     . ALA A 1 538 ? 166.821 204.181 166.946 1.00 71.13  ? 543 ALA M N     1 
ATOM   4200 C CA    . ALA A 1 538 ? 165.947 203.534 165.985 1.00 71.13  ? 543 ALA M CA    1 
ATOM   4201 C C     . ALA A 1 538 ? 165.171 204.563 165.175 1.00 71.13  ? 543 ALA M C     1 
ATOM   4202 O O     . ALA A 1 538 ? 164.865 205.659 165.647 1.00 71.13  ? 543 ALA M O     1 
ATOM   4203 C CB    . ALA A 1 538 ? 164.986 202.589 166.692 1.00 71.13  ? 543 ALA M CB    1 
ATOM   4204 N N     . THR A 1 539 ? 164.855 204.193 163.937 1.00 80.19  ? 544 THR M N     1 
ATOM   4205 C CA    . THR A 1 539 ? 164.138 205.054 163.012 1.00 80.19  ? 544 THR M CA    1 
ATOM   4206 C C     . THR A 1 539 ? 163.089 204.202 162.308 1.00 80.19  ? 544 THR M C     1 
ATOM   4207 O O     . THR A 1 539 ? 163.082 202.975 162.426 1.00 80.19  ? 544 THR M O     1 
ATOM   4208 C CB    . THR A 1 539 ? 165.104 205.713 162.008 1.00 80.19  ? 544 THR M CB    1 
ATOM   4209 O OG1   . THR A 1 539 ? 166.183 206.321 162.721 1.00 80.19  ? 544 THR M OG1   1 
ATOM   4210 C CG2   . THR A 1 539 ? 164.425 206.808 161.218 1.00 80.19  ? 544 THR M CG2   1 
ATOM   4211 N N     . ASP A 1 540 ? 162.186 204.864 161.586 1.00 85.55  ? 545 ASP M N     1 
ATOM   4212 C CA    . ASP A 1 540 ? 161.106 204.150 160.916 1.00 85.55  ? 545 ASP M CA    1 
ATOM   4213 C C     . ASP A 1 540 ? 161.638 203.223 159.832 1.00 85.55  ? 545 ASP M C     1 
ATOM   4214 O O     . ASP A 1 540 ? 161.110 202.124 159.633 1.00 85.55  ? 545 ASP M O     1 
ATOM   4215 C CB    . ASP A 1 540 ? 160.111 205.147 160.335 1.00 85.55  ? 545 ASP M CB    1 
ATOM   4216 C CG    . ASP A 1 540 ? 159.629 206.142 161.363 1.00 85.55  ? 545 ASP M CG    1 
ATOM   4217 O OD1   . ASP A 1 540 ? 159.719 205.832 162.567 1.00 85.55  ? 545 ASP M OD1   1 
ATOM   4218 O OD2   . ASP A 1 540 ? 159.163 207.232 160.973 1.00 85.55  ? 545 ASP M OD2   1 
ATOM   4219 N N     . MET A 1 541 ? 162.680 203.645 159.119 1.00 85.43  ? 546 MET M N     1 
ATOM   4220 C CA    . MET A 1 541 ? 163.246 202.774 158.098 1.00 85.43  ? 546 MET M CA    1 
ATOM   4221 C C     . MET A 1 541 ? 163.848 201.523 158.719 1.00 85.43  ? 546 MET M C     1 
ATOM   4222 O O     . MET A 1 541 ? 163.713 200.424 158.172 1.00 85.43  ? 546 MET M O     1 
ATOM   4223 C CB    . MET A 1 541 ? 164.285 203.536 157.283 1.00 85.43  ? 546 MET M CB    1 
ATOM   4224 C CG    . MET A 1 541 ? 163.718 204.739 156.540 1.00 85.43  ? 546 MET M CG    1 
ATOM   4225 S SD    . MET A 1 541 ? 162.858 204.325 155.003 1.00 85.43  ? 546 MET M SD    1 
ATOM   4226 C CE    . MET A 1 541 ? 161.158 204.205 155.546 1.00 85.43  ? 546 MET M CE    1 
ATOM   4227 N N     . THR A 1 542 ? 164.502 201.667 159.874 1.00 82.35  ? 547 THR M N     1 
ATOM   4228 C CA    . THR A 1 542 ? 165.044 200.508 160.575 1.00 82.35  ? 547 THR M CA    1 
ATOM   4229 C C     . THR A 1 542 ? 163.934 199.599 161.079 1.00 82.35  ? 547 THR M C     1 
ATOM   4230 O O     . THR A 1 542 ? 164.055 198.371 161.029 1.00 82.35  ? 547 THR M O     1 
ATOM   4231 C CB    . THR A 1 542 ? 165.913 200.965 161.737 1.00 82.35  ? 547 THR M CB    1 
ATOM   4232 O OG1   . THR A 1 542 ? 165.100 201.670 162.677 1.00 82.35  ? 547 THR M OG1   1 
ATOM   4233 C CG2   . THR A 1 542 ? 166.994 201.890 161.241 1.00 82.35  ? 547 THR M CG2   1 
ATOM   4234 N N     . PHE A 1 543 ? 162.855 200.190 161.584 1.00 82.21  ? 548 PHE M N     1 
ATOM   4235 C CA    . PHE A 1 543 ? 161.686 199.413 161.971 1.00 82.21  ? 548 PHE M CA    1 
ATOM   4236 C C     . PHE A 1 543 ? 161.170 198.588 160.799 1.00 82.21  ? 548 PHE M C     1 
ATOM   4237 O O     . PHE A 1 543 ? 160.912 197.384 160.932 1.00 82.21  ? 548 PHE M O     1 
ATOM   4238 C CB    . PHE A 1 543 ? 160.610 200.361 162.491 1.00 82.21  ? 548 PHE M CB    1 
ATOM   4239 C CG    . PHE A 1 543 ? 159.360 199.680 162.932 1.00 82.21  ? 548 PHE M CG    1 
ATOM   4240 C CD1   . PHE A 1 543 ? 159.393 198.410 163.460 1.00 82.21  ? 548 PHE M CD1   1 
ATOM   4241 C CD2   . PHE A 1 543 ? 158.146 200.316 162.817 1.00 82.21  ? 548 PHE M CD2   1 
ATOM   4242 C CE1   . PHE A 1 543 ? 158.242 197.789 163.858 1.00 82.21  ? 548 PHE M CE1   1 
ATOM   4243 C CE2   . PHE A 1 543 ? 156.994 199.698 163.216 1.00 82.21  ? 548 PHE M CE2   1 
ATOM   4244 C CZ    . PHE A 1 543 ? 157.041 198.433 163.738 1.00 82.21  ? 548 PHE M CZ    1 
ATOM   4245 N N     . LYS A 1 544 ? 161.010 199.225 159.640 1.00 83.70  ? 549 LYS M N     1 
ATOM   4246 C CA    . LYS A 1 544 ? 160.542 198.512 158.458 1.00 83.70  ? 549 LYS M CA    1 
ATOM   4247 C C     . LYS A 1 544 ? 161.507 197.400 158.072 1.00 83.70  ? 549 LYS M C     1 
ATOM   4248 O O     . LYS A 1 544 ? 161.085 196.283 157.740 1.00 83.70  ? 549 LYS M O     1 
ATOM   4249 C CB    . LYS A 1 544 ? 160.363 199.488 157.296 1.00 83.70  ? 549 LYS M CB    1 
ATOM   4250 C CG    . LYS A 1 544 ? 160.454 198.823 155.935 1.00 83.70  ? 549 LYS M CG    1 
ATOM   4251 C CD    . LYS A 1 544 ? 160.743 199.806 154.822 1.00 83.70  ? 549 LYS M CD    1 
ATOM   4252 C CE    . LYS A 1 544 ? 161.138 199.075 153.550 1.00 83.70  ? 549 LYS M CE    1 
ATOM   4253 N NZ    . LYS A 1 544 ? 161.391 200.013 152.434 1.00 83.70  ? 549 LYS M NZ    1 
ATOM   4254 N N     . ALA A 1 545 ? 162.807 197.692 158.102 1.00 82.91  ? 550 ALA M N     1 
ATOM   4255 C CA    . ALA A 1 545 ? 163.804 196.693 157.744 1.00 82.91  ? 550 ALA M CA    1 
ATOM   4256 C C     . ALA A 1 545 ? 163.737 195.492 158.669 1.00 82.91  ? 550 ALA M C     1 
ATOM   4257 O O     . ALA A 1 545 ? 163.876 194.354 158.222 1.00 82.91  ? 550 ALA M O     1 
ATOM   4258 C CB    . ALA A 1 545 ? 165.197 197.310 157.776 1.00 82.91  ? 550 ALA M CB    1 
ATOM   4259 N N     . LYS A 1 546 ? 163.529 195.723 159.964 1.00 81.20  ? 551 LYS M N     1 
ATOM   4260 C CA    . LYS A 1 546 ? 163.446 194.605 160.897 1.00 81.20  ? 551 LYS M CA    1 
ATOM   4261 C C     . LYS A 1 546 ? 162.178 193.798 160.674 1.00 81.20  ? 551 LYS M C     1 
ATOM   4262 O O     . LYS A 1 546 ? 162.213 192.561 160.695 1.00 81.20  ? 551 LYS M O     1 
ATOM   4263 C CB    . LYS A 1 546 ? 163.515 195.104 162.335 1.00 81.20  ? 551 LYS M CB    1 
ATOM   4264 C CG    . LYS A 1 546 ? 164.875 195.634 162.716 1.00 81.20  ? 551 LYS M CG    1 
ATOM   4265 C CD    . LYS A 1 546 ? 165.081 195.611 164.209 1.00 81.20  ? 551 LYS M CD    1 
ATOM   4266 C CE    . LYS A 1 546 ? 165.040 194.205 164.746 1.00 81.20  ? 551 LYS M CE    1 
ATOM   4267 N NZ    . LYS A 1 546 ? 165.492 194.177 166.154 1.00 81.20  ? 551 LYS M NZ    1 
ATOM   4268 N N     . LEU A 1 547 ? 161.053 194.477 160.449 1.00 85.69  ? 552 LEU M N     1 
ATOM   4269 C CA    . LEU A 1 547 ? 159.824 193.767 160.113 1.00 85.69  ? 552 LEU M CA    1 
ATOM   4270 C C     . LEU A 1 547 ? 160.040 192.842 158.926 1.00 85.69  ? 552 LEU M C     1 
ATOM   4271 O O     . LEU A 1 547 ? 159.690 191.656 158.970 1.00 85.69  ? 552 LEU M O     1 
ATOM   4272 C CB    . LEU A 1 547 ? 158.707 194.763 159.815 1.00 85.69  ? 552 LEU M CB    1 
ATOM   4273 C CG    . LEU A 1 547 ? 157.951 195.262 161.039 1.00 85.69  ? 552 LEU M CG    1 
ATOM   4274 C CD1   . LEU A 1 547 ? 156.948 196.322 160.655 1.00 85.69  ? 552 LEU M CD1   1 
ATOM   4275 C CD2   . LEU A 1 547 ? 157.271 194.100 161.725 1.00 85.69  ? 552 LEU M CD2   1 
ATOM   4276 N N     . PHE A 1 548 ? 160.639 193.366 157.858 1.00 88.34  ? 553 PHE M N     1 
ATOM   4277 C CA    . PHE A 1 548 ? 160.834 192.560 156.661 1.00 88.34  ? 553 PHE M CA    1 
ATOM   4278 C C     . PHE A 1 548 ? 161.823 191.431 156.911 1.00 88.34  ? 553 PHE M C     1 
ATOM   4279 O O     . PHE A 1 548 ? 161.534 190.268 156.613 1.00 88.34  ? 553 PHE M O     1 
ATOM   4280 C CB    . PHE A 1 548 ? 161.289 193.445 155.510 1.00 88.34  ? 553 PHE M CB    1 
ATOM   4281 C CG    . PHE A 1 548 ? 160.184 194.248 154.913 1.00 88.34  ? 553 PHE M CG    1 
ATOM   4282 C CD1   . PHE A 1 548 ? 158.896 193.763 154.916 1.00 88.34  ? 553 PHE M CD1   1 
ATOM   4283 C CD2   . PHE A 1 548 ? 160.421 195.494 154.374 1.00 88.34  ? 553 PHE M CD2   1 
ATOM   4284 C CE1   . PHE A 1 548 ? 157.869 194.491 154.382 1.00 88.34  ? 553 PHE M CE1   1 
ATOM   4285 C CE2   . PHE A 1 548 ? 159.392 196.227 153.835 1.00 88.34  ? 553 PHE M CE2   1 
ATOM   4286 C CZ    . PHE A 1 548 ? 158.117 195.727 153.840 1.00 88.34  ? 553 PHE M CZ    1 
ATOM   4287 N N     . ASP A 1 549 ? 162.984 191.751 157.482 1.00 88.45  ? 554 ASP M N     1 
ATOM   4288 C CA    . ASP A 1 549 ? 163.998 190.737 157.733 1.00 88.45  ? 554 ASP M CA    1 
ATOM   4289 C C     . ASP A 1 549 ? 163.465 189.606 158.590 1.00 88.45  ? 554 ASP M C     1 
ATOM   4290 O O     . ASP A 1 549 ? 163.912 188.463 158.457 1.00 88.45  ? 554 ASP M O     1 
ATOM   4291 C CB    . ASP A 1 549 ? 165.211 191.368 158.413 1.00 88.45  ? 554 ASP M CB    1 
ATOM   4292 C CG    . ASP A 1 549 ? 166.228 191.882 157.426 1.00 88.45  ? 554 ASP M CG    1 
ATOM   4293 O OD1   . ASP A 1 549 ? 165.935 191.887 156.213 1.00 88.45  ? 554 ASP M OD1   1 
ATOM   4294 O OD2   . ASP A 1 549 ? 167.328 192.279 157.863 1.00 88.45  ? 554 ASP M OD2   1 
ATOM   4295 N N     . ASN A 1 550 ? 162.507 189.890 159.461 1.00 88.89  ? 555 ASN M N     1 
ATOM   4296 C CA    . ASN A 1 550 ? 162.076 188.886 160.410 1.00 88.89  ? 555 ASN M CA    1 
ATOM   4297 C C     . ASN A 1 550 ? 160.758 188.224 160.028 1.00 88.89  ? 555 ASN M C     1 
ATOM   4298 O O     . ASN A 1 550 ? 160.394 187.217 160.640 1.00 88.89  ? 555 ASN M O     1 
ATOM   4299 C CB    . ASN A 1 550 ? 161.968 189.520 161.797 1.00 88.89  ? 555 ASN M CB    1 
ATOM   4300 C CG    . ASN A 1 550 ? 162.043 188.512 162.902 1.00 88.89  ? 555 ASN M CG    1 
ATOM   4301 O OD1   . ASN A 1 550 ? 162.154 187.314 162.666 1.00 88.89  ? 555 ASN M OD1   1 
ATOM   4302 N ND2   . ASN A 1 550 ? 162.008 188.994 164.130 1.00 88.89  ? 555 ASN M ND2   1 
ATOM   4303 N N     . HIS A 1 551 ? 160.038 188.741 159.031 1.00 91.70  ? 556 HIS M N     1 
ATOM   4304 C CA    . HIS A 1 551 ? 158.778 188.095 158.681 1.00 91.70  ? 556 HIS M CA    1 
ATOM   4305 C C     . HIS A 1 551 ? 158.617 187.753 157.204 1.00 91.70  ? 556 HIS M C     1 
ATOM   4306 O O     . HIS A 1 551 ? 157.955 186.767 156.871 1.00 91.70  ? 556 HIS M O     1 
ATOM   4307 C CB    . HIS A 1 551 ? 157.618 188.978 159.125 1.00 91.70  ? 556 HIS M CB    1 
ATOM   4308 C CG    . HIS A 1 551 ? 157.462 189.052 160.607 1.00 91.70  ? 556 HIS M CG    1 
ATOM   4309 N ND1   . HIS A 1 551 ? 157.018 187.986 161.357 1.00 91.70  ? 556 HIS M ND1   1 
ATOM   4310 C CD2   . HIS A 1 551 ? 157.701 190.055 161.481 1.00 91.70  ? 556 HIS M CD2   1 
ATOM   4311 C CE1   . HIS A 1 551 ? 156.983 188.332 162.630 1.00 91.70  ? 556 HIS M CE1   1 
ATOM   4312 N NE2   . HIS A 1 551 ? 157.396 189.582 162.733 1.00 91.70  ? 556 HIS M NE2   1 
ATOM   4313 N N     . LEU A 1 552 ? 159.215 188.544 156.318 1.00 92.82  ? 557 LEU M N     1 
ATOM   4314 C CA    . LEU A 1 552 ? 158.929 188.438 154.891 1.00 92.82  ? 557 LEU M CA    1 
ATOM   4315 C C     . LEU A 1 552 ? 159.218 187.041 154.368 1.00 92.82  ? 557 LEU M C     1 
ATOM   4316 O O     . LEU A 1 552 ? 160.358 186.573 154.413 1.00 92.82  ? 557 LEU M O     1 
ATOM   4317 C CB    . LEU A 1 552 ? 159.754 189.455 154.117 1.00 92.82  ? 557 LEU M CB    1 
ATOM   4318 C CG    . LEU A 1 552 ? 159.308 189.626 152.675 1.00 92.82  ? 557 LEU M CG    1 
ATOM   4319 C CD1   . LEU A 1 552 ? 158.151 190.604 152.621 1.00 92.82  ? 557 LEU M CD1   1 
ATOM   4320 C CD2   . LEU A 1 552 ? 160.462 190.093 151.813 1.00 92.82  ? 557 LEU M CD2   1 
ATOM   4321 N N     . GLY A 1 553 ? 158.181 186.377 153.868 1.00 94.89  ? 558 GLY M N     1 
ATOM   4322 C CA    . GLY A 1 553 ? 158.339 185.056 153.300 1.00 94.89  ? 558 GLY M CA    1 
ATOM   4323 C C     . GLY A 1 553 ? 158.351 183.966 154.346 1.00 94.89  ? 558 GLY M C     1 
ATOM   4324 O O     . GLY A 1 553 ? 157.718 182.923 154.172 1.00 94.89  ? 558 GLY M O     1 
ATOM   4325 N N     . LYS A 1 554 ? 159.065 184.203 155.447 1.00 96.00  ? 559 LYS M N     1 
ATOM   4326 C CA    . LYS A 1 554 ? 159.106 183.239 156.539 1.00 96.00  ? 559 LYS M CA    1 
ATOM   4327 C C     . LYS A 1 554 ? 157.758 183.100 157.225 1.00 96.00  ? 559 LYS M C     1 
ATOM   4328 O O     . LYS A 1 554 ? 157.522 182.095 157.901 1.00 96.00  ? 559 LYS M O     1 
ATOM   4329 C CB    . LYS A 1 554 ? 160.171 183.655 157.550 1.00 96.00  ? 559 LYS M CB    1 
ATOM   4330 C CG    . LYS A 1 554 ? 161.400 184.243 156.894 1.00 96.00  ? 559 LYS M CG    1 
ATOM   4331 C CD    . LYS A 1 554 ? 162.373 184.804 157.901 1.00 96.00  ? 559 LYS M CD    1 
ATOM   4332 C CE    . LYS A 1 554 ? 163.532 185.474 157.193 1.00 96.00  ? 559 LYS M CE    1 
ATOM   4333 N NZ    . LYS A 1 554 ? 164.553 185.985 158.148 1.00 96.00  ? 559 LYS M NZ    1 
ATOM   4334 N N     . SER A 1 555 ? 156.879 184.083 157.067 1.00 97.88  ? 560 SER M N     1 
ATOM   4335 C CA    . SER A 1 555 ? 155.522 184.048 157.589 1.00 97.88  ? 560 SER M CA    1 
ATOM   4336 C C     . SER A 1 555 ? 154.561 183.642 156.481 1.00 97.88  ? 560 SER M C     1 
ATOM   4337 O O     . SER A 1 555 ? 154.962 183.349 155.352 1.00 97.88  ? 560 SER M O     1 
ATOM   4338 C CB    . SER A 1 555 ? 155.121 185.409 158.160 1.00 97.88  ? 560 SER M CB    1 
ATOM   4339 O OG    . SER A 1 555 ? 154.550 186.213 157.147 1.00 97.88  ? 560 SER M OG    1 
ATOM   4340 N N     . ALA A 1 556 ? 153.273 183.617 156.817 1.00 99.33  ? 561 ALA M N     1 
ATOM   4341 C CA    . ALA A 1 556 ? 152.250 183.261 155.845 1.00 99.33  ? 561 ALA M CA    1 
ATOM   4342 C C     . ALA A 1 556 ? 151.355 184.424 155.445 1.00 99.33  ? 561 ALA M C     1 
ATOM   4343 O O     . ALA A 1 556 ? 150.978 184.516 154.273 1.00 99.33  ? 561 ALA M O     1 
ATOM   4344 C CB    . ALA A 1 556 ? 151.381 182.121 156.387 1.00 99.33  ? 561 ALA M CB    1 
ATOM   4345 N N     . ASN A 1 557 ? 151.021 185.317 156.376 1.00 102.08 ? 562 ASN M N     1 
ATOM   4346 C CA    . ASN A 1 557 ? 150.114 186.423 156.106 1.00 102.08 ? 562 ASN M CA    1 
ATOM   4347 C C     . ASN A 1 557 ? 150.821 187.742 155.862 1.00 102.08 ? 562 ASN M C     1 
ATOM   4348 O O     . ASN A 1 557 ? 150.281 188.593 155.157 1.00 102.08 ? 562 ASN M O     1 
ATOM   4349 C CB    . ASN A 1 557 ? 149.136 186.609 157.270 1.00 102.08 ? 562 ASN M CB    1 
ATOM   4350 C CG    . ASN A 1 557 ? 148.481 185.316 157.695 1.00 102.08 ? 562 ASN M CG    1 
ATOM   4351 O OD1   . ASN A 1 557 ? 148.768 184.787 158.767 1.00 102.08 ? 562 ASN M OD1   1 
ATOM   4352 N ND2   . ASN A 1 557 ? 147.584 184.806 156.864 1.00 102.08 ? 562 ASN M ND2   1 
ATOM   4353 N N     . PHE A 1 558 ? 151.998 187.939 156.439 1.00 97.46  ? 563 PHE M N     1 
ATOM   4354 C CA    . PHE A 1 558 ? 152.754 189.157 156.195 1.00 97.46  ? 563 PHE M CA    1 
ATOM   4355 C C     . PHE A 1 558 ? 153.261 189.158 154.763 1.00 97.46  ? 563 PHE M C     1 
ATOM   4356 O O     . PHE A 1 558 ? 153.766 188.144 154.276 1.00 97.46  ? 563 PHE M O     1 
ATOM   4357 C CB    . PHE A 1 558 ? 153.918 189.254 157.177 1.00 97.46  ? 563 PHE M CB    1 
ATOM   4358 C CG    . PHE A 1 558 ? 154.703 190.517 157.063 1.00 97.46  ? 563 PHE M CG    1 
ATOM   4359 C CD1   . PHE A 1 558 ? 154.434 191.584 157.887 1.00 97.46  ? 563 PHE M CD1   1 
ATOM   4360 C CD2   . PHE A 1 558 ? 155.720 190.634 156.142 1.00 97.46  ? 563 PHE M CD2   1 
ATOM   4361 C CE1   . PHE A 1 558 ? 155.153 192.736 157.787 1.00 97.46  ? 563 PHE M CE1   1 
ATOM   4362 C CE2   . PHE A 1 558 ? 156.436 191.789 156.040 1.00 97.46  ? 563 PHE M CE2   1 
ATOM   4363 C CZ    . PHE A 1 558 ? 156.153 192.842 156.863 1.00 97.46  ? 563 PHE M CZ    1 
ATOM   4364 N N     . GLN A 1 559 ? 153.132 190.293 154.085 1.00 100.74 ? 564 GLN M N     1 
ATOM   4365 C CA    . GLN A 1 559 ? 153.528 190.354 152.687 1.00 100.74 ? 564 GLN M CA    1 
ATOM   4366 C C     . GLN A 1 559 ? 153.675 191.806 152.260 1.00 100.74 ? 564 GLN M C     1 
ATOM   4367 O O     . GLN A 1 559 ? 153.334 192.731 152.999 1.00 100.74 ? 564 GLN M O     1 
ATOM   4368 C CB    . GLN A 1 559 ? 152.517 189.614 151.822 1.00 100.74 ? 564 GLN M CB    1 
ATOM   4369 C CG    . GLN A 1 559 ? 151.154 190.215 151.919 1.00 100.74 ? 564 GLN M CG    1 
ATOM   4370 C CD    . GLN A 1 559 ? 150.116 189.362 151.266 1.00 100.74 ? 564 GLN M CD    1 
ATOM   4371 O OE1   . GLN A 1 559 ? 150.418 188.300 150.727 1.00 100.74 ? 564 GLN M OE1   1 
ATOM   4372 N NE2   . GLN A 1 559 ? 148.875 189.821 151.301 1.00 100.74 ? 564 GLN M NE2   1 
ATOM   4373 N N     . LYS A 1 560 ? 154.189 191.986 151.041 1.00 101.80 ? 565 LYS M N     1 
ATOM   4374 C CA    . LYS A 1 560 ? 154.492 193.303 150.510 1.00 101.80 ? 565 LYS M CA    1 
ATOM   4375 C C     . LYS A 1 560 ? 153.249 194.190 150.493 1.00 101.80 ? 565 LYS M C     1 
ATOM   4376 O O     . LYS A 1 560 ? 152.123 193.699 150.580 1.00 101.80 ? 565 LYS M O     1 
ATOM   4377 C CB    . LYS A 1 560 ? 155.058 193.178 149.096 1.00 101.80 ? 565 LYS M CB    1 
ATOM   4378 C CG    . LYS A 1 560 ? 156.500 192.722 149.037 1.00 101.80 ? 565 LYS M CG    1 
ATOM   4379 C CD    . LYS A 1 560 ? 157.407 193.720 149.734 1.00 101.80 ? 565 LYS M CD    1 
ATOM   4380 C CE    . LYS A 1 560 ? 158.885 193.387 149.543 1.00 101.80 ? 565 LYS M CE    1 
ATOM   4381 N NZ    . LYS A 1 560 ? 159.354 193.616 148.150 1.00 101.80 ? 565 LYS M NZ    1 
ATOM   4382 N N     . PRO A 1 561 ? 153.429 195.501 150.392 1.00 104.19 ? 566 PRO M N     1 
ATOM   4383 C CA    . PRO A 1 561 ? 152.294 196.399 150.181 1.00 104.19 ? 566 PRO M CA    1 
ATOM   4384 C C     . PRO A 1 561 ? 151.859 196.360 148.721 1.00 104.19 ? 566 PRO M C     1 
ATOM   4385 O O     . PRO A 1 561 ? 152.440 195.667 147.889 1.00 104.19 ? 566 PRO M O     1 
ATOM   4386 C CB    . PRO A 1 561 ? 152.863 197.764 150.552 1.00 104.19 ? 566 PRO M CB    1 
ATOM   4387 C CG    . PRO A 1 561 ? 154.282 197.657 150.187 1.00 104.19 ? 566 PRO M CG    1 
ATOM   4388 C CD    . PRO A 1 561 ? 154.685 196.255 150.537 1.00 104.19 ? 566 PRO M CD    1 
ATOM   4389 N N     . ARG A 1 562 ? 150.818 197.129 148.420 1.00 112.20 ? 567 ARG M N     1 
ATOM   4390 C CA    . ARG A 1 562 ? 150.342 197.286 147.055 1.00 112.20 ? 567 ARG M CA    1 
ATOM   4391 C C     . ARG A 1 562 ? 150.050 198.754 146.799 1.00 112.20 ? 567 ARG M C     1 
ATOM   4392 O O     . ARG A 1 562 ? 149.512 199.447 147.665 1.00 112.20 ? 567 ARG M O     1 
ATOM   4393 C CB    . ARG A 1 562 ? 149.093 196.443 146.795 1.00 112.20 ? 567 ARG M CB    1 
ATOM   4394 C CG    . ARG A 1 562 ? 148.115 196.427 147.945 1.00 112.20 ? 567 ARG M CG    1 
ATOM   4395 C CD    . ARG A 1 562 ? 147.005 195.424 147.689 1.00 112.20 ? 567 ARG M CD    1 
ATOM   4396 N NE    . ARG A 1 562 ? 146.157 195.222 148.861 1.00 112.20 ? 567 ARG M NE    1 
ATOM   4397 C CZ    . ARG A 1 562 ? 145.116 195.986 149.175 1.00 112.20 ? 567 ARG M CZ    1 
ATOM   4398 N NH1   . ARG A 1 562 ? 144.790 197.017 148.409 1.00 112.20 ? 567 ARG M NH1   1 
ATOM   4399 N NH2   . ARG A 1 562 ? 144.400 195.721 150.259 1.00 112.20 ? 567 ARG M NH2   1 
ATOM   4400 N N     . ASN A 1 563 ? 150.418 199.223 145.613 1.00 120.01 ? 568 ASN M N     1 
ATOM   4401 C CA    . ASN A 1 563 ? 150.196 200.604 145.200 1.00 120.01 ? 568 ASN M CA    1 
ATOM   4402 C C     . ASN A 1 563 ? 149.141 200.583 144.103 1.00 120.01 ? 568 ASN M C     1 
ATOM   4403 O O     . ASN A 1 563 ? 149.422 200.170 142.973 1.00 120.01 ? 568 ASN M O     1 
ATOM   4404 C CB    . ASN A 1 563 ? 151.499 201.240 144.718 1.00 120.01 ? 568 ASN M CB    1 
ATOM   4405 C CG    . ASN A 1 563 ? 151.330 202.686 144.265 1.00 120.01 ? 568 ASN M CG    1 
ATOM   4406 O OD1   . ASN A 1 563 ? 150.237 203.133 143.916 1.00 120.01 ? 568 ASN M OD1   1 
ATOM   4407 N ND2   . ASN A 1 563 ? 152.432 203.425 144.265 1.00 120.01 ? 568 ASN M ND2   1 
ATOM   4408 N N     . ILE A 1 564 ? 147.934 201.033 144.433 1.00 121.69 ? 569 ILE M N     1 
ATOM   4409 C CA    . ILE A 1 564 ? 146.805 201.015 143.514 1.00 121.69 ? 569 ILE M CA    1 
ATOM   4410 C C     . ILE A 1 564 ? 146.260 202.428 143.377 1.00 121.69 ? 569 ILE M C     1 
ATOM   4411 O O     . ILE A 1 564 ? 146.198 203.174 144.359 1.00 121.69 ? 569 ILE M O     1 
ATOM   4412 C CB    . ILE A 1 564 ? 145.701 200.051 143.994 1.00 121.69 ? 569 ILE M CB    1 
ATOM   4413 C CG1   . ILE A 1 564 ? 146.314 198.728 144.455 1.00 121.69 ? 569 ILE M CG1   1 
ATOM   4414 C CG2   . ILE A 1 564 ? 144.680 199.817 142.889 1.00 121.69 ? 569 ILE M CG2   1 
ATOM   4415 C CD1   . ILE A 1 564 ? 147.024 197.975 143.361 1.00 121.69 ? 569 ILE M CD1   1 
ATOM   4416 N N     . LYS A 1 565 ? 145.879 202.789 142.148 1.00 123.60 ? 570 LYS M N     1 
ATOM   4417 C CA    . LYS A 1 565 ? 145.237 204.071 141.822 1.00 123.60 ? 570 LYS M CA    1 
ATOM   4418 C C     . LYS A 1 565 ? 145.961 205.262 142.448 1.00 123.60 ? 570 LYS M C     1 
ATOM   4419 O O     . LYS A 1 565 ? 145.358 206.302 142.729 1.00 123.60 ? 570 LYS M O     1 
ATOM   4420 C CB    . LYS A 1 565 ? 143.747 204.062 142.202 1.00 123.60 ? 570 LYS M CB    1 
ATOM   4421 C CG    . LYS A 1 565 ? 143.402 204.156 143.693 1.00 123.60 ? 570 LYS M CG    1 
ATOM   4422 C CD    . LYS A 1 565 ? 142.126 203.380 143.999 1.00 123.60 ? 570 LYS M CD    1 
ATOM   4423 C CE    . LYS A 1 565 ? 141.584 203.689 145.385 1.00 123.60 ? 570 LYS M CE    1 
ATOM   4424 N NZ    . LYS A 1 565 ? 142.564 203.395 146.461 1.00 123.60 ? 570 LYS M NZ    1 
ATOM   4425 N N     . GLY A 1 566 ? 147.269 205.132 142.637 1.00 123.06 ? 571 GLY M N     1 
ATOM   4426 C CA    . GLY A 1 566 ? 148.040 206.210 143.228 1.00 123.06 ? 571 GLY M CA    1 
ATOM   4427 C C     . GLY A 1 566 ? 147.669 206.509 144.664 1.00 123.06 ? 571 GLY M C     1 
ATOM   4428 O O     . GLY A 1 566 ? 147.571 207.685 145.043 1.00 123.06 ? 571 GLY M O     1 
ATOM   4429 N N     . LYS A 1 567 ? 147.450 205.470 145.475 1.00 121.67 ? 572 LYS M N     1 
ATOM   4430 C CA    . LYS A 1 567 ? 147.185 205.655 146.891 1.00 121.67 ? 572 LYS M CA    1 
ATOM   4431 C C     . LYS A 1 567 ? 148.337 206.415 147.546 1.00 121.67 ? 572 LYS M C     1 
ATOM   4432 O O     . LYS A 1 567 ? 149.436 206.492 146.990 1.00 121.67 ? 572 LYS M O     1 
ATOM   4433 C CB    . LYS A 1 567 ? 146.990 204.303 147.572 1.00 121.67 ? 572 LYS M CB    1 
ATOM   4434 C CG    . LYS A 1 567 ? 145.569 203.774 147.543 1.00 121.67 ? 572 LYS M CG    1 
ATOM   4435 C CD    . LYS A 1 567 ? 145.501 202.444 148.268 1.00 121.67 ? 572 LYS M CD    1 
ATOM   4436 C CE    . LYS A 1 567 ? 146.215 202.536 149.615 1.00 121.67 ? 572 LYS M CE    1 
ATOM   4437 N NZ    . LYS A 1 567 ? 146.544 201.210 150.206 1.00 121.67 ? 572 LYS M NZ    1 
ATOM   4438 N N     . PRO A 1 568 ? 148.110 206.995 148.735 1.00 116.56 ? 573 PRO M N     1 
ATOM   4439 C CA    . PRO A 1 568 ? 149.164 207.803 149.367 1.00 116.56 ? 573 PRO M CA    1 
ATOM   4440 C C     . PRO A 1 568 ? 150.475 207.058 149.575 1.00 116.56 ? 573 PRO M C     1 
ATOM   4441 O O     . PRO A 1 568 ? 151.503 207.451 149.015 1.00 116.56 ? 573 PRO M O     1 
ATOM   4442 C CB    . PRO A 1 568 ? 148.540 208.207 150.712 1.00 116.56 ? 573 PRO M CB    1 
ATOM   4443 C CG    . PRO A 1 568 ? 147.347 207.305 150.891 1.00 116.56 ? 573 PRO M CG    1 
ATOM   4444 C CD    . PRO A 1 568 ? 146.858 207.039 149.509 1.00 116.56 ? 573 PRO M CD    1 
ATOM   4445 N N     . GLU A 1 569 ? 150.447 205.975 150.348 1.00 110.54 ? 574 GLU M N     1 
ATOM   4446 C CA    . GLU A 1 569 ? 151.659 205.243 150.696 1.00 110.54 ? 574 GLU M CA    1 
ATOM   4447 C C     . GLU A 1 569 ? 151.271 204.018 151.508 1.00 110.54 ? 574 GLU M C     1 
ATOM   4448 O O     . GLU A 1 569 ? 150.234 204.007 152.176 1.00 110.54 ? 574 GLU M O     1 
ATOM   4449 C CB    . GLU A 1 569 ? 152.632 206.120 151.495 1.00 110.54 ? 574 GLU M CB    1 
ATOM   4450 C CG    . GLU A 1 569 ? 153.994 205.503 151.749 1.00 110.54 ? 574 GLU M CG    1 
ATOM   4451 C CD    . GLU A 1 569 ? 154.971 205.736 150.615 1.00 110.54 ? 574 GLU M CD    1 
ATOM   4452 O OE1   . GLU A 1 569 ? 154.857 206.774 149.933 1.00 110.54 ? 574 GLU M OE1   1 
ATOM   4453 O OE2   . GLU A 1 569 ? 155.856 204.882 150.410 1.00 110.54 ? 574 GLU M OE2   1 
ATOM   4454 N N     . ALA A 1 570 ? 152.113 202.992 151.442 1.00 104.35 ? 575 ALA M N     1 
ATOM   4455 C CA    . ALA A 1 570 ? 151.966 201.816 152.283 1.00 104.35 ? 575 ALA M CA    1 
ATOM   4456 C C     . ALA A 1 570 ? 153.321 201.145 152.403 1.00 104.35 ? 575 ALA M C     1 
ATOM   4457 O O     . ALA A 1 570 ? 154.036 200.993 151.410 1.00 104.35 ? 575 ALA M O     1 
ATOM   4458 C CB    . ALA A 1 570 ? 150.940 200.832 151.719 1.00 104.35 ? 575 ALA M CB    1 
ATOM   4459 N N     . HIS A 1 571 ? 153.662 200.734 153.620 1.00 99.44  ? 576 HIS M N     1 
ATOM   4460 C CA    . HIS A 1 571 ? 154.958 200.130 153.879 1.00 99.44  ? 576 HIS M CA    1 
ATOM   4461 C C     . HIS A 1 571 ? 154.913 198.621 154.005 1.00 99.44  ? 576 HIS M C     1 
ATOM   4462 O O     . HIS A 1 571 ? 155.884 197.959 153.646 1.00 99.44  ? 576 HIS M O     1 
ATOM   4463 C CB    . HIS A 1 571 ? 155.570 200.734 155.140 1.00 99.44  ? 576 HIS M CB    1 
ATOM   4464 C CG    . HIS A 1 571 ? 156.034 202.142 154.951 1.00 99.44  ? 576 HIS M CG    1 
ATOM   4465 N ND1   . HIS A 1 571 ? 155.431 203.215 155.567 1.00 99.44  ? 576 HIS M ND1   1 
ATOM   4466 C CD2   . HIS A 1 571 ? 157.035 202.653 154.199 1.00 99.44  ? 576 HIS M CD2   1 
ATOM   4467 C CE1   . HIS A 1 571 ? 156.047 204.327 155.210 1.00 99.44  ? 576 HIS M CE1   1 
ATOM   4468 N NE2   . HIS A 1 571 ? 157.024 204.014 154.380 1.00 99.44  ? 576 HIS M NE2   1 
ATOM   4469 N N     . PHE A 1 572 ? 153.812 198.063 154.487 1.00 98.78  ? 577 PHE M N     1 
ATOM   4470 C CA    . PHE A 1 572 ? 153.636 196.622 154.460 1.00 98.78  ? 577 PHE M CA    1 
ATOM   4471 C C     . PHE A 1 572 ? 152.149 196.337 154.512 1.00 98.78  ? 577 PHE M C     1 
ATOM   4472 O O     . PHE A 1 572 ? 151.342 197.227 154.787 1.00 98.78  ? 577 PHE M O     1 
ATOM   4473 C CB    . PHE A 1 572 ? 154.372 195.933 155.613 1.00 98.78  ? 577 PHE M CB    1 
ATOM   4474 C CG    . PHE A 1 572 ? 153.748 196.161 156.951 1.00 98.78  ? 577 PHE M CG    1 
ATOM   4475 C CD1   . PHE A 1 572 ? 153.954 197.339 157.628 1.00 98.78  ? 577 PHE M CD1   1 
ATOM   4476 C CD2   . PHE A 1 572 ? 152.964 195.193 157.536 1.00 98.78  ? 577 PHE M CD2   1 
ATOM   4477 C CE1   . PHE A 1 572 ? 153.383 197.546 158.851 1.00 98.78  ? 577 PHE M CE1   1 
ATOM   4478 C CE2   . PHE A 1 572 ? 152.399 195.402 158.758 1.00 98.78  ? 577 PHE M CE2   1 
ATOM   4479 C CZ    . PHE A 1 572 ? 152.606 196.580 159.415 1.00 98.78  ? 577 PHE M CZ    1 
ATOM   4480 N N     . SER A 1 573 ? 151.792 195.089 154.234 1.00 102.00 ? 578 SER M N     1 
ATOM   4481 C CA    . SER A 1 573 ? 150.397 194.684 154.221 1.00 102.00 ? 578 SER M CA    1 
ATOM   4482 C C     . SER A 1 573 ? 150.226 193.390 154.993 1.00 102.00 ? 578 SER M C     1 
ATOM   4483 O O     . SER A 1 573 ? 150.952 192.420 154.761 1.00 102.00 ? 578 SER M O     1 
ATOM   4484 C CB    . SER A 1 573 ? 149.881 194.504 152.794 1.00 102.00 ? 578 SER M CB    1 
ATOM   4485 O OG    . SER A 1 573 ? 150.530 193.425 152.151 1.00 102.00 ? 578 SER M OG    1 
ATOM   4486 N N     . LEU A 1 574 ? 149.266 193.385 155.904 1.00 105.68 ? 579 LEU M N     1 
ATOM   4487 C CA    . LEU A 1 574 ? 148.767 192.183 156.542 1.00 105.68 ? 579 LEU M CA    1 
ATOM   4488 C C     . LEU A 1 574 ? 147.465 191.779 155.873 1.00 105.68 ? 579 LEU M C     1 
ATOM   4489 O O     . LEU A 1 574 ? 146.809 192.586 155.211 1.00 105.68 ? 579 LEU M O     1 
ATOM   4490 C CB    . LEU A 1 574 ? 148.524 192.409 158.035 1.00 105.68 ? 579 LEU M CB    1 
ATOM   4491 C CG    . LEU A 1 574 ? 149.541 191.859 159.025 1.00 105.68 ? 579 LEU M CG    1 
ATOM   4492 C CD1   . LEU A 1 574 ? 150.942 192.282 158.651 1.00 105.68 ? 579 LEU M CD1   1 
ATOM   4493 C CD2   . LEU A 1 574 ? 149.199 192.351 160.403 1.00 105.68 ? 579 LEU M CD2   1 
ATOM   4494 N N     . ILE A 1 575 ? 147.091 190.520 156.049 1.00 108.99 ? 580 ILE M N     1 
ATOM   4495 C CA    . ILE A 1 575 ? 145.771 190.048 155.662 1.00 108.99 ? 580 ILE M CA    1 
ATOM   4496 C C     . ILE A 1 575 ? 145.026 189.681 156.934 1.00 108.99 ? 580 ILE M C     1 
ATOM   4497 O O     . ILE A 1 575 ? 145.598 189.078 157.849 1.00 108.99 ? 580 ILE M O     1 
ATOM   4498 C CB    . ILE A 1 575 ? 145.837 188.866 154.678 1.00 108.99 ? 580 ILE M CB    1 
ATOM   4499 C CG1   . ILE A 1 575 ? 146.059 187.537 155.394 1.00 108.99 ? 580 ILE M CG1   1 
ATOM   4500 C CG2   . ILE A 1 575 ? 146.943 189.078 153.681 1.00 108.99 ? 580 ILE M CG2   1 
ATOM   4501 C CD1   . ILE A 1 575 ? 146.003 186.344 154.470 1.00 108.99 ? 580 ILE M CD1   1 
ATOM   4502 N N     . HIS A 1 576 ? 143.777 190.098 157.015 1.00 113.78 ? 581 HIS M N     1 
ATOM   4503 C CA    . HIS A 1 576 ? 142.905 189.764 158.124 1.00 113.78 ? 581 HIS M CA    1 
ATOM   4504 C C     . HIS A 1 576 ? 141.717 188.974 157.589 1.00 113.78 ? 581 HIS M C     1 
ATOM   4505 O O     . HIS A 1 576 ? 141.669 188.607 156.414 1.00 113.78 ? 581 HIS M O     1 
ATOM   4506 C CB    . HIS A 1 576 ? 142.442 191.024 158.850 1.00 113.78 ? 581 HIS M CB    1 
ATOM   4507 C CG    . HIS A 1 576 ? 143.552 191.907 159.325 1.00 113.78 ? 581 HIS M CG    1 
ATOM   4508 N ND1   . HIS A 1 576 ? 144.213 191.691 160.515 1.00 113.78 ? 581 HIS M ND1   1 
ATOM   4509 C CD2   . HIS A 1 576 ? 144.092 193.028 158.793 1.00 113.78 ? 581 HIS M CD2   1 
ATOM   4510 C CE1   . HIS A 1 576 ? 145.124 192.632 160.686 1.00 113.78 ? 581 HIS M CE1   1 
ATOM   4511 N NE2   . HIS A 1 576 ? 145.071 193.456 159.655 1.00 113.78 ? 581 HIS M NE2   1 
ATOM   4512 N N     . TYR A 1 577 ? 140.746 188.711 158.464 1.00 124.99 ? 582 TYR M N     1 
ATOM   4513 C CA    . TYR A 1 577 ? 139.501 188.125 157.986 1.00 124.99 ? 582 TYR M CA    1 
ATOM   4514 C C     . TYR A 1 577 ? 138.751 189.098 157.086 1.00 124.99 ? 582 TYR M C     1 
ATOM   4515 O O     . TYR A 1 577 ? 138.067 188.676 156.149 1.00 124.99 ? 582 TYR M O     1 
ATOM   4516 C CB    . TYR A 1 577 ? 138.625 187.686 159.165 1.00 124.99 ? 582 TYR M CB    1 
ATOM   4517 C CG    . TYR A 1 577 ? 137.929 188.804 159.915 1.00 124.99 ? 582 TYR M CG    1 
ATOM   4518 C CD1   . TYR A 1 577 ? 138.423 189.276 161.120 1.00 124.99 ? 582 TYR M CD1   1 
ATOM   4519 C CD2   . TYR A 1 577 ? 136.764 189.375 159.421 1.00 124.99 ? 582 TYR M CD2   1 
ATOM   4520 C CE1   . TYR A 1 577 ? 137.781 190.289 161.803 1.00 124.99 ? 582 TYR M CE1   1 
ATOM   4521 C CE2   . TYR A 1 577 ? 136.124 190.390 160.088 1.00 124.99 ? 582 TYR M CE2   1 
ATOM   4522 C CZ    . TYR A 1 577 ? 136.630 190.844 161.277 1.00 124.99 ? 582 TYR M CZ    1 
ATOM   4523 O OH    . TYR A 1 577 ? 135.970 191.856 161.933 1.00 124.99 ? 582 TYR M OH    1 
ATOM   4524 N N     . ALA A 1 578 ? 138.877 190.396 157.341 1.00 123.22 ? 583 ALA M N     1 
ATOM   4525 C CA    . ALA A 1 578 ? 138.130 191.409 156.612 1.00 123.22 ? 583 ALA M CA    1 
ATOM   4526 C C     . ALA A 1 578 ? 138.870 191.933 155.389 1.00 123.22 ? 583 ALA M C     1 
ATOM   4527 O O     . ALA A 1 578 ? 138.491 192.979 154.854 1.00 123.22 ? 583 ALA M O     1 
ATOM   4528 C CB    . ALA A 1 578 ? 137.776 192.569 157.542 1.00 123.22 ? 583 ALA M CB    1 
ATOM   4529 N N     . GLY A 1 579 ? 139.908 191.245 154.941 1.00 114.90 ? 584 GLY M N     1 
ATOM   4530 C CA    . GLY A 1 579 ? 140.595 191.585 153.715 1.00 114.90 ? 584 GLY M CA    1 
ATOM   4531 C C     . GLY A 1 579 ? 142.045 191.950 153.957 1.00 114.90 ? 584 GLY M C     1 
ATOM   4532 O O     . GLY A 1 579 ? 142.538 191.963 155.083 1.00 114.90 ? 584 GLY M O     1 
ATOM   4533 N N     . ILE A 1 580 ? 142.727 192.247 152.857 1.00 108.74 ? 585 ILE M N     1 
ATOM   4534 C CA    . ILE A 1 580 ? 144.114 192.693 152.899 1.00 108.74 ? 585 ILE M CA    1 
ATOM   4535 C C     . ILE A 1 580 ? 144.137 194.161 153.299 1.00 108.74 ? 585 ILE M C     1 
ATOM   4536 O O     . ILE A 1 580 ? 143.490 194.998 152.662 1.00 108.74 ? 585 ILE M O     1 
ATOM   4537 C CB    . ILE A 1 580 ? 144.800 192.487 151.544 1.00 108.74 ? 585 ILE M CB    1 
ATOM   4538 C CG1   . ILE A 1 580 ? 145.026 191.001 151.279 1.00 108.74 ? 585 ILE M CG1   1 
ATOM   4539 C CG2   . ILE A 1 580 ? 146.100 193.250 151.498 1.00 108.74 ? 585 ILE M CG2   1 
ATOM   4540 C CD1   . ILE A 1 580 ? 145.939 190.730 150.111 1.00 108.74 ? 585 ILE M CD1   1 
ATOM   4541 N N     . VAL A 1 581 ? 144.888 194.480 154.347 1.00 106.78 ? 586 VAL M N     1 
ATOM   4542 C CA    . VAL A 1 581 ? 145.006 195.846 154.839 1.00 106.78 ? 586 VAL M CA    1 
ATOM   4543 C C     . VAL A 1 581 ? 146.454 196.281 154.712 1.00 106.78 ? 586 VAL M C     1 
ATOM   4544 O O     . VAL A 1 581 ? 147.364 195.549 155.115 1.00 106.78 ? 586 VAL M O     1 
ATOM   4545 C CB    . VAL A 1 581 ? 144.529 195.972 156.293 1.00 106.78 ? 586 VAL M CB    1 
ATOM   4546 C CG1   . VAL A 1 581 ? 144.410 197.431 156.672 1.00 106.78 ? 586 VAL M CG1   1 
ATOM   4547 C CG2   . VAL A 1 581 ? 143.210 195.264 156.467 1.00 106.78 ? 586 VAL M CG2   1 
ATOM   4548 N N     . ASP A 1 582 ? 146.667 197.460 154.146 1.00 107.85 ? 587 ASP M N     1 
ATOM   4549 C CA    . ASP A 1 582 ? 147.997 198.035 154.024 1.00 107.85 ? 587 ASP M CA    1 
ATOM   4550 C C     . ASP A 1 582 ? 148.184 199.088 155.102 1.00 107.85 ? 587 ASP M C     1 
ATOM   4551 O O     . ASP A 1 582 ? 147.381 200.020 155.210 1.00 107.85 ? 587 ASP M O     1 
ATOM   4552 C CB    . ASP A 1 582 ? 148.199 198.650 152.643 1.00 107.85 ? 587 ASP M CB    1 
ATOM   4553 C CG    . ASP A 1 582 ? 147.656 197.778 151.545 1.00 107.85 ? 587 ASP M CG    1 
ATOM   4554 O OD1   . ASP A 1 582 ? 147.616 196.549 151.742 1.00 107.85 ? 587 ASP M OD1   1 
ATOM   4555 O OD2   . ASP A 1 582 ? 147.279 198.315 150.484 1.00 107.85 ? 587 ASP M OD2   1 
ATOM   4556 N N     . TYR A 1 583 ? 149.250 198.947 155.883 1.00 102.84 ? 588 TYR M N     1 
ATOM   4557 C CA    . TYR A 1 583 ? 149.508 199.809 157.021 1.00 102.84 ? 588 TYR M CA    1 
ATOM   4558 C C     . TYR A 1 583 ? 150.709 200.695 156.743 1.00 102.84 ? 588 TYR M C     1 
ATOM   4559 O O     . TYR A 1 583 ? 151.597 200.340 155.966 1.00 102.84 ? 588 TYR M O     1 
ATOM   4560 C CB    . TYR A 1 583 ? 149.762 198.997 158.276 1.00 102.84 ? 588 TYR M CB    1 
ATOM   4561 C CG    . TYR A 1 583 ? 148.579 198.200 158.754 1.00 102.84 ? 588 TYR M CG    1 
ATOM   4562 C CD1   . TYR A 1 583 ? 148.500 196.840 158.527 1.00 102.84 ? 588 TYR M CD1   1 
ATOM   4563 C CD2   . TYR A 1 583 ? 147.549 198.808 159.453 1.00 102.84 ? 588 TYR M CD2   1 
ATOM   4564 C CE1   . TYR A 1 583 ? 147.428 196.109 158.976 1.00 102.84 ? 588 TYR M CE1   1 
ATOM   4565 C CE2   . TYR A 1 583 ? 146.473 198.083 159.902 1.00 102.84 ? 588 TYR M CE2   1 
ATOM   4566 C CZ    . TYR A 1 583 ? 146.418 196.737 159.660 1.00 102.84 ? 588 TYR M CZ    1 
ATOM   4567 O OH    . TYR A 1 583 ? 145.346 196.010 160.105 1.00 102.84 ? 588 TYR M OH    1 
ATOM   4568 N N     . ASN A 1 584 ? 150.731 201.852 157.390 1.00 99.25  ? 589 ASN M N     1 
ATOM   4569 C CA    . ASN A 1 584 ? 151.812 202.811 157.238 1.00 99.25  ? 589 ASN M CA    1 
ATOM   4570 C C     . ASN A 1 584 ? 152.646 202.871 158.511 1.00 99.25  ? 589 ASN M C     1 
ATOM   4571 O O     . ASN A 1 584 ? 152.108 202.816 159.620 1.00 99.25  ? 589 ASN M O     1 
ATOM   4572 C CB    . ASN A 1 584 ? 151.273 204.195 156.909 1.00 99.25  ? 589 ASN M CB    1 
ATOM   4573 C CG    . ASN A 1 584 ? 152.289 205.043 156.211 1.00 99.25  ? 589 ASN M CG    1 
ATOM   4574 O OD1   . ASN A 1 584 ? 152.861 204.634 155.207 1.00 99.25  ? 589 ASN M OD1   1 
ATOM   4575 N ND2   . ASN A 1 584 ? 152.542 206.224 156.747 1.00 99.25  ? 589 ASN M ND2   1 
ATOM   4576 N N     . ILE A 1 585 ? 153.963 203.000 158.347 1.00 93.39  ? 590 ILE M N     1 
ATOM   4577 C CA    . ILE A 1 585 ? 154.866 202.933 159.490 1.00 93.39  ? 590 ILE M CA    1 
ATOM   4578 C C     . ILE A 1 585 ? 155.057 204.297 160.132 1.00 93.39  ? 590 ILE M C     1 
ATOM   4579 O O     . ILE A 1 585 ? 155.120 204.406 161.359 1.00 93.39  ? 590 ILE M O     1 
ATOM   4580 C CB    . ILE A 1 585 ? 156.209 202.325 159.059 1.00 93.39  ? 590 ILE M CB    1 
ATOM   4581 C CG1   . ILE A 1 585 ? 156.025 200.868 158.667 1.00 93.39  ? 590 ILE M CG1   1 
ATOM   4582 C CG2   . ILE A 1 585 ? 157.218 202.430 160.167 1.00 93.39  ? 590 ILE M CG2   1 
ATOM   4583 C CD1   . ILE A 1 585 ? 155.512 200.032 159.787 1.00 93.39  ? 590 ILE M CD1   1 
ATOM   4584 N N     . ILE A 1 586 ? 155.141 205.351 159.326 1.00 91.05  ? 591 ILE M N     1 
ATOM   4585 C CA    . ILE A 1 586 ? 155.617 206.656 159.773 1.00 91.05  ? 591 ILE M CA    1 
ATOM   4586 C C     . ILE A 1 586 ? 154.933 207.119 161.053 1.00 91.05  ? 591 ILE M C     1 
ATOM   4587 O O     . ILE A 1 586 ? 153.712 207.290 161.090 1.00 91.05  ? 591 ILE M O     1 
ATOM   4588 C CB    . ILE A 1 586 ? 155.429 207.695 158.658 1.00 91.05  ? 591 ILE M CB    1 
ATOM   4589 C CG1   . ILE A 1 586 ? 156.346 207.367 157.482 1.00 91.05  ? 591 ILE M CG1   1 
ATOM   4590 C CG2   . ILE A 1 586 ? 155.696 209.087 159.183 1.00 91.05  ? 591 ILE M CG2   1 
ATOM   4591 C CD1   . ILE A 1 586 ? 157.810 207.440 157.816 1.00 91.05  ? 591 ILE M CD1   1 
ATOM   4592 N N     . GLY A 1 587 ? 155.721 207.321 162.112 1.00 91.18  ? 592 GLY M N     1 
ATOM   4593 C CA    . GLY A 1 587 ? 155.236 207.861 163.367 1.00 91.18  ? 592 GLY M CA    1 
ATOM   4594 C C     . GLY A 1 587 ? 155.018 206.854 164.477 1.00 91.18  ? 592 GLY M C     1 
ATOM   4595 O O     . GLY A 1 587 ? 154.760 207.264 165.616 1.00 91.18  ? 592 GLY M O     1 
ATOM   4596 N N     . TRP A 1 588 ? 155.115 205.556 164.188 1.00 91.99  ? 593 TRP M N     1 
ATOM   4597 C CA    . TRP A 1 588 ? 154.759 204.551 165.183 1.00 91.99  ? 593 TRP M CA    1 
ATOM   4598 C C     . TRP A 1 588 ? 155.696 204.580 166.384 1.00 91.99  ? 593 TRP M C     1 
ATOM   4599 O O     . TRP A 1 588 ? 155.243 204.502 167.531 1.00 91.99  ? 593 TRP M O     1 
ATOM   4600 C CB    . TRP A 1 588 ? 154.756 203.165 164.550 1.00 91.99  ? 593 TRP M CB    1 
ATOM   4601 C CG    . TRP A 1 588 ? 153.613 202.931 163.644 1.00 91.99  ? 593 TRP M CG    1 
ATOM   4602 C CD1   . TRP A 1 588 ? 152.855 203.871 163.016 1.00 91.99  ? 593 TRP M CD1   1 
ATOM   4603 C CD2   . TRP A 1 588 ? 153.068 201.667 163.276 1.00 91.99  ? 593 TRP M CD2   1 
ATOM   4604 N NE1   . TRP A 1 588 ? 151.882 203.268 162.266 1.00 91.99  ? 593 TRP M NE1   1 
ATOM   4605 C CE2   . TRP A 1 588 ? 151.990 201.912 162.414 1.00 91.99  ? 593 TRP M CE2   1 
ATOM   4606 C CE3   . TRP A 1 588 ? 153.390 200.349 163.591 1.00 91.99  ? 593 TRP M CE3   1 
ATOM   4607 C CZ2   . TRP A 1 588 ? 151.236 200.890 161.860 1.00 91.99  ? 593 TRP M CZ2   1 
ATOM   4608 C CZ3   . TRP A 1 588 ? 152.639 199.339 163.045 1.00 91.99  ? 593 TRP M CZ3   1 
ATOM   4609 C CH2   . TRP A 1 588 ? 151.576 199.613 162.187 1.00 91.99  ? 593 TRP M CH2   1 
ATOM   4610 N N     . LEU A 1 589 ? 157.006 204.651 166.143 1.00 87.44  ? 594 LEU M N     1 
ATOM   4611 C CA    . LEU A 1 589 ? 157.959 204.729 167.245 1.00 87.44  ? 594 LEU M CA    1 
ATOM   4612 C C     . LEU A 1 589 ? 157.640 205.896 168.163 1.00 87.44  ? 594 LEU M C     1 
ATOM   4613 O O     . LEU A 1 589 ? 157.524 205.730 169.381 1.00 87.44  ? 594 LEU M O     1 
ATOM   4614 C CB    . LEU A 1 589 ? 159.381 204.854 166.705 1.00 87.44  ? 594 LEU M CB    1 
ATOM   4615 C CG    . LEU A 1 589 ? 160.159 203.572 166.433 1.00 87.44  ? 594 LEU M CG    1 
ATOM   4616 C CD1   . LEU A 1 589 ? 159.549 202.770 165.324 1.00 87.44  ? 594 LEU M CD1   1 
ATOM   4617 C CD2   . LEU A 1 589 ? 161.571 203.948 166.076 1.00 87.44  ? 594 LEU M CD2   1 
ATOM   4618 N N     . GLN A 1 590 ? 157.485 207.086 167.593 1.00 90.68  ? 595 GLN M N     1 
ATOM   4619 C CA    . GLN A 1 590 ? 157.239 208.262 168.410 1.00 90.68  ? 595 GLN M CA    1 
ATOM   4620 C C     . GLN A 1 590 ? 155.907 208.179 169.137 1.00 90.68  ? 595 GLN M C     1 
ATOM   4621 O O     . GLN A 1 590 ? 155.785 208.677 170.259 1.00 90.68  ? 595 GLN M O     1 
ATOM   4622 C CB    . GLN A 1 590 ? 157.290 209.508 167.537 1.00 90.68  ? 595 GLN M CB    1 
ATOM   4623 C CG    . GLN A 1 590 ? 156.746 210.752 168.183 1.00 90.68  ? 595 GLN M CG    1 
ATOM   4624 C CD    . GLN A 1 590 ? 156.705 211.910 167.218 1.00 90.68  ? 595 GLN M CD    1 
ATOM   4625 O OE1   . GLN A 1 590 ? 157.743 212.416 166.797 1.00 90.68  ? 595 GLN M OE1   1 
ATOM   4626 N NE2   . GLN A 1 590 ? 155.502 212.333 166.852 1.00 90.68  ? 595 GLN M NE2   1 
ATOM   4627 N N     . LYS A 1 591 ? 154.907 207.541 168.542 1.00 91.97  ? 596 LYS M N     1 
ATOM   4628 C CA    . LYS A 1 591 ? 153.595 207.546 169.169 1.00 91.97  ? 596 LYS M CA    1 
ATOM   4629 C C     . LYS A 1 591 ? 153.373 206.388 170.126 1.00 91.97  ? 596 LYS M C     1 
ATOM   4630 O O     . LYS A 1 591 ? 152.398 206.414 170.881 1.00 91.97  ? 596 LYS M O     1 
ATOM   4631 C CB    . LYS A 1 591 ? 152.498 207.538 168.106 1.00 91.97  ? 596 LYS M CB    1 
ATOM   4632 C CG    . LYS A 1 591 ? 152.087 206.168 167.629 1.00 91.97  ? 596 LYS M CG    1 
ATOM   4633 C CD    . LYS A 1 591 ? 150.775 206.253 166.871 1.00 91.97  ? 596 LYS M CD    1 
ATOM   4634 C CE    . LYS A 1 591 ? 150.790 207.396 165.867 1.00 91.97  ? 596 LYS M CE    1 
ATOM   4635 N NZ    . LYS A 1 591 ? 149.494 207.505 165.149 1.00 91.97  ? 596 LYS M NZ    1 
ATOM   4636 N N     . ASN A 1 592 ? 154.235 205.375 170.114 1.00 87.39  ? 597 ASN M N     1 
ATOM   4637 C CA    . ASN A 1 592 ? 154.044 204.239 171.005 1.00 87.39  ? 597 ASN M CA    1 
ATOM   4638 C C     . ASN A 1 592 ? 154.674 204.440 172.376 1.00 87.39  ? 597 ASN M C     1 
ATOM   4639 O O     . ASN A 1 592 ? 154.338 203.708 173.309 1.00 87.39  ? 597 ASN M O     1 
ATOM   4640 C CB    . ASN A 1 592 ? 154.607 202.978 170.361 1.00 87.39  ? 597 ASN M CB    1 
ATOM   4641 C CG    . ASN A 1 592 ? 154.239 201.733 171.115 1.00 87.39  ? 597 ASN M CG    1 
ATOM   4642 O OD1   . ASN A 1 592 ? 153.230 201.694 171.810 1.00 87.39  ? 597 ASN M OD1   1 
ATOM   4643 N ND2   . ASN A 1 592 ? 155.055 200.701 170.985 1.00 87.39  ? 597 ASN M ND2   1 
ATOM   4644 N N     . LYS A 1 593 ? 155.573 205.407 172.524 1.00 84.20  ? 598 LYS M N     1 
ATOM   4645 C CA    . LYS A 1 593 ? 156.267 205.598 173.789 1.00 84.20  ? 598 LYS M CA    1 
ATOM   4646 C C     . LYS A 1 593 ? 155.316 206.111 174.861 1.00 84.20  ? 598 LYS M C     1 
ATOM   4647 O O     . LYS A 1 593 ? 154.526 207.025 174.620 1.00 84.20  ? 598 LYS M O     1 
ATOM   4648 C CB    . LYS A 1 593 ? 157.425 206.571 173.609 1.00 84.20  ? 598 LYS M CB    1 
ATOM   4649 C CG    . LYS A 1 593 ? 158.575 205.997 172.826 1.00 84.20  ? 598 LYS M CG    1 
ATOM   4650 C CD    . LYS A 1 593 ? 159.631 207.039 172.583 1.00 84.20  ? 598 LYS M CD    1 
ATOM   4651 C CE    . LYS A 1 593 ? 160.713 206.502 171.684 1.00 84.20  ? 598 LYS M CE    1 
ATOM   4652 N NZ    . LYS A 1 593 ? 161.454 205.404 172.347 1.00 84.20  ? 598 LYS M NZ    1 
ATOM   4653 N N     . ASP A 1 594 ? 155.410 205.532 176.057 1.00 84.31  ? 599 ASP M N     1 
ATOM   4654 C CA    . ASP A 1 594 ? 154.569 205.921 177.190 1.00 84.31  ? 599 ASP M CA    1 
ATOM   4655 C C     . ASP A 1 594 ? 155.405 205.964 178.467 1.00 84.31  ? 599 ASP M C     1 
ATOM   4656 O O     . ASP A 1 594 ? 155.125 205.258 179.435 1.00 84.31  ? 599 ASP M O     1 
ATOM   4657 C CB    . ASP A 1 594 ? 153.393 204.951 177.320 1.00 84.31  ? 599 ASP M CB    1 
ATOM   4658 C CG    . ASP A 1 594 ? 152.367 205.391 178.349 1.00 84.31  ? 599 ASP M CG    1 
ATOM   4659 O OD1   . ASP A 1 594 ? 151.386 206.058 177.962 1.00 84.31  ? 599 ASP M OD1   1 
ATOM   4660 O OD2   . ASP A 1 594 ? 152.513 205.040 179.538 1.00 84.31  ? 599 ASP M OD2   1 
ATOM   4661 N N     . PRO A 1 595 ? 156.449 206.797 178.508 1.00 81.37  ? 600 PRO M N     1 
ATOM   4662 C CA    . PRO A 1 595 ? 157.261 206.892 179.727 1.00 81.37  ? 600 PRO M CA    1 
ATOM   4663 C C     . PRO A 1 595 ? 156.604 207.787 180.764 1.00 81.37  ? 600 PRO M C     1 
ATOM   4664 O O     . PRO A 1 595 ? 156.618 209.015 180.646 1.00 81.37  ? 600 PRO M O     1 
ATOM   4665 C CB    . PRO A 1 595 ? 158.580 207.481 179.213 1.00 81.37  ? 600 PRO M CB    1 
ATOM   4666 C CG    . PRO A 1 595 ? 158.189 208.302 178.077 1.00 81.37  ? 600 PRO M CG    1 
ATOM   4667 C CD    . PRO A 1 595 ? 156.956 207.699 177.462 1.00 81.37  ? 600 PRO M CD    1 
ATOM   4668 N N     . LEU A 1 596 ? 156.051 207.174 181.803 1.00 83.08  ? 601 LEU M N     1 
ATOM   4669 C CA    . LEU A 1 596 ? 155.409 207.930 182.869 1.00 83.08  ? 601 LEU M CA    1 
ATOM   4670 C C     . LEU A 1 596 ? 156.441 208.427 183.874 1.00 83.08  ? 601 LEU M C     1 
ATOM   4671 O O     . LEU A 1 596 ? 157.348 207.697 184.270 1.00 83.08  ? 601 LEU M O     1 
ATOM   4672 C CB    . LEU A 1 596 ? 154.369 207.065 183.575 1.00 83.08  ? 601 LEU M CB    1 
ATOM   4673 C CG    . LEU A 1 596 ? 153.289 207.798 184.356 1.00 83.08  ? 601 LEU M CG    1 
ATOM   4674 C CD1   . LEU A 1 596 ? 152.666 208.850 183.483 1.00 83.08  ? 601 LEU M CD1   1 
ATOM   4675 C CD2   . LEU A 1 596 ? 152.240 206.827 184.831 1.00 83.08  ? 601 LEU M CD2   1 
ATOM   4676 N N     . ASN A 1 597 ? 156.281 209.674 184.305 1.00 83.93  ? 602 ASN M N     1 
ATOM   4677 C CA    . ASN A 1 597 ? 157.261 210.343 185.154 1.00 83.93  ? 602 ASN M CA    1 
ATOM   4678 C C     . ASN A 1 597 ? 156.844 210.204 186.614 1.00 83.93  ? 602 ASN M C     1 
ATOM   4679 O O     . ASN A 1 597 ? 155.866 210.818 187.054 1.00 83.93  ? 602 ASN M O     1 
ATOM   4680 C CB    . ASN A 1 597 ? 157.403 211.808 184.758 1.00 83.93  ? 602 ASN M CB    1 
ATOM   4681 C CG    . ASN A 1 597 ? 158.580 212.474 185.419 1.00 83.93  ? 602 ASN M CG    1 
ATOM   4682 O OD1   . ASN A 1 597 ? 158.776 212.355 186.623 1.00 83.93  ? 602 ASN M OD1   1 
ATOM   4683 N ND2   . ASN A 1 597 ? 159.376 213.183 184.633 1.00 83.93  ? 602 ASN M ND2   1 
ATOM   4684 N N     . GLU A 1 598 ? 157.624 209.431 187.369 1.00 88.36  ? 603 GLU M N     1 
ATOM   4685 C CA    . GLU A 1 598 ? 157.233 209.036 188.717 1.00 88.36  ? 603 GLU M CA    1 
ATOM   4686 C C     . GLU A 1 598 ? 157.280 210.205 189.690 1.00 88.36  ? 603 GLU M C     1 
ATOM   4687 O O     . GLU A 1 598 ? 156.462 210.282 190.611 1.00 88.36  ? 603 GLU M O     1 
ATOM   4688 C CB    . GLU A 1 598 ? 158.143 207.917 189.199 1.00 88.36  ? 603 GLU M CB    1 
ATOM   4689 C CG    . GLU A 1 598 ? 157.589 207.123 190.340 1.00 88.36  ? 603 GLU M CG    1 
ATOM   4690 C CD    . GLU A 1 598 ? 156.646 206.044 189.879 1.00 88.36  ? 603 GLU M CD    1 
ATOM   4691 O OE1   . GLU A 1 598 ? 156.679 205.705 188.679 1.00 88.36  ? 603 GLU M OE1   1 
ATOM   4692 O OE2   . GLU A 1 598 ? 155.881 205.536 190.723 1.00 88.36  ? 603 GLU M OE2   1 
ATOM   4693 N N     . THR A 1 599 ? 158.234 211.118 189.521 1.00 85.72  ? 604 THR M N     1 
ATOM   4694 C CA    . THR A 1 599 ? 158.296 212.259 190.424 1.00 85.72  ? 604 THR M CA    1 
ATOM   4695 C C     . THR A 1 599 ? 157.078 213.149 190.256 1.00 85.72  ? 604 THR M C     1 
ATOM   4696 O O     . THR A 1 599 ? 156.472 213.578 191.242 1.00 85.72  ? 604 THR M O     1 
ATOM   4697 C CB    . THR A 1 599 ? 159.565 213.066 190.189 1.00 85.72  ? 604 THR M CB    1 
ATOM   4698 O OG1   . THR A 1 599 ? 159.422 213.821 188.984 1.00 85.72  ? 604 THR M OG1   1 
ATOM   4699 C CG2   . THR A 1 599 ? 160.741 212.153 190.061 1.00 85.72  ? 604 THR M CG2   1 
ATOM   4700 N N     . VAL A 1 600 ? 156.683 213.417 189.012 1.00 88.25  ? 605 VAL M N     1 
ATOM   4701 C CA    . VAL A 1 600 ? 155.501 214.236 188.793 1.00 88.25  ? 605 VAL M CA    1 
ATOM   4702 C C     . VAL A 1 600 ? 154.249 213.494 189.229 1.00 88.25  ? 605 VAL M C     1 
ATOM   4703 O O     . VAL A 1 600 ? 153.282 214.113 189.681 1.00 88.25  ? 605 VAL M O     1 
ATOM   4704 C CB    . VAL A 1 600 ? 155.419 214.673 187.324 1.00 88.25  ? 605 VAL M CB    1 
ATOM   4705 C CG1   . VAL A 1 600 ? 154.474 215.834 187.183 1.00 88.25  ? 605 VAL M CG1   1 
ATOM   4706 C CG2   . VAL A 1 600 ? 156.783 215.056 186.823 1.00 88.25  ? 605 VAL M CG2   1 
ATOM   4707 N N     . VAL A 1 601 ? 154.236 212.168 189.122 1.00 90.07  ? 606 VAL M N     1 
ATOM   4708 C CA    . VAL A 1 601 ? 153.094 211.424 189.644 1.00 90.07  ? 606 VAL M CA    1 
ATOM   4709 C C     . VAL A 1 601 ? 153.002 211.583 191.156 1.00 90.07  ? 606 VAL M C     1 
ATOM   4710 O O     . VAL A 1 601 ? 151.909 211.714 191.719 1.00 90.07  ? 606 VAL M O     1 
ATOM   4711 C CB    . VAL A 1 601 ? 153.179 209.948 189.224 1.00 90.07  ? 606 VAL M CB    1 
ATOM   4712 C CG1   . VAL A 1 601 ? 152.349 209.079 190.139 1.00 90.07  ? 606 VAL M CG1   1 
ATOM   4713 C CG2   . VAL A 1 601 ? 152.712 209.796 187.801 1.00 90.07  ? 606 VAL M CG2   1 
ATOM   4714 N N     . GLY A 1 602 ? 154.143 211.574 191.842 1.00 91.62  ? 607 GLY M N     1 
ATOM   4715 C CA    . GLY A 1 602 ? 154.125 211.850 193.269 1.00 91.62  ? 607 GLY M CA    1 
ATOM   4716 C C     . GLY A 1 602 ? 153.642 213.253 193.576 1.00 91.62  ? 607 GLY M C     1 
ATOM   4717 O O     . GLY A 1 602 ? 152.883 213.468 194.527 1.00 91.62  ? 607 GLY M O     1 
ATOM   4718 N N     . LEU A 1 603 ? 154.070 214.227 192.770 1.00 92.02  ? 608 LEU M N     1 
ATOM   4719 C CA    . LEU A 1 603 ? 153.532 215.579 192.888 1.00 92.02  ? 608 LEU M CA    1 
ATOM   4720 C C     . LEU A 1 603 ? 152.016 215.583 192.789 1.00 92.02  ? 608 LEU M C     1 
ATOM   4721 O O     . LEU A 1 603 ? 151.341 216.256 193.573 1.00 92.02  ? 608 LEU M O     1 
ATOM   4722 C CB    . LEU A 1 603 ? 154.133 216.485 191.819 1.00 92.02  ? 608 LEU M CB    1 
ATOM   4723 C CG    . LEU A 1 603 ? 155.355 217.309 192.204 1.00 92.02  ? 608 LEU M CG    1 
ATOM   4724 C CD1   . LEU A 1 603 ? 156.506 216.424 192.575 1.00 92.02  ? 608 LEU M CD1   1 
ATOM   4725 C CD2   . LEU A 1 603 ? 155.730 218.194 191.037 1.00 92.02  ? 608 LEU M CD2   1 
ATOM   4726 N N     . TYR A 1 604 ? 151.464 214.836 191.834 1.00 94.92  ? 609 TYR M N     1 
ATOM   4727 C CA    . TYR A 1 604 ? 150.011 214.762 191.716 1.00 94.92  ? 609 TYR M CA    1 
ATOM   4728 C C     . TYR A 1 604 ? 149.400 214.133 192.957 1.00 94.92  ? 609 TYR M C     1 
ATOM   4729 O O     . TYR A 1 604 ? 148.358 214.586 193.442 1.00 94.92  ? 609 TYR M O     1 
ATOM   4730 C CB    . TYR A 1 604 ? 149.601 213.974 190.473 1.00 94.92  ? 609 TYR M CB    1 
ATOM   4731 C CG    . TYR A 1 604 ? 149.986 214.621 189.164 1.00 94.92  ? 609 TYR M CG    1 
ATOM   4732 C CD1   . TYR A 1 604 ? 150.548 215.884 189.131 1.00 94.92  ? 609 TYR M CD1   1 
ATOM   4733 C CD2   . TYR A 1 604 ? 149.776 213.969 187.961 1.00 94.92  ? 609 TYR M CD2   1 
ATOM   4734 C CE1   . TYR A 1 604 ? 150.904 216.470 187.947 1.00 94.92  ? 609 TYR M CE1   1 
ATOM   4735 C CE2   . TYR A 1 604 ? 150.126 214.551 186.772 1.00 94.92  ? 609 TYR M CE2   1 
ATOM   4736 C CZ    . TYR A 1 604 ? 150.691 215.802 186.771 1.00 94.92  ? 609 TYR M CZ    1 
ATOM   4737 O OH    . TYR A 1 604 ? 151.045 216.393 185.585 1.00 94.92  ? 609 TYR M OH    1 
ATOM   4738 N N     . GLN A 1 605 ? 150.031 213.084 193.484 1.00 96.15  ? 610 GLN M N     1 
ATOM   4739 C CA    . GLN A 1 605 ? 149.549 212.493 194.728 1.00 96.15  ? 610 GLN M CA    1 
ATOM   4740 C C     . GLN A 1 605 ? 149.530 213.514 195.855 1.00 96.15  ? 610 GLN M C     1 
ATOM   4741 O O     . GLN A 1 605 ? 148.728 213.395 196.786 1.00 96.15  ? 610 GLN M O     1 
ATOM   4742 C CB    . GLN A 1 605 ? 150.414 211.298 195.132 1.00 96.15  ? 610 GLN M CB    1 
ATOM   4743 C CG    . GLN A 1 605 ? 150.433 210.164 194.133 1.00 96.15  ? 610 GLN M CG    1 
ATOM   4744 C CD    . GLN A 1 605 ? 151.088 208.908 194.672 1.00 96.15  ? 610 GLN M CD    1 
ATOM   4745 O OE1   . GLN A 1 605 ? 152.222 208.588 194.326 1.00 96.15  ? 610 GLN M OE1   1 
ATOM   4746 N NE2   . GLN A 1 605 ? 150.370 208.183 195.515 1.00 96.15  ? 610 GLN M NE2   1 
ATOM   4747 N N     . LYS A 1 606 ? 150.413 214.509 195.799 1.00 97.19  ? 611 LYS M N     1 
ATOM   4748 C CA    . LYS A 1 606 ? 150.491 215.544 196.821 1.00 97.19  ? 611 LYS M CA    1 
ATOM   4749 C C     . LYS A 1 606 ? 149.796 216.835 196.405 1.00 97.19  ? 611 LYS M C     1 
ATOM   4750 O O     . LYS A 1 606 ? 150.188 217.919 196.851 1.00 97.19  ? 611 LYS M O     1 
ATOM   4751 C CB    . LYS A 1 606 ? 151.949 215.830 197.173 1.00 97.19  ? 611 LYS M CB    1 
ATOM   4752 C CG    . LYS A 1 606 ? 152.524 214.934 198.253 1.00 97.19  ? 611 LYS M CG    1 
ATOM   4753 C CD    . LYS A 1 606 ? 153.868 215.452 198.703 1.00 97.19  ? 611 LYS M CD    1 
ATOM   4754 C CE    . LYS A 1 606 ? 153.785 216.933 199.050 1.00 97.19  ? 611 LYS M CE    1 
ATOM   4755 N NZ    . LYS A 1 606 ? 155.067 217.657 198.812 1.00 97.19  ? 611 LYS M NZ    1 
ATOM   4756 N N     . SER A 1 607 ? 148.777 216.749 195.554 1.00 99.95  ? 612 SER M N     1 
ATOM   4757 C CA    . SER A 1 607 ? 148.112 217.941 195.054 1.00 99.95  ? 612 SER M CA    1 
ATOM   4758 C C     . SER A 1 607 ? 147.156 218.509 196.097 1.00 99.95  ? 612 SER M C     1 
ATOM   4759 O O     . SER A 1 607 ? 146.979 217.961 197.188 1.00 99.95  ? 612 SER M O     1 
ATOM   4760 C CB    . SER A 1 607 ? 147.356 217.637 193.765 1.00 99.95  ? 612 SER M CB    1 
ATOM   4761 O OG    . SER A 1 607 ? 146.557 218.744 193.387 1.00 99.95  ? 612 SER M OG    1 
ATOM   4762 N N     . SER A 1 608 ? 146.522 219.626 195.743 1.00 101.77 ? 613 SER M N     1 
ATOM   4763 C CA    . SER A 1 608 ? 145.506 220.269 196.566 1.00 101.77 ? 613 SER M CA    1 
ATOM   4764 C C     . SER A 1 608 ? 144.140 220.235 195.887 1.00 101.77 ? 613 SER M C     1 
ATOM   4765 O O     . SER A 1 608 ? 143.369 221.192 195.976 1.00 101.77 ? 613 SER M O     1 
ATOM   4766 C CB    . SER A 1 608 ? 145.908 221.706 196.882 1.00 101.77 ? 613 SER M CB    1 
ATOM   4767 O OG    . SER A 1 608 ? 146.026 222.472 195.696 1.00 101.77 ? 613 SER M OG    1 
ATOM   4768 N N     . LEU A 1 609 ? 143.839 219.139 195.193 1.00 102.80 ? 614 LEU M N     1 
ATOM   4769 C CA    . LEU A 1 609 ? 142.653 219.041 194.354 1.00 102.80 ? 614 LEU M CA    1 
ATOM   4770 C C     . LEU A 1 609 ? 142.000 217.673 194.488 1.00 102.80 ? 614 LEU M C     1 
ATOM   4771 O O     . LEU A 1 609 ? 142.266 216.938 195.442 1.00 102.80 ? 614 LEU M O     1 
ATOM   4772 C CB    . LEU A 1 609 ? 143.019 219.307 192.896 1.00 102.80 ? 614 LEU M CB    1 
ATOM   4773 C CG    . LEU A 1 609 ? 142.014 220.033 192.008 1.00 102.80 ? 614 LEU M CG    1 
ATOM   4774 C CD1   . LEU A 1 609 ? 141.774 221.437 192.527 1.00 102.80 ? 614 LEU M CD1   1 
ATOM   4775 C CD2   . LEU A 1 609 ? 142.521 220.063 190.579 1.00 102.80 ? 614 LEU M CD2   1 
ATOM   4776 N N     . LYS A 1 610 ? 141.106 217.347 193.558 1.00 105.93 ? 615 LYS M N     1 
ATOM   4777 C CA    . LYS A 1 610 ? 140.651 215.974 193.391 1.00 105.93 ? 615 LYS M CA    1 
ATOM   4778 C C     . LYS A 1 610 ? 141.676 215.121 192.657 1.00 105.93 ? 615 LYS M C     1 
ATOM   4779 O O     . LYS A 1 610 ? 141.586 213.890 192.699 1.00 105.93 ? 615 LYS M O     1 
ATOM   4780 C CB    . LYS A 1 610 ? 139.319 215.975 192.644 1.00 105.93 ? 615 LYS M CB    1 
ATOM   4781 C CG    . LYS A 1 610 ? 138.717 214.614 192.348 1.00 105.93 ? 615 LYS M CG    1 
ATOM   4782 C CD    . LYS A 1 610 ? 139.036 214.189 190.938 1.00 105.93 ? 615 LYS M CD    1 
ATOM   4783 C CE    . LYS A 1 610 ? 138.378 215.122 189.957 1.00 105.93 ? 615 LYS M CE    1 
ATOM   4784 N NZ    . LYS A 1 610 ? 138.641 214.708 188.563 1.00 105.93 ? 615 LYS M NZ    1 
ATOM   4785 N N     . LEU A 1 611 ? 142.651 215.755 191.999 1.00 101.31 ? 616 LEU M N     1 
ATOM   4786 C CA    . LEU A 1 611 ? 143.675 215.038 191.246 1.00 101.31 ? 616 LEU M CA    1 
ATOM   4787 C C     . LEU A 1 611 ? 144.357 213.966 192.081 1.00 101.31 ? 616 LEU M C     1 
ATOM   4788 O O     . LEU A 1 611 ? 144.728 212.907 191.558 1.00 101.31 ? 616 LEU M O     1 
ATOM   4789 C CB    . LEU A 1 611 ? 144.707 216.038 190.730 1.00 101.31 ? 616 LEU M CB    1 
ATOM   4790 C CG    . LEU A 1 611 ? 145.845 215.527 189.860 1.00 101.31 ? 616 LEU M CG    1 
ATOM   4791 C CD1   . LEU A 1 611 ? 145.303 214.633 188.783 1.00 101.31 ? 616 LEU M CD1   1 
ATOM   4792 C CD2   . LEU A 1 611 ? 146.587 216.693 189.249 1.00 101.31 ? 616 LEU M CD2   1 
ATOM   4793 N N     . LEU A 1 612 ? 144.524 214.219 193.377 1.00 100.59 ? 617 LEU M N     1 
ATOM   4794 C CA    . LEU A 1 612 ? 145.182 213.258 194.247 1.00 100.59 ? 617 LEU M CA    1 
ATOM   4795 C C     . LEU A 1 612 ? 144.396 211.966 194.380 1.00 100.59 ? 617 LEU M C     1 
ATOM   4796 O O     . LEU A 1 612 ? 144.966 210.945 194.774 1.00 100.59 ? 617 LEU M O     1 
ATOM   4797 C CB    . LEU A 1 612 ? 145.428 213.896 195.611 1.00 100.59 ? 617 LEU M CB    1 
ATOM   4798 C CG    . LEU A 1 612 ? 144.228 214.494 196.340 1.00 100.59 ? 617 LEU M CG    1 
ATOM   4799 C CD1   . LEU A 1 612 ? 143.492 213.472 197.199 1.00 100.59 ? 617 LEU M CD1   1 
ATOM   4800 C CD2   . LEU A 1 612 ? 144.677 215.679 197.176 1.00 100.59 ? 617 LEU M CD2   1 
ATOM   4801 N N     . SER A 1 613 ? 143.105 211.981 194.074 1.00 101.91 ? 618 SER M N     1 
ATOM   4802 C CA    . SER A 1 613 ? 142.362 210.731 194.055 1.00 101.91 ? 618 SER M CA    1 
ATOM   4803 C C     . SER A 1 613 ? 142.607 209.965 192.764 1.00 101.91 ? 618 SER M C     1 
ATOM   4804 O O     . SER A 1 613 ? 142.803 208.746 192.791 1.00 101.91 ? 618 SER M O     1 
ATOM   4805 C CB    . SER A 1 613 ? 140.872 210.996 194.240 1.00 101.91 ? 618 SER M CB    1 
ATOM   4806 O OG    . SER A 1 613 ? 140.104 209.921 193.731 1.00 101.91 ? 618 SER M OG    1 
ATOM   4807 N N     . THR A 1 614 ? 142.596 210.659 191.626 1.00 102.99 ? 619 THR M N     1 
ATOM   4808 C CA    . THR A 1 614 ? 142.826 209.981 190.357 1.00 102.99 ? 619 THR M CA    1 
ATOM   4809 C C     . THR A 1 614 ? 144.210 209.356 190.318 1.00 102.99 ? 619 THR M C     1 
ATOM   4810 O O     . THR A 1 614 ? 144.372 208.210 189.884 1.00 102.99 ? 619 THR M O     1 
ATOM   4811 C CB    . THR A 1 614 ? 142.645 210.955 189.194 1.00 102.99 ? 619 THR M CB    1 
ATOM   4812 O OG1   . THR A 1 614 ? 143.529 212.065 189.361 1.00 102.99 ? 619 THR M OG1   1 
ATOM   4813 C CG2   . THR A 1 614 ? 141.226 211.459 189.135 1.00 102.99 ? 619 THR M CG2   1 
ATOM   4814 N N     . LEU A 1 615 ? 145.217 210.079 190.798 1.00 100.50 ? 620 LEU M N     1 
ATOM   4815 C CA    . LEU A 1 615 ? 146.590 209.582 190.830 1.00 100.50 ? 620 LEU M CA    1 
ATOM   4816 C C     . LEU A 1 615 ? 146.936 209.007 192.193 1.00 100.50 ? 620 LEU M C     1 
ATOM   4817 O O     . LEU A 1 615 ? 148.056 209.178 192.664 1.00 100.50 ? 620 LEU M O     1 
ATOM   4818 C CB    . LEU A 1 615 ? 147.569 210.690 190.456 1.00 100.50 ? 620 LEU M CB    1 
ATOM   4819 C CG    . LEU A 1 615 ? 147.946 210.894 188.986 1.00 100.50 ? 620 LEU M CG    1 
ATOM   4820 C CD1   . LEU A 1 615 ? 148.577 209.641 188.411 1.00 100.50 ? 620 LEU M CD1   1 
ATOM   4821 C CD2   . LEU A 1 615 ? 146.753 211.315 188.161 1.00 100.50 ? 620 LEU M CD2   1 
ATOM   4822 N N     . PHE A 1 616 ? 145.975 208.334 192.839 1.00 102.82 ? 621 PHE M N     1 
ATOM   4823 C CA    . PHE A 1 616 ? 146.123 207.926 194.237 1.00 102.82 ? 621 PHE M CA    1 
ATOM   4824 C C     . PHE A 1 616 ? 147.453 207.236 194.493 1.00 102.82 ? 621 PHE M C     1 
ATOM   4825 O O     . PHE A 1 616 ? 148.154 207.560 195.457 1.00 102.82 ? 621 PHE M O     1 
ATOM   4826 C CB    . PHE A 1 616 ? 144.972 207.003 194.638 1.00 102.82 ? 621 PHE M CB    1 
ATOM   4827 C CG    . PHE A 1 616 ? 145.117 205.595 194.130 1.00 102.82 ? 621 PHE M CG    1 
ATOM   4828 C CD1   . PHE A 1 616 ? 144.856 205.292 192.807 1.00 102.82 ? 621 PHE M CD1   1 
ATOM   4829 C CD2   . PHE A 1 616 ? 145.531 204.579 194.971 1.00 102.82 ? 621 PHE M CD2   1 
ATOM   4830 C CE1   . PHE A 1 616 ? 144.994 204.001 192.338 1.00 102.82 ? 621 PHE M CE1   1 
ATOM   4831 C CE2   . PHE A 1 616 ? 145.670 203.289 194.505 1.00 102.82 ? 621 PHE M CE2   1 
ATOM   4832 C CZ    . PHE A 1 616 ? 145.399 203.001 193.188 1.00 102.82 ? 621 PHE M CZ    1 
ATOM   4833 N N     . ALA A 1 617 ? 147.811 206.275 193.646 1.00 102.69 ? 622 ALA M N     1 
ATOM   4834 C CA    . ALA A 1 617 ? 149.092 205.587 193.747 1.00 102.69 ? 622 ALA M CA    1 
ATOM   4835 C C     . ALA A 1 617 ? 149.327 204.907 192.410 1.00 102.69 ? 622 ALA M C     1 
ATOM   4836 O O     . ALA A 1 617 ? 148.609 203.963 192.067 1.00 102.69 ? 622 ALA M O     1 
ATOM   4837 C CB    . ALA A 1 617 ? 149.084 204.579 194.888 1.00 102.69 ? 622 ALA M CB    1 
ATOM   4838 N N     . ASN A 1 618 ? 150.307 205.385 191.653 1.00 103.03 ? 623 ASN M N     1 
ATOM   4839 C CA    . ASN A 1 618 ? 150.628 204.729 190.398 1.00 103.03 ? 623 ASN M CA    1 
ATOM   4840 C C     . ASN A 1 618 ? 152.095 204.931 190.074 1.00 103.03 ? 623 ASN M C     1 
ATOM   4841 O O     . ASN A 1 618 ? 152.737 205.864 190.561 1.00 103.03 ? 623 ASN M O     1 
ATOM   4842 C CB    . ASN A 1 618 ? 149.773 205.234 189.237 1.00 103.03 ? 623 ASN M CB    1 
ATOM   4843 C CG    . ASN A 1 618 ? 150.048 204.481 187.954 1.00 103.03 ? 623 ASN M CG    1 
ATOM   4844 O OD1   . ASN A 1 618 ? 150.549 205.044 186.984 1.00 103.03 ? 623 ASN M OD1   1 
ATOM   4845 N ND2   . ASN A 1 618 ? 149.746 203.189 187.953 1.00 103.03 ? 623 ASN M ND2   1 
ATOM   4846 N N     . TYR A 1 619 ? 152.609 204.038 189.240 1.00 101.41 ? 624 TYR M N     1 
ATOM   4847 C CA    . TYR A 1 619 ? 154.007 204.025 188.871 1.00 101.41 ? 624 TYR M CA    1 
ATOM   4848 C C     . TYR A 1 619 ? 154.177 204.372 187.402 1.00 101.41 ? 624 TYR M C     1 
ATOM   4849 O O     . TYR A 1 619 ? 154.220 205.545 187.044 1.00 101.41 ? 624 TYR M O     1 
ATOM   4850 C CB    . TYR A 1 619 ? 154.617 202.658 189.186 1.00 101.41 ? 624 TYR M CB    1 
ATOM   4851 C CG    . TYR A 1 619 ? 154.173 202.107 190.526 1.00 101.41 ? 624 TYR M CG    1 
ATOM   4852 C CD1   . TYR A 1 619 ? 154.859 202.425 191.690 1.00 101.41 ? 624 TYR M CD1   1 
ATOM   4853 C CD2   . TYR A 1 619 ? 153.058 201.284 190.627 1.00 101.41 ? 624 TYR M CD2   1 
ATOM   4854 C CE1   . TYR A 1 619 ? 154.454 201.931 192.911 1.00 101.41 ? 624 TYR M CE1   1 
ATOM   4855 C CE2   . TYR A 1 619 ? 152.648 200.788 191.846 1.00 101.41 ? 624 TYR M CE2   1 
ATOM   4856 C CZ    . TYR A 1 619 ? 153.349 201.113 192.983 1.00 101.41 ? 624 TYR M CZ    1 
ATOM   4857 O OH    . TYR A 1 619 ? 152.943 200.615 194.197 1.00 101.41 ? 624 TYR M OH    1 
ATOM   4858 N N     . GLY A 1 629 ? 162.134 192.093 194.032 1.00 66.63  ? 634 GLY M N     1 
ATOM   4859 C CA    . GLY A 1 629 ? 161.891 191.620 195.380 1.00 66.63  ? 634 GLY M CA    1 
ATOM   4860 C C     . GLY A 1 629 ? 160.812 190.559 195.422 1.00 66.63  ? 634 GLY M C     1 
ATOM   4861 O O     . GLY A 1 629 ? 159.693 190.787 194.974 1.00 66.63  ? 634 GLY M O     1 
ATOM   4862 N N     . LYS A 1 630 ? 161.161 189.385 195.941 1.00 69.34  ? 635 LYS M N     1 
ATOM   4863 C CA    . LYS A 1 630 ? 160.274 188.231 196.050 1.00 69.34  ? 635 LYS M CA    1 
ATOM   4864 C C     . LYS A 1 630 ? 159.723 187.793 194.703 1.00 69.34  ? 635 LYS M C     1 
ATOM   4865 O O     . LYS A 1 630 ? 158.865 186.904 194.645 1.00 69.34  ? 635 LYS M O     1 
ATOM   4866 C CB    . LYS A 1 630 ? 159.123 188.497 197.027 1.00 69.34  ? 635 LYS M CB    1 
ATOM   4867 C CG    . LYS A 1 630 ? 158.604 187.255 197.713 1.00 69.34  ? 635 LYS M CG    1 
ATOM   4868 C CD    . LYS A 1 630 ? 157.614 187.615 198.794 1.00 69.34  ? 635 LYS M CD    1 
ATOM   4869 C CE    . LYS A 1 630 ? 158.229 188.565 199.798 1.00 69.34  ? 635 LYS M CE    1 
ATOM   4870 N NZ    . LYS A 1 630 ? 157.317 188.793 200.947 1.00 69.34  ? 635 LYS M NZ    1 
ATOM   4871 N N     . GLY A 1 631 ? 160.216 188.375 193.616 1.00 66.62  ? 636 GLY M N     1 
ATOM   4872 C CA    . GLY A 1 631 ? 159.685 188.124 192.296 1.00 66.62  ? 636 GLY M CA    1 
ATOM   4873 C C     . GLY A 1 631 ? 158.787 189.266 191.887 1.00 66.62  ? 636 GLY M C     1 
ATOM   4874 O O     . GLY A 1 631 ? 157.610 189.305 192.254 1.00 66.62  ? 636 GLY M O     1 
ATOM   4875 N N     . LYS A 1 632 ? 159.327 190.198 191.117 1.00 67.98  ? 637 LYS M N     1 
ATOM   4876 C CA    . LYS A 1 632 ? 158.600 191.403 190.769 1.00 67.98  ? 637 LYS M CA    1 
ATOM   4877 C C     . LYS A 1 632 ? 158.592 191.593 189.264 1.00 67.98  ? 637 LYS M C     1 
ATOM   4878 O O     . LYS A 1 632 ? 159.643 191.635 188.621 1.00 67.98  ? 637 LYS M O     1 
ATOM   4879 C CB    . LYS A 1 632 ? 159.200 192.631 191.456 1.00 67.98  ? 637 LYS M CB    1 
ATOM   4880 C CG    . LYS A 1 632 ? 158.692 192.835 192.874 1.00 67.98  ? 637 LYS M CG    1 
ATOM   4881 C CD    . LYS A 1 632 ? 157.169 192.809 192.919 1.00 67.98  ? 637 LYS M CD    1 
ATOM   4882 C CE    . LYS A 1 632 ? 156.649 192.743 194.352 1.00 67.98  ? 637 LYS M CE    1 
ATOM   4883 N NZ    . LYS A 1 632 ? 155.168 192.561 194.428 1.00 67.98  ? 637 LYS M NZ    1 
ATOM   4884 N N     . ALA A 1 633 ? 157.386 191.721 188.715 1.00 73.76  ? 638 ALA M N     1 
ATOM   4885 C CA    . ALA A 1 633 ? 157.182 192.027 187.310 1.00 73.76  ? 638 ALA M CA    1 
ATOM   4886 C C     . ALA A 1 633 ? 157.085 193.524 187.064 1.00 73.76  ? 638 ALA M C     1 
ATOM   4887 O O     . ALA A 1 633 ? 156.477 193.945 186.075 1.00 73.76  ? 638 ALA M O     1 
ATOM   4888 C CB    . ALA A 1 633 ? 155.926 191.324 186.792 1.00 73.76  ? 638 ALA M CB    1 
ATOM   4889 N N     . LYS A 1 634 ? 157.675 194.335 187.941 1.00 68.39  ? 639 LYS M N     1 
ATOM   4890 C CA    . LYS A 1 634 ? 157.575 195.784 187.820 1.00 68.39  ? 639 LYS M CA    1 
ATOM   4891 C C     . LYS A 1 634 ? 158.380 196.231 186.616 1.00 68.39  ? 639 LYS M C     1 
ATOM   4892 O O     . LYS A 1 634 ? 159.590 196.424 186.708 1.00 68.39  ? 639 LYS M O     1 
ATOM   4893 C CB    . LYS A 1 634 ? 158.080 196.471 189.083 1.00 68.39  ? 639 LYS M CB    1 
ATOM   4894 C CG    . LYS A 1 634 ? 157.134 196.407 190.269 1.00 68.39  ? 639 LYS M CG    1 
ATOM   4895 C CD    . LYS A 1 634 ? 157.451 197.491 191.295 1.00 68.39  ? 639 LYS M CD    1 
ATOM   4896 C CE    . LYS A 1 634 ? 158.913 197.459 191.715 1.00 68.39  ? 639 LYS M CE    1 
ATOM   4897 N NZ    . LYS A 1 634 ? 159.226 198.431 192.797 1.00 68.39  ? 639 LYS M NZ    1 
ATOM   4898 N N     . LYS A 1 635 ? 157.717 196.412 185.481 1.00 65.78  ? 640 LYS M N     1 
ATOM   4899 C CA    . LYS A 1 635 ? 158.390 197.026 184.351 1.00 65.78  ? 640 LYS M CA    1 
ATOM   4900 C C     . LYS A 1 635 ? 158.647 198.486 184.673 1.00 65.78  ? 640 LYS M C     1 
ATOM   4901 O O     . LYS A 1 635 ? 157.843 199.140 185.336 1.00 65.78  ? 640 LYS M O     1 
ATOM   4902 C CB    . LYS A 1 635 ? 157.560 196.898 183.081 1.00 65.78  ? 640 LYS M CB    1 
ATOM   4903 C CG    . LYS A 1 635 ? 157.374 195.474 182.604 1.00 65.78  ? 640 LYS M CG    1 
ATOM   4904 C CD    . LYS A 1 635 ? 158.561 194.982 181.796 1.00 65.78  ? 640 LYS M CD    1 
ATOM   4905 C CE    . LYS A 1 635 ? 158.618 195.650 180.438 1.00 65.78  ? 640 LYS M CE    1 
ATOM   4906 N NZ    . LYS A 1 635 ? 159.711 195.108 179.589 1.00 65.78  ? 640 LYS M NZ    1 
ATOM   4907 N N     . GLY A 1 636 ? 159.781 198.987 184.222 1.00 67.76  ? 641 GLY M N     1 
ATOM   4908 C CA    . GLY A 1 636 ? 160.180 200.333 184.560 1.00 67.76  ? 641 GLY M CA    1 
ATOM   4909 C C     . GLY A 1 636 ? 159.201 201.363 184.048 1.00 67.76  ? 641 GLY M C     1 
ATOM   4910 O O     . GLY A 1 636 ? 158.219 201.071 183.371 1.00 67.76  ? 641 GLY M O     1 
ATOM   4911 N N     . SER A 1 637 ? 159.476 202.611 184.404 1.00 72.05  ? 642 SER M N     1 
ATOM   4912 C CA    . SER A 1 637 ? 158.669 203.698 183.879 1.00 72.05  ? 642 SER M CA    1 
ATOM   4913 C C     . SER A 1 637 ? 158.983 203.947 182.413 1.00 72.05  ? 642 SER M C     1 
ATOM   4914 O O     . SER A 1 637 ? 158.105 204.348 181.646 1.00 72.05  ? 642 SER M O     1 
ATOM   4915 C CB    . SER A 1 637 ? 158.892 204.956 184.707 1.00 72.05  ? 642 SER M CB    1 
ATOM   4916 O OG    . SER A 1 637 ? 158.092 204.930 185.874 1.00 72.05  ? 642 SER M OG    1 
ATOM   4917 N N     . SER A 1 638 ? 160.225 203.710 182.003 1.00 68.17  ? 643 SER M N     1 
ATOM   4918 C CA    . SER A 1 638 ? 160.604 203.944 180.618 1.00 68.17  ? 643 SER M CA    1 
ATOM   4919 C C     . SER A 1 638 ? 160.222 202.789 179.707 1.00 68.17  ? 643 SER M C     1 
ATOM   4920 O O     . SER A 1 638 ? 159.991 203.002 178.515 1.00 68.17  ? 643 SER M O     1 
ATOM   4921 C CB    . SER A 1 638 ? 162.103 204.199 180.526 1.00 68.17  ? 643 SER M CB    1 
ATOM   4922 O OG    . SER A 1 638 ? 162.517 205.079 181.550 1.00 68.17  ? 643 SER M OG    1 
ATOM   4923 N N     . PHE A 1 639 ? 160.159 201.569 180.228 1.00 66.19  ? 644 PHE M N     1 
ATOM   4924 C CA    . PHE A 1 639 ? 159.833 200.401 179.412 1.00 66.19  ? 644 PHE M CA    1 
ATOM   4925 C C     . PHE A 1 639 ? 158.318 200.217 179.321 1.00 66.19  ? 644 PHE M C     1 
ATOM   4926 O O     . PHE A 1 639 ? 157.768 199.150 179.583 1.00 66.19  ? 644 PHE M O     1 
ATOM   4927 C CB    . PHE A 1 639 ? 160.497 199.158 179.982 1.00 66.19  ? 644 PHE M CB    1 
ATOM   4928 C CG    . PHE A 1 639 ? 161.980 199.278 180.135 1.00 66.19  ? 644 PHE M CG    1 
ATOM   4929 C CD1   . PHE A 1 639 ? 162.526 199.969 181.196 1.00 66.19  ? 644 PHE M CD1   1 
ATOM   4930 C CD2   . PHE A 1 639 ? 162.827 198.680 179.229 1.00 66.19  ? 644 PHE M CD2   1 
ATOM   4931 C CE1   . PHE A 1 639 ? 163.874 200.076 181.336 1.00 66.19  ? 644 PHE M CE1   1 
ATOM   4932 C CE2   . PHE A 1 639 ? 164.176 198.783 179.375 1.00 66.19  ? 644 PHE M CE2   1 
ATOM   4933 C CZ    . PHE A 1 639 ? 164.700 199.484 180.430 1.00 66.19  ? 644 PHE M CZ    1 
ATOM   4934 N N     . GLN A 1 640 ? 157.640 201.291 178.933 1.00 76.69  ? 645 GLN M N     1 
ATOM   4935 C CA    . GLN A 1 640 ? 156.188 201.300 178.839 1.00 76.69  ? 645 GLN M CA    1 
ATOM   4936 C C     . GLN A 1 640 ? 155.790 201.603 177.407 1.00 76.69  ? 645 GLN M C     1 
ATOM   4937 O O     . GLN A 1 640 ? 156.328 202.529 176.795 1.00 76.69  ? 645 GLN M O     1 
ATOM   4938 C CB    . GLN A 1 640 ? 155.584 202.337 179.775 1.00 76.69  ? 645 GLN M CB    1 
ATOM   4939 C CG    . GLN A 1 640 ? 155.825 202.074 181.231 1.00 76.69  ? 645 GLN M CG    1 
ATOM   4940 C CD    . GLN A 1 640 ? 154.946 200.979 181.765 1.00 76.69  ? 645 GLN M CD    1 
ATOM   4941 O OE1   . GLN A 1 640 ? 154.033 200.513 181.086 1.00 76.69  ? 645 GLN M OE1   1 
ATOM   4942 N NE2   . GLN A 1 640 ? 155.210 200.560 182.994 1.00 76.69  ? 645 GLN M NE2   1 
ATOM   4943 N N     . THR A 1 641 ? 154.861 200.821 176.872 1.00 85.92  ? 646 THR M N     1 
ATOM   4944 C CA    . THR A 1 641 ? 154.413 201.017 175.506 1.00 85.92  ? 646 THR M CA    1 
ATOM   4945 C C     . THR A 1 641 ? 152.905 200.855 175.413 1.00 85.92  ? 646 THR M C     1 
ATOM   4946 O O     . THR A 1 641 ? 152.323 199.930 175.996 1.00 85.92  ? 646 THR M O     1 
ATOM   4947 C CB    . THR A 1 641 ? 155.100 200.050 174.544 1.00 85.92  ? 646 THR M CB    1 
ATOM   4948 O OG1   . THR A 1 641 ? 155.117 198.740 175.115 1.00 85.92  ? 646 THR M OG1   1 
ATOM   4949 C CG2   . THR A 1 641 ? 156.510 200.493 174.281 1.00 85.92  ? 646 THR M CG2   1 
ATOM   4950 N N     . VAL A 1 642 ? 152.293 201.773 174.661 1.00 89.57  ? 647 VAL M N     1 
ATOM   4951 C CA    . VAL A 1 642 ? 150.856 201.740 174.419 1.00 89.57  ? 647 VAL M CA    1 
ATOM   4952 C C     . VAL A 1 642 ? 150.434 200.372 173.920 1.00 89.57  ? 647 VAL M C     1 
ATOM   4953 O O     . VAL A 1 642 ? 149.393 199.843 174.319 1.00 89.57  ? 647 VAL M O     1 
ATOM   4954 C CB    . VAL A 1 642 ? 150.468 202.845 173.422 1.00 89.57  ? 647 VAL M CB    1 
ATOM   4955 C CG1   . VAL A 1 642 ? 148.972 202.942 173.312 1.00 89.57  ? 647 VAL M CG1   1 
ATOM   4956 C CG2   . VAL A 1 642 ? 151.058 204.171 173.848 1.00 89.57  ? 647 VAL M CG2   1 
ATOM   4957 N N     . SER A 1 643 ? 151.244 199.768 173.055 1.00 90.80  ? 648 SER M N     1 
ATOM   4958 C CA    . SER A 1 643 ? 150.906 198.454 172.528 1.00 90.80  ? 648 SER M CA    1 
ATOM   4959 C C     . SER A 1 643 ? 150.875 197.407 173.630 1.00 90.80  ? 648 SER M C     1 
ATOM   4960 O O     . SER A 1 643 ? 150.016 196.523 173.628 1.00 90.80  ? 648 SER M O     1 
ATOM   4961 C CB    . SER A 1 643 ? 151.898 198.060 171.438 1.00 90.80  ? 648 SER M CB    1 
ATOM   4962 O OG    . SER A 1 643 ? 153.227 198.371 171.810 1.00 90.80  ? 648 SER M OG    1 
ATOM   4963 N N     . ALA A 1 644 ? 151.793 197.497 174.591 1.00 92.49  ? 649 ALA M N     1 
ATOM   4964 C CA    . ALA A 1 644 ? 151.827 196.502 175.657 1.00 92.49  ? 649 ALA M CA    1 
ATOM   4965 C C     . ALA A 1 644 ? 150.651 196.671 176.608 1.00 92.49  ? 649 ALA M C     1 
ATOM   4966 O O     . ALA A 1 644 ? 150.008 195.683 176.997 1.00 92.49  ? 649 ALA M O     1 
ATOM   4967 C CB    . ALA A 1 644 ? 153.146 196.595 176.415 1.00 92.49  ? 649 ALA M CB    1 
ATOM   4968 N N     . LEU A 1 645 ? 150.361 197.912 177.003 1.00 94.30  ? 650 LEU M N     1 
ATOM   4969 C CA    . LEU A 1 645 ? 149.180 198.153 177.826 1.00 94.30  ? 650 LEU M CA    1 
ATOM   4970 C C     . LEU A 1 645 ? 147.919 197.684 177.116 1.00 94.30  ? 650 LEU M C     1 
ATOM   4971 O O     . LEU A 1 645 ? 147.012 197.115 177.738 1.00 94.30  ? 650 LEU M O     1 
ATOM   4972 C CB    . LEU A 1 645 ? 149.080 199.636 178.175 1.00 94.30  ? 650 LEU M CB    1 
ATOM   4973 C CG    . LEU A 1 645 ? 150.247 200.176 178.998 1.00 94.30  ? 650 LEU M CG    1 
ATOM   4974 C CD1   . LEU A 1 645 ? 150.204 201.684 179.074 1.00 94.30  ? 650 LEU M CD1   1 
ATOM   4975 C CD2   . LEU A 1 645 ? 150.230 199.575 180.388 1.00 94.30  ? 650 LEU M CD2   1 
ATOM   4976 N N     . HIS A 1 646 ? 147.859 197.893 175.804 1.00 98.52  ? 651 HIS M N     1 
ATOM   4977 C CA    . HIS A 1 646 ? 146.703 197.475 175.031 1.00 98.52  ? 651 HIS M CA    1 
ATOM   4978 C C     . HIS A 1 646 ? 146.584 195.959 174.988 1.00 98.52  ? 651 HIS M C     1 
ATOM   4979 O O     . HIS A 1 646 ? 145.481 195.418 175.097 1.00 98.52  ? 651 HIS M O     1 
ATOM   4980 C CB    . HIS A 1 646 ? 146.806 198.057 173.625 1.00 98.52  ? 651 HIS M CB    1 
ATOM   4981 C CG    . HIS A 1 646 ? 145.718 197.613 172.707 1.00 98.52  ? 651 HIS M CG    1 
ATOM   4982 N ND1   . HIS A 1 646 ? 144.499 198.249 172.640 1.00 98.52  ? 651 HIS M ND1   1 
ATOM   4983 C CD2   . HIS A 1 646 ? 145.661 196.592 171.821 1.00 98.52  ? 651 HIS M CD2   1 
ATOM   4984 C CE1   . HIS A 1 646 ? 143.738 197.642 171.749 1.00 98.52  ? 651 HIS M CE1   1 
ATOM   4985 N NE2   . HIS A 1 646 ? 144.420 196.634 171.236 1.00 98.52  ? 651 HIS M NE2   1 
ATOM   4986 N N     . ARG A 1 647 ? 147.702 195.256 174.823 1.00 97.38  ? 652 ARG M N     1 
ATOM   4987 C CA    . ARG A 1 647 ? 147.648 193.800 174.832 1.00 97.38  ? 652 ARG M CA    1 
ATOM   4988 C C     . ARG A 1 647 ? 147.166 193.280 176.177 1.00 97.38  ? 652 ARG M C     1 
ATOM   4989 O O     . ARG A 1 647 ? 146.372 192.333 176.237 1.00 97.38  ? 652 ARG M O     1 
ATOM   4990 C CB    . ARG A 1 647 ? 149.014 193.217 174.494 1.00 97.38  ? 652 ARG M CB    1 
ATOM   4991 C CG    . ARG A 1 647 ? 149.389 193.358 173.041 1.00 97.38  ? 652 ARG M CG    1 
ATOM   4992 C CD    . ARG A 1 647 ? 150.735 192.734 172.780 1.00 97.38  ? 652 ARG M CD    1 
ATOM   4993 N NE    . ARG A 1 647 ? 151.735 193.278 173.684 1.00 97.38  ? 652 ARG M NE    1 
ATOM   4994 C CZ    . ARG A 1 647 ? 153.021 192.963 173.649 1.00 97.38  ? 652 ARG M CZ    1 
ATOM   4995 N NH1   . ARG A 1 647 ? 153.470 192.106 172.747 1.00 97.38  ? 652 ARG M NH1   1 
ATOM   4996 N NH2   . ARG A 1 647 ? 153.856 193.512 174.517 1.00 97.38  ? 652 ARG M NH2   1 
ATOM   4997 N N     . GLU A 1 648 ? 147.618 193.898 177.268 1.00 103.23 ? 653 GLU M N     1 
ATOM   4998 C CA    . GLU A 1 648 ? 147.149 193.486 178.589 1.00 103.23 ? 653 GLU M CA    1 
ATOM   4999 C C     . GLU A 1 648 ? 145.645 193.703 178.739 1.00 103.23 ? 653 GLU M C     1 
ATOM   5000 O O     . GLU A 1 648 ? 144.915 192.819 179.217 1.00 103.23 ? 653 GLU M O     1 
ATOM   5001 C CB    . GLU A 1 648 ? 147.910 194.247 179.671 1.00 103.23 ? 653 GLU M CB    1 
ATOM   5002 C CG    . GLU A 1 648 ? 147.675 193.725 181.076 1.00 103.23 ? 653 GLU M CG    1 
ATOM   5003 C CD    . GLU A 1 648 ? 147.544 192.214 181.133 1.00 103.23 ? 653 GLU M CD    1 
ATOM   5004 O OE1   . GLU A 1 648 ? 146.549 191.730 181.710 1.00 103.23 ? 653 GLU M OE1   1 
ATOM   5005 O OE2   . GLU A 1 648 ? 148.439 191.511 180.617 1.00 103.23 ? 653 GLU M OE2   1 
ATOM   5006 N N     . ASN A 1 649 ? 145.165 194.883 178.343 1.00 104.73 ? 654 ASN M N     1 
ATOM   5007 C CA    . ASN A 1 649 ? 143.740 195.169 178.464 1.00 104.73 ? 654 ASN M CA    1 
ATOM   5008 C C     . ASN A 1 649 ? 142.909 194.216 177.617 1.00 104.73 ? 654 ASN M C     1 
ATOM   5009 O O     . ASN A 1 649 ? 141.852 193.747 178.051 1.00 104.73 ? 654 ASN M O     1 
ATOM   5010 C CB    . ASN A 1 649 ? 143.460 196.613 178.070 1.00 104.73 ? 654 ASN M CB    1 
ATOM   5011 C CG    . ASN A 1 649 ? 144.146 197.595 178.972 1.00 104.73 ? 654 ASN M CG    1 
ATOM   5012 O OD1   . ASN A 1 649 ? 144.600 197.240 180.054 1.00 104.73 ? 654 ASN M OD1   1 
ATOM   5013 N ND2   . ASN A 1 649 ? 144.218 198.846 178.541 1.00 104.73 ? 654 ASN M ND2   1 
ATOM   5014 N N     . LEU A 1 650 ? 143.366 193.925 176.399 1.00 107.76 ? 655 LEU M N     1 
ATOM   5015 C CA    . LEU A 1 650 ? 142.648 192.982 175.555 1.00 107.76 ? 655 LEU M CA    1 
ATOM   5016 C C     . LEU A 1 650 ? 142.626 191.602 176.185 1.00 107.76 ? 655 LEU M C     1 
ATOM   5017 O O     . LEU A 1 650 ? 141.614 190.895 176.118 1.00 107.76 ? 655 LEU M O     1 
ATOM   5018 C CB    . LEU A 1 650 ? 143.284 192.927 174.171 1.00 107.76 ? 655 LEU M CB    1 
ATOM   5019 C CG    . LEU A 1 650 ? 142.523 192.135 173.115 1.00 107.76 ? 655 LEU M CG    1 
ATOM   5020 C CD1   . LEU A 1 650 ? 141.048 192.407 173.232 1.00 107.76 ? 655 LEU M CD1   1 
ATOM   5021 C CD2   . LEU A 1 650 ? 143.006 192.523 171.741 1.00 107.76 ? 655 LEU M CD2   1 
ATOM   5022 N N     . ASN A 1 651 ? 143.731 191.200 176.809 1.00 108.61 ? 656 ASN M N     1 
ATOM   5023 C CA    . ASN A 1 651 ? 143.748 189.915 177.491 1.00 108.61 ? 656 ASN M CA    1 
ATOM   5024 C C     . ASN A 1 651 ? 142.674 189.863 178.565 1.00 108.61 ? 656 ASN M C     1 
ATOM   5025 O O     . ASN A 1 651 ? 141.908 188.897 178.646 1.00 108.61 ? 656 ASN M O     1 
ATOM   5026 C CB    . ASN A 1 651 ? 145.127 189.656 178.093 1.00 108.61 ? 656 ASN M CB    1 
ATOM   5027 C CG    . ASN A 1 651 ? 146.112 189.110 177.080 1.00 108.61 ? 656 ASN M CG    1 
ATOM   5028 O OD1   . ASN A 1 651 ? 145.724 188.580 176.041 1.00 108.61 ? 656 ASN M OD1   1 
ATOM   5029 N ND2   . ASN A 1 651 ? 147.397 189.230 177.384 1.00 108.61 ? 656 ASN M ND2   1 
ATOM   5030 N N     . LYS A 1 652 ? 142.581 190.909 179.385 1.00 112.37 ? 657 LYS M N     1 
ATOM   5031 C CA    . LYS A 1 652 ? 141.605 190.856 180.473 1.00 112.37 ? 657 LYS M CA    1 
ATOM   5032 C C     . LYS A 1 652 ? 140.168 190.994 179.980 1.00 112.37 ? 657 LYS M C     1 
ATOM   5033 O O     . LYS A 1 652 ? 139.258 190.409 180.580 1.00 112.37 ? 657 LYS M O     1 
ATOM   5034 C CB    . LYS A 1 652 ? 141.908 191.920 181.524 1.00 112.37 ? 657 LYS M CB    1 
ATOM   5035 C CG    . LYS A 1 652 ? 141.533 193.330 181.141 1.00 112.37 ? 657 LYS M CG    1 
ATOM   5036 C CD    . LYS A 1 652 ? 141.936 194.282 182.239 1.00 112.37 ? 657 LYS M CD    1 
ATOM   5037 C CE    . LYS A 1 652 ? 141.354 193.834 183.558 1.00 112.37 ? 657 LYS M CE    1 
ATOM   5038 N NZ    . LYS A 1 652 ? 139.887 193.613 183.449 1.00 112.37 ? 657 LYS M NZ    1 
ATOM   5039 N N     . LEU A 1 653 ? 139.941 191.720 178.886 1.00 114.00 ? 658 LEU M N     1 
ATOM   5040 C CA    . LEU A 1 653 ? 138.610 191.751 178.292 1.00 114.00 ? 658 LEU M CA    1 
ATOM   5041 C C     . LEU A 1 653 ? 138.206 190.377 177.779 1.00 114.00 ? 658 LEU M C     1 
ATOM   5042 O O     . LEU A 1 653 ? 137.061 189.947 177.973 1.00 114.00 ? 658 LEU M O     1 
ATOM   5043 C CB    . LEU A 1 653 ? 138.566 192.771 177.160 1.00 114.00 ? 658 LEU M CB    1 
ATOM   5044 C CG    . LEU A 1 653 ? 137.290 192.844 176.326 1.00 114.00 ? 658 LEU M CG    1 
ATOM   5045 C CD1   . LEU A 1 653 ? 136.086 193.035 177.223 1.00 114.00 ? 658 LEU M CD1   1 
ATOM   5046 C CD2   . LEU A 1 653 ? 137.386 193.978 175.323 1.00 114.00 ? 658 LEU M CD2   1 
ATOM   5047 N N     . MET A 1 654 ? 139.128 189.676 177.120 1.00 115.69 ? 659 MET M N     1 
ATOM   5048 C CA    . MET A 1 654 ? 138.839 188.310 176.706 1.00 115.69 ? 659 MET M CA    1 
ATOM   5049 C C     . MET A 1 654 ? 138.557 187.425 177.909 1.00 115.69 ? 659 MET M C     1 
ATOM   5050 O O     . MET A 1 654 ? 137.664 186.576 177.862 1.00 115.69 ? 659 MET M O     1 
ATOM   5051 C CB    . MET A 1 654 ? 139.995 187.744 175.886 1.00 115.69 ? 659 MET M CB    1 
ATOM   5052 C CG    . MET A 1 654 ? 140.212 188.427 174.553 1.00 115.69 ? 659 MET M CG    1 
ATOM   5053 S SD    . MET A 1 654 ? 138.753 188.411 173.501 1.00 115.69 ? 659 MET M SD    1 
ATOM   5054 C CE    . MET A 1 654 ? 138.231 190.113 173.644 1.00 115.69 ? 659 MET M CE    1 
ATOM   5055 N N     . THR A 1 655 ? 139.302 187.605 178.999 1.00 116.17 ? 660 THR M N     1 
ATOM   5056 C CA    . THR A 1 655 ? 139.019 186.805 180.185 1.00 116.17 ? 660 THR M CA    1 
ATOM   5057 C C     . THR A 1 655 ? 137.657 187.115 180.783 1.00 116.17 ? 660 THR M C     1 
ATOM   5058 O O     . THR A 1 655 ? 137.044 186.226 181.378 1.00 116.17 ? 660 THR M O     1 
ATOM   5059 C CB    . THR A 1 655 ? 140.088 187.001 181.258 1.00 116.17 ? 660 THR M CB    1 
ATOM   5060 O OG1   . THR A 1 655 ? 139.972 188.315 181.819 1.00 116.17 ? 660 THR M OG1   1 
ATOM   5061 C CG2   . THR A 1 655 ? 141.479 186.771 180.700 1.00 116.17 ? 660 THR M CG2   1 
ATOM   5062 N N     . ASN A 1 656 ? 137.161 188.339 180.627 1.00 118.46 ? 661 ASN M N     1 
ATOM   5063 C CA    . ASN A 1 656 ? 135.814 188.624 181.111 1.00 118.46 ? 661 ASN M CA    1 
ATOM   5064 C C     . ASN A 1 656 ? 134.737 188.061 180.193 1.00 118.46 ? 661 ASN M C     1 
ATOM   5065 O O     . ASN A 1 656 ? 133.687 187.622 180.670 1.00 118.46 ? 661 ASN M O     1 
ATOM   5066 C CB    . ASN A 1 656 ? 135.601 190.129 181.283 1.00 118.46 ? 661 ASN M CB    1 
ATOM   5067 C CG    . ASN A 1 656 ? 136.386 190.695 182.441 1.00 118.46 ? 661 ASN M CG    1 
ATOM   5068 O OD1   . ASN A 1 656 ? 137.272 191.529 182.263 1.00 118.46 ? 661 ASN M OD1   1 
ATOM   5069 N ND2   . ASN A 1 656 ? 136.072 190.235 183.641 1.00 118.46 ? 661 ASN M ND2   1 
ATOM   5070 N N     . LEU A 1 657 ? 134.976 188.060 178.882 1.00 122.34 ? 662 LEU M N     1 
ATOM   5071 C CA    . LEU A 1 657 ? 133.955 187.565 177.963 1.00 122.34 ? 662 LEU M CA    1 
ATOM   5072 C C     . LEU A 1 657 ? 133.904 186.045 177.898 1.00 122.34 ? 662 LEU M C     1 
ATOM   5073 O O     . LEU A 1 657 ? 132.816 185.475 177.787 1.00 122.34 ? 662 LEU M O     1 
ATOM   5074 C CB    . LEU A 1 657 ? 134.184 188.121 176.562 1.00 122.34 ? 662 LEU M CB    1 
ATOM   5075 C CG    . LEU A 1 657 ? 133.705 189.551 176.346 1.00 122.34 ? 662 LEU M CG    1 
ATOM   5076 C CD1   . LEU A 1 657 ? 133.638 189.852 174.863 1.00 122.34 ? 662 LEU M CD1   1 
ATOM   5077 C CD2   . LEU A 1 657 ? 132.359 189.767 177.000 1.00 122.34 ? 662 LEU M CD2   1 
ATOM   5078 N N     . ARG A 1 658 ? 135.052 185.373 177.968 1.00 123.63 ? 663 ARG M N     1 
ATOM   5079 C CA    . ARG A 1 658 ? 135.108 183.940 177.716 1.00 123.63 ? 663 ARG M CA    1 
ATOM   5080 C C     . ARG A 1 658 ? 134.426 183.113 178.792 1.00 123.63 ? 663 ARG M C     1 
ATOM   5081 O O     . ARG A 1 658 ? 134.361 181.887 178.654 1.00 123.63 ? 663 ARG M O     1 
ATOM   5082 C CB    . ARG A 1 658 ? 136.559 183.494 177.575 1.00 123.63 ? 663 ARG M CB    1 
ATOM   5083 C CG    . ARG A 1 658 ? 137.221 183.981 176.308 1.00 123.63 ? 663 ARG M CG    1 
ATOM   5084 C CD    . ARG A 1 658 ? 138.615 183.423 176.164 1.00 123.63 ? 663 ARG M CD    1 
ATOM   5085 N NE    . ARG A 1 658 ? 139.410 184.219 175.237 1.00 123.63 ? 663 ARG M NE    1 
ATOM   5086 C CZ    . ARG A 1 658 ? 140.551 183.810 174.697 1.00 123.63 ? 663 ARG M CZ    1 
ATOM   5087 N NH1   . ARG A 1 658 ? 141.025 182.606 174.986 1.00 123.63 ? 663 ARG M NH1   1 
ATOM   5088 N NH2   . ARG A 1 658 ? 141.213 184.601 173.865 1.00 123.63 ? 663 ARG M NH2   1 
ATOM   5089 N N     . SER A 1 659 ? 133.933 183.739 179.855 1.00 127.69 ? 664 SER M N     1 
ATOM   5090 C CA    . SER A 1 659 ? 133.185 183.038 180.887 1.00 127.69 ? 664 SER M CA    1 
ATOM   5091 C C     . SER A 1 659 ? 131.678 183.105 180.678 1.00 127.69 ? 664 SER M C     1 
ATOM   5092 O O     . SER A 1 659 ? 130.933 182.528 181.475 1.00 127.69 ? 664 SER M O     1 
ATOM   5093 C CB    . SER A 1 659 ? 133.538 183.601 182.265 1.00 127.69 ? 664 SER M CB    1 
ATOM   5094 O OG    . SER A 1 659 ? 134.936 183.773 182.392 1.00 127.69 ? 664 SER M OG    1 
ATOM   5095 N N     . THR A 1 660 ? 131.211 183.788 179.633 1.00 134.73 ? 665 THR M N     1 
ATOM   5096 C CA    . THR A 1 660 ? 129.789 183.971 179.386 1.00 134.73 ? 665 THR M CA    1 
ATOM   5097 C C     . THR A 1 660 ? 129.425 183.430 178.011 1.00 134.73 ? 665 THR M C     1 
ATOM   5098 O O     . THR A 1 660 ? 130.185 183.589 177.052 1.00 134.73 ? 665 THR M O     1 
ATOM   5099 C CB    . THR A 1 660 ? 129.402 185.444 179.457 1.00 134.73 ? 665 THR M CB    1 
ATOM   5100 O OG1   . THR A 1 660 ? 129.915 186.122 178.306 1.00 134.73 ? 665 THR M OG1   1 
ATOM   5101 C CG2   . THR A 1 660 ? 130.011 186.081 180.687 1.00 134.73 ? 665 THR M CG2   1 
ATOM   5102 N N     . HIS A 1 661 ? 128.255 182.812 177.915 1.00 140.74 ? 666 HIS M N     1 
ATOM   5103 C CA    . HIS A 1 661 ? 127.767 182.317 176.632 1.00 140.74 ? 666 HIS M CA    1 
ATOM   5104 C C     . HIS A 1 661 ? 127.348 183.495 175.761 1.00 140.74 ? 666 HIS M C     1 
ATOM   5105 O O     . HIS A 1 661 ? 126.445 184.248 176.143 1.00 140.74 ? 666 HIS M O     1 
ATOM   5106 C CB    . HIS A 1 661 ? 126.604 181.356 176.846 1.00 140.74 ? 666 HIS M CB    1 
ATOM   5107 C CG    . HIS A 1 661 ? 126.037 180.802 175.577 1.00 140.74 ? 666 HIS M CG    1 
ATOM   5108 N ND1   . HIS A 1 661 ? 124.944 181.356 174.946 1.00 140.74 ? 666 HIS M ND1   1 
ATOM   5109 C CD2   . HIS A 1 661 ? 126.413 179.745 174.820 1.00 140.74 ? 666 HIS M CD2   1 
ATOM   5110 C CE1   . HIS A 1 661 ? 124.673 180.664 173.854 1.00 140.74 ? 666 HIS M CE1   1 
ATOM   5111 N NE2   . HIS A 1 661 ? 125.549 179.681 173.754 1.00 140.74 ? 666 HIS M NE2   1 
ATOM   5112 N N     . PRO A 1 662 ? 127.957 183.689 174.599 1.00 141.79 ? 667 PRO M N     1 
ATOM   5113 C CA    . PRO A 1 662 ? 127.803 184.947 173.867 1.00 141.79 ? 667 PRO M CA    1 
ATOM   5114 C C     . PRO A 1 662 ? 126.684 184.924 172.836 1.00 141.79 ? 667 PRO M C     1 
ATOM   5115 O O     . PRO A 1 662 ? 126.256 183.874 172.355 1.00 141.79 ? 667 PRO M O     1 
ATOM   5116 C CB    . PRO A 1 662 ? 129.160 185.083 173.169 1.00 141.79 ? 667 PRO M CB    1 
ATOM   5117 C CG    . PRO A 1 662 ? 129.508 183.662 172.847 1.00 141.79 ? 667 PRO M CG    1 
ATOM   5118 C CD    . PRO A 1 662 ? 128.954 182.810 173.969 1.00 141.79 ? 667 PRO M CD    1 
ATOM   5119 N N     . HIS A 1 663 ? 126.235 186.128 172.485 1.00 142.61 ? 668 HIS M N     1 
ATOM   5120 C CA    . HIS A 1 663 ? 125.279 186.324 171.407 1.00 142.61 ? 668 HIS M CA    1 
ATOM   5121 C C     . HIS A 1 663 ? 125.661 187.578 170.639 1.00 142.61 ? 668 HIS M C     1 
ATOM   5122 O O     . HIS A 1 663 ? 126.191 188.535 171.209 1.00 142.61 ? 668 HIS M O     1 
ATOM   5123 C CB    . HIS A 1 663 ? 123.847 186.437 171.931 1.00 142.61 ? 668 HIS M CB    1 
ATOM   5124 C CG    . HIS A 1 663 ? 123.445 185.306 172.822 1.00 142.61 ? 668 HIS M CG    1 
ATOM   5125 N ND1   . HIS A 1 663 ? 123.147 185.481 174.155 1.00 142.61 ? 668 HIS M ND1   1 
ATOM   5126 C CD2   . HIS A 1 663 ? 123.309 183.982 172.575 1.00 142.61 ? 668 HIS M CD2   1 
ATOM   5127 C CE1   . HIS A 1 663 ? 122.840 184.314 174.689 1.00 142.61 ? 668 HIS M CE1   1 
ATOM   5128 N NE2   . HIS A 1 663 ? 122.930 183.388 173.752 1.00 142.61 ? 668 HIS M NE2   1 
ATOM   5129 N N     . PHE A 1 664 ? 125.362 187.576 169.343 1.00 145.43 ? 669 PHE M N     1 
ATOM   5130 C CA    . PHE A 1 664 ? 125.931 188.540 168.412 1.00 145.43 ? 669 PHE M CA    1 
ATOM   5131 C C     . PHE A 1 664 ? 124.841 189.250 167.625 1.00 145.43 ? 669 PHE M C     1 
ATOM   5132 O O     . PHE A 1 664 ? 123.904 188.618 167.131 1.00 145.43 ? 669 PHE M O     1 
ATOM   5133 C CB    . PHE A 1 664 ? 126.898 187.835 167.466 1.00 145.43 ? 669 PHE M CB    1 
ATOM   5134 C CG    . PHE A 1 664 ? 127.795 186.857 168.158 1.00 145.43 ? 669 PHE M CG    1 
ATOM   5135 C CD1   . PHE A 1 664 ? 127.428 185.531 168.287 1.00 145.43 ? 669 PHE M CD1   1 
ATOM   5136 C CD2   . PHE A 1 664 ? 128.996 187.269 168.704 1.00 145.43 ? 669 PHE M CD2   1 
ATOM   5137 C CE1   . PHE A 1 664 ? 128.251 184.631 168.939 1.00 145.43 ? 669 PHE M CE1   1 
ATOM   5138 C CE2   . PHE A 1 664 ? 129.822 186.372 169.352 1.00 145.43 ? 669 PHE M CE2   1 
ATOM   5139 C CZ    . PHE A 1 664 ? 129.450 185.053 169.470 1.00 145.43 ? 669 PHE M CZ    1 
ATOM   5140 N N     . VAL A 1 665 ? 124.986 190.567 167.499 1.00 146.99 ? 670 VAL M N     1 
ATOM   5141 C CA    . VAL A 1 665 ? 124.028 191.418 166.806 1.00 146.99 ? 670 VAL M CA    1 
ATOM   5142 C C     . VAL A 1 665 ? 124.782 192.256 165.787 1.00 146.99 ? 670 VAL M C     1 
ATOM   5143 O O     . VAL A 1 665 ? 125.754 192.934 166.135 1.00 146.99 ? 670 VAL M O     1 
ATOM   5144 C CB    . VAL A 1 665 ? 123.263 192.327 167.784 1.00 146.99 ? 670 VAL M CB    1 
ATOM   5145 C CG1   . VAL A 1 665 ? 122.397 193.310 167.023 1.00 146.99 ? 670 VAL M CG1   1 
ATOM   5146 C CG2   . VAL A 1 665 ? 122.428 191.494 168.732 1.00 146.99 ? 670 VAL M CG2   1 
ATOM   5147 N N     . ARG A 1 666 ? 124.330 192.225 164.539 1.00 149.94 ? 671 ARG M N     1 
ATOM   5148 C CA    . ARG A 1 666 ? 125.010 192.899 163.443 1.00 149.94 ? 671 ARG M CA    1 
ATOM   5149 C C     . ARG A 1 666 ? 124.120 194.000 162.887 1.00 149.94 ? 671 ARG M C     1 
ATOM   5150 O O     . ARG A 1 666 ? 123.003 193.729 162.438 1.00 149.94 ? 671 ARG M O     1 
ATOM   5151 C CB    . ARG A 1 666 ? 125.376 191.902 162.342 1.00 149.94 ? 671 ARG M CB    1 
ATOM   5152 C CG    . ARG A 1 666 ? 126.261 190.749 162.803 1.00 149.94 ? 671 ARG M CG    1 
ATOM   5153 C CD    . ARG A 1 666 ? 127.328 191.203 163.786 1.00 149.94 ? 671 ARG M CD    1 
ATOM   5154 N NE    . ARG A 1 666 ? 128.193 190.102 164.199 1.00 149.94 ? 671 ARG M NE    1 
ATOM   5155 C CZ    . ARG A 1 666 ? 128.694 189.968 165.423 1.00 149.94 ? 671 ARG M CZ    1 
ATOM   5156 N NH1   . ARG A 1 666 ? 128.420 190.865 166.358 1.00 149.94 ? 671 ARG M NH1   1 
ATOM   5157 N NH2   . ARG A 1 666 ? 129.471 188.938 165.718 1.00 149.94 ? 671 ARG M NH2   1 
ATOM   5158 N N     . CYS A 1 667 ? 124.619 195.232 162.901 1.00 151.85 ? 672 CYS M N     1 
ATOM   5159 C CA    . CYS A 1 667 ? 123.879 196.393 162.428 1.00 151.85 ? 672 CYS M CA    1 
ATOM   5160 C C     . CYS A 1 667 ? 124.517 196.922 161.153 1.00 151.85 ? 672 CYS M C     1 
ATOM   5161 O O     . CYS A 1 667 ? 125.726 197.171 161.119 1.00 151.85 ? 672 CYS M O     1 
ATOM   5162 C CB    . CYS A 1 667 ? 123.842 197.492 163.488 1.00 151.85 ? 672 CYS M CB    1 
ATOM   5163 S SG    . CYS A 1 667 ? 123.349 199.101 162.845 1.00 151.85 ? 672 CYS M SG    1 
ATOM   5164 N N     . ILE A 1 668 ? 123.706 197.101 160.112 1.00 156.42 ? 673 ILE M N     1 
ATOM   5165 C CA    . ILE A 1 668 ? 124.171 197.571 158.813 1.00 156.42 ? 673 ILE M CA    1 
ATOM   5166 C C     . ILE A 1 668 ? 123.417 198.838 158.449 1.00 156.42 ? 673 ILE M C     1 
ATOM   5167 O O     . ILE A 1 668 ? 122.191 198.897 158.586 1.00 156.42 ? 673 ILE M O     1 
ATOM   5168 C CB    . ILE A 1 668 ? 123.976 196.518 157.711 1.00 156.42 ? 673 ILE M CB    1 
ATOM   5169 C CG1   . ILE A 1 668 ? 124.359 195.129 158.202 1.00 156.42 ? 673 ILE M CG1   1 
ATOM   5170 C CG2   . ILE A 1 668 ? 124.777 196.885 156.480 1.00 156.42 ? 673 ILE M CG2   1 
ATOM   5171 C CD1   . ILE A 1 668 ? 124.115 194.065 157.165 1.00 156.42 ? 673 ILE M CD1   1 
ATOM   5172 N N     . ILE A 1 669 ? 124.145 199.837 157.976 1.00 161.35 ? 674 ILE M N     1 
ATOM   5173 C CA    . ILE A 1 669 ? 123.513 201.005 157.364 1.00 161.35 ? 674 ILE M CA    1 
ATOM   5174 C C     . ILE A 1 669 ? 123.144 200.654 155.924 1.00 161.35 ? 674 ILE M C     1 
ATOM   5175 O O     . ILE A 1 669 ? 123.955 200.029 155.221 1.00 161.35 ? 674 ILE M O     1 
ATOM   5176 C CB    . ILE A 1 669 ? 124.448 202.215 157.429 1.00 161.35 ? 674 ILE M CB    1 
ATOM   5177 C CG1   . ILE A 1 669 ? 123.700 203.511 157.118 1.00 161.35 ? 674 ILE M CG1   1 
ATOM   5178 C CG2   . ILE A 1 669 ? 125.681 202.039 156.545 1.00 161.35 ? 674 ILE M CG2   1 
ATOM   5179 C CD1   . ILE A 1 669 ? 122.775 203.936 158.222 1.00 161.35 ? 674 ILE M CD1   1 
ATOM   5180 N N     . PRO A 1 670 ? 121.924 200.962 155.465 1.00 165.60 ? 675 PRO M N     1 
ATOM   5181 C CA    . PRO A 1 670 ? 121.552 200.589 154.094 1.00 165.60 ? 675 PRO M CA    1 
ATOM   5182 C C     . PRO A 1 670 ? 122.140 201.537 153.067 1.00 165.60 ? 675 PRO M C     1 
ATOM   5183 O O     . PRO A 1 670 ? 122.533 201.119 151.974 1.00 165.60 ? 675 PRO M O     1 
ATOM   5184 C CB    . PRO A 1 670 ? 120.021 200.656 154.115 1.00 165.60 ? 675 PRO M CB    1 
ATOM   5185 C CG    . PRO A 1 670 ? 119.713 201.660 155.156 1.00 165.60 ? 675 PRO M CG    1 
ATOM   5186 C CD    . PRO A 1 670 ? 120.792 201.552 156.200 1.00 165.60 ? 675 PRO M CD    1 
ATOM   5187 N N     . ASN A 1 671 ? 122.220 202.816 153.420 1.00 168.05 ? 676 ASN M N     1 
ATOM   5188 C CA    . ASN A 1 671 ? 122.763 203.823 152.525 1.00 168.05 ? 676 ASN M CA    1 
ATOM   5189 C C     . ASN A 1 671 ? 123.262 204.998 153.346 1.00 168.05 ? 676 ASN M C     1 
ATOM   5190 O O     . ASN A 1 671 ? 122.783 205.247 154.455 1.00 168.05 ? 676 ASN M O     1 
ATOM   5191 C CB    . ASN A 1 671 ? 121.721 204.298 151.511 1.00 168.05 ? 676 ASN M CB    1 
ATOM   5192 C CG    . ASN A 1 671 ? 120.427 204.724 152.167 1.00 168.05 ? 676 ASN M CG    1 
ATOM   5193 O OD1   . ASN A 1 671 ? 120.265 204.618 153.381 1.00 168.05 ? 676 ASN M OD1   1 
ATOM   5194 N ND2   . ASN A 1 671 ? 119.495 205.212 151.363 1.00 168.05 ? 676 ASN M ND2   1 
ATOM   5195 N N     . GLU A 1 672 ? 124.231 205.722 152.786 1.00 168.32 ? 677 GLU M N     1 
ATOM   5196 C CA    . GLU A 1 672 ? 124.784 206.870 153.491 1.00 168.32 ? 677 GLU M CA    1 
ATOM   5197 C C     . GLU A 1 672 ? 123.779 208.006 153.581 1.00 168.32 ? 677 GLU M C     1 
ATOM   5198 O O     . GLU A 1 672 ? 123.812 208.789 154.537 1.00 168.32 ? 677 GLU M O     1 
ATOM   5199 C CB    . GLU A 1 672 ? 126.062 207.340 152.801 1.00 168.32 ? 677 GLU M CB    1 
ATOM   5200 C CG    . GLU A 1 672 ? 127.271 206.483 153.122 1.00 168.32 ? 677 GLU M CG    1 
ATOM   5201 C CD    . GLU A 1 672 ? 128.190 206.313 151.938 1.00 168.32 ? 677 GLU M CD    1 
ATOM   5202 O OE1   . GLU A 1 672 ? 127.796 205.620 150.979 1.00 168.32 ? 677 GLU M OE1   1 
ATOM   5203 O OE2   . GLU A 1 672 ? 129.305 206.868 151.967 1.00 168.32 ? 677 GLU M OE2   1 
ATOM   5204 N N     . THR A 1 673 ? 122.879 208.107 152.613 1.00 168.78 ? 678 THR M N     1 
ATOM   5205 C CA    . THR A 1 673 ? 121.846 209.126 152.649 1.00 168.78 ? 678 THR M CA    1 
ATOM   5206 C C     . THR A 1 673 ? 120.732 208.681 153.581 1.00 168.78 ? 678 THR M C     1 
ATOM   5207 O O     . THR A 1 673 ? 120.476 207.487 153.752 1.00 168.78 ? 678 THR M O     1 
ATOM   5208 C CB    . THR A 1 673 ? 121.281 209.389 151.254 1.00 168.78 ? 678 THR M CB    1 
ATOM   5209 O OG1   . THR A 1 673 ? 120.295 208.397 150.946 1.00 168.78 ? 678 THR M OG1   1 
ATOM   5210 C CG2   . THR A 1 673 ? 122.387 209.326 150.211 1.00 168.78 ? 678 THR M CG2   1 
ATOM   5211 N N     . LYS A 1 674 ? 120.065 209.658 154.189 1.00 167.90 ? 679 LYS M N     1 
ATOM   5212 C CA    . LYS A 1 674 ? 118.968 209.337 155.089 1.00 167.90 ? 679 LYS M CA    1 
ATOM   5213 C C     . LYS A 1 674 ? 117.721 208.881 154.344 1.00 167.90 ? 679 LYS M C     1 
ATOM   5214 O O     . LYS A 1 674 ? 116.739 208.498 154.989 1.00 167.90 ? 679 LYS M O     1 
ATOM   5215 C CB    . LYS A 1 674 ? 118.655 210.542 155.975 1.00 167.90 ? 679 LYS M CB    1 
ATOM   5216 C CG    . LYS A 1 674 ? 118.165 210.168 157.359 1.00 167.90 ? 679 LYS M CG    1 
ATOM   5217 C CD    . LYS A 1 674 ? 119.022 209.065 157.964 1.00 167.90 ? 679 LYS M CD    1 
ATOM   5218 C CE    . LYS A 1 674 ? 120.432 209.543 158.273 1.00 167.90 ? 679 LYS M CE    1 
ATOM   5219 N NZ    . LYS A 1 674 ? 121.309 208.414 158.685 1.00 167.90 ? 679 LYS M NZ    1 
ATOM   5220 N N     . SER A 1 675 ? 117.742 208.909 153.019 1.00 169.99 ? 680 SER M N     1 
ATOM   5221 C CA    . SER A 1 675 ? 116.638 208.398 152.216 1.00 169.99 ? 680 SER M CA    1 
ATOM   5222 C C     . SER A 1 675 ? 116.566 206.881 152.319 1.00 169.99 ? 680 SER M C     1 
ATOM   5223 O O     . SER A 1 675 ? 117.537 206.201 151.969 1.00 169.99 ? 680 SER M O     1 
ATOM   5224 C CB    . SER A 1 675 ? 116.821 208.817 150.762 1.00 169.99 ? 680 SER M CB    1 
ATOM   5225 O OG    . SER A 1 675 ? 117.775 207.989 150.119 1.00 169.99 ? 680 SER M OG    1 
ATOM   5226 N N     . PRO A 1 676 ? 115.457 206.312 152.781 1.00 168.88 ? 681 PRO M N     1 
ATOM   5227 C CA    . PRO A 1 676 ? 115.350 204.848 152.857 1.00 168.88 ? 681 PRO M CA    1 
ATOM   5228 C C     . PRO A 1 676 ? 115.188 204.195 151.495 1.00 168.88 ? 681 PRO M C     1 
ATOM   5229 O O     . PRO A 1 676 ? 115.219 204.865 150.459 1.00 168.88 ? 681 PRO M O     1 
ATOM   5230 C CB    . PRO A 1 676 ? 114.104 204.624 153.726 1.00 168.88 ? 681 PRO M CB    1 
ATOM   5231 C CG    . PRO A 1 676 ? 113.766 205.968 154.311 1.00 168.88 ? 681 PRO M CG    1 
ATOM   5232 C CD    . PRO A 1 676 ? 114.285 206.986 153.358 1.00 168.88 ? 681 PRO M CD    1 
ATOM   5233 N N     . GLY A 1 677 ? 115.031 202.875 151.495 1.00 168.47 ? 682 GLY M N     1 
ATOM   5234 C CA    . GLY A 1 677 ? 114.765 202.130 150.280 1.00 168.47 ? 682 GLY M CA    1 
ATOM   5235 C C     . GLY A 1 677 ? 115.974 201.970 149.384 1.00 168.47 ? 682 GLY M C     1 
ATOM   5236 O O     . GLY A 1 677 ? 116.450 200.852 149.158 1.00 168.47 ? 682 GLY M O     1 
ATOM   5237 N N     . VAL A 1 678 ? 116.478 203.087 148.857 1.00 169.10 ? 683 VAL M N     1 
ATOM   5238 C CA    . VAL A 1 678 ? 117.661 203.038 148.011 1.00 169.10 ? 683 VAL M CA    1 
ATOM   5239 C C     . VAL A 1 678 ? 118.887 202.801 148.882 1.00 169.10 ? 683 VAL M C     1 
ATOM   5240 O O     . VAL A 1 678 ? 119.020 203.372 149.972 1.00 169.10 ? 683 VAL M O     1 
ATOM   5241 C CB    . VAL A 1 678 ? 117.785 204.328 147.182 1.00 169.10 ? 683 VAL M CB    1 
ATOM   5242 C CG1   . VAL A 1 678 ? 117.804 205.548 148.082 1.00 169.10 ? 683 VAL M CG1   1 
ATOM   5243 C CG2   . VAL A 1 678 ? 119.017 204.281 146.297 1.00 169.10 ? 683 VAL M CG2   1 
ATOM   5244 N N     . MET A 1 679 ? 119.787 201.946 148.410 1.00 168.50 ? 684 MET M N     1 
ATOM   5245 C CA    . MET A 1 679 ? 120.920 201.498 149.202 1.00 168.50 ? 684 MET M CA    1 
ATOM   5246 C C     . MET A 1 679 ? 122.208 201.831 148.468 1.00 168.50 ? 684 MET M C     1 
ATOM   5247 O O     . MET A 1 679 ? 122.219 202.583 147.490 1.00 168.50 ? 684 MET M O     1 
ATOM   5248 C CB    . MET A 1 679 ? 120.844 199.993 149.476 1.00 168.50 ? 684 MET M CB    1 
ATOM   5249 C CG    . MET A 1 679 ? 119.508 199.524 149.984 1.00 168.50 ? 684 MET M CG    1 
ATOM   5250 S SD    . MET A 1 679 ? 119.424 197.732 150.077 1.00 168.50 ? 684 MET M SD    1 
ATOM   5251 C CE    . MET A 1 679 ? 117.653 197.530 150.126 1.00 168.50 ? 684 MET M CE    1 
ATOM   5252 N N     . ASP A 1 680 ? 123.309 201.264 148.954 1.00 167.55 ? 685 ASP M N     1 
ATOM   5253 C CA    . ASP A 1 680 ? 124.605 201.388 148.296 1.00 167.55 ? 685 ASP M CA    1 
ATOM   5254 C C     . ASP A 1 680 ? 125.304 200.035 148.435 1.00 167.55 ? 685 ASP M C     1 
ATOM   5255 O O     . ASP A 1 680 ? 125.772 199.674 149.522 1.00 167.55 ? 685 ASP M O     1 
ATOM   5256 C CB    . ASP A 1 680 ? 125.419 202.525 148.905 1.00 167.55 ? 685 ASP M CB    1 
ATOM   5257 C CG    . ASP A 1 680 ? 126.438 203.087 147.943 1.00 167.55 ? 685 ASP M CG    1 
ATOM   5258 O OD1   . ASP A 1 680 ? 126.436 202.664 146.766 1.00 167.55 ? 685 ASP M OD1   1 
ATOM   5259 O OD2   . ASP A 1 680 ? 127.240 203.947 148.366 1.00 167.55 ? 685 ASP M OD2   1 
ATOM   5260 N N     . ASN A 1 681 ? 125.352 199.282 147.338 1.00 168.28 ? 686 ASN M N     1 
ATOM   5261 C CA    . ASN A 1 681 ? 126.006 197.975 147.348 1.00 168.28 ? 686 ASN M CA    1 
ATOM   5262 C C     . ASN A 1 681 ? 127.448 197.997 147.841 1.00 168.28 ? 686 ASN M C     1 
ATOM   5263 O O     . ASN A 1 681 ? 127.831 197.061 148.564 1.00 168.28 ? 686 ASN M O     1 
ATOM   5264 C CB    . ASN A 1 681 ? 125.942 197.364 145.943 1.00 168.28 ? 686 ASN M CB    1 
ATOM   5265 C CG    . ASN A 1 681 ? 124.567 197.469 145.333 1.00 168.28 ? 686 ASN M CG    1 
ATOM   5266 O OD1   . ASN A 1 681 ? 124.140 198.548 144.926 1.00 168.28 ? 686 ASN M OD1   1 
ATOM   5267 N ND2   . ASN A 1 681 ? 123.866 196.345 145.256 1.00 168.28 ? 686 ASN M ND2   1 
ATOM   5268 N N     . PRO A 1 682 ? 128.296 198.969 147.485 1.00 164.16 ? 687 PRO M N     1 
ATOM   5269 C CA    . PRO A 1 682 ? 129.643 198.975 148.071 1.00 164.16 ? 687 PRO M CA    1 
ATOM   5270 C C     . PRO A 1 682 ? 129.628 199.097 149.578 1.00 164.16 ? 687 PRO M C     1 
ATOM   5271 O O     . PRO A 1 682 ? 130.404 198.412 150.253 1.00 164.16 ? 687 PRO M O     1 
ATOM   5272 C CB    . PRO A 1 682 ? 130.314 200.183 147.397 1.00 164.16 ? 687 PRO M CB    1 
ATOM   5273 C CG    . PRO A 1 682 ? 129.210 200.999 146.895 1.00 164.16 ? 687 PRO M CG    1 
ATOM   5274 C CD    . PRO A 1 682 ? 128.162 200.030 146.475 1.00 164.16 ? 687 PRO M CD    1 
ATOM   5275 N N     . LEU A 1 683 ? 128.750 199.935 150.129 1.00 161.50 ? 688 LEU M N     1 
ATOM   5276 C CA    . LEU A 1 683 ? 128.678 200.064 151.579 1.00 161.50 ? 688 LEU M CA    1 
ATOM   5277 C C     . LEU A 1 683 ? 128.169 198.781 152.214 1.00 161.50 ? 688 LEU M C     1 
ATOM   5278 O O     . LEU A 1 683 ? 128.640 198.380 153.285 1.00 161.50 ? 688 LEU M O     1 
ATOM   5279 C CB    . LEU A 1 683 ? 127.801 201.253 151.963 1.00 161.50 ? 688 LEU M CB    1 
ATOM   5280 C CG    . LEU A 1 683 ? 128.526 202.596 152.101 1.00 161.50 ? 688 LEU M CG    1 
ATOM   5281 C CD1   . LEU A 1 683 ? 129.426 202.585 153.313 1.00 161.50 ? 688 LEU M CD1   1 
ATOM   5282 C CD2   . LEU A 1 683 ? 129.343 202.901 150.860 1.00 161.50 ? 688 LEU M CD2   1 
ATOM   5283 N N     . VAL A 1 684 ? 127.234 198.100 151.552 1.00 161.73 ? 689 VAL M N     1 
ATOM   5284 C CA    . VAL A 1 684 ? 126.760 196.823 152.081 1.00 161.73 ? 689 VAL M CA    1 
ATOM   5285 C C     . VAL A 1 684 ? 127.893 195.802 152.109 1.00 161.73 ? 689 VAL M C     1 
ATOM   5286 O O     . VAL A 1 684 ? 128.099 195.110 153.113 1.00 161.73 ? 689 VAL M O     1 
ATOM   5287 C CB    . VAL A 1 684 ? 125.560 196.310 151.268 1.00 161.73 ? 689 VAL M CB    1 
ATOM   5288 C CG1   . VAL A 1 684 ? 125.059 195.003 151.852 1.00 161.73 ? 689 VAL M CG1   1 
ATOM   5289 C CG2   . VAL A 1 684 ? 124.457 197.346 151.253 1.00 161.73 ? 689 VAL M CG2   1 
ATOM   5290 N N     . MET A 1 685 ? 128.639 195.683 151.005 1.00 160.49 ? 690 MET M N     1 
ATOM   5291 C CA    . MET A 1 685 ? 129.760 194.743 150.985 1.00 160.49 ? 690 MET M CA    1 
ATOM   5292 C C     . MET A 1 685 ? 130.784 195.089 152.052 1.00 160.49 ? 690 MET M C     1 
ATOM   5293 O O     . MET A 1 685 ? 131.354 194.198 152.696 1.00 160.49 ? 690 MET M O     1 
ATOM   5294 C CB    . MET A 1 685 ? 130.458 194.736 149.631 1.00 160.49 ? 690 MET M CB    1 
ATOM   5295 C CG    . MET A 1 685 ? 129.606 194.572 148.420 1.00 160.49 ? 690 MET M CG    1 
ATOM   5296 S SD    . MET A 1 685 ? 130.754 194.421 147.046 1.00 160.49 ? 690 MET M SD    1 
ATOM   5297 C CE    . MET A 1 685 ? 130.727 196.077 146.372 1.00 160.49 ? 690 MET M CE    1 
ATOM   5298 N N     . HIS A 1 686 ? 131.068 196.380 152.213 1.00 151.73 ? 691 HIS M N     1 
ATOM   5299 C CA    . HIS A 1 686 ? 132.043 196.801 153.205 1.00 151.73 ? 691 HIS M CA    1 
ATOM   5300 C C     . HIS A 1 686 ? 131.609 196.365 154.592 1.00 151.73 ? 691 HIS M C     1 
ATOM   5301 O O     . HIS A 1 686 ? 132.403 195.805 155.357 1.00 151.73 ? 691 HIS M O     1 
ATOM   5302 C CB    . HIS A 1 686 ? 132.224 198.314 153.137 1.00 151.73 ? 691 HIS M CB    1 
ATOM   5303 C CG    . HIS A 1 686 ? 133.553 198.783 153.634 1.00 151.73 ? 691 HIS M CG    1 
ATOM   5304 N ND1   . HIS A 1 686 ? 134.718 198.607 152.920 1.00 151.73 ? 691 HIS M ND1   1 
ATOM   5305 C CD2   . HIS A 1 686 ? 133.903 199.421 154.774 1.00 151.73 ? 691 HIS M CD2   1 
ATOM   5306 C CE1   . HIS A 1 686 ? 135.729 199.119 153.598 1.00 151.73 ? 691 HIS M CE1   1 
ATOM   5307 N NE2   . HIS A 1 686 ? 135.260 199.622 154.726 1.00 151.73 ? 691 HIS M NE2   1 
ATOM   5308 N N     . GLN A 1 687 ? 130.341 196.600 154.929 1.00 152.40 ? 692 GLN M N     1 
ATOM   5309 C CA    . GLN A 1 687 ? 129.856 196.194 156.242 1.00 152.40 ? 692 GLN M CA    1 
ATOM   5310 C C     . GLN A 1 687 ? 129.918 194.682 156.403 1.00 152.40 ? 692 GLN M C     1 
ATOM   5311 O O     . GLN A 1 687 ? 130.325 194.184 157.454 1.00 152.40 ? 692 GLN M O     1 
ATOM   5312 C CB    . GLN A 1 687 ? 128.435 196.701 156.471 1.00 152.40 ? 692 GLN M CB    1 
ATOM   5313 C CG    . GLN A 1 687 ? 128.280 198.201 156.323 1.00 152.40 ? 692 GLN M CG    1 
ATOM   5314 C CD    . GLN A 1 687 ? 129.555 198.953 156.631 1.00 152.40 ? 692 GLN M CD    1 
ATOM   5315 O OE1   . GLN A 1 687 ? 129.987 199.023 157.780 1.00 152.40 ? 692 GLN M OE1   1 
ATOM   5316 N NE2   . GLN A 1 687 ? 130.172 199.516 155.600 1.00 152.40 ? 692 GLN M NE2   1 
ATOM   5317 N N     . LEU A 1 688 ? 129.551 193.936 155.360 1.00 151.56 ? 693 LEU M N     1 
ATOM   5318 C CA    . LEU A 1 688 ? 129.551 192.478 155.457 1.00 151.56 ? 693 LEU M CA    1 
ATOM   5319 C C     . LEU A 1 688 ? 130.955 191.943 155.708 1.00 151.56 ? 693 LEU M C     1 
ATOM   5320 O O     . LEU A 1 688 ? 131.171 191.125 156.614 1.00 151.56 ? 693 LEU M O     1 
ATOM   5321 C CB    . LEU A 1 688 ? 128.961 191.871 154.184 1.00 151.56 ? 693 LEU M CB    1 
ATOM   5322 C CG    . LEU A 1 688 ? 127.459 191.562 154.141 1.00 151.56 ? 693 LEU M CG    1 
ATOM   5323 C CD1   . LEU A 1 688 ? 127.129 190.424 155.077 1.00 151.56 ? 693 LEU M CD1   1 
ATOM   5324 C CD2   . LEU A 1 688 ? 126.613 192.772 154.483 1.00 151.56 ? 693 LEU M CD2   1 
ATOM   5325 N N     . ARG A 1 689 ? 131.929 192.415 154.926 1.00 147.05 ? 694 ARG M N     1 
ATOM   5326 C CA    . ARG A 1 689 ? 133.306 191.959 155.098 1.00 147.05 ? 694 ARG M CA    1 
ATOM   5327 C C     . ARG A 1 689 ? 133.854 192.366 156.458 1.00 147.05 ? 694 ARG M C     1 
ATOM   5328 O O     . ARG A 1 689 ? 134.333 191.522 157.221 1.00 147.05 ? 694 ARG M O     1 
ATOM   5329 C CB    . ARG A 1 689 ? 134.196 192.515 153.987 1.00 147.05 ? 694 ARG M CB    1 
ATOM   5330 C CG    . ARG A 1 689 ? 133.853 192.025 152.602 1.00 147.05 ? 694 ARG M CG    1 
ATOM   5331 C CD    . ARG A 1 689 ? 134.797 192.608 151.577 1.00 147.05 ? 694 ARG M CD    1 
ATOM   5332 N NE    . ARG A 1 689 ? 134.337 192.358 150.218 1.00 147.05 ? 694 ARG M NE    1 
ATOM   5333 C CZ    . ARG A 1 689 ? 134.995 192.740 149.131 1.00 147.05 ? 694 ARG M CZ    1 
ATOM   5334 N NH1   . ARG A 1 689 ? 136.146 193.387 149.247 1.00 147.05 ? 694 ARG M NH1   1 
ATOM   5335 N NH2   . ARG A 1 689 ? 134.505 192.476 147.929 1.00 147.05 ? 694 ARG M NH2   1 
ATOM   5336 N N     . CYS A 1 690 ? 133.784 193.658 156.785 1.00 142.28 ? 695 CYS M N     1 
ATOM   5337 C CA    . CYS A 1 690 ? 134.341 194.134 158.041 1.00 142.28 ? 695 CYS M CA    1 
ATOM   5338 C C     . CYS A 1 690 ? 133.601 193.584 159.249 1.00 142.28 ? 695 CYS M C     1 
ATOM   5339 O O     . CYS A 1 690 ? 134.126 193.650 160.363 1.00 142.28 ? 695 CYS M O     1 
ATOM   5340 C CB    . CYS A 1 690 ? 134.325 195.661 158.072 1.00 142.28 ? 695 CYS M CB    1 
ATOM   5341 S SG    . CYS A 1 690 ? 135.286 196.428 156.752 1.00 142.28 ? 695 CYS M SG    1 
ATOM   5342 N N     . ASN A 1 691 ? 132.404 193.040 159.059 1.00 145.72 ? 696 ASN M N     1 
ATOM   5343 C CA    . ASN A 1 691 ? 131.627 192.514 160.166 1.00 145.72 ? 696 ASN M CA    1 
ATOM   5344 C C     . ASN A 1 691 ? 131.861 191.029 160.387 1.00 145.72 ? 696 ASN M C     1 
ATOM   5345 O O     . ASN A 1 691 ? 131.808 190.559 161.528 1.00 145.72 ? 696 ASN M O     1 
ATOM   5346 C CB    . ASN A 1 691 ? 130.145 192.776 159.909 1.00 145.72 ? 696 ASN M CB    1 
ATOM   5347 C CG    . ASN A 1 691 ? 129.338 192.801 161.172 1.00 145.72 ? 696 ASN M CG    1 
ATOM   5348 O OD1   . ASN A 1 691 ? 129.882 192.680 162.266 1.00 145.72 ? 696 ASN M OD1   1 
ATOM   5349 N ND2   . ASN A 1 691 ? 128.031 192.977 161.035 1.00 145.72 ? 696 ASN M ND2   1 
ATOM   5350 N N     . GLY A 1 692 ? 132.109 190.275 159.323 1.00 148.41 ? 697 GLY M N     1 
ATOM   5351 C CA    . GLY A 1 692 ? 132.381 188.864 159.480 1.00 148.41 ? 697 GLY M CA    1 
ATOM   5352 C C     . GLY A 1 692 ? 131.189 187.958 159.291 1.00 148.41 ? 697 GLY M C     1 
ATOM   5353 O O     . GLY A 1 692 ? 131.292 186.757 159.569 1.00 148.41 ? 697 GLY M O     1 
ATOM   5354 N N     . VAL A 1 693 ? 130.058 188.492 158.831 1.00 151.66 ? 698 VAL M N     1 
ATOM   5355 C CA    . VAL A 1 693 ? 128.967 187.631 158.391 1.00 151.66 ? 698 VAL M CA    1 
ATOM   5356 C C     . VAL A 1 693 ? 129.437 186.739 157.252 1.00 151.66 ? 698 VAL M C     1 
ATOM   5357 O O     . VAL A 1 693 ? 129.099 185.549 157.186 1.00 151.66 ? 698 VAL M O     1 
ATOM   5358 C CB    . VAL A 1 693 ? 127.757 188.487 157.982 1.00 151.66 ? 698 VAL M CB    1 
ATOM   5359 C CG1   . VAL A 1 693 ? 126.682 187.623 157.345 1.00 151.66 ? 698 VAL M CG1   1 
ATOM   5360 C CG2   . VAL A 1 693 ? 127.213 189.240 159.184 1.00 151.66 ? 698 VAL M CG2   1 
ATOM   5361 N N     . LEU A 1 694 ? 130.231 187.303 156.342 1.00 152.37 ? 699 LEU M N     1 
ATOM   5362 C CA    . LEU A 1 694 ? 130.788 186.514 155.253 1.00 152.37 ? 699 LEU M CA    1 
ATOM   5363 C C     . LEU A 1 694 ? 131.723 185.438 155.784 1.00 152.37 ? 699 LEU M C     1 
ATOM   5364 O O     . LEU A 1 694 ? 131.762 184.322 155.258 1.00 152.37 ? 699 LEU M O     1 
ATOM   5365 C CB    . LEU A 1 694 ? 131.514 187.429 154.271 1.00 152.37 ? 699 LEU M CB    1 
ATOM   5366 C CG    . LEU A 1 694 ? 130.717 188.651 153.814 1.00 152.37 ? 699 LEU M CG    1 
ATOM   5367 C CD1   . LEU A 1 694 ? 131.513 189.438 152.809 1.00 152.37 ? 699 LEU M CD1   1 
ATOM   5368 C CD2   . LEU A 1 694 ? 129.394 188.232 153.213 1.00 152.37 ? 699 LEU M CD2   1 
ATOM   5369 N N     . GLU A 1 695 ? 132.467 185.742 156.845 1.00 150.90 ? 700 GLU M N     1 
ATOM   5370 C CA    . GLU A 1 695 ? 133.327 184.724 157.433 1.00 150.90 ? 700 GLU M CA    1 
ATOM   5371 C C     . GLU A 1 695 ? 132.505 183.628 158.096 1.00 150.90 ? 700 GLU M C     1 
ATOM   5372 O O     . GLU A 1 695 ? 132.876 182.452 158.046 1.00 150.90 ? 700 GLU M O     1 
ATOM   5373 C CB    . GLU A 1 695 ? 134.294 185.362 158.425 1.00 150.90 ? 700 GLU M CB    1 
ATOM   5374 C CG    . GLU A 1 695 ? 135.353 186.204 157.746 1.00 150.90 ? 700 GLU M CG    1 
ATOM   5375 C CD    . GLU A 1 695 ? 135.987 185.488 156.564 1.00 150.90 ? 700 GLU M CD    1 
ATOM   5376 O OE1   . GLU A 1 695 ? 136.390 184.318 156.722 1.00 150.90 ? 700 GLU M OE1   1 
ATOM   5377 O OE2   . GLU A 1 695 ? 136.072 186.090 155.474 1.00 150.90 ? 700 GLU M OE2   1 
ATOM   5378 N N     . GLY A 1 696 ? 131.382 183.992 158.711 1.00 153.26 ? 701 GLY M N     1 
ATOM   5379 C CA    . GLY A 1 696 ? 130.497 182.976 159.260 1.00 153.26 ? 701 GLY M CA    1 
ATOM   5380 C C     . GLY A 1 696 ? 129.962 182.043 158.190 1.00 153.26 ? 701 GLY M C     1 
ATOM   5381 O O     . GLY A 1 696 ? 130.040 180.815 158.315 1.00 153.26 ? 701 GLY M O     1 
ATOM   5382 N N     . ILE A 1 697 ? 129.425 182.616 157.108 1.00 155.91 ? 702 ILE M N     1 
ATOM   5383 C CA    . ILE A 1 697 ? 128.905 181.774 156.034 1.00 155.91 ? 702 ILE M CA    1 
ATOM   5384 C C     . ILE A 1 697 ? 130.032 180.969 155.405 1.00 155.91 ? 702 ILE M C     1 
ATOM   5385 O O     . ILE A 1 697 ? 129.810 179.862 154.904 1.00 155.91 ? 702 ILE M O     1 
ATOM   5386 C CB    . ILE A 1 697 ? 128.153 182.606 154.973 1.00 155.91 ? 702 ILE M CB    1 
ATOM   5387 C CG1   . ILE A 1 697 ? 129.125 183.450 154.150 1.00 155.91 ? 702 ILE M CG1   1 
ATOM   5388 C CG2   . ILE A 1 697 ? 127.097 183.485 155.627 1.00 155.91 ? 702 ILE M CG2   1 
ATOM   5389 C CD1   . ILE A 1 697 ? 128.660 183.749 152.753 1.00 155.91 ? 702 ILE M CD1   1 
ATOM   5390 N N     . ARG A 1 698 ? 131.261 181.482 155.448 1.00 155.60 ? 703 ARG M N     1 
ATOM   5391 C CA    . ARG A 1 698 ? 132.368 180.733 154.872 1.00 155.60 ? 703 ARG M CA    1 
ATOM   5392 C C     . ARG A 1 698 ? 132.761 179.556 155.756 1.00 155.60 ? 703 ARG M C     1 
ATOM   5393 O O     . ARG A 1 698 ? 133.076 178.476 155.248 1.00 155.60 ? 703 ARG M O     1 
ATOM   5394 C CB    . ARG A 1 698 ? 133.554 181.662 154.636 1.00 155.60 ? 703 ARG M CB    1 
ATOM   5395 C CG    . ARG A 1 698 ? 134.667 181.034 153.830 1.00 155.60 ? 703 ARG M CG    1 
ATOM   5396 C CD    . ARG A 1 698 ? 135.915 181.891 153.871 1.00 155.60 ? 703 ARG M CD    1 
ATOM   5397 N NE    . ARG A 1 698 ? 136.285 182.250 155.234 1.00 155.60 ? 703 ARG M NE    1 
ATOM   5398 C CZ    . ARG A 1 698 ? 136.886 181.424 156.081 1.00 155.60 ? 703 ARG M CZ    1 
ATOM   5399 N NH1   . ARG A 1 698 ? 137.175 180.187 155.707 1.00 155.60 ? 703 ARG M NH1   1 
ATOM   5400 N NH2   . ARG A 1 698 ? 137.192 181.832 157.303 1.00 155.60 ? 703 ARG M NH2   1 
ATOM   5401 N N     . ILE A 1 699 ? 132.747 179.740 157.076 1.00 155.77 ? 704 ILE M N     1 
ATOM   5402 C CA    . ILE A 1 699 ? 132.950 178.602 157.969 1.00 155.77 ? 704 ILE M CA    1 
ATOM   5403 C C     . ILE A 1 699 ? 131.864 177.562 157.748 1.00 155.77 ? 704 ILE M C     1 
ATOM   5404 O O     . ILE A 1 699 ? 132.124 176.353 157.791 1.00 155.77 ? 704 ILE M O     1 
ATOM   5405 C CB    . ILE A 1 699 ? 133.007 179.055 159.439 1.00 155.77 ? 704 ILE M CB    1 
ATOM   5406 C CG1   . ILE A 1 699 ? 133.988 180.211 159.618 1.00 155.77 ? 704 ILE M CG1   1 
ATOM   5407 C CG2   . ILE A 1 699 ? 133.402 177.895 160.330 1.00 155.77 ? 704 ILE M CG2   1 
ATOM   5408 C CD1   . ILE A 1 699 ? 135.386 179.894 159.163 1.00 155.77 ? 704 ILE M CD1   1 
ATOM   5409 N N     . CYS A 1 700 ? 130.633 178.013 157.493 1.00 160.68 ? 705 CYS M N     1 
ATOM   5410 C CA    . CYS A 1 700 ? 129.568 177.068 157.163 1.00 160.68 ? 705 CYS M CA    1 
ATOM   5411 C C     . CYS A 1 700 ? 129.852 176.342 155.851 1.00 160.68 ? 705 CYS M C     1 
ATOM   5412 O O     . CYS A 1 700 ? 129.597 175.137 155.734 1.00 160.68 ? 705 CYS M O     1 
ATOM   5413 C CB    . CYS A 1 700 ? 128.222 177.787 157.087 1.00 160.68 ? 705 CYS M CB    1 
ATOM   5414 S SG    . CYS A 1 700 ? 127.788 178.744 158.550 1.00 160.68 ? 705 CYS M SG    1 
ATOM   5415 N N     . ARG A 1 701 ? 130.400 177.053 154.863 1.00 161.69 ? 706 ARG M N     1 
ATOM   5416 C CA    . ARG A 1 701 ? 130.541 176.512 153.515 1.00 161.69 ? 706 ARG M CA    1 
ATOM   5417 C C     . ARG A 1 701 ? 131.480 175.313 153.443 1.00 161.69 ? 706 ARG M C     1 
ATOM   5418 O O     . ARG A 1 701 ? 131.584 174.688 152.384 1.00 161.69 ? 706 ARG M O     1 
ATOM   5419 C CB    . ARG A 1 701 ? 131.029 177.607 152.568 1.00 161.69 ? 706 ARG M CB    1 
ATOM   5420 C CG    . ARG A 1 701 ? 130.611 177.409 151.127 1.00 161.69 ? 706 ARG M CG    1 
ATOM   5421 C CD    . ARG A 1 701 ? 131.162 178.500 150.235 1.00 161.69 ? 706 ARG M CD    1 
ATOM   5422 N NE    . ARG A 1 701 ? 130.467 178.559 148.952 1.00 161.69 ? 706 ARG M NE    1 
ATOM   5423 C CZ    . ARG A 1 701 ? 130.765 177.801 147.903 1.00 161.69 ? 706 ARG M CZ    1 
ATOM   5424 N NH1   . ARG A 1 701 ? 131.745 176.913 147.982 1.00 161.69 ? 706 ARG M NH1   1 
ATOM   5425 N NH2   . ARG A 1 701 ? 130.081 177.927 146.776 1.00 161.69 ? 706 ARG M NH2   1 
ATOM   5426 N N     . LYS A 1 702 ? 132.182 174.987 154.526 1.00 163.73 ? 707 LYS M N     1 
ATOM   5427 C CA    . LYS A 1 702 ? 133.056 173.823 154.510 1.00 163.73 ? 707 LYS M CA    1 
ATOM   5428 C C     . LYS A 1 702 ? 132.353 172.546 154.953 1.00 163.73 ? 707 LYS M C     1 
ATOM   5429 O O     . LYS A 1 702 ? 132.847 171.453 154.658 1.00 163.73 ? 707 LYS M O     1 
ATOM   5430 C CB    . LYS A 1 702 ? 134.288 174.080 155.378 1.00 163.73 ? 707 LYS M CB    1 
ATOM   5431 C CG    . LYS A 1 702 ? 134.826 175.494 155.254 1.00 163.73 ? 707 LYS M CG    1 
ATOM   5432 C CD    . LYS A 1 702 ? 135.381 175.750 153.858 1.00 163.73 ? 707 LYS M CD    1 
ATOM   5433 C CE    . LYS A 1 702 ? 135.286 177.221 153.476 1.00 163.73 ? 707 LYS M CE    1 
ATOM   5434 N NZ    . LYS A 1 702 ? 135.267 177.438 152.002 1.00 163.73 ? 707 LYS M NZ    1 
ATOM   5435 N N     . GLY A 1 703 ? 131.222 172.654 155.645 1.00 172.72 ? 708 GLY M N     1 
ATOM   5436 C CA    . GLY A 1 703 ? 130.465 171.480 156.037 1.00 172.72 ? 708 GLY M CA    1 
ATOM   5437 C C     . GLY A 1 703 ? 129.269 171.234 155.141 1.00 172.72 ? 708 GLY M C     1 
ATOM   5438 O O     . GLY A 1 703 ? 129.390 171.265 153.914 1.00 172.72 ? 708 GLY M O     1 
ATOM   5439 N N     . PHE A 1 704 ? 128.108 170.978 155.736 1.00 179.49 ? 709 PHE M N     1 
ATOM   5440 C CA    . PHE A 1 704 ? 126.852 170.885 154.992 1.00 179.49 ? 709 PHE M CA    1 
ATOM   5441 C C     . PHE A 1 704 ? 125.913 171.954 155.524 1.00 179.49 ? 709 PHE M C     1 
ATOM   5442 O O     . PHE A 1 704 ? 125.317 171.783 156.603 1.00 179.49 ? 709 PHE M O     1 
ATOM   5443 C CB    . PHE A 1 704 ? 126.223 169.499 155.111 1.00 179.49 ? 709 PHE M CB    1 
ATOM   5444 C CG    . PHE A 1 704 ? 127.058 168.403 154.510 1.00 179.49 ? 709 PHE M CG    1 
ATOM   5445 C CD1   . PHE A 1 704 ? 127.008 168.143 153.150 1.00 179.49 ? 709 PHE M CD1   1 
ATOM   5446 C CD2   . PHE A 1 704 ? 127.889 167.632 155.304 1.00 179.49 ? 709 PHE M CD2   1 
ATOM   5447 C CE1   . PHE A 1 704 ? 127.775 167.139 152.596 1.00 179.49 ? 709 PHE M CE1   1 
ATOM   5448 C CE2   . PHE A 1 704 ? 128.654 166.627 154.755 1.00 179.49 ? 709 PHE M CE2   1 
ATOM   5449 C CZ    . PHE A 1 704 ? 128.598 166.380 153.400 1.00 179.49 ? 709 PHE M CZ    1 
ATOM   5450 N N     . PRO A 1 705 ? 125.766 173.070 154.830 1.00 177.08 ? 710 PRO M N     1 
ATOM   5451 C CA    . PRO A 1 705 ? 124.947 174.165 155.357 1.00 177.08 ? 710 PRO M CA    1 
ATOM   5452 C C     . PRO A 1 705 ? 123.459 173.955 155.127 1.00 177.08 ? 710 PRO M C     1 
ATOM   5453 O O     . PRO A 1 705 ? 122.636 174.395 155.937 1.00 177.08 ? 710 PRO M O     1 
ATOM   5454 C CB    . PRO A 1 705 ? 125.470 175.380 154.588 1.00 177.08 ? 710 PRO M CB    1 
ATOM   5455 C CG    . PRO A 1 705 ? 125.923 174.811 153.286 1.00 177.08 ? 710 PRO M CG    1 
ATOM   5456 C CD    . PRO A 1 705 ? 126.427 173.426 153.563 1.00 177.08 ? 710 PRO M CD    1 
ATOM   5457 N N     . ASN A 1 706 ? 123.099 173.286 154.033 1.00 178.72 ? 711 ASN M N     1 
ATOM   5458 C CA    . ASN A 1 706 ? 121.705 172.976 153.739 1.00 178.72 ? 711 ASN M CA    1 
ATOM   5459 C C     . ASN A 1 706 ? 121.334 171.714 154.509 1.00 178.72 ? 711 ASN M C     1 
ATOM   5460 O O     . ASN A 1 706 ? 121.802 170.618 154.186 1.00 178.72 ? 711 ASN M O     1 
ATOM   5461 C CB    . ASN A 1 706 ? 121.486 172.808 152.238 1.00 178.72 ? 711 ASN M CB    1 
ATOM   5462 C CG    . ASN A 1 706 ? 121.801 174.075 151.460 1.00 178.72 ? 711 ASN M CG    1 
ATOM   5463 O OD1   . ASN A 1 706 ? 122.571 174.055 150.500 1.00 178.72 ? 711 ASN M OD1   1 
ATOM   5464 N ND2   . ASN A 1 706 ? 121.209 175.187 151.879 1.00 178.72 ? 711 ASN M ND2   1 
ATOM   5465 N N     . ARG A 1 707 ? 120.503 171.875 155.534 1.00 178.41 ? 712 ARG M N     1 
ATOM   5466 C CA    . ARG A 1 707 ? 120.192 170.812 156.480 1.00 178.41 ? 712 ARG M CA    1 
ATOM   5467 C C     . ARG A 1 707 ? 118.682 170.733 156.648 1.00 178.41 ? 712 ARG M C     1 
ATOM   5468 O O     . ARG A 1 707 ? 118.077 171.615 157.266 1.00 178.41 ? 712 ARG M O     1 
ATOM   5469 C CB    . ARG A 1 707 ? 120.881 171.071 157.824 1.00 178.41 ? 712 ARG M CB    1 
ATOM   5470 C CG    . ARG A 1 707 ? 122.356 171.415 157.685 1.00 178.41 ? 712 ARG M CG    1 
ATOM   5471 C CD    . ARG A 1 707 ? 123.057 171.557 159.025 1.00 178.41 ? 712 ARG M CD    1 
ATOM   5472 N NE    . ARG A 1 707 ? 124.506 171.420 158.881 1.00 178.41 ? 712 ARG M NE    1 
ATOM   5473 C CZ    . ARG A 1 707 ? 125.366 171.408 159.894 1.00 178.41 ? 712 ARG M CZ    1 
ATOM   5474 N NH1   . ARG A 1 707 ? 124.933 171.528 161.141 1.00 178.41 ? 712 ARG M NH1   1 
ATOM   5475 N NH2   . ARG A 1 707 ? 126.663 171.274 159.660 1.00 178.41 ? 712 ARG M NH2   1 
ATOM   5476 N N     . ILE A 1 708 ? 118.079 169.675 156.108 1.00 183.96 ? 713 ILE M N     1 
ATOM   5477 C CA    . ILE A 1 708 ? 116.630 169.534 156.080 1.00 183.96 ? 713 ILE M CA    1 
ATOM   5478 C C     . ILE A 1 708 ? 116.254 168.126 156.524 1.00 183.96 ? 713 ILE M C     1 
ATOM   5479 O O     . ILE A 1 708 ? 116.986 167.160 156.290 1.00 183.96 ? 713 ILE M O     1 
ATOM   5480 C CB    . ILE A 1 708 ? 116.059 169.845 154.677 1.00 183.96 ? 713 ILE M CB    1 
ATOM   5481 C CG1   . ILE A 1 708 ? 114.531 169.940 154.717 1.00 183.96 ? 713 ILE M CG1   1 
ATOM   5482 C CG2   . ILE A 1 708 ? 116.516 168.805 153.665 1.00 183.96 ? 713 ILE M CG2   1 
ATOM   5483 C CD1   . ILE A 1 708 ? 114.012 171.213 155.339 1.00 183.96 ? 713 ILE M CD1   1 
ATOM   5484 N N     . LEU A 1 709 ? 115.097 168.024 157.174 1.00 187.28 ? 714 LEU M N     1 
ATOM   5485 C CA    . LEU A 1 709 ? 114.576 166.763 157.677 1.00 187.28 ? 714 LEU M CA    1 
ATOM   5486 C C     . LEU A 1 709 ? 114.141 165.862 156.521 1.00 187.28 ? 714 LEU M C     1 
ATOM   5487 O O     . LEU A 1 709 ? 114.246 166.212 155.342 1.00 187.28 ? 714 LEU M O     1 
ATOM   5488 C CB    . LEU A 1 709 ? 113.421 167.023 158.643 1.00 187.28 ? 714 LEU M CB    1 
ATOM   5489 C CG    . LEU A 1 709 ? 112.046 167.461 158.115 1.00 187.28 ? 714 LEU M CG    1 
ATOM   5490 C CD1   . LEU A 1 709 ? 111.040 167.525 159.259 1.00 187.28 ? 714 LEU M CD1   1 
ATOM   5491 C CD2   . LEU A 1 709 ? 112.083 168.790 157.378 1.00 187.28 ? 714 LEU M CD2   1 
ATOM   5492 N N     . TYR A 1 710 ? 113.651 164.672 156.870 1.00 189.11 ? 715 TYR M N     1 
ATOM   5493 C CA    . TYR A 1 710 ? 113.240 163.690 155.873 1.00 189.11 ? 715 TYR M CA    1 
ATOM   5494 C C     . TYR A 1 710 ? 111.803 163.868 155.411 1.00 189.11 ? 715 TYR M C     1 
ATOM   5495 O O     . TYR A 1 710 ? 111.498 163.577 154.249 1.00 189.11 ? 715 TYR M O     1 
ATOM   5496 C CB    . TYR A 1 710 ? 113.402 162.274 156.429 1.00 189.11 ? 715 TYR M CB    1 
ATOM   5497 C CG    . TYR A 1 710 ? 114.830 161.802 156.498 1.00 189.11 ? 715 TYR M CG    1 
ATOM   5498 C CD1   . TYR A 1 710 ? 115.640 162.147 157.569 1.00 189.11 ? 715 TYR M CD1   1 
ATOM   5499 C CD2   . TYR A 1 710 ? 115.368 161.006 155.496 1.00 189.11 ? 715 TYR M CD2   1 
ATOM   5500 C CE1   . TYR A 1 710 ? 116.945 161.719 157.638 1.00 189.11 ? 715 TYR M CE1   1 
ATOM   5501 C CE2   . TYR A 1 710 ? 116.673 160.570 155.557 1.00 189.11 ? 715 TYR M CE2   1 
ATOM   5502 C CZ    . TYR A 1 710 ? 117.459 160.929 156.631 1.00 189.11 ? 715 TYR M CZ    1 
ATOM   5503 O OH    . TYR A 1 710 ? 118.765 160.498 156.700 1.00 189.11 ? 715 TYR M OH    1 
ATOM   5504 N N     . GLY A 1 711 ? 110.913 164.331 156.291 1.00 191.65 ? 716 GLY M N     1 
ATOM   5505 C CA    . GLY A 1 711 ? 109.502 164.391 155.938 1.00 191.65 ? 716 GLY M CA    1 
ATOM   5506 C C     . GLY A 1 711 ? 109.214 165.397 154.840 1.00 191.65 ? 716 GLY M C     1 
ATOM   5507 O O     . GLY A 1 711 ? 108.594 165.068 153.824 1.00 191.65 ? 716 GLY M O     1 
ATOM   5508 N N     . ASP A 1 712 ? 109.656 166.639 155.032 1.00 192.42 ? 717 ASP M N     1 
ATOM   5509 C CA    . ASP A 1 712 ? 109.456 167.654 154.005 1.00 192.42 ? 717 ASP M CA    1 
ATOM   5510 C C     . ASP A 1 712 ? 110.272 167.325 152.760 1.00 192.42 ? 717 ASP M C     1 
ATOM   5511 O O     . ASP A 1 712 ? 109.853 167.618 151.633 1.00 192.42 ? 717 ASP M O     1 
ATOM   5512 C CB    . ASP A 1 712 ? 109.823 169.027 154.567 1.00 192.42 ? 717 ASP M CB    1 
ATOM   5513 C CG    . ASP A 1 712 ? 109.249 170.161 153.759 1.00 192.42 ? 717 ASP M CG    1 
ATOM   5514 O OD1   . ASP A 1 712 ? 108.551 169.889 152.760 1.00 192.42 ? 717 ASP M OD1   1 
ATOM   5515 O OD2   . ASP A 1 712 ? 109.496 171.329 154.126 1.00 192.42 ? 717 ASP M OD2   1 
ATOM   5516 N N     . PHE A 1 713 ? 111.439 166.701 152.950 1.00 192.70 ? 718 PHE M N     1 
ATOM   5517 C CA    . PHE A 1 713 ? 112.211 166.180 151.825 1.00 192.70 ? 718 PHE M CA    1 
ATOM   5518 C C     . PHE A 1 713 ? 111.359 165.265 150.958 1.00 192.70 ? 718 PHE M C     1 
ATOM   5519 O O     . PHE A 1 713 ? 111.320 165.409 149.729 1.00 192.70 ? 718 PHE M O     1 
ATOM   5520 C CB    . PHE A 1 713 ? 113.442 165.438 152.346 1.00 192.70 ? 718 PHE M CB    1 
ATOM   5521 C CG    . PHE A 1 713 ? 114.068 164.511 151.345 1.00 192.70 ? 718 PHE M CG    1 
ATOM   5522 C CD1   . PHE A 1 713 ? 114.873 165.000 150.333 1.00 192.70 ? 718 PHE M CD1   1 
ATOM   5523 C CD2   . PHE A 1 713 ? 113.862 163.141 151.427 1.00 192.70 ? 718 PHE M CD2   1 
ATOM   5524 C CE1   . PHE A 1 713 ? 115.454 164.143 149.417 1.00 192.70 ? 718 PHE M CE1   1 
ATOM   5525 C CE2   . PHE A 1 713 ? 114.441 162.279 150.511 1.00 192.70 ? 718 PHE M CE2   1 
ATOM   5526 C CZ    . PHE A 1 713 ? 115.237 162.782 149.506 1.00 192.70 ? 718 PHE M CZ    1 
ATOM   5527 N N     . ARG A 1 714 ? 110.661 164.319 151.586 1.00 192.48 ? 719 ARG M N     1 
ATOM   5528 C CA    . ARG A 1 714 ? 109.758 163.444 150.849 1.00 192.48 ? 719 ARG M CA    1 
ATOM   5529 C C     . ARG A 1 714 ? 108.647 164.248 150.187 1.00 192.48 ? 719 ARG M C     1 
ATOM   5530 O O     . ARG A 1 714 ? 108.462 164.185 148.970 1.00 192.48 ? 719 ARG M O     1 
ATOM   5531 C CB    . ARG A 1 714 ? 109.181 162.379 151.786 1.00 192.48 ? 719 ARG M CB    1 
ATOM   5532 C CG    . ARG A 1 714 ? 110.191 161.342 152.256 1.00 192.48 ? 719 ARG M CG    1 
ATOM   5533 C CD    . ARG A 1 714 ? 109.749 160.682 153.556 1.00 192.48 ? 719 ARG M CD    1 
ATOM   5534 N NE    . ARG A 1 714 ? 108.591 159.807 153.387 1.00 192.48 ? 719 ARG M NE    1 
ATOM   5535 C CZ    . ARG A 1 714 ? 108.643 158.478 153.411 1.00 192.48 ? 719 ARG M CZ    1 
ATOM   5536 N NH1   . ARG A 1 714 ? 109.799 157.860 153.604 1.00 192.48 ? 719 ARG M NH1   1 
ATOM   5537 N NH2   . ARG A 1 714 ? 107.537 157.766 153.247 1.00 192.48 ? 719 ARG M NH2   1 
ATOM   5538 N N     . GLN A 1 715 ? 107.914 165.037 150.977 1.00 192.24 ? 720 GLN M N     1 
ATOM   5539 C CA    . GLN A 1 715 ? 106.773 165.779 150.441 1.00 192.24 ? 720 GLN M CA    1 
ATOM   5540 C C     . GLN A 1 715 ? 107.153 166.695 149.285 1.00 192.24 ? 720 GLN M C     1 
ATOM   5541 O O     . GLN A 1 715 ? 106.274 167.093 148.514 1.00 192.24 ? 720 GLN M O     1 
ATOM   5542 C CB    . GLN A 1 715 ? 106.097 166.614 151.532 1.00 192.24 ? 720 GLN M CB    1 
ATOM   5543 C CG    . GLN A 1 715 ? 105.792 165.869 152.818 1.00 192.24 ? 720 GLN M CG    1 
ATOM   5544 C CD    . GLN A 1 715 ? 104.761 164.775 152.640 1.00 192.24 ? 720 GLN M CD    1 
ATOM   5545 O OE1   . GLN A 1 715 ? 103.560 165.038 152.608 1.00 192.24 ? 720 GLN M OE1   1 
ATOM   5546 N NE2   . GLN A 1 715 ? 105.227 163.536 152.528 1.00 192.24 ? 720 GLN M NE2   1 
ATOM   5547 N N     . ARG A 1 716 ? 108.433 167.046 149.145 1.00 193.09 ? 721 ARG M N     1 
ATOM   5548 C CA    . ARG A 1 716 ? 108.854 167.907 148.051 1.00 193.09 ? 721 ARG M CA    1 
ATOM   5549 C C     . ARG A 1 716 ? 109.572 167.187 146.922 1.00 193.09 ? 721 ARG M C     1 
ATOM   5550 O O     . ARG A 1 716 ? 109.665 167.748 145.829 1.00 193.09 ? 721 ARG M O     1 
ATOM   5551 C CB    . ARG A 1 716 ? 109.770 169.026 148.566 1.00 193.09 ? 721 ARG M CB    1 
ATOM   5552 C CG    . ARG A 1 716 ? 109.088 169.998 149.501 1.00 193.09 ? 721 ARG M CG    1 
ATOM   5553 C CD    . ARG A 1 716 ? 110.095 170.919 150.146 1.00 193.09 ? 721 ARG M CD    1 
ATOM   5554 N NE    . ARG A 1 716 ? 109.478 171.767 151.158 1.00 193.09 ? 721 ARG M NE    1 
ATOM   5555 C CZ    . ARG A 1 716 ? 109.010 172.988 150.929 1.00 193.09 ? 721 ARG M CZ    1 
ATOM   5556 N NH1   . ARG A 1 716 ? 109.086 173.513 149.714 1.00 193.09 ? 721 ARG M NH1   1 
ATOM   5557 N NH2   . ARG A 1 716 ? 108.467 173.682 151.917 1.00 193.09 ? 721 ARG M NH2   1 
ATOM   5558 N N     . TYR A 1 717 ? 110.081 165.969 147.145 1.00 195.56 ? 722 TYR M N     1 
ATOM   5559 C CA    . TYR A 1 717 ? 110.870 165.303 146.114 1.00 195.56 ? 722 TYR M CA    1 
ATOM   5560 C C     . TYR A 1 717 ? 110.430 163.863 145.866 1.00 195.56 ? 722 TYR M C     1 
ATOM   5561 O O     . TYR A 1 717 ? 111.173 163.096 145.246 1.00 195.56 ? 722 TYR M O     1 
ATOM   5562 C CB    . TYR A 1 717 ? 112.355 165.334 146.478 1.00 195.56 ? 722 TYR M CB    1 
ATOM   5563 C CG    . TYR A 1 717 ? 112.931 166.725 146.614 1.00 195.56 ? 722 TYR M CG    1 
ATOM   5564 C CD1   . TYR A 1 717 ? 112.844 167.422 147.812 1.00 195.56 ? 722 TYR M CD1   1 
ATOM   5565 C CD2   . TYR A 1 717 ? 113.573 167.334 145.547 1.00 195.56 ? 722 TYR M CD2   1 
ATOM   5566 C CE1   . TYR A 1 717 ? 113.374 168.693 147.936 1.00 195.56 ? 722 TYR M CE1   1 
ATOM   5567 C CE2   . TYR A 1 717 ? 114.105 168.601 145.663 1.00 195.56 ? 722 TYR M CE2   1 
ATOM   5568 C CZ    . TYR A 1 717 ? 114.005 169.276 146.856 1.00 195.56 ? 722 TYR M CZ    1 
ATOM   5569 O OH    . TYR A 1 717 ? 114.536 170.539 146.963 1.00 195.56 ? 722 TYR M OH    1 
ATOM   5570 N N     . ARG A 1 718 ? 109.239 163.476 146.323 1.00 196.67 ? 723 ARG M N     1 
ATOM   5571 C CA    . ARG A 1 718 ? 108.785 162.106 146.124 1.00 196.67 ? 723 ARG M CA    1 
ATOM   5572 C C     . ARG A 1 718 ? 108.250 161.861 144.724 1.00 196.67 ? 723 ARG M C     1 
ATOM   5573 O O     . ARG A 1 718 ? 108.274 160.719 144.260 1.00 196.67 ? 723 ARG M O     1 
ATOM   5574 C CB    . ARG A 1 718 ? 107.708 161.757 147.155 1.00 196.67 ? 723 ARG M CB    1 
ATOM   5575 C CG    . ARG A 1 718 ? 107.667 160.288 147.559 1.00 196.67 ? 723 ARG M CG    1 
ATOM   5576 C CD    . ARG A 1 718 ? 107.263 160.149 149.020 1.00 196.67 ? 723 ARG M CD    1 
ATOM   5577 N NE    . ARG A 1 718 ? 106.712 158.834 149.329 1.00 196.67 ? 723 ARG M NE    1 
ATOM   5578 C CZ    . ARG A 1 718 ? 105.418 158.536 149.271 1.00 196.67 ? 723 ARG M CZ    1 
ATOM   5579 N NH1   . ARG A 1 718 ? 104.542 159.462 148.909 1.00 196.67 ? 723 ARG M NH1   1 
ATOM   5580 N NH2   . ARG A 1 718 ? 104.998 157.314 149.571 1.00 196.67 ? 723 ARG M NH2   1 
ATOM   5581 N N     . ILE A 1 719 ? 107.787 162.905 144.033 1.00 197.21 ? 724 ILE M N     1 
ATOM   5582 C CA    . ILE A 1 719 ? 107.249 162.723 142.692 1.00 197.21 ? 724 ILE M CA    1 
ATOM   5583 C C     . ILE A 1 719 ? 108.340 162.358 141.695 1.00 197.21 ? 724 ILE M C     1 
ATOM   5584 O O     . ILE A 1 719 ? 108.036 161.859 140.605 1.00 197.21 ? 724 ILE M O     1 
ATOM   5585 C CB    . ILE A 1 719 ? 106.487 163.987 142.257 1.00 197.21 ? 724 ILE M CB    1 
ATOM   5586 C CG1   . ILE A 1 719 ? 107.449 165.157 142.069 1.00 197.21 ? 724 ILE M CG1   1 
ATOM   5587 C CG2   . ILE A 1 719 ? 105.422 164.345 143.284 1.00 197.21 ? 724 ILE M CG2   1 
ATOM   5588 C CD1   . ILE A 1 719 ? 106.911 166.226 141.160 1.00 197.21 ? 724 ILE M CD1   1 
ATOM   5589 N N     . LEU A 1 720 ? 109.609 162.589 142.043 1.00 197.64 ? 725 LEU M N     1 
ATOM   5590 C CA    . LEU A 1 720 ? 110.709 162.131 141.200 1.00 197.64 ? 725 LEU M CA    1 
ATOM   5591 C C     . LEU A 1 720 ? 110.713 160.614 141.086 1.00 197.64 ? 725 LEU M C     1 
ATOM   5592 O O     . LEU A 1 720 ? 110.938 160.065 140.000 1.00 197.64 ? 725 LEU M O     1 
ATOM   5593 C CB    . LEU A 1 720 ? 112.040 162.617 141.768 1.00 197.64 ? 725 LEU M CB    1 
ATOM   5594 C CG    . LEU A 1 720 ? 112.299 164.120 141.759 1.00 197.64 ? 725 LEU M CG    1 
ATOM   5595 C CD1   . LEU A 1 720 ? 113.652 164.412 142.363 1.00 197.64 ? 725 LEU M CD1   1 
ATOM   5596 C CD2   . LEU A 1 720 ? 112.208 164.664 140.345 1.00 197.64 ? 725 LEU M CD2   1 
ATOM   5597 N N     . ASN A 1 721 ? 110.487 159.920 142.200 1.00 197.73 ? 726 ASN M N     1 
ATOM   5598 C CA    . ASN A 1 721 ? 110.374 158.462 142.233 1.00 197.73 ? 726 ASN M CA    1 
ATOM   5599 C C     . ASN A 1 721 ? 109.229 158.108 143.171 1.00 197.73 ? 726 ASN M C     1 
ATOM   5600 O O     . ASN A 1 721 ? 109.454 157.710 144.322 1.00 197.73 ? 726 ASN M O     1 
ATOM   5601 C CB    . ASN A 1 721 ? 111.682 157.814 142.679 1.00 197.73 ? 726 ASN M CB    1 
ATOM   5602 C CG    . ASN A 1 721 ? 112.719 157.787 141.581 1.00 197.73 ? 726 ASN M CG    1 
ATOM   5603 O OD1   . ASN A 1 721 ? 113.861 157.408 141.810 1.00 197.73 ? 726 ASN M OD1   1 
ATOM   5604 N ND2   . ASN A 1 721 ? 112.325 158.177 140.377 1.00 197.73 ? 726 ASN M ND2   1 
ATOM   5605 N N     . PRO A 1 722 ? 107.986 158.248 142.714 1.00 198.43 ? 727 PRO M N     1 
ATOM   5606 C CA    . PRO A 1 722 ? 106.847 158.049 143.617 1.00 198.43 ? 727 PRO M CA    1 
ATOM   5607 C C     . PRO A 1 722 ? 106.655 156.585 143.981 1.00 198.43 ? 727 PRO M C     1 
ATOM   5608 O O     . PRO A 1 722 ? 106.760 155.692 143.137 1.00 198.43 ? 727 PRO M O     1 
ATOM   5609 C CB    . PRO A 1 722 ? 105.660 158.592 142.814 1.00 198.43 ? 727 PRO M CB    1 
ATOM   5610 C CG    . PRO A 1 722 ? 106.074 158.453 141.390 1.00 198.43 ? 727 PRO M CG    1 
ATOM   5611 C CD    . PRO A 1 722 ? 107.564 158.643 141.359 1.00 198.43 ? 727 PRO M CD    1 
ATOM   5612 N N     . ALA A 1 723 ? 106.366 156.351 145.257 1.00 196.89 ? 728 ALA M N     1 
ATOM   5613 C CA    . ALA A 1 723 ? 106.141 155.006 145.770 1.00 196.89 ? 728 ALA M CA    1 
ATOM   5614 C C     . ALA A 1 723 ? 104.678 154.811 146.150 1.00 196.89 ? 728 ALA M C     1 
ATOM   5615 O O     . ALA A 1 723 ? 104.152 155.519 147.009 1.00 196.89 ? 728 ALA M O     1 
ATOM   5616 C CB    . ALA A 1 723 ? 107.043 154.734 146.968 1.00 196.89 ? 728 ALA M CB    1 
ATOM   5617 N N     . SER A 1 733 ? 111.880 154.746 156.548 1.00 190.91 ? 738 SER M N     1 
ATOM   5618 C CA    . SER A 1 733 ? 112.030 155.997 155.814 1.00 190.91 ? 738 SER M CA    1 
ATOM   5619 C C     . SER A 1 733 ? 113.419 156.086 155.202 1.00 190.91 ? 738 SER M C     1 
ATOM   5620 O O     . SER A 1 733 ? 113.669 156.896 154.312 1.00 190.91 ? 738 SER M O     1 
ATOM   5621 C CB    . SER A 1 733 ? 111.776 157.195 156.728 1.00 190.91 ? 738 SER M CB    1 
ATOM   5622 O OG    . SER A 1 733 ? 110.389 157.452 156.859 1.00 190.91 ? 738 SER M OG    1 
ATOM   5623 N N     . ARG A 1 734 ? 114.327 155.242 155.691 1.00 190.66 ? 739 ARG M N     1 
ATOM   5624 C CA    . ARG A 1 734 ? 115.673 155.221 155.136 1.00 190.66 ? 739 ARG M CA    1 
ATOM   5625 C C     . ARG A 1 734 ? 115.720 154.437 153.831 1.00 190.66 ? 739 ARG M C     1 
ATOM   5626 O O     . ARG A 1 734 ? 116.507 154.763 152.937 1.00 190.66 ? 739 ARG M O     1 
ATOM   5627 C CB    . ARG A 1 734 ? 116.660 154.636 156.146 1.00 190.66 ? 739 ARG M CB    1 
ATOM   5628 C CG    . ARG A 1 734 ? 116.451 155.078 157.589 1.00 190.66 ? 739 ARG M CG    1 
ATOM   5629 C CD    . ARG A 1 734 ? 116.366 156.587 157.736 1.00 190.66 ? 739 ARG M CD    1 
ATOM   5630 N NE    . ARG A 1 734 ? 116.366 156.982 159.140 1.00 190.66 ? 739 ARG M NE    1 
ATOM   5631 C CZ    . ARG A 1 734 ? 115.914 158.145 159.595 1.00 190.66 ? 739 ARG M CZ    1 
ATOM   5632 N NH1   . ARG A 1 734 ? 115.405 159.038 158.756 1.00 190.66 ? 739 ARG M NH1   1 
ATOM   5633 N NH2   . ARG A 1 734 ? 115.959 158.407 160.893 1.00 190.66 ? 739 ARG M NH2   1 
ATOM   5634 N N     . LYS A 1 735 ? 114.884 153.403 153.696 1.00 193.51 ? 740 LYS M N     1 
ATOM   5635 C CA    . LYS A 1 735 ? 114.948 152.569 152.499 1.00 193.51 ? 740 LYS M CA    1 
ATOM   5636 C C     . LYS A 1 735 ? 114.390 153.294 151.276 1.00 193.51 ? 740 LYS M C     1 
ATOM   5637 O O     . LYS A 1 735 ? 115.004 153.267 150.204 1.00 193.51 ? 740 LYS M O     1 
ATOM   5638 C CB    . LYS A 1 735 ? 114.222 151.239 152.734 1.00 193.51 ? 740 LYS M CB    1 
ATOM   5639 C CG    . LYS A 1 735 ? 112.731 151.341 153.024 1.00 193.51 ? 740 LYS M CG    1 
ATOM   5640 C CD    . LYS A 1 735 ? 111.964 150.230 152.329 1.00 193.51 ? 740 LYS M CD    1 
ATOM   5641 C CE    . LYS A 1 735 ? 110.517 150.181 152.781 1.00 193.51 ? 740 LYS M CE    1 
ATOM   5642 N NZ    . LYS A 1 735 ? 109.677 149.411 151.823 1.00 193.51 ? 740 LYS M NZ    1 
ATOM   5643 N N     . GLY A 1 736 ? 113.243 153.964 151.416 1.00 195.64 ? 741 GLY M N     1 
ATOM   5644 C CA    . GLY A 1 736 ? 112.697 154.708 150.291 1.00 195.64 ? 741 GLY M CA    1 
ATOM   5645 C C     . GLY A 1 736 ? 113.534 155.925 149.942 1.00 195.64 ? 741 GLY M C     1 
ATOM   5646 O O     . GLY A 1 736 ? 113.767 156.216 148.764 1.00 195.64 ? 741 GLY M O     1 
ATOM   5647 N N     . ALA A 1 737 ? 114.001 156.649 150.962 1.00 195.45 ? 742 ALA M N     1 
ATOM   5648 C CA    . ALA A 1 737 ? 114.917 157.757 150.724 1.00 195.45 ? 742 ALA M CA    1 
ATOM   5649 C C     . ALA A 1 737 ? 116.172 157.282 150.008 1.00 195.45 ? 742 ALA M C     1 
ATOM   5650 O O     . ALA A 1 737 ? 116.628 157.920 149.055 1.00 195.45 ? 742 ALA M O     1 
ATOM   5651 C CB    . ALA A 1 737 ? 115.278 158.432 152.047 1.00 195.45 ? 742 ALA M CB    1 
ATOM   5652 N N     . GLU A 1 738 ? 116.734 156.153 150.438 1.00 196.03 ? 743 GLU M N     1 
ATOM   5653 C CA    . GLU A 1 738 ? 117.952 155.647 149.820 1.00 196.03 ? 743 GLU M CA    1 
ATOM   5654 C C     . GLU A 1 738 ? 117.699 155.193 148.388 1.00 196.03 ? 743 GLU M C     1 
ATOM   5655 O O     . GLU A 1 738 ? 118.544 155.401 147.511 1.00 196.03 ? 743 GLU M O     1 
ATOM   5656 C CB    . GLU A 1 738 ? 118.521 154.501 150.656 1.00 196.03 ? 743 GLU M CB    1 
ATOM   5657 C CG    . GLU A 1 738 ? 119.778 153.871 150.079 1.00 196.03 ? 743 GLU M CG    1 
ATOM   5658 C CD    . GLU A 1 738 ? 120.891 154.871 149.867 1.00 196.03 ? 743 GLU M CD    1 
ATOM   5659 O OE1   . GLU A 1 738 ? 121.043 155.359 148.730 1.00 196.03 ? 743 GLU M OE1   1 
ATOM   5660 O OE2   . GLU A 1 738 ? 121.616 155.167 150.838 1.00 196.03 ? 743 GLU M OE2   1 
ATOM   5661 N N     . LYS A 1 739 ? 116.547 154.564 148.135 1.00 197.52 ? 744 LYS M N     1 
ATOM   5662 C CA    . LYS A 1 739 ? 116.202 154.169 146.773 1.00 197.52 ? 744 LYS M CA    1 
ATOM   5663 C C     . LYS A 1 739 ? 116.109 155.388 145.869 1.00 197.52 ? 744 LYS M C     1 
ATOM   5664 O O     . LYS A 1 739 ? 116.662 155.400 144.763 1.00 197.52 ? 744 LYS M O     1 
ATOM   5665 C CB    . LYS A 1 739 ? 114.880 153.398 146.774 1.00 197.52 ? 744 LYS M CB    1 
ATOM   5666 C CG    . LYS A 1 739 ? 114.323 153.076 145.391 1.00 197.52 ? 744 LYS M CG    1 
ATOM   5667 C CD    . LYS A 1 739 ? 112.794 153.064 145.392 1.00 197.52 ? 744 LYS M CD    1 
ATOM   5668 C CE    . LYS A 1 739 ? 112.214 154.433 145.041 1.00 197.52 ? 744 LYS M CE    1 
ATOM   5669 N NZ    . LYS A 1 739 ? 110.733 154.400 144.857 1.00 197.52 ? 744 LYS M NZ    1 
ATOM   5670 N N     . LEU A 1 740 ? 115.436 156.438 146.340 1.00 197.70 ? 745 LEU M N     1 
ATOM   5671 C CA    . LEU A 1 740 ? 115.339 157.668 145.565 1.00 197.70 ? 745 LEU M CA    1 
ATOM   5672 C C     . LEU A 1 740 ? 116.712 158.288 145.337 1.00 197.70 ? 745 LEU M C     1 
ATOM   5673 O O     . LEU A 1 740 ? 117.008 158.763 144.239 1.00 197.70 ? 745 LEU M O     1 
ATOM   5674 C CB    . LEU A 1 740 ? 114.409 158.647 146.282 1.00 197.70 ? 745 LEU M CB    1 
ATOM   5675 C CG    . LEU A 1 740 ? 114.270 160.067 145.742 1.00 197.70 ? 745 LEU M CG    1 
ATOM   5676 C CD1   . LEU A 1 740 ? 112.823 160.500 145.853 1.00 197.70 ? 745 LEU M CD1   1 
ATOM   5677 C CD2   . LEU A 1 740 ? 115.174 161.036 146.490 1.00 197.70 ? 745 LEU M CD2   1 
ATOM   5678 N N     . LEU A 1 741 ? 117.574 158.268 146.353 1.00 196.61 ? 746 LEU M N     1 
ATOM   5679 C CA    . LEU A 1 741 ? 118.891 158.882 146.212 1.00 196.61 ? 746 LEU M CA    1 
ATOM   5680 C C     . LEU A 1 741 ? 119.760 158.116 145.228 1.00 196.61 ? 746 LEU M C     1 
ATOM   5681 O O     . LEU A 1 741 ? 120.450 158.720 144.398 1.00 196.61 ? 746 LEU M O     1 
ATOM   5682 C CB    . LEU A 1 741 ? 119.580 158.971 147.572 1.00 196.61 ? 746 LEU M CB    1 
ATOM   5683 C CG    . LEU A 1 741 ? 119.503 160.299 148.322 1.00 196.61 ? 746 LEU M CG    1 
ATOM   5684 C CD1   . LEU A 1 741 ? 118.131 160.577 148.904 1.00 196.61 ? 746 LEU M CD1   1 
ATOM   5685 C CD2   . LEU A 1 741 ? 120.563 160.314 149.399 1.00 196.61 ? 746 LEU M CD2   1 
ATOM   5686 N N     . SER A 1 742 ? 119.750 156.786 145.308 1.00 197.18 ? 747 SER M N     1 
ATOM   5687 C CA    . SER A 1 742 ? 120.495 155.998 144.337 1.00 197.18 ? 747 SER M CA    1 
ATOM   5688 C C     . SER A 1 742 ? 119.936 156.182 142.936 1.00 197.18 ? 747 SER M C     1 
ATOM   5689 O O     . SER A 1 742 ? 120.695 156.162 141.962 1.00 197.18 ? 747 SER M O     1 
ATOM   5690 C CB    . SER A 1 742 ? 120.477 154.521 144.727 1.00 197.18 ? 747 SER M CB    1 
ATOM   5691 O OG    . SER A 1 742 ? 121.456 154.233 145.711 1.00 197.18 ? 747 SER M OG    1 
ATOM   5692 N N     . SER A 1 743 ? 118.622 156.368 142.814 1.00 199.19 ? 748 SER M N     1 
ATOM   5693 C CA    . SER A 1 743 ? 118.000 156.654 141.528 1.00 199.19 ? 748 SER M CA    1 
ATOM   5694 C C     . SER A 1 743 ? 117.978 158.143 141.190 1.00 199.19 ? 748 SER M C     1 
ATOM   5695 O O     . SER A 1 743 ? 117.302 158.535 140.234 1.00 199.19 ? 748 SER M O     1 
ATOM   5696 C CB    . SER A 1 743 ? 116.580 156.092 141.499 1.00 199.19 ? 748 SER M CB    1 
ATOM   5697 O OG    . SER A 1 743 ? 116.000 156.228 140.214 1.00 199.19 ? 748 SER M OG    1 
ATOM   5698 N N     . LEU A 1 744 ? 118.689 158.976 141.949 1.00 197.87 ? 749 LEU M N     1 
ATOM   5699 C CA    . LEU A 1 744 ? 118.916 160.372 141.598 1.00 197.87 ? 749 LEU M CA    1 
ATOM   5700 C C     . LEU A 1 744 ? 120.377 160.671 141.278 1.00 197.87 ? 749 LEU M C     1 
ATOM   5701 O O     . LEU A 1 744 ? 120.734 161.841 141.104 1.00 197.87 ? 749 LEU M O     1 
ATOM   5702 C CB    . LEU A 1 744 ? 118.415 161.294 142.715 1.00 197.87 ? 749 LEU M CB    1 
ATOM   5703 C CG    . LEU A 1 744 ? 117.030 161.950 142.572 1.00 197.87 ? 749 LEU M CG    1 
ATOM   5704 C CD1   . LEU A 1 744 ? 115.851 160.989 142.594 1.00 197.87 ? 749 LEU M CD1   1 
ATOM   5705 C CD2   . LEU A 1 744 ? 116.858 163.040 143.630 1.00 197.87 ? 749 LEU M CD2   1 
ATOM   5706 N N     . ASP A 1 745 ? 121.225 159.644 141.200 1.00 196.86 ? 750 ASP M N     1 
ATOM   5707 C CA    . ASP A 1 745 ? 122.632 159.796 140.815 1.00 196.86 ? 750 ASP M CA    1 
ATOM   5708 C C     . ASP A 1 745 ? 123.354 160.784 141.731 1.00 196.86 ? 750 ASP M C     1 
ATOM   5709 O O     . ASP A 1 745 ? 124.016 161.722 141.280 1.00 196.86 ? 750 ASP M O     1 
ATOM   5710 C CB    . ASP A 1 745 ? 122.766 160.205 139.345 1.00 196.86 ? 750 ASP M CB    1 
ATOM   5711 C CG    . ASP A 1 745 ? 124.211 160.211 138.870 1.00 196.86 ? 750 ASP M CG    1 
ATOM   5712 O OD1   . ASP A 1 745 ? 124.982 159.324 139.294 1.00 196.86 ? 750 ASP M OD1   1 
ATOM   5713 O OD2   . ASP A 1 745 ? 124.575 161.105 138.078 1.00 196.86 ? 750 ASP M OD2   1 
ATOM   5714 N N     . ILE A 1 746 ? 123.199 160.590 143.032 1.00 195.39 ? 751 ILE M N     1 
ATOM   5715 C CA    . ILE A 1 746 ? 123.887 161.402 144.025 1.00 195.39 ? 751 ILE M CA    1 
ATOM   5716 C C     . ILE A 1 746 ? 125.078 160.619 144.559 1.00 195.39 ? 751 ILE M C     1 
ATOM   5717 O O     . ILE A 1 746 ? 124.952 159.437 144.903 1.00 195.39 ? 751 ILE M O     1 
ATOM   5718 C CB    . ILE A 1 746 ? 122.932 161.804 145.158 1.00 195.39 ? 751 ILE M CB    1 
ATOM   5719 C CG1   . ILE A 1 746 ? 121.581 162.214 144.577 1.00 195.39 ? 751 ILE M CG1   1 
ATOM   5720 C CG2   . ILE A 1 746 ? 123.528 162.936 145.981 1.00 195.39 ? 751 ILE M CG2   1 
ATOM   5721 C CD1   . ILE A 1 746 ? 120.480 162.304 145.593 1.00 195.39 ? 751 ILE M CD1   1 
ATOM   5722 N N     . ASP A 1 747 ? 126.234 161.272 144.629 1.00 190.86 ? 752 ASP M N     1 
ATOM   5723 C CA    . ASP A 1 747 ? 127.420 160.606 145.144 1.00 190.86 ? 752 ASP M CA    1 
ATOM   5724 C C     . ASP A 1 747 ? 127.364 160.530 146.666 1.00 190.86 ? 752 ASP M C     1 
ATOM   5725 O O     . ASP A 1 747 ? 126.606 161.245 147.327 1.00 190.86 ? 752 ASP M O     1 
ATOM   5726 C CB    . ASP A 1 747 ? 128.689 161.330 144.697 1.00 190.86 ? 752 ASP M CB    1 
ATOM   5727 C CG    . ASP A 1 747 ? 128.898 161.265 143.200 1.00 190.86 ? 752 ASP M CG    1 
ATOM   5728 O OD1   . ASP A 1 747 ? 128.543 162.238 142.503 1.00 190.86 ? 752 ASP M OD1   1 
ATOM   5729 O OD2   . ASP A 1 747 ? 129.415 160.237 142.720 1.00 190.86 ? 752 ASP M OD2   1 
ATOM   5730 N N     . HIS A 1 748 ? 128.187 159.640 147.222 1.00 189.27 ? 753 HIS M N     1 
ATOM   5731 C CA    . HIS A 1 748 ? 128.156 159.408 148.661 1.00 189.27 ? 753 HIS M CA    1 
ATOM   5732 C C     . HIS A 1 748 ? 128.664 160.622 149.428 1.00 189.27 ? 753 HIS M C     1 
ATOM   5733 O O     . HIS A 1 748 ? 127.983 161.135 150.323 1.00 189.27 ? 753 HIS M O     1 
ATOM   5734 C CB    . HIS A 1 748 ? 128.983 158.169 149.006 1.00 189.27 ? 753 HIS M CB    1 
ATOM   5735 C CG    . HIS A 1 748 ? 128.953 157.810 150.459 1.00 189.27 ? 753 HIS M CG    1 
ATOM   5736 N ND1   . HIS A 1 748 ? 129.488 158.618 151.439 1.00 189.27 ? 753 HIS M ND1   1 
ATOM   5737 C CD2   . HIS A 1 748 ? 128.437 156.735 151.100 1.00 189.27 ? 753 HIS M CD2   1 
ATOM   5738 C CE1   . HIS A 1 748 ? 129.308 158.054 152.619 1.00 189.27 ? 753 HIS M CE1   1 
ATOM   5739 N NE2   . HIS A 1 748 ? 128.674 156.910 152.442 1.00 189.27 ? 753 HIS M NE2   1 
ATOM   5740 N N     . ASN A 1 749 ? 129.859 161.100 149.085 1.00 188.23 ? 754 ASN M N     1 
ATOM   5741 C CA    . ASN A 1 749 ? 130.486 162.187 149.821 1.00 188.23 ? 754 ASN M CA    1 
ATOM   5742 C C     . ASN A 1 749 ? 129.733 163.503 149.702 1.00 188.23 ? 754 ASN M C     1 
ATOM   5743 O O     . ASN A 1 749 ? 130.019 164.429 150.466 1.00 188.23 ? 754 ASN M O     1 
ATOM   5744 C CB    . ASN A 1 749 ? 131.921 162.366 149.332 1.00 188.23 ? 754 ASN M CB    1 
ATOM   5745 C CG    . ASN A 1 749 ? 132.011 162.443 147.822 1.00 188.23 ? 754 ASN M CG    1 
ATOM   5746 O OD1   . ASN A 1 749 ? 131.010 162.296 147.122 1.00 188.23 ? 754 ASN M OD1   1 
ATOM   5747 N ND2   . ASN A 1 749 ? 133.214 162.669 147.310 1.00 188.23 ? 754 ASN M ND2   1 
ATOM   5748 N N     . GLN A 1 750 ? 128.780 163.608 148.780 1.00 187.40 ? 755 GLN M N     1 
ATOM   5749 C CA    . GLN A 1 750 ? 128.066 164.857 148.575 1.00 187.40 ? 755 GLN M CA    1 
ATOM   5750 C C     . GLN A 1 750 ? 126.936 165.067 149.570 1.00 187.40 ? 755 GLN M C     1 
ATOM   5751 O O     . GLN A 1 750 ? 126.563 166.216 149.829 1.00 187.40 ? 755 GLN M O     1 
ATOM   5752 C CB    . GLN A 1 750 ? 127.509 164.906 147.152 1.00 187.40 ? 755 GLN M CB    1 
ATOM   5753 C CG    . GLN A 1 750 ? 128.553 164.679 146.083 1.00 187.40 ? 755 GLN M CG    1 
ATOM   5754 C CD    . GLN A 1 750 ? 128.010 164.903 144.692 1.00 187.40 ? 755 GLN M CD    1 
ATOM   5755 O OE1   . GLN A 1 750 ? 126.942 165.489 144.519 1.00 187.40 ? 755 GLN M OE1   1 
ATOM   5756 N NE2   . GLN A 1 750 ? 128.744 164.435 143.689 1.00 187.40 ? 755 GLN M NE2   1 
ATOM   5757 N N     . TYR A 1 751 ? 126.398 163.995 150.147 1.00 187.55 ? 756 TYR M N     1 
ATOM   5758 C CA    . TYR A 1 751 ? 125.347 164.099 151.147 1.00 187.55 ? 756 TYR M CA    1 
ATOM   5759 C C     . TYR A 1 751 ? 125.754 163.299 152.373 1.00 187.55 ? 756 TYR M C     1 
ATOM   5760 O O     . TYR A 1 751 ? 126.476 162.305 152.278 1.00 187.55 ? 756 TYR M O     1 
ATOM   5761 C CB    . TYR A 1 751 ? 123.998 163.593 150.619 1.00 187.55 ? 756 TYR M CB    1 
ATOM   5762 C CG    . TYR A 1 751 ? 123.757 162.119 150.852 1.00 187.55 ? 756 TYR M CG    1 
ATOM   5763 C CD1   . TYR A 1 751 ? 124.367 161.161 150.056 1.00 187.55 ? 756 TYR M CD1   1 
ATOM   5764 C CD2   . TYR A 1 751 ? 122.917 161.685 151.870 1.00 187.55 ? 756 TYR M CD2   1 
ATOM   5765 C CE1   . TYR A 1 751 ? 124.150 159.813 150.270 1.00 187.55 ? 756 TYR M CE1   1 
ATOM   5766 C CE2   . TYR A 1 751 ? 122.695 160.344 152.093 1.00 187.55 ? 756 TYR M CE2   1 
ATOM   5767 C CZ    . TYR A 1 751 ? 123.311 159.411 151.289 1.00 187.55 ? 756 TYR M CZ    1 
ATOM   5768 O OH    . TYR A 1 751 ? 123.091 158.070 151.505 1.00 187.55 ? 756 TYR M OH    1 
ATOM   5769 N N     . LYS A 1 752 ? 125.283 163.743 153.533 1.00 183.96 ? 757 LYS M N     1 
ATOM   5770 C CA    . LYS A 1 752 ? 125.545 163.048 154.786 1.00 183.96 ? 757 LYS M CA    1 
ATOM   5771 C C     . LYS A 1 752 ? 124.215 162.588 155.361 1.00 183.96 ? 757 LYS M C     1 
ATOM   5772 O O     . LYS A 1 752 ? 123.331 163.410 155.627 1.00 183.96 ? 757 LYS M O     1 
ATOM   5773 C CB    . LYS A 1 752 ? 126.288 163.944 155.775 1.00 183.96 ? 757 LYS M CB    1 
ATOM   5774 C CG    . LYS A 1 752 ? 127.206 163.173 156.707 1.00 183.96 ? 757 LYS M CG    1 
ATOM   5775 C CD    . LYS A 1 752 ? 128.348 164.038 157.222 1.00 183.96 ? 757 LYS M CD    1 
ATOM   5776 C CE    . LYS A 1 752 ? 127.844 165.315 157.875 1.00 183.96 ? 757 LYS M CE    1 
ATOM   5777 N NZ    . LYS A 1 752 ? 127.487 165.098 159.300 1.00 183.96 ? 757 LYS M NZ    1 
ATOM   5778 N N     . PHE A 1 753 ? 124.080 161.280 155.554 1.00 186.59 ? 758 PHE M N     1 
ATOM   5779 C CA    . PHE A 1 753 ? 122.814 160.689 155.968 1.00 186.59 ? 758 PHE M CA    1 
ATOM   5780 C C     . PHE A 1 753 ? 122.649 160.810 157.477 1.00 186.59 ? 758 PHE M C     1 
ATOM   5781 O O     . PHE A 1 753 ? 123.402 160.195 158.239 1.00 186.59 ? 758 PHE M O     1 
ATOM   5782 C CB    . PHE A 1 753 ? 122.760 159.227 155.537 1.00 186.59 ? 758 PHE M CB    1 
ATOM   5783 C CG    . PHE A 1 753 ? 121.384 158.645 155.537 1.00 186.59 ? 758 PHE M CG    1 
ATOM   5784 C CD1   . PHE A 1 753 ? 120.614 158.665 154.388 1.00 186.59 ? 758 PHE M CD1   1 
ATOM   5785 C CD2   . PHE A 1 753 ? 120.861 158.067 156.683 1.00 186.59 ? 758 PHE M CD2   1 
ATOM   5786 C CE1   . PHE A 1 753 ? 119.345 158.124 154.380 1.00 186.59 ? 758 PHE M CE1   1 
ATOM   5787 C CE2   . PHE A 1 753 ? 119.593 157.524 156.683 1.00 186.59 ? 758 PHE M CE2   1 
ATOM   5788 C CZ    . PHE A 1 753 ? 118.833 157.553 155.528 1.00 186.59 ? 758 PHE M CZ    1 
ATOM   5789 N N     . GLY A 1 754 ? 121.652 161.584 157.908 1.00 185.41 ? 759 GLY M N     1 
ATOM   5790 C CA    . GLY A 1 754 ? 121.341 161.747 159.309 1.00 185.41 ? 759 GLY M CA    1 
ATOM   5791 C C     . GLY A 1 754 ? 120.093 160.967 159.698 1.00 185.41 ? 759 GLY M C     1 
ATOM   5792 O O     . GLY A 1 754 ? 119.400 160.389 158.865 1.00 185.41 ? 759 GLY M O     1 
ATOM   5793 N N     . HIS A 1 755 ? 119.819 160.955 161.003 1.00 183.72 ? 760 HIS M N     1 
ATOM   5794 C CA    . HIS A 1 755 ? 118.711 160.163 161.516 1.00 183.72 ? 760 HIS M CA    1 
ATOM   5795 C C     . HIS A 1 755 ? 117.437 160.970 161.734 1.00 183.72 ? 760 HIS M C     1 
ATOM   5796 O O     . HIS A 1 755 ? 116.366 160.373 161.879 1.00 183.72 ? 760 HIS M O     1 
ATOM   5797 C CB    . HIS A 1 755 ? 119.113 159.457 162.818 1.00 183.72 ? 760 HIS M CB    1 
ATOM   5798 C CG    . HIS A 1 755 ? 118.999 160.312 164.040 1.00 183.72 ? 760 HIS M CG    1 
ATOM   5799 N ND1   . HIS A 1 755 ? 119.785 161.423 164.250 1.00 183.72 ? 760 HIS M ND1   1 
ATOM   5800 C CD2   . HIS A 1 755 ? 118.201 160.204 165.127 1.00 183.72 ? 760 HIS M CD2   1 
ATOM   5801 C CE1   . HIS A 1 755 ? 119.470 161.968 165.411 1.00 183.72 ? 760 HIS M CE1   1 
ATOM   5802 N NE2   . HIS A 1 755 ? 118.510 161.248 165.963 1.00 183.72 ? 760 HIS M NE2   1 
ATOM   5803 N N     . THR A 1 756 ? 117.518 162.299 161.761 1.00 183.72 ? 761 THR M N     1 
ATOM   5804 C CA    . THR A 1 756 ? 116.328 163.135 161.670 1.00 183.72 ? 761 THR M CA    1 
ATOM   5805 C C     . THR A 1 756 ? 116.371 164.044 160.453 1.00 183.72 ? 761 THR M C     1 
ATOM   5806 O O     . THR A 1 756 ? 115.324 164.332 159.863 1.00 183.72 ? 761 THR M O     1 
ATOM   5807 C CB    . THR A 1 756 ? 116.128 163.966 162.952 1.00 183.72 ? 761 THR M CB    1 
ATOM   5808 O OG1   . THR A 1 756 ? 114.863 164.635 162.895 1.00 183.72 ? 761 THR M OG1   1 
ATOM   5809 C CG2   . THR A 1 756 ? 117.200 165.013 163.102 1.00 183.72 ? 761 THR M CG2   1 
ATOM   5810 N N     . LYS A 1 757 ? 117.555 164.507 160.063 1.00 184.62 ? 762 LYS M N     1 
ATOM   5811 C CA    . LYS A 1 757 ? 117.744 165.319 158.872 1.00 184.62 ? 762 LYS M CA    1 
ATOM   5812 C C     . LYS A 1 757 ? 118.911 164.769 158.066 1.00 184.62 ? 762 LYS M C     1 
ATOM   5813 O O     . LYS A 1 757 ? 119.941 164.392 158.632 1.00 184.62 ? 762 LYS M O     1 
ATOM   5814 C CB    . LYS A 1 757 ? 118.014 166.783 159.232 1.00 184.62 ? 762 LYS M CB    1 
ATOM   5815 C CG    . LYS A 1 757 ? 117.003 167.401 160.175 1.00 184.62 ? 762 LYS M CG    1 
ATOM   5816 C CD    . LYS A 1 757 ? 117.393 168.822 160.536 1.00 184.62 ? 762 LYS M CD    1 
ATOM   5817 C CE    . LYS A 1 757 ? 116.478 169.384 161.608 1.00 184.62 ? 762 LYS M CE    1 
ATOM   5818 N NZ    . LYS A 1 757 ? 116.961 170.692 162.121 1.00 184.62 ? 762 LYS M NZ    1 
ATOM   5819 N N     . VAL A 1 758 ? 118.758 164.738 156.747 1.00 185.88 ? 763 VAL M N     1 
ATOM   5820 C CA    . VAL A 1 758 ? 119.808 164.294 155.837 1.00 185.88 ? 763 VAL M CA    1 
ATOM   5821 C C     . VAL A 1 758 ? 120.423 165.517 155.163 1.00 185.88 ? 763 VAL M C     1 
ATOM   5822 O O     . VAL A 1 758 ? 119.707 166.357 154.604 1.00 185.88 ? 763 VAL M O     1 
ATOM   5823 C CB    . VAL A 1 758 ? 119.268 163.273 154.818 1.00 185.88 ? 763 VAL M CB    1 
ATOM   5824 C CG1   . VAL A 1 758 ? 118.082 163.834 154.058 1.00 185.88 ? 763 VAL M CG1   1 
ATOM   5825 C CG2   . VAL A 1 758 ? 120.361 162.860 153.860 1.00 185.88 ? 763 VAL M CG2   1 
ATOM   5826 N N     . PHE A 1 759 ? 121.750 165.617 155.225 1.00 182.91 ? 764 PHE M N     1 
ATOM   5827 C CA    . PHE A 1 759 ? 122.462 166.856 154.931 1.00 182.91 ? 764 PHE M CA    1 
ATOM   5828 C C     . PHE A 1 759 ? 122.909 166.909 153.475 1.00 182.91 ? 764 PHE M C     1 
ATOM   5829 O O     . PHE A 1 759 ? 123.501 165.953 152.965 1.00 182.91 ? 764 PHE M O     1 
ATOM   5830 C CB    . PHE A 1 759 ? 123.672 166.993 155.853 1.00 182.91 ? 764 PHE M CB    1 
ATOM   5831 C CG    . PHE A 1 759 ? 123.320 167.104 157.310 1.00 182.91 ? 764 PHE M CG    1 
ATOM   5832 C CD1   . PHE A 1 759 ? 122.315 167.954 157.730 1.00 182.91 ? 764 PHE M CD1   1 
ATOM   5833 C CD2   . PHE A 1 759 ? 123.994 166.355 158.260 1.00 182.91 ? 764 PHE M CD2   1 
ATOM   5834 C CE1   . PHE A 1 759 ? 121.993 168.066 159.070 1.00 182.91 ? 764 PHE M CE1   1 
ATOM   5835 C CE2   . PHE A 1 759 ? 123.677 166.459 159.600 1.00 182.91 ? 764 PHE M CE2   1 
ATOM   5836 C CZ    . PHE A 1 759 ? 122.674 167.314 160.005 1.00 182.91 ? 764 PHE M CZ    1 
ATOM   5837 N N     . PHE A 1 760 ? 122.645 168.042 152.819 1.00 185.19 ? 765 PHE M N     1 
ATOM   5838 C CA    . PHE A 1 760 ? 122.957 168.236 151.410 1.00 185.19 ? 765 PHE M CA    1 
ATOM   5839 C C     . PHE A 1 760 ? 123.688 169.553 151.201 1.00 185.19 ? 765 PHE M C     1 
ATOM   5840 O O     . PHE A 1 760 ? 123.623 170.459 152.034 1.00 185.19 ? 765 PHE M O     1 
ATOM   5841 C CB    . PHE A 1 760 ? 121.693 168.221 150.555 1.00 185.19 ? 765 PHE M CB    1 
ATOM   5842 C CG    . PHE A 1 760 ? 120.908 166.955 150.670 1.00 185.19 ? 765 PHE M CG    1 
ATOM   5843 C CD1   . PHE A 1 760 ? 121.363 165.788 150.086 1.00 185.19 ? 765 PHE M CD1   1 
ATOM   5844 C CD2   . PHE A 1 760 ? 119.720 166.930 151.368 1.00 185.19 ? 765 PHE M CD2   1 
ATOM   5845 C CE1   . PHE A 1 760 ? 120.650 164.621 150.191 1.00 185.19 ? 765 PHE M CE1   1 
ATOM   5846 C CE2   . PHE A 1 760 ? 119.003 165.769 151.473 1.00 185.19 ? 765 PHE M CE2   1 
ATOM   5847 C CZ    . PHE A 1 760 ? 119.469 164.609 150.884 1.00 185.19 ? 765 PHE M CZ    1 
ATOM   5848 N N     . LYS A 1 761 ? 124.383 169.651 150.072 1.00 183.92 ? 766 LYS M N     1 
ATOM   5849 C CA    . LYS A 1 761 ? 125.156 170.832 149.723 1.00 183.92 ? 766 LYS M CA    1 
ATOM   5850 C C     . LYS A 1 761 ? 124.472 171.628 148.610 1.00 183.92 ? 766 LYS M C     1 
ATOM   5851 O O     . LYS A 1 761 ? 123.380 171.296 148.135 1.00 183.92 ? 766 LYS M O     1 
ATOM   5852 C CB    . LYS A 1 761 ? 126.574 170.438 149.296 1.00 183.92 ? 766 LYS M CB    1 
ATOM   5853 C CG    . LYS A 1 761 ? 127.640 171.464 149.619 1.00 183.92 ? 766 LYS M CG    1 
ATOM   5854 C CD    . LYS A 1 761 ? 128.225 171.210 150.986 1.00 183.92 ? 766 LYS M CD    1 
ATOM   5855 C CE    . LYS A 1 761 ? 129.139 169.996 150.953 1.00 183.92 ? 766 LYS M CE    1 
ATOM   5856 N NZ    . LYS A 1 761 ? 129.744 169.716 152.278 1.00 183.92 ? 766 LYS M NZ    1 
ATOM   5857 N N     . ALA A 1 762 ? 125.152 172.702 148.199 1.00 185.70 ? 767 ALA M N     1 
ATOM   5858 C CA    . ALA A 1 762 ? 124.618 173.608 147.187 1.00 185.70 ? 767 ALA M CA    1 
ATOM   5859 C C     . ALA A 1 762 ? 124.349 172.884 145.874 1.00 185.70 ? 767 ALA M C     1 
ATOM   5860 O O     . ALA A 1 762 ? 123.274 173.034 145.278 1.00 185.70 ? 767 ALA M O     1 
ATOM   5861 C CB    . ALA A 1 762 ? 125.591 174.770 146.973 1.00 185.70 ? 767 ALA M CB    1 
ATOM   5862 N N     . GLY A 1 763 ? 125.327 172.109 145.399 1.00 188.67 ? 768 GLY M N     1 
ATOM   5863 C CA    . GLY A 1 763 ? 125.147 171.393 144.146 1.00 188.67 ? 768 GLY M CA    1 
ATOM   5864 C C     . GLY A 1 763 ? 124.020 170.382 144.212 1.00 188.67 ? 768 GLY M C     1 
ATOM   5865 O O     . GLY A 1 763 ? 123.266 170.213 143.250 1.00 188.67 ? 768 GLY M O     1 
ATOM   5866 N N     . LEU A 1 764 ? 123.882 169.707 145.354 1.00 188.77 ? 769 LEU M N     1 
ATOM   5867 C CA    . LEU A 1 764 ? 122.795 168.748 145.519 1.00 188.77 ? 769 LEU M CA    1 
ATOM   5868 C C     . LEU A 1 764 ? 121.442 169.440 145.469 1.00 188.77 ? 769 LEU M C     1 
ATOM   5869 O O     . LEU A 1 764 ? 120.516 168.958 144.807 1.00 188.77 ? 769 LEU M O     1 
ATOM   5870 C CB    . LEU A 1 764 ? 122.966 167.978 146.827 1.00 188.77 ? 769 LEU M CB    1 
ATOM   5871 C CG    . LEU A 1 764 ? 124.201 167.074 146.912 1.00 188.77 ? 769 LEU M CG    1 
ATOM   5872 C CD1   . LEU A 1 764 ? 125.460 167.839 147.277 1.00 188.77 ? 769 LEU M CD1   1 
ATOM   5873 C CD2   . LEU A 1 764 ? 123.962 165.956 147.907 1.00 188.77 ? 769 LEU M CD2   1 
ATOM   5874 N N     . LEU A 1 765 ? 121.308 170.578 146.155 1.00 188.90 ? 770 LEU M N     1 
ATOM   5875 C CA    . LEU A 1 765 ? 120.057 171.326 146.078 1.00 188.90 ? 770 LEU M CA    1 
ATOM   5876 C C     . LEU A 1 765 ? 119.768 171.776 144.652 1.00 188.90 ? 770 LEU M C     1 
ATOM   5877 O O     . LEU A 1 765 ? 118.628 171.676 144.183 1.00 188.90 ? 770 LEU M O     1 
ATOM   5878 C CB    . LEU A 1 765 ? 120.086 172.522 147.029 1.00 188.90 ? 770 LEU M CB    1 
ATOM   5879 C CG    . LEU A 1 765 ? 119.487 172.277 148.414 1.00 188.90 ? 770 LEU M CG    1 
ATOM   5880 C CD1   . LEU A 1 765 ? 117.993 172.071 148.293 1.00 188.90 ? 770 LEU M CD1   1 
ATOM   5881 C CD2   . LEU A 1 765 ? 120.125 171.075 149.080 1.00 188.90 ? 770 LEU M CD2   1 
ATOM   5882 N N     . GLY A 1 766 ? 120.788 172.260 143.940 1.00 191.80 ? 771 GLY M N     1 
ATOM   5883 C CA    . GLY A 1 766 ? 120.572 172.686 142.565 1.00 191.80 ? 771 GLY M CA    1 
ATOM   5884 C C     . GLY A 1 766 ? 120.124 171.548 141.666 1.00 191.80 ? 771 GLY M C     1 
ATOM   5885 O O     . GLY A 1 766 ? 119.193 171.699 140.869 1.00 191.80 ? 771 GLY M O     1 
ATOM   5886 N N     . LEU A 1 767 ? 120.768 170.386 141.797 1.00 194.22 ? 772 LEU M N     1 
ATOM   5887 C CA    . LEU A 1 767 ? 120.424 169.248 140.952 1.00 194.22 ? 772 LEU M CA    1 
ATOM   5888 C C     . LEU A 1 767 ? 119.031 168.719 141.271 1.00 194.22 ? 772 LEU M C     1 
ATOM   5889 O O     . LEU A 1 767 ? 118.269 168.375 140.357 1.00 194.22 ? 772 LEU M O     1 
ATOM   5890 C CB    . LEU A 1 767 ? 121.469 168.144 141.109 1.00 194.22 ? 772 LEU M CB    1 
ATOM   5891 C CG    . LEU A 1 767 ? 121.573 167.144 139.954 1.00 194.22 ? 772 LEU M CG    1 
ATOM   5892 C CD1   . LEU A 1 767 ? 122.015 167.846 138.678 1.00 194.22 ? 772 LEU M CD1   1 
ATOM   5893 C CD2   . LEU A 1 767 ? 122.517 166.001 140.303 1.00 194.22 ? 772 LEU M CD2   1 
ATOM   5894 N N     . LEU A 1 768 ? 118.678 168.642 142.558 1.00 194.97 ? 773 LEU M N     1 
ATOM   5895 C CA    . LEU A 1 768 ? 117.332 168.202 142.918 1.00 194.97 ? 773 LEU M CA    1 
ATOM   5896 C C     . LEU A 1 768 ? 116.281 169.191 142.427 1.00 194.97 ? 773 LEU M C     1 
ATOM   5897 O O     . LEU A 1 768 ? 115.216 168.785 141.945 1.00 194.97 ? 773 LEU M O     1 
ATOM   5898 C CB    . LEU A 1 768 ? 117.222 167.995 144.429 1.00 194.97 ? 773 LEU M CB    1 
ATOM   5899 C CG    . LEU A 1 768 ? 117.627 166.625 144.993 1.00 194.97 ? 773 LEU M CG    1 
ATOM   5900 C CD1   . LEU A 1 768 ? 119.036 166.214 144.583 1.00 194.97 ? 773 LEU M CD1   1 
ATOM   5901 C CD2   . LEU A 1 768 ? 117.467 166.584 146.509 1.00 194.97 ? 773 LEU M CD2   1 
ATOM   5902 N N     . GLU A 1 769 ? 116.572 170.491 142.524 1.00 195.20 ? 774 GLU M N     1 
ATOM   5903 C CA    . GLU A 1 769 ? 115.690 171.508 141.961 1.00 195.20 ? 774 GLU M CA    1 
ATOM   5904 C C     . GLU A 1 769 ? 115.494 171.296 140.466 1.00 195.20 ? 774 GLU M C     1 
ATOM   5905 O O     . GLU A 1 769 ? 114.368 171.357 139.958 1.00 195.20 ? 774 GLU M O     1 
ATOM   5906 C CB    . GLU A 1 769 ? 116.267 172.897 142.239 1.00 195.20 ? 774 GLU M CB    1 
ATOM   5907 C CG    . GLU A 1 769 ? 115.934 173.944 141.189 1.00 195.20 ? 774 GLU M CG    1 
ATOM   5908 C CD    . GLU A 1 769 ? 114.493 174.404 141.252 1.00 195.20 ? 774 GLU M CD    1 
ATOM   5909 O OE1   . GLU A 1 769 ? 113.915 174.401 142.360 1.00 195.20 ? 774 GLU M OE1   1 
ATOM   5910 O OE2   . GLU A 1 769 ? 113.939 174.770 140.194 1.00 195.20 ? 774 GLU M OE2   1 
ATOM   5911 N N     . GLU A 1 770 ? 116.587 171.039 139.744 1.00 195.62 ? 775 GLU M N     1 
ATOM   5912 C CA    . GLU A 1 770 ? 116.491 170.889 138.296 1.00 195.62 ? 775 GLU M CA    1 
ATOM   5913 C C     . GLU A 1 770 ? 115.681 169.656 137.918 1.00 195.62 ? 775 GLU M C     1 
ATOM   5914 O O     . GLU A 1 770 ? 114.853 169.702 136.996 1.00 195.62 ? 775 GLU M O     1 
ATOM   5915 C CB    . GLU A 1 770 ? 117.888 170.823 137.686 1.00 195.62 ? 775 GLU M CB    1 
ATOM   5916 C CG    . GLU A 1 770 ? 118.465 172.182 137.329 1.00 195.62 ? 775 GLU M CG    1 
ATOM   5917 C CD    . GLU A 1 770 ? 117.691 172.876 136.230 1.00 195.62 ? 775 GLU M CD    1 
ATOM   5918 O OE1   . GLU A 1 770 ? 118.146 172.833 135.069 1.00 195.62 ? 775 GLU M OE1   1 
ATOM   5919 O OE2   . GLU A 1 770 ? 116.632 173.470 136.524 1.00 195.62 ? 775 GLU M OE2   1 
ATOM   5920 N N     . MET A 1 771 ? 115.904 168.541 138.616 1.00 197.41 ? 776 MET M N     1 
ATOM   5921 C CA    . MET A 1 771 ? 115.166 167.333 138.270 1.00 197.41 ? 776 MET M CA    1 
ATOM   5922 C C     . MET A 1 771 ? 113.701 167.431 138.678 1.00 197.41 ? 776 MET M C     1 
ATOM   5923 O O     . MET A 1 771 ? 112.839 166.882 137.987 1.00 197.41 ? 776 MET M O     1 
ATOM   5924 C CB    . MET A 1 771 ? 115.835 166.098 138.867 1.00 197.41 ? 776 MET M CB    1 
ATOM   5925 C CG    . MET A 1 771 ? 115.980 166.088 140.362 1.00 197.41 ? 776 MET M CG    1 
ATOM   5926 S SD    . MET A 1 771 ? 117.418 165.100 140.811 1.00 197.41 ? 776 MET M SD    1 
ATOM   5927 C CE    . MET A 1 771 ? 117.293 163.778 139.607 1.00 197.41 ? 776 MET M CE    1 
ATOM   5928 N N     . ARG A 1 772 ? 113.385 168.162 139.751 1.00 197.21 ? 777 ARG M N     1 
ATOM   5929 C CA    . ARG A 1 772 ? 111.985 168.491 140.012 1.00 197.21 ? 777 ARG M CA    1 
ATOM   5930 C C     . ARG A 1 772 ? 111.392 169.322 138.881 1.00 197.21 ? 777 ARG M C     1 
ATOM   5931 O O     . ARG A 1 772 ? 110.267 169.064 138.431 1.00 197.21 ? 777 ARG M O     1 
ATOM   5932 C CB    . ARG A 1 772 ? 111.848 169.251 141.325 1.00 197.21 ? 777 ARG M CB    1 
ATOM   5933 C CG    . ARG A 1 772 ? 111.377 168.434 142.504 1.00 197.21 ? 777 ARG M CG    1 
ATOM   5934 C CD    . ARG A 1 772 ? 110.930 169.366 143.626 1.00 197.21 ? 777 ARG M CD    1 
ATOM   5935 N NE    . ARG A 1 772 ? 111.966 170.326 144.004 1.00 197.21 ? 777 ARG M NE    1 
ATOM   5936 C CZ    . ARG A 1 772 ? 111.973 171.608 143.648 1.00 197.21 ? 777 ARG M CZ    1 
ATOM   5937 N NH1   . ARG A 1 772 ? 110.995 172.095 142.897 1.00 197.21 ? 777 ARG M NH1   1 
ATOM   5938 N NH2   . ARG A 1 772 ? 112.962 172.402 144.040 1.00 197.21 ? 777 ARG M NH2   1 
ATOM   5939 N N     . ASP A 1 773 ? 112.127 170.338 138.423 1.00 197.10 ? 778 ASP M N     1 
ATOM   5940 C CA    . ASP A 1 773 ? 111.607 171.211 137.377 1.00 197.10 ? 778 ASP M CA    1 
ATOM   5941 C C     . ASP A 1 773 ? 111.310 170.429 136.103 1.00 197.10 ? 778 ASP M C     1 
ATOM   5942 O O     . ASP A 1 773 ? 110.281 170.652 135.454 1.00 197.10 ? 778 ASP M O     1 
ATOM   5943 C CB    . ASP A 1 773 ? 112.598 172.341 137.099 1.00 197.10 ? 778 ASP M CB    1 
ATOM   5944 C CG    . ASP A 1 773 ? 112.040 173.384 136.159 1.00 197.10 ? 778 ASP M CG    1 
ATOM   5945 O OD1   . ASP A 1 773 ? 111.302 174.275 136.628 1.00 197.10 ? 778 ASP M OD1   1 
ATOM   5946 O OD2   . ASP A 1 773 ? 112.337 173.308 134.950 1.00 197.10 ? 778 ASP M OD2   1 
ATOM   5947 N N     . GLU A 1 774 ? 112.195 169.502 135.731 1.00 197.61 ? 779 GLU M N     1 
ATOM   5948 C CA    . GLU A 1 774 ? 111.916 168.682 134.556 1.00 197.61 ? 779 GLU M CA    1 
ATOM   5949 C C     . GLU A 1 774 ? 110.836 167.644 134.847 1.00 197.61 ? 779 GLU M C     1 
ATOM   5950 O O     . GLU A 1 774 ? 110.120 167.223 133.930 1.00 197.61 ? 779 GLU M O     1 
ATOM   5951 C CB    . GLU A 1 774 ? 113.196 168.016 134.049 1.00 197.61 ? 779 GLU M CB    1 
ATOM   5952 C CG    . GLU A 1 774 ? 113.849 167.067 135.026 1.00 197.61 ? 779 GLU M CG    1 
ATOM   5953 C CD    . GLU A 1 774 ? 113.540 165.613 134.735 1.00 197.61 ? 779 GLU M CD    1 
ATOM   5954 O OE1   . GLU A 1 774 ? 113.163 165.303 133.587 1.00 197.61 ? 779 GLU M OE1   1 
ATOM   5955 O OE2   . GLU A 1 774 ? 113.680 164.779 135.654 1.00 197.61 ? 779 GLU M OE2   1 
ATOM   5956 N N     . ARG A 1 775 ? 110.694 167.232 136.109 1.00 197.03 ? 780 ARG M N     1 
ATOM   5957 C CA    . ARG A 1 775 ? 109.589 166.362 136.488 1.00 197.03 ? 780 ARG M CA    1 
ATOM   5958 C C     . ARG A 1 775 ? 108.252 167.052 136.259 1.00 197.03 ? 780 ARG M C     1 
ATOM   5959 O O     . ARG A 1 775 ? 107.265 166.406 135.889 1.00 197.03 ? 780 ARG M O     1 
ATOM   5960 C CB    . ARG A 1 775 ? 109.736 165.952 137.951 1.00 197.03 ? 780 ARG M CB    1 
ATOM   5961 C CG    . ARG A 1 775 ? 108.757 164.901 138.405 1.00 197.03 ? 780 ARG M CG    1 
ATOM   5962 C CD    . ARG A 1 775 ? 109.051 163.592 137.719 1.00 197.03 ? 780 ARG M CD    1 
ATOM   5963 N NE    . ARG A 1 775 ? 110.481 163.308 137.733 1.00 197.03 ? 780 ARG M NE    1 
ATOM   5964 C CZ    . ARG A 1 775 ? 111.043 162.288 137.095 1.00 197.03 ? 780 ARG M CZ    1 
ATOM   5965 N NH1   . ARG A 1 775 ? 110.291 161.451 136.392 1.00 197.03 ? 780 ARG M NH1   1 
ATOM   5966 N NH2   . ARG A 1 775 ? 112.354 162.105 137.160 1.00 197.03 ? 780 ARG M NH2   1 
ATOM   5967 N N     . LEU A 1 776 ? 108.200 168.361 136.483 1.00 196.19 ? 781 LEU M N     1 
ATOM   5968 C CA    . LEU A 1 776 ? 106.997 169.137 136.194 1.00 196.19 ? 781 LEU M CA    1 
ATOM   5969 C C     . LEU A 1 776 ? 106.983 169.574 134.734 1.00 196.19 ? 781 LEU M C     1 
ATOM   5970 O O     . LEU A 1 776 ? 106.018 170.181 134.269 1.00 196.19 ? 781 LEU M O     1 
ATOM   5971 C CB    . LEU A 1 776 ? 106.897 170.361 137.110 1.00 196.19 ? 781 LEU M CB    1 
ATOM   5972 C CG    . LEU A 1 776 ? 106.244 170.145 138.477 1.00 196.19 ? 781 LEU M CG    1 
ATOM   5973 C CD1   . LEU A 1 776 ? 107.143 169.335 139.400 1.00 196.19 ? 781 LEU M CD1   1 
ATOM   5974 C CD2   . LEU A 1 776 ? 105.872 171.475 139.115 1.00 196.19 ? 781 LEU M CD2   1 
ATOM   5975 N N     . THR B 2 1   ? 158.442 184.760 181.716 1.00 62.60  ? 5   THR F N     1 
ATOM   5976 C CA    . THR B 2 1   ? 159.619 184.768 182.575 1.00 62.60  ? 5   THR F CA    1 
ATOM   5977 C C     . THR B 2 1   ? 160.443 186.033 182.382 1.00 62.60  ? 5   THR F C     1 
ATOM   5978 O O     . THR B 2 1   ? 160.447 186.626 181.308 1.00 62.60  ? 5   THR F O     1 
ATOM   5979 C CB    . THR B 2 1   ? 160.511 183.544 182.318 1.00 62.60  ? 5   THR F CB    1 
ATOM   5980 O OG1   . THR B 2 1   ? 161.610 183.554 183.235 1.00 62.60  ? 5   THR F OG1   1 
ATOM   5981 C CG2   . THR B 2 1   ? 161.034 183.549 180.897 1.00 62.60  ? 5   THR F CG2   1 
ATOM   5982 N N     . THR B 2 2   ? 161.137 186.448 183.431 1.00 57.61  ? 6   THR F N     1 
ATOM   5983 C CA    . THR B 2 2   ? 161.958 187.644 183.385 1.00 57.61  ? 6   THR F CA    1 
ATOM   5984 C C     . THR B 2 2   ? 163.396 187.310 183.744 1.00 57.61  ? 6   THR F C     1 
ATOM   5985 O O     . THR B 2 2   ? 163.672 186.317 184.420 1.00 57.61  ? 6   THR F O     1 
ATOM   5986 C CB    . THR B 2 2   ? 161.424 188.725 184.321 1.00 57.61  ? 6   THR F CB    1 
ATOM   5987 O OG1   . THR B 2 2   ? 162.239 189.898 184.208 1.00 57.61  ? 6   THR F OG1   1 
ATOM   5988 C CG2   . THR B 2 2   ? 161.412 188.234 185.754 1.00 57.61  ? 6   THR F CG2   1 
ATOM   5989 N N     . ALA B 2 3   ? 164.309 188.141 183.269 1.00 50.81  ? 7   ALA F N     1 
ATOM   5990 C CA    . ALA B 2 3   ? 165.727 187.922 183.466 1.00 50.81  ? 7   ALA F CA    1 
ATOM   5991 C C     . ALA B 2 3   ? 166.251 188.752 184.627 1.00 50.81  ? 7   ALA F C     1 
ATOM   5992 O O     . ALA B 2 3   ? 165.658 189.751 185.031 1.00 50.81  ? 7   ALA F O     1 
ATOM   5993 C CB    . ALA B 2 3   ? 166.496 188.262 182.197 1.00 50.81  ? 7   ALA F CB    1 
ATOM   5994 N N     . LEU B 2 4   ? 167.394 188.327 185.148 1.00 46.75  ? 8   LEU F N     1 
ATOM   5995 C CA    . LEU B 2 4   ? 168.096 189.001 186.230 1.00 46.75  ? 8   LEU F CA    1 
ATOM   5996 C C     . LEU B 2 4   ? 169.339 189.650 185.661 1.00 46.75  ? 8   LEU F C     1 
ATOM   5997 O O     . LEU B 2 4   ? 170.114 188.998 184.960 1.00 46.75  ? 8   LEU F O     1 
ATOM   5998 C CB    . LEU B 2 4   ? 168.472 188.015 187.331 1.00 46.75  ? 8   LEU F CB    1 
ATOM   5999 C CG    . LEU B 2 4   ? 167.499 187.800 188.477 1.00 46.75  ? 8   LEU F CG    1 
ATOM   6000 C CD1   . LEU B 2 4   ? 166.192 187.330 187.981 1.00 46.75  ? 8   LEU F CD1   1 
ATOM   6001 C CD2   . LEU B 2 4   ? 168.081 186.749 189.363 1.00 46.75  ? 8   LEU F CD2   1 
ATOM   6002 N N     . VAL B 2 5   ? 169.526 190.925 185.949 1.00 42.72  ? 9   VAL F N     1 
ATOM   6003 C CA    . VAL B 2 5   ? 170.705 191.652 185.512 1.00 42.72  ? 9   VAL F CA    1 
ATOM   6004 C C     . VAL B 2 5   ? 171.568 191.900 186.734 1.00 42.72  ? 9   VAL F C     1 
ATOM   6005 O O     . VAL B 2 5   ? 171.288 192.801 187.528 1.00 42.72  ? 9   VAL F O     1 
ATOM   6006 C CB    . VAL B 2 5   ? 170.335 192.965 184.821 1.00 42.72  ? 9   VAL F CB    1 
ATOM   6007 C CG1   . VAL B 2 5   ? 171.579 193.697 184.432 1.00 42.72  ? 9   VAL F CG1   1 
ATOM   6008 C CG2   . VAL B 2 5   ? 169.499 192.686 183.615 1.00 42.72  ? 9   VAL F CG2   1 
ATOM   6009 N N     . CYS B 2 6   ? 172.629 191.122 186.878 1.00 44.09  ? 10  CYS F N     1 
ATOM   6010 C CA    . CYS B 2 6   ? 173.536 191.226 188.012 1.00 44.09  ? 10  CYS F CA    1 
ATOM   6011 C C     . CYS B 2 6   ? 174.866 191.762 187.516 1.00 44.09  ? 10  CYS F C     1 
ATOM   6012 O O     . CYS B 2 6   ? 175.662 191.016 186.945 1.00 44.09  ? 10  CYS F O     1 
ATOM   6013 C CB    . CYS B 2 6   ? 173.720 189.873 188.686 1.00 44.09  ? 10  CYS F CB    1 
ATOM   6014 S SG    . CYS B 2 6   ? 175.087 189.834 189.854 1.00 44.09  ? 10  CYS F SG    1 
ATOM   6015 N N     . ASP B 2 7   ? 175.112 193.046 187.738 1.00 42.99  ? 11  ASP F N     1 
ATOM   6016 C CA    . ASP B 2 7   ? 176.385 193.669 187.387 1.00 42.99  ? 11  ASP F CA    1 
ATOM   6017 C C     . ASP B 2 7   ? 177.287 193.585 188.611 1.00 42.99  ? 11  ASP F C     1 
ATOM   6018 O O     . ASP B 2 7   ? 177.335 194.488 189.439 1.00 42.99  ? 11  ASP F O     1 
ATOM   6019 C CB    . ASP B 2 7   ? 176.175 195.099 186.912 1.00 42.99  ? 11  ASP F CB    1 
ATOM   6020 C CG    . ASP B 2 7   ? 177.459 195.891 186.856 1.00 42.99  ? 11  ASP F CG    1 
ATOM   6021 O OD1   . ASP B 2 7   ? 177.797 196.563 187.844 1.00 42.99  ? 11  ASP F OD1   1 
ATOM   6022 O OD2   . ASP B 2 7   ? 178.165 195.807 185.839 1.00 42.99  ? 11  ASP F OD2   1 
ATOM   6023 N N     . ASN B 2 8   ? 178.017 192.477 188.716 1.00 43.96  ? 12  ASN F N     1 
ATOM   6024 C CA    . ASN B 2 8   ? 178.731 192.176 189.948 1.00 43.96  ? 12  ASN F CA    1 
ATOM   6025 C C     . ASN B 2 8   ? 179.832 193.177 190.244 1.00 43.96  ? 12  ASN F C     1 
ATOM   6026 O O     . ASN B 2 8   ? 180.268 193.272 191.393 1.00 43.96  ? 12  ASN F O     1 
ATOM   6027 C CB    . ASN B 2 8   ? 179.311 190.773 189.881 1.00 43.96  ? 12  ASN F CB    1 
ATOM   6028 C CG    . ASN B 2 8   ? 180.216 190.593 188.702 1.00 43.96  ? 12  ASN F CG    1 
ATOM   6029 O OD1   . ASN B 2 8   ? 181.089 191.418 188.444 1.00 43.96  ? 12  ASN F OD1   1 
ATOM   6030 N ND2   . ASN B 2 8   ? 179.999 189.522 187.950 1.00 43.96  ? 12  ASN F ND2   1 
ATOM   6031 N N     . GLY B 2 9   ? 180.297 193.907 189.240 1.00 43.18  ? 13  GLY F N     1 
ATOM   6032 C CA    . GLY B 2 9   ? 181.289 194.938 189.443 1.00 43.18  ? 13  GLY F CA    1 
ATOM   6033 C C     . GLY B 2 9   ? 182.500 194.417 190.184 1.00 43.18  ? 13  GLY F C     1 
ATOM   6034 O O     . GLY B 2 9   ? 182.800 193.225 190.181 1.00 43.18  ? 13  GLY F O     1 
ATOM   6035 N N     . SER B 2 10  ? 183.209 195.331 190.838 1.00 42.56  ? 14  SER F N     1 
ATOM   6036 C CA    . SER B 2 10  ? 184.336 194.948 191.681 1.00 42.56  ? 14  SER F CA    1 
ATOM   6037 C C     . SER B 2 10  ? 184.410 195.970 192.807 1.00 42.56  ? 14  SER F C     1 
ATOM   6038 O O     . SER B 2 10  ? 185.156 196.941 192.704 1.00 42.56  ? 14  SER F O     1 
ATOM   6039 C CB    . SER B 2 10  ? 185.620 194.919 190.875 1.00 42.56  ? 14  SER F CB    1 
ATOM   6040 O OG    . SER B 2 10  ? 186.745 195.051 191.711 1.00 42.56  ? 14  SER F OG    1 
ATOM   6041 N N     . GLY B 2 11  ? 183.694 195.718 193.886 1.00 40.60  ? 15  GLY F N     1 
ATOM   6042 C CA    . GLY B 2 11  ? 183.515 196.712 194.914 1.00 40.60  ? 15  GLY F CA    1 
ATOM   6043 C C     . GLY B 2 11  ? 182.097 197.191 195.099 1.00 40.60  ? 15  GLY F C     1 
ATOM   6044 O O     . GLY B 2 11  ? 181.838 197.925 196.053 1.00 40.60  ? 15  GLY F O     1 
ATOM   6045 N N     . LEU B 2 12  ? 181.176 196.806 194.223 1.00 39.01  ? 16  LEU F N     1 
ATOM   6046 C CA    . LEU B 2 12  ? 179.756 197.072 194.416 1.00 39.01  ? 16  LEU F CA    1 
ATOM   6047 C C     . LEU B 2 12  ? 178.973 196.084 193.579 1.00 39.01  ? 16  LEU F C     1 
ATOM   6048 O O     . LEU B 2 12  ? 179.189 196.000 192.372 1.00 39.01  ? 16  LEU F O     1 
ATOM   6049 C CB    . LEU B 2 12  ? 179.381 198.494 194.012 1.00 39.01  ? 16  LEU F CB    1 
ATOM   6050 C CG    . LEU B 2 12  ? 179.278 199.567 195.083 1.00 39.01  ? 16  LEU F CG    1 
ATOM   6051 C CD1   . LEU B 2 12  ? 178.673 200.803 194.496 1.00 39.01  ? 16  LEU F CD1   1 
ATOM   6052 C CD2   . LEU B 2 12  ? 178.446 199.088 196.223 1.00 39.01  ? 16  LEU F CD2   1 
ATOM   6053 N N     . VAL B 2 13  ? 178.087 195.337 194.206 1.00 38.07  ? 17  VAL F N     1 
ATOM   6054 C CA    . VAL B 2 13  ? 177.188 194.455 193.482 1.00 38.07  ? 17  VAL F CA    1 
ATOM   6055 C C     . VAL B 2 13  ? 175.902 195.210 193.221 1.00 38.07  ? 17  VAL F C     1 
ATOM   6056 O O     . VAL B 2 13  ? 175.370 195.869 194.115 1.00 38.07  ? 17  VAL F O     1 
ATOM   6057 C CB    . VAL B 2 13  ? 176.916 193.168 194.268 1.00 38.07  ? 17  VAL F CB    1 
ATOM   6058 C CG1   . VAL B 2 13  ? 175.893 192.344 193.557 1.00 38.07  ? 17  VAL F CG1   1 
ATOM   6059 C CG2   . VAL B 2 13  ? 178.170 192.383 194.409 1.00 38.07  ? 17  VAL F CG2   1 
ATOM   6060 N N     . LYS B 2 14  ? 175.415 195.137 191.991 1.00 38.06  ? 18  LYS F N     1 
ATOM   6061 C CA    . LYS B 2 14  ? 174.170 195.773 191.598 1.00 38.06  ? 18  LYS F CA    1 
ATOM   6062 C C     . LYS B 2 14  ? 173.320 194.735 190.900 1.00 38.06  ? 18  LYS F C     1 
ATOM   6063 O O     . LYS B 2 14  ? 173.722 194.205 189.867 1.00 38.06  ? 18  LYS F O     1 
ATOM   6064 C CB    . LYS B 2 14  ? 174.428 196.958 190.682 1.00 38.06  ? 18  LYS F CB    1 
ATOM   6065 C CG    . LYS B 2 14  ? 175.128 198.076 191.364 1.00 38.06  ? 18  LYS F CG    1 
ATOM   6066 C CD    . LYS B 2 14  ? 175.507 199.141 190.397 1.00 38.06  ? 18  LYS F CD    1 
ATOM   6067 C CE    . LYS B 2 14  ? 176.878 198.902 189.866 1.00 38.06  ? 18  LYS F CE    1 
ATOM   6068 N NZ    . LYS B 2 14  ? 177.890 199.191 190.891 1.00 38.06  ? 18  LYS F NZ    1 
ATOM   6069 N N     . ALA B 2 15  ? 172.156 194.442 191.457 1.00 41.45  ? 19  ALA F N     1 
ATOM   6070 C CA    . ALA B 2 15  ? 171.284 193.428 190.898 1.00 41.45  ? 19  ALA F CA    1 
ATOM   6071 C C     . ALA B 2 15  ? 169.878 193.983 190.769 1.00 41.45  ? 19  ALA F C     1 
ATOM   6072 O O     . ALA B 2 15  ? 169.561 195.064 191.262 1.00 41.45  ? 19  ALA F O     1 
ATOM   6073 C CB    . ALA B 2 15  ? 171.283 192.164 191.753 1.00 41.45  ? 19  ALA F CB    1 
ATOM   6074 N N     . GLY B 2 16  ? 169.035 193.234 190.083 1.00 45.76  ? 20  GLY F N     1 
ATOM   6075 C CA    . GLY B 2 16  ? 167.692 193.687 189.806 1.00 45.76  ? 20  GLY F CA    1 
ATOM   6076 C C     . GLY B 2 16  ? 167.071 192.821 188.735 1.00 45.76  ? 20  GLY F C     1 
ATOM   6077 O O     . GLY B 2 16  ? 167.593 191.771 188.385 1.00 45.76  ? 20  GLY F O     1 
ATOM   6078 N N     . PHE B 2 17  ? 165.936 193.281 188.237 1.00 50.75  ? 21  PHE F N     1 
ATOM   6079 C CA    . PHE B 2 17  ? 165.223 192.575 187.189 1.00 50.75  ? 21  PHE F CA    1 
ATOM   6080 C C     . PHE B 2 17  ? 165.328 193.331 185.879 1.00 50.75  ? 21  PHE F C     1 
ATOM   6081 O O     . PHE B 2 17  ? 165.362 194.559 185.854 1.00 50.75  ? 21  PHE F O     1 
ATOM   6082 C CB    . PHE B 2 17  ? 163.757 192.391 187.555 1.00 50.75  ? 21  PHE F CB    1 
ATOM   6083 C CG    . PHE B 2 17  ? 163.535 191.371 188.604 1.00 50.75  ? 21  PHE F CG    1 
ATOM   6084 C CD1   . PHE B 2 17  ? 163.170 190.093 188.269 1.00 50.75  ? 21  PHE F CD1   1 
ATOM   6085 C CD2   . PHE B 2 17  ? 163.702 191.682 189.925 1.00 50.75  ? 21  PHE F CD2   1 
ATOM   6086 C CE1   . PHE B 2 17  ? 162.973 189.158 189.232 1.00 50.75  ? 21  PHE F CE1   1 
ATOM   6087 C CE2   . PHE B 2 17  ? 163.507 190.746 190.887 1.00 50.75  ? 21  PHE F CE2   1 
ATOM   6088 C CZ    . PHE B 2 17  ? 163.142 189.486 190.539 1.00 50.75  ? 21  PHE F CZ    1 
ATOM   6089 N N     . ALA B 2 18  ? 165.377 192.582 184.786 1.00 51.25  ? 22  ALA F N     1 
ATOM   6090 C CA    . ALA B 2 18  ? 165.399 193.201 183.473 1.00 51.25  ? 22  ALA F CA    1 
ATOM   6091 C C     . ALA B 2 18  ? 164.059 193.860 183.201 1.00 51.25  ? 22  ALA F C     1 
ATOM   6092 O O     . ALA B 2 18  ? 163.006 193.244 183.372 1.00 51.25  ? 22  ALA F O     1 
ATOM   6093 C CB    . ALA B 2 18  ? 165.709 192.167 182.399 1.00 51.25  ? 22  ALA F CB    1 
ATOM   6094 N N     . GLY B 2 19  ? 164.098 195.108 182.769 1.00 57.27  ? 23  GLY F N     1 
ATOM   6095 C CA    . GLY B 2 19  ? 162.897 195.885 182.598 1.00 57.27  ? 23  GLY F CA    1 
ATOM   6096 C C     . GLY B 2 19  ? 162.680 196.932 183.655 1.00 57.27  ? 23  GLY F C     1 
ATOM   6097 O O     . GLY B 2 19  ? 161.717 197.691 183.555 1.00 57.27  ? 23  GLY F O     1 
ATOM   6098 N N     . ASP B 2 20  ? 163.549 197.009 184.652 1.00 56.22  ? 24  ASP F N     1 
ATOM   6099 C CA    . ASP B 2 20  ? 163.478 198.058 185.649 1.00 56.22  ? 24  ASP F CA    1 
ATOM   6100 C C     . ASP B 2 20  ? 164.241 199.280 185.173 1.00 56.22  ? 24  ASP F C     1 
ATOM   6101 O O     . ASP B 2 20  ? 165.012 199.233 184.218 1.00 56.22  ? 24  ASP F O     1 
ATOM   6102 C CB    . ASP B 2 20  ? 164.060 197.596 186.975 1.00 56.22  ? 24  ASP F CB    1 
ATOM   6103 C CG    . ASP B 2 20  ? 163.299 196.460 187.572 1.00 56.22  ? 24  ASP F CG    1 
ATOM   6104 O OD1   . ASP B 2 20  ? 162.109 196.322 187.261 1.00 56.22  ? 24  ASP F OD1   1 
ATOM   6105 O OD2   . ASP B 2 20  ? 163.891 195.707 188.367 1.00 56.22  ? 24  ASP F OD2   1 
ATOM   6106 N N     . ASP B 2 21  ? 164.031 200.383 185.868 1.00 57.05  ? 25  ASP F N     1 
ATOM   6107 C CA    . ASP B 2 21  ? 164.747 201.608 185.570 1.00 57.05  ? 25  ASP F CA    1 
ATOM   6108 C C     . ASP B 2 21  ? 166.016 201.761 186.391 1.00 57.05  ? 25  ASP F C     1 
ATOM   6109 O O     . ASP B 2 21  ? 166.781 202.698 186.150 1.00 57.05  ? 25  ASP F O     1 
ATOM   6110 C CB    . ASP B 2 21  ? 163.832 202.809 185.811 1.00 57.05  ? 25  ASP F CB    1 
ATOM   6111 C CG    . ASP B 2 21  ? 164.219 204.014 184.980 1.00 57.05  ? 25  ASP F CG    1 
ATOM   6112 O OD1   . ASP B 2 21  ? 165.300 203.995 184.352 1.00 57.05  ? 25  ASP F OD1   1 
ATOM   6113 O OD2   . ASP B 2 21  ? 163.441 204.990 184.962 1.00 57.05  ? 25  ASP F OD2   1 
ATOM   6114 N N     . ALA B 2 22  ? 166.263 200.874 187.344 1.00 48.69  ? 26  ALA F N     1 
ATOM   6115 C CA    . ALA B 2 22  ? 167.382 201.015 188.262 1.00 48.69  ? 26  ALA F CA    1 
ATOM   6116 C C     . ALA B 2 22  ? 167.573 199.694 188.991 1.00 48.69  ? 26  ALA F C     1 
ATOM   6117 O O     . ALA B 2 22  ? 166.644 198.895 189.073 1.00 48.69  ? 26  ALA F O     1 
ATOM   6118 C CB    . ALA B 2 22  ? 167.140 202.149 189.264 1.00 48.69  ? 26  ALA F CB    1 
ATOM   6119 N N     . PRO B 2 23  ? 168.770 199.442 189.510 1.00 44.85  ? 27  PRO F N     1 
ATOM   6120 C CA    . PRO B 2 23  ? 168.987 198.216 190.274 1.00 44.85  ? 27  PRO F CA    1 
ATOM   6121 C C     . PRO B 2 23  ? 168.192 198.225 191.560 1.00 44.85  ? 27  PRO F C     1 
ATOM   6122 O O     . PRO B 2 23  ? 167.999 199.265 192.186 1.00 44.85  ? 27  PRO F O     1 
ATOM   6123 C CB    . PRO B 2 23  ? 170.490 198.237 190.549 1.00 44.85  ? 27  PRO F CB    1 
ATOM   6124 C CG    . PRO B 2 23  ? 170.880 199.631 190.399 1.00 44.85  ? 27  PRO F CG    1 
ATOM   6125 C CD    . PRO B 2 23  ? 170.019 200.193 189.338 1.00 44.85  ? 27  PRO F CD    1 
ATOM   6126 N N     . ARG B 2 24  ? 167.726 197.049 191.956 1.00 49.72  ? 28  ARG F N     1 
ATOM   6127 C CA    . ARG B 2 24  ? 166.970 196.949 193.195 1.00 49.72  ? 28  ARG F CA    1 
ATOM   6128 C C     . ARG B 2 24  ? 167.888 196.791 194.399 1.00 49.72  ? 28  ARG F C     1 
ATOM   6129 O O     . ARG B 2 24  ? 167.633 197.371 195.456 1.00 49.72  ? 28  ARG F O     1 
ATOM   6130 C CB    . ARG B 2 24  ? 165.992 195.785 193.110 1.00 49.72  ? 28  ARG F CB    1 
ATOM   6131 C CG    . ARG B 2 24  ? 165.440 195.386 194.435 1.00 49.72  ? 28  ARG F CG    1 
ATOM   6132 C CD    . ARG B 2 24  ? 164.281 194.430 194.299 1.00 49.72  ? 28  ARG F CD    1 
ATOM   6133 N NE    . ARG B 2 24  ? 163.073 195.080 193.804 1.00 49.72  ? 28  ARG F NE    1 
ATOM   6134 C CZ    . ARG B 2 24  ? 162.556 194.857 192.604 1.00 49.72  ? 28  ARG F CZ    1 
ATOM   6135 N NH1   . ARG B 2 24  ? 163.138 193.996 191.790 1.00 49.72  ? 28  ARG F NH1   1 
ATOM   6136 N NH2   . ARG B 2 24  ? 161.456 195.483 192.220 1.00 49.72  ? 28  ARG F NH2   1 
ATOM   6137 N N     . ALA B 2 25  ? 168.962 196.026 194.254 1.00 43.66  ? 29  ALA F N     1 
ATOM   6138 C CA    . ALA B 2 25  ? 169.884 195.733 195.340 1.00 43.66  ? 29  ALA F CA    1 
ATOM   6139 C C     . ALA B 2 25  ? 171.248 196.293 194.988 1.00 43.66  ? 29  ALA F C     1 
ATOM   6140 O O     . ALA B 2 25  ? 171.816 195.928 193.959 1.00 43.66  ? 29  ALA F O     1 
ATOM   6141 C CB    . ALA B 2 25  ? 169.975 194.228 195.581 1.00 43.66  ? 29  ALA F CB    1 
ATOM   6142 N N     . VAL B 2 26  ? 171.771 197.173 195.832 1.00 40.69  ? 30  VAL F N     1 
ATOM   6143 C CA    . VAL B 2 26  ? 173.102 197.737 195.659 1.00 40.69  ? 30  VAL F CA    1 
ATOM   6144 C C     . VAL B 2 26  ? 173.808 197.684 197.001 1.00 40.69  ? 30  VAL F C     1 
ATOM   6145 O O     . VAL B 2 26  ? 173.392 198.358 197.947 1.00 40.69  ? 30  VAL F O     1 
ATOM   6146 C CB    . VAL B 2 26  ? 173.056 199.179 195.140 1.00 40.69  ? 30  VAL F CB    1 
ATOM   6147 C CG1   . VAL B 2 26  ? 174.435 199.756 195.102 1.00 40.69  ? 30  VAL F CG1   1 
ATOM   6148 C CG2   . VAL B 2 26  ? 172.459 199.210 193.780 1.00 40.69  ? 30  VAL F CG2   1 
ATOM   6149 N N     . PHE B 2 27  ? 174.874 196.902 197.083 1.00 40.65  ? 31  PHE F N     1 
ATOM   6150 C CA    . PHE B 2 27  ? 175.594 196.710 198.330 1.00 40.65  ? 31  PHE F CA    1 
ATOM   6151 C C     . PHE B 2 27  ? 177.043 196.406 198.004 1.00 40.65  ? 31  PHE F C     1 
ATOM   6152 O O     . PHE B 2 27  ? 177.351 195.984 196.886 1.00 40.65  ? 31  PHE F O     1 
ATOM   6153 C CB    . PHE B 2 27  ? 174.971 195.583 199.155 1.00 40.65  ? 31  PHE F CB    1 
ATOM   6154 C CG    . PHE B 2 27  ? 174.952 194.264 198.464 1.00 40.65  ? 31  PHE F CG    1 
ATOM   6155 C CD1   . PHE B 2 27  ? 173.902 193.906 197.661 1.00 40.65  ? 31  PHE F CD1   1 
ATOM   6156 C CD2   . PHE B 2 27  ? 175.971 193.367 198.643 1.00 40.65  ? 31  PHE F CD2   1 
ATOM   6157 C CE1   . PHE B 2 27  ? 173.881 192.693 197.044 1.00 40.65  ? 31  PHE F CE1   1 
ATOM   6158 C CE2   . PHE B 2 27  ? 175.950 192.156 198.027 1.00 40.65  ? 31  PHE F CE2   1 
ATOM   6159 C CZ    . PHE B 2 27  ? 174.906 191.820 197.228 1.00 40.65  ? 31  PHE F CZ    1 
ATOM   6160 N N     . PRO B 2 28  ? 177.960 196.621 198.941 1.00 39.14  ? 32  PRO F N     1 
ATOM   6161 C CA    . PRO B 2 28  ? 179.368 196.335 198.663 1.00 39.14  ? 32  PRO F CA    1 
ATOM   6162 C C     . PRO B 2 28  ? 179.620 194.848 198.518 1.00 39.14  ? 32  PRO F C     1 
ATOM   6163 O O     . PRO B 2 28  ? 179.000 194.023 199.186 1.00 39.14  ? 32  PRO F O     1 
ATOM   6164 C CB    . PRO B 2 28  ? 180.090 196.893 199.889 1.00 39.14  ? 32  PRO F CB    1 
ATOM   6165 C CG    . PRO B 2 28  ? 179.129 197.801 200.519 1.00 39.14  ? 32  PRO F CG    1 
ATOM   6166 C CD    . PRO B 2 28  ? 177.791 197.245 200.259 1.00 39.14  ? 32  PRO F CD    1 
ATOM   6167 N N     . SER B 2 29  ? 180.554 194.505 197.633 1.00 39.26  ? 33  SER F N     1 
ATOM   6168 C CA    . SER B 2 29  ? 180.925 193.109 197.422 1.00 39.26  ? 33  SER F CA    1 
ATOM   6169 C C     . SER B 2 29  ? 182.040 192.766 198.399 1.00 39.26  ? 33  SER F C     1 
ATOM   6170 O O     . SER B 2 29  ? 183.224 192.753 198.072 1.00 39.26  ? 33  SER F O     1 
ATOM   6171 C CB    . SER B 2 29  ? 181.339 192.867 195.982 1.00 39.26  ? 33  SER F CB    1 
ATOM   6172 O OG    . SER B 2 29  ? 182.619 193.388 195.736 1.00 39.26  ? 33  SER F OG    1 
ATOM   6173 N N     . ILE B 2 30  ? 181.636 192.478 199.628 1.00 39.51  ? 34  ILE F N     1 
ATOM   6174 C CA    . ILE B 2 30  ? 182.543 192.302 200.749 1.00 39.51  ? 34  ILE F CA    1 
ATOM   6175 C C     . ILE B 2 30  ? 182.122 191.070 201.520 1.00 39.51  ? 34  ILE F C     1 
ATOM   6176 O O     . ILE B 2 30  ? 180.927 190.818 201.690 1.00 39.51  ? 34  ILE F O     1 
ATOM   6177 C CB    . ILE B 2 30  ? 182.534 193.535 201.668 1.00 39.51  ? 34  ILE F CB    1 
ATOM   6178 C CG1   . ILE B 2 30  ? 183.208 194.712 200.993 1.00 39.51  ? 34  ILE F CG1   1 
ATOM   6179 C CG2   . ILE B 2 30  ? 183.214 193.249 202.943 1.00 39.51  ? 34  ILE F CG2   1 
ATOM   6180 C CD1   . ILE B 2 30  ? 183.052 195.968 201.759 1.00 39.51  ? 34  ILE F CD1   1 
ATOM   6181 N N     . VAL B 2 31  ? 183.097 190.291 201.970 1.00 39.31  ? 35  VAL F N     1 
ATOM   6182 C CA    . VAL B 2 31  ? 182.862 189.182 202.881 1.00 39.31  ? 35  VAL F CA    1 
ATOM   6183 C C     . VAL B 2 31  ? 183.728 189.395 204.107 1.00 39.31  ? 35  VAL F C     1 
ATOM   6184 O O     . VAL B 2 31  ? 184.955 189.469 203.997 1.00 39.31  ? 35  VAL F O     1 
ATOM   6185 C CB    . VAL B 2 31  ? 183.167 187.831 202.231 1.00 39.31  ? 35  VAL F CB    1 
ATOM   6186 C CG1   . VAL B 2 31  ? 183.008 186.736 203.242 1.00 39.31  ? 35  VAL F CG1   1 
ATOM   6187 C CG2   . VAL B 2 31  ? 182.244 187.606 201.074 1.00 39.31  ? 35  VAL F CG2   1 
ATOM   6188 N N     . GLY B 2 32  ? 183.100 189.488 205.269 1.00 40.15  ? 36  GLY F N     1 
ATOM   6189 C CA    . GLY B 2 32  ? 183.797 189.738 206.518 1.00 40.15  ? 36  GLY F CA    1 
ATOM   6190 C C     . GLY B 2 32  ? 183.797 188.499 207.394 1.00 40.15  ? 36  GLY F C     1 
ATOM   6191 O O     . GLY B 2 32  ? 182.827 187.748 207.416 1.00 40.15  ? 36  GLY F O     1 
ATOM   6192 N N     . ARG B 2 33  ? 184.898 188.289 208.099 1.00 41.23  ? 37  ARG F N     1 
ATOM   6193 C CA    . ARG B 2 33  ? 185.000 187.202 209.048 1.00 41.23  ? 37  ARG F CA    1 
ATOM   6194 C C     . ARG B 2 33  ? 185.490 187.755 210.376 1.00 41.23  ? 37  ARG F C     1 
ATOM   6195 O O     . ARG B 2 33  ? 186.333 188.656 210.397 1.00 41.23  ? 37  ARG F O     1 
ATOM   6196 C CB    . ARG B 2 33  ? 185.947 186.116 208.544 1.00 41.23  ? 37  ARG F CB    1 
ATOM   6197 C CG    . ARG B 2 33  ? 185.449 185.449 207.303 1.00 41.23  ? 37  ARG F CG    1 
ATOM   6198 C CD    . ARG B 2 33  ? 186.234 184.215 206.965 1.00 41.23  ? 37  ARG F CD    1 
ATOM   6199 N NE    . ARG B 2 33  ? 185.580 183.453 205.911 1.00 41.23  ? 37  ARG F NE    1 
ATOM   6200 C CZ    . ARG B 2 33  ? 185.724 183.703 204.618 1.00 41.23  ? 37  ARG F CZ    1 
ATOM   6201 N NH1   . ARG B 2 33  ? 186.502 184.696 204.218 1.00 41.23  ? 37  ARG F NH1   1 
ATOM   6202 N NH2   . ARG B 2 33  ? 185.090 182.965 203.723 1.00 41.23  ? 37  ARG F NH2   1 
ATOM   6203 N N     . PRO B 2 34  ? 184.968 187.262 211.492 1.00 39.85  ? 38  PRO F N     1 
ATOM   6204 C CA    . PRO B 2 34  ? 185.371 187.809 212.787 1.00 39.85  ? 38  PRO F CA    1 
ATOM   6205 C C     . PRO B 2 34  ? 186.810 187.456 213.099 1.00 39.85  ? 38  PRO F C     1 
ATOM   6206 O O     . PRO B 2 34  ? 187.271 186.354 212.808 1.00 39.85  ? 38  PRO F O     1 
ATOM   6207 C CB    . PRO B 2 34  ? 184.400 187.145 213.763 1.00 39.85  ? 38  PRO F CB    1 
ATOM   6208 C CG    . PRO B 2 34  ? 183.994 185.904 213.088 1.00 39.85  ? 38  PRO F CG    1 
ATOM   6209 C CD    . PRO B 2 34  ? 183.971 186.194 211.632 1.00 39.85  ? 38  PRO F CD    1 
ATOM   6210 N N     . ARG B 2 35  ? 187.527 188.405 213.682 1.00 39.71  ? 39  ARG F N     1 
ATOM   6211 C CA    . ARG B 2 35  ? 188.931 188.200 213.988 1.00 39.71  ? 39  ARG F CA    1 
ATOM   6212 C C     . ARG B 2 35  ? 189.240 188.177 215.476 1.00 39.71  ? 39  ARG F C     1 
ATOM   6213 O O     . ARG B 2 35  ? 190.395 187.960 215.846 1.00 39.71  ? 39  ARG F O     1 
ATOM   6214 C CB    . ARG B 2 35  ? 189.773 189.270 213.308 1.00 39.71  ? 39  ARG F CB    1 
ATOM   6215 C CG    . ARG B 2 35  ? 189.331 190.663 213.567 1.00 39.71  ? 39  ARG F CG    1 
ATOM   6216 C CD    . ARG B 2 35  ? 190.489 191.567 213.336 1.00 39.71  ? 39  ARG F CD    1 
ATOM   6217 N NE    . ARG B 2 35  ? 190.114 192.962 213.369 1.00 39.71  ? 39  ARG F NE    1 
ATOM   6218 C CZ    . ARG B 2 35  ? 190.929 193.918 213.776 1.00 39.71  ? 39  ARG F CZ    1 
ATOM   6219 N NH1   . ARG B 2 35  ? 192.141 193.605 214.185 1.00 39.71  ? 39  ARG F NH1   1 
ATOM   6220 N NH2   . ARG B 2 35  ? 190.535 195.180 213.783 1.00 39.71  ? 39  ARG F NH2   1 
ATOM   6221 N N     . HIS B 2 36  ? 188.254 188.397 216.334 1.00 40.96  ? 40  HIS F N     1 
ATOM   6222 C CA    . HIS B 2 36  ? 188.413 188.273 217.769 1.00 40.96  ? 40  HIS F CA    1 
ATOM   6223 C C     . HIS B 2 36  ? 187.769 186.972 218.223 1.00 40.96  ? 40  HIS F C     1 
ATOM   6224 O O     . HIS B 2 36  ? 187.266 186.193 217.415 1.00 40.96  ? 40  HIS F O     1 
ATOM   6225 C CB    . HIS B 2 36  ? 187.827 189.493 218.464 1.00 40.96  ? 40  HIS F CB    1 
ATOM   6226 C CG    . HIS B 2 36  ? 188.495 190.771 218.074 1.00 40.96  ? 40  HIS F CG    1 
ATOM   6227 N ND1   . HIS B 2 36  ? 189.844 190.985 218.247 1.00 40.96  ? 40  HIS F ND1   1 
ATOM   6228 C CD2   . HIS B 2 36  ? 188.006 191.899 217.513 1.00 40.96  ? 40  HIS F CD2   1 
ATOM   6229 C CE1   . HIS B 2 36  ? 190.155 192.192 217.817 1.00 40.96  ? 40  HIS F CE1   1 
ATOM   6230 N NE2   . HIS B 2 36  ? 189.058 192.769 217.367 1.00 40.96  ? 40  HIS F NE2   1 
ATOM   6231 N N     . GLN B 2 37  ? 187.785 186.720 219.531 1.00 47.00  ? 41  GLN F N     1 
ATOM   6232 C CA    . GLN B 2 37  ? 187.499 185.360 219.973 1.00 47.00  ? 41  GLN F CA    1 
ATOM   6233 C C     . GLN B 2 37  ? 186.021 185.103 220.241 1.00 47.00  ? 41  GLN F C     1 
ATOM   6234 O O     . GLN B 2 37  ? 185.488 184.080 219.806 1.00 47.00  ? 41  GLN F O     1 
ATOM   6235 C CB    . GLN B 2 37  ? 188.326 185.013 221.210 1.00 47.00  ? 41  GLN F CB    1 
ATOM   6236 C CG    . GLN B 2 37  ? 188.399 186.081 222.267 1.00 47.00  ? 41  GLN F CG    1 
ATOM   6237 C CD    . GLN B 2 37  ? 188.909 185.525 223.583 1.00 47.00  ? 41  GLN F CD    1 
ATOM   6238 O OE1   . GLN B 2 37  ? 188.708 184.350 223.890 1.00 47.00  ? 41  GLN F OE1   1 
ATOM   6239 N NE2   . GLN B 2 37  ? 189.581 186.362 224.362 1.00 47.00  ? 41  GLN F NE2   1 
ATOM   6240 N N     . GLY B 2 38  ? 185.349 185.982 220.971 1.00 45.03  ? 42  GLY F N     1 
ATOM   6241 C CA    . GLY B 2 38  ? 183.930 185.783 221.188 1.00 45.03  ? 42  GLY F CA    1 
ATOM   6242 C C     . GLY B 2 38  ? 183.625 185.090 222.493 1.00 45.03  ? 42  GLY F C     1 
ATOM   6243 O O     . GLY B 2 38  ? 183.832 183.885 222.625 1.00 45.03  ? 42  GLY F O     1 
ATOM   6244 N N     . VAL B 2 39  ? 183.117 185.842 223.463 1.00 43.04  ? 43  VAL F N     1 
ATOM   6245 C CA    . VAL B 2 39  ? 182.972 185.370 224.827 1.00 43.04  ? 43  VAL F CA    1 
ATOM   6246 C C     . VAL B 2 39  ? 181.517 185.100 225.187 1.00 43.04  ? 43  VAL F C     1 
ATOM   6247 O O     . VAL B 2 39  ? 181.223 184.126 225.879 1.00 43.04  ? 43  VAL F O     1 
ATOM   6248 C CB    . VAL B 2 39  ? 183.601 186.378 225.803 1.00 43.04  ? 43  VAL F CB    1 
ATOM   6249 C CG1   . VAL B 2 39  ? 185.095 186.354 225.665 1.00 43.04  ? 43  VAL F CG1   1 
ATOM   6250 C CG2   . VAL B 2 39  ? 183.083 187.756 225.516 1.00 43.04  ? 43  VAL F CG2   1 
ATOM   6251 N N     . MET B 2 40  ? 180.599 185.948 224.745 1.00 44.92  ? 44  MET F N     1 
ATOM   6252 C CA    . MET B 2 40  ? 179.193 185.737 225.039 1.00 44.92  ? 44  MET F CA    1 
ATOM   6253 C C     . MET B 2 40  ? 178.760 184.403 224.468 1.00 44.92  ? 44  MET F C     1 
ATOM   6254 O O     . MET B 2 40  ? 178.730 184.222 223.249 1.00 44.92  ? 44  MET F O     1 
ATOM   6255 C CB    . MET B 2 40  ? 178.360 186.860 224.438 1.00 44.92  ? 44  MET F CB    1 
ATOM   6256 C CG    . MET B 2 40  ? 178.685 188.236 224.955 1.00 44.92  ? 44  MET F CG    1 
ATOM   6257 S SD    . MET B 2 40  ? 178.186 188.595 226.623 1.00 44.92  ? 44  MET F SD    1 
ATOM   6258 C CE    . MET B 2 40  ? 176.438 188.776 226.350 1.00 44.92  ? 44  MET F CE    1 
ATOM   6259 N N     . VAL B 2 41  ? 178.429 183.468 225.343 1.00 45.11  ? 45  VAL F N     1 
ATOM   6260 C CA    . VAL B 2 41  ? 178.006 182.136 224.944 1.00 45.11  ? 45  VAL F CA    1 
ATOM   6261 C C     . VAL B 2 41  ? 176.500 182.155 224.797 1.00 45.11  ? 45  VAL F C     1 
ATOM   6262 O O     . VAL B 2 41  ? 175.793 182.679 225.663 1.00 45.11  ? 45  VAL F O     1 
ATOM   6263 C CB    . VAL B 2 41  ? 178.438 181.083 225.973 1.00 45.11  ? 45  VAL F CB    1 
ATOM   6264 C CG1   . VAL B 2 41  ? 177.671 179.794 225.765 1.00 45.11  ? 45  VAL F CG1   1 
ATOM   6265 C CG2   . VAL B 2 41  ? 179.926 180.853 225.886 1.00 45.11  ? 45  VAL F CG2   1 
ATOM   6266 N N     . GLY B 2 42  ? 176.002 181.609 223.692 1.00 50.98  ? 46  GLY F N     1 
ATOM   6267 C CA    . GLY B 2 42  ? 174.585 181.470 223.457 1.00 50.98  ? 46  GLY F CA    1 
ATOM   6268 C C     . GLY B 2 42  ? 174.048 182.412 222.404 1.00 50.98  ? 46  GLY F C     1 
ATOM   6269 O O     . GLY B 2 42  ? 173.007 182.127 221.806 1.00 50.98  ? 46  GLY F O     1 
ATOM   6270 N N     . MET B 2 43  ? 174.726 183.529 222.167 1.00 53.06  ? 47  MET F N     1 
ATOM   6271 C CA    . MET B 2 43  ? 174.244 184.440 221.145 1.00 53.06  ? 47  MET F CA    1 
ATOM   6272 C C     . MET B 2 43  ? 174.411 183.871 219.746 1.00 53.06  ? 47  MET F C     1 
ATOM   6273 O O     . MET B 2 43  ? 173.820 184.402 218.799 1.00 53.06  ? 47  MET F O     1 
ATOM   6274 C CB    . MET B 2 43  ? 174.955 185.776 221.257 1.00 53.06  ? 47  MET F CB    1 
ATOM   6275 C CG    . MET B 2 43  ? 176.371 185.736 220.828 1.00 53.06  ? 47  MET F CG    1 
ATOM   6276 S SD    . MET B 2 43  ? 177.031 187.412 220.856 1.00 53.06  ? 47  MET F SD    1 
ATOM   6277 C CE    . MET B 2 43  ? 175.653 188.324 220.169 1.00 53.06  ? 47  MET F CE    1 
ATOM   6278 N N     . GLY B 2 44  ? 175.192 182.805 219.594 1.00 53.30  ? 48  GLY F N     1 
ATOM   6279 C CA    . GLY B 2 44  ? 175.290 182.113 218.327 1.00 53.30  ? 48  GLY F CA    1 
ATOM   6280 C C     . GLY B 2 44  ? 175.853 182.969 217.215 1.00 53.30  ? 48  GLY F C     1 
ATOM   6281 O O     . GLY B 2 44  ? 175.134 183.324 216.279 1.00 53.30  ? 48  GLY F O     1 
ATOM   6282 N N     . GLN B 2 45  ? 177.128 183.327 217.313 1.00 51.49  ? 49  GLN F N     1 
ATOM   6283 C CA    . GLN B 2 45  ? 177.760 184.061 216.233 1.00 51.49  ? 49  GLN F CA    1 
ATOM   6284 C C     . GLN B 2 45  ? 177.877 183.179 214.994 1.00 51.49  ? 49  GLN F C     1 
ATOM   6285 O O     . GLN B 2 45  ? 178.048 181.962 215.082 1.00 51.49  ? 49  GLN F O     1 
ATOM   6286 C CB    . GLN B 2 45  ? 179.153 184.551 216.637 1.00 51.49  ? 49  GLN F CB    1 
ATOM   6287 C CG    . GLN B 2 45  ? 179.223 185.614 217.738 1.00 51.49  ? 49  GLN F CG    1 
ATOM   6288 C CD    . GLN B 2 45  ? 179.506 185.047 219.115 1.00 51.49  ? 49  GLN F CD    1 
ATOM   6289 O OE1   . GLN B 2 45  ? 179.888 183.884 219.253 1.00 51.49  ? 49  GLN F OE1   1 
ATOM   6290 N NE2   . GLN B 2 45  ? 179.386 185.885 220.136 1.00 51.49  ? 49  GLN F NE2   1 
ATOM   6291 N N     . LYS B 2 46  ? 177.773 183.809 213.830 1.00 48.84  ? 50  LYS F N     1 
ATOM   6292 C CA    . LYS B 2 46  ? 178.057 183.156 212.565 1.00 48.84  ? 50  LYS F CA    1 
ATOM   6293 C C     . LYS B 2 46  ? 179.503 183.413 212.168 1.00 48.84  ? 50  LYS F C     1 
ATOM   6294 O O     . LYS B 2 46  ? 180.215 184.190 212.800 1.00 48.84  ? 50  LYS F O     1 
ATOM   6295 C CB    . LYS B 2 46  ? 177.120 183.658 211.482 1.00 48.84  ? 50  LYS F CB    1 
ATOM   6296 C CG    . LYS B 2 46  ? 177.191 185.141 211.292 1.00 48.84  ? 50  LYS F CG    1 
ATOM   6297 C CD    . LYS B 2 46  ? 176.090 185.590 210.382 1.00 48.84  ? 50  LYS F CD    1 
ATOM   6298 C CE    . LYS B 2 46  ? 174.757 185.101 210.894 1.00 48.84  ? 50  LYS F CE    1 
ATOM   6299 N NZ    . LYS B 2 46  ? 174.466 185.668 212.235 1.00 48.84  ? 50  LYS F NZ    1 
ATOM   6300 N N     . ASP B 2 47  ? 179.935 182.761 211.095 1.00 47.82  ? 51  ASP F N     1 
ATOM   6301 C CA    . ASP B 2 47  ? 181.348 182.738 210.753 1.00 47.82  ? 51  ASP F CA    1 
ATOM   6302 C C     . ASP B 2 47  ? 181.727 183.687 209.631 1.00 47.82  ? 51  ASP F C     1 
ATOM   6303 O O     . ASP B 2 47  ? 182.918 183.938 209.436 1.00 47.82  ? 51  ASP F O     1 
ATOM   6304 C CB    . ASP B 2 47  ? 181.766 181.328 210.356 1.00 47.82  ? 51  ASP F CB    1 
ATOM   6305 C CG    . ASP B 2 47  ? 180.956 180.801 209.209 1.00 47.82  ? 51  ASP F CG    1 
ATOM   6306 O OD1   . ASP B 2 47  ? 179.772 181.181 209.109 1.00 47.82  ? 51  ASP F OD1   1 
ATOM   6307 O OD2   . ASP B 2 47  ? 181.498 180.018 208.405 1.00 47.82  ? 51  ASP F OD2   1 
ATOM   6308 N N     . SER B 2 48  ? 180.765 184.210 208.884 1.00 43.34  ? 52  SER F N     1 
ATOM   6309 C CA    . SER B 2 48  ? 181.094 185.088 207.770 1.00 43.34  ? 52  SER F CA    1 
ATOM   6310 C C     . SER B 2 48  ? 179.894 185.959 207.473 1.00 43.34  ? 52  SER F C     1 
ATOM   6311 O O     . SER B 2 48  ? 178.802 185.443 207.240 1.00 43.34  ? 52  SER F O     1 
ATOM   6312 C CB    . SER B 2 48  ? 181.479 184.287 206.548 1.00 43.34  ? 52  SER F CB    1 
ATOM   6313 O OG    . SER B 2 48  ? 180.322 183.840 205.876 1.00 43.34  ? 52  SER F OG    1 
ATOM   6314 N N     . TYR B 2 49  ? 180.097 187.264 207.480 1.00 43.03  ? 53  TYR F N     1 
ATOM   6315 C CA    . TYR B 2 49  ? 179.069 188.217 207.106 1.00 43.03  ? 53  TYR F CA    1 
ATOM   6316 C C     . TYR B 2 49  ? 179.376 188.731 205.715 1.00 43.03  ? 53  TYR F C     1 
ATOM   6317 O O     . TYR B 2 49  ? 180.521 189.066 205.414 1.00 43.03  ? 53  TYR F O     1 
ATOM   6318 C CB    . TYR B 2 49  ? 179.014 189.381 208.086 1.00 43.03  ? 53  TYR F CB    1 
ATOM   6319 C CG    . TYR B 2 49  ? 178.868 188.973 209.522 1.00 43.03  ? 53  TYR F CG    1 
ATOM   6320 C CD1   . TYR B 2 49  ? 177.646 189.042 210.152 1.00 43.03  ? 53  TYR F CD1   1 
ATOM   6321 C CD2   . TYR B 2 49  ? 179.954 188.533 210.252 1.00 43.03  ? 53  TYR F CD2   1 
ATOM   6322 C CE1   . TYR B 2 49  ? 177.508 188.683 211.455 1.00 43.03  ? 53  TYR F CE1   1 
ATOM   6323 C CE2   . TYR B 2 49  ? 179.822 188.171 211.557 1.00 43.03  ? 53  TYR F CE2   1 
ATOM   6324 C CZ    . TYR B 2 49  ? 178.596 188.248 212.155 1.00 43.03  ? 53  TYR F CZ    1 
ATOM   6325 O OH    . TYR B 2 49  ? 178.452 187.886 213.469 1.00 43.03  ? 53  TYR F OH    1 
ATOM   6326 N N     . VAL B 2 50  ? 178.360 188.796 204.877 1.00 42.33  ? 54  VAL F N     1 
ATOM   6327 C CA    . VAL B 2 50  ? 178.529 189.192 203.492 1.00 42.33  ? 54  VAL F CA    1 
ATOM   6328 C C     . VAL B 2 50  ? 177.603 190.354 203.188 1.00 42.33  ? 54  VAL F C     1 
ATOM   6329 O O     . VAL B 2 50  ? 176.440 190.356 203.593 1.00 42.33  ? 54  VAL F O     1 
ATOM   6330 C CB    . VAL B 2 50  ? 178.275 188.007 202.543 1.00 42.33  ? 54  VAL F CB    1 
ATOM   6331 C CG1   . VAL B 2 50  ? 176.963 187.370 202.843 1.00 42.33  ? 54  VAL F CG1   1 
ATOM   6332 C CG2   . VAL B 2 50  ? 178.256 188.490 201.143 1.00 42.33  ? 54  VAL F CG2   1 
ATOM   6333 N N     . GLY B 2 51  ? 178.129 191.358 202.511 1.00 41.11  ? 55  GLY F N     1 
ATOM   6334 C CA    . GLY B 2 51  ? 177.294 192.425 202.013 1.00 41.11  ? 55  GLY F CA    1 
ATOM   6335 C C     . GLY B 2 51  ? 177.247 193.666 202.867 1.00 41.11  ? 55  GLY F C     1 
ATOM   6336 O O     . GLY B 2 51  ? 178.269 194.145 203.350 1.00 41.11  ? 55  GLY F O     1 
ATOM   6337 N N     . ASP B 2 52  ? 176.045 194.206 203.034 1.00 45.62  ? 56  ASP F N     1 
ATOM   6338 C CA    . ASP B 2 52  ? 175.842 195.426 203.796 1.00 45.62  ? 56  ASP F CA    1 
ATOM   6339 C C     . ASP B 2 52  ? 175.847 195.179 205.289 1.00 45.62  ? 56  ASP F C     1 
ATOM   6340 O O     . ASP B 2 52  ? 175.960 196.128 206.066 1.00 45.62  ? 56  ASP F O     1 
ATOM   6341 C CB    . ASP B 2 52  ? 174.520 196.070 203.396 1.00 45.62  ? 56  ASP F CB    1 
ATOM   6342 C CG    . ASP B 2 52  ? 174.602 197.567 203.351 1.00 45.62  ? 56  ASP F CG    1 
ATOM   6343 O OD1   . ASP B 2 52  ? 175.322 198.140 204.192 1.00 45.62  ? 56  ASP F OD1   1 
ATOM   6344 O OD2   . ASP B 2 52  ? 173.949 198.172 202.475 1.00 45.62  ? 56  ASP F OD2   1 
ATOM   6345 N N     . GLU B 2 53  ? 175.707 193.926 205.699 1.00 45.46  ? 57  GLU F N     1 
ATOM   6346 C CA    . GLU B 2 53  ? 175.801 193.585 207.107 1.00 45.46  ? 57  GLU F CA    1 
ATOM   6347 C C     . GLU B 2 53  ? 177.239 193.663 207.589 1.00 45.46  ? 57  GLU F C     1 
ATOM   6348 O O     . GLU B 2 53  ? 177.508 194.145 208.696 1.00 45.46  ? 57  GLU F O     1 
ATOM   6349 C CB    . GLU B 2 53  ? 175.228 192.192 207.304 1.00 45.46  ? 57  GLU F CB    1 
ATOM   6350 C CG    . GLU B 2 53  ? 175.395 191.605 208.661 1.00 45.46  ? 57  GLU F CG    1 
ATOM   6351 C CD    . GLU B 2 53  ? 174.743 190.251 208.730 1.00 45.46  ? 57  GLU F CD    1 
ATOM   6352 O OE1   . GLU B 2 53  ? 174.302 189.771 207.666 1.00 45.46  ? 57  GLU F OE1   1 
ATOM   6353 O OE2   . GLU B 2 53  ? 174.668 189.668 209.830 1.00 45.46  ? 57  GLU F OE2   1 
ATOM   6354 N N     . ALA B 2 54  ? 178.177 193.208 206.759 1.00 42.59  ? 58  ALA F N     1 
ATOM   6355 C CA    . ALA B 2 54  ? 179.589 193.286 207.091 1.00 42.59  ? 58  ALA F CA    1 
ATOM   6356 C C     . ALA B 2 54  ? 180.053 194.713 207.291 1.00 42.59  ? 58  ALA F C     1 
ATOM   6357 O O     . ALA B 2 54  ? 181.083 194.929 207.926 1.00 42.59  ? 58  ALA F O     1 
ATOM   6358 C CB    . ALA B 2 54  ? 180.421 192.623 206.002 1.00 42.59  ? 58  ALA F CB    1 
ATOM   6359 N N     . GLN B 2 55  ? 179.335 195.690 206.756 1.00 42.35  ? 59  GLN F N     1 
ATOM   6360 C CA    . GLN B 2 55  ? 179.684 197.078 207.013 1.00 42.35  ? 59  GLN F CA    1 
ATOM   6361 C C     . GLN B 2 55  ? 179.143 197.564 208.345 1.00 42.35  ? 59  GLN F C     1 
ATOM   6362 O O     . GLN B 2 55  ? 179.665 198.531 208.903 1.00 42.35  ? 59  GLN F O     1 
ATOM   6363 C CB    . GLN B 2 55  ? 179.164 197.962 205.894 1.00 42.35  ? 59  GLN F CB    1 
ATOM   6364 C CG    . GLN B 2 55  ? 179.880 197.768 204.605 1.00 42.35  ? 59  GLN F CG    1 
ATOM   6365 C CD    . GLN B 2 55  ? 180.942 198.794 204.397 1.00 42.35  ? 59  GLN F CD    1 
ATOM   6366 O OE1   . GLN B 2 55  ? 182.123 198.518 204.553 1.00 42.35  ? 59  GLN F OE1   1 
ATOM   6367 N NE2   . GLN B 2 55  ? 180.532 199.998 204.047 1.00 42.35  ? 59  GLN F NE2   1 
ATOM   6368 N N     . SER B 2 56  ? 178.084 196.941 208.853 1.00 42.87  ? 60  SER F N     1 
ATOM   6369 C CA    . SER B 2 56  ? 177.617 197.274 210.192 1.00 42.87  ? 60  SER F CA    1 
ATOM   6370 C C     . SER B 2 56  ? 178.516 196.645 211.243 1.00 42.87  ? 60  SER F C     1 
ATOM   6371 O O     . SER B 2 56  ? 178.959 197.315 212.179 1.00 42.87  ? 60  SER F O     1 
ATOM   6372 C CB    . SER B 2 56  ? 176.177 196.815 210.371 1.00 42.87  ? 60  SER F CB    1 
ATOM   6373 O OG    . SER B 2 56  ? 175.315 197.540 209.522 1.00 42.87  ? 60  SER F OG    1 
ATOM   6374 N N     . LYS B 2 57  ? 178.823 195.362 211.089 1.00 40.67  ? 61  LYS F N     1 
ATOM   6375 C CA    . LYS B 2 57  ? 179.744 194.695 211.993 1.00 40.67  ? 61  LYS F CA    1 
ATOM   6376 C C     . LYS B 2 57  ? 181.182 194.976 211.650 1.00 40.67  ? 61  LYS F C     1 
ATOM   6377 O O     . LYS B 2 57  ? 182.064 194.220 212.045 1.00 40.67  ? 61  LYS F O     1 
ATOM   6378 C CB    . LYS B 2 57  ? 179.511 193.188 211.980 1.00 40.67  ? 61  LYS F CB    1 
ATOM   6379 C CG    . LYS B 2 57  ? 178.078 192.771 212.096 1.00 40.67  ? 61  LYS F CG    1 
ATOM   6380 C CD    . LYS B 2 57  ? 177.522 193.139 213.433 1.00 40.67  ? 61  LYS F CD    1 
ATOM   6381 C CE    . LYS B 2 57  ? 176.239 192.393 213.685 1.00 40.67  ? 61  LYS F CE    1 
ATOM   6382 N NZ    . LYS B 2 57  ? 176.491 190.935 213.676 1.00 40.67  ? 61  LYS F NZ    1 
ATOM   6383 N N     . ARG B 2 58  ? 181.423 196.055 210.916 1.00 39.43  ? 62  ARG F N     1 
ATOM   6384 C CA    . ARG B 2 58  ? 182.728 196.318 210.330 1.00 39.43  ? 62  ARG F CA    1 
ATOM   6385 C C     . ARG B 2 58  ? 183.825 196.411 211.373 1.00 39.43  ? 62  ARG F C     1 
ATOM   6386 O O     . ARG B 2 58  ? 184.984 196.120 211.074 1.00 39.43  ? 62  ARG F O     1 
ATOM   6387 C CB    . ARG B 2 58  ? 182.640 197.607 209.522 1.00 39.43  ? 62  ARG F CB    1 
ATOM   6388 C CG    . ARG B 2 58  ? 183.929 198.227 209.156 1.00 39.43  ? 62  ARG F CG    1 
ATOM   6389 C CD    . ARG B 2 58  ? 183.681 199.456 208.333 1.00 39.43  ? 62  ARG F CD    1 
ATOM   6390 N NE    . ARG B 2 58  ? 182.941 200.463 209.066 1.00 39.43  ? 62  ARG F NE    1 
ATOM   6391 C CZ    . ARG B 2 58  ? 182.505 201.589 208.525 1.00 39.43  ? 62  ARG F CZ    1 
ATOM   6392 N NH1   . ARG B 2 58  ? 182.728 201.836 207.251 1.00 39.43  ? 62  ARG F NH1   1 
ATOM   6393 N NH2   . ARG B 2 58  ? 181.842 202.468 209.253 1.00 39.43  ? 62  ARG F NH2   1 
ATOM   6394 N N     . GLY B 2 59  ? 183.489 196.792 212.599 1.00 37.59  ? 63  GLY F N     1 
ATOM   6395 C CA    . GLY B 2 59  ? 184.516 197.048 213.587 1.00 37.59  ? 63  GLY F CA    1 
ATOM   6396 C C     . GLY B 2 59  ? 185.211 195.818 214.122 1.00 37.59  ? 63  GLY F C     1 
ATOM   6397 O O     . GLY B 2 59  ? 186.283 195.953 214.716 1.00 37.59  ? 63  GLY F O     1 
ATOM   6398 N N     . ILE B 2 60  ? 184.653 194.631 213.921 1.00 36.99  ? 64  ILE F N     1 
ATOM   6399 C CA    . ILE B 2 60  ? 185.231 193.430 214.503 1.00 36.99  ? 64  ILE F CA    1 
ATOM   6400 C C     . ILE B 2 60  ? 185.509 192.380 213.439 1.00 36.99  ? 64  ILE F C     1 
ATOM   6401 O O     . ILE B 2 60  ? 185.744 191.213 213.760 1.00 36.99  ? 64  ILE F O     1 
ATOM   6402 C CB    . ILE B 2 60  ? 184.311 192.850 215.583 1.00 36.99  ? 64  ILE F CB    1 
ATOM   6403 C CG1   . ILE B 2 60  ? 182.919 192.656 215.016 1.00 36.99  ? 64  ILE F CG1   1 
ATOM   6404 C CG2   . ILE B 2 60  ? 184.265 193.751 216.776 1.00 36.99  ? 64  ILE F CG2   1 
ATOM   6405 C CD1   . ILE B 2 60  ? 182.097 191.725 215.798 1.00 36.99  ? 64  ILE F CD1   1 
ATOM   6406 N N     . LEU B 2 61  ? 185.495 192.778 212.174 1.00 37.66  ? 65  LEU F N     1 
ATOM   6407 C CA    . LEU B 2 61  ? 185.694 191.856 211.071 1.00 37.66  ? 65  LEU F CA    1 
ATOM   6408 C C     . LEU B 2 61  ? 186.932 192.246 210.282 1.00 37.66  ? 65  LEU F C     1 
ATOM   6409 O O     . LEU B 2 61  ? 187.451 193.353 210.411 1.00 37.66  ? 65  LEU F O     1 
ATOM   6410 C CB    . LEU B 2 61  ? 184.479 191.835 210.146 1.00 37.66  ? 65  LEU F CB    1 
ATOM   6411 C CG    . LEU B 2 61  ? 183.136 191.490 210.779 1.00 37.66  ? 65  LEU F CG    1 
ATOM   6412 C CD1   . LEU B 2 61  ? 182.025 191.732 209.808 1.00 37.66  ? 65  LEU F CD1   1 
ATOM   6413 C CD2   . LEU B 2 61  ? 183.103 190.068 211.214 1.00 37.66  ? 65  LEU F CD2   1 
ATOM   6414 N N     . THR B 2 62  ? 187.419 191.301 209.486 1.00 37.66  ? 66  THR F N     1 
ATOM   6415 C CA    . THR B 2 62  ? 188.402 191.554 208.439 1.00 37.66  ? 66  THR F CA    1 
ATOM   6416 C C     . THR B 2 62  ? 187.663 191.481 207.115 1.00 37.66  ? 66  THR F C     1 
ATOM   6417 O O     . THR B 2 62  ? 187.156 190.420 206.746 1.00 37.66  ? 66  THR F O     1 
ATOM   6418 C CB    . THR B 2 62  ? 189.536 190.536 208.460 1.00 37.66  ? 66  THR F CB    1 
ATOM   6419 O OG1   . THR B 2 62  ? 188.990 189.222 208.333 1.00 37.66  ? 66  THR F OG1   1 
ATOM   6420 C CG2   . THR B 2 62  ? 190.307 190.619 209.738 1.00 37.66  ? 66  THR F CG2   1 
ATOM   6421 N N     . LEU B 2 63  ? 187.601 192.592 206.404 1.00 37.16  ? 67  LEU F N     1 
ATOM   6422 C CA    . LEU B 2 63  ? 186.840 192.664 205.171 1.00 37.16  ? 67  LEU F CA    1 
ATOM   6423 C C     . LEU B 2 63  ? 187.704 192.246 203.994 1.00 37.16  ? 67  LEU F C     1 
ATOM   6424 O O     . LEU B 2 63  ? 188.781 192.804 203.777 1.00 37.16  ? 67  LEU F O     1 
ATOM   6425 C CB    . LEU B 2 63  ? 186.308 194.076 204.963 1.00 37.16  ? 67  LEU F CB    1 
ATOM   6426 C CG    . LEU B 2 63  ? 185.558 194.635 206.157 1.00 37.16  ? 67  LEU F CG    1 
ATOM   6427 C CD1   . LEU B 2 63  ? 185.096 196.014 205.841 1.00 37.16  ? 67  LEU F CD1   1 
ATOM   6428 C CD2   . LEU B 2 63  ? 184.395 193.755 206.482 1.00 37.16  ? 67  LEU F CD2   1 
ATOM   6429 N N     . LYS B 2 64  ? 187.230 191.266 203.238 1.00 38.37  ? 68  LYS F N     1 
ATOM   6430 C CA    . LYS B 2 64  ? 187.897 190.798 202.036 1.00 38.37  ? 68  LYS F CA    1 
ATOM   6431 C C     . LYS B 2 64  ? 187.063 191.164 200.825 1.00 38.37  ? 68  LYS F C     1 
ATOM   6432 O O     . LYS B 2 64  ? 185.837 191.079 200.862 1.00 38.37  ? 68  LYS F O     1 
ATOM   6433 C CB    . LYS B 2 64  ? 188.099 189.292 202.058 1.00 38.37  ? 68  LYS F CB    1 
ATOM   6434 C CG    . LYS B 2 64  ? 189.145 188.815 203.022 1.00 38.37  ? 68  LYS F CG    1 
ATOM   6435 C CD    . LYS B 2 64  ? 190.456 189.502 202.760 1.00 38.37  ? 68  LYS F CD    1 
ATOM   6436 C CE    . LYS B 2 64  ? 191.565 188.924 203.614 1.00 38.37  ? 68  LYS F CE    1 
ATOM   6437 N NZ    . LYS B 2 64  ? 192.791 189.758 203.508 1.00 38.37  ? 68  LYS F NZ    1 
ATOM   6438 N N     . TYR B 2 65  ? 187.727 191.581 199.761 1.00 39.75  ? 69  TYR F N     1 
ATOM   6439 C CA    . TYR B 2 65  ? 187.072 191.730 198.475 1.00 39.75  ? 69  TYR F CA    1 
ATOM   6440 C C     . TYR B 2 65  ? 187.339 190.491 197.640 1.00 39.75  ? 69  TYR F C     1 
ATOM   6441 O O     . TYR B 2 65  ? 188.504 190.169 197.393 1.00 39.75  ? 69  TYR F O     1 
ATOM   6442 C CB    . TYR B 2 65  ? 187.580 192.950 197.755 1.00 39.75  ? 69  TYR F CB    1 
ATOM   6443 C CG    . TYR B 2 65  ? 187.002 194.238 198.251 1.00 39.75  ? 69  TYR F CG    1 
ATOM   6444 C CD1   . TYR B 2 65  ? 185.812 194.715 197.755 1.00 39.75  ? 69  TYR F CD1   1 
ATOM   6445 C CD2   . TYR B 2 65  ? 187.657 194.987 199.199 1.00 39.75  ? 69  TYR F CD2   1 
ATOM   6446 C CE1   . TYR B 2 65  ? 185.289 195.887 198.197 1.00 39.75  ? 69  TYR F CE1   1 
ATOM   6447 C CE2   . TYR B 2 65  ? 187.139 196.159 199.643 1.00 39.75  ? 69  TYR F CE2   1 
ATOM   6448 C CZ    . TYR B 2 65  ? 185.957 196.604 199.140 1.00 39.75  ? 69  TYR F CZ    1 
ATOM   6449 O OH    . TYR B 2 65  ? 185.433 197.787 199.585 1.00 39.75  ? 69  TYR F OH    1 
ATOM   6450 N N     . PRO B 2 66  ? 186.314 189.773 197.195 1.00 41.41  ? 70  PRO F N     1 
ATOM   6451 C CA    . PRO B 2 66  ? 186.558 188.539 196.446 1.00 41.41  ? 70  PRO F CA    1 
ATOM   6452 C C     . PRO B 2 66  ? 187.033 188.765 195.029 1.00 41.41  ? 70  PRO F C     1 
ATOM   6453 O O     . PRO B 2 66  ? 187.304 187.790 194.325 1.00 41.41  ? 70  PRO F O     1 
ATOM   6454 C CB    . PRO B 2 66  ? 185.196 187.853 196.464 1.00 41.41  ? 70  PRO F CB    1 
ATOM   6455 C CG    . PRO B 2 66  ? 184.247 188.953 196.614 1.00 41.41  ? 70  PRO F CG    1 
ATOM   6456 C CD    . PRO B 2 66  ? 184.891 189.971 197.471 1.00 41.41  ? 70  PRO F CD    1 
ATOM   6457 N N     . ILE B 2 67  ? 187.120 190.006 194.578 1.00 42.19  ? 71  ILE F N     1 
ATOM   6458 C CA    . ILE B 2 67  ? 187.416 190.333 193.194 1.00 42.19  ? 71  ILE F CA    1 
ATOM   6459 C C     . ILE B 2 67  ? 188.376 191.513 193.165 1.00 42.19  ? 71  ILE F C     1 
ATOM   6460 O O     . ILE B 2 67  ? 188.103 192.559 193.757 1.00 42.19  ? 71  ILE F O     1 
ATOM   6461 C CB    . ILE B 2 67  ? 186.103 190.622 192.448 1.00 42.19  ? 71  ILE F CB    1 
ATOM   6462 C CG1   . ILE B 2 67  ? 186.343 191.006 191.010 1.00 42.19  ? 71  ILE F CG1   1 
ATOM   6463 C CG2   . ILE B 2 67  ? 185.298 191.647 193.166 1.00 42.19  ? 71  ILE F CG2   1 
ATOM   6464 C CD1   . ILE B 2 67  ? 185.086 191.000 190.242 1.00 42.19  ? 71  ILE F CD1   1 
ATOM   6465 N N     . GLU B 2 68  ? 189.517 191.341 192.500 1.00 46.29  ? 72  GLU F N     1 
ATOM   6466 C CA    . GLU B 2 68  ? 190.628 192.271 192.677 1.00 46.29  ? 72  GLU F CA    1 
ATOM   6467 C C     . GLU B 2 68  ? 190.691 193.363 191.616 1.00 46.29  ? 72  GLU F C     1 
ATOM   6468 O O     . GLU B 2 68  ? 190.496 194.539 191.931 1.00 46.29  ? 72  GLU F O     1 
ATOM   6469 C CB    . GLU B 2 68  ? 191.946 191.497 192.715 1.00 46.29  ? 72  GLU F CB    1 
ATOM   6470 C CG    . GLU B 2 68  ? 193.169 192.388 192.735 1.00 46.29  ? 72  GLU F CG    1 
ATOM   6471 C CD    . GLU B 2 68  ? 193.189 193.334 193.919 1.00 46.29  ? 72  GLU F CD    1 
ATOM   6472 O OE1   . GLU B 2 68  ? 192.615 192.986 194.971 1.00 46.29  ? 72  GLU F OE1   1 
ATOM   6473 O OE2   . GLU B 2 68  ? 193.777 194.427 193.799 1.00 46.29  ? 72  GLU F OE2   1 
ATOM   6474 N N     . HIS B 2 69  ? 190.954 193.007 190.362 1.00 44.12  ? 73  HIS F N     1 
ATOM   6475 C CA    . HIS B 2 69  ? 190.906 193.957 189.249 1.00 44.12  ? 73  HIS F CA    1 
ATOM   6476 C C     . HIS B 2 69  ? 190.048 193.297 188.198 1.00 44.12  ? 73  HIS F C     1 
ATOM   6477 O O     . HIS B 2 69  ? 190.570 192.716 187.253 1.00 44.12  ? 73  HIS F O     1 
ATOM   6478 C CB    . HIS B 2 69  ? 192.275 194.259 188.688 1.00 44.12  ? 73  HIS F CB    1 
ATOM   6479 C CG    . HIS B 2 69  ? 193.157 195.064 189.583 1.00 44.12  ? 73  HIS F CG    1 
ATOM   6480 N ND1   . HIS B 2 69  ? 194.264 194.532 190.201 1.00 44.12  ? 73  HIS F ND1   1 
ATOM   6481 C CD2   . HIS B 2 69  ? 193.134 196.373 189.916 1.00 44.12  ? 73  HIS F CD2   1 
ATOM   6482 C CE1   . HIS B 2 69  ? 194.869 195.472 190.901 1.00 44.12  ? 73  HIS F CE1   1 
ATOM   6483 N NE2   . HIS B 2 69  ? 194.202 196.599 190.746 1.00 44.12  ? 73  HIS F NE2   1 
ATOM   6484 N N     . GLY B 2 70  ? 188.738 193.373 188.347 1.00 44.12  ? 74  GLY F N     1 
ATOM   6485 C CA    . GLY B 2 70  ? 187.914 192.676 187.390 1.00 44.12  ? 74  GLY F CA    1 
ATOM   6486 C C     . GLY B 2 70  ? 187.918 191.181 187.617 1.00 44.12  ? 74  GLY F C     1 
ATOM   6487 O O     . GLY B 2 70  ? 186.889 190.523 187.477 1.00 44.12  ? 74  GLY F O     1 
ATOM   6488 N N     . ILE B 2 71  ? 189.080 190.636 187.947 1.00 42.04  ? 75  ILE F N     1 
ATOM   6489 C CA    . ILE B 2 71  ? 189.271 189.197 188.064 1.00 42.04  ? 75  ILE F CA    1 
ATOM   6490 C C     . ILE B 2 71  ? 188.811 188.724 189.433 1.00 42.04  ? 75  ILE F C     1 
ATOM   6491 O O     . ILE B 2 71  ? 189.078 189.370 190.448 1.00 42.04  ? 75  ILE F O     1 
ATOM   6492 C CB    . ILE B 2 71  ? 190.742 188.839 187.833 1.00 42.04  ? 75  ILE F CB    1 
ATOM   6493 C CG1   . ILE B 2 71  ? 191.250 189.552 186.589 1.00 42.04  ? 75  ILE F CG1   1 
ATOM   6494 C CG2   . ILE B 2 71  ? 190.903 187.351 187.716 1.00 42.04  ? 75  ILE F CG2   1 
ATOM   6495 C CD1   . ILE B 2 71  ? 192.722 189.811 186.602 1.00 42.04  ? 75  ILE F CD1   1 
ATOM   6496 N N     . ILE B 2 72  ? 188.141 187.583 189.468 1.00 42.62  ? 76  ILE F N     1 
ATOM   6497 C CA    . ILE B 2 72  ? 187.733 186.977 190.726 1.00 42.62  ? 76  ILE F CA    1 
ATOM   6498 C C     . ILE B 2 72  ? 188.873 186.130 191.264 1.00 42.62  ? 76  ILE F C     1 
ATOM   6499 O O     . ILE B 2 72  ? 189.383 185.243 190.576 1.00 42.62  ? 76  ILE F O     1 
ATOM   6500 C CB    . ILE B 2 72  ? 186.472 186.132 190.533 1.00 42.62  ? 76  ILE F CB    1 
ATOM   6501 C CG1   . ILE B 2 72  ? 185.322 187.011 190.069 1.00 42.62  ? 76  ILE F CG1   1 
ATOM   6502 C CG2   . ILE B 2 72  ? 186.111 185.469 191.811 1.00 42.62  ? 76  ILE F CG2   1 
ATOM   6503 C CD1   . ILE B 2 72  ? 184.143 186.241 189.589 1.00 42.62  ? 76  ILE F CD1   1 
ATOM   6504 N N     . THR B 2 73  ? 189.269 186.388 192.505 1.00 43.88  ? 77  THR F N     1 
ATOM   6505 C CA    . THR B 2 73  ? 190.372 185.669 193.112 1.00 43.88  ? 77  THR F CA    1 
ATOM   6506 C C     . THR B 2 73  ? 189.949 184.699 194.199 1.00 43.88  ? 77  THR F C     1 
ATOM   6507 O O     . THR B 2 73  ? 190.746 183.838 194.571 1.00 43.88  ? 77  THR F O     1 
ATOM   6508 C CB    . THR B 2 73  ? 191.381 186.651 193.708 1.00 43.88  ? 77  THR F CB    1 
ATOM   6509 O OG1   . THR B 2 73  ? 190.814 187.259 194.868 1.00 43.88  ? 77  THR F OG1   1 
ATOM   6510 C CG2   . THR B 2 73  ? 191.700 187.722 192.715 1.00 43.88  ? 77  THR F CG2   1 
ATOM   6511 N N     . ASN B 2 74  ? 188.732 184.811 194.715 1.00 46.13  ? 78  ASN F N     1 
ATOM   6512 C CA    . ASN B 2 74  ? 188.239 183.934 195.772 1.00 46.13  ? 78  ASN F CA    1 
ATOM   6513 C C     . ASN B 2 74  ? 186.876 183.404 195.345 1.00 46.13  ? 78  ASN F C     1 
ATOM   6514 O O     . ASN B 2 74  ? 185.863 184.101 195.453 1.00 46.13  ? 78  ASN F O     1 
ATOM   6515 C CB    . ASN B 2 74  ? 188.158 184.675 197.094 1.00 46.13  ? 78  ASN F CB    1 
ATOM   6516 C CG    . ASN B 2 74  ? 188.388 183.777 198.268 1.00 46.13  ? 78  ASN F CG    1 
ATOM   6517 O OD1   . ASN B 2 74  ? 188.338 182.560 198.149 1.00 46.13  ? 78  ASN F OD1   1 
ATOM   6518 N ND2   . ASN B 2 74  ? 188.644 184.372 199.419 1.00 46.13  ? 78  ASN F ND2   1 
ATOM   6519 N N     . TRP B 2 75  ? 186.843 182.165 194.875 1.00 46.25  ? 79  TRP F N     1 
ATOM   6520 C CA    . TRP B 2 75  ? 185.608 181.654 194.311 1.00 46.25  ? 79  TRP F CA    1 
ATOM   6521 C C     . TRP B 2 75  ? 184.593 181.287 195.377 1.00 46.25  ? 79  TRP F C     1 
ATOM   6522 O O     . TRP B 2 75  ? 183.388 181.415 195.144 1.00 46.25  ? 79  TRP F O     1 
ATOM   6523 C CB    . TRP B 2 75  ? 185.916 180.474 193.402 1.00 46.25  ? 79  TRP F CB    1 
ATOM   6524 C CG    . TRP B 2 75  ? 186.421 180.973 192.111 1.00 46.25  ? 79  TRP F CG    1 
ATOM   6525 C CD1   . TRP B 2 75  ? 187.702 180.967 191.677 1.00 46.25  ? 79  TRP F CD1   1 
ATOM   6526 C CD2   . TRP B 2 75  ? 185.655 181.623 191.099 1.00 46.25  ? 79  TRP F CD2   1 
ATOM   6527 N NE1   . TRP B 2 75  ? 187.782 181.553 190.445 1.00 46.25  ? 79  TRP F NE1   1 
ATOM   6528 C CE2   . TRP B 2 75  ? 186.533 181.964 190.070 1.00 46.25  ? 79  TRP F CE2   1 
ATOM   6529 C CE3   . TRP B 2 75  ? 184.304 181.938 190.962 1.00 46.25  ? 79  TRP F CE3   1 
ATOM   6530 C CZ2   . TRP B 2 75  ? 186.109 182.601 188.921 1.00 46.25  ? 79  TRP F CZ2   1 
ATOM   6531 C CZ3   . TRP B 2 75  ? 183.888 182.568 189.827 1.00 46.25  ? 79  TRP F CZ3   1 
ATOM   6532 C CH2   . TRP B 2 75  ? 184.782 182.894 188.820 1.00 46.25  ? 79  TRP F CH2   1 
ATOM   6533 N N     . ASP B 2 76  ? 185.043 180.883 196.559 1.00 50.32  ? 80  ASP F N     1 
ATOM   6534 C CA    . ASP B 2 76  ? 184.107 180.601 197.639 1.00 50.32  ? 80  ASP F CA    1 
ATOM   6535 C C     . ASP B 2 76  ? 183.436 181.877 198.125 1.00 50.32  ? 80  ASP F C     1 
ATOM   6536 O O     . ASP B 2 76  ? 182.212 181.921 198.311 1.00 50.32  ? 80  ASP F O     1 
ATOM   6537 C CB    . ASP B 2 76  ? 184.837 179.898 198.774 1.00 50.32  ? 80  ASP F CB    1 
ATOM   6538 C CG    . ASP B 2 76  ? 185.723 178.777 198.277 1.00 50.32  ? 80  ASP F CG    1 
ATOM   6539 O OD1   . ASP B 2 76  ? 185.183 177.733 197.855 1.00 50.32  ? 80  ASP F OD1   1 
ATOM   6540 O OD2   . ASP B 2 76  ? 186.960 178.941 198.298 1.00 50.32  ? 80  ASP F OD2   1 
ATOM   6541 N N     . ASP B 2 77  ? 184.222 182.931 198.327 1.00 48.14  ? 81  ASP F N     1 
ATOM   6542 C CA    . ASP B 2 77  ? 183.643 184.222 198.663 1.00 48.14  ? 81  ASP F CA    1 
ATOM   6543 C C     . ASP B 2 77  ? 182.690 184.697 197.582 1.00 48.14  ? 81  ASP F C     1 
ATOM   6544 O O     . ASP B 2 77  ? 181.634 185.258 197.886 1.00 48.14  ? 81  ASP F O     1 
ATOM   6545 C CB    . ASP B 2 77  ? 184.740 185.250 198.882 1.00 48.14  ? 81  ASP F CB    1 
ATOM   6546 C CG    . ASP B 2 77  ? 185.273 185.235 200.287 1.00 48.14  ? 81  ASP F CG    1 
ATOM   6547 O OD1   . ASP B 2 77  ? 185.099 184.212 200.978 1.00 48.14  ? 81  ASP F OD1   1 
ATOM   6548 O OD2   . ASP B 2 77  ? 185.865 186.253 200.706 1.00 48.14  ? 81  ASP F OD2   1 
ATOM   6549 N N     . MET B 2 78  ? 183.033 184.488 196.314 1.00 47.34  ? 82  MET F N     1 
ATOM   6550 C CA    . MET B 2 78  ? 182.137 184.966 195.270 1.00 47.34  ? 82  MET F CA    1 
ATOM   6551 C C     . MET B 2 78  ? 180.836 184.177 195.253 1.00 47.34  ? 82  MET F C     1 
ATOM   6552 O O     . MET B 2 78  ? 179.769 184.741 194.999 1.00 47.34  ? 82  MET F O     1 
ATOM   6553 C CB    . MET B 2 78  ? 182.822 184.914 193.915 1.00 47.34  ? 82  MET F CB    1 
ATOM   6554 C CG    . MET B 2 78  ? 181.978 185.461 192.801 1.00 47.34  ? 82  MET F CG    1 
ATOM   6555 S SD    . MET B 2 78  ? 181.187 187.026 193.192 1.00 47.34  ? 82  MET F SD    1 
ATOM   6556 C CE    . MET B 2 78  ? 182.594 188.098 193.302 1.00 47.34  ? 82  MET F CE    1 
ATOM   6557 N N     . GLU B 2 79  ? 180.891 182.876 195.532 1.00 49.16  ? 83  GLU F N     1 
ATOM   6558 C CA    . GLU B 2 79  ? 179.652 182.115 195.638 1.00 49.16  ? 83  GLU F CA    1 
ATOM   6559 C C     . GLU B 2 79  ? 178.809 182.601 196.801 1.00 49.16  ? 83  GLU F C     1 
ATOM   6560 O O     . GLU B 2 79  ? 177.580 182.633 196.710 1.00 49.16  ? 83  GLU F O     1 
ATOM   6561 C CB    . GLU B 2 79  ? 179.940 180.630 195.782 1.00 49.16  ? 83  GLU F CB    1 
ATOM   6562 C CG    . GLU B 2 79  ? 180.492 180.011 194.535 1.00 49.16  ? 83  GLU F CG    1 
ATOM   6563 C CD    . GLU B 2 79  ? 180.900 178.571 194.735 1.00 49.16  ? 83  GLU F CD    1 
ATOM   6564 O OE1   . GLU B 2 79  ? 180.134 177.822 195.374 1.00 49.16  ? 83  GLU F OE1   1 
ATOM   6565 O OE2   . GLU B 2 79  ? 181.988 178.189 194.257 1.00 49.16  ? 83  GLU F OE2   1 
ATOM   6566 N N     . LYS B 2 80  ? 179.447 182.992 197.904 1.00 46.70  ? 84  LYS F N     1 
ATOM   6567 C CA    . LYS B 2 80  ? 178.678 183.576 198.999 1.00 46.70  ? 84  LYS F CA    1 
ATOM   6568 C C     . LYS B 2 80  ? 178.032 184.888 198.584 1.00 46.70  ? 84  LYS F C     1 
ATOM   6569 O O     . LYS B 2 80  ? 176.881 185.157 198.937 1.00 46.70  ? 84  LYS F O     1 
ATOM   6570 C CB    . LYS B 2 80  ? 179.563 183.796 200.214 1.00 46.70  ? 84  LYS F CB    1 
ATOM   6571 C CG    . LYS B 2 80  ? 179.997 182.539 200.879 1.00 46.70  ? 84  LYS F CG    1 
ATOM   6572 C CD    . LYS B 2 80  ? 180.831 182.853 202.080 1.00 46.70  ? 84  LYS F CD    1 
ATOM   6573 C CE    . LYS B 2 80  ? 181.352 181.593 202.698 1.00 46.70  ? 84  LYS F CE    1 
ATOM   6574 N NZ    . LYS B 2 80  ? 182.189 181.909 203.872 1.00 46.70  ? 84  LYS F NZ    1 
ATOM   6575 N N     . ILE B 2 81  ? 178.764 185.721 197.850 1.00 45.46  ? 85  ILE F N     1 
ATOM   6576 C CA    . ILE B 2 81  ? 178.208 186.983 197.375 1.00 45.46  ? 85  ILE F CA    1 
ATOM   6577 C C     . ILE B 2 81  ? 176.981 186.724 196.518 1.00 45.46  ? 85  ILE F C     1 
ATOM   6578 O O     . ILE B 2 81  ? 175.936 187.359 196.688 1.00 45.46  ? 85  ILE F O     1 
ATOM   6579 C CB    . ILE B 2 81  ? 179.262 187.774 196.587 1.00 45.46  ? 85  ILE F CB    1 
ATOM   6580 C CG1   . ILE B 2 81  ? 180.418 188.203 197.474 1.00 45.46  ? 85  ILE F CG1   1 
ATOM   6581 C CG2   . ILE B 2 81  ? 178.623 188.977 195.961 1.00 45.46  ? 85  ILE F CG2   1 
ATOM   6582 C CD1   . ILE B 2 81  ? 180.109 189.340 198.329 1.00 45.46  ? 85  ILE F CD1   1 
ATOM   6583 N N     . TRP B 2 82  ? 177.091 185.790 195.579 1.00 47.11  ? 86  TRP F N     1 
ATOM   6584 C CA    . TRP B 2 82  ? 175.978 185.530 194.676 1.00 47.11  ? 86  TRP F CA    1 
ATOM   6585 C C     . TRP B 2 82  ? 174.796 184.933 195.414 1.00 47.11  ? 86  TRP F C     1 
ATOM   6586 O O     . TRP B 2 82  ? 173.646 185.269 195.124 1.00 47.11  ? 86  TRP F O     1 
ATOM   6587 C CB    . TRP B 2 82  ? 176.414 184.605 193.550 1.00 47.11  ? 86  TRP F CB    1 
ATOM   6588 C CG    . TRP B 2 82  ? 177.062 185.321 192.432 1.00 47.11  ? 86  TRP F CG    1 
ATOM   6589 C CD1   . TRP B 2 82  ? 176.790 186.580 192.003 1.00 47.11  ? 86  TRP F CD1   1 
ATOM   6590 C CD2   . TRP B 2 82  ? 178.104 184.828 191.597 1.00 47.11  ? 86  TRP F CD2   1 
ATOM   6591 N NE1   . TRP B 2 82  ? 177.597 186.901 190.949 1.00 47.11  ? 86  TRP F NE1   1 
ATOM   6592 C CE2   . TRP B 2 82  ? 178.415 185.838 190.682 1.00 47.11  ? 86  TRP F CE2   1 
ATOM   6593 C CE3   . TRP B 2 82  ? 178.802 183.625 191.534 1.00 47.11  ? 86  TRP F CE3   1 
ATOM   6594 C CZ2   . TRP B 2 82  ? 179.389 185.685 189.719 1.00 47.11  ? 86  TRP F CZ2   1 
ATOM   6595 C CZ3   . TRP B 2 82  ? 179.768 183.476 190.581 1.00 47.11  ? 86  TRP F CZ3   1 
ATOM   6596 C CH2   . TRP B 2 82  ? 180.056 184.497 189.684 1.00 47.11  ? 86  TRP F CH2   1 
ATOM   6597 N N     . HIS B 2 83  ? 175.053 184.032 196.356 1.00 48.81  ? 87  HIS F N     1 
ATOM   6598 C CA    . HIS B 2 83  ? 173.974 183.451 197.138 1.00 48.81  ? 87  HIS F CA    1 
ATOM   6599 C C     . HIS B 2 83  ? 173.241 184.524 197.924 1.00 48.81  ? 87  HIS F C     1 
ATOM   6600 O O     . HIS B 2 83  ? 172.007 184.555 197.957 1.00 48.81  ? 87  HIS F O     1 
ATOM   6601 C CB    . HIS B 2 83  ? 174.541 182.387 198.068 1.00 48.81  ? 87  HIS F CB    1 
ATOM   6602 C CG    . HIS B 2 83  ? 173.510 181.680 198.878 1.00 48.81  ? 87  HIS F CG    1 
ATOM   6603 N ND1   . HIS B 2 83  ? 172.984 180.464 198.508 1.00 48.81  ? 87  HIS F ND1   1 
ATOM   6604 C CD2   . HIS B 2 83  ? 172.910 182.012 200.043 1.00 48.81  ? 87  HIS F CD2   1 
ATOM   6605 C CE1   . HIS B 2 83  ? 172.101 180.078 199.409 1.00 48.81  ? 87  HIS F CE1   1 
ATOM   6606 N NE2   . HIS B 2 83  ? 172.036 181.001 200.350 1.00 48.81  ? 87  HIS F NE2   1 
ATOM   6607 N N     . HIS B 2 84  ? 173.990 185.414 198.570 1.00 47.17  ? 88  HIS F N     1 
ATOM   6608 C CA    . HIS B 2 84  ? 173.365 186.520 199.279 1.00 47.17  ? 88  HIS F CA    1 
ATOM   6609 C C     . HIS B 2 84  ? 172.531 187.366 198.336 1.00 47.17  ? 88  HIS F C     1 
ATOM   6610 O O     . HIS B 2 84  ? 171.402 187.736 198.662 1.00 47.17  ? 88  HIS F O     1 
ATOM   6611 C CB    . HIS B 2 84  ? 174.430 187.369 199.960 1.00 47.17  ? 88  HIS F CB    1 
ATOM   6612 C CG    . HIS B 2 84  ? 173.883 188.540 200.708 1.00 47.17  ? 88  HIS F CG    1 
ATOM   6613 N ND1   . HIS B 2 84  ? 173.471 188.457 202.018 1.00 47.17  ? 88  HIS F ND1   1 
ATOM   6614 C CD2   . HIS B 2 84  ? 173.691 189.824 200.335 1.00 47.17  ? 88  HIS F CD2   1 
ATOM   6615 C CE1   . HIS B 2 84  ? 173.041 189.638 202.417 1.00 47.17  ? 88  HIS F CE1   1 
ATOM   6616 N NE2   . HIS B 2 84  ? 173.166 190.486 201.415 1.00 47.17  ? 88  HIS F NE2   1 
ATOM   6617 N N     . THR B 2 85  ? 173.057 187.652 197.148 1.00 47.46  ? 89  THR F N     1 
ATOM   6618 C CA    . THR B 2 85  ? 172.335 188.490 196.199 1.00 47.46  ? 89  THR F CA    1 
ATOM   6619 C C     . THR B 2 85  ? 171.024 187.848 195.782 1.00 47.46  ? 89  THR F C     1 
ATOM   6620 O O     . THR B 2 85  ? 169.980 188.502 195.757 1.00 47.46  ? 89  THR F O     1 
ATOM   6621 C CB    . THR B 2 85  ? 173.203 188.751 194.981 1.00 47.46  ? 89  THR F CB    1 
ATOM   6622 O OG1   . THR B 2 85  ? 174.425 189.349 195.404 1.00 47.46  ? 89  THR F OG1   1 
ATOM   6623 C CG2   . THR B 2 85  ? 172.511 189.682 194.041 1.00 47.46  ? 89  THR F CG2   1 
ATOM   6624 N N     . PHE B 2 86  ? 171.059 186.564 195.449 1.00 49.47  ? 90  PHE F N     1 
ATOM   6625 C CA    . PHE B 2 86  ? 169.853 185.912 194.960 1.00 49.47  ? 90  PHE F CA    1 
ATOM   6626 C C     . PHE B 2 86  ? 168.817 185.754 196.059 1.00 49.47  ? 90  PHE F C     1 
ATOM   6627 O O     . PHE B 2 86  ? 167.638 186.041 195.845 1.00 49.47  ? 90  PHE F O     1 
ATOM   6628 C CB    . PHE B 2 86  ? 170.186 184.551 194.368 1.00 49.47  ? 90  PHE F CB    1 
ATOM   6629 C CG    . PHE B 2 86  ? 170.847 184.623 193.042 1.00 49.47  ? 90  PHE F CG    1 
ATOM   6630 C CD1   . PHE B 2 86  ? 170.684 185.726 192.241 1.00 49.47  ? 90  PHE F CD1   1 
ATOM   6631 C CD2   . PHE B 2 86  ? 171.635 183.592 192.596 1.00 49.47  ? 90  PHE F CD2   1 
ATOM   6632 C CE1   . PHE B 2 86  ? 171.294 185.796 191.025 1.00 49.47  ? 90  PHE F CE1   1 
ATOM   6633 C CE2   . PHE B 2 86  ? 172.244 183.660 191.382 1.00 49.47  ? 90  PHE F CE2   1 
ATOM   6634 C CZ    . PHE B 2 86  ? 172.076 184.763 190.596 1.00 49.47  ? 90  PHE F CZ    1 
ATOM   6635 N N     . TYR B 2 87  ? 169.225 185.306 197.241 1.00 51.53  ? 91  TYR F N     1 
ATOM   6636 C CA    . TYR B 2 87  ? 168.237 184.899 198.227 1.00 51.53  ? 91  TYR F CA    1 
ATOM   6637 C C     . TYR B 2 87  ? 167.919 185.963 199.260 1.00 51.53  ? 91  TYR F C     1 
ATOM   6638 O O     . TYR B 2 87  ? 166.758 186.095 199.649 1.00 51.53  ? 91  TYR F O     1 
ATOM   6639 C CB    . TYR B 2 87  ? 168.697 183.629 198.936 1.00 51.53  ? 91  TYR F CB    1 
ATOM   6640 C CG    . TYR B 2 87  ? 168.811 182.450 198.009 1.00 51.53  ? 91  TYR F CG    1 
ATOM   6641 C CD1   . TYR B 2 87  ? 167.688 181.789 197.567 1.00 51.53  ? 91  TYR F CD1   1 
ATOM   6642 C CD2   . TYR B 2 87  ? 170.042 182.007 197.572 1.00 51.53  ? 91  TYR F CD2   1 
ATOM   6643 C CE1   . TYR B 2 87  ? 167.788 180.720 196.719 1.00 51.53  ? 91  TYR F CE1   1 
ATOM   6644 C CE2   . TYR B 2 87  ? 170.150 180.941 196.726 1.00 51.53  ? 91  TYR F CE2   1 
ATOM   6645 C CZ    . TYR B 2 87  ? 169.021 180.300 196.303 1.00 51.53  ? 91  TYR F CZ    1 
ATOM   6646 O OH    . TYR B 2 87  ? 169.123 179.226 195.456 1.00 51.53  ? 91  TYR F OH    1 
ATOM   6647 N N     . ASN B 2 88  ? 168.897 186.728 199.726 1.00 50.48  ? 92  ASN F N     1 
ATOM   6648 C CA    . ASN B 2 88  ? 168.664 187.632 200.838 1.00 50.48  ? 92  ASN F CA    1 
ATOM   6649 C C     . ASN B 2 88  ? 168.490 189.083 200.424 1.00 50.48  ? 92  ASN F C     1 
ATOM   6650 O O     . ASN B 2 88  ? 168.225 189.920 201.285 1.00 50.48  ? 92  ASN F O     1 
ATOM   6651 C CB    . ASN B 2 88  ? 169.804 187.528 201.845 1.00 50.48  ? 92  ASN F CB    1 
ATOM   6652 C CG    . ASN B 2 88  ? 170.125 186.103 202.206 1.00 50.48  ? 92  ASN F CG    1 
ATOM   6653 O OD1   . ASN B 2 88  ? 171.284 185.738 202.373 1.00 50.48  ? 92  ASN F OD1   1 
ATOM   6654 N ND2   . ASN B 2 88  ? 169.096 185.281 202.322 1.00 50.48  ? 92  ASN F ND2   1 
ATOM   6655 N N     . GLU B 2 89  ? 168.634 189.409 199.145 1.00 50.80  ? 93  GLU F N     1 
ATOM   6656 C CA    . GLU B 2 89  ? 168.435 190.775 198.676 1.00 50.80  ? 93  GLU F CA    1 
ATOM   6657 C C     . GLU B 2 89  ? 167.333 190.877 197.637 1.00 50.80  ? 93  GLU F C     1 
ATOM   6658 O O     . GLU B 2 89  ? 166.521 191.803 197.692 1.00 50.80  ? 93  GLU F O     1 
ATOM   6659 C CB    . GLU B 2 89  ? 169.740 191.334 198.105 1.00 50.80  ? 93  GLU F CB    1 
ATOM   6660 C CG    . GLU B 2 89  ? 170.810 191.589 199.139 1.00 50.80  ? 93  GLU F CG    1 
ATOM   6661 C CD    . GLU B 2 89  ? 170.690 192.948 199.797 1.00 50.80  ? 93  GLU F CD    1 
ATOM   6662 O OE1   . GLU B 2 89  ? 170.106 193.864 199.188 1.00 50.80  ? 93  GLU F OE1   1 
ATOM   6663 O OE2   . GLU B 2 89  ? 171.185 193.105 200.929 1.00 50.80  ? 93  GLU F OE2   1 
ATOM   6664 N N     . LEU B 2 90  ? 167.289 189.959 196.681 1.00 53.28  ? 94  LEU F N     1 
ATOM   6665 C CA    . LEU B 2 90  ? 166.221 189.931 195.694 1.00 53.28  ? 94  LEU F CA    1 
ATOM   6666 C C     . LEU B 2 90  ? 165.109 188.960 196.049 1.00 53.28  ? 94  LEU F C     1 
ATOM   6667 O O     . LEU B 2 90  ? 163.970 189.163 195.624 1.00 53.28  ? 94  LEU F O     1 
ATOM   6668 C CB    . LEU B 2 90  ? 166.776 189.557 194.320 1.00 53.28  ? 94  LEU F CB    1 
ATOM   6669 C CG    . LEU B 2 90  ? 167.782 190.508 193.697 1.00 53.28  ? 94  LEU F CG    1 
ATOM   6670 C CD1   . LEU B 2 90  ? 168.316 189.897 192.432 1.00 53.28  ? 94  LEU F CD1   1 
ATOM   6671 C CD2   . LEU B 2 90  ? 167.129 191.830 193.415 1.00 53.28  ? 94  LEU F CD2   1 
ATOM   6672 N N     . ARG B 2 91  ? 165.418 187.910 196.803 1.00 56.90  ? 95  ARG F N     1 
ATOM   6673 C CA    . ARG B 2 91  ? 164.429 186.932 197.235 1.00 56.90  ? 95  ARG F CA    1 
ATOM   6674 C C     . ARG B 2 91  ? 163.791 186.232 196.043 1.00 56.90  ? 95  ARG F C     1 
ATOM   6675 O O     . ARG B 2 91  ? 162.572 186.153 195.917 1.00 56.90  ? 95  ARG F O     1 
ATOM   6676 C CB    . ARG B 2 91  ? 163.371 187.579 198.123 1.00 56.90  ? 95  ARG F CB    1 
ATOM   6677 C CG    . ARG B 2 91  ? 163.801 187.724 199.561 1.00 56.90  ? 95  ARG F CG    1 
ATOM   6678 C CD    . ARG B 2 91  ? 162.882 188.659 200.304 1.00 56.90  ? 95  ARG F CD    1 
ATOM   6679 N NE    . ARG B 2 91  ? 163.018 190.023 199.817 1.00 56.90  ? 95  ARG F NE    1 
ATOM   6680 C CZ    . ARG B 2 91  ? 163.944 190.870 200.246 1.00 56.90  ? 95  ARG F CZ    1 
ATOM   6681 N NH1   . ARG B 2 91  ? 164.810 190.487 201.171 1.00 56.90  ? 95  ARG F NH1   1 
ATOM   6682 N NH2   . ARG B 2 91  ? 164.002 192.099 199.754 1.00 56.90  ? 95  ARG F NH2   1 
ATOM   6683 N N     . VAL B 2 92  ? 164.633 185.710 195.162 1.00 54.64  ? 96  VAL F N     1 
ATOM   6684 C CA    . VAL B 2 92  ? 164.178 185.000 193.980 1.00 54.64  ? 96  VAL F CA    1 
ATOM   6685 C C     . VAL B 2 92  ? 164.866 183.649 193.950 1.00 54.64  ? 96  VAL F C     1 
ATOM   6686 O O     . VAL B 2 92  ? 165.882 183.428 194.607 1.00 54.64  ? 96  VAL F O     1 
ATOM   6687 C CB    . VAL B 2 92  ? 164.468 185.780 192.687 1.00 54.64  ? 96  VAL F CB    1 
ATOM   6688 C CG1   . VAL B 2 92  ? 163.828 187.131 192.758 1.00 54.64  ? 96  VAL F CG1   1 
ATOM   6689 C CG2   . VAL B 2 92  ? 165.948 185.921 192.485 1.00 54.64  ? 96  VAL F CG2   1 
ATOM   6690 N N     . ALA B 2 93  ? 164.296 182.738 193.181 1.00 56.57  ? 97  ALA F N     1 
ATOM   6691 C CA    . ALA B 2 93  ? 164.878 181.422 193.036 1.00 56.57  ? 97  ALA F CA    1 
ATOM   6692 C C     . ALA B 2 93  ? 165.538 181.324 191.677 1.00 56.57  ? 97  ALA F C     1 
ATOM   6693 O O     . ALA B 2 93  ? 164.834 181.364 190.658 1.00 56.57  ? 97  ALA F O     1 
ATOM   6694 C CB    . ALA B 2 93  ? 163.816 180.345 193.188 1.00 56.57  ? 97  ALA F CB    1 
ATOM   6695 N N     . PRO B 2 94  ? 166.862 181.185 191.600 1.00 55.12  ? 98  PRO F N     1 
ATOM   6696 C CA    . PRO B 2 94  ? 167.535 181.234 190.299 1.00 55.12  ? 98  PRO F CA    1 
ATOM   6697 C C     . PRO B 2 94  ? 167.294 180.023 189.423 1.00 55.12  ? 98  PRO F C     1 
ATOM   6698 O O     . PRO B 2 94  ? 167.843 179.967 188.324 1.00 55.12  ? 98  PRO F O     1 
ATOM   6699 C CB    . PRO B 2 94  ? 169.010 181.339 190.685 1.00 55.12  ? 98  PRO F CB    1 
ATOM   6700 C CG    . PRO B 2 94  ? 169.087 180.699 192.005 1.00 55.12  ? 98  PRO F CG    1 
ATOM   6701 C CD    . PRO B 2 94  ? 167.811 180.993 192.705 1.00 55.12  ? 98  PRO F CD    1 
ATOM   6702 N N     . GLU B 2 95  ? 166.499 179.050 189.853 1.00 57.62  ? 99  GLU F N     1 
ATOM   6703 C CA    . GLU B 2 95  ? 166.185 177.926 188.986 1.00 57.62  ? 99  GLU F CA    1 
ATOM   6704 C C     . GLU B 2 95  ? 165.190 178.298 187.906 1.00 57.62  ? 99  GLU F C     1 
ATOM   6705 O O     . GLU B 2 95  ? 164.935 177.489 187.012 1.00 57.62  ? 99  GLU F O     1 
ATOM   6706 C CB    . GLU B 2 95  ? 165.621 176.768 189.797 1.00 57.62  ? 99  GLU F CB    1 
ATOM   6707 C CG    . GLU B 2 95  ? 166.365 176.503 191.070 1.00 57.62  ? 99  GLU F CG    1 
ATOM   6708 C CD    . GLU B 2 95  ? 165.764 177.237 192.238 1.00 57.62  ? 99  GLU F CD    1 
ATOM   6709 O OE1   . GLU B 2 95  ? 164.564 177.562 192.169 1.00 57.62  ? 99  GLU F OE1   1 
ATOM   6710 O OE2   . GLU B 2 95  ? 166.488 177.485 193.223 1.00 57.62  ? 99  GLU F OE2   1 
ATOM   6711 N N     . GLU B 2 96  ? 164.617 179.495 187.975 1.00 59.34  ? 100 GLU F N     1 
ATOM   6712 C CA    . GLU B 2 96  ? 163.547 179.891 187.073 1.00 59.34  ? 100 GLU F CA    1 
ATOM   6713 C C     . GLU B 2 96  ? 163.779 181.276 186.488 1.00 59.34  ? 100 GLU F C     1 
ATOM   6714 O O     . GLU B 2 96  ? 162.829 181.919 186.039 1.00 59.34  ? 100 GLU F O     1 
ATOM   6715 C CB    . GLU B 2 96  ? 162.206 179.835 187.803 1.00 59.34  ? 100 GLU F CB    1 
ATOM   6716 C CG    . GLU B 2 96  ? 162.138 180.785 188.972 1.00 59.34  ? 100 GLU F CG    1 
ATOM   6717 C CD    . GLU B 2 96  ? 160.878 180.625 189.794 1.00 59.34  ? 100 GLU F CD    1 
ATOM   6718 O OE1   . GLU B 2 96  ? 160.057 179.748 189.465 1.00 59.34  ? 100 GLU F OE1   1 
ATOM   6719 O OE2   . GLU B 2 96  ? 160.708 181.376 190.777 1.00 59.34  ? 100 GLU F OE2   1 
ATOM   6720 N N     . HIS B 2 97  ? 165.022 181.746 186.474 1.00 55.37  ? 101 HIS F N     1 
ATOM   6721 C CA    . HIS B 2 97  ? 165.339 183.074 185.970 1.00 55.37  ? 101 HIS F CA    1 
ATOM   6722 C C     . HIS B 2 97  ? 166.622 183.032 185.155 1.00 55.37  ? 101 HIS F C     1 
ATOM   6723 O O     . HIS B 2 97  ? 167.658 182.569 185.664 1.00 55.37  ? 101 HIS F O     1 
ATOM   6724 C CB    . HIS B 2 97  ? 165.482 184.059 187.123 1.00 55.37  ? 101 HIS F CB    1 
ATOM   6725 C CG    . HIS B 2 97  ? 164.181 184.543 187.672 1.00 55.37  ? 101 HIS F CG    1 
ATOM   6726 N ND1   . HIS B 2 97  ? 163.535 183.917 188.713 1.00 55.37  ? 101 HIS F ND1   1 
ATOM   6727 C CD2   . HIS B 2 97  ? 163.402 185.591 187.323 1.00 55.37  ? 101 HIS F CD2   1 
ATOM   6728 C CE1   . HIS B 2 97  ? 162.417 184.562 188.985 1.00 55.37  ? 101 HIS F CE1   1 
ATOM   6729 N NE2   . HIS B 2 97  ? 162.313 185.582 188.156 1.00 55.37  ? 101 HIS F NE2   1 
ATOM   6730 N N     . PRO B 2 98  ? 166.610 183.482 183.907 1.00 50.71  ? 102 PRO F N     1 
ATOM   6731 C CA    . PRO B 2 98  ? 167.870 183.717 183.204 1.00 50.71  ? 102 PRO F CA    1 
ATOM   6732 C C     . PRO B 2 98  ? 168.639 184.839 183.871 1.00 50.71  ? 102 PRO F C     1 
ATOM   6733 O O     . PRO B 2 98  ? 168.058 185.741 184.471 1.00 50.71  ? 102 PRO F O     1 
ATOM   6734 C CB    . PRO B 2 98  ? 167.421 184.108 181.797 1.00 50.71  ? 102 PRO F CB    1 
ATOM   6735 C CG    . PRO B 2 98  ? 166.056 183.571 181.685 1.00 50.71  ? 102 PRO F CG    1 
ATOM   6736 C CD    . PRO B 2 98  ? 165.454 183.677 183.029 1.00 50.71  ? 102 PRO F CD    1 
ATOM   6737 N N     . THR B 2 99  ? 169.961 184.784 183.760 1.00 47.73  ? 103 THR F N     1 
ATOM   6738 C CA    . THR B 2 99  ? 170.834 185.716 184.460 1.00 47.73  ? 103 THR F CA    1 
ATOM   6739 C C     . THR B 2 99  ? 171.846 186.288 183.486 1.00 47.73  ? 103 THR F C     1 
ATOM   6740 O O     . THR B 2 99  ? 172.599 185.538 182.867 1.00 47.73  ? 103 THR F O     1 
ATOM   6741 C CB    . THR B 2 99  ? 171.546 185.017 185.612 1.00 47.73  ? 103 THR F CB    1 
ATOM   6742 O OG1   . THR B 2 99  ? 170.587 184.274 186.366 1.00 47.73  ? 103 THR F OG1   1 
ATOM   6743 C CG2   . THR B 2 99  ? 172.208 186.016 186.516 1.00 47.73  ? 103 THR F CG2   1 
ATOM   6744 N N     . LEU B 2 100 ? 171.874 187.605 183.361 1.00 44.18  ? 104 LEU F N     1 
ATOM   6745 C CA    . LEU B 2 100 ? 172.875 188.289 182.558 1.00 44.18  ? 104 LEU F CA    1 
ATOM   6746 C C     . LEU B 2 100 ? 173.960 188.827 183.474 1.00 44.18  ? 104 LEU F C     1 
ATOM   6747 O O     . LEU B 2 100 ? 173.672 189.582 184.402 1.00 44.18  ? 104 LEU F O     1 
ATOM   6748 C CB    . LEU B 2 100 ? 172.248 189.425 181.755 1.00 44.18  ? 104 LEU F CB    1 
ATOM   6749 C CG    . LEU B 2 100 ? 173.189 190.324 180.964 1.00 44.18  ? 104 LEU F CG    1 
ATOM   6750 C CD1   . LEU B 2 100 ? 172.641 190.574 179.603 1.00 44.18  ? 104 LEU F CD1   1 
ATOM   6751 C CD2   . LEU B 2 100 ? 173.351 191.630 181.666 1.00 44.18  ? 104 LEU F CD2   1 
ATOM   6752 N N     . LEU B 2 101 ? 175.200 188.436 183.217 1.00 43.64  ? 105 LEU F N     1 
ATOM   6753 C CA    . LEU B 2 101 ? 176.338 188.853 184.015 1.00 43.64  ? 105 LEU F CA    1 
ATOM   6754 C C     . LEU B 2 101 ? 177.248 189.726 183.174 1.00 43.64  ? 105 LEU F C     1 
ATOM   6755 O O     . LEU B 2 101 ? 177.224 189.665 181.947 1.00 43.64  ? 105 LEU F O     1 
ATOM   6756 C CB    . LEU B 2 101 ? 177.101 187.656 184.535 1.00 43.64  ? 105 LEU F CB    1 
ATOM   6757 C CG    . LEU B 2 101 ? 176.226 186.681 185.298 1.00 43.64  ? 105 LEU F CG    1 
ATOM   6758 C CD1   . LEU B 2 101 ? 177.003 185.454 185.612 1.00 43.64  ? 105 LEU F CD1   1 
ATOM   6759 C CD2   . LEU B 2 101 ? 175.771 187.325 186.561 1.00 43.64  ? 105 LEU F CD2   1 
ATOM   6760 N N     . THR B 2 102 ? 178.053 190.540 183.831 1.00 42.11  ? 106 THR F N     1 
ATOM   6761 C CA    . THR B 2 102 ? 178.821 191.568 183.153 1.00 42.11  ? 106 THR F CA    1 
ATOM   6762 C C     . THR B 2 102 ? 180.296 191.422 183.487 1.00 42.11  ? 106 THR F C     1 
ATOM   6763 O O     . THR B 2 102 ? 180.651 191.088 184.616 1.00 42.11  ? 106 THR F O     1 
ATOM   6764 C CB    . THR B 2 102 ? 178.312 192.949 183.551 1.00 42.11  ? 106 THR F CB    1 
ATOM   6765 O OG1   . THR B 2 102 ? 176.886 192.980 183.433 1.00 42.11  ? 106 THR F OG1   1 
ATOM   6766 C CG2   . THR B 2 102 ? 178.865 193.984 182.646 1.00 42.11  ? 106 THR F CG2   1 
ATOM   6767 N N     . GLU B 2 103 ? 181.155 191.676 182.503 1.00 41.62  ? 107 GLU F N     1 
ATOM   6768 C CA    . GLU B 2 103 ? 182.587 191.486 182.669 1.00 41.62  ? 107 GLU F CA    1 
ATOM   6769 C C     . GLU B 2 103 ? 183.333 192.560 181.899 1.00 41.62  ? 107 GLU F C     1 
ATOM   6770 O O     . GLU B 2 103 ? 182.813 193.122 180.939 1.00 41.62  ? 107 GLU F O     1 
ATOM   6771 C CB    . GLU B 2 103 ? 183.020 190.104 182.187 1.00 41.62  ? 107 GLU F CB    1 
ATOM   6772 C CG    . GLU B 2 103 ? 184.337 189.645 182.760 1.00 41.62  ? 107 GLU F CG    1 
ATOM   6773 C CD    . GLU B 2 103 ? 185.074 188.708 181.834 1.00 41.62  ? 107 GLU F CD    1 
ATOM   6774 O OE1   . GLU B 2 103 ? 184.780 188.725 180.623 1.00 41.62  ? 107 GLU F OE1   1 
ATOM   6775 O OE2   . GLU B 2 103 ? 185.956 187.963 182.313 1.00 41.62  ? 107 GLU F OE2   1 
ATOM   6776 N N     . ALA B 2 104 ? 184.552 192.839 182.329 1.00 39.15  ? 108 ALA F N     1 
ATOM   6777 C CA    . ALA B 2 104 ? 185.383 193.837 181.683 1.00 39.15  ? 108 ALA F CA    1 
ATOM   6778 C C     . ALA B 2 104 ? 186.141 193.232 180.508 1.00 39.15  ? 108 ALA F C     1 
ATOM   6779 O O     . ALA B 2 104 ? 186.336 192.021 180.442 1.00 39.15  ? 108 ALA F O     1 
ATOM   6780 C CB    . ALA B 2 104 ? 186.366 194.424 182.684 1.00 39.15  ? 108 ALA F CB    1 
ATOM   6781 N N     . PRO B 2 105 ? 186.569 194.053 179.555 1.00 37.67  ? 109 PRO F N     1 
ATOM   6782 C CA    . PRO B 2 105 ? 187.347 193.524 178.437 1.00 37.67  ? 109 PRO F CA    1 
ATOM   6783 C C     . PRO B 2 105 ? 188.702 193.028 178.888 1.00 37.67  ? 109 PRO F C     1 
ATOM   6784 O O     . PRO B 2 105 ? 189.260 193.498 179.878 1.00 37.67  ? 109 PRO F O     1 
ATOM   6785 C CB    . PRO B 2 105 ? 187.495 194.729 177.509 1.00 37.67  ? 109 PRO F CB    1 
ATOM   6786 C CG    . PRO B 2 105 ? 186.410 195.618 177.875 1.00 37.67  ? 109 PRO F CG    1 
ATOM   6787 C CD    . PRO B 2 105 ? 186.199 195.455 179.333 1.00 37.67  ? 109 PRO F CD    1 
ATOM   6788 N N     . LEU B 2 106 ? 189.228 192.062 178.141 1.00 38.01  ? 110 LEU F N     1 
ATOM   6789 C CA    . LEU B 2 106 ? 190.604 191.601 178.291 1.00 38.01  ? 110 LEU F CA    1 
ATOM   6790 C C     . LEU B 2 106 ? 190.859 190.983 179.661 1.00 38.01  ? 110 LEU F C     1 
ATOM   6791 O O     . LEU B 2 106 ? 191.889 191.225 180.287 1.00 38.01  ? 110 LEU F O     1 
ATOM   6792 C CB    . LEU B 2 106 ? 191.588 192.741 178.031 1.00 38.01  ? 110 LEU F CB    1 
ATOM   6793 C CG    . LEU B 2 106 ? 191.529 193.462 176.692 1.00 38.01  ? 110 LEU F CG    1 
ATOM   6794 C CD1   . LEU B 2 106 ? 192.578 194.532 176.649 1.00 38.01  ? 110 LEU F CD1   1 
ATOM   6795 C CD2   . LEU B 2 106 ? 191.732 192.488 175.574 1.00 38.01  ? 110 LEU F CD2   1 
ATOM   6796 N N     . ASN B 2 107 ? 189.930 190.175 180.119 1.00 40.12  ? 111 ASN F N     1 
ATOM   6797 C CA    . ASN B 2 107 ? 190.182 189.393 181.317 1.00 40.12  ? 111 ASN F CA    1 
ATOM   6798 C C     . ASN B 2 107 ? 190.596 187.985 180.946 1.00 40.12  ? 111 ASN F C     1 
ATOM   6799 O O     . ASN B 2 107 ? 190.456 187.571 179.796 1.00 40.12  ? 111 ASN F O     1 
ATOM   6800 C CB    . ASN B 2 107 ? 188.943 189.329 182.212 1.00 40.12  ? 111 ASN F CB    1 
ATOM   6801 C CG    . ASN B 2 107 ? 188.744 190.571 183.014 1.00 40.12  ? 111 ASN F CG    1 
ATOM   6802 O OD1   . ASN B 2 107 ? 189.701 191.218 183.421 1.00 40.12  ? 111 ASN F OD1   1 
ATOM   6803 N ND2   . ASN B 2 107 ? 187.501 190.885 183.304 1.00 40.12  ? 111 ASN F ND2   1 
ATOM   6804 N N     . PRO B 2 108 ? 191.128 187.221 181.893 1.00 41.61  ? 112 PRO F N     1 
ATOM   6805 C CA    . PRO B 2 108 ? 191.370 185.804 181.637 1.00 41.61  ? 112 PRO F CA    1 
ATOM   6806 C C     . PRO B 2 108 ? 190.110 185.096 181.181 1.00 41.61  ? 112 PRO F C     1 
ATOM   6807 O O     . PRO B 2 108 ? 188.991 185.557 181.390 1.00 41.61  ? 112 PRO F O     1 
ATOM   6808 C CB    . PRO B 2 108 ? 191.838 185.285 182.993 1.00 41.61  ? 112 PRO F CB    1 
ATOM   6809 C CG    . PRO B 2 108 ? 192.483 186.440 183.601 1.00 41.61  ? 112 PRO F CG    1 
ATOM   6810 C CD    . PRO B 2 108 ? 191.724 187.642 183.168 1.00 41.61  ? 112 PRO F CD    1 
ATOM   6811 N N     . LYS B 2 109 ? 190.304 183.961 180.527 1.00 46.95  ? 113 LYS F N     1 
ATOM   6812 C CA    . LYS B 2 109 ? 189.162 183.211 180.037 1.00 46.95  ? 113 LYS F CA    1 
ATOM   6813 C C     . LYS B 2 109 ? 188.598 182.286 181.099 1.00 46.95  ? 113 LYS F C     1 
ATOM   6814 O O     . LYS B 2 109 ? 187.396 181.990 181.092 1.00 46.95  ? 113 LYS F O     1 
ATOM   6815 C CB    . LYS B 2 109 ? 189.560 182.416 178.805 1.00 46.95  ? 113 LYS F CB    1 
ATOM   6816 C CG    . LYS B 2 109 ? 189.878 183.271 177.613 1.00 46.95  ? 113 LYS F CG    1 
ATOM   6817 C CD    . LYS B 2 109 ? 189.901 182.427 176.363 1.00 46.95  ? 113 LYS F CD    1 
ATOM   6818 C CE    . LYS B 2 109 ? 189.594 183.254 175.136 1.00 46.95  ? 113 LYS F CE    1 
ATOM   6819 N NZ    . LYS B 2 109 ? 189.295 182.385 173.971 1.00 46.95  ? 113 LYS F NZ    1 
ATOM   6820 N N     . ALA B 2 110 ? 189.443 181.822 182.013 1.00 47.10  ? 114 ALA F N     1 
ATOM   6821 C CA    . ALA B 2 110 ? 188.952 180.982 183.091 1.00 47.10  ? 114 ALA F CA    1 
ATOM   6822 C C     . ALA B 2 110 ? 187.976 181.738 183.971 1.00 47.10  ? 114 ALA F C     1 
ATOM   6823 O O     . ALA B 2 110 ? 187.121 181.125 184.609 1.00 47.10  ? 114 ALA F O     1 
ATOM   6824 C CB    . ALA B 2 110 ? 190.116 180.450 183.914 1.00 47.10  ? 114 ALA F CB    1 
ATOM   6825 N N     . ASN B 2 111 ? 188.063 183.064 183.994 1.00 46.64  ? 115 ASN F N     1 
ATOM   6826 C CA    . ASN B 2 111 ? 187.087 183.856 184.726 1.00 46.64  ? 115 ASN F CA    1 
ATOM   6827 C C     . ASN B 2 111 ? 185.678 183.569 184.225 1.00 46.64  ? 115 ASN F C     1 
ATOM   6828 O O     . ASN B 2 111 ? 184.809 183.138 184.988 1.00 46.64  ? 115 ASN F O     1 
ATOM   6829 C CB    . ASN B 2 111 ? 187.416 185.337 184.592 1.00 46.64  ? 115 ASN F CB    1 
ATOM   6830 C CG    . ASN B 2 111 ? 186.898 186.147 185.744 1.00 46.64  ? 115 ASN F CG    1 
ATOM   6831 O OD1   . ASN B 2 111 ? 186.713 185.633 186.832 1.00 46.64  ? 115 ASN F OD1   1 
ATOM   6832 N ND2   . ASN B 2 111 ? 186.638 187.415 185.507 1.00 46.64  ? 115 ASN F ND2   1 
ATOM   6833 N N     . ARG B 2 112 ? 185.442 183.784 182.930 1.00 49.30  ? 116 ARG F N     1 
ATOM   6834 C CA    . ARG B 2 112 ? 184.124 183.523 182.363 1.00 49.30  ? 116 ARG F CA    1 
ATOM   6835 C C     . ARG B 2 112 ? 183.766 182.053 182.451 1.00 49.30  ? 116 ARG F C     1 
ATOM   6836 O O     . ARG B 2 112 ? 182.610 181.703 182.710 1.00 49.30  ? 116 ARG F O     1 
ATOM   6837 C CB    . ARG B 2 112 ? 184.071 183.972 180.908 1.00 49.30  ? 116 ARG F CB    1 
ATOM   6838 C CG    . ARG B 2 112 ? 184.259 185.436 180.701 1.00 49.30  ? 116 ARG F CG    1 
ATOM   6839 C CD    . ARG B 2 112 ? 184.705 185.717 179.294 1.00 49.30  ? 116 ARG F CD    1 
ATOM   6840 N NE    . ARG B 2 112 ? 183.606 185.721 178.341 1.00 49.30  ? 116 ARG F NE    1 
ATOM   6841 C CZ    . ARG B 2 112 ? 183.095 186.823 177.812 1.00 49.30  ? 116 ARG F CZ    1 
ATOM   6842 N NH1   . ARG B 2 112 ? 183.575 188.004 178.153 1.00 49.30  ? 116 ARG F NH1   1 
ATOM   6843 N NH2   . ARG B 2 112 ? 182.101 186.747 176.947 1.00 49.30  ? 116 ARG F NH2   1 
ATOM   6844 N N     . GLU B 2 113 ? 184.735 181.172 182.215 1.00 51.01  ? 117 GLU F N     1 
ATOM   6845 C CA    . GLU B 2 113 ? 184.418 179.751 182.210 1.00 51.01  ? 117 GLU F CA    1 
ATOM   6846 C C     . GLU B 2 113 ? 183.923 179.295 183.573 1.00 51.01  ? 117 GLU F C     1 
ATOM   6847 O O     . GLU B 2 113 ? 182.880 178.641 183.677 1.00 51.01  ? 117 GLU F O     1 
ATOM   6848 C CB    . GLU B 2 113 ? 185.633 178.950 181.771 1.00 51.01  ? 117 GLU F CB    1 
ATOM   6849 C CG    . GLU B 2 113 ? 185.937 179.099 180.305 1.00 51.01  ? 117 GLU F CG    1 
ATOM   6850 C CD    . GLU B 2 113 ? 187.265 178.489 179.926 1.00 51.01  ? 117 GLU F CD    1 
ATOM   6851 O OE1   . GLU B 2 113 ? 187.872 177.803 180.773 1.00 51.01  ? 117 GLU F OE1   1 
ATOM   6852 O OE2   . GLU B 2 113 ? 187.716 178.704 178.784 1.00 51.01  ? 117 GLU F OE2   1 
ATOM   6853 N N     . LYS B 2 114 ? 184.643 179.648 184.639 1.00 49.51  ? 118 LYS F N     1 
ATOM   6854 C CA    . LYS B 2 114 ? 184.199 179.279 185.975 1.00 49.51  ? 118 LYS F CA    1 
ATOM   6855 C C     . LYS B 2 114 ? 182.925 180.002 186.363 1.00 49.51  ? 118 LYS F C     1 
ATOM   6856 O O     . LYS B 2 114 ? 182.088 179.435 187.067 1.00 49.51  ? 118 LYS F O     1 
ATOM   6857 C CB    . LYS B 2 114 ? 185.284 179.569 186.997 1.00 49.51  ? 118 LYS F CB    1 
ATOM   6858 C CG    . LYS B 2 114 ? 186.370 178.537 187.036 1.00 49.51  ? 118 LYS F CG    1 
ATOM   6859 C CD    . LYS B 2 114 ? 187.015 178.481 188.401 1.00 49.51  ? 118 LYS F CD    1 
ATOM   6860 C CE    . LYS B 2 114 ? 185.966 178.346 189.495 1.00 49.51  ? 118 LYS F CE    1 
ATOM   6861 N NZ    . LYS B 2 114 ? 185.054 177.192 189.281 1.00 49.51  ? 118 LYS F NZ    1 
ATOM   6862 N N     . MET B 2 115 ? 182.750 181.242 185.914 1.00 50.14  ? 119 MET F N     1 
ATOM   6863 C CA    . MET B 2 115 ? 181.520 181.958 186.211 1.00 50.14  ? 119 MET F CA    1 
ATOM   6864 C C     . MET B 2 115 ? 180.312 181.202 185.686 1.00 50.14  ? 119 MET F C     1 
ATOM   6865 O O     . MET B 2 115 ? 179.339 180.979 186.414 1.00 50.14  ? 119 MET F O     1 
ATOM   6866 C CB    . MET B 2 115 ? 181.599 183.355 185.614 1.00 50.14  ? 119 MET F CB    1 
ATOM   6867 C CG    . MET B 2 115 ? 180.443 184.241 185.921 1.00 50.14  ? 119 MET F CG    1 
ATOM   6868 S SD    . MET B 2 115 ? 180.582 185.796 185.033 1.00 50.14  ? 119 MET F SD    1 
ATOM   6869 C CE    . MET B 2 115 ? 182.199 186.339 185.549 1.00 50.14  ? 119 MET F CE    1 
ATOM   6870 N N     . THR B 2 116 ? 180.363 180.768 184.428 1.00 51.41  ? 120 THR F N     1 
ATOM   6871 C CA    . THR B 2 116 ? 179.210 180.062 183.879 1.00 51.41  ? 120 THR F CA    1 
ATOM   6872 C C     . THR B 2 116 ? 179.083 178.664 184.447 1.00 51.41  ? 120 THR F C     1 
ATOM   6873 O O     . THR B 2 116 ? 177.965 178.179 184.636 1.00 51.41  ? 120 THR F O     1 
ATOM   6874 C CB    . THR B 2 116 ? 179.278 179.992 182.361 1.00 51.41  ? 120 THR F CB    1 
ATOM   6875 O OG1   . THR B 2 116 ? 180.167 178.947 181.969 1.00 51.41  ? 120 THR F OG1   1 
ATOM   6876 C CG2   . THR B 2 116 ? 179.758 181.293 181.817 1.00 51.41  ? 120 THR F CG2   1 
ATOM   6877 N N     . GLN B 2 117 ? 180.198 178.000 184.729 1.00 52.39  ? 121 GLN F N     1 
ATOM   6878 C CA    . GLN B 2 117 ? 180.110 176.704 185.382 1.00 52.39  ? 121 GLN F CA    1 
ATOM   6879 C C     . GLN B 2 117 ? 179.365 176.817 186.702 1.00 52.39  ? 121 GLN F C     1 
ATOM   6880 O O     . GLN B 2 117 ? 178.488 176.004 187.007 1.00 52.39  ? 121 GLN F O     1 
ATOM   6881 C CB    . GLN B 2 117 ? 181.504 176.137 185.597 1.00 52.39  ? 121 GLN F CB    1 
ATOM   6882 C CG    . GLN B 2 117 ? 181.530 174.903 186.437 1.00 52.39  ? 121 GLN F CG    1 
ATOM   6883 C CD    . GLN B 2 117 ? 182.923 174.374 186.604 1.00 52.39  ? 121 GLN F CD    1 
ATOM   6884 O OE1   . GLN B 2 117 ? 183.873 174.913 186.042 1.00 52.39  ? 121 GLN F OE1   1 
ATOM   6885 N NE2   . GLN B 2 117 ? 183.062 173.315 187.383 1.00 52.39  ? 121 GLN F NE2   1 
ATOM   6886 N N     . ILE B 2 118 ? 179.690 177.839 187.490 1.00 50.93  ? 122 ILE F N     1 
ATOM   6887 C CA    . ILE B 2 118 ? 179.011 178.049 188.764 1.00 50.93  ? 122 ILE F CA    1 
ATOM   6888 C C     . ILE B 2 118 ? 177.540 178.350 188.542 1.00 50.93  ? 122 ILE F C     1 
ATOM   6889 O O     . ILE B 2 118 ? 176.670 177.768 189.191 1.00 50.93  ? 122 ILE F O     1 
ATOM   6890 C CB    . ILE B 2 118 ? 179.698 179.171 189.553 1.00 50.93  ? 122 ILE F CB    1 
ATOM   6891 C CG1   . ILE B 2 118 ? 180.924 178.626 190.261 1.00 50.93  ? 122 ILE F CG1   1 
ATOM   6892 C CG2   . ILE B 2 118 ? 178.754 179.766 190.550 1.00 50.93  ? 122 ILE F CG2   1 
ATOM   6893 C CD1   . ILE B 2 118 ? 181.672 179.671 191.012 1.00 50.93  ? 122 ILE F CD1   1 
ATOM   6894 N N     . MET B 2 119 ? 177.239 179.258 187.616 1.00 51.79  ? 123 MET F N     1 
ATOM   6895 C CA    . MET B 2 119 ? 175.851 179.656 187.425 1.00 51.79  ? 123 MET F CA    1 
ATOM   6896 C C     . MET B 2 119 ? 174.994 178.493 186.958 1.00 51.79  ? 123 MET F C     1 
ATOM   6897 O O     . MET B 2 119 ? 173.795 178.450 187.238 1.00 51.79  ? 123 MET F O     1 
ATOM   6898 C CB    . MET B 2 119 ? 175.764 180.806 186.434 1.00 51.79  ? 123 MET F CB    1 
ATOM   6899 C CG    . MET B 2 119 ? 175.960 182.154 187.068 1.00 51.79  ? 123 MET F CG    1 
ATOM   6900 S SD    . MET B 2 119 ? 174.772 182.450 188.368 1.00 51.79  ? 123 MET F SD    1 
ATOM   6901 C CE    . MET B 2 119 ? 175.381 183.992 189.005 1.00 51.79  ? 123 MET F CE    1 
ATOM   6902 N N     . PHE B 2 120 ? 175.578 177.542 186.243 1.00 53.04  ? 124 PHE F N     1 
ATOM   6903 C CA    . PHE B 2 120 ? 174.762 176.434 185.770 1.00 53.04  ? 124 PHE F CA    1 
ATOM   6904 C C     . PHE B 2 120 ? 174.699 175.288 186.764 1.00 53.04  ? 124 PHE F C     1 
ATOM   6905 O O     . PHE B 2 120 ? 173.674 174.609 186.845 1.00 53.04  ? 124 PHE F O     1 
ATOM   6906 C CB    . PHE B 2 120 ? 175.283 175.931 184.432 1.00 53.04  ? 124 PHE F CB    1 
ATOM   6907 C CG    . PHE B 2 120 ? 174.782 176.713 183.272 1.00 53.04  ? 124 PHE F CG    1 
ATOM   6908 C CD1   . PHE B 2 120 ? 173.506 177.213 183.267 1.00 53.04  ? 124 PHE F CD1   1 
ATOM   6909 C CD2   . PHE B 2 120 ? 175.588 176.960 182.193 1.00 53.04  ? 124 PHE F CD2   1 
ATOM   6910 C CE1   . PHE B 2 120 ? 173.052 177.932 182.214 1.00 53.04  ? 124 PHE F CE1   1 
ATOM   6911 C CE2   . PHE B 2 120 ? 175.130 177.678 181.139 1.00 53.04  ? 124 PHE F CE2   1 
ATOM   6912 C CZ    . PHE B 2 120 ? 173.863 178.165 181.150 1.00 53.04  ? 124 PHE F CZ    1 
ATOM   6913 N N     . GLU B 2 121 ? 175.757 175.053 187.530 1.00 54.91  ? 125 GLU F N     1 
ATOM   6914 C CA    . GLU B 2 121 ? 175.787 173.898 188.413 1.00 54.91  ? 125 GLU F CA    1 
ATOM   6915 C C     . GLU B 2 121 ? 175.387 174.225 189.845 1.00 54.91  ? 125 GLU F C     1 
ATOM   6916 O O     . GLU B 2 121 ? 174.534 173.546 190.416 1.00 54.91  ? 125 GLU F O     1 
ATOM   6917 C CB    . GLU B 2 121 ? 177.179 173.274 188.374 1.00 54.91  ? 125 GLU F CB    1 
ATOM   6918 C CG    . GLU B 2 121 ? 177.591 172.906 186.971 1.00 54.91  ? 125 GLU F CG    1 
ATOM   6919 C CD    . GLU B 2 121 ? 178.803 172.009 186.934 1.00 54.91  ? 125 GLU F CD    1 
ATOM   6920 O OE1   . GLU B 2 121 ? 179.542 171.969 187.938 1.00 54.91  ? 125 GLU F OE1   1 
ATOM   6921 O OE2   . GLU B 2 121 ? 179.014 171.338 185.901 1.00 54.91  ? 125 GLU F OE2   1 
ATOM   6922 N N     . THR B 2 122 ? 175.984 175.251 190.443 1.00 52.69  ? 126 THR F N     1 
ATOM   6923 C CA    . THR B 2 122 ? 175.630 175.598 191.812 1.00 52.69  ? 126 THR F CA    1 
ATOM   6924 C C     . THR B 2 122 ? 174.244 176.221 191.892 1.00 52.69  ? 126 THR F C     1 
ATOM   6925 O O     . THR B 2 122 ? 173.466 175.893 192.792 1.00 52.69  ? 126 THR F O     1 
ATOM   6926 C CB    . THR B 2 122 ? 176.675 176.540 192.393 1.00 52.69  ? 126 THR F CB    1 
ATOM   6927 O OG1   . THR B 2 122 ? 177.917 175.844 192.508 1.00 52.69  ? 126 THR F OG1   1 
ATOM   6928 C CG2   . THR B 2 122 ? 176.256 177.024 193.754 1.00 52.69  ? 126 THR F CG2   1 
ATOM   6929 N N     . PHE B 2 123 ? 173.910 177.118 190.969 1.00 51.66  ? 127 PHE F N     1 
ATOM   6930 C CA    . PHE B 2 123 ? 172.650 177.836 191.062 1.00 51.66  ? 127 PHE F CA    1 
ATOM   6931 C C     . PHE B 2 123 ? 171.588 177.343 190.094 1.00 51.66  ? 127 PHE F C     1 
ATOM   6932 O O     . PHE B 2 123 ? 170.419 177.689 190.267 1.00 51.66  ? 127 PHE F O     1 
ATOM   6933 C CB    . PHE B 2 123 ? 172.875 179.330 190.840 1.00 51.66  ? 127 PHE F CB    1 
ATOM   6934 C CG    . PHE B 2 123 ? 173.690 179.974 191.907 1.00 51.66  ? 127 PHE F CG    1 
ATOM   6935 C CD1   . PHE B 2 123 ? 173.151 180.221 193.147 1.00 51.66  ? 127 PHE F CD1   1 
ATOM   6936 C CD2   . PHE B 2 123 ? 174.994 180.334 191.673 1.00 51.66  ? 127 PHE F CD2   1 
ATOM   6937 C CE1   . PHE B 2 123 ? 173.893 180.809 194.124 1.00 51.66  ? 127 PHE F CE1   1 
ATOM   6938 C CE2   . PHE B 2 123 ? 175.741 180.926 192.652 1.00 51.66  ? 127 PHE F CE2   1 
ATOM   6939 C CZ    . PHE B 2 123 ? 175.191 181.159 193.878 1.00 51.66  ? 127 PHE F CZ    1 
ATOM   6940 N N     . ASN B 2 124 ? 171.963 176.568 189.083 1.00 53.43  ? 128 ASN F N     1 
ATOM   6941 C CA    . ASN B 2 124 ? 171.010 175.860 188.227 1.00 53.43  ? 128 ASN F CA    1 
ATOM   6942 C C     . ASN B 2 124 ? 170.122 176.804 187.426 1.00 53.43  ? 128 ASN F C     1 
ATOM   6943 O O     . ASN B 2 124 ? 168.979 176.476 187.118 1.00 53.43  ? 128 ASN F O     1 
ATOM   6944 C CB    . ASN B 2 124 ? 170.150 174.897 189.042 1.00 53.43  ? 128 ASN F CB    1 
ATOM   6945 C CG    . ASN B 2 124 ? 170.834 173.580 189.283 1.00 53.43  ? 128 ASN F CG    1 
ATOM   6946 O OD1   . ASN B 2 124 ? 171.416 172.999 188.373 1.00 53.43  ? 128 ASN F OD1   1 
ATOM   6947 N ND2   . ASN B 2 124 ? 170.778 173.101 190.514 1.00 53.43  ? 128 ASN F ND2   1 
ATOM   6948 N N     . VAL B 2 125 ? 170.652 177.965 187.052 1.00 52.04  ? 129 VAL F N     1 
ATOM   6949 C CA    . VAL B 2 125 ? 169.889 178.924 186.257 1.00 52.04  ? 129 VAL F CA    1 
ATOM   6950 C C     . VAL B 2 125 ? 169.517 178.268 184.936 1.00 52.04  ? 129 VAL F C     1 
ATOM   6951 O O     . VAL B 2 125 ? 170.238 177.379 184.468 1.00 52.04  ? 129 VAL F O     1 
ATOM   6952 C CB    . VAL B 2 125 ? 170.673 180.223 186.026 1.00 52.04  ? 129 VAL F CB    1 
ATOM   6953 C CG1   . VAL B 2 125 ? 171.082 180.836 187.336 1.00 52.04  ? 129 VAL F CG1   1 
ATOM   6954 C CG2   . VAL B 2 125 ? 171.881 179.968 185.177 1.00 52.04  ? 129 VAL F CG2   1 
ATOM   6955 N N     . PRO B 2 126 ? 168.398 178.639 184.316 1.00 53.35  ? 130 PRO F N     1 
ATOM   6956 C CA    . PRO B 2 126 ? 168.048 178.018 183.035 1.00 53.35  ? 130 PRO F CA    1 
ATOM   6957 C C     . PRO B 2 126 ? 168.896 178.510 181.883 1.00 53.35  ? 130 PRO F C     1 
ATOM   6958 O O     . PRO B 2 126 ? 169.132 177.753 180.936 1.00 53.35  ? 130 PRO F O     1 
ATOM   6959 C CB    . PRO B 2 126 ? 166.577 178.402 182.858 1.00 53.35  ? 130 PRO F CB    1 
ATOM   6960 C CG    . PRO B 2 126 ? 166.438 179.655 183.605 1.00 53.35  ? 130 PRO F CG    1 
ATOM   6961 C CD    . PRO B 2 126 ? 167.345 179.547 184.786 1.00 53.35  ? 130 PRO F CD    1 
ATOM   6962 N N     . ALA B 2 127 ? 169.361 179.751 181.933 1.00 52.50  ? 131 ALA F N     1 
ATOM   6963 C CA    . ALA B 2 127 ? 170.193 180.309 180.885 1.00 52.50  ? 131 ALA F CA    1 
ATOM   6964 C C     . ALA B 2 127 ? 171.081 181.370 181.505 1.00 52.50  ? 131 ALA F C     1 
ATOM   6965 O O     . ALA B 2 127 ? 170.866 181.789 182.639 1.00 52.50  ? 131 ALA F O     1 
ATOM   6966 C CB    . ALA B 2 127 ? 169.347 180.894 179.757 1.00 52.50  ? 131 ALA F CB    1 
ATOM   6967 N N     . MET B 2 128 ? 172.089 181.803 180.758 1.00 51.93  ? 132 MET F N     1 
ATOM   6968 C CA    . MET B 2 128 ? 172.923 182.893 181.236 1.00 51.93  ? 132 MET F CA    1 
ATOM   6969 C C     . MET B 2 128 ? 173.703 183.468 180.069 1.00 51.93  ? 132 MET F C     1 
ATOM   6970 O O     . MET B 2 128 ? 173.729 182.905 178.977 1.00 51.93  ? 132 MET F O     1 
ATOM   6971 C CB    . MET B 2 128 ? 173.850 182.437 182.363 1.00 51.93  ? 132 MET F CB    1 
ATOM   6972 C CG    . MET B 2 128 ? 174.900 181.423 181.993 1.00 51.93  ? 132 MET F CG    1 
ATOM   6973 S SD    . MET B 2 128 ? 176.391 182.222 181.423 1.00 51.93  ? 132 MET F SD    1 
ATOM   6974 C CE    . MET B 2 128 ? 176.881 183.013 182.940 1.00 51.93  ? 132 MET F CE    1 
ATOM   6975 N N     . TYR B 2 129 ? 174.348 184.600 180.320 1.00 49.26  ? 133 TYR F N     1 
ATOM   6976 C CA    . TYR B 2 129 ? 175.040 185.340 179.281 1.00 49.26  ? 133 TYR F CA    1 
ATOM   6977 C C     . TYR B 2 129 ? 175.985 186.320 179.947 1.00 49.26  ? 133 TYR F C     1 
ATOM   6978 O O     . TYR B 2 129 ? 175.679 186.859 181.007 1.00 49.26  ? 133 TYR F O     1 
ATOM   6979 C CB    . TYR B 2 129 ? 174.044 186.069 178.383 1.00 49.26  ? 133 TYR F CB    1 
ATOM   6980 C CG    . TYR B 2 129 ? 174.664 186.744 177.197 1.00 49.26  ? 133 TYR F CG    1 
ATOM   6981 C CD1   . TYR B 2 129 ? 175.012 186.024 176.074 1.00 49.26  ? 133 TYR F CD1   1 
ATOM   6982 C CD2   . TYR B 2 129 ? 174.890 188.102 177.195 1.00 49.26  ? 133 TYR F CD2   1 
ATOM   6983 C CE1   . TYR B 2 129 ? 175.572 186.637 174.996 1.00 49.26  ? 133 TYR F CE1   1 
ATOM   6984 C CE2   . TYR B 2 129 ? 175.448 188.722 176.118 1.00 49.26  ? 133 TYR F CE2   1 
ATOM   6985 C CZ    . TYR B 2 129 ? 175.788 187.986 175.024 1.00 49.26  ? 133 TYR F CZ    1 
ATOM   6986 O OH    . TYR B 2 129 ? 176.346 188.607 173.945 1.00 49.26  ? 133 TYR F OH    1 
ATOM   6987 N N     . VAL B 2 130 ? 177.138 186.542 179.327 1.00 45.45  ? 134 VAL F N     1 
ATOM   6988 C CA    . VAL B 2 130 ? 178.154 187.437 179.864 1.00 45.45  ? 134 VAL F CA    1 
ATOM   6989 C C     . VAL B 2 130 ? 178.382 188.564 178.870 1.00 45.45  ? 134 VAL F C     1 
ATOM   6990 O O     . VAL B 2 130 ? 178.734 188.314 177.715 1.00 45.45  ? 134 VAL F O     1 
ATOM   6991 C CB    . VAL B 2 130 ? 179.466 186.693 180.152 1.00 45.45  ? 134 VAL F CB    1 
ATOM   6992 C CG1   . VAL B 2 130 ? 180.402 187.580 180.913 1.00 45.45  ? 134 VAL F CG1   1 
ATOM   6993 C CG2   . VAL B 2 130 ? 179.194 185.453 180.940 1.00 45.45  ? 134 VAL F CG2   1 
ATOM   6994 N N     . ALA B 2 131 ? 178.198 189.797 179.317 1.00 41.02  ? 135 ALA F N     1 
ATOM   6995 C CA    . ALA B 2 131 ? 178.278 190.957 178.450 1.00 41.02  ? 135 ALA F CA    1 
ATOM   6996 C C     . ALA B 2 131 ? 179.443 191.841 178.861 1.00 41.02  ? 135 ALA F C     1 
ATOM   6997 O O     . ALA B 2 131 ? 179.969 191.730 179.965 1.00 41.02  ? 135 ALA F O     1 
ATOM   6998 C CB    . ALA B 2 131 ? 176.984 191.762 178.494 1.00 41.02  ? 135 ALA F CB    1 
ATOM   6999 N N     . ILE B 2 132 ? 179.842 192.720 177.971 1.00 39.08  ? 136 ILE F N     1 
ATOM   7000 C CA    . ILE B 2 132 ? 180.928 193.650 178.243 1.00 39.08  ? 136 ILE F CA    1 
ATOM   7001 C C     . ILE B 2 132 ? 180.340 194.920 178.829 1.00 39.08  ? 136 ILE F C     1 
ATOM   7002 O O     . ILE B 2 132 ? 179.281 195.379 178.403 1.00 39.08  ? 136 ILE F O     1 
ATOM   7003 C CB    . ILE B 2 132 ? 181.729 193.942 176.966 1.00 39.08  ? 136 ILE F CB    1 
ATOM   7004 C CG1   . ILE B 2 132 ? 182.244 192.644 176.366 1.00 39.08  ? 136 ILE F CG1   1 
ATOM   7005 C CG2   . ILE B 2 132 ? 182.881 194.857 177.265 1.00 39.08  ? 136 ILE F CG2   1 
ATOM   7006 C CD1   . ILE B 2 132 ? 183.238 191.949 177.224 1.00 39.08  ? 136 ILE F CD1   1 
ATOM   7007 N N     . GLN B 2 133 ? 181.027 195.498 179.806 1.00 39.24  ? 137 GLN F N     1 
ATOM   7008 C CA    . GLN B 2 133 ? 180.463 196.632 180.522 1.00 39.24  ? 137 GLN F CA    1 
ATOM   7009 C C     . GLN B 2 133 ? 180.309 197.851 179.624 1.00 39.24  ? 137 GLN F C     1 
ATOM   7010 O O     . GLN B 2 133 ? 179.321 198.586 179.726 1.00 39.24  ? 137 GLN F O     1 
ATOM   7011 C CB    . GLN B 2 133 ? 181.340 196.958 181.718 1.00 39.24  ? 137 GLN F CB    1 
ATOM   7012 C CG    . GLN B 2 133 ? 181.787 195.741 182.446 1.00 39.24  ? 137 GLN F CG    1 
ATOM   7013 C CD    . GLN B 2 133 ? 182.091 196.009 183.881 1.00 39.24  ? 137 GLN F CD    1 
ATOM   7014 O OE1   . GLN B 2 133 ? 182.599 197.067 184.227 1.00 39.24  ? 137 GLN F OE1   1 
ATOM   7015 N NE2   . GLN B 2 133 ? 181.777 195.056 184.738 1.00 39.24  ? 137 GLN F NE2   1 
ATOM   7016 N N     . ALA B 2 134 ? 181.270 198.082 178.737 1.00 36.81  ? 138 ALA F N     1 
ATOM   7017 C CA    . ALA B 2 134 ? 181.247 199.289 177.926 1.00 36.81  ? 138 ALA F CA    1 
ATOM   7018 C C     . ALA B 2 134 ? 180.104 199.268 176.923 1.00 36.81  ? 138 ALA F C     1 
ATOM   7019 O O     . ALA B 2 134 ? 179.455 200.295 176.685 1.00 36.81  ? 138 ALA F O     1 
ATOM   7020 C CB    . ALA B 2 134 ? 182.582 199.444 177.218 1.00 36.81  ? 138 ALA F CB    1 
ATOM   7021 N N     . VAL B 2 135 ? 179.833 198.110 176.332 1.00 37.24  ? 139 VAL F N     1 
ATOM   7022 C CA    . VAL B 2 135 ? 178.714 198.006 175.406 1.00 37.24  ? 139 VAL F CA    1 
ATOM   7023 C C     . VAL B 2 135 ? 177.412 198.356 176.107 1.00 37.24  ? 139 VAL F C     1 
ATOM   7024 O O     . VAL B 2 135 ? 176.550 199.045 175.548 1.00 37.24  ? 139 VAL F O     1 
ATOM   7025 C CB    . VAL B 2 135 ? 178.664 196.599 174.798 1.00 37.24  ? 139 VAL F CB    1 
ATOM   7026 C CG1   . VAL B 2 135 ? 177.616 196.542 173.730 1.00 37.24  ? 139 VAL F CG1   1 
ATOM   7027 C CG2   . VAL B 2 135 ? 180.011 196.235 174.250 1.00 37.24  ? 139 VAL F CG2   1 
ATOM   7028 N N     . LEU B 2 136 ? 177.249 197.896 177.342 1.00 36.16  ? 140 LEU F N     1 
ATOM   7029 C CA    . LEU B 2 136 ? 176.022 198.178 178.067 1.00 36.16  ? 140 LEU F CA    1 
ATOM   7030 C C     . LEU B 2 136 ? 175.938 199.647 178.449 1.00 36.16  ? 140 LEU F C     1 
ATOM   7031 O O     . LEU B 2 136 ? 174.850 200.232 178.449 1.00 36.16  ? 140 LEU F O     1 
ATOM   7032 C CB    . LEU B 2 136 ? 175.940 197.278 179.289 1.00 36.16  ? 140 LEU F CB    1 
ATOM   7033 C CG    . LEU B 2 136 ? 176.024 195.795 178.963 1.00 36.16  ? 140 LEU F CG    1 
ATOM   7034 C CD1   . LEU B 2 136 ? 175.960 194.965 180.205 1.00 36.16  ? 140 LEU F CD1   1 
ATOM   7035 C CD2   . LEU B 2 136 ? 174.916 195.414 178.045 1.00 36.16  ? 140 LEU F CD2   1 
ATOM   7036 N N     . SER B 2 137 ? 177.071 200.266 178.769 1.00 36.82  ? 141 SER F N     1 
ATOM   7037 C CA    . SER B 2 137 ? 177.059 201.706 178.982 1.00 36.82  ? 141 SER F CA    1 
ATOM   7038 C C     . SER B 2 137 ? 176.546 202.423 177.753 1.00 36.82  ? 141 SER F C     1 
ATOM   7039 O O     . SER B 2 137 ? 175.784 203.389 177.855 1.00 36.82  ? 141 SER F O     1 
ATOM   7040 C CB    . SER B 2 137 ? 178.453 202.207 179.323 1.00 36.82  ? 141 SER F CB    1 
ATOM   7041 O OG    . SER B 2 137 ? 178.898 201.693 180.554 1.00 36.82  ? 141 SER F OG    1 
ATOM   7042 N N     . LEU B 2 138 ? 176.954 201.964 176.577 1.00 38.13  ? 142 LEU F N     1 
ATOM   7043 C CA    . LEU B 2 138 ? 176.580 202.681 175.368 1.00 38.13  ? 142 LEU F CA    1 
ATOM   7044 C C     . LEU B 2 138 ? 175.123 202.431 175.005 1.00 38.13  ? 142 LEU F C     1 
ATOM   7045 O O     . LEU B 2 138 ? 174.481 203.303 174.420 1.00 38.13  ? 142 LEU F O     1 
ATOM   7046 C CB    . LEU B 2 138 ? 177.521 202.298 174.232 1.00 38.13  ? 142 LEU F CB    1 
ATOM   7047 C CG    . LEU B 2 138 ? 177.554 203.274 173.071 1.00 38.13  ? 142 LEU F CG    1 
ATOM   7048 C CD1   . LEU B 2 138 ? 177.994 204.601 173.594 1.00 38.13  ? 142 LEU F CD1   1 
ATOM   7049 C CD2   . LEU B 2 138 ? 178.533 202.803 172.063 1.00 38.13  ? 142 LEU F CD2   1 
ATOM   7050 N N     . TYR B 2 139 ? 174.589 201.251 175.327 1.00 40.18  ? 143 TYR F N     1 
ATOM   7051 C CA    . TYR B 2 139 ? 173.137 201.060 175.295 1.00 40.18  ? 143 TYR F CA    1 
ATOM   7052 C C     . TYR B 2 139 ? 172.421 202.076 176.166 1.00 40.18  ? 143 TYR F C     1 
ATOM   7053 O O     . TYR B 2 139 ? 171.532 202.791 175.701 1.00 40.18  ? 143 TYR F O     1 
ATOM   7054 C CB    . TYR B 2 139 ? 172.760 199.662 175.762 1.00 40.18  ? 143 TYR F CB    1 
ATOM   7055 C CG    . TYR B 2 139 ? 172.634 198.629 174.694 1.00 40.18  ? 143 TYR F CG    1 
ATOM   7056 C CD1   . TYR B 2 139 ? 172.359 198.977 173.398 1.00 40.18  ? 143 TYR F CD1   1 
ATOM   7057 C CD2   . TYR B 2 139 ? 172.781 197.299 174.988 1.00 40.18  ? 143 TYR F CD2   1 
ATOM   7058 C CE1   . TYR B 2 139 ? 172.229 198.026 172.429 1.00 40.18  ? 143 TYR F CE1   1 
ATOM   7059 C CE2   . TYR B 2 139 ? 172.662 196.349 174.027 1.00 40.18  ? 143 TYR F CE2   1 
ATOM   7060 C CZ    . TYR B 2 139 ? 172.385 196.711 172.752 1.00 40.18  ? 143 TYR F CZ    1 
ATOM   7061 O OH    . TYR B 2 139 ? 172.264 195.743 171.791 1.00 40.18  ? 143 TYR F OH    1 
ATOM   7062 N N     . ALA B 2 140 ? 172.781 202.138 177.445 1.00 38.41  ? 144 ALA F N     1 
ATOM   7063 C CA    . ALA B 2 140 ? 172.075 203.020 178.365 1.00 38.41  ? 144 ALA F CA    1 
ATOM   7064 C C     . ALA B 2 140 ? 172.254 204.491 178.031 1.00 38.41  ? 144 ALA F C     1 
ATOM   7065 O O     . ALA B 2 140 ? 171.434 205.307 178.450 1.00 38.41  ? 144 ALA F O     1 
ATOM   7066 C CB    . ALA B 2 140 ? 172.535 202.775 179.793 1.00 38.41  ? 144 ALA F CB    1 
ATOM   7067 N N     . SER B 2 141 ? 173.298 204.854 177.298 1.00 40.52  ? 145 SER F N     1 
ATOM   7068 C CA    . SER B 2 141 ? 173.476 206.251 176.934 1.00 40.52  ? 145 SER F CA    1 
ATOM   7069 C C     . SER B 2 141 ? 172.654 206.672 175.730 1.00 40.52  ? 145 SER F C     1 
ATOM   7070 O O     . SER B 2 141 ? 172.637 207.861 175.407 1.00 40.52  ? 145 SER F O     1 
ATOM   7071 C CB    . SER B 2 141 ? 174.936 206.543 176.640 1.00 40.52  ? 145 SER F CB    1 
ATOM   7072 O OG    . SER B 2 141 ? 175.039 207.766 175.949 1.00 40.52  ? 145 SER F OG    1 
ATOM   7073 N N     . GLY B 2 142 ? 171.990 205.742 175.056 1.00 43.28  ? 146 GLY F N     1 
ATOM   7074 C CA    . GLY B 2 142 ? 171.219 206.094 173.882 1.00 43.28  ? 146 GLY F CA    1 
ATOM   7075 C C     . GLY B 2 142 ? 172.046 206.436 172.668 1.00 43.28  ? 146 GLY F C     1 
ATOM   7076 O O     . GLY B 2 142 ? 171.603 207.216 171.829 1.00 43.28  ? 146 GLY F O     1 
ATOM   7077 N N     . ARG B 2 143 ? 173.241 205.875 172.553 1.00 42.48  ? 147 ARG F N     1 
ATOM   7078 C CA    . ARG B 2 143 ? 174.102 206.059 171.400 1.00 42.48  ? 147 ARG F CA    1 
ATOM   7079 C C     . ARG B 2 143 ? 174.214 204.749 170.652 1.00 42.48  ? 147 ARG F C     1 
ATOM   7080 O O     . ARG B 2 143 ? 173.800 203.694 171.125 1.00 42.48  ? 147 ARG F O     1 
ATOM   7081 C CB    . ARG B 2 143 ? 175.508 206.513 171.793 1.00 42.48  ? 147 ARG F CB    1 
ATOM   7082 C CG    . ARG B 2 143 ? 175.576 207.684 172.695 1.00 42.48  ? 147 ARG F CG    1 
ATOM   7083 C CD    . ARG B 2 143 ? 174.996 208.869 172.028 1.00 42.48  ? 147 ARG F CD    1 
ATOM   7084 N NE    . ARG B 2 143 ? 174.544 209.843 173.000 1.00 42.48  ? 147 ARG F NE    1 
ATOM   7085 C CZ    . ARG B 2 143 ? 175.308 210.809 173.467 1.00 42.48  ? 147 ARG F CZ    1 
ATOM   7086 N NH1   . ARG B 2 143 ? 176.545 210.915 173.036 1.00 42.48  ? 147 ARG F NH1   1 
ATOM   7087 N NH2   . ARG B 2 143 ? 174.829 211.669 174.344 1.00 42.48  ? 147 ARG F NH2   1 
ATOM   7088 N N     . THR B 2 144 ? 174.792 204.828 169.470 1.00 41.07  ? 148 THR F N     1 
ATOM   7089 C CA    . THR B 2 144 ? 175.221 203.645 168.764 1.00 41.07  ? 148 THR F CA    1 
ATOM   7090 C C     . THR B 2 144 ? 176.654 203.762 168.287 1.00 41.07  ? 148 THR F C     1 
ATOM   7091 O O     . THR B 2 144 ? 177.217 202.760 167.843 1.00 41.07  ? 148 THR F O     1 
ATOM   7092 C CB    . THR B 2 144 ? 174.293 203.356 167.580 1.00 41.07  ? 148 THR F CB    1 
ATOM   7093 O OG1   . THR B 2 144 ? 174.555 202.051 167.069 1.00 41.07  ? 148 THR F OG1   1 
ATOM   7094 C CG2   . THR B 2 144 ? 174.497 204.375 166.480 1.00 41.07  ? 148 THR F CG2   1 
ATOM   7095 N N     . THR B 2 145 ? 177.256 204.942 168.365 1.00 37.35  ? 149 THR F N     1 
ATOM   7096 C CA    . THR B 2 145 ? 178.683 205.142 168.198 1.00 37.35  ? 149 THR F CA    1 
ATOM   7097 C C     . THR B 2 145 ? 179.222 205.779 169.465 1.00 37.35  ? 149 THR F C     1 
ATOM   7098 O O     . THR B 2 145 ? 178.474 206.116 170.372 1.00 37.35  ? 149 THR F O     1 
ATOM   7099 C CB    . THR B 2 145 ? 179.005 206.044 167.007 1.00 37.35  ? 149 THR F CB    1 
ATOM   7100 O OG1   . THR B 2 145 ? 178.675 207.389 167.337 1.00 37.35  ? 149 THR F OG1   1 
ATOM   7101 C CG2   . THR B 2 145 ? 178.185 205.661 165.824 1.00 37.35  ? 149 THR F CG2   1 
ATOM   7102 N N     . GLY B 2 146 ? 180.530 205.964 169.518 1.00 34.04  ? 150 GLY F N     1 
ATOM   7103 C CA    . GLY B 2 146 ? 181.123 206.641 170.649 1.00 34.04  ? 150 GLY F CA    1 
ATOM   7104 C C     . GLY B 2 146 ? 182.197 205.840 171.337 1.00 34.04  ? 150 GLY F C     1 
ATOM   7105 O O     . GLY B 2 146 ? 182.166 204.613 171.317 1.00 34.04  ? 150 GLY F O     1 
ATOM   7106 N N     . ILE B 2 147 ? 183.159 206.522 171.939 1.00 31.99  ? 151 ILE F N     1 
ATOM   7107 C CA    . ILE B 2 147 ? 184.219 205.885 172.703 1.00 31.99  ? 151 ILE F CA    1 
ATOM   7108 C C     . ILE B 2 147 ? 183.870 205.996 174.176 1.00 31.99  ? 151 ILE F C     1 
ATOM   7109 O O     . ILE B 2 147 ? 183.765 207.096 174.723 1.00 31.99  ? 151 ILE F O     1 
ATOM   7110 C CB    . ILE B 2 147 ? 185.585 206.510 172.392 1.00 31.99  ? 151 ILE F CB    1 
ATOM   7111 C CG1   . ILE B 2 147 ? 186.675 205.818 173.185 1.00 31.99  ? 151 ILE F CG1   1 
ATOM   7112 C CG2   . ILE B 2 147 ? 185.590 207.997 172.619 1.00 31.99  ? 151 ILE F CG2   1 
ATOM   7113 C CD1   . ILE B 2 147 ? 188.027 206.194 172.742 1.00 31.99  ? 151 ILE F CD1   1 
ATOM   7114 N N     . VAL B 2 148 ? 183.674 204.865 174.825 1.00 31.96  ? 152 VAL F N     1 
ATOM   7115 C CA    . VAL B 2 148 ? 183.194 204.831 176.195 1.00 31.96  ? 152 VAL F CA    1 
ATOM   7116 C C     . VAL B 2 148 ? 184.354 204.556 177.137 1.00 31.96  ? 152 VAL F C     1 
ATOM   7117 O O     . VAL B 2 148 ? 185.160 203.654 176.898 1.00 31.96  ? 152 VAL F O     1 
ATOM   7118 C CB    . VAL B 2 148 ? 182.073 203.796 176.342 1.00 31.96  ? 152 VAL F CB    1 
ATOM   7119 C CG1   . VAL B 2 148 ? 182.495 202.550 175.716 1.00 31.96  ? 152 VAL F CG1   1 
ATOM   7120 C CG2   . VAL B 2 148 ? 181.784 203.539 177.783 1.00 31.96  ? 152 VAL F CG2   1 
ATOM   7121 N N     . LEU B 2 149 ? 184.454 205.357 178.192 1.00 33.00  ? 153 LEU F N     1 
ATOM   7122 C CA    . LEU B 2 149 ? 185.489 205.244 179.215 1.00 33.00  ? 153 LEU F CA    1 
ATOM   7123 C C     . LEU B 2 149 ? 184.816 204.806 180.506 1.00 33.00  ? 153 LEU F C     1 
ATOM   7124 O O     . LEU B 2 149 ? 184.171 205.611 181.172 1.00 33.00  ? 153 LEU F O     1 
ATOM   7125 C CB    . LEU B 2 149 ? 186.208 206.570 179.401 1.00 33.00  ? 153 LEU F CB    1 
ATOM   7126 C CG    . LEU B 2 149 ? 187.128 206.639 180.613 1.00 33.00  ? 153 LEU F CG    1 
ATOM   7127 C CD1   . LEU B 2 149 ? 188.389 205.865 180.374 1.00 33.00  ? 153 LEU F CD1   1 
ATOM   7128 C CD2   . LEU B 2 149 ? 187.461 208.060 180.936 1.00 33.00  ? 153 LEU F CD2   1 
ATOM   7129 N N     . ASP B 2 150 ? 184.958 203.538 180.857 1.00 36.56  ? 154 ASP F N     1 
ATOM   7130 C CA    . ASP B 2 150 ? 184.239 202.955 181.984 1.00 36.56  ? 154 ASP F CA    1 
ATOM   7131 C C     . ASP B 2 150 ? 185.206 202.755 183.138 1.00 36.56  ? 154 ASP F C     1 
ATOM   7132 O O     . ASP B 2 150 ? 185.921 201.759 183.191 1.00 36.56  ? 154 ASP F O     1 
ATOM   7133 C CB    . ASP B 2 150 ? 183.594 201.637 181.580 1.00 36.56  ? 154 ASP F CB    1 
ATOM   7134 C CG    . ASP B 2 150 ? 182.592 201.134 182.600 1.00 36.56  ? 154 ASP F CG    1 
ATOM   7135 O OD1   . ASP B 2 150 ? 182.853 201.221 183.813 1.00 36.56  ? 154 ASP F OD1   1 
ATOM   7136 O OD2   . ASP B 2 150 ? 181.529 200.641 182.185 1.00 36.56  ? 154 ASP F OD2   1 
ATOM   7137 N N     . SER B 2 151 ? 185.187 203.666 184.089 1.00 37.15  ? 155 SER F N     1 
ATOM   7138 C CA    . SER B 2 151 ? 186.097 203.633 185.225 1.00 37.15  ? 155 SER F CA    1 
ATOM   7139 C C     . SER B 2 151 ? 185.337 203.086 186.423 1.00 37.15  ? 155 SER F C     1 
ATOM   7140 O O     . SER B 2 151 ? 184.569 203.802 187.062 1.00 37.15  ? 155 SER F O     1 
ATOM   7141 C CB    . SER B 2 151 ? 186.656 205.019 185.505 1.00 37.15  ? 155 SER F CB    1 
ATOM   7142 O OG    . SER B 2 151 ? 187.837 204.944 186.266 1.00 37.15  ? 155 SER F OG    1 
ATOM   7143 N N     . GLY B 2 152 ? 185.551 201.820 186.729 1.00 39.67  ? 156 GLY F N     1 
ATOM   7144 C CA    . GLY B 2 152 ? 184.877 201.219 187.855 1.00 39.67  ? 156 GLY F CA    1 
ATOM   7145 C C     . GLY B 2 152 ? 185.638 201.387 189.149 1.00 39.67  ? 156 GLY F C     1 
ATOM   7146 O O     . GLY B 2 152 ? 186.011 202.500 189.518 1.00 39.67  ? 156 GLY F O     1 
ATOM   7147 N N     . ASP B 2 153 ? 185.860 200.283 189.856 1.00 42.39  ? 157 ASP F N     1 
ATOM   7148 C CA    . ASP B 2 153 ? 186.625 200.296 191.088 1.00 42.39  ? 157 ASP F CA    1 
ATOM   7149 C C     . ASP B 2 153 ? 187.891 199.464 191.020 1.00 42.39  ? 157 ASP F C     1 
ATOM   7150 O O     . ASP B 2 153 ? 188.783 199.660 191.843 1.00 42.39  ? 157 ASP F O     1 
ATOM   7151 C CB    . ASP B 2 153 ? 185.753 199.800 192.244 1.00 42.39  ? 157 ASP F CB    1 
ATOM   7152 C CG    . ASP B 2 153 ? 186.426 199.922 193.582 1.00 42.39  ? 157 ASP F CG    1 
ATOM   7153 O OD1   . ASP B 2 153 ? 187.257 200.830 193.751 1.00 42.39  ? 157 ASP F OD1   1 
ATOM   7154 O OD2   . ASP B 2 153 ? 186.122 199.109 194.475 1.00 42.39  ? 157 ASP F OD2   1 
ATOM   7155 N N     . GLY B 2 154 ? 187.997 198.550 190.069 1.00 42.64  ? 158 GLY F N     1 
ATOM   7156 C CA    . GLY B 2 154 ? 189.238 197.839 189.878 1.00 42.64  ? 158 GLY F CA    1 
ATOM   7157 C C     . GLY B 2 154 ? 189.928 198.164 188.573 1.00 42.64  ? 158 GLY F C     1 
ATOM   7158 O O     . GLY B 2 154 ? 191.155 198.222 188.521 1.00 42.64  ? 158 GLY F O     1 
ATOM   7159 N N     . VAL B 2 155 ? 189.162 198.400 187.517 1.00 38.33  ? 159 VAL F N     1 
ATOM   7160 C CA    . VAL B 2 155 ? 189.708 198.492 186.172 1.00 38.33  ? 159 VAL F CA    1 
ATOM   7161 C C     . VAL B 2 155 ? 189.098 199.689 185.460 1.00 38.33  ? 159 VAL F C     1 
ATOM   7162 O O     . VAL B 2 155 ? 187.932 200.026 185.675 1.00 38.33  ? 159 VAL F O     1 
ATOM   7163 C CB    . VAL B 2 155 ? 189.456 197.184 185.398 1.00 38.33  ? 159 VAL F CB    1 
ATOM   7164 C CG1   . VAL B 2 155 ? 188.008 196.831 185.436 1.00 38.33  ? 159 VAL F CG1   1 
ATOM   7165 C CG2   . VAL B 2 155 ? 189.908 197.303 183.982 1.00 38.33  ? 159 VAL F CG2   1 
ATOM   7166 N N     . THR B 2 156 ? 189.899 200.347 184.633 1.00 35.34  ? 160 THR F N     1 
ATOM   7167 C CA    . THR B 2 156 ? 189.452 201.391 183.727 1.00 35.34  ? 160 THR F CA    1 
ATOM   7168 C C     . THR B 2 156 ? 189.691 200.921 182.303 1.00 35.34  ? 160 THR F C     1 
ATOM   7169 O O     . THR B 2 156 ? 190.716 200.306 182.019 1.00 35.34  ? 160 THR F O     1 
ATOM   7170 C CB    . THR B 2 156 ? 190.216 202.685 183.974 1.00 35.34  ? 160 THR F CB    1 
ATOM   7171 O OG1   . THR B 2 156 ? 190.107 203.042 185.351 1.00 35.34  ? 160 THR F OG1   1 
ATOM   7172 C CG2   . THR B 2 156 ? 189.671 203.802 183.138 1.00 35.34  ? 160 THR F CG2   1 
ATOM   7173 N N     . HIS B 2 157 ? 188.759 201.198 181.399 1.00 34.55  ? 161 HIS F N     1 
ATOM   7174 C CA    . HIS B 2 157 ? 188.982 200.784 180.026 1.00 34.55  ? 161 HIS F CA    1 
ATOM   7175 C C     . HIS B 2 157 ? 188.243 201.690 179.057 1.00 34.55  ? 161 HIS F C     1 
ATOM   7176 O O     . HIS B 2 157 ? 187.223 202.288 179.388 1.00 34.55  ? 161 HIS F O     1 
ATOM   7177 C CB    . HIS B 2 157 ? 188.574 199.331 179.815 1.00 34.55  ? 161 HIS F CB    1 
ATOM   7178 C CG    . HIS B 2 157 ? 187.143 199.046 180.115 1.00 34.55  ? 161 HIS F CG    1 
ATOM   7179 N ND1   . HIS B 2 157 ? 186.726 198.531 181.320 1.00 34.55  ? 161 HIS F ND1   1 
ATOM   7180 C CD2   . HIS B 2 157 ? 186.034 199.161 179.353 1.00 34.55  ? 161 HIS F CD2   1 
ATOM   7181 C CE1   . HIS B 2 157 ? 185.418 198.358 181.293 1.00 34.55  ? 161 HIS F CE1   1 
ATOM   7182 N NE2   . HIS B 2 157 ? 184.974 198.731 180.110 1.00 34.55  ? 161 HIS F NE2   1 
ATOM   7183 N N     . ASN B 2 158 ? 188.791 201.787 177.849 1.00 34.71  ? 162 ASN F N     1 
ATOM   7184 C CA    . ASN B 2 158 ? 188.169 202.457 176.716 1.00 34.71  ? 162 ASN F CA    1 
ATOM   7185 C C     . ASN B 2 158 ? 187.734 201.413 175.709 1.00 34.71  ? 162 ASN F C     1 
ATOM   7186 O O     . ASN B 2 158 ? 188.468 200.466 175.442 1.00 34.71  ? 162 ASN F O     1 
ATOM   7187 C CB    . ASN B 2 158 ? 189.134 203.414 176.030 1.00 34.71  ? 162 ASN F CB    1 
ATOM   7188 C CG    . ASN B 2 158 ? 189.765 204.380 176.981 1.00 34.71  ? 162 ASN F CG    1 
ATOM   7189 O OD1   . ASN B 2 158 ? 190.632 204.016 177.763 1.00 34.71  ? 162 ASN F OD1   1 
ATOM   7190 N ND2   . ASN B 2 158 ? 189.343 205.628 176.916 1.00 34.71  ? 162 ASN F ND2   1 
ATOM   7191 N N     . VAL B 2 159 ? 186.545 201.574 175.152 1.00 32.24  ? 163 VAL F N     1 
ATOM   7192 C CA    . VAL B 2 159 ? 186.086 200.669 174.106 1.00 32.24  ? 163 VAL F CA    1 
ATOM   7193 C C     . VAL B 2 159 ? 185.452 201.497 173.003 1.00 32.24  ? 163 VAL F C     1 
ATOM   7194 O O     . VAL B 2 159 ? 184.309 201.938 173.154 1.00 32.24  ? 163 VAL F O     1 
ATOM   7195 C CB    . VAL B 2 159 ? 185.092 199.634 174.644 1.00 32.24  ? 163 VAL F CB    1 
ATOM   7196 C CG1   . VAL B 2 159 ? 184.517 198.832 173.514 1.00 32.24  ? 163 VAL F CG1   1 
ATOM   7197 C CG2   . VAL B 2 159 ? 185.767 198.722 175.617 1.00 32.24  ? 163 VAL F CG2   1 
ATOM   7198 N N     . PRO B 2 160 ? 186.138 201.739 171.890 1.00 31.89  ? 164 PRO F N     1 
ATOM   7199 C CA    . PRO B 2 160 ? 185.542 202.543 170.822 1.00 31.89  ? 164 PRO F CA    1 
ATOM   7200 C C     . PRO B 2 160 ? 184.586 201.710 169.987 1.00 31.89  ? 164 PRO F C     1 
ATOM   7201 O O     . PRO B 2 160 ? 184.947 200.654 169.474 1.00 31.89  ? 164 PRO F O     1 
ATOM   7202 C CB    . PRO B 2 160 ? 186.750 202.995 170.008 1.00 31.89  ? 164 PRO F CB    1 
ATOM   7203 C CG    . PRO B 2 160 ? 187.733 201.961 170.235 1.00 31.89  ? 164 PRO F CG    1 
ATOM   7204 C CD    . PRO B 2 160 ? 187.542 201.428 171.608 1.00 31.89  ? 164 PRO F CD    1 
ATOM   7205 N N     . ILE B 2 161 ? 183.360 202.193 169.860 1.00 35.08  ? 165 ILE F N     1 
ATOM   7206 C CA    . ILE B 2 161 ? 182.317 201.536 169.092 1.00 35.08  ? 165 ILE F CA    1 
ATOM   7207 C C     . ILE B 2 161 ? 181.820 202.516 168.049 1.00 35.08  ? 165 ILE F C     1 
ATOM   7208 O O     . ILE B 2 161 ? 181.609 203.692 168.349 1.00 35.08  ? 165 ILE F O     1 
ATOM   7209 C CB    . ILE B 2 161 ? 181.167 201.075 170.000 1.00 35.08  ? 165 ILE F CB    1 
ATOM   7210 C CG1   . ILE B 2 161 ? 181.666 200.017 170.965 1.00 35.08  ? 165 ILE F CG1   1 
ATOM   7211 C CG2   . ILE B 2 161 ? 180.034 200.533 169.191 1.00 35.08  ? 165 ILE F CG2   1 
ATOM   7212 C CD1   . ILE B 2 161 ? 180.616 199.515 171.877 1.00 35.08  ? 165 ILE F CD1   1 
ATOM   7213 N N     . TYR B 2 162 ? 181.655 202.045 166.822 1.00 38.91  ? 166 TYR F N     1 
ATOM   7214 C CA    . TYR B 2 162 ? 181.135 202.872 165.745 1.00 38.91  ? 166 TYR F CA    1 
ATOM   7215 C C     . TYR B 2 162 ? 180.038 202.110 165.034 1.00 38.91  ? 166 TYR F C     1 
ATOM   7216 O O     . TYR B 2 162 ? 180.279 201.021 164.512 1.00 38.91  ? 166 TYR F O     1 
ATOM   7217 C CB    . TYR B 2 162 ? 182.230 203.261 164.763 1.00 38.91  ? 166 TYR F CB    1 
ATOM   7218 C CG    . TYR B 2 162 ? 181.744 204.127 163.638 1.00 38.91  ? 166 TYR F CG    1 
ATOM   7219 C CD1   . TYR B 2 162 ? 181.656 205.492 163.783 1.00 38.91  ? 166 TYR F CD1   1 
ATOM   7220 C CD2   . TYR B 2 162 ? 181.376 203.580 162.429 1.00 38.91  ? 166 TYR F CD2   1 
ATOM   7221 C CE1   . TYR B 2 162 ? 181.217 206.281 162.761 1.00 38.91  ? 166 TYR F CE1   1 
ATOM   7222 C CE2   . TYR B 2 162 ? 180.937 204.362 161.404 1.00 38.91  ? 166 TYR F CE2   1 
ATOM   7223 C CZ    . TYR B 2 162 ? 180.862 205.710 161.573 1.00 38.91  ? 166 TYR F CZ    1 
ATOM   7224 O OH    . TYR B 2 162 ? 180.420 206.502 160.547 1.00 38.91  ? 166 TYR F OH    1 
ATOM   7225 N N     . GLU B 2 163 ? 178.837 202.669 165.036 1.00 42.92  ? 167 GLU F N     1 
ATOM   7226 C CA    . GLU B 2 163 ? 177.717 202.135 164.281 1.00 42.92  ? 167 GLU F CA    1 
ATOM   7227 C C     . GLU B 2 163 ? 177.348 200.731 164.728 1.00 42.92  ? 167 GLU F C     1 
ATOM   7228 O O     . GLU B 2 163 ? 176.799 199.951 163.956 1.00 42.92  ? 167 GLU F O     1 
ATOM   7229 C CB    . GLU B 2 163 ? 178.018 202.151 162.785 1.00 42.92  ? 167 GLU F CB    1 
ATOM   7230 C CG    . GLU B 2 163 ? 176.819 202.414 161.919 1.00 42.92  ? 167 GLU F CG    1 
ATOM   7231 C CD    . GLU B 2 163 ? 176.342 203.839 162.022 1.00 42.92  ? 167 GLU F CD    1 
ATOM   7232 O OE1   . GLU B 2 163 ? 177.194 204.741 162.131 1.00 42.92  ? 167 GLU F OE1   1 
ATOM   7233 O OE2   . GLU B 2 163 ? 175.114 204.058 162.002 1.00 42.92  ? 167 GLU F OE2   1 
ATOM   7234 N N     . GLY B 2 164 ? 177.635 200.395 165.972 1.00 41.80  ? 168 GLY F N     1 
ATOM   7235 C CA    . GLY B 2 164 ? 177.356 199.071 166.469 1.00 41.80  ? 168 GLY F CA    1 
ATOM   7236 C C     . GLY B 2 164 ? 178.467 198.066 166.290 1.00 41.80  ? 168 GLY F C     1 
ATOM   7237 O O     . GLY B 2 164 ? 178.332 196.934 166.758 1.00 41.80  ? 168 GLY F O     1 
ATOM   7238 N N     . TYR B 2 165 ? 179.559 198.437 165.637 1.00 40.41  ? 169 TYR F N     1 
ATOM   7239 C CA    . TYR B 2 165 ? 180.714 197.570 165.477 1.00 40.41  ? 169 TYR F CA    1 
ATOM   7240 C C     . TYR B 2 165 ? 181.814 198.051 166.403 1.00 40.41  ? 169 TYR F C     1 
ATOM   7241 O O     . TYR B 2 165 ? 182.119 199.243 166.438 1.00 40.41  ? 169 TYR F O     1 
ATOM   7242 C CB    . TYR B 2 165 ? 181.213 197.571 164.036 1.00 40.41  ? 169 TYR F CB    1 
ATOM   7243 C CG    . TYR B 2 165 ? 180.255 196.982 163.050 1.00 40.41  ? 169 TYR F CG    1 
ATOM   7244 C CD1   . TYR B 2 165 ? 180.275 195.640 162.765 1.00 40.41  ? 169 TYR F CD1   1 
ATOM   7245 C CD2   . TYR B 2 165 ? 179.335 197.770 162.400 1.00 40.41  ? 169 TYR F CD2   1 
ATOM   7246 C CE1   . TYR B 2 165 ? 179.408 195.102 161.872 1.00 40.41  ? 169 TYR F CE1   1 
ATOM   7247 C CE2   . TYR B 2 165 ? 178.464 197.239 161.504 1.00 40.41  ? 169 TYR F CE2   1 
ATOM   7248 C CZ    . TYR B 2 165 ? 178.506 195.904 161.243 1.00 40.41  ? 169 TYR F CZ    1 
ATOM   7249 O OH    . TYR B 2 165 ? 177.638 195.357 160.339 1.00 40.41  ? 169 TYR F OH    1 
ATOM   7250 N N     . ALA B 2 166 ? 182.401 197.132 167.150 1.00 37.69  ? 170 ALA F N     1 
ATOM   7251 C CA    . ALA B 2 166 ? 183.467 197.475 168.072 1.00 37.69  ? 170 ALA F CA    1 
ATOM   7252 C C     . ALA B 2 166 ? 184.825 197.203 167.445 1.00 37.69  ? 170 ALA F C     1 
ATOM   7253 O O     . ALA B 2 166 ? 185.006 196.241 166.702 1.00 37.69  ? 170 ALA F O     1 
ATOM   7254 C CB    . ALA B 2 166 ? 183.330 196.686 169.369 1.00 37.69  ? 170 ALA F CB    1 
ATOM   7255 N N     . LEU B 2 167 ? 185.790 198.049 167.785 1.00 34.93  ? 171 LEU F N     1 
ATOM   7256 C CA    . LEU B 2 167 ? 187.134 198.018 167.223 1.00 34.93  ? 171 LEU F CA    1 
ATOM   7257 C C     . LEU B 2 167 ? 188.034 197.337 168.242 1.00 34.93  ? 171 LEU F C     1 
ATOM   7258 O O     . LEU B 2 167 ? 188.638 198.013 169.080 1.00 34.93  ? 171 LEU F O     1 
ATOM   7259 C CB    . LEU B 2 167 ? 187.621 199.441 166.950 1.00 34.93  ? 171 LEU F CB    1 
ATOM   7260 C CG    . LEU B 2 167 ? 187.169 200.306 165.775 1.00 34.93  ? 171 LEU F CG    1 
ATOM   7261 C CD1   . LEU B 2 167 ? 187.640 199.729 164.493 1.00 34.93  ? 171 LEU F CD1   1 
ATOM   7262 C CD2   . LEU B 2 167 ? 185.679 200.471 165.752 1.00 34.93  ? 171 LEU F CD2   1 
ATOM   7263 N N     . PRO B 2 168 ? 188.176 196.013 168.211 1.00 34.79  ? 172 PRO F N     1 
ATOM   7264 C CA    . PRO B 2 168 ? 188.853 195.337 169.321 1.00 34.79  ? 172 PRO F CA    1 
ATOM   7265 C C     . PRO B 2 168 ? 190.319 195.670 169.426 1.00 34.79  ? 172 PRO F C     1 
ATOM   7266 O O     . PRO B 2 168 ? 190.869 195.672 170.529 1.00 34.79  ? 172 PRO F O     1 
ATOM   7267 C CB    . PRO B 2 168 ? 188.638 193.853 169.009 1.00 34.79  ? 172 PRO F CB    1 
ATOM   7268 C CG    . PRO B 2 168 ? 187.615 193.815 167.967 1.00 34.79  ? 172 PRO F CG    1 
ATOM   7269 C CD    . PRO B 2 168 ? 187.773 195.053 167.182 1.00 34.79  ? 172 PRO F CD    1 
ATOM   7270 N N     . HIS B 2 169 ? 190.979 195.946 168.314 1.00 35.07  ? 173 HIS F N     1 
ATOM   7271 C CA    . HIS B 2 169 ? 192.384 196.293 168.371 1.00 35.07  ? 173 HIS F CA    1 
ATOM   7272 C C     . HIS B 2 169 ? 192.627 197.640 169.025 1.00 35.07  ? 173 HIS F C     1 
ATOM   7273 O O     . HIS B 2 169 ? 193.777 197.963 169.322 1.00 35.07  ? 173 HIS F O     1 
ATOM   7274 C CB    . HIS B 2 169 ? 192.959 196.289 166.965 1.00 35.07  ? 173 HIS F CB    1 
ATOM   7275 C CG    . HIS B 2 169 ? 192.353 197.319 166.071 1.00 35.07  ? 173 HIS F CG    1 
ATOM   7276 N ND1   . HIS B 2 169 ? 193.006 198.480 165.727 1.00 35.07  ? 173 HIS F ND1   1 
ATOM   7277 C CD2   . HIS B 2 169 ? 191.149 197.369 165.458 1.00 35.07  ? 173 HIS F CD2   1 
ATOM   7278 C CE1   . HIS B 2 169 ? 192.232 199.201 164.940 1.00 35.07  ? 173 HIS F CE1   1 
ATOM   7279 N NE2   . HIS B 2 169 ? 191.099 198.549 164.761 1.00 35.07  ? 173 HIS F NE2   1 
ATOM   7280 N N     . ALA B 2 170 ? 191.587 198.431 169.259 1.00 33.88  ? 174 ALA F N     1 
ATOM   7281 C CA    . ALA B 2 170 ? 191.734 199.739 169.872 1.00 33.88  ? 174 ALA F CA    1 
ATOM   7282 C C     . ALA B 2 170 ? 191.253 199.759 171.311 1.00 33.88  ? 174 ALA F C     1 
ATOM   7283 O O     . ALA B 2 170 ? 191.240 200.820 171.933 1.00 33.88  ? 174 ALA F O     1 
ATOM   7284 C CB    . ALA B 2 170 ? 190.990 200.791 169.059 1.00 33.88  ? 174 ALA F CB    1 
ATOM   7285 N N     . ILE B 2 171 ? 190.857 198.614 171.852 1.00 32.48  ? 175 ILE F N     1 
ATOM   7286 C CA    . ILE B 2 171 ? 190.436 198.547 173.240 1.00 32.48  ? 175 ILE F CA    1 
ATOM   7287 C C     . ILE B 2 171 ? 191.652 198.682 174.135 1.00 32.48  ? 175 ILE F C     1 
ATOM   7288 O O     . ILE B 2 171 ? 192.637 197.954 173.983 1.00 32.48  ? 175 ILE F O     1 
ATOM   7289 C CB    . ILE B 2 171 ? 189.700 197.234 173.514 1.00 32.48  ? 175 ILE F CB    1 
ATOM   7290 C CG1   . ILE B 2 171 ? 188.349 197.232 172.822 1.00 32.48  ? 175 ILE F CG1   1 
ATOM   7291 C CG2   . ILE B 2 171 ? 189.532 197.039 174.983 1.00 32.48  ? 175 ILE F CG2   1 
ATOM   7292 C CD1   . ILE B 2 171 ? 187.631 195.945 172.957 1.00 32.48  ? 175 ILE F CD1   1 
ATOM   7293 N N     . MET B 2 172 ? 191.598 199.621 175.062 1.00 37.11  ? 176 MET F N     1 
ATOM   7294 C CA    . MET B 2 172 ? 192.669 199.835 176.015 1.00 37.11  ? 176 MET F CA    1 
ATOM   7295 C C     . MET B 2 172 ? 192.136 199.573 177.409 1.00 37.11  ? 176 MET F C     1 
ATOM   7296 O O     . MET B 2 172 ? 191.002 199.925 177.720 1.00 37.11  ? 176 MET F O     1 
ATOM   7297 C CB    . MET B 2 172 ? 193.225 201.243 175.904 1.00 37.11  ? 176 MET F CB    1 
ATOM   7298 C CG    . MET B 2 172 ? 193.678 201.568 174.501 1.00 37.11  ? 176 MET F CG    1 
ATOM   7299 S SD    . MET B 2 172 ? 194.848 202.920 174.389 1.00 37.11  ? 176 MET F SD    1 
ATOM   7300 C CE    . MET B 2 172 ? 196.207 202.250 175.318 1.00 37.11  ? 176 MET F CE    1 
ATOM   7301 N N     . ARG B 2 173 ? 192.943 198.926 178.233 1.00 36.01  ? 177 ARG F N     1 
ATOM   7302 C CA    . ARG B 2 173 ? 192.559 198.603 179.593 1.00 36.01  ? 177 ARG F CA    1 
ATOM   7303 C C     . ARG B 2 173 ? 193.662 199.061 180.525 1.00 36.01  ? 177 ARG F C     1 
ATOM   7304 O O     . ARG B 2 173 ? 194.843 198.856 180.241 1.00 36.01  ? 177 ARG F O     1 
ATOM   7305 C CB    . ARG B 2 173 ? 192.309 197.115 179.755 1.00 36.01  ? 177 ARG F CB    1 
ATOM   7306 C CG    . ARG B 2 173 ? 192.422 196.641 181.152 1.00 36.01  ? 177 ARG F CG    1 
ATOM   7307 C CD    . ARG B 2 173 ? 191.732 195.329 181.310 1.00 36.01  ? 177 ARG F CD    1 
ATOM   7308 N NE    . ARG B 2 173 ? 192.095 194.686 182.561 1.00 36.01  ? 177 ARG F NE    1 
ATOM   7309 C CZ    . ARG B 2 173 ? 191.368 193.750 183.147 1.00 36.01  ? 177 ARG F CZ    1 
ATOM   7310 N NH1   . ARG B 2 173 ? 190.240 193.352 182.600 1.00 36.01  ? 177 ARG F NH1   1 
ATOM   7311 N NH2   . ARG B 2 173 ? 191.763 193.219 184.283 1.00 36.01  ? 177 ARG F NH2   1 
ATOM   7312 N N     . LEU B 2 174 ? 193.279 199.694 181.621 1.00 38.14  ? 178 LEU F N     1 
ATOM   7313 C CA    . LEU B 2 174 ? 194.219 200.242 182.581 1.00 38.14  ? 178 LEU F CA    1 
ATOM   7314 C C     . LEU B 2 174 ? 193.806 199.774 183.963 1.00 38.14  ? 178 LEU F C     1 
ATOM   7315 O O     . LEU B 2 174 ? 192.620 199.807 184.295 1.00 38.14  ? 178 LEU F O     1 
ATOM   7316 C CB    . LEU B 2 174 ? 194.223 201.757 182.501 1.00 38.14  ? 178 LEU F CB    1 
ATOM   7317 C CG    . LEU B 2 174 ? 195.254 202.449 183.363 1.00 38.14  ? 178 LEU F CG    1 
ATOM   7318 C CD1   . LEU B 2 174 ? 196.611 201.905 183.027 1.00 38.14  ? 178 LEU F CD1   1 
ATOM   7319 C CD2   . LEU B 2 174 ? 195.196 203.941 183.123 1.00 38.14  ? 178 LEU F CD2   1 
ATOM   7320 N N     . ASP B 2 175 ? 194.767 199.327 184.764 1.00 41.36  ? 179 ASP F N     1 
ATOM   7321 C CA    . ASP B 2 175 ? 194.464 198.782 186.078 1.00 41.36  ? 179 ASP F CA    1 
ATOM   7322 C C     . ASP B 2 175 ? 194.560 199.813 187.189 1.00 41.36  ? 179 ASP F C     1 
ATOM   7323 O O     . ASP B 2 175 ? 194.972 199.478 188.301 1.00 41.36  ? 179 ASP F O     1 
ATOM   7324 C CB    . ASP B 2 175 ? 195.370 197.597 186.385 1.00 41.36  ? 179 ASP F CB    1 
ATOM   7325 C CG    . ASP B 2 175 ? 194.776 196.290 185.928 1.00 41.36  ? 179 ASP F CG    1 
ATOM   7326 O OD1   . ASP B 2 175 ? 193.570 196.268 185.626 1.00 41.36  ? 179 ASP F OD1   1 
ATOM   7327 O OD2   . ASP B 2 175 ? 195.505 195.282 185.883 1.00 41.36  ? 179 ASP F OD2   1 
ATOM   7328 N N     . LEU B 2 176 ? 194.222 201.058 186.908 1.00 37.50  ? 180 LEU F N     1 
ATOM   7329 C CA    . LEU B 2 176 ? 194.153 202.107 187.908 1.00 37.50  ? 180 LEU F CA    1 
ATOM   7330 C C     . LEU B 2 176 ? 192.700 202.520 188.072 1.00 37.50  ? 180 LEU F C     1 
ATOM   7331 O O     . LEU B 2 176 ? 192.021 202.802 187.085 1.00 37.50  ? 180 LEU F O     1 
ATOM   7332 C CB    . LEU B 2 176 ? 195.015 203.287 187.478 1.00 37.50  ? 180 LEU F CB    1 
ATOM   7333 C CG    . LEU B 2 176 ? 194.888 204.647 188.137 1.00 37.50  ? 180 LEU F CG    1 
ATOM   7334 C CD1   . LEU B 2 176 ? 195.032 204.551 189.622 1.00 37.50  ? 180 LEU F CD1   1 
ATOM   7335 C CD2   . LEU B 2 176 ? 195.977 205.499 187.578 1.00 37.50  ? 180 LEU F CD2   1 
ATOM   7336 N N     . ALA B 2 177 ? 192.222 202.550 189.308 1.00 39.11  ? 181 ALA F N     1 
ATOM   7337 C CA    . ALA B 2 177 ? 190.806 202.778 189.525 1.00 39.11  ? 181 ALA F CA    1 
ATOM   7338 C C     . ALA B 2 177 ? 190.587 203.295 190.943 1.00 39.11  ? 181 ALA F C     1 
ATOM   7339 O O     . ALA B 2 177 ? 191.513 203.808 191.581 1.00 39.11  ? 181 ALA F O     1 
ATOM   7340 C CB    . ALA B 2 177 ? 190.015 201.498 189.239 1.00 39.11  ? 181 ALA F CB    1 
ATOM   7341 N N     . GLY B 2 178 ? 189.348 203.186 191.418 1.00 38.67  ? 182 GLY F N     1 
ATOM   7342 C CA    . GLY B 2 178 ? 188.996 203.726 192.716 1.00 38.67  ? 182 GLY F CA    1 
ATOM   7343 C C     . GLY B 2 178 ? 189.724 203.088 193.877 1.00 38.67  ? 182 GLY F C     1 
ATOM   7344 O O     . GLY B 2 178 ? 189.996 203.754 194.875 1.00 38.67  ? 182 GLY F O     1 
ATOM   7345 N N     . ARG B 2 179 ? 190.051 201.804 193.777 1.00 40.23  ? 183 ARG F N     1 
ATOM   7346 C CA    . ARG B 2 179 ? 190.763 201.155 194.870 1.00 40.23  ? 183 ARG F CA    1 
ATOM   7347 C C     . ARG B 2 179 ? 192.170 201.708 195.014 1.00 40.23  ? 183 ARG F C     1 
ATOM   7348 O O     . ARG B 2 179 ? 192.646 201.943 196.130 1.00 40.23  ? 183 ARG F O     1 
ATOM   7349 C CB    . ARG B 2 179 ? 190.800 199.654 194.646 1.00 40.23  ? 183 ARG F CB    1 
ATOM   7350 C CG    . ARG B 2 179 ? 191.227 198.869 195.846 1.00 40.23  ? 183 ARG F CG    1 
ATOM   7351 C CD    . ARG B 2 179 ? 190.043 198.456 196.676 1.00 40.23  ? 183 ARG F CD    1 
ATOM   7352 N NE    . ARG B 2 179 ? 189.022 197.794 195.880 1.00 40.23  ? 183 ARG F NE    1 
ATOM   7353 C CZ    . ARG B 2 179 ? 189.120 196.550 195.438 1.00 40.23  ? 183 ARG F CZ    1 
ATOM   7354 N NH1   . ARG B 2 179 ? 190.196 195.836 195.713 1.00 40.23  ? 183 ARG F NH1   1 
ATOM   7355 N NH2   . ARG B 2 179 ? 188.144 196.022 194.722 1.00 40.23  ? 183 ARG F NH2   1 
ATOM   7356 N N     . ASP B 2 180 ? 192.846 201.943 193.896 1.00 39.25  ? 184 ASP F N     1 
ATOM   7357 C CA    . ASP B 2 180 ? 194.159 202.564 193.954 1.00 39.25  ? 184 ASP F CA    1 
ATOM   7358 C C     . ASP B 2 180 ? 194.070 204.014 194.374 1.00 39.25  ? 184 ASP F C     1 
ATOM   7359 O O     . ASP B 2 180 ? 194.982 204.519 195.029 1.00 39.25  ? 184 ASP F O     1 
ATOM   7360 C CB    . ASP B 2 180 ? 194.849 202.452 192.609 1.00 39.25  ? 184 ASP F CB    1 
ATOM   7361 C CG    . ASP B 2 180 ? 194.914 201.040 192.121 1.00 39.25  ? 184 ASP F CG    1 
ATOM   7362 O OD1   . ASP B 2 180 ? 193.862 200.502 191.722 1.00 39.25  ? 184 ASP F OD1   1 
ATOM   7363 O OD2   . ASP B 2 180 ? 196.014 200.457 192.148 1.00 39.25  ? 184 ASP F OD2   1 
ATOM   7364 N N     . LEU B 2 181 ? 192.983 204.698 194.031 1.00 35.56  ? 185 LEU F N     1 
ATOM   7365 C CA    . LEU B 2 181 ? 192.819 206.057 194.527 1.00 35.56  ? 185 LEU F CA    1 
ATOM   7366 C C     . LEU B 2 181 ? 192.618 206.073 196.034 1.00 35.56  ? 185 LEU F C     1 
ATOM   7367 O O     . LEU B 2 181 ? 193.123 206.963 196.721 1.00 35.56  ? 185 LEU F O     1 
ATOM   7368 C CB    . LEU B 2 181 ? 191.655 206.741 193.828 1.00 35.56  ? 185 LEU F CB    1 
ATOM   7369 C CG    . LEU B 2 181 ? 191.891 207.123 192.379 1.00 35.56  ? 185 LEU F CG    1 
ATOM   7370 C CD1   . LEU B 2 181 ? 190.767 207.979 191.910 1.00 35.56  ? 185 LEU F CD1   1 
ATOM   7371 C CD2   . LEU B 2 181 ? 193.173 207.855 192.260 1.00 35.56  ? 185 LEU F CD2   1 
ATOM   7372 N N     . THR B 2 182 ? 191.894 205.095 196.570 1.00 35.46  ? 186 THR F N     1 
ATOM   7373 C CA    . THR B 2 182 ? 191.739 205.004 198.016 1.00 35.46  ? 186 THR F CA    1 
ATOM   7374 C C     . THR B 2 182 ? 193.069 204.728 198.694 1.00 35.46  ? 186 THR F C     1 
ATOM   7375 O O     . THR B 2 182 ? 193.381 205.319 199.731 1.00 35.46  ? 186 THR F O     1 
ATOM   7376 C CB    . THR B 2 182 ? 190.746 203.909 198.375 1.00 35.46  ? 186 THR F CB    1 
ATOM   7377 O OG1   . THR B 2 182 ? 189.487 204.180 197.764 1.00 35.46  ? 186 THR F OG1   1 
ATOM   7378 C CG2   . THR B 2 182 ? 190.555 203.849 199.852 1.00 35.46  ? 186 THR F CG2   1 
ATOM   7379 N N     . ASP B 2 183 ? 193.860 203.817 198.140 1.00 36.33  ? 187 ASP F N     1 
ATOM   7380 C CA    . ASP B 2 183 ? 195.157 203.539 198.742 1.00 36.33  ? 187 ASP F CA    1 
ATOM   7381 C C     . ASP B 2 183 ? 196.061 204.757 198.687 1.00 36.33  ? 187 ASP F C     1 
ATOM   7382 O O     . ASP B 2 183 ? 196.785 205.048 199.646 1.00 36.33  ? 187 ASP F O     1 
ATOM   7383 C CB    . ASP B 2 183 ? 195.810 202.354 198.055 1.00 36.33  ? 187 ASP F CB    1 
ATOM   7384 C CG    . ASP B 2 183 ? 194.981 201.109 198.159 1.00 36.33  ? 187 ASP F CG    1 
ATOM   7385 O OD1   . ASP B 2 183 ? 193.953 201.146 198.857 1.00 36.33  ? 187 ASP F OD1   1 
ATOM   7386 O OD2   . ASP B 2 183 ? 195.349 200.092 197.540 1.00 36.33  ? 187 ASP F OD2   1 
ATOM   7387 N N     . TYR B 2 184 ? 196.030 205.492 197.584 1.00 33.03  ? 188 TYR F N     1 
ATOM   7388 C CA    . TYR B 2 184 ? 196.834 206.700 197.517 1.00 33.03  ? 188 TYR F CA    1 
ATOM   7389 C C     . TYR B 2 184 ? 196.342 207.739 198.506 1.00 33.03  ? 188 TYR F C     1 
ATOM   7390 O O     . TYR B 2 184 ? 197.143 208.467 199.088 1.00 33.03  ? 188 TYR F O     1 
ATOM   7391 C CB    . TYR B 2 184 ? 196.828 207.268 196.108 1.00 33.03  ? 188 TYR F CB    1 
ATOM   7392 C CG    . TYR B 2 184 ? 197.736 208.446 195.951 1.00 33.03  ? 188 TYR F CG    1 
ATOM   7393 C CD1   . TYR B 2 184 ? 199.095 208.317 196.111 1.00 33.03  ? 188 TYR F CD1   1 
ATOM   7394 C CD2   . TYR B 2 184 ? 197.234 209.688 195.648 1.00 33.03  ? 188 TYR F CD2   1 
ATOM   7395 C CE1   . TYR B 2 184 ? 199.923 209.386 195.969 1.00 33.03  ? 188 TYR F CE1   1 
ATOM   7396 C CE2   . TYR B 2 184 ? 198.056 210.762 195.506 1.00 33.03  ? 188 TYR F CE2   1 
ATOM   7397 C CZ    . TYR B 2 184 ? 199.398 210.608 195.668 1.00 33.03  ? 188 TYR F CZ    1 
ATOM   7398 O OH    . TYR B 2 184 ? 200.223 211.688 195.523 1.00 33.03  ? 188 TYR F OH    1 
ATOM   7399 N N     . LEU B 2 185 ? 195.036 207.822 198.725 1.00 33.68  ? 189 LEU F N     1 
ATOM   7400 C CA    . LEU B 2 185 ? 194.537 208.811 199.668 1.00 33.68  ? 189 LEU F CA    1 
ATOM   7401 C C     . LEU B 2 185 ? 194.915 208.453 201.095 1.00 33.68  ? 189 LEU F C     1 
ATOM   7402 O O     . LEU B 2 185 ? 195.224 209.336 201.891 1.00 33.68  ? 189 LEU F O     1 
ATOM   7403 C CB    . LEU B 2 185 ? 193.031 208.958 199.536 1.00 33.68  ? 189 LEU F CB    1 
ATOM   7404 C CG    . LEU B 2 185 ? 192.468 210.052 200.423 1.00 33.68  ? 189 LEU F CG    1 
ATOM   7405 C CD1   . LEU B 2 185 ? 193.101 211.355 200.071 1.00 33.68  ? 189 LEU F CD1   1 
ATOM   7406 C CD2   . LEU B 2 185 ? 190.988 210.129 200.268 1.00 33.68  ? 189 LEU F CD2   1 
ATOM   7407 N N     . MET B 2 186 ? 194.883 207.171 201.449 1.00 34.83  ? 190 MET F N     1 
ATOM   7408 C CA    . MET B 2 186 ? 195.412 206.757 202.743 1.00 34.83  ? 190 MET F CA    1 
ATOM   7409 C C     . MET B 2 186 ? 196.857 207.205 202.890 1.00 34.83  ? 190 MET F C     1 
ATOM   7410 O O     . MET B 2 186 ? 197.215 207.954 203.812 1.00 34.83  ? 190 MET F O     1 
ATOM   7411 C CB    . MET B 2 186 ? 195.302 205.241 202.893 1.00 34.83  ? 190 MET F CB    1 
ATOM   7412 C CG    . MET B 2 186 ? 193.888 204.749 203.018 1.00 34.83  ? 190 MET F CG    1 
ATOM   7413 S SD    . MET B 2 186 ? 193.665 202.973 202.861 1.00 34.83  ? 190 MET F SD    1 
ATOM   7414 C CE    . MET B 2 186 ? 194.327 202.396 204.396 1.00 34.83  ? 190 MET F CE    1 
ATOM   7415 N N     . LYS B 2 187 ? 197.697 206.769 201.955 1.00 34.14  ? 191 LYS F N     1 
ATOM   7416 C CA    . LYS B 2 187 ? 199.118 207.078 202.021 1.00 34.14  ? 191 LYS F CA    1 
ATOM   7417 C C     . LYS B 2 187 ? 199.383 208.575 202.012 1.00 34.14  ? 191 LYS F C     1 
ATOM   7418 O O     . LYS B 2 187 ? 200.414 209.019 202.516 1.00 34.14  ? 191 LYS F O     1 
ATOM   7419 C CB    . LYS B 2 187 ? 199.832 206.401 200.858 1.00 34.14  ? 191 LYS F CB    1 
ATOM   7420 C CG    . LYS B 2 187 ? 201.314 206.593 200.826 1.00 34.14  ? 191 LYS F CG    1 
ATOM   7421 C CD    . LYS B 2 187 ? 201.737 207.108 199.480 1.00 34.14  ? 191 LYS F CD    1 
ATOM   7422 C CE    . LYS B 2 187 ? 203.241 207.168 199.359 1.00 34.14  ? 191 LYS F CE    1 
ATOM   7423 N NZ    . LYS B 2 187 ? 203.655 207.835 198.096 1.00 34.14  ? 191 LYS F NZ    1 
ATOM   7424 N N     . ILE B 2 188 ? 198.485 209.373 201.448 1.00 34.23  ? 192 ILE F N     1 
ATOM   7425 C CA    . ILE B 2 188 ? 198.741 210.803 201.361 1.00 34.23  ? 192 ILE F CA    1 
ATOM   7426 C C     . ILE B 2 188 ? 198.157 211.552 202.550 1.00 34.23  ? 192 ILE F C     1 
ATOM   7427 O O     . ILE B 2 188 ? 198.637 212.640 202.882 1.00 34.23  ? 192 ILE F O     1 
ATOM   7428 C CB    . ILE B 2 188 ? 198.206 211.369 200.032 1.00 34.23  ? 192 ILE F CB    1 
ATOM   7429 C CG1   . ILE B 2 188 ? 198.980 212.601 199.637 1.00 34.23  ? 192 ILE F CG1   1 
ATOM   7430 C CG2   . ILE B 2 188 ? 196.780 211.804 200.143 1.00 34.23  ? 192 ILE F CG2   1 
ATOM   7431 C CD1   . ILE B 2 188 ? 200.380 212.298 199.254 1.00 34.23  ? 192 ILE F CD1   1 
ATOM   7432 N N     . LEU B 2 189 ? 197.134 210.999 203.201 1.00 34.97  ? 193 LEU F N     1 
ATOM   7433 C CA    . LEU B 2 189 ? 196.641 211.558 204.447 1.00 34.97  ? 193 LEU F CA    1 
ATOM   7434 C C     . LEU B 2 189 ? 197.633 211.350 205.567 1.00 34.97  ? 193 LEU F C     1 
ATOM   7435 O O     . LEU B 2 189 ? 197.708 212.170 206.483 1.00 34.97  ? 193 LEU F O     1 
ATOM   7436 C CB    . LEU B 2 189 ? 195.317 210.912 204.829 1.00 34.97  ? 193 LEU F CB    1 
ATOM   7437 C CG    . LEU B 2 189 ? 194.057 211.477 204.206 1.00 34.97  ? 193 LEU F CG    1 
ATOM   7438 C CD1   . LEU B 2 189 ? 192.872 210.751 204.751 1.00 34.97  ? 193 LEU F CD1   1 
ATOM   7439 C CD2   . LEU B 2 189 ? 193.982 212.925 204.540 1.00 34.97  ? 193 LEU F CD2   1 
ATOM   7440 N N     . THR B 2 190 ? 198.404 210.265 205.512 1.00 37.19  ? 194 THR F N     1 
ATOM   7441 C CA    . THR B 2 190 ? 199.348 210.002 206.590 1.00 37.19  ? 194 THR F CA    1 
ATOM   7442 C C     . THR B 2 190 ? 200.325 211.149 206.808 1.00 37.19  ? 194 THR F C     1 
ATOM   7443 O O     . THR B 2 190 ? 200.918 211.237 207.882 1.00 37.19  ? 194 THR F O     1 
ATOM   7444 C CB    . THR B 2 190 ? 200.126 208.722 206.321 1.00 37.19  ? 194 THR F CB    1 
ATOM   7445 O OG1   . THR B 2 190 ? 200.667 208.245 207.548 1.00 37.19  ? 194 THR F OG1   1 
ATOM   7446 C CG2   . THR B 2 190 ? 201.283 209.009 205.431 1.00 37.19  ? 194 THR F CG2   1 
ATOM   7447 N N     . GLU B 2 191 ? 200.504 212.033 205.835 1.00 39.34  ? 195 GLU F N     1 
ATOM   7448 C CA    . GLU B 2 191 ? 201.448 213.130 205.981 1.00 39.34  ? 195 GLU F CA    1 
ATOM   7449 C C     . GLU B 2 191 ? 200.847 214.334 206.671 1.00 39.34  ? 195 GLU F C     1 
ATOM   7450 O O     . GLU B 2 191 ? 201.555 215.314 206.901 1.00 39.34  ? 195 GLU F O     1 
ATOM   7451 C CB    . GLU B 2 191 ? 201.991 213.558 204.621 1.00 39.34  ? 195 GLU F CB    1 
ATOM   7452 C CG    . GLU B 2 191 ? 201.123 214.558 203.905 1.00 39.34  ? 195 GLU F CG    1 
ATOM   7453 C CD    . GLU B 2 191 ? 201.444 214.660 202.433 1.00 39.34  ? 195 GLU F CD    1 
ATOM   7454 O OE1   . GLU B 2 191 ? 202.269 213.866 201.948 1.00 39.34  ? 195 GLU F OE1   1 
ATOM   7455 O OE2   . GLU B 2 191 ? 200.863 215.528 201.756 1.00 39.34  ? 195 GLU F OE2   1 
ATOM   7456 N N     . ARG B 2 192 ? 199.568 214.293 206.996 1.00 39.67  ? 196 ARG F N     1 
ATOM   7457 C CA    . ARG B 2 192 ? 198.953 215.341 207.785 1.00 39.67  ? 196 ARG F CA    1 
ATOM   7458 C C     . ARG B 2 192 ? 198.726 214.922 209.224 1.00 39.67  ? 196 ARG F C     1 
ATOM   7459 O O     . ARG B 2 192 ? 198.356 215.760 210.047 1.00 39.67  ? 196 ARG F O     1 
ATOM   7460 C CB    . ARG B 2 192 ? 197.629 215.762 207.155 1.00 39.67  ? 196 ARG F CB    1 
ATOM   7461 C CG    . ARG B 2 192 ? 197.213 217.159 207.489 1.00 39.67  ? 196 ARG F CG    1 
ATOM   7462 C CD    . ARG B 2 192 ? 196.045 217.571 206.642 1.00 39.67  ? 196 ARG F CD    1 
ATOM   7463 N NE    . ARG B 2 192 ? 196.452 218.468 205.575 1.00 39.67  ? 196 ARG F NE    1 
ATOM   7464 C CZ    . ARG B 2 192 ? 196.231 219.773 205.589 1.00 39.67  ? 196 ARG F CZ    1 
ATOM   7465 N NH1   . ARG B 2 192 ? 195.605 220.322 206.613 1.00 39.67  ? 196 ARG F NH1   1 
ATOM   7466 N NH2   . ARG B 2 192 ? 196.633 220.527 204.581 1.00 39.67  ? 196 ARG F NH2   1 
ATOM   7467 N N     . GLY B 2 193 ? 198.938 213.655 209.546 1.00 39.58  ? 197 GLY F N     1 
ATOM   7468 C CA    . GLY B 2 193 ? 198.898 213.218 210.918 1.00 39.58  ? 197 GLY F CA    1 
ATOM   7469 C C     . GLY B 2 193 ? 197.933 212.089 211.177 1.00 39.58  ? 197 GLY F C     1 
ATOM   7470 O O     . GLY B 2 193 ? 198.016 211.427 212.211 1.00 39.58  ? 197 GLY F O     1 
ATOM   7471 N N     . TYR B 2 194 ? 197.020 211.843 210.255 1.00 38.81  ? 198 TYR F N     1 
ATOM   7472 C CA    . TYR B 2 194 ? 196.026 210.801 210.429 1.00 38.81  ? 198 TYR F CA    1 
ATOM   7473 C C     . TYR B 2 194 ? 196.544 209.512 209.823 1.00 38.81  ? 198 TYR F C     1 
ATOM   7474 O O     . TYR B 2 194 ? 197.196 209.529 208.780 1.00 38.81  ? 198 TYR F O     1 
ATOM   7475 C CB    . TYR B 2 194 ? 194.707 211.198 209.777 1.00 38.81  ? 198 TYR F CB    1 
ATOM   7476 C CG    . TYR B 2 194 ? 194.419 212.667 209.868 1.00 38.81  ? 198 TYR F CG    1 
ATOM   7477 C CD1   . TYR B 2 194 ? 194.039 213.238 211.057 1.00 38.81  ? 198 TYR F CD1   1 
ATOM   7478 C CD2   . TYR B 2 194 ? 194.532 213.480 208.765 1.00 38.81  ? 198 TYR F CD2   1 
ATOM   7479 C CE1   . TYR B 2 194 ? 193.780 214.572 211.146 1.00 38.81  ? 198 TYR F CE1   1 
ATOM   7480 C CE2   . TYR B 2 194 ? 194.274 214.814 208.845 1.00 38.81  ? 198 TYR F CE2   1 
ATOM   7481 C CZ    . TYR B 2 194 ? 193.902 215.357 210.040 1.00 38.81  ? 198 TYR F CZ    1 
ATOM   7482 O OH    . TYR B 2 194 ? 193.640 216.699 210.132 1.00 38.81  ? 198 TYR F OH    1 
ATOM   7483 N N     . SER B 2 195 ? 196.270 208.395 210.482 1.00 38.45  ? 199 SER F N     1 
ATOM   7484 C CA    . SER B 2 195 ? 196.704 207.094 209.995 1.00 38.45  ? 199 SER F CA    1 
ATOM   7485 C C     . SER B 2 195 ? 195.517 206.153 209.991 1.00 38.45  ? 199 SER F C     1 
ATOM   7486 O O     . SER B 2 195 ? 194.868 205.965 211.023 1.00 38.45  ? 199 SER F O     1 
ATOM   7487 C CB    . SER B 2 195 ? 197.823 206.517 210.855 1.00 38.45  ? 199 SER F CB    1 
ATOM   7488 O OG    . SER B 2 195 ? 197.280 205.756 211.913 1.00 38.45  ? 199 SER F OG    1 
ATOM   7489 N N     . PHE B 2 196 ? 195.236 205.570 208.835 1.00 38.30  ? 200 PHE F N     1 
ATOM   7490 C CA    . PHE B 2 196 ? 194.222 204.542 208.681 1.00 38.30  ? 200 PHE F CA    1 
ATOM   7491 C C     . PHE B 2 196 ? 194.917 203.324 208.102 1.00 38.30  ? 200 PHE F C     1 
ATOM   7492 O O     . PHE B 2 196 ? 195.509 203.409 207.024 1.00 38.30  ? 200 PHE F O     1 
ATOM   7493 C CB    . PHE B 2 196 ? 193.103 205.014 207.760 1.00 38.30  ? 200 PHE F CB    1 
ATOM   7494 C CG    . PHE B 2 196 ? 192.608 206.390 208.065 1.00 38.30  ? 200 PHE F CG    1 
ATOM   7495 C CD1   . PHE B 2 196 ? 191.596 206.589 208.973 1.00 38.30  ? 200 PHE F CD1   1 
ATOM   7496 C CD2   . PHE B 2 196 ? 193.145 207.485 207.435 1.00 38.30  ? 200 PHE F CD2   1 
ATOM   7497 C CE1   . PHE B 2 196 ? 191.141 207.843 209.246 1.00 38.30  ? 200 PHE F CE1   1 
ATOM   7498 C CE2   . PHE B 2 196 ? 192.686 208.744 207.713 1.00 38.30  ? 200 PHE F CE2   1 
ATOM   7499 C CZ    . PHE B 2 196 ? 191.688 208.919 208.618 1.00 38.30  ? 200 PHE F CZ    1 
ATOM   7500 N N     . VAL B 2 197 ? 194.900 202.209 208.829 1.00 37.75  ? 201 VAL F N     1 
ATOM   7501 C CA    . VAL B 2 197 ? 195.672 201.036 208.451 1.00 37.75  ? 201 VAL F CA    1 
ATOM   7502 C C     . VAL B 2 197 ? 194.799 199.807 208.236 1.00 37.75  ? 201 VAL F C     1 
ATOM   7503 O O     . VAL B 2 197 ? 195.069 199.008 207.337 1.00 37.75  ? 201 VAL F O     1 
ATOM   7504 C CB    . VAL B 2 197 ? 196.782 200.747 209.476 1.00 37.75  ? 201 VAL F CB    1 
ATOM   7505 C CG1   . VAL B 2 197 ? 197.841 201.810 209.373 1.00 37.75  ? 201 VAL F CG1   1 
ATOM   7506 C CG2   . VAL B 2 197 ? 196.227 200.728 210.871 1.00 37.75  ? 201 VAL F CG2   1 
ATOM   7507 N N     . THR B 2 198 ? 193.762 199.624 209.039 1.00 37.74  ? 202 THR F N     1 
ATOM   7508 C CA    . THR B 2 198 ? 192.983 198.401 208.953 1.00 37.74  ? 202 THR F CA    1 
ATOM   7509 C C     . THR B 2 198 ? 192.048 198.408 207.745 1.00 37.74  ? 202 THR F C     1 
ATOM   7510 O O     . THR B 2 198 ? 191.737 199.450 207.159 1.00 37.74  ? 202 THR F O     1 
ATOM   7511 C CB    . THR B 2 198 ? 192.181 198.202 210.230 1.00 37.74  ? 202 THR F CB    1 
ATOM   7512 O OG1   . THR B 2 198 ? 191.164 199.198 210.310 1.00 37.74  ? 202 THR F OG1   1 
ATOM   7513 C CG2   . THR B 2 198 ? 193.077 198.351 211.421 1.00 37.74  ? 202 THR F CG2   1 
ATOM   7514 N N     . THR B 2 199 ? 191.593 197.210 207.376 1.00 37.93  ? 203 THR F N     1 
ATOM   7515 C CA    . THR B 2 199 ? 190.621 197.094 206.298 1.00 37.93  ? 203 THR F CA    1 
ATOM   7516 C C     . THR B 2 199 ? 189.312 197.771 206.640 1.00 37.93  ? 203 THR F C     1 
ATOM   7517 O O     . THR B 2 199 ? 188.548 198.105 205.736 1.00 37.93  ? 203 THR F O     1 
ATOM   7518 C CB    . THR B 2 199 ? 190.342 195.636 205.967 1.00 37.93  ? 203 THR F CB    1 
ATOM   7519 O OG1   . THR B 2 199 ? 189.562 195.059 207.011 1.00 37.93  ? 203 THR F OG1   1 
ATOM   7520 C CG2   . THR B 2 199 ? 191.622 194.873 205.840 1.00 37.93  ? 203 THR F CG2   1 
ATOM   7521 N N     . ALA B 2 200 ? 189.026 197.961 207.919 1.00 37.79  ? 204 ALA F N     1 
ATOM   7522 C CA    . ALA B 2 200 ? 187.841 198.685 208.334 1.00 37.79  ? 204 ALA F CA    1 
ATOM   7523 C C     . ALA B 2 200 ? 188.035 200.186 208.293 1.00 37.79  ? 204 ALA F C     1 
ATOM   7524 O O     . ALA B 2 200 ? 187.050 200.920 208.323 1.00 37.79  ? 204 ALA F O     1 
ATOM   7525 C CB    . ALA B 2 200 ? 187.436 198.262 209.738 1.00 37.79  ? 204 ALA F CB    1 
ATOM   7526 N N     . GLU B 2 201 ? 189.272 200.661 208.264 1.00 38.87  ? 205 GLU F N     1 
ATOM   7527 C CA    . GLU B 2 201 ? 189.516 202.077 208.051 1.00 38.87  ? 205 GLU F CA    1 
ATOM   7528 C C     . GLU B 2 201 ? 189.660 202.415 206.581 1.00 38.87  ? 205 GLU F C     1 
ATOM   7529 O O     . GLU B 2 201 ? 189.493 203.580 206.203 1.00 38.87  ? 205 GLU F O     1 
ATOM   7530 C CB    . GLU B 2 201 ? 190.756 202.519 208.814 1.00 38.87  ? 205 GLU F CB    1 
ATOM   7531 C CG    . GLU B 2 201 ? 190.516 202.678 210.293 1.00 38.87  ? 205 GLU F CG    1 
ATOM   7532 C CD    . GLU B 2 201 ? 191.778 202.550 211.118 1.00 38.87  ? 205 GLU F CD    1 
ATOM   7533 O OE1   . GLU B 2 201 ? 192.622 201.688 210.798 1.00 38.87  ? 205 GLU F OE1   1 
ATOM   7534 O OE2   . GLU B 2 201 ? 191.930 203.313 212.093 1.00 38.87  ? 205 GLU F OE2   1 
ATOM   7535 N N     . ARG B 2 202 ? 189.960 201.425 205.744 1.00 38.28  ? 206 ARG F N     1 
ATOM   7536 C CA    . ARG B 2 202 ? 189.895 201.650 204.306 1.00 38.28  ? 206 ARG F CA    1 
ATOM   7537 C C     . ARG B 2 202 ? 188.515 202.135 203.885 1.00 38.28  ? 206 ARG F C     1 
ATOM   7538 O O     . ARG B 2 202 ? 188.394 202.976 202.992 1.00 38.28  ? 206 ARG F O     1 
ATOM   7539 C CB    . ARG B 2 202 ? 190.257 200.375 203.560 1.00 38.28  ? 206 ARG F CB    1 
ATOM   7540 C CG    . ARG B 2 202 ? 190.674 200.599 202.127 1.00 38.28  ? 206 ARG F CG    1 
ATOM   7541 C CD    . ARG B 2 202 ? 190.913 199.280 201.428 1.00 38.28  ? 206 ARG F CD    1 
ATOM   7542 N NE    . ARG B 2 202 ? 191.671 198.372 202.273 1.00 38.28  ? 206 ARG F NE    1 
ATOM   7543 C CZ    . ARG B 2 202 ? 192.983 198.444 202.453 1.00 38.28  ? 206 ARG F CZ    1 
ATOM   7544 N NH1   . ARG B 2 202 ? 193.686 199.379 201.835 1.00 38.28  ? 206 ARG F NH1   1 
ATOM   7545 N NH2   . ARG B 2 202 ? 193.591 197.580 203.252 1.00 38.28  ? 206 ARG F NH2   1 
ATOM   7546 N N     . GLU B 2 203 ? 187.460 201.631 204.524 1.00 38.21  ? 207 GLU F N     1 
ATOM   7547 C CA    . GLU B 2 203 ? 186.111 202.063 204.180 1.00 38.21  ? 207 GLU F CA    1 
ATOM   7548 C C     . GLU B 2 203 ? 185.862 203.506 204.590 1.00 38.21  ? 207 GLU F C     1 
ATOM   7549 O O     . GLU B 2 203 ? 185.203 204.261 203.867 1.00 38.21  ? 207 GLU F O     1 
ATOM   7550 C CB    . GLU B 2 203 ? 185.090 201.148 204.836 1.00 38.21  ? 207 GLU F CB    1 
ATOM   7551 C CG    . GLU B 2 203 ? 185.357 199.696 204.608 1.00 38.21  ? 207 GLU F CG    1 
ATOM   7552 C CD    . GLU B 2 203 ? 185.476 199.357 203.145 1.00 38.21  ? 207 GLU F CD    1 
ATOM   7553 O OE1   . GLU B 2 203 ? 184.667 199.866 202.346 1.00 38.21  ? 207 GLU F OE1   1 
ATOM   7554 O OE2   . GLU B 2 203 ? 186.381 198.579 202.784 1.00 38.21  ? 207 GLU F OE2   1 
ATOM   7555 N N     . ILE B 2 204 ? 186.375 203.912 205.744 1.00 36.52  ? 208 ILE F N     1 
ATOM   7556 C CA    . ILE B 2 204 ? 186.246 205.304 206.151 1.00 36.52  ? 208 ILE F CA    1 
ATOM   7557 C C     . ILE B 2 204 ? 186.967 206.208 205.168 1.00 36.52  ? 208 ILE F C     1 
ATOM   7558 O O     . ILE B 2 204 ? 186.486 207.294 204.829 1.00 36.52  ? 208 ILE F O     1 
ATOM   7559 C CB    . ILE B 2 204 ? 186.775 205.478 207.584 1.00 36.52  ? 208 ILE F CB    1 
ATOM   7560 C CG1   . ILE B 2 204 ? 185.955 204.626 208.544 1.00 36.52  ? 208 ILE F CG1   1 
ATOM   7561 C CG2   . ILE B 2 204 ? 186.749 206.920 207.996 1.00 36.52  ? 208 ILE F CG2   1 
ATOM   7562 C CD1   . ILE B 2 204 ? 186.611 204.428 209.865 1.00 36.52  ? 208 ILE F CD1   1 
ATOM   7563 N N     . VAL B 2 205 ? 188.129 205.773 204.687 1.00 35.04  ? 209 VAL F N     1 
ATOM   7564 C CA    . VAL B 2 205 ? 188.871 206.591 203.734 1.00 35.04  ? 209 VAL F CA    1 
ATOM   7565 C C     . VAL B 2 205 ? 188.139 206.667 202.404 1.00 35.04  ? 209 VAL F C     1 
ATOM   7566 O O     . VAL B 2 205 ? 188.138 207.706 201.739 1.00 35.04  ? 209 VAL F O     1 
ATOM   7567 C CB    . VAL B 2 205 ? 190.294 206.051 203.556 1.00 35.04  ? 209 VAL F CB    1 
ATOM   7568 C CG1   . VAL B 2 205 ? 191.027 206.883 202.548 1.00 35.04  ? 209 VAL F CG1   1 
ATOM   7569 C CG2   . VAL B 2 205 ? 191.010 206.085 204.862 1.00 35.04  ? 209 VAL F CG2   1 
ATOM   7570 N N     . ARG B 2 206 ? 187.512 205.571 201.989 1.00 37.10  ? 210 ARG F N     1 
ATOM   7571 C CA    . ARG B 2 206 ? 186.730 205.603 200.763 1.00 37.10  ? 210 ARG F CA    1 
ATOM   7572 C C     . ARG B 2 206 ? 185.572 206.575 200.887 1.00 37.10  ? 210 ARG F C     1 
ATOM   7573 O O     . ARG B 2 206 ? 185.237 207.289 199.934 1.00 37.10  ? 210 ARG F O     1 
ATOM   7574 C CB    . ARG B 2 206 ? 186.219 204.211 200.435 1.00 37.10  ? 210 ARG F CB    1 
ATOM   7575 C CG    . ARG B 2 206 ? 185.391 204.167 199.198 1.00 37.10  ? 210 ARG F CG    1 
ATOM   7576 C CD    . ARG B 2 206 ? 184.803 202.803 198.984 1.00 37.10  ? 210 ARG F CD    1 
ATOM   7577 N NE    . ARG B 2 206 ? 184.060 202.351 200.146 1.00 37.10  ? 210 ARG F NE    1 
ATOM   7578 C CZ    . ARG B 2 206 ? 182.857 202.794 200.472 1.00 37.10  ? 210 ARG F CZ    1 
ATOM   7579 N NH1   . ARG B 2 206 ? 182.266 203.705 199.724 1.00 37.10  ? 210 ARG F NH1   1 
ATOM   7580 N NH2   . ARG B 2 206 ? 182.248 202.330 201.549 1.00 37.10  ? 210 ARG F NH2   1 
ATOM   7581 N N     . ASP B 2 207 ? 184.953 206.624 202.059 1.00 38.29  ? 211 ASP F N     1 
ATOM   7582 C CA    . ASP B 2 207 ? 183.878 207.581 202.268 1.00 38.29  ? 211 ASP F CA    1 
ATOM   7583 C C     . ASP B 2 207 ? 184.387 209.013 202.221 1.00 38.29  ? 211 ASP F C     1 
ATOM   7584 O O     . ASP B 2 207 ? 183.742 209.884 201.629 1.00 38.29  ? 211 ASP F O     1 
ATOM   7585 C CB    . ASP B 2 207 ? 183.197 207.305 203.593 1.00 38.29  ? 211 ASP F CB    1 
ATOM   7586 C CG    . ASP B 2 207 ? 181.913 208.043 203.726 1.00 38.29  ? 211 ASP F CG    1 
ATOM   7587 O OD1   . ASP B 2 207 ? 181.388 208.468 202.681 1.00 38.29  ? 211 ASP F OD1   1 
ATOM   7588 O OD2   . ASP B 2 207 ? 181.431 208.211 204.863 1.00 38.29  ? 211 ASP F OD2   1 
ATOM   7589 N N     . ILE B 2 208 ? 185.533 209.281 202.844 1.00 36.84  ? 212 ILE F N     1 
ATOM   7590 C CA    . ILE B 2 208 ? 186.136 210.608 202.750 1.00 36.84  ? 212 ILE F CA    1 
ATOM   7591 C C     . ILE B 2 208 ? 186.356 210.985 201.297 1.00 36.84  ? 212 ILE F C     1 
ATOM   7592 O O     . ILE B 2 208 ? 186.079 212.113 200.879 1.00 36.84  ? 212 ILE F O     1 
ATOM   7593 C CB    . ILE B 2 208 ? 187.461 210.663 203.525 1.00 36.84  ? 212 ILE F CB    1 
ATOM   7594 C CG1   . ILE B 2 208 ? 187.237 210.432 205.005 1.00 36.84  ? 212 ILE F CG1   1 
ATOM   7595 C CG2   . ILE B 2 208 ? 188.137 211.989 203.320 1.00 36.84  ? 212 ILE F CG2   1 
ATOM   7596 C CD1   . ILE B 2 208 ? 188.508 210.367 205.775 1.00 36.84  ? 212 ILE F CD1   1 
ATOM   7597 N N     . LYS B 2 209 ? 186.886 210.051 200.512 1.00 37.12  ? 213 LYS F N     1 
ATOM   7598 C CA    . LYS B 2 209 ? 187.174 210.329 199.112 1.00 37.12  ? 213 LYS F CA    1 
ATOM   7599 C C     . LYS B 2 209 ? 185.912 210.706 198.362 1.00 37.12  ? 213 LYS F C     1 
ATOM   7600 O O     . LYS B 2 209 ? 185.834 211.781 197.756 1.00 37.12  ? 213 LYS F O     1 
ATOM   7601 C CB    . LYS B 2 209 ? 187.832 209.117 198.468 1.00 37.12  ? 213 LYS F CB    1 
ATOM   7602 C CG    . LYS B 2 209 ? 187.903 209.186 196.979 1.00 37.12  ? 213 LYS F CG    1 
ATOM   7603 C CD    . LYS B 2 209 ? 188.731 208.071 196.439 1.00 37.12  ? 213 LYS F CD    1 
ATOM   7604 C CE    . LYS B 2 209 ? 188.068 206.752 196.662 1.00 37.12  ? 213 LYS F CE    1 
ATOM   7605 N NZ    . LYS B 2 209 ? 186.968 206.551 195.719 1.00 37.12  ? 213 LYS F NZ    1 
ATOM   7606 N N     . GLU B 2 210 ? 184.905 209.830 198.411 1.00 40.73  ? 214 GLU F N     1 
ATOM   7607 C CA    . GLU B 2 210 ? 183.633 210.107 197.756 1.00 40.73  ? 214 GLU F CA    1 
ATOM   7608 C C     . GLU B 2 210 ? 183.064 211.453 198.167 1.00 40.73  ? 214 GLU F C     1 
ATOM   7609 O O     . GLU B 2 210 ? 182.511 212.178 197.338 1.00 40.73  ? 214 GLU F O     1 
ATOM   7610 C CB    . GLU B 2 210 ? 182.623 209.015 198.081 1.00 40.73  ? 214 GLU F CB    1 
ATOM   7611 C CG    . GLU B 2 210 ? 182.972 207.667 197.541 1.00 40.73  ? 214 GLU F CG    1 
ATOM   7612 C CD    . GLU B 2 210 ? 181.884 206.661 197.807 1.00 40.73  ? 214 GLU F CD    1 
ATOM   7613 O OE1   . GLU B 2 210 ? 180.842 207.051 198.370 1.00 40.73  ? 214 GLU F OE1   1 
ATOM   7614 O OE2   . GLU B 2 210 ? 182.062 205.478 197.463 1.00 40.73  ? 214 GLU F OE2   1 
ATOM   7615 N N     . LYS B 2 211 ? 183.191 211.814 199.433 1.00 40.09  ? 215 LYS F N     1 
ATOM   7616 C CA    . LYS B 2 211 ? 182.470 212.975 199.916 1.00 40.09  ? 215 LYS F CA    1 
ATOM   7617 C C     . LYS B 2 211 ? 183.223 214.284 199.749 1.00 40.09  ? 215 LYS F C     1 
ATOM   7618 O O     . LYS B 2 211 ? 182.586 215.338 199.730 1.00 40.09  ? 215 LYS F O     1 
ATOM   7619 C CB    . LYS B 2 211 ? 182.109 212.779 201.386 1.00 40.09  ? 215 LYS F CB    1 
ATOM   7620 C CG    . LYS B 2 211 ? 180.833 213.455 201.787 1.00 40.09  ? 215 LYS F CG    1 
ATOM   7621 C CD    . LYS B 2 211 ? 180.318 212.937 203.117 1.00 40.09  ? 215 LYS F CD    1 
ATOM   7622 C CE    . LYS B 2 211 ? 180.110 211.434 203.088 1.00 40.09  ? 215 LYS F CE    1 
ATOM   7623 N NZ    . LYS B 2 211 ? 179.317 211.013 201.911 1.00 40.09  ? 215 LYS F NZ    1 
ATOM   7624 N N     . LEU B 2 212 ? 184.546 214.264 199.630 1.00 39.84  ? 216 LEU F N     1 
ATOM   7625 C CA    . LEU B 2 212 ? 185.292 215.511 199.633 1.00 39.84  ? 216 LEU F CA    1 
ATOM   7626 C C     . LEU B 2 212 ? 186.212 215.721 198.447 1.00 39.84  ? 216 LEU F C     1 
ATOM   7627 O O     . LEU B 2 212 ? 186.684 216.844 198.268 1.00 39.84  ? 216 LEU F O     1 
ATOM   7628 C CB    . LEU B 2 212 ? 186.142 215.633 200.906 1.00 39.84  ? 216 LEU F CB    1 
ATOM   7629 C CG    . LEU B 2 212 ? 185.415 215.797 202.234 1.00 39.84  ? 216 LEU F CG    1 
ATOM   7630 C CD1   . LEU B 2 212 ? 186.402 215.803 203.354 1.00 39.84  ? 216 LEU F CD1   1 
ATOM   7631 C CD2   . LEU B 2 212 ? 184.622 217.064 202.240 1.00 39.84  ? 216 LEU F CD2   1 
ATOM   7632 N N     . CYS B 2 213 ? 186.506 214.700 197.654 1.00 42.32  ? 217 CYS F N     1 
ATOM   7633 C CA    . CYS B 2 213 ? 187.503 214.865 196.611 1.00 42.32  ? 217 CYS F CA    1 
ATOM   7634 C C     . CYS B 2 213 ? 186.879 215.406 195.334 1.00 42.32  ? 217 CYS F C     1 
ATOM   7635 O O     . CYS B 2 213 ? 185.690 215.228 195.077 1.00 42.32  ? 217 CYS F O     1 
ATOM   7636 C CB    . CYS B 2 213 ? 188.208 213.543 196.332 1.00 42.32  ? 217 CYS F CB    1 
ATOM   7637 S SG    . CYS B 2 213 ? 189.468 213.134 197.540 1.00 42.32  ? 217 CYS F SG    1 
ATOM   7638 N N     . TYR B 2 214 ? 187.703 216.075 194.536 1.00 44.88  ? 218 TYR F N     1 
ATOM   7639 C CA    . TYR B 2 214 ? 187.281 216.642 193.267 1.00 44.88  ? 218 TYR F CA    1 
ATOM   7640 C C     . TYR B 2 214 ? 188.499 216.773 192.371 1.00 44.88  ? 218 TYR F C     1 
ATOM   7641 O O     . TYR B 2 214 ? 189.634 216.675 192.829 1.00 44.88  ? 218 TYR F O     1 
ATOM   7642 C CB    . TYR B 2 214 ? 186.609 217.998 193.452 1.00 44.88  ? 218 TYR F CB    1 
ATOM   7643 C CG    . TYR B 2 214 ? 187.541 219.089 193.897 1.00 44.88  ? 218 TYR F CG    1 
ATOM   7644 C CD1   . TYR B 2 214 ? 187.821 219.277 195.226 1.00 44.88  ? 218 TYR F CD1   1 
ATOM   7645 C CD2   . TYR B 2 214 ? 188.126 219.939 192.988 1.00 44.88  ? 218 TYR F CD2   1 
ATOM   7646 C CE1   . TYR B 2 214 ? 188.657 220.268 195.633 1.00 44.88  ? 218 TYR F CE1   1 
ATOM   7647 C CE2   . TYR B 2 214 ? 188.962 220.930 193.390 1.00 44.88  ? 218 TYR F CE2   1 
ATOM   7648 C CZ    . TYR B 2 214 ? 189.226 221.090 194.712 1.00 44.88  ? 218 TYR F CZ    1 
ATOM   7649 O OH    . TYR B 2 214 ? 190.067 222.085 195.119 1.00 44.88  ? 218 TYR F OH    1 
ATOM   7650 N N     . VAL B 2 215 ? 188.252 217.010 191.090 1.00 46.92  ? 219 VAL F N     1 
ATOM   7651 C CA    . VAL B 2 215 ? 189.310 217.120 190.095 1.00 46.92  ? 219 VAL F CA    1 
ATOM   7652 C C     . VAL B 2 215 ? 189.571 218.587 189.816 1.00 46.92  ? 219 VAL F C     1 
ATOM   7653 O O     . VAL B 2 215 ? 188.649 219.338 189.489 1.00 46.92  ? 219 VAL F O     1 
ATOM   7654 C CB    . VAL B 2 215 ? 188.937 216.380 188.806 1.00 46.92  ? 219 VAL F CB    1 
ATOM   7655 C CG1   . VAL B 2 215 ? 190.089 216.389 187.851 1.00 46.92  ? 219 VAL F CG1   1 
ATOM   7656 C CG2   . VAL B 2 215 ? 188.538 214.972 189.123 1.00 46.92  ? 219 VAL F CG2   1 
ATOM   7657 N N     . ALA B 2 216 ? 190.823 218.997 189.931 1.00 50.33  ? 220 ALA F N     1 
ATOM   7658 C CA    . ALA B 2 216 ? 191.186 220.374 189.655 1.00 50.33  ? 220 ALA F CA    1 
ATOM   7659 C C     . ALA B 2 216 ? 191.210 220.611 188.157 1.00 50.33  ? 220 ALA F C     1 
ATOM   7660 O O     . ALA B 2 216 ? 191.602 219.736 187.387 1.00 50.33  ? 220 ALA F O     1 
ATOM   7661 C CB    . ALA B 2 216 ? 192.553 220.695 190.246 1.00 50.33  ? 220 ALA F CB    1 
ATOM   7662 N N     . LEU B 2 217 ? 190.785 221.799 187.738 1.00 53.23  ? 221 LEU F N     1 
ATOM   7663 C CA    . LEU B 2 217 ? 190.870 222.114 186.319 1.00 53.23  ? 221 LEU F CA    1 
ATOM   7664 C C     . LEU B 2 217 ? 192.304 222.394 185.912 1.00 53.23  ? 221 LEU F C     1 
ATOM   7665 O O     . LEU B 2 217 ? 192.730 222.015 184.818 1.00 53.23  ? 221 LEU F O     1 
ATOM   7666 C CB    . LEU B 2 217 ? 189.981 223.301 185.975 1.00 53.23  ? 221 LEU F CB    1 
ATOM   7667 C CG    . LEU B 2 217 ? 189.735 223.429 184.477 1.00 53.23  ? 221 LEU F CG    1 
ATOM   7668 C CD1   . LEU B 2 217 ? 188.905 222.266 184.011 1.00 53.23  ? 221 LEU F CD1   1 
ATOM   7669 C CD2   . LEU B 2 217 ? 189.055 224.732 184.145 1.00 53.23  ? 221 LEU F CD2   1 
ATOM   7670 N N     . ASP B 2 218 ? 193.063 223.057 186.772 1.00 54.01  ? 222 ASP F N     1 
ATOM   7671 C CA    . ASP B 2 218 ? 194.479 223.300 186.546 1.00 54.01  ? 222 ASP F CA    1 
ATOM   7672 C C     . ASP B 2 218 ? 195.233 222.907 187.803 1.00 54.01  ? 222 ASP F C     1 
ATOM   7673 O O     . ASP B 2 218 ? 195.063 223.534 188.854 1.00 54.01  ? 222 ASP F O     1 
ATOM   7674 C CB    . ASP B 2 218 ? 194.736 224.761 186.197 1.00 54.01  ? 222 ASP F CB    1 
ATOM   7675 C CG    . ASP B 2 218 ? 196.017 224.953 185.443 1.00 54.01  ? 222 ASP F CG    1 
ATOM   7676 O OD1   . ASP B 2 218 ? 196.010 224.780 184.211 1.00 54.01  ? 222 ASP F OD1   1 
ATOM   7677 O OD2   . ASP B 2 218 ? 197.037 225.268 186.078 1.00 54.01  ? 222 ASP F OD2   1 
ATOM   7678 N N     . PHE B 2 219 ? 196.076 221.884 187.691 1.00 49.70  ? 223 PHE F N     1 
ATOM   7679 C CA    . PHE B 2 219 ? 196.672 221.298 188.882 1.00 49.70  ? 223 PHE F CA    1 
ATOM   7680 C C     . PHE B 2 219 ? 197.661 222.246 189.536 1.00 49.70  ? 223 PHE F C     1 
ATOM   7681 O O     . PHE B 2 219 ? 197.663 222.390 190.761 1.00 49.70  ? 223 PHE F O     1 
ATOM   7682 C CB    . PHE B 2 219 ? 197.347 219.981 188.532 1.00 49.70  ? 223 PHE F CB    1 
ATOM   7683 C CG    . PHE B 2 219 ? 197.832 219.219 189.719 1.00 49.70  ? 223 PHE F CG    1 
ATOM   7684 C CD1   . PHE B 2 219 ? 196.942 218.631 190.585 1.00 49.70  ? 223 PHE F CD1   1 
ATOM   7685 C CD2   . PHE B 2 219 ? 199.176 219.085 189.963 1.00 49.70  ? 223 PHE F CD2   1 
ATOM   7686 C CE1   . PHE B 2 219 ? 197.385 217.934 191.670 1.00 49.70  ? 223 PHE F CE1   1 
ATOM   7687 C CE2   . PHE B 2 219 ? 199.617 218.386 191.043 1.00 49.70  ? 223 PHE F CE2   1 
ATOM   7688 C CZ    . PHE B 2 219 ? 198.723 217.809 191.895 1.00 49.70  ? 223 PHE F CZ    1 
ATOM   7689 N N     . GLU B 2 220 ? 198.506 222.905 188.747 1.00 55.04  ? 224 GLU F N     1 
ATOM   7690 C CA    . GLU B 2 220 ? 199.506 223.788 189.333 1.00 55.04  ? 224 GLU F CA    1 
ATOM   7691 C C     . GLU B 2 220 ? 198.863 225.002 189.979 1.00 55.04  ? 224 GLU F C     1 
ATOM   7692 O O     . GLU B 2 220 ? 199.288 225.445 191.053 1.00 55.04  ? 224 GLU F O     1 
ATOM   7693 C CB    . GLU B 2 220 ? 200.508 224.218 188.272 1.00 55.04  ? 224 GLU F CB    1 
ATOM   7694 C CG    . GLU B 2 220 ? 201.341 223.077 187.779 1.00 55.04  ? 224 GLU F CG    1 
ATOM   7695 C CD    . GLU B 2 220 ? 201.948 222.295 188.920 1.00 55.04  ? 224 GLU F CD    1 
ATOM   7696 O OE1   . GLU B 2 220 ? 202.725 222.881 189.699 1.00 55.04  ? 224 GLU F OE1   1 
ATOM   7697 O OE2   . GLU B 2 220 ? 201.634 221.095 189.050 1.00 55.04  ? 224 GLU F OE2   1 
ATOM   7698 N N     . ASN B 2 221 ? 197.831 225.549 189.351 1.00 55.38  ? 225 ASN F N     1 
ATOM   7699 C CA    . ASN B 2 221 ? 197.178 226.706 189.937 1.00 55.38  ? 225 ASN F CA    1 
ATOM   7700 C C     . ASN B 2 221 ? 196.421 226.329 191.195 1.00 55.38  ? 225 ASN F C     1 
ATOM   7701 O O     . ASN B 2 221 ? 196.395 227.100 192.155 1.00 55.38  ? 225 ASN F O     1 
ATOM   7702 C CB    . ASN B 2 221 ? 196.259 227.363 188.917 1.00 55.38  ? 225 ASN F CB    1 
ATOM   7703 C CG    . ASN B 2 221 ? 197.029 228.058 187.829 1.00 55.38  ? 225 ASN F CG    1 
ATOM   7704 O OD1   . ASN B 2 221 ? 196.724 227.921 186.647 1.00 55.38  ? 225 ASN F OD1   1 
ATOM   7705 N ND2   . ASN B 2 221 ? 198.053 228.802 188.221 1.00 55.38  ? 225 ASN F ND2   1 
ATOM   7706 N N     . GLU B 2 222 ? 195.819 225.141 191.231 1.00 53.37  ? 226 GLU F N     1 
ATOM   7707 C CA    . GLU B 2 222 ? 195.159 224.732 192.465 1.00 53.37  ? 226 GLU F CA    1 
ATOM   7708 C C     . GLU B 2 222 ? 196.172 224.424 193.558 1.00 53.37  ? 226 GLU F C     1 
ATOM   7709 O O     . GLU B 2 222 ? 195.905 224.665 194.738 1.00 53.37  ? 226 GLU F O     1 
ATOM   7710 C CB    . GLU B 2 222 ? 194.249 223.544 192.211 1.00 53.37  ? 226 GLU F CB    1 
ATOM   7711 C CG    . GLU B 2 222 ? 192.934 223.942 191.588 1.00 53.37  ? 226 GLU F CG    1 
ATOM   7712 C CD    . GLU B 2 222 ? 191.781 223.879 192.561 1.00 53.37  ? 226 GLU F CD    1 
ATOM   7713 O OE1   . GLU B 2 222 ? 192.032 223.709 193.766 1.00 53.37  ? 226 GLU F OE1   1 
ATOM   7714 O OE2   . GLU B 2 222 ? 190.619 223.997 192.125 1.00 53.37  ? 226 GLU F OE2   1 
ATOM   7715 N N     . MET B 2 223 ? 197.351 223.924 193.195 1.00 53.50  ? 227 MET F N     1 
ATOM   7716 C CA    . MET B 2 223 ? 198.379 223.708 194.205 1.00 53.50  ? 227 MET F CA    1 
ATOM   7717 C C     . MET B 2 223 ? 198.847 225.026 194.796 1.00 53.50  ? 227 MET F C     1 
ATOM   7718 O O     . MET B 2 223 ? 198.999 225.148 196.016 1.00 53.50  ? 227 MET F O     1 
ATOM   7719 C CB    . MET B 2 223 ? 199.555 222.935 193.617 1.00 53.50  ? 227 MET F CB    1 
ATOM   7720 C CG    . MET B 2 223 ? 199.250 221.475 193.357 1.00 53.50  ? 227 MET F CG    1 
ATOM   7721 S SD    . MET B 2 223 ? 198.899 220.523 194.844 1.00 53.50  ? 227 MET F SD    1 
ATOM   7722 C CE    . MET B 2 223 ? 200.534 219.952 195.262 1.00 53.50  ? 227 MET F CE    1 
ATOM   7723 N N     . ALA B 2 224 ? 199.068 226.031 193.952 1.00 55.08  ? 228 ALA F N     1 
ATOM   7724 C CA    . ALA B 2 224 ? 199.441 227.341 194.473 1.00 55.08  ? 228 ALA F CA    1 
ATOM   7725 C C     . ALA B 2 224 ? 198.319 227.964 195.296 1.00 55.08  ? 228 ALA F C     1 
ATOM   7726 O O     . ALA B 2 224 ? 198.580 228.598 196.326 1.00 55.08  ? 228 ALA F O     1 
ATOM   7727 C CB    . ALA B 2 224 ? 199.837 228.261 193.326 1.00 55.08  ? 228 ALA F CB    1 
ATOM   7728 N N     . THR B 2 225 ? 197.069 227.788 194.869 1.00 55.33  ? 229 THR F N     1 
ATOM   7729 C CA    . THR B 2 225 ? 195.942 228.303 195.634 1.00 55.33  ? 229 THR F CA    1 
ATOM   7730 C C     . THR B 2 225 ? 195.878 227.670 197.014 1.00 55.33  ? 229 THR F C     1 
ATOM   7731 O O     . THR B 2 225 ? 195.638 228.362 198.005 1.00 55.33  ? 229 THR F O     1 
ATOM   7732 C CB    . THR B 2 225 ? 194.639 228.061 194.875 1.00 55.33  ? 229 THR F CB    1 
ATOM   7733 O OG1   . THR B 2 225 ? 194.593 228.907 193.722 1.00 55.33  ? 229 THR F OG1   1 
ATOM   7734 C CG2   . THR B 2 225 ? 193.448 228.368 195.742 1.00 55.33  ? 229 THR F CG2   1 
ATOM   7735 N N     . ALA B 2 226 ? 196.083 226.360 197.104 1.00 54.33  ? 230 ALA F N     1 
ATOM   7736 C CA    . ALA B 2 226 ? 196.071 225.725 198.413 1.00 54.33  ? 230 ALA F CA    1 
ATOM   7737 C C     . ALA B 2 226 ? 197.275 226.136 199.241 1.00 54.33  ? 230 ALA F C     1 
ATOM   7738 O O     . ALA B 2 226 ? 197.172 226.248 200.466 1.00 54.33  ? 230 ALA F O     1 
ATOM   7739 C CB    . ALA B 2 226 ? 196.024 224.207 198.272 1.00 54.33  ? 230 ALA F CB    1 
ATOM   7740 N N     . ALA B 2 227 ? 198.418 226.370 198.599 1.00 56.89  ? 231 ALA F N     1 
ATOM   7741 C CA    . ALA B 2 227 ? 199.601 226.788 199.336 1.00 56.89  ? 231 ALA F CA    1 
ATOM   7742 C C     . ALA B 2 227 ? 199.477 228.199 199.885 1.00 56.89  ? 231 ALA F C     1 
ATOM   7743 O O     . ALA B 2 227 ? 200.121 228.518 200.888 1.00 56.89  ? 231 ALA F O     1 
ATOM   7744 C CB    . ALA B 2 227 ? 200.839 226.693 198.448 1.00 56.89  ? 231 ALA F CB    1 
ATOM   7745 N N     . SER B 2 228 ? 198.670 229.052 199.261 1.00 58.47  ? 232 SER F N     1 
ATOM   7746 C CA    . SER B 2 228 ? 198.548 230.430 199.715 1.00 58.47  ? 232 SER F CA    1 
ATOM   7747 C C     . SER B 2 228 ? 197.295 230.656 200.550 1.00 58.47  ? 232 SER F C     1 
ATOM   7748 O O     . SER B 2 228 ? 197.386 231.073 201.707 1.00 58.47  ? 232 SER F O     1 
ATOM   7749 C CB    . SER B 2 228 ? 198.561 231.376 198.509 1.00 58.47  ? 232 SER F CB    1 
ATOM   7750 O OG    . SER B 2 228 ? 197.271 231.483 197.938 1.00 58.47  ? 232 SER F OG    1 
ATOM   7751 N N     . SER B 2 229 ? 196.123 230.370 200.000 1.00 59.18  ? 233 SER F N     1 
ATOM   7752 C CA    . SER B 2 229 ? 194.867 230.569 200.702 1.00 59.18  ? 233 SER F CA    1 
ATOM   7753 C C     . SER B 2 229 ? 194.674 229.499 201.770 1.00 59.18  ? 233 SER F C     1 
ATOM   7754 O O     . SER B 2 229 ? 195.585 228.746 202.119 1.00 59.18  ? 233 SER F O     1 
ATOM   7755 C CB    . SER B 2 229 ? 193.705 230.537 199.715 1.00 59.18  ? 233 SER F CB    1 
ATOM   7756 O OG    . SER B 2 229 ? 192.460 230.538 200.388 1.00 59.18  ? 233 SER F OG    1 
ATOM   7757 N N     . SER B 2 230 ? 193.462 229.465 202.320 1.00 57.02  ? 234 SER F N     1 
ATOM   7758 C CA    . SER B 2 230 ? 193.007 228.327 203.106 1.00 57.02  ? 234 SER F CA    1 
ATOM   7759 C C     . SER B 2 230 ? 191.537 228.037 202.835 1.00 57.02  ? 234 SER F C     1 
ATOM   7760 O O     . SER B 2 230 ? 190.886 227.367 203.641 1.00 57.02  ? 234 SER F O     1 
ATOM   7761 C CB    . SER B 2 230 ? 193.229 228.562 204.596 1.00 57.02  ? 234 SER F CB    1 
ATOM   7762 O OG    . SER B 2 230 ? 193.200 227.343 205.312 1.00 57.02  ? 234 SER F OG    1 
ATOM   7763 N N     . SER B 2 231 ? 191.003 228.533 201.723 1.00 55.75  ? 235 SER F N     1 
ATOM   7764 C CA    . SER B 2 231 ? 189.596 228.394 201.377 1.00 55.75  ? 235 SER F CA    1 
ATOM   7765 C C     . SER B 2 231 ? 189.246 227.023 200.826 1.00 55.75  ? 235 SER F C     1 
ATOM   7766 O O     . SER B 2 231 ? 188.071 226.769 200.544 1.00 55.75  ? 235 SER F O     1 
ATOM   7767 C CB    . SER B 2 231 ? 189.218 229.461 200.358 1.00 55.75  ? 235 SER F CB    1 
ATOM   7768 O OG    . SER B 2 231 ? 190.237 229.585 199.387 1.00 55.75  ? 235 SER F OG    1 
ATOM   7769 N N     . LEU B 2 232 ? 190.229 226.145 200.661 1.00 52.24  ? 236 LEU F N     1 
ATOM   7770 C CA    . LEU B 2 232 ? 190.021 224.827 200.085 1.00 52.24  ? 236 LEU F CA    1 
ATOM   7771 C C     . LEU B 2 232 ? 189.746 223.757 201.121 1.00 52.24  ? 236 LEU F C     1 
ATOM   7772 O O     . LEU B 2 232 ? 189.238 222.693 200.762 1.00 52.24  ? 236 LEU F O     1 
ATOM   7773 C CB    . LEU B 2 232 ? 191.239 224.424 199.261 1.00 52.24  ? 236 LEU F CB    1 
ATOM   7774 C CG    . LEU B 2 232 ? 191.251 224.870 197.802 1.00 52.24  ? 236 LEU F CG    1 
ATOM   7775 C CD1   . LEU B 2 232 ? 191.228 226.369 197.679 1.00 52.24  ? 236 LEU F CD1   1 
ATOM   7776 C CD2   . LEU B 2 232 ? 192.499 224.326 197.154 1.00 52.24  ? 236 LEU F CD2   1 
ATOM   7777 N N     . GLU B 2 233 ? 190.037 224.017 202.386 1.00 50.40  ? 237 GLU F N     1 
ATOM   7778 C CA    . GLU B 2 233 ? 190.013 222.975 203.396 1.00 50.40  ? 237 GLU F CA    1 
ATOM   7779 C C     . GLU B 2 233 ? 188.600 222.703 203.880 1.00 50.40  ? 237 GLU F C     1 
ATOM   7780 O O     . GLU B 2 233 ? 187.885 223.619 204.285 1.00 50.40  ? 237 GLU F O     1 
ATOM   7781 C CB    . GLU B 2 233 ? 190.899 223.373 204.565 1.00 50.40  ? 237 GLU F CB    1 
ATOM   7782 C CG    . GLU B 2 233 ? 192.339 223.481 204.176 1.00 50.40  ? 237 GLU F CG    1 
ATOM   7783 C CD    . GLU B 2 233 ? 193.205 223.958 205.301 1.00 50.40  ? 237 GLU F CD    1 
ATOM   7784 O OE1   . GLU B 2 233 ? 192.847 224.980 205.922 1.00 50.40  ? 237 GLU F OE1   1 
ATOM   7785 O OE2   . GLU B 2 233 ? 194.238 223.309 205.573 1.00 50.40  ? 237 GLU F OE2   1 
ATOM   7786 N N     . LYS B 2 234 ? 188.207 221.439 203.840 1.00 46.62  ? 238 LYS F N     1 
ATOM   7787 C CA    . LYS B 2 234 ? 186.968 220.975 204.426 1.00 46.62  ? 238 LYS F CA    1 
ATOM   7788 C C     . LYS B 2 234 ? 187.297 220.105 205.624 1.00 46.62  ? 238 LYS F C     1 
ATOM   7789 O O     . LYS B 2 234 ? 188.423 219.640 205.782 1.00 46.62  ? 238 LYS F O     1 
ATOM   7790 C CB    . LYS B 2 234 ? 186.133 220.171 203.434 1.00 46.62  ? 238 LYS F CB    1 
ATOM   7791 C CG    . LYS B 2 234 ? 185.793 220.892 202.169 1.00 46.62  ? 238 LYS F CG    1 
ATOM   7792 C CD    . LYS B 2 234 ? 184.672 221.877 202.361 1.00 46.62  ? 238 LYS F CD    1 
ATOM   7793 C CE    . LYS B 2 234 ? 184.278 222.492 201.030 1.00 46.62  ? 238 LYS F CE    1 
ATOM   7794 N NZ    . LYS B 2 234 ? 183.309 223.602 201.178 1.00 46.62  ? 238 LYS F NZ    1 
ATOM   7795 N N     . SER B 2 235 ? 186.306 219.899 206.475 1.00 43.46  ? 239 SER F N     1 
ATOM   7796 C CA    . SER B 2 235 ? 186.441 219.025 207.624 1.00 43.46  ? 239 SER F CA    1 
ATOM   7797 C C     . SER B 2 235 ? 185.526 217.825 207.463 1.00 43.46  ? 239 SER F C     1 
ATOM   7798 O O     . SER B 2 235 ? 184.469 217.908 206.839 1.00 43.46  ? 239 SER F O     1 
ATOM   7799 C CB    . SER B 2 235 ? 186.107 219.759 208.917 1.00 43.46  ? 239 SER F CB    1 
ATOM   7800 O OG    . SER B 2 235 ? 187.003 220.828 209.128 1.00 43.46  ? 239 SER F OG    1 
ATOM   7801 N N     . TYR B 2 236 ? 185.944 216.708 208.028 1.00 41.05  ? 240 TYR F N     1 
ATOM   7802 C CA    . TYR B 2 236 ? 185.180 215.477 207.977 1.00 41.05  ? 240 TYR F CA    1 
ATOM   7803 C C     . TYR B 2 236 ? 185.091 214.921 209.384 1.00 41.05  ? 240 TYR F C     1 
ATOM   7804 O O     . TYR B 2 236 ? 185.973 215.148 210.207 1.00 41.05  ? 240 TYR F O     1 
ATOM   7805 C CB    . TYR B 2 236 ? 185.825 214.465 207.030 1.00 41.05  ? 240 TYR F CB    1 
ATOM   7806 C CG    . TYR B 2 236 ? 185.042 213.194 206.848 1.00 41.05  ? 240 TYR F CG    1 
ATOM   7807 C CD1   . TYR B 2 236 ? 183.974 213.137 205.982 1.00 41.05  ? 240 TYR F CD1   1 
ATOM   7808 C CD2   . TYR B 2 236 ? 185.384 212.052 207.530 1.00 41.05  ? 240 TYR F CD2   1 
ATOM   7809 C CE1   . TYR B 2 236 ? 183.271 211.987 205.816 1.00 41.05  ? 240 TYR F CE1   1 
ATOM   7810 C CE2   . TYR B 2 236 ? 184.682 210.902 207.371 1.00 41.05  ? 240 TYR F CE2   1 
ATOM   7811 C CZ    . TYR B 2 236 ? 183.627 210.872 206.513 1.00 41.05  ? 240 TYR F CZ    1 
ATOM   7812 O OH    . TYR B 2 236 ? 182.922 209.709 206.353 1.00 41.05  ? 240 TYR F OH    1 
ATOM   7813 N N     . GLU B 2 237 ? 184.026 214.196 209.654 1.00 44.31  ? 241 GLU F N     1 
ATOM   7814 C CA    . GLU B 2 237 ? 183.704 213.740 210.997 1.00 44.31  ? 241 GLU F CA    1 
ATOM   7815 C C     . GLU B 2 237 ? 183.837 212.227 211.051 1.00 44.31  ? 241 GLU F C     1 
ATOM   7816 O O     . GLU B 2 237 ? 182.989 211.504 210.522 1.00 44.31  ? 241 GLU F O     1 
ATOM   7817 C CB    . GLU B 2 237 ? 182.296 214.180 211.369 1.00 44.31  ? 241 GLU F CB    1 
ATOM   7818 C CG    . GLU B 2 237 ? 181.715 213.462 212.548 1.00 44.31  ? 241 GLU F CG    1 
ATOM   7819 C CD    . GLU B 2 237 ? 182.189 214.034 213.840 1.00 44.31  ? 241 GLU F CD    1 
ATOM   7820 O OE1   . GLU B 2 237 ? 182.783 215.126 213.810 1.00 44.31  ? 241 GLU F OE1   1 
ATOM   7821 O OE2   . GLU B 2 237 ? 181.962 213.396 214.884 1.00 44.31  ? 241 GLU F OE2   1 
ATOM   7822 N N     . LEU B 2 238 ? 184.888 211.751 211.695 1.00 40.93  ? 242 LEU F N     1 
ATOM   7823 C CA    . LEU B 2 238 ? 185.146 210.322 211.785 1.00 40.93  ? 242 LEU F CA    1 
ATOM   7824 C C     . LEU B 2 238 ? 184.030 209.651 212.573 1.00 40.93  ? 242 LEU F C     1 
ATOM   7825 O O     . LEU B 2 238 ? 183.242 210.339 213.228 1.00 40.93  ? 242 LEU F O     1 
ATOM   7826 C CB    . LEU B 2 238 ? 186.506 210.075 212.426 1.00 40.93  ? 242 LEU F CB    1 
ATOM   7827 C CG    . LEU B 2 238 ? 187.676 210.659 211.649 1.00 40.93  ? 242 LEU F CG    1 
ATOM   7828 C CD1   . LEU B 2 238 ? 188.972 210.114 212.172 1.00 40.93  ? 242 LEU F CD1   1 
ATOM   7829 C CD2   . LEU B 2 238 ? 187.531 210.344 210.194 1.00 40.93  ? 242 LEU F CD2   1 
ATOM   7830 N N     . PRO B 2 239 ? 183.915 208.334 212.539 1.00 41.44  ? 243 PRO F N     1 
ATOM   7831 C CA    . PRO B 2 239 ? 182.806 207.682 213.242 1.00 41.44  ? 243 PRO F CA    1 
ATOM   7832 C C     . PRO B 2 239 ? 182.955 207.655 214.754 1.00 41.44  ? 243 PRO F C     1 
ATOM   7833 O O     . PRO B 2 239 ? 182.250 206.901 215.429 1.00 41.44  ? 243 PRO F O     1 
ATOM   7834 C CB    . PRO B 2 239 ? 182.814 206.269 212.657 1.00 41.44  ? 243 PRO F CB    1 
ATOM   7835 C CG    . PRO B 2 239 ? 184.164 206.079 212.160 1.00 41.44  ? 243 PRO F CG    1 
ATOM   7836 C CD    . PRO B 2 239 ? 184.607 207.395 211.650 1.00 41.44  ? 243 PRO F CD    1 
ATOM   7837 N N     . ASP B 2 240 ? 183.880 208.445 215.299 1.00 42.20  ? 244 ASP F N     1 
ATOM   7838 C CA    . ASP B 2 240 ? 183.992 208.577 216.745 1.00 42.20  ? 244 ASP F CA    1 
ATOM   7839 C C     . ASP B 2 240 ? 184.258 210.007 217.182 1.00 42.20  ? 244 ASP F C     1 
ATOM   7840 O O     . ASP B 2 240 ? 184.687 210.214 218.318 1.00 42.20  ? 244 ASP F O     1 
ATOM   7841 C CB    . ASP B 2 240 ? 185.093 207.677 217.291 1.00 42.20  ? 244 ASP F CB    1 
ATOM   7842 C CG    . ASP B 2 240 ? 186.473 208.169 216.936 1.00 42.20  ? 244 ASP F CG    1 
ATOM   7843 O OD1   . ASP B 2 240 ? 186.702 208.477 215.756 1.00 42.20  ? 244 ASP F OD1   1 
ATOM   7844 O OD2   . ASP B 2 240 ? 187.334 208.256 217.833 1.00 42.20  ? 244 ASP F OD2   1 
ATOM   7845 N N     . GLY B 2 241 ? 184.020 210.993 216.330 1.00 42.47  ? 245 GLY F N     1 
ATOM   7846 C CA    . GLY B 2 241 ? 184.361 212.360 216.650 1.00 42.47  ? 245 GLY F CA    1 
ATOM   7847 C C     . GLY B 2 241 ? 185.665 212.730 215.988 1.00 42.47  ? 245 GLY F C     1 
ATOM   7848 O O     . GLY B 2 241 ? 185.969 212.229 214.908 1.00 42.47  ? 245 GLY F O     1 
ATOM   7849 N N     . GLN B 2 242 ? 186.447 213.593 216.626 1.00 45.71  ? 246 GLN F N     1 
ATOM   7850 C CA    . GLN B 2 242 ? 187.790 213.961 216.175 1.00 45.71  ? 246 GLN F CA    1 
ATOM   7851 C C     . GLN B 2 242 ? 187.858 214.284 214.681 1.00 45.71  ? 246 GLN F C     1 
ATOM   7852 O O     . GLN B 2 242 ? 188.452 213.571 213.882 1.00 45.71  ? 246 GLN F O     1 
ATOM   7853 C CB    . GLN B 2 242 ? 188.837 212.912 216.571 1.00 45.71  ? 246 GLN F CB    1 
ATOM   7854 C CG    . GLN B 2 242 ? 188.600 211.483 216.160 1.00 45.71  ? 246 GLN F CG    1 
ATOM   7855 C CD    . GLN B 2 242 ? 189.578 210.543 216.815 1.00 45.71  ? 246 GLN F CD    1 
ATOM   7856 O OE1   . GLN B 2 242 ? 190.383 210.952 217.646 1.00 45.71  ? 246 GLN F OE1   1 
ATOM   7857 N NE2   . GLN B 2 242 ? 189.511 209.275 216.451 1.00 45.71  ? 246 GLN F NE2   1 
ATOM   7858 N N     . VAL B 2 243 ? 187.157 215.355 214.325 1.00 43.47  ? 247 VAL F N     1 
ATOM   7859 C CA    . VAL B 2 243 ? 187.161 215.871 212.963 1.00 43.47  ? 247 VAL F CA    1 
ATOM   7860 C C     . VAL B 2 243 ? 188.569 215.956 212.392 1.00 43.47  ? 247 VAL F C     1 
ATOM   7861 O O     . VAL B 2 243 ? 189.529 216.262 213.105 1.00 43.47  ? 247 VAL F O     1 
ATOM   7862 C CB    . VAL B 2 243 ? 186.468 217.239 212.880 1.00 43.47  ? 247 VAL F CB    1 
ATOM   7863 C CG1   . VAL B 2 243 ? 185.115 217.161 213.503 1.00 43.47  ? 247 VAL F CG1   1 
ATOM   7864 C CG2   . VAL B 2 243 ? 187.289 218.288 213.565 1.00 43.47  ? 247 VAL F CG2   1 
ATOM   7865 N N     . ILE B 2 244 ? 188.697 215.668 211.102 1.00 41.65  ? 248 ILE F N     1 
ATOM   7866 C CA    . ILE B 2 244 ? 189.945 215.809 210.371 1.00 41.65  ? 248 ILE F CA    1 
ATOM   7867 C C     . ILE B 2 244 ? 189.736 216.852 209.286 1.00 41.65  ? 248 ILE F C     1 
ATOM   7868 O O     . ILE B 2 244 ? 188.651 216.946 208.709 1.00 41.65  ? 248 ILE F O     1 
ATOM   7869 C CB    . ILE B 2 244 ? 190.406 214.468 209.769 1.00 41.65  ? 248 ILE F CB    1 
ATOM   7870 C CG1   . ILE B 2 244 ? 189.490 214.030 208.640 1.00 41.65  ? 248 ILE F CG1   1 
ATOM   7871 C CG2   . ILE B 2 244 ? 190.404 213.394 210.813 1.00 41.65  ? 248 ILE F CG2   1 
ATOM   7872 C CD1   . ILE B 2 244 ? 190.023 212.869 207.886 1.00 41.65  ? 248 ILE F CD1   1 
ATOM   7873 N N     . THR B 2 245 ? 190.761 217.654 209.028 1.00 42.70  ? 249 THR F N     1 
ATOM   7874 C CA    . THR B 2 245 ? 190.692 218.692 208.010 1.00 42.70  ? 249 THR F CA    1 
ATOM   7875 C C     . THR B 2 245 ? 191.737 218.415 206.944 1.00 42.70  ? 249 THR F C     1 
ATOM   7876 O O     . THR B 2 245 ? 192.922 218.271 207.253 1.00 42.70  ? 249 THR F O     1 
ATOM   7877 C CB    . THR B 2 245 ? 190.886 220.083 208.612 1.00 42.70  ? 249 THR F CB    1 
ATOM   7878 O OG1   . THR B 2 245 ? 190.997 221.046 207.561 1.00 42.70  ? 249 THR F OG1   1 
ATOM   7879 C CG2   . THR B 2 245 ? 192.113 220.142 209.475 1.00 42.70  ? 249 THR F CG2   1 
ATOM   7880 N N     . ILE B 2 246 ? 191.297 218.335 205.694 1.00 42.19  ? 250 ILE F N     1 
ATOM   7881 C CA    . ILE B 2 246 ? 192.171 218.022 204.576 1.00 42.19  ? 250 ILE F CA    1 
ATOM   7882 C C     . ILE B 2 246 ? 192.180 219.197 203.614 1.00 42.19  ? 250 ILE F C     1 
ATOM   7883 O O     . ILE B 2 246 ? 191.146 219.819 203.365 1.00 42.19  ? 250 ILE F O     1 
ATOM   7884 C CB    . ILE B 2 246 ? 191.740 216.723 203.875 1.00 42.19  ? 250 ILE F CB    1 
ATOM   7885 C CG1   . ILE B 2 246 ? 190.378 216.870 203.229 1.00 42.19  ? 250 ILE F CG1   1 
ATOM   7886 C CG2   . ILE B 2 246 ? 191.638 215.614 204.878 1.00 42.19  ? 250 ILE F CG2   1 
ATOM   7887 C CD1   . ILE B 2 246 ? 189.988 215.662 202.462 1.00 42.19  ? 250 ILE F CD1   1 
ATOM   7888 N N     . GLY B 2 247 ? 193.355 219.516 203.097 1.00 43.05  ? 251 GLY F N     1 
ATOM   7889 C CA    . GLY B 2 247 ? 193.501 220.648 202.213 1.00 43.05  ? 251 GLY F CA    1 
ATOM   7890 C C     . GLY B 2 247 ? 193.686 220.233 200.775 1.00 43.05  ? 251 GLY F C     1 
ATOM   7891 O O     . GLY B 2 247 ? 192.737 219.789 200.131 1.00 43.05  ? 251 GLY F O     1 
ATOM   7892 N N     . ASN B 2 248 ? 194.905 220.357 200.256 1.00 43.50  ? 252 ASN F N     1 
ATOM   7893 C CA    . ASN B 2 248 ? 195.119 219.998 198.863 1.00 43.50  ? 252 ASN F CA    1 
ATOM   7894 C C     . ASN B 2 248 ? 195.007 218.512 198.609 1.00 43.50  ? 252 ASN F C     1 
ATOM   7895 O O     . ASN B 2 248 ? 195.082 218.107 197.454 1.00 43.50  ? 252 ASN F O     1 
ATOM   7896 C CB    . ASN B 2 248 ? 196.476 220.496 198.380 1.00 43.50  ? 252 ASN F CB    1 
ATOM   7897 C CG    . ASN B 2 248 ? 197.616 219.973 199.200 1.00 43.50  ? 252 ASN F CG    1 
ATOM   7898 O OD1   . ASN B 2 248 ? 197.487 218.988 199.912 1.00 43.50  ? 252 ASN F OD1   1 
ATOM   7899 N ND2   . ASN B 2 248 ? 198.756 220.633 199.099 1.00 43.50  ? 252 ASN F ND2   1 
ATOM   7900 N N     . GLU B 2 249 ? 194.840 217.688 199.636 1.00 41.93  ? 253 GLU F N     1 
ATOM   7901 C CA    . GLU B 2 249 ? 194.588 216.278 199.398 1.00 41.93  ? 253 GLU F CA    1 
ATOM   7902 C C     . GLU B 2 249 ? 193.278 216.042 198.684 1.00 41.93  ? 253 GLU F C     1 
ATOM   7903 O O     . GLU B 2 249 ? 193.061 214.938 198.186 1.00 41.93  ? 253 GLU F O     1 
ATOM   7904 C CB    . GLU B 2 249 ? 194.576 215.505 200.710 1.00 41.93  ? 253 GLU F CB    1 
ATOM   7905 C CG    . GLU B 2 249 ? 195.924 215.332 201.345 1.00 41.93  ? 253 GLU F CG    1 
ATOM   7906 C CD    . GLU B 2 249 ? 196.263 216.448 202.291 1.00 41.93  ? 253 GLU F CD    1 
ATOM   7907 O OE1   . GLU B 2 249 ? 195.372 217.263 202.578 1.00 41.93  ? 253 GLU F OE1   1 
ATOM   7908 O OE2   . GLU B 2 249 ? 197.421 216.512 202.750 1.00 41.93  ? 253 GLU F OE2   1 
ATOM   7909 N N     . ARG B 2 250 ? 192.399 217.040 198.634 1.00 41.59  ? 254 ARG F N     1 
ATOM   7910 C CA    . ARG B 2 250 ? 191.094 216.839 198.026 1.00 41.59  ? 254 ARG F CA    1 
ATOM   7911 C C     . ARG B 2 250 ? 191.212 216.653 196.525 1.00 41.59  ? 254 ARG F C     1 
ATOM   7912 O O     . ARG B 2 250 ? 190.555 215.784 195.950 1.00 41.59  ? 254 ARG F O     1 
ATOM   7913 C CB    . ARG B 2 250 ? 190.191 218.017 198.338 1.00 41.59  ? 254 ARG F CB    1 
ATOM   7914 C CG    . ARG B 2 250 ? 190.043 218.293 199.789 1.00 41.59  ? 254 ARG F CG    1 
ATOM   7915 C CD    . ARG B 2 250 ? 189.233 219.527 199.972 1.00 41.59  ? 254 ARG F CD    1 
ATOM   7916 N NE    . ARG B 2 250 ? 187.956 219.400 199.297 1.00 41.59  ? 254 ARG F NE    1 
ATOM   7917 C CZ    . ARG B 2 250 ? 187.207 220.427 198.943 1.00 41.59  ? 254 ARG F CZ    1 
ATOM   7918 N NH1   . ARG B 2 250 ? 187.621 221.652 199.187 1.00 41.59  ? 254 ARG F NH1   1 
ATOM   7919 N NH2   . ARG B 2 250 ? 186.055 220.227 198.336 1.00 41.59  ? 254 ARG F NH2   1 
ATOM   7920 N N     . PHE B 2 251 ? 192.038 217.459 195.873 1.00 42.86  ? 255 PHE F N     1 
ATOM   7921 C CA    . PHE B 2 251 ? 192.239 217.343 194.443 1.00 42.86  ? 255 PHE F CA    1 
ATOM   7922 C C     . PHE B 2 251 ? 193.523 216.626 194.088 1.00 42.86  ? 255 PHE F C     1 
ATOM   7923 O O     . PHE B 2 251 ? 193.765 216.372 192.910 1.00 42.86  ? 255 PHE F O     1 
ATOM   7924 C CB    . PHE B 2 251 ? 192.220 218.720 193.787 1.00 42.86  ? 255 PHE F CB    1 
ATOM   7925 C CG    . PHE B 2 251 ? 193.263 219.645 194.296 1.00 42.86  ? 255 PHE F CG    1 
ATOM   7926 C CD1   . PHE B 2 251 ? 194.528 219.631 193.770 1.00 42.86  ? 255 PHE F CD1   1 
ATOM   7927 C CD2   . PHE B 2 251 ? 192.972 220.544 195.287 1.00 42.86  ? 255 PHE F CD2   1 
ATOM   7928 C CE1   . PHE B 2 251 ? 195.475 220.477 194.229 1.00 42.86  ? 255 PHE F CE1   1 
ATOM   7929 C CE2   . PHE B 2 251 ? 193.920 221.391 195.744 1.00 42.86  ? 255 PHE F CE2   1 
ATOM   7930 C CZ    . PHE B 2 251 ? 195.173 221.359 195.214 1.00 42.86  ? 255 PHE F CZ    1 
ATOM   7931 N N     . ARG B 2 252 ? 194.350 216.296 195.068 1.00 39.06  ? 256 ARG F N     1 
ATOM   7932 C CA    . ARG B 2 252 ? 195.573 215.558 194.803 1.00 39.06  ? 256 ARG F CA    1 
ATOM   7933 C C     . ARG B 2 252 ? 195.330 214.068 194.677 1.00 39.06  ? 256 ARG F C     1 
ATOM   7934 O O     . ARG B 2 252 ? 196.161 213.368 194.104 1.00 39.06  ? 256 ARG F O     1 
ATOM   7935 C CB    . ARG B 2 252 ? 196.581 215.823 195.912 1.00 39.06  ? 256 ARG F CB    1 
ATOM   7936 C CG    . ARG B 2 252 ? 197.991 215.755 195.484 1.00 39.06  ? 256 ARG F CG    1 
ATOM   7937 C CD    . ARG B 2 252 ? 198.808 216.803 196.186 1.00 39.06  ? 256 ARG F CD    1 
ATOM   7938 N NE    . ARG B 2 252 ? 198.969 216.547 197.609 1.00 39.06  ? 256 ARG F NE    1 
ATOM   7939 C CZ    . ARG B 2 252 ? 199.907 215.764 198.124 1.00 39.06  ? 256 ARG F CZ    1 
ATOM   7940 N NH1   . ARG B 2 252 ? 200.762 215.140 197.335 1.00 39.06  ? 256 ARG F NH1   1 
ATOM   7941 N NH2   . ARG B 2 252 ? 199.987 215.598 199.430 1.00 39.06  ? 256 ARG F NH2   1 
ATOM   7942 N N     . CYS B 2 253 ? 194.213 213.566 195.199 1.00 38.71  ? 257 CYS F N     1 
ATOM   7943 C CA    . CYS B 2 253 ? 193.929 212.138 195.067 1.00 38.71  ? 257 CYS F CA    1 
ATOM   7944 C C     . CYS B 2 253 ? 193.449 211.781 193.668 1.00 38.71  ? 257 CYS F C     1 
ATOM   7945 O O     . CYS B 2 253 ? 194.087 210.942 193.013 1.00 38.71  ? 257 CYS F O     1 
ATOM   7946 C CB    . CYS B 2 253 ? 192.944 211.698 196.149 1.00 38.71  ? 257 CYS F CB    1 
ATOM   7947 S SG    . CYS B 2 253 ? 192.243 210.082 195.881 1.00 38.71  ? 257 CYS F SG    1 
ATOM   7948 N N     . PRO B 2 254 ? 192.368 212.365 193.139 1.00 38.84  ? 258 PRO F N     1 
ATOM   7949 C CA    . PRO B 2 254 ? 191.909 211.951 191.811 1.00 38.84  ? 258 PRO F CA    1 
ATOM   7950 C C     . PRO B 2 254 ? 192.790 212.438 190.686 1.00 38.84  ? 258 PRO F C     1 
ATOM   7951 O O     . PRO B 2 254 ? 192.593 212.012 189.547 1.00 38.84  ? 258 PRO F O     1 
ATOM   7952 C CB    . PRO B 2 254 ? 190.521 212.568 191.726 1.00 38.84  ? 258 PRO F CB    1 
ATOM   7953 C CG    . PRO B 2 254 ? 190.655 213.774 192.489 1.00 38.84  ? 258 PRO F CG    1 
ATOM   7954 C CD    . PRO B 2 254 ? 191.540 213.468 193.643 1.00 38.84  ? 258 PRO F CD    1 
ATOM   7955 N N     . GLU B 2 255 ? 193.750 213.311 190.962 1.00 39.81  ? 259 GLU F N     1 
ATOM   7956 C CA    . GLU B 2 255 ? 194.749 213.672 189.971 1.00 39.81  ? 259 GLU F CA    1 
ATOM   7957 C C     . GLU B 2 255 ? 195.625 212.489 189.588 1.00 39.81  ? 259 GLU F C     1 
ATOM   7958 O O     . GLU B 2 255 ? 196.303 212.532 188.559 1.00 39.81  ? 259 GLU F O     1 
ATOM   7959 C CB    . GLU B 2 255 ? 195.593 214.814 190.517 1.00 39.81  ? 259 GLU F CB    1 
ATOM   7960 C CG    . GLU B 2 255 ? 196.771 215.187 189.687 1.00 39.81  ? 259 GLU F CG    1 
ATOM   7961 C CD    . GLU B 2 255 ? 196.377 215.844 188.406 1.00 39.81  ? 259 GLU F CD    1 
ATOM   7962 O OE1   . GLU B 2 255 ? 195.249 216.364 188.332 1.00 39.81  ? 259 GLU F OE1   1 
ATOM   7963 O OE2   . GLU B 2 255 ? 197.199 215.848 187.469 1.00 39.81  ? 259 GLU F OE2   1 
ATOM   7964 N N     . THR B 2 256 ? 195.630 211.431 190.388 1.00 36.93  ? 260 THR F N     1 
ATOM   7965 C CA    . THR B 2 256 ? 196.337 210.224 190.001 1.00 36.93  ? 260 THR F CA    1 
ATOM   7966 C C     . THR B 2 256 ? 195.776 209.625 188.727 1.00 36.93  ? 260 THR F C     1 
ATOM   7967 O O     . THR B 2 256 ? 196.494 208.915 188.023 1.00 36.93  ? 260 THR F O     1 
ATOM   7968 C CB    . THR B 2 256 ? 196.262 209.208 191.125 1.00 36.93  ? 260 THR F CB    1 
ATOM   7969 O OG1   . THR B 2 256 ? 196.555 209.865 192.355 1.00 36.93  ? 260 THR F OG1   1 
ATOM   7970 C CG2   . THR B 2 256 ? 197.256 208.113 190.913 1.00 36.93  ? 260 THR F CG2   1 
ATOM   7971 N N     . LEU B 2 257 ? 194.512 209.892 188.410 1.00 35.77  ? 261 LEU F N     1 
ATOM   7972 C CA    . LEU B 2 257 ? 193.951 209.380 187.169 1.00 35.77  ? 261 LEU F CA    1 
ATOM   7973 C C     . LEU B 2 257 ? 194.600 210.028 185.963 1.00 35.77  ? 261 LEU F C     1 
ATOM   7974 O O     . LEU B 2 257 ? 194.702 209.404 184.908 1.00 35.77  ? 261 LEU F O     1 
ATOM   7975 C CB    . LEU B 2 257 ? 192.447 209.608 187.136 1.00 35.77  ? 261 LEU F CB    1 
ATOM   7976 C CG    . LEU B 2 257 ? 191.606 208.706 188.018 1.00 35.77  ? 261 LEU F CG    1 
ATOM   7977 C CD1   . LEU B 2 257 ? 190.182 209.134 187.937 1.00 35.77  ? 261 LEU F CD1   1 
ATOM   7978 C CD2   . LEU B 2 257 ? 191.739 207.281 187.586 1.00 35.77  ? 261 LEU F CD2   1 
ATOM   7979 N N     . PHE B 2 258 ? 195.040 211.267 186.095 1.00 36.90  ? 262 PHE F N     1 
ATOM   7980 C CA    . PHE B 2 258 ? 195.655 211.984 184.998 1.00 36.90  ? 262 PHE F CA    1 
ATOM   7981 C C     . PHE B 2 258 ? 197.167 211.980 185.068 1.00 36.90  ? 262 PHE F C     1 
ATOM   7982 O O     . PHE B 2 258 ? 197.813 212.362 184.093 1.00 36.90  ? 262 PHE F O     1 
ATOM   7983 C CB    . PHE B 2 258 ? 195.146 213.423 184.967 1.00 36.90  ? 262 PHE F CB    1 
ATOM   7984 C CG    . PHE B 2 258 ? 193.667 213.527 184.815 1.00 36.90  ? 262 PHE F CG    1 
ATOM   7985 C CD1   . PHE B 2 258 ? 193.098 213.651 183.570 1.00 36.90  ? 262 PHE F CD1   1 
ATOM   7986 C CD2   . PHE B 2 258 ? 192.845 213.485 185.913 1.00 36.90  ? 262 PHE F CD2   1 
ATOM   7987 C CE1   . PHE B 2 258 ? 191.743 213.735 183.429 1.00 36.90  ? 262 PHE F CE1   1 
ATOM   7988 C CE2   . PHE B 2 258 ? 191.490 213.566 185.774 1.00 36.90  ? 262 PHE F CE2   1 
ATOM   7989 C CZ    . PHE B 2 258 ? 190.939 213.693 184.533 1.00 36.90  ? 262 PHE F CZ    1 
ATOM   7990 N N     . GLN B 2 259 ? 197.743 211.587 186.196 1.00 37.68  ? 263 GLN F N     1 
ATOM   7991 C CA    . GLN B 2 259 ? 199.191 211.435 186.332 1.00 37.68  ? 263 GLN F CA    1 
ATOM   7992 C C     . GLN B 2 259 ? 199.493 210.164 187.103 1.00 37.68  ? 263 GLN F C     1 
ATOM   7993 O O     . GLN B 2 259 ? 199.927 210.210 188.255 1.00 37.68  ? 263 GLN F O     1 
ATOM   7994 C CB    . GLN B 2 259 ? 199.804 212.641 187.036 1.00 37.68  ? 263 GLN F CB    1 
ATOM   7995 C CG    . GLN B 2 259 ? 199.633 213.926 186.309 1.00 37.68  ? 263 GLN F CG    1 
ATOM   7996 C CD    . GLN B 2 259 ? 200.391 215.036 186.960 1.00 37.68  ? 263 GLN F CD    1 
ATOM   7997 O OE1   . GLN B 2 259 ? 201.423 214.809 187.579 1.00 37.68  ? 263 GLN F OE1   1 
ATOM   7998 N NE2   . GLN B 2 259 ? 199.887 216.249 186.833 1.00 37.68  ? 263 GLN F NE2   1 
ATOM   7999 N N     . PRO B 2 260 ? 199.309 209.011 186.487 1.00 35.91  ? 264 PRO F N     1 
ATOM   8000 C CA    . PRO B 2 260 ? 199.482 207.756 187.222 1.00 35.91  ? 264 PRO F CA    1 
ATOM   8001 C C     . PRO B 2 260 ? 200.907 207.496 187.675 1.00 35.91  ? 264 PRO F C     1 
ATOM   8002 O O     . PRO B 2 260 ? 201.186 206.451 188.257 1.00 35.91  ? 264 PRO F O     1 
ATOM   8003 C CB    . PRO B 2 260 ? 199.013 206.701 186.220 1.00 35.91  ? 264 PRO F CB    1 
ATOM   8004 C CG    . PRO B 2 260 ? 199.131 207.325 184.943 1.00 35.91  ? 264 PRO F CG    1 
ATOM   8005 C CD    . PRO B 2 260 ? 198.880 208.769 185.110 1.00 35.91  ? 264 PRO F CD    1 
ATOM   8006 N N     . SER B 2 261 ? 201.819 208.427 187.420 1.00 37.17  ? 265 SER F N     1 
ATOM   8007 C CA    . SER B 2 261 ? 203.134 208.334 188.026 1.00 37.17  ? 265 SER F CA    1 
ATOM   8008 C C     . SER B 2 261 ? 203.102 208.635 189.512 1.00 37.17  ? 265 SER F C     1 
ATOM   8009 O O     . SER B 2 261 ? 204.080 208.345 190.202 1.00 37.17  ? 265 SER F O     1 
ATOM   8010 C CB    . SER B 2 261 ? 204.103 209.282 187.334 1.00 37.17  ? 265 SER F CB    1 
ATOM   8011 O OG    . SER B 2 261 ? 203.771 210.625 187.601 1.00 37.17  ? 265 SER F OG    1 
ATOM   8012 N N     . PHE B 2 262 ? 202.008 209.208 190.014 1.00 35.66  ? 266 PHE F N     1 
ATOM   8013 C CA    . PHE B 2 262 ? 201.890 209.470 191.441 1.00 35.66  ? 266 PHE F CA    1 
ATOM   8014 C C     . PHE B 2 262 ? 201.944 208.182 192.241 1.00 35.66  ? 266 PHE F C     1 
ATOM   8015 O O     . PHE B 2 262 ? 202.537 208.139 193.320 1.00 35.66  ? 266 PHE F O     1 
ATOM   8016 C CB    . PHE B 2 262 ? 200.593 210.210 191.728 1.00 35.66  ? 266 PHE F CB    1 
ATOM   8017 C CG    . PHE B 2 262 ? 200.654 211.667 191.437 1.00 35.66  ? 266 PHE F CG    1 
ATOM   8018 C CD1   . PHE B 2 262 ? 201.821 212.250 191.022 1.00 35.66  ? 266 PHE F CD1   1 
ATOM   8019 C CD2   . PHE B 2 262 ? 199.535 212.456 191.583 1.00 35.66  ? 266 PHE F CD2   1 
ATOM   8020 C CE1   . PHE B 2 262 ? 201.867 213.587 190.754 1.00 35.66  ? 266 PHE F CE1   1 
ATOM   8021 C CE2   . PHE B 2 262 ? 199.584 213.789 191.317 1.00 35.66  ? 266 PHE F CE2   1 
ATOM   8022 C CZ    . PHE B 2 262 ? 200.749 214.353 190.900 1.00 35.66  ? 266 PHE F CZ    1 
ATOM   8023 N N     . ILE B 2 263 ? 201.329 207.125 191.736 1.00 35.16  ? 267 ILE F N     1 
ATOM   8024 C CA    . ILE B 2 263 ? 201.377 205.833 192.387 1.00 35.16  ? 267 ILE F CA    1 
ATOM   8025 C C     . ILE B 2 263 ? 202.385 204.908 191.710 1.00 35.16  ? 267 ILE F C     1 
ATOM   8026 O O     . ILE B 2 263 ? 202.252 203.692 191.779 1.00 35.16  ? 267 ILE F O     1 
ATOM   8027 C CB    . ILE B 2 263 ? 199.993 205.181 192.464 1.00 35.16  ? 267 ILE F CB    1 
ATOM   8028 C CG1   . ILE B 2 263 ? 199.413 204.992 191.076 1.00 35.16  ? 267 ILE F CG1   1 
ATOM   8029 C CG2   . ILE B 2 263 ? 199.076 206.029 193.259 1.00 35.16  ? 267 ILE F CG2   1 
ATOM   8030 C CD1   . ILE B 2 263 ? 198.360 203.950 191.026 1.00 35.16  ? 267 ILE F CD1   1 
ATOM   8031 N N     . GLY B 2 264 ? 203.371 205.468 191.030 1.00 37.41  ? 268 GLY F N     1 
ATOM   8032 C CA    . GLY B 2 264 ? 204.441 204.670 190.485 1.00 37.41  ? 268 GLY F CA    1 
ATOM   8033 C C     . GLY B 2 264 ? 204.089 203.836 189.282 1.00 37.41  ? 268 GLY F C     1 
ATOM   8034 O O     . GLY B 2 264 ? 204.858 202.941 188.929 1.00 37.41  ? 268 GLY F O     1 
ATOM   8035 N N     . MET B 2 265 ? 202.956 204.085 188.643 1.00 38.58  ? 269 MET F N     1 
ATOM   8036 C CA    . MET B 2 265 ? 202.672 203.443 187.375 1.00 38.58  ? 269 MET F CA    1 
ATOM   8037 C C     . MET B 2 265 ? 203.335 204.223 186.255 1.00 38.58  ? 269 MET F C     1 
ATOM   8038 O O     . MET B 2 265 ? 203.584 205.421 186.368 1.00 38.58  ? 269 MET F O     1 
ATOM   8039 C CB    . MET B 2 265 ? 201.171 203.351 187.140 1.00 38.58  ? 269 MET F CB    1 
ATOM   8040 C CG    . MET B 2 265 ? 200.514 202.285 187.963 1.00 38.58  ? 269 MET F CG    1 
ATOM   8041 S SD    . MET B 2 265 ? 198.784 202.077 187.559 1.00 38.58  ? 269 MET F SD    1 
ATOM   8042 C CE    . MET B 2 265 ? 198.914 201.539 185.864 1.00 38.58  ? 269 MET F CE    1 
ATOM   8043 N N     . GLU B 2 266 ? 203.644 203.527 185.171 1.00 42.59  ? 270 GLU F N     1 
ATOM   8044 C CA    . GLU B 2 266 ? 204.312 204.195 184.069 1.00 42.59  ? 270 GLU F CA    1 
ATOM   8045 C C     . GLU B 2 266 ? 203.333 204.717 183.030 1.00 42.59  ? 270 GLU F C     1 
ATOM   8046 O O     . GLU B 2 266 ? 203.670 205.633 182.278 1.00 42.59  ? 270 GLU F O     1 
ATOM   8047 C CB    . GLU B 2 266 ? 205.310 203.259 183.407 1.00 42.59  ? 270 GLU F CB    1 
ATOM   8048 C CG    . GLU B 2 266 ? 206.163 204.002 182.410 1.00 42.59  ? 270 GLU F CG    1 
ATOM   8049 C CD    . GLU B 2 266 ? 207.149 203.132 181.709 1.00 42.59  ? 270 GLU F CD    1 
ATOM   8050 O OE1   . GLU B 2 266 ? 207.141 201.919 181.955 1.00 42.59  ? 270 GLU F OE1   1 
ATOM   8051 O OE2   . GLU B 2 266 ? 207.935 203.674 180.907 1.00 42.59  ? 270 GLU F OE2   1 
ATOM   8052 N N     . SER B 2 267 ? 202.122 204.177 182.987 1.00 39.76  ? 271 SER F N     1 
ATOM   8053 C CA    . SER B 2 267 ? 201.222 204.433 181.878 1.00 39.76  ? 271 SER F CA    1 
ATOM   8054 C C     . SER B 2 267 ? 200.778 205.891 181.856 1.00 39.76  ? 271 SER F C     1 
ATOM   8055 O O     . SER B 2 267 ? 201.238 206.731 182.628 1.00 39.76  ? 271 SER F O     1 
ATOM   8056 C CB    . SER B 2 267 ? 200.018 203.511 181.963 1.00 39.76  ? 271 SER F CB    1 
ATOM   8057 O OG    . SER B 2 267 ? 199.528 203.458 183.283 1.00 39.76  ? 271 SER F OG    1 
ATOM   8058 N N     . ALA B 2 268 ? 199.883 206.196 180.934 1.00 37.63  ? 272 ALA F N     1 
ATOM   8059 C CA    . ALA B 2 268 ? 199.429 207.554 180.710 1.00 37.63  ? 272 ALA F CA    1 
ATOM   8060 C C     . ALA B 2 268 ? 198.045 207.744 181.306 1.00 37.63  ? 272 ALA F C     1 
ATOM   8061 O O     . ALA B 2 268 ? 197.327 206.787 181.590 1.00 37.63  ? 272 ALA F O     1 
ATOM   8062 C CB    . ALA B 2 268 ? 199.419 207.875 179.215 1.00 37.63  ? 272 ALA F CB    1 
ATOM   8063 N N     . GLY B 2 269 ? 197.674 209.002 181.486 1.00 34.84  ? 273 GLY F N     1 
ATOM   8064 C CA    . GLY B 2 269 ? 196.401 209.320 182.090 1.00 34.84  ? 273 GLY F CA    1 
ATOM   8065 C C     . GLY B 2 269 ? 195.239 208.814 181.273 1.00 34.84  ? 273 GLY F C     1 
ATOM   8066 O O     . GLY B 2 269 ? 195.377 208.300 180.168 1.00 34.84  ? 273 GLY F O     1 
ATOM   8067 N N     . ILE B 2 270 ? 194.049 208.959 181.846 1.00 34.54  ? 274 ILE F N     1 
ATOM   8068 C CA    . ILE B 2 270 ? 192.861 208.533 181.128 1.00 34.54  ? 274 ILE F CA    1 
ATOM   8069 C C     . ILE B 2 270 ? 192.620 209.427 179.927 1.00 34.54  ? 274 ILE F C     1 
ATOM   8070 O O     . ILE B 2 270 ? 192.171 208.958 178.875 1.00 34.54  ? 274 ILE F O     1 
ATOM   8071 C CB    . ILE B 2 270 ? 191.656 208.506 182.075 1.00 34.54  ? 274 ILE F CB    1 
ATOM   8072 C CG1   . ILE B 2 270 ? 191.512 209.834 182.795 1.00 34.54  ? 274 ILE F CG1   1 
ATOM   8073 C CG2   . ILE B 2 270 ? 191.821 207.417 183.083 1.00 34.54  ? 274 ILE F CG2   1 
ATOM   8074 C CD1   . ILE B 2 270 ? 190.226 209.957 183.525 1.00 34.54  ? 274 ILE F CD1   1 
ATOM   8075 N N     . HIS B 2 271 ? 192.948 210.713 180.042 1.00 37.08  ? 275 HIS F N     1 
ATOM   8076 C CA    . HIS B 2 271 ? 192.786 211.625 178.919 1.00 37.08  ? 275 HIS F CA    1 
ATOM   8077 C C     . HIS B 2 271 ? 193.681 211.243 177.763 1.00 37.08  ? 275 HIS F C     1 
ATOM   8078 O O     . HIS B 2 271 ? 193.385 211.574 176.614 1.00 37.08  ? 275 HIS F O     1 
ATOM   8079 C CB    . HIS B 2 271 ? 193.096 213.050 179.348 1.00 37.08  ? 275 HIS F CB    1 
ATOM   8080 C CG    . HIS B 2 271 ? 194.542 213.289 179.637 1.00 37.08  ? 275 HIS F CG    1 
ATOM   8081 N ND1   . HIS B 2 271 ? 195.220 212.620 180.628 1.00 37.08  ? 275 HIS F ND1   1 
ATOM   8082 C CD2   . HIS B 2 271 ? 195.438 214.128 179.072 1.00 37.08  ? 275 HIS F CD2   1 
ATOM   8083 C CE1   . HIS B 2 271 ? 196.471 213.035 180.661 1.00 37.08  ? 275 HIS F CE1   1 
ATOM   8084 N NE2   . HIS B 2 271 ? 196.630 213.949 179.725 1.00 37.08  ? 275 HIS F NE2   1 
ATOM   8085 N N     . GLU B 2 272 ? 194.779 210.564 178.042 1.00 37.47  ? 276 GLU F N     1 
ATOM   8086 C CA    . GLU B 2 272 ? 195.719 210.198 177.002 1.00 37.47  ? 276 GLU F CA    1 
ATOM   8087 C C     . GLU B 2 272 ? 195.467 208.806 176.461 1.00 37.47  ? 276 GLU F C     1 
ATOM   8088 O O     . GLU B 2 272 ? 195.654 208.581 175.266 1.00 37.47  ? 276 GLU F O     1 
ATOM   8089 C CB    . GLU B 2 272 ? 197.139 210.309 177.536 1.00 37.47  ? 276 GLU F CB    1 
ATOM   8090 C CG    . GLU B 2 272 ? 198.194 210.178 176.496 1.00 37.47  ? 276 GLU F CG    1 
ATOM   8091 C CD    . GLU B 2 272 ? 199.485 210.822 176.926 1.00 37.47  ? 276 GLU F CD    1 
ATOM   8092 O OE1   . GLU B 2 272 ? 199.421 211.854 177.624 1.00 37.47  ? 276 GLU F OE1   1 
ATOM   8093 O OE2   . GLU B 2 272 ? 200.563 210.298 176.577 1.00 37.47  ? 276 GLU F OE2   1 
ATOM   8094 N N     . THR B 2 273 ? 195.014 207.866 177.283 1.00 34.97  ? 277 THR F N     1 
ATOM   8095 C CA    . THR B 2 273 ? 194.624 206.592 176.697 1.00 34.97  ? 277 THR F CA    1 
ATOM   8096 C C     . THR B 2 273 ? 193.362 206.727 175.862 1.00 34.97  ? 277 THR F C     1 
ATOM   8097 O O     . THR B 2 273 ? 193.211 206.015 174.869 1.00 34.97  ? 277 THR F O     1 
ATOM   8098 C CB    . THR B 2 273 ? 194.433 205.517 177.759 1.00 34.97  ? 277 THR F CB    1 
ATOM   8099 O OG1   . THR B 2 273 ? 193.277 205.807 178.540 1.00 34.97  ? 277 THR F OG1   1 
ATOM   8100 C CG2   . THR B 2 273 ? 195.637 205.441 178.647 1.00 34.97  ? 277 THR F CG2   1 
ATOM   8101 N N     . THR B 2 274 ? 192.458 207.643 176.215 1.00 34.72  ? 278 THR F N     1 
ATOM   8102 C CA    . THR B 2 274 ? 191.299 207.888 175.362 1.00 34.72  ? 278 THR F CA    1 
ATOM   8103 C C     . THR B 2 274 ? 191.730 208.375 173.988 1.00 34.72  ? 278 THR F C     1 
ATOM   8104 O O     . THR B 2 274 ? 191.288 207.854 172.956 1.00 34.72  ? 278 THR F O     1 
ATOM   8105 C CB    . THR B 2 274 ? 190.376 208.905 176.025 1.00 34.72  ? 278 THR F CB    1 
ATOM   8106 O OG1   . THR B 2 274 ? 189.808 208.330 177.202 1.00 34.72  ? 278 THR F OG1   1 
ATOM   8107 C CG2   . THR B 2 274 ? 189.266 209.291 175.104 1.00 34.72  ? 278 THR F CG2   1 
ATOM   8108 N N     . TYR B 2 275 ? 192.610 209.369 173.960 1.00 36.27  ? 279 TYR F N     1 
ATOM   8109 C CA    . TYR B 2 275 ? 193.103 209.896 172.699 1.00 36.27  ? 279 TYR F CA    1 
ATOM   8110 C C     . TYR B 2 275 ? 193.874 208.846 171.916 1.00 36.27  ? 279 TYR F C     1 
ATOM   8111 O O     . TYR B 2 275 ? 193.785 208.796 170.689 1.00 36.27  ? 279 TYR F O     1 
ATOM   8112 C CB    . TYR B 2 275 ? 193.971 211.114 172.967 1.00 36.27  ? 279 TYR F CB    1 
ATOM   8113 C CG    . TYR B 2 275 ? 194.677 211.643 171.762 1.00 36.27  ? 279 TYR F CG    1 
ATOM   8114 C CD1   . TYR B 2 275 ? 193.992 212.327 170.786 1.00 36.27  ? 279 TYR F CD1   1 
ATOM   8115 C CD2   . TYR B 2 275 ? 196.033 211.479 171.612 1.00 36.27  ? 279 TYR F CD2   1 
ATOM   8116 C CE1   . TYR B 2 275 ? 194.636 212.813 169.691 1.00 36.27  ? 279 TYR F CE1   1 
ATOM   8117 C CE2   . TYR B 2 275 ? 196.684 211.965 170.521 1.00 36.27  ? 279 TYR F CE2   1 
ATOM   8118 C CZ    . TYR B 2 275 ? 195.982 212.630 169.563 1.00 36.27  ? 279 TYR F CZ    1 
ATOM   8119 O OH    . TYR B 2 275 ? 196.638 213.119 168.464 1.00 36.27  ? 279 TYR F OH    1 
ATOM   8120 N N     . ASN B 2 276 ? 194.628 207.987 172.597 1.00 35.49  ? 280 ASN F N     1 
ATOM   8121 C CA    . ASN B 2 276 ? 195.375 206.963 171.879 1.00 35.49  ? 280 ASN F CA    1 
ATOM   8122 C C     . ASN B 2 276 ? 194.455 205.914 171.282 1.00 35.49  ? 280 ASN F C     1 
ATOM   8123 O O     . ASN B 2 276 ? 194.717 205.407 170.189 1.00 35.49  ? 280 ASN F O     1 
ATOM   8124 C CB    . ASN B 2 276 ? 196.394 206.311 172.797 1.00 35.49  ? 280 ASN F CB    1 
ATOM   8125 C CG    . ASN B 2 276 ? 197.590 207.177 173.026 1.00 35.49  ? 280 ASN F CG    1 
ATOM   8126 O OD1   . ASN B 2 276 ? 197.843 208.106 172.271 1.00 35.49  ? 280 ASN F OD1   1 
ATOM   8127 N ND2   . ASN B 2 276 ? 198.340 206.882 174.069 1.00 35.49  ? 280 ASN F ND2   1 
ATOM   8128 N N     . SER B 2 277 ? 193.374 205.572 171.971 1.00 33.98  ? 281 SER F N     1 
ATOM   8129 C CA    . SER B 2 277 ? 192.408 204.661 171.374 1.00 33.98  ? 281 SER F CA    1 
ATOM   8130 C C     . SER B 2 277 ? 191.766 205.283 170.143 1.00 33.98  ? 281 SER F C     1 
ATOM   8131 O O     . SER B 2 277 ? 191.609 204.625 169.103 1.00 33.98  ? 281 SER F O     1 
ATOM   8132 C CB    . SER B 2 277 ? 191.357 204.286 172.404 1.00 33.98  ? 281 SER F CB    1 
ATOM   8133 O OG    . SER B 2 277 ? 190.470 203.332 171.880 1.00 33.98  ? 281 SER F OG    1 
ATOM   8134 N N     . ILE B 2 278 ? 191.423 206.566 170.227 1.00 35.12  ? 282 ILE F N     1 
ATOM   8135 C CA    . ILE B 2 278 ? 190.876 207.251 169.061 1.00 35.12  ? 282 ILE F CA    1 
ATOM   8136 C C     . ILE B 2 278 ? 191.867 207.207 167.905 1.00 35.12  ? 282 ILE F C     1 
ATOM   8137 O O     . ILE B 2 278 ? 191.508 206.868 166.776 1.00 35.12  ? 282 ILE F O     1 
ATOM   8138 C CB    . ILE B 2 278 ? 190.480 208.689 169.420 1.00 35.12  ? 282 ILE F CB    1 
ATOM   8139 C CG1   . ILE B 2 278 ? 189.268 208.680 170.336 1.00 35.12  ? 282 ILE F CG1   1 
ATOM   8140 C CG2   . ILE B 2 278 ? 190.140 209.446 168.192 1.00 35.12  ? 282 ILE F CG2   1 
ATOM   8141 C CD1   . ILE B 2 278 ? 188.921 210.024 170.894 1.00 35.12  ? 282 ILE F CD1   1 
ATOM   8142 N N     . MET B 2 279 ? 193.134 207.509 168.170 1.00 35.92  ? 283 MET F N     1 
ATOM   8143 C CA    . MET B 2 279 ? 194.115 207.517 167.092 1.00 35.92  ? 283 MET F CA    1 
ATOM   8144 C C     . MET B 2 279 ? 194.440 206.127 166.579 1.00 35.92  ? 283 MET F C     1 
ATOM   8145 O O     . MET B 2 279 ? 195.018 206.007 165.498 1.00 35.92  ? 283 MET F O     1 
ATOM   8146 C CB    . MET B 2 279 ? 195.401 208.201 167.531 1.00 35.92  ? 283 MET F CB    1 
ATOM   8147 C CG    . MET B 2 279 ? 195.211 209.637 167.895 1.00 35.92  ? 283 MET F CG    1 
ATOM   8148 S SD    . MET B 2 279 ? 194.206 210.527 166.709 1.00 35.92  ? 283 MET F SD    1 
ATOM   8149 C CE    . MET B 2 279 ? 195.399 210.823 165.419 1.00 35.92  ? 283 MET F CE    1 
ATOM   8150 N N     . LYS B 2 280 ? 194.134 205.078 167.332 1.00 34.98  ? 284 LYS F N     1 
ATOM   8151 C CA    . LYS B 2 280 ? 194.217 203.745 166.749 1.00 34.98  ? 284 LYS F CA    1 
ATOM   8152 C C     . LYS B 2 280 ? 193.054 203.489 165.813 1.00 34.98  ? 284 LYS F C     1 
ATOM   8153 O O     . LYS B 2 280 ? 193.172 202.700 164.874 1.00 34.98  ? 284 LYS F O     1 
ATOM   8154 C CB    . LYS B 2 280 ? 194.249 202.675 167.828 1.00 34.98  ? 284 LYS F CB    1 
ATOM   8155 C CG    . LYS B 2 280 ? 195.515 202.627 168.607 1.00 34.98  ? 284 LYS F CG    1 
ATOM   8156 C CD    . LYS B 2 280 ? 195.462 201.507 169.601 1.00 34.98  ? 284 LYS F CD    1 
ATOM   8157 C CE    . LYS B 2 280 ? 196.684 201.520 170.475 1.00 34.98  ? 284 LYS F CE    1 
ATOM   8158 N NZ    . LYS B 2 280 ? 197.889 201.204 169.677 1.00 34.98  ? 284 LYS F NZ    1 
ATOM   8159 N N     . CYS B 2 281 ? 191.912 204.112 166.073 1.00 38.12  ? 285 CYS F N     1 
ATOM   8160 C CA    . CYS B 2 281 ? 190.761 203.857 165.219 1.00 38.12  ? 285 CYS F CA    1 
ATOM   8161 C C     . CYS B 2 281 ? 190.956 204.466 163.826 1.00 38.12  ? 285 CYS F C     1 
ATOM   8162 O O     . CYS B 2 281 ? 191.794 205.341 163.608 1.00 38.12  ? 285 CYS F O     1 
ATOM   8163 C CB    . CYS B 2 281 ? 189.493 204.394 165.866 1.00 38.12  ? 285 CYS F CB    1 
ATOM   8164 S SG    . CYS B 2 281 ? 188.947 203.387 167.218 1.00 38.12  ? 285 CYS F SG    1 
ATOM   8165 N N     . ASP B 2 282 ? 190.150 203.993 162.878 1.00 43.51  ? 286 ASP F N     1 
ATOM   8166 C CA    . ASP B 2 282 ? 190.260 204.413 161.486 1.00 43.51  ? 286 ASP F CA    1 
ATOM   8167 C C     . ASP B 2 282 ? 189.967 205.896 161.333 1.00 43.51  ? 286 ASP F C     1 
ATOM   8168 O O     . ASP B 2 282 ? 189.171 206.469 162.073 1.00 43.51  ? 286 ASP F O     1 
ATOM   8169 C CB    . ASP B 2 282 ? 189.298 203.618 160.618 1.00 43.51  ? 286 ASP F CB    1 
ATOM   8170 C CG    . ASP B 2 282 ? 189.548 202.133 160.690 1.00 43.51  ? 286 ASP F CG    1 
ATOM   8171 O OD1   . ASP B 2 282 ? 190.695 201.716 160.430 1.00 43.51  ? 286 ASP F OD1   1 
ATOM   8172 O OD2   . ASP B 2 282 ? 188.606 201.381 161.019 1.00 43.51  ? 286 ASP F OD2   1 
ATOM   8173 N N     . ILE B 2 283 ? 190.593 206.514 160.331 1.00 42.96  ? 287 ILE F N     1 
ATOM   8174 C CA    . ILE B 2 283 ? 190.579 207.968 160.242 1.00 42.96  ? 287 ILE F CA    1 
ATOM   8175 C C     . ILE B 2 283 ? 189.198 208.519 159.935 1.00 42.96  ? 287 ILE F C     1 
ATOM   8176 O O     . ILE B 2 283 ? 188.928 209.692 160.203 1.00 42.96  ? 287 ILE F O     1 
ATOM   8177 C CB    . ILE B 2 283 ? 191.593 208.440 159.193 1.00 42.96  ? 287 ILE F CB    1 
ATOM   8178 C CG1   . ILE B 2 283 ? 191.729 209.955 159.226 1.00 42.96  ? 287 ILE F CG1   1 
ATOM   8179 C CG2   . ILE B 2 283 ? 191.168 207.996 157.835 1.00 42.96  ? 287 ILE F CG2   1 
ATOM   8180 C CD1   . ILE B 2 283 ? 192.796 210.472 158.346 1.00 42.96  ? 287 ILE F CD1   1 
ATOM   8181 N N     . ASP B 2 284 ? 188.299 207.708 159.405 1.00 45.26  ? 288 ASP F N     1 
ATOM   8182 C CA    . ASP B 2 284 ? 187.008 208.227 158.996 1.00 45.26  ? 288 ASP F CA    1 
ATOM   8183 C C     . ASP B 2 284 ? 186.019 208.340 160.141 1.00 45.26  ? 288 ASP F C     1 
ATOM   8184 O O     . ASP B 2 284 ? 185.010 209.032 159.991 1.00 45.26  ? 288 ASP F O     1 
ATOM   8185 C CB    . ASP B 2 284 ? 186.431 207.339 157.904 1.00 45.26  ? 288 ASP F CB    1 
ATOM   8186 C CG    . ASP B 2 284 ? 187.484 206.889 156.916 1.00 45.26  ? 288 ASP F CG    1 
ATOM   8187 O OD1   . ASP B 2 284 ? 187.960 207.728 156.128 1.00 45.26  ? 288 ASP F OD1   1 
ATOM   8188 O OD2   . ASP B 2 284 ? 187.855 205.699 156.938 1.00 45.26  ? 288 ASP F OD2   1 
ATOM   8189 N N     . ILE B 2 285 ? 186.276 207.698 161.278 1.00 40.43  ? 289 ILE F N     1 
ATOM   8190 C CA    . ILE B 2 285 ? 185.342 207.706 162.395 1.00 40.43  ? 289 ILE F CA    1 
ATOM   8191 C C     . ILE B 2 285 ? 185.846 208.514 163.572 1.00 40.43  ? 289 ILE F C     1 
ATOM   8192 O O     . ILE B 2 285 ? 185.145 208.610 164.591 1.00 40.43  ? 289 ILE F O     1 
ATOM   8193 C CB    . ILE B 2 285 ? 184.996 206.276 162.832 1.00 40.43  ? 289 ILE F CB    1 
ATOM   8194 C CG1   . ILE B 2 285 ? 186.212 205.582 163.410 1.00 40.43  ? 289 ILE F CG1   1 
ATOM   8195 C CG2   . ILE B 2 285 ? 184.524 205.483 161.659 1.00 40.43  ? 289 ILE F CG2   1 
ATOM   8196 C CD1   . ILE B 2 285 ? 185.938 204.182 163.807 1.00 40.43  ? 289 ILE F CD1   1 
ATOM   8197 N N     . ARG B 2 286 ? 187.021 209.123 163.463 1.00 38.66  ? 290 ARG F N     1 
ATOM   8198 C CA    . ARG B 2 286 ? 187.575 209.840 164.598 1.00 38.66  ? 290 ARG F CA    1 
ATOM   8199 C C     . ARG B 2 286 ? 186.766 211.075 164.949 1.00 38.66  ? 290 ARG F C     1 
ATOM   8200 O O     . ARG B 2 286 ? 186.711 211.452 166.119 1.00 38.66  ? 290 ARG F O     1 
ATOM   8201 C CB    . ARG B 2 286 ? 189.018 210.219 164.323 1.00 38.66  ? 290 ARG F CB    1 
ATOM   8202 C CG    . ARG B 2 286 ? 189.934 209.051 164.339 1.00 38.66  ? 290 ARG F CG    1 
ATOM   8203 C CD    . ARG B 2 286 ? 191.306 209.446 163.932 1.00 38.66  ? 290 ARG F CD    1 
ATOM   8204 N NE    . ARG B 2 286 ? 192.068 208.288 163.514 1.00 38.66  ? 290 ARG F NE    1 
ATOM   8205 C CZ    . ARG B 2 286 ? 193.244 208.359 162.919 1.00 38.66  ? 290 ARG F CZ    1 
ATOM   8206 N NH1   . ARG B 2 286 ? 193.788 209.533 162.681 1.00 38.66  ? 290 ARG F NH1   1 
ATOM   8207 N NH2   . ARG B 2 286 ? 193.876 207.258 162.569 1.00 38.66  ? 290 ARG F NH2   1 
ATOM   8208 N N     . LYS B 2 287 ? 186.130 211.717 163.974 1.00 40.72  ? 291 LYS F N     1 
ATOM   8209 C CA    . LYS B 2 287 ? 185.313 212.883 164.289 1.00 40.72  ? 291 LYS F CA    1 
ATOM   8210 C C     . LYS B 2 287 ? 184.117 212.496 165.145 1.00 40.72  ? 291 LYS F C     1 
ATOM   8211 O O     . LYS B 2 287 ? 183.819 213.150 166.154 1.00 40.72  ? 291 LYS F O     1 
ATOM   8212 C CB    . LYS B 2 287 ? 184.856 213.562 163.007 1.00 40.72  ? 291 LYS F CB    1 
ATOM   8213 C CG    . LYS B 2 287 ? 183.881 214.692 163.237 1.00 40.72  ? 291 LYS F CG    1 
ATOM   8214 C CD    . LYS B 2 287 ? 183.328 215.221 161.931 1.00 40.72  ? 291 LYS F CD    1 
ATOM   8215 C CE    . LYS B 2 287 ? 184.412 215.905 161.139 1.00 40.72  ? 291 LYS F CE    1 
ATOM   8216 N NZ    . LYS B 2 287 ? 184.260 215.707 159.670 1.00 40.72  ? 291 LYS F NZ    1 
ATOM   8217 N N     . ASP B 2 288 ? 183.424 211.426 164.764 1.00 39.99  ? 292 ASP F N     1 
ATOM   8218 C CA    . ASP B 2 288 ? 182.302 210.958 165.564 1.00 39.99  ? 292 ASP F CA    1 
ATOM   8219 C C     . ASP B 2 288 ? 182.753 210.531 166.950 1.00 39.99  ? 292 ASP F C     1 
ATOM   8220 O O     . ASP B 2 288 ? 182.073 210.809 167.947 1.00 39.99  ? 292 ASP F O     1 
ATOM   8221 C CB    . ASP B 2 288 ? 181.602 209.808 164.858 1.00 39.99  ? 292 ASP F CB    1 
ATOM   8222 C CG    . ASP B 2 288 ? 180.533 210.281 163.911 1.00 39.99  ? 292 ASP F CG    1 
ATOM   8223 O OD1   . ASP B 2 288 ? 180.533 211.478 163.573 1.00 39.99  ? 292 ASP F OD1   1 
ATOM   8224 O OD2   . ASP B 2 288 ? 179.680 209.463 163.513 1.00 39.99  ? 292 ASP F OD2   1 
ATOM   8225 N N     . LEU B 2 289 ? 183.898 209.860 167.042 1.00 36.02  ? 293 LEU F N     1 
ATOM   8226 C CA    . LEU B 2 289 ? 184.380 209.467 168.358 1.00 36.02  ? 293 LEU F CA    1 
ATOM   8227 C C     . LEU B 2 289 ? 184.691 210.684 169.215 1.00 36.02  ? 293 LEU F C     1 
ATOM   8228 O O     . LEU B 2 289 ? 184.317 210.729 170.387 1.00 36.02  ? 293 LEU F O     1 
ATOM   8229 C CB    . LEU B 2 289 ? 185.601 208.571 168.230 1.00 36.02  ? 293 LEU F CB    1 
ATOM   8230 C CG    . LEU B 2 289 ? 185.356 207.241 167.535 1.00 36.02  ? 293 LEU F CG    1 
ATOM   8231 C CD1   . LEU B 2 289 ? 186.545 206.363 167.715 1.00 36.02  ? 293 LEU F CD1   1 
ATOM   8232 C CD2   . LEU B 2 289 ? 184.133 206.571 168.061 1.00 36.02  ? 293 LEU F CD2   1 
ATOM   8233 N N     . TYR B 2 290 ? 185.360 211.687 168.649 1.00 37.15  ? 294 TYR F N     1 
ATOM   8234 C CA    . TYR B 2 290 ? 185.597 212.921 169.388 1.00 37.15  ? 294 TYR F CA    1 
ATOM   8235 C C     . TYR B 2 290 ? 184.295 213.529 169.872 1.00 37.15  ? 294 TYR F C     1 
ATOM   8236 O O     . TYR B 2 290 ? 184.246 214.140 170.940 1.00 37.15  ? 294 TYR F O     1 
ATOM   8237 C CB    . TYR B 2 290 ? 186.328 213.931 168.518 1.00 37.15  ? 294 TYR F CB    1 
ATOM   8238 C CG    . TYR B 2 290 ? 187.790 213.671 168.352 1.00 37.15  ? 294 TYR F CG    1 
ATOM   8239 C CD1   . TYR B 2 290 ? 188.569 213.311 169.420 1.00 37.15  ? 294 TYR F CD1   1 
ATOM   8240 C CD2   . TYR B 2 290 ? 188.393 213.799 167.119 1.00 37.15  ? 294 TYR F CD2   1 
ATOM   8241 C CE1   . TYR B 2 290 ? 189.899 213.083 169.267 1.00 37.15  ? 294 TYR F CE1   1 
ATOM   8242 C CE2   . TYR B 2 290 ? 189.716 213.569 166.959 1.00 37.15  ? 294 TYR F CE2   1 
ATOM   8243 C CZ    . TYR B 2 290 ? 190.465 213.213 168.036 1.00 37.15  ? 294 TYR F CZ    1 
ATOM   8244 O OH    . TYR B 2 290 ? 191.802 212.980 167.879 1.00 37.15  ? 294 TYR F OH    1 
ATOM   8245 N N     . ALA B 2 291 ? 183.235 213.398 169.091 1.00 37.28  ? 295 ALA F N     1 
ATOM   8246 C CA    . ALA B 2 291 ? 181.982 214.018 169.483 1.00 37.28  ? 295 ALA F CA    1 
ATOM   8247 C C     . ALA B 2 291 ? 181.153 213.178 170.441 1.00 37.28  ? 295 ALA F C     1 
ATOM   8248 O O     . ALA B 2 291 ? 180.172 213.689 170.980 1.00 37.28  ? 295 ALA F O     1 
ATOM   8249 C CB    . ALA B 2 291 ? 181.149 214.330 168.248 1.00 37.28  ? 295 ALA F CB    1 
ATOM   8250 N N     . ASN B 2 292 ? 181.491 211.913 170.665 1.00 37.59  ? 296 ASN F N     1 
ATOM   8251 C CA    . ASN B 2 292 ? 180.633 211.029 171.455 1.00 37.59  ? 296 ASN F CA    1 
ATOM   8252 C C     . ASN B 2 292 ? 181.403 210.338 172.562 1.00 37.59  ? 296 ASN F C     1 
ATOM   8253 O O     . ASN B 2 292 ? 181.342 209.122 172.723 1.00 37.59  ? 296 ASN F O     1 
ATOM   8254 C CB    . ASN B 2 292 ? 179.966 209.990 170.580 1.00 37.59  ? 296 ASN F CB    1 
ATOM   8255 C CG    . ASN B 2 292 ? 178.819 210.547 169.829 1.00 37.59  ? 296 ASN F CG    1 
ATOM   8256 O OD1   . ASN B 2 292 ? 178.822 211.715 169.472 1.00 37.59  ? 296 ASN F OD1   1 
ATOM   8257 N ND2   . ASN B 2 292 ? 177.810 209.727 169.590 1.00 37.59  ? 296 ASN F ND2   1 
ATOM   8258 N N     . ASN B 2 293 ? 182.135 211.101 173.353 1.00 36.67  ? 297 ASN F N     1 
ATOM   8259 C CA    . ASN B 2 293 ? 183.002 210.531 174.375 1.00 36.67  ? 297 ASN F CA    1 
ATOM   8260 C C     . ASN B 2 293 ? 182.223 210.319 175.672 1.00 36.67  ? 297 ASN F C     1 
ATOM   8261 O O     . ASN B 2 293 ? 181.954 211.272 176.402 1.00 36.67  ? 297 ASN F O     1 
ATOM   8262 C CB    . ASN B 2 293 ? 184.192 211.457 174.563 1.00 36.67  ? 297 ASN F CB    1 
ATOM   8263 C CG    . ASN B 2 293 ? 185.287 210.826 175.338 1.00 36.67  ? 297 ASN F CG    1 
ATOM   8264 O OD1   . ASN B 2 293 ? 185.133 209.738 175.884 1.00 36.67  ? 297 ASN F OD1   1 
ATOM   8265 N ND2   . ASN B 2 293 ? 186.431 211.477 175.359 1.00 36.67  ? 297 ASN F ND2   1 
ATOM   8266 N N     . VAL B 2 294 ? 181.898 209.065 175.983 1.00 33.90  ? 298 VAL F N     1 
ATOM   8267 C CA    . VAL B 2 294 ? 180.931 208.712 177.021 1.00 33.90  ? 298 VAL F CA    1 
ATOM   8268 C C     . VAL B 2 294 ? 181.657 208.257 178.280 1.00 33.90  ? 298 VAL F C     1 
ATOM   8269 O O     . VAL B 2 294 ? 182.557 207.418 178.211 1.00 33.90  ? 298 VAL F O     1 
ATOM   8270 C CB    . VAL B 2 294 ? 179.985 207.608 176.524 1.00 33.90  ? 298 VAL F CB    1 
ATOM   8271 C CG1   . VAL B 2 294 ? 179.082 207.147 177.619 1.00 33.90  ? 298 VAL F CG1   1 
ATOM   8272 C CG2   . VAL B 2 294 ? 179.177 208.101 175.365 1.00 33.90  ? 298 VAL F CG2   1 
ATOM   8273 N N     . LEU B 2 295 ? 181.249 208.782 179.433 1.00 33.85  ? 299 LEU F N     1 
ATOM   8274 C CA    . LEU B 2 295 ? 181.804 208.400 180.725 1.00 33.85  ? 299 LEU F CA    1 
ATOM   8275 C C     . LEU B 2 295 ? 180.804 207.555 181.490 1.00 33.85  ? 299 LEU F C     1 
ATOM   8276 O O     . LEU B 2 295 ? 179.606 207.826 181.458 1.00 33.85  ? 299 LEU F O     1 
ATOM   8277 C CB    . LEU B 2 295 ? 182.148 209.620 181.571 1.00 33.85  ? 299 LEU F CB    1 
ATOM   8278 C CG    . LEU B 2 295 ? 183.149 210.631 181.041 1.00 33.85  ? 299 LEU F CG    1 
ATOM   8279 C CD1   . LEU B 2 295 ? 183.430 211.650 182.098 1.00 33.85  ? 299 LEU F CD1   1 
ATOM   8280 C CD2   . LEU B 2 295 ? 184.409 209.949 180.655 1.00 33.85  ? 299 LEU F CD2   1 
ATOM   8281 N N     . SER B 2 296 ? 181.290 206.539 182.191 1.00 34.96  ? 300 SER F N     1 
ATOM   8282 C CA    . SER B 2 296 ? 180.417 205.763 183.055 1.00 34.96  ? 300 SER F CA    1 
ATOM   8283 C C     . SER B 2 296 ? 181.247 205.131 184.158 1.00 34.96  ? 300 SER F C     1 
ATOM   8284 O O     . SER B 2 296 ? 182.470 205.070 184.082 1.00 34.96  ? 300 SER F O     1 
ATOM   8285 C CB    . SER B 2 296 ? 179.650 204.710 182.269 1.00 34.96  ? 300 SER F CB    1 
ATOM   8286 O OG    . SER B 2 296 ? 180.377 203.510 182.199 1.00 34.96  ? 300 SER F OG    1 
ATOM   8287 N N     . GLY B 2 297 ? 180.571 204.679 185.201 1.00 36.39  ? 301 GLY F N     1 
ATOM   8288 C CA    . GLY B 2 297 ? 181.238 204.042 186.312 1.00 36.39  ? 301 GLY F CA    1 
ATOM   8289 C C     . GLY B 2 297 ? 181.536 205.010 187.445 1.00 36.39  ? 301 GLY F C     1 
ATOM   8290 O O     . GLY B 2 297 ? 181.651 206.220 187.260 1.00 36.39  ? 301 GLY F O     1 
ATOM   8291 N N     . GLY B 2 298 ? 181.707 204.444 188.638 1.00 38.07  ? 302 GLY F N     1 
ATOM   8292 C CA    . GLY B 2 298 ? 181.770 205.251 189.841 1.00 38.07  ? 302 GLY F CA    1 
ATOM   8293 C C     . GLY B 2 298 ? 182.945 206.201 189.910 1.00 38.07  ? 302 GLY F C     1 
ATOM   8294 O O     . GLY B 2 298 ? 182.847 207.260 190.524 1.00 38.07  ? 302 GLY F O     1 
ATOM   8295 N N     . THR B 2 299 ? 184.068 205.845 189.305 1.00 37.94  ? 303 THR F N     1 
ATOM   8296 C CA    . THR B 2 299 ? 185.242 206.700 189.391 1.00 37.94  ? 303 THR F CA    1 
ATOM   8297 C C     . THR B 2 299 ? 185.170 207.899 188.461 1.00 37.94  ? 303 THR F C     1 
ATOM   8298 O O     . THR B 2 299 ? 185.946 208.841 188.623 1.00 37.94  ? 303 THR F O     1 
ATOM   8299 C CB    . THR B 2 299 ? 186.491 205.874 189.111 1.00 37.94  ? 303 THR F CB    1 
ATOM   8300 O OG1   . THR B 2 299 ? 186.484 204.733 189.968 1.00 37.94  ? 303 THR F OG1   1 
ATOM   8301 C CG2   . THR B 2 299 ? 187.741 206.654 189.380 1.00 37.94  ? 303 THR F CG2   1 
ATOM   8302 N N     . THR B 2 300 ? 184.251 207.911 187.512 1.00 37.96  ? 304 THR F N     1 
ATOM   8303 C CA    . THR B 2 300 ? 184.030 209.085 186.684 1.00 37.96  ? 304 THR F CA    1 
ATOM   8304 C C     . THR B 2 300 ? 183.128 210.092 187.341 1.00 37.96  ? 304 THR F C     1 
ATOM   8305 O O     . THR B 2 300 ? 182.610 210.973 186.659 1.00 37.96  ? 304 THR F O     1 
ATOM   8306 C CB    . THR B 2 300 ? 183.431 208.679 185.344 1.00 37.96  ? 304 THR F CB    1 
ATOM   8307 O OG1   . THR B 2 300 ? 182.216 207.967 185.581 1.00 37.96  ? 304 THR F OG1   1 
ATOM   8308 C CG2   . THR B 2 300 ? 184.380 207.792 184.587 1.00 37.96  ? 304 THR F CG2   1 
ATOM   8309 N N     . MET B 2 301 ? 182.920 209.990 188.647 1.00 39.74  ? 305 MET F N     1 
ATOM   8310 C CA    . MET B 2 301 ? 181.883 210.745 189.325 1.00 39.74  ? 305 MET F CA    1 
ATOM   8311 C C     . MET B 2 301 ? 182.425 211.906 190.144 1.00 39.74  ? 305 MET F C     1 
ATOM   8312 O O     . MET B 2 301 ? 181.658 212.567 190.842 1.00 39.74  ? 305 MET F O     1 
ATOM   8313 C CB    . MET B 2 301 ? 181.068 209.806 190.204 1.00 39.74  ? 305 MET F CB    1 
ATOM   8314 C CG    . MET B 2 301 ? 179.716 210.326 190.573 1.00 39.74  ? 305 MET F CG    1 
ATOM   8315 S SD    . MET B 2 301 ? 178.556 210.360 189.216 1.00 39.74  ? 305 MET F SD    1 
ATOM   8316 C CE    . MET B 2 301 ? 178.047 208.659 189.236 1.00 39.74  ? 305 MET F CE    1 
ATOM   8317 N N     . TYR B 2 302 ? 183.714 212.187 190.070 1.00 41.47  ? 306 TYR F N     1 
ATOM   8318 C CA    . TYR B 2 302 ? 184.243 213.329 190.784 1.00 41.47  ? 306 TYR F CA    1 
ATOM   8319 C C     . TYR B 2 302 ? 183.716 214.622 190.176 1.00 41.47  ? 306 TYR F C     1 
ATOM   8320 O O     . TYR B 2 302 ? 183.430 214.684 188.984 1.00 41.47  ? 306 TYR F O     1 
ATOM   8321 C CB    . TYR B 2 302 ? 185.760 213.340 190.745 1.00 41.47  ? 306 TYR F CB    1 
ATOM   8322 C CG    . TYR B 2 302 ? 186.367 212.166 191.431 1.00 41.47  ? 306 TYR F CG    1 
ATOM   8323 C CD1   . TYR B 2 302 ? 186.636 211.011 190.740 1.00 41.47  ? 306 TYR F CD1   1 
ATOM   8324 C CD2   . TYR B 2 302 ? 186.659 212.205 192.775 1.00 41.47  ? 306 TYR F CD2   1 
ATOM   8325 C CE1   . TYR B 2 302 ? 187.173 209.939 191.360 1.00 41.47  ? 306 TYR F CE1   1 
ATOM   8326 C CE2   . TYR B 2 302 ? 187.207 211.133 193.400 1.00 41.47  ? 306 TYR F CE2   1 
ATOM   8327 C CZ    . TYR B 2 302 ? 187.455 210.001 192.688 1.00 41.47  ? 306 TYR F CZ    1 
ATOM   8328 O OH    . TYR B 2 302 ? 188.000 208.911 193.305 1.00 41.47  ? 306 TYR F OH    1 
ATOM   8329 N N     . PRO B 2 303 ? 183.568 215.667 190.977 1.00 44.78  ? 307 PRO F N     1 
ATOM   8330 C CA    . PRO B 2 303 ? 183.243 216.977 190.414 1.00 44.78  ? 307 PRO F CA    1 
ATOM   8331 C C     . PRO B 2 303 ? 184.412 217.522 189.612 1.00 44.78  ? 307 PRO F C     1 
ATOM   8332 O O     . PRO B 2 303 ? 185.535 217.594 190.103 1.00 44.78  ? 307 PRO F O     1 
ATOM   8333 C CB    . PRO B 2 303 ? 182.965 217.829 191.651 1.00 44.78  ? 307 PRO F CB    1 
ATOM   8334 C CG    . PRO B 2 303 ? 182.598 216.853 192.686 1.00 44.78  ? 307 PRO F CG    1 
ATOM   8335 C CD    . PRO B 2 303 ? 183.427 215.657 192.436 1.00 44.78  ? 307 PRO F CD    1 
ATOM   8336 N N     . GLY B 2 304 ? 184.141 217.907 188.375 1.00 47.73  ? 308 GLY F N     1 
ATOM   8337 C CA    . GLY B 2 304 ? 185.137 218.538 187.544 1.00 47.73  ? 308 GLY F CA    1 
ATOM   8338 C C     . GLY B 2 304 ? 185.873 217.612 186.611 1.00 47.73  ? 308 GLY F C     1 
ATOM   8339 O O     . GLY B 2 304 ? 186.722 218.080 185.843 1.00 47.73  ? 308 GLY F O     1 
ATOM   8340 N N     . ILE B 2 305 ? 185.570 216.318 186.636 1.00 43.58  ? 309 ILE F N     1 
ATOM   8341 C CA    . ILE B 2 305 ? 186.319 215.383 185.812 1.00 43.58  ? 309 ILE F CA    1 
ATOM   8342 C C     . ILE B 2 305 ? 185.962 215.558 184.344 1.00 43.58  ? 309 ILE F C     1 
ATOM   8343 O O     . ILE B 2 305 ? 186.826 215.457 183.471 1.00 43.58  ? 309 ILE F O     1 
ATOM   8344 C CB    . ILE B 2 305 ? 186.092 213.942 186.298 1.00 43.58  ? 309 ILE F CB    1 
ATOM   8345 C CG1   . ILE B 2 305 ? 187.114 213.014 185.672 1.00 43.58  ? 309 ILE F CG1   1 
ATOM   8346 C CG2   . ILE B 2 305 ? 184.703 213.461 185.972 1.00 43.58  ? 309 ILE F CG2   1 
ATOM   8347 C CD1   . ILE B 2 305 ? 187.083 211.640 186.249 1.00 43.58  ? 309 ILE F CD1   1 
ATOM   8348 N N     . ALA B 2 306 ? 184.699 215.856 184.046 1.00 43.51  ? 310 ALA F N     1 
ATOM   8349 C CA    . ALA B 2 306 ? 184.303 216.073 182.662 1.00 43.51  ? 310 ALA F CA    1 
ATOM   8350 C C     . ALA B 2 306 ? 184.973 217.312 182.089 1.00 43.51  ? 310 ALA F C     1 
ATOM   8351 O O     . ALA B 2 306 ? 185.492 217.288 180.971 1.00 43.51  ? 310 ALA F O     1 
ATOM   8352 C CB    . ALA B 2 306 ? 182.788 216.189 182.566 1.00 43.51  ? 310 ALA F CB    1 
ATOM   8353 N N     . ASP B 2 307 ? 184.981 218.406 182.843 1.00 47.74  ? 311 ASP F N     1 
ATOM   8354 C CA    . ASP B 2 307 ? 185.629 219.613 182.357 1.00 47.74  ? 311 ASP F CA    1 
ATOM   8355 C C     . ASP B 2 307 ? 187.124 219.406 182.194 1.00 47.74  ? 311 ASP F C     1 
ATOM   8356 O O     . ASP B 2 307 ? 187.717 219.863 181.211 1.00 47.74  ? 311 ASP F O     1 
ATOM   8357 C CB    . ASP B 2 307 ? 185.350 220.772 183.303 1.00 47.74  ? 311 ASP F CB    1 
ATOM   8358 C CG    . ASP B 2 307 ? 183.868 221.013 183.501 1.00 47.74  ? 311 ASP F CG    1 
ATOM   8359 O OD1   . ASP B 2 307 ? 183.082 220.646 182.603 1.00 47.74  ? 311 ASP F OD1   1 
ATOM   8360 O OD2   . ASP B 2 307 ? 183.482 221.569 184.553 1.00 47.74  ? 311 ASP F OD2   1 
ATOM   8361 N N     . ARG B 2 308 ? 187.752 218.707 183.137 1.00 42.29  ? 312 ARG F N     1 
ATOM   8362 C CA    . ARG B 2 308 ? 189.180 218.448 183.012 1.00 42.29  ? 312 ARG F CA    1 
ATOM   8363 C C     . ARG B 2 308 ? 189.481 217.617 181.781 1.00 42.29  ? 312 ARG F C     1 
ATOM   8364 O O     . ARG B 2 308 ? 190.406 217.927 181.022 1.00 42.29  ? 312 ARG F O     1 
ATOM   8365 C CB    . ARG B 2 308 ? 189.697 217.742 184.254 1.00 42.29  ? 312 ARG F CB    1 
ATOM   8366 C CG    . ARG B 2 308 ? 191.144 217.379 184.168 1.00 42.29  ? 312 ARG F CG    1 
ATOM   8367 C CD    . ARG B 2 308 ? 192.000 218.594 184.253 1.00 42.29  ? 312 ARG F CD    1 
ATOM   8368 N NE    . ARG B 2 308 ? 193.405 218.264 184.106 1.00 42.29  ? 312 ARG F NE    1 
ATOM   8369 C CZ    . ARG B 2 308 ? 194.169 217.810 185.086 1.00 42.29  ? 312 ARG F CZ    1 
ATOM   8370 N NH1   . ARG B 2 308 ? 193.664 217.631 186.292 1.00 42.29  ? 312 ARG F NH1   1 
ATOM   8371 N NH2   . ARG B 2 308 ? 195.441 217.535 184.858 1.00 42.29  ? 312 ARG F NH2   1 
ATOM   8372 N N     . MET B 2 309 ? 188.715 216.552 181.562 1.00 41.34  ? 313 MET F N     1 
ATOM   8373 C CA    . MET B 2 309 ? 189.015 215.686 180.437 1.00 41.34  ? 313 MET F CA    1 
ATOM   8374 C C     . MET B 2 309 ? 188.731 216.374 179.122 1.00 41.34  ? 313 MET F C     1 
ATOM   8375 O O     . MET B 2 309 ? 189.433 216.131 178.140 1.00 41.34  ? 313 MET F O     1 
ATOM   8376 C CB    . MET B 2 309 ? 188.235 214.385 180.534 1.00 41.34  ? 313 MET F CB    1 
ATOM   8377 C CG    . MET B 2 309 ? 189.063 213.195 180.113 1.00 41.34  ? 313 MET F CG    1 
ATOM   8378 S SD    . MET B 2 309 ? 188.098 211.709 180.108 1.00 41.34  ? 313 MET F SD    1 
ATOM   8379 C CE    . MET B 2 309 ? 187.163 212.013 181.591 1.00 41.34  ? 313 MET F CE    1 
ATOM   8380 N N     . GLN B 2 310 ? 187.725 217.242 179.074 1.00 42.29  ? 314 GLN F N     1 
ATOM   8381 C CA    . GLN B 2 310 ? 187.511 217.997 177.853 1.00 42.29  ? 314 GLN F CA    1 
ATOM   8382 C C     . GLN B 2 310 ? 188.659 218.948 177.588 1.00 42.29  ? 314 GLN F C     1 
ATOM   8383 O O     . GLN B 2 310 ? 189.127 219.050 176.455 1.00 42.29  ? 314 GLN F O     1 
ATOM   8384 C CB    . GLN B 2 310 ? 186.191 218.743 177.910 1.00 42.29  ? 314 GLN F CB    1 
ATOM   8385 C CG    . GLN B 2 310 ? 185.957 219.575 176.689 1.00 42.29  ? 314 GLN F CG    1 
ATOM   8386 C CD    . GLN B 2 310 ? 184.545 220.037 176.580 1.00 42.29  ? 314 GLN F CD    1 
ATOM   8387 O OE1   . GLN B 2 310 ? 183.702 219.681 177.395 1.00 42.29  ? 314 GLN F OE1   1 
ATOM   8388 N NE2   . GLN B 2 310 ? 184.266 220.839 175.569 1.00 42.29  ? 314 GLN F NE2   1 
ATOM   8389 N N     . LYS B 2 311 ? 189.144 219.635 178.615 1.00 40.99  ? 315 LYS F N     1 
ATOM   8390 C CA    . LYS B 2 311 ? 190.293 220.506 178.412 1.00 40.99  ? 315 LYS F CA    1 
ATOM   8391 C C     . LYS B 2 311 ? 191.487 219.724 177.882 1.00 40.99  ? 315 LYS F C     1 
ATOM   8392 O O     . LYS B 2 311 ? 192.149 220.150 176.930 1.00 40.99  ? 315 LYS F O     1 
ATOM   8393 C CB    . LYS B 2 311 ? 190.633 221.215 179.715 1.00 40.99  ? 315 LYS F CB    1 
ATOM   8394 C CG    . LYS B 2 311 ? 191.966 221.901 179.719 1.00 40.99  ? 315 LYS F CG    1 
ATOM   8395 C CD    . LYS B 2 311 ? 192.082 222.808 180.917 1.00 40.99  ? 315 LYS F CD    1 
ATOM   8396 C CE    . LYS B 2 311 ? 193.498 223.263 181.118 1.00 40.99  ? 315 LYS F CE    1 
ATOM   8397 N NZ    . LYS B 2 311 ? 194.346 222.122 181.524 1.00 40.99  ? 315 LYS F NZ    1 
ATOM   8398 N N     . GLU B 2 312 ? 191.741 218.547 178.445 1.00 40.91  ? 316 GLU F N     1 
ATOM   8399 C CA    . GLU B 2 312 ? 192.912 217.778 178.038 1.00 40.91  ? 316 GLU F CA    1 
ATOM   8400 C C     . GLU B 2 312 ? 192.768 217.240 176.621 1.00 40.91  ? 316 GLU F C     1 
ATOM   8401 O O     . GLU B 2 312 ? 193.653 217.436 175.778 1.00 40.91  ? 316 GLU F O     1 
ATOM   8402 C CB    . GLU B 2 312 ? 193.150 216.632 179.012 1.00 40.91  ? 316 GLU F CB    1 
ATOM   8403 C CG    . GLU B 2 312 ? 193.391 217.057 180.436 1.00 40.91  ? 316 GLU F CG    1 
ATOM   8404 C CD    . GLU B 2 312 ? 194.797 217.542 180.676 1.00 40.91  ? 316 GLU F CD    1 
ATOM   8405 O OE1   . GLU B 2 312 ? 195.527 217.771 179.695 1.00 40.91  ? 316 GLU F OE1   1 
ATOM   8406 O OE2   . GLU B 2 312 ? 195.181 217.686 181.852 1.00 40.91  ? 316 GLU F OE2   1 
ATOM   8407 N N     . ILE B 2 313 ? 191.671 216.537 176.341 1.00 38.93  ? 317 ILE F N     1 
ATOM   8408 C CA    . ILE B 2 313 ? 191.474 215.974 175.013 1.00 38.93  ? 317 ILE F CA    1 
ATOM   8409 C C     . ILE B 2 313 ? 191.407 217.069 173.964 1.00 38.93  ? 317 ILE F C     1 
ATOM   8410 O O     . ILE B 2 313 ? 191.826 216.867 172.823 1.00 38.93  ? 317 ILE F O     1 
ATOM   8411 C CB    . ILE B 2 313 ? 190.214 215.096 174.995 1.00 38.93  ? 317 ILE F CB    1 
ATOM   8412 C CG1   . ILE B 2 313 ? 190.386 213.920 175.937 1.00 38.93  ? 317 ILE F CG1   1 
ATOM   8413 C CG2   . ILE B 2 313 ? 189.948 214.580 173.617 1.00 38.93  ? 317 ILE F CG2   1 
ATOM   8414 C CD1   . ILE B 2 313 ? 189.268 212.954 175.879 1.00 38.93  ? 317 ILE F CD1   1 
ATOM   8415 N N     . THR B 2 314 ? 190.900 218.247 174.323 1.00 39.09  ? 318 THR F N     1 
ATOM   8416 C CA    . THR B 2 314 ? 190.872 219.352 173.379 1.00 39.09  ? 318 THR F CA    1 
ATOM   8417 C C     . THR B 2 314 ? 192.271 219.860 173.090 1.00 39.09  ? 318 THR F C     1 
ATOM   8418 O O     . THR B 2 314 ? 192.590 220.184 171.944 1.00 39.09  ? 318 THR F O     1 
ATOM   8419 C CB    . THR B 2 314 ? 189.998 220.472 173.927 1.00 39.09  ? 318 THR F CB    1 
ATOM   8420 O OG1   . THR B 2 314 ? 188.644 220.025 173.982 1.00 39.09  ? 318 THR F OG1   1 
ATOM   8421 C CG2   . THR B 2 314 ? 190.076 221.688 173.054 1.00 39.09  ? 318 THR F CG2   1 
ATOM   8422 N N     . ALA B 2 315 ? 193.122 219.939 174.110 1.00 38.99  ? 319 ALA F N     1 
ATOM   8423 C CA    . ALA B 2 315 ? 194.500 220.333 173.854 1.00 38.99  ? 319 ALA F CA    1 
ATOM   8424 C C     . ALA B 2 315 ? 195.244 219.283 173.045 1.00 38.99  ? 319 ALA F C     1 
ATOM   8425 O O     . ALA B 2 315 ? 196.242 219.599 172.395 1.00 38.99  ? 319 ALA F O     1 
ATOM   8426 C CB    . ALA B 2 315 ? 195.225 220.592 175.168 1.00 38.99  ? 319 ALA F CB    1 
ATOM   8427 N N     . LEU B 2 316 ? 194.789 218.032 173.088 1.00 39.08  ? 320 LEU F N     1 
ATOM   8428 C CA    . LEU B 2 316 ? 195.475 216.973 172.351 1.00 39.08  ? 320 LEU F CA    1 
ATOM   8429 C C     . LEU B 2 316 ? 195.033 216.904 170.893 1.00 39.08  ? 320 LEU F C     1 
ATOM   8430 O O     . LEU B 2 316 ? 195.869 216.848 169.989 1.00 39.08  ? 320 LEU F O     1 
ATOM   8431 C CB    . LEU B 2 316 ? 195.242 215.628 173.030 1.00 39.08  ? 320 LEU F CB    1 
ATOM   8432 C CG    . LEU B 2 316 ? 196.219 215.272 174.139 1.00 39.08  ? 320 LEU F CG    1 
ATOM   8433 C CD1   . LEU B 2 316 ? 195.863 213.944 174.733 1.00 39.08  ? 320 LEU F CD1   1 
ATOM   8434 C CD2   . LEU B 2 316 ? 197.615 215.243 173.583 1.00 39.08  ? 320 LEU F CD2   1 
ATOM   8435 N N     . ALA B 2 317 ? 193.728 216.890 170.649 1.00 41.34  ? 321 ALA F N     1 
ATOM   8436 C CA    . ALA B 2 317 ? 193.182 216.696 169.321 1.00 41.34  ? 321 ALA F CA    1 
ATOM   8437 C C     . ALA B 2 317 ? 193.458 217.908 168.441 1.00 41.34  ? 321 ALA F C     1 
ATOM   8438 O O     . ALA B 2 317 ? 193.871 218.960 168.930 1.00 41.34  ? 321 ALA F O     1 
ATOM   8439 C CB    . ALA B 2 317 ? 191.683 216.431 169.412 1.00 41.34  ? 321 ALA F CB    1 
ATOM   8440 N N     . PRO B 2 318 ? 193.264 217.784 167.126 1.00 46.44  ? 322 PRO F N     1 
ATOM   8441 C CA    . PRO B 2 318 ? 193.407 218.949 166.250 1.00 46.44  ? 322 PRO F CA    1 
ATOM   8442 C C     . PRO B 2 318 ? 192.408 220.037 166.595 1.00 46.44  ? 322 PRO F C     1 
ATOM   8443 O O     . PRO B 2 318 ? 191.307 219.774 167.078 1.00 46.44  ? 322 PRO F O     1 
ATOM   8444 C CB    . PRO B 2 318 ? 193.144 218.376 164.858 1.00 46.44  ? 322 PRO F CB    1 
ATOM   8445 C CG    . PRO B 2 318 ? 193.514 216.970 164.973 1.00 46.44  ? 322 PRO F CG    1 
ATOM   8446 C CD    . PRO B 2 318 ? 193.138 216.542 166.347 1.00 46.44  ? 322 PRO F CD    1 
ATOM   8447 N N     . SER B 2 319 ? 192.799 221.273 166.311 1.00 50.22  ? 323 SER F N     1 
ATOM   8448 C CA    . SER B 2 319 ? 192.051 222.434 166.763 1.00 50.22  ? 323 SER F CA    1 
ATOM   8449 C C     . SER B 2 319 ? 190.786 222.685 165.971 1.00 50.22  ? 323 SER F C     1 
ATOM   8450 O O     . SER B 2 319 ? 190.151 223.720 166.182 1.00 50.22  ? 323 SER F O     1 
ATOM   8451 C CB    . SER B 2 319 ? 192.935 223.672 166.703 1.00 50.22  ? 323 SER F CB    1 
ATOM   8452 O OG    . SER B 2 319 ? 192.856 224.266 165.425 1.00 50.22  ? 323 SER F OG    1 
ATOM   8453 N N     . THR B 2 320 ? 190.404 221.796 165.062 1.00 49.01  ? 324 THR F N     1 
ATOM   8454 C CA    . THR B 2 320 ? 189.200 221.984 164.270 1.00 49.01  ? 324 THR F CA    1 
ATOM   8455 C C     . THR B 2 320 ? 188.129 220.950 164.570 1.00 49.01  ? 324 THR F C     1 
ATOM   8456 O O     . THR B 2 320 ? 187.203 220.784 163.774 1.00 49.01  ? 324 THR F O     1 
ATOM   8457 C CB    . THR B 2 320 ? 189.537 221.968 162.783 1.00 49.01  ? 324 THR F CB    1 
ATOM   8458 O OG1   . THR B 2 320 ? 188.340 222.163 162.025 1.00 49.01  ? 324 THR F OG1   1 
ATOM   8459 C CG2   . THR B 2 320 ? 190.166 220.659 162.400 1.00 49.01  ? 324 THR F CG2   1 
ATOM   8460 N N     . MET B 2 321 ? 188.225 220.263 165.700 1.00 46.67  ? 325 MET F N     1 
ATOM   8461 C CA    . MET B 2 321 ? 187.279 219.222 166.065 1.00 46.67  ? 325 MET F CA    1 
ATOM   8462 C C     . MET B 2 321 ? 186.407 219.688 167.218 1.00 46.67  ? 325 MET F C     1 
ATOM   8463 O O     . MET B 2 321 ? 186.798 220.553 168.002 1.00 46.67  ? 325 MET F O     1 
ATOM   8464 C CB    . MET B 2 321 ? 188.003 217.936 166.456 1.00 46.67  ? 325 MET F CB    1 
ATOM   8465 C CG    . MET B 2 321 ? 188.701 217.242 165.317 1.00 46.67  ? 325 MET F CG    1 
ATOM   8466 S SD    . MET B 2 321 ? 187.580 216.207 164.370 1.00 46.67  ? 325 MET F SD    1 
ATOM   8467 C CE    . MET B 2 321 ? 187.263 217.250 162.959 1.00 46.67  ? 325 MET F CE    1 
ATOM   8468 N N     . LYS B 2 322 ? 185.219 219.112 167.313 1.00 44.39  ? 326 LYS F N     1 
ATOM   8469 C CA    . LYS B 2 322 ? 184.307 219.384 168.418 1.00 44.39  ? 326 LYS F CA    1 
ATOM   8470 C C     . LYS B 2 322 ? 184.429 218.249 169.419 1.00 44.39  ? 326 LYS F C     1 
ATOM   8471 O O     . LYS B 2 322 ? 183.816 217.196 169.254 1.00 44.39  ? 326 LYS F O     1 
ATOM   8472 C CB    . LYS B 2 322 ? 182.872 219.527 167.933 1.00 44.39  ? 326 LYS F CB    1 
ATOM   8473 C CG    . LYS B 2 322 ? 182.488 220.939 167.566 1.00 44.39  ? 326 LYS F CG    1 
ATOM   8474 C CD    . LYS B 2 322 ? 182.925 221.275 166.160 1.00 44.39  ? 326 LYS F CD    1 
ATOM   8475 C CE    . LYS B 2 322 ? 182.213 222.506 165.643 1.00 44.39  ? 326 LYS F CE    1 
ATOM   8476 N NZ    . LYS B 2 322 ? 182.476 222.717 164.198 1.00 44.39  ? 326 LYS F NZ    1 
ATOM   8477 N N     . ILE B 2 323 ? 185.216 218.469 170.459 1.00 41.08  ? 327 ILE F N     1 
ATOM   8478 C CA    . ILE B 2 323 ? 185.344 217.518 171.551 1.00 41.08  ? 327 ILE F CA    1 
ATOM   8479 C C     . ILE B 2 323 ? 184.149 217.690 172.469 1.00 41.08  ? 327 ILE F C     1 
ATOM   8480 O O     . ILE B 2 323 ? 183.790 218.814 172.831 1.00 41.08  ? 327 ILE F O     1 
ATOM   8481 C CB    . ILE B 2 323 ? 186.653 217.733 172.316 1.00 41.08  ? 327 ILE F CB    1 
ATOM   8482 C CG1   . ILE B 2 323 ? 187.803 217.911 171.336 1.00 41.08  ? 327 ILE F CG1   1 
ATOM   8483 C CG2   . ILE B 2 323 ? 186.902 216.574 173.230 1.00 41.08  ? 327 ILE F CG2   1 
ATOM   8484 C CD1   . ILE B 2 323 ? 188.046 216.728 170.473 1.00 41.08  ? 327 ILE F CD1   1 
ATOM   8485 N N     . LYS B 2 324 ? 183.524 216.586 172.838 1.00 39.55  ? 328 LYS F N     1 
ATOM   8486 C CA    . LYS B 2 324 ? 182.317 216.640 173.637 1.00 39.55  ? 328 LYS F CA    1 
ATOM   8487 C C     . LYS B 2 324 ? 182.308 215.444 174.566 1.00 39.55  ? 328 LYS F C     1 
ATOM   8488 O O     . LYS B 2 324 ? 182.594 214.328 174.135 1.00 39.55  ? 328 LYS F O     1 
ATOM   8489 C CB    . LYS B 2 324 ? 181.087 216.648 172.734 1.00 39.55  ? 328 LYS F CB    1 
ATOM   8490 C CG    . LYS B 2 324 ? 179.775 216.753 173.456 1.00 39.55  ? 328 LYS F CG    1 
ATOM   8491 C CD    . LYS B 2 324 ? 178.741 217.444 172.590 1.00 39.55  ? 328 LYS F CD    1 
ATOM   8492 C CE    . LYS B 2 324 ? 178.744 216.902 171.173 1.00 39.55  ? 328 LYS F CE    1 
ATOM   8493 N NZ    . LYS B 2 324 ? 178.405 215.459 171.131 1.00 39.55  ? 328 LYS F NZ    1 
ATOM   8494 N N     . ILE B 2 325 ? 182.000 215.667 175.836 1.00 37.28  ? 329 ILE F N     1 
ATOM   8495 C CA    . ILE B 2 325 ? 182.064 214.610 176.834 1.00 37.28  ? 329 ILE F CA    1 
ATOM   8496 C C     . ILE B 2 325 ? 180.701 214.440 177.465 1.00 37.28  ? 329 ILE F C     1 
ATOM   8497 O O     . ILE B 2 325 ? 180.168 215.374 178.070 1.00 37.28  ? 329 ILE F O     1 
ATOM   8498 C CB    . ILE B 2 325 ? 183.131 214.888 177.893 1.00 37.28  ? 329 ILE F CB    1 
ATOM   8499 C CG1   . ILE B 2 325 ? 184.497 214.774 177.246 1.00 37.28  ? 329 ILE F CG1   1 
ATOM   8500 C CG2   . ILE B 2 325 ? 183.022 213.903 179.006 1.00 37.28  ? 329 ILE F CG2   1 
ATOM   8501 C CD1   . ILE B 2 325 ? 185.579 215.126 178.129 1.00 37.28  ? 329 ILE F CD1   1 
ATOM   8502 N N     . ILE B 2 326 ? 180.148 213.246 177.331 1.00 36.90  ? 330 ILE F N     1 
ATOM   8503 C CA    . ILE B 2 326 ? 178.819 212.916 177.813 1.00 36.90  ? 330 ILE F CA    1 
ATOM   8504 C C     . ILE B 2 326 ? 178.959 212.296 179.189 1.00 36.90  ? 330 ILE F C     1 
ATOM   8505 O O     . ILE B 2 326 ? 179.542 211.219 179.335 1.00 36.90  ? 330 ILE F O     1 
ATOM   8506 C CB    . ILE B 2 326 ? 178.107 211.961 176.850 1.00 36.90  ? 330 ILE F CB    1 
ATOM   8507 C CG1   . ILE B 2 326 ? 177.778 212.683 175.554 1.00 36.90  ? 330 ILE F CG1   1 
ATOM   8508 C CG2   . ILE B 2 326 ? 176.872 211.386 177.486 1.00 36.90  ? 330 ILE F CG2   1 
ATOM   8509 C CD1   . ILE B 2 326 ? 178.856 212.636 174.538 1.00 36.90  ? 330 ILE F CD1   1 
ATOM   8510 N N     . ALA B 2 327 ? 178.424 212.968 180.200 1.00 39.13  ? 331 ALA F N     1 
ATOM   8511 C CA    . ALA B 2 327 ? 178.532 212.527 181.584 1.00 39.13  ? 331 ALA F CA    1 
ATOM   8512 C C     . ALA B 2 327 ? 177.168 212.662 182.237 1.00 39.13  ? 331 ALA F C     1 
ATOM   8513 O O     . ALA B 2 327 ? 176.865 213.687 182.858 1.00 39.13  ? 331 ALA F O     1 
ATOM   8514 C CB    . ALA B 2 327 ? 179.586 213.335 182.331 1.00 39.13  ? 331 ALA F CB    1 
ATOM   8515 N N     . PRO B 2 328 ? 176.321 211.649 182.121 1.00 40.41  ? 332 PRO F N     1 
ATOM   8516 C CA    . PRO B 2 328 ? 174.999 211.708 182.740 1.00 40.41  ? 332 PRO F CA    1 
ATOM   8517 C C     . PRO B 2 328 ? 175.108 211.734 184.252 1.00 40.41  ? 332 PRO F C     1 
ATOM   8518 O O     . PRO B 2 328 ? 176.146 211.361 184.816 1.00 40.41  ? 332 PRO F O     1 
ATOM   8519 C CB    . PRO B 2 328 ? 174.326 210.416 182.262 1.00 40.41  ? 332 PRO F CB    1 
ATOM   8520 C CG    . PRO B 2 328 ? 175.178 209.900 181.171 1.00 40.41  ? 332 PRO F CG    1 
ATOM   8521 C CD    . PRO B 2 328 ? 176.549 210.386 181.413 1.00 40.41  ? 332 PRO F CD    1 
ATOM   8522 N N     . PRO B 2 329 ? 174.067 212.181 184.951 1.00 44.43  ? 333 PRO F N     1 
ATOM   8523 C CA    . PRO B 2 329 ? 174.097 212.099 186.416 1.00 44.43  ? 333 PRO F CA    1 
ATOM   8524 C C     . PRO B 2 329 ? 173.990 210.684 186.947 1.00 44.43  ? 333 PRO F C     1 
ATOM   8525 O O     . PRO B 2 329 ? 174.521 210.401 188.025 1.00 44.43  ? 333 PRO F O     1 
ATOM   8526 C CB    . PRO B 2 329 ? 172.896 212.952 186.833 1.00 44.43  ? 333 PRO F CB    1 
ATOM   8527 C CG    . PRO B 2 329 ? 172.676 213.857 185.698 1.00 44.43  ? 333 PRO F CG    1 
ATOM   8528 C CD    . PRO B 2 329 ? 172.988 213.057 184.484 1.00 44.43  ? 333 PRO F CD    1 
ATOM   8529 N N     . GLU B 2 330 ? 173.309 209.787 186.249 1.00 45.74  ? 334 GLU F N     1 
ATOM   8530 C CA    . GLU B 2 330 ? 173.265 208.390 186.666 1.00 45.74  ? 334 GLU F CA    1 
ATOM   8531 C C     . GLU B 2 330 ? 174.370 207.583 185.989 1.00 45.74  ? 334 GLU F C     1 
ATOM   8532 O O     . GLU B 2 330 ? 174.168 206.499 185.459 1.00 45.74  ? 334 GLU F O     1 
ATOM   8533 C CB    . GLU B 2 330 ? 171.884 207.812 186.384 1.00 45.74  ? 334 GLU F CB    1 
ATOM   8534 C CG    . GLU B 2 330 ? 171.492 207.697 184.914 1.00 45.74  ? 334 GLU F CG    1 
ATOM   8535 C CD    . GLU B 2 330 ? 171.294 209.031 184.214 1.00 45.74  ? 334 GLU F CD    1 
ATOM   8536 O OE1   . GLU B 2 330 ? 171.528 210.087 184.833 1.00 45.74  ? 334 GLU F OE1   1 
ATOM   8537 O OE2   . GLU B 2 330 ? 170.907 209.021 183.028 1.00 45.74  ? 334 GLU F OE2   1 
ATOM   8538 N N     . ARG B 2 331 ? 175.584 208.124 186.049 1.00 38.85  ? 335 ARG F N     1 
ATOM   8539 C CA    . ARG B 2 331 ? 176.739 207.450 185.475 1.00 38.85  ? 335 ARG F CA    1 
ATOM   8540 C C     . ARG B 2 331 ? 176.990 206.120 186.156 1.00 38.85  ? 335 ARG F C     1 
ATOM   8541 O O     . ARG B 2 331 ? 177.188 205.100 185.494 1.00 38.85  ? 335 ARG F O     1 
ATOM   8542 C CB    . ARG B 2 331 ? 177.967 208.330 185.619 1.00 38.85  ? 335 ARG F CB    1 
ATOM   8543 C CG    . ARG B 2 331 ? 178.446 208.941 184.380 1.00 38.85  ? 335 ARG F CG    1 
ATOM   8544 C CD    . ARG B 2 331 ? 179.440 209.981 184.740 1.00 38.85  ? 335 ARG F CD    1 
ATOM   8545 N NE    . ARG B 2 331 ? 178.805 211.063 185.459 1.00 38.85  ? 335 ARG F NE    1 
ATOM   8546 C CZ    . ARG B 2 331 ? 179.452 212.116 185.922 1.00 38.85  ? 335 ARG F CZ    1 
ATOM   8547 N NH1   . ARG B 2 331 ? 180.751 212.216 185.744 1.00 38.85  ? 335 ARG F NH1   1 
ATOM   8548 N NH2   . ARG B 2 331 ? 178.802 213.063 186.564 1.00 38.85  ? 335 ARG F NH2   1 
ATOM   8549 N N     . LYS B 2 332 ? 176.993 206.115 187.487 1.00 39.95  ? 336 LYS F N     1 
ATOM   8550 C CA    . LYS B 2 332 ? 177.448 204.950 188.229 1.00 39.95  ? 336 LYS F CA    1 
ATOM   8551 C C     . LYS B 2 332 ? 176.663 203.700 187.869 1.00 39.95  ? 336 LYS F C     1 
ATOM   8552 O O     . LYS B 2 332 ? 177.194 202.591 187.956 1.00 39.95  ? 336 LYS F O     1 
ATOM   8553 C CB    . LYS B 2 332 ? 177.355 205.224 189.726 1.00 39.95  ? 336 LYS F CB    1 
ATOM   8554 C CG    . LYS B 2 332 ? 177.620 204.012 190.591 1.00 39.95  ? 336 LYS F CG    1 
ATOM   8555 C CD    . LYS B 2 332 ? 177.514 204.318 192.065 1.00 39.95  ? 336 LYS F CD    1 
ATOM   8556 C CE    . LYS B 2 332 ? 178.748 205.007 192.568 1.00 39.95  ? 336 LYS F CE    1 
ATOM   8557 N NZ    . LYS B 2 332 ? 178.762 205.016 194.046 1.00 39.95  ? 336 LYS F NZ    1 
ATOM   8558 N N     . TYR B 2 333 ? 175.415 203.848 187.440 1.00 39.19  ? 337 TYR F N     1 
ATOM   8559 C CA    . TYR B 2 333 ? 174.566 202.698 187.171 1.00 39.19  ? 337 TYR F CA    1 
ATOM   8560 C C     . TYR B 2 333 ? 174.357 202.455 185.686 1.00 39.19  ? 337 TYR F C     1 
ATOM   8561 O O     . TYR B 2 333 ? 173.465 201.689 185.315 1.00 39.19  ? 337 TYR F O     1 
ATOM   8562 C CB    . TYR B 2 333 ? 173.228 202.867 187.878 1.00 39.19  ? 337 TYR F CB    1 
ATOM   8563 C CG    . TYR B 2 333 ? 173.384 203.280 189.311 1.00 39.19  ? 337 TYR F CG    1 
ATOM   8564 C CD1   . TYR B 2 333 ? 173.593 202.342 190.296 1.00 39.19  ? 337 TYR F CD1   1 
ATOM   8565 C CD2   . TYR B 2 333 ? 173.341 204.609 189.676 1.00 39.19  ? 337 TYR F CD2   1 
ATOM   8566 C CE1   . TYR B 2 333 ? 173.747 202.711 191.598 1.00 39.19  ? 337 TYR F CE1   1 
ATOM   8567 C CE2   . TYR B 2 333 ? 173.493 204.986 190.977 1.00 39.19  ? 337 TYR F CE2   1 
ATOM   8568 C CZ    . TYR B 2 333 ? 173.696 204.031 191.935 1.00 39.19  ? 337 TYR F CZ    1 
ATOM   8569 O OH    . TYR B 2 333 ? 173.851 204.398 193.246 1.00 39.19  ? 337 TYR F OH    1 
ATOM   8570 N N     . SER B 2 334 ? 175.173 203.071 184.830 1.00 37.21  ? 338 SER F N     1 
ATOM   8571 C CA    . SER B 2 334 ? 174.959 202.957 183.394 1.00 37.21  ? 338 SER F CA    1 
ATOM   8572 C C     . SER B 2 334 ? 175.087 201.523 182.919 1.00 37.21  ? 338 SER F C     1 
ATOM   8573 O O     . SER B 2 334 ? 174.313 201.076 182.070 1.00 37.21  ? 338 SER F O     1 
ATOM   8574 C CB    . SER B 2 334 ? 175.936 203.845 182.641 1.00 37.21  ? 338 SER F CB    1 
ATOM   8575 O OG    . SER B 2 334 ? 175.628 205.206 182.835 1.00 37.21  ? 338 SER F OG    1 
ATOM   8576 N N     . VAL B 2 335 ? 176.059 200.788 183.444 1.00 36.48  ? 339 VAL F N     1 
ATOM   8577 C CA    . VAL B 2 335 ? 176.233 199.405 183.022 1.00 36.48  ? 339 VAL F CA    1 
ATOM   8578 C C     . VAL B 2 335 ? 175.004 198.586 183.365 1.00 36.48  ? 339 VAL F C     1 
ATOM   8579 O O     . VAL B 2 335 ? 174.528 197.789 182.554 1.00 36.48  ? 339 VAL F O     1 
ATOM   8580 C CB    . VAL B 2 335 ? 177.497 198.809 183.648 1.00 36.48  ? 339 VAL F CB    1 
ATOM   8581 C CG1   . VAL B 2 335 ? 177.711 197.431 183.125 1.00 36.48  ? 339 VAL F CG1   1 
ATOM   8582 C CG2   . VAL B 2 335 ? 178.673 199.676 183.338 1.00 36.48  ? 339 VAL F CG2   1 
ATOM   8583 N N     . TRP B 2 336 ? 174.445 198.788 184.554 1.00 40.20  ? 340 TRP F N     1 
ATOM   8584 C CA    . TRP B 2 336 ? 173.265 198.021 184.917 1.00 40.20  ? 340 TRP F CA    1 
ATOM   8585 C C     . TRP B 2 336 ? 172.068 198.424 184.074 1.00 40.20  ? 340 TRP F C     1 
ATOM   8586 O O     . TRP B 2 336 ? 171.287 197.567 183.650 1.00 40.20  ? 340 TRP F O     1 
ATOM   8587 C CB    . TRP B 2 336 ? 172.943 198.178 186.399 1.00 40.20  ? 340 TRP F CB    1 
ATOM   8588 C CG    . TRP B 2 336 ? 171.936 197.186 186.812 1.00 40.20  ? 340 TRP F CG    1 
ATOM   8589 C CD1   . TRP B 2 336 ? 172.169 195.983 187.370 1.00 40.20  ? 340 TRP F CD1   1 
ATOM   8590 C CD2   . TRP B 2 336 ? 170.525 197.285 186.650 1.00 40.20  ? 340 TRP F CD2   1 
ATOM   8591 N NE1   . TRP B 2 336 ? 170.998 195.320 187.580 1.00 40.20  ? 340 TRP F NE1   1 
ATOM   8592 C CE2   . TRP B 2 336 ? 169.970 196.104 187.140 1.00 40.20  ? 340 TRP F CE2   1 
ATOM   8593 C CE3   . TRP B 2 336 ? 169.678 198.262 186.136 1.00 40.20  ? 340 TRP F CE3   1 
ATOM   8594 C CZ2   . TRP B 2 336 ? 168.612 195.872 187.137 1.00 40.20  ? 340 TRP F CZ2   1 
ATOM   8595 C CZ3   . TRP B 2 336 ? 168.341 198.026 186.129 1.00 40.20  ? 340 TRP F CZ3   1 
ATOM   8596 C CH2   . TRP B 2 336 ? 167.816 196.847 186.632 1.00 40.20  ? 340 TRP F CH2   1 
ATOM   8597 N N     . ILE B 2 337 ? 171.893 199.721 183.833 1.00 37.52  ? 341 ILE F N     1 
ATOM   8598 C CA    . ILE B 2 337 ? 170.755 200.170 183.038 1.00 37.52  ? 341 ILE F CA    1 
ATOM   8599 C C     . ILE B 2 337 ? 170.822 199.577 181.641 1.00 37.52  ? 341 ILE F C     1 
ATOM   8600 O O     . ILE B 2 337 ? 169.838 199.028 181.128 1.00 37.52  ? 341 ILE F O     1 
ATOM   8601 C CB    . ILE B 2 337 ? 170.704 201.703 182.998 1.00 37.52  ? 341 ILE F CB    1 
ATOM   8602 C CG1   . ILE B 2 337 ? 170.421 202.253 184.383 1.00 37.52  ? 341 ILE F CG1   1 
ATOM   8603 C CG2   . ILE B 2 337 ? 169.640 202.163 182.060 1.00 37.52  ? 341 ILE F CG2   1 
ATOM   8604 C CD1   . ILE B 2 337 ? 170.660 203.700 184.485 1.00 37.52  ? 341 ILE F CD1   1 
ATOM   8605 N N     . GLY B 2 338 ? 171.986 199.670 181.008 1.00 38.20  ? 342 GLY F N     1 
ATOM   8606 C CA    . GLY B 2 338 ? 172.153 199.062 179.706 1.00 38.20  ? 342 GLY F CA    1 
ATOM   8607 C C     . GLY B 2 338 ? 171.940 197.565 179.728 1.00 38.20  ? 342 GLY F C     1 
ATOM   8608 O O     . GLY B 2 338 ? 171.398 196.998 178.783 1.00 38.20  ? 342 GLY F O     1 
ATOM   8609 N N     . GLY B 2 339 ? 172.368 196.903 180.798 1.00 39.26  ? 343 GLY F N     1 
ATOM   8610 C CA    . GLY B 2 339 ? 172.131 195.476 180.897 1.00 39.26  ? 343 GLY F CA    1 
ATOM   8611 C C     . GLY B 2 339 ? 170.658 195.142 180.940 1.00 39.26  ? 343 GLY F C     1 
ATOM   8612 O O     . GLY B 2 339 ? 170.214 194.171 180.328 1.00 39.26  ? 343 GLY F O     1 
ATOM   8613 N N     . SER B 2 340 ? 169.880 195.948 181.661 1.00 42.52  ? 344 SER F N     1 
ATOM   8614 C CA    . SER B 2 340 ? 168.441 195.723 181.725 1.00 42.52  ? 344 SER F CA    1 
ATOM   8615 C C     . SER B 2 340 ? 167.801 195.926 180.362 1.00 42.52  ? 344 SER F C     1 
ATOM   8616 O O     . SER B 2 340 ? 166.990 195.108 179.913 1.00 42.52  ? 344 SER F O     1 
ATOM   8617 C CB    . SER B 2 340 ? 167.808 196.650 182.749 1.00 42.52  ? 344 SER F CB    1 
ATOM   8618 O OG    . SER B 2 340 ? 167.662 197.939 182.209 1.00 42.52  ? 344 SER F OG    1 
ATOM   8619 N N     . ILE B 2 341 ? 168.162 197.016 179.688 1.00 41.72  ? 345 ILE F N     1 
ATOM   8620 C CA    . ILE B 2 341 ? 167.674 197.250 178.330 1.00 41.72  ? 345 ILE F CA    1 
ATOM   8621 C C     . ILE B 2 341 ? 167.972 196.050 177.442 1.00 41.72  ? 345 ILE F C     1 
ATOM   8622 O O     . ILE B 2 341 ? 167.086 195.519 176.764 1.00 41.72  ? 345 ILE F O     1 
ATOM   8623 C CB    . ILE B 2 341 ? 168.296 198.529 177.754 1.00 41.72  ? 345 ILE F CB    1 
ATOM   8624 C CG1   . ILE B 2 341 ? 167.726 199.755 178.447 1.00 41.72  ? 345 ILE F CG1   1 
ATOM   8625 C CG2   . ILE B 2 341 ? 168.045 198.606 176.288 1.00 41.72  ? 345 ILE F CG2   1 
ATOM   8626 C CD1   . ILE B 2 341 ? 168.357 201.026 178.003 1.00 41.72  ? 345 ILE F CD1   1 
ATOM   8627 N N     . LEU B 2 342 ? 169.229 195.613 177.431 1.00 42.31  ? 346 LEU F N     1 
ATOM   8628 C CA    . LEU B 2 342 ? 169.642 194.520 176.562 1.00 42.31  ? 346 LEU F CA    1 
ATOM   8629 C C     . LEU B 2 342 ? 168.872 193.246 176.862 1.00 42.31  ? 346 LEU F C     1 
ATOM   8630 O O     . LEU B 2 342 ? 168.371 192.585 175.951 1.00 42.31  ? 346 LEU F O     1 
ATOM   8631 C CB    . LEU B 2 342 ? 171.139 194.278 176.710 1.00 42.31  ? 346 LEU F CB    1 
ATOM   8632 C CG    . LEU B 2 342 ? 171.661 193.028 176.018 1.00 42.31  ? 346 LEU F CG    1 
ATOM   8633 C CD1   . LEU B 2 342 ? 171.547 193.178 174.539 1.00 42.31  ? 346 LEU F CD1   1 
ATOM   8634 C CD2   . LEU B 2 342 ? 173.089 192.772 176.400 1.00 42.31  ? 346 LEU F CD2   1 
ATOM   8635 N N     . ALA B 2 343 ? 168.777 192.871 178.133 1.00 45.26  ? 347 ALA F N     1 
ATOM   8636 C CA    . ALA B 2 343 ? 168.088 191.634 178.455 1.00 45.26  ? 347 ALA F CA    1 
ATOM   8637 C C     . ALA B 2 343 ? 166.599 191.723 178.187 1.00 45.26  ? 347 ALA F C     1 
ATOM   8638 O O     . ALA B 2 343 ? 165.957 190.687 178.006 1.00 45.26  ? 347 ALA F O     1 
ATOM   8639 C CB    . ALA B 2 343 ? 168.334 191.250 179.909 1.00 45.26  ? 347 ALA F CB    1 
ATOM   8640 N N     . SER B 2 344 ? 166.031 192.926 178.153 1.00 47.75  ? 348 SER F N     1 
ATOM   8641 C CA    . SER B 2 344 ? 164.618 193.031 177.823 1.00 47.75  ? 348 SER F CA    1 
ATOM   8642 C C     . SER B 2 344 ? 164.363 193.069 176.326 1.00 47.75  ? 348 SER F C     1 
ATOM   8643 O O     . SER B 2 344 ? 163.243 192.781 175.903 1.00 47.75  ? 348 SER F O     1 
ATOM   8644 C CB    . SER B 2 344 ? 164.013 194.272 178.461 1.00 47.75  ? 348 SER F CB    1 
ATOM   8645 O OG    . SER B 2 344 ? 164.118 195.366 177.585 1.00 47.75  ? 348 SER F OG    1 
ATOM   8646 N N     . LEU B 2 345 ? 165.362 193.428 175.521 1.00 52.35  ? 349 LEU F N     1 
ATOM   8647 C CA    . LEU B 2 345 ? 165.195 193.390 174.071 1.00 52.35  ? 349 LEU F CA    1 
ATOM   8648 C C     . LEU B 2 345 ? 164.648 192.042 173.636 1.00 52.35  ? 349 LEU F C     1 
ATOM   8649 O O     . LEU B 2 345 ? 165.011 191.003 174.182 1.00 52.35  ? 349 LEU F O     1 
ATOM   8650 C CB    . LEU B 2 345 ? 166.520 193.643 173.357 1.00 52.35  ? 349 LEU F CB    1 
ATOM   8651 C CG    . LEU B 2 345 ? 167.016 195.077 173.306 1.00 52.35  ? 349 LEU F CG    1 
ATOM   8652 C CD1   . LEU B 2 345 ? 168.046 195.215 172.225 1.00 52.35  ? 349 LEU F CD1   1 
ATOM   8653 C CD2   . LEU B 2 345 ? 165.866 196.006 173.072 1.00 52.35  ? 349 LEU F CD2   1 
ATOM   8654 N N     . SER B 2 346 ? 163.762 192.059 172.653 1.00 62.33  ? 350 SER F N     1 
ATOM   8655 C CA    . SER B 2 346 ? 163.179 190.808 172.203 1.00 62.33  ? 350 SER F CA    1 
ATOM   8656 C C     . SER B 2 346 ? 164.089 190.067 171.237 1.00 62.33  ? 350 SER F C     1 
ATOM   8657 O O     . SER B 2 346 ? 164.013 188.839 171.146 1.00 62.33  ? 350 SER F O     1 
ATOM   8658 C CB    . SER B 2 346 ? 161.833 191.059 171.547 1.00 62.33  ? 350 SER F CB    1 
ATOM   8659 O OG    . SER B 2 346 ? 161.472 189.931 170.785 1.00 62.33  ? 350 SER F OG    1 
ATOM   8660 N N     . THR B 2 347 ? 164.943 190.784 170.503 1.00 61.08  ? 351 THR F N     1 
ATOM   8661 C CA    . THR B 2 347 ? 165.923 190.117 169.656 1.00 61.08  ? 351 THR F CA    1 
ATOM   8662 C C     . THR B 2 347 ? 166.901 189.289 170.467 1.00 61.08  ? 351 THR F C     1 
ATOM   8663 O O     . THR B 2 347 ? 167.399 188.275 169.976 1.00 61.08  ? 351 THR F O     1 
ATOM   8664 C CB    . THR B 2 347 ? 166.684 191.143 168.825 1.00 61.08  ? 351 THR F CB    1 
ATOM   8665 O OG1   . THR B 2 347 ? 165.759 191.867 168.014 1.00 61.08  ? 351 THR F OG1   1 
ATOM   8666 C CG2   . THR B 2 347 ? 167.675 190.468 167.923 1.00 61.08  ? 351 THR F CG2   1 
ATOM   8667 N N     . PHE B 2 348 ? 167.157 189.675 171.707 1.00 53.16  ? 352 PHE F N     1 
ATOM   8668 C CA    . PHE B 2 348 ? 168.162 189.032 172.535 1.00 53.16  ? 352 PHE F CA    1 
ATOM   8669 C C     . PHE B 2 348 ? 167.758 187.643 172.997 1.00 53.16  ? 352 PHE F C     1 
ATOM   8670 O O     . PHE B 2 348 ? 168.615 186.897 173.469 1.00 53.16  ? 352 PHE F O     1 
ATOM   8671 C CB    . PHE B 2 348 ? 168.445 189.920 173.745 1.00 53.16  ? 352 PHE F CB    1 
ATOM   8672 C CG    . PHE B 2 348 ? 169.566 189.452 174.603 1.00 53.16  ? 352 PHE F CG    1 
ATOM   8673 C CD1   . PHE B 2 348 ? 170.868 189.685 174.242 1.00 53.16  ? 352 PHE F CD1   1 
ATOM   8674 C CD2   . PHE B 2 348 ? 169.317 188.817 175.792 1.00 53.16  ? 352 PHE F CD2   1 
ATOM   8675 C CE1   . PHE B 2 348 ? 171.893 189.268 175.034 1.00 53.16  ? 352 PHE F CE1   1 
ATOM   8676 C CE2   . PHE B 2 348 ? 170.343 188.401 176.584 1.00 53.16  ? 352 PHE F CE2   1 
ATOM   8677 C CZ    . PHE B 2 348 ? 171.629 188.626 176.206 1.00 53.16  ? 352 PHE F CZ    1 
ATOM   8678 N N     . GLN B 2 349 ? 166.493 187.266 172.853 1.00 55.54  ? 353 GLN F N     1 
ATOM   8679 C CA    . GLN B 2 349 ? 166.010 186.060 173.507 1.00 55.54  ? 353 GLN F CA    1 
ATOM   8680 C C     . GLN B 2 349 ? 166.537 184.776 172.887 1.00 55.54  ? 353 GLN F C     1 
ATOM   8681 O O     . GLN B 2 349 ? 166.339 183.708 173.472 1.00 55.54  ? 353 GLN F O     1 
ATOM   8682 C CB    . GLN B 2 349 ? 164.488 186.042 173.512 1.00 55.54  ? 353 GLN F CB    1 
ATOM   8683 C CG    . GLN B 2 349 ? 163.880 187.244 174.192 1.00 55.54  ? 353 GLN F CG    1 
ATOM   8684 C CD    . GLN B 2 349 ? 164.477 187.508 175.553 1.00 55.54  ? 353 GLN F CD    1 
ATOM   8685 O OE1   . GLN B 2 349 ? 164.927 188.613 175.841 1.00 55.54  ? 353 GLN F OE1   1 
ATOM   8686 N NE2   . GLN B 2 349 ? 164.479 186.495 176.403 1.00 55.54  ? 353 GLN F NE2   1 
ATOM   8687 N N     . GLN B 2 350 ? 167.186 184.836 171.730 1.00 58.19  ? 354 GLN F N     1 
ATOM   8688 C CA    . GLN B 2 350 ? 167.841 183.661 171.179 1.00 58.19  ? 354 GLN F CA    1 
ATOM   8689 C C     . GLN B 2 350 ? 169.353 183.750 171.268 1.00 58.19  ? 354 GLN F C     1 
ATOM   8690 O O     . GLN B 2 350 ? 170.050 182.998 170.587 1.00 58.19  ? 354 GLN F O     1 
ATOM   8691 C CB    . GLN B 2 350 ? 167.413 183.430 169.732 1.00 58.19  ? 354 GLN F CB    1 
ATOM   8692 C CG    . GLN B 2 350 ? 167.966 184.426 168.751 1.00 58.19  ? 354 GLN F CG    1 
ATOM   8693 C CD    . GLN B 2 350 ? 167.152 185.688 168.712 1.00 58.19  ? 354 GLN F CD    1 
ATOM   8694 O OE1   . GLN B 2 350 ? 166.075 185.762 169.303 1.00 58.19  ? 354 GLN F OE1   1 
ATOM   8695 N NE2   . GLN B 2 350 ? 167.661 186.700 168.016 1.00 58.19  ? 354 GLN F NE2   1 
ATOM   8696 N N     . MET B 2 351 ? 169.874 184.645 172.096 1.00 56.82  ? 355 MET F N     1 
ATOM   8697 C CA    . MET B 2 351 ? 171.303 184.752 172.311 1.00 56.82  ? 355 MET F CA    1 
ATOM   8698 C C     . MET B 2 351 ? 171.727 184.329 173.705 1.00 56.82  ? 355 MET F C     1 
ATOM   8699 O O     . MET B 2 351 ? 172.917 184.394 174.017 1.00 56.82  ? 355 MET F O     1 
ATOM   8700 C CB    . MET B 2 351 ? 171.765 186.178 172.031 1.00 56.82  ? 355 MET F CB    1 
ATOM   8701 C CG    . MET B 2 351 ? 171.478 186.605 170.617 1.00 56.82  ? 355 MET F CG    1 
ATOM   8702 S SD    . MET B 2 351 ? 172.495 187.990 170.139 1.00 56.82  ? 355 MET F SD    1 
ATOM   8703 C CE    . MET B 2 351 ? 174.098 187.370 170.625 1.00 56.82  ? 355 MET F CE    1 
ATOM   8704 N N     . TRP B 2 352 ? 170.794 183.905 174.549 1.00 52.91  ? 356 TRP F N     1 
ATOM   8705 C CA    . TRP B 2 352 ? 171.168 183.292 175.808 1.00 52.91  ? 356 TRP F CA    1 
ATOM   8706 C C     . TRP B 2 352 ? 171.914 181.993 175.550 1.00 52.91  ? 356 TRP F C     1 
ATOM   8707 O O     . TRP B 2 352 ? 171.819 181.396 174.480 1.00 52.91  ? 356 TRP F O     1 
ATOM   8708 C CB    . TRP B 2 352 ? 169.940 182.991 176.656 1.00 52.91  ? 356 TRP F CB    1 
ATOM   8709 C CG    . TRP B 2 352 ? 169.149 184.165 177.057 1.00 52.91  ? 356 TRP F CG    1 
ATOM   8710 C CD1   . TRP B 2 352 ? 168.020 184.614 176.474 1.00 52.91  ? 356 TRP F CD1   1 
ATOM   8711 C CD2   . TRP B 2 352 ? 169.403 185.032 178.161 1.00 52.91  ? 356 TRP F CD2   1 
ATOM   8712 N NE1   . TRP B 2 352 ? 167.554 185.717 177.130 1.00 52.91  ? 356 TRP F NE1   1 
ATOM   8713 C CE2   . TRP B 2 352 ? 168.391 185.995 178.173 1.00 52.91  ? 356 TRP F CE2   1 
ATOM   8714 C CE3   . TRP B 2 352 ? 170.394 185.091 179.136 1.00 52.91  ? 356 TRP F CE3   1 
ATOM   8715 C CZ2   . TRP B 2 352 ? 168.337 187.001 179.114 1.00 52.91  ? 356 TRP F CZ2   1 
ATOM   8716 C CZ3   . TRP B 2 352 ? 170.338 186.089 180.067 1.00 52.91  ? 356 TRP F CZ3   1 
ATOM   8717 C CH2   . TRP B 2 352 ? 169.320 187.032 180.052 1.00 52.91  ? 356 TRP F CH2   1 
ATOM   8718 N N     . ILE B 2 353 ? 172.662 181.555 176.550 1.00 53.95  ? 357 ILE F N     1 
ATOM   8719 C CA    . ILE B 2 353 ? 173.273 180.236 176.556 1.00 53.95  ? 357 ILE F CA    1 
ATOM   8720 C C     . ILE B 2 353 ? 172.382 179.351 177.404 1.00 53.95  ? 357 ILE F C     1 
ATOM   8721 O O     . ILE B 2 353 ? 172.262 179.565 178.611 1.00 53.95  ? 357 ILE F O     1 
ATOM   8722 C CB    . ILE B 2 353 ? 174.697 180.271 177.111 1.00 53.95  ? 357 ILE F CB    1 
ATOM   8723 C CG1   . ILE B 2 353 ? 175.547 181.264 176.333 1.00 53.95  ? 357 ILE F CG1   1 
ATOM   8724 C CG2   . ILE B 2 353 ? 175.300 178.903 177.062 1.00 53.95  ? 357 ILE F CG2   1 
ATOM   8725 C CD1   . ILE B 2 353 ? 176.841 181.594 177.009 1.00 53.95  ? 357 ILE F CD1   1 
ATOM   8726 N N     . SER B 2 354 ? 171.747 178.363 176.793 1.00 58.57  ? 358 SER F N     1 
ATOM   8727 C CA    . SER B 2 354 ? 170.797 177.557 177.536 1.00 58.57  ? 358 SER F CA    1 
ATOM   8728 C C     . SER B 2 354 ? 171.511 176.447 178.296 1.00 58.57  ? 358 SER F C     1 
ATOM   8729 O O     . SER B 2 354 ? 172.680 176.150 178.066 1.00 58.57  ? 358 SER F O     1 
ATOM   8730 C CB    . SER B 2 354 ? 169.748 176.972 176.602 1.00 58.57  ? 358 SER F CB    1 
ATOM   8731 O OG    . SER B 2 354 ? 170.228 175.791 175.996 1.00 58.57  ? 358 SER F OG    1 
ATOM   8732 N N     . LYS B 2 355 ? 170.781 175.832 179.224 1.00 60.29  ? 359 LYS F N     1 
ATOM   8733 C CA    . LYS B 2 355 ? 171.334 174.723 179.991 1.00 60.29  ? 359 LYS F CA    1 
ATOM   8734 C C     . LYS B 2 355 ? 171.642 173.537 179.091 1.00 60.29  ? 359 LYS F C     1 
ATOM   8735 O O     . LYS B 2 355 ? 172.620 172.814 179.311 1.00 60.29  ? 359 LYS F O     1 
ATOM   8736 C CB    . LYS B 2 355 ? 170.355 174.319 181.088 1.00 60.29  ? 359 LYS F CB    1 
ATOM   8737 C CG    . LYS B 2 355 ? 170.827 173.197 181.980 1.00 60.29  ? 359 LYS F CG    1 
ATOM   8738 C CD    . LYS B 2 355 ? 171.940 173.652 182.898 1.00 60.29  ? 359 LYS F CD    1 
ATOM   8739 C CE    . LYS B 2 355 ? 172.261 172.592 183.933 1.00 60.29  ? 359 LYS F CE    1 
ATOM   8740 N NZ    . LYS B 2 355 ? 171.091 172.323 184.812 1.00 60.29  ? 359 LYS F NZ    1 
ATOM   8741 N N     . GLN B 2 356 ? 170.818 173.325 178.070 1.00 64.61  ? 360 GLN F N     1 
ATOM   8742 C CA    . GLN B 2 356 ? 171.064 172.241 177.131 1.00 64.61  ? 360 GLN F CA    1 
ATOM   8743 C C     . GLN B 2 356 ? 172.368 172.456 176.376 1.00 64.61  ? 360 GLN F C     1 
ATOM   8744 O O     . GLN B 2 356 ? 173.188 171.540 176.259 1.00 64.61  ? 360 GLN F O     1 
ATOM   8745 C CB    . GLN B 2 356 ? 169.889 172.122 176.164 1.00 64.61  ? 360 GLN F CB    1 
ATOM   8746 C CG    . GLN B 2 356 ? 170.182 171.300 174.924 1.00 64.61  ? 360 GLN F CG    1 
ATOM   8747 C CD    . GLN B 2 356 ? 170.711 169.924 175.257 1.00 64.61  ? 360 GLN F CD    1 
ATOM   8748 O OE1   . GLN B 2 356 ? 170.260 169.288 176.208 1.00 64.61  ? 360 GLN F OE1   1 
ATOM   8749 N NE2   . GLN B 2 356 ? 171.684 169.460 174.481 1.00 64.61  ? 360 GLN F NE2   1 
ATOM   8750 N N     . GLU B 2 357 ? 172.570 173.662 175.843 1.00 63.82  ? 361 GLU F N     1 
ATOM   8751 C CA    . GLU B 2 357 ? 173.812 173.961 175.141 1.00 63.82  ? 361 GLU F CA    1 
ATOM   8752 C C     . GLU B 2 357 ? 175.016 173.720 176.035 1.00 63.82  ? 361 GLU F C     1 
ATOM   8753 O O     . GLU B 2 357 ? 176.040 173.195 175.582 1.00 63.82  ? 361 GLU F O     1 
ATOM   8754 C CB    . GLU B 2 357 ? 173.802 175.403 174.644 1.00 63.82  ? 361 GLU F CB    1 
ATOM   8755 C CG    . GLU B 2 357 ? 172.915 175.649 173.444 1.00 63.82  ? 361 GLU F CG    1 
ATOM   8756 C CD    . GLU B 2 357 ? 172.772 177.127 173.113 1.00 63.82  ? 361 GLU F CD    1 
ATOM   8757 O OE1   . GLU B 2 357 ? 171.923 177.800 173.730 1.00 63.82  ? 361 GLU F OE1   1 
ATOM   8758 O OE2   . GLU B 2 357 ? 173.512 177.619 172.238 1.00 63.82  ? 361 GLU F OE2   1 
ATOM   8759 N N     . TYR B 2 358 ? 174.912 174.091 177.310 1.00 61.80  ? 362 TYR F N     1 
ATOM   8760 C CA    . TYR B 2 358 ? 176.025 173.885 178.226 1.00 61.80  ? 362 TYR F CA    1 
ATOM   8761 C C     . TYR B 2 358 ? 176.282 172.402 178.451 1.00 61.80  ? 362 TYR F C     1 
ATOM   8762 O O     . TYR B 2 358 ? 177.402 171.923 178.263 1.00 61.80  ? 362 TYR F O     1 
ATOM   8763 C CB    . TYR B 2 358 ? 175.757 174.587 179.552 1.00 61.80  ? 362 TYR F CB    1 
ATOM   8764 C CG    . TYR B 2 358 ? 176.821 174.327 180.589 1.00 61.80  ? 362 TYR F CG    1 
ATOM   8765 C CD1   . TYR B 2 358 ? 178.011 175.025 180.576 1.00 61.80  ? 362 TYR F CD1   1 
ATOM   8766 C CD2   . TYR B 2 358 ? 176.634 173.383 181.576 1.00 61.80  ? 362 TYR F CD2   1 
ATOM   8767 C CE1   . TYR B 2 358 ? 178.977 174.790 181.514 1.00 61.80  ? 362 TYR F CE1   1 
ATOM   8768 C CE2   . TYR B 2 358 ? 177.594 173.142 182.514 1.00 61.80  ? 362 TYR F CE2   1 
ATOM   8769 C CZ    . TYR B 2 358 ? 178.762 173.848 182.481 1.00 61.80  ? 362 TYR F CZ    1 
ATOM   8770 O OH    . TYR B 2 358 ? 179.724 173.602 183.425 1.00 61.80  ? 362 TYR F OH    1 
ATOM   8771 N N     . ASP B 2 359 ? 175.253 171.654 178.854 1.00 65.99  ? 363 ASP F N     1 
ATOM   8772 C CA    . ASP B 2 359 ? 175.428 170.218 179.049 1.00 65.99  ? 363 ASP F CA    1 
ATOM   8773 C C     . ASP B 2 359 ? 175.947 169.546 177.791 1.00 65.99  ? 363 ASP F C     1 
ATOM   8774 O O     . ASP B 2 359 ? 176.555 168.474 177.863 1.00 65.99  ? 363 ASP F O     1 
ATOM   8775 C CB    . ASP B 2 359 ? 174.112 169.577 179.474 1.00 65.99  ? 363 ASP F CB    1 
ATOM   8776 C CG    . ASP B 2 359 ? 173.663 170.029 180.839 1.00 65.99  ? 363 ASP F CG    1 
ATOM   8777 O OD1   . ASP B 2 359 ? 174.520 170.141 181.737 1.00 65.99  ? 363 ASP F OD1   1 
ATOM   8778 O OD2   . ASP B 2 359 ? 172.452 170.273 181.016 1.00 65.99  ? 363 ASP F OD2   1 
ATOM   8779 N N     . GLU B 2 360 ? 175.720 170.157 176.634 1.00 67.69  ? 364 GLU F N     1 
ATOM   8780 C CA    . GLU B 2 360 ? 176.200 169.590 175.386 1.00 67.69  ? 364 GLU F CA    1 
ATOM   8781 C C     . GLU B 2 360 ? 177.684 169.866 175.182 1.00 67.69  ? 364 GLU F C     1 
ATOM   8782 O O     . GLU B 2 360 ? 178.455 168.948 174.891 1.00 67.69  ? 364 GLU F O     1 
ATOM   8783 C CB    . GLU B 2 360 ? 175.376 170.150 174.226 1.00 67.69  ? 364 GLU F CB    1 
ATOM   8784 C CG    . GLU B 2 360 ? 175.481 169.380 172.929 1.00 67.69  ? 364 GLU F CG    1 
ATOM   8785 C CD    . GLU B 2 360 ? 176.684 169.782 172.111 1.00 67.69  ? 364 GLU F CD    1 
ATOM   8786 O OE1   . GLU B 2 360 ? 177.287 168.897 171.469 1.00 67.69  ? 364 GLU F OE1   1 
ATOM   8787 O OE2   . GLU B 2 360 ? 177.027 170.983 172.113 1.00 67.69  ? 364 GLU F OE2   1 
ATOM   8788 N N     . ALA B 2 361 ? 178.107 171.120 175.344 1.00 66.34  ? 365 ALA F N     1 
ATOM   8789 C CA    . ALA B 2 361 ? 179.420 171.546 174.877 1.00 66.34  ? 365 ALA F CA    1 
ATOM   8790 C C     . ALA B 2 361 ? 180.396 171.949 175.974 1.00 66.34  ? 365 ALA F C     1 
ATOM   8791 O O     . ALA B 2 361 ? 181.482 172.434 175.653 1.00 66.34  ? 365 ALA F O     1 
ATOM   8792 C CB    . ALA B 2 361 ? 179.271 172.711 173.897 1.00 66.34  ? 365 ALA F CB    1 
ATOM   8793 N N     . GLY B 2 362 ? 180.058 171.778 177.244 1.00 64.31  ? 366 GLY F N     1 
ATOM   8794 C CA    . GLY B 2 362 ? 180.952 172.162 178.309 1.00 64.31  ? 366 GLY F CA    1 
ATOM   8795 C C     . GLY B 2 362 ? 181.000 173.663 178.500 1.00 64.31  ? 366 GLY F C     1 
ATOM   8796 O O     . GLY B 2 362 ? 180.335 174.422 177.793 1.00 64.31  ? 366 GLY F O     1 
ATOM   8797 N N     . PRO B 2 363 ? 181.788 174.127 179.472 1.00 63.49  ? 367 PRO F N     1 
ATOM   8798 C CA    . PRO B 2 363 ? 181.898 175.572 179.700 1.00 63.49  ? 367 PRO F CA    1 
ATOM   8799 C C     . PRO B 2 363 ? 182.591 176.318 178.579 1.00 63.49  ? 367 PRO F C     1 
ATOM   8800 O O     . PRO B 2 363 ? 182.620 177.551 178.615 1.00 63.49  ? 367 PRO F O     1 
ATOM   8801 C CB    . PRO B 2 363 ? 182.707 175.664 180.997 1.00 63.49  ? 367 PRO F CB    1 
ATOM   8802 C CG    . PRO B 2 363 ? 182.589 174.338 181.624 1.00 63.49  ? 367 PRO F CG    1 
ATOM   8803 C CD    . PRO B 2 363 ? 182.502 173.361 180.500 1.00 63.49  ? 367 PRO F CD    1 
ATOM   8804 N N     . SER B 2 364 ? 183.150 175.627 177.589 1.00 63.33  ? 368 SER F N     1 
ATOM   8805 C CA    . SER B 2 364 ? 183.773 176.316 176.468 1.00 63.33  ? 368 SER F CA    1 
ATOM   8806 C C     . SER B 2 364 ? 182.774 177.096 175.632 1.00 63.33  ? 368 SER F C     1 
ATOM   8807 O O     . SER B 2 364 ? 183.181 177.974 174.868 1.00 63.33  ? 368 SER F O     1 
ATOM   8808 C CB    . SER B 2 364 ? 184.496 175.311 175.581 1.00 63.33  ? 368 SER F CB    1 
ATOM   8809 O OG    . SER B 2 364 ? 183.604 174.301 175.150 1.00 63.33  ? 368 SER F OG    1 
ATOM   8810 N N     . ILE B 2 365 ? 181.481 176.806 175.768 1.00 62.81  ? 369 ILE F N     1 
ATOM   8811 C CA    . ILE B 2 365 ? 180.449 177.459 174.986 1.00 62.81  ? 369 ILE F CA    1 
ATOM   8812 C C     . ILE B 2 365 ? 180.394 178.958 175.224 1.00 62.81  ? 369 ILE F C     1 
ATOM   8813 O O     . ILE B 2 365 ? 179.695 179.672 174.507 1.00 62.81  ? 369 ILE F O     1 
ATOM   8814 C CB    . ILE B 2 365 ? 179.093 176.801 175.309 1.00 62.81  ? 369 ILE F CB    1 
ATOM   8815 C CG1   . ILE B 2 365 ? 178.027 177.219 174.304 1.00 62.81  ? 369 ILE F CG1   1 
ATOM   8816 C CG2   . ILE B 2 365 ? 178.666 177.163 176.701 1.00 62.81  ? 369 ILE F CG2   1 
ATOM   8817 C CD1   . ILE B 2 365 ? 178.354 176.837 172.898 1.00 62.81  ? 369 ILE F CD1   1 
ATOM   8818 N N     . VAL B 2 366 ? 181.134 179.461 176.208 1.00 60.34  ? 370 VAL F N     1 
ATOM   8819 C CA    . VAL B 2 366 ? 181.008 180.863 176.570 1.00 60.34  ? 370 VAL F CA    1 
ATOM   8820 C C     . VAL B 2 366 ? 181.672 181.760 175.544 1.00 60.34  ? 370 VAL F C     1 
ATOM   8821 O O     . VAL B 2 366 ? 181.200 182.871 175.286 1.00 60.34  ? 370 VAL F O     1 
ATOM   8822 C CB    . VAL B 2 366 ? 181.598 181.082 177.964 1.00 60.34  ? 370 VAL F CB    1 
ATOM   8823 C CG1   . VAL B 2 366 ? 181.382 182.503 178.403 1.00 60.34  ? 370 VAL F CG1   1 
ATOM   8824 C CG2   . VAL B 2 366 ? 180.972 180.124 178.903 1.00 60.34  ? 370 VAL F CG2   1 
ATOM   8825 N N     . HIS B 2 367 ? 182.761 181.310 174.941 1.00 60.40  ? 371 HIS F N     1 
ATOM   8826 C CA    . HIS B 2 367 ? 183.514 182.138 174.015 1.00 60.40  ? 371 HIS F CA    1 
ATOM   8827 C C     . HIS B 2 367 ? 183.047 181.995 172.576 1.00 60.40  ? 371 HIS F C     1 
ATOM   8828 O O     . HIS B 2 367 ? 183.599 182.657 171.695 1.00 60.40  ? 371 HIS F O     1 
ATOM   8829 C CB    . HIS B 2 367 ? 184.996 181.805 174.119 1.00 60.40  ? 371 HIS F CB    1 
ATOM   8830 C CG    . HIS B 2 367 ? 185.500 181.782 175.523 1.00 60.40  ? 371 HIS F CG    1 
ATOM   8831 N ND1   . HIS B 2 367 ? 185.932 180.629 176.139 1.00 60.40  ? 371 HIS F ND1   1 
ATOM   8832 C CD2   . HIS B 2 367 ? 185.630 182.770 176.437 1.00 60.40  ? 371 HIS F CD2   1 
ATOM   8833 C CE1   . HIS B 2 367 ? 186.312 180.909 177.372 1.00 60.40  ? 371 HIS F CE1   1 
ATOM   8834 N NE2   . HIS B 2 367 ? 186.134 182.200 177.579 1.00 60.40  ? 371 HIS F NE2   1 
ATOM   8835 N N     . ARG B 2 368 ? 182.029 181.182 172.322 1.00 65.90  ? 372 ARG F N     1 
ATOM   8836 C CA    . ARG B 2 368 ? 181.534 180.974 170.970 1.00 65.90  ? 372 ARG F CA    1 
ATOM   8837 C C     . ARG B 2 368 ? 180.739 182.197 170.529 1.00 65.90  ? 372 ARG F C     1 
ATOM   8838 O O     . ARG B 2 368 ? 180.717 183.228 171.205 1.00 65.90  ? 372 ARG F O     1 
ATOM   8839 C CB    . ARG B 2 368 ? 180.680 179.715 170.903 1.00 65.90  ? 372 ARG F CB    1 
ATOM   8840 C CG    . ARG B 2 368 ? 181.325 178.483 171.488 1.00 65.90  ? 372 ARG F CG    1 
ATOM   8841 C CD    . ARG B 2 368 ? 182.456 177.976 170.634 1.00 65.90  ? 372 ARG F CD    1 
ATOM   8842 N NE    . ARG B 2 368 ? 182.686 176.559 170.880 1.00 65.90  ? 372 ARG F NE    1 
ATOM   8843 C CZ    . ARG B 2 368 ? 183.462 176.088 171.848 1.00 65.90  ? 372 ARG F CZ    1 
ATOM   8844 N NH1   . ARG B 2 368 ? 184.090 176.925 172.660 1.00 65.90  ? 372 ARG F NH1   1 
ATOM   8845 N NH2   . ARG B 2 368 ? 183.611 174.780 172.004 1.00 65.90  ? 372 ARG F NH2   1 
ATOM   8846 N N     . LYS B 2 369 ? 180.074 182.092 169.372 1.00 70.65  ? 373 LYS F N     1 
ATOM   8847 C CA    . LYS B 2 369 ? 179.237 183.184 168.879 1.00 70.65  ? 373 LYS F CA    1 
ATOM   8848 C C     . LYS B 2 369 ? 178.211 183.605 169.920 1.00 70.65  ? 373 LYS F C     1 
ATOM   8849 O O     . LYS B 2 369 ? 177.835 184.782 169.990 1.00 70.65  ? 373 LYS F O     1 
ATOM   8850 C CB    . LYS B 2 369 ? 178.537 182.767 167.584 1.00 70.65  ? 373 LYS F CB    1 
ATOM   8851 C CG    . LYS B 2 369 ? 179.367 182.975 166.328 1.00 70.65  ? 373 LYS F CG    1 
ATOM   8852 C CD    . LYS B 2 369 ? 179.353 184.430 165.885 1.00 70.65  ? 373 LYS F CD    1 
ATOM   8853 C CE    . LYS B 2 369 ? 180.627 184.793 165.139 1.00 70.65  ? 373 LYS F CE    1 
ATOM   8854 N NZ    . LYS B 2 369 ? 181.782 185.010 166.058 1.00 70.65  ? 373 LYS F NZ    1 
ATOM   8855 N N     . CYS B 2 370 ? 177.750 182.656 170.736 1.00 66.39  ? 374 CYS F N     1 
ATOM   8856 C CA    . CYS B 2 370 ? 177.119 182.969 172.013 1.00 66.39  ? 374 CYS F CA    1 
ATOM   8857 C C     . CYS B 2 370 ? 178.206 183.417 172.987 1.00 66.39  ? 374 CYS F C     1 
ATOM   8858 O O     . CYS B 2 370 ? 178.697 182.670 173.828 1.00 66.39  ? 374 CYS F O     1 
ATOM   8859 C CB    . CYS B 2 370 ? 176.318 181.778 172.523 1.00 66.39  ? 374 CYS F CB    1 
ATOM   8860 S SG    . CYS B 2 370 ? 177.233 180.243 172.638 1.00 66.39  ? 374 CYS F SG    1 
ATOM   8861 N N     . PHE B 2 371 ? 178.606 184.667 172.807 1.00 61.50  ? 375 PHE F N     1 
ATOM   8862 C CA    . PHE B 2 371 ? 179.728 185.270 173.503 1.00 61.50  ? 375 PHE F CA    1 
ATOM   8863 C C     . PHE B 2 371 ? 179.446 185.463 174.991 1.00 61.50  ? 375 PHE F C     1 
ATOM   8864 O O     . PHE B 2 371 ? 180.262 186.012 175.722 1.00 61.50  ? 375 PHE F O     1 
ATOM   8865 C CB    . PHE B 2 371 ? 180.056 186.602 172.829 1.00 61.50  ? 375 PHE F CB    1 
ATOM   8866 C CG    . PHE B 2 371 ? 181.350 187.207 173.260 1.00 61.50  ? 375 PHE F CG    1 
ATOM   8867 C CD1   . PHE B 2 371 ? 182.477 186.426 173.408 1.00 61.50  ? 375 PHE F CD1   1 
ATOM   8868 C CD2   . PHE B 2 371 ? 181.448 188.572 173.471 1.00 61.50  ? 375 PHE F CD2   1 
ATOM   8869 C CE1   . PHE B 2 371 ? 183.675 186.984 173.793 1.00 61.50  ? 375 PHE F CE1   1 
ATOM   8870 C CE2   . PHE B 2 371 ? 182.640 189.142 173.856 1.00 61.50  ? 375 PHE F CE2   1 
ATOM   8871 C CZ    . PHE B 2 371 ? 183.761 188.348 174.016 1.00 61.50  ? 375 PHE F CZ    1 
ATOM   8872 O OXT   . PHE B 2 371 ? 178.404 185.076 175.514 1.00 61.50  ? 375 PHE F OXT   1 
HETATM 8873 P PB    . ADP C 3 .   ? 182.135 198.468 190.513 1.00 43.65  ? 401 ADP F PB    1 
HETATM 8874 O O1B   . ADP C 3 .   ? 180.650 198.369 190.304 1.00 43.65  ? 401 ADP F O1B   1 
HETATM 8875 O O2B   . ADP C 3 .   ? 182.601 198.323 191.929 1.00 43.65  ? 401 ADP F O2B   1 
HETATM 8876 O O3B   . ADP C 3 .   ? 182.949 197.694 189.522 1.00 43.65  ? 401 ADP F O3B   1 
HETATM 8877 P PA    . ADP C 3 .   ? 181.543 201.148 190.825 1.00 43.65  ? 401 ADP F PA    1 
HETATM 8878 O O1A   . ADP C 3 .   ? 180.814 201.868 189.730 1.00 43.65  ? 401 ADP F O1A   1 
HETATM 8879 O O2A   . ADP C 3 .   ? 180.809 200.545 191.978 1.00 43.65  ? 401 ADP F O2A   1 
HETATM 8880 O O3A   . ADP C 3 .   ? 182.456 199.997 190.188 1.00 43.65  ? 401 ADP F O3A   1 
HETATM 8881 O "O5'" . ADP C 3 .   ? 182.642 202.119 191.458 1.00 43.65  ? 401 ADP F "O5'" 1 
HETATM 8882 C "C5'" . ADP C 3 .   ? 182.826 202.116 192.865 1.00 43.65  ? 401 ADP F "C5'" 1 
HETATM 8883 C "C4'" . ADP C 3 .   ? 183.939 203.081 193.208 1.00 43.65  ? 401 ADP F "C4'" 1 
HETATM 8884 O "O4'" . ADP C 3 .   ? 183.514 204.384 192.850 1.00 43.65  ? 401 ADP F "O4'" 1 
HETATM 8885 C "C3'" . ADP C 3 .   ? 184.215 203.111 194.694 1.00 43.65  ? 401 ADP F "C3'" 1 
HETATM 8886 O "O3'" . ADP C 3 .   ? 185.533 202.625 194.940 1.00 43.65  ? 401 ADP F "O3'" 1 
HETATM 8887 C "C2'" . ADP C 3 .   ? 184.154 204.561 195.097 1.00 43.65  ? 401 ADP F "C2'" 1 
HETATM 8888 O "O2'" . ADP C 3 .   ? 185.396 204.917 195.705 1.00 43.65  ? 401 ADP F "O2'" 1 
HETATM 8889 C "C1'" . ADP C 3 .   ? 183.966 205.326 193.805 1.00 43.65  ? 401 ADP F "C1'" 1 
HETATM 8890 N N9    . ADP C 3 .   ? 182.959 206.394 193.961 1.00 43.65  ? 401 ADP F N9    1 
HETATM 8891 C C8    . ADP C 3 .   ? 181.647 206.230 194.179 1.00 43.65  ? 401 ADP F C8    1 
HETATM 8892 N N7    . ADP C 3 .   ? 181.010 207.422 194.268 1.00 43.65  ? 401 ADP F N7    1 
HETATM 8893 C C5    . ADP C 3 .   ? 181.937 208.376 194.109 1.00 43.65  ? 401 ADP F C5    1 
HETATM 8894 C C6    . ADP C 3 .   ? 181.958 209.848 194.094 1.00 43.65  ? 401 ADP F C6    1 
HETATM 8895 N N6    . ADP C 3 .   ? 180.830 210.565 194.273 1.00 43.65  ? 401 ADP F N6    1 
HETATM 8896 N N1    . ADP C 3 .   ? 183.139 210.457 193.897 1.00 43.65  ? 401 ADP F N1    1 
HETATM 8897 C C2    . ADP C 3 .   ? 184.267 209.763 193.715 1.00 43.65  ? 401 ADP F C2    1 
HETATM 8898 N N3    . ADP C 3 .   ? 184.328 208.429 193.715 1.00 43.65  ? 401 ADP F N3    1 
HETATM 8899 C C4    . ADP C 3 .   ? 183.216 207.693 193.907 1.00 43.65  ? 401 ADP F C4    1 
# 
